data_8UBV
# 
_entry.id   8UBV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UBV         pdb_00008ubv 10.2210/pdb8ubv/pdb 
WWPDB D_1000277771 ?            ?                   
EMDB  EMD-42106    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-13 
3 'Structure model' 1 2 2024-11-20 
4 'Structure model' 1 3 2024-11-27 
5 'Structure model' 1 4 2025-01-08 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 3 'Structure model' 'Database references' 
5 4 'Structure model' 'Data collection'     
6 5 'Structure model' 'Data collection'     
7 5 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' citation        
5 3 'Structure model' em_admin        
6 4 'Structure model' em_admin        
7 5 'Structure model' citation        
8 5 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.journal_abbrev'          
2  2 'Structure model' '_citation.journal_id_ASTM'         
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.pdbx_database_id_DOI'    
6  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
7  2 'Structure model' '_citation.title'                   
8  2 'Structure model' '_em_admin.last_update'             
9  3 'Structure model' '_citation.country'                 
10 3 'Structure model' '_citation.journal_abbrev'          
11 3 'Structure model' '_citation.journal_id_ASTM'         
12 3 'Structure model' '_citation.journal_id_CSD'          
13 3 'Structure model' '_citation.journal_id_ISSN'         
14 3 'Structure model' '_citation.pdbx_database_id_PubMed' 
15 3 'Structure model' '_citation.title'                   
16 3 'Structure model' '_em_admin.last_update'             
17 4 'Structure model' '_em_admin.last_update'             
18 5 'Structure model' '_citation.journal_volume'          
19 5 'Structure model' '_citation.page_first'              
20 5 'Structure model' '_citation.page_last'               
21 5 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UBV 
_pdbx_database_status.recvd_initial_deposition_date   2023-09-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB .                                                         EMD-42105 'other EM volume'      
EMDB 'Structure of  dimeric FBXL17-BACH1BTB E3 ligase complex' EMD-42106 'associated EM volume' 
EMDB .                                                         EMD-42102 'other EM volume'      
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              nzheng@uw.edu 
_pdbx_contact_author.name_first         Zheng 
_pdbx_contact_author.name_last          Ning 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1039-1581 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Shi, H.'   1 0000-0003-2428-2500 
'Cao, S.'   2 0000-0003-1201-4963 
'Zheng, N.' 3 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Cell 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1097-4172 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            187 
_citation.language                  ? 
_citation.page_first                7568 
_citation.page_last                 7584.e22 
_citation.title                     
'Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.cell.2024.10.012 
_citation.pdbx_database_id_PubMed   39504958 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cao, S.'        1  ? 
primary 'Garcia, S.F.'   2  ? 
primary 'Shi, H.'        3  ? 
primary 'James, E.I.'    4  ? 
primary 'Kito, Y.'       5  ? 
primary 'Shi, H.'        6  ? 
primary 'Mao, H.'        7  ? 
primary 'Kaisari, S.'    8  ? 
primary 'Rona, G.'       9  ? 
primary 'Deng, S.'       10 ? 
primary 'Goldberg, H.V.' 11 ? 
primary 'Ponce, J.'      12 ? 
primary 'Ueberheide, B.' 13 ? 
primary 'Lignitto, L.'   14 ? 
primary 'Guttman, M.'    15 ? 
primary 'Pagano, M.'     16 ? 
primary 'Zheng, N.'      17 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'F-box/LRR-repeat protein 17'           44505.512 2 ? ? 'UNP residues 310-701'            ? 
2 polymer man 'Transcription regulator protein BACH1' 13839.761 2 ? ? 'BTB domain (UNP residues 7-128)' ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;CHREPPPETPDINQLPPSILLKIFSNLSLDERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNII
EINISDCRSMSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDI
HFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRH
ITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKE
ITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAASS
;
;CHREPPPETPDINQLPPSILLKIFSNLSLDERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNII
EINISDCRSMSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDI
HFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRH
ITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKE
ITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAASS
;
B,H ? 
2 'polypeptide(L)' no no 
;SVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKF
;
;SVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKF
;
C,I ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   CYS n 
1 2   HIS n 
1 3   ARG n 
1 4   GLU n 
1 5   PRO n 
1 6   PRO n 
1 7   PRO n 
1 8   GLU n 
1 9   THR n 
1 10  PRO n 
1 11  ASP n 
1 12  ILE n 
1 13  ASN n 
1 14  GLN n 
1 15  LEU n 
1 16  PRO n 
1 17  PRO n 
1 18  SER n 
1 19  ILE n 
1 20  LEU n 
1 21  LEU n 
1 22  LYS n 
1 23  ILE n 
1 24  PHE n 
1 25  SER n 
1 26  ASN n 
1 27  LEU n 
1 28  SER n 
1 29  LEU n 
1 30  ASP n 
1 31  GLU n 
1 32  ARG n 
1 33  CYS n 
1 34  LEU n 
1 35  SER n 
1 36  ALA n 
1 37  SER n 
1 38  LEU n 
1 39  VAL n 
1 40  CYS n 
1 41  LYS n 
1 42  TYR n 
1 43  TRP n 
1 44  ARG n 
1 45  ASP n 
1 46  LEU n 
1 47  CYS n 
1 48  LEU n 
1 49  ASP n 
1 50  PHE n 
1 51  GLN n 
1 52  PHE n 
1 53  TRP n 
1 54  LYS n 
1 55  GLN n 
1 56  LEU n 
1 57  ASP n 
1 58  LEU n 
1 59  SER n 
1 60  SER n 
1 61  ARG n 
1 62  GLN n 
1 63  GLN n 
1 64  VAL n 
1 65  THR n 
1 66  ASP n 
1 67  GLU n 
1 68  LEU n 
1 69  LEU n 
1 70  GLU n 
1 71  LYS n 
1 72  ILE n 
1 73  ALA n 
1 74  SER n 
1 75  ARG n 
1 76  SER n 
1 77  GLN n 
1 78  ASN n 
1 79  ILE n 
1 80  ILE n 
1 81  GLU n 
1 82  ILE n 
1 83  ASN n 
1 84  ILE n 
1 85  SER n 
1 86  ASP n 
1 87  CYS n 
1 88  ARG n 
1 89  SER n 
1 90  MET n 
1 91  SER n 
1 92  ASP n 
1 93  ASN n 
1 94  GLY n 
1 95  VAL n 
1 96  CYS n 
1 97  VAL n 
1 98  LEU n 
1 99  ALA n 
1 100 PHE n 
1 101 LYS n 
1 102 CYS n 
1 103 PRO n 
1 104 GLY n 
1 105 LEU n 
1 106 LEU n 
1 107 ARG n 
1 108 TYR n 
1 109 THR n 
1 110 ALA n 
1 111 TYR n 
1 112 ARG n 
1 113 CYS n 
1 114 LYS n 
1 115 GLN n 
1 116 LEU n 
1 117 SER n 
1 118 ASP n 
1 119 THR n 
1 120 SER n 
1 121 ILE n 
1 122 ILE n 
1 123 ALA n 
1 124 VAL n 
1 125 ALA n 
1 126 SER n 
1 127 HIS n 
1 128 CYS n 
1 129 PRO n 
1 130 LEU n 
1 131 LEU n 
1 132 GLN n 
1 133 LYS n 
1 134 VAL n 
1 135 HIS n 
1 136 VAL n 
1 137 GLY n 
1 138 ASN n 
1 139 GLN n 
1 140 ASP n 
1 141 LYS n 
1 142 LEU n 
1 143 THR n 
1 144 ASP n 
1 145 GLU n 
1 146 GLY n 
1 147 LEU n 
1 148 LYS n 
1 149 GLN n 
1 150 LEU n 
1 151 GLY n 
1 152 SER n 
1 153 LYS n 
1 154 CYS n 
1 155 ARG n 
1 156 GLU n 
1 157 LEU n 
1 158 LYS n 
1 159 ASP n 
1 160 ILE n 
1 161 HIS n 
1 162 PHE n 
1 163 GLY n 
1 164 GLN n 
1 165 CYS n 
1 166 TYR n 
1 167 LYS n 
1 168 ILE n 
1 169 SER n 
1 170 ASP n 
1 171 GLU n 
1 172 GLY n 
1 173 MET n 
1 174 ILE n 
1 175 VAL n 
1 176 ILE n 
1 177 ALA n 
1 178 LYS n 
1 179 GLY n 
1 180 CYS n 
1 181 LEU n 
1 182 LYS n 
1 183 LEU n 
1 184 GLN n 
1 185 ARG n 
1 186 ILE n 
1 187 TYR n 
1 188 MET n 
1 189 GLN n 
1 190 GLU n 
1 191 ASN n 
1 192 LYS n 
1 193 LEU n 
1 194 VAL n 
1 195 THR n 
1 196 ASP n 
1 197 GLN n 
1 198 SER n 
1 199 VAL n 
1 200 LYS n 
1 201 ALA n 
1 202 PHE n 
1 203 ALA n 
1 204 GLU n 
1 205 HIS n 
1 206 CYS n 
1 207 PRO n 
1 208 GLU n 
1 209 LEU n 
1 210 GLN n 
1 211 TYR n 
1 212 VAL n 
1 213 GLY n 
1 214 PHE n 
1 215 MET n 
1 216 GLY n 
1 217 CYS n 
1 218 SER n 
1 219 VAL n 
1 220 THR n 
1 221 SER n 
1 222 LYS n 
1 223 GLY n 
1 224 VAL n 
1 225 ILE n 
1 226 HIS n 
1 227 LEU n 
1 228 THR n 
1 229 LYS n 
1 230 LEU n 
1 231 ARG n 
1 232 ASN n 
1 233 LEU n 
1 234 SER n 
1 235 SER n 
1 236 LEU n 
1 237 ASP n 
1 238 LEU n 
1 239 ARG n 
1 240 HIS n 
1 241 ILE n 
1 242 THR n 
1 243 GLU n 
1 244 LEU n 
1 245 ASP n 
1 246 ASN n 
1 247 GLU n 
1 248 THR n 
1 249 VAL n 
1 250 MET n 
1 251 GLU n 
1 252 ILE n 
1 253 VAL n 
1 254 LYS n 
1 255 ARG n 
1 256 CYS n 
1 257 LYS n 
1 258 ASN n 
1 259 LEU n 
1 260 SER n 
1 261 SER n 
1 262 LEU n 
1 263 ASN n 
1 264 LEU n 
1 265 CYS n 
1 266 LEU n 
1 267 ASN n 
1 268 TRP n 
1 269 ILE n 
1 270 ILE n 
1 271 ASN n 
1 272 ASP n 
1 273 ARG n 
1 274 CYS n 
1 275 VAL n 
1 276 GLU n 
1 277 VAL n 
1 278 ILE n 
1 279 ALA n 
1 280 LYS n 
1 281 GLU n 
1 282 GLY n 
1 283 GLN n 
1 284 ASN n 
1 285 LEU n 
1 286 LYS n 
1 287 GLU n 
1 288 LEU n 
1 289 TYR n 
1 290 LEU n 
1 291 VAL n 
1 292 SER n 
1 293 CYS n 
1 294 LYS n 
1 295 ILE n 
1 296 THR n 
1 297 ASP n 
1 298 TYR n 
1 299 ALA n 
1 300 LEU n 
1 301 ILE n 
1 302 ALA n 
1 303 ILE n 
1 304 GLY n 
1 305 ARG n 
1 306 TYR n 
1 307 SER n 
1 308 MET n 
1 309 THR n 
1 310 ILE n 
1 311 GLU n 
1 312 THR n 
1 313 VAL n 
1 314 ASP n 
1 315 VAL n 
1 316 GLY n 
1 317 TRP n 
1 318 CYS n 
1 319 LYS n 
1 320 GLU n 
1 321 ILE n 
1 322 THR n 
1 323 ASP n 
1 324 GLN n 
1 325 GLY n 
1 326 ALA n 
1 327 THR n 
1 328 LEU n 
1 329 ILE n 
1 330 ALA n 
1 331 GLN n 
1 332 SER n 
1 333 SER n 
1 334 LYS n 
1 335 SER n 
1 336 LEU n 
1 337 ARG n 
1 338 TYR n 
1 339 LEU n 
1 340 GLY n 
1 341 LEU n 
1 342 MET n 
1 343 ARG n 
1 344 CYS n 
1 345 ASP n 
1 346 LYS n 
1 347 VAL n 
1 348 ASN n 
1 349 GLU n 
1 350 VAL n 
1 351 THR n 
1 352 VAL n 
1 353 GLU n 
1 354 GLN n 
1 355 LEU n 
1 356 VAL n 
1 357 GLN n 
1 358 GLN n 
1 359 TYR n 
1 360 PRO n 
1 361 HIS n 
1 362 ILE n 
1 363 THR n 
1 364 PHE n 
1 365 SER n 
1 366 THR n 
1 367 VAL n 
1 368 LEU n 
1 369 GLN n 
1 370 ASP n 
1 371 CYS n 
1 372 LYS n 
1 373 ARG n 
1 374 THR n 
1 375 LEU n 
1 376 GLU n 
1 377 ARG n 
1 378 ALA n 
1 379 TYR n 
1 380 GLN n 
1 381 MET n 
1 382 GLY n 
1 383 TRP n 
1 384 THR n 
1 385 PRO n 
1 386 ASN n 
1 387 MET n 
1 388 SER n 
1 389 ALA n 
1 390 ALA n 
1 391 SER n 
1 392 SER n 
2 1   SER n 
2 2   VAL n 
2 3   PHE n 
2 4   ALA n 
2 5   TYR n 
2 6   GLU n 
2 7   SER n 
2 8   SER n 
2 9   VAL n 
2 10  HIS n 
2 11  SER n 
2 12  THR n 
2 13  ASN n 
2 14  VAL n 
2 15  LEU n 
2 16  LEU n 
2 17  SER n 
2 18  LEU n 
2 19  ASN n 
2 20  ASP n 
2 21  GLN n 
2 22  ARG n 
2 23  LYS n 
2 24  LYS n 
2 25  ASP n 
2 26  VAL n 
2 27  LEU n 
2 28  CYS n 
2 29  ASP n 
2 30  VAL n 
2 31  THR n 
2 32  ILE n 
2 33  PHE n 
2 34  VAL n 
2 35  GLU n 
2 36  GLY n 
2 37  GLN n 
2 38  ARG n 
2 39  PHE n 
2 40  ARG n 
2 41  ALA n 
2 42  HIS n 
2 43  ARG n 
2 44  SER n 
2 45  VAL n 
2 46  LEU n 
2 47  ALA n 
2 48  ALA n 
2 49  CYS n 
2 50  SER n 
2 51  SER n 
2 52  TYR n 
2 53  PHE n 
2 54  HIS n 
2 55  SER n 
2 56  ARG n 
2 57  ILE n 
2 58  VAL n 
2 59  GLY n 
2 60  GLN n 
2 61  ALA n 
2 62  ASP n 
2 63  GLY n 
2 64  GLU n 
2 65  LEU n 
2 66  ASN n 
2 67  ILE n 
2 68  THR n 
2 69  LEU n 
2 70  PRO n 
2 71  GLU n 
2 72  GLU n 
2 73  VAL n 
2 74  THR n 
2 75  VAL n 
2 76  LYS n 
2 77  GLY n 
2 78  PHE n 
2 79  GLU n 
2 80  PRO n 
2 81  LEU n 
2 82  ILE n 
2 83  GLN n 
2 84  PHE n 
2 85  ALA n 
2 86  TYR n 
2 87  THR n 
2 88  ALA n 
2 89  LYS n 
2 90  LEU n 
2 91  ILE n 
2 92  LEU n 
2 93  SER n 
2 94  LYS n 
2 95  GLU n 
2 96  ASN n 
2 97  VAL n 
2 98  ASP n 
2 99  GLU n 
2 100 VAL n 
2 101 CYS n 
2 102 LYS n 
2 103 CYS n 
2 104 VAL n 
2 105 GLU n 
2 106 PHE n 
2 107 LEU n 
2 108 SER n 
2 109 VAL n 
2 110 HIS n 
2 111 ASN n 
2 112 ILE n 
2 113 GLU n 
2 114 GLU n 
2 115 SER n 
2 116 CYS n 
2 117 PHE n 
2 118 GLN n 
2 119 PHE n 
2 120 LEU n 
2 121 LYS n 
2 122 PHE n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 392 human ? FBXL17 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'cabbage looper' 
'Trichoplusia ni'       7111   ? ? ? ? ? ? ? ? BL21 ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 122 human ? BACH1  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ?                
'Escherichia coli BL21' 511693 ? ? ? ? ? ? ? ? ?    ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   CYS 1   310 ?   ?   ?   B . n 
A 1 2   HIS 2   311 ?   ?   ?   B . n 
A 1 3   ARG 3   312 ?   ?   ?   B . n 
A 1 4   GLU 4   313 ?   ?   ?   B . n 
A 1 5   PRO 5   314 ?   ?   ?   B . n 
A 1 6   PRO 6   315 ?   ?   ?   B . n 
A 1 7   PRO 7   316 ?   ?   ?   B . n 
A 1 8   GLU 8   317 ?   ?   ?   B . n 
A 1 9   THR 9   318 ?   ?   ?   B . n 
A 1 10  PRO 10  319 ?   ?   ?   B . n 
A 1 11  ASP 11  320 ?   ?   ?   B . n 
A 1 12  ILE 12  321 ?   ?   ?   B . n 
A 1 13  ASN 13  322 ?   ?   ?   B . n 
A 1 14  GLN 14  323 ?   ?   ?   B . n 
A 1 15  LEU 15  324 ?   ?   ?   B . n 
A 1 16  PRO 16  325 ?   ?   ?   B . n 
A 1 17  PRO 17  326 ?   ?   ?   B . n 
A 1 18  SER 18  327 ?   ?   ?   B . n 
A 1 19  ILE 19  328 ?   ?   ?   B . n 
A 1 20  LEU 20  329 ?   ?   ?   B . n 
A 1 21  LEU 21  330 ?   ?   ?   B . n 
A 1 22  LYS 22  331 ?   ?   ?   B . n 
A 1 23  ILE 23  332 ?   ?   ?   B . n 
A 1 24  PHE 24  333 ?   ?   ?   B . n 
A 1 25  SER 25  334 ?   ?   ?   B . n 
A 1 26  ASN 26  335 ?   ?   ?   B . n 
A 1 27  LEU 27  336 ?   ?   ?   B . n 
A 1 28  SER 28  337 ?   ?   ?   B . n 
A 1 29  LEU 29  338 ?   ?   ?   B . n 
A 1 30  ASP 30  339 ?   ?   ?   B . n 
A 1 31  GLU 31  340 ?   ?   ?   B . n 
A 1 32  ARG 32  341 ?   ?   ?   B . n 
A 1 33  CYS 33  342 ?   ?   ?   B . n 
A 1 34  LEU 34  343 ?   ?   ?   B . n 
A 1 35  SER 35  344 ?   ?   ?   B . n 
A 1 36  ALA 36  345 ?   ?   ?   B . n 
A 1 37  SER 37  346 ?   ?   ?   B . n 
A 1 38  LEU 38  347 ?   ?   ?   B . n 
A 1 39  VAL 39  348 ?   ?   ?   B . n 
A 1 40  CYS 40  349 ?   ?   ?   B . n 
A 1 41  LYS 41  350 ?   ?   ?   B . n 
A 1 42  TYR 42  351 ?   ?   ?   B . n 
A 1 43  TRP 43  352 ?   ?   ?   B . n 
A 1 44  ARG 44  353 ?   ?   ?   B . n 
A 1 45  ASP 45  354 ?   ?   ?   B . n 
A 1 46  LEU 46  355 ?   ?   ?   B . n 
A 1 47  CYS 47  356 ?   ?   ?   B . n 
A 1 48  LEU 48  357 ?   ?   ?   B . n 
A 1 49  ASP 49  358 ?   ?   ?   B . n 
A 1 50  PHE 50  359 ?   ?   ?   B . n 
A 1 51  GLN 51  360 ?   ?   ?   B . n 
A 1 52  PHE 52  361 ?   ?   ?   B . n 
A 1 53  TRP 53  362 ?   ?   ?   B . n 
A 1 54  LYS 54  363 363 LYS LYS B . n 
A 1 55  GLN 55  364 364 GLN GLN B . n 
A 1 56  LEU 56  365 365 LEU LEU B . n 
A 1 57  ASP 57  366 366 ASP ASP B . n 
A 1 58  LEU 58  367 367 LEU LEU B . n 
A 1 59  SER 59  368 368 SER SER B . n 
A 1 60  SER 60  369 369 SER SER B . n 
A 1 61  ARG 61  370 370 ARG ARG B . n 
A 1 62  GLN 62  371 371 GLN GLN B . n 
A 1 63  GLN 63  372 372 GLN GLN B . n 
A 1 64  VAL 64  373 373 VAL VAL B . n 
A 1 65  THR 65  374 374 THR THR B . n 
A 1 66  ASP 66  375 375 ASP ASP B . n 
A 1 67  GLU 67  376 376 GLU GLU B . n 
A 1 68  LEU 68  377 377 LEU LEU B . n 
A 1 69  LEU 69  378 378 LEU LEU B . n 
A 1 70  GLU 70  379 379 GLU GLU B . n 
A 1 71  LYS 71  380 380 LYS LYS B . n 
A 1 72  ILE 72  381 381 ILE ILE B . n 
A 1 73  ALA 73  382 382 ALA ALA B . n 
A 1 74  SER 74  383 383 SER SER B . n 
A 1 75  ARG 75  384 384 ARG ARG B . n 
A 1 76  SER 76  385 385 SER SER B . n 
A 1 77  GLN 77  386 386 GLN GLN B . n 
A 1 78  ASN 78  387 387 ASN ASN B . n 
A 1 79  ILE 79  388 388 ILE ILE B . n 
A 1 80  ILE 80  389 389 ILE ILE B . n 
A 1 81  GLU 81  390 390 GLU GLU B . n 
A 1 82  ILE 82  391 391 ILE ILE B . n 
A 1 83  ASN 83  392 392 ASN ASN B . n 
A 1 84  ILE 84  393 393 ILE ILE B . n 
A 1 85  SER 85  394 394 SER SER B . n 
A 1 86  ASP 86  395 395 ASP ASP B . n 
A 1 87  CYS 87  396 396 CYS CYS B . n 
A 1 88  ARG 88  397 397 ARG ARG B . n 
A 1 89  SER 89  398 398 SER SER B . n 
A 1 90  MET 90  399 399 MET MET B . n 
A 1 91  SER 91  400 400 SER SER B . n 
A 1 92  ASP 92  401 401 ASP ASP B . n 
A 1 93  ASN 93  402 402 ASN ASN B . n 
A 1 94  GLY 94  403 403 GLY GLY B . n 
A 1 95  VAL 95  404 404 VAL VAL B . n 
A 1 96  CYS 96  405 405 CYS CYS B . n 
A 1 97  VAL 97  406 406 VAL VAL B . n 
A 1 98  LEU 98  407 407 LEU LEU B . n 
A 1 99  ALA 99  408 408 ALA ALA B . n 
A 1 100 PHE 100 409 409 PHE PHE B . n 
A 1 101 LYS 101 410 410 LYS LYS B . n 
A 1 102 CYS 102 411 411 CYS CYS B . n 
A 1 103 PRO 103 412 412 PRO PRO B . n 
A 1 104 GLY 104 413 413 GLY GLY B . n 
A 1 105 LEU 105 414 414 LEU LEU B . n 
A 1 106 LEU 106 415 415 LEU LEU B . n 
A 1 107 ARG 107 416 416 ARG ARG B . n 
A 1 108 TYR 108 417 417 TYR TYR B . n 
A 1 109 THR 109 418 418 THR THR B . n 
A 1 110 ALA 110 419 419 ALA ALA B . n 
A 1 111 TYR 111 420 420 TYR TYR B . n 
A 1 112 ARG 112 421 421 ARG ARG B . n 
A 1 113 CYS 113 422 422 CYS CYS B . n 
A 1 114 LYS 114 423 423 LYS LYS B . n 
A 1 115 GLN 115 424 424 GLN GLN B . n 
A 1 116 LEU 116 425 425 LEU LEU B . n 
A 1 117 SER 117 426 426 SER SER B . n 
A 1 118 ASP 118 427 427 ASP ASP B . n 
A 1 119 THR 119 428 428 THR THR B . n 
A 1 120 SER 120 429 429 SER SER B . n 
A 1 121 ILE 121 430 430 ILE ILE B . n 
A 1 122 ILE 122 431 431 ILE ILE B . n 
A 1 123 ALA 123 432 432 ALA ALA B . n 
A 1 124 VAL 124 433 433 VAL VAL B . n 
A 1 125 ALA 125 434 434 ALA ALA B . n 
A 1 126 SER 126 435 435 SER SER B . n 
A 1 127 HIS 127 436 436 HIS HIS B . n 
A 1 128 CYS 128 437 437 CYS CYS B . n 
A 1 129 PRO 129 438 438 PRO PRO B . n 
A 1 130 LEU 130 439 439 LEU LEU B . n 
A 1 131 LEU 131 440 440 LEU LEU B . n 
A 1 132 GLN 132 441 441 GLN GLN B . n 
A 1 133 LYS 133 442 442 LYS LYS B . n 
A 1 134 VAL 134 443 443 VAL VAL B . n 
A 1 135 HIS 135 444 444 HIS HIS B . n 
A 1 136 VAL 136 445 445 VAL VAL B . n 
A 1 137 GLY 137 446 446 GLY GLY B . n 
A 1 138 ASN 138 447 447 ASN ASN B . n 
A 1 139 GLN 139 448 448 GLN GLN B . n 
A 1 140 ASP 140 449 449 ASP ASP B . n 
A 1 141 LYS 141 450 450 LYS LYS B . n 
A 1 142 LEU 142 451 451 LEU LEU B . n 
A 1 143 THR 143 452 452 THR THR B . n 
A 1 144 ASP 144 453 453 ASP ASP B . n 
A 1 145 GLU 145 454 454 GLU GLU B . n 
A 1 146 GLY 146 455 455 GLY GLY B . n 
A 1 147 LEU 147 456 456 LEU LEU B . n 
A 1 148 LYS 148 457 457 LYS LYS B . n 
A 1 149 GLN 149 458 458 GLN GLN B . n 
A 1 150 LEU 150 459 459 LEU LEU B . n 
A 1 151 GLY 151 460 460 GLY GLY B . n 
A 1 152 SER 152 461 461 SER SER B . n 
A 1 153 LYS 153 462 462 LYS LYS B . n 
A 1 154 CYS 154 463 463 CYS CYS B . n 
A 1 155 ARG 155 464 464 ARG ARG B . n 
A 1 156 GLU 156 465 465 GLU GLU B . n 
A 1 157 LEU 157 466 466 LEU LEU B . n 
A 1 158 LYS 158 467 467 LYS LYS B . n 
A 1 159 ASP 159 468 468 ASP ASP B . n 
A 1 160 ILE 160 469 469 ILE ILE B . n 
A 1 161 HIS 161 470 470 HIS HIS B . n 
A 1 162 PHE 162 471 471 PHE PHE B . n 
A 1 163 GLY 163 472 472 GLY GLY B . n 
A 1 164 GLN 164 473 473 GLN GLN B . n 
A 1 165 CYS 165 474 474 CYS CYS B . n 
A 1 166 TYR 166 475 475 TYR TYR B . n 
A 1 167 LYS 167 476 476 LYS LYS B . n 
A 1 168 ILE 168 477 477 ILE ILE B . n 
A 1 169 SER 169 478 478 SER SER B . n 
A 1 170 ASP 170 479 479 ASP ASP B . n 
A 1 171 GLU 171 480 480 GLU GLU B . n 
A 1 172 GLY 172 481 481 GLY GLY B . n 
A 1 173 MET 173 482 482 MET MET B . n 
A 1 174 ILE 174 483 483 ILE ILE B . n 
A 1 175 VAL 175 484 484 VAL VAL B . n 
A 1 176 ILE 176 485 485 ILE ILE B . n 
A 1 177 ALA 177 486 486 ALA ALA B . n 
A 1 178 LYS 178 487 487 LYS LYS B . n 
A 1 179 GLY 179 488 488 GLY GLY B . n 
A 1 180 CYS 180 489 489 CYS CYS B . n 
A 1 181 LEU 181 490 490 LEU LEU B . n 
A 1 182 LYS 182 491 491 LYS LYS B . n 
A 1 183 LEU 183 492 492 LEU LEU B . n 
A 1 184 GLN 184 493 493 GLN GLN B . n 
A 1 185 ARG 185 494 494 ARG ARG B . n 
A 1 186 ILE 186 495 495 ILE ILE B . n 
A 1 187 TYR 187 496 496 TYR TYR B . n 
A 1 188 MET 188 497 497 MET MET B . n 
A 1 189 GLN 189 498 498 GLN GLN B . n 
A 1 190 GLU 190 499 499 GLU GLU B . n 
A 1 191 ASN 191 500 500 ASN ASN B . n 
A 1 192 LYS 192 501 501 LYS LYS B . n 
A 1 193 LEU 193 502 502 LEU LEU B . n 
A 1 194 VAL 194 503 503 VAL VAL B . n 
A 1 195 THR 195 504 504 THR THR B . n 
A 1 196 ASP 196 505 505 ASP ASP B . n 
A 1 197 GLN 197 506 506 GLN GLN B . n 
A 1 198 SER 198 507 507 SER SER B . n 
A 1 199 VAL 199 508 508 VAL VAL B . n 
A 1 200 LYS 200 509 509 LYS LYS B . n 
A 1 201 ALA 201 510 510 ALA ALA B . n 
A 1 202 PHE 202 511 511 PHE PHE B . n 
A 1 203 ALA 203 512 512 ALA ALA B . n 
A 1 204 GLU 204 513 513 GLU GLU B . n 
A 1 205 HIS 205 514 514 HIS HIS B . n 
A 1 206 CYS 206 515 515 CYS CYS B . n 
A 1 207 PRO 207 516 516 PRO PRO B . n 
A 1 208 GLU 208 517 517 GLU GLU B . n 
A 1 209 LEU 209 518 518 LEU LEU B . n 
A 1 210 GLN 210 519 519 GLN GLN B . n 
A 1 211 TYR 211 520 520 TYR TYR B . n 
A 1 212 VAL 212 521 521 VAL VAL B . n 
A 1 213 GLY 213 522 522 GLY GLY B . n 
A 1 214 PHE 214 523 523 PHE PHE B . n 
A 1 215 MET 215 524 524 MET MET B . n 
A 1 216 GLY 216 525 525 GLY GLY B . n 
A 1 217 CYS 217 526 526 CYS CYS B . n 
A 1 218 SER 218 527 527 SER SER B . n 
A 1 219 VAL 219 528 528 VAL VAL B . n 
A 1 220 THR 220 529 529 THR THR B . n 
A 1 221 SER 221 530 530 SER SER B . n 
A 1 222 LYS 222 531 531 LYS LYS B . n 
A 1 223 GLY 223 532 532 GLY GLY B . n 
A 1 224 VAL 224 533 533 VAL VAL B . n 
A 1 225 ILE 225 534 534 ILE ILE B . n 
A 1 226 HIS 226 535 535 HIS HIS B . n 
A 1 227 LEU 227 536 536 LEU LEU B . n 
A 1 228 THR 228 537 537 THR THR B . n 
A 1 229 LYS 229 538 538 LYS LYS B . n 
A 1 230 LEU 230 539 539 LEU LEU B . n 
A 1 231 ARG 231 540 540 ARG ARG B . n 
A 1 232 ASN 232 541 541 ASN ASN B . n 
A 1 233 LEU 233 542 542 LEU LEU B . n 
A 1 234 SER 234 543 543 SER SER B . n 
A 1 235 SER 235 544 544 SER SER B . n 
A 1 236 LEU 236 545 545 LEU LEU B . n 
A 1 237 ASP 237 546 546 ASP ASP B . n 
A 1 238 LEU 238 547 547 LEU LEU B . n 
A 1 239 ARG 239 548 548 ARG ARG B . n 
A 1 240 HIS 240 549 549 HIS HIS B . n 
A 1 241 ILE 241 550 550 ILE ILE B . n 
A 1 242 THR 242 551 551 THR THR B . n 
A 1 243 GLU 243 552 552 GLU GLU B . n 
A 1 244 LEU 244 553 553 LEU LEU B . n 
A 1 245 ASP 245 554 554 ASP ASP B . n 
A 1 246 ASN 246 555 555 ASN ASN B . n 
A 1 247 GLU 247 556 556 GLU GLU B . n 
A 1 248 THR 248 557 557 THR THR B . n 
A 1 249 VAL 249 558 558 VAL VAL B . n 
A 1 250 MET 250 559 559 MET MET B . n 
A 1 251 GLU 251 560 560 GLU GLU B . n 
A 1 252 ILE 252 561 561 ILE ILE B . n 
A 1 253 VAL 253 562 562 VAL VAL B . n 
A 1 254 LYS 254 563 563 LYS LYS B . n 
A 1 255 ARG 255 564 564 ARG ARG B . n 
A 1 256 CYS 256 565 565 CYS CYS B . n 
A 1 257 LYS 257 566 566 LYS LYS B . n 
A 1 258 ASN 258 567 567 ASN ASN B . n 
A 1 259 LEU 259 568 568 LEU LEU B . n 
A 1 260 SER 260 569 569 SER SER B . n 
A 1 261 SER 261 570 570 SER SER B . n 
A 1 262 LEU 262 571 571 LEU LEU B . n 
A 1 263 ASN 263 572 572 ASN ASN B . n 
A 1 264 LEU 264 573 573 LEU LEU B . n 
A 1 265 CYS 265 574 574 CYS CYS B . n 
A 1 266 LEU 266 575 575 LEU LEU B . n 
A 1 267 ASN 267 576 576 ASN ASN B . n 
A 1 268 TRP 268 577 577 TRP TRP B . n 
A 1 269 ILE 269 578 578 ILE ILE B . n 
A 1 270 ILE 270 579 579 ILE ILE B . n 
A 1 271 ASN 271 580 580 ASN ASN B . n 
A 1 272 ASP 272 581 581 ASP ASP B . n 
A 1 273 ARG 273 582 582 ARG ARG B . n 
A 1 274 CYS 274 583 583 CYS CYS B . n 
A 1 275 VAL 275 584 584 VAL VAL B . n 
A 1 276 GLU 276 585 585 GLU GLU B . n 
A 1 277 VAL 277 586 586 VAL VAL B . n 
A 1 278 ILE 278 587 587 ILE ILE B . n 
A 1 279 ALA 279 588 588 ALA ALA B . n 
A 1 280 LYS 280 589 589 LYS LYS B . n 
A 1 281 GLU 281 590 590 GLU GLU B . n 
A 1 282 GLY 282 591 591 GLY GLY B . n 
A 1 283 GLN 283 592 592 GLN GLN B . n 
A 1 284 ASN 284 593 593 ASN ASN B . n 
A 1 285 LEU 285 594 594 LEU LEU B . n 
A 1 286 LYS 286 595 595 LYS LYS B . n 
A 1 287 GLU 287 596 596 GLU GLU B . n 
A 1 288 LEU 288 597 597 LEU LEU B . n 
A 1 289 TYR 289 598 598 TYR TYR B . n 
A 1 290 LEU 290 599 599 LEU LEU B . n 
A 1 291 VAL 291 600 600 VAL VAL B . n 
A 1 292 SER 292 601 601 SER SER B . n 
A 1 293 CYS 293 602 602 CYS CYS B . n 
A 1 294 LYS 294 603 603 LYS LYS B . n 
A 1 295 ILE 295 604 604 ILE ILE B . n 
A 1 296 THR 296 605 605 THR THR B . n 
A 1 297 ASP 297 606 606 ASP ASP B . n 
A 1 298 TYR 298 607 607 TYR TYR B . n 
A 1 299 ALA 299 608 608 ALA ALA B . n 
A 1 300 LEU 300 609 609 LEU LEU B . n 
A 1 301 ILE 301 610 610 ILE ILE B . n 
A 1 302 ALA 302 611 611 ALA ALA B . n 
A 1 303 ILE 303 612 612 ILE ILE B . n 
A 1 304 GLY 304 613 613 GLY GLY B . n 
A 1 305 ARG 305 614 614 ARG ARG B . n 
A 1 306 TYR 306 615 615 TYR TYR B . n 
A 1 307 SER 307 616 616 SER SER B . n 
A 1 308 MET 308 617 617 MET MET B . n 
A 1 309 THR 309 618 618 THR THR B . n 
A 1 310 ILE 310 619 619 ILE ILE B . n 
A 1 311 GLU 311 620 620 GLU GLU B . n 
A 1 312 THR 312 621 621 THR THR B . n 
A 1 313 VAL 313 622 622 VAL VAL B . n 
A 1 314 ASP 314 623 623 ASP ASP B . n 
A 1 315 VAL 315 624 624 VAL VAL B . n 
A 1 316 GLY 316 625 625 GLY GLY B . n 
A 1 317 TRP 317 626 626 TRP TRP B . n 
A 1 318 CYS 318 627 627 CYS CYS B . n 
A 1 319 LYS 319 628 628 LYS LYS B . n 
A 1 320 GLU 320 629 629 GLU GLU B . n 
A 1 321 ILE 321 630 630 ILE ILE B . n 
A 1 322 THR 322 631 631 THR THR B . n 
A 1 323 ASP 323 632 632 ASP ASP B . n 
A 1 324 GLN 324 633 633 GLN GLN B . n 
A 1 325 GLY 325 634 634 GLY GLY B . n 
A 1 326 ALA 326 635 635 ALA ALA B . n 
A 1 327 THR 327 636 636 THR THR B . n 
A 1 328 LEU 328 637 637 LEU LEU B . n 
A 1 329 ILE 329 638 638 ILE ILE B . n 
A 1 330 ALA 330 639 639 ALA ALA B . n 
A 1 331 GLN 331 640 640 GLN GLN B . n 
A 1 332 SER 332 641 641 SER SER B . n 
A 1 333 SER 333 642 642 SER SER B . n 
A 1 334 LYS 334 643 643 LYS LYS B . n 
A 1 335 SER 335 644 644 SER SER B . n 
A 1 336 LEU 336 645 645 LEU LEU B . n 
A 1 337 ARG 337 646 646 ARG ARG B . n 
A 1 338 TYR 338 647 647 TYR TYR B . n 
A 1 339 LEU 339 648 648 LEU LEU B . n 
A 1 340 GLY 340 649 649 GLY GLY B . n 
A 1 341 LEU 341 650 650 LEU LEU B . n 
A 1 342 MET 342 651 651 MET MET B . n 
A 1 343 ARG 343 652 652 ARG ARG B . n 
A 1 344 CYS 344 653 653 CYS CYS B . n 
A 1 345 ASP 345 654 654 ASP ASP B . n 
A 1 346 LYS 346 655 655 LYS LYS B . n 
A 1 347 VAL 347 656 656 VAL VAL B . n 
A 1 348 ASN 348 657 657 ASN ASN B . n 
A 1 349 GLU 349 658 658 GLU GLU B . n 
A 1 350 VAL 350 659 659 VAL VAL B . n 
A 1 351 THR 351 660 660 THR THR B . n 
A 1 352 VAL 352 661 661 VAL VAL B . n 
A 1 353 GLU 353 662 662 GLU GLU B . n 
A 1 354 GLN 354 663 663 GLN GLN B . n 
A 1 355 LEU 355 664 664 LEU LEU B . n 
A 1 356 VAL 356 665 665 VAL VAL B . n 
A 1 357 GLN 357 666 666 GLN GLN B . n 
A 1 358 GLN 358 667 667 GLN GLN B . n 
A 1 359 TYR 359 668 668 TYR TYR B . n 
A 1 360 PRO 360 669 669 PRO PRO B . n 
A 1 361 HIS 361 670 670 HIS HIS B . n 
A 1 362 ILE 362 671 671 ILE ILE B . n 
A 1 363 THR 363 672 672 THR THR B . n 
A 1 364 PHE 364 673 673 PHE PHE B . n 
A 1 365 SER 365 674 674 SER SER B . n 
A 1 366 THR 366 675 675 THR THR B . n 
A 1 367 VAL 367 676 676 VAL VAL B . n 
A 1 368 LEU 368 677 677 LEU LEU B . n 
A 1 369 GLN 369 678 678 GLN GLN B . n 
A 1 370 ASP 370 679 679 ASP ASP B . n 
A 1 371 CYS 371 680 680 CYS CYS B . n 
A 1 372 LYS 372 681 681 LYS LYS B . n 
A 1 373 ARG 373 682 682 ARG ARG B . n 
A 1 374 THR 374 683 683 THR THR B . n 
A 1 375 LEU 375 684 684 LEU LEU B . n 
A 1 376 GLU 376 685 685 GLU GLU B . n 
A 1 377 ARG 377 686 686 ARG ARG B . n 
A 1 378 ALA 378 687 ?   ?   ?   B . n 
A 1 379 TYR 379 688 ?   ?   ?   B . n 
A 1 380 GLN 380 689 ?   ?   ?   B . n 
A 1 381 MET 381 690 ?   ?   ?   B . n 
A 1 382 GLY 382 691 ?   ?   ?   B . n 
A 1 383 TRP 383 692 ?   ?   ?   B . n 
A 1 384 THR 384 693 ?   ?   ?   B . n 
A 1 385 PRO 385 694 ?   ?   ?   B . n 
A 1 386 ASN 386 695 ?   ?   ?   B . n 
A 1 387 MET 387 696 ?   ?   ?   B . n 
A 1 388 SER 388 697 ?   ?   ?   B . n 
A 1 389 ALA 389 698 ?   ?   ?   B . n 
A 1 390 ALA 390 699 ?   ?   ?   B . n 
A 1 391 SER 391 700 ?   ?   ?   B . n 
A 1 392 SER 392 701 ?   ?   ?   B . n 
B 2 1   SER 1   7   ?   ?   ?   C . n 
B 2 2   VAL 2   8   ?   ?   ?   C . n 
B 2 3   PHE 3   9   ?   ?   ?   C . n 
B 2 4   ALA 4   10  ?   ?   ?   C . n 
B 2 5   TYR 5   11  ?   ?   ?   C . n 
B 2 6   GLU 6   12  ?   ?   ?   C . n 
B 2 7   SER 7   13  ?   ?   ?   C . n 
B 2 8   SER 8   14  ?   ?   ?   C . n 
B 2 9   VAL 9   15  ?   ?   ?   C . n 
B 2 10  HIS 10  16  ?   ?   ?   C . n 
B 2 11  SER 11  17  17  SER SER C . n 
B 2 12  THR 12  18  18  THR THR C . n 
B 2 13  ASN 13  19  19  ASN ASN C . n 
B 2 14  VAL 14  20  20  VAL VAL C . n 
B 2 15  LEU 15  21  21  LEU LEU C . n 
B 2 16  LEU 16  22  22  LEU LEU C . n 
B 2 17  SER 17  23  23  SER SER C . n 
B 2 18  LEU 18  24  24  LEU LEU C . n 
B 2 19  ASN 19  25  25  ASN ASN C . n 
B 2 20  ASP 20  26  26  ASP ASP C . n 
B 2 21  GLN 21  27  27  GLN GLN C . n 
B 2 22  ARG 22  28  28  ARG ARG C . n 
B 2 23  LYS 23  29  29  LYS LYS C . n 
B 2 24  LYS 24  30  30  LYS LYS C . n 
B 2 25  ASP 25  31  31  ASP ASP C . n 
B 2 26  VAL 26  32  32  VAL VAL C . n 
B 2 27  LEU 27  33  33  LEU LEU C . n 
B 2 28  CYS 28  34  34  CYS CYS C . n 
B 2 29  ASP 29  35  35  ASP ASP C . n 
B 2 30  VAL 30  36  36  VAL VAL C . n 
B 2 31  THR 31  37  37  THR THR C . n 
B 2 32  ILE 32  38  38  ILE ILE C . n 
B 2 33  PHE 33  39  39  PHE PHE C . n 
B 2 34  VAL 34  40  40  VAL VAL C . n 
B 2 35  GLU 35  41  41  GLU GLU C . n 
B 2 36  GLY 36  42  42  GLY GLY C . n 
B 2 37  GLN 37  43  43  GLN GLN C . n 
B 2 38  ARG 38  44  44  ARG ARG C . n 
B 2 39  PHE 39  45  45  PHE PHE C . n 
B 2 40  ARG 40  46  46  ARG ARG C . n 
B 2 41  ALA 41  47  47  ALA ALA C . n 
B 2 42  HIS 42  48  48  HIS HIS C . n 
B 2 43  ARG 43  49  49  ARG ARG C . n 
B 2 44  SER 44  50  50  SER SER C . n 
B 2 45  VAL 45  51  51  VAL VAL C . n 
B 2 46  LEU 46  52  52  LEU LEU C . n 
B 2 47  ALA 47  53  53  ALA ALA C . n 
B 2 48  ALA 48  54  54  ALA ALA C . n 
B 2 49  CYS 49  55  55  CYS CYS C . n 
B 2 50  SER 50  56  56  SER SER C . n 
B 2 51  SER 51  57  57  SER SER C . n 
B 2 52  TYR 52  58  58  TYR TYR C . n 
B 2 53  PHE 53  59  59  PHE PHE C . n 
B 2 54  HIS 54  60  60  HIS HIS C . n 
B 2 55  SER 55  61  61  SER SER C . n 
B 2 56  ARG 56  62  62  ARG ARG C . n 
B 2 57  ILE 57  63  63  ILE ILE C . n 
B 2 58  VAL 58  64  64  VAL VAL C . n 
B 2 59  GLY 59  65  65  GLY GLY C . n 
B 2 60  GLN 60  66  66  GLN GLN C . n 
B 2 61  ALA 61  67  67  ALA ALA C . n 
B 2 62  ASP 62  68  68  ASP ASP C . n 
B 2 63  GLY 63  69  69  GLY GLY C . n 
B 2 64  GLU 64  70  70  GLU GLU C . n 
B 2 65  LEU 65  71  71  LEU LEU C . n 
B 2 66  ASN 66  72  72  ASN ASN C . n 
B 2 67  ILE 67  73  73  ILE ILE C . n 
B 2 68  THR 68  74  74  THR THR C . n 
B 2 69  LEU 69  75  75  LEU LEU C . n 
B 2 70  PRO 70  76  76  PRO PRO C . n 
B 2 71  GLU 71  77  77  GLU GLU C . n 
B 2 72  GLU 72  78  78  GLU GLU C . n 
B 2 73  VAL 73  79  79  VAL VAL C . n 
B 2 74  THR 74  80  80  THR THR C . n 
B 2 75  VAL 75  81  81  VAL VAL C . n 
B 2 76  LYS 76  82  82  LYS LYS C . n 
B 2 77  GLY 77  83  83  GLY GLY C . n 
B 2 78  PHE 78  84  84  PHE PHE C . n 
B 2 79  GLU 79  85  85  GLU GLU C . n 
B 2 80  PRO 80  86  86  PRO PRO C . n 
B 2 81  LEU 81  87  87  LEU LEU C . n 
B 2 82  ILE 82  88  88  ILE ILE C . n 
B 2 83  GLN 83  89  89  GLN GLN C . n 
B 2 84  PHE 84  90  90  PHE PHE C . n 
B 2 85  ALA 85  91  91  ALA ALA C . n 
B 2 86  TYR 86  92  92  TYR TYR C . n 
B 2 87  THR 87  93  93  THR THR C . n 
B 2 88  ALA 88  94  94  ALA ALA C . n 
B 2 89  LYS 89  95  95  LYS LYS C . n 
B 2 90  LEU 90  96  96  LEU LEU C . n 
B 2 91  ILE 91  97  97  ILE ILE C . n 
B 2 92  LEU 92  98  98  LEU LEU C . n 
B 2 93  SER 93  99  99  SER SER C . n 
B 2 94  LYS 94  100 100 LYS LYS C . n 
B 2 95  GLU 95  101 101 GLU GLU C . n 
B 2 96  ASN 96  102 102 ASN ASN C . n 
B 2 97  VAL 97  103 103 VAL VAL C . n 
B 2 98  ASP 98  104 104 ASP ASP C . n 
B 2 99  GLU 99  105 105 GLU GLU C . n 
B 2 100 VAL 100 106 106 VAL VAL C . n 
B 2 101 CYS 101 107 107 CYS CYS C . n 
B 2 102 LYS 102 108 108 LYS LYS C . n 
B 2 103 CYS 103 109 109 CYS CYS C . n 
B 2 104 VAL 104 110 110 VAL VAL C . n 
B 2 105 GLU 105 111 111 GLU GLU C . n 
B 2 106 PHE 106 112 112 PHE PHE C . n 
B 2 107 LEU 107 113 113 LEU LEU C . n 
B 2 108 SER 108 114 114 SER SER C . n 
B 2 109 VAL 109 115 115 VAL VAL C . n 
B 2 110 HIS 110 116 116 HIS HIS C . n 
B 2 111 ASN 111 117 117 ASN ASN C . n 
B 2 112 ILE 112 118 118 ILE ILE C . n 
B 2 113 GLU 113 119 ?   ?   ?   C . n 
B 2 114 GLU 114 120 ?   ?   ?   C . n 
B 2 115 SER 115 121 ?   ?   ?   C . n 
B 2 116 CYS 116 122 ?   ?   ?   C . n 
B 2 117 PHE 117 123 ?   ?   ?   C . n 
B 2 118 GLN 118 124 ?   ?   ?   C . n 
B 2 119 PHE 119 125 ?   ?   ?   C . n 
B 2 120 LEU 120 126 ?   ?   ?   C . n 
B 2 121 LYS 121 127 ?   ?   ?   C . n 
B 2 122 PHE 122 128 ?   ?   ?   C . n 
C 1 1   CYS 1   310 ?   ?   ?   H . n 
C 1 2   HIS 2   311 ?   ?   ?   H . n 
C 1 3   ARG 3   312 ?   ?   ?   H . n 
C 1 4   GLU 4   313 ?   ?   ?   H . n 
C 1 5   PRO 5   314 ?   ?   ?   H . n 
C 1 6   PRO 6   315 ?   ?   ?   H . n 
C 1 7   PRO 7   316 ?   ?   ?   H . n 
C 1 8   GLU 8   317 ?   ?   ?   H . n 
C 1 9   THR 9   318 ?   ?   ?   H . n 
C 1 10  PRO 10  319 ?   ?   ?   H . n 
C 1 11  ASP 11  320 ?   ?   ?   H . n 
C 1 12  ILE 12  321 ?   ?   ?   H . n 
C 1 13  ASN 13  322 ?   ?   ?   H . n 
C 1 14  GLN 14  323 ?   ?   ?   H . n 
C 1 15  LEU 15  324 ?   ?   ?   H . n 
C 1 16  PRO 16  325 ?   ?   ?   H . n 
C 1 17  PRO 17  326 ?   ?   ?   H . n 
C 1 18  SER 18  327 ?   ?   ?   H . n 
C 1 19  ILE 19  328 ?   ?   ?   H . n 
C 1 20  LEU 20  329 ?   ?   ?   H . n 
C 1 21  LEU 21  330 ?   ?   ?   H . n 
C 1 22  LYS 22  331 ?   ?   ?   H . n 
C 1 23  ILE 23  332 ?   ?   ?   H . n 
C 1 24  PHE 24  333 ?   ?   ?   H . n 
C 1 25  SER 25  334 ?   ?   ?   H . n 
C 1 26  ASN 26  335 ?   ?   ?   H . n 
C 1 27  LEU 27  336 ?   ?   ?   H . n 
C 1 28  SER 28  337 ?   ?   ?   H . n 
C 1 29  LEU 29  338 ?   ?   ?   H . n 
C 1 30  ASP 30  339 ?   ?   ?   H . n 
C 1 31  GLU 31  340 ?   ?   ?   H . n 
C 1 32  ARG 32  341 ?   ?   ?   H . n 
C 1 33  CYS 33  342 ?   ?   ?   H . n 
C 1 34  LEU 34  343 ?   ?   ?   H . n 
C 1 35  SER 35  344 ?   ?   ?   H . n 
C 1 36  ALA 36  345 ?   ?   ?   H . n 
C 1 37  SER 37  346 ?   ?   ?   H . n 
C 1 38  LEU 38  347 ?   ?   ?   H . n 
C 1 39  VAL 39  348 ?   ?   ?   H . n 
C 1 40  CYS 40  349 ?   ?   ?   H . n 
C 1 41  LYS 41  350 ?   ?   ?   H . n 
C 1 42  TYR 42  351 ?   ?   ?   H . n 
C 1 43  TRP 43  352 ?   ?   ?   H . n 
C 1 44  ARG 44  353 ?   ?   ?   H . n 
C 1 45  ASP 45  354 ?   ?   ?   H . n 
C 1 46  LEU 46  355 ?   ?   ?   H . n 
C 1 47  CYS 47  356 ?   ?   ?   H . n 
C 1 48  LEU 48  357 ?   ?   ?   H . n 
C 1 49  ASP 49  358 ?   ?   ?   H . n 
C 1 50  PHE 50  359 ?   ?   ?   H . n 
C 1 51  GLN 51  360 ?   ?   ?   H . n 
C 1 52  PHE 52  361 ?   ?   ?   H . n 
C 1 53  TRP 53  362 ?   ?   ?   H . n 
C 1 54  LYS 54  363 363 LYS LYS H . n 
C 1 55  GLN 55  364 364 GLN GLN H . n 
C 1 56  LEU 56  365 365 LEU LEU H . n 
C 1 57  ASP 57  366 366 ASP ASP H . n 
C 1 58  LEU 58  367 367 LEU LEU H . n 
C 1 59  SER 59  368 368 SER SER H . n 
C 1 60  SER 60  369 369 SER SER H . n 
C 1 61  ARG 61  370 370 ARG ARG H . n 
C 1 62  GLN 62  371 371 GLN GLN H . n 
C 1 63  GLN 63  372 372 GLN GLN H . n 
C 1 64  VAL 64  373 373 VAL VAL H . n 
C 1 65  THR 65  374 374 THR THR H . n 
C 1 66  ASP 66  375 375 ASP ASP H . n 
C 1 67  GLU 67  376 376 GLU GLU H . n 
C 1 68  LEU 68  377 377 LEU LEU H . n 
C 1 69  LEU 69  378 378 LEU LEU H . n 
C 1 70  GLU 70  379 379 GLU GLU H . n 
C 1 71  LYS 71  380 380 LYS LYS H . n 
C 1 72  ILE 72  381 381 ILE ILE H . n 
C 1 73  ALA 73  382 382 ALA ALA H . n 
C 1 74  SER 74  383 383 SER SER H . n 
C 1 75  ARG 75  384 384 ARG ARG H . n 
C 1 76  SER 76  385 385 SER SER H . n 
C 1 77  GLN 77  386 386 GLN GLN H . n 
C 1 78  ASN 78  387 387 ASN ASN H . n 
C 1 79  ILE 79  388 388 ILE ILE H . n 
C 1 80  ILE 80  389 389 ILE ILE H . n 
C 1 81  GLU 81  390 390 GLU GLU H . n 
C 1 82  ILE 82  391 391 ILE ILE H . n 
C 1 83  ASN 83  392 392 ASN ASN H . n 
C 1 84  ILE 84  393 393 ILE ILE H . n 
C 1 85  SER 85  394 394 SER SER H . n 
C 1 86  ASP 86  395 395 ASP ASP H . n 
C 1 87  CYS 87  396 396 CYS CYS H . n 
C 1 88  ARG 88  397 397 ARG ARG H . n 
C 1 89  SER 89  398 398 SER SER H . n 
C 1 90  MET 90  399 399 MET MET H . n 
C 1 91  SER 91  400 400 SER SER H . n 
C 1 92  ASP 92  401 401 ASP ASP H . n 
C 1 93  ASN 93  402 402 ASN ASN H . n 
C 1 94  GLY 94  403 403 GLY GLY H . n 
C 1 95  VAL 95  404 404 VAL VAL H . n 
C 1 96  CYS 96  405 405 CYS CYS H . n 
C 1 97  VAL 97  406 406 VAL VAL H . n 
C 1 98  LEU 98  407 407 LEU LEU H . n 
C 1 99  ALA 99  408 408 ALA ALA H . n 
C 1 100 PHE 100 409 409 PHE PHE H . n 
C 1 101 LYS 101 410 410 LYS LYS H . n 
C 1 102 CYS 102 411 411 CYS CYS H . n 
C 1 103 PRO 103 412 412 PRO PRO H . n 
C 1 104 GLY 104 413 413 GLY GLY H . n 
C 1 105 LEU 105 414 414 LEU LEU H . n 
C 1 106 LEU 106 415 415 LEU LEU H . n 
C 1 107 ARG 107 416 416 ARG ARG H . n 
C 1 108 TYR 108 417 417 TYR TYR H . n 
C 1 109 THR 109 418 418 THR THR H . n 
C 1 110 ALA 110 419 419 ALA ALA H . n 
C 1 111 TYR 111 420 420 TYR TYR H . n 
C 1 112 ARG 112 421 421 ARG ARG H . n 
C 1 113 CYS 113 422 422 CYS CYS H . n 
C 1 114 LYS 114 423 423 LYS LYS H . n 
C 1 115 GLN 115 424 424 GLN GLN H . n 
C 1 116 LEU 116 425 425 LEU LEU H . n 
C 1 117 SER 117 426 426 SER SER H . n 
C 1 118 ASP 118 427 427 ASP ASP H . n 
C 1 119 THR 119 428 428 THR THR H . n 
C 1 120 SER 120 429 429 SER SER H . n 
C 1 121 ILE 121 430 430 ILE ILE H . n 
C 1 122 ILE 122 431 431 ILE ILE H . n 
C 1 123 ALA 123 432 432 ALA ALA H . n 
C 1 124 VAL 124 433 433 VAL VAL H . n 
C 1 125 ALA 125 434 434 ALA ALA H . n 
C 1 126 SER 126 435 435 SER SER H . n 
C 1 127 HIS 127 436 436 HIS HIS H . n 
C 1 128 CYS 128 437 437 CYS CYS H . n 
C 1 129 PRO 129 438 438 PRO PRO H . n 
C 1 130 LEU 130 439 439 LEU LEU H . n 
C 1 131 LEU 131 440 440 LEU LEU H . n 
C 1 132 GLN 132 441 441 GLN GLN H . n 
C 1 133 LYS 133 442 442 LYS LYS H . n 
C 1 134 VAL 134 443 443 VAL VAL H . n 
C 1 135 HIS 135 444 444 HIS HIS H . n 
C 1 136 VAL 136 445 445 VAL VAL H . n 
C 1 137 GLY 137 446 446 GLY GLY H . n 
C 1 138 ASN 138 447 447 ASN ASN H . n 
C 1 139 GLN 139 448 448 GLN GLN H . n 
C 1 140 ASP 140 449 449 ASP ASP H . n 
C 1 141 LYS 141 450 450 LYS LYS H . n 
C 1 142 LEU 142 451 451 LEU LEU H . n 
C 1 143 THR 143 452 452 THR THR H . n 
C 1 144 ASP 144 453 453 ASP ASP H . n 
C 1 145 GLU 145 454 454 GLU GLU H . n 
C 1 146 GLY 146 455 455 GLY GLY H . n 
C 1 147 LEU 147 456 456 LEU LEU H . n 
C 1 148 LYS 148 457 457 LYS LYS H . n 
C 1 149 GLN 149 458 458 GLN GLN H . n 
C 1 150 LEU 150 459 459 LEU LEU H . n 
C 1 151 GLY 151 460 460 GLY GLY H . n 
C 1 152 SER 152 461 461 SER SER H . n 
C 1 153 LYS 153 462 462 LYS LYS H . n 
C 1 154 CYS 154 463 463 CYS CYS H . n 
C 1 155 ARG 155 464 464 ARG ARG H . n 
C 1 156 GLU 156 465 465 GLU GLU H . n 
C 1 157 LEU 157 466 466 LEU LEU H . n 
C 1 158 LYS 158 467 467 LYS LYS H . n 
C 1 159 ASP 159 468 468 ASP ASP H . n 
C 1 160 ILE 160 469 469 ILE ILE H . n 
C 1 161 HIS 161 470 470 HIS HIS H . n 
C 1 162 PHE 162 471 471 PHE PHE H . n 
C 1 163 GLY 163 472 472 GLY GLY H . n 
C 1 164 GLN 164 473 473 GLN GLN H . n 
C 1 165 CYS 165 474 474 CYS CYS H . n 
C 1 166 TYR 166 475 475 TYR TYR H . n 
C 1 167 LYS 167 476 476 LYS LYS H . n 
C 1 168 ILE 168 477 477 ILE ILE H . n 
C 1 169 SER 169 478 478 SER SER H . n 
C 1 170 ASP 170 479 479 ASP ASP H . n 
C 1 171 GLU 171 480 480 GLU GLU H . n 
C 1 172 GLY 172 481 481 GLY GLY H . n 
C 1 173 MET 173 482 482 MET MET H . n 
C 1 174 ILE 174 483 483 ILE ILE H . n 
C 1 175 VAL 175 484 484 VAL VAL H . n 
C 1 176 ILE 176 485 485 ILE ILE H . n 
C 1 177 ALA 177 486 486 ALA ALA H . n 
C 1 178 LYS 178 487 487 LYS LYS H . n 
C 1 179 GLY 179 488 488 GLY GLY H . n 
C 1 180 CYS 180 489 489 CYS CYS H . n 
C 1 181 LEU 181 490 490 LEU LEU H . n 
C 1 182 LYS 182 491 491 LYS LYS H . n 
C 1 183 LEU 183 492 492 LEU LEU H . n 
C 1 184 GLN 184 493 493 GLN GLN H . n 
C 1 185 ARG 185 494 494 ARG ARG H . n 
C 1 186 ILE 186 495 495 ILE ILE H . n 
C 1 187 TYR 187 496 496 TYR TYR H . n 
C 1 188 MET 188 497 497 MET MET H . n 
C 1 189 GLN 189 498 498 GLN GLN H . n 
C 1 190 GLU 190 499 499 GLU GLU H . n 
C 1 191 ASN 191 500 500 ASN ASN H . n 
C 1 192 LYS 192 501 501 LYS LYS H . n 
C 1 193 LEU 193 502 502 LEU LEU H . n 
C 1 194 VAL 194 503 503 VAL VAL H . n 
C 1 195 THR 195 504 504 THR THR H . n 
C 1 196 ASP 196 505 505 ASP ASP H . n 
C 1 197 GLN 197 506 506 GLN GLN H . n 
C 1 198 SER 198 507 507 SER SER H . n 
C 1 199 VAL 199 508 508 VAL VAL H . n 
C 1 200 LYS 200 509 509 LYS LYS H . n 
C 1 201 ALA 201 510 510 ALA ALA H . n 
C 1 202 PHE 202 511 511 PHE PHE H . n 
C 1 203 ALA 203 512 512 ALA ALA H . n 
C 1 204 GLU 204 513 513 GLU GLU H . n 
C 1 205 HIS 205 514 514 HIS HIS H . n 
C 1 206 CYS 206 515 515 CYS CYS H . n 
C 1 207 PRO 207 516 516 PRO PRO H . n 
C 1 208 GLU 208 517 517 GLU GLU H . n 
C 1 209 LEU 209 518 518 LEU LEU H . n 
C 1 210 GLN 210 519 519 GLN GLN H . n 
C 1 211 TYR 211 520 520 TYR TYR H . n 
C 1 212 VAL 212 521 521 VAL VAL H . n 
C 1 213 GLY 213 522 522 GLY GLY H . n 
C 1 214 PHE 214 523 523 PHE PHE H . n 
C 1 215 MET 215 524 524 MET MET H . n 
C 1 216 GLY 216 525 525 GLY GLY H . n 
C 1 217 CYS 217 526 526 CYS CYS H . n 
C 1 218 SER 218 527 527 SER SER H . n 
C 1 219 VAL 219 528 528 VAL VAL H . n 
C 1 220 THR 220 529 529 THR THR H . n 
C 1 221 SER 221 530 530 SER SER H . n 
C 1 222 LYS 222 531 531 LYS LYS H . n 
C 1 223 GLY 223 532 532 GLY GLY H . n 
C 1 224 VAL 224 533 533 VAL VAL H . n 
C 1 225 ILE 225 534 534 ILE ILE H . n 
C 1 226 HIS 226 535 535 HIS HIS H . n 
C 1 227 LEU 227 536 536 LEU LEU H . n 
C 1 228 THR 228 537 537 THR THR H . n 
C 1 229 LYS 229 538 538 LYS LYS H . n 
C 1 230 LEU 230 539 539 LEU LEU H . n 
C 1 231 ARG 231 540 540 ARG ARG H . n 
C 1 232 ASN 232 541 541 ASN ASN H . n 
C 1 233 LEU 233 542 542 LEU LEU H . n 
C 1 234 SER 234 543 543 SER SER H . n 
C 1 235 SER 235 544 544 SER SER H . n 
C 1 236 LEU 236 545 545 LEU LEU H . n 
C 1 237 ASP 237 546 546 ASP ASP H . n 
C 1 238 LEU 238 547 547 LEU LEU H . n 
C 1 239 ARG 239 548 548 ARG ARG H . n 
C 1 240 HIS 240 549 549 HIS HIS H . n 
C 1 241 ILE 241 550 550 ILE ILE H . n 
C 1 242 THR 242 551 551 THR THR H . n 
C 1 243 GLU 243 552 552 GLU GLU H . n 
C 1 244 LEU 244 553 553 LEU LEU H . n 
C 1 245 ASP 245 554 554 ASP ASP H . n 
C 1 246 ASN 246 555 555 ASN ASN H . n 
C 1 247 GLU 247 556 556 GLU GLU H . n 
C 1 248 THR 248 557 557 THR THR H . n 
C 1 249 VAL 249 558 558 VAL VAL H . n 
C 1 250 MET 250 559 559 MET MET H . n 
C 1 251 GLU 251 560 560 GLU GLU H . n 
C 1 252 ILE 252 561 561 ILE ILE H . n 
C 1 253 VAL 253 562 562 VAL VAL H . n 
C 1 254 LYS 254 563 563 LYS LYS H . n 
C 1 255 ARG 255 564 564 ARG ARG H . n 
C 1 256 CYS 256 565 565 CYS CYS H . n 
C 1 257 LYS 257 566 566 LYS LYS H . n 
C 1 258 ASN 258 567 567 ASN ASN H . n 
C 1 259 LEU 259 568 568 LEU LEU H . n 
C 1 260 SER 260 569 569 SER SER H . n 
C 1 261 SER 261 570 570 SER SER H . n 
C 1 262 LEU 262 571 571 LEU LEU H . n 
C 1 263 ASN 263 572 572 ASN ASN H . n 
C 1 264 LEU 264 573 573 LEU LEU H . n 
C 1 265 CYS 265 574 574 CYS CYS H . n 
C 1 266 LEU 266 575 575 LEU LEU H . n 
C 1 267 ASN 267 576 576 ASN ASN H . n 
C 1 268 TRP 268 577 577 TRP TRP H . n 
C 1 269 ILE 269 578 578 ILE ILE H . n 
C 1 270 ILE 270 579 579 ILE ILE H . n 
C 1 271 ASN 271 580 580 ASN ASN H . n 
C 1 272 ASP 272 581 581 ASP ASP H . n 
C 1 273 ARG 273 582 582 ARG ARG H . n 
C 1 274 CYS 274 583 583 CYS CYS H . n 
C 1 275 VAL 275 584 584 VAL VAL H . n 
C 1 276 GLU 276 585 585 GLU GLU H . n 
C 1 277 VAL 277 586 586 VAL VAL H . n 
C 1 278 ILE 278 587 587 ILE ILE H . n 
C 1 279 ALA 279 588 588 ALA ALA H . n 
C 1 280 LYS 280 589 589 LYS LYS H . n 
C 1 281 GLU 281 590 590 GLU GLU H . n 
C 1 282 GLY 282 591 591 GLY GLY H . n 
C 1 283 GLN 283 592 592 GLN GLN H . n 
C 1 284 ASN 284 593 593 ASN ASN H . n 
C 1 285 LEU 285 594 594 LEU LEU H . n 
C 1 286 LYS 286 595 595 LYS LYS H . n 
C 1 287 GLU 287 596 596 GLU GLU H . n 
C 1 288 LEU 288 597 597 LEU LEU H . n 
C 1 289 TYR 289 598 598 TYR TYR H . n 
C 1 290 LEU 290 599 599 LEU LEU H . n 
C 1 291 VAL 291 600 600 VAL VAL H . n 
C 1 292 SER 292 601 601 SER SER H . n 
C 1 293 CYS 293 602 602 CYS CYS H . n 
C 1 294 LYS 294 603 603 LYS LYS H . n 
C 1 295 ILE 295 604 604 ILE ILE H . n 
C 1 296 THR 296 605 605 THR THR H . n 
C 1 297 ASP 297 606 606 ASP ASP H . n 
C 1 298 TYR 298 607 607 TYR TYR H . n 
C 1 299 ALA 299 608 608 ALA ALA H . n 
C 1 300 LEU 300 609 609 LEU LEU H . n 
C 1 301 ILE 301 610 610 ILE ILE H . n 
C 1 302 ALA 302 611 611 ALA ALA H . n 
C 1 303 ILE 303 612 612 ILE ILE H . n 
C 1 304 GLY 304 613 613 GLY GLY H . n 
C 1 305 ARG 305 614 614 ARG ARG H . n 
C 1 306 TYR 306 615 615 TYR TYR H . n 
C 1 307 SER 307 616 616 SER SER H . n 
C 1 308 MET 308 617 617 MET MET H . n 
C 1 309 THR 309 618 618 THR THR H . n 
C 1 310 ILE 310 619 619 ILE ILE H . n 
C 1 311 GLU 311 620 620 GLU GLU H . n 
C 1 312 THR 312 621 621 THR THR H . n 
C 1 313 VAL 313 622 622 VAL VAL H . n 
C 1 314 ASP 314 623 623 ASP ASP H . n 
C 1 315 VAL 315 624 624 VAL VAL H . n 
C 1 316 GLY 316 625 625 GLY GLY H . n 
C 1 317 TRP 317 626 626 TRP TRP H . n 
C 1 318 CYS 318 627 627 CYS CYS H . n 
C 1 319 LYS 319 628 628 LYS LYS H . n 
C 1 320 GLU 320 629 629 GLU GLU H . n 
C 1 321 ILE 321 630 630 ILE ILE H . n 
C 1 322 THR 322 631 631 THR THR H . n 
C 1 323 ASP 323 632 632 ASP ASP H . n 
C 1 324 GLN 324 633 633 GLN GLN H . n 
C 1 325 GLY 325 634 634 GLY GLY H . n 
C 1 326 ALA 326 635 635 ALA ALA H . n 
C 1 327 THR 327 636 636 THR THR H . n 
C 1 328 LEU 328 637 637 LEU LEU H . n 
C 1 329 ILE 329 638 638 ILE ILE H . n 
C 1 330 ALA 330 639 639 ALA ALA H . n 
C 1 331 GLN 331 640 640 GLN GLN H . n 
C 1 332 SER 332 641 641 SER SER H . n 
C 1 333 SER 333 642 642 SER SER H . n 
C 1 334 LYS 334 643 643 LYS LYS H . n 
C 1 335 SER 335 644 644 SER SER H . n 
C 1 336 LEU 336 645 645 LEU LEU H . n 
C 1 337 ARG 337 646 646 ARG ARG H . n 
C 1 338 TYR 338 647 647 TYR TYR H . n 
C 1 339 LEU 339 648 648 LEU LEU H . n 
C 1 340 GLY 340 649 649 GLY GLY H . n 
C 1 341 LEU 341 650 650 LEU LEU H . n 
C 1 342 MET 342 651 651 MET MET H . n 
C 1 343 ARG 343 652 652 ARG ARG H . n 
C 1 344 CYS 344 653 653 CYS CYS H . n 
C 1 345 ASP 345 654 654 ASP ASP H . n 
C 1 346 LYS 346 655 655 LYS LYS H . n 
C 1 347 VAL 347 656 656 VAL VAL H . n 
C 1 348 ASN 348 657 657 ASN ASN H . n 
C 1 349 GLU 349 658 658 GLU GLU H . n 
C 1 350 VAL 350 659 659 VAL VAL H . n 
C 1 351 THR 351 660 660 THR THR H . n 
C 1 352 VAL 352 661 661 VAL VAL H . n 
C 1 353 GLU 353 662 662 GLU GLU H . n 
C 1 354 GLN 354 663 663 GLN GLN H . n 
C 1 355 LEU 355 664 664 LEU LEU H . n 
C 1 356 VAL 356 665 665 VAL VAL H . n 
C 1 357 GLN 357 666 666 GLN GLN H . n 
C 1 358 GLN 358 667 667 GLN GLN H . n 
C 1 359 TYR 359 668 668 TYR TYR H . n 
C 1 360 PRO 360 669 669 PRO PRO H . n 
C 1 361 HIS 361 670 670 HIS HIS H . n 
C 1 362 ILE 362 671 671 ILE ILE H . n 
C 1 363 THR 363 672 672 THR THR H . n 
C 1 364 PHE 364 673 673 PHE PHE H . n 
C 1 365 SER 365 674 674 SER SER H . n 
C 1 366 THR 366 675 675 THR THR H . n 
C 1 367 VAL 367 676 676 VAL VAL H . n 
C 1 368 LEU 368 677 677 LEU LEU H . n 
C 1 369 GLN 369 678 678 GLN GLN H . n 
C 1 370 ASP 370 679 679 ASP ASP H . n 
C 1 371 CYS 371 680 680 CYS CYS H . n 
C 1 372 LYS 372 681 681 LYS LYS H . n 
C 1 373 ARG 373 682 682 ARG ARG H . n 
C 1 374 THR 374 683 683 THR THR H . n 
C 1 375 LEU 375 684 684 LEU LEU H . n 
C 1 376 GLU 376 685 685 GLU GLU H . n 
C 1 377 ARG 377 686 ?   ?   ?   H . n 
C 1 378 ALA 378 687 ?   ?   ?   H . n 
C 1 379 TYR 379 688 ?   ?   ?   H . n 
C 1 380 GLN 380 689 ?   ?   ?   H . n 
C 1 381 MET 381 690 ?   ?   ?   H . n 
C 1 382 GLY 382 691 ?   ?   ?   H . n 
C 1 383 TRP 383 692 ?   ?   ?   H . n 
C 1 384 THR 384 693 ?   ?   ?   H . n 
C 1 385 PRO 385 694 ?   ?   ?   H . n 
C 1 386 ASN 386 695 ?   ?   ?   H . n 
C 1 387 MET 387 696 ?   ?   ?   H . n 
C 1 388 SER 388 697 ?   ?   ?   H . n 
C 1 389 ALA 389 698 ?   ?   ?   H . n 
C 1 390 ALA 390 699 ?   ?   ?   H . n 
C 1 391 SER 391 700 ?   ?   ?   H . n 
C 1 392 SER 392 701 ?   ?   ?   H . n 
D 2 1   SER 1   7   ?   ?   ?   I . n 
D 2 2   VAL 2   8   ?   ?   ?   I . n 
D 2 3   PHE 3   9   ?   ?   ?   I . n 
D 2 4   ALA 4   10  ?   ?   ?   I . n 
D 2 5   TYR 5   11  ?   ?   ?   I . n 
D 2 6   GLU 6   12  ?   ?   ?   I . n 
D 2 7   SER 7   13  ?   ?   ?   I . n 
D 2 8   SER 8   14  ?   ?   ?   I . n 
D 2 9   VAL 9   15  ?   ?   ?   I . n 
D 2 10  HIS 10  16  16  HIS HIS I . n 
D 2 11  SER 11  17  17  SER SER I . n 
D 2 12  THR 12  18  18  THR THR I . n 
D 2 13  ASN 13  19  19  ASN ASN I . n 
D 2 14  VAL 14  20  20  VAL VAL I . n 
D 2 15  LEU 15  21  21  LEU LEU I . n 
D 2 16  LEU 16  22  22  LEU LEU I . n 
D 2 17  SER 17  23  23  SER SER I . n 
D 2 18  LEU 18  24  24  LEU LEU I . n 
D 2 19  ASN 19  25  25  ASN ASN I . n 
D 2 20  ASP 20  26  26  ASP ASP I . n 
D 2 21  GLN 21  27  27  GLN GLN I . n 
D 2 22  ARG 22  28  28  ARG ARG I . n 
D 2 23  LYS 23  29  29  LYS LYS I . n 
D 2 24  LYS 24  30  30  LYS LYS I . n 
D 2 25  ASP 25  31  31  ASP ASP I . n 
D 2 26  VAL 26  32  32  VAL VAL I . n 
D 2 27  LEU 27  33  33  LEU LEU I . n 
D 2 28  CYS 28  34  34  CYS CYS I . n 
D 2 29  ASP 29  35  35  ASP ASP I . n 
D 2 30  VAL 30  36  36  VAL VAL I . n 
D 2 31  THR 31  37  37  THR THR I . n 
D 2 32  ILE 32  38  38  ILE ILE I . n 
D 2 33  PHE 33  39  39  PHE PHE I . n 
D 2 34  VAL 34  40  40  VAL VAL I . n 
D 2 35  GLU 35  41  41  GLU GLU I . n 
D 2 36  GLY 36  42  42  GLY GLY I . n 
D 2 37  GLN 37  43  43  GLN GLN I . n 
D 2 38  ARG 38  44  44  ARG ARG I . n 
D 2 39  PHE 39  45  45  PHE PHE I . n 
D 2 40  ARG 40  46  46  ARG ARG I . n 
D 2 41  ALA 41  47  47  ALA ALA I . n 
D 2 42  HIS 42  48  48  HIS HIS I . n 
D 2 43  ARG 43  49  49  ARG ARG I . n 
D 2 44  SER 44  50  50  SER SER I . n 
D 2 45  VAL 45  51  51  VAL VAL I . n 
D 2 46  LEU 46  52  52  LEU LEU I . n 
D 2 47  ALA 47  53  53  ALA ALA I . n 
D 2 48  ALA 48  54  54  ALA ALA I . n 
D 2 49  CYS 49  55  55  CYS CYS I . n 
D 2 50  SER 50  56  56  SER SER I . n 
D 2 51  SER 51  57  57  SER SER I . n 
D 2 52  TYR 52  58  58  TYR TYR I . n 
D 2 53  PHE 53  59  59  PHE PHE I . n 
D 2 54  HIS 54  60  60  HIS HIS I . n 
D 2 55  SER 55  61  61  SER SER I . n 
D 2 56  ARG 56  62  62  ARG ARG I . n 
D 2 57  ILE 57  63  63  ILE ILE I . n 
D 2 58  VAL 58  64  64  VAL VAL I . n 
D 2 59  GLY 59  65  65  GLY GLY I . n 
D 2 60  GLN 60  66  66  GLN GLN I . n 
D 2 61  ALA 61  67  67  ALA ALA I . n 
D 2 62  ASP 62  68  68  ASP ASP I . n 
D 2 63  GLY 63  69  69  GLY GLY I . n 
D 2 64  GLU 64  70  70  GLU GLU I . n 
D 2 65  LEU 65  71  71  LEU LEU I . n 
D 2 66  ASN 66  72  72  ASN ASN I . n 
D 2 67  ILE 67  73  73  ILE ILE I . n 
D 2 68  THR 68  74  74  THR THR I . n 
D 2 69  LEU 69  75  75  LEU LEU I . n 
D 2 70  PRO 70  76  76  PRO PRO I . n 
D 2 71  GLU 71  77  77  GLU GLU I . n 
D 2 72  GLU 72  78  78  GLU GLU I . n 
D 2 73  VAL 73  79  79  VAL VAL I . n 
D 2 74  THR 74  80  80  THR THR I . n 
D 2 75  VAL 75  81  81  VAL VAL I . n 
D 2 76  LYS 76  82  82  LYS LYS I . n 
D 2 77  GLY 77  83  83  GLY GLY I . n 
D 2 78  PHE 78  84  84  PHE PHE I . n 
D 2 79  GLU 79  85  85  GLU GLU I . n 
D 2 80  PRO 80  86  86  PRO PRO I . n 
D 2 81  LEU 81  87  87  LEU LEU I . n 
D 2 82  ILE 82  88  88  ILE ILE I . n 
D 2 83  GLN 83  89  89  GLN GLN I . n 
D 2 84  PHE 84  90  90  PHE PHE I . n 
D 2 85  ALA 85  91  91  ALA ALA I . n 
D 2 86  TYR 86  92  92  TYR TYR I . n 
D 2 87  THR 87  93  93  THR THR I . n 
D 2 88  ALA 88  94  94  ALA ALA I . n 
D 2 89  LYS 89  95  95  LYS LYS I . n 
D 2 90  LEU 90  96  96  LEU LEU I . n 
D 2 91  ILE 91  97  97  ILE ILE I . n 
D 2 92  LEU 92  98  98  LEU LEU I . n 
D 2 93  SER 93  99  99  SER SER I . n 
D 2 94  LYS 94  100 100 LYS LYS I . n 
D 2 95  GLU 95  101 101 GLU GLU I . n 
D 2 96  ASN 96  102 102 ASN ASN I . n 
D 2 97  VAL 97  103 103 VAL VAL I . n 
D 2 98  ASP 98  104 104 ASP ASP I . n 
D 2 99  GLU 99  105 105 GLU GLU I . n 
D 2 100 VAL 100 106 106 VAL VAL I . n 
D 2 101 CYS 101 107 107 CYS CYS I . n 
D 2 102 LYS 102 108 108 LYS LYS I . n 
D 2 103 CYS 103 109 109 CYS CYS I . n 
D 2 104 VAL 104 110 110 VAL VAL I . n 
D 2 105 GLU 105 111 111 GLU GLU I . n 
D 2 106 PHE 106 112 112 PHE PHE I . n 
D 2 107 LEU 107 113 113 LEU LEU I . n 
D 2 108 SER 108 114 114 SER SER I . n 
D 2 109 VAL 109 115 115 VAL VAL I . n 
D 2 110 HIS 110 116 116 HIS HIS I . n 
D 2 111 ASN 111 117 117 ASN ASN I . n 
D 2 112 ILE 112 118 118 ILE ILE I . n 
D 2 113 GLU 113 119 ?   ?   ?   I . n 
D 2 114 GLU 114 120 ?   ?   ?   I . n 
D 2 115 SER 115 121 ?   ?   ?   I . n 
D 2 116 CYS 116 122 ?   ?   ?   I . n 
D 2 117 PHE 117 123 ?   ?   ?   I . n 
D 2 118 GLN 118 124 ?   ?   ?   I . n 
D 2 119 PHE 119 125 ?   ?   ?   I . n 
D 2 120 LEU 120 126 ?   ?   ?   I . n 
D 2 121 LYS 121 127 ?   ?   ?   I . n 
D 2 122 PHE 122 128 ?   ?   ?   I . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 B ARG 370 ? NH1 ? A ARG 61  NH1 
2   1 Y 1 B ARG 370 ? NH2 ? A ARG 61  NH2 
3   1 Y 1 B ARG 384 ? NH1 ? A ARG 75  NH1 
4   1 Y 1 B ARG 384 ? NH2 ? A ARG 75  NH2 
5   1 Y 1 B ARG 397 ? NH1 ? A ARG 88  NH1 
6   1 Y 1 B ARG 397 ? NH2 ? A ARG 88  NH2 
7   1 Y 1 B ARG 416 ? NH1 ? A ARG 107 NH1 
8   1 Y 1 B ARG 416 ? NH2 ? A ARG 107 NH2 
9   1 Y 1 B TYR 417 ? OH  ? A TYR 108 OH  
10  1 Y 1 B TYR 420 ? OH  ? A TYR 111 OH  
11  1 Y 1 B ARG 421 ? NH1 ? A ARG 112 NH1 
12  1 Y 1 B ARG 421 ? NH2 ? A ARG 112 NH2 
13  1 Y 1 B ARG 464 ? NH1 ? A ARG 155 NH1 
14  1 Y 1 B ARG 464 ? NH2 ? A ARG 155 NH2 
15  1 Y 1 B TYR 475 ? OH  ? A TYR 166 OH  
16  1 Y 1 B ARG 494 ? NH1 ? A ARG 185 NH1 
17  1 Y 1 B ARG 494 ? NH2 ? A ARG 185 NH2 
18  1 Y 1 B TYR 496 ? OH  ? A TYR 187 OH  
19  1 Y 1 B TYR 520 ? OH  ? A TYR 211 OH  
20  1 Y 1 B ARG 540 ? NH1 ? A ARG 231 NH1 
21  1 Y 1 B ARG 540 ? NH2 ? A ARG 231 NH2 
22  1 Y 1 B ARG 548 ? NH1 ? A ARG 239 NH1 
23  1 Y 1 B ARG 548 ? NH2 ? A ARG 239 NH2 
24  1 Y 1 B ARG 564 ? NH1 ? A ARG 255 NH1 
25  1 Y 1 B ARG 564 ? NH2 ? A ARG 255 NH2 
26  1 Y 1 B TRP 577 ? CH2 ? A TRP 268 CH2 
27  1 Y 1 B ARG 582 ? NH1 ? A ARG 273 NH1 
28  1 Y 1 B ARG 582 ? NH2 ? A ARG 273 NH2 
29  1 Y 1 B TYR 598 ? OH  ? A TYR 289 OH  
30  1 Y 1 B TYR 607 ? OH  ? A TYR 298 OH  
31  1 Y 1 B ARG 614 ? NH1 ? A ARG 305 NH1 
32  1 Y 1 B ARG 614 ? NH2 ? A ARG 305 NH2 
33  1 Y 1 B TYR 615 ? OH  ? A TYR 306 OH  
34  1 Y 1 B TRP 626 ? CH2 ? A TRP 317 CH2 
35  1 Y 1 B ARG 646 ? NH1 ? A ARG 337 NH1 
36  1 Y 1 B ARG 646 ? NH2 ? A ARG 337 NH2 
37  1 Y 1 B TYR 647 ? OH  ? A TYR 338 OH  
38  1 Y 1 B ARG 652 ? NH1 ? A ARG 343 NH1 
39  1 Y 1 B ARG 652 ? NH2 ? A ARG 343 NH2 
40  1 Y 1 B TYR 668 ? OH  ? A TYR 359 OH  
41  1 Y 1 B ARG 682 ? NH1 ? A ARG 373 NH1 
42  1 Y 1 B ARG 682 ? NH2 ? A ARG 373 NH2 
43  1 Y 1 B ARG 686 ? NH1 ? A ARG 377 NH1 
44  1 Y 1 B ARG 686 ? NH2 ? A ARG 377 NH2 
45  1 Y 1 C ARG 28  ? NH1 ? B ARG 22  NH1 
46  1 Y 1 C ARG 28  ? NH2 ? B ARG 22  NH2 
47  1 Y 1 C ARG 44  ? NH1 ? B ARG 38  NH1 
48  1 Y 1 C ARG 44  ? NH2 ? B ARG 38  NH2 
49  1 Y 1 C ARG 46  ? NH1 ? B ARG 40  NH1 
50  1 Y 1 C ARG 46  ? NH2 ? B ARG 40  NH2 
51  1 Y 1 C ARG 49  ? NH1 ? B ARG 43  NH1 
52  1 Y 1 C ARG 49  ? NH2 ? B ARG 43  NH2 
53  1 Y 1 C TYR 58  ? OH  ? B TYR 52  OH  
54  1 Y 1 C ARG 62  ? NH1 ? B ARG 56  NH1 
55  1 Y 1 C ARG 62  ? NH2 ? B ARG 56  NH2 
56  1 Y 1 C TYR 92  ? OH  ? B TYR 86  OH  
57  1 Y 1 H ARG 370 ? NH1 ? C ARG 61  NH1 
58  1 Y 1 H ARG 370 ? NH2 ? C ARG 61  NH2 
59  1 Y 1 H ARG 384 ? NH1 ? C ARG 75  NH1 
60  1 Y 1 H ARG 384 ? NH2 ? C ARG 75  NH2 
61  1 Y 1 H ARG 397 ? NH1 ? C ARG 88  NH1 
62  1 Y 1 H ARG 397 ? NH2 ? C ARG 88  NH2 
63  1 Y 1 H ARG 416 ? NH1 ? C ARG 107 NH1 
64  1 Y 1 H ARG 416 ? NH2 ? C ARG 107 NH2 
65  1 Y 1 H TYR 417 ? OH  ? C TYR 108 OH  
66  1 Y 1 H TYR 420 ? OH  ? C TYR 111 OH  
67  1 Y 1 H ARG 421 ? NH1 ? C ARG 112 NH1 
68  1 Y 1 H ARG 421 ? NH2 ? C ARG 112 NH2 
69  1 Y 1 H ARG 464 ? NH1 ? C ARG 155 NH1 
70  1 Y 1 H ARG 464 ? NH2 ? C ARG 155 NH2 
71  1 Y 1 H TYR 475 ? OH  ? C TYR 166 OH  
72  1 Y 1 H ARG 494 ? NH1 ? C ARG 185 NH1 
73  1 Y 1 H ARG 494 ? NH2 ? C ARG 185 NH2 
74  1 Y 1 H TYR 496 ? OH  ? C TYR 187 OH  
75  1 Y 1 H TYR 520 ? OH  ? C TYR 211 OH  
76  1 Y 1 H ARG 540 ? NH1 ? C ARG 231 NH1 
77  1 Y 1 H ARG 540 ? NH2 ? C ARG 231 NH2 
78  1 Y 1 H ARG 548 ? NH1 ? C ARG 239 NH1 
79  1 Y 1 H ARG 548 ? NH2 ? C ARG 239 NH2 
80  1 Y 1 H ARG 564 ? NH1 ? C ARG 255 NH1 
81  1 Y 1 H ARG 564 ? NH2 ? C ARG 255 NH2 
82  1 Y 1 H TRP 577 ? CH2 ? C TRP 268 CH2 
83  1 Y 1 H ARG 582 ? NH1 ? C ARG 273 NH1 
84  1 Y 1 H ARG 582 ? NH2 ? C ARG 273 NH2 
85  1 Y 1 H TYR 598 ? OH  ? C TYR 289 OH  
86  1 Y 1 H TYR 607 ? OH  ? C TYR 298 OH  
87  1 Y 1 H ARG 614 ? NH1 ? C ARG 305 NH1 
88  1 Y 1 H ARG 614 ? NH2 ? C ARG 305 NH2 
89  1 Y 1 H TYR 615 ? OH  ? C TYR 306 OH  
90  1 Y 1 H TRP 626 ? CH2 ? C TRP 317 CH2 
91  1 Y 1 H ARG 646 ? NH1 ? C ARG 337 NH1 
92  1 Y 1 H ARG 646 ? NH2 ? C ARG 337 NH2 
93  1 Y 1 H TYR 647 ? OH  ? C TYR 338 OH  
94  1 Y 1 H ARG 652 ? NH1 ? C ARG 343 NH1 
95  1 Y 1 H ARG 652 ? NH2 ? C ARG 343 NH2 
96  1 Y 1 H TYR 668 ? OH  ? C TYR 359 OH  
97  1 Y 1 H ARG 682 ? NH1 ? C ARG 373 NH1 
98  1 Y 1 H ARG 682 ? NH2 ? C ARG 373 NH2 
99  1 Y 1 I ARG 28  ? NH1 ? D ARG 22  NH1 
100 1 Y 1 I ARG 28  ? NH2 ? D ARG 22  NH2 
101 1 Y 1 I ARG 44  ? NH1 ? D ARG 38  NH1 
102 1 Y 1 I ARG 44  ? NH2 ? D ARG 38  NH2 
103 1 Y 1 I ARG 46  ? NH1 ? D ARG 40  NH1 
104 1 Y 1 I ARG 46  ? NH2 ? D ARG 40  NH2 
105 1 Y 1 I ARG 49  ? NH1 ? D ARG 43  NH1 
106 1 Y 1 I ARG 49  ? NH2 ? D ARG 43  NH2 
107 1 Y 1 I TYR 58  ? OH  ? D TYR 52  OH  
108 1 Y 1 I ARG 62  ? NH1 ? D ARG 56  NH1 
109 1 Y 1 I ARG 62  ? NH2 ? D ARG 56  NH2 
110 1 Y 1 I TYR 92  ? OH  ? D TYR 86  OH  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UBV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UBV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UBV 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8UBV 
_struct.title                        'Cryo-EM structure of dimeric FBXL17-BACH1BTB E3 ubiquitin ligase complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UBV 
_struct_keywords.text            'FBXL17, BACH1, F-box protein, Cullin, E3 ligase, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP FXL17_HUMAN Q9UF56 ? 1 
;CHREPPPETPDINQLPPSILLKIFSNLSLDERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQNII
EINISDCRSMSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDI
HFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRH
ITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKE
ITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAASS
;
310 
2 UNP BACH1_HUMAN O14867 ? 2 
;SVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKF
;
7   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UBV B 1 ? 392 ? Q9UF56 310 ? 701 ? 310 701 
2 2 8UBV C 1 ? 122 ? O14867 7   ? 128 ? 7   128 
3 1 8UBV H 1 ? 392 ? Q9UF56 310 ? 701 ? 310 701 
4 2 8UBV I 1 ? 122 ? O14867 7   ? 128 ? 7   128 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 68  ? ALA A 73  ? LEU B 377 ALA B 382 1 ? 6  
HELX_P HELX_P2  AA2 SER A 91  ? PHE A 100 ? SER B 400 PHE B 409 1 ? 10 
HELX_P HELX_P3  AA3 SER A 117 ? HIS A 127 ? SER B 426 HIS B 436 1 ? 11 
HELX_P HELX_P4  AA4 ASP A 144 ? CYS A 154 ? ASP B 453 CYS B 463 1 ? 11 
HELX_P HELX_P5  AA5 ASP A 170 ? GLY A 179 ? ASP B 479 GLY B 488 1 ? 10 
HELX_P HELX_P6  AA6 ASP A 196 ? ALA A 201 ? ASP B 505 ALA B 510 1 ? 6  
HELX_P HELX_P7  AA7 THR A 220 ? ILE A 225 ? THR B 529 ILE B 534 1 ? 6  
HELX_P HELX_P8  AA8 HIS A 226 ? LYS A 229 ? HIS B 535 LYS B 538 5 ? 4  
HELX_P HELX_P9  AA9 ASP A 245 ? CYS A 256 ? ASP B 554 CYS B 565 1 ? 12 
HELX_P HELX_P10 AB1 ASN A 271 ? ALA A 279 ? ASN B 580 ALA B 588 1 ? 9  
HELX_P HELX_P11 AB2 TYR A 298 ? SER A 307 ? TYR B 607 SER B 616 1 ? 10 
HELX_P HELX_P12 AB3 THR A 322 ? SER A 333 ? THR B 631 SER B 642 1 ? 12 
HELX_P HELX_P13 AB4 VAL A 350 ? TYR A 359 ? VAL B 659 TYR B 668 1 ? 10 
HELX_P HELX_P14 AB5 CYS A 371 ? ARG A 377 ? CYS B 680 ARG B 686 1 ? 7  
HELX_P HELX_P15 AB6 THR B 12  ? LYS B 23  ? THR C 18  LYS C 29  1 ? 12 
HELX_P HELX_P16 AB7 ARG B 43  ? SER B 50  ? ARG C 49  SER C 56  1 ? 8  
HELX_P HELX_P17 AB8 SER B 50  ? VAL B 58  ? SER C 56  VAL C 64  1 ? 9  
HELX_P HELX_P18 AB9 THR B 74  ? ALA B 88  ? THR C 80  ALA C 94  1 ? 15 
HELX_P HELX_P19 AC1 VAL B 97  ? CYS B 101 ? VAL C 103 CYS C 107 5 ? 5  
HELX_P HELX_P20 AC2 LEU C 68  ? ALA C 73  ? LEU H 377 ALA H 382 1 ? 6  
HELX_P HELX_P21 AC3 SER C 91  ? PHE C 100 ? SER H 400 PHE H 409 1 ? 10 
HELX_P HELX_P22 AC4 ASP C 118 ? HIS C 127 ? ASP H 427 HIS H 436 1 ? 10 
HELX_P HELX_P23 AC5 THR C 143 ? CYS C 154 ? THR H 452 CYS H 463 1 ? 12 
HELX_P HELX_P24 AC6 ASP C 170 ? GLY C 179 ? ASP H 479 GLY H 488 1 ? 10 
HELX_P HELX_P25 AC7 THR C 195 ? VAL C 199 ? THR H 504 VAL H 508 5 ? 5  
HELX_P HELX_P26 AC8 THR C 220 ? LEU C 227 ? THR H 529 LEU H 536 1 ? 8  
HELX_P HELX_P27 AC9 ASP C 245 ? CYS C 256 ? ASP H 554 CYS H 565 1 ? 12 
HELX_P HELX_P28 AD1 ASN C 271 ? GLY C 282 ? ASN H 580 GLY H 591 1 ? 12 
HELX_P HELX_P29 AD2 TYR C 298 ? SER C 307 ? TYR H 607 SER H 616 1 ? 10 
HELX_P HELX_P30 AD3 THR C 322 ? SER C 333 ? THR H 631 SER H 642 1 ? 12 
HELX_P HELX_P31 AD4 VAL C 350 ? TYR C 359 ? VAL H 659 TYR H 668 1 ? 10 
HELX_P HELX_P32 AD5 SER D 11  ? LYS D 23  ? SER I 17  LYS I 29  1 ? 13 
HELX_P HELX_P33 AD6 ARG D 43  ? SER D 50  ? ARG I 49  SER I 56  1 ? 8  
HELX_P HELX_P34 AD7 SER D 50  ? GLY D 59  ? SER I 56  GLY I 65  1 ? 10 
HELX_P HELX_P35 AD8 THR D 74  ? ALA D 88  ? THR I 80  ALA I 94  1 ? 15 
HELX_P HELX_P36 AD9 VAL D 97  ? CYS D 101 ? VAL I 103 CYS I 107 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 87  SG ? ? ? 1_555 A CYS 113 SG ? ? B CYS 396 B CYS 422 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ? ? B CYS 101 SG ? ? ? 1_555 D CYS 103 SG ? ? C CYS 107 I CYS 109 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf3 disulf ? ? B CYS 103 SG ? ? ? 1_555 D CYS 101 SG ? ? C CYS 109 I CYS 107 1_555 ? ? ? ? ? ? ? 2.045 ? ? 
disulf4 disulf ? ? C CYS 87  SG ? ? ? 1_555 C CYS 113 SG ? ? H CYS 396 H CYS 422 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 87  ? CYS A 113 ? CYS B 396 ? 1_555 CYS B 422 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 101 ? CYS D 103 ? CYS C 107 ? 1_555 CYS I 109 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 103 ? CYS D 101 ? CYS C 109 ? 1_555 CYS I 107 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS C 87  ? CYS C 113 ? CYS H 396 ? 1_555 CYS H 422 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          VAL 
_struct_mon_prot_cis.label_seq_id           109 
_struct_mon_prot_cis.label_asym_id          D 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           VAL 
_struct_mon_prot_cis.auth_seq_id            115 
_struct_mon_prot_cis.auth_asym_id           I 
_struct_mon_prot_cis.pdbx_label_comp_id_2   HIS 
_struct_mon_prot_cis.pdbx_label_seq_id_2    110 
_struct_mon_prot_cis.pdbx_label_asym_id_2   D 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    HIS 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     116 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    I 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -7.42 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 6 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA5 1 2 ? parallel      
AA5 2 3 ? parallel      
AA5 3 4 ? parallel      
AA5 4 5 ? parallel      
AA5 5 6 ? parallel      
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 261 ? LEU A 262 ? SER B 570 LEU B 571 
AA1 2 GLU A 287 ? LEU A 290 ? GLU B 596 LEU B 599 
AA1 3 THR A 312 ? VAL A 315 ? THR B 621 VAL B 624 
AA2 1 GLN B 37  ? ALA B 41  ? GLN C 43  ALA C 47  
AA2 2 VAL B 30  ? VAL B 34  ? VAL C 36  VAL C 40  
AA2 3 ILE B 67  ? THR B 68  ? ILE C 73  THR C 74  
AA3 1 LYS B 89  ? LEU B 90  ? LYS C 95  LEU C 96  
AA3 2 LEU D 92  ? SER D 93  ? LEU I 98  SER I 99  
AA4 1 VAL C 134 ? HIS C 135 ? VAL H 443 HIS H 444 
AA4 2 ILE C 160 ? HIS C 161 ? ILE H 469 HIS H 470 
AA5 1 ARG C 185 ? TYR C 187 ? ARG H 494 TYR H 496 
AA5 2 TYR C 211 ? GLY C 213 ? TYR H 520 GLY H 522 
AA5 3 SER C 235 ? ASP C 237 ? SER H 544 ASP H 546 
AA5 4 SER C 261 ? LEU C 262 ? SER H 570 LEU H 571 
AA5 5 GLU C 287 ? LEU C 290 ? GLU H 596 LEU H 599 
AA5 6 THR C 312 ? VAL C 315 ? THR H 621 VAL H 624 
AA6 1 GLN D 37  ? ALA D 41  ? GLN I 43  ALA I 47  
AA6 2 VAL D 30  ? VAL D 34  ? VAL I 36  VAL I 40  
AA6 3 LEU D 65  ? THR D 68  ? LEU I 71  THR I 74  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 262 ? N LEU B 571 O GLU A 287 ? O GLU B 596 
AA1 2 3 N LEU A 290 ? N LEU B 599 O ASP A 314 ? O ASP B 623 
AA2 1 2 O ALA B 41  ? O ALA C 47  N VAL B 30  ? N VAL C 36  
AA2 2 3 N PHE B 33  ? N PHE C 39  O ILE B 67  ? O ILE C 73  
AA3 1 2 N LEU B 90  ? N LEU C 96  O LEU D 92  ? O LEU I 98  
AA4 1 2 O VAL C 134 ? O VAL H 443 N HIS C 161 ? N HIS H 470 
AA5 1 2 N ILE C 186 ? N ILE H 495 O GLY C 213 ? O GLY H 522 
AA5 2 3 N VAL C 212 ? N VAL H 521 O SER C 235 ? O SER H 544 
AA5 3 4 N LEU C 236 ? N LEU H 545 O SER C 261 ? O SER H 570 
AA5 4 5 N LEU C 262 ? N LEU H 571 O GLU C 287 ? O GLU H 596 
AA5 5 6 N LEU C 288 ? N LEU H 597 O ASP C 314 ? O ASP H 623 
AA6 1 2 O PHE D 39  ? O PHE I 45  N ILE D 32  ? N ILE I 38  
AA6 2 3 N PHE D 33  ? N PHE I 39  O ILE D 67  ? O ILE I 73  
# 
_pdbx_entry_details.entry_id                   8UBV 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   H GLN 592 ? ? OG1 H THR 618 ? ? 1.96 
2 1 O   B ILE 619 ? ? OG  B SER 644 ? ? 2.08 
3 1 OD1 C ASN 25  ? ? NZ  C LYS 29  ? ? 2.09 
4 1 OG1 H THR 452 ? ? OE1 H GLU 454 ? ? 2.11 
5 1 O   H LYS 566 ? ? ND2 H ASN 593 ? ? 2.12 
6 1 O   C TYR 58  ? ? OG  C SER 61  ? ? 2.14 
7 1 O   B GLN 592 ? ? OG1 B THR 618 ? ? 2.17 
8 1 OD1 B ASP 401 ? ? OG1 B THR 428 ? ? 2.18 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA C CYS 109 ? ? CB C CYS 109 ? ? SG C CYS 109 ? ? 121.29 114.20 7.09  1.10 N 
2 1 C  C VAL 115 ? ? N  C HIS 116 ? ? CA C HIS 116 ? ? 142.10 121.70 20.40 2.50 Y 
3 1 CA H LEU 367 ? ? CB H LEU 367 ? ? CG H LEU 367 ? ? 129.77 115.30 14.47 2.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN B 371 ? ? 43.55   -135.01 
2  1 GLN B 372 ? ? -93.71  58.90   
3  1 LEU B 378 ? ? -55.30  -5.19   
4  1 ALA B 382 ? ? -100.84 59.81   
5  1 ASN B 387 ? ? -145.09 46.56   
6  1 ARG B 397 ? ? -142.38 14.57   
7  1 SER B 400 ? ? -123.80 -169.87 
8  1 CYS B 411 ? ? 51.58   70.04   
9  1 HIS B 444 ? ? -68.53  79.88   
10 1 THR B 452 ? ? -68.40  -177.36 
11 1 ARG B 464 ? ? -93.74  48.97   
12 1 ASP B 479 ? ? -130.24 -40.02  
13 1 LYS B 487 ? ? -68.64  -77.03  
14 1 GLU B 499 ? ? -68.75  69.27   
15 1 LEU B 502 ? ? 65.36   -4.63   
16 1 VAL B 508 ? ? -124.52 -53.16  
17 1 HIS B 514 ? ? -103.28 -62.83  
18 1 SER B 527 ? ? -98.78  41.06   
19 1 LYS B 538 ? ? -64.80  -70.72  
20 1 HIS B 549 ? ? 61.16   70.84   
21 1 GLU B 552 ? ? 52.13   72.14   
22 1 ASN B 572 ? ? -94.99  -63.92  
23 1 LEU B 573 ? ? 38.52   41.70   
24 1 SER B 601 ? ? 59.08   18.97   
25 1 PHE B 673 ? ? 65.33   153.48  
26 1 SER B 674 ? ? -143.98 26.22   
27 1 ASP B 679 ? ? -80.28  48.89   
28 1 CYS B 680 ? ? -131.58 -40.49  
29 1 LYS C 29  ? ? -85.77  43.77   
30 1 ASP C 35  ? ? -92.48  -64.35  
31 1 CYS C 107 ? ? -95.87  57.39   
32 1 LYS C 108 ? ? -143.71 -11.88  
33 1 GLU C 111 ? ? 66.89   -8.84   
34 1 PHE C 112 ? ? 38.67   46.81   
35 1 SER C 114 ? ? 72.66   -85.42  
36 1 HIS C 116 ? ? -144.24 38.13   
37 1 GLN H 371 ? ? 42.53   -136.02 
38 1 ARG H 397 ? ? -141.61 14.47   
39 1 SER H 400 ? ? -128.62 -164.23 
40 1 HIS H 444 ? ? -67.48  82.71   
41 1 ARG H 464 ? ? -96.05  55.20   
42 1 PHE H 471 ? ? -116.66 50.44   
43 1 TYR H 475 ? ? -85.87  47.72   
44 1 LYS H 476 ? ? -145.01 18.79   
45 1 GLN H 498 ? ? -145.17 -156.19 
46 1 GLU H 499 ? ? -67.08  63.65   
47 1 VAL H 508 ? ? -129.07 -57.56  
48 1 GLN H 519 ? ? -130.68 -45.76  
49 1 PHE H 523 ? ? -144.67 44.17   
50 1 SER H 527 ? ? -100.61 43.49   
51 1 HIS H 549 ? ? 62.76   61.15   
52 1 GLU H 552 ? ? 57.22   71.39   
53 1 LEU H 568 ? ? -166.19 115.13  
54 1 LEU H 648 ? ? -92.72  48.15   
55 1 PHE H 673 ? ? 61.67   173.44  
56 1 LYS H 681 ? ? -98.09  -61.62  
57 1 LYS I 29  ? ? -83.16  48.11   
58 1 GLU I 41  ? ? 43.52   27.93   
59 1 ALA I 47  ? ? -161.23 -164.53 
60 1 ASP I 68  ? ? -68.18  -178.24 
61 1 CYS I 107 ? ? -68.17  77.46   
62 1 CYS I 109 ? ? 58.13   1.86    
63 1 GLU I 111 ? ? 65.83   -73.45  
64 1 PHE I 112 ? ? 46.47   -123.63 
65 1 LEU I 113 ? ? 67.75   -9.65   
66 1 VAL I 115 ? ? -122.91 -56.09  
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 ILE B 485 ? ? ALA B 486 ? ? 145.21 
2 1 VAL C 115 ? ? HIS C 116 ? ? -31.39 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8UBV 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'RIGID BODY FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  6WCQ 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                6WCQ 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    8UBV 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'BACK PROJECTION' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  4.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               71155 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'The structure of dimeric BFXL17-BACH1BTB' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8UBV 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             5000 
_em_imaging.nominal_defocus_max             25000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        ? 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8UBV 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8UBV 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B CYS 310 ? A CYS 1   
2   1 Y 1 B HIS 311 ? A HIS 2   
3   1 Y 1 B ARG 312 ? A ARG 3   
4   1 Y 1 B GLU 313 ? A GLU 4   
5   1 Y 1 B PRO 314 ? A PRO 5   
6   1 Y 1 B PRO 315 ? A PRO 6   
7   1 Y 1 B PRO 316 ? A PRO 7   
8   1 Y 1 B GLU 317 ? A GLU 8   
9   1 Y 1 B THR 318 ? A THR 9   
10  1 Y 1 B PRO 319 ? A PRO 10  
11  1 Y 1 B ASP 320 ? A ASP 11  
12  1 Y 1 B ILE 321 ? A ILE 12  
13  1 Y 1 B ASN 322 ? A ASN 13  
14  1 Y 1 B GLN 323 ? A GLN 14  
15  1 Y 1 B LEU 324 ? A LEU 15  
16  1 Y 1 B PRO 325 ? A PRO 16  
17  1 Y 1 B PRO 326 ? A PRO 17  
18  1 Y 1 B SER 327 ? A SER 18  
19  1 Y 1 B ILE 328 ? A ILE 19  
20  1 Y 1 B LEU 329 ? A LEU 20  
21  1 Y 1 B LEU 330 ? A LEU 21  
22  1 Y 1 B LYS 331 ? A LYS 22  
23  1 Y 1 B ILE 332 ? A ILE 23  
24  1 Y 1 B PHE 333 ? A PHE 24  
25  1 Y 1 B SER 334 ? A SER 25  
26  1 Y 1 B ASN 335 ? A ASN 26  
27  1 Y 1 B LEU 336 ? A LEU 27  
28  1 Y 1 B SER 337 ? A SER 28  
29  1 Y 1 B LEU 338 ? A LEU 29  
30  1 Y 1 B ASP 339 ? A ASP 30  
31  1 Y 1 B GLU 340 ? A GLU 31  
32  1 Y 1 B ARG 341 ? A ARG 32  
33  1 Y 1 B CYS 342 ? A CYS 33  
34  1 Y 1 B LEU 343 ? A LEU 34  
35  1 Y 1 B SER 344 ? A SER 35  
36  1 Y 1 B ALA 345 ? A ALA 36  
37  1 Y 1 B SER 346 ? A SER 37  
38  1 Y 1 B LEU 347 ? A LEU 38  
39  1 Y 1 B VAL 348 ? A VAL 39  
40  1 Y 1 B CYS 349 ? A CYS 40  
41  1 Y 1 B LYS 350 ? A LYS 41  
42  1 Y 1 B TYR 351 ? A TYR 42  
43  1 Y 1 B TRP 352 ? A TRP 43  
44  1 Y 1 B ARG 353 ? A ARG 44  
45  1 Y 1 B ASP 354 ? A ASP 45  
46  1 Y 1 B LEU 355 ? A LEU 46  
47  1 Y 1 B CYS 356 ? A CYS 47  
48  1 Y 1 B LEU 357 ? A LEU 48  
49  1 Y 1 B ASP 358 ? A ASP 49  
50  1 Y 1 B PHE 359 ? A PHE 50  
51  1 Y 1 B GLN 360 ? A GLN 51  
52  1 Y 1 B PHE 361 ? A PHE 52  
53  1 Y 1 B TRP 362 ? A TRP 53  
54  1 Y 1 B ALA 687 ? A ALA 378 
55  1 Y 1 B TYR 688 ? A TYR 379 
56  1 Y 1 B GLN 689 ? A GLN 380 
57  1 Y 1 B MET 690 ? A MET 381 
58  1 Y 1 B GLY 691 ? A GLY 382 
59  1 Y 1 B TRP 692 ? A TRP 383 
60  1 Y 1 B THR 693 ? A THR 384 
61  1 Y 1 B PRO 694 ? A PRO 385 
62  1 Y 1 B ASN 695 ? A ASN 386 
63  1 Y 1 B MET 696 ? A MET 387 
64  1 Y 1 B SER 697 ? A SER 388 
65  1 Y 1 B ALA 698 ? A ALA 389 
66  1 Y 1 B ALA 699 ? A ALA 390 
67  1 Y 1 B SER 700 ? A SER 391 
68  1 Y 1 B SER 701 ? A SER 392 
69  1 Y 1 C SER 7   ? B SER 1   
70  1 Y 1 C VAL 8   ? B VAL 2   
71  1 Y 1 C PHE 9   ? B PHE 3   
72  1 Y 1 C ALA 10  ? B ALA 4   
73  1 Y 1 C TYR 11  ? B TYR 5   
74  1 Y 1 C GLU 12  ? B GLU 6   
75  1 Y 1 C SER 13  ? B SER 7   
76  1 Y 1 C SER 14  ? B SER 8   
77  1 Y 1 C VAL 15  ? B VAL 9   
78  1 Y 1 C HIS 16  ? B HIS 10  
79  1 Y 1 C GLU 119 ? B GLU 113 
80  1 Y 1 C GLU 120 ? B GLU 114 
81  1 Y 1 C SER 121 ? B SER 115 
82  1 Y 1 C CYS 122 ? B CYS 116 
83  1 Y 1 C PHE 123 ? B PHE 117 
84  1 Y 1 C GLN 124 ? B GLN 118 
85  1 Y 1 C PHE 125 ? B PHE 119 
86  1 Y 1 C LEU 126 ? B LEU 120 
87  1 Y 1 C LYS 127 ? B LYS 121 
88  1 Y 1 C PHE 128 ? B PHE 122 
89  1 Y 1 H CYS 310 ? C CYS 1   
90  1 Y 1 H HIS 311 ? C HIS 2   
91  1 Y 1 H ARG 312 ? C ARG 3   
92  1 Y 1 H GLU 313 ? C GLU 4   
93  1 Y 1 H PRO 314 ? C PRO 5   
94  1 Y 1 H PRO 315 ? C PRO 6   
95  1 Y 1 H PRO 316 ? C PRO 7   
96  1 Y 1 H GLU 317 ? C GLU 8   
97  1 Y 1 H THR 318 ? C THR 9   
98  1 Y 1 H PRO 319 ? C PRO 10  
99  1 Y 1 H ASP 320 ? C ASP 11  
100 1 Y 1 H ILE 321 ? C ILE 12  
101 1 Y 1 H ASN 322 ? C ASN 13  
102 1 Y 1 H GLN 323 ? C GLN 14  
103 1 Y 1 H LEU 324 ? C LEU 15  
104 1 Y 1 H PRO 325 ? C PRO 16  
105 1 Y 1 H PRO 326 ? C PRO 17  
106 1 Y 1 H SER 327 ? C SER 18  
107 1 Y 1 H ILE 328 ? C ILE 19  
108 1 Y 1 H LEU 329 ? C LEU 20  
109 1 Y 1 H LEU 330 ? C LEU 21  
110 1 Y 1 H LYS 331 ? C LYS 22  
111 1 Y 1 H ILE 332 ? C ILE 23  
112 1 Y 1 H PHE 333 ? C PHE 24  
113 1 Y 1 H SER 334 ? C SER 25  
114 1 Y 1 H ASN 335 ? C ASN 26  
115 1 Y 1 H LEU 336 ? C LEU 27  
116 1 Y 1 H SER 337 ? C SER 28  
117 1 Y 1 H LEU 338 ? C LEU 29  
118 1 Y 1 H ASP 339 ? C ASP 30  
119 1 Y 1 H GLU 340 ? C GLU 31  
120 1 Y 1 H ARG 341 ? C ARG 32  
121 1 Y 1 H CYS 342 ? C CYS 33  
122 1 Y 1 H LEU 343 ? C LEU 34  
123 1 Y 1 H SER 344 ? C SER 35  
124 1 Y 1 H ALA 345 ? C ALA 36  
125 1 Y 1 H SER 346 ? C SER 37  
126 1 Y 1 H LEU 347 ? C LEU 38  
127 1 Y 1 H VAL 348 ? C VAL 39  
128 1 Y 1 H CYS 349 ? C CYS 40  
129 1 Y 1 H LYS 350 ? C LYS 41  
130 1 Y 1 H TYR 351 ? C TYR 42  
131 1 Y 1 H TRP 352 ? C TRP 43  
132 1 Y 1 H ARG 353 ? C ARG 44  
133 1 Y 1 H ASP 354 ? C ASP 45  
134 1 Y 1 H LEU 355 ? C LEU 46  
135 1 Y 1 H CYS 356 ? C CYS 47  
136 1 Y 1 H LEU 357 ? C LEU 48  
137 1 Y 1 H ASP 358 ? C ASP 49  
138 1 Y 1 H PHE 359 ? C PHE 50  
139 1 Y 1 H GLN 360 ? C GLN 51  
140 1 Y 1 H PHE 361 ? C PHE 52  
141 1 Y 1 H TRP 362 ? C TRP 53  
142 1 Y 1 H ARG 686 ? C ARG 377 
143 1 Y 1 H ALA 687 ? C ALA 378 
144 1 Y 1 H TYR 688 ? C TYR 379 
145 1 Y 1 H GLN 689 ? C GLN 380 
146 1 Y 1 H MET 690 ? C MET 381 
147 1 Y 1 H GLY 691 ? C GLY 382 
148 1 Y 1 H TRP 692 ? C TRP 383 
149 1 Y 1 H THR 693 ? C THR 384 
150 1 Y 1 H PRO 694 ? C PRO 385 
151 1 Y 1 H ASN 695 ? C ASN 386 
152 1 Y 1 H MET 696 ? C MET 387 
153 1 Y 1 H SER 697 ? C SER 388 
154 1 Y 1 H ALA 698 ? C ALA 389 
155 1 Y 1 H ALA 699 ? C ALA 390 
156 1 Y 1 H SER 700 ? C SER 391 
157 1 Y 1 H SER 701 ? C SER 392 
158 1 Y 1 I SER 7   ? D SER 1   
159 1 Y 1 I VAL 8   ? D VAL 2   
160 1 Y 1 I PHE 9   ? D PHE 3   
161 1 Y 1 I ALA 10  ? D ALA 4   
162 1 Y 1 I TYR 11  ? D TYR 5   
163 1 Y 1 I GLU 12  ? D GLU 6   
164 1 Y 1 I SER 13  ? D SER 7   
165 1 Y 1 I SER 14  ? D SER 8   
166 1 Y 1 I VAL 15  ? D VAL 9   
167 1 Y 1 I GLU 119 ? D GLU 113 
168 1 Y 1 I GLU 120 ? D GLU 114 
169 1 Y 1 I SER 121 ? D SER 115 
170 1 Y 1 I CYS 122 ? D CYS 116 
171 1 Y 1 I PHE 123 ? D PHE 117 
172 1 Y 1 I GLN 124 ? D GLN 118 
173 1 Y 1 I PHE 125 ? D PHE 119 
174 1 Y 1 I LEU 126 ? D LEU 120 
175 1 Y 1 I LYS 127 ? D LYS 121 
176 1 Y 1 I PHE 128 ? D PHE 122 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-09-25 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8UBV 
_em_admin.last_update        2025-01-08 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'Cryo-EM structure of dimeric FBXL17-BACH1BTB E3 ubiquitin ligase complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7111 
_em_entity_assembly_recombinant.organism             'Trichoplusia ni' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?              ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 SerialEM       ? 
MASKING                         ? 3  ? ? ? ?              ? 
'CTF CORRECTION'                ? 4  1 ? ? ?              ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?              ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?              ? 
'MODEL FITTING'                 ? 7  ? 1 ? 'UCSF Chimera' ? 
'MODEL FITTING'                 ? 8  ? 1 ? PHENIX         ? 
OTHER                           ? 9  ? ? ? ?              ? 
'MODEL REFINEMENT'              ? 10 ? 1 ? ?              ? 
'INITIAL EULER ASSIGNMENT'      ? 11 1 ? ? cryoSPARC      ? 
'FINAL EULER ASSIGNMENT'        ? 12 1 ? ? cryoSPARC      ? 
CLASSIFICATION                  ? 13 1 ? ? cryoSPARC      ? 
RECONSTRUCTION                  ? 14 1 ? ? cryoSPARC      ? 
'VOLUME SELECTION'              ? 15 1 1 1 ?              ? 
'SERIES ALIGNMENT'              ? 16 1 1 1 ?              ? 
'MOLECULAR REPLACEMENT'         ? 17 1 1 1 ?              ? 
'LATTICE DISTORTION CORRECTION' ? 18 1 1 1 ?              ? 
'SYMMETRY DETERMINATION'        ? 19 1 1 1 ?              ? 
'CRYSTALLOGRAPHY MERGING'       ? 20 1 1 1 ?              ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Howard Hughes Medical Institute (HHMI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6WCQ 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8UBV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . LYS A 1 54  ? 158.016 128.484 162.413 1.00 406.33 ? 363 LYS B N   1 
ATOM 2    C CA  . LYS A 1 54  ? 159.181 127.978 163.129 1.00 406.33 ? 363 LYS B CA  1 
ATOM 3    C C   . LYS A 1 54  ? 160.142 129.112 163.468 1.00 406.33 ? 363 LYS B C   1 
ATOM 4    O O   . LYS A 1 54  ? 160.704 129.153 164.561 1.00 406.33 ? 363 LYS B O   1 
ATOM 5    C CB  . LYS A 1 54  ? 159.889 126.894 162.304 1.00 406.33 ? 363 LYS B CB  1 
ATOM 6    C CG  . LYS A 1 54  ? 160.458 127.364 160.968 1.00 406.33 ? 363 LYS B CG  1 
ATOM 7    C CD  . LYS A 1 54  ? 160.627 126.211 159.995 1.00 406.33 ? 363 LYS B CD  1 
ATOM 8    C CE  . LYS A 1 54  ? 161.867 125.400 160.313 1.00 406.33 ? 363 LYS B CE  1 
ATOM 9    N NZ  . LYS A 1 54  ? 161.750 124.008 159.804 1.00 406.33 ? 363 LYS B NZ  1 
ATOM 10   N N   . GLN A 1 55  ? 160.321 130.035 162.526 1.00 402.63 ? 364 GLN B N   1 
ATOM 11   C CA  . GLN A 1 55  ? 161.213 131.177 162.708 1.00 402.63 ? 364 GLN B CA  1 
ATOM 12   C C   . GLN A 1 55  ? 160.564 132.364 162.015 1.00 402.63 ? 364 GLN B C   1 
ATOM 13   O O   . GLN A 1 55  ? 160.746 132.541 160.806 1.00 402.63 ? 364 GLN B O   1 
ATOM 14   C CB  . GLN A 1 55  ? 162.600 130.901 162.124 1.00 402.63 ? 364 GLN B CB  1 
ATOM 15   C CG  . GLN A 1 55  ? 163.348 129.707 162.711 1.00 402.63 ? 364 GLN B CG  1 
ATOM 16   C CD  . GLN A 1 55  ? 163.788 129.920 164.147 1.00 402.63 ? 364 GLN B CD  1 
ATOM 17   O OE1 . GLN A 1 55  ? 164.731 130.663 164.415 1.00 402.63 ? 364 GLN B OE1 1 
ATOM 18   N NE2 . GLN A 1 55  ? 163.111 129.258 165.077 1.00 402.63 ? 364 GLN B NE2 1 
ATOM 19   N N   . LEU A 1 56  ? 159.820 133.180 162.763 1.00 399.06 ? 365 LEU B N   1 
ATOM 20   C CA  . LEU A 1 56  ? 159.149 134.310 162.129 1.00 399.06 ? 365 LEU B CA  1 
ATOM 21   C C   . LEU A 1 56  ? 160.157 135.371 161.703 1.00 399.06 ? 365 LEU B C   1 
ATOM 22   O O   . LEU A 1 56  ? 160.306 135.653 160.510 1.00 399.06 ? 365 LEU B O   1 
ATOM 23   C CB  . LEU A 1 56  ? 158.094 134.910 163.064 1.00 399.06 ? 365 LEU B CB  1 
ATOM 24   C CG  . LEU A 1 56  ? 156.768 134.156 163.188 1.00 399.06 ? 365 LEU B CG  1 
ATOM 25   C CD1 . LEU A 1 56  ? 155.684 135.061 163.750 1.00 399.06 ? 365 LEU B CD1 1 
ATOM 26   C CD2 . LEU A 1 56  ? 156.348 133.584 161.851 1.00 399.06 ? 365 LEU B CD2 1 
ATOM 27   N N   . ASP A 1 57  ? 160.874 135.945 162.667 1.00 390.40 ? 366 ASP B N   1 
ATOM 28   C CA  . ASP A 1 57  ? 161.895 136.957 162.408 1.00 390.40 ? 366 ASP B CA  1 
ATOM 29   C C   . ASP A 1 57  ? 161.350 138.053 161.493 1.00 390.40 ? 366 ASP B C   1 
ATOM 30   O O   . ASP A 1 57  ? 161.984 138.474 160.524 1.00 390.40 ? 366 ASP B O   1 
ATOM 31   C CB  . ASP A 1 57  ? 163.155 136.318 161.819 1.00 390.40 ? 366 ASP B CB  1 
ATOM 32   C CG  . ASP A 1 57  ? 164.398 137.162 162.036 1.00 390.40 ? 366 ASP B CG  1 
ATOM 33   O OD1 . ASP A 1 57  ? 164.261 138.352 162.392 1.00 390.40 ? 366 ASP B OD1 1 
ATOM 34   O OD2 . ASP A 1 57  ? 165.514 136.632 161.850 1.00 390.40 ? 366 ASP B OD2 1 
ATOM 35   N N   . LEU A 1 58  ? 160.147 138.520 161.831 1.00 382.30 ? 367 LEU B N   1 
ATOM 36   C CA  . LEU A 1 58  ? 159.417 139.491 161.025 1.00 382.30 ? 367 LEU B CA  1 
ATOM 37   C C   . LEU A 1 58  ? 159.846 140.922 161.346 1.00 382.30 ? 367 LEU B C   1 
ATOM 38   O O   . LEU A 1 58  ? 159.095 141.880 161.127 1.00 382.30 ? 367 LEU B O   1 
ATOM 39   C CB  . LEU A 1 58  ? 157.912 139.263 161.222 1.00 382.30 ? 367 LEU B CB  1 
ATOM 40   C CG  . LEU A 1 58  ? 156.740 139.895 160.457 1.00 382.30 ? 367 LEU B CG  1 
ATOM 41   C CD1 . LEU A 1 58  ? 155.593 138.902 160.461 1.00 382.30 ? 367 LEU B CD1 1 
ATOM 42   C CD2 . LEU A 1 58  ? 156.246 141.184 161.072 1.00 382.30 ? 367 LEU B CD2 1 
ATOM 43   N N   . SER A 1 59  ? 161.073 141.080 161.835 1.00 403.11 ? 368 SER B N   1 
ATOM 44   C CA  . SER A 1 59  ? 161.576 142.370 162.283 1.00 403.11 ? 368 SER B CA  1 
ATOM 45   C C   . SER A 1 59  ? 161.674 143.364 161.133 1.00 403.11 ? 368 SER B C   1 
ATOM 46   O O   . SER A 1 59  ? 162.009 143.002 160.002 1.00 403.11 ? 368 SER B O   1 
ATOM 47   C CB  . SER A 1 59  ? 162.950 142.192 162.927 1.00 403.11 ? 368 SER B CB  1 
ATOM 48   O OG  . SER A 1 59  ? 163.865 141.604 162.017 1.00 403.11 ? 368 SER B OG  1 
ATOM 49   N N   . SER A 1 60  ? 161.385 144.630 161.440 1.00 391.00 ? 369 SER B N   1 
ATOM 50   C CA  . SER A 1 60  ? 161.532 145.735 160.495 1.00 391.00 ? 369 SER B CA  1 
ATOM 51   C C   . SER A 1 60  ? 160.701 145.500 159.232 1.00 391.00 ? 369 SER B C   1 
ATOM 52   O O   . SER A 1 60  ? 161.129 145.787 158.112 1.00 391.00 ? 369 SER B O   1 
ATOM 53   C CB  . SER A 1 60  ? 163.009 145.964 160.155 1.00 391.00 ? 369 SER B CB  1 
ATOM 54   O OG  . SER A 1 60  ? 163.183 147.091 159.317 1.00 391.00 ? 369 SER B OG  1 
ATOM 55   N N   . ARG A 1 61  ? 159.490 144.978 159.425 1.00 399.17 ? 370 ARG B N   1 
ATOM 56   C CA  . ARG A 1 61  ? 158.541 144.777 158.337 1.00 399.17 ? 370 ARG B CA  1 
ATOM 57   C C   . ARG A 1 61  ? 157.780 146.039 157.969 1.00 399.17 ? 370 ARG B C   1 
ATOM 58   O O   . ARG A 1 61  ? 157.046 146.025 156.977 1.00 399.17 ? 370 ARG B O   1 
ATOM 59   C CB  . ARG A 1 61  ? 157.536 143.672 158.688 1.00 399.17 ? 370 ARG B CB  1 
ATOM 60   C CG  . ARG A 1 61  ? 157.312 142.640 157.589 1.00 399.17 ? 370 ARG B CG  1 
ATOM 61   C CD  . ARG A 1 61  ? 158.372 141.559 157.552 1.00 399.17 ? 370 ARG B CD  1 
ATOM 62   N NE  . ARG A 1 61  ? 158.118 140.608 156.475 1.00 399.17 ? 370 ARG B NE  1 
ATOM 63   C CZ  . ARG A 1 61  ? 159.002 139.727 156.027 1.00 399.17 ? 370 ARG B CZ  1 
ATOM 64   N N   . GLN A 1 62  ? 157.954 147.126 158.723 1.00 403.04 ? 371 GLN B N   1 
ATOM 65   C CA  . GLN A 1 62  ? 157.209 148.362 158.508 1.00 403.04 ? 371 GLN B CA  1 
ATOM 66   C C   . GLN A 1 62  ? 155.730 148.089 158.249 1.00 403.04 ? 371 GLN B C   1 
ATOM 67   O O   . GLN A 1 62  ? 155.122 147.264 158.937 1.00 403.04 ? 371 GLN B O   1 
ATOM 68   C CB  . GLN A 1 62  ? 157.823 149.153 157.351 1.00 403.04 ? 371 GLN B CB  1 
ATOM 69   C CG  . GLN A 1 62  ? 159.343 149.287 157.407 1.00 403.04 ? 371 GLN B CG  1 
ATOM 70   C CD  . GLN A 1 62  ? 159.821 150.074 158.618 1.00 403.04 ? 371 GLN B CD  1 
ATOM 71   O OE1 . GLN A 1 62  ? 159.088 150.893 159.172 1.00 403.04 ? 371 GLN B OE1 1 
ATOM 72   N NE2 . GLN A 1 62  ? 161.059 149.831 159.028 1.00 403.04 ? 371 GLN B NE2 1 
ATOM 73   N N   . GLN A 1 63  ? 155.152 148.750 157.249 1.00 407.88 ? 372 GLN B N   1 
ATOM 74   C CA  . GLN A 1 63  ? 153.718 148.646 156.968 1.00 407.88 ? 372 GLN B CA  1 
ATOM 75   C C   . GLN A 1 63  ? 153.412 147.574 155.924 1.00 407.88 ? 372 GLN B C   1 
ATOM 76   O O   . GLN A 1 63  ? 152.830 147.861 154.880 1.00 407.88 ? 372 GLN B O   1 
ATOM 77   C CB  . GLN A 1 63  ? 153.178 149.998 156.518 1.00 407.88 ? 372 GLN B CB  1 
ATOM 78   C CG  . GLN A 1 63  ? 153.051 151.039 157.613 1.00 407.88 ? 372 GLN B CG  1 
ATOM 79   C CD  . GLN A 1 63  ? 154.348 151.777 157.867 1.00 407.88 ? 372 GLN B CD  1 
ATOM 80   O OE1 . GLN A 1 63  ? 155.037 152.187 156.933 1.00 407.88 ? 372 GLN B OE1 1 
ATOM 81   N NE2 . GLN A 1 63  ? 154.679 151.968 159.134 1.00 407.88 ? 372 GLN B NE2 1 
ATOM 82   N N   . VAL A 1 64  ? 153.788 146.326 156.191 1.00 392.49 ? 373 VAL B N   1 
ATOM 83   C CA  . VAL A 1 64  ? 153.557 145.264 155.219 1.00 392.49 ? 373 VAL B CA  1 
ATOM 84   C C   . VAL A 1 64  ? 152.682 144.178 155.839 1.00 392.49 ? 373 VAL B C   1 
ATOM 85   O O   . VAL A 1 64  ? 151.977 143.451 155.129 1.00 392.49 ? 373 VAL B O   1 
ATOM 86   C CB  . VAL A 1 64  ? 154.892 144.694 154.698 1.00 392.49 ? 373 VAL B CB  1 
ATOM 87   C CG1 . VAL A 1 64  ? 154.657 143.595 153.673 1.00 392.49 ? 373 VAL B CG1 1 
ATOM 88   C CG2 . VAL A 1 64  ? 155.735 145.802 154.086 1.00 392.49 ? 373 VAL B CG2 1 
ATOM 89   N N   . THR A 1 65  ? 152.695 144.077 157.167 1.00 328.77 ? 374 THR B N   1 
ATOM 90   C CA  . THR A 1 65  ? 151.959 143.037 157.886 1.00 328.77 ? 374 THR B CA  1 
ATOM 91   C C   . THR A 1 65  ? 150.811 143.685 158.648 1.00 328.77 ? 374 THR B C   1 
ATOM 92   O O   . THR A 1 65  ? 151.027 144.321 159.684 1.00 328.77 ? 374 THR B O   1 
ATOM 93   C CB  . THR A 1 65  ? 152.871 142.275 158.837 1.00 328.77 ? 374 THR B CB  1 
ATOM 94   O OG1 . THR A 1 65  ? 153.503 143.199 159.730 1.00 328.77 ? 374 THR B OG1 1 
ATOM 95   C CG2 . THR A 1 65  ? 153.927 141.509 158.063 1.00 328.77 ? 374 THR B CG2 1 
ATOM 96   N N   . ASP A 1 66  ? 149.593 143.515 158.140 1.00 276.03 ? 375 ASP B N   1 
ATOM 97   C CA  . ASP A 1 66  ? 148.395 144.018 158.801 1.00 276.03 ? 375 ASP B CA  1 
ATOM 98   C C   . ASP A 1 66  ? 147.422 142.908 159.167 1.00 276.03 ? 375 ASP B C   1 
ATOM 99   O O   . ASP A 1 66  ? 146.983 142.831 160.320 1.00 276.03 ? 375 ASP B O   1 
ATOM 100  C CB  . ASP A 1 66  ? 147.700 145.056 157.905 1.00 276.03 ? 375 ASP B CB  1 
ATOM 101  C CG  . ASP A 1 66  ? 147.434 144.536 156.507 1.00 276.03 ? 375 ASP B CG  1 
ATOM 102  O OD1 . ASP A 1 66  ? 147.835 143.391 156.212 1.00 276.03 ? 375 ASP B OD1 1 
ATOM 103  O OD2 . ASP A 1 66  ? 146.826 145.270 155.703 1.00 276.03 ? 375 ASP B OD2 1 
ATOM 104  N N   . GLU A 1 67  ? 147.082 142.038 158.218 1.00 245.81 ? 376 GLU B N   1 
ATOM 105  C CA  . GLU A 1 67  ? 146.164 140.933 158.449 1.00 245.81 ? 376 GLU B CA  1 
ATOM 106  C C   . GLU A 1 67  ? 146.735 139.603 157.989 1.00 245.81 ? 376 GLU B C   1 
ATOM 107  O O   . GLU A 1 67  ? 146.052 138.578 158.093 1.00 245.81 ? 376 GLU B O   1 
ATOM 108  C CB  . GLU A 1 67  ? 144.839 141.178 157.720 1.00 245.81 ? 376 GLU B CB  1 
ATOM 109  C CG  . GLU A 1 67  ? 145.011 141.447 156.233 1.00 245.81 ? 376 GLU B CG  1 
ATOM 110  C CD  . GLU A 1 67  ? 144.908 140.183 155.400 1.00 245.81 ? 376 GLU B CD  1 
ATOM 111  O OE1 . GLU A 1 67  ? 144.333 139.191 155.895 1.00 245.81 ? 376 GLU B OE1 1 
ATOM 112  O OE2 . GLU A 1 67  ? 145.404 140.181 154.254 1.00 245.81 ? 376 GLU B OE2 1 
ATOM 113  N N   . LEU A 1 68  ? 147.966 139.598 157.484 1.00 263.18 ? 377 LEU B N   1 
ATOM 114  C CA  . LEU A 1 68  ? 148.508 138.451 156.772 1.00 263.18 ? 377 LEU B CA  1 
ATOM 115  C C   . LEU A 1 68  ? 148.681 137.226 157.654 1.00 263.18 ? 377 LEU B C   1 
ATOM 116  O O   . LEU A 1 68  ? 148.492 136.098 157.177 1.00 263.18 ? 377 LEU B O   1 
ATOM 117  C CB  . LEU A 1 68  ? 149.854 138.834 156.165 1.00 263.18 ? 377 LEU B CB  1 
ATOM 118  C CG  . LEU A 1 68  ? 150.483 137.838 155.207 1.00 263.18 ? 377 LEU B CG  1 
ATOM 119  C CD1 . LEU A 1 68  ? 149.659 137.769 153.944 1.00 263.18 ? 377 LEU B CD1 1 
ATOM 120  C CD2 . LEU A 1 68  ? 151.910 138.266 154.913 1.00 263.18 ? 377 LEU B CD2 1 
ATOM 121  N N   . LEU A 1 69  ? 148.987 137.424 158.935 1.00 241.86 ? 378 LEU B N   1 
ATOM 122  C CA  . LEU A 1 69  ? 149.427 136.343 159.805 1.00 241.86 ? 378 LEU B CA  1 
ATOM 123  C C   . LEU A 1 69  ? 148.439 135.184 159.839 1.00 241.86 ? 378 LEU B C   1 
ATOM 124  O O   . LEU A 1 69  ? 148.735 134.150 160.446 1.00 241.86 ? 378 LEU B O   1 
ATOM 125  C CB  . LEU A 1 69  ? 149.675 136.910 161.201 1.00 241.86 ? 378 LEU B CB  1 
ATOM 126  C CG  . LEU A 1 69  ? 151.058 137.557 161.365 1.00 241.86 ? 378 LEU B CG  1 
ATOM 127  C CD1 . LEU A 1 69  ? 151.365 137.868 162.814 1.00 241.86 ? 378 LEU B CD1 1 
ATOM 128  C CD2 . LEU A 1 69  ? 152.159 136.690 160.773 1.00 241.86 ? 378 LEU B CD2 1 
ATOM 129  N N   . GLU A 1 70  ? 147.287 135.339 159.183 1.00 220.62 ? 379 GLU B N   1 
ATOM 130  C CA  . GLU A 1 70  ? 146.297 134.283 159.058 1.00 220.62 ? 379 GLU B CA  1 
ATOM 131  C C   . GLU A 1 70  ? 146.812 133.065 158.296 1.00 220.62 ? 379 GLU B C   1 
ATOM 132  O O   . GLU A 1 70  ? 146.317 131.960 158.539 1.00 220.62 ? 379 GLU B O   1 
ATOM 133  C CB  . GLU A 1 70  ? 145.037 134.859 158.399 1.00 220.62 ? 379 GLU B CB  1 
ATOM 134  C CG  . GLU A 1 70  ? 143.924 133.871 158.113 1.00 220.62 ? 379 GLU B CG  1 
ATOM 135  C CD  . GLU A 1 70  ? 144.066 133.220 156.759 1.00 220.62 ? 379 GLU B CD  1 
ATOM 136  O OE1 . GLU A 1 70  ? 144.013 131.976 156.680 1.00 220.62 ? 379 GLU B OE1 1 
ATOM 137  O OE2 . GLU A 1 70  ? 144.217 133.964 155.769 1.00 220.62 ? 379 GLU B OE2 1 
ATOM 138  N N   . LYS A 1 71  ? 147.773 133.215 157.377 1.00 234.80 ? 380 LYS B N   1 
ATOM 139  C CA  . LYS A 1 71  ? 148.286 132.015 156.714 1.00 234.80 ? 380 LYS B CA  1 
ATOM 140  C C   . LYS A 1 71  ? 149.704 131.611 157.095 1.00 234.80 ? 380 LYS B C   1 
ATOM 141  O O   . LYS A 1 71  ? 150.086 130.468 156.822 1.00 234.80 ? 380 LYS B O   1 
ATOM 142  C CB  . LYS A 1 71  ? 148.207 132.118 155.190 1.00 234.80 ? 380 LYS B CB  1 
ATOM 143  C CG  . LYS A 1 71  ? 146.920 132.691 154.659 1.00 234.80 ? 380 LYS B CG  1 
ATOM 144  C CD  . LYS A 1 71  ? 146.945 132.721 153.139 1.00 234.80 ? 380 LYS B CD  1 
ATOM 145  C CE  . LYS A 1 71  ? 147.294 131.351 152.563 1.00 234.80 ? 380 LYS B CE  1 
ATOM 146  N NZ  . LYS A 1 71  ? 147.483 131.402 151.083 1.00 234.80 ? 380 LYS B NZ  1 
ATOM 147  N N   . ILE A 1 72  ? 150.510 132.499 157.674 1.00 231.01 ? 381 ILE B N   1 
ATOM 148  C CA  . ILE A 1 72  ? 151.782 132.041 158.221 1.00 231.01 ? 381 ILE B CA  1 
ATOM 149  C C   . ILE A 1 72  ? 151.530 130.971 159.262 1.00 231.01 ? 381 ILE B C   1 
ATOM 150  O O   . ILE A 1 72  ? 152.135 129.895 159.234 1.00 231.01 ? 381 ILE B O   1 
ATOM 151  C CB  . ILE A 1 72  ? 152.589 133.208 158.812 1.00 231.01 ? 381 ILE B CB  1 
ATOM 152  C CG1 . ILE A 1 72  ? 152.957 134.221 157.726 1.00 231.01 ? 381 ILE B CG1 1 
ATOM 153  C CG2 . ILE A 1 72  ? 153.819 132.681 159.524 1.00 231.01 ? 381 ILE B CG2 1 
ATOM 154  C CD1 . ILE A 1 72  ? 151.932 135.301 157.505 1.00 231.01 ? 381 ILE B CD1 1 
ATOM 155  N N   . ALA A 1 73  ? 150.628 131.247 160.186 1.00 220.55 ? 382 ALA B N   1 
ATOM 156  C CA  . ALA A 1 73  ? 150.065 130.237 161.061 1.00 220.55 ? 382 ALA B CA  1 
ATOM 157  C C   . ALA A 1 73  ? 148.689 129.870 160.511 1.00 220.55 ? 382 ALA B C   1 
ATOM 158  O O   . ALA A 1 73  ? 147.679 129.987 161.207 1.00 220.55 ? 382 ALA B O   1 
ATOM 159  C CB  . ALA A 1 73  ? 149.990 130.750 162.495 1.00 220.55 ? 382 ALA B CB  1 
ATOM 160  N N   . SER A 1 74  ? 148.654 129.381 159.273 1.00 202.76 ? 383 SER B N   1 
ATOM 161  C CA  . SER A 1 74  ? 147.384 129.026 158.658 1.00 202.76 ? 383 SER B CA  1 
ATOM 162  C C   . SER A 1 74  ? 146.809 127.783 159.304 1.00 202.76 ? 383 SER B C   1 
ATOM 163  O O   . SER A 1 74  ? 145.613 127.738 159.612 1.00 202.76 ? 383 SER B O   1 
ATOM 164  C CB  . SER A 1 74  ? 147.544 128.806 157.147 1.00 202.76 ? 383 SER B CB  1 
ATOM 165  O OG  . SER A 1 74  ? 146.465 128.071 156.614 1.00 202.76 ? 383 SER B OG  1 
ATOM 166  N N   . ARG A 1 75  ? 147.646 126.774 159.525 1.00 254.11 ? 384 ARG B N   1 
ATOM 167  C CA  . ARG A 1 75  ? 147.328 125.634 160.366 1.00 254.11 ? 384 ARG B CA  1 
ATOM 168  C C   . ARG A 1 75  ? 148.217 125.547 161.595 1.00 254.11 ? 384 ARG B C   1 
ATOM 169  O O   . ARG A 1 75  ? 148.224 124.503 162.253 1.00 254.11 ? 384 ARG B O   1 
ATOM 170  C CB  . ARG A 1 75  ? 147.477 124.322 159.576 1.00 254.11 ? 384 ARG B CB  1 
ATOM 171  C CG  . ARG A 1 75  ? 147.721 124.499 158.082 1.00 254.11 ? 384 ARG B CG  1 
ATOM 172  C CD  . ARG A 1 75  ? 147.430 123.228 157.301 1.00 254.11 ? 384 ARG B CD  1 
ATOM 173  N NE  . ARG A 1 75  ? 148.346 123.057 156.179 1.00 254.11 ? 384 ARG B NE  1 
ATOM 174  C CZ  . ARG A 1 75  ? 148.403 123.865 155.129 1.00 254.11 ? 384 ARG B CZ  1 
ATOM 175  N N   . SER A 1 76  ? 149.002 126.580 161.895 1.00 261.74 ? 385 SER B N   1 
ATOM 176  C CA  . SER A 1 76  ? 150.148 126.387 162.773 1.00 261.74 ? 385 SER B CA  1 
ATOM 177  C C   . SER A 1 76  ? 149.744 126.254 164.228 1.00 261.74 ? 385 SER B C   1 
ATOM 178  O O   . SER A 1 76  ? 148.809 126.898 164.709 1.00 261.74 ? 385 SER B O   1 
ATOM 179  C CB  . SER A 1 76  ? 151.149 127.530 162.660 1.00 261.74 ? 385 SER B CB  1 
ATOM 180  O OG  . SER A 1 76  ? 151.729 127.590 161.372 1.00 261.74 ? 385 SER B OG  1 
ATOM 181  N N   . GLN A 1 77  ? 150.494 125.415 164.930 1.00 275.04 ? 386 GLN B N   1 
ATOM 182  C CA  . GLN A 1 77  ? 150.349 125.232 166.358 1.00 275.04 ? 386 GLN B CA  1 
ATOM 183  C C   . GLN A 1 77  ? 151.673 125.250 167.113 1.00 275.04 ? 386 GLN B C   1 
ATOM 184  O O   . GLN A 1 77  ? 151.708 124.775 168.251 1.00 275.04 ? 386 GLN B O   1 
ATOM 185  C CB  . GLN A 1 77  ? 149.617 123.912 166.652 1.00 275.04 ? 386 GLN B CB  1 
ATOM 186  C CG  . GLN A 1 77  ? 148.096 123.932 166.441 1.00 275.04 ? 386 GLN B CG  1 
ATOM 187  C CD  . GLN A 1 77  ? 147.665 124.007 164.984 1.00 275.04 ? 386 GLN B CD  1 
ATOM 188  O OE1 . GLN A 1 77  ? 146.966 124.935 164.578 1.00 275.04 ? 386 GLN B OE1 1 
ATOM 189  N NE2 . GLN A 1 77  ? 148.089 123.036 164.189 1.00 275.04 ? 386 GLN B NE2 1 
ATOM 190  N N   . ASN A 1 78  ? 152.764 125.743 166.518 1.00 309.34 ? 387 ASN B N   1 
ATOM 191  C CA  . ASN A 1 78  ? 154.044 125.740 167.219 1.00 309.34 ? 387 ASN B CA  1 
ATOM 192  C C   . ASN A 1 78  ? 154.918 126.953 166.905 1.00 309.34 ? 387 ASN B C   1 
ATOM 193  O O   . ASN A 1 78  ? 156.117 126.800 166.649 1.00 309.34 ? 387 ASN B O   1 
ATOM 194  C CB  . ASN A 1 78  ? 154.817 124.457 166.900 1.00 309.34 ? 387 ASN B CB  1 
ATOM 195  C CG  . ASN A 1 78  ? 154.967 124.216 165.408 1.00 309.34 ? 387 ASN B CG  1 
ATOM 196  O OD1 . ASN A 1 78  ? 154.506 125.009 164.589 1.00 309.34 ? 387 ASN B OD1 1 
ATOM 197  N ND2 . ASN A 1 78  ? 155.627 123.120 165.051 1.00 309.34 ? 387 ASN B ND2 1 
ATOM 198  N N   . ILE A 1 79  ? 154.349 128.156 166.930 1.00 326.04 ? 388 ILE B N   1 
ATOM 199  C CA  . ILE A 1 79  ? 155.123 129.369 166.675 1.00 326.04 ? 388 ILE B CA  1 
ATOM 200  C C   . ILE A 1 79  ? 155.920 129.705 167.935 1.00 326.04 ? 388 ILE B C   1 
ATOM 201  O O   . ILE A 1 79  ? 155.346 129.845 169.017 1.00 326.04 ? 388 ILE B O   1 
ATOM 202  C CB  . ILE A 1 79  ? 154.221 130.534 166.260 1.00 326.04 ? 388 ILE B CB  1 
ATOM 203  C CG1 . ILE A 1 79  ? 153.238 130.082 165.178 1.00 326.04 ? 388 ILE B CG1 1 
ATOM 204  C CG2 . ILE A 1 79  ? 155.057 131.704 165.773 1.00 326.04 ? 388 ILE B CG2 1 
ATOM 205  C CD1 . ILE A 1 79  ? 153.888 129.805 163.839 1.00 326.04 ? 388 ILE B CD1 1 
ATOM 206  N N   . ILE A 1 80  ? 157.245 129.810 167.806 1.00 349.32 ? 389 ILE B N   1 
ATOM 207  C CA  . ILE A 1 80  ? 158.111 130.003 168.968 1.00 349.32 ? 389 ILE B CA  1 
ATOM 208  C C   . ILE A 1 80  ? 159.172 131.077 168.740 1.00 349.32 ? 389 ILE B C   1 
ATOM 209  O O   . ILE A 1 80  ? 160.014 131.318 169.613 1.00 349.32 ? 389 ILE B O   1 
ATOM 210  C CB  . ILE A 1 80  ? 158.783 128.675 169.371 1.00 349.32 ? 389 ILE B CB  1 
ATOM 211  C CG1 . ILE A 1 80  ? 159.611 128.118 168.213 1.00 349.32 ? 389 ILE B CG1 1 
ATOM 212  C CG2 . ILE A 1 80  ? 157.752 127.656 169.830 1.00 349.32 ? 389 ILE B CG2 1 
ATOM 213  C CD1 . ILE A 1 80  ? 160.473 126.942 168.601 1.00 349.32 ? 389 ILE B CD1 1 
ATOM 214  N N   . GLU A 1 81  ? 159.149 131.733 167.582 1.00 371.28 ? 390 GLU B N   1 
ATOM 215  C CA  . GLU A 1 81  ? 160.205 132.670 167.197 1.00 371.28 ? 390 GLU B CA  1 
ATOM 216  C C   . GLU A 1 81  ? 159.612 133.996 166.729 1.00 371.28 ? 390 GLU B C   1 
ATOM 217  O O   . GLU A 1 81  ? 159.970 134.528 165.675 1.00 371.28 ? 390 GLU B O   1 
ATOM 218  C CB  . GLU A 1 81  ? 161.092 132.058 166.116 1.00 371.28 ? 390 GLU B CB  1 
ATOM 219  C CG  . GLU A 1 81  ? 162.459 132.719 165.943 1.00 371.28 ? 390 GLU B CG  1 
ATOM 220  C CD  . GLU A 1 81  ? 163.405 132.448 167.096 1.00 371.28 ? 390 GLU B CD  1 
ATOM 221  O OE1 . GLU A 1 81  ? 163.262 131.394 167.749 1.00 371.28 ? 390 GLU B OE1 1 
ATOM 222  O OE2 . GLU A 1 81  ? 164.294 133.289 167.346 1.00 371.28 ? 390 GLU B OE2 1 
ATOM 223  N N   . ILE A 1 82  ? 158.689 134.556 167.506 1.00 349.43 ? 391 ILE B N   1 
ATOM 224  C CA  . ILE A 1 82  ? 158.056 135.821 167.138 1.00 349.43 ? 391 ILE B CA  1 
ATOM 225  C C   . ILE A 1 82  ? 159.006 136.960 167.492 1.00 349.43 ? 391 ILE B C   1 
ATOM 226  O O   . ILE A 1 82  ? 159.252 137.238 168.669 1.00 349.43 ? 391 ILE B O   1 
ATOM 227  C CB  . ILE A 1 82  ? 156.698 136.002 167.824 1.00 349.43 ? 391 ILE B CB  1 
ATOM 228  C CG1 . ILE A 1 82  ? 155.669 135.031 167.252 1.00 349.43 ? 391 ILE B CG1 1 
ATOM 229  C CG2 . ILE A 1 82  ? 156.197 137.423 167.642 1.00 349.43 ? 391 ILE B CG2 1 
ATOM 230  C CD1 . ILE A 1 82  ? 154.278 135.238 167.803 1.00 349.43 ? 391 ILE B CD1 1 
ATOM 231  N N   . ASN A 1 83  ? 159.535 137.632 166.469 1.00 344.79 ? 392 ASN B N   1 
ATOM 232  C CA  . ASN A 1 83  ? 160.353 138.837 166.633 1.00 344.79 ? 392 ASN B CA  1 
ATOM 233  C C   . ASN A 1 83  ? 159.821 139.842 165.615 1.00 344.79 ? 392 ASN B C   1 
ATOM 234  O O   . ASN A 1 83  ? 160.049 139.703 164.411 1.00 344.79 ? 392 ASN B O   1 
ATOM 235  C CB  . ASN A 1 83  ? 161.836 138.552 166.436 1.00 344.79 ? 392 ASN B CB  1 
ATOM 236  C CG  . ASN A 1 83  ? 162.720 139.705 166.886 1.00 344.79 ? 392 ASN B CG  1 
ATOM 237  O OD1 . ASN A 1 83  ? 162.351 140.872 166.765 1.00 344.79 ? 392 ASN B OD1 1 
ATOM 238  N ND2 . ASN A 1 83  ? 163.898 139.378 167.405 1.00 344.79 ? 392 ASN B ND2 1 
ATOM 239  N N   . ILE A 1 84  ? 159.105 140.847 166.106 1.00 329.47 ? 393 ILE B N   1 
ATOM 240  C CA  . ILE A 1 84  ? 158.454 141.826 165.245 1.00 329.47 ? 393 ILE B CA  1 
ATOM 241  C C   . ILE A 1 84  ? 159.087 143.186 165.517 1.00 329.47 ? 393 ILE B C   1 
ATOM 242  O O   . ILE A 1 84  ? 158.422 144.225 165.437 1.00 329.47 ? 393 ILE B O   1 
ATOM 243  C CB  . ILE A 1 84  ? 156.932 141.838 165.480 1.00 329.47 ? 393 ILE B CB  1 
ATOM 244  C CG1 . ILE A 1 84  ? 156.398 140.408 165.550 1.00 329.47 ? 393 ILE B CG1 1 
ATOM 245  C CG2 . ILE A 1 84  ? 156.215 142.539 164.348 1.00 329.47 ? 393 ILE B CG2 1 
ATOM 246  C CD1 . ILE A 1 84  ? 154.888 140.318 165.591 1.00 329.47 ? 393 ILE B CD1 1 
ATOM 247  N N   . SER A 1 85  ? 160.377 143.188 165.844 1.00 316.85 ? 394 SER B N   1 
ATOM 248  C CA  . SER A 1 85  ? 161.044 144.407 166.281 1.00 316.85 ? 394 SER B CA  1 
ATOM 249  C C   . SER A 1 85  ? 160.985 145.483 165.202 1.00 316.85 ? 394 SER B C   1 
ATOM 250  O O   . SER A 1 85  ? 161.042 145.200 164.002 1.00 316.85 ? 394 SER B O   1 
ATOM 251  C CB  . SER A 1 85  ? 162.497 144.117 166.656 1.00 316.85 ? 394 SER B CB  1 
ATOM 252  O OG  . SER A 1 85  ? 163.269 143.789 165.519 1.00 316.85 ? 394 SER B OG  1 
ATOM 253  N N   . ASP A 1 86  ? 160.864 146.734 165.655 1.00 286.06 ? 395 ASP B N   1 
ATOM 254  C CA  . ASP A 1 86  ? 160.629 147.886 164.784 1.00 286.06 ? 395 ASP B CA  1 
ATOM 255  C C   . ASP A 1 86  ? 159.360 147.706 163.951 1.00 286.06 ? 395 ASP B C   1 
ATOM 256  O O   . ASP A 1 86  ? 159.306 148.074 162.776 1.00 286.06 ? 395 ASP B O   1 
ATOM 257  C CB  . ASP A 1 86  ? 161.839 148.169 163.893 1.00 286.06 ? 395 ASP B CB  1 
ATOM 258  C CG  . ASP A 1 86  ? 163.030 148.672 164.681 1.00 286.06 ? 395 ASP B CG  1 
ATOM 259  O OD1 . ASP A 1 86  ? 163.006 149.843 165.111 1.00 286.06 ? 395 ASP B OD1 1 
ATOM 260  O OD2 . ASP A 1 86  ? 163.985 147.896 164.879 1.00 286.06 ? 395 ASP B OD2 1 
ATOM 261  N N   . CYS A 1 87  ? 158.328 147.137 164.569 1.00 324.25 ? 396 CYS B N   1 
ATOM 262  C CA  . CYS A 1 87  ? 157.034 147.029 163.911 1.00 324.25 ? 396 CYS B CA  1 
ATOM 263  C C   . CYS A 1 87  ? 156.382 148.399 163.826 1.00 324.25 ? 396 CYS B C   1 
ATOM 264  O O   . CYS A 1 87  ? 156.504 149.223 164.737 1.00 324.25 ? 396 CYS B O   1 
ATOM 265  C CB  . CYS A 1 87  ? 156.119 146.068 164.663 1.00 324.25 ? 396 CYS B CB  1 
ATOM 266  S SG  . CYS A 1 87  ? 155.412 146.727 166.190 1.00 324.25 ? 396 CYS B SG  1 
ATOM 267  N N   . ARG A 1 88  ? 155.699 148.649 162.715 1.00 345.06 ? 397 ARG B N   1 
ATOM 268  C CA  . ARG A 1 88  ? 155.022 149.923 162.536 1.00 345.06 ? 397 ARG B CA  1 
ATOM 269  C C   . ARG A 1 88  ? 153.680 149.783 161.824 1.00 345.06 ? 397 ARG B C   1 
ATOM 270  O O   . ARG A 1 88  ? 153.130 150.794 161.370 1.00 345.06 ? 397 ARG B O   1 
ATOM 271  C CB  . ARG A 1 88  ? 155.935 150.889 161.774 1.00 345.06 ? 397 ARG B CB  1 
ATOM 272  C CG  . ARG A 1 88  ? 156.020 152.280 162.377 1.00 345.06 ? 397 ARG B CG  1 
ATOM 273  C CD  . ARG A 1 88  ? 156.953 152.315 163.579 1.00 345.06 ? 397 ARG B CD  1 
ATOM 274  N NE  . ARG A 1 88  ? 156.224 152.474 164.831 1.00 345.06 ? 397 ARG B NE  1 
ATOM 275  C CZ  . ARG A 1 88  ? 156.610 153.259 165.828 1.00 345.06 ? 397 ARG B CZ  1 
ATOM 276  N N   . SER A 1 89  ? 153.133 148.572 161.712 1.00 348.90 ? 398 SER B N   1 
ATOM 277  C CA  . SER A 1 89  ? 151.941 148.322 160.911 1.00 348.90 ? 398 SER B CA  1 
ATOM 278  C C   . SER A 1 89  ? 150.746 147.876 161.735 1.00 348.90 ? 398 SER B C   1 
ATOM 279  O O   . SER A 1 89  ? 149.676 148.491 161.649 1.00 348.90 ? 398 SER B O   1 
ATOM 280  C CB  . SER A 1 89  ? 152.247 147.261 159.844 1.00 348.90 ? 398 SER B CB  1 
ATOM 281  O OG  . SER A 1 89  ? 151.153 147.076 158.966 1.00 348.90 ? 398 SER B OG  1 
ATOM 282  N N   . MET A 1 90  ? 150.888 146.819 162.526 1.00 348.51 ? 399 MET B N   1 
ATOM 283  C CA  . MET A 1 90  ? 149.740 146.236 163.201 1.00 348.51 ? 399 MET B CA  1 
ATOM 284  C C   . MET A 1 90  ? 149.285 147.104 164.369 1.00 348.51 ? 399 MET B C   1 
ATOM 285  O O   . MET A 1 90  ? 149.996 147.996 164.839 1.00 348.51 ? 399 MET B O   1 
ATOM 286  C CB  . MET A 1 90  ? 150.061 144.824 163.689 1.00 348.51 ? 399 MET B CB  1 
ATOM 287  C CG  . MET A 1 90  ? 151.087 144.767 164.803 1.00 348.51 ? 399 MET B CG  1 
ATOM 288  S SD  . MET A 1 90  ? 152.761 144.732 164.141 1.00 348.51 ? 399 MET B SD  1 
ATOM 289  C CE  . MET A 1 90  ? 152.790 143.090 163.429 1.00 348.51 ? 399 MET B CE  1 
ATOM 290  N N   . SER A 1 91  ? 148.073 146.816 164.841 1.00 364.03 ? 400 SER B N   1 
ATOM 291  C CA  . SER A 1 91  ? 147.472 147.538 165.954 1.00 364.03 ? 400 SER B CA  1 
ATOM 292  C C   . SER A 1 91  ? 147.093 146.556 167.053 1.00 364.03 ? 400 SER B C   1 
ATOM 293  O O   . SER A 1 91  ? 147.482 145.384 167.002 1.00 364.03 ? 400 SER B O   1 
ATOM 294  C CB  . SER A 1 91  ? 146.241 148.325 165.495 1.00 364.03 ? 400 SER B CB  1 
ATOM 295  O OG  . SER A 1 91  ? 145.354 147.501 164.757 1.00 364.03 ? 400 SER B OG  1 
ATOM 296  N N   . ASP A 1 92  ? 146.344 147.026 168.053 1.00 384.45 ? 401 ASP B N   1 
ATOM 297  C CA  . ASP A 1 92  ? 145.928 146.148 169.141 1.00 384.45 ? 401 ASP B CA  1 
ATOM 298  C C   . ASP A 1 92  ? 145.124 144.968 168.610 1.00 384.45 ? 401 ASP B C   1 
ATOM 299  O O   . ASP A 1 92  ? 145.286 143.832 169.071 1.00 384.45 ? 401 ASP B O   1 
ATOM 300  C CB  . ASP A 1 92  ? 145.123 146.935 170.172 1.00 384.45 ? 401 ASP B CB  1 
ATOM 301  C CG  . ASP A 1 92  ? 144.598 146.059 171.288 1.00 384.45 ? 401 ASP B CG  1 
ATOM 302  O OD1 . ASP A 1 92  ? 145.421 145.558 172.082 1.00 384.45 ? 401 ASP B OD1 1 
ATOM 303  O OD2 . ASP A 1 92  ? 143.366 145.877 171.376 1.00 384.45 ? 401 ASP B OD2 1 
ATOM 304  N N   . ASN A 1 93  ? 144.253 145.222 167.633 1.00 406.03 ? 402 ASN B N   1 
ATOM 305  C CA  . ASN A 1 93  ? 143.582 144.126 166.945 1.00 406.03 ? 402 ASN B CA  1 
ATOM 306  C C   . ASN A 1 93  ? 144.598 143.223 166.255 1.00 406.03 ? 402 ASN B C   1 
ATOM 307  O O   . ASN A 1 93  ? 144.461 141.991 166.270 1.00 406.03 ? 402 ASN B O   1 
ATOM 308  C CB  . ASN A 1 93  ? 142.573 144.683 165.936 1.00 406.03 ? 402 ASN B CB  1 
ATOM 309  C CG  . ASN A 1 93  ? 141.489 143.682 165.575 1.00 406.03 ? 402 ASN B CG  1 
ATOM 310  O OD1 . ASN A 1 93  ? 141.492 142.545 166.044 1.00 406.03 ? 402 ASN B OD1 1 
ATOM 311  N ND2 . ASN A 1 93  ? 140.551 144.106 164.735 1.00 406.03 ? 402 ASN B ND2 1 
ATOM 312  N N   . GLY A 1 94  ? 145.638 143.822 165.669 1.00 412.50 ? 403 GLY B N   1 
ATOM 313  C CA  . GLY A 1 94  ? 146.638 143.070 164.934 1.00 412.50 ? 403 GLY B CA  1 
ATOM 314  C C   . GLY A 1 94  ? 147.469 142.134 165.784 1.00 412.50 ? 403 GLY B C   1 
ATOM 315  O O   . GLY A 1 94  ? 148.103 141.224 165.241 1.00 412.50 ? 403 GLY B O   1 
ATOM 316  N N   . VAL A 1 95  ? 147.493 142.337 167.100 1.00 403.74 ? 404 VAL B N   1 
ATOM 317  C CA  . VAL A 1 95  ? 148.204 141.422 167.985 1.00 403.74 ? 404 VAL B CA  1 
ATOM 318  C C   . VAL A 1 95  ? 147.198 140.515 168.682 1.00 403.74 ? 404 VAL B C   1 
ATOM 319  O O   . VAL A 1 95  ? 147.504 139.360 169.003 1.00 403.74 ? 404 VAL B O   1 
ATOM 320  C CB  . VAL A 1 95  ? 149.080 142.176 169.005 1.00 403.74 ? 404 VAL B CB  1 
ATOM 321  C CG1 . VAL A 1 95  ? 148.224 142.948 169.993 1.00 403.74 ? 404 VAL B CG1 1 
ATOM 322  C CG2 . VAL A 1 95  ? 150.006 141.210 169.733 1.00 403.74 ? 404 VAL B CG2 1 
ATOM 323  N N   . CYS A 1 96  ? 145.979 141.019 168.900 1.00 418.24 ? 405 CYS B N   1 
ATOM 324  C CA  . CYS A 1 96  ? 144.983 140.224 169.607 1.00 418.24 ? 405 CYS B CA  1 
ATOM 325  C C   . CYS A 1 96  ? 144.423 139.107 168.742 1.00 418.24 ? 405 CYS B C   1 
ATOM 326  O O   . CYS A 1 96  ? 143.955 138.099 169.283 1.00 418.24 ? 405 CYS B O   1 
ATOM 327  C CB  . CYS A 1 96  ? 143.836 141.104 170.099 1.00 418.24 ? 405 CYS B CB  1 
ATOM 328  S SG  . CYS A 1 96  ? 142.572 141.426 168.856 1.00 418.24 ? 405 CYS B SG  1 
ATOM 329  N N   . VAL A 1 97  ? 144.441 139.267 167.416 1.00 423.75 ? 406 VAL B N   1 
ATOM 330  C CA  . VAL A 1 97  ? 143.977 138.189 166.547 1.00 423.75 ? 406 VAL B CA  1 
ATOM 331  C C   . VAL A 1 97  ? 144.873 136.961 166.691 1.00 423.75 ? 406 VAL B C   1 
ATOM 332  O O   . VAL A 1 97  ? 144.386 135.827 166.774 1.00 423.75 ? 406 VAL B O   1 
ATOM 333  C CB  . VAL A 1 97  ? 143.891 138.668 165.085 1.00 423.75 ? 406 VAL B CB  1 
ATOM 334  C CG1 . VAL A 1 97  ? 142.692 139.588 164.903 1.00 423.75 ? 406 VAL B CG1 1 
ATOM 335  C CG2 . VAL A 1 97  ? 145.181 139.358 164.660 1.00 423.75 ? 406 VAL B CG2 1 
ATOM 336  N N   . LEU A 1 98  ? 146.194 137.165 166.723 1.00 410.51 ? 407 LEU B N   1 
ATOM 337  C CA  . LEU A 1 98  ? 147.117 136.051 166.929 1.00 410.51 ? 407 LEU B CA  1 
ATOM 338  C C   . LEU A 1 98  ? 147.141 135.601 168.383 1.00 410.51 ? 407 LEU B C   1 
ATOM 339  O O   . LEU A 1 98  ? 147.380 134.421 168.665 1.00 410.51 ? 407 LEU B O   1 
ATOM 340  C CB  . LEU A 1 98  ? 148.527 136.435 166.475 1.00 410.51 ? 407 LEU B CB  1 
ATOM 341  C CG  . LEU A 1 98  ? 149.532 135.281 166.389 1.00 410.51 ? 407 LEU B CG  1 
ATOM 342  C CD1 . LEU A 1 98  ? 150.450 135.453 165.202 1.00 410.51 ? 407 LEU B CD1 1 
ATOM 343  C CD2 . LEU A 1 98  ? 150.355 135.173 167.664 1.00 410.51 ? 407 LEU B CD2 1 
ATOM 344  N N   . ALA A 1 99  ? 146.895 136.520 169.317 1.00 396.62 ? 408 ALA B N   1 
ATOM 345  C CA  . ALA A 1 99  ? 147.006 136.188 170.730 1.00 396.62 ? 408 ALA B CA  1 
ATOM 346  C C   . ALA A 1 99  ? 145.890 135.272 171.212 1.00 396.62 ? 408 ALA B C   1 
ATOM 347  O O   . ALA A 1 99  ? 145.940 134.806 172.354 1.00 396.62 ? 408 ALA B O   1 
ATOM 348  C CB  . ALA A 1 99  ? 147.032 137.466 171.563 1.00 396.62 ? 408 ALA B CB  1 
ATOM 349  N N   . PHE A 1 100 ? 144.882 135.007 170.374 1.00 387.11 ? 409 PHE B N   1 
ATOM 350  C CA  . PHE A 1 100 ? 143.772 134.155 170.791 1.00 387.11 ? 409 PHE B CA  1 
ATOM 351  C C   . PHE A 1 100 ? 144.255 132.762 171.181 1.00 387.11 ? 409 PHE B C   1 
ATOM 352  O O   . PHE A 1 100 ? 143.826 132.211 172.201 1.00 387.11 ? 409 PHE B O   1 
ATOM 353  C CB  . PHE A 1 100 ? 142.735 134.061 169.669 1.00 387.11 ? 409 PHE B CB  1 
ATOM 354  C CG  . PHE A 1 100 ? 141.351 133.700 170.139 1.00 387.11 ? 409 PHE B CG  1 
ATOM 355  C CD1 . PHE A 1 100 ? 140.721 134.439 171.125 1.00 387.11 ? 409 PHE B CD1 1 
ATOM 356  C CD2 . PHE A 1 100 ? 140.683 132.616 169.594 1.00 387.11 ? 409 PHE B CD2 1 
ATOM 357  C CE1 . PHE A 1 100 ? 139.447 134.107 171.553 1.00 387.11 ? 409 PHE B CE1 1 
ATOM 358  C CE2 . PHE A 1 100 ? 139.411 132.278 170.022 1.00 387.11 ? 409 PHE B CE2 1 
ATOM 359  C CZ  . PHE A 1 100 ? 138.792 133.025 171.002 1.00 387.11 ? 409 PHE B CZ  1 
ATOM 360  N N   . LYS A 1 101 ? 145.149 132.176 170.384 1.00 391.08 ? 410 LYS B N   1 
ATOM 361  C CA  . LYS A 1 101 ? 145.626 130.817 170.621 1.00 391.08 ? 410 LYS B CA  1 
ATOM 362  C C   . LYS A 1 101 ? 146.921 130.799 171.426 1.00 391.08 ? 410 LYS B C   1 
ATOM 363  O O   . LYS A 1 101 ? 146.975 130.201 172.504 1.00 391.08 ? 410 LYS B O   1 
ATOM 364  C CB  . LYS A 1 101 ? 145.822 130.082 169.285 1.00 391.08 ? 410 LYS B CB  1 
ATOM 365  C CG  . LYS A 1 101 ? 144.657 130.193 168.304 1.00 391.08 ? 410 LYS B CG  1 
ATOM 366  C CD  . LYS A 1 101 ? 143.290 130.007 168.968 1.00 391.08 ? 410 LYS B CD  1 
ATOM 367  C CE  . LYS A 1 101 ? 143.060 128.574 169.431 1.00 391.08 ? 410 LYS B CE  1 
ATOM 368  N NZ  . LYS A 1 101 ? 141.785 128.442 170.191 1.00 391.08 ? 410 LYS B NZ  1 
ATOM 369  N N   . CYS A 1 102 ? 147.966 131.458 170.918 1.00 360.97 ? 411 CYS B N   1 
ATOM 370  C CA  . CYS A 1 102 ? 149.301 131.474 171.508 1.00 360.97 ? 411 CYS B CA  1 
ATOM 371  C C   . CYS A 1 102 ? 149.807 130.065 171.790 1.00 360.97 ? 411 CYS B C   1 
ATOM 372  O O   . CYS A 1 102 ? 149.917 129.669 172.957 1.00 360.97 ? 411 CYS B O   1 
ATOM 373  C CB  . CYS A 1 102 ? 149.312 132.293 172.798 1.00 360.97 ? 411 CYS B CB  1 
ATOM 374  S SG  . CYS A 1 102 ? 149.010 134.049 172.567 1.00 360.97 ? 411 CYS B SG  1 
ATOM 375  N N   . PRO A 1 103 ? 150.125 129.277 170.764 1.00 337.85 ? 412 PRO B N   1 
ATOM 376  C CA  . PRO A 1 103 ? 150.580 127.907 171.022 1.00 337.85 ? 412 PRO B CA  1 
ATOM 377  C C   . PRO A 1 103 ? 152.036 127.849 171.454 1.00 337.85 ? 412 PRO B C   1 
ATOM 378  O O   . PRO A 1 103 ? 152.939 127.906 170.613 1.00 337.85 ? 412 PRO B O   1 
ATOM 379  C CB  . PRO A 1 103 ? 150.374 127.207 169.669 1.00 337.85 ? 412 PRO B CB  1 
ATOM 380  C CG  . PRO A 1 103 ? 149.706 128.224 168.762 1.00 337.85 ? 412 PRO B CG  1 
ATOM 381  C CD  . PRO A 1 103 ? 150.044 129.560 169.324 1.00 337.85 ? 412 PRO B CD  1 
ATOM 382  N N   . GLY A 1 104 ? 152.273 127.722 172.758 1.00 314.00 ? 413 GLY B N   1 
ATOM 383  C CA  . GLY A 1 104 ? 153.603 127.468 173.281 1.00 314.00 ? 413 GLY B CA  1 
ATOM 384  C C   . GLY A 1 104 ? 154.681 128.456 172.879 1.00 314.00 ? 413 GLY B C   1 
ATOM 385  O O   . GLY A 1 104 ? 155.792 128.047 172.529 1.00 314.00 ? 413 GLY B O   1 
ATOM 386  N N   . LEU A 1 105 ? 154.382 129.752 172.930 1.00 304.59 ? 414 LEU B N   1 
ATOM 387  C CA  . LEU A 1 105 ? 155.367 130.758 172.559 1.00 304.59 ? 414 LEU B CA  1 
ATOM 388  C C   . LEU A 1 105 ? 156.563 130.719 173.501 1.00 304.59 ? 414 LEU B C   1 
ATOM 389  O O   . LEU A 1 105 ? 156.424 130.468 174.701 1.00 304.59 ? 414 LEU B O   1 
ATOM 390  C CB  . LEU A 1 105 ? 154.741 132.152 172.562 1.00 304.59 ? 414 LEU B CB  1 
ATOM 391  C CG  . LEU A 1 105 ? 153.973 132.590 171.312 1.00 304.59 ? 414 LEU B CG  1 
ATOM 392  C CD1 . LEU A 1 105 ? 154.935 132.667 170.146 1.00 304.59 ? 414 LEU B CD1 1 
ATOM 393  C CD2 . LEU A 1 105 ? 152.818 131.664 170.976 1.00 304.59 ? 414 LEU B CD2 1 
ATOM 394  N N   . LEU A 1 106 ? 157.751 130.957 172.945 1.00 288.30 ? 415 LEU B N   1 
ATOM 395  C CA  . LEU A 1 106 ? 158.975 130.839 173.727 1.00 288.30 ? 415 LEU B CA  1 
ATOM 396  C C   . LEU A 1 106 ? 159.832 132.096 173.662 1.00 288.30 ? 415 LEU B C   1 
ATOM 397  O O   . LEU A 1 106 ? 160.418 132.501 174.670 1.00 288.30 ? 415 LEU B O   1 
ATOM 398  C CB  . LEU A 1 106 ? 159.784 129.633 173.251 1.00 288.30 ? 415 LEU B CB  1 
ATOM 399  C CG  . LEU A 1 106 ? 159.063 128.287 173.330 1.00 288.30 ? 415 LEU B CG  1 
ATOM 400  C CD1 . LEU A 1 106 ? 159.969 127.157 172.870 1.00 288.30 ? 415 LEU B CD1 1 
ATOM 401  C CD2 . LEU A 1 106 ? 158.574 128.044 174.739 1.00 288.30 ? 415 LEU B CD2 1 
ATOM 402  N N   . ARG A 1 107 ? 159.904 132.731 172.497 1.00 275.05 ? 416 ARG B N   1 
ATOM 403  C CA  . ARG A 1 107 ? 160.804 133.862 172.280 1.00 275.05 ? 416 ARG B CA  1 
ATOM 404  C C   . ARG A 1 107 ? 160.036 135.075 171.773 1.00 275.05 ? 416 ARG B C   1 
ATOM 405  O O   . ARG A 1 107 ? 160.399 135.698 170.774 1.00 275.05 ? 416 ARG B O   1 
ATOM 406  C CB  . ARG A 1 107 ? 161.934 133.504 171.315 1.00 275.05 ? 416 ARG B CB  1 
ATOM 407  C CG  . ARG A 1 107 ? 163.236 133.090 171.995 1.00 275.05 ? 416 ARG B CG  1 
ATOM 408  C CD  . ARG A 1 107 ? 163.845 131.852 171.358 1.00 275.05 ? 416 ARG B CD  1 
ATOM 409  N NE  . ARG A 1 107 ? 164.138 130.815 172.341 1.00 275.05 ? 416 ARG B NE  1 
ATOM 410  C CZ  . ARG A 1 107 ? 165.177 129.994 172.274 1.00 275.05 ? 416 ARG B CZ  1 
ATOM 411  N N   . TYR A 1 108 ? 158.947 135.420 172.457 1.00 257.53 ? 417 TYR B N   1 
ATOM 412  C CA  . TYR A 1 108 ? 158.228 136.648 172.137 1.00 257.53 ? 417 TYR B CA  1 
ATOM 413  C C   . TYR A 1 108 ? 159.123 137.862 172.356 1.00 257.53 ? 417 TYR B C   1 
ATOM 414  O O   . TYR A 1 108 ? 159.804 137.975 173.379 1.00 257.53 ? 417 TYR B O   1 
ATOM 415  C CB  . TYR A 1 108 ? 156.964 136.759 172.986 1.00 257.53 ? 417 TYR B CB  1 
ATOM 416  C CG  . TYR A 1 108 ? 156.213 138.053 172.774 1.00 257.53 ? 417 TYR B CG  1 
ATOM 417  C CD1 . TYR A 1 108 ? 155.432 138.247 171.643 1.00 257.53 ? 417 TYR B CD1 1 
ATOM 418  C CD2 . TYR A 1 108 ? 156.280 139.077 173.707 1.00 257.53 ? 417 TYR B CD2 1 
ATOM 419  C CE1 . TYR A 1 108 ? 154.745 139.428 171.445 1.00 257.53 ? 417 TYR B CE1 1 
ATOM 420  C CE2 . TYR A 1 108 ? 155.594 140.261 173.518 1.00 257.53 ? 417 TYR B CE2 1 
ATOM 421  C CZ  . TYR A 1 108 ? 154.829 140.430 172.387 1.00 257.53 ? 417 TYR B CZ  1 
ATOM 422  N N   . THR A 1 109 ? 159.119 138.774 171.386 1.00 265.94 ? 418 THR B N   1 
ATOM 423  C CA  . THR A 1 109 ? 160.008 139.931 171.392 1.00 265.94 ? 418 THR B CA  1 
ATOM 424  C C   . THR A 1 109 ? 159.426 141.003 170.483 1.00 265.94 ? 418 THR B C   1 
ATOM 425  O O   . THR A 1 109 ? 158.940 140.690 169.393 1.00 265.94 ? 418 THR B O   1 
ATOM 426  C CB  . THR A 1 109 ? 161.419 139.537 170.931 1.00 265.94 ? 418 THR B CB  1 
ATOM 427  O OG1 . THR A 1 109 ? 161.955 138.540 171.809 1.00 265.94 ? 418 THR B OG1 1 
ATOM 428  C CG2 . THR A 1 109 ? 162.349 140.740 170.895 1.00 265.94 ? 418 THR B CG2 1 
ATOM 429  N N   . ALA A 1 110 ? 159.470 142.259 170.932 1.00 255.54 ? 419 ALA B N   1 
ATOM 430  C CA  . ALA A 1 110 ? 159.015 143.381 170.110 1.00 255.54 ? 419 ALA B CA  1 
ATOM 431  C C   . ALA A 1 110 ? 159.764 144.631 170.566 1.00 255.54 ? 419 ALA B C   1 
ATOM 432  O O   . ALA A 1 110 ? 159.399 145.239 171.576 1.00 255.54 ? 419 ALA B O   1 
ATOM 433  C CB  . ALA A 1 110 ? 157.506 143.562 170.212 1.00 255.54 ? 419 ALA B CB  1 
ATOM 434  N N   . TYR A 1 111 ? 160.789 145.017 169.810 1.00 259.67 ? 420 TYR B N   1 
ATOM 435  C CA  . TYR A 1 111 ? 161.567 146.213 170.098 1.00 259.67 ? 420 TYR B CA  1 
ATOM 436  C C   . TYR A 1 111 ? 160.905 147.433 169.478 1.00 259.67 ? 420 TYR B C   1 
ATOM 437  O O   . TYR A 1 111 ? 160.482 147.402 168.320 1.00 259.67 ? 420 TYR B O   1 
ATOM 438  C CB  . TYR A 1 111 ? 162.997 146.106 169.561 1.00 259.67 ? 420 TYR B CB  1 
ATOM 439  C CG  . TYR A 1 111 ? 163.949 145.270 170.382 1.00 259.67 ? 420 TYR B CG  1 
ATOM 440  C CD1 . TYR A 1 111 ? 164.424 145.724 171.603 1.00 259.67 ? 420 TYR B CD1 1 
ATOM 441  C CD2 . TYR A 1 111 ? 164.406 144.045 169.916 1.00 259.67 ? 420 TYR B CD2 1 
ATOM 442  C CE1 . TYR A 1 111 ? 165.308 144.973 172.350 1.00 259.67 ? 420 TYR B CE1 1 
ATOM 443  C CE2 . TYR A 1 111 ? 165.290 143.284 170.655 1.00 259.67 ? 420 TYR B CE2 1 
ATOM 444  C CZ  . TYR A 1 111 ? 165.739 143.753 171.871 1.00 259.67 ? 420 TYR B CZ  1 
ATOM 445  N N   . ARG A 1 112 ? 160.816 148.504 170.264 1.00 230.55 ? 421 ARG B N   1 
ATOM 446  C CA  . ARG A 1 112 ? 160.389 149.816 169.790 1.00 230.55 ? 421 ARG B CA  1 
ATOM 447  C C   . ARG A 1 112 ? 159.025 149.780 169.116 1.00 230.55 ? 421 ARG B C   1 
ATOM 448  O O   . ARG A 1 112 ? 158.720 150.637 168.284 1.00 230.55 ? 421 ARG B O   1 
ATOM 449  C CB  . ARG A 1 112 ? 161.429 150.425 168.841 1.00 230.55 ? 421 ARG B CB  1 
ATOM 450  C CG  . ARG A 1 112 ? 162.858 150.372 169.367 1.00 230.55 ? 421 ARG B CG  1 
ATOM 451  C CD  . ARG A 1 112 ? 163.873 150.551 168.248 1.00 230.55 ? 421 ARG B CD  1 
ATOM 452  N NE  . ARG A 1 112 ? 165.041 149.698 168.428 1.00 230.55 ? 421 ARG B NE  1 
ATOM 453  C CZ  . ARG A 1 112 ? 165.696 149.556 169.571 1.00 230.55 ? 421 ARG B CZ  1 
ATOM 454  N N   . CYS A 1 113 ? 158.187 148.802 169.463 1.00 259.44 ? 422 CYS B N   1 
ATOM 455  C CA  . CYS A 1 113 ? 156.811 148.762 168.972 1.00 259.44 ? 422 CYS B CA  1 
ATOM 456  C C   . CYS A 1 113 ? 155.997 149.725 169.826 1.00 259.44 ? 422 CYS B C   1 
ATOM 457  O O   . CYS A 1 113 ? 155.181 149.343 170.666 1.00 259.44 ? 422 CYS B O   1 
ATOM 458  C CB  . CYS A 1 113 ? 156.257 147.345 169.011 1.00 259.44 ? 422 CYS B CB  1 
ATOM 459  S SG  . CYS A 1 113 ? 156.789 146.319 167.626 1.00 259.44 ? 422 CYS B SG  1 
ATOM 460  N N   . LYS A 1 114 ? 156.241 151.014 169.586 1.00 271.13 ? 423 LYS B N   1 
ATOM 461  C CA  . LYS A 1 114 ? 155.688 152.059 170.434 1.00 271.13 ? 423 LYS B CA  1 
ATOM 462  C C   . LYS A 1 114 ? 154.167 152.072 170.367 1.00 271.13 ? 423 LYS B C   1 
ATOM 463  O O   . LYS A 1 114 ? 153.494 152.262 171.386 1.00 271.13 ? 423 LYS B O   1 
ATOM 464  C CB  . LYS A 1 114 ? 156.252 153.413 170.008 1.00 271.13 ? 423 LYS B CB  1 
ATOM 465  C CG  . LYS A 1 114 ? 157.773 153.497 170.050 1.00 271.13 ? 423 LYS B CG  1 
ATOM 466  C CD  . LYS A 1 114 ? 158.328 153.482 171.456 1.00 271.13 ? 423 LYS B CD  1 
ATOM 467  C CE  . LYS A 1 114 ? 159.842 153.576 171.427 1.00 271.13 ? 423 LYS B CE  1 
ATOM 468  N NZ  . LYS A 1 114 ? 160.297 154.905 170.939 1.00 271.13 ? 423 LYS B NZ  1 
ATOM 469  N N   . GLN A 1 115 ? 153.609 151.868 169.171 1.00 319.30 ? 424 GLN B N   1 
ATOM 470  C CA  . GLN A 1 115 ? 152.170 151.982 168.972 1.00 319.30 ? 424 GLN B CA  1 
ATOM 471  C C   . GLN A 1 115 ? 151.380 150.864 169.641 1.00 319.30 ? 424 GLN B C   1 
ATOM 472  O O   . GLN A 1 115 ? 150.181 151.035 169.886 1.00 319.30 ? 424 GLN B O   1 
ATOM 473  C CB  . GLN A 1 115 ? 151.860 152.021 167.474 1.00 319.30 ? 424 GLN B CB  1 
ATOM 474  C CG  . GLN A 1 115 ? 151.723 150.657 166.823 1.00 319.30 ? 424 GLN B CG  1 
ATOM 475  C CD  . GLN A 1 115 ? 153.065 150.062 166.432 1.00 319.30 ? 424 GLN B CD  1 
ATOM 476  O OE1 . GLN A 1 115 ? 154.106 150.425 166.983 1.00 319.30 ? 424 GLN B OE1 1 
ATOM 477  N NE2 . GLN A 1 115 ? 153.047 149.148 165.468 1.00 319.30 ? 424 GLN B NE2 1 
ATOM 478  N N   . LEU A 1 116 ? 152.006 149.730 169.940 1.00 310.44 ? 425 LEU B N   1 
ATOM 479  C CA  . LEU A 1 116 ? 151.299 148.673 170.645 1.00 310.44 ? 425 LEU B CA  1 
ATOM 480  C C   . LEU A 1 116 ? 151.105 149.050 172.109 1.00 310.44 ? 425 LEU B C   1 
ATOM 481  O O   . LEU A 1 116 ? 151.912 149.770 172.702 1.00 310.44 ? 425 LEU B O   1 
ATOM 482  C CB  . LEU A 1 116 ? 152.048 147.346 170.526 1.00 310.44 ? 425 LEU B CB  1 
ATOM 483  C CG  . LEU A 1 116 ? 151.615 146.433 169.374 1.00 310.44 ? 425 LEU B CG  1 
ATOM 484  C CD1 . LEU A 1 116 ? 150.202 145.936 169.607 1.00 310.44 ? 425 LEU B CD1 1 
ATOM 485  C CD2 . LEU A 1 116 ? 151.716 147.130 168.028 1.00 310.44 ? 425 LEU B CD2 1 
ATOM 486  N N   . SER A 1 117 ? 150.022 148.553 172.692 1.00 327.85 ? 426 SER B N   1 
ATOM 487  C CA  . SER A 1 117 ? 149.583 148.969 174.016 1.00 327.85 ? 426 SER B CA  1 
ATOM 488  C C   . SER A 1 117 ? 149.809 147.846 175.028 1.00 327.85 ? 426 SER B C   1 
ATOM 489  O O   . SER A 1 117 ? 150.333 146.777 174.702 1.00 327.85 ? 426 SER B O   1 
ATOM 490  C CB  . SER A 1 117 ? 148.114 149.392 173.975 1.00 327.85 ? 426 SER B CB  1 
ATOM 491  O OG  . SER A 1 117 ? 147.261 148.260 173.957 1.00 327.85 ? 426 SER B OG  1 
ATOM 492  N N   . ASP A 1 118 ? 149.403 148.106 176.274 1.00 310.53 ? 427 ASP B N   1 
ATOM 493  C CA  . ASP A 1 118 ? 149.519 147.104 177.328 1.00 310.53 ? 427 ASP B CA  1 
ATOM 494  C C   . ASP A 1 118 ? 148.579 145.928 177.096 1.00 310.53 ? 427 ASP B C   1 
ATOM 495  O O   . ASP A 1 118 ? 148.825 144.829 177.606 1.00 310.53 ? 427 ASP B O   1 
ATOM 496  C CB  . ASP A 1 118 ? 149.247 147.742 178.690 1.00 310.53 ? 427 ASP B CB  1 
ATOM 497  C CG  . ASP A 1 118 ? 147.904 148.453 178.747 1.00 310.53 ? 427 ASP B CG  1 
ATOM 498  O OD1 . ASP A 1 118 ? 147.161 148.419 177.744 1.00 310.53 ? 427 ASP B OD1 1 
ATOM 499  O OD2 . ASP A 1 118 ? 147.587 149.045 179.799 1.00 310.53 ? 427 ASP B OD2 1 
ATOM 500  N N   . THR A 1 119 ? 147.497 146.136 176.344 1.00 329.37 ? 428 THR B N   1 
ATOM 501  C CA  . THR A 1 119 ? 146.607 145.026 176.025 1.00 329.37 ? 428 THR B CA  1 
ATOM 502  C C   . THR A 1 119 ? 147.332 143.952 175.228 1.00 329.37 ? 428 THR B C   1 
ATOM 503  O O   . THR A 1 119 ? 146.977 142.771 175.312 1.00 329.37 ? 428 THR B O   1 
ATOM 504  C CB  . THR A 1 119 ? 145.385 145.529 175.261 1.00 329.37 ? 428 THR B CB  1 
ATOM 505  O OG1 . THR A 1 119 ? 145.814 146.268 174.110 1.00 329.37 ? 428 THR B OG1 1 
ATOM 506  C CG2 . THR A 1 119 ? 144.537 146.427 176.149 1.00 329.37 ? 428 THR B CG2 1 
ATOM 507  N N   . SER A 1 120 ? 148.359 144.337 174.468 1.00 338.93 ? 429 SER B N   1 
ATOM 508  C CA  . SER A 1 120 ? 149.182 143.351 173.775 1.00 338.93 ? 429 SER B CA  1 
ATOM 509  C C   . SER A 1 120 ? 149.854 142.410 174.766 1.00 338.93 ? 429 SER B C   1 
ATOM 510  O O   . SER A 1 120 ? 149.793 141.182 174.614 1.00 338.93 ? 429 SER B O   1 
ATOM 511  C CB  . SER A 1 120 ? 150.230 144.055 172.912 1.00 338.93 ? 429 SER B CB  1 
ATOM 512  O OG  . SER A 1 120 ? 151.105 143.119 172.306 1.00 338.93 ? 429 SER B OG  1 
ATOM 513  N N   . ILE A 1 121 ? 150.496 142.968 175.797 1.00 312.88 ? 430 ILE B N   1 
ATOM 514  C CA  . ILE A 1 121 ? 151.167 142.117 176.772 1.00 312.88 ? 430 ILE B CA  1 
ATOM 515  C C   . ILE A 1 121 ? 150.138 141.319 177.564 1.00 312.88 ? 430 ILE B C   1 
ATOM 516  O O   . ILE A 1 121 ? 150.372 140.149 177.892 1.00 312.88 ? 430 ILE B O   1 
ATOM 517  C CB  . ILE A 1 121 ? 152.098 142.950 177.680 1.00 312.88 ? 430 ILE B CB  1 
ATOM 518  C CG1 . ILE A 1 121 ? 153.145 142.050 178.328 1.00 312.88 ? 430 ILE B CG1 1 
ATOM 519  C CG2 . ILE A 1 121 ? 151.340 143.666 178.778 1.00 312.88 ? 430 ILE B CG2 1 
ATOM 520  C CD1 . ILE A 1 121 ? 154.127 141.472 177.333 1.00 312.88 ? 430 ILE B CD1 1 
ATOM 521  N N   . ILE A 1 122 ? 148.970 141.913 177.835 1.00 302.05 ? 431 ILE B N   1 
ATOM 522  C CA  . ILE A 1 122 ? 147.910 141.203 178.550 1.00 302.05 ? 431 ILE B CA  1 
ATOM 523  C C   . ILE A 1 122 ? 147.480 139.969 177.770 1.00 302.05 ? 431 ILE B C   1 
ATOM 524  O O   . ILE A 1 122 ? 147.410 138.858 178.310 1.00 302.05 ? 431 ILE B O   1 
ATOM 525  C CB  . ILE A 1 122 ? 146.715 142.140 178.805 1.00 302.05 ? 431 ILE B CB  1 
ATOM 526  C CG1 . ILE A 1 122 ? 147.100 143.261 179.773 1.00 302.05 ? 431 ILE B CG1 1 
ATOM 527  C CG2 . ILE A 1 122 ? 145.518 141.354 179.330 1.00 302.05 ? 431 ILE B CG2 1 
ATOM 528  C CD1 . ILE A 1 122 ? 146.065 144.364 179.866 1.00 302.05 ? 431 ILE B CD1 1 
ATOM 529  N N   . ALA A 1 123 ? 147.198 140.144 176.480 1.00 316.74 ? 432 ALA B N   1 
ATOM 530  C CA  . ALA A 1 123 ? 146.735 139.030 175.666 1.00 316.74 ? 432 ALA B CA  1 
ATOM 531  C C   . ALA A 1 123 ? 147.823 137.985 175.457 1.00 316.74 ? 432 ALA B C   1 
ATOM 532  O O   . ALA A 1 123 ? 147.536 136.783 175.511 1.00 316.74 ? 432 ALA B O   1 
ATOM 533  C CB  . ALA A 1 123 ? 146.219 139.548 174.326 1.00 316.74 ? 432 ALA B CB  1 
ATOM 534  N N   . VAL A 1 124 ? 149.071 138.407 175.230 1.00 319.64 ? 433 VAL B N   1 
ATOM 535  C CA  . VAL A 1 124 ? 150.121 137.432 174.942 1.00 319.64 ? 433 VAL B CA  1 
ATOM 536  C C   . VAL A 1 124 ? 150.563 136.680 176.192 1.00 319.64 ? 433 VAL B C   1 
ATOM 537  O O   . VAL A 1 124 ? 151.051 135.548 176.083 1.00 319.64 ? 433 VAL B O   1 
ATOM 538  C CB  . VAL A 1 124 ? 151.333 138.101 174.266 1.00 319.64 ? 433 VAL B CB  1 
ATOM 539  C CG1 . VAL A 1 124 ? 152.070 139.008 175.235 1.00 319.64 ? 433 VAL B CG1 1 
ATOM 540  C CG2 . VAL A 1 124 ? 152.275 137.055 173.673 1.00 319.64 ? 433 VAL B CG2 1 
ATOM 541  N N   . ALA A 1 125 ? 150.394 137.259 177.381 1.00 328.59 ? 434 ALA B N   1 
ATOM 542  C CA  . ALA A 1 125 ? 150.711 136.551 178.610 1.00 328.59 ? 434 ALA B CA  1 
ATOM 543  C C   . ALA A 1 125 ? 149.525 135.794 179.184 1.00 328.59 ? 434 ALA B C   1 
ATOM 544  O O   . ALA A 1 125 ? 149.724 134.909 180.025 1.00 328.59 ? 434 ALA B O   1 
ATOM 545  C CB  . ALA A 1 125 ? 151.236 137.528 179.663 1.00 328.59 ? 434 ALA B CB  1 
ATOM 546  N N   . SER A 1 126 ? 148.308 136.116 178.752 1.00 325.00 ? 435 SER B N   1 
ATOM 547  C CA  . SER A 1 126 ? 147.102 135.493 179.272 1.00 325.00 ? 435 SER B CA  1 
ATOM 548  C C   . SER A 1 126 ? 146.723 134.221 178.532 1.00 325.00 ? 435 SER B C   1 
ATOM 549  O O   . SER A 1 126 ? 145.759 133.558 178.927 1.00 325.00 ? 435 SER B O   1 
ATOM 550  C CB  . SER A 1 126 ? 145.935 136.484 179.199 1.00 325.00 ? 435 SER B CB  1 
ATOM 551  O OG  . SER A 1 126 ? 145.559 136.722 177.851 1.00 325.00 ? 435 SER B OG  1 
ATOM 552  N N   . HIS A 1 127 ? 147.456 133.856 177.481 1.00 333.14 ? 436 HIS B N   1 
ATOM 553  C CA  . HIS A 1 127 ? 146.979 132.831 176.562 1.00 333.14 ? 436 HIS B CA  1 
ATOM 554  C C   . HIS A 1 127 ? 148.012 131.734 176.323 1.00 333.14 ? 436 HIS B C   1 
ATOM 555  O O   . HIS A 1 127 ? 147.752 130.805 175.554 1.00 333.14 ? 436 HIS B O   1 
ATOM 556  C CB  . HIS A 1 127 ? 146.561 133.489 175.247 1.00 333.14 ? 436 HIS B CB  1 
ATOM 557  C CG  . HIS A 1 127 ? 145.307 134.300 175.363 1.00 333.14 ? 436 HIS B CG  1 
ATOM 558  N ND1 . HIS A 1 127 ? 144.887 135.169 174.379 1.00 333.14 ? 436 HIS B ND1 1 
ATOM 559  C CD2 . HIS A 1 127 ? 144.387 134.381 176.352 1.00 333.14 ? 436 HIS B CD2 1 
ATOM 560  C CE1 . HIS A 1 127 ? 143.763 135.749 174.759 1.00 333.14 ? 436 HIS B CE1 1 
ATOM 561  N NE2 . HIS A 1 127 ? 143.438 135.288 175.952 1.00 333.14 ? 436 HIS B NE2 1 
ATOM 562  N N   . CYS A 1 128 ? 149.172 131.819 176.968 1.00 321.69 ? 437 CYS B N   1 
ATOM 563  C CA  . CYS A 1 128 ? 150.161 130.747 176.928 1.00 321.69 ? 437 CYS B CA  1 
ATOM 564  C C   . CYS A 1 128 ? 150.935 130.741 178.239 1.00 321.69 ? 437 CYS B C   1 
ATOM 565  O O   . CYS A 1 128 ? 151.651 131.702 178.545 1.00 321.69 ? 437 CYS B O   1 
ATOM 566  C CB  . CYS A 1 128 ? 151.110 130.900 175.737 1.00 321.69 ? 437 CYS B CB  1 
ATOM 567  S SG  . CYS A 1 128 ? 151.955 132.496 175.599 1.00 321.69 ? 437 CYS B SG  1 
ATOM 568  N N   . PRO A 1 129 ? 150.820 129.685 179.038 1.00 319.84 ? 438 PRO B N   1 
ATOM 569  C CA  . PRO A 1 129 ? 151.502 129.671 180.338 1.00 319.84 ? 438 PRO B CA  1 
ATOM 570  C C   . PRO A 1 129 ? 152.998 129.490 180.175 1.00 319.84 ? 438 PRO B C   1 
ATOM 571  O O   . PRO A 1 129 ? 153.756 129.531 181.149 1.00 319.84 ? 438 PRO B O   1 
ATOM 572  C CB  . PRO A 1 129 ? 150.870 128.472 181.050 1.00 319.84 ? 438 PRO B CB  1 
ATOM 573  C CG  . PRO A 1 129 ? 150.508 127.547 179.935 1.00 319.84 ? 438 PRO B CG  1 
ATOM 574  C CD  . PRO A 1 129 ? 150.108 128.423 178.773 1.00 319.84 ? 438 PRO B CD  1 
ATOM 575  N N   . LEU A 1 130 ? 153.430 129.295 178.934 1.00 287.07 ? 439 LEU B N   1 
ATOM 576  C CA  . LEU A 1 130 ? 154.814 128.971 178.635 1.00 287.07 ? 439 LEU B CA  1 
ATOM 577  C C   . LEU A 1 130 ? 155.472 130.167 177.964 1.00 287.07 ? 439 LEU B C   1 
ATOM 578  O O   . LEU A 1 130 ? 154.901 130.758 177.041 1.00 287.07 ? 439 LEU B O   1 
ATOM 579  C CB  . LEU A 1 130 ? 154.904 127.727 177.750 1.00 287.07 ? 439 LEU B CB  1 
ATOM 580  C CG  . LEU A 1 130 ? 156.305 127.250 177.393 1.00 287.07 ? 439 LEU B CG  1 
ATOM 581  C CD1 . LEU A 1 130 ? 157.063 126.896 178.657 1.00 287.07 ? 439 LEU B CD1 1 
ATOM 582  C CD2 . LEU A 1 130 ? 156.214 126.045 176.475 1.00 287.07 ? 439 LEU B CD2 1 
ATOM 583  N N   . LEU A 1 131 ? 156.657 130.530 178.448 1.00 243.79 ? 440 LEU B N   1 
ATOM 584  C CA  . LEU A 1 131 ? 157.419 131.642 177.903 1.00 243.79 ? 440 LEU B CA  1 
ATOM 585  C C   . LEU A 1 131 ? 158.867 131.514 178.348 1.00 243.79 ? 440 LEU B C   1 
ATOM 586  O O   . LEU A 1 131 ? 159.158 131.150 179.489 1.00 243.79 ? 440 LEU B O   1 
ATOM 587  C CB  . LEU A 1 131 ? 156.840 132.991 178.338 1.00 243.79 ? 440 LEU B CB  1 
ATOM 588  C CG  . LEU A 1 131 ? 157.526 134.214 177.736 1.00 243.79 ? 440 LEU B CG  1 
ATOM 589  C CD1 . LEU A 1 131 ? 157.439 134.193 176.221 1.00 243.79 ? 440 LEU B CD1 1 
ATOM 590  C CD2 . LEU A 1 131 ? 156.908 135.484 178.292 1.00 243.79 ? 440 LEU B CD2 1 
ATOM 591  N N   . GLN A 1 132 ? 159.776 131.820 177.427 1.00 213.76 ? 441 GLN B N   1 
ATOM 592  C CA  . GLN A 1 132 ? 161.203 131.695 177.683 1.00 213.76 ? 441 GLN B CA  1 
ATOM 593  C C   . GLN A 1 132 ? 161.987 132.982 177.465 1.00 213.76 ? 441 GLN B C   1 
ATOM 594  O O   . GLN A 1 132 ? 163.075 133.118 178.039 1.00 213.76 ? 441 GLN B O   1 
ATOM 595  C CB  . GLN A 1 132 ? 161.800 130.588 176.800 1.00 213.76 ? 441 GLN B CB  1 
ATOM 596  C CG  . GLN A 1 132 ? 163.038 129.929 177.363 1.00 213.76 ? 441 GLN B CG  1 
ATOM 597  C CD  . GLN A 1 132 ? 163.793 129.130 176.323 1.00 213.76 ? 441 GLN B CD  1 
ATOM 598  O OE1 . GLN A 1 132 ? 163.411 129.094 175.155 1.00 213.76 ? 441 GLN B OE1 1 
ATOM 599  N NE2 . GLN A 1 132 ? 164.869 128.478 176.744 1.00 213.76 ? 441 GLN B NE2 1 
ATOM 600  N N   . LYS A 1 133 ? 161.476 133.928 176.678 1.00 216.81 ? 442 LYS B N   1 
ATOM 601  C CA  . LYS A 1 133 ? 162.152 135.197 176.436 1.00 216.81 ? 442 LYS B CA  1 
ATOM 602  C C   . LYS A 1 133 ? 161.097 136.254 176.149 1.00 216.81 ? 442 LYS B C   1 
ATOM 603  O O   . LYS A 1 133 ? 160.237 136.051 175.287 1.00 216.81 ? 442 LYS B O   1 
ATOM 604  C CB  . LYS A 1 133 ? 163.126 135.093 175.262 1.00 216.81 ? 442 LYS B CB  1 
ATOM 605  C CG  . LYS A 1 133 ? 163.517 136.441 174.694 1.00 216.81 ? 442 LYS B CG  1 
ATOM 606  C CD  . LYS A 1 133 ? 164.279 136.299 173.392 1.00 216.81 ? 442 LYS B CD  1 
ATOM 607  C CE  . LYS A 1 133 ? 164.790 137.649 172.915 1.00 216.81 ? 442 LYS B CE  1 
ATOM 608  N NZ  . LYS A 1 133 ? 164.596 137.836 171.452 1.00 216.81 ? 442 LYS B NZ  1 
ATOM 609  N N   . VAL A 1 134 ? 161.155 137.369 176.877 1.00 187.57 ? 443 VAL B N   1 
ATOM 610  C CA  . VAL A 1 134 ? 160.137 138.408 176.767 1.00 187.57 ? 443 VAL B CA  1 
ATOM 611  C C   . VAL A 1 134 ? 160.781 139.763 176.479 1.00 187.57 ? 443 VAL B C   1 
ATOM 612  O O   . VAL A 1 134 ? 160.273 140.810 176.897 1.00 187.57 ? 443 VAL B O   1 
ATOM 613  C CB  . VAL A 1 134 ? 159.264 138.435 178.038 1.00 187.57 ? 443 VAL B CB  1 
ATOM 614  C CG1 . VAL A 1 134 ? 160.027 139.021 179.228 1.00 187.57 ? 443 VAL B CG1 1 
ATOM 615  C CG2 . VAL A 1 134 ? 157.930 139.148 177.786 1.00 187.57 ? 443 VAL B CG2 1 
ATOM 616  N N   . HIS A 1 135 ? 161.882 139.769 175.730 1.00 191.10 ? 444 HIS B N   1 
ATOM 617  C CA  . HIS A 1 135 ? 162.623 141.014 175.566 1.00 191.10 ? 444 HIS B CA  1 
ATOM 618  C C   . HIS A 1 135 ? 161.839 142.025 174.743 1.00 191.10 ? 444 HIS B C   1 
ATOM 619  O O   . HIS A 1 135 ? 162.112 142.205 173.554 1.00 191.10 ? 444 HIS B O   1 
ATOM 620  C CB  . HIS A 1 135 ? 163.968 140.779 174.873 1.00 191.10 ? 444 HIS B CB  1 
ATOM 621  C CG  . HIS A 1 135 ? 164.956 140.009 175.687 1.00 191.10 ? 444 HIS B CG  1 
ATOM 622  N ND1 . HIS A 1 135 ? 166.147 139.553 175.166 1.00 191.10 ? 444 HIS B ND1 1 
ATOM 623  C CD2 . HIS A 1 135 ? 164.930 139.602 176.977 1.00 191.10 ? 444 HIS B CD2 1 
ATOM 624  C CE1 . HIS A 1 135 ? 166.818 138.909 176.102 1.00 191.10 ? 444 HIS B CE1 1 
ATOM 625  N NE2 . HIS A 1 135 ? 166.101 138.924 177.211 1.00 191.10 ? 444 HIS B NE2 1 
ATOM 626  N N   . VAL A 1 136 ? 160.888 142.709 175.362 1.00 197.60 ? 445 VAL B N   1 
ATOM 627  C CA  . VAL A 1 136 ? 160.217 143.812 174.696 1.00 197.60 ? 445 VAL B CA  1 
ATOM 628  C C   . VAL A 1 136 ? 161.153 145.012 174.703 1.00 197.60 ? 445 VAL B C   1 
ATOM 629  O O   . VAL A 1 136 ? 162.116 145.079 175.471 1.00 197.60 ? 445 VAL B O   1 
ATOM 630  C CB  . VAL A 1 136 ? 158.863 144.152 175.347 1.00 197.60 ? 445 VAL B CB  1 
ATOM 631  C CG1 . VAL A 1 136 ? 157.916 142.969 175.250 1.00 197.60 ? 445 VAL B CG1 1 
ATOM 632  C CG2 . VAL A 1 136 ? 159.065 144.558 176.790 1.00 197.60 ? 445 VAL B CG2 1 
ATOM 633  N N   . GLY A 1 137 ? 160.867 145.976 173.835 1.00 214.57 ? 446 GLY B N   1 
ATOM 634  C CA  . GLY A 1 137 ? 161.788 147.072 173.621 1.00 214.57 ? 446 GLY B CA  1 
ATOM 635  C C   . GLY A 1 137 ? 161.381 148.383 174.256 1.00 214.57 ? 446 GLY B C   1 
ATOM 636  O O   . GLY A 1 137 ? 160.750 148.408 175.316 1.00 214.57 ? 446 GLY B O   1 
ATOM 637  N N   . ASN A 1 138 ? 161.719 149.485 173.593 1.00 208.25 ? 447 ASN B N   1 
ATOM 638  C CA  . ASN A 1 138 ? 161.547 150.816 174.149 1.00 208.25 ? 447 ASN B CA  1 
ATOM 639  C C   . ASN A 1 138 ? 160.104 151.274 174.128 1.00 208.25 ? 447 ASN B C   1 
ATOM 640  O O   . ASN A 1 138 ? 159.848 152.463 174.348 1.00 208.25 ? 447 ASN B O   1 
ATOM 641  C CB  . ASN A 1 138 ? 162.410 151.816 173.381 1.00 208.25 ? 447 ASN B CB  1 
ATOM 642  C CG  . ASN A 1 138 ? 163.886 151.503 173.476 1.00 208.25 ? 447 ASN B CG  1 
ATOM 643  O OD1 . ASN A 1 138 ? 164.378 151.098 174.525 1.00 208.25 ? 447 ASN B OD1 1 
ATOM 644  N ND2 . ASN A 1 138 ? 164.602 151.685 172.374 1.00 208.25 ? 447 ASN B ND2 1 
ATOM 645  N N   . GLN A 1 139 ? 159.166 150.365 173.874 1.00 229.85 ? 448 GLN B N   1 
ATOM 646  C CA  . GLN A 1 139 ? 157.771 150.744 173.693 1.00 229.85 ? 448 GLN B CA  1 
ATOM 647  C C   . GLN A 1 139 ? 157.220 151.415 174.944 1.00 229.85 ? 448 GLN B C   1 
ATOM 648  O O   . GLN A 1 139 ? 157.313 150.876 176.052 1.00 229.85 ? 448 GLN B O   1 
ATOM 649  C CB  . GLN A 1 139 ? 156.940 149.520 173.305 1.00 229.85 ? 448 GLN B CB  1 
ATOM 650  C CG  . GLN A 1 139 ? 156.861 148.413 174.343 1.00 229.85 ? 448 GLN B CG  1 
ATOM 651  C CD  . GLN A 1 139 ? 156.072 147.219 173.845 1.00 229.85 ? 448 GLN B CD  1 
ATOM 652  O OE1 . GLN A 1 139 ? 155.528 147.237 172.740 1.00 229.85 ? 448 GLN B OE1 1 
ATOM 653  N NE2 . GLN A 1 139 ? 156.019 146.165 174.650 1.00 229.85 ? 448 GLN B NE2 1 
ATOM 654  N N   . ASP A 1 140 ? 156.666 152.609 174.758 1.00 261.77 ? 449 ASP B N   1 
ATOM 655  C CA  . ASP A 1 140 ? 156.181 153.424 175.861 1.00 261.77 ? 449 ASP B CA  1 
ATOM 656  C C   . ASP A 1 140 ? 154.728 153.067 176.161 1.00 261.77 ? 449 ASP B C   1 
ATOM 657  O O   . ASP A 1 140 ? 154.204 152.053 175.693 1.00 261.77 ? 449 ASP B O   1 
ATOM 658  C CB  . ASP A 1 140 ? 156.351 154.905 175.533 1.00 261.77 ? 449 ASP B CB  1 
ATOM 659  C CG  . ASP A 1 140 ? 157.806 155.315 175.449 1.00 261.77 ? 449 ASP B CG  1 
ATOM 660  O OD1 . ASP A 1 140 ? 158.638 154.711 176.157 1.00 261.77 ? 449 ASP B OD1 1 
ATOM 661  O OD2 . ASP A 1 140 ? 158.117 156.242 174.673 1.00 261.77 ? 449 ASP B OD2 1 
ATOM 662  N N   . LYS A 1 141 ? 154.076 153.907 176.971 1.00 300.38 ? 450 LYS B N   1 
ATOM 663  C CA  . LYS A 1 141 ? 152.684 153.768 177.396 1.00 300.38 ? 450 LYS B CA  1 
ATOM 664  C C   . LYS A 1 141 ? 152.341 152.336 177.796 1.00 300.38 ? 450 LYS B C   1 
ATOM 665  O O   . LYS A 1 141 ? 151.211 151.875 177.605 1.00 300.38 ? 450 LYS B O   1 
ATOM 666  C CB  . LYS A 1 141 ? 151.730 154.293 176.311 1.00 300.38 ? 450 LYS B CB  1 
ATOM 667  C CG  . LYS A 1 141 ? 151.619 153.477 175.029 1.00 300.38 ? 450 LYS B CG  1 
ATOM 668  C CD  . LYS A 1 141 ? 150.642 154.126 174.059 1.00 300.38 ? 450 LYS B CD  1 
ATOM 669  C CE  . LYS A 1 141 ? 151.037 153.875 172.614 1.00 300.38 ? 450 LYS B CE  1 
ATOM 670  N NZ  . LYS A 1 141 ? 151.453 152.463 172.397 1.00 300.38 ? 450 LYS B NZ  1 
ATOM 671  N N   . LEU A 1 142 ? 153.315 151.635 178.372 1.00 292.13 ? 451 LEU B N   1 
ATOM 672  C CA  . LEU A 1 142 ? 153.132 150.281 178.886 1.00 292.13 ? 451 LEU B CA  1 
ATOM 673  C C   . LEU A 1 142 ? 153.057 150.365 180.407 1.00 292.13 ? 451 LEU B C   1 
ATOM 674  O O   . LEU A 1 142 ? 154.085 150.420 181.087 1.00 292.13 ? 451 LEU B O   1 
ATOM 675  C CB  . LEU A 1 142 ? 154.266 149.372 178.421 1.00 292.13 ? 451 LEU B CB  1 
ATOM 676  C CG  . LEU A 1 142 ? 154.087 147.866 178.610 1.00 292.13 ? 451 LEU B CG  1 
ATOM 677  C CD1 . LEU A 1 142 ? 154.782 147.129 177.489 1.00 292.13 ? 451 LEU B CD1 1 
ATOM 678  C CD2 . LEU A 1 142 ? 154.632 147.409 179.957 1.00 292.13 ? 451 LEU B CD2 1 
ATOM 679  N N   . THR A 1 143 ? 151.838 150.371 180.937 1.00 322.29 ? 452 THR B N   1 
ATOM 680  C CA  . THR A 1 143 ? 151.634 150.466 182.373 1.00 322.29 ? 452 THR B CA  1 
ATOM 681  C C   . THR A 1 143 ? 152.112 149.195 183.075 1.00 322.29 ? 452 THR B C   1 
ATOM 682  O O   . THR A 1 143 ? 152.658 148.273 182.463 1.00 322.29 ? 452 THR B O   1 
ATOM 683  C CB  . THR A 1 143 ? 150.163 150.715 182.695 1.00 322.29 ? 452 THR B CB  1 
ATOM 684  O OG1 . THR A 1 143 ? 150.027 151.044 184.083 1.00 322.29 ? 452 THR B OG1 1 
ATOM 685  C CG2 . THR A 1 143 ? 149.340 149.474 182.395 1.00 322.29 ? 452 THR B CG2 1 
ATOM 686  N N   . ASP A 1 144 ? 151.915 149.166 184.391 1.00 296.64 ? 453 ASP B N   1 
ATOM 687  C CA  . ASP A 1 144 ? 152.349 148.031 185.191 1.00 296.64 ? 453 ASP B CA  1 
ATOM 688  C C   . ASP A 1 144 ? 151.234 147.025 185.460 1.00 296.64 ? 453 ASP B C   1 
ATOM 689  O O   . ASP A 1 144 ? 151.523 145.924 185.943 1.00 296.64 ? 453 ASP B O   1 
ATOM 690  C CB  . ASP A 1 144 ? 152.946 148.544 186.504 1.00 296.64 ? 453 ASP B CB  1 
ATOM 691  C CG  . ASP A 1 144 ? 154.027 147.636 187.048 1.00 296.64 ? 453 ASP B CG  1 
ATOM 692  O OD1 . ASP A 1 144 ? 154.194 146.518 186.519 1.00 296.64 ? 453 ASP B OD1 1 
ATOM 693  O OD2 . ASP A 1 144 ? 154.751 148.067 187.966 1.00 296.64 ? 453 ASP B OD2 1 
ATOM 694  N N   . GLU A 1 145 ? 149.977 147.364 185.156 1.00 327.03 ? 454 GLU B N   1 
ATOM 695  C CA  . GLU A 1 145 ? 148.880 146.422 185.375 1.00 327.03 ? 454 GLU B CA  1 
ATOM 696  C C   . GLU A 1 145 ? 149.012 145.189 184.487 1.00 327.03 ? 454 GLU B C   1 
ATOM 697  O O   . GLU A 1 145 ? 148.714 144.071 184.921 1.00 327.03 ? 454 GLU B O   1 
ATOM 698  C CB  . GLU A 1 145 ? 147.530 147.105 185.143 1.00 327.03 ? 454 GLU B CB  1 
ATOM 699  C CG  . GLU A 1 145 ? 147.023 147.925 186.322 1.00 327.03 ? 454 GLU B CG  1 
ATOM 700  C CD  . GLU A 1 145 ? 147.618 149.316 186.377 1.00 327.03 ? 454 GLU B CD  1 
ATOM 701  O OE1 . GLU A 1 145 ? 148.388 149.673 185.463 1.00 327.03 ? 454 GLU B OE1 1 
ATOM 702  O OE2 . GLU A 1 145 ? 147.309 150.055 187.337 1.00 327.03 ? 454 GLU B OE2 1 
ATOM 703  N N   . GLY A 1 146 ? 149.432 145.373 183.235 1.00 314.34 ? 455 GLY B N   1 
ATOM 704  C CA  . GLY A 1 146 ? 149.623 144.226 182.363 1.00 314.34 ? 455 GLY B CA  1 
ATOM 705  C C   . GLY A 1 146 ? 150.756 143.328 182.818 1.00 314.34 ? 455 GLY B C   1 
ATOM 706  O O   . GLY A 1 146 ? 150.671 142.100 182.715 1.00 314.34 ? 455 GLY B O   1 
ATOM 707  N N   . LEU A 1 147 ? 151.835 143.925 183.326 1.00 285.33 ? 456 LEU B N   1 
ATOM 708  C CA  . LEU A 1 147 ? 152.950 143.130 183.823 1.00 285.33 ? 456 LEU B CA  1 
ATOM 709  C C   . LEU A 1 147 ? 152.537 142.335 185.054 1.00 285.33 ? 456 LEU B C   1 
ATOM 710  O O   . LEU A 1 147 ? 153.055 141.234 185.291 1.00 285.33 ? 456 LEU B O   1 
ATOM 711  C CB  . LEU A 1 147 ? 154.137 144.050 184.116 1.00 285.33 ? 456 LEU B CB  1 
ATOM 712  C CG  . LEU A 1 147 ? 155.547 143.467 184.188 1.00 285.33 ? 456 LEU B CG  1 
ATOM 713  C CD1 . LEU A 1 147 ? 156.549 144.542 183.824 1.00 285.33 ? 456 LEU B CD1 1 
ATOM 714  C CD2 . LEU A 1 147 ? 155.853 142.933 185.551 1.00 285.33 ? 456 LEU B CD2 1 
ATOM 715  N N   . LYS A 1 148 ? 151.584 142.866 185.826 1.00 310.58 ? 457 LYS B N   1 
ATOM 716  C CA  . LYS A 1 148 ? 150.988 142.113 186.924 1.00 310.58 ? 457 LYS B CA  1 
ATOM 717  C C   . LYS A 1 148 ? 150.412 140.796 186.423 1.00 310.58 ? 457 LYS B C   1 
ATOM 718  O O   . LYS A 1 148 ? 150.695 139.725 186.973 1.00 310.58 ? 457 LYS B O   1 
ATOM 719  C CB  . LYS A 1 148 ? 149.886 142.946 187.584 1.00 310.58 ? 457 LYS B CB  1 
ATOM 720  C CG  . LYS A 1 148 ? 150.342 143.940 188.637 1.00 310.58 ? 457 LYS B CG  1 
ATOM 721  C CD  . LYS A 1 148 ? 149.225 144.203 189.639 1.00 310.58 ? 457 LYS B CD  1 
ATOM 722  C CE  . LYS A 1 148 ? 149.518 145.423 190.497 1.00 310.58 ? 457 LYS B CE  1 
ATOM 723  N NZ  . LYS A 1 148 ? 150.033 146.560 189.687 1.00 310.58 ? 457 LYS B NZ  1 
ATOM 724  N N   . GLN A 1 149 ? 149.605 140.860 185.363 1.00 329.95 ? 458 GLN B N   1 
ATOM 725  C CA  . GLN A 1 149 ? 148.996 139.652 184.820 1.00 329.95 ? 458 GLN B CA  1 
ATOM 726  C C   . GLN A 1 149 ? 150.045 138.741 184.194 1.00 329.95 ? 458 GLN B C   1 
ATOM 727  O O   . GLN A 1 149 ? 149.933 137.511 184.272 1.00 329.95 ? 458 GLN B O   1 
ATOM 728  C CB  . GLN A 1 149 ? 147.921 140.030 183.802 1.00 329.95 ? 458 GLN B CB  1 
ATOM 729  C CG  . GLN A 1 149 ? 146.931 141.069 184.318 1.00 329.95 ? 458 GLN B CG  1 
ATOM 730  C CD  . GLN A 1 149 ? 145.501 140.777 183.904 1.00 329.95 ? 458 GLN B CD  1 
ATOM 731  O OE1 . GLN A 1 149 ? 145.250 139.916 183.062 1.00 329.95 ? 458 GLN B OE1 1 
ATOM 732  N NE2 . GLN A 1 149 ? 144.556 141.497 184.496 1.00 329.95 ? 458 GLN B NE2 1 
ATOM 733  N N   . LEU A 1 150 ? 151.071 139.325 183.564 1.00 326.22 ? 459 LEU B N   1 
ATOM 734  C CA  . LEU A 1 150 ? 152.132 138.501 182.989 1.00 326.22 ? 459 LEU B CA  1 
ATOM 735  C C   . LEU A 1 150 ? 152.816 137.674 184.068 1.00 326.22 ? 459 LEU B C   1 
ATOM 736  O O   . LEU A 1 150 ? 153.088 136.485 183.873 1.00 326.22 ? 459 LEU B O   1 
ATOM 737  C CB  . LEU A 1 150 ? 153.163 139.364 182.255 1.00 326.22 ? 459 LEU B CB  1 
ATOM 738  C CG  . LEU A 1 150 ? 154.180 138.572 181.411 1.00 326.22 ? 459 LEU B CG  1 
ATOM 739  C CD1 . LEU A 1 150 ? 154.402 139.207 180.050 1.00 326.22 ? 459 LEU B CD1 1 
ATOM 740  C CD2 . LEU A 1 150 ? 155.507 138.380 182.113 1.00 326.22 ? 459 LEU B CD2 1 
ATOM 741  N N   . GLY A 1 151 ? 153.099 138.289 185.215 1.00 314.84 ? 460 GLY B N   1 
ATOM 742  C CA  . GLY A 1 151 ? 153.602 137.518 186.334 1.00 314.84 ? 460 GLY B CA  1 
ATOM 743  C C   . GLY A 1 151 ? 152.611 136.526 186.902 1.00 314.84 ? 460 GLY B C   1 
ATOM 744  O O   . GLY A 1 151 ? 153.012 135.431 187.308 1.00 314.84 ? 460 GLY B O   1 
ATOM 745  N N   . SER A 1 152 ? 151.324 136.881 186.926 1.00 320.91 ? 461 SER B N   1 
ATOM 746  C CA  . SER A 1 152 ? 150.326 136.031 187.570 1.00 320.91 ? 461 SER B CA  1 
ATOM 747  C C   . SER A 1 152 ? 150.061 134.755 186.782 1.00 320.91 ? 461 SER B C   1 
ATOM 748  O O   . SER A 1 152 ? 149.887 133.683 187.374 1.00 320.91 ? 461 SER B O   1 
ATOM 749  C CB  . SER A 1 152 ? 149.023 136.808 187.763 1.00 320.91 ? 461 SER B CB  1 
ATOM 750  O OG  . SER A 1 152 ? 148.233 136.778 186.586 1.00 320.91 ? 461 SER B OG  1 
ATOM 751  N N   . LYS A 1 153 ? 150.022 134.840 185.453 1.00 325.29 ? 462 LYS B N   1 
ATOM 752  C CA  . LYS A 1 153 ? 149.605 133.685 184.664 1.00 325.29 ? 462 LYS B CA  1 
ATOM 753  C C   . LYS A 1 153 ? 150.757 132.711 184.436 1.00 325.29 ? 462 LYS B C   1 
ATOM 754  O O   . LYS A 1 153 ? 150.695 131.551 184.859 1.00 325.29 ? 462 LYS B O   1 
ATOM 755  C CB  . LYS A 1 153 ? 149.009 134.150 183.331 1.00 325.29 ? 462 LYS B CB  1 
ATOM 756  C CG  . LYS A 1 153 ? 147.835 135.109 183.484 1.00 325.29 ? 462 LYS B CG  1 
ATOM 757  C CD  . LYS A 1 153 ? 146.852 134.631 184.547 1.00 325.29 ? 462 LYS B CD  1 
ATOM 758  C CE  . LYS A 1 153 ? 145.910 133.567 184.012 1.00 325.29 ? 462 LYS B CE  1 
ATOM 759  N NZ  . LYS A 1 153 ? 144.657 133.484 184.816 1.00 325.29 ? 462 LYS B NZ  1 
ATOM 760  N N   . CYS A 1 154 ? 151.821 133.163 183.770 1.00 318.85 ? 463 CYS B N   1 
ATOM 761  C CA  . CYS A 1 154 ? 152.948 132.294 183.422 1.00 318.85 ? 463 CYS B CA  1 
ATOM 762  C C   . CYS A 1 154 ? 154.052 132.485 184.454 1.00 318.85 ? 463 CYS B C   1 
ATOM 763  O O   . CYS A 1 154 ? 154.873 133.398 184.361 1.00 318.85 ? 463 CYS B O   1 
ATOM 764  C CB  . CYS A 1 154 ? 153.439 132.589 182.010 1.00 318.85 ? 463 CYS B CB  1 
ATOM 765  S SG  . CYS A 1 154 ? 153.621 134.340 181.619 1.00 318.85 ? 463 CYS B SG  1 
ATOM 766  N N   . ARG A 1 155 ? 154.067 131.611 185.456 1.00 278.91 ? 464 ARG B N   1 
ATOM 767  C CA  . ARG A 1 155 ? 155.078 131.663 186.512 1.00 278.91 ? 464 ARG B CA  1 
ATOM 768  C C   . ARG A 1 155 ? 156.269 130.755 186.206 1.00 278.91 ? 464 ARG B C   1 
ATOM 769  O O   . ARG A 1 155 ? 156.712 129.980 187.051 1.00 278.91 ? 464 ARG B O   1 
ATOM 770  C CB  . ARG A 1 155 ? 154.438 131.288 187.843 1.00 278.91 ? 464 ARG B CB  1 
ATOM 771  C CG  . ARG A 1 155 ? 153.199 130.405 187.690 1.00 278.91 ? 464 ARG B CG  1 
ATOM 772  C CD  . ARG A 1 155 ? 152.886 129.616 188.958 1.00 278.91 ? 464 ARG B CD  1 
ATOM 773  N NE  . ARG A 1 155 ? 152.333 130.452 190.018 1.00 278.91 ? 464 ARG B NE  1 
ATOM 774  C CZ  . ARG A 1 155 ? 152.188 130.066 191.277 1.00 278.91 ? 464 ARG B CZ  1 
ATOM 775  N N   . GLU A 1 156 ? 156.811 130.856 184.993 1.00 248.38 ? 465 GLU B N   1 
ATOM 776  C CA  . GLU A 1 156 ? 157.981 130.068 184.619 1.00 248.38 ? 465 GLU B CA  1 
ATOM 777  C C   . GLU A 1 156 ? 158.955 130.814 183.720 1.00 248.38 ? 465 GLU B C   1 
ATOM 778  O O   . GLU A 1 156 ? 159.944 130.214 183.287 1.00 248.38 ? 465 GLU B O   1 
ATOM 779  C CB  . GLU A 1 156 ? 157.545 128.765 183.930 1.00 248.38 ? 465 GLU B CB  1 
ATOM 780  C CG  . GLU A 1 156 ? 156.674 128.981 182.714 1.00 248.38 ? 465 GLU B CG  1 
ATOM 781  C CD  . GLU A 1 156 ? 157.487 129.189 181.459 1.00 248.38 ? 465 GLU B CD  1 
ATOM 782  O OE1 . GLU A 1 156 ? 158.652 128.746 181.415 1.00 248.38 ? 465 GLU B OE1 1 
ATOM 783  O OE2 . GLU A 1 156 ? 156.976 129.840 180.534 1.00 248.38 ? 465 GLU B OE2 1 
ATOM 784  N N   . LEU A 1 157 ? 158.717 132.094 183.439 1.00 196.42 ? 466 LEU B N   1 
ATOM 785  C CA  . LEU A 1 157 ? 159.571 132.878 182.558 1.00 196.42 ? 466 LEU B CA  1 
ATOM 786  C C   . LEU A 1 157 ? 161.009 132.894 183.062 1.00 196.42 ? 466 LEU B C   1 
ATOM 787  O O   . LEU A 1 157 ? 161.263 132.819 184.267 1.00 196.42 ? 466 LEU B O   1 
ATOM 788  C CB  . LEU A 1 157 ? 159.017 134.299 182.464 1.00 196.42 ? 466 LEU B CB  1 
ATOM 789  C CG  . LEU A 1 157 ? 159.752 135.371 181.669 1.00 196.42 ? 466 LEU B CG  1 
ATOM 790  C CD1 . LEU A 1 157 ? 159.997 134.917 180.247 1.00 196.42 ? 466 LEU B CD1 1 
ATOM 791  C CD2 . LEU A 1 157 ? 158.923 136.642 181.698 1.00 196.42 ? 466 LEU B CD2 1 
ATOM 792  N N   . LYS A 1 158 ? 161.962 132.970 182.136 1.00 138.87 ? 467 LYS B N   1 
ATOM 793  C CA  . LYS A 1 158 ? 163.352 132.817 182.520 1.00 138.87 ? 467 LYS B CA  1 
ATOM 794  C C   . LYS A 1 158 ? 164.281 133.920 182.031 1.00 138.87 ? 467 LYS B C   1 
ATOM 795  O O   . LYS A 1 158 ? 165.464 133.897 182.386 1.00 138.87 ? 467 LYS B O   1 
ATOM 796  C CB  . LYS A 1 158 ? 163.883 131.462 182.037 1.00 138.87 ? 467 LYS B CB  1 
ATOM 797  C CG  . LYS A 1 158 ? 164.328 131.427 180.598 1.00 138.87 ? 467 LYS B CG  1 
ATOM 798  C CD  . LYS A 1 158 ? 164.976 130.091 180.300 1.00 138.87 ? 467 LYS B CD  1 
ATOM 799  C CE  . LYS A 1 158 ? 166.454 130.134 180.604 1.00 138.87 ? 467 LYS B CE  1 
ATOM 800  N NZ  . LYS A 1 158 ? 167.215 130.849 179.555 1.00 138.87 ? 467 LYS B NZ  1 
ATOM 801  N N   . ASP A 1 159 ? 163.794 134.888 181.255 1.00 146.08 ? 468 ASP B N   1 
ATOM 802  C CA  . ASP A 1 159 ? 164.673 135.916 180.696 1.00 146.08 ? 468 ASP B CA  1 
ATOM 803  C C   . ASP A 1 159 ? 163.845 137.142 180.340 1.00 146.08 ? 468 ASP B C   1 
ATOM 804  O O   . ASP A 1 159 ? 162.830 137.014 179.649 1.00 146.08 ? 468 ASP B O   1 
ATOM 805  C CB  . ASP A 1 159 ? 165.402 135.377 179.466 1.00 146.08 ? 468 ASP B CB  1 
ATOM 806  C CG  . ASP A 1 159 ? 166.759 136.004 179.274 1.00 146.08 ? 468 ASP B CG  1 
ATOM 807  O OD1 . ASP A 1 159 ? 166.841 137.248 179.272 1.00 146.08 ? 468 ASP B OD1 1 
ATOM 808  O OD2 . ASP A 1 159 ? 167.745 135.252 179.129 1.00 146.08 ? 468 ASP B OD2 1 
ATOM 809  N N   . ILE A 1 160 ? 164.267 138.324 180.804 1.00 150.93 ? 469 ILE B N   1 
ATOM 810  C CA  . ILE A 1 160 ? 163.511 139.555 180.599 1.00 150.93 ? 469 ILE B CA  1 
ATOM 811  C C   . ILE A 1 160 ? 164.434 140.694 180.169 1.00 150.93 ? 469 ILE B C   1 
ATOM 812  O O   . ILE A 1 160 ? 165.643 140.679 180.403 1.00 150.93 ? 469 ILE B O   1 
ATOM 813  C CB  . ILE A 1 160 ? 162.716 139.977 181.852 1.00 150.93 ? 469 ILE B CB  1 
ATOM 814  C CG1 . ILE A 1 160 ? 163.664 140.464 182.943 1.00 150.93 ? 469 ILE B CG1 1 
ATOM 815  C CG2 . ILE A 1 160 ? 161.828 138.853 182.348 1.00 150.93 ? 469 ILE B CG2 1 
ATOM 816  C CD1 . ILE A 1 160 ? 162.990 141.341 183.964 1.00 150.93 ? 469 ILE B CD1 1 
ATOM 817  N N   . HIS A 1 161 ? 163.818 141.699 179.540 1.00 160.27 ? 470 HIS B N   1 
ATOM 818  C CA  . HIS A 1 161 ? 164.463 142.945 179.122 1.00 160.27 ? 470 HIS B CA  1 
ATOM 819  C C   . HIS A 1 161 ? 163.386 144.010 178.997 1.00 160.27 ? 470 HIS B C   1 
ATOM 820  O O   . HIS A 1 161 ? 162.600 143.973 178.045 1.00 160.27 ? 470 HIS B O   1 
ATOM 821  C CB  . HIS A 1 161 ? 165.190 142.770 177.791 1.00 160.27 ? 470 HIS B CB  1 
ATOM 822  C CG  . HIS A 1 161 ? 165.851 144.017 177.289 1.00 160.27 ? 470 HIS B CG  1 
ATOM 823  N ND1 . HIS A 1 161 ? 165.139 145.116 176.859 1.00 160.27 ? 470 HIS B ND1 1 
ATOM 824  C CD2 . HIS A 1 161 ? 167.157 144.328 177.118 1.00 160.27 ? 470 HIS B CD2 1 
ATOM 825  C CE1 . HIS A 1 161 ? 165.977 146.057 176.464 1.00 160.27 ? 470 HIS B CE1 1 
ATOM 826  N NE2 . HIS A 1 161 ? 167.208 145.605 176.612 1.00 160.27 ? 470 HIS B NE2 1 
ATOM 827  N N   . PHE A 1 162 ? 163.342 144.953 179.939 1.00 166.02 ? 471 PHE B N   1 
ATOM 828  C CA  . PHE A 1 162 ? 162.325 146.004 179.917 1.00 166.02 ? 471 PHE B CA  1 
ATOM 829  C C   . PHE A 1 162 ? 162.968 147.380 180.005 1.00 166.02 ? 471 PHE B C   1 
ATOM 830  O O   . PHE A 1 162 ? 162.565 148.222 180.814 1.00 166.02 ? 471 PHE B O   1 
ATOM 831  C CB  . PHE A 1 162 ? 161.305 145.838 181.044 1.00 166.02 ? 471 PHE B CB  1 
ATOM 832  C CG  . PHE A 1 162 ? 160.290 144.763 180.803 1.00 166.02 ? 471 PHE B CG  1 
ATOM 833  C CD1 . PHE A 1 162 ? 158.943 145.031 180.950 1.00 166.02 ? 471 PHE B CD1 1 
ATOM 834  C CD2 . PHE A 1 162 ? 160.675 143.475 180.482 1.00 166.02 ? 471 PHE B CD2 1 
ATOM 835  C CE1 . PHE A 1 162 ? 158.003 144.049 180.739 1.00 166.02 ? 471 PHE B CE1 1 
ATOM 836  C CE2 . PHE A 1 162 ? 159.740 142.488 180.273 1.00 166.02 ? 471 PHE B CE2 1 
ATOM 837  C CZ  . PHE A 1 162 ? 158.403 142.774 180.404 1.00 166.02 ? 471 PHE B CZ  1 
ATOM 838  N N   . GLY A 1 163 ? 163.983 147.630 179.184 1.00 154.77 ? 472 GLY B N   1 
ATOM 839  C CA  . GLY A 1 163 ? 164.596 148.942 179.167 1.00 154.77 ? 472 GLY B CA  1 
ATOM 840  C C   . GLY A 1 163 ? 163.682 149.991 178.563 1.00 154.77 ? 472 GLY B C   1 
ATOM 841  O O   . GLY A 1 163 ? 162.843 149.707 177.708 1.00 154.77 ? 472 GLY B O   1 
ATOM 842  N N   . GLN A 1 164 ? 163.853 151.230 179.029 1.00 157.63 ? 473 GLN B N   1 
ATOM 843  C CA  . GLN A 1 164 ? 163.132 152.388 178.498 1.00 157.63 ? 473 GLN B CA  1 
ATOM 844  C C   . GLN A 1 164 ? 161.617 152.210 178.588 1.00 157.63 ? 473 GLN B C   1 
ATOM 845  O O   . GLN A 1 164 ? 160.875 152.578 177.676 1.00 157.63 ? 473 GLN B O   1 
ATOM 846  C CB  . GLN A 1 164 ? 163.552 152.687 177.057 1.00 157.63 ? 473 GLN B CB  1 
ATOM 847  C CG  . GLN A 1 164 ? 165.016 153.071 176.895 1.00 157.63 ? 473 GLN B CG  1 
ATOM 848  C CD  . GLN A 1 164 ? 165.323 154.462 177.405 1.00 157.63 ? 473 GLN B CD  1 
ATOM 849  O OE1 . GLN A 1 164 ? 164.512 155.378 177.270 1.00 157.63 ? 473 GLN B OE1 1 
ATOM 850  N NE2 . GLN A 1 164 ? 166.494 154.626 178.006 1.00 157.63 ? 473 GLN B NE2 1 
ATOM 851  N N   . CYS A 1 165 ? 161.155 151.635 179.692 1.00 166.27 ? 474 CYS B N   1 
ATOM 852  C CA  . CYS A 1 165 ? 159.733 151.563 180.019 1.00 166.27 ? 474 CYS B CA  1 
ATOM 853  C C   . CYS A 1 165 ? 159.589 152.104 181.436 1.00 166.27 ? 474 CYS B C   1 
ATOM 854  O O   . CYS A 1 165 ? 159.657 151.354 182.412 1.00 166.27 ? 474 CYS B O   1 
ATOM 855  C CB  . CYS A 1 165 ? 159.194 150.148 179.891 1.00 166.27 ? 474 CYS B CB  1 
ATOM 856  S SG  . CYS A 1 165 ? 159.269 149.488 178.215 1.00 166.27 ? 474 CYS B SG  1 
ATOM 857  N N   . TYR A 1 166 ? 159.387 153.413 181.541 1.00 186.48 ? 475 TYR B N   1 
ATOM 858  C CA  . TYR A 1 166 ? 159.386 154.110 182.827 1.00 186.48 ? 475 TYR B CA  1 
ATOM 859  C C   . TYR A 1 166 ? 158.014 154.069 183.489 1.00 186.48 ? 475 TYR B C   1 
ATOM 860  O O   . TYR A 1 166 ? 157.448 155.086 183.887 1.00 186.48 ? 475 TYR B O   1 
ATOM 861  C CB  . TYR A 1 166 ? 159.865 155.541 182.626 1.00 186.48 ? 475 TYR B CB  1 
ATOM 862  C CG  . TYR A 1 166 ? 160.590 155.731 181.312 1.00 186.48 ? 475 TYR B CG  1 
ATOM 863  C CD1 . TYR A 1 166 ? 161.930 155.385 181.183 1.00 186.48 ? 475 TYR B CD1 1 
ATOM 864  C CD2 . TYR A 1 166 ? 159.928 156.226 180.196 1.00 186.48 ? 475 TYR B CD2 1 
ATOM 865  C CE1 . TYR A 1 166 ? 162.593 155.548 179.985 1.00 186.48 ? 475 TYR B CE1 1 
ATOM 866  C CE2 . TYR A 1 166 ? 160.583 156.388 178.993 1.00 186.48 ? 475 TYR B CE2 1 
ATOM 867  C CZ  . TYR A 1 166 ? 161.914 156.047 178.894 1.00 186.48 ? 475 TYR B CZ  1 
ATOM 868  N N   . LYS A 1 167 ? 157.476 152.852 183.606 1.00 220.74 ? 476 LYS B N   1 
ATOM 869  C CA  . LYS A 1 167 ? 156.200 152.613 184.267 1.00 220.74 ? 476 LYS B CA  1 
ATOM 870  C C   . LYS A 1 167 ? 156.276 151.377 185.158 1.00 220.74 ? 476 LYS B C   1 
ATOM 871  O O   . LYS A 1 167 ? 155.243 150.917 185.660 1.00 220.74 ? 476 LYS B O   1 
ATOM 872  C CB  . LYS A 1 167 ? 155.074 152.427 183.242 1.00 220.74 ? 476 LYS B CB  1 
ATOM 873  C CG  . LYS A 1 167 ? 154.434 153.708 182.733 1.00 220.74 ? 476 LYS B CG  1 
ATOM 874  C CD  . LYS A 1 167 ? 155.287 154.369 181.666 1.00 220.74 ? 476 LYS B CD  1 
ATOM 875  C CE  . LYS A 1 167 ? 155.323 153.539 180.396 1.00 220.74 ? 476 LYS B CE  1 
ATOM 876  N NZ  . LYS A 1 167 ? 156.115 154.209 179.329 1.00 220.74 ? 476 LYS B NZ  1 
ATOM 877  N N   . ILE A 1 168 ? 157.475 150.831 185.359 1.00 196.90 ? 477 ILE B N   1 
ATOM 878  C CA  . ILE A 1 168 ? 157.665 149.553 186.034 1.00 196.90 ? 477 ILE B CA  1 
ATOM 879  C C   . ILE A 1 168 ? 158.553 149.748 187.253 1.00 196.90 ? 477 ILE B C   1 
ATOM 880  O O   . ILE A 1 168 ? 159.352 148.872 187.601 1.00 196.90 ? 477 ILE B O   1 
ATOM 881  C CB  . ILE A 1 168 ? 158.273 148.519 185.073 1.00 196.90 ? 477 ILE B CB  1 
ATOM 882  C CG1 . ILE A 1 168 ? 159.651 148.990 184.609 1.00 196.90 ? 477 ILE B CG1 1 
ATOM 883  C CG2 . ILE A 1 168 ? 157.361 148.315 183.877 1.00 196.90 ? 477 ILE B CG2 1 
ATOM 884  C CD1 . ILE A 1 168 ? 160.425 147.953 183.855 1.00 196.90 ? 477 ILE B CD1 1 
ATOM 885  N N   . SER A 1 169 ? 158.413 150.896 187.910 1.00 164.81 ? 478 SER B N   1 
ATOM 886  C CA  . SER A 1 169 ? 159.323 151.306 188.970 1.00 164.81 ? 478 SER B CA  1 
ATOM 887  C C   . SER A 1 169 ? 159.471 150.256 190.068 1.00 164.81 ? 478 SER B C   1 
ATOM 888  O O   . SER A 1 169 ? 160.589 149.815 190.353 1.00 164.81 ? 478 SER B O   1 
ATOM 889  C CB  . SER A 1 169 ? 158.851 152.633 189.559 1.00 164.81 ? 478 SER B CB  1 
ATOM 890  O OG  . SER A 1 169 ? 158.643 153.585 188.530 1.00 164.81 ? 478 SER B OG  1 
ATOM 891  N N   . ASP A 1 170 ? 158.366 149.844 190.683 1.00 183.02 ? 479 ASP B N   1 
ATOM 892  C CA  . ASP A 1 170 ? 158.431 148.839 191.742 1.00 183.02 ? 479 ASP B CA  1 
ATOM 893  C C   . ASP A 1 170 ? 157.454 147.687 191.569 1.00 183.02 ? 479 ASP B C   1 
ATOM 894  O O   . ASP A 1 170 ? 157.818 146.543 191.847 1.00 183.02 ? 479 ASP B O   1 
ATOM 895  C CB  . ASP A 1 170 ? 158.195 149.485 193.109 1.00 183.02 ? 479 ASP B CB  1 
ATOM 896  C CG  . ASP A 1 170 ? 159.298 150.431 193.499 1.00 183.02 ? 479 ASP B CG  1 
ATOM 897  O OD1 . ASP A 1 170 ? 160.434 150.238 193.019 1.00 183.02 ? 479 ASP B OD1 1 
ATOM 898  O OD2 . ASP A 1 170 ? 159.029 151.362 194.285 1.00 183.02 ? 479 ASP B OD2 1 
ATOM 899  N N   . GLU A 1 171 ? 156.222 147.957 191.130 1.00 219.29 ? 480 GLU B N   1 
ATOM 900  C CA  . GLU A 1 171 ? 155.196 146.917 191.143 1.00 219.29 ? 480 GLU B CA  1 
ATOM 901  C C   . GLU A 1 171 ? 155.549 145.766 190.212 1.00 219.29 ? 480 GLU B C   1 
ATOM 902  O O   . GLU A 1 171 ? 155.280 144.602 190.537 1.00 219.29 ? 480 GLU B O   1 
ATOM 903  C CB  . GLU A 1 171 ? 153.839 147.511 190.770 1.00 219.29 ? 480 GLU B CB  1 
ATOM 904  C CG  . GLU A 1 171 ? 153.368 148.587 191.723 1.00 219.29 ? 480 GLU B CG  1 
ATOM 905  C CD  . GLU A 1 171 ? 153.143 148.050 193.119 1.00 219.29 ? 480 GLU B CD  1 
ATOM 906  O OE1 . GLU A 1 171 ? 152.670 146.901 193.241 1.00 219.29 ? 480 GLU B OE1 1 
ATOM 907  O OE2 . GLU A 1 171 ? 153.459 148.765 194.092 1.00 219.29 ? 480 GLU B OE2 1 
ATOM 908  N N   . GLY A 1 172 ? 156.161 146.066 189.068 1.00 217.25 ? 481 GLY B N   1 
ATOM 909  C CA  . GLY A 1 172 ? 156.628 145.002 188.198 1.00 217.25 ? 481 GLY B CA  1 
ATOM 910  C C   . GLY A 1 172 ? 157.659 144.123 188.876 1.00 217.25 ? 481 GLY B C   1 
ATOM 911  O O   . GLY A 1 172 ? 157.650 142.902 188.717 1.00 217.25 ? 481 GLY B O   1 
ATOM 912  N N   . MET A 1 173 ? 158.546 144.732 189.659 1.00 195.52 ? 482 MET B N   1 
ATOM 913  C CA  . MET A 1 173 ? 159.542 143.960 190.393 1.00 195.52 ? 482 MET B CA  1 
ATOM 914  C C   . MET A 1 173 ? 158.901 142.998 191.383 1.00 195.52 ? 482 MET B C   1 
ATOM 915  O O   . MET A 1 173 ? 159.221 141.809 191.392 1.00 195.52 ? 482 MET B O   1 
ATOM 916  C CB  . MET A 1 173 ? 160.513 144.899 191.100 1.00 195.52 ? 482 MET B CB  1 
ATOM 917  C CG  . MET A 1 173 ? 161.436 144.196 192.058 1.00 195.52 ? 482 MET B CG  1 
ATOM 918  S SD  . MET A 1 173 ? 160.764 144.260 193.729 1.00 195.52 ? 482 MET B SD  1 
ATOM 919  C CE  . MET A 1 173 ? 160.471 146.026 193.871 1.00 195.52 ? 482 MET B CE  1 
ATOM 920  N N   . ILE A 1 174 ? 157.980 143.475 192.214 1.00 217.61 ? 483 ILE B N   1 
ATOM 921  C CA  . ILE A 1 174 ? 157.376 142.547 193.160 1.00 217.61 ? 483 ILE B CA  1 
ATOM 922  C C   . ILE A 1 174 ? 156.608 141.460 192.408 1.00 217.61 ? 483 ILE B C   1 
ATOM 923  O O   . ILE A 1 174 ? 156.724 140.268 192.736 1.00 217.61 ? 483 ILE B O   1 
ATOM 924  C CB  . ILE A 1 174 ? 156.494 143.292 194.193 1.00 217.61 ? 483 ILE B CB  1 
ATOM 925  C CG1 . ILE A 1 174 ? 156.229 142.404 195.413 1.00 217.61 ? 483 ILE B CG1 1 
ATOM 926  C CG2 . ILE A 1 174 ? 155.189 143.796 193.587 1.00 217.61 ? 483 ILE B CG2 1 
ATOM 927  C CD1 . ILE A 1 174 ? 157.455 142.135 196.250 1.00 217.61 ? 483 ILE B CD1 1 
ATOM 928  N N   . VAL A 1 175 ? 155.875 141.830 191.352 1.00 229.12 ? 484 VAL B N   1 
ATOM 929  C CA  . VAL A 1 175 ? 154.963 140.872 190.740 1.00 229.12 ? 484 VAL B CA  1 
ATOM 930  C C   . VAL A 1 175 ? 155.734 139.805 189.967 1.00 229.12 ? 484 VAL B C   1 
ATOM 931  O O   . VAL A 1 175 ? 155.483 138.610 190.143 1.00 229.12 ? 484 VAL B O   1 
ATOM 932  C CB  . VAL A 1 175 ? 153.900 141.587 189.883 1.00 229.12 ? 484 VAL B CB  1 
ATOM 933  C CG1 . VAL A 1 175 ? 154.478 142.200 188.634 1.00 229.12 ? 484 VAL B CG1 1 
ATOM 934  C CG2 . VAL A 1 175 ? 152.781 140.618 189.543 1.00 229.12 ? 484 VAL B CG2 1 
ATOM 935  N N   . ILE A 1 176 ? 156.675 140.190 189.101 1.00 216.12 ? 485 ILE B N   1 
ATOM 936  C CA  . ILE A 1 176 ? 157.620 139.162 188.689 1.00 216.12 ? 485 ILE B CA  1 
ATOM 937  C C   . ILE A 1 176 ? 158.862 139.309 189.554 1.00 216.12 ? 485 ILE B C   1 
ATOM 938  O O   . ILE A 1 176 ? 159.936 139.714 189.089 1.00 216.12 ? 485 ILE B O   1 
ATOM 939  C CB  . ILE A 1 176 ? 157.941 139.248 187.191 1.00 216.12 ? 485 ILE B CB  1 
ATOM 940  C CG1 . ILE A 1 176 ? 156.650 139.111 186.399 1.00 216.12 ? 485 ILE B CG1 1 
ATOM 941  C CG2 . ILE A 1 176 ? 158.869 138.119 186.776 1.00 216.12 ? 485 ILE B CG2 1 
ATOM 942  C CD1 . ILE A 1 176 ? 156.737 139.654 185.023 1.00 216.12 ? 485 ILE B CD1 1 
ATOM 943  N N   . ALA A 1 177 ? 158.686 139.042 190.839 1.00 197.77 ? 486 ALA B N   1 
ATOM 944  C CA  . ALA A 1 177 ? 159.663 138.420 191.719 1.00 197.77 ? 486 ALA B CA  1 
ATOM 945  C C   . ALA A 1 177 ? 159.035 137.360 192.598 1.00 197.77 ? 486 ALA B C   1 
ATOM 946  O O   . ALA A 1 177 ? 159.740 136.438 193.026 1.00 197.77 ? 486 ALA B O   1 
ATOM 947  C CB  . ALA A 1 177 ? 160.333 139.469 192.611 1.00 197.77 ? 486 ALA B CB  1 
ATOM 948  N N   . LYS A 1 178 ? 157.727 137.440 192.857 1.00 215.80 ? 487 LYS B N   1 
ATOM 949  C CA  . LYS A 1 178 ? 157.063 136.460 193.710 1.00 215.80 ? 487 LYS B CA  1 
ATOM 950  C C   . LYS A 1 178 ? 157.004 135.091 193.042 1.00 215.80 ? 487 LYS B C   1 
ATOM 951  O O   . LYS A 1 178 ? 157.794 134.195 193.358 1.00 215.80 ? 487 LYS B O   1 
ATOM 952  C CB  . LYS A 1 178 ? 155.644 136.939 194.043 1.00 215.80 ? 487 LYS B CB  1 
ATOM 953  C CG  . LYS A 1 178 ? 155.509 138.257 194.811 1.00 215.80 ? 487 LYS B CG  1 
ATOM 954  C CD  . LYS A 1 178 ? 155.928 138.133 196.273 1.00 215.80 ? 487 LYS B CD  1 
ATOM 955  C CE  . LYS A 1 178 ? 157.373 138.527 196.505 1.00 215.80 ? 487 LYS B CE  1 
ATOM 956  N NZ  . LYS A 1 178 ? 157.720 138.508 197.954 1.00 215.80 ? 487 LYS B NZ  1 
ATOM 957  N N   . GLY A 1 179 ? 156.087 134.927 192.089 1.00 206.41 ? 488 GLY B N   1 
ATOM 958  C CA  . GLY A 1 179 ? 155.706 133.619 191.590 1.00 206.41 ? 488 GLY B CA  1 
ATOM 959  C C   . GLY A 1 179 ? 156.685 133.017 190.609 1.00 206.41 ? 488 GLY B C   1 
ATOM 960  O O   . GLY A 1 179 ? 157.098 131.863 190.754 1.00 206.41 ? 488 GLY B O   1 
ATOM 961  N N   . CYS A 1 180 ? 157.041 133.787 189.587 1.00 201.20 ? 489 CYS B N   1 
ATOM 962  C CA  . CYS A 1 180 ? 158.080 133.365 188.663 1.00 201.20 ? 489 CYS B CA  1 
ATOM 963  C C   . CYS A 1 180 ? 159.409 133.228 189.394 1.00 201.20 ? 489 CYS B C   1 
ATOM 964  O O   . CYS A 1 180 ? 159.756 134.063 190.236 1.00 201.20 ? 489 CYS B O   1 
ATOM 965  C CB  . CYS A 1 180 ? 158.201 134.376 187.528 1.00 201.20 ? 489 CYS B CB  1 
ATOM 966  S SG  . CYS A 1 180 ? 159.639 134.128 186.479 1.00 201.20 ? 489 CYS B SG  1 
ATOM 967  N N   . LEU A 1 181 ? 160.150 132.162 189.085 1.00 164.38 ? 490 LEU B N   1 
ATOM 968  C CA  . LEU A 1 181 ? 161.456 131.948 189.691 1.00 164.38 ? 490 LEU B CA  1 
ATOM 969  C C   . LEU A 1 181 ? 162.539 131.536 188.709 1.00 164.38 ? 490 LEU B C   1 
ATOM 970  O O   . LEU A 1 181 ? 163.714 131.754 189.004 1.00 164.38 ? 490 LEU B O   1 
ATOM 971  C CB  . LEU A 1 181 ? 161.365 130.894 190.811 1.00 164.38 ? 490 LEU B CB  1 
ATOM 972  C CG  . LEU A 1 181 ? 162.558 130.686 191.756 1.00 164.38 ? 490 LEU B CG  1 
ATOM 973  C CD1 . LEU A 1 181 ? 162.096 130.353 193.163 1.00 164.38 ? 490 LEU B CD1 1 
ATOM 974  C CD2 . LEU A 1 181 ? 163.517 129.607 191.260 1.00 164.38 ? 490 LEU B CD2 1 
ATOM 975  N N   . LYS A 1 182 ? 162.195 130.991 187.548 1.00 148.60 ? 491 LYS B N   1 
ATOM 976  C CA  . LYS A 1 182 ? 163.184 130.363 186.680 1.00 148.60 ? 491 LYS B CA  1 
ATOM 977  C C   . LYS A 1 182 ? 164.025 131.388 185.902 1.00 148.60 ? 491 LYS B C   1 
ATOM 978  O O   . LYS A 1 182 ? 164.761 131.018 184.982 1.00 148.60 ? 491 LYS B O   1 
ATOM 979  C CB  . LYS A 1 182 ? 162.466 129.379 185.740 1.00 148.60 ? 491 LYS B CB  1 
ATOM 980  C CG  . LYS A 1 182 ? 163.353 128.486 184.879 1.00 148.60 ? 491 LYS B CG  1 
ATOM 981  C CD  . LYS A 1 182 ? 164.411 127.770 185.719 1.00 148.60 ? 491 LYS B CD  1 
ATOM 982  C CE  . LYS A 1 182 ? 163.812 127.064 186.935 1.00 148.60 ? 491 LYS B CE  1 
ATOM 983  N NZ  . LYS A 1 182 ? 164.857 126.658 187.914 1.00 148.60 ? 491 LYS B NZ  1 
ATOM 984  N N   . LEU A 1 183 ? 163.960 132.659 186.291 1.00 121.95 ? 492 LEU B N   1 
ATOM 985  C CA  . LEU A 1 183 ? 164.648 133.735 185.589 1.00 121.95 ? 492 LEU B CA  1 
ATOM 986  C C   . LEU A 1 183 ? 166.156 133.501 185.506 1.00 121.95 ? 492 LEU B C   1 
ATOM 987  O O   . LEU A 1 183 ? 166.756 132.894 186.397 1.00 121.95 ? 492 LEU B O   1 
ATOM 988  C CB  . LEU A 1 183 ? 164.364 135.050 186.301 1.00 121.95 ? 492 LEU B CB  1 
ATOM 989  C CG  . LEU A 1 183 ? 164.932 136.328 185.712 1.00 121.95 ? 492 LEU B CG  1 
ATOM 990  C CD1 . LEU A 1 183 ? 164.362 136.585 184.335 1.00 121.95 ? 492 LEU B CD1 1 
ATOM 991  C CD2 . LEU A 1 183 ? 164.598 137.454 186.650 1.00 121.95 ? 492 LEU B CD2 1 
ATOM 992  N N   . GLN A 1 184 ? 166.762 133.948 184.405 1.00 97.63  ? 493 GLN B N   1 
ATOM 993  C CA  . GLN A 1 184 ? 168.206 133.827 184.236 1.00 97.63  ? 493 GLN B CA  1 
ATOM 994  C C   . GLN A 1 184 ? 168.931 135.132 183.932 1.00 97.63  ? 493 GLN B C   1 
ATOM 995  O O   . GLN A 1 184 ? 169.975 135.399 184.536 1.00 97.63  ? 493 GLN B O   1 
ATOM 996  C CB  . GLN A 1 184 ? 168.519 132.798 183.146 1.00 97.63  ? 493 GLN B CB  1 
ATOM 997  C CG  . GLN A 1 184 ? 168.375 131.375 183.644 1.00 97.63  ? 493 GLN B CG  1 
ATOM 998  C CD  . GLN A 1 184 ? 169.002 130.361 182.719 1.00 97.63  ? 493 GLN B CD  1 
ATOM 999  O OE1 . GLN A 1 184 ? 169.557 130.712 181.680 1.00 97.63  ? 493 GLN B OE1 1 
ATOM 1000 N NE2 . GLN A 1 184 ? 168.915 129.091 183.090 1.00 97.63  ? 493 GLN B NE2 1 
ATOM 1001 N N   . ARG A 1 185 ? 168.432 135.948 183.004 1.00 93.54  ? 494 ARG B N   1 
ATOM 1002 C CA  . ARG A 1 185 ? 169.126 137.152 182.562 1.00 93.54  ? 494 ARG B CA  1 
ATOM 1003 C C   . ARG A 1 185 ? 168.333 138.398 182.945 1.00 93.54  ? 494 ARG B C   1 
ATOM 1004 O O   . ARG A 1 185 ? 167.105 138.420 182.822 1.00 93.54  ? 494 ARG B O   1 
ATOM 1005 C CB  . ARG A 1 185 ? 169.338 137.132 181.050 1.00 93.54  ? 494 ARG B CB  1 
ATOM 1006 C CG  . ARG A 1 185 ? 170.477 136.248 180.582 1.00 93.54  ? 494 ARG B CG  1 
ATOM 1007 C CD  . ARG A 1 185 ? 170.787 136.438 179.102 1.00 93.54  ? 494 ARG B CD  1 
ATOM 1008 N NE  . ARG A 1 185 ? 171.024 135.169 178.425 1.00 93.54  ? 494 ARG B NE  1 
ATOM 1009 C CZ  . ARG A 1 185 ? 172.162 134.491 178.482 1.00 93.54  ? 494 ARG B CZ  1 
ATOM 1010 N N   . ILE A 1 186 ? 169.040 139.439 183.390 1.00 78.19  ? 495 ILE B N   1 
ATOM 1011 C CA  . ILE A 1 186 ? 168.433 140.714 183.766 1.00 78.19  ? 495 ILE B CA  1 
ATOM 1012 C C   . ILE A 1 186 ? 169.134 141.851 183.038 1.00 78.19  ? 495 ILE B C   1 
ATOM 1013 O O   . ILE A 1 186 ? 170.363 141.956 183.078 1.00 78.19  ? 495 ILE B O   1 
ATOM 1014 C CB  . ILE A 1 186 ? 168.484 140.951 185.285 1.00 78.19  ? 495 ILE B CB  1 
ATOM 1015 C CG1 . ILE A 1 186 ? 167.439 140.090 185.968 1.00 78.19  ? 495 ILE B CG1 1 
ATOM 1016 C CG2 . ILE A 1 186 ? 168.280 142.409 185.609 1.00 78.19  ? 495 ILE B CG2 1 
ATOM 1017 C CD1 . ILE A 1 186 ? 166.070 140.401 185.487 1.00 78.19  ? 495 ILE B CD1 1 
ATOM 1018 N N   . TYR A 1 187 ? 168.349 142.705 182.385 1.00 84.08  ? 496 TYR B N   1 
ATOM 1019 C CA  . TYR A 1 187 ? 168.849 143.919 181.763 1.00 84.08  ? 496 TYR B CA  1 
ATOM 1020 C C   . TYR A 1 187 ? 167.750 144.971 181.761 1.00 84.08  ? 496 TYR B C   1 
ATOM 1021 O O   . TYR A 1 187 ? 166.628 144.709 181.318 1.00 84.08  ? 496 TYR B O   1 
ATOM 1022 C CB  . TYR A 1 187 ? 169.343 143.651 180.336 1.00 84.08  ? 496 TYR B CB  1 
ATOM 1023 C CG  . TYR A 1 187 ? 170.005 144.837 179.669 1.00 84.08  ? 496 TYR B CG  1 
ATOM 1024 C CD1 . TYR A 1 187 ? 169.254 145.782 178.989 1.00 84.08  ? 496 TYR B CD1 1 
ATOM 1025 C CD2 . TYR A 1 187 ? 171.379 145.014 179.721 1.00 84.08  ? 496 TYR B CD2 1 
ATOM 1026 C CE1 . TYR A 1 187 ? 169.844 146.853 178.374 1.00 84.08  ? 496 TYR B CE1 1 
ATOM 1027 C CE2 . TYR A 1 187 ? 171.980 146.095 179.110 1.00 84.08  ? 496 TYR B CE2 1 
ATOM 1028 C CZ  . TYR A 1 187 ? 171.206 147.011 178.438 1.00 84.08  ? 496 TYR B CZ  1 
ATOM 1029 N N   . MET A 1 188 ? 168.083 146.159 182.267 1.00 92.03  ? 497 MET B N   1 
ATOM 1030 C CA  . MET A 1 188 ? 167.196 147.313 182.252 1.00 92.03  ? 497 MET B CA  1 
ATOM 1031 C C   . MET A 1 188 ? 167.985 148.507 181.725 1.00 92.03  ? 497 MET B C   1 
ATOM 1032 O O   . MET A 1 188 ? 169.178 148.398 181.425 1.00 92.03  ? 497 MET B O   1 
ATOM 1033 C CB  . MET A 1 188 ? 166.630 147.593 183.645 1.00 92.03  ? 497 MET B CB  1 
ATOM 1034 C CG  . MET A 1 188 ? 165.605 146.576 184.119 1.00 92.03  ? 497 MET B CG  1 
ATOM 1035 S SD  . MET A 1 188 ? 164.321 146.173 182.925 1.00 92.03  ? 497 MET B SD  1 
ATOM 1036 C CE  . MET A 1 188 ? 163.102 145.444 184.017 1.00 92.03  ? 497 MET B CE  1 
ATOM 1037 N N   . GLN A 1 189 ? 167.335 149.662 181.648 1.00 95.34  ? 498 GLN B N   1 
ATOM 1038 C CA  . GLN A 1 189 ? 167.933 150.849 181.035 1.00 95.34  ? 498 GLN B CA  1 
ATOM 1039 C C   . GLN A 1 189 ? 167.682 152.034 181.957 1.00 95.34  ? 498 GLN B C   1 
ATOM 1040 O O   . GLN A 1 189 ? 167.283 151.873 183.115 1.00 95.34  ? 498 GLN B O   1 
ATOM 1041 C CB  . GLN A 1 189 ? 167.387 151.074 179.616 1.00 95.34  ? 498 GLN B CB  1 
ATOM 1042 C CG  . GLN A 1 189 ? 168.341 151.818 178.685 1.00 95.34  ? 498 GLN B CG  1 
ATOM 1043 C CD  . GLN A 1 189 ? 169.348 150.915 178.011 1.00 95.34  ? 498 GLN B CD  1 
ATOM 1044 O OE1 . GLN A 1 189 ? 169.521 149.766 178.401 1.00 95.34  ? 498 GLN B OE1 1 
ATOM 1045 N NE2 . GLN A 1 189 ? 170.028 151.436 176.997 1.00 95.34  ? 498 GLN B NE2 1 
ATOM 1046 N N   . GLU A 1 190 ? 167.916 153.246 181.455 1.00 114.64 ? 499 GLU B N   1 
ATOM 1047 C CA  . GLU A 1 190 ? 167.769 154.427 182.293 1.00 114.64 ? 499 GLU B CA  1 
ATOM 1048 C C   . GLU A 1 190 ? 166.302 154.639 182.626 1.00 114.64 ? 499 GLU B C   1 
ATOM 1049 O O   . GLU A 1 190 ? 165.673 155.593 182.156 1.00 114.64 ? 499 GLU B O   1 
ATOM 1050 C CB  . GLU A 1 190 ? 168.350 155.669 181.615 1.00 114.64 ? 499 GLU B CB  1 
ATOM 1051 C CG  . GLU A 1 190 ? 169.757 155.486 181.087 1.00 114.64 ? 499 GLU B CG  1 
ATOM 1052 C CD  . GLU A 1 190 ? 170.167 156.566 180.106 1.00 114.64 ? 499 GLU B CD  1 
ATOM 1053 O OE1 . GLU A 1 190 ? 170.299 156.260 178.901 1.00 114.64 ? 499 GLU B OE1 1 
ATOM 1054 O OE2 . GLU A 1 190 ? 170.366 157.719 180.540 1.00 114.64 ? 499 GLU B OE2 1 
ATOM 1055 N N   . ASN A 1 191 ? 165.759 153.742 183.441 1.00 156.55 ? 500 ASN B N   1 
ATOM 1056 C CA  . ASN A 1 191 ? 164.376 153.790 183.889 1.00 156.55 ? 500 ASN B CA  1 
ATOM 1057 C C   . ASN A 1 191 ? 164.397 154.233 185.346 1.00 156.55 ? 500 ASN B C   1 
ATOM 1058 O O   . ASN A 1 191 ? 164.775 153.458 186.231 1.00 156.55 ? 500 ASN B O   1 
ATOM 1059 C CB  . ASN A 1 191 ? 163.711 152.425 183.717 1.00 156.55 ? 500 ASN B CB  1 
ATOM 1060 C CG  . ASN A 1 191 ? 162.251 152.430 184.102 1.00 156.55 ? 500 ASN B CG  1 
ATOM 1061 O OD1 . ASN A 1 191 ? 161.748 153.384 184.692 1.00 156.55 ? 500 ASN B OD1 1 
ATOM 1062 N ND2 . ASN A 1 191 ? 161.557 151.356 183.761 1.00 156.55 ? 500 ASN B ND2 1 
ATOM 1063 N N   . LYS A 1 192 ? 163.990 155.475 185.588 1.00 134.00 ? 501 LYS B N   1 
ATOM 1064 C CA  . LYS A 1 192 ? 164.008 156.020 186.933 1.00 134.00 ? 501 LYS B CA  1 
ATOM 1065 C C   . LYS A 1 192 ? 162.840 155.495 187.754 1.00 134.00 ? 501 LYS B C   1 
ATOM 1066 O O   . LYS A 1 192 ? 162.026 154.684 187.301 1.00 134.00 ? 501 LYS B O   1 
ATOM 1067 C CB  . LYS A 1 192 ? 163.970 157.546 186.905 1.00 134.00 ? 501 LYS B CB  1 
ATOM 1068 C CG  . LYS A 1 192 ? 165.216 158.191 186.356 1.00 134.00 ? 501 LYS B CG  1 
ATOM 1069 C CD  . LYS A 1 192 ? 166.447 157.493 186.898 1.00 134.00 ? 501 LYS B CD  1 
ATOM 1070 C CE  . LYS A 1 192 ? 167.688 157.896 186.137 1.00 134.00 ? 501 LYS B CE  1 
ATOM 1071 N NZ  . LYS A 1 192 ? 168.878 157.902 187.028 1.00 134.00 ? 501 LYS B NZ  1 
ATOM 1072 N N   . LEU A 1 193 ? 162.786 155.969 188.995 1.00 146.24 ? 502 LEU B N   1 
ATOM 1073 C CA  . LEU A 1 193 ? 161.778 155.633 189.991 1.00 146.24 ? 502 LEU B CA  1 
ATOM 1074 C C   . LEU A 1 193 ? 161.837 154.172 190.405 1.00 146.24 ? 502 LEU B C   1 
ATOM 1075 O O   . LEU A 1 193 ? 161.122 153.772 191.328 1.00 146.24 ? 502 LEU B O   1 
ATOM 1076 C CB  . LEU A 1 193 ? 160.366 155.977 189.507 1.00 146.24 ? 502 LEU B CB  1 
ATOM 1077 C CG  . LEU A 1 193 ? 159.913 157.428 189.682 1.00 146.24 ? 502 LEU B CG  1 
ATOM 1078 C CD1 . LEU A 1 193 ? 160.599 158.347 188.679 1.00 146.24 ? 502 LEU B CD1 1 
ATOM 1079 C CD2 . LEU A 1 193 ? 158.400 157.524 189.554 1.00 146.24 ? 502 LEU B CD2 1 
ATOM 1080 N N   . VAL A 1 194 ? 162.692 153.369 189.778 1.00 131.69 ? 503 VAL B N   1 
ATOM 1081 C CA  . VAL A 1 194 ? 162.944 152.012 190.234 1.00 131.69 ? 503 VAL B CA  1 
ATOM 1082 C C   . VAL A 1 194 ? 163.815 152.161 191.474 1.00 131.69 ? 503 VAL B C   1 
ATOM 1083 O O   . VAL A 1 194 ? 165.030 152.333 191.382 1.00 131.69 ? 503 VAL B O   1 
ATOM 1084 C CB  . VAL A 1 194 ? 163.613 151.157 189.159 1.00 131.69 ? 503 VAL B CB  1 
ATOM 1085 C CG1 . VAL A 1 194 ? 163.979 149.797 189.726 1.00 131.69 ? 503 VAL B CG1 1 
ATOM 1086 C CG2 . VAL A 1 194 ? 162.703 151.015 187.956 1.00 131.69 ? 503 VAL B CG2 1 
ATOM 1087 N N   . THR A 1 195 ? 163.184 152.125 192.638 1.00 142.89 ? 504 THR B N   1 
ATOM 1088 C CA  . THR A 1 195 ? 163.881 152.416 193.879 1.00 142.89 ? 504 THR B CA  1 
ATOM 1089 C C   . THR A 1 195 ? 164.747 151.226 194.270 1.00 142.89 ? 504 THR B C   1 
ATOM 1090 O O   . THR A 1 195 ? 164.848 150.229 193.552 1.00 142.89 ? 504 THR B O   1 
ATOM 1091 C CB  . THR A 1 195 ? 162.883 152.773 194.974 1.00 142.89 ? 504 THR B CB  1 
ATOM 1092 O OG1 . THR A 1 195 ? 163.590 153.261 196.121 1.00 142.89 ? 504 THR B OG1 1 
ATOM 1093 C CG2 . THR A 1 195 ? 162.075 151.552 195.366 1.00 142.89 ? 504 THR B CG2 1 
ATOM 1094 N N   . ASP A 1 196 ? 165.359 151.313 195.445 1.00 126.82 ? 505 ASP B N   1 
ATOM 1095 C CA  . ASP A 1 196 ? 166.268 150.289 195.933 1.00 126.82 ? 505 ASP B CA  1 
ATOM 1096 C C   . ASP A 1 196 ? 165.539 149.038 196.404 1.00 126.82 ? 505 ASP B C   1 
ATOM 1097 O O   . ASP A 1 196 ? 166.185 148.108 196.893 1.00 126.82 ? 505 ASP B O   1 
ATOM 1098 C CB  . ASP A 1 196 ? 167.118 150.853 197.068 1.00 126.82 ? 505 ASP B CB  1 
ATOM 1099 C CG  . ASP A 1 196 ? 168.400 150.102 197.246 1.00 126.82 ? 505 ASP B CG  1 
ATOM 1100 O OD1 . ASP A 1 196 ? 168.641 149.180 196.450 1.00 126.82 ? 505 ASP B OD1 1 
ATOM 1101 O OD2 . ASP A 1 196 ? 169.157 150.415 198.181 1.00 126.82 ? 505 ASP B OD2 1 
ATOM 1102 N N   . GLN A 1 197 ? 164.214 149.008 196.294 1.00 172.41 ? 506 GLN B N   1 
ATOM 1103 C CA  . GLN A 1 197 ? 163.401 147.866 196.685 1.00 172.41 ? 506 GLN B CA  1 
ATOM 1104 C C   . GLN A 1 197 ? 163.474 146.725 195.678 1.00 172.41 ? 506 GLN B C   1 
ATOM 1105 O O   . GLN A 1 197 ? 163.065 145.601 195.988 1.00 172.41 ? 506 GLN B O   1 
ATOM 1106 C CB  . GLN A 1 197 ? 161.948 148.304 196.869 1.00 172.41 ? 506 GLN B CB  1 
ATOM 1107 C CG  . GLN A 1 197 ? 161.103 147.418 197.783 1.00 172.41 ? 506 GLN B CG  1 
ATOM 1108 C CD  . GLN A 1 197 ? 161.590 147.407 199.223 1.00 172.41 ? 506 GLN B CD  1 
ATOM 1109 O OE1 . GLN A 1 197 ? 162.658 146.882 199.536 1.00 172.41 ? 506 GLN B OE1 1 
ATOM 1110 N NE2 . GLN A 1 197 ? 160.794 147.991 200.114 1.00 172.41 ? 506 GLN B NE2 1 
ATOM 1111 N N   . SER A 1 198 ? 163.995 146.987 194.484 1.00 155.93 ? 507 SER B N   1 
ATOM 1112 C CA  . SER A 1 198 ? 164.072 145.980 193.442 1.00 155.93 ? 507 SER B CA  1 
ATOM 1113 C C   . SER A 1 198 ? 165.378 145.214 193.470 1.00 155.93 ? 507 SER B C   1 
ATOM 1114 O O   . SER A 1 198 ? 165.663 144.474 192.527 1.00 155.93 ? 507 SER B O   1 
ATOM 1115 C CB  . SER A 1 198 ? 163.897 146.623 192.060 1.00 155.93 ? 507 SER B CB  1 
ATOM 1116 O OG  . SER A 1 198 ? 164.277 145.727 191.031 1.00 155.93 ? 507 SER B OG  1 
ATOM 1117 N N   . VAL A 1 199 ? 166.189 145.388 194.505 1.00 134.69 ? 508 VAL B N   1 
ATOM 1118 C CA  . VAL A 1 199 ? 167.500 144.765 194.598 1.00 134.69 ? 508 VAL B CA  1 
ATOM 1119 C C   . VAL A 1 199 ? 167.634 143.952 195.879 1.00 134.69 ? 508 VAL B C   1 
ATOM 1120 O O   . VAL A 1 199 ? 167.988 142.770 195.846 1.00 134.69 ? 508 VAL B O   1 
ATOM 1121 C CB  . VAL A 1 199 ? 168.623 145.815 194.502 1.00 134.69 ? 508 VAL B CB  1 
ATOM 1122 C CG1 . VAL A 1 199 ? 169.963 145.153 194.646 1.00 134.69 ? 508 VAL B CG1 1 
ATOM 1123 C CG2 . VAL A 1 199 ? 168.522 146.571 193.200 1.00 134.69 ? 508 VAL B CG2 1 
ATOM 1124 N N   . LYS A 1 200 ? 167.355 144.578 197.022 1.00 141.43 ? 509 LYS B N   1 
ATOM 1125 C CA  . LYS A 1 200 ? 167.238 143.833 198.268 1.00 141.43 ? 509 LYS B CA  1 
ATOM 1126 C C   . LYS A 1 200 ? 166.249 142.688 198.127 1.00 141.43 ? 509 LYS B C   1 
ATOM 1127 O O   . LYS A 1 200 ? 166.570 141.536 198.440 1.00 141.43 ? 509 LYS B O   1 
ATOM 1128 C CB  . LYS A 1 200 ? 166.801 144.783 199.383 1.00 141.43 ? 509 LYS B CB  1 
ATOM 1129 C CG  . LYS A 1 200 ? 166.626 144.143 200.737 1.00 141.43 ? 509 LYS B CG  1 
ATOM 1130 C CD  . LYS A 1 200 ? 165.157 143.906 201.027 1.00 141.43 ? 509 LYS B CD  1 
ATOM 1131 C CE  . LYS A 1 200 ? 164.949 143.359 202.421 1.00 141.43 ? 509 LYS B CE  1 
ATOM 1132 N NZ  . LYS A 1 200 ? 163.507 143.113 202.689 1.00 141.43 ? 509 LYS B NZ  1 
ATOM 1133 N N   . ALA A 1 201 ? 165.057 142.981 197.620 1.00 143.93 ? 510 ALA B N   1 
ATOM 1134 C CA  . ALA A 1 201 ? 163.984 142.005 197.532 1.00 143.93 ? 510 ALA B CA  1 
ATOM 1135 C C   . ALA A 1 201 ? 164.124 141.061 196.350 1.00 143.93 ? 510 ALA B C   1 
ATOM 1136 O O   . ALA A 1 201 ? 163.442 140.032 196.314 1.00 143.93 ? 510 ALA B O   1 
ATOM 1137 C CB  . ALA A 1 201 ? 162.633 142.719 197.443 1.00 143.93 ? 510 ALA B CB  1 
ATOM 1138 N N   . PHE A 1 202 ? 164.984 141.372 195.390 1.00 128.26 ? 511 PHE B N   1 
ATOM 1139 C CA  . PHE A 1 202 ? 165.050 140.583 194.174 1.00 128.26 ? 511 PHE B CA  1 
ATOM 1140 C C   . PHE A 1 202 ? 166.116 139.509 194.225 1.00 128.26 ? 511 PHE B C   1 
ATOM 1141 O O   . PHE A 1 202 ? 166.063 138.567 193.430 1.00 128.26 ? 511 PHE B O   1 
ATOM 1142 C CB  . PHE A 1 202 ? 165.301 141.487 192.973 1.00 128.26 ? 511 PHE B CB  1 
ATOM 1143 C CG  . PHE A 1 202 ? 164.769 140.939 191.696 1.00 128.26 ? 511 PHE B CG  1 
ATOM 1144 C CD1 . PHE A 1 202 ? 165.558 140.875 190.572 1.00 128.26 ? 511 PHE B CD1 1 
ATOM 1145 C CD2 . PHE A 1 202 ? 163.467 140.483 191.625 1.00 128.26 ? 511 PHE B CD2 1 
ATOM 1146 C CE1 . PHE A 1 202 ? 165.053 140.370 189.397 1.00 128.26 ? 511 PHE B CE1 1 
ATOM 1147 C CE2 . PHE A 1 202 ? 162.958 139.978 190.454 1.00 128.26 ? 511 PHE B CE2 1 
ATOM 1148 C CZ  . PHE A 1 202 ? 163.748 139.921 189.340 1.00 128.26 ? 511 PHE B CZ  1 
ATOM 1149 N N   . ALA A 1 203 ? 167.077 139.628 195.133 1.00 138.50 ? 512 ALA B N   1 
ATOM 1150 C CA  . ALA A 1 203 ? 168.020 138.561 195.405 1.00 138.50 ? 512 ALA B CA  1 
ATOM 1151 C C   . ALA A 1 203 ? 167.492 137.619 196.473 1.00 138.50 ? 512 ALA B C   1 
ATOM 1152 O O   . ALA A 1 203 ? 168.193 136.683 196.870 1.00 138.50 ? 512 ALA B O   1 
ATOM 1153 C CB  . ALA A 1 203 ? 169.371 139.141 195.823 1.00 138.50 ? 512 ALA B CB  1 
ATOM 1154 N N   . GLU A 1 204 ? 166.260 137.845 196.935 1.00 134.11 ? 513 GLU B N   1 
ATOM 1155 C CA  . GLU A 1 204 ? 165.649 137.038 197.977 1.00 134.11 ? 513 GLU B CA  1 
ATOM 1156 C C   . GLU A 1 204 ? 165.067 135.731 197.473 1.00 134.11 ? 513 GLU B C   1 
ATOM 1157 O O   . GLU A 1 204 ? 165.119 134.733 198.196 1.00 134.11 ? 513 GLU B O   1 
ATOM 1158 C CB  . GLU A 1 204 ? 164.513 137.816 198.658 1.00 134.11 ? 513 GLU B CB  1 
ATOM 1159 C CG  . GLU A 1 204 ? 164.908 139.111 199.343 1.00 134.11 ? 513 GLU B CG  1 
ATOM 1160 C CD  . GLU A 1 204 ? 165.762 138.899 200.567 1.00 134.11 ? 513 GLU B CD  1 
ATOM 1161 O OE1 . GLU A 1 204 ? 165.570 137.876 201.252 1.00 134.11 ? 513 GLU B OE1 1 
ATOM 1162 O OE2 . GLU A 1 204 ? 166.621 139.760 200.850 1.00 134.11 ? 513 GLU B OE2 1 
ATOM 1163 N N   . HIS A 1 205 ? 164.541 135.704 196.252 1.00 175.93 ? 514 HIS B N   1 
ATOM 1164 C CA  . HIS A 1 205 ? 163.627 134.659 195.816 1.00 175.93 ? 514 HIS B CA  1 
ATOM 1165 C C   . HIS A 1 205 ? 164.274 133.624 194.910 1.00 175.93 ? 514 HIS B C   1 
ATOM 1166 O O   . HIS A 1 205 ? 164.354 132.443 195.266 1.00 175.93 ? 514 HIS B O   1 
ATOM 1167 C CB  . HIS A 1 205 ? 162.451 135.313 195.082 1.00 175.93 ? 514 HIS B CB  1 
ATOM 1168 C CG  . HIS A 1 205 ? 161.504 136.031 195.987 1.00 175.93 ? 514 HIS B CG  1 
ATOM 1169 N ND1 . HIS A 1 205 ? 160.540 135.380 196.726 1.00 175.93 ? 514 HIS B ND1 1 
ATOM 1170 C CD2 . HIS A 1 205 ? 161.398 137.343 196.302 1.00 175.93 ? 514 HIS B CD2 1 
ATOM 1171 C CE1 . HIS A 1 205 ? 159.866 136.264 197.439 1.00 175.93 ? 514 HIS B CE1 1 
ATOM 1172 N NE2 . HIS A 1 205 ? 160.370 137.462 197.203 1.00 175.93 ? 514 HIS B NE2 1 
ATOM 1173 N N   . CYS A 1 206 ? 164.745 134.047 193.745 1.00 143.50 ? 515 CYS B N   1 
ATOM 1174 C CA  . CYS A 1 206 ? 165.311 133.155 192.744 1.00 143.50 ? 515 CYS B CA  1 
ATOM 1175 C C   . CYS A 1 206 ? 166.805 133.405 192.606 1.00 143.50 ? 515 CYS B C   1 
ATOM 1176 O O   . CYS A 1 206 ? 167.212 134.399 191.985 1.00 143.50 ? 515 CYS B O   1 
ATOM 1177 C CB  . CYS A 1 206 ? 164.587 133.357 191.413 1.00 143.50 ? 515 CYS B CB  1 
ATOM 1178 S SG  . CYS A 1 206 ? 164.543 135.038 190.765 1.00 143.50 ? 515 CYS B SG  1 
ATOM 1179 N N   . PRO A 1 207 ? 167.655 132.546 193.163 1.00 119.11 ? 516 PRO B N   1 
ATOM 1180 C CA  . PRO A 1 207 ? 169.089 132.867 193.289 1.00 119.11 ? 516 PRO B CA  1 
ATOM 1181 C C   . PRO A 1 207 ? 169.962 132.397 192.132 1.00 119.11 ? 516 PRO B C   1 
ATOM 1182 O O   . PRO A 1 207 ? 171.189 132.434 192.276 1.00 119.11 ? 516 PRO B O   1 
ATOM 1183 C CB  . PRO A 1 207 ? 169.461 132.121 194.572 1.00 119.11 ? 516 PRO B CB  1 
ATOM 1184 C CG  . PRO A 1 207 ? 168.603 130.886 194.526 1.00 119.11 ? 516 PRO B CG  1 
ATOM 1185 C CD  . PRO A 1 207 ? 167.340 131.233 193.753 1.00 119.11 ? 516 PRO B CD  1 
ATOM 1186 N N   . GLU A 1 208 ? 169.382 131.952 191.020 1.00 107.91 ? 517 GLU B N   1 
ATOM 1187 C CA  . GLU A 1 208 ? 170.153 131.365 189.936 1.00 107.91 ? 517 GLU B CA  1 
ATOM 1188 C C   . GLU A 1 208 ? 170.450 132.361 188.820 1.00 107.91 ? 517 GLU B C   1 
ATOM 1189 O O   . GLU A 1 208 ? 171.060 131.989 187.813 1.00 107.91 ? 517 GLU B O   1 
ATOM 1190 C CB  . GLU A 1 208 ? 169.411 130.160 189.372 1.00 107.91 ? 517 GLU B CB  1 
ATOM 1191 C CG  . GLU A 1 208 ? 168.330 130.544 188.398 1.00 107.91 ? 517 GLU B CG  1 
ATOM 1192 C CD  . GLU A 1 208 ? 166.995 130.728 189.053 1.00 107.91 ? 517 GLU B CD  1 
ATOM 1193 O OE1 . GLU A 1 208 ? 166.912 130.646 190.297 1.00 107.91 ? 517 GLU B OE1 1 
ATOM 1194 O OE2 . GLU A 1 208 ? 166.025 130.939 188.308 1.00 107.91 ? 517 GLU B OE2 1 
ATOM 1195 N N   . LEU A 1 209 ? 170.049 133.617 188.984 1.00 93.73  ? 518 LEU B N   1 
ATOM 1196 C CA  . LEU A 1 209 ? 170.193 134.592 187.914 1.00 93.73  ? 518 LEU B CA  1 
ATOM 1197 C C   . LEU A 1 209 ? 171.663 134.799 187.578 1.00 93.73  ? 518 LEU B C   1 
ATOM 1198 O O   . LEU A 1 209 ? 172.534 134.780 188.450 1.00 93.73  ? 518 LEU B O   1 
ATOM 1199 C CB  . LEU A 1 209 ? 169.548 135.913 188.320 1.00 93.73  ? 518 LEU B CB  1 
ATOM 1200 C CG  . LEU A 1 209 ? 168.073 136.062 187.961 1.00 93.73  ? 518 LEU B CG  1 
ATOM 1201 C CD1 . LEU A 1 209 ? 167.259 135.012 188.666 1.00 93.73  ? 518 LEU B CD1 1 
ATOM 1202 C CD2 . LEU A 1 209 ? 167.592 137.437 188.362 1.00 93.73  ? 518 LEU B CD2 1 
ATOM 1203 N N   . GLN A 1 210 ? 171.938 134.994 186.298 1.00 82.50  ? 519 GLN B N   1 
ATOM 1204 C CA  . GLN A 1 210 ? 173.313 135.101 185.831 1.00 82.50  ? 519 GLN B CA  1 
ATOM 1205 C C   . GLN A 1 210 ? 173.658 136.460 185.247 1.00 82.50  ? 519 GLN B C   1 
ATOM 1206 O O   . GLN A 1 210 ? 174.806 136.895 185.352 1.00 82.50  ? 519 GLN B O   1 
ATOM 1207 C CB  . GLN A 1 210 ? 173.601 134.012 184.791 1.00 82.50  ? 519 GLN B CB  1 
ATOM 1208 C CG  . GLN A 1 210 ? 173.318 132.599 185.267 1.00 82.50  ? 519 GLN B CG  1 
ATOM 1209 C CD  . GLN A 1 210 ? 171.941 132.134 184.883 1.00 82.50  ? 519 GLN B CD  1 
ATOM 1210 O OE1 . GLN A 1 210 ? 170.980 132.884 185.005 1.00 82.50  ? 519 GLN B OE1 1 
ATOM 1211 N NE2 . GLN A 1 210 ? 171.832 130.897 184.409 1.00 82.50  ? 519 GLN B NE2 1 
ATOM 1212 N N   . TYR A 1 211 ? 172.705 137.141 184.626 1.00 72.65  ? 520 TYR B N   1 
ATOM 1213 C CA  . TYR A 1 211 ? 172.939 138.452 184.045 1.00 72.65  ? 520 TYR B CA  1 
ATOM 1214 C C   . TYR A 1 211 ? 172.063 139.482 184.746 1.00 72.65  ? 520 TYR B C   1 
ATOM 1215 O O   . TYR A 1 211 ? 170.878 139.232 184.970 1.00 72.65  ? 520 TYR B O   1 
ATOM 1216 C CB  . TYR A 1 211 ? 172.658 138.429 182.547 1.00 72.65  ? 520 TYR B CB  1 
ATOM 1217 C CG  . TYR A 1 211 ? 173.658 137.617 181.758 1.00 72.65  ? 520 TYR B CG  1 
ATOM 1218 C CD1 . TYR A 1 211 ? 173.576 136.236 181.698 1.00 72.65  ? 520 TYR B CD1 1 
ATOM 1219 C CD2 . TYR A 1 211 ? 174.679 138.239 181.060 1.00 72.65  ? 520 TYR B CD2 1 
ATOM 1220 C CE1 . TYR A 1 211 ? 174.484 135.497 180.967 1.00 72.65  ? 520 TYR B CE1 1 
ATOM 1221 C CE2 . TYR A 1 211 ? 175.597 137.509 180.332 1.00 72.65  ? 520 TYR B CE2 1 
ATOM 1222 C CZ  . TYR A 1 211 ? 175.495 136.137 180.289 1.00 72.65  ? 520 TYR B CZ  1 
ATOM 1223 N N   . VAL A 1 212 ? 172.657 140.621 185.110 1.00 74.87  ? 521 VAL B N   1 
ATOM 1224 C CA  . VAL A 1 212 ? 171.984 141.689 185.848 1.00 74.87  ? 521 VAL B CA  1 
ATOM 1225 C C   . VAL A 1 212 ? 172.260 143.023 185.167 1.00 74.87  ? 521 VAL B C   1 
ATOM 1226 O O   . VAL A 1 212 ? 173.422 143.419 185.018 1.00 74.87  ? 521 VAL B O   1 
ATOM 1227 C CB  . VAL A 1 212 ? 172.441 141.736 187.312 1.00 74.87  ? 521 VAL B CB  1 
ATOM 1228 C CG1 . VAL A 1 212 ? 172.173 143.093 187.892 1.00 74.87  ? 521 VAL B CG1 1 
ATOM 1229 C CG2 . VAL A 1 212 ? 171.697 140.703 188.108 1.00 74.87  ? 521 VAL B CG2 1 
ATOM 1230 N N   . GLY A 1 213 ? 171.194 143.737 184.794 1.00 82.97  ? 522 GLY B N   1 
ATOM 1231 C CA  . GLY A 1 213 ? 171.342 145.013 184.112 1.00 82.97  ? 522 GLY B CA  1 
ATOM 1232 C C   . GLY A 1 213 ? 170.648 146.206 184.749 1.00 82.97  ? 522 GLY B C   1 
ATOM 1233 O O   . GLY A 1 213 ? 169.418 146.307 184.722 1.00 82.97  ? 522 GLY B O   1 
ATOM 1234 N N   . PHE A 1 214 ? 171.434 147.144 185.280 1.00 93.52  ? 523 PHE B N   1 
ATOM 1235 C CA  . PHE A 1 214 ? 170.948 148.288 186.051 1.00 93.52  ? 523 PHE B CA  1 
ATOM 1236 C C   . PHE A 1 214 ? 171.655 149.574 185.651 1.00 93.52  ? 523 PHE B C   1 
ATOM 1237 O O   . PHE A 1 214 ? 172.231 150.275 186.485 1.00 93.52  ? 523 PHE B O   1 
ATOM 1238 C CB  . PHE A 1 214 ? 171.109 148.056 187.549 1.00 93.52  ? 523 PHE B CB  1 
ATOM 1239 C CG  . PHE A 1 214 ? 170.206 147.003 188.088 1.00 93.52  ? 523 PHE B CG  1 
ATOM 1240 C CD1 . PHE A 1 214 ? 168.902 146.922 187.644 1.00 93.52  ? 523 PHE B CD1 1 
ATOM 1241 C CD2 . PHE A 1 214 ? 170.646 146.105 189.037 1.00 93.52  ? 523 PHE B CD2 1 
ATOM 1242 C CE1 . PHE A 1 214 ? 168.051 145.960 188.127 1.00 93.52  ? 523 PHE B CE1 1 
ATOM 1243 C CE2 . PHE A 1 214 ? 169.800 145.136 189.527 1.00 93.52  ? 523 PHE B CE2 1 
ATOM 1244 C CZ  . PHE A 1 214 ? 168.499 145.063 189.070 1.00 93.52  ? 523 PHE B CZ  1 
ATOM 1245 N N   . MET A 1 215 ? 171.676 149.884 184.359 1.00 86.64  ? 524 MET B N   1 
ATOM 1246 C CA  . MET A 1 215 ? 172.274 151.141 183.939 1.00 86.64  ? 524 MET B CA  1 
ATOM 1247 C C   . MET A 1 215 ? 171.236 152.254 184.012 1.00 86.64  ? 524 MET B C   1 
ATOM 1248 O O   . MET A 1 215 ? 170.090 152.083 183.590 1.00 86.64  ? 524 MET B O   1 
ATOM 1249 C CB  . MET A 1 215 ? 172.887 150.991 182.538 1.00 86.64  ? 524 MET B CB  1 
ATOM 1250 C CG  . MET A 1 215 ? 171.978 150.873 181.317 1.00 86.64  ? 524 MET B CG  1 
ATOM 1251 S SD  . MET A 1 215 ? 171.065 152.335 180.820 1.00 86.64  ? 524 MET B SD  1 
ATOM 1252 C CE  . MET A 1 215 ? 172.362 153.246 179.988 1.00 86.64  ? 524 MET B CE  1 
ATOM 1253 N N   . GLY A 1 216 ? 171.627 153.378 184.610 1.00 103.23 ? 525 GLY B N   1 
ATOM 1254 C CA  . GLY A 1 216 ? 170.768 154.550 184.679 1.00 103.23 ? 525 GLY B CA  1 
ATOM 1255 C C   . GLY A 1 216 ? 169.493 154.395 185.480 1.00 103.23 ? 525 GLY B C   1 
ATOM 1256 O O   . GLY A 1 216 ? 168.496 155.051 185.167 1.00 103.23 ? 525 GLY B O   1 
ATOM 1257 N N   . CYS A 1 217 ? 169.492 153.567 186.519 1.00 116.52 ? 526 CYS B N   1 
ATOM 1258 C CA  . CYS A 1 217 ? 168.302 153.444 187.344 1.00 116.52 ? 526 CYS B CA  1 
ATOM 1259 C C   . CYS A 1 217 ? 168.474 154.175 188.674 1.00 116.52 ? 526 CYS B C   1 
ATOM 1260 O O   . CYS A 1 217 ? 169.571 154.592 189.054 1.00 116.52 ? 526 CYS B O   1 
ATOM 1261 C CB  . CYS A 1 217 ? 167.948 151.979 187.568 1.00 116.52 ? 526 CYS B CB  1 
ATOM 1262 S SG  . CYS A 1 217 ? 167.252 151.174 186.122 1.00 116.52 ? 526 CYS B SG  1 
ATOM 1263 N N   . SER A 1 218 ? 167.363 154.306 189.400 1.00 122.32 ? 527 SER B N   1 
ATOM 1264 C CA  . SER A 1 218 ? 167.280 155.066 190.642 1.00 122.32 ? 527 SER B CA  1 
ATOM 1265 C C   . SER A 1 218 ? 167.375 154.180 191.879 1.00 122.32 ? 527 SER B C   1 
ATOM 1266 O O   . SER A 1 218 ? 166.632 154.383 192.844 1.00 122.32 ? 527 SER B O   1 
ATOM 1267 C CB  . SER A 1 218 ? 165.985 155.873 190.677 1.00 122.32 ? 527 SER B CB  1 
ATOM 1268 O OG  . SER A 1 218 ? 165.874 156.581 191.898 1.00 122.32 ? 527 SER B OG  1 
ATOM 1269 N N   . VAL A 1 219 ? 168.257 153.192 191.861 1.00 110.25 ? 528 VAL B N   1 
ATOM 1270 C CA  . VAL A 1 219 ? 168.408 152.260 192.970 1.00 110.25 ? 528 VAL B CA  1 
ATOM 1271 C C   . VAL A 1 219 ? 169.558 152.725 193.851 1.00 110.25 ? 528 VAL B C   1 
ATOM 1272 O O   . VAL A 1 219 ? 170.542 153.293 193.362 1.00 110.25 ? 528 VAL B O   1 
ATOM 1273 C CB  . VAL A 1 219 ? 168.651 150.836 192.456 1.00 110.25 ? 528 VAL B CB  1 
ATOM 1274 C CG1 . VAL A 1 219 ? 167.400 150.300 191.809 1.00 110.25 ? 528 VAL B CG1 1 
ATOM 1275 C CG2 . VAL A 1 219 ? 169.786 150.837 191.465 1.00 110.25 ? 528 VAL B CG2 1 
ATOM 1276 N N   . THR A 1 220 ? 169.427 152.500 195.152 1.00 120.90 ? 529 THR B N   1 
ATOM 1277 C CA  . THR A 1 220 ? 170.422 152.940 196.114 1.00 120.90 ? 529 THR B CA  1 
ATOM 1278 C C   . THR A 1 220 ? 171.436 151.824 196.374 1.00 120.90 ? 529 THR B C   1 
ATOM 1279 O O   . THR A 1 220 ? 171.156 150.638 196.194 1.00 120.90 ? 529 THR B O   1 
ATOM 1280 C CB  . THR A 1 220 ? 169.725 153.384 197.406 1.00 120.90 ? 529 THR B CB  1 
ATOM 1281 O OG1 . THR A 1 220 ? 168.811 154.445 197.106 1.00 120.90 ? 529 THR B OG1 1 
ATOM 1282 C CG2 . THR A 1 220 ? 170.720 153.896 198.438 1.00 120.90 ? 529 THR B CG2 1 
ATOM 1283 N N   . SER A 1 221 ? 172.632 152.224 196.818 1.00 142.06 ? 530 SER B N   1 
ATOM 1284 C CA  . SER A 1 221 ? 173.670 151.272 197.198 1.00 142.06 ? 530 SER B CA  1 
ATOM 1285 C C   . SER A 1 221 ? 173.217 150.332 198.305 1.00 142.06 ? 530 SER B C   1 
ATOM 1286 O O   . SER A 1 221 ? 173.804 149.252 198.477 1.00 142.06 ? 530 SER B O   1 
ATOM 1287 C CB  . SER A 1 221 ? 174.919 152.033 197.648 1.00 142.06 ? 530 SER B CB  1 
ATOM 1288 O OG  . SER A 1 221 ? 175.869 151.162 198.234 1.00 142.06 ? 530 SER B OG  1 
ATOM 1289 N N   . LYS A 1 222 ? 172.186 150.719 199.060 1.00 143.17 ? 531 LYS B N   1 
ATOM 1290 C CA  . LYS A 1 222 ? 171.712 149.886 200.157 1.00 143.17 ? 531 LYS B CA  1 
ATOM 1291 C C   . LYS A 1 222 ? 171.181 148.548 199.660 1.00 143.17 ? 531 LYS B C   1 
ATOM 1292 O O   . LYS A 1 222 ? 171.115 147.585 200.431 1.00 143.17 ? 531 LYS B O   1 
ATOM 1293 C CB  . LYS A 1 222 ? 170.645 150.633 200.960 1.00 143.17 ? 531 LYS B CB  1 
ATOM 1294 C CG  . LYS A 1 222 ? 171.124 151.974 201.503 1.00 143.17 ? 531 LYS B CG  1 
ATOM 1295 C CD  . LYS A 1 222 ? 172.437 151.822 202.258 1.00 143.17 ? 531 LYS B CD  1 
ATOM 1296 C CE  . LYS A 1 222 ? 172.234 151.238 203.643 1.00 143.17 ? 531 LYS B CE  1 
ATOM 1297 N NZ  . LYS A 1 222 ? 173.476 150.577 204.139 1.00 143.17 ? 531 LYS B NZ  1 
ATOM 1298 N N   . GLY A 1 223 ? 170.781 148.469 198.392 1.00 143.95 ? 532 GLY B N   1 
ATOM 1299 C CA  . GLY A 1 223 ? 170.450 147.189 197.797 1.00 143.95 ? 532 GLY B CA  1 
ATOM 1300 C C   . GLY A 1 223 ? 171.653 146.503 197.182 1.00 143.95 ? 532 GLY B C   1 
ATOM 1301 O O   . GLY A 1 223 ? 171.727 145.271 197.160 1.00 143.95 ? 532 GLY B O   1 
ATOM 1302 N N   . VAL A 1 224 ? 172.611 147.296 196.692 1.00 148.30 ? 533 VAL B N   1 
ATOM 1303 C CA  . VAL A 1 224 ? 173.862 146.747 196.172 1.00 148.30 ? 533 VAL B CA  1 
ATOM 1304 C C   . VAL A 1 224 ? 174.583 145.963 197.257 1.00 148.30 ? 533 VAL B C   1 
ATOM 1305 O O   . VAL A 1 224 ? 175.348 145.033 196.969 1.00 148.30 ? 533 VAL B O   1 
ATOM 1306 C CB  . VAL A 1 224 ? 174.738 147.883 195.601 1.00 148.30 ? 533 VAL B CB  1 
ATOM 1307 C CG1 . VAL A 1 224 ? 176.174 147.422 195.362 1.00 148.30 ? 533 VAL B CG1 1 
ATOM 1308 C CG2 . VAL A 1 224 ? 174.133 148.415 194.315 1.00 148.30 ? 533 VAL B CG2 1 
ATOM 1309 N N   . ILE A 1 225 ? 174.334 146.308 198.519 1.00 143.68 ? 534 ILE B N   1 
ATOM 1310 C CA  . ILE A 1 225 ? 174.873 145.521 199.623 1.00 143.68 ? 534 ILE B CA  1 
ATOM 1311 C C   . ILE A 1 225 ? 174.487 144.055 199.477 1.00 143.68 ? 534 ILE B C   1 
ATOM 1312 O O   . ILE A 1 225 ? 175.308 143.155 199.689 1.00 143.68 ? 534 ILE B O   1 
ATOM 1313 C CB  . ILE A 1 225 ? 174.382 146.098 200.962 1.00 143.68 ? 534 ILE B CB  1 
ATOM 1314 C CG1 . ILE A 1 225 ? 174.822 147.555 201.102 1.00 143.68 ? 534 ILE B CG1 1 
ATOM 1315 C CG2 . ILE A 1 225 ? 174.875 145.253 202.123 1.00 143.68 ? 534 ILE B CG2 1 
ATOM 1316 C CD1 . ILE A 1 225 ? 176.314 147.739 201.089 1.00 143.68 ? 534 ILE B CD1 1 
ATOM 1317 N N   . HIS A 1 226 ? 173.240 143.793 199.086 1.00 152.42 ? 535 HIS B N   1 
ATOM 1318 C CA  . HIS A 1 226 ? 172.661 142.456 199.155 1.00 152.42 ? 535 HIS B CA  1 
ATOM 1319 C C   . HIS A 1 226 ? 172.970 141.573 197.952 1.00 152.42 ? 535 HIS B C   1 
ATOM 1320 O O   . HIS A 1 226 ? 172.633 140.385 197.984 1.00 152.42 ? 535 HIS B O   1 
ATOM 1321 C CB  . HIS A 1 226 ? 171.142 142.562 199.315 1.00 152.42 ? 535 HIS B CB  1 
ATOM 1322 C CG  . HIS A 1 226 ? 170.707 142.900 200.704 1.00 152.42 ? 535 HIS B CG  1 
ATOM 1323 N ND1 . HIS A 1 226 ? 169.727 143.831 200.972 1.00 152.42 ? 535 HIS B ND1 1 
ATOM 1324 C CD2 . HIS A 1 226 ? 171.111 142.422 201.905 1.00 152.42 ? 535 HIS B CD2 1 
ATOM 1325 C CE1 . HIS A 1 226 ? 169.552 143.919 202.279 1.00 152.42 ? 535 HIS B CE1 1 
ATOM 1326 N NE2 . HIS A 1 226 ? 170.379 143.072 202.868 1.00 152.42 ? 535 HIS B NE2 1 
ATOM 1327 N N   . LEU A 1 227 ? 173.595 142.101 196.900 1.00 157.98 ? 536 LEU B N   1 
ATOM 1328 C CA  . LEU A 1 227 ? 173.877 141.261 195.741 1.00 157.98 ? 536 LEU B CA  1 
ATOM 1329 C C   . LEU A 1 227 ? 174.982 140.253 196.017 1.00 157.98 ? 536 LEU B C   1 
ATOM 1330 O O   . LEU A 1 227 ? 175.220 139.366 195.190 1.00 157.98 ? 536 LEU B O   1 
ATOM 1331 C CB  . LEU A 1 227 ? 174.237 142.116 194.528 1.00 157.98 ? 536 LEU B CB  1 
ATOM 1332 C CG  . LEU A 1 227 ? 173.054 142.525 193.642 1.00 157.98 ? 536 LEU B CG  1 
ATOM 1333 C CD1 . LEU A 1 227 ? 173.554 143.085 192.316 1.00 157.98 ? 536 LEU B CD1 1 
ATOM 1334 C CD2 . LEU A 1 227 ? 172.060 141.382 193.430 1.00 157.98 ? 536 LEU B CD2 1 
ATOM 1335 N N   . THR A 1 228 ? 175.657 140.371 197.154 1.00 154.16 ? 537 THR B N   1 
ATOM 1336 C CA  . THR A 1 228 ? 176.615 139.370 197.589 1.00 154.16 ? 537 THR B CA  1 
ATOM 1337 C C   . THR A 1 228 ? 175.951 138.065 198.008 1.00 154.16 ? 537 THR B C   1 
ATOM 1338 O O   . THR A 1 228 ? 176.658 137.139 198.419 1.00 154.16 ? 537 THR B O   1 
ATOM 1339 C CB  . THR A 1 228 ? 177.427 139.936 198.746 1.00 154.16 ? 537 THR B CB  1 
ATOM 1340 O OG1 . THR A 1 228 ? 178.505 139.051 199.055 1.00 154.16 ? 537 THR B OG1 1 
ATOM 1341 C CG2 . THR A 1 228 ? 176.536 140.104 199.959 1.00 154.16 ? 537 THR B CG2 1 
ATOM 1342 N N   . LYS A 1 229 ? 174.618 137.982 197.945 1.00 145.16 ? 538 LYS B N   1 
ATOM 1343 C CA  . LYS A 1 229 ? 173.913 136.772 198.359 1.00 145.16 ? 538 LYS B CA  1 
ATOM 1344 C C   . LYS A 1 229 ? 174.251 135.587 197.464 1.00 145.16 ? 538 LYS B C   1 
ATOM 1345 O O   . LYS A 1 229 ? 174.947 134.653 197.878 1.00 145.16 ? 538 LYS B O   1 
ATOM 1346 C CB  . LYS A 1 229 ? 172.402 137.011 198.340 1.00 145.16 ? 538 LYS B CB  1 
ATOM 1347 C CG  . LYS A 1 229 ? 171.807 137.494 199.637 1.00 145.16 ? 538 LYS B CG  1 
ATOM 1348 C CD  . LYS A 1 229 ? 170.303 137.282 199.639 1.00 145.16 ? 538 LYS B CD  1 
ATOM 1349 C CE  . LYS A 1 229 ? 169.705 137.653 200.980 1.00 145.16 ? 538 LYS B CE  1 
ATOM 1350 N NZ  . LYS A 1 229 ? 168.261 137.326 201.045 1.00 145.16 ? 538 LYS B NZ  1 
ATOM 1351 N N   . LEU A 1 230 ? 173.769 135.614 196.224 1.00 136.09 ? 539 LEU B N   1 
ATOM 1352 C CA  . LEU A 1 230 ? 173.833 134.435 195.377 1.00 136.09 ? 539 LEU B CA  1 
ATOM 1353 C C   . LEU A 1 230 ? 175.169 134.370 194.649 1.00 136.09 ? 539 LEU B C   1 
ATOM 1354 O O   . LEU A 1 230 ? 175.808 135.385 194.370 1.00 136.09 ? 539 LEU B O   1 
ATOM 1355 C CB  . LEU A 1 230 ? 172.663 134.425 194.390 1.00 136.09 ? 539 LEU B CB  1 
ATOM 1356 C CG  . LEU A 1 230 ? 172.497 135.593 193.416 1.00 136.09 ? 539 LEU B CG  1 
ATOM 1357 C CD1 . LEU A 1 230 ? 173.271 135.359 192.131 1.00 136.09 ? 539 LEU B CD1 1 
ATOM 1358 C CD2 . LEU A 1 230 ? 171.023 135.849 193.127 1.00 136.09 ? 539 LEU B CD2 1 
ATOM 1359 N N   . ARG A 1 231 ? 175.582 133.147 194.331 1.00 112.30 ? 540 ARG B N   1 
ATOM 1360 C CA  . ARG A 1 231 ? 176.887 132.883 193.744 1.00 112.30 ? 540 ARG B CA  1 
ATOM 1361 C C   . ARG A 1 231 ? 176.726 132.378 192.322 1.00 112.30 ? 540 ARG B C   1 
ATOM 1362 O O   . ARG A 1 231 ? 177.627 131.763 191.746 1.00 112.30 ? 540 ARG B O   1 
ATOM 1363 C CB  . ARG A 1 231 ? 177.658 131.883 194.599 1.00 112.30 ? 540 ARG B CB  1 
ATOM 1364 C CG  . ARG A 1 231 ? 178.493 132.543 195.664 1.00 112.30 ? 540 ARG B CG  1 
ATOM 1365 C CD  . ARG A 1 231 ? 178.989 131.548 196.696 1.00 112.30 ? 540 ARG B CD  1 
ATOM 1366 N NE  . ARG A 1 231 ? 178.933 132.099 198.044 1.00 112.30 ? 540 ARG B NE  1 
ATOM 1367 C CZ  . ARG A 1 231 ? 178.344 131.506 199.074 1.00 112.30 ? 540 ARG B CZ  1 
ATOM 1368 N N   . ASN A 1 232 ? 175.580 132.689 191.722 1.00 99.54  ? 541 ASN B N   1 
ATOM 1369 C CA  . ASN A 1 232 ? 175.275 132.259 190.366 1.00 99.54  ? 541 ASN B CA  1 
ATOM 1370 C C   . ASN A 1 232 ? 175.449 133.411 189.391 1.00 99.54  ? 541 ASN B C   1 
ATOM 1371 O O   . ASN A 1 232 ? 175.460 133.185 188.175 1.00 99.54  ? 541 ASN B O   1 
ATOM 1372 C CB  . ASN A 1 232 ? 173.835 131.746 190.294 1.00 99.54  ? 541 ASN B CB  1 
ATOM 1373 C CG  . ASN A 1 232 ? 173.632 130.474 191.079 1.00 99.54  ? 541 ASN B CG  1 
ATOM 1374 O OD1 . ASN A 1 232 ? 174.475 129.582 191.064 1.00 99.54  ? 541 ASN B OD1 1 
ATOM 1375 N ND2 . ASN A 1 232 ? 172.522 130.399 191.801 1.00 99.54  ? 541 ASN B ND2 1 
ATOM 1376 N N   . LEU A 1 233 ? 175.605 134.626 189.896 1.00 99.46  ? 542 LEU B N   1 
ATOM 1377 C CA  . LEU A 1 233 ? 175.618 135.809 189.057 1.00 99.46  ? 542 LEU B CA  1 
ATOM 1378 C C   . LEU A 1 233 ? 176.907 135.895 188.260 1.00 99.46  ? 542 LEU B C   1 
ATOM 1379 O O   . LEU A 1 233 ? 177.993 135.656 188.784 1.00 99.46  ? 542 LEU B O   1 
ATOM 1380 C CB  . LEU A 1 233 ? 175.448 137.050 189.924 1.00 99.46  ? 542 LEU B CB  1 
ATOM 1381 C CG  . LEU A 1 233 ? 175.380 138.356 189.161 1.00 99.46  ? 542 LEU B CG  1 
ATOM 1382 C CD1 . LEU A 1 233 ? 174.170 138.313 188.271 1.00 99.46  ? 542 LEU B CD1 1 
ATOM 1383 C CD2 . LEU A 1 233 ? 175.263 139.489 190.151 1.00 99.46  ? 542 LEU B CD2 1 
ATOM 1384 N N   . SER A 1 234 ? 176.783 136.259 186.992 1.00 74.88  ? 543 SER B N   1 
ATOM 1385 C CA  . SER A 1 234 ? 177.929 136.325 186.102 1.00 74.88  ? 543 SER B CA  1 
ATOM 1386 C C   . SER A 1 234 ? 178.181 137.726 185.573 1.00 74.88  ? 543 SER B C   1 
ATOM 1387 O O   . SER A 1 234 ? 179.340 138.105 185.368 1.00 74.88  ? 543 SER B O   1 
ATOM 1388 C CB  . SER A 1 234 ? 177.729 135.347 184.938 1.00 74.88  ? 543 SER B CB  1 
ATOM 1389 O OG  . SER A 1 234 ? 178.803 135.426 184.025 1.00 74.88  ? 543 SER B OG  1 
ATOM 1390 N N   . SER A 1 235 ? 177.131 138.510 185.350 1.00 70.60  ? 544 SER B N   1 
ATOM 1391 C CA  . SER A 1 235 ? 177.258 139.823 184.738 1.00 70.60  ? 544 SER B CA  1 
ATOM 1392 C C   . SER A 1 235 ? 176.568 140.882 185.586 1.00 70.60  ? 544 SER B C   1 
ATOM 1393 O O   . SER A 1 235 ? 175.458 140.672 186.082 1.00 70.60  ? 544 SER B O   1 
ATOM 1394 C CB  . SER A 1 235 ? 176.662 139.823 183.332 1.00 70.60  ? 544 SER B CB  1 
ATOM 1395 O OG  . SER A 1 235 ? 176.580 141.133 182.807 1.00 70.60  ? 544 SER B OG  1 
ATOM 1396 N N   . LEU A 1 236 ? 177.234 142.024 185.734 1.00 64.33  ? 545 LEU B N   1 
ATOM 1397 C CA  . LEU A 1 236 ? 176.695 143.200 186.402 1.00 64.33  ? 545 LEU B CA  1 
ATOM 1398 C C   . LEU A 1 236 ? 176.596 144.352 185.415 1.00 64.33  ? 545 LEU B C   1 
ATOM 1399 O O   . LEU A 1 236 ? 177.472 144.531 184.569 1.00 64.33  ? 545 LEU B O   1 
ATOM 1400 C CB  . LEU A 1 236 ? 177.580 143.652 187.559 1.00 64.33  ? 545 LEU B CB  1 
ATOM 1401 C CG  . LEU A 1 236 ? 177.485 143.015 188.937 1.00 64.33  ? 545 LEU B CG  1 
ATOM 1402 C CD1 . LEU A 1 236 ? 176.109 143.262 189.520 1.00 64.33  ? 545 LEU B CD1 1 
ATOM 1403 C CD2 . LEU A 1 236 ? 177.816 141.544 188.875 1.00 64.33  ? 545 LEU B CD2 1 
ATOM 1404 N N   . ASP A 1 237 ? 175.541 145.150 185.544 1.00 82.18  ? 546 ASP B N   1 
ATOM 1405 C CA  . ASP A 1 237 ? 175.411 146.391 184.783 1.00 82.18  ? 546 ASP B CA  1 
ATOM 1406 C C   . ASP A 1 237 ? 175.063 147.551 185.695 1.00 82.18  ? 546 ASP B C   1 
ATOM 1407 O O   . ASP A 1 237 ? 174.084 148.265 185.488 1.00 82.18  ? 546 ASP B O   1 
ATOM 1408 C CB  . ASP A 1 237 ? 174.394 146.301 183.657 1.00 82.18  ? 546 ASP B CB  1 
ATOM 1409 C CG  . ASP A 1 237 ? 174.844 145.406 182.537 1.00 82.18  ? 546 ASP B CG  1 
ATOM 1410 O OD1 . ASP A 1 237 ? 176.069 145.300 182.331 1.00 82.18  ? 546 ASP B OD1 1 
ATOM 1411 O OD2 . ASP A 1 237 ? 173.980 144.826 181.849 1.00 82.18  ? 546 ASP B OD2 1 
ATOM 1412 N N   . LEU A 1 238 ? 175.863 147.768 186.732 1.00 83.37  ? 547 LEU B N   1 
ATOM 1413 C CA  . LEU A 1 238 ? 175.645 148.924 187.595 1.00 83.37  ? 547 LEU B CA  1 
ATOM 1414 C C   . LEU A 1 238 ? 176.325 150.137 186.956 1.00 83.37  ? 547 LEU B C   1 
ATOM 1415 O O   . LEU A 1 238 ? 177.369 150.623 187.391 1.00 83.37  ? 547 LEU B O   1 
ATOM 1416 C CB  . LEU A 1 238 ? 176.133 148.635 189.012 1.00 83.37  ? 547 LEU B CB  1 
ATOM 1417 C CG  . LEU A 1 238 ? 177.602 148.538 189.435 1.00 83.37  ? 547 LEU B CG  1 
ATOM 1418 C CD1 . LEU A 1 238 ? 177.687 148.612 190.941 1.00 83.37  ? 547 LEU B CD1 1 
ATOM 1419 C CD2 . LEU A 1 238 ? 178.270 147.288 188.922 1.00 83.37  ? 547 LEU B CD2 1 
ATOM 1420 N N   . ARG A 1 239 ? 175.704 150.642 185.893 1.00 75.69  ? 548 ARG B N   1 
ATOM 1421 C CA  . ARG A 1 239 ? 176.049 151.946 185.345 1.00 75.69  ? 548 ARG B CA  1 
ATOM 1422 C C   . ARG A 1 239 ? 175.121 152.986 185.959 1.00 75.69  ? 548 ARG B C   1 
ATOM 1423 O O   . ARG A 1 239 ? 173.921 152.739 186.109 1.00 75.69  ? 548 ARG B O   1 
ATOM 1424 C CB  . ARG A 1 239 ? 175.928 151.989 183.818 1.00 75.69  ? 548 ARG B CB  1 
ATOM 1425 C CG  . ARG A 1 239 ? 176.599 150.855 183.054 1.00 75.69  ? 548 ARG B CG  1 
ATOM 1426 C CD  . ARG A 1 239 ? 176.522 151.084 181.535 1.00 75.69  ? 548 ARG B CD  1 
ATOM 1427 N NE  . ARG A 1 239 ? 175.977 149.946 180.800 1.00 75.69  ? 548 ARG B NE  1 
ATOM 1428 C CZ  . ARG A 1 239 ? 174.937 150.007 179.979 1.00 75.69  ? 548 ARG B CZ  1 
ATOM 1429 N N   . HIS A 1 240 ? 175.678 154.147 186.304 1.00 77.30  ? 549 HIS B N   1 
ATOM 1430 C CA  . HIS A 1 240 ? 174.933 155.210 186.979 1.00 77.30  ? 549 HIS B CA  1 
ATOM 1431 C C   . HIS A 1 240 ? 174.397 154.752 188.336 1.00 77.30  ? 549 HIS B C   1 
ATOM 1432 O O   . HIS A 1 240 ? 173.199 154.536 188.526 1.00 77.30  ? 549 HIS B O   1 
ATOM 1433 C CB  . HIS A 1 240 ? 173.804 155.735 186.093 1.00 77.30  ? 549 HIS B CB  1 
ATOM 1434 C CG  . HIS A 1 240 ? 174.241 156.799 185.147 1.00 77.30  ? 549 HIS B CG  1 
ATOM 1435 N ND1 . HIS A 1 240 ? 173.673 158.053 185.125 1.00 77.30  ? 549 HIS B ND1 1 
ATOM 1436 C CD2 . HIS A 1 240 ? 175.220 156.811 184.214 1.00 77.30  ? 549 HIS B CD2 1 
ATOM 1437 C CE1 . HIS A 1 240 ? 174.270 158.787 184.204 1.00 77.30  ? 549 HIS B CE1 1 
ATOM 1438 N NE2 . HIS A 1 240 ? 175.212 158.056 183.638 1.00 77.30  ? 549 HIS B NE2 1 
ATOM 1439 N N   . ILE A 1 241 ? 175.315 154.582 189.277 1.00 98.52  ? 550 ILE B N   1 
ATOM 1440 C CA  . ILE A 1 241 ? 174.958 154.215 190.636 1.00 98.52  ? 550 ILE B CA  1 
ATOM 1441 C C   . ILE A 1 241 ? 175.528 155.245 191.609 1.00 98.52  ? 550 ILE B C   1 
ATOM 1442 O O   . ILE A 1 241 ? 176.230 156.185 191.221 1.00 98.52  ? 550 ILE B O   1 
ATOM 1443 C CB  . ILE A 1 241 ? 175.426 152.788 190.975 1.00 98.52  ? 550 ILE B CB  1 
ATOM 1444 C CG1 . ILE A 1 241 ? 174.531 152.193 192.063 1.00 98.52  ? 550 ILE B CG1 1 
ATOM 1445 C CG2 . ILE A 1 241 ? 176.892 152.787 191.381 1.00 98.52  ? 550 ILE B CG2 1 
ATOM 1446 C CD1 . ILE A 1 241 ? 173.087 152.094 191.640 1.00 98.52  ? 550 ILE B CD1 1 
ATOM 1447 N N   . THR A 1 242 ? 175.191 155.074 192.893 1.00 104.41 ? 551 THR B N   1 
ATOM 1448 C CA  . THR A 1 242 ? 175.525 156.041 193.938 1.00 104.41 ? 551 THR B CA  1 
ATOM 1449 C C   . THR A 1 242 ? 176.518 155.436 194.933 1.00 104.41 ? 551 THR B C   1 
ATOM 1450 O O   . THR A 1 242 ? 176.148 154.941 195.997 1.00 104.41 ? 551 THR B O   1 
ATOM 1451 C CB  . THR A 1 242 ? 174.251 156.496 194.636 1.00 104.41 ? 551 THR B CB  1 
ATOM 1452 O OG1 . THR A 1 242 ? 173.236 156.747 193.656 1.00 104.41 ? 551 THR B OG1 1 
ATOM 1453 C CG2 . THR A 1 242 ? 174.508 157.767 195.417 1.00 104.41 ? 551 THR B CG2 1 
ATOM 1454 N N   . GLU A 1 243 ? 177.801 155.496 194.572 1.00 131.97 ? 552 GLU B N   1 
ATOM 1455 C CA  . GLU A 1 243 ? 178.937 155.249 195.472 1.00 131.97 ? 552 GLU B CA  1 
ATOM 1456 C C   . GLU A 1 243 ? 178.824 153.919 196.224 1.00 131.97 ? 552 GLU B C   1 
ATOM 1457 O O   . GLU A 1 243 ? 178.532 153.850 197.418 1.00 131.97 ? 552 GLU B O   1 
ATOM 1458 C CB  . GLU A 1 243 ? 179.157 156.415 196.440 1.00 131.97 ? 552 GLU B CB  1 
ATOM 1459 C CG  . GLU A 1 243 ? 180.286 156.181 197.471 1.00 131.97 ? 552 GLU B CG  1 
ATOM 1460 C CD  . GLU A 1 243 ? 181.520 155.470 196.905 1.00 131.97 ? 552 GLU B CD  1 
ATOM 1461 O OE1 . GLU A 1 243 ? 181.965 155.800 195.788 1.00 131.97 ? 552 GLU B OE1 1 
ATOM 1462 O OE2 . GLU A 1 243 ? 182.041 154.558 197.584 1.00 131.97 ? 552 GLU B OE2 1 
ATOM 1463 N N   . LEU A 1 244 ? 179.021 152.849 195.473 1.00 134.17 ? 553 LEU B N   1 
ATOM 1464 C CA  . LEU A 1 244 ? 179.353 151.584 196.107 1.00 134.17 ? 553 LEU B CA  1 
ATOM 1465 C C   . LEU A 1 244 ? 180.722 151.684 196.773 1.00 134.17 ? 553 LEU B C   1 
ATOM 1466 O O   . LEU A 1 244 ? 181.682 152.185 196.182 1.00 134.17 ? 553 LEU B O   1 
ATOM 1467 C CB  . LEU A 1 244 ? 179.313 150.448 195.085 1.00 134.17 ? 553 LEU B CB  1 
ATOM 1468 C CG  . LEU A 1 244 ? 180.378 150.321 193.998 1.00 134.17 ? 553 LEU B CG  1 
ATOM 1469 C CD1 . LEU A 1 244 ? 180.275 148.963 193.343 1.00 134.17 ? 553 LEU B CD1 1 
ATOM 1470 C CD2 . LEU A 1 244 ? 180.164 151.395 192.952 1.00 134.17 ? 553 LEU B CD2 1 
ATOM 1471 N N   . ASP A 1 245 ? 180.802 151.226 198.014 1.00 143.68 ? 554 ASP B N   1 
ATOM 1472 C CA  . ASP A 1 245 ? 182.036 151.289 198.774 1.00 143.68 ? 554 ASP B CA  1 
ATOM 1473 C C   . ASP A 1 245 ? 183.060 150.299 198.237 1.00 143.68 ? 554 ASP B C   1 
ATOM 1474 O O   . ASP A 1 245 ? 182.742 149.378 197.484 1.00 143.68 ? 554 ASP B O   1 
ATOM 1475 C CB  . ASP A 1 245 ? 181.774 150.992 200.249 1.00 143.68 ? 554 ASP B CB  1 
ATOM 1476 C CG  . ASP A 1 245 ? 182.794 151.630 201.169 1.00 143.68 ? 554 ASP B CG  1 
ATOM 1477 O OD1 . ASP A 1 245 ? 184.003 151.370 200.990 1.00 143.68 ? 554 ASP B OD1 1 
ATOM 1478 O OD2 . ASP A 1 245 ? 182.388 152.377 202.081 1.00 143.68 ? 554 ASP B OD2 1 
ATOM 1479 N N   . ASN A 1 246 ? 184.311 150.502 198.646 1.00 154.02 ? 555 ASN B N   1 
ATOM 1480 C CA  . ASN A 1 246 ? 185.318 149.467 198.454 1.00 154.02 ? 555 ASN B CA  1 
ATOM 1481 C C   . ASN A 1 246 ? 184.932 148.196 199.197 1.00 154.02 ? 555 ASN B C   1 
ATOM 1482 O O   . ASN A 1 246 ? 185.181 147.086 198.719 1.00 154.02 ? 555 ASN B O   1 
ATOM 1483 C CB  . ASN A 1 246 ? 186.683 149.975 198.922 1.00 154.02 ? 555 ASN B CB  1 
ATOM 1484 C CG  . ASN A 1 246 ? 186.789 150.066 200.438 1.00 154.02 ? 555 ASN B CG  1 
ATOM 1485 O OD1 . ASN A 1 246 ? 186.889 149.054 201.134 1.00 154.02 ? 555 ASN B OD1 1 
ATOM 1486 N ND2 . ASN A 1 246 ? 186.756 151.287 200.956 1.00 154.02 ? 555 ASN B ND2 1 
ATOM 1487 N N   . GLU A 1 247 ? 184.339 148.336 200.381 1.00 166.78 ? 556 GLU B N   1 
ATOM 1488 C CA  . GLU A 1 247 ? 183.919 147.153 201.117 1.00 166.78 ? 556 GLU B CA  1 
ATOM 1489 C C   . GLU A 1 247 ? 182.829 146.410 200.356 1.00 166.78 ? 556 GLU B C   1 
ATOM 1490 O O   . GLU A 1 247 ? 182.823 145.175 200.311 1.00 166.78 ? 556 GLU B O   1 
ATOM 1491 C CB  . GLU A 1 247 ? 183.438 147.540 202.514 1.00 166.78 ? 556 GLU B CB  1 
ATOM 1492 C CG  . GLU A 1 247 ? 182.916 146.361 203.311 1.00 166.78 ? 556 GLU B CG  1 
ATOM 1493 C CD  . GLU A 1 247 ? 184.001 145.331 203.566 1.00 166.78 ? 556 GLU B CD  1 
ATOM 1494 O OE1 . GLU A 1 247 ? 185.148 145.743 203.844 1.00 166.78 ? 556 GLU B OE1 1 
ATOM 1495 O OE2 . GLU A 1 247 ? 183.723 144.118 203.474 1.00 166.78 ? 556 GLU B OE2 1 
ATOM 1496 N N   . THR A 1 248 ? 181.903 147.153 199.742 1.00 160.51 ? 557 THR B N   1 
ATOM 1497 C CA  . THR A 1 248 ? 180.867 146.529 198.926 1.00 160.51 ? 557 THR B CA  1 
ATOM 1498 C C   . THR A 1 248 ? 181.478 145.749 197.775 1.00 160.51 ? 557 THR B C   1 
ATOM 1499 O O   . THR A 1 248 ? 181.093 144.598 197.516 1.00 160.51 ? 557 THR B O   1 
ATOM 1500 C CB  . THR A 1 248 ? 179.913 147.589 198.378 1.00 160.51 ? 557 THR B CB  1 
ATOM 1501 O OG1 . THR A 1 248 ? 180.603 148.390 197.410 1.00 160.51 ? 557 THR B OG1 1 
ATOM 1502 C CG2 . THR A 1 248 ? 179.402 148.484 199.487 1.00 160.51 ? 557 THR B CG2 1 
ATOM 1503 N N   . VAL A 1 249 ? 182.437 146.360 197.073 1.00 162.36 ? 558 VAL B N   1 
ATOM 1504 C CA  . VAL A 1 249 ? 183.032 145.687 195.928 1.00 162.36 ? 558 VAL B CA  1 
ATOM 1505 C C   . VAL A 1 249 ? 183.784 144.450 196.388 1.00 162.36 ? 558 VAL B C   1 
ATOM 1506 O O   . VAL A 1 249 ? 183.711 143.393 195.754 1.00 162.36 ? 558 VAL B O   1 
ATOM 1507 C CB  . VAL A 1 249 ? 183.924 146.654 195.117 1.00 162.36 ? 558 VAL B CB  1 
ATOM 1508 C CG1 . VAL A 1 249 ? 183.186 147.921 194.801 1.00 162.36 ? 558 VAL B CG1 1 
ATOM 1509 C CG2 . VAL A 1 249 ? 185.217 146.985 195.821 1.00 162.36 ? 558 VAL B CG2 1 
ATOM 1510 N N   . MET A 1 250 ? 184.467 144.537 197.528 1.00 175.08 ? 559 MET B N   1 
ATOM 1511 C CA  . MET A 1 250 ? 185.190 143.381 198.037 1.00 175.08 ? 559 MET B CA  1 
ATOM 1512 C C   . MET A 1 250 ? 184.251 142.252 198.431 1.00 175.08 ? 559 MET B C   1 
ATOM 1513 O O   . MET A 1 250 ? 184.517 141.085 198.117 1.00 175.08 ? 559 MET B O   1 
ATOM 1514 C CB  . MET A 1 250 ? 186.090 143.815 199.189 1.00 175.08 ? 559 MET B CB  1 
ATOM 1515 C CG  . MET A 1 250 ? 187.168 144.739 198.683 1.00 175.08 ? 559 MET B CG  1 
ATOM 1516 S SD  . MET A 1 250 ? 188.163 143.811 197.496 1.00 175.08 ? 559 MET B SD  1 
ATOM 1517 C CE  . MET A 1 250 ? 187.565 144.393 195.917 1.00 175.08 ? 559 MET B CE  1 
ATOM 1518 N N   . GLU A 1 251 ? 183.144 142.569 199.104 1.00 186.27 ? 560 GLU B N   1 
ATOM 1519 C CA  . GLU A 1 251 ? 182.229 141.505 199.502 1.00 186.27 ? 560 GLU B CA  1 
ATOM 1520 C C   . GLU A 1 251 ? 181.614 140.840 198.284 1.00 186.27 ? 560 GLU B C   1 
ATOM 1521 O O   . GLU A 1 251 ? 181.540 139.606 198.207 1.00 186.27 ? 560 GLU B O   1 
ATOM 1522 C CB  . GLU A 1 251 ? 181.124 142.046 200.406 1.00 186.27 ? 560 GLU B CB  1 
ATOM 1523 C CG  . GLU A 1 251 ? 180.202 140.956 200.915 1.00 186.27 ? 560 GLU B CG  1 
ATOM 1524 C CD  . GLU A 1 251 ? 179.129 141.466 201.849 1.00 186.27 ? 560 GLU B CD  1 
ATOM 1525 O OE1 . GLU A 1 251 ? 179.079 142.687 202.087 1.00 186.27 ? 560 GLU B OE1 1 
ATOM 1526 O OE2 . GLU A 1 251 ? 178.361 140.638 202.380 1.00 186.27 ? 560 GLU B OE2 1 
ATOM 1527 N N   . ILE A 1 252 ? 181.170 141.643 197.316 1.00 156.39 ? 561 ILE B N   1 
ATOM 1528 C CA  . ILE A 1 252 ? 180.477 141.065 196.178 1.00 156.39 ? 561 ILE B CA  1 
ATOM 1529 C C   . ILE A 1 252 ? 181.445 140.293 195.293 1.00 156.39 ? 561 ILE B C   1 
ATOM 1530 O O   . ILE A 1 252 ? 181.058 139.305 194.660 1.00 156.39 ? 561 ILE B O   1 
ATOM 1531 C CB  . ILE A 1 252 ? 179.719 142.157 195.405 1.00 156.39 ? 561 ILE B CB  1 
ATOM 1532 C CG1 . ILE A 1 252 ? 178.714 141.520 194.456 1.00 156.39 ? 561 ILE B CG1 1 
ATOM 1533 C CG2 . ILE A 1 252 ? 180.678 143.047 194.641 1.00 156.39 ? 561 ILE B CG2 1 
ATOM 1534 C CD1 . ILE A 1 252 ? 177.669 142.479 193.982 1.00 156.39 ? 561 ILE B CD1 1 
ATOM 1535 N N   . VAL A 1 253 ? 182.714 140.708 195.236 1.00 163.34 ? 562 VAL B N   1 
ATOM 1536 C CA  . VAL A 1 253 ? 183.683 139.914 194.495 1.00 163.34 ? 562 VAL B CA  1 
ATOM 1537 C C   . VAL A 1 253 ? 184.012 138.618 195.233 1.00 163.34 ? 562 VAL B C   1 
ATOM 1538 O O   . VAL A 1 253 ? 184.059 137.549 194.613 1.00 163.34 ? 562 VAL B O   1 
ATOM 1539 C CB  . VAL A 1 253 ? 184.954 140.734 194.202 1.00 163.34 ? 562 VAL B CB  1 
ATOM 1540 C CG1 . VAL A 1 253 ? 186.012 139.852 193.559 1.00 163.34 ? 562 VAL B CG1 1 
ATOM 1541 C CG2 . VAL A 1 253 ? 184.638 141.906 193.289 1.00 163.34 ? 562 VAL B CG2 1 
ATOM 1542 N N   . LYS A 1 254 ? 184.227 138.669 196.557 1.00 174.41 ? 563 LYS B N   1 
ATOM 1543 C CA  . LYS A 1 254 ? 184.668 137.463 197.255 1.00 174.41 ? 563 LYS B CA  1 
ATOM 1544 C C   . LYS A 1 254 ? 183.565 136.424 197.364 1.00 174.41 ? 563 LYS B C   1 
ATOM 1545 O O   . LYS A 1 254 ? 183.828 135.230 197.180 1.00 174.41 ? 563 LYS B O   1 
ATOM 1546 C CB  . LYS A 1 254 ? 185.208 137.774 198.656 1.00 174.41 ? 563 LYS B CB  1 
ATOM 1547 C CG  . LYS A 1 254 ? 184.215 138.319 199.667 1.00 174.41 ? 563 LYS B CG  1 
ATOM 1548 C CD  . LYS A 1 254 ? 184.899 138.524 201.021 1.00 174.41 ? 563 LYS B CD  1 
ATOM 1549 C CE  . LYS A 1 254 ? 185.866 139.691 201.063 1.00 174.41 ? 563 LYS B CE  1 
ATOM 1550 N NZ  . LYS A 1 254 ? 185.184 140.997 200.907 1.00 174.41 ? 563 LYS B NZ  1 
ATOM 1551 N N   . ARG A 1 255 ? 182.339 136.836 197.677 1.00 162.00 ? 564 ARG B N   1 
ATOM 1552 C CA  . ARG A 1 255 ? 181.267 135.854 197.780 1.00 162.00 ? 564 ARG B CA  1 
ATOM 1553 C C   . ARG A 1 255 ? 180.953 135.272 196.408 1.00 162.00 ? 564 ARG B C   1 
ATOM 1554 O O   . ARG A 1 255 ? 180.980 134.053 196.222 1.00 162.00 ? 564 ARG B O   1 
ATOM 1555 C CB  . ARG A 1 255 ? 180.027 136.489 198.411 1.00 162.00 ? 564 ARG B CB  1 
ATOM 1556 C CG  . ARG A 1 255 ? 180.130 136.604 199.915 1.00 162.00 ? 564 ARG B CG  1 
ATOM 1557 C CD  . ARG A 1 255 ? 179.036 135.832 200.614 1.00 162.00 ? 564 ARG B CD  1 
ATOM 1558 N NE  . ARG A 1 255 ? 178.842 136.323 201.972 1.00 162.00 ? 564 ARG B NE  1 
ATOM 1559 C CZ  . ARG A 1 255 ? 179.506 137.342 202.498 1.00 162.00 ? 564 ARG B CZ  1 
ATOM 1560 N N   . CYS A 1 256 ? 180.733 136.141 195.423 1.00 152.27 ? 565 CYS B N   1 
ATOM 1561 C CA  . CYS A 1 256 ? 180.412 135.725 194.062 1.00 152.27 ? 565 CYS B CA  1 
ATOM 1562 C C   . CYS A 1 256 ? 181.715 135.425 193.321 1.00 152.27 ? 565 CYS B C   1 
ATOM 1563 O O   . CYS A 1 256 ? 182.202 136.202 192.498 1.00 152.27 ? 565 CYS B O   1 
ATOM 1564 C CB  . CYS A 1 256 ? 179.614 136.811 193.359 1.00 152.27 ? 565 CYS B CB  1 
ATOM 1565 S SG  . CYS A 1 256 ? 178.122 137.315 194.236 1.00 152.27 ? 565 CYS B SG  1 
ATOM 1566 N N   . LYS A 1 257 ? 182.298 134.268 193.646 1.00 138.19 ? 566 LYS B N   1 
ATOM 1567 C CA  . LYS A 1 257 ? 183.548 133.876 193.003 1.00 138.19 ? 566 LYS B CA  1 
ATOM 1568 C C   . LYS A 1 257 ? 183.355 133.680 191.509 1.00 138.19 ? 566 LYS B C   1 
ATOM 1569 O O   . LYS A 1 257 ? 184.271 133.933 190.720 1.00 138.19 ? 566 LYS B O   1 
ATOM 1570 C CB  . LYS A 1 257 ? 184.092 132.586 193.620 1.00 138.19 ? 566 LYS B CB  1 
ATOM 1571 C CG  . LYS A 1 257 ? 183.215 131.366 193.358 1.00 138.19 ? 566 LYS B CG  1 
ATOM 1572 C CD  . LYS A 1 257 ? 183.739 130.116 194.033 1.00 138.19 ? 566 LYS B CD  1 
ATOM 1573 C CE  . LYS A 1 257 ? 182.875 128.917 193.677 1.00 138.19 ? 566 LYS B CE  1 
ATOM 1574 N NZ  . LYS A 1 257 ? 181.488 129.050 194.197 1.00 138.19 ? 566 LYS B NZ  1 
ATOM 1575 N N   . ASN A 1 258 ? 182.171 133.235 191.109 1.00 119.34 ? 567 ASN B N   1 
ATOM 1576 C CA  . ASN A 1 258 ? 181.882 132.898 189.723 1.00 119.34 ? 567 ASN B CA  1 
ATOM 1577 C C   . ASN A 1 258 ? 181.266 134.124 189.070 1.00 119.34 ? 567 ASN B C   1 
ATOM 1578 O O   . ASN A 1 258 ? 180.053 134.222 188.914 1.00 119.34 ? 567 ASN B O   1 
ATOM 1579 C CB  . ASN A 1 258 ? 180.951 131.695 189.664 1.00 119.34 ? 567 ASN B CB  1 
ATOM 1580 C CG  . ASN A 1 258 ? 180.755 131.179 188.264 1.00 119.34 ? 567 ASN B CG  1 
ATOM 1581 O OD1 . ASN A 1 258 ? 181.535 131.481 187.365 1.00 119.34 ? 567 ASN B OD1 1 
ATOM 1582 N ND2 . ASN A 1 258 ? 179.709 130.385 188.069 1.00 119.34 ? 567 ASN B ND2 1 
ATOM 1583 N N   . LEU A 1 259 ? 182.117 135.071 188.674 1.00 95.85  ? 568 LEU B N   1 
ATOM 1584 C CA  . LEU A 1 259 ? 181.665 136.330 188.094 1.00 95.85  ? 568 LEU B CA  1 
ATOM 1585 C C   . LEU A 1 259 ? 182.491 136.622 186.852 1.00 95.85  ? 568 LEU B C   1 
ATOM 1586 O O   . LEU A 1 259 ? 183.715 136.470 186.877 1.00 95.85  ? 568 LEU B O   1 
ATOM 1587 C CB  . LEU A 1 259 ? 181.802 137.472 189.104 1.00 95.85  ? 568 LEU B CB  1 
ATOM 1588 C CG  . LEU A 1 259 ? 180.976 138.726 188.837 1.00 95.85  ? 568 LEU B CG  1 
ATOM 1589 C CD1 . LEU A 1 259 ? 179.521 138.350 188.714 1.00 95.85  ? 568 LEU B CD1 1 
ATOM 1590 C CD2 . LEU A 1 259 ? 181.164 139.740 189.946 1.00 95.85  ? 568 LEU B CD2 1 
ATOM 1591 N N   . SER A 1 260 ? 181.833 137.051 185.776 1.00 79.30  ? 569 SER B N   1 
ATOM 1592 C CA  . SER A 1 260 ? 182.486 137.165 184.477 1.00 79.30  ? 569 SER B CA  1 
ATOM 1593 C C   . SER A 1 260 ? 182.687 138.609 184.030 1.00 79.30  ? 569 SER B C   1 
ATOM 1594 O O   . SER A 1 260 ? 183.789 138.980 183.621 1.00 79.30  ? 569 SER B O   1 
ATOM 1595 C CB  . SER A 1 260 ? 181.684 136.391 183.427 1.00 79.30  ? 569 SER B CB  1 
ATOM 1596 O OG  . SER A 1 260 ? 182.349 136.395 182.178 1.00 79.30  ? 569 SER B OG  1 
ATOM 1597 N N   . SER A 1 261 ? 181.631 139.420 184.064 1.00 73.14  ? 570 SER B N   1 
ATOM 1598 C CA  . SER A 1 261 ? 181.660 140.762 183.500 1.00 73.14  ? 570 SER B CA  1 
ATOM 1599 C C   . SER A 1 261 ? 181.059 141.758 184.480 1.00 73.14  ? 570 SER B C   1 
ATOM 1600 O O   . SER A 1 261 ? 179.962 141.537 185.003 1.00 73.14  ? 570 SER B O   1 
ATOM 1601 C CB  . SER A 1 261 ? 180.882 140.811 182.191 1.00 73.14  ? 570 SER B CB  1 
ATOM 1602 O OG  . SER A 1 261 ? 179.510 141.080 182.439 1.00 73.14  ? 570 SER B OG  1 
ATOM 1603 N N   . LEU A 1 262 ? 181.761 142.868 184.693 1.00 74.14  ? 571 LEU B N   1 
ATOM 1604 C CA  . LEU A 1 262 ? 181.355 143.904 185.634 1.00 74.14  ? 571 LEU B CA  1 
ATOM 1605 C C   . LEU A 1 262 ? 181.322 145.223 184.881 1.00 74.14  ? 571 LEU B C   1 
ATOM 1606 O O   . LEU A 1 262 ? 182.279 145.557 184.174 1.00 74.14  ? 571 LEU B O   1 
ATOM 1607 C CB  . LEU A 1 262 ? 182.330 143.973 186.808 1.00 74.14  ? 571 LEU B CB  1 
ATOM 1608 C CG  . LEU A 1 262 ? 182.081 144.921 187.977 1.00 74.14  ? 571 LEU B CG  1 
ATOM 1609 C CD1 . LEU A 1 262 ? 180.714 144.696 188.580 1.00 74.14  ? 571 LEU B CD1 1 
ATOM 1610 C CD2 . LEU A 1 262 ? 183.171 144.757 189.018 1.00 74.14  ? 571 LEU B CD2 1 
ATOM 1611 N N   . ASN A 1 263 ? 180.230 145.972 185.028 1.00 79.21  ? 572 ASN B N   1 
ATOM 1612 C CA  . ASN A 1 263 ? 180.012 147.114 184.147 1.00 79.21  ? 572 ASN B CA  1 
ATOM 1613 C C   . ASN A 1 263 ? 180.504 148.434 184.741 1.00 79.21  ? 572 ASN B C   1 
ATOM 1614 O O   . ASN A 1 263 ? 181.433 149.043 184.206 1.00 79.21  ? 572 ASN B O   1 
ATOM 1615 C CB  . ASN A 1 263 ? 178.528 147.203 183.807 1.00 79.21  ? 572 ASN B CB  1 
ATOM 1616 C CG  . ASN A 1 263 ? 178.281 147.788 182.453 1.00 79.21  ? 572 ASN B CG  1 
ATOM 1617 O OD1 . ASN A 1 263 ? 177.167 147.739 181.940 1.00 79.21  ? 572 ASN B OD1 1 
ATOM 1618 N ND2 . ASN A 1 263 ? 179.310 148.386 181.876 1.00 79.21  ? 572 ASN B ND2 1 
ATOM 1619 N N   . LEU A 1 264 ? 179.902 148.871 185.850 1.00 84.06  ? 573 LEU B N   1 
ATOM 1620 C CA  . LEU A 1 264 ? 180.225 150.119 186.546 1.00 84.06  ? 573 LEU B CA  1 
ATOM 1621 C C   . LEU A 1 264 ? 180.549 151.298 185.630 1.00 84.06  ? 573 LEU B C   1 
ATOM 1622 O O   . LEU A 1 264 ? 181.457 152.078 185.926 1.00 84.06  ? 573 LEU B O   1 
ATOM 1623 C CB  . LEU A 1 264 ? 181.385 149.912 187.531 1.00 84.06  ? 573 LEU B CB  1 
ATOM 1624 C CG  . LEU A 1 264 ? 182.745 149.306 187.164 1.00 84.06  ? 573 LEU B CG  1 
ATOM 1625 C CD1 . LEU A 1 264 ? 183.744 150.322 186.626 1.00 84.06  ? 573 LEU B CD1 1 
ATOM 1626 C CD2 . LEU A 1 264 ? 183.328 148.611 188.385 1.00 84.06  ? 573 LEU B CD2 1 
ATOM 1627 N N   . CYS A 1 265 ? 179.804 151.475 184.545 1.00 72.49  ? 574 CYS B N   1 
ATOM 1628 C CA  . CYS A 1 265 ? 180.128 152.565 183.638 1.00 72.49  ? 574 CYS B CA  1 
ATOM 1629 C C   . CYS A 1 265 ? 179.495 153.875 184.099 1.00 72.49  ? 574 CYS B C   1 
ATOM 1630 O O   . CYS A 1 265 ? 178.432 153.900 184.724 1.00 72.49  ? 574 CYS B O   1 
ATOM 1631 C CB  . CYS A 1 265 ? 179.675 152.234 182.221 1.00 72.49  ? 574 CYS B CB  1 
ATOM 1632 S SG  . CYS A 1 265 ? 179.943 153.535 181.012 1.00 72.49  ? 574 CYS B SG  1 
ATOM 1633 N N   . LEU A 1 266 ? 180.171 154.977 183.765 1.00 79.51  ? 575 LEU B N   1 
ATOM 1634 C CA  . LEU A 1 266 ? 179.765 156.327 184.156 1.00 79.51  ? 575 LEU B CA  1 
ATOM 1635 C C   . LEU A 1 266 ? 179.568 156.462 185.655 1.00 79.51  ? 575 LEU B C   1 
ATOM 1636 O O   . LEU A 1 266 ? 178.524 156.937 186.109 1.00 79.51  ? 575 LEU B O   1 
ATOM 1637 C CB  . LEU A 1 266 ? 178.500 156.780 183.423 1.00 79.51  ? 575 LEU B CB  1 
ATOM 1638 C CG  . LEU A 1 266 ? 178.719 157.198 181.973 1.00 79.51  ? 575 LEU B CG  1 
ATOM 1639 C CD1 . LEU A 1 266 ? 177.426 157.678 181.330 1.00 79.51  ? 575 LEU B CD1 1 
ATOM 1640 C CD2 . LEU A 1 266 ? 179.777 158.277 181.924 1.00 79.51  ? 575 LEU B CD2 1 
ATOM 1641 N N   . ASN A 1 267 ? 180.543 156.027 186.441 1.00 96.92  ? 576 ASN B N   1 
ATOM 1642 C CA  . ASN A 1 267 ? 180.541 156.261 187.875 1.00 96.92  ? 576 ASN B CA  1 
ATOM 1643 C C   . ASN A 1 267 ? 181.727 157.145 188.234 1.00 96.92  ? 576 ASN B C   1 
ATOM 1644 O O   . ASN A 1 267 ? 182.877 156.771 187.991 1.00 96.92  ? 576 ASN B O   1 
ATOM 1645 C CB  . ASN A 1 267 ? 180.601 154.945 188.644 1.00 96.92  ? 576 ASN B CB  1 
ATOM 1646 C CG  . ASN A 1 267 ? 180.166 155.100 190.075 1.00 96.92  ? 576 ASN B CG  1 
ATOM 1647 O OD1 . ASN A 1 267 ? 179.900 156.209 190.530 1.00 96.92  ? 576 ASN B OD1 1 
ATOM 1648 N ND2 . ASN A 1 267 ? 180.075 153.990 190.793 1.00 96.92  ? 576 ASN B ND2 1 
ATOM 1649 N N   . TRP A 1 268 ? 181.441 158.313 188.810 1.00 107.83 ? 577 TRP B N   1 
ATOM 1650 C CA  . TRP A 1 268 ? 182.460 159.293 189.174 1.00 107.83 ? 577 TRP B CA  1 
ATOM 1651 C C   . TRP A 1 268 ? 183.126 158.978 190.500 1.00 107.83 ? 577 TRP B C   1 
ATOM 1652 O O   . TRP A 1 268 ? 184.356 159.025 190.616 1.00 107.83 ? 577 TRP B O   1 
ATOM 1653 C CB  . TRP A 1 268 ? 181.832 160.685 189.275 1.00 107.83 ? 577 TRP B CB  1 
ATOM 1654 C CG  . TRP A 1 268 ? 181.270 161.203 188.010 1.00 107.83 ? 577 TRP B CG  1 
ATOM 1655 C CD1 . TRP A 1 268 ? 181.966 161.741 186.978 1.00 107.83 ? 577 TRP B CD1 1 
ATOM 1656 C CD2 . TRP A 1 268 ? 179.887 161.194 187.632 1.00 107.83 ? 577 TRP B CD2 1 
ATOM 1657 N NE1 . TRP A 1 268 ? 181.121 162.103 185.969 1.00 107.83 ? 577 TRP B NE1 1 
ATOM 1658 C CE2 . TRP A 1 268 ? 179.836 161.784 186.315 1.00 107.83 ? 577 TRP B CE2 1 
ATOM 1659 C CE3 . TRP A 1 268 ? 178.712 160.739 188.303 1.00 107.83 ? 577 TRP B CE3 1 
ATOM 1660 C CZ2 . TRP A 1 268 ? 178.665 161.976 185.574 1.00 107.83 ? 577 TRP B CZ2 1 
ATOM 1661 C CZ3 . TRP A 1 268 ? 177.429 160.823 187.769 1.00 107.83 ? 577 TRP B CZ3 1 
ATOM 1662 N N   . ILE A 1 269 ? 182.315 158.642 191.500 1.00 126.23 ? 578 ILE B N   1 
ATOM 1663 C CA  . ILE A 1 269 ? 182.738 158.636 192.895 1.00 126.23 ? 578 ILE B CA  1 
ATOM 1664 C C   . ILE A 1 269 ? 183.688 157.505 193.255 1.00 126.23 ? 578 ILE B C   1 
ATOM 1665 O O   . ILE A 1 269 ? 184.342 157.574 194.302 1.00 126.23 ? 578 ILE B O   1 
ATOM 1666 C CB  . ILE A 1 269 ? 181.439 158.622 193.720 1.00 126.23 ? 578 ILE B CB  1 
ATOM 1667 C CG1 . ILE A 1 269 ? 181.705 158.917 195.200 1.00 126.23 ? 578 ILE B CG1 1 
ATOM 1668 C CG2 . ILE A 1 269 ? 180.670 157.355 193.442 1.00 126.23 ? 578 ILE B CG2 1 
ATOM 1669 C CD1 . ILE A 1 269 ? 182.215 160.318 195.461 1.00 126.23 ? 578 ILE B CD1 1 
ATOM 1670 N N   . ILE A 1 270 ? 183.797 156.470 192.423 1.00 115.87 ? 579 ILE B N   1 
ATOM 1671 C CA  . ILE A 1 270 ? 184.722 155.389 192.736 1.00 115.87 ? 579 ILE B CA  1 
ATOM 1672 C C   . ILE A 1 270 ? 186.152 155.868 192.566 1.00 115.87 ? 579 ILE B C   1 
ATOM 1673 O O   . ILE A 1 270 ? 186.532 156.397 191.514 1.00 115.87 ? 579 ILE B O   1 
ATOM 1674 C CB  . ILE A 1 270 ? 184.428 154.161 191.866 1.00 115.87 ? 579 ILE B CB  1 
ATOM 1675 C CG1 . ILE A 1 270 ? 182.986 153.720 192.087 1.00 115.87 ? 579 ILE B CG1 1 
ATOM 1676 C CG2 . ILE A 1 270 ? 185.399 153.045 192.181 1.00 115.87 ? 579 ILE B CG2 1 
ATOM 1677 C CD1 . ILE A 1 270 ? 182.608 153.690 193.544 1.00 115.87 ? 579 ILE B CD1 1 
ATOM 1678 N N   . ASN A 1 271 ? 186.957 155.666 193.603 1.00 137.37 ? 580 ASN B N   1 
ATOM 1679 C CA  . ASN A 1 271 ? 188.348 156.083 193.603 1.00 137.37 ? 580 ASN B CA  1 
ATOM 1680 C C   . ASN A 1 271 ? 189.171 155.076 192.807 1.00 137.37 ? 580 ASN B C   1 
ATOM 1681 O O   . ASN A 1 271 ? 188.644 154.107 192.255 1.00 137.37 ? 580 ASN B O   1 
ATOM 1682 C CB  . ASN A 1 271 ? 188.859 156.221 195.037 1.00 137.37 ? 580 ASN B CB  1 
ATOM 1683 C CG  . ASN A 1 271 ? 188.740 154.927 195.829 1.00 137.37 ? 580 ASN B CG  1 
ATOM 1684 O OD1 . ASN A 1 271 ? 188.358 153.883 195.298 1.00 137.37 ? 580 ASN B OD1 1 
ATOM 1685 N ND2 . ASN A 1 271 ? 189.068 154.995 197.114 1.00 137.37 ? 580 ASN B ND2 1 
ATOM 1686 N N   . ASP A 1 272 ? 190.483 155.289 192.749 1.00 158.24 ? 581 ASP B N   1 
ATOM 1687 C CA  . ASP A 1 272 ? 191.335 154.295 192.115 1.00 158.24 ? 581 ASP B CA  1 
ATOM 1688 C C   . ASP A 1 272 ? 191.437 153.034 192.956 1.00 158.24 ? 581 ASP B C   1 
ATOM 1689 O O   . ASP A 1 272 ? 191.743 151.969 192.419 1.00 158.24 ? 581 ASP B O   1 
ATOM 1690 C CB  . ASP A 1 272 ? 192.732 154.864 191.862 1.00 158.24 ? 581 ASP B CB  1 
ATOM 1691 C CG  . ASP A 1 272 ? 193.418 154.212 190.674 1.00 158.24 ? 581 ASP B CG  1 
ATOM 1692 O OD1 . ASP A 1 272 ? 192.736 153.484 189.925 1.00 158.24 ? 581 ASP B OD1 1 
ATOM 1693 O OD2 . ASP A 1 272 ? 194.636 154.416 190.494 1.00 158.24 ? 581 ASP B OD2 1 
ATOM 1694 N N   . ARG A 1 273 ? 191.175 153.131 194.261 1.00 149.97 ? 582 ARG B N   1 
ATOM 1695 C CA  . ARG A 1 273 ? 191.461 152.020 195.163 1.00 149.97 ? 582 ARG B CA  1 
ATOM 1696 C C   . ARG A 1 273 ? 190.511 150.846 194.960 1.00 149.97 ? 582 ARG B C   1 
ATOM 1697 O O   . ARG A 1 273 ? 190.920 149.688 195.106 1.00 149.97 ? 582 ARG B O   1 
ATOM 1698 C CB  . ARG A 1 273 ? 191.413 152.502 196.611 1.00 149.97 ? 582 ARG B CB  1 
ATOM 1699 C CG  . ARG A 1 273 ? 192.098 151.573 197.599 1.00 149.97 ? 582 ARG B CG  1 
ATOM 1700 C CD  . ARG A 1 273 ? 193.603 151.572 197.383 1.00 149.97 ? 582 ARG B CD  1 
ATOM 1701 N NE  . ARG A 1 273 ? 194.338 151.671 198.637 1.00 149.97 ? 582 ARG B NE  1 
ATOM 1702 C CZ  . ARG A 1 273 ? 193.866 152.243 199.736 1.00 149.97 ? 582 ARG B CZ  1 
ATOM 1703 N N   . CYS A 1 274 ? 189.245 151.114 194.634 1.00 158.25 ? 583 CYS B N   1 
ATOM 1704 C CA  . CYS A 1 274 ? 188.308 150.020 194.404 1.00 158.25 ? 583 CYS B CA  1 
ATOM 1705 C C   . CYS A 1 274 ? 188.766 149.156 193.237 1.00 158.25 ? 583 CYS B C   1 
ATOM 1706 O O   . CYS A 1 274 ? 188.725 147.924 193.304 1.00 158.25 ? 583 CYS B O   1 
ATOM 1707 C CB  . CYS A 1 274 ? 186.907 150.571 194.155 1.00 158.25 ? 583 CYS B CB  1 
ATOM 1708 S SG  . CYS A 1 274 ? 186.137 151.313 195.608 1.00 158.25 ? 583 CYS B SG  1 
ATOM 1709 N N   . VAL A 1 275 ? 189.222 149.793 192.157 1.00 175.24 ? 584 VAL B N   1 
ATOM 1710 C CA  . VAL A 1 275 ? 189.816 149.070 191.039 1.00 175.24 ? 584 VAL B CA  1 
ATOM 1711 C C   . VAL A 1 275 ? 191.139 148.439 191.453 1.00 175.24 ? 584 VAL B C   1 
ATOM 1712 O O   . VAL A 1 275 ? 191.471 147.328 191.018 1.00 175.24 ? 584 VAL B O   1 
ATOM 1713 C CB  . VAL A 1 275 ? 189.994 150.025 189.847 1.00 175.24 ? 584 VAL B CB  1 
ATOM 1714 C CG1 . VAL A 1 275 ? 190.821 149.382 188.746 1.00 175.24 ? 584 VAL B CG1 1 
ATOM 1715 C CG2 . VAL A 1 275 ? 188.644 150.469 189.336 1.00 175.24 ? 584 VAL B CG2 1 
ATOM 1716 N N   . GLU A 1 276 ? 191.909 149.133 192.295 1.00 189.65 ? 585 GLU B N   1 
ATOM 1717 C CA  . GLU A 1 276 ? 193.159 148.594 192.816 1.00 189.65 ? 585 GLU B CA  1 
ATOM 1718 C C   . GLU A 1 276 ? 192.925 147.234 193.454 1.00 189.65 ? 585 GLU B C   1 
ATOM 1719 O O   . GLU A 1 276 ? 193.774 146.339 193.374 1.00 189.65 ? 585 GLU B O   1 
ATOM 1720 C CB  . GLU A 1 276 ? 193.743 149.562 193.851 1.00 189.65 ? 585 GLU B CB  1 
ATOM 1721 C CG  . GLU A 1 276 ? 194.455 150.800 193.300 1.00 189.65 ? 585 GLU B CG  1 
ATOM 1722 C CD  . GLU A 1 276 ? 195.944 150.624 193.105 1.00 189.65 ? 585 GLU B CD  1 
ATOM 1723 O OE1 . GLU A 1 276 ? 196.536 149.747 193.765 1.00 189.65 ? 585 GLU B OE1 1 
ATOM 1724 O OE2 . GLU A 1 276 ? 196.526 151.382 192.300 1.00 189.65 ? 585 GLU B OE2 1 
ATOM 1725 N N   . VAL A 1 277 ? 191.771 147.071 194.096 1.00 178.56 ? 586 VAL B N   1 
ATOM 1726 C CA  . VAL A 1 277 ? 191.529 145.912 194.943 1.00 178.56 ? 586 VAL B CA  1 
ATOM 1727 C C   . VAL A 1 277 ? 190.532 144.892 194.372 1.00 178.56 ? 586 VAL B C   1 
ATOM 1728 O O   . VAL A 1 277 ? 190.442 143.777 194.906 1.00 178.56 ? 586 VAL B O   1 
ATOM 1729 C CB  . VAL A 1 277 ? 191.098 146.401 196.344 1.00 178.56 ? 586 VAL B CB  1 
ATOM 1730 C CG1 . VAL A 1 277 ? 189.687 146.965 196.327 1.00 178.56 ? 586 VAL B CG1 1 
ATOM 1731 C CG2 . VAL A 1 277 ? 191.280 145.314 197.397 1.00 178.56 ? 586 VAL B CG2 1 
ATOM 1732 N N   . ILE A 1 278 ? 189.802 145.223 193.298 1.00 151.65 ? 587 ILE B N   1 
ATOM 1733 C CA  . ILE A 1 278 ? 188.991 144.191 192.640 1.00 151.65 ? 587 ILE B CA  1 
ATOM 1734 C C   . ILE A 1 278 ? 189.869 143.042 192.173 1.00 151.65 ? 587 ILE B C   1 
ATOM 1735 O O   . ILE A 1 278 ? 189.527 141.866 192.343 1.00 151.65 ? 587 ILE B O   1 
ATOM 1736 C CB  . ILE A 1 278 ? 188.184 144.762 191.456 1.00 151.65 ? 587 ILE B CB  1 
ATOM 1737 C CG1 . ILE A 1 278 ? 187.197 145.836 191.893 1.00 151.65 ? 587 ILE B CG1 1 
ATOM 1738 C CG2 . ILE A 1 278 ? 187.409 143.653 190.777 1.00 151.65 ? 587 ILE B CG2 1 
ATOM 1739 C CD1 . ILE A 1 278 ? 186.174 145.319 192.835 1.00 151.65 ? 587 ILE B CD1 1 
ATOM 1740 N N   . ALA A 1 279 ? 191.014 143.365 191.580 1.00 153.92 ? 588 ALA B N   1 
ATOM 1741 C CA  . ALA A 1 279 ? 191.827 142.373 190.895 1.00 153.92 ? 588 ALA B CA  1 
ATOM 1742 C C   . ALA A 1 279 ? 192.506 141.388 191.832 1.00 153.92 ? 588 ALA B C   1 
ATOM 1743 O O   . ALA A 1 279 ? 192.865 140.294 191.385 1.00 153.92 ? 588 ALA B O   1 
ATOM 1744 C CB  . ALA A 1 279 ? 192.884 143.073 190.044 1.00 153.92 ? 588 ALA B CB  1 
ATOM 1745 N N   . LYS A 1 280 ? 192.697 141.732 193.108 1.00 166.99 ? 589 LYS B N   1 
ATOM 1746 C CA  . LYS A 1 280 ? 193.426 140.823 193.983 1.00 166.99 ? 589 LYS B CA  1 
ATOM 1747 C C   . LYS A 1 280 ? 192.664 139.528 194.202 1.00 166.99 ? 589 LYS B C   1 
ATOM 1748 O O   . LYS A 1 280 ? 193.280 138.503 194.509 1.00 166.99 ? 589 LYS B O   1 
ATOM 1749 C CB  . LYS A 1 280 ? 193.724 141.486 195.331 1.00 166.99 ? 589 LYS B CB  1 
ATOM 1750 C CG  . LYS A 1 280 ? 192.513 141.803 196.205 1.00 166.99 ? 589 LYS B CG  1 
ATOM 1751 C CD  . LYS A 1 280 ? 192.231 140.672 197.196 1.00 166.99 ? 589 LYS B CD  1 
ATOM 1752 C CE  . LYS A 1 280 ? 191.100 141.009 198.151 1.00 166.99 ? 589 LYS B CE  1 
ATOM 1753 N NZ  . LYS A 1 280 ? 190.838 139.884 199.092 1.00 166.99 ? 589 LYS B NZ  1 
ATOM 1754 N N   . GLU A 1 281 ? 191.344 139.551 194.038 1.00 156.55 ? 590 GLU B N   1 
ATOM 1755 C CA  . GLU A 1 281 ? 190.528 138.373 194.257 1.00 156.55 ? 590 GLU B CA  1 
ATOM 1756 C C   . GLU A 1 281 ? 189.638 138.015 193.081 1.00 156.55 ? 590 GLU B C   1 
ATOM 1757 O O   . GLU A 1 281 ? 189.098 136.905 193.064 1.00 156.55 ? 590 GLU B O   1 
ATOM 1758 C CB  . GLU A 1 281 ? 189.643 138.557 195.494 1.00 156.55 ? 590 GLU B CB  1 
ATOM 1759 C CG  . GLU A 1 281 ? 188.900 139.870 195.515 1.00 156.55 ? 590 GLU B CG  1 
ATOM 1760 C CD  . GLU A 1 281 ? 187.869 139.891 196.604 1.00 156.55 ? 590 GLU B CD  1 
ATOM 1761 O OE1 . GLU A 1 281 ? 187.389 138.801 196.940 1.00 156.55 ? 590 GLU B OE1 1 
ATOM 1762 O OE2 . GLU A 1 281 ? 187.514 140.974 197.102 1.00 156.55 ? 590 GLU B OE2 1 
ATOM 1763 N N   . GLY A 1 282 ? 189.454 138.907 192.112 1.00 158.21 ? 591 GLY B N   1 
ATOM 1764 C CA  . GLY A 1 282 ? 188.721 138.550 190.916 1.00 158.21 ? 591 GLY B CA  1 
ATOM 1765 C C   . GLY A 1 282 ? 189.542 137.646 190.023 1.00 158.21 ? 591 GLY B C   1 
ATOM 1766 O O   . GLY A 1 282 ? 190.509 138.094 189.399 1.00 158.21 ? 591 GLY B O   1 
ATOM 1767 N N   . GLN A 1 283 ? 189.170 136.368 189.954 1.00 133.38 ? 592 GLN B N   1 
ATOM 1768 C CA  . GLN A 1 283 ? 189.975 135.377 189.245 1.00 133.38 ? 592 GLN B CA  1 
ATOM 1769 C C   . GLN A 1 283 ? 189.439 135.097 187.844 1.00 133.38 ? 592 GLN B C   1 
ATOM 1770 O O   . GLN A 1 283 ? 190.171 135.215 186.857 1.00 133.38 ? 592 GLN B O   1 
ATOM 1771 C CB  . GLN A 1 283 ? 190.067 134.087 190.074 1.00 133.38 ? 592 GLN B CB  1 
ATOM 1772 C CG  . GLN A 1 283 ? 188.742 133.432 190.452 1.00 133.38 ? 592 GLN B CG  1 
ATOM 1773 C CD  . GLN A 1 283 ? 188.060 134.117 191.613 1.00 133.38 ? 592 GLN B CD  1 
ATOM 1774 O OE1 . GLN A 1 283 ? 187.675 135.282 191.521 1.00 133.38 ? 592 GLN B OE1 1 
ATOM 1775 N NE2 . GLN A 1 283 ? 187.924 133.403 192.723 1.00 133.38 ? 592 GLN B NE2 1 
ATOM 1776 N N   . ASN A 1 284 ? 188.164 134.746 187.737 1.00 117.04 ? 593 ASN B N   1 
ATOM 1777 C CA  . ASN A 1 284 ? 187.567 134.403 186.460 1.00 117.04 ? 593 ASN B CA  1 
ATOM 1778 C C   . ASN A 1 284 ? 186.975 135.616 185.773 1.00 117.04 ? 593 ASN B C   1 
ATOM 1779 O O   . ASN A 1 284 ? 186.406 135.488 184.688 1.00 117.04 ? 593 ASN B O   1 
ATOM 1780 C CB  . ASN A 1 284 ? 186.486 133.352 186.668 1.00 117.04 ? 593 ASN B CB  1 
ATOM 1781 C CG  . ASN A 1 284 ? 185.602 133.683 187.838 1.00 117.04 ? 593 ASN B CG  1 
ATOM 1782 O OD1 . ASN A 1 284 ? 185.812 134.689 188.515 1.00 117.04 ? 593 ASN B OD1 1 
ATOM 1783 N ND2 . ASN A 1 284 ? 184.629 132.829 188.109 1.00 117.04 ? 593 ASN B ND2 1 
ATOM 1784 N N   . LEU A 1 285 ? 187.089 136.783 186.390 1.00 109.93 ? 594 LEU B N   1 
ATOM 1785 C CA  . LEU A 1 285 ? 186.608 138.006 185.777 1.00 109.93 ? 594 LEU B CA  1 
ATOM 1786 C C   . LEU A 1 285 ? 187.403 138.258 184.506 1.00 109.93 ? 594 LEU B C   1 
ATOM 1787 O O   . LEU A 1 285 ? 188.634 138.185 184.509 1.00 109.93 ? 594 LEU B O   1 
ATOM 1788 C CB  . LEU A 1 285 ? 186.771 139.162 186.760 1.00 109.93 ? 594 LEU B CB  1 
ATOM 1789 C CG  . LEU A 1 285 ? 186.265 140.546 186.393 1.00 109.93 ? 594 LEU B CG  1 
ATOM 1790 C CD1 . LEU A 1 285 ? 184.770 140.466 186.220 1.00 109.93 ? 594 LEU B CD1 1 
ATOM 1791 C CD2 . LEU A 1 285 ? 186.628 141.545 187.467 1.00 109.93 ? 594 LEU B CD2 1 
ATOM 1792 N N   . LYS A 1 286 ? 186.703 138.534 183.411 1.00 94.31  ? 595 LYS B N   1 
ATOM 1793 C CA  . LYS A 1 286 ? 187.372 138.701 182.133 1.00 94.31  ? 595 LYS B CA  1 
ATOM 1794 C C   . LYS A 1 286 ? 187.252 140.090 181.528 1.00 94.31  ? 595 LYS B C   1 
ATOM 1795 O O   . LYS A 1 286 ? 188.101 140.449 180.704 1.00 94.31  ? 595 LYS B O   1 
ATOM 1796 C CB  . LYS A 1 286 ? 186.860 137.665 181.121 1.00 94.31  ? 595 LYS B CB  1 
ATOM 1797 C CG  . LYS A 1 286 ? 185.400 137.323 181.285 1.00 94.31  ? 595 LYS B CG  1 
ATOM 1798 C CD  . LYS A 1 286 ? 184.911 136.443 180.150 1.00 94.31  ? 595 LYS B CD  1 
ATOM 1799 C CE  . LYS A 1 286 ? 185.282 134.989 180.379 1.00 94.31  ? 595 LYS B CE  1 
ATOM 1800 N NZ  . LYS A 1 286 ? 184.670 134.074 179.377 1.00 94.31  ? 595 LYS B NZ  1 
ATOM 1801 N N   . GLU A 1 287 ? 186.247 140.885 181.891 1.00 94.63  ? 596 GLU B N   1 
ATOM 1802 C CA  . GLU A 1 287 ? 186.251 142.249 181.378 1.00 94.63  ? 596 GLU B CA  1 
ATOM 1803 C C   . GLU A 1 287 ? 185.604 143.197 182.375 1.00 94.63  ? 596 GLU B C   1 
ATOM 1804 O O   . GLU A 1 287 ? 184.631 142.851 183.051 1.00 94.63  ? 596 GLU B O   1 
ATOM 1805 C CB  . GLU A 1 287 ? 185.532 142.366 180.029 1.00 94.63  ? 596 GLU B CB  1 
ATOM 1806 C CG  . GLU A 1 287 ? 184.017 142.240 180.059 1.00 94.63  ? 596 GLU B CG  1 
ATOM 1807 C CD  . GLU A 1 287 ? 183.516 140.841 180.270 1.00 94.63  ? 596 GLU B CD  1 
ATOM 1808 O OE1 . GLU A 1 287 ? 182.518 140.476 179.614 1.00 94.63  ? 596 GLU B OE1 1 
ATOM 1809 O OE2 . GLU A 1 287 ? 184.074 140.118 181.122 1.00 94.63  ? 596 GLU B OE2 1 
ATOM 1810 N N   . LEU A 1 288 ? 186.164 144.403 182.441 1.00 85.88  ? 597 LEU B N   1 
ATOM 1811 C CA  . LEU A 1 288 ? 185.689 145.481 183.294 1.00 85.88  ? 597 LEU B CA  1 
ATOM 1812 C C   . LEU A 1 288 ? 185.526 146.730 182.439 1.00 85.88  ? 597 LEU B C   1 
ATOM 1813 O O   . LEU A 1 288 ? 186.314 146.962 181.518 1.00 85.88  ? 597 LEU B O   1 
ATOM 1814 C CB  . LEU A 1 288 ? 186.676 145.740 184.430 1.00 85.88  ? 597 LEU B CB  1 
ATOM 1815 C CG  . LEU A 1 288 ? 186.251 146.754 185.481 1.00 85.88  ? 597 LEU B CG  1 
ATOM 1816 C CD1 . LEU A 1 288 ? 185.011 146.232 186.160 1.00 85.88  ? 597 LEU B CD1 1 
ATOM 1817 C CD2 . LEU A 1 288 ? 187.356 146.993 186.487 1.00 85.88  ? 597 LEU B CD2 1 
ATOM 1818 N N   . TYR A 1 289 ? 184.511 147.537 182.736 1.00 80.97  ? 598 TYR B N   1 
ATOM 1819 C CA  . TYR A 1 289 ? 184.187 148.698 181.908 1.00 80.97  ? 598 TYR B CA  1 
ATOM 1820 C C   . TYR A 1 289 ? 184.301 149.981 182.731 1.00 80.97  ? 598 TYR B C   1 
ATOM 1821 O O   . TYR A 1 289 ? 183.328 150.457 183.319 1.00 80.97  ? 598 TYR B O   1 
ATOM 1822 C CB  . TYR A 1 289 ? 182.821 148.520 181.301 1.00 80.97  ? 598 TYR B CB  1 
ATOM 1823 C CG  . TYR A 1 289 ? 182.798 147.404 180.286 1.00 80.97  ? 598 TYR B CG  1 
ATOM 1824 C CD1 . TYR A 1 289 ? 183.905 147.151 179.492 1.00 80.97  ? 598 TYR B CD1 1 
ATOM 1825 C CD2 . TYR A 1 289 ? 181.678 146.600 180.121 1.00 80.97  ? 598 TYR B CD2 1 
ATOM 1826 C CE1 . TYR A 1 289 ? 183.901 146.129 178.558 1.00 80.97  ? 598 TYR B CE1 1 
ATOM 1827 C CE2 . TYR A 1 289 ? 181.664 145.573 179.188 1.00 80.97  ? 598 TYR B CE2 1 
ATOM 1828 C CZ  . TYR A 1 289 ? 182.779 145.345 178.409 1.00 80.97  ? 598 TYR B CZ  1 
ATOM 1829 N N   . LEU A 1 290 ? 185.500 150.558 182.745 1.00 84.45  ? 599 LEU B N   1 
ATOM 1830 C CA  . LEU A 1 290 ? 185.806 151.758 183.517 1.00 84.45  ? 599 LEU B CA  1 
ATOM 1831 C C   . LEU A 1 290 ? 185.619 152.976 182.622 1.00 84.45  ? 599 LEU B C   1 
ATOM 1832 O O   . LEU A 1 290 ? 186.375 153.172 181.667 1.00 84.45  ? 599 LEU B O   1 
ATOM 1833 C CB  . LEU A 1 290 ? 187.232 151.702 184.058 1.00 84.45  ? 599 LEU B CB  1 
ATOM 1834 C CG  . LEU A 1 290 ? 187.669 150.436 184.788 1.00 84.45  ? 599 LEU B CG  1 
ATOM 1835 C CD1 . LEU A 1 290 ? 188.320 149.473 183.831 1.00 84.45  ? 599 LEU B CD1 1 
ATOM 1836 C CD2 . LEU A 1 290 ? 188.642 150.805 185.869 1.00 84.45  ? 599 LEU B CD2 1 
ATOM 1837 N N   . VAL A 1 291 ? 184.618 153.796 182.929 1.00 94.15  ? 600 VAL B N   1 
ATOM 1838 C CA  . VAL A 1 291 ? 184.321 154.991 182.151 1.00 94.15  ? 600 VAL B CA  1 
ATOM 1839 C C   . VAL A 1 291 ? 184.105 156.166 183.091 1.00 94.15  ? 600 VAL B C   1 
ATOM 1840 O O   . VAL A 1 291 ? 183.341 156.061 184.058 1.00 94.15  ? 600 VAL B O   1 
ATOM 1841 C CB  . VAL A 1 291 ? 183.089 154.799 181.254 1.00 94.15  ? 600 VAL B CB  1 
ATOM 1842 C CG1 . VAL A 1 291 ? 182.750 156.095 180.546 1.00 94.15  ? 600 VAL B CG1 1 
ATOM 1843 C CG2 . VAL A 1 291 ? 183.347 153.706 180.246 1.00 94.15  ? 600 VAL B CG2 1 
ATOM 1844 N N   . SER A 1 292 ? 184.776 157.283 182.803 1.00 114.11 ? 601 SER B N   1 
ATOM 1845 C CA  . SER A 1 292 ? 184.538 158.566 183.459 1.00 114.11 ? 601 SER B CA  1 
ATOM 1846 C C   . SER A 1 292 ? 184.747 158.502 184.964 1.00 114.11 ? 601 SER B C   1 
ATOM 1847 O O   . SER A 1 292 ? 184.266 159.370 185.696 1.00 114.11 ? 601 SER B O   1 
ATOM 1848 C CB  . SER A 1 292 ? 183.130 159.087 183.151 1.00 114.11 ? 601 SER B CB  1 
ATOM 1849 O OG  . SER A 1 292 ? 182.177 158.518 184.033 1.00 114.11 ? 601 SER B OG  1 
ATOM 1850 N N   . CYS A 1 293 ? 185.458 157.493 185.445 1.00 122.64 ? 602 CYS B N   1 
ATOM 1851 C CA  . CYS A 1 293 ? 185.697 157.343 186.869 1.00 122.64 ? 602 CYS B CA  1 
ATOM 1852 C C   . CYS A 1 293 ? 186.872 158.205 187.297 1.00 122.64 ? 602 CYS B C   1 
ATOM 1853 O O   . CYS A 1 293 ? 187.816 158.427 186.535 1.00 122.64 ? 602 CYS B O   1 
ATOM 1854 C CB  . CYS A 1 293 ? 185.963 155.881 187.214 1.00 122.64 ? 602 CYS B CB  1 
ATOM 1855 S SG  . CYS A 1 293 ? 187.223 155.121 186.179 1.00 122.64 ? 602 CYS B SG  1 
ATOM 1856 N N   . LYS A 1 294 ? 186.806 158.702 188.530 1.00 131.04 ? 603 LYS B N   1 
ATOM 1857 C CA  . LYS A 1 294 ? 187.877 159.545 189.041 1.00 131.04 ? 603 LYS B CA  1 
ATOM 1858 C C   . LYS A 1 294 ? 189.032 158.696 189.556 1.00 131.04 ? 603 LYS B C   1 
ATOM 1859 O O   . LYS A 1 294 ? 189.414 158.795 190.726 1.00 131.04 ? 603 LYS B O   1 
ATOM 1860 C CB  . LYS A 1 294 ? 187.356 160.471 190.138 1.00 131.04 ? 603 LYS B CB  1 
ATOM 1861 C CG  . LYS A 1 294 ? 186.287 161.435 189.659 1.00 131.04 ? 603 LYS B CG  1 
ATOM 1862 C CD  . LYS A 1 294 ? 186.860 162.468 188.702 1.00 131.04 ? 603 LYS B CD  1 
ATOM 1863 C CE  . LYS A 1 294 ? 186.146 163.804 188.843 1.00 131.04 ? 603 LYS B CE  1 
ATOM 1864 N NZ  . LYS A 1 294 ? 186.280 164.655 187.628 1.00 131.04 ? 603 LYS B NZ  1 
ATOM 1865 N N   . ILE A 1 295 ? 189.586 157.848 188.688 1.00 126.99 ? 604 ILE B N   1 
ATOM 1866 C CA  . ILE A 1 295 ? 190.749 157.057 189.060 1.00 126.99 ? 604 ILE B CA  1 
ATOM 1867 C C   . ILE A 1 295 ? 192.017 157.843 188.759 1.00 126.99 ? 604 ILE B C   1 
ATOM 1868 O O   . ILE A 1 295 ? 192.022 158.782 187.951 1.00 126.99 ? 604 ILE B O   1 
ATOM 1869 C CB  . ILE A 1 295 ? 190.750 155.709 188.322 1.00 126.99 ? 604 ILE B CB  1 
ATOM 1870 C CG1 . ILE A 1 295 ? 190.654 155.941 186.817 1.00 126.99 ? 604 ILE B CG1 1 
ATOM 1871 C CG2 . ILE A 1 295 ? 189.602 154.851 188.806 1.00 126.99 ? 604 ILE B CG2 1 
ATOM 1872 C CD1 . ILE A 1 295 ? 190.862 154.696 186.008 1.00 126.99 ? 604 ILE B CD1 1 
ATOM 1873 N N   . THR A 1 296 ? 193.111 157.448 189.408 1.00 161.45 ? 605 THR B N   1 
ATOM 1874 C CA  . THR A 1 296 ? 194.396 158.132 189.291 1.00 161.45 ? 605 THR B CA  1 
ATOM 1875 C C   . THR A 1 296 ? 195.344 157.417 188.334 1.00 161.45 ? 605 THR B C   1 
ATOM 1876 O O   . THR A 1 296 ? 196.532 157.746 188.266 1.00 161.45 ? 605 THR B O   1 
ATOM 1877 C CB  . THR A 1 296 ? 195.038 158.283 190.666 1.00 161.45 ? 605 THR B CB  1 
ATOM 1878 O OG1 . THR A 1 296 ? 195.296 156.986 191.219 1.00 161.45 ? 605 THR B OG1 1 
ATOM 1879 C CG2 . THR A 1 296 ? 194.113 159.051 191.601 1.00 161.45 ? 605 THR B CG2 1 
ATOM 1880 N N   . ASP A 1 297 ? 194.836 156.437 187.588 1.00 168.05 ? 606 ASP B N   1 
ATOM 1881 C CA  . ASP A 1 297 ? 195.607 155.708 186.586 1.00 168.05 ? 606 ASP B CA  1 
ATOM 1882 C C   . ASP A 1 297 ? 196.873 155.087 187.162 1.00 168.05 ? 606 ASP B C   1 
ATOM 1883 O O   . ASP A 1 297 ? 197.924 155.092 186.515 1.00 168.05 ? 606 ASP B O   1 
ATOM 1884 C CB  . ASP A 1 297 ? 195.966 156.622 185.414 1.00 168.05 ? 606 ASP B CB  1 
ATOM 1885 C CG  . ASP A 1 297 ? 196.059 155.870 184.107 1.00 168.05 ? 606 ASP B CG  1 
ATOM 1886 O OD1 . ASP A 1 297 ? 195.537 156.374 183.096 1.00 168.05 ? 606 ASP B OD1 1 
ATOM 1887 O OD2 . ASP A 1 297 ? 196.638 154.766 184.092 1.00 168.05 ? 606 ASP B OD2 1 
ATOM 1888 N N   . TYR A 1 298 ? 196.786 154.560 188.382 1.00 179.53 ? 607 TYR B N   1 
ATOM 1889 C CA  . TYR A 1 298 ? 197.844 153.728 188.930 1.00 179.53 ? 607 TYR B CA  1 
ATOM 1890 C C   . TYR A 1 298 ? 197.413 152.290 189.160 1.00 179.53 ? 607 TYR B C   1 
ATOM 1891 O O   . TYR A 1 298 ? 198.274 151.410 189.255 1.00 179.53 ? 607 TYR B O   1 
ATOM 1892 C CB  . TYR A 1 298 ? 198.362 154.311 190.252 1.00 179.53 ? 607 TYR B CB  1 
ATOM 1893 C CG  . TYR A 1 298 ? 199.509 153.526 190.836 1.00 179.53 ? 607 TYR B CG  1 
ATOM 1894 C CD1 . TYR A 1 298 ? 200.736 153.474 190.195 1.00 179.53 ? 607 TYR B CD1 1 
ATOM 1895 C CD2 . TYR A 1 298 ? 199.356 152.818 192.019 1.00 179.53 ? 607 TYR B CD2 1 
ATOM 1896 C CE1 . TYR A 1 298 ? 201.785 152.749 190.723 1.00 179.53 ? 607 TYR B CE1 1 
ATOM 1897 C CE2 . TYR A 1 298 ? 200.397 152.090 192.555 1.00 179.53 ? 607 TYR B CE2 1 
ATOM 1898 C CZ  . TYR A 1 298 ? 201.610 152.059 191.903 1.00 179.53 ? 607 TYR B CZ  1 
ATOM 1899 N N   . ALA A 1 299 ? 196.108 152.030 189.226 1.00 214.83 ? 608 ALA B N   1 
ATOM 1900 C CA  . ALA A 1 299 ? 195.607 150.669 189.323 1.00 214.83 ? 608 ALA B CA  1 
ATOM 1901 C C   . ALA A 1 299 ? 195.789 149.889 188.033 1.00 214.83 ? 608 ALA B C   1 
ATOM 1902 O O   . ALA A 1 299 ? 195.545 148.680 188.020 1.00 214.83 ? 608 ALA B O   1 
ATOM 1903 C CB  . ALA A 1 299 ? 194.129 150.674 189.710 1.00 214.83 ? 608 ALA B CB  1 
ATOM 1904 N N   . LEU A 1 300 ? 196.189 150.555 186.952 1.00 231.49 ? 609 LEU B N   1 
ATOM 1905 C CA  . LEU A 1 300 ? 196.545 149.849 185.728 1.00 231.49 ? 609 LEU B CA  1 
ATOM 1906 C C   . LEU A 1 300 ? 197.701 148.887 185.975 1.00 231.49 ? 609 LEU B C   1 
ATOM 1907 O O   . LEU A 1 300 ? 197.613 147.691 185.667 1.00 231.49 ? 609 LEU B O   1 
ATOM 1908 C CB  . LEU A 1 300 ? 196.898 150.872 184.647 1.00 231.49 ? 609 LEU B CB  1 
ATOM 1909 C CG  . LEU A 1 300 ? 197.228 150.424 183.228 1.00 231.49 ? 609 LEU B CG  1 
ATOM 1910 C CD1 . LEU A 1 300 ? 196.691 151.416 182.218 1.00 231.49 ? 609 LEU B CD1 1 
ATOM 1911 C CD2 . LEU A 1 300 ? 198.724 150.331 183.101 1.00 231.49 ? 609 LEU B CD2 1 
ATOM 1912 N N   . ILE A 1 301 ? 198.788 149.389 186.560 1.00 230.50 ? 610 ILE B N   1 
ATOM 1913 C CA  . ILE A 1 301 ? 199.916 148.524 186.885 1.00 230.50 ? 610 ILE B CA  1 
ATOM 1914 C C   . ILE A 1 301 ? 199.519 147.533 187.971 1.00 230.50 ? 610 ILE B C   1 
ATOM 1915 O O   . ILE A 1 301 ? 200.009 146.400 188.007 1.00 230.50 ? 610 ILE B O   1 
ATOM 1916 C CB  . ILE A 1 301 ? 201.138 149.371 187.287 1.00 230.50 ? 610 ILE B CB  1 
ATOM 1917 C CG1 . ILE A 1 301 ? 201.602 150.209 186.098 1.00 230.50 ? 610 ILE B CG1 1 
ATOM 1918 C CG2 . ILE A 1 301 ? 202.285 148.487 187.750 1.00 230.50 ? 610 ILE B CG2 1 
ATOM 1919 C CD1 . ILE A 1 301 ? 201.864 149.397 184.857 1.00 230.50 ? 610 ILE B CD1 1 
ATOM 1920 N N   . ALA A 1 302 ? 198.616 147.939 188.866 1.00 231.96 ? 611 ALA B N   1 
ATOM 1921 C CA  . ALA A 1 302 ? 198.152 147.030 189.910 1.00 231.96 ? 611 ALA B CA  1 
ATOM 1922 C C   . ALA A 1 302 ? 197.438 145.820 189.319 1.00 231.96 ? 611 ALA B C   1 
ATOM 1923 O O   . ALA A 1 302 ? 197.647 144.688 189.769 1.00 231.96 ? 611 ALA B O   1 
ATOM 1924 C CB  . ALA A 1 302 ? 197.235 147.770 190.882 1.00 231.96 ? 611 ALA B CB  1 
ATOM 1925 N N   . ILE A 1 303 ? 196.586 146.036 188.318 1.00 219.80 ? 612 ILE B N   1 
ATOM 1926 C CA  . ILE A 1 303 ? 195.874 144.922 187.700 1.00 219.80 ? 612 ILE B CA  1 
ATOM 1927 C C   . ILE A 1 303 ? 196.786 144.164 186.743 1.00 219.80 ? 612 ILE B C   1 
ATOM 1928 O O   . ILE A 1 303 ? 196.539 142.990 186.448 1.00 219.80 ? 612 ILE B O   1 
ATOM 1929 C CB  . ILE A 1 303 ? 194.594 145.418 187.003 1.00 219.80 ? 612 ILE B CB  1 
ATOM 1930 C CG1 . ILE A 1 303 ? 193.600 144.271 186.817 1.00 219.80 ? 612 ILE B CG1 1 
ATOM 1931 C CG2 . ILE A 1 303 ? 194.913 146.061 185.662 1.00 219.80 ? 612 ILE B CG2 1 
ATOM 1932 C CD1 . ILE A 1 303 ? 192.191 144.728 186.509 1.00 219.80 ? 612 ILE B CD1 1 
ATOM 1933 N N   . GLY A 1 304 ? 197.843 144.811 186.240 1.00 237.35 ? 613 GLY B N   1 
ATOM 1934 C CA  . GLY A 1 304 ? 198.845 144.089 185.475 1.00 237.35 ? 613 GLY B CA  1 
ATOM 1935 C C   . GLY A 1 304 ? 199.798 143.268 186.318 1.00 237.35 ? 613 GLY B C   1 
ATOM 1936 O O   . GLY A 1 304 ? 200.444 142.354 185.796 1.00 237.35 ? 613 GLY B O   1 
ATOM 1937 N N   . ARG A 1 305 ? 199.902 143.586 187.606 1.00 241.13 ? 614 ARG B N   1 
ATOM 1938 C CA  . ARG A 1 305 ? 200.740 142.848 188.542 1.00 241.13 ? 614 ARG B CA  1 
ATOM 1939 C C   . ARG A 1 305 ? 199.956 141.726 189.214 1.00 241.13 ? 614 ARG B C   1 
ATOM 1940 O O   . ARG A 1 305 ? 200.382 140.566 189.207 1.00 241.13 ? 614 ARG B O   1 
ATOM 1941 C CB  . ARG A 1 305 ? 201.292 143.802 189.607 1.00 241.13 ? 614 ARG B CB  1 
ATOM 1942 C CG  . ARG A 1 305 ? 202.521 144.577 189.206 1.00 241.13 ? 614 ARG B CG  1 
ATOM 1943 C CD  . ARG A 1 305 ? 203.122 145.262 190.415 1.00 241.13 ? 614 ARG B CD  1 
ATOM 1944 N NE  . ARG A 1 305 ? 204.212 146.149 190.033 1.00 241.13 ? 614 ARG B NE  1 
ATOM 1945 C CZ  . ARG A 1 305 ? 205.384 145.737 189.572 1.00 241.13 ? 614 ARG B CZ  1 
ATOM 1946 N N   . TYR A 1 306 ? 198.810 142.062 189.802 1.00 242.30 ? 615 TYR B N   1 
ATOM 1947 C CA  . TYR A 1 306 ? 198.070 141.154 190.667 1.00 242.30 ? 615 TYR B CA  1 
ATOM 1948 C C   . TYR A 1 306 ? 196.979 140.383 189.938 1.00 242.30 ? 615 TYR B C   1 
ATOM 1949 O O   . TYR A 1 306 ? 196.368 139.495 190.541 1.00 242.30 ? 615 TYR B O   1 
ATOM 1950 C CB  . TYR A 1 306 ? 197.464 141.938 191.835 1.00 242.30 ? 615 TYR B CB  1 
ATOM 1951 C CG  . TYR A 1 306 ? 198.492 142.289 192.881 1.00 242.30 ? 615 TYR B CG  1 
ATOM 1952 C CD1 . TYR A 1 306 ? 199.197 141.300 193.559 1.00 242.30 ? 615 TYR B CD1 1 
ATOM 1953 C CD2 . TYR A 1 306 ? 198.784 143.613 193.165 1.00 242.30 ? 615 TYR B CD2 1 
ATOM 1954 C CE1 . TYR A 1 306 ? 200.148 141.625 194.510 1.00 242.30 ? 615 TYR B CE1 1 
ATOM 1955 C CE2 . TYR A 1 306 ? 199.730 143.946 194.107 1.00 242.30 ? 615 TYR B CE2 1 
ATOM 1956 C CZ  . TYR A 1 306 ? 200.410 142.951 194.777 1.00 242.30 ? 615 TYR B CZ  1 
ATOM 1957 N N   . SER A 1 307 ? 196.731 140.681 188.663 1.00 212.76 ? 616 SER B N   1 
ATOM 1958 C CA  . SER A 1 307 ? 195.747 139.947 187.877 1.00 212.76 ? 616 SER B CA  1 
ATOM 1959 C C   . SER A 1 307 ? 196.386 139.430 186.599 1.00 212.76 ? 616 SER B C   1 
ATOM 1960 O O   . SER A 1 307 ? 196.939 140.207 185.813 1.00 212.76 ? 616 SER B O   1 
ATOM 1961 C CB  . SER A 1 307 ? 194.533 140.810 187.532 1.00 212.76 ? 616 SER B CB  1 
ATOM 1962 O OG  . SER A 1 307 ? 193.644 140.115 186.672 1.00 212.76 ? 616 SER B OG  1 
ATOM 1963 N N   . MET A 1 308 ? 196.264 138.125 186.374 1.00 165.35 ? 617 MET B N   1 
ATOM 1964 C CA  . MET A 1 308 ? 196.818 137.483 185.195 1.00 165.35 ? 617 MET B CA  1 
ATOM 1965 C C   . MET A 1 308 ? 195.753 136.878 184.290 1.00 165.35 ? 617 MET B C   1 
ATOM 1966 O O   . MET A 1 308 ? 196.012 136.690 183.095 1.00 165.35 ? 617 MET B O   1 
ATOM 1967 C CB  . MET A 1 308 ? 197.853 136.428 185.635 1.00 165.35 ? 617 MET B CB  1 
ATOM 1968 C CG  . MET A 1 308 ? 198.261 135.327 184.655 1.00 165.35 ? 617 MET B CG  1 
ATOM 1969 S SD  . MET A 1 308 ? 196.988 134.130 184.168 1.00 165.35 ? 617 MET B SD  1 
ATOM 1970 C CE  . MET A 1 308 ? 196.819 133.164 185.664 1.00 165.35 ? 617 MET B CE  1 
ATOM 1971 N N   . THR A 1 309 ? 194.561 136.590 184.808 1.00 157.39 ? 618 THR B N   1 
ATOM 1972 C CA  . THR A 1 309 ? 193.476 135.994 184.027 1.00 157.39 ? 618 THR B CA  1 
ATOM 1973 C C   . THR A 1 309 ? 192.574 137.112 183.519 1.00 157.39 ? 618 THR B C   1 
ATOM 1974 O O   . THR A 1 309 ? 191.485 137.321 184.052 1.00 157.39 ? 618 THR B O   1 
ATOM 1975 C CB  . THR A 1 309 ? 192.680 135.007 184.881 1.00 157.39 ? 618 THR B CB  1 
ATOM 1976 O OG1 . THR A 1 309 ? 192.093 135.706 185.983 1.00 157.39 ? 618 THR B OG1 1 
ATOM 1977 C CG2 . THR A 1 309 ? 193.571 133.951 185.439 1.00 157.39 ? 618 THR B CG2 1 
ATOM 1978 N N   . ILE A 1 310 ? 193.020 137.822 182.482 1.00 145.63 ? 619 ILE B N   1 
ATOM 1979 C CA  . ILE A 1 310 ? 192.248 138.946 181.964 1.00 145.63 ? 619 ILE B CA  1 
ATOM 1980 C C   . ILE A 1 310 ? 192.705 139.251 180.543 1.00 145.63 ? 619 ILE B C   1 
ATOM 1981 O O   . ILE A 1 310 ? 193.880 139.072 180.206 1.00 145.63 ? 619 ILE B O   1 
ATOM 1982 C CB  . ILE A 1 310 ? 192.393 140.175 182.880 1.00 145.63 ? 619 ILE B CB  1 
ATOM 1983 C CG1 . ILE A 1 310 ? 191.415 141.274 182.462 1.00 145.63 ? 619 ILE B CG1 1 
ATOM 1984 C CG2 . ILE A 1 310 ? 193.810 140.705 182.827 1.00 145.63 ? 619 ILE B CG2 1 
ATOM 1985 C CD1 . ILE A 1 310 ? 191.244 142.354 183.509 1.00 145.63 ? 619 ILE B CD1 1 
ATOM 1986 N N   . GLU A 1 311 ? 191.777 139.684 179.686 1.00 146.12 ? 620 GLU B N   1 
ATOM 1987 C CA  . GLU A 1 311 ? 192.112 140.060 178.319 1.00 146.12 ? 620 GLU B CA  1 
ATOM 1988 C C   . GLU A 1 311 ? 191.429 141.333 177.854 1.00 146.12 ? 620 GLU B C   1 
ATOM 1989 O O   . GLU A 1 311 ? 191.881 141.924 176.869 1.00 146.12 ? 620 GLU B O   1 
ATOM 1990 C CB  . GLU A 1 311 ? 191.734 138.939 177.341 1.00 146.12 ? 620 GLU B CB  1 
ATOM 1991 C CG  . GLU A 1 311 ? 190.251 138.705 177.258 1.00 146.12 ? 620 GLU B CG  1 
ATOM 1992 C CD  . GLU A 1 311 ? 189.754 137.787 178.344 1.00 146.12 ? 620 GLU B CD  1 
ATOM 1993 O OE1 . GLU A 1 311 ? 190.567 137.367 179.196 1.00 146.12 ? 620 GLU B OE1 1 
ATOM 1994 O OE2 . GLU A 1 311 ? 188.545 137.486 178.345 1.00 146.12 ? 620 GLU B OE2 1 
ATOM 1995 N N   . THR A 1 312 ? 190.367 141.773 178.525 1.00 111.66 ? 621 THR B N   1 
ATOM 1996 C CA  . THR A 1 312 ? 189.589 142.929 178.109 1.00 111.66 ? 621 THR B CA  1 
ATOM 1997 C C   . THR A 1 312 ? 189.426 143.884 179.277 1.00 111.66 ? 621 THR B C   1 
ATOM 1998 O O   . THR A 1 312 ? 188.947 143.494 180.346 1.00 111.66 ? 621 THR B O   1 
ATOM 1999 C CB  . THR A 1 312 ? 188.212 142.517 177.591 1.00 111.66 ? 621 THR B CB  1 
ATOM 2000 O OG1 . THR A 1 312 ? 188.358 141.426 176.675 1.00 111.66 ? 621 THR B OG1 1 
ATOM 2001 C CG2 . THR A 1 312 ? 187.520 143.693 176.904 1.00 111.66 ? 621 THR B CG2 1 
ATOM 2002 N N   . VAL A 1 313 ? 189.814 145.134 179.062 1.00 97.35  ? 622 VAL B N   1 
ATOM 2003 C CA  . VAL A 1 313 ? 189.632 146.195 180.041 1.00 97.35  ? 622 VAL B CA  1 
ATOM 2004 C C   . VAL A 1 313 ? 189.372 147.480 179.275 1.00 97.35  ? 622 VAL B C   1 
ATOM 2005 O O   . VAL A 1 313 ? 190.081 147.797 178.316 1.00 97.35  ? 622 VAL B O   1 
ATOM 2006 C CB  . VAL A 1 313 ? 190.845 146.325 180.985 1.00 97.35  ? 622 VAL B CB  1 
ATOM 2007 C CG1 . VAL A 1 313 ? 192.105 146.692 180.222 1.00 97.35  ? 622 VAL B CG1 1 
ATOM 2008 C CG2 . VAL A 1 313 ? 190.568 147.361 182.041 1.00 97.35  ? 622 VAL B CG2 1 
ATOM 2009 N N   . ASP A 1 314 ? 188.342 148.207 179.673 1.00 84.86  ? 623 ASP B N   1 
ATOM 2010 C CA  . ASP A 1 314 ? 187.924 149.394 178.943 1.00 84.86  ? 623 ASP B CA  1 
ATOM 2011 C C   . ASP A 1 314 ? 188.111 150.609 179.834 1.00 84.86  ? 623 ASP B C   1 
ATOM 2012 O O   . ASP A 1 314 ? 187.392 150.777 180.824 1.00 84.86  ? 623 ASP B O   1 
ATOM 2013 C CB  . ASP A 1 314 ? 186.477 149.277 178.482 1.00 84.86  ? 623 ASP B CB  1 
ATOM 2014 C CG  . ASP A 1 314 ? 186.027 150.492 177.712 1.00 84.86  ? 623 ASP B CG  1 
ATOM 2015 O OD1 . ASP A 1 314 ? 186.498 150.681 176.574 1.00 84.86  ? 623 ASP B OD1 1 
ATOM 2016 O OD2 . ASP A 1 314 ? 185.207 151.264 178.244 1.00 84.86  ? 623 ASP B OD2 1 
ATOM 2017 N N   . VAL A 1 315 ? 189.069 151.453 179.477 1.00 80.65  ? 624 VAL B N   1 
ATOM 2018 C CA  . VAL A 1 315 ? 189.273 152.728 180.147 1.00 80.65  ? 624 VAL B CA  1 
ATOM 2019 C C   . VAL A 1 315 ? 188.469 153.761 179.371 1.00 80.65  ? 624 VAL B C   1 
ATOM 2020 O O   . VAL A 1 315 ? 188.762 154.045 178.208 1.00 80.65  ? 624 VAL B O   1 
ATOM 2021 C CB  . VAL A 1 315 ? 190.757 153.102 180.212 1.00 80.65  ? 624 VAL B CB  1 
ATOM 2022 C CG1 . VAL A 1 315 ? 190.928 154.491 180.799 1.00 80.65  ? 624 VAL B CG1 1 
ATOM 2023 C CG2 . VAL A 1 315 ? 191.527 152.076 181.027 1.00 80.65  ? 624 VAL B CG2 1 
ATOM 2024 N N   . GLY A 1 316 ? 187.444 154.312 180.007 1.00 89.13  ? 625 GLY B N   1 
ATOM 2025 C CA  . GLY A 1 316 ? 186.597 155.271 179.336 1.00 89.13  ? 625 GLY B CA  1 
ATOM 2026 C C   . GLY A 1 316 ? 187.173 156.669 179.351 1.00 89.13  ? 625 GLY B C   1 
ATOM 2027 O O   . GLY A 1 316 ? 188.355 156.874 179.061 1.00 89.13  ? 625 GLY B O   1 
ATOM 2028 N N   . TRP A 1 317 ? 186.338 157.642 179.700 1.00 107.04 ? 626 TRP B N   1 
ATOM 2029 C CA  . TRP A 1 317 ? 186.713 159.050 179.629 1.00 107.04 ? 626 TRP B CA  1 
ATOM 2030 C C   . TRP A 1 317 ? 187.453 159.476 180.901 1.00 107.04 ? 626 TRP B C   1 
ATOM 2031 O O   . TRP A 1 317 ? 186.949 160.225 181.738 1.00 107.04 ? 626 TRP B O   1 
ATOM 2032 C CB  . TRP A 1 317 ? 185.465 159.889 179.390 1.00 107.04 ? 626 TRP B CB  1 
ATOM 2033 C CG  . TRP A 1 317 ? 185.608 160.890 178.294 1.00 107.04 ? 626 TRP B CG  1 
ATOM 2034 C CD1 . TRP A 1 317 ? 186.293 162.062 178.350 1.00 107.04 ? 626 TRP B CD1 1 
ATOM 2035 C CD2 . TRP A 1 317 ? 185.074 160.776 176.968 1.00 107.04 ? 626 TRP B CD2 1 
ATOM 2036 N NE1 . TRP A 1 317 ? 186.213 162.719 177.154 1.00 107.04 ? 626 TRP B NE1 1 
ATOM 2037 C CE2 . TRP A 1 317 ? 185.484 161.971 176.269 1.00 107.04 ? 626 TRP B CE2 1 
ATOM 2038 C CE3 . TRP A 1 317 ? 184.296 159.766 176.335 1.00 107.04 ? 626 TRP B CE3 1 
ATOM 2039 C CZ2 . TRP A 1 317 ? 185.165 162.268 174.941 1.00 107.04 ? 626 TRP B CZ2 1 
ATOM 2040 C CZ3 . TRP A 1 317 ? 183.861 159.840 175.031 1.00 107.04 ? 626 TRP B CZ3 1 
ATOM 2041 N N   . CYS A 1 318 ? 188.678 158.972 181.036 1.00 137.88 ? 627 CYS B N   1 
ATOM 2042 C CA  . CYS A 1 318 ? 189.542 159.334 182.152 1.00 137.88 ? 627 CYS B CA  1 
ATOM 2043 C C   . CYS A 1 318 ? 190.326 160.591 181.806 1.00 137.88 ? 627 CYS B C   1 
ATOM 2044 O O   . CYS A 1 318 ? 190.973 160.656 180.755 1.00 137.88 ? 627 CYS B O   1 
ATOM 2045 C CB  . CYS A 1 318 ? 190.503 158.196 182.498 1.00 137.88 ? 627 CYS B CB  1 
ATOM 2046 S SG  . CYS A 1 318 ? 189.730 156.775 183.279 1.00 137.88 ? 627 CYS B SG  1 
ATOM 2047 N N   . LYS A 1 319 ? 190.266 161.585 182.693 1.00 148.43 ? 628 LYS B N   1 
ATOM 2048 C CA  . LYS A 1 319 ? 190.914 162.861 182.415 1.00 148.43 ? 628 LYS B CA  1 
ATOM 2049 C C   . LYS A 1 319 ? 192.421 162.701 182.279 1.00 148.43 ? 628 LYS B C   1 
ATOM 2050 O O   . LYS A 1 319 ? 193.037 163.297 181.389 1.00 148.43 ? 628 LYS B O   1 
ATOM 2051 C CB  . LYS A 1 319 ? 190.579 163.868 183.510 1.00 148.43 ? 628 LYS B CB  1 
ATOM 2052 C CG  . LYS A 1 319 ? 189.155 163.769 184.021 1.00 148.43 ? 628 LYS B CG  1 
ATOM 2053 C CD  . LYS A 1 319 ? 188.159 164.186 182.955 1.00 148.43 ? 628 LYS B CD  1 
ATOM 2054 C CE  . LYS A 1 319 ? 186.764 163.683 183.280 1.00 148.43 ? 628 LYS B CE  1 
ATOM 2055 N NZ  . LYS A 1 319 ? 186.437 163.879 184.718 1.00 148.43 ? 628 LYS B NZ  1 
ATOM 2056 N N   . GLU A 1 320 ? 193.033 161.902 183.148 1.00 159.19 ? 629 GLU B N   1 
ATOM 2057 C CA  . GLU A 1 320 ? 194.471 161.679 183.130 1.00 159.19 ? 629 GLU B CA  1 
ATOM 2058 C C   . GLU A 1 320 ? 194.752 160.243 182.719 1.00 159.19 ? 629 GLU B C   1 
ATOM 2059 O O   . GLU A 1 320 ? 194.246 159.302 183.340 1.00 159.19 ? 629 GLU B O   1 
ATOM 2060 C CB  . GLU A 1 320 ? 195.093 161.975 184.499 1.00 159.19 ? 629 GLU B CB  1 
ATOM 2061 C CG  . GLU A 1 320 ? 196.604 162.190 184.479 1.00 159.19 ? 629 GLU B CG  1 
ATOM 2062 C CD  . GLU A 1 320 ? 197.014 163.570 183.984 1.00 159.19 ? 629 GLU B CD  1 
ATOM 2063 O OE1 . GLU A 1 320 ? 198.176 163.959 184.219 1.00 159.19 ? 629 GLU B OE1 1 
ATOM 2064 O OE2 . GLU A 1 320 ? 196.182 164.266 183.366 1.00 159.19 ? 629 GLU B OE2 1 
ATOM 2065 N N   . ILE A 1 321 ? 195.558 160.081 181.674 1.00 185.79 ? 630 ILE B N   1 
ATOM 2066 C CA  . ILE A 1 321 ? 195.992 158.771 181.210 1.00 185.79 ? 630 ILE B CA  1 
ATOM 2067 C C   . ILE A 1 321 ? 197.513 158.768 181.151 1.00 185.79 ? 630 ILE B C   1 
ATOM 2068 O O   . ILE A 1 321 ? 198.120 159.602 180.472 1.00 185.79 ? 630 ILE B O   1 
ATOM 2069 C CB  . ILE A 1 321 ? 195.389 158.420 179.835 1.00 185.79 ? 630 ILE B CB  1 
ATOM 2070 C CG1 . ILE A 1 321 ? 193.869 158.275 179.939 1.00 185.79 ? 630 ILE B CG1 1 
ATOM 2071 C CG2 . ILE A 1 321 ? 196.014 157.143 179.296 1.00 185.79 ? 630 ILE B CG2 1 
ATOM 2072 C CD1 . ILE A 1 321 ? 193.430 157.155 180.845 1.00 185.79 ? 630 ILE B CD1 1 
ATOM 2073 N N   . THR A 1 322 ? 198.126 157.826 181.861 1.00 214.37 ? 631 THR B N   1 
ATOM 2074 C CA  . THR A 1 322 ? 199.580 157.753 181.962 1.00 214.37 ? 631 THR B CA  1 
ATOM 2075 C C   . THR A 1 322 ? 200.121 157.020 180.740 1.00 214.37 ? 631 THR B C   1 
ATOM 2076 O O   . THR A 1 322 ? 199.496 156.078 180.240 1.00 214.37 ? 631 THR B O   1 
ATOM 2077 C CB  . THR A 1 322 ? 200.003 157.067 183.259 1.00 214.37 ? 631 THR B CB  1 
ATOM 2078 O OG1 . THR A 1 322 ? 201.425 157.161 183.409 1.00 214.37 ? 631 THR B OG1 1 
ATOM 2079 C CG2 . THR A 1 322 ? 199.594 155.603 183.261 1.00 214.37 ? 631 THR B CG2 1 
ATOM 2080 N N   . ASP A 1 323 ? 201.259 157.490 180.224 1.00 240.32 ? 632 ASP B N   1 
ATOM 2081 C CA  . ASP A 1 323 ? 201.870 156.839 179.070 1.00 240.32 ? 632 ASP B CA  1 
ATOM 2082 C C   . ASP A 1 323 ? 202.869 155.766 179.493 1.00 240.32 ? 632 ASP B C   1 
ATOM 2083 O O   . ASP A 1 323 ? 202.958 154.709 178.858 1.00 240.32 ? 632 ASP B O   1 
ATOM 2084 C CB  . ASP A 1 323 ? 202.533 157.884 178.171 1.00 240.32 ? 632 ASP B CB  1 
ATOM 2085 C CG  . ASP A 1 323 ? 201.519 158.761 177.452 1.00 240.32 ? 632 ASP B CG  1 
ATOM 2086 O OD1 . ASP A 1 323 ? 200.407 158.949 177.990 1.00 240.32 ? 632 ASP B OD1 1 
ATOM 2087 O OD2 . ASP A 1 323 ? 201.829 159.258 176.348 1.00 240.32 ? 632 ASP B OD2 1 
ATOM 2088 N N   . GLN A 1 324 ? 203.638 156.014 180.558 1.00 244.54 ? 633 GLN B N   1 
ATOM 2089 C CA  . GLN A 1 324 ? 204.592 155.007 181.018 1.00 244.54 ? 633 GLN B CA  1 
ATOM 2090 C C   . GLN A 1 324 ? 203.884 153.808 181.638 1.00 244.54 ? 633 GLN B C   1 
ATOM 2091 O O   . GLN A 1 324 ? 204.342 152.668 181.495 1.00 244.54 ? 633 GLN B O   1 
ATOM 2092 C CB  . GLN A 1 324 ? 205.576 155.605 182.018 1.00 244.54 ? 633 GLN B CB  1 
ATOM 2093 C CG  . GLN A 1 324 ? 206.865 154.807 182.104 1.00 244.54 ? 633 GLN B CG  1 
ATOM 2094 C CD  . GLN A 1 324 ? 206.856 153.810 183.247 1.00 244.54 ? 633 GLN B CD  1 
ATOM 2095 O OE1 . GLN A 1 324 ? 206.050 153.916 184.172 1.00 244.54 ? 633 GLN B OE1 1 
ATOM 2096 N NE2 . GLN A 1 324 ? 207.746 152.828 183.183 1.00 244.54 ? 633 GLN B NE2 1 
ATOM 2097 N N   . GLY A 1 325 ? 202.790 154.044 182.363 1.00 244.26 ? 634 GLY B N   1 
ATOM 2098 C CA  . GLY A 1 325 ? 202.030 152.927 182.898 1.00 244.26 ? 634 GLY B CA  1 
ATOM 2099 C C   . GLY A 1 325 ? 201.481 152.039 181.798 1.00 244.26 ? 634 GLY B C   1 
ATOM 2100 O O   . GLY A 1 325 ? 201.541 150.810 181.886 1.00 244.26 ? 634 GLY B O   1 
ATOM 2101 N N   . ALA A 1 326 ? 200.960 152.653 180.736 1.00 247.38 ? 635 ALA B N   1 
ATOM 2102 C CA  . ALA A 1 326 ? 200.541 151.885 179.572 1.00 247.38 ? 635 ALA B CA  1 
ATOM 2103 C C   . ALA A 1 326 ? 201.725 151.174 178.932 1.00 247.38 ? 635 ALA B C   1 
ATOM 2104 O O   . ALA A 1 326 ? 201.598 150.042 178.453 1.00 247.38 ? 635 ALA B O   1 
ATOM 2105 C CB  . ALA A 1 326 ? 199.845 152.799 178.564 1.00 247.38 ? 635 ALA B CB  1 
ATOM 2106 N N   . THR A 1 327 ? 202.891 151.824 178.912 1.00 255.34 ? 636 THR B N   1 
ATOM 2107 C CA  . THR A 1 327 ? 204.080 151.173 178.374 1.00 255.34 ? 636 THR B CA  1 
ATOM 2108 C C   . THR A 1 327 ? 204.398 149.903 179.150 1.00 255.34 ? 636 THR B C   1 
ATOM 2109 O O   . THR A 1 327 ? 204.741 148.873 178.561 1.00 255.34 ? 636 THR B O   1 
ATOM 2110 C CB  . THR A 1 327 ? 205.269 152.133 178.413 1.00 255.34 ? 636 THR B CB  1 
ATOM 2111 O OG1 . THR A 1 327 ? 204.898 153.386 177.824 1.00 255.34 ? 636 THR B OG1 1 
ATOM 2112 C CG2 . THR A 1 327 ? 206.445 151.550 177.653 1.00 255.34 ? 636 THR B CG2 1 
ATOM 2113 N N   . LEU A 1 328 ? 204.280 149.961 180.474 1.00 255.75 ? 637 LEU B N   1 
ATOM 2114 C CA  . LEU A 1 328 ? 204.554 148.788 181.296 1.00 255.75 ? 637 LEU B CA  1 
ATOM 2115 C C   . LEU A 1 328 ? 203.482 147.719 181.120 1.00 255.75 ? 637 LEU B C   1 
ATOM 2116 O O   . LEU A 1 328 ? 203.790 146.524 181.108 1.00 255.75 ? 637 LEU B O   1 
ATOM 2117 C CB  . LEU A 1 328 ? 204.695 149.187 182.763 1.00 255.75 ? 637 LEU B CB  1 
ATOM 2118 C CG  . LEU A 1 328 ? 206.065 149.754 183.135 1.00 255.75 ? 637 LEU B CG  1 
ATOM 2119 C CD1 . LEU A 1 328 ? 206.179 149.935 184.634 1.00 255.75 ? 637 LEU B CD1 1 
ATOM 2120 C CD2 . LEU A 1 328 ? 207.167 148.843 182.624 1.00 255.75 ? 637 LEU B CD2 1 
ATOM 2121 N N   . ILE A 1 329 ? 202.214 148.121 180.993 1.00 259.17 ? 638 ILE B N   1 
ATOM 2122 C CA  . ILE A 1 329 ? 201.171 147.117 180.781 1.00 259.17 ? 638 ILE B CA  1 
ATOM 2123 C C   . ILE A 1 329 ? 201.284 146.483 179.402 1.00 259.17 ? 638 ILE B C   1 
ATOM 2124 O O   . ILE A 1 329 ? 200.778 145.374 179.190 1.00 259.17 ? 638 ILE B O   1 
ATOM 2125 C CB  . ILE A 1 329 ? 199.758 147.698 180.989 1.00 259.17 ? 638 ILE B CB  1 
ATOM 2126 C CG1 . ILE A 1 329 ? 198.719 146.580 181.075 1.00 259.17 ? 638 ILE B CG1 1 
ATOM 2127 C CG2 . ILE A 1 329 ? 199.356 148.583 179.843 1.00 259.17 ? 638 ILE B CG2 1 
ATOM 2128 C CD1 . ILE A 1 329 ? 198.867 145.696 182.277 1.00 259.17 ? 638 ILE B CD1 1 
ATOM 2129 N N   . ALA A 1 330 ? 201.949 147.153 178.456 1.00 266.92 ? 639 ALA B N   1 
ATOM 2130 C CA  . ALA A 1 330 ? 202.118 146.579 177.124 1.00 266.92 ? 639 ALA B CA  1 
ATOM 2131 C C   . ALA A 1 330 ? 202.865 145.252 177.180 1.00 266.92 ? 639 ALA B C   1 
ATOM 2132 O O   . ALA A 1 330 ? 202.600 144.347 176.381 1.00 266.92 ? 639 ALA B O   1 
ATOM 2133 C CB  . ALA A 1 330 ? 202.846 147.567 176.214 1.00 266.92 ? 639 ALA B CB  1 
ATOM 2134 N N   . GLN A 1 331 ? 203.802 145.116 178.120 1.00 272.08 ? 640 GLN B N   1 
ATOM 2135 C CA  . GLN A 1 331 ? 204.543 143.876 178.314 1.00 272.08 ? 640 GLN B CA  1 
ATOM 2136 C C   . GLN A 1 331 ? 204.281 143.245 179.677 1.00 272.08 ? 640 GLN B C   1 
ATOM 2137 O O   . GLN A 1 331 ? 204.962 142.278 180.040 1.00 272.08 ? 640 GLN B O   1 
ATOM 2138 C CB  . GLN A 1 331 ? 206.044 144.115 178.123 1.00 272.08 ? 640 GLN B CB  1 
ATOM 2139 C CG  . GLN A 1 331 ? 206.622 145.175 179.038 1.00 272.08 ? 640 GLN B CG  1 
ATOM 2140 C CD  . GLN A 1 331 ? 206.599 146.547 178.397 1.00 272.08 ? 640 GLN B CD  1 
ATOM 2141 O OE1 . GLN A 1 331 ? 205.930 146.756 177.386 1.00 272.08 ? 640 GLN B OE1 1 
ATOM 2142 N NE2 . GLN A 1 331 ? 207.323 147.492 178.984 1.00 272.08 ? 640 GLN B NE2 1 
ATOM 2143 N N   . SER A 1 332 ? 203.329 143.776 180.446 1.00 287.22 ? 641 SER B N   1 
ATOM 2144 C CA  . SER A 1 332 ? 203.035 143.207 181.759 1.00 287.22 ? 641 SER B CA  1 
ATOM 2145 C C   . SER A 1 332 ? 202.290 141.882 181.647 1.00 287.22 ? 641 SER B C   1 
ATOM 2146 O O   . SER A 1 332 ? 202.642 140.909 182.321 1.00 287.22 ? 641 SER B O   1 
ATOM 2147 C CB  . SER A 1 332 ? 202.226 144.203 182.590 1.00 287.22 ? 641 SER B CB  1 
ATOM 2148 O OG  . SER A 1 332 ? 202.129 143.779 183.937 1.00 287.22 ? 641 SER B OG  1 
ATOM 2149 N N   . SER A 1 333 ? 201.260 141.822 180.807 1.00 307.47 ? 642 SER B N   1 
ATOM 2150 C CA  . SER A 1 333 ? 200.403 140.648 180.711 1.00 307.47 ? 642 SER B CA  1 
ATOM 2151 C C   . SER A 1 333 ? 200.580 139.957 179.364 1.00 307.47 ? 642 SER B C   1 
ATOM 2152 O O   . SER A 1 333 ? 201.169 140.500 178.426 1.00 307.47 ? 642 SER B O   1 
ATOM 2153 C CB  . SER A 1 333 ? 198.931 141.026 180.925 1.00 307.47 ? 642 SER B CB  1 
ATOM 2154 O OG  . SER A 1 333 ? 198.091 139.888 180.805 1.00 307.47 ? 642 SER B OG  1 
ATOM 2155 N N   . LYS A 1 334 ? 200.046 138.737 179.282 1.00 277.91 ? 643 LYS B N   1 
ATOM 2156 C CA  . LYS A 1 334 ? 200.207 137.896 178.105 1.00 277.91 ? 643 LYS B CA  1 
ATOM 2157 C C   . LYS A 1 334 ? 198.953 137.784 177.248 1.00 277.91 ? 643 LYS B C   1 
ATOM 2158 O O   . LYS A 1 334 ? 199.021 137.200 176.163 1.00 277.91 ? 643 LYS B O   1 
ATOM 2159 C CB  . LYS A 1 334 ? 200.653 136.487 178.520 1.00 277.91 ? 643 LYS B CB  1 
ATOM 2160 C CG  . LYS A 1 334 ? 202.096 136.424 178.986 1.00 277.91 ? 643 LYS B CG  1 
ATOM 2161 C CD  . LYS A 1 334 ? 202.466 135.045 179.502 1.00 277.91 ? 643 LYS B CD  1 
ATOM 2162 C CE  . LYS A 1 334 ? 203.903 135.021 180.009 1.00 277.91 ? 643 LYS B CE  1 
ATOM 2163 N NZ  . LYS A 1 334 ? 204.563 133.708 179.770 1.00 277.91 ? 643 LYS B NZ  1 
ATOM 2164 N N   . SER A 1 335 ? 197.817 138.319 177.700 1.00 244.54 ? 644 SER B N   1 
ATOM 2165 C CA  . SER A 1 335 ? 196.552 138.142 176.997 1.00 244.54 ? 644 SER B CA  1 
ATOM 2166 C C   . SER A 1 335 ? 195.886 139.464 176.624 1.00 244.54 ? 644 SER B C   1 
ATOM 2167 O O   . SER A 1 335 ? 194.657 139.525 176.528 1.00 244.54 ? 644 SER B O   1 
ATOM 2168 C CB  . SER A 1 335 ? 195.604 137.291 177.843 1.00 244.54 ? 644 SER B CB  1 
ATOM 2169 O OG  . SER A 1 335 ? 195.178 138.001 178.991 1.00 244.54 ? 644 SER B OG  1 
ATOM 2170 N N   . LEU A 1 336 ? 196.660 140.522 176.386 1.00 252.12 ? 645 LEU B N   1 
ATOM 2171 C CA  . LEU A 1 336 ? 196.114 141.860 176.154 1.00 252.12 ? 645 LEU B CA  1 
ATOM 2172 C C   . LEU A 1 336 ? 196.545 142.389 174.788 1.00 252.12 ? 645 LEU B C   1 
ATOM 2173 O O   . LEU A 1 336 ? 197.680 142.842 174.617 1.00 252.12 ? 645 LEU B O   1 
ATOM 2174 C CB  . LEU A 1 336 ? 196.550 142.813 177.263 1.00 252.12 ? 645 LEU B CB  1 
ATOM 2175 C CG  . LEU A 1 336 ? 196.163 144.282 177.081 1.00 252.12 ? 645 LEU B CG  1 
ATOM 2176 C CD1 . LEU A 1 336 ? 194.656 144.436 176.929 1.00 252.12 ? 645 LEU B CD1 1 
ATOM 2177 C CD2 . LEU A 1 336 ? 196.676 145.116 178.244 1.00 252.12 ? 645 LEU B CD2 1 
ATOM 2178 N N   . ARG A 1 337 ? 195.632 142.331 173.813 1.00 252.53 ? 646 ARG B N   1 
ATOM 2179 C CA  . ARG A 1 337 ? 195.773 143.061 172.551 1.00 252.53 ? 646 ARG B CA  1 
ATOM 2180 C C   . ARG A 1 337 ? 194.431 143.738 172.280 1.00 252.53 ? 646 ARG B C   1 
ATOM 2181 O O   . ARG A 1 337 ? 193.607 143.226 171.521 1.00 252.53 ? 646 ARG B O   1 
ATOM 2182 C CB  . ARG A 1 337 ? 196.168 142.140 171.410 1.00 252.53 ? 646 ARG B CB  1 
ATOM 2183 C CG  . ARG A 1 337 ? 196.668 140.770 171.825 1.00 252.53 ? 646 ARG B CG  1 
ATOM 2184 C CD  . ARG A 1 337 ? 198.137 140.787 172.172 1.00 252.53 ? 646 ARG B CD  1 
ATOM 2185 N NE  . ARG A 1 337 ? 198.486 139.685 173.059 1.00 252.53 ? 646 ARG B NE  1 
ATOM 2186 C CZ  . ARG A 1 337 ? 199.726 139.342 173.376 1.00 252.53 ? 646 ARG B CZ  1 
ATOM 2187 N N   . TYR A 1 338 ? 194.214 144.897 172.893 1.00 254.04 ? 647 TYR B N   1 
ATOM 2188 C CA  . TYR A 1 338 ? 192.951 145.613 172.753 1.00 254.04 ? 647 TYR B CA  1 
ATOM 2189 C C   . TYR A 1 338 ? 193.232 147.106 172.616 1.00 254.04 ? 647 TYR B C   1 
ATOM 2190 O O   . TYR A 1 338 ? 192.555 147.950 173.205 1.00 254.04 ? 647 TYR B O   1 
ATOM 2191 C CB  . TYR A 1 338 ? 192.039 145.316 173.943 1.00 254.04 ? 647 TYR B CB  1 
ATOM 2192 C CG  . TYR A 1 338 ? 190.555 145.398 173.651 1.00 254.04 ? 647 TYR B CG  1 
ATOM 2193 C CD1 . TYR A 1 338 ? 189.942 144.474 172.816 1.00 254.04 ? 647 TYR B CD1 1 
ATOM 2194 C CD2 . TYR A 1 338 ? 189.767 146.395 174.211 1.00 254.04 ? 647 TYR B CD2 1 
ATOM 2195 C CE1 . TYR A 1 338 ? 188.585 144.537 172.550 1.00 254.04 ? 647 TYR B CE1 1 
ATOM 2196 C CE2 . TYR A 1 338 ? 188.408 146.468 173.948 1.00 254.04 ? 647 TYR B CE2 1 
ATOM 2197 C CZ  . TYR A 1 338 ? 187.825 145.537 173.117 1.00 254.04 ? 647 TYR B CZ  1 
ATOM 2198 N N   . LEU A 1 339 ? 194.253 147.448 171.827 1.00 270.43 ? 648 LEU B N   1 
ATOM 2199 C CA  . LEU A 1 339 ? 194.773 148.815 171.774 1.00 270.43 ? 648 LEU B CA  1 
ATOM 2200 C C   . LEU A 1 339 ? 193.911 149.655 170.837 1.00 270.43 ? 648 LEU B C   1 
ATOM 2201 O O   . LEU A 1 339 ? 194.333 150.087 169.763 1.00 270.43 ? 648 LEU B O   1 
ATOM 2202 C CB  . LEU A 1 339 ? 196.235 148.814 171.344 1.00 270.43 ? 648 LEU B CB  1 
ATOM 2203 C CG  . LEU A 1 339 ? 197.265 148.528 172.437 1.00 270.43 ? 648 LEU B CG  1 
ATOM 2204 C CD1 . LEU A 1 339 ? 197.386 147.039 172.708 1.00 270.43 ? 648 LEU B CD1 1 
ATOM 2205 C CD2 . LEU A 1 339 ? 198.610 149.109 172.048 1.00 270.43 ? 648 LEU B CD2 1 
ATOM 2206 N N   . GLY A 1 340 ? 192.681 149.907 171.273 1.00 289.52 ? 649 GLY B N   1 
ATOM 2207 C CA  . GLY A 1 340 ? 191.795 150.790 170.542 1.00 289.52 ? 649 GLY B CA  1 
ATOM 2208 C C   . GLY A 1 340 ? 192.024 152.239 170.913 1.00 289.52 ? 649 GLY B C   1 
ATOM 2209 O O   . GLY A 1 340 ? 191.126 152.902 171.438 1.00 289.52 ? 649 GLY B O   1 
ATOM 2210 N N   . LEU A 1 341 ? 193.227 152.738 170.636 1.00 262.42 ? 650 LEU B N   1 
ATOM 2211 C CA  . LEU A 1 341 ? 193.621 154.068 171.077 1.00 262.42 ? 650 LEU B CA  1 
ATOM 2212 C C   . LEU A 1 341 ? 192.705 155.133 170.486 1.00 262.42 ? 650 LEU B C   1 
ATOM 2213 O O   . LEU A 1 341 ? 192.509 155.203 169.271 1.00 262.42 ? 650 LEU B O   1 
ATOM 2214 C CB  . LEU A 1 341 ? 195.067 154.345 170.670 1.00 262.42 ? 650 LEU B CB  1 
ATOM 2215 C CG  . LEU A 1 341 ? 196.174 153.802 171.575 1.00 262.42 ? 650 LEU B CG  1 
ATOM 2216 C CD1 . LEU A 1 341 ? 197.530 154.134 170.986 1.00 262.42 ? 650 LEU B CD1 1 
ATOM 2217 C CD2 . LEU A 1 341 ? 196.055 154.346 172.988 1.00 262.42 ? 650 LEU B CD2 1 
ATOM 2218 N N   . MET A 1 342 ? 192.153 155.977 171.355 1.00 233.90 ? 651 MET B N   1 
ATOM 2219 C CA  . MET A 1 342 ? 191.208 156.990 170.913 1.00 233.90 ? 651 MET B CA  1 
ATOM 2220 C C   . MET A 1 342 ? 191.196 158.124 171.929 1.00 233.90 ? 651 MET B C   1 
ATOM 2221 O O   . MET A 1 342 ? 191.520 157.923 173.104 1.00 233.90 ? 651 MET B O   1 
ATOM 2222 C CB  . MET A 1 342 ? 189.810 156.391 170.733 1.00 233.90 ? 651 MET B CB  1 
ATOM 2223 C CG  . MET A 1 342 ? 189.479 156.043 169.292 1.00 233.90 ? 651 MET B CG  1 
ATOM 2224 S SD  . MET A 1 342 ? 189.119 157.485 168.291 1.00 233.90 ? 651 MET B SD  1 
ATOM 2225 C CE  . MET A 1 342 ? 187.414 157.704 168.747 1.00 233.90 ? 651 MET B CE  1 
ATOM 2226 N N   . ARG A 1 343 ? 190.813 159.316 171.463 1.00 247.99 ? 652 ARG B N   1 
ATOM 2227 C CA  . ARG A 1 343 ? 190.936 160.547 172.249 1.00 247.99 ? 652 ARG B CA  1 
ATOM 2228 C C   . ARG A 1 343 ? 192.365 160.712 172.752 1.00 247.99 ? 652 ARG B C   1 
ATOM 2229 O O   . ARG A 1 343 ? 192.607 161.090 173.901 1.00 247.99 ? 652 ARG B O   1 
ATOM 2230 C CB  . ARG A 1 343 ? 189.936 160.577 173.407 1.00 247.99 ? 652 ARG B CB  1 
ATOM 2231 C CG  . ARG A 1 343 ? 189.417 161.970 173.723 1.00 247.99 ? 652 ARG B CG  1 
ATOM 2232 C CD  . ARG A 1 343 ? 188.082 162.240 173.052 1.00 247.99 ? 652 ARG B CD  1 
ATOM 2233 N NE  . ARG A 1 343 ? 187.861 163.662 172.819 1.00 247.99 ? 652 ARG B NE  1 
ATOM 2234 C CZ  . ARG A 1 343 ? 187.710 164.566 173.777 1.00 247.99 ? 652 ARG B CZ  1 
ATOM 2235 N N   . CYS A 1 344 ? 193.322 160.425 171.873 1.00 315.92 ? 653 CYS B N   1 
ATOM 2236 C CA  . CYS A 1 344 ? 194.727 160.311 172.256 1.00 315.92 ? 653 CYS B CA  1 
ATOM 2237 C C   . CYS A 1 344 ? 195.455 161.628 171.995 1.00 315.92 ? 653 CYS B C   1 
ATOM 2238 O O   . CYS A 1 344 ? 196.258 161.769 171.071 1.00 315.92 ? 653 CYS B O   1 
ATOM 2239 C CB  . CYS A 1 344 ? 195.380 159.153 171.509 1.00 315.92 ? 653 CYS B CB  1 
ATOM 2240 S SG  . CYS A 1 344 ? 194.743 157.540 171.986 1.00 315.92 ? 653 CYS B SG  1 
ATOM 2241 N N   . ASP A 1 345 ? 195.155 162.607 172.849 1.00 342.86 ? 654 ASP B N   1 
ATOM 2242 C CA  . ASP A 1 345 ? 195.900 163.858 172.819 1.00 342.86 ? 654 ASP B CA  1 
ATOM 2243 C C   . ASP A 1 345 ? 197.269 163.713 173.472 1.00 342.86 ? 654 ASP B C   1 
ATOM 2244 O O   . ASP A 1 345 ? 198.234 164.342 173.025 1.00 342.86 ? 654 ASP B O   1 
ATOM 2245 C CB  . ASP A 1 345 ? 195.096 164.969 173.497 1.00 342.86 ? 654 ASP B CB  1 
ATOM 2246 C CG  . ASP A 1 345 ? 193.960 165.476 172.628 1.00 342.86 ? 654 ASP B CG  1 
ATOM 2247 O OD1 . ASP A 1 345 ? 194.103 165.459 171.387 1.00 342.86 ? 654 ASP B OD1 1 
ATOM 2248 O OD2 . ASP A 1 345 ? 192.924 165.896 173.186 1.00 342.86 ? 654 ASP B OD2 1 
ATOM 2249 N N   . LYS A 1 346 ? 197.375 162.896 174.520 1.00 316.20 ? 655 LYS B N   1 
ATOM 2250 C CA  . LYS A 1 346 ? 198.654 162.654 175.186 1.00 316.20 ? 655 LYS B CA  1 
ATOM 2251 C C   . LYS A 1 346 ? 199.256 161.335 174.698 1.00 316.20 ? 655 LYS B C   1 
ATOM 2252 O O   . LYS A 1 346 ? 199.260 160.314 175.388 1.00 316.20 ? 655 LYS B O   1 
ATOM 2253 C CB  . LYS A 1 346 ? 198.475 162.669 176.702 1.00 316.20 ? 655 LYS B CB  1 
ATOM 2254 C CG  . LYS A 1 346 ? 199.763 162.962 177.456 1.00 316.20 ? 655 LYS B CG  1 
ATOM 2255 C CD  . LYS A 1 346 ? 200.326 164.322 177.062 1.00 316.20 ? 655 LYS B CD  1 
ATOM 2256 C CE  . LYS A 1 346 ? 201.601 164.647 177.822 1.00 316.20 ? 655 LYS B CE  1 
ATOM 2257 N NZ  . LYS A 1 346 ? 202.217 165.913 177.333 1.00 316.20 ? 655 LYS B NZ  1 
ATOM 2258 N N   . VAL A 1 347 ? 199.776 161.380 173.472 1.00 310.42 ? 656 VAL B N   1 
ATOM 2259 C CA  . VAL A 1 347 ? 200.435 160.230 172.865 1.00 310.42 ? 656 VAL B CA  1 
ATOM 2260 C C   . VAL A 1 347 ? 201.616 160.733 172.049 1.00 310.42 ? 656 VAL B C   1 
ATOM 2261 O O   . VAL A 1 347 ? 201.605 161.853 171.532 1.00 310.42 ? 656 VAL B O   1 
ATOM 2262 C CB  . VAL A 1 347 ? 199.461 159.401 171.990 1.00 310.42 ? 656 VAL B CB  1 
ATOM 2263 C CG1 . VAL A 1 347 ? 199.163 160.115 170.679 1.00 310.42 ? 656 VAL B CG1 1 
ATOM 2264 C CG2 . VAL A 1 347 ? 200.023 158.013 171.732 1.00 310.42 ? 656 VAL B CG2 1 
ATOM 2265 N N   . ASN A 1 348 ? 202.651 159.903 171.955 1.00 313.63 ? 657 ASN B N   1 
ATOM 2266 C CA  . ASN A 1 348 ? 203.803 160.201 171.123 1.00 313.63 ? 657 ASN B CA  1 
ATOM 2267 C C   . ASN A 1 348 ? 203.664 159.489 169.785 1.00 313.63 ? 657 ASN B C   1 
ATOM 2268 O O   . ASN A 1 348 ? 202.685 158.791 169.515 1.00 313.63 ? 657 ASN B O   1 
ATOM 2269 C CB  . ASN A 1 348 ? 205.104 159.808 171.825 1.00 313.63 ? 657 ASN B CB  1 
ATOM 2270 C CG  . ASN A 1 348 ? 206.243 160.757 171.505 1.00 313.63 ? 657 ASN B CG  1 
ATOM 2271 O OD1 . ASN A 1 348 ? 206.061 161.743 170.790 1.00 313.63 ? 657 ASN B OD1 1 
ATOM 2272 N ND2 . ASN A 1 348 ? 207.423 160.467 172.038 1.00 313.63 ? 657 ASN B ND2 1 
ATOM 2273 N N   . GLU A 1 349 ? 204.666 159.671 168.932 1.00 332.78 ? 658 GLU B N   1 
ATOM 2274 C CA  . GLU A 1 349 ? 204.646 159.125 167.583 1.00 332.78 ? 658 GLU B CA  1 
ATOM 2275 C C   . GLU A 1 349 ? 205.735 158.078 167.398 1.00 332.78 ? 658 GLU B C   1 
ATOM 2276 O O   . GLU A 1 349 ? 206.245 157.891 166.292 1.00 332.78 ? 658 GLU B O   1 
ATOM 2277 C CB  . GLU A 1 349 ? 204.792 160.244 166.555 1.00 332.78 ? 658 GLU B CB  1 
ATOM 2278 C CG  . GLU A 1 349 ? 203.727 161.317 166.678 1.00 332.78 ? 658 GLU B CG  1 
ATOM 2279 C CD  . GLU A 1 349 ? 204.147 162.449 167.593 1.00 332.78 ? 658 GLU B CD  1 
ATOM 2280 O OE1 . GLU A 1 349 ? 205.356 162.569 167.882 1.00 332.78 ? 658 GLU B OE1 1 
ATOM 2281 O OE2 . GLU A 1 349 ? 203.266 163.222 168.027 1.00 332.78 ? 658 GLU B OE2 1 
ATOM 2282 N N   . VAL A 1 350 ? 206.103 157.387 168.477 1.00 317.70 ? 659 VAL B N   1 
ATOM 2283 C CA  . VAL A 1 350 ? 207.158 156.387 168.450 1.00 317.70 ? 659 VAL B CA  1 
ATOM 2284 C C   . VAL A 1 350 ? 206.624 155.008 168.819 1.00 317.70 ? 659 VAL B C   1 
ATOM 2285 O O   . VAL A 1 350 ? 206.858 154.028 168.113 1.00 317.70 ? 659 VAL B O   1 
ATOM 2286 C CB  . VAL A 1 350 ? 208.330 156.782 169.373 1.00 317.70 ? 659 VAL B CB  1 
ATOM 2287 C CG1 . VAL A 1 350 ? 209.253 155.596 169.596 1.00 317.70 ? 659 VAL B CG1 1 
ATOM 2288 C CG2 . VAL A 1 350 ? 209.097 157.970 168.798 1.00 317.70 ? 659 VAL B CG2 1 
ATOM 2289 N N   . THR A 1 351 ? 205.907 154.916 169.935 1.00 304.54 ? 660 THR B N   1 
ATOM 2290 C CA  . THR A 1 351 ? 205.262 153.661 170.292 1.00 304.54 ? 660 THR B CA  1 
ATOM 2291 C C   . THR A 1 351 ? 204.161 153.313 169.295 1.00 304.54 ? 660 THR B C   1 
ATOM 2292 O O   . THR A 1 351 ? 204.109 152.195 168.774 1.00 304.54 ? 660 THR B O   1 
ATOM 2293 C CB  . THR A 1 351 ? 204.722 153.754 171.722 1.00 304.54 ? 660 THR B CB  1 
ATOM 2294 O OG1 . THR A 1 351 ? 205.815 153.648 172.649 1.00 304.54 ? 660 THR B OG1 1 
ATOM 2295 C CG2 . THR A 1 351 ? 203.693 152.666 172.006 1.00 304.54 ? 660 THR B CG2 1 
ATOM 2296 N N   . VAL A 1 352 ? 203.291 154.274 168.980 1.00 292.55 ? 661 VAL B N   1 
ATOM 2297 C CA  . VAL A 1 352 ? 202.205 153.996 168.048 1.00 292.55 ? 661 VAL B CA  1 
ATOM 2298 C C   . VAL A 1 352 ? 202.702 153.791 166.628 1.00 292.55 ? 661 VAL B C   1 
ATOM 2299 O O   . VAL A 1 352 ? 201.980 153.212 165.807 1.00 292.55 ? 661 VAL B O   1 
ATOM 2300 C CB  . VAL A 1 352 ? 201.156 155.125 168.074 1.00 292.55 ? 661 VAL B CB  1 
ATOM 2301 C CG1 . VAL A 1 352 ? 200.556 155.239 169.455 1.00 292.55 ? 661 VAL B CG1 1 
ATOM 2302 C CG2 . VAL A 1 352 ? 201.784 156.427 167.639 1.00 292.55 ? 661 VAL B CG2 1 
ATOM 2303 N N   . GLU A 1 353 ? 203.914 154.254 166.321 1.00 334.34 ? 662 GLU B N   1 
ATOM 2304 C CA  . GLU A 1 353 ? 204.557 154.023 165.036 1.00 334.34 ? 662 GLU B CA  1 
ATOM 2305 C C   . GLU A 1 353 ? 205.322 152.714 164.978 1.00 334.34 ? 662 GLU B C   1 
ATOM 2306 O O   . GLU A 1 353 ? 205.461 152.139 163.894 1.00 334.34 ? 662 GLU B O   1 
ATOM 2307 C CB  . GLU A 1 353 ? 205.530 155.163 164.708 1.00 334.34 ? 662 GLU B CB  1 
ATOM 2308 C CG  . GLU A 1 353 ? 205.740 155.390 163.216 1.00 334.34 ? 662 GLU B CG  1 
ATOM 2309 C CD  . GLU A 1 353 ? 206.916 154.595 162.663 1.00 334.34 ? 662 GLU B CD  1 
ATOM 2310 O OE1 . GLU A 1 353 ? 207.749 154.106 163.461 1.00 334.34 ? 662 GLU B OE1 1 
ATOM 2311 O OE2 . GLU A 1 353 ? 206.998 154.449 161.426 1.00 334.34 ? 662 GLU B OE2 1 
ATOM 2312 N N   . GLN A 1 354 ? 205.818 152.228 166.116 1.00 338.75 ? 663 GLN B N   1 
ATOM 2313 C CA  . GLN A 1 354 ? 206.720 151.086 166.095 1.00 338.75 ? 663 GLN B CA  1 
ATOM 2314 C C   . GLN A 1 354 ? 206.004 149.784 166.444 1.00 338.75 ? 663 GLN B C   1 
ATOM 2315 O O   . GLN A 1 354 ? 206.325 148.735 165.875 1.00 338.75 ? 663 GLN B O   1 
ATOM 2316 C CB  . GLN A 1 354 ? 207.890 151.325 167.059 1.00 338.75 ? 663 GLN B CB  1 
ATOM 2317 C CG  . GLN A 1 354 ? 208.943 150.233 167.050 1.00 338.75 ? 663 GLN B CG  1 
ATOM 2318 C CD  . GLN A 1 354 ? 209.929 150.396 165.901 1.00 338.75 ? 663 GLN B CD  1 
ATOM 2319 O OE1 . GLN A 1 354 ? 209.583 150.923 164.842 1.00 338.75 ? 663 GLN B OE1 1 
ATOM 2320 N NE2 . GLN A 1 354 ? 211.145 149.900 166.087 1.00 338.75 ? 663 GLN B NE2 1 
ATOM 2321 N N   . LEU A 1 355 ? 205.024 149.830 167.353 1.00 320.05 ? 664 LEU B N   1 
ATOM 2322 C CA  . LEU A 1 355 ? 204.332 148.610 167.765 1.00 320.05 ? 664 LEU B CA  1 
ATOM 2323 C C   . LEU A 1 355 ? 203.399 148.076 166.682 1.00 320.05 ? 664 LEU B C   1 
ATOM 2324 O O   . LEU A 1 355 ? 202.885 146.959 166.817 1.00 320.05 ? 664 LEU B O   1 
ATOM 2325 C CB  . LEU A 1 355 ? 203.561 148.847 169.070 1.00 320.05 ? 664 LEU B CB  1 
ATOM 2326 C CG  . LEU A 1 355 ? 204.421 148.852 170.345 1.00 320.05 ? 664 LEU B CG  1 
ATOM 2327 C CD1 . LEU A 1 355 ? 205.319 150.091 170.478 1.00 320.05 ? 664 LEU B CD1 1 
ATOM 2328 C CD2 . LEU A 1 355 ? 203.533 148.693 171.581 1.00 320.05 ? 664 LEU B CD2 1 
ATOM 2329 N N   . VAL A 1 356 ? 203.171 148.843 165.612 1.00 349.88 ? 665 VAL B N   1 
ATOM 2330 C CA  . VAL A 1 356 ? 202.354 148.362 164.500 1.00 349.88 ? 665 VAL B CA  1 
ATOM 2331 C C   . VAL A 1 356 ? 203.011 147.154 163.839 1.00 349.88 ? 665 VAL B C   1 
ATOM 2332 O O   . VAL A 1 356 ? 202.360 146.135 163.578 1.00 349.88 ? 665 VAL B O   1 
ATOM 2333 C CB  . VAL A 1 356 ? 202.104 149.501 163.497 1.00 349.88 ? 665 VAL B CB  1 
ATOM 2334 C CG1 . VAL A 1 356 ? 201.384 148.979 162.271 1.00 349.88 ? 665 VAL B CG1 1 
ATOM 2335 C CG2 . VAL A 1 356 ? 201.300 150.609 164.161 1.00 349.88 ? 665 VAL B CG2 1 
ATOM 2336 N N   . GLN A 1 357 ? 204.315 147.241 163.574 1.00 351.15 ? 666 GLN B N   1 
ATOM 2337 C CA  . GLN A 1 357 ? 205.056 146.115 163.020 1.00 351.15 ? 666 GLN B CA  1 
ATOM 2338 C C   . GLN A 1 357 ? 205.796 145.315 164.085 1.00 351.15 ? 666 GLN B C   1 
ATOM 2339 O O   . GLN A 1 357 ? 206.102 144.138 163.859 1.00 351.15 ? 666 GLN B O   1 
ATOM 2340 C CB  . GLN A 1 357 ? 206.055 146.609 161.967 1.00 351.15 ? 666 GLN B CB  1 
ATOM 2341 C CG  . GLN A 1 357 ? 207.174 147.463 162.533 1.00 351.15 ? 666 GLN B CG  1 
ATOM 2342 C CD  . GLN A 1 357 ? 207.044 148.928 162.172 1.00 351.15 ? 666 GLN B CD  1 
ATOM 2343 O OE1 . GLN A 1 357 ? 205.987 149.386 161.734 1.00 351.15 ? 666 GLN B OE1 1 
ATOM 2344 N NE2 . GLN A 1 357 ? 208.127 149.673 162.347 1.00 351.15 ? 666 GLN B NE2 1 
ATOM 2345 N N   . GLN A 1 358 ? 206.082 145.926 165.239 1.00 328.56 ? 667 GLN B N   1 
ATOM 2346 C CA  . GLN A 1 358 ? 206.767 145.224 166.319 1.00 328.56 ? 667 GLN B CA  1 
ATOM 2347 C C   . GLN A 1 358 ? 205.927 144.071 166.853 1.00 328.56 ? 667 GLN B C   1 
ATOM 2348 O O   . GLN A 1 358 ? 206.449 142.979 167.106 1.00 328.56 ? 667 GLN B O   1 
ATOM 2349 C CB  . GLN A 1 358 ? 207.099 146.211 167.439 1.00 328.56 ? 667 GLN B CB  1 
ATOM 2350 C CG  . GLN A 1 358 ? 208.005 145.663 168.522 1.00 328.56 ? 667 GLN B CG  1 
ATOM 2351 C CD  . GLN A 1 358 ? 209.424 145.461 168.043 1.00 328.56 ? 667 GLN B CD  1 
ATOM 2352 O OE1 . GLN A 1 358 ? 209.998 146.328 167.385 1.00 328.56 ? 667 GLN B OE1 1 
ATOM 2353 N NE2 . GLN A 1 358 ? 210.003 144.314 168.375 1.00 328.56 ? 667 GLN B NE2 1 
ATOM 2354 N N   . TYR A 1 359 ? 204.627 144.297 167.030 1.00 312.43 ? 668 TYR B N   1 
ATOM 2355 C CA  . TYR A 1 359 ? 203.691 143.306 167.558 1.00 312.43 ? 668 TYR B CA  1 
ATOM 2356 C C   . TYR A 1 359 ? 202.628 143.008 166.509 1.00 312.43 ? 668 TYR B C   1 
ATOM 2357 O O   . TYR A 1 359 ? 201.655 143.768 166.368 1.00 312.43 ? 668 TYR B O   1 
ATOM 2358 C CB  . TYR A 1 359 ? 203.063 143.801 168.856 1.00 312.43 ? 668 TYR B CB  1 
ATOM 2359 C CG  . TYR A 1 359 ? 204.070 144.030 169.957 1.00 312.43 ? 668 TYR B CG  1 
ATOM 2360 C CD1 . TYR A 1 359 ? 205.235 143.272 170.021 1.00 312.43 ? 668 TYR B CD1 1 
ATOM 2361 C CD2 . TYR A 1 359 ? 203.878 145.022 170.910 1.00 312.43 ? 668 TYR B CD2 1 
ATOM 2362 C CE1 . TYR A 1 359 ? 206.166 143.475 171.019 1.00 312.43 ? 668 TYR B CE1 1 
ATOM 2363 C CE2 . TYR A 1 359 ? 204.808 145.239 171.912 1.00 312.43 ? 668 TYR B CE2 1 
ATOM 2364 C CZ  . TYR A 1 359 ? 205.949 144.460 171.961 1.00 312.43 ? 668 TYR B CZ  1 
ATOM 2365 N N   . PRO A 1 360 ? 202.764 141.916 165.762 1.00 319.43 ? 669 PRO B N   1 
ATOM 2366 C CA  . PRO A 1 360 ? 201.719 141.521 164.811 1.00 319.43 ? 669 PRO B CA  1 
ATOM 2367 C C   . PRO A 1 360 ? 200.457 140.984 165.463 1.00 319.43 ? 669 PRO B C   1 
ATOM 2368 O O   . PRO A 1 360 ? 199.546 140.551 164.751 1.00 319.43 ? 669 PRO B O   1 
ATOM 2369 C CB  . PRO A 1 360 ? 202.413 140.429 163.983 1.00 319.43 ? 669 PRO B CB  1 
ATOM 2370 C CG  . PRO A 1 360 ? 203.400 139.827 164.914 1.00 319.43 ? 669 PRO B CG  1 
ATOM 2371 C CD  . PRO A 1 360 ? 203.857 140.930 165.834 1.00 319.43 ? 669 PRO B CD  1 
ATOM 2372 N N   . HIS A 1 361 ? 200.387 141.007 166.791 1.00 292.93 ? 670 HIS B N   1 
ATOM 2373 C CA  . HIS A 1 361 ? 199.228 140.554 167.540 1.00 292.93 ? 670 HIS B CA  1 
ATOM 2374 C C   . HIS A 1 361 ? 198.355 141.708 168.018 1.00 292.93 ? 670 HIS B C   1 
ATOM 2375 O O   . HIS A 1 361 ? 197.388 141.481 168.750 1.00 292.93 ? 670 HIS B O   1 
ATOM 2376 C CB  . HIS A 1 361 ? 199.690 139.699 168.716 1.00 292.93 ? 670 HIS B CB  1 
ATOM 2377 C CG  . HIS A 1 361 ? 200.908 140.236 169.399 1.00 292.93 ? 670 HIS B CG  1 
ATOM 2378 N ND1 . HIS A 1 361 ? 200.843 141.114 170.459 1.00 292.93 ? 670 HIS B ND1 1 
ATOM 2379 C CD2 . HIS A 1 361 ? 202.224 140.033 169.157 1.00 292.93 ? 670 HIS B CD2 1 
ATOM 2380 C CE1 . HIS A 1 361 ? 202.067 141.416 170.852 1.00 292.93 ? 670 HIS B CE1 1 
ATOM 2381 N NE2 . HIS A 1 361 ? 202.924 140.776 170.075 1.00 292.93 ? 670 HIS B NE2 1 
ATOM 2382 N N   . ILE A 1 362 ? 198.662 142.934 167.603 1.00 292.07 ? 671 ILE B N   1 
ATOM 2383 C CA  . ILE A 1 362 ? 197.867 144.112 167.935 1.00 292.07 ? 671 ILE B CA  1 
ATOM 2384 C C   . ILE A 1 362 ? 197.365 144.727 166.634 1.00 292.07 ? 671 ILE B C   1 
ATOM 2385 O O   . ILE A 1 362 ? 198.161 145.036 165.740 1.00 292.07 ? 671 ILE B O   1 
ATOM 2386 C CB  . ILE A 1 362 ? 198.679 145.132 168.755 1.00 292.07 ? 671 ILE B CB  1 
ATOM 2387 C CG1 . ILE A 1 362 ? 199.397 144.444 169.918 1.00 292.07 ? 671 ILE B CG1 1 
ATOM 2388 C CG2 . ILE A 1 362 ? 197.781 146.247 169.255 1.00 292.07 ? 671 ILE B CG2 1 
ATOM 2389 C CD1 . ILE A 1 362 ? 200.333 145.355 170.679 1.00 292.07 ? 671 ILE B CD1 1 
ATOM 2390 N N   . THR A 1 363 ? 196.044 144.907 166.532 1.00 325.32 ? 672 THR B N   1 
ATOM 2391 C CA  . THR A 1 363 ? 195.411 145.382 165.305 1.00 325.32 ? 672 THR B CA  1 
ATOM 2392 C C   . THR A 1 363 ? 195.055 146.862 165.327 1.00 325.32 ? 672 THR B C   1 
ATOM 2393 O O   . THR A 1 363 ? 195.018 147.485 164.259 1.00 325.32 ? 672 THR B O   1 
ATOM 2394 C CB  . THR A 1 363 ? 194.129 144.587 165.018 1.00 325.32 ? 672 THR B CB  1 
ATOM 2395 O OG1 . THR A 1 363 ? 193.226 144.710 166.125 1.00 325.32 ? 672 THR B OG1 1 
ATOM 2396 C CG2 . THR A 1 363 ? 194.446 143.117 164.788 1.00 325.32 ? 672 THR B CG2 1 
ATOM 2397 N N   . PHE A 1 364 ? 194.776 147.422 166.506 1.00 293.35 ? 673 PHE B N   1 
ATOM 2398 C CA  . PHE A 1 364 ? 194.323 148.798 166.692 1.00 293.35 ? 673 PHE B CA  1 
ATOM 2399 C C   . PHE A 1 364 ? 192.945 149.011 166.068 1.00 293.35 ? 673 PHE B C   1 
ATOM 2400 O O   . PHE A 1 364 ? 192.559 148.308 165.128 1.00 293.35 ? 673 PHE B O   1 
ATOM 2401 C CB  . PHE A 1 364 ? 195.341 149.786 166.112 1.00 293.35 ? 673 PHE B CB  1 
ATOM 2402 C CG  . PHE A 1 364 ? 196.613 149.887 166.910 1.00 293.35 ? 673 PHE B CG  1 
ATOM 2403 C CD1 . PHE A 1 364 ? 196.745 150.819 167.926 1.00 293.35 ? 673 PHE B CD1 1 
ATOM 2404 C CD2 . PHE A 1 364 ? 197.680 149.041 166.644 1.00 293.35 ? 673 PHE B CD2 1 
ATOM 2405 C CE1 . PHE A 1 364 ? 197.917 150.905 168.659 1.00 293.35 ? 673 PHE B CE1 1 
ATOM 2406 C CE2 . PHE A 1 364 ? 198.853 149.124 167.373 1.00 293.35 ? 673 PHE B CE2 1 
ATOM 2407 C CZ  . PHE A 1 364 ? 198.971 150.057 168.381 1.00 293.35 ? 673 PHE B CZ  1 
ATOM 2408 N N   . SER A 1 365 ? 192.184 149.976 166.592 1.00 243.46 ? 674 SER B N   1 
ATOM 2409 C CA  . SER A 1 365 ? 190.853 150.251 166.063 1.00 243.46 ? 674 SER B CA  1 
ATOM 2410 C C   . SER A 1 365 ? 190.525 151.738 166.093 1.00 243.46 ? 674 SER B C   1 
ATOM 2411 O O   . SER A 1 365 ? 189.345 152.102 166.166 1.00 243.46 ? 674 SER B O   1 
ATOM 2412 C CB  . SER A 1 365 ? 189.778 149.470 166.827 1.00 243.46 ? 674 SER B CB  1 
ATOM 2413 O OG  . SER A 1 365 ? 188.482 149.789 166.350 1.00 243.46 ? 674 SER B OG  1 
ATOM 2414 N N   . THR A 1 366 ? 191.534 152.602 166.050 1.00 198.25 ? 675 THR B N   1 
ATOM 2415 C CA  . THR A 1 366 ? 191.300 154.033 165.992 1.00 198.25 ? 675 THR B CA  1 
ATOM 2416 C C   . THR A 1 366 ? 190.528 154.392 164.727 1.00 198.25 ? 675 THR B C   1 
ATOM 2417 O O   . THR A 1 366 ? 190.397 153.590 163.798 1.00 198.25 ? 675 THR B O   1 
ATOM 2418 C CB  . THR A 1 366 ? 192.631 154.784 166.042 1.00 198.25 ? 675 THR B CB  1 
ATOM 2419 O OG1 . THR A 1 366 ? 192.396 156.197 166.134 1.00 198.25 ? 675 THR B OG1 1 
ATOM 2420 C CG2 . THR A 1 366 ? 193.471 154.464 164.822 1.00 198.25 ? 675 THR B CG2 1 
ATOM 2421 N N   . VAL A 1 367 ? 190.001 155.619 164.700 1.00 176.40 ? 676 VAL B N   1 
ATOM 2422 C CA  . VAL A 1 367 ? 189.287 156.073 163.511 1.00 176.40 ? 676 VAL B CA  1 
ATOM 2423 C C   . VAL A 1 367 ? 190.188 155.975 162.290 1.00 176.40 ? 676 VAL B C   1 
ATOM 2424 O O   . VAL A 1 367 ? 189.706 155.840 161.159 1.00 176.40 ? 676 VAL B O   1 
ATOM 2425 C CB  . VAL A 1 367 ? 188.746 157.504 163.701 1.00 176.40 ? 676 VAL B CB  1 
ATOM 2426 C CG1 . VAL A 1 367 ? 187.599 157.513 164.694 1.00 176.40 ? 676 VAL B CG1 1 
ATOM 2427 C CG2 . VAL A 1 367 ? 189.854 158.436 164.162 1.00 176.40 ? 676 VAL B CG2 1 
ATOM 2428 N N   . LEU A 1 368 ? 191.507 156.030 162.494 1.00 170.94 ? 677 LEU B N   1 
ATOM 2429 C CA  . LEU A 1 368 ? 192.447 155.791 161.409 1.00 170.94 ? 677 LEU B CA  1 
ATOM 2430 C C   . LEU A 1 368 ? 192.439 154.343 160.941 1.00 170.94 ? 677 LEU B C   1 
ATOM 2431 O O   . LEU A 1 368 ? 192.795 154.077 159.791 1.00 170.94 ? 677 LEU B O   1 
ATOM 2432 C CB  . LEU A 1 368 ? 193.859 156.188 161.842 1.00 170.94 ? 677 LEU B CB  1 
ATOM 2433 C CG  . LEU A 1 368 ? 194.981 156.069 160.812 1.00 170.94 ? 677 LEU B CG  1 
ATOM 2434 C CD1 . LEU A 1 368 ? 194.720 156.996 159.640 1.00 170.94 ? 677 LEU B CD1 1 
ATOM 2435 C CD2 . LEU A 1 368 ? 196.335 156.355 161.448 1.00 170.94 ? 677 LEU B CD2 1 
ATOM 2436 N N   . GLN A 1 369 ? 192.033 153.402 161.792 1.00 197.93 ? 678 GLN B N   1 
ATOM 2437 C CA  . GLN A 1 369 ? 192.034 152.001 161.398 1.00 197.93 ? 678 GLN B CA  1 
ATOM 2438 C C   . GLN A 1 369 ? 190.720 151.535 160.804 1.00 197.93 ? 678 GLN B C   1 
ATOM 2439 O O   . GLN A 1 369 ? 190.738 150.759 159.846 1.00 197.93 ? 678 GLN B O   1 
ATOM 2440 C CB  . GLN A 1 369 ? 192.380 151.096 162.588 1.00 197.93 ? 678 GLN B CB  1 
ATOM 2441 C CG  . GLN A 1 369 ? 192.481 149.602 162.234 1.00 197.93 ? 678 GLN B CG  1 
ATOM 2442 C CD  . GLN A 1 369 ? 191.147 148.880 162.253 1.00 197.93 ? 678 GLN B CD  1 
ATOM 2443 O OE1 . GLN A 1 369 ? 190.202 149.316 162.908 1.00 197.93 ? 678 GLN B OE1 1 
ATOM 2444 N NE2 . GLN A 1 369 ? 191.064 147.775 161.525 1.00 197.93 ? 678 GLN B NE2 1 
ATOM 2445 N N   . ASP A 1 370 ? 189.581 151.991 161.321 1.00 155.34 ? 679 ASP B N   1 
ATOM 2446 C CA  . ASP A 1 370 ? 188.329 151.475 160.788 1.00 155.34 ? 679 ASP B CA  1 
ATOM 2447 C C   . ASP A 1 370 ? 187.993 152.190 159.490 1.00 155.34 ? 679 ASP B C   1 
ATOM 2448 O O   . ASP A 1 370 ? 186.869 152.664 159.297 1.00 155.34 ? 679 ASP B O   1 
ATOM 2449 C CB  . ASP A 1 370 ? 187.196 151.644 161.799 1.00 155.34 ? 679 ASP B CB  1 
ATOM 2450 C CG  . ASP A 1 370 ? 187.019 153.078 162.231 1.00 155.34 ? 679 ASP B CG  1 
ATOM 2451 O OD1 . ASP A 1 370 ? 187.827 153.926 161.808 1.00 155.34 ? 679 ASP B OD1 1 
ATOM 2452 O OD2 . ASP A 1 370 ? 186.069 153.360 162.987 1.00 155.34 ? 679 ASP B OD2 1 
ATOM 2453 N N   . CYS A 1 371 ? 188.965 152.264 158.609 1.00 175.39 ? 680 CYS B N   1 
ATOM 2454 C CA  . CYS A 1 371 ? 188.818 152.713 157.235 1.00 175.39 ? 680 CYS B CA  1 
ATOM 2455 C C   . CYS A 1 371 ? 189.474 151.762 156.249 1.00 175.39 ? 680 CYS B C   1 
ATOM 2456 O O   . CYS A 1 371 ? 188.902 151.495 155.190 1.00 175.39 ? 680 CYS B O   1 
ATOM 2457 C CB  . CYS A 1 371 ? 189.407 154.116 157.065 1.00 175.39 ? 680 CYS B CB  1 
ATOM 2458 S SG  . CYS A 1 371 ? 191.205 154.165 157.151 1.00 175.39 ? 680 CYS B SG  1 
ATOM 2459 N N   . LYS A 1 372 ? 190.656 151.232 156.576 1.00 182.11 ? 681 LYS B N   1 
ATOM 2460 C CA  . LYS A 1 372 ? 191.261 150.235 155.703 1.00 182.11 ? 681 LYS B CA  1 
ATOM 2461 C C   . LYS A 1 372 ? 190.414 148.980 155.650 1.00 182.11 ? 681 LYS B C   1 
ATOM 2462 O O   . LYS A 1 372 ? 190.137 148.452 154.570 1.00 182.11 ? 681 LYS B O   1 
ATOM 2463 C CB  . LYS A 1 372 ? 192.666 149.872 156.168 1.00 182.11 ? 681 LYS B CB  1 
ATOM 2464 C CG  . LYS A 1 372 ? 193.562 149.483 155.009 1.00 182.11 ? 681 LYS B CG  1 
ATOM 2465 C CD  . LYS A 1 372 ? 194.792 148.741 155.475 1.00 182.11 ? 681 LYS B CD  1 
ATOM 2466 C CE  . LYS A 1 372 ? 194.418 147.344 155.952 1.00 182.11 ? 681 LYS B CE  1 
ATOM 2467 N NZ  . LYS A 1 372 ? 193.784 146.535 154.873 1.00 182.11 ? 681 LYS B NZ  1 
ATOM 2468 N N   . ARG A 1 373 ? 189.989 148.494 156.814 1.00 192.41 ? 682 ARG B N   1 
ATOM 2469 C CA  . ARG A 1 373 ? 189.162 147.298 156.858 1.00 192.41 ? 682 ARG B CA  1 
ATOM 2470 C C   . ARG A 1 373 ? 187.870 147.503 156.083 1.00 192.41 ? 682 ARG B C   1 
ATOM 2471 O O   . ARG A 1 373 ? 187.429 146.613 155.347 1.00 192.41 ? 682 ARG B O   1 
ATOM 2472 C CB  . ARG A 1 373 ? 188.884 146.933 158.315 1.00 192.41 ? 682 ARG B CB  1 
ATOM 2473 C CG  . ARG A 1 373 ? 187.534 146.312 158.571 1.00 192.41 ? 682 ARG B CG  1 
ATOM 2474 C CD  . ARG A 1 373 ? 187.382 145.984 160.042 1.00 192.41 ? 682 ARG B CD  1 
ATOM 2475 N NE  . ARG A 1 373 ? 186.753 147.078 160.771 1.00 192.41 ? 682 ARG B NE  1 
ATOM 2476 C CZ  . ARG A 1 373 ? 185.926 147.960 160.226 1.00 192.41 ? 682 ARG B CZ  1 
ATOM 2477 N N   . THR A 1 374 ? 187.265 148.682 156.217 1.00 183.39 ? 683 THR B N   1 
ATOM 2478 C CA  . THR A 1 374 ? 186.039 148.971 155.483 1.00 183.39 ? 683 THR B CA  1 
ATOM 2479 C C   . THR A 1 374 ? 186.296 149.054 153.983 1.00 183.39 ? 683 THR B C   1 
ATOM 2480 O O   . THR A 1 374 ? 185.447 148.656 153.177 1.00 183.39 ? 683 THR B O   1 
ATOM 2481 C CB  . THR A 1 374 ? 185.430 150.270 155.998 1.00 183.39 ? 683 THR B CB  1 
ATOM 2482 O OG1 . THR A 1 374 ? 186.347 151.347 155.776 1.00 183.39 ? 683 THR B OG1 1 
ATOM 2483 C CG2 . THR A 1 374 ? 185.167 150.155 157.487 1.00 183.39 ? 683 THR B CG2 1 
ATOM 2484 N N   . LEU A 1 375 ? 187.455 149.588 153.588 1.00 174.37 ? 684 LEU B N   1 
ATOM 2485 C CA  . LEU A 1 375 ? 187.801 149.642 152.171 1.00 174.37 ? 684 LEU B CA  1 
ATOM 2486 C C   . LEU A 1 375 ? 188.022 148.246 151.604 1.00 174.37 ? 684 LEU B C   1 
ATOM 2487 O O   . LEU A 1 375 ? 187.709 147.985 150.435 1.00 174.37 ? 684 LEU B O   1 
ATOM 2488 C CB  . LEU A 1 375 ? 189.045 150.506 151.960 1.00 174.37 ? 684 LEU B CB  1 
ATOM 2489 C CG  . LEU A 1 375 ? 188.825 151.997 151.686 1.00 174.37 ? 684 LEU B CG  1 
ATOM 2490 C CD1 . LEU A 1 375 ? 190.103 152.627 151.154 1.00 174.37 ? 684 LEU B CD1 1 
ATOM 2491 C CD2 . LEU A 1 375 ? 187.662 152.227 150.723 1.00 174.37 ? 684 LEU B CD2 1 
ATOM 2492 N N   . GLU A 1 376 ? 188.577 147.342 152.412 1.00 197.57 ? 685 GLU B N   1 
ATOM 2493 C CA  . GLU A 1 376 ? 188.804 145.980 151.944 1.00 197.57 ? 685 GLU B CA  1 
ATOM 2494 C C   . GLU A 1 376 ? 187.494 145.300 151.569 1.00 197.57 ? 685 GLU B C   1 
ATOM 2495 O O   . GLU A 1 376 ? 187.411 144.634 150.532 1.00 197.57 ? 685 GLU B O   1 
ATOM 2496 C CB  . GLU A 1 376 ? 189.544 145.169 153.010 1.00 197.57 ? 685 GLU B CB  1 
ATOM 2497 C CG  . GLU A 1 376 ? 190.898 145.731 153.426 1.00 197.57 ? 685 GLU B CG  1 
ATOM 2498 C CD  . GLU A 1 376 ? 191.660 146.364 152.280 1.00 197.57 ? 685 GLU B CD  1 
ATOM 2499 O OE1 . GLU A 1 376 ? 192.014 145.640 151.326 1.00 197.57 ? 685 GLU B OE1 1 
ATOM 2500 O OE2 . GLU A 1 376 ? 191.908 147.589 152.330 1.00 197.57 ? 685 GLU B OE2 1 
ATOM 2501 N N   . ARG A 1 377 ? 186.458 145.462 152.388 1.00 226.33 ? 686 ARG B N   1 
ATOM 2502 C CA  . ARG A 1 377 ? 185.157 144.869 152.087 1.00 226.33 ? 686 ARG B CA  1 
ATOM 2503 C C   . ARG A 1 377 ? 184.405 145.694 151.049 1.00 226.33 ? 686 ARG B C   1 
ATOM 2504 O O   . ARG A 1 377 ? 183.263 145.386 150.708 1.00 226.33 ? 686 ARG B O   1 
ATOM 2505 C CB  . ARG A 1 377 ? 184.307 144.732 153.353 1.00 226.33 ? 686 ARG B CB  1 
ATOM 2506 C CG  . ARG A 1 377 ? 183.662 146.027 153.817 1.00 226.33 ? 686 ARG B CG  1 
ATOM 2507 C CD  . ARG A 1 377 ? 182.559 145.770 154.835 1.00 226.33 ? 686 ARG B CD  1 
ATOM 2508 N NE  . ARG A 1 377 ? 182.886 144.692 155.760 1.00 226.33 ? 686 ARG B NE  1 
ATOM 2509 C CZ  . ARG A 1 377 ? 182.028 143.765 156.162 1.00 226.33 ? 686 ARG B CZ  1 
ATOM 2510 N N   . SER B 2 11  ? 193.245 160.949 160.207 1.00 93.00  ? 17  SER C N   1 
ATOM 2511 C CA  . SER B 2 11  ? 193.768 162.225 159.737 1.00 93.00  ? 17  SER C CA  1 
ATOM 2512 C C   . SER B 2 11  ? 192.675 163.104 159.150 1.00 93.00  ? 17  SER C C   1 
ATOM 2513 O O   . SER B 2 11  ? 191.496 162.748 159.165 1.00 93.00  ? 17  SER C O   1 
ATOM 2514 C CB  . SER B 2 11  ? 194.864 162.007 158.696 1.00 93.00  ? 17  SER C CB  1 
ATOM 2515 O OG  . SER B 2 11  ? 195.294 163.244 158.155 1.00 93.00  ? 17  SER C OG  1 
ATOM 2516 N N   . THR B 2 12  ? 193.087 164.261 158.631 1.00 86.82  ? 18  THR C N   1 
ATOM 2517 C CA  . THR B 2 12  ? 192.130 165.220 158.094 1.00 86.82  ? 18  THR C CA  1 
ATOM 2518 C C   . THR B 2 12  ? 191.396 164.650 156.886 1.00 86.82  ? 18  THR C C   1 
ATOM 2519 O O   . THR B 2 12  ? 190.160 164.628 156.848 1.00 86.82  ? 18  THR C O   1 
ATOM 2520 C CB  . THR B 2 12  ? 192.851 166.515 157.727 1.00 86.82  ? 18  THR C CB  1 
ATOM 2521 O OG1 . THR B 2 12  ? 193.766 166.262 156.653 1.00 86.82  ? 18  THR C OG1 1 
ATOM 2522 C CG2 . THR B 2 12  ? 193.623 167.043 158.924 1.00 86.82  ? 18  THR C CG2 1 
ATOM 2523 N N   . ASN B 2 13  ? 192.144 164.165 155.891 1.00 85.65  ? 19  ASN C N   1 
ATOM 2524 C CA  . ASN B 2 13  ? 191.492 163.527 154.753 1.00 85.65  ? 19  ASN C CA  1 
ATOM 2525 C C   . ASN B 2 13  ? 190.781 162.254 155.183 1.00 85.65  ? 19  ASN C C   1 
ATOM 2526 O O   . ASN B 2 13  ? 189.771 161.878 154.585 1.00 85.65  ? 19  ASN C O   1 
ATOM 2527 C CB  . ASN B 2 13  ? 192.499 163.225 153.644 1.00 85.65  ? 19  ASN C CB  1 
ATOM 2528 C CG  . ASN B 2 13  ? 193.374 162.038 153.963 1.00 85.65  ? 19  ASN C CG  1 
ATOM 2529 O OD1 . ASN B 2 13  ? 193.779 161.841 155.107 1.00 85.65  ? 19  ASN C OD1 1 
ATOM 2530 N ND2 . ASN B 2 13  ? 193.653 161.223 152.952 1.00 85.65  ? 19  ASN C ND2 1 
ATOM 2531 N N   . VAL B 2 14  ? 191.288 161.581 156.217 1.00 83.12  ? 20  VAL C N   1 
ATOM 2532 C CA  . VAL B 2 14  ? 190.560 160.454 156.787 1.00 83.12  ? 20  VAL C CA  1 
ATOM 2533 C C   . VAL B 2 14  ? 189.230 160.925 157.349 1.00 83.12  ? 20  VAL C C   1 
ATOM 2534 O O   . VAL B 2 14  ? 188.194 160.276 157.163 1.00 83.12  ? 20  VAL C O   1 
ATOM 2535 C CB  . VAL B 2 14  ? 191.405 159.758 157.867 1.00 83.12  ? 20  VAL C CB  1 
ATOM 2536 C CG1 . VAL B 2 14  ? 190.602 158.655 158.528 1.00 83.12  ? 20  VAL C CG1 1 
ATOM 2537 C CG2 . VAL B 2 14  ? 192.685 159.215 157.267 1.00 83.12  ? 20  VAL C CG2 1 
ATOM 2538 N N   . LEU B 2 15  ? 189.240 162.063 158.042 1.00 81.42  ? 21  LEU C N   1 
ATOM 2539 C CA  . LEU B 2 15  ? 187.998 162.619 158.556 1.00 81.42  ? 21  LEU C CA  1 
ATOM 2540 C C   . LEU B 2 15  ? 187.021 162.904 157.427 1.00 81.42  ? 21  LEU C C   1 
ATOM 2541 O O   . LEU B 2 15  ? 185.840 162.556 157.517 1.00 81.42  ? 21  LEU C O   1 
ATOM 2542 C CB  . LEU B 2 15  ? 188.284 163.893 159.348 1.00 81.42  ? 21  LEU C CB  1 
ATOM 2543 C CG  . LEU B 2 15  ? 187.072 164.570 159.987 1.00 81.42  ? 21  LEU C CG  1 
ATOM 2544 C CD1 . LEU B 2 15  ? 186.759 163.954 161.342 1.00 81.42  ? 21  LEU C CD1 1 
ATOM 2545 C CD2 . LEU B 2 15  ? 187.294 166.072 160.106 1.00 81.42  ? 21  LEU C CD2 1 
ATOM 2546 N N   . LEU B 2 16  ? 187.499 163.514 156.343 1.00 80.51  ? 22  LEU C N   1 
ATOM 2547 C CA  . LEU B 2 16  ? 186.606 163.830 155.231 1.00 80.51  ? 22  LEU C CA  1 
ATOM 2548 C C   . LEU B 2 16  ? 186.093 162.571 154.543 1.00 80.51  ? 22  LEU C C   1 
ATOM 2549 O O   . LEU B 2 16  ? 184.928 162.514 154.132 1.00 80.51  ? 22  LEU C O   1 
ATOM 2550 C CB  . LEU B 2 16  ? 187.307 164.743 154.227 1.00 80.51  ? 22  LEU C CB  1 
ATOM 2551 C CG  . LEU B 2 16  ? 187.314 166.245 154.523 1.00 80.51  ? 22  LEU C CG  1 
ATOM 2552 C CD1 . LEU B 2 16  ? 185.889 166.774 154.504 1.00 80.51  ? 22  LEU C CD1 1 
ATOM 2553 C CD2 . LEU B 2 16  ? 187.988 166.578 155.840 1.00 80.51  ? 22  LEU C CD2 1 
ATOM 2554 N N   . SER B 2 17  ? 186.950 161.565 154.380 1.00 78.98  ? 23  SER C N   1 
ATOM 2555 C CA  . SER B 2 17  ? 186.513 160.326 153.751 1.00 78.98  ? 23  SER C CA  1 
ATOM 2556 C C   . SER B 2 17  ? 185.453 159.636 154.595 1.00 78.98  ? 23  SER C C   1 
ATOM 2557 O O   . SER B 2 17  ? 184.435 159.167 154.070 1.00 78.98  ? 23  SER C O   1 
ATOM 2558 C CB  . SER B 2 17  ? 187.709 159.406 153.527 1.00 78.98  ? 23  SER C CB  1 
ATOM 2559 O OG  . SER B 2 17  ? 187.297 158.173 152.970 1.00 78.98  ? 23  SER C OG  1 
ATOM 2560 N N   . LEU B 2 18  ? 185.668 159.579 155.911 1.00 83.56  ? 24  LEU C N   1 
ATOM 2561 C CA  . LEU B 2 18  ? 184.647 159.041 156.801 1.00 83.56  ? 24  LEU C CA  1 
ATOM 2562 C C   . LEU B 2 18  ? 183.378 159.869 156.715 1.00 83.56  ? 24  LEU C C   1 
ATOM 2563 O O   . LEU B 2 18  ? 182.267 159.333 156.773 1.00 83.56  ? 24  LEU C O   1 
ATOM 2564 C CB  . LEU B 2 18  ? 185.170 159.015 158.237 1.00 83.56  ? 24  LEU C CB  1 
ATOM 2565 C CG  . LEU B 2 18  ? 186.244 157.983 158.574 1.00 83.56  ? 24  LEU C CG  1 
ATOM 2566 C CD1 . LEU B 2 18  ? 187.110 158.470 159.726 1.00 83.56  ? 24  LEU C CD1 1 
ATOM 2567 C CD2 . LEU B 2 18  ? 185.594 156.657 158.912 1.00 83.56  ? 24  LEU C CD2 1 
ATOM 2568 N N   . ASN B 2 19  ? 183.531 161.181 156.560 1.00 86.56  ? 25  ASN C N   1 
ATOM 2569 C CA  . ASN B 2 19  ? 182.388 162.074 156.463 1.00 86.56  ? 25  ASN C CA  1 
ATOM 2570 C C   . ASN B 2 19  ? 181.536 161.731 155.251 1.00 86.56  ? 25  ASN C C   1 
ATOM 2571 O O   . ASN B 2 19  ? 180.309 161.608 155.341 1.00 86.56  ? 25  ASN C O   1 
ATOM 2572 C CB  . ASN B 2 19  ? 182.896 163.509 156.375 1.00 86.56  ? 25  ASN C CB  1 
ATOM 2573 C CG  . ASN B 2 19  ? 181.937 164.497 156.955 1.00 86.56  ? 25  ASN C CG  1 
ATOM 2574 O OD1 . ASN B 2 19  ? 180.897 164.784 156.378 1.00 86.56  ? 25  ASN C OD1 1 
ATOM 2575 N ND2 . ASN B 2 19  ? 182.293 165.053 158.100 1.00 86.56  ? 25  ASN C ND2 1 
ATOM 2576 N N   . ASP B 2 20  ? 182.182 161.568 154.099 1.00 87.90  ? 26  ASP C N   1 
ATOM 2577 C CA  . ASP B 2 20  ? 181.443 161.215 152.893 1.00 87.90  ? 26  ASP C CA  1 
ATOM 2578 C C   . ASP B 2 20  ? 180.811 159.839 153.029 1.00 87.90  ? 26  ASP C C   1 
ATOM 2579 O O   . ASP B 2 20  ? 179.640 159.644 152.682 1.00 87.90  ? 26  ASP C O   1 
ATOM 2580 C CB  . ASP B 2 20  ? 182.351 161.261 151.670 1.00 87.90  ? 26  ASP C CB  1 
ATOM 2581 C CG  . ASP B 2 20  ? 181.587 161.038 150.385 1.00 87.90  ? 26  ASP C CG  1 
ATOM 2582 O OD1 . ASP B 2 20  ? 180.870 161.965 149.956 1.00 87.90  ? 26  ASP C OD1 1 
ATOM 2583 O OD2 . ASP B 2 20  ? 181.690 159.933 149.813 1.00 87.90  ? 26  ASP C OD2 1 
ATOM 2584 N N   . GLN B 2 21  ? 181.573 158.870 153.540 1.00 85.27  ? 27  GLN C N   1 
ATOM 2585 C CA  . GLN B 2 21  ? 181.019 157.534 153.703 1.00 85.27  ? 27  GLN C CA  1 
ATOM 2586 C C   . GLN B 2 21  ? 179.805 157.553 154.618 1.00 85.27  ? 27  GLN C C   1 
ATOM 2587 O O   . GLN B 2 21  ? 178.869 156.769 154.422 1.00 85.27  ? 27  GLN C O   1 
ATOM 2588 C CB  . GLN B 2 21  ? 182.089 156.580 154.229 1.00 85.27  ? 27  GLN C CB  1 
ATOM 2589 C CG  . GLN B 2 21  ? 183.148 156.220 153.200 1.00 85.27  ? 27  GLN C CG  1 
ATOM 2590 C CD  . GLN B 2 21  ? 182.593 155.392 152.056 1.00 85.27  ? 27  GLN C CD  1 
ATOM 2591 O OE1 . GLN B 2 21  ? 181.641 154.630 152.232 1.00 85.27  ? 27  GLN C OE1 1 
ATOM 2592 N NE2 . GLN B 2 21  ? 183.188 155.535 150.877 1.00 85.27  ? 27  GLN C NE2 1 
ATOM 2593 N N   . ARG B 2 22  ? 179.792 158.447 155.608 1.00 81.27  ? 28  ARG C N   1 
ATOM 2594 C CA  . ARG B 2 22  ? 178.565 158.683 156.354 1.00 81.27  ? 28  ARG C CA  1 
ATOM 2595 C C   . ARG B 2 22  ? 177.487 159.224 155.433 1.00 81.27  ? 28  ARG C C   1 
ATOM 2596 O O   . ARG B 2 22  ? 176.356 158.723 155.415 1.00 81.27  ? 28  ARG C O   1 
ATOM 2597 C CB  . ARG B 2 22  ? 178.801 159.661 157.499 1.00 81.27  ? 28  ARG C CB  1 
ATOM 2598 C CG  . ARG B 2 22  ? 177.501 160.218 158.071 1.00 81.27  ? 28  ARG C CG  1 
ATOM 2599 C CD  . ARG B 2 22  ? 177.597 161.689 158.398 1.00 81.27  ? 28  ARG C CD  1 
ATOM 2600 N NE  . ARG B 2 22  ? 176.291 162.335 158.338 1.00 81.27  ? 28  ARG C NE  1 
ATOM 2601 C CZ  . ARG B 2 22  ? 175.150 161.748 158.668 1.00 81.27  ? 28  ARG C CZ  1 
ATOM 2602 N N   . LYS B 2 23  ? 177.825 160.238 154.643 1.00 77.51  ? 29  LYS C N   1 
ATOM 2603 C CA  . LYS B 2 23  ? 176.841 160.757 153.700 1.00 77.51  ? 29  LYS C CA  1 
ATOM 2604 C C   . LYS B 2 23  ? 176.842 159.984 152.401 1.00 77.51  ? 29  LYS C C   1 
ATOM 2605 O O   . LYS B 2 23  ? 176.740 160.563 151.320 1.00 77.51  ? 29  LYS C O   1 
ATOM 2606 C CB  . LYS B 2 23  ? 177.081 162.240 153.445 1.00 77.51  ? 29  LYS C CB  1 
ATOM 2607 C CG  . LYS B 2 23  ? 176.871 163.107 154.666 1.00 77.51  ? 29  LYS C CG  1 
ATOM 2608 C CD  . LYS B 2 23  ? 176.948 164.575 154.308 1.00 77.51  ? 29  LYS C CD  1 
ATOM 2609 C CE  . LYS B 2 23  ? 178.356 164.963 153.950 1.00 77.51  ? 29  LYS C CE  1 
ATOM 2610 N NZ  . LYS B 2 23  ? 179.214 164.858 155.147 1.00 77.51  ? 29  LYS C NZ  1 
ATOM 2611 N N   . LYS B 2 24  ? 176.903 158.660 152.509 1.00 93.52  ? 30  LYS C N   1 
ATOM 2612 C CA  . LYS B 2 24  ? 176.531 157.734 151.452 1.00 93.52  ? 30  LYS C CA  1 
ATOM 2613 C C   . LYS B 2 24  ? 175.408 156.796 151.865 1.00 93.52  ? 30  LYS C C   1 
ATOM 2614 O O   . LYS B 2 24  ? 174.871 156.089 151.004 1.00 93.52  ? 30  LYS C O   1 
ATOM 2615 C CB  . LYS B 2 24  ? 177.731 156.878 151.015 1.00 93.52  ? 30  LYS C CB  1 
ATOM 2616 C CG  . LYS B 2 24  ? 178.960 157.588 150.440 1.00 93.52  ? 30  LYS C CG  1 
ATOM 2617 C CD  . LYS B 2 24  ? 178.746 158.178 149.042 1.00 93.52  ? 30  LYS C CD  1 
ATOM 2618 C CE  . LYS B 2 24  ? 178.333 159.629 149.058 1.00 93.52  ? 30  LYS C CE  1 
ATOM 2619 N NZ  . LYS B 2 24  ? 178.239 160.202 147.692 1.00 93.52  ? 30  LYS C NZ  1 
ATOM 2620 N N   . ASP B 2 25  ? 175.040 156.770 153.149 1.00 104.85 ? 31  ASP C N   1 
ATOM 2621 C CA  . ASP B 2 25  ? 174.101 155.790 153.699 1.00 104.85 ? 31  ASP C CA  1 
ATOM 2622 C C   . ASP B 2 25  ? 174.570 154.357 153.466 1.00 104.85 ? 31  ASP C C   1 
ATOM 2623 O O   . ASP B 2 25  ? 173.758 153.444 153.308 1.00 104.85 ? 31  ASP C O   1 
ATOM 2624 C CB  . ASP B 2 25  ? 172.689 155.981 153.142 1.00 104.85 ? 31  ASP C CB  1 
ATOM 2625 C CG  . ASP B 2 25  ? 171.641 155.308 153.995 1.00 104.85 ? 31  ASP C CG  1 
ATOM 2626 O OD1 . ASP B 2 25  ? 171.849 155.214 155.221 1.00 104.85 ? 31  ASP C OD1 1 
ATOM 2627 O OD2 . ASP B 2 25  ? 170.622 154.852 153.439 1.00 104.85 ? 31  ASP C OD2 1 
ATOM 2628 N N   . VAL B 2 26  ? 175.881 154.140 153.459 1.00 102.47 ? 32  VAL C N   1 
ATOM 2629 C CA  . VAL B 2 26  ? 176.444 152.806 153.305 1.00 102.47 ? 32  VAL C CA  1 
ATOM 2630 C C   . VAL B 2 26  ? 177.559 152.639 154.322 1.00 102.47 ? 32  VAL C C   1 
ATOM 2631 O O   . VAL B 2 26  ? 178.297 153.586 154.617 1.00 102.47 ? 32  VAL C O   1 
ATOM 2632 C CB  . VAL B 2 26  ? 176.958 152.557 151.873 1.00 102.47 ? 32  VAL C CB  1 
ATOM 2633 C CG1 . VAL B 2 26  ? 178.260 153.304 151.620 1.00 102.47 ? 32  VAL C CG1 1 
ATOM 2634 C CG2 . VAL B 2 26  ? 177.128 151.069 151.628 1.00 102.47 ? 32  VAL C CG2 1 
ATOM 2635 N N   . LEU B 2 27  ? 177.664 151.430 154.877 1.00 99.69  ? 33  LEU C N   1 
ATOM 2636 C CA  . LEU B 2 27  ? 178.695 151.084 155.851 1.00 99.69  ? 33  LEU C CA  1 
ATOM 2637 C C   . LEU B 2 27  ? 178.599 152.004 157.076 1.00 99.69  ? 33  LEU C C   1 
ATOM 2638 O O   . LEU B 2 27  ? 179.472 152.819 157.374 1.00 99.69  ? 33  LEU C O   1 
ATOM 2639 C CB  . LEU B 2 27  ? 180.070 151.119 155.170 1.00 99.69  ? 33  LEU C CB  1 
ATOM 2640 C CG  . LEU B 2 27  ? 181.331 150.529 155.793 1.00 99.69  ? 33  LEU C CG  1 
ATOM 2641 C CD1 . LEU B 2 27  ? 182.221 150.048 154.667 1.00 99.69  ? 33  LEU C CD1 1 
ATOM 2642 C CD2 . LEU B 2 27  ? 182.072 151.544 156.635 1.00 99.69  ? 33  LEU C CD2 1 
ATOM 2643 N N   . CYS B 2 28  ? 177.465 151.872 157.756 1.00 95.72  ? 34  CYS C N   1 
ATOM 2644 C CA  . CYS B 2 28  ? 177.168 152.634 158.963 1.00 95.72  ? 34  CYS C CA  1 
ATOM 2645 C C   . CYS B 2 28  ? 176.880 151.654 160.089 1.00 95.72  ? 34  CYS C C   1 
ATOM 2646 O O   . CYS B 2 28  ? 176.034 150.767 159.940 1.00 95.72  ? 34  CYS C O   1 
ATOM 2647 C CB  . CYS B 2 28  ? 175.976 153.566 158.744 1.00 95.72  ? 34  CYS C CB  1 
ATOM 2648 S SG  . CYS B 2 28  ? 174.537 152.746 158.024 1.00 95.72  ? 34  CYS C SG  1 
ATOM 2649 N N   . ASP B 2 29  ? 177.568 151.824 161.217 1.00 98.54  ? 35  ASP C N   1 
ATOM 2650 C CA  . ASP B 2 29  ? 177.490 150.857 162.306 1.00 98.54  ? 35  ASP C CA  1 
ATOM 2651 C C   . ASP B 2 29  ? 176.410 151.231 163.317 1.00 98.54  ? 35  ASP C C   1 
ATOM 2652 O O   . ASP B 2 29  ? 175.417 150.515 163.472 1.00 98.54  ? 35  ASP C O   1 
ATOM 2653 C CB  . ASP B 2 29  ? 178.850 150.757 163.005 1.00 98.54  ? 35  ASP C CB  1 
ATOM 2654 C CG  . ASP B 2 29  ? 179.923 150.173 162.114 1.00 98.54  ? 35  ASP C CG  1 
ATOM 2655 O OD1 . ASP B 2 29  ? 179.584 149.374 161.221 1.00 98.54  ? 35  ASP C OD1 1 
ATOM 2656 O OD2 . ASP B 2 29  ? 181.107 150.510 162.312 1.00 98.54  ? 35  ASP C OD2 1 
ATOM 2657 N N   . VAL B 2 30  ? 176.585 152.357 163.990 1.00 96.74  ? 36  VAL C N   1 
ATOM 2658 C CA  . VAL B 2 30  ? 175.674 152.784 165.042 1.00 96.74  ? 36  VAL C CA  1 
ATOM 2659 C C   . VAL B 2 30  ? 174.484 153.494 164.420 1.00 96.74  ? 36  VAL C C   1 
ATOM 2660 O O   . VAL B 2 30  ? 174.624 154.252 163.452 1.00 96.74  ? 36  VAL C O   1 
ATOM 2661 C CB  . VAL B 2 30  ? 176.408 153.690 166.046 1.00 96.74  ? 36  VAL C CB  1 
ATOM 2662 C CG1 . VAL B 2 30  ? 175.457 154.192 167.113 1.00 96.74  ? 36  VAL C CG1 1 
ATOM 2663 C CG2 . VAL B 2 30  ? 177.567 152.948 166.673 1.00 96.74  ? 36  VAL C CG2 1 
ATOM 2664 N N   . THR B 2 31  ? 173.301 153.249 164.968 1.00 104.77 ? 37  THR C N   1 
ATOM 2665 C CA  . THR B 2 31  ? 172.077 153.844 164.455 1.00 104.77 ? 37  THR C CA  1 
ATOM 2666 C C   . THR B 2 31  ? 171.374 154.573 165.586 1.00 104.77 ? 37  THR C C   1 
ATOM 2667 O O   . THR B 2 31  ? 170.952 153.944 166.561 1.00 104.77 ? 37  THR C O   1 
ATOM 2668 C CB  . THR B 2 31  ? 171.169 152.776 163.858 1.00 104.77 ? 37  THR C CB  1 
ATOM 2669 O OG1 . THR B 2 31  ? 171.940 151.926 163.006 1.00 104.77 ? 37  THR C OG1 1 
ATOM 2670 C CG2 . THR B 2 31  ? 170.090 153.421 163.043 1.00 104.77 ? 37  THR C CG2 1 
ATOM 2671 N N   . ILE B 2 32  ? 171.213 155.886 165.439 1.00 102.80 ? 38  ILE C N   1 
ATOM 2672 C CA  . ILE B 2 32  ? 170.613 156.734 166.462 1.00 102.80 ? 38  ILE C CA  1 
ATOM 2673 C C   . ILE B 2 32  ? 169.143 156.924 166.134 1.00 102.80 ? 38  ILE C C   1 
ATOM 2674 O O   . ILE B 2 32  ? 168.799 157.389 165.039 1.00 102.80 ? 38  ILE C O   1 
ATOM 2675 C CB  . ILE B 2 32  ? 171.321 158.094 166.548 1.00 102.80 ? 38  ILE C CB  1 
ATOM 2676 C CG1 . ILE B 2 32  ? 172.834 157.915 166.605 1.00 102.80 ? 38  ILE C CG1 1 
ATOM 2677 C CG2 . ILE B 2 32  ? 170.829 158.852 167.763 1.00 102.80 ? 38  ILE C CG2 1 
ATOM 2678 C CD1 . ILE B 2 32  ? 173.302 157.254 167.855 1.00 102.80 ? 38  ILE C CD1 1 
ATOM 2679 N N   . PHE B 2 33  ? 168.278 156.586 167.085 1.00 117.27 ? 39  PHE C N   1 
ATOM 2680 C CA  . PHE B 2 33  ? 166.831 156.632 166.905 1.00 117.27 ? 39  PHE C CA  1 
ATOM 2681 C C   . PHE B 2 33  ? 166.261 157.766 167.747 1.00 117.27 ? 39  PHE C C   1 
ATOM 2682 O O   . PHE B 2 33  ? 166.087 157.615 168.961 1.00 117.27 ? 39  PHE C O   1 
ATOM 2683 C CB  . PHE B 2 33  ? 166.205 155.300 167.305 1.00 117.27 ? 39  PHE C CB  1 
ATOM 2684 C CG  . PHE B 2 33  ? 166.135 154.306 166.191 1.00 117.27 ? 39  PHE C CG  1 
ATOM 2685 C CD1 . PHE B 2 33  ? 167.005 154.382 165.123 1.00 117.27 ? 39  PHE C CD1 1 
ATOM 2686 C CD2 . PHE B 2 33  ? 165.207 153.281 166.221 1.00 117.27 ? 39  PHE C CD2 1 
ATOM 2687 C CE1 . PHE B 2 33  ? 166.936 153.465 164.098 1.00 117.27 ? 39  PHE C CE1 1 
ATOM 2688 C CE2 . PHE B 2 33  ? 165.141 152.356 165.197 1.00 117.27 ? 39  PHE C CE2 1 
ATOM 2689 C CZ  . PHE B 2 33  ? 166.009 152.451 164.134 1.00 117.27 ? 39  PHE C CZ  1 
ATOM 2690 N N   . VAL B 2 34  ? 165.944 158.889 167.106 1.00 119.66 ? 40  VAL C N   1 
ATOM 2691 C CA  . VAL B 2 34  ? 165.304 160.014 167.780 1.00 119.66 ? 40  VAL C CA  1 
ATOM 2692 C C   . VAL B 2 34  ? 164.018 160.350 167.034 1.00 119.66 ? 40  VAL C C   1 
ATOM 2693 O O   . VAL B 2 34  ? 164.052 160.702 165.848 1.00 119.66 ? 40  VAL C O   1 
ATOM 2694 C CB  . VAL B 2 34  ? 166.229 161.243 167.886 1.00 119.66 ? 40  VAL C CB  1 
ATOM 2695 C CG1 . VAL B 2 34  ? 167.338 160.981 168.887 1.00 119.66 ? 40  VAL C CG1 1 
ATOM 2696 C CG2 . VAL B 2 34  ? 166.842 161.585 166.547 1.00 119.66 ? 40  VAL C CG2 1 
ATOM 2697 N N   . GLU B 2 35  ? 162.885 160.203 167.723 1.00 132.37 ? 41  GLU C N   1 
ATOM 2698 C CA  . GLU B 2 35  ? 161.565 160.547 167.196 1.00 132.37 ? 41  GLU C CA  1 
ATOM 2699 C C   . GLU B 2 35  ? 161.304 159.893 165.842 1.00 132.37 ? 41  GLU C C   1 
ATOM 2700 O O   . GLU B 2 35  ? 160.817 160.527 164.903 1.00 132.37 ? 41  GLU C O   1 
ATOM 2701 C CB  . GLU B 2 35  ? 161.390 162.063 167.113 1.00 132.37 ? 41  GLU C CB  1 
ATOM 2702 C CG  . GLU B 2 35  ? 161.067 162.704 168.453 1.00 132.37 ? 41  GLU C CG  1 
ATOM 2703 C CD  . GLU B 2 35  ? 159.860 162.081 169.129 1.00 132.37 ? 41  GLU C CD  1 
ATOM 2704 O OE1 . GLU B 2 35  ? 158.939 161.621 168.421 1.00 132.37 ? 41  GLU C OE1 1 
ATOM 2705 O OE2 . GLU B 2 35  ? 159.836 162.045 170.377 1.00 132.37 ? 41  GLU C OE2 1 
ATOM 2706 N N   . GLY B 2 36  ? 161.639 158.611 165.735 1.00 129.94 ? 42  GLY C N   1 
ATOM 2707 C CA  . GLY B 2 36  ? 161.409 157.882 164.504 1.00 129.94 ? 42  GLY C CA  1 
ATOM 2708 C C   . GLY B 2 36  ? 162.491 158.139 163.481 1.00 129.94 ? 42  GLY C C   1 
ATOM 2709 O O   . GLY B 2 36  ? 162.832 157.259 162.687 1.00 129.94 ? 42  GLY C O   1 
ATOM 2710 N N   . GLN B 2 37  ? 163.027 159.356 163.486 1.00 123.49 ? 43  GLN C N   1 
ATOM 2711 C CA  . GLN B 2 37  ? 164.162 159.676 162.638 1.00 123.49 ? 43  GLN C CA  1 
ATOM 2712 C C   . GLN B 2 37  ? 165.357 158.830 163.045 1.00 123.49 ? 43  GLN C C   1 
ATOM 2713 O O   . GLN B 2 37  ? 165.591 158.589 164.232 1.00 123.49 ? 43  GLN C O   1 
ATOM 2714 C CB  . GLN B 2 37  ? 164.507 161.158 162.746 1.00 123.49 ? 43  GLN C CB  1 
ATOM 2715 C CG  . GLN B 2 37  ? 165.550 161.608 161.754 1.00 123.49 ? 43  GLN C CG  1 
ATOM 2716 C CD  . GLN B 2 37  ? 166.946 161.367 162.266 1.00 123.49 ? 43  GLN C CD  1 
ATOM 2717 O OE1 . GLN B 2 37  ? 167.185 161.384 163.468 1.00 123.49 ? 43  GLN C OE1 1 
ATOM 2718 N NE2 . GLN B 2 37  ? 167.875 161.112 161.357 1.00 123.49 ? 43  GLN C NE2 1 
ATOM 2719 N N   . ARG B 2 38  ? 166.122 158.379 162.056 1.00 106.03 ? 44  ARG C N   1 
ATOM 2720 C CA  . ARG B 2 38  ? 167.249 157.493 162.310 1.00 106.03 ? 44  ARG C CA  1 
ATOM 2721 C C   . ARG B 2 38  ? 168.493 158.037 161.633 1.00 106.03 ? 44  ARG C C   1 
ATOM 2722 O O   . ARG B 2 38  ? 168.633 157.940 160.410 1.00 106.03 ? 44  ARG C O   1 
ATOM 2723 C CB  . ARG B 2 38  ? 166.956 156.071 161.824 1.00 106.03 ? 44  ARG C CB  1 
ATOM 2724 C CG  . ARG B 2 38  ? 165.813 155.958 160.829 1.00 106.03 ? 44  ARG C CG  1 
ATOM 2725 C CD  . ARG B 2 38  ? 165.920 154.673 160.021 1.00 106.03 ? 44  ARG C CD  1 
ATOM 2726 N NE  . ARG B 2 38  ? 165.506 153.502 160.785 1.00 106.03 ? 44  ARG C NE  1 
ATOM 2727 C CZ  . ARG B 2 38  ? 164.306 153.347 161.328 1.00 106.03 ? 44  ARG C CZ  1 
ATOM 2728 N N   . PHE B 2 39  ? 169.401 158.580 162.429 1.00 105.28 ? 45  PHE C N   1 
ATOM 2729 C CA  . PHE B 2 39  ? 170.739 158.850 161.939 1.00 105.28 ? 45  PHE C CA  1 
ATOM 2730 C C   . PHE B 2 39  ? 171.498 157.542 161.842 1.00 105.28 ? 45  PHE C C   1 
ATOM 2731 O O   . PHE B 2 39  ? 171.317 156.638 162.659 1.00 105.28 ? 45  PHE C O   1 
ATOM 2732 C CB  . PHE B 2 39  ? 171.501 159.802 162.858 1.00 105.28 ? 45  PHE C CB  1 
ATOM 2733 C CG  . PHE B 2 39  ? 171.125 161.235 162.698 1.00 105.28 ? 45  PHE C CG  1 
ATOM 2734 C CD1 . PHE B 2 39  ? 171.754 162.024 161.756 1.00 105.28 ? 45  PHE C CD1 1 
ATOM 2735 C CD2 . PHE B 2 39  ? 170.159 161.800 163.504 1.00 105.28 ? 45  PHE C CD2 1 
ATOM 2736 C CE1 . PHE B 2 39  ? 171.414 163.348 161.614 1.00 105.28 ? 45  PHE C CE1 1 
ATOM 2737 C CE2 . PHE B 2 39  ? 169.813 163.123 163.367 1.00 105.28 ? 45  PHE C CE2 1 
ATOM 2738 C CZ  . PHE B 2 39  ? 170.441 163.901 162.422 1.00 105.28 ? 45  PHE C CZ  1 
ATOM 2739 N N   . ARG B 2 40  ? 172.348 157.438 160.832 1.00 82.22  ? 46  ARG C N   1 
ATOM 2740 C CA  . ARG B 2 40  ? 173.245 156.304 160.697 1.00 82.22  ? 46  ARG C CA  1 
ATOM 2741 C C   . ARG B 2 40  ? 174.664 156.835 160.691 1.00 82.22  ? 46  ARG C C   1 
ATOM 2742 O O   . ARG B 2 40  ? 175.044 157.576 159.781 1.00 82.22  ? 46  ARG C O   1 
ATOM 2743 C CB  . ARG B 2 40  ? 172.954 155.518 159.421 1.00 82.22  ? 46  ARG C CB  1 
ATOM 2744 C CG  . ARG B 2 40  ? 171.493 155.505 159.018 1.00 82.22  ? 46  ARG C CG  1 
ATOM 2745 C CD  . ARG B 2 40  ? 170.727 154.426 159.756 1.00 82.22  ? 46  ARG C CD  1 
ATOM 2746 N NE  . ARG B 2 40  ? 171.057 153.091 159.271 1.00 82.22  ? 46  ARG C NE  1 
ATOM 2747 C CZ  . ARG B 2 40  ? 171.111 152.010 160.034 1.00 82.22  ? 46  ARG C CZ  1 
ATOM 2748 N N   . ALA B 2 41  ? 175.441 156.469 161.698 1.00 74.90  ? 47  ALA C N   1 
ATOM 2749 C CA  . ALA B 2 41  ? 176.809 156.929 161.782 1.00 74.90  ? 47  ALA C CA  1 
ATOM 2750 C C   . ALA B 2 41  ? 177.668 155.759 162.217 1.00 74.90  ? 47  ALA C C   1 
ATOM 2751 O O   . ALA B 2 41  ? 177.181 154.644 162.393 1.00 74.90  ? 47  ALA C O   1 
ATOM 2752 C CB  . ALA B 2 41  ? 176.930 158.117 162.730 1.00 74.90  ? 47  ALA C CB  1 
ATOM 2753 N N   . HIS B 2 42  ? 178.951 156.005 162.388 1.00 86.55  ? 48  HIS C N   1 
ATOM 2754 C CA  . HIS B 2 42  ? 179.876 154.914 162.627 1.00 86.55  ? 48  HIS C CA  1 
ATOM 2755 C C   . HIS B 2 42  ? 179.913 154.558 164.109 1.00 86.55  ? 48  HIS C C   1 
ATOM 2756 O O   . HIS B 2 42  ? 179.131 155.064 164.915 1.00 86.55  ? 48  HIS C O   1 
ATOM 2757 C CB  . HIS B 2 42  ? 181.254 155.276 162.086 1.00 86.55  ? 48  HIS C CB  1 
ATOM 2758 C CG  . HIS B 2 42  ? 181.234 155.722 160.661 1.00 86.55  ? 48  HIS C CG  1 
ATOM 2759 N ND1 . HIS B 2 42  ? 180.250 155.337 159.777 1.00 86.55  ? 48  HIS C ND1 1 
ATOM 2760 C CD2 . HIS B 2 42  ? 182.081 156.514 159.961 1.00 86.55  ? 48  HIS C CD2 1 
ATOM 2761 C CE1 . HIS B 2 42  ? 180.487 155.878 158.596 1.00 86.55  ? 48  HIS C CE1 1 
ATOM 2762 N NE2 . HIS B 2 42  ? 181.592 156.598 158.681 1.00 86.55  ? 48  HIS C NE2 1 
ATOM 2763 N N   . ARG B 2 43  ? 180.826 153.660 164.472 1.00 89.92  ? 49  ARG C N   1 
ATOM 2764 C CA  . ARG B 2 43  ? 181.039 153.251 165.853 1.00 89.92  ? 49  ARG C CA  1 
ATOM 2765 C C   . ARG B 2 43  ? 182.082 154.109 166.552 1.00 89.92  ? 49  ARG C C   1 
ATOM 2766 O O   . ARG B 2 43  ? 181.898 154.481 167.713 1.00 89.92  ? 49  ARG C O   1 
ATOM 2767 C CB  . ARG B 2 43  ? 181.470 151.781 165.904 1.00 89.92  ? 49  ARG C CB  1 
ATOM 2768 C CG  . ARG B 2 43  ? 180.498 150.856 166.612 1.00 89.92  ? 49  ARG C CG  1 
ATOM 2769 C CD  . ARG B 2 43  ? 181.213 150.016 167.659 1.00 89.92  ? 49  ARG C CD  1 
ATOM 2770 N NE  . ARG B 2 43  ? 181.222 148.598 167.330 1.00 89.92  ? 49  ARG C NE  1 
ATOM 2771 C CZ  . ARG B 2 43  ? 180.212 147.955 166.764 1.00 89.92  ? 49  ARG C CZ  1 
ATOM 2772 N N   . SER B 2 44  ? 183.184 154.421 165.871 1.00 95.54  ? 50  SER C N   1 
ATOM 2773 C CA  . SER B 2 44  ? 184.288 155.097 166.537 1.00 95.54  ? 50  SER C CA  1 
ATOM 2774 C C   . SER B 2 44  ? 184.017 156.586 166.723 1.00 95.54  ? 50  SER C C   1 
ATOM 2775 O O   . SER B 2 44  ? 184.408 157.170 167.742 1.00 95.54  ? 50  SER C O   1 
ATOM 2776 C CB  . SER B 2 44  ? 185.574 154.877 165.749 1.00 95.54  ? 50  SER C CB  1 
ATOM 2777 O OG  . SER B 2 44  ? 185.863 153.496 165.638 1.00 95.54  ? 50  SER C OG  1 
ATOM 2778 N N   . VAL B 2 45  ? 183.362 157.224 165.755 1.00 87.78  ? 51  VAL C N   1 
ATOM 2779 C CA  . VAL B 2 45  ? 183.251 158.681 165.784 1.00 87.78  ? 51  VAL C CA  1 
ATOM 2780 C C   . VAL B 2 45  ? 182.367 159.142 166.938 1.00 87.78  ? 51  VAL C C   1 
ATOM 2781 O O   . VAL B 2 45  ? 182.742 160.036 167.706 1.00 87.78  ? 51  VAL C O   1 
ATOM 2782 C CB  . VAL B 2 45  ? 182.746 159.205 164.433 1.00 87.78  ? 51  VAL C CB  1 
ATOM 2783 C CG1 . VAL B 2 45  ? 182.358 160.654 164.553 1.00 87.78  ? 51  VAL C CG1 1 
ATOM 2784 C CG2 . VAL B 2 45  ? 183.829 159.052 163.400 1.00 87.78  ? 51  VAL C CG2 1 
ATOM 2785 N N   . LEU B 2 46  ? 181.184 158.547 167.087 1.00 85.61  ? 52  LEU C N   1 
ATOM 2786 C CA  . LEU B 2 46  ? 180.339 158.922 168.215 1.00 85.61  ? 52  LEU C CA  1 
ATOM 2787 C C   . LEU B 2 46  ? 180.988 158.567 169.541 1.00 85.61  ? 52  LEU C C   1 
ATOM 2788 O O   . LEU B 2 46  ? 180.667 159.174 170.566 1.00 85.61  ? 52  LEU C O   1 
ATOM 2789 C CB  . LEU B 2 46  ? 178.963 158.277 168.102 1.00 85.61  ? 52  LEU C CB  1 
ATOM 2790 C CG  . LEU B 2 46  ? 178.011 158.975 167.140 1.00 85.61  ? 52  LEU C CG  1 
ATOM 2791 C CD1 . LEU B 2 46  ? 178.434 158.769 165.725 1.00 85.61  ? 52  LEU C CD1 1 
ATOM 2792 C CD2 . LEU B 2 46  ? 176.616 158.440 167.340 1.00 85.61  ? 52  LEU C CD2 1 
ATOM 2793 N N   . ALA B 2 47  ? 181.894 157.592 169.547 1.00 108.39 ? 53  ALA C N   1 
ATOM 2794 C CA  . ALA B 2 47  ? 182.716 157.378 170.730 1.00 108.39 ? 53  ALA C CA  1 
ATOM 2795 C C   . ALA B 2 47  ? 183.621 158.573 170.977 1.00 108.39 ? 53  ALA C C   1 
ATOM 2796 O O   . ALA B 2 47  ? 183.837 158.970 172.126 1.00 108.39 ? 53  ALA C O   1 
ATOM 2797 C CB  . ALA B 2 47  ? 183.537 156.100 170.585 1.00 108.39 ? 53  ALA C CB  1 
ATOM 2798 N N   . ALA B 2 48  ? 184.163 159.163 169.912 1.00 96.94  ? 54  ALA C N   1 
ATOM 2799 C CA  . ALA B 2 48  ? 184.983 160.354 170.094 1.00 96.94  ? 54  ALA C CA  1 
ATOM 2800 C C   . ALA B 2 48  ? 184.161 161.570 170.494 1.00 96.94  ? 54  ALA C C   1 
ATOM 2801 O O   . ALA B 2 48  ? 184.707 162.497 171.100 1.00 96.94  ? 54  ALA C O   1 
ATOM 2802 C CB  . ALA B 2 48  ? 185.754 160.681 168.817 1.00 96.94  ? 54  ALA C CB  1 
ATOM 2803 N N   . CYS B 2 49  ? 182.871 161.594 170.166 1.00 94.82  ? 55  CYS C N   1 
ATOM 2804 C CA  . CYS B 2 49  ? 182.104 162.827 170.307 1.00 94.82  ? 55  CYS C CA  1 
ATOM 2805 C C   . CYS B 2 49  ? 181.654 163.067 171.745 1.00 94.82  ? 55  CYS C C   1 
ATOM 2806 O O   . CYS B 2 49  ? 182.136 163.988 172.412 1.00 94.82  ? 55  CYS C O   1 
ATOM 2807 C CB  . CYS B 2 49  ? 180.891 162.791 169.376 1.00 94.82  ? 55  CYS C CB  1 
ATOM 2808 S SG  . CYS B 2 49  ? 179.635 164.037 169.728 1.00 94.82  ? 55  CYS C SG  1 
ATOM 2809 N N   . SER B 2 50  ? 180.748 162.234 172.246 1.00 90.83  ? 56  SER C N   1 
ATOM 2810 C CA  . SER B 2 50  ? 180.094 162.484 173.519 1.00 90.83  ? 56  SER C CA  1 
ATOM 2811 C C   . SER B 2 50  ? 180.189 161.255 174.403 1.00 90.83  ? 56  SER C C   1 
ATOM 2812 O O   . SER B 2 50  ? 179.810 160.156 173.994 1.00 90.83  ? 56  SER C O   1 
ATOM 2813 C CB  . SER B 2 50  ? 178.627 162.854 173.321 1.00 90.83  ? 56  SER C CB  1 
ATOM 2814 O OG  . SER B 2 50  ? 177.956 162.904 174.566 1.00 90.83  ? 56  SER C OG  1 
ATOM 2815 N N   . SER B 2 51  ? 180.650 161.459 175.636 1.00 85.59  ? 57  SER C N   1 
ATOM 2816 C CA  . SER B 2 51  ? 180.865 160.333 176.528 1.00 85.59  ? 57  SER C CA  1 
ATOM 2817 C C   . SER B 2 51  ? 179.579 159.575 176.805 1.00 85.59  ? 57  SER C C   1 
ATOM 2818 O O   . SER B 2 51  ? 179.637 158.382 177.122 1.00 85.59  ? 57  SER C O   1 
ATOM 2819 C CB  . SER B 2 51  ? 181.494 160.805 177.836 1.00 85.59  ? 57  SER C CB  1 
ATOM 2820 O OG  . SER B 2 51  ? 181.697 159.718 178.719 1.00 85.59  ? 57  SER C OG  1 
ATOM 2821 N N   . TYR B 2 52  ? 178.424 160.225 176.661 1.00 79.71  ? 58  TYR C N   1 
ATOM 2822 C CA  . TYR B 2 52  ? 177.173 159.519 176.890 1.00 79.71  ? 58  TYR C CA  1 
ATOM 2823 C C   . TYR B 2 52  ? 177.021 158.348 175.931 1.00 79.71  ? 58  TYR C C   1 
ATOM 2824 O O   . TYR B 2 52  ? 176.573 157.270 176.331 1.00 79.71  ? 58  TYR C O   1 
ATOM 2825 C CB  . TYR B 2 52  ? 175.984 160.460 176.748 1.00 79.71  ? 58  TYR C CB  1 
ATOM 2826 C CG  . TYR B 2 52  ? 174.679 159.718 176.598 1.00 79.71  ? 58  TYR C CG  1 
ATOM 2827 C CD1 . TYR B 2 52  ? 174.108 159.071 177.677 1.00 79.71  ? 58  TYR C CD1 1 
ATOM 2828 C CD2 . TYR B 2 52  ? 174.028 159.647 175.381 1.00 79.71  ? 58  TYR C CD2 1 
ATOM 2829 C CE1 . TYR B 2 52  ? 172.921 158.387 177.552 1.00 79.71  ? 58  TYR C CE1 1 
ATOM 2830 C CE2 . TYR B 2 52  ? 172.845 158.962 175.248 1.00 79.71  ? 58  TYR C CE2 1 
ATOM 2831 C CZ  . TYR B 2 52  ? 172.293 158.335 176.335 1.00 79.71  ? 58  TYR C CZ  1 
ATOM 2832 N N   . PHE B 2 53  ? 177.377 158.537 174.657 1.00 95.07  ? 59  PHE C N   1 
ATOM 2833 C CA  . PHE B 2 53  ? 177.225 157.460 173.682 1.00 95.07  ? 59  PHE C CA  1 
ATOM 2834 C C   . PHE B 2 53  ? 178.271 156.369 173.880 1.00 95.07  ? 59  PHE C C   1 
ATOM 2835 O O   . PHE B 2 53  ? 177.943 155.171 173.872 1.00 95.07  ? 59  PHE C O   1 
ATOM 2836 C CB  . PHE B 2 53  ? 177.292 158.033 172.269 1.00 95.07  ? 59  PHE C CB  1 
ATOM 2837 C CG  . PHE B 2 53  ? 176.056 158.781 171.875 1.00 95.07  ? 59  PHE C CG  1 
ATOM 2838 C CD1 . PHE B 2 53  ? 174.809 158.300 172.219 1.00 95.07  ? 59  PHE C CD1 1 
ATOM 2839 C CD2 . PHE B 2 53  ? 176.136 159.977 171.189 1.00 95.07  ? 59  PHE C CD2 1 
ATOM 2840 C CE1 . PHE B 2 53  ? 173.671 158.981 171.872 1.00 95.07  ? 59  PHE C CE1 1 
ATOM 2841 C CE2 . PHE B 2 53  ? 174.994 160.663 170.843 1.00 95.07  ? 59  PHE C CE2 1 
ATOM 2842 C CZ  . PHE B 2 53  ? 173.760 160.161 171.186 1.00 95.07  ? 59  PHE C CZ  1 
ATOM 2843 N N   . HIS B 2 54  ? 179.532 156.763 174.079 1.00 140.46 ? 60  HIS C N   1 
ATOM 2844 C CA  . HIS B 2 54  ? 180.578 155.774 174.297 1.00 140.46 ? 60  HIS C CA  1 
ATOM 2845 C C   . HIS B 2 54  ? 180.326 154.983 175.571 1.00 140.46 ? 60  HIS C C   1 
ATOM 2846 O O   . HIS B 2 54  ? 180.908 153.911 175.763 1.00 140.46 ? 60  HIS C O   1 
ATOM 2847 C CB  . HIS B 2 54  ? 181.949 156.443 174.338 1.00 140.46 ? 60  HIS C CB  1 
ATOM 2848 C CG  . HIS B 2 54  ? 183.051 155.522 174.746 1.00 140.46 ? 60  HIS C CG  1 
ATOM 2849 N ND1 . HIS B 2 54  ? 183.746 154.753 173.840 1.00 140.46 ? 60  HIS C ND1 1 
ATOM 2850 C CD2 . HIS B 2 54  ? 183.570 155.233 175.960 1.00 140.46 ? 60  HIS C CD2 1 
ATOM 2851 C CE1 . HIS B 2 54  ? 184.648 154.030 174.479 1.00 140.46 ? 60  HIS C CE1 1 
ATOM 2852 N NE2 . HIS B 2 54  ? 184.562 154.303 175.767 1.00 140.46 ? 60  HIS C NE2 1 
ATOM 2853 N N   . SER B 2 55  ? 179.477 155.496 176.460 1.00 75.09  ? 61  SER C N   1 
ATOM 2854 C CA  . SER B 2 55  ? 179.006 154.660 177.553 1.00 75.09  ? 61  SER C CA  1 
ATOM 2855 C C   . SER B 2 55  ? 178.181 153.493 177.034 1.00 75.09  ? 61  SER C C   1 
ATOM 2856 O O   . SER B 2 55  ? 178.351 152.357 177.488 1.00 75.09  ? 61  SER C O   1 
ATOM 2857 C CB  . SER B 2 55  ? 178.175 155.476 178.531 1.00 75.09  ? 61  SER C CB  1 
ATOM 2858 O OG  . SER B 2 55  ? 176.972 155.899 177.919 1.00 75.09  ? 61  SER C OG  1 
ATOM 2859 N N   . ARG B 2 56  ? 177.277 153.748 176.085 1.00 85.44  ? 62  ARG C N   1 
ATOM 2860 C CA  . ARG B 2 56  ? 176.326 152.721 175.672 1.00 85.44  ? 62  ARG C CA  1 
ATOM 2861 C C   . ARG B 2 56  ? 176.821 151.860 174.522 1.00 85.44  ? 62  ARG C C   1 
ATOM 2862 O O   . ARG B 2 56  ? 176.141 150.894 174.163 1.00 85.44  ? 62  ARG C O   1 
ATOM 2863 C CB  . ARG B 2 56  ? 174.990 153.354 175.283 1.00 85.44  ? 62  ARG C CB  1 
ATOM 2864 C CG  . ARG B 2 56  ? 174.850 154.794 175.714 1.00 85.44  ? 62  ARG C CG  1 
ATOM 2865 C CD  . ARG B 2 56  ? 173.565 155.040 176.482 1.00 85.44  ? 62  ARG C CD  1 
ATOM 2866 N NE  . ARG B 2 56  ? 172.407 154.408 175.865 1.00 85.44  ? 62  ARG C NE  1 
ATOM 2867 C CZ  . ARG B 2 56  ? 171.150 154.740 176.124 1.00 85.44  ? 62  ARG C CZ  1 
ATOM 2868 N N   . ILE B 2 57  ? 177.964 152.180 173.928 1.00 83.61  ? 63  ILE C N   1 
ATOM 2869 C CA  . ILE B 2 57  ? 178.497 151.351 172.847 1.00 83.61  ? 63  ILE C CA  1 
ATOM 2870 C C   . ILE B 2 57  ? 179.465 150.295 173.356 1.00 83.61  ? 63  ILE C C   1 
ATOM 2871 O O   . ILE B 2 57  ? 179.239 149.097 173.168 1.00 83.61  ? 63  ILE C O   1 
ATOM 2872 C CB  . ILE B 2 57  ? 179.161 152.235 171.778 1.00 83.61  ? 63  ILE C CB  1 
ATOM 2873 C CG1 . ILE B 2 57  ? 178.140 153.208 171.207 1.00 83.61  ? 63  ILE C CG1 1 
ATOM 2874 C CG2 . ILE B 2 57  ? 179.786 151.376 170.708 1.00 83.61  ? 63  ILE C CG2 1 
ATOM 2875 C CD1 . ILE B 2 57  ? 176.990 152.508 170.538 1.00 83.61  ? 63  ILE C CD1 1 
ATOM 2876 N N   . VAL B 2 58  ? 180.551 150.708 174.014 1.00 74.46  ? 64  VAL C N   1 
ATOM 2877 C CA  . VAL B 2 58  ? 181.691 149.819 174.223 1.00 74.46  ? 64  VAL C CA  1 
ATOM 2878 C C   . VAL B 2 58  ? 181.312 148.587 175.029 1.00 74.46  ? 64  VAL C C   1 
ATOM 2879 O O   . VAL B 2 58  ? 182.025 147.581 174.995 1.00 74.46  ? 64  VAL C O   1 
ATOM 2880 C CB  . VAL B 2 58  ? 182.847 150.587 174.895 1.00 74.46  ? 64  VAL C CB  1 
ATOM 2881 C CG1 . VAL B 2 58  ? 182.487 150.958 176.318 1.00 74.46  ? 64  VAL C CG1 1 
ATOM 2882 C CG2 . VAL B 2 58  ? 184.137 149.791 174.830 1.00 74.46  ? 64  VAL C CG2 1 
ATOM 2883 N N   . GLY B 2 59  ? 180.190 148.625 175.728 1.00 76.90  ? 65  GLY C N   1 
ATOM 2884 C CA  . GLY B 2 59  ? 179.736 147.439 176.410 1.00 76.90  ? 65  GLY C CA  1 
ATOM 2885 C C   . GLY B 2 59  ? 179.229 146.346 175.505 1.00 76.90  ? 65  GLY C C   1 
ATOM 2886 O O   . GLY B 2 59  ? 178.860 145.268 175.980 1.00 76.90  ? 65  GLY C O   1 
ATOM 2887 N N   . GLN B 2 60  ? 179.181 146.592 174.205 1.00 71.97  ? 66  GLN C N   1 
ATOM 2888 C CA  . GLN B 2 60  ? 178.715 145.606 173.248 1.00 71.97  ? 66  GLN C CA  1 
ATOM 2889 C C   . GLN B 2 60  ? 179.692 145.528 172.086 1.00 71.97  ? 66  GLN C C   1 
ATOM 2890 O O   . GLN B 2 60  ? 180.251 146.543 171.665 1.00 71.97  ? 66  GLN C O   1 
ATOM 2891 C CB  . GLN B 2 60  ? 177.313 145.958 172.742 1.00 71.97  ? 66  GLN C CB  1 
ATOM 2892 C CG  . GLN B 2 60  ? 176.196 145.452 173.630 1.00 71.97  ? 66  GLN C CG  1 
ATOM 2893 C CD  . GLN B 2 60  ? 176.097 146.216 174.935 1.00 71.97  ? 66  GLN C CD  1 
ATOM 2894 O OE1 . GLN B 2 60  ? 176.289 147.428 174.976 1.00 71.97  ? 66  GLN C OE1 1 
ATOM 2895 N NE2 . GLN B 2 60  ? 175.804 145.503 176.013 1.00 71.97  ? 66  GLN C NE2 1 
ATOM 2896 N N   . ALA B 2 61  ? 179.915 144.312 171.591 1.00 86.61  ? 67  ALA C N   1 
ATOM 2897 C CA  . ALA B 2 61  ? 180.658 144.090 170.361 1.00 86.61  ? 67  ALA C CA  1 
ATOM 2898 C C   . ALA B 2 61  ? 179.743 143.693 169.211 1.00 86.61  ? 67  ALA C C   1 
ATOM 2899 O O   . ALA B 2 61  ? 180.216 143.168 168.197 1.00 86.61  ? 67  ALA C O   1 
ATOM 2900 C CB  . ALA B 2 61  ? 181.740 143.031 170.573 1.00 86.61  ? 67  ALA C CB  1 
ATOM 2901 N N   . ASP B 2 62  ? 178.441 143.925 169.358 1.00 89.07  ? 68  ASP C N   1 
ATOM 2902 C CA  . ASP B 2 62  ? 177.485 143.549 168.329 1.00 89.07  ? 68  ASP C CA  1 
ATOM 2903 C C   . ASP B 2 62  ? 177.767 144.322 167.046 1.00 89.07  ? 68  ASP C C   1 
ATOM 2904 O O   . ASP B 2 62  ? 178.141 145.497 167.079 1.00 89.07  ? 68  ASP C O   1 
ATOM 2905 C CB  . ASP B 2 62  ? 176.061 143.833 168.814 1.00 89.07  ? 68  ASP C CB  1 
ATOM 2906 C CG  . ASP B 2 62  ? 175.746 143.158 170.138 1.00 89.07  ? 68  ASP C CG  1 
ATOM 2907 O OD1 . ASP B 2 62  ? 176.348 142.106 170.433 1.00 89.07  ? 68  ASP C OD1 1 
ATOM 2908 O OD2 . ASP B 2 62  ? 174.900 143.689 170.890 1.00 89.07  ? 68  ASP C OD2 1 
ATOM 2909 N N   . GLY B 2 63  ? 177.596 143.650 165.906 1.00 88.44  ? 69  GLY C N   1 
ATOM 2910 C CA  . GLY B 2 63  ? 177.848 144.308 164.634 1.00 88.44  ? 69  GLY C CA  1 
ATOM 2911 C C   . GLY B 2 63  ? 176.875 145.437 164.354 1.00 88.44  ? 69  GLY C C   1 
ATOM 2912 O O   . GLY B 2 63  ? 177.267 146.499 163.866 1.00 88.44  ? 69  GLY C O   1 
ATOM 2913 N N   . GLU B 2 64  ? 175.599 145.222 164.652 1.00 88.99  ? 70  GLU C N   1 
ATOM 2914 C CA  . GLU B 2 64  ? 174.570 146.242 164.516 1.00 88.99  ? 70  GLU C CA  1 
ATOM 2915 C C   . GLU B 2 64  ? 174.155 146.698 165.906 1.00 88.99  ? 70  GLU C C   1 
ATOM 2916 O O   . GLU B 2 64  ? 173.966 145.869 166.802 1.00 88.99  ? 70  GLU C O   1 
ATOM 2917 C CB  . GLU B 2 64  ? 173.356 145.710 163.754 1.00 88.99  ? 70  GLU C CB  1 
ATOM 2918 C CG  . GLU B 2 64  ? 172.469 146.797 163.174 1.00 88.99  ? 70  GLU C CG  1 
ATOM 2919 C CD  . GLU B 2 64  ? 171.463 147.325 164.177 1.00 88.99  ? 70  GLU C CD  1 
ATOM 2920 O OE1 . GLU B 2 64  ? 171.240 146.658 165.207 1.00 88.99  ? 70  GLU C OE1 1 
ATOM 2921 O OE2 . GLU B 2 64  ? 170.891 148.407 163.935 1.00 88.99  ? 70  GLU C OE2 1 
ATOM 2922 N N   . LEU B 2 65  ? 174.015 148.009 166.083 1.00 79.12  ? 71  LEU C N   1 
ATOM 2923 C CA  . LEU B 2 65  ? 173.679 148.598 167.369 1.00 79.12  ? 71  LEU C CA  1 
ATOM 2924 C C   . LEU B 2 65  ? 172.449 149.482 167.225 1.00 79.12  ? 71  LEU C C   1 
ATOM 2925 O O   . LEU B 2 65  ? 172.072 149.883 166.122 1.00 79.12  ? 71  LEU C O   1 
ATOM 2926 C CB  . LEU B 2 65  ? 174.856 149.407 167.925 1.00 79.12  ? 71  LEU C CB  1 
ATOM 2927 C CG  . LEU B 2 65  ? 176.142 148.605 168.089 1.00 79.12  ? 71  LEU C CG  1 
ATOM 2928 C CD1 . LEU B 2 65  ? 177.349 149.472 167.856 1.00 79.12  ? 71  LEU C CD1 1 
ATOM 2929 C CD2 . LEU B 2 65  ? 176.182 148.023 169.475 1.00 79.12  ? 71  LEU C CD2 1 
ATOM 2930 N N   . ASN B 2 66  ? 171.808 149.767 168.354 1.00 86.30  ? 72  ASN C N   1 
ATOM 2931 C CA  . ASN B 2 66  ? 170.657 150.657 168.384 1.00 86.30  ? 72  ASN C CA  1 
ATOM 2932 C C   . ASN B 2 66  ? 170.753 151.516 169.632 1.00 86.30  ? 72  ASN C C   1 
ATOM 2933 O O   . ASN B 2 66  ? 171.162 151.025 170.686 1.00 86.30  ? 72  ASN C O   1 
ATOM 2934 C CB  . ASN B 2 66  ? 169.345 149.874 168.389 1.00 86.30  ? 72  ASN C CB  1 
ATOM 2935 C CG  . ASN B 2 66  ? 169.165 149.050 167.146 1.00 86.30  ? 72  ASN C CG  1 
ATOM 2936 O OD1 . ASN B 2 66  ? 169.313 149.545 166.034 1.00 86.30  ? 72  ASN C OD1 1 
ATOM 2937 N ND2 . ASN B 2 66  ? 168.836 147.779 167.325 1.00 86.30  ? 72  ASN C ND2 1 
ATOM 2938 N N   . ILE B 2 67  ? 170.412 152.796 169.511 1.00 94.23  ? 73  ILE C N   1 
ATOM 2939 C CA  . ILE B 2 67  ? 170.388 153.711 170.645 1.00 94.23  ? 73  ILE C CA  1 
ATOM 2940 C C   . ILE B 2 67  ? 169.168 154.610 170.526 1.00 94.23  ? 73  ILE C C   1 
ATOM 2941 O O   . ILE B 2 67  ? 168.835 155.076 169.432 1.00 94.23  ? 73  ILE C O   1 
ATOM 2942 C CB  . ILE B 2 67  ? 171.662 154.575 170.733 1.00 94.23  ? 73  ILE C CB  1 
ATOM 2943 C CG1 . ILE B 2 67  ? 172.925 153.719 170.716 1.00 94.23  ? 73  ILE C CG1 1 
ATOM 2944 C CG2 . ILE B 2 67  ? 171.631 155.416 171.991 1.00 94.23  ? 73  ILE C CG2 1 
ATOM 2945 C CD1 . ILE B 2 67  ? 174.193 154.530 170.701 1.00 94.23  ? 73  ILE C CD1 1 
ATOM 2946 N N   . THR B 2 68  ? 168.512 154.866 171.654 1.00 136.31 ? 74  THR C N   1 
ATOM 2947 C CA  . THR B 2 68  ? 167.502 155.907 171.752 1.00 136.31 ? 74  THR C CA  1 
ATOM 2948 C C   . THR B 2 68  ? 168.001 156.998 172.690 1.00 136.31 ? 74  THR C C   1 
ATOM 2949 O O   . THR B 2 68  ? 168.932 156.792 173.472 1.00 136.31 ? 74  THR C O   1 
ATOM 2950 C CB  . THR B 2 68  ? 166.156 155.354 172.246 1.00 136.31 ? 74  THR C CB  1 
ATOM 2951 O OG1 . THR B 2 68  ? 165.157 156.379 172.162 1.00 136.31 ? 74  THR C OG1 1 
ATOM 2952 C CG2 . THR B 2 68  ? 166.266 154.869 173.683 1.00 136.31 ? 74  THR C CG2 1 
ATOM 2953 N N   . LEU B 2 69  ? 167.385 158.168 172.595 1.00 159.58 ? 75  LEU C N   1 
ATOM 2954 C CA  . LEU B 2 69  ? 167.766 159.341 173.363 1.00 159.58 ? 75  LEU C CA  1 
ATOM 2955 C C   . LEU B 2 69  ? 166.564 159.864 174.138 1.00 159.58 ? 75  LEU C C   1 
ATOM 2956 O O   . LEU B 2 69  ? 165.415 159.626 173.747 1.00 159.58 ? 75  LEU C O   1 
ATOM 2957 C CB  . LEU B 2 69  ? 168.313 160.443 172.443 1.00 159.58 ? 75  LEU C CB  1 
ATOM 2958 C CG  . LEU B 2 69  ? 169.817 160.460 172.162 1.00 159.58 ? 75  LEU C CG  1 
ATOM 2959 C CD1 . LEU B 2 69  ? 170.592 160.691 173.437 1.00 159.58 ? 75  LEU C CD1 1 
ATOM 2960 C CD2 . LEU B 2 69  ? 170.269 159.178 171.489 1.00 159.58 ? 75  LEU C CD2 1 
ATOM 2961 N N   . PRO B 2 70  ? 166.787 160.572 175.246 1.00 200.70 ? 76  PRO C N   1 
ATOM 2962 C CA  . PRO B 2 70  ? 165.656 161.061 176.041 1.00 200.70 ? 76  PRO C CA  1 
ATOM 2963 C C   . PRO B 2 70  ? 164.774 162.015 175.250 1.00 200.70 ? 76  PRO C C   1 
ATOM 2964 O O   . PRO B 2 70  ? 165.220 162.718 174.341 1.00 200.70 ? 76  PRO C O   1 
ATOM 2965 C CB  . PRO B 2 70  ? 166.328 161.775 177.220 1.00 200.70 ? 76  PRO C CB  1 
ATOM 2966 C CG  . PRO B 2 70  ? 167.682 161.178 177.302 1.00 200.70 ? 76  PRO C CG  1 
ATOM 2967 C CD  . PRO B 2 70  ? 168.076 160.868 175.894 1.00 200.70 ? 76  PRO C CD  1 
ATOM 2968 N N   . GLU B 2 71  ? 163.490 162.026 175.620 1.00 234.33 ? 77  GLU C N   1 
ATOM 2969 C CA  . GLU B 2 71  ? 162.517 162.915 174.995 1.00 234.33 ? 77  GLU C CA  1 
ATOM 2970 C C   . GLU B 2 71  ? 162.905 164.380 175.151 1.00 234.33 ? 77  GLU C C   1 
ATOM 2971 O O   . GLU B 2 71  ? 162.451 165.222 174.368 1.00 234.33 ? 77  GLU C O   1 
ATOM 2972 C CB  . GLU B 2 71  ? 161.132 162.663 175.606 1.00 234.33 ? 77  GLU C CB  1 
ATOM 2973 C CG  . GLU B 2 71  ? 159.970 163.427 174.977 1.00 234.33 ? 77  GLU C CG  1 
ATOM 2974 C CD  . GLU B 2 71  ? 159.704 163.022 173.544 1.00 234.33 ? 77  GLU C CD  1 
ATOM 2975 O OE1 . GLU B 2 71  ? 159.773 161.811 173.250 1.00 234.33 ? 77  GLU C OE1 1 
ATOM 2976 O OE2 . GLU B 2 71  ? 159.416 163.911 172.715 1.00 234.33 ? 77  GLU C OE2 1 
ATOM 2977 N N   . GLU B 2 72  ? 163.740 164.698 176.140 1.00 236.88 ? 78  GLU C N   1 
ATOM 2978 C CA  . GLU B 2 72  ? 164.151 166.077 176.358 1.00 236.88 ? 78  GLU C CA  1 
ATOM 2979 C C   . GLU B 2 72  ? 164.996 166.624 175.215 1.00 236.88 ? 78  GLU C C   1 
ATOM 2980 O O   . GLU B 2 72  ? 164.878 167.811 174.892 1.00 236.88 ? 78  GLU C O   1 
ATOM 2981 C CB  . GLU B 2 72  ? 164.933 166.186 177.666 1.00 236.88 ? 78  GLU C CB  1 
ATOM 2982 C CG  . GLU B 2 72  ? 164.108 166.010 178.927 1.00 236.88 ? 78  GLU C CG  1 
ATOM 2983 C CD  . GLU B 2 72  ? 164.928 166.243 180.182 1.00 236.88 ? 78  GLU C CD  1 
ATOM 2984 O OE1 . GLU B 2 72  ? 166.172 166.242 180.084 1.00 236.88 ? 78  GLU C OE1 1 
ATOM 2985 O OE2 . GLU B 2 72  ? 164.331 166.426 181.263 1.00 236.88 ? 78  GLU C OE2 1 
ATOM 2986 N N   . VAL B 2 73  ? 165.840 165.802 174.598 1.00 203.06 ? 79  VAL C N   1 
ATOM 2987 C CA  . VAL B 2 73  ? 166.740 166.289 173.557 1.00 203.06 ? 79  VAL C CA  1 
ATOM 2988 C C   . VAL B 2 73  ? 165.944 166.510 172.280 1.00 203.06 ? 79  VAL C C   1 
ATOM 2989 O O   . VAL B 2 73  ? 165.281 165.594 171.780 1.00 203.06 ? 79  VAL C O   1 
ATOM 2990 C CB  . VAL B 2 73  ? 167.896 165.306 173.326 1.00 203.06 ? 79  VAL C CB  1 
ATOM 2991 C CG1 . VAL B 2 73  ? 168.757 165.774 172.165 1.00 203.06 ? 79  VAL C CG1 1 
ATOM 2992 C CG2 . VAL B 2 73  ? 168.724 165.160 174.585 1.00 203.06 ? 79  VAL C CG2 1 
ATOM 2993 N N   . THR B 2 74  ? 166.021 167.722 171.741 1.00 168.33 ? 80  THR C N   1 
ATOM 2994 C CA  . THR B 2 74  ? 165.181 168.117 170.621 1.00 168.33 ? 80  THR C CA  1 
ATOM 2995 C C   . THR B 2 74  ? 165.827 167.734 169.298 1.00 168.33 ? 80  THR C C   1 
ATOM 2996 O O   . THR B 2 74  ? 167.052 167.763 169.155 1.00 168.33 ? 80  THR C O   1 
ATOM 2997 C CB  . THR B 2 74  ? 164.901 169.622 170.654 1.00 168.33 ? 80  THR C CB  1 
ATOM 2998 O OG1 . THR B 2 74  ? 163.963 169.957 169.625 1.00 168.33 ? 80  THR C OG1 1 
ATOM 2999 C CG2 . THR B 2 74  ? 166.181 170.423 170.461 1.00 168.33 ? 80  THR C CG2 1 
ATOM 3000 N N   . VAL B 2 75  ? 164.985 167.358 168.336 1.00 147.24 ? 81  VAL C N   1 
ATOM 3001 C CA  . VAL B 2 75  ? 165.478 166.957 167.024 1.00 147.24 ? 81  VAL C CA  1 
ATOM 3002 C C   . VAL B 2 75  ? 166.078 168.150 166.291 1.00 147.24 ? 81  VAL C C   1 
ATOM 3003 O O   . VAL B 2 75  ? 167.090 168.020 165.590 1.00 147.24 ? 81  VAL C O   1 
ATOM 3004 C CB  . VAL B 2 75  ? 164.346 166.290 166.221 1.00 147.24 ? 81  VAL C CB  1 
ATOM 3005 C CG1 . VAL B 2 75  ? 163.152 167.222 166.095 1.00 147.24 ? 81  VAL C CG1 1 
ATOM 3006 C CG2 . VAL B 2 75  ? 164.841 165.855 164.851 1.00 147.24 ? 81  VAL C CG2 1 
ATOM 3007 N N   . LYS B 2 76  ? 165.477 169.332 166.453 1.00 144.15 ? 82  LYS C N   1 
ATOM 3008 C CA  . LYS B 2 76  ? 165.969 170.513 165.750 1.00 144.15 ? 82  LYS C CA  1 
ATOM 3009 C C   . LYS B 2 76  ? 167.394 170.847 166.167 1.00 144.15 ? 82  LYS C C   1 
ATOM 3010 O O   . LYS B 2 76  ? 168.242 171.147 165.320 1.00 144.15 ? 82  LYS C O   1 
ATOM 3011 C CB  . LYS B 2 76  ? 165.031 171.700 165.992 1.00 144.15 ? 82  LYS C CB  1 
ATOM 3012 C CG  . LYS B 2 76  ? 164.869 172.133 167.448 1.00 144.15 ? 82  LYS C CG  1 
ATOM 3013 C CD  . LYS B 2 76  ? 165.742 173.342 167.769 1.00 144.15 ? 82  LYS C CD  1 
ATOM 3014 C CE  . LYS B 2 76  ? 165.512 173.847 169.184 1.00 144.15 ? 82  LYS C CE  1 
ATOM 3015 N NZ  . LYS B 2 76  ? 166.374 175.022 169.498 1.00 144.15 ? 82  LYS C NZ  1 
ATOM 3016 N N   . GLY B 2 77  ? 167.682 170.787 167.469 1.00 140.44 ? 83  GLY C N   1 
ATOM 3017 C CA  . GLY B 2 77  ? 169.045 170.984 167.918 1.00 140.44 ? 83  GLY C CA  1 
ATOM 3018 C C   . GLY B 2 77  ? 169.902 169.761 167.703 1.00 140.44 ? 83  GLY C C   1 
ATOM 3019 O O   . GLY B 2 77  ? 171.128 169.869 167.621 1.00 140.44 ? 83  GLY C O   1 
ATOM 3020 N N   . PHE B 2 78  ? 169.276 168.593 167.591 1.00 129.25 ? 84  PHE C N   1 
ATOM 3021 C CA  . PHE B 2 78  ? 170.032 167.371 167.374 1.00 129.25 ? 84  PHE C CA  1 
ATOM 3022 C C   . PHE B 2 78  ? 170.635 167.298 165.980 1.00 129.25 ? 84  PHE C C   1 
ATOM 3023 O O   . PHE B 2 78  ? 171.747 166.784 165.823 1.00 129.25 ? 84  PHE C O   1 
ATOM 3024 C CB  . PHE B 2 78  ? 169.147 166.154 167.635 1.00 129.25 ? 84  PHE C CB  1 
ATOM 3025 C CG  . PHE B 2 78  ? 169.894 164.863 167.635 1.00 129.25 ? 84  PHE C CG  1 
ATOM 3026 C CD1 . PHE B 2 78  ? 170.886 164.620 168.565 1.00 129.25 ? 84  PHE C CD1 1 
ATOM 3027 C CD2 . PHE B 2 78  ? 169.588 163.883 166.717 1.00 129.25 ? 84  PHE C CD2 1 
ATOM 3028 C CE1 . PHE B 2 78  ? 171.572 163.436 168.560 1.00 129.25 ? 84  PHE C CE1 1 
ATOM 3029 C CE2 . PHE B 2 78  ? 170.266 162.694 166.717 1.00 129.25 ? 84  PHE C CE2 1 
ATOM 3030 C CZ  . PHE B 2 78  ? 171.259 162.470 167.636 1.00 129.25 ? 84  PHE C CZ  1 
ATOM 3031 N N   . GLU B 2 79  ? 169.934 167.814 164.976 1.00 101.64 ? 85  GLU C N   1 
ATOM 3032 C CA  . GLU B 2 79  ? 170.393 167.667 163.597 1.00 101.64 ? 85  GLU C CA  1 
ATOM 3033 C C   . GLU B 2 79  ? 171.789 168.245 163.378 1.00 101.64 ? 85  GLU C C   1 
ATOM 3034 O O   . GLU B 2 79  ? 172.642 167.539 162.814 1.00 101.64 ? 85  GLU C O   1 
ATOM 3035 C CB  . GLU B 2 79  ? 169.357 168.303 162.664 1.00 101.64 ? 85  GLU C CB  1 
ATOM 3036 C CG  . GLU B 2 79  ? 169.809 168.642 161.247 1.00 101.64 ? 85  GLU C CG  1 
ATOM 3037 C CD  . GLU B 2 79  ? 170.589 167.524 160.575 1.00 101.64 ? 85  GLU C CD  1 
ATOM 3038 O OE1 . GLU B 2 79  ? 171.809 167.679 160.362 1.00 101.64 ? 85  GLU C OE1 1 
ATOM 3039 O OE2 . GLU B 2 79  ? 169.968 166.487 160.260 1.00 101.64 ? 85  GLU C OE2 1 
ATOM 3040 N N   . PRO B 2 80  ? 172.104 169.478 163.794 1.00 98.51  ? 86  PRO C N   1 
ATOM 3041 C CA  . PRO B 2 80  ? 173.445 170.015 163.507 1.00 98.51  ? 86  PRO C CA  1 
ATOM 3042 C C   . PRO B 2 80  ? 174.560 169.304 164.246 1.00 98.51  ? 86  PRO C C   1 
ATOM 3043 O O   . PRO B 2 80  ? 175.719 169.399 163.825 1.00 98.51  ? 86  PRO C O   1 
ATOM 3044 C CB  . PRO B 2 80  ? 173.344 171.481 163.956 1.00 98.51  ? 86  PRO C CB  1 
ATOM 3045 C CG  . PRO B 2 80  ? 171.875 171.768 164.035 1.00 98.51  ? 86  PRO C CG  1 
ATOM 3046 C CD  . PRO B 2 80  ? 171.259 170.483 164.462 1.00 98.51  ? 86  PRO C CD  1 
ATOM 3047 N N   . LEU B 2 81  ? 174.246 168.603 165.337 1.00 104.44 ? 87  LEU C N   1 
ATOM 3048 C CA  . LEU B 2 81  ? 175.291 168.007 166.159 1.00 104.44 ? 87  LEU C CA  1 
ATOM 3049 C C   . LEU B 2 81  ? 176.047 166.929 165.414 1.00 104.44 ? 87  LEU C C   1 
ATOM 3050 O O   . LEU B 2 81  ? 177.247 166.751 165.636 1.00 104.44 ? 87  LEU C O   1 
ATOM 3051 C CB  . LEU B 2 81  ? 174.696 167.389 167.410 1.00 104.44 ? 87  LEU C CB  1 
ATOM 3052 C CG  . LEU B 2 81  ? 173.744 168.237 168.218 1.00 104.44 ? 87  LEU C CG  1 
ATOM 3053 C CD1 . LEU B 2 81  ? 172.983 167.308 169.115 1.00 104.44 ? 87  LEU C CD1 1 
ATOM 3054 C CD2 . LEU B 2 81  ? 174.520 169.253 169.008 1.00 104.44 ? 87  LEU C CD2 1 
ATOM 3055 N N   . ILE B 2 82  ? 175.355 166.163 164.578 1.00 94.45  ? 88  ILE C N   1 
ATOM 3056 C CA  . ILE B 2 82  ? 176.021 165.094 163.849 1.00 94.45  ? 88  ILE C CA  1 
ATOM 3057 C C   . ILE B 2 82  ? 177.056 165.672 162.895 1.00 94.45  ? 88  ILE C C   1 
ATOM 3058 O O   . ILE B 2 82  ? 178.192 165.190 162.825 1.00 94.45  ? 88  ILE C O   1 
ATOM 3059 C CB  . ILE B 2 82  ? 174.979 164.228 163.123 1.00 94.45  ? 88  ILE C CB  1 
ATOM 3060 C CG1 . ILE B 2 82  ? 173.958 163.674 164.121 1.00 94.45  ? 88  ILE C CG1 1 
ATOM 3061 C CG2 . ILE B 2 82  ? 175.646 163.109 162.383 1.00 94.45  ? 88  ILE C CG2 1 
ATOM 3062 C CD1 . ILE B 2 82  ? 174.579 163.032 165.338 1.00 94.45  ? 88  ILE C CD1 1 
ATOM 3063 N N   . GLN B 2 83  ? 176.687 166.721 162.158 1.00 97.68  ? 89  GLN C N   1 
ATOM 3064 C CA  . GLN B 2 83  ? 177.655 167.400 161.303 1.00 97.68  ? 89  GLN C CA  1 
ATOM 3065 C C   . GLN B 2 83  ? 178.778 168.017 162.123 1.00 97.68  ? 89  GLN C C   1 
ATOM 3066 O O   . GLN B 2 83  ? 179.934 168.033 161.685 1.00 97.68  ? 89  GLN C O   1 
ATOM 3067 C CB  . GLN B 2 83  ? 176.958 168.451 160.442 1.00 97.68  ? 89  GLN C CB  1 
ATOM 3068 C CG  . GLN B 2 83  ? 176.476 167.919 159.098 1.00 97.68  ? 89  GLN C CG  1 
ATOM 3069 C CD  . GLN B 2 83  ? 175.197 167.117 159.191 1.00 97.68  ? 89  GLN C CD  1 
ATOM 3070 O OE1 . GLN B 2 83  ? 174.480 167.183 160.188 1.00 97.68  ? 89  GLN C OE1 1 
ATOM 3071 N NE2 . GLN B 2 83  ? 174.909 166.342 158.151 1.00 97.68  ? 89  GLN C NE2 1 
ATOM 3072 N N   . PHE B 2 84  ? 178.460 168.537 163.308 1.00 94.69  ? 90  PHE C N   1 
ATOM 3073 C CA  . PHE B 2 84  ? 179.511 168.950 164.233 1.00 94.69  ? 90  PHE C CA  1 
ATOM 3074 C C   . PHE B 2 84  ? 180.503 167.830 164.498 1.00 94.69  ? 90  PHE C C   1 
ATOM 3075 O O   . PHE B 2 84  ? 181.718 168.011 164.361 1.00 94.69  ? 90  PHE C O   1 
ATOM 3076 C CB  . PHE B 2 84  ? 178.901 169.415 165.550 1.00 94.69  ? 90  PHE C CB  1 
ATOM 3077 C CG  . PHE B 2 84  ? 179.918 169.863 166.541 1.00 94.69  ? 90  PHE C CG  1 
ATOM 3078 C CD1 . PHE B 2 84  ? 180.551 171.081 166.418 1.00 94.69  ? 90  PHE C CD1 1 
ATOM 3079 C CD2 . PHE B 2 84  ? 180.250 169.042 167.603 1.00 94.69  ? 90  PHE C CD2 1 
ATOM 3080 C CE1 . PHE B 2 84  ? 181.499 171.468 167.334 1.00 94.69  ? 90  PHE C CE1 1 
ATOM 3081 C CE2 . PHE B 2 84  ? 181.191 169.428 168.526 1.00 94.69  ? 90  PHE C CE2 1 
ATOM 3082 C CZ  . PHE B 2 84  ? 181.816 170.644 168.393 1.00 94.69  ? 90  PHE C CZ  1 
ATOM 3083 N N   . ALA B 2 85  ? 179.997 166.667 164.885 1.00 95.10  ? 91  ALA C N   1 
ATOM 3084 C CA  . ALA B 2 85  ? 180.875 165.560 165.226 1.00 95.10  ? 91  ALA C CA  1 
ATOM 3085 C C   . ALA B 2 85  ? 181.705 165.147 164.025 1.00 95.10  ? 91  ALA C C   1 
ATOM 3086 O O   . ALA B 2 85  ? 182.908 164.891 164.149 1.00 95.10  ? 91  ALA C O   1 
ATOM 3087 C CB  . ALA B 2 85  ? 180.056 164.383 165.749 1.00 95.10  ? 91  ALA C CB  1 
ATOM 3088 N N   . TYR B 2 86  ? 181.086 165.106 162.852 1.00 97.06  ? 92  TYR C N   1 
ATOM 3089 C CA  . TYR B 2 86  ? 181.769 164.583 161.680 1.00 97.06  ? 92  TYR C CA  1 
ATOM 3090 C C   . TYR B 2 86  ? 182.783 165.560 161.102 1.00 97.06  ? 92  TYR C C   1 
ATOM 3091 O O   . TYR B 2 86  ? 183.840 165.132 160.630 1.00 97.06  ? 92  TYR C O   1 
ATOM 3092 C CB  . TYR B 2 86  ? 180.748 164.191 160.619 1.00 97.06  ? 92  TYR C CB  1 
ATOM 3093 C CG  . TYR B 2 86  ? 180.170 162.817 160.826 1.00 97.06  ? 92  TYR C CG  1 
ATOM 3094 C CD1 . TYR B 2 86  ? 180.793 161.707 160.292 1.00 97.06  ? 92  TYR C CD1 1 
ATOM 3095 C CD2 . TYR B 2 86  ? 179.002 162.631 161.540 1.00 97.06  ? 92  TYR C CD2 1 
ATOM 3096 C CE1 . TYR B 2 86  ? 180.278 160.454 160.474 1.00 97.06  ? 92  TYR C CE1 1 
ATOM 3097 C CE2 . TYR B 2 86  ? 178.478 161.378 161.723 1.00 97.06  ? 92  TYR C CE2 1 
ATOM 3098 C CZ  . TYR B 2 86  ? 179.117 160.293 161.186 1.00 97.06  ? 92  TYR C CZ  1 
ATOM 3099 N N   . THR B 2 87  ? 182.499 166.861 161.136 1.00 99.12  ? 93  THR C N   1 
ATOM 3100 C CA  . THR B 2 87  ? 183.376 167.844 160.514 1.00 99.12  ? 93  THR C CA  1 
ATOM 3101 C C   . THR B 2 87  ? 184.258 168.583 161.508 1.00 99.12  ? 93  THR C C   1 
ATOM 3102 O O   . THR B 2 87  ? 185.199 169.263 161.082 1.00 99.12  ? 93  THR C O   1 
ATOM 3103 C CB  . THR B 2 87  ? 182.555 168.878 159.731 1.00 99.12  ? 93  THR C CB  1 
ATOM 3104 O OG1 . THR B 2 87  ? 181.710 169.601 160.633 1.00 99.12  ? 93  THR C OG1 1 
ATOM 3105 C CG2 . THR B 2 87  ? 181.692 168.197 158.689 1.00 99.12  ? 93  THR C CG2 1 
ATOM 3106 N N   . ALA B 2 88  ? 183.983 168.462 162.806 1.00 109.57 ? 94  ALA C N   1 
ATOM 3107 C CA  . ALA B 2 88  ? 184.648 169.261 163.832 1.00 109.57 ? 94  ALA C CA  1 
ATOM 3108 C C   . ALA B 2 88  ? 184.530 170.745 163.500 1.00 109.57 ? 94  ALA C C   1 
ATOM 3109 O O   . ALA B 2 88  ? 185.490 171.511 163.597 1.00 109.57 ? 94  ALA C O   1 
ATOM 3110 C CB  . ALA B 2 88  ? 186.110 168.846 164.002 1.00 109.57 ? 94  ALA C CB  1 
ATOM 3111 N N   . LYS B 2 89  ? 183.330 171.147 163.087 1.00 129.69 ? 95  LYS C N   1 
ATOM 3112 C CA  . LYS B 2 89  ? 183.087 172.498 162.611 1.00 129.69 ? 95  LYS C CA  1 
ATOM 3113 C C   . LYS B 2 89  ? 181.916 173.100 163.375 1.00 129.69 ? 95  LYS C C   1 
ATOM 3114 O O   . LYS B 2 89  ? 180.997 172.389 163.789 1.00 129.69 ? 95  LYS C O   1 
ATOM 3115 C CB  . LYS B 2 89  ? 182.786 172.507 161.110 1.00 129.69 ? 95  LYS C CB  1 
ATOM 3116 C CG  . LYS B 2 89  ? 183.990 172.780 160.227 1.00 129.69 ? 95  LYS C CG  1 
ATOM 3117 C CD  . LYS B 2 89  ? 184.676 174.093 160.537 1.00 129.69 ? 95  LYS C CD  1 
ATOM 3118 C CE  . LYS B 2 89  ? 183.709 175.246 160.620 1.00 129.69 ? 95  LYS C CE  1 
ATOM 3119 N NZ  . LYS B 2 89  ? 184.430 176.446 161.091 1.00 129.69 ? 95  LYS C NZ  1 
ATOM 3120 N N   . LEU B 2 90  ? 181.950 174.416 163.557 1.00 144.98 ? 96  LEU C N   1 
ATOM 3121 C CA  . LEU B 2 90  ? 180.911 175.134 164.287 1.00 144.98 ? 96  LEU C CA  1 
ATOM 3122 C C   . LEU B 2 90  ? 180.043 175.935 163.327 1.00 144.98 ? 96  LEU C C   1 
ATOM 3123 O O   . LEU B 2 90  ? 180.539 176.822 162.626 1.00 144.98 ? 96  LEU C O   1 
ATOM 3124 C CB  . LEU B 2 90  ? 181.520 176.056 165.339 1.00 144.98 ? 96  LEU C CB  1 
ATOM 3125 C CG  . LEU B 2 90  ? 182.020 175.348 166.590 1.00 144.98 ? 96  LEU C CG  1 
ATOM 3126 C CD1 . LEU B 2 90  ? 182.714 176.325 167.513 1.00 144.98 ? 96  LEU C CD1 1 
ATOM 3127 C CD2 . LEU B 2 90  ? 180.830 174.729 167.283 1.00 144.98 ? 96  LEU C CD2 1 
ATOM 3128 N N   . ILE B 2 91  ? 178.749 175.623 163.304 1.00 138.05 ? 97  ILE C N   1 
ATOM 3129 C CA  . ILE B 2 91  ? 177.752 176.383 162.559 1.00 138.05 ? 97  ILE C CA  1 
ATOM 3130 C C   . ILE B 2 91  ? 176.575 176.636 163.491 1.00 138.05 ? 97  ILE C C   1 
ATOM 3131 O O   . ILE B 2 91  ? 176.097 175.712 164.160 1.00 138.05 ? 97  ILE C O   1 
ATOM 3132 C CB  . ILE B 2 91  ? 177.301 175.657 161.280 1.00 138.05 ? 97  ILE C CB  1 
ATOM 3133 C CG1 . ILE B 2 91  ? 176.630 174.323 161.609 1.00 138.05 ? 97  ILE C CG1 1 
ATOM 3134 C CG2 . ILE B 2 91  ? 178.489 175.410 160.370 1.00 138.05 ? 97  ILE C CG2 1 
ATOM 3135 C CD1 . ILE B 2 91  ? 175.964 173.676 160.424 1.00 138.05 ? 97  ILE C CD1 1 
ATOM 3136 N N   . LEU B 2 92  ? 176.134 177.887 163.571 1.00 145.97 ? 98  LEU C N   1 
ATOM 3137 C CA  . LEU B 2 92  ? 175.084 178.247 164.511 1.00 145.97 ? 98  LEU C CA  1 
ATOM 3138 C C   . LEU B 2 92  ? 174.197 179.340 163.934 1.00 145.97 ? 98  LEU C C   1 
ATOM 3139 O O   . LEU B 2 92  ? 174.608 180.102 163.057 1.00 145.97 ? 98  LEU C O   1 
ATOM 3140 C CB  . LEU B 2 92  ? 175.679 178.701 165.847 1.00 145.97 ? 98  LEU C CB  1 
ATOM 3141 C CG  . LEU B 2 92  ? 174.750 178.809 167.052 1.00 145.97 ? 98  LEU C CG  1 
ATOM 3142 C CD1 . LEU B 2 92  ? 173.908 177.563 167.160 1.00 145.97 ? 98  LEU C CD1 1 
ATOM 3143 C CD2 . LEU B 2 92  ? 175.576 179.007 168.305 1.00 145.97 ? 98  LEU C CD2 1 
ATOM 3144 N N   . SER B 2 93  ? 172.967 179.398 164.436 1.00 157.87 ? 99  SER C N   1 
ATOM 3145 C CA  . SER B 2 93  ? 172.013 180.435 164.084 1.00 157.87 ? 99  SER C CA  1 
ATOM 3146 C C   . SER B 2 93  ? 171.420 181.013 165.360 1.00 157.87 ? 99  SER C C   1 
ATOM 3147 O O   . SER B 2 93  ? 171.364 180.345 166.395 1.00 157.87 ? 99  SER C O   1 
ATOM 3148 C CB  . SER B 2 93  ? 170.900 179.893 163.189 1.00 157.87 ? 99  SER C CB  1 
ATOM 3149 O OG  . SER B 2 93  ? 170.138 178.911 163.869 1.00 157.87 ? 99  SER C OG  1 
ATOM 3150 N N   . LYS B 2 94  ? 170.978 182.268 165.279 1.00 154.33 ? 100 LYS C N   1 
ATOM 3151 C CA  . LYS B 2 94  ? 170.492 182.966 166.462 1.00 154.33 ? 100 LYS C CA  1 
ATOM 3152 C C   . LYS B 2 94  ? 169.193 182.385 167.001 1.00 154.33 ? 100 LYS C C   1 
ATOM 3153 O O   . LYS B 2 94  ? 168.837 182.661 168.151 1.00 154.33 ? 100 LYS C O   1 
ATOM 3154 C CB  . LYS B 2 94  ? 170.320 184.454 166.152 1.00 154.33 ? 100 LYS C CB  1 
ATOM 3155 C CG  . LYS B 2 94  ? 169.258 184.752 165.112 1.00 154.33 ? 100 LYS C CG  1 
ATOM 3156 C CD  . LYS B 2 94  ? 169.248 186.226 164.746 1.00 154.33 ? 100 LYS C CD  1 
ATOM 3157 C CE  . LYS B 2 94  ? 168.407 186.479 163.512 1.00 154.33 ? 100 LYS C CE  1 
ATOM 3158 N NZ  . LYS B 2 94  ? 166.975 186.161 163.752 1.00 154.33 ? 100 LYS C NZ  1 
ATOM 3159 N N   . GLU B 2 95  ? 168.474 181.597 166.203 1.00 171.76 ? 101 GLU C N   1 
ATOM 3160 C CA  . GLU B 2 95  ? 167.210 181.030 166.657 1.00 171.76 ? 101 GLU C CA  1 
ATOM 3161 C C   . GLU B 2 95  ? 167.409 179.814 167.557 1.00 171.76 ? 101 GLU C C   1 
ATOM 3162 O O   . GLU B 2 95  ? 166.527 179.500 168.367 1.00 171.76 ? 101 GLU C O   1 
ATOM 3163 C CB  . GLU B 2 95  ? 166.354 180.646 165.452 1.00 171.76 ? 101 GLU C CB  1 
ATOM 3164 C CG  . GLU B 2 95  ? 167.159 179.998 164.340 1.00 171.76 ? 101 GLU C CG  1 
ATOM 3165 C CD  . GLU B 2 95  ? 167.662 180.992 163.318 1.00 171.76 ? 101 GLU C CD  1 
ATOM 3166 O OE1 . GLU B 2 95  ? 168.303 181.984 163.722 1.00 171.76 ? 101 GLU C OE1 1 
ATOM 3167 O OE2 . GLU B 2 95  ? 167.433 180.766 162.110 1.00 171.76 ? 101 GLU C OE2 1 
ATOM 3168 N N   . ASN B 2 96  ? 168.542 179.121 167.425 1.00 166.18 ? 102 ASN C N   1 
ATOM 3169 C CA  . ASN B 2 96  ? 168.794 177.834 168.082 1.00 166.18 ? 102 ASN C CA  1 
ATOM 3170 C C   . ASN B 2 96  ? 170.111 177.832 168.865 1.00 166.18 ? 102 ASN C C   1 
ATOM 3171 O O   . ASN B 2 96  ? 171.102 177.225 168.454 1.00 166.18 ? 102 ASN C O   1 
ATOM 3172 C CB  . ASN B 2 96  ? 168.739 176.721 167.021 1.00 166.18 ? 102 ASN C CB  1 
ATOM 3173 C CG  . ASN B 2 96  ? 169.818 176.852 165.946 1.00 166.18 ? 102 ASN C CG  1 
ATOM 3174 O OD1 . ASN B 2 96  ? 170.705 177.698 166.021 1.00 166.18 ? 102 ASN C OD1 1 
ATOM 3175 N ND2 . ASN B 2 96  ? 169.737 175.998 164.937 1.00 166.18 ? 102 ASN C ND2 1 
ATOM 3176 N N   . VAL B 2 97  ? 170.112 178.460 170.042 1.00 190.14 ? 103 VAL C N   1 
ATOM 3177 C CA  . VAL B 2 97  ? 171.314 178.575 170.856 1.00 190.14 ? 103 VAL C CA  1 
ATOM 3178 C C   . VAL B 2 97  ? 171.116 178.029 172.265 1.00 190.14 ? 103 VAL C C   1 
ATOM 3179 O O   . VAL B 2 97  ? 171.982 177.317 172.781 1.00 190.14 ? 103 VAL C O   1 
ATOM 3180 C CB  . VAL B 2 97  ? 171.823 180.027 170.904 1.00 190.14 ? 103 VAL C CB  1 
ATOM 3181 C CG1 . VAL B 2 97  ? 173.007 180.135 171.845 1.00 190.14 ? 103 VAL C CG1 1 
ATOM 3182 C CG2 . VAL B 2 97  ? 172.235 180.468 169.515 1.00 190.14 ? 103 VAL C CG2 1 
ATOM 3183 N N   . ASP B 2 98  ? 169.982 178.339 172.899 1.00 213.66 ? 104 ASP C N   1 
ATOM 3184 C CA  . ASP B 2 98  ? 169.833 178.120 174.339 1.00 213.66 ? 104 ASP C CA  1 
ATOM 3185 C C   . ASP B 2 98  ? 170.059 176.663 174.732 1.00 213.66 ? 104 ASP C C   1 
ATOM 3186 O O   . ASP B 2 98  ? 170.674 176.382 175.768 1.00 213.66 ? 104 ASP C O   1 
ATOM 3187 C CB  . ASP B 2 98  ? 168.446 178.579 174.783 1.00 213.66 ? 104 ASP C CB  1 
ATOM 3188 C CG  . ASP B 2 98  ? 167.354 178.097 173.852 1.00 213.66 ? 104 ASP C CG  1 
ATOM 3189 O OD1 . ASP B 2 98  ? 167.693 177.626 172.746 1.00 213.66 ? 104 ASP C OD1 1 
ATOM 3190 O OD2 . ASP B 2 98  ? 166.163 178.201 174.212 1.00 213.66 ? 104 ASP C OD2 1 
ATOM 3191 N N   . GLU B 2 99  ? 169.565 175.721 173.928 1.00 190.65 ? 105 GLU C N   1 
ATOM 3192 C CA  . GLU B 2 99  ? 169.714 174.311 174.271 1.00 190.65 ? 105 GLU C CA  1 
ATOM 3193 C C   . GLU B 2 99  ? 171.143 173.809 174.108 1.00 190.65 ? 105 GLU C C   1 
ATOM 3194 O O   . GLU B 2 99  ? 171.428 172.679 174.517 1.00 190.65 ? 105 GLU C O   1 
ATOM 3195 C CB  . GLU B 2 99  ? 168.768 173.463 173.422 1.00 190.65 ? 105 GLU C CB  1 
ATOM 3196 C CG  . GLU B 2 99  ? 169.320 173.127 172.057 1.00 190.65 ? 105 GLU C CG  1 
ATOM 3197 C CD  . GLU B 2 99  ? 168.938 174.143 171.007 1.00 190.65 ? 105 GLU C CD  1 
ATOM 3198 O OE1 . GLU B 2 99  ? 168.471 175.240 171.377 1.00 190.65 ? 105 GLU C OE1 1 
ATOM 3199 O OE2 . GLU B 2 99  ? 169.120 173.850 169.809 1.00 190.65 ? 105 GLU C OE2 1 
ATOM 3200 N N   . VAL B 2 100 ? 172.040 174.606 173.526 1.00 202.92 ? 106 VAL C N   1 
ATOM 3201 C CA  . VAL B 2 100 ? 173.418 174.192 173.278 1.00 202.92 ? 106 VAL C CA  1 
ATOM 3202 C C   . VAL B 2 100 ? 174.342 175.138 174.040 1.00 202.92 ? 106 VAL C C   1 
ATOM 3203 O O   . VAL B 2 100 ? 175.467 175.414 173.616 1.00 202.92 ? 106 VAL C O   1 
ATOM 3204 C CB  . VAL B 2 100 ? 173.724 174.191 171.763 1.00 202.92 ? 106 VAL C CB  1 
ATOM 3205 C CG1 . VAL B 2 100 ? 175.066 173.518 171.442 1.00 202.92 ? 106 VAL C CG1 1 
ATOM 3206 C CG2 . VAL B 2 100 ? 172.597 173.537 170.983 1.00 202.92 ? 106 VAL C CG2 1 
ATOM 3207 N N   . CYS B 2 101 ? 173.879 175.641 175.177 1.00 233.51 ? 107 CYS C N   1 
ATOM 3208 C CA  . CYS B 2 101 ? 174.545 176.756 175.850 1.00 233.51 ? 107 CYS C CA  1 
ATOM 3209 C C   . CYS B 2 101 ? 175.493 176.255 176.940 1.00 233.51 ? 107 CYS C C   1 
ATOM 3210 O O   . CYS B 2 101 ? 175.368 176.585 178.119 1.00 233.51 ? 107 CYS C O   1 
ATOM 3211 C CB  . CYS B 2 101 ? 173.499 177.716 176.417 1.00 233.51 ? 107 CYS C CB  1 
ATOM 3212 S SG  . CYS B 2 101 ? 174.044 179.297 177.165 1.00 233.51 ? 107 CYS C SG  1 
ATOM 3213 N N   . LYS B 2 102 ? 176.444 175.413 176.543 1.00 230.59 ? 108 LYS C N   1 
ATOM 3214 C CA  . LYS B 2 102 ? 177.577 175.108 177.414 1.00 230.59 ? 108 LYS C CA  1 
ATOM 3215 C C   . LYS B 2 102 ? 178.895 174.922 176.668 1.00 230.59 ? 108 LYS C C   1 
ATOM 3216 O O   . LYS B 2 102 ? 179.944 174.852 177.321 1.00 230.59 ? 108 LYS C O   1 
ATOM 3217 C CB  . LYS B 2 102 ? 177.280 173.855 178.249 1.00 230.59 ? 108 LYS C CB  1 
ATOM 3218 C CG  . LYS B 2 102 ? 178.198 173.653 179.444 1.00 230.59 ? 108 LYS C CG  1 
ATOM 3219 C CD  . LYS B 2 102 ? 178.342 174.923 180.258 1.00 230.59 ? 108 LYS C CD  1 
ATOM 3220 C CE  . LYS B 2 102 ? 178.659 174.599 181.707 1.00 230.59 ? 108 LYS C CE  1 
ATOM 3221 N NZ  . LYS B 2 102 ? 179.505 173.381 181.833 1.00 230.59 ? 108 LYS C NZ  1 
ATOM 3222 N N   . CYS B 2 103 ? 178.863 174.808 175.331 1.00 259.86 ? 109 CYS C N   1 
ATOM 3223 C CA  . CYS B 2 103 ? 179.935 174.408 174.412 1.00 259.86 ? 109 CYS C CA  1 
ATOM 3224 C C   . CYS B 2 103 ? 180.433 172.999 174.728 1.00 259.86 ? 109 CYS C C   1 
ATOM 3225 O O   . CYS B 2 103 ? 181.350 172.500 174.071 1.00 259.86 ? 109 CYS C O   1 
ATOM 3226 C CB  . CYS B 2 103 ? 181.122 175.397 174.372 1.00 259.86 ? 109 CYS C CB  1 
ATOM 3227 S SG  . CYS B 2 103 ? 182.167 175.661 175.812 1.00 259.86 ? 109 CYS C SG  1 
ATOM 3228 N N   . VAL B 2 104 ? 179.833 172.346 175.721 1.00 256.51 ? 110 VAL C N   1 
ATOM 3229 C CA  . VAL B 2 104 ? 179.902 170.897 175.852 1.00 256.51 ? 110 VAL C CA  1 
ATOM 3230 C C   . VAL B 2 104 ? 178.540 170.400 175.383 1.00 256.51 ? 110 VAL C C   1 
ATOM 3231 O O   . VAL B 2 104 ? 178.140 169.260 175.648 1.00 256.51 ? 110 VAL C O   1 
ATOM 3232 C CB  . VAL B 2 104 ? 180.243 170.451 177.287 1.00 256.51 ? 110 VAL C CB  1 
ATOM 3233 C CG1 . VAL B 2 104 ? 179.046 170.562 178.212 1.00 256.51 ? 110 VAL C CG1 1 
ATOM 3234 C CG2 . VAL B 2 104 ? 180.819 169.049 177.281 1.00 256.51 ? 110 VAL C CG2 1 
ATOM 3235 N N   . GLU B 2 105 ? 177.809 171.311 174.734 1.00 242.49 ? 111 GLU C N   1 
ATOM 3236 C CA  . GLU B 2 105 ? 176.631 171.128 173.887 1.00 242.49 ? 111 GLU C CA  1 
ATOM 3237 C C   . GLU B 2 105 ? 175.397 170.634 174.635 1.00 242.49 ? 111 GLU C C   1 
ATOM 3238 O O   . GLU B 2 105 ? 174.297 170.685 174.084 1.00 242.49 ? 111 GLU C O   1 
ATOM 3239 C CB  . GLU B 2 105 ? 176.960 170.237 172.673 1.00 242.49 ? 111 GLU C CB  1 
ATOM 3240 C CG  . GLU B 2 105 ? 177.333 168.783 172.900 1.00 242.49 ? 111 GLU C CG  1 
ATOM 3241 C CD  . GLU B 2 105 ? 178.839 168.557 172.804 1.00 242.49 ? 111 GLU C CD  1 
ATOM 3242 O OE1 . GLU B 2 105 ? 179.599 169.550 172.779 1.00 242.49 ? 111 GLU C OE1 1 
ATOM 3243 O OE2 . GLU B 2 105 ? 179.264 167.385 172.768 1.00 242.49 ? 111 GLU C OE2 1 
ATOM 3244 N N   . PHE B 2 106 ? 175.551 170.252 175.904 1.00 240.76 ? 112 PHE C N   1 
ATOM 3245 C CA  . PHE B 2 106 ? 174.473 170.307 176.890 1.00 240.76 ? 112 PHE C CA  1 
ATOM 3246 C C   . PHE B 2 106 ? 173.093 169.923 176.361 1.00 240.76 ? 112 PHE C C   1 
ATOM 3247 O O   . PHE B 2 106 ? 172.112 170.621 176.628 1.00 240.76 ? 112 PHE C O   1 
ATOM 3248 C CB  . PHE B 2 106 ? 174.432 171.732 177.450 1.00 240.76 ? 112 PHE C CB  1 
ATOM 3249 C CG  . PHE B 2 106 ? 173.808 171.853 178.810 1.00 240.76 ? 112 PHE C CG  1 
ATOM 3250 C CD1 . PHE B 2 106 ? 174.398 171.281 179.924 1.00 240.76 ? 112 PHE C CD1 1 
ATOM 3251 C CD2 . PHE B 2 106 ? 172.649 172.593 178.978 1.00 240.76 ? 112 PHE C CD2 1 
ATOM 3252 C CE1 . PHE B 2 106 ? 173.822 171.419 181.174 1.00 240.76 ? 112 PHE C CE1 1 
ATOM 3253 C CE2 . PHE B 2 106 ? 172.071 172.733 180.222 1.00 240.76 ? 112 PHE C CE2 1 
ATOM 3254 C CZ  . PHE B 2 106 ? 172.657 172.147 181.321 1.00 240.76 ? 112 PHE C CZ  1 
ATOM 3255 N N   . LEU B 2 107 ? 172.987 168.818 175.621 1.00 213.28 ? 113 LEU C N   1 
ATOM 3256 C CA  . LEU B 2 107 ? 171.698 168.409 175.059 1.00 213.28 ? 113 LEU C CA  1 
ATOM 3257 C C   . LEU B 2 107 ? 170.819 167.851 176.174 1.00 213.28 ? 113 LEU C C   1 
ATOM 3258 O O   . LEU B 2 107 ? 170.764 166.646 176.429 1.00 213.28 ? 113 LEU C O   1 
ATOM 3259 C CB  . LEU B 2 107 ? 171.859 167.384 173.942 1.00 213.28 ? 113 LEU C CB  1 
ATOM 3260 C CG  . LEU B 2 107 ? 172.157 167.835 172.511 1.00 213.28 ? 113 LEU C CG  1 
ATOM 3261 C CD1 . LEU B 2 107 ? 171.025 168.698 171.972 1.00 213.28 ? 113 LEU C CD1 1 
ATOM 3262 C CD2 . LEU B 2 107 ? 173.501 168.512 172.367 1.00 213.28 ? 113 LEU C CD2 1 
ATOM 3263 N N   . SER B 2 108 ? 170.132 168.766 176.851 1.00 220.54 ? 114 SER C N   1 
ATOM 3264 C CA  . SER B 2 108 ? 169.111 168.458 177.845 1.00 220.54 ? 114 SER C CA  1 
ATOM 3265 C C   . SER B 2 108 ? 169.683 167.916 179.149 1.00 220.54 ? 114 SER C C   1 
ATOM 3266 O O   . SER B 2 108 ? 169.910 168.693 180.082 1.00 220.54 ? 114 SER C O   1 
ATOM 3267 C CB  . SER B 2 108 ? 168.087 167.475 177.276 1.00 220.54 ? 114 SER C CB  1 
ATOM 3268 O OG  . SER B 2 108 ? 167.436 168.032 176.151 1.00 220.54 ? 114 SER C OG  1 
ATOM 3269 N N   . VAL B 2 109 ? 169.930 166.604 179.239 1.00 222.99 ? 115 VAL C N   1 
ATOM 3270 C CA  . VAL B 2 109 ? 170.062 165.996 180.564 1.00 222.99 ? 115 VAL C CA  1 
ATOM 3271 C C   . VAL B 2 109 ? 171.303 166.514 181.305 1.00 222.99 ? 115 VAL C C   1 
ATOM 3272 O O   . VAL B 2 109 ? 171.193 166.932 182.465 1.00 222.99 ? 115 VAL C O   1 
ATOM 3273 C CB  . VAL B 2 109 ? 169.945 164.455 180.495 1.00 222.99 ? 115 VAL C CB  1 
ATOM 3274 C CG1 . VAL B 2 109 ? 168.538 164.086 180.076 1.00 222.99 ? 115 VAL C CG1 1 
ATOM 3275 C CG2 . VAL B 2 109 ? 170.834 163.830 179.452 1.00 222.99 ? 115 VAL C CG2 1 
ATOM 3276 N N   . HIS B 2 110 ? 172.491 166.531 180.683 1.00 191.80 ? 116 HIS C N   1 
ATOM 3277 C CA  . HIS B 2 110 ? 173.275 165.821 179.674 1.00 191.80 ? 116 HIS C CA  1 
ATOM 3278 C C   . HIS B 2 110 ? 174.740 165.846 180.100 1.00 191.80 ? 116 HIS C C   1 
ATOM 3279 O O   . HIS B 2 110 ? 175.640 165.992 179.271 1.00 191.80 ? 116 HIS C O   1 
ATOM 3280 C CB  . HIS B 2 110 ? 173.111 166.419 178.287 1.00 191.80 ? 116 HIS C CB  1 
ATOM 3281 C CG  . HIS B 2 110 ? 173.719 165.582 177.205 1.00 191.80 ? 116 HIS C CG  1 
ATOM 3282 N ND1 . HIS B 2 110 ? 175.075 165.554 176.965 1.00 191.80 ? 116 HIS C ND1 1 
ATOM 3283 C CD2 . HIS B 2 110 ? 173.164 164.714 176.330 1.00 191.80 ? 116 HIS C CD2 1 
ATOM 3284 C CE1 . HIS B 2 110 ? 175.326 164.724 175.971 1.00 191.80 ? 116 HIS C CE1 1 
ATOM 3285 N NE2 . HIS B 2 110 ? 174.184 164.200 175.567 1.00 191.80 ? 116 HIS C NE2 1 
ATOM 3286 N N   . ASN B 2 111 ? 174.974 165.710 181.404 1.00 189.64 ? 117 ASN C N   1 
ATOM 3287 C CA  . ASN B 2 111 ? 176.311 165.880 181.963 1.00 189.64 ? 117 ASN C CA  1 
ATOM 3288 C C   . ASN B 2 111 ? 177.216 164.770 181.451 1.00 189.64 ? 117 ASN C C   1 
ATOM 3289 O O   . ASN B 2 111 ? 176.929 163.584 181.640 1.00 189.64 ? 117 ASN C O   1 
ATOM 3290 C CB  . ASN B 2 111 ? 176.252 165.885 183.488 1.00 189.64 ? 117 ASN C CB  1 
ATOM 3291 C CG  . ASN B 2 111 ? 177.190 166.906 184.103 1.00 189.64 ? 117 ASN C CG  1 
ATOM 3292 O OD1 . ASN B 2 111 ? 177.189 168.075 183.719 1.00 189.64 ? 117 ASN C OD1 1 
ATOM 3293 N ND2 . ASN B 2 111 ? 177.995 166.468 185.064 1.00 189.64 ? 117 ASN C ND2 1 
ATOM 3294 N N   . ILE B 2 112 ? 178.311 165.152 180.804 1.00 187.85 ? 118 ILE C N   1 
ATOM 3295 C CA  . ILE B 2 112 ? 179.193 164.185 180.174 1.00 187.85 ? 118 ILE C CA  1 
ATOM 3296 C C   . ILE B 2 112 ? 179.966 163.426 181.241 1.00 187.85 ? 118 ILE C C   1 
ATOM 3297 O O   . ILE B 2 112 ? 180.132 163.908 182.360 1.00 187.85 ? 118 ILE C O   1 
ATOM 3298 C CB  . ILE B 2 112 ? 180.149 164.861 179.193 1.00 187.85 ? 118 ILE C CB  1 
ATOM 3299 C CG1 . ILE B 2 112 ? 181.051 165.842 179.935 1.00 187.85 ? 118 ILE C CG1 1 
ATOM 3300 C CG2 . ILE B 2 112 ? 179.365 165.612 178.130 1.00 187.85 ? 118 ILE C CG2 1 
ATOM 3301 C CD1 . ILE B 2 112 ? 182.175 166.374 179.089 1.00 187.85 ? 118 ILE C CD1 1 
ATOM 3302 N N   . LYS C 1 54  ? 201.730 226.397 167.995 1.00 572.00 ? 363 LYS H N   1 
ATOM 3303 C CA  . LYS C 1 54  ? 200.538 227.072 168.494 1.00 572.00 ? 363 LYS H CA  1 
ATOM 3304 C C   . LYS C 1 54  ? 199.319 226.154 168.453 1.00 572.00 ? 363 LYS H C   1 
ATOM 3305 O O   . LYS C 1 54  ? 198.440 226.237 169.311 1.00 572.00 ? 363 LYS H O   1 
ATOM 3306 C CB  . LYS C 1 54  ? 200.265 228.345 167.688 1.00 572.00 ? 363 LYS H CB  1 
ATOM 3307 C CG  . LYS C 1 54  ? 199.989 228.110 166.210 1.00 572.00 ? 363 LYS H CG  1 
ATOM 3308 C CD  . LYS C 1 54  ? 200.189 229.376 165.395 1.00 572.00 ? 363 LYS H CD  1 
ATOM 3309 C CE  . LYS C 1 54  ? 198.989 230.302 165.516 1.00 572.00 ? 363 LYS H CE  1 
ATOM 3310 N NZ  . LYS C 1 54  ? 199.352 231.719 165.244 1.00 572.00 ? 363 LYS H NZ  1 
ATOM 3311 N N   . GLN C 1 55  ? 199.270 225.284 167.445 1.00 533.69 ? 364 GLN H N   1 
ATOM 3312 C CA  . GLN C 1 55  ? 198.170 224.336 167.283 1.00 533.69 ? 364 GLN H CA  1 
ATOM 3313 C C   . GLN C 1 55  ? 198.781 223.023 166.816 1.00 533.69 ? 364 GLN H C   1 
ATOM 3314 O O   . GLN C 1 55  ? 198.996 222.840 165.613 1.00 533.69 ? 364 GLN H O   1 
ATOM 3315 C CB  . GLN C 1 55  ? 197.139 224.843 166.275 1.00 533.69 ? 364 GLN H CB  1 
ATOM 3316 C CG  . GLN C 1 55  ? 196.487 226.168 166.631 1.00 533.69 ? 364 GLN H CG  1 
ATOM 3317 C CD  . GLN C 1 55  ? 195.586 226.065 167.840 1.00 533.69 ? 364 GLN H CD  1 
ATOM 3318 O OE1 . GLN C 1 55  ? 194.498 225.493 167.772 1.00 533.69 ? 364 GLN H OE1 1 
ATOM 3319 N NE2 . GLN C 1 55  ? 196.033 226.623 168.959 1.00 533.69 ? 364 GLN H NE2 1 
ATOM 3320 N N   . LEU C 1 56  ? 199.063 222.117 167.752 1.00 482.96 ? 365 LEU H N   1 
ATOM 3321 C CA  . LEU C 1 56  ? 199.697 220.862 167.366 1.00 482.96 ? 365 LEU H CA  1 
ATOM 3322 C C   . LEU C 1 56  ? 198.680 219.884 166.791 1.00 482.96 ? 365 LEU H C   1 
ATOM 3323 O O   . LEU C 1 56  ? 198.724 219.560 165.600 1.00 482.96 ? 365 LEU H O   1 
ATOM 3324 C CB  . LEU C 1 56  ? 200.428 220.247 168.561 1.00 482.96 ? 365 LEU H CB  1 
ATOM 3325 C CG  . LEU C 1 56  ? 201.798 220.853 168.861 1.00 482.96 ? 365 LEU H CG  1 
ATOM 3326 C CD1 . LEU C 1 56  ? 202.591 219.946 169.786 1.00 482.96 ? 365 LEU H CD1 1 
ATOM 3327 C CD2 . LEU C 1 56  ? 202.552 221.101 167.568 1.00 482.96 ? 365 LEU H CD2 1 
ATOM 3328 N N   . ASP C 1 57  ? 197.735 219.434 167.616 1.00 430.05 ? 366 ASP H N   1 
ATOM 3329 C CA  . ASP C 1 57  ? 196.716 218.469 167.207 1.00 430.05 ? 366 ASP H CA  1 
ATOM 3330 C C   . ASP C 1 57  ? 197.352 217.300 166.460 1.00 430.05 ? 366 ASP H C   1 
ATOM 3331 O O   . ASP C 1 57  ? 196.903 216.878 165.394 1.00 430.05 ? 366 ASP H O   1 
ATOM 3332 C CB  . ASP C 1 57  ? 195.634 219.138 166.360 1.00 430.05 ? 366 ASP H CB  1 
ATOM 3333 C CG  . ASP C 1 57  ? 194.327 218.372 166.383 1.00 430.05 ? 366 ASP H CG  1 
ATOM 3334 O OD1 . ASP C 1 57  ? 194.330 217.203 166.826 1.00 430.05 ? 366 ASP H OD1 1 
ATOM 3335 O OD2 . ASP C 1 57  ? 193.296 218.942 165.970 1.00 430.05 ? 366 ASP H OD2 1 
ATOM 3336 N N   . LEU C 1 58  ? 198.426 216.781 167.051 1.00 396.53 ? 367 LEU H N   1 
ATOM 3337 C CA  . LEU C 1 58  ? 199.292 215.803 166.408 1.00 396.53 ? 367 LEU H CA  1 
ATOM 3338 C C   . LEU C 1 58  ? 198.783 214.374 166.592 1.00 396.53 ? 367 LEU H C   1 
ATOM 3339 O O   . LEU C 1 58  ? 199.558 213.416 166.520 1.00 396.53 ? 367 LEU H O   1 
ATOM 3340 C CB  . LEU C 1 58  ? 200.721 216.000 166.930 1.00 396.53 ? 367 LEU H CB  1 
ATOM 3341 C CG  . LEU C 1 58  ? 202.031 215.351 166.470 1.00 396.53 ? 367 LEU H CG  1 
ATOM 3342 C CD1 . LEU C 1 58  ? 203.129 216.330 166.796 1.00 396.53 ? 367 LEU H CD1 1 
ATOM 3343 C CD2 . LEU C 1 58  ? 202.339 214.058 167.204 1.00 396.53 ? 367 LEU H CD2 1 
ATOM 3344 N N   . SER C 1 59  ? 197.480 214.215 166.801 1.00 376.20 ? 368 SER H N   1 
ATOM 3345 C CA  . SER C 1 59  ? 196.895 212.898 167.009 1.00 376.20 ? 368 SER H CA  1 
ATOM 3346 C C   . SER C 1 59  ? 197.063 212.018 165.775 1.00 376.20 ? 368 SER H C   1 
ATOM 3347 O O   . SER C 1 59  ? 197.078 212.505 164.640 1.00 376.20 ? 368 SER H O   1 
ATOM 3348 C CB  . SER C 1 59  ? 195.412 213.029 167.356 1.00 376.20 ? 368 SER H CB  1 
ATOM 3349 O OG  . SER C 1 59  ? 194.693 213.677 166.323 1.00 376.20 ? 368 SER H OG  1 
ATOM 3350 N N   . SER C 1 60  ? 197.206 210.711 166.012 1.00 366.58 ? 369 SER H N   1 
ATOM 3351 C CA  . SER C 1 60  ? 197.310 209.712 164.949 1.00 366.58 ? 369 SER H CA  1 
ATOM 3352 C C   . SER C 1 60  ? 198.455 210.037 163.990 1.00 366.58 ? 369 SER H C   1 
ATOM 3353 O O   . SER C 1 60  ? 198.365 209.826 162.780 1.00 366.58 ? 369 SER H O   1 
ATOM 3354 C CB  . SER C 1 60  ? 195.982 209.576 164.196 1.00 366.58 ? 369 SER H CB  1 
ATOM 3355 O OG  . SER C 1 60  ? 196.046 208.552 163.220 1.00 366.58 ? 369 SER H OG  1 
ATOM 3356 N N   . ARG C 1 61  ? 199.547 210.555 164.546 1.00 389.61 ? 370 ARG H N   1 
ATOM 3357 C CA  . ARG C 1 61  ? 200.714 210.913 163.758 1.00 389.61 ? 370 ARG H CA  1 
ATOM 3358 C C   . ARG C 1 61  ? 201.708 209.765 163.642 1.00 389.61 ? 370 ARG H C   1 
ATOM 3359 O O   . ARG C 1 61  ? 202.666 209.868 162.869 1.00 389.61 ? 370 ARG H O   1 
ATOM 3360 C CB  . ARG C 1 61  ? 201.403 212.136 164.368 1.00 389.61 ? 370 ARG H CB  1 
ATOM 3361 C CG  . ARG C 1 61  ? 201.566 213.325 163.426 1.00 389.61 ? 370 ARG H CG  1 
ATOM 3362 C CD  . ARG C 1 61  ? 200.298 214.182 163.406 1.00 389.61 ? 370 ARG H CD  1 
ATOM 3363 N NE  . ARG C 1 61  ? 200.412 215.351 162.539 1.00 389.61 ? 370 ARG H NE  1 
ATOM 3364 C CZ  . ARG C 1 61  ? 199.388 216.097 162.149 1.00 389.61 ? 370 ARG H CZ  1 
ATOM 3365 N N   . GLN C 1 62  ? 201.485 208.676 164.381 1.00 393.27 ? 371 GLN H N   1 
ATOM 3366 C CA  . GLN C 1 62  ? 202.328 207.484 164.397 1.00 393.27 ? 371 GLN H CA  1 
ATOM 3367 C C   . GLN C 1 62  ? 203.820 207.807 164.416 1.00 393.27 ? 371 GLN H C   1 
ATOM 3368 O O   . GLN C 1 62  ? 204.256 208.697 165.153 1.00 393.27 ? 371 GLN H O   1 
ATOM 3369 C CB  . GLN C 1 62  ? 201.990 206.600 163.197 1.00 393.27 ? 371 GLN H CB  1 
ATOM 3370 C CG  . GLN C 1 62  ? 200.494 206.449 162.965 1.00 393.27 ? 371 GLN H CG  1 
ATOM 3371 C CD  . GLN C 1 62  ? 199.774 205.796 164.129 1.00 393.27 ? 371 GLN H CD  1 
ATOM 3372 O OE1 . GLN C 1 62  ? 200.359 205.026 164.891 1.00 393.27 ? 371 GLN H OE1 1 
ATOM 3373 N NE2 . GLN C 1 62  ? 198.492 206.108 164.274 1.00 393.27 ? 371 GLN H NE2 1 
ATOM 3374 N N   . GLN C 1 63  ? 204.607 207.101 163.608 1.00 396.73 ? 372 GLN H N   1 
ATOM 3375 C CA  . GLN C 1 63  ? 206.061 207.278 163.593 1.00 396.73 ? 372 GLN H CA  1 
ATOM 3376 C C   . GLN C 1 63  ? 206.504 208.314 162.566 1.00 396.73 ? 372 GLN H C   1 
ATOM 3377 O O   . GLN C 1 63  ? 207.246 208.018 161.631 1.00 396.73 ? 372 GLN H O   1 
ATOM 3378 C CB  . GLN C 1 63  ? 206.756 205.944 163.351 1.00 396.73 ? 372 GLN H CB  1 
ATOM 3379 C CG  . GLN C 1 63  ? 206.834 205.050 164.573 1.00 396.73 ? 372 GLN H CG  1 
ATOM 3380 C CD  . GLN C 1 63  ? 205.576 204.248 164.795 1.00 396.73 ? 372 GLN H CD  1 
ATOM 3381 O OE1 . GLN C 1 63  ? 205.025 203.664 163.863 1.00 396.73 ? 372 GLN H OE1 1 
ATOM 3382 N NE2 . GLN C 1 63  ? 205.108 204.216 166.037 1.00 396.73 ? 372 GLN H NE2 1 
ATOM 3383 N N   . VAL C 1 64  ? 206.054 209.551 162.747 1.00 399.59 ? 373 VAL H N   1 
ATOM 3384 C CA  . VAL C 1 64  ? 206.529 210.664 161.935 1.00 399.59 ? 373 VAL H CA  1 
ATOM 3385 C C   . VAL C 1 64  ? 207.242 211.640 162.862 1.00 399.59 ? 373 VAL H C   1 
ATOM 3386 O O   . VAL C 1 64  ? 208.134 212.385 162.438 1.00 399.59 ? 373 VAL H O   1 
ATOM 3387 C CB  . VAL C 1 64  ? 205.371 211.339 161.171 1.00 399.59 ? 373 VAL H CB  1 
ATOM 3388 C CG1 . VAL C 1 64  ? 205.875 212.498 160.322 1.00 399.59 ? 373 VAL H CG1 1 
ATOM 3389 C CG2 . VAL C 1 64  ? 204.644 210.321 160.304 1.00 399.59 ? 373 VAL H CG2 1 
ATOM 3390 N N   . THR C 1 65  ? 206.876 211.614 164.143 1.00 411.25 ? 374 THR H N   1 
ATOM 3391 C CA  . THR C 1 65  ? 207.321 212.602 165.125 1.00 411.25 ? 374 THR H CA  1 
ATOM 3392 C C   . THR C 1 65  ? 207.985 211.893 166.303 1.00 411.25 ? 374 THR H C   1 
ATOM 3393 O O   . THR C 1 65  ? 207.297 211.327 167.156 1.00 411.25 ? 374 THR H O   1 
ATOM 3394 C CB  . THR C 1 65  ? 206.141 213.443 165.604 1.00 411.25 ? 374 THR H CB  1 
ATOM 3395 O OG1 . THR C 1 65  ? 205.126 212.580 166.133 1.00 411.25 ? 374 THR H OG1 1 
ATOM 3396 C CG2 . THR C 1 65  ? 205.553 214.241 164.451 1.00 411.25 ? 374 THR H CG2 1 
ATOM 3397 N N   . ASP C 1 66  ? 209.316 211.937 166.368 1.00 399.04 ? 375 ASP H N   1 
ATOM 3398 C CA  . ASP C 1 66  ? 210.037 211.421 167.527 1.00 399.04 ? 375 ASP H CA  1 
ATOM 3399 C C   . ASP C 1 66  ? 210.893 212.481 168.202 1.00 399.04 ? 375 ASP H C   1 
ATOM 3400 O O   . ASP C 1 66  ? 210.956 212.525 169.436 1.00 399.04 ? 375 ASP H O   1 
ATOM 3401 C CB  . ASP C 1 66  ? 210.911 210.217 167.135 1.00 399.04 ? 375 ASP H CB  1 
ATOM 3402 C CG  . ASP C 1 66  ? 211.835 210.518 165.975 1.00 399.04 ? 375 ASP H CG  1 
ATOM 3403 O OD1 . ASP C 1 66  ? 211.759 211.636 165.426 1.00 399.04 ? 375 ASP H OD1 1 
ATOM 3404 O OD2 . ASP C 1 66  ? 212.645 209.637 165.619 1.00 399.04 ? 375 ASP H OD2 1 
ATOM 3405 N N   . GLU C 1 67  ? 211.568 213.331 167.428 1.00 450.59 ? 376 GLU H N   1 
ATOM 3406 C CA  . GLU C 1 67  ? 212.416 214.382 167.974 1.00 450.59 ? 376 GLU H CA  1 
ATOM 3407 C C   . GLU C 1 67  ? 212.213 215.734 167.307 1.00 450.59 ? 376 GLU H C   1 
ATOM 3408 O O   . GLU C 1 67  ? 212.928 216.685 167.645 1.00 450.59 ? 376 GLU H O   1 
ATOM 3409 C CB  . GLU C 1 67  ? 213.896 213.987 167.858 1.00 450.59 ? 376 GLU H CB  1 
ATOM 3410 C CG  . GLU C 1 67  ? 214.338 213.627 166.441 1.00 450.59 ? 376 GLU H CG  1 
ATOM 3411 C CD  . GLU C 1 67  ? 214.986 214.789 165.707 1.00 450.59 ? 376 GLU H CD  1 
ATOM 3412 O OE1 . GLU C 1 67  ? 215.471 215.724 166.376 1.00 450.59 ? 376 GLU H OE1 1 
ATOM 3413 O OE2 . GLU C 1 67  ? 215.014 214.764 164.458 1.00 450.59 ? 376 GLU H OE2 1 
ATOM 3414 N N   . LEU C 1 68  ? 211.262 215.852 166.377 1.00 487.75 ? 377 LEU H N   1 
ATOM 3415 C CA  . LEU C 1 68  ? 211.119 217.080 165.602 1.00 487.75 ? 377 LEU H CA  1 
ATOM 3416 C C   . LEU C 1 68  ? 210.522 218.211 166.433 1.00 487.75 ? 377 LEU H C   1 
ATOM 3417 O O   . LEU C 1 68  ? 210.635 219.379 166.044 1.00 487.75 ? 377 LEU H O   1 
ATOM 3418 C CB  . LEU C 1 68  ? 210.270 216.800 164.353 1.00 487.75 ? 377 LEU H CB  1 
ATOM 3419 C CG  . LEU C 1 68  ? 210.282 217.759 163.156 1.00 487.75 ? 377 LEU H CG  1 
ATOM 3420 C CD1 . LEU C 1 68  ? 211.631 217.715 162.460 1.00 487.75 ? 377 LEU H CD1 1 
ATOM 3421 C CD2 . LEU C 1 68  ? 209.175 217.418 162.165 1.00 487.75 ? 377 LEU H CD2 1 
ATOM 3422 N N   . LEU C 1 69  ? 209.922 217.890 167.584 1.00 491.64 ? 378 LEU H N   1 
ATOM 3423 C CA  . LEU C 1 69  ? 209.308 218.885 168.457 1.00 491.64 ? 378 LEU H CA  1 
ATOM 3424 C C   . LEU C 1 69  ? 210.305 219.907 168.988 1.00 491.64 ? 378 LEU H C   1 
ATOM 3425 O O   . LEU C 1 69  ? 209.884 220.973 169.449 1.00 491.64 ? 378 LEU H O   1 
ATOM 3426 C CB  . LEU C 1 69  ? 208.608 218.188 169.630 1.00 491.64 ? 378 LEU H CB  1 
ATOM 3427 C CG  . LEU C 1 69  ? 207.122 217.840 169.480 1.00 491.64 ? 378 LEU H CG  1 
ATOM 3428 C CD1 . LEU C 1 69  ? 206.535 217.408 170.811 1.00 491.64 ? 378 LEU H CD1 1 
ATOM 3429 C CD2 . LEU C 1 69  ? 206.341 219.015 168.924 1.00 491.64 ? 378 LEU H CD2 1 
ATOM 3430 N N   . GLU C 1 70  ? 211.605 219.612 168.938 1.00 488.71 ? 379 GLU H N   1 
ATOM 3431 C CA  . GLU C 1 70  ? 212.607 220.597 169.328 1.00 488.71 ? 379 GLU H CA  1 
ATOM 3432 C C   . GLU C 1 70  ? 212.626 221.799 168.393 1.00 488.71 ? 379 GLU H C   1 
ATOM 3433 O O   . GLU C 1 70  ? 213.214 222.829 168.739 1.00 488.71 ? 379 GLU H O   1 
ATOM 3434 C CB  . GLU C 1 70  ? 213.992 219.949 169.382 1.00 488.71 ? 379 GLU H CB  1 
ATOM 3435 C CG  . GLU C 1 70  ? 214.512 219.454 168.044 1.00 488.71 ? 379 GLU H CG  1 
ATOM 3436 C CD  . GLU C 1 70  ? 215.848 218.743 168.168 1.00 488.71 ? 379 GLU H CD  1 
ATOM 3437 O OE1 . GLU C 1 70  ? 216.360 218.627 169.301 1.00 488.71 ? 379 GLU H OE1 1 
ATOM 3438 O OE2 . GLU C 1 70  ? 216.385 218.301 167.131 1.00 488.71 ? 379 GLU H OE2 1 
ATOM 3439 N N   . LYS C 1 71  ? 212.008 221.689 167.216 1.00 512.97 ? 380 LYS H N   1 
ATOM 3440 C CA  . LYS C 1 71  ? 211.922 222.810 166.290 1.00 512.97 ? 380 LYS H CA  1 
ATOM 3441 C C   . LYS C 1 71  ? 210.622 223.598 166.416 1.00 512.97 ? 380 LYS H C   1 
ATOM 3442 O O   . LYS C 1 71  ? 210.615 224.795 166.110 1.00 512.97 ? 380 LYS H O   1 
ATOM 3443 C CB  . LYS C 1 71  ? 212.103 222.310 164.848 1.00 512.97 ? 380 LYS H CB  1 
ATOM 3444 C CG  . LYS C 1 71  ? 213.179 221.228 164.714 1.00 512.97 ? 380 LYS H CG  1 
ATOM 3445 C CD  . LYS C 1 71  ? 213.302 220.683 163.298 1.00 512.97 ? 380 LYS H CD  1 
ATOM 3446 C CE  . LYS C 1 71  ? 213.494 221.773 162.265 1.00 512.97 ? 380 LYS H CE  1 
ATOM 3447 N NZ  . LYS C 1 71  ? 213.426 221.213 160.886 1.00 512.97 ? 380 LYS H NZ  1 
ATOM 3448 N N   . ILE C 1 72  ? 209.532 222.966 166.859 1.00 529.15 ? 381 ILE H N   1 
ATOM 3449 C CA  . ILE C 1 72  ? 208.291 223.702 167.099 1.00 529.15 ? 381 ILE H CA  1 
ATOM 3450 C C   . ILE C 1 72  ? 208.449 224.682 168.256 1.00 529.15 ? 381 ILE H C   1 
ATOM 3451 O O   . ILE C 1 72  ? 208.006 225.834 168.171 1.00 529.15 ? 381 ILE H O   1 
ATOM 3452 C CB  . ILE C 1 72  ? 207.109 222.738 167.323 1.00 529.15 ? 381 ILE H CB  1 
ATOM 3453 C CG1 . ILE C 1 72  ? 206.837 221.897 166.067 1.00 529.15 ? 381 ILE H CG1 1 
ATOM 3454 C CG2 . ILE C 1 72  ? 205.866 223.501 167.766 1.00 529.15 ? 381 ILE H CG2 1 
ATOM 3455 C CD1 . ILE C 1 72  ? 207.598 220.605 165.966 1.00 529.15 ? 381 ILE H CD1 1 
ATOM 3456 N N   . ALA C 1 73  ? 209.078 224.258 169.347 1.00 512.00 ? 382 ALA H N   1 
ATOM 3457 C CA  . ALA C 1 73  ? 209.255 225.110 170.522 1.00 512.00 ? 382 ALA H CA  1 
ATOM 3458 C C   . ALA C 1 73  ? 210.619 225.784 170.400 1.00 512.00 ? 382 ALA H C   1 
ATOM 3459 O O   . ALA C 1 73  ? 211.572 225.421 171.093 1.00 512.00 ? 382 ALA H O   1 
ATOM 3460 C CB  . ALA C 1 73  ? 209.136 224.307 171.818 1.00 512.00 ? 382 ALA H CB  1 
ATOM 3461 N N   . SER C 1 74  ? 210.701 226.780 169.518 1.00 513.09 ? 383 SER H N   1 
ATOM 3462 C CA  . SER C 1 74  ? 211.927 227.540 169.301 1.00 513.09 ? 383 SER H CA  1 
ATOM 3463 C C   . SER C 1 74  ? 211.774 229.008 169.669 1.00 513.09 ? 383 SER H C   1 
ATOM 3464 O O   . SER C 1 74  ? 212.502 229.502 170.539 1.00 513.09 ? 383 SER H O   1 
ATOM 3465 C CB  . SER C 1 74  ? 212.374 227.403 167.838 1.00 513.09 ? 383 SER H CB  1 
ATOM 3466 O OG  . SER C 1 74  ? 213.275 228.435 167.479 1.00 513.09 ? 383 SER H OG  1 
ATOM 3467 N N   . ARG C 1 75  ? 210.845 229.725 169.032 1.00 488.18 ? 384 ARG H N   1 
ATOM 3468 C CA  . ARG C 1 75  ? 210.433 231.040 169.498 1.00 488.18 ? 384 ARG H CA  1 
ATOM 3469 C C   . ARG C 1 75  ? 209.001 231.059 170.009 1.00 488.18 ? 384 ARG H C   1 
ATOM 3470 O O   . ARG C 1 75  ? 208.605 232.040 170.651 1.00 488.18 ? 384 ARG H O   1 
ATOM 3471 C CB  . ARG C 1 75  ? 210.561 232.105 168.391 1.00 488.18 ? 384 ARG H CB  1 
ATOM 3472 C CG  . ARG C 1 75  ? 211.249 231.672 167.105 1.00 488.18 ? 384 ARG H CG  1 
ATOM 3473 C CD  . ARG C 1 75  ? 211.689 232.884 166.292 1.00 488.18 ? 384 ARG H CD  1 
ATOM 3474 N NE  . ARG C 1 75  ? 211.482 232.674 164.866 1.00 488.18 ? 384 ARG H NE  1 
ATOM 3475 C CZ  . ARG C 1 75  ? 212.109 231.753 164.147 1.00 488.18 ? 384 ARG H CZ  1 
ATOM 3476 N N   . SER C 1 76  ? 208.218 230.017 169.739 1.00 481.93 ? 385 SER H N   1 
ATOM 3477 C CA  . SER C 1 76  ? 206.829 229.999 170.161 1.00 481.93 ? 385 SER H CA  1 
ATOM 3478 C C   . SER C 1 76  ? 206.716 229.633 171.637 1.00 481.93 ? 385 SER H C   1 
ATOM 3479 O O   . SER C 1 76  ? 207.214 228.598 172.091 1.00 481.93 ? 385 SER H O   1 
ATOM 3480 C CB  . SER C 1 76  ? 206.029 229.018 169.304 1.00 481.93 ? 385 SER H CB  1 
ATOM 3481 O OG  . SER C 1 76  ? 206.014 229.429 167.948 1.00 481.93 ? 385 SER H OG  1 
ATOM 3482 N N   . GLN C 1 77  ? 206.032 230.499 172.382 1.00 479.73 ? 386 GLN H N   1 
ATOM 3483 C CA  . GLN C 1 77  ? 205.826 230.332 173.810 1.00 479.73 ? 386 GLN H CA  1 
ATOM 3484 C C   . GLN C 1 77  ? 204.355 230.200 174.167 1.00 479.73 ? 386 GLN H C   1 
ATOM 3485 O O   . GLN C 1 77  ? 204.015 230.247 175.353 1.00 479.73 ? 386 GLN H O   1 
ATOM 3486 C CB  . GLN C 1 77  ? 206.428 231.524 174.576 1.00 479.73 ? 386 GLN H CB  1 
ATOM 3487 C CG  . GLN C 1 77  ? 206.803 231.262 176.027 1.00 479.73 ? 386 GLN H CG  1 
ATOM 3488 C CD  . GLN C 1 77  ? 207.513 232.443 176.666 1.00 479.73 ? 386 GLN H CD  1 
ATOM 3489 O OE1 . GLN C 1 77  ? 207.706 233.483 176.035 1.00 479.73 ? 386 GLN H OE1 1 
ATOM 3490 N NE2 . GLN C 1 77  ? 207.893 232.293 177.930 1.00 479.73 ? 386 GLN H NE2 1 
ATOM 3491 N N   . ASN C 1 78  ? 203.477 230.041 173.181 1.00 443.37 ? 387 ASN H N   1 
ATOM 3492 C CA  . ASN C 1 78  ? 202.040 230.034 173.405 1.00 443.37 ? 387 ASN H CA  1 
ATOM 3493 C C   . ASN C 1 78  ? 201.449 228.695 172.992 1.00 443.37 ? 387 ASN H C   1 
ATOM 3494 O O   . ASN C 1 78  ? 200.487 228.646 172.217 1.00 443.37 ? 387 ASN H O   1 
ATOM 3495 C CB  . ASN C 1 78  ? 201.373 231.182 172.643 1.00 443.37 ? 387 ASN H CB  1 
ATOM 3496 C CG  . ASN C 1 78  ? 201.812 231.255 171.196 1.00 443.37 ? 387 ASN H CG  1 
ATOM 3497 O OD1 . ASN C 1 78  ? 202.577 230.415 170.723 1.00 443.37 ? 387 ASN H OD1 1 
ATOM 3498 N ND2 . ASN C 1 78  ? 201.330 232.266 170.482 1.00 443.37 ? 387 ASN H ND2 1 
ATOM 3499 N N   . ILE C 1 79  ? 202.043 227.604 173.466 1.00 374.73 ? 388 ILE H N   1 
ATOM 3500 C CA  . ILE C 1 79  ? 201.498 226.278 173.198 1.00 374.73 ? 388 ILE H CA  1 
ATOM 3501 C C   . ILE C 1 79  ? 200.388 226.007 174.208 1.00 374.73 ? 388 ILE H C   1 
ATOM 3502 O O   . ILE C 1 79  ? 200.634 225.921 175.414 1.00 374.73 ? 388 ILE H O   1 
ATOM 3503 C CB  . ILE C 1 79  ? 202.585 225.201 173.255 1.00 374.73 ? 388 ILE H CB  1 
ATOM 3504 C CG1 . ILE C 1 79  ? 203.812 225.654 172.463 1.00 374.73 ? 388 ILE H CG1 1 
ATOM 3505 C CG2 . ILE C 1 79  ? 202.054 223.890 172.704 1.00 374.73 ? 388 ILE H CG2 1 
ATOM 3506 C CD1 . ILE C 1 79  ? 203.593 225.678 170.965 1.00 374.73 ? 388 ILE H CD1 1 
ATOM 3507 N N   . ILE C 1 80  ? 199.163 225.879 173.710 1.00 330.50 ? 389 ILE H N   1 
ATOM 3508 C CA  . ILE C 1 80  ? 197.988 225.582 174.519 1.00 330.50 ? 389 ILE H CA  1 
ATOM 3509 C C   . ILE C 1 80  ? 197.296 224.346 173.960 1.00 330.50 ? 389 ILE H C   1 
ATOM 3510 O O   . ILE C 1 80  ? 196.591 223.631 174.681 1.00 330.50 ? 389 ILE H O   1 
ATOM 3511 C CB  . ILE C 1 80  ? 197.034 226.796 174.580 1.00 330.50 ? 389 ILE H CB  1 
ATOM 3512 C CG1 . ILE C 1 80  ? 197.670 227.976 175.331 1.00 330.50 ? 389 ILE H CG1 1 
ATOM 3513 C CG2 . ILE C 1 80  ? 195.670 226.434 175.141 1.00 330.50 ? 389 ILE H CG2 1 
ATOM 3514 C CD1 . ILE C 1 80  ? 198.437 228.933 174.479 1.00 330.50 ? 389 ILE H CD1 1 
ATOM 3515 N N   . GLU C 1 81  ? 197.559 224.036 172.696 1.00 353.55 ? 390 GLU H N   1 
ATOM 3516 C CA  . GLU C 1 81  ? 196.772 223.061 171.950 1.00 353.55 ? 390 GLU H CA  1 
ATOM 3517 C C   . GLU C 1 81  ? 197.590 221.802 171.682 1.00 353.55 ? 390 GLU H C   1 
ATOM 3518 O O   . GLU C 1 81  ? 197.594 221.252 170.579 1.00 353.55 ? 390 GLU H O   1 
ATOM 3519 C CB  . GLU C 1 81  ? 196.256 223.676 170.652 1.00 353.55 ? 390 GLU H CB  1 
ATOM 3520 C CG  . GLU C 1 81  ? 195.060 222.958 170.052 1.00 353.55 ? 390 GLU H CG  1 
ATOM 3521 C CD  . GLU C 1 81  ? 193.802 223.143 170.875 1.00 353.55 ? 390 GLU H CD  1 
ATOM 3522 O OE1 . GLU C 1 81  ? 193.693 224.174 171.573 1.00 353.55 ? 390 GLU H OE1 1 
ATOM 3523 O OE2 . GLU C 1 81  ? 192.926 222.256 170.830 1.00 353.55 ? 390 GLU H OE2 1 
ATOM 3524 N N   . ILE C 1 82  ? 198.315 221.336 172.696 1.00 298.39 ? 391 ILE H N   1 
ATOM 3525 C CA  . ILE C 1 82  ? 199.025 220.063 172.605 1.00 298.39 ? 391 ILE H CA  1 
ATOM 3526 C C   . ILE C 1 82  ? 197.988 218.940 172.595 1.00 298.39 ? 391 ILE H C   1 
ATOM 3527 O O   . ILE C 1 82  ? 197.071 218.912 173.418 1.00 298.39 ? 391 ILE H O   1 
ATOM 3528 C CB  . ILE C 1 82  ? 200.032 219.893 173.750 1.00 298.39 ? 391 ILE H CB  1 
ATOM 3529 C CG1 . ILE C 1 82  ? 200.842 218.610 173.570 1.00 298.39 ? 391 ILE H CG1 1 
ATOM 3530 C CG2 . ILE C 1 82  ? 199.346 219.907 175.096 1.00 298.39 ? 391 ILE H CG2 1 
ATOM 3531 C CD1 . ILE C 1 82  ? 202.032 218.515 174.496 1.00 298.39 ? 391 ILE H CD1 1 
ATOM 3532 N N   . ASN C 1 83  ? 198.112 218.028 171.630 1.00 315.90 ? 392 ASN H N   1 
ATOM 3533 C CA  . ASN C 1 83  ? 197.170 216.918 171.458 1.00 315.90 ? 392 ASN H CA  1 
ATOM 3534 C C   . ASN C 1 83  ? 197.917 215.807 170.721 1.00 315.90 ? 392 ASN H C   1 
ATOM 3535 O O   . ASN C 1 83  ? 198.090 215.865 169.500 1.00 315.90 ? 392 ASN H O   1 
ATOM 3536 C CB  . ASN C 1 83  ? 195.925 217.367 170.705 1.00 315.90 ? 392 ASN H CB  1 
ATOM 3537 C CG  . ASN C 1 83  ? 194.749 216.424 170.898 1.00 315.90 ? 392 ASN H CG  1 
ATOM 3538 O OD1 . ASN C 1 83  ? 194.922 215.211 171.009 1.00 315.90 ? 392 ASN H OD1 1 
ATOM 3539 N ND2 . ASN C 1 83  ? 193.548 216.984 170.973 1.00 315.90 ? 392 ASN H ND2 1 
ATOM 3540 N N   . ILE C 1 84  ? 198.366 214.803 171.472 1.00 300.61 ? 393 ILE H N   1 
ATOM 3541 C CA  . ILE C 1 84  ? 199.202 213.743 170.922 1.00 300.61 ? 393 ILE H CA  1 
ATOM 3542 C C   . ILE C 1 84  ? 198.525 212.395 171.158 1.00 300.61 ? 393 ILE H C   1 
ATOM 3543 O O   . ILE C 1 84  ? 199.189 211.389 171.426 1.00 300.61 ? 393 ILE H O   1 
ATOM 3544 C CB  . ILE C 1 84  ? 200.617 213.788 171.529 1.00 300.61 ? 393 ILE H CB  1 
ATOM 3545 C CG1 . ILE C 1 84  ? 201.158 215.214 171.520 1.00 300.61 ? 393 ILE H CG1 1 
ATOM 3546 C CG2 . ILE C 1 84  ? 201.593 212.980 170.691 1.00 300.61 ? 393 ILE H CG2 1 
ATOM 3547 C CD1 . ILE C 1 84  ? 202.194 215.471 172.586 1.00 300.61 ? 393 ILE H CD1 1 
ATOM 3548 N N   . SER C 1 85  ? 197.195 212.369 171.104 1.00 293.73 ? 394 SER H N   1 
ATOM 3549 C CA  . SER C 1 85  ? 196.463 211.135 171.364 1.00 293.73 ? 394 SER H CA  1 
ATOM 3550 C C   . SER C 1 85  ? 196.818 210.063 170.335 1.00 293.73 ? 394 SER H C   1 
ATOM 3551 O O   . SER C 1 85  ? 197.145 210.360 169.183 1.00 293.73 ? 394 SER H O   1 
ATOM 3552 C CB  . SER C 1 85  ? 194.958 211.396 171.354 1.00 293.73 ? 394 SER H CB  1 
ATOM 3553 O OG  . SER C 1 85  ? 194.505 211.747 170.063 1.00 293.73 ? 394 SER H OG  1 
ATOM 3554 N N   . ASP C 1 86  ? 196.756 208.802 170.772 1.00 267.21 ? 395 ASP H N   1 
ATOM 3555 C CA  . ASP C 1 86  ? 197.160 207.654 169.956 1.00 267.21 ? 395 ASP H CA  1 
ATOM 3556 C C   . ASP C 1 86  ? 198.620 207.759 169.523 1.00 267.21 ? 395 ASP H C   1 
ATOM 3557 O O   . ASP C 1 86  ? 198.995 207.338 168.427 1.00 267.21 ? 395 ASP H O   1 
ATOM 3558 C CB  . ASP C 1 86  ? 196.248 207.481 168.739 1.00 267.21 ? 395 ASP H CB  1 
ATOM 3559 C CG  . ASP C 1 86  ? 194.910 206.877 169.095 1.00 267.21 ? 395 ASP H CG  1 
ATOM 3560 O OD1 . ASP C 1 86  ? 194.867 205.650 169.315 1.00 267.21 ? 395 ASP H OD1 1 
ATOM 3561 O OD2 . ASP C 1 86  ? 193.906 207.618 169.157 1.00 267.21 ? 395 ASP H OD2 1 
ATOM 3562 N N   . CYS C 1 87  ? 199.454 208.315 170.398 1.00 301.67 ? 396 CYS H N   1 
ATOM 3563 C CA  . CYS C 1 87  ? 200.872 208.460 170.099 1.00 301.67 ? 396 CYS H CA  1 
ATOM 3564 C C   . CYS C 1 87  ? 201.586 207.116 170.172 1.00 301.67 ? 396 CYS H C   1 
ATOM 3565 O O   . CYS C 1 87  ? 201.294 206.284 171.036 1.00 301.67 ? 396 CYS H O   1 
ATOM 3566 C CB  . CYS C 1 87  ? 201.516 209.451 171.066 1.00 301.67 ? 396 CYS H CB  1 
ATOM 3567 S SG  . CYS C 1 87  ? 201.767 208.829 172.746 1.00 301.67 ? 396 CYS H SG  1 
ATOM 3568 N N   . ARG C 1 88  ? 202.525 206.905 169.248 1.00 345.52 ? 397 ARG H N   1 
ATOM 3569 C CA  . ARG C 1 88  ? 203.292 205.666 169.242 1.00 345.52 ? 397 ARG H CA  1 
ATOM 3570 C C   . ARG C 1 88  ? 204.759 205.866 168.880 1.00 345.52 ? 397 ARG H C   1 
ATOM 3571 O O   . ARG C 1 88  ? 205.442 204.881 168.571 1.00 345.52 ? 397 ARG H O   1 
ATOM 3572 C CB  . ARG C 1 88  ? 202.656 204.650 168.291 1.00 345.52 ? 397 ARG H CB  1 
ATOM 3573 C CG  . ARG C 1 88  ? 202.542 203.279 168.912 1.00 345.52 ? 397 ARG H CG  1 
ATOM 3574 C CD  . ARG C 1 88  ? 201.410 203.276 169.916 1.00 345.52 ? 397 ARG H CD  1 
ATOM 3575 N NE  . ARG C 1 88  ? 201.909 203.335 171.283 1.00 345.52 ? 397 ARG H NE  1 
ATOM 3576 C CZ  . ARG C 1 88  ? 201.397 202.653 172.298 1.00 345.52 ? 397 ARG H CZ  1 
ATOM 3577 N N   . SER C 1 89  ? 205.267 207.095 168.897 1.00 367.60 ? 398 SER H N   1 
ATOM 3578 C CA  . SER C 1 89  ? 206.653 207.355 168.532 1.00 367.60 ? 398 SER H CA  1 
ATOM 3579 C C   . SER C 1 89  ? 207.468 207.936 169.676 1.00 367.60 ? 398 SER H C   1 
ATOM 3580 O O   . SER C 1 89  ? 208.571 207.451 169.951 1.00 367.60 ? 398 SER H O   1 
ATOM 3581 C CB  . SER C 1 89  ? 206.708 208.296 167.319 1.00 367.60 ? 398 SER H CB  1 
ATOM 3582 O OG  . SER C 1 89  ? 208.041 208.481 166.874 1.00 367.60 ? 398 SER H OG  1 
ATOM 3583 N N   . MET C 1 90  ? 206.965 208.969 170.346 1.00 384.55 ? 399 MET H N   1 
ATOM 3584 C CA  . MET C 1 90  ? 207.756 209.634 171.368 1.00 384.55 ? 399 MET H CA  1 
ATOM 3585 C C   . MET C 1 90  ? 207.786 208.833 172.668 1.00 384.55 ? 399 MET H C   1 
ATOM 3586 O O   . MET C 1 90  ? 206.917 208.000 172.948 1.00 384.55 ? 399 MET H O   1 
ATOM 3587 C CB  . MET C 1 90  ? 207.232 211.045 171.622 1.00 384.55 ? 399 MET H CB  1 
ATOM 3588 C CG  . MET C 1 90  ? 207.915 212.081 170.752 1.00 384.55 ? 399 MET H CG  1 
ATOM 3589 S SD  . MET C 1 90  ? 207.376 213.773 171.037 1.00 384.55 ? 399 MET H SD  1 
ATOM 3590 C CE  . MET C 1 90  ? 208.654 214.641 170.138 1.00 384.55 ? 399 MET H CE  1 
ATOM 3591 N N   . SER C 1 91  ? 208.814 209.111 173.470 1.00 379.03 ? 400 SER H N   1 
ATOM 3592 C CA  . SER C 1 91  ? 209.096 208.386 174.702 1.00 379.03 ? 400 SER H CA  1 
ATOM 3593 C C   . SER C 1 91  ? 209.275 209.344 175.873 1.00 379.03 ? 400 SER H C   1 
ATOM 3594 O O   . SER C 1 91  ? 208.883 210.512 175.793 1.00 379.03 ? 400 SER H O   1 
ATOM 3595 C CB  . SER C 1 91  ? 210.341 207.511 174.540 1.00 379.03 ? 400 SER H CB  1 
ATOM 3596 O OG  . SER C 1 91  ? 211.414 208.250 173.982 1.00 379.03 ? 400 SER H OG  1 
ATOM 3597 N N   . ASP C 1 92  ? 209.850 208.840 176.968 1.00 366.65 ? 401 ASP H N   1 
ATOM 3598 C CA  . ASP C 1 92  ? 209.992 209.630 178.188 1.00 366.65 ? 401 ASP H CA  1 
ATOM 3599 C C   . ASP C 1 92  ? 210.741 210.936 177.938 1.00 366.65 ? 401 ASP H C   1 
ATOM 3600 O O   . ASP C 1 92  ? 210.231 212.022 178.236 1.00 366.65 ? 401 ASP H O   1 
ATOM 3601 C CB  . ASP C 1 92  ? 210.715 208.800 179.250 1.00 366.65 ? 401 ASP H CB  1 
ATOM 3602 C CG  . ASP C 1 92  ? 211.035 209.597 180.498 1.00 366.65 ? 401 ASP H CG  1 
ATOM 3603 O OD1 . ASP C 1 92  ? 210.094 209.950 181.238 1.00 366.65 ? 401 ASP H OD1 1 
ATOM 3604 O OD2 . ASP C 1 92  ? 212.231 209.874 180.736 1.00 366.65 ? 401 ASP H OD2 1 
ATOM 3605 N N   . ASN C 1 93  ? 211.947 210.854 177.376 1.00 372.30 ? 402 ASN H N   1 
ATOM 3606 C CA  . ASN C 1 93  ? 212.734 212.066 177.167 1.00 372.30 ? 402 ASN H CA  1 
ATOM 3607 C C   . ASN C 1 93  ? 212.166 212.900 176.027 1.00 372.30 ? 402 ASN H C   1 
ATOM 3608 O O   . ASN C 1 93  ? 212.236 214.136 176.053 1.00 372.30 ? 402 ASN H O   1 
ATOM 3609 C CB  . ASN C 1 93  ? 214.195 211.704 176.903 1.00 372.30 ? 402 ASN H CB  1 
ATOM 3610 C CG  . ASN C 1 93  ? 215.140 212.849 177.204 1.00 372.30 ? 402 ASN H CG  1 
ATOM 3611 O OD1 . ASN C 1 93  ? 214.716 213.932 177.602 1.00 372.30 ? 402 ASN H OD1 1 
ATOM 3612 N ND2 . ASN C 1 93  ? 216.433 212.609 177.026 1.00 372.30 ? 402 ASN H ND2 1 
ATOM 3613 N N   . GLY C 1 94  ? 211.591 212.240 175.020 1.00 382.84 ? 403 GLY H N   1 
ATOM 3614 C CA  . GLY C 1 94  ? 211.007 212.951 173.898 1.00 382.84 ? 403 GLY H CA  1 
ATOM 3615 C C   . GLY C 1 94  ? 209.804 213.791 174.261 1.00 382.84 ? 403 GLY H C   1 
ATOM 3616 O O   . GLY C 1 94  ? 209.455 214.710 173.513 1.00 382.84 ? 403 GLY H O   1 
ATOM 3617 N N   . VAL C 1 95  ? 209.158 213.496 175.386 1.00 364.70 ? 404 VAL H N   1 
ATOM 3618 C CA  . VAL C 1 95  ? 208.051 214.319 175.857 1.00 364.70 ? 404 VAL H CA  1 
ATOM 3619 C C   . VAL C 1 95  ? 208.567 215.222 176.968 1.00 364.70 ? 404 VAL H C   1 
ATOM 3620 O O   . VAL C 1 95  ? 208.027 216.308 177.201 1.00 364.70 ? 404 VAL H O   1 
ATOM 3621 C CB  . VAL C 1 95  ? 206.859 213.458 176.322 1.00 364.70 ? 404 VAL H CB  1 
ATOM 3622 C CG1 . VAL C 1 95  ? 207.208 212.676 177.576 1.00 364.70 ? 404 VAL H CG1 1 
ATOM 3623 C CG2 . VAL C 1 95  ? 205.624 214.323 176.545 1.00 364.70 ? 404 VAL H CG2 1 
ATOM 3624 N N   . CYS C 1 96  ? 209.636 214.793 177.644 1.00 363.47 ? 405 CYS H N   1 
ATOM 3625 C CA  . CYS C 1 96  ? 210.222 215.606 178.702 1.00 363.47 ? 405 CYS H CA  1 
ATOM 3626 C C   . CYS C 1 96  ? 210.884 216.862 178.159 1.00 363.47 ? 405 CYS H C   1 
ATOM 3627 O O   . CYS C 1 96  ? 210.917 217.882 178.857 1.00 363.47 ? 405 CYS H O   1 
ATOM 3628 C CB  . CYS C 1 96  ? 211.241 214.788 179.496 1.00 363.47 ? 405 CYS H CB  1 
ATOM 3629 S SG  . CYS C 1 96  ? 211.998 215.677 180.875 1.00 363.47 ? 405 CYS H SG  1 
ATOM 3630 N N   . VAL C 1 97  ? 211.419 216.807 176.939 1.00 354.84 ? 406 VAL H N   1 
ATOM 3631 C CA  . VAL C 1 97  ? 212.051 217.989 176.360 1.00 354.84 ? 406 VAL H CA  1 
ATOM 3632 C C   . VAL C 1 97  ? 211.031 219.109 176.186 1.00 354.84 ? 406 VAL H C   1 
ATOM 3633 O O   . VAL C 1 97  ? 211.310 220.275 176.495 1.00 354.84 ? 406 VAL H O   1 
ATOM 3634 C CB  . VAL C 1 97  ? 212.748 217.632 175.033 1.00 354.84 ? 406 VAL H CB  1 
ATOM 3635 C CG1 . VAL C 1 97  ? 214.027 216.861 175.307 1.00 354.84 ? 406 VAL H CG1 1 
ATOM 3636 C CG2 . VAL C 1 97  ? 211.824 216.815 174.147 1.00 354.84 ? 406 VAL H CG2 1 
ATOM 3637 N N   . LEU C 1 98  ? 209.835 218.779 175.693 1.00 360.64 ? 407 LEU H N   1 
ATOM 3638 C CA  . LEU C 1 98  ? 208.780 219.782 175.593 1.00 360.64 ? 407 LEU H CA  1 
ATOM 3639 C C   . LEU C 1 98  ? 208.207 220.120 176.961 1.00 360.64 ? 407 LEU H C   1 
ATOM 3640 O O   . LEU C 1 98  ? 207.909 221.287 177.241 1.00 360.64 ? 407 LEU H O   1 
ATOM 3641 C CB  . LEU C 1 98  ? 207.674 219.302 174.651 1.00 360.64 ? 407 LEU H CB  1 
ATOM 3642 C CG  . LEU C 1 98  ? 206.572 220.320 174.335 1.00 360.64 ? 407 LEU H CG  1 
ATOM 3643 C CD1 . LEU C 1 98  ? 206.172 220.266 172.870 1.00 360.64 ? 407 LEU H CD1 1 
ATOM 3644 C CD2 . LEU C 1 98  ? 205.351 220.092 175.221 1.00 360.64 ? 407 LEU H CD2 1 
ATOM 3645 N N   . ALA C 1 99  ? 208.056 219.118 177.825 1.00 368.87 ? 408 ALA H N   1 
ATOM 3646 C CA  . ALA C 1 99  ? 207.563 219.369 179.171 1.00 368.87 ? 408 ALA H CA  1 
ATOM 3647 C C   . ALA C 1 99  ? 208.558 220.166 179.999 1.00 368.87 ? 408 ALA H C   1 
ATOM 3648 O O   . ALA C 1 99  ? 208.210 220.626 181.092 1.00 368.87 ? 408 ALA H O   1 
ATOM 3649 C CB  . ALA C 1 99  ? 207.228 218.051 179.869 1.00 368.87 ? 408 ALA H CB  1 
ATOM 3650 N N   . PHE C 1 100 ? 209.787 220.332 179.506 1.00 358.11 ? 409 PHE H N   1 
ATOM 3651 C CA  . PHE C 1 100 ? 210.757 221.169 180.203 1.00 358.11 ? 409 PHE H CA  1 
ATOM 3652 C C   . PHE C 1 100 ? 210.248 222.597 180.344 1.00 358.11 ? 409 PHE H C   1 
ATOM 3653 O O   . PHE C 1 100 ? 210.431 223.228 181.392 1.00 358.11 ? 409 PHE H O   1 
ATOM 3654 C CB  . PHE C 1 100 ? 212.096 221.148 179.464 1.00 358.11 ? 409 PHE H CB  1 
ATOM 3655 C CG  . PHE C 1 100 ? 213.278 221.456 180.338 1.00 358.11 ? 409 PHE H CG  1 
ATOM 3656 C CD1 . PHE C 1 100 ? 213.487 220.762 181.517 1.00 358.11 ? 409 PHE H CD1 1 
ATOM 3657 C CD2 . PHE C 1 100 ? 214.176 222.445 179.982 1.00 358.11 ? 409 PHE H CD2 1 
ATOM 3658 C CE1 . PHE C 1 100 ? 214.572 221.048 182.323 1.00 358.11 ? 409 PHE H CE1 1 
ATOM 3659 C CE2 . PHE C 1 100 ? 215.263 222.735 180.784 1.00 358.11 ? 409 PHE H CE2 1 
ATOM 3660 C CZ  . PHE C 1 100 ? 215.461 222.036 181.957 1.00 358.11 ? 409 PHE H CZ  1 
ATOM 3661 N N   . LYS C 1 101 ? 209.600 223.124 179.305 1.00 347.60 ? 410 LYS H N   1 
ATOM 3662 C CA  . LYS C 1 101 ? 209.154 224.513 179.303 1.00 347.60 ? 410 LYS H CA  1 
ATOM 3663 C C   . LYS C 1 101 ? 207.709 224.656 179.772 1.00 347.60 ? 410 LYS H C   1 
ATOM 3664 O O   . LYS C 1 101 ? 207.447 225.334 180.769 1.00 347.60 ? 410 LYS H O   1 
ATOM 3665 C CB  . LYS C 1 101 ? 209.337 225.115 177.902 1.00 347.60 ? 410 LYS H CB  1 
ATOM 3666 C CG  . LYS C 1 101 ? 210.721 224.883 177.283 1.00 347.60 ? 410 LYS H CG  1 
ATOM 3667 C CD  . LYS C 1 101 ? 211.870 225.072 178.276 1.00 347.60 ? 410 LYS H CD  1 
ATOM 3668 C CE  . LYS C 1 101 ? 212.042 226.524 178.691 1.00 347.60 ? 410 LYS H CE  1 
ATOM 3669 N NZ  . LYS C 1 101 ? 213.042 226.654 179.787 1.00 347.60 ? 410 LYS H NZ  1 
ATOM 3670 N N   . CYS C 1 102 ? 206.764 224.002 179.082 1.00 351.46 ? 411 CYS H N   1 
ATOM 3671 C CA  . CYS C 1 102 ? 205.332 224.086 179.372 1.00 351.46 ? 411 CYS H CA  1 
ATOM 3672 C C   . CYS C 1 102 ? 204.869 225.524 179.575 1.00 351.46 ? 411 CYS H C   1 
ATOM 3673 O O   . CYS C 1 102 ? 204.471 225.890 180.688 1.00 351.46 ? 411 CYS H O   1 
ATOM 3674 C CB  . CYS C 1 102 ? 204.976 223.269 180.616 1.00 351.46 ? 411 CYS H CB  1 
ATOM 3675 S SG  . CYS C 1 102 ? 205.173 221.488 180.463 1.00 351.46 ? 411 CYS H SG  1 
ATOM 3676 N N   . PRO C 1 103 ? 204.906 226.368 178.551 1.00 338.63 ? 412 PRO H N   1 
ATOM 3677 C CA  . PRO C 1 103 ? 204.494 227.762 178.754 1.00 338.63 ? 412 PRO H CA  1 
ATOM 3678 C C   . PRO C 1 103 ? 202.982 227.929 178.741 1.00 338.63 ? 412 PRO H C   1 
ATOM 3679 O O   . PRO C 1 103 ? 202.367 227.920 177.671 1.00 338.63 ? 412 PRO H O   1 
ATOM 3680 C CB  . PRO C 1 103 ? 205.148 228.498 177.577 1.00 338.63 ? 412 PRO H CB  1 
ATOM 3681 C CG  . PRO C 1 103 ? 205.981 227.465 176.840 1.00 338.63 ? 412 PRO H CG  1 
ATOM 3682 C CD  . PRO C 1 103 ? 205.393 226.142 177.184 1.00 338.63 ? 412 PRO H CD  1 
ATOM 3683 N N   . GLY C 1 104 ? 202.379 228.097 179.917 1.00 274.57 ? 413 GLY H N   1 
ATOM 3684 C CA  . GLY C 1 104 ? 200.966 228.414 180.018 1.00 274.57 ? 413 GLY H CA  1 
ATOM 3685 C C   . GLY C 1 104 ? 200.034 227.417 179.361 1.00 274.57 ? 413 GLY H C   1 
ATOM 3686 O O   . GLY C 1 104 ? 199.112 227.807 178.640 1.00 274.57 ? 413 GLY H O   1 
ATOM 3687 N N   . LEU C 1 105 ? 200.266 226.130 179.596 1.00 251.52 ? 414 LEU H N   1 
ATOM 3688 C CA  . LEU C 1 105 ? 199.472 225.093 178.950 1.00 251.52 ? 414 LEU H CA  1 
ATOM 3689 C C   . LEU C 1 105 ? 198.047 225.075 179.490 1.00 251.52 ? 414 LEU H C   1 
ATOM 3690 O O   . LEU C 1 105 ? 197.813 225.308 180.677 1.00 251.52 ? 414 LEU H O   1 
ATOM 3691 C CB  . LEU C 1 105 ? 200.131 223.736 179.153 1.00 251.52 ? 414 LEU H CB  1 
ATOM 3692 C CG  . LEU C 1 105 ? 199.411 222.589 178.462 1.00 251.52 ? 414 LEU H CG  1 
ATOM 3693 C CD1 . LEU C 1 105 ? 199.423 222.830 176.975 1.00 251.52 ? 414 LEU H CD1 1 
ATOM 3694 C CD2 . LEU C 1 105 ? 200.095 221.283 178.806 1.00 251.52 ? 414 LEU H CD2 1 
ATOM 3695 N N   . LEU C 1 106 ? 197.085 224.807 178.607 1.00 221.20 ? 415 LEU H N   1 
ATOM 3696 C CA  . LEU C 1 106 ? 195.687 224.810 179.025 1.00 221.20 ? 415 LEU H CA  1 
ATOM 3697 C C   . LEU C 1 106 ? 194.940 223.540 178.633 1.00 221.20 ? 415 LEU H C   1 
ATOM 3698 O O   . LEU C 1 106 ? 194.076 223.075 179.382 1.00 221.20 ? 415 LEU H O   1 
ATOM 3699 C CB  . LEU C 1 106 ? 194.960 226.020 178.441 1.00 221.20 ? 415 LEU H CB  1 
ATOM 3700 C CG  . LEU C 1 106 ? 195.488 227.411 178.786 1.00 221.20 ? 415 LEU H CG  1 
ATOM 3701 C CD1 . LEU C 1 106 ? 194.659 228.480 178.089 1.00 221.20 ? 415 LEU H CD1 1 
ATOM 3702 C CD2 . LEU C 1 106 ? 195.481 227.619 180.285 1.00 221.20 ? 415 LEU H CD2 1 
ATOM 3703 N N   . ARG C 1 107 ? 195.250 222.966 177.473 1.00 230.63 ? 416 ARG H N   1 
ATOM 3704 C CA  . ARG C 1 107 ? 194.390 221.953 176.865 1.00 230.63 ? 416 ARG H CA  1 
ATOM 3705 C C   . ARG C 1 107 ? 195.172 220.678 176.576 1.00 230.63 ? 416 ARG H C   1 
ATOM 3706 O O   . ARG C 1 107 ? 195.124 220.125 175.476 1.00 230.63 ? 416 ARG H O   1 
ATOM 3707 C CB  . ARG C 1 107 ? 193.748 222.495 175.592 1.00 230.63 ? 416 ARG H CB  1 
ATOM 3708 C CG  . ARG C 1 107 ? 192.376 223.124 175.798 1.00 230.63 ? 416 ARG H CG  1 
ATOM 3709 C CD  . ARG C 1 107 ? 192.287 224.452 175.054 1.00 230.63 ? 416 ARG H CD  1 
ATOM 3710 N NE  . ARG C 1 107 ? 191.929 225.560 175.930 1.00 230.63 ? 416 ARG H NE  1 
ATOM 3711 C CZ  . ARG C 1 107 ? 191.188 226.597 175.563 1.00 230.63 ? 416 ARG H CZ  1 
ATOM 3712 N N   . TYR C 1 108 ? 195.915 220.196 177.568 1.00 215.84 ? 417 TYR H N   1 
ATOM 3713 C CA  . TYR C 1 108 ? 196.678 218.967 177.394 1.00 215.84 ? 417 TYR H CA  1 
ATOM 3714 C C   . TYR C 1 108 ? 195.745 217.775 177.242 1.00 215.84 ? 417 TYR H C   1 
ATOM 3715 O O   . TYR C 1 108 ? 194.892 217.524 178.096 1.00 215.84 ? 417 TYR H O   1 
ATOM 3716 C CB  . TYR C 1 108 ? 197.610 218.748 178.582 1.00 215.84 ? 417 TYR H CB  1 
ATOM 3717 C CG  . TYR C 1 108 ? 198.460 217.508 178.457 1.00 215.84 ? 417 TYR H CG  1 
ATOM 3718 C CD1 . TYR C 1 108 ? 199.599 217.503 177.665 1.00 215.84 ? 417 TYR H CD1 1 
ATOM 3719 C CD2 . TYR C 1 108 ? 198.118 216.337 179.119 1.00 215.84 ? 417 TYR H CD2 1 
ATOM 3720 C CE1 . TYR C 1 108 ? 200.379 216.373 177.542 1.00 215.84 ? 417 TYR H CE1 1 
ATOM 3721 C CE2 . TYR C 1 108 ? 198.892 215.199 179.000 1.00 215.84 ? 417 TYR H CE2 1 
ATOM 3722 C CZ  . TYR C 1 108 ? 200.022 215.223 178.211 1.00 215.84 ? 417 TYR H CZ  1 
ATOM 3723 N N   . THR C 1 109 ? 195.912 217.034 176.152 1.00 225.39 ? 418 THR H N   1 
ATOM 3724 C CA  . THR C 1 109 ? 195.091 215.860 175.875 1.00 225.39 ? 418 THR H CA  1 
ATOM 3725 C C   . THR C 1 109 ? 195.984 214.767 175.315 1.00 225.39 ? 418 THR H C   1 
ATOM 3726 O O   . THR C 1 109 ? 196.821 215.037 174.448 1.00 225.39 ? 418 THR H O   1 
ATOM 3727 C CB  . THR C 1 109 ? 193.972 216.186 174.883 1.00 225.39 ? 418 THR H CB  1 
ATOM 3728 O OG1 . THR C 1 109 ? 194.553 216.668 173.671 1.00 225.39 ? 418 THR H OG1 1 
ATOM 3729 C CG2 . THR C 1 109 ? 193.037 217.250 175.434 1.00 225.39 ? 418 THR H CG2 1 
ATOM 3730 N N   . ALA C 1 110 ? 195.811 213.538 175.804 1.00 213.02 ? 419 ALA H N   1 
ATOM 3731 C CA  . ALA C 1 110 ? 196.598 212.410 175.306 1.00 213.02 ? 419 ALA H CA  1 
ATOM 3732 C C   . ALA C 1 110 ? 195.797 211.130 175.539 1.00 213.02 ? 419 ALA H C   1 
ATOM 3733 O O   . ALA C 1 110 ? 195.823 210.572 176.639 1.00 213.02 ? 419 ALA H O   1 
ATOM 3734 C CB  . ALA C 1 110 ? 197.960 212.348 175.984 1.00 213.02 ? 419 ALA H CB  1 
ATOM 3735 N N   . TYR C 1 111 ? 195.114 210.661 174.498 1.00 231.28 ? 420 TYR H N   1 
ATOM 3736 C CA  . TYR C 1 111 ? 194.364 209.414 174.550 1.00 231.28 ? 420 TYR H CA  1 
ATOM 3737 C C   . TYR C 1 111 ? 195.231 208.266 174.047 1.00 231.28 ? 420 TYR H C   1 
ATOM 3738 O O   . TYR C 1 111 ? 195.972 208.415 173.070 1.00 231.28 ? 420 TYR H O   1 
ATOM 3739 C CB  . TYR C 1 111 ? 193.088 209.482 173.700 1.00 231.28 ? 420 TYR H CB  1 
ATOM 3740 C CG  . TYR C 1 111 ? 191.979 210.369 174.228 1.00 231.28 ? 420 TYR H CG  1 
ATOM 3741 C CD1 . TYR C 1 111 ? 191.239 210.003 175.344 1.00 231.28 ? 420 TYR H CD1 1 
ATOM 3742 C CD2 . TYR C 1 111 ? 191.635 211.547 173.573 1.00 231.28 ? 420 TYR H CD2 1 
ATOM 3743 C CE1 . TYR C 1 111 ? 190.218 210.803 175.822 1.00 231.28 ? 420 TYR H CE1 1 
ATOM 3744 C CE2 . TYR C 1 111 ? 190.609 212.351 174.040 1.00 231.28 ? 420 TYR H CE2 1 
ATOM 3745 C CZ  . TYR C 1 111 ? 189.905 211.974 175.164 1.00 231.28 ? 420 TYR H CZ  1 
ATOM 3746 N N   . ARG C 1 112 ? 195.135 207.124 174.724 1.00 245.03 ? 421 ARG H N   1 
ATOM 3747 C CA  . ARG C 1 112 ? 195.719 205.860 174.279 1.00 245.03 ? 421 ARG H CA  1 
ATOM 3748 C C   . ARG C 1 112 ? 197.220 205.945 174.029 1.00 245.03 ? 421 ARG H C   1 
ATOM 3749 O O   . ARG C 1 112 ? 197.718 205.373 173.053 1.00 245.03 ? 421 ARG H O   1 
ATOM 3750 C CB  . ARG C 1 112 ? 195.024 205.335 173.016 1.00 245.03 ? 421 ARG H CB  1 
ATOM 3751 C CG  . ARG C 1 112 ? 193.511 205.399 173.038 1.00 245.03 ? 421 ARG H CG  1 
ATOM 3752 C CD  . ARG C 1 112 ? 192.931 205.213 171.648 1.00 245.03 ? 421 ARG H CD  1 
ATOM 3753 N NE  . ARG C 1 112 ? 191.759 206.046 171.409 1.00 245.03 ? 421 ARG H NE  1 
ATOM 3754 C CZ  . ARG C 1 112 ? 190.737 206.155 172.246 1.00 245.03 ? 421 ARG H CZ  1 
ATOM 3755 N N   . CYS C 1 113 ? 197.967 206.649 174.877 1.00 285.86 ? 422 CYS H N   1 
ATOM 3756 C CA  . CYS C 1 113 ? 199.428 206.617 174.804 1.00 285.86 ? 422 CYS H CA  1 
ATOM 3757 C C   . CYS C 1 113 ? 199.933 205.574 175.795 1.00 285.86 ? 422 CYS H C   1 
ATOM 3758 O O   . CYS C 1 113 ? 200.418 205.884 176.882 1.00 285.86 ? 422 CYS H O   1 
ATOM 3759 C CB  . CYS C 1 113 ? 200.021 207.994 175.072 1.00 285.86 ? 422 CYS H CB  1 
ATOM 3760 S SG  . CYS C 1 113 ? 199.970 209.113 173.656 1.00 285.86 ? 422 CYS H SG  1 
ATOM 3761 N N   . LYS C 1 114 ? 199.827 204.306 175.387 1.00 296.03 ? 423 LYS H N   1 
ATOM 3762 C CA  . LYS C 1 114 ? 200.137 203.199 176.289 1.00 296.03 ? 423 LYS H CA  1 
ATOM 3763 C C   . LYS C 1 114 ? 201.569 203.279 176.799 1.00 296.03 ? 423 LYS H C   1 
ATOM 3764 O O   . LYS C 1 114 ? 201.825 203.080 177.992 1.00 296.03 ? 423 LYS H O   1 
ATOM 3765 C CB  . LYS C 1 114 ? 199.912 201.866 175.578 1.00 296.03 ? 423 LYS H CB  1 
ATOM 3766 C CG  . LYS C 1 114 ? 198.583 201.739 174.863 1.00 296.03 ? 423 LYS H CG  1 
ATOM 3767 C CD  . LYS C 1 114 ? 197.415 201.959 175.799 1.00 296.03 ? 423 LYS H CD  1 
ATOM 3768 C CE  . LYS C 1 114 ? 196.124 202.133 175.018 1.00 296.03 ? 423 LYS H CE  1 
ATOM 3769 N NZ  . LYS C 1 114 ? 195.018 201.336 175.614 1.00 296.03 ? 423 LYS H NZ  1 
ATOM 3770 N N   . GLN C 1 115 ? 202.518 203.570 175.909 1.00 324.21 ? 424 GLN H N   1 
ATOM 3771 C CA  . GLN C 1 115 ? 203.923 203.603 176.291 1.00 324.21 ? 424 GLN H CA  1 
ATOM 3772 C C   . GLN C 1 115 ? 204.260 204.787 177.186 1.00 324.21 ? 424 GLN H C   1 
ATOM 3773 O O   . GLN C 1 115 ? 205.345 204.808 177.777 1.00 324.21 ? 424 GLN H O   1 
ATOM 3774 C CB  . GLN C 1 115 ? 204.799 203.640 175.039 1.00 324.21 ? 424 GLN H CB  1 
ATOM 3775 C CG  . GLN C 1 115 ? 204.603 204.889 174.199 1.00 324.21 ? 424 GLN H CG  1 
ATOM 3776 C CD  . GLN C 1 115 ? 205.403 204.859 172.916 1.00 324.21 ? 424 GLN H CD  1 
ATOM 3777 O OE1 . GLN C 1 115 ? 206.128 203.902 172.647 1.00 324.21 ? 424 GLN H OE1 1 
ATOM 3778 N NE2 . GLN C 1 115 ? 205.285 205.914 172.120 1.00 324.21 ? 424 GLN H NE2 1 
ATOM 3779 N N   . LEU C 1 116 ? 203.365 205.766 177.298 1.00 328.51 ? 425 LEU H N   1 
ATOM 3780 C CA  . LEU C 1 116 ? 203.654 206.964 178.074 1.00 328.51 ? 425 LEU H CA  1 
ATOM 3781 C C   . LEU C 1 116 ? 203.896 206.620 179.537 1.00 328.51 ? 425 LEU H C   1 
ATOM 3782 O O   . LEU C 1 116 ? 203.210 205.781 180.124 1.00 328.51 ? 425 LEU H O   1 
ATOM 3783 C CB  . LEU C 1 116 ? 202.501 207.962 177.969 1.00 328.51 ? 425 LEU H CB  1 
ATOM 3784 C CG  . LEU C 1 116 ? 202.724 209.288 178.695 1.00 328.51 ? 425 LEU H CG  1 
ATOM 3785 C CD1 . LEU C 1 116 ? 203.906 210.020 178.088 1.00 328.51 ? 425 LEU H CD1 1 
ATOM 3786 C CD2 . LEU C 1 116 ? 201.473 210.147 178.657 1.00 328.51 ? 425 LEU H CD2 1 
ATOM 3787 N N   . SER C 1 117 ? 204.875 207.296 180.128 1.00 347.67 ? 426 SER H N   1 
ATOM 3788 C CA  . SER C 1 117 ? 205.247 207.094 181.520 1.00 347.67 ? 426 SER H CA  1 
ATOM 3789 C C   . SER C 1 117 ? 204.571 208.158 182.381 1.00 347.67 ? 426 SER H C   1 
ATOM 3790 O O   . SER C 1 117 ? 203.921 209.077 181.874 1.00 347.67 ? 426 SER H O   1 
ATOM 3791 C CB  . SER C 1 117 ? 206.770 207.113 181.675 1.00 347.67 ? 426 SER H CB  1 
ATOM 3792 O OG  . SER C 1 117 ? 207.261 208.441 181.725 1.00 347.67 ? 426 SER H OG  1 
ATOM 3793 N N   . ASP C 1 118 ? 204.709 208.017 183.701 1.00 307.32 ? 427 ASP H N   1 
ATOM 3794 C CA  . ASP C 1 118 ? 204.068 208.959 184.611 1.00 307.32 ? 427 ASP H CA  1 
ATOM 3795 C C   . ASP C 1 118 ? 205.003 210.101 184.988 1.00 307.32 ? 427 ASP H C   1 
ATOM 3796 O O   . ASP C 1 118 ? 204.553 211.141 185.489 1.00 307.32 ? 427 ASP H O   1 
ATOM 3797 C CB  . ASP C 1 118 ? 203.568 208.209 185.839 1.00 307.32 ? 427 ASP H CB  1 
ATOM 3798 C CG  . ASP C 1 118 ? 202.366 207.341 185.525 1.00 307.32 ? 427 ASP H CG  1 
ATOM 3799 O OD1 . ASP C 1 118 ? 201.576 207.721 184.636 1.00 307.32 ? 427 ASP H OD1 1 
ATOM 3800 O OD2 . ASP C 1 118 ? 202.229 206.261 186.132 1.00 307.32 ? 427 ASP H OD2 1 
ATOM 3801 N N   . THR C 1 119 ? 206.303 209.939 184.739 1.00 345.81 ? 428 THR H N   1 
ATOM 3802 C CA  . THR C 1 119 ? 207.211 211.070 184.864 1.00 345.81 ? 428 THR H CA  1 
ATOM 3803 C C   . THR C 1 119 ? 206.818 212.194 183.913 1.00 345.81 ? 428 THR H C   1 
ATOM 3804 O O   . THR C 1 119 ? 207.065 213.368 184.203 1.00 345.81 ? 428 THR H O   1 
ATOM 3805 C CB  . THR C 1 119 ? 208.652 210.628 184.601 1.00 345.81 ? 428 THR H CB  1 
ATOM 3806 O OG1 . THR C 1 119 ? 208.713 209.903 183.366 1.00 345.81 ? 428 THR H OG1 1 
ATOM 3807 C CG2 . THR C 1 119 ? 209.152 209.738 185.733 1.00 345.81 ? 428 THR H CG2 1 
ATOM 3808 N N   . SER C 1 120 ? 206.197 211.853 182.779 1.00 340.91 ? 429 SER H N   1 
ATOM 3809 C CA  . SER C 1 120 ? 205.712 212.879 181.860 1.00 340.91 ? 429 SER H CA  1 
ATOM 3810 C C   . SER C 1 120 ? 204.598 213.707 182.493 1.00 340.91 ? 429 SER H C   1 
ATOM 3811 O O   . SER C 1 120 ? 204.560 214.933 182.337 1.00 340.91 ? 429 SER H O   1 
ATOM 3812 C CB  . SER C 1 120 ? 205.234 212.237 180.558 1.00 340.91 ? 429 SER H CB  1 
ATOM 3813 O OG  . SER C 1 120 ? 204.678 213.207 179.687 1.00 340.91 ? 429 SER H OG  1 
ATOM 3814 N N   . ILE C 1 121 ? 203.669 213.056 183.202 1.00 325.82 ? 430 ILE H N   1 
ATOM 3815 C CA  . ILE C 1 121 ? 202.626 213.815 183.889 1.00 325.82 ? 430 ILE H CA  1 
ATOM 3816 C C   . ILE C 1 121 ? 203.238 214.636 185.015 1.00 325.82 ? 430 ILE H C   1 
ATOM 3817 O O   . ILE C 1 121 ? 202.829 215.783 185.252 1.00 325.82 ? 430 ILE H O   1 
ATOM 3818 C CB  . ILE C 1 121 ? 201.494 212.886 184.384 1.00 325.82 ? 430 ILE H CB  1 
ATOM 3819 C CG1 . ILE C 1 121 ? 200.170 213.644 184.444 1.00 325.82 ? 430 ILE H CG1 1 
ATOM 3820 C CG2 . ILE C 1 121 ? 201.774 212.317 185.757 1.00 325.82 ? 430 ILE H CG2 1 
ATOM 3821 C CD1 . ILE C 1 121 ? 199.707 214.173 183.115 1.00 325.82 ? 430 ILE H CD1 1 
ATOM 3822 N N   . ILE C 1 122 ? 204.260 214.093 185.685 1.00 337.94 ? 431 ILE H N   1 
ATOM 3823 C CA  . ILE C 1 122 ? 204.978 214.860 186.701 1.00 337.94 ? 431 ILE H CA  1 
ATOM 3824 C C   . ILE C 1 122 ? 205.542 216.140 186.098 1.00 337.94 ? 431 ILE H C   1 
ATOM 3825 O O   . ILE C 1 122 ? 205.365 217.238 186.637 1.00 337.94 ? 431 ILE H O   1 
ATOM 3826 C CB  . ILE C 1 122 ? 206.091 214.000 187.327 1.00 337.94 ? 431 ILE H CB  1 
ATOM 3827 C CG1 . ILE C 1 122 ? 205.499 212.840 188.133 1.00 337.94 ? 431 ILE H CG1 1 
ATOM 3828 C CG2 . ILE C 1 122 ? 207.034 214.857 188.162 1.00 337.94 ? 431 ILE H CG2 1 
ATOM 3829 C CD1 . ILE C 1 122 ? 206.531 211.818 188.572 1.00 337.94 ? 431 ILE H CD1 1 
ATOM 3830 N N   . ALA C 1 123 ? 206.213 216.015 184.951 1.00 345.91 ? 432 ALA H N   1 
ATOM 3831 C CA  . ALA C 1 123 ? 206.866 217.163 184.332 1.00 345.91 ? 432 ALA H CA  1 
ATOM 3832 C C   . ALA C 1 123 ? 205.860 218.167 183.786 1.00 345.91 ? 432 ALA H C   1 
ATOM 3833 O O   . ALA C 1 123 ? 206.076 219.378 183.901 1.00 345.91 ? 432 ALA H O   1 
ATOM 3834 C CB  . ALA C 1 123 ? 207.801 216.696 183.219 1.00 345.91 ? 432 ALA H CB  1 
ATOM 3835 N N   . VAL C 1 124 ? 204.761 217.696 183.193 1.00 333.27 ? 433 VAL H N   1 
ATOM 3836 C CA  . VAL C 1 124 ? 203.782 218.627 182.645 1.00 333.27 ? 433 VAL H CA  1 
ATOM 3837 C C   . VAL C 1 124 ? 203.009 219.330 183.752 1.00 333.27 ? 433 VAL H C   1 
ATOM 3838 O O   . VAL C 1 124 ? 202.505 220.438 183.540 1.00 333.27 ? 433 VAL H O   1 
ATOM 3839 C CB  . VAL C 1 124 ? 202.811 217.919 181.680 1.00 333.27 ? 433 VAL H CB  1 
ATOM 3840 C CG1 . VAL C 1 124 ? 201.877 216.985 182.431 1.00 333.27 ? 433 VAL H CG1 1 
ATOM 3841 C CG2 . VAL C 1 124 ? 202.028 218.930 180.847 1.00 333.27 ? 433 VAL H CG2 1 
ATOM 3842 N N   . ALA C 1 125 ? 202.925 218.737 184.943 1.00 311.49 ? 434 ALA H N   1 
ATOM 3843 C CA  . ALA C 1 125 ? 202.258 219.412 186.043 1.00 311.49 ? 434 ALA H CA  1 
ATOM 3844 C C   . ALA C 1 125 ? 203.185 220.291 186.867 1.00 311.49 ? 434 ALA H C   1 
ATOM 3845 O O   . ALA C 1 125 ? 202.714 221.263 187.469 1.00 311.49 ? 434 ALA H O   1 
ATOM 3846 C CB  . ALA C 1 125 ? 201.595 218.385 186.963 1.00 311.49 ? 434 ALA H CB  1 
ATOM 3847 N N   . SER C 1 126 ? 204.482 219.996 186.892 1.00 326.12 ? 435 SER H N   1 
ATOM 3848 C CA  . SER C 1 126 ? 205.420 220.699 187.756 1.00 326.12 ? 435 SER H CA  1 
ATOM 3849 C C   . SER C 1 126 ? 206.136 221.847 187.062 1.00 326.12 ? 435 SER H C   1 
ATOM 3850 O O   . SER C 1 126 ? 207.003 222.477 187.677 1.00 326.12 ? 435 SER H O   1 
ATOM 3851 C CB  . SER C 1 126 ? 206.454 219.717 188.319 1.00 326.12 ? 435 SER H CB  1 
ATOM 3852 O OG  . SER C 1 126 ? 207.324 219.252 187.302 1.00 326.12 ? 435 SER H OG  1 
ATOM 3853 N N   . HIS C 1 127 ? 205.805 222.136 185.802 1.00 338.94 ? 436 HIS H N   1 
ATOM 3854 C CA  . HIS C 1 127 ? 206.458 223.218 185.074 1.00 338.94 ? 436 HIS H CA  1 
ATOM 3855 C C   . HIS C 1 127 ? 205.457 224.256 184.579 1.00 338.94 ? 436 HIS H C   1 
ATOM 3856 O O   . HIS C 1 127 ? 205.852 225.230 183.930 1.00 338.94 ? 436 HIS H O   1 
ATOM 3857 C CB  . HIS C 1 127 ? 207.279 222.666 183.905 1.00 338.94 ? 436 HIS H CB  1 
ATOM 3858 C CG  . HIS C 1 127 ? 208.547 221.989 184.326 1.00 338.94 ? 436 HIS H CG  1 
ATOM 3859 N ND1 . HIS C 1 127 ? 209.327 221.256 183.457 1.00 338.94 ? 436 HIS H ND1 1 
ATOM 3860 C CD2 . HIS C 1 127 ? 209.162 221.919 185.531 1.00 338.94 ? 436 HIS H CD2 1 
ATOM 3861 C CE1 . HIS C 1 127 ? 210.371 220.772 184.106 1.00 338.94 ? 436 HIS H CE1 1 
ATOM 3862 N NE2 . HIS C 1 127 ? 210.294 221.159 185.365 1.00 338.94 ? 436 HIS H NE2 1 
ATOM 3863 N N   . CYS C 1 128 ? 204.175 224.071 184.870 1.00 304.41 ? 437 CYS H N   1 
ATOM 3864 C CA  . CYS C 1 128 ? 203.175 225.091 184.583 1.00 304.41 ? 437 CYS H CA  1 
ATOM 3865 C C   . CYS C 1 128 ? 202.023 224.960 185.570 1.00 304.41 ? 437 CYS H C   1 
ATOM 3866 O O   . CYS C 1 128 ? 201.260 223.987 185.518 1.00 304.41 ? 437 CYS H O   1 
ATOM 3867 C CB  . CYS C 1 128 ? 202.675 224.988 183.139 1.00 304.41 ? 437 CYS H CB  1 
ATOM 3868 S SG  . CYS C 1 128 ? 202.089 223.360 182.630 1.00 304.41 ? 437 CYS H SG  1 
ATOM 3869 N N   . PRO C 1 129 ? 201.867 225.912 186.486 1.00 280.86 ? 438 PRO H N   1 
ATOM 3870 C CA  . PRO C 1 129 ? 200.796 225.803 187.484 1.00 280.86 ? 438 PRO H CA  1 
ATOM 3871 C C   . PRO C 1 129 ? 199.424 226.100 186.902 1.00 280.86 ? 438 PRO H C   1 
ATOM 3872 O O   . PRO C 1 129 ? 198.403 225.901 187.566 1.00 280.86 ? 438 PRO H O   1 
ATOM 3873 C CB  . PRO C 1 129 ? 201.197 226.843 188.536 1.00 280.86 ? 438 PRO H CB  1 
ATOM 3874 C CG  . PRO C 1 129 ? 201.951 227.870 187.762 1.00 280.86 ? 438 PRO H CG  1 
ATOM 3875 C CD  . PRO C 1 129 ? 202.683 227.124 186.675 1.00 280.86 ? 438 PRO H CD  1 
ATOM 3876 N N   . LEU C 1 130 ? 199.385 226.569 185.659 1.00 245.85 ? 439 LEU H N   1 
ATOM 3877 C CA  . LEU C 1 130 ? 198.130 226.871 184.986 1.00 245.85 ? 439 LEU H CA  1 
ATOM 3878 C C   . LEU C 1 130 ? 197.832 225.759 183.997 1.00 245.85 ? 439 LEU H C   1 
ATOM 3879 O O   . LEU C 1 130 ? 198.689 225.405 183.181 1.00 245.85 ? 439 LEU H O   1 
ATOM 3880 C CB  . LEU C 1 130 ? 198.182 228.221 184.268 1.00 245.85 ? 439 LEU H CB  1 
ATOM 3881 C CG  . LEU C 1 130 ? 196.934 228.543 183.446 1.00 245.85 ? 439 LEU H CG  1 
ATOM 3882 C CD1 . LEU C 1 130 ? 195.712 228.607 184.340 1.00 245.85 ? 439 LEU H CD1 1 
ATOM 3883 C CD2 . LEU C 1 130 ? 197.108 229.847 182.683 1.00 245.85 ? 439 LEU H CD2 1 
ATOM 3884 N N   . LEU C 1 131 ? 196.628 225.203 184.090 1.00 209.05 ? 440 LEU H N   1 
ATOM 3885 C CA  . LEU C 1 131 ? 196.185 224.121 183.226 1.00 209.05 ? 440 LEU H CA  1 
ATOM 3886 C C   . LEU C 1 131 ? 194.666 224.095 183.257 1.00 209.05 ? 440 LEU H C   1 
ATOM 3887 O O   . LEU C 1 131 ? 194.047 224.393 184.279 1.00 209.05 ? 440 LEU H O   1 
ATOM 3888 C CB  . LEU C 1 131 ? 196.775 222.775 183.670 1.00 209.05 ? 440 LEU H CB  1 
ATOM 3889 C CG  . LEU C 1 131 ? 198.016 222.303 182.908 1.00 209.05 ? 440 LEU H CG  1 
ATOM 3890 C CD1 . LEU C 1 131 ? 198.602 221.045 183.524 1.00 209.05 ? 440 LEU H CD1 1 
ATOM 3891 C CD2 . LEU C 1 131 ? 197.655 222.067 181.465 1.00 209.05 ? 440 LEU H CD2 1 
ATOM 3892 N N   . GLN C 1 132 ? 194.062 223.750 182.126 1.00 156.41 ? 441 GLN H N   1 
ATOM 3893 C CA  . GLN C 1 132 ? 192.614 223.847 182.012 1.00 156.41 ? 441 GLN H CA  1 
ATOM 3894 C C   . GLN C 1 132 ? 191.937 222.604 181.452 1.00 156.41 ? 441 GLN H C   1 
ATOM 3895 O O   . GLN C 1 132 ? 190.781 222.347 181.813 1.00 156.41 ? 441 GLN H O   1 
ATOM 3896 C CB  . GLN C 1 132 ? 192.235 225.065 181.157 1.00 156.41 ? 441 GLN H CB  1 
ATOM 3897 C CG  . GLN C 1 132 ? 190.751 225.315 181.068 1.00 156.41 ? 441 GLN H CG  1 
ATOM 3898 C CD  . GLN C 1 132 ? 190.411 226.552 180.282 1.00 156.41 ? 441 GLN H CD  1 
ATOM 3899 O OE1 . GLN C 1 132 ? 189.244 226.919 180.148 1.00 156.41 ? 441 GLN H OE1 1 
ATOM 3900 N NE2 . GLN C 1 132 ? 191.431 227.201 179.738 1.00 156.41 ? 441 GLN H NE2 1 
ATOM 3901 N N   . LYS C 1 133 ? 192.608 221.813 180.615 1.00 170.33 ? 442 LYS H N   1 
ATOM 3902 C CA  . LYS C 1 133 ? 192.014 220.592 180.080 1.00 170.33 ? 442 LYS H CA  1 
ATOM 3903 C C   . LYS C 1 133 ? 193.068 219.495 180.113 1.00 170.33 ? 442 LYS H C   1 
ATOM 3904 O O   . LYS C 1 133 ? 194.169 219.683 179.590 1.00 170.33 ? 442 LYS H O   1 
ATOM 3905 C CB  . LYS C 1 133 ? 191.497 220.813 178.653 1.00 170.33 ? 442 LYS H CB  1 
ATOM 3906 C CG  . LYS C 1 133 ? 190.347 221.810 178.564 1.00 170.33 ? 442 LYS H CG  1 
ATOM 3907 C CD  . LYS C 1 133 ? 188.994 221.120 178.527 1.00 170.33 ? 442 LYS H CD  1 
ATOM 3908 C CE  . LYS C 1 133 ? 187.856 222.129 178.436 1.00 170.33 ? 442 LYS H CE  1 
ATOM 3909 N NZ  . LYS C 1 133 ? 186.719 221.640 177.611 1.00 170.33 ? 442 LYS H NZ  1 
ATOM 3910 N N   . VAL C 1 134 ? 192.731 218.359 180.729 1.00 162.19 ? 443 VAL H N   1 
ATOM 3911 C CA  . VAL C 1 134 ? 193.706 217.302 180.992 1.00 162.19 ? 443 VAL H CA  1 
ATOM 3912 C C   . VAL C 1 134 ? 193.255 215.974 180.379 1.00 162.19 ? 443 VAL H C   1 
ATOM 3913 O O   . VAL C 1 134 ? 193.516 214.898 180.928 1.00 162.19 ? 443 VAL H O   1 
ATOM 3914 C CB  . VAL C 1 134 ? 193.976 217.184 182.508 1.00 162.19 ? 443 VAL H CB  1 
ATOM 3915 C CG1 . VAL C 1 134 ? 192.810 216.537 183.239 1.00 162.19 ? 443 VAL H CG1 1 
ATOM 3916 C CG2 . VAL C 1 134 ? 195.301 216.460 182.785 1.00 162.19 ? 443 VAL H CG2 1 
ATOM 3917 N N   . HIS C 1 135 ? 192.624 216.026 179.206 1.00 171.41 ? 444 HIS H N   1 
ATOM 3918 C CA  . HIS C 1 135 ? 191.966 214.834 178.682 1.00 171.41 ? 444 HIS H CA  1 
ATOM 3919 C C   . HIS C 1 135 ? 192.970 213.750 178.307 1.00 171.41 ? 444 HIS H C   1 
ATOM 3920 O O   . HIS C 1 135 ? 193.336 213.614 177.135 1.00 171.41 ? 444 HIS H O   1 
ATOM 3921 C CB  . HIS C 1 135 ? 191.125 215.171 177.444 1.00 171.41 ? 444 HIS H CB  1 
ATOM 3922 C CG  . HIS C 1 135 ? 189.808 215.819 177.745 1.00 171.41 ? 444 HIS H CG  1 
ATOM 3923 N ND1 . HIS C 1 135 ? 188.952 216.249 176.753 1.00 171.41 ? 444 HIS H ND1 1 
ATOM 3924 C CD2 . HIS C 1 135 ? 189.195 216.102 178.918 1.00 171.41 ? 444 HIS H CD2 1 
ATOM 3925 C CE1 . HIS C 1 135 ? 187.870 216.771 177.303 1.00 171.41 ? 444 HIS H CE1 1 
ATOM 3926 N NE2 . HIS C 1 135 ? 187.992 216.693 178.616 1.00 171.41 ? 444 HIS H NE2 1 
ATOM 3927 N N   . VAL C 1 136 ? 193.413 212.967 179.294 1.00 164.18 ? 445 VAL H N   1 
ATOM 3928 C CA  . VAL C 1 136 ? 194.186 211.763 179.023 1.00 164.18 ? 445 VAL H CA  1 
ATOM 3929 C C   . VAL C 1 136 ? 193.210 210.635 178.716 1.00 164.18 ? 445 VAL H C   1 
ATOM 3930 O O   . VAL C 1 136 ? 192.001 210.749 178.935 1.00 164.18 ? 445 VAL H O   1 
ATOM 3931 C CB  . VAL C 1 136 ? 195.121 211.366 180.184 1.00 164.18 ? 445 VAL H CB  1 
ATOM 3932 C CG1 . VAL C 1 136 ? 196.026 212.524 180.591 1.00 164.18 ? 445 VAL H CG1 1 
ATOM 3933 C CG2 . VAL C 1 136 ? 194.321 210.841 181.342 1.00 164.18 ? 445 VAL H CG2 1 
ATOM 3934 N N   . GLY C 1 137 ? 193.739 209.528 178.206 1.00 189.71 ? 446 GLY H N   1 
ATOM 3935 C CA  . GLY C 1 137 ? 192.875 208.429 177.828 1.00 189.71 ? 446 GLY H CA  1 
ATOM 3936 C C   . GLY C 1 137 ? 193.317 207.043 178.243 1.00 189.71 ? 446 GLY H C   1 
ATOM 3937 O O   . GLY C 1 137 ? 193.590 206.780 179.419 1.00 189.71 ? 446 GLY H O   1 
ATOM 3938 N N   . ASN C 1 138 ? 193.382 206.142 177.261 1.00 214.83 ? 447 ASN H N   1 
ATOM 3939 C CA  . ASN C 1 138 ? 193.610 204.717 177.464 1.00 214.83 ? 447 ASN H CA  1 
ATOM 3940 C C   . ASN C 1 138 ? 195.027 204.393 177.898 1.00 214.83 ? 447 ASN H C   1 
ATOM 3941 O O   . ASN C 1 138 ? 195.386 203.210 177.920 1.00 214.83 ? 447 ASN H O   1 
ATOM 3942 C CB  . ASN C 1 138 ? 193.271 203.945 176.184 1.00 214.83 ? 447 ASN H CB  1 
ATOM 3943 C CG  . ASN C 1 138 ? 191.773 203.777 175.968 1.00 214.83 ? 447 ASN H CG  1 
ATOM 3944 O OD1 . ASN C 1 138 ? 191.044 203.392 176.876 1.00 214.83 ? 447 ASN H OD1 1 
ATOM 3945 N ND2 . ASN C 1 138 ? 191.309 204.073 174.761 1.00 214.83 ? 447 ASN H ND2 1 
ATOM 3946 N N   . GLN C 1 139 ? 195.839 205.391 178.240 1.00 244.66 ? 448 GLN H N   1 
ATOM 3947 C CA  . GLN C 1 139 ? 197.183 205.109 178.720 1.00 244.66 ? 448 GLN H CA  1 
ATOM 3948 C C   . GLN C 1 139 ? 197.103 204.281 179.990 1.00 244.66 ? 448 GLN H C   1 
ATOM 3949 O O   . GLN C 1 139 ? 196.472 204.688 180.969 1.00 244.66 ? 448 GLN H O   1 
ATOM 3950 C CB  . GLN C 1 139 ? 197.947 206.402 178.986 1.00 244.66 ? 448 GLN H CB  1 
ATOM 3951 C CG  . GLN C 1 139 ? 199.291 206.164 179.655 1.00 244.66 ? 448 GLN H CG  1 
ATOM 3952 C CD  . GLN C 1 139 ? 199.235 206.352 181.146 1.00 244.66 ? 448 GLN H CD  1 
ATOM 3953 O OE1 . GLN C 1 139 ? 198.214 206.761 181.683 1.00 244.66 ? 448 GLN H OE1 1 
ATOM 3954 N NE2 . GLN C 1 139 ? 200.331 206.039 181.828 1.00 244.66 ? 448 GLN H NE2 1 
ATOM 3955 N N   . ASP C 1 140 ? 197.736 203.117 179.967 1.00 247.07 ? 449 ASP H N   1 
ATOM 3956 C CA  . ASP C 1 140 ? 197.703 202.211 181.103 1.00 247.07 ? 449 ASP H CA  1 
ATOM 3957 C C   . ASP C 1 140 ? 198.846 202.574 182.046 1.00 247.07 ? 449 ASP H C   1 
ATOM 3958 O O   . ASP C 1 140 ? 199.644 203.472 181.767 1.00 247.07 ? 449 ASP H O   1 
ATOM 3959 C CB  . ASP C 1 140 ? 197.769 200.771 180.614 1.00 247.07 ? 449 ASP H CB  1 
ATOM 3960 C CG  . ASP C 1 140 ? 196.494 200.344 179.927 1.00 247.07 ? 449 ASP H CG  1 
ATOM 3961 O OD1 . ASP C 1 140 ? 195.426 200.898 180.264 1.00 247.07 ? 449 ASP H OD1 1 
ATOM 3962 O OD2 . ASP C 1 140 ? 196.559 199.470 179.040 1.00 247.07 ? 449 ASP H OD2 1 
ATOM 3963 N N   . LYS C 1 141 ? 198.933 201.870 183.179 1.00 252.67 ? 450 LYS H N   1 
ATOM 3964 C CA  . LYS C 1 141 ? 199.960 202.102 184.193 1.00 252.67 ? 450 LYS H CA  1 
ATOM 3965 C C   . LYS C 1 141 ? 200.147 203.587 184.508 1.00 252.67 ? 450 LYS H C   1 
ATOM 3966 O O   . LYS C 1 141 ? 201.269 204.091 184.599 1.00 252.67 ? 450 LYS H O   1 
ATOM 3967 C CB  . LYS C 1 141 ? 201.248 201.355 183.794 1.00 252.67 ? 450 LYS H CB  1 
ATOM 3968 C CG  . LYS C 1 141 ? 201.992 201.739 182.507 1.00 252.67 ? 450 LYS H CG  1 
ATOM 3969 C CD  . LYS C 1 141 ? 203.057 202.798 182.639 1.00 252.67 ? 450 LYS H CD  1 
ATOM 3970 C CE  . LYS C 1 141 ? 203.757 202.966 181.304 1.00 252.67 ? 450 LYS H CE  1 
ATOM 3971 N NZ  . LYS C 1 141 ? 204.809 204.005 181.341 1.00 252.67 ? 450 LYS H NZ  1 
ATOM 3972 N N   . LEU C 1 142 ? 199.022 204.284 184.707 1.00 225.24 ? 451 LEU H N   1 
ATOM 3973 C CA  . LEU C 1 142 ? 198.987 205.661 185.202 1.00 225.24 ? 451 LEU H CA  1 
ATOM 3974 C C   . LEU C 1 142 ? 199.021 205.616 186.723 1.00 225.24 ? 451 LEU H C   1 
ATOM 3975 O O   . LEU C 1 142 ? 197.986 205.432 187.365 1.00 225.24 ? 451 LEU H O   1 
ATOM 3976 C CB  . LEU C 1 142 ? 197.733 206.380 184.718 1.00 225.24 ? 451 LEU H CB  1 
ATOM 3977 C CG  . LEU C 1 142 ? 197.668 207.904 184.852 1.00 225.24 ? 451 LEU H CG  1 
ATOM 3978 C CD1 . LEU C 1 142 ? 196.739 208.465 183.799 1.00 225.24 ? 451 LEU H CD1 1 
ATOM 3979 C CD2 . LEU C 1 142 ? 197.202 208.335 186.235 1.00 225.24 ? 451 LEU H CD2 1 
ATOM 3980 N N   . THR C 1 143 ? 200.200 205.817 187.303 1.00 237.02 ? 452 THR H N   1 
ATOM 3981 C CA  . THR C 1 143 ? 200.325 205.686 188.745 1.00 237.02 ? 452 THR H CA  1 
ATOM 3982 C C   . THR C 1 143 ? 199.492 206.753 189.455 1.00 237.02 ? 452 THR H C   1 
ATOM 3983 O O   . THR C 1 143 ? 199.130 207.787 188.889 1.00 237.02 ? 452 THR H O   1 
ATOM 3984 C CB  . THR C 1 143 ? 201.789 205.790 189.179 1.00 237.02 ? 452 THR H CB  1 
ATOM 3985 O OG1 . THR C 1 143 ? 201.922 205.308 190.519 1.00 237.02 ? 452 THR H OG1 1 
ATOM 3986 C CG2 . THR C 1 143 ? 202.266 207.234 189.129 1.00 237.02 ? 452 THR H CG2 1 
ATOM 3987 N N   . ASP C 1 144 ? 199.168 206.473 190.714 1.00 197.22 ? 453 ASP H N   1 
ATOM 3988 C CA  . ASP C 1 144 ? 198.463 207.448 191.529 1.00 197.22 ? 453 ASP H CA  1 
ATOM 3989 C C   . ASP C 1 144 ? 199.421 208.424 192.197 1.00 197.22 ? 453 ASP H C   1 
ATOM 3990 O O   . ASP C 1 144 ? 198.966 209.350 192.876 1.00 197.22 ? 453 ASP H O   1 
ATOM 3991 C CB  . ASP C 1 144 ? 197.593 206.720 192.557 1.00 197.22 ? 453 ASP H CB  1 
ATOM 3992 C CG  . ASP C 1 144 ? 196.317 207.468 192.872 1.00 197.22 ? 453 ASP H CG  1 
ATOM 3993 O OD1 . ASP C 1 144 ? 196.217 208.655 192.506 1.00 197.22 ? 453 ASP H OD1 1 
ATOM 3994 O OD2 . ASP C 1 144 ? 195.386 206.845 193.422 1.00 197.22 ? 453 ASP H OD2 1 
ATOM 3995 N N   . GLU C 1 145 ? 200.731 208.223 192.025 1.00 235.59 ? 454 GLU H N   1 
ATOM 3996 C CA  . GLU C 1 145 ? 201.707 209.237 192.409 1.00 235.59 ? 454 GLU H CA  1 
ATOM 3997 C C   . GLU C 1 145 ? 201.648 210.438 191.475 1.00 235.59 ? 454 GLU H C   1 
ATOM 3998 O O   . GLU C 1 145 ? 201.772 211.586 191.915 1.00 235.59 ? 454 GLU H O   1 
ATOM 3999 C CB  . GLU C 1 145 ? 203.120 208.646 192.398 1.00 235.59 ? 454 GLU H CB  1 
ATOM 4000 C CG  . GLU C 1 145 ? 203.492 207.810 193.608 1.00 235.59 ? 454 GLU H CG  1 
ATOM 4001 C CD  . GLU C 1 145 ? 203.025 206.376 193.480 1.00 235.59 ? 454 GLU H CD  1 
ATOM 4002 O OE1 . GLU C 1 145 ? 202.472 206.029 192.419 1.00 235.59 ? 454 GLU H OE1 1 
ATOM 4003 O OE2 . GLU C 1 145 ? 203.224 205.590 194.429 1.00 235.59 ? 454 GLU H OE2 1 
ATOM 4004 N N   . GLY C 1 146 ? 201.482 210.191 190.174 1.00 215.99 ? 455 GLY H N   1 
ATOM 4005 C CA  . GLY C 1 146 ? 201.498 211.283 189.215 1.00 215.99 ? 455 GLY H CA  1 
ATOM 4006 C C   . GLY C 1 146 ? 200.373 212.273 189.440 1.00 215.99 ? 455 GLY H C   1 
ATOM 4007 O O   . GLY C 1 146 ? 200.591 213.488 189.407 1.00 215.99 ? 455 GLY H O   1 
ATOM 4008 N N   . LEU C 1 147 ? 199.163 211.767 189.691 1.00 201.22 ? 456 LEU H N   1 
ATOM 4009 C CA  . LEU C 1 147 ? 198.051 212.643 190.037 1.00 201.22 ? 456 LEU H CA  1 
ATOM 4010 C C   . LEU C 1 147 ? 198.337 213.429 191.307 1.00 201.22 ? 456 LEU H C   1 
ATOM 4011 O O   . LEU C 1 147 ? 197.862 214.560 191.453 1.00 201.22 ? 456 LEU H O   1 
ATOM 4012 C CB  . LEU C 1 147 ? 196.765 211.829 190.205 1.00 201.22 ? 456 LEU H CB  1 
ATOM 4013 C CG  . LEU C 1 147 ? 195.427 212.576 190.195 1.00 201.22 ? 456 LEU H CG  1 
ATOM 4014 C CD1 . LEU C 1 147 ? 194.313 211.680 189.704 1.00 201.22 ? 456 LEU H CD1 1 
ATOM 4015 C CD2 . LEU C 1 147 ? 195.081 213.105 191.569 1.00 201.22 ? 456 LEU H CD2 1 
ATOM 4016 N N   . LYS C 1 148 ? 199.106 212.854 192.231 1.00 240.20 ? 457 LYS H N   1 
ATOM 4017 C CA  . LYS C 1 148 ? 199.395 213.546 193.480 1.00 240.20 ? 457 LYS H CA  1 
ATOM 4018 C C   . LYS C 1 148 ? 200.091 214.875 193.211 1.00 240.20 ? 457 LYS H C   1 
ATOM 4019 O O   . LYS C 1 148 ? 199.606 215.941 193.614 1.00 240.20 ? 457 LYS H O   1 
ATOM 4020 C CB  . LYS C 1 148 ? 200.257 212.650 194.372 1.00 240.20 ? 457 LYS H CB  1 
ATOM 4021 C CG  . LYS C 1 148 ? 199.468 211.599 195.134 1.00 240.20 ? 457 LYS H CG  1 
ATOM 4022 C CD  . LYS C 1 148 ? 200.123 211.229 196.451 1.00 240.20 ? 457 LYS H CD  1 
ATOM 4023 C CE  . LYS C 1 148 ? 199.434 210.024 197.066 1.00 240.20 ? 457 LYS H CE  1 
ATOM 4024 N NZ  . LYS C 1 148 ? 199.132 208.988 196.038 1.00 240.20 ? 457 LYS H NZ  1 
ATOM 4025 N N   . GLN C 1 149 ? 201.201 214.834 192.469 1.00 266.64 ? 458 GLN H N   1 
ATOM 4026 C CA  . GLN C 1 149 ? 201.916 216.067 192.159 1.00 266.64 ? 458 GLN H CA  1 
ATOM 4027 C C   . GLN C 1 149 ? 201.159 216.902 191.138 1.00 266.64 ? 458 GLN H C   1 
ATOM 4028 O O   . GLN C 1 149 ? 201.274 218.132 191.132 1.00 266.64 ? 458 GLN H O   1 
ATOM 4029 C CB  . GLN C 1 149 ? 203.330 215.753 191.676 1.00 266.64 ? 458 GLN H CB  1 
ATOM 4030 C CG  . GLN C 1 149 ? 204.216 215.145 192.756 1.00 266.64 ? 458 GLN H CG  1 
ATOM 4031 C CD  . GLN C 1 149 ? 205.614 214.839 192.265 1.00 266.64 ? 458 GLN H CD  1 
ATOM 4032 O OE1 . GLN C 1 149 ? 205.921 215.023 191.088 1.00 266.64 ? 458 GLN H OE1 1 
ATOM 4033 N NE2 . GLN C 1 149 ? 206.471 214.375 193.165 1.00 266.64 ? 458 GLN H NE2 1 
ATOM 4034 N N   . LEU C 1 150 ? 200.367 216.261 190.275 1.00 247.93 ? 459 LEU H N   1 
ATOM 4035 C CA  . LEU C 1 150 ? 199.539 217.028 189.354 1.00 247.93 ? 459 LEU H CA  1 
ATOM 4036 C C   . LEU C 1 150 ? 198.599 217.956 190.107 1.00 247.93 ? 459 LEU H C   1 
ATOM 4037 O O   . LEU C 1 150 ? 198.559 219.163 189.843 1.00 247.93 ? 459 LEU H O   1 
ATOM 4038 C CB  . LEU C 1 150 ? 198.751 216.083 188.446 1.00 247.93 ? 459 LEU H CB  1 
ATOM 4039 C CG  . LEU C 1 150 ? 197.954 216.696 187.291 1.00 247.93 ? 459 LEU H CG  1 
ATOM 4040 C CD1 . LEU C 1 150 ? 197.806 215.684 186.173 1.00 247.93 ? 459 LEU H CD1 1 
ATOM 4041 C CD2 . LEU C 1 150 ? 196.575 217.162 187.744 1.00 247.93 ? 459 LEU H CD2 1 
ATOM 4042 N N   . GLY C 1 151 ? 197.843 217.412 191.061 1.00 263.03 ? 460 GLY H N   1 
ATOM 4043 C CA  . GLY C 1 151 ? 196.925 218.219 191.839 1.00 263.03 ? 460 GLY H CA  1 
ATOM 4044 C C   . GLY C 1 151 ? 197.590 219.121 192.849 1.00 263.03 ? 460 GLY H C   1 
ATOM 4045 O O   . GLY C 1 151 ? 197.014 220.150 193.217 1.00 263.03 ? 460 GLY H O   1 
ATOM 4046 N N   . SER C 1 152 ? 198.788 218.760 193.307 1.00 284.51 ? 461 SER H N   1 
ATOM 4047 C CA  . SER C 1 152 ? 199.494 219.645 194.223 1.00 284.51 ? 461 SER H CA  1 
ATOM 4048 C C   . SER C 1 152 ? 200.023 220.881 193.508 1.00 284.51 ? 461 SER H C   1 
ATOM 4049 O O   . SER C 1 152 ? 199.872 222.000 194.011 1.00 284.51 ? 461 SER H O   1 
ATOM 4050 C CB  . SER C 1 152 ? 200.637 218.889 194.901 1.00 284.51 ? 461 SER H CB  1 
ATOM 4051 O OG  . SER C 1 152 ? 201.793 218.861 194.080 1.00 284.51 ? 461 SER H OG  1 
ATOM 4052 N N   . LYS C 1 153 ? 200.615 220.709 192.324 1.00 284.73 ? 462 LYS H N   1 
ATOM 4053 C CA  . LYS C 1 153 ? 201.329 221.813 191.688 1.00 284.73 ? 462 LYS H CA  1 
ATOM 4054 C C   . LYS C 1 153 ? 200.370 222.786 191.008 1.00 284.73 ? 462 LYS H C   1 
ATOM 4055 O O   . LYS C 1 153 ? 200.308 223.966 191.370 1.00 284.73 ? 462 LYS H O   1 
ATOM 4056 C CB  . LYS C 1 153 ? 202.347 221.265 190.683 1.00 284.73 ? 462 LYS H CB  1 
ATOM 4057 C CG  . LYS C 1 153 ? 203.388 220.317 191.273 1.00 284.73 ? 462 LYS H CG  1 
ATOM 4058 C CD  . LYS C 1 153 ? 204.019 220.851 192.544 1.00 284.73 ? 462 LYS H CD  1 
ATOM 4059 C CE  . LYS C 1 153 ? 205.119 221.847 192.229 1.00 284.73 ? 462 LYS H CE  1 
ATOM 4060 N NZ  . LYS C 1 153 ? 206.105 221.953 193.342 1.00 284.73 ? 462 LYS H NZ  1 
ATOM 4061 N N   . CYS C 1 154 ? 199.607 222.308 190.026 1.00 270.25 ? 463 CYS H N   1 
ATOM 4062 C CA  . CYS C 1 154 ? 198.776 223.181 189.193 1.00 270.25 ? 463 CYS H CA  1 
ATOM 4063 C C   . CYS C 1 154 ? 197.350 223.193 189.734 1.00 270.25 ? 463 CYS H C   1 
ATOM 4064 O O   . CYS C 1 154 ? 196.512 222.364 189.378 1.00 270.25 ? 463 CYS H O   1 
ATOM 4065 C CB  . CYS C 1 154 ? 198.847 222.735 187.736 1.00 270.25 ? 463 CYS H CB  1 
ATOM 4066 S SG  . CYS C 1 154 ? 198.207 221.076 187.372 1.00 270.25 ? 463 CYS H SG  1 
ATOM 4067 N N   . ARG C 1 155 ? 197.065 224.159 190.602 1.00 254.99 ? 464 ARG H N   1 
ATOM 4068 C CA  . ARG C 1 155 ? 195.761 224.245 191.265 1.00 254.99 ? 464 ARG H CA  1 
ATOM 4069 C C   . ARG C 1 155 ? 194.799 225.202 190.557 1.00 254.99 ? 464 ARG H C   1 
ATOM 4070 O O   . ARG C 1 155 ? 194.264 226.133 191.158 1.00 254.99 ? 464 ARG H O   1 
ATOM 4071 C CB  . ARG C 1 155 ? 195.957 224.632 192.726 1.00 254.99 ? 464 ARG H CB  1 
ATOM 4072 C CG  . ARG C 1 155 ? 197.273 225.339 193.014 1.00 254.99 ? 464 ARG H CG  1 
ATOM 4073 C CD  . ARG C 1 155 ? 197.236 226.046 194.359 1.00 254.99 ? 464 ARG H CD  1 
ATOM 4074 N NE  . ARG C 1 155 ? 197.333 225.107 195.470 1.00 254.99 ? 464 ARG H NE  1 
ATOM 4075 C CZ  . ARG C 1 155 ? 197.088 225.414 196.736 1.00 254.99 ? 464 ARG H CZ  1 
ATOM 4076 N N   . GLU C 1 156 ? 194.568 224.977 189.265 1.00 189.21 ? 465 GLU H N   1 
ATOM 4077 C CA  . GLU C 1 156 ? 193.598 225.761 188.503 1.00 189.21 ? 465 GLU H CA  1 
ATOM 4078 C C   . GLU C 1 156 ? 192.730 224.931 187.568 1.00 189.21 ? 465 GLU H C   1 
ATOM 4079 O O   . GLU C 1 156 ? 191.736 225.452 187.055 1.00 189.21 ? 465 GLU H O   1 
ATOM 4080 C CB  . GLU C 1 156 ? 194.326 226.855 187.703 1.00 189.21 ? 465 GLU H CB  1 
ATOM 4081 C CG  . GLU C 1 156 ? 193.426 227.805 186.929 1.00 189.21 ? 465 GLU H CG  1 
ATOM 4082 C CD  . GLU C 1 156 ? 192.484 228.589 187.817 1.00 189.21 ? 465 GLU H CD  1 
ATOM 4083 O OE1 . GLU C 1 156 ? 192.811 228.816 189.001 1.00 189.21 ? 465 GLU H OE1 1 
ATOM 4084 O OE2 . GLU C 1 156 ? 191.405 228.975 187.324 1.00 189.21 ? 465 GLU H OE2 1 
ATOM 4085 N N   . LEU C 1 157 ? 193.028 223.648 187.389 1.00 157.34 ? 466 LEU H N   1 
ATOM 4086 C CA  . LEU C 1 157 ? 192.406 222.836 186.353 1.00 157.34 ? 466 LEU H CA  1 
ATOM 4087 C C   . LEU C 1 157 ? 190.885 222.840 186.473 1.00 157.34 ? 466 LEU H C   1 
ATOM 4088 O O   . LEU C 1 157 ? 190.333 222.902 187.574 1.00 157.34 ? 466 LEU H O   1 
ATOM 4089 C CB  . LEU C 1 157 ? 192.935 221.416 186.462 1.00 157.34 ? 466 LEU H CB  1 
ATOM 4090 C CG  . LEU C 1 157 ? 192.434 220.460 185.403 1.00 157.34 ? 466 LEU H CG  1 
ATOM 4091 C CD1 . LEU C 1 157 ? 192.914 220.971 184.076 1.00 157.34 ? 466 LEU H CD1 1 
ATOM 4092 C CD2 . LEU C 1 157 ? 192.987 219.092 185.681 1.00 157.34 ? 466 LEU H CD2 1 
ATOM 4093 N N   . LYS C 1 158 ? 190.202 222.790 185.328 1.00 115.26 ? 467 LYS H N   1 
ATOM 4094 C CA  . LYS C 1 158 ? 188.750 222.866 185.319 1.00 115.26 ? 467 LYS H CA  1 
ATOM 4095 C C   . LYS C 1 158 ? 188.070 221.814 184.449 1.00 115.26 ? 467 LYS H C   1 
ATOM 4096 O O   . LYS C 1 158 ? 186.856 221.901 184.244 1.00 115.26 ? 467 LYS H O   1 
ATOM 4097 C CB  . LYS C 1 158 ? 188.311 224.275 184.894 1.00 115.26 ? 467 LYS H CB  1 
ATOM 4098 C CG  . LYS C 1 158 ? 188.321 224.549 183.415 1.00 115.26 ? 467 LYS H CG  1 
ATOM 4099 C CD  . LYS C 1 158 ? 187.880 225.979 183.165 1.00 115.26 ? 467 LYS H CD  1 
ATOM 4100 C CE  . LYS C 1 158 ? 186.380 226.101 183.046 1.00 115.26 ? 467 LYS H CE  1 
ATOM 4101 N NZ  . LYS C 1 158 ? 185.897 225.679 181.711 1.00 115.26 ? 467 LYS H NZ  1 
ATOM 4102 N N   . ASP C 1 159 ? 188.802 220.815 183.956 1.00 114.68 ? 468 ASP H N   1 
ATOM 4103 C CA  . ASP C 1 159 ? 188.218 219.780 183.102 1.00 114.68 ? 468 ASP H CA  1 
ATOM 4104 C C   . ASP C 1 159 ? 189.133 218.563 183.098 1.00 114.68 ? 468 ASP H C   1 
ATOM 4105 O O   . ASP C 1 159 ? 190.318 218.691 182.777 1.00 114.68 ? 468 ASP H O   1 
ATOM 4106 C CB  . ASP C 1 159 ? 188.040 220.320 181.697 1.00 114.68 ? 468 ASP H CB  1 
ATOM 4107 C CG  . ASP C 1 159 ? 186.945 219.623 180.944 1.00 114.68 ? 468 ASP H CG  1 
ATOM 4108 O OD1 . ASP C 1 159 ? 186.976 218.379 180.870 1.00 114.68 ? 468 ASP H OD1 1 
ATOM 4109 O OD2 . ASP C 1 159 ? 186.062 220.320 180.404 1.00 114.68 ? 468 ASP H OD2 1 
ATOM 4110 N N   . ILE C 1 160 ? 188.594 217.380 183.419 1.00 93.85  ? 469 ILE H N   1 
ATOM 4111 C CA  . ILE C 1 160 ? 189.404 216.172 183.536 1.00 93.85  ? 469 ILE H CA  1 
ATOM 4112 C C   . ILE C 1 160 ? 188.795 215.032 182.727 1.00 93.85  ? 469 ILE H C   1 
ATOM 4113 O O   . ILE C 1 160 ? 187.594 214.993 182.453 1.00 93.85  ? 469 ILE H O   1 
ATOM 4114 C CB  . ILE C 1 160 ? 189.583 215.709 184.993 1.00 93.85  ? 469 ILE H CB  1 
ATOM 4115 C CG1 . ILE C 1 160 ? 188.228 215.427 185.626 1.00 93.85  ? 469 ILE H CG1 1 
ATOM 4116 C CG2 . ILE C 1 160 ? 190.326 216.742 185.786 1.00 93.85  ? 469 ILE H CG2 1 
ATOM 4117 C CD1 . ILE C 1 160 ? 188.308 214.752 186.957 1.00 93.85  ? 469 ILE H CD1 1 
ATOM 4118 N N   . HIS C 1 161 ? 189.656 214.078 182.377 1.00 117.17 ? 470 HIS H N   1 
ATOM 4119 C CA  . HIS C 1 161 ? 189.244 212.838 181.724 1.00 117.17 ? 470 HIS H CA  1 
ATOM 4120 C C   . HIS C 1 161 ? 190.209 211.745 182.152 1.00 117.17 ? 470 HIS H C   1 
ATOM 4121 O O   . HIS C 1 161 ? 191.238 211.540 181.505 1.00 117.17 ? 470 HIS H O   1 
ATOM 4122 C CB  . HIS C 1 161 ? 189.240 213.002 180.208 1.00 117.17 ? 470 HIS H CB  1 
ATOM 4123 C CG  . HIS C 1 161 ? 188.662 211.837 179.469 1.00 117.17 ? 470 HIS H CG  1 
ATOM 4124 N ND1 . HIS C 1 161 ? 189.306 210.622 179.375 1.00 117.17 ? 470 HIS H ND1 1 
ATOM 4125 C CD2 . HIS C 1 161 ? 187.508 211.704 178.775 1.00 117.17 ? 470 HIS H CD2 1 
ATOM 4126 C CE1 . HIS C 1 161 ? 188.569 209.790 178.662 1.00 117.17 ? 470 HIS H CE1 1 
ATOM 4127 N NE2 . HIS C 1 161 ? 187.472 210.421 178.287 1.00 117.17 ? 470 HIS H NE2 1 
ATOM 4128 N N   . PHE C 1 162 ? 189.868 211.040 183.229 1.00 118.94 ? 471 PHE H N   1 
ATOM 4129 C CA  . PHE C 1 162 ? 190.646 209.927 183.764 1.00 118.94 ? 471 PHE H CA  1 
ATOM 4130 C C   . PHE C 1 162 ? 189.851 208.638 183.690 1.00 118.94 ? 471 PHE H C   1 
ATOM 4131 O O   . PHE C 1 162 ? 189.724 207.906 184.675 1.00 118.94 ? 471 PHE H O   1 
ATOM 4132 C CB  . PHE C 1 162 ? 191.093 210.174 185.207 1.00 118.94 ? 471 PHE H CB  1 
ATOM 4133 C CG  . PHE C 1 162 ? 192.429 210.844 185.337 1.00 118.94 ? 471 PHE H CG  1 
ATOM 4134 C CD1 . PHE C 1 162 ? 193.497 210.427 184.572 1.00 118.94 ? 471 PHE H CD1 1 
ATOM 4135 C CD2 . PHE C 1 162 ? 192.630 211.854 186.256 1.00 118.94 ? 471 PHE H CD2 1 
ATOM 4136 C CE1 . PHE C 1 162 ? 194.729 211.024 184.699 1.00 118.94 ? 471 PHE H CE1 1 
ATOM 4137 C CE2 . PHE C 1 162 ? 193.863 212.454 186.380 1.00 118.94 ? 471 PHE H CE2 1 
ATOM 4138 C CZ  . PHE C 1 162 ? 194.914 212.036 185.602 1.00 118.94 ? 471 PHE H CZ  1 
ATOM 4139 N N   . GLY C 1 163 ? 189.299 208.337 182.525 1.00 123.34 ? 472 GLY H N   1 
ATOM 4140 C CA  . GLY C 1 163 ? 188.705 207.037 182.335 1.00 123.34 ? 472 GLY H CA  1 
ATOM 4141 C C   . GLY C 1 163 ? 189.764 205.960 182.197 1.00 123.34 ? 472 GLY H C   1 
ATOM 4142 O O   . GLY C 1 163 ? 190.947 206.237 182.003 1.00 123.34 ? 472 GLY H O   1 
ATOM 4143 N N   . GLN C 1 164 ? 189.312 204.710 182.313 1.00 131.05 ? 473 GLN H N   1 
ATOM 4144 C CA  . GLN C 1 164 ? 190.099 203.513 181.999 1.00 131.05 ? 473 GLN H CA  1 
ATOM 4145 C C   . GLN C 1 164 ? 191.505 203.543 182.601 1.00 131.05 ? 473 GLN H C   1 
ATOM 4146 O O   . GLN C 1 164 ? 192.480 203.125 181.973 1.00 131.05 ? 473 GLN H O   1 
ATOM 4147 C CB  . GLN C 1 164 ? 190.160 203.276 180.485 1.00 131.05 ? 473 GLN H CB  1 
ATOM 4148 C CG  . GLN C 1 164 ? 190.904 204.326 179.674 1.00 131.05 ? 473 GLN H CG  1 
ATOM 4149 C CD  . GLN C 1 164 ? 189.988 205.382 179.096 1.00 131.05 ? 473 GLN H CD  1 
ATOM 4150 O OE1 . GLN C 1 164 ? 188.831 205.486 179.474 1.00 131.05 ? 473 GLN H OE1 1 
ATOM 4151 N NE2 . GLN C 1 164 ? 190.502 206.164 178.163 1.00 131.05 ? 473 GLN H NE2 1 
ATOM 4152 N N   . CYS C 1 165 ? 191.620 204.019 183.836 1.00 150.36 ? 474 CYS H N   1 
ATOM 4153 C CA  . CYS C 1 165 ? 192.867 203.929 184.592 1.00 150.36 ? 474 CYS H CA  1 
ATOM 4154 C C   . CYS C 1 165 ? 192.523 203.304 185.939 1.00 150.36 ? 474 CYS H C   1 
ATOM 4155 O O   . CYS C 1 165 ? 192.272 204.010 186.918 1.00 150.36 ? 474 CYS H O   1 
ATOM 4156 C CB  . CYS C 1 165 ? 193.522 205.292 184.743 1.00 150.36 ? 474 CYS H CB  1 
ATOM 4157 S SG  . CYS C 1 165 ? 193.946 206.066 183.170 1.00 150.36 ? 474 CYS H SG  1 
ATOM 4158 N N   . TYR C 1 166 ? 192.518 201.974 185.989 1.00 140.66 ? 475 TYR H N   1 
ATOM 4159 C CA  . TYR C 1 166 ? 192.019 201.246 187.157 1.00 140.66 ? 475 TYR H CA  1 
ATOM 4160 C C   . TYR C 1 166 ? 193.092 201.064 188.224 1.00 140.66 ? 475 TYR H C   1 
ATOM 4161 O O   . TYR C 1 166 ? 193.303 199.979 188.762 1.00 140.66 ? 475 TYR H O   1 
ATOM 4162 C CB  . TYR C 1 166 ? 191.455 199.906 186.706 1.00 140.66 ? 475 TYR H CB  1 
ATOM 4163 C CG  . TYR C 1 166 ? 191.255 199.844 185.210 1.00 140.66 ? 475 TYR H CG  1 
ATOM 4164 C CD1 . TYR C 1 166 ? 190.100 200.349 184.627 1.00 140.66 ? 475 TYR H CD1 1 
ATOM 4165 C CD2 . TYR C 1 166 ? 192.226 199.300 184.375 1.00 140.66 ? 475 TYR H CD2 1 
ATOM 4166 C CE1 . TYR C 1 166 ? 189.910 200.305 183.261 1.00 140.66 ? 475 TYR H CE1 1 
ATOM 4167 C CE2 . TYR C 1 166 ? 192.044 199.253 183.003 1.00 140.66 ? 475 TYR H CE2 1 
ATOM 4168 C CZ  . TYR C 1 166 ? 190.884 199.757 182.453 1.00 140.66 ? 475 TYR H CZ  1 
ATOM 4169 N N   . LYS C 1 167 ? 193.775 202.161 188.527 1.00 151.76 ? 476 LYS H N   1 
ATOM 4170 C CA  . LYS C 1 167 ? 194.687 202.249 189.659 1.00 151.76 ? 476 LYS H CA  1 
ATOM 4171 C C   . LYS C 1 167 ? 194.652 203.638 190.279 1.00 151.76 ? 476 LYS H C   1 
ATOM 4172 O O   . LYS C 1 167 ? 195.590 204.018 190.988 1.00 151.76 ? 476 LYS H O   1 
ATOM 4173 C CB  . LYS C 1 167 ? 196.089 201.869 189.216 1.00 151.76 ? 476 LYS H CB  1 
ATOM 4174 C CG  . LYS C 1 167 ? 196.667 202.823 188.221 1.00 151.76 ? 476 LYS H CG  1 
ATOM 4175 C CD  . LYS C 1 167 ? 198.056 202.389 187.863 1.00 151.76 ? 476 LYS H CD  1 
ATOM 4176 C CE  . LYS C 1 167 ? 197.944 201.136 187.010 1.00 151.76 ? 476 LYS H CE  1 
ATOM 4177 N NZ  . LYS C 1 167 ? 197.294 201.406 185.700 1.00 151.76 ? 476 LYS H NZ  1 
ATOM 4178 N N   . ILE C 1 168 ? 193.599 204.407 190.007 1.00 147.79 ? 477 ILE H N   1 
ATOM 4179 C CA  . ILE C 1 168 ? 193.418 205.742 190.563 1.00 147.79 ? 477 ILE H CA  1 
ATOM 4180 C C   . ILE C 1 168 ? 192.118 205.691 191.351 1.00 147.79 ? 477 ILE H C   1 
ATOM 4181 O O   . ILE C 1 168 ? 191.355 206.659 191.404 1.00 147.79 ? 477 ILE H O   1 
ATOM 4182 C CB  . ILE C 1 168 ? 193.378 206.809 189.458 1.00 147.79 ? 477 ILE H CB  1 
ATOM 4183 C CG1 . ILE C 1 168 ? 194.571 206.604 188.540 1.00 147.79 ? 477 ILE H CG1 1 
ATOM 4184 C CG2 . ILE C 1 168 ? 193.464 208.221 190.053 1.00 147.79 ? 477 ILE H CG2 1 
ATOM 4185 C CD1 . ILE C 1 168 ? 195.873 206.679 189.248 1.00 147.79 ? 477 ILE H CD1 1 
ATOM 4186 N N   . SER C 1 169 ? 191.843 204.526 191.920 1.00 129.20 ? 478 SER H N   1 
ATOM 4187 C CA  . SER C 1 169 ? 190.544 204.184 192.480 1.00 129.20 ? 478 SER H CA  1 
ATOM 4188 C C   . SER C 1 169 ? 190.005 205.164 193.520 1.00 129.20 ? 478 SER H C   1 
ATOM 4189 O O   . SER C 1 169 ? 188.874 205.646 193.386 1.00 129.20 ? 478 SER H O   1 
ATOM 4190 C CB  . SER C 1 169 ? 190.645 202.782 193.066 1.00 129.20 ? 478 SER H CB  1 
ATOM 4191 O OG  . SER C 1 169 ? 191.254 201.899 192.143 1.00 129.20 ? 478 SER H OG  1 
ATOM 4192 N N   . ASP C 1 170 ? 190.790 205.472 194.559 1.00 146.83 ? 479 ASP H N   1 
ATOM 4193 C CA  . ASP C 1 170 ? 190.325 206.412 195.586 1.00 146.83 ? 479 ASP H CA  1 
ATOM 4194 C C   . ASP C 1 170 ? 191.243 207.605 195.799 1.00 146.83 ? 479 ASP H C   1 
ATOM 4195 O O   . ASP C 1 170 ? 190.749 208.704 196.073 1.00 146.83 ? 479 ASP H O   1 
ATOM 4196 C CB  . ASP C 1 170 ? 190.119 205.735 196.939 1.00 146.83 ? 479 ASP H CB  1 
ATOM 4197 C CG  . ASP C 1 170 ? 189.296 206.587 197.887 1.00 146.83 ? 479 ASP H CG  1 
ATOM 4198 O OD1 . ASP C 1 170 ? 189.822 207.569 198.438 1.00 146.83 ? 479 ASP H OD1 1 
ATOM 4199 O OD2 . ASP C 1 170 ? 188.093 206.316 198.078 1.00 146.83 ? 479 ASP H OD2 1 
ATOM 4200 N N   . GLU C 1 171 ? 192.564 207.416 195.723 1.00 181.34 ? 480 GLU H N   1 
ATOM 4201 C CA  . GLU C 1 171 ? 193.472 208.478 196.152 1.00 181.34 ? 480 GLU H CA  1 
ATOM 4202 C C   . GLU C 1 171 ? 193.329 209.729 195.301 1.00 181.34 ? 480 GLU H C   1 
ATOM 4203 O O   . GLU C 1 171 ? 193.282 210.836 195.846 1.00 181.34 ? 480 GLU H O   1 
ATOM 4204 C CB  . GLU C 1 171 ? 194.928 208.011 196.121 1.00 181.34 ? 480 GLU H CB  1 
ATOM 4205 C CG  . GLU C 1 171 ? 195.277 206.940 197.125 1.00 181.34 ? 480 GLU H CG  1 
ATOM 4206 C CD  . GLU C 1 171 ? 196.731 206.510 197.036 1.00 181.34 ? 480 GLU H CD  1 
ATOM 4207 O OE1 . GLU C 1 171 ? 197.426 206.971 196.107 1.00 181.34 ? 480 GLU H OE1 1 
ATOM 4208 O OE2 . GLU C 1 171 ? 197.161 205.667 197.859 1.00 181.34 ? 480 GLU H OE2 1 
ATOM 4209 N N   . GLY C 1 172 ? 193.237 209.582 193.979 1.00 167.79 ? 481 GLY H N   1 
ATOM 4210 C CA  . GLY C 1 172 ? 193.183 210.755 193.123 1.00 167.79 ? 481 GLY H CA  1 
ATOM 4211 C C   . GLY C 1 172 ? 192.006 211.645 193.452 1.00 167.79 ? 481 GLY H C   1 
ATOM 4212 O O   . GLY C 1 172 ? 192.104 212.875 193.389 1.00 167.79 ? 481 GLY H O   1 
ATOM 4213 N N   . MET C 1 173 ? 190.891 211.033 193.846 1.00 157.52 ? 482 MET H N   1 
ATOM 4214 C CA  . MET C 1 173 ? 189.749 211.819 194.274 1.00 157.52 ? 482 MET H CA  1 
ATOM 4215 C C   . MET C 1 173 ? 190.149 212.761 195.392 1.00 157.52 ? 482 MET H C   1 
ATOM 4216 O O   . MET C 1 173 ? 190.030 213.977 195.254 1.00 157.52 ? 482 MET H O   1 
ATOM 4217 C CB  . MET C 1 173 ? 188.622 210.904 194.741 1.00 157.52 ? 482 MET H CB  1 
ATOM 4218 C CG  . MET C 1 173 ? 187.425 211.605 195.404 1.00 157.52 ? 482 MET H CG  1 
ATOM 4219 S SD  . MET C 1 173 ? 187.615 212.488 196.965 1.00 157.52 ? 482 MET H SD  1 
ATOM 4220 C CE  . MET C 1 173 ? 187.221 211.208 198.117 1.00 157.52 ? 482 MET H CE  1 
ATOM 4221 N N   . ILE C 1 174 ? 190.643 212.221 196.504 1.00 171.54 ? 483 ILE H N   1 
ATOM 4222 C CA  . ILE C 1 174 ? 190.889 213.087 197.646 1.00 171.54 ? 483 ILE H CA  1 
ATOM 4223 C C   . ILE C 1 174 ? 192.007 214.072 197.316 1.00 171.54 ? 483 ILE H C   1 
ATOM 4224 O O   . ILE C 1 174 ? 191.966 215.240 197.739 1.00 171.54 ? 483 ILE H O   1 
ATOM 4225 C CB  . ILE C 1 174 ? 191.172 212.249 198.909 1.00 171.54 ? 483 ILE H CB  1 
ATOM 4226 C CG1 . ILE C 1 174 ? 191.083 213.133 200.148 1.00 171.54 ? 483 ILE H CG1 1 
ATOM 4227 C CG2 . ILE C 1 174 ? 192.524 211.551 198.835 1.00 171.54 ? 483 ILE H CG2 1 
ATOM 4228 C CD1 . ILE C 1 174 ? 189.677 213.623 200.391 1.00 171.54 ? 483 ILE H CD1 1 
ATOM 4229 N N   . VAL C 1 175 ? 192.985 213.638 196.511 1.00 183.38 ? 484 VAL H N   1 
ATOM 4230 C CA  . VAL C 1 175 ? 194.102 214.497 196.132 1.00 183.38 ? 484 VAL H CA  1 
ATOM 4231 C C   . VAL C 1 175 ? 193.599 215.744 195.419 1.00 183.38 ? 484 VAL H C   1 
ATOM 4232 O O   . VAL C 1 175 ? 193.780 216.865 195.907 1.00 183.38 ? 484 VAL H O   1 
ATOM 4233 C CB  . VAL C 1 175 ? 195.112 213.720 195.270 1.00 183.38 ? 484 VAL H CB  1 
ATOM 4234 C CG1 . VAL C 1 175 ? 196.112 214.672 194.643 1.00 183.38 ? 484 VAL H CG1 1 
ATOM 4235 C CG2 . VAL C 1 175 ? 195.828 212.681 196.109 1.00 183.38 ? 484 VAL H CG2 1 
ATOM 4236 N N   . ILE C 1 176 ? 192.956 215.586 194.260 1.00 166.95 ? 485 ILE H N   1 
ATOM 4237 C CA  . ILE C 1 176 ? 192.242 216.755 193.770 1.00 166.95 ? 485 ILE H CA  1 
ATOM 4238 C C   . ILE C 1 176 ? 190.819 216.663 194.292 1.00 166.95 ? 485 ILE H C   1 
ATOM 4239 O O   . ILE C 1 176 ? 189.861 216.590 193.520 1.00 166.95 ? 485 ILE H O   1 
ATOM 4240 C CB  . ILE C 1 176 ? 192.274 216.843 192.234 1.00 166.95 ? 485 ILE H CB  1 
ATOM 4241 C CG1 . ILE C 1 176 ? 191.889 215.506 191.597 1.00 166.95 ? 485 ILE H CG1 1 
ATOM 4242 C CG2 . ILE C 1 176 ? 193.640 217.239 191.755 1.00 166.95 ? 485 ILE H CG2 1 
ATOM 4243 C CD1 . ILE C 1 176 ? 191.731 215.576 190.106 1.00 166.95 ? 485 ILE H CD1 1 
ATOM 4244 N N   . ALA C 1 177 ? 190.682 216.698 195.612 1.00 154.79 ? 486 ALA H N   1 
ATOM 4245 C CA  . ALA C 1 177 ? 189.437 217.005 196.297 1.00 154.79 ? 486 ALA H CA  1 
ATOM 4246 C C   . ALA C 1 177 ? 189.621 217.949 197.459 1.00 154.79 ? 486 ALA H C   1 
ATOM 4247 O O   . ALA C 1 177 ? 188.693 218.697 197.767 1.00 154.79 ? 486 ALA H O   1 
ATOM 4248 C CB  . ALA C 1 177 ? 188.781 215.729 196.824 1.00 154.79 ? 486 ALA H CB  1 
ATOM 4249 N N   . LYS C 1 178 ? 190.783 217.962 198.107 1.00 146.83 ? 487 LYS H N   1 
ATOM 4250 C CA  . LYS C 1 178 ? 191.034 218.982 199.117 1.00 146.83 ? 487 LYS H CA  1 
ATOM 4251 C C   . LYS C 1 178 ? 191.340 220.317 198.459 1.00 146.83 ? 487 LYS H C   1 
ATOM 4252 O O   . LYS C 1 178 ? 190.632 221.309 198.663 1.00 146.83 ? 487 LYS H O   1 
ATOM 4253 C CB  . LYS C 1 178 ? 192.195 218.565 200.022 1.00 146.83 ? 487 LYS H CB  1 
ATOM 4254 C CG  . LYS C 1 178 ? 192.019 217.276 200.809 1.00 146.83 ? 487 LYS H CG  1 
ATOM 4255 C CD  . LYS C 1 178 ? 191.004 217.398 201.927 1.00 146.83 ? 487 LYS H CD  1 
ATOM 4256 C CE  . LYS C 1 178 ? 189.633 216.956 201.491 1.00 146.83 ? 487 LYS H CE  1 
ATOM 4257 N NZ  . LYS C 1 178 ? 188.689 216.983 202.630 1.00 146.83 ? 487 LYS H NZ  1 
ATOM 4258 N N   . GLY C 1 179 ? 192.390 220.352 197.649 1.00 154.54 ? 488 GLY H N   1 
ATOM 4259 C CA  . GLY C 1 179 ? 192.908 221.604 197.148 1.00 154.54 ? 488 GLY H CA  1 
ATOM 4260 C C   . GLY C 1 179 ? 192.169 222.150 195.950 1.00 154.54 ? 488 GLY H C   1 
ATOM 4261 O O   . GLY C 1 179 ? 191.626 223.256 196.010 1.00 154.54 ? 488 GLY H O   1 
ATOM 4262 N N   . CYS C 1 180 ? 192.142 221.392 194.856 1.00 149.69 ? 489 CYS H N   1 
ATOM 4263 C CA  . CYS C 1 180 ? 191.558 221.903 193.625 1.00 149.69 ? 489 CYS H CA  1 
ATOM 4264 C C   . CYS C 1 180 ? 190.077 222.196 193.819 1.00 149.69 ? 489 CYS H C   1 
ATOM 4265 O O   . CYS C 1 180 ? 189.327 221.380 194.363 1.00 149.69 ? 489 CYS H O   1 
ATOM 4266 C CB  . CYS C 1 180 ? 191.775 220.914 192.481 1.00 149.69 ? 489 CYS H CB  1 
ATOM 4267 S SG  . CYS C 1 180 ? 193.503 220.750 191.984 1.00 149.69 ? 489 CYS H SG  1 
ATOM 4268 N N   . LEU C 1 181 ? 189.667 223.379 193.374 1.00 106.70 ? 490 LEU H N   1 
ATOM 4269 C CA  . LEU C 1 181 ? 188.322 223.873 193.593 1.00 106.70 ? 490 LEU H CA  1 
ATOM 4270 C C   . LEU C 1 181 ? 187.698 224.435 192.328 1.00 106.70 ? 490 LEU H C   1 
ATOM 4271 O O   . LEU C 1 181 ? 186.492 224.695 192.316 1.00 106.70 ? 490 LEU H O   1 
ATOM 4272 C CB  . LEU C 1 181 ? 188.337 224.944 194.696 1.00 106.70 ? 490 LEU H CB  1 
ATOM 4273 C CG  . LEU C 1 181 ? 187.064 225.496 195.336 1.00 106.70 ? 490 LEU H CG  1 
ATOM 4274 C CD1 . LEU C 1 181 ? 187.329 225.789 196.800 1.00 106.70 ? 490 LEU H CD1 1 
ATOM 4275 C CD2 . LEU C 1 181 ? 186.616 226.763 194.632 1.00 106.70 ? 490 LEU H CD2 1 
ATOM 4276 N N   . LYS C 1 182 ? 188.474 224.604 191.263 1.00 95.82  ? 491 LYS H N   1 
ATOM 4277 C CA  . LYS C 1 182 ? 188.011 225.162 190.004 1.00 95.82  ? 491 LYS H CA  1 
ATOM 4278 C C   . LYS C 1 182 ? 187.594 224.088 188.997 1.00 95.82  ? 491 LYS H C   1 
ATOM 4279 O O   . LYS C 1 182 ? 187.310 224.409 187.842 1.00 95.82  ? 491 LYS H O   1 
ATOM 4280 C CB  . LYS C 1 182 ? 189.108 226.068 189.432 1.00 95.82  ? 491 LYS H CB  1 
ATOM 4281 C CG  . LYS C 1 182 ? 188.689 226.973 188.285 1.00 95.82  ? 491 LYS H CG  1 
ATOM 4282 C CD  . LYS C 1 182 ? 187.331 227.614 188.534 1.00 95.82  ? 491 LYS H CD  1 
ATOM 4283 C CE  . LYS C 1 182 ? 187.323 228.527 189.749 1.00 95.82  ? 491 LYS H CE  1 
ATOM 4284 N NZ  . LYS C 1 182 ? 185.964 229.084 189.984 1.00 95.82  ? 491 LYS H NZ  1 
ATOM 4285 N N   . LEU C 1 183 ? 187.546 222.825 189.406 1.00 102.59 ? 492 LEU H N   1 
ATOM 4286 C CA  . LEU C 1 183 ? 187.183 221.748 188.495 1.00 102.59 ? 492 LEU H CA  1 
ATOM 4287 C C   . LEU C 1 183 ? 185.747 221.903 188.011 1.00 102.59 ? 492 LEU H C   1 
ATOM 4288 O O   . LEU C 1 183 ? 184.875 222.375 188.745 1.00 102.59 ? 492 LEU H O   1 
ATOM 4289 C CB  . LEU C 1 183 ? 187.350 220.402 189.188 1.00 102.59 ? 492 LEU H CB  1 
ATOM 4290 C CG  . LEU C 1 183 ? 188.766 219.841 189.162 1.00 102.59 ? 492 LEU H CG  1 
ATOM 4291 C CD1 . LEU C 1 183 ? 188.902 218.685 190.133 1.00 102.59 ? 492 LEU H CD1 1 
ATOM 4292 C CD2 . LEU C 1 183 ? 189.136 219.425 187.763 1.00 102.59 ? 492 LEU H CD2 1 
ATOM 4293 N N   . GLN C 1 184 ? 185.499 221.514 186.768 1.00 107.86 ? 493 GLN H N   1 
ATOM 4294 C CA  . GLN C 1 184 ? 184.145 221.601 186.243 1.00 107.86 ? 493 GLN H CA  1 
ATOM 4295 C C   . GLN C 1 184 ? 183.618 220.300 185.664 1.00 107.86 ? 493 GLN H C   1 
ATOM 4296 O O   . GLN C 1 184 ? 182.447 219.975 185.871 1.00 107.86 ? 493 GLN H O   1 
ATOM 4297 C CB  . GLN C 1 184 ? 184.066 222.696 185.184 1.00 107.86 ? 493 GLN H CB  1 
ATOM 4298 C CG  . GLN C 1 184 ? 184.036 224.084 185.773 1.00 107.86 ? 493 GLN H CG  1 
ATOM 4299 C CD  . GLN C 1 184 ? 183.650 225.135 184.763 1.00 107.86 ? 493 GLN H CD  1 
ATOM 4300 O OE1 . GLN C 1 184 ? 183.415 224.832 183.595 1.00 107.86 ? 493 GLN H OE1 1 
ATOM 4301 N NE2 . GLN C 1 184 ? 183.600 226.384 185.200 1.00 107.86 ? 493 GLN H NE2 1 
ATOM 4302 N N   . ARG C 1 185 ? 184.431 219.543 184.940 1.00 87.34  ? 494 ARG H N   1 
ATOM 4303 C CA  . ARG C 1 185 ? 183.965 218.314 184.320 1.00 87.34  ? 494 ARG H CA  1 
ATOM 4304 C C   . ARG C 1 185 ? 184.788 217.138 184.825 1.00 87.34  ? 494 ARG H C   1 
ATOM 4305 O O   . ARG C 1 185 ? 186.010 217.122 184.668 1.00 87.34  ? 494 ARG H O   1 
ATOM 4306 C CB  . ARG C 1 185 ? 184.061 218.412 182.806 1.00 87.34  ? 494 ARG H CB  1 
ATOM 4307 C CG  . ARG C 1 185 ? 183.047 219.355 182.208 1.00 87.34  ? 494 ARG H CG  1 
ATOM 4308 C CD  . ARG C 1 185 ? 183.157 219.410 180.698 1.00 87.34  ? 494 ARG H CD  1 
ATOM 4309 N NE  . ARG C 1 185 ? 183.135 220.779 180.200 1.00 87.34  ? 494 ARG H NE  1 
ATOM 4310 C CZ  . ARG C 1 185 ? 182.043 221.522 180.098 1.00 87.34  ? 494 ARG H CZ  1 
ATOM 4311 N N   . ILE C 1 186 ? 184.113 216.146 185.410 1.00 87.94  ? 495 ILE H N   1 
ATOM 4312 C CA  . ILE C 1 186 ? 184.760 214.976 185.994 1.00 87.94  ? 495 ILE H CA  1 
ATOM 4313 C C   . ILE C 1 186 ? 184.300 213.733 185.245 1.00 87.94  ? 495 ILE H C   1 
ATOM 4314 O O   . ILE C 1 186 ? 183.098 213.468 185.144 1.00 87.94  ? 495 ILE H O   1 
ATOM 4315 C CB  . ILE C 1 186 ? 184.463 214.849 187.498 1.00 87.94  ? 495 ILE H CB  1 
ATOM 4316 C CG1 . ILE C 1 186 ? 182.965 214.767 187.751 1.00 87.94  ? 495 ILE H CG1 1 
ATOM 4317 C CG2 . ILE C 1 186 ? 185.015 216.034 188.235 1.00 87.94  ? 495 ILE H CG2 1 
ATOM 4318 C CD1 . ILE C 1 186 ? 182.603 214.431 189.157 1.00 87.94  ? 495 ILE H CD1 1 
ATOM 4319 N N   . TYR C 1 187 ? 185.257 212.974 184.717 1.00 100.33 ? 496 TYR H N   1 
ATOM 4320 C CA  . TYR C 1 187 ? 184.938 211.851 183.850 1.00 100.33 ? 496 TYR H CA  1 
ATOM 4321 C C   . TYR C 1 187 ? 185.910 210.705 184.090 1.00 100.33 ? 496 TYR H C   1 
ATOM 4322 O O   . TYR C 1 187 ? 187.128 210.900 184.130 1.00 100.33 ? 496 TYR H O   1 
ATOM 4323 C CB  . TYR C 1 187 ? 184.954 212.288 182.378 1.00 100.33 ? 496 TYR H CB  1 
ATOM 4324 C CG  . TYR C 1 187 ? 184.482 211.244 181.390 1.00 100.33 ? 496 TYR H CG  1 
ATOM 4325 C CD1 . TYR C 1 187 ? 185.377 210.378 180.775 1.00 100.33 ? 496 TYR H CD1 1 
ATOM 4326 C CD2 . TYR C 1 187 ? 183.135 211.106 181.097 1.00 100.33 ? 496 TYR H CD2 1 
ATOM 4327 C CE1 . TYR C 1 187 ? 184.947 209.429 179.870 1.00 100.33 ? 496 TYR H CE1 1 
ATOM 4328 C CE2 . TYR C 1 187 ? 182.697 210.159 180.202 1.00 100.33 ? 496 TYR H CE2 1 
ATOM 4329 C CZ  . TYR C 1 187 ? 183.605 209.320 179.593 1.00 100.33 ? 496 TYR H CZ  1 
ATOM 4330 N N   . MET C 1 188 ? 185.352 209.507 184.236 1.00 109.20 ? 497 MET H N   1 
ATOM 4331 C CA  . MET C 1 188 ? 186.110 208.301 184.515 1.00 109.20 ? 497 MET H CA  1 
ATOM 4332 C C   . MET C 1 188 ? 185.595 207.218 183.573 1.00 109.20 ? 497 MET H C   1 
ATOM 4333 O O   . MET C 1 188 ? 184.975 207.503 182.547 1.00 109.20 ? 497 MET H O   1 
ATOM 4334 C CB  . MET C 1 188 ? 185.944 207.878 185.977 1.00 109.20 ? 497 MET H CB  1 
ATOM 4335 C CG  . MET C 1 188 ? 186.500 208.855 187.007 1.00 109.20 ? 497 MET H CG  1 
ATOM 4336 S SD  . MET C 1 188 ? 188.270 209.137 186.984 1.00 109.20 ? 497 MET H SD  1 
ATOM 4337 C CE  . MET C 1 188 ? 188.408 210.480 188.159 1.00 109.20 ? 497 MET H CE  1 
ATOM 4338 N N   . GLN C 1 189 ? 185.867 205.966 183.914 1.00 100.86 ? 498 GLN H N   1 
ATOM 4339 C CA  . GLN C 1 189 ? 185.307 204.806 183.222 1.00 100.86 ? 498 GLN H CA  1 
ATOM 4340 C C   . GLN C 1 189 ? 185.072 203.710 184.247 1.00 100.86 ? 498 GLN H C   1 
ATOM 4341 O O   . GLN C 1 189 ? 184.909 203.961 185.446 1.00 100.86 ? 498 GLN H O   1 
ATOM 4342 C CB  . GLN C 1 189 ? 186.193 204.298 182.077 1.00 100.86 ? 498 GLN H CB  1 
ATOM 4343 C CG  . GLN C 1 189 ? 186.218 205.151 180.847 1.00 100.86 ? 498 GLN H CG  1 
ATOM 4344 C CD  . GLN C 1 189 ? 184.863 205.229 180.190 1.00 100.86 ? 498 GLN H CD  1 
ATOM 4345 O OE1 . GLN C 1 189 ? 184.256 206.292 180.126 1.00 100.86 ? 498 GLN H OE1 1 
ATOM 4346 N NE2 . GLN C 1 189 ? 184.365 204.091 179.726 1.00 100.86 ? 498 GLN H NE2 1 
ATOM 4347 N N   . GLU C 1 190 ? 185.045 202.474 183.758 1.00 116.53 ? 499 GLU H N   1 
ATOM 4348 C CA  . GLU C 1 190 ? 185.025 201.300 184.615 1.00 116.53 ? 499 GLU H CA  1 
ATOM 4349 C C   . GLU C 1 190 ? 186.362 201.224 185.344 1.00 116.53 ? 499 GLU H C   1 
ATOM 4350 O O   . GLU C 1 190 ? 187.134 200.274 185.195 1.00 116.53 ? 499 GLU H O   1 
ATOM 4351 C CB  . GLU C 1 190 ? 184.756 200.044 183.770 1.00 116.53 ? 499 GLU H CB  1 
ATOM 4352 C CG  . GLU C 1 190 ? 185.835 199.740 182.703 1.00 116.53 ? 499 GLU H CG  1 
ATOM 4353 C CD  . GLU C 1 190 ? 185.524 198.527 181.844 1.00 116.53 ? 499 GLU H CD  1 
ATOM 4354 O OE1 . GLU C 1 190 ? 184.464 197.902 182.047 1.00 116.53 ? 499 GLU H OE1 1 
ATOM 4355 O OE2 . GLU C 1 190 ? 186.345 198.201 180.962 1.00 116.53 ? 499 GLU H OE2 1 
ATOM 4356 N N   . ASN C 1 191 ? 186.620 202.227 186.169 1.00 126.85 ? 500 ASN H N   1 
ATOM 4357 C CA  . ASN C 1 191 ? 187.854 202.334 186.928 1.00 126.85 ? 500 ASN H CA  1 
ATOM 4358 C C   . ASN C 1 191 ? 187.608 201.562 188.215 1.00 126.85 ? 500 ASN H C   1 
ATOM 4359 O O   . ASN C 1 191 ? 186.849 202.011 189.079 1.00 126.85 ? 500 ASN H O   1 
ATOM 4360 C CB  . ASN C 1 191 ? 188.203 203.802 187.167 1.00 126.85 ? 500 ASN H CB  1 
ATOM 4361 C CG  . ASN C 1 191 ? 189.506 203.985 187.904 1.00 126.85 ? 500 ASN H CG  1 
ATOM 4362 O OD1 . ASN C 1 191 ? 190.027 203.062 188.519 1.00 126.85 ? 500 ASN H OD1 1 
ATOM 4363 N ND2 . ASN C 1 191 ? 190.067 205.182 187.807 1.00 126.85 ? 500 ASN H ND2 1 
ATOM 4364 N N   . LYS C 1 192 ? 188.216 200.385 188.317 1.00 127.09 ? 501 LYS H N   1 
ATOM 4365 C CA  . LYS C 1 192 ? 187.905 199.481 189.411 1.00 127.09 ? 501 LYS H CA  1 
ATOM 4366 C C   . LYS C 1 192 ? 188.430 200.014 190.739 1.00 127.09 ? 501 LYS H C   1 
ATOM 4367 O O   . LYS C 1 192 ? 189.336 200.850 190.804 1.00 127.09 ? 501 LYS H O   1 
ATOM 4368 C CB  . LYS C 1 192 ? 188.461 198.086 189.129 1.00 127.09 ? 501 LYS H CB  1 
ATOM 4369 C CG  . LYS C 1 192 ? 187.991 197.500 187.814 1.00 127.09 ? 501 LYS H CG  1 
ATOM 4370 C CD  . LYS C 1 192 ? 186.468 197.563 187.767 1.00 127.09 ? 501 LYS H CD  1 
ATOM 4371 C CE  . LYS C 1 192 ? 185.919 197.640 186.361 1.00 127.09 ? 501 LYS H CE  1 
ATOM 4372 N NZ  . LYS C 1 192 ? 184.551 198.225 186.369 1.00 127.09 ? 501 LYS H NZ  1 
ATOM 4373 N N   . LEU C 1 193 ? 187.820 199.509 191.810 1.00 125.33 ? 502 LEU H N   1 
ATOM 4374 C CA  . LEU C 1 193 ? 188.131 199.827 193.198 1.00 125.33 ? 502 LEU H CA  1 
ATOM 4375 C C   . LEU C 1 193 ? 187.786 201.264 193.570 1.00 125.33 ? 502 LEU H C   1 
ATOM 4376 O O   . LEU C 1 193 ? 188.194 201.736 194.637 1.00 125.33 ? 502 LEU H O   1 
ATOM 4377 C CB  . LEU C 1 193 ? 189.599 199.525 193.535 1.00 125.33 ? 502 LEU H CB  1 
ATOM 4378 C CG  . LEU C 1 193 ? 190.061 198.075 193.759 1.00 125.33 ? 502 LEU H CG  1 
ATOM 4379 C CD1 . LEU C 1 193 ? 189.679 197.116 192.631 1.00 125.33 ? 502 LEU H CD1 1 
ATOM 4380 C CD2 . LEU C 1 193 ? 191.567 198.022 194.011 1.00 125.33 ? 502 LEU H CD2 1 
ATOM 4381 N N   . VAL C 1 194 ? 187.035 201.972 192.732 1.00 115.77 ? 503 VAL H N   1 
ATOM 4382 C CA  . VAL C 1 194 ? 186.521 203.297 193.069 1.00 115.77 ? 503 VAL H CA  1 
ATOM 4383 C C   . VAL C 1 194 ? 185.403 203.099 194.087 1.00 115.77 ? 503 VAL H C   1 
ATOM 4384 O O   . VAL C 1 194 ? 184.282 202.726 193.738 1.00 115.77 ? 503 VAL H O   1 
ATOM 4385 C CB  . VAL C 1 194 ? 186.037 204.052 191.831 1.00 115.77 ? 503 VAL H CB  1 
ATOM 4386 C CG1 . VAL C 1 194 ? 185.348 205.337 192.237 1.00 115.77 ? 503 VAL H CG1 1 
ATOM 4387 C CG2 . VAL C 1 194 ? 187.203 204.384 190.928 1.00 115.77 ? 503 VAL H CG2 1 
ATOM 4388 N N   . THR C 1 195 ? 185.726 203.324 195.358 1.00 131.35 ? 504 THR H N   1 
ATOM 4389 C CA  . THR C 1 195 ? 184.810 203.050 196.457 1.00 131.35 ? 504 THR H CA  1 
ATOM 4390 C C   . THR C 1 195 ? 183.887 204.240 196.698 1.00 131.35 ? 504 THR H C   1 
ATOM 4391 O O   . THR C 1 195 ? 184.020 205.305 196.091 1.00 131.35 ? 504 THR H O   1 
ATOM 4392 C CB  . THR C 1 195 ? 185.588 202.713 197.724 1.00 131.35 ? 504 THR H CB  1 
ATOM 4393 O OG1 . THR C 1 195 ? 184.666 202.414 198.779 1.00 131.35 ? 504 THR H OG1 1 
ATOM 4394 C CG2 . THR C 1 195 ? 186.413 203.895 198.131 1.00 131.35 ? 504 THR H CG2 1 
ATOM 4395 N N   . ASP C 1 196 ? 182.930 204.063 197.609 1.00 132.85 ? 505 ASP H N   1 
ATOM 4396 C CA  . ASP C 1 196 ? 182.086 205.157 198.073 1.00 132.85 ? 505 ASP H CA  1 
ATOM 4397 C C   . ASP C 1 196 ? 182.863 206.259 198.762 1.00 132.85 ? 505 ASP H C   1 
ATOM 4398 O O   . ASP C 1 196 ? 182.443 207.415 198.698 1.00 132.85 ? 505 ASP H O   1 
ATOM 4399 C CB  . ASP C 1 196 ? 181.055 204.670 199.071 1.00 132.85 ? 505 ASP H CB  1 
ATOM 4400 C CG  . ASP C 1 196 ? 179.981 203.863 198.440 1.00 132.85 ? 505 ASP H CG  1 
ATOM 4401 O OD1 . ASP C 1 196 ? 179.733 204.071 197.238 1.00 132.85 ? 505 ASP H OD1 1 
ATOM 4402 O OD2 . ASP C 1 196 ? 179.391 203.024 199.146 1.00 132.85 ? 505 ASP H OD2 1 
ATOM 4403 N N   . GLN C 1 197 ? 183.989 205.950 199.395 1.00 153.90 ? 506 GLN H N   1 
ATOM 4404 C CA  . GLN C 1 197 ? 184.812 206.968 200.019 1.00 153.90 ? 506 GLN H CA  1 
ATOM 4405 C C   . GLN C 1 197 ? 185.647 207.700 198.976 1.00 153.90 ? 506 GLN H C   1 
ATOM 4406 O O   . GLN C 1 197 ? 186.483 208.544 199.305 1.00 153.90 ? 506 GLN H O   1 
ATOM 4407 C CB  . GLN C 1 197 ? 185.660 206.310 201.103 1.00 153.90 ? 506 GLN H CB  1 
ATOM 4408 C CG  . GLN C 1 197 ? 186.465 207.261 202.009 1.00 153.90 ? 506 GLN H CG  1 
ATOM 4409 C CD  . GLN C 1 197 ? 187.831 207.651 201.442 1.00 153.90 ? 506 GLN H CD  1 
ATOM 4410 O OE1 . GLN C 1 197 ? 188.455 206.894 200.702 1.00 153.90 ? 506 GLN H OE1 1 
ATOM 4411 N NE2 . GLN C 1 197 ? 188.294 208.857 201.796 1.00 153.90 ? 506 GLN H NE2 1 
ATOM 4412 N N   . SER C 1 198 ? 185.357 207.451 197.702 1.00 146.10 ? 507 SER H N   1 
ATOM 4413 C CA  . SER C 1 198 ? 185.898 208.227 196.603 1.00 146.10 ? 507 SER H CA  1 
ATOM 4414 C C   . SER C 1 198 ? 184.882 209.252 196.105 1.00 146.10 ? 507 SER H C   1 
ATOM 4415 O O   . SER C 1 198 ? 185.081 209.832 195.035 1.00 146.10 ? 507 SER H O   1 
ATOM 4416 C CB  . SER C 1 198 ? 186.274 207.283 195.455 1.00 146.10 ? 507 SER H CB  1 
ATOM 4417 O OG  . SER C 1 198 ? 187.302 206.395 195.843 1.00 146.10 ? 507 SER H OG  1 
ATOM 4418 N N   . VAL C 1 199 ? 183.775 209.448 196.828 1.00 153.43 ? 508 VAL H N   1 
ATOM 4419 C CA  . VAL C 1 199 ? 182.616 210.191 196.344 1.00 153.43 ? 508 VAL H CA  1 
ATOM 4420 C C   . VAL C 1 199 ? 182.177 211.265 197.336 1.00 153.43 ? 508 VAL H C   1 
ATOM 4421 O O   . VAL C 1 199 ? 182.088 212.450 196.991 1.00 153.43 ? 508 VAL H O   1 
ATOM 4422 C CB  . VAL C 1 199 ? 181.443 209.238 196.023 1.00 153.43 ? 508 VAL H CB  1 
ATOM 4423 C CG1 . VAL C 1 199 ? 180.181 210.023 195.666 1.00 153.43 ? 508 VAL H CG1 1 
ATOM 4424 C CG2 . VAL C 1 199 ? 181.844 208.274 194.905 1.00 153.43 ? 508 VAL H CG2 1 
ATOM 4425 N N   . LYS C 1 200 ? 181.865 210.866 198.567 1.00 159.05 ? 509 LYS H N   1 
ATOM 4426 C CA  . LYS C 1 200 ? 181.376 211.822 199.553 1.00 159.05 ? 509 LYS H CA  1 
ATOM 4427 C C   . LYS C 1 200 ? 182.431 212.868 199.878 1.00 159.05 ? 509 LYS H C   1 
ATOM 4428 O O   . LYS C 1 200 ? 182.117 214.055 200.023 1.00 159.05 ? 509 LYS H O   1 
ATOM 4429 C CB  . LYS C 1 200 ? 180.952 211.070 200.811 1.00 159.05 ? 509 LYS H CB  1 
ATOM 4430 C CG  . LYS C 1 200 ? 180.043 209.909 200.492 1.00 159.05 ? 509 LYS H CG  1 
ATOM 4431 C CD  . LYS C 1 200 ? 180.265 208.752 201.443 1.00 159.05 ? 509 LYS H CD  1 
ATOM 4432 C CE  . LYS C 1 200 ? 179.733 207.457 200.845 1.00 159.05 ? 509 LYS H CE  1 
ATOM 4433 N NZ  . LYS C 1 200 ? 179.655 206.378 201.858 1.00 159.05 ? 509 LYS H NZ  1 
ATOM 4434 N N   . ALA C 1 201 ? 183.690 212.444 199.996 1.00 161.60 ? 510 ALA H N   1 
ATOM 4435 C CA  . ALA C 1 201 ? 184.797 213.333 200.323 1.00 161.60 ? 510 ALA H CA  1 
ATOM 4436 C C   . ALA C 1 201 ? 185.305 214.123 199.122 1.00 161.60 ? 510 ALA H C   1 
ATOM 4437 O O   . ALA C 1 201 ? 186.474 214.529 199.117 1.00 161.60 ? 510 ALA H O   1 
ATOM 4438 C CB  . ALA C 1 201 ? 185.950 212.538 200.949 1.00 161.60 ? 510 ALA H CB  1 
ATOM 4439 N N   . PHE C 1 202 ? 184.475 214.316 198.096 1.00 150.46 ? 511 PHE H N   1 
ATOM 4440 C CA  . PHE C 1 202 ? 184.795 215.178 196.967 1.00 150.46 ? 511 PHE H CA  1 
ATOM 4441 C C   . PHE C 1 202 ? 183.800 216.312 196.750 1.00 150.46 ? 511 PHE H C   1 
ATOM 4442 O O   . PHE C 1 202 ? 184.218 217.411 196.369 1.00 150.46 ? 511 PHE H O   1 
ATOM 4443 C CB  . PHE C 1 202 ? 184.891 214.352 195.682 1.00 150.46 ? 511 PHE H CB  1 
ATOM 4444 C CG  . PHE C 1 202 ? 185.357 215.135 194.501 1.00 150.46 ? 511 PHE H CG  1 
ATOM 4445 C CD1 . PHE C 1 202 ? 186.679 215.481 194.363 1.00 150.46 ? 511 PHE H CD1 1 
ATOM 4446 C CD2 . PHE C 1 202 ? 184.467 215.526 193.526 1.00 150.46 ? 511 PHE H CD2 1 
ATOM 4447 C CE1 . PHE C 1 202 ? 187.102 216.205 193.284 1.00 150.46 ? 511 PHE H CE1 1 
ATOM 4448 C CE2 . PHE C 1 202 ? 184.892 216.250 192.439 1.00 150.46 ? 511 PHE H CE2 1 
ATOM 4449 C CZ  . PHE C 1 202 ? 186.215 216.588 192.321 1.00 150.46 ? 511 PHE H CZ  1 
ATOM 4450 N N   . ALA C 1 203 ? 182.507 216.086 196.989 1.00 159.97 ? 512 ALA H N   1 
ATOM 4451 C CA  . ALA C 1 203 ? 181.460 217.036 196.628 1.00 159.97 ? 512 ALA H CA  1 
ATOM 4452 C C   . ALA C 1 203 ? 181.283 218.133 197.663 1.00 159.97 ? 512 ALA H C   1 
ATOM 4453 O O   . ALA C 1 203 ? 180.379 218.963 197.529 1.00 159.97 ? 512 ALA H O   1 
ATOM 4454 C CB  . ALA C 1 203 ? 180.132 216.311 196.414 1.00 159.97 ? 512 ALA H CB  1 
ATOM 4455 N N   . GLU C 1 204 ? 182.121 218.142 198.696 1.00 173.39 ? 513 GLU H N   1 
ATOM 4456 C CA  . GLU C 1 204 ? 182.083 219.169 199.722 1.00 173.39 ? 513 GLU H CA  1 
ATOM 4457 C C   . GLU C 1 204 ? 183.020 220.333 199.443 1.00 173.39 ? 513 GLU H C   1 
ATOM 4458 O O   . GLU C 1 204 ? 183.094 221.253 200.263 1.00 173.39 ? 513 GLU H O   1 
ATOM 4459 C CB  . GLU C 1 204 ? 182.445 218.564 201.086 1.00 173.39 ? 513 GLU H CB  1 
ATOM 4460 C CG  . GLU C 1 204 ? 181.435 217.563 201.602 1.00 173.39 ? 513 GLU H CG  1 
ATOM 4461 C CD  . GLU C 1 204 ? 180.130 218.209 201.993 1.00 173.39 ? 513 GLU H CD  1 
ATOM 4462 O OE1 . GLU C 1 204 ? 180.154 219.364 202.464 1.00 173.39 ? 513 GLU H OE1 1 
ATOM 4463 O OE2 . GLU C 1 204 ? 179.082 217.554 201.831 1.00 173.39 ? 513 GLU H OE2 1 
ATOM 4464 N N   . HIS C 1 205 ? 183.742 220.309 198.327 1.00 144.80 ? 514 HIS H N   1 
ATOM 4465 C CA  . HIS C 1 205 ? 184.822 221.250 198.073 1.00 144.80 ? 514 HIS H CA  1 
ATOM 4466 C C   . HIS C 1 205 ? 184.597 222.103 196.835 1.00 144.80 ? 514 HIS H C   1 
ATOM 4467 O O   . HIS C 1 205 ? 184.952 223.285 196.824 1.00 144.80 ? 514 HIS H O   1 
ATOM 4468 C CB  . HIS C 1 205 ? 186.125 220.469 197.953 1.00 144.80 ? 514 HIS H CB  1 
ATOM 4469 C CG  . HIS C 1 205 ? 186.587 219.904 199.255 1.00 144.80 ? 514 HIS H CG  1 
ATOM 4470 N ND1 . HIS C 1 205 ? 187.147 220.679 200.245 1.00 144.80 ? 514 HIS H ND1 1 
ATOM 4471 C CD2 . HIS C 1 205 ? 186.520 218.647 199.750 1.00 144.80 ? 514 HIS H CD2 1 
ATOM 4472 C CE1 . HIS C 1 205 ? 187.440 219.915 201.283 1.00 144.80 ? 514 HIS H CE1 1 
ATOM 4473 N NE2 . HIS C 1 205 ? 187.063 218.680 201.009 1.00 144.80 ? 514 HIS H NE2 1 
ATOM 4474 N N   . CYS C 1 206 ? 184.045 221.520 195.774 1.00 134.09 ? 515 CYS H N   1 
ATOM 4475 C CA  . CYS C 1 206 ? 183.674 222.268 194.580 1.00 134.09 ? 515 CYS H CA  1 
ATOM 4476 C C   . CYS C 1 206 ? 182.176 222.134 194.347 1.00 134.09 ? 515 CYS H C   1 
ATOM 4477 O O   . CYS C 1 206 ? 181.695 221.027 194.070 1.00 134.09 ? 515 CYS H O   1 
ATOM 4478 C CB  . CYS C 1 206 ? 184.455 221.759 193.369 1.00 134.09 ? 515 CYS H CB  1 
ATOM 4479 S SG  . CYS C 1 206 ? 184.132 222.660 191.853 1.00 134.09 ? 515 CYS H SG  1 
ATOM 4480 N N   . PRO C 1 207 ? 181.393 223.209 194.480 1.00 132.71 ? 516 PRO H N   1 
ATOM 4481 C CA  . PRO C 1 207 ? 179.930 223.110 194.307 1.00 132.71 ? 516 PRO H CA  1 
ATOM 4482 C C   . PRO C 1 207 ? 179.414 223.493 192.925 1.00 132.71 ? 516 PRO H C   1 
ATOM 4483 O O   . PRO C 1 207 ? 178.190 223.537 192.749 1.00 132.71 ? 516 PRO H O   1 
ATOM 4484 C CB  . PRO C 1 207 ? 179.428 224.110 195.353 1.00 132.71 ? 516 PRO H CB  1 
ATOM 4485 C CG  . PRO C 1 207 ? 180.478 225.184 195.351 1.00 132.71 ? 516 PRO H CG  1 
ATOM 4486 C CD  . PRO C 1 207 ? 181.796 224.540 194.958 1.00 132.71 ? 516 PRO H CD  1 
ATOM 4487 N N   . GLU C 1 208 ? 180.290 223.765 191.960 1.00 114.90 ? 517 GLU H N   1 
ATOM 4488 C CA  . GLU C 1 208 ? 179.872 224.239 190.651 1.00 114.90 ? 517 GLU H CA  1 
ATOM 4489 C C   . GLU C 1 208 ? 179.983 223.165 189.572 1.00 114.90 ? 517 GLU H C   1 
ATOM 4490 O O   . GLU C 1 208 ? 180.057 223.496 188.388 1.00 114.90 ? 517 GLU H O   1 
ATOM 4491 C CB  . GLU C 1 208 ? 180.681 225.478 190.261 1.00 114.90 ? 517 GLU H CB  1 
ATOM 4492 C CG  . GLU C 1 208 ? 182.128 225.223 189.849 1.00 114.90 ? 517 GLU H CG  1 
ATOM 4493 C CD  . GLU C 1 208 ? 183.126 225.585 190.928 1.00 114.90 ? 517 GLU H CD  1 
ATOM 4494 O OE1 . GLU C 1 208 ? 182.695 225.966 192.034 1.00 114.90 ? 517 GLU H OE1 1 
ATOM 4495 O OE2 . GLU C 1 208 ? 184.344 225.503 190.663 1.00 114.90 ? 517 GLU H OE2 1 
ATOM 4496 N N   . LEU C 1 209 ? 179.974 221.891 189.956 1.00 105.06 ? 518 LEU H N   1 
ATOM 4497 C CA  . LEU C 1 209 ? 180.111 220.815 188.982 1.00 105.06 ? 518 LEU H CA  1 
ATOM 4498 C C   . LEU C 1 209 ? 178.936 220.797 188.016 1.00 105.06 ? 518 LEU H C   1 
ATOM 4499 O O   . LEU C 1 209 ? 177.836 221.258 188.325 1.00 105.06 ? 518 LEU H O   1 
ATOM 4500 C CB  . LEU C 1 209 ? 180.221 219.456 189.674 1.00 105.06 ? 518 LEU H CB  1 
ATOM 4501 C CG  . LEU C 1 209 ? 181.580 218.987 190.202 1.00 105.06 ? 518 LEU H CG  1 
ATOM 4502 C CD1 . LEU C 1 209 ? 182.561 218.807 189.055 1.00 105.06 ? 518 LEU H CD1 1 
ATOM 4503 C CD2 . LEU C 1 209 ? 182.145 219.921 191.238 1.00 105.06 ? 518 LEU H CD2 1 
ATOM 4504 N N   . GLN C 1 210 ? 179.192 220.285 186.823 1.00 90.14  ? 519 GLN H N   1 
ATOM 4505 C CA  . GLN C 1 210 ? 178.200 220.194 185.763 1.00 90.14  ? 519 GLN H CA  1 
ATOM 4506 C C   . GLN C 1 210 ? 178.129 218.815 185.135 1.00 90.14  ? 519 GLN H C   1 
ATOM 4507 O O   . GLN C 1 210 ? 177.034 218.285 184.933 1.00 90.14  ? 519 GLN H O   1 
ATOM 4508 C CB  . GLN C 1 210 ? 178.535 221.220 184.685 1.00 90.14  ? 519 GLN H CB  1 
ATOM 4509 C CG  . GLN C 1 210 ? 178.628 222.625 185.226 1.00 90.14  ? 519 GLN H CG  1 
ATOM 4510 C CD  . GLN C 1 210 ? 180.060 223.022 185.517 1.00 90.14  ? 519 GLN H CD  1 
ATOM 4511 O OE1 . GLN C 1 210 ? 180.823 222.240 186.087 1.00 90.14  ? 519 GLN H OE1 1 
ATOM 4512 N NE2 . GLN C 1 210 ? 180.432 224.238 185.136 1.00 90.14  ? 519 GLN H NE2 1 
ATOM 4513 N N   . TYR C 1 211 ? 179.276 218.227 184.823 1.00 95.28  ? 520 TYR H N   1 
ATOM 4514 C CA  . TYR C 1 211 ? 179.369 216.892 184.257 1.00 95.28  ? 520 TYR H CA  1 
ATOM 4515 C C   . TYR C 1 211 ? 180.006 215.995 185.301 1.00 95.28  ? 520 TYR H C   1 
ATOM 4516 O O   . TYR C 1 211 ? 181.135 216.253 185.731 1.00 95.28  ? 520 TYR H O   1 
ATOM 4517 C CB  . TYR C 1 211 ? 180.224 216.886 182.987 1.00 95.28  ? 520 TYR H CB  1 
ATOM 4518 C CG  . TYR C 1 211 ? 179.650 217.642 181.809 1.00 95.28  ? 520 TYR H CG  1 
ATOM 4519 C CD1 . TYR C 1 211 ? 179.713 219.029 181.752 1.00 95.28  ? 520 TYR H CD1 1 
ATOM 4520 C CD2 . TYR C 1 211 ? 179.063 216.973 180.744 1.00 95.28  ? 520 TYR H CD2 1 
ATOM 4521 C CE1 . TYR C 1 211 ? 179.203 219.727 180.673 1.00 95.28  ? 520 TYR H CE1 1 
ATOM 4522 C CE2 . TYR C 1 211 ? 178.545 217.666 179.660 1.00 95.28  ? 520 TYR H CE2 1 
ATOM 4523 C CZ  . TYR C 1 211 ? 178.619 219.042 179.632 1.00 95.28  ? 520 TYR H CZ  1 
ATOM 4524 N N   . VAL C 1 212 ? 179.299 214.944 185.703 1.00 67.89  ? 521 VAL H N   1 
ATOM 4525 C CA  . VAL C 1 212 ? 179.786 214.038 186.734 1.00 67.89  ? 521 VAL H CA  1 
ATOM 4526 C C   . VAL C 1 212 ? 179.873 212.655 186.115 1.00 67.89  ? 521 VAL H C   1 
ATOM 4527 O O   . VAL C 1 212 ? 178.844 211.998 185.924 1.00 67.89  ? 521 VAL H O   1 
ATOM 4528 C CB  . VAL C 1 212 ? 178.870 214.039 187.968 1.00 67.89  ? 521 VAL H CB  1 
ATOM 4529 C CG1 . VAL C 1 212 ? 179.089 212.817 188.813 1.00 67.89  ? 521 VAL H CG1 1 
ATOM 4530 C CG2 . VAL C 1 212 ? 179.106 215.277 188.791 1.00 67.89  ? 521 VAL H CG2 1 
ATOM 4531 N N   . GLY C 1 213 ? 181.092 212.207 185.815 1.00 94.29  ? 522 GLY H N   1 
ATOM 4532 C CA  . GLY C 1 213 ? 181.242 210.999 185.024 1.00 94.29  ? 522 GLY H CA  1 
ATOM 4533 C C   . GLY C 1 213 ? 182.004 209.885 185.707 1.00 94.29  ? 522 GLY H C   1 
ATOM 4534 O O   . GLY C 1 213 ? 183.220 209.965 185.903 1.00 94.29  ? 522 GLY H O   1 
ATOM 4535 N N   . PHE C 1 214 ? 181.285 208.837 186.089 1.00 86.03  ? 523 PHE H N   1 
ATOM 4536 C CA  . PHE C 1 214 ? 181.836 207.711 186.836 1.00 86.03  ? 523 PHE H CA  1 
ATOM 4537 C C   . PHE C 1 214 ? 181.182 206.394 186.422 1.00 86.03  ? 523 PHE H C   1 
ATOM 4538 O O   . PHE C 1 214 ? 180.854 205.553 187.258 1.00 86.03  ? 523 PHE H O   1 
ATOM 4539 C CB  . PHE C 1 214 ? 181.704 208.012 188.327 1.00 86.03  ? 523 PHE H CB  1 
ATOM 4540 C CG  . PHE C 1 214 ? 180.278 208.163 188.789 1.00 86.03  ? 523 PHE H CG  1 
ATOM 4541 C CD1 . PHE C 1 214 ? 179.673 209.403 188.768 1.00 86.03  ? 523 PHE H CD1 1 
ATOM 4542 C CD2 . PHE C 1 214 ? 179.527 207.088 189.207 1.00 86.03  ? 523 PHE H CD2 1 
ATOM 4543 C CE1 . PHE C 1 214 ? 178.362 209.572 189.159 1.00 86.03  ? 523 PHE H CE1 1 
ATOM 4544 C CE2 . PHE C 1 214 ? 178.194 207.252 189.596 1.00 86.03  ? 523 PHE H CE2 1 
ATOM 4545 C CZ  . PHE C 1 214 ? 177.626 208.500 189.588 1.00 86.03  ? 523 PHE H CZ  1 
ATOM 4546 N N   . MET C 1 215 ? 181.009 206.179 185.118 1.00 92.64  ? 524 MET H N   1 
ATOM 4547 C CA  . MET C 1 215 ? 180.285 205.006 184.632 1.00 92.64  ? 524 MET H CA  1 
ATOM 4548 C C   . MET C 1 215 ? 180.915 203.701 185.107 1.00 92.64  ? 524 MET H C   1 
ATOM 4549 O O   . MET C 1 215 ? 182.141 203.559 185.134 1.00 92.64  ? 524 MET H O   1 
ATOM 4550 C CB  . MET C 1 215 ? 180.224 205.013 183.103 1.00 92.64  ? 524 MET H CB  1 
ATOM 4551 C CG  . MET C 1 215 ? 181.589 204.973 182.410 1.00 92.64  ? 524 MET H CG  1 
ATOM 4552 S SD  . MET C 1 215 ? 181.450 205.407 180.671 1.00 92.64  ? 524 MET H SD  1 
ATOM 4553 C CE  . MET C 1 215 ? 181.290 207.178 180.770 1.00 92.64  ? 524 MET H CE  1 
ATOM 4554 N N   . GLY C 1 216 ? 180.065 202.750 185.493 1.00 107.78 ? 525 GLY H N   1 
ATOM 4555 C CA  . GLY C 1 216 ? 180.527 201.403 185.796 1.00 107.78 ? 525 GLY H CA  1 
ATOM 4556 C C   . GLY C 1 216 ? 181.545 201.312 186.907 1.00 107.78 ? 525 GLY H C   1 
ATOM 4557 O O   . GLY C 1 216 ? 182.569 200.643 186.737 1.00 107.78 ? 525 GLY H O   1 
ATOM 4558 N N   . CYS C 1 217 ? 181.308 201.979 188.035 1.00 115.67 ? 526 CYS H N   1 
ATOM 4559 C CA  . CYS C 1 217 ? 182.264 201.959 189.132 1.00 115.67 ? 526 CYS H CA  1 
ATOM 4560 C C   . CYS C 1 217 ? 181.741 201.158 190.322 1.00 115.67 ? 526 CYS H C   1 
ATOM 4561 O O   . CYS C 1 217 ? 180.638 200.606 190.308 1.00 115.67 ? 526 CYS H O   1 
ATOM 4562 C CB  . CYS C 1 217 ? 182.633 203.377 189.555 1.00 115.67 ? 526 CYS H CB  1 
ATOM 4563 S SG  . CYS C 1 217 ? 183.733 204.218 188.399 1.00 115.67 ? 526 CYS H SG  1 
ATOM 4564 N N   . SER C 1 218 ? 182.559 201.115 191.376 1.00 118.96 ? 527 SER H N   1 
ATOM 4565 C CA  . SER C 1 218 ? 182.386 200.237 192.528 1.00 118.96 ? 527 SER H CA  1 
ATOM 4566 C C   . SER C 1 218 ? 181.773 200.950 193.731 1.00 118.96 ? 527 SER H C   1 
ATOM 4567 O O   . SER C 1 218 ? 182.250 200.785 194.859 1.00 118.96 ? 527 SER H O   1 
ATOM 4568 C CB  . SER C 1 218 ? 183.729 199.622 192.911 1.00 118.96 ? 527 SER H CB  1 
ATOM 4569 O OG  . SER C 1 218 ? 183.603 198.819 194.067 1.00 118.96 ? 527 SER H OG  1 
ATOM 4570 N N   . VAL C 1 219 ? 180.752 201.766 193.511 1.00 126.00 ? 528 VAL H N   1 
ATOM 4571 C CA  . VAL C 1 219 ? 180.174 202.603 194.556 1.00 126.00 ? 528 VAL H CA  1 
ATOM 4572 C C   . VAL C 1 219 ? 178.743 202.165 194.848 1.00 126.00 ? 528 VAL H C   1 
ATOM 4573 O O   . VAL C 1 219 ? 178.141 201.409 194.076 1.00 126.00 ? 528 VAL H O   1 
ATOM 4574 C CB  . VAL C 1 219 ? 180.233 204.086 194.159 1.00 126.00 ? 528 VAL H CB  1 
ATOM 4575 C CG1 . VAL C 1 219 ? 181.662 204.575 194.220 1.00 126.00 ? 528 VAL H CG1 1 
ATOM 4576 C CG2 . VAL C 1 219 ? 179.685 204.290 192.766 1.00 126.00 ? 528 VAL H CG2 1 
ATOM 4577 N N   . THR C 1 220 ? 178.217 202.597 195.992 1.00 134.11 ? 529 THR H N   1 
ATOM 4578 C CA  . THR C 1 220 ? 176.867 202.262 196.421 1.00 134.11 ? 529 THR H CA  1 
ATOM 4579 C C   . THR C 1 220 ? 175.987 203.522 196.452 1.00 134.11 ? 529 THR H C   1 
ATOM 4580 O O   . THR C 1 220 ? 176.467 204.649 196.331 1.00 134.11 ? 529 THR H O   1 
ATOM 4581 C CB  . THR C 1 220 ? 176.933 201.561 197.784 1.00 134.11 ? 529 THR H CB  1 
ATOM 4582 O OG1 . THR C 1 220 ? 177.822 200.442 197.682 1.00 134.11 ? 529 THR H OG1 1 
ATOM 4583 C CG2 . THR C 1 220 ? 175.579 201.007 198.211 1.00 134.11 ? 529 THR H CG2 1 
ATOM 4584 N N   . SER C 1 221 ? 174.675 203.313 196.613 1.00 130.53 ? 530 SER H N   1 
ATOM 4585 C CA  . SER C 1 221 ? 173.688 204.388 196.540 1.00 130.53 ? 530 SER H CA  1 
ATOM 4586 C C   . SER C 1 221 ? 173.908 205.497 197.560 1.00 130.53 ? 530 SER H C   1 
ATOM 4587 O O   . SER C 1 221 ? 173.460 206.627 197.334 1.00 130.53 ? 530 SER H O   1 
ATOM 4588 C CB  . SER C 1 221 ? 172.287 203.815 196.735 1.00 130.53 ? 530 SER H CB  1 
ATOM 4589 O OG  . SER C 1 221 ? 171.338 204.856 196.868 1.00 130.53 ? 530 SER H OG  1 
ATOM 4590 N N   . LYS C 1 222 ? 174.567 205.209 198.680 1.00 135.29 ? 531 LYS H N   1 
ATOM 4591 C CA  . LYS C 1 222 ? 174.689 206.228 199.716 1.00 135.29 ? 531 LYS H CA  1 
ATOM 4592 C C   . LYS C 1 222 ? 175.474 207.439 199.231 1.00 135.29 ? 531 LYS H C   1 
ATOM 4593 O O   . LYS C 1 222 ? 175.135 208.575 199.581 1.00 135.29 ? 531 LYS H O   1 
ATOM 4594 C CB  . LYS C 1 222 ? 175.340 205.635 200.968 1.00 135.29 ? 531 LYS H CB  1 
ATOM 4595 C CG  . LYS C 1 222 ? 174.444 204.717 201.815 1.00 135.29 ? 531 LYS H CG  1 
ATOM 4596 C CD  . LYS C 1 222 ? 173.021 205.229 202.081 1.00 135.29 ? 531 LYS H CD  1 
ATOM 4597 C CE  . LYS C 1 222 ? 172.966 206.689 202.528 1.00 135.29 ? 531 LYS H CE  1 
ATOM 4598 N NZ  . LYS C 1 222 ? 171.581 207.109 202.866 1.00 135.29 ? 531 LYS H NZ  1 
ATOM 4599 N N   . GLY C 1 223 ? 176.507 207.227 198.420 1.00 132.70 ? 532 GLY H N   1 
ATOM 4600 C CA  . GLY C 1 223 ? 177.315 208.331 197.944 1.00 132.70 ? 532 GLY H CA  1 
ATOM 4601 C C   . GLY C 1 223 ? 176.565 209.226 196.982 1.00 132.70 ? 532 GLY H C   1 
ATOM 4602 O O   . GLY C 1 223 ? 176.697 210.450 197.030 1.00 132.70 ? 532 GLY H O   1 
ATOM 4603 N N   . VAL C 1 224 ? 175.764 208.619 196.104 1.00 156.63 ? 533 VAL H N   1 
ATOM 4604 C CA  . VAL C 1 224 ? 174.980 209.394 195.146 1.00 156.63 ? 533 VAL H CA  1 
ATOM 4605 C C   . VAL C 1 224 ? 173.804 210.075 195.831 1.00 156.63 ? 533 VAL H C   1 
ATOM 4606 O O   . VAL C 1 224 ? 173.257 211.058 195.315 1.00 156.63 ? 533 VAL H O   1 
ATOM 4607 C CB  . VAL C 1 224 ? 174.529 208.491 193.979 1.00 156.63 ? 533 VAL H CB  1 
ATOM 4608 C CG1 . VAL C 1 224 ? 173.595 207.423 194.465 1.00 156.63 ? 533 VAL H CG1 1 
ATOM 4609 C CG2 . VAL C 1 224 ? 173.855 209.307 192.896 1.00 156.63 ? 533 VAL H CG2 1 
ATOM 4610 N N   . ILE C 1 225 ? 173.396 209.583 197.001 1.00 151.82 ? 534 ILE H N   1 
ATOM 4611 C CA  . ILE C 1 225 ? 172.417 210.328 197.785 1.00 151.82 ? 534 ILE H CA  1 
ATOM 4612 C C   . ILE C 1 225 ? 172.977 211.696 198.162 1.00 151.82 ? 534 ILE H C   1 
ATOM 4613 O O   . ILE C 1 225 ? 172.253 212.699 198.179 1.00 151.82 ? 534 ILE H O   1 
ATOM 4614 C CB  . ILE C 1 225 ? 172.004 209.518 199.023 1.00 151.82 ? 534 ILE H CB  1 
ATOM 4615 C CG1 . ILE C 1 225 ? 171.235 208.279 198.583 1.00 151.82 ? 534 ILE H CG1 1 
ATOM 4616 C CG2 . ILE C 1 225 ? 171.148 210.357 199.948 1.00 151.82 ? 534 ILE H CG2 1 
ATOM 4617 C CD1 . ILE C 1 225 ? 170.821 207.377 199.710 1.00 151.82 ? 534 ILE H CD1 1 
ATOM 4618 N N   . HIS C 1 226 ? 174.282 211.760 198.439 1.00 159.79 ? 535 HIS H N   1 
ATOM 4619 C CA  . HIS C 1 226 ? 174.967 212.976 198.868 1.00 159.79 ? 535 HIS H CA  1 
ATOM 4620 C C   . HIS C 1 226 ? 174.998 214.076 197.815 1.00 159.79 ? 535 HIS H C   1 
ATOM 4621 O O   . HIS C 1 226 ? 174.908 215.255 198.177 1.00 159.79 ? 535 HIS H O   1 
ATOM 4622 C CB  . HIS C 1 226 ? 176.407 212.635 199.268 1.00 159.79 ? 535 HIS H CB  1 
ATOM 4623 C CG  . HIS C 1 226 ? 177.259 213.830 199.561 1.00 159.79 ? 535 HIS H CG  1 
ATOM 4624 N ND1 . HIS C 1 226 ? 178.577 213.915 199.168 1.00 159.79 ? 535 HIS H ND1 1 
ATOM 4625 C CD2 . HIS C 1 226 ? 176.988 214.985 200.214 1.00 159.79 ? 535 HIS H CD2 1 
ATOM 4626 C CE1 . HIS C 1 226 ? 179.078 215.073 199.556 1.00 159.79 ? 535 HIS H CE1 1 
ATOM 4627 N NE2 . HIS C 1 226 ? 178.135 215.741 200.193 1.00 159.79 ? 535 HIS H NE2 1 
ATOM 4628 N N   . LEU C 1 227 ? 175.098 213.735 196.530 1.00 150.70 ? 536 LEU H N   1 
ATOM 4629 C CA  . LEU C 1 227 ? 175.345 214.752 195.514 1.00 150.70 ? 536 LEU H CA  1 
ATOM 4630 C C   . LEU C 1 227 ? 174.194 215.732 195.364 1.00 150.70 ? 536 LEU H C   1 
ATOM 4631 O O   . LEU C 1 227 ? 174.302 216.673 194.571 1.00 150.70 ? 536 LEU H O   1 
ATOM 4632 C CB  . LEU C 1 227 ? 175.650 214.104 194.168 1.00 150.70 ? 536 LEU H CB  1 
ATOM 4633 C CG  . LEU C 1 227 ? 177.104 213.662 193.979 1.00 150.70 ? 536 LEU H CG  1 
ATOM 4634 C CD1 . LEU C 1 227 ? 178.026 214.871 194.006 1.00 150.70 ? 536 LEU H CD1 1 
ATOM 4635 C CD2 . LEU C 1 227 ? 177.551 212.621 194.986 1.00 150.70 ? 536 LEU H CD2 1 
ATOM 4636 N N   . THR C 1 228 ? 173.107 215.539 196.105 1.00 148.59 ? 537 THR H N   1 
ATOM 4637 C CA  . THR C 1 228 ? 172.014 216.498 196.145 1.00 148.59 ? 537 THR H CA  1 
ATOM 4638 C C   . THR C 1 228 ? 172.438 217.843 196.722 1.00 148.59 ? 537 THR H C   1 
ATOM 4639 O O   . THR C 1 228 ? 171.642 218.788 196.696 1.00 148.59 ? 537 THR H O   1 
ATOM 4640 C CB  . THR C 1 228 ? 170.865 215.916 196.970 1.00 148.59 ? 537 THR H CB  1 
ATOM 4641 O OG1 . THR C 1 228 ? 169.725 216.771 196.878 1.00 148.59 ? 537 THR H OG1 1 
ATOM 4642 C CG2 . THR C 1 228 ? 171.274 215.791 198.427 1.00 148.59 ? 537 THR H CG2 1 
ATOM 4643 N N   . LYS C 1 229 ? 173.658 217.944 197.254 1.00 133.50 ? 538 LYS H N   1 
ATOM 4644 C CA  . LYS C 1 229 ? 174.107 219.170 197.901 1.00 133.50 ? 538 LYS H CA  1 
ATOM 4645 C C   . LYS C 1 229 ? 174.298 220.303 196.897 1.00 133.50 ? 538 LYS H C   1 
ATOM 4646 O O   . LYS C 1 229 ? 173.587 221.312 196.939 1.00 133.50 ? 538 LYS H O   1 
ATOM 4647 C CB  . LYS C 1 229 ? 175.398 218.898 198.666 1.00 133.50 ? 538 LYS H CB  1 
ATOM 4648 C CG  . LYS C 1 229 ? 175.135 218.518 200.092 1.00 133.50 ? 538 LYS H CG  1 
ATOM 4649 C CD  . LYS C 1 229 ? 176.365 218.657 200.933 1.00 133.50 ? 538 LYS H CD  1 
ATOM 4650 C CE  . LYS C 1 229 ? 176.034 218.414 202.389 1.00 133.50 ? 538 LYS H CE  1 
ATOM 4651 N NZ  . LYS C 1 229 ? 177.215 218.647 203.257 1.00 133.50 ? 538 LYS H NZ  1 
ATOM 4652 N N   . LEU C 1 230 ? 175.266 220.160 195.994 1.00 137.51 ? 539 LEU H N   1 
ATOM 4653 C CA  . LEU C 1 230 ? 175.522 221.209 195.017 1.00 137.51 ? 539 LEU H CA  1 
ATOM 4654 C C   . LEU C 1 230 ? 174.374 221.284 194.017 1.00 137.51 ? 539 LEU H C   1 
ATOM 4655 O O   . LEU C 1 230 ? 173.775 220.274 193.641 1.00 137.51 ? 539 LEU H O   1 
ATOM 4656 C CB  . LEU C 1 230 ? 176.851 220.969 194.304 1.00 137.51 ? 539 LEU H CB  1 
ATOM 4657 C CG  . LEU C 1 230 ? 177.001 219.678 193.501 1.00 137.51 ? 539 LEU H CG  1 
ATOM 4658 C CD1 . LEU C 1 230 ? 176.570 219.874 192.057 1.00 137.51 ? 539 LEU H CD1 1 
ATOM 4659 C CD2 . LEU C 1 230 ? 178.428 219.171 193.579 1.00 137.51 ? 539 LEU H CD2 1 
ATOM 4660 N N   . ARG C 1 231 ? 174.075 222.504 193.577 1.00 137.29 ? 540 ARG H N   1 
ATOM 4661 C CA  . ARG C 1 231 ? 172.828 222.787 192.877 1.00 137.29 ? 540 ARG H CA  1 
ATOM 4662 C C   . ARG C 1 231 ? 173.090 223.412 191.517 1.00 137.29 ? 540 ARG H C   1 
ATOM 4663 O O   . ARG C 1 231 ? 172.280 224.181 190.994 1.00 137.29 ? 540 ARG H O   1 
ATOM 4664 C CB  . ARG C 1 231 ? 171.943 223.691 193.728 1.00 137.29 ? 540 ARG H CB  1 
ATOM 4665 C CG  . ARG C 1 231 ? 171.005 222.921 194.630 1.00 137.29 ? 540 ARG H CG  1 
ATOM 4666 C CD  . ARG C 1 231 ? 170.444 223.812 195.714 1.00 137.29 ? 540 ARG H CD  1 
ATOM 4667 N NE  . ARG C 1 231 ? 170.438 223.129 197.000 1.00 137.29 ? 540 ARG H NE  1 
ATOM 4668 C CZ  . ARG C 1 231 ? 170.998 223.604 198.103 1.00 137.29 ? 540 ARG H CZ  1 
ATOM 4669 N N   . ASN C 1 232 ? 174.221 223.067 190.914 1.00 102.62 ? 541 ASN H N   1 
ATOM 4670 C CA  . ASN C 1 232 ? 174.516 223.518 189.564 1.00 102.62 ? 541 ASN H CA  1 
ATOM 4671 C C   . ASN C 1 232 ? 174.875 222.343 188.670 1.00 102.62 ? 541 ASN H C   1 
ATOM 4672 O O   . ASN C 1 232 ? 175.325 222.556 187.539 1.00 102.62 ? 541 ASN H O   1 
ATOM 4673 C CB  . ASN C 1 232 ? 175.648 224.549 189.567 1.00 102.62 ? 541 ASN H CB  1 
ATOM 4674 C CG  . ASN C 1 232 ? 175.594 225.473 188.370 1.00 102.62 ? 541 ASN H CG  1 
ATOM 4675 O OD1 . ASN C 1 232 ? 174.701 225.367 187.532 1.00 102.62 ? 541 ASN H OD1 1 
ATOM 4676 N ND2 . ASN C 1 232 ? 176.549 226.390 188.285 1.00 102.62 ? 541 ASN H ND2 1 
ATOM 4677 N N   . LEU C 1 233 ? 174.693 221.117 189.147 1.00 91.53  ? 542 LEU H N   1 
ATOM 4678 C CA  . LEU C 1 233 ? 175.031 219.946 188.360 1.00 91.53  ? 542 LEU H CA  1 
ATOM 4679 C C   . LEU C 1 233 ? 174.170 219.890 187.108 1.00 91.53  ? 542 LEU H C   1 
ATOM 4680 O O   . LEU C 1 233 ? 172.964 220.132 187.156 1.00 91.53  ? 542 LEU H O   1 
ATOM 4681 C CB  . LEU C 1 233 ? 174.839 218.691 189.199 1.00 91.53  ? 542 LEU H CB  1 
ATOM 4682 C CG  . LEU C 1 233 ? 175.423 217.446 188.568 1.00 91.53  ? 542 LEU H CG  1 
ATOM 4683 C CD1 . LEU C 1 233 ? 176.814 217.794 188.128 1.00 91.53  ? 542 LEU H CD1 1 
ATOM 4684 C CD2 . LEU C 1 233 ? 175.460 216.336 189.588 1.00 91.53  ? 542 LEU H CD2 1 
ATOM 4685 N N   . SER C 1 234 ? 174.792 219.571 185.979 1.00 89.47  ? 543 SER H N   1 
ATOM 4686 C CA  . SER C 1 234 ? 174.119 219.685 184.693 1.00 89.47  ? 543 SER H CA  1 
ATOM 4687 C C   . SER C 1 234 ? 173.865 218.341 184.037 1.00 89.47  ? 543 SER H C   1 
ATOM 4688 O O   . SER C 1 234 ? 172.758 218.100 183.541 1.00 89.47  ? 543 SER H O   1 
ATOM 4689 C CB  . SER C 1 234 ? 174.941 220.574 183.753 1.00 89.47  ? 543 SER H CB  1 
ATOM 4690 O OG  . SER C 1 234 ? 174.303 220.703 182.497 1.00 89.47  ? 543 SER H OG  1 
ATOM 4691 N N   . SER C 1 235 ? 174.859 217.463 184.003 1.00 86.88  ? 544 SER H N   1 
ATOM 4692 C CA  . SER C 1 235 ? 174.724 216.167 183.359 1.00 86.88  ? 544 SER H CA  1 
ATOM 4693 C C   . SER C 1 235 ? 175.259 215.081 184.278 1.00 86.88  ? 544 SER H C   1 
ATOM 4694 O O   . SER C 1 235 ? 176.313 215.247 184.899 1.00 86.88  ? 544 SER H O   1 
ATOM 4695 C CB  . SER C 1 235 ? 175.463 216.134 182.035 1.00 86.88  ? 544 SER H CB  1 
ATOM 4696 O OG  . SER C 1 235 ? 175.448 214.826 181.496 1.00 86.88  ? 544 SER H OG  1 
ATOM 4697 N N   . LEU C 1 236 ? 174.538 213.966 184.353 1.00 76.69  ? 545 LEU H N   1 
ATOM 4698 C CA  . LEU C 1 236 ? 174.857 212.891 185.278 1.00 76.69  ? 545 LEU H CA  1 
ATOM 4699 C C   . LEU C 1 236 ? 175.130 211.592 184.537 1.00 76.69  ? 545 LEU H C   1 
ATOM 4700 O O   . LEU C 1 236 ? 174.378 211.191 183.647 1.00 76.69  ? 545 LEU H O   1 
ATOM 4701 C CB  . LEU C 1 236 ? 173.727 212.678 186.278 1.00 76.69  ? 545 LEU H CB  1 
ATOM 4702 C CG  . LEU C 1 236 ? 174.108 211.736 187.414 1.00 76.69  ? 545 LEU H CG  1 
ATOM 4703 C CD1 . LEU C 1 236 ? 175.323 212.271 188.159 1.00 76.69  ? 545 LEU H CD1 1 
ATOM 4704 C CD2 . LEU C 1 236 ? 172.929 211.554 188.356 1.00 76.69  ? 545 LEU H CD2 1 
ATOM 4705 N N   . ASP C 1 237 ? 176.185 210.909 184.962 1.00 83.96  ? 546 ASP H N   1 
ATOM 4706 C CA  . ASP C 1 237 ? 176.794 209.811 184.221 1.00 83.96  ? 546 ASP H CA  1 
ATOM 4707 C C   . ASP C 1 237 ? 176.905 208.569 185.094 1.00 83.96  ? 546 ASP H C   1 
ATOM 4708 O O   . ASP C 1 237 ? 177.974 207.973 185.242 1.00 83.96  ? 546 ASP H O   1 
ATOM 4709 C CB  . ASP C 1 237 ? 178.153 210.244 183.685 1.00 83.96  ? 546 ASP H CB  1 
ATOM 4710 C CG  . ASP C 1 237 ? 178.740 209.273 182.701 1.00 83.96  ? 546 ASP H CG  1 
ATOM 4711 O OD1 . ASP C 1 237 ? 178.104 208.242 182.432 1.00 83.96  ? 546 ASP H OD1 1 
ATOM 4712 O OD2 . ASP C 1 237 ? 179.851 209.541 182.203 1.00 83.96  ? 546 ASP H OD2 1 
ATOM 4713 N N   . LEU C 1 238 ? 175.790 208.159 185.700 1.00 102.95 ? 547 LEU H N   1 
ATOM 4714 C CA  . LEU C 1 238 ? 175.772 206.932 186.495 1.00 102.95 ? 547 LEU H CA  1 
ATOM 4715 C C   . LEU C 1 238 ? 175.599 205.759 185.529 1.00 102.95 ? 547 LEU H C   1 
ATOM 4716 O O   . LEU C 1 238 ? 174.656 205.685 184.734 1.00 102.95 ? 547 LEU H O   1 
ATOM 4717 C CB  . LEU C 1 238 ? 174.675 206.963 187.566 1.00 102.95 ? 547 LEU H CB  1 
ATOM 4718 C CG  . LEU C 1 238 ? 173.176 206.852 187.241 1.00 102.95 ? 547 LEU H CG  1 
ATOM 4719 C CD1 . LEU C 1 238 ? 172.764 205.391 187.249 1.00 102.95 ? 547 LEU H CD1 1 
ATOM 4720 C CD2 . LEU C 1 238 ? 172.338 207.608 188.234 1.00 102.95 ? 547 LEU H CD2 1 
ATOM 4721 N N   . ARG C 1 239 ? 176.551 204.840 185.589 1.00 110.31 ? 548 ARG H N   1 
ATOM 4722 C CA  . ARG C 1 239 ? 176.398 203.515 185.017 1.00 110.31 ? 548 ARG H CA  1 
ATOM 4723 C C   . ARG C 1 239 ? 176.873 202.473 186.015 1.00 110.31 ? 548 ARG H C   1 
ATOM 4724 O O   . ARG C 1 239 ? 177.925 202.631 186.641 1.00 110.31 ? 548 ARG H O   1 
ATOM 4725 C CB  . ARG C 1 239 ? 177.155 203.399 183.703 1.00 110.31 ? 548 ARG H CB  1 
ATOM 4726 C CG  . ARG C 1 239 ? 176.520 204.231 182.634 1.00 110.31 ? 548 ARG H CG  1 
ATOM 4727 C CD  . ARG C 1 239 ? 177.129 203.990 181.280 1.00 110.31 ? 548 ARG H CD  1 
ATOM 4728 N NE  . ARG C 1 239 ? 177.183 205.230 180.524 1.00 110.31 ? 548 ARG H NE  1 
ATOM 4729 C CZ  . ARG C 1 239 ? 178.284 205.738 179.997 1.00 110.31 ? 548 ARG H CZ  1 
ATOM 4730 N N   . HIS C 1 240 ? 176.062 201.428 186.177 1.00 140.46 ? 549 HIS H N   1 
ATOM 4731 C CA  . HIS C 1 240 ? 176.375 200.280 187.021 1.00 140.46 ? 549 HIS H CA  1 
ATOM 4732 C C   . HIS C 1 240 ? 176.521 200.687 188.491 1.00 140.46 ? 549 HIS H C   1 
ATOM 4733 O O   . HIS C 1 240 ? 177.574 200.540 189.113 1.00 140.46 ? 549 HIS H O   1 
ATOM 4734 C CB  . HIS C 1 240 ? 177.621 199.574 186.486 1.00 140.46 ? 549 HIS H CB  1 
ATOM 4735 C CG  . HIS C 1 240 ? 177.511 199.203 185.041 1.00 140.46 ? 549 HIS H CG  1 
ATOM 4736 N ND1 . HIS C 1 240 ? 178.587 198.780 184.289 1.00 140.46 ? 549 HIS H ND1 1 
ATOM 4737 C CD2 . HIS C 1 240 ? 176.447 199.211 184.205 1.00 140.46 ? 549 HIS H CD2 1 
ATOM 4738 C CE1 . HIS C 1 240 ? 178.186 198.534 183.054 1.00 140.46 ? 549 HIS H CE1 1 
ATOM 4739 N NE2 . HIS C 1 240 ? 176.892 198.788 182.978 1.00 140.46 ? 549 HIS H NE2 1 
ATOM 4740 N N   . ILE C 1 241 ? 175.426 201.218 189.032 1.00 146.47 ? 550 ILE H N   1 
ATOM 4741 C CA  . ILE C 1 241 ? 175.301 201.540 190.448 1.00 146.47 ? 550 ILE H CA  1 
ATOM 4742 C C   . ILE C 1 241 ? 174.424 200.480 191.100 1.00 146.47 ? 550 ILE H C   1 
ATOM 4743 O O   . ILE C 1 241 ? 173.744 199.693 190.434 1.00 146.47 ? 550 ILE H O   1 
ATOM 4744 C CB  . ILE C 1 241 ? 174.703 202.945 190.677 1.00 146.47 ? 550 ILE H CB  1 
ATOM 4745 C CG1 . ILE C 1 241 ? 174.863 203.409 192.133 1.00 146.47 ? 550 ILE H CG1 1 
ATOM 4746 C CG2 . ILE C 1 241 ? 173.219 202.927 190.337 1.00 146.47 ? 550 ILE H CG2 1 
ATOM 4747 C CD1 . ILE C 1 241 ? 176.280 203.629 192.563 1.00 146.47 ? 550 ILE H CD1 1 
ATOM 4748 N N   . THR C 1 242 ? 174.427 200.480 192.431 1.00 165.82 ? 551 THR H N   1 
ATOM 4749 C CA  . THR C 1 242 ? 173.626 199.554 193.220 1.00 165.82 ? 551 THR H CA  1 
ATOM 4750 C C   . THR C 1 242 ? 172.382 200.284 193.725 1.00 165.82 ? 551 THR H C   1 
ATOM 4751 O O   . THR C 1 242 ? 172.313 200.752 194.862 1.00 165.82 ? 551 THR H O   1 
ATOM 4752 C CB  . THR C 1 242 ? 174.465 198.996 194.363 1.00 165.82 ? 551 THR H CB  1 
ATOM 4753 O OG1 . THR C 1 242 ? 175.151 200.074 195.008 1.00 165.82 ? 551 THR H OG1 1 
ATOM 4754 C CG2 . THR C 1 242 ? 175.506 198.027 193.822 1.00 165.82 ? 551 THR H CG2 1 
ATOM 4755 N N   . GLU C 1 243 ? 171.386 200.382 192.844 1.00 194.14 ? 552 GLU H N   1 
ATOM 4756 C CA  . GLU C 1 243 ? 170.017 200.785 193.179 1.00 194.14 ? 552 GLU H CA  1 
ATOM 4757 C C   . GLU C 1 243 ? 169.957 202.163 193.852 1.00 194.14 ? 552 GLU H C   1 
ATOM 4758 O O   . GLU C 1 243 ? 169.732 202.305 195.055 1.00 194.14 ? 552 GLU H O   1 
ATOM 4759 C CB  . GLU C 1 243 ? 169.313 199.718 194.028 1.00 194.14 ? 552 GLU H CB  1 
ATOM 4760 C CG  . GLU C 1 243 ? 167.885 200.101 194.457 1.00 194.14 ? 552 GLU H CG  1 
ATOM 4761 C CD  . GLU C 1 243 ? 167.068 200.735 193.333 1.00 194.14 ? 552 GLU H CD  1 
ATOM 4762 O OE1 . GLU C 1 243 ? 167.152 200.267 192.177 1.00 194.14 ? 552 GLU H OE1 1 
ATOM 4763 O OE2 . GLU C 1 243 ? 166.352 201.722 193.604 1.00 194.14 ? 552 GLU H OE2 1 
ATOM 4764 N N   . LEU C 1 244 ? 170.214 203.186 193.044 1.00 205.10 ? 553 LEU H N   1 
ATOM 4765 C CA  . LEU C 1 244 ? 169.766 204.524 193.409 1.00 205.10 ? 553 LEU H CA  1 
ATOM 4766 C C   . LEU C 1 244 ? 168.242 204.509 193.529 1.00 205.10 ? 553 LEU H C   1 
ATOM 4767 O O   . LEU C 1 244 ? 167.537 204.223 192.559 1.00 205.10 ? 553 LEU H O   1 
ATOM 4768 C CB  . LEU C 1 244 ? 170.233 205.536 192.358 1.00 205.10 ? 553 LEU H CB  1 
ATOM 4769 C CG  . LEU C 1 244 ? 169.788 207.005 192.314 1.00 205.10 ? 553 LEU H CG  1 
ATOM 4770 C CD1 . LEU C 1 244 ? 170.365 207.849 193.423 1.00 205.10 ? 553 LEU H CD1 1 
ATOM 4771 C CD2 . LEU C 1 244 ? 170.173 207.604 190.984 1.00 205.10 ? 553 LEU H CD2 1 
ATOM 4772 N N   . ASP C 1 245 ? 167.737 204.793 194.727 1.00 223.89 ? 554 ASP H N   1 
ATOM 4773 C CA  . ASP C 1 245 ? 166.326 204.596 195.026 1.00 223.89 ? 554 ASP H CA  1 
ATOM 4774 C C   . ASP C 1 245 ? 165.464 205.692 194.403 1.00 223.89 ? 554 ASP H C   1 
ATOM 4775 O O   . ASP C 1 245 ? 165.961 206.694 193.884 1.00 223.89 ? 554 ASP H O   1 
ATOM 4776 C CB  . ASP C 1 245 ? 166.099 204.555 196.536 1.00 223.89 ? 554 ASP H CB  1 
ATOM 4777 C CG  . ASP C 1 245 ? 164.879 203.739 196.922 1.00 223.89 ? 554 ASP H CG  1 
ATOM 4778 O OD1 . ASP C 1 245 ? 163.783 204.027 196.403 1.00 223.89 ? 554 ASP H OD1 1 
ATOM 4779 O OD2 . ASP C 1 245 ? 165.015 202.814 197.750 1.00 223.89 ? 554 ASP H OD2 1 
ATOM 4780 N N   . ASN C 1 246 ? 164.144 205.480 194.454 1.00 248.86 ? 555 ASN H N   1 
ATOM 4781 C CA  . ASN C 1 246 ? 163.213 206.474 193.925 1.00 248.86 ? 555 ASN H CA  1 
ATOM 4782 C C   . ASN C 1 246 ? 163.189 207.725 194.795 1.00 248.86 ? 555 ASN H C   1 
ATOM 4783 O O   . ASN C 1 246 ? 163.076 208.845 194.283 1.00 248.86 ? 555 ASN H O   1 
ATOM 4784 C CB  . ASN C 1 246 ? 161.808 205.877 193.799 1.00 248.86 ? 555 ASN H CB  1 
ATOM 4785 C CG  . ASN C 1 246 ? 161.039 205.876 195.114 1.00 248.86 ? 555 ASN H CG  1 
ATOM 4786 O OD1 . ASN C 1 246 ? 161.611 205.676 196.187 1.00 248.86 ? 555 ASN H OD1 1 
ATOM 4787 N ND2 . ASN C 1 246 ? 159.732 206.107 195.033 1.00 248.86 ? 555 ASN H ND2 1 
ATOM 4788 N N   . GLU C 1 247 ? 163.290 207.556 196.114 1.00 274.88 ? 556 GLU H N   1 
ATOM 4789 C CA  . GLU C 1 247 ? 163.370 208.709 197.004 1.00 274.88 ? 556 GLU H CA  1 
ATOM 4790 C C   . GLU C 1 247 ? 164.628 209.520 196.713 1.00 274.88 ? 556 GLU H C   1 
ATOM 4791 O O   . GLU C 1 247 ? 164.615 210.759 196.752 1.00 274.88 ? 556 GLU H O   1 
ATOM 4792 C CB  . GLU C 1 247 ? 163.357 208.228 198.458 1.00 274.88 ? 556 GLU H CB  1 
ATOM 4793 C CG  . GLU C 1 247 ? 163.471 209.319 199.506 1.00 274.88 ? 556 GLU H CG  1 
ATOM 4794 C CD  . GLU C 1 247 ? 162.277 210.248 199.503 1.00 274.88 ? 556 GLU H CD  1 
ATOM 4795 O OE1 . GLU C 1 247 ? 161.139 209.749 199.376 1.00 274.88 ? 556 GLU H OE1 1 
ATOM 4796 O OE2 . GLU C 1 247 ? 162.474 211.474 199.632 1.00 274.88 ? 556 GLU H OE2 1 
ATOM 4797 N N   . THR C 1 248 ? 165.725 208.825 196.413 1.00 232.40 ? 557 THR H N   1 
ATOM 4798 C CA  . THR C 1 248 ? 166.992 209.489 196.149 1.00 232.40 ? 557 THR H CA  1 
ATOM 4799 C C   . THR C 1 248 ? 166.913 210.349 194.894 1.00 232.40 ? 557 THR H C   1 
ATOM 4800 O O   . THR C 1 248 ? 167.362 211.501 194.894 1.00 232.40 ? 557 THR H O   1 
ATOM 4801 C CB  . THR C 1 248 ? 168.086 208.435 196.021 1.00 232.40 ? 557 THR H CB  1 
ATOM 4802 O OG1 . THR C 1 248 ? 167.755 207.542 194.951 1.00 232.40 ? 557 THR H OG1 1 
ATOM 4803 C CG2 . THR C 1 248 ? 168.159 207.622 197.293 1.00 232.40 ? 557 THR H CG2 1 
ATOM 4804 N N   . VAL C 1 249 ? 166.333 209.811 193.817 1.00 209.88 ? 558 VAL H N   1 
ATOM 4805 C CA  . VAL C 1 249 ? 166.168 210.601 192.600 1.00 209.88 ? 558 VAL H CA  1 
ATOM 4806 C C   . VAL C 1 249 ? 165.156 211.719 192.826 1.00 209.88 ? 558 VAL H C   1 
ATOM 4807 O O   . VAL C 1 249 ? 165.307 212.828 192.297 1.00 209.88 ? 558 VAL H O   1 
ATOM 4808 C CB  . VAL C 1 249 ? 165.789 209.702 191.404 1.00 209.88 ? 558 VAL H CB  1 
ATOM 4809 C CG1 . VAL C 1 249 ? 166.776 208.566 191.264 1.00 209.88 ? 558 VAL H CG1 1 
ATOM 4810 C CG2 . VAL C 1 249 ? 164.374 209.170 191.521 1.00 209.88 ? 558 VAL H CG2 1 
ATOM 4811 N N   . MET C 1 250 ? 164.129 211.455 193.637 1.00 220.50 ? 559 MET H N   1 
ATOM 4812 C CA  . MET C 1 250 ? 163.184 212.494 194.024 1.00 220.50 ? 559 MET H CA  1 
ATOM 4813 C C   . MET C 1 250 ? 163.912 213.701 194.596 1.00 220.50 ? 559 MET H C   1 
ATOM 4814 O O   . MET C 1 250 ? 163.723 214.828 194.124 1.00 220.50 ? 559 MET H O   1 
ATOM 4815 C CB  . MET C 1 250 ? 162.200 211.923 195.052 1.00 220.50 ? 559 MET H CB  1 
ATOM 4816 C CG  . MET C 1 250 ? 160.949 212.751 195.412 1.00 220.50 ? 559 MET H CG  1 
ATOM 4817 S SD  . MET C 1 250 ? 159.607 212.775 194.203 1.00 220.50 ? 559 MET H SD  1 
ATOM 4818 C CE  . MET C 1 250 ? 159.624 214.475 193.659 1.00 220.50 ? 559 MET H CE  1 
ATOM 4819 N N   . GLU C 1 251 ? 164.779 213.478 195.589 1.00 206.83 ? 560 GLU H N   1 
ATOM 4820 C CA  . GLU C 1 251 ? 165.499 214.591 196.208 1.00 206.83 ? 560 GLU H CA  1 
ATOM 4821 C C   . GLU C 1 251 ? 166.539 215.191 195.273 1.00 206.83 ? 560 GLU H C   1 
ATOM 4822 O O   . GLU C 1 251 ? 166.730 216.411 195.257 1.00 206.83 ? 560 GLU H O   1 
ATOM 4823 C CB  . GLU C 1 251 ? 166.158 214.163 197.517 1.00 206.83 ? 560 GLU H CB  1 
ATOM 4824 C CG  . GLU C 1 251 ? 165.189 214.035 198.668 1.00 206.83 ? 560 GLU H CG  1 
ATOM 4825 C CD  . GLU C 1 251 ? 164.559 215.369 199.029 1.00 206.83 ? 560 GLU H CD  1 
ATOM 4826 O OE1 . GLU C 1 251 ? 165.222 216.413 198.856 1.00 206.83 ? 560 GLU H OE1 1 
ATOM 4827 O OE2 . GLU C 1 251 ? 163.396 215.376 199.476 1.00 206.83 ? 560 GLU H OE2 1 
ATOM 4828 N N   . ILE C 1 252 ? 167.239 214.357 194.504 1.00 165.56 ? 561 ILE H N   1 
ATOM 4829 C CA  . ILE C 1 252 ? 168.299 214.893 193.662 1.00 165.56 ? 561 ILE H CA  1 
ATOM 4830 C C   . ILE C 1 252 ? 167.709 215.746 192.548 1.00 165.56 ? 561 ILE H C   1 
ATOM 4831 O O   . ILE C 1 252 ? 168.378 216.641 192.022 1.00 165.56 ? 561 ILE H O   1 
ATOM 4832 C CB  . ILE C 1 252 ? 169.181 213.756 193.119 1.00 165.56 ? 561 ILE H CB  1 
ATOM 4833 C CG1 . ILE C 1 252 ? 170.514 214.307 192.641 1.00 165.56 ? 561 ILE H CG1 1 
ATOM 4834 C CG2 . ILE C 1 252 ? 168.523 213.077 191.946 1.00 165.56 ? 561 ILE H CG2 1 
ATOM 4835 C CD1 . ILE C 1 252 ? 171.532 213.236 192.427 1.00 165.56 ? 561 ILE H CD1 1 
ATOM 4836 N N   . VAL C 1 253 ? 166.450 215.500 192.176 1.00 169.60 ? 562 VAL H N   1 
ATOM 4837 C CA  . VAL C 1 253 ? 165.833 216.321 191.143 1.00 169.60 ? 562 VAL H CA  1 
ATOM 4838 C C   . VAL C 1 253 ? 165.097 217.517 191.741 1.00 169.60 ? 562 VAL H C   1 
ATOM 4839 O O   . VAL C 1 253 ? 165.144 218.616 191.176 1.00 169.60 ? 562 VAL H O   1 
ATOM 4840 C CB  . VAL C 1 253 ? 164.907 215.464 190.268 1.00 169.60 ? 562 VAL H CB  1 
ATOM 4841 C CG1 . VAL C 1 253 ? 164.225 216.328 189.220 1.00 169.60 ? 562 VAL H CG1 1 
ATOM 4842 C CG2 . VAL C 1 253 ? 165.705 214.362 189.608 1.00 169.60 ? 562 VAL H CG2 1 
ATOM 4843 N N   . LYS C 1 254 ? 164.410 217.348 192.879 1.00 201.65 ? 563 LYS H N   1 
ATOM 4844 C CA  . LYS C 1 254 ? 163.765 218.497 193.509 1.00 201.65 ? 563 LYS H CA  1 
ATOM 4845 C C   . LYS C 1 254 ? 164.782 219.499 194.039 1.00 201.65 ? 563 LYS H C   1 
ATOM 4846 O O   . LYS C 1 254 ? 164.483 220.695 194.126 1.00 201.65 ? 563 LYS H O   1 
ATOM 4847 C CB  . LYS C 1 254 ? 162.843 218.061 194.647 1.00 201.65 ? 563 LYS H CB  1 
ATOM 4848 C CG  . LYS C 1 254 ? 161.627 218.972 194.800 1.00 201.65 ? 563 LYS H CG  1 
ATOM 4849 C CD  . LYS C 1 254 ? 160.750 218.608 195.987 1.00 201.65 ? 563 LYS H CD  1 
ATOM 4850 C CE  . LYS C 1 254 ? 160.007 217.302 195.768 1.00 201.65 ? 563 LYS H CE  1 
ATOM 4851 N NZ  . LYS C 1 254 ? 159.124 216.996 196.927 1.00 201.65 ? 563 LYS H NZ  1 
ATOM 4852 N N   . ARG C 1 255 ? 165.975 219.037 194.399 1.00 176.32 ? 564 ARG H N   1 
ATOM 4853 C CA  . ARG C 1 255 ? 167.038 219.920 194.858 1.00 176.32 ? 564 ARG H CA  1 
ATOM 4854 C C   . ARG C 1 255 ? 167.772 220.543 193.678 1.00 176.32 ? 564 ARG H C   1 
ATOM 4855 O O   . ARG C 1 255 ? 167.833 221.769 193.546 1.00 176.32 ? 564 ARG H O   1 
ATOM 4856 C CB  . ARG C 1 255 ? 168.023 219.141 195.732 1.00 176.32 ? 564 ARG H CB  1 
ATOM 4857 C CG  . ARG C 1 255 ? 167.581 218.909 197.158 1.00 176.32 ? 564 ARG H CG  1 
ATOM 4858 C CD  . ARG C 1 255 ? 168.617 219.462 198.113 1.00 176.32 ? 564 ARG H CD  1 
ATOM 4859 N NE  . ARG C 1 255 ? 168.531 218.849 199.432 1.00 176.32 ? 564 ARG H NE  1 
ATOM 4860 C CZ  . ARG C 1 255 ? 167.680 217.886 199.757 1.00 176.32 ? 564 ARG H CZ  1 
ATOM 4861 N N   . CYS C 1 256 ? 168.330 219.700 192.811 1.00 155.31 ? 565 CYS H N   1 
ATOM 4862 C CA  . CYS C 1 256 ? 169.057 220.161 191.636 1.00 155.31 ? 565 CYS H CA  1 
ATOM 4863 C C   . CYS C 1 256 ? 168.055 220.337 190.496 1.00 155.31 ? 565 CYS H C   1 
ATOM 4864 O O   . CYS C 1 256 ? 167.816 219.444 189.682 1.00 155.31 ? 565 CYS H O   1 
ATOM 4865 C CB  . CYS C 1 256 ? 170.157 219.176 191.276 1.00 155.31 ? 565 CYS H CB  1 
ATOM 4866 S SG  . CYS C 1 256 ? 171.299 218.838 192.629 1.00 155.31 ? 565 CYS H SG  1 
ATOM 4867 N N   . LYS C 1 257 ? 167.436 221.518 190.473 1.00 145.36 ? 566 LYS H N   1 
ATOM 4868 C CA  . LYS C 1 257 ? 166.429 221.789 189.455 1.00 145.36 ? 566 LYS H CA  1 
ATOM 4869 C C   . LYS C 1 257 ? 167.032 221.725 188.062 1.00 145.36 ? 566 LYS H C   1 
ATOM 4870 O O   . LYS C 1 257 ? 166.479 221.066 187.176 1.00 145.36 ? 566 LYS H O   1 
ATOM 4871 C CB  . LYS C 1 257 ? 165.792 223.157 189.691 1.00 145.36 ? 566 LYS H CB  1 
ATOM 4872 C CG  . LYS C 1 257 ? 164.658 223.160 190.699 1.00 145.36 ? 566 LYS H CG  1 
ATOM 4873 C CD  . LYS C 1 257 ? 165.190 223.019 192.109 1.00 145.36 ? 566 LYS H CD  1 
ATOM 4874 C CE  . LYS C 1 257 ? 165.971 224.249 192.525 1.00 145.36 ? 566 LYS H CE  1 
ATOM 4875 N NZ  . LYS C 1 257 ? 166.460 224.133 193.925 1.00 145.36 ? 566 LYS H NZ  1 
ATOM 4876 N N   . ASN C 1 258 ? 168.181 222.357 187.869 1.00 111.55 ? 567 ASN H N   1 
ATOM 4877 C CA  . ASN C 1 258 ? 168.882 222.354 186.591 1.00 111.55 ? 567 ASN H CA  1 
ATOM 4878 C C   . ASN C 1 258 ? 169.596 221.019 186.465 1.00 111.55 ? 567 ASN H C   1 
ATOM 4879 O O   . ASN C 1 258 ? 170.386 220.629 187.321 1.00 111.55 ? 567 ASN H O   1 
ATOM 4880 C CB  . ASN C 1 258 ? 169.839 223.536 186.517 1.00 111.55 ? 567 ASN H CB  1 
ATOM 4881 C CG  . ASN C 1 258 ? 170.897 223.502 187.607 1.00 111.55 ? 567 ASN H CG  1 
ATOM 4882 O OD1 . ASN C 1 258 ? 171.898 222.795 187.503 1.00 111.55 ? 567 ASN H OD1 1 
ATOM 4883 N ND2 . ASN C 1 258 ? 170.660 224.249 188.679 1.00 111.55 ? 567 ASN H ND2 1 
ATOM 4884 N N   . LEU C 1 259 ? 169.263 220.273 185.415 1.00 103.26 ? 568 LEU H N   1 
ATOM 4885 C CA  . LEU C 1 259 ? 169.921 219.005 185.137 1.00 103.26 ? 568 LEU H CA  1 
ATOM 4886 C C   . LEU C 1 259 ? 169.567 218.586 183.721 1.00 103.26 ? 568 LEU H C   1 
ATOM 4887 O O   . LEU C 1 259 ? 168.403 218.304 183.430 1.00 103.26 ? 568 LEU H O   1 
ATOM 4888 C CB  . LEU C 1 259 ? 169.493 217.922 186.128 1.00 103.26 ? 568 LEU H CB  1 
ATOM 4889 C CG  . LEU C 1 259 ? 170.389 216.691 186.149 1.00 103.26 ? 568 LEU H CG  1 
ATOM 4890 C CD1 . LEU C 1 259 ? 171.810 217.129 186.409 1.00 103.26 ? 568 LEU H CD1 1 
ATOM 4891 C CD2 . LEU C 1 259 ? 169.935 215.718 187.205 1.00 103.26 ? 568 LEU H CD2 1 
ATOM 4892 N N   . SER C 1 260 ? 170.568 218.533 182.849 1.00 99.59  ? 569 SER H N   1 
ATOM 4893 C CA  . SER C 1 260 ? 170.328 218.308 181.431 1.00 99.59  ? 569 SER H CA  1 
ATOM 4894 C C   . SER C 1 260 ? 170.210 216.827 181.090 1.00 99.59  ? 569 SER H C   1 
ATOM 4895 O O   . SER C 1 260 ? 169.182 216.392 180.561 1.00 99.59  ? 569 SER H O   1 
ATOM 4896 C CB  . SER C 1 260 ? 171.444 218.961 180.607 1.00 99.59  ? 569 SER H CB  1 
ATOM 4897 O OG  . SER C 1 260 ? 171.168 218.872 179.222 1.00 99.59  ? 569 SER H OG  1 
ATOM 4898 N N   . SER C 1 261 ? 171.239 216.038 181.390 1.00 99.97  ? 570 SER H N   1 
ATOM 4899 C CA  . SER C 1 261 ? 171.285 214.647 180.964 1.00 99.97  ? 570 SER H CA  1 
ATOM 4900 C C   . SER C 1 261 ? 171.651 213.739 182.125 1.00 99.97  ? 570 SER H C   1 
ATOM 4901 O O   . SER C 1 261 ? 172.632 213.984 182.832 1.00 99.97  ? 570 SER H O   1 
ATOM 4902 C CB  . SER C 1 261 ? 172.292 214.443 179.836 1.00 99.97  ? 570 SER H CB  1 
ATOM 4903 O OG  . SER C 1 261 ? 173.608 214.652 180.292 1.00 99.97  ? 570 SER H OG  1 
ATOM 4904 N N   . LEU C 1 262 ? 170.862 212.685 182.301 1.00 116.57 ? 571 LEU H N   1 
ATOM 4905 C CA  . LEU C 1 262 ? 171.156 211.586 183.208 1.00 116.57 ? 571 LEU H CA  1 
ATOM 4906 C C   . LEU C 1 262 ? 171.281 210.327 182.366 1.00 116.57 ? 571 LEU H C   1 
ATOM 4907 O O   . LEU C 1 262 ? 170.494 210.126 181.437 1.00 116.57 ? 571 LEU H O   1 
ATOM 4908 C CB  . LEU C 1 262 ? 170.056 211.453 184.265 1.00 116.57 ? 571 LEU H CB  1 
ATOM 4909 C CG  . LEU C 1 262 ? 168.607 211.326 183.771 1.00 116.57 ? 571 LEU H CG  1 
ATOM 4910 C CD1 . LEU C 1 262 ? 168.210 209.894 183.441 1.00 116.57 ? 571 LEU H CD1 1 
ATOM 4911 C CD2 . LEU C 1 262 ? 167.627 211.936 184.762 1.00 116.57 ? 571 LEU H CD2 1 
ATOM 4912 N N   . ASN C 1 263 ? 172.270 209.490 182.669 1.00 100.52 ? 572 ASN H N   1 
ATOM 4913 C CA  . ASN C 1 263 ? 172.448 208.289 181.860 1.00 100.52 ? 572 ASN H CA  1 
ATOM 4914 C C   . ASN C 1 263 ? 171.641 207.108 182.387 1.00 100.52 ? 572 ASN H C   1 
ATOM 4915 O O   . ASN C 1 263 ? 170.739 206.622 181.703 1.00 100.52 ? 572 ASN H O   1 
ATOM 4916 C CB  . ASN C 1 263 ? 173.927 207.916 181.756 1.00 100.52 ? 572 ASN H CB  1 
ATOM 4917 C CG  . ASN C 1 263 ? 174.723 208.916 180.953 1.00 100.52 ? 572 ASN H CG  1 
ATOM 4918 O OD1 . ASN C 1 263 ? 174.245 209.453 179.961 1.00 100.52 ? 572 ASN H OD1 1 
ATOM 4919 N ND2 . ASN C 1 263 ? 175.966 209.129 181.344 1.00 100.52 ? 572 ASN H ND2 1 
ATOM 4920 N N   . LEU C 1 264 ? 171.935 206.652 183.605 1.00 113.85 ? 573 LEU H N   1 
ATOM 4921 C CA  . LEU C 1 264 ? 171.401 205.398 184.135 1.00 113.85 ? 573 LEU H CA  1 
ATOM 4922 C C   . LEU C 1 264 ? 171.465 204.283 183.099 1.00 113.85 ? 573 LEU H C   1 
ATOM 4923 O O   . LEU C 1 264 ? 170.553 203.457 182.992 1.00 113.85 ? 573 LEU H O   1 
ATOM 4924 C CB  . LEU C 1 264 ? 169.971 205.565 184.677 1.00 113.85 ? 573 LEU H CB  1 
ATOM 4925 C CG  . LEU C 1 264 ? 168.751 206.151 183.965 1.00 113.85 ? 573 LEU H CG  1 
ATOM 4926 C CD1 . LEU C 1 264 ? 168.036 205.128 183.111 1.00 113.85 ? 573 LEU H CD1 1 
ATOM 4927 C CD2 . LEU C 1 264 ? 167.805 206.687 185.015 1.00 113.85 ? 573 LEU H CD2 1 
ATOM 4928 N N   . CYS C 1 265 ? 172.558 204.245 182.348 1.00 128.30 ? 574 CYS H N   1 
ATOM 4929 C CA  . CYS C 1 265 ? 172.760 203.214 181.350 1.00 128.30 ? 574 CYS H CA  1 
ATOM 4930 C C   . CYS C 1 265 ? 173.127 201.889 182.006 1.00 128.30 ? 574 CYS H C   1 
ATOM 4931 O O   . CYS C 1 265 ? 174.025 201.807 182.849 1.00 128.30 ? 574 CYS H O   1 
ATOM 4932 C CB  . CYS C 1 265 ? 173.852 203.630 180.370 1.00 128.30 ? 574 CYS H CB  1 
ATOM 4933 S SG  . CYS C 1 265 ? 174.386 202.360 179.204 1.00 128.30 ? 574 CYS H SG  1 
ATOM 4934 N N   . LEU C 1 266 ? 172.418 200.844 181.586 1.00 154.26 ? 575 LEU H N   1 
ATOM 4935 C CA  . LEU C 1 266 ? 172.664 199.466 182.006 1.00 154.26 ? 575 LEU H CA  1 
ATOM 4936 C C   . LEU C 1 266 ? 172.435 199.256 183.497 1.00 154.26 ? 575 LEU H C   1 
ATOM 4937 O O   . LEU C 1 266 ? 173.272 198.661 184.183 1.00 154.26 ? 575 LEU H O   1 
ATOM 4938 C CB  . LEU C 1 266 ? 174.074 199.027 181.627 1.00 154.26 ? 575 LEU H CB  1 
ATOM 4939 C CG  . LEU C 1 266 ? 174.253 198.968 180.123 1.00 154.26 ? 575 LEU H CG  1 
ATOM 4940 C CD1 . LEU C 1 266 ? 175.700 198.667 179.828 1.00 154.26 ? 575 LEU H CD1 1 
ATOM 4941 C CD2 . LEU C 1 266 ? 173.314 197.939 179.508 1.00 154.26 ? 575 LEU H CD2 1 
ATOM 4942 N N   . ASN C 1 267 ? 171.317 199.747 184.013 1.00 176.56 ? 576 ASN H N   1 
ATOM 4943 C CA  . ASN C 1 267 ? 170.894 199.449 185.371 1.00 176.56 ? 576 ASN H CA  1 
ATOM 4944 C C   . ASN C 1 267 ? 169.767 198.435 185.304 1.00 176.56 ? 576 ASN H C   1 
ATOM 4945 O O   . ASN C 1 267 ? 168.797 198.627 184.565 1.00 176.56 ? 576 ASN H O   1 
ATOM 4946 C CB  . ASN C 1 267 ? 170.434 200.707 186.105 1.00 176.56 ? 576 ASN H CB  1 
ATOM 4947 C CG  . ASN C 1 267 ? 171.520 201.299 186.977 1.00 176.56 ? 576 ASN H CG  1 
ATOM 4948 O OD1 . ASN C 1 267 ? 172.682 200.896 186.895 1.00 176.56 ? 576 ASN H OD1 1 
ATOM 4949 N ND2 . ASN C 1 267 ? 171.150 202.252 187.826 1.00 176.56 ? 576 ASN H ND2 1 
ATOM 4950 N N   . TRP C 1 268 ? 169.913 197.347 186.055 1.00 203.77 ? 577 TRP H N   1 
ATOM 4951 C CA  . TRP C 1 268 ? 168.934 196.269 186.053 1.00 203.77 ? 577 TRP H CA  1 
ATOM 4952 C C   . TRP C 1 268 ? 167.953 196.378 187.213 1.00 203.77 ? 577 TRP H C   1 
ATOM 4953 O O   . TRP C 1 268 ? 166.816 195.907 187.112 1.00 203.77 ? 577 TRP H O   1 
ATOM 4954 C CB  . TRP C 1 268 ? 169.656 194.921 186.086 1.00 203.77 ? 577 TRP H CB  1 
ATOM 4955 C CG  . TRP C 1 268 ? 170.585 194.729 184.924 1.00 203.77 ? 577 TRP H CG  1 
ATOM 4956 C CD1 . TRP C 1 268 ? 170.224 194.504 183.633 1.00 203.77 ? 577 TRP H CD1 1 
ATOM 4957 C CD2 . TRP C 1 268 ? 172.021 194.754 184.965 1.00 203.77 ? 577 TRP H CD2 1 
ATOM 4958 N NE1 . TRP C 1 268 ? 171.332 194.379 182.843 1.00 203.77 ? 577 TRP H NE1 1 
ATOM 4959 C CE2 . TRP C 1 268 ? 172.459 194.523 183.607 1.00 203.77 ? 577 TRP H CE2 1 
ATOM 4960 C CE3 . TRP C 1 268 ? 172.948 194.948 186.035 1.00 203.77 ? 577 TRP H CE3 1 
ATOM 4961 C CZ2 . TRP C 1 268 ? 173.798 194.465 183.200 1.00 203.77 ? 577 TRP H CZ2 1 
ATOM 4962 C CZ3 . TRP C 1 268 ? 174.334 194.934 185.881 1.00 203.77 ? 577 TRP H CZ3 1 
ATOM 4963 N N   . ILE C 1 269 ? 168.376 196.989 188.321 1.00 198.99 ? 578 ILE H N   1 
ATOM 4964 C CA  . ILE C 1 269 ? 167.563 197.040 189.534 1.00 198.99 ? 578 ILE H CA  1 
ATOM 4965 C C   . ILE C 1 269 ? 166.548 198.175 189.547 1.00 198.99 ? 578 ILE H C   1 
ATOM 4966 O O   . ILE C 1 269 ? 165.671 198.201 190.421 1.00 198.99 ? 578 ILE H O   1 
ATOM 4967 C CB  . ILE C 1 269 ? 168.538 197.116 190.723 1.00 198.99 ? 578 ILE H CB  1 
ATOM 4968 C CG1 . ILE C 1 269 ? 167.828 196.863 192.059 1.00 198.99 ? 578 ILE H CG1 1 
ATOM 4969 C CG2 . ILE C 1 269 ? 169.302 198.425 190.683 1.00 198.99 ? 578 ILE H CG2 1 
ATOM 4970 C CD1 . ILE C 1 269 ? 167.291 195.459 192.199 1.00 198.99 ? 578 ILE H CD1 1 
ATOM 4971 N N   . ILE C 1 270 ? 166.633 199.119 188.610 1.00 192.59 ? 579 ILE H N   1 
ATOM 4972 C CA  . ILE C 1 270 ? 165.708 200.248 188.606 1.00 192.59 ? 579 ILE H CA  1 
ATOM 4973 C C   . ILE C 1 270 ? 164.319 199.785 188.191 1.00 192.59 ? 579 ILE H C   1 
ATOM 4974 O O   . ILE C 1 270 ? 164.165 198.794 187.467 1.00 192.59 ? 579 ILE H O   1 
ATOM 4975 C CB  . ILE C 1 270 ? 166.220 201.349 187.673 1.00 192.59 ? 579 ILE H CB  1 
ATOM 4976 C CG1 . ILE C 1 270 ? 166.285 200.813 186.248 1.00 192.59 ? 579 ILE H CG1 1 
ATOM 4977 C CG2 . ILE C 1 270 ? 167.582 201.818 188.136 1.00 192.59 ? 579 ILE H CG2 1 
ATOM 4978 C CD1 . ILE C 1 270 ? 166.543 201.868 185.227 1.00 192.59 ? 579 ILE H CD1 1 
ATOM 4979 N N   . ASN C 1 271 ? 163.296 200.505 188.655 1.00 235.98 ? 580 ASN H N   1 
ATOM 4980 C CA  . ASN C 1 271 ? 161.906 200.170 188.379 1.00 235.98 ? 580 ASN H CA  1 
ATOM 4981 C C   . ASN C 1 271 ? 161.275 201.200 187.441 1.00 235.98 ? 580 ASN H C   1 
ATOM 4982 O O   . ASN C 1 271 ? 161.918 202.160 187.006 1.00 235.98 ? 580 ASN H O   1 
ATOM 4983 C CB  . ASN C 1 271 ? 161.119 200.070 189.682 1.00 235.98 ? 580 ASN H CB  1 
ATOM 4984 C CG  . ASN C 1 271 ? 161.158 201.356 190.488 1.00 235.98 ? 580 ASN H CG  1 
ATOM 4985 O OD1 . ASN C 1 271 ? 161.704 202.363 190.045 1.00 235.98 ? 580 ASN H OD1 1 
ATOM 4986 N ND2 . ASN C 1 271 ? 160.570 201.326 191.676 1.00 235.98 ? 580 ASN H ND2 1 
ATOM 4987 N N   . ASP C 1 272 ? 159.986 201.015 187.143 1.00 248.04 ? 581 ASP H N   1 
ATOM 4988 C CA  . ASP C 1 272 ? 159.259 201.941 186.281 1.00 248.04 ? 581 ASP H CA  1 
ATOM 4989 C C   . ASP C 1 272 ? 158.794 203.190 187.021 1.00 248.04 ? 581 ASP H C   1 
ATOM 4990 O O   . ASP C 1 272 ? 158.553 204.223 186.388 1.00 248.04 ? 581 ASP H O   1 
ATOM 4991 C CB  . ASP C 1 272 ? 158.052 201.236 185.658 1.00 248.04 ? 581 ASP H CB  1 
ATOM 4992 C CG  . ASP C 1 272 ? 157.083 200.698 186.699 1.00 248.04 ? 581 ASP H CG  1 
ATOM 4993 O OD1 . ASP C 1 272 ? 157.390 200.775 187.907 1.00 248.04 ? 581 ASP H OD1 1 
ATOM 4994 O OD2 . ASP C 1 272 ? 156.006 200.201 186.311 1.00 248.04 ? 581 ASP H OD2 1 
ATOM 4995 N N   . ARG C 1 273 ? 158.646 203.116 188.346 1.00 243.87 ? 582 ARG H N   1 
ATOM 4996 C CA  . ARG C 1 273 ? 158.117 204.255 189.091 1.00 243.87 ? 582 ARG H CA  1 
ATOM 4997 C C   . ARG C 1 273 ? 159.101 205.418 189.132 1.00 243.87 ? 582 ARG H C   1 
ATOM 4998 O O   . ARG C 1 273 ? 158.681 206.578 189.225 1.00 243.87 ? 582 ARG H O   1 
ATOM 4999 C CB  . ARG C 1 273 ? 157.733 203.832 190.508 1.00 243.87 ? 582 ARG H CB  1 
ATOM 5000 C CG  . ARG C 1 273 ? 156.821 204.824 191.210 1.00 243.87 ? 582 ARG H CG  1 
ATOM 5001 C CD  . ARG C 1 273 ? 155.484 204.945 190.496 1.00 243.87 ? 582 ARG H CD  1 
ATOM 5002 N NE  . ARG C 1 273 ? 154.358 204.950 191.423 1.00 243.87 ? 582 ARG H NE  1 
ATOM 5003 C CZ  . ARG C 1 273 ? 154.356 204.352 192.606 1.00 243.87 ? 582 ARG H CZ  1 
ATOM 5004 N N   . CYS C 1 274 ? 160.403 205.136 189.063 1.00 249.83 ? 583 CYS H N   1 
ATOM 5005 C CA  . CYS C 1 274 ? 161.384 206.217 189.033 1.00 249.83 ? 583 CYS H CA  1 
ATOM 5006 C C   . CYS C 1 274 ? 161.154 207.128 187.835 1.00 249.83 ? 583 CYS H C   1 
ATOM 5007 O O   . CYS C 1 274 ? 161.109 208.355 187.972 1.00 249.83 ? 583 CYS H O   1 
ATOM 5008 C CB  . CYS C 1 274 ? 162.800 205.641 189.014 1.00 249.83 ? 583 CYS H CB  1 
ATOM 5009 S SG  . CYS C 1 274 ? 163.305 204.833 190.551 1.00 249.83 ? 583 CYS H SG  1 
ATOM 5010 N N   . VAL C 1 275 ? 160.985 206.542 186.650 1.00 244.68 ? 584 VAL H N   1 
ATOM 5011 C CA  . VAL C 1 275 ? 160.699 207.344 185.465 1.00 244.68 ? 584 VAL H CA  1 
ATOM 5012 C C   . VAL C 1 275 ? 159.258 207.846 185.488 1.00 244.68 ? 584 VAL H C   1 
ATOM 5013 O O   . VAL C 1 275 ? 158.955 208.913 184.937 1.00 244.68 ? 584 VAL H O   1 
ATOM 5014 C CB  . VAL C 1 275 ? 161.016 206.528 184.199 1.00 244.68 ? 584 VAL H CB  1 
ATOM 5015 C CG1 . VAL C 1 275 ? 160.578 207.266 182.949 1.00 244.68 ? 584 VAL H CG1 1 
ATOM 5016 C CG2 . VAL C 1 275 ? 162.503 206.231 184.141 1.00 244.68 ? 584 VAL H CG2 1 
ATOM 5017 N N   . GLU C 1 276 ? 158.355 207.102 186.131 1.00 243.36 ? 585 GLU H N   1 
ATOM 5018 C CA  . GLU C 1 276 ? 157.001 207.596 186.360 1.00 243.36 ? 585 GLU H CA  1 
ATOM 5019 C C   . GLU C 1 276 ? 157.025 208.964 187.031 1.00 243.36 ? 585 GLU H C   1 
ATOM 5020 O O   . GLU C 1 276 ? 156.302 209.881 186.627 1.00 243.36 ? 585 GLU H O   1 
ATOM 5021 C CB  . GLU C 1 276 ? 156.232 206.604 187.234 1.00 243.36 ? 585 GLU H CB  1 
ATOM 5022 C CG  . GLU C 1 276 ? 155.430 205.518 186.525 1.00 243.36 ? 585 GLU H CG  1 
ATOM 5023 C CD  . GLU C 1 276 ? 154.377 206.057 185.580 1.00 243.36 ? 585 GLU H CD  1 
ATOM 5024 O OE1 . GLU C 1 276 ? 154.315 205.587 184.428 1.00 243.36 ? 585 GLU H OE1 1 
ATOM 5025 O OE2 . GLU C 1 276 ? 153.599 206.942 185.994 1.00 243.36 ? 585 GLU H OE2 1 
ATOM 5026 N N   . VAL C 1 277 ? 157.862 209.115 188.055 1.00 231.28 ? 586 VAL H N   1 
ATOM 5027 C CA  . VAL C 1 277 ? 157.883 210.335 188.853 1.00 231.28 ? 586 VAL H CA  1 
ATOM 5028 C C   . VAL C 1 277 ? 158.916 211.349 188.362 1.00 231.28 ? 586 VAL H C   1 
ATOM 5029 O O   . VAL C 1 277 ? 158.825 212.532 188.725 1.00 231.28 ? 586 VAL H O   1 
ATOM 5030 C CB  . VAL C 1 277 ? 158.124 209.994 190.341 1.00 231.28 ? 586 VAL H CB  1 
ATOM 5031 C CG1 . VAL C 1 277 ? 159.532 209.442 190.547 1.00 231.28 ? 586 VAL H CG1 1 
ATOM 5032 C CG2 . VAL C 1 277 ? 157.834 211.189 191.252 1.00 231.28 ? 586 VAL H CG2 1 
ATOM 5033 N N   . ILE C 1 278 ? 159.885 210.933 187.540 1.00 214.13 ? 587 ILE H N   1 
ATOM 5034 C CA  . ILE C 1 278 ? 160.864 211.887 187.023 1.00 214.13 ? 587 ILE H CA  1 
ATOM 5035 C C   . ILE C 1 278 ? 160.175 212.923 186.143 1.00 214.13 ? 587 ILE H C   1 
ATOM 5036 O O   . ILE C 1 278 ? 160.612 214.077 186.057 1.00 214.13 ? 587 ILE H O   1 
ATOM 5037 C CB  . ILE C 1 278 ? 161.994 211.152 186.273 1.00 214.13 ? 587 ILE H CB  1 
ATOM 5038 C CG1 . ILE C 1 278 ? 163.238 212.032 186.184 1.00 214.13 ? 587 ILE H CG1 1 
ATOM 5039 C CG2 . ILE C 1 278 ? 161.563 210.748 184.876 1.00 214.13 ? 587 ILE H CG2 1 
ATOM 5040 C CD1 . ILE C 1 278 ? 163.942 212.205 187.496 1.00 214.13 ? 587 ILE H CD1 1 
ATOM 5041 N N   . ALA C 1 279 ? 159.078 212.532 185.489 1.00 214.14 ? 588 ALA H N   1 
ATOM 5042 C CA  . ALA C 1 279 ? 158.270 213.454 184.703 1.00 214.14 ? 588 ALA H CA  1 
ATOM 5043 C C   . ALA C 1 279 ? 157.220 214.176 185.535 1.00 214.14 ? 588 ALA H C   1 
ATOM 5044 O O   . ALA C 1 279 ? 156.590 215.112 185.031 1.00 214.14 ? 588 ALA H O   1 
ATOM 5045 C CB  . ALA C 1 279 ? 157.588 212.710 183.553 1.00 214.14 ? 588 ALA H CB  1 
ATOM 5046 N N   . LYS C 1 280 ? 157.009 213.759 186.786 1.00 198.74 ? 589 LYS H N   1 
ATOM 5047 C CA  . LYS C 1 280 ? 156.158 214.520 187.689 1.00 198.74 ? 589 LYS H CA  1 
ATOM 5048 C C   . LYS C 1 280 ? 156.761 215.871 188.039 1.00 198.74 ? 589 LYS H C   1 
ATOM 5049 O O   . LYS C 1 280 ? 156.020 216.846 188.198 1.00 198.74 ? 589 LYS H O   1 
ATOM 5050 C CB  . LYS C 1 280 ? 155.895 213.723 188.969 1.00 198.74 ? 589 LYS H CB  1 
ATOM 5051 C CG  . LYS C 1 280 ? 154.865 214.352 189.890 1.00 198.74 ? 589 LYS H CG  1 
ATOM 5052 C CD  . LYS C 1 280 ? 153.504 214.469 189.231 1.00 198.74 ? 589 LYS H CD  1 
ATOM 5053 C CE  . LYS C 1 280 ? 152.915 213.103 188.927 1.00 198.74 ? 589 LYS H CE  1 
ATOM 5054 N NZ  . LYS C 1 280 ? 152.550 212.385 190.180 1.00 198.74 ? 589 LYS H NZ  1 
ATOM 5055 N N   . GLU C 1 281 ? 158.088 215.954 188.152 1.00 182.41 ? 590 GLU H N   1 
ATOM 5056 C CA  . GLU C 1 281 ? 158.760 217.206 188.461 1.00 182.41 ? 590 GLU H CA  1 
ATOM 5057 C C   . GLU C 1 281 ? 159.756 217.644 187.400 1.00 182.41 ? 590 GLU H C   1 
ATOM 5058 O O   . GLU C 1 281 ? 160.309 218.741 187.525 1.00 182.41 ? 590 GLU H O   1 
ATOM 5059 C CB  . GLU C 1 281 ? 159.515 217.105 189.790 1.00 182.41 ? 590 GLU H CB  1 
ATOM 5060 C CG  . GLU C 1 281 ? 160.422 215.899 189.842 1.00 182.41 ? 590 GLU H CG  1 
ATOM 5061 C CD  . GLU C 1 281 ? 161.310 215.898 191.060 1.00 182.41 ? 590 GLU H CD  1 
ATOM 5062 O OE1 . GLU C 1 281 ? 161.634 216.995 191.558 1.00 182.41 ? 590 GLU H OE1 1 
ATOM 5063 O OE2 . GLU C 1 281 ? 161.716 214.803 191.498 1.00 182.41 ? 590 GLU H OE2 1 
ATOM 5064 N N   . GLY C 1 282 ? 160.033 216.823 186.392 1.00 179.46 ? 591 GLY H N   1 
ATOM 5065 C CA  . GLY C 1 282 ? 161.026 217.187 185.403 1.00 179.46 ? 591 GLY H CA  1 
ATOM 5066 C C   . GLY C 1 282 ? 160.602 218.341 184.521 1.00 179.46 ? 591 GLY H C   1 
ATOM 5067 O O   . GLY C 1 282 ? 159.797 218.167 183.602 1.00 179.46 ? 591 GLY H O   1 
ATOM 5068 N N   . GLN C 1 283 ? 161.152 219.527 184.780 1.00 160.50 ? 592 GLN H N   1 
ATOM 5069 C CA  . GLN C 1 283 ? 160.882 220.692 183.945 1.00 160.50 ? 592 GLN H CA  1 
ATOM 5070 C C   . GLN C 1 283 ? 161.932 220.838 182.849 1.00 160.50 ? 592 GLN H C   1 
ATOM 5071 O O   . GLN C 1 283 ? 161.601 220.866 181.663 1.00 160.50 ? 592 GLN H O   1 
ATOM 5072 C CB  . GLN C 1 283 ? 160.838 221.966 184.796 1.00 160.50 ? 592 GLN H CB  1 
ATOM 5073 C CG  . GLN C 1 283 ? 160.078 221.830 186.095 1.00 160.50 ? 592 GLN H CG  1 
ATOM 5074 C CD  . GLN C 1 283 ? 158.580 221.794 185.887 1.00 160.50 ? 592 GLN H CD  1 
ATOM 5075 O OE1 . GLN C 1 283 ? 157.961 222.808 185.561 1.00 160.50 ? 592 GLN H OE1 1 
ATOM 5076 N NE2 . GLN C 1 283 ? 157.987 220.622 186.072 1.00 160.50 ? 592 GLN H NE2 1 
ATOM 5077 N N   . ASN C 1 284 ? 163.198 220.927 183.239 1.00 138.40 ? 593 ASN H N   1 
ATOM 5078 C CA  . ASN C 1 284 ? 164.297 221.197 182.324 1.00 138.40 ? 593 ASN H CA  1 
ATOM 5079 C C   . ASN C 1 284 ? 164.941 219.939 181.766 1.00 138.40 ? 593 ASN H C   1 
ATOM 5080 O O   . ASN C 1 284 ? 165.853 220.040 180.942 1.00 138.40 ? 593 ASN H O   1 
ATOM 5081 C CB  . ASN C 1 284 ? 165.352 222.037 183.040 1.00 138.40 ? 593 ASN H CB  1 
ATOM 5082 C CG  . ASN C 1 284 ? 165.946 221.314 184.229 1.00 138.40 ? 593 ASN H CG  1 
ATOM 5083 O OD1 . ASN C 1 284 ? 166.802 220.443 184.086 1.00 138.40 ? 593 ASN H OD1 1 
ATOM 5084 N ND2 . ASN C 1 284 ? 165.458 221.646 185.415 1.00 138.40 ? 593 ASN H ND2 1 
ATOM 5085 N N   . LEU C 1 285 ? 164.491 218.764 182.188 1.00 132.10 ? 594 LEU H N   1 
ATOM 5086 C CA  . LEU C 1 285 ? 165.115 217.530 181.736 1.00 132.10 ? 594 LEU H CA  1 
ATOM 5087 C C   . LEU C 1 285 ? 164.825 217.313 180.256 1.00 132.10 ? 594 LEU H C   1 
ATOM 5088 O O   . LEU C 1 285 ? 163.699 217.511 179.795 1.00 132.10 ? 594 LEU H O   1 
ATOM 5089 C CB  . LEU C 1 285 ? 164.604 216.360 182.570 1.00 132.10 ? 594 LEU H CB  1 
ATOM 5090 C CG  . LEU C 1 285 ? 165.500 215.132 182.593 1.00 132.10 ? 594 LEU H CG  1 
ATOM 5091 C CD1 . LEU C 1 285 ? 166.733 215.424 183.429 1.00 132.10 ? 594 LEU H CD1 1 
ATOM 5092 C CD2 . LEU C 1 285 ? 164.732 213.973 183.180 1.00 132.10 ? 594 LEU H CD2 1 
ATOM 5093 N N   . LYS C 1 286 ? 165.850 216.912 179.507 1.00 143.38 ? 595 LYS H N   1 
ATOM 5094 C CA  . LYS C 1 286 ? 165.738 216.825 178.062 1.00 143.38 ? 595 LYS H CA  1 
ATOM 5095 C C   . LYS C 1 286 ? 166.083 215.461 177.489 1.00 143.38 ? 595 LYS H C   1 
ATOM 5096 O O   . LYS C 1 286 ? 165.820 215.229 176.304 1.00 143.38 ? 595 LYS H O   1 
ATOM 5097 C CB  . LYS C 1 286 ? 166.629 217.882 177.396 1.00 143.38 ? 595 LYS H CB  1 
ATOM 5098 C CG  . LYS C 1 286 ? 166.266 219.287 177.788 1.00 143.38 ? 595 LYS H CG  1 
ATOM 5099 C CD  . LYS C 1 286 ? 164.892 219.646 177.278 1.00 143.38 ? 595 LYS H CD  1 
ATOM 5100 C CE  . LYS C 1 286 ? 164.596 221.108 177.527 1.00 143.38 ? 595 LYS H CE  1 
ATOM 5101 N NZ  . LYS C 1 286 ? 164.437 221.369 178.984 1.00 143.38 ? 595 LYS H NZ  1 
ATOM 5102 N N   . GLU C 1 287 ? 166.655 214.556 178.278 1.00 135.74 ? 596 GLU H N   1 
ATOM 5103 C CA  . GLU C 1 287 ? 167.027 213.253 177.752 1.00 135.74 ? 596 GLU H CA  1 
ATOM 5104 C C   . GLU C 1 287 ? 167.201 212.243 178.878 1.00 135.74 ? 596 GLU H C   1 
ATOM 5105 O O   . GLU C 1 287 ? 167.821 212.526 179.906 1.00 135.74 ? 596 GLU H O   1 
ATOM 5106 C CB  . GLU C 1 287 ? 168.291 213.361 176.897 1.00 135.74 ? 596 GLU H CB  1 
ATOM 5107 C CG  . GLU C 1 287 ? 169.510 213.822 177.649 1.00 135.74 ? 596 GLU H CG  1 
ATOM 5108 C CD  . GLU C 1 287 ? 169.856 215.253 177.297 1.00 135.74 ? 596 GLU H CD  1 
ATOM 5109 O OE1 . GLU C 1 287 ? 168.947 215.979 176.856 1.00 135.74 ? 596 GLU H OE1 1 
ATOM 5110 O OE2 . GLU C 1 287 ? 171.029 215.654 177.427 1.00 135.74 ? 596 GLU H OE2 1 
ATOM 5111 N N   . LEU C 1 288 ? 166.642 211.057 178.651 1.00 143.23 ? 597 LEU H N   1 
ATOM 5112 C CA  . LEU C 1 288 ? 166.725 209.918 179.551 1.00 143.23 ? 597 LEU H CA  1 
ATOM 5113 C C   . LEU C 1 288 ? 167.343 208.763 178.784 1.00 143.23 ? 597 LEU H C   1 
ATOM 5114 O O   . LEU C 1 288 ? 167.041 208.567 177.605 1.00 143.23 ? 597 LEU H O   1 
ATOM 5115 C CB  . LEU C 1 288 ? 165.348 209.497 180.066 1.00 143.23 ? 597 LEU H CB  1 
ATOM 5116 C CG  . LEU C 1 288 ? 164.640 210.293 181.157 1.00 143.23 ? 597 LEU H CG  1 
ATOM 5117 C CD1 . LEU C 1 288 ? 164.113 211.598 180.605 1.00 143.23 ? 597 LEU H CD1 1 
ATOM 5118 C CD2 . LEU C 1 288 ? 163.511 209.468 181.754 1.00 143.23 ? 597 LEU H CD2 1 
ATOM 5119 N N   . TYR C 1 289 ? 168.191 207.990 179.448 1.00 138.98 ? 598 TYR H N   1 
ATOM 5120 C CA  . TYR C 1 289 ? 168.972 206.965 178.766 1.00 138.98 ? 598 TYR H CA  1 
ATOM 5121 C C   . TYR C 1 289 ? 168.648 205.618 179.405 1.00 138.98 ? 598 TYR H C   1 
ATOM 5122 O O   . TYR C 1 289 ? 169.460 205.033 180.125 1.00 138.98 ? 598 TYR H O   1 
ATOM 5123 C CB  . TYR C 1 289 ? 170.441 207.319 178.844 1.00 138.98 ? 598 TYR H CB  1 
ATOM 5124 C CG  . TYR C 1 289 ? 170.739 208.668 178.233 1.00 138.98 ? 598 TYR H CG  1 
ATOM 5125 C CD1 . TYR C 1 289 ? 170.117 209.074 177.063 1.00 138.98 ? 598 TYR H CD1 1 
ATOM 5126 C CD2 . TYR C 1 289 ? 171.612 209.551 178.841 1.00 138.98 ? 598 TYR H CD2 1 
ATOM 5127 C CE1 . TYR C 1 289 ? 170.380 210.316 176.504 1.00 138.98 ? 598 TYR H CE1 1 
ATOM 5128 C CE2 . TYR C 1 289 ? 171.882 210.795 178.295 1.00 138.98 ? 598 TYR H CE2 1 
ATOM 5129 C CZ  . TYR C 1 289 ? 171.267 211.167 177.123 1.00 138.98 ? 598 TYR H CZ  1 
ATOM 5130 N N   . LEU C 1 290 ? 167.467 205.098 179.087 1.00 154.87 ? 599 LEU H N   1 
ATOM 5131 C CA  . LEU C 1 290 ? 166.950 203.875 179.686 1.00 154.87 ? 599 LEU H CA  1 
ATOM 5132 C C   . LEU C 1 290 ? 167.343 202.714 178.788 1.00 154.87 ? 599 LEU H C   1 
ATOM 5133 O O   . LEU C 1 290 ? 166.822 202.579 177.678 1.00 154.87 ? 599 LEU H O   1 
ATOM 5134 C CB  . LEU C 1 290 ? 165.433 203.940 179.847 1.00 154.87 ? 599 LEU H CB  1 
ATOM 5135 C CG  . LEU C 1 290 ? 164.821 204.672 181.040 1.00 154.87 ? 599 LEU H CG  1 
ATOM 5136 C CD1 . LEU C 1 290 ? 165.108 206.154 180.977 1.00 154.87 ? 599 LEU H CD1 1 
ATOM 5137 C CD2 . LEU C 1 290 ? 163.326 204.426 181.079 1.00 154.87 ? 599 LEU H CD2 1 
ATOM 5138 N N   . VAL C 1 291 ? 168.261 201.880 179.262 1.00 149.93 ? 600 VAL H N   1 
ATOM 5139 C CA  . VAL C 1 291 ? 168.762 200.750 178.490 1.00 149.93 ? 600 VAL H CA  1 
ATOM 5140 C C   . VAL C 1 291 ? 168.882 199.545 179.409 1.00 149.93 ? 600 VAL H C   1 
ATOM 5141 O O   . VAL C 1 291 ? 169.344 199.670 180.548 1.00 149.93 ? 600 VAL H O   1 
ATOM 5142 C CB  . VAL C 1 291 ? 170.112 201.071 177.828 1.00 149.93 ? 600 VAL H CB  1 
ATOM 5143 C CG1 . VAL C 1 291 ? 169.928 202.124 176.761 1.00 149.93 ? 600 VAL H CG1 1 
ATOM 5144 C CG2 . VAL C 1 291 ? 171.064 201.576 178.853 1.00 149.93 ? 600 VAL H CG2 1 
ATOM 5145 N N   . SER C 1 292 ? 168.453 198.384 178.917 1.00 152.26 ? 601 SER H N   1 
ATOM 5146 C CA  . SER C 1 292 ? 168.455 197.143 179.683 1.00 152.26 ? 601 SER H CA  1 
ATOM 5147 C C   . SER C 1 292 ? 167.673 197.273 180.984 1.00 152.26 ? 601 SER H C   1 
ATOM 5148 O O   . SER C 1 292 ? 167.882 196.495 181.918 1.00 152.26 ? 601 SER H O   1 
ATOM 5149 C CB  . SER C 1 292 ? 169.883 196.665 179.965 1.00 152.26 ? 601 SER H CB  1 
ATOM 5150 O OG  . SER C 1 292 ? 170.403 197.285 181.129 1.00 152.26 ? 601 SER H OG  1 
ATOM 5151 N N   . CYS C 1 293 ? 166.779 198.252 181.064 1.00 155.27 ? 602 CYS H N   1 
ATOM 5152 C CA  . CYS C 1 293 ? 166.002 198.487 182.267 1.00 155.27 ? 602 CYS H CA  1 
ATOM 5153 C C   . CYS C 1 293 ? 164.814 197.540 182.325 1.00 155.27 ? 602 CYS H C   1 
ATOM 5154 O O   . CYS C 1 293 ? 164.121 197.316 181.330 1.00 155.27 ? 602 CYS H O   1 
ATOM 5155 C CB  . CYS C 1 293 ? 165.519 199.935 182.320 1.00 155.27 ? 602 CYS H CB  1 
ATOM 5156 S SG  . CYS C 1 293 ? 164.659 200.481 180.832 1.00 155.27 ? 602 CYS H SG  1 
ATOM 5157 N N   . LYS C 1 294 ? 164.579 196.991 183.512 1.00 164.92 ? 603 LYS H N   1 
ATOM 5158 C CA  . LYS C 1 294 ? 163.469 196.072 183.714 1.00 164.92 ? 603 LYS H CA  1 
ATOM 5159 C C   . LYS C 1 294 ? 162.174 196.844 183.932 1.00 164.92 ? 603 LYS H C   1 
ATOM 5160 O O   . LYS C 1 294 ? 161.507 196.685 184.959 1.00 164.92 ? 603 LYS H O   1 
ATOM 5161 C CB  . LYS C 1 294 ? 163.757 195.142 184.890 1.00 164.92 ? 603 LYS H CB  1 
ATOM 5162 C CG  . LYS C 1 294 ? 165.095 194.433 184.782 1.00 164.92 ? 603 LYS H CG  1 
ATOM 5163 C CD  . LYS C 1 294 ? 165.275 193.813 183.407 1.00 164.92 ? 603 LYS H CD  1 
ATOM 5164 C CE  . LYS C 1 294 ? 166.733 193.785 183.010 1.00 164.92 ? 603 LYS H CE  1 
ATOM 5165 N NZ  . LYS C 1 294 ? 166.898 193.480 181.567 1.00 164.92 ? 603 LYS H NZ  1 
ATOM 5166 N N   . ILE C 1 295 ? 161.824 197.688 182.962 1.00 184.80 ? 604 ILE H N   1 
ATOM 5167 C CA  . ILE C 1 295 ? 160.598 198.467 183.041 1.00 184.80 ? 604 ILE H CA  1 
ATOM 5168 C C   . ILE C 1 295 ? 159.423 197.629 182.554 1.00 184.80 ? 604 ILE H C   1 
ATOM 5169 O O   . ILE C 1 295 ? 159.593 196.598 181.891 1.00 184.80 ? 604 ILE H O   1 
ATOM 5170 C CB  . ILE C 1 295 ? 160.729 199.751 182.208 1.00 184.80 ? 604 ILE H CB  1 
ATOM 5171 C CG1 . ILE C 1 295 ? 161.166 199.391 180.789 1.00 184.80 ? 604 ILE H CG1 1 
ATOM 5172 C CG2 . ILE C 1 295 ? 161.719 200.696 182.851 1.00 184.80 ? 604 ILE H CG2 1 
ATOM 5173 C CD1 . ILE C 1 295 ? 161.148 200.551 179.837 1.00 184.80 ? 604 ILE H CD1 1 
ATOM 5174 N N   . THR C 1 296 ? 158.216 198.087 182.875 1.00 211.51 ? 605 THR H N   1 
ATOM 5175 C CA  . THR C 1 296 ? 156.983 197.480 182.381 1.00 211.51 ? 605 THR H CA  1 
ATOM 5176 C C   . THR C 1 296 ? 156.514 198.165 181.109 1.00 211.51 ? 605 THR H C   1 
ATOM 5177 O O   . THR C 1 296 ? 155.408 197.913 180.622 1.00 211.51 ? 605 THR H O   1 
ATOM 5178 C CB  . THR C 1 296 ? 155.897 197.531 183.449 1.00 211.51 ? 605 THR H CB  1 
ATOM 5179 O OG1 . THR C 1 296 ? 155.578 198.897 183.739 1.00 211.51 ? 605 THR H OG1 1 
ATOM 5180 C CG2 . THR C 1 296 ? 156.382 196.859 184.724 1.00 211.51 ? 605 THR H CG2 1 
ATOM 5181 N N   . ASP C 1 297 ? 157.357 199.044 180.565 1.00 198.68 ? 606 ASP H N   1 
ATOM 5182 C CA  . ASP C 1 297 ? 157.101 199.765 179.325 1.00 198.68 ? 606 ASP H CA  1 
ATOM 5183 C C   . ASP C 1 297 ? 155.795 200.543 179.454 1.00 198.68 ? 606 ASP H C   1 
ATOM 5184 O O   . ASP C 1 297 ? 155.028 200.666 178.494 1.00 198.68 ? 606 ASP H O   1 
ATOM 5185 C CB  . ASP C 1 297 ? 157.074 198.781 178.146 1.00 198.68 ? 606 ASP H CB  1 
ATOM 5186 C CG  . ASP C 1 297 ? 157.031 199.471 176.787 1.00 198.68 ? 606 ASP H CG  1 
ATOM 5187 O OD1 . ASP C 1 297 ? 156.989 200.717 176.732 1.00 198.68 ? 606 ASP H OD1 1 
ATOM 5188 O OD2 . ASP C 1 297 ? 157.056 198.754 175.764 1.00 198.68 ? 606 ASP H OD2 1 
ATOM 5189 N N   . TYR C 1 298 ? 155.533 201.071 180.653 1.00 209.59 ? 607 TYR H N   1 
ATOM 5190 C CA  . TYR C 1 298 ? 154.344 201.872 180.907 1.00 209.59 ? 607 TYR H CA  1 
ATOM 5191 C C   . TYR C 1 298 ? 154.649 203.304 181.311 1.00 209.59 ? 607 TYR H C   1 
ATOM 5192 O O   . TYR C 1 298 ? 153.772 204.162 181.185 1.00 209.59 ? 607 TYR H O   1 
ATOM 5193 C CB  . TYR C 1 298 ? 153.481 201.226 182.003 1.00 209.59 ? 607 TYR H CB  1 
ATOM 5194 C CG  . TYR C 1 298 ? 152.157 201.922 182.221 1.00 209.59 ? 607 TYR H CG  1 
ATOM 5195 C CD1 . TYR C 1 298 ? 151.155 201.871 181.261 1.00 209.59 ? 607 TYR H CD1 1 
ATOM 5196 C CD2 . TYR C 1 298 ? 151.914 202.638 183.385 1.00 209.59 ? 607 TYR H CD2 1 
ATOM 5197 C CE1 . TYR C 1 298 ? 149.945 202.510 181.457 1.00 209.59 ? 607 TYR H CE1 1 
ATOM 5198 C CE2 . TYR C 1 298 ? 150.706 203.280 183.591 1.00 209.59 ? 607 TYR H CE2 1 
ATOM 5199 C CZ  . TYR C 1 298 ? 149.725 203.212 182.623 1.00 209.59 ? 607 TYR H CZ  1 
ATOM 5200 N N   . ALA C 1 299 ? 155.866 203.591 181.765 1.00 221.00 ? 608 ALA H N   1 
ATOM 5201 C CA  . ALA C 1 299 ? 156.218 204.959 182.111 1.00 221.00 ? 608 ALA H CA  1 
ATOM 5202 C C   . ALA C 1 299 ? 156.243 205.875 180.899 1.00 221.00 ? 608 ALA H C   1 
ATOM 5203 O O   . ALA C 1 299 ? 156.290 207.099 181.064 1.00 221.00 ? 608 ALA H O   1 
ATOM 5204 C CB  . ALA C 1 299 ? 157.578 204.999 182.814 1.00 221.00 ? 608 ALA H CB  1 
ATOM 5205 N N   . LEU C 1 300 ? 156.215 205.312 179.694 1.00 231.96 ? 609 LEU H N   1 
ATOM 5206 C CA  . LEU C 1 300 ? 156.303 206.128 178.492 1.00 231.96 ? 609 LEU H CA  1 
ATOM 5207 C C   . LEU C 1 300 ? 155.073 207.012 178.333 1.00 231.96 ? 609 LEU H C   1 
ATOM 5208 O O   . LEU C 1 300 ? 155.186 208.193 177.996 1.00 231.96 ? 609 LEU H O   1 
ATOM 5209 C CB  . LEU C 1 300 ? 156.494 205.234 177.270 1.00 231.96 ? 609 LEU H CB  1 
ATOM 5210 C CG  . LEU C 1 300 ? 157.950 204.913 176.925 1.00 231.96 ? 609 LEU H CG  1 
ATOM 5211 C CD1 . LEU C 1 300 ? 158.708 206.189 176.602 1.00 231.96 ? 609 LEU H CD1 1 
ATOM 5212 C CD2 . LEU C 1 300 ? 158.647 204.134 178.037 1.00 231.96 ? 609 LEU H CD2 1 
ATOM 5213 N N   . ILE C 1 301 ? 153.883 206.458 178.562 1.00 222.77 ? 610 ILE H N   1 
ATOM 5214 C CA  . ILE C 1 301 ? 152.680 207.277 178.450 1.00 222.77 ? 610 ILE H CA  1 
ATOM 5215 C C   . ILE C 1 301 ? 152.667 208.338 179.539 1.00 222.77 ? 610 ILE H C   1 
ATOM 5216 O O   . ILE C 1 301 ? 152.228 209.474 179.319 1.00 222.77 ? 610 ILE H O   1 
ATOM 5217 C CB  . ILE C 1 301 ? 151.414 206.400 178.482 1.00 222.77 ? 610 ILE H CB  1 
ATOM 5218 C CG1 . ILE C 1 301 ? 150.171 207.259 178.240 1.00 222.77 ? 610 ILE H CG1 1 
ATOM 5219 C CG2 . ILE C 1 301 ? 151.305 205.641 179.795 1.00 222.77 ? 610 ILE H CG2 1 
ATOM 5220 C CD1 . ILE C 1 301 ? 150.246 208.104 176.990 1.00 222.77 ? 610 ILE H CD1 1 
ATOM 5221 N N   . ALA C 1 302 ? 153.175 207.997 180.724 1.00 224.76 ? 611 ALA H N   1 
ATOM 5222 C CA  . ALA C 1 302 ? 153.233 208.971 181.805 1.00 224.76 ? 611 ALA H CA  1 
ATOM 5223 C C   . ALA C 1 302 ? 154.174 210.118 181.466 1.00 224.76 ? 611 ALA H C   1 
ATOM 5224 O O   . ALA C 1 302 ? 153.881 211.276 181.772 1.00 224.76 ? 611 ALA H O   1 
ATOM 5225 C CB  . ALA C 1 302 ? 153.663 208.295 183.100 1.00 224.76 ? 611 ALA H CB  1 
ATOM 5226 N N   . ILE C 1 303 ? 155.317 209.819 180.850 1.00 228.02 ? 612 ILE H N   1 
ATOM 5227 C CA  . ILE C 1 303 ? 156.236 210.899 180.511 1.00 228.02 ? 612 ILE H CA  1 
ATOM 5228 C C   . ILE C 1 303 ? 155.748 211.666 179.288 1.00 228.02 ? 612 ILE H C   1 
ATOM 5229 O O   . ILE C 1 303 ? 156.078 212.845 179.121 1.00 228.02 ? 612 ILE H O   1 
ATOM 5230 C CB  . ILE C 1 303 ? 157.665 210.365 180.310 1.00 228.02 ? 612 ILE H CB  1 
ATOM 5231 C CG1 . ILE C 1 303 ? 157.724 209.380 179.151 1.00 228.02 ? 612 ILE H CG1 1 
ATOM 5232 C CG2 . ILE C 1 303 ? 158.165 209.700 181.577 1.00 228.02 ? 612 ILE H CG2 1 
ATOM 5233 C CD1 . ILE C 1 303 ? 159.121 209.002 178.762 1.00 228.02 ? 612 ILE H CD1 1 
ATOM 5234 N N   . GLY C 1 304 ? 154.964 211.026 178.417 1.00 249.40 ? 613 GLY H N   1 
ATOM 5235 C CA  . GLY C 1 304 ? 154.359 211.735 177.305 1.00 249.40 ? 613 GLY H CA  1 
ATOM 5236 C C   . GLY C 1 304 ? 153.182 212.600 177.694 1.00 249.40 ? 613 GLY H C   1 
ATOM 5237 O O   . GLY C 1 304 ? 152.831 213.522 176.952 1.00 249.40 ? 613 GLY H O   1 
ATOM 5238 N N   . ARG C 1 305 ? 152.559 212.311 178.834 1.00 265.87 ? 614 ARG H N   1 
ATOM 5239 C CA  . ARG C 1 305 ? 151.461 213.124 179.340 1.00 265.87 ? 614 ARG H CA  1 
ATOM 5240 C C   . ARG C 1 305 ? 151.960 214.221 180.276 1.00 265.87 ? 614 ARG H C   1 
ATOM 5241 O O   . ARG C 1 305 ? 151.598 215.393 180.125 1.00 265.87 ? 614 ARG H O   1 
ATOM 5242 C CB  . ARG C 1 305 ? 150.448 212.234 180.068 1.00 265.87 ? 614 ARG H CB  1 
ATOM 5243 C CG  . ARG C 1 305 ? 149.433 211.569 179.167 1.00 265.87 ? 614 ARG H CG  1 
ATOM 5244 C CD  . ARG C 1 305 ? 148.334 210.923 179.985 1.00 265.87 ? 614 ARG H CD  1 
ATOM 5245 N NE  . ARG C 1 305 ? 147.426 210.151 179.148 1.00 265.87 ? 614 ARG H NE  1 
ATOM 5246 C CZ  . ARG C 1 305 ? 146.564 210.683 178.292 1.00 265.87 ? 614 ARG H CZ  1 
ATOM 5247 N N   . TYR C 1 306 ? 152.794 213.852 181.244 1.00 257.68 ? 615 TYR H N   1 
ATOM 5248 C CA  . TYR C 1 306 ? 153.130 214.703 182.375 1.00 257.68 ? 615 TYR H CA  1 
ATOM 5249 C C   . TYR C 1 306 ? 154.414 215.499 182.186 1.00 257.68 ? 615 TYR H C   1 
ATOM 5250 O O   . TYR C 1 306 ? 154.820 216.211 183.110 1.00 257.68 ? 615 TYR H O   1 
ATOM 5251 C CB  . TYR C 1 306 ? 153.230 213.850 183.642 1.00 257.68 ? 615 TYR H CB  1 
ATOM 5252 C CG  . TYR C 1 306 ? 151.881 213.533 184.247 1.00 257.68 ? 615 TYR H CG  1 
ATOM 5253 C CD1 . TYR C 1 306 ? 151.039 214.546 184.682 1.00 257.68 ? 615 TYR H CD1 1 
ATOM 5254 C CD2 . TYR C 1 306 ? 151.442 212.221 184.368 1.00 257.68 ? 615 TYR H CD2 1 
ATOM 5255 C CE1 . TYR C 1 306 ? 149.804 214.264 185.230 1.00 257.68 ? 615 TYR H CE1 1 
ATOM 5256 C CE2 . TYR C 1 306 ? 150.207 211.930 184.916 1.00 257.68 ? 615 TYR H CE2 1 
ATOM 5257 C CZ  . TYR C 1 306 ? 149.394 212.954 185.344 1.00 257.68 ? 615 TYR H CZ  1 
ATOM 5258 N N   . SER C 1 307 ? 155.067 215.401 181.030 1.00 239.32 ? 616 SER H N   1 
ATOM 5259 C CA  . SER C 1 307 ? 156.239 216.216 180.733 1.00 239.32 ? 616 SER H CA  1 
ATOM 5260 C C   . SER C 1 307 ? 155.972 217.024 179.473 1.00 239.32 ? 616 SER H C   1 
ATOM 5261 O O   . SER C 1 307 ? 155.514 216.475 178.466 1.00 239.32 ? 616 SER H O   1 
ATOM 5262 C CB  . SER C 1 307 ? 157.500 215.364 180.556 1.00 239.32 ? 616 SER H CB  1 
ATOM 5263 O OG  . SER C 1 307 ? 158.614 216.179 180.231 1.00 239.32 ? 616 SER H OG  1 
ATOM 5264 N N   . MET C 1 308 ? 156.265 218.322 179.531 1.00 216.56 ? 617 MET H N   1 
ATOM 5265 C CA  . MET C 1 308 ? 155.997 219.222 178.423 1.00 216.56 ? 617 MET H CA  1 
ATOM 5266 C C   . MET C 1 308 ? 157.245 219.858 177.829 1.00 216.56 ? 617 MET H C   1 
ATOM 5267 O O   . MET C 1 308 ? 157.138 220.545 176.809 1.00 216.56 ? 617 MET H O   1 
ATOM 5268 C CB  . MET C 1 308 ? 155.017 220.325 178.860 1.00 216.56 ? 617 MET H CB  1 
ATOM 5269 C CG  . MET C 1 308 ? 155.649 221.477 179.618 1.00 216.56 ? 617 MET H CG  1 
ATOM 5270 S SD  . MET C 1 308 ? 156.578 220.927 181.062 1.00 216.56 ? 617 MET H SD  1 
ATOM 5271 C CE  . MET C 1 308 ? 155.244 220.456 182.158 1.00 216.56 ? 617 MET H CE  1 
ATOM 5272 N N   . THR C 1 309 ? 158.415 219.666 178.436 1.00 188.05 ? 618 THR H N   1 
ATOM 5273 C CA  . THR C 1 309 ? 159.680 220.160 177.889 1.00 188.05 ? 618 THR H CA  1 
ATOM 5274 C C   . THR C 1 309 ? 160.686 219.015 177.879 1.00 188.05 ? 618 THR H C   1 
ATOM 5275 O O   . THR C 1 309 ? 161.406 218.798 178.856 1.00 188.05 ? 618 THR H O   1 
ATOM 5276 C CB  . THR C 1 309 ? 160.212 221.333 178.675 1.00 188.05 ? 618 THR H CB  1 
ATOM 5277 O OG1 . THR C 1 309 ? 160.852 220.846 179.856 1.00 188.05 ? 618 THR H OG1 1 
ATOM 5278 C CG2 . THR C 1 309 ? 159.100 222.293 179.059 1.00 188.05 ? 618 THR H CG2 1 
ATOM 5279 N N   . ILE C 1 310 ? 160.731 218.287 176.766 1.00 179.79 ? 619 ILE H N   1 
ATOM 5280 C CA  . ILE C 1 310 ? 161.744 217.266 176.516 1.00 179.79 ? 619 ILE H CA  1 
ATOM 5281 C C   . ILE C 1 310 ? 161.659 216.864 175.049 1.00 179.79 ? 619 ILE H C   1 
ATOM 5282 O O   . ILE C 1 310 ? 160.601 216.990 174.423 1.00 179.79 ? 619 ILE H O   1 
ATOM 5283 C CB  . ILE C 1 310 ? 161.578 216.058 177.458 1.00 179.79 ? 619 ILE H CB  1 
ATOM 5284 C CG1 . ILE C 1 310 ? 162.781 215.123 177.357 1.00 179.79 ? 619 ILE H CG1 1 
ATOM 5285 C CG2 . ILE C 1 310 ? 160.289 215.325 177.182 1.00 179.79 ? 619 ILE H CG2 1 
ATOM 5286 C CD1 . ILE C 1 310 ? 162.852 214.105 178.455 1.00 179.79 ? 619 ILE H CD1 1 
ATOM 5287 N N   . GLU C 1 311 ? 162.776 216.416 174.477 1.00 176.71 ? 620 GLU H N   1 
ATOM 5288 C CA  . GLU C 1 311 ? 162.803 216.023 173.076 1.00 176.71 ? 620 GLU H CA  1 
ATOM 5289 C C   . GLU C 1 311 ? 163.373 214.637 172.832 1.00 176.71 ? 620 GLU H C   1 
ATOM 5290 O O   . GLU C 1 311 ? 163.066 214.043 171.792 1.00 176.71 ? 620 GLU H O   1 
ATOM 5291 C CB  . GLU C 1 311 ? 163.611 217.034 172.250 1.00 176.71 ? 620 GLU H CB  1 
ATOM 5292 C CG  . GLU C 1 311 ? 165.073 217.106 172.642 1.00 176.71 ? 620 GLU H CG  1 
ATOM 5293 C CD  . GLU C 1 311 ? 165.341 218.162 173.691 1.00 176.71 ? 620 GLU H CD  1 
ATOM 5294 O OE1 . GLU C 1 311 ? 164.370 218.790 174.162 1.00 176.71 ? 620 GLU H OE1 1 
ATOM 5295 O OE2 . GLU C 1 311 ? 166.519 218.359 174.052 1.00 176.71 ? 620 GLU H OE2 1 
ATOM 5296 N N   . THR C 1 312 ? 164.173 214.098 173.745 1.00 174.40 ? 621 THR H N   1 
ATOM 5297 C CA  . THR C 1 312 ? 164.814 212.809 173.546 1.00 174.40 ? 621 THR H CA  1 
ATOM 5298 C C   . THR C 1 312 ? 164.461 211.893 174.703 1.00 174.40 ? 621 THR H C   1 
ATOM 5299 O O   . THR C 1 312 ? 164.594 212.278 175.868 1.00 174.40 ? 621 THR H O   1 
ATOM 5300 C CB  . THR C 1 312 ? 166.338 212.955 173.442 1.00 174.40 ? 621 THR H CB  1 
ATOM 5301 O OG1 . THR C 1 312 ? 166.659 214.000 172.518 1.00 174.40 ? 621 THR H OG1 1 
ATOM 5302 C CG2 . THR C 1 312 ? 166.969 211.659 172.970 1.00 174.40 ? 621 THR H CG2 1 
ATOM 5303 N N   . VAL C 1 313 ? 164.009 210.689 174.375 1.00 163.79 ? 622 VAL H N   1 
ATOM 5304 C CA  . VAL C 1 313 ? 163.844 209.616 175.351 1.00 163.79 ? 622 VAL H CA  1 
ATOM 5305 C C   . VAL C 1 313 ? 164.349 208.334 174.710 1.00 163.79 ? 622 VAL H C   1 
ATOM 5306 O O   . VAL C 1 313 ? 163.892 207.938 173.634 1.00 163.79 ? 622 VAL H O   1 
ATOM 5307 C CB  . VAL C 1 313 ? 162.388 209.483 175.846 1.00 163.79 ? 622 VAL H CB  1 
ATOM 5308 C CG1 . VAL C 1 313 ? 161.434 209.171 174.705 1.00 163.79 ? 622 VAL H CG1 1 
ATOM 5309 C CG2 . VAL C 1 313 ? 162.306 208.395 176.896 1.00 163.79 ? 622 VAL H CG2 1 
ATOM 5310 N N   . ASP C 1 314 ? 165.325 207.709 175.350 1.00 162.81 ? 623 ASP H N   1 
ATOM 5311 C CA  . ASP C 1 314 ? 166.041 206.591 174.759 1.00 162.81 ? 623 ASP H CA  1 
ATOM 5312 C C   . ASP C 1 314 ? 165.683 205.312 175.498 1.00 162.81 ? 623 ASP H C   1 
ATOM 5313 O O   . ASP C 1 314 ? 166.132 205.093 176.627 1.00 162.81 ? 623 ASP H O   1 
ATOM 5314 C CB  . ASP C 1 314 ? 167.549 206.842 174.783 1.00 162.81 ? 623 ASP H CB  1 
ATOM 5315 C CG  . ASP C 1 314 ? 167.949 208.052 173.953 1.00 162.81 ? 623 ASP H CG  1 
ATOM 5316 O OD1 . ASP C 1 314 ? 167.129 208.497 173.125 1.00 162.81 ? 623 ASP H OD1 1 
ATOM 5317 O OD2 . ASP C 1 314 ? 169.079 208.556 174.124 1.00 162.81 ? 623 ASP H OD2 1 
ATOM 5318 N N   . VAL C 1 315 ? 164.885 204.472 174.849 1.00 163.81 ? 624 VAL H N   1 
ATOM 5319 C CA  . VAL C 1 315 ? 164.563 203.136 175.326 1.00 163.81 ? 624 VAL H CA  1 
ATOM 5320 C C   . VAL C 1 315 ? 165.315 202.185 174.404 1.00 163.81 ? 624 VAL H C   1 
ATOM 5321 O O   . VAL C 1 315 ? 164.869 201.906 173.284 1.00 163.81 ? 624 VAL H O   1 
ATOM 5322 C CB  . VAL C 1 315 ? 163.055 202.862 175.315 1.00 163.81 ? 624 VAL H CB  1 
ATOM 5323 C CG1 . VAL C 1 315 ? 162.769 201.440 175.761 1.00 163.81 ? 624 VAL H CG1 1 
ATOM 5324 C CG2 . VAL C 1 315 ? 162.328 203.865 176.193 1.00 163.81 ? 624 VAL H CG2 1 
ATOM 5325 N N   . GLY C 1 316 ? 166.454 201.679 174.867 1.00 148.19 ? 625 GLY H N   1 
ATOM 5326 C CA  . GLY C 1 316 ? 167.357 200.937 174.011 1.00 148.19 ? 625 GLY H CA  1 
ATOM 5327 C C   . GLY C 1 316 ? 167.196 199.437 174.124 1.00 148.19 ? 625 GLY H C   1 
ATOM 5328 O O   . GLY C 1 316 ? 166.325 198.846 173.482 1.00 148.19 ? 625 GLY H O   1 
ATOM 5329 N N   . TRP C 1 317 ? 168.039 198.808 174.937 1.00 117.08 ? 626 TRP H N   1 
ATOM 5330 C CA  . TRP C 1 317 ? 168.008 197.361 175.094 1.00 117.08 ? 626 TRP H CA  1 
ATOM 5331 C C   . TRP C 1 317 ? 166.844 196.902 175.960 1.00 117.08 ? 626 TRP H C   1 
ATOM 5332 O O   . TRP C 1 317 ? 167.047 196.260 176.993 1.00 117.08 ? 626 TRP H O   1 
ATOM 5333 C CB  . TRP C 1 317 ? 169.316 196.869 175.707 1.00 117.08 ? 626 TRP H CB  1 
ATOM 5334 C CG  . TRP C 1 317 ? 169.787 195.594 175.126 1.00 117.08 ? 626 TRP H CG  1 
ATOM 5335 C CD1 . TRP C 1 317 ? 169.021 194.514 174.821 1.00 117.08 ? 626 TRP H CD1 1 
ATOM 5336 C CD2 . TRP C 1 317 ? 171.139 195.260 174.807 1.00 117.08 ? 626 TRP H CD2 1 
ATOM 5337 N NE1 . TRP C 1 317 ? 169.793 193.510 174.313 1.00 117.08 ? 626 TRP H NE1 1 
ATOM 5338 C CE2 . TRP C 1 317 ? 171.101 193.914 174.284 1.00 117.08 ? 626 TRP H CE2 1 
ATOM 5339 C CE3 . TRP C 1 317 ? 172.355 195.989 174.921 1.00 117.08 ? 626 TRP H CE3 1 
ATOM 5340 C CZ2 . TRP C 1 317 ? 172.217 193.197 173.842 1.00 117.08 ? 626 TRP H CZ2 1 
ATOM 5341 C CZ3 . TRP C 1 317 ? 173.577 195.492 174.540 1.00 117.08 ? 626 TRP H CZ3 1 
ATOM 5342 N N   . CYS C 1 318 ? 165.624 197.208 175.545 1.00 165.16 ? 627 CYS H N   1 
ATOM 5343 C CA  . CYS C 1 318 ? 164.434 196.710 176.212 1.00 165.16 ? 627 CYS H CA  1 
ATOM 5344 C C   . CYS C 1 318 ? 163.860 195.572 175.384 1.00 165.16 ? 627 CYS H C   1 
ATOM 5345 O O   . CYS C 1 318 ? 163.742 195.689 174.160 1.00 165.16 ? 627 CYS H O   1 
ATOM 5346 C CB  . CYS C 1 318 ? 163.397 197.817 176.399 1.00 165.16 ? 627 CYS H CB  1 
ATOM 5347 S SG  . CYS C 1 318 ? 163.644 198.787 177.897 1.00 165.16 ? 627 CYS H SG  1 
ATOM 5348 N N   . LYS C 1 319 ? 163.516 194.473 176.048 1.00 185.26 ? 628 LYS H N   1 
ATOM 5349 C CA  . LYS C 1 319 ? 163.034 193.291 175.346 1.00 185.26 ? 628 LYS H CA  1 
ATOM 5350 C C   . LYS C 1 319 ? 161.656 193.487 174.732 1.00 185.26 ? 628 LYS H C   1 
ATOM 5351 O O   . LYS C 1 319 ? 161.207 192.623 173.972 1.00 185.26 ? 628 LYS H O   1 
ATOM 5352 C CB  . LYS C 1 319 ? 163.032 192.098 176.300 1.00 185.26 ? 628 LYS H CB  1 
ATOM 5353 C CG  . LYS C 1 319 ? 164.319 191.289 176.254 1.00 185.26 ? 628 LYS H CG  1 
ATOM 5354 C CD  . LYS C 1 319 ? 165.479 192.100 176.801 1.00 185.26 ? 628 LYS H CD  1 
ATOM 5355 C CE  . LYS C 1 319 ? 165.199 192.605 178.200 1.00 185.26 ? 628 LYS H CE  1 
ATOM 5356 N NZ  . LYS C 1 319 ? 166.303 193.478 178.674 1.00 185.26 ? 628 LYS H NZ  1 
ATOM 5357 N N   . GLU C 1 320 ? 160.980 194.590 175.037 1.00 186.15 ? 629 GLU H N   1 
ATOM 5358 C CA  . GLU C 1 320 ? 159.667 194.889 174.487 1.00 186.15 ? 629 GLU H CA  1 
ATOM 5359 C C   . GLU C 1 320 ? 159.703 196.207 173.724 1.00 186.15 ? 629 GLU H C   1 
ATOM 5360 O O   . GLU C 1 320 ? 160.071 197.245 174.282 1.00 186.15 ? 629 GLU H O   1 
ATOM 5361 C CB  . GLU C 1 320 ? 158.616 194.922 175.604 1.00 186.15 ? 629 GLU H CB  1 
ATOM 5362 C CG  . GLU C 1 320 ? 158.958 195.832 176.774 1.00 186.15 ? 629 GLU H CG  1 
ATOM 5363 C CD  . GLU C 1 320 ? 159.801 195.130 177.824 1.00 186.15 ? 629 GLU H CD  1 
ATOM 5364 O OE1 . GLU C 1 320 ? 160.362 194.058 177.519 1.00 186.15 ? 629 GLU H OE1 1 
ATOM 5365 O OE2 . GLU C 1 320 ? 159.900 195.648 178.956 1.00 186.15 ? 629 GLU H OE2 1 
ATOM 5366 N N   . ILE C 1 321 ? 159.338 196.152 172.442 1.00 203.04 ? 630 ILE H N   1 
ATOM 5367 C CA  . ILE C 1 321 ? 159.145 197.329 171.602 1.00 203.04 ? 630 ILE H CA  1 
ATOM 5368 C C   . ILE C 1 321 ? 157.800 197.184 170.904 1.00 203.04 ? 630 ILE H C   1 
ATOM 5369 O O   . ILE C 1 321 ? 157.509 196.131 170.326 1.00 203.04 ? 630 ILE H O   1 
ATOM 5370 C CB  . ILE C 1 321 ? 160.269 197.514 170.562 1.00 203.04 ? 630 ILE H CB  1 
ATOM 5371 C CG1 . ILE C 1 321 ? 161.623 197.754 171.234 1.00 203.04 ? 630 ILE H CG1 1 
ATOM 5372 C CG2 . ILE C 1 321 ? 159.951 198.672 169.626 1.00 203.04 ? 630 ILE H CG2 1 
ATOM 5373 C CD1 . ILE C 1 321 ? 162.412 196.495 171.476 1.00 203.04 ? 630 ILE H CD1 1 
ATOM 5374 N N   . THR C 1 322 ? 156.987 198.233 170.956 1.00 199.04 ? 631 THR H N   1 
ATOM 5375 C CA  . THR C 1 322 ? 155.653 198.221 170.377 1.00 199.04 ? 631 THR H CA  1 
ATOM 5376 C C   . THR C 1 322 ? 155.539 199.263 169.272 1.00 199.04 ? 631 THR H C   1 
ATOM 5377 O O   . THR C 1 322 ? 156.164 200.327 169.337 1.00 199.04 ? 631 THR H O   1 
ATOM 5378 C CB  . THR C 1 322 ? 154.585 198.475 171.446 1.00 199.04 ? 631 THR H CB  1 
ATOM 5379 O OG1 . THR C 1 322 ? 153.280 198.369 170.862 1.00 199.04 ? 631 THR H OG1 1 
ATOM 5380 C CG2 . THR C 1 322 ? 154.759 199.848 172.071 1.00 199.04 ? 631 THR H CG2 1 
ATOM 5381 N N   . ASP C 1 323 ? 154.759 198.932 168.242 1.00 217.24 ? 632 ASP H N   1 
ATOM 5382 C CA  . ASP C 1 323 ? 154.467 199.901 167.192 1.00 217.24 ? 632 ASP H CA  1 
ATOM 5383 C C   . ASP C 1 323 ? 153.496 200.967 167.679 1.00 217.24 ? 632 ASP H C   1 
ATOM 5384 O O   . ASP C 1 323 ? 153.627 202.143 167.319 1.00 217.24 ? 632 ASP H O   1 
ATOM 5385 C CB  . ASP C 1 323 ? 153.901 199.192 165.962 1.00 217.24 ? 632 ASP H CB  1 
ATOM 5386 C CG  . ASP C 1 323 ? 153.910 200.071 164.727 1.00 217.24 ? 632 ASP H CG  1 
ATOM 5387 O OD1 . ASP C 1 323 ? 154.435 201.202 164.799 1.00 217.24 ? 632 ASP H OD1 1 
ATOM 5388 O OD2 . ASP C 1 323 ? 153.391 199.631 163.681 1.00 217.24 ? 632 ASP H OD2 1 
ATOM 5389 N N   . GLN C 1 324 ? 152.515 200.577 168.495 1.00 223.68 ? 633 GLN H N   1 
ATOM 5390 C CA  . GLN C 1 324 ? 151.527 201.539 168.968 1.00 223.68 ? 633 GLN H CA  1 
ATOM 5391 C C   . GLN C 1 324 ? 152.183 202.652 169.773 1.00 223.68 ? 633 GLN H C   1 
ATOM 5392 O O   . GLN C 1 324 ? 151.773 203.814 169.685 1.00 223.68 ? 633 GLN H O   1 
ATOM 5393 C CB  . GLN C 1 324 ? 150.454 200.833 169.795 1.00 223.68 ? 633 GLN H CB  1 
ATOM 5394 C CG  . GLN C 1 324 ? 149.327 201.749 170.253 1.00 223.68 ? 633 GLN H CG  1 
ATOM 5395 C CD  . GLN C 1 324 ? 148.642 202.459 169.103 1.00 223.68 ? 633 GLN H CD  1 
ATOM 5396 O OE1 . GLN C 1 324 ? 148.873 203.644 168.863 1.00 223.68 ? 633 GLN H OE1 1 
ATOM 5397 N NE2 . GLN C 1 324 ? 147.788 201.738 168.386 1.00 223.68 ? 633 GLN H NE2 1 
ATOM 5398 N N   . GLY C 1 325 ? 153.207 202.318 170.561 1.00 214.71 ? 634 GLY H N   1 
ATOM 5399 C CA  . GLY C 1 325 ? 153.899 203.343 171.328 1.00 214.71 ? 634 GLY H CA  1 
ATOM 5400 C C   . GLY C 1 325 ? 154.583 204.368 170.445 1.00 214.71 ? 634 GLY H C   1 
ATOM 5401 O O   . GLY C 1 325 ? 154.491 205.575 170.682 1.00 214.71 ? 634 GLY H O   1 
ATOM 5402 N N   . ALA C 1 326 ? 155.281 203.898 169.408 1.00 207.50 ? 635 ALA H N   1 
ATOM 5403 C CA  . ALA C 1 326 ? 155.911 204.818 168.470 1.00 207.50 ? 635 ALA H CA  1 
ATOM 5404 C C   . ALA C 1 326 ? 154.871 205.660 167.745 1.00 207.50 ? 635 ALA H C   1 
ATOM 5405 O O   . ALA C 1 326 ? 155.055 206.870 167.562 1.00 207.50 ? 635 ALA H O   1 
ATOM 5406 C CB  . ALA C 1 326 ? 156.769 204.041 167.472 1.00 207.50 ? 635 ALA H CB  1 
ATOM 5407 N N   . THR C 1 327 ? 153.762 205.039 167.333 1.00 223.23 ? 636 THR H N   1 
ATOM 5408 C CA  . THR C 1 327 ? 152.714 205.785 166.644 1.00 223.23 ? 636 THR H CA  1 
ATOM 5409 C C   . THR C 1 327 ? 152.143 206.875 167.537 1.00 223.23 ? 636 THR H C   1 
ATOM 5410 O O   . THR C 1 327 ? 151.905 207.998 167.083 1.00 223.23 ? 636 THR H O   1 
ATOM 5411 C CB  . THR C 1 327 ? 151.599 204.846 166.186 1.00 223.23 ? 636 THR H CB  1 
ATOM 5412 O OG1 . THR C 1 327 ? 151.041 204.173 167.321 1.00 223.23 ? 636 THR H OG1 1 
ATOM 5413 C CG2 . THR C 1 327 ? 152.128 203.822 165.192 1.00 223.23 ? 636 THR H CG2 1 
ATOM 5414 N N   . LEU C 1 328 ? 151.918 206.560 168.813 1.00 212.91 ? 637 LEU H N   1 
ATOM 5415 C CA  . LEU C 1 328 ? 151.375 207.549 169.735 1.00 212.91 ? 637 LEU H CA  1 
ATOM 5416 C C   . LEU C 1 328 ? 152.378 208.661 170.015 1.00 212.91 ? 637 LEU H C   1 
ATOM 5417 O O   . LEU C 1 328 ? 151.997 209.832 170.103 1.00 212.91 ? 637 LEU H O   1 
ATOM 5418 C CB  . LEU C 1 328 ? 150.934 206.871 171.032 1.00 212.91 ? 637 LEU H CB  1 
ATOM 5419 C CG  . LEU C 1 328 ? 149.557 206.206 170.965 1.00 212.91 ? 637 LEU H CG  1 
ATOM 5420 C CD1 . LEU C 1 328 ? 149.103 205.747 172.339 1.00 212.91 ? 637 LEU H CD1 1 
ATOM 5421 C CD2 . LEU C 1 328 ? 148.540 207.158 170.359 1.00 212.91 ? 637 LEU H CD2 1 
ATOM 5422 N N   . ILE C 1 329 ? 153.662 208.323 170.164 1.00 199.15 ? 638 ILE H N   1 
ATOM 5423 C CA  . ILE C 1 329 ? 154.655 209.363 170.408 1.00 199.15 ? 638 ILE H CA  1 
ATOM 5424 C C   . ILE C 1 329 ? 154.880 210.216 169.170 1.00 199.15 ? 638 ILE H C   1 
ATOM 5425 O O   . ILE C 1 329 ? 155.370 211.344 169.280 1.00 199.15 ? 638 ILE H O   1 
ATOM 5426 C CB  . ILE C 1 329 ? 155.985 208.757 170.899 1.00 199.15 ? 638 ILE H CB  1 
ATOM 5427 C CG1 . ILE C 1 329 ? 156.831 209.810 171.620 1.00 199.15 ? 638 ILE H CG1 1 
ATOM 5428 C CG2 . ILE C 1 329 ? 156.776 208.182 169.757 1.00 199.15 ? 638 ILE H CG2 1 
ATOM 5429 C CD1 . ILE C 1 329 ? 158.059 209.238 172.305 1.00 199.15 ? 638 ILE H CD1 1 
ATOM 5430 N N   . ALA C 1 330 ? 154.521 209.710 167.988 1.00 210.39 ? 639 ALA H N   1 
ATOM 5431 C CA  . ALA C 1 330 ? 154.712 210.486 166.767 1.00 210.39 ? 639 ALA H CA  1 
ATOM 5432 C C   . ALA C 1 330 ? 153.906 211.782 166.791 1.00 210.39 ? 639 ALA H C   1 
ATOM 5433 O O   . ALA C 1 330 ? 154.435 212.858 166.496 1.00 210.39 ? 639 ALA H O   1 
ATOM 5434 C CB  . ALA C 1 330 ? 154.337 209.643 165.548 1.00 210.39 ? 639 ALA H CB  1 
ATOM 5435 N N   . GLN C 1 331 ? 152.625 211.703 167.152 1.00 220.94 ? 640 GLN H N   1 
ATOM 5436 C CA  . GLN C 1 331 ? 151.742 212.859 167.071 1.00 220.94 ? 640 GLN H CA  1 
ATOM 5437 C C   . GLN C 1 331 ? 151.266 213.350 168.428 1.00 220.94 ? 640 GLN H C   1 
ATOM 5438 O O   . GLN C 1 331 ? 150.688 214.442 168.505 1.00 220.94 ? 640 GLN H O   1 
ATOM 5439 C CB  . GLN C 1 331 ? 150.522 212.540 166.192 1.00 220.94 ? 640 GLN H CB  1 
ATOM 5440 C CG  . GLN C 1 331 ? 149.284 212.054 166.947 1.00 220.94 ? 640 GLN H CG  1 
ATOM 5441 C CD  . GLN C 1 331 ? 149.387 210.618 167.425 1.00 220.94 ? 640 GLN H CD  1 
ATOM 5442 O OE1 . GLN C 1 331 ? 150.467 210.131 167.745 1.00 220.94 ? 640 GLN H OE1 1 
ATOM 5443 N NE2 . GLN C 1 331 ? 148.251 209.931 167.474 1.00 220.94 ? 640 GLN H NE2 1 
ATOM 5444 N N   . SER C 1 332 ? 151.485 212.584 169.497 1.00 213.94 ? 641 SER H N   1 
ATOM 5445 C CA  . SER C 1 332 ? 151.118 213.046 170.830 1.00 213.94 ? 641 SER H CA  1 
ATOM 5446 C C   . SER C 1 332 ? 151.931 214.270 171.221 1.00 213.94 ? 641 SER H C   1 
ATOM 5447 O O   . SER C 1 332 ? 151.421 215.182 171.882 1.00 213.94 ? 641 SER H O   1 
ATOM 5448 C CB  . SER C 1 332 ? 151.313 211.922 171.848 1.00 213.94 ? 641 SER H CB  1 
ATOM 5449 O OG  . SER C 1 332 ? 150.692 212.237 173.081 1.00 213.94 ? 641 SER H OG  1 
ATOM 5450 N N   . SER C 1 333 ? 153.202 214.301 170.831 1.00 211.29 ? 642 SER H N   1 
ATOM 5451 C CA  . SER C 1 333 ? 154.055 215.452 171.076 1.00 211.29 ? 642 SER H CA  1 
ATOM 5452 C C   . SER C 1 333 ? 154.832 215.773 169.813 1.00 211.29 ? 642 SER H C   1 
ATOM 5453 O O   . SER C 1 333 ? 155.368 214.873 169.160 1.00 211.29 ? 642 SER H O   1 
ATOM 5454 C CB  . SER C 1 333 ? 155.019 215.193 172.239 1.00 211.29 ? 642 SER H CB  1 
ATOM 5455 O OG  . SER C 1 333 ? 155.890 216.294 172.435 1.00 211.29 ? 642 SER H OG  1 
ATOM 5456 N N   . LYS C 1 334 ? 154.876 217.058 169.466 1.00 194.37 ? 643 LYS H N   1 
ATOM 5457 C CA  . LYS C 1 334 ? 155.756 217.493 168.394 1.00 194.37 ? 643 LYS H CA  1 
ATOM 5458 C C   . LYS C 1 334 ? 157.215 217.429 168.824 1.00 194.37 ? 643 LYS H C   1 
ATOM 5459 O O   . LYS C 1 334 ? 158.095 217.174 167.995 1.00 194.37 ? 643 LYS H O   1 
ATOM 5460 C CB  . LYS C 1 334 ? 155.379 218.902 167.945 1.00 194.37 ? 643 LYS H CB  1 
ATOM 5461 C CG  . LYS C 1 334 ? 153.943 219.028 167.446 1.00 194.37 ? 643 LYS H CG  1 
ATOM 5462 C CD  . LYS C 1 334 ? 153.757 218.385 166.077 1.00 194.37 ? 643 LYS H CD  1 
ATOM 5463 C CE  . LYS C 1 334 ? 153.066 217.028 166.175 1.00 194.37 ? 643 LYS H CE  1 
ATOM 5464 N NZ  . LYS C 1 334 ? 152.816 216.434 164.831 1.00 194.37 ? 643 LYS H NZ  1 
ATOM 5465 N N   . SER C 1 335 ? 157.490 217.659 170.110 1.00 199.26 ? 644 SER H N   1 
ATOM 5466 C CA  . SER C 1 335 ? 158.843 217.572 170.641 1.00 199.26 ? 644 SER H CA  1 
ATOM 5467 C C   . SER C 1 335 ? 159.305 216.142 170.887 1.00 199.26 ? 644 SER H C   1 
ATOM 5468 O O   . SER C 1 335 ? 160.493 215.857 170.709 1.00 199.26 ? 644 SER H O   1 
ATOM 5469 C CB  . SER C 1 335 ? 158.946 218.367 171.943 1.00 199.26 ? 644 SER H CB  1 
ATOM 5470 O OG  . SER C 1 335 ? 160.229 218.216 172.525 1.00 199.26 ? 644 SER H OG  1 
ATOM 5471 N N   . LEU C 1 336 ? 158.411 215.239 171.282 1.00 200.17 ? 645 LEU H N   1 
ATOM 5472 C CA  . LEU C 1 336 ? 158.787 213.861 171.599 1.00 200.17 ? 645 LEU H CA  1 
ATOM 5473 C C   . LEU C 1 336 ? 158.685 213.050 170.316 1.00 200.17 ? 645 LEU H C   1 
ATOM 5474 O O   . LEU C 1 336 ? 157.623 212.547 169.958 1.00 200.17 ? 645 LEU H O   1 
ATOM 5475 C CB  . LEU C 1 336 ? 157.911 213.264 172.692 1.00 200.17 ? 645 LEU H CB  1 
ATOM 5476 C CG  . LEU C 1 336 ? 158.294 213.561 174.139 1.00 200.17 ? 645 LEU H CG  1 
ATOM 5477 C CD1 . LEU C 1 336 ? 159.700 213.050 174.436 1.00 200.17 ? 645 LEU H CD1 1 
ATOM 5478 C CD2 . LEU C 1 336 ? 158.148 215.041 174.440 1.00 200.17 ? 645 LEU H CD2 1 
ATOM 5479 N N   . ARG C 1 337 ? 159.804 212.930 169.621 1.00 207.71 ? 646 ARG H N   1 
ATOM 5480 C CA  . ARG C 1 337 ? 159.899 212.129 168.407 1.00 207.71 ? 646 ARG H CA  1 
ATOM 5481 C C   . ARG C 1 337 ? 161.050 211.148 168.593 1.00 207.71 ? 646 ARG H C   1 
ATOM 5482 O O   . ARG C 1 337 ? 162.222 211.530 168.498 1.00 207.71 ? 646 ARG H O   1 
ATOM 5483 C CB  . ARG C 1 337 ? 160.100 213.014 167.181 1.00 207.71 ? 646 ARG H CB  1 
ATOM 5484 C CG  . ARG C 1 337 ? 159.243 214.270 167.149 1.00 207.71 ? 646 ARG H CG  1 
ATOM 5485 C CD  . ARG C 1 337 ? 157.966 214.033 166.359 1.00 207.71 ? 646 ARG H CD  1 
ATOM 5486 N NE  . ARG C 1 337 ? 156.945 215.038 166.631 1.00 207.71 ? 646 ARG H NE  1 
ATOM 5487 C CZ  . ARG C 1 337 ? 155.911 215.283 165.840 1.00 207.71 ? 646 ARG H CZ  1 
ATOM 5488 N N   . TYR C 1 338 ? 160.720 209.892 168.878 1.00 197.33 ? 647 TYR H N   1 
ATOM 5489 C CA  . TYR C 1 338 ? 161.704 208.819 168.980 1.00 197.33 ? 647 TYR H CA  1 
ATOM 5490 C C   . TYR C 1 338 ? 161.226 207.586 168.222 1.00 197.33 ? 647 TYR H C   1 
ATOM 5491 O O   . TYR C 1 338 ? 161.198 206.471 168.746 1.00 197.33 ? 647 TYR H O   1 
ATOM 5492 C CB  . TYR C 1 338 ? 162.017 208.466 170.430 1.00 197.33 ? 647 TYR H CB  1 
ATOM 5493 C CG  . TYR C 1 338 ? 163.266 207.628 170.551 1.00 197.33 ? 647 TYR H CG  1 
ATOM 5494 C CD1 . TYR C 1 338 ? 164.505 208.150 170.212 1.00 197.33 ? 647 TYR H CD1 1 
ATOM 5495 C CD2 . TYR C 1 338 ? 163.205 206.309 170.977 1.00 197.33 ? 647 TYR H CD2 1 
ATOM 5496 C CE1 . TYR C 1 338 ? 165.646 207.389 170.307 1.00 197.33 ? 647 TYR H CE1 1 
ATOM 5497 C CE2 . TYR C 1 338 ? 164.345 205.538 171.074 1.00 197.33 ? 647 TYR H CE2 1 
ATOM 5498 C CZ  . TYR C 1 338 ? 165.561 206.084 170.738 1.00 197.33 ? 647 TYR H CZ  1 
ATOM 5499 N N   . LEU C 1 339 ? 160.810 207.779 166.973 1.00 229.78 ? 648 LEU H N   1 
ATOM 5500 C CA  . LEU C 1 339 ? 160.426 206.651 166.125 1.00 229.78 ? 648 LEU H CA  1 
ATOM 5501 C C   . LEU C 1 339 ? 161.604 206.157 165.290 1.00 229.78 ? 648 LEU H C   1 
ATOM 5502 O O   . LEU C 1 339 ? 161.490 205.949 164.085 1.00 229.78 ? 648 LEU H O   1 
ATOM 5503 C CB  . LEU C 1 339 ? 159.262 207.054 165.227 1.00 229.78 ? 648 LEU H CB  1 
ATOM 5504 C CG  . LEU C 1 339 ? 157.862 207.151 165.828 1.00 229.78 ? 648 LEU H CG  1 
ATOM 5505 C CD1 . LEU C 1 339 ? 157.686 208.517 166.449 1.00 229.78 ? 648 LEU H CD1 1 
ATOM 5506 C CD2 . LEU C 1 339 ? 156.800 206.903 164.773 1.00 229.78 ? 648 LEU H CD2 1 
ATOM 5507 N N   . GLY C 1 340 ? 162.752 205.957 165.931 1.00 209.82 ? 649 GLY H N   1 
ATOM 5508 C CA  . GLY C 1 340 ? 163.912 205.416 165.250 1.00 209.82 ? 649 GLY H CA  1 
ATOM 5509 C C   . GLY C 1 340 ? 164.072 203.933 165.497 1.00 209.82 ? 649 GLY H C   1 
ATOM 5510 O O   . GLY C 1 340 ? 165.043 203.517 166.136 1.00 209.82 ? 649 GLY H O   1 
ATOM 5511 N N   . LEU C 1 341 ? 163.145 203.132 164.976 1.00 188.94 ? 650 LEU H N   1 
ATOM 5512 C CA  . LEU C 1 341 ? 163.022 201.743 165.403 1.00 188.94 ? 650 LEU H CA  1 
ATOM 5513 C C   . LEU C 1 341 ? 164.333 200.988 165.233 1.00 188.94 ? 650 LEU H C   1 
ATOM 5514 O O   . LEU C 1 341 ? 164.971 201.042 164.178 1.00 188.94 ? 650 LEU H O   1 
ATOM 5515 C CB  . LEU C 1 341 ? 161.907 201.047 164.624 1.00 188.94 ? 650 LEU H CB  1 
ATOM 5516 C CG  . LEU C 1 341 ? 160.491 201.543 164.920 1.00 188.94 ? 650 LEU H CG  1 
ATOM 5517 C CD1 . LEU C 1 341 ? 159.461 200.637 164.262 1.00 188.94 ? 650 LEU H CD1 1 
ATOM 5518 C CD2 . LEU C 1 341 ? 160.255 201.640 166.420 1.00 188.94 ? 650 LEU H CD2 1 
ATOM 5519 N N   . MET C 1 342 ? 164.732 200.291 166.291 1.00 177.15 ? 651 MET H N   1 
ATOM 5520 C CA  . MET C 1 342 ? 165.971 199.534 166.337 1.00 177.15 ? 651 MET H CA  1 
ATOM 5521 C C   . MET C 1 342 ? 165.688 198.194 166.993 1.00 177.15 ? 651 MET H C   1 
ATOM 5522 O O   . MET C 1 342 ? 164.910 198.117 167.948 1.00 177.15 ? 651 MET H O   1 
ATOM 5523 C CB  . MET C 1 342 ? 167.058 200.292 167.109 1.00 177.15 ? 651 MET H CB  1 
ATOM 5524 C CG  . MET C 1 342 ? 168.441 199.703 166.979 1.00 177.15 ? 651 MET H CG  1 
ATOM 5525 S SD  . MET C 1 342 ? 168.783 198.598 168.353 1.00 177.15 ? 651 MET H SD  1 
ATOM 5526 C CE  . MET C 1 342 ? 169.569 199.719 169.500 1.00 177.15 ? 651 MET H CE  1 
ATOM 5527 N N   . ARG C 1 343 ? 166.322 197.142 166.475 1.00 205.28 ? 652 ARG H N   1 
ATOM 5528 C CA  . ARG C 1 343 ? 166.097 195.774 166.947 1.00 205.28 ? 652 ARG H CA  1 
ATOM 5529 C C   . ARG C 1 343 ? 164.616 195.401 166.879 1.00 205.28 ? 652 ARG H C   1 
ATOM 5530 O O   . ARG C 1 343 ? 164.057 194.834 167.820 1.00 205.28 ? 652 ARG H O   1 
ATOM 5531 C CB  . ARG C 1 343 ? 166.645 195.579 168.362 1.00 205.28 ? 652 ARG H CB  1 
ATOM 5532 C CG  . ARG C 1 343 ? 167.037 194.145 168.681 1.00 205.28 ? 652 ARG H CG  1 
ATOM 5533 C CD  . ARG C 1 343 ? 168.495 193.876 168.355 1.00 205.28 ? 652 ARG H CD  1 
ATOM 5534 N NE  . ARG C 1 343 ? 168.726 192.473 168.027 1.00 205.28 ? 652 ARG H NE  1 
ATOM 5535 C CZ  . ARG C 1 343 ? 168.509 191.464 168.859 1.00 205.28 ? 652 ARG H CZ  1 
ATOM 5536 N N   . CYS C 1 344 ? 163.972 195.731 165.761 1.00 234.10 ? 653 CYS H N   1 
ATOM 5537 C CA  . CYS C 1 344 ? 162.555 195.441 165.530 1.00 234.10 ? 653 CYS H CA  1 
ATOM 5538 C C   . CYS C 1 344 ? 162.449 194.496 164.331 1.00 234.10 ? 653 CYS H C   1 
ATOM 5539 O O   . CYS C 1 344 ? 162.300 194.941 163.190 1.00 234.10 ? 653 CYS H O   1 
ATOM 5540 C CB  . CYS C 1 344 ? 161.763 196.737 165.302 1.00 234.10 ? 653 CYS H CB  1 
ATOM 5541 S SG  . CYS C 1 344 ? 161.930 197.972 166.616 1.00 234.10 ? 653 CYS H SG  1 
ATOM 5542 N N   . ASP C 1 345 ? 162.523 193.188 164.593 1.00 259.72 ? 654 ASP H N   1 
ATOM 5543 C CA  . ASP C 1 345 ? 162.534 192.216 163.501 1.00 259.72 ? 654 ASP H CA  1 
ATOM 5544 C C   . ASP C 1 345 ? 161.168 192.091 162.835 1.00 259.72 ? 654 ASP H C   1 
ATOM 5545 O O   . ASP C 1 345 ? 161.068 192.124 161.602 1.00 259.72 ? 654 ASP H O   1 
ATOM 5546 C CB  . ASP C 1 345 ? 162.996 190.851 164.015 1.00 259.72 ? 654 ASP H CB  1 
ATOM 5547 C CG  . ASP C 1 345 ? 164.505 190.725 164.064 1.00 259.72 ? 654 ASP H CG  1 
ATOM 5548 O OD1 . ASP C 1 345 ? 165.189 191.396 163.263 1.00 259.72 ? 654 ASP H OD1 1 
ATOM 5549 O OD2 . ASP C 1 345 ? 165.008 189.945 164.898 1.00 259.72 ? 654 ASP H OD2 1 
ATOM 5550 N N   . LYS C 1 346 ? 160.106 191.953 163.627 1.00 303.21 ? 655 LYS H N   1 
ATOM 5551 C CA  . LYS C 1 346 ? 158.766 191.683 163.101 1.00 303.21 ? 655 LYS H CA  1 
ATOM 5552 C C   . LYS C 1 346 ? 158.085 193.007 162.784 1.00 303.21 ? 655 LYS H C   1 
ATOM 5553 O O   . LYS C 1 346 ? 157.539 193.680 163.659 1.00 303.21 ? 655 LYS H O   1 
ATOM 5554 C CB  . LYS C 1 346 ? 157.953 190.858 164.090 1.00 303.21 ? 655 LYS H CB  1 
ATOM 5555 C CG  . LYS C 1 346 ? 156.724 190.194 163.485 1.00 303.21 ? 655 LYS H CG  1 
ATOM 5556 C CD  . LYS C 1 346 ? 157.075 189.351 162.269 1.00 303.21 ? 655 LYS H CD  1 
ATOM 5557 C CE  . LYS C 1 346 ? 155.828 188.733 161.653 1.00 303.21 ? 655 LYS H CE  1 
ATOM 5558 N NZ  . LYS C 1 346 ? 156.110 188.083 160.345 1.00 303.21 ? 655 LYS H NZ  1 
ATOM 5559 N N   . VAL C 1 347 ? 158.115 193.382 161.506 1.00 340.73 ? 656 VAL H N   1 
ATOM 5560 C CA  . VAL C 1 347 ? 157.480 194.607 161.040 1.00 340.73 ? 656 VAL H CA  1 
ATOM 5561 C C   . VAL C 1 347 ? 157.175 194.447 159.558 1.00 340.73 ? 656 VAL H C   1 
ATOM 5562 O O   . VAL C 1 347 ? 157.893 193.758 158.827 1.00 340.73 ? 656 VAL H O   1 
ATOM 5563 C CB  . VAL C 1 347 ? 158.368 195.845 161.310 1.00 340.73 ? 656 VAL H CB  1 
ATOM 5564 C CG1 . VAL C 1 347 ? 159.630 195.800 160.459 1.00 340.73 ? 656 VAL H CG1 1 
ATOM 5565 C CG2 . VAL C 1 347 ? 157.592 197.135 161.069 1.00 340.73 ? 656 VAL H CG2 1 
ATOM 5566 N N   . ASN C 1 348 ? 156.088 195.072 159.121 1.00 379.98 ? 657 ASN H N   1 
ATOM 5567 C CA  . ASN C 1 348 ? 155.696 195.041 157.723 1.00 379.98 ? 657 ASN H CA  1 
ATOM 5568 C C   . ASN C 1 348 ? 156.317 196.233 156.996 1.00 379.98 ? 657 ASN H C   1 
ATOM 5569 O O   . ASN C 1 348 ? 157.143 196.965 157.548 1.00 379.98 ? 657 ASN H O   1 
ATOM 5570 C CB  . ASN C 1 348 ? 154.175 195.021 157.604 1.00 379.98 ? 657 ASN H CB  1 
ATOM 5571 C CG  . ASN C 1 348 ? 153.691 194.140 156.469 1.00 379.98 ? 657 ASN H CG  1 
ATOM 5572 O OD1 . ASN C 1 348 ? 154.489 193.533 155.756 1.00 379.98 ? 657 ASN H OD1 1 
ATOM 5573 N ND2 . ASN C 1 348 ? 152.376 194.063 156.299 1.00 379.98 ? 657 ASN H ND2 1 
ATOM 5574 N N   . GLU C 1 349 ? 155.921 196.440 155.743 1.00 391.36 ? 658 GLU H N   1 
ATOM 5575 C CA  . GLU C 1 349 ? 156.433 197.531 154.916 1.00 391.36 ? 658 GLU H CA  1 
ATOM 5576 C C   . GLU C 1 349 ? 155.418 198.657 154.773 1.00 391.36 ? 658 GLU H C   1 
ATOM 5577 O O   . GLU C 1 349 ? 155.296 199.269 153.709 1.00 391.36 ? 658 GLU H O   1 
ATOM 5578 C CB  . GLU C 1 349 ? 156.847 197.002 153.546 1.00 391.36 ? 658 GLU H CB  1 
ATOM 5579 C CG  . GLU C 1 349 ? 158.194 196.293 153.539 1.00 391.36 ? 658 GLU H CG  1 
ATOM 5580 C CD  . GLU C 1 349 ? 158.079 194.805 153.811 1.00 391.36 ? 658 GLU H CD  1 
ATOM 5581 O OE1 . GLU C 1 349 ? 157.114 194.392 154.488 1.00 391.36 ? 658 GLU H OE1 1 
ATOM 5582 O OE2 . GLU C 1 349 ? 158.958 194.047 153.349 1.00 391.36 ? 658 GLU H OE2 1 
ATOM 5583 N N   . VAL C 1 350 ? 154.673 198.948 155.839 1.00 452.64 ? 659 VAL H N   1 
ATOM 5584 C CA  . VAL C 1 350 ? 153.639 199.975 155.767 1.00 452.64 ? 659 VAL H CA  1 
ATOM 5585 C C   . VAL C 1 350 ? 154.234 201.363 155.973 1.00 452.64 ? 659 VAL H C   1 
ATOM 5586 O O   . VAL C 1 350 ? 153.815 202.329 155.325 1.00 452.64 ? 659 VAL H O   1 
ATOM 5587 C CB  . VAL C 1 350 ? 152.526 199.671 156.786 1.00 452.64 ? 659 VAL H CB  1 
ATOM 5588 C CG1 . VAL C 1 350 ? 151.503 200.796 156.816 1.00 452.64 ? 659 VAL H CG1 1 
ATOM 5589 C CG2 . VAL C 1 350 ? 151.857 198.345 156.456 1.00 452.64 ? 659 VAL H CG2 1 
ATOM 5590 N N   . THR C 1 351 ? 155.216 201.487 156.871 1.00 445.93 ? 660 THR H N   1 
ATOM 5591 C CA  . THR C 1 351 ? 155.798 202.794 157.167 1.00 445.93 ? 660 THR H CA  1 
ATOM 5592 C C   . THR C 1 351 ? 156.402 203.424 155.918 1.00 445.93 ? 660 THR H C   1 
ATOM 5593 O O   . THR C 1 351 ? 156.102 204.577 155.580 1.00 445.93 ? 660 THR H O   1 
ATOM 5594 C CB  . THR C 1 351 ? 156.858 202.660 158.263 1.00 445.93 ? 660 THR H CB  1 
ATOM 5595 O OG1 . THR C 1 351 ? 156.217 202.471 159.531 1.00 445.93 ? 660 THR H OG1 1 
ATOM 5596 C CG2 . THR C 1 351 ? 157.735 203.903 158.321 1.00 445.93 ? 660 THR H CG2 1 
ATOM 5597 N N   . VAL C 1 352 ? 157.228 202.658 155.197 1.00 459.08 ? 661 VAL H N   1 
ATOM 5598 C CA  . VAL C 1 352 ? 157.898 203.156 154.001 1.00 459.08 ? 661 VAL H CA  1 
ATOM 5599 C C   . VAL C 1 352 ? 156.936 203.443 152.861 1.00 459.08 ? 661 VAL H C   1 
ATOM 5600 O O   . VAL C 1 352 ? 157.345 204.020 151.848 1.00 459.08 ? 661 VAL H O   1 
ATOM 5601 C CB  . VAL C 1 352 ? 158.968 202.151 153.523 1.00 459.08 ? 661 VAL H CB  1 
ATOM 5602 C CG1 . VAL C 1 352 ? 160.018 201.936 154.603 1.00 459.08 ? 661 VAL H CG1 1 
ATOM 5603 C CG2 . VAL C 1 352 ? 158.321 200.833 153.127 1.00 459.08 ? 661 VAL H CG2 1 
ATOM 5604 N N   . GLU C 1 353 ? 155.668 203.044 152.997 1.00 518.33 ? 662 GLU H N   1 
ATOM 5605 C CA  . GLU C 1 353 ? 154.657 203.294 151.981 1.00 518.33 ? 662 GLU H CA  1 
ATOM 5606 C C   . GLU C 1 353 ? 153.620 204.329 152.395 1.00 518.33 ? 662 GLU H C   1 
ATOM 5607 O O   . GLU C 1 353 ? 152.958 204.896 151.521 1.00 518.33 ? 662 GLU H O   1 
ATOM 5608 C CB  . GLU C 1 353 ? 153.942 201.985 151.615 1.00 518.33 ? 662 GLU H CB  1 
ATOM 5609 C CG  . GLU C 1 353 ? 153.257 202.000 150.258 1.00 518.33 ? 662 GLU H CG  1 
ATOM 5610 C CD  . GLU C 1 353 ? 151.778 202.317 150.355 1.00 518.33 ? 662 GLU H CD  1 
ATOM 5611 O OE1 . GLU C 1 353 ? 151.170 202.011 151.400 1.00 518.33 ? 662 GLU H OE1 1 
ATOM 5612 O OE2 . GLU C 1 353 ? 151.224 202.873 149.382 1.00 518.33 ? 662 GLU H OE2 1 
ATOM 5613 N N   . GLN C 1 354 ? 153.466 204.594 153.692 1.00 553.72 ? 663 GLN H N   1 
ATOM 5614 C CA  . GLN C 1 354 ? 152.467 205.533 154.188 1.00 553.72 ? 663 GLN H CA  1 
ATOM 5615 C C   . GLN C 1 354 ? 153.061 206.834 154.707 1.00 553.72 ? 663 GLN H C   1 
ATOM 5616 O O   . GLN C 1 354 ? 152.566 207.915 154.368 1.00 553.72 ? 663 GLN H O   1 
ATOM 5617 C CB  . GLN C 1 354 ? 151.627 204.875 155.294 1.00 553.72 ? 663 GLN H CB  1 
ATOM 5618 C CG  . GLN C 1 354 ? 150.623 205.815 155.945 1.00 553.72 ? 663 GLN H CG  1 
ATOM 5619 C CD  . GLN C 1 354 ? 149.275 205.814 155.250 1.00 553.72 ? 663 GLN H CD  1 
ATOM 5620 O OE1 . GLN C 1 354 ? 149.185 205.579 154.045 1.00 553.72 ? 663 GLN H OE1 1 
ATOM 5621 N NE2 . GLN C 1 354 ? 148.219 206.084 156.009 1.00 553.72 ? 663 GLN H NE2 1 
ATOM 5622 N N   . LEU C 1 355 ? 154.114 206.770 155.528 1.00 529.85 ? 664 LEU H N   1 
ATOM 5623 C CA  . LEU C 1 355 ? 154.643 208.003 156.101 1.00 529.85 ? 664 LEU H CA  1 
ATOM 5624 C C   . LEU C 1 355 ? 155.322 208.894 155.070 1.00 529.85 ? 664 LEU H C   1 
ATOM 5625 O O   . LEU C 1 355 ? 155.616 210.053 155.379 1.00 529.85 ? 664 LEU H O   1 
ATOM 5626 C CB  . LEU C 1 355 ? 155.614 207.695 157.241 1.00 529.85 ? 664 LEU H CB  1 
ATOM 5627 C CG  . LEU C 1 355 ? 154.982 207.639 158.634 1.00 529.85 ? 664 LEU H CG  1 
ATOM 5628 C CD1 . LEU C 1 355 ? 154.219 206.338 158.842 1.00 529.85 ? 664 LEU H CD1 1 
ATOM 5629 C CD2 . LEU C 1 355 ? 156.036 207.833 159.716 1.00 529.85 ? 664 LEU H CD2 1 
ATOM 5630 N N   . VAL C 1 356 ? 155.580 208.386 153.863 1.00 546.00 ? 665 VAL H N   1 
ATOM 5631 C CA  . VAL C 1 356 ? 156.150 209.223 152.809 1.00 546.00 ? 665 VAL H CA  1 
ATOM 5632 C C   . VAL C 1 356 ? 155.176 210.332 152.431 1.00 546.00 ? 665 VAL H C   1 
ATOM 5633 O O   . VAL C 1 356 ? 155.552 211.506 152.326 1.00 546.00 ? 665 VAL H O   1 
ATOM 5634 C CB  . VAL C 1 356 ? 156.527 208.364 151.589 1.00 546.00 ? 665 VAL H CB  1 
ATOM 5635 C CG1 . VAL C 1 356 ? 156.883 209.249 150.405 1.00 546.00 ? 665 VAL H CG1 1 
ATOM 5636 C CG2 . VAL C 1 356 ? 157.676 207.425 151.936 1.00 546.00 ? 665 VAL H CG2 1 
ATOM 5637 N N   . GLN C 1 357 ? 153.907 209.977 152.233 1.00 557.40 ? 666 GLN H N   1 
ATOM 5638 C CA  . GLN C 1 357 ? 152.875 210.961 151.934 1.00 557.40 ? 666 GLN H CA  1 
ATOM 5639 C C   . GLN C 1 357 ? 152.226 211.538 153.184 1.00 557.40 ? 666 GLN H C   1 
ATOM 5640 O O   . GLN C 1 357 ? 151.660 212.635 153.119 1.00 557.40 ? 666 GLN H O   1 
ATOM 5641 C CB  . GLN C 1 357 ? 151.801 210.349 151.028 1.00 557.40 ? 666 GLN H CB  1 
ATOM 5642 C CG  . GLN C 1 357 ? 151.123 209.117 151.601 1.00 557.40 ? 666 GLN H CG  1 
ATOM 5643 C CD  . GLN C 1 357 ? 151.709 207.828 151.054 1.00 557.40 ? 666 GLN H CD  1 
ATOM 5644 O OE1 . GLN C 1 357 ? 152.807 207.820 150.496 1.00 557.40 ? 666 GLN H OE1 1 
ATOM 5645 N NE2 . GLN C 1 357 ? 150.978 206.730 151.212 1.00 557.40 ? 666 GLN H NE2 1 
ATOM 5646 N N   . GLN C 1 358 ? 152.283 210.827 154.313 1.00 553.23 ? 667 GLN H N   1 
ATOM 5647 C CA  . GLN C 1 358 ? 151.814 211.410 155.566 1.00 553.23 ? 667 GLN H CA  1 
ATOM 5648 C C   . GLN C 1 358 ? 152.739 212.529 156.032 1.00 553.23 ? 667 GLN H C   1 
ATOM 5649 O O   . GLN C 1 358 ? 152.273 213.553 156.547 1.00 553.23 ? 667 GLN H O   1 
ATOM 5650 C CB  . GLN C 1 358 ? 151.697 210.327 156.638 1.00 553.23 ? 667 GLN H CB  1 
ATOM 5651 C CG  . GLN C 1 358 ? 150.908 210.751 157.868 1.00 553.23 ? 667 GLN H CG  1 
ATOM 5652 C CD  . GLN C 1 358 ? 149.411 210.763 157.626 1.00 553.23 ? 667 GLN H CD  1 
ATOM 5653 O OE1 . GLN C 1 358 ? 148.858 209.836 157.034 1.00 553.23 ? 667 GLN H OE1 1 
ATOM 5654 N NE2 . GLN C 1 358 ? 148.746 211.817 158.086 1.00 553.23 ? 667 GLN H NE2 1 
ATOM 5655 N N   . TYR C 1 359 ? 154.050 212.353 155.857 1.00 553.27 ? 668 TYR H N   1 
ATOM 5656 C CA  . TYR C 1 359 ? 155.059 213.335 156.260 1.00 553.27 ? 668 TYR H CA  1 
ATOM 5657 C C   . TYR C 1 359 ? 155.961 213.617 155.066 1.00 553.27 ? 668 TYR H C   1 
ATOM 5658 O O   . TYR C 1 359 ? 157.070 213.074 154.967 1.00 553.27 ? 668 TYR H O   1 
ATOM 5659 C CB  . TYR C 1 359 ? 155.878 212.836 157.452 1.00 553.27 ? 668 TYR H CB  1 
ATOM 5660 C CG  . TYR C 1 359 ? 155.103 212.723 158.744 1.00 553.27 ? 668 TYR H CG  1 
ATOM 5661 C CD1 . TYR C 1 359 ? 154.171 213.684 159.106 1.00 553.27 ? 668 TYR H CD1 1 
ATOM 5662 C CD2 . TYR C 1 359 ? 155.312 211.656 159.607 1.00 553.27 ? 668 TYR H CD2 1 
ATOM 5663 C CE1 . TYR C 1 359 ? 153.465 213.584 160.286 1.00 553.27 ? 668 TYR H CE1 1 
ATOM 5664 C CE2 . TYR C 1 359 ? 154.613 211.547 160.789 1.00 553.27 ? 668 TYR H CE2 1 
ATOM 5665 C CZ  . TYR C 1 359 ? 153.690 212.514 161.124 1.00 553.27 ? 668 TYR H CZ  1 
ATOM 5666 N N   . PRO C 1 360 ? 155.519 214.467 154.133 1.00 553.32 ? 669 PRO H N   1 
ATOM 5667 C CA  . PRO C 1 360 ? 156.317 214.702 152.921 1.00 553.32 ? 669 PRO H CA  1 
ATOM 5668 C C   . PRO C 1 360 ? 157.427 215.728 153.084 1.00 553.32 ? 669 PRO H C   1 
ATOM 5669 O O   . PRO C 1 360 ? 158.349 215.742 152.257 1.00 553.32 ? 669 PRO H O   1 
ATOM 5670 C CB  . PRO C 1 360 ? 155.273 215.185 151.908 1.00 553.32 ? 669 PRO H CB  1 
ATOM 5671 C CG  . PRO C 1 360 ? 154.249 215.877 152.749 1.00 553.32 ? 669 PRO H CG  1 
ATOM 5672 C CD  . PRO C 1 360 ? 154.240 215.200 154.104 1.00 553.32 ? 669 PRO H CD  1 
ATOM 5673 N N   . HIS C 1 361 ? 157.379 216.577 154.108 1.00 528.33 ? 670 HIS H N   1 
ATOM 5674 C CA  . HIS C 1 361 ? 158.341 217.659 154.266 1.00 528.33 ? 670 HIS H CA  1 
ATOM 5675 C C   . HIS C 1 361 ? 159.432 217.343 155.281 1.00 528.33 ? 670 HIS H C   1 
ATOM 5676 O O   . HIS C 1 361 ? 160.117 218.260 155.746 1.00 528.33 ? 670 HIS H O   1 
ATOM 5677 C CB  . HIS C 1 361 ? 157.621 218.952 154.660 1.00 528.33 ? 670 HIS H CB  1 
ATOM 5678 C CG  . HIS C 1 361 ? 156.972 218.899 156.009 1.00 528.33 ? 670 HIS H CG  1 
ATOM 5679 N ND1 . HIS C 1 361 ? 155.668 218.492 156.192 1.00 528.33 ? 670 HIS H ND1 1 
ATOM 5680 C CD2 . HIS C 1 361 ? 157.445 219.208 157.239 1.00 528.33 ? 670 HIS H CD2 1 
ATOM 5681 C CE1 . HIS C 1 361 ? 155.367 218.548 157.477 1.00 528.33 ? 670 HIS H CE1 1 
ATOM 5682 N NE2 . HIS C 1 361 ? 156.428 218.980 158.134 1.00 528.33 ? 670 HIS H NE2 1 
ATOM 5683 N N   . ILE C 1 362 ? 159.606 216.073 155.640 1.00 492.91 ? 671 ILE H N   1 
ATOM 5684 C CA  . ILE C 1 362 ? 160.578 215.656 156.646 1.00 492.91 ? 671 ILE H CA  1 
ATOM 5685 C C   . ILE C 1 362 ? 161.541 214.659 156.014 1.00 492.91 ? 671 ILE H C   1 
ATOM 5686 O O   . ILE C 1 362 ? 161.110 213.703 155.359 1.00 492.91 ? 671 ILE H O   1 
ATOM 5687 C CB  . ILE C 1 362 ? 159.885 215.049 157.880 1.00 492.91 ? 671 ILE H CB  1 
ATOM 5688 C CG1 . ILE C 1 362 ? 158.790 215.990 158.387 1.00 492.91 ? 671 ILE H CG1 1 
ATOM 5689 C CG2 . ILE C 1 362 ? 160.895 214.773 158.981 1.00 492.91 ? 671 ILE H CG2 1 
ATOM 5690 C CD1 . ILE C 1 362 ? 157.980 215.428 159.533 1.00 492.91 ? 671 ILE H CD1 1 
ATOM 5691 N N   . THR C 1 363 ? 162.840 214.888 156.201 1.00 387.40 ? 672 THR H N   1 
ATOM 5692 C CA  . THR C 1 363 ? 163.876 213.983 155.717 1.00 387.40 ? 672 THR H CA  1 
ATOM 5693 C C   . THR C 1 363 ? 164.321 212.969 156.765 1.00 387.40 ? 672 THR H C   1 
ATOM 5694 O O   . THR C 1 363 ? 165.231 212.183 156.491 1.00 387.40 ? 672 THR H O   1 
ATOM 5695 C CB  . THR C 1 363 ? 165.092 214.779 155.228 1.00 387.40 ? 672 THR H CB  1 
ATOM 5696 O OG1 . THR C 1 363 ? 165.604 215.585 156.297 1.00 387.40 ? 672 THR H OG1 1 
ATOM 5697 C CG2 . THR C 1 363 ? 164.706 215.677 154.064 1.00 387.40 ? 672 THR H CG2 1 
ATOM 5698 N N   . PHE C 1 364 ? 163.726 212.993 157.960 1.00 356.45 ? 673 PHE H N   1 
ATOM 5699 C CA  . PHE C 1 364 ? 163.971 212.019 159.024 1.00 356.45 ? 673 PHE H CA  1 
ATOM 5700 C C   . PHE C 1 364 ? 165.412 211.990 159.528 1.00 356.45 ? 673 PHE H C   1 
ATOM 5701 O O   . PHE C 1 364 ? 166.292 212.666 158.986 1.00 356.45 ? 673 PHE H O   1 
ATOM 5702 C CB  . PHE C 1 364 ? 163.542 210.618 158.578 1.00 356.45 ? 673 PHE H CB  1 
ATOM 5703 C CG  . PHE C 1 364 ? 162.061 210.365 158.718 1.00 356.45 ? 673 PHE H CG  1 
ATOM 5704 C CD1 . PHE C 1 364 ? 161.276 211.202 159.496 1.00 356.45 ? 673 PHE H CD1 1 
ATOM 5705 C CD2 . PHE C 1 364 ? 161.460 209.285 158.093 1.00 356.45 ? 673 PHE H CD2 1 
ATOM 5706 C CE1 . PHE C 1 364 ? 159.922 210.973 159.637 1.00 356.45 ? 673 PHE H CE1 1 
ATOM 5707 C CE2 . PHE C 1 364 ? 160.102 209.052 158.233 1.00 356.45 ? 673 PHE H CE2 1 
ATOM 5708 C CZ  . PHE C 1 364 ? 159.335 209.898 159.005 1.00 356.45 ? 673 PHE H CZ  1 
ATOM 5709 N N   . SER C 1 365 ? 165.643 211.212 160.590 1.00 289.76 ? 674 SER H N   1 
ATOM 5710 C CA  . SER C 1 365 ? 166.939 211.163 161.252 1.00 289.76 ? 674 SER H CA  1 
ATOM 5711 C C   . SER C 1 365 ? 167.353 209.764 161.686 1.00 289.76 ? 674 SER H C   1 
ATOM 5712 O O   . SER C 1 365 ? 168.387 209.626 162.348 1.00 289.76 ? 674 SER H O   1 
ATOM 5713 C CB  . SER C 1 365 ? 166.944 212.093 162.476 1.00 289.76 ? 674 SER H CB  1 
ATOM 5714 O OG  . SER C 1 365 ? 168.165 211.998 163.186 1.00 289.76 ? 674 SER H OG  1 
ATOM 5715 N N   . THR C 1 366 ? 166.588 208.732 161.352 1.00 222.49 ? 675 THR H N   1 
ATOM 5716 C CA  . THR C 1 366 ? 166.930 207.370 161.725 1.00 222.49 ? 675 THR H CA  1 
ATOM 5717 C C   . THR C 1 366 ? 168.023 206.806 160.820 1.00 222.49 ? 675 THR H C   1 
ATOM 5718 O O   . THR C 1 366 ? 168.247 207.274 159.701 1.00 222.49 ? 675 THR H O   1 
ATOM 5719 C CB  . THR C 1 366 ? 165.698 206.472 161.657 1.00 222.49 ? 675 THR H CB  1 
ATOM 5720 O OG1 . THR C 1 366 ? 166.063 205.138 162.023 1.00 222.49 ? 675 THR H OG1 1 
ATOM 5721 C CG2 . THR C 1 366 ? 165.117 206.473 160.255 1.00 222.49 ? 675 THR H CG2 1 
ATOM 5722 N N   . VAL C 1 367 ? 168.707 205.776 161.325 1.00 183.35 ? 676 VAL H N   1 
ATOM 5723 C CA  . VAL C 1 367 ? 169.632 205.030 160.485 1.00 183.35 ? 676 VAL H CA  1 
ATOM 5724 C C   . VAL C 1 367 ? 168.895 204.327 159.363 1.00 183.35 ? 676 VAL H C   1 
ATOM 5725 O O   . VAL C 1 367 ? 169.491 204.028 158.323 1.00 183.35 ? 676 VAL H O   1 
ATOM 5726 C CB  . VAL C 1 367 ? 170.432 204.013 161.315 1.00 183.35 ? 676 VAL H CB  1 
ATOM 5727 C CG1 . VAL C 1 367 ? 171.246 204.726 162.368 1.00 183.35 ? 676 VAL H CG1 1 
ATOM 5728 C CG2 . VAL C 1 367 ? 169.500 202.993 161.954 1.00 183.35 ? 676 VAL H CG2 1 
ATOM 5729 N N   . LEU C 1 368 ? 167.604 204.051 159.550 1.00 195.04 ? 677 LEU H N   1 
ATOM 5730 C CA  . LEU C 1 368 ? 166.826 203.391 158.510 1.00 195.04 ? 677 LEU H CA  1 
ATOM 5731 C C   . LEU C 1 368 ? 166.729 204.251 157.258 1.00 195.04 ? 677 LEU H C   1 
ATOM 5732 O O   . LEU C 1 368 ? 166.930 203.762 156.141 1.00 195.04 ? 677 LEU H O   1 
ATOM 5733 C CB  . LEU C 1 368 ? 165.427 203.067 159.035 1.00 195.04 ? 677 LEU H CB  1 
ATOM 5734 C CG  . LEU C 1 368 ? 165.240 201.851 159.940 1.00 195.04 ? 677 LEU H CG  1 
ATOM 5735 C CD1 . LEU C 1 368 ? 165.666 202.161 161.354 1.00 195.04 ? 677 LEU H CD1 1 
ATOM 5736 C CD2 . LEU C 1 368 ? 163.791 201.410 159.919 1.00 195.04 ? 677 LEU H CD2 1 
ATOM 5737 N N   . GLN C 1 369 ? 166.444 205.539 157.426 1.00 232.18 ? 678 GLN H N   1 
ATOM 5738 C CA  . GLN C 1 369 ? 166.111 206.395 156.301 1.00 232.18 ? 678 GLN H CA  1 
ATOM 5739 C C   . GLN C 1 369 ? 167.318 207.143 155.756 1.00 232.18 ? 678 GLN H C   1 
ATOM 5740 O O   . GLN C 1 369 ? 167.260 207.656 154.634 1.00 232.18 ? 678 GLN H O   1 
ATOM 5741 C CB  . GLN C 1 369 ? 165.030 207.394 156.727 1.00 232.18 ? 678 GLN H CB  1 
ATOM 5742 C CG  . GLN C 1 369 ? 164.219 208.015 155.603 1.00 232.18 ? 678 GLN H CG  1 
ATOM 5743 C CD  . GLN C 1 369 ? 164.872 209.235 155.008 1.00 232.18 ? 678 GLN H CD  1 
ATOM 5744 O OE1 . GLN C 1 369 ? 165.757 209.831 155.612 1.00 232.18 ? 678 GLN H OE1 1 
ATOM 5745 N NE2 . GLN C 1 369 ? 164.419 209.627 153.825 1.00 232.18 ? 678 GLN H NE2 1 
ATOM 5746 N N   . ASP C 1 370 ? 168.421 207.182 156.502 1.00 226.29 ? 679 ASP H N   1 
ATOM 5747 C CA  . ASP C 1 370 ? 169.575 208.001 156.137 1.00 226.29 ? 679 ASP H CA  1 
ATOM 5748 C C   . ASP C 1 370 ? 170.269 207.379 154.930 1.00 226.29 ? 679 ASP H C   1 
ATOM 5749 O O   . ASP C 1 370 ? 171.259 206.651 155.036 1.00 226.29 ? 679 ASP H O   1 
ATOM 5750 C CB  . ASP C 1 370 ? 170.531 208.138 157.314 1.00 226.29 ? 679 ASP H CB  1 
ATOM 5751 C CG  . ASP C 1 370 ? 170.096 209.201 158.292 1.00 226.29 ? 679 ASP H CG  1 
ATOM 5752 O OD1 . ASP C 1 370 ? 169.391 210.138 157.869 1.00 226.29 ? 679 ASP H OD1 1 
ATOM 5753 O OD2 . ASP C 1 370 ? 170.460 209.100 159.482 1.00 226.29 ? 679 ASP H OD2 1 
ATOM 5754 N N   . CYS C 1 371 ? 169.735 207.692 153.751 1.00 238.50 ? 680 CYS H N   1 
ATOM 5755 C CA  . CYS C 1 371 ? 170.275 207.211 152.491 1.00 238.50 ? 680 CYS H CA  1 
ATOM 5756 C C   . CYS C 1 371 ? 170.870 208.313 151.632 1.00 238.50 ? 680 CYS H C   1 
ATOM 5757 O O   . CYS C 1 371 ? 171.485 208.008 150.604 1.00 238.50 ? 680 CYS H O   1 
ATOM 5758 C CB  . CYS C 1 371 ? 169.183 206.491 151.684 1.00 238.50 ? 680 CYS H CB  1 
ATOM 5759 S SG  . CYS C 1 371 ? 167.946 207.601 150.964 1.00 238.50 ? 680 CYS H SG  1 
ATOM 5760 N N   . LYS C 1 372 ? 170.703 209.576 152.015 1.00 250.21 ? 681 LYS H N   1 
ATOM 5761 C CA  . LYS C 1 372 ? 171.104 210.702 151.181 1.00 250.21 ? 681 LYS H CA  1 
ATOM 5762 C C   . LYS C 1 372 ? 172.467 211.260 151.586 1.00 250.21 ? 681 LYS H C   1 
ATOM 5763 O O   . LYS C 1 372 ? 173.414 211.242 150.793 1.00 250.21 ? 681 LYS H O   1 
ATOM 5764 C CB  . LYS C 1 372 ? 170.015 211.774 151.256 1.00 250.21 ? 681 LYS H CB  1 
ATOM 5765 C CG  . LYS C 1 372 ? 168.711 211.318 150.626 1.00 250.21 ? 681 LYS H CG  1 
ATOM 5766 C CD  . LYS C 1 372 ? 167.653 212.398 150.671 1.00 250.21 ? 681 LYS H CD  1 
ATOM 5767 C CE  . LYS C 1 372 ? 167.005 212.437 152.042 1.00 250.21 ? 681 LYS H CE  1 
ATOM 5768 N NZ  . LYS C 1 372 ? 166.005 211.350 152.188 1.00 250.21 ? 681 LYS H NZ  1 
ATOM 5769 N N   . ARG C 1 373 ? 172.582 211.754 152.821 1.00 236.09 ? 682 ARG H N   1 
ATOM 5770 C CA  . ARG C 1 373 ? 173.860 212.284 153.286 1.00 236.09 ? 682 ARG H CA  1 
ATOM 5771 C C   . ARG C 1 373 ? 174.889 211.177 153.453 1.00 236.09 ? 682 ARG H C   1 
ATOM 5772 O O   . ARG C 1 373 ? 176.064 211.357 153.113 1.00 236.09 ? 682 ARG H O   1 
ATOM 5773 C CB  . ARG C 1 373 ? 173.687 213.026 154.611 1.00 236.09 ? 682 ARG H CB  1 
ATOM 5774 C CG  . ARG C 1 373 ? 174.979 213.108 155.422 1.00 236.09 ? 682 ARG H CG  1 
ATOM 5775 C CD  . ARG C 1 373 ? 174.758 213.646 156.823 1.00 236.09 ? 682 ARG H CD  1 
ATOM 5776 N NE  . ARG C 1 373 ? 174.969 212.619 157.839 1.00 236.09 ? 682 ARG H NE  1 
ATOM 5777 C CZ  . ARG C 1 373 ? 175.845 211.629 157.735 1.00 236.09 ? 682 ARG H CZ  1 
ATOM 5778 N N   . THR C 1 374 ? 174.459 210.022 153.967 1.00 215.57 ? 683 THR H N   1 
ATOM 5779 C CA  . THR C 1 374 ? 175.396 208.987 154.387 1.00 215.57 ? 683 THR H CA  1 
ATOM 5780 C C   . THR C 1 374 ? 176.296 208.536 153.244 1.00 215.57 ? 683 THR H C   1 
ATOM 5781 O O   . THR C 1 374 ? 177.474 208.231 153.468 1.00 215.57 ? 683 THR H O   1 
ATOM 5782 C CB  . THR C 1 374 ? 174.627 207.800 154.969 1.00 215.57 ? 683 THR H CB  1 
ATOM 5783 O OG1 . THR C 1 374 ? 173.648 207.347 154.026 1.00 215.57 ? 683 THR H OG1 1 
ATOM 5784 C CG2 . THR C 1 374 ? 173.930 208.205 156.250 1.00 215.57 ? 683 THR H CG2 1 
ATOM 5785 N N   . LEU C 1 375 ? 175.774 208.522 152.015 1.00 244.91 ? 684 LEU H N   1 
ATOM 5786 C CA  . LEU C 1 375 ? 176.597 208.170 150.863 1.00 244.91 ? 684 LEU H CA  1 
ATOM 5787 C C   . LEU C 1 375 ? 177.746 209.153 150.681 1.00 244.91 ? 684 LEU H C   1 
ATOM 5788 O O   . LEU C 1 375 ? 178.792 208.789 150.133 1.00 244.91 ? 684 LEU H O   1 
ATOM 5789 C CB  . LEU C 1 375 ? 175.731 208.103 149.603 1.00 244.91 ? 684 LEU H CB  1 
ATOM 5790 C CG  . LEU C 1 375 ? 174.910 206.821 149.408 1.00 244.91 ? 684 LEU H CG  1 
ATOM 5791 C CD1 . LEU C 1 375 ? 174.265 206.792 148.034 1.00 244.91 ? 684 LEU H CD1 1 
ATOM 5792 C CD2 . LEU C 1 375 ? 175.761 205.579 149.624 1.00 244.91 ? 684 LEU H CD2 1 
ATOM 5793 N N   . GLU C 1 376 ? 177.575 210.392 151.131 1.00 267.12 ? 685 GLU H N   1 
ATOM 5794 C CA  . GLU C 1 376 ? 178.673 211.349 151.139 1.00 267.12 ? 685 GLU H CA  1 
ATOM 5795 C C   . GLU C 1 376 ? 179.397 211.302 152.477 1.00 267.12 ? 685 GLU H C   1 
ATOM 5796 O O   . GLU C 1 376 ? 178.806 210.955 153.499 1.00 267.12 ? 685 GLU H O   1 
ATOM 5797 C CB  . GLU C 1 376 ? 178.174 212.768 150.862 1.00 267.12 ? 685 GLU H CB  1 
ATOM 5798 C CG  . GLU C 1 376 ? 179.290 213.804 150.823 1.00 267.12 ? 685 GLU H CG  1 
ATOM 5799 C CD  . GLU C 1 376 ? 178.787 215.209 150.555 1.00 267.12 ? 685 GLU H CD  1 
ATOM 5800 O OE1 . GLU C 1 376 ? 177.560 215.387 150.414 1.00 267.12 ? 685 GLU H OE1 1 
ATOM 5801 O OE2 . GLU C 1 376 ? 179.623 216.136 150.487 1.00 267.12 ? 685 GLU H OE2 1 
ATOM 5802 N N   . HIS D 2 10  ? 161.885 192.149 154.622 1.00 146.09 ? 16  HIS I N   1 
ATOM 5803 C CA  . HIS D 2 10  ? 162.120 191.981 156.050 1.00 146.09 ? 16  HIS I CA  1 
ATOM 5804 C C   . HIS D 2 10  ? 163.230 192.895 156.557 1.00 146.09 ? 16  HIS I C   1 
ATOM 5805 O O   . HIS D 2 10  ? 164.017 193.427 155.778 1.00 146.09 ? 16  HIS I O   1 
ATOM 5806 C CB  . HIS D 2 10  ? 162.462 190.522 156.367 1.00 146.09 ? 16  HIS I CB  1 
ATOM 5807 C CG  . HIS D 2 10  ? 162.447 190.204 157.829 1.00 146.09 ? 16  HIS I CG  1 
ATOM 5808 N ND1 . HIS D 2 10  ? 163.599 190.018 158.561 1.00 146.09 ? 16  HIS I ND1 1 
ATOM 5809 C CD2 . HIS D 2 10  ? 161.421 190.061 158.701 1.00 146.09 ? 16  HIS I CD2 1 
ATOM 5810 C CE1 . HIS D 2 10  ? 163.285 189.761 159.818 1.00 146.09 ? 16  HIS I CE1 1 
ATOM 5811 N NE2 . HIS D 2 10  ? 161.969 189.782 159.929 1.00 146.09 ? 16  HIS I NE2 1 
ATOM 5812 N N   . SER D 2 11  ? 163.277 193.082 157.877 1.00 141.12 ? 17  SER I N   1 
ATOM 5813 C CA  . SER D 2 11  ? 164.354 193.854 158.479 1.00 141.12 ? 17  SER I CA  1 
ATOM 5814 C C   . SER D 2 11  ? 165.705 193.175 158.306 1.00 141.12 ? 17  SER I C   1 
ATOM 5815 O O   . SER D 2 11  ? 166.739 193.840 158.407 1.00 141.12 ? 17  SER I O   1 
ATOM 5816 C CB  . SER D 2 11  ? 164.060 194.087 159.958 1.00 141.12 ? 17  SER I CB  1 
ATOM 5817 O OG  . SER D 2 11  ? 162.870 194.838 160.121 1.00 141.12 ? 17  SER I OG  1 
ATOM 5818 N N   . THR D 2 12  ? 165.718 191.862 158.061 1.00 129.32 ? 18  THR I N   1 
ATOM 5819 C CA  . THR D 2 12  ? 166.968 191.189 157.725 1.00 129.32 ? 18  THR I CA  1 
ATOM 5820 C C   . THR D 2 12  ? 167.521 191.697 156.402 1.00 129.32 ? 18  THR I C   1 
ATOM 5821 O O   . THR D 2 12  ? 168.739 191.712 156.204 1.00 129.32 ? 18  THR I O   1 
ATOM 5822 C CB  . THR D 2 12  ? 166.757 189.675 157.673 1.00 129.32 ? 18  THR I CB  1 
ATOM 5823 O OG1 . THR D 2 12  ? 166.120 189.243 158.882 1.00 129.32 ? 18  THR I OG1 1 
ATOM 5824 C CG2 . THR D 2 12  ? 168.090 188.955 157.538 1.00 129.32 ? 18  THR I CG2 1 
ATOM 5825 N N   . ASN D 2 13  ? 166.646 192.119 155.488 1.00 119.20 ? 19  ASN I N   1 
ATOM 5826 C CA  . ASN D 2 13  ? 167.112 192.825 154.300 1.00 119.20 ? 19  ASN I CA  1 
ATOM 5827 C C   . ASN D 2 13  ? 167.825 194.111 154.693 1.00 119.20 ? 19  ASN I C   1 
ATOM 5828 O O   . ASN D 2 13  ? 168.873 194.450 154.128 1.00 119.20 ? 19  ASN I O   1 
ATOM 5829 C CB  . ASN D 2 13  ? 165.933 193.116 153.370 1.00 119.20 ? 19  ASN I CB  1 
ATOM 5830 C CG  . ASN D 2 13  ? 166.362 193.663 152.021 1.00 119.20 ? 19  ASN I CG  1 
ATOM 5831 O OD1 . ASN D 2 13  ? 167.547 193.859 151.759 1.00 119.20 ? 19  ASN I OD1 1 
ATOM 5832 N ND2 . ASN D 2 13  ? 165.387 193.921 151.157 1.00 119.20 ? 19  ASN I ND2 1 
ATOM 5833 N N   . VAL D 2 14  ? 167.282 194.831 155.675 1.00 108.75 ? 20  VAL I N   1 
ATOM 5834 C CA  . VAL D 2 14  ? 167.961 196.018 156.182 1.00 108.75 ? 20  VAL I CA  1 
ATOM 5835 C C   . VAL D 2 14  ? 169.324 195.646 156.739 1.00 108.75 ? 20  VAL I C   1 
ATOM 5836 O O   . VAL D 2 14  ? 170.323 196.323 156.480 1.00 108.75 ? 20  VAL I O   1 
ATOM 5837 C CB  . VAL D 2 14  ? 167.100 196.718 157.246 1.00 108.75 ? 20  VAL I CB  1 
ATOM 5838 C CG1 . VAL D 2 14  ? 167.682 198.078 157.583 1.00 108.75 ? 20  VAL I CG1 1 
ATOM 5839 C CG2 . VAL D 2 14  ? 165.664 196.838 156.771 1.00 108.75 ? 20  VAL I CG2 1 
ATOM 5840 N N   . LEU D 2 15  ? 169.381 194.562 157.513 1.00 103.07 ? 21  LEU I N   1 
ATOM 5841 C CA  . LEU D 2 15  ? 170.643 194.150 158.115 1.00 103.07 ? 21  LEU I CA  1 
ATOM 5842 C C   . LEU D 2 15  ? 171.669 193.782 157.053 1.00 103.07 ? 21  LEU I C   1 
ATOM 5843 O O   . LEU D 2 15  ? 172.839 194.163 157.152 1.00 103.07 ? 21  LEU I O   1 
ATOM 5844 C CB  . LEU D 2 15  ? 170.414 192.974 159.064 1.00 103.07 ? 21  LEU I CB  1 
ATOM 5845 C CG  . LEU D 2 15  ? 170.209 193.333 160.536 1.00 103.07 ? 21  LEU I CG  1 
ATOM 5846 C CD1 . LEU D 2 15  ? 168.839 193.950 160.762 1.00 103.07 ? 21  LEU I CD1 1 
ATOM 5847 C CD2 . LEU D 2 15  ? 170.409 192.117 161.422 1.00 103.07 ? 21  LEU I CD2 1 
ATOM 5848 N N   . LEU D 2 16  ? 171.250 193.040 156.030 1.00 112.23 ? 22  LEU I N   1 
ATOM 5849 C CA  . LEU D 2 16  ? 172.178 192.645 154.979 1.00 112.23 ? 22  LEU I CA  1 
ATOM 5850 C C   . LEU D 2 16  ? 172.646 193.851 154.177 1.00 112.23 ? 22  LEU I C   1 
ATOM 5851 O O   . LEU D 2 16  ? 173.822 193.936 153.802 1.00 112.23 ? 22  LEU I O   1 
ATOM 5852 C CB  . LEU D 2 16  ? 171.529 191.605 154.066 1.00 112.23 ? 22  LEU I CB  1 
ATOM 5853 C CG  . LEU D 2 16  ? 172.497 190.580 153.467 1.00 112.23 ? 22  LEU I CG  1 
ATOM 5854 C CD1 . LEU D 2 16  ? 173.144 189.742 154.559 1.00 112.23 ? 22  LEU I CD1 1 
ATOM 5855 C CD2 . LEU D 2 16  ? 171.798 189.693 152.450 1.00 112.23 ? 22  LEU I CD2 1 
ATOM 5856 N N   . SER D 2 17  ? 171.740 194.789 153.897 1.00 98.15  ? 23  SER I N   1 
ATOM 5857 C CA  . SER D 2 17  ? 172.137 196.005 153.197 1.00 98.15  ? 23  SER I CA  1 
ATOM 5858 C C   . SER D 2 17  ? 173.143 196.803 154.019 1.00 98.15  ? 23  SER I C   1 
ATOM 5859 O O   . SER D 2 17  ? 174.147 197.294 153.487 1.00 98.15  ? 23  SER I O   1 
ATOM 5860 C CB  . SER D 2 17  ? 170.897 196.839 152.879 1.00 98.15  ? 23  SER I CB  1 
ATOM 5861 O OG  . SER D 2 17  ? 170.146 197.103 154.051 1.00 98.15  ? 23  SER I OG  1 
ATOM 5862 N N   . LEU D 2 18  ? 172.899 196.919 155.325 1.00 95.39  ? 24  LEU I N   1 
ATOM 5863 C CA  . LEU D 2 18  ? 173.847 197.604 156.193 1.00 95.39  ? 24  LEU I CA  1 
ATOM 5864 C C   . LEU D 2 18  ? 175.179 196.875 156.216 1.00 95.39  ? 24  LEU I C   1 
ATOM 5865 O O   . LEU D 2 18  ? 176.239 197.504 156.244 1.00 95.39  ? 24  LEU I O   1 
ATOM 5866 C CB  . LEU D 2 18  ? 173.276 197.722 157.604 1.00 95.39  ? 24  LEU I CB  1 
ATOM 5867 C CG  . LEU D 2 18  ? 172.070 198.652 157.762 1.00 95.39  ? 24  LEU I CG  1 
ATOM 5868 C CD1 . LEU D 2 18  ? 171.587 198.688 159.203 1.00 95.39  ? 24  LEU I CD1 1 
ATOM 5869 C CD2 . LEU D 2 18  ? 172.383 200.052 157.252 1.00 95.39  ? 24  LEU I CD2 1 
ATOM 5870 N N   . ASN D 2 19  ? 175.143 195.543 156.203 1.00 100.64 ? 25  ASN I N   1 
ATOM 5871 C CA  . ASN D 2 19  ? 176.371 194.760 156.206 1.00 100.64 ? 25  ASN I CA  1 
ATOM 5872 C C   . ASN D 2 19  ? 177.187 195.020 154.949 1.00 100.64 ? 25  ASN I C   1 
ATOM 5873 O O   . ASN D 2 19  ? 178.406 195.223 155.009 1.00 100.64 ? 25  ASN I O   1 
ATOM 5874 C CB  . ASN D 2 19  ? 176.029 193.275 156.323 1.00 100.64 ? 25  ASN I CB  1 
ATOM 5875 C CG  . ASN D 2 19  ? 177.249 192.411 156.537 1.00 100.64 ? 25  ASN I CG  1 
ATOM 5876 O OD1 . ASN D 2 19  ? 178.376 192.902 156.577 1.00 100.64 ? 25  ASN I OD1 1 
ATOM 5877 N ND2 . ASN D 2 19  ? 177.032 191.112 156.667 1.00 100.64 ? 25  ASN I ND2 1 
ATOM 5878 N N   . ASP D 2 20  ? 176.526 195.014 153.794 1.00 116.14 ? 26  ASP I N   1 
ATOM 5879 C CA  . ASP D 2 20  ? 177.251 195.253 152.554 1.00 116.14 ? 26  ASP I CA  1 
ATOM 5880 C C   . ASP D 2 20  ? 177.799 196.671 152.518 1.00 116.14 ? 26  ASP I C   1 
ATOM 5881 O O   . ASP D 2 20  ? 178.920 196.901 152.050 1.00 116.14 ? 26  ASP I O   1 
ATOM 5882 C CB  . ASP D 2 20  ? 176.363 194.979 151.344 1.00 116.14 ? 26  ASP I CB  1 
ATOM 5883 C CG  . ASP D 2 20  ? 177.150 194.949 150.047 1.00 116.14 ? 26  ASP I CG  1 
ATOM 5884 O OD1 . ASP D 2 20  ? 177.686 196.001 149.644 1.00 116.14 ? 26  ASP I OD1 1 
ATOM 5885 O OD2 . ASP D 2 20  ? 177.249 193.863 149.439 1.00 116.14 ? 26  ASP I OD2 1 
ATOM 5886 N N   . GLN D 2 21  ? 177.026 197.638 153.017 1.00 111.69 ? 27  GLN I N   1 
ATOM 5887 C CA  . GLN D 2 21  ? 177.542 198.998 153.097 1.00 111.69 ? 27  GLN I CA  1 
ATOM 5888 C C   . GLN D 2 21  ? 178.741 199.079 154.025 1.00 111.69 ? 27  GLN I C   1 
ATOM 5889 O O   . GLN D 2 21  ? 179.696 199.813 153.747 1.00 111.69 ? 27  GLN I O   1 
ATOM 5890 C CB  . GLN D 2 21  ? 176.452 199.956 153.560 1.00 111.69 ? 27  GLN I CB  1 
ATOM 5891 C CG  . GLN D 2 21  ? 176.852 201.393 153.384 1.00 111.69 ? 27  GLN I CG  1 
ATOM 5892 C CD  . GLN D 2 21  ? 176.672 201.865 151.962 1.00 111.69 ? 27  GLN I CD  1 
ATOM 5893 O OE1 . GLN D 2 21  ? 177.589 202.423 151.365 1.00 111.69 ? 27  GLN I OE1 1 
ATOM 5894 N NE2 . GLN D 2 21  ? 175.485 201.648 151.411 1.00 111.69 ? 27  GLN I NE2 1 
ATOM 5895 N N   . ARG D 2 22  ? 178.708 198.336 155.130 1.00 87.59  ? 28  ARG I N   1 
ATOM 5896 C CA  . ARG D 2 22  ? 179.843 198.306 156.039 1.00 87.59  ? 28  ARG I CA  1 
ATOM 5897 C C   . ARG D 2 22  ? 181.071 197.753 155.339 1.00 87.59  ? 28  ARG I C   1 
ATOM 5898 O O   . ARG D 2 22  ? 182.179 198.277 155.496 1.00 87.59  ? 28  ARG I O   1 
ATOM 5899 C CB  . ARG D 2 22  ? 179.511 197.461 157.266 1.00 87.59  ? 28  ARG I CB  1 
ATOM 5900 C CG  . ARG D 2 22  ? 180.653 196.576 157.740 1.00 87.59  ? 28  ARG I CG  1 
ATOM 5901 C CD  . ARG D 2 22  ? 180.188 195.569 158.765 1.00 87.59  ? 28  ARG I CD  1 
ATOM 5902 N NE  . ARG D 2 22  ? 180.940 194.326 158.690 1.00 87.59  ? 28  ARG I NE  1 
ATOM 5903 C CZ  . ARG D 2 22  ? 182.248 194.255 158.484 1.00 87.59  ? 28  ARG I CZ  1 
ATOM 5904 N N   . LYS D 2 23  ? 180.886 196.706 154.544 1.00 94.41  ? 29  LYS I N   1 
ATOM 5905 C CA  . LYS D 2 23  ? 182.017 196.079 153.877 1.00 94.41  ? 29  LYS I CA  1 
ATOM 5906 C C   . LYS D 2 23  ? 182.365 196.834 152.598 1.00 94.41  ? 29  LYS I C   1 
ATOM 5907 O O   . LYS D 2 23  ? 182.571 196.243 151.533 1.00 94.41  ? 29  LYS I O   1 
ATOM 5908 C CB  . LYS D 2 23  ? 181.704 194.599 153.637 1.00 94.41  ? 29  LYS I CB  1 
ATOM 5909 C CG  . LYS D 2 23  ? 180.557 194.331 152.694 1.00 94.41  ? 29  LYS I CG  1 
ATOM 5910 C CD  . LYS D 2 23  ? 180.337 192.849 152.519 1.00 94.41  ? 29  LYS I CD  1 
ATOM 5911 C CE  . LYS D 2 23  ? 179.708 192.269 153.775 1.00 94.41  ? 29  LYS I CE  1 
ATOM 5912 N NZ  . LYS D 2 23  ? 179.345 190.838 153.620 1.00 94.41  ? 29  LYS I NZ  1 
ATOM 5913 N N   . LYS D 2 24  ? 182.460 198.162 152.722 1.00 109.67 ? 30  LYS I N   1 
ATOM 5914 C CA  . LYS D 2 24  ? 183.042 199.027 151.707 1.00 109.67 ? 30  LYS I CA  1 
ATOM 5915 C C   . LYS D 2 24  ? 183.904 200.122 152.318 1.00 109.67 ? 30  LYS I C   1 
ATOM 5916 O O   . LYS D 2 24  ? 184.504 200.898 151.567 1.00 109.67 ? 30  LYS I O   1 
ATOM 5917 C CB  . LYS D 2 24  ? 181.952 199.685 150.842 1.00 109.67 ? 30  LYS I CB  1 
ATOM 5918 C CG  . LYS D 2 24  ? 180.906 198.752 150.268 1.00 109.67 ? 30  LYS I CG  1 
ATOM 5919 C CD  . LYS D 2 24  ? 181.344 198.207 148.926 1.00 109.67 ? 30  LYS I CD  1 
ATOM 5920 C CE  . LYS D 2 24  ? 180.344 197.198 148.398 1.00 109.67 ? 30  LYS I CE  1 
ATOM 5921 N NZ  . LYS D 2 24  ? 178.947 197.624 148.684 1.00 109.67 ? 30  LYS I NZ  1 
ATOM 5922 N N   . ASP D 2 25  ? 183.985 200.203 153.648 1.00 118.33 ? 31  ASP I N   1 
ATOM 5923 C CA  . ASP D 2 25  ? 184.634 201.308 154.354 1.00 118.33 ? 31  ASP I CA  1 
ATOM 5924 C C   . ASP D 2 25  ? 183.996 202.645 153.974 1.00 118.33 ? 31  ASP I C   1 
ATOM 5925 O O   . ASP D 2 25  ? 184.681 203.615 153.652 1.00 118.33 ? 31  ASP I O   1 
ATOM 5926 C CB  . ASP D 2 25  ? 186.146 201.319 154.103 1.00 118.33 ? 31  ASP I CB  1 
ATOM 5927 C CG  . ASP D 2 25  ? 186.886 202.313 154.986 1.00 118.33 ? 31  ASP I CG  1 
ATOM 5928 O OD1 . ASP D 2 25  ? 186.236 203.024 155.781 1.00 118.33 ? 31  ASP I OD1 1 
ATOM 5929 O OD2 . ASP D 2 25  ? 188.128 202.380 154.890 1.00 118.33 ? 31  ASP I OD2 1 
ATOM 5930 N N   . VAL D 2 26  ? 182.665 202.689 153.991 1.00 112.58 ? 32  VAL I N   1 
ATOM 5931 C CA  . VAL D 2 26  ? 181.925 203.929 153.790 1.00 112.58 ? 32  VAL I CA  1 
ATOM 5932 C C   . VAL D 2 26  ? 180.573 203.790 154.473 1.00 112.58 ? 32  VAL I C   1 
ATOM 5933 O O   . VAL D 2 26  ? 180.023 202.690 154.581 1.00 112.58 ? 32  VAL I O   1 
ATOM 5934 C CB  . VAL D 2 26  ? 181.768 204.274 152.291 1.00 112.58 ? 32  VAL I CB  1 
ATOM 5935 C CG1 . VAL D 2 26  ? 180.704 203.407 151.649 1.00 112.58 ? 32  VAL I CG1 1 
ATOM 5936 C CG2 . VAL D 2 26  ? 181.441 205.747 152.120 1.00 112.58 ? 32  VAL I CG2 1 
ATOM 5937 N N   . LEU D 2 27  ? 180.041 204.925 154.936 1.00 111.00 ? 33  LEU I N   1 
ATOM 5938 C CA  . LEU D 2 27  ? 178.831 204.977 155.762 1.00 111.00 ? 33  LEU I CA  1 
ATOM 5939 C C   . LEU D 2 27  ? 179.042 204.301 157.114 1.00 111.00 ? 33  LEU I C   1 
ATOM 5940 O O   . LEU D 2 27  ? 178.082 203.937 157.794 1.00 111.00 ? 33  LEU I O   1 
ATOM 5941 C CB  . LEU D 2 27  ? 177.631 204.354 155.044 1.00 111.00 ? 33  LEU I CB  1 
ATOM 5942 C CG  . LEU D 2 27  ? 176.904 205.192 154.000 1.00 111.00 ? 33  LEU I CG  1 
ATOM 5943 C CD1 . LEU D 2 27  ? 177.697 205.218 152.713 1.00 111.00 ? 33  LEU I CD1 1 
ATOM 5944 C CD2 . LEU D 2 27  ? 175.510 204.645 153.752 1.00 111.00 ? 33  LEU I CD2 1 
ATOM 5945 N N   . CYS D 2 28  ? 180.298 204.150 157.519 1.00 106.22 ? 34  CYS I N   1 
ATOM 5946 C CA  . CYS D 2 28  ? 180.646 203.534 158.788 1.00 106.22 ? 34  CYS I CA  1 
ATOM 5947 C C   . CYS D 2 28  ? 180.787 204.617 159.844 1.00 106.22 ? 34  CYS I C   1 
ATOM 5948 O O   . CYS D 2 28  ? 181.433 205.645 159.616 1.00 106.22 ? 34  CYS I O   1 
ATOM 5949 C CB  . CYS D 2 28  ? 181.943 202.735 158.682 1.00 106.22 ? 34  CYS I CB  1 
ATOM 5950 S SG  . CYS D 2 28  ? 183.351 203.679 158.058 1.00 106.22 ? 34  CYS I SG  1 
ATOM 5951 N N   . ASP D 2 29  ? 180.191 204.378 161.006 1.00 98.87  ? 35  ASP I N   1 
ATOM 5952 C CA  . ASP D 2 29  ? 179.990 205.418 162.000 1.00 98.87  ? 35  ASP I CA  1 
ATOM 5953 C C   . ASP D 2 29  ? 180.843 205.219 163.243 1.00 98.87  ? 35  ASP I C   1 
ATOM 5954 O O   . ASP D 2 29  ? 181.420 206.179 163.757 1.00 98.87  ? 35  ASP I O   1 
ATOM 5955 C CB  . ASP D 2 29  ? 178.500 205.464 162.366 1.00 98.87  ? 35  ASP I CB  1 
ATOM 5956 C CG  . ASP D 2 29  ? 178.103 206.753 163.029 1.00 98.87  ? 35  ASP I CG  1 
ATOM 5957 O OD1 . ASP D 2 29  ? 178.977 207.624 163.209 1.00 98.87  ? 35  ASP I OD1 1 
ATOM 5958 O OD2 . ASP D 2 29  ? 176.906 206.909 163.340 1.00 98.87  ? 35  ASP I OD2 1 
ATOM 5959 N N   . VAL D 2 30  ? 180.951 203.987 163.732 1.00 90.66  ? 36  VAL I N   1 
ATOM 5960 C CA  . VAL D 2 30  ? 181.693 203.665 164.946 1.00 90.66  ? 36  VAL I CA  1 
ATOM 5961 C C   . VAL D 2 30  ? 182.909 202.834 164.569 1.00 90.66  ? 36  VAL I C   1 
ATOM 5962 O O   . VAL D 2 30  ? 182.786 201.827 163.864 1.00 90.66  ? 36  VAL I O   1 
ATOM 5963 C CB  . VAL D 2 30  ? 180.804 202.912 165.949 1.00 90.66  ? 36  VAL I CB  1 
ATOM 5964 C CG1 . VAL D 2 30  ? 181.624 202.370 167.093 1.00 90.66  ? 36  VAL I CG1 1 
ATOM 5965 C CG2 . VAL D 2 30  ? 179.704 203.819 166.458 1.00 90.66  ? 36  VAL I CG2 1 
ATOM 5966 N N   . THR D 2 31  ? 184.078 203.237 165.046 1.00 105.71 ? 37  THR I N   1 
ATOM 5967 C CA  . THR D 2 31  ? 185.324 202.583 164.675 1.00 105.71 ? 37  THR I CA  1 
ATOM 5968 C C   . THR D 2 31  ? 185.947 201.909 165.889 1.00 105.71 ? 37  THR I C   1 
ATOM 5969 O O   . THR D 2 31  ? 186.180 202.560 166.912 1.00 105.71 ? 37  THR I O   1 
ATOM 5970 C CB  . THR D 2 31  ? 186.296 203.594 164.073 1.00 105.71 ? 37  THR I CB  1 
ATOM 5971 O OG1 . THR D 2 31  ? 185.616 204.356 163.069 1.00 105.71 ? 37  THR I OG1 1 
ATOM 5972 C CG2 . THR D 2 31  ? 187.461 202.876 163.431 1.00 105.71 ? 37  THR I CG2 1 
ATOM 5973 N N   . ILE D 2 32  ? 186.240 200.613 165.765 1.00 114.82 ? 38  ILE I N   1 
ATOM 5974 C CA  . ILE D 2 32  ? 186.822 199.811 166.835 1.00 114.82 ? 38  ILE I CA  1 
ATOM 5975 C C   . ILE D 2 32  ? 188.318 199.707 166.591 1.00 114.82 ? 38  ILE I C   1 
ATOM 5976 O O   . ILE D 2 32  ? 188.751 199.513 165.449 1.00 114.82 ? 38  ILE I O   1 
ATOM 5977 C CB  . ILE D 2 32  ? 186.190 198.413 166.886 1.00 114.82 ? 38  ILE I CB  1 
ATOM 5978 C CG1 . ILE D 2 32  ? 184.667 198.512 166.867 1.00 114.82 ? 38  ILE I CG1 1 
ATOM 5979 C CG2 . ILE D 2 32  ? 186.668 197.670 168.117 1.00 114.82 ? 38  ILE I CG2 1 
ATOM 5980 C CD1 . ILE D 2 32  ? 184.100 199.202 168.054 1.00 114.82 ? 38  ILE I CD1 1 
ATOM 5981 N N   . PHE D 2 33  ? 189.114 199.840 167.647 1.00 126.91 ? 39  PHE I N   1 
ATOM 5982 C CA  . PHE D 2 33  ? 190.565 199.818 167.521 1.00 126.91 ? 39  PHE I CA  1 
ATOM 5983 C C   . PHE D 2 33  ? 191.141 198.714 168.394 1.00 126.91 ? 39  PHE I C   1 
ATOM 5984 O O   . PHE D 2 33  ? 190.947 198.719 169.614 1.00 126.91 ? 39  PHE I O   1 
ATOM 5985 C CB  . PHE D 2 33  ? 191.146 201.173 167.908 1.00 126.91 ? 39  PHE I CB  1 
ATOM 5986 C CG  . PHE D 2 33  ? 190.909 202.225 166.880 1.00 126.91 ? 39  PHE I CG  1 
ATOM 5987 C CD1 . PHE D 2 33  ? 189.713 202.917 166.865 1.00 126.91 ? 39  PHE I CD1 1 
ATOM 5988 C CD2 . PHE D 2 33  ? 191.856 202.509 165.913 1.00 126.91 ? 39  PHE I CD2 1 
ATOM 5989 C CE1 . PHE D 2 33  ? 189.474 203.885 165.925 1.00 126.91 ? 39  PHE I CE1 1 
ATOM 5990 C CE2 . PHE D 2 33  ? 191.617 203.479 164.960 1.00 126.91 ? 39  PHE I CE2 1 
ATOM 5991 C CZ  . PHE D 2 33  ? 190.424 204.166 164.966 1.00 126.91 ? 39  PHE I CZ  1 
ATOM 5992 N N   . VAL D 2 34  ? 191.869 197.784 167.774 1.00 134.11 ? 40  VAL I N   1 
ATOM 5993 C CA  . VAL D 2 34  ? 192.492 196.659 168.471 1.00 134.11 ? 40  VAL I CA  1 
ATOM 5994 C C   . VAL D 2 34  ? 193.971 196.623 168.086 1.00 134.11 ? 40  VAL I C   1 
ATOM 5995 O O   . VAL D 2 34  ? 194.326 196.221 166.972 1.00 134.11 ? 40  VAL I O   1 
ATOM 5996 C CB  . VAL D 2 34  ? 191.792 195.326 168.174 1.00 134.11 ? 40  VAL I CB  1 
ATOM 5997 C CG1 . VAL D 2 34  ? 190.456 195.265 168.897 1.00 134.11 ? 40  VAL I CG1 1 
ATOM 5998 C CG2 . VAL D 2 34  ? 191.551 195.163 166.686 1.00 134.11 ? 40  VAL I CG2 1 
ATOM 5999 N N   . GLU D 2 35  ? 194.833 197.066 169.008 1.00 134.06 ? 41  GLU I N   1 
ATOM 6000 C CA  . GLU D 2 35  ? 196.293 197.158 168.890 1.00 134.06 ? 41  GLU I CA  1 
ATOM 6001 C C   . GLU D 2 35  ? 196.746 197.718 167.542 1.00 134.06 ? 41  GLU I C   1 
ATOM 6002 O O   . GLU D 2 35  ? 197.878 197.481 167.111 1.00 134.06 ? 41  GLU I O   1 
ATOM 6003 C CB  . GLU D 2 35  ? 196.944 195.792 169.199 1.00 134.06 ? 41  GLU I CB  1 
ATOM 6004 C CG  . GLU D 2 35  ? 196.597 194.595 168.302 1.00 134.06 ? 41  GLU I CG  1 
ATOM 6005 C CD  . GLU D 2 35  ? 197.465 194.471 167.056 1.00 134.06 ? 41  GLU I CD  1 
ATOM 6006 O OE1 . GLU D 2 35  ? 198.572 195.046 167.025 1.00 134.06 ? 41  GLU I OE1 1 
ATOM 6007 O OE2 . GLU D 2 35  ? 197.034 193.788 166.103 1.00 134.06 ? 41  GLU I OE2 1 
ATOM 6008 N N   . GLY D 2 36  ? 195.907 198.546 166.919 1.00 146.58 ? 42  GLY I N   1 
ATOM 6009 C CA  . GLY D 2 36  ? 196.236 199.155 165.643 1.00 146.58 ? 42  GLY I CA  1 
ATOM 6010 C C   . GLY D 2 36  ? 195.237 198.874 164.539 1.00 146.58 ? 42  GLY I C   1 
ATOM 6011 O O   . GLY D 2 36  ? 194.947 199.752 163.721 1.00 146.58 ? 42  GLY I O   1 
ATOM 6012 N N   . GLN D 2 37  ? 194.714 197.652 164.495 1.00 144.02 ? 43  GLN I N   1 
ATOM 6013 C CA  . GLN D 2 37  ? 193.672 197.326 163.533 1.00 144.02 ? 43  GLN I CA  1 
ATOM 6014 C C   . GLN D 2 37  ? 192.437 198.173 163.787 1.00 144.02 ? 43  GLN I C   1 
ATOM 6015 O O   . GLN D 2 37  ? 191.969 198.287 164.922 1.00 144.02 ? 43  GLN I O   1 
ATOM 6016 C CB  . GLN D 2 37  ? 193.294 195.851 163.628 1.00 144.02 ? 43  GLN I CB  1 
ATOM 6017 C CG  . GLN D 2 37  ? 192.470 195.354 162.454 1.00 144.02 ? 43  GLN I CG  1 
ATOM 6018 C CD  . GLN D 2 37  ? 190.984 195.593 162.641 1.00 144.02 ? 43  GLN I CD  1 
ATOM 6019 O OE1 . GLN D 2 37  ? 190.513 195.824 163.753 1.00 144.02 ? 43  GLN I OE1 1 
ATOM 6020 N NE2 . GLN D 2 37  ? 190.237 195.540 161.549 1.00 144.02 ? 43  GLN I NE2 1 
ATOM 6021 N N   . ARG D 2 38  ? 191.894 198.753 162.722 1.00 126.47 ? 44  ARG I N   1 
ATOM 6022 C CA  . ARG D 2 38  ? 190.640 199.488 162.793 1.00 126.47 ? 44  ARG I CA  1 
ATOM 6023 C C   . ARG D 2 38  ? 189.560 198.694 162.079 1.00 126.47 ? 44  ARG I C   1 
ATOM 6024 O O   . ARG D 2 38  ? 189.701 198.361 160.900 1.00 126.47 ? 44  ARG I O   1 
ATOM 6025 C CB  . ARG D 2 38  ? 190.760 200.885 162.178 1.00 126.47 ? 44  ARG I CB  1 
ATOM 6026 C CG  . ARG D 2 38  ? 192.009 201.132 161.357 1.00 126.47 ? 44  ARG I CG  1 
ATOM 6027 C CD  . ARG D 2 38  ? 191.826 202.356 160.476 1.00 126.47 ? 44  ARG I CD  1 
ATOM 6028 N NE  . ARG D 2 38  ? 191.995 203.595 161.224 1.00 126.47 ? 44  ARG I NE  1 
ATOM 6029 C CZ  . ARG D 2 38  ? 193.108 203.942 161.856 1.00 126.47 ? 44  ARG I CZ  1 
ATOM 6030 N N   . PHE D 2 39  ? 188.487 198.401 162.796 1.00 111.48 ? 45  PHE I N   1 
ATOM 6031 C CA  . PHE D 2 39  ? 187.344 197.694 162.249 1.00 111.48 ? 45  PHE I CA  1 
ATOM 6032 C C   . PHE D 2 39  ? 186.158 198.643 162.296 1.00 111.48 ? 45  PHE I C   1 
ATOM 6033 O O   . PHE D 2 39  ? 185.719 199.036 163.382 1.00 111.48 ? 45  PHE I O   1 
ATOM 6034 C CB  . PHE D 2 39  ? 187.066 196.418 163.041 1.00 111.48 ? 45  PHE I CB  1 
ATOM 6035 C CG  . PHE D 2 39  ? 186.005 195.557 162.441 1.00 111.48 ? 45  PHE I CG  1 
ATOM 6036 C CD1 . PHE D 2 39  ? 186.228 194.907 161.243 1.00 111.48 ? 45  PHE I CD1 1 
ATOM 6037 C CD2 . PHE D 2 39  ? 184.789 195.398 163.066 1.00 111.48 ? 45  PHE I CD2 1 
ATOM 6038 C CE1 . PHE D 2 39  ? 185.256 194.113 160.683 1.00 111.48 ? 45  PHE I CE1 1 
ATOM 6039 C CE2 . PHE D 2 39  ? 183.816 194.607 162.509 1.00 111.48 ? 45  PHE I CE2 1 
ATOM 6040 C CZ  . PHE D 2 39  ? 184.049 193.963 161.316 1.00 111.48 ? 45  PHE I CZ  1 
ATOM 6041 N N   . ARG D 2 40  ? 185.655 199.025 161.131 1.00 84.98  ? 46  ARG I N   1 
ATOM 6042 C CA  . ARG D 2 40  ? 184.610 200.030 161.035 1.00 84.98  ? 46  ARG I CA  1 
ATOM 6043 C C   . ARG D 2 40  ? 183.248 199.364 161.063 1.00 84.98  ? 46  ARG I C   1 
ATOM 6044 O O   . ARG D 2 40  ? 183.088 198.237 160.591 1.00 84.98  ? 46  ARG I O   1 
ATOM 6045 C CB  . ARG D 2 40  ? 184.757 200.856 159.759 1.00 84.98  ? 46  ARG I CB  1 
ATOM 6046 C CG  . ARG D 2 40  ? 186.195 201.113 159.337 1.00 84.98  ? 46  ARG I CG  1 
ATOM 6047 C CD  . ARG D 2 40  ? 186.777 202.331 160.036 1.00 84.98  ? 46  ARG I CD  1 
ATOM 6048 N NE  . ARG D 2 40  ? 186.342 203.579 159.420 1.00 84.98  ? 46  ARG I NE  1 
ATOM 6049 C CZ  . ARG D 2 40  ? 186.007 204.668 160.096 1.00 84.98  ? 46  ARG I CZ  1 
ATOM 6050 N N   . ALA D 2 41  ? 182.272 200.058 161.629 1.00 82.98  ? 47  ALA I N   1 
ATOM 6051 C CA  . ALA D 2 41  ? 180.912 199.560 161.694 1.00 82.98  ? 47  ALA I CA  1 
ATOM 6052 C C   . ALA D 2 41  ? 180.000 200.746 161.958 1.00 82.98  ? 47  ALA I C   1 
ATOM 6053 O O   . ALA D 2 41  ? 180.401 201.902 161.801 1.00 82.98  ? 47  ALA I O   1 
ATOM 6054 C CB  . ALA D 2 41  ? 180.779 198.474 162.761 1.00 82.98  ? 47  ALA I CB  1 
ATOM 6055 N N   . HIS D 2 42  ? 178.775 200.468 162.361 1.00 96.83  ? 48  HIS I N   1 
ATOM 6056 C CA  . HIS D 2 42  ? 177.779 201.512 162.490 1.00 96.83  ? 48  HIS I CA  1 
ATOM 6057 C C   . HIS D 2 42  ? 177.598 201.910 163.950 1.00 96.83  ? 48  HIS I C   1 
ATOM 6058 O O   . HIS D 2 42  ? 178.340 201.480 164.832 1.00 96.83  ? 48  HIS I O   1 
ATOM 6059 C CB  . HIS D 2 42  ? 176.482 201.042 161.848 1.00 96.83  ? 48  HIS I CB  1 
ATOM 6060 C CG  . HIS D 2 42  ? 176.591 200.876 160.368 1.00 96.83  ? 48  HIS I CG  1 
ATOM 6061 N ND1 . HIS D 2 42  ? 177.538 201.540 159.618 1.00 96.83  ? 48  HIS I ND1 1 
ATOM 6062 C CD2 . HIS D 2 42  ? 175.887 200.116 159.499 1.00 96.83  ? 48  HIS I CD2 1 
ATOM 6063 C CE1 . HIS D 2 42  ? 177.408 201.199 158.350 1.00 96.83  ? 48  HIS I CE1 1 
ATOM 6064 N NE2 . HIS D 2 42  ? 176.414 200.336 158.250 1.00 96.83  ? 48  HIS I NE2 1 
ATOM 6065 N N   . ARG D 2 43  ? 176.589 202.741 164.210 1.00 86.90  ? 49  ARG I N   1 
ATOM 6066 C CA  . ARG D 2 43  ? 176.300 203.260 165.541 1.00 86.90  ? 49  ARG I CA  1 
ATOM 6067 C C   . ARG D 2 43  ? 175.183 202.507 166.247 1.00 86.90  ? 49  ARG I C   1 
ATOM 6068 O O   . ARG D 2 43  ? 175.289 202.240 167.445 1.00 86.90  ? 49  ARG I O   1 
ATOM 6069 C CB  . ARG D 2 43  ? 175.931 204.745 165.457 1.00 86.90  ? 49  ARG I CB  1 
ATOM 6070 C CG  . ARG D 2 43  ? 176.432 205.592 166.620 1.00 86.90  ? 49  ARG I CG  1 
ATOM 6071 C CD  . ARG D 2 43  ? 175.338 206.511 167.149 1.00 86.90  ? 49  ARG I CD  1 
ATOM 6072 N NE  . ARG D 2 43  ? 175.796 207.886 167.310 1.00 86.90  ? 49  ARG I NE  1 
ATOM 6073 C CZ  . ARG D 2 43  ? 176.928 208.236 167.902 1.00 86.90  ? 49  ARG I CZ  1 
ATOM 6074 N N   . SER D 2 44  ? 174.106 202.172 165.540 1.00 90.02  ? 50  SER I N   1 
ATOM 6075 C CA  . SER D 2 44  ? 172.976 201.521 166.189 1.00 90.02  ? 50  SER I CA  1 
ATOM 6076 C C   . SER D 2 44  ? 173.259 200.057 166.504 1.00 90.02  ? 50  SER I C   1 
ATOM 6077 O O   . SER D 2 44  ? 172.898 199.566 167.582 1.00 90.02  ? 50  SER I O   1 
ATOM 6078 C CB  . SER D 2 44  ? 171.738 201.636 165.305 1.00 90.02  ? 50  SER I CB  1 
ATOM 6079 O OG  . SER D 2 44  ? 171.186 202.935 165.374 1.00 90.02  ? 50  SER I OG  1 
ATOM 6080 N N   . VAL D 2 45  ? 173.899 199.343 165.580 1.00 112.45 ? 51  VAL I N   1 
ATOM 6081 C CA  . VAL D 2 45  ? 173.946 197.888 165.676 1.00 112.45 ? 51  VAL I CA  1 
ATOM 6082 C C   . VAL D 2 45  ? 174.849 197.436 166.820 1.00 112.45 ? 51  VAL I C   1 
ATOM 6083 O O   . VAL D 2 45  ? 174.485 196.547 167.596 1.00 112.45 ? 51  VAL I O   1 
ATOM 6084 C CB  . VAL D 2 45  ? 174.367 197.278 164.332 1.00 112.45 ? 51  VAL I CB  1 
ATOM 6085 C CG1 . VAL D 2 45  ? 174.759 195.837 164.513 1.00 112.45 ? 51  VAL I CG1 1 
ATOM 6086 C CG2 . VAL D 2 45  ? 173.215 197.375 163.359 1.00 112.45 ? 51  VAL I CG2 1 
ATOM 6087 N N   . LEU D 2 46  ? 176.040 198.025 166.945 1.00 140.46 ? 52  LEU I N   1 
ATOM 6088 C CA  . LEU D 2 46  ? 176.885 197.660 168.079 1.00 140.46 ? 52  LEU I CA  1 
ATOM 6089 C C   . LEU D 2 46  ? 176.234 198.028 169.400 1.00 140.46 ? 52  LEU I C   1 
ATOM 6090 O O   . LEU D 2 46  ? 176.493 197.381 170.418 1.00 140.46 ? 52  LEU I O   1 
ATOM 6091 C CB  . LEU D 2 46  ? 178.265 198.303 167.965 1.00 140.46 ? 52  LEU I CB  1 
ATOM 6092 C CG  . LEU D 2 46  ? 179.269 197.603 167.057 1.00 140.46 ? 52  LEU I CG  1 
ATOM 6093 C CD1 . LEU D 2 46  ? 178.905 197.775 165.615 1.00 140.46 ? 52  LEU I CD1 1 
ATOM 6094 C CD2 . LEU D 2 46  ? 180.658 198.151 167.313 1.00 140.46 ? 52  LEU I CD2 1 
ATOM 6095 N N   . ALA D 2 47  ? 175.392 199.060 169.410 1.00 106.71 ? 53  ALA I N   1 
ATOM 6096 C CA  . ALA D 2 47  ? 174.603 199.336 170.603 1.00 106.71 ? 53  ALA I CA  1 
ATOM 6097 C C   . ALA D 2 47  ? 173.632 198.201 170.882 1.00 106.71 ? 53  ALA I C   1 
ATOM 6098 O O   . ALA D 2 47  ? 173.408 197.836 172.041 1.00 106.71 ? 53  ALA I O   1 
ATOM 6099 C CB  . ALA D 2 47  ? 173.853 200.657 170.453 1.00 106.71 ? 53  ALA I CB  1 
ATOM 6100 N N   . ALA D 2 48  ? 173.042 197.633 169.833 1.00 103.90 ? 54  ALA I N   1 
ATOM 6101 C CA  . ALA D 2 48  ? 172.119 196.526 170.045 1.00 103.90 ? 54  ALA I CA  1 
ATOM 6102 C C   . ALA D 2 48  ? 172.829 195.231 170.417 1.00 103.90 ? 54  ALA I C   1 
ATOM 6103 O O   . ALA D 2 48  ? 172.215 194.359 171.037 1.00 103.90 ? 54  ALA I O   1 
ATOM 6104 C CB  . ALA D 2 48  ? 171.274 196.293 168.796 1.00 103.90 ? 54  ALA I CB  1 
ATOM 6105 N N   . CYS D 2 49  ? 174.097 195.079 170.042 1.00 108.45 ? 55  CYS I N   1 
ATOM 6106 C CA  . CYS D 2 49  ? 174.760 193.788 170.194 1.00 108.45 ? 55  CYS I CA  1 
ATOM 6107 C C   . CYS D 2 49  ? 175.388 193.611 171.573 1.00 108.45 ? 55  CYS I C   1 
ATOM 6108 O O   . CYS D 2 49  ? 174.936 192.784 172.371 1.00 108.45 ? 55  CYS I O   1 
ATOM 6109 C CB  . CYS D 2 49  ? 175.824 193.623 169.107 1.00 108.45 ? 55  CYS I CB  1 
ATOM 6110 S SG  . CYS D 2 49  ? 176.820 192.132 169.269 1.00 108.45 ? 55  CYS I SG  1 
ATOM 6111 N N   . SER D 2 50  ? 176.419 194.394 171.880 1.00 88.84  ? 56  SER I N   1 
ATOM 6112 C CA  . SER D 2 50  ? 177.279 194.135 173.025 1.00 88.84  ? 56  SER I CA  1 
ATOM 6113 C C   . SER D 2 50  ? 177.083 195.222 174.067 1.00 88.84  ? 56  SER I C   1 
ATOM 6114 O O   . SER D 2 50  ? 177.340 196.400 173.803 1.00 88.84  ? 56  SER I O   1 
ATOM 6115 C CB  . SER D 2 50  ? 178.747 194.069 172.599 1.00 88.84  ? 56  SER I CB  1 
ATOM 6116 O OG  . SER D 2 50  ? 178.958 193.065 171.623 1.00 88.84  ? 56  SER I OG  1 
ATOM 6117 N N   . SER D 2 51  ? 176.660 194.816 175.261 1.00 78.42  ? 57  SER I N   1 
ATOM 6118 C CA  . SER D 2 51  ? 176.316 195.768 176.301 1.00 78.42  ? 57  SER I CA  1 
ATOM 6119 C C   . SER D 2 51  ? 177.507 196.567 176.793 1.00 78.42  ? 57  SER I C   1 
ATOM 6120 O O   . SER D 2 51  ? 177.312 197.625 177.391 1.00 78.42  ? 57  SER I O   1 
ATOM 6121 C CB  . SER D 2 51  ? 175.653 195.039 177.462 1.00 78.42  ? 57  SER I CB  1 
ATOM 6122 O OG  . SER D 2 51  ? 175.351 195.935 178.503 1.00 78.42  ? 57  SER I OG  1 
ATOM 6123 N N   . TYR D 2 52  ? 178.727 196.096 176.566 1.00 70.30  ? 58  TYR I N   1 
ATOM 6124 C CA  . TYR D 2 52  ? 179.872 196.934 176.880 1.00 70.30  ? 58  TYR I CA  1 
ATOM 6125 C C   . TYR D 2 52  ? 179.917 198.152 175.964 1.00 70.30  ? 58  TYR I C   1 
ATOM 6126 O O   . TYR D 2 52  ? 180.400 199.217 176.365 1.00 70.30  ? 58  TYR I O   1 
ATOM 6127 C CB  . TYR D 2 52  ? 181.160 196.128 176.776 1.00 70.30  ? 58  TYR I CB  1 
ATOM 6128 C CG  . TYR D 2 52  ? 182.388 196.989 176.673 1.00 70.30  ? 58  TYR I CG  1 
ATOM 6129 C CD1 . TYR D 2 52  ? 182.904 197.625 177.785 1.00 70.30  ? 58  TYR I CD1 1 
ATOM 6130 C CD2 . TYR D 2 52  ? 183.024 197.174 175.462 1.00 70.30  ? 58  TYR I CD2 1 
ATOM 6131 C CE1 . TYR D 2 52  ? 184.022 198.415 177.696 1.00 70.30  ? 58  TYR I CE1 1 
ATOM 6132 C CE2 . TYR D 2 52  ? 184.139 197.962 175.363 1.00 70.30  ? 58  TYR I CE2 1 
ATOM 6133 C CZ  . TYR D 2 52  ? 184.637 198.579 176.482 1.00 70.30  ? 58  TYR I CZ  1 
ATOM 6134 N N   . PHE D 2 53  ? 179.414 198.017 174.730 1.00 82.40  ? 59  PHE I N   1 
ATOM 6135 C CA  . PHE D 2 53  ? 179.526 199.089 173.742 1.00 82.40  ? 59  PHE I CA  1 
ATOM 6136 C C   . PHE D 2 53  ? 178.470 200.171 173.918 1.00 82.40  ? 59  PHE I C   1 
ATOM 6137 O O   . PHE D 2 53  ? 178.767 201.358 173.730 1.00 82.40  ? 59  PHE I O   1 
ATOM 6138 C CB  . PHE D 2 53  ? 179.458 198.514 172.331 1.00 82.40  ? 59  PHE I CB  1 
ATOM 6139 C CG  . PHE D 2 53  ? 180.679 197.751 171.948 1.00 82.40  ? 59  PHE I CG  1 
ATOM 6140 C CD1 . PHE D 2 53  ? 181.920 198.171 172.375 1.00 82.40  ? 59  PHE I CD1 1 
ATOM 6141 C CD2 . PHE D 2 53  ? 180.597 196.617 171.170 1.00 82.40  ? 59  PHE I CD2 1 
ATOM 6142 C CE1 . PHE D 2 53  ? 183.050 197.479 172.038 1.00 82.40  ? 59  PHE I CE1 1 
ATOM 6143 C CE2 . PHE D 2 53  ? 181.732 195.920 170.831 1.00 82.40  ? 59  PHE I CE2 1 
ATOM 6144 C CZ  . PHE D 2 53  ? 182.961 196.354 171.266 1.00 82.40  ? 59  PHE I CZ  1 
ATOM 6145 N N   . HIS D 2 54  ? 177.232 199.793 174.240 1.00 68.77  ? 60  HIS I N   1 
ATOM 6146 C CA  . HIS D 2 54  ? 176.219 200.812 174.485 1.00 68.77  ? 60  HIS I CA  1 
ATOM 6147 C C   . HIS D 2 54  ? 176.652 201.757 175.590 1.00 68.77  ? 60  HIS I C   1 
ATOM 6148 O O   . HIS D 2 54  ? 176.358 202.959 175.531 1.00 68.77  ? 60  HIS I O   1 
ATOM 6149 C CB  . HIS D 2 54  ? 174.882 200.176 174.836 1.00 68.77  ? 60  HIS I CB  1 
ATOM 6150 C CG  . HIS D 2 54  ? 173.729 201.109 174.681 1.00 68.77  ? 60  HIS I CG  1 
ATOM 6151 N ND1 . HIS D 2 54  ? 172.699 200.884 173.795 1.00 68.77  ? 60  HIS I ND1 1 
ATOM 6152 C CD2 . HIS D 2 54  ? 173.450 202.280 175.295 1.00 68.77  ? 60  HIS I CD2 1 
ATOM 6153 C CE1 . HIS D 2 54  ? 171.833 201.878 173.874 1.00 68.77  ? 60  HIS I CE1 1 
ATOM 6154 N NE2 . HIS D 2 54  ? 172.269 202.741 174.773 1.00 68.77  ? 60  HIS I NE2 1 
ATOM 6155 N N   . SER D 2 55  ? 177.382 201.235 176.575 1.00 69.72  ? 61  SER I N   1 
ATOM 6156 C CA  . SER D 2 55  ? 177.901 202.079 177.638 1.00 69.72  ? 61  SER I CA  1 
ATOM 6157 C C   . SER D 2 55  ? 178.738 203.211 177.075 1.00 69.72  ? 61  SER I C   1 
ATOM 6158 O O   . SER D 2 55  ? 178.498 204.381 177.388 1.00 69.72  ? 61  SER I O   1 
ATOM 6159 C CB  . SER D 2 55  ? 178.739 201.246 178.601 1.00 69.72  ? 61  SER I CB  1 
ATOM 6160 O OG  . SER D 2 55  ? 180.081 201.174 178.150 1.00 69.72  ? 61  SER I OG  1 
ATOM 6161 N N   . ARG D 2 56  ? 179.704 202.896 176.221 1.00 76.66  ? 62  ARG I N   1 
ATOM 6162 C CA  . ARG D 2 56  ? 180.573 203.952 175.727 1.00 76.66  ? 62  ARG I CA  1 
ATOM 6163 C C   . ARG D 2 56  ? 179.947 204.752 174.598 1.00 76.66  ? 62  ARG I C   1 
ATOM 6164 O O   . ARG D 2 56  ? 180.474 205.811 174.249 1.00 76.66  ? 62  ARG I O   1 
ATOM 6165 C CB  . ARG D 2 56  ? 181.911 203.371 175.277 1.00 76.66  ? 62  ARG I CB  1 
ATOM 6166 C CG  . ARG D 2 56  ? 182.091 201.913 175.632 1.00 76.66  ? 62  ARG I CG  1 
ATOM 6167 C CD  . ARG D 2 56  ? 183.302 201.709 176.519 1.00 76.66  ? 62  ARG I CD  1 
ATOM 6168 N NE  . ARG D 2 56  ? 184.403 202.601 176.184 1.00 76.66  ? 62  ARG I NE  1 
ATOM 6169 C CZ  . ARG D 2 56  ? 185.657 202.419 176.576 1.00 76.66  ? 62  ARG I CZ  1 
ATOM 6170 N N   . ILE D 2 57  ? 178.841 204.288 174.026 1.00 70.26  ? 63  ILE I N   1 
ATOM 6171 C CA  . ILE D 2 57  ? 178.252 204.988 172.890 1.00 70.26  ? 63  ILE I CA  1 
ATOM 6172 C C   . ILE D 2 57  ? 177.208 206.004 173.325 1.00 70.26  ? 63  ILE I C   1 
ATOM 6173 O O   . ILE D 2 57  ? 177.314 207.185 172.988 1.00 70.26  ? 63  ILE I O   1 
ATOM 6174 C CB  . ILE D 2 57  ? 177.656 203.978 171.896 1.00 70.26  ? 63  ILE I CB  1 
ATOM 6175 C CG1 . ILE D 2 57  ? 178.783 203.254 171.173 1.00 70.26  ? 63  ILE I CG1 1 
ATOM 6176 C CG2 . ILE D 2 57  ? 176.764 204.694 170.907 1.00 70.26  ? 63  ILE I CG2 1 
ATOM 6177 C CD1 . ILE D 2 57  ? 179.738 204.179 170.489 1.00 70.26  ? 63  ILE I CD1 1 
ATOM 6178 N N   . VAL D 2 58  ? 176.188 205.580 174.080 1.00 69.98  ? 64  VAL I N   1 
ATOM 6179 C CA  . VAL D 2 58  ? 175.003 206.427 174.243 1.00 69.98  ? 64  VAL I CA  1 
ATOM 6180 C C   . VAL D 2 58  ? 175.329 207.747 174.924 1.00 69.98  ? 64  VAL I C   1 
ATOM 6181 O O   . VAL D 2 58  ? 174.566 208.710 174.802 1.00 69.98  ? 64  VAL I O   1 
ATOM 6182 C CB  . VAL D 2 58  ? 173.894 205.679 175.012 1.00 69.98  ? 64  VAL I CB  1 
ATOM 6183 C CG1 . VAL D 2 58  ? 174.221 205.613 176.483 1.00 69.98  ? 64  VAL I CG1 1 
ATOM 6184 C CG2 . VAL D 2 58  ? 172.541 206.338 174.787 1.00 69.98  ? 64  VAL I CG2 1 
ATOM 6185 N N   . GLY D 2 59  ? 176.456 207.832 175.613 1.00 75.97  ? 65  GLY I N   1 
ATOM 6186 C CA  . GLY D 2 59  ? 176.810 209.050 176.299 1.00 75.97  ? 65  GLY I CA  1 
ATOM 6187 C C   . GLY D 2 59  ? 177.370 210.153 175.434 1.00 75.97  ? 65  GLY I C   1 
ATOM 6188 O O   . GLY D 2 59  ? 177.744 211.207 175.953 1.00 75.97  ? 65  GLY I O   1 
ATOM 6189 N N   . GLN D 2 60  ? 177.451 209.954 174.125 1.00 72.44  ? 66  GLN I N   1 
ATOM 6190 C CA  . GLN D 2 60  ? 177.996 210.974 173.248 1.00 72.44  ? 66  GLN I CA  1 
ATOM 6191 C C   . GLN D 2 60  ? 177.102 211.128 172.029 1.00 72.44  ? 66  GLN I C   1 
ATOM 6192 O O   . GLN D 2 60  ? 176.338 210.230 171.672 1.00 72.44  ? 66  GLN I O   1 
ATOM 6193 C CB  . GLN D 2 60  ? 179.429 210.642 172.819 1.00 72.44  ? 66  GLN I CB  1 
ATOM 6194 C CG  . GLN D 2 60  ? 180.493 211.167 173.760 1.00 72.44  ? 66  GLN I CG  1 
ATOM 6195 C CD  . GLN D 2 60  ? 180.575 210.375 175.045 1.00 72.44  ? 66  GLN I CD  1 
ATOM 6196 O OE1 . GLN D 2 60  ? 180.316 209.175 175.066 1.00 72.44  ? 66  GLN I OE1 1 
ATOM 6197 N NE2 . GLN D 2 60  ? 180.937 211.046 176.128 1.00 72.44  ? 66  GLN I NE2 1 
ATOM 6198 N N   . ALA D 2 61  ? 177.193 212.302 171.406 1.00 85.52  ? 67  ALA I N   1 
ATOM 6199 C CA  . ALA D 2 61  ? 176.537 212.573 170.135 1.00 85.52  ? 67  ALA I CA  1 
ATOM 6200 C C   . ALA D 2 61  ? 177.536 213.086 169.106 1.00 85.52  ? 67  ALA I C   1 
ATOM 6201 O O   . ALA D 2 61  ? 177.162 213.836 168.199 1.00 85.52  ? 67  ALA I O   1 
ATOM 6202 C CB  . ALA D 2 61  ? 175.390 213.571 170.311 1.00 85.52  ? 67  ALA I CB  1 
ATOM 6203 N N   . ASP D 2 62  ? 178.798 212.685 169.230 1.00 100.29 ? 68  ASP I N   1 
ATOM 6204 C CA  . ASP D 2 62  ? 179.870 213.187 168.389 1.00 100.29 ? 68  ASP I CA  1 
ATOM 6205 C C   . ASP D 2 62  ? 179.694 212.704 166.948 1.00 100.29 ? 68  ASP I C   1 
ATOM 6206 O O   . ASP D 2 62  ? 178.720 212.035 166.595 1.00 100.29 ? 68  ASP I O   1 
ATOM 6207 C CB  . ASP D 2 62  ? 181.225 212.732 168.935 1.00 100.29 ? 68  ASP I CB  1 
ATOM 6208 C CG  . ASP D 2 62  ? 181.560 213.360 170.274 1.00 100.29 ? 68  ASP I CG  1 
ATOM 6209 O OD1 . ASP D 2 62  ? 181.102 214.491 170.537 1.00 100.29 ? 68  ASP I OD1 1 
ATOM 6210 O OD2 . ASP D 2 62  ? 182.279 212.719 171.068 1.00 100.29 ? 68  ASP I OD2 1 
ATOM 6211 N N   . GLY D 2 63  ? 180.648 213.081 166.103 1.00 106.68 ? 69  GLY I N   1 
ATOM 6212 C CA  . GLY D 2 63  ? 180.669 212.603 164.735 1.00 106.68 ? 69  GLY I CA  1 
ATOM 6213 C C   . GLY D 2 63  ? 181.356 211.264 164.560 1.00 106.68 ? 69  GLY I C   1 
ATOM 6214 O O   . GLY D 2 63  ? 180.711 210.263 164.238 1.00 106.68 ? 69  GLY I O   1 
ATOM 6215 N N   . GLU D 2 64  ? 182.667 211.236 164.779 1.00 108.68 ? 70  GLU I N   1 
ATOM 6216 C CA  . GLU D 2 64  ? 183.474 210.036 164.607 1.00 108.68 ? 70  GLU I CA  1 
ATOM 6217 C C   . GLU D 2 64  ? 183.914 209.526 165.972 1.00 108.68 ? 70  GLU I C   1 
ATOM 6218 O O   . GLU D 2 64  ? 184.484 210.278 166.769 1.00 108.68 ? 70  GLU I O   1 
ATOM 6219 C CB  . GLU D 2 64  ? 184.689 210.317 163.721 1.00 108.68 ? 70  GLU I CB  1 
ATOM 6220 C CG  . GLU D 2 64  ? 185.730 209.215 163.722 1.00 108.68 ? 70  GLU I CG  1 
ATOM 6221 C CD  . GLU D 2 64  ? 186.898 209.519 162.804 1.00 108.68 ? 70  GLU I CD  1 
ATOM 6222 O OE1 . GLU D 2 64  ? 186.811 210.505 162.040 1.00 108.68 ? 70  GLU I OE1 1 
ATOM 6223 O OE2 . GLU D 2 64  ? 187.906 208.782 162.854 1.00 108.68 ? 70  GLU I OE2 1 
ATOM 6224 N N   . LEU D 2 65  ? 183.658 208.248 166.226 1.00 89.98  ? 71  LEU I N   1 
ATOM 6225 C CA  . LEU D 2 65  ? 183.866 207.615 167.517 1.00 89.98  ? 71  LEU I CA  1 
ATOM 6226 C C   . LEU D 2 65  ? 185.065 206.679 167.451 1.00 89.98  ? 71  LEU I C   1 
ATOM 6227 O O   . LEU D 2 65  ? 185.426 206.169 166.389 1.00 89.98  ? 71  LEU I O   1 
ATOM 6228 C CB  . LEU D 2 65  ? 182.607 206.849 167.932 1.00 89.98  ? 71  LEU I CB  1 
ATOM 6229 C CG  . LEU D 2 65  ? 181.411 207.774 168.120 1.00 89.98  ? 71  LEU I CG  1 
ATOM 6230 C CD1 . LEU D 2 65  ? 180.138 207.000 168.297 1.00 89.98  ? 71  LEU I CD1 1 
ATOM 6231 C CD2 . LEU D 2 65  ? 181.664 208.624 169.334 1.00 89.98  ? 71  LEU I CD2 1 
ATOM 6232 N N   . ASN D 2 66  ? 185.688 206.458 168.604 1.00 87.95  ? 72  ASN I N   1 
ATOM 6233 C CA  . ASN D 2 66  ? 186.918 205.669 168.666 1.00 87.95  ? 72  ASN I CA  1 
ATOM 6234 C C   . ASN D 2 66  ? 186.893 204.838 169.944 1.00 87.95  ? 72  ASN I C   1 
ATOM 6235 O O   . ASN D 2 66  ? 187.358 205.295 170.990 1.00 87.95  ? 72  ASN I O   1 
ATOM 6236 C CB  . ASN D 2 66  ? 188.129 206.585 168.626 1.00 87.95  ? 72  ASN I CB  1 
ATOM 6237 C CG  . ASN D 2 66  ? 188.050 207.589 167.501 1.00 87.95  ? 72  ASN I CG  1 
ATOM 6238 O OD1 . ASN D 2 66  ? 187.951 207.219 166.336 1.00 87.95  ? 72  ASN I OD1 1 
ATOM 6239 N ND2 . ASN D 2 66  ? 188.060 208.869 167.847 1.00 87.95  ? 72  ASN I ND2 1 
ATOM 6240 N N   . ILE D 2 67  ? 186.387 203.612 169.855 1.00 110.68 ? 73  ILE I N   1 
ATOM 6241 C CA  . ILE D 2 67  ? 186.219 202.743 171.013 1.00 110.68 ? 73  ILE I CA  1 
ATOM 6242 C C   . ILE D 2 67  ? 187.297 201.677 170.992 1.00 110.68 ? 73  ILE I C   1 
ATOM 6243 O O   . ILE D 2 67  ? 187.465 200.973 169.989 1.00 110.68 ? 73  ILE I O   1 
ATOM 6244 C CB  . ILE D 2 67  ? 184.824 202.102 171.049 1.00 110.68 ? 73  ILE I CB  1 
ATOM 6245 C CG1 . ILE D 2 67  ? 183.767 203.175 171.254 1.00 110.68 ? 73  ILE I CG1 1 
ATOM 6246 C CG2 . ILE D 2 67  ? 184.762 201.078 172.148 1.00 110.68 ? 73  ILE I CG2 1 
ATOM 6247 C CD1 . ILE D 2 67  ? 183.191 203.708 169.991 1.00 110.68 ? 73  ILE I CD1 1 
ATOM 6248 N N   . THR D 2 68  ? 188.018 201.551 172.100 1.00 135.98 ? 74  THR I N   1 
ATOM 6249 C CA  . THR D 2 68  ? 189.080 200.571 172.232 1.00 135.98 ? 74  THR I CA  1 
ATOM 6250 C C   . THR D 2 68  ? 188.619 199.475 173.184 1.00 135.98 ? 74  THR I C   1 
ATOM 6251 O O   . THR D 2 68  ? 187.788 199.706 174.065 1.00 135.98 ? 74  THR I O   1 
ATOM 6252 C CB  . THR D 2 68  ? 190.372 201.234 172.732 1.00 135.98 ? 74  THR I CB  1 
ATOM 6253 O OG1 . THR D 2 68  ? 190.774 202.243 171.797 1.00 135.98 ? 74  THR I OG1 1 
ATOM 6254 C CG2 . THR D 2 68  ? 191.505 200.226 172.830 1.00 135.98 ? 74  THR I CG2 1 
ATOM 6255 N N   . LEU D 2 69  ? 189.161 198.279 173.002 1.00 135.42 ? 75  LEU I N   1 
ATOM 6256 C CA  . LEU D 2 69  ? 188.719 197.118 173.748 1.00 135.42 ? 75  LEU I CA  1 
ATOM 6257 C C   . LEU D 2 69  ? 189.852 196.590 174.617 1.00 135.42 ? 75  LEU I C   1 
ATOM 6258 O O   . LEU D 2 69  ? 191.026 196.744 174.267 1.00 135.42 ? 75  LEU I O   1 
ATOM 6259 C CB  . LEU D 2 69  ? 188.253 196.016 172.790 1.00 135.42 ? 75  LEU I CB  1 
ATOM 6260 C CG  . LEU D 2 69  ? 186.776 195.980 172.405 1.00 135.42 ? 75  LEU I CG  1 
ATOM 6261 C CD1 . LEU D 2 69  ? 185.911 195.620 173.592 1.00 135.42 ? 75  LEU I CD1 1 
ATOM 6262 C CD2 . LEU D 2 69  ? 186.361 197.321 171.830 1.00 135.42 ? 75  LEU I CD2 1 
ATOM 6263 N N   . PRO D 2 70  ? 189.547 195.971 175.752 1.00 162.19 ? 76  PRO I N   1 
ATOM 6264 C CA  . PRO D 2 70  ? 190.615 195.460 176.611 1.00 162.19 ? 76  PRO I CA  1 
ATOM 6265 C C   . PRO D 2 70  ? 191.336 194.293 175.957 1.00 162.19 ? 76  PRO I C   1 
ATOM 6266 O O   . PRO D 2 70  ? 190.841 193.648 175.030 1.00 162.19 ? 76  PRO I O   1 
ATOM 6267 C CB  . PRO D 2 70  ? 189.878 195.017 177.878 1.00 162.19 ? 76  PRO I CB  1 
ATOM 6268 C CG  . PRO D 2 70  ? 188.478 194.787 177.437 1.00 162.19 ? 76  PRO I CG  1 
ATOM 6269 C CD  . PRO D 2 70  ? 188.219 195.796 176.363 1.00 162.19 ? 76  PRO I CD  1 
ATOM 6270 N N   . GLU D 2 71  ? 192.539 194.028 176.469 1.00 187.21 ? 77  GLU I N   1 
ATOM 6271 C CA  . GLU D 2 71  ? 193.301 192.868 176.018 1.00 187.21 ? 77  GLU I CA  1 
ATOM 6272 C C   . GLU D 2 71  ? 192.538 191.574 176.264 1.00 187.21 ? 77  GLU I C   1 
ATOM 6273 O O   . GLU D 2 71  ? 192.793 190.564 175.597 1.00 187.21 ? 77  GLU I O   1 
ATOM 6274 C CB  . GLU D 2 71  ? 194.658 192.835 176.728 1.00 187.21 ? 77  GLU I CB  1 
ATOM 6275 C CG  . GLU D 2 71  ? 195.545 191.651 176.377 1.00 187.21 ? 77  GLU I CG  1 
ATOM 6276 C CD  . GLU D 2 71  ? 195.970 191.640 174.924 1.00 187.21 ? 77  GLU I CD  1 
ATOM 6277 O OE1 . GLU D 2 71  ? 196.413 192.695 174.426 1.00 187.21 ? 77  GLU I OE1 1 
ATOM 6278 O OE2 . GLU D 2 71  ? 195.865 190.574 174.282 1.00 187.21 ? 77  GLU I OE2 1 
ATOM 6279 N N   . GLU D 2 72  ? 191.588 191.596 177.201 1.00 203.02 ? 78  GLU I N   1 
ATOM 6280 C CA  . GLU D 2 72  ? 190.817 190.399 177.518 1.00 203.02 ? 78  GLU I CA  1 
ATOM 6281 C C   . GLU D 2 72  ? 190.055 189.889 176.301 1.00 203.02 ? 78  GLU I C   1 
ATOM 6282 O O   . GLU D 2 72  ? 189.923 188.675 176.105 1.00 203.02 ? 78  GLU I O   1 
ATOM 6283 C CB  . GLU D 2 72  ? 189.857 190.697 178.670 1.00 203.02 ? 78  GLU I CB  1 
ATOM 6284 C CG  . GLU D 2 72  ? 189.082 189.500 179.157 1.00 203.02 ? 78  GLU I CG  1 
ATOM 6285 C CD  . GLU D 2 72  ? 187.717 189.400 178.521 1.00 203.02 ? 78  GLU I CD  1 
ATOM 6286 O OE1 . GLU D 2 72  ? 187.173 190.449 178.115 1.00 203.02 ? 78  GLU I OE1 1 
ATOM 6287 O OE2 . GLU D 2 72  ? 187.189 188.272 178.428 1.00 203.02 ? 78  GLU I OE2 1 
ATOM 6288 N N   . VAL D 2 73  ? 189.544 190.796 175.476 1.00 193.34 ? 79  VAL I N   1 
ATOM 6289 C CA  . VAL D 2 73  ? 188.886 190.413 174.234 1.00 193.34 ? 79  VAL I CA  1 
ATOM 6290 C C   . VAL D 2 73  ? 189.944 190.228 173.155 1.00 193.34 ? 79  VAL I C   1 
ATOM 6291 O O   . VAL D 2 73  ? 190.754 191.129 172.903 1.00 193.34 ? 79  VAL I O   1 
ATOM 6292 C CB  . VAL D 2 73  ? 187.850 191.469 173.819 1.00 193.34 ? 79  VAL I CB  1 
ATOM 6293 C CG1 . VAL D 2 73  ? 187.164 191.054 172.526 1.00 193.34 ? 79  VAL I CG1 1 
ATOM 6294 C CG2 . VAL D 2 73  ? 186.835 191.687 174.928 1.00 193.34 ? 79  VAL I CG2 1 
ATOM 6295 N N   . THR D 2 74  ? 189.937 189.067 172.510 1.00 186.95 ? 80  THR I N   1 
ATOM 6296 C CA  . THR D 2 74  ? 190.942 188.722 171.516 1.00 186.95 ? 80  THR I CA  1 
ATOM 6297 C C   . THR D 2 74  ? 190.415 188.968 170.112 1.00 186.95 ? 80  THR I C   1 
ATOM 6298 O O   . THR D 2 74  ? 189.224 188.801 169.845 1.00 186.95 ? 80  THR I O   1 
ATOM 6299 C CB  . THR D 2 74  ? 191.366 187.262 171.647 1.00 186.95 ? 80  THR I CB  1 
ATOM 6300 O OG1 . THR D 2 74  ? 192.288 186.942 170.600 1.00 186.95 ? 80  THR I OG1 1 
ATOM 6301 C CG2 . THR D 2 74  ? 190.164 186.352 171.545 1.00 186.95 ? 80  THR I CG2 1 
ATOM 6302 N N   . VAL D 2 75  ? 191.319 189.358 169.215 1.00 170.47 ? 81  VAL I N   1 
ATOM 6303 C CA  . VAL D 2 75  ? 190.923 189.622 167.835 1.00 170.47 ? 81  VAL I CA  1 
ATOM 6304 C C   . VAL D 2 75  ? 190.361 188.361 167.182 1.00 170.47 ? 81  VAL I C   1 
ATOM 6305 O O   . VAL D 2 75  ? 189.270 188.377 166.597 1.00 170.47 ? 81  VAL I O   1 
ATOM 6306 C CB  . VAL D 2 75  ? 192.115 190.203 167.042 1.00 170.47 ? 81  VAL I CB  1 
ATOM 6307 C CG1 . VAL D 2 75  ? 192.434 191.605 167.521 1.00 170.47 ? 81  VAL I CG1 1 
ATOM 6308 C CG2 . VAL D 2 75  ? 193.347 189.317 167.161 1.00 170.47 ? 81  VAL I CG2 1 
ATOM 6309 N N   . LYS D 2 76  ? 191.060 187.236 167.335 1.00 161.35 ? 82  LYS I N   1 
ATOM 6310 C CA  . LYS D 2 76  ? 190.737 186.022 166.591 1.00 161.35 ? 82  LYS I CA  1 
ATOM 6311 C C   . LYS D 2 76  ? 189.288 185.612 166.799 1.00 161.35 ? 82  LYS I C   1 
ATOM 6312 O O   . LYS D 2 76  ? 188.583 185.300 165.835 1.00 161.35 ? 82  LYS I O   1 
ATOM 6313 C CB  . LYS D 2 76  ? 191.708 184.886 166.979 1.00 161.35 ? 82  LYS I CB  1 
ATOM 6314 C CG  . LYS D 2 76  ? 191.724 184.475 168.450 1.00 161.35 ? 82  LYS I CG  1 
ATOM 6315 C CD  . LYS D 2 76  ? 190.783 183.326 168.774 1.00 161.35 ? 82  LYS I CD  1 
ATOM 6316 C CE  . LYS D 2 76  ? 190.922 182.904 170.232 1.00 161.35 ? 82  LYS I CE  1 
ATOM 6317 N NZ  . LYS D 2 76  ? 189.988 181.797 170.592 1.00 161.35 ? 82  LYS I NZ  1 
ATOM 6318 N N   . GLY D 2 77  ? 188.805 185.657 168.039 1.00 153.57 ? 83  GLY I N   1 
ATOM 6319 C CA  . GLY D 2 77  ? 187.384 185.482 168.235 1.00 153.57 ? 83  GLY I CA  1 
ATOM 6320 C C   . GLY D 2 77  ? 186.585 186.713 167.905 1.00 153.57 ? 83  GLY I C   1 
ATOM 6321 O O   . GLY D 2 77  ? 185.368 186.619 167.729 1.00 153.57 ? 83  GLY I O   1 
ATOM 6322 N N   . PHE D 2 78  ? 187.242 187.867 167.800 1.00 141.36 ? 84  PHE I N   1 
ATOM 6323 C CA  . PHE D 2 78  ? 186.481 189.099 167.665 1.00 141.36 ? 84  PHE I CA  1 
ATOM 6324 C C   . PHE D 2 78  ? 185.877 189.239 166.275 1.00 141.36 ? 84  PHE I C   1 
ATOM 6325 O O   . PHE D 2 78  ? 184.730 189.681 166.146 1.00 141.36 ? 84  PHE I O   1 
ATOM 6326 C CB  . PHE D 2 78  ? 187.339 190.314 168.006 1.00 141.36 ? 84  PHE I CB  1 
ATOM 6327 C CG  . PHE D 2 78  ? 186.651 191.608 167.744 1.00 141.36 ? 84  PHE I CG  1 
ATOM 6328 C CD1 . PHE D 2 78  ? 185.545 191.966 168.492 1.00 141.36 ? 84  PHE I CD1 1 
ATOM 6329 C CD2 . PHE D 2 78  ? 187.109 192.473 166.774 1.00 141.36 ? 84  PHE I CD2 1 
ATOM 6330 C CE1 . PHE D 2 78  ? 184.899 193.154 168.261 1.00 141.36 ? 84  PHE I CE1 1 
ATOM 6331 C CE2 . PHE D 2 78  ? 186.470 193.661 166.543 1.00 141.36 ? 84  PHE I CE2 1 
ATOM 6332 C CZ  . PHE D 2 78  ? 185.365 194.004 167.285 1.00 141.36 ? 84  PHE I CZ  1 
ATOM 6333 N N   . GLU D 2 79  ? 186.611 188.872 165.217 1.00 127.98 ? 85  GLU I N   1 
ATOM 6334 C CA  . GLU D 2 79  ? 186.018 189.051 163.889 1.00 127.98 ? 85  GLU I CA  1 
ATOM 6335 C C   . GLU D 2 79  ? 184.688 188.322 163.737 1.00 127.98 ? 85  GLU I C   1 
ATOM 6336 O O   . GLU D 2 79  ? 183.731 188.935 163.236 1.00 127.98 ? 85  GLU I O   1 
ATOM 6337 C CB  . GLU D 2 79  ? 186.959 188.644 162.746 1.00 127.98 ? 85  GLU I CB  1 
ATOM 6338 C CG  . GLU D 2 79  ? 188.190 189.487 162.549 1.00 127.98 ? 85  GLU I CG  1 
ATOM 6339 C CD  . GLU D 2 79  ? 189.304 189.076 163.447 1.00 127.98 ? 85  GLU I CD  1 
ATOM 6340 O OE1 . GLU D 2 79  ? 189.120 188.084 164.160 1.00 127.98 ? 85  GLU I OE1 1 
ATOM 6341 O OE2 . GLU D 2 79  ? 190.360 189.727 163.435 1.00 127.98 ? 85  GLU I OE2 1 
ATOM 6342 N N   . PRO D 2 80  ? 184.542 187.054 164.131 1.00 114.32 ? 86  PRO I N   1 
ATOM 6343 C CA  . PRO D 2 80  ? 183.225 186.413 163.991 1.00 114.32 ? 86  PRO I CA  1 
ATOM 6344 C C   . PRO D 2 80  ? 182.168 186.970 164.922 1.00 114.32 ? 86  PRO I C   1 
ATOM 6345 O O   . PRO D 2 80  ? 180.979 186.738 164.677 1.00 114.32 ? 86  PRO I O   1 
ATOM 6346 C CB  . PRO D 2 80  ? 183.516 184.939 164.292 1.00 114.32 ? 86  PRO I CB  1 
ATOM 6347 C CG  . PRO D 2 80  ? 184.735 184.958 165.110 1.00 114.32 ? 86  PRO I CG  1 
ATOM 6348 C CD  . PRO D 2 80  ? 185.558 186.090 164.592 1.00 114.32 ? 86  PRO I CD  1 
ATOM 6349 N N   . LEU D 2 81  ? 182.548 187.677 165.985 1.00 116.34 ? 87  LEU I N   1 
ATOM 6350 C CA  . LEU D 2 81  ? 181.544 188.277 166.855 1.00 116.34 ? 87  LEU I CA  1 
ATOM 6351 C C   . LEU D 2 81  ? 180.687 189.267 166.085 1.00 116.34 ? 87  LEU I C   1 
ATOM 6352 O O   . LEU D 2 81  ? 179.453 189.219 166.147 1.00 116.34 ? 87  LEU I O   1 
ATOM 6353 C CB  . LEU D 2 81  ? 182.218 188.963 168.038 1.00 116.34 ? 87  LEU I CB  1 
ATOM 6354 C CG  . LEU D 2 81  ? 182.947 188.061 169.025 1.00 116.34 ? 87  LEU I CG  1 
ATOM 6355 C CD1 . LEU D 2 81  ? 183.684 188.883 170.065 1.00 116.34 ? 87  LEU I CD1 1 
ATOM 6356 C CD2 . LEU D 2 81  ? 181.947 187.136 169.688 1.00 116.34 ? 87  LEU I CD2 1 
ATOM 6357 N N   . ILE D 2 82  ? 181.326 190.163 165.332 1.00 104.69 ? 88  ILE I N   1 
ATOM 6358 C CA  . ILE D 2 82  ? 180.575 191.146 164.561 1.00 104.69 ? 88  ILE I CA  1 
ATOM 6359 C C   . ILE D 2 82  ? 179.780 190.458 163.466 1.00 104.69 ? 88  ILE I C   1 
ATOM 6360 O O   . ILE D 2 82  ? 178.659 190.864 163.141 1.00 104.69 ? 88  ILE I O   1 
ATOM 6361 C CB  . ILE D 2 82  ? 181.519 192.211 163.986 1.00 104.69 ? 88  ILE I CB  1 
ATOM 6362 C CG1 . ILE D 2 82  ? 182.591 192.588 165.010 1.00 104.69 ? 88  ILE I CG1 1 
ATOM 6363 C CG2 . ILE D 2 82  ? 180.728 193.430 163.583 1.00 104.69 ? 88  ILE I CG2 1 
ATOM 6364 C CD1 . ILE D 2 82  ? 182.042 193.185 166.275 1.00 104.69 ? 88  ILE I CD1 1 
ATOM 6365 N N   . GLN D 2 83  ? 180.348 189.406 162.877 1.00 106.70 ? 89  GLN I N   1 
ATOM 6366 C CA  . GLN D 2 83  ? 179.631 188.667 161.849 1.00 106.70 ? 89  GLN I CA  1 
ATOM 6367 C C   . GLN D 2 83  ? 178.362 188.040 162.403 1.00 106.70 ? 89  GLN I C   1 
ATOM 6368 O O   . GLN D 2 83  ? 177.321 188.048 161.741 1.00 106.70 ? 89  GLN I O   1 
ATOM 6369 C CB  . GLN D 2 83  ? 180.537 187.598 161.243 1.00 106.70 ? 89  GLN I CB  1 
ATOM 6370 C CG  . GLN D 2 83  ? 180.006 187.026 159.942 1.00 106.70 ? 89  GLN I CG  1 
ATOM 6371 C CD  . GLN D 2 83  ? 179.398 188.086 159.051 1.00 106.70 ? 89  GLN I CD  1 
ATOM 6372 O OE1 . GLN D 2 83  ? 178.177 188.202 158.952 1.00 106.70 ? 89  GLN I OE1 1 
ATOM 6373 N NE2 . GLN D 2 83  ? 180.248 188.870 158.400 1.00 106.70 ? 89  GLN I NE2 1 
ATOM 6374 N N   . PHE D 2 84  ? 178.428 187.483 163.613 1.00 127.91 ? 90  PHE I N   1 
ATOM 6375 C CA  . PHE D 2 84  ? 177.237 186.889 164.206 1.00 127.91 ? 90  PHE I CA  1 
ATOM 6376 C C   . PHE D 2 84  ? 176.270 187.962 164.684 1.00 127.91 ? 90  PHE I C   1 
ATOM 6377 O O   . PHE D 2 84  ? 175.062 187.718 164.770 1.00 127.91 ? 90  PHE I O   1 
ATOM 6378 C CB  . PHE D 2 84  ? 177.621 185.966 165.360 1.00 127.91 ? 90  PHE I CB  1 
ATOM 6379 C CG  . PHE D 2 84  ? 176.719 184.776 165.502 1.00 127.91 ? 90  PHE I CG  1 
ATOM 6380 C CD1 . PHE D 2 84  ? 176.888 183.669 164.691 1.00 127.91 ? 90  PHE I CD1 1 
ATOM 6381 C CD2 . PHE D 2 84  ? 175.699 184.765 166.432 1.00 127.91 ? 90  PHE I CD2 1 
ATOM 6382 C CE1 . PHE D 2 84  ? 176.064 182.571 164.806 1.00 127.91 ? 90  PHE I CE1 1 
ATOM 6383 C CE2 . PHE D 2 84  ? 174.871 183.664 166.554 1.00 127.91 ? 90  PHE I CE2 1 
ATOM 6384 C CZ  . PHE D 2 84  ? 175.056 182.567 165.737 1.00 127.91 ? 90  PHE I CZ  1 
ATOM 6385 N N   . ALA D 2 85  ? 176.789 189.143 165.018 1.00 106.21 ? 91  ALA I N   1 
ATOM 6386 C CA  . ALA D 2 85  ? 175.921 190.278 165.297 1.00 106.21 ? 91  ALA I CA  1 
ATOM 6387 C C   . ALA D 2 85  ? 175.141 190.678 164.055 1.00 106.21 ? 91  ALA I C   1 
ATOM 6388 O O   . ALA D 2 85  ? 173.960 191.031 164.135 1.00 106.21 ? 91  ALA I O   1 
ATOM 6389 C CB  . ALA D 2 85  ? 176.747 191.456 165.809 1.00 106.21 ? 91  ALA I CB  1 
ATOM 6390 N N   . TYR D 2 86  ? 175.790 190.627 162.896 1.00 98.84  ? 92  TYR I N   1 
ATOM 6391 C CA  . TYR D 2 86  ? 175.156 191.091 161.670 1.00 98.84  ? 92  TYR I CA  1 
ATOM 6392 C C   . TYR D 2 86  ? 174.239 190.030 161.069 1.00 98.84  ? 92  TYR I C   1 
ATOM 6393 O O   . TYR D 2 86  ? 173.026 190.232 160.960 1.00 98.84  ? 92  TYR I O   1 
ATOM 6394 C CB  . TYR D 2 86  ? 176.227 191.519 160.666 1.00 98.84  ? 92  TYR I CB  1 
ATOM 6395 C CG  . TYR D 2 86  ? 176.642 192.964 160.812 1.00 98.84  ? 92  TYR I CG  1 
ATOM 6396 C CD1 . TYR D 2 86  ? 175.762 193.988 160.508 1.00 98.84  ? 92  TYR I CD1 1 
ATOM 6397 C CD2 . TYR D 2 86  ? 177.911 193.304 161.261 1.00 98.84  ? 92  TYR I CD2 1 
ATOM 6398 C CE1 . TYR D 2 86  ? 176.133 195.307 160.640 1.00 98.84  ? 92  TYR I CE1 1 
ATOM 6399 C CE2 . TYR D 2 86  ? 178.289 194.623 161.396 1.00 98.84  ? 92  TYR I CE2 1 
ATOM 6400 C CZ  . TYR D 2 86  ? 177.399 195.619 161.083 1.00 98.84  ? 92  TYR I CZ  1 
ATOM 6401 N N   . THR D 2 87  ? 174.801 188.885 160.684 1.00 115.90 ? 93  THR I N   1 
ATOM 6402 C CA  . THR D 2 87  ? 174.068 187.860 159.952 1.00 115.90 ? 93  THR I CA  1 
ATOM 6403 C C   . THR D 2 87  ? 173.772 186.604 160.758 1.00 115.90 ? 93  THR I C   1 
ATOM 6404 O O   . THR D 2 87  ? 173.202 185.658 160.203 1.00 115.90 ? 93  THR I O   1 
ATOM 6405 C CB  . THR D 2 87  ? 174.839 187.465 158.688 1.00 115.90 ? 93  THR I CB  1 
ATOM 6406 O OG1 . THR D 2 87  ? 176.113 186.924 159.059 1.00 115.90 ? 93  THR I OG1 1 
ATOM 6407 C CG2 . THR D 2 87  ? 175.048 188.674 157.799 1.00 115.90 ? 93  THR I CG2 1 
ATOM 6408 N N   . ALA D 2 88  ? 174.149 186.556 162.035 1.00 136.37 ? 94  ALA I N   1 
ATOM 6409 C CA  . ALA D 2 88  ? 173.832 185.432 162.919 1.00 136.37 ? 94  ALA I CA  1 
ATOM 6410 C C   . ALA D 2 88  ? 174.373 184.105 162.392 1.00 136.37 ? 94  ALA I C   1 
ATOM 6411 O O   . ALA D 2 88  ? 173.772 183.049 162.604 1.00 136.37 ? 94  ALA I O   1 
ATOM 6412 C CB  . ALA D 2 88  ? 172.325 185.331 163.162 1.00 136.37 ? 94  ALA I CB  1 
ATOM 6413 N N   . LYS D 2 89  ? 175.515 184.143 161.713 1.00 137.93 ? 95  LYS I N   1 
ATOM 6414 C CA  . LYS D 2 89  ? 176.180 182.941 161.227 1.00 137.93 ? 95  LYS I CA  1 
ATOM 6415 C C   . LYS D 2 89  ? 177.647 182.996 161.626 1.00 137.93 ? 95  LYS I C   1 
ATOM 6416 O O   . LYS D 2 89  ? 178.293 184.038 161.478 1.00 137.93 ? 95  LYS I O   1 
ATOM 6417 C CB  . LYS D 2 89  ? 176.040 182.806 159.709 1.00 137.93 ? 95  LYS I CB  1 
ATOM 6418 C CG  . LYS D 2 89  ? 174.921 181.877 159.278 1.00 137.93 ? 95  LYS I CG  1 
ATOM 6419 C CD  . LYS D 2 89  ? 173.565 182.542 159.433 1.00 137.93 ? 95  LYS I CD  1 
ATOM 6420 C CE  . LYS D 2 89  ? 172.482 181.762 158.714 1.00 137.93 ? 95  LYS I CE  1 
ATOM 6421 N NZ  . LYS D 2 89  ? 171.288 182.604 158.437 1.00 137.93 ? 95  LYS I NZ  1 
ATOM 6422 N N   . LEU D 2 90  ? 178.170 181.880 162.128 1.00 136.91 ? 96  LEU I N   1 
ATOM 6423 C CA  . LEU D 2 90  ? 179.537 181.821 162.619 1.00 136.91 ? 96  LEU I CA  1 
ATOM 6424 C C   . LEU D 2 90  ? 180.320 180.728 161.915 1.00 136.91 ? 96  LEU I C   1 
ATOM 6425 O O   . LEU D 2 90  ? 179.765 179.710 161.492 1.00 136.91 ? 96  LEU I O   1 
ATOM 6426 C CB  . LEU D 2 90  ? 179.589 181.572 164.132 1.00 136.91 ? 96  LEU I CB  1 
ATOM 6427 C CG  . LEU D 2 90  ? 178.914 180.336 164.736 1.00 136.91 ? 96  LEU I CG  1 
ATOM 6428 C CD1 . LEU D 2 90  ? 179.793 179.101 164.679 1.00 136.91 ? 96  LEU I CD1 1 
ATOM 6429 C CD2 . LEU D 2 90  ? 178.566 180.639 166.178 1.00 136.91 ? 96  LEU I CD2 1 
ATOM 6430 N N   . ILE D 2 91  ? 181.623 180.950 161.811 1.00 163.25 ? 97  ILE I N   1 
ATOM 6431 C CA  . ILE D 2 91  ? 182.573 179.946 161.359 1.00 163.25 ? 97  ILE I CA  1 
ATOM 6432 C C   . ILE D 2 91  ? 183.592 179.771 162.478 1.00 163.25 ? 97  ILE I C   1 
ATOM 6433 O O   . ILE D 2 91  ? 184.107 180.759 163.014 1.00 163.25 ? 97  ILE I O   1 
ATOM 6434 C CB  . ILE D 2 91  ? 183.236 180.352 160.026 1.00 163.25 ? 97  ILE I CB  1 
ATOM 6435 C CG1 . ILE D 2 91  ? 183.994 179.182 159.395 1.00 163.25 ? 97  ILE I CG1 1 
ATOM 6436 C CG2 . ILE D 2 91  ? 184.125 181.588 160.174 1.00 163.25 ? 97  ILE I CG2 1 
ATOM 6437 C CD1 . ILE D 2 91  ? 183.084 178.162 158.749 1.00 163.25 ? 97  ILE I CD1 1 
ATOM 6438 N N   . LEU D 2 92  ? 183.835 178.525 162.876 1.00 165.79 ? 98  LEU I N   1 
ATOM 6439 C CA  . LEU D 2 92  ? 184.781 178.283 163.957 1.00 165.79 ? 98  LEU I CA  1 
ATOM 6440 C C   . LEU D 2 92  ? 185.149 176.810 163.995 1.00 165.79 ? 98  LEU I C   1 
ATOM 6441 O O   . LEU D 2 92  ? 184.315 175.938 163.735 1.00 165.79 ? 98  LEU I O   1 
ATOM 6442 C CB  . LEU D 2 92  ? 184.210 178.714 165.311 1.00 165.79 ? 98  LEU I CB  1 
ATOM 6443 C CG  . LEU D 2 92  ? 185.250 179.074 166.366 1.00 165.79 ? 98  LEU I CG  1 
ATOM 6444 C CD1 . LEU D 2 92  ? 186.134 180.196 165.860 1.00 165.79 ? 98  LEU I CD1 1 
ATOM 6445 C CD2 . LEU D 2 92  ? 184.560 179.469 167.655 1.00 165.79 ? 98  LEU I CD2 1 
ATOM 6446 N N   . SER D 2 93  ? 186.402 176.550 164.338 1.00 198.05 ? 99  SER I N   1 
ATOM 6447 C CA  . SER D 2 93  ? 186.930 175.208 164.502 1.00 198.05 ? 99  SER I CA  1 
ATOM 6448 C C   . SER D 2 93  ? 187.329 175.008 165.958 1.00 198.05 ? 99  SER I C   1 
ATOM 6449 O O   . SER D 2 93  ? 187.118 175.874 166.809 1.00 198.05 ? 99  SER I O   1 
ATOM 6450 C CB  . SER D 2 93  ? 188.110 174.967 163.560 1.00 198.05 ? 99  SER I CB  1 
ATOM 6451 O OG  . SER D 2 93  ? 189.182 175.830 163.875 1.00 198.05 ? 99  SER I OG  1 
ATOM 6452 N N   . LYS D 2 94  ? 187.927 173.853 166.239 1.00 221.77 ? 100 LYS I N   1 
ATOM 6453 C CA  . LYS D 2 94  ? 188.083 173.417 167.619 1.00 221.77 ? 100 LYS I CA  1 
ATOM 6454 C C   . LYS D 2 94  ? 189.260 174.064 168.338 1.00 221.77 ? 100 LYS I C   1 
ATOM 6455 O O   . LYS D 2 94  ? 189.331 173.973 169.568 1.00 221.77 ? 100 LYS I O   1 
ATOM 6456 C CB  . LYS D 2 94  ? 188.223 171.893 167.665 1.00 221.77 ? 100 LYS I CB  1 
ATOM 6457 C CG  . LYS D 2 94  ? 189.645 171.385 167.500 1.00 221.77 ? 100 LYS I CG  1 
ATOM 6458 C CD  . LYS D 2 94  ? 189.732 169.893 167.779 1.00 221.77 ? 100 LYS I CD  1 
ATOM 6459 C CE  . LYS D 2 94  ? 191.157 169.391 167.638 1.00 221.77 ? 100 LYS I CE  1 
ATOM 6460 N NZ  . LYS D 2 94  ? 192.065 170.044 168.619 1.00 221.77 ? 100 LYS I NZ  1 
ATOM 6461 N N   . GLU D 2 95  ? 190.185 174.709 167.622 1.00 220.37 ? 101 GLU I N   1 
ATOM 6462 C CA  . GLU D 2 95  ? 191.358 175.248 168.305 1.00 220.37 ? 101 GLU I CA  1 
ATOM 6463 C C   . GLU D 2 95  ? 191.059 176.550 169.043 1.00 220.37 ? 101 GLU I C   1 
ATOM 6464 O O   . GLU D 2 95  ? 191.678 176.819 170.077 1.00 220.37 ? 101 GLU I O   1 
ATOM 6465 C CB  . GLU D 2 95  ? 192.511 175.459 167.320 1.00 220.37 ? 101 GLU I CB  1 
ATOM 6466 C CG  . GLU D 2 95  ? 192.320 176.594 166.339 1.00 220.37 ? 101 GLU I CG  1 
ATOM 6467 C CD  . GLU D 2 95  ? 191.787 176.121 165.012 1.00 220.37 ? 101 GLU I CD  1 
ATOM 6468 O OE1 . GLU D 2 95  ? 191.298 174.974 164.943 1.00 220.37 ? 101 GLU I OE1 1 
ATOM 6469 O OE2 . GLU D 2 95  ? 191.852 176.892 164.031 1.00 220.37 ? 101 GLU I OE2 1 
ATOM 6470 N N   . ASN D 2 96  ? 190.126 177.361 168.544 1.00 204.01 ? 102 ASN I N   1 
ATOM 6471 C CA  . ASN D 2 96  ? 189.810 178.664 169.132 1.00 204.01 ? 102 ASN I CA  1 
ATOM 6472 C C   . ASN D 2 96  ? 188.365 178.640 169.618 1.00 204.01 ? 102 ASN I C   1 
ATOM 6473 O O   . ASN D 2 96  ? 187.447 179.092 168.932 1.00 204.01 ? 102 ASN I O   1 
ATOM 6474 C CB  . ASN D 2 96  ? 190.053 179.783 168.110 1.00 204.01 ? 102 ASN I CB  1 
ATOM 6475 C CG  . ASN D 2 96  ? 189.422 179.489 166.763 1.00 204.01 ? 102 ASN I CG  1 
ATOM 6476 O OD1 . ASN D 2 96  ? 188.763 178.467 166.582 1.00 204.01 ? 102 ASN I OD1 1 
ATOM 6477 N ND2 . ASN D 2 96  ? 189.621 180.391 165.810 1.00 204.01 ? 102 ASN I ND2 1 
ATOM 6478 N N   . VAL D 2 97  ? 188.165 178.106 170.820 1.00 264.19 ? 103 VAL I N   1 
ATOM 6479 C CA  . VAL D 2 97  ? 186.826 177.955 171.374 1.00 264.19 ? 103 VAL I CA  1 
ATOM 6480 C C   . VAL D 2 97  ? 186.760 178.555 172.771 1.00 264.19 ? 103 VAL I C   1 
ATOM 6481 O O   . VAL D 2 97  ? 185.797 179.249 173.115 1.00 264.19 ? 103 VAL I O   1 
ATOM 6482 C CB  . VAL D 2 97  ? 186.400 176.476 171.386 1.00 264.19 ? 103 VAL I CB  1 
ATOM 6483 C CG1 . VAL D 2 97  ? 185.057 176.321 172.060 1.00 264.19 ? 103 VAL I CG1 1 
ATOM 6484 C CG2 . VAL D 2 97  ? 186.351 175.929 169.971 1.00 264.19 ? 103 VAL I CG2 1 
ATOM 6485 N N   . ASP D 2 98  ? 187.788 178.284 173.584 1.00 304.00 ? 104 ASP I N   1 
ATOM 6486 C CA  . ASP D 2 98  ? 187.714 178.558 175.018 1.00 304.00 ? 104 ASP I CA  1 
ATOM 6487 C C   . ASP D 2 98  ? 187.458 180.034 175.303 1.00 304.00 ? 104 ASP I C   1 
ATOM 6488 O O   . ASP D 2 98  ? 186.619 180.373 176.147 1.00 304.00 ? 104 ASP I O   1 
ATOM 6489 C CB  . ASP D 2 98  ? 189.002 178.107 175.702 1.00 304.00 ? 104 ASP I CB  1 
ATOM 6490 C CG  . ASP D 2 98  ? 190.246 178.660 175.030 1.00 304.00 ? 104 ASP I CG  1 
ATOM 6491 O OD1 . ASP D 2 98  ? 190.124 179.207 173.915 1.00 304.00 ? 104 ASP I OD1 1 
ATOM 6492 O OD2 . ASP D 2 98  ? 191.338 178.551 175.621 1.00 304.00 ? 104 ASP I OD2 1 
ATOM 6493 N N   . GLU D 2 99  ? 188.155 180.924 174.607 1.00 264.00 ? 105 GLU I N   1 
ATOM 6494 C CA  . GLU D 2 99  ? 187.917 182.343 174.867 1.00 264.00 ? 105 GLU I CA  1 
ATOM 6495 C C   . GLU D 2 99  ? 186.622 182.827 174.296 1.00 264.00 ? 105 GLU I C   1 
ATOM 6496 O O   . GLU D 2 99  ? 186.429 184.040 174.228 1.00 264.00 ? 105 GLU I O   1 
ATOM 6497 C CB  . GLU D 2 99  ? 189.079 183.178 174.334 1.00 264.00 ? 105 GLU I CB  1 
ATOM 6498 C CG  . GLU D 2 99  ? 190.385 182.907 175.053 1.00 264.00 ? 105 GLU I CG  1 
ATOM 6499 C CD  . GLU D 2 99  ? 191.563 183.597 174.406 1.00 264.00 ? 105 GLU I CD  1 
ATOM 6500 O OE1 . GLU D 2 99  ? 191.375 184.209 173.339 1.00 264.00 ? 105 GLU I OE1 1 
ATOM 6501 O OE2 . GLU D 2 99  ? 192.674 183.530 174.968 1.00 264.00 ? 105 GLU I OE2 1 
ATOM 6502 N N   . VAL D 2 100 ? 185.748 181.917 173.872 1.00 276.39 ? 106 VAL I N   1 
ATOM 6503 C CA  . VAL D 2 100 ? 184.406 182.267 173.432 1.00 276.39 ? 106 VAL I CA  1 
ATOM 6504 C C   . VAL D 2 100 ? 183.325 181.469 174.158 1.00 276.39 ? 106 VAL I C   1 
ATOM 6505 O O   . VAL D 2 100 ? 182.144 181.853 174.094 1.00 276.39 ? 106 VAL I O   1 
ATOM 6506 C CB  . VAL D 2 100 ? 184.278 182.094 171.900 1.00 276.39 ? 106 VAL I CB  1 
ATOM 6507 C CG1 . VAL D 2 100 ? 182.887 182.435 171.383 1.00 276.39 ? 106 VAL I CG1 1 
ATOM 6508 C CG2 . VAL D 2 100 ? 185.328 182.928 171.180 1.00 276.39 ? 106 VAL I CG2 1 
ATOM 6509 N N   . CYS D 2 101 ? 183.680 180.434 174.927 1.00 309.35 ? 107 CYS I N   1 
ATOM 6510 C CA  . CYS D 2 101 ? 182.684 179.558 175.542 1.00 309.35 ? 107 CYS I CA  1 
ATOM 6511 C C   . CYS D 2 101 ? 181.859 180.232 176.625 1.00 309.35 ? 107 CYS I C   1 
ATOM 6512 O O   . CYS D 2 101 ? 182.076 179.988 177.815 1.00 309.35 ? 107 CYS I O   1 
ATOM 6513 C CB  . CYS D 2 101 ? 183.340 178.325 176.173 1.00 309.35 ? 107 CYS I CB  1 
ATOM 6514 S SG  . CYS D 2 101 ? 183.614 176.929 175.118 1.00 309.35 ? 107 CYS I SG  1 
ATOM 6515 N N   . LYS D 2 102 ? 180.890 181.040 176.220 1.00 282.41 ? 108 LYS I N   1 
ATOM 6516 C CA  . LYS D 2 102 ? 179.960 181.656 177.144 1.00 282.41 ? 108 LYS I CA  1 
ATOM 6517 C C   . LYS D 2 102 ? 178.503 181.574 176.718 1.00 282.41 ? 108 LYS I C   1 
ATOM 6518 O O   . LYS D 2 102 ? 177.631 181.747 177.573 1.00 282.41 ? 108 LYS I O   1 
ATOM 6519 C CB  . LYS D 2 102 ? 180.338 183.124 177.382 1.00 282.41 ? 108 LYS I CB  1 
ATOM 6520 C CG  . LYS D 2 102 ? 181.431 183.362 178.439 1.00 282.41 ? 108 LYS I CG  1 
ATOM 6521 C CD  . LYS D 2 102 ? 182.826 182.986 177.968 1.00 282.41 ? 108 LYS I CD  1 
ATOM 6522 C CE  . LYS D 2 102 ? 183.337 183.916 176.901 1.00 282.41 ? 108 LYS I CE  1 
ATOM 6523 N NZ  . LYS D 2 102 ? 184.729 183.582 176.501 1.00 282.41 ? 108 LYS I NZ  1 
ATOM 6524 N N   . CYS D 2 103 ? 178.212 181.384 175.429 1.00 252.52 ? 109 CYS I N   1 
ATOM 6525 C CA  . CYS D 2 103 ? 176.898 181.048 174.873 1.00 252.52 ? 109 CYS I CA  1 
ATOM 6526 C C   . CYS D 2 103 ? 175.814 182.068 175.205 1.00 252.52 ? 109 CYS I C   1 
ATOM 6527 O O   . CYS D 2 103 ? 174.646 181.894 174.837 1.00 252.52 ? 109 CYS I O   1 
ATOM 6528 C CB  . CYS D 2 103 ? 176.454 179.649 175.305 1.00 252.52 ? 109 CYS I CB  1 
ATOM 6529 S SG  . CYS D 2 103 ? 176.067 179.371 177.054 1.00 252.52 ? 109 CYS I SG  1 
ATOM 6530 N N   . VAL D 2 104 ? 176.189 183.131 175.907 1.00 248.09 ? 110 VAL I N   1 
ATOM 6531 C CA  . VAL D 2 104 ? 175.356 184.315 176.074 1.00 248.09 ? 110 VAL I CA  1 
ATOM 6532 C C   . VAL D 2 104 ? 176.231 185.499 175.693 1.00 248.09 ? 110 VAL I C   1 
ATOM 6533 O O   . VAL D 2 104 ? 176.118 186.589 176.267 1.00 248.09 ? 110 VAL I O   1 
ATOM 6534 C CB  . VAL D 2 104 ? 174.799 184.432 177.503 1.00 248.09 ? 110 VAL I CB  1 
ATOM 6535 C CG1 . VAL D 2 104 ? 173.744 183.365 177.732 1.00 248.09 ? 110 VAL I CG1 1 
ATOM 6536 C CG2 . VAL D 2 104 ? 175.910 184.259 178.502 1.00 248.09 ? 110 VAL I CG2 1 
ATOM 6537 N N   . GLU D 2 105 ? 177.136 185.259 174.740 1.00 222.59 ? 111 GLU I N   1 
ATOM 6538 C CA  . GLU D 2 105 ? 178.159 186.203 174.309 1.00 222.59 ? 111 GLU I CA  1 
ATOM 6539 C C   . GLU D 2 105 ? 179.137 186.445 175.448 1.00 222.59 ? 111 GLU I C   1 
ATOM 6540 O O   . GLU D 2 105 ? 180.265 185.941 175.417 1.00 222.59 ? 111 GLU I O   1 
ATOM 6541 C CB  . GLU D 2 105 ? 177.537 187.512 173.818 1.00 222.59 ? 111 GLU I CB  1 
ATOM 6542 C CG  . GLU D 2 105 ? 176.979 187.423 172.411 1.00 222.59 ? 111 GLU I CG  1 
ATOM 6543 C CD  . GLU D 2 105 ? 175.770 186.515 172.333 1.00 222.59 ? 111 GLU I CD  1 
ATOM 6544 O OE1 . GLU D 2 105 ? 174.699 186.909 172.839 1.00 222.59 ? 111 GLU I OE1 1 
ATOM 6545 O OE2 . GLU D 2 105 ? 175.890 185.402 171.779 1.00 222.59 ? 111 GLU I OE2 1 
ATOM 6546 N N   . PHE D 2 106 ? 178.699 187.194 176.461 1.00 265.00 ? 112 PHE I N   1 
ATOM 6547 C CA  . PHE D 2 106 ? 179.530 187.546 177.608 1.00 265.00 ? 112 PHE I CA  1 
ATOM 6548 C C   . PHE D 2 106 ? 180.899 188.022 177.148 1.00 265.00 ? 112 PHE I C   1 
ATOM 6549 O O   . PHE D 2 106 ? 180.998 189.001 176.403 1.00 265.00 ? 112 PHE I O   1 
ATOM 6550 C CB  . PHE D 2 106 ? 179.658 186.367 178.574 1.00 265.00 ? 112 PHE I CB  1 
ATOM 6551 C CG  . PHE D 2 106 ? 178.541 186.281 179.583 1.00 265.00 ? 112 PHE I CG  1 
ATOM 6552 C CD1 . PHE D 2 106 ? 177.460 187.145 179.516 1.00 265.00 ? 112 PHE I CD1 1 
ATOM 6553 C CD2 . PHE D 2 106 ? 178.570 185.331 180.594 1.00 265.00 ? 112 PHE I CD2 1 
ATOM 6554 C CE1 . PHE D 2 106 ? 176.434 187.068 180.439 1.00 265.00 ? 112 PHE I CE1 1 
ATOM 6555 C CE2 . PHE D 2 106 ? 177.542 185.249 181.520 1.00 265.00 ? 112 PHE I CE2 1 
ATOM 6556 C CZ  . PHE D 2 106 ? 176.473 186.119 181.441 1.00 265.00 ? 112 PHE I CZ  1 
ATOM 6557 N N   . LEU D 2 107 ? 181.957 187.373 177.634 1.00 251.69 ? 113 LEU I N   1 
ATOM 6558 C CA  . LEU D 2 107 ? 183.291 187.491 177.055 1.00 251.69 ? 113 LEU I CA  1 
ATOM 6559 C C   . LEU D 2 107 ? 183.884 188.883 177.249 1.00 251.69 ? 113 LEU I C   1 
ATOM 6560 O O   . LEU D 2 107 ? 185.073 189.092 176.998 1.00 251.69 ? 113 LEU I O   1 
ATOM 6561 C CB  . LEU D 2 107 ? 183.229 187.165 175.557 1.00 251.69 ? 113 LEU I CB  1 
ATOM 6562 C CG  . LEU D 2 107 ? 184.467 186.884 174.707 1.00 251.69 ? 113 LEU I CG  1 
ATOM 6563 C CD1 . LEU D 2 107 ? 184.068 185.887 173.650 1.00 251.69 ? 113 LEU I CD1 1 
ATOM 6564 C CD2 . LEU D 2 107 ? 185.051 188.124 174.059 1.00 251.69 ? 113 LEU I CD2 1 
ATOM 6565 N N   . SER D 2 108 ? 183.082 189.838 177.715 1.00 244.04 ? 114 SER I N   1 
ATOM 6566 C CA  . SER D 2 108 ? 183.487 191.237 177.713 1.00 244.04 ? 114 SER I CA  1 
ATOM 6567 C C   . SER D 2 108 ? 183.782 191.747 179.118 1.00 244.04 ? 114 SER I C   1 
ATOM 6568 O O   . SER D 2 108 ? 184.886 192.228 179.383 1.00 244.04 ? 114 SER I O   1 
ATOM 6569 C CB  . SER D 2 108 ? 182.402 192.088 177.045 1.00 244.04 ? 114 SER I CB  1 
ATOM 6570 O OG  . SER D 2 108 ? 182.199 191.684 175.705 1.00 244.04 ? 114 SER I OG  1 
ATOM 6571 N N   . VAL D 2 109 ? 182.813 191.645 180.025 1.00 266.51 ? 115 VAL I N   1 
ATOM 6572 C CA  . VAL D 2 109 ? 183.031 192.051 181.410 1.00 266.51 ? 115 VAL I CA  1 
ATOM 6573 C C   . VAL D 2 109 ? 182.744 190.879 182.345 1.00 266.51 ? 115 VAL I C   1 
ATOM 6574 O O   . VAL D 2 109 ? 183.615 190.494 183.133 1.00 266.51 ? 115 VAL I O   1 
ATOM 6575 C CB  . VAL D 2 109 ? 182.205 193.299 181.781 1.00 266.51 ? 115 VAL I CB  1 
ATOM 6576 C CG1 . VAL D 2 109 ? 182.354 193.609 183.257 1.00 266.51 ? 115 VAL I CG1 1 
ATOM 6577 C CG2 . VAL D 2 109 ? 182.644 194.487 180.948 1.00 266.51 ? 115 VAL I CG2 1 
ATOM 6578 N N   . HIS D 2 110 ? 181.545 190.290 182.288 1.00 277.58 ? 116 HIS I N   1 
ATOM 6579 C CA  . HIS D 2 110 ? 180.275 190.551 181.604 1.00 277.58 ? 116 HIS I CA  1 
ATOM 6580 C C   . HIS D 2 110 ? 179.120 190.273 182.553 1.00 277.58 ? 116 HIS I C   1 
ATOM 6581 O O   . HIS D 2 110 ? 178.131 189.651 182.172 1.00 277.58 ? 116 HIS I O   1 
ATOM 6582 C CB  . HIS D 2 110 ? 180.127 189.689 180.356 1.00 277.58 ? 116 HIS I CB  1 
ATOM 6583 C CG  . HIS D 2 110 ? 179.226 190.276 179.315 1.00 277.58 ? 116 HIS I CG  1 
ATOM 6584 N ND1 . HIS D 2 110 ? 179.700 190.813 178.139 1.00 277.58 ? 116 HIS I ND1 1 
ATOM 6585 C CD2 . HIS D 2 110 ? 177.880 190.412 179.275 1.00 277.58 ? 116 HIS I CD2 1 
ATOM 6586 C CE1 . HIS D 2 110 ? 178.684 191.244 177.414 1.00 277.58 ? 116 HIS I CE1 1 
ATOM 6587 N NE2 . HIS D 2 110 ? 177.568 191.015 178.082 1.00 277.58 ? 116 HIS I NE2 1 
ATOM 6588 N N   . ASN D 2 111 ? 179.258 190.724 183.795 1.00 319.38 ? 117 ASN I N   1 
ATOM 6589 C CA  . ASN D 2 111 ? 178.298 190.400 184.846 1.00 319.38 ? 117 ASN I CA  1 
ATOM 6590 C C   . ASN D 2 111 ? 176.954 191.040 184.520 1.00 319.38 ? 117 ASN I C   1 
ATOM 6591 O O   . ASN D 2 111 ? 176.787 192.256 184.627 1.00 319.38 ? 117 ASN I O   1 
ATOM 6592 C CB  . ASN D 2 111 ? 178.822 190.875 186.196 1.00 319.38 ? 117 ASN I CB  1 
ATOM 6593 C CG  . ASN D 2 111 ? 178.199 190.129 187.357 1.00 319.38 ? 117 ASN I CG  1 
ATOM 6594 O OD1 . ASN D 2 111 ? 177.143 189.513 187.221 1.00 319.38 ? 117 ASN I OD1 1 
ATOM 6595 N ND2 . ASN D 2 111 ? 178.853 190.185 188.512 1.00 319.38 ? 117 ASN I ND2 1 
ATOM 6596 N N   . ILE D 2 112 ? 175.990 190.219 184.119 1.00 329.57 ? 118 ILE I N   1 
ATOM 6597 C CA  . ILE D 2 112 ? 174.643 190.701 183.847 1.00 329.57 ? 118 ILE I CA  1 
ATOM 6598 C C   . ILE D 2 112 ? 173.714 190.272 184.972 1.00 329.57 ? 118 ILE I C   1 
ATOM 6599 O O   . ILE D 2 112 ? 174.161 189.719 185.976 1.00 329.57 ? 118 ILE I O   1 
ATOM 6600 C CB  . ILE D 2 112 ? 174.123 190.202 182.490 1.00 329.57 ? 118 ILE I CB  1 
ATOM 6601 C CG1 . ILE D 2 112 ? 173.997 188.679 182.493 1.00 329.57 ? 118 ILE I CG1 1 
ATOM 6602 C CG2 . ILE D 2 112 ? 175.032 190.669 181.364 1.00 329.57 ? 118 ILE I CG2 1 
ATOM 6603 C CD1 . ILE D 2 112 ? 173.281 188.133 181.284 1.00 329.57 ? 118 ILE I CD1 1 
# 
