data_8UA6
# 
_entry.id   8UA6 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UA6         pdb_00008ua6 10.2210/pdb8ua6/pdb 
WWPDB D_1000277644 ?            ?                   
EMDB  EMD-42051    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-13 
3 'Structure model' 1 2 2024-11-20 
4 'Structure model' 1 3 2025-01-08 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 3 'Structure model' 'Database references' 
5 4 'Structure model' 'Data collection'     
6 4 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' citation        
5 3 'Structure model' em_admin        
6 4 'Structure model' citation        
7 4 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.journal_abbrev'          
2  2 'Structure model' '_citation.journal_id_ASTM'         
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.pdbx_database_id_DOI'    
6  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
7  2 'Structure model' '_citation.title'                   
8  2 'Structure model' '_em_admin.last_update'             
9  3 'Structure model' '_citation.country'                 
10 3 'Structure model' '_citation.journal_abbrev'          
11 3 'Structure model' '_citation.journal_id_ASTM'         
12 3 'Structure model' '_citation.journal_id_CSD'          
13 3 'Structure model' '_citation.journal_id_ISSN'         
14 3 'Structure model' '_citation.pdbx_database_id_PubMed' 
15 3 'Structure model' '_citation.title'                   
16 3 'Structure model' '_em_admin.last_update'             
17 4 'Structure model' '_citation.journal_volume'          
18 4 'Structure model' '_citation.page_first'              
19 4 'Structure model' '_citation.page_last'               
20 4 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UA6 
_pdbx_database_status.recvd_initial_deposition_date   2023-09-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM Structure of SCF-FBOX22-BACH1BTB' 
_pdbx_database_related.db_id          EMD-42051 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              nzheng@uw.edu 
_pdbx_contact_author.name_first         Zheng 
_pdbx_contact_author.name_last          Ning 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1039-1581 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Shi, H.'   1 0000-0003-2428-2500 
'Cao, S.'   2 0000-0003-1201-4963 
'Zheng, N.' 3 0000-0002-1039-1581 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Cell 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1097-4172 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            187 
_citation.language                  ? 
_citation.page_first                7568 
_citation.page_last                 7584.e22 
_citation.title                     
'Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.cell.2024.10.012 
_citation.pdbx_database_id_PubMed   39504958 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cao, S.'        1  ? 
primary 'Garcia, S.F.'   2  ? 
primary 'Shi, H.'        3  ? 
primary 'James, E.I.'    4  ? 
primary 'Kito, Y.'       5  ? 
primary 'Shi, H.'        6  ? 
primary 'Mao, H.'        7  ? 
primary 'Kaisari, S.'    8  ? 
primary 'Rona, G.'       9  ? 
primary 'Deng, S.'       10 ? 
primary 'Goldberg, H.V.' 11 ? 
primary 'Ponce, J.'      12 ? 
primary 'Ueberheide, B.' 13 ? 
primary 'Lignitto, L.'   14 ? 
primary 'Guttman, M.'    15 ? 
primary 'Pagano, M.'     16 ? 
primary 'Zheng, N.'      17 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'F-box only protein 22'                 44562.270 1 ? ? ?                                 ? 
2 polymer man 'Transcription regulator protein BACH1' 13839.761 2 ? ? 'BTB domain (UNP residues 7-128)' ? 
3 polymer man 'S-phase kinase-associated protein 1'   18082.326 1 ? ? ?                                 ? 
4 polymer man Cullin-1                                88501.945 1 ? ? ?                                 ? 
# 
_entity_name_com.entity_id   4 
_entity_name_com.name        CUL-1 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MEPVGCCGECRGSSVDPRSTFVLSNLAEVVERVLTFLPAKALLRVACVCRLWRECVRRVLRTHRSVTWISAGLAEAGHLE
GHCLVRVVAEELENVRILPHTVLYMADSETFISLEECRGHKRARKRTSMETALALEKLFPKQCQVLGIVTPGIVVTPMGS
GSNRPQEIEIGESGFALLFPQIEGIKIQPFHFIKDPKNLTLERHQLTEVGLLDNPELRVVLVFGYNCCKVGASNYLQQVV
STFSDMNIILAGGQVDNLSSLTSEKNPLDIDASGVVGLSFSGHRIQSATVLLNEDVSDEKTAEAAMQRLKAANIPEHNTI
GFMFACVGRGFQYYRAKGNVEADAFRKFFPSVPLFGFFGNGEIGCDRIVTGNFILRKCNEVKDDDLFHSYTTIMALIHLG
SSK
;
;MEPVGCCGECRGSSVDPRSTFVLSNLAEVVERVLTFLPAKALLRVACVCRLWRECVRRVLRTHRSVTWISAGLAEAGHLE
GHCLVRVVAEELENVRILPHTVLYMADSETFISLEECRGHKRARKRTSMETALALEKLFPKQCQVLGIVTPGIVVTPMGS
GSNRPQEIEIGESGFALLFPQIEGIKIQPFHFIKDPKNLTLERHQLTEVGLLDNPELRVVLVFGYNCCKVGASNYLQQVV
STFSDMNIILAGGQVDNLSSLTSEKNPLDIDASGVVGLSFSGHRIQSATVLLNEDVSDEKTAEAAMQRLKAANIPEHNTI
GFMFACVGRGFQYYRAKGNVEADAFRKFFPSVPLFGFFGNGEIGCDRIVTGNFILRKCNEVKDDDLFHSYTTIMALIHLG
SSK
;
C   ? 
2 'polypeptide(L)' no no 
;SVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKF
;
;SVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKF
;
D,E ? 
3 'polypeptide(L)' no no 
;MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEK
RTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVGSTQFCL
;
;MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEK
RTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVGSTQFCL
;
B   ? 
4 'polypeptide(L)' no no 
;KQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRL
KEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLF
RPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFL
QQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDG
LGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMA
QSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKL
KQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYAS
RHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLE
DENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLG
EVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA
;
;KQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRL
KEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLF
RPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFL
QQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDG
LGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMA
QSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKL
KQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYAS
RHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLE
DENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLG
EVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA
;
A   ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLU n 
1 3   PRO n 
1 4   VAL n 
1 5   GLY n 
1 6   CYS n 
1 7   CYS n 
1 8   GLY n 
1 9   GLU n 
1 10  CYS n 
1 11  ARG n 
1 12  GLY n 
1 13  SER n 
1 14  SER n 
1 15  VAL n 
1 16  ASP n 
1 17  PRO n 
1 18  ARG n 
1 19  SER n 
1 20  THR n 
1 21  PHE n 
1 22  VAL n 
1 23  LEU n 
1 24  SER n 
1 25  ASN n 
1 26  LEU n 
1 27  ALA n 
1 28  GLU n 
1 29  VAL n 
1 30  VAL n 
1 31  GLU n 
1 32  ARG n 
1 33  VAL n 
1 34  LEU n 
1 35  THR n 
1 36  PHE n 
1 37  LEU n 
1 38  PRO n 
1 39  ALA n 
1 40  LYS n 
1 41  ALA n 
1 42  LEU n 
1 43  LEU n 
1 44  ARG n 
1 45  VAL n 
1 46  ALA n 
1 47  CYS n 
1 48  VAL n 
1 49  CYS n 
1 50  ARG n 
1 51  LEU n 
1 52  TRP n 
1 53  ARG n 
1 54  GLU n 
1 55  CYS n 
1 56  VAL n 
1 57  ARG n 
1 58  ARG n 
1 59  VAL n 
1 60  LEU n 
1 61  ARG n 
1 62  THR n 
1 63  HIS n 
1 64  ARG n 
1 65  SER n 
1 66  VAL n 
1 67  THR n 
1 68  TRP n 
1 69  ILE n 
1 70  SER n 
1 71  ALA n 
1 72  GLY n 
1 73  LEU n 
1 74  ALA n 
1 75  GLU n 
1 76  ALA n 
1 77  GLY n 
1 78  HIS n 
1 79  LEU n 
1 80  GLU n 
1 81  GLY n 
1 82  HIS n 
1 83  CYS n 
1 84  LEU n 
1 85  VAL n 
1 86  ARG n 
1 87  VAL n 
1 88  VAL n 
1 89  ALA n 
1 90  GLU n 
1 91  GLU n 
1 92  LEU n 
1 93  GLU n 
1 94  ASN n 
1 95  VAL n 
1 96  ARG n 
1 97  ILE n 
1 98  LEU n 
1 99  PRO n 
1 100 HIS n 
1 101 THR n 
1 102 VAL n 
1 103 LEU n 
1 104 TYR n 
1 105 MET n 
1 106 ALA n 
1 107 ASP n 
1 108 SER n 
1 109 GLU n 
1 110 THR n 
1 111 PHE n 
1 112 ILE n 
1 113 SER n 
1 114 LEU n 
1 115 GLU n 
1 116 GLU n 
1 117 CYS n 
1 118 ARG n 
1 119 GLY n 
1 120 HIS n 
1 121 LYS n 
1 122 ARG n 
1 123 ALA n 
1 124 ARG n 
1 125 LYS n 
1 126 ARG n 
1 127 THR n 
1 128 SER n 
1 129 MET n 
1 130 GLU n 
1 131 THR n 
1 132 ALA n 
1 133 LEU n 
1 134 ALA n 
1 135 LEU n 
1 136 GLU n 
1 137 LYS n 
1 138 LEU n 
1 139 PHE n 
1 140 PRO n 
1 141 LYS n 
1 142 GLN n 
1 143 CYS n 
1 144 GLN n 
1 145 VAL n 
1 146 LEU n 
1 147 GLY n 
1 148 ILE n 
1 149 VAL n 
1 150 THR n 
1 151 PRO n 
1 152 GLY n 
1 153 ILE n 
1 154 VAL n 
1 155 VAL n 
1 156 THR n 
1 157 PRO n 
1 158 MET n 
1 159 GLY n 
1 160 SER n 
1 161 GLY n 
1 162 SER n 
1 163 ASN n 
1 164 ARG n 
1 165 PRO n 
1 166 GLN n 
1 167 GLU n 
1 168 ILE n 
1 169 GLU n 
1 170 ILE n 
1 171 GLY n 
1 172 GLU n 
1 173 SER n 
1 174 GLY n 
1 175 PHE n 
1 176 ALA n 
1 177 LEU n 
1 178 LEU n 
1 179 PHE n 
1 180 PRO n 
1 181 GLN n 
1 182 ILE n 
1 183 GLU n 
1 184 GLY n 
1 185 ILE n 
1 186 LYS n 
1 187 ILE n 
1 188 GLN n 
1 189 PRO n 
1 190 PHE n 
1 191 HIS n 
1 192 PHE n 
1 193 ILE n 
1 194 LYS n 
1 195 ASP n 
1 196 PRO n 
1 197 LYS n 
1 198 ASN n 
1 199 LEU n 
1 200 THR n 
1 201 LEU n 
1 202 GLU n 
1 203 ARG n 
1 204 HIS n 
1 205 GLN n 
1 206 LEU n 
1 207 THR n 
1 208 GLU n 
1 209 VAL n 
1 210 GLY n 
1 211 LEU n 
1 212 LEU n 
1 213 ASP n 
1 214 ASN n 
1 215 PRO n 
1 216 GLU n 
1 217 LEU n 
1 218 ARG n 
1 219 VAL n 
1 220 VAL n 
1 221 LEU n 
1 222 VAL n 
1 223 PHE n 
1 224 GLY n 
1 225 TYR n 
1 226 ASN n 
1 227 CYS n 
1 228 CYS n 
1 229 LYS n 
1 230 VAL n 
1 231 GLY n 
1 232 ALA n 
1 233 SER n 
1 234 ASN n 
1 235 TYR n 
1 236 LEU n 
1 237 GLN n 
1 238 GLN n 
1 239 VAL n 
1 240 VAL n 
1 241 SER n 
1 242 THR n 
1 243 PHE n 
1 244 SER n 
1 245 ASP n 
1 246 MET n 
1 247 ASN n 
1 248 ILE n 
1 249 ILE n 
1 250 LEU n 
1 251 ALA n 
1 252 GLY n 
1 253 GLY n 
1 254 GLN n 
1 255 VAL n 
1 256 ASP n 
1 257 ASN n 
1 258 LEU n 
1 259 SER n 
1 260 SER n 
1 261 LEU n 
1 262 THR n 
1 263 SER n 
1 264 GLU n 
1 265 LYS n 
1 266 ASN n 
1 267 PRO n 
1 268 LEU n 
1 269 ASP n 
1 270 ILE n 
1 271 ASP n 
1 272 ALA n 
1 273 SER n 
1 274 GLY n 
1 275 VAL n 
1 276 VAL n 
1 277 GLY n 
1 278 LEU n 
1 279 SER n 
1 280 PHE n 
1 281 SER n 
1 282 GLY n 
1 283 HIS n 
1 284 ARG n 
1 285 ILE n 
1 286 GLN n 
1 287 SER n 
1 288 ALA n 
1 289 THR n 
1 290 VAL n 
1 291 LEU n 
1 292 LEU n 
1 293 ASN n 
1 294 GLU n 
1 295 ASP n 
1 296 VAL n 
1 297 SER n 
1 298 ASP n 
1 299 GLU n 
1 300 LYS n 
1 301 THR n 
1 302 ALA n 
1 303 GLU n 
1 304 ALA n 
1 305 ALA n 
1 306 MET n 
1 307 GLN n 
1 308 ARG n 
1 309 LEU n 
1 310 LYS n 
1 311 ALA n 
1 312 ALA n 
1 313 ASN n 
1 314 ILE n 
1 315 PRO n 
1 316 GLU n 
1 317 HIS n 
1 318 ASN n 
1 319 THR n 
1 320 ILE n 
1 321 GLY n 
1 322 PHE n 
1 323 MET n 
1 324 PHE n 
1 325 ALA n 
1 326 CYS n 
1 327 VAL n 
1 328 GLY n 
1 329 ARG n 
1 330 GLY n 
1 331 PHE n 
1 332 GLN n 
1 333 TYR n 
1 334 TYR n 
1 335 ARG n 
1 336 ALA n 
1 337 LYS n 
1 338 GLY n 
1 339 ASN n 
1 340 VAL n 
1 341 GLU n 
1 342 ALA n 
1 343 ASP n 
1 344 ALA n 
1 345 PHE n 
1 346 ARG n 
1 347 LYS n 
1 348 PHE n 
1 349 PHE n 
1 350 PRO n 
1 351 SER n 
1 352 VAL n 
1 353 PRO n 
1 354 LEU n 
1 355 PHE n 
1 356 GLY n 
1 357 PHE n 
1 358 PHE n 
1 359 GLY n 
1 360 ASN n 
1 361 GLY n 
1 362 GLU n 
1 363 ILE n 
1 364 GLY n 
1 365 CYS n 
1 366 ASP n 
1 367 ARG n 
1 368 ILE n 
1 369 VAL n 
1 370 THR n 
1 371 GLY n 
1 372 ASN n 
1 373 PHE n 
1 374 ILE n 
1 375 LEU n 
1 376 ARG n 
1 377 LYS n 
1 378 CYS n 
1 379 ASN n 
1 380 GLU n 
1 381 VAL n 
1 382 LYS n 
1 383 ASP n 
1 384 ASP n 
1 385 ASP n 
1 386 LEU n 
1 387 PHE n 
1 388 HIS n 
1 389 SER n 
1 390 TYR n 
1 391 THR n 
1 392 THR n 
1 393 ILE n 
1 394 MET n 
1 395 ALA n 
1 396 LEU n 
1 397 ILE n 
1 398 HIS n 
1 399 LEU n 
1 400 GLY n 
1 401 SER n 
1 402 SER n 
1 403 LYS n 
2 1   SER n 
2 2   VAL n 
2 3   PHE n 
2 4   ALA n 
2 5   TYR n 
2 6   GLU n 
2 7   SER n 
2 8   SER n 
2 9   VAL n 
2 10  HIS n 
2 11  SER n 
2 12  THR n 
2 13  ASN n 
2 14  VAL n 
2 15  LEU n 
2 16  LEU n 
2 17  SER n 
2 18  LEU n 
2 19  ASN n 
2 20  ASP n 
2 21  GLN n 
2 22  ARG n 
2 23  LYS n 
2 24  LYS n 
2 25  ASP n 
2 26  VAL n 
2 27  LEU n 
2 28  CYS n 
2 29  ASP n 
2 30  VAL n 
2 31  THR n 
2 32  ILE n 
2 33  PHE n 
2 34  VAL n 
2 35  GLU n 
2 36  GLY n 
2 37  GLN n 
2 38  ARG n 
2 39  PHE n 
2 40  ARG n 
2 41  ALA n 
2 42  HIS n 
2 43  ARG n 
2 44  SER n 
2 45  VAL n 
2 46  LEU n 
2 47  ALA n 
2 48  ALA n 
2 49  CYS n 
2 50  SER n 
2 51  SER n 
2 52  TYR n 
2 53  PHE n 
2 54  HIS n 
2 55  SER n 
2 56  ARG n 
2 57  ILE n 
2 58  VAL n 
2 59  GLY n 
2 60  GLN n 
2 61  ALA n 
2 62  ASP n 
2 63  GLY n 
2 64  GLU n 
2 65  LEU n 
2 66  ASN n 
2 67  ILE n 
2 68  THR n 
2 69  LEU n 
2 70  PRO n 
2 71  GLU n 
2 72  GLU n 
2 73  VAL n 
2 74  THR n 
2 75  VAL n 
2 76  LYS n 
2 77  GLY n 
2 78  PHE n 
2 79  GLU n 
2 80  PRO n 
2 81  LEU n 
2 82  ILE n 
2 83  GLN n 
2 84  PHE n 
2 85  ALA n 
2 86  TYR n 
2 87  THR n 
2 88  ALA n 
2 89  LYS n 
2 90  LEU n 
2 91  ILE n 
2 92  LEU n 
2 93  SER n 
2 94  LYS n 
2 95  GLU n 
2 96  ASN n 
2 97  VAL n 
2 98  ASP n 
2 99  GLU n 
2 100 VAL n 
2 101 CYS n 
2 102 LYS n 
2 103 CYS n 
2 104 VAL n 
2 105 GLU n 
2 106 PHE n 
2 107 LEU n 
2 108 SER n 
2 109 VAL n 
2 110 HIS n 
2 111 ASN n 
2 112 ILE n 
2 113 GLU n 
2 114 GLU n 
2 115 SER n 
2 116 CYS n 
2 117 PHE n 
2 118 GLN n 
2 119 PHE n 
2 120 LEU n 
2 121 LYS n 
2 122 PHE n 
3 1   MET n 
3 2   PRO n 
3 3   SER n 
3 4   ILE n 
3 5   LYS n 
3 6   LEU n 
3 7   GLN n 
3 8   SER n 
3 9   SER n 
3 10  ASP n 
3 11  GLY n 
3 12  GLU n 
3 13  ILE n 
3 14  PHE n 
3 15  GLU n 
3 16  VAL n 
3 17  ASP n 
3 18  VAL n 
3 19  GLU n 
3 20  ILE n 
3 21  ALA n 
3 22  LYS n 
3 23  GLN n 
3 24  SER n 
3 25  VAL n 
3 26  THR n 
3 27  ILE n 
3 28  LYS n 
3 29  THR n 
3 30  MET n 
3 31  LEU n 
3 32  GLU n 
3 33  ASP n 
3 34  LEU n 
3 35  GLY n 
3 36  MET n 
3 37  ASP n 
3 38  ASP n 
3 39  GLU n 
3 40  GLY n 
3 41  ASP n 
3 42  ASP n 
3 43  ASP n 
3 44  PRO n 
3 45  VAL n 
3 46  PRO n 
3 47  LEU n 
3 48  PRO n 
3 49  ASN n 
3 50  VAL n 
3 51  ASN n 
3 52  ALA n 
3 53  ALA n 
3 54  ILE n 
3 55  LEU n 
3 56  LYS n 
3 57  LYS n 
3 58  VAL n 
3 59  ILE n 
3 60  GLN n 
3 61  TRP n 
3 62  CYS n 
3 63  THR n 
3 64  HIS n 
3 65  HIS n 
3 66  LYS n 
3 67  ASP n 
3 68  ASP n 
3 69  PRO n 
3 70  PRO n 
3 71  PRO n 
3 72  PRO n 
3 73  GLU n 
3 74  ASP n 
3 75  ASP n 
3 76  GLU n 
3 77  ASN n 
3 78  LYS n 
3 79  GLU n 
3 80  LYS n 
3 81  ARG n 
3 82  THR n 
3 83  ASP n 
3 84  ASP n 
3 85  ILE n 
3 86  PRO n 
3 87  VAL n 
3 88  TRP n 
3 89  ASP n 
3 90  GLN n 
3 91  GLU n 
3 92  PHE n 
3 93  LEU n 
3 94  LYS n 
3 95  VAL n 
3 96  ASP n 
3 97  GLN n 
3 98  GLY n 
3 99  THR n 
3 100 LEU n 
3 101 PHE n 
3 102 GLU n 
3 103 LEU n 
3 104 ILE n 
3 105 LEU n 
3 106 ALA n 
3 107 ALA n 
3 108 ASN n 
3 109 TYR n 
3 110 LEU n 
3 111 ASP n 
3 112 ILE n 
3 113 LYS n 
3 114 GLY n 
3 115 LEU n 
3 116 LEU n 
3 117 ASP n 
3 118 VAL n 
3 119 THR n 
3 120 CYS n 
3 121 LYS n 
3 122 THR n 
3 123 VAL n 
3 124 ALA n 
3 125 ASN n 
3 126 MET n 
3 127 ILE n 
3 128 LYS n 
3 129 GLY n 
3 130 LYS n 
3 131 THR n 
3 132 PRO n 
3 133 GLU n 
3 134 GLU n 
3 135 ILE n 
3 136 ARG n 
3 137 LYS n 
3 138 THR n 
3 139 PHE n 
3 140 ASN n 
3 141 ILE n 
3 142 LYS n 
3 143 ASN n 
3 144 ASP n 
3 145 PHE n 
3 146 THR n 
3 147 GLU n 
3 148 GLU n 
3 149 GLU n 
3 150 GLU n 
3 151 ALA n 
3 152 GLN n 
3 153 VAL n 
3 154 GLY n 
3 155 SER n 
3 156 THR n 
3 157 GLN n 
3 158 PHE n 
3 159 CYS n 
3 160 LEU n 
4 1   LYS n 
4 2   GLN n 
4 3   ILE n 
4 4   GLY n 
4 5   LEU n 
4 6   ASP n 
4 7   GLN n 
4 8   ILE n 
4 9   TRP n 
4 10  ASP n 
4 11  ASP n 
4 12  LEU n 
4 13  ARG n 
4 14  ALA n 
4 15  GLY n 
4 16  ILE n 
4 17  GLN n 
4 18  GLN n 
4 19  VAL n 
4 20  TYR n 
4 21  THR n 
4 22  ARG n 
4 23  GLN n 
4 24  SER n 
4 25  MET n 
4 26  ALA n 
4 27  LYS n 
4 28  SER n 
4 29  ARG n 
4 30  TYR n 
4 31  MET n 
4 32  GLU n 
4 33  LEU n 
4 34  TYR n 
4 35  THR n 
4 36  HIS n 
4 37  VAL n 
4 38  TYR n 
4 39  ASN n 
4 40  TYR n 
4 41  CYS n 
4 42  THR n 
4 43  SER n 
4 44  VAL n 
4 45  HIS n 
4 46  GLN n 
4 47  SER n 
4 48  ASN n 
4 49  GLN n 
4 50  ALA n 
4 51  ARG n 
4 52  GLY n 
4 53  ALA n 
4 54  GLY n 
4 55  VAL n 
4 56  PRO n 
4 57  PRO n 
4 58  SER n 
4 59  LYS n 
4 60  SER n 
4 61  LYS n 
4 62  LYS n 
4 63  GLY n 
4 64  GLN n 
4 65  THR n 
4 66  PRO n 
4 67  GLY n 
4 68  GLY n 
4 69  ALA n 
4 70  GLN n 
4 71  PHE n 
4 72  VAL n 
4 73  GLY n 
4 74  LEU n 
4 75  GLU n 
4 76  LEU n 
4 77  TYR n 
4 78  LYS n 
4 79  ARG n 
4 80  LEU n 
4 81  LYS n 
4 82  GLU n 
4 83  PHE n 
4 84  LEU n 
4 85  LYS n 
4 86  ASN n 
4 87  TYR n 
4 88  LEU n 
4 89  THR n 
4 90  ASN n 
4 91  LEU n 
4 92  LEU n 
4 93  LYS n 
4 94  ASP n 
4 95  GLY n 
4 96  GLU n 
4 97  ASP n 
4 98  LEU n 
4 99  MET n 
4 100 ASP n 
4 101 GLU n 
4 102 SER n 
4 103 VAL n 
4 104 LEU n 
4 105 LYS n 
4 106 PHE n 
4 107 TYR n 
4 108 THR n 
4 109 GLN n 
4 110 GLN n 
4 111 TRP n 
4 112 GLU n 
4 113 ASP n 
4 114 TYR n 
4 115 ARG n 
4 116 PHE n 
4 117 SER n 
4 118 SER n 
4 119 LYS n 
4 120 VAL n 
4 121 LEU n 
4 122 ASN n 
4 123 GLY n 
4 124 ILE n 
4 125 CYS n 
4 126 ALA n 
4 127 TYR n 
4 128 LEU n 
4 129 ASN n 
4 130 ARG n 
4 131 HIS n 
4 132 TRP n 
4 133 VAL n 
4 134 ARG n 
4 135 ARG n 
4 136 GLU n 
4 137 CYS n 
4 138 ASP n 
4 139 GLU n 
4 140 GLY n 
4 141 ARG n 
4 142 LYS n 
4 143 GLY n 
4 144 ILE n 
4 145 TYR n 
4 146 GLU n 
4 147 ILE n 
4 148 TYR n 
4 149 SER n 
4 150 LEU n 
4 151 ALA n 
4 152 LEU n 
4 153 VAL n 
4 154 THR n 
4 155 TRP n 
4 156 ARG n 
4 157 ASP n 
4 158 CYS n 
4 159 LEU n 
4 160 PHE n 
4 161 ARG n 
4 162 PRO n 
4 163 LEU n 
4 164 ASN n 
4 165 LYS n 
4 166 GLN n 
4 167 VAL n 
4 168 THR n 
4 169 ASN n 
4 170 ALA n 
4 171 VAL n 
4 172 LEU n 
4 173 LYS n 
4 174 LEU n 
4 175 ILE n 
4 176 GLU n 
4 177 LYS n 
4 178 GLU n 
4 179 ARG n 
4 180 ASN n 
4 181 GLY n 
4 182 GLU n 
4 183 THR n 
4 184 ILE n 
4 185 ASN n 
4 186 THR n 
4 187 ARG n 
4 188 LEU n 
4 189 ILE n 
4 190 SER n 
4 191 GLY n 
4 192 VAL n 
4 193 VAL n 
4 194 GLN n 
4 195 SER n 
4 196 TYR n 
4 197 VAL n 
4 198 GLU n 
4 199 LEU n 
4 200 GLY n 
4 201 LEU n 
4 202 ASN n 
4 203 GLU n 
4 204 ASP n 
4 205 ASP n 
4 206 ALA n 
4 207 PHE n 
4 208 ALA n 
4 209 LYS n 
4 210 GLY n 
4 211 PRO n 
4 212 THR n 
4 213 LEU n 
4 214 THR n 
4 215 VAL n 
4 216 TYR n 
4 217 LYS n 
4 218 GLU n 
4 219 SER n 
4 220 PHE n 
4 221 GLU n 
4 222 SER n 
4 223 GLN n 
4 224 PHE n 
4 225 LEU n 
4 226 ALA n 
4 227 ASP n 
4 228 THR n 
4 229 GLU n 
4 230 ARG n 
4 231 PHE n 
4 232 TYR n 
4 233 THR n 
4 234 ARG n 
4 235 GLU n 
4 236 SER n 
4 237 THR n 
4 238 GLU n 
4 239 PHE n 
4 240 LEU n 
4 241 GLN n 
4 242 GLN n 
4 243 ASN n 
4 244 PRO n 
4 245 VAL n 
4 246 THR n 
4 247 GLU n 
4 248 TYR n 
4 249 MET n 
4 250 LYS n 
4 251 LYS n 
4 252 ALA n 
4 253 GLU n 
4 254 ALA n 
4 255 ARG n 
4 256 LEU n 
4 257 LEU n 
4 258 GLU n 
4 259 GLU n 
4 260 GLN n 
4 261 ARG n 
4 262 ARG n 
4 263 VAL n 
4 264 GLN n 
4 265 VAL n 
4 266 TYR n 
4 267 LEU n 
4 268 HIS n 
4 269 GLU n 
4 270 SER n 
4 271 THR n 
4 272 GLN n 
4 273 ASP n 
4 274 GLU n 
4 275 LEU n 
4 276 ALA n 
4 277 ARG n 
4 278 LYS n 
4 279 CYS n 
4 280 GLU n 
4 281 GLN n 
4 282 VAL n 
4 283 LEU n 
4 284 ILE n 
4 285 GLU n 
4 286 LYS n 
4 287 HIS n 
4 288 LEU n 
4 289 GLU n 
4 290 ILE n 
4 291 PHE n 
4 292 HIS n 
4 293 THR n 
4 294 GLU n 
4 295 PHE n 
4 296 GLN n 
4 297 ASN n 
4 298 LEU n 
4 299 LEU n 
4 300 ASP n 
4 301 ALA n 
4 302 ASP n 
4 303 LYS n 
4 304 ASN n 
4 305 GLU n 
4 306 ASP n 
4 307 LEU n 
4 308 GLY n 
4 309 ARG n 
4 310 MET n 
4 311 TYR n 
4 312 ASN n 
4 313 LEU n 
4 314 VAL n 
4 315 SER n 
4 316 ARG n 
4 317 ILE n 
4 318 GLN n 
4 319 ASP n 
4 320 GLY n 
4 321 LEU n 
4 322 GLY n 
4 323 GLU n 
4 324 LEU n 
4 325 LYS n 
4 326 LYS n 
4 327 LEU n 
4 328 LEU n 
4 329 GLU n 
4 330 THR n 
4 331 HIS n 
4 332 ILE n 
4 333 HIS n 
4 334 ASN n 
4 335 GLN n 
4 336 GLY n 
4 337 LEU n 
4 338 ALA n 
4 339 ALA n 
4 340 ILE n 
4 341 GLU n 
4 342 LYS n 
4 343 CYS n 
4 344 GLY n 
4 345 GLU n 
4 346 ALA n 
4 347 ALA n 
4 348 LEU n 
4 349 ASN n 
4 350 ASP n 
4 351 PRO n 
4 352 LYS n 
4 353 MET n 
4 354 TYR n 
4 355 VAL n 
4 356 GLN n 
4 357 THR n 
4 358 VAL n 
4 359 LEU n 
4 360 ASP n 
4 361 VAL n 
4 362 HIS n 
4 363 LYS n 
4 364 LYS n 
4 365 TYR n 
4 366 ASN n 
4 367 ALA n 
4 368 LEU n 
4 369 VAL n 
4 370 MET n 
4 371 SER n 
4 372 ALA n 
4 373 PHE n 
4 374 ASN n 
4 375 ASN n 
4 376 ASP n 
4 377 ALA n 
4 378 GLY n 
4 379 PHE n 
4 380 VAL n 
4 381 ALA n 
4 382 ALA n 
4 383 LEU n 
4 384 ASP n 
4 385 LYS n 
4 386 ALA n 
4 387 CYS n 
4 388 GLY n 
4 389 ARG n 
4 390 PHE n 
4 391 ILE n 
4 392 ASN n 
4 393 ASN n 
4 394 ASN n 
4 395 ALA n 
4 396 VAL n 
4 397 THR n 
4 398 LYS n 
4 399 MET n 
4 400 ALA n 
4 401 GLN n 
4 402 SER n 
4 403 SER n 
4 404 SER n 
4 405 LYS n 
4 406 SER n 
4 407 PRO n 
4 408 GLU n 
4 409 LEU n 
4 410 LEU n 
4 411 ALA n 
4 412 ARG n 
4 413 TYR n 
4 414 CYS n 
4 415 ASP n 
4 416 SER n 
4 417 LEU n 
4 418 LEU n 
4 419 LYS n 
4 420 LYS n 
4 421 SER n 
4 422 SER n 
4 423 LYS n 
4 424 ASN n 
4 425 PRO n 
4 426 GLU n 
4 427 GLU n 
4 428 ALA n 
4 429 GLU n 
4 430 LEU n 
4 431 GLU n 
4 432 ASP n 
4 433 THR n 
4 434 LEU n 
4 435 ASN n 
4 436 GLN n 
4 437 VAL n 
4 438 MET n 
4 439 VAL n 
4 440 VAL n 
4 441 PHE n 
4 442 LYS n 
4 443 TYR n 
4 444 ILE n 
4 445 GLU n 
4 446 ASP n 
4 447 LYS n 
4 448 ASP n 
4 449 VAL n 
4 450 PHE n 
4 451 GLN n 
4 452 LYS n 
4 453 PHE n 
4 454 TYR n 
4 455 ALA n 
4 456 LYS n 
4 457 MET n 
4 458 LEU n 
4 459 ALA n 
4 460 LYS n 
4 461 ARG n 
4 462 LEU n 
4 463 VAL n 
4 464 HIS n 
4 465 GLN n 
4 466 ASN n 
4 467 SER n 
4 468 ALA n 
4 469 SER n 
4 470 ASP n 
4 471 ASP n 
4 472 ALA n 
4 473 GLU n 
4 474 ALA n 
4 475 SER n 
4 476 MET n 
4 477 ILE n 
4 478 SER n 
4 479 LYS n 
4 480 LEU n 
4 481 LYS n 
4 482 GLN n 
4 483 ALA n 
4 484 CYS n 
4 485 GLY n 
4 486 PHE n 
4 487 GLU n 
4 488 TYR n 
4 489 THR n 
4 490 SER n 
4 491 LYS n 
4 492 LEU n 
4 493 GLN n 
4 494 ARG n 
4 495 MET n 
4 496 PHE n 
4 497 GLN n 
4 498 ASP n 
4 499 ILE n 
4 500 GLY n 
4 501 VAL n 
4 502 SER n 
4 503 LYS n 
4 504 ASP n 
4 505 LEU n 
4 506 ASN n 
4 507 GLU n 
4 508 GLN n 
4 509 PHE n 
4 510 LYS n 
4 511 LYS n 
4 512 HIS n 
4 513 LEU n 
4 514 THR n 
4 515 ASN n 
4 516 SER n 
4 517 GLU n 
4 518 PRO n 
4 519 LEU n 
4 520 ASP n 
4 521 LEU n 
4 522 ASP n 
4 523 PHE n 
4 524 SER n 
4 525 ILE n 
4 526 GLN n 
4 527 VAL n 
4 528 LEU n 
4 529 SER n 
4 530 SER n 
4 531 GLY n 
4 532 SER n 
4 533 TRP n 
4 534 PRO n 
4 535 PHE n 
4 536 GLN n 
4 537 GLN n 
4 538 SER n 
4 539 CYS n 
4 540 THR n 
4 541 PHE n 
4 542 ALA n 
4 543 LEU n 
4 544 PRO n 
4 545 SER n 
4 546 GLU n 
4 547 LEU n 
4 548 GLU n 
4 549 ARG n 
4 550 SER n 
4 551 TYR n 
4 552 GLN n 
4 553 ARG n 
4 554 PHE n 
4 555 THR n 
4 556 ALA n 
4 557 PHE n 
4 558 TYR n 
4 559 ALA n 
4 560 SER n 
4 561 ARG n 
4 562 HIS n 
4 563 SER n 
4 564 GLY n 
4 565 ARG n 
4 566 LYS n 
4 567 LEU n 
4 568 THR n 
4 569 TRP n 
4 570 LEU n 
4 571 TYR n 
4 572 GLN n 
4 573 LEU n 
4 574 SER n 
4 575 LYS n 
4 576 GLY n 
4 577 GLU n 
4 578 LEU n 
4 579 VAL n 
4 580 THR n 
4 581 ASN n 
4 582 CYS n 
4 583 PHE n 
4 584 LYS n 
4 585 ASN n 
4 586 ARG n 
4 587 TYR n 
4 588 THR n 
4 589 LEU n 
4 590 GLN n 
4 591 ALA n 
4 592 SER n 
4 593 THR n 
4 594 PHE n 
4 595 GLN n 
4 596 MET n 
4 597 ALA n 
4 598 ILE n 
4 599 LEU n 
4 600 LEU n 
4 601 GLN n 
4 602 TYR n 
4 603 ASN n 
4 604 THR n 
4 605 GLU n 
4 606 ASP n 
4 607 ALA n 
4 608 TYR n 
4 609 THR n 
4 610 VAL n 
4 611 GLN n 
4 612 GLN n 
4 613 LEU n 
4 614 THR n 
4 615 ASP n 
4 616 SER n 
4 617 THR n 
4 618 GLN n 
4 619 ILE n 
4 620 LYS n 
4 621 MET n 
4 622 ASP n 
4 623 ILE n 
4 624 LEU n 
4 625 ALA n 
4 626 GLN n 
4 627 VAL n 
4 628 LEU n 
4 629 GLN n 
4 630 ILE n 
4 631 LEU n 
4 632 LEU n 
4 633 LYS n 
4 634 SER n 
4 635 LYS n 
4 636 LEU n 
4 637 LEU n 
4 638 VAL n 
4 639 LEU n 
4 640 GLU n 
4 641 ASP n 
4 642 GLU n 
4 643 ASN n 
4 644 ALA n 
4 645 ASN n 
4 646 VAL n 
4 647 ASP n 
4 648 GLU n 
4 649 VAL n 
4 650 GLU n 
4 651 LEU n 
4 652 LYS n 
4 653 PRO n 
4 654 ASP n 
4 655 THR n 
4 656 LEU n 
4 657 ILE n 
4 658 LYS n 
4 659 LEU n 
4 660 TYR n 
4 661 LEU n 
4 662 GLY n 
4 663 TYR n 
4 664 LYS n 
4 665 ASN n 
4 666 LYS n 
4 667 LYS n 
4 668 LEU n 
4 669 ARG n 
4 670 VAL n 
4 671 ASN n 
4 672 ILE n 
4 673 ASN n 
4 674 VAL n 
4 675 PRO n 
4 676 MET n 
4 677 LYS n 
4 678 THR n 
4 679 GLU n 
4 680 GLN n 
4 681 LYS n 
4 682 GLN n 
4 683 GLU n 
4 684 GLN n 
4 685 GLU n 
4 686 THR n 
4 687 THR n 
4 688 HIS n 
4 689 LYS n 
4 690 ASN n 
4 691 ILE n 
4 692 GLU n 
4 693 GLU n 
4 694 ASP n 
4 695 ARG n 
4 696 LYS n 
4 697 LEU n 
4 698 LEU n 
4 699 ILE n 
4 700 GLN n 
4 701 ALA n 
4 702 ALA n 
4 703 ILE n 
4 704 VAL n 
4 705 ARG n 
4 706 ILE n 
4 707 MET n 
4 708 LYS n 
4 709 MET n 
4 710 ARG n 
4 711 LYS n 
4 712 VAL n 
4 713 LEU n 
4 714 LYS n 
4 715 HIS n 
4 716 GLN n 
4 717 GLN n 
4 718 LEU n 
4 719 LEU n 
4 720 GLY n 
4 721 GLU n 
4 722 VAL n 
4 723 LEU n 
4 724 THR n 
4 725 GLN n 
4 726 LEU n 
4 727 SER n 
4 728 SER n 
4 729 ARG n 
4 730 PHE n 
4 731 LYS n 
4 732 PRO n 
4 733 ARG n 
4 734 VAL n 
4 735 PRO n 
4 736 VAL n 
4 737 ILE n 
4 738 LYS n 
4 739 LYS n 
4 740 CYS n 
4 741 ILE n 
4 742 ASP n 
4 743 ILE n 
4 744 LEU n 
4 745 ILE n 
4 746 GLU n 
4 747 LYS n 
4 748 GLU n 
4 749 TYR n 
4 750 LEU n 
4 751 GLU n 
4 752 ARG n 
4 753 VAL n 
4 754 ASP n 
4 755 GLY n 
4 756 GLU n 
4 757 LYS n 
4 758 ASP n 
4 759 THR n 
4 760 TYR n 
4 761 SER n 
4 762 TYR n 
4 763 LEU n 
4 764 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 403 human ? FBXO22 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'cabbage looper' 
'Trichoplusia ni'       7111   ? ? ? ? ? ? ? ? 'High Five' ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 122 human ? BACH1  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ?                
'Escherichia coli BL21' 511693 ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 160 human ? SKP1   ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'cabbage looper' 
'Trichoplusia ni'       7111   ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 764 human ? CUL1   ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ?                
'Escherichia coli BL21' 511693 ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   C . n 
A 1 2   GLU 2   2   ?   ?   ?   C . n 
A 1 3   PRO 3   3   ?   ?   ?   C . n 
A 1 4   VAL 4   4   ?   ?   ?   C . n 
A 1 5   GLY 5   5   ?   ?   ?   C . n 
A 1 6   CYS 6   6   ?   ?   ?   C . n 
A 1 7   CYS 7   7   ?   ?   ?   C . n 
A 1 8   GLY 8   8   ?   ?   ?   C . n 
A 1 9   GLU 9   9   ?   ?   ?   C . n 
A 1 10  CYS 10  10  ?   ?   ?   C . n 
A 1 11  ARG 11  11  ?   ?   ?   C . n 
A 1 12  GLY 12  12  ?   ?   ?   C . n 
A 1 13  SER 13  13  ?   ?   ?   C . n 
A 1 14  SER 14  14  ?   ?   ?   C . n 
A 1 15  VAL 15  15  ?   ?   ?   C . n 
A 1 16  ASP 16  16  16  ASP ASP C . n 
A 1 17  PRO 17  17  17  PRO PRO C . n 
A 1 18  ARG 18  18  18  ARG ARG C . n 
A 1 19  SER 19  19  19  SER SER C . n 
A 1 20  THR 20  20  20  THR THR C . n 
A 1 21  PHE 21  21  21  PHE PHE C . n 
A 1 22  VAL 22  22  22  VAL VAL C . n 
A 1 23  LEU 23  23  23  LEU LEU C . n 
A 1 24  SER 24  24  24  SER SER C . n 
A 1 25  ASN 25  25  25  ASN ASN C . n 
A 1 26  LEU 26  26  26  LEU LEU C . n 
A 1 27  ALA 27  27  27  ALA ALA C . n 
A 1 28  GLU 28  28  28  GLU GLU C . n 
A 1 29  VAL 29  29  29  VAL VAL C . n 
A 1 30  VAL 30  30  30  VAL VAL C . n 
A 1 31  GLU 31  31  31  GLU GLU C . n 
A 1 32  ARG 32  32  32  ARG ARG C . n 
A 1 33  VAL 33  33  33  VAL VAL C . n 
A 1 34  LEU 34  34  34  LEU LEU C . n 
A 1 35  THR 35  35  35  THR THR C . n 
A 1 36  PHE 36  36  36  PHE PHE C . n 
A 1 37  LEU 37  37  37  LEU LEU C . n 
A 1 38  PRO 38  38  38  PRO PRO C . n 
A 1 39  ALA 39  39  39  ALA ALA C . n 
A 1 40  LYS 40  40  40  LYS LYS C . n 
A 1 41  ALA 41  41  41  ALA ALA C . n 
A 1 42  LEU 42  42  42  LEU LEU C . n 
A 1 43  LEU 43  43  43  LEU LEU C . n 
A 1 44  ARG 44  44  44  ARG ARG C . n 
A 1 45  VAL 45  45  45  VAL VAL C . n 
A 1 46  ALA 46  46  46  ALA ALA C . n 
A 1 47  CYS 47  47  47  CYS CYS C . n 
A 1 48  VAL 48  48  48  VAL VAL C . n 
A 1 49  CYS 49  49  49  CYS CYS C . n 
A 1 50  ARG 50  50  50  ARG ARG C . n 
A 1 51  LEU 51  51  51  LEU LEU C . n 
A 1 52  TRP 52  52  52  TRP TRP C . n 
A 1 53  ARG 53  53  53  ARG ARG C . n 
A 1 54  GLU 54  54  54  GLU GLU C . n 
A 1 55  CYS 55  55  55  CYS CYS C . n 
A 1 56  VAL 56  56  56  VAL VAL C . n 
A 1 57  ARG 57  57  57  ARG ARG C . n 
A 1 58  ARG 58  58  58  ARG ARG C . n 
A 1 59  VAL 59  59  59  VAL VAL C . n 
A 1 60  LEU 60  60  60  LEU LEU C . n 
A 1 61  ARG 61  61  61  ARG ARG C . n 
A 1 62  THR 62  62  62  THR THR C . n 
A 1 63  HIS 63  63  63  HIS HIS C . n 
A 1 64  ARG 64  64  64  ARG ARG C . n 
A 1 65  SER 65  65  65  SER SER C . n 
A 1 66  VAL 66  66  66  VAL VAL C . n 
A 1 67  THR 67  67  67  THR THR C . n 
A 1 68  TRP 68  68  68  TRP TRP C . n 
A 1 69  ILE 69  69  69  ILE ILE C . n 
A 1 70  SER 70  70  70  SER SER C . n 
A 1 71  ALA 71  71  71  ALA ALA C . n 
A 1 72  GLY 72  72  72  GLY GLY C . n 
A 1 73  LEU 73  73  73  LEU LEU C . n 
A 1 74  ALA 74  74  74  ALA ALA C . n 
A 1 75  GLU 75  75  75  GLU GLU C . n 
A 1 76  ALA 76  76  76  ALA ALA C . n 
A 1 77  GLY 77  77  77  GLY GLY C . n 
A 1 78  HIS 78  78  78  HIS HIS C . n 
A 1 79  LEU 79  79  79  LEU LEU C . n 
A 1 80  GLU 80  80  80  GLU GLU C . n 
A 1 81  GLY 81  81  81  GLY GLY C . n 
A 1 82  HIS 82  82  82  HIS HIS C . n 
A 1 83  CYS 83  83  83  CYS CYS C . n 
A 1 84  LEU 84  84  84  LEU LEU C . n 
A 1 85  VAL 85  85  85  VAL VAL C . n 
A 1 86  ARG 86  86  86  ARG ARG C . n 
A 1 87  VAL 87  87  87  VAL VAL C . n 
A 1 88  VAL 88  88  88  VAL VAL C . n 
A 1 89  ALA 89  89  89  ALA ALA C . n 
A 1 90  GLU 90  90  90  GLU GLU C . n 
A 1 91  GLU 91  91  91  GLU GLU C . n 
A 1 92  LEU 92  92  92  LEU LEU C . n 
A 1 93  GLU 93  93  93  GLU GLU C . n 
A 1 94  ASN 94  94  94  ASN ASN C . n 
A 1 95  VAL 95  95  95  VAL VAL C . n 
A 1 96  ARG 96  96  96  ARG ARG C . n 
A 1 97  ILE 97  97  97  ILE ILE C . n 
A 1 98  LEU 98  98  98  LEU LEU C . n 
A 1 99  PRO 99  99  99  PRO PRO C . n 
A 1 100 HIS 100 100 100 HIS HIS C . n 
A 1 101 THR 101 101 101 THR THR C . n 
A 1 102 VAL 102 102 102 VAL VAL C . n 
A 1 103 LEU 103 103 103 LEU LEU C . n 
A 1 104 TYR 104 104 104 TYR TYR C . n 
A 1 105 MET 105 105 105 MET MET C . n 
A 1 106 ALA 106 106 106 ALA ALA C . n 
A 1 107 ASP 107 107 107 ASP ASP C . n 
A 1 108 SER 108 108 108 SER SER C . n 
A 1 109 GLU 109 109 109 GLU GLU C . n 
A 1 110 THR 110 110 110 THR THR C . n 
A 1 111 PHE 111 111 111 PHE PHE C . n 
A 1 112 ILE 112 112 112 ILE ILE C . n 
A 1 113 SER 113 113 113 SER SER C . n 
A 1 114 LEU 114 114 114 LEU LEU C . n 
A 1 115 GLU 115 115 115 GLU GLU C . n 
A 1 116 GLU 116 116 116 GLU GLU C . n 
A 1 117 CYS 117 117 ?   ?   ?   C . n 
A 1 118 ARG 118 118 ?   ?   ?   C . n 
A 1 119 GLY 119 119 ?   ?   ?   C . n 
A 1 120 HIS 120 120 ?   ?   ?   C . n 
A 1 121 LYS 121 121 ?   ?   ?   C . n 
A 1 122 ARG 122 122 ?   ?   ?   C . n 
A 1 123 ALA 123 123 ?   ?   ?   C . n 
A 1 124 ARG 124 124 ?   ?   ?   C . n 
A 1 125 LYS 125 125 ?   ?   ?   C . n 
A 1 126 ARG 126 126 ?   ?   ?   C . n 
A 1 127 THR 127 127 127 THR THR C . n 
A 1 128 SER 128 128 128 SER SER C . n 
A 1 129 MET 129 129 129 MET MET C . n 
A 1 130 GLU 130 130 130 GLU GLU C . n 
A 1 131 THR 131 131 131 THR THR C . n 
A 1 132 ALA 132 132 132 ALA ALA C . n 
A 1 133 LEU 133 133 133 LEU LEU C . n 
A 1 134 ALA 134 134 134 ALA ALA C . n 
A 1 135 LEU 135 135 135 LEU LEU C . n 
A 1 136 GLU 136 136 136 GLU GLU C . n 
A 1 137 LYS 137 137 137 LYS LYS C . n 
A 1 138 LEU 138 138 138 LEU LEU C . n 
A 1 139 PHE 139 139 139 PHE PHE C . n 
A 1 140 PRO 140 140 140 PRO PRO C . n 
A 1 141 LYS 141 141 141 LYS LYS C . n 
A 1 142 GLN 142 142 142 GLN GLN C . n 
A 1 143 CYS 143 143 143 CYS CYS C . n 
A 1 144 GLN 144 144 144 GLN GLN C . n 
A 1 145 VAL 145 145 145 VAL VAL C . n 
A 1 146 LEU 146 146 146 LEU LEU C . n 
A 1 147 GLY 147 147 147 GLY GLY C . n 
A 1 148 ILE 148 148 148 ILE ILE C . n 
A 1 149 VAL 149 149 149 VAL VAL C . n 
A 1 150 THR 150 150 150 THR THR C . n 
A 1 151 PRO 151 151 151 PRO PRO C . n 
A 1 152 GLY 152 152 152 GLY GLY C . n 
A 1 153 ILE 153 153 153 ILE ILE C . n 
A 1 154 VAL 154 154 154 VAL VAL C . n 
A 1 155 VAL 155 155 155 VAL VAL C . n 
A 1 156 THR 156 156 156 THR THR C . n 
A 1 157 PRO 157 157 157 PRO PRO C . n 
A 1 158 MET 158 158 158 MET MET C . n 
A 1 159 GLY 159 159 159 GLY GLY C . n 
A 1 160 SER 160 160 160 SER SER C . n 
A 1 161 GLY 161 161 161 GLY GLY C . n 
A 1 162 SER 162 162 162 SER SER C . n 
A 1 163 ASN 163 163 163 ASN ASN C . n 
A 1 164 ARG 164 164 164 ARG ARG C . n 
A 1 165 PRO 165 165 165 PRO PRO C . n 
A 1 166 GLN 166 166 166 GLN GLN C . n 
A 1 167 GLU 167 167 167 GLU GLU C . n 
A 1 168 ILE 168 168 168 ILE ILE C . n 
A 1 169 GLU 169 169 169 GLU GLU C . n 
A 1 170 ILE 170 170 170 ILE ILE C . n 
A 1 171 GLY 171 171 171 GLY GLY C . n 
A 1 172 GLU 172 172 172 GLU GLU C . n 
A 1 173 SER 173 173 173 SER SER C . n 
A 1 174 GLY 174 174 174 GLY GLY C . n 
A 1 175 PHE 175 175 175 PHE PHE C . n 
A 1 176 ALA 176 176 176 ALA ALA C . n 
A 1 177 LEU 177 177 177 LEU LEU C . n 
A 1 178 LEU 178 178 178 LEU LEU C . n 
A 1 179 PHE 179 179 179 PHE PHE C . n 
A 1 180 PRO 180 180 180 PRO PRO C . n 
A 1 181 GLN 181 181 181 GLN GLN C . n 
A 1 182 ILE 182 182 182 ILE ILE C . n 
A 1 183 GLU 183 183 183 GLU GLU C . n 
A 1 184 GLY 184 184 184 GLY GLY C . n 
A 1 185 ILE 185 185 185 ILE ILE C . n 
A 1 186 LYS 186 186 186 LYS LYS C . n 
A 1 187 ILE 187 187 187 ILE ILE C . n 
A 1 188 GLN 188 188 188 GLN GLN C . n 
A 1 189 PRO 189 189 189 PRO PRO C . n 
A 1 190 PHE 190 190 190 PHE PHE C . n 
A 1 191 HIS 191 191 191 HIS HIS C . n 
A 1 192 PHE 192 192 192 PHE PHE C . n 
A 1 193 ILE 193 193 193 ILE ILE C . n 
A 1 194 LYS 194 194 194 LYS LYS C . n 
A 1 195 ASP 195 195 195 ASP ASP C . n 
A 1 196 PRO 196 196 196 PRO PRO C . n 
A 1 197 LYS 197 197 197 LYS LYS C . n 
A 1 198 ASN 198 198 198 ASN ASN C . n 
A 1 199 LEU 199 199 199 LEU LEU C . n 
A 1 200 THR 200 200 200 THR THR C . n 
A 1 201 LEU 201 201 201 LEU LEU C . n 
A 1 202 GLU 202 202 202 GLU GLU C . n 
A 1 203 ARG 203 203 203 ARG ARG C . n 
A 1 204 HIS 204 204 204 HIS HIS C . n 
A 1 205 GLN 205 205 205 GLN GLN C . n 
A 1 206 LEU 206 206 206 LEU LEU C . n 
A 1 207 THR 207 207 207 THR THR C . n 
A 1 208 GLU 208 208 208 GLU GLU C . n 
A 1 209 VAL 209 209 209 VAL VAL C . n 
A 1 210 GLY 210 210 210 GLY GLY C . n 
A 1 211 LEU 211 211 211 LEU LEU C . n 
A 1 212 LEU 212 212 212 LEU LEU C . n 
A 1 213 ASP 213 213 213 ASP ASP C . n 
A 1 214 ASN 214 214 214 ASN ASN C . n 
A 1 215 PRO 215 215 215 PRO PRO C . n 
A 1 216 GLU 216 216 216 GLU GLU C . n 
A 1 217 LEU 217 217 217 LEU LEU C . n 
A 1 218 ARG 218 218 218 ARG ARG C . n 
A 1 219 VAL 219 219 219 VAL VAL C . n 
A 1 220 VAL 220 220 220 VAL VAL C . n 
A 1 221 LEU 221 221 221 LEU LEU C . n 
A 1 222 VAL 222 222 222 VAL VAL C . n 
A 1 223 PHE 223 223 223 PHE PHE C . n 
A 1 224 GLY 224 224 224 GLY GLY C . n 
A 1 225 TYR 225 225 225 TYR TYR C . n 
A 1 226 ASN 226 226 226 ASN ASN C . n 
A 1 227 CYS 227 227 227 CYS CYS C . n 
A 1 228 CYS 228 228 228 CYS CYS C . n 
A 1 229 LYS 229 229 229 LYS LYS C . n 
A 1 230 VAL 230 230 230 VAL VAL C . n 
A 1 231 GLY 231 231 231 GLY GLY C . n 
A 1 232 ALA 232 232 232 ALA ALA C . n 
A 1 233 SER 233 233 233 SER SER C . n 
A 1 234 ASN 234 234 234 ASN ASN C . n 
A 1 235 TYR 235 235 235 TYR TYR C . n 
A 1 236 LEU 236 236 236 LEU LEU C . n 
A 1 237 GLN 237 237 237 GLN GLN C . n 
A 1 238 GLN 238 238 238 GLN GLN C . n 
A 1 239 VAL 239 239 239 VAL VAL C . n 
A 1 240 VAL 240 240 240 VAL VAL C . n 
A 1 241 SER 241 241 241 SER SER C . n 
A 1 242 THR 242 242 242 THR THR C . n 
A 1 243 PHE 243 243 243 PHE PHE C . n 
A 1 244 SER 244 244 244 SER SER C . n 
A 1 245 ASP 245 245 245 ASP ASP C . n 
A 1 246 MET 246 246 246 MET MET C . n 
A 1 247 ASN 247 247 247 ASN ASN C . n 
A 1 248 ILE 248 248 248 ILE ILE C . n 
A 1 249 ILE 249 249 249 ILE ILE C . n 
A 1 250 LEU 250 250 250 LEU LEU C . n 
A 1 251 ALA 251 251 251 ALA ALA C . n 
A 1 252 GLY 252 252 252 GLY GLY C . n 
A 1 253 GLY 253 253 253 GLY GLY C . n 
A 1 254 GLN 254 254 254 GLN GLN C . n 
A 1 255 VAL 255 255 255 VAL VAL C . n 
A 1 256 ASP 256 256 256 ASP ASP C . n 
A 1 257 ASN 257 257 257 ASN ASN C . n 
A 1 258 LEU 258 258 258 LEU LEU C . n 
A 1 259 SER 259 259 259 SER SER C . n 
A 1 260 SER 260 260 260 SER SER C . n 
A 1 261 LEU 261 261 261 LEU LEU C . n 
A 1 262 THR 262 262 262 THR THR C . n 
A 1 263 SER 263 263 263 SER SER C . n 
A 1 264 GLU 264 264 264 GLU GLU C . n 
A 1 265 LYS 265 265 265 LYS LYS C . n 
A 1 266 ASN 266 266 266 ASN ASN C . n 
A 1 267 PRO 267 267 267 PRO PRO C . n 
A 1 268 LEU 268 268 268 LEU LEU C . n 
A 1 269 ASP 269 269 269 ASP ASP C . n 
A 1 270 ILE 270 270 270 ILE ILE C . n 
A 1 271 ASP 271 271 271 ASP ASP C . n 
A 1 272 ALA 272 272 272 ALA ALA C . n 
A 1 273 SER 273 273 273 SER SER C . n 
A 1 274 GLY 274 274 274 GLY GLY C . n 
A 1 275 VAL 275 275 275 VAL VAL C . n 
A 1 276 VAL 276 276 276 VAL VAL C . n 
A 1 277 GLY 277 277 277 GLY GLY C . n 
A 1 278 LEU 278 278 278 LEU LEU C . n 
A 1 279 SER 279 279 279 SER SER C . n 
A 1 280 PHE 280 280 280 PHE PHE C . n 
A 1 281 SER 281 281 281 SER SER C . n 
A 1 282 GLY 282 282 282 GLY GLY C . n 
A 1 283 HIS 283 283 283 HIS HIS C . n 
A 1 284 ARG 284 284 284 ARG ARG C . n 
A 1 285 ILE 285 285 285 ILE ILE C . n 
A 1 286 GLN 286 286 286 GLN GLN C . n 
A 1 287 SER 287 287 287 SER SER C . n 
A 1 288 ALA 288 288 288 ALA ALA C . n 
A 1 289 THR 289 289 289 THR THR C . n 
A 1 290 VAL 290 290 290 VAL VAL C . n 
A 1 291 LEU 291 291 291 LEU LEU C . n 
A 1 292 LEU 292 292 292 LEU LEU C . n 
A 1 293 ASN 293 293 293 ASN ASN C . n 
A 1 294 GLU 294 294 294 GLU GLU C . n 
A 1 295 ASP 295 295 295 ASP ASP C . n 
A 1 296 VAL 296 296 296 VAL VAL C . n 
A 1 297 SER 297 297 297 SER SER C . n 
A 1 298 ASP 298 298 298 ASP ASP C . n 
A 1 299 GLU 299 299 299 GLU GLU C . n 
A 1 300 LYS 300 300 300 LYS LYS C . n 
A 1 301 THR 301 301 301 THR THR C . n 
A 1 302 ALA 302 302 302 ALA ALA C . n 
A 1 303 GLU 303 303 303 GLU GLU C . n 
A 1 304 ALA 304 304 304 ALA ALA C . n 
A 1 305 ALA 305 305 305 ALA ALA C . n 
A 1 306 MET 306 306 306 MET MET C . n 
A 1 307 GLN 307 307 307 GLN GLN C . n 
A 1 308 ARG 308 308 308 ARG ARG C . n 
A 1 309 LEU 309 309 309 LEU LEU C . n 
A 1 310 LYS 310 310 310 LYS LYS C . n 
A 1 311 ALA 311 311 311 ALA ALA C . n 
A 1 312 ALA 312 312 312 ALA ALA C . n 
A 1 313 ASN 313 313 313 ASN ASN C . n 
A 1 314 ILE 314 314 314 ILE ILE C . n 
A 1 315 PRO 315 315 315 PRO PRO C . n 
A 1 316 GLU 316 316 316 GLU GLU C . n 
A 1 317 HIS 317 317 317 HIS HIS C . n 
A 1 318 ASN 318 318 318 ASN ASN C . n 
A 1 319 THR 319 319 319 THR THR C . n 
A 1 320 ILE 320 320 320 ILE ILE C . n 
A 1 321 GLY 321 321 321 GLY GLY C . n 
A 1 322 PHE 322 322 322 PHE PHE C . n 
A 1 323 MET 323 323 323 MET MET C . n 
A 1 324 PHE 324 324 324 PHE PHE C . n 
A 1 325 ALA 325 325 325 ALA ALA C . n 
A 1 326 CYS 326 326 326 CYS CYS C . n 
A 1 327 VAL 327 327 327 VAL VAL C . n 
A 1 328 GLY 328 328 328 GLY GLY C . n 
A 1 329 ARG 329 329 329 ARG ARG C . n 
A 1 330 GLY 330 330 330 GLY GLY C . n 
A 1 331 PHE 331 331 331 PHE PHE C . n 
A 1 332 GLN 332 332 332 GLN GLN C . n 
A 1 333 TYR 333 333 333 TYR TYR C . n 
A 1 334 TYR 334 334 334 TYR TYR C . n 
A 1 335 ARG 335 335 335 ARG ARG C . n 
A 1 336 ALA 336 336 336 ALA ALA C . n 
A 1 337 LYS 337 337 337 LYS LYS C . n 
A 1 338 GLY 338 338 338 GLY GLY C . n 
A 1 339 ASN 339 339 339 ASN ASN C . n 
A 1 340 VAL 340 340 340 VAL VAL C . n 
A 1 341 GLU 341 341 341 GLU GLU C . n 
A 1 342 ALA 342 342 342 ALA ALA C . n 
A 1 343 ASP 343 343 343 ASP ASP C . n 
A 1 344 ALA 344 344 344 ALA ALA C . n 
A 1 345 PHE 345 345 345 PHE PHE C . n 
A 1 346 ARG 346 346 346 ARG ARG C . n 
A 1 347 LYS 347 347 347 LYS LYS C . n 
A 1 348 PHE 348 348 348 PHE PHE C . n 
A 1 349 PHE 349 349 349 PHE PHE C . n 
A 1 350 PRO 350 350 350 PRO PRO C . n 
A 1 351 SER 351 351 351 SER SER C . n 
A 1 352 VAL 352 352 352 VAL VAL C . n 
A 1 353 PRO 353 353 353 PRO PRO C . n 
A 1 354 LEU 354 354 354 LEU LEU C . n 
A 1 355 PHE 355 355 355 PHE PHE C . n 
A 1 356 GLY 356 356 356 GLY GLY C . n 
A 1 357 PHE 357 357 357 PHE PHE C . n 
A 1 358 PHE 358 358 358 PHE PHE C . n 
A 1 359 GLY 359 359 359 GLY GLY C . n 
A 1 360 ASN 360 360 360 ASN ASN C . n 
A 1 361 GLY 361 361 361 GLY GLY C . n 
A 1 362 GLU 362 362 362 GLU GLU C . n 
A 1 363 ILE 363 363 363 ILE ILE C . n 
A 1 364 GLY 364 364 364 GLY GLY C . n 
A 1 365 CYS 365 365 365 CYS CYS C . n 
A 1 366 ASP 366 366 366 ASP ASP C . n 
A 1 367 ARG 367 367 367 ARG ARG C . n 
A 1 368 ILE 368 368 368 ILE ILE C . n 
A 1 369 VAL 369 369 369 VAL VAL C . n 
A 1 370 THR 370 370 370 THR THR C . n 
A 1 371 GLY 371 371 371 GLY GLY C . n 
A 1 372 ASN 372 372 372 ASN ASN C . n 
A 1 373 PHE 373 373 373 PHE PHE C . n 
A 1 374 ILE 374 374 374 ILE ILE C . n 
A 1 375 LEU 375 375 375 LEU LEU C . n 
A 1 376 ARG 376 376 376 ARG ARG C . n 
A 1 377 LYS 377 377 377 LYS LYS C . n 
A 1 378 CYS 378 378 378 CYS CYS C . n 
A 1 379 ASN 379 379 379 ASN ASN C . n 
A 1 380 GLU 380 380 380 GLU GLU C . n 
A 1 381 VAL 381 381 381 VAL VAL C . n 
A 1 382 LYS 382 382 382 LYS LYS C . n 
A 1 383 ASP 383 383 383 ASP ASP C . n 
A 1 384 ASP 384 384 384 ASP ASP C . n 
A 1 385 ASP 385 385 385 ASP ASP C . n 
A 1 386 LEU 386 386 386 LEU LEU C . n 
A 1 387 PHE 387 387 387 PHE PHE C . n 
A 1 388 HIS 388 388 388 HIS HIS C . n 
A 1 389 SER 389 389 389 SER SER C . n 
A 1 390 TYR 390 390 390 TYR TYR C . n 
A 1 391 THR 391 391 391 THR THR C . n 
A 1 392 THR 392 392 392 THR THR C . n 
A 1 393 ILE 393 393 393 ILE ILE C . n 
A 1 394 MET 394 394 394 MET MET C . n 
A 1 395 ALA 395 395 395 ALA ALA C . n 
A 1 396 LEU 396 396 396 LEU LEU C . n 
A 1 397 ILE 397 397 397 ILE ILE C . n 
A 1 398 HIS 398 398 398 HIS HIS C . n 
A 1 399 LEU 399 399 399 LEU LEU C . n 
A 1 400 GLY 400 400 400 GLY GLY C . n 
A 1 401 SER 401 401 401 SER SER C . n 
A 1 402 SER 402 402 ?   ?   ?   C . n 
A 1 403 LYS 403 403 ?   ?   ?   C . n 
B 2 1   SER 1   7   7   SER SER D . n 
B 2 2   VAL 2   8   8   VAL VAL D . n 
B 2 3   PHE 3   9   9   PHE PHE D . n 
B 2 4   ALA 4   10  10  ALA ALA D . n 
B 2 5   TYR 5   11  11  TYR TYR D . n 
B 2 6   GLU 6   12  12  GLU GLU D . n 
B 2 7   SER 7   13  13  SER SER D . n 
B 2 8   SER 8   14  14  SER SER D . n 
B 2 9   VAL 9   15  15  VAL VAL D . n 
B 2 10  HIS 10  16  16  HIS HIS D . n 
B 2 11  SER 11  17  17  SER SER D . n 
B 2 12  THR 12  18  18  THR THR D . n 
B 2 13  ASN 13  19  19  ASN ASN D . n 
B 2 14  VAL 14  20  20  VAL VAL D . n 
B 2 15  LEU 15  21  21  LEU LEU D . n 
B 2 16  LEU 16  22  22  LEU LEU D . n 
B 2 17  SER 17  23  23  SER SER D . n 
B 2 18  LEU 18  24  24  LEU LEU D . n 
B 2 19  ASN 19  25  25  ASN ASN D . n 
B 2 20  ASP 20  26  26  ASP ASP D . n 
B 2 21  GLN 21  27  27  GLN GLN D . n 
B 2 22  ARG 22  28  28  ARG ARG D . n 
B 2 23  LYS 23  29  29  LYS LYS D . n 
B 2 24  LYS 24  30  30  LYS LYS D . n 
B 2 25  ASP 25  31  31  ASP ASP D . n 
B 2 26  VAL 26  32  32  VAL VAL D . n 
B 2 27  LEU 27  33  33  LEU LEU D . n 
B 2 28  CYS 28  34  34  CYS CYS D . n 
B 2 29  ASP 29  35  35  ASP ASP D . n 
B 2 30  VAL 30  36  36  VAL VAL D . n 
B 2 31  THR 31  37  37  THR THR D . n 
B 2 32  ILE 32  38  38  ILE ILE D . n 
B 2 33  PHE 33  39  39  PHE PHE D . n 
B 2 34  VAL 34  40  40  VAL VAL D . n 
B 2 35  GLU 35  41  41  GLU GLU D . n 
B 2 36  GLY 36  42  42  GLY GLY D . n 
B 2 37  GLN 37  43  43  GLN GLN D . n 
B 2 38  ARG 38  44  44  ARG ARG D . n 
B 2 39  PHE 39  45  45  PHE PHE D . n 
B 2 40  ARG 40  46  46  ARG ARG D . n 
B 2 41  ALA 41  47  47  ALA ALA D . n 
B 2 42  HIS 42  48  48  HIS HIS D . n 
B 2 43  ARG 43  49  49  ARG ARG D . n 
B 2 44  SER 44  50  50  SER SER D . n 
B 2 45  VAL 45  51  51  VAL VAL D . n 
B 2 46  LEU 46  52  52  LEU LEU D . n 
B 2 47  ALA 47  53  53  ALA ALA D . n 
B 2 48  ALA 48  54  54  ALA ALA D . n 
B 2 49  CYS 49  55  55  CYS CYS D . n 
B 2 50  SER 50  56  56  SER SER D . n 
B 2 51  SER 51  57  57  SER SER D . n 
B 2 52  TYR 52  58  58  TYR TYR D . n 
B 2 53  PHE 53  59  59  PHE PHE D . n 
B 2 54  HIS 54  60  60  HIS HIS D . n 
B 2 55  SER 55  61  61  SER SER D . n 
B 2 56  ARG 56  62  62  ARG ARG D . n 
B 2 57  ILE 57  63  63  ILE ILE D . n 
B 2 58  VAL 58  64  64  VAL VAL D . n 
B 2 59  GLY 59  65  65  GLY GLY D . n 
B 2 60  GLN 60  66  66  GLN GLN D . n 
B 2 61  ALA 61  67  67  ALA ALA D . n 
B 2 62  ASP 62  68  68  ASP ASP D . n 
B 2 63  GLY 63  69  69  GLY GLY D . n 
B 2 64  GLU 64  70  70  GLU GLU D . n 
B 2 65  LEU 65  71  71  LEU LEU D . n 
B 2 66  ASN 66  72  72  ASN ASN D . n 
B 2 67  ILE 67  73  73  ILE ILE D . n 
B 2 68  THR 68  74  74  THR THR D . n 
B 2 69  LEU 69  75  75  LEU LEU D . n 
B 2 70  PRO 70  76  76  PRO PRO D . n 
B 2 71  GLU 71  77  77  GLU GLU D . n 
B 2 72  GLU 72  78  78  GLU GLU D . n 
B 2 73  VAL 73  79  79  VAL VAL D . n 
B 2 74  THR 74  80  80  THR THR D . n 
B 2 75  VAL 75  81  81  VAL VAL D . n 
B 2 76  LYS 76  82  82  LYS LYS D . n 
B 2 77  GLY 77  83  83  GLY GLY D . n 
B 2 78  PHE 78  84  84  PHE PHE D . n 
B 2 79  GLU 79  85  85  GLU GLU D . n 
B 2 80  PRO 80  86  86  PRO PRO D . n 
B 2 81  LEU 81  87  87  LEU LEU D . n 
B 2 82  ILE 82  88  88  ILE ILE D . n 
B 2 83  GLN 83  89  89  GLN GLN D . n 
B 2 84  PHE 84  90  90  PHE PHE D . n 
B 2 85  ALA 85  91  91  ALA ALA D . n 
B 2 86  TYR 86  92  92  TYR TYR D . n 
B 2 87  THR 87  93  93  THR THR D . n 
B 2 88  ALA 88  94  94  ALA ALA D . n 
B 2 89  LYS 89  95  95  LYS LYS D . n 
B 2 90  LEU 90  96  96  LEU LEU D . n 
B 2 91  ILE 91  97  97  ILE ILE D . n 
B 2 92  LEU 92  98  98  LEU LEU D . n 
B 2 93  SER 93  99  99  SER SER D . n 
B 2 94  LYS 94  100 100 LYS LYS D . n 
B 2 95  GLU 95  101 101 GLU GLU D . n 
B 2 96  ASN 96  102 102 ASN ASN D . n 
B 2 97  VAL 97  103 103 VAL VAL D . n 
B 2 98  ASP 98  104 104 ASP ASP D . n 
B 2 99  GLU 99  105 105 GLU GLU D . n 
B 2 100 VAL 100 106 106 VAL VAL D . n 
B 2 101 CYS 101 107 107 CYS CYS D . n 
B 2 102 LYS 102 108 108 LYS LYS D . n 
B 2 103 CYS 103 109 109 CYS CYS D . n 
B 2 104 VAL 104 110 110 VAL VAL D . n 
B 2 105 GLU 105 111 111 GLU GLU D . n 
B 2 106 PHE 106 112 112 PHE PHE D . n 
B 2 107 LEU 107 113 113 LEU LEU D . n 
B 2 108 SER 108 114 114 SER SER D . n 
B 2 109 VAL 109 115 115 VAL VAL D . n 
B 2 110 HIS 110 116 116 HIS HIS D . n 
B 2 111 ASN 111 117 117 ASN ASN D . n 
B 2 112 ILE 112 118 118 ILE ILE D . n 
B 2 113 GLU 113 119 119 GLU GLU D . n 
B 2 114 GLU 114 120 120 GLU GLU D . n 
B 2 115 SER 115 121 121 SER SER D . n 
B 2 116 CYS 116 122 122 CYS CYS D . n 
B 2 117 PHE 117 123 123 PHE PHE D . n 
B 2 118 GLN 118 124 124 GLN GLN D . n 
B 2 119 PHE 119 125 125 PHE PHE D . n 
B 2 120 LEU 120 126 126 LEU LEU D . n 
B 2 121 LYS 121 127 127 LYS LYS D . n 
B 2 122 PHE 122 128 128 PHE PHE D . n 
C 2 1   SER 1   7   7   SER SER E . n 
C 2 2   VAL 2   8   8   VAL VAL E . n 
C 2 3   PHE 3   9   9   PHE PHE E . n 
C 2 4   ALA 4   10  10  ALA ALA E . n 
C 2 5   TYR 5   11  11  TYR TYR E . n 
C 2 6   GLU 6   12  12  GLU GLU E . n 
C 2 7   SER 7   13  13  SER SER E . n 
C 2 8   SER 8   14  14  SER SER E . n 
C 2 9   VAL 9   15  15  VAL VAL E . n 
C 2 10  HIS 10  16  16  HIS HIS E . n 
C 2 11  SER 11  17  17  SER SER E . n 
C 2 12  THR 12  18  18  THR THR E . n 
C 2 13  ASN 13  19  19  ASN ASN E . n 
C 2 14  VAL 14  20  20  VAL VAL E . n 
C 2 15  LEU 15  21  21  LEU LEU E . n 
C 2 16  LEU 16  22  22  LEU LEU E . n 
C 2 17  SER 17  23  23  SER SER E . n 
C 2 18  LEU 18  24  24  LEU LEU E . n 
C 2 19  ASN 19  25  25  ASN ASN E . n 
C 2 20  ASP 20  26  26  ASP ASP E . n 
C 2 21  GLN 21  27  27  GLN GLN E . n 
C 2 22  ARG 22  28  28  ARG ARG E . n 
C 2 23  LYS 23  29  29  LYS LYS E . n 
C 2 24  LYS 24  30  30  LYS LYS E . n 
C 2 25  ASP 25  31  31  ASP ASP E . n 
C 2 26  VAL 26  32  32  VAL VAL E . n 
C 2 27  LEU 27  33  33  LEU LEU E . n 
C 2 28  CYS 28  34  34  CYS CYS E . n 
C 2 29  ASP 29  35  35  ASP ASP E . n 
C 2 30  VAL 30  36  36  VAL VAL E . n 
C 2 31  THR 31  37  37  THR THR E . n 
C 2 32  ILE 32  38  38  ILE ILE E . n 
C 2 33  PHE 33  39  39  PHE PHE E . n 
C 2 34  VAL 34  40  40  VAL VAL E . n 
C 2 35  GLU 35  41  41  GLU GLU E . n 
C 2 36  GLY 36  42  42  GLY GLY E . n 
C 2 37  GLN 37  43  43  GLN GLN E . n 
C 2 38  ARG 38  44  44  ARG ARG E . n 
C 2 39  PHE 39  45  45  PHE PHE E . n 
C 2 40  ARG 40  46  46  ARG ARG E . n 
C 2 41  ALA 41  47  47  ALA ALA E . n 
C 2 42  HIS 42  48  48  HIS HIS E . n 
C 2 43  ARG 43  49  49  ARG ARG E . n 
C 2 44  SER 44  50  50  SER SER E . n 
C 2 45  VAL 45  51  51  VAL VAL E . n 
C 2 46  LEU 46  52  52  LEU LEU E . n 
C 2 47  ALA 47  53  53  ALA ALA E . n 
C 2 48  ALA 48  54  54  ALA ALA E . n 
C 2 49  CYS 49  55  55  CYS CYS E . n 
C 2 50  SER 50  56  56  SER SER E . n 
C 2 51  SER 51  57  57  SER SER E . n 
C 2 52  TYR 52  58  58  TYR TYR E . n 
C 2 53  PHE 53  59  59  PHE PHE E . n 
C 2 54  HIS 54  60  60  HIS HIS E . n 
C 2 55  SER 55  61  61  SER SER E . n 
C 2 56  ARG 56  62  62  ARG ARG E . n 
C 2 57  ILE 57  63  63  ILE ILE E . n 
C 2 58  VAL 58  64  64  VAL VAL E . n 
C 2 59  GLY 59  65  65  GLY GLY E . n 
C 2 60  GLN 60  66  66  GLN GLN E . n 
C 2 61  ALA 61  67  67  ALA ALA E . n 
C 2 62  ASP 62  68  68  ASP ASP E . n 
C 2 63  GLY 63  69  69  GLY GLY E . n 
C 2 64  GLU 64  70  70  GLU GLU E . n 
C 2 65  LEU 65  71  71  LEU LEU E . n 
C 2 66  ASN 66  72  72  ASN ASN E . n 
C 2 67  ILE 67  73  73  ILE ILE E . n 
C 2 68  THR 68  74  74  THR THR E . n 
C 2 69  LEU 69  75  75  LEU LEU E . n 
C 2 70  PRO 70  76  76  PRO PRO E . n 
C 2 71  GLU 71  77  77  GLU GLU E . n 
C 2 72  GLU 72  78  78  GLU GLU E . n 
C 2 73  VAL 73  79  79  VAL VAL E . n 
C 2 74  THR 74  80  80  THR THR E . n 
C 2 75  VAL 75  81  81  VAL VAL E . n 
C 2 76  LYS 76  82  82  LYS LYS E . n 
C 2 77  GLY 77  83  83  GLY GLY E . n 
C 2 78  PHE 78  84  84  PHE PHE E . n 
C 2 79  GLU 79  85  85  GLU GLU E . n 
C 2 80  PRO 80  86  86  PRO PRO E . n 
C 2 81  LEU 81  87  87  LEU LEU E . n 
C 2 82  ILE 82  88  88  ILE ILE E . n 
C 2 83  GLN 83  89  89  GLN GLN E . n 
C 2 84  PHE 84  90  90  PHE PHE E . n 
C 2 85  ALA 85  91  91  ALA ALA E . n 
C 2 86  TYR 86  92  92  TYR TYR E . n 
C 2 87  THR 87  93  93  THR THR E . n 
C 2 88  ALA 88  94  94  ALA ALA E . n 
C 2 89  LYS 89  95  95  LYS LYS E . n 
C 2 90  LEU 90  96  96  LEU LEU E . n 
C 2 91  ILE 91  97  97  ILE ILE E . n 
C 2 92  LEU 92  98  98  LEU LEU E . n 
C 2 93  SER 93  99  99  SER SER E . n 
C 2 94  LYS 94  100 100 LYS LYS E . n 
C 2 95  GLU 95  101 101 GLU GLU E . n 
C 2 96  ASN 96  102 102 ASN ASN E . n 
C 2 97  VAL 97  103 103 VAL VAL E . n 
C 2 98  ASP 98  104 104 ASP ASP E . n 
C 2 99  GLU 99  105 105 GLU GLU E . n 
C 2 100 VAL 100 106 106 VAL VAL E . n 
C 2 101 CYS 101 107 107 CYS CYS E . n 
C 2 102 LYS 102 108 108 LYS LYS E . n 
C 2 103 CYS 103 109 109 CYS CYS E . n 
C 2 104 VAL 104 110 110 VAL VAL E . n 
C 2 105 GLU 105 111 111 GLU GLU E . n 
C 2 106 PHE 106 112 112 PHE PHE E . n 
C 2 107 LEU 107 113 113 LEU LEU E . n 
C 2 108 SER 108 114 114 SER SER E . n 
C 2 109 VAL 109 115 115 VAL VAL E . n 
C 2 110 HIS 110 116 116 HIS HIS E . n 
C 2 111 ASN 111 117 117 ASN ASN E . n 
C 2 112 ILE 112 118 118 ILE ILE E . n 
C 2 113 GLU 113 119 119 GLU GLU E . n 
C 2 114 GLU 114 120 120 GLU GLU E . n 
C 2 115 SER 115 121 121 SER SER E . n 
C 2 116 CYS 116 122 122 CYS CYS E . n 
C 2 117 PHE 117 123 123 PHE PHE E . n 
C 2 118 GLN 118 124 124 GLN GLN E . n 
C 2 119 PHE 119 125 125 PHE PHE E . n 
C 2 120 LEU 120 126 126 LEU LEU E . n 
C 2 121 LYS 121 127 127 LYS LYS E . n 
C 2 122 PHE 122 128 ?   ?   ?   E . n 
D 3 1   MET 1   1   ?   ?   ?   B . n 
D 3 2   PRO 2   2   2   PRO PRO B . n 
D 3 3   SER 3   3   3   SER SER B . n 
D 3 4   ILE 4   4   4   ILE ILE B . n 
D 3 5   LYS 5   5   5   LYS LYS B . n 
D 3 6   LEU 6   6   6   LEU LEU B . n 
D 3 7   GLN 7   7   7   GLN GLN B . n 
D 3 8   SER 8   8   8   SER SER B . n 
D 3 9   SER 9   9   9   SER SER B . n 
D 3 10  ASP 10  10  10  ASP ASP B . n 
D 3 11  GLY 11  11  11  GLY GLY B . n 
D 3 12  GLU 12  12  12  GLU GLU B . n 
D 3 13  ILE 13  13  13  ILE ILE B . n 
D 3 14  PHE 14  14  14  PHE PHE B . n 
D 3 15  GLU 15  15  15  GLU GLU B . n 
D 3 16  VAL 16  16  16  VAL VAL B . n 
D 3 17  ASP 17  17  17  ASP ASP B . n 
D 3 18  VAL 18  18  18  VAL VAL B . n 
D 3 19  GLU 19  19  19  GLU GLU B . n 
D 3 20  ILE 20  20  20  ILE ILE B . n 
D 3 21  ALA 21  21  21  ALA ALA B . n 
D 3 22  LYS 22  22  22  LYS LYS B . n 
D 3 23  GLN 23  23  23  GLN GLN B . n 
D 3 24  SER 24  24  24  SER SER B . n 
D 3 25  VAL 25  25  25  VAL VAL B . n 
D 3 26  THR 26  26  26  THR THR B . n 
D 3 27  ILE 27  27  27  ILE ILE B . n 
D 3 28  LYS 28  28  28  LYS LYS B . n 
D 3 29  THR 29  29  29  THR THR B . n 
D 3 30  MET 30  30  30  MET MET B . n 
D 3 31  LEU 31  31  31  LEU LEU B . n 
D 3 32  GLU 32  32  32  GLU GLU B . n 
D 3 33  ASP 33  33  33  ASP ASP B . n 
D 3 34  LEU 34  34  34  LEU LEU B . n 
D 3 35  GLY 35  35  35  GLY GLY B . n 
D 3 36  MET 36  36  36  MET MET B . n 
D 3 37  ASP 37  37  37  ASP ASP B . n 
D 3 38  ASP 38  38  38  ASP ASP B . n 
D 3 39  GLU 39  39  39  GLU GLU B . n 
D 3 40  GLY 40  40  40  GLY GLY B . n 
D 3 41  ASP 41  41  41  ASP ASP B . n 
D 3 42  ASP 42  42  42  ASP ASP B . n 
D 3 43  ASP 43  43  43  ASP ASP B . n 
D 3 44  PRO 44  44  44  PRO PRO B . n 
D 3 45  VAL 45  45  45  VAL VAL B . n 
D 3 46  PRO 46  46  46  PRO PRO B . n 
D 3 47  LEU 47  47  47  LEU LEU B . n 
D 3 48  PRO 48  48  48  PRO PRO B . n 
D 3 49  ASN 49  49  49  ASN ASN B . n 
D 3 50  VAL 50  50  50  VAL VAL B . n 
D 3 51  ASN 51  51  51  ASN ASN B . n 
D 3 52  ALA 52  52  52  ALA ALA B . n 
D 3 53  ALA 53  53  53  ALA ALA B . n 
D 3 54  ILE 54  54  54  ILE ILE B . n 
D 3 55  LEU 55  55  55  LEU LEU B . n 
D 3 56  LYS 56  56  56  LYS LYS B . n 
D 3 57  LYS 57  57  57  LYS LYS B . n 
D 3 58  VAL 58  58  58  VAL VAL B . n 
D 3 59  ILE 59  59  59  ILE ILE B . n 
D 3 60  GLN 60  60  60  GLN GLN B . n 
D 3 61  TRP 61  61  61  TRP TRP B . n 
D 3 62  CYS 62  62  62  CYS CYS B . n 
D 3 63  THR 63  63  63  THR THR B . n 
D 3 64  HIS 64  64  64  HIS HIS B . n 
D 3 65  HIS 65  65  65  HIS HIS B . n 
D 3 66  LYS 66  66  66  LYS LYS B . n 
D 3 67  ASP 67  67  67  ASP ASP B . n 
D 3 68  ASP 68  68  68  ASP ASP B . n 
D 3 69  PRO 69  69  69  PRO PRO B . n 
D 3 70  PRO 70  70  70  PRO PRO B . n 
D 3 71  PRO 71  71  71  PRO PRO B . n 
D 3 72  PRO 72  72  ?   ?   ?   B . n 
D 3 73  GLU 73  73  ?   ?   ?   B . n 
D 3 74  ASP 74  74  ?   ?   ?   B . n 
D 3 75  ASP 75  75  ?   ?   ?   B . n 
D 3 76  GLU 76  76  ?   ?   ?   B . n 
D 3 77  ASN 77  77  77  ASN ASN B . n 
D 3 78  LYS 78  78  78  LYS LYS B . n 
D 3 79  GLU 79  79  79  GLU GLU B . n 
D 3 80  LYS 80  80  80  LYS LYS B . n 
D 3 81  ARG 81  81  81  ARG ARG B . n 
D 3 82  THR 82  82  82  THR THR B . n 
D 3 83  ASP 83  83  83  ASP ASP B . n 
D 3 84  ASP 84  84  84  ASP ASP B . n 
D 3 85  ILE 85  85  85  ILE ILE B . n 
D 3 86  PRO 86  86  86  PRO PRO B . n 
D 3 87  VAL 87  87  87  VAL VAL B . n 
D 3 88  TRP 88  88  88  TRP TRP B . n 
D 3 89  ASP 89  89  89  ASP ASP B . n 
D 3 90  GLN 90  90  90  GLN GLN B . n 
D 3 91  GLU 91  91  91  GLU GLU B . n 
D 3 92  PHE 92  92  92  PHE PHE B . n 
D 3 93  LEU 93  93  93  LEU LEU B . n 
D 3 94  LYS 94  94  94  LYS LYS B . n 
D 3 95  VAL 95  95  95  VAL VAL B . n 
D 3 96  ASP 96  96  96  ASP ASP B . n 
D 3 97  GLN 97  97  97  GLN GLN B . n 
D 3 98  GLY 98  98  98  GLY GLY B . n 
D 3 99  THR 99  99  99  THR THR B . n 
D 3 100 LEU 100 100 100 LEU LEU B . n 
D 3 101 PHE 101 101 101 PHE PHE B . n 
D 3 102 GLU 102 102 102 GLU GLU B . n 
D 3 103 LEU 103 103 103 LEU LEU B . n 
D 3 104 ILE 104 104 104 ILE ILE B . n 
D 3 105 LEU 105 105 105 LEU LEU B . n 
D 3 106 ALA 106 106 106 ALA ALA B . n 
D 3 107 ALA 107 107 107 ALA ALA B . n 
D 3 108 ASN 108 108 108 ASN ASN B . n 
D 3 109 TYR 109 109 109 TYR TYR B . n 
D 3 110 LEU 110 110 110 LEU LEU B . n 
D 3 111 ASP 111 111 111 ASP ASP B . n 
D 3 112 ILE 112 112 112 ILE ILE B . n 
D 3 113 LYS 113 113 113 LYS LYS B . n 
D 3 114 GLY 114 114 114 GLY GLY B . n 
D 3 115 LEU 115 115 115 LEU LEU B . n 
D 3 116 LEU 116 116 116 LEU LEU B . n 
D 3 117 ASP 117 117 117 ASP ASP B . n 
D 3 118 VAL 118 118 118 VAL VAL B . n 
D 3 119 THR 119 119 119 THR THR B . n 
D 3 120 CYS 120 120 120 CYS CYS B . n 
D 3 121 LYS 121 121 121 LYS LYS B . n 
D 3 122 THR 122 122 122 THR THR B . n 
D 3 123 VAL 123 123 123 VAL VAL B . n 
D 3 124 ALA 124 124 124 ALA ALA B . n 
D 3 125 ASN 125 125 125 ASN ASN B . n 
D 3 126 MET 126 126 126 MET MET B . n 
D 3 127 ILE 127 127 127 ILE ILE B . n 
D 3 128 LYS 128 128 128 LYS LYS B . n 
D 3 129 GLY 129 129 129 GLY GLY B . n 
D 3 130 LYS 130 130 130 LYS LYS B . n 
D 3 131 THR 131 131 131 THR THR B . n 
D 3 132 PRO 132 132 132 PRO PRO B . n 
D 3 133 GLU 133 133 133 GLU GLU B . n 
D 3 134 GLU 134 134 134 GLU GLU B . n 
D 3 135 ILE 135 135 135 ILE ILE B . n 
D 3 136 ARG 136 136 136 ARG ARG B . n 
D 3 137 LYS 137 137 137 LYS LYS B . n 
D 3 138 THR 138 138 138 THR THR B . n 
D 3 139 PHE 139 139 139 PHE PHE B . n 
D 3 140 ASN 140 140 140 ASN ASN B . n 
D 3 141 ILE 141 141 141 ILE ILE B . n 
D 3 142 LYS 142 142 142 LYS LYS B . n 
D 3 143 ASN 143 143 143 ASN ASN B . n 
D 3 144 ASP 144 144 144 ASP ASP B . n 
D 3 145 PHE 145 145 145 PHE PHE B . n 
D 3 146 THR 146 146 146 THR THR B . n 
D 3 147 GLU 147 147 147 GLU GLU B . n 
D 3 148 GLU 148 148 148 GLU GLU B . n 
D 3 149 GLU 149 149 149 GLU GLU B . n 
D 3 150 GLU 150 150 150 GLU GLU B . n 
D 3 151 ALA 151 151 151 ALA ALA B . n 
D 3 152 GLN 152 152 152 GLN GLN B . n 
D 3 153 VAL 153 153 153 VAL VAL B . n 
D 3 154 GLY 154 154 154 GLY GLY B . n 
D 3 155 SER 155 155 155 SER SER B . n 
D 3 156 THR 156 156 156 THR THR B . n 
D 3 157 GLN 157 157 157 GLN GLN B . n 
D 3 158 PHE 158 158 158 PHE PHE B . n 
D 3 159 CYS 159 159 159 CYS CYS B . n 
D 3 160 LEU 160 160 160 LEU LEU B . n 
E 4 1   LYS 1   13  13  LYS LYS A . n 
E 4 2   GLN 2   14  14  GLN GLN A . n 
E 4 3   ILE 3   15  15  ILE ILE A . n 
E 4 4   GLY 4   16  16  GLY GLY A . n 
E 4 5   LEU 5   17  17  LEU LEU A . n 
E 4 6   ASP 6   18  18  ASP ASP A . n 
E 4 7   GLN 7   19  19  GLN GLN A . n 
E 4 8   ILE 8   20  20  ILE ILE A . n 
E 4 9   TRP 9   21  21  TRP TRP A . n 
E 4 10  ASP 10  22  22  ASP ASP A . n 
E 4 11  ASP 11  23  23  ASP ASP A . n 
E 4 12  LEU 12  24  24  LEU LEU A . n 
E 4 13  ARG 13  25  25  ARG ARG A . n 
E 4 14  ALA 14  26  26  ALA ALA A . n 
E 4 15  GLY 15  27  27  GLY GLY A . n 
E 4 16  ILE 16  28  28  ILE ILE A . n 
E 4 17  GLN 17  29  29  GLN GLN A . n 
E 4 18  GLN 18  30  30  GLN GLN A . n 
E 4 19  VAL 19  31  31  VAL VAL A . n 
E 4 20  TYR 20  32  32  TYR TYR A . n 
E 4 21  THR 21  33  33  THR THR A . n 
E 4 22  ARG 22  34  34  ARG ARG A . n 
E 4 23  GLN 23  35  35  GLN GLN A . n 
E 4 24  SER 24  36  36  SER SER A . n 
E 4 25  MET 25  37  37  MET MET A . n 
E 4 26  ALA 26  38  38  ALA ALA A . n 
E 4 27  LYS 27  39  39  LYS LYS A . n 
E 4 28  SER 28  40  40  SER SER A . n 
E 4 29  ARG 29  41  41  ARG ARG A . n 
E 4 30  TYR 30  42  42  TYR TYR A . n 
E 4 31  MET 31  43  43  MET MET A . n 
E 4 32  GLU 32  44  44  GLU GLU A . n 
E 4 33  LEU 33  45  45  LEU LEU A . n 
E 4 34  TYR 34  46  46  TYR TYR A . n 
E 4 35  THR 35  47  47  THR THR A . n 
E 4 36  HIS 36  48  48  HIS HIS A . n 
E 4 37  VAL 37  49  49  VAL VAL A . n 
E 4 38  TYR 38  50  50  TYR TYR A . n 
E 4 39  ASN 39  51  51  ASN ASN A . n 
E 4 40  TYR 40  52  52  TYR TYR A . n 
E 4 41  CYS 41  53  53  CYS CYS A . n 
E 4 42  THR 42  54  54  THR THR A . n 
E 4 43  SER 43  55  55  SER SER A . n 
E 4 44  VAL 44  56  56  VAL VAL A . n 
E 4 45  HIS 45  57  57  HIS HIS A . n 
E 4 46  GLN 46  58  ?   ?   ?   A . n 
E 4 47  SER 47  59  ?   ?   ?   A . n 
E 4 48  ASN 48  60  ?   ?   ?   A . n 
E 4 49  GLN 49  61  ?   ?   ?   A . n 
E 4 50  ALA 50  62  ?   ?   ?   A . n 
E 4 51  ARG 51  63  ?   ?   ?   A . n 
E 4 52  GLY 52  64  ?   ?   ?   A . n 
E 4 53  ALA 53  65  ?   ?   ?   A . n 
E 4 54  GLY 54  66  ?   ?   ?   A . n 
E 4 55  VAL 55  67  ?   ?   ?   A . n 
E 4 56  PRO 56  68  ?   ?   ?   A . n 
E 4 57  PRO 57  69  ?   ?   ?   A . n 
E 4 58  SER 58  70  ?   ?   ?   A . n 
E 4 59  LYS 59  71  ?   ?   ?   A . n 
E 4 60  SER 60  72  ?   ?   ?   A . n 
E 4 61  LYS 61  73  ?   ?   ?   A . n 
E 4 62  LYS 62  74  ?   ?   ?   A . n 
E 4 63  GLY 63  75  ?   ?   ?   A . n 
E 4 64  GLN 64  76  ?   ?   ?   A . n 
E 4 65  THR 65  77  ?   ?   ?   A . n 
E 4 66  PRO 66  78  ?   ?   ?   A . n 
E 4 67  GLY 67  79  ?   ?   ?   A . n 
E 4 68  GLY 68  80  ?   ?   ?   A . n 
E 4 69  ALA 69  81  ?   ?   ?   A . n 
E 4 70  GLN 70  82  82  GLN GLN A . n 
E 4 71  PHE 71  83  83  PHE PHE A . n 
E 4 72  VAL 72  84  84  VAL VAL A . n 
E 4 73  GLY 73  85  85  GLY GLY A . n 
E 4 74  LEU 74  86  86  LEU LEU A . n 
E 4 75  GLU 75  87  87  GLU GLU A . n 
E 4 76  LEU 76  88  88  LEU LEU A . n 
E 4 77  TYR 77  89  89  TYR TYR A . n 
E 4 78  LYS 78  90  90  LYS LYS A . n 
E 4 79  ARG 79  91  91  ARG ARG A . n 
E 4 80  LEU 80  92  92  LEU LEU A . n 
E 4 81  LYS 81  93  93  LYS LYS A . n 
E 4 82  GLU 82  94  94  GLU GLU A . n 
E 4 83  PHE 83  95  95  PHE PHE A . n 
E 4 84  LEU 84  96  96  LEU LEU A . n 
E 4 85  LYS 85  97  97  LYS LYS A . n 
E 4 86  ASN 86  98  98  ASN ASN A . n 
E 4 87  TYR 87  99  99  TYR TYR A . n 
E 4 88  LEU 88  100 100 LEU LEU A . n 
E 4 89  THR 89  101 101 THR THR A . n 
E 4 90  ASN 90  102 102 ASN ASN A . n 
E 4 91  LEU 91  103 103 LEU LEU A . n 
E 4 92  LEU 92  104 104 LEU LEU A . n 
E 4 93  LYS 93  105 105 LYS LYS A . n 
E 4 94  ASP 94  106 106 ASP ASP A . n 
E 4 95  GLY 95  107 107 GLY GLY A . n 
E 4 96  GLU 96  108 108 GLU GLU A . n 
E 4 97  ASP 97  109 109 ASP ASP A . n 
E 4 98  LEU 98  110 110 LEU LEU A . n 
E 4 99  MET 99  111 111 MET MET A . n 
E 4 100 ASP 100 112 112 ASP ASP A . n 
E 4 101 GLU 101 113 113 GLU GLU A . n 
E 4 102 SER 102 114 114 SER SER A . n 
E 4 103 VAL 103 115 115 VAL VAL A . n 
E 4 104 LEU 104 116 116 LEU LEU A . n 
E 4 105 LYS 105 117 117 LYS LYS A . n 
E 4 106 PHE 106 118 118 PHE PHE A . n 
E 4 107 TYR 107 119 119 TYR TYR A . n 
E 4 108 THR 108 120 120 THR THR A . n 
E 4 109 GLN 109 121 121 GLN GLN A . n 
E 4 110 GLN 110 122 122 GLN GLN A . n 
E 4 111 TRP 111 123 123 TRP TRP A . n 
E 4 112 GLU 112 124 124 GLU GLU A . n 
E 4 113 ASP 113 125 125 ASP ASP A . n 
E 4 114 TYR 114 126 126 TYR TYR A . n 
E 4 115 ARG 115 127 127 ARG ARG A . n 
E 4 116 PHE 116 128 128 PHE PHE A . n 
E 4 117 SER 117 129 129 SER SER A . n 
E 4 118 SER 118 130 130 SER SER A . n 
E 4 119 LYS 119 131 131 LYS LYS A . n 
E 4 120 VAL 120 132 132 VAL VAL A . n 
E 4 121 LEU 121 133 133 LEU LEU A . n 
E 4 122 ASN 122 134 134 ASN ASN A . n 
E 4 123 GLY 123 135 135 GLY GLY A . n 
E 4 124 ILE 124 136 136 ILE ILE A . n 
E 4 125 CYS 125 137 137 CYS CYS A . n 
E 4 126 ALA 126 138 138 ALA ALA A . n 
E 4 127 TYR 127 139 139 TYR TYR A . n 
E 4 128 LEU 128 140 140 LEU LEU A . n 
E 4 129 ASN 129 141 141 ASN ASN A . n 
E 4 130 ARG 130 142 142 ARG ARG A . n 
E 4 131 HIS 131 143 143 HIS HIS A . n 
E 4 132 TRP 132 144 144 TRP TRP A . n 
E 4 133 VAL 133 145 145 VAL VAL A . n 
E 4 134 ARG 134 146 146 ARG ARG A . n 
E 4 135 ARG 135 147 147 ARG ARG A . n 
E 4 136 GLU 136 148 148 GLU GLY A . n 
E 4 137 CYS 137 149 149 CYS CYS A . n 
E 4 138 ASP 138 150 150 ASP ASP A . n 
E 4 139 GLU 139 151 151 GLU GLU A . n 
E 4 140 GLY 140 152 152 GLY ALA A . n 
E 4 141 ARG 141 153 153 ARG ARG A . n 
E 4 142 LYS 142 154 154 LYS LYS A . n 
E 4 143 GLY 143 155 155 GLY GLY A . n 
E 4 144 ILE 144 156 156 ILE ILE A . n 
E 4 145 TYR 145 157 157 TYR TYR A . n 
E 4 146 GLU 146 158 158 GLU GLU A . n 
E 4 147 ILE 147 159 159 ILE ILE A . n 
E 4 148 TYR 148 160 160 TYR TYR A . n 
E 4 149 SER 149 161 161 SER SER A . n 
E 4 150 LEU 150 162 162 LEU LEU A . n 
E 4 151 ALA 151 163 163 ALA ALA A . n 
E 4 152 LEU 152 164 164 LEU LEU A . n 
E 4 153 VAL 153 165 165 VAL VAL A . n 
E 4 154 THR 154 166 166 THR THR A . n 
E 4 155 TRP 155 167 167 TRP TRP A . n 
E 4 156 ARG 156 168 168 ARG ARG A . n 
E 4 157 ASP 157 169 169 ASP ASP A . n 
E 4 158 CYS 158 170 170 CYS CYS A . n 
E 4 159 LEU 159 171 171 LEU LEU A . n 
E 4 160 PHE 160 172 172 PHE PHE A . n 
E 4 161 ARG 161 173 173 ARG ARG A . n 
E 4 162 PRO 162 174 174 PRO PRO A . n 
E 4 163 LEU 163 175 175 LEU LEU A . n 
E 4 164 ASN 164 176 176 ASN ASN A . n 
E 4 165 LYS 165 177 177 LYS LYS A . n 
E 4 166 GLN 166 178 178 GLN GLN A . n 
E 4 167 VAL 167 179 179 VAL VAL A . n 
E 4 168 THR 168 180 180 THR THR A . n 
E 4 169 ASN 169 181 181 ASN ASN A . n 
E 4 170 ALA 170 182 182 ALA ALA A . n 
E 4 171 VAL 171 183 183 VAL VAL A . n 
E 4 172 LEU 172 184 184 LEU LEU A . n 
E 4 173 LYS 173 185 185 LYS LYS A . n 
E 4 174 LEU 174 186 186 LEU LEU A . n 
E 4 175 ILE 175 187 187 ILE ILE A . n 
E 4 176 GLU 176 188 188 GLU GLU A . n 
E 4 177 LYS 177 189 189 LYS LYS A . n 
E 4 178 GLU 178 190 190 GLU GLU A . n 
E 4 179 ARG 179 191 191 ARG ARG A . n 
E 4 180 ASN 180 192 192 ASN ASN A . n 
E 4 181 GLY 181 193 193 GLY GLY A . n 
E 4 182 GLU 182 194 194 GLU GLU A . n 
E 4 183 THR 183 195 195 THR THR A . n 
E 4 184 ILE 184 196 196 ILE ILE A . n 
E 4 185 ASN 185 197 197 ASN ASN A . n 
E 4 186 THR 186 198 198 THR THR A . n 
E 4 187 ARG 187 199 199 ARG ARG A . n 
E 4 188 LEU 188 200 200 LEU LEU A . n 
E 4 189 ILE 189 201 201 ILE ILE A . n 
E 4 190 SER 190 202 202 SER SER A . n 
E 4 191 GLY 191 203 203 GLY GLY A . n 
E 4 192 VAL 192 204 204 VAL VAL A . n 
E 4 193 VAL 193 205 205 VAL VAL A . n 
E 4 194 GLN 194 206 206 GLN GLN A . n 
E 4 195 SER 195 207 207 SER SER A . n 
E 4 196 TYR 196 208 208 TYR TYR A . n 
E 4 197 VAL 197 209 209 VAL VAL A . n 
E 4 198 GLU 198 210 210 GLU GLU A . n 
E 4 199 LEU 199 211 211 LEU LEU A . n 
E 4 200 GLY 200 212 212 GLY GLY A . n 
E 4 201 LEU 201 213 213 LEU LEU A . n 
E 4 202 ASN 202 214 214 ASN ASN A . n 
E 4 203 GLU 203 215 215 GLU GLU A . n 
E 4 204 ASP 204 216 216 ASP ASP A . n 
E 4 205 ASP 205 217 217 ASP ASP A . n 
E 4 206 ALA 206 218 218 ALA ALA A . n 
E 4 207 PHE 207 219 219 PHE PHE A . n 
E 4 208 ALA 208 220 220 ALA ALA A . n 
E 4 209 LYS 209 221 ?   ?   ?   A . n 
E 4 210 GLY 210 222 222 GLY GLY A . n 
E 4 211 PRO 211 223 223 PRO PRO A . n 
E 4 212 THR 212 224 224 THR THR A . n 
E 4 213 LEU 213 225 225 LEU LEU A . n 
E 4 214 THR 214 226 226 THR THR A . n 
E 4 215 VAL 215 227 227 VAL VAL A . n 
E 4 216 TYR 216 228 228 TYR TYR A . n 
E 4 217 LYS 217 229 229 LYS LYS A . n 
E 4 218 GLU 218 230 230 GLU GLU A . n 
E 4 219 SER 219 231 231 SER SER A . n 
E 4 220 PHE 220 232 232 PHE PHE A . n 
E 4 221 GLU 221 233 233 GLU GLU A . n 
E 4 222 SER 222 234 234 SER SER A . n 
E 4 223 GLN 223 235 235 GLN GLN A . n 
E 4 224 PHE 224 236 236 PHE PHE A . n 
E 4 225 LEU 225 237 237 LEU LEU A . n 
E 4 226 ALA 226 238 238 ALA ALA A . n 
E 4 227 ASP 227 239 239 ASP ASP A . n 
E 4 228 THR 228 240 240 THR THR A . n 
E 4 229 GLU 229 241 241 GLU GLU A . n 
E 4 230 ARG 230 242 242 ARG ARG A . n 
E 4 231 PHE 231 243 243 PHE PHE A . n 
E 4 232 TYR 232 244 244 TYR TYR A . n 
E 4 233 THR 233 245 245 THR THR A . n 
E 4 234 ARG 234 246 246 ARG ARG A . n 
E 4 235 GLU 235 247 247 GLU GLU A . n 
E 4 236 SER 236 248 248 SER SER A . n 
E 4 237 THR 237 249 249 THR THR A . n 
E 4 238 GLU 238 250 250 GLU GLU A . n 
E 4 239 PHE 239 251 251 PHE PHE A . n 
E 4 240 LEU 240 252 252 LEU LEU A . n 
E 4 241 GLN 241 253 253 GLN GLN A . n 
E 4 242 GLN 242 254 254 GLN GLN A . n 
E 4 243 ASN 243 255 255 ASN ASN A . n 
E 4 244 PRO 244 256 256 PRO PRO A . n 
E 4 245 VAL 245 257 257 VAL VAL A . n 
E 4 246 THR 246 258 258 THR THR A . n 
E 4 247 GLU 247 259 259 GLU GLU A . n 
E 4 248 TYR 248 260 260 TYR TYR A . n 
E 4 249 MET 249 261 261 MET MET A . n 
E 4 250 LYS 250 262 262 LYS LYS A . n 
E 4 251 LYS 251 263 263 LYS LYS A . n 
E 4 252 ALA 252 264 264 ALA ALA A . n 
E 4 253 GLU 253 265 265 GLU GLU A . n 
E 4 254 ALA 254 266 266 ALA ALA A . n 
E 4 255 ARG 255 267 267 ARG ARG A . n 
E 4 256 LEU 256 268 268 LEU LEU A . n 
E 4 257 LEU 257 269 269 LEU LEU A . n 
E 4 258 GLU 258 270 270 GLU GLU A . n 
E 4 259 GLU 259 271 271 GLU GLU A . n 
E 4 260 GLN 260 272 272 GLN GLN A . n 
E 4 261 ARG 261 273 273 ARG ARG A . n 
E 4 262 ARG 262 274 274 ARG ARG A . n 
E 4 263 VAL 263 275 275 VAL VAL A . n 
E 4 264 GLN 264 276 276 GLN GLN A . n 
E 4 265 VAL 265 277 277 VAL VAL A . n 
E 4 266 TYR 266 278 278 TYR TYR A . n 
E 4 267 LEU 267 279 279 LEU LEU A . n 
E 4 268 HIS 268 280 280 HIS HIS A . n 
E 4 269 GLU 269 281 281 GLU GLU A . n 
E 4 270 SER 270 282 282 SER SER A . n 
E 4 271 THR 271 283 283 THR THR A . n 
E 4 272 GLN 272 284 284 GLN GLN A . n 
E 4 273 ASP 273 285 285 ASP ASP A . n 
E 4 274 GLU 274 286 286 GLU GLU A . n 
E 4 275 LEU 275 287 287 LEU LEU A . n 
E 4 276 ALA 276 288 288 ALA ALA A . n 
E 4 277 ARG 277 289 289 ARG ARG A . n 
E 4 278 LYS 278 290 290 LYS LYS A . n 
E 4 279 CYS 279 291 291 CYS CYS A . n 
E 4 280 GLU 280 292 292 GLU GLU A . n 
E 4 281 GLN 281 293 293 GLN GLN A . n 
E 4 282 VAL 282 294 294 VAL VAL A . n 
E 4 283 LEU 283 295 295 LEU LEU A . n 
E 4 284 ILE 284 296 296 ILE ILE A . n 
E 4 285 GLU 285 297 297 GLU GLU A . n 
E 4 286 LYS 286 298 298 LYS LYS A . n 
E 4 287 HIS 287 299 299 HIS HIS A . n 
E 4 288 LEU 288 300 300 LEU LEU A . n 
E 4 289 GLU 289 301 301 GLU GLU A . n 
E 4 290 ILE 290 302 302 ILE ILE A . n 
E 4 291 PHE 291 303 303 PHE PHE A . n 
E 4 292 HIS 292 304 304 HIS HIS A . n 
E 4 293 THR 293 305 305 THR THR A . n 
E 4 294 GLU 294 306 306 GLU GLU A . n 
E 4 295 PHE 295 307 307 PHE PHE A . n 
E 4 296 GLN 296 308 308 GLN GLN A . n 
E 4 297 ASN 297 309 309 ASN ASN A . n 
E 4 298 LEU 298 310 310 LEU LEU A . n 
E 4 299 LEU 299 311 311 LEU LEU A . n 
E 4 300 ASP 300 312 312 ASP ASP A . n 
E 4 301 ALA 301 313 313 ALA ALA A . n 
E 4 302 ASP 302 314 314 ASP ASP A . n 
E 4 303 LYS 303 315 315 LYS LYS A . n 
E 4 304 ASN 304 316 316 ASN ASN A . n 
E 4 305 GLU 305 317 317 GLU GLU A . n 
E 4 306 ASP 306 318 318 ASP ASP A . n 
E 4 307 LEU 307 319 319 LEU LEU A . n 
E 4 308 GLY 308 320 320 GLY GLY A . n 
E 4 309 ARG 309 321 321 ARG ARG A . n 
E 4 310 MET 310 322 322 MET MET A . n 
E 4 311 TYR 311 323 323 TYR TYR A . n 
E 4 312 ASN 312 324 324 ASN ASN A . n 
E 4 313 LEU 313 325 325 LEU LEU A . n 
E 4 314 VAL 314 326 326 VAL VAL A . n 
E 4 315 SER 315 327 327 SER SER A . n 
E 4 316 ARG 316 328 328 ARG ARG A . n 
E 4 317 ILE 317 329 329 ILE ILE A . n 
E 4 318 GLN 318 330 330 GLN GLN A . n 
E 4 319 ASP 319 331 331 ASP ASP A . n 
E 4 320 GLY 320 332 332 GLY GLY A . n 
E 4 321 LEU 321 333 333 LEU LEU A . n 
E 4 322 GLY 322 334 334 GLY GLY A . n 
E 4 323 GLU 323 335 335 GLU GLU A . n 
E 4 324 LEU 324 336 336 LEU LEU A . n 
E 4 325 LYS 325 337 337 LYS LYS A . n 
E 4 326 LYS 326 338 338 LYS LYS A . n 
E 4 327 LEU 327 339 339 LEU LEU A . n 
E 4 328 LEU 328 340 340 LEU LEU A . n 
E 4 329 GLU 329 341 341 GLU GLU A . n 
E 4 330 THR 330 342 342 THR THR A . n 
E 4 331 HIS 331 343 343 HIS HIS A . n 
E 4 332 ILE 332 344 344 ILE ILE A . n 
E 4 333 HIS 333 345 345 HIS HIS A . n 
E 4 334 ASN 334 346 346 ASN ASN A . n 
E 4 335 GLN 335 347 347 GLN GLN A . n 
E 4 336 GLY 336 348 348 GLY GLY A . n 
E 4 337 LEU 337 349 349 LEU LEU A . n 
E 4 338 ALA 338 350 350 ALA ALA A . n 
E 4 339 ALA 339 351 351 ALA ALA A . n 
E 4 340 ILE 340 352 352 ILE ILE A . n 
E 4 341 GLU 341 353 353 GLU GLU A . n 
E 4 342 LYS 342 354 354 LYS LYS A . n 
E 4 343 CYS 343 355 355 CYS CYS A . n 
E 4 344 GLY 344 356 356 GLY GLY A . n 
E 4 345 GLU 345 357 357 GLU GLU A . n 
E 4 346 ALA 346 358 358 ALA ALA A . n 
E 4 347 ALA 347 359 359 ALA ALA A . n 
E 4 348 LEU 348 360 360 LEU LEU A . n 
E 4 349 ASN 349 361 361 ASN ASN A . n 
E 4 350 ASP 350 362 362 ASP ASP A . n 
E 4 351 PRO 351 363 363 PRO PRO A . n 
E 4 352 LYS 352 364 364 LYS LYS A . n 
E 4 353 MET 353 365 365 MET MET A . n 
E 4 354 TYR 354 366 366 TYR TYR A . n 
E 4 355 VAL 355 367 367 VAL VAL A . n 
E 4 356 GLN 356 368 368 GLN GLN A . n 
E 4 357 THR 357 369 369 THR THR A . n 
E 4 358 VAL 358 370 370 VAL VAL A . n 
E 4 359 LEU 359 371 371 LEU LEU A . n 
E 4 360 ASP 360 372 372 ASP ASP A . n 
E 4 361 VAL 361 373 373 VAL VAL A . n 
E 4 362 HIS 362 374 374 HIS HIS A . n 
E 4 363 LYS 363 375 375 LYS LYS A . n 
E 4 364 LYS 364 376 376 LYS LYS A . n 
E 4 365 TYR 365 377 377 TYR TYR A . n 
E 4 366 ASN 366 378 378 ASN ASN A . n 
E 4 367 ALA 367 379 379 ALA ALA A . n 
E 4 368 LEU 368 380 380 LEU LEU A . n 
E 4 369 VAL 369 381 381 VAL VAL A . n 
E 4 370 MET 370 382 382 MET MET A . n 
E 4 371 SER 371 383 383 SER SER A . n 
E 4 372 ALA 372 384 384 ALA ALA A . n 
E 4 373 PHE 373 385 385 PHE PHE A . n 
E 4 374 ASN 374 386 386 ASN ASN A . n 
E 4 375 ASN 375 387 387 ASN ASN A . n 
E 4 376 ASP 376 388 388 ASP ASP A . n 
E 4 377 ALA 377 389 389 ALA ALA A . n 
E 4 378 GLY 378 390 390 GLY GLY A . n 
E 4 379 PHE 379 391 391 PHE PHE A . n 
E 4 380 VAL 380 392 392 VAL VAL A . n 
E 4 381 ALA 381 393 393 ALA ALA A . n 
E 4 382 ALA 382 394 394 ALA ALA A . n 
E 4 383 LEU 383 395 395 LEU LEU A . n 
E 4 384 ASP 384 396 396 ASP ASP A . n 
E 4 385 LYS 385 397 397 LYS LYS A . n 
E 4 386 ALA 386 398 398 ALA ALA A . n 
E 4 387 CYS 387 399 399 CYS CYS A . n 
E 4 388 GLY 388 400 400 GLY GLY A . n 
E 4 389 ARG 389 401 401 ARG ARG A . n 
E 4 390 PHE 390 402 402 PHE PHE A . n 
E 4 391 ILE 391 403 403 ILE ILE A . n 
E 4 392 ASN 392 404 404 ASN ASN A . n 
E 4 393 ASN 393 405 405 ASN ASN A . n 
E 4 394 ASN 394 406 406 ASN ASN A . n 
E 4 395 ALA 395 407 407 ALA ALA A . n 
E 4 396 VAL 396 408 408 VAL VAL A . n 
E 4 397 THR 397 409 409 THR THR A . n 
E 4 398 LYS 398 410 410 LYS LYS A . n 
E 4 399 MET 399 411 411 MET MET A . n 
E 4 400 ALA 400 412 412 ALA ALA A . n 
E 4 401 GLN 401 413 413 GLN GLN A . n 
E 4 402 SER 402 414 414 SER SER A . n 
E 4 403 SER 403 415 415 SER SER A . n 
E 4 404 SER 404 416 416 SER SER A . n 
E 4 405 LYS 405 417 417 LYS LYS A . n 
E 4 406 SER 406 418 418 SER SER A . n 
E 4 407 PRO 407 419 419 PRO PRO A . n 
E 4 408 GLU 408 420 420 GLU GLU A . n 
E 4 409 LEU 409 421 421 LEU LEU A . n 
E 4 410 LEU 410 422 422 LEU LEU A . n 
E 4 411 ALA 411 423 423 ALA ALA A . n 
E 4 412 ARG 412 424 424 ARG ARG A . n 
E 4 413 TYR 413 425 425 TYR TYR A . n 
E 4 414 CYS 414 426 426 CYS CYS A . n 
E 4 415 ASP 415 427 427 ASP ASP A . n 
E 4 416 SER 416 428 428 SER SER A . n 
E 4 417 LEU 417 429 429 LEU LEU A . n 
E 4 418 LEU 418 430 430 LEU LEU A . n 
E 4 419 LYS 419 431 431 LYS LYS A . n 
E 4 420 LYS 420 432 432 LYS LYS A . n 
E 4 421 SER 421 433 433 SER SER A . n 
E 4 422 SER 422 434 434 SER SER A . n 
E 4 423 LYS 423 435 435 LYS LYS A . n 
E 4 424 ASN 424 436 436 ASN ASN A . n 
E 4 425 PRO 425 437 437 PRO PRO A . n 
E 4 426 GLU 426 438 438 GLU GLU A . n 
E 4 427 GLU 427 439 439 GLU GLU A . n 
E 4 428 ALA 428 440 440 ALA ALA A . n 
E 4 429 GLU 429 441 441 GLU GLU A . n 
E 4 430 LEU 430 442 442 LEU LEU A . n 
E 4 431 GLU 431 443 443 GLU GLU A . n 
E 4 432 ASP 432 444 444 ASP ASP A . n 
E 4 433 THR 433 445 445 THR THR A . n 
E 4 434 LEU 434 446 446 LEU LEU A . n 
E 4 435 ASN 435 447 447 ASN ASN A . n 
E 4 436 GLN 436 448 448 GLN GLN A . n 
E 4 437 VAL 437 449 449 VAL VAL A . n 
E 4 438 MET 438 450 450 MET MET A . n 
E 4 439 VAL 439 451 451 VAL VAL A . n 
E 4 440 VAL 440 452 452 VAL VAL A . n 
E 4 441 PHE 441 453 453 PHE PHE A . n 
E 4 442 LYS 442 454 454 LYS LYS A . n 
E 4 443 TYR 443 455 455 TYR TYR A . n 
E 4 444 ILE 444 456 456 ILE ILE A . n 
E 4 445 GLU 445 457 457 GLU GLU A . n 
E 4 446 ASP 446 458 458 ASP ASP A . n 
E 4 447 LYS 447 459 459 LYS LYS A . n 
E 4 448 ASP 448 460 460 ASP ASP A . n 
E 4 449 VAL 449 461 461 VAL VAL A . n 
E 4 450 PHE 450 462 462 PHE PHE A . n 
E 4 451 GLN 451 463 463 GLN GLN A . n 
E 4 452 LYS 452 464 464 LYS LYS A . n 
E 4 453 PHE 453 465 465 PHE PHE A . n 
E 4 454 TYR 454 466 466 TYR TYR A . n 
E 4 455 ALA 455 467 467 ALA ALA A . n 
E 4 456 LYS 456 468 468 LYS LYS A . n 
E 4 457 MET 457 469 469 MET MET A . n 
E 4 458 LEU 458 470 470 LEU LEU A . n 
E 4 459 ALA 459 471 471 ALA ALA A . n 
E 4 460 LYS 460 472 472 LYS LYS A . n 
E 4 461 ARG 461 473 473 ARG ARG A . n 
E 4 462 LEU 462 474 474 LEU LEU A . n 
E 4 463 VAL 463 475 475 VAL VAL A . n 
E 4 464 HIS 464 476 476 HIS HIS A . n 
E 4 465 GLN 465 477 477 GLN GLN A . n 
E 4 466 ASN 466 478 478 ASN ASN A . n 
E 4 467 SER 467 479 479 SER SER A . n 
E 4 468 ALA 468 480 480 ALA ALA A . n 
E 4 469 SER 469 481 481 SER SER A . n 
E 4 470 ASP 470 482 482 ASP ASP A . n 
E 4 471 ASP 471 483 483 ASP ASP A . n 
E 4 472 ALA 472 484 484 ALA ALA A . n 
E 4 473 GLU 473 485 485 GLU GLU A . n 
E 4 474 ALA 474 486 486 ALA ALA A . n 
E 4 475 SER 475 487 487 SER SER A . n 
E 4 476 MET 476 488 488 MET MET A . n 
E 4 477 ILE 477 489 489 ILE ILE A . n 
E 4 478 SER 478 490 490 SER SER A . n 
E 4 479 LYS 479 491 491 LYS LYS A . n 
E 4 480 LEU 480 492 492 LEU LEU A . n 
E 4 481 LYS 481 493 493 LYS LYS A . n 
E 4 482 GLN 482 494 494 GLN GLN A . n 
E 4 483 ALA 483 495 495 ALA ALA A . n 
E 4 484 CYS 484 496 496 CYS CYS A . n 
E 4 485 GLY 485 497 ?   ?   ?   A . n 
E 4 486 PHE 486 498 ?   ?   ?   A . n 
E 4 487 GLU 487 499 ?   ?   ?   A . n 
E 4 488 TYR 488 500 ?   ?   ?   A . n 
E 4 489 THR 489 501 ?   ?   ?   A . n 
E 4 490 SER 490 502 ?   ?   ?   A . n 
E 4 491 LYS 491 503 ?   ?   ?   A . n 
E 4 492 LEU 492 504 ?   ?   ?   A . n 
E 4 493 GLN 493 505 ?   ?   ?   A . n 
E 4 494 ARG 494 506 ?   ?   ?   A . n 
E 4 495 MET 495 507 ?   ?   ?   A . n 
E 4 496 PHE 496 508 ?   ?   ?   A . n 
E 4 497 GLN 497 509 ?   ?   ?   A . n 
E 4 498 ASP 498 510 ?   ?   ?   A . n 
E 4 499 ILE 499 511 ?   ?   ?   A . n 
E 4 500 GLY 500 512 ?   ?   ?   A . n 
E 4 501 VAL 501 513 ?   ?   ?   A . n 
E 4 502 SER 502 514 ?   ?   ?   A . n 
E 4 503 LYS 503 515 ?   ?   ?   A . n 
E 4 504 ASP 504 516 ?   ?   ?   A . n 
E 4 505 LEU 505 517 ?   ?   ?   A . n 
E 4 506 ASN 506 518 ?   ?   ?   A . n 
E 4 507 GLU 507 519 ?   ?   ?   A . n 
E 4 508 GLN 508 520 ?   ?   ?   A . n 
E 4 509 PHE 509 521 ?   ?   ?   A . n 
E 4 510 LYS 510 522 ?   ?   ?   A . n 
E 4 511 LYS 511 523 ?   ?   ?   A . n 
E 4 512 HIS 512 524 ?   ?   ?   A . n 
E 4 513 LEU 513 525 ?   ?   ?   A . n 
E 4 514 THR 514 526 ?   ?   ?   A . n 
E 4 515 ASN 515 527 ?   ?   ?   A . n 
E 4 516 SER 516 528 ?   ?   ?   A . n 
E 4 517 GLU 517 529 ?   ?   ?   A . n 
E 4 518 PRO 518 530 ?   ?   ?   A . n 
E 4 519 LEU 519 531 ?   ?   ?   A . n 
E 4 520 ASP 520 532 ?   ?   ?   A . n 
E 4 521 LEU 521 533 ?   ?   ?   A . n 
E 4 522 ASP 522 534 ?   ?   ?   A . n 
E 4 523 PHE 523 535 ?   ?   ?   A . n 
E 4 524 SER 524 536 ?   ?   ?   A . n 
E 4 525 ILE 525 537 ?   ?   ?   A . n 
E 4 526 GLN 526 538 ?   ?   ?   A . n 
E 4 527 VAL 527 539 ?   ?   ?   A . n 
E 4 528 LEU 528 540 ?   ?   ?   A . n 
E 4 529 SER 529 541 ?   ?   ?   A . n 
E 4 530 SER 530 542 ?   ?   ?   A . n 
E 4 531 GLY 531 543 ?   ?   ?   A . n 
E 4 532 SER 532 544 ?   ?   ?   A . n 
E 4 533 TRP 533 545 ?   ?   ?   A . n 
E 4 534 PRO 534 546 ?   ?   ?   A . n 
E 4 535 PHE 535 547 ?   ?   ?   A . n 
E 4 536 GLN 536 548 ?   ?   ?   A . n 
E 4 537 GLN 537 549 ?   ?   ?   A . n 
E 4 538 SER 538 550 ?   ?   ?   A . n 
E 4 539 CYS 539 551 ?   ?   ?   A . n 
E 4 540 THR 540 552 ?   ?   ?   A . n 
E 4 541 PHE 541 553 ?   ?   ?   A . n 
E 4 542 ALA 542 554 ?   ?   ?   A . n 
E 4 543 LEU 543 555 ?   ?   ?   A . n 
E 4 544 PRO 544 556 ?   ?   ?   A . n 
E 4 545 SER 545 557 ?   ?   ?   A . n 
E 4 546 GLU 546 558 ?   ?   ?   A . n 
E 4 547 LEU 547 559 ?   ?   ?   A . n 
E 4 548 GLU 548 560 ?   ?   ?   A . n 
E 4 549 ARG 549 561 ?   ?   ?   A . n 
E 4 550 SER 550 562 ?   ?   ?   A . n 
E 4 551 TYR 551 563 ?   ?   ?   A . n 
E 4 552 GLN 552 564 ?   ?   ?   A . n 
E 4 553 ARG 553 565 ?   ?   ?   A . n 
E 4 554 PHE 554 566 ?   ?   ?   A . n 
E 4 555 THR 555 567 ?   ?   ?   A . n 
E 4 556 ALA 556 568 ?   ?   ?   A . n 
E 4 557 PHE 557 569 ?   ?   ?   A . n 
E 4 558 TYR 558 570 ?   ?   ?   A . n 
E 4 559 ALA 559 571 ?   ?   ?   A . n 
E 4 560 SER 560 572 ?   ?   ?   A . n 
E 4 561 ARG 561 573 ?   ?   ?   A . n 
E 4 562 HIS 562 574 ?   ?   ?   A . n 
E 4 563 SER 563 575 ?   ?   ?   A . n 
E 4 564 GLY 564 576 ?   ?   ?   A . n 
E 4 565 ARG 565 577 ?   ?   ?   A . n 
E 4 566 LYS 566 578 ?   ?   ?   A . n 
E 4 567 LEU 567 579 ?   ?   ?   A . n 
E 4 568 THR 568 580 ?   ?   ?   A . n 
E 4 569 TRP 569 581 ?   ?   ?   A . n 
E 4 570 LEU 570 582 ?   ?   ?   A . n 
E 4 571 TYR 571 583 ?   ?   ?   A . n 
E 4 572 GLN 572 584 ?   ?   ?   A . n 
E 4 573 LEU 573 585 ?   ?   ?   A . n 
E 4 574 SER 574 586 ?   ?   ?   A . n 
E 4 575 LYS 575 587 ?   ?   ?   A . n 
E 4 576 GLY 576 588 ?   ?   ?   A . n 
E 4 577 GLU 577 589 ?   ?   ?   A . n 
E 4 578 LEU 578 590 ?   ?   ?   A . n 
E 4 579 VAL 579 591 ?   ?   ?   A . n 
E 4 580 THR 580 592 ?   ?   ?   A . n 
E 4 581 ASN 581 593 ?   ?   ?   A . n 
E 4 582 CYS 582 594 ?   ?   ?   A . n 
E 4 583 PHE 583 595 ?   ?   ?   A . n 
E 4 584 LYS 584 596 ?   ?   ?   A . n 
E 4 585 ASN 585 597 ?   ?   ?   A . n 
E 4 586 ARG 586 598 ?   ?   ?   A . n 
E 4 587 TYR 587 599 ?   ?   ?   A . n 
E 4 588 THR 588 600 ?   ?   ?   A . n 
E 4 589 LEU 589 601 ?   ?   ?   A . n 
E 4 590 GLN 590 602 ?   ?   ?   A . n 
E 4 591 ALA 591 603 ?   ?   ?   A . n 
E 4 592 SER 592 604 ?   ?   ?   A . n 
E 4 593 THR 593 605 ?   ?   ?   A . n 
E 4 594 PHE 594 606 ?   ?   ?   A . n 
E 4 595 GLN 595 607 ?   ?   ?   A . n 
E 4 596 MET 596 608 ?   ?   ?   A . n 
E 4 597 ALA 597 609 ?   ?   ?   A . n 
E 4 598 ILE 598 610 ?   ?   ?   A . n 
E 4 599 LEU 599 611 ?   ?   ?   A . n 
E 4 600 LEU 600 612 ?   ?   ?   A . n 
E 4 601 GLN 601 613 ?   ?   ?   A . n 
E 4 602 TYR 602 614 ?   ?   ?   A . n 
E 4 603 ASN 603 615 ?   ?   ?   A . n 
E 4 604 THR 604 616 ?   ?   ?   A . n 
E 4 605 GLU 605 617 ?   ?   ?   A . n 
E 4 606 ASP 606 618 ?   ?   ?   A . n 
E 4 607 ALA 607 619 ?   ?   ?   A . n 
E 4 608 TYR 608 620 ?   ?   ?   A . n 
E 4 609 THR 609 621 ?   ?   ?   A . n 
E 4 610 VAL 610 622 ?   ?   ?   A . n 
E 4 611 GLN 611 623 ?   ?   ?   A . n 
E 4 612 GLN 612 624 ?   ?   ?   A . n 
E 4 613 LEU 613 625 ?   ?   ?   A . n 
E 4 614 THR 614 626 ?   ?   ?   A . n 
E 4 615 ASP 615 627 ?   ?   ?   A . n 
E 4 616 SER 616 628 ?   ?   ?   A . n 
E 4 617 THR 617 629 ?   ?   ?   A . n 
E 4 618 GLN 618 630 ?   ?   ?   A . n 
E 4 619 ILE 619 631 ?   ?   ?   A . n 
E 4 620 LYS 620 632 ?   ?   ?   A . n 
E 4 621 MET 621 633 ?   ?   ?   A . n 
E 4 622 ASP 622 634 ?   ?   ?   A . n 
E 4 623 ILE 623 635 ?   ?   ?   A . n 
E 4 624 LEU 624 636 ?   ?   ?   A . n 
E 4 625 ALA 625 637 ?   ?   ?   A . n 
E 4 626 GLN 626 638 ?   ?   ?   A . n 
E 4 627 VAL 627 639 ?   ?   ?   A . n 
E 4 628 LEU 628 640 ?   ?   ?   A . n 
E 4 629 GLN 629 641 ?   ?   ?   A . n 
E 4 630 ILE 630 642 ?   ?   ?   A . n 
E 4 631 LEU 631 643 ?   ?   ?   A . n 
E 4 632 LEU 632 644 ?   ?   ?   A . n 
E 4 633 LYS 633 645 ?   ?   ?   A . n 
E 4 634 SER 634 646 ?   ?   ?   A . n 
E 4 635 LYS 635 647 ?   ?   ?   A . n 
E 4 636 LEU 636 648 ?   ?   ?   A . n 
E 4 637 LEU 637 649 ?   ?   ?   A . n 
E 4 638 VAL 638 650 ?   ?   ?   A . n 
E 4 639 LEU 639 651 ?   ?   ?   A . n 
E 4 640 GLU 640 652 ?   ?   ?   A . n 
E 4 641 ASP 641 653 ?   ?   ?   A . n 
E 4 642 GLU 642 654 ?   ?   ?   A . n 
E 4 643 ASN 643 655 ?   ?   ?   A . n 
E 4 644 ALA 644 656 ?   ?   ?   A . n 
E 4 645 ASN 645 657 ?   ?   ?   A . n 
E 4 646 VAL 646 658 ?   ?   ?   A . n 
E 4 647 ASP 647 659 ?   ?   ?   A . n 
E 4 648 GLU 648 660 ?   ?   ?   A . n 
E 4 649 VAL 649 661 ?   ?   ?   A . n 
E 4 650 GLU 650 662 ?   ?   ?   A . n 
E 4 651 LEU 651 663 ?   ?   ?   A . n 
E 4 652 LYS 652 664 ?   ?   ?   A . n 
E 4 653 PRO 653 665 ?   ?   ?   A . n 
E 4 654 ASP 654 666 ?   ?   ?   A . n 
E 4 655 THR 655 667 ?   ?   ?   A . n 
E 4 656 LEU 656 668 ?   ?   ?   A . n 
E 4 657 ILE 657 669 ?   ?   ?   A . n 
E 4 658 LYS 658 670 ?   ?   ?   A . n 
E 4 659 LEU 659 671 ?   ?   ?   A . n 
E 4 660 TYR 660 672 ?   ?   ?   A . n 
E 4 661 LEU 661 673 ?   ?   ?   A . n 
E 4 662 GLY 662 674 ?   ?   ?   A . n 
E 4 663 TYR 663 675 ?   ?   ?   A . n 
E 4 664 LYS 664 676 ?   ?   ?   A . n 
E 4 665 ASN 665 677 ?   ?   ?   A . n 
E 4 666 LYS 666 678 ?   ?   ?   A . n 
E 4 667 LYS 667 679 ?   ?   ?   A . n 
E 4 668 LEU 668 680 ?   ?   ?   A . n 
E 4 669 ARG 669 681 ?   ?   ?   A . n 
E 4 670 VAL 670 682 ?   ?   ?   A . n 
E 4 671 ASN 671 683 ?   ?   ?   A . n 
E 4 672 ILE 672 684 ?   ?   ?   A . n 
E 4 673 ASN 673 685 ?   ?   ?   A . n 
E 4 674 VAL 674 686 ?   ?   ?   A . n 
E 4 675 PRO 675 687 ?   ?   ?   A . n 
E 4 676 MET 676 688 ?   ?   ?   A . n 
E 4 677 LYS 677 689 ?   ?   ?   A . n 
E 4 678 THR 678 690 ?   ?   ?   A . n 
E 4 679 GLU 679 691 ?   ?   ?   A . n 
E 4 680 GLN 680 692 ?   ?   ?   A . n 
E 4 681 LYS 681 693 ?   ?   ?   A . n 
E 4 682 GLN 682 694 ?   ?   ?   A . n 
E 4 683 GLU 683 695 ?   ?   ?   A . n 
E 4 684 GLN 684 696 ?   ?   ?   A . n 
E 4 685 GLU 685 697 ?   ?   ?   A . n 
E 4 686 THR 686 698 ?   ?   ?   A . n 
E 4 687 THR 687 699 ?   ?   ?   A . n 
E 4 688 HIS 688 700 ?   ?   ?   A . n 
E 4 689 LYS 689 701 ?   ?   ?   A . n 
E 4 690 ASN 690 702 ?   ?   ?   A . n 
E 4 691 ILE 691 703 ?   ?   ?   A . n 
E 4 692 GLU 692 704 ?   ?   ?   A . n 
E 4 693 GLU 693 705 ?   ?   ?   A . n 
E 4 694 ASP 694 706 ?   ?   ?   A . n 
E 4 695 ARG 695 707 ?   ?   ?   A . n 
E 4 696 LYS 696 708 ?   ?   ?   A . n 
E 4 697 LEU 697 709 ?   ?   ?   A . n 
E 4 698 LEU 698 710 ?   ?   ?   A . n 
E 4 699 ILE 699 711 ?   ?   ?   A . n 
E 4 700 GLN 700 712 ?   ?   ?   A . n 
E 4 701 ALA 701 713 ?   ?   ?   A . n 
E 4 702 ALA 702 714 ?   ?   ?   A . n 
E 4 703 ILE 703 715 ?   ?   ?   A . n 
E 4 704 VAL 704 716 ?   ?   ?   A . n 
E 4 705 ARG 705 717 ?   ?   ?   A . n 
E 4 706 ILE 706 718 ?   ?   ?   A . n 
E 4 707 MET 707 719 ?   ?   ?   A . n 
E 4 708 LYS 708 720 ?   ?   ?   A . n 
E 4 709 MET 709 721 ?   ?   ?   A . n 
E 4 710 ARG 710 722 ?   ?   ?   A . n 
E 4 711 LYS 711 723 ?   ?   ?   A . n 
E 4 712 VAL 712 724 ?   ?   ?   A . n 
E 4 713 LEU 713 725 ?   ?   ?   A . n 
E 4 714 LYS 714 726 ?   ?   ?   A . n 
E 4 715 HIS 715 727 ?   ?   ?   A . n 
E 4 716 GLN 716 728 ?   ?   ?   A . n 
E 4 717 GLN 717 729 ?   ?   ?   A . n 
E 4 718 LEU 718 730 ?   ?   ?   A . n 
E 4 719 LEU 719 731 ?   ?   ?   A . n 
E 4 720 GLY 720 732 ?   ?   ?   A . n 
E 4 721 GLU 721 733 ?   ?   ?   A . n 
E 4 722 VAL 722 734 ?   ?   ?   A . n 
E 4 723 LEU 723 735 ?   ?   ?   A . n 
E 4 724 THR 724 736 ?   ?   ?   A . n 
E 4 725 GLN 725 737 ?   ?   ?   A . n 
E 4 726 LEU 726 738 ?   ?   ?   A . n 
E 4 727 SER 727 739 ?   ?   ?   A . n 
E 4 728 SER 728 740 ?   ?   ?   A . n 
E 4 729 ARG 729 741 ?   ?   ?   A . n 
E 4 730 PHE 730 742 ?   ?   ?   A . n 
E 4 731 LYS 731 743 ?   ?   ?   A . n 
E 4 732 PRO 732 744 ?   ?   ?   A . n 
E 4 733 ARG 733 745 ?   ?   ?   A . n 
E 4 734 VAL 734 746 ?   ?   ?   A . n 
E 4 735 PRO 735 747 ?   ?   ?   A . n 
E 4 736 VAL 736 748 ?   ?   ?   A . n 
E 4 737 ILE 737 749 ?   ?   ?   A . n 
E 4 738 LYS 738 750 ?   ?   ?   A . n 
E 4 739 LYS 739 751 ?   ?   ?   A . n 
E 4 740 CYS 740 752 ?   ?   ?   A . n 
E 4 741 ILE 741 753 ?   ?   ?   A . n 
E 4 742 ASP 742 754 ?   ?   ?   A . n 
E 4 743 ILE 743 755 ?   ?   ?   A . n 
E 4 744 LEU 744 756 ?   ?   ?   A . n 
E 4 745 ILE 745 757 ?   ?   ?   A . n 
E 4 746 GLU 746 758 ?   ?   ?   A . n 
E 4 747 LYS 747 759 ?   ?   ?   A . n 
E 4 748 GLU 748 760 ?   ?   ?   A . n 
E 4 749 TYR 749 761 ?   ?   ?   A . n 
E 4 750 LEU 750 762 ?   ?   ?   A . n 
E 4 751 GLU 751 763 ?   ?   ?   A . n 
E 4 752 ARG 752 764 ?   ?   ?   A . n 
E 4 753 VAL 753 765 ?   ?   ?   A . n 
E 4 754 ASP 754 766 ?   ?   ?   A . n 
E 4 755 GLY 755 767 ?   ?   ?   A . n 
E 4 756 GLU 756 768 ?   ?   ?   A . n 
E 4 757 LYS 757 769 ?   ?   ?   A . n 
E 4 758 ASP 758 770 ?   ?   ?   A . n 
E 4 759 THR 759 771 ?   ?   ?   A . n 
E 4 760 TYR 760 772 ?   ?   ?   A . n 
E 4 761 SER 761 773 ?   ?   ?   A . n 
E 4 762 TYR 762 774 ?   ?   ?   A . n 
E 4 763 LEU 763 775 ?   ?   ?   A . n 
E 4 764 ALA 764 776 ?   ?   ?   A . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A GLU 148 ? CB  ? E GLU 136 CB  
2 1 Y 1 A GLU 148 ? CG  ? E GLU 136 CG  
3 1 Y 1 A GLU 148 ? CD  ? E GLU 136 CD  
4 1 Y 1 A GLU 148 ? OE1 ? E GLU 136 OE1 
5 1 Y 1 A GLU 148 ? OE2 ? E GLU 136 OE2 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UA6 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8UA6 
_struct.title                        'Cryo-EM Structure of SCF-FBOX22-BACH1BTB' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UA6 
_struct_keywords.text            'F-box protein, FBXO22, BACH1, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP FBX22_HUMAN Q8NEZ5 ?        1 
;MEPVGCCGECRGSSVDPRSTFVLSNLAEVVERVLTFLPAKALLRVACVCRLWRECVRRVLRTHRSVTWISAGLAEAGHLE
GHCLVRVVAEELENVRILPHTVLYMADSETFISLEECRGHKRARKRTSMETALALEKLFPKQCQVLGIVTPGIVVTPMGS
GSNRPQEIEIGESGFALLFPQIEGIKIQPFHFIKDPKNLTLERHQLTEVGLLDNPELRVVLVFGYNCCKVGASNYLQQVV
STFSDMNIILAGGQVDNLSSLTSEKNPLDIDASGVVGLSFSGHRIQSATVLLNEDVSDEKTAEAAMQRLKAANIPEHNTI
GFMFACVGRGFQYYRAKGNVEADAFRKFFPSVPLFGFFGNGEIGCDRIVTGNFILRKCNEVKDDDLFHSYTTIMALIHLG
SSK
;
1  
2 UNP BACH1_HUMAN O14867 ?        2 
;SVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP
LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKF
;
7  
3 UNP SKP1_HUMAN  P63208 P63208-2 3 
;MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEK
RTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVGSTQFCL

;
1  
4 UNP CUL1_HUMAN  Q13616 ?        4 
;KQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRL
KEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLF
RPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFL
QQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDG
LGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMA
QSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKL
KQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYAS
RHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLE
DENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLG
EVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA
;
13 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UA6 C 1 ? 403 ? Q8NEZ5 1  ? 403 ? 1  403 
2 2 8UA6 D 1 ? 122 ? O14867 7  ? 128 ? 7  128 
3 2 8UA6 E 1 ? 122 ? O14867 7  ? 128 ? 7  128 
4 3 8UA6 B 1 ? 160 ? P63208 1  ? 160 ? 1  160 
5 4 8UA6 A 1 ? 764 ? Q13616 13 ? 776 ? 13 776 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PHE A 21  ? LEU A 26  ? PHE C 21  LEU C 26  1 ? 6  
HELX_P HELX_P2  AA2 LEU A 26  ? THR A 35  ? LEU C 26  THR C 35  1 ? 10 
HELX_P HELX_P3  AA3 PRO A 38  ? LEU A 43  ? PRO C 38  LEU C 43  1 ? 6  
HELX_P HELX_P4  AA4 ARG A 44  ? VAL A 48  ? ARG C 44  VAL C 48  5 ? 5  
HELX_P HELX_P5  AA5 CYS A 49  ? LEU A 60  ? CYS C 49  LEU C 60  1 ? 12 
HELX_P HELX_P6  AA6 GLY A 72  ? ALA A 76  ? GLY C 72  ALA C 76  5 ? 5  
HELX_P HELX_P7  AA7 HIS A 82  ? LEU A 92  ? HIS C 82  LEU C 92  1 ? 11 
HELX_P HELX_P8  AA8 GLU A 93  ? VAL A 95  ? GLU C 93  VAL C 95  5 ? 3  
HELX_P HELX_P9  AA9 SER A 128 ? PHE A 139 ? SER C 128 PHE C 139 1 ? 12 
HELX_P HELX_P10 AB1 HIS A 204 ? VAL A 209 ? HIS C 204 VAL C 209 1 ? 6  
HELX_P HELX_P11 AB2 GLY A 231 ? SER A 244 ? GLY C 231 SER C 244 1 ? 14 
HELX_P HELX_P12 AB3 ASP A 298 ? ALA A 311 ? ASP C 298 ALA C 311 1 ? 14 
HELX_P HELX_P13 AB4 ASN A 339 ? PHE A 349 ? ASN C 339 PHE C 349 1 ? 11 
HELX_P HELX_P14 AB5 VAL B 9   ? LYS B 24  ? VAL D 15  LYS D 30  1 ? 16 
HELX_P HELX_P15 AB6 HIS B 42  ? SER B 50  ? HIS D 48  SER D 56  1 ? 9  
HELX_P HELX_P16 AB7 THR B 74  ? ALA B 88  ? THR D 80  ALA D 94  1 ? 15 
HELX_P HELX_P17 AB8 GLU B 95  ? PHE B 106 ? GLU D 101 PHE D 112 1 ? 12 
HELX_P HELX_P18 AB9 VAL C 9   ? LYS C 23  ? VAL E 15  LYS E 29  1 ? 15 
HELX_P HELX_P19 AC1 VAL C 45  ? SER C 50  ? VAL E 51  SER E 56  1 ? 6  
HELX_P HELX_P20 AC2 SER C 51  ? VAL C 58  ? SER E 57  VAL E 64  1 ? 8  
HELX_P HELX_P21 AC3 PHE C 78  ? ALA C 88  ? PHE E 84  ALA E 94  1 ? 11 
HELX_P HELX_P22 AC4 ASN C 96  ? SER C 108 ? ASN E 102 SER E 114 1 ? 13 
HELX_P HELX_P23 AC5 ASP D 17  ? LYS D 22  ? ASP B 17  LYS B 22  1 ? 6  
HELX_P HELX_P24 AC6 SER D 24  ? ASP D 33  ? SER B 24  ASP B 33  1 ? 10 
HELX_P HELX_P25 AC7 ASN D 51  ? HIS D 65  ? ASN B 51  HIS B 65  1 ? 15 
HELX_P HELX_P26 AC8 PRO D 86  ? LYS D 94  ? PRO B 86  LYS B 94  1 ? 9  
HELX_P HELX_P27 AC9 ASP D 96  ? ASP D 111 ? ASP B 96  ASP B 111 1 ? 16 
HELX_P HELX_P28 AD1 ILE D 112 ? LYS D 128 ? ILE B 112 LYS B 128 1 ? 17 
HELX_P HELX_P29 AD2 PRO D 132 ? GLU D 134 ? PRO B 132 GLU B 134 5 ? 3  
HELX_P HELX_P30 AD3 ILE D 135 ? ASN D 140 ? ILE B 135 ASN B 140 1 ? 6  
HELX_P HELX_P31 AD4 THR D 146 ? GLY D 154 ? THR B 146 GLY B 154 1 ? 9  
HELX_P HELX_P32 AD5 GLN E 7   ? GLY E 15  ? GLN A 19  GLY A 27  5 ? 9  
HELX_P HELX_P33 AD6 ALA E 26  ? THR E 42  ? ALA A 38  THR A 54  1 ? 17 
HELX_P HELX_P34 AD7 LEU E 74  ? PHE E 83  ? LEU A 86  PHE A 95  1 ? 10 
HELX_P HELX_P35 AD8 PHE E 83  ? LEU E 88  ? PHE A 95  LEU A 100 1 ? 6  
HELX_P HELX_P36 AD9 TRP E 111 ? PHE E 116 ? TRP A 123 PHE A 128 1 ? 6  
HELX_P HELX_P37 AE1 SER E 117 ? VAL E 120 ? SER A 129 VAL A 132 5 ? 4  
HELX_P HELX_P38 AE2 ALA E 126 ? HIS E 131 ? ALA A 138 HIS A 143 1 ? 6  
HELX_P HELX_P39 AE3 GLU E 146 ? TRP E 155 ? GLU A 158 TRP A 167 1 ? 10 
HELX_P HELX_P40 AE4 VAL E 167 ? GLU E 176 ? VAL A 179 GLU A 188 1 ? 10 
HELX_P HELX_P41 AE5 ASN E 185 ? LEU E 199 ? ASN A 197 LEU A 211 1 ? 15 
HELX_P HELX_P42 AE6 LEU E 213 ? GLU E 221 ? LEU A 225 GLU A 233 1 ? 9  
HELX_P HELX_P43 AE7 GLU E 221 ? ARG E 230 ? GLU A 233 ARG A 242 1 ? 10 
HELX_P HELX_P44 AE8 GLU E 235 ? LEU E 240 ? GLU A 247 LEU A 252 1 ? 6  
HELX_P HELX_P45 AE9 PRO E 244 ? GLU E 259 ? PRO A 256 GLU A 271 1 ? 16 
HELX_P HELX_P46 AF1 THR E 271 ? ALA E 276 ? THR A 283 ALA A 288 1 ? 6  
HELX_P HELX_P47 AF2 ARG E 277 ? GLU E 280 ? ARG A 289 GLU A 292 5 ? 4  
HELX_P HELX_P48 AF3 PHE E 291 ? ALA E 301 ? PHE A 303 ALA A 313 1 ? 11 
HELX_P HELX_P49 AF4 GLU E 305 ? ILE E 317 ? GLU A 317 ILE A 329 1 ? 13 
HELX_P HELX_P50 AF5 LYS E 325 ? CYS E 343 ? LYS A 337 CYS A 355 1 ? 19 
HELX_P HELX_P51 AF6 GLU E 345 ? ASN E 349 ? GLU A 357 ASN A 361 5 ? 5  
HELX_P HELX_P52 AF7 ASP E 350 ? VAL E 369 ? ASP A 362 VAL A 381 1 ? 20 
HELX_P HELX_P53 AF8 ASP E 376 ? ASP E 384 ? ASP A 388 ASP A 396 1 ? 9  
HELX_P HELX_P54 AF9 CYS E 387 ? ILE E 391 ? CYS A 399 ILE A 403 5 ? 5  
HELX_P HELX_P55 AG1 SER E 404 ? LEU E 418 ? SER A 416 LEU A 430 1 ? 15 
HELX_P HELX_P56 AG2 GLU E 426 ? LYS E 442 ? GLU A 438 LYS A 454 1 ? 17 
HELX_P HELX_P57 AG3 LYS E 447 ? GLN E 465 ? LYS A 459 GLN A 477 1 ? 19 
HELX_P HELX_P58 AG4 SER E 469 ? ALA E 483 ? SER A 481 ALA A 495 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
AA9 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? parallel      
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 67  ? ALA A 71  ? THR C 67  ALA C 71  
AA1 2 GLY A 174 ? PHE A 179 ? GLY C 174 PHE C 179 
AA1 3 THR A 101 ? ALA A 106 ? THR C 101 ALA C 106 
AA1 4 GLN A 144 ? VAL A 149 ? GLN C 144 VAL C 149 
AA1 5 ASN A 257 ? LEU A 261 ? ASN C 257 LEU C 261 
AA2 1 GLN A 166 ? ILE A 168 ? GLN C 166 ILE C 168 
AA2 2 ILE A 153 ? VAL A 155 ? ILE C 153 VAL C 155 
AA2 3 LEU A 354 ? GLY A 359 ? LEU C 354 GLY C 359 
AA2 4 ILE A 320 ? CYS A 326 ? ILE C 320 CYS C 326 
AA2 5 THR A 392 ? ILE A 397 ? THR C 392 ILE C 397 
AA2 6 LEU A 291 ? LEU A 292 ? LEU C 291 LEU C 292 
AA3 1 PHE A 190 ? ILE A 193 ? PHE C 190 ILE C 193 
AA3 2 GLY A 274 ? GLY A 277 ? GLY C 274 GLY C 277 
AA3 3 PHE A 223 ? TYR A 225 ? PHE C 223 TYR C 225 
AA3 4 GLN A 254 ? VAL A 255 ? GLN C 254 VAL C 255 
AA4 1 LEU A 217 ? VAL A 220 ? LEU C 217 VAL C 220 
AA4 2 SER A 279 ? SER A 281 ? SER C 279 SER C 281 
AA5 1 GLU A 362 ? ILE A 363 ? GLU C 362 ILE C 363 
AA5 2 PHE A 387 ? HIS A 388 ? PHE C 387 HIS C 388 
AA6 1 PHE A 373 ? ILE A 374 ? PHE C 373 ILE C 374 
AA6 2 GLU C 6   ? SER C 7   ? GLU E 12  SER E 13  
AA7 1 PHE B 39  ? ALA B 41  ? PHE D 45  ALA D 47  
AA7 2 VAL B 30  ? VAL B 34  ? VAL D 36  VAL D 40  
AA7 3 ASN B 66  ? LEU B 69  ? ASN D 72  LEU D 75  
AA8 1 VAL C 30  ? VAL C 34  ? VAL E 36  VAL E 40  
AA8 2 GLN C 37  ? ALA C 41  ? GLN E 43  ALA E 47  
AA9 1 ILE D 13  ? VAL D 16  ? ILE B 13  VAL B 16  
AA9 2 ILE D 4   ? GLN D 7   ? ILE B 4   GLN B 7   
AA9 3 VAL D 45  ? PRO D 46  ? VAL B 45  PRO B 46  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 69  ? N ILE C 69  O ALA A 176 ? O ALA C 176 
AA1 2 3 O PHE A 179 ? O PHE C 179 N THR A 101 ? N THR C 101 
AA1 3 4 N VAL A 102 ? N VAL C 102 O GLN A 144 ? O GLN C 144 
AA1 4 5 N GLY A 147 ? N GLY C 147 O SER A 259 ? O SER C 259 
AA2 1 2 O GLN A 166 ? O GLN C 166 N VAL A 155 ? N VAL C 155 
AA2 2 3 N VAL A 154 ? N VAL C 154 O GLY A 356 ? O GLY C 356 
AA2 3 4 O GLY A 359 ? O GLY C 359 N ALA A 325 ? N ALA C 325 
AA2 4 5 N PHE A 324 ? N PHE C 324 O ILE A 393 ? O ILE C 393 
AA2 5 6 O THR A 392 ? O THR C 392 N LEU A 292 ? N LEU C 292 
AA3 1 2 N PHE A 192 ? N PHE C 192 O VAL A 275 ? O VAL C 275 
AA3 2 3 O VAL A 276 ? O VAL C 276 N PHE A 223 ? N PHE C 223 
AA3 3 4 N GLY A 224 ? N GLY C 224 O VAL A 255 ? O VAL C 255 
AA4 1 2 N VAL A 219 ? N VAL C 219 O PHE A 280 ? O PHE C 280 
AA5 1 2 N GLU A 362 ? N GLU C 362 O HIS A 388 ? O HIS C 388 
AA6 1 2 N ILE A 374 ? N ILE C 374 O GLU C 6   ? O GLU E 12  
AA7 1 2 O PHE B 39  ? O PHE D 45  N ILE B 32  ? N ILE D 38  
AA7 2 3 N PHE B 33  ? N PHE D 39  O LEU B 69  ? O LEU D 75  
AA8 1 2 N ILE C 32  ? N ILE E 38  O PHE C 39  ? O PHE E 45  
AA9 1 2 O PHE D 14  ? O PHE B 14  N LEU D 6   ? N LEU B 6   
AA9 2 3 N GLN D 7   ? N GLN B 7   O VAL D 45  ? O VAL B 45  
# 
_pdbx_entry_details.entry_id                   8UA6 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OG 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   SER 
_pdbx_validate_close_contact.auth_seq_id_1    8 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OD1 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   ASP 
_pdbx_validate_close_contact.auth_seq_id_2    10 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.14 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CG 
_pdbx_validate_rmsd_bond.auth_asym_id_1            D 
_pdbx_validate_rmsd_bond.auth_comp_id_1            PRO 
_pdbx_validate_rmsd_bond.auth_seq_id_1             86 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_2            D 
_pdbx_validate_rmsd_bond.auth_comp_id_2            PRO 
_pdbx_validate_rmsd_bond.auth_seq_id_2             86 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.157 
_pdbx_validate_rmsd_bond.bond_target_value         1.502 
_pdbx_validate_rmsd_bond.bond_deviation            -0.345 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.033 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA D PRO 86  ? ? N  D PRO 86  ? ? CD D PRO 86  ? ? 94.95  111.70 -16.75 1.40 N 
2 1 CA D PRO 86  ? ? CB D PRO 86  ? ? CG D PRO 86  ? ? 92.33  104.80 -12.47 1.90 N 
3 1 N  D PRO 86  ? ? CD D PRO 86  ? ? CG D PRO 86  ? ? 85.24  103.20 -17.96 1.50 N 
4 1 N  B ASP 144 ? ? CA B ASP 144 ? ? C  B ASP 144 ? ? 130.14 111.00 19.14  2.70 N 
5 1 C  A ARG 173 ? ? N  A PRO 174 ? ? CD A PRO 174 ? ? 113.58 128.40 -14.82 2.10 Y 
6 1 CA A LEU 252 ? ? CB A LEU 252 ? ? CG A LEU 252 ? ? 134.70 115.30 19.40  2.30 N 
7 1 CA A LEU 430 ? ? CB A LEU 430 ? ? CG A LEU 430 ? ? 131.20 115.30 15.90  2.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO C 17  ? ? -59.65  170.42  
2  1 ARG C 32  ? ? -87.70  46.22   
3  1 VAL C 33  ? ? -130.45 -50.69  
4  1 PHE C 36  ? ? -97.29  56.38   
5  1 THR C 62  ? ? -91.95  50.47   
6  1 SER C 108 ? ? -94.54  36.16   
7  1 GLU C 115 ? ? -140.17 -15.16  
8  1 ASN C 198 ? ? -163.00 -169.22 
9  1 THR C 200 ? ? -99.57  -68.92  
10 1 LEU C 201 ? ? -164.63 109.64  
11 1 GLU C 202 ? ? -69.63  -74.55  
12 1 ARG C 203 ? ? -150.35 -27.42  
13 1 ASP C 213 ? ? 58.58   19.82   
14 1 ASN C 247 ? ? -94.51  57.17   
15 1 LYS C 265 ? ? -141.03 12.05   
16 1 ASN C 293 ? ? -78.84  -167.59 
17 1 ASN C 379 ? ? 36.33   51.48   
18 1 VAL C 381 ? ? -83.25  -78.19  
19 1 LYS C 382 ? ? -135.21 -68.15  
20 1 ASP C 383 ? ? -151.30 30.40   
21 1 ALA D 10  ? ? 65.47   121.52  
22 1 GLU D 41  ? ? 49.29   -122.73 
23 1 GLN D 124 ? ? -82.26  49.58   
24 1 ASP E 31  ? ? 36.40   -74.54  
25 1 GLU E 41  ? ? 59.17   19.41   
26 1 GLU E 77  ? ? -141.86 -24.48  
27 1 ALA E 94  ? ? 70.75   37.27   
28 1 GLU E 120 ? ? -69.65  8.43    
29 1 PRO B 48  ? ? -91.43  45.23   
30 1 ILE B 85  ? ? 41.20   77.15   
31 1 PRO B 86  ? ? -43.04  153.77  
32 1 ASP B 111 ? ? 56.93   78.63   
33 1 PHE B 145 ? ? 62.58   130.75  
34 1 THR B 146 ? ? -13.65  106.90  
35 1 VAL B 153 ? ? -121.01 -64.40  
36 1 SER B 155 ? ? -153.45 21.34   
37 1 GLN B 157 ? ? -160.71 -122.10 
38 1 PHE B 158 ? ? 51.30   -117.86 
39 1 CYS B 159 ? ? 43.63   -136.74 
40 1 ILE A 15  ? ? -109.96 -61.16  
41 1 TRP A 21  ? ? -85.78  46.60   
42 1 ARG A 25  ? ? -82.67  48.40   
43 1 PHE A 83  ? ? 43.78   26.31   
44 1 VAL A 84  ? ? 29.24   55.91   
45 1 GLN A 122 ? ? -91.98  48.11   
46 1 SER A 130 ? ? -87.70  48.39   
47 1 CYS A 137 ? ? -93.71  51.80   
48 1 VAL A 145 ? ? 149.37  -20.17  
49 1 GLU A 151 ? ? -178.10 -105.38 
50 1 LEU A 164 ? ? -92.93  45.77   
51 1 ARG A 168 ? ? -84.20  47.17   
52 1 PHE A 172 ? ? -81.95  44.72   
53 1 PRO A 174 ? ? 2.67    -138.47 
54 1 LEU A 175 ? ? 53.47   -74.03  
55 1 ASN A 192 ? ? -130.43 -34.22  
56 1 LEU A 211 ? ? -67.43  7.46    
57 1 ASP A 216 ? ? 64.49   -145.66 
58 1 ASP A 217 ? ? 50.03   -126.53 
59 1 GLN A 235 ? ? -93.58  47.80   
60 1 THR A 245 ? ? -92.67  46.50   
61 1 THR A 249 ? ? -87.16  46.71   
62 1 GLU A 250 ? ? -140.42 -12.92  
63 1 LEU A 252 ? ? -86.89  47.82   
64 1 GLN A 253 ? ? -143.84 -7.32   
65 1 GLU A 271 ? ? -85.50  44.68   
66 1 GLN A 272 ? ? -142.70 -0.91   
67 1 VAL A 277 ? ? 158.43  -1.34   
68 1 LEU A 279 ? ? -143.55 -157.21 
69 1 HIS A 280 ? ? 82.76   1.14    
70 1 GLU A 281 ? ? 57.46   -149.84 
71 1 SER A 282 ? ? 58.85   18.76   
72 1 LYS A 290 ? ? -83.05  45.03   
73 1 GLU A 297 ? ? -150.85 -10.63  
74 1 LEU A 300 ? ? -80.79  46.95   
75 1 PHE A 303 ? ? -135.07 -37.51  
76 1 LEU A 336 ? ? -82.42  46.99   
77 1 LEU A 349 ? ? -85.20  47.31   
78 1 ALA A 350 ? ? -131.97 -37.10  
79 1 HIS A 374 ? ? -91.62  45.24   
80 1 PHE A 385 ? ? -93.35  48.85   
81 1 ASN A 386 ? ? 38.99   38.47   
82 1 ASP A 396 ? ? -79.07  -149.99 
83 1 LYS A 397 ? ? -26.22  -30.14  
84 1 VAL A 408 ? ? 61.47   -56.28  
85 1 GLN A 413 ? ? -57.25  106.12  
86 1 SER A 414 ? ? -166.23 116.07  
87 1 GLU A 457 ? ? 66.11   -3.62   
88 1 ALA A 495 ? ? -79.66  -165.31 
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 TYR A 278 ? ? LEU A 279 ? ? -137.26 
2 1 ILE A 296 ? ? GLU A 297 ? ? 149.85  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8UA6 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8UA6 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'BACK PROJECTION' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.9 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               413523 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 FBXO22-BACH1BTB 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2 
# 
_em_imaging.entry_id                        8UA6 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             3500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              8UA6 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8UA6 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 C MET 1   ? A MET 1   
2   1 Y 1 C GLU 2   ? A GLU 2   
3   1 Y 1 C PRO 3   ? A PRO 3   
4   1 Y 1 C VAL 4   ? A VAL 4   
5   1 Y 1 C GLY 5   ? A GLY 5   
6   1 Y 1 C CYS 6   ? A CYS 6   
7   1 Y 1 C CYS 7   ? A CYS 7   
8   1 Y 1 C GLY 8   ? A GLY 8   
9   1 Y 1 C GLU 9   ? A GLU 9   
10  1 Y 1 C CYS 10  ? A CYS 10  
11  1 Y 1 C ARG 11  ? A ARG 11  
12  1 Y 1 C GLY 12  ? A GLY 12  
13  1 Y 1 C SER 13  ? A SER 13  
14  1 Y 1 C SER 14  ? A SER 14  
15  1 Y 1 C VAL 15  ? A VAL 15  
16  1 Y 1 C CYS 117 ? A CYS 117 
17  1 Y 1 C ARG 118 ? A ARG 118 
18  1 Y 1 C GLY 119 ? A GLY 119 
19  1 Y 1 C HIS 120 ? A HIS 120 
20  1 Y 1 C LYS 121 ? A LYS 121 
21  1 Y 1 C ARG 122 ? A ARG 122 
22  1 Y 1 C ALA 123 ? A ALA 123 
23  1 Y 1 C ARG 124 ? A ARG 124 
24  1 Y 1 C LYS 125 ? A LYS 125 
25  1 Y 1 C ARG 126 ? A ARG 126 
26  1 Y 1 C SER 402 ? A SER 402 
27  1 Y 1 C LYS 403 ? A LYS 403 
28  1 Y 1 E PHE 128 ? C PHE 122 
29  1 Y 1 B MET 1   ? D MET 1   
30  1 Y 1 B PRO 72  ? D PRO 72  
31  1 Y 1 B GLU 73  ? D GLU 73  
32  1 Y 1 B ASP 74  ? D ASP 74  
33  1 Y 1 B ASP 75  ? D ASP 75  
34  1 Y 1 B GLU 76  ? D GLU 76  
35  1 Y 1 A GLN 58  ? E GLN 46  
36  1 Y 1 A SER 59  ? E SER 47  
37  1 Y 1 A ASN 60  ? E ASN 48  
38  1 Y 1 A GLN 61  ? E GLN 49  
39  1 Y 1 A ALA 62  ? E ALA 50  
40  1 Y 1 A ARG 63  ? E ARG 51  
41  1 Y 1 A GLY 64  ? E GLY 52  
42  1 Y 1 A ALA 65  ? E ALA 53  
43  1 Y 1 A GLY 66  ? E GLY 54  
44  1 Y 1 A VAL 67  ? E VAL 55  
45  1 Y 1 A PRO 68  ? E PRO 56  
46  1 Y 1 A PRO 69  ? E PRO 57  
47  1 Y 1 A SER 70  ? E SER 58  
48  1 Y 1 A LYS 71  ? E LYS 59  
49  1 Y 1 A SER 72  ? E SER 60  
50  1 Y 1 A LYS 73  ? E LYS 61  
51  1 Y 1 A LYS 74  ? E LYS 62  
52  1 Y 1 A GLY 75  ? E GLY 63  
53  1 Y 1 A GLN 76  ? E GLN 64  
54  1 Y 1 A THR 77  ? E THR 65  
55  1 Y 1 A PRO 78  ? E PRO 66  
56  1 Y 1 A GLY 79  ? E GLY 67  
57  1 Y 1 A GLY 80  ? E GLY 68  
58  1 Y 1 A ALA 81  ? E ALA 69  
59  1 Y 1 A LYS 221 ? E LYS 209 
60  1 Y 1 A GLY 497 ? E GLY 485 
61  1 Y 1 A PHE 498 ? E PHE 486 
62  1 Y 1 A GLU 499 ? E GLU 487 
63  1 Y 1 A TYR 500 ? E TYR 488 
64  1 Y 1 A THR 501 ? E THR 489 
65  1 Y 1 A SER 502 ? E SER 490 
66  1 Y 1 A LYS 503 ? E LYS 491 
67  1 Y 1 A LEU 504 ? E LEU 492 
68  1 Y 1 A GLN 505 ? E GLN 493 
69  1 Y 1 A ARG 506 ? E ARG 494 
70  1 Y 1 A MET 507 ? E MET 495 
71  1 Y 1 A PHE 508 ? E PHE 496 
72  1 Y 1 A GLN 509 ? E GLN 497 
73  1 Y 1 A ASP 510 ? E ASP 498 
74  1 Y 1 A ILE 511 ? E ILE 499 
75  1 Y 1 A GLY 512 ? E GLY 500 
76  1 Y 1 A VAL 513 ? E VAL 501 
77  1 Y 1 A SER 514 ? E SER 502 
78  1 Y 1 A LYS 515 ? E LYS 503 
79  1 Y 1 A ASP 516 ? E ASP 504 
80  1 Y 1 A LEU 517 ? E LEU 505 
81  1 Y 1 A ASN 518 ? E ASN 506 
82  1 Y 1 A GLU 519 ? E GLU 507 
83  1 Y 1 A GLN 520 ? E GLN 508 
84  1 Y 1 A PHE 521 ? E PHE 509 
85  1 Y 1 A LYS 522 ? E LYS 510 
86  1 Y 1 A LYS 523 ? E LYS 511 
87  1 Y 1 A HIS 524 ? E HIS 512 
88  1 Y 1 A LEU 525 ? E LEU 513 
89  1 Y 1 A THR 526 ? E THR 514 
90  1 Y 1 A ASN 527 ? E ASN 515 
91  1 Y 1 A SER 528 ? E SER 516 
92  1 Y 1 A GLU 529 ? E GLU 517 
93  1 Y 1 A PRO 530 ? E PRO 518 
94  1 Y 1 A LEU 531 ? E LEU 519 
95  1 Y 1 A ASP 532 ? E ASP 520 
96  1 Y 1 A LEU 533 ? E LEU 521 
97  1 Y 1 A ASP 534 ? E ASP 522 
98  1 Y 1 A PHE 535 ? E PHE 523 
99  1 Y 1 A SER 536 ? E SER 524 
100 1 Y 1 A ILE 537 ? E ILE 525 
101 1 Y 1 A GLN 538 ? E GLN 526 
102 1 Y 1 A VAL 539 ? E VAL 527 
103 1 Y 1 A LEU 540 ? E LEU 528 
104 1 Y 1 A SER 541 ? E SER 529 
105 1 Y 1 A SER 542 ? E SER 530 
106 1 Y 1 A GLY 543 ? E GLY 531 
107 1 Y 1 A SER 544 ? E SER 532 
108 1 Y 1 A TRP 545 ? E TRP 533 
109 1 Y 1 A PRO 546 ? E PRO 534 
110 1 Y 1 A PHE 547 ? E PHE 535 
111 1 Y 1 A GLN 548 ? E GLN 536 
112 1 Y 1 A GLN 549 ? E GLN 537 
113 1 Y 1 A SER 550 ? E SER 538 
114 1 Y 1 A CYS 551 ? E CYS 539 
115 1 Y 1 A THR 552 ? E THR 540 
116 1 Y 1 A PHE 553 ? E PHE 541 
117 1 Y 1 A ALA 554 ? E ALA 542 
118 1 Y 1 A LEU 555 ? E LEU 543 
119 1 Y 1 A PRO 556 ? E PRO 544 
120 1 Y 1 A SER 557 ? E SER 545 
121 1 Y 1 A GLU 558 ? E GLU 546 
122 1 Y 1 A LEU 559 ? E LEU 547 
123 1 Y 1 A GLU 560 ? E GLU 548 
124 1 Y 1 A ARG 561 ? E ARG 549 
125 1 Y 1 A SER 562 ? E SER 550 
126 1 Y 1 A TYR 563 ? E TYR 551 
127 1 Y 1 A GLN 564 ? E GLN 552 
128 1 Y 1 A ARG 565 ? E ARG 553 
129 1 Y 1 A PHE 566 ? E PHE 554 
130 1 Y 1 A THR 567 ? E THR 555 
131 1 Y 1 A ALA 568 ? E ALA 556 
132 1 Y 1 A PHE 569 ? E PHE 557 
133 1 Y 1 A TYR 570 ? E TYR 558 
134 1 Y 1 A ALA 571 ? E ALA 559 
135 1 Y 1 A SER 572 ? E SER 560 
136 1 Y 1 A ARG 573 ? E ARG 561 
137 1 Y 1 A HIS 574 ? E HIS 562 
138 1 Y 1 A SER 575 ? E SER 563 
139 1 Y 1 A GLY 576 ? E GLY 564 
140 1 Y 1 A ARG 577 ? E ARG 565 
141 1 Y 1 A LYS 578 ? E LYS 566 
142 1 Y 1 A LEU 579 ? E LEU 567 
143 1 Y 1 A THR 580 ? E THR 568 
144 1 Y 1 A TRP 581 ? E TRP 569 
145 1 Y 1 A LEU 582 ? E LEU 570 
146 1 Y 1 A TYR 583 ? E TYR 571 
147 1 Y 1 A GLN 584 ? E GLN 572 
148 1 Y 1 A LEU 585 ? E LEU 573 
149 1 Y 1 A SER 586 ? E SER 574 
150 1 Y 1 A LYS 587 ? E LYS 575 
151 1 Y 1 A GLY 588 ? E GLY 576 
152 1 Y 1 A GLU 589 ? E GLU 577 
153 1 Y 1 A LEU 590 ? E LEU 578 
154 1 Y 1 A VAL 591 ? E VAL 579 
155 1 Y 1 A THR 592 ? E THR 580 
156 1 Y 1 A ASN 593 ? E ASN 581 
157 1 Y 1 A CYS 594 ? E CYS 582 
158 1 Y 1 A PHE 595 ? E PHE 583 
159 1 Y 1 A LYS 596 ? E LYS 584 
160 1 Y 1 A ASN 597 ? E ASN 585 
161 1 Y 1 A ARG 598 ? E ARG 586 
162 1 Y 1 A TYR 599 ? E TYR 587 
163 1 Y 1 A THR 600 ? E THR 588 
164 1 Y 1 A LEU 601 ? E LEU 589 
165 1 Y 1 A GLN 602 ? E GLN 590 
166 1 Y 1 A ALA 603 ? E ALA 591 
167 1 Y 1 A SER 604 ? E SER 592 
168 1 Y 1 A THR 605 ? E THR 593 
169 1 Y 1 A PHE 606 ? E PHE 594 
170 1 Y 1 A GLN 607 ? E GLN 595 
171 1 Y 1 A MET 608 ? E MET 596 
172 1 Y 1 A ALA 609 ? E ALA 597 
173 1 Y 1 A ILE 610 ? E ILE 598 
174 1 Y 1 A LEU 611 ? E LEU 599 
175 1 Y 1 A LEU 612 ? E LEU 600 
176 1 Y 1 A GLN 613 ? E GLN 601 
177 1 Y 1 A TYR 614 ? E TYR 602 
178 1 Y 1 A ASN 615 ? E ASN 603 
179 1 Y 1 A THR 616 ? E THR 604 
180 1 Y 1 A GLU 617 ? E GLU 605 
181 1 Y 1 A ASP 618 ? E ASP 606 
182 1 Y 1 A ALA 619 ? E ALA 607 
183 1 Y 1 A TYR 620 ? E TYR 608 
184 1 Y 1 A THR 621 ? E THR 609 
185 1 Y 1 A VAL 622 ? E VAL 610 
186 1 Y 1 A GLN 623 ? E GLN 611 
187 1 Y 1 A GLN 624 ? E GLN 612 
188 1 Y 1 A LEU 625 ? E LEU 613 
189 1 Y 1 A THR 626 ? E THR 614 
190 1 Y 1 A ASP 627 ? E ASP 615 
191 1 Y 1 A SER 628 ? E SER 616 
192 1 Y 1 A THR 629 ? E THR 617 
193 1 Y 1 A GLN 630 ? E GLN 618 
194 1 Y 1 A ILE 631 ? E ILE 619 
195 1 Y 1 A LYS 632 ? E LYS 620 
196 1 Y 1 A MET 633 ? E MET 621 
197 1 Y 1 A ASP 634 ? E ASP 622 
198 1 Y 1 A ILE 635 ? E ILE 623 
199 1 Y 1 A LEU 636 ? E LEU 624 
200 1 Y 1 A ALA 637 ? E ALA 625 
201 1 Y 1 A GLN 638 ? E GLN 626 
202 1 Y 1 A VAL 639 ? E VAL 627 
203 1 Y 1 A LEU 640 ? E LEU 628 
204 1 Y 1 A GLN 641 ? E GLN 629 
205 1 Y 1 A ILE 642 ? E ILE 630 
206 1 Y 1 A LEU 643 ? E LEU 631 
207 1 Y 1 A LEU 644 ? E LEU 632 
208 1 Y 1 A LYS 645 ? E LYS 633 
209 1 Y 1 A SER 646 ? E SER 634 
210 1 Y 1 A LYS 647 ? E LYS 635 
211 1 Y 1 A LEU 648 ? E LEU 636 
212 1 Y 1 A LEU 649 ? E LEU 637 
213 1 Y 1 A VAL 650 ? E VAL 638 
214 1 Y 1 A LEU 651 ? E LEU 639 
215 1 Y 1 A GLU 652 ? E GLU 640 
216 1 Y 1 A ASP 653 ? E ASP 641 
217 1 Y 1 A GLU 654 ? E GLU 642 
218 1 Y 1 A ASN 655 ? E ASN 643 
219 1 Y 1 A ALA 656 ? E ALA 644 
220 1 Y 1 A ASN 657 ? E ASN 645 
221 1 Y 1 A VAL 658 ? E VAL 646 
222 1 Y 1 A ASP 659 ? E ASP 647 
223 1 Y 1 A GLU 660 ? E GLU 648 
224 1 Y 1 A VAL 661 ? E VAL 649 
225 1 Y 1 A GLU 662 ? E GLU 650 
226 1 Y 1 A LEU 663 ? E LEU 651 
227 1 Y 1 A LYS 664 ? E LYS 652 
228 1 Y 1 A PRO 665 ? E PRO 653 
229 1 Y 1 A ASP 666 ? E ASP 654 
230 1 Y 1 A THR 667 ? E THR 655 
231 1 Y 1 A LEU 668 ? E LEU 656 
232 1 Y 1 A ILE 669 ? E ILE 657 
233 1 Y 1 A LYS 670 ? E LYS 658 
234 1 Y 1 A LEU 671 ? E LEU 659 
235 1 Y 1 A TYR 672 ? E TYR 660 
236 1 Y 1 A LEU 673 ? E LEU 661 
237 1 Y 1 A GLY 674 ? E GLY 662 
238 1 Y 1 A TYR 675 ? E TYR 663 
239 1 Y 1 A LYS 676 ? E LYS 664 
240 1 Y 1 A ASN 677 ? E ASN 665 
241 1 Y 1 A LYS 678 ? E LYS 666 
242 1 Y 1 A LYS 679 ? E LYS 667 
243 1 Y 1 A LEU 680 ? E LEU 668 
244 1 Y 1 A ARG 681 ? E ARG 669 
245 1 Y 1 A VAL 682 ? E VAL 670 
246 1 Y 1 A ASN 683 ? E ASN 671 
247 1 Y 1 A ILE 684 ? E ILE 672 
248 1 Y 1 A ASN 685 ? E ASN 673 
249 1 Y 1 A VAL 686 ? E VAL 674 
250 1 Y 1 A PRO 687 ? E PRO 675 
251 1 Y 1 A MET 688 ? E MET 676 
252 1 Y 1 A LYS 689 ? E LYS 677 
253 1 Y 1 A THR 690 ? E THR 678 
254 1 Y 1 A GLU 691 ? E GLU 679 
255 1 Y 1 A GLN 692 ? E GLN 680 
256 1 Y 1 A LYS 693 ? E LYS 681 
257 1 Y 1 A GLN 694 ? E GLN 682 
258 1 Y 1 A GLU 695 ? E GLU 683 
259 1 Y 1 A GLN 696 ? E GLN 684 
260 1 Y 1 A GLU 697 ? E GLU 685 
261 1 Y 1 A THR 698 ? E THR 686 
262 1 Y 1 A THR 699 ? E THR 687 
263 1 Y 1 A HIS 700 ? E HIS 688 
264 1 Y 1 A LYS 701 ? E LYS 689 
265 1 Y 1 A ASN 702 ? E ASN 690 
266 1 Y 1 A ILE 703 ? E ILE 691 
267 1 Y 1 A GLU 704 ? E GLU 692 
268 1 Y 1 A GLU 705 ? E GLU 693 
269 1 Y 1 A ASP 706 ? E ASP 694 
270 1 Y 1 A ARG 707 ? E ARG 695 
271 1 Y 1 A LYS 708 ? E LYS 696 
272 1 Y 1 A LEU 709 ? E LEU 697 
273 1 Y 1 A LEU 710 ? E LEU 698 
274 1 Y 1 A ILE 711 ? E ILE 699 
275 1 Y 1 A GLN 712 ? E GLN 700 
276 1 Y 1 A ALA 713 ? E ALA 701 
277 1 Y 1 A ALA 714 ? E ALA 702 
278 1 Y 1 A ILE 715 ? E ILE 703 
279 1 Y 1 A VAL 716 ? E VAL 704 
280 1 Y 1 A ARG 717 ? E ARG 705 
281 1 Y 1 A ILE 718 ? E ILE 706 
282 1 Y 1 A MET 719 ? E MET 707 
283 1 Y 1 A LYS 720 ? E LYS 708 
284 1 Y 1 A MET 721 ? E MET 709 
285 1 Y 1 A ARG 722 ? E ARG 710 
286 1 Y 1 A LYS 723 ? E LYS 711 
287 1 Y 1 A VAL 724 ? E VAL 712 
288 1 Y 1 A LEU 725 ? E LEU 713 
289 1 Y 1 A LYS 726 ? E LYS 714 
290 1 Y 1 A HIS 727 ? E HIS 715 
291 1 Y 1 A GLN 728 ? E GLN 716 
292 1 Y 1 A GLN 729 ? E GLN 717 
293 1 Y 1 A LEU 730 ? E LEU 718 
294 1 Y 1 A LEU 731 ? E LEU 719 
295 1 Y 1 A GLY 732 ? E GLY 720 
296 1 Y 1 A GLU 733 ? E GLU 721 
297 1 Y 1 A VAL 734 ? E VAL 722 
298 1 Y 1 A LEU 735 ? E LEU 723 
299 1 Y 1 A THR 736 ? E THR 724 
300 1 Y 1 A GLN 737 ? E GLN 725 
301 1 Y 1 A LEU 738 ? E LEU 726 
302 1 Y 1 A SER 739 ? E SER 727 
303 1 Y 1 A SER 740 ? E SER 728 
304 1 Y 1 A ARG 741 ? E ARG 729 
305 1 Y 1 A PHE 742 ? E PHE 730 
306 1 Y 1 A LYS 743 ? E LYS 731 
307 1 Y 1 A PRO 744 ? E PRO 732 
308 1 Y 1 A ARG 745 ? E ARG 733 
309 1 Y 1 A VAL 746 ? E VAL 734 
310 1 Y 1 A PRO 747 ? E PRO 735 
311 1 Y 1 A VAL 748 ? E VAL 736 
312 1 Y 1 A ILE 749 ? E ILE 737 
313 1 Y 1 A LYS 750 ? E LYS 738 
314 1 Y 1 A LYS 751 ? E LYS 739 
315 1 Y 1 A CYS 752 ? E CYS 740 
316 1 Y 1 A ILE 753 ? E ILE 741 
317 1 Y 1 A ASP 754 ? E ASP 742 
318 1 Y 1 A ILE 755 ? E ILE 743 
319 1 Y 1 A LEU 756 ? E LEU 744 
320 1 Y 1 A ILE 757 ? E ILE 745 
321 1 Y 1 A GLU 758 ? E GLU 746 
322 1 Y 1 A LYS 759 ? E LYS 747 
323 1 Y 1 A GLU 760 ? E GLU 748 
324 1 Y 1 A TYR 761 ? E TYR 749 
325 1 Y 1 A LEU 762 ? E LEU 750 
326 1 Y 1 A GLU 763 ? E GLU 751 
327 1 Y 1 A ARG 764 ? E ARG 752 
328 1 Y 1 A VAL 765 ? E VAL 753 
329 1 Y 1 A ASP 766 ? E ASP 754 
330 1 Y 1 A GLY 767 ? E GLY 755 
331 1 Y 1 A GLU 768 ? E GLU 756 
332 1 Y 1 A LYS 769 ? E LYS 757 
333 1 Y 1 A ASP 770 ? E ASP 758 
334 1 Y 1 A THR 771 ? E THR 759 
335 1 Y 1 A TYR 772 ? E TYR 760 
336 1 Y 1 A SER 773 ? E SER 761 
337 1 Y 1 A TYR 774 ? E TYR 762 
338 1 Y 1 A LEU 775 ? E LEU 763 
339 1 Y 1 A ALA 776 ? E ALA 764 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-09-20 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8UA6 
_em_admin.last_update        2025-01-08 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'Cryo-EM Structure of SCF-FBOX22-BACH1BTB' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7111 
_em_entity_assembly_recombinant.organism             'Trichoplusia ni' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         59 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?         ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 SerialEM  ? 
MASKING                         ? 3  ? ? ? ?         ? 
'CTF CORRECTION'                ? 4  1 ? ? CTFFIND   ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ? 
'MODEL FITTING'                 ? 7  ? ? ? ?         ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ?         ? 
OTHER                           ? 9  ? ? ? ?         ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? cryoSPARC ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? cryoSPARC ? 
CLASSIFICATION                  ? 12 1 ? ? cryoSPARC ? 
RECONSTRUCTION                  ? 13 1 ? ? ?         ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?         ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Howard Hughes Medical Institute (HHMI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8UA6 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ASP A 1 16  ? 184.816 170.140 227.799 1.00 123.46 ? 16  ASP C N   1 
ATOM 2    C CA  . ASP A 1 16  ? 185.710 171.292 227.887 1.00 123.46 ? 16  ASP C CA  1 
ATOM 3    C C   . ASP A 1 16  ? 186.062 171.893 226.515 1.00 123.46 ? 16  ASP C C   1 
ATOM 4    O O   . ASP A 1 16  ? 186.083 173.117 226.379 1.00 123.46 ? 16  ASP C O   1 
ATOM 5    C CB  . ASP A 1 16  ? 186.991 170.918 228.644 1.00 123.46 ? 16  ASP C CB  1 
ATOM 6    C CG  . ASP A 1 16  ? 186.711 170.126 229.906 1.00 123.46 ? 16  ASP C CG  1 
ATOM 7    O OD1 . ASP A 1 16  ? 186.313 170.740 230.919 1.00 123.46 ? 16  ASP C OD1 1 
ATOM 8    O OD2 . ASP A 1 16  ? 186.887 168.890 229.885 1.00 123.46 ? 16  ASP C OD2 1 
ATOM 9    N N   . PRO A 1 17  ? 186.348 171.051 225.492 1.00 116.62 ? 17  PRO C N   1 
ATOM 10   C CA  . PRO A 1 17  ? 186.566 171.608 224.148 1.00 116.62 ? 17  PRO C CA  1 
ATOM 11   C C   . PRO A 1 17  ? 185.358 172.371 223.626 1.00 116.62 ? 17  PRO C C   1 
ATOM 12   O O   . PRO A 1 17  ? 184.275 172.327 224.217 1.00 116.62 ? 17  PRO C O   1 
ATOM 13   C CB  . PRO A 1 17  ? 186.858 170.367 223.290 1.00 116.62 ? 17  PRO C CB  1 
ATOM 14   C CG  . PRO A 1 17  ? 186.488 169.192 224.141 1.00 116.62 ? 17  PRO C CG  1 
ATOM 15   C CD  . PRO A 1 17  ? 186.744 169.633 225.532 1.00 116.62 ? 17  PRO C CD  1 
ATOM 16   N N   . ARG A 1 18  ? 185.539 173.071 222.507 1.00 103.52 ? 18  ARG C N   1 
ATOM 17   C CA  . ARG A 1 18  ? 184.527 173.993 222.000 1.00 103.52 ? 18  ARG C CA  1 
ATOM 18   C C   . ARG A 1 18  ? 183.245 173.289 221.563 1.00 103.52 ? 18  ARG C C   1 
ATOM 19   O O   . ARG A 1 18  ? 182.146 173.793 221.812 1.00 103.52 ? 18  ARG C O   1 
ATOM 20   C CB  . ARG A 1 18  ? 185.105 174.824 220.850 1.00 103.52 ? 18  ARG C CB  1 
ATOM 21   C CG  . ARG A 1 18  ? 185.019 176.322 221.090 1.00 103.52 ? 18  ARG C CG  1 
ATOM 22   C CD  . ARG A 1 18  ? 185.981 177.087 220.202 1.00 103.52 ? 18  ARG C CD  1 
ATOM 23   N NE  . ARG A 1 18  ? 187.369 176.868 220.589 1.00 103.52 ? 18  ARG C NE  1 
ATOM 24   C CZ  . ARG A 1 18  ? 187.937 177.372 221.676 1.00 103.52 ? 18  ARG C CZ  1 
ATOM 25   N NH1 . ARG A 1 18  ? 187.267 178.152 222.509 1.00 103.52 ? 18  ARG C NH1 1 
ATOM 26   N NH2 . ARG A 1 18  ? 189.212 177.094 221.930 1.00 103.52 ? 18  ARG C NH2 1 
ATOM 27   N N   . SER A 1 19  ? 183.358 172.128 220.914 1.00 103.02 ? 19  SER C N   1 
ATOM 28   C CA  . SER A 1 19  ? 182.160 171.544 220.319 1.00 103.02 ? 19  SER C CA  1 
ATOM 29   C C   . SER A 1 19  ? 181.282 170.873 221.366 1.00 103.02 ? 19  SER C C   1 
ATOM 30   O O   . SER A 1 19  ? 180.902 169.707 221.219 1.00 103.02 ? 19  SER C O   1 
ATOM 31   C CB  . SER A 1 19  ? 182.512 170.533 219.229 1.00 103.02 ? 19  SER C CB  1 
ATOM 32   O OG  . SER A 1 19  ? 183.614 169.743 219.605 1.00 103.02 ? 19  SER C OG  1 
ATOM 33   N N   . THR A 1 20  ? 180.955 171.608 222.422 1.00 104.26 ? 20  THR C N   1 
ATOM 34   C CA  . THR A 1 20  ? 179.771 171.330 223.217 1.00 104.26 ? 20  THR C CA  1 
ATOM 35   C C   . THR A 1 20  ? 178.733 172.310 222.702 1.00 104.26 ? 20  THR C C   1 
ATOM 36   O O   . THR A 1 20  ? 177.524 172.070 222.768 1.00 104.26 ? 20  THR C O   1 
ATOM 37   C CB  . THR A 1 20  ? 180.034 171.518 224.711 1.00 104.26 ? 20  THR C CB  1 
ATOM 38   O OG1 . THR A 1 20  ? 180.780 172.725 224.916 1.00 104.26 ? 20  THR C OG1 1 
ATOM 39   C CG2 . THR A 1 20  ? 180.828 170.347 225.262 1.00 104.26 ? 20  THR C CG2 1 
ATOM 40   N N   . PHE A 1 21  ? 179.237 173.430 222.186 1.00 97.34  ? 21  PHE C N   1 
ATOM 41   C CA  . PHE A 1 21  ? 178.470 174.426 221.454 1.00 97.34  ? 21  PHE C CA  1 
ATOM 42   C C   . PHE A 1 21  ? 178.307 174.016 219.996 1.00 97.34  ? 21  PHE C C   1 
ATOM 43   O O   . PHE A 1 21  ? 177.185 173.890 219.497 1.00 97.34  ? 21  PHE C O   1 
ATOM 44   C CB  . PHE A 1 21  ? 179.170 175.784 221.549 1.00 97.34  ? 21  PHE C CB  1 
ATOM 45   C CG  . PHE A 1 21  ? 178.454 176.892 220.838 1.00 97.34  ? 21  PHE C CG  1 
ATOM 46   C CD1 . PHE A 1 21  ? 177.384 177.537 221.432 1.00 97.34  ? 21  PHE C CD1 1 
ATOM 47   C CD2 . PHE A 1 21  ? 178.858 177.296 219.577 1.00 97.34  ? 21  PHE C CD2 1 
ATOM 48   C CE1 . PHE A 1 21  ? 176.725 178.559 220.778 1.00 97.34  ? 21  PHE C CE1 1 
ATOM 49   C CE2 . PHE A 1 21  ? 178.205 178.317 218.918 1.00 97.34  ? 21  PHE C CE2 1 
ATOM 50   C CZ  . PHE A 1 21  ? 177.136 178.950 219.520 1.00 97.34  ? 21  PHE C CZ  1 
ATOM 51   N N   . VAL A 1 22  ? 179.431 173.799 219.314 1.00 89.80  ? 22  VAL C N   1 
ATOM 52   C CA  . VAL A 1 22  ? 179.467 173.641 217.864 1.00 89.80  ? 22  VAL C CA  1 
ATOM 53   C C   . VAL A 1 22  ? 178.769 172.365 217.413 1.00 89.80  ? 22  VAL C C   1 
ATOM 54   O O   . VAL A 1 22  ? 177.931 172.393 216.505 1.00 89.80  ? 22  VAL C O   1 
ATOM 55   C CB  . VAL A 1 22  ? 180.919 173.660 217.357 1.00 89.80  ? 22  VAL C CB  1 
ATOM 56   C CG1 . VAL A 1 22  ? 180.974 173.283 215.886 1.00 89.80  ? 22  VAL C CG1 1 
ATOM 57   C CG2 . VAL A 1 22  ? 181.537 175.022 217.595 1.00 89.80  ? 22  VAL C CG2 1 
ATOM 58   N N   . LEU A 1 23  ? 179.099 171.241 218.044 1.00 86.84  ? 23  LEU C N   1 
ATOM 59   C CA  . LEU A 1 23  ? 178.659 169.951 217.530 1.00 86.84  ? 23  LEU C CA  1 
ATOM 60   C C   . LEU A 1 23  ? 177.236 169.682 218.010 1.00 86.84  ? 23  LEU C C   1 
ATOM 61   O O   . LEU A 1 23  ? 176.625 168.671 217.652 1.00 86.84  ? 23  LEU C O   1 
ATOM 62   C CB  . LEU A 1 23  ? 179.624 168.848 217.979 1.00 86.84  ? 23  LEU C CB  1 
ATOM 63   C CG  . LEU A 1 23  ? 179.469 167.398 217.510 1.00 86.84  ? 23  LEU C CG  1 
ATOM 64   C CD1 . LEU A 1 23  ? 178.867 167.340 216.114 1.00 86.84  ? 23  LEU C CD1 1 
ATOM 65   C CD2 . LEU A 1 23  ? 180.801 166.668 217.548 1.00 86.84  ? 23  LEU C CD2 1 
ATOM 66   N N   . SER A 1 24  ? 176.688 170.596 218.810 1.00 87.70  ? 24  SER C N   1 
ATOM 67   C CA  . SER A 1 24  ? 175.335 170.426 219.322 1.00 87.70  ? 24  SER C CA  1 
ATOM 68   C C   . SER A 1 24  ? 174.381 171.546 218.947 1.00 87.70  ? 24  SER C C   1 
ATOM 69   O O   . SER A 1 24  ? 173.177 171.389 219.169 1.00 87.70  ? 24  SER C O   1 
ATOM 70   C CB  . SER A 1 24  ? 175.356 170.295 220.851 1.00 87.70  ? 24  SER C CB  1 
ATOM 71   O OG  . SER A 1 24  ? 175.834 171.486 221.450 1.00 87.70  ? 24  SER C OG  1 
ATOM 72   N N   . ASN A 1 25  ? 174.858 172.667 218.409 1.00 87.89  ? 25  ASN C N   1 
ATOM 73   C CA  . ASN A 1 25  ? 173.972 173.758 218.025 1.00 87.89  ? 25  ASN C CA  1 
ATOM 74   C C   . ASN A 1 25  ? 174.096 174.081 216.541 1.00 87.89  ? 25  ASN C C   1 
ATOM 75   O O   . ASN A 1 25  ? 173.084 174.248 215.853 1.00 87.89  ? 25  ASN C O   1 
ATOM 76   C CB  . ASN A 1 25  ? 174.259 175.000 218.869 1.00 87.89  ? 25  ASN C CB  1 
ATOM 77   C CG  . ASN A 1 25  ? 174.312 174.693 220.350 1.00 87.89  ? 25  ASN C CG  1 
ATOM 78   O OD1 . ASN A 1 25  ? 173.656 173.769 220.829 1.00 87.89  ? 25  ASN C OD1 1 
ATOM 79   N ND2 . ASN A 1 25  ? 175.097 175.468 221.086 1.00 87.89  ? 25  ASN C ND2 1 
ATOM 80   N N   . LEU A 1 26  ? 175.328 174.180 216.040 1.00 79.17  ? 26  LEU C N   1 
ATOM 81   C CA  . LEU A 1 26  ? 175.551 174.521 214.640 1.00 79.17  ? 26  LEU C CA  1 
ATOM 82   C C   . LEU A 1 26  ? 174.975 173.441 213.734 1.00 79.17  ? 26  LEU C C   1 
ATOM 83   O O   . LEU A 1 26  ? 175.514 172.333 213.657 1.00 79.17  ? 26  LEU C O   1 
ATOM 84   C CB  . LEU A 1 26  ? 177.043 174.710 214.366 1.00 79.17  ? 26  LEU C CB  1 
ATOM 85   C CG  . LEU A 1 26  ? 177.498 176.163 214.260 1.00 79.17  ? 26  LEU C CG  1 
ATOM 86   C CD1 . LEU A 1 26  ? 177.529 176.790 215.640 1.00 79.17  ? 26  LEU C CD1 1 
ATOM 87   C CD2 . LEU A 1 26  ? 178.860 176.259 213.600 1.00 79.17  ? 26  LEU C CD2 1 
ATOM 88   N N   . ALA A 1 27  ? 173.883 173.760 213.039 1.00 76.55  ? 27  ALA C N   1 
ATOM 89   C CA  . ALA A 1 27  ? 173.169 172.749 212.267 1.00 76.55  ? 27  ALA C CA  1 
ATOM 90   C C   . ALA A 1 27  ? 173.938 172.365 211.009 1.00 76.55  ? 27  ALA C C   1 
ATOM 91   O O   . ALA A 1 27  ? 173.965 171.194 210.614 1.00 76.55  ? 27  ALA C O   1 
ATOM 92   C CB  . ALA A 1 27  ? 171.770 173.254 211.915 1.00 76.55  ? 27  ALA C CB  1 
ATOM 93   N N   . GLU A 1 28  ? 174.572 173.342 210.363 1.00 77.98  ? 28  GLU C N   1 
ATOM 94   C CA  . GLU A 1 28  ? 175.210 173.094 209.076 1.00 77.98  ? 28  GLU C CA  1 
ATOM 95   C C   . GLU A 1 28  ? 176.455 172.227 209.212 1.00 77.98  ? 28  GLU C C   1 
ATOM 96   O O   . GLU A 1 28  ? 176.891 171.606 208.238 1.00 77.98  ? 28  GLU C O   1 
ATOM 97   C CB  . GLU A 1 28  ? 175.561 174.416 208.392 1.00 77.98  ? 28  GLU C CB  1 
ATOM 98   C CG  . GLU A 1 28  ? 175.754 174.291 206.891 1.00 77.98  ? 28  GLU C CG  1 
ATOM 99   C CD  . GLU A 1 28  ? 177.201 174.050 206.507 1.00 77.98  ? 28  GLU C CD  1 
ATOM 100  O OE1 . GLU A 1 28  ? 178.085 174.239 207.368 1.00 77.98  ? 28  GLU C OE1 1 
ATOM 101  O OE2 . GLU A 1 28  ? 177.455 173.666 205.346 1.00 77.98  ? 28  GLU C OE2 1 
ATOM 102  N N   . VAL A 1 29  ? 177.030 172.162 210.411 1.00 75.35  ? 29  VAL C N   1 
ATOM 103  C CA  . VAL A 1 29  ? 178.212 171.348 210.654 1.00 75.35  ? 29  VAL C CA  1 
ATOM 104  C C   . VAL A 1 29  ? 177.848 169.927 211.063 1.00 75.35  ? 29  VAL C C   1 
ATOM 105  O O   . VAL A 1 29  ? 178.642 169.007 210.873 1.00 75.35  ? 29  VAL C O   1 
ATOM 106  C CB  . VAL A 1 29  ? 179.133 172.004 211.701 1.00 75.35  ? 29  VAL C CB  1 
ATOM 107  C CG1 . VAL A 1 29  ? 180.458 171.270 211.785 1.00 75.35  ? 29  VAL C CG1 1 
ATOM 108  C CG2 . VAL A 1 29  ? 179.361 173.461 211.356 1.00 75.35  ? 29  VAL C CG2 1 
ATOM 109  N N   . VAL A 1 30  ? 176.643 169.722 211.588 1.00 76.50  ? 30  VAL C N   1 
ATOM 110  C CA  . VAL A 1 30  ? 176.193 168.386 211.954 1.00 76.50  ? 30  VAL C CA  1 
ATOM 111  C C   . VAL A 1 30  ? 175.613 167.739 210.702 1.00 76.50  ? 30  VAL C C   1 
ATOM 112  O O   . VAL A 1 30  ? 175.459 166.515 210.631 1.00 76.50  ? 30  VAL C O   1 
ATOM 113  C CB  . VAL A 1 30  ? 175.170 168.445 213.105 1.00 76.50  ? 30  VAL C CB  1 
ATOM 114  C CG1 . VAL A 1 30  ? 174.673 167.055 213.478 1.00 76.50  ? 30  VAL C CG1 1 
ATOM 115  C CG2 . VAL A 1 30  ? 175.778 169.131 214.313 1.00 76.50  ? 30  VAL C CG2 1 
ATOM 116  N N   . GLU A 1 31  ? 175.339 168.554 209.684 1.00 82.37  ? 31  GLU C N   1 
ATOM 117  C CA  . GLU A 1 31  ? 174.814 168.033 208.429 1.00 82.37  ? 31  GLU C CA  1 
ATOM 118  C C   . GLU A 1 31  ? 175.940 167.509 207.552 1.00 82.37  ? 31  GLU C C   1 
ATOM 119  O O   . GLU A 1 31  ? 175.833 166.412 206.996 1.00 82.37  ? 31  GLU C O   1 
ATOM 120  C CB  . GLU A 1 31  ? 174.015 169.102 207.682 1.00 82.37  ? 31  GLU C CB  1 
ATOM 121  C CG  . GLU A 1 31  ? 172.511 168.991 207.864 1.00 82.37  ? 31  GLU C CG  1 
ATOM 122  C CD  . GLU A 1 31  ? 171.735 169.779 206.826 1.00 82.37  ? 31  GLU C CD  1 
ATOM 123  O OE1 . GLU A 1 31  ? 172.113 169.730 205.636 1.00 82.37  ? 31  GLU C OE1 1 
ATOM 124  O OE2 . GLU A 1 31  ? 170.745 170.443 207.198 1.00 82.37  ? 31  GLU C OE2 1 
ATOM 125  N N   . ARG A 1 32  ? 177.026 168.270 207.418 1.00 80.26  ? 32  ARG C N   1 
ATOM 126  C CA  . ARG A 1 32  ? 178.153 167.769 206.643 1.00 80.26  ? 32  ARG C CA  1 
ATOM 127  C C   . ARG A 1 32  ? 179.090 166.957 207.524 1.00 80.26  ? 32  ARG C C   1 
ATOM 128  O O   . ARG A 1 32  ? 180.310 167.133 207.472 1.00 80.26  ? 32  ARG C O   1 
ATOM 129  C CB  . ARG A 1 32  ? 178.921 168.921 205.995 1.00 80.26  ? 32  ARG C CB  1 
ATOM 130  C CG  . ARG A 1 32  ? 179.372 168.642 204.574 1.00 80.26  ? 32  ARG C CG  1 
ATOM 131  C CD  . ARG A 1 32  ? 180.517 169.554 204.175 1.00 80.26  ? 32  ARG C CD  1 
ATOM 132  N NE  . ARG A 1 32  ? 180.195 170.960 204.388 1.00 80.26  ? 32  ARG C NE  1 
ATOM 133  C CZ  . ARG A 1 32  ? 179.607 171.737 203.490 1.00 80.26  ? 32  ARG C CZ  1 
ATOM 134  N NH1 . ARG A 1 32  ? 179.254 171.275 202.302 1.00 80.26  ? 32  ARG C NH1 1 
ATOM 135  N NH2 . ARG A 1 32  ? 179.367 173.010 203.791 1.00 80.26  ? 32  ARG C NH2 1 
ATOM 136  N N   . VAL A 1 33  ? 178.526 166.064 208.332 1.00 78.98  ? 33  VAL C N   1 
ATOM 137  C CA  . VAL A 1 33  ? 179.289 165.047 209.045 1.00 78.98  ? 33  VAL C CA  1 
ATOM 138  C C   . VAL A 1 33  ? 178.603 163.714 208.796 1.00 78.98  ? 33  VAL C C   1 
ATOM 139  O O   . VAL A 1 33  ? 179.239 162.733 208.395 1.00 78.98  ? 33  VAL C O   1 
ATOM 140  C CB  . VAL A 1 33  ? 179.399 165.355 210.548 1.00 78.98  ? 33  VAL C CB  1 
ATOM 141  C CG1 . VAL A 1 33  ? 179.604 164.075 211.339 1.00 78.98  ? 33  VAL C CG1 1 
ATOM 142  C CG2 . VAL A 1 33  ? 180.539 166.323 210.801 1.00 78.98  ? 33  VAL C CG2 1 
ATOM 143  N N   . LEU A 1 34  ? 177.291 163.684 209.025 1.00 78.48  ? 34  LEU C N   1 
ATOM 144  C CA  . LEU A 1 34  ? 176.508 162.458 208.963 1.00 78.48  ? 34  LEU C CA  1 
ATOM 145  C C   . LEU A 1 34  ? 176.325 161.979 207.530 1.00 78.48  ? 34  LEU C C   1 
ATOM 146  O O   . LEU A 1 34  ? 175.823 160.874 207.300 1.00 78.48  ? 34  LEU C O   1 
ATOM 147  C CB  . LEU A 1 34  ? 175.153 162.677 209.631 1.00 78.48  ? 34  LEU C CB  1 
ATOM 148  C CG  . LEU A 1 34  ? 175.270 163.050 211.107 1.00 78.48  ? 34  LEU C CG  1 
ATOM 149  C CD1 . LEU A 1 34  ? 173.904 163.117 211.753 1.00 78.48  ? 34  LEU C CD1 1 
ATOM 150  C CD2 . LEU A 1 34  ? 176.161 162.049 211.822 1.00 78.48  ? 34  LEU C CD2 1 
ATOM 151  N N   . THR A 1 35  ? 176.734 162.792 206.562 1.00 81.64  ? 35  THR C N   1 
ATOM 152  C CA  . THR A 1 35  ? 176.793 162.345 205.178 1.00 81.64  ? 35  THR C CA  1 
ATOM 153  C C   . THR A 1 35  ? 177.967 161.414 204.934 1.00 81.64  ? 35  THR C C   1 
ATOM 154  O O   . THR A 1 35  ? 177.907 160.565 204.040 1.00 81.64  ? 35  THR C O   1 
ATOM 155  C CB  . THR A 1 35  ? 176.899 163.543 204.231 1.00 81.64  ? 35  THR C CB  1 
ATOM 156  O OG1 . THR A 1 35  ? 177.944 164.414 204.679 1.00 81.64  ? 35  THR C OG1 1 
ATOM 157  C CG2 . THR A 1 35  ? 175.591 164.314 204.197 1.00 81.64  ? 35  THR C CG2 1 
ATOM 158  N N   . PHE A 1 36  ? 179.032 161.555 205.723 1.00 83.96  ? 36  PHE C N   1 
ATOM 159  C CA  . PHE A 1 36  ? 180.254 160.772 205.550 1.00 83.96  ? 36  PHE C CA  1 
ATOM 160  C C   . PHE A 1 36  ? 180.207 159.596 206.520 1.00 83.96  ? 36  PHE C C   1 
ATOM 161  O O   . PHE A 1 36  ? 181.091 159.390 207.354 1.00 83.96  ? 36  PHE C O   1 
ATOM 162  C CB  . PHE A 1 36  ? 181.486 161.641 205.775 1.00 83.96  ? 36  PHE C CB  1 
ATOM 163  C CG  . PHE A 1 36  ? 181.678 162.720 204.742 1.00 83.96  ? 36  PHE C CG  1 
ATOM 164  C CD1 . PHE A 1 36  ? 180.694 163.006 203.810 1.00 83.96  ? 36  PHE C CD1 1 
ATOM 165  C CD2 . PHE A 1 36  ? 182.854 163.442 204.700 1.00 83.96  ? 36  PHE C CD2 1 
ATOM 166  C CE1 . PHE A 1 36  ? 180.874 163.993 202.868 1.00 83.96  ? 36  PHE C CE1 1 
ATOM 167  C CE2 . PHE A 1 36  ? 183.041 164.431 203.759 1.00 83.96  ? 36  PHE C CE2 1 
ATOM 168  C CZ  . PHE A 1 36  ? 182.048 164.706 202.842 1.00 83.96  ? 36  PHE C CZ  1 
ATOM 169  N N   . LEU A 1 37  ? 179.140 158.811 206.403 1.00 80.33  ? 37  LEU C N   1 
ATOM 170  C CA  . LEU A 1 37  ? 178.927 157.665 207.273 1.00 80.33  ? 37  LEU C CA  1 
ATOM 171  C C   . LEU A 1 37  ? 178.213 156.590 206.475 1.00 80.33  ? 37  LEU C C   1 
ATOM 172  O O   . LEU A 1 37  ? 177.441 156.913 205.566 1.00 80.33  ? 37  LEU C O   1 
ATOM 173  C CB  . LEU A 1 37  ? 178.097 158.050 208.507 1.00 80.33  ? 37  LEU C CB  1 
ATOM 174  C CG  . LEU A 1 37  ? 178.833 158.499 209.770 1.00 80.33  ? 37  LEU C CG  1 
ATOM 175  C CD1 . LEU A 1 37  ? 177.879 158.530 210.953 1.00 80.33  ? 37  LEU C CD1 1 
ATOM 176  C CD2 . LEU A 1 37  ? 180.025 157.603 210.063 1.00 80.33  ? 37  LEU C CD2 1 
ATOM 177  N N   . PRO A 1 38  ? 178.445 155.312 206.781 1.00 84.15  ? 38  PRO C N   1 
ATOM 178  C CA  . PRO A 1 38  ? 177.639 154.253 206.163 1.00 84.15  ? 38  PRO C CA  1 
ATOM 179  C C   . PRO A 1 38  ? 176.193 154.375 206.622 1.00 84.15  ? 38  PRO C C   1 
ATOM 180  O O   . PRO A 1 38  ? 175.918 154.909 207.698 1.00 84.15  ? 38  PRO C O   1 
ATOM 181  C CB  . PRO A 1 38  ? 178.289 152.963 206.676 1.00 84.15  ? 38  PRO C CB  1 
ATOM 182  C CG  . PRO A 1 38  ? 178.919 153.358 207.965 1.00 84.15  ? 38  PRO C CG  1 
ATOM 183  C CD  . PRO A 1 38  ? 179.383 154.778 207.782 1.00 84.15  ? 38  PRO C CD  1 
ATOM 184  N N   . ALA A 1 39  ? 175.272 153.890 205.790 1.00 80.90  ? 39  ALA C N   1 
ATOM 185  C CA  . ALA A 1 39  ? 173.843 154.026 206.048 1.00 80.90  ? 39  ALA C CA  1 
ATOM 186  C C   . ALA A 1 39  ? 173.479 153.540 207.442 1.00 80.90  ? 39  ALA C C   1 
ATOM 187  O O   . ALA A 1 39  ? 172.658 154.157 208.126 1.00 80.90  ? 39  ALA C O   1 
ATOM 188  C CB  . ALA A 1 39  ? 173.032 153.255 205.008 1.00 80.90  ? 39  ALA C CB  1 
ATOM 189  N N   . LYS A 1 40  ? 174.100 152.446 207.879 1.00 92.58  ? 40  LYS C N   1 
ATOM 190  C CA  . LYS A 1 40  ? 173.725 151.837 209.148 1.00 92.58  ? 40  LYS C CA  1 
ATOM 191  C C   . LYS A 1 40  ? 174.165 152.701 210.321 1.00 92.58  ? 40  LYS C C   1 
ATOM 192  O O   . LYS A 1 40  ? 173.451 152.825 211.321 1.00 92.58  ? 40  LYS C O   1 
ATOM 193  C CB  . LYS A 1 40  ? 174.335 150.440 209.240 1.00 92.58  ? 40  LYS C CB  1 
ATOM 194  C CG  . LYS A 1 40  ? 173.753 149.592 210.340 1.00 92.58  ? 40  LYS C CG  1 
ATOM 195  C CD  . LYS A 1 40  ? 172.457 149.013 209.820 1.00 92.58  ? 40  LYS C CD  1 
ATOM 196  C CE  . LYS A 1 40  ? 172.731 148.132 208.616 1.00 92.58  ? 40  LYS C CE  1 
ATOM 197  N NZ  . LYS A 1 40  ? 171.641 148.219 207.607 1.00 92.58  ? 40  LYS C NZ  1 
ATOM 198  N N   . ALA A 1 41  ? 175.345 153.309 210.210 1.00 91.36  ? 41  ALA C N   1 
ATOM 199  C CA  . ALA A 1 41  ? 175.794 154.268 211.209 1.00 91.36  ? 41  ALA C CA  1 
ATOM 200  C C   . ALA A 1 41  ? 174.933 155.519 211.242 1.00 91.36  ? 41  ALA C C   1 
ATOM 201  O O   . ALA A 1 41  ? 174.772 156.112 212.313 1.00 91.36  ? 41  ALA C O   1 
ATOM 202  C CB  . ALA A 1 41  ? 177.249 154.658 210.952 1.00 91.36  ? 41  ALA C CB  1 
ATOM 203  N N   . LEU A 1 42  ? 174.372 155.923 210.103 1.00 85.90  ? 42  LEU C N   1 
ATOM 204  C CA  . LEU A 1 42  ? 173.497 157.085 210.039 1.00 85.90  ? 42  LEU C CA  1 
ATOM 205  C C   . LEU A 1 42  ? 172.244 156.918 210.882 1.00 85.90  ? 42  LEU C C   1 
ATOM 206  O O   . LEU A 1 42  ? 171.698 157.920 211.352 1.00 85.90  ? 42  LEU C O   1 
ATOM 207  C CB  . LEU A 1 42  ? 173.112 157.358 208.584 1.00 85.90  ? 42  LEU C CB  1 
ATOM 208  C CG  . LEU A 1 42  ? 172.458 158.695 208.235 1.00 85.90  ? 42  LEU C CG  1 
ATOM 209  C CD1 . LEU A 1 42  ? 173.005 159.816 209.100 1.00 85.90  ? 42  LEU C CD1 1 
ATOM 210  C CD2 . LEU A 1 42  ? 172.660 159.003 206.762 1.00 85.90  ? 42  LEU C CD2 1 
ATOM 211  N N   . LEU A 1 43  ? 171.780 155.687 211.088 1.00 90.56  ? 43  LEU C N   1 
ATOM 212  C CA  . LEU A 1 43  ? 170.653 155.418 211.969 1.00 90.56  ? 43  LEU C CA  1 
ATOM 213  C C   . LEU A 1 43  ? 171.091 155.088 213.390 1.00 90.56  ? 43  LEU C C   1 
ATOM 214  O O   . LEU A 1 43  ? 170.238 154.896 214.263 1.00 90.56  ? 43  LEU C O   1 
ATOM 215  C CB  . LEU A 1 43  ? 169.790 154.287 211.405 1.00 90.56  ? 43  LEU C CB  1 
ATOM 216  C CG  . LEU A 1 43  ? 169.186 154.491 210.013 1.00 90.56  ? 43  LEU C CG  1 
ATOM 217  C CD1 . LEU A 1 43  ? 169.768 153.513 209.011 1.00 90.56  ? 43  LEU C CD1 1 
ATOM 218  C CD2 . LEU A 1 43  ? 167.673 154.376 210.061 1.00 90.56  ? 43  LEU C CD2 1 
ATOM 219  N N   . ARG A 1 44  ? 172.397 155.018 213.645 1.00 96.13  ? 44  ARG C N   1 
ATOM 220  C CA  . ARG A 1 44  ? 172.896 154.819 215.000 1.00 96.13  ? 44  ARG C CA  1 
ATOM 221  C C   . ARG A 1 44  ? 173.002 156.153 215.726 1.00 96.13  ? 44  ARG C C   1 
ATOM 222  O O   . ARG A 1 44  ? 172.546 156.285 216.866 1.00 96.13  ? 44  ARG C O   1 
ATOM 223  C CB  . ARG A 1 44  ? 174.256 154.116 214.984 1.00 96.13  ? 44  ARG C CB  1 
ATOM 224  C CG  . ARG A 1 44  ? 174.293 152.828 215.792 1.00 96.13  ? 44  ARG C CG  1 
ATOM 225  C CD  . ARG A 1 44  ? 175.666 152.178 215.743 1.00 96.13  ? 44  ARG C CD  1 
ATOM 226  N NE  . ARG A 1 44  ? 176.031 151.771 214.392 1.00 96.13  ? 44  ARG C NE  1 
ATOM 227  C CZ  . ARG A 1 44  ? 177.262 151.460 214.011 1.00 96.13  ? 44  ARG C CZ  1 
ATOM 228  N NH1 . ARG A 1 44  ? 178.276 151.486 214.860 1.00 96.13  ? 44  ARG C NH1 1 
ATOM 229  N NH2 . ARG A 1 44  ? 177.481 151.112 212.746 1.00 96.13  ? 44  ARG C NH2 1 
ATOM 230  N N   . VAL A 1 45  ? 173.593 157.149 215.067 1.00 93.58  ? 45  VAL C N   1 
ATOM 231  C CA  . VAL A 1 45  ? 173.807 158.460 215.672 1.00 93.58  ? 45  VAL C CA  1 
ATOM 232  C C   . VAL A 1 45  ? 172.504 159.246 215.684 1.00 93.58  ? 45  VAL C C   1 
ATOM 233  O O   . VAL A 1 45  ? 172.449 160.366 216.205 1.00 93.58  ? 45  VAL C O   1 
ATOM 234  C CB  . VAL A 1 45  ? 174.908 159.243 214.935 1.00 93.58  ? 45  VAL C CB  1 
ATOM 235  C CG1 . VAL A 1 45  ? 176.281 158.821 215.430 1.00 93.58  ? 45  VAL C CG1 1 
ATOM 236  C CG2 . VAL A 1 45  ? 174.782 159.054 213.438 1.00 93.58  ? 45  VAL C CG2 1 
ATOM 237  N N   . ALA A 1 46  ? 171.450 158.672 215.104 1.00 97.38  ? 46  ALA C N   1 
ATOM 238  C CA  . ALA A 1 46  ? 170.135 159.301 215.099 1.00 97.38  ? 46  ALA C CA  1 
ATOM 239  C C   . ALA A 1 46  ? 169.614 159.475 216.519 1.00 97.38  ? 46  ALA C C   1 
ATOM 240  O O   . ALA A 1 46  ? 168.709 160.279 216.764 1.00 97.38  ? 46  ALA C O   1 
ATOM 241  C CB  . ALA A 1 46  ? 169.150 158.478 214.267 1.00 97.38  ? 46  ALA C CB  1 
ATOM 242  N N   . CYS A 1 47  ? 170.180 158.722 217.460 1.00 109.64 ? 47  CYS C N   1 
ATOM 243  C CA  . CYS A 1 47  ? 169.853 158.844 218.873 1.00 109.64 ? 47  CYS C CA  1 
ATOM 244  C C   . CYS A 1 47  ? 171.018 159.383 219.693 1.00 109.64 ? 47  CYS C C   1 
ATOM 245  O O   . CYS A 1 47  ? 171.289 158.866 220.781 1.00 109.64 ? 47  CYS C O   1 
ATOM 246  C CB  . CYS A 1 47  ? 169.397 157.494 219.429 1.00 109.64 ? 47  CYS C CB  1 
ATOM 247  S SG  . CYS A 1 47  ? 168.128 156.671 218.438 1.00 109.64 ? 47  CYS C SG  1 
ATOM 248  N N   . VAL A 1 48  ? 171.736 160.383 219.183 1.00 102.25 ? 48  VAL C N   1 
ATOM 249  C CA  . VAL A 1 48  ? 172.772 161.058 219.955 1.00 102.25 ? 48  VAL C CA  1 
ATOM 250  C C   . VAL A 1 48  ? 172.103 162.125 220.809 1.00 102.25 ? 48  VAL C C   1 
ATOM 251  O O   . VAL A 1 48  ? 172.205 162.108 222.041 1.00 102.25 ? 48  VAL C O   1 
ATOM 252  C CB  . VAL A 1 48  ? 173.854 161.663 219.041 1.00 102.25 ? 48  VAL C CB  1 
ATOM 253  C CG1 . VAL A 1 48  ? 174.660 162.715 219.789 1.00 102.25 ? 48  VAL C CG1 1 
ATOM 254  C CG2 . VAL A 1 48  ? 174.767 160.572 218.512 1.00 102.25 ? 48  VAL C CG2 1 
ATOM 255  N N   . CYS A 1 49  ? 171.411 163.058 220.158 1.00 103.87 ? 49  CYS C N   1 
ATOM 256  C CA  . CYS A 1 49  ? 170.611 164.057 220.854 1.00 103.87 ? 49  CYS C CA  1 
ATOM 257  C C   . CYS A 1 49  ? 169.426 164.449 219.982 1.00 103.87 ? 49  CYS C C   1 
ATOM 258  O O   . CYS A 1 49  ? 169.119 163.761 219.004 1.00 103.87 ? 49  CYS C O   1 
ATOM 259  C CB  . CYS A 1 49  ? 171.448 165.286 221.208 1.00 103.87 ? 49  CYS C CB  1 
ATOM 260  S SG  . CYS A 1 49  ? 171.927 166.295 219.795 1.00 103.87 ? 49  CYS C SG  1 
ATOM 261  N N   . ARG A 1 50  ? 168.753 165.547 220.322 1.00 99.86  ? 50  ARG C N   1 
ATOM 262  C CA  . ARG A 1 50  ? 167.587 165.986 219.572 1.00 99.86  ? 50  ARG C CA  1 
ATOM 263  C C   . ARG A 1 50  ? 167.913 166.672 218.254 1.00 99.86  ? 50  ARG C C   1 
ATOM 264  O O   . ARG A 1 50  ? 167.149 166.513 217.297 1.00 99.86  ? 50  ARG C O   1 
ATOM 265  C CB  . ARG A 1 50  ? 166.724 166.933 220.421 1.00 99.86  ? 50  ARG C CB  1 
ATOM 266  C CG  . ARG A 1 50  ? 165.236 166.795 220.156 1.00 99.86  ? 50  ARG C CG  1 
ATOM 267  C CD  . ARG A 1 50  ? 164.822 165.330 220.161 1.00 99.86  ? 50  ARG C CD  1 
ATOM 268  N NE  . ARG A 1 50  ? 164.797 164.771 221.507 1.00 99.86  ? 50  ARG C NE  1 
ATOM 269  C CZ  . ARG A 1 50  ? 165.145 163.527 221.808 1.00 99.86  ? 50  ARG C CZ  1 
ATOM 270  N NH1 . ARG A 1 50  ? 165.557 162.681 220.878 1.00 99.86  ? 50  ARG C NH1 1 
ATOM 271  N NH2 . ARG A 1 50  ? 165.081 163.123 223.073 1.00 99.86  ? 50  ARG C NH2 1 
ATOM 272  N N   . LEU A 1 51  ? 169.013 167.421 218.171 1.00 92.71  ? 51  LEU C N   1 
ATOM 273  C CA  . LEU A 1 51  ? 169.367 168.087 216.917 1.00 92.71  ? 51  LEU C CA  1 
ATOM 274  C C   . LEU A 1 51  ? 169.888 167.086 215.891 1.00 92.71  ? 51  LEU C C   1 
ATOM 275  O O   . LEU A 1 51  ? 169.661 167.237 214.687 1.00 92.71  ? 51  LEU C O   1 
ATOM 276  C CB  . LEU A 1 51  ? 170.396 169.192 217.175 1.00 92.71  ? 51  LEU C CB  1 
ATOM 277  C CG  . LEU A 1 51  ? 170.307 170.385 216.221 1.00 92.71  ? 51  LEU C CG  1 
ATOM 278  C CD1 . LEU A 1 51  ? 168.856 170.737 215.934 1.00 92.71  ? 51  LEU C CD1 1 
ATOM 279  C CD2 . LEU A 1 51  ? 171.049 171.587 216.779 1.00 92.71  ? 51  LEU C CD2 1 
ATOM 280  N N   . TRP A 1 52  ? 170.601 166.060 216.355 1.00 87.56  ? 52  TRP C N   1 
ATOM 281  C CA  . TRP A 1 52  ? 171.167 165.058 215.461 1.00 87.56  ? 52  TRP C CA  1 
ATOM 282  C C   . TRP A 1 52  ? 170.073 164.304 214.717 1.00 87.56  ? 52  TRP C C   1 
ATOM 283  O O   . TRP A 1 52  ? 170.266 163.900 213.566 1.00 87.56  ? 52  TRP C O   1 
ATOM 284  C CB  . TRP A 1 52  ? 172.046 164.080 216.238 1.00 87.56  ? 52  TRP C CB  1 
ATOM 285  C CG  . TRP A 1 52  ? 173.424 164.591 216.485 1.00 87.56  ? 52  TRP C CG  1 
ATOM 286  C CD1 . TRP A 1 52  ? 173.766 165.757 217.097 1.00 87.56  ? 52  TRP C CD1 1 
ATOM 287  C CD2 . TRP A 1 52  ? 174.652 163.955 216.118 1.00 87.56  ? 52  TRP C CD2 1 
ATOM 288  N NE1 . TRP A 1 52  ? 175.131 165.886 217.142 1.00 87.56  ? 52  TRP C NE1 1 
ATOM 289  C CE2 . TRP A 1 52  ? 175.698 164.792 216.545 1.00 87.56  ? 52  TRP C CE2 1 
ATOM 290  C CE3 . TRP A 1 52  ? 174.968 162.758 215.471 1.00 87.56  ? 52  TRP C CE3 1 
ATOM 291  C CZ2 . TRP A 1 52  ? 177.035 164.471 216.348 1.00 87.56  ? 52  TRP C CZ2 1 
ATOM 292  C CZ3 . TRP A 1 52  ? 176.298 162.443 215.276 1.00 87.56  ? 52  TRP C CZ3 1 
ATOM 293  C CH2 . TRP A 1 52  ? 177.314 163.297 215.710 1.00 87.56  ? 52  TRP C CH2 1 
ATOM 294  N N   . ARG A 1 53  ? 168.927 164.105 215.366 1.00 87.69  ? 53  ARG C N   1 
ATOM 295  C CA  . ARG A 1 53  ? 167.810 163.412 214.739 1.00 87.69  ? 53  ARG C CA  1 
ATOM 296  C C   . ARG A 1 53  ? 167.348 164.137 213.482 1.00 87.69  ? 53  ARG C C   1 
ATOM 297  O O   . ARG A 1 53  ? 167.165 163.515 212.431 1.00 87.69  ? 53  ARG C O   1 
ATOM 298  C CB  . ARG A 1 53  ? 166.641 163.279 215.712 1.00 87.69  ? 53  ARG C CB  1 
ATOM 299  C CG  . ARG A 1 53  ? 165.328 162.967 215.020 1.00 87.69  ? 53  ARG C CG  1 
ATOM 300  C CD  . ARG A 1 53  ? 164.396 162.190 215.918 1.00 87.69  ? 53  ARG C CD  1 
ATOM 301  N NE  . ARG A 1 53  ? 162.999 162.447 215.592 1.00 87.69  ? 53  ARG C NE  1 
ATOM 302  C CZ  . ARG A 1 53  ? 162.276 163.426 216.117 1.00 87.69  ? 53  ARG C CZ  1 
ATOM 303  N NH1 . ARG A 1 53  ? 162.786 164.263 217.006 1.00 87.69  ? 53  ARG C NH1 1 
ATOM 304  N NH2 . ARG A 1 53  ? 161.008 163.570 215.740 1.00 87.69  ? 53  ARG C NH2 1 
ATOM 305  N N   . GLU A 1 54  ? 167.161 165.451 213.584 1.00 91.02  ? 54  GLU C N   1 
ATOM 306  C CA  . GLU A 1 54  ? 166.724 166.247 212.446 1.00 91.02  ? 54  GLU C CA  1 
ATOM 307  C C   . GLU A 1 54  ? 167.755 166.168 211.331 1.00 91.02  ? 54  GLU C C   1 
ATOM 308  O O   . GLU A 1 54  ? 167.400 166.045 210.154 1.00 91.02  ? 54  GLU C O   1 
ATOM 309  C CB  . GLU A 1 54  ? 166.492 167.700 212.863 1.00 91.02  ? 54  GLU C CB  1 
ATOM 310  C CG  . GLU A 1 54  ? 165.321 167.891 213.811 1.00 91.02  ? 54  GLU C CG  1 
ATOM 311  C CD  . GLU A 1 54  ? 165.217 169.312 214.329 1.00 91.02  ? 54  GLU C CD  1 
ATOM 312  O OE1 . GLU A 1 54  ? 166.145 170.109 214.074 1.00 91.02  ? 54  GLU C OE1 1 
ATOM 313  O OE2 . GLU A 1 54  ? 164.210 169.632 214.994 1.00 91.02  ? 54  GLU C OE2 1 
ATOM 314  N N   . CYS A 1 55  ? 169.036 166.226 211.698 1.00 83.21  ? 55  CYS C N   1 
ATOM 315  C CA  . CYS A 1 55  ? 170.098 166.141 210.703 1.00 83.21  ? 55  CYS C CA  1 
ATOM 316  C C   . CYS A 1 55  ? 170.083 164.793 209.994 1.00 83.21  ? 55  CYS C C   1 
ATOM 317  O O   . CYS A 1 55  ? 170.312 164.719 208.781 1.00 83.21  ? 55  CYS C O   1 
ATOM 318  C CB  . CYS A 1 55  ? 171.453 166.386 211.363 1.00 83.21  ? 55  CYS C CB  1 
ATOM 319  S SG  . CYS A 1 55  ? 172.049 168.083 211.221 1.00 83.21  ? 55  CYS C SG  1 
ATOM 320  N N   . VAL A 1 56  ? 169.817 163.715 210.735 1.00 83.28  ? 56  VAL C N   1 
ATOM 321  C CA  . VAL A 1 56  ? 169.757 162.389 210.126 1.00 83.28  ? 56  VAL C CA  1 
ATOM 322  C C   . VAL A 1 56  ? 168.632 162.324 209.101 1.00 83.28  ? 56  VAL C C   1 
ATOM 323  O O   . VAL A 1 56  ? 168.807 161.793 207.997 1.00 83.28  ? 56  VAL C O   1 
ATOM 324  C CB  . VAL A 1 56  ? 169.597 161.309 211.212 1.00 83.28  ? 56  VAL C CB  1 
ATOM 325  C CG1 . VAL A 1 56  ? 169.075 160.017 210.609 1.00 83.28  ? 56  VAL C CG1 1 
ATOM 326  C CG2 . VAL A 1 56  ? 170.917 161.070 211.917 1.00 83.28  ? 56  VAL C CG2 1 
ATOM 327  N N   . ARG A 1 57  ? 167.463 162.865 209.447 1.00 82.60  ? 57  ARG C N   1 
ATOM 328  C CA  . ARG A 1 57  ? 166.326 162.822 208.533 1.00 82.60  ? 57  ARG C CA  1 
ATOM 329  C C   . ARG A 1 57  ? 166.612 163.592 207.250 1.00 82.60  ? 57  ARG C C   1 
ATOM 330  O O   . ARG A 1 57  ? 166.292 163.122 206.152 1.00 82.60  ? 57  ARG C O   1 
ATOM 331  C CB  . ARG A 1 57  ? 165.082 163.375 209.225 1.00 82.60  ? 57  ARG C CB  1 
ATOM 332  C CG  . ARG A 1 57  ? 163.902 163.594 208.299 1.00 82.60  ? 57  ARG C CG  1 
ATOM 333  C CD  . ARG A 1 57  ? 162.661 163.995 209.078 1.00 82.60  ? 57  ARG C CD  1 
ATOM 334  N NE  . ARG A 1 57  ? 162.488 165.443 209.124 1.00 82.60  ? 57  ARG C NE  1 
ATOM 335  C CZ  . ARG A 1 57  ? 162.117 166.191 208.093 1.00 82.60  ? 57  ARG C CZ  1 
ATOM 336  N NH1 . ARG A 1 57  ? 161.855 165.660 206.910 1.00 82.60  ? 57  ARG C NH1 1 
ATOM 337  N NH2 . ARG A 1 57  ? 162.002 167.506 208.255 1.00 82.60  ? 57  ARG C NH2 1 
ATOM 338  N N   . ARG A 1 58  ? 167.215 164.777 207.365 1.00 80.73  ? 58  ARG C N   1 
ATOM 339  C CA  . ARG A 1 58  ? 167.506 165.583 206.183 1.00 80.73  ? 58  ARG C CA  1 
ATOM 340  C C   . ARG A 1 58  ? 168.493 164.872 205.265 1.00 80.73  ? 58  ARG C C   1 
ATOM 341  O O   . ARG A 1 58  ? 168.332 164.868 204.039 1.00 80.73  ? 58  ARG C O   1 
ATOM 342  C CB  . ARG A 1 58  ? 168.048 166.949 206.603 1.00 80.73  ? 58  ARG C CB  1 
ATOM 343  C CG  . ARG A 1 58  ? 167.110 167.744 207.490 1.00 80.73  ? 58  ARG C CG  1 
ATOM 344  C CD  . ARG A 1 58  ? 167.846 168.875 208.184 1.00 80.73  ? 58  ARG C CD  1 
ATOM 345  N NE  . ARG A 1 58  ? 166.937 169.881 208.718 1.00 80.73  ? 58  ARG C NE  1 
ATOM 346  C CZ  . ARG A 1 58  ? 167.325 170.963 209.377 1.00 80.73  ? 58  ARG C CZ  1 
ATOM 347  N NH1 . ARG A 1 58  ? 168.604 171.213 209.603 1.00 80.73  ? 58  ARG C NH1 1 
ATOM 348  N NH2 . ARG A 1 58  ? 166.407 171.815 209.823 1.00 80.73  ? 58  ARG C NH2 1 
ATOM 349  N N   . VAL A 1 59  ? 169.527 164.264 205.844 1.00 77.80  ? 59  VAL C N   1 
ATOM 350  C CA  . VAL A 1 59  ? 170.546 163.568 205.066 1.00 77.80  ? 59  VAL C CA  1 
ATOM 351  C C   . VAL A 1 59  ? 169.923 162.340 204.415 1.00 77.80  ? 59  VAL C C   1 
ATOM 352  O O   . VAL A 1 59  ? 170.250 161.995 203.274 1.00 77.80  ? 59  VAL C O   1 
ATOM 353  C CB  . VAL A 1 59  ? 171.755 163.193 205.941 1.00 77.80  ? 59  VAL C CB  1 
ATOM 354  C CG1 . VAL A 1 59  ? 172.691 162.262 205.190 1.00 77.80  ? 59  VAL C CG1 1 
ATOM 355  C CG2 . VAL A 1 59  ? 172.496 164.444 206.379 1.00 77.80  ? 59  VAL C CG2 1 
ATOM 356  N N   . LEU A 1 60  ? 169.005 161.684 205.123 1.00 77.89  ? 60  LEU C N   1 
ATOM 357  C CA  . LEU A 1 60  ? 168.307 160.508 204.605 1.00 77.89  ? 60  LEU C CA  1 
ATOM 358  C C   . LEU A 1 60  ? 167.184 160.888 203.650 1.00 77.89  ? 60  LEU C C   1 
ATOM 359  O O   . LEU A 1 60  ? 166.366 160.046 203.271 1.00 77.89  ? 60  LEU C O   1 
ATOM 360  C CB  . LEU A 1 60  ? 167.768 159.658 205.750 1.00 77.89  ? 60  LEU C CB  1 
ATOM 361  C CG  . LEU A 1 60  ? 168.740 158.630 206.326 1.00 77.89  ? 60  LEU C CG  1 
ATOM 362  C CD1 . LEU A 1 60  ? 168.022 157.695 207.284 1.00 77.89  ? 60  LEU C CD1 1 
ATOM 363  C CD2 . LEU A 1 60  ? 169.408 157.849 205.209 1.00 77.89  ? 60  LEU C CD2 1 
ATOM 364  N N   . ARG A 1 61  ? 167.122 162.155 203.244 1.00 79.46  ? 61  ARG C N   1 
ATOM 365  C CA  . ARG A 1 61  ? 166.172 162.578 202.225 1.00 79.46  ? 61  ARG C CA  1 
ATOM 366  C C   . ARG A 1 61  ? 166.835 163.014 200.930 1.00 79.46  ? 61  ARG C C   1 
ATOM 367  O O   . ARG A 1 61  ? 166.152 163.063 199.904 1.00 79.46  ? 61  ARG C O   1 
ATOM 368  C CB  . ARG A 1 61  ? 165.293 163.724 202.745 1.00 79.46  ? 61  ARG C CB  1 
ATOM 369  C CG  . ARG A 1 61  ? 163.848 163.654 202.282 1.00 79.46  ? 61  ARG C CG  1 
ATOM 370  C CD  . ARG A 1 61  ? 162.959 164.575 203.103 1.00 79.46  ? 61  ARG C CD  1 
ATOM 371  N NE  . ARG A 1 61  ? 163.461 165.944 203.132 1.00 79.46  ? 61  ARG C NE  1 
ATOM 372  C CZ  . ARG A 1 61  ? 163.414 166.785 202.108 1.00 79.46  ? 61  ARG C CZ  1 
ATOM 373  N NH1 . ARG A 1 61  ? 162.879 166.436 200.949 1.00 79.46  ? 61  ARG C NH1 1 
ATOM 374  N NH2 . ARG A 1 61  ? 163.914 168.009 202.251 1.00 79.46  ? 61  ARG C NH2 1 
ATOM 375  N N   . THR A 1 62  ? 168.124 163.333 200.935 1.00 85.54  ? 62  THR C N   1 
ATOM 376  C CA  . THR A 1 62  ? 168.862 163.626 199.707 1.00 85.54  ? 62  THR C CA  1 
ATOM 377  C C   . THR A 1 62  ? 169.514 162.354 199.163 1.00 85.54  ? 62  THR C C   1 
ATOM 378  O O   . THR A 1 62  ? 170.697 162.300 198.826 1.00 85.54  ? 62  THR C O   1 
ATOM 379  C CB  . THR A 1 62  ? 169.888 164.730 199.962 1.00 85.54  ? 62  THR C CB  1 
ATOM 380  O OG1 . THR A 1 62  ? 170.575 165.047 198.744 1.00 85.54  ? 62  THR C OG1 1 
ATOM 381  C CG2 . THR A 1 62  ? 170.887 164.330 201.050 1.00 85.54  ? 62  THR C CG2 1 
ATOM 382  N N   . HIS A 1 63  ? 168.690 161.315 199.052 1.00 84.35  ? 63  HIS C N   1 
ATOM 383  C CA  . HIS A 1 63  ? 169.133 160.010 198.583 1.00 84.35  ? 63  HIS C CA  1 
ATOM 384  C C   . HIS A 1 63  ? 168.257 159.594 197.413 1.00 84.35  ? 63  HIS C C   1 
ATOM 385  O O   . HIS A 1 63  ? 167.167 159.050 197.613 1.00 84.35  ? 63  HIS C O   1 
ATOM 386  C CB  . HIS A 1 63  ? 169.060 158.969 199.704 1.00 84.35  ? 63  HIS C CB  1 
ATOM 387  C CG  . HIS A 1 63  ? 170.282 158.931 200.566 1.00 84.35  ? 63  HIS C CG  1 
ATOM 388  N ND1 . HIS A 1 63  ? 170.825 157.756 201.037 1.00 84.35  ? 63  HIS C ND1 1 
ATOM 389  C CD2 . HIS A 1 63  ? 171.068 159.926 201.040 1.00 84.35  ? 63  HIS C CD2 1 
ATOM 390  C CE1 . HIS A 1 63  ? 171.892 158.029 201.767 1.00 84.35  ? 63  HIS C CE1 1 
ATOM 391  N NE2 . HIS A 1 63  ? 172.062 159.338 201.784 1.00 84.35  ? 63  HIS C NE2 1 
ATOM 392  N N   . ARG A 1 64  ? 168.736 159.848 196.198 1.00 81.03  ? 64  ARG C N   1 
ATOM 393  C CA  . ARG A 1 64  ? 167.929 159.630 195.006 1.00 81.03  ? 64  ARG C CA  1 
ATOM 394  C C   . ARG A 1 64  ? 168.667 158.758 194.000 1.00 81.03  ? 64  ARG C C   1 
ATOM 395  O O   . ARG A 1 64  ? 168.495 158.919 192.788 1.00 81.03  ? 64  ARG C O   1 
ATOM 396  C CB  . ARG A 1 64  ? 167.556 160.971 194.372 1.00 81.03  ? 64  ARG C CB  1 
ATOM 397  C CG  . ARG A 1 64  ? 166.337 161.633 194.988 1.00 81.03  ? 64  ARG C CG  1 
ATOM 398  C CD  . ARG A 1 64  ? 166.614 163.092 195.322 1.00 81.03  ? 64  ARG C CD  1 
ATOM 399  N NE  . ARG A 1 64  ? 165.390 163.868 195.484 1.00 81.03  ? 64  ARG C NE  1 
ATOM 400  C CZ  . ARG A 1 64  ? 164.561 163.763 196.514 1.00 81.03  ? 64  ARG C CZ  1 
ATOM 401  N NH1 . ARG A 1 64  ? 164.799 162.927 197.512 1.00 81.03  ? 64  ARG C NH1 1 
ATOM 402  N NH2 . ARG A 1 64  ? 163.468 164.519 196.546 1.00 81.03  ? 64  ARG C NH2 1 
ATOM 403  N N   . SER A 1 65  ? 169.489 157.834 194.490 1.00 66.12  ? 65  SER C N   1 
ATOM 404  C CA  . SER A 1 65  ? 170.303 156.980 193.637 1.00 66.12  ? 65  SER C CA  1 
ATOM 405  C C   . SER A 1 65  ? 170.064 155.523 193.997 1.00 66.12  ? 65  SER C C   1 
ATOM 406  O O   . SER A 1 65  ? 170.060 155.165 195.178 1.00 66.12  ? 65  SER C O   1 
ATOM 407  C CB  . SER A 1 65  ? 171.791 157.321 193.776 1.00 66.12  ? 65  SER C CB  1 
ATOM 408  O OG  . SER A 1 65  ? 172.365 156.642 194.879 1.00 66.12  ? 65  SER C OG  1 
ATOM 409  N N   . VAL A 1 66  ? 169.866 154.691 192.980 1.00 52.35  ? 66  VAL C N   1 
ATOM 410  C CA  . VAL A 1 66  ? 169.711 153.256 193.184 1.00 52.35  ? 66  VAL C CA  1 
ATOM 411  C C   . VAL A 1 66  ? 171.086 152.616 193.330 1.00 52.35  ? 66  VAL C C   1 
ATOM 412  O O   . VAL A 1 66  ? 172.048 152.987 192.648 1.00 52.35  ? 66  VAL C O   1 
ATOM 413  C CB  . VAL A 1 66  ? 168.906 152.630 192.027 1.00 52.35  ? 66  VAL C CB  1 
ATOM 414  C CG1 . VAL A 1 66  ? 169.616 152.843 190.701 1.00 52.35  ? 66  VAL C CG1 1 
ATOM 415  C CG2 . VAL A 1 66  ? 168.672 151.151 192.277 1.00 52.35  ? 66  VAL C CG2 1 
ATOM 416  N N   . THR A 1 67  ? 171.187 151.654 194.244 1.00 54.50  ? 67  THR C N   1 
ATOM 417  C CA  . THR A 1 67  ? 172.434 150.953 194.509 1.00 54.50  ? 67  THR C CA  1 
ATOM 418  C C   . THR A 1 67  ? 172.203 149.455 194.387 1.00 54.50  ? 67  THR C C   1 
ATOM 419  O O   . THR A 1 67  ? 171.184 148.930 194.844 1.00 54.50  ? 67  THR C O   1 
ATOM 420  C CB  . THR A 1 67  ? 172.982 151.292 195.901 1.00 54.50  ? 67  THR C CB  1 
ATOM 421  O OG1 . THR A 1 67  ? 173.160 152.709 196.009 1.00 54.50  ? 67  THR C OG1 1 
ATOM 422  C CG2 . THR A 1 67  ? 174.315 150.603 196.140 1.00 54.50  ? 67  THR C CG2 1 
ATOM 423  N N   . TRP A 1 68  ? 173.159 148.769 193.764 1.00 59.03  ? 68  TRP C N   1 
ATOM 424  C CA  . TRP A 1 68  ? 173.028 147.351 193.470 1.00 59.03  ? 68  TRP C CA  1 
ATOM 425  C C   . TRP A 1 68  ? 174.183 146.566 194.073 1.00 59.03  ? 68  TRP C C   1 
ATOM 426  O O   . TRP A 1 68  ? 175.318 147.044 194.135 1.00 59.03  ? 68  TRP C O   1 
ATOM 427  C CB  . TRP A 1 68  ? 172.963 147.104 191.960 1.00 59.03  ? 68  TRP C CB  1 
ATOM 428  C CG  . TRP A 1 68  ? 174.217 147.453 191.223 1.00 59.03  ? 68  TRP C CG  1 
ATOM 429  C CD1 . TRP A 1 68  ? 175.258 146.621 190.941 1.00 59.03  ? 68  TRP C CD1 1 
ATOM 430  C CD2 . TRP A 1 68  ? 174.552 148.722 190.648 1.00 59.03  ? 68  TRP C CD2 1 
ATOM 431  N NE1 . TRP A 1 68  ? 176.226 147.294 190.237 1.00 59.03  ? 68  TRP C NE1 1 
ATOM 432  C CE2 . TRP A 1 68  ? 175.816 148.586 190.044 1.00 59.03  ? 68  TRP C CE2 1 
ATOM 433  C CE3 . TRP A 1 68  ? 173.908 149.961 190.592 1.00 59.03  ? 68  TRP C CE3 1 
ATOM 434  C CZ2 . TRP A 1 68  ? 176.449 149.641 189.392 1.00 59.03  ? 68  TRP C CZ2 1 
ATOM 435  C CZ3 . TRP A 1 68  ? 174.538 151.007 189.943 1.00 59.03  ? 68  TRP C CZ3 1 
ATOM 436  C CH2 . TRP A 1 68  ? 175.795 150.840 189.353 1.00 59.03  ? 68  TRP C CH2 1 
ATOM 437  N N   . ILE A 1 69  ? 173.873 145.351 194.518 1.00 62.04  ? 69  ILE C N   1 
ATOM 438  C CA  . ILE A 1 69  ? 174.848 144.423 195.075 1.00 62.04  ? 69  ILE C CA  1 
ATOM 439  C C   . ILE A 1 69  ? 174.716 143.098 194.338 1.00 62.04  ? 69  ILE C C   1 
ATOM 440  O O   . ILE A 1 69  ? 173.603 142.594 194.151 1.00 62.04  ? 69  ILE C O   1 
ATOM 441  C CB  . ILE A 1 69  ? 174.644 144.220 196.590 1.00 62.04  ? 69  ILE C CB  1 
ATOM 442  C CG1 . ILE A 1 69  ? 174.728 145.554 197.327 1.00 62.04  ? 69  ILE C CG1 1 
ATOM 443  C CG2 . ILE A 1 69  ? 175.662 143.238 197.140 1.00 62.04  ? 69  ILE C CG2 1 
ATOM 444  C CD1 . ILE A 1 69  ? 174.268 145.478 198.764 1.00 62.04  ? 69  ILE C CD1 1 
ATOM 445  N N   . SER A 1 70  ? 175.847 142.531 193.922 1.00 68.96  ? 70  SER C N   1 
ATOM 446  C CA  . SER A 1 70  ? 175.850 141.299 193.149 1.00 68.96  ? 70  SER C CA  1 
ATOM 447  C C   . SER A 1 70  ? 176.889 140.329 193.692 1.00 68.96  ? 70  SER C C   1 
ATOM 448  O O   . SER A 1 70  ? 177.780 140.700 194.459 1.00 68.96  ? 70  SER C O   1 
ATOM 449  C CB  . SER A 1 70  ? 176.124 141.567 191.668 1.00 68.96  ? 70  SER C CB  1 
ATOM 450  O OG  . SER A 1 70  ? 177.436 142.054 191.468 1.00 68.96  ? 70  SER C OG  1 
ATOM 451  N N   . ALA A 1 71  ? 176.759 139.071 193.275 1.00 82.59  ? 71  ALA C N   1 
ATOM 452  C CA  . ALA A 1 71  ? 177.670 137.998 193.661 1.00 82.59  ? 71  ALA C CA  1 
ATOM 453  C C   . ALA A 1 71  ? 178.176 137.318 192.395 1.00 82.59  ? 71  ALA C C   1 
ATOM 454  O O   . ALA A 1 71  ? 177.426 136.596 191.730 1.00 82.59  ? 71  ALA C O   1 
ATOM 455  C CB  . ALA A 1 71  ? 176.979 136.997 194.586 1.00 82.59  ? 71  ALA C CB  1 
ATOM 456  N N   . GLY A 1 72  ? 179.450 137.550 192.064 1.00 105.82 ? 72  GLY C N   1 
ATOM 457  C CA  . GLY A 1 72  ? 180.024 137.004 190.855 1.00 105.82 ? 72  GLY C CA  1 
ATOM 458  C C   . GLY A 1 72  ? 180.498 135.568 191.005 1.00 105.82 ? 72  GLY C C   1 
ATOM 459  O O   . GLY A 1 72  ? 180.367 134.949 192.059 1.00 105.82 ? 72  GLY C O   1 
ATOM 460  N N   . LEU A 1 73  ? 181.057 135.040 189.914 1.00 104.67 ? 73  LEU C N   1 
ATOM 461  C CA  . LEU A 1 73  ? 181.558 133.671 189.898 1.00 104.67 ? 73  LEU C CA  1 
ATOM 462  C C   . LEU A 1 73  ? 182.932 133.531 190.537 1.00 104.67 ? 73  LEU C C   1 
ATOM 463  O O   . LEU A 1 73  ? 183.360 132.402 190.798 1.00 104.67 ? 73  LEU C O   1 
ATOM 464  C CB  . LEU A 1 73  ? 181.611 133.150 188.461 1.00 104.67 ? 73  LEU C CB  1 
ATOM 465  C CG  . LEU A 1 73  ? 180.308 132.602 187.877 1.00 104.67 ? 73  LEU C CG  1 
ATOM 466  C CD1 . LEU A 1 73  ? 180.440 132.397 186.376 1.00 104.67 ? 73  LEU C CD1 1 
ATOM 467  C CD2 . LEU A 1 73  ? 179.917 131.305 188.566 1.00 104.67 ? 73  LEU C CD2 1 
ATOM 468  N N   . ALA A 1 74  ? 183.629 134.636 190.796 1.00 118.95 ? 74  ALA C N   1 
ATOM 469  C CA  . ALA A 1 74  ? 184.973 134.602 191.357 1.00 118.95 ? 74  ALA C CA  1 
ATOM 470  C C   . ALA A 1 74  ? 184.985 134.428 192.871 1.00 118.95 ? 74  ALA C C   1 
ATOM 471  O O   . ALA A 1 74  ? 186.018 134.687 193.502 1.00 118.95 ? 74  ALA C O   1 
ATOM 472  C CB  . ALA A 1 74  ? 185.736 135.872 190.972 1.00 118.95 ? 74  ALA C CB  1 
ATOM 473  N N   . GLU A 1 75  ? 183.876 134.003 193.468 1.00 129.06 ? 75  GLU C N   1 
ATOM 474  C CA  . GLU A 1 75  ? 183.770 133.814 194.911 1.00 129.06 ? 75  GLU C CA  1 
ATOM 475  C C   . GLU A 1 75  ? 183.107 132.480 195.225 1.00 129.06 ? 75  GLU C C   1 
ATOM 476  O O   . GLU A 1 75  ? 182.204 132.382 196.059 1.00 129.06 ? 75  GLU C O   1 
ATOM 477  C CB  . GLU A 1 75  ? 183.005 134.966 195.554 1.00 129.06 ? 75  GLU C CB  1 
ATOM 478  C CG  . GLU A 1 75  ? 183.829 136.228 195.735 1.00 129.06 ? 75  GLU C CG  1 
ATOM 479  C CD  . GLU A 1 75  ? 183.037 137.351 196.370 1.00 129.06 ? 75  GLU C CD  1 
ATOM 480  O OE1 . GLU A 1 75  ? 181.825 137.163 196.603 1.00 129.06 ? 75  GLU C OE1 1 
ATOM 481  O OE2 . GLU A 1 75  ? 183.625 138.420 196.636 1.00 129.06 ? 75  GLU C OE2 1 
ATOM 482  N N   . ALA A 1 76  ? 183.557 131.424 194.551 1.00 126.34 ? 76  ALA C N   1 
ATOM 483  C CA  . ALA A 1 76  ? 183.028 130.078 194.776 1.00 126.34 ? 76  ALA C CA  1 
ATOM 484  C C   . ALA A 1 76  ? 183.767 129.402 195.933 1.00 126.34 ? 76  ALA C C   1 
ATOM 485  O O   . ALA A 1 76  ? 184.423 128.371 195.782 1.00 126.34 ? 76  ALA C O   1 
ATOM 486  C CB  . ALA A 1 76  ? 183.119 129.254 193.498 1.00 126.34 ? 76  ALA C CB  1 
ATOM 487  N N   . GLY A 1 77  ? 183.650 130.017 197.107 1.00 128.13 ? 77  GLY C N   1 
ATOM 488  C CA  . GLY A 1 77  ? 184.286 129.506 198.305 1.00 128.13 ? 77  GLY C CA  1 
ATOM 489  C C   . GLY A 1 77  ? 183.815 128.118 198.686 1.00 128.13 ? 77  GLY C C   1 
ATOM 490  O O   . GLY A 1 77  ? 182.609 127.854 198.725 1.00 128.13 ? 77  GLY C O   1 
ATOM 491  N N   . HIS A 1 78  ? 184.758 127.220 198.969 1.00 137.79 ? 78  HIS C N   1 
ATOM 492  C CA  . HIS A 1 78  ? 184.435 125.841 199.331 1.00 137.79 ? 78  HIS C CA  1 
ATOM 493  C C   . HIS A 1 78  ? 184.138 125.736 200.829 1.00 137.79 ? 78  HIS C C   1 
ATOM 494  O O   . HIS A 1 78  ? 184.797 125.023 201.586 1.00 137.79 ? 78  HIS C O   1 
ATOM 495  C CB  . HIS A 1 78  ? 185.569 124.911 198.920 1.00 137.79 ? 78  HIS C CB  1 
ATOM 496  C CG  . HIS A 1 78  ? 185.738 124.785 197.439 1.00 137.79 ? 78  HIS C CG  1 
ATOM 497  N ND1 . HIS A 1 78  ? 186.492 125.669 196.698 1.00 137.79 ? 78  HIS C ND1 1 
ATOM 498  C CD2 . HIS A 1 78  ? 185.249 123.879 196.559 1.00 137.79 ? 78  HIS C CD2 1 
ATOM 499  C CE1 . HIS A 1 78  ? 186.461 125.313 195.426 1.00 137.79 ? 78  HIS C CE1 1 
ATOM 500  N NE2 . HIS A 1 78  ? 185.713 124.230 195.315 1.00 137.79 ? 78  HIS C NE2 1 
ATOM 501  N N   . LEU A 1 79  ? 183.114 126.475 201.248 1.00 128.86 ? 79  LEU C N   1 
ATOM 502  C CA  . LEU A 1 79  ? 182.660 126.480 202.629 1.00 128.86 ? 79  LEU C CA  1 
ATOM 503  C C   . LEU A 1 79  ? 181.140 126.497 202.660 1.00 128.86 ? 79  LEU C C   1 
ATOM 504  O O   . LEU A 1 79  ? 180.488 126.919 201.700 1.00 128.86 ? 79  LEU C O   1 
ATOM 505  C CB  . LEU A 1 79  ? 183.227 127.681 203.405 1.00 128.86 ? 79  LEU C CB  1 
ATOM 506  C CG  . LEU A 1 79  ? 182.791 129.087 202.985 1.00 128.86 ? 79  LEU C CG  1 
ATOM 507  C CD1 . LEU A 1 79  ? 181.672 129.610 203.877 1.00 128.86 ? 79  LEU C CD1 1 
ATOM 508  C CD2 . LEU A 1 79  ? 183.980 130.034 203.003 1.00 128.86 ? 79  LEU C CD2 1 
ATOM 509  N N   . GLU A 1 80  ? 180.582 126.030 203.774 1.00 127.31 ? 80  GLU C N   1 
ATOM 510  C CA  . GLU A 1 80  ? 179.135 125.953 203.918 1.00 127.31 ? 80  GLU C CA  1 
ATOM 511  C C   . GLU A 1 80  ? 178.525 127.348 203.932 1.00 127.31 ? 80  GLU C C   1 
ATOM 512  O O   . GLU A 1 80  ? 178.805 128.149 204.830 1.00 127.31 ? 80  GLU C O   1 
ATOM 513  C CB  . GLU A 1 80  ? 178.778 125.202 205.200 1.00 127.31 ? 80  GLU C CB  1 
ATOM 514  C CG  . GLU A 1 80  ? 178.594 123.705 205.015 1.00 127.31 ? 80  GLU C CG  1 
ATOM 515  C CD  . GLU A 1 80  ? 178.092 123.021 206.271 1.00 127.31 ? 80  GLU C CD  1 
ATOM 516  O OE1 . GLU A 1 80  ? 177.895 123.716 207.290 1.00 127.31 ? 80  GLU C OE1 1 
ATOM 517  O OE2 . GLU A 1 80  ? 177.895 121.788 206.240 1.00 127.31 ? 80  GLU C OE2 1 
ATOM 518  N N   . GLY A 1 81  ? 177.693 127.637 202.936 1.00 115.39 ? 81  GLY C N   1 
ATOM 519  C CA  . GLY A 1 81  ? 177.024 128.921 202.866 1.00 115.39 ? 81  GLY C CA  1 
ATOM 520  C C   . GLY A 1 81  ? 176.789 129.414 201.453 1.00 115.39 ? 81  GLY C C   1 
ATOM 521  O O   . GLY A 1 81  ? 177.621 129.202 200.565 1.00 115.39 ? 81  GLY C O   1 
ATOM 522  N N   . HIS A 1 82  ? 175.653 130.070 201.235 1.00 100.81 ? 82  HIS C N   1 
ATOM 523  C CA  . HIS A 1 82  ? 175.351 130.673 199.946 1.00 100.81 ? 82  HIS C CA  1 
ATOM 524  C C   . HIS A 1 82  ? 176.342 131.788 199.637 1.00 100.81 ? 82  HIS C C   1 
ATOM 525  O O   . HIS A 1 82  ? 176.733 132.554 200.522 1.00 100.81 ? 82  HIS C O   1 
ATOM 526  C CB  . HIS A 1 82  ? 173.924 131.222 199.940 1.00 100.81 ? 82  HIS C CB  1 
ATOM 527  C CG  . HIS A 1 82  ? 173.404 131.565 198.577 1.00 100.81 ? 82  HIS C CG  1 
ATOM 528  N ND1 . HIS A 1 82  ? 172.094 131.928 198.354 1.00 100.81 ? 82  HIS C ND1 1 
ATOM 529  C CD2 . HIS A 1 82  ? 174.016 131.608 197.370 1.00 100.81 ? 82  HIS C CD2 1 
ATOM 530  C CE1 . HIS A 1 82  ? 171.920 132.180 197.069 1.00 100.81 ? 82  HIS C CE1 1 
ATOM 531  N NE2 . HIS A 1 82  ? 173.073 131.996 196.450 1.00 100.81 ? 82  HIS C NE2 1 
ATOM 532  N N   . CYS A 1 83  ? 176.756 131.864 198.371 1.00 100.24 ? 83  CYS C N   1 
ATOM 533  C CA  . CYS A 1 83  ? 177.649 132.938 197.948 1.00 100.24 ? 83  CYS C CA  1 
ATOM 534  C C   . CYS A 1 83  ? 176.984 134.302 198.091 1.00 100.24 ? 83  CYS C C   1 
ATOM 535  O O   . CYS A 1 83  ? 177.586 135.237 198.630 1.00 100.24 ? 83  CYS C O   1 
ATOM 536  C CB  . CYS A 1 83  ? 178.094 132.709 196.504 1.00 100.24 ? 83  CYS C CB  1 
ATOM 537  S SG  . CYS A 1 83  ? 176.762 132.847 195.293 1.00 100.24 ? 83  CYS C SG  1 
ATOM 538  N N   . LEU A 1 84  ? 175.741 134.433 197.620 1.00 87.91  ? 84  LEU C N   1 
ATOM 539  C CA  . LEU A 1 84  ? 175.070 135.730 197.656 1.00 87.91  ? 84  LEU C CA  1 
ATOM 540  C C   . LEU A 1 84  ? 174.860 136.205 199.089 1.00 87.91  ? 84  LEU C C   1 
ATOM 541  O O   . LEU A 1 84  ? 175.039 137.391 199.389 1.00 87.91  ? 84  LEU C O   1 
ATOM 542  C CB  . LEU A 1 84  ? 173.736 135.652 196.908 1.00 87.91  ? 84  LEU C CB  1 
ATOM 543  C CG  . LEU A 1 84  ? 173.089 136.937 196.377 1.00 87.91  ? 84  LEU C CG  1 
ATOM 544  C CD1 . LEU A 1 84  ? 172.040 136.587 195.342 1.00 87.91  ? 84  LEU C CD1 1 
ATOM 545  C CD2 . LEU A 1 84  ? 172.461 137.780 197.475 1.00 87.91  ? 84  LEU C CD2 1 
ATOM 546  N N   . VAL A 1 85  ? 174.476 135.295 199.986 1.00 88.25  ? 85  VAL C N   1 
ATOM 547  C CA  . VAL A 1 85  ? 174.252 135.670 201.380 1.00 88.25  ? 85  VAL C CA  1 
ATOM 548  C C   . VAL A 1 85  ? 175.542 136.192 202.000 1.00 88.25  ? 85  VAL C C   1 
ATOM 549  O O   . VAL A 1 85  ? 175.532 137.129 202.808 1.00 88.25  ? 85  VAL C O   1 
ATOM 550  C CB  . VAL A 1 85  ? 173.682 134.479 202.172 1.00 88.25  ? 85  VAL C CB  1 
ATOM 551  C CG1 . VAL A 1 85  ? 173.523 134.837 203.640 1.00 88.25  ? 85  VAL C CG1 1 
ATOM 552  C CG2 . VAL A 1 85  ? 172.350 134.046 201.583 1.00 88.25  ? 85  VAL C CG2 1 
ATOM 553  N N   . ARG A 1 86  ? 176.675 135.593 201.629 1.00 96.47  ? 86  ARG C N   1 
ATOM 554  C CA  . ARG A 1 86  ? 177.959 136.045 202.155 1.00 96.47  ? 86  ARG C CA  1 
ATOM 555  C C   . ARG A 1 86  ? 178.260 137.476 201.723 1.00 96.47  ? 86  ARG C C   1 
ATOM 556  O O   . ARG A 1 86  ? 178.672 138.308 202.539 1.00 96.47  ? 86  ARG C O   1 
ATOM 557  C CB  . ARG A 1 86  ? 179.071 135.101 201.701 1.00 96.47  ? 86  ARG C CB  1 
ATOM 558  C CG  . ARG A 1 86  ? 180.442 135.472 202.234 1.00 96.47  ? 86  ARG C CG  1 
ATOM 559  C CD  . ARG A 1 86  ? 181.510 134.520 201.729 1.00 96.47  ? 86  ARG C CD  1 
ATOM 560  N NE  . ARG A 1 86  ? 182.817 134.829 202.295 1.00 96.47  ? 86  ARG C NE  1 
ATOM 561  C CZ  . ARG A 1 86  ? 183.898 134.077 202.139 1.00 96.47  ? 86  ARG C CZ  1 
ATOM 562  N NH1 . ARG A 1 86  ? 183.869 132.965 201.424 1.00 96.47  ? 86  ARG C NH1 1 
ATOM 563  N NH2 . ARG A 1 86  ? 185.037 134.452 202.715 1.00 96.47  ? 86  ARG C NH2 1 
ATOM 564  N N   . VAL A 1 87  ? 178.062 137.780 200.438 1.00 94.28  ? 87  VAL C N   1 
ATOM 565  C CA  . VAL A 1 87  ? 178.330 139.130 199.949 1.00 94.28  ? 87  VAL C CA  1 
ATOM 566  C C   . VAL A 1 87  ? 177.363 140.129 200.568 1.00 94.28  ? 87  VAL C C   1 
ATOM 567  O O   . VAL A 1 87  ? 177.762 141.225 200.980 1.00 94.28  ? 87  VAL C O   1 
ATOM 568  C CB  . VAL A 1 87  ? 178.272 139.172 198.412 1.00 94.28  ? 87  VAL C CB  1 
ATOM 569  C CG1 . VAL A 1 87  ? 178.939 140.436 197.899 1.00 94.28  ? 87  VAL C CG1 1 
ATOM 570  C CG2 . VAL A 1 87  ? 178.945 137.952 197.824 1.00 94.28  ? 87  VAL C CG2 1 
ATOM 571  N N   . VAL A 1 88  ? 176.079 139.774 200.644 1.00 90.37  ? 88  VAL C N   1 
ATOM 572  C CA  . VAL A 1 88  ? 175.087 140.706 201.171 1.00 90.37  ? 88  VAL C CA  1 
ATOM 573  C C   . VAL A 1 88  ? 175.325 140.966 202.654 1.00 90.37  ? 88  VAL C C   1 
ATOM 574  O O   . VAL A 1 88  ? 174.911 142.000 203.189 1.00 90.37  ? 88  VAL C O   1 
ATOM 575  C CB  . VAL A 1 88  ? 173.664 140.185 200.899 1.00 90.37  ? 88  VAL C CB  1 
ATOM 576  C CG1 . VAL A 1 88  ? 173.214 139.241 202.001 1.00 90.37  ? 88  VAL C CG1 1 
ATOM 577  C CG2 . VAL A 1 88  ? 172.694 141.347 200.758 1.00 90.37  ? 88  VAL C CG2 1 
ATOM 578  N N   . ALA A 1 89  ? 175.985 140.033 203.344 1.00 89.72  ? 89  ALA C N   1 
ATOM 579  C CA  . ALA A 1 89  ? 176.323 140.262 204.744 1.00 89.72  ? 89  ALA C CA  1 
ATOM 580  C C   . ALA A 1 89  ? 177.444 141.282 204.879 1.00 89.72  ? 89  ALA C C   1 
ATOM 581  O O   . ALA A 1 89  ? 177.370 142.195 205.709 1.00 89.72  ? 89  ALA C O   1 
ATOM 582  C CB  . ALA A 1 89  ? 176.713 138.945 205.413 1.00 89.72  ? 89  ALA C CB  1 
ATOM 583  N N   . GLU A 1 90  ? 178.494 141.141 204.069 1.00 93.95  ? 90  GLU C N   1 
ATOM 584  C CA  . GLU A 1 90  ? 179.629 142.053 204.155 1.00 93.95  ? 90  GLU C CA  1 
ATOM 585  C C   . GLU A 1 90  ? 179.292 143.403 203.536 1.00 93.95  ? 90  GLU C C   1 
ATOM 586  O O   . GLU A 1 90  ? 179.658 144.450 204.083 1.00 93.95  ? 90  GLU C O   1 
ATOM 587  C CB  . GLU A 1 90  ? 180.851 141.400 203.492 1.00 93.95  ? 90  GLU C CB  1 
ATOM 588  C CG  . GLU A 1 90  ? 182.239 142.056 203.698 1.00 93.95  ? 90  GLU C CG  1 
ATOM 589  C CD  . GLU A 1 90  ? 182.428 143.442 203.093 1.00 93.95  ? 90  GLU C CD  1 
ATOM 590  O OE1 . GLU A 1 90  ? 183.452 144.079 203.416 1.00 93.95  ? 90  GLU C OE1 1 
ATOM 591  O OE2 . GLU A 1 90  ? 181.640 143.859 202.219 1.00 93.95  ? 90  GLU C OE2 1 
ATOM 592  N N   . GLU A 1 91  ? 178.588 143.403 202.402 1.00 88.26  ? 91  GLU C N   1 
ATOM 593  C CA  . GLU A 1 91  ? 178.390 144.642 201.657 1.00 88.26  ? 91  GLU C CA  1 
ATOM 594  C C   . GLU A 1 91  ? 177.359 145.550 202.319 1.00 88.26  ? 91  GLU C C   1 
ATOM 595  O O   . GLU A 1 91  ? 177.476 146.777 202.242 1.00 88.26  ? 91  GLU C O   1 
ATOM 596  C CB  . GLU A 1 91  ? 177.980 144.329 200.217 1.00 88.26  ? 91  GLU C CB  1 
ATOM 597  C CG  . GLU A 1 91  ? 177.894 145.552 199.315 1.00 88.26  ? 91  GLU C CG  1 
ATOM 598  C CD  . GLU A 1 91  ? 179.243 146.216 199.090 1.00 88.26  ? 91  GLU C CD  1 
ATOM 599  O OE1 . GLU A 1 91  ? 180.272 145.513 199.153 1.00 88.26  ? 91  GLU C OE1 1 
ATOM 600  O OE2 . GLU A 1 91  ? 179.274 147.442 198.858 1.00 88.26  ? 91  GLU C OE2 1 
ATOM 601  N N   . LEU A 1 92  ? 176.345 144.974 202.973 1.00 87.57  ? 92  LEU C N   1 
ATOM 602  C CA  . LEU A 1 92  ? 175.318 145.794 203.609 1.00 87.57  ? 92  LEU C CA  1 
ATOM 603  C C   . LEU A 1 92  ? 175.880 146.659 204.727 1.00 87.57  ? 92  LEU C C   1 
ATOM 604  O O   . LEU A 1 92  ? 175.259 147.662 205.093 1.00 87.57  ? 92  LEU C O   1 
ATOM 605  C CB  . LEU A 1 92  ? 174.191 144.915 204.154 1.00 87.57  ? 92  LEU C CB  1 
ATOM 606  C CG  . LEU A 1 92  ? 172.771 145.469 204.025 1.00 87.57  ? 92  LEU C CG  1 
ATOM 607  C CD1 . LEU A 1 92  ? 172.266 145.340 202.597 1.00 87.57  ? 92  LEU C CD1 1 
ATOM 608  C CD2 . LEU A 1 92  ? 171.837 144.763 204.990 1.00 87.57  ? 92  LEU C CD2 1 
ATOM 609  N N   . GLU A 1 93  ? 177.035 146.290 205.285 1.00 87.74  ? 93  GLU C N   1 
ATOM 610  C CA  . GLU A 1 93  ? 177.675 147.135 206.286 1.00 87.74  ? 93  GLU C CA  1 
ATOM 611  C C   . GLU A 1 93  ? 178.121 148.463 205.689 1.00 87.74  ? 93  GLU C C   1 
ATOM 612  O O   . GLU A 1 93  ? 178.052 149.500 206.360 1.00 87.74  ? 93  GLU C O   1 
ATOM 613  C CB  . GLU A 1 93  ? 178.852 146.383 206.916 1.00 87.74  ? 93  GLU C CB  1 
ATOM 614  C CG  . GLU A 1 93  ? 179.906 147.245 207.605 1.00 87.74  ? 93  GLU C CG  1 
ATOM 615  C CD  . GLU A 1 93  ? 180.989 147.726 206.655 1.00 87.74  ? 93  GLU C CD  1 
ATOM 616  O OE1 . GLU A 1 93  ? 181.882 148.479 207.098 1.00 87.74  ? 93  GLU C OE1 1 
ATOM 617  O OE2 . GLU A 1 93  ? 180.950 147.345 205.467 1.00 87.74  ? 93  GLU C OE2 1 
ATOM 618  N N   . ASN A 1 94  ? 178.569 148.457 204.435 1.00 88.15  ? 94  ASN C N   1 
ATOM 619  C CA  . ASN A 1 94  ? 179.077 149.651 203.775 1.00 88.15  ? 94  ASN C CA  1 
ATOM 620  C C   . ASN A 1 94  ? 178.056 150.297 202.847 1.00 88.15  ? 94  ASN C C   1 
ATOM 621  O O   . ASN A 1 94  ? 178.410 151.217 202.102 1.00 88.15  ? 94  ASN C O   1 
ATOM 622  C CB  . ASN A 1 94  ? 180.351 149.320 202.995 1.00 88.15  ? 94  ASN C CB  1 
ATOM 623  C CG  . ASN A 1 94  ? 181.503 150.236 203.348 1.00 88.15  ? 94  ASN C CG  1 
ATOM 624  O OD1 . ASN A 1 94  ? 181.429 151.449 203.153 1.00 88.15  ? 94  ASN C OD1 1 
ATOM 625  N ND2 . ASN A 1 94  ? 182.577 149.659 203.875 1.00 88.15  ? 94  ASN C ND2 1 
ATOM 626  N N   . VAL A 1 95  ? 176.804 149.837 202.864 1.00 80.30  ? 95  VAL C N   1 
ATOM 627  C CA  . VAL A 1 95  ? 175.779 150.444 202.025 1.00 80.30  ? 95  VAL C CA  1 
ATOM 628  C C   . VAL A 1 95  ? 175.540 151.876 202.484 1.00 80.30  ? 95  VAL C C   1 
ATOM 629  O O   . VAL A 1 95  ? 175.777 152.224 203.648 1.00 80.30  ? 95  VAL C O   1 
ATOM 630  C CB  . VAL A 1 95  ? 174.484 149.614 202.062 1.00 80.30  ? 95  VAL C CB  1 
ATOM 631  C CG1 . VAL A 1 95  ? 173.709 149.877 203.344 1.00 80.30  ? 95  VAL C CG1 1 
ATOM 632  C CG2 . VAL A 1 95  ? 173.629 149.906 200.839 1.00 80.30  ? 95  VAL C CG2 1 
ATOM 633  N N   . ARG A 1 96  ? 175.091 152.724 201.562 1.00 85.82  ? 96  ARG C N   1 
ATOM 634  C CA  . ARG A 1 96  ? 174.949 154.145 201.850 1.00 85.82  ? 96  ARG C CA  1 
ATOM 635  C C   . ARG A 1 96  ? 173.502 154.609 201.925 1.00 85.82  ? 96  ARG C C   1 
ATOM 636  O O   . ARG A 1 96  ? 173.193 155.498 202.725 1.00 85.82  ? 96  ARG C O   1 
ATOM 637  C CB  . ARG A 1 96  ? 175.702 154.967 200.798 1.00 85.82  ? 96  ARG C CB  1 
ATOM 638  C CG  . ARG A 1 96  ? 175.523 156.467 200.914 1.00 85.82  ? 96  ARG C CG  1 
ATOM 639  C CD  . ARG A 1 96  ? 176.875 157.153 200.929 1.00 85.82  ? 96  ARG C CD  1 
ATOM 640  N NE  . ARG A 1 96  ? 177.568 156.924 202.192 1.00 85.82  ? 96  ARG C NE  1 
ATOM 641  C CZ  . ARG A 1 96  ? 178.826 156.521 202.297 1.00 85.82  ? 96  ARG C CZ  1 
ATOM 642  N NH1 . ARG A 1 96  ? 179.563 156.267 201.228 1.00 85.82  ? 96  ARG C NH1 1 
ATOM 643  N NH2 . ARG A 1 96  ? 179.358 156.362 203.506 1.00 85.82  ? 96  ARG C NH2 1 
ATOM 644  N N   . ILE A 1 97  ? 172.607 154.025 201.139 1.00 67.58  ? 97  ILE C N   1 
ATOM 645  C CA  . ILE A 1 97  ? 171.198 154.397 201.157 1.00 67.58  ? 97  ILE C CA  1 
ATOM 646  C C   . ILE A 1 97  ? 170.432 153.393 202.003 1.00 67.58  ? 97  ILE C C   1 
ATOM 647  O O   . ILE A 1 97  ? 170.880 152.263 202.226 1.00 67.58  ? 97  ILE C O   1 
ATOM 648  C CB  . ILE A 1 97  ? 170.615 154.476 199.731 1.00 67.58  ? 97  ILE C CB  1 
ATOM 649  C CG1 . ILE A 1 97  ? 170.404 153.071 199.167 1.00 67.58  ? 97  ILE C CG1 1 
ATOM 650  C CG2 . ILE A 1 97  ? 171.532 155.283 198.829 1.00 67.58  ? 97  ILE C CG2 1 
ATOM 651  C CD1 . ILE A 1 97  ? 170.234 153.032 197.666 1.00 67.58  ? 97  ILE C CD1 1 
ATOM 652  N N   . LEU A 1 98  ? 169.269 153.810 202.488 1.00 59.35  ? 98  LEU C N   1 
ATOM 653  C CA  . LEU A 1 98  ? 168.403 152.908 203.236 1.00 59.35  ? 98  LEU C CA  1 
ATOM 654  C C   . LEU A 1 98  ? 167.460 152.199 202.275 1.00 59.35  ? 98  LEU C C   1 
ATOM 655  O O   . LEU A 1 98  ? 166.633 152.859 201.637 1.00 59.35  ? 98  LEU C O   1 
ATOM 656  C CB  . LEU A 1 98  ? 167.610 153.674 204.288 1.00 59.35  ? 98  LEU C CB  1 
ATOM 657  C CG  . LEU A 1 98  ? 166.841 152.847 205.322 1.00 59.35  ? 98  LEU C CG  1 
ATOM 658  C CD1 . LEU A 1 98  ? 166.858 153.544 206.665 1.00 59.35  ? 98  LEU C CD1 1 
ATOM 659  C CD2 . LEU A 1 98  ? 165.406 152.611 204.884 1.00 59.35  ? 98  LEU C CD2 1 
ATOM 660  N N   . PRO A 1 99  ? 167.545 150.880 202.137 1.00 61.01  ? 99  PRO C N   1 
ATOM 661  C CA  . PRO A 1 99  ? 166.671 150.180 201.193 1.00 61.01  ? 99  PRO C CA  1 
ATOM 662  C C   . PRO A 1 99  ? 165.213 150.241 201.622 1.00 61.01  ? 99  PRO C C   1 
ATOM 663  O O   . PRO A 1 99  ? 164.876 150.174 202.805 1.00 61.01  ? 99  PRO C O   1 
ATOM 664  C CB  . PRO A 1 99  ? 167.195 148.741 201.222 1.00 61.01  ? 99  PRO C CB  1 
ATOM 665  C CG  . PRO A 1 99  ? 167.848 148.604 202.547 1.00 61.01  ? 99  PRO C CG  1 
ATOM 666  C CD  . PRO A 1 99  ? 168.396 149.955 202.903 1.00 61.01  ? 99  PRO C CD  1 
ATOM 667  N N   . HIS A 1 100 ? 164.343 150.363 200.627 1.00 72.31  ? 100 HIS C N   1 
ATOM 668  C CA  . HIS A 1 100 ? 162.901 150.366 200.842 1.00 72.31  ? 100 HIS C CA  1 
ATOM 669  C C   . HIS A 1 100 ? 162.199 149.210 200.152 1.00 72.31  ? 100 HIS C C   1 
ATOM 670  O O   . HIS A 1 100 ? 161.399 148.515 200.783 1.00 72.31  ? 100 HIS C O   1 
ATOM 671  C CB  . HIS A 1 100 ? 162.297 151.693 200.360 1.00 72.31  ? 100 HIS C CB  1 
ATOM 672  C CG  . HIS A 1 100 ? 161.248 152.244 201.273 1.00 72.31  ? 100 HIS C CG  1 
ATOM 673  N ND1 . HIS A 1 100 ? 160.452 153.316 200.932 1.00 72.31  ? 100 HIS C ND1 1 
ATOM 674  C CD2 . HIS A 1 100 ? 160.869 151.876 202.519 1.00 72.31  ? 100 HIS C CD2 1 
ATOM 675  C CE1 . HIS A 1 100 ? 159.624 153.581 201.927 1.00 72.31  ? 100 HIS C CE1 1 
ATOM 676  N NE2 . HIS A 1 100 ? 159.857 152.722 202.902 1.00 72.31  ? 100 HIS C NE2 1 
ATOM 677  N N   . THR A 1 101 ? 162.471 148.992 198.867 1.00 59.38  ? 101 THR C N   1 
ATOM 678  C CA  . THR A 1 101 ? 161.990 147.818 198.154 1.00 59.38  ? 101 THR C CA  1 
ATOM 679  C C   . THR A 1 101 ? 163.183 147.163 197.478 1.00 59.38  ? 101 THR C C   1 
ATOM 680  O O   . THR A 1 101 ? 164.031 147.853 196.907 1.00 59.38  ? 101 THR C O   1 
ATOM 681  C CB  . THR A 1 101 ? 160.924 148.170 197.110 1.00 59.38  ? 101 THR C CB  1 
ATOM 682  O OG1 . THR A 1 101 ? 161.560 148.473 195.863 1.00 59.38  ? 101 THR C OG1 1 
ATOM 683  C CG2 . THR A 1 101 ? 160.102 149.371 197.557 1.00 59.38  ? 101 THR C CG2 1 
ATOM 684  N N   . VAL A 1 102 ? 163.244 145.836 197.539 1.00 52.56  ? 102 VAL C N   1 
ATOM 685  C CA  . VAL A 1 102 ? 164.400 145.097 197.045 1.00 52.56  ? 102 VAL C CA  1 
ATOM 686  C C   . VAL A 1 102 ? 163.935 143.960 196.146 1.00 52.56  ? 102 VAL C C   1 
ATOM 687  O O   . VAL A 1 102 ? 162.966 143.258 196.454 1.00 52.56  ? 102 VAL C O   1 
ATOM 688  C CB  . VAL A 1 102 ? 165.274 144.577 198.207 1.00 52.56  ? 102 VAL C CB  1 
ATOM 689  C CG1 . VAL A 1 102 ? 164.499 143.618 199.086 1.00 52.56  ? 102 VAL C CG1 1 
ATOM 690  C CG2 . VAL A 1 102 ? 166.523 143.907 197.669 1.00 52.56  ? 102 VAL C CG2 1 
ATOM 691  N N   . LEU A 1 103 ? 164.622 143.798 195.016 1.00 45.99  ? 103 LEU C N   1 
ATOM 692  C CA  . LEU A 1 103 ? 164.390 142.711 194.071 1.00 45.99  ? 103 LEU C CA  1 
ATOM 693  C C   . LEU A 1 103 ? 165.696 141.948 193.909 1.00 45.99  ? 103 LEU C C   1 
ATOM 694  O O   . LEU A 1 103 ? 166.690 142.507 193.435 1.00 45.99  ? 103 LEU C O   1 
ATOM 695  C CB  . LEU A 1 103 ? 163.905 143.247 192.726 1.00 45.99  ? 103 LEU C CB  1 
ATOM 696  C CG  . LEU A 1 103 ? 163.489 142.195 191.697 1.00 45.99  ? 103 LEU C CG  1 
ATOM 697  C CD1 . LEU A 1 103 ? 162.705 141.079 192.359 1.00 45.99  ? 103 LEU C CD1 1 
ATOM 698  C CD2 . LEU A 1 103 ? 162.690 142.821 190.569 1.00 45.99  ? 103 LEU C CD2 1 
ATOM 699  N N   . TYR A 1 104 ? 165.698 140.677 194.300 1.00 58.26  ? 104 TYR C N   1 
ATOM 700  C CA  . TYR A 1 104 ? 166.888 139.842 194.225 1.00 58.26  ? 104 TYR C CA  1 
ATOM 701  C C   . TYR A 1 104 ? 166.572 138.537 193.510 1.00 58.26  ? 104 TYR C C   1 
ATOM 702  O O   . TYR A 1 104 ? 165.495 137.962 193.696 1.00 58.26  ? 104 TYR C O   1 
ATOM 703  C CB  . TYR A 1 104 ? 167.456 139.568 195.620 1.00 58.26  ? 104 TYR C CB  1 
ATOM 704  C CG  . TYR A 1 104 ? 166.942 138.305 196.268 1.00 58.26  ? 104 TYR C CG  1 
ATOM 705  C CD1 . TYR A 1 104 ? 165.696 138.273 196.872 1.00 58.26  ? 104 TYR C CD1 1 
ATOM 706  C CD2 . TYR A 1 104 ? 167.713 137.152 196.295 1.00 58.26  ? 104 TYR C CD2 1 
ATOM 707  C CE1 . TYR A 1 104 ? 165.227 137.126 197.473 1.00 58.26  ? 104 TYR C CE1 1 
ATOM 708  C CE2 . TYR A 1 104 ? 167.247 135.998 196.891 1.00 58.26  ? 104 TYR C CE2 1 
ATOM 709  C CZ  . TYR A 1 104 ? 166.003 135.991 197.477 1.00 58.26  ? 104 TYR C CZ  1 
ATOM 710  O OH  . TYR A 1 104 ? 165.533 134.846 198.075 1.00 58.26  ? 104 TYR C OH  1 
ATOM 711  N N   . MET A 1 105 ? 167.515 138.083 192.687 1.00 57.55  ? 105 MET C N   1 
ATOM 712  C CA  . MET A 1 105 ? 167.400 136.848 191.926 1.00 57.55  ? 105 MET C CA  1 
ATOM 713  C C   . MET A 1 105 ? 168.662 136.027 192.135 1.00 57.55  ? 105 MET C C   1 
ATOM 714  O O   . MET A 1 105 ? 169.739 136.584 192.364 1.00 57.55  ? 105 MET C O   1 
ATOM 715  C CB  . MET A 1 105 ? 167.207 137.130 190.430 1.00 57.55  ? 105 MET C CB  1 
ATOM 716  C CG  . MET A 1 105 ? 166.517 138.449 190.130 1.00 57.55  ? 105 MET C CG  1 
ATOM 717  S SD  . MET A 1 105 ? 165.938 138.592 188.430 1.00 57.55  ? 105 MET C SD  1 
ATOM 718  C CE  . MET A 1 105 ? 164.458 137.597 188.482 1.00 57.55  ? 105 MET C CE  1 
ATOM 719  N N   . ALA A 1 106 ? 168.532 134.706 192.063 1.00 67.61  ? 106 ALA C N   1 
ATOM 720  C CA  . ALA A 1 106 ? 169.680 133.820 192.193 1.00 67.61  ? 106 ALA C CA  1 
ATOM 721  C C   . ALA A 1 106 ? 169.431 132.584 191.337 1.00 67.61  ? 106 ALA C C   1 
ATOM 722  O O   . ALA A 1 106 ? 168.301 132.307 190.925 1.00 67.61  ? 106 ALA C O   1 
ATOM 723  C CB  . ALA A 1 106 ? 169.940 133.476 193.664 1.00 67.61  ? 106 ALA C CB  1 
ATOM 724  N N   . ASP A 1 107 ? 170.496 131.828 191.076 1.00 91.31  ? 107 ASP C N   1 
ATOM 725  C CA  . ASP A 1 107 ? 170.424 130.702 190.155 1.00 91.31  ? 107 ASP C CA  1 
ATOM 726  C C   . ASP A 1 107 ? 169.773 129.545 190.908 1.00 91.31  ? 107 ASP C C   1 
ATOM 727  O O   . ASP A 1 107 ? 169.662 129.587 192.137 1.00 91.31  ? 107 ASP C O   1 
ATOM 728  C CB  . ASP A 1 107 ? 171.835 130.390 189.619 1.00 91.31  ? 107 ASP C CB  1 
ATOM 729  C CG  . ASP A 1 107 ? 171.941 129.067 188.846 1.00 91.31  ? 107 ASP C CG  1 
ATOM 730  O OD1 . ASP A 1 107 ? 171.132 128.136 189.026 1.00 91.31  ? 107 ASP C OD1 1 
ATOM 731  O OD2 . ASP A 1 107 ? 172.877 128.964 188.027 1.00 91.31  ? 107 ASP C OD2 1 
ATOM 732  N N   . SER A 1 108 ? 169.342 128.508 190.188 1.00 92.72  ? 108 SER C N   1 
ATOM 733  C CA  . SER A 1 108 ? 168.494 127.463 190.750 1.00 92.72  ? 108 SER C CA  1 
ATOM 734  C C   . SER A 1 108 ? 169.302 126.267 191.241 1.00 92.72  ? 108 SER C C   1 
ATOM 735  O O   . SER A 1 108 ? 168.861 125.122 191.108 1.00 92.72  ? 108 SER C O   1 
ATOM 736  C CB  . SER A 1 108 ? 167.447 127.011 189.734 1.00 92.72  ? 108 SER C CB  1 
ATOM 737  O OG  . SER A 1 108 ? 166.402 126.296 190.368 1.00 92.72  ? 108 SER C OG  1 
ATOM 738  N N   . GLU A 1 109 ? 170.492 126.503 191.800 1.00 103.84 ? 109 GLU C N   1 
ATOM 739  C CA  . GLU A 1 109 ? 171.187 125.446 192.527 1.00 103.84 ? 109 GLU C CA  1 
ATOM 740  C C   . GLU A 1 109 ? 171.557 125.917 193.928 1.00 103.84 ? 109 GLU C C   1 
ATOM 741  O O   . GLU A 1 109 ? 172.069 125.136 194.739 1.00 103.84 ? 109 GLU C O   1 
ATOM 742  C CB  . GLU A 1 109 ? 172.439 124.971 191.781 1.00 103.84 ? 109 GLU C CB  1 
ATOM 743  C CG  . GLU A 1 109 ? 173.746 125.631 192.210 1.00 103.84 ? 109 GLU C CG  1 
ATOM 744  C CD  . GLU A 1 109 ? 174.051 126.902 191.456 1.00 103.84 ? 109 GLU C CD  1 
ATOM 745  O OE1 . GLU A 1 109 ? 173.099 127.594 191.048 1.00 103.84 ? 109 GLU C OE1 1 
ATOM 746  O OE2 . GLU A 1 109 ? 175.246 127.203 191.263 1.00 103.84 ? 109 GLU C OE2 1 
ATOM 747  N N   . THR A 1 110 ? 171.279 127.186 194.234 1.00 105.81 ? 110 THR C N   1 
ATOM 748  C CA  . THR A 1 110 ? 171.648 127.759 195.523 1.00 105.81 ? 110 THR C CA  1 
ATOM 749  C C   . THR A 1 110 ? 170.446 127.915 196.448 1.00 105.81 ? 110 THR C C   1 
ATOM 750  O O   . THR A 1 110 ? 170.517 128.677 197.419 1.00 105.81 ? 110 THR C O   1 
ATOM 751  C CB  . THR A 1 110 ? 172.326 129.114 195.335 1.00 105.81 ? 110 THR C CB  1 
ATOM 752  O OG1 . THR A 1 110 ? 171.508 129.946 194.503 1.00 105.81 ? 110 THR C OG1 1 
ATOM 753  C CG2 . THR A 1 110 ? 173.684 128.939 194.681 1.00 105.81 ? 110 THR C CG2 1 
ATOM 754  N N   . PHE A 1 111 ? 169.347 127.220 196.170 1.00 106.51 ? 111 PHE C N   1 
ATOM 755  C CA  . PHE A 1 111 ? 168.178 127.203 197.041 1.00 106.51 ? 111 PHE C CA  1 
ATOM 756  C C   . PHE A 1 111 ? 167.748 125.771 197.304 1.00 106.51 ? 111 PHE C C   1 
ATOM 757  O O   . PHE A 1 111 ? 166.593 125.500 197.644 1.00 106.51 ? 111 PHE C O   1 
ATOM 758  C CB  . PHE A 1 111 ? 167.032 128.017 196.446 1.00 106.51 ? 111 PHE C CB  1 
ATOM 759  C CG  . PHE A 1 111 ? 167.210 129.497 196.586 1.00 106.51 ? 111 PHE C CG  1 
ATOM 760  C CD1 . PHE A 1 111 ? 166.729 130.160 197.702 1.00 106.51 ? 111 PHE C CD1 1 
ATOM 761  C CD2 . PHE A 1 111 ? 167.879 130.222 195.620 1.00 106.51 ? 111 PHE C CD2 1 
ATOM 762  C CE1 . PHE A 1 111 ? 166.894 131.524 197.838 1.00 106.51 ? 111 PHE C CE1 1 
ATOM 763  C CE2 . PHE A 1 111 ? 168.049 131.582 195.754 1.00 106.51 ? 111 PHE C CE2 1 
ATOM 764  C CZ  . PHE A 1 111 ? 167.558 132.235 196.864 1.00 106.51 ? 111 PHE C CZ  1 
ATOM 765  N N   . ILE A 1 112 ? 168.681 124.835 197.148 1.00 126.36 ? 112 ILE C N   1 
ATOM 766  C CA  . ILE A 1 112 ? 168.426 123.422 197.393 1.00 126.36 ? 112 ILE C CA  1 
ATOM 767  C C   . ILE A 1 112 ? 169.493 122.888 198.336 1.00 126.36 ? 112 ILE C C   1 
ATOM 768  O O   . ILE A 1 112 ? 170.689 123.125 198.135 1.00 126.36 ? 112 ILE C O   1 
ATOM 769  C CB  . ILE A 1 112 ? 168.398 122.615 196.081 1.00 126.36 ? 112 ILE C CB  1 
ATOM 770  C CG1 . ILE A 1 112 ? 167.423 123.235 195.076 1.00 126.36 ? 112 ILE C CG1 1 
ATOM 771  C CG2 . ILE A 1 112 ? 168.047 121.162 196.353 1.00 126.36 ? 112 ILE C CG2 1 
ATOM 772  C CD1 . ILE A 1 112 ? 168.083 124.125 194.047 1.00 126.36 ? 112 ILE C CD1 1 
ATOM 773  N N   . SER A 1 113 ? 169.071 122.168 199.373 1.00 140.47 ? 113 SER C N   1 
ATOM 774  C CA  . SER A 1 113 ? 170.027 121.569 200.293 1.00 140.47 ? 113 SER C CA  1 
ATOM 775  C C   . SER A 1 113 ? 169.769 120.077 200.449 1.00 140.47 ? 113 SER C C   1 
ATOM 776  O O   . SER A 1 113 ? 170.713 119.296 200.610 1.00 140.47 ? 113 SER C O   1 
ATOM 777  C CB  . SER A 1 113 ? 169.971 122.267 201.654 1.00 140.47 ? 113 SER C CB  1 
ATOM 778  O OG  . SER A 1 113 ? 169.979 123.676 201.505 1.00 140.47 ? 113 SER C OG  1 
ATOM 779  N N   . LEU A 1 114 ? 168.501 119.665 200.404 1.00 148.81 ? 114 LEU C N   1 
ATOM 780  C CA  . LEU A 1 114 ? 168.164 118.246 200.438 1.00 148.81 ? 114 LEU C CA  1 
ATOM 781  C C   . LEU A 1 114 ? 167.516 117.782 199.136 1.00 148.81 ? 114 LEU C C   1 
ATOM 782  O O   . LEU A 1 114 ? 168.067 116.925 198.439 1.00 148.81 ? 114 LEU C O   1 
ATOM 783  C CB  . LEU A 1 114 ? 167.263 117.972 201.655 1.00 148.81 ? 114 LEU C CB  1 
ATOM 784  C CG  . LEU A 1 114 ? 166.494 116.662 201.846 1.00 148.81 ? 114 LEU C CG  1 
ATOM 785  C CD1 . LEU A 1 114 ? 166.401 116.352 203.328 1.00 148.81 ? 114 LEU C CD1 1 
ATOM 786  C CD2 . LEU A 1 114 ? 165.092 116.760 201.273 1.00 148.81 ? 114 LEU C CD2 1 
ATOM 787  N N   . GLU A 1 115 ? 166.358 118.345 198.785 1.00 145.08 ? 115 GLU C N   1 
ATOM 788  C CA  . GLU A 1 115 ? 165.772 118.157 197.462 1.00 145.08 ? 115 GLU C CA  1 
ATOM 789  C C   . GLU A 1 115 ? 165.157 119.452 196.947 1.00 145.08 ? 115 GLU C C   1 
ATOM 790  O O   . GLU A 1 115 ? 164.864 119.576 195.753 1.00 145.08 ? 115 GLU C O   1 
ATOM 791  C CB  . GLU A 1 115 ? 164.711 117.051 197.470 1.00 145.08 ? 115 GLU C CB  1 
ATOM 792  C CG  . GLU A 1 115 ? 165.204 115.680 197.900 1.00 145.08 ? 115 GLU C CG  1 
ATOM 793  C CD  . GLU A 1 115 ? 164.072 114.691 198.085 1.00 145.08 ? 115 GLU C CD  1 
ATOM 794  O OE1 . GLU A 1 115 ? 163.103 114.744 197.299 1.00 145.08 ? 115 GLU C OE1 1 
ATOM 795  O OE2 . GLU A 1 115 ? 164.150 113.861 199.015 1.00 145.08 ? 115 GLU C OE2 1 
ATOM 796  N N   . GLU A 1 116 ? 164.958 120.419 197.836 1.00 137.12 ? 116 GLU C N   1 
ATOM 797  C CA  . GLU A 1 116 ? 164.221 121.628 197.491 1.00 137.12 ? 116 GLU C CA  1 
ATOM 798  C C   . GLU A 1 116 ? 165.075 122.875 197.668 1.00 137.12 ? 116 GLU C C   1 
ATOM 799  O O   . GLU A 1 116 ? 165.432 123.240 198.787 1.00 137.12 ? 116 GLU C O   1 
ATOM 800  C CB  . GLU A 1 116 ? 162.953 121.739 198.344 1.00 137.12 ? 116 GLU C CB  1 
ATOM 801  C CG  . GLU A 1 116 ? 162.155 120.442 198.499 1.00 137.12 ? 116 GLU C CG  1 
ATOM 802  C CD  . GLU A 1 116 ? 161.482 119.961 197.218 1.00 137.12 ? 116 GLU C CD  1 
ATOM 803  O OE1 . GLU A 1 116 ? 161.792 120.472 196.122 1.00 137.12 ? 116 GLU C OE1 1 
ATOM 804  O OE2 . GLU A 1 116 ? 160.629 119.054 197.314 1.00 137.12 ? 116 GLU C OE2 1 
ATOM 805  N N   . THR A 1 127 ? 165.293 123.816 204.081 1.00 124.53 ? 127 THR C N   1 
ATOM 806  C CA  . THR A 1 127 ? 166.220 123.858 202.955 1.00 124.53 ? 127 THR C CA  1 
ATOM 807  C C   . THR A 1 127 ? 166.046 125.123 202.105 1.00 124.53 ? 127 THR C C   1 
ATOM 808  O O   . THR A 1 127 ? 166.939 125.968 202.067 1.00 124.53 ? 127 THR C O   1 
ATOM 809  C CB  . THR A 1 127 ? 166.089 122.576 202.080 1.00 124.53 ? 127 THR C CB  1 
ATOM 810  O OG1 . THR A 1 127 ? 166.901 122.695 200.903 1.00 124.53 ? 127 THR C OG1 1 
ATOM 811  C CG2 . THR A 1 127 ? 164.633 122.252 201.724 1.00 124.53 ? 127 THR C CG2 1 
ATOM 812  N N   . SER A 1 128 ? 164.906 125.258 201.424 1.00 113.78 ? 128 SER C N   1 
ATOM 813  C CA  . SER A 1 128 ? 164.631 126.482 200.681 1.00 113.78 ? 128 SER C CA  1 
ATOM 814  C C   . SER A 1 128 ? 164.439 127.656 201.629 1.00 113.78 ? 128 SER C C   1 
ATOM 815  O O   . SER A 1 128 ? 164.892 128.773 201.360 1.00 113.78 ? 128 SER C O   1 
ATOM 816  C CB  . SER A 1 128 ? 163.399 126.297 199.795 1.00 113.78 ? 128 SER C CB  1 
ATOM 817  O OG  . SER A 1 128 ? 162.929 127.545 199.317 1.00 113.78 ? 128 SER C OG  1 
ATOM 818  N N   . MET A 1 129 ? 163.759 127.416 202.749 1.00 110.81 ? 129 MET C N   1 
ATOM 819  C CA  . MET A 1 129 ? 163.523 128.446 203.751 1.00 110.81 ? 129 MET C CA  1 
ATOM 820  C C   . MET A 1 129 ? 164.834 128.946 204.343 1.00 110.81 ? 129 MET C C   1 
ATOM 821  O O   . MET A 1 129 ? 165.010 130.153 204.537 1.00 110.81 ? 129 MET C O   1 
ATOM 822  C CB  . MET A 1 129 ? 162.608 127.911 204.855 1.00 110.81 ? 129 MET C CB  1 
ATOM 823  C CG  . MET A 1 129 ? 161.548 126.939 204.360 1.00 110.81 ? 129 MET C CG  1 
ATOM 824  S SD  . MET A 1 129 ? 162.181 125.270 204.103 1.00 110.81 ? 129 MET C SD  1 
ATOM 825  C CE  . MET A 1 129 ? 162.419 124.731 205.794 1.00 110.81 ? 129 MET C CE  1 
ATOM 826  N N   . GLU A 1 130 ? 165.759 128.028 204.625 1.00 111.07 ? 130 GLU C N   1 
ATOM 827  C CA  . GLU A 1 130 ? 167.033 128.380 205.242 1.00 111.07 ? 130 GLU C CA  1 
ATOM 828  C C   . GLU A 1 130 ? 167.780 129.414 204.412 1.00 111.07 ? 130 GLU C C   1 
ATOM 829  O O   . GLU A 1 130 ? 168.268 130.413 204.948 1.00 111.07 ? 130 GLU C O   1 
ATOM 830  C CB  . GLU A 1 130 ? 167.903 127.134 205.433 1.00 111.07 ? 130 GLU C CB  1 
ATOM 831  C CG  . GLU A 1 130 ? 167.594 126.317 206.684 1.00 111.07 ? 130 GLU C CG  1 
ATOM 832  C CD  . GLU A 1 130 ? 166.165 125.806 206.734 1.00 111.07 ? 130 GLU C CD  1 
ATOM 833  O OE1 . GLU A 1 130 ? 165.527 125.689 205.666 1.00 111.07 ? 130 GLU C OE1 1 
ATOM 834  O OE2 . GLU A 1 130 ? 165.680 125.517 207.848 1.00 111.07 ? 130 GLU C OE2 1 
ATOM 835  N N   . THR A 1 131 ? 167.875 129.183 203.102 1.00 101.36 ? 131 THR C N   1 
ATOM 836  C CA  . THR A 1 131 ? 168.528 130.151 202.230 1.00 101.36 ? 131 THR C CA  1 
ATOM 837  C C   . THR A 1 131 ? 167.677 131.407 202.074 1.00 101.36 ? 131 THR C C   1 
ATOM 838  O O   . THR A 1 131 ? 168.195 132.530 202.078 1.00 101.36 ? 131 THR C O   1 
ATOM 839  C CB  . THR A 1 131 ? 168.815 129.519 200.868 1.00 101.36 ? 131 THR C CB  1 
ATOM 840  O OG1 . THR A 1 131 ? 169.707 128.411 201.038 1.00 101.36 ? 131 THR C OG1 1 
ATOM 841  C CG2 . THR A 1 131 ? 169.467 130.531 199.947 1.00 101.36 ? 131 THR C CG2 1 
ATOM 842  N N   . ALA A 1 132 ? 166.362 131.234 201.944 1.00 96.42  ? 132 ALA C N   1 
ATOM 843  C CA  . ALA A 1 132 ? 165.458 132.357 201.723 1.00 96.42  ? 132 ALA C CA  1 
ATOM 844  C C   . ALA A 1 132 ? 165.391 133.277 202.935 1.00 96.42  ? 132 ALA C C   1 
ATOM 845  O O   . ALA A 1 132 ? 165.678 134.474 202.826 1.00 96.42  ? 132 ALA C O   1 
ATOM 846  C CB  . ALA A 1 132 ? 164.057 131.853 201.372 1.00 96.42  ? 132 ALA C CB  1 
ATOM 847  N N   . LEU A 1 133 ? 165.012 132.733 204.092 1.00 97.64  ? 133 LEU C N   1 
ATOM 848  C CA  . LEU A 1 133 ? 164.852 133.540 205.296 1.00 97.64  ? 133 LEU C CA  1 
ATOM 849  C C   . LEU A 1 133 ? 166.170 134.167 205.732 1.00 97.64  ? 133 LEU C C   1 
ATOM 850  O O   . LEU A 1 133 ? 166.172 135.184 206.433 1.00 97.64  ? 133 LEU C O   1 
ATOM 851  C CB  . LEU A 1 133 ? 164.263 132.707 206.436 1.00 97.64  ? 133 LEU C CB  1 
ATOM 852  C CG  . LEU A 1 133 ? 162.978 131.936 206.136 1.00 97.64  ? 133 LEU C CG  1 
ATOM 853  C CD1 . LEU A 1 133 ? 162.821 130.772 207.099 1.00 97.64  ? 133 LEU C CD1 1 
ATOM 854  C CD2 . LEU A 1 133 ? 161.774 132.860 206.205 1.00 97.64  ? 133 LEU C CD2 1 
ATOM 855  N N   . ALA A 1 134 ? 167.292 133.566 205.332 1.00 96.69  ? 134 ALA C N   1 
ATOM 856  C CA  . ALA A 1 134 ? 168.594 134.154 205.627 1.00 96.69  ? 134 ALA C CA  1 
ATOM 857  C C   . ALA A 1 134 ? 168.697 135.556 205.041 1.00 96.69  ? 134 ALA C C   1 
ATOM 858  O O   . ALA A 1 134 ? 169.078 136.508 205.729 1.00 96.69  ? 134 ALA C O   1 
ATOM 859  C CB  . ALA A 1 134 ? 169.710 133.257 205.089 1.00 96.69  ? 134 ALA C CB  1 
ATOM 860  N N   . LEU A 1 135 ? 168.345 135.700 203.762 1.00 89.97  ? 135 LEU C N   1 
ATOM 861  C CA  . LEU A 1 135 ? 168.345 137.021 203.144 1.00 89.97  ? 135 LEU C CA  1 
ATOM 862  C C   . LEU A 1 135 ? 167.161 137.852 203.622 1.00 89.97  ? 135 LEU C C   1 
ATOM 863  O O   . LEU A 1 135 ? 167.214 139.087 203.611 1.00 89.97  ? 135 LEU C O   1 
ATOM 864  C CB  . LEU A 1 135 ? 168.335 136.886 201.622 1.00 89.97  ? 135 LEU C CB  1 
ATOM 865  C CG  . LEU A 1 135 ? 168.664 138.136 200.804 1.00 89.97  ? 135 LEU C CG  1 
ATOM 866  C CD1 . LEU A 1 135 ? 169.680 139.007 201.518 1.00 89.97  ? 135 LEU C CD1 1 
ATOM 867  C CD2 . LEU A 1 135 ? 169.180 137.744 199.433 1.00 89.97  ? 135 LEU C CD2 1 
ATOM 868  N N   . GLU A 1 136 ? 166.085 137.193 204.047 1.00 88.64  ? 136 GLU C N   1 
ATOM 869  C CA  . GLU A 1 136 ? 164.891 137.899 204.497 1.00 88.64  ? 136 GLU C CA  1 
ATOM 870  C C   . GLU A 1 136 ? 165.088 138.479 205.893 1.00 88.64  ? 136 GLU C C   1 
ATOM 871  O O   . GLU A 1 136 ? 164.254 139.256 206.369 1.00 88.64  ? 136 GLU C O   1 
ATOM 872  C CB  . GLU A 1 136 ? 163.681 136.963 204.474 1.00 88.64  ? 136 GLU C CB  1 
ATOM 873  C CG  . GLU A 1 136 ? 162.355 137.662 204.220 1.00 88.64  ? 136 GLU C CG  1 
ATOM 874  C CD  . GLU A 1 136 ? 161.165 136.736 204.385 1.00 88.64  ? 136 GLU C CD  1 
ATOM 875  O OE1 . GLU A 1 136 ? 161.233 135.586 203.905 1.00 88.64  ? 136 GLU C OE1 1 
ATOM 876  O OE2 . GLU A 1 136 ? 160.161 137.159 204.994 1.00 88.64  ? 136 GLU C OE2 1 
ATOM 877  N N   . LYS A 1 137 ? 166.185 138.111 206.555 1.00 93.40  ? 137 LYS C N   1 
ATOM 878  C CA  . LYS A 1 137 ? 166.468 138.567 207.913 1.00 93.40  ? 137 LYS C CA  1 
ATOM 879  C C   . LYS A 1 137 ? 167.376 139.792 207.934 1.00 93.40  ? 137 LYS C C   1 
ATOM 880  O O   . LYS A 1 137 ? 167.148 140.723 208.712 1.00 93.40  ? 137 LYS C O   1 
ATOM 881  C CB  . LYS A 1 137 ? 167.092 137.427 208.729 1.00 93.40  ? 137 LYS C CB  1 
ATOM 882  C CG  . LYS A 1 137 ? 166.079 136.554 209.449 1.00 93.40  ? 137 LYS C CG  1 
ATOM 883  C CD  . LYS A 1 137 ? 166.765 135.468 210.261 1.00 93.40  ? 137 LYS C CD  1 
ATOM 884  C CE  . LYS A 1 137 ? 167.072 134.249 209.407 1.00 93.40  ? 137 LYS C CE  1 
ATOM 885  N NZ  . LYS A 1 137 ? 167.041 132.992 210.203 1.00 93.40  ? 137 LYS C NZ  1 
ATOM 886  N N   . LEU A 1 138 ? 168.413 139.804 207.093 1.00 91.00  ? 138 LEU C N   1 
ATOM 887  C CA  . LEU A 1 138 ? 169.347 140.925 207.064 1.00 91.00  ? 138 LEU C CA  1 
ATOM 888  C C   . LEU A 1 138 ? 168.667 142.220 206.638 1.00 91.00  ? 138 LEU C C   1 
ATOM 889  O O   . LEU A 1 138 ? 168.950 143.292 207.181 1.00 91.00  ? 138 LEU C O   1 
ATOM 890  C CB  . LEU A 1 138 ? 170.516 140.606 206.130 1.00 91.00  ? 138 LEU C CB  1 
ATOM 891  C CG  . LEU A 1 138 ? 171.689 139.823 206.722 1.00 91.00  ? 138 LEU C CG  1 
ATOM 892  C CD1 . LEU A 1 138 ? 171.345 138.359 206.919 1.00 91.00  ? 138 LEU C CD1 1 
ATOM 893  C CD2 . LEU A 1 138 ? 172.905 139.967 205.829 1.00 91.00  ? 138 LEU C CD2 1 
ATOM 894  N N   . PHE A 1 139 ? 167.772 142.137 205.659 1.00 84.25  ? 139 PHE C N   1 
ATOM 895  C CA  . PHE A 1 139 ? 167.107 143.327 205.159 1.00 84.25  ? 139 PHE C CA  1 
ATOM 896  C C   . PHE A 1 139 ? 166.187 143.909 206.233 1.00 84.25  ? 139 PHE C C   1 
ATOM 897  O O   . PHE A 1 139 ? 165.700 143.183 207.105 1.00 84.25  ? 139 PHE C O   1 
ATOM 898  C CB  . PHE A 1 139 ? 166.316 142.991 203.897 1.00 84.25  ? 139 PHE C CB  1 
ATOM 899  C CG  . PHE A 1 139 ? 167.147 142.995 202.648 1.00 84.25  ? 139 PHE C CG  1 
ATOM 900  C CD1 . PHE A 1 139 ? 168.247 143.828 202.536 1.00 84.25  ? 139 PHE C CD1 1 
ATOM 901  C CD2 . PHE A 1 139 ? 166.842 142.153 201.594 1.00 84.25  ? 139 PHE C CD2 1 
ATOM 902  C CE1 . PHE A 1 139 ? 169.017 143.831 201.391 1.00 84.25  ? 139 PHE C CE1 1 
ATOM 903  C CE2 . PHE A 1 139 ? 167.611 142.150 200.448 1.00 84.25  ? 139 PHE C CE2 1 
ATOM 904  C CZ  . PHE A 1 139 ? 168.699 142.991 200.346 1.00 84.25  ? 139 PHE C CZ  1 
ATOM 905  N N   . PRO A 1 140 ? 165.945 145.221 206.202 1.00 96.30  ? 140 PRO C N   1 
ATOM 906  C CA  . PRO A 1 140 ? 165.129 145.848 207.248 1.00 96.30  ? 140 PRO C CA  1 
ATOM 907  C C   . PRO A 1 140 ? 163.708 145.301 207.267 1.00 96.30  ? 140 PRO C C   1 
ATOM 908  O O   . PRO A 1 140 ? 163.178 144.851 206.248 1.00 96.30  ? 140 PRO C O   1 
ATOM 909  C CB  . PRO A 1 140 ? 165.150 147.335 206.875 1.00 96.30  ? 140 PRO C CB  1 
ATOM 910  C CG  . PRO A 1 140 ? 166.330 147.500 205.986 1.00 96.30  ? 140 PRO C CG  1 
ATOM 911  C CD  . PRO A 1 140 ? 166.491 146.208 205.256 1.00 96.30  ? 140 PRO C CD  1 
ATOM 912  N N   . LYS A 1 141 ? 163.098 145.333 208.454 1.00 104.27 ? 141 LYS C N   1 
ATOM 913  C CA  . LYS A 1 141 ? 161.738 144.827 208.607 1.00 104.27 ? 141 LYS C CA  1 
ATOM 914  C C   . LYS A 1 141 ? 160.749 145.626 207.766 1.00 104.27 ? 141 LYS C C   1 
ATOM 915  O O   . LYS A 1 141 ? 159.858 145.051 207.131 1.00 104.27 ? 141 LYS C O   1 
ATOM 916  C CB  . LYS A 1 141 ? 161.332 144.853 210.082 1.00 104.27 ? 141 LYS C CB  1 
ATOM 917  C CG  . LYS A 1 141 ? 160.092 144.029 210.420 1.00 104.27 ? 141 LYS C CG  1 
ATOM 918  C CD  . LYS A 1 141 ? 160.036 142.707 209.662 1.00 104.27 ? 141 LYS C CD  1 
ATOM 919  C CE  . LYS A 1 141 ? 161.119 141.740 210.127 1.00 104.27 ? 141 LYS C CE  1 
ATOM 920  N NZ  . LYS A 1 141 ? 161.271 140.588 209.194 1.00 104.27 ? 141 LYS C NZ  1 
ATOM 921  N N   . GLN A 1 142 ? 160.887 146.952 207.750 1.00 102.03 ? 142 GLN C N   1 
ATOM 922  C CA  . GLN A 1 142 ? 160.009 147.791 206.945 1.00 102.03 ? 142 GLN C CA  1 
ATOM 923  C C   . GLN A 1 142 ? 160.253 147.641 205.450 1.00 102.03 ? 142 GLN C C   1 
ATOM 924  O O   . GLN A 1 142 ? 159.373 147.996 204.659 1.00 102.03 ? 142 GLN C O   1 
ATOM 925  C CB  . GLN A 1 142 ? 160.165 149.268 207.335 1.00 102.03 ? 142 GLN C CB  1 
ATOM 926  C CG  . GLN A 1 142 ? 159.682 149.664 208.740 1.00 102.03 ? 142 GLN C CG  1 
ATOM 927  C CD  . GLN A 1 142 ? 160.451 149.018 209.888 1.00 102.03 ? 142 GLN C CD  1 
ATOM 928  O OE1 . GLN A 1 142 ? 161.257 148.108 209.692 1.00 102.03 ? 142 GLN C OE1 1 
ATOM 929  N NE2 . GLN A 1 142 ? 160.202 149.501 211.100 1.00 102.03 ? 142 GLN C NE2 1 
ATOM 930  N N   . CYS A 1 143 ? 161.413 147.130 205.047 1.00 84.74  ? 143 CYS C N   1 
ATOM 931  C CA  . CYS A 1 143 ? 161.713 146.963 203.634 1.00 84.74  ? 143 CYS C CA  1 
ATOM 932  C C   . CYS A 1 143 ? 160.842 145.871 203.023 1.00 84.74  ? 143 CYS C C   1 
ATOM 933  O O   . CYS A 1 143 ? 160.435 144.918 203.693 1.00 84.74  ? 143 CYS C O   1 
ATOM 934  C CB  . CYS A 1 143 ? 163.190 146.624 203.439 1.00 84.74  ? 143 CYS C CB  1 
ATOM 935  S SG  . CYS A 1 143 ? 163.710 146.508 201.715 1.00 84.74  ? 143 CYS C SG  1 
ATOM 936  N N   . GLN A 1 144 ? 160.557 146.019 201.733 1.00 69.91  ? 144 GLN C N   1 
ATOM 937  C CA  . GLN A 1 144 ? 159.718 145.081 200.999 1.00 69.91  ? 144 GLN C CA  1 
ATOM 938  C C   . GLN A 1 144 ? 160.606 144.202 200.127 1.00 69.91  ? 144 GLN C C   1 
ATOM 939  O O   . GLN A 1 144 ? 161.393 144.713 199.323 1.00 69.91  ? 144 GLN C O   1 
ATOM 940  C CB  . GLN A 1 144 ? 158.689 145.828 200.152 1.00 69.91  ? 144 GLN C CB  1 
ATOM 941  C CG  . GLN A 1 144 ? 157.330 145.163 200.108 1.00 69.91  ? 144 GLN C CG  1 
ATOM 942  C CD  . GLN A 1 144 ? 156.201 146.167 200.037 1.00 69.91  ? 144 GLN C CD  1 
ATOM 943  O OE1 . GLN A 1 144 ? 156.432 147.366 199.879 1.00 69.91  ? 144 GLN C OE1 1 
ATOM 944  N NE2 . GLN A 1 144 ? 154.971 145.685 200.158 1.00 69.91  ? 144 GLN C NE2 1 
ATOM 945  N N   . VAL A 1 145 ? 160.476 142.887 200.285 1.00 64.31  ? 145 VAL C N   1 
ATOM 946  C CA  . VAL A 1 145 ? 161.357 141.919 199.642 1.00 64.31  ? 145 VAL C CA  1 
ATOM 947  C C   . VAL A 1 145 ? 160.533 141.027 198.727 1.00 64.31  ? 145 VAL C C   1 
ATOM 948  O O   . VAL A 1 145 ? 159.523 140.454 199.153 1.00 64.31  ? 145 VAL C O   1 
ATOM 949  C CB  . VAL A 1 145 ? 162.114 141.074 200.682 1.00 64.31  ? 145 VAL C CB  1 
ATOM 950  C CG1 . VAL A 1 145 ? 163.230 140.288 200.016 1.00 64.31  ? 145 VAL C CG1 1 
ATOM 951  C CG2 . VAL A 1 145 ? 162.660 141.957 201.791 1.00 64.31  ? 145 VAL C CG2 1 
ATOM 952  N N   . LEU A 1 146 ? 160.966 140.906 197.475 1.00 55.30  ? 146 LEU C N   1 
ATOM 953  C CA  . LEU A 1 146 ? 160.410 139.948 196.531 1.00 55.30  ? 146 LEU C CA  1 
ATOM 954  C C   . LEU A 1 146 ? 161.489 138.937 196.174 1.00 55.30  ? 146 LEU C C   1 
ATOM 955  O O   . LEU A 1 146 ? 162.576 139.311 195.723 1.00 55.30  ? 146 LEU C O   1 
ATOM 956  C CB  . LEU A 1 146 ? 159.887 140.643 195.266 1.00 55.30  ? 146 LEU C CB  1 
ATOM 957  C CG  . LEU A 1 146 ? 159.039 139.818 194.292 1.00 55.30  ? 146 LEU C CG  1 
ATOM 958  C CD1 . LEU A 1 146 ? 158.072 140.719 193.548 1.00 55.30  ? 146 LEU C CD1 1 
ATOM 959  C CD2 . LEU A 1 146 ? 159.891 139.044 193.301 1.00 55.30  ? 146 LEU C CD2 1 
ATOM 960  N N   . GLY A 1 147 ? 161.184 137.657 196.363 1.00 63.63  ? 147 GLY C N   1 
ATOM 961  C CA  . GLY A 1 147 ? 162.175 136.619 196.158 1.00 63.63  ? 147 GLY C CA  1 
ATOM 962  C C   . GLY A 1 147 ? 161.872 135.684 195.008 1.00 63.63  ? 147 GLY C C   1 
ATOM 963  O O   . GLY A 1 147 ? 160.919 134.903 195.069 1.00 63.63  ? 147 GLY C O   1 
ATOM 964  N N   . ILE A 1 148 ? 162.694 135.738 193.965 1.00 57.68  ? 148 ILE C N   1 
ATOM 965  C CA  . ILE A 1 148 ? 162.457 135.016 192.723 1.00 57.68  ? 148 ILE C CA  1 
ATOM 966  C C   . ILE A 1 148 ? 163.735 134.295 192.316 1.00 57.68  ? 148 ILE C C   1 
ATOM 967  O O   . ILE A 1 148 ? 164.825 134.873 192.359 1.00 57.68  ? 148 ILE C O   1 
ATOM 968  C CB  . ILE A 1 148 ? 161.980 135.981 191.619 1.00 57.68  ? 148 ILE C CB  1 
ATOM 969  C CG1 . ILE A 1 148 ? 162.007 135.314 190.248 1.00 57.68  ? 148 ILE C CG1 1 
ATOM 970  C CG2 . ILE A 1 148 ? 162.807 137.250 191.631 1.00 57.68  ? 148 ILE C CG2 1 
ATOM 971  C CD1 . ILE A 1 148 ? 161.214 136.072 189.214 1.00 57.68  ? 148 ILE C CD1 1 
ATOM 972  N N   . VAL A 1 149 ? 163.597 133.029 191.929 1.00 67.14  ? 149 VAL C N   1 
ATOM 973  C CA  . VAL A 1 149 ? 164.722 132.181 191.550 1.00 67.14  ? 149 VAL C CA  1 
ATOM 974  C C   . VAL A 1 149 ? 164.568 131.797 190.086 1.00 67.14  ? 149 VAL C C   1 
ATOM 975  O O   . VAL A 1 149 ? 163.495 131.348 189.664 1.00 67.14  ? 149 VAL C O   1 
ATOM 976  C CB  . VAL A 1 149 ? 164.807 130.929 192.437 1.00 67.14  ? 149 VAL C CB  1 
ATOM 977  C CG1 . VAL A 1 149 ? 166.102 130.180 192.173 1.00 67.14  ? 149 VAL C CG1 1 
ATOM 978  C CG2 . VAL A 1 149 ? 164.697 131.312 193.902 1.00 67.14  ? 149 VAL C CG2 1 
ATOM 979  N N   . THR A 1 150 ? 165.640 131.969 189.313 1.00 66.70  ? 150 THR C N   1 
ATOM 980  C CA  . THR A 1 150 ? 165.622 131.722 187.877 1.00 66.70  ? 150 THR C CA  1 
ATOM 981  C C   . THR A 1 150 ? 166.778 130.808 187.490 1.00 66.70  ? 150 THR C C   1 
ATOM 982  O O   . THR A 1 150 ? 167.791 130.762 188.199 1.00 66.70  ? 150 THR C O   1 
ATOM 983  C CB  . THR A 1 150 ? 165.720 133.037 187.102 1.00 66.70  ? 150 THR C CB  1 
ATOM 984  O OG1 . THR A 1 150 ? 167.025 133.597 187.283 1.00 66.70  ? 150 THR C OG1 1 
ATOM 985  C CG2 . THR A 1 150 ? 164.689 134.032 187.598 1.00 66.70  ? 150 THR C CG2 1 
ATOM 986  N N   . PRO A 1 151 ? 166.677 130.068 186.380 1.00 61.17  ? 151 PRO C N   1 
ATOM 987  C CA  . PRO A 1 151 ? 167.817 129.254 185.942 1.00 61.17  ? 151 PRO C CA  1 
ATOM 988  C C   . PRO A 1 151 ? 168.799 130.051 185.101 1.00 61.17  ? 151 PRO C C   1 
ATOM 989  O O   . PRO A 1 151 ? 168.917 129.831 183.892 1.00 61.17  ? 151 PRO C O   1 
ATOM 990  C CB  . PRO A 1 151 ? 167.155 128.136 185.129 1.00 61.17  ? 151 PRO C CB  1 
ATOM 991  C CG  . PRO A 1 151 ? 165.885 128.736 184.618 1.00 61.17  ? 151 PRO C CG  1 
ATOM 992  C CD  . PRO A 1 151 ? 165.515 129.915 185.487 1.00 61.17  ? 151 PRO C CD  1 
ATOM 993  N N   . GLY A 1 152 ? 169.511 130.977 185.734 1.00 55.58  ? 152 GLY C N   1 
ATOM 994  C CA  . GLY A 1 152 ? 170.460 131.818 185.033 1.00 55.58  ? 152 GLY C CA  1 
ATOM 995  C C   . GLY A 1 152 ? 170.368 133.270 185.452 1.00 55.58  ? 152 GLY C C   1 
ATOM 996  O O   . GLY A 1 152 ? 169.280 133.852 185.465 1.00 55.58  ? 152 GLY C O   1 
ATOM 997  N N   . ILE A 1 153 ? 171.508 133.866 185.790 1.00 57.43  ? 153 ILE C N   1 
ATOM 998  C CA  . ILE A 1 153 ? 171.578 135.248 186.252 1.00 57.43  ? 153 ILE C CA  1 
ATOM 999  C C   . ILE A 1 153 ? 172.526 136.012 185.342 1.00 57.43  ? 153 ILE C C   1 
ATOM 1000 O O   . ILE A 1 153 ? 173.642 135.554 185.078 1.00 57.43  ? 153 ILE C O   1 
ATOM 1001 C CB  . ILE A 1 153 ? 172.063 135.341 187.711 1.00 57.43  ? 153 ILE C CB  1 
ATOM 1002 C CG1 . ILE A 1 153 ? 171.185 134.508 188.648 1.00 57.43  ? 153 ILE C CG1 1 
ATOM 1003 C CG2 . ILE A 1 153 ? 172.106 136.787 188.159 1.00 57.43  ? 153 ILE C CG2 1 
ATOM 1004 C CD1 . ILE A 1 153 ? 169.708 134.756 188.497 1.00 57.43  ? 153 ILE C CD1 1 
ATOM 1005 N N   . VAL A 1 154 ? 172.088 137.172 184.862 1.00 54.57  ? 154 VAL C N   1 
ATOM 1006 C CA  . VAL A 1 154 ? 172.916 138.062 184.056 1.00 54.57  ? 154 VAL C CA  1 
ATOM 1007 C C   . VAL A 1 154 ? 172.994 139.397 184.781 1.00 54.57  ? 154 VAL C C   1 
ATOM 1008 O O   . VAL A 1 154 ? 171.960 140.022 185.046 1.00 54.57  ? 154 VAL C O   1 
ATOM 1009 C CB  . VAL A 1 154 ? 172.340 138.224 182.641 1.00 54.57  ? 154 VAL C CB  1 
ATOM 1010 C CG1 . VAL A 1 154 ? 173.146 139.228 181.846 1.00 54.57  ? 154 VAL C CG1 1 
ATOM 1011 C CG2 . VAL A 1 154 ? 172.294 136.886 181.942 1.00 54.57  ? 154 VAL C CG2 1 
ATOM 1012 N N   . VAL A 1 155 ? 174.209 139.842 185.098 1.00 56.02  ? 155 VAL C N   1 
ATOM 1013 C CA  . VAL A 1 155 ? 174.373 140.864 186.129 1.00 56.02  ? 155 VAL C CA  1 
ATOM 1014 C C   . VAL A 1 155 ? 175.589 141.732 185.828 1.00 56.02  ? 155 VAL C C   1 
ATOM 1015 O O   . VAL A 1 155 ? 176.571 141.268 185.242 1.00 56.02  ? 155 VAL C O   1 
ATOM 1016 C CB  . VAL A 1 155 ? 174.502 140.212 187.519 1.00 56.02  ? 155 VAL C CB  1 
ATOM 1017 C CG1 . VAL A 1 155 ? 175.682 139.254 187.548 1.00 56.02  ? 155 VAL C CG1 1 
ATOM 1018 C CG2 . VAL A 1 155 ? 174.621 141.261 188.595 1.00 56.02  ? 155 VAL C CG2 1 
ATOM 1019 N N   . THR A 1 156 ? 175.506 143.004 186.227 1.00 58.78  ? 156 THR C N   1 
ATOM 1020 C CA  . THR A 1 156 ? 176.637 143.927 186.227 1.00 58.78  ? 156 THR C CA  1 
ATOM 1021 C C   . THR A 1 156 ? 177.274 143.952 187.615 1.00 58.78  ? 156 THR C C   1 
ATOM 1022 O O   . THR A 1 156 ? 176.554 144.016 188.616 1.00 58.78  ? 156 THR C O   1 
ATOM 1023 C CB  . THR A 1 156 ? 176.170 145.330 185.841 1.00 58.78  ? 156 THR C CB  1 
ATOM 1024 O OG1 . THR A 1 156 ? 175.370 145.260 184.654 1.00 58.78  ? 156 THR C OG1 1 
ATOM 1025 C CG2 . THR A 1 156 ? 177.349 146.254 185.587 1.00 58.78  ? 156 THR C CG2 1 
ATOM 1026 N N   . PRO A 1 157 ? 178.598 143.895 187.720 1.00 66.70  ? 157 PRO C N   1 
ATOM 1027 C CA  . PRO A 1 157 ? 179.245 143.891 189.037 1.00 66.70  ? 157 PRO C CA  1 
ATOM 1028 C C   . PRO A 1 157 ? 179.186 145.260 189.707 1.00 66.70  ? 157 PRO C C   1 
ATOM 1029 O O   . PRO A 1 157 ? 178.702 146.243 189.144 1.00 66.70  ? 157 PRO C O   1 
ATOM 1030 C CB  . PRO A 1 157 ? 180.695 143.487 188.729 1.00 66.70  ? 157 PRO C CB  1 
ATOM 1031 C CG  . PRO A 1 157 ? 180.715 143.106 187.269 1.00 66.70  ? 157 PRO C CG  1 
ATOM 1032 C CD  . PRO A 1 157 ? 179.581 143.815 186.630 1.00 66.70  ? 157 PRO C CD  1 
ATOM 1033 N N   . MET A 1 158 ? 179.700 145.306 190.937 1.00 75.35  ? 158 MET C N   1 
ATOM 1034 C CA  . MET A 1 158 ? 179.646 146.518 191.740 1.00 75.35  ? 158 MET C CA  1 
ATOM 1035 C C   . MET A 1 158 ? 180.527 147.609 191.134 1.00 75.35  ? 158 MET C C   1 
ATOM 1036 O O   . MET A 1 158 ? 181.216 147.415 190.131 1.00 75.35  ? 158 MET C O   1 
ATOM 1037 C CB  . MET A 1 158 ? 180.096 146.277 193.189 1.00 75.35  ? 158 MET C CB  1 
ATOM 1038 C CG  . MET A 1 158 ? 179.170 145.458 194.102 1.00 75.35  ? 158 MET C CG  1 
ATOM 1039 S SD  . MET A 1 158 ? 178.574 143.814 193.635 1.00 75.35  ? 158 MET C SD  1 
ATOM 1040 C CE  . MET A 1 158 ? 180.022 143.081 192.869 1.00 75.35  ? 158 MET C CE  1 
ATOM 1041 N N   . GLY A 1 159 ? 180.497 148.778 191.770 1.00 73.95  ? 159 GLY C N   1 
ATOM 1042 C CA  . GLY A 1 159 ? 181.366 149.867 191.377 1.00 73.95  ? 159 GLY C CA  1 
ATOM 1043 C C   . GLY A 1 159 ? 180.637 151.004 190.697 1.00 73.95  ? 159 GLY C C   1 
ATOM 1044 O O   . GLY A 1 159 ? 179.768 151.644 191.296 1.00 73.95  ? 159 GLY C O   1 
ATOM 1045 N N   . SER A 1 160 ? 180.983 151.265 189.443 1.00 66.96  ? 160 SER C N   1 
ATOM 1046 C CA  . SER A 1 160 ? 180.365 152.320 188.659 1.00 66.96  ? 160 SER C CA  1 
ATOM 1047 C C   . SER A 1 160 ? 179.435 151.718 187.614 1.00 66.96  ? 160 SER C C   1 
ATOM 1048 O O   . SER A 1 160 ? 179.188 150.510 187.583 1.00 66.96  ? 160 SER C O   1 
ATOM 1049 C CB  . SER A 1 160 ? 181.429 153.197 187.989 1.00 66.96  ? 160 SER C CB  1 
ATOM 1050 O OG  . SER A 1 160 ? 180.843 154.064 187.035 1.00 66.96  ? 160 SER C OG  1 
ATOM 1051 N N   . GLY A 1 161 ? 178.910 152.587 186.758 1.00 60.84  ? 161 GLY C N   1 
ATOM 1052 C CA  . GLY A 1 161 ? 178.054 152.170 185.672 1.00 60.84  ? 161 GLY C CA  1 
ATOM 1053 C C   . GLY A 1 161 ? 178.770 151.713 184.425 1.00 60.84  ? 161 GLY C C   1 
ATOM 1054 O O   . GLY A 1 161 ? 178.117 151.391 183.430 1.00 60.84  ? 161 GLY C O   1 
ATOM 1055 N N   . SER A 1 162 ? 180.100 151.676 184.444 1.00 63.97  ? 162 SER C N   1 
ATOM 1056 C CA  . SER A 1 162 ? 180.889 151.309 183.278 1.00 63.97  ? 162 SER C CA  1 
ATOM 1057 C C   . SER A 1 162 ? 181.401 149.877 183.322 1.00 63.97  ? 162 SER C C   1 
ATOM 1058 O O   . SER A 1 162 ? 182.180 149.488 182.447 1.00 63.97  ? 162 SER C O   1 
ATOM 1059 C CB  . SER A 1 162 ? 182.072 152.268 183.120 1.00 63.97  ? 162 SER C CB  1 
ATOM 1060 O OG  . SER A 1 162 ? 182.505 152.317 181.772 1.00 63.97  ? 162 SER C OG  1 
ATOM 1061 N N   . ASN A 1 163 ? 180.997 149.089 184.314 1.00 66.73  ? 163 ASN C N   1 
ATOM 1062 C CA  . ASN A 1 163 ? 181.440 147.706 184.379 1.00 66.73  ? 163 ASN C CA  1 
ATOM 1063 C C   . ASN A 1 163 ? 180.854 146.899 183.225 1.00 66.73  ? 163 ASN C C   1 
ATOM 1064 O O   . ASN A 1 163 ? 179.674 147.013 182.881 1.00 66.73  ? 163 ASN C O   1 
ATOM 1065 C CB  . ASN A 1 163 ? 181.046 147.072 185.712 1.00 66.73  ? 163 ASN C CB  1 
ATOM 1066 C CG  . ASN A 1 163 ? 182.084 147.292 186.791 1.00 66.73  ? 163 ASN C CG  1 
ATOM 1067 O OD1 . ASN A 1 163 ? 182.234 146.473 187.696 1.00 66.73  ? 163 ASN C OD1 1 
ATOM 1068 N ND2 . ASN A 1 163 ? 182.812 148.397 186.697 1.00 66.73  ? 163 ASN C ND2 1 
ATOM 1069 N N   . ARG A 1 164 ? 181.699 146.074 182.628 1.00 67.62  ? 164 ARG C N   1 
ATOM 1070 C CA  . ARG A 1 164 ? 181.279 145.195 181.544 1.00 67.62  ? 164 ARG C CA  1 
ATOM 1071 C C   . ARG A 1 164 ? 180.361 144.108 182.083 1.00 67.62  ? 164 ARG C C   1 
ATOM 1072 O O   . ARG A 1 164 ? 180.743 143.390 183.014 1.00 67.62  ? 164 ARG C O   1 
ATOM 1073 C CB  . ARG A 1 164 ? 182.487 144.569 180.865 1.00 67.62  ? 164 ARG C CB  1 
ATOM 1074 C CG  . ARG A 1 164 ? 182.153 143.462 179.891 1.00 67.62  ? 164 ARG C CG  1 
ATOM 1075 C CD  . ARG A 1 164 ? 183.407 142.938 179.218 1.00 67.62  ? 164 ARG C CD  1 
ATOM 1076 N NE  . ARG A 1 164 ? 183.098 142.265 177.964 1.00 67.62  ? 164 ARG C NE  1 
ATOM 1077 C CZ  . ARG A 1 164 ? 182.887 140.960 177.856 1.00 67.62  ? 164 ARG C CZ  1 
ATOM 1078 N NH1 . ARG A 1 164 ? 183.022 140.150 178.893 1.00 67.62  ? 164 ARG C NH1 1 
ATOM 1079 N NH2 . ARG A 1 164 ? 182.542 140.453 176.678 1.00 67.62  ? 164 ARG C NH2 1 
ATOM 1080 N N   . PRO A 1 165 ? 179.154 143.964 181.538 1.00 62.96  ? 165 PRO C N   1 
ATOM 1081 C CA  . PRO A 1 165 ? 178.222 142.974 182.078 1.00 62.96  ? 165 PRO C CA  1 
ATOM 1082 C C   . PRO A 1 165 ? 178.722 141.569 181.807 1.00 62.96  ? 165 PRO C C   1 
ATOM 1083 O O   . PRO A 1 165 ? 179.337 141.293 180.776 1.00 62.96  ? 165 PRO C O   1 
ATOM 1084 C CB  . PRO A 1 165 ? 176.916 143.258 181.327 1.00 62.96  ? 165 PRO C CB  1 
ATOM 1085 C CG  . PRO A 1 165 ? 177.166 144.493 180.508 1.00 62.96  ? 165 PRO C CG  1 
ATOM 1086 C CD  . PRO A 1 165 ? 178.637 144.583 180.312 1.00 62.96  ? 165 PRO C CD  1 
ATOM 1087 N N   . GLN A 1 166 ? 178.450 140.676 182.749 1.00 74.66  ? 166 GLN C N   1 
ATOM 1088 C CA  . GLN A 1 166 ? 178.871 139.289 182.655 1.00 74.66  ? 166 GLN C CA  1 
ATOM 1089 C C   . GLN A 1 166 ? 177.629 138.413 182.627 1.00 74.66  ? 166 GLN C C   1 
ATOM 1090 O O   . GLN A 1 166 ? 176.769 138.518 183.508 1.00 74.66  ? 166 GLN C O   1 
ATOM 1091 C CB  . GLN A 1 166 ? 179.791 138.914 183.821 1.00 74.66  ? 166 GLN C CB  1 
ATOM 1092 C CG  . GLN A 1 166 ? 179.805 137.440 184.163 1.00 74.66  ? 166 GLN C CG  1 
ATOM 1093 C CD  . GLN A 1 166 ? 180.481 137.152 185.490 1.00 74.66  ? 166 GLN C CD  1 
ATOM 1094 O OE1 . GLN A 1 166 ? 180.097 137.694 186.528 1.00 74.66  ? 166 GLN C OE1 1 
ATOM 1095 N NE2 . GLN A 1 166 ? 181.499 136.300 185.462 1.00 74.66  ? 166 GLN C NE2 1 
ATOM 1096 N N   . GLU A 1 167 ? 177.524 137.578 181.598 1.00 76.88  ? 167 GLU C N   1 
ATOM 1097 C CA  . GLU A 1 167 ? 176.368 136.718 181.375 1.00 76.88  ? 167 GLU C CA  1 
ATOM 1098 C C   . GLU A 1 167 ? 176.684 135.345 181.958 1.00 76.88  ? 167 GLU C C   1 
ATOM 1099 O O   . GLU A 1 167 ? 177.592 134.659 181.479 1.00 76.88  ? 167 GLU C O   1 
ATOM 1100 C CB  . GLU A 1 167 ? 176.063 136.638 179.880 1.00 76.88  ? 167 GLU C CB  1 
ATOM 1101 C CG  . GLU A 1 167 ? 174.714 136.071 179.499 1.00 76.88  ? 167 GLU C CG  1 
ATOM 1102 C CD  . GLU A 1 167 ? 174.365 136.370 178.053 1.00 76.88  ? 167 GLU C CD  1 
ATOM 1103 O OE1 . GLU A 1 167 ? 173.394 135.786 177.533 1.00 76.88  ? 167 GLU C OE1 1 
ATOM 1104 O OE2 . GLU A 1 167 ? 175.064 137.199 177.434 1.00 76.88  ? 167 GLU C OE2 1 
ATOM 1105 N N   . ILE A 1 168 ? 175.944 134.940 182.986 1.00 73.67  ? 168 ILE C N   1 
ATOM 1106 C CA  . ILE A 1 168 ? 176.241 133.716 183.719 1.00 73.67  ? 168 ILE C CA  1 
ATOM 1107 C C   . ILE A 1 168 ? 175.161 132.690 183.407 1.00 73.67  ? 168 ILE C C   1 
ATOM 1108 O O   . ILE A 1 168 ? 173.991 132.884 183.756 1.00 73.67  ? 168 ILE C O   1 
ATOM 1109 C CB  . ILE A 1 168 ? 176.328 133.954 185.238 1.00 73.67  ? 168 ILE C CB  1 
ATOM 1110 C CG1 . ILE A 1 168 ? 177.444 134.928 185.597 1.00 73.67  ? 168 ILE C CG1 1 
ATOM 1111 C CG2 . ILE A 1 168 ? 176.615 132.664 185.961 1.00 73.67  ? 168 ILE C CG2 1 
ATOM 1112 C CD1 . ILE A 1 168 ? 176.954 136.340 185.726 1.00 73.67  ? 168 ILE C CD1 1 
ATOM 1113 N N   . GLU A 1 169 ? 175.557 131.599 182.755 1.00 80.96  ? 169 GLU C N   1 
ATOM 1114 C CA  . GLU A 1 169 ? 174.730 130.403 182.639 1.00 80.96  ? 169 GLU C CA  1 
ATOM 1115 C C   . GLU A 1 169 ? 174.956 129.586 183.907 1.00 80.96  ? 169 GLU C C   1 
ATOM 1116 O O   . GLU A 1 169 ? 175.411 130.145 184.906 1.00 80.96  ? 169 GLU C O   1 
ATOM 1117 C CB  . GLU A 1 169 ? 175.061 129.617 181.367 1.00 80.96  ? 169 GLU C CB  1 
ATOM 1118 C CG  . GLU A 1 169 ? 173.946 128.682 180.894 1.00 80.96  ? 169 GLU C CG  1 
ATOM 1119 C CD  . GLU A 1 169 ? 173.614 128.850 179.422 1.00 80.96  ? 169 GLU C CD  1 
ATOM 1120 O OE1 . GLU A 1 169 ? 172.725 128.124 178.928 1.00 80.96  ? 169 GLU C OE1 1 
ATOM 1121 O OE2 . GLU A 1 169 ? 174.231 129.712 178.761 1.00 80.96  ? 169 GLU C OE2 1 
ATOM 1122 N N   . ILE A 1 170 ? 174.609 128.297 183.904 1.00 89.00  ? 170 ILE C N   1 
ATOM 1123 C CA  . ILE A 1 170 ? 174.641 127.461 185.104 1.00 89.00  ? 170 ILE C CA  1 
ATOM 1124 C C   . ILE A 1 170 ? 175.894 127.745 185.927 1.00 89.00  ? 170 ILE C C   1 
ATOM 1125 O O   . ILE A 1 170 ? 177.019 127.701 185.416 1.00 89.00  ? 170 ILE C O   1 
ATOM 1126 C CB  . ILE A 1 170 ? 174.556 125.967 184.734 1.00 89.00  ? 170 ILE C CB  1 
ATOM 1127 C CG1 . ILE A 1 170 ? 174.838 125.083 185.954 1.00 89.00  ? 170 ILE C CG1 1 
ATOM 1128 C CG2 . ILE A 1 170 ? 175.508 125.638 183.590 1.00 89.00  ? 170 ILE C CG2 1 
ATOM 1129 C CD1 . ILE A 1 170 ? 173.885 125.303 187.117 1.00 89.00  ? 170 ILE C CD1 1 
ATOM 1130 N N   . GLY A 1 171 ? 175.695 128.053 187.208 1.00 91.44  ? 171 GLY C N   1 
ATOM 1131 C CA  . GLY A 1 171 ? 176.747 128.550 188.073 1.00 91.44  ? 171 GLY C CA  1 
ATOM 1132 C C   . GLY A 1 171 ? 176.198 129.544 189.078 1.00 91.44  ? 171 GLY C C   1 
ATOM 1133 O O   . GLY A 1 171 ? 175.334 130.358 188.737 1.00 91.44  ? 171 GLY C O   1 
ATOM 1134 N N   . GLU A 1 172 ? 176.687 129.496 190.315 1.00 89.97  ? 172 GLU C N   1 
ATOM 1135 C CA  . GLU A 1 172 ? 176.105 130.270 191.411 1.00 89.97  ? 172 GLU C CA  1 
ATOM 1136 C C   . GLU A 1 172 ? 176.389 131.751 191.203 1.00 89.97  ? 172 GLU C C   1 
ATOM 1137 O O   . GLU A 1 172 ? 177.538 132.193 191.252 1.00 89.97  ? 172 GLU C O   1 
ATOM 1138 C CB  . GLU A 1 172 ? 176.643 129.790 192.754 1.00 89.97  ? 172 GLU C CB  1 
ATOM 1139 C CG  . GLU A 1 172 ? 178.099 129.367 192.744 1.00 89.97  ? 172 GLU C CG  1 
ATOM 1140 C CD  . GLU A 1 172 ? 178.544 128.805 194.080 1.00 89.97  ? 172 GLU C CD  1 
ATOM 1141 O OE1 . GLU A 1 172 ? 179.492 129.359 194.675 1.00 89.97  ? 172 GLU C OE1 1 
ATOM 1142 O OE2 . GLU A 1 172 ? 177.941 127.812 194.538 1.00 89.97  ? 172 GLU C OE2 1 
ATOM 1143 N N   . SER A 1 173 ? 175.330 132.523 190.969 1.00 73.23  ? 173 SER C N   1 
ATOM 1144 C CA  . SER A 1 173 ? 175.422 133.970 190.855 1.00 73.23  ? 173 SER C CA  1 
ATOM 1145 C C   . SER A 1 173 ? 174.079 134.577 191.226 1.00 73.23  ? 173 SER C C   1 
ATOM 1146 O O   . SER A 1 173 ? 173.053 133.894 191.255 1.00 73.23  ? 173 SER C O   1 
ATOM 1147 C CB  . SER A 1 173 ? 175.824 134.408 189.444 1.00 73.23  ? 173 SER C CB  1 
ATOM 1148 O OG  . SER A 1 173 ? 175.083 133.695 188.472 1.00 73.23  ? 173 SER C OG  1 
ATOM 1149 N N   . GLY A 1 174 ? 174.096 135.873 191.518 1.00 65.85  ? 174 GLY C N   1 
ATOM 1150 C CA  . GLY A 1 174 ? 172.875 136.578 191.848 1.00 65.85  ? 174 GLY C CA  1 
ATOM 1151 C C   . GLY A 1 174 ? 173.101 138.035 192.186 1.00 65.85  ? 174 GLY C C   1 
ATOM 1152 O O   . GLY A 1 174 ? 174.222 138.433 192.517 1.00 65.85  ? 174 GLY C O   1 
ATOM 1153 N N   . PHE A 1 175 ? 172.047 138.841 192.109 1.00 55.10  ? 175 PHE C N   1 
ATOM 1154 C CA  . PHE A 1 175 ? 172.135 140.259 192.416 1.00 55.10  ? 175 PHE C CA  1 
ATOM 1155 C C   . PHE A 1 175 ? 170.962 140.671 193.290 1.00 55.10  ? 175 PHE C C   1 
ATOM 1156 O O   . PHE A 1 175 ? 169.911 140.026 193.292 1.00 55.10  ? 175 PHE C O   1 
ATOM 1157 C CB  . PHE A 1 175 ? 172.146 141.128 191.151 1.00 55.10  ? 175 PHE C CB  1 
ATOM 1158 C CG  . PHE A 1 175 ? 170.948 140.936 190.266 1.00 55.10  ? 175 PHE C CG  1 
ATOM 1159 C CD1 . PHE A 1 175 ? 170.815 139.805 189.482 1.00 55.10  ? 175 PHE C CD1 1 
ATOM 1160 C CD2 . PHE A 1 175 ? 169.952 141.893 190.219 1.00 55.10  ? 175 PHE C CD2 1 
ATOM 1161 C CE1 . PHE A 1 175 ? 169.714 139.636 188.672 1.00 55.10  ? 175 PHE C CE1 1 
ATOM 1162 C CE2 . PHE A 1 175 ? 168.850 141.725 189.412 1.00 55.10  ? 175 PHE C CE2 1 
ATOM 1163 C CZ  . PHE A 1 175 ? 168.734 140.599 188.635 1.00 55.10  ? 175 PHE C CZ  1 
ATOM 1164 N N   . ALA A 1 176 ? 171.159 141.752 194.038 1.00 56.69  ? 176 ALA C N   1 
ATOM 1165 C CA  . ALA A 1 176 ? 170.105 142.372 194.828 1.00 56.69  ? 176 ALA C CA  1 
ATOM 1166 C C   . ALA A 1 176 ? 170.047 143.851 194.482 1.00 56.69  ? 176 ALA C C   1 
ATOM 1167 O O   . ALA A 1 176 ? 171.081 144.526 194.461 1.00 56.69  ? 176 ALA C O   1 
ATOM 1168 C CB  . ALA A 1 176 ? 170.345 142.181 196.329 1.00 56.69  ? 176 ALA C CB  1 
ATOM 1169 N N   . LEU A 1 177 ? 168.846 144.350 194.207 1.00 47.40  ? 177 LEU C N   1 
ATOM 1170 C CA  . LEU A 1 177 ? 168.634 145.739 193.823 1.00 47.40  ? 177 LEU C CA  1 
ATOM 1171 C C   . LEU A 1 177 ? 168.002 146.481 194.992 1.00 47.40  ? 177 LEU C C   1 
ATOM 1172 O O   . LEU A 1 177 ? 166.920 146.107 195.452 1.00 47.40  ? 177 LEU C O   1 
ATOM 1173 C CB  . LEU A 1 177 ? 167.743 145.832 192.585 1.00 47.40  ? 177 LEU C CB  1 
ATOM 1174 C CG  . LEU A 1 177 ? 168.355 145.347 191.274 1.00 47.40  ? 177 LEU C CG  1 
ATOM 1175 C CD1 . LEU A 1 177 ? 167.366 145.498 190.135 1.00 47.40  ? 177 LEU C CD1 1 
ATOM 1176 C CD2 . LEU A 1 177 ? 169.625 146.115 190.983 1.00 47.40  ? 177 LEU C CD2 1 
ATOM 1177 N N   . LEU A 1 178 ? 168.666 147.534 195.459 1.00 49.89  ? 178 LEU C N   1 
ATOM 1178 C CA  . LEU A 1 178 ? 168.194 148.325 196.590 1.00 49.89  ? 178 LEU C CA  1 
ATOM 1179 C C   . LEU A 1 178 ? 167.588 149.621 196.064 1.00 49.89  ? 178 LEU C C   1 
ATOM 1180 O O   . LEU A 1 178 ? 168.305 150.482 195.545 1.00 49.89  ? 178 LEU C O   1 
ATOM 1181 C CB  . LEU A 1 178 ? 169.331 148.604 197.568 1.00 49.89  ? 178 LEU C CB  1 
ATOM 1182 C CG  . LEU A 1 178 ? 170.151 147.378 197.967 1.00 49.89  ? 178 LEU C CG  1 
ATOM 1183 C CD1 . LEU A 1 178 ? 171.266 147.760 198.922 1.00 49.89  ? 178 LEU C CD1 1 
ATOM 1184 C CD2 . LEU A 1 178 ? 169.254 146.320 198.585 1.00 49.89  ? 178 LEU C CD2 1 
ATOM 1185 N N   . PHE A 1 179 ? 166.268 149.755 196.201 1.00 53.61  ? 179 PHE C N   1 
ATOM 1186 C CA  . PHE A 1 179 ? 165.566 150.960 195.783 1.00 53.61  ? 179 PHE C CA  1 
ATOM 1187 C C   . PHE A 1 179 ? 165.333 151.855 196.987 1.00 53.61  ? 179 PHE C C   1 
ATOM 1188 O O   . PHE A 1 179 ? 164.630 151.444 197.924 1.00 53.61  ? 179 PHE C O   1 
ATOM 1189 C CB  . PHE A 1 179 ? 164.237 150.608 195.125 1.00 53.61  ? 179 PHE C CB  1 
ATOM 1190 C CG  . PHE A 1 179 ? 164.375 149.889 193.814 1.00 53.61  ? 179 PHE C CG  1 
ATOM 1191 C CD1 . PHE A 1 179 ? 165.218 150.373 192.830 1.00 53.61  ? 179 PHE C CD1 1 
ATOM 1192 C CD2 . PHE A 1 179 ? 163.659 148.733 193.564 1.00 53.61  ? 179 PHE C CD2 1 
ATOM 1193 C CE1 . PHE A 1 179 ? 165.345 149.714 191.624 1.00 53.61  ? 179 PHE C CE1 1 
ATOM 1194 C CE2 . PHE A 1 179 ? 163.782 148.072 192.360 1.00 53.61  ? 179 PHE C CE2 1 
ATOM 1195 C CZ  . PHE A 1 179 ? 164.625 148.563 191.389 1.00 53.61  ? 179 PHE C CZ  1 
ATOM 1196 N N   . PRO A 1 180 ? 165.887 153.064 197.017 1.00 62.59  ? 180 PRO C N   1 
ATOM 1197 C CA  . PRO A 1 180 ? 165.669 153.947 198.167 1.00 62.59  ? 180 PRO C CA  1 
ATOM 1198 C C   . PRO A 1 180 ? 164.351 154.694 198.077 1.00 62.59  ? 180 PRO C C   1 
ATOM 1199 O O   . PRO A 1 180 ? 163.608 154.537 197.104 1.00 62.59  ? 180 PRO C O   1 
ATOM 1200 C CB  . PRO A 1 180 ? 166.861 154.904 198.091 1.00 62.59  ? 180 PRO C CB  1 
ATOM 1201 C CG  . PRO A 1 180 ? 167.120 155.020 196.624 1.00 62.59  ? 180 PRO C CG  1 
ATOM 1202 C CD  . PRO A 1 180 ? 166.756 153.686 196.003 1.00 62.59  ? 180 PRO C CD  1 
ATOM 1203 N N   . GLN A 1 181 ? 164.052 155.511 199.084 1.00 79.04  ? 181 GLN C N   1 
ATOM 1204 C CA  . GLN A 1 181 ? 162.835 156.317 199.072 1.00 79.04  ? 181 GLN C CA  1 
ATOM 1205 C C   . GLN A 1 181 ? 163.002 157.469 198.090 1.00 79.04  ? 181 GLN C C   1 
ATOM 1206 O O   . GLN A 1 181 ? 163.786 158.392 198.329 1.00 79.04  ? 181 GLN C O   1 
ATOM 1207 C CB  . GLN A 1 181 ? 162.525 156.832 200.475 1.00 79.04  ? 181 GLN C CB  1 
ATOM 1208 C CG  . GLN A 1 181 ? 161.179 157.542 200.613 1.00 79.04  ? 181 GLN C CG  1 
ATOM 1209 C CD  . GLN A 1 181 ? 159.983 156.602 200.560 1.00 79.04  ? 181 GLN C CD  1 
ATOM 1210 O OE1 . GLN A 1 181 ? 159.919 155.691 199.733 1.00 79.04  ? 181 GLN C OE1 1 
ATOM 1211 N NE2 . GLN A 1 181 ? 159.025 156.824 201.452 1.00 79.04  ? 181 GLN C NE2 1 
ATOM 1212 N N   . ILE A 1 182 ? 162.262 157.418 196.987 1.00 77.35  ? 182 ILE C N   1 
ATOM 1213 C CA  . ILE A 1 182 ? 162.338 158.412 195.925 1.00 77.35  ? 182 ILE C CA  1 
ATOM 1214 C C   . ILE A 1 182 ? 161.022 159.177 195.888 1.00 77.35  ? 182 ILE C C   1 
ATOM 1215 O O   . ILE A 1 182 ? 159.943 158.573 195.897 1.00 77.35  ? 182 ILE C O   1 
ATOM 1216 C CB  . ILE A 1 182 ? 162.654 157.756 194.568 1.00 77.35  ? 182 ILE C CB  1 
ATOM 1217 C CG1 . ILE A 1 182 ? 162.565 158.776 193.430 1.00 77.35  ? 182 ILE C CG1 1 
ATOM 1218 C CG2 . ILE A 1 182 ? 161.761 156.547 194.329 1.00 77.35  ? 182 ILE C CG2 1 
ATOM 1219 C CD1 . ILE A 1 182 ? 163.611 159.858 193.493 1.00 77.35  ? 182 ILE C CD1 1 
ATOM 1220 N N   . GLU A 1 183 ? 161.114 160.505 195.865 1.00 78.12  ? 183 GLU C N   1 
ATOM 1221 C CA  . GLU A 1 183 ? 159.924 161.344 195.923 1.00 78.12  ? 183 GLU C CA  1 
ATOM 1222 C C   . GLU A 1 183 ? 159.117 161.229 194.635 1.00 78.12  ? 183 GLU C C   1 
ATOM 1223 O O   . GLU A 1 183 ? 159.659 161.362 193.534 1.00 78.12  ? 183 GLU C O   1 
ATOM 1224 C CB  . GLU A 1 183 ? 160.319 162.800 196.168 1.00 78.12  ? 183 GLU C CB  1 
ATOM 1225 C CG  . GLU A 1 183 ? 160.639 163.125 197.618 1.00 78.12  ? 183 GLU C CG  1 
ATOM 1226 C CD  . GLU A 1 183 ? 159.573 163.979 198.274 1.00 78.12  ? 183 GLU C CD  1 
ATOM 1227 O OE1 . GLU A 1 183 ? 159.798 164.445 199.410 1.00 78.12  ? 183 GLU C OE1 1 
ATOM 1228 O OE2 . GLU A 1 183 ? 158.510 164.187 197.652 1.00 78.12  ? 183 GLU C OE2 1 
ATOM 1229 N N   . GLY A 1 184 ? 157.817 160.983 194.778 1.00 66.14  ? 184 GLY C N   1 
ATOM 1230 C CA  . GLY A 1 184 ? 156.911 160.938 193.651 1.00 66.14  ? 184 GLY C CA  1 
ATOM 1231 C C   . GLY A 1 184 ? 156.818 159.608 192.937 1.00 66.14  ? 184 GLY C C   1 
ATOM 1232 O O   . GLY A 1 184 ? 155.995 159.475 192.023 1.00 66.14  ? 184 GLY C O   1 
ATOM 1233 N N   . ILE A 1 185 ? 157.629 158.623 193.313 1.00 58.00  ? 185 ILE C N   1 
ATOM 1234 C CA  . ILE A 1 185 ? 157.611 157.299 192.701 1.00 58.00  ? 185 ILE C CA  1 
ATOM 1235 C C   . ILE A 1 185 ? 157.265 156.289 193.784 1.00 58.00  ? 185 ILE C C   1 
ATOM 1236 O O   . ILE A 1 185 ? 157.903 156.266 194.843 1.00 58.00  ? 185 ILE C O   1 
ATOM 1237 C CB  . ILE A 1 185 ? 158.958 156.948 192.039 1.00 58.00  ? 185 ILE C CB  1 
ATOM 1238 C CG1 . ILE A 1 185 ? 159.062 157.535 190.627 1.00 58.00  ? 185 ILE C CG1 1 
ATOM 1239 C CG2 . ILE A 1 185 ? 159.150 155.442 191.982 1.00 58.00  ? 185 ILE C CG2 1 
ATOM 1240 C CD1 . ILE A 1 185 ? 159.106 159.046 190.557 1.00 58.00  ? 185 ILE C CD1 1 
ATOM 1241 N N   . LYS A 1 186 ? 156.255 155.463 193.525 1.00 46.40  ? 186 LYS C N   1 
ATOM 1242 C CA  . LYS A 1 186 ? 155.792 154.477 194.488 1.00 46.40  ? 186 LYS C CA  1 
ATOM 1243 C C   . LYS A 1 186 ? 155.767 153.101 193.838 1.00 46.40  ? 186 LYS C C   1 
ATOM 1244 O O   . LYS A 1 186 ? 155.187 152.923 192.762 1.00 46.40  ? 186 LYS C O   1 
ATOM 1245 C CB  . LYS A 1 186 ? 154.404 154.853 195.024 1.00 46.40  ? 186 LYS C CB  1 
ATOM 1246 C CG  . LYS A 1 186 ? 153.966 154.073 196.252 1.00 46.40  ? 186 LYS C CG  1 
ATOM 1247 C CD  . LYS A 1 186 ? 152.839 153.113 195.930 1.00 46.40  ? 186 LYS C CD  1 
ATOM 1248 C CE  . LYS A 1 186 ? 152.260 152.487 197.187 1.00 46.40  ? 186 LYS C CE  1 
ATOM 1249 N NZ  . LYS A 1 186 ? 150.858 152.032 196.979 1.00 46.40  ? 186 LYS C NZ  1 
ATOM 1250 N N   . ILE A 1 187 ? 156.400 152.133 194.497 1.00 42.17  ? 187 ILE C N   1 
ATOM 1251 C CA  . ILE A 1 187 ? 156.552 150.775 193.984 1.00 42.17  ? 187 ILE C CA  1 
ATOM 1252 C C   . ILE A 1 187 ? 155.890 149.825 194.969 1.00 42.17  ? 187 ILE C C   1 
ATOM 1253 O O   . ILE A 1 187 ? 156.142 149.908 196.177 1.00 42.17  ? 187 ILE C O   1 
ATOM 1254 C CB  . ILE A 1 187 ? 158.029 150.398 193.787 1.00 42.17  ? 187 ILE C CB  1 
ATOM 1255 C CG1 . ILE A 1 187 ? 158.717 151.406 192.867 1.00 42.17  ? 187 ILE C CG1 1 
ATOM 1256 C CG2 . ILE A 1 187 ? 158.150 148.993 193.234 1.00 42.17  ? 187 ILE C CG2 1 
ATOM 1257 C CD1 . ILE A 1 187 ? 160.202 151.538 193.113 1.00 42.17  ? 187 ILE C CD1 1 
ATOM 1258 N N   . GLN A 1 188 ? 155.045 148.924 194.461 1.00 44.10  ? 188 GLN C N   1 
ATOM 1259 C CA  . GLN A 1 188 ? 154.308 148.015 195.326 1.00 44.10  ? 188 GLN C CA  1 
ATOM 1260 C C   . GLN A 1 188 ? 154.290 146.621 194.707 1.00 44.10  ? 188 GLN C C   1 
ATOM 1261 O O   . GLN A 1 188 ? 153.848 146.461 193.556 1.00 44.10  ? 188 GLN C O   1 
ATOM 1262 C CB  . GLN A 1 188 ? 152.881 148.517 195.553 1.00 44.10  ? 188 GLN C CB  1 
ATOM 1263 C CG  . GLN A 1 188 ? 152.142 148.891 194.280 1.00 44.10  ? 188 GLN C CG  1 
ATOM 1264 C CD  . GLN A 1 188 ? 152.219 150.365 193.951 1.00 44.10  ? 188 GLN C CD  1 
ATOM 1265 O OE1 . GLN A 1 188 ? 153.306 150.929 193.840 1.00 44.10  ? 188 GLN C OE1 1 
ATOM 1266 N NE2 . GLN A 1 188 ? 151.064 151.000 193.796 1.00 44.10  ? 188 GLN C NE2 1 
ATOM 1267 N N   . PRO A 1 189 ? 154.764 145.605 195.422 1.00 47.64  ? 189 PRO C N   1 
ATOM 1268 C CA  . PRO A 1 189 ? 154.695 144.240 194.894 1.00 47.64  ? 189 PRO C CA  1 
ATOM 1269 C C   . PRO A 1 189 ? 153.259 143.744 194.824 1.00 47.64  ? 189 PRO C C   1 
ATOM 1270 O O   . PRO A 1 189 ? 152.348 144.299 195.442 1.00 47.64  ? 189 PRO C O   1 
ATOM 1271 C CB  . PRO A 1 189 ? 155.511 143.427 195.903 1.00 47.64  ? 189 PRO C CB  1 
ATOM 1272 C CG  . PRO A 1 189 ? 156.426 144.418 196.533 1.00 47.64  ? 189 PRO C CG  1 
ATOM 1273 C CD  . PRO A 1 189 ? 155.651 145.701 196.591 1.00 47.64  ? 189 PRO C CD  1 
ATOM 1274 N N   . PHE A 1 190 ? 153.063 142.679 194.050 1.00 50.55  ? 190 PHE C N   1 
ATOM 1275 C CA  . PHE A 1 190 ? 151.761 142.038 193.946 1.00 50.55  ? 190 PHE C CA  1 
ATOM 1276 C C   . PHE A 1 190 ? 151.962 140.542 193.764 1.00 50.55  ? 190 PHE C C   1 
ATOM 1277 O O   . PHE A 1 190 ? 153.011 140.104 193.285 1.00 50.55  ? 190 PHE C O   1 
ATOM 1278 C CB  . PHE A 1 190 ? 150.934 142.621 192.793 1.00 50.55  ? 190 PHE C CB  1 
ATOM 1279 C CG  . PHE A 1 190 ? 151.492 142.334 191.427 1.00 50.55  ? 190 PHE C CG  1 
ATOM 1280 C CD1 . PHE A 1 190 ? 151.112 141.201 190.728 1.00 50.55  ? 190 PHE C CD1 1 
ATOM 1281 C CD2 . PHE A 1 190 ? 152.391 143.204 190.837 1.00 50.55  ? 190 PHE C CD2 1 
ATOM 1282 C CE1 . PHE A 1 190 ? 151.621 140.941 189.472 1.00 50.55  ? 190 PHE C CE1 1 
ATOM 1283 C CE2 . PHE A 1 190 ? 152.903 142.948 189.582 1.00 50.55  ? 190 PHE C CE2 1 
ATOM 1284 C CZ  . PHE A 1 190 ? 152.517 141.815 188.900 1.00 50.55  ? 190 PHE C CZ  1 
ATOM 1285 N N   . HIS A 1 191 ? 150.951 139.766 194.146 1.00 62.07  ? 191 HIS C N   1 
ATOM 1286 C CA  . HIS A 1 191 ? 151.042 138.309 194.102 1.00 62.07  ? 191 HIS C CA  1 
ATOM 1287 C C   . HIS A 1 191 ? 149.639 137.740 193.955 1.00 62.07  ? 191 HIS C C   1 
ATOM 1288 O O   . HIS A 1 191 ? 148.769 138.012 194.787 1.00 62.07  ? 191 HIS C O   1 
ATOM 1289 C CB  . HIS A 1 191 ? 151.723 137.768 195.356 1.00 62.07  ? 191 HIS C CB  1 
ATOM 1290 C CG  . HIS A 1 191 ? 151.731 136.274 195.448 1.00 62.07  ? 191 HIS C CG  1 
ATOM 1291 N ND1 . HIS A 1 191 ? 151.802 135.605 196.650 1.00 62.07  ? 191 HIS C ND1 1 
ATOM 1292 C CD2 . HIS A 1 191 ? 151.668 135.320 194.490 1.00 62.07  ? 191 HIS C CD2 1 
ATOM 1293 C CE1 . HIS A 1 191 ? 151.789 134.303 196.428 1.00 62.07  ? 191 HIS C CE1 1 
ATOM 1294 N NE2 . HIS A 1 191 ? 151.707 134.103 195.125 1.00 62.07  ? 191 HIS C NE2 1 
ATOM 1295 N N   . PHE A 1 192 ? 149.423 136.957 192.903 1.00 66.05  ? 192 PHE C N   1 
ATOM 1296 C CA  . PHE A 1 192 ? 148.164 136.254 192.680 1.00 66.05  ? 192 PHE C CA  1 
ATOM 1297 C C   . PHE A 1 192 ? 148.468 134.760 192.675 1.00 66.05  ? 192 PHE C C   1 
ATOM 1298 O O   . PHE A 1 192 ? 148.977 134.224 191.687 1.00 66.05  ? 192 PHE C O   1 
ATOM 1299 C CB  . PHE A 1 192 ? 147.510 136.694 191.376 1.00 66.05  ? 192 PHE C CB  1 
ATOM 1300 C CG  . PHE A 1 192 ? 147.414 138.180 191.221 1.00 66.05  ? 192 PHE C CG  1 
ATOM 1301 C CD1 . PHE A 1 192 ? 146.812 138.952 192.195 1.00 66.05  ? 192 PHE C CD1 1 
ATOM 1302 C CD2 . PHE A 1 192 ? 147.917 138.803 190.095 1.00 66.05  ? 192 PHE C CD2 1 
ATOM 1303 C CE1 . PHE A 1 192 ? 146.723 140.321 192.053 1.00 66.05  ? 192 PHE C CE1 1 
ATOM 1304 C CE2 . PHE A 1 192 ? 147.829 140.170 189.947 1.00 66.05  ? 192 PHE C CE2 1 
ATOM 1305 C CZ  . PHE A 1 192 ? 147.230 140.930 190.927 1.00 66.05  ? 192 PHE C CZ  1 
ATOM 1306 N N   . ILE A 1 193 ? 148.157 134.091 193.782 1.00 70.55  ? 193 ILE C N   1 
ATOM 1307 C CA  . ILE A 1 193 ? 148.390 132.659 193.911 1.00 70.55  ? 193 ILE C CA  1 
ATOM 1308 C C   . ILE A 1 193 ? 147.393 131.927 193.022 1.00 70.55  ? 193 ILE C C   1 
ATOM 1309 O O   . ILE A 1 193 ? 146.312 132.448 192.729 1.00 70.55  ? 193 ILE C O   1 
ATOM 1310 C CB  . ILE A 1 193 ? 148.273 132.213 195.381 1.00 70.55  ? 193 ILE C CB  1 
ATOM 1311 C CG1 . ILE A 1 193 ? 148.851 130.811 195.573 1.00 70.55  ? 193 ILE C CG1 1 
ATOM 1312 C CG2 . ILE A 1 193 ? 146.826 132.268 195.846 1.00 70.55  ? 193 ILE C CG2 1 
ATOM 1313 C CD1 . ILE A 1 193 ? 150.260 130.668 195.054 1.00 70.55  ? 193 ILE C CD1 1 
ATOM 1314 N N   . LYS A 1 194 ? 147.746 130.727 192.573 1.00 88.27  ? 194 LYS C N   1 
ATOM 1315 C CA  . LYS A 1 194 ? 146.838 129.924 191.773 1.00 88.27  ? 194 LYS C CA  1 
ATOM 1316 C C   . LYS A 1 194 ? 145.828 129.244 192.702 1.00 88.27  ? 194 LYS C C   1 
ATOM 1317 O O   . LYS A 1 194 ? 145.887 129.400 193.927 1.00 88.27  ? 194 LYS C O   1 
ATOM 1318 C CB  . LYS A 1 194 ? 147.636 128.924 190.923 1.00 88.27  ? 194 LYS C CB  1 
ATOM 1319 C CG  . LYS A 1 194 ? 146.826 128.266 189.809 1.00 88.27  ? 194 LYS C CG  1 
ATOM 1320 C CD  . LYS A 1 194 ? 147.563 127.111 189.165 1.00 88.27  ? 194 LYS C CD  1 
ATOM 1321 C CE  . LYS A 1 194 ? 146.854 126.651 187.904 1.00 88.27  ? 194 LYS C CE  1 
ATOM 1322 N NZ  . LYS A 1 194 ? 146.103 127.757 187.250 1.00 88.27  ? 194 LYS C NZ  1 
ATOM 1323 N N   . ASP A 1 195 ? 144.902 128.482 192.130 1.00 109.67 ? 195 ASP C N   1 
ATOM 1324 C CA  . ASP A 1 195 ? 143.828 127.854 192.883 1.00 109.67 ? 195 ASP C CA  1 
ATOM 1325 C C   . ASP A 1 195 ? 143.589 126.432 192.394 1.00 109.67 ? 195 ASP C C   1 
ATOM 1326 O O   . ASP A 1 195 ? 143.806 126.136 191.212 1.00 109.67 ? 195 ASP C O   1 
ATOM 1327 C CB  . ASP A 1 195 ? 142.547 128.679 192.752 1.00 109.67 ? 195 ASP C CB  1 
ATOM 1328 C CG  . ASP A 1 195 ? 142.223 129.026 191.307 1.00 109.67 ? 195 ASP C CG  1 
ATOM 1329 O OD1 . ASP A 1 195 ? 142.999 128.637 190.408 1.00 109.67 ? 195 ASP C OD1 1 
ATOM 1330 O OD2 . ASP A 1 195 ? 141.195 129.689 191.064 1.00 109.67 ? 195 ASP C OD2 1 
ATOM 1331 N N   . PRO A 1 196 ? 143.161 125.525 193.265 1.00 117.11 ? 196 PRO C N   1 
ATOM 1332 C CA  . PRO A 1 196 ? 142.668 124.229 192.785 1.00 117.11 ? 196 PRO C CA  1 
ATOM 1333 C C   . PRO A 1 196 ? 141.375 124.409 192.011 1.00 117.11 ? 196 PRO C C   1 
ATOM 1334 O O   . PRO A 1 196 ? 141.211 123.875 190.910 1.00 117.11 ? 196 PRO C O   1 
ATOM 1335 C CB  . PRO A 1 196 ? 142.456 123.428 194.077 1.00 117.11 ? 196 PRO C CB  1 
ATOM 1336 C CG  . PRO A 1 196 ? 143.296 124.126 195.105 1.00 117.11 ? 196 PRO C CG  1 
ATOM 1337 C CD  . PRO A 1 196 ? 143.238 125.574 194.733 1.00 117.11 ? 196 PRO C CD  1 
ATOM 1338 N N   . LYS A 1 197 ? 140.452 125.177 192.590 1.00 127.36 ? 197 LYS C N   1 
ATOM 1339 C CA  . LYS A 1 197 ? 139.178 125.506 191.953 1.00 127.36 ? 197 LYS C CA  1 
ATOM 1340 C C   . LYS A 1 197 ? 138.631 126.768 192.612 1.00 127.36 ? 197 LYS C C   1 
ATOM 1341 O O   . LYS A 1 197 ? 138.238 126.752 193.782 1.00 127.36 ? 197 LYS C O   1 
ATOM 1342 C CB  . LYS A 1 197 ? 138.196 124.347 192.072 1.00 127.36 ? 197 LYS C CB  1 
ATOM 1343 C CG  . LYS A 1 197 ? 138.288 123.588 193.386 1.00 127.36 ? 197 LYS C CG  1 
ATOM 1344 C CD  . LYS A 1 197 ? 137.032 122.776 193.639 1.00 127.36 ? 197 LYS C CD  1 
ATOM 1345 C CE  . LYS A 1 197 ? 135.992 123.599 194.381 1.00 127.36 ? 197 LYS C CE  1 
ATOM 1346 N NZ  . LYS A 1 197 ? 136.527 124.152 195.656 1.00 127.36 ? 197 LYS C NZ  1 
ATOM 1347 N N   . ASN A 1 198 ? 138.607 127.867 191.862 1.00 129.54 ? 198 ASN C N   1 
ATOM 1348 C CA  . ASN A 1 198 ? 138.094 129.135 192.363 1.00 129.54 ? 198 ASN C CA  1 
ATOM 1349 C C   . ASN A 1 198 ? 137.811 130.052 191.179 1.00 129.54 ? 198 ASN C C   1 
ATOM 1350 O O   . ASN A 1 198 ? 137.829 129.630 190.020 1.00 129.54 ? 198 ASN C O   1 
ATOM 1351 C CB  . ASN A 1 198 ? 139.078 129.783 193.343 1.00 129.54 ? 198 ASN C CB  1 
ATOM 1352 C CG  . ASN A 1 198 ? 138.532 129.858 194.754 1.00 129.54 ? 198 ASN C CG  1 
ATOM 1353 O OD1 . ASN A 1 198 ? 137.322 129.795 194.967 1.00 129.54 ? 198 ASN C OD1 1 
ATOM 1354 N ND2 . ASN A 1 198 ? 139.424 129.996 195.728 1.00 129.54 ? 198 ASN C ND2 1 
ATOM 1355 N N   . LEU A 1 199 ? 137.549 131.323 191.483 1.00 120.98 ? 199 LEU C N   1 
ATOM 1356 C CA  . LEU A 1 199 ? 137.356 132.336 190.451 1.00 120.98 ? 199 LEU C CA  1 
ATOM 1357 C C   . LEU A 1 199 ? 138.693 132.693 189.817 1.00 120.98 ? 199 LEU C C   1 
ATOM 1358 O O   . LEU A 1 199 ? 139.697 132.019 190.066 1.00 120.98 ? 199 LEU C O   1 
ATOM 1359 C CB  . LEU A 1 199 ? 136.695 133.583 191.040 1.00 120.98 ? 199 LEU C CB  1 
ATOM 1360 C CG  . LEU A 1 199 ? 137.397 134.205 192.251 1.00 120.98 ? 199 LEU C CG  1 
ATOM 1361 C CD1 . LEU A 1 199 ? 138.207 135.435 191.845 1.00 120.98 ? 199 LEU C CD1 1 
ATOM 1362 C CD2 . LEU A 1 199 ? 136.388 134.556 193.331 1.00 120.98 ? 199 LEU C CD2 1 
ATOM 1363 N N   . THR A 1 200 ? 138.728 133.740 188.993 1.00 114.57 ? 200 THR C N   1 
ATOM 1364 C CA  . THR A 1 200 ? 140.015 134.151 188.449 1.00 114.57 ? 200 THR C CA  1 
ATOM 1365 C C   . THR A 1 200 ? 140.584 135.334 189.218 1.00 114.57 ? 200 THR C C   1 
ATOM 1366 O O   . THR A 1 200 ? 141.538 135.174 189.980 1.00 114.57 ? 200 THR C O   1 
ATOM 1367 C CB  . THR A 1 200 ? 139.882 134.529 186.974 1.00 114.57 ? 200 THR C CB  1 
ATOM 1368 O OG1 . THR A 1 200 ? 139.065 135.701 186.852 1.00 114.57 ? 200 THR C OG1 1 
ATOM 1369 C CG2 . THR A 1 200 ? 139.249 133.395 186.192 1.00 114.57 ? 200 THR C CG2 1 
ATOM 1370 N N   . LEU A 1 201 ? 139.944 136.494 189.079 1.00 104.16 ? 201 LEU C N   1 
ATOM 1371 C CA  . LEU A 1 201 ? 140.336 137.749 189.725 1.00 104.16 ? 201 LEU C CA  1 
ATOM 1372 C C   . LEU A 1 201 ? 139.140 138.675 189.603 1.00 104.16 ? 201 LEU C C   1 
ATOM 1373 O O   . LEU A 1 201 ? 138.832 139.119 188.493 1.00 104.16 ? 201 LEU C O   1 
ATOM 1374 C CB  . LEU A 1 201 ? 141.567 138.359 189.031 1.00 104.16 ? 201 LEU C CB  1 
ATOM 1375 C CG  . LEU A 1 201 ? 143.013 137.872 189.190 1.00 104.16 ? 201 LEU C CG  1 
ATOM 1376 C CD1 . LEU A 1 201 ? 143.955 139.023 188.999 1.00 104.16 ? 201 LEU C CD1 1 
ATOM 1377 C CD2 . LEU A 1 201 ? 143.250 137.350 190.587 1.00 104.16 ? 201 LEU C CD2 1 
ATOM 1378 N N   . GLU A 1 202 ? 138.456 138.965 190.709 1.00 102.18 ? 202 GLU C N   1 
ATOM 1379 C CA  . GLU A 1 202 ? 137.187 139.658 190.521 1.00 102.18 ? 202 GLU C CA  1 
ATOM 1380 C C   . GLU A 1 202 ? 137.411 141.095 190.039 1.00 102.18 ? 202 GLU C C   1 
ATOM 1381 O O   . GLU A 1 202 ? 137.195 141.375 188.856 1.00 102.18 ? 202 GLU C O   1 
ATOM 1382 C CB  . GLU A 1 202 ? 136.340 139.557 191.802 1.00 102.18 ? 202 GLU C CB  1 
ATOM 1383 C CG  . GLU A 1 202 ? 135.583 140.793 192.252 1.00 102.18 ? 202 GLU C CG  1 
ATOM 1384 C CD  . GLU A 1 202 ? 134.942 140.605 193.604 1.00 102.18 ? 202 GLU C CD  1 
ATOM 1385 O OE1 . GLU A 1 202 ? 135.355 141.283 194.566 1.00 102.18 ? 202 GLU C OE1 1 
ATOM 1386 O OE2 . GLU A 1 202 ? 134.008 139.783 193.698 1.00 102.18 ? 202 GLU C OE2 1 
ATOM 1387 N N   . ARG A 1 203 ? 137.848 142.014 190.905 1.00 89.68  ? 203 ARG C N   1 
ATOM 1388 C CA  . ARG A 1 203 ? 138.417 143.269 190.429 1.00 89.68  ? 203 ARG C CA  1 
ATOM 1389 C C   . ARG A 1 203 ? 139.460 143.833 191.387 1.00 89.68  ? 203 ARG C C   1 
ATOM 1390 O O   . ARG A 1 203 ? 140.382 144.542 190.970 1.00 89.68  ? 203 ARG C O   1 
ATOM 1391 C CB  . ARG A 1 203 ? 137.319 144.307 190.192 1.00 89.68  ? 203 ARG C CB  1 
ATOM 1392 C CG  . ARG A 1 203 ? 137.831 145.570 189.524 1.00 89.68  ? 203 ARG C CG  1 
ATOM 1393 C CD  . ARG A 1 203 ? 137.004 146.779 189.906 1.00 89.68  ? 203 ARG C CD  1 
ATOM 1394 N NE  . ARG A 1 203 ? 137.520 148.015 189.326 1.00 89.68  ? 203 ARG C NE  1 
ATOM 1395 C CZ  . ARG A 1 203 ? 137.427 148.351 188.046 1.00 89.68  ? 203 ARG C CZ  1 
ATOM 1396 N NH1 . ARG A 1 203 ? 136.848 147.556 187.162 1.00 89.68  ? 203 ARG C NH1 1 
ATOM 1397 N NH2 . ARG A 1 203 ? 137.925 149.516 187.644 1.00 89.68  ? 203 ARG C NH2 1 
ATOM 1398 N N   . HIS A 1 204 ? 139.326 143.507 192.676 1.00 89.81  ? 204 HIS C N   1 
ATOM 1399 C CA  . HIS A 1 204 ? 139.918 144.345 193.714 1.00 89.81  ? 204 HIS C CA  1 
ATOM 1400 C C   . HIS A 1 204 ? 141.423 144.181 193.828 1.00 89.81  ? 204 HIS C C   1 
ATOM 1401 O O   . HIS A 1 204 ? 142.104 145.132 194.226 1.00 89.81  ? 204 HIS C O   1 
ATOM 1402 C CB  . HIS A 1 204 ? 139.292 144.051 195.082 1.00 89.81  ? 204 HIS C CB  1 
ATOM 1403 C CG  . HIS A 1 204 ? 139.036 142.599 195.343 1.00 89.81  ? 204 HIS C CG  1 
ATOM 1404 N ND1 . HIS A 1 204 ? 138.170 141.837 194.586 1.00 89.81  ? 204 HIS C ND1 1 
ATOM 1405 C CD2 . HIS A 1 204 ? 139.550 141.765 196.277 1.00 89.81  ? 204 HIS C CD2 1 
ATOM 1406 C CE1 . HIS A 1 204 ? 138.158 140.600 195.048 1.00 89.81  ? 204 HIS C CE1 1 
ATOM 1407 N NE2 . HIS A 1 204 ? 138.983 140.530 196.076 1.00 89.81  ? 204 HIS C NE2 1 
ATOM 1408 N N   . GLN A 1 205 ? 141.954 143.004 193.510 1.00 84.95  ? 205 GLN C N   1 
ATOM 1409 C CA  . GLN A 1 205 ? 143.389 142.760 193.585 1.00 84.95  ? 205 GLN C CA  1 
ATOM 1410 C C   . GLN A 1 205 ? 144.155 143.661 192.621 1.00 84.95  ? 205 GLN C C   1 
ATOM 1411 O O   . GLN A 1 205 ? 145.327 143.974 192.851 1.00 84.95  ? 205 GLN C O   1 
ATOM 1412 C CB  . GLN A 1 205 ? 143.660 141.279 193.319 1.00 84.95  ? 205 GLN C CB  1 
ATOM 1413 C CG  . GLN A 1 205 ? 143.366 140.409 194.522 1.00 84.95  ? 205 GLN C CG  1 
ATOM 1414 C CD  . GLN A 1 205 ? 142.798 139.063 194.148 1.00 84.95  ? 205 GLN C CD  1 
ATOM 1415 O OE1 . GLN A 1 205 ? 143.499 138.055 194.168 1.00 84.95  ? 205 GLN C OE1 1 
ATOM 1416 N NE2 . GLN A 1 205 ? 141.508 139.033 193.836 1.00 84.95  ? 205 GLN C NE2 1 
ATOM 1417 N N   . LEU A 1 206 ? 143.506 144.072 191.530 1.00 76.00  ? 206 LEU C N   1 
ATOM 1418 C CA  . LEU A 1 206 ? 144.091 145.053 190.626 1.00 76.00  ? 206 LEU C CA  1 
ATOM 1419 C C   . LEU A 1 206 ? 143.997 146.471 191.168 1.00 76.00  ? 206 LEU C C   1 
ATOM 1420 O O   . LEU A 1 206 ? 144.727 147.348 190.695 1.00 76.00  ? 206 LEU C O   1 
ATOM 1421 C CB  . LEU A 1 206 ? 143.422 144.980 189.249 1.00 76.00  ? 206 LEU C CB  1 
ATOM 1422 C CG  . LEU A 1 206 ? 143.837 143.863 188.282 1.00 76.00  ? 206 LEU C CG  1 
ATOM 1423 C CD1 . LEU A 1 206 ? 143.741 142.486 188.903 1.00 76.00  ? 206 LEU C CD1 1 
ATOM 1424 C CD2 . LEU A 1 206 ? 143.029 143.912 187.000 1.00 76.00  ? 206 LEU C CD2 1 
ATOM 1425 N N   . THR A 1 207 ? 143.123 146.715 192.141 1.00 81.66  ? 207 THR C N   1 
ATOM 1426 C CA  . THR A 1 207 ? 143.047 147.996 192.826 1.00 81.66  ? 207 THR C CA  1 
ATOM 1427 C C   . THR A 1 207 ? 143.758 147.953 194.171 1.00 81.66  ? 207 THR C C   1 
ATOM 1428 O O   . THR A 1 207 ? 144.281 148.980 194.620 1.00 81.66  ? 207 THR C O   1 
ATOM 1429 C CB  . THR A 1 207 ? 141.574 148.406 192.999 1.00 81.66  ? 207 THR C CB  1 
ATOM 1430 O OG1 . THR A 1 207 ? 141.037 148.795 191.729 1.00 81.66  ? 207 THR C OG1 1 
ATOM 1431 C CG2 . THR A 1 207 ? 141.419 149.568 193.972 1.00 81.66  ? 207 THR C CG2 1 
ATOM 1432 N N   . GLU A 1 208 ? 143.834 146.776 194.797 1.00 86.90  ? 208 GLU C N   1 
ATOM 1433 C CA  . GLU A 1 208 ? 144.560 146.638 196.054 1.00 86.90  ? 208 GLU C CA  1 
ATOM 1434 C C   . GLU A 1 208 ? 146.026 147.013 195.882 1.00 86.90  ? 208 GLU C C   1 
ATOM 1435 O O   . GLU A 1 208 ? 146.600 147.718 196.720 1.00 86.90  ? 208 GLU C O   1 
ATOM 1436 C CB  . GLU A 1 208 ? 144.434 145.205 196.575 1.00 86.90  ? 208 GLU C CB  1 
ATOM 1437 C CG  . GLU A 1 208 ? 143.334 144.999 197.601 1.00 86.90  ? 208 GLU C CG  1 
ATOM 1438 C CD  . GLU A 1 208 ? 143.808 145.233 199.020 1.00 86.90  ? 208 GLU C CD  1 
ATOM 1439 O OE1 . GLU A 1 208 ? 145.007 145.530 199.206 1.00 86.90  ? 208 GLU C OE1 1 
ATOM 1440 O OE2 . GLU A 1 208 ? 142.984 145.114 199.952 1.00 86.90  ? 208 GLU C OE2 1 
ATOM 1441 N N   . VAL A 1 209 ? 146.650 146.551 194.799 1.00 64.00  ? 209 VAL C N   1 
ATOM 1442 C CA  . VAL A 1 209 ? 148.059 146.831 194.549 1.00 64.00  ? 209 VAL C CA  1 
ATOM 1443 C C   . VAL A 1 209 ? 148.204 148.016 193.598 1.00 64.00  ? 209 VAL C C   1 
ATOM 1444 O O   . VAL A 1 209 ? 149.094 148.853 193.776 1.00 64.00  ? 209 VAL C O   1 
ATOM 1445 C CB  . VAL A 1 209 ? 148.787 145.573 194.036 1.00 64.00  ? 209 VAL C CB  1 
ATOM 1446 C CG1 . VAL A 1 209 ? 148.435 144.385 194.910 1.00 64.00  ? 209 VAL C CG1 1 
ATOM 1447 C CG2 . VAL A 1 209 ? 148.418 145.267 192.604 1.00 64.00  ? 209 VAL C CG2 1 
ATOM 1448 N N   . GLY A 1 210 ? 147.333 148.113 192.595 1.00 63.22  ? 210 GLY C N   1 
ATOM 1449 C CA  . GLY A 1 210 ? 147.330 149.293 191.752 1.00 63.22  ? 210 GLY C CA  1 
ATOM 1450 C C   . GLY A 1 210 ? 147.518 149.074 190.263 1.00 63.22  ? 210 GLY C C   1 
ATOM 1451 O O   . GLY A 1 210 ? 147.856 150.017 189.542 1.00 63.22  ? 210 GLY C O   1 
ATOM 1452 N N   . LEU A 1 211 ? 147.312 147.850 189.783 1.00 59.91  ? 211 LEU C N   1 
ATOM 1453 C CA  . LEU A 1 211 ? 147.414 147.565 188.357 1.00 59.91  ? 211 LEU C CA  1 
ATOM 1454 C C   . LEU A 1 211 ? 146.285 148.178 187.536 1.00 59.91  ? 211 LEU C C   1 
ATOM 1455 O O   . LEU A 1 211 ? 146.435 148.321 186.319 1.00 59.91  ? 211 LEU C O   1 
ATOM 1456 C CB  . LEU A 1 211 ? 147.460 146.053 188.108 1.00 59.91  ? 211 LEU C CB  1 
ATOM 1457 C CG  . LEU A 1 211 ? 148.354 145.148 188.954 1.00 59.91  ? 211 LEU C CG  1 
ATOM 1458 C CD1 . LEU A 1 211 ? 148.666 143.892 188.170 1.00 59.91  ? 211 LEU C CD1 1 
ATOM 1459 C CD2 . LEU A 1 211 ? 149.655 145.850 189.305 1.00 59.91  ? 211 LEU C CD2 1 
ATOM 1460 N N   . LEU A 1 212 ? 145.170 148.546 188.161 1.00 67.78  ? 212 LEU C N   1 
ATOM 1461 C CA  . LEU A 1 212 ? 144.079 149.194 187.447 1.00 67.78  ? 212 LEU C CA  1 
ATOM 1462 C C   . LEU A 1 212 ? 143.668 150.454 188.189 1.00 67.78  ? 212 LEU C C   1 
ATOM 1463 O O   . LEU A 1 212 ? 143.988 150.641 189.365 1.00 67.78  ? 212 LEU C O   1 
ATOM 1464 C CB  . LEU A 1 212 ? 142.863 148.278 187.276 1.00 67.78  ? 212 LEU C CB  1 
ATOM 1465 C CG  . LEU A 1 212 ? 142.673 147.669 185.888 1.00 67.78  ? 212 LEU C CG  1 
ATOM 1466 C CD1 . LEU A 1 212 ? 141.437 146.789 185.858 1.00 67.78  ? 212 LEU C CD1 1 
ATOM 1467 C CD2 . LEU A 1 212 ? 142.580 148.764 184.840 1.00 67.78  ? 212 LEU C CD2 1 
ATOM 1468 N N   . ASP A 1 213 ? 142.958 151.324 187.471 1.00 72.66  ? 213 ASP C N   1 
ATOM 1469 C CA  . ASP A 1 213 ? 142.457 152.591 187.997 1.00 72.66  ? 213 ASP C CA  1 
ATOM 1470 C C   . ASP A 1 213 ? 143.578 153.485 188.513 1.00 72.66  ? 213 ASP C C   1 
ATOM 1471 O O   . ASP A 1 213 ? 143.334 154.402 189.303 1.00 72.66  ? 213 ASP C O   1 
ATOM 1472 C CB  . ASP A 1 213 ? 141.410 152.361 189.094 1.00 72.66  ? 213 ASP C CB  1 
ATOM 1473 C CG  . ASP A 1 213 ? 140.394 151.300 188.715 1.00 72.66  ? 213 ASP C CG  1 
ATOM 1474 O OD1 . ASP A 1 213 ? 139.568 151.560 187.815 1.00 72.66  ? 213 ASP C OD1 1 
ATOM 1475 O OD2 . ASP A 1 213 ? 140.421 150.206 189.317 1.00 72.66  ? 213 ASP C OD2 1 
ATOM 1476 N N   . ASN A 1 214 ? 144.810 153.231 188.076 1.00 60.76  ? 214 ASN C N   1 
ATOM 1477 C CA  . ASN A 1 214 ? 145.946 154.050 188.458 1.00 60.76  ? 214 ASN C CA  1 
ATOM 1478 C C   . ASN A 1 214 ? 146.334 154.925 187.280 1.00 60.76  ? 214 ASN C C   1 
ATOM 1479 O O   . ASN A 1 214 ? 146.855 154.405 186.282 1.00 60.76  ? 214 ASN C O   1 
ATOM 1480 C CB  . ASN A 1 214 ? 147.120 153.176 188.881 1.00 60.76  ? 214 ASN C CB  1 
ATOM 1481 C CG  . ASN A 1 214 ? 148.255 153.974 189.487 1.00 60.76  ? 214 ASN C CG  1 
ATOM 1482 O OD1 . ASN A 1 214 ? 148.156 155.188 189.659 1.00 60.76  ? 214 ASN C OD1 1 
ATOM 1483 N ND2 . ASN A 1 214 ? 149.344 153.291 189.819 1.00 60.76  ? 214 ASN C ND2 1 
ATOM 1484 N N   . PRO A 1 215 ? 146.103 156.239 187.339 1.00 60.96  ? 215 PRO C N   1 
ATOM 1485 C CA  . PRO A 1 215 ? 146.407 157.098 186.186 1.00 60.96  ? 215 PRO C CA  1 
ATOM 1486 C C   . PRO A 1 215 ? 147.890 157.273 185.913 1.00 60.96  ? 215 PRO C C   1 
ATOM 1487 O O   . PRO A 1 215 ? 148.241 157.944 184.936 1.00 60.96  ? 215 PRO C O   1 
ATOM 1488 C CB  . PRO A 1 215 ? 145.761 158.438 186.572 1.00 60.96  ? 215 PRO C CB  1 
ATOM 1489 C CG  . PRO A 1 215 ? 145.695 158.408 188.061 1.00 60.96  ? 215 PRO C CG  1 
ATOM 1490 C CD  . PRO A 1 215 ? 145.441 156.979 188.426 1.00 60.96  ? 215 PRO C CD  1 
ATOM 1491 N N   . GLU A 1 216 ? 148.778 156.697 186.730 1.00 58.98  ? 216 GLU C N   1 
ATOM 1492 C CA  . GLU A 1 216 ? 150.204 156.925 186.536 1.00 58.98  ? 216 GLU C CA  1 
ATOM 1493 C C   . GLU A 1 216 ? 151.002 155.626 186.457 1.00 58.98  ? 216 GLU C C   1 
ATOM 1494 O O   . GLU A 1 216 ? 152.234 155.661 186.563 1.00 58.98  ? 216 GLU C O   1 
ATOM 1495 C CB  . GLU A 1 216 ? 150.765 157.808 187.655 1.00 58.98  ? 216 GLU C CB  1 
ATOM 1496 C CG  . GLU A 1 216 ? 150.517 159.297 187.456 1.00 58.98  ? 216 GLU C CG  1 
ATOM 1497 C CD  . GLU A 1 216 ? 150.811 159.763 186.042 1.00 58.98  ? 216 GLU C CD  1 
ATOM 1498 O OE1 . GLU A 1 216 ? 151.931 159.515 185.548 1.00 58.98  ? 216 GLU C OE1 1 
ATOM 1499 O OE2 . GLU A 1 216 ? 149.920 160.382 185.423 1.00 58.98  ? 216 GLU C OE2 1 
ATOM 1500 N N   . LEU A 1 217 ? 150.340 154.483 186.277 1.00 52.78  ? 217 LEU C N   1 
ATOM 1501 C CA  . LEU A 1 217 ? 151.044 153.224 186.066 1.00 52.78  ? 217 LEU C CA  1 
ATOM 1502 C C   . LEU A 1 217 ? 151.741 153.239 184.715 1.00 52.78  ? 217 LEU C C   1 
ATOM 1503 O O   . LEU A 1 217 ? 151.083 153.378 183.679 1.00 52.78  ? 217 LEU C O   1 
ATOM 1504 C CB  . LEU A 1 217 ? 150.079 152.041 186.144 1.00 52.78  ? 217 LEU C CB  1 
ATOM 1505 C CG  . LEU A 1 217 ? 150.718 150.676 186.390 1.00 52.78  ? 217 LEU C CG  1 
ATOM 1506 C CD1 . LEU A 1 217 ? 151.235 150.584 187.810 1.00 52.78  ? 217 LEU C CD1 1 
ATOM 1507 C CD2 . LEU A 1 217 ? 149.731 149.563 186.103 1.00 52.78  ? 217 LEU C CD2 1 
ATOM 1508 N N   . ARG A 1 218 ? 153.065 153.102 184.703 1.00 46.82  ? 218 ARG C N   1 
ATOM 1509 C CA  . ARG A 1 218 ? 153.790 153.201 183.444 1.00 46.82  ? 218 ARG C CA  1 
ATOM 1510 C C   . ARG A 1 218 ? 154.661 151.989 183.146 1.00 46.82  ? 218 ARG C C   1 
ATOM 1511 O O   . ARG A 1 218 ? 154.869 151.670 181.971 1.00 46.82  ? 218 ARG C O   1 
ATOM 1512 C CB  . ARG A 1 218 ? 154.639 154.473 183.431 1.00 46.82  ? 218 ARG C CB  1 
ATOM 1513 C CG  . ARG A 1 218 ? 153.799 155.728 183.560 1.00 46.82  ? 218 ARG C CG  1 
ATOM 1514 C CD  . ARG A 1 218 ? 154.302 156.851 182.680 1.00 46.82  ? 218 ARG C CD  1 
ATOM 1515 N NE  . ARG A 1 218 ? 154.025 158.155 183.268 1.00 46.82  ? 218 ARG C NE  1 
ATOM 1516 C CZ  . ARG A 1 218 ? 154.568 159.292 182.858 1.00 46.82  ? 218 ARG C CZ  1 
ATOM 1517 N NH1 . ARG A 1 218 ? 155.419 159.326 181.847 1.00 46.82  ? 218 ARG C NH1 1 
ATOM 1518 N NH2 . ARG A 1 218 ? 154.248 160.424 183.478 1.00 46.82  ? 218 ARG C NH2 1 
ATOM 1519 N N   . VAL A 1 219 ? 155.177 151.303 184.163 1.00 38.68  ? 219 VAL C N   1 
ATOM 1520 C CA  . VAL A 1 219 ? 156.002 150.116 183.958 1.00 38.68  ? 219 VAL C CA  1 
ATOM 1521 C C   . VAL A 1 219 ? 155.539 149.018 184.903 1.00 38.68  ? 219 VAL C C   1 
ATOM 1522 O O   . VAL A 1 219 ? 155.293 149.274 186.086 1.00 38.68  ? 219 VAL C O   1 
ATOM 1523 C CB  . VAL A 1 219 ? 157.501 150.399 184.177 1.00 38.68  ? 219 VAL C CB  1 
ATOM 1524 C CG1 . VAL A 1 219 ? 158.318 149.174 183.817 1.00 38.68  ? 219 VAL C CG1 1 
ATOM 1525 C CG2 . VAL A 1 219 ? 157.951 151.596 183.361 1.00 38.68  ? 219 VAL C CG2 1 
ATOM 1526 N N   . VAL A 1 220 ? 155.428 147.798 184.386 1.00 28.77  ? 220 VAL C N   1 
ATOM 1527 C CA  . VAL A 1 220 ? 155.166 146.621 185.199 1.00 28.77  ? 220 VAL C CA  1 
ATOM 1528 C C   . VAL A 1 220 ? 156.199 145.559 184.825 1.00 28.77  ? 220 VAL C C   1 
ATOM 1529 O O   . VAL A 1 220 ? 156.715 145.528 183.708 1.00 28.77  ? 220 VAL C O   1 
ATOM 1530 C CB  . VAL A 1 220 ? 153.725 146.097 185.025 1.00 28.77  ? 220 VAL C CB  1 
ATOM 1531 C CG1 . VAL A 1 220 ? 153.495 145.615 183.608 1.00 28.77  ? 220 VAL C CG1 1 
ATOM 1532 C CG2 . VAL A 1 220 ? 153.406 145.009 186.038 1.00 28.77  ? 220 VAL C CG2 1 
ATOM 1533 N N   . LEU A 1 221 ? 156.507 144.692 185.785 1.00 36.02  ? 221 LEU C N   1 
ATOM 1534 C CA  . LEU A 1 221 ? 157.590 143.726 185.634 1.00 36.02  ? 221 LEU C CA  1 
ATOM 1535 C C   . LEU A 1 221 ? 157.082 142.324 185.959 1.00 36.02  ? 221 LEU C C   1 
ATOM 1536 O O   . LEU A 1 221 ? 157.664 141.600 186.766 1.00 36.02  ? 221 LEU C O   1 
ATOM 1537 C CB  . LEU A 1 221 ? 158.782 144.103 186.514 1.00 36.02  ? 221 LEU C CB  1 
ATOM 1538 C CG  . LEU A 1 221 ? 159.703 145.199 185.980 1.00 36.02  ? 221 LEU C CG  1 
ATOM 1539 C CD1 . LEU A 1 221 ? 160.717 145.593 187.033 1.00 36.02  ? 221 LEU C CD1 1 
ATOM 1540 C CD2 . LEU A 1 221 ? 160.397 144.747 184.714 1.00 36.02  ? 221 LEU C CD2 1 
ATOM 1541 N N   . VAL A 1 222 ? 155.966 141.940 185.341 1.00 40.70  ? 222 VAL C N   1 
ATOM 1542 C CA  . VAL A 1 222 ? 155.298 140.668 185.604 1.00 40.70  ? 222 VAL C CA  1 
ATOM 1543 C C   . VAL A 1 222 ? 156.253 139.488 185.485 1.00 40.70  ? 222 VAL C C   1 
ATOM 1544 O O   . VAL A 1 222 ? 156.956 139.339 184.479 1.00 40.70  ? 222 VAL C O   1 
ATOM 1545 C CB  . VAL A 1 222 ? 154.103 140.487 184.653 1.00 40.70  ? 222 VAL C CB  1 
ATOM 1546 C CG1 . VAL A 1 222 ? 153.513 139.099 184.797 1.00 40.70  ? 222 VAL C CG1 1 
ATOM 1547 C CG2 . VAL A 1 222 ? 153.053 141.543 184.925 1.00 40.70  ? 222 VAL C CG2 1 
ATOM 1548 N N   . PHE A 1 223 ? 156.279 138.642 186.513 1.00 48.27  ? 223 PHE C N   1 
ATOM 1549 C CA  . PHE A 1 223 ? 157.024 137.394 186.517 1.00 48.27  ? 223 PHE C CA  1 
ATOM 1550 C C   . PHE A 1 223 ? 156.059 136.240 186.755 1.00 48.27  ? 223 PHE C C   1 
ATOM 1551 O O   . PHE A 1 223 ? 154.968 136.422 187.302 1.00 48.27  ? 223 PHE C O   1 
ATOM 1552 C CB  . PHE A 1 223 ? 158.108 137.382 187.602 1.00 48.27  ? 223 PHE C CB  1 
ATOM 1553 C CG  . PHE A 1 223 ? 159.198 138.389 187.389 1.00 48.27  ? 223 PHE C CG  1 
ATOM 1554 C CD1 . PHE A 1 223 ? 160.114 138.236 186.368 1.00 48.27  ? 223 PHE C CD1 1 
ATOM 1555 C CD2 . PHE A 1 223 ? 159.306 139.490 188.218 1.00 48.27  ? 223 PHE C CD2 1 
ATOM 1556 C CE1 . PHE A 1 223 ? 161.117 139.165 186.176 1.00 48.27  ? 223 PHE C CE1 1 
ATOM 1557 C CE2 . PHE A 1 223 ? 160.306 140.421 188.031 1.00 48.27  ? 223 PHE C CE2 1 
ATOM 1558 C CZ  . PHE A 1 223 ? 161.212 140.258 187.009 1.00 48.27  ? 223 PHE C CZ  1 
ATOM 1559 N N   . GLY A 1 224 ? 156.470 135.045 186.349 1.00 60.47  ? 224 GLY C N   1 
ATOM 1560 C CA  . GLY A 1 224 ? 155.637 133.871 186.526 1.00 60.47  ? 224 GLY C CA  1 
ATOM 1561 C C   . GLY A 1 224 ? 156.477 132.664 186.860 1.00 60.47  ? 224 GLY C C   1 
ATOM 1562 O O   . GLY A 1 224 ? 157.633 132.558 186.440 1.00 60.47  ? 224 GLY C O   1 
ATOM 1563 N N   . TYR A 1 225 ? 155.892 131.743 187.625 1.00 74.09  ? 225 TYR C N   1 
ATOM 1564 C CA  . TYR A 1 225 ? 156.627 130.564 188.066 1.00 74.09  ? 225 TYR C CA  1 
ATOM 1565 C C   . TYR A 1 225 ? 155.758 129.313 188.076 1.00 74.09  ? 225 TYR C C   1 
ATOM 1566 O O   . TYR A 1 225 ? 154.535 129.400 188.225 1.00 74.09  ? 225 TYR C O   1 
ATOM 1567 C CB  . TYR A 1 225 ? 157.225 130.800 189.454 1.00 74.09  ? 225 TYR C CB  1 
ATOM 1568 C CG  . TYR A 1 225 ? 156.224 131.203 190.513 1.00 74.09  ? 225 TYR C CG  1 
ATOM 1569 C CD1 . TYR A 1 225 ? 155.764 132.510 190.601 1.00 74.09  ? 225 TYR C CD1 1 
ATOM 1570 C CD2 . TYR A 1 225 ? 155.744 130.280 191.430 1.00 74.09  ? 225 TYR C CD2 1 
ATOM 1571 C CE1 . TYR A 1 225 ? 154.853 132.884 191.569 1.00 74.09  ? 225 TYR C CE1 1 
ATOM 1572 C CE2 . TYR A 1 225 ? 154.834 130.646 192.402 1.00 74.09  ? 225 TYR C CE2 1 
ATOM 1573 C CZ  . TYR A 1 225 ? 154.392 131.949 192.467 1.00 74.09  ? 225 TYR C CZ  1 
ATOM 1574 O OH  . TYR A 1 225 ? 153.485 132.317 193.433 1.00 74.09  ? 225 TYR C OH  1 
ATOM 1575 N N   . ASN A 1 226 ? 156.394 128.147 187.928 1.00 84.05  ? 226 ASN C N   1 
ATOM 1576 C CA  . ASN A 1 226 ? 155.721 126.852 187.934 1.00 84.05  ? 226 ASN C CA  1 
ATOM 1577 C C   . ASN A 1 226 ? 154.574 126.806 186.932 1.00 84.05  ? 226 ASN C C   1 
ATOM 1578 O O   . ASN A 1 226 ? 153.466 126.373 187.264 1.00 84.05  ? 226 ASN C O   1 
ATOM 1579 C CB  . ASN A 1 226 ? 155.214 126.518 189.338 1.00 84.05  ? 226 ASN C CB  1 
ATOM 1580 C CG  . ASN A 1 226 ? 156.336 126.196 190.303 1.00 84.05  ? 226 ASN C CG  1 
ATOM 1581 O OD1 . ASN A 1 226 ? 157.419 125.777 189.895 1.00 84.05  ? 226 ASN C OD1 1 
ATOM 1582 N ND2 . ASN A 1 226 ? 156.084 126.392 191.592 1.00 84.05  ? 226 ASN C ND2 1 
ATOM 1583 N N   . CYS A 1 227 ? 154.833 127.247 185.700 1.00 102.58 ? 227 CYS C N   1 
ATOM 1584 C CA  . CYS A 1 227 ? 153.780 127.298 184.691 1.00 102.58 ? 227 CYS C CA  1 
ATOM 1585 C C   . CYS A 1 227 ? 153.701 125.993 183.906 1.00 102.58 ? 227 CYS C C   1 
ATOM 1586 O O   . CYS A 1 227 ? 152.962 125.896 182.920 1.00 102.58 ? 227 CYS C O   1 
ATOM 1587 C CB  . CYS A 1 227 ? 154.017 128.480 183.751 1.00 102.58 ? 227 CYS C CB  1 
ATOM 1588 S SG  . CYS A 1 227 ? 154.644 129.963 184.571 1.00 102.58 ? 227 CYS C SG  1 
ATOM 1589 N N   . CYS A 1 228 ? 154.466 124.983 184.323 1.00 120.20 ? 228 CYS C N   1 
ATOM 1590 C CA  . CYS A 1 228 ? 154.543 123.711 183.611 1.00 120.20 ? 228 CYS C CA  1 
ATOM 1591 C C   . CYS A 1 228 ? 153.183 123.034 183.476 1.00 120.20 ? 228 CYS C C   1 
ATOM 1592 O O   . CYS A 1 228 ? 152.823 122.570 182.389 1.00 120.20 ? 228 CYS C O   1 
ATOM 1593 C CB  . CYS A 1 228 ? 155.524 122.772 184.317 1.00 120.20 ? 228 CYS C CB  1 
ATOM 1594 S SG  . CYS A 1 228 ? 157.245 122.969 183.805 1.00 120.20 ? 228 CYS C SG  1 
ATOM 1595 N N   . LYS A 1 229 ? 152.426 122.966 184.570 1.00 120.73 ? 229 LYS C N   1 
ATOM 1596 C CA  . LYS A 1 229 ? 151.125 122.309 184.543 1.00 120.73 ? 229 LYS C CA  1 
ATOM 1597 C C   . LYS A 1 229 ? 150.157 123.069 183.644 1.00 120.73 ? 229 LYS C C   1 
ATOM 1598 O O   . LYS A 1 229 ? 150.198 124.300 183.550 1.00 120.73 ? 229 LYS C O   1 
ATOM 1599 C CB  . LYS A 1 229 ? 150.557 122.200 185.961 1.00 120.73 ? 229 LYS C CB  1 
ATOM 1600 C CG  . LYS A 1 229 ? 149.190 121.533 186.046 1.00 120.73 ? 229 LYS C CG  1 
ATOM 1601 C CD  . LYS A 1 229 ? 149.272 120.047 185.738 1.00 120.73 ? 229 LYS C CD  1 
ATOM 1602 C CE  . LYS A 1 229 ? 150.153 119.325 186.741 1.00 120.73 ? 229 LYS C CE  1 
ATOM 1603 N NZ  . LYS A 1 229 ? 149.740 119.617 188.141 1.00 120.73 ? 229 LYS C NZ  1 
ATOM 1604 N N   . VAL A 1 230 ? 149.285 122.320 182.968 1.00 123.49 ? 230 VAL C N   1 
ATOM 1605 C CA  . VAL A 1 230 ? 148.241 122.906 182.135 1.00 123.49 ? 230 VAL C CA  1 
ATOM 1606 C C   . VAL A 1 230 ? 147.320 123.728 183.026 1.00 123.49 ? 230 VAL C C   1 
ATOM 1607 O O   . VAL A 1 230 ? 147.223 123.483 184.234 1.00 123.49 ? 230 VAL C O   1 
ATOM 1608 C CB  . VAL A 1 230 ? 147.462 121.826 181.358 1.00 123.49 ? 230 VAL C CB  1 
ATOM 1609 C CG1 . VAL A 1 230 ? 146.331 121.257 182.204 1.00 123.49 ? 230 VAL C CG1 1 
ATOM 1610 C CG2 . VAL A 1 230 ? 146.925 122.394 180.053 1.00 123.49 ? 230 VAL C CG2 1 
ATOM 1611 N N   . GLY A 1 231 ? 146.650 124.712 182.445 1.00 115.19 ? 231 GLY C N   1 
ATOM 1612 C CA  . GLY A 1 231 ? 145.909 125.671 183.260 1.00 115.19 ? 231 GLY C CA  1 
ATOM 1613 C C   . GLY A 1 231 ? 146.806 126.728 183.860 1.00 115.19 ? 231 GLY C C   1 
ATOM 1614 O O   . GLY A 1 231 ? 146.541 127.924 183.709 1.00 115.19 ? 231 GLY C O   1 
ATOM 1615 N N   . ALA A 1 232 ? 147.874 126.312 184.546 1.00 114.07 ? 232 ALA C N   1 
ATOM 1616 C CA  . ALA A 1 232 ? 148.884 127.255 185.011 1.00 114.07 ? 232 ALA C CA  1 
ATOM 1617 C C   . ALA A 1 232 ? 149.595 127.936 183.851 1.00 114.07 ? 232 ALA C C   1 
ATOM 1618 O O   . ALA A 1 232 ? 149.876 129.138 183.920 1.00 114.07 ? 232 ALA C O   1 
ATOM 1619 C CB  . ALA A 1 232 ? 149.901 126.545 185.906 1.00 114.07 ? 232 ALA C CB  1 
ATOM 1620 N N   . SER A 1 233 ? 149.899 127.188 182.788 1.00 112.06 ? 233 SER C N   1 
ATOM 1621 C CA  . SER A 1 233 ? 150.437 127.804 181.581 1.00 112.06 ? 233 SER C CA  1 
ATOM 1622 C C   . SER A 1 233 ? 149.441 128.794 180.995 1.00 112.06 ? 233 SER C C   1 
ATOM 1623 O O   . SER A 1 233 ? 149.816 129.881 180.542 1.00 112.06 ? 233 SER C O   1 
ATOM 1624 C CB  . SER A 1 233 ? 150.797 126.726 180.557 1.00 112.06 ? 233 SER C CB  1 
ATOM 1625 O OG  . SER A 1 233 ? 149.747 125.785 180.420 1.00 112.06 ? 233 SER C OG  1 
ATOM 1626 N N   . ASN A 1 234 ? 148.162 128.434 181.000 1.00 99.53  ? 234 ASN C N   1 
ATOM 1627 C CA  . ASN A 1 234 ? 147.111 129.354 180.592 1.00 99.53  ? 234 ASN C CA  1 
ATOM 1628 C C   . ASN A 1 234 ? 146.737 130.335 181.681 1.00 99.53  ? 234 ASN C C   1 
ATOM 1629 O O   . ASN A 1 234 ? 146.033 131.303 181.374 1.00 99.53  ? 234 ASN C O   1 
ATOM 1630 C CB  . ASN A 1 234 ? 145.874 128.574 180.146 1.00 99.53  ? 234 ASN C CB  1 
ATOM 1631 C CG  . ASN A 1 234 ? 146.117 127.765 178.891 1.00 99.53  ? 234 ASN C CG  1 
ATOM 1632 O OD1 . ASN A 1 234 ? 147.059 128.028 178.144 1.00 99.53  ? 234 ASN C OD1 1 
ATOM 1633 N ND2 . ASN A 1 234 ? 145.265 126.777 178.650 1.00 99.53  ? 234 ASN C ND2 1 
ATOM 1634 N N   . TYR A 1 235 ? 147.154 130.135 182.933 1.00 91.15  ? 235 TYR C N   1 
ATOM 1635 C CA  . TYR A 1 235 ? 146.878 131.130 183.963 1.00 91.15  ? 235 TYR C CA  1 
ATOM 1636 C C   . TYR A 1 235 ? 147.580 132.439 183.631 1.00 91.15  ? 235 TYR C C   1 
ATOM 1637 O O   . TYR A 1 235 ? 146.977 133.515 183.717 1.00 91.15  ? 235 TYR C O   1 
ATOM 1638 C CB  . TYR A 1 235 ? 147.304 130.597 185.339 1.00 91.15  ? 235 TYR C CB  1 
ATOM 1639 C CG  . TYR A 1 235 ? 146.916 131.452 186.539 1.00 91.15  ? 235 TYR C CG  1 
ATOM 1640 C CD1 . TYR A 1 235 ? 147.310 132.781 186.650 1.00 91.15  ? 235 TYR C CD1 1 
ATOM 1641 C CD2 . TYR A 1 235 ? 146.142 130.919 187.560 1.00 91.15  ? 235 TYR C CD2 1 
ATOM 1642 C CE1 . TYR A 1 235 ? 146.948 133.546 187.739 1.00 91.15  ? 235 TYR C CE1 1 
ATOM 1643 C CE2 . TYR A 1 235 ? 145.778 131.678 188.654 1.00 91.15  ? 235 TYR C CE2 1 
ATOM 1644 C CZ  . TYR A 1 235 ? 146.183 132.989 188.738 1.00 91.15  ? 235 TYR C CZ  1 
ATOM 1645 O OH  . TYR A 1 235 ? 145.821 133.748 189.827 1.00 91.15  ? 235 TYR C OH  1 
ATOM 1646 N N   . LEU A 1 236 ? 148.852 132.362 183.231 1.00 77.88  ? 236 LEU C N   1 
ATOM 1647 C CA  . LEU A 1 236 ? 149.565 133.561 182.807 1.00 77.88  ? 236 LEU C CA  1 
ATOM 1648 C C   . LEU A 1 236 ? 148.898 134.194 181.595 1.00 77.88  ? 236 LEU C C   1 
ATOM 1649 O O   . LEU A 1 236 ? 148.945 135.418 181.426 1.00 77.88  ? 236 LEU C O   1 
ATOM 1650 C CB  . LEU A 1 236 ? 151.025 133.226 182.501 1.00 77.88  ? 236 LEU C CB  1 
ATOM 1651 C CG  . LEU A 1 236 ? 151.949 134.426 182.298 1.00 77.88  ? 236 LEU C CG  1 
ATOM 1652 C CD1 . LEU A 1 236 ? 152.037 135.240 183.573 1.00 77.88  ? 236 LEU C CD1 1 
ATOM 1653 C CD2 . LEU A 1 236 ? 153.328 133.982 181.846 1.00 77.88  ? 236 LEU C CD2 1 
ATOM 1654 N N   . GLN A 1 237 ? 148.271 133.379 180.744 1.00 83.72  ? 237 GLN C N   1 
ATOM 1655 C CA  . GLN A 1 237 ? 147.495 133.911 179.629 1.00 83.72  ? 237 GLN C CA  1 
ATOM 1656 C C   . GLN A 1 237 ? 146.335 134.765 180.129 1.00 83.72  ? 237 GLN C C   1 
ATOM 1657 O O   . GLN A 1 237 ? 146.075 135.851 179.599 1.00 83.72  ? 237 GLN C O   1 
ATOM 1658 C CB  . GLN A 1 237 ? 146.977 132.760 178.762 1.00 83.72  ? 237 GLN C CB  1 
ATOM 1659 C CG  . GLN A 1 237 ? 147.975 132.135 177.780 1.00 83.72  ? 237 GLN C CG  1 
ATOM 1660 C CD  . GLN A 1 237 ? 148.429 133.065 176.664 1.00 83.72  ? 237 GLN C CD  1 
ATOM 1661 O OE1 . GLN A 1 237 ? 148.644 134.257 176.867 1.00 83.72  ? 237 GLN C OE1 1 
ATOM 1662 N NE2 . GLN A 1 237 ? 148.575 132.510 175.467 1.00 83.72  ? 237 GLN C NE2 1 
ATOM 1663 N N   . GLN A 1 238 ? 145.625 134.287 181.155 1.00 81.39  ? 238 GLN C N   1 
ATOM 1664 C CA  . GLN A 1 238 ? 144.423 134.976 181.612 1.00 81.39  ? 238 GLN C CA  1 
ATOM 1665 C C   . GLN A 1 238 ? 144.742 136.155 182.522 1.00 81.39  ? 238 GLN C C   1 
ATOM 1666 O O   . GLN A 1 238 ? 144.148 137.228 182.367 1.00 81.39  ? 238 GLN C O   1 
ATOM 1667 C CB  . GLN A 1 238 ? 143.495 133.997 182.331 1.00 81.39  ? 238 GLN C CB  1 
ATOM 1668 C CG  . GLN A 1 238 ? 143.072 132.810 181.486 1.00 81.39  ? 238 GLN C CG  1 
ATOM 1669 C CD  . GLN A 1 238 ? 143.167 131.499 182.236 1.00 81.39  ? 238 GLN C CD  1 
ATOM 1670 O OE1 . GLN A 1 238 ? 143.466 131.475 183.429 1.00 81.39  ? 238 GLN C OE1 1 
ATOM 1671 N NE2 . GLN A 1 238 ? 142.917 130.399 181.538 1.00 81.39  ? 238 GLN C NE2 1 
ATOM 1672 N N   . VAL A 1 239 ? 145.665 135.981 183.471 1.00 74.57  ? 239 VAL C N   1 
ATOM 1673 C CA  . VAL A 1 239 ? 145.896 137.013 184.475 1.00 74.57  ? 239 VAL C CA  1 
ATOM 1674 C C   . VAL A 1 239 ? 146.420 138.299 183.854 1.00 74.57  ? 239 VAL C C   1 
ATOM 1675 O O   . VAL A 1 239 ? 146.067 139.391 184.314 1.00 74.57  ? 239 VAL C O   1 
ATOM 1676 C CB  . VAL A 1 239 ? 146.854 136.501 185.568 1.00 74.57  ? 239 VAL C CB  1 
ATOM 1677 C CG1 . VAL A 1 239 ? 148.207 136.151 184.979 1.00 74.57  ? 239 VAL C CG1 1 
ATOM 1678 C CG2 . VAL A 1 239 ? 147.000 137.533 186.677 1.00 74.57  ? 239 VAL C CG2 1 
ATOM 1679 N N   . VAL A 1 240 ? 147.238 138.203 182.808 1.00 74.70  ? 240 VAL C N   1 
ATOM 1680 C CA  . VAL A 1 240 ? 147.804 139.399 182.199 1.00 74.70  ? 240 VAL C CA  1 
ATOM 1681 C C   . VAL A 1 240 ? 146.728 140.255 181.536 1.00 74.70  ? 240 VAL C C   1 
ATOM 1682 O O   . VAL A 1 240 ? 146.796 141.489 181.588 1.00 74.70  ? 240 VAL C O   1 
ATOM 1683 C CB  . VAL A 1 240 ? 148.903 139.008 181.198 1.00 74.70  ? 240 VAL C CB  1 
ATOM 1684 C CG1 . VAL A 1 240 ? 148.315 138.202 180.061 1.00 74.70  ? 240 VAL C CG1 1 
ATOM 1685 C CG2 . VAL A 1 240 ? 149.577 140.238 180.660 1.00 74.70  ? 240 VAL C CG2 1 
ATOM 1686 N N   . SER A 1 241 ? 145.722 139.630 180.919 1.00 73.93  ? 241 SER C N   1 
ATOM 1687 C CA  . SER A 1 241 ? 144.756 140.376 180.120 1.00 73.93  ? 241 SER C CA  1 
ATOM 1688 C C   . SER A 1 241 ? 143.924 141.311 180.988 1.00 73.93  ? 241 SER C C   1 
ATOM 1689 O O   . SER A 1 241 ? 143.353 142.291 180.496 1.00 73.93  ? 241 SER C O   1 
ATOM 1690 C CB  . SER A 1 241 ? 143.856 139.407 179.355 1.00 73.93  ? 241 SER C CB  1 
ATOM 1691 O OG  . SER A 1 241 ? 142.776 138.976 180.162 1.00 73.93  ? 241 SER C OG  1 
ATOM 1692 N N   . THR A 1 242 ? 143.840 141.018 182.286 1.00 72.67  ? 242 THR C N   1 
ATOM 1693 C CA  . THR A 1 242 ? 143.034 141.839 183.182 1.00 72.67  ? 242 THR C CA  1 
ATOM 1694 C C   . THR A 1 242 ? 143.577 143.261 183.274 1.00 72.67  ? 242 THR C C   1 
ATOM 1695 O O   . THR A 1 242 ? 142.811 144.231 183.266 1.00 72.67  ? 242 THR C O   1 
ATOM 1696 C CB  . THR A 1 242 ? 142.972 141.193 184.565 1.00 72.67  ? 242 THR C CB  1 
ATOM 1697 O OG1 . THR A 1 242 ? 144.233 140.584 184.866 1.00 72.67  ? 242 THR C OG1 1 
ATOM 1698 C CG2 . THR A 1 242 ? 141.884 140.132 184.601 1.00 72.67  ? 242 THR C CG2 1 
ATOM 1699 N N   . PHE A 1 243 ? 144.900 143.407 183.364 1.00 69.07  ? 243 PHE C N   1 
ATOM 1700 C CA  . PHE A 1 243 ? 145.506 144.727 183.493 1.00 69.07  ? 243 PHE C CA  1 
ATOM 1701 C C   . PHE A 1 243 ? 146.292 145.153 182.259 1.00 69.07  ? 243 PHE C C   1 
ATOM 1702 O O   . PHE A 1 243 ? 147.082 146.100 182.346 1.00 69.07  ? 243 PHE C O   1 
ATOM 1703 C CB  . PHE A 1 243 ? 146.415 144.793 184.726 1.00 69.07  ? 243 PHE C CB  1 
ATOM 1704 C CG  . PHE A 1 243 ? 147.487 143.738 184.766 1.00 69.07  ? 243 PHE C CG  1 
ATOM 1705 C CD1 . PHE A 1 243 ? 147.186 142.422 185.068 1.00 69.07  ? 243 PHE C CD1 1 
ATOM 1706 C CD2 . PHE A 1 243 ? 148.808 144.081 184.548 1.00 69.07  ? 243 PHE C CD2 1 
ATOM 1707 C CE1 . PHE A 1 243 ? 148.178 141.465 185.116 1.00 69.07  ? 243 PHE C CE1 1 
ATOM 1708 C CE2 . PHE A 1 243 ? 149.802 143.128 184.594 1.00 69.07  ? 243 PHE C CE2 1 
ATOM 1709 C CZ  . PHE A 1 243 ? 149.486 141.819 184.879 1.00 69.07  ? 243 PHE C CZ  1 
ATOM 1710 N N   . SER A 1 244 ? 146.104 144.489 181.120 1.00 75.97  ? 244 SER C N   1 
ATOM 1711 C CA  . SER A 1 244 ? 146.780 144.890 179.892 1.00 75.97  ? 244 SER C CA  1 
ATOM 1712 C C   . SER A 1 244 ? 146.004 145.991 179.183 1.00 75.97  ? 244 SER C C   1 
ATOM 1713 O O   . SER A 1 244 ? 145.122 146.618 179.778 1.00 75.97  ? 244 SER C O   1 
ATOM 1714 C CB  . SER A 1 244 ? 146.966 143.695 178.957 1.00 75.97  ? 244 SER C CB  1 
ATOM 1715 O OG  . SER A 1 244 ? 147.250 142.516 179.683 1.00 75.97  ? 244 SER C OG  1 
ATOM 1716 N N   . ASP A 1 245 ? 146.359 146.252 177.923 1.00 86.23  ? 245 ASP C N   1 
ATOM 1717 C CA  . ASP A 1 245 ? 145.636 147.172 177.050 1.00 86.23  ? 245 ASP C CA  1 
ATOM 1718 C C   . ASP A 1 245 ? 145.756 148.619 177.511 1.00 86.23  ? 245 ASP C C   1 
ATOM 1719 O O   . ASP A 1 245 ? 145.112 149.508 176.945 1.00 86.23  ? 245 ASP C O   1 
ATOM 1720 C CB  . ASP A 1 245 ? 144.160 146.772 176.945 1.00 86.23  ? 245 ASP C CB  1 
ATOM 1721 C CG  . ASP A 1 245 ? 143.975 145.290 176.683 1.00 86.23  ? 245 ASP C CG  1 
ATOM 1722 O OD1 . ASP A 1 245 ? 144.438 144.809 175.628 1.00 86.23  ? 245 ASP C OD1 1 
ATOM 1723 O OD2 . ASP A 1 245 ? 143.367 144.607 177.534 1.00 86.23  ? 245 ASP C OD2 1 
ATOM 1724 N N   . MET A 1 246 ? 146.569 148.870 178.532 1.00 75.46  ? 246 MET C N   1 
ATOM 1725 C CA  . MET A 1 246 ? 146.790 150.226 179.012 1.00 75.46  ? 246 MET C CA  1 
ATOM 1726 C C   . MET A 1 246 ? 148.047 150.795 178.353 1.00 75.46  ? 246 MET C C   1 
ATOM 1727 O O   . MET A 1 246 ? 148.652 150.176 177.473 1.00 75.46  ? 246 MET C O   1 
ATOM 1728 C CB  . MET A 1 246 ? 146.876 150.239 180.535 1.00 75.46  ? 246 MET C CB  1 
ATOM 1729 C CG  . MET A 1 246 ? 146.182 151.426 181.184 1.00 75.46  ? 246 MET C CG  1 
ATOM 1730 S SD  . MET A 1 246 ? 146.193 151.351 182.985 1.00 75.46  ? 246 MET C SD  1 
ATOM 1731 C CE  . MET A 1 246 ? 146.200 149.581 183.255 1.00 75.46  ? 246 MET C CE  1 
ATOM 1732 N N   . ASN A 1 247 ? 148.450 151.994 178.769 1.00 59.07  ? 247 ASN C N   1 
ATOM 1733 C CA  . ASN A 1 247 ? 149.663 152.630 178.251 1.00 59.07  ? 247 ASN C CA  1 
ATOM 1734 C C   . ASN A 1 247 ? 150.841 152.322 179.179 1.00 59.07  ? 247 ASN C C   1 
ATOM 1735 O O   . ASN A 1 247 ? 151.528 153.200 179.702 1.00 59.07  ? 247 ASN C O   1 
ATOM 1736 C CB  . ASN A 1 247 ? 149.439 154.127 178.074 1.00 59.07  ? 247 ASN C CB  1 
ATOM 1737 C CG  . ASN A 1 247 ? 149.205 154.847 179.390 1.00 59.07  ? 247 ASN C CG  1 
ATOM 1738 O OD1 . ASN A 1 247 ? 148.775 154.245 180.373 1.00 59.07  ? 247 ASN C OD1 1 
ATOM 1739 N ND2 . ASN A 1 247 ? 149.488 156.144 179.413 1.00 59.07  ? 247 ASN C ND2 1 
ATOM 1740 N N   . ILE A 1 248 ? 151.076 151.024 179.361 1.00 49.60  ? 248 ILE C N   1 
ATOM 1741 C CA  . ILE A 1 248 ? 152.112 150.539 180.265 1.00 49.60  ? 248 ILE C CA  1 
ATOM 1742 C C   . ILE A 1 248 ? 153.097 149.664 179.501 1.00 49.60  ? 248 ILE C C   1 
ATOM 1743 O O   . ILE A 1 248 ? 152.849 149.291 178.349 1.00 49.60  ? 248 ILE C O   1 
ATOM 1744 C CB  . ILE A 1 248 ? 151.493 149.768 181.442 1.00 49.60  ? 248 ILE C CB  1 
ATOM 1745 C CG1 . ILE A 1 248 ? 150.998 148.402 180.973 1.00 49.60  ? 248 ILE C CG1 1 
ATOM 1746 C CG2 . ILE A 1 248 ? 150.357 150.559 182.060 1.00 49.60  ? 248 ILE C CG2 1 
ATOM 1747 C CD1 . ILE A 1 248 ? 150.660 147.463 182.101 1.00 49.60  ? 248 ILE C CD1 1 
ATOM 1748 N N   . ILE A 1 249 ? 154.218 149.329 180.138 1.00 39.97  ? 249 ILE C N   1 
ATOM 1749 C CA  . ILE A 1 249 ? 155.230 148.452 179.554 1.00 39.97  ? 249 ILE C CA  1 
ATOM 1750 C C   . ILE A 1 249 ? 155.219 147.156 180.347 1.00 39.97  ? 249 ILE C C   1 
ATOM 1751 O O   . ILE A 1 249 ? 155.399 147.173 181.569 1.00 39.97  ? 249 ILE C O   1 
ATOM 1752 C CB  . ILE A 1 249 ? 156.646 149.053 179.563 1.00 39.97  ? 249 ILE C CB  1 
ATOM 1753 C CG1 . ILE A 1 249 ? 156.789 150.220 178.587 1.00 39.97  ? 249 ILE C CG1 1 
ATOM 1754 C CG2 . ILE A 1 249 ? 157.674 147.981 179.265 1.00 39.97  ? 249 ILE C CG2 1 
ATOM 1755 C CD1 . ILE A 1 249 ? 156.093 151.462 179.005 1.00 39.97  ? 249 ILE C CD1 1 
ATOM 1756 N N   . LEU A 1 250 ? 155.020 146.040 179.663 1.00 37.18  ? 250 LEU C N   1 
ATOM 1757 C CA  . LEU A 1 250 ? 155.207 144.748 180.292 1.00 37.18  ? 250 LEU C CA  1 
ATOM 1758 C C   . LEU A 1 250 ? 156.628 144.253 180.049 1.00 37.18  ? 250 LEU C C   1 
ATOM 1759 O O   . LEU A 1 250 ? 157.275 144.596 179.058 1.00 37.18  ? 250 LEU C O   1 
ATOM 1760 C CB  . LEU A 1 250 ? 154.191 143.740 179.771 1.00 37.18  ? 250 LEU C CB  1 
ATOM 1761 C CG  . LEU A 1 250 ? 152.895 143.702 180.571 1.00 37.18  ? 250 LEU C CG  1 
ATOM 1762 C CD1 . LEU A 1 250 ? 151.905 144.720 180.041 1.00 37.18  ? 250 LEU C CD1 1 
ATOM 1763 C CD2 . LEU A 1 250 ? 152.320 142.315 180.543 1.00 37.18  ? 250 LEU C CD2 1 
ATOM 1764 N N   . ALA A 1 251 ? 157.114 143.437 180.977 1.00 37.46  ? 251 ALA C N   1 
ATOM 1765 C CA  . ALA A 1 251 ? 158.462 142.900 180.892 1.00 37.46  ? 251 ALA C CA  1 
ATOM 1766 C C   . ALA A 1 251 ? 158.564 141.730 181.856 1.00 37.46  ? 251 ALA C C   1 
ATOM 1767 O O   . ALA A 1 251 ? 157.970 141.743 182.937 1.00 37.46  ? 251 ALA C O   1 
ATOM 1768 C CB  . ALA A 1 251 ? 159.516 143.959 181.218 1.00 37.46  ? 251 ALA C CB  1 
ATOM 1769 N N   . GLY A 1 252 ? 159.315 140.721 181.451 1.00 52.44  ? 252 GLY C N   1 
ATOM 1770 C CA  . GLY A 1 252 ? 159.538 139.561 182.284 1.00 52.44  ? 252 GLY C CA  1 
ATOM 1771 C C   . GLY A 1 252 ? 159.221 138.290 181.524 1.00 52.44  ? 252 GLY C C   1 
ATOM 1772 O O   . GLY A 1 252 ? 159.176 138.280 180.299 1.00 52.44  ? 252 GLY C O   1 
ATOM 1773 N N   . GLY A 1 253 ? 158.992 137.228 182.286 1.00 58.62  ? 253 GLY C N   1 
ATOM 1774 C CA  . GLY A 1 253 ? 158.746 135.928 181.699 1.00 58.62  ? 253 GLY C CA  1 
ATOM 1775 C C   . GLY A 1 253 ? 158.438 134.910 182.778 1.00 58.62  ? 253 GLY C C   1 
ATOM 1776 O O   . GLY A 1 253 ? 157.932 135.247 183.850 1.00 58.62  ? 253 GLY C O   1 
ATOM 1777 N N   . GLN A 1 254 ? 158.749 133.657 182.467 1.00 63.83  ? 254 GLN C N   1 
ATOM 1778 C CA  . GLN A 1 254 ? 158.496 132.542 183.366 1.00 63.83  ? 254 GLN C CA  1 
ATOM 1779 C C   . GLN A 1 254 ? 159.788 132.110 184.047 1.00 63.83  ? 254 GLN C C   1 
ATOM 1780 O O   . GLN A 1 254 ? 160.844 132.042 183.413 1.00 63.83  ? 254 GLN C O   1 
ATOM 1781 C CB  . GLN A 1 254 ? 157.882 131.365 182.609 1.00 63.83  ? 254 GLN C CB  1 
ATOM 1782 C CG  . GLN A 1 254 ? 156.639 131.728 181.823 1.00 63.83  ? 254 GLN C CG  1 
ATOM 1783 C CD  . GLN A 1 254 ? 155.982 130.523 181.188 1.00 63.83  ? 254 GLN C CD  1 
ATOM 1784 O OE1 . GLN A 1 254 ? 156.397 129.386 181.412 1.00 63.83  ? 254 GLN C OE1 1 
ATOM 1785 N NE2 . GLN A 1 254 ? 154.956 130.764 180.382 1.00 63.83  ? 254 GLN C NE2 1 
ATOM 1786 N N   . VAL A 1 255 ? 159.696 131.825 185.346 1.00 63.59  ? 255 VAL C N   1 
ATOM 1787 C CA  . VAL A 1 255 ? 160.856 131.442 186.145 1.00 63.59  ? 255 VAL C CA  1 
ATOM 1788 C C   . VAL A 1 255 ? 160.551 130.145 186.884 1.00 63.59  ? 255 VAL C C   1 
ATOM 1789 O O   . VAL A 1 255 ? 159.481 129.555 186.702 1.00 63.59  ? 255 VAL C O   1 
ATOM 1790 C CB  . VAL A 1 255 ? 161.249 132.563 187.124 1.00 63.59  ? 255 VAL C CB  1 
ATOM 1791 C CG1 . VAL A 1 255 ? 161.366 133.884 186.387 1.00 63.59  ? 255 VAL C CG1 1 
ATOM 1792 C CG2 . VAL A 1 255 ? 160.236 132.664 188.251 1.00 63.59  ? 255 VAL C CG2 1 
ATOM 1793 N N   . ASP A 1 256 ? 161.487 129.689 187.720 1.00 72.11  ? 256 ASP C N   1 
ATOM 1794 C CA  . ASP A 1 256 ? 161.319 128.398 188.382 1.00 72.11  ? 256 ASP C CA  1 
ATOM 1795 C C   . ASP A 1 256 ? 160.376 128.489 189.575 1.00 72.11  ? 256 ASP C C   1 
ATOM 1796 O O   . ASP A 1 256 ? 159.305 127.874 189.581 1.00 72.11  ? 256 ASP C O   1 
ATOM 1797 C CB  . ASP A 1 256 ? 162.674 127.850 188.835 1.00 72.11  ? 256 ASP C CB  1 
ATOM 1798 C CG  . ASP A 1 256 ? 163.753 128.019 187.794 1.00 72.11  ? 256 ASP C CG  1 
ATOM 1799 O OD1 . ASP A 1 256 ? 163.505 127.684 186.617 1.00 72.11  ? 256 ASP C OD1 1 
ATOM 1800 O OD2 . ASP A 1 256 ? 164.852 128.484 188.158 1.00 72.11  ? 256 ASP C OD2 1 
ATOM 1801 N N   . ASN A 1 257 ? 160.755 129.253 190.596 1.00 73.09  ? 257 ASN C N   1 
ATOM 1802 C CA  . ASN A 1 257 ? 160.020 129.233 191.852 1.00 73.09  ? 257 ASN C CA  1 
ATOM 1803 C C   . ASN A 1 257 ? 160.275 130.528 192.608 1.00 73.09  ? 257 ASN C C   1 
ATOM 1804 O O   . ASN A 1 257 ? 161.103 131.352 192.213 1.00 73.09  ? 257 ASN C O   1 
ATOM 1805 C CB  . ASN A 1 257 ? 160.410 128.020 192.700 1.00 73.09  ? 257 ASN C CB  1 
ATOM 1806 C CG  . ASN A 1 257 ? 159.208 127.303 193.277 1.00 73.09  ? 257 ASN C CG  1 
ATOM 1807 O OD1 . ASN A 1 257 ? 158.149 127.899 193.472 1.00 73.09  ? 257 ASN C OD1 1 
ATOM 1808 N ND2 . ASN A 1 257 ? 159.363 126.012 193.545 1.00 73.09  ? 257 ASN C ND2 1 
ATOM 1809 N N   . LEU A 1 258 ? 159.547 130.690 193.710 1.00 71.27  ? 258 LEU C N   1 
ATOM 1810 C CA  . LEU A 1 258 ? 159.621 131.875 194.550 1.00 71.27  ? 258 LEU C CA  1 
ATOM 1811 C C   . LEU A 1 258 ? 160.349 131.529 195.840 1.00 71.27  ? 258 LEU C C   1 
ATOM 1812 O O   . LEU A 1 258 ? 160.340 130.373 196.275 1.00 71.27  ? 258 LEU C O   1 
ATOM 1813 C CB  . LEU A 1 258 ? 158.226 132.408 194.878 1.00 71.27  ? 258 LEU C CB  1 
ATOM 1814 C CG  . LEU A 1 258 ? 157.561 133.318 193.846 1.00 71.27  ? 258 LEU C CG  1 
ATOM 1815 C CD1 . LEU A 1 258 ? 156.441 134.110 194.497 1.00 71.27  ? 258 LEU C CD1 1 
ATOM 1816 C CD2 . LEU A 1 258 ? 158.564 134.231 193.171 1.00 71.27  ? 258 LEU C CD2 1 
ATOM 1817 N N   . SER A 1 259 ? 160.977 132.530 196.453 1.00 73.18  ? 259 SER C N   1 
ATOM 1818 C CA  . SER A 1 259 ? 161.723 132.314 197.687 1.00 73.18  ? 259 SER C CA  1 
ATOM 1819 C C   . SER A 1 259 ? 161.146 133.080 198.872 1.00 73.18  ? 259 SER C C   1 
ATOM 1820 O O   . SER A 1 259 ? 160.909 132.489 199.929 1.00 73.18  ? 259 SER C O   1 
ATOM 1821 C CB  . SER A 1 259 ? 163.196 132.692 197.488 1.00 73.18  ? 259 SER C CB  1 
ATOM 1822 O OG  . SER A 1 259 ? 163.378 134.095 197.532 1.00 73.18  ? 259 SER C OG  1 
ATOM 1823 N N   . SER A 1 260 ? 160.910 134.383 198.723 1.00 75.83  ? 260 SER C N   1 
ATOM 1824 C CA  . SER A 1 260 ? 160.467 135.192 199.851 1.00 75.83  ? 260 SER C CA  1 
ATOM 1825 C C   . SER A 1 260 ? 159.652 136.381 199.367 1.00 75.83  ? 260 SER C C   1 
ATOM 1826 O O   . SER A 1 260 ? 160.065 137.087 198.443 1.00 75.83  ? 260 SER C O   1 
ATOM 1827 C CB  . SER A 1 260 ? 161.665 135.680 200.672 1.00 75.83  ? 260 SER C CB  1 
ATOM 1828 O OG  . SER A 1 260 ? 162.478 136.553 199.909 1.00 75.83  ? 260 SER C OG  1 
ATOM 1829 N N   . LEU A 1 261 ? 158.499 136.596 199.997 1.00 75.04  ? 261 LEU C N   1 
ATOM 1830 C CA  . LEU A 1 261 ? 157.681 137.781 199.781 1.00 75.04  ? 261 LEU C CA  1 
ATOM 1831 C C   . LEU A 1 261 ? 157.241 138.327 201.131 1.00 75.04  ? 261 LEU C C   1 
ATOM 1832 O O   . LEU A 1 261 ? 156.875 137.562 202.028 1.00 75.04  ? 261 LEU C O   1 
ATOM 1833 C CB  . LEU A 1 261 ? 156.459 137.470 198.912 1.00 75.04  ? 261 LEU C CB  1 
ATOM 1834 C CG  . LEU A 1 261 ? 155.788 138.658 198.220 1.00 75.04  ? 261 LEU C CG  1 
ATOM 1835 C CD1 . LEU A 1 261 ? 156.818 139.599 197.628 1.00 75.04  ? 261 LEU C CD1 1 
ATOM 1836 C CD2 . LEU A 1 261 ? 154.834 138.173 197.148 1.00 75.04  ? 261 LEU C CD2 1 
ATOM 1837 N N   . THR A 1 262 ? 157.276 139.653 201.272 1.00 84.03  ? 262 THR C N   1 
ATOM 1838 C CA  . THR A 1 262 ? 156.943 140.301 202.541 1.00 84.03  ? 262 THR C CA  1 
ATOM 1839 C C   . THR A 1 262 ? 155.492 140.770 202.503 1.00 84.03  ? 262 THR C C   1 
ATOM 1840 O O   . THR A 1 262 ? 155.179 141.933 202.236 1.00 84.03  ? 262 THR C O   1 
ATOM 1841 C CB  . THR A 1 262 ? 157.899 141.451 202.828 1.00 84.03  ? 262 THR C CB  1 
ATOM 1842 O OG1 . THR A 1 262 ? 157.867 142.387 201.743 1.00 84.03  ? 262 THR C OG1 1 
ATOM 1843 C CG2 . THR A 1 262 ? 159.315 140.932 203.010 1.00 84.03  ? 262 THR C CG2 1 
ATOM 1844 N N   . SER A 1 263 ? 154.588 139.831 202.779 1.00 112.46 ? 263 SER C N   1 
ATOM 1845 C CA  . SER A 1 263 ? 153.178 140.136 202.953 1.00 112.46 ? 263 SER C CA  1 
ATOM 1846 C C   . SER A 1 263 ? 152.694 139.932 204.381 1.00 112.46 ? 263 SER C C   1 
ATOM 1847 O O   . SER A 1 263 ? 151.613 140.426 204.724 1.00 112.46 ? 263 SER C O   1 
ATOM 1848 C CB  . SER A 1 263 ? 152.322 139.285 202.003 1.00 112.46 ? 263 SER C CB  1 
ATOM 1849 O OG  . SER A 1 263 ? 152.488 137.906 202.273 1.00 112.46 ? 263 SER C OG  1 
ATOM 1850 N N   . GLU A 1 264 ? 153.454 139.217 205.214 1.00 133.08 ? 264 GLU C N   1 
ATOM 1851 C CA  . GLU A 1 264 ? 153.190 139.054 206.643 1.00 133.08 ? 264 GLU C CA  1 
ATOM 1852 C C   . GLU A 1 264 ? 151.859 138.365 206.929 1.00 133.08 ? 264 GLU C C   1 
ATOM 1853 O O   . GLU A 1 264 ? 151.333 138.468 208.042 1.00 133.08 ? 264 GLU C O   1 
ATOM 1854 C CB  . GLU A 1 264 ? 153.250 140.402 207.374 1.00 133.08 ? 264 GLU C CB  1 
ATOM 1855 C CG  . GLU A 1 264 ? 154.645 140.800 207.831 1.00 133.08 ? 264 GLU C CG  1 
ATOM 1856 C CD  . GLU A 1 264 ? 154.637 142.014 208.740 1.00 133.08 ? 264 GLU C CD  1 
ATOM 1857 O OE1 . GLU A 1 264 ? 153.560 142.624 208.910 1.00 133.08 ? 264 GLU C OE1 1 
ATOM 1858 O OE2 . GLU A 1 264 ? 155.707 142.359 209.283 1.00 133.08 ? 264 GLU C OE2 1 
ATOM 1859 N N   . LYS A 1 265 ? 151.293 137.654 205.948 1.00 134.99 ? 265 LYS C N   1 
ATOM 1860 C CA  . LYS A 1 265 ? 150.033 136.958 206.181 1.00 134.99 ? 265 LYS C CA  1 
ATOM 1861 C C   . LYS A 1 265 ? 149.979 135.588 205.510 1.00 134.99 ? 265 LYS C C   1 
ATOM 1862 O O   . LYS A 1 265 ? 148.899 134.990 205.438 1.00 134.99 ? 265 LYS C O   1 
ATOM 1863 C CB  . LYS A 1 265 ? 148.846 137.806 205.705 1.00 134.99 ? 265 LYS C CB  1 
ATOM 1864 C CG  . LYS A 1 265 ? 148.390 138.850 206.712 1.00 134.99 ? 265 LYS C CG  1 
ATOM 1865 C CD  . LYS A 1 265 ? 147.262 139.704 206.160 1.00 134.99 ? 265 LYS C CD  1 
ATOM 1866 C CE  . LYS A 1 265 ? 146.845 140.774 207.156 1.00 134.99 ? 265 LYS C CE  1 
ATOM 1867 N NZ  . LYS A 1 265 ? 145.859 141.726 206.574 1.00 134.99 ? 265 LYS C NZ  1 
ATOM 1868 N N   . ASN A 1 266 ? 151.104 135.072 205.020 1.00 123.35 ? 266 ASN C N   1 
ATOM 1869 C CA  . ASN A 1 266 ? 151.074 133.781 204.345 1.00 123.35 ? 266 ASN C CA  1 
ATOM 1870 C C   . ASN A 1 266 ? 152.430 133.086 204.387 1.00 123.35 ? 266 ASN C C   1 
ATOM 1871 O O   . ASN A 1 266 ? 153.415 133.605 203.846 1.00 123.35 ? 266 ASN C O   1 
ATOM 1872 C CB  . ASN A 1 266 ? 150.617 133.950 202.893 1.00 123.35 ? 266 ASN C CB  1 
ATOM 1873 C CG  . ASN A 1 266 ? 151.329 135.087 202.184 1.00 123.35 ? 266 ASN C CG  1 
ATOM 1874 O OD1 . ASN A 1 266 ? 152.138 135.797 202.780 1.00 123.35 ? 266 ASN C OD1 1 
ATOM 1875 N ND2 . ASN A 1 266 ? 151.033 135.261 200.901 1.00 123.35 ? 266 ASN C ND2 1 
ATOM 1876 N N   . PRO A 1 267 ? 152.527 131.920 205.022 1.00 111.00 ? 267 PRO C N   1 
ATOM 1877 C CA  . PRO A 1 267 ? 153.736 131.097 204.864 1.00 111.00 ? 267 PRO C CA  1 
ATOM 1878 C C   . PRO A 1 267 ? 153.806 130.559 203.444 1.00 111.00 ? 267 PRO C C   1 
ATOM 1879 O O   . PRO A 1 267 ? 152.901 129.862 202.980 1.00 111.00 ? 267 PRO C O   1 
ATOM 1880 C CB  . PRO A 1 267 ? 153.557 129.976 205.896 1.00 111.00 ? 267 PRO C CB  1 
ATOM 1881 C CG  . PRO A 1 267 ? 152.156 130.053 206.375 1.00 111.00 ? 267 PRO C CG  1 
ATOM 1882 C CD  . PRO A 1 267 ? 151.523 131.322 205.917 1.00 111.00 ? 267 PRO C CD  1 
ATOM 1883 N N   . LEU A 1 268 ? 154.892 130.895 202.751 1.00 100.76 ? 268 LEU C N   1 
ATOM 1884 C CA  . LEU A 1 268 ? 154.984 130.650 201.316 1.00 100.76 ? 268 LEU C CA  1 
ATOM 1885 C C   . LEU A 1 268 ? 154.965 129.153 201.024 1.00 100.76 ? 268 LEU C C   1 
ATOM 1886 O O   . LEU A 1 268 ? 155.682 128.376 201.663 1.00 100.76 ? 268 LEU C O   1 
ATOM 1887 C CB  . LEU A 1 268 ? 156.250 131.296 200.759 1.00 100.76 ? 268 LEU C CB  1 
ATOM 1888 C CG  . LEU A 1 268 ? 156.311 131.519 199.246 1.00 100.76 ? 268 LEU C CG  1 
ATOM 1889 C CD1 . LEU A 1 268 ? 157.085 132.790 198.940 1.00 100.76 ? 268 LEU C CD1 1 
ATOM 1890 C CD2 . LEU A 1 268 ? 156.938 130.330 198.535 1.00 100.76 ? 268 LEU C CD2 1 
ATOM 1891 N N   . ASP A 1 269 ? 154.142 128.754 200.057 1.00 106.71 ? 269 ASP C N   1 
ATOM 1892 C CA  . ASP A 1 269 ? 154.046 127.360 199.635 1.00 106.71 ? 269 ASP C CA  1 
ATOM 1893 C C   . ASP A 1 269 ? 154.904 127.167 198.391 1.00 106.71 ? 269 ASP C C   1 
ATOM 1894 O O   . ASP A 1 269 ? 154.714 127.855 197.383 1.00 106.71 ? 269 ASP C O   1 
ATOM 1895 C CB  . ASP A 1 269 ? 152.591 126.985 199.368 1.00 106.71 ? 269 ASP C CB  1 
ATOM 1896 C CG  . ASP A 1 269 ? 152.383 125.486 199.267 1.00 106.71 ? 269 ASP C CG  1 
ATOM 1897 O OD1 . ASP A 1 269 ? 153.375 124.735 199.376 1.00 106.71 ? 269 ASP C OD1 1 
ATOM 1898 O OD2 . ASP A 1 269 ? 151.224 125.059 199.079 1.00 106.71 ? 269 ASP C OD2 1 
ATOM 1899 N N   . ILE A 1 270 ? 155.852 126.230 198.458 1.00 94.69  ? 270 ILE C N   1 
ATOM 1900 C CA  . ILE A 1 270 ? 156.805 126.065 197.365 1.00 94.69  ? 270 ILE C CA  1 
ATOM 1901 C C   . ILE A 1 270 ? 156.160 125.376 196.166 1.00 94.69  ? 270 ILE C C   1 
ATOM 1902 O O   . ILE A 1 270 ? 156.599 125.565 195.025 1.00 94.69  ? 270 ILE C O   1 
ATOM 1903 C CB  . ILE A 1 270 ? 158.049 125.302 197.860 1.00 94.69  ? 270 ILE C CB  1 
ATOM 1904 C CG1 . ILE A 1 270 ? 159.198 125.443 196.861 1.00 94.69  ? 270 ILE C CG1 1 
ATOM 1905 C CG2 . ILE A 1 270 ? 157.728 123.837 198.107 1.00 94.69  ? 270 ILE C CG2 1 
ATOM 1906 C CD1 . ILE A 1 270 ? 159.713 126.856 196.735 1.00 94.69  ? 270 ILE C CD1 1 
ATOM 1907 N N   . ASP A 1 271 ? 155.116 124.576 196.390 1.00 96.30  ? 271 ASP C N   1 
ATOM 1908 C CA  . ASP A 1 271 ? 154.520 123.792 195.315 1.00 96.30  ? 271 ASP C CA  1 
ATOM 1909 C C   . ASP A 1 271 ? 153.506 124.567 194.484 1.00 96.30  ? 271 ASP C C   1 
ATOM 1910 O O   . ASP A 1 271 ? 153.146 124.108 193.395 1.00 96.30  ? 271 ASP C O   1 
ATOM 1911 C CB  . ASP A 1 271 ? 153.851 122.542 195.888 1.00 96.30  ? 271 ASP C CB  1 
ATOM 1912 C CG  . ASP A 1 271 ? 154.848 121.567 196.477 1.00 96.30  ? 271 ASP C CG  1 
ATOM 1913 O OD1 . ASP A 1 271 ? 155.207 121.727 197.663 1.00 96.30  ? 271 ASP C OD1 1 
ATOM 1914 O OD2 . ASP A 1 271 ? 155.274 120.643 195.754 1.00 96.30  ? 271 ASP C OD2 1 
ATOM 1915 N N   . ALA A 1 272 ? 153.040 125.718 194.955 1.00 91.90  ? 272 ALA C N   1 
ATOM 1916 C CA  . ALA A 1 272 ? 151.981 126.447 194.276 1.00 91.90  ? 272 ALA C CA  1 
ATOM 1917 C C   . ALA A 1 272 ? 152.555 127.442 193.275 1.00 91.90  ? 272 ALA C C   1 
ATOM 1918 O O   . ALA A 1 272 ? 153.607 128.044 193.500 1.00 91.90  ? 272 ALA C O   1 
ATOM 1919 C CB  . ALA A 1 272 ? 151.096 127.176 195.288 1.00 91.90  ? 272 ALA C CB  1 
ATOM 1920 N N   . SER A 1 273 ? 151.848 127.606 192.162 1.00 80.27  ? 273 SER C N   1 
ATOM 1921 C CA  . SER A 1 273 ? 152.243 128.537 191.117 1.00 80.27  ? 273 SER C CA  1 
ATOM 1922 C C   . SER A 1 273 ? 151.464 129.840 191.240 1.00 80.27  ? 273 SER C C   1 
ATOM 1923 O O   . SER A 1 273 ? 150.457 129.928 191.946 1.00 80.27  ? 273 SER C O   1 
ATOM 1924 C CB  . SER A 1 273 ? 152.017 127.926 189.735 1.00 80.27  ? 273 SER C CB  1 
ATOM 1925 O OG  . SER A 1 273 ? 150.656 127.591 189.544 1.00 80.27  ? 273 SER C OG  1 
ATOM 1926 N N   . GLY A 1 274 ? 151.943 130.859 190.538 1.00 67.25  ? 274 GLY C N   1 
ATOM 1927 C CA  . GLY A 1 274 ? 151.288 132.153 190.585 1.00 67.25  ? 274 GLY C CA  1 
ATOM 1928 C C   . GLY A 1 274 ? 152.043 133.168 189.760 1.00 67.25  ? 274 GLY C C   1 
ATOM 1929 O O   . GLY A 1 274 ? 152.968 132.837 189.011 1.00 67.25  ? 274 GLY C O   1 
ATOM 1930 N N   . VAL A 1 275 ? 151.629 134.422 189.912 1.00 56.14  ? 275 VAL C N   1 
ATOM 1931 C CA  . VAL A 1 275 ? 152.208 135.550 189.192 1.00 56.14  ? 275 VAL C CA  1 
ATOM 1932 C C   . VAL A 1 275 ? 152.626 136.592 190.219 1.00 56.14  ? 275 VAL C C   1 
ATOM 1933 O O   . VAL A 1 275 ? 151.822 136.990 191.072 1.00 56.14  ? 275 VAL C O   1 
ATOM 1934 C CB  . VAL A 1 275 ? 151.225 136.142 188.176 1.00 56.14  ? 275 VAL C CB  1 
ATOM 1935 C CG1 . VAL A 1 275 ? 151.867 137.286 187.427 1.00 56.14  ? 275 VAL C CG1 1 
ATOM 1936 C CG2 . VAL A 1 275 ? 150.769 135.067 187.213 1.00 56.14  ? 275 VAL C CG2 1 
ATOM 1937 N N   . VAL A 1 276 ? 153.879 137.032 190.143 1.00 51.48  ? 276 VAL C N   1 
ATOM 1938 C CA  . VAL A 1 276 ? 154.426 138.040 191.042 1.00 51.48  ? 276 VAL C CA  1 
ATOM 1939 C C   . VAL A 1 276 ? 155.224 139.041 190.223 1.00 51.48  ? 276 VAL C C   1 
ATOM 1940 O O   . VAL A 1 276 ? 155.634 138.747 189.096 1.00 51.48  ? 276 VAL C O   1 
ATOM 1941 C CB  . VAL A 1 276 ? 155.314 137.411 192.131 1.00 51.48  ? 276 VAL C CB  1 
ATOM 1942 C CG1 . VAL A 1 276 ? 154.460 136.823 193.228 1.00 51.48  ? 276 VAL C CG1 1 
ATOM 1943 C CG2 . VAL A 1 276 ? 156.202 136.350 191.522 1.00 51.48  ? 276 VAL C CG2 1 
ATOM 1944 N N   . GLY A 1 277 ? 155.441 140.221 190.790 1.00 44.30  ? 277 GLY C N   1 
ATOM 1945 C CA  . GLY A 1 277 ? 156.261 141.213 190.120 1.00 44.30  ? 277 GLY C CA  1 
ATOM 1946 C C   . GLY A 1 277 ? 156.136 142.561 190.790 1.00 44.30  ? 277 GLY C C   1 
ATOM 1947 O O   . GLY A 1 277 ? 155.414 142.729 191.776 1.00 44.30  ? 277 GLY C O   1 
ATOM 1948 N N   . LEU A 1 278 ? 156.857 143.527 190.233 1.00 39.36  ? 278 LEU C N   1 
ATOM 1949 C CA  . LEU A 1 278 ? 156.808 144.906 190.683 1.00 39.36  ? 278 LEU C CA  1 
ATOM 1950 C C   . LEU A 1 278 ? 155.895 145.705 189.764 1.00 39.36  ? 278 LEU C C   1 
ATOM 1951 O O   . LEU A 1 278 ? 155.688 145.353 188.601 1.00 39.36  ? 278 LEU C O   1 
ATOM 1952 C CB  . LEU A 1 278 ? 158.204 145.541 190.714 1.00 39.36  ? 278 LEU C CB  1 
ATOM 1953 C CG  . LEU A 1 278 ? 158.978 145.489 192.033 1.00 39.36  ? 278 LEU C CG  1 
ATOM 1954 C CD1 . LEU A 1 278 ? 159.101 144.068 192.547 1.00 39.36  ? 278 LEU C CD1 1 
ATOM 1955 C CD2 . LEU A 1 278 ? 160.349 146.125 191.873 1.00 39.36  ? 278 LEU C CD2 1 
ATOM 1956 N N   . SER A 1 279 ? 155.342 146.787 190.304 1.00 40.10  ? 279 SER C N   1 
ATOM 1957 C CA  . SER A 1 279 ? 154.444 147.668 189.561 1.00 40.10  ? 279 SER C CA  1 
ATOM 1958 C C   . SER A 1 279 ? 154.920 149.104 189.752 1.00 40.10  ? 279 SER C C   1 
ATOM 1959 O O   . SER A 1 279 ? 154.468 149.796 190.668 1.00 40.10  ? 279 SER C O   1 
ATOM 1960 C CB  . SER A 1 279 ? 153.003 147.499 190.024 1.00 40.10  ? 279 SER C CB  1 
ATOM 1961 O OG  . SER A 1 279 ? 152.749 148.292 191.169 1.00 40.10  ? 279 SER C OG  1 
ATOM 1962 N N   . PHE A 1 280 ? 155.827 149.546 188.888 1.00 35.36  ? 280 PHE C N   1 
ATOM 1963 C CA  . PHE A 1 280 ? 156.339 150.906 188.955 1.00 35.36  ? 280 PHE C CA  1 
ATOM 1964 C C   . PHE A 1 280 ? 155.222 151.900 188.674 1.00 35.36  ? 280 PHE C C   1 
ATOM 1965 O O   . PHE A 1 280 ? 154.352 151.657 187.835 1.00 35.36  ? 280 PHE C O   1 
ATOM 1966 C CB  . PHE A 1 280 ? 157.476 151.109 187.952 1.00 35.36  ? 280 PHE C CB  1 
ATOM 1967 C CG  . PHE A 1 280 ? 158.759 150.421 188.329 1.00 35.36  ? 280 PHE C CG  1 
ATOM 1968 C CD1 . PHE A 1 280 ? 158.781 149.076 188.656 1.00 35.36  ? 280 PHE C CD1 1 
ATOM 1969 C CD2 . PHE A 1 280 ? 159.949 151.123 188.343 1.00 35.36  ? 280 PHE C CD2 1 
ATOM 1970 C CE1 . PHE A 1 280 ? 159.958 148.451 188.996 1.00 35.36  ? 280 PHE C CE1 1 
ATOM 1971 C CE2 . PHE A 1 280 ? 161.129 150.502 188.682 1.00 35.36  ? 280 PHE C CE2 1 
ATOM 1972 C CZ  . PHE A 1 280 ? 161.133 149.163 189.009 1.00 35.36  ? 280 PHE C CZ  1 
ATOM 1973 N N   . SER A 1 281 ? 155.246 153.023 189.386 1.00 46.75  ? 281 SER C N   1 
ATOM 1974 C CA  . SER A 1 281 ? 154.224 154.044 189.226 1.00 46.75  ? 281 SER C CA  1 
ATOM 1975 C C   . SER A 1 281 ? 154.808 155.395 189.601 1.00 46.75  ? 281 SER C C   1 
ATOM 1976 O O   . SER A 1 281 ? 155.470 155.527 190.633 1.00 46.75  ? 281 SER C O   1 
ATOM 1977 C CB  . SER A 1 281 ? 152.994 153.741 190.086 1.00 46.75  ? 281 SER C CB  1 
ATOM 1978 O OG  . SER A 1 281 ? 153.375 153.339 191.390 1.00 46.75  ? 281 SER C OG  1 
ATOM 1979 N N   . GLY A 1 282 ? 154.558 156.389 188.760 1.00 54.36  ? 282 GLY C N   1 
ATOM 1980 C CA  . GLY A 1 282 ? 155.080 157.715 189.015 1.00 54.36  ? 282 GLY C CA  1 
ATOM 1981 C C   . GLY A 1 282 ? 154.726 158.653 187.888 1.00 54.36  ? 282 GLY C C   1 
ATOM 1982 O O   . GLY A 1 282 ? 153.966 158.301 186.985 1.00 54.36  ? 282 GLY C O   1 
ATOM 1983 N N   . HIS A 1 283 ? 155.291 159.858 187.946 1.00 61.26  ? 283 HIS C N   1 
ATOM 1984 C CA  . HIS A 1 283 ? 155.040 160.871 186.933 1.00 61.26  ? 283 HIS C CA  1 
ATOM 1985 C C   . HIS A 1 283 ? 156.214 161.103 185.995 1.00 61.26  ? 283 HIS C C   1 
ATOM 1986 O O   . HIS A 1 283 ? 156.025 161.743 184.955 1.00 61.26  ? 283 HIS C O   1 
ATOM 1987 C CB  . HIS A 1 283 ? 154.659 162.207 187.590 1.00 61.26  ? 283 HIS C CB  1 
ATOM 1988 C CG  . HIS A 1 283 ? 153.911 163.136 186.686 1.00 61.26  ? 283 HIS C CG  1 
ATOM 1989 N ND1 . HIS A 1 283 ? 154.035 163.104 185.313 1.00 61.26  ? 283 HIS C ND1 1 
ATOM 1990 C CD2 . HIS A 1 283 ? 153.030 164.128 186.959 1.00 61.26  ? 283 HIS C CD2 1 
ATOM 1991 C CE1 . HIS A 1 283 ? 153.263 164.033 184.780 1.00 61.26  ? 283 HIS C CE1 1 
ATOM 1992 N NE2 . HIS A 1 283 ? 152.642 164.669 185.757 1.00 61.26  ? 283 HIS C NE2 1 
ATOM 1993 N N   . ARG A 1 284 ? 157.408 160.610 186.318 1.00 59.04  ? 284 ARG C N   1 
ATOM 1994 C CA  . ARG A 1 284 ? 158.571 160.785 185.462 1.00 59.04  ? 284 ARG C CA  1 
ATOM 1995 C C   . ARG A 1 284 ? 159.204 159.471 185.034 1.00 59.04  ? 284 ARG C C   1 
ATOM 1996 O O   . ARG A 1 284 ? 160.285 159.490 184.436 1.00 59.04  ? 284 ARG C O   1 
ATOM 1997 C CB  . ARG A 1 284 ? 159.626 161.651 186.164 1.00 59.04  ? 284 ARG C CB  1 
ATOM 1998 C CG  . ARG A 1 284 ? 159.569 163.118 185.785 1.00 59.04  ? 284 ARG C CG  1 
ATOM 1999 C CD  . ARG A 1 284 ? 158.502 163.849 186.582 1.00 59.04  ? 284 ARG C CD  1 
ATOM 2000 N NE  . ARG A 1 284 ? 158.759 163.793 188.017 1.00 59.04  ? 284 ARG C NE  1 
ATOM 2001 C CZ  . ARG A 1 284 ? 159.699 164.491 188.640 1.00 59.04  ? 284 ARG C CZ  1 
ATOM 2002 N NH1 . ARG A 1 284 ? 160.488 165.327 187.985 1.00 59.04  ? 284 ARG C NH1 1 
ATOM 2003 N NH2 . ARG A 1 284 ? 159.848 164.350 189.954 1.00 59.04  ? 284 ARG C NH2 1 
ATOM 2004 N N   . ILE A 1 285 ? 158.568 158.335 185.312 1.00 45.40  ? 285 ILE C N   1 
ATOM 2005 C CA  . ILE A 1 285 ? 159.138 157.041 184.962 1.00 45.40  ? 285 ILE C CA  1 
ATOM 2006 C C   . ILE A 1 285 ? 159.005 156.817 183.464 1.00 45.40  ? 285 ILE C C   1 
ATOM 2007 O O   . ILE A 1 285 ? 157.943 156.419 182.975 1.00 45.40  ? 285 ILE C O   1 
ATOM 2008 C CB  . ILE A 1 285 ? 158.467 155.902 185.747 1.00 45.40  ? 285 ILE C CB  1 
ATOM 2009 C CG1 . ILE A 1 285 ? 158.632 156.120 187.249 1.00 45.40  ? 285 ILE C CG1 1 
ATOM 2010 C CG2 . ILE A 1 285 ? 159.050 154.563 185.346 1.00 45.40  ? 285 ILE C CG2 1 
ATOM 2011 C CD1 . ILE A 1 285 ? 157.924 155.084 188.088 1.00 45.40  ? 285 ILE C CD1 1 
ATOM 2012 N N   . GLN A 1 286 ? 160.078 157.074 182.729 1.00 39.51  ? 286 GLN C N   1 
ATOM 2013 C CA  . GLN A 1 286 ? 160.132 156.781 181.308 1.00 39.51  ? 286 GLN C CA  1 
ATOM 2014 C C   . GLN A 1 286 ? 160.574 155.338 181.094 1.00 39.51  ? 286 GLN C C   1 
ATOM 2015 O O   . GLN A 1 286 ? 161.184 154.715 181.966 1.00 39.51  ? 286 GLN C O   1 
ATOM 2016 C CB  . GLN A 1 286 ? 161.082 157.745 180.600 1.00 39.51  ? 286 GLN C CB  1 
ATOM 2017 C CG  . GLN A 1 286 ? 160.556 159.165 180.534 1.00 39.51  ? 286 GLN C CG  1 
ATOM 2018 C CD  . GLN A 1 286 ? 161.658 160.193 180.417 1.00 39.51  ? 286 GLN C CD  1 
ATOM 2019 O OE1 . GLN A 1 286 ? 162.149 160.472 179.325 1.00 39.51  ? 286 GLN C OE1 1 
ATOM 2020 N NE2 . GLN A 1 286 ? 162.051 160.768 181.546 1.00 39.51  ? 286 GLN C NE2 1 
ATOM 2021 N N   . SER A 1 287 ? 160.257 154.805 179.920 1.00 36.66  ? 287 SER C N   1 
ATOM 2022 C CA  . SER A 1 287 ? 160.508 153.397 179.648 1.00 36.66  ? 287 SER C CA  1 
ATOM 2023 C C   . SER A 1 287 ? 160.803 153.220 178.165 1.00 36.66  ? 287 SER C C   1 
ATOM 2024 O O   . SER A 1 287 ? 160.664 154.148 177.365 1.00 36.66  ? 287 SER C O   1 
ATOM 2025 C CB  . SER A 1 287 ? 159.324 152.536 180.084 1.00 36.66  ? 287 SER C CB  1 
ATOM 2026 O OG  . SER A 1 287 ? 159.660 151.161 180.068 1.00 36.66  ? 287 SER C OG  1 
ATOM 2027 N N   . ALA A 1 288 ? 161.217 152.007 177.812 1.00 38.84  ? 288 ALA C N   1 
ATOM 2028 C CA  . ALA A 1 288 ? 161.515 151.633 176.437 1.00 38.84  ? 288 ALA C CA  1 
ATOM 2029 C C   . ALA A 1 288 ? 161.632 150.119 176.380 1.00 38.84  ? 288 ALA C C   1 
ATOM 2030 O O   . ALA A 1 288 ? 161.993 149.473 177.366 1.00 38.84  ? 288 ALA C O   1 
ATOM 2031 C CB  . ALA A 1 288 ? 162.800 152.298 175.937 1.00 38.84  ? 288 ALA C CB  1 
ATOM 2032 N N   . THR A 1 289 ? 161.315 149.554 175.218 1.00 44.00  ? 289 THR C N   1 
ATOM 2033 C CA  . THR A 1 289 ? 161.337 148.106 175.073 1.00 44.00  ? 289 THR C CA  1 
ATOM 2034 C C   . THR A 1 289 ? 161.612 147.733 173.625 1.00 44.00  ? 289 THR C C   1 
ATOM 2035 O O   . THR A 1 289 ? 161.023 148.307 172.705 1.00 44.00  ? 289 THR C O   1 
ATOM 2036 C CB  . THR A 1 289 ? 160.015 147.481 175.525 1.00 44.00  ? 289 THR C CB  1 
ATOM 2037 O OG1 . THR A 1 289 ? 159.685 147.957 176.833 1.00 44.00  ? 289 THR C OG1 1 
ATOM 2038 C CG2 . THR A 1 289 ? 160.138 145.975 175.578 1.00 44.00  ? 289 THR C CG2 1 
ATOM 2039 N N   . VAL A 1 290 ? 162.508 146.766 173.432 1.00 45.09  ? 290 VAL C N   1 
ATOM 2040 C CA  . VAL A 1 290 ? 162.834 146.235 172.113 1.00 45.09  ? 290 VAL C CA  1 
ATOM 2041 C C   . VAL A 1 290 ? 162.786 144.717 172.180 1.00 45.09  ? 290 VAL C C   1 
ATOM 2042 O O   . VAL A 1 290 ? 163.388 144.113 173.074 1.00 45.09  ? 290 VAL C O   1 
ATOM 2043 C CB  . VAL A 1 290 ? 164.214 146.694 171.616 1.00 45.09  ? 290 VAL C CB  1 
ATOM 2044 C CG1 . VAL A 1 290 ? 164.520 146.060 170.276 1.00 45.09  ? 290 VAL C CG1 1 
ATOM 2045 C CG2 . VAL A 1 290 ? 164.247 148.194 171.482 1.00 45.09  ? 290 VAL C CG2 1 
ATOM 2046 N N   . LEU A 1 291 ? 162.072 144.103 171.244 1.00 45.36  ? 291 LEU C N   1 
ATOM 2047 C CA  . LEU A 1 291 ? 162.098 142.658 171.097 1.00 45.36  ? 291 LEU C CA  1 
ATOM 2048 C C   . LEU A 1 291 ? 163.290 142.237 170.248 1.00 45.36  ? 291 LEU C C   1 
ATOM 2049 O O   . LEU A 1 291 ? 163.704 142.945 169.326 1.00 45.36  ? 291 LEU C O   1 
ATOM 2050 C CB  . LEU A 1 291 ? 160.807 142.159 170.454 1.00 45.36  ? 291 LEU C CB  1 
ATOM 2051 C CG  . LEU A 1 291 ? 160.570 140.649 170.473 1.00 45.36  ? 291 LEU C CG  1 
ATOM 2052 C CD1 . LEU A 1 291 ? 160.747 140.087 171.871 1.00 45.36  ? 291 LEU C CD1 1 
ATOM 2053 C CD2 . LEU A 1 291 ? 159.200 140.312 169.914 1.00 45.36  ? 291 LEU C CD2 1 
ATOM 2054 N N   . LEU A 1 292 ? 163.846 141.075 170.571 1.00 54.84  ? 292 LEU C N   1 
ATOM 2055 C CA  . LEU A 1 292 ? 164.927 140.474 169.799 1.00 54.84  ? 292 LEU C CA  1 
ATOM 2056 C C   . LEU A 1 292 ? 164.427 139.141 169.264 1.00 54.84  ? 292 LEU C C   1 
ATOM 2057 O O   . LEU A 1 292 ? 164.591 138.104 169.915 1.00 54.84  ? 292 LEU C O   1 
ATOM 2058 C CB  . LEU A 1 292 ? 166.181 140.299 170.651 1.00 54.84  ? 292 LEU C CB  1 
ATOM 2059 C CG  . LEU A 1 292 ? 167.273 141.341 170.420 1.00 54.84  ? 292 LEU C CG  1 
ATOM 2060 C CD1 . LEU A 1 292 ? 166.815 142.701 170.903 1.00 54.84  ? 292 LEU C CD1 1 
ATOM 2061 C CD2 . LEU A 1 292 ? 168.551 140.933 171.125 1.00 54.84  ? 292 LEU C CD2 1 
ATOM 2062 N N   . ASN A 1 293 ? 163.823 139.170 168.079 1.00 66.70  ? 293 ASN C N   1 
ATOM 2063 C CA  . ASN A 1 293 ? 163.175 137.992 167.520 1.00 66.70  ? 293 ASN C CA  1 
ATOM 2064 C C   . ASN A 1 293 ? 164.198 137.041 166.915 1.00 66.70  ? 293 ASN C C   1 
ATOM 2065 O O   . ASN A 1 293 ? 165.403 137.194 167.133 1.00 66.70  ? 293 ASN C O   1 
ATOM 2066 C CB  . ASN A 1 293 ? 162.143 138.400 166.469 1.00 66.70  ? 293 ASN C CB  1 
ATOM 2067 C CG  . ASN A 1 293 ? 160.917 137.513 166.486 1.00 66.70  ? 293 ASN C CG  1 
ATOM 2068 O OD1 . ASN A 1 293 ? 160.979 136.359 166.907 1.00 66.70  ? 293 ASN C OD1 1 
ATOM 2069 N ND2 . ASN A 1 293 ? 159.792 138.049 166.028 1.00 66.70  ? 293 ASN C ND2 1 
ATOM 2070 N N   . GLU A 1 294 ? 163.727 136.061 166.154 1.00 79.87  ? 294 GLU C N   1 
ATOM 2071 C CA  . GLU A 1 294 ? 164.594 135.064 165.525 1.00 79.87  ? 294 GLU C CA  1 
ATOM 2072 C C   . GLU A 1 294 ? 165.298 135.632 164.300 1.00 79.87  ? 294 GLU C C   1 
ATOM 2073 O O   . GLU A 1 294 ? 165.973 134.917 163.561 1.00 79.87  ? 294 GLU C O   1 
ATOM 2074 C CB  . GLU A 1 294 ? 163.784 133.826 165.163 1.00 79.87  ? 294 GLU C CB  1 
ATOM 2075 C CG  . GLU A 1 294 ? 162.528 134.131 164.365 1.00 79.87  ? 294 GLU C CG  1 
ATOM 2076 C CD  . GLU A 1 294 ? 162.775 134.142 162.872 1.00 79.87  ? 294 GLU C CD  1 
ATOM 2077 O OE1 . GLU A 1 294 ? 163.800 133.581 162.434 1.00 79.87  ? 294 GLU C OE1 1 
ATOM 2078 O OE2 . GLU A 1 294 ? 161.947 134.718 162.135 1.00 79.87  ? 294 GLU C OE2 1 
ATOM 2079 N N   . ASP A 1 295 ? 165.156 136.938 164.075 1.00 83.92  ? 295 ASP C N   1 
ATOM 2080 C CA  . ASP A 1 295 ? 165.832 137.608 162.976 1.00 83.92  ? 295 ASP C CA  1 
ATOM 2081 C C   . ASP A 1 295 ? 167.221 138.107 163.336 1.00 83.92  ? 295 ASP C C   1 
ATOM 2082 O O   . ASP A 1 295 ? 167.929 138.589 162.446 1.00 83.92  ? 295 ASP C O   1 
ATOM 2083 C CB  . ASP A 1 295 ? 164.996 138.794 162.470 1.00 83.92  ? 295 ASP C CB  1 
ATOM 2084 C CG  . ASP A 1 295 ? 165.023 139.971 163.424 1.00 83.92  ? 295 ASP C CG  1 
ATOM 2085 O OD1 . ASP A 1 295 ? 164.576 139.813 164.580 1.00 83.92  ? 295 ASP C OD1 1 
ATOM 2086 O OD2 . ASP A 1 295 ? 165.492 141.056 163.019 1.00 83.92  ? 295 ASP C OD2 1 
ATOM 2087 N N   . VAL A 1 296 ? 167.631 138.013 164.596 1.00 83.11  ? 296 VAL C N   1 
ATOM 2088 C CA  . VAL A 1 296 ? 168.957 138.431 165.031 1.00 83.11  ? 296 VAL C CA  1 
ATOM 2089 C C   . VAL A 1 296 ? 169.756 137.181 165.371 1.00 83.11  ? 296 VAL C C   1 
ATOM 2090 O O   . VAL A 1 296 ? 169.360 136.399 166.244 1.00 83.11  ? 296 VAL C O   1 
ATOM 2091 C CB  . VAL A 1 296 ? 168.876 139.384 166.233 1.00 83.11  ? 296 VAL C CB  1 
ATOM 2092 C CG1 . VAL A 1 296 ? 170.220 139.467 166.935 1.00 83.11  ? 296 VAL C CG1 1 
ATOM 2093 C CG2 . VAL A 1 296 ? 168.414 140.760 165.783 1.00 83.11  ? 296 VAL C CG2 1 
ATOM 2094 N N   . SER A 1 297 ? 170.879 136.985 164.678 1.00 86.51  ? 297 SER C N   1 
ATOM 2095 C CA  . SER A 1 297 ? 171.696 135.800 164.890 1.00 86.51  ? 297 SER C CA  1 
ATOM 2096 C C   . SER A 1 297 ? 173.195 136.063 164.864 1.00 86.51  ? 297 SER C C   1 
ATOM 2097 O O   . SER A 1 297 ? 173.964 135.097 164.847 1.00 86.51  ? 297 SER C O   1 
ATOM 2098 C CB  . SER A 1 297 ? 171.357 134.727 163.843 1.00 86.51  ? 297 SER C CB  1 
ATOM 2099 O OG  . SER A 1 297 ? 172.085 133.535 164.083 1.00 86.51  ? 297 SER C OG  1 
ATOM 2100 N N   . ASP A 1 298 ? 173.638 137.315 164.857 1.00 82.55  ? 298 ASP C N   1 
ATOM 2101 C CA  . ASP A 1 298 ? 175.063 137.617 164.825 1.00 82.55  ? 298 ASP C CA  1 
ATOM 2102 C C   . ASP A 1 298 ? 175.293 138.974 165.480 1.00 82.55  ? 298 ASP C C   1 
ATOM 2103 O O   . ASP A 1 298 ? 174.352 139.636 165.927 1.00 82.55  ? 298 ASP C O   1 
ATOM 2104 C CB  . ASP A 1 298 ? 175.598 137.557 163.387 1.00 82.55  ? 298 ASP C CB  1 
ATOM 2105 C CG  . ASP A 1 298 ? 174.619 138.116 162.377 1.00 82.55  ? 298 ASP C CG  1 
ATOM 2106 O OD1 . ASP A 1 298 ? 173.502 138.496 162.783 1.00 82.55  ? 298 ASP C OD1 1 
ATOM 2107 O OD2 . ASP A 1 298 ? 174.965 138.174 161.178 1.00 82.55  ? 298 ASP C OD2 1 
ATOM 2108 N N   . GLU A 1 299 ? 176.563 139.383 165.539 1.00 73.19  ? 299 GLU C N   1 
ATOM 2109 C CA  . GLU A 1 299 ? 176.931 140.604 166.249 1.00 73.19  ? 299 GLU C CA  1 
ATOM 2110 C C   . GLU A 1 299 ? 176.285 141.833 165.623 1.00 73.19  ? 299 GLU C C   1 
ATOM 2111 O O   . GLU A 1 299 ? 175.749 142.692 166.332 1.00 73.19  ? 299 GLU C O   1 
ATOM 2112 C CB  . GLU A 1 299 ? 178.452 140.756 166.265 1.00 73.19  ? 299 GLU C CB  1 
ATOM 2113 C CG  . GLU A 1 299 ? 179.214 139.445 166.373 1.00 73.19  ? 299 GLU C CG  1 
ATOM 2114 C CD  . GLU A 1 299 ? 179.473 139.036 167.808 1.00 73.19  ? 299 GLU C CD  1 
ATOM 2115 O OE1 . GLU A 1 299 ? 180.359 138.186 168.035 1.00 73.19  ? 299 GLU C OE1 1 
ATOM 2116 O OE2 . GLU A 1 299 ? 178.805 139.579 168.711 1.00 73.19  ? 299 GLU C OE2 1 
ATOM 2117 N N   . LYS A 1 300 ? 176.330 141.937 164.293 1.00 71.39  ? 300 LYS C N   1 
ATOM 2118 C CA  . LYS A 1 300 ? 175.834 143.142 163.635 1.00 71.39  ? 300 LYS C CA  1 
ATOM 2119 C C   . LYS A 1 300 ? 174.327 143.294 163.786 1.00 71.39  ? 300 LYS C C   1 
ATOM 2120 O O   . LYS A 1 300 ? 173.838 144.407 164.012 1.00 71.39  ? 300 LYS C O   1 
ATOM 2121 C CB  . LYS A 1 300 ? 176.224 143.136 162.158 1.00 71.39  ? 300 LYS C CB  1 
ATOM 2122 C CG  . LYS A 1 300 ? 176.044 144.480 161.472 1.00 71.39  ? 300 LYS C CG  1 
ATOM 2123 C CD  . LYS A 1 300 ? 177.053 145.497 161.983 1.00 71.39  ? 300 LYS C CD  1 
ATOM 2124 C CE  . LYS A 1 300 ? 178.463 145.161 161.526 1.00 71.39  ? 300 LYS C CE  1 
ATOM 2125 N NZ  . LYS A 1 300 ? 179.492 145.931 162.280 1.00 71.39  ? 300 LYS C NZ  1 
ATOM 2126 N N   . THR A 1 301 ? 173.575 142.200 163.659 1.00 73.84  ? 301 THR C N   1 
ATOM 2127 C CA  . THR A 1 301 ? 172.129 142.278 163.830 1.00 73.84  ? 301 THR C CA  1 
ATOM 2128 C C   . THR A 1 301 ? 171.743 142.659 165.252 1.00 73.84  ? 301 THR C C   1 
ATOM 2129 O O   . THR A 1 301 ? 170.806 143.443 165.444 1.00 73.84  ? 301 THR C O   1 
ATOM 2130 C CB  . THR A 1 301 ? 171.473 140.949 163.457 1.00 73.84  ? 301 THR C CB  1 
ATOM 2131 O OG1 . THR A 1 301 ? 172.249 139.866 163.984 1.00 73.84  ? 301 THR C OG1 1 
ATOM 2132 C CG2 . THR A 1 301 ? 171.375 140.813 161.947 1.00 73.84  ? 301 THR C CG2 1 
ATOM 2133 N N   . ALA A 1 302 ? 172.438 142.115 166.253 1.00 69.51  ? 302 ALA C N   1 
ATOM 2134 C CA  . ALA A 1 302 ? 172.148 142.483 167.633 1.00 69.51  ? 302 ALA C CA  1 
ATOM 2135 C C   . ALA A 1 302 ? 172.414 143.959 167.885 1.00 69.51  ? 302 ALA C C   1 
ATOM 2136 O O   . ALA A 1 302 ? 171.606 144.629 168.537 1.00 69.51  ? 302 ALA C O   1 
ATOM 2137 C CB  . ALA A 1 302 ? 172.967 141.624 168.593 1.00 69.51  ? 302 ALA C CB  1 
ATOM 2138 N N   . GLU A 1 303 ? 173.528 144.485 167.372 1.00 71.73  ? 303 GLU C N   1 
ATOM 2139 C CA  . GLU A 1 303 ? 173.816 145.905 167.526 1.00 71.73  ? 303 GLU C CA  1 
ATOM 2140 C C   . GLU A 1 303 ? 172.802 146.777 166.801 1.00 71.73  ? 303 GLU C C   1 
ATOM 2141 O O   . GLU A 1 303 ? 172.522 147.889 167.258 1.00 71.73  ? 303 GLU C O   1 
ATOM 2142 C CB  . GLU A 1 303 ? 175.226 146.214 167.024 1.00 71.73  ? 303 GLU C CB  1 
ATOM 2143 C CG  . GLU A 1 303 ? 176.306 146.033 168.074 1.00 71.73  ? 303 GLU C CG  1 
ATOM 2144 C CD  . GLU A 1 303 ? 177.538 146.868 167.793 1.00 71.73  ? 303 GLU C CD  1 
ATOM 2145 O OE1 . GLU A 1 303 ? 178.660 146.362 168.000 1.00 71.73  ? 303 GLU C OE1 1 
ATOM 2146 O OE2 . GLU A 1 303 ? 177.385 148.029 167.361 1.00 71.73  ? 303 GLU C OE2 1 
ATOM 2147 N N   . ALA A 1 304 ? 172.247 146.300 165.685 1.00 66.96  ? 304 ALA C N   1 
ATOM 2148 C CA  . ALA A 1 304 ? 171.210 147.062 164.998 1.00 66.96  ? 304 ALA C CA  1 
ATOM 2149 C C   . ALA A 1 304 ? 169.968 147.206 165.865 1.00 66.96  ? 304 ALA C C   1 
ATOM 2150 O O   . ALA A 1 304 ? 169.343 148.272 165.892 1.00 66.96  ? 304 ALA C O   1 
ATOM 2151 C CB  . ALA A 1 304 ? 170.861 146.396 163.668 1.00 66.96  ? 304 ALA C CB  1 
ATOM 2152 N N   . ALA A 1 305 ? 169.594 146.142 166.580 1.00 65.83  ? 305 ALA C N   1 
ATOM 2153 C CA  . ALA A 1 305 ? 168.402 146.197 167.418 1.00 65.83  ? 305 ALA C CA  1 
ATOM 2154 C C   . ALA A 1 305 ? 168.562 147.199 168.554 1.00 65.83  ? 305 ALA C C   1 
ATOM 2155 O O   . ALA A 1 305 ? 167.654 147.995 168.819 1.00 65.83  ? 305 ALA C O   1 
ATOM 2156 C CB  . ALA A 1 305 ? 168.082 144.808 167.968 1.00 65.83  ? 305 ALA C CB  1 
ATOM 2157 N N   . MET A 1 306 ? 169.709 147.185 169.233 1.00 65.18  ? 306 MET C N   1 
ATOM 2158 C CA  . MET A 1 306 ? 169.927 148.112 170.335 1.00 65.18  ? 306 MET C CA  1 
ATOM 2159 C C   . MET A 1 306 ? 170.183 149.536 169.864 1.00 65.18  ? 306 MET C C   1 
ATOM 2160 O O   . MET A 1 306 ? 170.130 150.459 170.683 1.00 65.18  ? 306 MET C O   1 
ATOM 2161 C CB  . MET A 1 306 ? 171.087 147.632 171.207 1.00 65.18  ? 306 MET C CB  1 
ATOM 2162 C CG  . MET A 1 306 ? 171.193 146.122 171.283 1.00 65.18  ? 306 MET C CG  1 
ATOM 2163 S SD  . MET A 1 306 ? 170.228 145.407 172.624 1.00 65.18  ? 306 MET C SD  1 
ATOM 2164 C CE  . MET A 1 306 ? 171.503 145.134 173.846 1.00 65.18  ? 306 MET C CE  1 
ATOM 2165 N N   . GLN A 1 307 ? 170.459 149.737 168.574 1.00 69.00  ? 307 GLN C N   1 
ATOM 2166 C CA  . GLN A 1 307 ? 170.498 151.092 168.037 1.00 69.00  ? 307 GLN C CA  1 
ATOM 2167 C C   . GLN A 1 307 ? 169.105 151.707 168.024 1.00 69.00  ? 307 GLN C C   1 
ATOM 2168 O O   . GLN A 1 307 ? 168.951 152.919 168.215 1.00 69.00  ? 307 GLN C O   1 
ATOM 2169 C CB  . GLN A 1 307 ? 171.102 151.085 166.633 1.00 69.00  ? 307 GLN C CB  1 
ATOM 2170 C CG  . GLN A 1 307 ? 171.083 152.435 165.932 1.00 69.00  ? 307 GLN C CG  1 
ATOM 2171 C CD  . GLN A 1 307 ? 172.146 153.381 166.454 1.00 69.00  ? 307 GLN C CD  1 
ATOM 2172 O OE1 . GLN A 1 307 ? 172.039 153.904 167.563 1.00 69.00  ? 307 GLN C OE1 1 
ATOM 2173 N NE2 . GLN A 1 307 ? 173.181 153.606 165.655 1.00 69.00  ? 307 GLN C NE2 1 
ATOM 2174 N N   . ARG A 1 308 ? 168.078 150.881 167.809 1.00 61.58  ? 308 ARG C N   1 
ATOM 2175 C CA  . ARG A 1 308 ? 166.706 151.370 167.875 1.00 61.58  ? 308 ARG C CA  1 
ATOM 2176 C C   . ARG A 1 308 ? 166.371 151.872 169.273 1.00 61.58  ? 308 ARG C C   1 
ATOM 2177 O O   . ARG A 1 308 ? 165.665 152.875 169.429 1.00 61.58  ? 308 ARG C O   1 
ATOM 2178 C CB  . ARG A 1 308 ? 165.738 150.267 167.449 1.00 61.58  ? 308 ARG C CB  1 
ATOM 2179 C CG  . ARG A 1 308 ? 165.849 149.885 165.983 1.00 61.58  ? 308 ARG C CG  1 
ATOM 2180 C CD  . ARG A 1 308 ? 165.388 148.459 165.741 1.00 61.58  ? 308 ARG C CD  1 
ATOM 2181 N NE  . ARG A 1 308 ? 164.113 148.172 166.386 1.00 61.58  ? 308 ARG C NE  1 
ATOM 2182 C CZ  . ARG A 1 308 ? 163.538 146.978 166.406 1.00 61.58  ? 308 ARG C CZ  1 
ATOM 2183 N NH1 . ARG A 1 308 ? 164.103 145.930 165.830 1.00 61.58  ? 308 ARG C NH1 1 
ATOM 2184 N NH2 . ARG A 1 308 ? 162.369 146.831 167.021 1.00 61.58  ? 308 ARG C NH2 1 
ATOM 2185 N N   . LEU A 1 309 ? 166.867 151.183 170.303 1.00 54.31  ? 309 LEU C N   1 
ATOM 2186 C CA  . LEU A 1 309 ? 166.650 151.636 171.674 1.00 54.31  ? 309 LEU C CA  1 
ATOM 2187 C C   . LEU A 1 309 ? 167.277 153.002 171.913 1.00 54.31  ? 309 LEU C C   1 
ATOM 2188 O O   . LEU A 1 309 ? 166.690 153.851 172.593 1.00 54.31  ? 309 LEU C O   1 
ATOM 2189 C CB  . LEU A 1 309 ? 167.208 150.608 172.656 1.00 54.31  ? 309 LEU C CB  1 
ATOM 2190 C CG  . LEU A 1 309 ? 166.641 150.629 174.074 1.00 54.31  ? 309 LEU C CG  1 
ATOM 2191 C CD1 . LEU A 1 309 ? 165.161 150.351 174.066 1.00 54.31  ? 309 LEU C CD1 1 
ATOM 2192 C CD2 . LEU A 1 309 ? 167.362 149.608 174.933 1.00 54.31  ? 309 LEU C CD2 1 
ATOM 2193 N N   . LYS A 1 310 ? 168.471 153.233 171.365 1.00 58.90  ? 310 LYS C N   1 
ATOM 2194 C CA  . LYS A 1 310 ? 169.123 154.526 171.525 1.00 58.90  ? 310 LYS C CA  1 
ATOM 2195 C C   . LYS A 1 310 ? 168.332 155.656 170.879 1.00 58.90  ? 310 LYS C C   1 
ATOM 2196 O O   . LYS A 1 310 ? 168.394 156.793 171.359 1.00 58.90  ? 310 LYS C O   1 
ATOM 2197 C CB  . LYS A 1 310 ? 170.534 154.475 170.938 1.00 58.90  ? 310 LYS C CB  1 
ATOM 2198 C CG  . LYS A 1 310 ? 171.391 155.684 171.261 1.00 58.90  ? 310 LYS C CG  1 
ATOM 2199 C CD  . LYS A 1 310 ? 172.233 155.444 172.501 1.00 58.90  ? 310 LYS C CD  1 
ATOM 2200 C CE  . LYS A 1 310 ? 172.848 156.736 173.010 1.00 58.90  ? 310 LYS C CE  1 
ATOM 2201 N NZ  . LYS A 1 310 ? 173.545 156.543 174.311 1.00 58.90  ? 310 LYS C NZ  1 
ATOM 2202 N N   . ALA A 1 311 ? 167.582 155.369 169.812 1.00 58.91  ? 311 ALA C N   1 
ATOM 2203 C CA  . ALA A 1 311 ? 166.821 156.409 169.130 1.00 58.91  ? 311 ALA C CA  1 
ATOM 2204 C C   . ALA A 1 311 ? 165.624 156.883 169.941 1.00 58.91  ? 311 ALA C C   1 
ATOM 2205 O O   . ALA A 1 311 ? 165.051 157.930 169.619 1.00 58.91  ? 311 ALA C O   1 
ATOM 2206 C CB  . ALA A 1 311 ? 166.355 155.910 167.763 1.00 58.91  ? 311 ALA C CB  1 
ATOM 2207 N N   . ALA A 1 312 ? 165.234 156.148 170.979 1.00 56.65  ? 312 ALA C N   1 
ATOM 2208 C CA  . ALA A 1 312 ? 164.111 156.541 171.820 1.00 56.65  ? 312 ALA C CA  1 
ATOM 2209 C C   . ALA A 1 312 ? 164.414 157.758 172.683 1.00 56.65  ? 312 ALA C C   1 
ATOM 2210 O O   . ALA A 1 312 ? 163.492 158.298 173.303 1.00 56.65  ? 312 ALA C O   1 
ATOM 2211 C CB  . ALA A 1 312 ? 163.686 155.372 172.710 1.00 56.65  ? 312 ALA C CB  1 
ATOM 2212 N N   . ASN A 1 313 ? 165.670 158.193 172.736 1.00 58.15  ? 313 ASN C N   1 
ATOM 2213 C CA  . ASN A 1 313 ? 166.087 159.359 173.512 1.00 58.15  ? 313 ASN C CA  1 
ATOM 2214 C C   . ASN A 1 313 ? 165.722 159.204 174.986 1.00 58.15  ? 313 ASN C C   1 
ATOM 2215 O O   . ASN A 1 313 ? 165.261 160.138 175.646 1.00 58.15  ? 313 ASN C O   1 
ATOM 2216 C CB  . ASN A 1 313 ? 165.499 160.641 172.931 1.00 58.15  ? 313 ASN C CB  1 
ATOM 2217 C CG  . ASN A 1 313 ? 166.364 161.232 171.839 1.00 58.15  ? 313 ASN C CG  1 
ATOM 2218 O OD1 . ASN A 1 313 ? 167.444 160.721 171.546 1.00 58.15  ? 313 ASN C OD1 1 
ATOM 2219 N ND2 . ASN A 1 313 ? 165.895 162.314 171.230 1.00 58.15  ? 313 ASN C ND2 1 
ATOM 2220 N N   . ILE A 1 314 ? 165.932 157.998 175.502 1.00 46.75  ? 314 ILE C N   1 
ATOM 2221 C CA  . ILE A 1 314 ? 165.795 157.735 176.931 1.00 46.75  ? 314 ILE C CA  1 
ATOM 2222 C C   . ILE A 1 314 ? 167.042 158.276 177.619 1.00 46.75  ? 314 ILE C C   1 
ATOM 2223 O O   . ILE A 1 314 ? 168.163 157.967 177.188 1.00 46.75  ? 314 ILE C O   1 
ATOM 2224 C CB  . ILE A 1 314 ? 165.598 156.239 177.214 1.00 46.75  ? 314 ILE C CB  1 
ATOM 2225 C CG1 . ILE A 1 314 ? 164.175 155.814 176.854 1.00 46.75  ? 314 ILE C CG1 1 
ATOM 2226 C CG2 . ILE A 1 314 ? 165.892 155.930 178.672 1.00 46.75  ? 314 ILE C CG2 1 
ATOM 2227 C CD1 . ILE A 1 314 ? 163.131 156.313 177.821 1.00 46.75  ? 314 ILE C CD1 1 
ATOM 2228 N N   . PRO A 1 315 ? 166.905 159.086 178.674 1.00 53.89  ? 315 PRO C N   1 
ATOM 2229 C CA  . PRO A 1 315 ? 168.089 159.676 179.314 1.00 53.89  ? 315 PRO C CA  1 
ATOM 2230 C C   . PRO A 1 315 ? 169.037 158.630 179.878 1.00 53.89  ? 315 PRO C C   1 
ATOM 2231 O O   . PRO A 1 315 ? 168.664 157.464 180.036 1.00 53.89  ? 315 PRO C O   1 
ATOM 2232 C CB  . PRO A 1 315 ? 167.490 160.554 180.422 1.00 53.89  ? 315 PRO C CB  1 
ATOM 2233 C CG  . PRO A 1 315 ? 166.066 160.766 180.016 1.00 53.89  ? 315 PRO C CG  1 
ATOM 2234 C CD  . PRO A 1 315 ? 165.661 159.501 179.337 1.00 53.89  ? 315 PRO C CD  1 
ATOM 2235 N N   . GLU A 1 316 ? 170.271 159.036 180.170 1.00 58.03  ? 316 GLU C N   1 
ATOM 2236 C CA  . GLU A 1 316 ? 171.307 158.099 180.584 1.00 58.03  ? 316 GLU C CA  1 
ATOM 2237 C C   . GLU A 1 316 ? 171.284 157.844 182.086 1.00 58.03  ? 316 GLU C C   1 
ATOM 2238 O O   . GLU A 1 316 ? 171.238 156.691 182.525 1.00 58.03  ? 316 GLU C O   1 
ATOM 2239 C CB  . GLU A 1 316 ? 172.685 158.621 180.164 1.00 58.03  ? 316 GLU C CB  1 
ATOM 2240 C CG  . GLU A 1 316 ? 172.916 158.727 178.654 1.00 58.03  ? 316 GLU C CG  1 
ATOM 2241 C CD  . GLU A 1 316 ? 172.627 157.447 177.881 1.00 58.03  ? 316 GLU C CD  1 
ATOM 2242 O OE1 . GLU A 1 316 ? 172.492 157.529 176.642 1.00 58.03  ? 316 GLU C OE1 1 
ATOM 2243 O OE2 . GLU A 1 316 ? 172.572 156.357 178.488 1.00 58.03  ? 316 GLU C OE2 1 
ATOM 2244 N N   . HIS A 1 317 ? 171.330 158.912 182.881 1.00 66.30  ? 317 HIS C N   1 
ATOM 2245 C CA  . HIS A 1 317 ? 171.469 158.793 184.328 1.00 66.30  ? 317 HIS C CA  1 
ATOM 2246 C C   . HIS A 1 317 ? 170.205 158.249 184.980 1.00 66.30  ? 317 HIS C C   1 
ATOM 2247 O O   . HIS A 1 317 ? 169.099 158.452 184.472 1.00 66.30  ? 317 HIS C O   1 
ATOM 2248 C CB  . HIS A 1 317 ? 171.822 160.148 184.947 1.00 66.30  ? 317 HIS C CB  1 
ATOM 2249 C CG  . HIS A 1 317 ? 171.038 161.294 184.388 1.00 66.30  ? 317 HIS C CG  1 
ATOM 2250 N ND1 . HIS A 1 317 ? 171.208 161.759 183.101 1.00 66.30  ? 317 HIS C ND1 1 
ATOM 2251 C CD2 . HIS A 1 317 ? 170.074 162.067 184.942 1.00 66.30  ? 317 HIS C CD2 1 
ATOM 2252 C CE1 . HIS A 1 317 ? 170.385 162.770 182.888 1.00 66.30  ? 317 HIS C CE1 1 
ATOM 2253 N NE2 . HIS A 1 317 ? 169.685 162.976 183.989 1.00 66.30  ? 317 HIS C NE2 1 
ATOM 2254 N N   . ASN A 1 318 ? 170.369 157.565 186.114 1.00 58.31  ? 318 ASN C N   1 
ATOM 2255 C CA  . ASN A 1 318 ? 169.262 157.063 186.931 1.00 58.31  ? 318 ASN C CA  1 
ATOM 2256 C C   . ASN A 1 318 ? 168.376 156.079 186.176 1.00 58.31  ? 318 ASN C C   1 
ATOM 2257 O O   . ASN A 1 318 ? 167.170 156.007 186.425 1.00 58.31  ? 318 ASN C O   1 
ATOM 2258 C CB  . ASN A 1 318 ? 168.414 158.212 187.488 1.00 58.31  ? 318 ASN C CB  1 
ATOM 2259 C CG  . ASN A 1 318 ? 169.020 158.835 188.727 1.00 58.31  ? 318 ASN C CG  1 
ATOM 2260 O OD1 . ASN A 1 318 ? 169.771 159.807 188.643 1.00 58.31  ? 318 ASN C OD1 1 
ATOM 2261 N ND2 . ASN A 1 318 ? 168.694 158.280 189.887 1.00 58.31  ? 318 ASN C ND2 1 
ATOM 2262 N N   . THR A 1 319 ? 168.946 155.313 185.252 1.00 47.83  ? 319 THR C N   1 
ATOM 2263 C CA  . THR A 1 319 ? 168.210 154.270 184.553 1.00 47.83  ? 319 THR C CA  1 
ATOM 2264 C C   . THR A 1 319 ? 168.840 152.915 184.830 1.00 47.83  ? 319 THR C C   1 
ATOM 2265 O O   . THR A 1 319 ? 170.060 152.803 184.974 1.00 47.83  ? 319 THR C O   1 
ATOM 2266 C CB  . THR A 1 319 ? 168.179 154.514 183.045 1.00 47.83  ? 319 THR C CB  1 
ATOM 2267 O OG1 . THR A 1 319 ? 169.334 153.921 182.441 1.00 47.83  ? 319 THR C OG1 1 
ATOM 2268 C CG2 . THR A 1 319 ? 168.162 155.991 182.748 1.00 47.83  ? 319 THR C CG2 1 
ATOM 2269 N N   . ILE A 1 320 ? 168.000 151.889 184.906 1.00 35.96  ? 320 ILE C N   1 
ATOM 2270 C CA  . ILE A 1 320 ? 168.457 150.518 185.079 1.00 35.96  ? 320 ILE C CA  1 
ATOM 2271 C C   . ILE A 1 320 ? 167.888 149.700 183.929 1.00 35.96  ? 320 ILE C C   1 
ATOM 2272 O O   . ILE A 1 320 ? 166.752 149.931 183.501 1.00 35.96  ? 320 ILE C O   1 
ATOM 2273 C CB  . ILE A 1 320 ? 168.051 149.934 186.445 1.00 35.96  ? 320 ILE C CB  1 
ATOM 2274 C CG1 . ILE A 1 320 ? 169.027 148.838 186.870 1.00 35.96  ? 320 ILE C CG1 1 
ATOM 2275 C CG2 . ILE A 1 320 ? 166.621 149.424 186.443 1.00 35.96  ? 320 ILE C CG2 1 
ATOM 2276 C CD1 . ILE A 1 320 ? 168.951 148.504 188.338 1.00 35.96  ? 320 ILE C CD1 1 
ATOM 2277 N N   . GLY A 1 321 ? 168.691 148.792 183.389 1.00 38.28  ? 321 GLY C N   1 
ATOM 2278 C CA  . GLY A 1 321 ? 168.296 147.999 182.244 1.00 38.28  ? 321 GLY C CA  1 
ATOM 2279 C C   . GLY A 1 321 ? 167.966 146.578 182.653 1.00 38.28  ? 321 GLY C C   1 
ATOM 2280 O O   . GLY A 1 321 ? 168.482 146.067 183.648 1.00 38.28  ? 321 GLY C O   1 
ATOM 2281 N N   . PHE A 1 322 ? 167.095 145.946 181.879 1.00 28.77  ? 322 PHE C N   1 
ATOM 2282 C CA  . PHE A 1 322 ? 166.714 144.564 182.106 1.00 28.77  ? 322 PHE C CA  1 
ATOM 2283 C C   . PHE A 1 322 ? 166.822 143.772 180.811 1.00 28.77  ? 322 PHE C C   1 
ATOM 2284 O O   . PHE A 1 322 ? 166.620 144.300 179.715 1.00 28.77  ? 322 PHE C O   1 
ATOM 2285 C CB  . PHE A 1 322 ? 165.294 144.462 182.672 1.00 28.77  ? 322 PHE C CB  1 
ATOM 2286 C CG  . PHE A 1 322 ? 165.165 144.962 184.082 1.00 28.77  ? 322 PHE C CG  1 
ATOM 2287 C CD1 . PHE A 1 322 ? 165.514 144.155 185.149 1.00 28.77  ? 322 PHE C CD1 1 
ATOM 2288 C CD2 . PHE A 1 322 ? 164.695 146.235 184.341 1.00 28.77  ? 322 PHE C CD2 1 
ATOM 2289 C CE1 . PHE A 1 322 ? 165.397 144.608 186.446 1.00 28.77  ? 322 PHE C CE1 1 
ATOM 2290 C CE2 . PHE A 1 322 ? 164.576 146.692 185.637 1.00 28.77  ? 322 PHE C CE2 1 
ATOM 2291 C CZ  . PHE A 1 322 ? 164.928 145.878 186.690 1.00 28.77  ? 322 PHE C CZ  1 
ATOM 2292 N N   . MET A 1 323 ? 167.147 142.490 180.952 1.00 47.17  ? 323 MET C N   1 
ATOM 2293 C CA  . MET A 1 323 ? 167.281 141.588 179.813 1.00 47.17  ? 323 MET C CA  1 
ATOM 2294 C C   . MET A 1 323 ? 166.725 140.231 180.213 1.00 47.17  ? 323 MET C C   1 
ATOM 2295 O O   . MET A 1 323 ? 167.367 139.493 180.965 1.00 47.17  ? 323 MET C O   1 
ATOM 2296 C CB  . MET A 1 323 ? 168.737 141.464 179.368 1.00 47.17  ? 323 MET C CB  1 
ATOM 2297 C CG  . MET A 1 323 ? 168.952 140.432 178.278 1.00 47.17  ? 323 MET C CG  1 
ATOM 2298 S SD  . MET A 1 323 ? 170.492 139.517 178.460 1.00 47.17  ? 323 MET C SD  1 
ATOM 2299 C CE  . MET A 1 323 ? 171.684 140.833 178.249 1.00 47.17  ? 323 MET C CE  1 
ATOM 2300 N N   . PHE A 1 324 ? 165.537 139.905 179.718 1.00 44.02  ? 324 PHE C N   1 
ATOM 2301 C CA  . PHE A 1 324 ? 164.921 138.604 179.935 1.00 44.02  ? 324 PHE C CA  1 
ATOM 2302 C C   . PHE A 1 324 ? 165.004 137.795 178.650 1.00 44.02  ? 324 PHE C C   1 
ATOM 2303 O O   . PHE A 1 324 ? 164.490 138.221 177.611 1.00 44.02  ? 324 PHE C O   1 
ATOM 2304 C CB  . PHE A 1 324 ? 163.469 138.758 180.385 1.00 44.02  ? 324 PHE C CB  1 
ATOM 2305 C CG  . PHE A 1 324 ? 163.246 139.910 181.319 1.00 44.02  ? 324 PHE C CG  1 
ATOM 2306 C CD1 . PHE A 1 324 ? 163.770 139.891 182.598 1.00 44.02  ? 324 PHE C CD1 1 
ATOM 2307 C CD2 . PHE A 1 324 ? 162.516 141.012 180.921 1.00 44.02  ? 324 PHE C CD2 1 
ATOM 2308 C CE1 . PHE A 1 324 ? 163.567 140.943 183.463 1.00 44.02  ? 324 PHE C CE1 1 
ATOM 2309 C CE2 . PHE A 1 324 ? 162.315 142.068 181.781 1.00 44.02  ? 324 PHE C CE2 1 
ATOM 2310 C CZ  . PHE A 1 324 ? 162.839 142.033 183.054 1.00 44.02  ? 324 PHE C CZ  1 
ATOM 2311 N N   . ALA A 1 325 ? 165.647 136.632 178.724 1.00 47.37  ? 325 ALA C N   1 
ATOM 2312 C CA  . ALA A 1 325 ? 165.885 135.826 177.535 1.00 47.37  ? 325 ALA C CA  1 
ATOM 2313 C C   . ALA A 1 325 ? 165.451 134.383 177.747 1.00 47.37  ? 325 ALA C C   1 
ATOM 2314 O O   . ALA A 1 325 ? 164.902 134.041 178.799 1.00 47.37  ? 325 ALA C O   1 
ATOM 2315 C CB  . ALA A 1 325 ? 167.361 135.881 177.143 1.00 47.37  ? 325 ALA C CB  1 
ATOM 2316 N N   . CYS A 1 326 ? 165.691 133.533 176.756 1.00 56.73  ? 326 CYS C N   1 
ATOM 2317 C CA  . CYS A 1 326 ? 165.330 132.127 176.816 1.00 56.73  ? 326 CYS C CA  1 
ATOM 2318 C C   . CYS A 1 326 ? 166.573 131.274 177.019 1.00 56.73  ? 326 CYS C C   1 
ATOM 2319 O O   . CYS A 1 326 ? 167.670 131.618 176.571 1.00 56.73  ? 326 CYS C O   1 
ATOM 2320 C CB  . CYS A 1 326 ? 164.604 131.689 175.541 1.00 56.73  ? 326 CYS C CB  1 
ATOM 2321 S SG  . CYS A 1 326 ? 163.593 130.204 175.732 1.00 56.73  ? 326 CYS C SG  1 
ATOM 2322 N N   . VAL A 1 327 ? 166.384 130.143 177.703 1.00 57.22  ? 327 VAL C N   1 
ATOM 2323 C CA  . VAL A 1 327 ? 167.492 129.227 177.939 1.00 57.22  ? 327 VAL C CA  1 
ATOM 2324 C C   . VAL A 1 327 ? 168.035 128.664 176.632 1.00 57.22  ? 327 VAL C C   1 
ATOM 2325 O O   . VAL A 1 327 ? 169.159 128.151 176.601 1.00 57.22  ? 327 VAL C O   1 
ATOM 2326 C CB  . VAL A 1 327 ? 167.059 128.098 178.894 1.00 57.22  ? 327 VAL C CB  1 
ATOM 2327 C CG1 . VAL A 1 327 ? 166.363 126.982 178.131 1.00 57.22  ? 327 VAL C CG1 1 
ATOM 2328 C CG2 . VAL A 1 327 ? 168.255 127.563 179.664 1.00 57.22  ? 327 VAL C CG2 1 
ATOM 2329 N N   . GLY A 1 328 ? 167.266 128.751 175.547 1.00 61.84  ? 328 GLY C N   1 
ATOM 2330 C CA  . GLY A 1 328 ? 167.744 128.344 174.240 1.00 61.84  ? 328 GLY C CA  1 
ATOM 2331 C C   . GLY A 1 328 ? 168.585 129.383 173.530 1.00 61.84  ? 328 GLY C C   1 
ATOM 2332 O O   . GLY A 1 328 ? 169.062 129.114 172.423 1.00 61.84  ? 328 GLY C O   1 
ATOM 2333 N N   . ARG A 1 329 ? 168.771 130.553 174.131 1.00 67.84  ? 329 ARG C N   1 
ATOM 2334 C CA  . ARG A 1 329 ? 169.606 131.603 173.572 1.00 67.84  ? 329 ARG C CA  1 
ATOM 2335 C C   . ARG A 1 329 ? 170.850 131.801 174.428 1.00 67.84  ? 329 ARG C C   1 
ATOM 2336 O O   . ARG A 1 329 ? 170.805 131.699 175.656 1.00 67.84  ? 329 ARG C O   1 
ATOM 2337 C CB  . ARG A 1 329 ? 168.836 132.919 173.464 1.00 67.84  ? 329 ARG C CB  1 
ATOM 2338 C CG  . ARG A 1 329 ? 169.633 134.041 172.825 1.00 67.84  ? 329 ARG C CG  1 
ATOM 2339 C CD  . ARG A 1 329 ? 168.735 135.158 172.341 1.00 67.84  ? 329 ARG C CD  1 
ATOM 2340 N NE  . ARG A 1 329 ? 167.538 134.644 171.692 1.00 67.84  ? 329 ARG C NE  1 
ATOM 2341 C CZ  . ARG A 1 329 ? 167.220 134.873 170.426 1.00 67.84  ? 329 ARG C CZ  1 
ATOM 2342 N NH1 . ARG A 1 329 ? 167.997 135.601 169.641 1.00 67.84  ? 329 ARG C NH1 1 
ATOM 2343 N NH2 . ARG A 1 329 ? 166.098 134.356 169.934 1.00 67.84  ? 329 ARG C NH2 1 
ATOM 2344 N N   . GLY A 1 330 ? 171.967 132.080 173.763 1.00 84.25  ? 330 GLY C N   1 
ATOM 2345 C CA  . GLY A 1 330 ? 173.220 132.277 174.458 1.00 84.25  ? 330 GLY C CA  1 
ATOM 2346 C C   . GLY A 1 330 ? 174.386 131.623 173.751 1.00 84.25  ? 330 GLY C C   1 
ATOM 2347 O O   . GLY A 1 330 ? 174.679 131.937 172.593 1.00 84.25  ? 330 GLY C O   1 
ATOM 2348 N N   . PHE A 1 331 ? 175.065 130.713 174.451 1.00 92.91  ? 331 PHE C N   1 
ATOM 2349 C CA  . PHE A 1 331 ? 176.192 130.003 173.856 1.00 92.91  ? 331 PHE C CA  1 
ATOM 2350 C C   . PHE A 1 331 ? 175.742 129.194 172.645 1.00 92.91  ? 331 PHE C C   1 
ATOM 2351 O O   . PHE A 1 331 ? 176.407 129.196 171.603 1.00 92.91  ? 331 PHE C O   1 
ATOM 2352 C CB  . PHE A 1 331 ? 176.831 129.098 174.913 1.00 92.91  ? 331 PHE C CB  1 
ATOM 2353 C CG  . PHE A 1 331 ? 178.190 128.562 174.543 1.00 92.91  ? 331 PHE C CG  1 
ATOM 2354 C CD1 . PHE A 1 331 ? 178.826 128.943 173.373 1.00 92.91  ? 331 PHE C CD1 1 
ATOM 2355 C CD2 . PHE A 1 331 ? 178.855 127.706 175.406 1.00 92.91  ? 331 PHE C CD2 1 
ATOM 2356 C CE1 . PHE A 1 331 ? 180.078 128.451 173.056 1.00 92.91  ? 331 PHE C CE1 1 
ATOM 2357 C CE2 . PHE A 1 331 ? 180.105 127.211 175.093 1.00 92.91  ? 331 PHE C CE2 1 
ATOM 2358 C CZ  . PHE A 1 331 ? 180.718 127.585 173.917 1.00 92.91  ? 331 PHE C CZ  1 
ATOM 2359 N N   . GLN A 1 332 ? 174.601 128.512 172.758 1.00 90.40  ? 332 GLN C N   1 
ATOM 2360 C CA  . GLN A 1 332 ? 174.159 127.619 171.692 1.00 90.40  ? 332 GLN C CA  1 
ATOM 2361 C C   . GLN A 1 332 ? 173.656 128.388 170.474 1.00 90.40  ? 332 GLN C C   1 
ATOM 2362 O O   . GLN A 1 332 ? 174.014 128.068 169.334 1.00 90.40  ? 332 GLN C O   1 
ATOM 2363 C CB  . GLN A 1 332 ? 173.071 126.680 172.217 1.00 90.40  ? 332 GLN C CB  1 
ATOM 2364 C CG  . GLN A 1 332 ? 173.087 125.290 171.598 1.00 90.40  ? 332 GLN C CG  1 
ATOM 2365 C CD  . GLN A 1 332 ? 174.372 124.531 171.875 1.00 90.40  ? 332 GLN C CD  1 
ATOM 2366 O OE1 . GLN A 1 332 ? 175.083 124.818 172.839 1.00 90.40  ? 332 GLN C OE1 1 
ATOM 2367 N NE2 . GLN A 1 332 ? 174.677 123.557 171.027 1.00 90.40  ? 332 GLN C NE2 1 
ATOM 2368 N N   . TYR A 1 333 ? 172.827 129.409 170.692 1.00 82.90  ? 333 TYR C N   1 
ATOM 2369 C CA  . TYR A 1 333 ? 172.092 130.008 169.583 1.00 82.90  ? 333 TYR C CA  1 
ATOM 2370 C C   . TYR A 1 333 ? 173.009 130.839 168.694 1.00 82.90  ? 333 TYR C C   1 
ATOM 2371 O O   . TYR A 1 333 ? 173.188 130.514 167.516 1.00 82.90  ? 333 TYR C O   1 
ATOM 2372 C CB  . TYR A 1 333 ? 170.930 130.856 170.105 1.00 82.90  ? 333 TYR C CB  1 
ATOM 2373 C CG  . TYR A 1 333 ? 169.929 131.238 169.038 1.00 82.90  ? 333 TYR C CG  1 
ATOM 2374 C CD1 . TYR A 1 333 ? 169.390 130.279 168.193 1.00 82.90  ? 333 TYR C CD1 1 
ATOM 2375 C CD2 . TYR A 1 333 ? 169.521 132.552 168.878 1.00 82.90  ? 333 TYR C CD2 1 
ATOM 2376 C CE1 . TYR A 1 333 ? 168.475 130.620 167.217 1.00 82.90  ? 333 TYR C CE1 1 
ATOM 2377 C CE2 . TYR A 1 333 ? 168.606 132.903 167.905 1.00 82.90  ? 333 TYR C CE2 1 
ATOM 2378 C CZ  . TYR A 1 333 ? 168.087 131.934 167.077 1.00 82.90  ? 333 TYR C CZ  1 
ATOM 2379 O OH  . TYR A 1 333 ? 167.174 132.277 166.106 1.00 82.90  ? 333 TYR C OH  1 
ATOM 2380 N N   . TYR A 1 334 ? 173.598 131.904 169.234 1.00 87.92  ? 334 TYR C N   1 
ATOM 2381 C CA  . TYR A 1 334 ? 174.647 132.603 168.501 1.00 87.92  ? 334 TYR C CA  1 
ATOM 2382 C C   . TYR A 1 334 ? 175.932 131.789 168.554 1.00 87.92  ? 334 TYR C C   1 
ATOM 2383 O O   . TYR A 1 334 ? 176.339 131.321 169.622 1.00 87.92  ? 334 TYR C O   1 
ATOM 2384 C CB  . TYR A 1 334 ? 174.869 134.027 169.028 1.00 87.92  ? 334 TYR C CB  1 
ATOM 2385 C CG  . TYR A 1 334 ? 173.615 134.830 169.328 1.00 87.92  ? 334 TYR C CG  1 
ATOM 2386 C CD1 . TYR A 1 334 ? 172.404 134.541 168.711 1.00 87.92  ? 334 TYR C CD1 1 
ATOM 2387 C CD2 . TYR A 1 334 ? 173.667 135.939 170.154 1.00 87.92  ? 334 TYR C CD2 1 
ATOM 2388 C CE1 . TYR A 1 334 ? 171.273 135.294 168.966 1.00 87.92  ? 334 TYR C CE1 1 
ATOM 2389 C CE2 . TYR A 1 334 ? 172.541 136.696 170.419 1.00 87.92  ? 334 TYR C CE2 1 
ATOM 2390 C CZ  . TYR A 1 334 ? 171.346 136.370 169.819 1.00 87.92  ? 334 TYR C CZ  1 
ATOM 2391 O OH  . TYR A 1 334 ? 170.219 137.118 170.069 1.00 87.92  ? 334 TYR C OH  1 
ATOM 2392 N N   . ARG A 1 335 ? 176.567 131.613 167.396 1.00 94.71  ? 335 ARG C N   1 
ATOM 2393 C CA  . ARG A 1 335 ? 177.617 130.619 167.218 1.00 94.71  ? 335 ARG C CA  1 
ATOM 2394 C C   . ARG A 1 335 ? 178.818 130.838 168.131 1.00 94.71  ? 335 ARG C C   1 
ATOM 2395 O O   . ARG A 1 335 ? 179.597 131.773 167.926 1.00 94.71  ? 335 ARG C O   1 
ATOM 2396 C CB  . ARG A 1 335 ? 178.078 130.613 165.759 1.00 94.71  ? 335 ARG C CB  1 
ATOM 2397 C CG  . ARG A 1 335 ? 177.028 130.149 164.756 1.00 94.71  ? 335 ARG C CG  1 
ATOM 2398 C CD  . ARG A 1 335 ? 176.469 128.726 164.938 1.00 94.71  ? 335 ARG C CD  1 
ATOM 2399 N NE  . ARG A 1 335 ? 177.483 127.686 165.097 1.00 94.71  ? 335 ARG C NE  1 
ATOM 2400 C CZ  . ARG A 1 335 ? 177.987 127.256 166.247 1.00 94.71  ? 335 ARG C CZ  1 
ATOM 2401 N NH1 . ARG A 1 335 ? 177.478 127.623 167.410 1.00 94.71  ? 335 ARG C NH1 1 
ATOM 2402 N NH2 . ARG A 1 335 ? 178.994 126.388 166.226 1.00 94.71  ? 335 ARG C NH2 1 
ATOM 2403 N N   . ALA A 1 336 ? 178.977 129.965 169.127 1.00 96.49  ? 336 ALA C N   1 
ATOM 2404 C CA  . ALA A 1 336 ? 180.199 129.848 169.918 1.00 96.49  ? 336 ALA C CA  1 
ATOM 2405 C C   . ALA A 1 336 ? 180.636 131.132 170.618 1.00 96.49  ? 336 ALA C C   1 
ATOM 2406 O O   . ALA A 1 336 ? 181.817 131.279 170.949 1.00 96.49  ? 336 ALA C O   1 
ATOM 2407 C CB  . ALA A 1 336 ? 181.341 129.342 169.033 1.00 96.49  ? 336 ALA C CB  1 
ATOM 2408 N N   . LYS A 1 337 ? 179.714 132.056 170.864 1.00 91.85  ? 337 LYS C N   1 
ATOM 2409 C CA  . LYS A 1 337 ? 180.025 133.276 171.596 1.00 91.85  ? 337 LYS C CA  1 
ATOM 2410 C C   . LYS A 1 337 ? 179.113 133.436 172.809 1.00 91.85  ? 337 LYS C C   1 
ATOM 2411 O O   . LYS A 1 337 ? 178.055 132.811 172.917 1.00 91.85  ? 337 LYS C O   1 
ATOM 2412 C CB  . LYS A 1 337 ? 179.912 134.509 170.692 1.00 91.85  ? 337 LYS C CB  1 
ATOM 2413 C CG  . LYS A 1 337 ? 180.476 134.343 169.294 1.00 91.85  ? 337 LYS C CG  1 
ATOM 2414 C CD  . LYS A 1 337 ? 181.957 134.014 169.329 1.00 91.85  ? 337 LYS C CD  1 
ATOM 2415 C CE  . LYS A 1 337 ? 182.586 134.171 167.956 1.00 91.85  ? 337 LYS C CE  1 
ATOM 2416 N NZ  . LYS A 1 337 ? 181.737 133.561 166.897 1.00 91.85  ? 337 LYS C NZ  1 
ATOM 2417 N N   . GLY A 1 338 ? 179.546 134.295 173.730 1.00 79.18  ? 338 GLY C N   1 
ATOM 2418 C CA  . GLY A 1 338 ? 178.759 134.647 174.896 1.00 79.18  ? 338 GLY C CA  1 
ATOM 2419 C C   . GLY A 1 338 ? 178.953 136.101 175.273 1.00 79.18  ? 338 GLY C C   1 
ATOM 2420 O O   . GLY A 1 338 ? 179.837 136.764 174.724 1.00 79.18  ? 338 GLY C O   1 
ATOM 2421 N N   . ASN A 1 339 ? 178.144 136.606 176.208 1.00 74.10  ? 339 ASN C N   1 
ATOM 2422 C CA  . ASN A 1 339 ? 178.174 138.014 176.596 1.00 74.10  ? 339 ASN C CA  1 
ATOM 2423 C C   . ASN A 1 339 ? 178.060 138.914 175.375 1.00 74.10  ? 339 ASN C C   1 
ATOM 2424 O O   . ASN A 1 339 ? 178.744 139.937 175.279 1.00 74.10  ? 339 ASN C O   1 
ATOM 2425 C CB  . ASN A 1 339 ? 179.444 138.337 177.388 1.00 74.10  ? 339 ASN C CB  1 
ATOM 2426 C CG  . ASN A 1 339 ? 179.147 138.998 178.721 1.00 74.10  ? 339 ASN C CG  1 
ATOM 2427 O OD1 . ASN A 1 339 ? 178.020 138.958 179.212 1.00 74.10  ? 339 ASN C OD1 1 
ATOM 2428 N ND2 . ASN A 1 339 ? 180.168 139.602 179.319 1.00 74.10  ? 339 ASN C ND2 1 
ATOM 2429 N N   . VAL A 1 340 ? 177.192 138.535 174.441 1.00 76.92  ? 340 VAL C N   1 
ATOM 2430 C CA  . VAL A 1 340 ? 177.031 139.244 173.178 1.00 76.92  ? 340 VAL C CA  1 
ATOM 2431 C C   . VAL A 1 340 ? 175.935 140.301 173.273 1.00 76.92  ? 340 VAL C C   1 
ATOM 2432 O O   . VAL A 1 340 ? 176.113 141.429 172.800 1.00 76.92  ? 340 VAL C O   1 
ATOM 2433 C CB  . VAL A 1 340 ? 176.770 138.242 172.039 1.00 76.92  ? 340 VAL C CB  1 
ATOM 2434 C CG1 . VAL A 1 340 ? 175.604 137.362 172.383 1.00 76.92  ? 340 VAL C CG1 1 
ATOM 2435 C CG2 . VAL A 1 340 ? 176.483 138.982 170.751 1.00 76.92  ? 340 VAL C CG2 1 
ATOM 2436 N N   . GLU A 1 341 ? 174.795 139.952 173.873 1.00 75.42  ? 341 GLU C N   1 
ATOM 2437 C CA  . GLU A 1 341 ? 173.786 140.965 174.164 1.00 75.42  ? 341 GLU C CA  1 
ATOM 2438 C C   . GLU A 1 341 ? 174.324 141.980 175.162 1.00 75.42  ? 341 GLU C C   1 
ATOM 2439 O O   . GLU A 1 341 ? 174.107 143.189 175.023 1.00 75.42  ? 341 GLU C O   1 
ATOM 2440 C CB  . GLU A 1 341 ? 172.507 140.319 174.701 1.00 75.42  ? 341 GLU C CB  1 
ATOM 2441 C CG  . GLU A 1 341 ? 171.496 139.923 173.640 1.00 75.42  ? 341 GLU C CG  1 
ATOM 2442 C CD  . GLU A 1 341 ? 171.592 138.466 173.247 1.00 75.42  ? 341 GLU C CD  1 
ATOM 2443 O OE1 . GLU A 1 341 ? 170.553 137.884 172.871 1.00 75.42  ? 341 GLU C OE1 1 
ATOM 2444 O OE2 . GLU A 1 341 ? 172.696 137.896 173.330 1.00 75.42  ? 341 GLU C OE2 1 
ATOM 2445 N N   . ALA A 1 342 ? 175.030 141.496 176.184 1.00 69.06  ? 342 ALA C N   1 
ATOM 2446 C CA  . ALA A 1 342 ? 175.546 142.383 177.219 1.00 69.06  ? 342 ALA C CA  1 
ATOM 2447 C C   . ALA A 1 342 ? 176.561 143.369 176.656 1.00 69.06  ? 342 ALA C C   1 
ATOM 2448 O O   . ALA A 1 342 ? 176.531 144.560 176.988 1.00 69.06  ? 342 ALA C O   1 
ATOM 2449 C CB  . ALA A 1 342 ? 176.164 141.557 178.345 1.00 69.06  ? 342 ALA C CB  1 
ATOM 2450 N N   . ASP A 1 343 ? 177.470 142.893 175.802 1.00 73.63  ? 343 ASP C N   1 
ATOM 2451 C CA  . ASP A 1 343 ? 178.470 143.779 175.218 1.00 73.63  ? 343 ASP C CA  1 
ATOM 2452 C C   . ASP A 1 343 ? 177.852 144.826 174.302 1.00 73.63  ? 343 ASP C C   1 
ATOM 2453 O O   . ASP A 1 343 ? 178.299 145.977 174.310 1.00 73.63  ? 343 ASP C O   1 
ATOM 2454 C CB  . ASP A 1 343 ? 179.512 142.973 174.447 1.00 73.63  ? 343 ASP C CB  1 
ATOM 2455 C CG  . ASP A 1 343 ? 180.821 143.717 174.293 1.00 73.63  ? 343 ASP C CG  1 
ATOM 2456 O OD1 . ASP A 1 343 ? 181.130 144.557 175.163 1.00 73.63  ? 343 ASP C OD1 1 
ATOM 2457 O OD2 . ASP A 1 343 ? 181.537 143.467 173.301 1.00 73.63  ? 343 ASP C OD2 1 
ATOM 2458 N N   . ALA A 1 344 ? 176.841 144.456 173.518 1.00 71.83  ? 344 ALA C N   1 
ATOM 2459 C CA  . ALA A 1 344 ? 176.150 145.400 172.654 1.00 71.83  ? 344 ALA C CA  1 
ATOM 2460 C C   . ALA A 1 344 ? 175.356 146.440 173.430 1.00 71.83  ? 344 ALA C C   1 
ATOM 2461 O O   . ALA A 1 344 ? 175.227 147.575 172.957 1.00 71.83  ? 344 ALA C O   1 
ATOM 2462 C CB  . ALA A 1 344 ? 175.213 144.656 171.695 1.00 71.83  ? 344 ALA C CB  1 
ATOM 2463 N N   . PHE A 1 345 ? 174.830 146.083 174.603 1.00 62.15  ? 345 PHE C N   1 
ATOM 2464 C CA  . PHE A 1 345 ? 174.114 147.049 175.429 1.00 62.15  ? 345 PHE C CA  1 
ATOM 2465 C C   . PHE A 1 345 ? 175.022 148.206 175.821 1.00 62.15  ? 345 PHE C C   1 
ATOM 2466 O O   . PHE A 1 345 ? 174.642 149.376 175.700 1.00 62.15  ? 345 PHE C O   1 
ATOM 2467 C CB  . PHE A 1 345 ? 173.557 146.351 176.670 1.00 62.15  ? 345 PHE C CB  1 
ATOM 2468 C CG  . PHE A 1 345 ? 172.378 147.046 177.295 1.00 62.15  ? 345 PHE C CG  1 
ATOM 2469 C CD1 . PHE A 1 345 ? 172.046 148.344 176.957 1.00 62.15  ? 345 PHE C CD1 1 
ATOM 2470 C CD2 . PHE A 1 345 ? 171.602 146.392 178.232 1.00 62.15  ? 345 PHE C CD2 1 
ATOM 2471 C CE1 . PHE A 1 345 ? 170.967 148.968 177.543 1.00 62.15  ? 345 PHE C CE1 1 
ATOM 2472 C CE2 . PHE A 1 345 ? 170.525 147.013 178.818 1.00 62.15  ? 345 PHE C CE2 1 
ATOM 2473 C CZ  . PHE A 1 345 ? 170.206 148.302 178.472 1.00 62.15  ? 345 PHE C CZ  1 
ATOM 2474 N N   . ARG A 1 346 ? 176.232 147.903 176.276 1.00 64.35  ? 346 ARG C N   1 
ATOM 2475 C CA  . ARG A 1 346 ? 177.175 148.935 176.674 1.00 64.35  ? 346 ARG C CA  1 
ATOM 2476 C C   . ARG A 1 346 ? 177.997 149.465 175.509 1.00 64.35  ? 346 ARG C C   1 
ATOM 2477 O O   . ARG A 1 346 ? 178.805 150.379 175.702 1.00 64.35  ? 346 ARG C O   1 
ATOM 2478 C CB  . ARG A 1 346 ? 178.091 148.417 177.781 1.00 64.35  ? 346 ARG C CB  1 
ATOM 2479 C CG  . ARG A 1 346 ? 177.331 147.883 178.978 1.00 64.35  ? 346 ARG C CG  1 
ATOM 2480 C CD  . ARG A 1 346 ? 178.158 147.991 180.242 1.00 64.35  ? 346 ARG C CD  1 
ATOM 2481 N NE  . ARG A 1 346 ? 179.072 149.125 180.203 1.00 64.35  ? 346 ARG C NE  1 
ATOM 2482 C CZ  . ARG A 1 346 ? 178.711 150.387 180.390 1.00 64.35  ? 346 ARG C CZ  1 
ATOM 2483 N NH1 . ARG A 1 346 ? 177.458 150.715 180.658 1.00 64.35  ? 346 ARG C NH1 1 
ATOM 2484 N NH2 . ARG A 1 346 ? 179.630 151.343 180.301 1.00 64.35  ? 346 ARG C NH2 1 
ATOM 2485 N N   . LYS A 1 347 ? 177.810 148.919 174.308 1.00 69.68  ? 347 LYS C N   1 
ATOM 2486 C CA  . LYS A 1 347 ? 178.437 149.501 173.128 1.00 69.68  ? 347 LYS C CA  1 
ATOM 2487 C C   . LYS A 1 347 ? 177.775 150.827 172.766 1.00 69.68  ? 347 LYS C C   1 
ATOM 2488 O O   . LYS A 1 347 ? 178.455 151.805 172.439 1.00 69.68  ? 347 LYS C O   1 
ATOM 2489 C CB  . LYS A 1 347 ? 178.367 148.519 171.956 1.00 69.68  ? 347 LYS C CB  1 
ATOM 2490 C CG  . LYS A 1 347 ? 178.687 149.132 170.599 1.00 69.68  ? 347 LYS C CG  1 
ATOM 2491 C CD  . LYS A 1 347 ? 180.085 149.732 170.565 1.00 69.68  ? 347 LYS C CD  1 
ATOM 2492 C CE  . LYS A 1 347 ? 180.475 150.142 169.155 1.00 69.68  ? 347 LYS C CE  1 
ATOM 2493 N NZ  . LYS A 1 347 ? 179.950 149.193 168.136 1.00 69.68  ? 347 LYS C NZ  1 
ATOM 2494 N N   . PHE A 1 348 ? 176.444 150.877 172.832 1.00 67.91  ? 348 PHE C N   1 
ATOM 2495 C CA  . PHE A 1 348 ? 175.707 152.081 172.472 1.00 67.91  ? 348 PHE C CA  1 
ATOM 2496 C C   . PHE A 1 348 ? 175.243 152.880 173.681 1.00 67.91  ? 348 PHE C C   1 
ATOM 2497 O O   . PHE A 1 348 ? 175.095 154.104 173.584 1.00 67.91  ? 348 PHE C O   1 
ATOM 2498 C CB  . PHE A 1 348 ? 174.501 151.717 171.605 1.00 67.91  ? 348 PHE C CB  1 
ATOM 2499 C CG  . PHE A 1 348 ? 174.867 151.315 170.212 1.00 67.91  ? 348 PHE C CG  1 
ATOM 2500 C CD1 . PHE A 1 348 ? 175.890 151.962 169.542 1.00 67.91  ? 348 PHE C CD1 1 
ATOM 2501 C CD2 . PHE A 1 348 ? 174.195 150.292 169.571 1.00 67.91  ? 348 PHE C CD2 1 
ATOM 2502 C CE1 . PHE A 1 348 ? 176.235 151.597 168.258 1.00 67.91  ? 348 PHE C CE1 1 
ATOM 2503 C CE2 . PHE A 1 348 ? 174.537 149.922 168.286 1.00 67.91  ? 348 PHE C CE2 1 
ATOM 2504 C CZ  . PHE A 1 348 ? 175.557 150.576 167.628 1.00 67.91  ? 348 PHE C CZ  1 
ATOM 2505 N N   . PHE A 1 349 ? 175.006 152.221 174.812 1.00 59.72  ? 349 PHE C N   1 
ATOM 2506 C CA  . PHE A 1 349 ? 174.652 152.902 176.052 1.00 59.72  ? 349 PHE C CA  1 
ATOM 2507 C C   . PHE A 1 349 ? 175.877 152.952 176.953 1.00 59.72  ? 349 PHE C C   1 
ATOM 2508 O O   . PHE A 1 349 ? 176.344 151.905 177.426 1.00 59.72  ? 349 PHE C O   1 
ATOM 2509 C CB  . PHE A 1 349 ? 173.489 152.192 176.745 1.00 59.72  ? 349 PHE C CB  1 
ATOM 2510 C CG  . PHE A 1 349 ? 172.174 152.394 176.056 1.00 59.72  ? 349 PHE C CG  1 
ATOM 2511 C CD1 . PHE A 1 349 ? 171.573 153.639 176.045 1.00 59.72  ? 349 PHE C CD1 1 
ATOM 2512 C CD2 . PHE A 1 349 ? 171.561 151.355 175.384 1.00 59.72  ? 349 PHE C CD2 1 
ATOM 2513 C CE1 . PHE A 1 349 ? 170.369 153.834 175.404 1.00 59.72  ? 349 PHE C CE1 1 
ATOM 2514 C CE2 . PHE A 1 349 ? 170.358 151.543 174.741 1.00 59.72  ? 349 PHE C CE2 1 
ATOM 2515 C CZ  . PHE A 1 349 ? 169.761 152.785 174.748 1.00 59.72  ? 349 PHE C CZ  1 
ATOM 2516 N N   . PRO A 1 350 ? 176.425 154.134 177.231 1.00 59.69  ? 350 PRO C N   1 
ATOM 2517 C CA  . PRO A 1 350 ? 177.791 154.193 177.769 1.00 59.69  ? 350 PRO C CA  1 
ATOM 2518 C C   . PRO A 1 350 ? 177.900 153.850 179.242 1.00 59.69  ? 350 PRO C C   1 
ATOM 2519 O O   . PRO A 1 350 ? 178.949 153.351 179.663 1.00 59.69  ? 350 PRO C O   1 
ATOM 2520 C CB  . PRO A 1 350 ? 178.214 155.645 177.499 1.00 59.69  ? 350 PRO C CB  1 
ATOM 2521 C CG  . PRO A 1 350 ? 176.976 156.374 177.013 1.00 59.69  ? 350 PRO C CG  1 
ATOM 2522 C CD  . PRO A 1 350 ? 175.802 155.461 177.133 1.00 59.69  ? 350 PRO C CD  1 
ATOM 2523 N N   . SER A 1 351 ? 176.866 154.108 180.053 1.00 57.17  ? 351 SER C N   1 
ATOM 2524 C CA  . SER A 1 351 ? 177.049 153.931 181.490 1.00 57.17  ? 351 SER C CA  1 
ATOM 2525 C C   . SER A 1 351 ? 175.852 153.317 182.212 1.00 57.17  ? 351 SER C C   1 
ATOM 2526 O O   . SER A 1 351 ? 175.852 153.294 183.448 1.00 57.17  ? 351 SER C O   1 
ATOM 2527 C CB  . SER A 1 351 ? 177.383 155.277 182.145 1.00 57.17  ? 351 SER C CB  1 
ATOM 2528 O OG  . SER A 1 351 ? 176.280 156.164 182.080 1.00 57.17  ? 351 SER C OG  1 
ATOM 2529 N N   . VAL A 1 352 ? 174.843 152.820 181.505 1.00 50.25  ? 352 VAL C N   1 
ATOM 2530 C CA  . VAL A 1 352 ? 173.687 152.232 182.177 1.00 50.25  ? 352 VAL C CA  1 
ATOM 2531 C C   . VAL A 1 352 ? 174.057 150.841 182.676 1.00 50.25  ? 352 VAL C C   1 
ATOM 2532 O O   . VAL A 1 352 ? 174.838 150.134 182.023 1.00 50.25  ? 352 VAL C O   1 
ATOM 2533 C CB  . VAL A 1 352 ? 172.458 152.192 181.256 1.00 50.25  ? 352 VAL C CB  1 
ATOM 2534 C CG1 . VAL A 1 352 ? 172.163 153.580 180.714 1.00 50.25  ? 352 VAL C CG1 1 
ATOM 2535 C CG2 . VAL A 1 352 ? 172.663 151.207 180.122 1.00 50.25  ? 352 VAL C CG2 1 
ATOM 2536 N N   . PRO A 1 353 ? 173.557 150.420 183.833 1.00 45.67  ? 353 PRO C N   1 
ATOM 2537 C CA  . PRO A 1 353 ? 173.818 149.051 184.293 1.00 45.67  ? 353 PRO C CA  1 
ATOM 2538 C C   . PRO A 1 353 ? 172.914 148.044 183.603 1.00 45.67  ? 353 PRO C C   1 
ATOM 2539 O O   . PRO A 1 353 ? 172.123 148.416 182.731 1.00 45.67  ? 353 PRO C O   1 
ATOM 2540 C CB  . PRO A 1 353 ? 173.539 149.133 185.798 1.00 45.67  ? 353 PRO C CB  1 
ATOM 2541 C CG  . PRO A 1 353 ? 172.538 150.227 185.915 1.00 45.67  ? 353 PRO C CG  1 
ATOM 2542 C CD  . PRO A 1 353 ? 172.911 151.238 184.872 1.00 45.67  ? 353 PRO C CD  1 
ATOM 2543 N N   . LEU A 1 354 ? 173.015 146.772 183.978 1.00 47.85  ? 354 LEU C N   1 
ATOM 2544 C CA  . LEU A 1 354 ? 172.216 145.730 183.342 1.00 47.85  ? 354 LEU C CA  1 
ATOM 2545 C C   . LEU A 1 354 ? 171.953 144.625 184.353 1.00 47.85  ? 354 LEU C C   1 
ATOM 2546 O O   . LEU A 1 354 ? 172.877 144.196 185.050 1.00 47.85  ? 354 LEU C O   1 
ATOM 2547 C CB  . LEU A 1 354 ? 172.932 145.189 182.098 1.00 47.85  ? 354 LEU C CB  1 
ATOM 2548 C CG  . LEU A 1 354 ? 172.526 143.888 181.401 1.00 47.85  ? 354 LEU C CG  1 
ATOM 2549 C CD1 . LEU A 1 354 ? 173.041 143.904 179.983 1.00 47.85  ? 354 LEU C CD1 1 
ATOM 2550 C CD2 . LEU A 1 354 ? 173.099 142.686 182.109 1.00 47.85  ? 354 LEU C CD2 1 
ATOM 2551 N N   . PHE A 1 355 ? 170.701 144.181 184.442 1.00 48.92  ? 355 PHE C N   1 
ATOM 2552 C CA  . PHE A 1 355 ? 170.313 143.067 185.296 1.00 48.92  ? 355 PHE C CA  1 
ATOM 2553 C C   . PHE A 1 355 ? 169.163 142.304 184.658 1.00 48.92  ? 355 PHE C C   1 
ATOM 2554 O O   . PHE A 1 355 ? 168.165 142.901 184.250 1.00 48.92  ? 355 PHE C O   1 
ATOM 2555 C CB  . PHE A 1 355 ? 169.901 143.548 186.689 1.00 48.92  ? 355 PHE C CB  1 
ATOM 2556 C CG  . PHE A 1 355 ? 170.958 144.340 187.391 1.00 48.92  ? 355 PHE C CG  1 
ATOM 2557 C CD1 . PHE A 1 355 ? 171.943 143.701 188.122 1.00 48.92  ? 355 PHE C CD1 1 
ATOM 2558 C CD2 . PHE A 1 355 ? 170.981 145.720 187.307 1.00 48.92  ? 355 PHE C CD2 1 
ATOM 2559 C CE1 . PHE A 1 355 ? 172.924 144.421 188.765 1.00 48.92  ? 355 PHE C CE1 1 
ATOM 2560 C CE2 . PHE A 1 355 ? 171.958 146.446 187.949 1.00 48.92  ? 355 PHE C CE2 1 
ATOM 2561 C CZ  . PHE A 1 355 ? 172.933 145.794 188.678 1.00 48.92  ? 355 PHE C CZ  1 
ATOM 2562 N N   . GLY A 1 356 ? 169.295 140.982 184.584 1.00 44.65  ? 356 GLY C N   1 
ATOM 2563 C CA  . GLY A 1 356 ? 168.243 140.176 183.992 1.00 44.65  ? 356 GLY C CA  1 
ATOM 2564 C C   . GLY A 1 356 ? 168.509 138.705 184.203 1.00 44.65  ? 356 GLY C C   1 
ATOM 2565 O O   . GLY A 1 356 ? 169.596 138.301 184.621 1.00 44.65  ? 356 GLY C O   1 
ATOM 2566 N N   . PHE A 1 357 ? 167.497 137.898 183.898 1.00 49.54  ? 357 PHE C N   1 
ATOM 2567 C CA  . PHE A 1 357 ? 167.560 136.465 184.136 1.00 49.54  ? 357 PHE C CA  1 
ATOM 2568 C C   . PHE A 1 357 ? 167.365 135.703 182.836 1.00 49.54  ? 357 PHE C C   1 
ATOM 2569 O O   . PHE A 1 357 ? 166.964 136.276 181.819 1.00 49.54  ? 357 PHE C O   1 
ATOM 2570 C CB  . PHE A 1 357 ? 166.502 136.011 185.145 1.00 49.54  ? 357 PHE C CB  1 
ATOM 2571 C CG  . PHE A 1 357 ? 165.099 136.029 184.610 1.00 49.54  ? 357 PHE C CG  1 
ATOM 2572 C CD1 . PHE A 1 357 ? 164.317 137.163 184.703 1.00 49.54  ? 357 PHE C CD1 1 
ATOM 2573 C CD2 . PHE A 1 357 ? 164.556 134.896 184.027 1.00 49.54  ? 357 PHE C CD2 1 
ATOM 2574 C CE1 . PHE A 1 357 ? 163.023 137.168 184.214 1.00 49.54  ? 357 PHE C CE1 1 
ATOM 2575 C CE2 . PHE A 1 357 ? 163.270 134.899 183.534 1.00 49.54  ? 357 PHE C CE2 1 
ATOM 2576 C CZ  . PHE A 1 357 ? 162.502 136.036 183.628 1.00 49.54  ? 357 PHE C CZ  1 
ATOM 2577 N N   . PHE A 1 358 ? 167.648 134.406 182.886 1.00 54.14  ? 358 PHE C N   1 
ATOM 2578 C CA  . PHE A 1 358 ? 167.350 133.471 181.811 1.00 54.14  ? 358 PHE C CA  1 
ATOM 2579 C C   . PHE A 1 358 ? 166.185 132.594 182.244 1.00 54.14  ? 358 PHE C C   1 
ATOM 2580 O O   . PHE A 1 358 ? 166.210 132.027 183.340 1.00 54.14  ? 358 PHE C O   1 
ATOM 2581 C CB  . PHE A 1 358 ? 168.566 132.605 181.484 1.00 54.14  ? 358 PHE C CB  1 
ATOM 2582 C CG  . PHE A 1 358 ? 169.429 133.161 180.398 1.00 54.14  ? 358 PHE C CG  1 
ATOM 2583 C CD1 . PHE A 1 358 ? 169.120 132.935 179.073 1.00 54.14  ? 358 PHE C CD1 1 
ATOM 2584 C CD2 . PHE A 1 358 ? 170.553 133.903 180.700 1.00 54.14  ? 358 PHE C CD2 1 
ATOM 2585 C CE1 . PHE A 1 358 ? 169.910 133.442 178.072 1.00 54.14  ? 358 PHE C CE1 1 
ATOM 2586 C CE2 . PHE A 1 358 ? 171.347 134.409 179.699 1.00 54.14  ? 358 PHE C CE2 1 
ATOM 2587 C CZ  . PHE A 1 358 ? 171.023 134.178 178.385 1.00 54.14  ? 358 PHE C CZ  1 
ATOM 2588 N N   . GLY A 1 359 ? 165.174 132.482 181.394 1.00 55.70  ? 359 GLY C N   1 
ATOM 2589 C CA  . GLY A 1 359 ? 163.985 131.759 181.789 1.00 55.70  ? 359 GLY C CA  1 
ATOM 2590 C C   . GLY A 1 359 ? 163.388 130.989 180.635 1.00 55.70  ? 359 GLY C C   1 
ATOM 2591 O O   . GLY A 1 359 ? 163.889 131.024 179.511 1.00 55.70  ? 359 GLY C O   1 
ATOM 2592 N N   . ASN A 1 360 ? 162.295 130.286 180.939 1.00 61.31  ? 360 ASN C N   1 
ATOM 2593 C CA  . ASN A 1 360 ? 161.589 129.457 179.970 1.00 61.31  ? 360 ASN C CA  1 
ATOM 2594 C C   . ASN A 1 360 ? 160.401 130.170 179.341 1.00 61.31  ? 360 ASN C C   1 
ATOM 2595 O O   . ASN A 1 360 ? 159.513 129.513 178.783 1.00 61.31  ? 360 ASN C O   1 
ATOM 2596 C CB  . ASN A 1 360 ? 161.130 128.156 180.630 1.00 61.31  ? 360 ASN C CB  1 
ATOM 2597 C CG  . ASN A 1 360 ? 162.191 127.551 181.518 1.00 61.31  ? 360 ASN C CG  1 
ATOM 2598 O OD1 . ASN A 1 360 ? 162.549 128.116 182.550 1.00 61.31  ? 360 ASN C OD1 1 
ATOM 2599 N ND2 . ASN A 1 360 ? 162.701 126.391 181.123 1.00 61.31  ? 360 ASN C ND2 1 
ATOM 2600 N N   . GLY A 1 361 ? 160.357 131.496 179.414 1.00 57.41  ? 361 GLY C N   1 
ATOM 2601 C CA  . GLY A 1 361 ? 159.231 132.235 178.881 1.00 57.41  ? 361 GLY C CA  1 
ATOM 2602 C C   . GLY A 1 361 ? 159.540 133.699 178.664 1.00 57.41  ? 361 GLY C C   1 
ATOM 2603 O O   . GLY A 1 361 ? 160.451 134.247 179.289 1.00 57.41  ? 361 GLY C O   1 
ATOM 2604 N N   . GLU A 1 362 ? 158.784 134.347 177.780 1.00 59.06  ? 362 GLU C N   1 
ATOM 2605 C CA  . GLU A 1 362 ? 159.057 135.720 177.392 1.00 59.06  ? 362 GLU C CA  1 
ATOM 2606 C C   . GLU A 1 362 ? 157.773 136.534 177.402 1.00 59.06  ? 362 GLU C C   1 
ATOM 2607 O O   . GLU A 1 362 ? 156.714 136.058 176.985 1.00 59.06  ? 362 GLU C O   1 
ATOM 2608 C CB  . GLU A 1 362 ? 159.702 135.784 176.004 1.00 59.06  ? 362 GLU C CB  1 
ATOM 2609 C CG  . GLU A 1 362 ? 160.737 134.707 175.751 1.00 59.06  ? 362 GLU C CG  1 
ATOM 2610 C CD  . GLU A 1 362 ? 161.918 134.793 176.697 1.00 59.06  ? 362 GLU C CD  1 
ATOM 2611 O OE1 . GLU A 1 362 ? 162.641 133.788 176.826 1.00 59.06  ? 362 GLU C OE1 1 
ATOM 2612 O OE2 . GLU A 1 362 ? 162.143 135.868 177.293 1.00 59.06  ? 362 GLU C OE2 1 
ATOM 2613 N N   . ILE A 1 363 ? 157.881 137.769 177.887 1.00 55.10  ? 363 ILE C N   1 
ATOM 2614 C CA  . ILE A 1 363 ? 156.786 138.733 177.872 1.00 55.10  ? 363 ILE C CA  1 
ATOM 2615 C C   . ILE A 1 363 ? 157.344 140.066 177.396 1.00 55.10  ? 363 ILE C C   1 
ATOM 2616 O O   . ILE A 1 363 ? 158.407 140.496 177.855 1.00 55.10  ? 363 ILE C O   1 
ATOM 2617 C CB  . ILE A 1 363 ? 156.132 138.895 179.259 1.00 55.10  ? 363 ILE C CB  1 
ATOM 2618 C CG1 . ILE A 1 363 ? 155.755 137.535 179.852 1.00 55.10  ? 363 ILE C CG1 1 
ATOM 2619 C CG2 . ILE A 1 363 ? 154.913 139.796 179.171 1.00 55.10  ? 363 ILE C CG2 1 
ATOM 2620 C CD1 . ILE A 1 363 ? 154.495 136.939 179.272 1.00 55.10  ? 363 ILE C CD1 1 
ATOM 2621 N N   . GLY A 1 364 ? 156.644 140.713 176.481 1.00 60.17  ? 364 GLY C N   1 
ATOM 2622 C CA  . GLY A 1 364 ? 157.048 142.030 176.025 1.00 60.17  ? 364 GLY C CA  1 
ATOM 2623 C C   . GLY A 1 364 ? 156.591 142.285 174.605 1.00 60.17  ? 364 GLY C C   1 
ATOM 2624 O O   . GLY A 1 364 ? 156.063 141.411 173.921 1.00 60.17  ? 364 GLY C O   1 
ATOM 2625 N N   . CYS A 1 365 ? 156.808 143.522 174.169 1.00 64.47  ? 365 CYS C N   1 
ATOM 2626 C CA  . CYS A 1 365 ? 156.453 143.957 172.824 1.00 64.47  ? 365 CYS C CA  1 
ATOM 2627 C C   . CYS A 1 365 ? 157.398 145.084 172.424 1.00 64.47  ? 365 CYS C C   1 
ATOM 2628 O O   . CYS A 1 365 ? 158.443 145.290 173.047 1.00 64.47  ? 365 CYS C O   1 
ATOM 2629 C CB  . CYS A 1 365 ? 154.984 144.389 172.768 1.00 64.47  ? 365 CYS C CB  1 
ATOM 2630 S SG  . CYS A 1 365 ? 154.468 145.436 174.149 1.00 64.47  ? 365 CYS C SG  1 
ATOM 2631 N N   . ASP A 1 366 ? 157.037 145.810 171.371 1.00 67.89  ? 366 ASP C N   1 
ATOM 2632 C CA  . ASP A 1 366 ? 157.723 147.036 170.984 1.00 67.89  ? 366 ASP C CA  1 
ATOM 2633 C C   . ASP A 1 366 ? 156.866 148.222 171.397 1.00 67.89  ? 366 ASP C C   1 
ATOM 2634 O O   . ASP A 1 366 ? 155.763 148.406 170.872 1.00 67.89  ? 366 ASP C O   1 
ATOM 2635 C CB  . ASP A 1 366 ? 157.990 147.076 169.478 1.00 67.89  ? 366 ASP C CB  1 
ATOM 2636 C CG  . ASP A 1 366 ? 158.630 145.805 168.965 1.00 67.89  ? 366 ASP C CG  1 
ATOM 2637 O OD1 . ASP A 1 366 ? 159.869 145.687 169.049 1.00 67.89  ? 366 ASP C OD1 1 
ATOM 2638 O OD2 . ASP A 1 366 ? 157.897 144.927 168.465 1.00 67.89  ? 366 ASP C OD2 1 
ATOM 2639 N N   . ARG A 1 367 ? 157.372 149.024 172.332 1.00 76.28  ? 367 ARG C N   1 
ATOM 2640 C CA  . ARG A 1 367 ? 156.585 150.119 172.885 1.00 76.28  ? 367 ARG C CA  1 
ATOM 2641 C C   . ARG A 1 367 ? 157.458 151.094 173.662 1.00 76.28  ? 367 ARG C C   1 
ATOM 2642 O O   . ARG A 1 367 ? 158.366 150.681 174.388 1.00 76.28  ? 367 ARG C O   1 
ATOM 2643 C CB  . ARG A 1 367 ? 155.482 149.569 173.789 1.00 76.28  ? 367 ARG C CB  1 
ATOM 2644 C CG  . ARG A 1 367 ? 154.490 150.608 174.267 1.00 76.28  ? 367 ARG C CG  1 
ATOM 2645 C CD  . ARG A 1 367 ? 153.423 149.978 175.142 1.00 76.28  ? 367 ARG C CD  1 
ATOM 2646 N NE  . ARG A 1 367 ? 153.239 148.564 174.843 1.00 76.28  ? 367 ARG C NE  1 
ATOM 2647 C CZ  . ARG A 1 367 ? 152.130 147.885 175.102 1.00 76.28  ? 367 ARG C CZ  1 
ATOM 2648 N NH1 . ARG A 1 367 ? 151.080 148.464 175.658 1.00 76.28  ? 367 ARG C NH1 1 
ATOM 2649 N NH2 . ARG A 1 367 ? 152.073 146.594 174.792 1.00 76.28  ? 367 ARG C NH2 1 
ATOM 2650 N N   . ILE A 1 368 ? 157.191 152.388 173.514 1.00 50.63  ? 368 ILE C N   1 
ATOM 2651 C CA  . ILE A 1 368 ? 157.889 153.437 174.248 1.00 50.63  ? 368 ILE C CA  1 
ATOM 2652 C C   . ILE A 1 368 ? 156.828 154.297 174.916 1.00 50.63  ? 368 ILE C C   1 
ATOM 2653 O O   . ILE A 1 368 ? 155.914 154.794 174.246 1.00 50.63  ? 368 ILE C O   1 
ATOM 2654 C CB  . ILE A 1 368 ? 158.783 154.289 173.340 1.00 50.63  ? 368 ILE C CB  1 
ATOM 2655 C CG1 . ILE A 1 368 ? 159.578 153.410 172.378 1.00 50.63  ? 368 ILE C CG1 1 
ATOM 2656 C CG2 . ILE A 1 368 ? 159.718 155.142 174.173 1.00 50.63  ? 368 ILE C CG2 1 
ATOM 2657 C CD1 . ILE A 1 368 ? 160.720 152.678 173.029 1.00 50.63  ? 368 ILE C CD1 1 
ATOM 2658 N N   . VAL A 1 369 ? 156.941 154.477 176.228 1.00 46.64  ? 369 VAL C N   1 
ATOM 2659 C CA  . VAL A 1 369 ? 156.062 155.362 176.981 1.00 46.64  ? 369 VAL C CA  1 
ATOM 2660 C C   . VAL A 1 369 ? 156.920 156.340 177.765 1.00 46.64  ? 369 VAL C C   1 
ATOM 2661 O O   . VAL A 1 369 ? 157.809 155.932 178.520 1.00 46.64  ? 369 VAL C O   1 
ATOM 2662 C CB  . VAL A 1 369 ? 155.129 154.581 177.919 1.00 46.64  ? 369 VAL C CB  1 
ATOM 2663 C CG1 . VAL A 1 369 ? 154.376 155.534 178.829 1.00 46.64  ? 369 VAL C CG1 1 
ATOM 2664 C CG2 . VAL A 1 369 ? 154.164 153.736 177.115 1.00 46.64  ? 369 VAL C CG2 1 
ATOM 2665 N N   . THR A 1 370 ? 156.647 157.630 177.589 1.00 41.65  ? 370 THR C N   1 
ATOM 2666 C CA  . THR A 1 370 ? 157.367 158.682 178.292 1.00 41.65  ? 370 THR C CA  1 
ATOM 2667 C C   . THR A 1 370 ? 156.363 159.676 178.854 1.00 41.65  ? 370 THR C C   1 
ATOM 2668 O O   . THR A 1 370 ? 155.165 159.387 178.913 1.00 41.65  ? 370 THR C O   1 
ATOM 2669 C CB  . THR A 1 370 ? 158.357 159.405 177.374 1.00 41.65  ? 370 THR C CB  1 
ATOM 2670 O OG1 . THR A 1 370 ? 157.649 160.333 176.543 1.00 41.65  ? 370 THR C OG1 1 
ATOM 2671 C CG2 . THR A 1 370 ? 159.116 158.423 176.496 1.00 41.65  ? 370 THR C CG2 1 
ATOM 2672 N N   . GLY A 1 371 ? 156.841 160.839 179.282 1.00 50.64  ? 371 GLY C N   1 
ATOM 2673 C CA  . GLY A 1 371 ? 155.959 161.864 179.797 1.00 50.64  ? 371 GLY C CA  1 
ATOM 2674 C C   . GLY A 1 371 ? 154.969 162.382 178.773 1.00 50.64  ? 371 GLY C C   1 
ATOM 2675 O O   . GLY A 1 371 ? 153.906 162.892 179.138 1.00 50.64  ? 371 GLY C O   1 
ATOM 2676 N N   . ASN A 1 372 ? 155.302 162.266 177.488 1.00 48.27  ? 372 ASN C N   1 
ATOM 2677 C CA  . ASN A 1 372 ? 154.427 162.794 176.450 1.00 48.27  ? 372 ASN C CA  1 
ATOM 2678 C C   . ASN A 1 372 ? 153.855 161.716 175.536 1.00 48.27  ? 372 ASN C C   1 
ATOM 2679 O O   . ASN A 1 372 ? 152.633 161.591 175.412 1.00 48.27  ? 372 ASN C O   1 
ATOM 2680 C CB  . ASN A 1 372 ? 155.172 163.834 175.613 1.00 48.27  ? 372 ASN C CB  1 
ATOM 2681 C CG  . ASN A 1 372 ? 156.079 164.710 176.447 1.00 48.27  ? 372 ASN C CG  1 
ATOM 2682 O OD1 . ASN A 1 372 ? 155.782 165.007 177.604 1.00 48.27  ? 372 ASN C OD1 1 
ATOM 2683 N ND2 . ASN A 1 372 ? 157.192 165.137 175.862 1.00 48.27  ? 372 ASN C ND2 1 
ATOM 2684 N N   . PHE A 1 373 ? 154.716 160.925 174.901 1.00 60.32  ? 373 PHE C N   1 
ATOM 2685 C CA  . PHE A 1 373 ? 154.262 160.114 173.779 1.00 60.32  ? 373 PHE C CA  1 
ATOM 2686 C C   . PHE A 1 373 ? 154.160 158.643 174.155 1.00 60.32  ? 373 PHE C C   1 
ATOM 2687 O O   . PHE A 1 373 ? 154.849 158.161 175.057 1.00 60.32  ? 373 PHE C O   1 
ATOM 2688 C CB  . PHE A 1 373 ? 155.199 160.309 172.581 1.00 60.32  ? 373 PHE C CB  1 
ATOM 2689 C CG  . PHE A 1 373 ? 156.509 159.578 172.685 1.00 60.32  ? 373 PHE C CG  1 
ATOM 2690 C CD1 . PHE A 1 373 ? 156.603 158.229 172.379 1.00 60.32  ? 373 PHE C CD1 1 
ATOM 2691 C CD2 . PHE A 1 373 ? 157.666 160.265 172.991 1.00 60.32  ? 373 PHE C CD2 1 
ATOM 2692 C CE1 . PHE A 1 373 ? 157.814 157.572 172.454 1.00 60.32  ? 373 PHE C CE1 1 
ATOM 2693 C CE2 . PHE A 1 373 ? 158.878 159.616 173.068 1.00 60.32  ? 373 PHE C CE2 1 
ATOM 2694 C CZ  . PHE A 1 373 ? 158.953 158.267 172.795 1.00 60.32  ? 373 PHE C CZ  1 
ATOM 2695 N N   . ILE A 1 374 ? 153.277 157.934 173.457 1.00 49.36  ? 374 ILE C N   1 
ATOM 2696 C CA  . ILE A 1 374 ? 153.113 156.492 173.585 1.00 49.36  ? 374 ILE C CA  1 
ATOM 2697 C C   . ILE A 1 374 ? 153.125 155.906 172.181 1.00 49.36  ? 374 ILE C C   1 
ATOM 2698 O O   . ILE A 1 374 ? 152.466 156.439 171.280 1.00 49.36  ? 374 ILE C O   1 
ATOM 2699 C CB  . ILE A 1 374 ? 151.814 156.121 174.316 1.00 49.36  ? 374 ILE C CB  1 
ATOM 2700 C CG1 . ILE A 1 374 ? 151.687 156.911 175.618 1.00 49.36  ? 374 ILE C CG1 1 
ATOM 2701 C CG2 . ILE A 1 374 ? 151.779 154.641 174.603 1.00 49.36  ? 374 ILE C CG2 1 
ATOM 2702 C CD1 . ILE A 1 374 ? 150.312 157.499 175.844 1.00 49.36  ? 374 ILE C CD1 1 
ATOM 2703 N N   . LEU A 1 375 ? 153.863 154.813 171.992 1.00 76.28  ? 375 LEU C N   1 
ATOM 2704 C CA  . LEU A 1 375 ? 154.070 154.254 170.660 1.00 76.28  ? 375 LEU C CA  1 
ATOM 2705 C C   . LEU A 1 375 ? 153.582 152.814 170.562 1.00 76.28  ? 375 LEU C C   1 
ATOM 2706 O O   . LEU A 1 375 ? 154.309 151.943 170.077 1.00 76.28  ? 375 LEU C O   1 
ATOM 2707 C CB  . LEU A 1 375 ? 155.548 154.333 170.277 1.00 76.28  ? 375 LEU C CB  1 
ATOM 2708 C CG  . LEU A 1 375 ? 155.872 154.369 168.784 1.00 76.28  ? 375 LEU C CG  1 
ATOM 2709 C CD1 . LEU A 1 375 ? 155.688 155.765 168.230 1.00 76.28  ? 375 LEU C CD1 1 
ATOM 2710 C CD2 . LEU A 1 375 ? 157.281 153.883 168.535 1.00 76.28  ? 375 LEU C CD2 1 
ATOM 2711 N N   . ARG A 1 376 ? 152.362 152.553 171.028 1.00 64.28  ? 376 ARG C N   1 
ATOM 2712 C CA  . ARG A 1 376 ? 151.827 151.199 171.063 1.00 64.28  ? 376 ARG C CA  1 
ATOM 2713 C C   . ARG A 1 376 ? 151.836 150.551 169.680 1.00 64.28  ? 376 ARG C C   1 
ATOM 2714 O O   . ARG A 1 376 ? 151.935 151.216 168.646 1.00 64.28  ? 376 ARG C O   1 
ATOM 2715 C CB  . ARG A 1 376 ? 150.396 151.199 171.598 1.00 64.28  ? 376 ARG C CB  1 
ATOM 2716 C CG  . ARG A 1 376 ? 150.148 152.160 172.735 1.00 64.28  ? 376 ARG C CG  1 
ATOM 2717 C CD  . ARG A 1 376 ? 148.690 152.142 173.156 1.00 64.28  ? 376 ARG C CD  1 
ATOM 2718 N NE  . ARG A 1 376 ? 147.803 151.893 172.026 1.00 64.28  ? 376 ARG C NE  1 
ATOM 2719 C CZ  . ARG A 1 376 ? 147.262 152.843 171.276 1.00 64.28  ? 376 ARG C CZ  1 
ATOM 2720 N NH1 . ARG A 1 376 ? 147.492 154.124 171.509 1.00 64.28  ? 376 ARG C NH1 1 
ATOM 2721 N NH2 . ARG A 1 376 ? 146.468 152.498 170.266 1.00 64.28  ? 376 ARG C NH2 1 
ATOM 2722 N N   . LYS A 1 377 ? 151.725 149.227 169.680 1.00 78.56  ? 377 LYS C N   1 
ATOM 2723 C CA  . LYS A 1 377 ? 151.563 148.426 168.470 1.00 78.56  ? 377 LYS C CA  1 
ATOM 2724 C C   . LYS A 1 377 ? 150.071 148.133 168.343 1.00 78.56  ? 377 LYS C C   1 
ATOM 2725 O O   . LYS A 1 377 ? 149.435 147.698 169.307 1.00 78.56  ? 377 LYS C O   1 
ATOM 2726 C CB  . LYS A 1 377 ? 152.392 147.148 168.549 1.00 78.56  ? 377 LYS C CB  1 
ATOM 2727 C CG  . LYS A 1 377 ? 151.981 146.060 167.573 1.00 78.56  ? 377 LYS C CG  1 
ATOM 2728 C CD  . LYS A 1 377 ? 152.972 145.956 166.425 1.00 78.56  ? 377 LYS C CD  1 
ATOM 2729 C CE  . LYS A 1 377 ? 152.670 144.759 165.537 1.00 78.56  ? 377 LYS C CE  1 
ATOM 2730 N NZ  . LYS A 1 377 ? 153.704 144.574 164.480 1.00 78.56  ? 377 LYS C NZ  1 
ATOM 2731 N N   . CYS A 1 378 ? 149.511 148.387 167.159 1.00 88.38  ? 378 CYS C N   1 
ATOM 2732 C CA  . CYS A 1 378 ? 148.066 148.310 166.963 1.00 88.38  ? 378 CYS C CA  1 
ATOM 2733 C C   . CYS A 1 378 ? 147.516 146.917 167.242 1.00 88.38  ? 378 CYS C C   1 
ATOM 2734 O O   . CYS A 1 378 ? 146.358 146.787 167.652 1.00 88.38  ? 378 CYS C O   1 
ATOM 2735 C CB  . CYS A 1 378 ? 147.695 148.753 165.548 1.00 88.38  ? 378 CYS C CB  1 
ATOM 2736 S SG  . CYS A 1 378 ? 147.628 150.547 165.352 1.00 88.38  ? 378 CYS C SG  1 
ATOM 2737 N N   . ASN A 1 379 ? 148.319 145.886 166.968 1.00 100.61 ? 379 ASN C N   1 
ATOM 2738 C CA  . ASN A 1 379 ? 148.128 144.508 167.446 1.00 100.61 ? 379 ASN C CA  1 
ATOM 2739 C C   . ASN A 1 379 ? 146.654 144.096 167.508 1.00 100.61 ? 379 ASN C C   1 
ATOM 2740 O O   . ASN A 1 379 ? 146.158 143.560 168.501 1.00 100.61 ? 379 ASN C O   1 
ATOM 2741 C CB  . ASN A 1 379 ? 148.848 144.309 168.790 1.00 100.61 ? 379 ASN C CB  1 
ATOM 2742 C CG  . ASN A 1 379 ? 148.183 145.035 169.970 1.00 100.61 ? 379 ASN C CG  1 
ATOM 2743 O OD1 . ASN A 1 379 ? 147.112 145.625 169.858 1.00 100.61 ? 379 ASN C OD1 1 
ATOM 2744 N ND2 . ASN A 1 379 ? 148.847 144.989 171.118 1.00 100.61 ? 379 ASN C ND2 1 
ATOM 2745 N N   . GLU A 1 380 ? 145.968 144.309 166.392 1.00 113.45 ? 380 GLU C N   1 
ATOM 2746 C CA  . GLU A 1 380 ? 144.514 144.256 166.351 1.00 113.45 ? 380 GLU C CA  1 
ATOM 2747 C C   . GLU A 1 380 ? 143.932 142.847 166.450 1.00 113.45 ? 380 GLU C C   1 
ATOM 2748 O O   . GLU A 1 380 ? 142.718 142.709 166.274 1.00 113.45 ? 380 GLU C O   1 
ATOM 2749 C CB  . GLU A 1 380 ? 144.003 144.915 165.067 1.00 113.45 ? 380 GLU C CB  1 
ATOM 2750 C CG  . GLU A 1 380 ? 144.923 145.975 164.489 1.00 113.45 ? 380 GLU C CG  1 
ATOM 2751 C CD  . GLU A 1 380 ? 144.293 146.715 163.325 1.00 113.45 ? 380 GLU C CD  1 
ATOM 2752 O OE1 . GLU A 1 380 ? 144.272 146.159 162.207 1.00 113.45 ? 380 GLU C OE1 1 
ATOM 2753 O OE2 . GLU A 1 380 ? 143.815 147.851 163.527 1.00 113.45 ? 380 GLU C OE2 1 
ATOM 2754 N N   . VAL A 1 381 ? 144.714 141.799 166.717 1.00 118.95 ? 381 VAL C N   1 
ATOM 2755 C CA  . VAL A 1 381 ? 144.096 140.478 166.644 1.00 118.95 ? 381 VAL C CA  1 
ATOM 2756 C C   . VAL A 1 381 ? 143.375 140.158 167.948 1.00 118.95 ? 381 VAL C C   1 
ATOM 2757 O O   . VAL A 1 381 ? 142.145 140.268 168.016 1.00 118.95 ? 381 VAL C O   1 
ATOM 2758 C CB  . VAL A 1 381 ? 145.142 139.398 166.318 1.00 118.95 ? 381 VAL C CB  1 
ATOM 2759 C CG1 . VAL A 1 381 ? 144.456 138.092 165.948 1.00 118.95 ? 381 VAL C CG1 1 
ATOM 2760 C CG2 . VAL A 1 381 ? 146.055 139.867 165.196 1.00 118.95 ? 381 VAL C CG2 1 
ATOM 2761 N N   . LYS A 1 382 ? 144.105 139.765 168.995 1.00 116.34 ? 382 LYS C N   1 
ATOM 2762 C CA  . LYS A 1 382 ? 143.597 139.979 170.346 1.00 116.34 ? 382 LYS C CA  1 
ATOM 2763 C C   . LYS A 1 382 ? 144.665 140.532 171.284 1.00 116.34 ? 382 LYS C C   1 
ATOM 2764 O O   . LYS A 1 382 ? 144.586 141.683 171.727 1.00 116.34 ? 382 LYS C O   1 
ATOM 2765 C CB  . LYS A 1 382 ? 143.025 138.670 170.902 1.00 116.34 ? 382 LYS C CB  1 
ATOM 2766 C CG  . LYS A 1 382 ? 142.748 138.653 172.408 1.00 116.34 ? 382 LYS C CG  1 
ATOM 2767 C CD  . LYS A 1 382 ? 141.889 139.824 172.869 1.00 116.34 ? 382 LYS C CD  1 
ATOM 2768 C CE  . LYS A 1 382 ? 141.549 139.698 174.346 1.00 116.34 ? 382 LYS C CE  1 
ATOM 2769 N NZ  . LYS A 1 382 ? 141.578 141.013 175.043 1.00 116.34 ? 382 LYS C NZ  1 
ATOM 2770 N N   . ASP A 1 383 ? 145.664 139.705 171.585 1.00 104.63 ? 383 ASP C N   1 
ATOM 2771 C CA  . ASP A 1 383 ? 146.761 140.047 172.484 1.00 104.63 ? 383 ASP C CA  1 
ATOM 2772 C C   . ASP A 1 383 ? 148.024 139.274 172.099 1.00 104.63 ? 383 ASP C C   1 
ATOM 2773 O O   . ASP A 1 383 ? 148.863 138.942 172.933 1.00 104.63 ? 383 ASP C O   1 
ATOM 2774 C CB  . ASP A 1 383 ? 146.358 139.782 173.933 1.00 104.63 ? 383 ASP C CB  1 
ATOM 2775 C CG  . ASP A 1 383 ? 146.899 140.826 174.886 1.00 104.63 ? 383 ASP C CG  1 
ATOM 2776 O OD1 . ASP A 1 383 ? 146.856 142.025 174.542 1.00 104.63 ? 383 ASP C OD1 1 
ATOM 2777 O OD2 . ASP A 1 383 ? 147.364 140.445 175.980 1.00 104.63 ? 383 ASP C OD2 1 
ATOM 2778 N N   . ASP A 1 384 ? 148.191 138.961 170.816 1.00 102.74 ? 384 ASP C N   1 
ATOM 2779 C CA  . ASP A 1 384 ? 149.213 138.015 170.385 1.00 102.74 ? 384 ASP C CA  1 
ATOM 2780 C C   . ASP A 1 384 ? 150.578 138.669 170.204 1.00 102.74 ? 384 ASP C C   1 
ATOM 2781 O O   . ASP A 1 384 ? 151.417 138.147 169.461 1.00 102.74 ? 384 ASP C O   1 
ATOM 2782 C CB  . ASP A 1 384 ? 148.782 137.323 169.091 1.00 102.74 ? 384 ASP C CB  1 
ATOM 2783 C CG  . ASP A 1 384 ? 148.394 138.306 168.006 1.00 102.74 ? 384 ASP C CG  1 
ATOM 2784 O OD1 . ASP A 1 384 ? 147.708 139.301 168.322 1.00 102.74 ? 384 ASP C OD1 1 
ATOM 2785 O OD2 . ASP A 1 384 ? 148.772 138.083 166.837 1.00 102.74 ? 384 ASP C OD2 1 
ATOM 2786 N N   . ASP A 1 385 ? 150.820 139.793 170.874 1.00 88.82  ? 385 ASP C N   1 
ATOM 2787 C CA  . ASP A 1 385 ? 152.052 140.557 170.731 1.00 88.82  ? 385 ASP C CA  1 
ATOM 2788 C C   . ASP A 1 385 ? 152.880 140.520 172.011 1.00 88.82  ? 385 ASP C C   1 
ATOM 2789 O O   . ASP A 1 385 ? 153.863 141.251 172.143 1.00 88.82  ? 385 ASP C O   1 
ATOM 2790 C CB  . ASP A 1 385 ? 151.730 142.000 170.352 1.00 88.82  ? 385 ASP C CB  1 
ATOM 2791 C CG  . ASP A 1 385 ? 151.018 142.743 171.467 1.00 88.82  ? 385 ASP C CG  1 
ATOM 2792 O OD1 . ASP A 1 385 ? 151.679 143.127 172.453 1.00 88.82  ? 385 ASP C OD1 1 
ATOM 2793 O OD2 . ASP A 1 385 ? 149.802 142.977 171.344 1.00 88.82  ? 385 ASP C OD2 1 
ATOM 2794 N N   . LEU A 1 386 ? 152.486 139.681 172.967 1.00 73.04  ? 386 LEU C N   1 
ATOM 2795 C CA  . LEU A 1 386 ? 153.132 139.670 174.273 1.00 73.04  ? 386 LEU C CA  1 
ATOM 2796 C C   . LEU A 1 386 ? 153.854 138.356 174.535 1.00 73.04  ? 386 LEU C C   1 
ATOM 2797 O O   . LEU A 1 386 ? 155.051 138.348 174.840 1.00 73.04  ? 386 LEU C O   1 
ATOM 2798 C CB  . LEU A 1 386 ? 152.103 139.934 175.373 1.00 73.04  ? 386 LEU C CB  1 
ATOM 2799 C CG  . LEU A 1 386 ? 151.706 141.394 175.587 1.00 73.04  ? 386 LEU C CG  1 
ATOM 2800 C CD1 . LEU A 1 386 ? 151.206 141.607 177.001 1.00 73.04  ? 386 LEU C CD1 1 
ATOM 2801 C CD2 . LEU A 1 386 ? 152.882 142.307 175.302 1.00 73.04  ? 386 LEU C CD2 1 
ATOM 2802 N N   . PHE A 1 387 ? 153.140 137.241 174.410 1.00 71.21  ? 387 PHE C N   1 
ATOM 2803 C CA  . PHE A 1 387 ? 153.718 135.939 174.715 1.00 71.21  ? 387 PHE C CA  1 
ATOM 2804 C C   . PHE A 1 387 ? 154.531 135.396 173.552 1.00 71.21  ? 387 PHE C C   1 
ATOM 2805 O O   . PHE A 1 387 ? 154.015 134.657 172.708 1.00 71.21  ? 387 PHE C O   1 
ATOM 2806 C CB  . PHE A 1 387 ? 152.630 134.940 175.115 1.00 71.21  ? 387 PHE C CB  1 
ATOM 2807 C CG  . PHE A 1 387 ? 151.837 135.357 176.315 1.00 71.21  ? 387 PHE C CG  1 
ATOM 2808 C CD1 . PHE A 1 387 ? 150.945 136.412 176.257 1.00 71.21  ? 387 PHE C CD1 1 
ATOM 2809 C CD2 . PHE A 1 387 ? 151.997 134.688 177.513 1.00 71.21  ? 387 PHE C CD2 1 
ATOM 2810 C CE1 . PHE A 1 387 ? 150.234 136.788 177.370 1.00 71.21  ? 387 PHE C CE1 1 
ATOM 2811 C CE2 . PHE A 1 387 ? 151.284 135.056 178.626 1.00 71.21  ? 387 PHE C CE2 1 
ATOM 2812 C CZ  . PHE A 1 387 ? 150.403 136.105 178.554 1.00 71.21  ? 387 PHE C CZ  1 
ATOM 2813 N N   . HIS A 1 388 ? 155.804 135.767 173.503 1.00 64.69  ? 388 HIS C N   1 
ATOM 2814 C CA  . HIS A 1 388 ? 156.731 135.188 172.551 1.00 64.69  ? 388 HIS C CA  1 
ATOM 2815 C C   . HIS A 1 388 ? 157.493 134.035 173.196 1.00 64.69  ? 388 HIS C C   1 
ATOM 2816 O O   . HIS A 1 388 ? 157.440 133.820 174.409 1.00 64.69  ? 388 HIS C O   1 
ATOM 2817 C CB  . HIS A 1 388 ? 157.709 136.245 172.051 1.00 64.69  ? 388 HIS C CB  1 
ATOM 2818 C CG  . HIS A 1 388 ? 157.089 137.592 171.861 1.00 64.69  ? 388 HIS C CG  1 
ATOM 2819 N ND1 . HIS A 1 388 ? 155.962 137.788 171.094 1.00 64.69  ? 388 HIS C ND1 1 
ATOM 2820 C CD2 . HIS A 1 388 ? 157.427 138.806 172.354 1.00 64.69  ? 388 HIS C CD2 1 
ATOM 2821 C CE1 . HIS A 1 388 ? 155.640 139.069 171.110 1.00 64.69  ? 388 HIS C CE1 1 
ATOM 2822 N NE2 . HIS A 1 388 ? 156.511 139.708 171.869 1.00 64.69  ? 388 HIS C NE2 1 
ATOM 2823 N N   . SER A 1 389 ? 158.205 133.285 172.363 1.00 63.33  ? 389 SER C N   1 
ATOM 2824 C CA  . SER A 1 389 ? 159.071 132.212 172.823 1.00 63.33  ? 389 SER C CA  1 
ATOM 2825 C C   . SER A 1 389 ? 160.376 132.259 172.041 1.00 63.33  ? 389 SER C C   1 
ATOM 2826 O O   . SER A 1 389 ? 160.430 132.744 170.908 1.00 63.33  ? 389 SER C O   1 
ATOM 2827 C CB  . SER A 1 389 ? 158.395 130.843 172.672 1.00 63.33  ? 389 SER C CB  1 
ATOM 2828 O OG  . SER A 1 389 ? 157.523 130.584 173.758 1.00 63.33  ? 389 SER C OG  1 
ATOM 2829 N N   . TYR A 1 390 ? 161.437 131.749 172.668 1.00 59.79  ? 390 TYR C N   1 
ATOM 2830 C CA  . TYR A 1 390 ? 162.765 131.722 172.066 1.00 59.79  ? 390 TYR C CA  1 
ATOM 2831 C C   . TYR A 1 390 ? 163.209 133.115 171.640 1.00 59.79  ? 390 TYR C C   1 
ATOM 2832 O O   . TYR A 1 390 ? 163.707 133.292 170.524 1.00 59.79  ? 390 TYR C O   1 
ATOM 2833 C CB  . TYR A 1 390 ? 162.800 130.779 170.859 1.00 59.79  ? 390 TYR C CB  1 
ATOM 2834 C CG  . TYR A 1 390 ? 162.409 129.350 171.161 1.00 59.79  ? 390 TYR C CG  1 
ATOM 2835 C CD1 . TYR A 1 390 ? 161.074 128.977 171.236 1.00 59.79  ? 390 TYR C CD1 1 
ATOM 2836 C CD2 . TYR A 1 390 ? 163.374 128.373 171.365 1.00 59.79  ? 390 TYR C CD2 1 
ATOM 2837 C CE1 . TYR A 1 390 ? 160.710 127.673 171.508 1.00 59.79  ? 390 TYR C CE1 1 
ATOM 2838 C CE2 . TYR A 1 390 ? 163.019 127.066 171.639 1.00 59.79  ? 390 TYR C CE2 1 
ATOM 2839 C CZ  . TYR A 1 390 ? 161.686 126.722 171.709 1.00 59.79  ? 390 TYR C CZ  1 
ATOM 2840 O OH  . TYR A 1 390 ? 161.325 125.423 171.981 1.00 59.79  ? 390 TYR C OH  1 
ATOM 2841 N N   . THR A 1 391 ? 163.036 134.110 172.506 1.00 53.79  ? 391 THR C N   1 
ATOM 2842 C CA  . THR A 1 391 ? 163.379 135.484 172.163 1.00 53.79  ? 391 THR C CA  1 
ATOM 2843 C C   . THR A 1 391 ? 163.926 136.182 173.404 1.00 53.79  ? 391 THR C C   1 
ATOM 2844 O O   . THR A 1 391 ? 164.042 135.587 174.480 1.00 53.79  ? 391 THR C O   1 
ATOM 2845 C CB  . THR A 1 391 ? 162.164 136.219 171.587 1.00 53.79  ? 391 THR C CB  1 
ATOM 2846 O OG1 . THR A 1 391 ? 162.586 137.459 171.007 1.00 53.79  ? 391 THR C OG1 1 
ATOM 2847 C CG2 . THR A 1 391 ? 161.164 136.506 172.682 1.00 53.79  ? 391 THR C CG2 1 
ATOM 2848 N N   . THR A 1 392 ? 164.258 137.463 173.248 1.00 49.59  ? 392 THR C N   1 
ATOM 2849 C CA  . THR A 1 392 ? 164.855 138.266 174.307 1.00 49.59  ? 392 THR C CA  1 
ATOM 2850 C C   . THR A 1 392 ? 164.166 139.620 174.349 1.00 49.59  ? 392 THR C C   1 
ATOM 2851 O O   . THR A 1 392 ? 163.845 140.185 173.299 1.00 49.59  ? 392 THR C O   1 
ATOM 2852 C CB  . THR A 1 392 ? 166.361 138.447 174.078 1.00 49.59  ? 392 THR C CB  1 
ATOM 2853 O OG1 . THR A 1 392 ? 166.994 137.165 174.026 1.00 49.59  ? 392 THR C OG1 1 
ATOM 2854 C CG2 . THR A 1 392 ? 166.987 139.264 175.195 1.00 49.59  ? 392 THR C CG2 1 
ATOM 2855 N N   . ILE A 1 393 ? 163.940 140.136 175.554 1.00 39.84  ? 393 ILE C N   1 
ATOM 2856 C CA  . ILE A 1 393 ? 163.309 141.433 175.756 1.00 39.84  ? 393 ILE C CA  1 
ATOM 2857 C C   . ILE A 1 393 ? 164.257 142.311 176.557 1.00 39.84  ? 393 ILE C C   1 
ATOM 2858 O O   . ILE A 1 393 ? 164.908 141.841 177.496 1.00 39.84  ? 393 ILE C O   1 
ATOM 2859 C CB  . ILE A 1 393 ? 161.954 141.313 176.481 1.00 39.84  ? 393 ILE C CB  1 
ATOM 2860 C CG1 . ILE A 1 393 ? 161.072 140.261 175.818 1.00 39.84  ? 393 ILE C CG1 1 
ATOM 2861 C CG2 . ILE A 1 393 ? 161.240 142.644 176.495 1.00 39.84  ? 393 ILE C CG2 1 
ATOM 2862 C CD1 . ILE A 1 393 ? 161.142 138.919 176.488 1.00 39.84  ? 393 ILE C CD1 1 
ATOM 2863 N N   . MET A 1 394 ? 164.331 143.584 176.190 1.00 40.31  ? 394 MET C N   1 
ATOM 2864 C CA  . MET A 1 394 ? 165.091 144.573 176.935 1.00 40.31  ? 394 MET C CA  1 
ATOM 2865 C C   . MET A 1 394 ? 164.146 145.595 177.553 1.00 40.31  ? 394 MET C C   1 
ATOM 2866 O O   . MET A 1 394 ? 162.943 145.613 177.280 1.00 40.31  ? 394 MET C O   1 
ATOM 2867 C CB  . MET A 1 394 ? 166.119 145.266 176.036 1.00 40.31  ? 394 MET C CB  1 
ATOM 2868 C CG  . MET A 1 394 ? 166.617 144.401 174.902 1.00 40.31  ? 394 MET C CG  1 
ATOM 2869 S SD  . MET A 1 394 ? 167.538 142.975 175.498 1.00 40.31  ? 394 MET C SD  1 
ATOM 2870 C CE  . MET A 1 394 ? 168.902 143.787 176.324 1.00 40.31  ? 394 MET C CE  1 
ATOM 2871 N N   . ALA A 1 395 ? 164.706 146.446 178.406 1.00 35.59  ? 395 ALA C N   1 
ATOM 2872 C CA  . ALA A 1 395 ? 163.946 147.511 179.044 1.00 35.59  ? 395 ALA C CA  1 
ATOM 2873 C C   . ALA A 1 395 ? 164.920 148.601 179.477 1.00 35.59  ? 395 ALA C C   1 
ATOM 2874 O O   . ALA A 1 395 ? 166.106 148.345 179.702 1.00 35.59  ? 395 ALA C O   1 
ATOM 2875 C CB  . ALA A 1 395 ? 163.122 146.966 180.215 1.00 35.59  ? 395 ALA C CB  1 
ATOM 2876 N N   . LEU A 1 396 ? 164.413 149.826 179.592 1.00 43.90  ? 396 LEU C N   1 
ATOM 2877 C CA  . LEU A 1 396 ? 165.231 150.970 179.972 1.00 43.90  ? 396 LEU C CA  1 
ATOM 2878 C C   . LEU A 1 396 ? 164.530 151.819 181.022 1.00 43.90  ? 396 LEU C C   1 
ATOM 2879 O O   . LEU A 1 396 ? 164.382 153.032 180.846 1.00 43.90  ? 396 LEU C O   1 
ATOM 2880 C CB  . LEU A 1 396 ? 165.578 151.819 178.751 1.00 43.90  ? 396 LEU C CB  1 
ATOM 2881 C CG  . LEU A 1 396 ? 167.057 152.182 178.651 1.00 43.90  ? 396 LEU C CG  1 
ATOM 2882 C CD1 . LEU A 1 396 ? 167.904 150.938 178.774 1.00 43.90  ? 396 LEU C CD1 1 
ATOM 2883 C CD2 . LEU A 1 396 ? 167.345 152.890 177.346 1.00 43.90  ? 396 LEU C CD2 1 
ATOM 2884 N N   . ILE A 1 397 ? 164.092 151.193 182.111 1.00 31.20  ? 397 ILE C N   1 
ATOM 2885 C CA  . ILE A 1 397 ? 163.256 151.856 183.103 1.00 31.20  ? 397 ILE C CA  1 
ATOM 2886 C C   . ILE A 1 397 ? 164.021 153.010 183.735 1.00 31.20  ? 397 ILE C C   1 
ATOM 2887 O O   . ILE A 1 397 ? 164.984 152.803 184.480 1.00 31.20  ? 397 ILE C O   1 
ATOM 2888 C CB  . ILE A 1 397 ? 162.787 150.858 184.174 1.00 31.20  ? 397 ILE C CB  1 
ATOM 2889 C CG1 . ILE A 1 397 ? 161.793 149.874 183.567 1.00 31.20  ? 397 ILE C CG1 1 
ATOM 2890 C CG2 . ILE A 1 397 ? 162.160 151.588 185.343 1.00 31.20  ? 397 ILE C CG2 1 
ATOM 2891 C CD1 . ILE A 1 397 ? 161.916 148.473 184.107 1.00 31.20  ? 397 ILE C CD1 1 
ATOM 2892 N N   . HIS A 1 398 ? 163.599 154.233 183.424 1.00 54.72  ? 398 HIS C N   1 
ATOM 2893 C CA  . HIS A 1 398 ? 164.222 155.438 183.953 1.00 54.72  ? 398 HIS C CA  1 
ATOM 2894 C C   . HIS A 1 398 ? 163.639 155.775 185.318 1.00 54.72  ? 398 HIS C C   1 
ATOM 2895 O O   . HIS A 1 398 ? 162.812 156.684 185.438 1.00 54.72  ? 398 HIS C O   1 
ATOM 2896 C CB  . HIS A 1 398 ? 164.024 156.600 182.978 1.00 54.72  ? 398 HIS C CB  1 
ATOM 2897 C CG  . HIS A 1 398 ? 164.791 157.835 183.334 1.00 54.72  ? 398 HIS C CG  1 
ATOM 2898 N ND1 . HIS A 1 398 ? 164.500 158.602 184.441 1.00 54.72  ? 398 HIS C ND1 1 
ATOM 2899 C CD2 . HIS A 1 398 ? 165.823 158.451 182.712 1.00 54.72  ? 398 HIS C CD2 1 
ATOM 2900 C CE1 . HIS A 1 398 ? 165.328 159.629 184.494 1.00 54.72  ? 398 HIS C CE1 1 
ATOM 2901 N NE2 . HIS A 1 398 ? 166.142 159.561 183.456 1.00 54.72  ? 398 HIS C NE2 1 
ATOM 2902 N N   . LEU A 1 399 ? 164.061 155.053 186.351 1.00 53.39  ? 399 LEU C N   1 
ATOM 2903 C CA  . LEU A 1 399 ? 163.535 155.250 187.699 1.00 53.39  ? 399 LEU C CA  1 
ATOM 2904 C C   . LEU A 1 399 ? 164.050 156.577 188.239 1.00 53.39  ? 399 LEU C C   1 
ATOM 2905 O O   . LEU A 1 399 ? 165.208 156.690 188.645 1.00 53.39  ? 399 LEU C O   1 
ATOM 2906 C CB  . LEU A 1 399 ? 163.943 154.090 188.601 1.00 53.39  ? 399 LEU C CB  1 
ATOM 2907 C CG  . LEU A 1 399 ? 163.005 153.697 189.746 1.00 53.39  ? 399 LEU C CG  1 
ATOM 2908 C CD1 . LEU A 1 399 ? 163.523 152.449 190.432 1.00 53.39  ? 399 LEU C CD1 1 
ATOM 2909 C CD2 . LEU A 1 399 ? 162.829 154.819 190.759 1.00 53.39  ? 399 LEU C CD2 1 
ATOM 2910 N N   . GLY A 1 400 ? 163.186 157.587 188.249 1.00 67.40  ? 400 GLY C N   1 
ATOM 2911 C CA  . GLY A 1 400 ? 163.552 158.890 188.767 1.00 67.40  ? 400 GLY C CA  1 
ATOM 2912 C C   . GLY A 1 400 ? 163.628 159.955 187.694 1.00 67.40  ? 400 GLY C C   1 
ATOM 2913 O O   . GLY A 1 400 ? 163.109 159.769 186.589 1.00 67.40  ? 400 GLY C O   1 
ATOM 2914 N N   . SER A 1 401 ? 164.275 161.073 188.006 1.00 83.84  ? 401 SER C N   1 
ATOM 2915 C CA  . SER A 1 401 ? 164.419 162.168 187.055 1.00 83.84  ? 401 SER C CA  1 
ATOM 2916 C C   . SER A 1 401 ? 165.581 163.079 187.437 1.00 83.84  ? 401 SER C C   1 
ATOM 2917 O O   . SER A 1 401 ? 165.607 164.254 187.072 1.00 83.84  ? 401 SER C O   1 
ATOM 2918 C CB  . SER A 1 401 ? 163.123 162.977 186.968 1.00 83.84  ? 401 SER C CB  1 
ATOM 2919 O OG  . SER A 1 401 ? 162.469 163.027 188.224 1.00 83.84  ? 401 SER C OG  1 
ATOM 2920 N N   . SER B 2 1   ? 140.052 182.722 198.814 1.00 132.53 ? 7   SER D N   1 
ATOM 2921 C CA  . SER B 2 1   ? 139.421 181.415 198.674 1.00 132.53 ? 7   SER D CA  1 
ATOM 2922 C C   . SER B 2 1   ? 139.477 180.926 197.232 1.00 132.53 ? 7   SER D C   1 
ATOM 2923 O O   . SER B 2 1   ? 138.469 180.488 196.678 1.00 132.53 ? 7   SER D O   1 
ATOM 2924 C CB  . SER B 2 1   ? 137.967 181.468 199.152 1.00 132.53 ? 7   SER D CB  1 
ATOM 2925 O OG  . SER B 2 1   ? 137.827 182.325 200.271 1.00 132.53 ? 7   SER D OG  1 
ATOM 2926 N N   . VAL B 2 2   ? 140.659 180.998 196.624 1.00 132.91 ? 8   VAL D N   1 
ATOM 2927 C CA  . VAL B 2 2   ? 140.823 180.576 195.238 1.00 132.91 ? 8   VAL D CA  1 
ATOM 2928 C C   . VAL B 2 2   ? 141.071 179.067 195.180 1.00 132.91 ? 8   VAL D C   1 
ATOM 2929 O O   . VAL B 2 2   ? 142.181 178.573 195.409 1.00 132.91 ? 8   VAL D O   1 
ATOM 2930 C CB  . VAL B 2 2   ? 141.898 181.433 194.526 1.00 132.91 ? 8   VAL D CB  1 
ATOM 2931 C CG1 . VAL B 2 2   ? 141.697 182.892 194.889 1.00 132.91 ? 8   VAL D CG1 1 
ATOM 2932 C CG2 . VAL B 2 2   ? 143.324 181.067 194.920 1.00 132.91 ? 8   VAL D CG2 1 
ATOM 2933 N N   . PHE B 2 3   ? 139.997 178.315 194.948 1.00 125.57 ? 9   PHE D N   1 
ATOM 2934 C CA  . PHE B 2 3   ? 140.089 176.865 194.835 1.00 125.57 ? 9   PHE D CA  1 
ATOM 2935 C C   . PHE B 2 3   ? 140.701 176.470 193.497 1.00 125.57 ? 9   PHE D C   1 
ATOM 2936 O O   . PHE B 2 3   ? 141.575 175.598 193.444 1.00 125.57 ? 9   PHE D O   1 
ATOM 2937 C CB  . PHE B 2 3   ? 138.704 176.237 195.032 1.00 125.57 ? 9   PHE D CB  1 
ATOM 2938 C CG  . PHE B 2 3   ? 138.477 174.967 194.254 1.00 125.57 ? 9   PHE D CG  1 
ATOM 2939 C CD1 . PHE B 2 3   ? 137.958 175.001 192.968 1.00 125.57 ? 9   PHE D CD1 1 
ATOM 2940 C CD2 . PHE B 2 3   ? 138.722 173.735 194.837 1.00 125.57 ? 9   PHE D CD2 1 
ATOM 2941 C CE1 . PHE B 2 3   ? 137.736 173.833 192.265 1.00 125.57 ? 9   PHE D CE1 1 
ATOM 2942 C CE2 . PHE B 2 3   ? 138.501 172.564 194.138 1.00 125.57 ? 9   PHE D CE2 1 
ATOM 2943 C CZ  . PHE B 2 3   ? 138.005 172.613 192.851 1.00 125.57 ? 9   PHE D CZ  1 
ATOM 2944 N N   . ALA B 2 4   ? 140.236 177.110 192.420 1.00 117.42 ? 10  ALA D N   1 
ATOM 2945 C CA  . ALA B 2 4   ? 140.685 176.866 191.052 1.00 117.42 ? 10  ALA D CA  1 
ATOM 2946 C C   . ALA B 2 4   ? 140.317 175.463 190.583 1.00 117.42 ? 10  ALA D C   1 
ATOM 2947 O O   . ALA B 2 4   ? 140.727 174.467 191.188 1.00 117.42 ? 10  ALA D O   1 
ATOM 2948 C CB  . ALA B 2 4   ? 142.193 177.098 190.919 1.00 117.42 ? 10  ALA D CB  1 
ATOM 2949 N N   . TYR B 2 5   ? 139.555 175.373 189.498 1.00 111.51 ? 11  TYR D N   1 
ATOM 2950 C CA  . TYR B 2 5   ? 139.161 174.097 188.928 1.00 111.51 ? 11  TYR D CA  1 
ATOM 2951 C C   . TYR B 2 5   ? 140.206 173.628 187.921 1.00 111.51 ? 11  TYR D C   1 
ATOM 2952 O O   . TYR B 2 5   ? 140.826 174.420 187.207 1.00 111.51 ? 11  TYR D O   1 
ATOM 2953 C CB  . TYR B 2 5   ? 137.778 174.205 188.281 1.00 111.51 ? 11  TYR D CB  1 
ATOM 2954 C CG  . TYR B 2 5   ? 136.996 172.912 188.266 1.00 111.51 ? 11  TYR D CG  1 
ATOM 2955 C CD1 . TYR B 2 5   ? 137.353 171.874 187.416 1.00 111.51 ? 11  TYR D CD1 1 
ATOM 2956 C CD2 . TYR B 2 5   ? 135.894 172.733 189.089 1.00 111.51 ? 11  TYR D CD2 1 
ATOM 2957 C CE1 . TYR B 2 5   ? 136.644 170.693 187.393 1.00 111.51 ? 11  TYR D CE1 1 
ATOM 2958 C CE2 . TYR B 2 5   ? 135.176 171.552 189.072 1.00 111.51 ? 11  TYR D CE2 1 
ATOM 2959 C CZ  . TYR B 2 5   ? 135.557 170.536 188.221 1.00 111.51 ? 11  TYR D CZ  1 
ATOM 2960 O OH  . TYR B 2 5   ? 134.850 169.358 188.197 1.00 111.51 ? 11  TYR D OH  1 
ATOM 2961 N N   . GLU B 2 6   ? 140.401 172.313 187.867 1.00 109.63 ? 12  GLU D N   1 
ATOM 2962 C CA  . GLU B 2 6   ? 141.298 171.710 186.892 1.00 109.63 ? 12  GLU D CA  1 
ATOM 2963 C C   . GLU B 2 6   ? 140.653 170.469 186.292 1.00 109.63 ? 12  GLU D C   1 
ATOM 2964 O O   . GLU B 2 6   ? 140.391 169.493 187.003 1.00 109.63 ? 12  GLU D O   1 
ATOM 2965 C CB  . GLU B 2 6   ? 142.642 171.362 187.536 1.00 109.63 ? 12  GLU D CB  1 
ATOM 2966 C CG  . GLU B 2 6   ? 143.599 172.540 187.711 1.00 109.63 ? 12  GLU D CG  1 
ATOM 2967 C CD  . GLU B 2 6   ? 144.072 173.137 186.394 1.00 109.63 ? 12  GLU D CD  1 
ATOM 2968 O OE1 . GLU B 2 6   ? 143.260 173.772 185.688 1.00 109.63 ? 12  GLU D OE1 1 
ATOM 2969 O OE2 . GLU B 2 6   ? 145.265 172.969 186.063 1.00 109.63 ? 12  GLU D OE2 1 
ATOM 2970 N N   . SER B 2 7   ? 140.392 170.497 184.989 1.00 96.77  ? 13  SER D N   1 
ATOM 2971 C CA  . SER B 2 7   ? 139.736 169.400 184.292 1.00 96.77  ? 13  SER D CA  1 
ATOM 2972 C C   . SER B 2 7   ? 140.735 168.718 183.372 1.00 96.77  ? 13  SER D C   1 
ATOM 2973 O O   . SER B 2 7   ? 141.365 169.374 182.536 1.00 96.77  ? 13  SER D O   1 
ATOM 2974 C CB  . SER B 2 7   ? 138.534 169.897 183.488 1.00 96.77  ? 13  SER D CB  1 
ATOM 2975 O OG  . SER B 2 7   ? 138.005 168.863 182.678 1.00 96.77  ? 13  SER D OG  1 
ATOM 2976 N N   . SER B 2 8   ? 140.875 167.405 183.527 1.00 90.72  ? 14  SER D N   1 
ATOM 2977 C CA  . SER B 2 8   ? 141.751 166.616 182.675 1.00 90.72  ? 14  SER D CA  1 
ATOM 2978 C C   . SER B 2 8   ? 141.058 166.119 181.415 1.00 90.72  ? 14  SER D C   1 
ATOM 2979 O O   . SER B 2 8   ? 141.680 165.399 180.627 1.00 90.72  ? 14  SER D O   1 
ATOM 2980 C CB  . SER B 2 8   ? 142.310 165.420 183.453 1.00 90.72  ? 14  SER D CB  1 
ATOM 2981 O OG  . SER B 2 8   ? 141.426 164.314 183.389 1.00 90.72  ? 14  SER D OG  1 
ATOM 2982 N N   . VAL B 2 9   ? 139.796 166.480 181.208 1.00 79.17  ? 15  VAL D N   1 
ATOM 2983 C CA  . VAL B 2 9   ? 139.022 166.008 180.071 1.00 79.17  ? 15  VAL D CA  1 
ATOM 2984 C C   . VAL B 2 9   ? 138.564 167.170 179.190 1.00 79.17  ? 15  VAL D C   1 
ATOM 2985 O O   . VAL B 2 9   ? 137.916 166.956 178.167 1.00 79.17  ? 15  VAL D O   1 
ATOM 2986 C CB  . VAL B 2 9   ? 137.833 165.148 180.535 1.00 79.17  ? 15  VAL D CB  1 
ATOM 2987 C CG1 . VAL B 2 9   ? 136.658 166.028 180.935 1.00 79.17  ? 15  VAL D CG1 1 
ATOM 2988 C CG2 . VAL B 2 9   ? 137.433 164.150 179.458 1.00 79.17  ? 15  VAL D CG2 1 
ATOM 2989 N N   . HIS B 2 10  ? 138.909 168.404 179.560 1.00 73.94  ? 16  HIS D N   1 
ATOM 2990 C CA  . HIS B 2 10  ? 138.464 169.574 178.816 1.00 73.94  ? 16  HIS D CA  1 
ATOM 2991 C C   . HIS B 2 10  ? 139.237 169.815 177.528 1.00 73.94  ? 16  HIS D C   1 
ATOM 2992 O O   . HIS B 2 10  ? 138.746 170.543 176.660 1.00 73.94  ? 16  HIS D O   1 
ATOM 2993 C CB  . HIS B 2 10  ? 138.556 170.833 179.682 1.00 73.94  ? 16  HIS D CB  1 
ATOM 2994 C CG  . HIS B 2 10  ? 137.900 172.025 179.064 1.00 73.94  ? 16  HIS D CG  1 
ATOM 2995 N ND1 . HIS B 2 10  ? 136.735 171.936 178.334 1.00 73.94  ? 16  HIS D ND1 1 
ATOM 2996 C CD2 . HIS B 2 10  ? 138.260 173.329 179.039 1.00 73.94  ? 16  HIS D CD2 1 
ATOM 2997 C CE1 . HIS B 2 10  ? 136.396 173.136 177.901 1.00 73.94  ? 16  HIS D CE1 1 
ATOM 2998 N NE2 . HIS B 2 10  ? 137.305 174.000 178.315 1.00 73.94  ? 16  HIS D NE2 1 
ATOM 2999 N N   . SER B 2 11  ? 140.420 169.226 177.372 1.00 59.37  ? 17  SER D N   1 
ATOM 3000 C CA  . SER B 2 11  ? 141.203 169.440 176.160 1.00 59.37  ? 17  SER D CA  1 
ATOM 3001 C C   . SER B 2 11  ? 140.908 168.365 175.117 1.00 59.37  ? 17  SER D C   1 
ATOM 3002 O O   . SER B 2 11  ? 140.746 168.666 173.929 1.00 59.37  ? 17  SER D O   1 
ATOM 3003 C CB  . SER B 2 11  ? 142.694 169.476 176.503 1.00 59.37  ? 17  SER D CB  1 
ATOM 3004 O OG  . SER B 2 11  ? 143.037 170.692 177.142 1.00 59.37  ? 17  SER D OG  1 
ATOM 3005 N N   . THR B 2 12  ? 140.830 167.108 175.555 1.00 59.10  ? 18  THR D N   1 
ATOM 3006 C CA  . THR B 2 12  ? 140.547 166.016 174.632 1.00 59.10  ? 18  THR D CA  1 
ATOM 3007 C C   . THR B 2 12  ? 139.174 166.182 173.995 1.00 59.10  ? 18  THR D C   1 
ATOM 3008 O O   . THR B 2 12  ? 139.008 165.985 172.786 1.00 59.10  ? 18  THR D O   1 
ATOM 3009 C CB  . THR B 2 12  ? 140.643 164.676 175.360 1.00 59.10  ? 18  THR D CB  1 
ATOM 3010 O OG1 . THR B 2 12  ? 141.926 164.562 175.987 1.00 59.10  ? 18  THR D OG1 1 
ATOM 3011 C CG2 . THR B 2 12  ? 140.462 163.528 174.382 1.00 59.10  ? 18  THR D CG2 1 
ATOM 3012 N N   . ASN B 2 13  ? 138.175 166.553 174.796 1.00 65.16  ? 19  ASN D N   1 
ATOM 3013 C CA  . ASN B 2 13  ? 136.837 166.756 174.254 1.00 65.16  ? 19  ASN D CA  1 
ATOM 3014 C C   . ASN B 2 13  ? 136.770 167.950 173.314 1.00 65.16  ? 19  ASN D C   1 
ATOM 3015 O O   . ASN B 2 13  ? 136.061 167.887 172.305 1.00 65.16  ? 19  ASN D O   1 
ATOM 3016 C CB  . ASN B 2 13  ? 135.827 166.928 175.384 1.00 65.16  ? 19  ASN D CB  1 
ATOM 3017 C CG  . ASN B 2 13  ? 135.663 165.672 176.210 1.00 65.16  ? 19  ASN D CG  1 
ATOM 3018 O OD1 . ASN B 2 13  ? 135.325 165.734 177.392 1.00 65.16  ? 19  ASN D OD1 1 
ATOM 3019 N ND2 . ASN B 2 13  ? 135.904 164.522 175.593 1.00 65.16  ? 19  ASN D ND2 1 
ATOM 3020 N N   . VAL B 2 14  ? 137.484 169.035 173.618 1.00 58.45  ? 20  VAL D N   1 
ATOM 3021 C CA  . VAL B 2 14  ? 137.505 170.168 172.702 1.00 58.45  ? 20  VAL D CA  1 
ATOM 3022 C C   . VAL B 2 14  ? 138.148 169.778 171.377 1.00 58.45  ? 20  VAL D C   1 
ATOM 3023 O O   . VAL B 2 14  ? 137.636 170.131 170.306 1.00 58.45  ? 20  VAL D O   1 
ATOM 3024 C CB  . VAL B 2 14  ? 138.217 171.369 173.347 1.00 58.45  ? 20  VAL D CB  1 
ATOM 3025 C CG1 . VAL B 2 14  ? 138.815 172.278 172.287 1.00 58.45  ? 20  VAL D CG1 1 
ATOM 3026 C CG2 . VAL B 2 14  ? 137.249 172.144 174.218 1.00 58.45  ? 20  VAL D CG2 1 
ATOM 3027 N N   . LEU B 2 15  ? 139.257 169.037 171.413 1.00 55.06  ? 21  LEU D N   1 
ATOM 3028 C CA  . LEU B 2 15  ? 139.896 168.618 170.171 1.00 55.06  ? 21  LEU D CA  1 
ATOM 3029 C C   . LEU B 2 15  ? 139.083 167.580 169.408 1.00 55.06  ? 21  LEU D C   1 
ATOM 3030 O O   . LEU B 2 15  ? 139.197 167.510 168.180 1.00 55.06  ? 21  LEU D O   1 
ATOM 3031 C CB  . LEU B 2 15  ? 141.300 168.079 170.443 1.00 55.06  ? 21  LEU D CB  1 
ATOM 3032 C CG  . LEU B 2 15  ? 142.441 169.094 170.342 1.00 55.06  ? 21  LEU D CG  1 
ATOM 3033 C CD1 . LEU B 2 15  ? 142.770 169.359 168.886 1.00 55.06  ? 21  LEU D CD1 1 
ATOM 3034 C CD2 . LEU B 2 15  ? 142.104 170.394 171.051 1.00 55.06  ? 21  LEU D CD2 1 
ATOM 3035 N N   . LEU B 2 16  ? 138.272 166.775 170.096 1.00 57.73  ? 22  LEU D N   1 
ATOM 3036 C CA  . LEU B 2 16  ? 137.353 165.882 169.399 1.00 57.73  ? 22  LEU D CA  1 
ATOM 3037 C C   . LEU B 2 16  ? 136.178 166.627 168.782 1.00 57.73  ? 22  LEU D C   1 
ATOM 3038 O O   . LEU B 2 16  ? 135.743 166.272 167.680 1.00 57.73  ? 22  LEU D O   1 
ATOM 3039 C CB  . LEU B 2 16  ? 136.836 164.797 170.346 1.00 57.73  ? 22  LEU D CB  1 
ATOM 3040 C CG  . LEU B 2 16  ? 137.627 163.488 170.452 1.00 57.73  ? 22  LEU D CG  1 
ATOM 3041 C CD1 . LEU B 2 16  ? 137.278 162.570 169.292 1.00 57.73  ? 22  LEU D CD1 1 
ATOM 3042 C CD2 . LEU B 2 16  ? 139.128 163.721 170.504 1.00 57.73  ? 22  LEU D CD2 1 
ATOM 3043 N N   . SER B 2 17  ? 135.658 167.648 169.462 1.00 58.97  ? 23  SER D N   1 
ATOM 3044 C CA  . SER B 2 17  ? 134.636 168.500 168.873 1.00 58.97  ? 23  SER D CA  1 
ATOM 3045 C C   . SER B 2 17  ? 135.151 169.259 167.660 1.00 58.97  ? 23  SER D C   1 
ATOM 3046 O O   . SER B 2 17  ? 134.406 169.424 166.689 1.00 58.97  ? 23  SER D O   1 
ATOM 3047 C CB  . SER B 2 17  ? 134.105 169.485 169.912 1.00 58.97  ? 23  SER D CB  1 
ATOM 3048 O OG  . SER B 2 17  ? 133.274 168.829 170.851 1.00 58.97  ? 23  SER D OG  1 
ATOM 3049 N N   . LEU B 2 18  ? 136.400 169.721 167.692 1.00 58.21  ? 24  LEU D N   1 
ATOM 3050 C CA  . LEU B 2 18  ? 137.006 170.308 166.505 1.00 58.21  ? 24  LEU D CA  1 
ATOM 3051 C C   . LEU B 2 18  ? 137.084 169.326 165.344 1.00 58.21  ? 24  LEU D C   1 
ATOM 3052 O O   . LEU B 2 18  ? 136.776 169.706 164.210 1.00 58.21  ? 24  LEU D O   1 
ATOM 3053 C CB  . LEU B 2 18  ? 138.404 170.838 166.827 1.00 58.21  ? 24  LEU D CB  1 
ATOM 3054 C CG  . LEU B 2 18  ? 138.451 171.993 167.825 1.00 58.21  ? 24  LEU D CG  1 
ATOM 3055 C CD1 . LEU B 2 18  ? 139.881 172.420 168.090 1.00 58.21  ? 24  LEU D CD1 1 
ATOM 3056 C CD2 . LEU B 2 18  ? 137.629 173.157 167.322 1.00 58.21  ? 24  LEU D CD2 1 
ATOM 3057 N N   . ASN B 2 19  ? 137.465 168.073 165.597 1.00 58.42  ? 25  ASN D N   1 
ATOM 3058 C CA  . ASN B 2 19  ? 137.425 167.040 164.572 1.00 58.42  ? 25  ASN D CA  1 
ATOM 3059 C C   . ASN B 2 19  ? 136.030 166.804 164.016 1.00 58.42  ? 25  ASN D C   1 
ATOM 3060 O O   . ASN B 2 19  ? 135.873 166.717 162.791 1.00 58.42  ? 25  ASN D O   1 
ATOM 3061 C CB  . ASN B 2 19  ? 137.953 165.714 165.128 1.00 58.42  ? 25  ASN D CB  1 
ATOM 3062 C CG  . ASN B 2 19  ? 138.588 164.851 164.062 1.00 58.42  ? 25  ASN D CG  1 
ATOM 3063 O OD1 . ASN B 2 19  ? 139.057 165.351 163.042 1.00 58.42  ? 25  ASN D OD1 1 
ATOM 3064 N ND2 . ASN B 2 19  ? 138.577 163.541 164.277 1.00 58.42  ? 25  ASN D ND2 1 
ATOM 3065 N N   . ASP B 2 20  ? 135.026 166.698 164.880 1.00 62.67  ? 26  ASP D N   1 
ATOM 3066 C CA  . ASP B 2 20  ? 133.649 166.523 164.441 1.00 62.67  ? 26  ASP D CA  1 
ATOM 3067 C C   . ASP B 2 20  ? 133.151 167.697 163.613 1.00 62.67  ? 26  ASP D C   1 
ATOM 3068 O O   . ASP B 2 20  ? 132.448 167.483 162.621 1.00 62.67  ? 26  ASP D O   1 
ATOM 3069 C CB  . ASP B 2 20  ? 132.728 166.316 165.646 1.00 62.67  ? 26  ASP D CB  1 
ATOM 3070 C CG  . ASP B 2 20  ? 131.263 166.357 165.268 1.00 62.67  ? 26  ASP D CG  1 
ATOM 3071 O OD1 . ASP B 2 20  ? 130.742 165.326 164.794 1.00 62.67  ? 26  ASP D OD1 1 
ATOM 3072 O OD2 . ASP B 2 20  ? 130.634 167.422 165.437 1.00 62.67  ? 26  ASP D OD2 1 
ATOM 3073 N N   . GLN B 2 21  ? 133.500 168.922 163.991 1.00 63.24  ? 27  GLN D N   1 
ATOM 3074 C CA  . GLN B 2 21  ? 133.206 170.093 163.182 1.00 63.24  ? 27  GLN D CA  1 
ATOM 3075 C C   . GLN B 2 21  ? 133.937 170.075 161.848 1.00 63.24  ? 27  GLN D C   1 
ATOM 3076 O O   . GLN B 2 21  ? 133.394 170.567 160.853 1.00 63.24  ? 27  GLN D O   1 
ATOM 3077 C CB  . GLN B 2 21  ? 133.575 171.365 163.949 1.00 63.24  ? 27  GLN D CB  1 
ATOM 3078 C CG  . GLN B 2 21  ? 132.694 171.636 165.151 1.00 63.24  ? 27  GLN D CG  1 
ATOM 3079 C CD  . GLN B 2 21  ? 132.490 173.112 165.397 1.00 63.24  ? 27  GLN D CD  1 
ATOM 3080 O OE1 . GLN B 2 21  ? 133.425 173.904 165.293 1.00 63.24  ? 27  GLN D OE1 1 
ATOM 3081 N NE2 . GLN B 2 21  ? 131.262 173.492 165.724 1.00 63.24  ? 27  GLN D NE2 1 
ATOM 3082 N N   . ARG B 2 22  ? 135.151 169.529 161.809 1.00 65.19  ? 28  ARG D N   1 
ATOM 3083 C CA  . ARG B 2 22  ? 135.896 169.395 160.565 1.00 65.19  ? 28  ARG D CA  1 
ATOM 3084 C C   . ARG B 2 22  ? 135.219 168.423 159.609 1.00 65.19  ? 28  ARG D C   1 
ATOM 3085 O O   . ARG B 2 22  ? 135.087 168.712 158.415 1.00 65.19  ? 28  ARG D O   1 
ATOM 3086 C CB  . ARG B 2 22  ? 137.323 168.920 160.841 1.00 65.19  ? 28  ARG D CB  1 
ATOM 3087 C CG  . ARG B 2 22  ? 138.279 169.147 159.686 1.00 65.19  ? 28  ARG D CG  1 
ATOM 3088 C CD  . ARG B 2 22  ? 139.585 168.402 159.899 1.00 65.19  ? 28  ARG D CD  1 
ATOM 3089 N NE  . ARG B 2 22  ? 139.642 167.186 159.097 1.00 65.19  ? 28  ARG D NE  1 
ATOM 3090 C CZ  . ARG B 2 22  ? 139.679 165.958 159.597 1.00 65.19  ? 28  ARG D CZ  1 
ATOM 3091 N NH1 . ARG B 2 22  ? 139.671 165.743 160.901 1.00 65.19  ? 28  ARG D NH1 1 
ATOM 3092 N NH2 . ARG B 2 22  ? 139.723 164.921 158.767 1.00 65.19  ? 28  ARG D NH2 1 
ATOM 3093 N N   . LYS B 2 23  ? 134.796 167.268 160.122 1.00 64.40  ? 29  LYS D N   1 
ATOM 3094 C CA  . LYS B 2 23  ? 134.292 166.200 159.264 1.00 64.40  ? 29  LYS D CA  1 
ATOM 3095 C C   . LYS B 2 23  ? 133.067 166.615 158.459 1.00 64.40  ? 29  LYS D C   1 
ATOM 3096 O O   . LYS B 2 23  ? 133.008 166.372 157.250 1.00 64.40  ? 29  LYS D O   1 
ATOM 3097 C CB  . LYS B 2 23  ? 133.967 164.954 160.089 1.00 64.40  ? 29  LYS D CB  1 
ATOM 3098 C CG  . LYS B 2 23  ? 135.173 164.084 160.392 1.00 64.40  ? 29  LYS D CG  1 
ATOM 3099 C CD  . LYS B 2 23  ? 134.777 162.852 161.185 1.00 64.40  ? 29  LYS D CD  1 
ATOM 3100 C CE  . LYS B 2 23  ? 135.991 162.176 161.797 1.00 64.40  ? 29  LYS D CE  1 
ATOM 3101 N NZ  . LYS B 2 23  ? 135.606 161.026 162.658 1.00 64.40  ? 29  LYS D NZ  1 
ATOM 3102 N N   . LYS B 2 24  ? 132.084 167.240 159.107 1.00 68.99  ? 30  LYS D N   1 
ATOM 3103 C CA  . LYS B 2 24  ? 130.837 167.604 158.433 1.00 68.99  ? 30  LYS D CA  1 
ATOM 3104 C C   . LYS B 2 24  ? 130.802 169.100 158.110 1.00 68.99  ? 30  LYS D C   1 
ATOM 3105 O O   . LYS B 2 24  ? 129.747 169.725 158.005 1.00 68.99  ? 30  LYS D O   1 
ATOM 3106 C CB  . LYS B 2 24  ? 129.641 167.180 159.276 1.00 68.99  ? 30  LYS D CB  1 
ATOM 3107 C CG  . LYS B 2 24  ? 129.834 167.351 160.769 1.00 68.99  ? 30  LYS D CG  1 
ATOM 3108 C CD  . LYS B 2 24  ? 128.788 166.574 161.552 1.00 68.99  ? 30  LYS D CD  1 
ATOM 3109 C CE  . LYS B 2 24  ? 127.394 167.132 161.330 1.00 68.99  ? 30  LYS D CE  1 
ATOM 3110 N NZ  . LYS B 2 24  ? 127.279 168.538 161.802 1.00 68.99  ? 30  LYS D NZ  1 
ATOM 3111 N N   . ASP B 2 25  ? 132.000 169.665 157.940 1.00 70.09  ? 31  ASP D N   1 
ATOM 3112 C CA  . ASP B 2 25  ? 132.183 171.040 157.482 1.00 70.09  ? 31  ASP D CA  1 
ATOM 3113 C C   . ASP B 2 25  ? 131.382 172.040 158.304 1.00 70.09  ? 31  ASP D C   1 
ATOM 3114 O O   . ASP B 2 25  ? 130.620 172.838 157.749 1.00 70.09  ? 31  ASP D O   1 
ATOM 3115 C CB  . ASP B 2 25  ? 131.799 171.158 156.007 1.00 70.09  ? 31  ASP D CB  1 
ATOM 3116 C CG  . ASP B 2 25  ? 132.584 170.215 155.125 1.00 70.09  ? 31  ASP D CG  1 
ATOM 3117 O OD1 . ASP B 2 25  ? 132.964 169.129 155.611 1.00 70.09  ? 31  ASP D OD1 1 
ATOM 3118 O OD2 . ASP B 2 25  ? 132.818 170.555 153.947 1.00 70.09  ? 31  ASP D OD2 1 
ATOM 3119 N N   . VAL B 2 26  ? 131.544 172.010 159.619 1.00 71.50  ? 32  VAL D N   1 
ATOM 3120 C CA  . VAL B 2 26  ? 130.813 172.891 160.519 1.00 71.50  ? 32  VAL D CA  1 
ATOM 3121 C C   . VAL B 2 26  ? 131.752 174.038 160.871 1.00 71.50  ? 32  VAL D C   1 
ATOM 3122 O O   . VAL B 2 26  ? 132.662 173.881 161.694 1.00 71.50  ? 32  VAL D O   1 
ATOM 3123 C CB  . VAL B 2 26  ? 130.321 172.141 161.765 1.00 71.50  ? 32  VAL D CB  1 
ATOM 3124 C CG1 . VAL B 2 26  ? 129.471 173.037 162.641 1.00 71.50  ? 32  VAL D CG1 1 
ATOM 3125 C CG2 . VAL B 2 26  ? 129.544 170.902 161.358 1.00 71.50  ? 32  VAL D CG2 1 
ATOM 3126 N N   . LEU B 2 27  ? 131.534 175.190 160.239 1.00 74.46  ? 33  LEU D N   1 
ATOM 3127 C CA  . LEU B 2 27  ? 132.391 176.372 160.297 1.00 74.46  ? 33  LEU D CA  1 
ATOM 3128 C C   . LEU B 2 27  ? 133.841 176.089 159.926 1.00 74.46  ? 33  LEU D C   1 
ATOM 3129 O O   . LEU B 2 27  ? 134.749 176.526 160.639 1.00 74.46  ? 33  LEU D O   1 
ATOM 3130 C CB  . LEU B 2 27  ? 132.355 177.074 161.663 1.00 74.46  ? 33  LEU D CB  1 
ATOM 3131 C CG  . LEU B 2 27  ? 131.064 177.258 162.457 1.00 74.46  ? 33  LEU D CG  1 
ATOM 3132 C CD1 . LEU B 2 27  ? 130.806 176.092 163.373 1.00 74.46  ? 33  LEU D CD1 1 
ATOM 3133 C CD2 . LEU B 2 27  ? 131.130 178.549 163.241 1.00 74.46  ? 33  LEU D CD2 1 
ATOM 3134 N N   . CYS B 2 28  ? 134.091 175.348 158.850 1.00 84.79  ? 34  CYS D N   1 
ATOM 3135 C CA  . CYS B 2 28  ? 135.434 175.303 158.288 1.00 84.79  ? 34  CYS D CA  1 
ATOM 3136 C C   . CYS B 2 28  ? 135.676 176.552 157.449 1.00 84.79  ? 34  CYS D C   1 
ATOM 3137 O O   . CYS B 2 28  ? 134.927 176.833 156.510 1.00 84.79  ? 34  CYS D O   1 
ATOM 3138 C CB  . CYS B 2 28  ? 135.615 174.047 157.438 1.00 84.79  ? 34  CYS D CB  1 
ATOM 3139 S SG  . CYS B 2 28  ? 135.559 172.498 158.367 1.00 84.79  ? 34  CYS D SG  1 
ATOM 3140 N N   . ASP B 2 29  ? 136.725 177.308 157.788 1.00 82.83  ? 35  ASP D N   1 
ATOM 3141 C CA  . ASP B 2 29  ? 136.982 178.574 157.113 1.00 82.83  ? 35  ASP D CA  1 
ATOM 3142 C C   . ASP B 2 29  ? 138.277 178.580 156.311 1.00 82.83  ? 35  ASP D C   1 
ATOM 3143 O O   . ASP B 2 29  ? 138.707 179.652 155.871 1.00 82.83  ? 35  ASP D O   1 
ATOM 3144 C CB  . ASP B 2 29  ? 137.000 179.734 158.116 1.00 82.83  ? 35  ASP D CB  1 
ATOM 3145 C CG  . ASP B 2 29  ? 135.959 179.583 159.206 1.00 82.83  ? 35  ASP D CG  1 
ATOM 3146 O OD1 . ASP B 2 29  ? 136.101 178.666 160.035 1.00 82.83  ? 35  ASP D OD1 1 
ATOM 3147 O OD2 . ASP B 2 29  ? 134.994 180.377 159.227 1.00 82.83  ? 35  ASP D OD2 1 
ATOM 3148 N N   . VAL B 2 30  ? 138.913 177.429 156.108 1.00 81.33  ? 36  VAL D N   1 
ATOM 3149 C CA  . VAL B 2 30  ? 140.125 177.352 155.303 1.00 81.33  ? 36  VAL D CA  1 
ATOM 3150 C C   . VAL B 2 30  ? 140.074 176.099 154.439 1.00 81.33  ? 36  VAL D C   1 
ATOM 3151 O O   . VAL B 2 30  ? 139.642 175.029 154.879 1.00 81.33  ? 36  VAL D O   1 
ATOM 3152 C CB  . VAL B 2 30  ? 141.400 177.382 156.179 1.00 81.33  ? 36  VAL D CB  1 
ATOM 3153 C CG1 . VAL B 2 30  ? 141.465 176.173 157.097 1.00 81.33  ? 36  VAL D CG1 1 
ATOM 3154 C CG2 . VAL B 2 30  ? 142.645 177.473 155.310 1.00 81.33  ? 36  VAL D CG2 1 
ATOM 3155 N N   . THR B 2 31  ? 140.490 176.252 153.184 1.00 81.43  ? 37  THR D N   1 
ATOM 3156 C CA  . THR B 2 31  ? 140.608 175.144 152.249 1.00 81.43  ? 37  THR D CA  1 
ATOM 3157 C C   . THR B 2 31  ? 142.056 175.050 151.796 1.00 81.43  ? 37  THR D C   1 
ATOM 3158 O O   . THR B 2 31  ? 142.670 176.061 151.444 1.00 81.43  ? 37  THR D O   1 
ATOM 3159 C CB  . THR B 2 31  ? 139.683 175.327 151.040 1.00 81.43  ? 37  THR D CB  1 
ATOM 3160 O OG1 . THR B 2 31  ? 138.366 175.665 151.494 1.00 81.43  ? 37  THR D OG1 1 
ATOM 3161 C CG2 . THR B 2 31  ? 139.611 174.048 150.227 1.00 81.43  ? 37  THR D CG2 1 
ATOM 3162 N N   . ILE B 2 32  ? 142.604 173.839 151.819 1.00 75.86  ? 38  ILE D N   1 
ATOM 3163 C CA  . ILE B 2 32  ? 144.007 173.598 151.495 1.00 75.86  ? 38  ILE D CA  1 
ATOM 3164 C C   . ILE B 2 32  ? 144.052 172.547 150.392 1.00 75.86  ? 38  ILE D C   1 
ATOM 3165 O O   . ILE B 2 32  ? 143.258 171.599 150.390 1.00 75.86  ? 38  ILE D O   1 
ATOM 3166 C CB  . ILE B 2 32  ? 144.824 173.165 152.717 1.00 75.86  ? 38  ILE D CB  1 
ATOM 3167 C CG1 . ILE B 2 32  ? 144.384 171.786 153.204 1.00 75.86  ? 38  ILE D CG1 1 
ATOM 3168 C CG2 . ILE B 2 32  ? 144.699 174.183 153.837 1.00 75.86  ? 38  ILE D CG2 1 
ATOM 3169 C CD1 . ILE B 2 32  ? 145.460 171.034 153.913 1.00 75.86  ? 38  ILE D CD1 1 
ATOM 3170 N N   . PHE B 2 33  ? 144.944 172.738 149.425 1.00 73.57  ? 39  PHE D N   1 
ATOM 3171 C CA  . PHE B 2 33  ? 145.126 171.771 148.358 1.00 73.57  ? 39  PHE D CA  1 
ATOM 3172 C C   . PHE B 2 33  ? 146.468 171.059 148.502 1.00 73.57  ? 39  PHE D C   1 
ATOM 3173 O O   . PHE B 2 33  ? 147.514 171.674 148.719 1.00 73.57  ? 39  PHE D O   1 
ATOM 3174 C CB  . PHE B 2 33  ? 145.045 172.448 146.992 1.00 73.57  ? 39  PHE D CB  1 
ATOM 3175 C CG  . PHE B 2 33  ? 143.781 173.224 146.768 1.00 73.57  ? 39  PHE D CG  1 
ATOM 3176 C CD1 . PHE B 2 33  ? 142.564 172.578 146.661 1.00 73.57  ? 39  PHE D CD1 1 
ATOM 3177 C CD2 . PHE B 2 33  ? 143.814 174.603 146.652 1.00 73.57  ? 39  PHE D CD2 1 
ATOM 3178 C CE1 . PHE B 2 33  ? 141.403 173.294 146.446 1.00 73.57  ? 39  PHE D CE1 1 
ATOM 3179 C CE2 . PHE B 2 33  ? 142.657 175.324 146.440 1.00 73.57  ? 39  PHE D CE2 1 
ATOM 3180 C CZ  . PHE B 2 33  ? 141.450 174.668 146.337 1.00 73.57  ? 39  PHE D CZ  1 
ATOM 3181 N N   . VAL B 2 34  ? 146.425 169.736 148.376 1.00 72.26  ? 40  VAL D N   1 
ATOM 3182 C CA  . VAL B 2 34  ? 147.630 168.923 148.268 1.00 72.26  ? 40  VAL D CA  1 
ATOM 3183 C C   . VAL B 2 34  ? 147.459 168.068 147.023 1.00 72.26  ? 40  VAL D C   1 
ATOM 3184 O O   . VAL B 2 34  ? 146.529 167.257 146.949 1.00 72.26  ? 40  VAL D O   1 
ATOM 3185 C CB  . VAL B 2 34  ? 147.854 168.064 149.526 1.00 72.26  ? 40  VAL D CB  1 
ATOM 3186 C CG1 . VAL B 2 34  ? 148.681 166.834 149.194 1.00 72.26  ? 40  VAL D CG1 1 
ATOM 3187 C CG2 . VAL B 2 34  ? 148.520 168.886 150.615 1.00 72.26  ? 40  VAL D CG2 1 
ATOM 3188 N N   . GLU B 2 35  ? 148.344 168.245 146.040 1.00 76.28  ? 41  GLU D N   1 
ATOM 3189 C CA  . GLU B 2 35  ? 148.097 167.740 144.693 1.00 76.28  ? 41  GLU D CA  1 
ATOM 3190 C C   . GLU B 2 35  ? 146.700 168.183 144.285 1.00 76.28  ? 41  GLU D C   1 
ATOM 3191 O O   . GLU B 2 35  ? 146.408 169.383 144.291 1.00 76.28  ? 41  GLU D O   1 
ATOM 3192 C CB  . GLU B 2 35  ? 148.242 166.219 144.635 1.00 76.28  ? 41  GLU D CB  1 
ATOM 3193 C CG  . GLU B 2 35  ? 149.515 165.695 145.275 1.00 76.28  ? 41  GLU D CG  1 
ATOM 3194 C CD  . GLU B 2 35  ? 149.946 164.365 144.695 1.00 76.28  ? 41  GLU D CD  1 
ATOM 3195 O OE1 . GLU B 2 35  ? 151.162 164.170 144.487 1.00 76.28  ? 41  GLU D OE1 1 
ATOM 3196 O OE2 . GLU B 2 35  ? 149.067 163.514 144.445 1.00 76.28  ? 41  GLU D OE2 1 
ATOM 3197 N N   . GLY B 2 36  ? 145.824 167.244 143.937 1.00 72.92  ? 42  GLY D N   1 
ATOM 3198 C CA  . GLY B 2 36  ? 144.418 167.551 144.089 1.00 72.92  ? 42  GLY D CA  1 
ATOM 3199 C C   . GLY B 2 36  ? 143.649 166.490 144.847 1.00 72.92  ? 42  GLY D C   1 
ATOM 3200 O O   . GLY B 2 36  ? 143.266 165.459 144.288 1.00 72.92  ? 42  GLY D O   1 
ATOM 3201 N N   . GLN B 2 37  ? 143.387 166.773 146.123 1.00 76.18  ? 43  GLN D N   1 
ATOM 3202 C CA  . GLN B 2 37  ? 142.381 166.124 146.956 1.00 76.18  ? 43  GLN D CA  1 
ATOM 3203 C C   . GLN B 2 37  ? 142.007 167.141 148.023 1.00 76.18  ? 43  GLN D C   1 
ATOM 3204 O O   . GLN B 2 37  ? 142.758 167.321 148.984 1.00 76.18  ? 43  GLN D O   1 
ATOM 3205 C CB  . GLN B 2 37  ? 142.844 164.825 147.646 1.00 76.18  ? 43  GLN D CB  1 
ATOM 3206 C CG  . GLN B 2 37  ? 143.382 163.655 146.806 1.00 76.18  ? 43  GLN D CG  1 
ATOM 3207 C CD  . GLN B 2 37  ? 144.788 163.849 146.262 1.00 76.18  ? 43  GLN D CD  1 
ATOM 3208 O OE1 . GLN B 2 37  ? 145.361 164.931 146.334 1.00 76.18  ? 43  GLN D OE1 1 
ATOM 3209 N NE2 . GLN B 2 37  ? 145.350 162.782 145.706 1.00 76.18  ? 43  GLN D NE2 1 
ATOM 3210 N N   . ARG B 2 38  ? 140.879 167.823 147.863 1.00 80.77  ? 44  ARG D N   1 
ATOM 3211 C CA  . ARG B 2 38  ? 140.549 168.951 148.724 1.00 80.77  ? 44  ARG D CA  1 
ATOM 3212 C C   . ARG B 2 38  ? 140.423 168.535 150.183 1.00 80.77  ? 44  ARG D C   1 
ATOM 3213 O O   . ARG B 2 38  ? 139.741 167.559 150.508 1.00 80.77  ? 44  ARG D O   1 
ATOM 3214 C CB  . ARG B 2 38  ? 139.247 169.596 148.249 1.00 80.77  ? 44  ARG D CB  1 
ATOM 3215 C CG  . ARG B 2 38  ? 139.327 171.106 148.116 1.00 80.77  ? 44  ARG D CG  1 
ATOM 3216 C CD  . ARG B 2 38  ? 138.004 171.764 147.718 1.00 80.77  ? 44  ARG D CD  1 
ATOM 3217 N NE  . ARG B 2 38  ? 136.874 171.371 148.555 1.00 80.77  ? 44  ARG D NE  1 
ATOM 3218 C CZ  . ARG B 2 38  ? 136.063 170.351 148.305 1.00 80.77  ? 44  ARG D CZ  1 
ATOM 3219 N NH1 . ARG B 2 38  ? 136.195 169.612 147.216 1.00 80.77  ? 44  ARG D NH1 1 
ATOM 3220 N NH2 . ARG B 2 38  ? 135.088 170.073 149.165 1.00 80.77  ? 44  ARG D NH2 1 
ATOM 3221 N N   . PHE B 2 39  ? 141.087 169.282 151.062 1.00 72.29  ? 45  PHE D N   1 
ATOM 3222 C CA  . PHE B 2 39  ? 140.951 169.118 152.502 1.00 72.29  ? 45  PHE D CA  1 
ATOM 3223 C C   . PHE B 2 39  ? 140.360 170.377 153.127 1.00 72.29  ? 45  PHE D C   1 
ATOM 3224 O O   . PHE B 2 39  ? 140.538 171.492 152.631 1.00 72.29  ? 45  PHE D O   1 
ATOM 3225 C CB  . PHE B 2 39  ? 142.297 168.809 153.159 1.00 72.29  ? 45  PHE D CB  1 
ATOM 3226 C CG  . PHE B 2 39  ? 142.760 167.397 152.969 1.00 72.29  ? 45  PHE D CG  1 
ATOM 3227 C CD1 . PHE B 2 39  ? 143.465 167.032 151.841 1.00 72.29  ? 45  PHE D CD1 1 
ATOM 3228 C CD2 . PHE B 2 39  ? 142.490 166.434 153.924 1.00 72.29  ? 45  PHE D CD2 1 
ATOM 3229 C CE1 . PHE B 2 39  ? 143.891 165.735 151.663 1.00 72.29  ? 45  PHE D CE1 1 
ATOM 3230 C CE2 . PHE B 2 39  ? 142.914 165.135 153.753 1.00 72.29  ? 45  PHE D CE2 1 
ATOM 3231 C CZ  . PHE B 2 39  ? 143.616 164.785 152.621 1.00 72.29  ? 45  PHE D CZ  1 
ATOM 3232 N N   . ARG B 2 40  ? 139.656 170.184 154.238 1.00 78.64  ? 46  ARG D N   1 
ATOM 3233 C CA  . ARG B 2 40  ? 139.052 171.278 154.980 1.00 78.64  ? 46  ARG D CA  1 
ATOM 3234 C C   . ARG B 2 40  ? 139.516 171.218 156.427 1.00 78.64  ? 46  ARG D C   1 
ATOM 3235 O O   . ARG B 2 40  ? 139.672 170.136 156.999 1.00 78.64  ? 46  ARG D O   1 
ATOM 3236 C CB  . ARG B 2 40  ? 137.522 171.221 154.918 1.00 78.64  ? 46  ARG D CB  1 
ATOM 3237 C CG  . ARG B 2 40  ? 136.935 171.811 153.650 1.00 78.64  ? 46  ARG D CG  1 
ATOM 3238 C CD  . ARG B 2 40  ? 136.772 173.315 153.760 1.00 78.64  ? 46  ARG D CD  1 
ATOM 3239 N NE  . ARG B 2 40  ? 135.370 173.706 153.835 1.00 78.64  ? 46  ARG D NE  1 
ATOM 3240 C CZ  . ARG B 2 40  ? 134.946 174.960 153.899 1.00 78.64  ? 46  ARG D CZ  1 
ATOM 3241 N NH1 . ARG B 2 40  ? 135.793 175.976 153.894 1.00 78.64  ? 46  ARG D NH1 1 
ATOM 3242 N NH2 . ARG B 2 40  ? 133.640 175.201 153.968 1.00 78.64  ? 46  ARG D NH2 1 
ATOM 3243 N N   . ALA B 2 41  ? 139.739 172.389 157.014 1.00 74.58  ? 47  ALA D N   1 
ATOM 3244 C CA  . ALA B 2 41  ? 140.235 172.477 158.381 1.00 74.58  ? 47  ALA D CA  1 
ATOM 3245 C C   . ALA B 2 41  ? 139.795 173.810 158.975 1.00 74.58  ? 47  ALA D C   1 
ATOM 3246 O O   . ALA B 2 41  ? 138.966 174.523 158.401 1.00 74.58  ? 47  ALA D O   1 
ATOM 3247 C CB  . ALA B 2 41  ? 141.758 172.305 158.413 1.00 74.58  ? 47  ALA D CB  1 
ATOM 3248 N N   . HIS B 2 42  ? 140.351 174.143 160.136 1.00 67.03  ? 48  HIS D N   1 
ATOM 3249 C CA  . HIS B 2 42  ? 140.076 175.399 160.822 1.00 67.03  ? 48  HIS D CA  1 
ATOM 3250 C C   . HIS B 2 42  ? 141.313 176.280 160.749 1.00 67.03  ? 48  HIS D C   1 
ATOM 3251 O O   . HIS B 2 42  ? 142.439 175.785 160.868 1.00 67.03  ? 48  HIS D O   1 
ATOM 3252 C CB  . HIS B 2 42  ? 139.679 175.158 162.277 1.00 67.03  ? 48  HIS D CB  1 
ATOM 3253 C CG  . HIS B 2 42  ? 138.419 174.370 162.436 1.00 67.03  ? 48  HIS D CG  1 
ATOM 3254 N ND1 . HIS B 2 42  ? 138.413 173.044 162.809 1.00 67.03  ? 48  HIS D ND1 1 
ATOM 3255 C CD2 . HIS B 2 42  ? 137.122 174.723 162.281 1.00 67.03  ? 48  HIS D CD2 1 
ATOM 3256 C CE1 . HIS B 2 42  ? 137.166 172.613 162.871 1.00 67.03  ? 48  HIS D CE1 1 
ATOM 3257 N NE2 . HIS B 2 42  ? 136.363 173.613 162.555 1.00 67.03  ? 48  HIS D NE2 1 
ATOM 3258 N N   . ARG B 2 43  ? 141.101 177.581 160.545 1.00 69.91  ? 49  ARG D N   1 
ATOM 3259 C CA  . ARG B 2 43  ? 142.220 178.512 160.484 1.00 69.91  ? 49  ARG D CA  1 
ATOM 3260 C C   . ARG B 2 43  ? 142.964 178.582 161.810 1.00 69.91  ? 49  ARG D C   1 
ATOM 3261 O O   . ARG B 2 43  ? 144.199 178.538 161.836 1.00 69.91  ? 49  ARG D O   1 
ATOM 3262 C CB  . ARG B 2 43  ? 141.713 179.898 160.085 1.00 69.91  ? 49  ARG D CB  1 
ATOM 3263 C CG  . ARG B 2 43  ? 142.744 180.771 159.400 1.00 69.91  ? 49  ARG D CG  1 
ATOM 3264 C CD  . ARG B 2 43  ? 142.185 182.151 159.089 1.00 69.91  ? 49  ARG D CD  1 
ATOM 3265 N NE  . ARG B 2 43  ? 141.628 182.233 157.745 1.00 69.91  ? 49  ARG D NE  1 
ATOM 3266 C CZ  . ARG B 2 43  ? 140.334 182.161 157.467 1.00 69.91  ? 49  ARG D CZ  1 
ATOM 3267 N NH1 . ARG B 2 43  ? 139.431 182.007 158.420 1.00 69.91  ? 49  ARG D NH1 1 
ATOM 3268 N NH2 . ARG B 2 43  ? 139.936 182.247 156.201 1.00 69.91  ? 49  ARG D NH2 1 
ATOM 3269 N N   . SER B 2 44  ? 142.231 178.669 162.921 1.00 66.19  ? 50  SER D N   1 
ATOM 3270 C CA  . SER B 2 44  ? 142.858 178.813 164.231 1.00 66.19  ? 50  SER D CA  1 
ATOM 3271 C C   . SER B 2 44  ? 143.644 177.570 164.629 1.00 66.19  ? 50  SER D C   1 
ATOM 3272 O O   . SER B 2 44  ? 144.728 177.682 165.211 1.00 66.19  ? 50  SER D O   1 
ATOM 3273 C CB  . SER B 2 44  ? 141.798 179.124 165.286 1.00 66.19  ? 50  SER D CB  1 
ATOM 3274 O OG  . SER B 2 44  ? 141.233 177.934 165.805 1.00 66.19  ? 50  SER D OG  1 
ATOM 3275 N N   . VAL B 2 45  ? 143.113 176.381 164.336 1.00 61.77  ? 51  VAL D N   1 
ATOM 3276 C CA  . VAL B 2 45  ? 143.784 175.149 164.739 1.00 61.77  ? 51  VAL D CA  1 
ATOM 3277 C C   . VAL B 2 45  ? 145.138 175.028 164.054 1.00 61.77  ? 51  VAL D C   1 
ATOM 3278 O O   . VAL B 2 45  ? 146.157 174.766 164.705 1.00 61.77  ? 51  VAL D O   1 
ATOM 3279 C CB  . VAL B 2 45  ? 142.891 173.933 164.439 1.00 61.77  ? 51  VAL D CB  1 
ATOM 3280 C CG1 . VAL B 2 45  ? 143.665 172.647 164.644 1.00 61.77  ? 51  VAL D CG1 1 
ATOM 3281 C CG2 . VAL B 2 45  ? 141.653 173.959 165.313 1.00 61.77  ? 51  VAL D CG2 1 
ATOM 3282 N N   . LEU B 2 46  ? 145.178 175.229 162.740 1.00 66.41  ? 52  LEU D N   1 
ATOM 3283 C CA  . LEU B 2 46  ? 146.426 175.156 161.998 1.00 66.41  ? 52  LEU D CA  1 
ATOM 3284 C C   . LEU B 2 46  ? 147.320 176.365 162.222 1.00 66.41  ? 52  LEU D C   1 
ATOM 3285 O O   . LEU B 2 46  ? 148.522 176.284 161.949 1.00 66.41  ? 52  LEU D O   1 
ATOM 3286 C CB  . LEU B 2 46  ? 146.147 175.001 160.501 1.00 66.41  ? 52  LEU D CB  1 
ATOM 3287 C CG  . LEU B 2 46  ? 145.646 173.621 160.073 1.00 66.41  ? 52  LEU D CG  1 
ATOM 3288 C CD1 . LEU B 2 46  ? 145.137 173.660 158.645 1.00 66.41  ? 52  LEU D CD1 1 
ATOM 3289 C CD2 . LEU B 2 46  ? 146.740 172.579 160.229 1.00 66.41  ? 52  LEU D CD2 1 
ATOM 3290 N N   . ALA B 2 47  ? 146.776 177.472 162.718 1.00 70.85  ? 53  ALA D N   1 
ATOM 3291 C CA  . ALA B 2 47  ? 147.624 178.618 163.029 1.00 70.85  ? 53  ALA D CA  1 
ATOM 3292 C C   . ALA B 2 47  ? 148.530 178.375 164.212 1.00 70.85  ? 53  ALA D C   1 
ATOM 3293 O O   . ALA B 2 47  ? 149.452 179.168 164.432 1.00 70.85  ? 53  ALA D O   1 
ATOM 3294 C CB  . ALA B 2 47  ? 146.760 179.854 163.283 1.00 70.85  ? 53  ALA D CB  1 
ATOM 3295 N N   . ALA B 2 48  ? 148.311 177.309 164.980 1.00 68.05  ? 54  ALA D N   1 
ATOM 3296 C CA  . ALA B 2 48  ? 149.124 177.044 166.158 1.00 68.05  ? 54  ALA D CA  1 
ATOM 3297 C C   . ALA B 2 48  ? 149.660 175.620 166.153 1.00 68.05  ? 54  ALA D C   1 
ATOM 3298 O O   . ALA B 2 48  ? 150.687 175.339 166.778 1.00 68.05  ? 54  ALA D O   1 
ATOM 3299 C CB  . ALA B 2 48  ? 148.315 177.295 167.431 1.00 68.05  ? 54  ALA D CB  1 
ATOM 3300 N N   . CYS B 2 49  ? 148.974 174.712 165.456 1.00 70.00  ? 55  CYS D N   1 
ATOM 3301 C CA  . CYS B 2 49  ? 149.442 173.332 165.412 1.00 70.00  ? 55  CYS D CA  1 
ATOM 3302 C C   . CYS B 2 49  ? 150.759 173.208 164.659 1.00 70.00  ? 55  CYS D C   1 
ATOM 3303 O O   . CYS B 2 49  ? 151.644 172.456 165.082 1.00 70.00  ? 55  CYS D O   1 
ATOM 3304 C CB  . CYS B 2 49  ? 148.383 172.435 164.778 1.00 70.00  ? 55  CYS D CB  1 
ATOM 3305 S SG  . CYS B 2 49  ? 148.817 170.688 164.783 1.00 70.00  ? 55  CYS D SG  1 
ATOM 3306 N N   . SER B 2 50  ? 150.913 173.935 163.555 1.00 79.67  ? 56  SER D N   1 
ATOM 3307 C CA  . SER B 2 50  ? 152.130 173.927 162.765 1.00 79.67  ? 56  SER D CA  1 
ATOM 3308 C C   . SER B 2 50  ? 152.816 175.290 162.876 1.00 79.67  ? 56  SER D C   1 
ATOM 3309 O O   . SER B 2 50  ? 152.323 176.192 163.568 1.00 79.67  ? 56  SER D O   1 
ATOM 3310 C CB  . SER B 2 50  ? 151.793 173.548 161.322 1.00 79.67  ? 56  SER D CB  1 
ATOM 3311 O OG  . SER B 2 50  ? 152.891 172.911 160.694 1.00 79.67  ? 56  SER D OG  1 
ATOM 3312 N N   . SER B 2 51  ? 153.948 175.440 162.197 1.00 82.81  ? 57  SER D N   1 
ATOM 3313 C CA  . SER B 2 51  ? 154.686 176.698 162.222 1.00 82.81  ? 57  SER D CA  1 
ATOM 3314 C C   . SER B 2 51  ? 154.983 177.147 160.793 1.00 82.81  ? 57  SER D C   1 
ATOM 3315 O O   . SER B 2 51  ? 155.922 177.902 160.534 1.00 82.81  ? 57  SER D O   1 
ATOM 3316 C CB  . SER B 2 51  ? 155.964 176.566 163.049 1.00 82.81  ? 57  SER D CB  1 
ATOM 3317 O OG  . SER B 2 51  ? 156.316 177.806 163.637 1.00 82.81  ? 57  SER D OG  1 
ATOM 3318 N N   . TYR B 2 52  ? 154.176 176.678 159.844 1.00 90.75  ? 58  TYR D N   1 
ATOM 3319 C CA  . TYR B 2 52  ? 154.214 177.180 158.476 1.00 90.75  ? 58  TYR D CA  1 
ATOM 3320 C C   . TYR B 2 52  ? 152.833 177.731 158.154 1.00 90.75  ? 58  TYR D C   1 
ATOM 3321 O O   . TYR B 2 52  ? 152.687 178.714 157.414 1.00 90.75  ? 58  TYR D O   1 
ATOM 3322 C CB  . TYR B 2 52  ? 154.619 176.075 157.499 1.00 90.75  ? 58  TYR D CB  1 
ATOM 3323 C CG  . TYR B 2 52  ? 154.560 176.479 156.044 1.00 90.75  ? 58  TYR D CG  1 
ATOM 3324 C CD1 . TYR B 2 52  ? 155.351 177.510 155.558 1.00 90.75  ? 58  TYR D CD1 1 
ATOM 3325 C CD2 . TYR B 2 52  ? 153.723 175.821 155.153 1.00 90.75  ? 58  TYR D CD2 1 
ATOM 3326 C CE1 . TYR B 2 52  ? 155.305 177.879 154.229 1.00 90.75  ? 58  TYR D CE1 1 
ATOM 3327 C CE2 . TYR B 2 52  ? 153.670 176.183 153.823 1.00 90.75  ? 58  TYR D CE2 1 
ATOM 3328 C CZ  . TYR B 2 52  ? 154.463 177.212 153.367 1.00 90.75  ? 58  TYR D CZ  1 
ATOM 3329 O OH  . TYR B 2 52  ? 154.414 177.576 152.042 1.00 90.75  ? 58  TYR D OH  1 
ATOM 3330 N N   . PHE B 2 53  ? 151.818 177.111 158.743 1.00 84.12  ? 59  PHE D N   1 
ATOM 3331 C CA  . PHE B 2 53  ? 150.455 177.636 158.741 1.00 84.12  ? 59  PHE D CA  1 
ATOM 3332 C C   . PHE B 2 53  ? 150.290 178.689 159.829 1.00 84.12  ? 59  PHE D C   1 
ATOM 3333 O O   . PHE B 2 53  ? 149.186 179.012 160.258 1.00 84.12  ? 59  PHE D O   1 
ATOM 3334 C CB  . PHE B 2 53  ? 149.452 176.503 158.915 1.00 84.12  ? 59  PHE D CB  1 
ATOM 3335 C CG  . PHE B 2 53  ? 149.460 175.507 157.794 1.00 84.12  ? 59  PHE D CG  1 
ATOM 3336 C CD1 . PHE B 2 53  ? 149.239 175.910 156.491 1.00 84.12  ? 59  PHE D CD1 1 
ATOM 3337 C CD2 . PHE B 2 53  ? 149.679 174.165 158.046 1.00 84.12  ? 59  PHE D CD2 1 
ATOM 3338 C CE1 . PHE B 2 53  ? 149.242 174.994 155.459 1.00 84.12  ? 59  PHE D CE1 1 
ATOM 3339 C CE2 . PHE B 2 53  ? 149.680 173.244 157.020 1.00 84.12  ? 59  PHE D CE2 1 
ATOM 3340 C CZ  . PHE B 2 53  ? 149.463 173.659 155.725 1.00 84.12  ? 59  PHE D CZ  1 
ATOM 3341 N N   . HIS B 2 54  ? 151.419 179.206 160.317 1.00 90.58  ? 60  HIS D N   1 
ATOM 3342 C CA  . HIS B 2 54  ? 151.393 180.423 161.120 1.00 90.58  ? 60  HIS D CA  1 
ATOM 3343 C C   . HIS B 2 54  ? 152.096 181.566 160.399 1.00 90.58  ? 60  HIS D C   1 
ATOM 3344 O O   . HIS B 2 54  ? 151.990 182.714 160.848 1.00 90.58  ? 60  HIS D O   1 
ATOM 3345 C CB  . HIS B 2 54  ? 152.038 180.192 162.493 1.00 90.58  ? 60  HIS D CB  1 
ATOM 3346 C CG  . HIS B 2 54  ? 151.784 181.296 163.472 1.00 90.58  ? 60  HIS D CG  1 
ATOM 3347 N ND1 . HIS B 2 54  ? 152.606 181.538 164.552 1.00 90.58  ? 60  HIS D ND1 1 
ATOM 3348 C CD2 . HIS B 2 54  ? 150.799 182.223 163.535 1.00 90.58  ? 60  HIS D CD2 1 
ATOM 3349 C CE1 . HIS B 2 54  ? 152.139 182.566 165.236 1.00 90.58  ? 60  HIS D CE1 1 
ATOM 3350 N NE2 . HIS B 2 54  ? 151.044 183.001 164.640 1.00 90.58  ? 60  HIS D NE2 1 
ATOM 3351 N N   . SER B 2 55  ? 152.799 181.298 159.298 1.00 96.79  ? 61  SER D N   1 
ATOM 3352 C CA  . SER B 2 55  ? 153.369 182.345 158.463 1.00 96.79  ? 61  SER D CA  1 
ATOM 3353 C C   . SER B 2 55  ? 152.630 182.476 157.138 1.00 96.79  ? 61  SER D C   1 
ATOM 3354 O O   . SER B 2 55  ? 152.769 183.505 156.467 1.00 96.79  ? 61  SER D O   1 
ATOM 3355 C CB  . SER B 2 55  ? 154.859 182.086 158.210 1.00 96.79  ? 61  SER D CB  1 
ATOM 3356 O OG  . SER B 2 55  ? 155.639 182.452 159.334 1.00 96.79  ? 61  SER D OG  1 
ATOM 3357 N N   . ARG B 2 56  ? 151.844 181.472 156.748 1.00 101.42 ? 62  ARG D N   1 
ATOM 3358 C CA  . ARG B 2 56  ? 151.013 181.609 155.556 1.00 101.42 ? 62  ARG D CA  1 
ATOM 3359 C C   . ARG B 2 56  ? 149.533 181.669 155.911 1.00 101.42 ? 62  ARG D C   1 
ATOM 3360 O O   . ARG B 2 56  ? 148.674 181.406 155.064 1.00 101.42 ? 62  ARG D O   1 
ATOM 3361 C CB  . ARG B 2 56  ? 151.288 180.469 154.578 1.00 101.42 ? 62  ARG D CB  1 
ATOM 3362 C CG  . ARG B 2 56  ? 152.743 180.380 154.195 1.00 101.42 ? 62  ARG D CG  1 
ATOM 3363 C CD  . ARG B 2 56  ? 153.055 181.433 153.154 1.00 101.42 ? 62  ARG D CD  1 
ATOM 3364 N NE  . ARG B 2 56  ? 154.481 181.719 153.072 1.00 101.42 ? 62  ARG D NE  1 
ATOM 3365 C CZ  . ARG B 2 56  ? 155.101 182.121 151.973 1.00 101.42 ? 62  ARG D CZ  1 
ATOM 3366 N NH1 . ARG B 2 56  ? 154.455 182.263 150.827 1.00 101.42 ? 62  ARG D NH1 1 
ATOM 3367 N NH2 . ARG B 2 56  ? 156.400 182.396 152.026 1.00 101.42 ? 62  ARG D NH2 1 
ATOM 3368 N N   . ILE B 2 57  ? 149.231 182.023 157.156 1.00 93.04  ? 63  ILE D N   1 
ATOM 3369 C CA  . ILE B 2 57  ? 147.855 182.174 157.607 1.00 93.04  ? 63  ILE D CA  1 
ATOM 3370 C C   . ILE B 2 57  ? 147.582 183.549 158.213 1.00 93.04  ? 63  ILE D C   1 
ATOM 3371 O O   . ILE B 2 57  ? 146.435 184.020 158.147 1.00 93.04  ? 63  ILE D O   1 
ATOM 3372 C CB  . ILE B 2 57  ? 147.482 181.051 158.601 1.00 93.04  ? 63  ILE D CB  1 
ATOM 3373 C CG1 . ILE B 2 57  ? 147.340 179.717 157.865 1.00 93.04  ? 63  ILE D CG1 1 
ATOM 3374 C CG2 . ILE B 2 57  ? 146.212 181.357 159.362 1.00 93.04  ? 63  ILE D CG2 1 
ATOM 3375 C CD1 . ILE B 2 57  ? 146.460 179.783 156.636 1.00 93.04  ? 63  ILE D CD1 1 
ATOM 3376 N N   . VAL B 2 58  ? 148.597 184.237 158.731 1.00 98.07  ? 64  VAL D N   1 
ATOM 3377 C CA  . VAL B 2 58  ? 148.394 185.534 159.369 1.00 98.07  ? 64  VAL D CA  1 
ATOM 3378 C C   . VAL B 2 58  ? 148.573 186.631 158.329 1.00 98.07  ? 64  VAL D C   1 
ATOM 3379 O O   . VAL B 2 58  ? 149.141 186.399 157.256 1.00 98.07  ? 64  VAL D O   1 
ATOM 3380 C CB  . VAL B 2 58  ? 149.359 185.738 160.549 1.00 98.07  ? 64  VAL D CB  1 
ATOM 3381 C CG1 . VAL B 2 58  ? 149.093 184.711 161.634 1.00 98.07  ? 64  VAL D CG1 1 
ATOM 3382 C CG2 . VAL B 2 58  ? 150.797 185.668 160.072 1.00 98.07  ? 64  VAL D CG2 1 
ATOM 3383 N N   . GLY B 2 59  ? 148.090 187.828 158.641 1.00 104.21 ? 65  GLY D N   1 
ATOM 3384 C CA  . GLY B 2 59  ? 148.136 188.928 157.694 1.00 104.21 ? 65  GLY D CA  1 
ATOM 3385 C C   . GLY B 2 59  ? 147.251 188.731 156.483 1.00 104.21 ? 65  GLY D C   1 
ATOM 3386 O O   . GLY B 2 59  ? 147.641 189.098 155.368 1.00 104.21 ? 65  GLY D O   1 
ATOM 3387 N N   . GLN B 2 60  ? 146.066 188.162 156.676 1.00 101.85 ? 66  GLN D N   1 
ATOM 3388 C CA  . GLN B 2 60  ? 145.105 187.973 155.597 1.00 101.85 ? 66  GLN D CA  1 
ATOM 3389 C C   . GLN B 2 60  ? 143.786 188.605 156.037 1.00 101.85 ? 66  GLN D C   1 
ATOM 3390 O O   . GLN B 2 60  ? 143.695 189.279 157.071 1.00 101.85 ? 66  GLN D O   1 
ATOM 3391 C CB  . GLN B 2 60  ? 144.950 186.487 155.245 1.00 101.85 ? 66  GLN D CB  1 
ATOM 3392 C CG  . GLN B 2 60  ? 146.196 185.649 155.469 1.00 101.85 ? 66  GLN D CG  1 
ATOM 3393 C CD  . GLN B 2 60  ? 147.005 185.454 154.204 1.00 101.85 ? 66  GLN D CD  1 
ATOM 3394 O OE1 . GLN B 2 60  ? 146.492 184.973 153.193 1.00 101.85 ? 66  GLN D OE1 1 
ATOM 3395 N NE2 . GLN B 2 60  ? 148.279 185.825 154.252 1.00 101.85 ? 66  GLN D NE2 1 
ATOM 3396 N N   . ALA B 2 61  ? 142.737 188.393 155.245 1.00 98.07  ? 67  ALA D N   1 
ATOM 3397 C CA  . ALA B 2 61  ? 141.420 188.914 155.583 1.00 98.07  ? 67  ALA D CA  1 
ATOM 3398 C C   . ALA B 2 61  ? 140.490 187.776 155.976 1.00 98.07  ? 67  ALA D C   1 
ATOM 3399 O O   . ALA B 2 61  ? 140.907 186.614 156.016 1.00 98.07  ? 67  ALA D O   1 
ATOM 3400 C CB  . ALA B 2 61  ? 140.835 189.703 154.411 1.00 98.07  ? 67  ALA D CB  1 
ATOM 3401 N N   . ASP B 2 62  ? 139.231 188.094 156.269 1.00 104.04 ? 68  ASP D N   1 
ATOM 3402 C CA  . ASP B 2 62  ? 138.243 187.081 156.607 1.00 104.04 ? 68  ASP D CA  1 
ATOM 3403 C C   . ASP B 2 62  ? 137.812 186.260 155.403 1.00 104.04 ? 68  ASP D C   1 
ATOM 3404 O O   . ASP B 2 62  ? 137.230 185.184 155.581 1.00 104.04 ? 68  ASP D O   1 
ATOM 3405 C CB  . ASP B 2 62  ? 137.016 187.728 157.259 1.00 104.04 ? 68  ASP D CB  1 
ATOM 3406 C CG  . ASP B 2 62  ? 136.490 186.922 158.430 1.00 104.04 ? 68  ASP D CG  1 
ATOM 3407 O OD1 . ASP B 2 62  ? 136.268 185.705 158.263 1.00 104.04 ? 68  ASP D OD1 1 
ATOM 3408 O OD2 . ASP B 2 62  ? 136.303 187.504 159.519 1.00 104.04 ? 68  ASP D OD2 1 
ATOM 3409 N N   . GLY B 2 63  ? 138.074 186.736 154.188 1.00 99.90  ? 69  GLY D N   1 
ATOM 3410 C CA  . GLY B 2 63  ? 137.820 185.933 153.005 1.00 99.90  ? 69  GLY D CA  1 
ATOM 3411 C C   . GLY B 2 63  ? 138.656 184.665 153.028 1.00 99.90  ? 69  GLY D C   1 
ATOM 3412 O O   . GLY B 2 63  ? 139.848 184.685 153.332 1.00 99.90  ? 69  GLY D O   1 
ATOM 3413 N N   . GLU B 2 64  ? 138.006 183.547 152.711 1.00 101.59 ? 70  GLU D N   1 
ATOM 3414 C CA  . GLU B 2 64  ? 138.648 182.244 152.820 1.00 101.59 ? 70  GLU D CA  1 
ATOM 3415 C C   . GLU B 2 64  ? 139.895 182.175 151.949 1.00 101.59 ? 70  GLU D C   1 
ATOM 3416 O O   . GLU B 2 64  ? 139.847 182.451 150.747 1.00 101.59 ? 70  GLU D O   1 
ATOM 3417 C CB  . GLU B 2 64  ? 137.661 181.145 152.423 1.00 101.59 ? 70  GLU D CB  1 
ATOM 3418 C CG  . GLU B 2 64  ? 138.298 179.783 152.214 1.00 101.59 ? 70  GLU D CG  1 
ATOM 3419 C CD  . GLU B 2 64  ? 137.279 178.710 151.893 1.00 101.59 ? 70  GLU D CD  1 
ATOM 3420 O OE1 . GLU B 2 64  ? 136.455 178.391 152.775 1.00 101.59 ? 70  GLU D OE1 1 
ATOM 3421 O OE2 . GLU B 2 64  ? 137.302 178.186 150.759 1.00 101.59 ? 70  GLU D OE2 1 
ATOM 3422 N N   . LEU B 2 65  ? 141.013 181.804 152.565 1.00 89.45  ? 71  LEU D N   1 
ATOM 3423 C CA  . LEU B 2 65  ? 142.286 181.670 151.872 1.00 89.45  ? 71  LEU D CA  1 
ATOM 3424 C C   . LEU B 2 65  ? 142.478 180.218 151.461 1.00 89.45  ? 71  LEU D C   1 
ATOM 3425 O O   . LEU B 2 65  ? 142.334 179.310 152.286 1.00 89.45  ? 71  LEU D O   1 
ATOM 3426 C CB  . LEU B 2 65  ? 143.457 182.123 152.748 1.00 89.45  ? 71  LEU D CB  1 
ATOM 3427 C CG  . LEU B 2 65  ? 143.483 183.519 153.387 1.00 89.45  ? 71  LEU D CG  1 
ATOM 3428 C CD1 . LEU B 2 65  ? 143.186 184.607 152.358 1.00 89.45  ? 71  LEU D CD1 1 
ATOM 3429 C CD2 . LEU B 2 65  ? 142.576 183.637 154.611 1.00 89.45  ? 71  LEU D CD2 1 
ATOM 3430 N N   . ASN B 2 66  ? 142.802 180.003 150.190 1.00 86.21  ? 72  ASN D N   1 
ATOM 3431 C CA  . ASN B 2 66  ? 143.024 178.670 149.644 1.00 86.21  ? 72  ASN D CA  1 
ATOM 3432 C C   . ASN B 2 66  ? 144.519 178.487 149.413 1.00 86.21  ? 72  ASN D C   1 
ATOM 3433 O O   . ASN B 2 66  ? 145.028 178.800 148.332 1.00 86.21  ? 72  ASN D O   1 
ATOM 3434 C CB  . ASN B 2 66  ? 142.237 178.472 148.351 1.00 86.21  ? 72  ASN D CB  1 
ATOM 3435 C CG  . ASN B 2 66  ? 140.810 178.963 148.460 1.00 86.21  ? 72  ASN D CG  1 
ATOM 3436 O OD1 . ASN B 2 66  ? 140.265 179.083 149.557 1.00 86.21  ? 72  ASN D OD1 1 
ATOM 3437 N ND2 . ASN B 2 66  ? 140.194 179.250 147.320 1.00 86.21  ? 72  ASN D ND2 1 
ATOM 3438 N N   . ILE B 2 67  ? 145.215 177.983 150.425 1.00 81.00  ? 73  ILE D N   1 
ATOM 3439 C CA  . ILE B 2 67  ? 146.648 177.755 150.326 1.00 81.00  ? 73  ILE D CA  1 
ATOM 3440 C C   . ILE B 2 67  ? 146.897 176.394 149.685 1.00 81.00  ? 73  ILE D C   1 
ATOM 3441 O O   . ILE B 2 67  ? 146.121 175.448 149.841 1.00 81.00  ? 73  ILE D O   1 
ATOM 3442 C CB  . ILE B 2 67  ? 147.336 177.871 151.704 1.00 81.00  ? 73  ILE D CB  1 
ATOM 3443 C CG1 . ILE B 2 67  ? 148.838 178.113 151.536 1.00 81.00  ? 73  ILE D CG1 1 
ATOM 3444 C CG2 . ILE B 2 67  ? 147.072 176.639 152.554 1.00 81.00  ? 73  ILE D CG2 1 
ATOM 3445 C CD1 . ILE B 2 67  ? 149.172 179.366 150.756 1.00 81.00  ? 73  ILE D CD1 1 
ATOM 3446 N N   . THR B 2 68  ? 147.989 176.304 148.927 1.00 72.80  ? 74  THR D N   1 
ATOM 3447 C CA  . THR B 2 68  ? 148.351 175.086 148.216 1.00 72.80  ? 74  THR D CA  1 
ATOM 3448 C C   . THR B 2 68  ? 149.766 174.679 148.595 1.00 72.80  ? 74  THR D C   1 
ATOM 3449 O O   . THR B 2 68  ? 150.627 175.535 148.818 1.00 72.80  ? 74  THR D O   1 
ATOM 3450 C CB  . THR B 2 68  ? 148.260 175.267 146.696 1.00 72.80  ? 74  THR D CB  1 
ATOM 3451 O OG1 . THR B 2 68  ? 149.464 175.875 146.215 1.00 72.80  ? 74  THR D OG1 1 
ATOM 3452 C CG2 . THR B 2 68  ? 147.075 176.142 146.326 1.00 72.80  ? 74  THR D CG2 1 
ATOM 3453 N N   . LEU B 2 69  ? 150.000 173.372 148.666 1.00 72.56  ? 75  LEU D N   1 
ATOM 3454 C CA  . LEU B 2 69  ? 151.312 172.835 148.984 1.00 72.56  ? 75  LEU D CA  1 
ATOM 3455 C C   . LEU B 2 69  ? 151.955 172.213 147.754 1.00 72.56  ? 75  LEU D C   1 
ATOM 3456 O O   . LEU B 2 69  ? 151.280 171.588 146.932 1.00 72.56  ? 75  LEU D O   1 
ATOM 3457 C CB  . LEU B 2 69  ? 151.210 171.791 150.101 1.00 72.56  ? 75  LEU D CB  1 
ATOM 3458 C CG  . LEU B 2 69  ? 151.305 172.283 151.549 1.00 72.56  ? 75  LEU D CG  1 
ATOM 3459 C CD1 . LEU B 2 69  ? 150.305 173.387 151.847 1.00 72.56  ? 75  LEU D CD1 1 
ATOM 3460 C CD2 . LEU B 2 69  ? 151.126 171.128 152.517 1.00 72.56  ? 75  LEU D CD2 1 
ATOM 3461 N N   . PRO B 2 70  ? 153.271 172.374 147.595 1.00 81.57  ? 76  PRO D N   1 
ATOM 3462 C CA  . PRO B 2 70  ? 153.953 171.811 146.419 1.00 81.57  ? 76  PRO D CA  1 
ATOM 3463 C C   . PRO B 2 70  ? 153.915 170.291 146.366 1.00 81.57  ? 76  PRO D C   1 
ATOM 3464 O O   . PRO B 2 70  ? 153.416 169.635 147.285 1.00 81.57  ? 76  PRO D O   1 
ATOM 3465 C CB  . PRO B 2 70  ? 155.397 172.316 146.562 1.00 81.57  ? 76  PRO D CB  1 
ATOM 3466 C CG  . PRO B 2 70  ? 155.470 173.047 147.868 1.00 81.57  ? 76  PRO D CG  1 
ATOM 3467 C CD  . PRO B 2 70  ? 154.087 173.380 148.291 1.00 81.57  ? 76  PRO D CD  1 
ATOM 3468 N N   . GLU B 2 71  ? 154.457 169.724 145.288 1.00 87.38  ? 77  GLU D N   1 
ATOM 3469 C CA  . GLU B 2 71  ? 154.476 168.284 145.075 1.00 87.38  ? 77  GLU D CA  1 
ATOM 3470 C C   . GLU B 2 71  ? 155.463 167.570 145.990 1.00 87.38  ? 77  GLU D C   1 
ATOM 3471 O O   . GLU B 2 71  ? 155.462 166.336 146.048 1.00 87.38  ? 77  GLU D O   1 
ATOM 3472 C CB  . GLU B 2 71  ? 154.798 167.970 143.613 1.00 87.38  ? 77  GLU D CB  1 
ATOM 3473 C CG  . GLU B 2 71  ? 153.592 167.583 142.774 1.00 87.38  ? 77  GLU D CG  1 
ATOM 3474 C CD  . GLU B 2 71  ? 152.546 168.678 142.714 1.00 87.38  ? 77  GLU D CD  1 
ATOM 3475 O OE1 . GLU B 2 71  ? 152.872 169.787 142.239 1.00 87.38  ? 77  GLU D OE1 1 
ATOM 3476 O OE2 . GLU B 2 71  ? 151.398 168.430 143.138 1.00 87.38  ? 77  GLU D OE2 1 
ATOM 3477 N N   . GLU B 2 72  ? 156.308 168.319 146.699 1.00 84.73  ? 78  GLU D N   1 
ATOM 3478 C CA  . GLU B 2 72  ? 157.278 167.698 147.595 1.00 84.73  ? 78  GLU D CA  1 
ATOM 3479 C C   . GLU B 2 72  ? 156.575 166.982 148.744 1.00 84.73  ? 78  GLU D C   1 
ATOM 3480 O O   . GLU B 2 72  ? 157.063 165.968 149.255 1.00 84.73  ? 78  GLU D O   1 
ATOM 3481 C CB  . GLU B 2 72  ? 158.267 168.754 148.099 1.00 84.73  ? 78  GLU D CB  1 
ATOM 3482 C CG  . GLU B 2 72  ? 158.981 168.412 149.392 1.00 84.73  ? 78  GLU D CG  1 
ATOM 3483 C CD  . GLU B 2 72  ? 159.219 169.629 150.258 1.00 84.73  ? 78  GLU D CD  1 
ATOM 3484 O OE1 . GLU B 2 72  ? 160.008 169.534 151.222 1.00 84.73  ? 78  GLU D OE1 1 
ATOM 3485 O OE2 . GLU B 2 72  ? 158.634 170.688 149.957 1.00 84.73  ? 78  GLU D OE2 1 
ATOM 3486 N N   . VAL B 2 73  ? 155.413 167.489 149.155 1.00 77.21  ? 79  VAL D N   1 
ATOM 3487 C CA  . VAL B 2 73  ? 154.542 166.750 150.061 1.00 77.21  ? 79  VAL D CA  1 
ATOM 3488 C C   . VAL B 2 73  ? 153.436 166.118 149.227 1.00 77.21  ? 79  VAL D C   1 
ATOM 3489 O O   . VAL B 2 73  ? 153.096 166.617 148.148 1.00 77.21  ? 79  VAL D O   1 
ATOM 3490 C CB  . VAL B 2 73  ? 153.968 167.652 151.168 1.00 77.21  ? 79  VAL D CB  1 
ATOM 3491 C CG1 . VAL B 2 73  ? 155.069 168.487 151.792 1.00 77.21  ? 79  VAL D CG1 1 
ATOM 3492 C CG2 . VAL B 2 73  ? 152.871 168.541 150.617 1.00 77.21  ? 79  VAL D CG2 1 
ATOM 3493 N N   . THR B 2 74  ? 152.878 165.013 149.706 1.00 74.20  ? 80  THR D N   1 
ATOM 3494 C CA  . THR B 2 74  ? 151.845 164.303 148.962 1.00 74.20  ? 80  THR D CA  1 
ATOM 3495 C C   . THR B 2 74  ? 150.643 164.107 149.881 1.00 74.20  ? 80  THR D C   1 
ATOM 3496 O O   . THR B 2 74  ? 150.604 164.649 150.991 1.00 74.20  ? 80  THR D O   1 
ATOM 3497 C CB  . THR B 2 74  ? 152.377 162.967 148.415 1.00 74.20  ? 80  THR D CB  1 
ATOM 3498 O OG1 . THR B 2 74  ? 152.189 161.938 149.395 1.00 74.20  ? 80  THR D OG1 1 
ATOM 3499 C CG2 . THR B 2 74  ? 153.851 163.066 148.054 1.00 74.20  ? 80  THR D CG2 1 
ATOM 3500 N N   . VAL B 2 75  ? 149.661 163.336 149.416 1.00 68.54  ? 81  VAL D N   1 
ATOM 3501 C CA  . VAL B 2 75  ? 148.479 163.040 150.214 1.00 68.54  ? 81  VAL D CA  1 
ATOM 3502 C C   . VAL B 2 75  ? 148.671 161.805 151.090 1.00 68.54  ? 81  VAL D C   1 
ATOM 3503 O O   . VAL B 2 75  ? 147.904 161.614 152.047 1.00 68.54  ? 81  VAL D O   1 
ATOM 3504 C CB  . VAL B 2 75  ? 147.240 162.867 149.310 1.00 68.54  ? 81  VAL D CB  1 
ATOM 3505 C CG1 . VAL B 2 75  ? 147.315 161.552 148.546 1.00 68.54  ? 81  VAL D CG1 1 
ATOM 3506 C CG2 . VAL B 2 75  ? 145.953 162.972 150.118 1.00 68.54  ? 81  VAL D CG2 1 
ATOM 3507 N N   . LYS B 2 76  ? 149.671 160.972 150.805 1.00 64.50  ? 82  LYS D N   1 
ATOM 3508 C CA  . LYS B 2 76  ? 149.962 159.806 151.628 1.00 64.50  ? 82  LYS D CA  1 
ATOM 3509 C C   . LYS B 2 76  ? 150.599 160.174 152.952 1.00 64.50  ? 82  LYS D C   1 
ATOM 3510 O O   . LYS B 2 76  ? 150.573 159.372 153.888 1.00 64.50  ? 82  LYS D O   1 
ATOM 3511 C CB  . LYS B 2 76  ? 150.871 158.836 150.870 1.00 64.50  ? 82  LYS D CB  1 
ATOM 3512 C CG  . LYS B 2 76  ? 150.836 157.412 151.399 1.00 64.50  ? 82  LYS D CG  1 
ATOM 3513 C CD  . LYS B 2 76  ? 150.869 156.403 150.262 1.00 64.50  ? 82  LYS D CD  1 
ATOM 3514 C CE  . LYS B 2 76  ? 152.034 156.662 149.318 1.00 64.50  ? 82  LYS D CE  1 
ATOM 3515 N NZ  . LYS B 2 76  ? 152.030 155.738 148.146 1.00 64.50  ? 82  LYS D NZ  1 
ATOM 3516 N N   . GLY B 2 77  ? 151.155 161.374 153.060 1.00 64.52  ? 83  GLY D N   1 
ATOM 3517 C CA  . GLY B 2 77  ? 151.794 161.794 154.287 1.00 64.52  ? 83  GLY D CA  1 
ATOM 3518 C C   . GLY B 2 77  ? 151.020 162.848 155.046 1.00 64.52  ? 83  GLY D C   1 
ATOM 3519 O O   . GLY B 2 77  ? 151.273 163.068 156.234 1.00 64.52  ? 83  GLY D O   1 
ATOM 3520 N N   . PHE B 2 78  ? 150.085 163.518 154.369 1.00 62.40  ? 84  PHE D N   1 
ATOM 3521 C CA  . PHE B 2 78  ? 149.296 164.554 155.023 1.00 62.40  ? 84  PHE D CA  1 
ATOM 3522 C C   . PHE B 2 78  ? 148.100 163.999 155.781 1.00 62.40  ? 84  PHE D C   1 
ATOM 3523 O O   . PHE B 2 78  ? 147.835 164.447 156.900 1.00 62.40  ? 84  PHE D O   1 
ATOM 3524 C CB  . PHE B 2 78  ? 148.809 165.575 154.001 1.00 62.40  ? 84  PHE D CB  1 
ATOM 3525 C CG  . PHE B 2 78  ? 148.924 166.987 154.463 1.00 62.40  ? 84  PHE D CG  1 
ATOM 3526 C CD1 . PHE B 2 78  ? 150.157 167.549 154.726 1.00 62.40  ? 84  PHE D CD1 1 
ATOM 3527 C CD2 . PHE B 2 78  ? 147.788 167.740 154.681 1.00 62.40  ? 84  PHE D CD2 1 
ATOM 3528 C CE1 . PHE B 2 78  ? 150.254 168.852 155.161 1.00 62.40  ? 84  PHE D CE1 1 
ATOM 3529 C CE2 . PHE B 2 78  ? 147.884 169.034 155.123 1.00 62.40  ? 84  PHE D CE2 1 
ATOM 3530 C CZ  . PHE B 2 78  ? 149.111 169.592 155.361 1.00 62.40  ? 84  PHE D CZ  1 
ATOM 3531 N N   . GLU B 2 79  ? 147.367 163.054 155.200 1.00 60.79  ? 85  GLU D N   1 
ATOM 3532 C CA  . GLU B 2 79  ? 146.166 162.554 155.866 1.00 60.79  ? 85  GLU D CA  1 
ATOM 3533 C C   . GLU B 2 79  ? 146.478 161.960 157.233 1.00 60.79  ? 85  GLU D C   1 
ATOM 3534 O O   . GLU B 2 79  ? 145.746 162.261 158.188 1.00 60.79  ? 85  GLU D O   1 
ATOM 3535 C CB  . GLU B 2 79  ? 145.443 161.557 154.952 1.00 60.79  ? 85  GLU D CB  1 
ATOM 3536 C CG  . GLU B 2 79  ? 144.425 160.617 155.619 1.00 60.79  ? 85  GLU D CG  1 
ATOM 3537 C CD  . GLU B 2 79  ? 143.420 161.295 156.555 1.00 60.79  ? 85  GLU D CD  1 
ATOM 3538 O OE1 . GLU B 2 79  ? 143.316 162.537 156.589 1.00 60.79  ? 85  GLU D OE1 1 
ATOM 3539 O OE2 . GLU B 2 79  ? 142.714 160.552 157.280 1.00 60.79  ? 85  GLU D OE2 1 
ATOM 3540 N N   . PRO B 2 80  ? 147.508 161.131 157.407 1.00 56.12  ? 86  PRO D N   1 
ATOM 3541 C CA  . PRO B 2 80  ? 148.002 160.828 158.723 1.00 56.12  ? 86  PRO D CA  1 
ATOM 3542 C C   . PRO B 2 80  ? 148.337 162.036 159.580 1.00 56.12  ? 86  PRO D C   1 
ATOM 3543 O O   . PRO B 2 80  ? 148.072 162.001 160.781 1.00 56.12  ? 86  PRO D O   1 
ATOM 3544 C CB  . PRO B 2 80  ? 149.272 160.092 158.301 1.00 56.12  ? 86  PRO D CB  1 
ATOM 3545 C CG  . PRO B 2 80  ? 148.717 159.872 156.773 1.00 56.12  ? 86  PRO D CG  1 
ATOM 3546 C CD  . PRO B 2 80  ? 147.585 159.668 156.895 1.00 56.12  ? 86  PRO D CD  1 
ATOM 3547 N N   . LEU B 2 81  ? 148.904 163.090 159.009 1.00 49.60  ? 87  LEU D N   1 
ATOM 3548 C CA  . LEU B 2 81  ? 149.396 164.213 159.795 1.00 49.60  ? 87  LEU D CA  1 
ATOM 3549 C C   . LEU B 2 81  ? 148.286 165.163 160.226 1.00 49.60  ? 87  LEU D C   1 
ATOM 3550 O O   . LEU B 2 81  ? 148.249 165.586 161.384 1.00 49.60  ? 87  LEU D O   1 
ATOM 3551 C CB  . LEU B 2 81  ? 150.458 164.978 158.999 1.00 49.60  ? 87  LEU D CB  1 
ATOM 3552 C CG  . LEU B 2 81  ? 151.443 165.794 159.822 1.00 49.60  ? 87  LEU D CG  1 
ATOM 3553 C CD1 . LEU B 2 81  ? 152.384 164.867 160.568 1.00 49.60  ? 87  LEU D CD1 1 
ATOM 3554 C CD2 . LEU B 2 81  ? 152.216 166.725 158.919 1.00 49.60  ? 87  LEU D CD2 1 
ATOM 3555 N N   . ILE B 2 82  ? 147.369 165.507 159.321 1.00 51.06  ? 88  ILE D N   1 
ATOM 3556 C CA  . ILE B 2 82  ? 146.289 166.413 159.686 1.00 51.06  ? 88  ILE D CA  1 
ATOM 3557 C C   . ILE B 2 82  ? 145.281 165.760 160.615 1.00 51.06  ? 88  ILE D C   1 
ATOM 3558 O O   . ILE B 2 82  ? 144.604 166.464 161.372 1.00 51.06  ? 88  ILE D O   1 
ATOM 3559 C CB  . ILE B 2 82  ? 145.576 166.972 158.438 1.00 51.06  ? 88  ILE D CB  1 
ATOM 3560 C CG1 . ILE B 2 82  ? 144.985 168.339 158.759 1.00 51.06  ? 88  ILE D CG1 1 
ATOM 3561 C CG2 . ILE B 2 82  ? 144.478 166.036 157.959 1.00 51.06  ? 88  ILE D CG2 1 
ATOM 3562 C CD1 . ILE B 2 82  ? 144.175 168.936 157.646 1.00 51.06  ? 88  ILE D CD1 1 
ATOM 3563 N N   . GLN B 2 83  ? 145.173 164.431 160.596 1.00 49.95  ? 89  GLN D N   1 
ATOM 3564 C CA  . GLN B 2 83  ? 144.339 163.711 161.546 1.00 49.95  ? 89  GLN D CA  1 
ATOM 3565 C C   . GLN B 2 83  ? 144.956 163.693 162.940 1.00 49.95  ? 89  GLN D C   1 
ATOM 3566 O O   . GLN B 2 83  ? 144.232 163.781 163.937 1.00 49.95  ? 89  GLN D O   1 
ATOM 3567 C CB  . GLN B 2 83  ? 144.083 162.292 161.040 1.00 49.95  ? 89  GLN D CB  1 
ATOM 3568 C CG  . GLN B 2 83  ? 143.671 161.304 162.104 1.00 49.95  ? 89  GLN D CG  1 
ATOM 3569 C CD  . GLN B 2 83  ? 143.523 159.899 161.565 1.00 49.95  ? 89  GLN D CD  1 
ATOM 3570 O OE1 . GLN B 2 83  ? 143.162 159.694 160.408 1.00 49.95  ? 89  GLN D OE1 1 
ATOM 3571 N NE2 . GLN B 2 83  ? 143.807 158.915 162.410 1.00 49.95  ? 89  GLN D NE2 1 
ATOM 3572 N N   . PHE B 2 84  ? 146.283 163.614 163.026 1.00 49.31  ? 90  PHE D N   1 
ATOM 3573 C CA  . PHE B 2 84  ? 146.987 163.835 164.277 1.00 49.31  ? 90  PHE D CA  1 
ATOM 3574 C C   . PHE B 2 84  ? 146.918 165.278 164.745 1.00 49.31  ? 90  PHE D C   1 
ATOM 3575 O O   . PHE B 2 84  ? 146.915 165.519 165.957 1.00 49.31  ? 90  PHE D O   1 
ATOM 3576 C CB  . PHE B 2 84  ? 148.460 163.419 164.146 1.00 49.31  ? 90  PHE D CB  1 
ATOM 3577 C CG  . PHE B 2 84  ? 149.317 163.871 165.287 1.00 49.31  ? 90  PHE D CG  1 
ATOM 3578 C CD1 . PHE B 2 84  ? 149.290 163.205 166.495 1.00 49.31  ? 90  PHE D CD1 1 
ATOM 3579 C CD2 . PHE B 2 84  ? 150.145 164.969 165.150 1.00 49.31  ? 90  PHE D CD2 1 
ATOM 3580 C CE1 . PHE B 2 84  ? 150.074 163.624 167.544 1.00 49.31  ? 90  PHE D CE1 1 
ATOM 3581 C CE2 . PHE B 2 84  ? 150.931 165.391 166.193 1.00 49.31  ? 90  PHE D CE2 1 
ATOM 3582 C CZ  . PHE B 2 84  ? 150.896 164.718 167.392 1.00 49.31  ? 90  PHE D CZ  1 
ATOM 3583 N N   . ALA B 2 85  ? 146.846 166.233 163.826 1.00 46.93  ? 91  ALA D N   1 
ATOM 3584 C CA  . ALA B 2 85  ? 146.686 167.640 164.161 1.00 46.93  ? 91  ALA D CA  1 
ATOM 3585 C C   . ALA B 2 85  ? 145.341 167.939 164.805 1.00 46.93  ? 91  ALA D C   1 
ATOM 3586 O O   . ALA B 2 85  ? 145.152 169.043 165.326 1.00 46.93  ? 91  ALA D O   1 
ATOM 3587 C CB  . ALA B 2 85  ? 146.855 168.501 162.906 1.00 46.93  ? 91  ALA D CB  1 
ATOM 3588 N N   . TYR B 2 86  ? 144.406 166.990 164.777 1.00 53.97  ? 92  TYR D N   1 
ATOM 3589 C CA  . TYR B 2 86  ? 143.090 167.196 165.360 1.00 53.97  ? 92  TYR D CA  1 
ATOM 3590 C C   . TYR B 2 86  ? 142.720 166.166 166.419 1.00 53.97  ? 92  TYR D C   1 
ATOM 3591 O O   . TYR B 2 86  ? 141.854 166.455 167.250 1.00 53.97  ? 92  TYR D O   1 
ATOM 3592 C CB  . TYR B 2 86  ? 142.019 167.191 164.260 1.00 53.97  ? 92  TYR D CB  1 
ATOM 3593 C CG  . TYR B 2 86  ? 141.770 168.544 163.641 1.00 53.97  ? 92  TYR D CG  1 
ATOM 3594 C CD1 . TYR B 2 86  ? 140.920 169.457 164.241 1.00 53.97  ? 92  TYR D CD1 1 
ATOM 3595 C CD2 . TYR B 2 86  ? 142.385 168.906 162.453 1.00 53.97  ? 92  TYR D CD2 1 
ATOM 3596 C CE1 . TYR B 2 86  ? 140.691 170.694 163.678 1.00 53.97  ? 92  TYR D CE1 1 
ATOM 3597 C CE2 . TYR B 2 86  ? 142.162 170.139 161.882 1.00 53.97  ? 92  TYR D CE2 1 
ATOM 3598 C CZ  . TYR B 2 86  ? 141.315 171.030 162.498 1.00 53.97  ? 92  TYR D CZ  1 
ATOM 3599 O OH  . TYR B 2 86  ? 141.090 172.261 161.930 1.00 53.97  ? 92  TYR D OH  1 
ATOM 3600 N N   . THR B 2 87  ? 143.337 164.983 166.424 1.00 50.04  ? 93  THR D N   1 
ATOM 3601 C CA  . THR B 2 87  ? 142.961 163.939 167.370 1.00 50.04  ? 93  THR D CA  1 
ATOM 3602 C C   . THR B 2 87  ? 144.129 163.518 168.251 1.00 50.04  ? 93  THR D C   1 
ATOM 3603 O O   . THR B 2 87  ? 143.958 162.695 169.156 1.00 50.04  ? 93  THR D O   1 
ATOM 3604 C CB  . THR B 2 87  ? 142.415 162.712 166.637 1.00 50.04  ? 93  THR D CB  1 
ATOM 3605 O OG1 . THR B 2 87  ? 143.505 161.943 166.114 1.00 50.04  ? 93  THR D OG1 1 
ATOM 3606 C CG2 . THR B 2 87  ? 141.507 163.126 165.500 1.00 50.04  ? 93  THR D CG2 1 
ATOM 3607 N N   . ALA B 2 88  ? 145.312 164.073 167.995 1.00 49.55  ? 94  ALA D N   1 
ATOM 3608 C CA  . ALA B 2 88  ? 146.529 163.734 168.732 1.00 49.55  ? 94  ALA D CA  1 
ATOM 3609 C C   . ALA B 2 88  ? 146.798 162.230 168.697 1.00 49.55  ? 94  ALA D C   1 
ATOM 3610 O O   . ALA B 2 88  ? 147.145 161.608 169.702 1.00 49.55  ? 94  ALA D O   1 
ATOM 3611 C CB  . ALA B 2 88  ? 146.460 164.247 170.171 1.00 49.55  ? 94  ALA D CB  1 
ATOM 3612 N N   . LYS B 2 89  ? 146.629 161.643 167.513 1.00 51.12  ? 95  LYS D N   1 
ATOM 3613 C CA  . LYS B 2 89  ? 146.919 160.231 167.295 1.00 51.12  ? 95  LYS D CA  1 
ATOM 3614 C C   . LYS B 2 89  ? 147.306 160.010 165.839 1.00 51.12  ? 95  LYS D C   1 
ATOM 3615 O O   . LYS B 2 89  ? 146.505 160.258 164.933 1.00 51.12  ? 95  LYS D O   1 
ATOM 3616 C CB  . LYS B 2 89  ? 145.719 159.364 167.676 1.00 51.12  ? 95  LYS D CB  1 
ATOM 3617 C CG  . LYS B 2 89  ? 145.707 157.995 167.019 1.00 51.12  ? 95  LYS D CG  1 
ATOM 3618 C CD  . LYS B 2 89  ? 144.579 157.135 167.562 1.00 51.12  ? 95  LYS D CD  1 
ATOM 3619 C CE  . LYS B 2 89  ? 144.935 155.659 167.514 1.00 51.12  ? 95  LYS D CE  1 
ATOM 3620 N NZ  . LYS B 2 89  ? 144.039 154.839 168.372 1.00 51.12  ? 95  LYS D NZ  1 
ATOM 3621 N N   . LEU B 2 90  ? 148.530 159.548 165.604 1.00 54.69  ? 96  LEU D N   1 
ATOM 3622 C CA  . LEU B 2 90  ? 149.112 159.481 164.265 1.00 54.69  ? 96  LEU D CA  1 
ATOM 3623 C C   . LEU B 2 90  ? 149.415 158.020 163.938 1.00 54.69  ? 96  LEU D C   1 
ATOM 3624 O O   . LEU B 2 90  ? 150.364 157.440 164.473 1.00 54.69  ? 96  LEU D O   1 
ATOM 3625 C CB  . LEU B 2 90  ? 150.357 160.361 164.192 1.00 54.69  ? 96  LEU D CB  1 
ATOM 3626 C CG  . LEU B 2 90  ? 151.246 160.368 162.953 1.00 54.69  ? 96  LEU D CG  1 
ATOM 3627 C CD1 . LEU B 2 90  ? 151.694 161.781 162.666 1.00 54.69  ? 96  LEU D CD1 1 
ATOM 3628 C CD2 . LEU B 2 90  ? 152.453 159.498 163.186 1.00 54.69  ? 96  LEU D CD2 1 
ATOM 3629 N N   . ILE B 2 91  ? 148.602 157.429 163.065 1.00 55.27  ? 97  ILE D N   1 
ATOM 3630 C CA  . ILE B 2 91  ? 148.757 156.030 162.674 1.00 55.27  ? 97  ILE D CA  1 
ATOM 3631 C C   . ILE B 2 91  ? 149.947 155.923 161.726 1.00 55.27  ? 97  ILE D C   1 
ATOM 3632 O O   . ILE B 2 91  ? 150.130 156.771 160.848 1.00 55.27  ? 97  ILE D O   1 
ATOM 3633 C CB  . ILE B 2 91  ? 147.480 155.483 162.026 1.00 55.27  ? 97  ILE D CB  1 
ATOM 3634 C CG1 . ILE B 2 91  ? 146.306 155.580 162.996 1.00 55.27  ? 97  ILE D CG1 1 
ATOM 3635 C CG2 . ILE B 2 91  ? 147.670 154.043 161.592 1.00 55.27  ? 97  ILE D CG2 1 
ATOM 3636 C CD1 . ILE B 2 91  ? 146.622 155.069 164.378 1.00 55.27  ? 97  ILE D CD1 1 
ATOM 3637 N N   . LEU B 2 92  ? 150.759 154.885 161.900 1.00 68.46  ? 98  LEU D N   1 
ATOM 3638 C CA  . LEU B 2 92  ? 151.911 154.637 161.048 1.00 68.46  ? 98  LEU D CA  1 
ATOM 3639 C C   . LEU B 2 92  ? 151.821 153.261 160.399 1.00 68.46  ? 98  LEU D C   1 
ATOM 3640 O O   . LEU B 2 92  ? 151.319 152.303 160.991 1.00 68.46  ? 98  LEU D O   1 
ATOM 3641 C CB  . LEU B 2 92  ? 153.208 154.756 161.847 1.00 68.46  ? 98  LEU D CB  1 
ATOM 3642 C CG  . LEU B 2 92  ? 153.650 156.196 162.086 1.00 68.46  ? 98  LEU D CG  1 
ATOM 3643 C CD1 . LEU B 2 92  ? 155.124 156.266 162.418 1.00 68.46  ? 98  LEU D CD1 1 
ATOM 3644 C CD2 . LEU B 2 92  ? 153.355 157.016 160.852 1.00 68.46  ? 98  LEU D CD2 1 
ATOM 3645 N N   . SER B 2 93  ? 152.317 153.176 159.168 1.00 78.57  ? 99  SER D N   1 
ATOM 3646 C CA  . SER B 2 93  ? 152.304 151.938 158.400 1.00 78.57  ? 99  SER D CA  1 
ATOM 3647 C C   . SER B 2 93  ? 153.569 151.896 157.552 1.00 78.57  ? 99  SER D C   1 
ATOM 3648 O O   . SER B 2 93  ? 154.354 152.847 157.530 1.00 78.57  ? 99  SER D O   1 
ATOM 3649 C CB  . SER B 2 93  ? 151.042 151.830 157.542 1.00 78.57  ? 99  SER D CB  1 
ATOM 3650 O OG  . SER B 2 93  ? 151.236 152.434 156.275 1.00 78.57  ? 99  SER D OG  1 
ATOM 3651 N N   . LYS B 2 94  ? 153.758 150.779 156.848 1.00 77.61  ? 100 LYS D N   1 
ATOM 3652 C CA  . LYS B 2 94  ? 154.978 150.531 156.087 1.00 77.61  ? 100 LYS D CA  1 
ATOM 3653 C C   . LYS B 2 94  ? 155.282 151.641 155.089 1.00 77.61  ? 100 LYS D C   1 
ATOM 3654 O O   . LYS B 2 94  ? 156.391 152.185 155.081 1.00 77.61  ? 100 LYS D O   1 
ATOM 3655 C CB  . LYS B 2 94  ? 154.878 149.192 155.355 1.00 77.61  ? 100 LYS D CB  1 
ATOM 3656 C CG  . LYS B 2 94  ? 156.199 148.687 154.808 1.00 77.61  ? 100 LYS D CG  1 
ATOM 3657 C CD  . LYS B 2 94  ? 156.204 147.174 154.705 1.00 77.61  ? 100 LYS D CD  1 
ATOM 3658 C CE  . LYS B 2 94  ? 157.521 146.667 154.146 1.00 77.61  ? 100 LYS D CE  1 
ATOM 3659 N NZ  . LYS B 2 94  ? 158.683 147.384 154.738 1.00 77.61  ? 100 LYS D NZ  1 
ATOM 3660 N N   . GLU B 2 95  ? 154.310 151.984 154.242 1.00 79.55  ? 101 GLU D N   1 
ATOM 3661 C CA  . GLU B 2 95  ? 154.547 153.008 153.230 1.00 79.55  ? 101 GLU D CA  1 
ATOM 3662 C C   . GLU B 2 95  ? 154.444 154.407 153.822 1.00 79.55  ? 101 GLU D C   1 
ATOM 3663 O O   . GLU B 2 95  ? 154.833 155.391 153.182 1.00 79.55  ? 101 GLU D O   1 
ATOM 3664 C CB  . GLU B 2 95  ? 153.571 152.858 152.057 1.00 79.55  ? 101 GLU D CB  1 
ATOM 3665 C CG  . GLU B 2 95  ? 153.415 151.456 151.447 1.00 79.55  ? 101 GLU D CG  1 
ATOM 3666 C CD  . GLU B 2 95  ? 152.788 150.433 152.378 1.00 79.55  ? 101 GLU D CD  1 
ATOM 3667 O OE1 . GLU B 2 95  ? 152.794 149.232 152.031 1.00 79.55  ? 101 GLU D OE1 1 
ATOM 3668 O OE2 . GLU B 2 95  ? 152.282 150.827 153.450 1.00 79.55  ? 101 GLU D OE2 1 
ATOM 3669 N N   . ASN B 2 96  ? 153.915 154.519 155.041 1.00 76.82  ? 102 ASN D N   1 
ATOM 3670 C CA  . ASN B 2 96  ? 153.667 155.835 155.619 1.00 76.82  ? 102 ASN D CA  1 
ATOM 3671 C C   . ASN B 2 96  ? 154.937 156.500 156.135 1.00 76.82  ? 102 ASN D C   1 
ATOM 3672 O O   . ASN B 2 96  ? 155.074 157.724 156.034 1.00 76.82  ? 102 ASN D O   1 
ATOM 3673 C CB  . ASN B 2 96  ? 152.644 155.723 156.749 1.00 76.82  ? 102 ASN D CB  1 
ATOM 3674 C CG  . ASN B 2 96  ? 151.321 156.364 156.398 1.00 76.82  ? 102 ASN D CG  1 
ATOM 3675 O OD1 . ASN B 2 96  ? 151.122 156.824 155.275 1.00 76.82  ? 102 ASN D OD1 1 
ATOM 3676 N ND2 . ASN B 2 96  ? 150.408 156.403 157.360 1.00 76.82  ? 102 ASN D ND2 1 
ATOM 3677 N N   . VAL B 2 97  ? 155.881 155.715 156.665 1.00 75.21  ? 103 VAL D N   1 
ATOM 3678 C CA  . VAL B 2 97  ? 156.928 156.261 157.533 1.00 75.21  ? 103 VAL D CA  1 
ATOM 3679 C C   . VAL B 2 97  ? 157.727 157.343 156.820 1.00 75.21  ? 103 VAL D C   1 
ATOM 3680 O O   . VAL B 2 97  ? 157.892 158.458 157.331 1.00 75.21  ? 103 VAL D O   1 
ATOM 3681 C CB  . VAL B 2 97  ? 157.853 155.139 158.032 1.00 75.21  ? 103 VAL D CB  1 
ATOM 3682 C CG1 . VAL B 2 97  ? 158.824 155.678 159.066 1.00 75.21  ? 103 VAL D CG1 1 
ATOM 3683 C CG2 . VAL B 2 97  ? 157.041 154.015 158.608 1.00 75.21  ? 103 VAL D CG2 1 
ATOM 3684 N N   . ASP B 2 98  ? 158.231 157.032 155.625 1.00 80.30  ? 104 ASP D N   1 
ATOM 3685 C CA  . ASP B 2 98  ? 159.120 157.958 154.933 1.00 80.30  ? 104 ASP D CA  1 
ATOM 3686 C C   . ASP B 2 98  ? 158.414 159.275 154.633 1.00 80.30  ? 104 ASP D C   1 
ATOM 3687 O O   . ASP B 2 98  ? 158.914 160.357 154.959 1.00 80.30  ? 104 ASP D O   1 
ATOM 3688 C CB  . ASP B 2 98  ? 159.641 157.319 153.644 1.00 80.30  ? 104 ASP D CB  1 
ATOM 3689 C CG  . ASP B 2 98  ? 159.852 155.823 153.777 1.00 80.30  ? 104 ASP D CG  1 
ATOM 3690 O OD1 . ASP B 2 98  ? 160.545 155.397 154.724 1.00 80.30  ? 104 ASP D OD1 1 
ATOM 3691 O OD2 . ASP B 2 98  ? 159.324 155.073 152.931 1.00 80.30  ? 104 ASP D OD2 1 
ATOM 3692 N N   . GLU B 2 99  ? 157.225 159.195 154.035 1.00 81.70  ? 105 GLU D N   1 
ATOM 3693 C CA  . GLU B 2 99  ? 156.536 160.409 153.614 1.00 81.70  ? 105 GLU D CA  1 
ATOM 3694 C C   . GLU B 2 99  ? 155.973 161.172 154.807 1.00 81.70  ? 105 GLU D C   1 
ATOM 3695 O O   . GLU B 2 99  ? 156.002 162.409 154.828 1.00 81.70  ? 105 GLU D O   1 
ATOM 3696 C CB  . GLU B 2 99  ? 155.431 160.060 152.618 1.00 81.70  ? 105 GLU D CB  1 
ATOM 3697 C CG  . GLU B 2 99  ? 155.931 159.790 151.199 1.00 81.70  ? 105 GLU D CG  1 
ATOM 3698 C CD  . GLU B 2 99  ? 156.339 161.042 150.439 1.00 81.70  ? 105 GLU D CD  1 
ATOM 3699 O OE1 . GLU B 2 99  ? 156.042 161.113 149.229 1.00 81.70  ? 105 GLU D OE1 1 
ATOM 3700 O OE2 . GLU B 2 99  ? 156.957 161.950 151.032 1.00 81.70  ? 105 GLU D OE2 1 
ATOM 3701 N N   . VAL B 2 100 ? 155.461 160.458 155.813 1.00 75.46  ? 106 VAL D N   1 
ATOM 3702 C CA  . VAL B 2 100 ? 154.917 161.143 156.982 1.00 75.46  ? 106 VAL D CA  1 
ATOM 3703 C C   . VAL B 2 100 ? 156.026 161.828 157.769 1.00 75.46  ? 106 VAL D C   1 
ATOM 3704 O O   . VAL B 2 100 ? 155.793 162.860 158.408 1.00 75.46  ? 106 VAL D O   1 
ATOM 3705 C CB  . VAL B 2 100 ? 154.109 160.171 157.862 1.00 75.46  ? 106 VAL D CB  1 
ATOM 3706 C CG1 . VAL B 2 100 ? 155.024 159.342 158.742 1.00 75.46  ? 106 VAL D CG1 1 
ATOM 3707 C CG2 . VAL B 2 100 ? 153.111 160.935 158.707 1.00 75.46  ? 106 VAL D CG2 1 
ATOM 3708 N N   . CYS B 2 101 ? 157.244 161.281 157.742 1.00 83.40  ? 107 CYS D N   1 
ATOM 3709 C CA  . CYS B 2 101 ? 158.362 161.970 158.377 1.00 83.40  ? 107 CYS D CA  1 
ATOM 3710 C C   . CYS B 2 101 ? 158.838 163.137 157.523 1.00 83.40  ? 107 CYS D C   1 
ATOM 3711 O O   . CYS B 2 101 ? 159.232 164.181 158.053 1.00 83.40  ? 107 CYS D O   1 
ATOM 3712 C CB  . CYS B 2 101 ? 159.505 160.989 158.640 1.00 83.40  ? 107 CYS D CB  1 
ATOM 3713 S SG  . CYS B 2 101 ? 161.143 161.748 158.729 1.00 83.40  ? 107 CYS D SG  1 
ATOM 3714 N N   . LYS B 2 102 ? 158.794 162.981 156.198 1.00 83.59  ? 108 LYS D N   1 
ATOM 3715 C CA  . LYS B 2 102 ? 159.234 164.044 155.300 1.00 83.59  ? 108 LYS D CA  1 
ATOM 3716 C C   . LYS B 2 102 ? 158.281 165.233 155.336 1.00 83.59  ? 108 LYS D C   1 
ATOM 3717 O O   . LYS B 2 102 ? 158.663 166.363 155.010 1.00 83.59  ? 108 LYS D O   1 
ATOM 3718 C CB  . LYS B 2 102 ? 159.358 163.491 153.880 1.00 83.59  ? 108 LYS D CB  1 
ATOM 3719 C CG  . LYS B 2 102 ? 160.372 164.204 153.010 1.00 83.59  ? 108 LYS D CG  1 
ATOM 3720 C CD  . LYS B 2 102 ? 160.553 163.473 151.692 1.00 83.59  ? 108 LYS D CD  1 
ATOM 3721 C CE  . LYS B 2 102 ? 159.569 163.970 150.649 1.00 83.59  ? 108 LYS D CE  1 
ATOM 3722 N NZ  . LYS B 2 102 ? 159.671 165.438 150.462 1.00 83.59  ? 108 LYS D NZ  1 
ATOM 3723 N N   . CYS B 2 103 ? 157.023 164.990 155.704 1.00 85.00  ? 109 CYS D N   1 
ATOM 3724 C CA  . CYS B 2 103 ? 156.061 166.085 155.793 1.00 85.00  ? 109 CYS D CA  1 
ATOM 3725 C C   . CYS B 2 103 ? 156.393 167.040 156.934 1.00 85.00  ? 109 CYS D C   1 
ATOM 3726 O O   . CYS B 2 103 ? 156.140 168.247 156.837 1.00 85.00  ? 109 CYS D O   1 
ATOM 3727 C CB  . CYS B 2 103 ? 154.646 165.532 155.963 1.00 85.00  ? 109 CYS D CB  1 
ATOM 3728 S SG  . CYS B 2 103 ? 153.961 164.747 154.490 1.00 85.00  ? 109 CYS D SG  1 
ATOM 3729 N N   . VAL B 2 104 ? 156.955 166.519 158.024 1.00 83.01  ? 110 VAL D N   1 
ATOM 3730 C CA  . VAL B 2 104 ? 157.090 167.269 159.270 1.00 83.01  ? 110 VAL D CA  1 
ATOM 3731 C C   . VAL B 2 104 ? 158.011 168.477 159.125 1.00 83.01  ? 110 VAL D C   1 
ATOM 3732 O O   . VAL B 2 104 ? 157.661 169.581 159.555 1.00 83.01  ? 110 VAL D O   1 
ATOM 3733 C CB  . VAL B 2 104 ? 157.582 166.354 160.405 1.00 83.01  ? 110 VAL D CB  1 
ATOM 3734 C CG1 . VAL B 2 104 ? 157.576 167.104 161.724 1.00 83.01  ? 110 VAL D CG1 1 
ATOM 3735 C CG2 . VAL B 2 104 ? 156.712 165.116 160.497 1.00 83.01  ? 110 VAL D CG2 1 
ATOM 3736 N N   . GLU B 2 105 ? 159.188 168.288 158.523 1.00 85.68  ? 111 GLU D N   1 
ATOM 3737 C CA  . GLU B 2 105 ? 160.174 169.366 158.517 1.00 85.68  ? 111 GLU D CA  1 
ATOM 3738 C C   . GLU B 2 105 ? 159.739 170.532 157.633 1.00 85.68  ? 111 GLU D C   1 
ATOM 3739 O O   . GLU B 2 105 ? 160.161 171.672 157.852 1.00 85.68  ? 111 GLU D O   1 
ATOM 3740 C CB  . GLU B 2 105 ? 161.554 168.855 158.083 1.00 85.68  ? 111 GLU D CB  1 
ATOM 3741 C CG  . GLU B 2 105 ? 161.955 167.461 158.565 1.00 85.68  ? 111 GLU D CG  1 
ATOM 3742 C CD  . GLU B 2 105 ? 161.307 166.341 157.781 1.00 85.68  ? 111 GLU D CD  1 
ATOM 3743 O OE1 . GLU B 2 105 ? 161.843 165.212 157.802 1.00 85.68  ? 111 GLU D OE1 1 
ATOM 3744 O OE2 . GLU B 2 105 ? 160.269 166.588 157.140 1.00 85.68  ? 111 GLU D OE2 1 
ATOM 3745 N N   . PHE B 2 106 ? 158.896 170.273 156.633 1.00 84.18  ? 112 PHE D N   1 
ATOM 3746 C CA  . PHE B 2 106 ? 158.395 171.359 155.797 1.00 84.18  ? 112 PHE D CA  1 
ATOM 3747 C C   . PHE B 2 106 ? 157.271 172.114 156.493 1.00 84.18  ? 112 PHE D C   1 
ATOM 3748 O O   . PHE B 2 106 ? 156.816 173.153 156.005 1.00 84.18  ? 112 PHE D O   1 
ATOM 3749 C CB  . PHE B 2 106 ? 157.896 170.836 154.450 1.00 84.18  ? 112 PHE D CB  1 
ATOM 3750 C CG  . PHE B 2 106 ? 157.826 171.891 153.385 1.00 84.18  ? 112 PHE D CG  1 
ATOM 3751 C CD1 . PHE B 2 106 ? 158.577 173.050 153.490 1.00 84.18  ? 112 PHE D CD1 1 
ATOM 3752 C CD2 . PHE B 2 106 ? 156.973 171.749 152.306 1.00 84.18  ? 112 PHE D CD2 1 
ATOM 3753 C CE1 . PHE B 2 106 ? 158.505 174.031 152.520 1.00 84.18  ? 112 PHE D CE1 1 
ATOM 3754 C CE2 . PHE B 2 106 ? 156.892 172.728 151.335 1.00 84.18  ? 112 PHE D CE2 1 
ATOM 3755 C CZ  . PHE B 2 106 ? 157.661 173.870 151.441 1.00 84.18  ? 112 PHE D CZ  1 
ATOM 3756 N N   . LEU B 2 107 ? 156.818 171.602 157.632 1.00 82.92  ? 113 LEU D N   1 
ATOM 3757 C CA  . LEU B 2 107 ? 155.702 172.218 158.332 1.00 82.92  ? 113 LEU D CA  1 
ATOM 3758 C C   . LEU B 2 107 ? 156.106 172.574 159.754 1.00 82.92  ? 113 LEU D C   1 
ATOM 3759 O O   . LEU B 2 107 ? 155.585 173.534 160.332 1.00 82.92  ? 113 LEU D O   1 
ATOM 3760 C CB  . LEU B 2 107 ? 154.499 171.277 158.333 1.00 82.92  ? 113 LEU D CB  1 
ATOM 3761 C CG  . LEU B 2 107 ? 153.861 171.040 156.967 1.00 82.92  ? 113 LEU D CG  1 
ATOM 3762 C CD1 . LEU B 2 107 ? 153.010 169.790 157.004 1.00 82.92  ? 113 LEU D CD1 1 
ATOM 3763 C CD2 . LEU B 2 107 ? 153.039 172.242 156.541 1.00 82.92  ? 113 LEU D CD2 1 
ATOM 3764 N N   . SER B 2 108 ? 157.045 171.809 160.314 1.00 84.67  ? 114 SER D N   1 
ATOM 3765 C CA  . SER B 2 108 ? 157.519 171.980 161.686 1.00 84.67  ? 114 SER D CA  1 
ATOM 3766 C C   . SER B 2 108 ? 156.340 172.020 162.663 1.00 84.67  ? 114 SER D C   1 
ATOM 3767 O O   . SER B 2 108 ? 156.225 172.892 163.526 1.00 84.67  ? 114 SER D O   1 
ATOM 3768 C CB  . SER B 2 108 ? 158.396 173.232 161.810 1.00 84.67  ? 114 SER D CB  1 
ATOM 3769 O OG  . SER B 2 108 ? 157.668 174.405 161.498 1.00 84.67  ? 114 SER D OG  1 
ATOM 3770 N N   . VAL B 2 109 ? 155.459 171.041 162.488 1.00 76.62  ? 115 VAL D N   1 
ATOM 3771 C CA  . VAL B 2 109 ? 154.293 170.874 163.347 1.00 76.62  ? 115 VAL D CA  1 
ATOM 3772 C C   . VAL B 2 109 ? 154.792 170.560 164.753 1.00 76.62  ? 115 VAL D C   1 
ATOM 3773 O O   . VAL B 2 109 ? 155.703 169.750 164.936 1.00 76.62  ? 115 VAL D O   1 
ATOM 3774 C CB  . VAL B 2 109 ? 153.348 169.791 162.808 1.00 76.62  ? 115 VAL D CB  1 
ATOM 3775 C CG1 . VAL B 2 109 ? 154.094 168.502 162.555 1.00 76.62  ? 115 VAL D CG1 1 
ATOM 3776 C CG2 . VAL B 2 109 ? 152.204 169.549 163.777 1.00 76.62  ? 115 VAL D CG2 1 
ATOM 3777 N N   . HIS B 2 110 ? 154.222 171.238 165.746 1.00 74.00  ? 116 HIS D N   1 
ATOM 3778 C CA  . HIS B 2 110 ? 154.754 171.178 167.100 1.00 74.00  ? 116 HIS D CA  1 
ATOM 3779 C C   . HIS B 2 110 ? 154.275 169.928 167.824 1.00 74.00  ? 116 HIS D C   1 
ATOM 3780 O O   . HIS B 2 110 ? 153.355 169.240 167.374 1.00 74.00  ? 116 HIS D O   1 
ATOM 3781 C CB  . HIS B 2 110 ? 154.340 172.426 167.879 1.00 74.00  ? 116 HIS D CB  1 
ATOM 3782 C CG  . HIS B 2 110 ? 154.947 173.690 167.358 1.00 74.00  ? 116 HIS D CG  1 
ATOM 3783 N ND1 . HIS B 2 110 ? 156.206 173.736 166.802 1.00 74.00  ? 116 HIS D ND1 1 
ATOM 3784 C CD2 . HIS B 2 110 ? 154.465 174.954 167.303 1.00 74.00  ? 116 HIS D CD2 1 
ATOM 3785 C CE1 . HIS B 2 110 ? 156.476 174.974 166.429 1.00 74.00  ? 116 HIS D CE1 1 
ATOM 3786 N NE2 . HIS B 2 110 ? 155.435 175.733 166.722 1.00 74.00  ? 116 HIS D NE2 1 
ATOM 3787 N N   . ASN B 2 111 ? 154.913 169.644 168.960 1.00 69.68  ? 117 ASN D N   1 
ATOM 3788 C CA  . ASN B 2 111 ? 154.579 168.546 169.864 1.00 69.68  ? 117 ASN D CA  1 
ATOM 3789 C C   . ASN B 2 111 ? 154.676 167.175 169.212 1.00 69.68  ? 117 ASN D C   1 
ATOM 3790 O O   . ASN B 2 111 ? 154.087 166.212 169.712 1.00 69.68  ? 117 ASN D O   1 
ATOM 3791 C CB  . ASN B 2 111 ? 153.189 168.719 170.484 1.00 69.68  ? 117 ASN D CB  1 
ATOM 3792 C CG  . ASN B 2 111 ? 152.809 170.172 170.664 1.00 69.68  ? 117 ASN D CG  1 
ATOM 3793 O OD1 . ASN B 2 111 ? 152.267 170.805 169.759 1.00 69.68  ? 117 ASN D OD1 1 
ATOM 3794 N ND2 . ASN B 2 111 ? 153.118 170.718 171.832 1.00 69.68  ? 117 ASN D ND2 1 
ATOM 3795 N N   . ILE B 2 112 ? 155.408 167.052 168.111 1.00 76.87  ? 118 ILE D N   1 
ATOM 3796 C CA  . ILE B 2 112 ? 155.719 165.763 167.508 1.00 76.87  ? 118 ILE D CA  1 
ATOM 3797 C C   . ILE B 2 112 ? 157.231 165.687 167.365 1.00 76.87  ? 118 ILE D C   1 
ATOM 3798 O O   . ILE B 2 112 ? 157.874 166.667 166.969 1.00 76.87  ? 118 ILE D O   1 
ATOM 3799 C CB  . ILE B 2 112 ? 155.021 165.573 166.153 1.00 76.87  ? 118 ILE D CB  1 
ATOM 3800 C CG1 . ILE B 2 112 ? 155.399 164.225 165.542 1.00 76.87  ? 118 ILE D CG1 1 
ATOM 3801 C CG2 . ILE B 2 112 ? 155.380 166.686 165.210 1.00 76.87  ? 118 ILE D CG2 1 
ATOM 3802 C CD1 . ILE B 2 112 ? 154.488 163.789 164.423 1.00 76.87  ? 118 ILE D CD1 1 
ATOM 3803 N N   . GLU B 2 113 ? 157.802 164.542 167.717 1.00 79.51  ? 119 GLU D N   1 
ATOM 3804 C CA  . GLU B 2 113 ? 159.248 164.377 167.677 1.00 79.51  ? 119 GLU D CA  1 
ATOM 3805 C C   . GLU B 2 113 ? 159.632 163.391 166.581 1.00 79.51  ? 119 GLU D C   1 
ATOM 3806 O O   . GLU B 2 113 ? 159.099 162.279 166.520 1.00 79.51  ? 119 GLU D O   1 
ATOM 3807 C CB  . GLU B 2 113 ? 159.753 163.938 169.047 1.00 79.51  ? 119 GLU D CB  1 
ATOM 3808 C CG  . GLU B 2 113 ? 158.788 163.044 169.789 1.00 79.51  ? 119 GLU D CG  1 
ATOM 3809 C CD  . GLU B 2 113 ? 159.152 162.903 171.249 1.00 79.51  ? 119 GLU D CD  1 
ATOM 3810 O OE1 . GLU B 2 113 ? 160.354 162.782 171.562 1.00 79.51  ? 119 GLU D OE1 1 
ATOM 3811 O OE2 . GLU B 2 113 ? 158.233 162.964 172.090 1.00 79.51  ? 119 GLU D OE2 1 
ATOM 3812 N N   . GLU B 2 114 ? 160.559 163.804 165.717 1.00 83.80  ? 120 GLU D N   1 
ATOM 3813 C CA  . GLU B 2 114 ? 160.872 163.056 164.507 1.00 83.80  ? 120 GLU D CA  1 
ATOM 3814 C C   . GLU B 2 114 ? 162.104 162.183 164.697 1.00 83.80  ? 120 GLU D C   1 
ATOM 3815 O O   . GLU B 2 114 ? 162.788 161.845 163.726 1.00 83.80  ? 120 GLU D O   1 
ATOM 3816 C CB  . GLU B 2 114 ? 161.089 164.007 163.327 1.00 83.80  ? 120 GLU D CB  1 
ATOM 3817 C CG  . GLU B 2 114 ? 161.758 165.335 163.679 1.00 83.80  ? 120 GLU D CG  1 
ATOM 3818 C CD  . GLU B 2 114 ? 160.793 166.384 164.208 1.00 83.80  ? 120 GLU D CD  1 
ATOM 3819 O OE1 . GLU B 2 114 ? 160.997 167.579 163.908 1.00 83.80  ? 120 GLU D OE1 1 
ATOM 3820 O OE2 . GLU B 2 114 ? 159.838 166.021 164.924 1.00 83.80  ? 120 GLU D OE2 1 
ATOM 3821 N N   . SER B 2 115 ? 162.397 161.810 165.941 1.00 70.62  ? 121 SER D N   1 
ATOM 3822 C CA  . SER B 2 115 ? 163.522 160.929 166.217 1.00 70.62  ? 121 SER D CA  1 
ATOM 3823 C C   . SER B 2 115 ? 163.011 159.596 166.740 1.00 70.62  ? 121 SER D C   1 
ATOM 3824 O O   . SER B 2 115 ? 163.712 158.583 166.675 1.00 70.62  ? 121 SER D O   1 
ATOM 3825 C CB  . SER B 2 115 ? 164.478 161.571 167.222 1.00 70.62  ? 121 SER D CB  1 
ATOM 3826 O OG  . SER B 2 115 ? 164.049 161.334 168.552 1.00 70.62  ? 121 SER D OG  1 
ATOM 3827 N N   . CYS B 2 116 ? 161.781 159.591 167.256 1.00 72.39  ? 122 CYS D N   1 
ATOM 3828 C CA  . CYS B 2 116 ? 161.187 158.349 167.729 1.00 72.39  ? 122 CYS D CA  1 
ATOM 3829 C C   . CYS B 2 116 ? 160.795 157.442 166.569 1.00 72.39  ? 122 CYS D C   1 
ATOM 3830 O O   . CYS B 2 116 ? 160.731 156.218 166.735 1.00 72.39  ? 122 CYS D O   1 
ATOM 3831 C CB  . CYS B 2 116 ? 159.977 158.656 168.610 1.00 72.39  ? 122 CYS D CB  1 
ATOM 3832 S SG  . CYS B 2 116 ? 158.867 157.264 168.908 1.00 72.39  ? 122 CYS D SG  1 
ATOM 3833 N N   . PHE B 2 117 ? 160.550 158.016 165.388 1.00 75.34  ? 123 PHE D N   1 
ATOM 3834 C CA  . PHE B 2 117 ? 160.152 157.213 164.235 1.00 75.34  ? 123 PHE D CA  1 
ATOM 3835 C C   . PHE B 2 117 ? 161.238 156.228 163.825 1.00 75.34  ? 123 PHE D C   1 
ATOM 3836 O O   . PHE B 2 117 ? 160.929 155.154 163.296 1.00 75.34  ? 123 PHE D O   1 
ATOM 3837 C CB  . PHE B 2 117 ? 159.794 158.119 163.059 1.00 75.34  ? 123 PHE D CB  1 
ATOM 3838 C CG  . PHE B 2 117 ? 158.577 158.962 163.294 1.00 75.34  ? 123 PHE D CG  1 
ATOM 3839 C CD1 . PHE B 2 117 ? 157.586 158.540 164.162 1.00 75.34  ? 123 PHE D CD1 1 
ATOM 3840 C CD2 . PHE B 2 117 ? 158.427 160.178 162.656 1.00 75.34  ? 123 PHE D CD2 1 
ATOM 3841 C CE1 . PHE B 2 117 ? 156.467 159.313 164.383 1.00 75.34  ? 123 PHE D CE1 1 
ATOM 3842 C CE2 . PHE B 2 117 ? 157.310 160.956 162.874 1.00 75.34  ? 123 PHE D CE2 1 
ATOM 3843 C CZ  . PHE B 2 117 ? 156.329 160.522 163.740 1.00 75.34  ? 123 PHE D CZ  1 
ATOM 3844 N N   . GLN B 2 118 ? 162.506 156.562 164.063 1.00 67.63  ? 124 GLN D N   1 
ATOM 3845 C CA  . GLN B 2 118 ? 163.596 155.661 163.711 1.00 67.63  ? 124 GLN D CA  1 
ATOM 3846 C C   . GLN B 2 118 ? 163.778 154.611 164.796 1.00 67.63  ? 124 GLN D C   1 
ATOM 3847 O O   . GLN B 2 118 ? 164.895 154.377 165.266 1.00 67.63  ? 124 GLN D O   1 
ATOM 3848 C CB  . GLN B 2 118 ? 164.891 156.448 163.508 1.00 67.63  ? 124 GLN D CB  1 
ATOM 3849 C CG  . GLN B 2 118 ? 165.579 156.193 162.184 1.00 67.63  ? 124 GLN D CG  1 
ATOM 3850 C CD  . GLN B 2 118 ? 166.463 157.349 161.766 1.00 67.63  ? 124 GLN D CD  1 
ATOM 3851 O OE1 . GLN B 2 118 ? 166.677 158.288 162.532 1.00 67.63  ? 124 GLN D OE1 1 
ATOM 3852 N NE2 . GLN B 2 118 ? 166.980 157.289 160.545 1.00 67.63  ? 124 GLN D NE2 1 
ATOM 3853 N N   . PHE B 2 119 ? 162.682 153.971 165.193 1.00 64.46  ? 125 PHE D N   1 
ATOM 3854 C CA  . PHE B 2 119 ? 162.709 152.933 166.212 1.00 64.46  ? 125 PHE D CA  1 
ATOM 3855 C C   . PHE B 2 119 ? 161.832 151.772 165.767 1.00 64.46  ? 125 PHE D C   1 
ATOM 3856 O O   . PHE B 2 119 ? 162.014 150.632 166.206 1.00 64.46  ? 125 PHE D O   1 
ATOM 3857 C CB  . PHE B 2 119 ? 162.242 153.501 167.555 1.00 64.46  ? 125 PHE D CB  1 
ATOM 3858 C CG  . PHE B 2 119 ? 161.756 152.462 168.521 1.00 64.46  ? 125 PHE D CG  1 
ATOM 3859 C CD1 . PHE B 2 119 ? 162.650 151.697 169.244 1.00 64.46  ? 125 PHE D CD1 1 
ATOM 3860 C CD2 . PHE B 2 119 ? 160.403 152.248 168.703 1.00 64.46  ? 125 PHE D CD2 1 
ATOM 3861 C CE1 . PHE B 2 119 ? 162.202 150.743 170.130 1.00 64.46  ? 125 PHE D CE1 1 
ATOM 3862 C CE2 . PHE B 2 119 ? 159.953 151.292 169.586 1.00 64.46  ? 125 PHE D CE2 1 
ATOM 3863 C CZ  . PHE B 2 119 ? 160.853 150.539 170.299 1.00 64.46  ? 125 PHE D CZ  1 
ATOM 3864 N N   . LEU B 2 120 ? 160.888 152.062 164.876 1.00 70.61  ? 126 LEU D N   1 
ATOM 3865 C CA  . LEU B 2 120 ? 159.902 151.082 164.452 1.00 70.61  ? 126 LEU D CA  1 
ATOM 3866 C C   . LEU B 2 120 ? 160.548 149.986 163.613 1.00 70.61  ? 126 LEU D C   1 
ATOM 3867 O O   . LEU B 2 120 ? 161.469 150.231 162.831 1.00 70.61  ? 126 LEU D O   1 
ATOM 3868 C CB  . LEU B 2 120 ? 158.801 151.767 163.648 1.00 70.61  ? 126 LEU D CB  1 
ATOM 3869 C CG  . LEU B 2 120 ? 158.167 152.982 164.325 1.00 70.61  ? 126 LEU D CG  1 
ATOM 3870 C CD1 . LEU B 2 120 ? 157.820 154.036 163.295 1.00 70.61  ? 126 LEU D CD1 1 
ATOM 3871 C CD2 . LEU B 2 120 ? 156.940 152.579 165.114 1.00 70.61  ? 126 LEU D CD2 1 
ATOM 3872 N N   . LYS B 2 121 ? 160.049 148.763 163.779 1.00 80.85  ? 127 LYS D N   1 
ATOM 3873 C CA  . LYS B 2 121 ? 160.541 147.646 162.984 1.00 80.85  ? 127 LYS D CA  1 
ATOM 3874 C C   . LYS B 2 121 ? 160.025 147.750 161.556 1.00 80.85  ? 127 LYS D C   1 
ATOM 3875 O O   . LYS B 2 121 ? 160.810 147.933 160.621 1.00 80.85  ? 127 LYS D O   1 
ATOM 3876 C CB  . LYS B 2 121 ? 160.119 146.315 163.608 1.00 80.85  ? 127 LYS D CB  1 
ATOM 3877 C CG  . LYS B 2 121 ? 160.484 145.091 162.782 1.00 80.85  ? 127 LYS D CG  1 
ATOM 3878 C CD  . LYS B 2 121 ? 161.951 145.099 162.383 1.00 80.85  ? 127 LYS D CD  1 
ATOM 3879 C CE  . LYS B 2 121 ? 162.553 143.706 162.457 1.00 80.85  ? 127 LYS D CE  1 
ATOM 3880 N NZ  . LYS B 2 121 ? 161.516 142.661 162.676 1.00 80.85  ? 127 LYS D NZ  1 
ATOM 3881 N N   . PHE B 2 122 ? 158.707 147.659 161.392 1.00 81.49  ? 128 PHE D N   1 
ATOM 3882 C CA  . PHE B 2 122 ? 158.046 147.788 160.094 1.00 81.49  ? 128 PHE D CA  1 
ATOM 3883 C C   . PHE B 2 122 ? 158.705 146.954 158.998 1.00 81.49  ? 128 PHE D C   1 
ATOM 3884 O O   . PHE B 2 122 ? 159.422 147.483 158.148 1.00 81.49  ? 128 PHE D O   1 
ATOM 3885 C CB  . PHE B 2 122 ? 158.005 149.257 159.677 1.00 81.49  ? 128 PHE D CB  1 
ATOM 3886 C CG  . PHE B 2 122 ? 156.820 149.999 160.216 1.00 81.49  ? 128 PHE D CG  1 
ATOM 3887 C CD1 . PHE B 2 122 ? 155.576 149.399 160.262 1.00 81.49  ? 128 PHE D CD1 1 
ATOM 3888 C CD2 . PHE B 2 122 ? 156.949 151.295 160.675 1.00 81.49  ? 128 PHE D CD2 1 
ATOM 3889 C CE1 . PHE B 2 122 ? 154.482 150.080 160.757 1.00 81.49  ? 128 PHE D CE1 1 
ATOM 3890 C CE2 . PHE B 2 122 ? 155.860 151.980 161.173 1.00 81.49  ? 128 PHE D CE2 1 
ATOM 3891 C CZ  . PHE B 2 122 ? 154.625 151.372 161.213 1.00 81.49  ? 128 PHE D CZ  1 
ATOM 3892 N N   . SER C 2 1   ? 151.361 144.885 161.020 1.00 77.18  ? 7   SER E N   1 
ATOM 3893 C CA  . SER C 2 1   ? 152.499 145.796 161.020 1.00 77.18  ? 7   SER E CA  1 
ATOM 3894 C C   . SER C 2 1   ? 152.043 147.243 160.901 1.00 77.18  ? 7   SER E C   1 
ATOM 3895 O O   . SER C 2 1   ? 152.398 147.938 159.950 1.00 77.18  ? 7   SER E O   1 
ATOM 3896 C CB  . SER C 2 1   ? 153.460 145.455 159.881 1.00 77.18  ? 7   SER E CB  1 
ATOM 3897 O OG  . SER C 2 1   ? 154.711 146.094 160.065 1.00 77.18  ? 7   SER E OG  1 
ATOM 3898 N N   . VAL C 2 2   ? 151.245 147.690 161.866 1.00 71.12  ? 8   VAL E N   1 
ATOM 3899 C CA  . VAL C 2 2   ? 150.763 149.064 161.927 1.00 71.12  ? 8   VAL E CA  1 
ATOM 3900 C C   . VAL C 2 2   ? 151.015 149.586 163.333 1.00 71.12  ? 8   VAL E C   1 
ATOM 3901 O O   . VAL C 2 2   ? 150.664 148.924 164.316 1.00 71.12  ? 8   VAL E O   1 
ATOM 3902 C CB  . VAL C 2 2   ? 149.271 149.159 161.560 1.00 71.12  ? 8   VAL E CB  1 
ATOM 3903 C CG1 . VAL C 2 2   ? 148.703 150.501 161.976 1.00 71.12  ? 8   VAL E CG1 1 
ATOM 3904 C CG2 . VAL C 2 2   ? 149.078 148.936 160.069 1.00 71.12  ? 8   VAL E CG2 1 
ATOM 3905 N N   . PHE C 2 3   ? 151.621 150.766 163.427 1.00 67.25  ? 9   PHE E N   1 
ATOM 3906 C CA  . PHE C 2 3   ? 151.977 151.356 164.707 1.00 67.25  ? 9   PHE E CA  1 
ATOM 3907 C C   . PHE C 2 3   ? 151.222 152.661 164.908 1.00 67.25  ? 9   PHE E C   1 
ATOM 3908 O O   . PHE C 2 3   ? 150.843 153.342 163.952 1.00 67.25  ? 9   PHE E O   1 
ATOM 3909 C CB  . PHE C 2 3   ? 153.483 151.609 164.815 1.00 67.25  ? 9   PHE E CB  1 
ATOM 3910 C CG  . PHE C 2 3   ? 154.255 150.440 165.344 1.00 67.25  ? 9   PHE E CG  1 
ATOM 3911 C CD1 . PHE C 2 3   ? 154.286 150.176 166.700 1.00 67.25  ? 9   PHE E CD1 1 
ATOM 3912 C CD2 . PHE C 2 3   ? 154.956 149.612 164.490 1.00 67.25  ? 9   PHE E CD2 1 
ATOM 3913 C CE1 . PHE C 2 3   ? 154.995 149.105 167.192 1.00 67.25  ? 9   PHE E CE1 1 
ATOM 3914 C CE2 . PHE C 2 3   ? 155.669 148.539 164.979 1.00 67.25  ? 9   PHE E CE2 1 
ATOM 3915 C CZ  . PHE C 2 3   ? 155.688 148.285 166.331 1.00 67.25  ? 9   PHE E CZ  1 
ATOM 3916 N N   . ALA C 2 4   ? 151.013 153.001 166.174 1.00 61.57  ? 10  ALA E N   1 
ATOM 3917 C CA  . ALA C 2 4   ? 150.300 154.204 166.566 1.00 61.57  ? 10  ALA E CA  1 
ATOM 3918 C C   . ALA C 2 4   ? 151.248 155.160 167.277 1.00 61.57  ? 10  ALA E C   1 
ATOM 3919 O O   . ALA C 2 4   ? 152.333 154.784 167.725 1.00 61.57  ? 10  ALA E O   1 
ATOM 3920 C CB  . ALA C 2 4   ? 149.109 153.868 167.470 1.00 61.57  ? 10  ALA E CB  1 
ATOM 3921 N N   . TYR C 2 5   ? 150.821 156.416 167.369 1.00 76.28  ? 11  TYR E N   1 
ATOM 3922 C CA  . TYR C 2 5   ? 151.579 157.449 168.075 1.00 76.28  ? 11  TYR E CA  1 
ATOM 3923 C C   . TYR C 2 5   ? 150.556 158.302 168.824 1.00 76.28  ? 11  TYR E C   1 
ATOM 3924 O O   . TYR C 2 5   ? 149.980 159.236 168.264 1.00 76.28  ? 11  TYR E O   1 
ATOM 3925 C CB  . TYR C 2 5   ? 152.415 158.284 167.117 1.00 76.28  ? 11  TYR E CB  1 
ATOM 3926 C CG  . TYR C 2 5   ? 153.252 159.351 167.782 1.00 76.28  ? 11  TYR E CG  1 
ATOM 3927 C CD1 . TYR C 2 5   ? 152.723 160.598 168.075 1.00 76.28  ? 11  TYR E CD1 1 
ATOM 3928 C CD2 . TYR C 2 5   ? 154.573 159.114 168.110 1.00 76.28  ? 11  TYR E CD2 1 
ATOM 3929 C CE1 . TYR C 2 5   ? 153.484 161.571 168.681 1.00 76.28  ? 11  TYR E CE1 1 
ATOM 3930 C CE2 . TYR C 2 5   ? 155.343 160.082 168.713 1.00 76.28  ? 11  TYR E CE2 1 
ATOM 3931 C CZ  . TYR C 2 5   ? 154.793 161.308 168.996 1.00 76.28  ? 11  TYR E CZ  1 
ATOM 3932 O OH  . TYR C 2 5   ? 155.560 162.276 169.598 1.00 76.28  ? 11  TYR E OH  1 
ATOM 3933 N N   . GLU C 2 6   ? 150.330 157.960 170.086 1.00 57.68  ? 12  GLU E N   1 
ATOM 3934 C CA  . GLU C 2 6   ? 149.357 158.662 170.910 1.00 57.68  ? 12  GLU E CA  1 
ATOM 3935 C C   . GLU C 2 6   ? 150.088 159.622 171.837 1.00 57.68  ? 12  GLU E C   1 
ATOM 3936 O O   . GLU C 2 6   ? 150.864 159.192 172.697 1.00 57.68  ? 12  GLU E O   1 
ATOM 3937 C CB  . GLU C 2 6   ? 148.514 157.670 171.708 1.00 57.68  ? 12  GLU E CB  1 
ATOM 3938 C CG  . GLU C 2 6   ? 147.608 158.312 172.737 1.00 57.68  ? 12  GLU E CG  1 
ATOM 3939 C CD  . GLU C 2 6   ? 146.502 157.382 173.192 1.00 57.68  ? 12  GLU E CD  1 
ATOM 3940 O OE1 . GLU C 2 6   ? 146.543 156.188 172.826 1.00 57.68  ? 12  GLU E OE1 1 
ATOM 3941 O OE2 . GLU C 2 6   ? 145.593 157.843 173.913 1.00 57.68  ? 12  GLU E OE2 1 
ATOM 3942 N N   . SER C 2 7   ? 149.841 160.914 171.664 1.00 47.52  ? 13  SER E N   1 
ATOM 3943 C CA  . SER C 2 7   ? 150.491 161.942 172.454 1.00 47.52  ? 13  SER E CA  1 
ATOM 3944 C C   . SER C 2 7   ? 149.632 162.280 173.669 1.00 47.52  ? 13  SER E C   1 
ATOM 3945 O O   . SER C 2 7   ? 148.440 161.966 173.725 1.00 47.52  ? 13  SER E O   1 
ATOM 3946 C CB  . SER C 2 7   ? 150.762 163.174 171.588 1.00 47.52  ? 13  SER E CB  1 
ATOM 3947 O OG  . SER C 2 7   ? 151.758 163.996 172.169 1.00 47.52  ? 13  SER E OG  1 
ATOM 3948 N N   . SER C 2 8   ? 150.246 162.927 174.663 1.00 51.93  ? 14  SER E N   1 
ATOM 3949 C CA  . SER C 2 8   ? 149.474 163.335 175.842 1.00 51.93  ? 14  SER E CA  1 
ATOM 3950 C C   . SER C 2 8   ? 149.676 164.802 176.191 1.00 51.93  ? 14  SER E C   1 
ATOM 3951 O O   . SER C 2 8   ? 149.209 165.229 177.253 1.00 51.93  ? 14  SER E O   1 
ATOM 3952 C CB  . SER C 2 8   ? 149.838 162.456 177.041 1.00 51.93  ? 14  SER E CB  1 
ATOM 3953 O OG  . SER C 2 8   ? 148.970 161.341 177.136 1.00 51.93  ? 14  SER E OG  1 
ATOM 3954 N N   . VAL C 2 9   ? 150.348 165.590 175.351 1.00 51.28  ? 15  VAL E N   1 
ATOM 3955 C CA  . VAL C 2 9   ? 150.570 167.004 175.614 1.00 51.28  ? 15  VAL E CA  1 
ATOM 3956 C C   . VAL C 2 9   ? 150.097 167.892 174.475 1.00 51.28  ? 15  VAL E C   1 
ATOM 3957 O O   . VAL C 2 9   ? 150.021 169.109 174.646 1.00 51.28  ? 15  VAL E O   1 
ATOM 3958 C CB  . VAL C 2 9   ? 152.054 167.284 175.926 1.00 51.28  ? 15  VAL E CB  1 
ATOM 3959 C CG1 . VAL C 2 9   ? 152.843 167.471 174.641 1.00 51.28  ? 15  VAL E CG1 1 
ATOM 3960 C CG2 . VAL C 2 9   ? 152.194 168.495 176.834 1.00 51.28  ? 15  VAL E CG2 1 
ATOM 3961 N N   . HIS C 2 10  ? 149.755 167.319 173.317 1.00 53.29  ? 16  HIS E N   1 
ATOM 3962 C CA  . HIS C 2 10  ? 149.332 168.135 172.183 1.00 53.29  ? 16  HIS E CA  1 
ATOM 3963 C C   . HIS C 2 10  ? 148.079 168.936 172.502 1.00 53.29  ? 16  HIS E C   1 
ATOM 3964 O O   . HIS C 2 10  ? 147.967 170.104 172.111 1.00 53.29  ? 16  HIS E O   1 
ATOM 3965 C CB  . HIS C 2 10  ? 149.086 167.260 170.957 1.00 53.29  ? 16  HIS E CB  1 
ATOM 3966 C CG  . HIS C 2 10  ? 149.040 168.031 169.677 1.00 53.29  ? 16  HIS E CG  1 
ATOM 3967 N ND1 . HIS C 2 10  ? 149.956 169.012 169.367 1.00 53.29  ? 16  HIS E ND1 1 
ATOM 3968 C CD2 . HIS C 2 10  ? 148.170 167.987 168.642 1.00 53.29  ? 16  HIS E CD2 1 
ATOM 3969 C CE1 . HIS C 2 10  ? 149.663 169.527 168.187 1.00 53.29  ? 16  HIS E CE1 1 
ATOM 3970 N NE2 . HIS C 2 10  ? 148.583 168.923 167.726 1.00 53.29  ? 16  HIS E NE2 1 
ATOM 3971 N N   . SER C 2 11  ? 147.118 168.322 173.189 1.00 49.55  ? 17  SER E N   1 
ATOM 3972 C CA  . SER C 2 11  ? 145.858 168.999 173.470 1.00 49.55  ? 17  SER E CA  1 
ATOM 3973 C C   . SER C 2 11  ? 146.083 170.248 174.314 1.00 49.55  ? 17  SER E C   1 
ATOM 3974 O O   . SER C 2 11  ? 145.579 171.332 173.995 1.00 49.55  ? 17  SER E O   1 
ATOM 3975 C CB  . SER C 2 11  ? 144.901 168.032 174.166 1.00 49.55  ? 17  SER E CB  1 
ATOM 3976 O OG  . SER C 2 11  ? 144.780 166.827 173.433 1.00 49.55  ? 17  SER E OG  1 
ATOM 3977 N N   . THR C 2 12  ? 146.859 170.117 175.392 1.00 51.13  ? 18  THR E N   1 
ATOM 3978 C CA  . THR C 2 12  ? 147.101 171.260 176.265 1.00 51.13  ? 18  THR E CA  1 
ATOM 3979 C C   . THR C 2 12  ? 147.867 172.366 175.553 1.00 51.13  ? 18  THR E C   1 
ATOM 3980 O O   . THR C 2 12  ? 147.520 173.543 175.694 1.00 51.13  ? 18  THR E O   1 
ATOM 3981 C CB  . THR C 2 12  ? 147.857 170.821 177.517 1.00 51.13  ? 18  THR E CB  1 
ATOM 3982 O OG1 . THR C 2 12  ? 147.243 169.647 178.062 1.00 51.13  ? 18  THR E OG1 1 
ATOM 3983 C CG2 . THR C 2 12  ? 147.839 171.925 178.560 1.00 51.13  ? 18  THR E CG2 1 
ATOM 3984 N N   . ASN C 2 13  ? 148.903 172.019 174.788 1.00 53.19  ? 19  ASN E N   1 
ATOM 3985 C CA  . ASN C 2 13  ? 149.659 173.049 174.086 1.00 53.19  ? 19  ASN E CA  1 
ATOM 3986 C C   . ASN C 2 13  ? 148.834 173.736 173.008 1.00 53.19  ? 19  ASN E C   1 
ATOM 3987 O O   . ASN C 2 13  ? 148.933 174.958 172.851 1.00 53.19  ? 19  ASN E O   1 
ATOM 3988 C CB  . ASN C 2 13  ? 150.934 172.467 173.477 1.00 53.19  ? 19  ASN E CB  1 
ATOM 3989 C CG  . ASN C 2 13  ? 151.743 171.663 174.473 1.00 53.19  ? 19  ASN E CG  1 
ATOM 3990 O OD1 . ASN C 2 13  ? 152.273 170.602 174.146 1.00 53.19  ? 19  ASN E OD1 1 
ATOM 3991 N ND2 . ASN C 2 13  ? 151.846 172.167 175.697 1.00 53.19  ? 19  ASN E ND2 1 
ATOM 3992 N N   . VAL C 2 14  ? 148.023 172.986 172.258 1.00 51.18  ? 20  VAL E N   1 
ATOM 3993 C CA  . VAL C 2 14  ? 147.210 173.633 171.235 1.00 51.18  ? 20  VAL E CA  1 
ATOM 3994 C C   . VAL C 2 14  ? 146.156 174.522 171.881 1.00 51.18  ? 20  VAL E C   1 
ATOM 3995 O O   . VAL C 2 14  ? 145.871 175.614 171.378 1.00 51.18  ? 20  VAL E O   1 
ATOM 3996 C CB  . VAL C 2 14  ? 146.592 172.599 170.271 1.00 51.18  ? 20  VAL E CB  1 
ATOM 3997 C CG1 . VAL C 2 14  ? 145.449 171.844 170.913 1.00 51.18  ? 20  VAL E CG1 1 
ATOM 3998 C CG2 . VAL C 2 14  ? 146.124 173.283 169.001 1.00 51.18  ? 20  VAL E CG2 1 
ATOM 3999 N N   . LEU C 2 15  ? 145.587 174.104 173.017 1.00 57.27  ? 21  LEU E N   1 
ATOM 4000 C CA  . LEU C 2 15  ? 144.641 174.959 173.720 1.00 57.27  ? 21  LEU E CA  1 
ATOM 4001 C C   . LEU C 2 15  ? 145.288 176.226 174.263 1.00 57.27  ? 21  LEU E C   1 
ATOM 4002 O O   . LEU C 2 15  ? 144.709 177.308 174.125 1.00 57.27  ? 21  LEU E O   1 
ATOM 4003 C CB  . LEU C 2 15  ? 143.977 174.187 174.860 1.00 57.27  ? 21  LEU E CB  1 
ATOM 4004 C CG  . LEU C 2 15  ? 142.554 174.616 175.207 1.00 57.27  ? 21  LEU E CG  1 
ATOM 4005 C CD1 . LEU C 2 15  ? 141.801 175.032 173.958 1.00 57.27  ? 21  LEU E CD1 1 
ATOM 4006 C CD2 . LEU C 2 15  ? 141.825 173.494 175.921 1.00 57.27  ? 21  LEU E CD2 1 
ATOM 4007 N N   . LEU C 2 16  ? 146.473 176.124 174.864 1.00 55.94  ? 22  LEU E N   1 
ATOM 4008 C CA  . LEU C 2 16  ? 147.188 177.303 175.332 1.00 55.94  ? 22  LEU E CA  1 
ATOM 4009 C C   . LEU C 2 16  ? 147.595 178.241 174.207 1.00 55.94  ? 22  LEU E C   1 
ATOM 4010 O O   . LEU C 2 16  ? 147.476 179.459 174.370 1.00 55.94  ? 22  LEU E O   1 
ATOM 4011 C CB  . LEU C 2 16  ? 148.433 176.903 176.133 1.00 55.94  ? 22  LEU E CB  1 
ATOM 4012 C CG  . LEU C 2 16  ? 148.277 176.688 177.641 1.00 55.94  ? 22  LEU E CG  1 
ATOM 4013 C CD1 . LEU C 2 16  ? 147.954 178.011 178.317 1.00 55.94  ? 22  LEU E CD1 1 
ATOM 4014 C CD2 . LEU C 2 16  ? 147.217 175.654 177.978 1.00 55.94  ? 22  LEU E CD2 1 
ATOM 4015 N N   . SER C 2 17  ? 148.064 177.717 173.076 1.00 56.41  ? 23  SER E N   1 
ATOM 4016 C CA  . SER C 2 17  ? 148.384 178.565 171.939 1.00 56.41  ? 23  SER E CA  1 
ATOM 4017 C C   . SER C 2 17  ? 147.152 179.211 171.326 1.00 56.41  ? 23  SER E C   1 
ATOM 4018 O O   . SER C 2 17  ? 147.219 180.375 170.915 1.00 56.41  ? 23  SER E O   1 
ATOM 4019 C CB  . SER C 2 17  ? 149.128 177.765 170.865 1.00 56.41  ? 23  SER E CB  1 
ATOM 4020 O OG  . SER C 2 17  ? 148.628 176.444 170.770 1.00 56.41  ? 23  SER E OG  1 
ATOM 4021 N N   . LEU C 2 18  ? 146.027 178.499 171.280 1.00 59.02  ? 24  LEU E N   1 
ATOM 4022 C CA  . LEU C 2 18  ? 144.778 179.108 170.856 1.00 59.02  ? 24  LEU E CA  1 
ATOM 4023 C C   . LEU C 2 18  ? 144.322 180.200 171.814 1.00 59.02  ? 24  LEU E C   1 
ATOM 4024 O O   . LEU C 2 18  ? 143.798 181.219 171.361 1.00 59.02  ? 24  LEU E O   1 
ATOM 4025 C CB  . LEU C 2 18  ? 143.706 178.027 170.716 1.00 59.02  ? 24  LEU E CB  1 
ATOM 4026 C CG  . LEU C 2 18  ? 142.691 178.182 169.584 1.00 59.02  ? 24  LEU E CG  1 
ATOM 4027 C CD1 . LEU C 2 18  ? 141.957 176.873 169.363 1.00 59.02  ? 24  LEU E CD1 1 
ATOM 4028 C CD2 . LEU C 2 18  ? 141.711 179.300 169.866 1.00 59.02  ? 24  LEU E CD2 1 
ATOM 4029 N N   . ASN C 2 19  ? 144.519 180.021 173.120 1.00 60.83  ? 25  ASN E N   1 
ATOM 4030 C CA  . ASN C 2 19  ? 144.260 181.077 174.091 1.00 60.83  ? 25  ASN E CA  1 
ATOM 4031 C C   . ASN C 2 19  ? 145.159 182.292 173.902 1.00 60.83  ? 25  ASN E C   1 
ATOM 4032 O O   . ASN C 2 19  ? 144.683 183.425 174.037 1.00 60.83  ? 25  ASN E O   1 
ATOM 4033 C CB  . ASN C 2 19  ? 144.429 180.536 175.516 1.00 60.83  ? 25  ASN E CB  1 
ATOM 4034 C CG  . ASN C 2 19  ? 144.342 181.620 176.565 1.00 60.83  ? 25  ASN E CG  1 
ATOM 4035 O OD1 . ASN C 2 19  ? 143.417 182.429 176.563 1.00 60.83  ? 25  ASN E OD1 1 
ATOM 4036 N ND2 . ASN C 2 19  ? 145.306 181.637 177.477 1.00 60.83  ? 25  ASN E ND2 1 
ATOM 4037 N N   . ASP C 2 20  ? 146.441 182.084 173.596 1.00 63.27  ? 26  ASP E N   1 
ATOM 4038 C CA  . ASP C 2 20  ? 147.317 183.200 173.260 1.00 63.27  ? 26  ASP E CA  1 
ATOM 4039 C C   . ASP C 2 20  ? 146.832 183.920 172.010 1.00 63.27  ? 26  ASP E C   1 
ATOM 4040 O O   . ASP C 2 20  ? 146.874 185.153 171.942 1.00 63.27  ? 26  ASP E O   1 
ATOM 4041 C CB  . ASP C 2 20  ? 148.750 182.703 173.068 1.00 63.27  ? 26  ASP E CB  1 
ATOM 4042 C CG  . ASP C 2 20  ? 149.602 182.889 174.307 1.00 63.27  ? 26  ASP E CG  1 
ATOM 4043 O OD1 . ASP C 2 20  ? 149.171 183.617 175.226 1.00 63.27  ? 26  ASP E OD1 1 
ATOM 4044 O OD2 . ASP C 2 20  ? 150.706 182.306 174.361 1.00 63.27  ? 26  ASP E OD2 1 
ATOM 4045 N N   . GLN C 2 21  ? 146.374 183.161 171.013 1.00 69.22  ? 27  GLN E N   1 
ATOM 4046 C CA  . GLN C 2 21  ? 145.778 183.771 169.830 1.00 69.22  ? 27  GLN E CA  1 
ATOM 4047 C C   . GLN C 2 21  ? 144.555 184.597 170.206 1.00 69.22  ? 27  GLN E C   1 
ATOM 4048 O O   . GLN C 2 21  ? 144.365 185.709 169.700 1.00 69.22  ? 27  GLN E O   1 
ATOM 4049 C CB  . GLN C 2 21  ? 145.404 182.685 168.824 1.00 69.22  ? 27  GLN E CB  1 
ATOM 4050 C CG  . GLN C 2 21  ? 146.584 182.128 168.051 1.00 69.22  ? 27  GLN E CG  1 
ATOM 4051 C CD  . GLN C 2 21  ? 146.161 181.308 166.853 1.00 69.22  ? 27  GLN E CD  1 
ATOM 4052 O OE1 . GLN C 2 21  ? 145.346 181.742 166.045 1.00 69.22  ? 27  GLN E OE1 1 
ATOM 4053 N NE2 . GLN C 2 21  ? 146.708 180.105 166.740 1.00 69.22  ? 27  GLN E NE2 1 
ATOM 4054 N N   . ARG C 2 22  ? 143.721 184.070 171.100 1.00 67.78  ? 28  ARG E N   1 
ATOM 4055 C CA  . ARG C 2 22  ? 142.557 184.742 171.671 1.00 67.78  ? 28  ARG E CA  1 
ATOM 4056 C C   . ARG C 2 22  ? 142.911 186.053 172.304 1.00 67.78  ? 28  ARG E C   1 
ATOM 4057 O O   . ARG C 2 22  ? 142.185 187.038 172.136 1.00 67.78  ? 28  ARG E O   1 
ATOM 4058 C CB  . ARG C 2 22  ? 141.887 183.820 172.696 1.00 67.78  ? 28  ARG E CB  1 
ATOM 4059 C CG  . ARG C 2 22  ? 140.424 184.129 173.015 1.00 67.78  ? 28  ARG E CG  1 
ATOM 4060 C CD  . ARG C 2 22  ? 140.264 185.294 173.980 1.00 67.78  ? 28  ARG E CD  1 
ATOM 4061 N NE  . ARG C 2 22  ? 141.050 185.125 175.194 1.00 67.78  ? 28  ARG E NE  1 
ATOM 4062 C CZ  . ARG C 2 22  ? 140.702 184.344 176.206 1.00 67.78  ? 28  ARG E CZ  1 
ATOM 4063 N NH1 . ARG C 2 22  ? 139.588 183.632 176.177 1.00 67.78  ? 28  ARG E NH1 1 
ATOM 4064 N NH2 . ARG C 2 22  ? 141.490 184.276 177.275 1.00 67.78  ? 28  ARG E NH2 1 
ATOM 4065 N N   . LYS C 2 23  ? 144.029 186.100 173.023 1.00 68.44  ? 29  LYS E N   1 
ATOM 4066 C CA  . LYS C 2 23  ? 144.453 187.341 173.656 1.00 68.44  ? 29  LYS E CA  1 
ATOM 4067 C C   . LYS C 2 23  ? 145.200 188.280 172.723 1.00 68.44  ? 29  LYS E C   1 
ATOM 4068 O O   . LYS C 2 23  ? 145.577 189.370 173.164 1.00 68.44  ? 29  LYS E O   1 
ATOM 4069 C CB  . LYS C 2 23  ? 145.338 187.046 174.875 1.00 68.44  ? 29  LYS E CB  1 
ATOM 4070 C CG  . LYS C 2 23  ? 144.584 187.007 176.193 1.00 68.44  ? 29  LYS E CG  1 
ATOM 4071 C CD  . LYS C 2 23  ? 145.539 187.001 177.373 1.00 68.44  ? 29  LYS E CD  1 
ATOM 4072 C CE  . LYS C 2 23  ? 145.398 185.731 178.191 1.00 68.44  ? 29  LYS E CE  1 
ATOM 4073 N NZ  . LYS C 2 23  ? 146.284 185.745 179.385 1.00 68.44  ? 29  LYS E NZ  1 
ATOM 4074 N N   . LYS C 2 24  ? 145.430 187.911 171.463 1.00 81.28  ? 30  LYS E N   1 
ATOM 4075 C CA  . LYS C 2 24  ? 146.203 188.728 170.528 1.00 81.28  ? 30  LYS E CA  1 
ATOM 4076 C C   . LYS C 2 24  ? 145.480 188.796 169.183 1.00 81.28  ? 30  LYS E C   1 
ATOM 4077 O O   . LYS C 2 24  ? 145.774 188.008 168.280 1.00 81.28  ? 30  LYS E O   1 
ATOM 4078 C CB  . LYS C 2 24  ? 147.613 188.163 170.382 1.00 81.28  ? 30  LYS E CB  1 
ATOM 4079 C CG  . LYS C 2 24  ? 148.612 189.104 169.733 1.00 81.28  ? 30  LYS E CG  1 
ATOM 4080 C CD  . LYS C 2 24  ? 150.015 188.885 170.283 1.00 81.28  ? 30  LYS E CD  1 
ATOM 4081 C CE  . LYS C 2 24  ? 150.325 187.407 170.493 1.00 81.28  ? 30  LYS E CE  1 
ATOM 4082 N NZ  . LYS C 2 24  ? 150.201 186.613 169.238 1.00 81.28  ? 30  LYS E NZ  1 
ATOM 4083 N N   . ASP C 2 25  ? 144.544 189.743 169.069 1.00 92.38  ? 31  ASP E N   1 
ATOM 4084 C CA  . ASP C 2 25  ? 143.942 190.189 167.813 1.00 92.38  ? 31  ASP E CA  1 
ATOM 4085 C C   . ASP C 2 25  ? 143.719 189.095 166.773 1.00 92.38  ? 31  ASP E C   1 
ATOM 4086 O O   . ASP C 2 25  ? 142.586 188.661 166.543 1.00 92.38  ? 31  ASP E O   1 
ATOM 4087 C CB  . ASP C 2 25  ? 144.808 191.286 167.190 1.00 92.38  ? 31  ASP E CB  1 
ATOM 4088 C CG  . ASP C 2 25  ? 145.121 192.403 168.162 1.00 92.38  ? 31  ASP E CG  1 
ATOM 4089 O OD1 . ASP C 2 25  ? 144.188 192.884 168.839 1.00 92.38  ? 31  ASP E OD1 1 
ATOM 4090 O OD2 . ASP C 2 25  ? 146.302 192.799 168.250 1.00 92.38  ? 31  ASP E OD2 1 
ATOM 4091 N N   . VAL C 2 26  ? 144.810 188.657 166.140 1.00 91.46  ? 32  VAL E N   1 
ATOM 4092 C CA  . VAL C 2 26  ? 144.734 187.896 164.897 1.00 91.46  ? 32  VAL E CA  1 
ATOM 4093 C C   . VAL C 2 26  ? 144.022 186.560 165.101 1.00 91.46  ? 32  VAL E C   1 
ATOM 4094 O O   . VAL C 2 26  ? 143.991 185.988 166.198 1.00 91.46  ? 32  VAL E O   1 
ATOM 4095 C CB  . VAL C 2 26  ? 146.146 187.699 164.324 1.00 91.46  ? 32  VAL E CB  1 
ATOM 4096 C CG1 . VAL C 2 26  ? 146.804 189.045 164.087 1.00 91.46  ? 32  VAL E CG1 1 
ATOM 4097 C CG2 . VAL C 2 26  ? 146.990 186.894 165.295 1.00 91.46  ? 32  VAL E CG2 1 
ATOM 4098 N N   . LEU C 2 27  ? 143.421 186.073 164.010 1.00 86.54  ? 33  LEU E N   1 
ATOM 4099 C CA  . LEU C 2 27  ? 142.687 184.809 163.946 1.00 86.54  ? 33  LEU E CA  1 
ATOM 4100 C C   . LEU C 2 27  ? 141.470 184.765 164.862 1.00 86.54  ? 33  LEU E C   1 
ATOM 4101 O O   . LEU C 2 27  ? 140.844 183.711 165.010 1.00 86.54  ? 33  LEU E O   1 
ATOM 4102 C CB  . LEU C 2 27  ? 143.592 183.608 164.242 1.00 86.54  ? 33  LEU E CB  1 
ATOM 4103 C CG  . LEU C 2 27  ? 144.762 183.248 163.317 1.00 86.54  ? 33  LEU E CG  1 
ATOM 4104 C CD1 . LEU C 2 27  ? 144.244 182.990 161.914 1.00 86.54  ? 33  LEU E CD1 1 
ATOM 4105 C CD2 . LEU C 2 27  ? 145.892 184.252 163.301 1.00 86.54  ? 33  LEU E CD2 1 
ATOM 4106 N N   . CYS C 2 28  ? 141.120 185.887 165.479 1.00 88.83  ? 34  CYS E N   1 
ATOM 4107 C CA  . CYS C 2 28  ? 139.876 185.953 166.229 1.00 88.83  ? 34  CYS E CA  1 
ATOM 4108 C C   . CYS C 2 28  ? 138.768 186.508 165.343 1.00 88.83  ? 34  CYS E C   1 
ATOM 4109 O O   . CYS C 2 28  ? 138.917 187.566 164.724 1.00 88.83  ? 34  CYS E O   1 
ATOM 4110 C CB  . CYS C 2 28  ? 140.053 186.814 167.474 1.00 88.83  ? 34  CYS E CB  1 
ATOM 4111 S SG  . CYS C 2 28  ? 140.397 185.879 168.981 1.00 88.83  ? 34  CYS E SG  1 
ATOM 4112 N N   . ASP C 2 29  ? 137.650 185.790 165.283 1.00 84.17  ? 35  ASP E N   1 
ATOM 4113 C CA  . ASP C 2 29  ? 136.619 186.050 164.283 1.00 84.17  ? 35  ASP E CA  1 
ATOM 4114 C C   . ASP C 2 29  ? 135.227 186.047 164.910 1.00 84.17  ? 35  ASP E C   1 
ATOM 4115 O O   . ASP C 2 29  ? 134.245 185.632 164.295 1.00 84.17  ? 35  ASP E O   1 
ATOM 4116 C CB  . ASP C 2 29  ? 136.723 185.028 163.154 1.00 84.17  ? 35  ASP E CB  1 
ATOM 4117 C CG  . ASP C 2 29  ? 137.137 183.659 163.651 1.00 84.17  ? 35  ASP E CG  1 
ATOM 4118 O OD1 . ASP C 2 29  ? 136.958 183.388 164.856 1.00 84.17  ? 35  ASP E OD1 1 
ATOM 4119 O OD2 . ASP C 2 29  ? 137.651 182.858 162.842 1.00 84.17  ? 35  ASP E OD2 1 
ATOM 4120 N N   . VAL C 2 30  ? 135.131 186.523 166.151 1.00 85.96  ? 36  VAL E N   1 
ATOM 4121 C CA  . VAL C 2 30  ? 133.843 186.758 166.797 1.00 85.96  ? 36  VAL E CA  1 
ATOM 4122 C C   . VAL C 2 30  ? 134.064 187.654 168.007 1.00 85.96  ? 36  VAL E C   1 
ATOM 4123 O O   . VAL C 2 30  ? 135.099 187.568 168.679 1.00 85.96  ? 36  VAL E O   1 
ATOM 4124 C CB  . VAL C 2 30  ? 133.150 185.440 167.198 1.00 85.96  ? 36  VAL E CB  1 
ATOM 4125 C CG1 . VAL C 2 30  ? 134.020 184.635 168.136 1.00 85.96  ? 36  VAL E CG1 1 
ATOM 4126 C CG2 . VAL C 2 30  ? 131.781 185.702 167.816 1.00 85.96  ? 36  VAL E CG2 1 
ATOM 4127 N N   . THR C 2 31  ? 133.102 188.528 168.287 1.00 91.50  ? 37  THR E N   1 
ATOM 4128 C CA  . THR C 2 31  ? 133.202 189.438 169.422 1.00 91.50  ? 37  THR E CA  1 
ATOM 4129 C C   . THR C 2 31  ? 131.974 189.260 170.298 1.00 91.50  ? 37  THR E C   1 
ATOM 4130 O O   . THR C 2 31  ? 130.849 189.234 169.791 1.00 91.50  ? 37  THR E O   1 
ATOM 4131 C CB  . THR C 2 31  ? 133.331 190.886 168.954 1.00 91.50  ? 37  THR E CB  1 
ATOM 4132 O OG1 . THR C 2 31  ? 132.290 191.178 168.014 1.00 91.50  ? 37  THR E OG1 1 
ATOM 4133 C CG2 . THR C 2 31  ? 134.681 191.099 168.288 1.00 91.50  ? 37  THR E CG2 1 
ATOM 4134 N N   . ILE C 2 32  ? 132.191 189.133 171.605 1.00 96.20  ? 38  ILE E N   1 
ATOM 4135 C CA  . ILE C 2 32  ? 131.111 188.929 172.564 1.00 96.20  ? 38  ILE E CA  1 
ATOM 4136 C C   . ILE C 2 32  ? 130.819 190.282 173.206 1.00 96.20  ? 38  ILE E C   1 
ATOM 4137 O O   . ILE C 2 32  ? 131.506 190.703 174.138 1.00 96.20  ? 38  ILE E O   1 
ATOM 4138 C CB  . ILE C 2 32  ? 131.473 187.878 173.615 1.00 96.20  ? 38  ILE E CB  1 
ATOM 4139 C CG1 . ILE C 2 32  ? 132.272 186.729 172.997 1.00 96.20  ? 38  ILE E CG1 1 
ATOM 4140 C CG2 . ILE C 2 32  ? 130.218 187.343 174.276 1.00 96.20  ? 38  ILE E CG2 1 
ATOM 4141 C CD1 . ILE C 2 32  ? 131.580 186.027 171.856 1.00 96.20  ? 38  ILE E CD1 1 
ATOM 4142 N N   . PHE C 2 33  ? 129.795 190.967 172.705 1.00 107.11 ? 39  PHE E N   1 
ATOM 4143 C CA  . PHE C 2 33  ? 129.356 192.231 173.289 1.00 107.11 ? 39  PHE E CA  1 
ATOM 4144 C C   . PHE C 2 33  ? 128.538 191.933 174.539 1.00 107.11 ? 39  PHE E C   1 
ATOM 4145 O O   . PHE C 2 33  ? 127.395 191.475 174.445 1.00 107.11 ? 39  PHE E O   1 
ATOM 4146 C CB  . PHE C 2 33  ? 128.541 193.031 172.278 1.00 107.11 ? 39  PHE E CB  1 
ATOM 4147 C CG  . PHE C 2 33  ? 128.924 194.480 172.197 1.00 107.11 ? 39  PHE E CG  1 
ATOM 4148 C CD1 . PHE C 2 33  ? 130.180 194.859 171.758 1.00 107.11 ? 39  PHE E CD1 1 
ATOM 4149 C CD2 . PHE C 2 33  ? 128.019 195.465 172.555 1.00 107.11 ? 39  PHE E CD2 1 
ATOM 4150 C CE1 . PHE C 2 33  ? 130.527 196.195 171.684 1.00 107.11 ? 39  PHE E CE1 1 
ATOM 4151 C CE2 . PHE C 2 33  ? 128.360 196.801 172.482 1.00 107.11 ? 39  PHE E CE2 1 
ATOM 4152 C CZ  . PHE C 2 33  ? 129.616 197.167 172.046 1.00 107.11 ? 39  PHE E CZ  1 
ATOM 4153 N N   . VAL C 2 34  ? 129.119 192.182 175.711 1.00 109.86 ? 40  VAL E N   1 
ATOM 4154 C CA  . VAL C 2 34  ? 128.464 191.909 176.983 1.00 109.86 ? 40  VAL E CA  1 
ATOM 4155 C C   . VAL C 2 34  ? 128.502 193.157 177.852 1.00 109.86 ? 40  VAL E C   1 
ATOM 4156 O O   . VAL C 2 34  ? 129.579 193.646 178.211 1.00 109.86 ? 40  VAL E O   1 
ATOM 4157 C CB  . VAL C 2 34  ? 129.117 190.718 177.715 1.00 109.86 ? 40  VAL E CB  1 
ATOM 4158 C CG1 . VAL C 2 34  ? 128.635 190.652 179.154 1.00 109.86 ? 40  VAL E CG1 1 
ATOM 4159 C CG2 . VAL C 2 34  ? 128.804 189.421 176.991 1.00 109.86 ? 40  VAL E CG2 1 
ATOM 4160 N N   . GLU C 2 35  ? 127.316 193.672 178.180 1.00 111.86 ? 41  GLU E N   1 
ATOM 4161 C CA  . GLU C 2 35  ? 127.125 194.717 179.189 1.00 111.86 ? 41  GLU E CA  1 
ATOM 4162 C C   . GLU C 2 35  ? 127.889 195.999 178.870 1.00 111.86 ? 41  GLU E C   1 
ATOM 4163 O O   . GLU C 2 35  ? 128.117 196.826 179.758 1.00 111.86 ? 41  GLU E O   1 
ATOM 4164 C CB  . GLU C 2 35  ? 127.508 194.207 180.581 1.00 111.86 ? 41  GLU E CB  1 
ATOM 4165 C CG  . GLU C 2 35  ? 126.445 193.334 181.217 1.00 111.86 ? 41  GLU E CG  1 
ATOM 4166 C CD  . GLU C 2 35  ? 127.013 192.391 182.253 1.00 111.86 ? 41  GLU E CD  1 
ATOM 4167 O OE1 . GLU C 2 35  ? 127.600 192.873 183.244 1.00 111.86 ? 41  GLU E OE1 1 
ATOM 4168 O OE2 . GLU C 2 35  ? 126.884 191.164 182.066 1.00 111.86 ? 41  GLU E OE2 1 
ATOM 4169 N N   . GLY C 2 36  ? 128.284 196.193 177.616 1.00 113.10 ? 42  GLY E N   1 
ATOM 4170 C CA  . GLY C 2 36  ? 128.968 197.413 177.237 1.00 113.10 ? 42  GLY E CA  1 
ATOM 4171 C C   . GLY C 2 36  ? 130.423 197.223 176.862 1.00 113.10 ? 42  GLY E C   1 
ATOM 4172 O O   . GLY C 2 36  ? 130.903 197.844 175.908 1.00 113.10 ? 42  GLY E O   1 
ATOM 4173 N N   . GLN C 2 37  ? 131.139 196.377 177.597 1.00 111.23 ? 43  GLN E N   1 
ATOM 4174 C CA  . GLN C 2 37  ? 132.536 196.106 177.291 1.00 111.23 ? 43  GLN E CA  1 
ATOM 4175 C C   . GLN C 2 37  ? 132.610 195.027 176.210 1.00 111.23 ? 43  GLN E C   1 
ATOM 4176 O O   . GLN C 2 37  ? 131.607 194.389 175.879 1.00 111.23 ? 43  GLN E O   1 
ATOM 4177 C CB  . GLN C 2 37  ? 133.310 195.727 178.563 1.00 111.23 ? 43  GLN E CB  1 
ATOM 4178 C CG  . GLN C 2 37  ? 133.097 196.628 179.787 1.00 111.23 ? 43  GLN E CG  1 
ATOM 4179 C CD  . GLN C 2 37  ? 131.755 196.438 180.474 1.00 111.23 ? 43  GLN E CD  1 
ATOM 4180 O OE1 . GLN C 2 37  ? 130.759 196.094 179.841 1.00 111.23 ? 43  GLN E OE1 1 
ATOM 4181 N NE2 . GLN C 2 37  ? 131.726 196.670 181.781 1.00 111.23 ? 43  GLN E NE2 1 
ATOM 4182 N N   . ARG C 2 38  ? 133.799 194.804 175.659 1.00 104.18 ? 44  ARG E N   1 
ATOM 4183 C CA  . ARG C 2 38  ? 133.987 193.941 174.506 1.00 104.18 ? 44  ARG E CA  1 
ATOM 4184 C C   . ARG C 2 38  ? 134.767 192.703 174.920 1.00 104.18 ? 44  ARG E C   1 
ATOM 4185 O O   . ARG C 2 38  ? 135.694 192.764 175.732 1.00 104.18 ? 44  ARG E O   1 
ATOM 4186 C CB  . ARG C 2 38  ? 134.727 194.683 173.383 1.00 104.18 ? 44  ARG E CB  1 
ATOM 4187 C CG  . ARG C 2 38  ? 133.950 195.841 172.773 1.00 104.18 ? 44  ARG E CG  1 
ATOM 4188 C CD  . ARG C 2 38  ? 134.620 196.359 171.507 1.00 104.18 ? 44  ARG E CD  1 
ATOM 4189 N NE  . ARG C 2 38  ? 134.724 195.352 170.458 1.00 104.18 ? 44  ARG E NE  1 
ATOM 4190 C CZ  . ARG C 2 38  ? 133.808 195.149 169.521 1.00 104.18 ? 44  ARG E CZ  1 
ATOM 4191 N NH1 . ARG C 2 38  ? 132.703 195.875 169.466 1.00 104.18 ? 44  ARG E NH1 1 
ATOM 4192 N NH2 . ARG C 2 38  ? 134.013 194.204 168.607 1.00 104.18 ? 44  ARG E NH2 1 
ATOM 4193 N N   . PHE C 2 39  ? 134.380 191.568 174.349 1.00 97.55  ? 45  PHE E N   1 
ATOM 4194 C CA  . PHE C 2 39  ? 135.133 190.335 174.512 1.00 97.55  ? 45  PHE E CA  1 
ATOM 4195 C C   . PHE C 2 39  ? 135.247 189.681 173.147 1.00 97.55  ? 45  PHE E C   1 
ATOM 4196 O O   . PHE C 2 39  ? 134.265 189.583 172.409 1.00 97.55  ? 45  PHE E O   1 
ATOM 4197 C CB  . PHE C 2 39  ? 134.471 189.381 175.512 1.00 97.55  ? 45  PHE E CB  1 
ATOM 4198 C CG  . PHE C 2 39  ? 134.666 189.777 176.944 1.00 97.55  ? 45  PHE E CG  1 
ATOM 4199 C CD1 . PHE C 2 39  ? 135.929 190.054 177.433 1.00 97.55  ? 45  PHE E CD1 1 
ATOM 4200 C CD2 . PHE C 2 39  ? 133.586 189.869 177.802 1.00 97.55  ? 45  PHE E CD2 1 
ATOM 4201 C CE1 . PHE C 2 39  ? 136.110 190.422 178.750 1.00 97.55  ? 45  PHE E CE1 1 
ATOM 4202 C CE2 . PHE C 2 39  ? 133.760 190.234 179.119 1.00 97.55  ? 45  PHE E CE2 1 
ATOM 4203 C CZ  . PHE C 2 39  ? 135.024 190.511 179.594 1.00 97.55  ? 45  PHE E CZ  1 
ATOM 4204 N N   . ARG C 2 40  ? 136.454 189.237 172.818 1.00 83.77  ? 46  ARG E N   1 
ATOM 4205 C CA  . ARG C 2 40  ? 136.748 188.710 171.498 1.00 83.77  ? 46  ARG E CA  1 
ATOM 4206 C C   . ARG C 2 40  ? 137.288 187.294 171.633 1.00 83.77  ? 46  ARG E C   1 
ATOM 4207 O O   . ARG C 2 40  ? 138.129 187.009 172.487 1.00 83.77  ? 46  ARG E O   1 
ATOM 4208 C CB  . ARG C 2 40  ? 137.737 189.625 170.765 1.00 83.77  ? 46  ARG E CB  1 
ATOM 4209 C CG  . ARG C 2 40  ? 138.516 188.967 169.661 1.00 83.77  ? 46  ARG E CG  1 
ATOM 4210 C CD  . ARG C 2 40  ? 138.874 189.974 168.581 1.00 83.77  ? 46  ARG E CD  1 
ATOM 4211 N NE  . ARG C 2 40  ? 137.850 190.040 167.546 1.00 83.77  ? 46  ARG E NE  1 
ATOM 4212 C CZ  . ARG C 2 40  ? 138.016 190.616 166.363 1.00 83.77  ? 46  ARG E CZ  1 
ATOM 4213 N NH1 . ARG C 2 40  ? 139.157 191.196 166.032 1.00 83.77  ? 46  ARG E NH1 1 
ATOM 4214 N NH2 . ARG C 2 40  ? 137.012 190.608 165.492 1.00 83.77  ? 46  ARG E NH2 1 
ATOM 4215 N N   . ALA C 2 41  ? 136.789 186.402 170.782 1.00 76.27  ? 47  ALA E N   1 
ATOM 4216 C CA  . ALA C 2 41  ? 137.054 184.973 170.918 1.00 76.27  ? 47  ALA E CA  1 
ATOM 4217 C C   . ALA C 2 41  ? 137.075 184.344 169.529 1.00 76.27  ? 47  ALA E C   1 
ATOM 4218 O O   . ALA C 2 41  ? 137.215 185.037 168.516 1.00 76.27  ? 47  ALA E O   1 
ATOM 4219 C CB  . ALA C 2 41  ? 136.016 184.314 171.831 1.00 76.27  ? 47  ALA E CB  1 
ATOM 4220 N N   . HIS C 2 42  ? 136.945 183.020 169.484 1.00 77.00  ? 48  HIS E N   1 
ATOM 4221 C CA  . HIS C 2 42  ? 136.973 182.251 168.246 1.00 77.00  ? 48  HIS E CA  1 
ATOM 4222 C C   . HIS C 2 42  ? 135.607 181.627 167.998 1.00 77.00  ? 48  HIS E C   1 
ATOM 4223 O O   . HIS C 2 42  ? 134.831 181.427 168.939 1.00 77.00  ? 48  HIS E O   1 
ATOM 4224 C CB  . HIS C 2 42  ? 138.043 181.160 168.309 1.00 77.00  ? 48  HIS E CB  1 
ATOM 4225 C CG  . HIS C 2 42  ? 139.443 181.685 168.313 1.00 77.00  ? 48  HIS E CG  1 
ATOM 4226 N ND1 . HIS C 2 42  ? 140.264 181.626 167.209 1.00 77.00  ? 48  HIS E ND1 1 
ATOM 4227 C CD2 . HIS C 2 42  ? 140.165 182.288 169.287 1.00 77.00  ? 48  HIS E CD2 1 
ATOM 4228 C CE1 . HIS C 2 42  ? 141.434 182.164 167.503 1.00 77.00  ? 48  HIS E CE1 1 
ATOM 4229 N NE2 . HIS C 2 42  ? 141.400 182.573 168.758 1.00 77.00  ? 48  HIS E NE2 1 
ATOM 4230 N N   . ARG C 2 43  ? 135.316 181.320 166.734 1.00 77.01  ? 49  ARG E N   1 
ATOM 4231 C CA  . ARG C 2 43  ? 134.039 180.714 166.354 1.00 77.01  ? 49  ARG E CA  1 
ATOM 4232 C C   . ARG C 2 43  ? 134.166 179.193 166.257 1.00 77.01  ? 49  ARG E C   1 
ATOM 4233 O O   . ARG C 2 43  ? 133.349 178.506 165.647 1.00 77.01  ? 49  ARG E O   1 
ATOM 4234 C CB  . ARG C 2 43  ? 133.537 181.303 165.041 1.00 77.01  ? 49  ARG E CB  1 
ATOM 4235 C CG  . ARG C 2 43  ? 132.868 182.651 165.181 1.00 77.01  ? 49  ARG E CG  1 
ATOM 4236 C CD  . ARG C 2 43  ? 132.181 183.092 163.897 1.00 77.01  ? 49  ARG E CD  1 
ATOM 4237 N NE  . ARG C 2 43  ? 133.064 183.022 162.741 1.00 77.01  ? 49  ARG E NE  1 
ATOM 4238 C CZ  . ARG C 2 43  ? 132.880 182.209 161.710 1.00 77.01  ? 49  ARG E CZ  1 
ATOM 4239 N NH1 . ARG C 2 43  ? 131.846 181.388 161.655 1.00 77.01  ? 49  ARG E NH1 1 
ATOM 4240 N NH2 . ARG C 2 43  ? 133.753 182.224 160.707 1.00 77.01  ? 49  ARG E NH2 1 
ATOM 4241 N N   . SER C 2 44  ? 135.219 178.667 166.875 1.00 71.44  ? 50  SER E N   1 
ATOM 4242 C CA  . SER C 2 44  ? 135.444 177.230 166.828 1.00 71.44  ? 50  SER E CA  1 
ATOM 4243 C C   . SER C 2 44  ? 135.451 176.641 168.231 1.00 71.44  ? 50  SER E C   1 
ATOM 4244 O O   . SER C 2 44  ? 134.867 175.580 168.469 1.00 71.44  ? 50  SER E O   1 
ATOM 4245 C CB  . SER C 2 44  ? 136.756 176.919 166.109 1.00 71.44  ? 50  SER E CB  1 
ATOM 4246 O OG  . SER C 2 44  ? 136.715 175.638 165.506 1.00 71.44  ? 50  SER E OG  1 
ATOM 4247 N N   . VAL C 2 45  ? 136.109 177.326 169.168 1.00 74.71  ? 51  VAL E N   1 
ATOM 4248 C CA  . VAL C 2 45  ? 136.128 176.855 170.551 1.00 74.71  ? 51  VAL E CA  1 
ATOM 4249 C C   . VAL C 2 45  ? 134.752 177.006 171.183 1.00 74.71  ? 51  VAL E C   1 
ATOM 4250 O O   . VAL C 2 45  ? 134.234 176.075 171.812 1.00 74.71  ? 51  VAL E O   1 
ATOM 4251 C CB  . VAL C 2 45  ? 137.205 177.605 171.355 1.00 74.71  ? 51  VAL E CB  1 
ATOM 4252 C CG1 . VAL C 2 45  ? 137.612 176.799 172.577 1.00 74.71  ? 51  VAL E CG1 1 
ATOM 4253 C CG2 . VAL C 2 45  ? 138.405 177.891 170.477 1.00 74.71  ? 51  VAL E CG2 1 
ATOM 4254 N N   . LEU C 2 46  ? 134.130 178.173 171.010 1.00 77.23  ? 52  LEU E N   1 
ATOM 4255 C CA  . LEU C 2 46  ? 132.834 178.451 171.618 1.00 77.23  ? 52  LEU E CA  1 
ATOM 4256 C C   . LEU C 2 46  ? 131.726 177.549 171.098 1.00 77.23  ? 52  LEU E C   1 
ATOM 4257 O O   . LEU C 2 46  ? 130.695 177.423 171.767 1.00 77.23  ? 52  LEU E O   1 
ATOM 4258 C CB  . LEU C 2 46  ? 132.449 179.916 171.400 1.00 77.23  ? 52  LEU E CB  1 
ATOM 4259 C CG  . LEU C 2 46  ? 132.925 180.922 172.450 1.00 77.23  ? 52  LEU E CG  1 
ATOM 4260 C CD1 . LEU C 2 46  ? 134.437 181.014 172.492 1.00 77.23  ? 52  LEU E CD1 1 
ATOM 4261 C CD2 . LEU C 2 46  ? 132.314 182.285 172.191 1.00 77.23  ? 52  LEU E CD2 1 
ATOM 4262 N N   . ALA C 2 47  ? 131.906 176.917 169.942 1.00 72.85  ? 53  ALA E N   1 
ATOM 4263 C CA  . ALA C 2 47  ? 130.915 175.977 169.440 1.00 72.85  ? 53  ALA E CA  1 
ATOM 4264 C C   . ALA C 2 47  ? 131.275 174.568 169.885 1.00 72.85  ? 53  ALA E C   1 
ATOM 4265 O O   . ALA C 2 47  ? 130.758 173.585 169.346 1.00 72.85  ? 53  ALA E O   1 
ATOM 4266 C CB  . ALA C 2 47  ? 130.818 176.054 167.916 1.00 72.85  ? 53  ALA E CB  1 
ATOM 4267 N N   . ALA C 2 48  ? 132.162 174.463 170.874 1.00 77.77  ? 54  ALA E N   1 
ATOM 4268 C CA  . ALA C 2 48  ? 132.616 173.168 171.360 1.00 77.77  ? 54  ALA E CA  1 
ATOM 4269 C C   . ALA C 2 48  ? 132.527 173.091 172.878 1.00 77.77  ? 54  ALA E C   1 
ATOM 4270 O O   . ALA C 2 48  ? 132.475 171.997 173.448 1.00 77.77  ? 54  ALA E O   1 
ATOM 4271 C CB  . ALA C 2 48  ? 134.050 172.901 170.901 1.00 77.77  ? 54  ALA E CB  1 
ATOM 4272 N N   . CYS C 2 49  ? 132.509 174.248 173.541 1.00 87.67  ? 55  CYS E N   1 
ATOM 4273 C CA  . CYS C 2 49  ? 132.475 174.266 174.997 1.00 87.67  ? 55  CYS E CA  1 
ATOM 4274 C C   . CYS C 2 49  ? 131.064 174.143 175.554 1.00 87.67  ? 55  CYS E C   1 
ATOM 4275 O O   . CYS C 2 49  ? 130.898 173.657 176.677 1.00 87.67  ? 55  CYS E O   1 
ATOM 4276 C CB  . CYS C 2 49  ? 133.123 175.546 175.521 1.00 87.67  ? 55  CYS E CB  1 
ATOM 4277 S SG  . CYS C 2 49  ? 134.765 175.866 174.854 1.00 87.67  ? 55  CYS E SG  1 
ATOM 4278 N N   . SER C 2 50  ? 130.050 174.566 174.802 1.00 94.86  ? 56  SER E N   1 
ATOM 4279 C CA  . SER C 2 50  ? 128.690 174.576 175.327 1.00 94.86  ? 56  SER E CA  1 
ATOM 4280 C C   . SER C 2 50  ? 127.663 174.321 174.233 1.00 94.86  ? 56  SER E C   1 
ATOM 4281 O O   . SER C 2 50  ? 128.012 173.900 173.126 1.00 94.86  ? 56  SER E O   1 
ATOM 4282 C CB  . SER C 2 50  ? 128.402 175.911 176.011 1.00 94.86  ? 56  SER E CB  1 
ATOM 4283 O OG  . SER C 2 50  ? 128.819 176.993 175.198 1.00 94.86  ? 56  SER E OG  1 
ATOM 4284 N N   . SER C 2 51  ? 126.393 174.571 174.540 1.00 97.32  ? 57  SER E N   1 
ATOM 4285 C CA  . SER C 2 51  ? 125.320 174.411 173.563 1.00 97.32  ? 57  SER E CA  1 
ATOM 4286 C C   . SER C 2 51  ? 124.569 175.696 173.246 1.00 97.32  ? 57  SER E C   1 
ATOM 4287 O O   . SER C 2 51  ? 124.003 175.793 172.152 1.00 97.32  ? 57  SER E O   1 
ATOM 4288 C CB  . SER C 2 51  ? 124.316 173.354 174.041 1.00 97.32  ? 57  SER E CB  1 
ATOM 4289 O OG  . SER C 2 51  ? 123.969 173.559 175.399 1.00 97.32  ? 57  SER E OG  1 
ATOM 4290 N N   . TYR C 2 52  ? 124.533 176.681 174.147 1.00 98.38  ? 58  TYR E N   1 
ATOM 4291 C CA  . TYR C 2 52  ? 123.883 177.948 173.827 1.00 98.38  ? 58  TYR E CA  1 
ATOM 4292 C C   . TYR C 2 52  ? 124.566 178.625 172.647 1.00 98.38  ? 58  TYR E C   1 
ATOM 4293 O O   . TYR C 2 52  ? 123.897 179.083 171.716 1.00 98.38  ? 58  TYR E O   1 
ATOM 4294 C CB  . TYR C 2 52  ? 123.877 178.859 175.058 1.00 98.38  ? 58  TYR E CB  1 
ATOM 4295 C CG  . TYR C 2 52  ? 123.355 180.266 174.824 1.00 98.38  ? 58  TYR E CG  1 
ATOM 4296 C CD1 . TYR C 2 52  ? 124.151 181.245 174.241 1.00 98.38  ? 58  TYR E CD1 1 
ATOM 4297 C CD2 . TYR C 2 52  ? 122.060 180.611 175.185 1.00 98.38  ? 58  TYR E CD2 1 
ATOM 4298 C CE1 . TYR C 2 52  ? 123.673 182.522 174.027 1.00 98.38  ? 58  TYR E CE1 1 
ATOM 4299 C CE2 . TYR C 2 52  ? 121.574 181.886 174.975 1.00 98.38  ? 58  TYR E CE2 1 
ATOM 4300 C CZ  . TYR C 2 52  ? 122.385 182.837 174.396 1.00 98.38  ? 58  TYR E CZ  1 
ATOM 4301 O OH  . TYR C 2 52  ? 121.905 184.108 174.184 1.00 98.38  ? 58  TYR E OH  1 
ATOM 4302 N N   . PHE C 2 53  ? 125.897 178.695 172.669 1.00 92.25  ? 59  PHE E N   1 
ATOM 4303 C CA  . PHE C 2 53  ? 126.633 179.253 171.540 1.00 92.25  ? 59  PHE E CA  1 
ATOM 4304 C C   . PHE C 2 53  ? 126.466 178.382 170.302 1.00 92.25  ? 59  PHE E C   1 
ATOM 4305 O O   . PHE C 2 53  ? 126.355 178.885 169.179 1.00 92.25  ? 59  PHE E O   1 
ATOM 4306 C CB  . PHE C 2 53  ? 128.110 179.402 171.902 1.00 92.25  ? 59  PHE E CB  1 
ATOM 4307 C CG  . PHE C 2 53  ? 128.421 180.644 172.681 1.00 92.25  ? 59  PHE E CG  1 
ATOM 4308 C CD1 . PHE C 2 53  ? 127.987 181.880 172.240 1.00 92.25  ? 59  PHE E CD1 1 
ATOM 4309 C CD2 . PHE C 2 53  ? 129.150 180.574 173.856 1.00 92.25  ? 59  PHE E CD2 1 
ATOM 4310 C CE1 . PHE C 2 53  ? 128.274 183.024 172.956 1.00 92.25  ? 59  PHE E CE1 1 
ATOM 4311 C CE2 . PHE C 2 53  ? 129.439 181.714 174.576 1.00 92.25  ? 59  PHE E CE2 1 
ATOM 4312 C CZ  . PHE C 2 53  ? 129.001 182.941 174.126 1.00 92.25  ? 59  PHE E CZ  1 
ATOM 4313 N N   . HIS C 2 54  ? 126.453 177.060 170.498 1.00 90.60  ? 60  HIS E N   1 
ATOM 4314 C CA  . HIS C 2 54  ? 126.360 176.132 169.376 1.00 90.60  ? 60  HIS E CA  1 
ATOM 4315 C C   . HIS C 2 54  ? 125.055 176.307 168.612 1.00 90.60  ? 60  HIS E C   1 
ATOM 4316 O O   . HIS C 2 54  ? 125.041 176.284 167.377 1.00 90.60  ? 60  HIS E O   1 
ATOM 4317 C CB  . HIS C 2 54  ? 126.496 174.696 169.882 1.00 90.60  ? 60  HIS E CB  1 
ATOM 4318 C CG  . HIS C 2 54  ? 126.473 173.666 168.798 1.00 90.60  ? 60  HIS E CG  1 
ATOM 4319 N ND1 . HIS C 2 54  ? 126.869 173.935 167.506 1.00 90.60  ? 60  HIS E ND1 1 
ATOM 4320 C CD2 . HIS C 2 54  ? 126.101 172.364 168.815 1.00 90.60  ? 60  HIS E CD2 1 
ATOM 4321 C CE1 . HIS C 2 54  ? 126.743 172.843 166.773 1.00 90.60  ? 60  HIS E CE1 1 
ATOM 4322 N NE2 . HIS C 2 54  ? 126.277 171.876 167.543 1.00 90.60  ? 60  HIS E NE2 1 
ATOM 4323 N N   . SER C 2 55  ? 123.947 176.482 169.330 1.00 93.58  ? 61  SER E N   1 
ATOM 4324 C CA  . SER C 2 55  ? 122.654 176.658 168.682 1.00 93.58  ? 61  SER E CA  1 
ATOM 4325 C C   . SER C 2 55  ? 122.516 178.003 167.983 1.00 93.58  ? 61  SER E C   1 
ATOM 4326 O O   . SER C 2 55  ? 121.602 178.160 167.165 1.00 93.58  ? 61  SER E O   1 
ATOM 4327 C CB  . SER C 2 55  ? 121.530 176.490 169.706 1.00 93.58  ? 61  SER E CB  1 
ATOM 4328 O OG  . SER C 2 55  ? 121.750 177.306 170.843 1.00 93.58  ? 61  SER E OG  1 
ATOM 4329 N N   . ARG C 2 56  ? 123.384 178.973 168.277 1.00 91.42  ? 62  ARG E N   1 
ATOM 4330 C CA  . ARG C 2 56  ? 123.302 180.294 167.673 1.00 91.42  ? 62  ARG E CA  1 
ATOM 4331 C C   . ARG C 2 56  ? 124.413 180.596 166.678 1.00 91.42  ? 62  ARG E C   1 
ATOM 4332 O O   . ARG C 2 56  ? 124.350 181.637 166.016 1.00 91.42  ? 62  ARG E O   1 
ATOM 4333 C CB  . ARG C 2 56  ? 123.315 181.391 168.752 1.00 91.42  ? 62  ARG E CB  1 
ATOM 4334 C CG  . ARG C 2 56  ? 122.396 181.177 169.950 1.00 91.42  ? 62  ARG E CG  1 
ATOM 4335 C CD  . ARG C 2 56  ? 121.040 180.603 169.570 1.00 91.42  ? 62  ARG E CD  1 
ATOM 4336 N NE  . ARG C 2 56  ? 120.125 180.601 170.705 1.00 91.42  ? 62  ARG E NE  1 
ATOM 4337 C CZ  . ARG C 2 56  ? 118.804 180.592 170.604 1.00 91.42  ? 62  ARG E CZ  1 
ATOM 4338 N NH1 . ARG C 2 56  ? 118.201 180.588 169.427 1.00 91.42  ? 62  ARG E NH1 1 
ATOM 4339 N NH2 . ARG C 2 56  ? 118.068 180.587 171.712 1.00 91.42  ? 62  ARG E NH2 1 
ATOM 4340 N N   . ILE C 2 57  ? 125.421 179.740 166.554 1.00 87.63  ? 63  ILE E N   1 
ATOM 4341 C CA  . ILE C 2 57  ? 126.583 180.028 165.717 1.00 87.63  ? 63  ILE E CA  1 
ATOM 4342 C C   . ILE C 2 57  ? 126.477 179.361 164.349 1.00 87.63  ? 63  ILE E C   1 
ATOM 4343 O O   . ILE C 2 57  ? 126.937 179.907 163.347 1.00 87.63  ? 63  ILE E O   1 
ATOM 4344 C CB  . ILE C 2 57  ? 127.883 179.619 166.447 1.00 87.63  ? 63  ILE E CB  1 
ATOM 4345 C CG1 . ILE C 2 57  ? 129.104 180.081 165.658 1.00 87.63  ? 63  ILE E CG1 1 
ATOM 4346 C CG2 . ILE C 2 57  ? 127.952 178.114 166.640 1.00 87.63  ? 63  ILE E CG2 1 
ATOM 4347 C CD1 . ILE C 2 57  ? 129.221 181.577 165.552 1.00 87.63  ? 63  ILE E CD1 1 
ATOM 4348 N N   . VAL C 2 58  ? 125.860 178.182 164.286 1.00 92.23  ? 64  VAL E N   1 
ATOM 4349 C CA  . VAL C 2 58  ? 125.829 177.384 163.064 1.00 92.23  ? 64  VAL E CA  1 
ATOM 4350 C C   . VAL C 2 58  ? 124.834 177.960 162.067 1.00 92.23  ? 64  VAL E C   1 
ATOM 4351 O O   . VAL C 2 58  ? 123.881 178.652 162.445 1.00 92.23  ? 64  VAL E O   1 
ATOM 4352 C CB  . VAL C 2 58  ? 125.499 175.912 163.371 1.00 92.23  ? 64  VAL E CB  1 
ATOM 4353 C CG1 . VAL C 2 58  ? 126.337 175.416 164.533 1.00 92.23  ? 64  VAL E CG1 1 
ATOM 4354 C CG2 . VAL C 2 58  ? 124.014 175.743 163.668 1.00 92.23  ? 64  VAL E CG2 1 
ATOM 4355 N N   . GLY C 2 59  ? 125.069 177.701 160.783 1.00 104.81 ? 65  GLY E N   1 
ATOM 4356 C CA  . GLY C 2 59  ? 124.121 178.057 159.746 1.00 104.81 ? 65  GLY E CA  1 
ATOM 4357 C C   . GLY C 2 59  ? 124.312 179.457 159.202 1.00 104.81 ? 65  GLY E C   1 
ATOM 4358 O O   . GLY C 2 59  ? 124.247 179.679 157.989 1.00 104.81 ? 65  GLY E O   1 
ATOM 4359 N N   . GLN C 2 60  ? 124.546 180.409 160.100 1.00 103.90 ? 66  GLN E N   1 
ATOM 4360 C CA  . GLN C 2 60  ? 124.713 181.803 159.714 1.00 103.90 ? 66  GLN E CA  1 
ATOM 4361 C C   . GLN C 2 60  ? 126.009 181.994 158.934 1.00 103.90 ? 66  GLN E C   1 
ATOM 4362 O O   . GLN C 2 60  ? 127.026 181.362 159.227 1.00 103.90 ? 66  GLN E O   1 
ATOM 4363 C CB  . GLN C 2 60  ? 124.701 182.684 160.966 1.00 103.90 ? 66  GLN E CB  1 
ATOM 4364 C CG  . GLN C 2 60  ? 125.525 183.944 160.855 1.00 103.90 ? 66  GLN E CG  1 
ATOM 4365 C CD  . GLN C 2 60  ? 125.618 184.692 162.162 1.00 103.90 ? 66  GLN E CD  1 
ATOM 4366 O OE1 . GLN C 2 60  ? 126.707 185.054 162.599 1.00 103.90 ? 66  GLN E OE1 1 
ATOM 4367 N NE2 . GLN C 2 60  ? 124.477 184.923 162.799 1.00 103.90 ? 66  GLN E NE2 1 
ATOM 4368 N N   . ALA C 2 61  ? 125.961 182.875 157.935 1.00 104.62 ? 67  ALA E N   1 
ATOM 4369 C CA  . ALA C 2 61  ? 127.096 183.112 157.049 1.00 104.62 ? 67  ALA E CA  1 
ATOM 4370 C C   . ALA C 2 61  ? 128.289 183.713 157.784 1.00 104.62 ? 67  ALA E C   1 
ATOM 4371 O O   . ALA C 2 61  ? 128.133 184.316 158.852 1.00 104.62 ? 67  ALA E O   1 
ATOM 4372 C CB  . ALA C 2 61  ? 126.682 184.027 155.894 1.00 104.62 ? 67  ALA E CB  1 
ATOM 4373 N N   . ASP C 2 62  ? 129.482 183.543 157.218 1.00 96.50  ? 68  ASP E N   1 
ATOM 4374 C CA  . ASP C 2 62  ? 130.699 184.087 157.808 1.00 96.50  ? 68  ASP E CA  1 
ATOM 4375 C C   . ASP C 2 62  ? 130.704 185.609 157.729 1.00 96.50  ? 68  ASP E C   1 
ATOM 4376 O O   . ASP C 2 62  ? 130.117 186.202 156.820 1.00 96.50  ? 68  ASP E O   1 
ATOM 4377 C CB  . ASP C 2 62  ? 131.925 183.515 157.092 1.00 96.50  ? 68  ASP E CB  1 
ATOM 4378 C CG  . ASP C 2 62  ? 133.237 184.006 157.680 1.00 96.50  ? 68  ASP E CG  1 
ATOM 4379 O OD1 . ASP C 2 62  ? 133.600 185.178 157.445 1.00 96.50  ? 68  ASP E OD1 1 
ATOM 4380 O OD2 . ASP C 2 62  ? 133.912 183.212 158.372 1.00 96.50  ? 68  ASP E OD2 1 
ATOM 4381 N N   . GLY C 2 63  ? 131.365 186.240 158.688 1.00 96.85  ? 69  GLY E N   1 
ATOM 4382 C CA  . GLY C 2 63  ? 131.539 187.677 158.670 1.00 96.85  ? 69  GLY E CA  1 
ATOM 4383 C C   . GLY C 2 63  ? 131.565 188.238 160.078 1.00 96.85  ? 69  GLY E C   1 
ATOM 4384 O O   . GLY C 2 63  ? 131.707 187.505 161.052 1.00 96.85  ? 69  GLY E O   1 
ATOM 4385 N N   . GLU C 2 64  ? 131.435 189.561 160.149 1.00 107.76 ? 70  GLU E N   1 
ATOM 4386 C CA  . GLU C 2 64  ? 131.401 190.257 161.428 1.00 107.76 ? 70  GLU E CA  1 
ATOM 4387 C C   . GLU C 2 64  ? 130.208 189.789 162.252 1.00 107.76 ? 70  GLU E C   1 
ATOM 4388 O O   . GLU C 2 64  ? 129.109 189.591 161.726 1.00 107.76 ? 70  GLU E O   1 
ATOM 4389 C CB  . GLU C 2 64  ? 131.340 191.767 161.197 1.00 107.76 ? 70  GLU E CB  1 
ATOM 4390 C CG  . GLU C 2 64  ? 131.383 192.611 162.456 1.00 107.76 ? 70  GLU E CG  1 
ATOM 4391 C CD  . GLU C 2 64  ? 130.024 193.168 162.818 1.00 107.76 ? 70  GLU E CD  1 
ATOM 4392 O OE1 . GLU C 2 64  ? 129.468 193.954 162.022 1.00 107.76 ? 70  GLU E OE1 1 
ATOM 4393 O OE2 . GLU C 2 64  ? 129.510 192.818 163.898 1.00 107.76 ? 70  GLU E OE2 1 
ATOM 4394 N N   . LEU C 2 65  ? 130.429 189.605 163.554 1.00 100.74 ? 71  LEU E N   1 
ATOM 4395 C CA  . LEU C 2 65  ? 129.431 188.972 164.404 1.00 100.74 ? 71  LEU E CA  1 
ATOM 4396 C C   . LEU C 2 65  ? 129.348 189.648 165.765 1.00 100.74 ? 71  LEU E C   1 
ATOM 4397 O O   . LEU C 2 65  ? 130.370 189.962 166.381 1.00 100.74 ? 71  LEU E O   1 
ATOM 4398 C CB  . LEU C 2 65  ? 129.740 187.482 164.590 1.00 100.74 ? 71  LEU E CB  1 
ATOM 4399 C CG  . LEU C 2 65  ? 128.665 186.653 165.296 1.00 100.74 ? 71  LEU E CG  1 
ATOM 4400 C CD1 . LEU C 2 65  ? 127.277 187.052 164.830 1.00 100.74 ? 71  LEU E CD1 1 
ATOM 4401 C CD2 . LEU C 2 65  ? 128.900 185.167 165.081 1.00 100.74 ? 71  LEU E CD2 1 
ATOM 4402 N N   . ASN C 2 66  ? 128.115 189.866 166.217 1.00 104.73 ? 72  ASN E N   1 
ATOM 4403 C CA  . ASN C 2 66  ? 127.795 190.130 167.612 1.00 104.73 ? 72  ASN E CA  1 
ATOM 4404 C C   . ASN C 2 66  ? 126.825 189.054 168.070 1.00 104.73 ? 72  ASN E C   1 
ATOM 4405 O O   . ASN C 2 66  ? 125.788 188.842 167.434 1.00 104.73 ? 72  ASN E O   1 
ATOM 4406 C CB  . ASN C 2 66  ? 127.172 191.516 167.812 1.00 104.73 ? 72  ASN E CB  1 
ATOM 4407 C CG  . ASN C 2 66  ? 127.769 192.565 166.900 1.00 104.73 ? 72  ASN E CG  1 
ATOM 4408 O OD1 . ASN C 2 66  ? 128.932 192.478 166.513 1.00 104.73 ? 72  ASN E OD1 1 
ATOM 4409 N ND2 . ASN C 2 66  ? 126.969 193.563 166.544 1.00 104.73 ? 72  ASN E ND2 1 
ATOM 4410 N N   . ILE C 2 67  ? 127.163 188.371 169.159 1.00 106.00 ? 73  ILE E N   1 
ATOM 4411 C CA  . ILE C 2 67  ? 126.338 187.286 169.679 1.00 106.00 ? 73  ILE E CA  1 
ATOM 4412 C C   . ILE C 2 67  ? 125.970 187.685 171.107 1.00 106.00 ? 73  ILE E C   1 
ATOM 4413 O O   . ILE C 2 67  ? 125.980 186.867 172.034 1.00 106.00 ? 73  ILE E O   1 
ATOM 4414 C CB  . ILE C 2 67  ? 127.068 185.929 169.570 1.00 106.00 ? 73  ILE E CB  1 
ATOM 4415 C CG1 . ILE C 2 67  ? 126.229 184.770 170.126 1.00 106.00 ? 73  ILE E CG1 1 
ATOM 4416 C CG2 . ILE C 2 67  ? 128.427 185.997 170.243 1.00 106.00 ? 73  ILE E CG2 1 
ATOM 4417 C CD1 . ILE C 2 67  ? 124.851 184.667 169.510 1.00 106.00 ? 73  ILE E CD1 1 
ATOM 4418 N N   . THR C 2 68  ? 125.689 188.977 171.287 1.00 101.81 ? 74  THR E N   1 
ATOM 4419 C CA  . THR C 2 68  ? 125.433 189.608 172.579 1.00 101.81 ? 74  THR E CA  1 
ATOM 4420 C C   . THR C 2 68  ? 124.592 188.758 173.526 1.00 101.81 ? 74  THR E C   1 
ATOM 4421 O O   . THR C 2 68  ? 123.486 188.335 173.179 1.00 101.81 ? 74  THR E O   1 
ATOM 4422 C CB  . THR C 2 68  ? 124.731 190.953 172.363 1.00 101.81 ? 74  THR E CB  1 
ATOM 4423 O OG1 . THR C 2 68  ? 125.672 191.915 171.878 1.00 101.81 ? 74  THR E OG1 1 
ATOM 4424 C CG2 . THR C 2 68  ? 124.128 191.460 173.664 1.00 101.81 ? 74  THR E CG2 1 
ATOM 4425 N N   . LEU C 2 69  ? 125.116 188.502 174.719 1.00 102.18 ? 75  LEU E N   1 
ATOM 4426 C CA  . LEU C 2 69  ? 124.332 187.874 175.777 1.00 102.18 ? 75  LEU E CA  1 
ATOM 4427 C C   . LEU C 2 69  ? 123.500 188.959 176.446 1.00 102.18 ? 75  LEU E C   1 
ATOM 4428 O O   . LEU C 2 69  ? 124.064 189.821 177.131 1.00 102.18 ? 75  LEU E O   1 
ATOM 4429 C CB  . LEU C 2 69  ? 125.247 187.188 176.786 1.00 102.18 ? 75  LEU E CB  1 
ATOM 4430 C CG  . LEU C 2 69  ? 125.649 185.729 176.536 1.00 102.18 ? 75  LEU E CG  1 
ATOM 4431 C CD1 . LEU C 2 69  ? 126.005 185.473 175.080 1.00 102.18 ? 75  LEU E CD1 1 
ATOM 4432 C CD2 . LEU C 2 69  ? 126.809 185.336 177.436 1.00 102.18 ? 75  LEU E CD2 1 
ATOM 4433 N N   . PRO C 2 70  ? 122.172 188.965 176.277 1.00 108.15 ? 76  PRO E N   1 
ATOM 4434 C CA  . PRO C 2 70  ? 121.411 190.209 176.478 1.00 108.15 ? 76  PRO E CA  1 
ATOM 4435 C C   . PRO C 2 70  ? 121.495 190.835 177.865 1.00 108.15 ? 76  PRO E C   1 
ATOM 4436 O O   . PRO C 2 70  ? 122.021 191.945 177.994 1.00 108.15 ? 76  PRO E O   1 
ATOM 4437 C CB  . PRO C 2 70  ? 119.969 189.786 176.159 1.00 108.15 ? 76  PRO E CB  1 
ATOM 4438 C CG  . PRO C 2 70  ? 119.957 188.296 176.273 1.00 108.15 ? 76  PRO E CG  1 
ATOM 4439 C CD  . PRO C 2 70  ? 121.315 187.847 175.852 1.00 108.15 ? 76  PRO E CD  1 
ATOM 4440 N N   . GLU C 2 71  ? 120.995 190.166 178.905 1.00 107.06 ? 77  GLU E N   1 
ATOM 4441 C CA  . GLU C 2 71  ? 121.067 190.768 180.233 1.00 107.06 ? 77  GLU E CA  1 
ATOM 4442 C C   . GLU C 2 71  ? 121.363 189.767 181.343 1.00 107.06 ? 77  GLU E C   1 
ATOM 4443 O O   . GLU C 2 71  ? 121.885 190.142 182.398 1.00 107.06 ? 77  GLU E O   1 
ATOM 4444 C CB  . GLU C 2 71  ? 119.763 191.515 180.539 1.00 107.06 ? 77  GLU E CB  1 
ATOM 4445 C CG  . GLU C 2 71  ? 118.674 190.704 181.249 1.00 107.06 ? 77  GLU E CG  1 
ATOM 4446 C CD  . GLU C 2 71  ? 118.119 189.545 180.428 1.00 107.06 ? 77  GLU E CD  1 
ATOM 4447 O OE1 . GLU C 2 71  ? 118.673 189.214 179.359 1.00 107.06 ? 77  GLU E OE1 1 
ATOM 4448 O OE2 . GLU C 2 71  ? 117.110 188.953 180.866 1.00 107.06 ? 77  GLU E OE2 1 
ATOM 4449 N N   . GLU C 2 72  ? 121.033 188.497 181.118 1.00 110.28 ? 78  GLU E N   1 
ATOM 4450 C CA  . GLU C 2 72  ? 120.957 187.523 182.201 1.00 110.28 ? 78  GLU E CA  1 
ATOM 4451 C C   . GLU C 2 72  ? 122.321 187.233 182.816 1.00 110.28 ? 78  GLU E C   1 
ATOM 4452 O O   . GLU C 2 72  ? 122.439 187.110 184.039 1.00 110.28 ? 78  GLU E O   1 
ATOM 4453 C CB  . GLU C 2 72  ? 120.300 186.228 181.707 1.00 110.28 ? 78  GLU E CB  1 
ATOM 4454 C CG  . GLU C 2 72  ? 121.019 185.500 180.574 1.00 110.28 ? 78  GLU E CG  1 
ATOM 4455 C CD  . GLU C 2 72  ? 120.851 186.159 179.212 1.00 110.28 ? 78  GLU E CD  1 
ATOM 4456 O OE1 . GLU C 2 72  ? 120.678 185.423 178.218 1.00 110.28 ? 78  GLU E OE1 1 
ATOM 4457 O OE2 . GLU C 2 72  ? 120.909 187.404 179.125 1.00 110.28 ? 78  GLU E OE2 1 
ATOM 4458 N N   . VAL C 2 73  ? 123.356 187.118 181.983 1.00 112.21 ? 79  VAL E N   1 
ATOM 4459 C CA  . VAL C 2 73  ? 124.685 186.842 182.504 1.00 112.21 ? 79  VAL E CA  1 
ATOM 4460 C C   . VAL C 2 73  ? 125.298 188.122 183.046 1.00 112.21 ? 79  VAL E C   1 
ATOM 4461 O O   . VAL C 2 73  ? 124.929 189.232 182.645 1.00 112.21 ? 79  VAL E O   1 
ATOM 4462 C CB  . VAL C 2 73  ? 125.572 186.212 181.415 1.00 112.21 ? 79  VAL E CB  1 
ATOM 4463 C CG1 . VAL C 2 73  ? 124.847 185.055 180.745 1.00 112.21 ? 79  VAL E CG1 1 
ATOM 4464 C CG2 . VAL C 2 73  ? 125.985 187.260 180.394 1.00 112.21 ? 79  VAL E CG2 1 
ATOM 4465 N N   . THR C 2 74  ? 126.229 187.967 183.980 1.00 113.01 ? 80  THR E N   1 
ATOM 4466 C CA  . THR C 2 74  ? 127.022 189.071 184.487 1.00 113.01 ? 80  THR E CA  1 
ATOM 4467 C C   . THR C 2 74  ? 128.356 189.113 183.746 1.00 113.01 ? 80  THR E C   1 
ATOM 4468 O O   . THR C 2 74  ? 128.582 188.381 182.782 1.00 113.01 ? 80  THR E O   1 
ATOM 4469 C CB  . THR C 2 74  ? 127.230 188.935 185.996 1.00 113.01 ? 80  THR E CB  1 
ATOM 4470 O OG1 . THR C 2 74  ? 128.241 187.952 186.253 1.00 113.01 ? 80  THR E OG1 1 
ATOM 4471 C CG2 . THR C 2 74  ? 125.936 188.510 186.673 1.00 113.01 ? 80  THR E CG2 1 
ATOM 4472 N N   . VAL C 2 75  ? 129.246 189.992 184.195 1.00 104.76 ? 81  VAL E N   1 
ATOM 4473 C CA  . VAL C 2 75  ? 130.616 190.029 183.702 1.00 104.76 ? 81  VAL E CA  1 
ATOM 4474 C C   . VAL C 2 75  ? 131.572 189.346 184.670 1.00 104.76 ? 81  VAL E C   1 
ATOM 4475 O O   . VAL C 2 75  ? 132.499 188.654 184.247 1.00 104.76 ? 81  VAL E O   1 
ATOM 4476 C CB  . VAL C 2 75  ? 131.052 191.483 183.422 1.00 104.76 ? 81  VAL E CB  1 
ATOM 4477 C CG1 . VAL C 2 75  ? 130.501 191.950 182.088 1.00 104.76 ? 81  VAL E CG1 1 
ATOM 4478 C CG2 . VAL C 2 75  ? 130.592 192.401 184.542 1.00 104.76 ? 81  VAL E CG2 1 
ATOM 4479 N N   . LYS C 2 76  ? 131.353 189.538 185.973 1.00 108.84 ? 82  LYS E N   1 
ATOM 4480 C CA  . LYS C 2 76  ? 132.138 188.828 186.975 1.00 108.84 ? 82  LYS E CA  1 
ATOM 4481 C C   . LYS C 2 76  ? 131.958 187.323 186.837 1.00 108.84 ? 82  LYS E C   1 
ATOM 4482 O O   . LYS C 2 76  ? 132.863 186.546 187.164 1.00 108.84 ? 82  LYS E O   1 
ATOM 4483 C CB  . LYS C 2 76  ? 131.736 189.295 188.375 1.00 108.84 ? 82  LYS E CB  1 
ATOM 4484 C CG  . LYS C 2 76  ? 132.331 190.639 188.777 1.00 108.84 ? 82  LYS E CG  1 
ATOM 4485 C CD  . LYS C 2 76  ? 132.393 190.824 190.292 1.00 108.84 ? 82  LYS E CD  1 
ATOM 4486 C CE  . LYS C 2 76  ? 131.231 190.153 191.013 1.00 108.84 ? 82  LYS E CE  1 
ATOM 4487 N NZ  . LYS C 2 76  ? 129.904 190.678 190.580 1.00 108.84 ? 82  LYS E NZ  1 
ATOM 4488 N N   . GLY C 2 77  ? 130.793 186.895 186.361 1.00 108.27 ? 83  GLY E N   1 
ATOM 4489 C CA  . GLY C 2 77  ? 130.541 185.491 186.115 1.00 108.27 ? 83  GLY E CA  1 
ATOM 4490 C C   . GLY C 2 77  ? 130.831 185.074 184.689 1.00 108.27 ? 83  GLY E C   1 
ATOM 4491 O O   . GLY C 2 77  ? 130.724 183.892 184.351 1.00 108.27 ? 83  GLY E O   1 
ATOM 4492 N N   . PHE C 2 78  ? 131.199 186.033 183.839 1.00 98.64  ? 84  PHE E N   1 
ATOM 4493 C CA  . PHE C 2 78  ? 131.510 185.720 182.449 1.00 98.64  ? 84  PHE E CA  1 
ATOM 4494 C C   . PHE C 2 78  ? 133.005 185.594 182.204 1.00 98.64  ? 84  PHE E C   1 
ATOM 4495 O O   . PHE C 2 78  ? 133.435 184.705 181.462 1.00 98.64  ? 84  PHE E O   1 
ATOM 4496 C CB  . PHE C 2 78  ? 130.935 186.787 181.517 1.00 98.64  ? 84  PHE E CB  1 
ATOM 4497 C CG  . PHE C 2 78  ? 131.043 186.437 180.059 1.00 98.64  ? 84  PHE E CG  1 
ATOM 4498 C CD1 . PHE C 2 78  ? 130.921 185.124 179.637 1.00 98.64  ? 84  PHE E CD1 1 
ATOM 4499 C CD2 . PHE C 2 78  ? 131.280 187.419 179.113 1.00 98.64  ? 84  PHE E CD2 1 
ATOM 4500 C CE1 . PHE C 2 78  ? 131.022 184.798 178.301 1.00 98.64  ? 84  PHE E CE1 1 
ATOM 4501 C CE2 . PHE C 2 78  ? 131.384 187.098 177.774 1.00 98.64  ? 84  PHE E CE2 1 
ATOM 4502 C CZ  . PHE C 2 78  ? 131.255 185.786 177.368 1.00 98.64  ? 84  PHE E CZ  1 
ATOM 4503 N N   . GLU C 2 79  ? 133.804 186.474 182.804 1.00 92.53  ? 85  GLU E N   1 
ATOM 4504 C CA  . GLU C 2 79  ? 135.251 186.435 182.600 1.00 92.53  ? 85  GLU E CA  1 
ATOM 4505 C C   . GLU C 2 79  ? 135.874 185.080 182.919 1.00 92.53  ? 85  GLU E C   1 
ATOM 4506 O O   . GLU C 2 79  ? 136.689 184.602 182.113 1.00 92.53  ? 85  GLU E O   1 
ATOM 4507 C CB  . GLU C 2 79  ? 135.913 187.553 183.418 1.00 92.53  ? 85  GLU E CB  1 
ATOM 4508 C CG  . GLU C 2 79  ? 137.423 187.660 183.237 1.00 92.53  ? 85  GLU E CG  1 
ATOM 4509 C CD  . GLU C 2 79  ? 137.849 187.869 181.794 1.00 92.53  ? 85  GLU E CD  1 
ATOM 4510 O OE1 . GLU C 2 79  ? 139.019 187.572 181.476 1.00 92.53  ? 85  GLU E OE1 1 
ATOM 4511 O OE2 . GLU C 2 79  ? 137.031 188.353 180.984 1.00 92.53  ? 85  GLU E OE2 1 
ATOM 4512 N N   . PRO C 2 80  ? 135.561 184.416 184.039 1.00 89.78  ? 86  PRO E N   1 
ATOM 4513 C CA  . PRO C 2 80  ? 136.140 183.083 184.269 1.00 89.78  ? 86  PRO E CA  1 
ATOM 4514 C C   . PRO C 2 80  ? 135.668 182.024 183.286 1.00 89.78  ? 86  PRO E C   1 
ATOM 4515 O O   . PRO C 2 80  ? 136.404 181.057 183.051 1.00 89.78  ? 86  PRO E O   1 
ATOM 4516 C CB  . PRO C 2 80  ? 135.696 182.751 185.701 1.00 89.78  ? 86  PRO E CB  1 
ATOM 4517 C CG  . PRO C 2 80  ? 135.380 184.072 186.316 1.00 89.78  ? 86  PRO E CG  1 
ATOM 4518 C CD  . PRO C 2 80  ? 134.777 184.858 185.204 1.00 89.78  ? 86  PRO E CD  1 
ATOM 4519 N N   . LEU C 2 81  ? 134.476 182.167 182.702 1.00 87.78  ? 87  LEU E N   1 
ATOM 4520 C CA  . LEU C 2 81  ? 133.947 181.131 181.821 1.00 87.78  ? 87  LEU E CA  1 
ATOM 4521 C C   . LEU C 2 81  ? 134.761 180.946 180.549 1.00 87.78  ? 87  LEU E C   1 
ATOM 4522 O O   . LEU C 2 81  ? 135.128 179.810 180.230 1.00 87.78  ? 87  LEU E O   1 
ATOM 4523 C CB  . LEU C 2 81  ? 132.495 181.432 181.447 1.00 87.78  ? 87  LEU E CB  1 
ATOM 4524 C CG  . LEU C 2 81  ? 131.412 180.767 182.295 1.00 87.78  ? 87  LEU E CG  1 
ATOM 4525 C CD1 . LEU C 2 81  ? 131.266 179.313 181.885 1.00 87.78  ? 87  LEU E CD1 1 
ATOM 4526 C CD2 . LEU C 2 81  ? 131.724 180.872 183.772 1.00 87.78  ? 87  LEU E CD2 1 
ATOM 4527 N N   . ILE C 2 82  ? 135.055 182.022 179.814 1.00 78.84  ? 88  ILE E N   1 
ATOM 4528 C CA  . ILE C 2 82  ? 135.872 181.890 178.611 1.00 78.84  ? 88  ILE E CA  1 
ATOM 4529 C C   . ILE C 2 82  ? 137.314 181.542 178.946 1.00 78.84  ? 88  ILE E C   1 
ATOM 4530 O O   . ILE C 2 82  ? 137.982 180.868 178.144 1.00 78.84  ? 88  ILE E O   1 
ATOM 4531 C CB  . ILE C 2 82  ? 135.786 183.166 177.749 1.00 78.84  ? 88  ILE E CB  1 
ATOM 4532 C CG1 . ILE C 2 82  ? 136.783 184.224 178.216 1.00 78.84  ? 88  ILE E CG1 1 
ATOM 4533 C CG2 . ILE C 2 82  ? 134.377 183.724 177.775 1.00 78.84  ? 88  ILE E CG2 1 
ATOM 4534 C CD1 . ILE C 2 82  ? 136.937 185.374 177.249 1.00 78.84  ? 88  ILE E CD1 1 
ATOM 4535 N N   . GLN C 2 83  ? 137.809 181.953 180.115 1.00 78.68  ? 89  GLN E N   1 
ATOM 4536 C CA  . GLN C 2 83  ? 139.116 181.499 180.568 1.00 78.68  ? 89  GLN E CA  1 
ATOM 4537 C C   . GLN C 2 83  ? 139.146 179.989 180.744 1.00 78.68  ? 89  GLN E C   1 
ATOM 4538 O O   . GLN C 2 83  ? 140.103 179.337 180.313 1.00 78.68  ? 89  GLN E O   1 
ATOM 4539 C CB  . GLN C 2 83  ? 139.484 182.190 181.880 1.00 78.68  ? 89  GLN E CB  1 
ATOM 4540 C CG  . GLN C 2 83  ? 139.803 183.665 181.733 1.00 78.68  ? 89  GLN E CG  1 
ATOM 4541 C CD  . GLN C 2 83  ? 141.277 183.957 181.897 1.00 78.68  ? 89  GLN E CD  1 
ATOM 4542 O OE1 . GLN C 2 83  ? 142.125 183.126 181.575 1.00 78.68  ? 89  GLN E OE1 1 
ATOM 4543 N NE2 . GLN C 2 83  ? 141.592 185.144 182.401 1.00 78.68  ? 89  GLN E NE2 1 
ATOM 4544 N N   . PHE C 2 84  ? 138.107 179.421 181.357 1.00 77.08  ? 90  PHE E N   1 
ATOM 4545 C CA  . PHE C 2 84  ? 138.006 177.970 181.441 1.00 77.08  ? 90  PHE E CA  1 
ATOM 4546 C C   . PHE C 2 84  ? 137.851 177.341 180.066 1.00 77.08  ? 90  PHE E C   1 
ATOM 4547 O O   . PHE C 2 84  ? 138.372 176.247 179.823 1.00 77.08  ? 90  PHE E O   1 
ATOM 4548 C CB  . PHE C 2 84  ? 136.834 177.565 182.332 1.00 77.08  ? 90  PHE E CB  1 
ATOM 4549 C CG  . PHE C 2 84  ? 136.753 176.089 182.583 1.00 77.08  ? 90  PHE E CG  1 
ATOM 4550 C CD1 . PHE C 2 84  ? 137.743 175.439 183.297 1.00 77.08  ? 90  PHE E CD1 1 
ATOM 4551 C CD2 . PHE C 2 84  ? 135.692 175.349 182.093 1.00 77.08  ? 90  PHE E CD2 1 
ATOM 4552 C CE1 . PHE C 2 84  ? 137.673 174.080 183.524 1.00 77.08  ? 90  PHE E CE1 1 
ATOM 4553 C CE2 . PHE C 2 84  ? 135.617 173.990 182.317 1.00 77.08  ? 90  PHE E CE2 1 
ATOM 4554 C CZ  . PHE C 2 84  ? 136.608 173.355 183.034 1.00 77.08  ? 90  PHE E CZ  1 
ATOM 4555 N N   . ALA C 2 85  ? 137.135 178.007 179.162 1.00 69.52  ? 91  ALA E N   1 
ATOM 4556 C CA  . ALA C 2 85  ? 136.930 177.452 177.830 1.00 69.52  ? 91  ALA E CA  1 
ATOM 4557 C C   . ALA C 2 85  ? 138.243 177.343 177.066 1.00 69.52  ? 91  ALA E C   1 
ATOM 4558 O O   . ALA C 2 85  ? 138.469 176.362 176.349 1.00 69.52  ? 91  ALA E O   1 
ATOM 4559 C CB  . ALA C 2 85  ? 135.929 178.307 177.058 1.00 69.52  ? 91  ALA E CB  1 
ATOM 4560 N N   . TYR C 2 86  ? 139.117 178.336 177.205 1.00 69.37  ? 92  TYR E N   1 
ATOM 4561 C CA  . TYR C 2 86  ? 140.331 178.406 176.403 1.00 69.37  ? 92  TYR E CA  1 
ATOM 4562 C C   . TYR C 2 86  ? 141.567 177.852 177.105 1.00 69.37  ? 92  TYR E C   1 
ATOM 4563 O O   . TYR C 2 86  ? 142.577 177.607 176.438 1.00 69.37  ? 92  TYR E O   1 
ATOM 4564 C CB  . TYR C 2 86  ? 140.594 179.849 175.973 1.00 69.37  ? 92  TYR E CB  1 
ATOM 4565 C CG  . TYR C 2 86  ? 139.784 180.283 174.777 1.00 69.37  ? 92  TYR E CG  1 
ATOM 4566 C CD1 . TYR C 2 86  ? 138.506 180.794 174.930 1.00 69.37  ? 92  TYR E CD1 1 
ATOM 4567 C CD2 . TYR C 2 86  ? 140.298 180.179 173.495 1.00 69.37  ? 92  TYR E CD2 1 
ATOM 4568 C CE1 . TYR C 2 86  ? 137.764 181.192 173.840 1.00 69.37  ? 92  TYR E CE1 1 
ATOM 4569 C CE2 . TYR C 2 86  ? 139.564 180.574 172.400 1.00 69.37  ? 92  TYR E CE2 1 
ATOM 4570 C CZ  . TYR C 2 86  ? 138.298 181.078 172.577 1.00 69.37  ? 92  TYR E CZ  1 
ATOM 4571 O OH  . TYR C 2 86  ? 137.563 181.473 171.484 1.00 69.37  ? 92  TYR E OH  1 
ATOM 4572 N N   . THR C 2 87  ? 141.526 177.650 178.422 1.00 76.14  ? 93  THR E N   1 
ATOM 4573 C CA  . THR C 2 87  ? 142.743 177.267 179.129 1.00 76.14  ? 93  THR E CA  1 
ATOM 4574 C C   . THR C 2 87  ? 142.489 176.079 180.051 1.00 76.14  ? 93  THR E C   1 
ATOM 4575 O O   . THR C 2 87  ? 143.423 175.363 180.427 1.00 76.14  ? 93  THR E O   1 
ATOM 4576 C CB  . THR C 2 87  ? 143.288 178.472 179.905 1.00 76.14  ? 93  THR E CB  1 
ATOM 4577 O OG1 . THR C 2 87  ? 143.661 179.499 178.979 1.00 76.14  ? 93  THR E OG1 1 
ATOM 4578 C CG2 . THR C 2 87  ? 144.525 178.098 180.703 1.00 76.14  ? 93  THR E CG2 1 
ATOM 4579 N N   . ALA C 2 88  ? 141.219 175.859 180.399 1.00 77.57  ? 94  ALA E N   1 
ATOM 4580 C CA  . ALA C 2 88  ? 140.776 174.757 181.251 1.00 77.57  ? 94  ALA E CA  1 
ATOM 4581 C C   . ALA C 2 88  ? 141.204 174.945 182.700 1.00 77.57  ? 94  ALA E C   1 
ATOM 4582 O O   . ALA C 2 88  ? 141.553 173.975 183.379 1.00 77.57  ? 94  ALA E O   1 
ATOM 4583 C CB  . ALA C 2 88  ? 141.275 173.409 180.722 1.00 77.57  ? 94  ALA E CB  1 
ATOM 4584 N N   . LYS C 2 89  ? 141.179 176.185 183.183 1.00 85.86  ? 95  LYS E N   1 
ATOM 4585 C CA  . LYS C 2 89  ? 141.323 176.450 184.608 1.00 85.86  ? 95  LYS E CA  1 
ATOM 4586 C C   . LYS C 2 89  ? 140.257 177.457 185.006 1.00 85.86  ? 95  LYS E C   1 
ATOM 4587 O O   . LYS C 2 89  ? 139.802 178.241 184.168 1.00 85.86  ? 95  LYS E O   1 
ATOM 4588 C CB  . LYS C 2 89  ? 142.716 176.985 184.961 1.00 85.86  ? 95  LYS E CB  1 
ATOM 4589 C CG  . LYS C 2 89  ? 142.879 178.487 184.786 1.00 85.86  ? 95  LYS E CG  1 
ATOM 4590 C CD  . LYS C 2 89  ? 144.205 178.844 184.144 1.00 85.86  ? 95  LYS E CD  1 
ATOM 4591 C CE  . LYS C 2 89  ? 144.258 180.320 183.781 1.00 85.86  ? 95  LYS E CE  1 
ATOM 4592 N NZ  . LYS C 2 89  ? 143.484 180.631 182.548 1.00 85.86  ? 95  LYS E NZ  1 
ATOM 4593 N N   . LEU C 2 90  ? 139.853 177.425 186.269 1.00 97.80  ? 96  LEU E N   1 
ATOM 4594 C CA  . LEU C 2 90  ? 138.837 178.338 186.763 1.00 97.80  ? 96  LEU E CA  1 
ATOM 4595 C C   . LEU C 2 90  ? 139.407 179.223 187.867 1.00 97.80  ? 96  LEU E C   1 
ATOM 4596 O O   . LEU C 2 90  ? 140.404 178.898 188.513 1.00 97.80  ? 96  LEU E O   1 
ATOM 4597 C CB  . LEU C 2 90  ? 137.626 177.560 187.275 1.00 97.80  ? 96  LEU E CB  1 
ATOM 4598 C CG  . LEU C 2 90  ? 136.277 177.807 186.600 1.00 97.80  ? 96  LEU E CG  1 
ATOM 4599 C CD1 . LEU C 2 90  ? 135.163 177.126 187.374 1.00 97.80  ? 96  LEU E CD1 1 
ATOM 4600 C CD2 . LEU C 2 90  ? 136.008 179.290 186.475 1.00 97.80  ? 96  LEU E CD2 1 
ATOM 4601 N N   . ILE C 2 91  ? 138.756 180.363 188.079 1.00 106.00 ? 97  ILE E N   1 
ATOM 4602 C CA  . ILE C 2 91  ? 139.120 181.253 189.173 1.00 106.00 ? 97  ILE E CA  1 
ATOM 4603 C C   . ILE C 2 91  ? 137.862 181.538 189.980 1.00 106.00 ? 97  ILE E C   1 
ATOM 4604 O O   . ILE C 2 91  ? 136.999 182.317 189.560 1.00 106.00 ? 97  ILE E O   1 
ATOM 4605 C CB  . ILE C 2 91  ? 139.773 182.549 188.657 1.00 106.00 ? 97  ILE E CB  1 
ATOM 4606 C CG1 . ILE C 2 91  ? 141.196 182.264 188.167 1.00 106.00 ? 97  ILE E CG1 1 
ATOM 4607 C CG2 . ILE C 2 91  ? 139.790 183.617 189.746 1.00 106.00 ? 97  ILE E CG2 1 
ATOM 4608 C CD1 . ILE C 2 91  ? 142.272 182.460 189.218 1.00 106.00 ? 97  ILE E CD1 1 
ATOM 4609 N N   . LEU C 2 92  ? 137.737 180.887 191.129 1.00 117.91 ? 98  LEU E N   1 
ATOM 4610 C CA  . LEU C 2 92  ? 136.562 181.036 191.972 1.00 117.91 ? 98  LEU E CA  1 
ATOM 4611 C C   . LEU C 2 92  ? 136.941 181.639 193.317 1.00 117.91 ? 98  LEU E C   1 
ATOM 4612 O O   . LEU C 2 92  ? 137.970 181.300 193.907 1.00 117.91 ? 98  LEU E O   1 
ATOM 4613 C CB  . LEU C 2 92  ? 135.871 179.688 192.183 1.00 117.91 ? 98  LEU E CB  1 
ATOM 4614 C CG  . LEU C 2 92  ? 135.189 179.077 190.959 1.00 117.91 ? 98  LEU E CG  1 
ATOM 4615 C CD1 . LEU C 2 92  ? 134.697 177.674 191.270 1.00 117.91 ? 98  LEU E CD1 1 
ATOM 4616 C CD2 . LEU C 2 92  ? 134.043 179.958 190.488 1.00 117.91 ? 98  LEU E CD2 1 
ATOM 4617 N N   . SER C 2 93  ? 136.091 182.542 193.797 1.00 122.39 ? 99  SER E N   1 
ATOM 4618 C CA  . SER C 2 93  ? 136.262 183.169 195.097 1.00 122.39 ? 99  SER E CA  1 
ATOM 4619 C C   . SER C 2 93  ? 134.893 183.288 195.752 1.00 122.39 ? 99  SER E C   1 
ATOM 4620 O O   . SER C 2 93  ? 133.856 183.166 195.093 1.00 122.39 ? 99  SER E O   1 
ATOM 4621 C CB  . SER C 2 93  ? 136.947 184.534 194.969 1.00 122.39 ? 99  SER E CB  1 
ATOM 4622 O OG  . SER C 2 93  ? 135.996 185.560 194.750 1.00 122.39 ? 99  SER E OG  1 
ATOM 4623 N N   . LYS C 2 94  ? 134.889 183.552 197.057 1.00 123.04 ? 100 LYS E N   1 
ATOM 4624 C CA  . LYS C 2 94  ? 133.659 183.599 197.849 1.00 123.04 ? 100 LYS E CA  1 
ATOM 4625 C C   . LYS C 2 94  ? 132.724 184.715 197.401 1.00 123.04 ? 100 LYS E C   1 
ATOM 4626 O O   . LYS C 2 94  ? 131.576 184.797 197.845 1.00 123.04 ? 100 LYS E O   1 
ATOM 4627 C CB  . LYS C 2 94  ? 134.015 183.746 199.325 1.00 123.04 ? 100 LYS E CB  1 
ATOM 4628 C CG  . LYS C 2 94  ? 132.887 183.411 200.289 1.00 123.04 ? 100 LYS E CG  1 
ATOM 4629 C CD  . LYS C 2 94  ? 133.338 183.551 201.732 1.00 123.04 ? 100 LYS E CD  1 
ATOM 4630 C CE  . LYS C 2 94  ? 132.176 183.371 202.694 1.00 123.04 ? 100 LYS E CE  1 
ATOM 4631 N NZ  . LYS C 2 94  ? 132.592 183.577 204.109 1.00 123.04 ? 100 LYS E NZ  1 
ATOM 4632 N N   . GLU C 2 95  ? 133.185 185.580 196.500 1.00 119.86 ? 101 GLU E N   1 
ATOM 4633 C CA  . GLU C 2 95  ? 132.352 186.645 195.964 1.00 119.86 ? 101 GLU E CA  1 
ATOM 4634 C C   . GLU C 2 95  ? 132.161 186.441 194.468 1.00 119.86 ? 101 GLU E C   1 
ATOM 4635 O O   . GLU C 2 95  ? 131.845 187.386 193.738 1.00 119.86 ? 101 GLU E O   1 
ATOM 4636 C CB  . GLU C 2 95  ? 132.975 188.016 196.242 1.00 119.86 ? 101 GLU E CB  1 
ATOM 4637 C CG  . GLU C 2 95  ? 134.462 188.125 195.910 1.00 119.86 ? 101 GLU E CG  1 
ATOM 4638 C CD  . GLU C 2 95  ? 135.369 187.642 197.029 1.00 119.86 ? 101 GLU E CD  1 
ATOM 4639 O OE1 . GLU C 2 95  ? 135.029 186.642 197.693 1.00 119.86 ? 101 GLU E OE1 1 
ATOM 4640 O OE2 . GLU C 2 95  ? 136.429 188.265 197.244 1.00 119.86 ? 101 GLU E OE2 1 
ATOM 4641 N N   . ASN C 2 96  ? 132.357 185.207 194.003 1.00 117.50 ? 102 ASN E N   1 
ATOM 4642 C CA  . ASN C 2 96  ? 132.312 184.914 192.577 1.00 117.50 ? 102 ASN E CA  1 
ATOM 4643 C C   . ASN C 2 96  ? 131.468 183.682 192.271 1.00 117.50 ? 102 ASN E C   1 
ATOM 4644 O O   . ASN C 2 96  ? 130.995 183.517 191.144 1.00 117.50 ? 102 ASN E O   1 
ATOM 4645 C CB  . ASN C 2 96  ? 133.730 184.720 192.037 1.00 117.50 ? 102 ASN E CB  1 
ATOM 4646 C CG  . ASN C 2 96  ? 133.964 185.460 190.738 1.00 117.50 ? 102 ASN E CG  1 
ATOM 4647 O OD1 . ASN C 2 96  ? 133.929 186.689 190.696 1.00 117.50 ? 102 ASN E OD1 1 
ATOM 4648 N ND2 . ASN C 2 96  ? 134.208 184.714 189.668 1.00 117.50 ? 102 ASN E ND2 1 
ATOM 4649 N N   . VAL C 2 97  ? 131.271 182.819 193.265 1.00 119.54 ? 103 VAL E N   1 
ATOM 4650 C CA  . VAL C 2 97  ? 130.700 181.492 193.052 1.00 119.54 ? 103 VAL E CA  1 
ATOM 4651 C C   . VAL C 2 97  ? 129.301 181.563 192.455 1.00 119.54 ? 103 VAL E C   1 
ATOM 4652 O O   . VAL C 2 97  ? 128.977 180.817 191.525 1.00 119.54 ? 103 VAL E O   1 
ATOM 4653 C CB  . VAL C 2 97  ? 130.680 180.694 194.367 1.00 119.54 ? 103 VAL E CB  1 
ATOM 4654 C CG1 . VAL C 2 97  ? 130.118 179.300 194.135 1.00 119.54 ? 103 VAL E CG1 1 
ATOM 4655 C CG2 . VAL C 2 97  ? 132.072 180.622 194.952 1.00 119.54 ? 103 VAL E CG2 1 
ATOM 4656 N N   . ASP C 2 98  ? 128.460 182.451 192.991 1.00 118.56 ? 104 ASP E N   1 
ATOM 4657 C CA  . ASP C 2 98  ? 127.051 182.457 192.608 1.00 118.56 ? 104 ASP E CA  1 
ATOM 4658 C C   . ASP C 2 98  ? 126.868 182.774 191.128 1.00 118.56 ? 104 ASP E C   1 
ATOM 4659 O O   . ASP C 2 98  ? 126.134 182.072 190.423 1.00 118.56 ? 104 ASP E O   1 
ATOM 4660 C CB  . ASP C 2 98  ? 126.279 183.458 193.467 1.00 118.56 ? 104 ASP E CB  1 
ATOM 4661 C CG  . ASP C 2 98  ? 124.946 182.914 193.936 1.00 118.56 ? 104 ASP E CG  1 
ATOM 4662 O OD1 . ASP C 2 98  ? 124.604 181.773 193.560 1.00 118.56 ? 104 ASP E OD1 1 
ATOM 4663 O OD2 . ASP C 2 98  ? 124.240 183.626 194.680 1.00 118.56 ? 104 ASP E OD2 1 
ATOM 4664 N N   . GLU C 2 99  ? 127.526 183.826 190.638 1.00 119.42 ? 105 GLU E N   1 
ATOM 4665 C CA  . GLU C 2 99  ? 127.353 184.219 189.242 1.00 119.42 ? 105 GLU E CA  1 
ATOM 4666 C C   . GLU C 2 99  ? 127.947 183.189 188.288 1.00 119.42 ? 105 GLU E C   1 
ATOM 4667 O O   . GLU C 2 99  ? 127.364 182.906 187.235 1.00 119.42 ? 105 GLU E O   1 
ATOM 4668 C CB  . GLU C 2 99  ? 127.956 185.605 189.005 1.00 119.42 ? 105 GLU E CB  1 
ATOM 4669 C CG  . GLU C 2 99  ? 129.384 185.778 189.496 1.00 119.42 ? 105 GLU E CG  1 
ATOM 4670 C CD  . GLU C 2 99  ? 129.454 186.141 190.970 1.00 119.42 ? 105 GLU E CD  1 
ATOM 4671 O OE1 . GLU C 2 99  ? 128.963 185.353 191.806 1.00 119.42 ? 105 GLU E OE1 1 
ATOM 4672 O OE2 . GLU C 2 99  ? 130.002 187.215 191.293 1.00 119.42 ? 105 GLU E OE2 1 
ATOM 4673 N N   . VAL C 2 100 ? 129.099 182.612 188.635 1.00 115.59 ? 106 VAL E N   1 
ATOM 4674 C CA  . VAL C 2 100 ? 129.683 181.571 187.793 1.00 115.59 ? 106 VAL E CA  1 
ATOM 4675 C C   . VAL C 2 100 ? 128.763 180.358 187.726 1.00 115.59 ? 106 VAL E C   1 
ATOM 4676 O O   . VAL C 2 100 ? 128.540 179.789 186.651 1.00 115.59 ? 106 VAL E O   1 
ATOM 4677 C CB  . VAL C 2 100 ? 131.087 181.190 188.293 1.00 115.59 ? 106 VAL E CB  1 
ATOM 4678 C CG1 . VAL C 2 100 ? 131.746 180.235 187.321 1.00 115.59 ? 106 VAL E CG1 1 
ATOM 4679 C CG2 . VAL C 2 100 ? 131.945 182.432 188.434 1.00 115.59 ? 106 VAL E CG2 1 
ATOM 4680 N N   . CYS C 2 101 ? 128.220 179.940 188.872 1.00 115.47 ? 107 CYS E N   1 
ATOM 4681 C CA  . CYS C 2 101 ? 127.296 178.813 188.881 1.00 115.47 ? 107 CYS E CA  1 
ATOM 4682 C C   . CYS C 2 101 ? 126.019 179.118 188.112 1.00 115.47 ? 107 CYS E C   1 
ATOM 4683 O O   . CYS C 2 101 ? 125.459 178.217 187.479 1.00 115.47 ? 107 CYS E O   1 
ATOM 4684 C CB  . CYS C 2 101 ? 126.958 178.416 190.318 1.00 115.47 ? 107 CYS E CB  1 
ATOM 4685 S SG  . CYS C 2 101 ? 125.997 176.892 190.457 1.00 115.47 ? 107 CYS E SG  1 
ATOM 4686 N N   . LYS C 2 102 ? 125.546 180.364 188.160 1.00 111.10 ? 108 LYS E N   1 
ATOM 4687 C CA  . LYS C 2 102 ? 124.398 180.753 187.349 1.00 111.10 ? 108 LYS E CA  1 
ATOM 4688 C C   . LYS C 2 102 ? 124.726 180.658 185.865 1.00 111.10 ? 108 LYS E C   1 
ATOM 4689 O O   . LYS C 2 102 ? 123.906 180.203 185.060 1.00 111.10 ? 108 LYS E O   1 
ATOM 4690 C CB  . LYS C 2 102 ? 123.958 182.170 187.718 1.00 111.10 ? 108 LYS E CB  1 
ATOM 4691 C CG  . LYS C 2 102 ? 122.573 182.543 187.222 1.00 111.10 ? 108 LYS E CG  1 
ATOM 4692 C CD  . LYS C 2 102 ? 121.513 181.654 187.848 1.00 111.10 ? 108 LYS E CD  1 
ATOM 4693 C CE  . LYS C 2 102 ? 120.975 182.258 189.135 1.00 111.10 ? 108 LYS E CE  1 
ATOM 4694 N NZ  . LYS C 2 102 ? 119.986 181.364 189.796 1.00 111.10 ? 108 LYS E NZ  1 
ATOM 4695 N N   . CYS C 2 103 ? 125.930 181.089 185.485 1.00 110.07 ? 109 CYS E N   1 
ATOM 4696 C CA  . CYS C 2 103 ? 126.354 181.034 184.092 1.00 110.07 ? 109 CYS E CA  1 
ATOM 4697 C C   . CYS C 2 103 ? 126.499 179.612 183.567 1.00 110.07 ? 109 CYS E C   1 
ATOM 4698 O O   . CYS C 2 103 ? 126.104 179.354 182.425 1.00 110.07 ? 109 CYS E O   1 
ATOM 4699 C CB  . CYS C 2 103 ? 127.676 181.783 183.919 1.00 110.07 ? 109 CYS E CB  1 
ATOM 4700 S SG  . CYS C 2 103 ? 127.494 183.560 183.651 1.00 110.07 ? 109 CYS E SG  1 
ATOM 4701 N N   . VAL C 2 104 ? 127.067 178.695 184.352 1.00 106.91 ? 110 VAL E N   1 
ATOM 4702 C CA  . VAL C 2 104 ? 127.213 177.327 183.858 1.00 106.91 ? 110 VAL E CA  1 
ATOM 4703 C C   . VAL C 2 104 ? 125.860 176.660 183.636 1.00 106.91 ? 110 VAL E C   1 
ATOM 4704 O O   . VAL C 2 104 ? 125.643 176.035 182.591 1.00 106.91 ? 110 VAL E O   1 
ATOM 4705 C CB  . VAL C 2 104 ? 128.090 176.470 184.785 1.00 106.91 ? 110 VAL E CB  1 
ATOM 4706 C CG1 . VAL C 2 104 ? 128.609 175.276 184.023 1.00 106.91 ? 110 VAL E CG1 1 
ATOM 4707 C CG2 . VAL C 2 104 ? 129.267 177.264 185.284 1.00 106.91 ? 110 VAL E CG2 1 
ATOM 4708 N N   . GLU C 2 105 ? 124.935 176.770 184.590 1.00 107.98 ? 111 GLU E N   1 
ATOM 4709 C CA  . GLU C 2 105 ? 123.634 176.134 184.430 1.00 107.98 ? 111 GLU E CA  1 
ATOM 4710 C C   . GLU C 2 105 ? 122.810 176.756 183.312 1.00 107.98 ? 111 GLU E C   1 
ATOM 4711 O O   . GLU C 2 105 ? 121.831 176.143 182.871 1.00 107.98 ? 111 GLU E O   1 
ATOM 4712 C CB  . GLU C 2 105 ? 122.842 176.193 185.737 1.00 107.98 ? 111 GLU E CB  1 
ATOM 4713 C CG  . GLU C 2 105 ? 122.067 177.482 185.936 1.00 107.98 ? 111 GLU E CG  1 
ATOM 4714 C CD  . GLU C 2 105 ? 120.981 177.348 186.984 1.00 107.98 ? 111 GLU E CD  1 
ATOM 4715 O OE1 . GLU C 2 105 ? 119.903 176.809 186.655 1.00 107.98 ? 111 GLU E OE1 1 
ATOM 4716 O OE2 . GLU C 2 105 ? 121.205 177.777 188.135 1.00 107.98 ? 111 GLU E OE2 1 
ATOM 4717 N N   . PHE C 2 106 ? 123.179 177.948 182.847 1.00 102.17 ? 112 PHE E N   1 
ATOM 4718 C CA  . PHE C 2 106 ? 122.516 178.591 181.720 1.00 102.17 ? 112 PHE E CA  1 
ATOM 4719 C C   . PHE C 2 106 ? 123.147 178.169 180.397 1.00 102.17 ? 112 PHE E C   1 
ATOM 4720 O O   . PHE C 2 106 ? 122.473 177.595 179.536 1.00 102.17 ? 112 PHE E O   1 
ATOM 4721 C CB  . PHE C 2 106 ? 122.578 180.117 181.883 1.00 102.17 ? 112 PHE E CB  1 
ATOM 4722 C CG  . PHE C 2 106 ? 122.114 180.880 180.674 1.00 102.17 ? 112 PHE E CG  1 
ATOM 4723 C CD1 . PHE C 2 106 ? 121.039 180.437 179.920 1.00 102.17 ? 112 PHE E CD1 1 
ATOM 4724 C CD2 . PHE C 2 106 ? 122.775 182.026 180.275 1.00 102.17 ? 112 PHE E CD2 1 
ATOM 4725 C CE1 . PHE C 2 106 ? 120.623 181.135 178.805 1.00 102.17 ? 112 PHE E CE1 1 
ATOM 4726 C CE2 . PHE C 2 106 ? 122.365 182.724 179.160 1.00 102.17 ? 112 PHE E CE2 1 
ATOM 4727 C CZ  . PHE C 2 106 ? 121.287 182.280 178.426 1.00 102.17 ? 112 PHE E CZ  1 
ATOM 4728 N N   . LEU C 2 107 ? 124.441 178.442 180.223 1.00 102.81 ? 113 LEU E N   1 
ATOM 4729 C CA  . LEU C 2 107 ? 125.115 178.133 178.969 1.00 102.81 ? 113 LEU E CA  1 
ATOM 4730 C C   . LEU C 2 107 ? 125.338 176.642 178.767 1.00 102.81 ? 113 LEU E C   1 
ATOM 4731 O O   . LEU C 2 107 ? 125.668 176.234 177.648 1.00 102.81 ? 113 LEU E O   1 
ATOM 4732 C CB  . LEU C 2 107 ? 126.454 178.869 178.900 1.00 102.81 ? 113 LEU E CB  1 
ATOM 4733 C CG  . LEU C 2 107 ? 126.369 180.396 178.880 1.00 102.81 ? 113 LEU E CG  1 
ATOM 4734 C CD1 . LEU C 2 107 ? 127.754 181.016 178.960 1.00 102.81 ? 113 LEU E CD1 1 
ATOM 4735 C CD2 . LEU C 2 107 ? 125.633 180.875 177.641 1.00 102.81 ? 113 LEU E CD2 1 
ATOM 4736 N N   . SER C 2 108 ? 125.163 175.828 179.809 1.00 103.40 ? 114 SER E N   1 
ATOM 4737 C CA  . SER C 2 108 ? 125.358 174.379 179.733 1.00 103.40 ? 114 SER E CA  1 
ATOM 4738 C C   . SER C 2 108 ? 126.758 174.018 179.244 1.00 103.40 ? 114 SER E C   1 
ATOM 4739 O O   . SER C 2 108 ? 126.919 173.176 178.359 1.00 103.40 ? 114 SER E O   1 
ATOM 4740 C CB  . SER C 2 108 ? 124.299 173.720 178.845 1.00 103.40 ? 114 SER E CB  1 
ATOM 4741 O OG  . SER C 2 108 ? 124.694 173.743 177.486 1.00 103.40 ? 114 SER E OG  1 
ATOM 4742 N N   . VAL C 2 109 ? 127.777 174.659 179.812 1.00 95.79  ? 115 VAL E N   1 
ATOM 4743 C CA  . VAL C 2 109 ? 129.158 174.358 179.452 1.00 95.79  ? 115 VAL E CA  1 
ATOM 4744 C C   . VAL C 2 109 ? 129.490 172.946 179.917 1.00 95.79  ? 115 VAL E C   1 
ATOM 4745 O O   . VAL C 2 109 ? 129.151 172.552 181.038 1.00 95.79  ? 115 VAL E O   1 
ATOM 4746 C CB  . VAL C 2 109 ? 130.118 175.386 180.060 1.00 95.79  ? 115 VAL E CB  1 
ATOM 4747 C CG1 . VAL C 2 109 ? 131.555 175.038 179.716 1.00 95.79  ? 115 VAL E CG1 1 
ATOM 4748 C CG2 . VAL C 2 109 ? 129.771 176.782 179.574 1.00 95.79  ? 115 VAL E CG2 1 
ATOM 4749 N N   . HIS C 2 110 ? 130.137 172.172 179.050 1.00 93.68  ? 116 HIS E N   1 
ATOM 4750 C CA  . HIS C 2 110 ? 130.483 170.802 179.393 1.00 93.68  ? 116 HIS E CA  1 
ATOM 4751 C C   . HIS C 2 110 ? 131.857 170.741 180.063 1.00 93.68  ? 116 HIS E C   1 
ATOM 4752 O O   . HIS C 2 110 ? 132.536 171.752 180.261 1.00 93.68  ? 116 HIS E O   1 
ATOM 4753 C CB  . HIS C 2 110 ? 130.456 169.913 178.151 1.00 93.68  ? 116 HIS E CB  1 
ATOM 4754 C CG  . HIS C 2 110 ? 129.306 170.188 177.235 1.00 93.68  ? 116 HIS E CG  1 
ATOM 4755 N ND1 . HIS C 2 110 ? 129.415 170.999 176.127 1.00 93.68  ? 116 HIS E ND1 1 
ATOM 4756 C CD2 . HIS C 2 110 ? 128.024 169.756 177.261 1.00 93.68  ? 116 HIS E CD2 1 
ATOM 4757 C CE1 . HIS C 2 110 ? 128.249 171.057 175.510 1.00 93.68  ? 116 HIS E CE1 1 
ATOM 4758 N NE2 . HIS C 2 110 ? 127.387 170.312 176.178 1.00 93.68  ? 116 HIS E NE2 1 
ATOM 4759 N N   . ASN C 2 111 ? 132.260 169.516 180.409 1.00 87.72  ? 117 ASN E N   1 
ATOM 4760 C CA  . ASN C 2 111 ? 133.527 169.213 181.076 1.00 87.72  ? 117 ASN E CA  1 
ATOM 4761 C C   . ASN C 2 111 ? 133.737 170.017 182.353 1.00 87.72  ? 117 ASN E C   1 
ATOM 4762 O O   . ASN C 2 111 ? 134.872 170.168 182.813 1.00 87.72  ? 117 ASN E O   1 
ATOM 4763 C CB  . ASN C 2 111 ? 134.725 169.405 180.140 1.00 87.72  ? 117 ASN E CB  1 
ATOM 4764 C CG  . ASN C 2 111 ? 134.411 169.050 178.707 1.00 87.72  ? 117 ASN E CG  1 
ATOM 4765 O OD1 . ASN C 2 111 ? 133.597 169.694 178.050 1.00 87.72  ? 117 ASN E OD1 1 
ATOM 4766 N ND2 . ASN C 2 111 ? 135.052 168.001 178.217 1.00 87.72  ? 117 ASN E ND2 1 
ATOM 4767 N N   . ILE C 2 112 ? 132.666 170.536 182.942 1.00 99.68  ? 118 ILE E N   1 
ATOM 4768 C CA  . ILE C 2 112 ? 132.722 171.211 184.232 1.00 99.68  ? 118 ILE E CA  1 
ATOM 4769 C C   . ILE C 2 112 ? 131.677 170.564 185.133 1.00 99.68  ? 118 ILE E C   1 
ATOM 4770 O O   . ILE C 2 112 ? 130.490 170.519 184.788 1.00 99.68  ? 118 ILE E O   1 
ATOM 4771 C CB  . ILE C 2 112 ? 132.505 172.727 184.111 1.00 99.68  ? 118 ILE E CB  1 
ATOM 4772 C CG1 . ILE C 2 112 ? 132.502 173.389 185.492 1.00 99.68  ? 118 ILE E CG1 1 
ATOM 4773 C CG2 . ILE C 2 112 ? 131.263 173.047 183.300 1.00 99.68  ? 118 ILE E CG2 1 
ATOM 4774 C CD1 . ILE C 2 112 ? 132.788 174.874 185.457 1.00 99.68  ? 118 ILE E CD1 1 
ATOM 4775 N N   . GLU C 2 113 ? 132.121 170.038 186.269 1.00 119.87 ? 119 GLU E N   1 
ATOM 4776 C CA  . GLU C 2 113 ? 131.237 169.341 187.185 1.00 119.87 ? 119 GLU E CA  1 
ATOM 4777 C C   . GLU C 2 113 ? 130.740 170.308 188.261 1.00 119.87 ? 119 GLU E C   1 
ATOM 4778 O O   . GLU C 2 113 ? 131.318 171.373 188.494 1.00 119.87 ? 119 GLU E O   1 
ATOM 4779 C CB  . GLU C 2 113 ? 131.967 168.132 187.784 1.00 119.87 ? 119 GLU E CB  1 
ATOM 4780 C CG  . GLU C 2 113 ? 131.254 167.386 188.907 1.00 119.87 ? 119 GLU E CG  1 
ATOM 4781 C CD  . GLU C 2 113 ? 130.290 166.336 188.391 1.00 119.87 ? 119 GLU E CD  1 
ATOM 4782 O OE1 . GLU C 2 113 ? 129.126 166.322 188.845 1.00 119.87 ? 119 GLU E OE1 1 
ATOM 4783 O OE2 . GLU C 2 113 ? 130.694 165.523 187.534 1.00 119.87 ? 119 GLU E OE2 1 
ATOM 4784 N N   . GLU C 2 114 ? 129.647 169.923 188.927 1.00 135.98 ? 120 GLU E N   1 
ATOM 4785 C CA  . GLU C 2 114 ? 129.073 170.759 189.977 1.00 135.98 ? 120 GLU E CA  1 
ATOM 4786 C C   . GLU C 2 114 ? 129.962 170.815 191.215 1.00 135.98 ? 120 GLU E C   1 
ATOM 4787 O O   . GLU C 2 114 ? 129.556 171.375 192.239 1.00 135.98 ? 120 GLU E O   1 
ATOM 4788 C CB  . GLU C 2 114 ? 127.670 170.252 190.327 1.00 135.98 ? 120 GLU E CB  1 
ATOM 4789 C CG  . GLU C 2 114 ? 127.625 169.003 191.208 1.00 135.98 ? 120 GLU E CG  1 
ATOM 4790 C CD  . GLU C 2 114 ? 127.557 169.318 192.692 1.00 135.98 ? 120 GLU E CD  1 
ATOM 4791 O OE1 . GLU C 2 114 ? 126.826 170.257 193.069 1.00 135.98 ? 120 GLU E OE1 1 
ATOM 4792 O OE2 . GLU C 2 114 ? 128.239 168.628 193.479 1.00 135.98 ? 120 GLU E OE2 1 
ATOM 4793 N N   . SER C 2 115 ? 131.179 170.271 191.133 1.00 131.27 ? 121 SER E N   1 
ATOM 4794 C CA  . SER C 2 115 ? 132.119 170.225 192.249 1.00 131.27 ? 121 SER E CA  1 
ATOM 4795 C C   . SER C 2 115 ? 132.366 171.595 192.873 1.00 131.27 ? 121 SER E C   1 
ATOM 4796 O O   . SER C 2 115 ? 132.900 171.685 193.984 1.00 131.27 ? 121 SER E O   1 
ATOM 4797 C CB  . SER C 2 115 ? 133.447 169.618 191.791 1.00 131.27 ? 121 SER E CB  1 
ATOM 4798 O OG  . SER C 2 115 ? 133.449 168.212 191.965 1.00 131.27 ? 121 SER E OG  1 
ATOM 4799 N N   . CYS C 2 116 ? 131.987 172.668 192.176 1.00 140.93 ? 122 CYS E N   1 
ATOM 4800 C CA  . CYS C 2 116 ? 132.008 174.012 192.752 1.00 140.93 ? 122 CYS E CA  1 
ATOM 4801 C C   . CYS C 2 116 ? 130.785 174.207 193.654 1.00 140.93 ? 122 CYS E C   1 
ATOM 4802 O O   . CYS C 2 116 ? 129.979 175.123 193.489 1.00 140.93 ? 122 CYS E O   1 
ATOM 4803 C CB  . CYS C 2 116 ? 132.061 175.063 191.651 1.00 140.93 ? 122 CYS E CB  1 
ATOM 4804 S SG  . CYS C 2 116 ? 131.007 174.714 190.223 1.00 140.93 ? 122 CYS E SG  1 
ATOM 4805 N N   . PHE C 2 117 ? 130.666 173.309 194.632 1.00 146.89 ? 123 PHE E N   1 
ATOM 4806 C CA  . PHE C 2 117 ? 129.487 173.206 195.481 1.00 146.89 ? 123 PHE E CA  1 
ATOM 4807 C C   . PHE C 2 117 ? 129.759 173.472 196.953 1.00 146.89 ? 123 PHE E C   1 
ATOM 4808 O O   . PHE C 2 117 ? 129.068 174.296 197.553 1.00 146.89 ? 123 PHE E O   1 
ATOM 4809 C CB  . PHE C 2 117 ? 128.862 171.811 195.336 1.00 146.89 ? 123 PHE E CB  1 
ATOM 4810 C CG  . PHE C 2 117 ? 127.733 171.543 196.289 1.00 146.89 ? 123 PHE E CG  1 
ATOM 4811 C CD1 . PHE C 2 117 ? 126.471 172.063 196.056 1.00 146.89 ? 123 PHE E CD1 1 
ATOM 4812 C CD2 . PHE C 2 117 ? 127.929 170.751 197.409 1.00 146.89 ? 123 PHE E CD2 1 
ATOM 4813 C CE1 . PHE C 2 117 ? 125.429 171.811 196.930 1.00 146.89 ? 123 PHE E CE1 1 
ATOM 4814 C CE2 . PHE C 2 117 ? 126.893 170.495 198.286 1.00 146.89 ? 123 PHE E CE2 1 
ATOM 4815 C CZ  . PHE C 2 117 ? 125.641 171.026 198.046 1.00 146.89 ? 123 PHE E CZ  1 
ATOM 4816 N N   . GLN C 2 118 ? 130.743 172.799 197.547 1.00 146.77 ? 124 GLN E N   1 
ATOM 4817 C CA  . GLN C 2 118 ? 130.991 172.924 198.977 1.00 146.77 ? 124 GLN E CA  1 
ATOM 4818 C C   . GLN C 2 118 ? 132.435 173.324 199.254 1.00 146.77 ? 124 GLN E C   1 
ATOM 4819 O O   . GLN C 2 118 ? 132.872 173.337 200.410 1.00 146.77 ? 124 GLN E O   1 
ATOM 4820 C CB  . GLN C 2 118 ? 130.651 171.611 199.691 1.00 146.77 ? 124 GLN E CB  1 
ATOM 4821 C CG  . GLN C 2 118 ? 131.715 170.515 199.587 1.00 146.77 ? 124 GLN E CG  1 
ATOM 4822 C CD  . GLN C 2 118 ? 131.925 170.000 198.171 1.00 146.77 ? 124 GLN E CD  1 
ATOM 4823 O OE1 . GLN C 2 118 ? 131.201 170.366 197.244 1.00 146.77 ? 124 GLN E OE1 1 
ATOM 4824 N NE2 . GLN C 2 118 ? 132.923 169.140 198.001 1.00 146.77 ? 124 GLN E NE2 1 
ATOM 4825 N N   . PHE C 2 119 ? 133.179 173.658 198.200 1.00 144.32 ? 125 PHE E N   1 
ATOM 4826 C CA  . PHE C 2 119 ? 134.573 174.061 198.337 1.00 144.32 ? 125 PHE E CA  1 
ATOM 4827 C C   . PHE C 2 119 ? 134.688 175.347 199.145 1.00 144.32 ? 125 PHE E C   1 
ATOM 4828 O O   . PHE C 2 119 ? 135.724 175.609 199.766 1.00 144.32 ? 125 PHE E O   1 
ATOM 4829 C CB  . PHE C 2 119 ? 135.220 174.254 196.964 1.00 144.32 ? 125 PHE E CB  1 
ATOM 4830 C CG  . PHE C 2 119 ? 134.681 175.431 196.198 1.00 144.32 ? 125 PHE E CG  1 
ATOM 4831 C CD1 . PHE C 2 119 ? 133.396 175.419 195.683 1.00 144.32 ? 125 PHE E CD1 1 
ATOM 4832 C CD2 . PHE C 2 119 ? 135.462 176.556 196.002 1.00 144.32 ? 125 PHE E CD2 1 
ATOM 4833 C CE1 . PHE C 2 119 ? 132.907 176.505 194.984 1.00 144.32 ? 125 PHE E CE1 1 
ATOM 4834 C CE2 . PHE C 2 119 ? 134.979 177.641 195.302 1.00 144.32 ? 125 PHE E CE2 1 
ATOM 4835 C CZ  . PHE C 2 119 ? 133.701 177.614 194.792 1.00 144.32 ? 125 PHE E CZ  1 
ATOM 4836 N N   . LEU C 2 120 ? 133.628 176.155 199.136 1.00 144.06 ? 126 LEU E N   1 
ATOM 4837 C CA  . LEU C 2 120 ? 133.618 177.439 199.826 1.00 144.06 ? 126 LEU E CA  1 
ATOM 4838 C C   . LEU C 2 120 ? 133.778 177.272 201.331 1.00 144.06 ? 126 LEU E C   1 
ATOM 4839 O O   . LEU C 2 120 ? 133.699 176.153 201.850 1.00 144.06 ? 126 LEU E O   1 
ATOM 4840 C CB  . LEU C 2 120 ? 132.323 178.195 199.525 1.00 144.06 ? 126 LEU E CB  1 
ATOM 4841 C CG  . LEU C 2 120 ? 132.329 179.145 198.329 1.00 144.06 ? 126 LEU E CG  1 
ATOM 4842 C CD1 . LEU C 2 120 ? 131.095 180.034 198.363 1.00 144.06 ? 126 LEU E CD1 1 
ATOM 4843 C CD2 . LEU C 2 120 ? 133.602 179.976 198.305 1.00 144.06 ? 126 LEU E CD2 1 
ATOM 4844 N N   . LYS C 2 121 ? 133.982 178.385 202.033 1.00 147.05 ? 127 LYS E N   1 
ATOM 4845 C CA  . LYS C 2 121 ? 134.151 178.399 203.486 1.00 147.05 ? 127 LYS E CA  1 
ATOM 4846 C C   . LYS C 2 121 ? 135.236 177.428 203.943 1.00 147.05 ? 127 LYS E C   1 
ATOM 4847 O O   . LYS C 2 121 ? 136.298 177.334 203.326 1.00 147.05 ? 127 LYS E O   1 
ATOM 4848 C CB  . LYS C 2 121 ? 132.826 178.078 204.192 1.00 147.05 ? 127 LYS E CB  1 
ATOM 4849 C CG  . LYS C 2 121 ? 131.577 178.533 203.445 1.00 147.05 ? 127 LYS E CG  1 
ATOM 4850 C CD  . LYS C 2 121 ? 130.381 177.658 203.786 1.00 147.05 ? 127 LYS E CD  1 
ATOM 4851 C CE  . LYS C 2 121 ? 130.533 176.255 203.222 1.00 147.05 ? 127 LYS E CE  1 
ATOM 4852 N NZ  . LYS C 2 121 ? 130.857 176.263 201.771 1.00 147.05 ? 127 LYS E NZ  1 
ATOM 4853 N N   . PRO D 3 2   ? 201.220 189.420 193.013 1.00 121.12 ? 2   PRO B N   1 
ATOM 4854 C CA  . PRO D 3 2   ? 200.077 189.131 193.885 1.00 121.12 ? 2   PRO B CA  1 
ATOM 4855 C C   . PRO D 3 2   ? 200.447 189.153 195.367 1.00 121.12 ? 2   PRO B C   1 
ATOM 4856 O O   . PRO D 3 2   ? 201.216 188.307 195.824 1.00 121.12 ? 2   PRO B O   1 
ATOM 4857 C CB  . PRO D 3 2   ? 199.649 187.727 193.448 1.00 121.12 ? 2   PRO B CB  1 
ATOM 4858 C CG  . PRO D 3 2   ? 200.880 187.120 192.871 1.00 121.12 ? 2   PRO B CG  1 
ATOM 4859 C CD  . PRO D 3 2   ? 201.617 188.248 192.213 1.00 121.12 ? 2   PRO B CD  1 
ATOM 4860 N N   . SER D 3 3   ? 199.899 190.114 196.109 1.00 119.78 ? 3   SER B N   1 
ATOM 4861 C CA  . SER D 3 3   ? 200.210 190.249 197.527 1.00 119.78 ? 3   SER B CA  1 
ATOM 4862 C C   . SER D 3 3   ? 198.995 190.801 198.256 1.00 119.78 ? 3   SER B C   1 
ATOM 4863 O O   . SER D 3 3   ? 198.468 191.852 197.877 1.00 119.78 ? 3   SER B O   1 
ATOM 4864 C CB  . SER D 3 3   ? 201.422 191.163 197.739 1.00 119.78 ? 3   SER B CB  1 
ATOM 4865 O OG  . SER D 3 3   ? 201.693 191.340 199.118 1.00 119.78 ? 3   SER B OG  1 
ATOM 4866 N N   . ILE D 3 4   ? 198.555 190.091 199.292 1.00 112.92 ? 4   ILE B N   1 
ATOM 4867 C CA  . ILE D 3 4   ? 197.459 190.530 200.150 1.00 112.92 ? 4   ILE B CA  1 
ATOM 4868 C C   . ILE D 3 4   ? 197.815 190.182 201.589 1.00 112.92 ? 4   ILE B C   1 
ATOM 4869 O O   . ILE D 3 4   ? 198.301 189.080 201.864 1.00 112.92 ? 4   ILE B O   1 
ATOM 4870 C CB  . ILE D 3 4   ? 196.118 189.886 199.746 1.00 112.92 ? 4   ILE B CB  1 
ATOM 4871 C CG1 . ILE D 3 4   ? 195.043 190.175 200.796 1.00 112.92 ? 4   ILE B CG1 1 
ATOM 4872 C CG2 . ILE D 3 4   ? 196.280 188.389 199.523 1.00 112.92 ? 4   ILE B CG2 1 
ATOM 4873 C CD1 . ILE D 3 4   ? 193.693 189.592 200.463 1.00 112.92 ? 4   ILE B CD1 1 
ATOM 4874 N N   . LYS D 3 5   ? 197.583 191.119 202.506 1.00 112.71 ? 5   LYS B N   1 
ATOM 4875 C CA  . LYS D 3 5   ? 197.891 190.931 203.920 1.00 112.71 ? 5   LYS B CA  1 
ATOM 4876 C C   . LYS D 3 5   ? 196.588 190.762 204.690 1.00 112.71 ? 5   LYS B C   1 
ATOM 4877 O O   . LYS D 3 5   ? 195.660 191.563 204.537 1.00 112.71 ? 5   LYS B O   1 
ATOM 4878 C CB  . LYS D 3 5   ? 198.701 192.103 204.470 1.00 112.71 ? 5   LYS B CB  1 
ATOM 4879 C CG  . LYS D 3 5   ? 200.005 192.360 203.738 1.00 112.71 ? 5   LYS B CG  1 
ATOM 4880 C CD  . LYS D 3 5   ? 200.739 193.552 204.328 1.00 112.71 ? 5   LYS B CD  1 
ATOM 4881 C CE  . LYS D 3 5   ? 202.055 193.799 203.611 1.00 112.71 ? 5   LYS B CE  1 
ATOM 4882 N NZ  . LYS D 3 5   ? 202.745 195.014 204.124 1.00 112.71 ? 5   LYS B NZ  1 
ATOM 4883 N N   . LEU D 3 6   ? 196.522 189.721 205.511 1.00 100.72 ? 6   LEU B N   1 
ATOM 4884 C CA  . LEU D 3 6   ? 195.380 189.464 206.373 1.00 100.72 ? 6   LEU B CA  1 
ATOM 4885 C C   . LEU D 3 6   ? 195.750 189.745 207.823 1.00 100.72 ? 6   LEU B C   1 
ATOM 4886 O O   . LEU D 3 6   ? 196.905 189.596 208.229 1.00 100.72 ? 6   LEU B O   1 
ATOM 4887 C CB  . LEU D 3 6   ? 194.898 188.019 206.232 1.00 100.72 ? 6   LEU B CB  1 
ATOM 4888 C CG  . LEU D 3 6   ? 194.844 187.431 204.822 1.00 100.72 ? 6   LEU B CG  1 
ATOM 4889 C CD1 . LEU D 3 6   ? 194.245 186.036 204.853 1.00 100.72 ? 6   LEU B CD1 1 
ATOM 4890 C CD2 . LEU D 3 6   ? 194.040 188.332 203.902 1.00 100.72 ? 6   LEU B CD2 1 
ATOM 4891 N N   . GLN D 3 7   ? 194.755 190.156 208.603 1.00 102.64 ? 7   GLN B N   1 
ATOM 4892 C CA  . GLN D 3 7   ? 194.931 190.440 210.019 1.00 102.64 ? 7   GLN B CA  1 
ATOM 4893 C C   . GLN D 3 7   ? 194.026 189.524 210.827 1.00 102.64 ? 7   GLN B C   1 
ATOM 4894 O O   . GLN D 3 7   ? 192.829 189.420 210.542 1.00 102.64 ? 7   GLN B O   1 
ATOM 4895 C CB  . GLN D 3 7   ? 194.619 191.904 210.333 1.00 102.64 ? 7   GLN B CB  1 
ATOM 4896 C CG  . GLN D 3 7   ? 194.879 192.296 211.778 1.00 102.64 ? 7   GLN B CG  1 
ATOM 4897 C CD  . GLN D 3 7   ? 194.662 193.776 212.028 1.00 102.64 ? 7   GLN B CD  1 
ATOM 4898 O OE1 . GLN D 3 7   ? 194.252 194.515 211.132 1.00 102.64 ? 7   GLN B OE1 1 
ATOM 4899 N NE2 . GLN D 3 7   ? 194.935 194.216 213.250 1.00 102.64 ? 7   GLN B NE2 1 
ATOM 4900 N N   . SER D 3 8   ? 194.597 188.868 211.831 1.00 104.11 ? 8   SER B N   1 
ATOM 4901 C CA  . SER D 3 8   ? 193.844 187.956 212.674 1.00 104.11 ? 8   SER B CA  1 
ATOM 4902 C C   . SER D 3 8   ? 193.053 188.739 213.720 1.00 104.11 ? 8   SER B C   1 
ATOM 4903 O O   . SER D 3 8   ? 193.099 189.970 213.781 1.00 104.11 ? 8   SER B O   1 
ATOM 4904 C CB  . SER D 3 8   ? 194.781 186.943 213.327 1.00 104.11 ? 8   SER B CB  1 
ATOM 4905 O OG  . SER D 3 8   ? 195.262 187.425 214.568 1.00 104.11 ? 8   SER B OG  1 
ATOM 4906 N N   . SER D 3 9   ? 192.312 188.012 214.558 1.00 103.72 ? 9   SER B N   1 
ATOM 4907 C CA  . SER D 3 9   ? 191.443 188.667 215.529 1.00 103.72 ? 9   SER B CA  1 
ATOM 4908 C C   . SER D 3 9   ? 192.228 189.281 216.680 1.00 103.72 ? 9   SER B C   1 
ATOM 4909 O O   . SER D 3 9   ? 191.804 190.298 217.240 1.00 103.72 ? 9   SER B O   1 
ATOM 4910 C CB  . SER D 3 9   ? 190.411 187.677 216.067 1.00 103.72 ? 9   SER B CB  1 
ATOM 4911 O OG  . SER D 3 9   ? 189.838 188.148 217.274 1.00 103.72 ? 9   SER B OG  1 
ATOM 4912 N N   . ASP D 3 10  ? 193.362 188.689 217.051 1.00 112.28 ? 10  ASP B N   1 
ATOM 4913 C CA  . ASP D 3 10  ? 194.136 189.190 218.179 1.00 112.28 ? 10  ASP B CA  1 
ATOM 4914 C C   . ASP D 3 10  ? 195.111 190.296 217.795 1.00 112.28 ? 10  ASP B C   1 
ATOM 4915 O O   . ASP D 3 10  ? 195.766 190.854 218.681 1.00 112.28 ? 10  ASP B O   1 
ATOM 4916 C CB  . ASP D 3 10  ? 194.900 188.045 218.855 1.00 112.28 ? 10  ASP B CB  1 
ATOM 4917 C CG  . ASP D 3 10  ? 195.595 187.139 217.863 1.00 112.28 ? 10  ASP B CG  1 
ATOM 4918 O OD1 . ASP D 3 10  ? 195.644 187.492 216.669 1.00 112.28 ? 10  ASP B OD1 1 
ATOM 4919 O OD2 . ASP D 3 10  ? 196.090 186.071 218.280 1.00 112.28 ? 10  ASP B OD2 1 
ATOM 4920 N N   . GLY D 3 11  ? 195.225 190.626 216.511 1.00 113.41 ? 11  GLY B N   1 
ATOM 4921 C CA  . GLY D 3 11  ? 196.023 191.766 216.105 1.00 113.41 ? 11  GLY B CA  1 
ATOM 4922 C C   . GLY D 3 11  ? 197.278 191.437 215.324 1.00 113.41 ? 11  GLY B C   1 
ATOM 4923 O O   . GLY D 3 11  ? 198.084 192.329 215.041 1.00 113.41 ? 11  GLY B O   1 
ATOM 4924 N N   . GLU D 3 12  ? 197.462 190.171 214.969 1.00 112.96 ? 12  GLU B N   1 
ATOM 4925 C CA  . GLU D 3 12  ? 198.621 189.745 214.199 1.00 112.96 ? 12  GLU B CA  1 
ATOM 4926 C C   . GLU D 3 12  ? 198.341 189.873 212.707 1.00 112.96 ? 12  GLU B C   1 
ATOM 4927 O O   . GLU D 3 12  ? 197.196 189.776 212.260 1.00 112.96 ? 12  GLU B O   1 
ATOM 4928 C CB  . GLU D 3 12  ? 199.004 188.305 214.543 1.00 112.96 ? 12  GLU B CB  1 
ATOM 4929 C CG  . GLU D 3 12  ? 199.378 188.095 216.002 1.00 112.96 ? 12  GLU B CG  1 
ATOM 4930 C CD  . GLU D 3 12  ? 200.849 188.347 216.276 1.00 112.96 ? 12  GLU B CD  1 
ATOM 4931 O OE1 . GLU D 3 12  ? 201.411 189.306 215.707 1.00 112.96 ? 12  GLU B OE1 1 
ATOM 4932 O OE2 . GLU D 3 12  ? 201.445 187.582 217.063 1.00 112.96 ? 12  GLU B OE2 1 
ATOM 4933 N N   . ILE D 3 13  ? 199.405 190.094 211.938 1.00 106.58 ? 13  ILE B N   1 
ATOM 4934 C CA  . ILE D 3 13  ? 199.317 190.332 210.502 1.00 106.58 ? 13  ILE B CA  1 
ATOM 4935 C C   . ILE D 3 13  ? 200.182 189.305 209.788 1.00 106.58 ? 13  ILE B C   1 
ATOM 4936 O O   . ILE D 3 13  ? 201.339 189.089 210.168 1.00 106.58 ? 13  ILE B O   1 
ATOM 4937 C CB  . ILE D 3 13  ? 199.752 191.761 210.125 1.00 106.58 ? 13  ILE B CB  1 
ATOM 4938 C CG1 . ILE D 3 13  ? 198.978 192.807 210.935 1.00 106.58 ? 13  ILE B CG1 1 
ATOM 4939 C CG2 . ILE D 3 13  ? 199.569 191.999 208.635 1.00 106.58 ? 13  ILE B CG2 1 
ATOM 4940 C CD1 . ILE D 3 13  ? 199.652 193.223 212.230 1.00 106.58 ? 13  ILE B CD1 1 
ATOM 4941 N N   . PHE D 3 14  ? 199.622 188.672 208.759 1.00 103.19 ? 14  PHE B N   1 
ATOM 4942 C CA  . PHE D 3 14  ? 200.338 187.687 207.957 1.00 103.19 ? 14  PHE B CA  1 
ATOM 4943 C C   . PHE D 3 14  ? 200.093 187.990 206.487 1.00 103.19 ? 14  PHE B C   1 
ATOM 4944 O O   . PHE D 3 14  ? 198.957 188.265 206.090 1.00 103.19 ? 14  PHE B O   1 
ATOM 4945 C CB  . PHE D 3 14  ? 199.892 186.262 208.296 1.00 103.19 ? 14  PHE B CB  1 
ATOM 4946 C CG  . PHE D 3 14  ? 199.855 185.980 209.768 1.00 103.19 ? 14  PHE B CG  1 
ATOM 4947 C CD1 . PHE D 3 14  ? 198.710 186.229 210.505 1.00 103.19 ? 14  PHE B CD1 1 
ATOM 4948 C CD2 . PHE D 3 14  ? 200.974 185.502 210.423 1.00 103.19 ? 14  PHE B CD2 1 
ATOM 4949 C CE1 . PHE D 3 14  ? 198.674 185.979 211.861 1.00 103.19 ? 14  PHE B CE1 1 
ATOM 4950 C CE2 . PHE D 3 14  ? 200.947 185.259 211.781 1.00 103.19 ? 14  PHE B CE2 1 
ATOM 4951 C CZ  . PHE D 3 14  ? 199.794 185.493 212.500 1.00 103.19 ? 14  PHE B CZ  1 
ATOM 4952 N N   . GLU D 3 15  ? 201.153 187.938 205.687 1.00 109.10 ? 15  GLU B N   1 
ATOM 4953 C CA  . GLU D 3 15  ? 201.081 188.235 204.262 1.00 109.10 ? 15  GLU B CA  1 
ATOM 4954 C C   . GLU D 3 15  ? 200.991 186.923 203.493 1.00 109.10 ? 15  GLU B C   1 
ATOM 4955 O O   . GLU D 3 15  ? 201.832 186.036 203.672 1.00 109.10 ? 15  GLU B O   1 
ATOM 4956 C CB  . GLU D 3 15  ? 202.296 189.054 203.820 1.00 109.10 ? 15  GLU B CB  1 
ATOM 4957 C CG  . GLU D 3 15  ? 202.178 189.697 202.441 1.00 109.10 ? 15  GLU B CG  1 
ATOM 4958 C CD  . GLU D 3 15  ? 202.455 188.736 201.301 1.00 109.10 ? 15  GLU B CD  1 
ATOM 4959 O OE1 . GLU D 3 15  ? 203.043 187.662 201.548 1.00 109.10 ? 15  GLU B OE1 1 
ATOM 4960 O OE2 . GLU D 3 15  ? 202.084 189.055 200.152 1.00 109.10 ? 15  GLU B OE2 1 
ATOM 4961 N N   . VAL D 3 16  ? 199.972 186.802 202.644 1.00 108.44 ? 16  VAL B N   1 
ATOM 4962 C CA  . VAL D 3 16  ? 199.721 185.599 201.867 1.00 108.44 ? 16  VAL B CA  1 
ATOM 4963 C C   . VAL D 3 16  ? 199.559 185.983 200.399 1.00 108.44 ? 16  VAL B C   1 
ATOM 4964 O O   . VAL D 3 16  ? 199.364 187.148 200.055 1.00 108.44 ? 16  VAL B O   1 
ATOM 4965 C CB  . VAL D 3 16  ? 198.484 184.824 202.368 1.00 108.44 ? 16  VAL B CB  1 
ATOM 4966 C CG1 . VAL D 3 16  ? 198.473 184.749 203.887 1.00 108.44 ? 16  VAL B CG1 1 
ATOM 4967 C CG2 . VAL D 3 16  ? 197.209 185.470 201.853 1.00 108.44 ? 16  VAL B CG2 1 
ATOM 4968 N N   . ASP D 3 17  ? 199.653 184.978 199.534 1.00 112.76 ? 17  ASP B N   1 
ATOM 4969 C CA  . ASP D 3 17  ? 199.483 185.185 198.105 1.00 112.76 ? 17  ASP B CA  1 
ATOM 4970 C C   . ASP D 3 17  ? 198.002 185.336 197.762 1.00 112.76 ? 17  ASP B C   1 
ATOM 4971 O O   . ASP D 3 17  ? 197.125 184.812 198.453 1.00 112.76 ? 17  ASP B O   1 
ATOM 4972 C CB  . ASP D 3 17  ? 200.118 184.020 197.338 1.00 112.76 ? 17  ASP B CB  1 
ATOM 4973 C CG  . ASP D 3 17  ? 199.608 183.893 195.919 1.00 112.76 ? 17  ASP B CG  1 
ATOM 4974 O OD1 . ASP D 3 17  ? 198.520 183.316 195.728 1.00 112.76 ? 17  ASP B OD1 1 
ATOM 4975 O OD2 . ASP D 3 17  ? 200.298 184.369 194.993 1.00 112.76 ? 17  ASP B OD2 1 
ATOM 4976 N N   . VAL D 3 18  ? 197.725 186.083 196.691 1.00 111.27 ? 18  VAL B N   1 
ATOM 4977 C CA  . VAL D 3 18  ? 196.338 186.334 196.306 1.00 111.27 ? 18  VAL B CA  1 
ATOM 4978 C C   . VAL D 3 18  ? 195.660 185.052 195.839 1.00 111.27 ? 18  VAL B C   1 
ATOM 4979 O O   . VAL D 3 18  ? 194.550 184.730 196.276 1.00 111.27 ? 18  VAL B O   1 
ATOM 4980 C CB  . VAL D 3 18  ? 196.269 187.433 195.232 1.00 111.27 ? 18  VAL B CB  1 
ATOM 4981 C CG1 . VAL D 3 18  ? 194.823 187.721 194.867 1.00 111.27 ? 18  VAL B CG1 1 
ATOM 4982 C CG2 . VAL D 3 18  ? 196.945 188.694 195.733 1.00 111.27 ? 18  VAL B CG2 1 
ATOM 4983 N N   . GLU D 3 19  ? 196.310 184.300 194.945 1.00 111.50 ? 19  GLU B N   1 
ATOM 4984 C CA  . GLU D 3 19  ? 195.704 183.070 194.445 1.00 111.50 ? 19  GLU B CA  1 
ATOM 4985 C C   . GLU D 3 19  ? 195.517 182.045 195.554 1.00 111.50 ? 19  GLU B C   1 
ATOM 4986 O O   . GLU D 3 19  ? 194.507 181.333 195.573 1.00 111.50 ? 19  GLU B O   1 
ATOM 4987 C CB  . GLU D 3 19  ? 196.553 182.479 193.320 1.00 111.50 ? 19  GLU B CB  1 
ATOM 4988 C CG  . GLU D 3 19  ? 196.776 183.420 192.151 1.00 111.50 ? 19  GLU B CG  1 
ATOM 4989 C CD  . GLU D 3 19  ? 195.510 183.661 191.354 1.00 111.50 ? 19  GLU B CD  1 
ATOM 4990 O OE1 . GLU D 3 19  ? 194.635 182.770 191.344 1.00 111.50 ? 19  GLU B OE1 1 
ATOM 4991 O OE2 . GLU D 3 19  ? 195.391 184.739 190.736 1.00 111.50 ? 19  GLU B OE2 1 
ATOM 4992 N N   . ILE D 3 20  ? 196.474 181.951 196.480 1.00 109.49 ? 20  ILE B N   1 
ATOM 4993 C CA  . ILE D 3 20  ? 196.322 181.034 197.604 1.00 109.49 ? 20  ILE B CA  1 
ATOM 4994 C C   . ILE D 3 20  ? 195.198 181.498 198.521 1.00 109.49 ? 20  ILE B C   1 
ATOM 4995 O O   . ILE D 3 20  ? 194.553 180.681 199.190 1.00 109.49 ? 20  ILE B O   1 
ATOM 4996 C CB  . ILE D 3 20  ? 197.661 180.882 198.354 1.00 109.49 ? 20  ILE B CB  1 
ATOM 4997 C CG1 . ILE D 3 20  ? 197.759 179.506 199.004 1.00 109.49 ? 20  ILE B CG1 1 
ATOM 4998 C CG2 . ILE D 3 20  ? 197.829 181.950 199.421 1.00 109.49 ? 20  ILE B CG2 1 
ATOM 4999 C CD1 . ILE D 3 20  ? 199.166 179.143 199.374 1.00 109.49 ? 20  ILE B CD1 1 
ATOM 5000 N N   . ALA D 3 21  ? 194.944 182.808 198.571 1.00 99.53  ? 21  ALA B N   1 
ATOM 5001 C CA  . ALA D 3 21  ? 193.806 183.324 199.321 1.00 99.53  ? 21  ALA B CA  1 
ATOM 5002 C C   . ALA D 3 21  ? 192.506 183.125 198.553 1.00 99.53  ? 21  ALA B C   1 
ATOM 5003 O O   . ALA D 3 21  ? 191.434 183.001 199.154 1.00 99.53  ? 21  ALA B O   1 
ATOM 5004 C CB  . ALA D 3 21  ? 194.018 184.803 199.649 1.00 99.53  ? 21  ALA B CB  1 
ATOM 5005 N N   . LYS D 3 22  ? 192.584 183.083 197.223 1.00 96.24  ? 22  LYS B N   1 
ATOM 5006 C CA  . LYS D 3 22  ? 191.399 182.908 196.392 1.00 96.24  ? 22  LYS B CA  1 
ATOM 5007 C C   . LYS D 3 22  ? 190.848 181.495 196.522 1.00 96.24  ? 22  LYS B C   1 
ATOM 5008 O O   . LYS D 3 22  ? 189.763 181.198 196.014 1.00 96.24  ? 22  LYS B O   1 
ATOM 5009 C CB  . LYS D 3 22  ? 191.706 183.224 194.927 1.00 96.24  ? 22  LYS B CB  1 
ATOM 5010 C CG  . LYS D 3 22  ? 191.785 184.708 194.619 1.00 96.24  ? 22  LYS B CG  1 
ATOM 5011 C CD  . LYS D 3 22  ? 192.104 184.952 193.154 1.00 96.24  ? 22  LYS B CD  1 
ATOM 5012 C CE  . LYS D 3 22  ? 191.031 185.801 192.492 1.00 96.24  ? 22  LYS B CE  1 
ATOM 5013 N NZ  . LYS D 3 22  ? 190.814 185.412 191.072 1.00 96.24  ? 22  LYS B NZ  1 
ATOM 5014 N N   . GLN D 3 23  ? 191.594 180.614 197.185 1.00 94.72  ? 23  GLN B N   1 
ATOM 5015 C CA  . GLN D 3 23  ? 191.089 179.285 197.500 1.00 94.72  ? 23  GLN B CA  1 
ATOM 5016 C C   . GLN D 3 23  ? 189.844 179.370 198.376 1.00 94.72  ? 23  GLN B C   1 
ATOM 5017 O O   . GLN D 3 23  ? 188.884 178.622 198.172 1.00 94.72  ? 23  GLN B O   1 
ATOM 5018 C CB  . GLN D 3 23  ? 192.177 178.455 198.187 1.00 94.72  ? 23  GLN B CB  1 
ATOM 5019 C CG  . GLN D 3 23  ? 191.766 177.026 198.491 1.00 94.72  ? 23  GLN B CG  1 
ATOM 5020 C CD  . GLN D 3 23  ? 191.484 176.221 197.240 1.00 94.72  ? 23  GLN B CD  1 
ATOM 5021 O OE1 . GLN D 3 23  ? 192.189 176.342 196.239 1.00 94.72  ? 23  GLN B OE1 1 
ATOM 5022 N NE2 . GLN D 3 23  ? 190.445 175.394 197.289 1.00 94.72  ? 23  GLN B NE2 1 
ATOM 5023 N N   . SER D 3 24  ? 189.851 180.275 199.350 1.00 83.94  ? 24  SER B N   1 
ATOM 5024 C CA  . SER D 3 24  ? 188.651 180.555 200.125 1.00 83.94  ? 24  SER B CA  1 
ATOM 5025 C C   . SER D 3 24  ? 187.678 181.379 199.294 1.00 83.94  ? 24  SER B C   1 
ATOM 5026 O O   . SER D 3 24  ? 188.056 182.402 198.716 1.00 83.94  ? 24  SER B O   1 
ATOM 5027 C CB  . SER D 3 24  ? 189.022 181.295 201.408 1.00 83.94  ? 24  SER B CB  1 
ATOM 5028 O OG  . SER D 3 24  ? 187.868 181.804 202.051 1.00 83.94  ? 24  SER B OG  1 
ATOM 5029 N N   . VAL D 3 25  ? 186.422 180.933 199.237 1.00 76.20  ? 25  VAL B N   1 
ATOM 5030 C CA  . VAL D 3 25  ? 185.426 181.625 198.423 1.00 76.20  ? 25  VAL B CA  1 
ATOM 5031 C C   . VAL D 3 25  ? 185.130 183.006 198.992 1.00 76.20  ? 25  VAL B C   1 
ATOM 5032 O O   . VAL D 3 25  ? 184.990 183.984 198.247 1.00 76.20  ? 25  VAL B O   1 
ATOM 5033 C CB  . VAL D 3 25  ? 184.151 180.771 198.300 1.00 76.20  ? 25  VAL B CB  1 
ATOM 5034 C CG1 . VAL D 3 25  ? 183.088 181.516 197.517 1.00 76.20  ? 25  VAL B CG1 1 
ATOM 5035 C CG2 . VAL D 3 25  ? 184.472 179.456 197.615 1.00 76.20  ? 25  VAL B CG2 1 
ATOM 5036 N N   . THR D 3 26  ? 185.035 183.111 200.319 1.00 70.14  ? 26  THR B N   1 
ATOM 5037 C CA  . THR D 3 26  ? 184.693 184.387 200.941 1.00 70.14  ? 26  THR B CA  1 
ATOM 5038 C C   . THR D 3 26  ? 185.718 185.464 200.610 1.00 70.14  ? 26  THR B C   1 
ATOM 5039 O O   . THR D 3 26  ? 185.350 186.598 200.280 1.00 70.14  ? 26  THR B O   1 
ATOM 5040 C CB  . THR D 3 26  ? 184.575 184.215 202.453 1.00 70.14  ? 26  THR B CB  1 
ATOM 5041 O OG1 . THR D 3 26  ? 183.400 183.456 202.760 1.00 70.14  ? 26  THR B OG1 1 
ATOM 5042 C CG2 . THR D 3 26  ? 184.505 185.566 203.138 1.00 70.14  ? 26  THR B CG2 1 
ATOM 5043 N N   . ILE D 3 27  ? 187.006 185.133 200.691 1.00 74.23  ? 27  ILE B N   1 
ATOM 5044 C CA  . ILE D 3 27  ? 188.041 186.119 200.399 1.00 74.23  ? 27  ILE B CA  1 
ATOM 5045 C C   . ILE D 3 27  ? 187.976 186.550 198.940 1.00 74.23  ? 27  ILE B C   1 
ATOM 5046 O O   . ILE D 3 27  ? 188.066 187.744 198.628 1.00 74.23  ? 27  ILE B O   1 
ATOM 5047 C CB  . ILE D 3 27  ? 189.427 185.563 200.771 1.00 74.23  ? 27  ILE B CB  1 
ATOM 5048 C CG1 . ILE D 3 27  ? 189.654 185.688 202.277 1.00 74.23  ? 27  ILE B CG1 1 
ATOM 5049 C CG2 . ILE D 3 27  ? 190.522 186.296 200.015 1.00 74.23  ? 27  ILE B CG2 1 
ATOM 5050 C CD1 . ILE D 3 27  ? 189.647 187.115 202.768 1.00 74.23  ? 27  ILE B CD1 1 
ATOM 5051 N N   . LYS D 3 28  ? 187.807 185.595 198.023 1.00 77.73  ? 28  LYS B N   1 
ATOM 5052 C CA  . LYS D 3 28  ? 187.859 185.928 196.602 1.00 77.73  ? 28  LYS B CA  1 
ATOM 5053 C C   . LYS D 3 28  ? 186.621 186.704 196.165 1.00 77.73  ? 28  LYS B C   1 
ATOM 5054 O O   . LYS D 3 28  ? 186.701 187.565 195.282 1.00 77.73  ? 28  LYS B O   1 
ATOM 5055 C CB  . LYS D 3 28  ? 188.034 184.659 195.763 1.00 77.73  ? 28  LYS B CB  1 
ATOM 5056 C CG  . LYS D 3 28  ? 186.798 183.790 195.639 1.00 77.73  ? 28  LYS B CG  1 
ATOM 5057 C CD  . LYS D 3 28  ? 186.946 182.804 194.496 1.00 77.73  ? 28  LYS B CD  1 
ATOM 5058 C CE  . LYS D 3 28  ? 185.624 182.134 194.175 1.00 77.73  ? 28  LYS B CE  1 
ATOM 5059 N NZ  . LYS D 3 28  ? 185.729 181.242 192.989 1.00 77.73  ? 28  LYS B NZ  1 
ATOM 5060 N N   . THR D 3 29  ? 185.464 186.416 196.769 1.00 75.31  ? 29  THR B N   1 
ATOM 5061 C CA  . THR D 3 29  ? 184.242 187.123 196.393 1.00 75.31  ? 29  THR B CA  1 
ATOM 5062 C C   . THR D 3 29  ? 184.341 188.604 196.736 1.00 75.31  ? 29  THR B C   1 
ATOM 5063 O O   . THR D 3 29  ? 183.927 189.466 195.953 1.00 75.31  ? 29  THR B O   1 
ATOM 5064 C CB  . THR D 3 29  ? 183.033 186.487 197.080 1.00 75.31  ? 29  THR B CB  1 
ATOM 5065 O OG1 . THR D 3 29  ? 182.847 185.157 196.582 1.00 75.31  ? 29  THR B OG1 1 
ATOM 5066 C CG2 . THR D 3 29  ? 181.777 187.296 196.808 1.00 75.31  ? 29  THR B CG2 1 
ATOM 5067 N N   . MET D 3 30  ? 184.901 188.918 197.902 1.00 81.65  ? 30  MET B N   1 
ATOM 5068 C CA  . MET D 3 30  ? 185.085 190.303 198.312 1.00 81.65  ? 30  MET B CA  1 
ATOM 5069 C C   . MET D 3 30  ? 186.181 190.958 197.480 1.00 81.65  ? 30  MET B C   1 
ATOM 5070 O O   . MET D 3 30  ? 186.141 192.165 197.226 1.00 81.65  ? 30  MET B O   1 
ATOM 5071 C CB  . MET D 3 30  ? 185.414 190.371 199.806 1.00 81.65  ? 30  MET B CB  1 
ATOM 5072 C CG  . MET D 3 30  ? 186.053 191.670 200.272 1.00 81.65  ? 30  MET B CG  1 
ATOM 5073 S SD  . MET D 3 30  ? 187.853 191.603 200.331 1.00 81.65  ? 30  MET B SD  1 
ATOM 5074 C CE  . MET D 3 30  ? 188.111 191.100 202.028 1.00 81.65  ? 30  MET B CE  1 
ATOM 5075 N N   . LEU D 3 31  ? 187.151 190.165 197.030 1.00 90.93  ? 31  LEU B N   1 
ATOM 5076 C CA  . LEU D 3 31  ? 188.291 190.684 196.288 1.00 90.93  ? 31  LEU B CA  1 
ATOM 5077 C C   . LEU D 3 31  ? 188.074 190.751 194.786 1.00 90.93  ? 31  LEU B C   1 
ATOM 5078 O O   . LEU D 3 31  ? 188.964 191.215 194.072 1.00 90.93  ? 31  LEU B O   1 
ATOM 5079 C CB  . LEU D 3 31  ? 189.537 189.833 196.561 1.00 90.93  ? 31  LEU B CB  1 
ATOM 5080 C CG  . LEU D 3 31  ? 190.671 190.503 197.338 1.00 90.93  ? 31  LEU B CG  1 
ATOM 5081 C CD1 . LEU D 3 31  ? 191.908 189.622 197.333 1.00 90.93  ? 31  LEU B CD1 1 
ATOM 5082 C CD2 . LEU D 3 31  ? 190.982 191.876 196.764 1.00 90.93  ? 31  LEU B CD2 1 
ATOM 5083 N N   . GLU D 3 32  ? 186.921 190.306 194.287 1.00 96.94  ? 32  GLU B N   1 
ATOM 5084 C CA  . GLU D 3 32  ? 186.657 190.265 192.855 1.00 96.94  ? 32  GLU B CA  1 
ATOM 5085 C C   . GLU D 3 32  ? 185.456 191.124 192.467 1.00 96.94  ? 32  GLU B C   1 
ATOM 5086 O O   . GLU D 3 32  ? 185.402 191.662 191.358 1.00 96.94  ? 32  GLU B O   1 
ATOM 5087 C CB  . GLU D 3 32  ? 186.467 188.818 192.398 1.00 96.94  ? 32  GLU B CB  1 
ATOM 5088 C CG  . GLU D 3 32  ? 185.437 188.607 191.303 1.00 96.94  ? 32  GLU B CG  1 
ATOM 5089 C CD  . GLU D 3 32  ? 185.029 187.154 191.166 1.00 96.94  ? 32  GLU B CD  1 
ATOM 5090 O OE1 . GLU D 3 32  ? 185.858 186.345 190.701 1.00 96.94  ? 32  GLU B OE1 1 
ATOM 5091 O OE2 . GLU D 3 32  ? 183.878 186.822 191.518 1.00 96.94  ? 32  GLU B OE2 1 
ATOM 5092 N N   . ASP D 3 33  ? 184.504 191.292 193.379 1.00 90.86  ? 33  ASP B N   1 
ATOM 5093 C CA  . ASP D 3 33  ? 183.305 192.070 193.089 1.00 90.86  ? 33  ASP B CA  1 
ATOM 5094 C C   . ASP D 3 33  ? 183.395 193.435 193.768 1.00 90.86  ? 33  ASP B C   1 
ATOM 5095 O O   . ASP D 3 33  ? 182.531 194.296 193.603 1.00 90.86  ? 33  ASP B O   1 
ATOM 5096 C CB  . ASP D 3 33  ? 182.048 191.315 193.521 1.00 90.86  ? 33  ASP B CB  1 
ATOM 5097 C CG  . ASP D 3 33  ? 181.866 190.012 192.773 1.00 90.86  ? 33  ASP B CG  1 
ATOM 5098 O OD1 . ASP D 3 33  ? 182.442 189.870 191.674 1.00 90.86  ? 33  ASP B OD1 1 
ATOM 5099 O OD2 . ASP D 3 33  ? 181.143 189.129 193.281 1.00 90.86  ? 33  ASP B OD2 1 
ATOM 5100 N N   . LEU D 3 34  ? 184.450 193.643 194.552 1.00 96.48  ? 34  LEU B N   1 
ATOM 5101 C CA  . LEU D 3 34  ? 184.639 194.917 195.235 1.00 96.48  ? 34  LEU B CA  1 
ATOM 5102 C C   . LEU D 3 34  ? 186.041 195.467 195.004 1.00 96.48  ? 34  LEU B C   1 
ATOM 5103 O O   . LEU D 3 34  ? 186.238 196.685 194.970 1.00 96.48  ? 34  LEU B O   1 
ATOM 5104 C CB  . LEU D 3 34  ? 184.360 194.762 196.730 1.00 96.48  ? 34  LEU B CB  1 
ATOM 5105 C CG  . LEU D 3 34  ? 184.352 196.028 197.584 1.00 96.48  ? 34  LEU B CG  1 
ATOM 5106 C CD1 . LEU D 3 34  ? 183.244 195.960 198.616 1.00 96.48  ? 34  LEU B CD1 1 
ATOM 5107 C CD2 . LEU D 3 34  ? 185.696 196.207 198.266 1.00 96.48  ? 34  LEU B CD2 1 
ATOM 5108 N N   . GLY D 3 35  ? 187.018 194.578 194.841 1.00 122.27 ? 35  GLY B N   1 
ATOM 5109 C CA  . GLY D 3 35  ? 188.411 194.977 194.787 1.00 122.27 ? 35  GLY B CA  1 
ATOM 5110 C C   . GLY D 3 35  ? 188.864 195.544 193.457 1.00 122.27 ? 35  GLY B C   1 
ATOM 5111 O O   . GLY D 3 35  ? 190.056 195.798 193.261 1.00 122.27 ? 35  GLY B O   1 
ATOM 5112 N N   . MET D 3 36  ? 187.928 195.745 192.535 1.00 142.39 ? 36  MET B N   1 
ATOM 5113 C CA  . MET D 3 36  ? 188.242 196.308 191.221 1.00 142.39 ? 36  MET B CA  1 
ATOM 5114 C C   . MET D 3 36  ? 188.350 197.830 191.276 1.00 142.39 ? 36  MET B C   1 
ATOM 5115 O O   . MET D 3 36  ? 187.648 198.552 190.569 1.00 142.39 ? 36  MET B O   1 
ATOM 5116 C CB  . MET D 3 36  ? 187.195 195.869 190.206 1.00 142.39 ? 36  MET B CB  1 
ATOM 5117 C CG  . MET D 3 36  ? 187.097 194.361 190.025 1.00 142.39 ? 36  MET B CG  1 
ATOM 5118 S SD  . MET D 3 36  ? 188.654 193.609 189.512 1.00 142.39 ? 36  MET B SD  1 
ATOM 5119 C CE  . MET D 3 36  ? 189.122 192.738 191.006 1.00 142.39 ? 36  MET B CE  1 
ATOM 5120 N N   . ASP D 3 37  ? 189.244 198.328 192.127 1.00 146.56 ? 37  ASP B N   1 
ATOM 5121 C CA  . ASP D 3 37  ? 189.463 199.756 192.312 1.00 146.56 ? 37  ASP B CA  1 
ATOM 5122 C C   . ASP D 3 37  ? 190.864 199.987 192.869 1.00 146.56 ? 37  ASP B C   1 
ATOM 5123 O O   . ASP D 3 37  ? 191.620 199.044 193.122 1.00 146.56 ? 37  ASP B O   1 
ATOM 5124 C CB  . ASP D 3 37  ? 188.381 200.364 193.218 1.00 146.56 ? 37  ASP B CB  1 
ATOM 5125 C CG  . ASP D 3 37  ? 188.704 200.242 194.704 1.00 146.56 ? 37  ASP B CG  1 
ATOM 5126 O OD1 . ASP D 3 37  ? 189.352 199.255 195.114 1.00 146.56 ? 37  ASP B OD1 1 
ATOM 5127 O OD2 . ASP D 3 37  ? 188.257 201.117 195.475 1.00 146.56 ? 37  ASP B OD2 1 
ATOM 5128 N N   . ASP D 3 38  ? 191.211 201.258 193.059 1.00 149.79 ? 38  ASP B N   1 
ATOM 5129 C CA  . ASP D 3 38  ? 192.480 201.610 193.687 1.00 149.79 ? 38  ASP B CA  1 
ATOM 5130 C C   . ASP D 3 38  ? 192.428 201.211 195.156 1.00 149.79 ? 38  ASP B C   1 
ATOM 5131 O O   . ASP D 3 38  ? 191.772 201.872 195.967 1.00 149.79 ? 38  ASP B O   1 
ATOM 5132 C CB  . ASP D 3 38  ? 192.759 203.101 193.530 1.00 149.79 ? 38  ASP B CB  1 
ATOM 5133 C CG  . ASP D 3 38  ? 194.122 203.498 194.066 1.00 149.79 ? 38  ASP B CG  1 
ATOM 5134 O OD1 . ASP D 3 38  ? 194.252 203.678 195.295 1.00 149.79 ? 38  ASP B OD1 1 
ATOM 5135 O OD2 . ASP D 3 38  ? 195.065 203.627 193.257 1.00 149.79 ? 38  ASP B OD2 1 
ATOM 5136 N N   . GLU D 3 39  ? 193.116 200.123 195.496 1.00 150.75 ? 39  GLU B N   1 
ATOM 5137 C CA  . GLU D 3 39  ? 193.056 199.565 196.839 1.00 150.75 ? 39  GLU B CA  1 
ATOM 5138 C C   . GLU D 3 39  ? 193.689 200.505 197.856 1.00 150.75 ? 39  GLU B C   1 
ATOM 5139 O O   . GLU D 3 39  ? 194.573 201.300 197.526 1.00 150.75 ? 39  GLU B O   1 
ATOM 5140 C CB  . GLU D 3 39  ? 193.756 198.201 196.863 1.00 150.75 ? 39  GLU B CB  1 
ATOM 5141 C CG  . GLU D 3 39  ? 195.244 198.246 197.195 1.00 150.75 ? 39  GLU B CG  1 
ATOM 5142 C CD  . GLU D 3 39  ? 196.062 198.989 196.153 1.00 150.75 ? 39  GLU B CD  1 
ATOM 5143 O OE1 . GLU D 3 39  ? 195.661 198.994 194.970 1.00 150.75 ? 39  GLU B OE1 1 
ATOM 5144 O OE2 . GLU D 3 39  ? 197.106 199.569 196.519 1.00 150.75 ? 39  GLU B OE2 1 
ATOM 5145 N N   . GLY D 3 40  ? 193.203 200.428 199.094 1.00 146.05 ? 40  GLY B N   1 
ATOM 5146 C CA  . GLY D 3 40  ? 193.879 201.068 200.204 1.00 146.05 ? 40  GLY B CA  1 
ATOM 5147 C C   . GLY D 3 40  ? 195.281 200.511 200.309 1.00 146.05 ? 40  GLY B C   1 
ATOM 5148 O O   . GLY D 3 40  ? 195.472 199.303 200.141 1.00 146.05 ? 40  GLY B O   1 
ATOM 5149 N N   . ASP D 3 41  ? 196.268 201.363 200.592 1.00 149.62 ? 41  ASP B N   1 
ATOM 5150 C CA  . ASP D 3 41  ? 197.657 200.978 200.376 1.00 149.62 ? 41  ASP B CA  1 
ATOM 5151 C C   . ASP D 3 41  ? 198.044 199.797 201.255 1.00 149.62 ? 41  ASP B C   1 
ATOM 5152 O O   . ASP D 3 41  ? 198.292 199.955 202.455 1.00 149.62 ? 41  ASP B O   1 
ATOM 5153 C CB  . ASP D 3 41  ? 198.584 202.166 200.642 1.00 149.62 ? 41  ASP B CB  1 
ATOM 5154 C CG  . ASP D 3 41  ? 198.390 203.291 199.645 1.00 149.62 ? 41  ASP B CG  1 
ATOM 5155 O OD1 . ASP D 3 41  ? 197.437 203.216 198.841 1.00 149.62 ? 41  ASP B OD1 1 
ATOM 5156 O OD2 . ASP D 3 41  ? 199.188 204.252 199.667 1.00 149.62 ? 41  ASP B OD2 1 
ATOM 5157 N N   . ASP D 3 42  ? 198.117 198.615 200.638 1.00 135.77 ? 42  ASP B N   1 
ATOM 5158 C CA  . ASP D 3 42  ? 198.400 197.348 201.305 1.00 135.77 ? 42  ASP B CA  1 
ATOM 5159 C C   . ASP D 3 42  ? 197.612 197.208 202.602 1.00 135.77 ? 42  ASP B C   1 
ATOM 5160 O O   . ASP D 3 42  ? 198.145 196.737 203.612 1.00 135.77 ? 42  ASP B O   1 
ATOM 5161 C CB  . ASP D 3 42  ? 199.899 197.208 201.572 1.00 135.77 ? 42  ASP B CB  1 
ATOM 5162 C CG  . ASP D 3 42  ? 200.396 195.795 201.344 1.00 135.77 ? 42  ASP B CG  1 
ATOM 5163 O OD1 . ASP D 3 42  ? 199.638 194.845 201.633 1.00 135.77 ? 42  ASP B OD1 1 
ATOM 5164 O OD2 . ASP D 3 42  ? 201.542 195.632 200.874 1.00 135.77 ? 42  ASP B OD2 1 
ATOM 5165 N N   . ASP D 3 43  ? 196.347 197.621 202.584 1.00 132.18 ? 43  ASP B N   1 
ATOM 5166 C CA  . ASP D 3 43  ? 195.544 197.613 203.794 1.00 132.18 ? 43  ASP B CA  1 
ATOM 5167 C C   . ASP D 3 43  ? 195.237 196.179 204.225 1.00 132.18 ? 43  ASP B C   1 
ATOM 5168 O O   . ASP D 3 43  ? 194.797 195.357 203.415 1.00 132.18 ? 43  ASP B O   1 
ATOM 5169 C CB  . ASP D 3 43  ? 194.244 198.384 203.576 1.00 132.18 ? 43  ASP B CB  1 
ATOM 5170 C CG  . ASP D 3 43  ? 194.426 199.882 203.717 1.00 132.18 ? 43  ASP B CG  1 
ATOM 5171 O OD1 . ASP D 3 43  ? 195.543 200.315 204.070 1.00 132.18 ? 43  ASP B OD1 1 
ATOM 5172 O OD2 . ASP D 3 43  ? 193.453 200.626 203.476 1.00 132.18 ? 43  ASP B OD2 1 
ATOM 5173 N N   . PRO D 3 44  ? 195.462 195.853 205.494 1.00 113.77 ? 44  PRO B N   1 
ATOM 5174 C CA  . PRO D 3 44  ? 195.156 194.502 205.973 1.00 113.77 ? 44  PRO B CA  1 
ATOM 5175 C C   . PRO D 3 44  ? 193.658 194.251 206.020 1.00 113.77 ? 44  PRO B C   1 
ATOM 5176 O O   . PRO D 3 44  ? 192.851 195.174 206.148 1.00 113.77 ? 44  PRO B O   1 
ATOM 5177 C CB  . PRO D 3 44  ? 195.766 194.479 207.378 1.00 113.77 ? 44  PRO B CB  1 
ATOM 5178 C CG  . PRO D 3 44  ? 195.756 195.907 207.806 1.00 113.77 ? 44  PRO B CG  1 
ATOM 5179 C CD  . PRO D 3 44  ? 196.005 196.711 206.561 1.00 113.77 ? 44  PRO B CD  1 
ATOM 5180 N N   . VAL D 3 45  ? 193.292 192.977 205.918 1.00 103.19 ? 45  VAL B N   1 
ATOM 5181 C CA  . VAL D 3 45  ? 191.893 192.567 206.005 1.00 103.19 ? 45  VAL B CA  1 
ATOM 5182 C C   . VAL D 3 45  ? 191.694 191.891 207.357 1.00 103.19 ? 45  VAL B C   1 
ATOM 5183 O O   . VAL D 3 45  ? 192.129 190.747 207.552 1.00 103.19 ? 45  VAL B O   1 
ATOM 5184 C CB  . VAL D 3 45  ? 191.505 191.643 204.840 1.00 103.19 ? 45  VAL B CB  1 
ATOM 5185 C CG1 . VAL D 3 45  ? 190.166 190.977 205.108 1.00 103.19 ? 45  VAL B CG1 1 
ATOM 5186 C CG2 . VAL D 3 45  ? 191.469 192.423 203.536 1.00 103.19 ? 45  VAL B CG2 1 
ATOM 5187 N N   . PRO D 3 46  ? 191.067 192.563 208.316 1.00 93.34  ? 46  PRO B N   1 
ATOM 5188 C CA  . PRO D 3 46  ? 190.960 192.053 209.703 1.00 93.34  ? 46  PRO B CA  1 
ATOM 5189 C C   . PRO D 3 46  ? 189.821 191.057 209.906 1.00 93.34  ? 46  PRO B C   1 
ATOM 5190 O O   . PRO D 3 46  ? 188.702 191.416 210.278 1.00 93.34  ? 46  PRO B O   1 
ATOM 5191 C CB  . PRO D 3 46  ? 190.755 193.342 210.502 1.00 93.34  ? 46  PRO B CB  1 
ATOM 5192 C CG  . PRO D 3 46  ? 189.993 194.218 209.565 1.00 93.34  ? 46  PRO B CG  1 
ATOM 5193 C CD  . PRO D 3 46  ? 190.558 193.940 208.197 1.00 93.34  ? 46  PRO B CD  1 
ATOM 5194 N N   . LEU D 3 47  ? 190.099 189.783 209.649 1.00 87.55  ? 47  LEU B N   1 
ATOM 5195 C CA  . LEU D 3 47  ? 189.115 188.740 209.907 1.00 87.55  ? 47  LEU B CA  1 
ATOM 5196 C C   . LEU D 3 47  ? 188.866 188.624 211.410 1.00 87.55  ? 47  LEU B C   1 
ATOM 5197 O O   . LEU D 3 47  ? 189.701 188.066 212.133 1.00 87.55  ? 47  LEU B O   1 
ATOM 5198 C CB  . LEU D 3 47  ? 189.609 187.394 209.369 1.00 87.55  ? 47  LEU B CB  1 
ATOM 5199 C CG  . LEU D 3 47  ? 189.641 187.053 207.878 1.00 87.55  ? 47  LEU B CG  1 
ATOM 5200 C CD1 . LEU D 3 47  ? 190.515 187.999 207.083 1.00 87.55  ? 47  LEU B CD1 1 
ATOM 5201 C CD2 . LEU D 3 47  ? 190.135 185.629 207.715 1.00 87.55  ? 47  LEU B CD2 1 
ATOM 5202 N N   . PRO D 3 48  ? 187.737 189.123 211.920 1.00 83.12  ? 48  PRO B N   1 
ATOM 5203 C CA  . PRO D 3 48  ? 187.549 189.149 213.373 1.00 83.12  ? 48  PRO B CA  1 
ATOM 5204 C C   . PRO D 3 48  ? 186.858 187.915 213.930 1.00 83.12  ? 48  PRO B C   1 
ATOM 5205 O O   . PRO D 3 48  ? 185.950 188.046 214.757 1.00 83.12  ? 48  PRO B O   1 
ATOM 5206 C CB  . PRO D 3 48  ? 186.684 190.396 213.565 1.00 83.12  ? 48  PRO B CB  1 
ATOM 5207 C CG  . PRO D 3 48  ? 185.809 190.404 212.321 1.00 83.12  ? 48  PRO B CG  1 
ATOM 5208 C CD  . PRO D 3 48  ? 186.532 189.613 211.230 1.00 83.12  ? 48  PRO B CD  1 
ATOM 5209 N N   . ASN D 3 49  ? 187.258 186.719 213.503 1.00 83.99  ? 49  ASN B N   1 
ATOM 5210 C CA  . ASN D 3 49  ? 186.685 185.515 214.093 1.00 83.99  ? 49  ASN B CA  1 
ATOM 5211 C C   . ASN D 3 49  ? 187.720 184.406 214.221 1.00 83.99  ? 49  ASN B C   1 
ATOM 5212 O O   . ASN D 3 49  ? 187.401 183.302 214.671 1.00 83.99  ? 49  ASN B O   1 
ATOM 5213 C CB  . ASN D 3 49  ? 185.492 185.033 213.267 1.00 83.99  ? 49  ASN B CB  1 
ATOM 5214 C CG  . ASN D 3 49  ? 184.409 184.401 214.120 1.00 83.99  ? 49  ASN B CG  1 
ATOM 5215 O OD1 . ASN D 3 49  ? 183.221 184.654 213.926 1.00 83.99  ? 49  ASN B OD1 1 
ATOM 5216 N ND2 . ASN D 3 49  ? 184.816 183.572 215.073 1.00 83.99  ? 49  ASN B ND2 1 
ATOM 5217 N N   . VAL D 3 50  ? 188.959 184.685 213.832 1.00 91.48  ? 50  VAL B N   1 
ATOM 5218 C CA  . VAL D 3 50  ? 190.032 183.698 213.852 1.00 91.48  ? 50  VAL B CA  1 
ATOM 5219 C C   . VAL D 3 50  ? 191.262 184.343 214.474 1.00 91.48  ? 50  VAL B C   1 
ATOM 5220 O O   . VAL D 3 50  ? 191.662 185.446 214.082 1.00 91.48  ? 50  VAL B O   1 
ATOM 5221 C CB  . VAL D 3 50  ? 190.331 183.160 212.444 1.00 91.48  ? 50  VAL B CB  1 
ATOM 5222 C CG1 . VAL D 3 50  ? 189.288 182.131 212.044 1.00 91.48  ? 50  VAL B CG1 1 
ATOM 5223 C CG2 . VAL D 3 50  ? 190.362 184.295 211.435 1.00 91.48  ? 50  VAL B CG2 1 
ATOM 5224 N N   . ASN D 3 51  ? 191.860 183.656 215.445 1.00 97.11  ? 51  ASN B N   1 
ATOM 5225 C CA  . ASN D 3 51  ? 193.053 184.167 216.106 1.00 97.11  ? 51  ASN B CA  1 
ATOM 5226 C C   . ASN D 3 51  ? 194.296 183.895 215.268 1.00 97.11  ? 51  ASN B C   1 
ATOM 5227 O O   . ASN D 3 51  ? 194.202 183.333 214.172 1.00 97.11  ? 51  ASN B O   1 
ATOM 5228 C CB  . ASN D 3 51  ? 193.183 183.564 217.509 1.00 97.11  ? 51  ASN B CB  1 
ATOM 5229 C CG  . ASN D 3 51  ? 193.263 182.046 217.498 1.00 97.11  ? 51  ASN B CG  1 
ATOM 5230 O OD1 . ASN D 3 51  ? 194.019 181.449 216.732 1.00 97.11  ? 51  ASN B OD1 1 
ATOM 5231 N ND2 . ASN D 3 51  ? 192.475 181.414 218.360 1.00 97.11  ? 51  ASN B ND2 1 
ATOM 5232 N N   . ALA D 3 52  ? 195.462 184.293 215.775 1.00 100.72 ? 52  ALA B N   1 
ATOM 5233 C CA  . ALA D 3 52  ? 196.713 184.172 215.037 1.00 100.72 ? 52  ALA B CA  1 
ATOM 5234 C C   . ALA D 3 52  ? 197.095 182.721 214.768 1.00 100.72 ? 52  ALA B C   1 
ATOM 5235 O O   . ALA D 3 52  ? 197.538 182.390 213.664 1.00 100.72 ? 52  ALA B O   1 
ATOM 5236 C CB  . ALA D 3 52  ? 197.839 184.875 215.798 1.00 100.72 ? 52  ALA B CB  1 
ATOM 5237 N N   . ALA D 3 53  ? 196.934 181.849 215.766 1.00 97.62  ? 53  ALA B N   1 
ATOM 5238 C CA  . ALA D 3 53  ? 197.394 180.470 215.629 1.00 97.62  ? 53  ALA B CA  1 
ATOM 5239 C C   . ALA D 3 53  ? 196.649 179.735 214.522 1.00 97.62  ? 53  ALA B C   1 
ATOM 5240 O O   . ALA D 3 53  ? 197.262 179.004 213.735 1.00 97.62  ? 53  ALA B O   1 
ATOM 5241 C CB  . ALA D 3 53  ? 197.238 179.733 216.958 1.00 97.62  ? 53  ALA B CB  1 
ATOM 5242 N N   . ILE D 3 54  ? 195.331 179.916 214.443 1.00 89.99  ? 54  ILE B N   1 
ATOM 5243 C CA  . ILE D 3 54  ? 194.537 179.155 213.485 1.00 89.99  ? 54  ILE B CA  1 
ATOM 5244 C C   . ILE D 3 54  ? 194.840 179.595 212.059 1.00 89.99  ? 54  ILE B C   1 
ATOM 5245 O O   . ILE D 3 54  ? 194.909 178.766 211.144 1.00 89.99  ? 54  ILE B O   1 
ATOM 5246 C CB  . ILE D 3 54  ? 193.041 179.280 213.816 1.00 89.99  ? 54  ILE B CB  1 
ATOM 5247 C CG1 . ILE D 3 54  ? 192.783 178.723 215.213 1.00 89.99  ? 54  ILE B CG1 1 
ATOM 5248 C CG2 . ILE D 3 54  ? 192.198 178.557 212.776 1.00 89.99  ? 54  ILE B CG2 1 
ATOM 5249 C CD1 . ILE D 3 54  ? 192.596 177.230 215.232 1.00 89.99  ? 54  ILE B CD1 1 
ATOM 5250 N N   . LEU D 3 55  ? 195.029 180.900 211.847 1.00 97.70  ? 55  LEU B N   1 
ATOM 5251 C CA  . LEU D 3 55  ? 195.285 181.400 210.500 1.00 97.70  ? 55  LEU B CA  1 
ATOM 5252 C C   . LEU D 3 55  ? 196.518 180.742 209.890 1.00 97.70  ? 55  LEU B C   1 
ATOM 5253 O O   . LEU D 3 55  ? 196.579 180.530 208.674 1.00 97.70  ? 55  LEU B O   1 
ATOM 5254 C CB  . LEU D 3 55  ? 195.438 182.921 210.526 1.00 97.70  ? 55  LEU B CB  1 
ATOM 5255 C CG  . LEU D 3 55  ? 195.398 183.636 209.173 1.00 97.70  ? 55  LEU B CG  1 
ATOM 5256 C CD1 . LEU D 3 55  ? 194.181 183.206 208.374 1.00 97.70  ? 55  LEU B CD1 1 
ATOM 5257 C CD2 . LEU D 3 55  ? 195.405 185.141 209.366 1.00 97.70  ? 55  LEU B CD2 1 
ATOM 5258 N N   . LYS D 3 56  ? 197.511 180.410 210.720 1.00 100.83 ? 56  LYS B N   1 
ATOM 5259 C CA  . LYS D 3 56  ? 198.652 179.644 210.227 1.00 100.83 ? 56  LYS B CA  1 
ATOM 5260 C C   . LYS D 3 56  ? 198.227 178.256 209.769 1.00 100.83 ? 56  LYS B C   1 
ATOM 5261 O O   . LYS D 3 56  ? 198.648 177.794 208.703 1.00 100.83 ? 56  LYS B O   1 
ATOM 5262 C CB  . LYS D 3 56  ? 199.734 179.535 211.303 1.00 100.83 ? 56  LYS B CB  1 
ATOM 5263 C CG  . LYS D 3 56  ? 199.823 180.711 212.256 1.00 100.83 ? 56  LYS B CG  1 
ATOM 5264 C CD  . LYS D 3 56  ? 200.088 182.007 211.512 1.00 100.83 ? 56  LYS B CD  1 
ATOM 5265 C CE  . LYS D 3 56  ? 201.394 181.936 210.734 1.00 100.83 ? 56  LYS B CE  1 
ATOM 5266 N NZ  . LYS D 3 56  ? 202.569 181.814 211.640 1.00 100.83 ? 56  LYS B NZ  1 
ATOM 5267 N N   . LYS D 3 57  ? 197.394 177.578 210.561 1.00 99.98  ? 57  LYS B N   1 
ATOM 5268 C CA  . LYS D 3 57  ? 196.976 176.225 210.208 1.00 99.98  ? 57  LYS B CA  1 
ATOM 5269 C C   . LYS D 3 57  ? 196.188 176.218 208.906 1.00 99.98  ? 57  LYS B C   1 
ATOM 5270 O O   . LYS D 3 57  ? 196.390 175.346 208.053 1.00 99.98  ? 57  LYS B O   1 
ATOM 5271 C CB  . LYS D 3 57  ? 196.148 175.622 211.342 1.00 99.98  ? 57  LYS B CB  1 
ATOM 5272 C CG  . LYS D 3 57  ? 196.911 175.463 212.646 1.00 99.98  ? 57  LYS B CG  1 
ATOM 5273 C CD  . LYS D 3 57  ? 197.966 174.377 212.554 1.00 99.98  ? 57  LYS B CD  1 
ATOM 5274 C CE  . LYS D 3 57  ? 198.630 174.147 213.902 1.00 99.98  ? 57  LYS B CE  1 
ATOM 5275 N NZ  . LYS D 3 57  ? 199.594 173.014 213.865 1.00 99.98  ? 57  LYS B NZ  1 
ATOM 5276 N N   . VAL D 3 58  ? 195.286 177.186 208.735 1.00 100.86 ? 58  VAL B N   1 
ATOM 5277 C CA  . VAL D 3 58  ? 194.541 177.298 207.486 1.00 100.86 ? 58  VAL B CA  1 
ATOM 5278 C C   . VAL D 3 58  ? 195.476 177.616 206.328 1.00 100.86 ? 58  VAL B C   1 
ATOM 5279 O O   . VAL D 3 58  ? 195.396 176.997 205.260 1.00 100.86 ? 58  VAL B O   1 
ATOM 5280 C CB  . VAL D 3 58  ? 193.432 178.356 207.622 1.00 100.86 ? 58  VAL B CB  1 
ATOM 5281 C CG1 . VAL D 3 58  ? 192.458 178.249 206.466 1.00 100.86 ? 58  VAL B CG1 1 
ATOM 5282 C CG2 . VAL D 3 58  ? 192.703 178.186 208.941 1.00 100.86 ? 58  VAL B CG2 1 
ATOM 5283 N N   . ILE D 3 59  ? 196.379 178.581 206.517 1.00 105.23 ? 59  ILE B N   1 
ATOM 5284 C CA  . ILE D 3 59  ? 197.285 178.960 205.437 1.00 105.23 ? 59  ILE B CA  1 
ATOM 5285 C C   . ILE D 3 59  ? 198.288 177.846 205.166 1.00 105.23 ? 59  ILE B C   1 
ATOM 5286 O O   . ILE D 3 59  ? 198.760 177.679 204.035 1.00 105.23 ? 59  ILE B O   1 
ATOM 5287 C CB  . ILE D 3 59  ? 197.972 180.304 205.753 1.00 105.23 ? 59  ILE B CB  1 
ATOM 5288 C CG1 . ILE D 3 59  ? 198.197 181.096 204.465 1.00 105.23 ? 59  ILE B CG1 1 
ATOM 5289 C CG2 . ILE D 3 59  ? 199.285 180.102 206.493 1.00 105.23 ? 59  ILE B CG2 1 
ATOM 5290 C CD1 . ILE D 3 59  ? 196.938 181.315 203.657 1.00 105.23 ? 59  ILE B CD1 1 
ATOM 5291 N N   . GLN D 3 60  ? 198.628 177.062 206.193 1.00 106.07 ? 60  GLN B N   1 
ATOM 5292 C CA  . GLN D 3 60  ? 199.488 175.903 205.978 1.00 106.07 ? 60  GLN B CA  1 
ATOM 5293 C C   . GLN D 3 60  ? 198.789 174.869 205.107 1.00 106.07 ? 60  GLN B C   1 
ATOM 5294 O O   . GLN D 3 60  ? 199.402 174.271 204.216 1.00 106.07 ? 60  GLN B O   1 
ATOM 5295 C CB  . GLN D 3 60  ? 199.904 175.294 207.316 1.00 106.07 ? 60  GLN B CB  1 
ATOM 5296 C CG  . GLN D 3 60  ? 201.273 174.634 207.294 1.00 106.07 ? 60  GLN B CG  1 
ATOM 5297 C CD  . GLN D 3 60  ? 201.958 174.667 208.645 1.00 106.07 ? 60  GLN B CD  1 
ATOM 5298 O OE1 . GLN D 3 60  ? 202.222 175.736 209.194 1.00 106.07 ? 60  GLN B OE1 1 
ATOM 5299 N NE2 . GLN D 3 60  ? 202.253 173.492 209.187 1.00 106.07 ? 60  GLN B NE2 1 
ATOM 5300 N N   . TRP D 3 61  ? 197.497 174.645 205.354 1.00 102.33 ? 61  TRP B N   1 
ATOM 5301 C CA  . TRP D 3 61  ? 196.730 173.736 204.511 1.00 102.33 ? 61  TRP B CA  1 
ATOM 5302 C C   . TRP D 3 61  ? 196.605 174.276 203.093 1.00 102.33 ? 61  TRP B C   1 
ATOM 5303 O O   . TRP D 3 61  ? 196.672 173.514 202.121 1.00 102.33 ? 61  TRP B O   1 
ATOM 5304 C CB  . TRP D 3 61  ? 195.349 173.499 205.116 1.00 102.33 ? 61  TRP B CB  1 
ATOM 5305 C CG  . TRP D 3 61  ? 194.564 172.440 204.415 1.00 102.33 ? 61  TRP B CG  1 
ATOM 5306 C CD1 . TRP D 3 61  ? 194.525 171.112 204.721 1.00 102.33 ? 61  TRP B CD1 1 
ATOM 5307 C CD2 . TRP D 3 61  ? 193.698 172.619 203.289 1.00 102.33 ? 61  TRP B CD2 1 
ATOM 5308 N NE1 . TRP D 3 61  ? 193.690 170.452 203.854 1.00 102.33 ? 61  TRP B NE1 1 
ATOM 5309 C CE2 . TRP D 3 61  ? 193.169 171.355 202.966 1.00 102.33 ? 61  TRP B CE2 1 
ATOM 5310 C CE3 . TRP D 3 61  ? 193.319 173.725 202.523 1.00 102.33 ? 61  TRP B CE3 1 
ATOM 5311 C CZ2 . TRP D 3 61  ? 192.280 171.167 201.910 1.00 102.33 ? 61  TRP B CZ2 1 
ATOM 5312 C CZ3 . TRP D 3 61  ? 192.438 173.536 201.476 1.00 102.33 ? 61  TRP B CZ3 1 
ATOM 5313 C CH2 . TRP D 3 61  ? 191.929 172.267 201.178 1.00 102.33 ? 61  TRP B CH2 1 
ATOM 5314 N N   . CYS D 3 62  ? 196.414 175.589 202.956 1.00 111.19 ? 62  CYS B N   1 
ATOM 5315 C CA  . CYS D 3 62  ? 196.286 176.180 201.629 1.00 111.19 ? 62  CYS B CA  1 
ATOM 5316 C C   . CYS D 3 62  ? 197.598 176.128 200.858 1.00 111.19 ? 62  CYS B C   1 
ATOM 5317 O O   . CYS D 3 62  ? 197.585 176.058 199.624 1.00 111.19 ? 62  CYS B O   1 
ATOM 5318 C CB  . CYS D 3 62  ? 195.793 177.622 201.743 1.00 111.19 ? 62  CYS B CB  1 
ATOM 5319 S SG  . CYS D 3 62  ? 194.024 177.827 201.442 1.00 111.19 ? 62  CYS B SG  1 
ATOM 5320 N N   . THR D 3 63  ? 198.735 176.170 201.558 1.00 112.97 ? 63  THR B N   1 
ATOM 5321 C CA  . THR D 3 63  ? 200.021 176.123 200.870 1.00 112.97 ? 63  THR B CA  1 
ATOM 5322 C C   . THR D 3 63  ? 200.230 174.787 200.168 1.00 112.97 ? 63  THR B C   1 
ATOM 5323 O O   . THR D 3 63  ? 200.682 174.749 199.018 1.00 112.97 ? 63  THR B O   1 
ATOM 5324 C CB  . THR D 3 63  ? 201.160 176.395 201.852 1.00 112.97 ? 63  THR B CB  1 
ATOM 5325 O OG1 . THR D 3 63  ? 200.890 175.738 203.095 1.00 112.97 ? 63  THR B OG1 1 
ATOM 5326 C CG2 . THR D 3 63  ? 201.310 177.890 202.094 1.00 112.97 ? 63  THR B CG2 1 
ATOM 5327 N N   . HIS D 3 64  ? 199.907 173.681 200.840 1.00 114.62 ? 64  HIS B N   1 
ATOM 5328 C CA  . HIS D 3 64  ? 200.093 172.372 200.224 1.00 114.62 ? 64  HIS B CA  1 
ATOM 5329 C C   . HIS D 3 64  ? 199.028 172.093 199.171 1.00 114.62 ? 64  HIS B C   1 
ATOM 5330 O O   . HIS D 3 64  ? 199.337 171.580 198.089 1.00 114.62 ? 64  HIS B O   1 
ATOM 5331 C CB  . HIS D 3 64  ? 200.081 171.281 201.291 1.00 114.62 ? 64  HIS B CB  1 
ATOM 5332 C CG  . HIS D 3 64  ? 200.182 169.896 200.735 1.00 114.62 ? 64  HIS B CG  1 
ATOM 5333 N ND1 . HIS D 3 64  ? 199.074 169.129 200.445 1.00 114.62 ? 64  HIS B ND1 1 
ATOM 5334 C CD2 . HIS D 3 64  ? 201.258 169.138 200.419 1.00 114.62 ? 64  HIS B CD2 1 
ATOM 5335 C CE1 . HIS D 3 64  ? 199.463 167.958 199.973 1.00 114.62 ? 64  HIS B CE1 1 
ATOM 5336 N NE2 . HIS D 3 64  ? 200.784 167.938 199.947 1.00 114.62 ? 64  HIS B NE2 1 
ATOM 5337 N N   . HIS D 3 65  ? 197.776 172.421 199.465 1.00 116.04 ? 65  HIS B N   1 
ATOM 5338 C CA  . HIS D 3 65  ? 196.660 172.084 198.583 1.00 116.04 ? 65  HIS B CA  1 
ATOM 5339 C C   . HIS D 3 65  ? 196.322 173.263 197.672 1.00 116.04 ? 65  HIS B C   1 
ATOM 5340 O O   . HIS D 3 65  ? 195.232 173.832 197.715 1.00 116.04 ? 65  HIS B O   1 
ATOM 5341 C CB  . HIS D 3 65  ? 195.450 171.656 199.407 1.00 116.04 ? 65  HIS B CB  1 
ATOM 5342 C CG  . HIS D 3 65  ? 195.432 170.198 199.743 1.00 116.04 ? 65  HIS B CG  1 
ATOM 5343 N ND1 . HIS D 3 65  ? 194.911 169.713 200.923 1.00 116.04 ? 65  HIS B ND1 1 
ATOM 5344 C CD2 . HIS D 3 65  ? 195.884 169.119 199.061 1.00 116.04 ? 65  HIS B CD2 1 
ATOM 5345 C CE1 . HIS D 3 65  ? 195.033 168.398 200.949 1.00 116.04 ? 65  HIS B CE1 1 
ATOM 5346 N NE2 . HIS D 3 65  ? 195.621 168.012 199.832 1.00 116.04 ? 65  HIS B NE2 1 
ATOM 5347 N N   . LYS D 3 66  ? 197.288 173.626 196.832 1.00 115.99 ? 66  LYS B N   1 
ATOM 5348 C CA  . LYS D 3 66  ? 197.123 174.716 195.883 1.00 115.99 ? 66  LYS B CA  1 
ATOM 5349 C C   . LYS D 3 66  ? 197.132 174.253 194.433 1.00 115.99 ? 66  LYS B C   1 
ATOM 5350 O O   . LYS D 3 66  ? 196.828 175.051 193.540 1.00 115.99 ? 66  LYS B O   1 
ATOM 5351 C CB  . LYS D 3 66  ? 198.210 175.775 196.103 1.00 115.99 ? 66  LYS B CB  1 
ATOM 5352 C CG  . LYS D 3 66  ? 199.628 175.252 195.973 1.00 115.99 ? 66  LYS B CG  1 
ATOM 5353 C CD  . LYS D 3 66  ? 200.649 176.356 196.191 1.00 115.99 ? 66  LYS B CD  1 
ATOM 5354 C CE  . LYS D 3 66  ? 202.067 175.841 196.006 1.00 115.99 ? 66  LYS B CE  1 
ATOM 5355 N NZ  . LYS D 3 66  ? 202.294 175.311 194.634 1.00 115.99 ? 66  LYS B NZ  1 
ATOM 5356 N N   . ASP D 3 67  ? 197.471 172.990 194.171 1.00 124.47 ? 67  ASP B N   1 
ATOM 5357 C CA  . ASP D 3 67  ? 197.422 172.426 192.827 1.00 124.47 ? 67  ASP B CA  1 
ATOM 5358 C C   . ASP D 3 67  ? 196.319 171.387 192.670 1.00 124.47 ? 67  ASP B C   1 
ATOM 5359 O O   . ASP D 3 67  ? 196.530 170.375 191.991 1.00 124.47 ? 67  ASP B O   1 
ATOM 5360 C CB  . ASP D 3 67  ? 198.770 171.801 192.444 1.00 124.47 ? 67  ASP B CB  1 
ATOM 5361 C CG  . ASP D 3 67  ? 199.951 172.695 192.772 1.00 124.47 ? 67  ASP B CG  1 
ATOM 5362 O OD1 . ASP D 3 67  ? 199.736 173.852 193.181 1.00 124.47 ? 67  ASP B OD1 1 
ATOM 5363 O OD2 . ASP D 3 67  ? 201.103 172.236 192.618 1.00 124.47 ? 67  ASP B OD2 1 
ATOM 5364 N N   . ASP D 3 68  ? 195.162 171.598 193.284 1.00 125.15 ? 68  ASP B N   1 
ATOM 5365 C CA  . ASP D 3 68  ? 194.077 170.630 193.174 1.00 125.15 ? 68  ASP B CA  1 
ATOM 5366 C C   . ASP D 3 68  ? 193.007 171.146 192.218 1.00 125.15 ? 68  ASP B C   1 
ATOM 5367 O O   . ASP D 3 68  ? 192.312 172.117 192.540 1.00 125.15 ? 68  ASP B O   1 
ATOM 5368 C CB  . ASP D 3 68  ? 193.459 170.358 194.544 1.00 125.15 ? 68  ASP B CB  1 
ATOM 5369 C CG  . ASP D 3 68  ? 194.491 169.993 195.590 1.00 125.15 ? 68  ASP B CG  1 
ATOM 5370 O OD1 . ASP D 3 68  ? 195.695 169.959 195.261 1.00 125.15 ? 68  ASP B OD1 1 
ATOM 5371 O OD2 . ASP D 3 68  ? 194.094 169.744 196.748 1.00 125.15 ? 68  ASP B OD2 1 
ATOM 5372 N N   . PRO D 3 69  ? 192.851 170.544 191.043 1.00 130.43 ? 69  PRO B N   1 
ATOM 5373 C CA  . PRO D 3 69  ? 191.741 170.918 190.159 1.00 130.43 ? 69  PRO B CA  1 
ATOM 5374 C C   . PRO D 3 69  ? 190.407 170.606 190.811 1.00 130.43 ? 69  PRO B C   1 
ATOM 5375 O O   . PRO D 3 69  ? 190.157 169.460 191.216 1.00 130.43 ? 69  PRO B O   1 
ATOM 5376 C CB  . PRO D 3 69  ? 191.957 170.047 188.910 1.00 130.43 ? 69  PRO B CB  1 
ATOM 5377 C CG  . PRO D 3 69  ? 193.164 169.206 189.175 1.00 130.43 ? 69  PRO B CG  1 
ATOM 5378 C CD  . PRO D 3 69  ? 193.885 169.763 190.348 1.00 130.43 ? 69  PRO B CD  1 
ATOM 5379 N N   . PRO D 3 70  ? 189.525 171.592 190.936 1.00 138.31 ? 70  PRO B N   1 
ATOM 5380 C CA  . PRO D 3 70  ? 188.200 171.334 191.502 1.00 138.31 ? 70  PRO B CA  1 
ATOM 5381 C C   . PRO D 3 70  ? 187.274 170.736 190.459 1.00 138.31 ? 70  PRO B C   1 
ATOM 5382 O O   . PRO D 3 70  ? 186.977 171.373 189.437 1.00 138.31 ? 70  PRO B O   1 
ATOM 5383 C CB  . PRO D 3 70  ? 187.727 172.726 191.942 1.00 138.31 ? 70  PRO B CB  1 
ATOM 5384 C CG  . PRO D 3 70  ? 188.432 173.665 191.024 1.00 138.31 ? 70  PRO B CG  1 
ATOM 5385 C CD  . PRO D 3 70  ? 189.744 173.021 190.648 1.00 138.31 ? 70  PRO B CD  1 
ATOM 5386 N N   . PRO D 3 71  ? 186.793 169.504 190.677 1.00 138.50 ? 71  PRO B N   1 
ATOM 5387 C CA  . PRO D 3 71  ? 185.915 168.830 189.718 1.00 138.50 ? 71  PRO B CA  1 
ATOM 5388 C C   . PRO D 3 71  ? 184.445 169.191 189.910 1.00 138.50 ? 71  PRO B C   1 
ATOM 5389 O O   . PRO D 3 71  ? 183.613 168.739 189.123 1.00 138.50 ? 71  PRO B O   1 
ATOM 5390 C CB  . PRO D 3 71  ? 186.156 167.349 190.011 1.00 138.50 ? 71  PRO B CB  1 
ATOM 5391 C CG  . PRO D 3 71  ? 186.562 167.305 191.460 1.00 138.50 ? 71  PRO B CG  1 
ATOM 5392 C CD  . PRO D 3 71  ? 187.030 168.682 191.876 1.00 138.50 ? 71  PRO B CD  1 
ATOM 5393 N N   . ASN D 3 77  ? 183.587 164.810 191.667 1.00 148.44 ? 77  ASN B N   1 
ATOM 5394 C CA  . ASN D 3 77  ? 182.947 165.817 192.504 1.00 148.44 ? 77  ASN B CA  1 
ATOM 5395 C C   . ASN D 3 77  ? 181.816 165.207 193.326 1.00 148.44 ? 77  ASN B C   1 
ATOM 5396 O O   . ASN D 3 77  ? 181.638 165.540 194.498 1.00 148.44 ? 77  ASN B O   1 
ATOM 5397 C CB  . ASN D 3 77  ? 182.414 166.967 191.648 1.00 148.44 ? 77  ASN B CB  1 
ATOM 5398 C CG  . ASN D 3 77  ? 182.045 168.183 192.473 1.00 148.44 ? 77  ASN B CG  1 
ATOM 5399 O OD1 . ASN D 3 77  ? 180.874 168.411 192.775 1.00 148.44 ? 77  ASN B OD1 1 
ATOM 5400 N ND2 . ASN D 3 77  ? 183.047 168.973 192.843 1.00 148.44 ? 77  ASN B ND2 1 
ATOM 5401 N N   . LYS D 3 78  ? 181.052 164.311 192.701 1.00 142.23 ? 78  LYS B N   1 
ATOM 5402 C CA  . LYS D 3 78  ? 179.939 163.628 193.361 1.00 142.23 ? 78  LYS B CA  1 
ATOM 5403 C C   . LYS D 3 78  ? 180.214 162.129 193.291 1.00 142.23 ? 78  LYS B C   1 
ATOM 5404 O O   . LYS D 3 78  ? 179.872 161.475 192.301 1.00 142.23 ? 78  LYS B O   1 
ATOM 5405 C CB  . LYS D 3 78  ? 178.606 163.979 192.713 1.00 142.23 ? 78  LYS B CB  1 
ATOM 5406 C CG  . LYS D 3 78  ? 178.534 165.391 192.158 1.00 142.23 ? 78  LYS B CG  1 
ATOM 5407 C CD  . LYS D 3 78  ? 177.415 165.525 191.140 1.00 142.23 ? 78  LYS B CD  1 
ATOM 5408 C CE  . LYS D 3 78  ? 177.567 164.510 190.020 1.00 142.23 ? 78  LYS B CE  1 
ATOM 5409 N NZ  . LYS D 3 78  ? 178.898 164.610 189.359 1.00 142.23 ? 78  LYS B NZ  1 
ATOM 5410 N N   . GLU D 3 79  ? 180.831 161.594 194.340 1.00 141.31 ? 79  GLU B N   1 
ATOM 5411 C CA  . GLU D 3 79  ? 181.171 160.182 194.418 1.00 141.31 ? 79  GLU B CA  1 
ATOM 5412 C C   . GLU D 3 79  ? 180.619 159.603 195.711 1.00 141.31 ? 79  GLU B C   1 
ATOM 5413 O O   . GLU D 3 79  ? 180.219 160.340 196.617 1.00 141.31 ? 79  GLU B O   1 
ATOM 5414 C CB  . GLU D 3 79  ? 182.690 159.955 194.362 1.00 141.31 ? 79  GLU B CB  1 
ATOM 5415 C CG  . GLU D 3 79  ? 183.421 160.790 193.322 1.00 141.31 ? 79  GLU B CG  1 
ATOM 5416 C CD  . GLU D 3 79  ? 183.857 162.140 193.861 1.00 141.31 ? 79  GLU B CD  1 
ATOM 5417 O OE1 . GLU D 3 79  ? 183.613 162.412 195.055 1.00 141.31 ? 79  GLU B OE1 1 
ATOM 5418 O OE2 . GLU D 3 79  ? 184.443 162.928 193.090 1.00 141.31 ? 79  GLU B OE2 1 
ATOM 5419 N N   . LYS D 3 80  ? 180.591 158.273 195.784 1.00 128.88 ? 80  LYS B N   1 
ATOM 5420 C CA  . LYS D 3 80  ? 180.224 157.602 197.023 1.00 128.88 ? 80  LYS B CA  1 
ATOM 5421 C C   . LYS D 3 80  ? 181.223 157.980 198.108 1.00 128.88 ? 80  LYS B C   1 
ATOM 5422 O O   . LYS D 3 80  ? 182.436 157.921 197.885 1.00 128.88 ? 80  LYS B O   1 
ATOM 5423 C CB  . LYS D 3 80  ? 180.180 156.085 196.827 1.00 128.88 ? 80  LYS B CB  1 
ATOM 5424 C CG  . LYS D 3 80  ? 180.019 155.294 198.115 1.00 128.88 ? 80  LYS B CG  1 
ATOM 5425 C CD  . LYS D 3 80  ? 180.774 153.977 198.060 1.00 128.88 ? 80  LYS B CD  1 
ATOM 5426 C CE  . LYS D 3 80  ? 182.244 154.199 197.744 1.00 128.88 ? 80  LYS B CE  1 
ATOM 5427 N NZ  . LYS D 3 80  ? 182.920 155.002 198.801 1.00 128.88 ? 80  LYS B NZ  1 
ATOM 5428 N N   . ARG D 3 81  ? 180.723 158.383 199.277 1.00 116.41 ? 81  ARG B N   1 
ATOM 5429 C CA  . ARG D 3 81  ? 181.575 158.862 200.359 1.00 116.41 ? 81  ARG B CA  1 
ATOM 5430 C C   . ARG D 3 81  ? 182.566 157.781 200.775 1.00 116.41 ? 81  ARG B C   1 
ATOM 5431 O O   . ARG D 3 81  ? 182.194 156.612 200.918 1.00 116.41 ? 81  ARG B O   1 
ATOM 5432 C CB  . ARG D 3 81  ? 180.727 159.307 201.555 1.00 116.41 ? 81  ARG B CB  1 
ATOM 5433 C CG  . ARG D 3 81  ? 179.964 160.616 201.348 1.00 116.41 ? 81  ARG B CG  1 
ATOM 5434 C CD  . ARG D 3 81  ? 178.678 160.413 200.553 1.00 116.41 ? 81  ARG B CD  1 
ATOM 5435 N NE  . ARG D 3 81  ? 178.184 161.657 199.973 1.00 116.41 ? 81  ARG B NE  1 
ATOM 5436 C CZ  . ARG D 3 81  ? 177.065 162.265 200.343 1.00 116.41 ? 81  ARG B CZ  1 
ATOM 5437 N NH1 . ARG D 3 81  ? 176.287 161.766 201.289 1.00 116.41 ? 81  ARG B NH1 1 
ATOM 5438 N NH2 . ARG D 3 81  ? 176.717 163.401 199.746 1.00 116.41 ? 81  ARG B NH2 1 
ATOM 5439 N N   . THR D 3 82  ? 183.828 158.162 200.974 1.00 120.54 ? 82  THR B N   1 
ATOM 5440 C CA  . THR D 3 82  ? 184.881 157.181 201.208 1.00 120.54 ? 82  THR B CA  1 
ATOM 5441 C C   . THR D 3 82  ? 185.852 157.638 202.290 1.00 120.54 ? 82  THR B C   1 
ATOM 5442 O O   . THR D 3 82  ? 185.563 158.572 203.044 1.00 120.54 ? 82  THR B O   1 
ATOM 5443 C CB  . THR D 3 82  ? 185.643 156.897 199.912 1.00 120.54 ? 82  THR B CB  1 
ATOM 5444 O OG1 . THR D 3 82  ? 186.793 156.091 200.199 1.00 120.54 ? 82  THR B OG1 1 
ATOM 5445 C CG2 . THR D 3 82  ? 186.091 158.198 199.261 1.00 120.54 ? 82  THR B CG2 1 
ATOM 5446 N N   . ASP D 3 83  ? 187.006 156.976 202.370 1.00 131.87 ? 83  ASP B N   1 
ATOM 5447 C CA  . ASP D 3 83  ? 187.991 157.251 203.408 1.00 131.87 ? 83  ASP B CA  1 
ATOM 5448 C C   . ASP D 3 83  ? 189.383 157.472 202.823 1.00 131.87 ? 83  ASP B C   1 
ATOM 5449 O O   . ASP D 3 83  ? 190.383 157.056 203.417 1.00 131.87 ? 83  ASP B O   1 
ATOM 5450 C CB  . ASP D 3 83  ? 188.005 156.110 204.429 1.00 131.87 ? 83  ASP B CB  1 
ATOM 5451 C CG  . ASP D 3 83  ? 188.579 154.824 203.863 1.00 131.87 ? 83  ASP B CG  1 
ATOM 5452 O OD1 . ASP D 3 83  ? 188.202 154.455 202.730 1.00 131.87 ? 83  ASP B OD1 1 
ATOM 5453 O OD2 . ASP D 3 83  ? 189.399 154.181 204.551 1.00 131.87 ? 83  ASP B OD2 1 
ATOM 5454 N N   . ASP D 3 84  ? 189.458 158.126 201.662 1.00 128.08 ? 84  ASP B N   1 
ATOM 5455 C CA  . ASP D 3 84  ? 190.752 158.356 201.024 1.00 128.08 ? 84  ASP B CA  1 
ATOM 5456 C C   . ASP D 3 84  ? 191.679 159.171 201.921 1.00 128.08 ? 84  ASP B C   1 
ATOM 5457 O O   . ASP D 3 84  ? 192.773 158.711 202.271 1.00 128.08 ? 84  ASP B O   1 
ATOM 5458 C CB  . ASP D 3 84  ? 190.549 159.031 199.663 1.00 128.08 ? 84  ASP B CB  1 
ATOM 5459 C CG  . ASP D 3 84  ? 189.695 160.282 199.745 1.00 128.08 ? 84  ASP B CG  1 
ATOM 5460 O OD1 . ASP D 3 84  ? 190.063 161.214 200.490 1.00 128.08 ? 84  ASP B OD1 1 
ATOM 5461 O OD2 . ASP D 3 84  ? 188.648 160.329 199.067 1.00 128.08 ? 84  ASP B OD2 1 
ATOM 5462 N N   . ILE D 3 85  ? 191.249 160.371 202.313 1.00 120.49 ? 85  ILE B N   1 
ATOM 5463 C CA  . ILE D 3 85  ? 191.932 161.262 203.261 1.00 120.49 ? 85  ILE B CA  1 
ATOM 5464 C C   . ILE D 3 85  ? 193.441 161.269 203.010 1.00 120.49 ? 85  ILE B C   1 
ATOM 5465 O O   . ILE D 3 85  ? 194.195 160.591 203.723 1.00 120.49 ? 85  ILE B O   1 
ATOM 5466 C CB  . ILE D 3 85  ? 191.556 160.937 204.726 1.00 120.49 ? 85  ILE B CB  1 
ATOM 5467 C CG1 . ILE D 3 85  ? 192.209 161.935 205.689 1.00 120.49 ? 85  ILE B CG1 1 
ATOM 5468 C CG2 . ILE D 3 85  ? 191.832 159.481 205.131 1.00 120.49 ? 85  ILE B CG2 1 
ATOM 5469 C CD1 . ILE D 3 85  ? 191.975 161.613 207.146 1.00 120.49 ? 85  ILE B CD1 1 
ATOM 5470 N N   . PRO D 3 86  ? 193.915 161.985 201.966 1.00 118.26 ? 86  PRO B N   1 
ATOM 5471 C CA  . PRO D 3 86  ? 195.342 161.967 201.601 1.00 118.26 ? 86  PRO B CA  1 
ATOM 5472 C C   . PRO D 3 86  ? 196.316 162.055 202.767 1.00 118.26 ? 86  PRO B C   1 
ATOM 5473 O O   . PRO D 3 86  ? 195.999 162.610 203.821 1.00 118.26 ? 86  PRO B O   1 
ATOM 5474 C CB  . PRO D 3 86  ? 195.471 163.202 200.700 1.00 118.26 ? 86  PRO B CB  1 
ATOM 5475 C CG  . PRO D 3 86  ? 194.062 163.474 200.178 1.00 118.26 ? 86  PRO B CG  1 
ATOM 5476 C CD  . PRO D 3 86  ? 193.106 162.528 200.865 1.00 118.26 ? 86  PRO B CD  1 
ATOM 5477 N N   . VAL D 3 87  ? 197.518 161.516 202.564 1.00 117.33 ? 87  VAL B N   1 
ATOM 5478 C CA  . VAL D 3 87  ? 198.494 161.277 203.624 1.00 117.33 ? 87  VAL B CA  1 
ATOM 5479 C C   . VAL D 3 87  ? 198.787 162.540 204.429 1.00 117.33 ? 87  VAL B C   1 
ATOM 5480 O O   . VAL D 3 87  ? 199.007 162.473 205.643 1.00 117.33 ? 87  VAL B O   1 
ATOM 5481 C CB  . VAL D 3 87  ? 199.789 160.695 203.023 1.00 117.33 ? 87  VAL B CB  1 
ATOM 5482 C CG1 . VAL D 3 87  ? 201.004 161.057 203.867 1.00 117.33 ? 87  VAL B CG1 1 
ATOM 5483 C CG2 . VAL D 3 87  ? 199.669 159.187 202.863 1.00 117.33 ? 87  VAL B CG2 1 
ATOM 5484 N N   . TRP D 3 88  ? 198.768 163.702 203.774 1.00 116.49 ? 88  TRP B N   1 
ATOM 5485 C CA  . TRP D 3 88  ? 199.157 164.942 204.437 1.00 116.49 ? 88  TRP B CA  1 
ATOM 5486 C C   . TRP D 3 88  ? 198.179 165.387 205.521 1.00 116.49 ? 88  TRP B C   1 
ATOM 5487 O O   . TRP D 3 88  ? 198.583 165.964 206.537 1.00 116.49 ? 88  TRP B O   1 
ATOM 5488 C CB  . TRP D 3 88  ? 199.321 166.060 203.401 1.00 116.49 ? 88  TRP B CB  1 
ATOM 5489 C CG  . TRP D 3 88  ? 199.916 167.349 203.947 1.00 116.49 ? 88  TRP B CG  1 
ATOM 5490 C CD1 . TRP D 3 88  ? 199.604 168.616 203.546 1.00 116.49 ? 88  TRP B CD1 1 
ATOM 5491 C CD2 . TRP D 3 88  ? 200.921 167.493 204.968 1.00 116.49 ? 88  TRP B CD2 1 
ATOM 5492 N NE1 . TRP D 3 88  ? 200.337 169.536 204.252 1.00 116.49 ? 88  TRP B NE1 1 
ATOM 5493 C CE2 . TRP D 3 88  ? 201.154 168.874 205.130 1.00 116.49 ? 88  TRP B CE2 1 
ATOM 5494 C CE3 . TRP D 3 88  ? 201.644 166.593 205.759 1.00 116.49 ? 88  TRP B CE3 1 
ATOM 5495 C CZ2 . TRP D 3 88  ? 202.075 169.373 206.049 1.00 116.49 ? 88  TRP B CZ2 1 
ATOM 5496 C CZ3 . TRP D 3 88  ? 202.553 167.091 206.671 1.00 116.49 ? 88  TRP B CZ3 1 
ATOM 5497 C CH2 . TRP D 3 88  ? 202.762 168.467 206.808 1.00 116.49 ? 88  TRP B CH2 1 
ATOM 5498 N N   . ASP D 3 89  ? 196.883 165.140 205.316 1.00 118.08 ? 89  ASP B N   1 
ATOM 5499 C CA  . ASP D 3 89  ? 195.876 165.792 206.148 1.00 118.08 ? 89  ASP B CA  1 
ATOM 5500 C C   . ASP D 3 89  ? 195.919 165.307 207.592 1.00 118.08 ? 89  ASP B C   1 
ATOM 5501 O O   . ASP D 3 89  ? 195.927 166.121 208.522 1.00 118.08 ? 89  ASP B O   1 
ATOM 5502 C CB  . ASP D 3 89  ? 194.484 165.592 205.551 1.00 118.08 ? 89  ASP B CB  1 
ATOM 5503 C CG  . ASP D 3 89  ? 194.497 165.574 204.039 1.00 118.08 ? 89  ASP B CG  1 
ATOM 5504 O OD1 . ASP D 3 89  ? 194.807 166.623 203.440 1.00 118.08 ? 89  ASP B OD1 1 
ATOM 5505 O OD2 . ASP D 3 89  ? 194.215 164.515 203.447 1.00 118.08 ? 89  ASP B OD2 1 
ATOM 5506 N N   . GLN D 3 90  ? 195.940 163.990 207.808 1.00 114.47 ? 90  GLN B N   1 
ATOM 5507 C CA  . GLN D 3 90  ? 195.936 163.483 209.177 1.00 114.47 ? 90  GLN B CA  1 
ATOM 5508 C C   . GLN D 3 90  ? 197.241 163.814 209.892 1.00 114.47 ? 90  GLN B C   1 
ATOM 5509 O O   . GLN D 3 90  ? 197.251 164.022 211.110 1.00 114.47 ? 90  GLN B O   1 
ATOM 5510 C CB  . GLN D 3 90  ? 195.644 161.976 209.209 1.00 114.47 ? 90  GLN B CB  1 
ATOM 5511 C CG  . GLN D 3 90  ? 196.643 161.039 208.526 1.00 114.47 ? 90  GLN B CG  1 
ATOM 5512 C CD  . GLN D 3 90  ? 196.705 161.190 207.015 1.00 114.47 ? 90  GLN B CD  1 
ATOM 5513 O OE1 . GLN D 3 90  ? 196.468 162.265 206.470 1.00 114.47 ? 90  GLN B OE1 1 
ATOM 5514 N NE2 . GLN D 3 90  ? 197.028 160.099 206.330 1.00 114.47 ? 90  GLN B NE2 1 
ATOM 5515 N N   . GLU D 3 91  ? 198.355 163.881 209.155 1.00 116.07 ? 91  GLU B N   1 
ATOM 5516 C CA  . GLU D 3 91  ? 199.575 164.418 209.751 1.00 116.07 ? 91  GLU B CA  1 
ATOM 5517 C C   . GLU D 3 91  ? 199.386 165.860 210.193 1.00 116.07 ? 91  GLU B C   1 
ATOM 5518 O O   . GLU D 3 91  ? 199.822 166.239 211.287 1.00 116.07 ? 91  GLU B O   1 
ATOM 5519 C CB  . GLU D 3 91  ? 200.751 164.330 208.777 1.00 116.07 ? 91  GLU B CB  1 
ATOM 5520 C CG  . GLU D 3 91  ? 200.888 163.021 208.023 1.00 116.07 ? 91  GLU B CG  1 
ATOM 5521 C CD  . GLU D 3 91  ? 200.605 161.808 208.886 1.00 116.07 ? 91  GLU B CD  1 
ATOM 5522 O OE1 . GLU D 3 91  ? 201.212 161.689 209.972 1.00 116.07 ? 91  GLU B OE1 1 
ATOM 5523 O OE2 . GLU D 3 91  ? 199.788 160.961 208.472 1.00 116.07 ? 91  GLU B OE2 1 
ATOM 5524 N N   . PHE D 3 92  ? 198.737 166.672 209.363 1.00 110.13 ? 92  PHE B N   1 
ATOM 5525 C CA  . PHE D 3 92  ? 198.389 168.034 209.746 1.00 110.13 ? 92  PHE B CA  1 
ATOM 5526 C C   . PHE D 3 92  ? 197.420 167.987 210.927 1.00 110.13 ? 92  PHE B C   1 
ATOM 5527 O O   . PHE D 3 92  ? 197.577 168.721 211.908 1.00 110.13 ? 92  PHE B O   1 
ATOM 5528 C CB  . PHE D 3 92  ? 197.808 168.750 208.508 1.00 110.13 ? 92  PHE B CB  1 
ATOM 5529 C CG  . PHE D 3 92  ? 197.054 170.044 208.775 1.00 110.13 ? 92  PHE B CG  1 
ATOM 5530 C CD1 . PHE D 3 92  ? 197.215 170.778 209.939 1.00 110.13 ? 92  PHE B CD1 1 
ATOM 5531 C CD2 . PHE D 3 92  ? 196.174 170.522 207.818 1.00 110.13 ? 92  PHE B CD2 1 
ATOM 5532 C CE1 . PHE D 3 92  ? 196.514 171.950 210.144 1.00 110.13 ? 92  PHE B CE1 1 
ATOM 5533 C CE2 . PHE D 3 92  ? 195.471 171.690 208.019 1.00 110.13 ? 92  PHE B CE2 1 
ATOM 5534 C CZ  . PHE D 3 92  ? 195.642 172.406 209.182 1.00 110.13 ? 92  PHE B CZ  1 
ATOM 5535 N N   . LEU D 3 93  ? 196.457 167.065 210.878 1.00 105.27 ? 93  LEU B N   1 
ATOM 5536 C CA  . LEU D 3 93  ? 195.316 167.082 211.786 1.00 105.27 ? 93  LEU B CA  1 
ATOM 5537 C C   . LEU D 3 93  ? 195.558 166.397 213.128 1.00 105.27 ? 93  LEU B C   1 
ATOM 5538 O O   . LEU D 3 93  ? 194.666 166.408 213.982 1.00 105.27 ? 93  LEU B O   1 
ATOM 5539 C CB  . LEU D 3 93  ? 194.103 166.437 211.110 1.00 105.27 ? 93  LEU B CB  1 
ATOM 5540 C CG  . LEU D 3 93  ? 193.115 167.350 210.379 1.00 105.27 ? 93  LEU B CG  1 
ATOM 5541 C CD1 . LEU D 3 93  ? 193.831 168.463 209.632 1.00 105.27 ? 93  LEU B CD1 1 
ATOM 5542 C CD2 . LEU D 3 93  ? 192.255 166.543 209.426 1.00 105.27 ? 93  LEU B CD2 1 
ATOM 5543 N N   . LYS D 3 94  ? 196.730 165.797 213.347 1.00 107.83 ? 94  LYS B N   1 
ATOM 5544 C CA  . LYS D 3 94  ? 196.965 165.257 214.682 1.00 107.83 ? 94  LYS B CA  1 
ATOM 5545 C C   . LYS D 3 94  ? 197.206 166.408 215.643 1.00 107.83 ? 94  LYS B C   1 
ATOM 5546 O O   . LYS D 3 94  ? 198.355 166.776 215.909 1.00 107.83 ? 94  LYS B O   1 
ATOM 5547 C CB  . LYS D 3 94  ? 198.154 164.293 214.736 1.00 107.83 ? 94  LYS B CB  1 
ATOM 5548 C CG  . LYS D 3 94  ? 198.034 163.042 213.898 1.00 107.83 ? 94  LYS B CG  1 
ATOM 5549 C CD  . LYS D 3 94  ? 199.403 162.410 213.710 1.00 107.83 ? 94  LYS B CD  1 
ATOM 5550 C CE  . LYS D 3 94  ? 200.338 163.319 212.939 1.00 107.83 ? 94  LYS B CE  1 
ATOM 5551 N NZ  . LYS D 3 94  ? 201.303 162.550 212.108 1.00 107.83 ? 94  LYS B NZ  1 
ATOM 5552 N N   . VAL D 3 95  ? 196.127 166.976 216.172 1.00 98.81  ? 95  VAL B N   1 
ATOM 5553 C CA  . VAL D 3 95  ? 196.209 168.086 217.112 1.00 98.81  ? 95  VAL B CA  1 
ATOM 5554 C C   . VAL D 3 95  ? 195.151 167.792 218.169 1.00 98.81  ? 95  VAL B C   1 
ATOM 5555 O O   . VAL D 3 95  ? 194.268 166.955 217.948 1.00 98.81  ? 95  VAL B O   1 
ATOM 5556 C CB  . VAL D 3 95  ? 195.984 169.441 216.405 1.00 98.81  ? 95  VAL B CB  1 
ATOM 5557 C CG1 . VAL D 3 95  ? 196.003 170.611 217.385 1.00 98.81  ? 95  VAL B CG1 1 
ATOM 5558 C CG2 . VAL D 3 95  ? 197.002 169.659 215.292 1.00 98.81  ? 95  VAL B CG2 1 
ATOM 5559 N N   . ASP D 3 96  ? 195.222 168.465 219.313 1.00 102.45 ? 96  ASP B N   1 
ATOM 5560 C CA  . ASP D 3 96  ? 194.265 168.263 220.387 1.00 102.45 ? 96  ASP B CA  1 
ATOM 5561 C C   . ASP D 3 96  ? 192.844 168.545 219.905 1.00 102.45 ? 96  ASP B C   1 
ATOM 5562 O O   . ASP D 3 96  ? 192.625 169.153 218.854 1.00 102.45 ? 96  ASP B O   1 
ATOM 5563 C CB  . ASP D 3 96  ? 194.611 169.148 221.587 1.00 102.45 ? 96  ASP B CB  1 
ATOM 5564 C CG  . ASP D 3 96  ? 194.879 170.590 221.195 1.00 102.45 ? 96  ASP B CG  1 
ATOM 5565 O OD1 . ASP D 3 96  ? 194.367 171.034 220.148 1.00 102.45 ? 96  ASP B OD1 1 
ATOM 5566 O OD2 . ASP D 3 96  ? 195.605 171.282 221.940 1.00 102.45 ? 96  ASP B OD2 1 
ATOM 5567 N N   . GLN D 3 97  ? 191.871 168.086 220.695 1.00 100.18 ? 97  GLN B N   1 
ATOM 5568 C CA  . GLN D 3 97  ? 190.480 168.115 220.254 1.00 100.18 ? 97  GLN B CA  1 
ATOM 5569 C C   . GLN D 3 97  ? 190.006 169.536 219.969 1.00 100.18 ? 97  GLN B C   1 
ATOM 5570 O O   . GLN D 3 97  ? 189.342 169.784 218.956 1.00 100.18 ? 97  GLN B O   1 
ATOM 5571 C CB  . GLN D 3 97  ? 189.587 167.461 221.308 1.00 100.18 ? 97  GLN B CB  1 
ATOM 5572 C CG  . GLN D 3 97  ? 188.592 166.460 220.751 1.00 100.18 ? 97  GLN B CG  1 
ATOM 5573 C CD  . GLN D 3 97  ? 187.677 165.896 221.819 1.00 100.18 ? 97  GLN B CD  1 
ATOM 5574 O OE1 . GLN D 3 97  ? 186.738 166.558 222.261 1.00 100.18 ? 97  GLN B OE1 1 
ATOM 5575 N NE2 . GLN D 3 97  ? 187.948 164.667 222.242 1.00 100.18 ? 97  GLN B NE2 1 
ATOM 5576 N N   . GLY D 3 98  ? 190.357 170.484 220.839 1.00 96.76  ? 98  GLY B N   1 
ATOM 5577 C CA  . GLY D 3 98  ? 189.797 171.824 220.732 1.00 96.76  ? 98  GLY B CA  1 
ATOM 5578 C C   . GLY D 3 98  ? 190.162 172.525 219.438 1.00 96.76  ? 98  GLY B C   1 
ATOM 5579 O O   . GLY D 3 98  ? 189.311 173.136 218.787 1.00 96.76  ? 98  GLY B O   1 
ATOM 5580 N N   . THR D 3 99  ? 191.436 172.448 219.046 1.00 95.31  ? 99  THR B N   1 
ATOM 5581 C CA  . THR D 3 99  ? 191.889 173.173 217.862 1.00 95.31  ? 99  THR B CA  1 
ATOM 5582 C C   . THR D 3 99  ? 191.234 172.637 216.595 1.00 95.31  ? 99  THR B C   1 
ATOM 5583 O O   . THR D 3 99  ? 190.919 173.406 215.679 1.00 95.31  ? 99  THR B O   1 
ATOM 5584 C CB  . THR D 3 99  ? 193.411 173.107 217.754 1.00 95.31  ? 99  THR B CB  1 
ATOM 5585 O OG1 . THR D 3 99  ? 193.997 173.576 218.975 1.00 95.31  ? 99  THR B OG1 1 
ATOM 5586 C CG2 . THR D 3 99  ? 193.905 173.970 216.604 1.00 95.31  ? 99  THR B CG2 1 
ATOM 5587 N N   . LEU D 3 100 ? 191.028 171.321 216.521 1.00 95.58  ? 100 LEU B N   1 
ATOM 5588 C CA  . LEU D 3 100 ? 190.348 170.742 215.366 1.00 95.58  ? 100 LEU B CA  1 
ATOM 5589 C C   . LEU D 3 100 ? 188.960 171.344 215.195 1.00 95.58  ? 100 LEU B C   1 
ATOM 5590 O O   . LEU D 3 100 ? 188.527 171.619 214.070 1.00 95.58  ? 100 LEU B O   1 
ATOM 5591 C CB  . LEU D 3 100 ? 190.285 169.218 215.519 1.00 95.58  ? 100 LEU B CB  1 
ATOM 5592 C CG  . LEU D 3 100 ? 189.575 168.298 214.516 1.00 95.58  ? 100 LEU B CG  1 
ATOM 5593 C CD1 . LEU D 3 100 ? 190.112 166.887 214.672 1.00 95.58  ? 100 LEU B CD1 1 
ATOM 5594 C CD2 . LEU D 3 100 ? 188.067 168.280 214.716 1.00 95.58  ? 100 LEU B CD2 1 
ATOM 5595 N N   . PHE D 3 101 ? 188.251 171.554 216.303 1.00 100.26 ? 101 PHE B N   1 
ATOM 5596 C CA  . PHE D 3 101 ? 186.951 172.212 216.250 1.00 100.26 ? 101 PHE B CA  1 
ATOM 5597 C C   . PHE D 3 101 ? 187.079 173.652 215.772 1.00 100.26 ? 101 PHE B C   1 
ATOM 5598 O O   . PHE D 3 101 ? 186.223 174.142 215.028 1.00 100.26 ? 101 PHE B O   1 
ATOM 5599 C CB  . PHE D 3 101 ? 186.299 172.147 217.628 1.00 100.26 ? 101 PHE B CB  1 
ATOM 5600 C CG  . PHE D 3 101 ? 186.227 170.759 218.183 1.00 100.26 ? 101 PHE B CG  1 
ATOM 5601 C CD1 . PHE D 3 101 ? 185.994 169.682 217.344 1.00 100.26 ? 101 PHE B CD1 1 
ATOM 5602 C CD2 . PHE D 3 101 ? 186.474 170.519 219.524 1.00 100.26 ? 101 PHE B CD2 1 
ATOM 5603 C CE1 . PHE D 3 101 ? 185.947 168.397 217.839 1.00 100.26 ? 101 PHE B CE1 1 
ATOM 5604 C CE2 . PHE D 3 101 ? 186.441 169.230 220.025 1.00 100.26 ? 101 PHE B CE2 1 
ATOM 5605 C CZ  . PHE D 3 101 ? 186.170 168.169 219.179 1.00 100.26 ? 101 PHE B CZ  1 
ATOM 5606 N N   . GLU D 3 102 ? 188.142 174.344 216.184 1.00 95.31  ? 102 GLU B N   1 
ATOM 5607 C CA  . GLU D 3 102 ? 188.343 175.718 215.737 1.00 95.31  ? 102 GLU B CA  1 
ATOM 5608 C C   . GLU D 3 102 ? 188.603 175.781 214.238 1.00 95.31  ? 102 GLU B C   1 
ATOM 5609 O O   . GLU D 3 102 ? 188.232 176.760 213.580 1.00 95.31  ? 102 GLU B O   1 
ATOM 5610 C CB  . GLU D 3 102 ? 189.496 176.356 216.508 1.00 95.31  ? 102 GLU B CB  1 
ATOM 5611 C CG  . GLU D 3 102 ? 189.154 176.752 217.927 1.00 95.31  ? 102 GLU B CG  1 
ATOM 5612 C CD  . GLU D 3 102 ? 190.348 177.305 218.678 1.00 95.31  ? 102 GLU B CD  1 
ATOM 5613 O OE1 . GLU D 3 102 ? 191.493 177.005 218.281 1.00 95.31  ? 102 GLU B OE1 1 
ATOM 5614 O OE2 . GLU D 3 102 ? 190.143 178.041 219.666 1.00 95.31  ? 102 GLU B OE2 1 
ATOM 5615 N N   . LEU D 3 103 ? 189.245 174.753 213.680 1.00 86.56  ? 103 LEU B N   1 
ATOM 5616 C CA  . LEU D 3 103 ? 189.415 174.697 212.232 1.00 86.56  ? 103 LEU B CA  1 
ATOM 5617 C C   . LEU D 3 103 ? 188.073 174.549 211.529 1.00 86.56  ? 103 LEU B C   1 
ATOM 5618 O O   . LEU D 3 103 ? 187.894 175.045 210.411 1.00 86.56  ? 103 LEU B O   1 
ATOM 5619 C CB  . LEU D 3 103 ? 190.349 173.551 211.850 1.00 86.56  ? 103 LEU B CB  1 
ATOM 5620 C CG  . LEU D 3 103 ? 191.754 173.591 212.447 1.00 86.56  ? 103 LEU B CG  1 
ATOM 5621 C CD1 . LEU D 3 103 ? 192.326 172.189 212.563 1.00 86.56  ? 103 LEU B CD1 1 
ATOM 5622 C CD2 . LEU D 3 103 ? 192.660 174.475 211.608 1.00 86.56  ? 103 LEU B CD2 1 
ATOM 5623 N N   . ILE D 3 104 ? 187.121 173.867 212.168 1.00 81.68  ? 104 ILE B N   1 
ATOM 5624 C CA  . ILE D 3 104 ? 185.792 173.716 211.583 1.00 81.68  ? 104 ILE B CA  1 
ATOM 5625 C C   . ILE D 3 104 ? 185.143 175.081 211.394 1.00 81.68  ? 104 ILE B C   1 
ATOM 5626 O O   . ILE D 3 104 ? 184.576 175.377 210.335 1.00 81.68  ? 104 ILE B O   1 
ATOM 5627 C CB  . ILE D 3 104 ? 184.924 172.794 212.458 1.00 81.68  ? 104 ILE B CB  1 
ATOM 5628 C CG1 . ILE D 3 104 ? 185.202 171.328 212.129 1.00 81.68  ? 104 ILE B CG1 1 
ATOM 5629 C CG2 . ILE D 3 104 ? 183.456 173.108 212.272 1.00 81.68  ? 104 ILE B CG2 1 
ATOM 5630 C CD1 . ILE D 3 104 ? 185.006 170.988 210.677 1.00 81.68  ? 104 ILE B CD1 1 
ATOM 5631 N N   . LEU D 3 105 ? 185.223 175.936 212.416 1.00 75.78  ? 105 LEU B N   1 
ATOM 5632 C CA  . LEU D 3 105 ? 184.691 177.289 212.283 1.00 75.78  ? 105 LEU B CA  1 
ATOM 5633 C C   . LEU D 3 105 ? 185.467 178.084 211.243 1.00 75.78  ? 105 LEU B C   1 
ATOM 5634 O O   . LEU D 3 105 ? 184.871 178.781 210.416 1.00 75.78  ? 105 LEU B O   1 
ATOM 5635 C CB  . LEU D 3 105 ? 184.715 178.012 213.630 1.00 75.78  ? 105 LEU B CB  1 
ATOM 5636 C CG  . LEU D 3 105 ? 183.666 177.630 214.678 1.00 75.78  ? 105 LEU B CG  1 
ATOM 5637 C CD1 . LEU D 3 105 ? 182.271 177.671 214.077 1.00 75.78  ? 105 LEU B CD1 1 
ATOM 5638 C CD2 . LEU D 3 105 ? 183.948 176.278 215.303 1.00 75.78  ? 105 LEU B CD2 1 
ATOM 5639 N N   . ALA D 3 106 ? 186.798 177.986 211.263 1.00 73.70  ? 106 ALA B N   1 
ATOM 5640 C CA  . ALA D 3 106 ? 187.603 178.715 210.289 1.00 73.70  ? 106 ALA B CA  1 
ATOM 5641 C C   . ALA D 3 106 ? 187.312 178.244 208.871 1.00 73.70  ? 106 ALA B C   1 
ATOM 5642 O O   . ALA D 3 106 ? 187.216 179.061 207.948 1.00 73.70  ? 106 ALA B O   1 
ATOM 5643 C CB  . ALA D 3 106 ? 189.088 178.563 210.614 1.00 73.70  ? 106 ALA B CB  1 
ATOM 5644 N N   . ALA D 3 107 ? 187.174 176.932 208.674 1.00 78.88  ? 107 ALA B N   1 
ATOM 5645 C CA  . ALA D 3 107 ? 186.791 176.428 207.361 1.00 78.88  ? 107 ALA B CA  1 
ATOM 5646 C C   . ALA D 3 107 ? 185.384 176.870 206.980 1.00 78.88  ? 107 ALA B C   1 
ATOM 5647 O O   . ALA D 3 107 ? 185.141 177.225 205.822 1.00 78.88  ? 107 ALA B O   1 
ATOM 5648 C CB  . ALA D 3 107 ? 186.897 174.904 207.328 1.00 78.88  ? 107 ALA B CB  1 
ATOM 5649 N N   . ASN D 3 108 ? 184.449 176.850 207.933 1.00 71.51  ? 108 ASN B N   1 
ATOM 5650 C CA  . ASN D 3 108 ? 183.081 177.261 207.640 1.00 71.51  ? 108 ASN B CA  1 
ATOM 5651 C C   . ASN D 3 108 ? 182.968 178.768 207.450 1.00 71.51  ? 108 ASN B C   1 
ATOM 5652 O O   . ASN D 3 108 ? 182.211 179.226 206.588 1.00 71.51  ? 108 ASN B O   1 
ATOM 5653 C CB  . ASN D 3 108 ? 182.145 176.799 208.756 1.00 71.51  ? 108 ASN B CB  1 
ATOM 5654 C CG  . ASN D 3 108 ? 180.693 177.075 208.447 1.00 71.51  ? 108 ASN B CG  1 
ATOM 5655 O OD1 . ASN D 3 108 ? 180.295 177.134 207.285 1.00 71.51  ? 108 ASN B OD1 1 
ATOM 5656 N ND2 . ASN D 3 108 ? 179.889 177.251 209.488 1.00 71.51  ? 108 ASN B ND2 1 
ATOM 5657 N N   . TYR D 3 109 ? 183.706 179.550 208.239 1.00 70.97  ? 109 TYR B N   1 
ATOM 5658 C CA  . TYR D 3 109 ? 183.612 181.003 208.150 1.00 70.97  ? 109 TYR B CA  1 
ATOM 5659 C C   . TYR D 3 109 ? 184.157 181.512 206.821 1.00 70.97  ? 109 TYR B C   1 
ATOM 5660 O O   . TYR D 3 109 ? 183.533 182.356 206.170 1.00 70.97  ? 109 TYR B O   1 
ATOM 5661 C CB  . TYR D 3 109 ? 184.347 181.638 209.336 1.00 70.97  ? 109 TYR B CB  1 
ATOM 5662 C CG  . TYR D 3 109 ? 184.479 183.147 209.324 1.00 70.97  ? 109 TYR B CG  1 
ATOM 5663 C CD1 . TYR D 3 109 ? 185.370 183.791 208.476 1.00 70.97  ? 109 TYR B CD1 1 
ATOM 5664 C CD2 . TYR D 3 109 ? 183.768 183.920 210.226 1.00 70.97  ? 109 TYR B CD2 1 
ATOM 5665 C CE1 . TYR D 3 109 ? 185.500 185.161 208.488 1.00 70.97  ? 109 TYR B CE1 1 
ATOM 5666 C CE2 . TYR D 3 109 ? 183.890 185.287 210.242 1.00 70.97  ? 109 TYR B CE2 1 
ATOM 5667 C CZ  . TYR D 3 109 ? 184.759 185.904 209.377 1.00 70.97  ? 109 TYR B CZ  1 
ATOM 5668 O OH  . TYR D 3 109 ? 184.882 187.273 209.404 1.00 70.97  ? 109 TYR B OH  1 
ATOM 5669 N N   . LEU D 3 110 ? 185.321 181.015 206.403 1.00 75.17  ? 110 LEU B N   1 
ATOM 5670 C CA  . LEU D 3 110 ? 185.896 181.463 205.141 1.00 75.17  ? 110 LEU B CA  1 
ATOM 5671 C C   . LEU D 3 110 ? 185.381 180.674 203.950 1.00 75.17  ? 110 LEU B C   1 
ATOM 5672 O O   . LEU D 3 110 ? 185.694 181.034 202.810 1.00 75.17  ? 110 LEU B O   1 
ATOM 5673 C CB  . LEU D 3 110 ? 187.420 181.368 205.191 1.00 75.17  ? 110 LEU B CB  1 
ATOM 5674 C CG  . LEU D 3 110 ? 188.127 182.327 206.142 1.00 75.17  ? 110 LEU B CG  1 
ATOM 5675 C CD1 . LEU D 3 110 ? 189.625 182.088 206.124 1.00 75.17  ? 110 LEU B CD1 1 
ATOM 5676 C CD2 . LEU D 3 110 ? 187.809 183.747 205.740 1.00 75.17  ? 110 LEU B CD2 1 
ATOM 5677 N N   . ASP D 3 111 ? 184.601 179.623 204.190 1.00 82.56  ? 111 ASP B N   1 
ATOM 5678 C CA  . ASP D 3 111 ? 184.065 178.752 203.147 1.00 82.56  ? 111 ASP B CA  1 
ATOM 5679 C C   . ASP D 3 111 ? 185.236 178.188 202.335 1.00 82.56  ? 111 ASP B C   1 
ATOM 5680 O O   . ASP D 3 111 ? 185.629 178.713 201.289 1.00 82.56  ? 111 ASP B O   1 
ATOM 5681 C CB  . ASP D 3 111 ? 183.030 179.508 202.288 1.00 82.56  ? 111 ASP B CB  1 
ATOM 5682 C CG  . ASP D 3 111 ? 182.648 178.799 200.971 1.00 82.56  ? 111 ASP B CG  1 
ATOM 5683 O OD1 . ASP D 3 111 ? 183.441 178.103 200.316 1.00 82.56  ? 111 ASP B OD1 1 
ATOM 5684 O OD2 . ASP D 3 111 ? 181.480 178.962 200.564 1.00 82.56  ? 111 ASP B OD2 1 
ATOM 5685 N N   . ILE D 3 112 ? 185.878 177.182 202.915 1.00 83.57  ? 112 ILE B N   1 
ATOM 5686 C CA  . ILE D 3 112 ? 186.906 176.404 202.239 1.00 83.57  ? 112 ILE B CA  1 
ATOM 5687 C C   . ILE D 3 112 ? 186.362 174.989 202.128 1.00 83.57  ? 112 ILE B C   1 
ATOM 5688 O O   . ILE D 3 112 ? 186.397 174.222 203.096 1.00 83.57  ? 112 ILE B O   1 
ATOM 5689 C CB  . ILE D 3 112 ? 188.245 176.444 202.982 1.00 83.57  ? 112 ILE B CB  1 
ATOM 5690 C CG1 . ILE D 3 112 ? 188.543 177.869 203.450 1.00 83.57  ? 112 ILE B CG1 1 
ATOM 5691 C CG2 . ILE D 3 112 ? 189.366 175.927 202.086 1.00 83.57  ? 112 ILE B CG2 1 
ATOM 5692 C CD1 . ILE D 3 112 ? 189.994 178.119 203.757 1.00 83.57  ? 112 ILE B CD1 1 
ATOM 5693 N N   . LYS D 3 113 ? 185.851 174.636 200.948 1.00 80.80  ? 113 LYS B N   1 
ATOM 5694 C CA  . LYS D 3 113 ? 185.217 173.334 200.791 1.00 80.80  ? 113 LYS B CA  1 
ATOM 5695 C C   . LYS D 3 113 ? 186.207 172.202 201.030 1.00 80.80  ? 113 LYS B C   1 
ATOM 5696 O O   . LYS D 3 113 ? 185.865 171.200 201.667 1.00 80.80  ? 113 LYS B O   1 
ATOM 5697 C CB  . LYS D 3 113 ? 184.586 173.218 199.407 1.00 80.80  ? 113 LYS B CB  1 
ATOM 5698 C CG  . LYS D 3 113 ? 183.661 172.024 199.274 1.00 80.80  ? 113 LYS B CG  1 
ATOM 5699 C CD  . LYS D 3 113 ? 182.966 171.995 197.930 1.00 80.80  ? 113 LYS B CD  1 
ATOM 5700 C CE  . LYS D 3 113 ? 181.937 170.874 197.880 1.00 80.80  ? 113 LYS B CE  1 
ATOM 5701 N NZ  . LYS D 3 113 ? 182.523 169.523 198.122 1.00 80.80  ? 113 LYS B NZ  1 
ATOM 5702 N N   . GLY D 3 114 ? 187.439 172.345 200.540 1.00 84.21  ? 114 GLY B N   1 
ATOM 5703 C CA  . GLY D 3 114 ? 188.429 171.300 200.750 1.00 84.21  ? 114 GLY B CA  1 
ATOM 5704 C C   . GLY D 3 114 ? 188.764 171.095 202.215 1.00 84.21  ? 114 GLY B C   1 
ATOM 5705 O O   . GLY D 3 114 ? 188.804 169.961 202.702 1.00 84.21  ? 114 GLY B O   1 
ATOM 5706 N N   . LEU D 3 115 ? 189.004 172.188 202.943 1.00 82.87  ? 115 LEU B N   1 
ATOM 5707 C CA  . LEU D 3 115 ? 189.355 172.065 204.354 1.00 82.87  ? 115 LEU B CA  1 
ATOM 5708 C C   . LEU D 3 115 ? 188.164 171.567 205.164 1.00 82.87  ? 115 LEU B C   1 
ATOM 5709 O O   . LEU D 3 115 ? 188.318 170.728 206.059 1.00 82.87  ? 115 LEU B O   1 
ATOM 5710 C CB  . LEU D 3 115 ? 189.861 173.408 204.883 1.00 82.87  ? 115 LEU B CB  1 
ATOM 5711 C CG  . LEU D 3 115 ? 190.728 173.520 206.147 1.00 82.87  ? 115 LEU B CG  1 
ATOM 5712 C CD1 . LEU D 3 115 ? 190.931 174.985 206.476 1.00 82.87  ? 115 LEU B CD1 1 
ATOM 5713 C CD2 . LEU D 3 115 ? 190.194 172.793 207.373 1.00 82.87  ? 115 LEU B CD2 1 
ATOM 5714 N N   . LEU D 3 116 ? 186.966 172.062 204.855 1.00 80.15  ? 116 LEU B N   1 
ATOM 5715 C CA  . LEU D 3 116 ? 185.771 171.592 205.548 1.00 80.15  ? 116 LEU B CA  1 
ATOM 5716 C C   . LEU D 3 116 ? 185.498 170.129 205.225 1.00 80.15  ? 116 LEU B C   1 
ATOM 5717 O O   . LEU D 3 116 ? 184.991 169.378 206.066 1.00 80.15  ? 116 LEU B O   1 
ATOM 5718 C CB  . LEU D 3 116 ? 184.573 172.460 205.168 1.00 80.15  ? 116 LEU B CB  1 
ATOM 5719 C CG  . LEU D 3 116 ? 183.326 172.325 206.040 1.00 80.15  ? 116 LEU B CG  1 
ATOM 5720 C CD1 . LEU D 3 116 ? 183.702 172.191 207.503 1.00 80.15  ? 116 LEU B CD1 1 
ATOM 5721 C CD2 . LEU D 3 116 ? 182.403 173.509 205.827 1.00 80.15  ? 116 LEU B CD2 1 
ATOM 5722 N N   . ASP D 3 117 ? 185.814 169.713 203.998 1.00 90.04  ? 117 ASP B N   1 
ATOM 5723 C CA  . ASP D 3 117 ? 185.617 168.323 203.602 1.00 90.04  ? 117 ASP B CA  1 
ATOM 5724 C C   . ASP D 3 117 ? 186.484 167.385 204.434 1.00 90.04  ? 117 ASP B C   1 
ATOM 5725 O O   . ASP D 3 117 ? 186.022 166.333 204.891 1.00 90.04  ? 117 ASP B O   1 
ATOM 5726 C CB  . ASP D 3 117 ? 185.932 168.161 202.114 1.00 90.04  ? 117 ASP B CB  1 
ATOM 5727 C CG  . ASP D 3 117 ? 185.257 166.956 201.500 1.00 90.04  ? 117 ASP B CG  1 
ATOM 5728 O OD1 . ASP D 3 117 ? 184.101 166.670 201.869 1.00 90.04  ? 117 ASP B OD1 1 
ATOM 5729 O OD2 . ASP D 3 117 ? 185.883 166.296 200.645 1.00 90.04  ? 117 ASP B OD2 1 
ATOM 5730 N N   . VAL D 3 118 ? 187.750 167.751 204.638 1.00 85.59  ? 118 VAL B N   1 
ATOM 5731 C CA  . VAL D 3 118 ? 188.693 166.843 205.285 1.00 85.59  ? 118 VAL B CA  1 
ATOM 5732 C C   . VAL D 3 118 ? 188.416 166.738 206.778 1.00 85.59  ? 118 VAL B C   1 
ATOM 5733 O O   . VAL D 3 118 ? 188.351 165.635 207.335 1.00 85.59  ? 118 VAL B O   1 
ATOM 5734 C CB  . VAL D 3 118 ? 190.137 167.299 205.013 1.00 85.59  ? 118 VAL B CB  1 
ATOM 5735 C CG1 . VAL D 3 118 ? 191.099 166.510 205.873 1.00 85.59  ? 118 VAL B CG1 1 
ATOM 5736 C CG2 . VAL D 3 118 ? 190.472 167.138 203.542 1.00 85.59  ? 118 VAL B CG2 1 
ATOM 5737 N N   . THR D 3 119 ? 188.253 167.879 207.452 1.00 85.75  ? 119 THR B N   1 
ATOM 5738 C CA  . THR D 3 119 ? 188.108 167.867 208.905 1.00 85.75  ? 119 THR B CA  1 
ATOM 5739 C C   . THR D 3 119 ? 186.844 167.135 209.332 1.00 85.75  ? 119 THR B C   1 
ATOM 5740 O O   . THR D 3 119 ? 186.839 166.435 210.351 1.00 85.75  ? 119 THR B O   1 
ATOM 5741 C CB  . THR D 3 119 ? 188.105 169.294 209.446 1.00 85.75  ? 119 THR B CB  1 
ATOM 5742 O OG1 . THR D 3 119 ? 187.320 170.127 208.586 1.00 85.75  ? 119 THR B OG1 1 
ATOM 5743 C CG2 . THR D 3 119 ? 189.522 169.835 209.517 1.00 85.75  ? 119 THR B CG2 1 
ATOM 5744 N N   . CYS D 3 120 ? 185.761 167.288 208.570 1.00 89.91  ? 120 CYS B N   1 
ATOM 5745 C CA  . CYS D 3 120 ? 184.527 166.586 208.900 1.00 89.91  ? 120 CYS B CA  1 
ATOM 5746 C C   . CYS D 3 120 ? 184.690 165.078 208.747 1.00 89.91  ? 120 CYS B C   1 
ATOM 5747 O O   . CYS D 3 120 ? 183.999 164.303 209.418 1.00 89.91  ? 120 CYS B O   1 
ATOM 5748 C CB  . CYS D 3 120 ? 183.388 167.103 208.025 1.00 89.91  ? 120 CYS B CB  1 
ATOM 5749 S SG  . CYS D 3 120 ? 182.815 168.753 208.479 1.00 89.91  ? 120 CYS B SG  1 
ATOM 5750 N N   . LYS D 3 121 ? 185.596 164.643 207.867 1.00 93.60  ? 121 LYS B N   1 
ATOM 5751 C CA  . LYS D 3 121 ? 185.843 163.213 207.704 1.00 93.60  ? 121 LYS B CA  1 
ATOM 5752 C C   . LYS D 3 121 ? 186.365 162.587 208.991 1.00 93.60  ? 121 LYS B C   1 
ATOM 5753 O O   . LYS D 3 121 ? 185.886 161.528 209.411 1.00 93.60  ? 121 LYS B O   1 
ATOM 5754 C CB  . LYS D 3 121 ? 186.830 162.975 206.562 1.00 93.60  ? 121 LYS B CB  1 
ATOM 5755 C CG  . LYS D 3 121 ? 186.199 162.938 205.187 1.00 93.60  ? 121 LYS B CG  1 
ATOM 5756 C CD  . LYS D 3 121 ? 187.207 162.518 204.133 1.00 93.60  ? 121 LYS B CD  1 
ATOM 5757 C CE  . LYS D 3 121 ? 186.532 162.290 202.792 1.00 93.60  ? 121 LYS B CE  1 
ATOM 5758 N NZ  . LYS D 3 121 ? 187.499 161.851 201.750 1.00 93.60  ? 121 LYS B NZ  1 
ATOM 5759 N N   . THR D 3 122 ? 187.350 163.224 209.627 1.00 89.95  ? 122 THR B N   1 
ATOM 5760 C CA  . THR D 3 122 ? 187.928 162.665 210.845 1.00 89.95  ? 122 THR B CA  1 
ATOM 5761 C C   . THR D 3 122 ? 186.913 162.658 211.980 1.00 89.95  ? 122 THR B C   1 
ATOM 5762 O O   . THR D 3 122 ? 186.887 161.733 212.800 1.00 89.95  ? 122 THR B O   1 
ATOM 5763 C CB  . THR D 3 122 ? 189.177 163.449 211.241 1.00 89.95  ? 122 THR B CB  1 
ATOM 5764 O OG1 . THR D 3 122 ? 188.805 164.558 212.068 1.00 89.95  ? 122 THR B OG1 1 
ATOM 5765 C CG2 . THR D 3 122 ? 189.881 163.963 210.003 1.00 89.95  ? 122 THR B CG2 1 
ATOM 5766 N N   . VAL D 3 123 ? 186.071 163.691 212.048 1.00 92.24  ? 123 VAL B N   1 
ATOM 5767 C CA  . VAL D 3 123 ? 184.999 163.706 213.038 1.00 92.24  ? 123 VAL B CA  1 
ATOM 5768 C C   . VAL D 3 123 ? 184.052 162.538 212.802 1.00 92.24  ? 123 VAL B C   1 
ATOM 5769 O O   . VAL D 3 123 ? 183.647 161.845 213.744 1.00 92.24  ? 123 VAL B O   1 
ATOM 5770 C CB  . VAL D 3 123 ? 184.259 165.055 213.005 1.00 92.24  ? 123 VAL B CB  1 
ATOM 5771 C CG1 . VAL D 3 123 ? 182.932 164.953 213.737 1.00 92.24  ? 123 VAL B CG1 1 
ATOM 5772 C CG2 . VAL D 3 123 ? 185.123 166.144 213.613 1.00 92.24  ? 123 VAL B CG2 1 
ATOM 5773 N N   . ALA D 3 124 ? 183.690 162.297 211.540 1.00 96.80  ? 124 ALA B N   1 
ATOM 5774 C CA  . ALA D 3 124 ? 182.868 161.137 211.215 1.00 96.80  ? 124 ALA B CA  1 
ATOM 5775 C C   . ALA D 3 124 ? 183.595 159.837 211.538 1.00 96.80  ? 124 ALA B C   1 
ATOM 5776 O O   . ALA D 3 124 ? 182.988 158.894 212.058 1.00 96.80  ? 124 ALA B O   1 
ATOM 5777 C CB  . ALA D 3 124 ? 182.464 161.177 209.742 1.00 96.80  ? 124 ALA B CB  1 
ATOM 5778 N N   . ASN D 3 125 ? 184.893 159.767 211.233 1.00 96.80  ? 125 ASN B N   1 
ATOM 5779 C CA  . ASN D 3 125 ? 185.669 158.583 211.585 1.00 96.80  ? 125 ASN B CA  1 
ATOM 5780 C C   . ASN D 3 125 ? 185.739 158.391 213.094 1.00 96.80  ? 125 ASN B C   1 
ATOM 5781 O O   . ASN D 3 125 ? 185.635 157.259 213.578 1.00 96.80  ? 125 ASN B O   1 
ATOM 5782 C CB  . ASN D 3 125 ? 187.074 158.676 210.992 1.00 96.80  ? 125 ASN B CB  1 
ATOM 5783 C CG  . ASN D 3 125 ? 187.193 157.956 209.664 1.00 96.80  ? 125 ASN B CG  1 
ATOM 5784 O OD1 . ASN D 3 125 ? 186.235 157.348 209.188 1.00 96.80  ? 125 ASN B OD1 1 
ATOM 5785 N ND2 . ASN D 3 125 ? 188.372 158.021 209.058 1.00 96.80  ? 125 ASN B ND2 1 
ATOM 5786 N N   . MET D 3 126 ? 185.919 159.477 213.849 1.00 96.32  ? 126 MET B N   1 
ATOM 5787 C CA  . MET D 3 126 ? 185.850 159.381 215.302 1.00 96.32  ? 126 MET B CA  1 
ATOM 5788 C C   . MET D 3 126 ? 184.447 159.016 215.763 1.00 96.32  ? 126 MET B C   1 
ATOM 5789 O O   . MET D 3 126 ? 184.283 158.331 216.779 1.00 96.32  ? 126 MET B O   1 
ATOM 5790 C CB  . MET D 3 126 ? 186.301 160.697 215.936 1.00 96.32  ? 126 MET B CB  1 
ATOM 5791 C CG  . MET D 3 126 ? 187.809 160.896 215.928 1.00 96.32  ? 126 MET B CG  1 
ATOM 5792 S SD  . MET D 3 126 ? 188.364 162.387 216.779 1.00 96.32  ? 126 MET B SD  1 
ATOM 5793 C CE  . MET D 3 126 ? 186.870 162.890 217.626 1.00 96.32  ? 126 MET B CE  1 
ATOM 5794 N N   . ILE D 3 127 ? 183.425 159.465 215.033 1.00 97.84  ? 127 ILE B N   1 
ATOM 5795 C CA  . ILE D 3 127 ? 182.054 159.067 215.328 1.00 97.84  ? 127 ILE B CA  1 
ATOM 5796 C C   . ILE D 3 127 ? 181.841 157.588 215.022 1.00 97.84  ? 127 ILE B C   1 
ATOM 5797 O O   . ILE D 3 127 ? 181.188 156.876 215.795 1.00 97.84  ? 127 ILE B O   1 
ATOM 5798 C CB  . ILE D 3 127 ? 181.074 159.951 214.535 1.00 97.84  ? 127 ILE B CB  1 
ATOM 5799 C CG1 . ILE D 3 127 ? 180.756 161.230 215.309 1.00 97.84  ? 127 ILE B CG1 1 
ATOM 5800 C CG2 . ILE D 3 127 ? 179.793 159.192 214.210 1.00 97.84  ? 127 ILE B CG2 1 
ATOM 5801 C CD1 . ILE D 3 127 ? 179.773 161.033 216.426 1.00 97.84  ? 127 ILE B CD1 1 
ATOM 5802 N N   . LYS D 3 128 ? 182.395 157.106 213.912 1.00 100.10 ? 128 LYS B N   1 
ATOM 5803 C CA  . LYS D 3 128 ? 182.177 155.732 213.485 1.00 100.10 ? 128 LYS B CA  1 
ATOM 5804 C C   . LYS D 3 128 ? 182.759 154.750 214.494 1.00 100.10 ? 128 LYS B C   1 
ATOM 5805 O O   . LYS D 3 128 ? 183.697 155.068 215.230 1.00 100.10 ? 128 LYS B O   1 
ATOM 5806 C CB  . LYS D 3 128 ? 182.807 155.513 212.108 1.00 100.10 ? 128 LYS B CB  1 
ATOM 5807 C CG  . LYS D 3 128 ? 182.362 154.245 211.402 1.00 100.10 ? 128 LYS B CG  1 
ATOM 5808 C CD  . LYS D 3 128 ? 180.858 154.226 211.205 1.00 100.10 ? 128 LYS B CD  1 
ATOM 5809 C CE  . LYS D 3 128 ? 180.305 152.817 211.327 1.00 100.10 ? 128 LYS B CE  1 
ATOM 5810 N NZ  . LYS D 3 128 ? 180.164 152.399 212.746 1.00 100.10 ? 128 LYS B NZ  1 
ATOM 5811 N N   . GLY D 3 129 ? 182.188 153.551 214.527 1.00 108.87 ? 129 GLY B N   1 
ATOM 5812 C CA  . GLY D 3 129 ? 182.645 152.504 215.425 1.00 108.87 ? 129 GLY B CA  1 
ATOM 5813 C C   . GLY D 3 129 ? 182.404 152.786 216.891 1.00 108.87 ? 129 GLY B C   1 
ATOM 5814 O O   . GLY D 3 129 ? 183.219 152.393 217.736 1.00 108.87 ? 129 GLY B O   1 
ATOM 5815 N N   . LYS D 3 130 ? 181.304 153.462 217.218 1.00 108.73 ? 130 LYS B N   1 
ATOM 5816 C CA  . LYS D 3 130 ? 180.926 153.731 218.597 1.00 108.73 ? 130 LYS B CA  1 
ATOM 5817 C C   . LYS D 3 130 ? 179.425 153.521 218.739 1.00 108.73 ? 130 LYS B C   1 
ATOM 5818 O O   . LYS D 3 130 ? 178.694 153.412 217.750 1.00 108.73 ? 130 LYS B O   1 
ATOM 5819 C CB  . LYS D 3 130 ? 181.315 155.151 219.028 1.00 108.73 ? 130 LYS B CB  1 
ATOM 5820 C CG  . LYS D 3 130 ? 182.710 155.596 218.616 1.00 108.73 ? 130 LYS B CG  1 
ATOM 5821 C CD  . LYS D 3 130 ? 183.747 155.202 219.653 1.00 108.73 ? 130 LYS B CD  1 
ATOM 5822 C CE  . LYS D 3 130 ? 185.129 155.090 219.032 1.00 108.73 ? 130 LYS B CE  1 
ATOM 5823 N NZ  . LYS D 3 130 ? 185.173 154.057 217.962 1.00 108.73 ? 130 LYS B NZ  1 
ATOM 5824 N N   . THR D 3 131 ? 178.963 153.466 219.985 1.00 107.27 ? 131 THR B N   1 
ATOM 5825 C CA  . THR D 3 131 ? 177.537 153.396 220.246 1.00 107.27 ? 131 THR B CA  1 
ATOM 5826 C C   . THR D 3 131 ? 176.998 154.787 220.563 1.00 107.27 ? 131 THR B C   1 
ATOM 5827 O O   . THR D 3 131 ? 177.745 155.636 221.062 1.00 107.27 ? 131 THR B O   1 
ATOM 5828 C CB  . THR D 3 131 ? 177.226 152.442 221.410 1.00 107.27 ? 131 THR B CB  1 
ATOM 5829 O OG1 . THR D 3 131 ? 175.815 152.423 221.661 1.00 107.27 ? 131 THR B OG1 1 
ATOM 5830 C CG2 . THR D 3 131 ? 177.953 152.867 222.668 1.00 107.27 ? 131 THR B CG2 1 
ATOM 5831 N N   . PRO D 3 132 ? 175.724 155.058 220.242 1.00 106.44 ? 132 PRO B N   1 
ATOM 5832 C CA  . PRO D 3 132 ? 175.154 156.393 220.472 1.00 106.44 ? 132 PRO B CA  1 
ATOM 5833 C C   . PRO D 3 132 ? 175.466 156.996 221.833 1.00 106.44 ? 132 PRO B C   1 
ATOM 5834 O O   . PRO D 3 132 ? 175.927 158.138 221.915 1.00 106.44 ? 132 PRO B O   1 
ATOM 5835 C CB  . PRO D 3 132 ? 173.645 156.149 220.325 1.00 106.44 ? 132 PRO B CB  1 
ATOM 5836 C CG  . PRO D 3 132 ? 173.507 154.823 219.585 1.00 106.44 ? 132 PRO B CG  1 
ATOM 5837 C CD  . PRO D 3 132 ? 174.880 154.269 219.332 1.00 106.44 ? 132 PRO B CD  1 
ATOM 5838 N N   . GLU D 3 133 ? 175.220 156.242 222.903 1.00 117.36 ? 133 GLU B N   1 
ATOM 5839 C CA  . GLU D 3 133 ? 175.349 156.771 224.257 1.00 117.36 ? 133 GLU B CA  1 
ATOM 5840 C C   . GLU D 3 133 ? 176.787 157.143 224.603 1.00 117.36 ? 133 GLU B C   1 
ATOM 5841 O O   . GLU D 3 133 ? 177.036 158.218 225.159 1.00 117.36 ? 133 GLU B O   1 
ATOM 5842 C CB  . GLU D 3 133 ? 174.813 155.758 225.270 1.00 117.36 ? 133 GLU B CB  1 
ATOM 5843 C CG  . GLU D 3 133 ? 175.100 156.118 226.717 1.00 117.36 ? 133 GLU B CG  1 
ATOM 5844 C CD  . GLU D 3 133 ? 174.465 157.433 227.124 1.00 117.36 ? 133 GLU B CD  1 
ATOM 5845 O OE1 . GLU D 3 133 ? 173.323 157.701 226.696 1.00 117.36 ? 133 GLU B OE1 1 
ATOM 5846 O OE2 . GLU D 3 133 ? 175.109 158.198 227.872 1.00 117.36 ? 133 GLU B OE2 1 
ATOM 5847 N N   . GLU D 3 134 ? 177.736 156.266 224.277 1.00 120.56 ? 134 GLU B N   1 
ATOM 5848 C CA  . GLU D 3 134 ? 179.131 156.452 224.664 1.00 120.56 ? 134 GLU B CA  1 
ATOM 5849 C C   . GLU D 3 134 ? 179.741 157.692 224.019 1.00 120.56 ? 134 GLU B C   1 
ATOM 5850 O O   . GLU D 3 134 ? 180.714 158.252 224.536 1.00 120.56 ? 134 GLU B O   1 
ATOM 5851 C CB  . GLU D 3 134 ? 179.944 155.205 224.304 1.00 120.56 ? 134 GLU B CB  1 
ATOM 5852 C CG  . GLU D 3 134 ? 181.417 155.266 224.667 1.00 120.56 ? 134 GLU B CG  1 
ATOM 5853 C CD  . GLU D 3 134 ? 182.301 155.480 223.456 1.00 120.56 ? 134 GLU B CD  1 
ATOM 5854 O OE1 . GLU D 3 134 ? 183.178 156.367 223.510 1.00 120.56 ? 134 GLU B OE1 1 
ATOM 5855 O OE2 . GLU D 3 134 ? 182.119 154.762 222.451 1.00 120.56 ? 134 GLU B OE2 1 
ATOM 5856 N N   . ILE D 3 135 ? 179.170 158.137 222.901 1.00 117.49 ? 135 ILE B N   1 
ATOM 5857 C CA  . ILE D 3 135 ? 179.711 159.262 222.143 1.00 117.49 ? 135 ILE B CA  1 
ATOM 5858 C C   . ILE D 3 135 ? 179.715 160.530 222.988 1.00 117.49 ? 135 ILE B C   1 
ATOM 5859 O O   . ILE D 3 135 ? 180.536 161.429 222.770 1.00 117.49 ? 135 ILE B O   1 
ATOM 5860 C CB  . ILE D 3 135 ? 178.934 159.470 220.828 1.00 117.49 ? 135 ILE B CB  1 
ATOM 5861 C CG1 . ILE D 3 135 ? 179.899 159.833 219.702 1.00 117.49 ? 135 ILE B CG1 1 
ATOM 5862 C CG2 . ILE D 3 135 ? 177.870 160.550 220.972 1.00 117.49 ? 135 ILE B CG2 1 
ATOM 5863 C CD1 . ILE D 3 135 ? 180.672 158.664 219.156 1.00 117.49 ? 135 ILE B CD1 1 
ATOM 5864 N N   . ARG D 3 136 ? 178.805 160.614 223.957 1.00 114.19 ? 136 ARG B N   1 
ATOM 5865 C CA  . ARG D 3 136 ? 178.696 161.803 224.793 1.00 114.19 ? 136 ARG B CA  1 
ATOM 5866 C C   . ARG D 3 136 ? 179.938 162.000 225.651 1.00 114.19 ? 136 ARG B C   1 
ATOM 5867 O O   . ARG D 3 136 ? 180.399 163.130 225.831 1.00 114.19 ? 136 ARG B O   1 
ATOM 5868 C CB  . ARG D 3 136 ? 177.444 161.725 225.664 1.00 114.19 ? 136 ARG B CB  1 
ATOM 5869 C CG  . ARG D 3 136 ? 176.201 162.202 224.946 1.00 114.19 ? 136 ARG B CG  1 
ATOM 5870 C CD  . ARG D 3 136 ? 175.008 161.323 225.241 1.00 114.19 ? 136 ARG B CD  1 
ATOM 5871 N NE  . ARG D 3 136 ? 173.763 162.058 225.066 1.00 114.19 ? 136 ARG B NE  1 
ATOM 5872 C CZ  . ARG D 3 136 ? 172.561 161.501 225.039 1.00 114.19 ? 136 ARG B CZ  1 
ATOM 5873 N NH1 . ARG D 3 136 ? 172.402 160.195 225.171 1.00 114.19 ? 136 ARG B NH1 1 
ATOM 5874 N NH2 . ARG D 3 136 ? 171.493 162.274 224.872 1.00 114.19 ? 136 ARG B NH2 1 
ATOM 5875 N N   . LYS D 3 137 ? 180.494 160.913 226.174 1.00 118.39 ? 137 LYS B N   1 
ATOM 5876 C CA  . LYS D 3 137 ? 181.680 161.011 227.027 1.00 118.39 ? 137 LYS B CA  1 
ATOM 5877 C C   . LYS D 3 137 ? 182.910 161.538 226.288 1.00 118.39 ? 137 LYS B C   1 
ATOM 5878 O O   . LYS D 3 137 ? 183.955 161.718 226.928 1.00 118.39 ? 137 LYS B O   1 
ATOM 5879 C CB  . LYS D 3 137 ? 182.001 159.653 227.660 1.00 118.39 ? 137 LYS B CB  1 
ATOM 5880 C CG  . LYS D 3 137 ? 181.123 159.256 228.852 1.00 118.39 ? 137 LYS B CG  1 
ATOM 5881 C CD  . LYS D 3 137 ? 179.658 159.071 228.481 1.00 118.39 ? 137 LYS B CD  1 
ATOM 5882 C CE  . LYS D 3 137 ? 178.916 158.260 229.527 1.00 118.39 ? 137 LYS B CE  1 
ATOM 5883 N NZ  . LYS D 3 137 ? 177.440 158.391 229.376 1.00 118.39 ? 137 LYS B NZ  1 
ATOM 5884 N N   . THR D 3 138 ? 182.828 161.790 224.981 1.00 113.64 ? 138 THR B N   1 
ATOM 5885 C CA  . THR D 3 138 ? 183.934 162.360 224.223 1.00 113.64 ? 138 THR B CA  1 
ATOM 5886 C C   . THR D 3 138 ? 183.583 163.706 223.601 1.00 113.64 ? 138 THR B C   1 
ATOM 5887 O O   . THR D 3 138 ? 184.465 164.365 223.039 1.00 113.64 ? 138 THR B O   1 
ATOM 5888 C CB  . THR D 3 138 ? 184.391 161.388 223.131 1.00 113.64 ? 138 THR B CB  1 
ATOM 5889 O OG1 . THR D 3 138 ? 183.251 160.728 222.568 1.00 113.64 ? 138 THR B OG1 1 
ATOM 5890 C CG2 . THR D 3 138 ? 185.339 160.349 223.707 1.00 113.64 ? 138 THR B CG2 1 
ATOM 5891 N N   . PHE D 3 139 ? 182.323 164.133 223.685 1.00 107.76 ? 139 PHE B N   1 
ATOM 5892 C CA  . PHE D 3 139 ? 181.924 165.413 223.114 1.00 107.76 ? 139 PHE B CA  1 
ATOM 5893 C C   . PHE D 3 139 ? 181.069 166.207 224.095 1.00 107.76 ? 139 PHE B C   1 
ATOM 5894 O O   . PHE D 3 139 ? 180.840 167.404 223.896 1.00 107.76 ? 139 PHE B O   1 
ATOM 5895 C CB  . PHE D 3 139 ? 181.165 165.202 221.803 1.00 107.76 ? 139 PHE B CB  1 
ATOM 5896 C CG  . PHE D 3 139 ? 182.032 164.749 220.665 1.00 107.76 ? 139 PHE B CG  1 
ATOM 5897 C CD1 . PHE D 3 139 ? 183.019 165.574 220.156 1.00 107.76 ? 139 PHE B CD1 1 
ATOM 5898 C CD2 . PHE D 3 139 ? 181.854 163.499 220.100 1.00 107.76 ? 139 PHE B CD2 1 
ATOM 5899 C CE1 . PHE D 3 139 ? 183.814 165.157 219.108 1.00 107.76 ? 139 PHE B CE1 1 
ATOM 5900 C CE2 . PHE D 3 139 ? 182.645 163.078 219.052 1.00 107.76 ? 139 PHE B CE2 1 
ATOM 5901 C CZ  . PHE D 3 139 ? 183.626 163.908 218.556 1.00 107.76 ? 139 PHE B CZ  1 
ATOM 5902 N N   . ASN D 3 140 ? 180.600 165.545 225.154 1.00 104.65 ? 140 ASN B N   1 
ATOM 5903 C CA  . ASN D 3 140 ? 179.777 166.169 226.194 1.00 104.65 ? 140 ASN B CA  1 
ATOM 5904 C C   . ASN D 3 140 ? 178.539 166.844 225.608 1.00 104.65 ? 140 ASN B C   1 
ATOM 5905 O O   . ASN D 3 140 ? 178.396 168.067 225.668 1.00 104.65 ? 140 ASN B O   1 
ATOM 5906 C CB  . ASN D 3 140 ? 180.595 167.162 227.025 1.00 104.65 ? 140 ASN B CB  1 
ATOM 5907 C CG  . ASN D 3 140 ? 179.914 167.539 228.332 1.00 104.65 ? 140 ASN B CG  1 
ATOM 5908 O OD1 . ASN D 3 140 ? 178.758 167.962 228.352 1.00 104.65 ? 140 ASN B OD1 1 
ATOM 5909 N ND2 . ASN D 3 140 ? 180.635 167.383 229.435 1.00 104.65 ? 140 ASN B ND2 1 
ATOM 5910 N N   . ILE D 3 141 ? 177.646 166.054 225.014 1.00 107.34 ? 141 ILE B N   1 
ATOM 5911 C CA  . ILE D 3 141 ? 176.381 166.566 224.499 1.00 107.34 ? 141 ILE B CA  1 
ATOM 5912 C C   . ILE D 3 141 ? 175.338 166.444 225.604 1.00 107.34 ? 141 ILE B C   1 
ATOM 5913 O O   . ILE D 3 141 ? 175.485 165.626 226.519 1.00 107.34 ? 141 ILE B O   1 
ATOM 5914 C CB  . ILE D 3 141 ? 175.949 165.810 223.227 1.00 107.34 ? 141 ILE B CB  1 
ATOM 5915 C CG1 . ILE D 3 141 ? 177.112 165.714 222.242 1.00 107.34 ? 141 ILE B CG1 1 
ATOM 5916 C CG2 . ILE D 3 141 ? 174.782 166.505 222.546 1.00 107.34 ? 141 ILE B CG2 1 
ATOM 5917 C CD1 . ILE D 3 141 ? 177.727 164.336 222.166 1.00 107.34 ? 141 ILE B CD1 1 
ATOM 5918 N N   . LYS D 3 142 ? 174.279 167.251 225.531 1.00 111.51 ? 142 LYS B N   1 
ATOM 5919 C CA  . LYS D 3 142 ? 173.209 167.193 226.519 1.00 111.51 ? 142 LYS B CA  1 
ATOM 5920 C C   . LYS D 3 142 ? 172.426 165.894 226.363 1.00 111.51 ? 142 LYS B C   1 
ATOM 5921 O O   . LYS D 3 142 ? 172.688 165.115 225.441 1.00 111.51 ? 142 LYS B O   1 
ATOM 5922 C CB  . LYS D 3 142 ? 172.289 168.409 226.380 1.00 111.51 ? 142 LYS B CB  1 
ATOM 5923 C CG  . LYS D 3 142 ? 171.574 168.810 227.662 1.00 111.51 ? 142 LYS B CG  1 
ATOM 5924 C CD  . LYS D 3 142 ? 172.477 169.647 228.555 1.00 111.51 ? 142 LYS B CD  1 
ATOM 5925 C CE  . LYS D 3 142 ? 172.318 171.132 228.270 1.00 111.51 ? 142 LYS B CE  1 
ATOM 5926 N NZ  . LYS D 3 142 ? 173.250 171.958 229.088 1.00 111.51 ? 142 LYS B NZ  1 
ATOM 5927 N N   . ASN D 3 143 ? 171.458 165.651 227.245 1.00 121.77 ? 143 ASN B N   1 
ATOM 5928 C CA  . ASN D 3 143 ? 170.764 164.369 227.254 1.00 121.77 ? 143 ASN B CA  1 
ATOM 5929 C C   . ASN D 3 143 ? 169.266 164.524 227.479 1.00 121.77 ? 143 ASN B C   1 
ATOM 5930 O O   . ASN D 3 143 ? 168.809 164.609 228.623 1.00 121.77 ? 143 ASN B O   1 
ATOM 5931 C CB  . ASN D 3 143 ? 171.362 163.456 228.329 1.00 121.77 ? 143 ASN B CB  1 
ATOM 5932 C CG  . ASN D 3 143 ? 170.709 162.087 228.364 1.00 121.77 ? 143 ASN B CG  1 
ATOM 5933 O OD1 . ASN D 3 143 ? 171.141 161.163 227.675 1.00 121.77 ? 143 ASN B OD1 1 
ATOM 5934 N ND2 . ASN D 3 143 ? 169.668 161.947 229.177 1.00 121.77 ? 143 ASN B ND2 1 
ATOM 5935 N N   . ASP D 3 144 ? 168.587 164.645 226.344 1.00 118.37 ? 144 ASP B N   1 
ATOM 5936 C CA  . ASP D 3 144 ? 167.236 165.088 226.503 1.00 118.37 ? 144 ASP B CA  1 
ATOM 5937 C C   . ASP D 3 144 ? 166.020 164.672 225.807 1.00 118.37 ? 144 ASP B C   1 
ATOM 5938 O O   . ASP D 3 144 ? 165.992 163.666 225.133 1.00 118.37 ? 144 ASP B O   1 
ATOM 5939 C CB  . ASP D 3 144 ? 167.310 166.532 226.029 1.00 118.37 ? 144 ASP B CB  1 
ATOM 5940 C CG  . ASP D 3 144 ? 168.407 166.745 225.034 1.00 118.37 ? 144 ASP B CG  1 
ATOM 5941 O OD1 . ASP D 3 144 ? 169.405 165.998 225.103 1.00 118.37 ? 144 ASP B OD1 1 
ATOM 5942 O OD2 . ASP D 3 144 ? 168.276 167.650 224.189 1.00 118.37 ? 144 ASP B OD2 1 
ATOM 5943 N N   . PHE D 3 145 ? 165.011 165.512 226.008 1.00 127.70 ? 145 PHE B N   1 
ATOM 5944 C CA  . PHE D 3 145 ? 163.696 165.301 225.427 1.00 127.70 ? 145 PHE B CA  1 
ATOM 5945 C C   . PHE D 3 145 ? 162.976 164.045 225.872 1.00 127.70 ? 145 PHE B C   1 
ATOM 5946 O O   . PHE D 3 145 ? 163.545 162.959 225.847 1.00 127.70 ? 145 PHE B O   1 
ATOM 5947 C CB  . PHE D 3 145 ? 163.749 165.408 223.929 1.00 127.70 ? 145 PHE B CB  1 
ATOM 5948 C CG  . PHE D 3 145 ? 163.945 166.804 223.413 1.00 127.70 ? 145 PHE B CG  1 
ATOM 5949 C CD1 . PHE D 3 145 ? 162.970 167.406 222.634 1.00 127.70 ? 145 PHE B CD1 1 
ATOM 5950 C CD2 . PHE D 3 145 ? 165.115 167.497 223.667 1.00 127.70 ? 145 PHE B CD2 1 
ATOM 5951 C CE1 . PHE D 3 145 ? 163.149 168.681 222.138 1.00 127.70 ? 145 PHE B CE1 1 
ATOM 5952 C CE2 . PHE D 3 145 ? 165.300 168.773 223.176 1.00 127.70 ? 145 PHE B CE2 1 
ATOM 5953 C CZ  . PHE D 3 145 ? 164.315 169.364 222.410 1.00 127.70 ? 145 PHE B CZ  1 
ATOM 5954 N N   . THR D 3 146 ? 161.718 164.214 226.270 1.00 149.02 ? 146 THR B N   1 
ATOM 5955 C CA  . THR D 3 146 ? 160.929 163.102 226.778 1.00 149.02 ? 146 THR B CA  1 
ATOM 5956 C C   . THR D 3 146 ? 161.536 161.778 226.503 1.00 149.02 ? 146 THR B C   1 
ATOM 5957 O O   . THR D 3 146 ? 161.510 161.320 225.365 1.00 149.02 ? 146 THR B O   1 
ATOM 5958 C CB  . THR D 3 146 ? 159.548 163.065 226.127 1.00 149.02 ? 146 THR B CB  1 
ATOM 5959 O OG1 . THR D 3 146 ? 159.120 164.402 225.845 1.00 149.02 ? 146 THR B OG1 1 
ATOM 5960 C CG2 . THR D 3 146 ? 158.554 162.395 227.049 1.00 149.02 ? 146 THR B CG2 1 
ATOM 5961 N N   . GLU D 3 147 ? 162.076 161.142 227.531 1.00 154.92 ? 147 GLU B N   1 
ATOM 5962 C CA  . GLU D 3 147 ? 162.580 159.812 227.342 1.00 154.92 ? 147 GLU B CA  1 
ATOM 5963 C C   . GLU D 3 147 ? 161.651 159.153 226.375 1.00 154.92 ? 147 GLU B C   1 
ATOM 5964 O O   . GLU D 3 147 ? 162.079 158.534 225.413 1.00 154.92 ? 147 GLU B O   1 
ATOM 5965 C CB  . GLU D 3 147 ? 162.533 159.043 228.633 1.00 154.92 ? 147 GLU B CB  1 
ATOM 5966 C CG  . GLU D 3 147 ? 163.349 157.766 228.605 1.00 154.92 ? 147 GLU B CG  1 
ATOM 5967 C CD  . GLU D 3 147 ? 162.735 156.714 227.712 1.00 154.92 ? 147 GLU B CD  1 
ATOM 5968 O OE1 . GLU D 3 147 ? 161.508 156.513 227.805 1.00 154.92 ? 147 GLU B OE1 1 
ATOM 5969 O OE2 . GLU D 3 147 ? 163.470 156.109 226.907 1.00 154.92 ? 147 GLU B OE2 1 
ATOM 5970 N N   . GLU D 3 148 ? 160.358 159.300 226.618 1.00 150.27 ? 148 GLU B N   1 
ATOM 5971 C CA  . GLU D 3 148 ? 159.388 158.668 225.754 1.00 150.27 ? 148 GLU B CA  1 
ATOM 5972 C C   . GLU D 3 148 ? 159.672 158.858 224.291 1.00 150.27 ? 148 GLU B C   1 
ATOM 5973 O O   . GLU D 3 148 ? 159.704 157.891 223.570 1.00 150.27 ? 148 GLU B O   1 
ATOM 5974 C CB  . GLU D 3 148 ? 157.992 159.176 226.027 1.00 150.27 ? 148 GLU B CB  1 
ATOM 5975 C CG  . GLU D 3 148 ? 156.987 158.044 225.997 1.00 150.27 ? 148 GLU B CG  1 
ATOM 5976 C CD  . GLU D 3 148 ? 157.668 156.694 225.870 1.00 150.27 ? 148 GLU B CD  1 
ATOM 5977 O OE1 . GLU D 3 148 ? 157.802 156.196 224.734 1.00 150.27 ? 148 GLU B OE1 1 
ATOM 5978 O OE2 . GLU D 3 148 ? 158.078 156.133 226.907 1.00 150.27 ? 148 GLU B OE2 1 
ATOM 5979 N N   . GLU D 3 149 ? 159.831 160.086 223.826 1.00 135.41 ? 149 GLU B N   1 
ATOM 5980 C CA  . GLU D 3 149 ? 160.013 160.234 222.403 1.00 135.41 ? 149 GLU B CA  1 
ATOM 5981 C C   . GLU D 3 149 ? 161.118 159.322 222.061 1.00 135.41 ? 149 GLU B C   1 
ATOM 5982 O O   . GLU D 3 149 ? 160.939 158.381 221.327 1.00 135.41 ? 149 GLU B O   1 
ATOM 5983 C CB  . GLU D 3 149 ? 160.409 161.623 221.980 1.00 135.41 ? 149 GLU B CB  1 
ATOM 5984 C CG  . GLU D 3 149 ? 159.928 162.730 222.873 1.00 135.41 ? 149 GLU B CG  1 
ATOM 5985 C CD  . GLU D 3 149 ? 161.077 163.606 223.283 1.00 135.41 ? 149 GLU B CD  1 
ATOM 5986 O OE1 . GLU D 3 149 ? 160.839 164.764 223.682 1.00 135.41 ? 149 GLU B OE1 1 
ATOM 5987 O OE2 . GLU D 3 149 ? 162.220 163.113 223.199 1.00 135.41 ? 149 GLU B OE2 1 
ATOM 5988 N N   . GLU D 3 150 ? 162.276 159.577 222.618 1.00 124.52 ? 150 GLU B N   1 
ATOM 5989 C CA  . GLU D 3 150 ? 163.363 158.682 222.372 1.00 124.52 ? 150 GLU B CA  1 
ATOM 5990 C C   . GLU D 3 150 ? 162.795 157.331 222.360 1.00 124.52 ? 150 GLU B C   1 
ATOM 5991 O O   . GLU D 3 150 ? 162.833 156.636 221.377 1.00 124.52 ? 150 GLU B O   1 
ATOM 5992 C CB  . GLU D 3 150 ? 164.375 158.765 223.493 1.00 124.52 ? 150 GLU B CB  1 
ATOM 5993 C CG  . GLU D 3 150 ? 165.646 157.970 223.239 1.00 124.52 ? 150 GLU B CG  1 
ATOM 5994 C CD  . GLU D 3 150 ? 165.460 156.476 223.420 1.00 124.52 ? 150 GLU B CD  1 
ATOM 5995 O OE1 . GLU D 3 150 ? 164.690 156.077 224.316 1.00 124.52 ? 150 GLU B OE1 1 
ATOM 5996 O OE2 . GLU D 3 150 ? 166.078 155.701 222.662 1.00 124.52 ? 150 GLU B OE2 1 
ATOM 5997 N N   . ALA D 3 151 ? 162.257 156.957 223.478 1.00 119.97 ? 151 ALA B N   1 
ATOM 5998 C CA  . ALA D 3 151 ? 161.784 155.645 223.578 1.00 119.97 ? 151 ALA B CA  1 
ATOM 5999 C C   . ALA D 3 151 ? 160.849 155.298 222.429 1.00 119.97 ? 151 ALA B C   1 
ATOM 6000 O O   . ALA D 3 151 ? 160.784 154.138 222.052 1.00 119.97 ? 151 ALA B O   1 
ATOM 6001 C CB  . ALA D 3 151 ? 161.097 155.501 224.886 1.00 119.97 ? 151 ALA B CB  1 
ATOM 6002 N N   . GLN D 3 152 ? 160.144 156.251 221.835 1.00 120.45 ? 152 GLN B N   1 
ATOM 6003 C CA  . GLN D 3 152 ? 159.314 155.923 220.666 1.00 120.45 ? 152 GLN B CA  1 
ATOM 6004 C C   . GLN D 3 152 ? 159.825 156.619 219.458 1.00 120.45 ? 152 GLN B C   1 
ATOM 6005 O O   . GLN D 3 152 ? 159.093 156.822 218.493 1.00 120.45 ? 152 GLN B O   1 
ATOM 6006 C CB  . GLN D 3 152 ? 157.886 156.312 220.871 1.00 120.45 ? 152 GLN B CB  1 
ATOM 6007 C CG  . GLN D 3 152 ? 157.690 157.795 221.141 1.00 120.45 ? 152 GLN B CG  1 
ATOM 6008 C CD  . GLN D 3 152 ? 156.825 158.057 222.357 1.00 120.45 ? 152 GLN B CD  1 
ATOM 6009 O OE1 . GLN D 3 152 ? 156.053 157.199 222.776 1.00 120.45 ? 152 GLN B OE1 1 
ATOM 6010 N NE2 . GLN D 3 152 ? 156.945 159.250 222.925 1.00 120.45 ? 152 GLN B NE2 1 
ATOM 6011 N N   . VAL D 3 153 ? 161.106 156.958 219.502 1.00 114.74 ? 153 VAL B N   1 
ATOM 6012 C CA  . VAL D 3 153 ? 161.749 157.590 218.371 1.00 114.74 ? 153 VAL B CA  1 
ATOM 6013 C C   . VAL D 3 153 ? 162.865 156.722 217.968 1.00 114.74 ? 153 VAL B C   1 
ATOM 6014 O O   . VAL D 3 153 ? 162.872 156.182 216.879 1.00 114.74 ? 153 VAL B O   1 
ATOM 6015 C CB  . VAL D 3 153 ? 162.418 158.912 218.726 1.00 114.74 ? 153 VAL B CB  1 
ATOM 6016 C CG1 . VAL D 3 153 ? 163.452 159.291 217.675 1.00 114.74 ? 153 VAL B CG1 1 
ATOM 6017 C CG2 . VAL D 3 153 ? 161.377 160.012 218.820 1.00 114.74 ? 153 VAL B CG2 1 
ATOM 6018 N N   . GLY D 3 154 ? 163.829 156.586 218.852 1.00 121.07 ? 154 GLY B N   1 
ATOM 6019 C CA  . GLY D 3 154 ? 164.963 155.760 218.562 1.00 121.07 ? 154 GLY B CA  1 
ATOM 6020 C C   . GLY D 3 154 ? 164.415 154.390 218.684 1.00 121.07 ? 154 GLY B C   1 
ATOM 6021 O O   . GLY D 3 154 ? 164.878 153.599 219.481 1.00 121.07 ? 154 GLY B O   1 
ATOM 6022 N N   . SER D 3 155 ? 163.408 154.099 217.900 1.00 121.23 ? 155 SER B N   1 
ATOM 6023 C CA  . SER D 3 155 ? 162.758 152.828 217.990 1.00 121.23 ? 155 SER B CA  1 
ATOM 6024 C C   . SER D 3 155 ? 162.183 152.577 216.646 1.00 121.23 ? 155 SER B C   1 
ATOM 6025 O O   . SER D 3 155 ? 161.250 151.803 216.497 1.00 121.23 ? 155 SER B O   1 
ATOM 6026 C CB  . SER D 3 155 ? 161.646 152.927 218.988 1.00 30.00  ? 155 SER B CB  1 
ATOM 6027 O OG  . SER D 3 155 ? 161.588 154.231 219.538 1.00 30.00  ? 155 SER B OG  1 
ATOM 6028 N N   . THR D 3 156 ? 162.728 153.252 215.653 1.00 120.70 ? 156 THR B N   1 
ATOM 6029 C CA  . THR D 3 156 ? 162.262 153.077 214.309 1.00 120.70 ? 156 THR B CA  1 
ATOM 6030 C C   . THR D 3 156 ? 163.438 152.729 213.410 1.00 120.70 ? 156 THR B C   1 
ATOM 6031 O O   . THR D 3 156 ? 163.531 153.227 212.300 1.00 120.70 ? 156 THR B O   1 
ATOM 6032 C CB  . THR D 3 156 ? 161.578 154.361 213.832 1.00 30.00  ? 156 THR B CB  1 
ATOM 6033 O OG1 . THR D 3 156 ? 162.567 155.307 213.416 1.00 30.00  ? 156 THR B OG1 1 
ATOM 6034 C CG2 . THR D 3 156 ? 160.765 154.974 214.950 1.00 30.00  ? 156 THR B CG2 1 
ATOM 6035 N N   . GLN D 3 157 ? 164.335 151.861 213.868 1.00 122.42 ? 157 GLN B N   1 
ATOM 6036 C CA  . GLN D 3 157 ? 165.516 151.608 213.059 1.00 122.42 ? 157 GLN B CA  1 
ATOM 6037 C C   . GLN D 3 157 ? 166.363 150.334 213.275 1.00 122.42 ? 157 GLN B C   1 
ATOM 6038 O O   . GLN D 3 157 ? 165.795 149.276 213.440 1.00 122.42 ? 157 GLN B O   1 
ATOM 6039 C CB  . GLN D 3 157 ? 166.417 152.828 213.204 1.00 30.00  ? 157 GLN B CB  1 
ATOM 6040 C CG  . GLN D 3 157 ? 166.227 153.615 214.484 1.00 30.00  ? 157 GLN B CG  1 
ATOM 6041 C CD  . GLN D 3 157 ? 165.346 154.822 214.269 1.00 30.00  ? 157 GLN B CD  1 
ATOM 6042 O OE1 . GLN D 3 157 ? 165.171 155.274 213.142 1.00 30.00  ? 157 GLN B OE1 1 
ATOM 6043 N NE2 . GLN D 3 157 ? 164.759 155.329 215.339 1.00 30.00  ? 157 GLN B NE2 1 
ATOM 6044 N N   . PHE D 3 158 ? 167.627 150.533 213.565 1.00 126.03 ? 158 PHE B N   1 
ATOM 6045 C CA  . PHE D 3 158 ? 168.495 149.404 213.708 1.00 126.03 ? 158 PHE B CA  1 
ATOM 6046 C C   . PHE D 3 158 ? 168.130 148.789 212.439 1.00 126.03 ? 158 PHE B C   1 
ATOM 6047 O O   . PHE D 3 158 ? 168.306 149.378 211.378 1.00 126.03 ? 158 PHE B O   1 
ATOM 6048 C CB  . PHE D 3 158 ? 168.123 148.486 214.863 1.00 30.00  ? 158 PHE B CB  1 
ATOM 6049 C CG  . PHE D 3 158 ? 168.923 147.217 214.903 1.00 30.00  ? 158 PHE B CG  1 
ATOM 6050 C CD1 . PHE D 3 158 ? 168.335 146.030 215.289 1.00 30.00  ? 158 PHE B CD1 1 
ATOM 6051 C CD2 . PHE D 3 158 ? 170.249 147.211 214.516 1.00 30.00  ? 158 PHE B CD2 1 
ATOM 6052 C CE1 . PHE D 3 158 ? 169.063 144.861 215.314 1.00 30.00  ? 158 PHE B CE1 1 
ATOM 6053 C CE2 . PHE D 3 158 ? 170.985 146.048 214.536 1.00 30.00  ? 158 PHE B CE2 1 
ATOM 6054 C CZ  . PHE D 3 158 ? 170.391 144.869 214.937 1.00 30.00  ? 158 PHE B CZ  1 
ATOM 6055 N N   . CYS D 3 159 ? 167.577 147.613 212.550 1.00 123.53 ? 159 CYS B N   1 
ATOM 6056 C CA  . CYS D 3 159 ? 167.206 146.984 211.385 1.00 123.53 ? 159 CYS B CA  1 
ATOM 6057 C C   . CYS D 3 159 ? 168.385 147.226 210.494 1.00 123.53 ? 159 CYS B C   1 
ATOM 6058 O O   . CYS D 3 159 ? 169.532 147.139 210.929 1.00 123.53 ? 159 CYS B O   1 
ATOM 6059 C CB  . CYS D 3 159 ? 165.969 147.689 210.882 1.00 30.00  ? 159 CYS B CB  1 
ATOM 6060 S SG  . CYS D 3 159 ? 164.486 147.321 211.842 1.00 30.00  ? 159 CYS B SG  1 
ATOM 6061 N N   . LEU D 3 160 ? 168.127 147.572 209.253 1.00 110.60 ? 160 LEU B N   1 
ATOM 6062 C CA  . LEU D 3 160 ? 169.216 147.698 208.368 1.00 110.60 ? 160 LEU B CA  1 
ATOM 6063 C C   . LEU D 3 160 ? 168.944 148.435 207.110 1.00 110.60 ? 160 LEU B C   1 
ATOM 6064 O O   . LEU D 3 160 ? 169.695 148.304 206.162 1.00 110.60 ? 160 LEU B O   1 
ATOM 6065 C CB  . LEU D 3 160 ? 169.610 146.317 207.950 1.00 30.00  ? 160 LEU B CB  1 
ATOM 6066 C CG  . LEU D 3 160 ? 170.519 145.493 208.887 1.00 30.00  ? 160 LEU B CG  1 
ATOM 6067 C CD1 . LEU D 3 160 ? 169.767 144.469 209.734 1.00 30.00  ? 160 LEU B CD1 1 
ATOM 6068 C CD2 . LEU D 3 160 ? 171.733 144.860 208.229 1.00 30.00  ? 160 LEU B CD2 1 
ATOM 6069 N N   . LYS E 4 1   ? 175.302 181.952 222.984 1.00 128.83 ? 13  LYS A N   1 
ATOM 6070 C CA  . LYS E 4 1   ? 174.731 183.208 222.510 1.00 128.83 ? 13  LYS A CA  1 
ATOM 6071 C C   . LYS E 4 1   ? 175.814 184.070 221.870 1.00 128.83 ? 13  LYS A C   1 
ATOM 6072 O O   . LYS E 4 1   ? 176.279 183.775 220.770 1.00 128.83 ? 13  LYS A O   1 
ATOM 6073 C CB  . LYS E 4 1   ? 174.058 183.972 223.656 1.00 128.83 ? 13  LYS A CB  1 
ATOM 6074 C CG  . LYS E 4 1   ? 173.150 183.139 224.560 1.00 128.83 ? 13  LYS A CG  1 
ATOM 6075 C CD  . LYS E 4 1   ? 172.289 182.155 223.780 1.00 128.83 ? 13  LYS A CD  1 
ATOM 6076 C CE  . LYS E 4 1   ? 171.411 181.334 224.711 1.00 128.83 ? 13  LYS A CE  1 
ATOM 6077 N NZ  . LYS E 4 1   ? 170.621 180.309 223.973 1.00 128.83 ? 13  LYS A NZ  1 
ATOM 6078 N N   . GLN E 4 2   ? 176.198 185.139 222.571 1.00 125.81 ? 14  GLN A N   1 
ATOM 6079 C CA  . GLN E 4 2   ? 177.269 186.062 222.198 1.00 125.81 ? 14  GLN A CA  1 
ATOM 6080 C C   . GLN E 4 2   ? 176.916 186.908 220.977 1.00 125.81 ? 14  GLN A C   1 
ATOM 6081 O O   . GLN E 4 2   ? 177.736 187.723 220.537 1.00 125.81 ? 14  GLN A O   1 
ATOM 6082 C CB  . GLN E 4 2   ? 178.592 185.309 221.973 1.00 125.81 ? 14  GLN A CB  1 
ATOM 6083 C CG  . GLN E 4 2   ? 179.864 186.158 221.984 1.00 125.81 ? 14  GLN A CG  1 
ATOM 6084 C CD  . GLN E 4 2   ? 180.400 186.439 220.591 1.00 125.81 ? 14  GLN A CD  1 
ATOM 6085 O OE1 . GLN E 4 2   ? 179.775 186.089 219.591 1.00 125.81 ? 14  GLN A OE1 1 
ATOM 6086 N NE2 . GLN E 4 2   ? 181.563 187.075 220.522 1.00 125.81 ? 14  GLN A NE2 1 
ATOM 6087 N N   . ILE E 4 3   ? 175.704 186.779 220.439 1.00 111.98 ? 15  ILE A N   1 
ATOM 6088 C CA  . ILE E 4 3   ? 175.351 187.488 219.214 1.00 111.98 ? 15  ILE A CA  1 
ATOM 6089 C C   . ILE E 4 3   ? 174.344 188.596 219.484 1.00 111.98 ? 15  ILE A C   1 
ATOM 6090 O O   . ILE E 4 3   ? 174.621 189.775 219.239 1.00 111.98 ? 15  ILE A O   1 
ATOM 6091 C CB  . ILE E 4 3   ? 174.790 186.530 218.147 1.00 111.98 ? 15  ILE A CB  1 
ATOM 6092 C CG1 . ILE E 4 3   ? 175.598 185.228 218.076 1.00 111.98 ? 15  ILE A CG1 1 
ATOM 6093 C CG2 . ILE E 4 3   ? 174.723 187.234 216.802 1.00 111.98 ? 15  ILE A CG2 1 
ATOM 6094 C CD1 . ILE E 4 3   ? 177.088 185.415 217.896 1.00 111.98 ? 15  ILE A CD1 1 
ATOM 6095 N N   . GLY E 4 4   ? 173.169 188.227 219.984 1.00 111.79 ? 16  GLY A N   1 
ATOM 6096 C CA  . GLY E 4 4   ? 172.054 189.149 220.025 1.00 111.79 ? 16  GLY A CA  1 
ATOM 6097 C C   . GLY E 4 4   ? 171.294 189.156 218.715 1.00 111.79 ? 16  GLY A C   1 
ATOM 6098 O O   . GLY E 4 4   ? 171.631 188.463 217.750 1.00 111.79 ? 16  GLY A O   1 
ATOM 6099 N N   . LEU E 4 5   ? 170.231 189.957 218.680 1.00 106.81 ? 17  LEU A N   1 
ATOM 6100 C CA  . LEU E 4 5   ? 169.402 190.033 217.487 1.00 106.81 ? 17  LEU A CA  1 
ATOM 6101 C C   . LEU E 4 5   ? 169.002 191.448 217.092 1.00 106.81 ? 17  LEU A C   1 
ATOM 6102 O O   . LEU E 4 5   ? 168.597 191.649 215.943 1.00 106.81 ? 17  LEU A O   1 
ATOM 6103 C CB  . LEU E 4 5   ? 168.138 189.168 217.669 1.00 106.81 ? 17  LEU A CB  1 
ATOM 6104 C CG  . LEU E 4 5   ? 166.894 189.698 218.396 1.00 106.81 ? 17  LEU A CG  1 
ATOM 6105 C CD1 . LEU E 4 5   ? 165.929 190.428 217.461 1.00 106.81 ? 17  LEU A CD1 1 
ATOM 6106 C CD2 . LEU E 4 5   ? 166.183 188.565 219.123 1.00 106.81 ? 17  LEU A CD2 1 
ATOM 6107 N N   . ASP E 4 6   ? 169.107 192.433 217.988 1.00 97.88  ? 18  ASP A N   1 
ATOM 6108 C CA  . ASP E 4 6   ? 168.649 193.783 217.686 1.00 97.88  ? 18  ASP A CA  1 
ATOM 6109 C C   . ASP E 4 6   ? 169.780 194.803 217.663 1.00 97.88  ? 18  ASP A C   1 
ATOM 6110 O O   . ASP E 4 6   ? 169.594 195.900 217.123 1.00 97.88  ? 18  ASP A O   1 
ATOM 6111 C CB  . ASP E 4 6   ? 167.574 194.227 218.683 1.00 97.88  ? 18  ASP A CB  1 
ATOM 6112 C CG  . ASP E 4 6   ? 166.597 195.214 218.078 1.00 97.88  ? 18  ASP A CG  1 
ATOM 6113 O OD1 . ASP E 4 6   ? 166.973 196.390 217.888 1.00 97.88  ? 18  ASP A OD1 1 
ATOM 6114 O OD2 . ASP E 4 6   ? 165.453 194.812 217.780 1.00 97.88  ? 18  ASP A OD2 1 
ATOM 6115 N N   . GLN E 4 7   ? 170.945 194.475 218.218 1.00 88.73  ? 19  GLN A N   1 
ATOM 6116 C CA  . GLN E 4 7   ? 172.121 195.319 218.081 1.00 88.73  ? 19  GLN A CA  1 
ATOM 6117 C C   . GLN E 4 7   ? 172.615 195.355 216.643 1.00 88.73  ? 19  GLN A C   1 
ATOM 6118 O O   . GLN E 4 7   ? 173.226 196.341 216.221 1.00 88.73  ? 19  GLN A O   1 
ATOM 6119 C CB  . GLN E 4 7   ? 173.231 194.832 219.015 1.00 88.73  ? 19  GLN A CB  1 
ATOM 6120 C CG  . GLN E 4 7   ? 174.291 195.872 219.346 1.00 88.73  ? 19  GLN A CG  1 
ATOM 6121 C CD  . GLN E 4 7   ? 175.326 196.034 218.250 1.00 88.73  ? 19  GLN A CD  1 
ATOM 6122 O OE1 . GLN E 4 7   ? 175.672 195.076 217.558 1.00 88.73  ? 19  GLN A OE1 1 
ATOM 6123 N NE2 . GLN E 4 7   ? 175.821 197.253 218.081 1.00 88.73  ? 19  GLN A NE2 1 
ATOM 6124 N N   . ILE E 4 8   ? 172.334 194.309 215.878 1.00 80.74  ? 20  ILE A N   1 
ATOM 6125 C CA  . ILE E 4 8   ? 172.825 194.167 214.517 1.00 80.74  ? 20  ILE A CA  1 
ATOM 6126 C C   . ILE E 4 8   ? 172.125 195.129 213.558 1.00 80.74  ? 20  ILE A C   1 
ATOM 6127 O O   . ILE E 4 8   ? 172.772 195.740 212.707 1.00 80.74  ? 20  ILE A O   1 
ATOM 6128 C CB  . ILE E 4 8   ? 172.720 192.699 214.042 1.00 80.74  ? 20  ILE A CB  1 
ATOM 6129 C CG1 . ILE E 4 8   ? 173.954 192.320 213.229 1.00 80.74  ? 20  ILE A CG1 1 
ATOM 6130 C CG2 . ILE E 4 8   ? 171.447 192.419 213.255 1.00 80.74  ? 20  ILE A CG2 1 
ATOM 6131 C CD1 . ILE E 4 8   ? 173.977 190.879 212.857 1.00 80.74  ? 20  ILE A CD1 1 
ATOM 6132 N N   . TRP E 4 9   ? 170.803 195.294 213.688 1.00 72.94  ? 21  TRP A N   1 
ATOM 6133 C CA  . TRP E 4 9   ? 170.095 196.165 212.757 1.00 72.94  ? 21  TRP A CA  1 
ATOM 6134 C C   . TRP E 4 9   ? 170.158 197.606 213.245 1.00 72.94  ? 21  TRP A C   1 
ATOM 6135 O O   . TRP E 4 9   ? 169.150 198.319 213.257 1.00 72.94  ? 21  TRP A O   1 
ATOM 6136 C CB  . TRP E 4 9   ? 168.640 195.718 212.590 1.00 72.94  ? 21  TRP A CB  1 
ATOM 6137 C CG  . TRP E 4 9   ? 168.008 196.195 211.317 1.00 72.94  ? 21  TRP A CG  1 
ATOM 6138 C CD1 . TRP E 4 9   ? 166.965 197.062 211.193 1.00 72.94  ? 21  TRP A CD1 1 
ATOM 6139 C CD2 . TRP E 4 9   ? 168.368 195.808 209.986 1.00 72.94  ? 21  TRP A CD2 1 
ATOM 6140 N NE1 . TRP E 4 9   ? 166.661 197.251 209.866 1.00 72.94  ? 21  TRP A NE1 1 
ATOM 6141 C CE2 . TRP E 4 9   ? 167.509 196.489 209.105 1.00 72.94  ? 21  TRP A CE2 1 
ATOM 6142 C CE3 . TRP E 4 9   ? 169.338 194.954 209.455 1.00 72.94  ? 21  TRP A CE3 1 
ATOM 6143 C CZ2 . TRP E 4 9   ? 167.590 196.344 207.723 1.00 72.94  ? 21  TRP A CZ2 1 
ATOM 6144 C CZ3 . TRP E 4 9   ? 169.417 194.812 208.084 1.00 72.94  ? 21  TRP A CZ3 1 
ATOM 6145 C CH2 . TRP E 4 9   ? 168.549 195.503 207.233 1.00 72.94  ? 21  TRP A CH2 1 
ATOM 6146 N N   . ASP E 4 10  ? 171.353 198.035 213.637 1.00 79.32  ? 22  ASP A N   1 
ATOM 6147 C CA  . ASP E 4 10  ? 171.636 199.431 213.920 1.00 79.32  ? 22  ASP A CA  1 
ATOM 6148 C C   . ASP E 4 10  ? 172.987 199.842 213.360 1.00 79.32  ? 22  ASP A C   1 
ATOM 6149 O O   . ASP E 4 10  ? 173.240 201.042 213.214 1.00 79.32  ? 22  ASP A O   1 
ATOM 6150 C CB  . ASP E 4 10  ? 171.595 199.697 215.433 1.00 79.32  ? 22  ASP A CB  1 
ATOM 6151 C CG  . ASP E 4 10  ? 170.999 201.046 215.772 1.00 79.32  ? 22  ASP A CG  1 
ATOM 6152 O OD1 . ASP E 4 10  ? 170.862 201.885 214.857 1.00 79.32  ? 22  ASP A OD1 1 
ATOM 6153 O OD2 . ASP E 4 10  ? 170.666 201.268 216.956 1.00 79.32  ? 22  ASP A OD2 1 
ATOM 6154 N N   . ASP E 4 11  ? 173.855 198.883 213.041 1.00 74.28  ? 23  ASP A N   1 
ATOM 6155 C CA  . ASP E 4 11  ? 175.073 199.136 212.282 1.00 74.28  ? 23  ASP A CA  1 
ATOM 6156 C C   . ASP E 4 11  ? 175.100 198.427 210.940 1.00 74.28  ? 23  ASP A C   1 
ATOM 6157 O O   . ASP E 4 11  ? 175.824 198.877 210.046 1.00 74.28  ? 23  ASP A O   1 
ATOM 6158 C CB  . ASP E 4 11  ? 176.311 198.720 213.085 1.00 74.28  ? 23  ASP A CB  1 
ATOM 6159 C CG  . ASP E 4 11  ? 177.607 199.113 212.402 1.00 74.28  ? 23  ASP A CG  1 
ATOM 6160 O OD1 . ASP E 4 11  ? 178.038 200.273 212.565 1.00 74.28  ? 23  ASP A OD1 1 
ATOM 6161 O OD2 . ASP E 4 11  ? 178.190 198.266 211.693 1.00 74.28  ? 23  ASP A OD2 1 
ATOM 6162 N N   . LEU E 4 12  ? 174.346 197.340 210.757 1.00 71.35  ? 24  LEU A N   1 
ATOM 6163 C CA  . LEU E 4 12  ? 174.199 196.768 209.425 1.00 71.35  ? 24  LEU A CA  1 
ATOM 6164 C C   . LEU E 4 12  ? 173.550 197.769 208.482 1.00 71.35  ? 24  LEU A C   1 
ATOM 6165 O O   . LEU E 4 12  ? 174.002 197.940 207.345 1.00 71.35  ? 24  LEU A O   1 
ATOM 6166 C CB  . LEU E 4 12  ? 173.385 195.476 209.484 1.00 71.35  ? 24  LEU A CB  1 
ATOM 6167 C CG  . LEU E 4 12  ? 173.578 194.519 208.307 1.00 71.35  ? 24  LEU A CG  1 
ATOM 6168 C CD1 . LEU E 4 12  ? 175.006 194.030 208.259 1.00 71.35  ? 24  LEU A CD1 1 
ATOM 6169 C CD2 . LEU E 4 12  ? 172.622 193.347 208.394 1.00 71.35  ? 24  LEU A CD2 1 
ATOM 6170 N N   . ARG E 4 13  ? 172.511 198.467 208.945 1.00 71.53  ? 25  ARG A N   1 
ATOM 6171 C CA  . ARG E 4 13  ? 171.920 199.529 208.140 1.00 71.53  ? 25  ARG A CA  1 
ATOM 6172 C C   . ARG E 4 13  ? 172.735 200.804 208.318 1.00 71.53  ? 25  ARG A C   1 
ATOM 6173 O O   . ARG E 4 13  ? 172.191 201.882 208.576 1.00 71.53  ? 25  ARG A O   1 
ATOM 6174 C CB  . ARG E 4 13  ? 170.454 199.749 208.521 1.00 71.53  ? 25  ARG A CB  1 
ATOM 6175 C CG  . ARG E 4 13  ? 169.660 200.561 207.509 1.00 71.53  ? 25  ARG A CG  1 
ATOM 6176 C CD  . ARG E 4 13  ? 168.589 201.396 208.188 1.00 71.53  ? 25  ARG A CD  1 
ATOM 6177 N NE  . ARG E 4 13  ? 167.298 200.718 208.205 1.00 71.53  ? 25  ARG A NE  1 
ATOM 6178 C CZ  . ARG E 4 13  ? 166.234 201.122 207.526 1.00 71.53  ? 25  ARG A CZ  1 
ATOM 6179 N NH1 . ARG E 4 13  ? 166.271 202.199 206.759 1.00 71.53  ? 25  ARG A NH1 1 
ATOM 6180 N NH2 . ARG E 4 13  ? 165.103 200.428 207.618 1.00 71.53  ? 25  ARG A NH2 1 
ATOM 6181 N N   . ALA E 4 14  ? 174.057 200.670 208.191 1.00 75.91  ? 26  ALA A N   1 
ATOM 6182 C CA  . ALA E 4 14  ? 174.938 201.822 208.044 1.00 75.91  ? 26  ALA A CA  1 
ATOM 6183 C C   . ALA E 4 14  ? 175.976 201.550 206.963 1.00 75.91  ? 26  ALA A C   1 
ATOM 6184 O O   . ALA E 4 14  ? 176.701 202.470 206.568 1.00 75.91  ? 26  ALA A O   1 
ATOM 6185 C CB  . ALA E 4 14  ? 175.628 202.165 209.370 1.00 75.91  ? 26  ALA A CB  1 
ATOM 6186 N N   . GLY E 4 15  ? 176.065 200.312 206.486 1.00 73.59  ? 27  GLY A N   1 
ATOM 6187 C CA  . GLY E 4 15  ? 176.891 199.964 205.352 1.00 73.59  ? 27  GLY A CA  1 
ATOM 6188 C C   . GLY E 4 15  ? 176.071 199.275 204.284 1.00 73.59  ? 27  GLY A C   1 
ATOM 6189 O O   . GLY E 4 15  ? 176.440 199.280 203.107 1.00 73.59  ? 27  GLY A O   1 
ATOM 6190 N N   . ILE E 4 16  ? 174.941 198.691 204.683 1.00 68.87  ? 28  ILE A N   1 
ATOM 6191 C CA  . ILE E 4 16  ? 174.024 198.065 203.739 1.00 68.87  ? 28  ILE A CA  1 
ATOM 6192 C C   . ILE E 4 16  ? 173.322 199.205 203.020 1.00 68.87  ? 28  ILE A C   1 
ATOM 6193 O O   . ILE E 4 16  ? 172.826 199.047 201.900 1.00 68.87  ? 28  ILE A O   1 
ATOM 6194 C CB  . ILE E 4 16  ? 173.023 197.133 204.445 1.00 68.87  ? 28  ILE A CB  1 
ATOM 6195 C CG1 . ILE E 4 16  ? 172.444 196.111 203.479 1.00 68.87  ? 28  ILE A CG1 1 
ATOM 6196 C CG2 . ILE E 4 16  ? 171.862 197.915 205.016 1.00 68.87  ? 28  ILE A CG2 1 
ATOM 6197 C CD1 . ILE E 4 16  ? 172.388 194.732 204.087 1.00 68.87  ? 28  ILE A CD1 1 
ATOM 6198 N N   . GLN E 4 17  ? 173.270 200.367 203.683 1.00 71.29  ? 29  GLN A N   1 
ATOM 6199 C CA  . GLN E 4 17  ? 172.832 201.593 203.011 1.00 71.29  ? 29  GLN A CA  1 
ATOM 6200 C C   . GLN E 4 17  ? 174.022 202.411 202.525 1.00 71.29  ? 29  GLN A C   1 
ATOM 6201 O O   . GLN E 4 17  ? 173.819 203.459 201.904 1.00 71.29  ? 29  GLN A O   1 
ATOM 6202 C CB  . GLN E 4 17  ? 171.953 202.413 203.964 1.00 71.29  ? 29  GLN A CB  1 
ATOM 6203 C CG  . GLN E 4 17  ? 171.106 203.489 203.312 1.00 71.29  ? 29  GLN A CG  1 
ATOM 6204 C CD  . GLN E 4 17  ? 170.923 204.693 204.210 1.00 71.29  ? 29  GLN A CD  1 
ATOM 6205 O OE1 . GLN E 4 17  ? 171.810 205.538 204.322 1.00 71.29  ? 29  GLN A OE1 1 
ATOM 6206 N NE2 . GLN E 4 17  ? 169.771 204.773 204.865 1.00 71.29  ? 29  GLN A NE2 1 
ATOM 6207 N N   . GLN E 4 18  ? 175.255 201.961 202.770 1.00 73.77  ? 30  GLN A N   1 
ATOM 6208 C CA  . GLN E 4 18  ? 176.432 202.649 202.259 1.00 73.77  ? 30  GLN A CA  1 
ATOM 6209 C C   . GLN E 4 18  ? 177.069 201.889 201.104 1.00 73.77  ? 30  GLN A C   1 
ATOM 6210 O O   . GLN E 4 18  ? 177.809 202.495 200.318 1.00 73.77  ? 30  GLN A O   1 
ATOM 6211 C CB  . GLN E 4 18  ? 177.458 202.869 203.379 1.00 73.77  ? 30  GLN A CB  1 
ATOM 6212 C CG  . GLN E 4 18  ? 178.538 203.888 203.059 1.00 73.77  ? 30  GLN A CG  1 
ATOM 6213 C CD  . GLN E 4 18  ? 179.877 203.529 203.671 1.00 73.77  ? 30  GLN A CD  1 
ATOM 6214 O OE1 . GLN E 4 18  ? 180.042 203.558 204.891 1.00 73.77  ? 30  GLN A OE1 1 
ATOM 6215 N NE2 . GLN E 4 18  ? 180.844 203.197 202.826 1.00 73.77  ? 30  GLN A NE2 1 
ATOM 6216 N N   . VAL E 4 19  ? 176.802 200.591 200.964 1.00 70.00  ? 31  VAL A N   1 
ATOM 6217 C CA  . VAL E 4 19  ? 177.130 199.846 199.752 1.00 70.00  ? 31  VAL A CA  1 
ATOM 6218 C C   . VAL E 4 19  ? 176.308 200.355 198.574 1.00 70.00  ? 31  VAL A C   1 
ATOM 6219 O O   . VAL E 4 19  ? 176.821 200.502 197.464 1.00 70.00  ? 31  VAL A O   1 
ATOM 6220 C CB  . VAL E 4 19  ? 176.948 198.324 199.957 1.00 70.00  ? 31  VAL A CB  1 
ATOM 6221 C CG1 . VAL E 4 19  ? 175.531 197.990 200.390 1.00 70.00  ? 31  VAL A CG1 1 
ATOM 6222 C CG2 . VAL E 4 19  ? 177.307 197.574 198.690 1.00 70.00  ? 31  VAL A CG2 1 
ATOM 6223 N N   . TYR E 4 20  ? 175.028 200.640 198.801 1.00 62.82  ? 32  TYR A N   1 
ATOM 6224 C CA  . TYR E 4 20  ? 174.260 201.427 197.851 1.00 62.82  ? 32  TYR A CA  1 
ATOM 6225 C C   . TYR E 4 20  ? 174.742 202.869 197.911 1.00 62.82  ? 32  TYR A C   1 
ATOM 6226 O O   . TYR E 4 20  ? 175.292 203.311 198.924 1.00 62.82  ? 32  TYR A O   1 
ATOM 6227 C CB  . TYR E 4 20  ? 172.761 201.331 198.155 1.00 62.82  ? 32  TYR A CB  1 
ATOM 6228 C CG  . TYR E 4 20  ? 172.144 199.964 197.890 1.00 62.82  ? 32  TYR A CG  1 
ATOM 6229 C CD1 . TYR E 4 20  ? 172.917 198.812 197.884 1.00 62.82  ? 32  TYR A CD1 1 
ATOM 6230 C CD2 . TYR E 4 20  ? 170.783 199.830 197.662 1.00 62.82  ? 32  TYR A CD2 1 
ATOM 6231 C CE1 . TYR E 4 20  ? 172.361 197.576 197.645 1.00 62.82  ? 32  TYR A CE1 1 
ATOM 6232 C CE2 . TYR E 4 20  ? 170.217 198.591 197.426 1.00 62.82  ? 32  TYR A CE2 1 
ATOM 6233 C CZ  . TYR E 4 20  ? 171.012 197.470 197.420 1.00 62.82  ? 32  TYR A CZ  1 
ATOM 6234 O OH  . TYR E 4 20  ? 170.460 196.233 197.186 1.00 62.82  ? 32  TYR A OH  1 
ATOM 6235 N N   . THR E 4 21  ? 174.547 203.601 196.812 1.00 76.76  ? 33  THR A N   1 
ATOM 6236 C CA  . THR E 4 21  ? 175.223 204.880 196.619 1.00 76.76  ? 33  THR A CA  1 
ATOM 6237 C C   . THR E 4 21  ? 176.723 204.641 196.712 1.00 76.76  ? 33  THR A C   1 
ATOM 6238 O O   . THR E 4 21  ? 177.370 205.084 197.667 1.00 76.76  ? 33  THR A O   1 
ATOM 6239 C CB  . THR E 4 21  ? 174.771 205.928 197.640 1.00 76.76  ? 33  THR A CB  1 
ATOM 6240 O OG1 . THR E 4 21  ? 173.363 205.800 197.868 1.00 76.76  ? 33  THR A OG1 1 
ATOM 6241 C CG2 . THR E 4 21  ? 175.072 207.328 197.131 1.00 76.76  ? 33  THR A CG2 1 
ATOM 6242 N N   . ARG E 4 22  ? 177.262 203.914 195.732 1.00 86.45  ? 34  ARG A N   1 
ATOM 6243 C CA  . ARG E 4 22  ? 178.608 203.360 195.815 1.00 86.45  ? 34  ARG A CA  1 
ATOM 6244 C C   . ARG E 4 22  ? 179.617 204.441 196.187 1.00 86.45  ? 34  ARG A C   1 
ATOM 6245 O O   . ARG E 4 22  ? 179.758 205.445 195.484 1.00 86.45  ? 34  ARG A O   1 
ATOM 6246 C CB  . ARG E 4 22  ? 178.986 202.732 194.472 1.00 86.45  ? 34  ARG A CB  1 
ATOM 6247 C CG  . ARG E 4 22  ? 178.527 201.286 194.271 1.00 86.45  ? 34  ARG A CG  1 
ATOM 6248 C CD  . ARG E 4 22  ? 179.229 200.246 195.140 1.00 86.45  ? 34  ARG A CD  1 
ATOM 6249 N NE  . ARG E 4 22  ? 180.684 200.348 195.121 1.00 86.45  ? 34  ARG A NE  1 
ATOM 6250 C CZ  . ARG E 4 22  ? 181.410 200.912 196.077 1.00 86.45  ? 34  ARG A CZ  1 
ATOM 6251 N NH1 . ARG E 4 22  ? 180.853 201.388 197.177 1.00 86.45  ? 34  ARG A NH1 1 
ATOM 6252 N NH2 . ARG E 4 22  ? 182.730 200.980 195.935 1.00 86.45  ? 34  ARG A NH2 1 
ATOM 6253 N N   . GLN E 4 23  ? 180.317 204.233 197.303 1.00 96.15  ? 35  GLN A N   1 
ATOM 6254 C CA  . GLN E 4 23  ? 181.275 205.215 197.798 1.00 96.15  ? 35  GLN A CA  1 
ATOM 6255 C C   . GLN E 4 23  ? 182.567 204.563 198.272 1.00 96.15  ? 35  GLN A C   1 
ATOM 6256 O O   . GLN E 4 23  ? 183.040 204.851 199.377 1.00 96.15  ? 35  GLN A O   1 
ATOM 6257 C CB  . GLN E 4 23  ? 180.667 206.041 198.935 1.00 96.15  ? 35  GLN A CB  1 
ATOM 6258 C CG  . GLN E 4 23  ? 179.884 207.257 198.470 1.00 96.15  ? 35  GLN A CG  1 
ATOM 6259 C CD  . GLN E 4 23  ? 178.791 207.657 199.442 1.00 96.15  ? 35  GLN A CD  1 
ATOM 6260 O OE1 . GLN E 4 23  ? 177.955 206.840 199.826 1.00 96.15  ? 35  GLN A OE1 1 
ATOM 6261 N NE2 . GLN E 4 23  ? 178.795 208.922 199.846 1.00 96.15  ? 35  GLN A NE2 1 
ATOM 6262 N N   . SER E 4 24  ? 183.141 203.685 197.448 1.00 103.59 ? 36  SER A N   1 
ATOM 6263 C CA  . SER E 4 24  ? 184.421 203.041 197.736 1.00 103.59 ? 36  SER A CA  1 
ATOM 6264 C C   . SER E 4 24  ? 184.386 202.290 199.062 1.00 103.59 ? 36  SER A C   1 
ATOM 6265 O O   . SER E 4 24  ? 185.119 202.636 199.994 1.00 103.59 ? 36  SER A O   1 
ATOM 6266 C CB  . SER E 4 24  ? 185.561 204.065 197.742 1.00 103.59 ? 36  SER A CB  1 
ATOM 6267 O OG  . SER E 4 24  ? 185.403 205.014 198.783 1.00 103.59 ? 36  SER A OG  1 
ATOM 6268 N N   . MET E 4 25  ? 183.528 201.276 199.158 1.00 90.27  ? 37  MET A N   1 
ATOM 6269 C CA  . MET E 4 25  ? 183.473 200.427 200.342 1.00 90.27  ? 37  MET A CA  1 
ATOM 6270 C C   . MET E 4 25  ? 184.821 199.766 200.595 1.00 90.27  ? 37  MET A C   1 
ATOM 6271 O O   . MET E 4 25  ? 185.286 198.967 199.778 1.00 90.27  ? 37  MET A O   1 
ATOM 6272 C CB  . MET E 4 25  ? 182.382 199.367 200.185 1.00 90.27  ? 37  MET A CB  1 
ATOM 6273 C CG  . MET E 4 25  ? 182.241 198.437 201.375 1.00 90.27  ? 37  MET A CG  1 
ATOM 6274 S SD  . MET E 4 25  ? 181.385 199.202 202.760 1.00 90.27  ? 37  MET A SD  1 
ATOM 6275 C CE  . MET E 4 25  ? 180.129 200.137 201.896 1.00 90.27  ? 37  MET A CE  1 
ATOM 6276 N N   . ALA E 4 26  ? 185.457 200.094 201.716 1.00 87.39  ? 38  ALA A N   1 
ATOM 6277 C CA  . ALA E 4 26  ? 186.754 199.511 202.036 1.00 87.39  ? 38  ALA A CA  1 
ATOM 6278 C C   . ALA E 4 26  ? 186.592 198.055 202.454 1.00 87.39  ? 38  ALA A C   1 
ATOM 6279 O O   . ALA E 4 26  ? 185.601 197.687 203.092 1.00 87.39  ? 38  ALA A O   1 
ATOM 6280 C CB  . ALA E 4 26  ? 187.436 200.308 203.145 1.00 87.39  ? 38  ALA A CB  1 
ATOM 6281 N N   . LYS E 4 27  ? 187.571 197.225 202.094 1.00 81.01  ? 39  LYS A N   1 
ATOM 6282 C CA  . LYS E 4 27  ? 187.552 195.818 202.473 1.00 81.01  ? 39  LYS A CA  1 
ATOM 6283 C C   . LYS E 4 27  ? 187.683 195.666 203.983 1.00 81.01  ? 39  LYS A C   1 
ATOM 6284 O O   . LYS E 4 27  ? 187.329 194.622 204.540 1.00 81.01  ? 39  LYS A O   1 
ATOM 6285 C CB  . LYS E 4 27  ? 188.669 195.049 201.763 1.00 81.01  ? 39  LYS A CB  1 
ATOM 6286 C CG  . LYS E 4 27  ? 188.733 195.288 200.265 1.00 81.01  ? 39  LYS A CG  1 
ATOM 6287 C CD  . LYS E 4 27  ? 190.170 195.311 199.769 1.00 81.01  ? 39  LYS A CD  1 
ATOM 6288 C CE  . LYS E 4 27  ? 190.233 195.562 198.272 1.00 81.01  ? 39  LYS A CE  1 
ATOM 6289 N NZ  . LYS E 4 27  ? 189.695 196.901 197.911 1.00 81.01  ? 39  LYS A NZ  1 
ATOM 6290 N N   . SER E 4 28  ? 188.196 196.701 204.651 1.00 77.67  ? 40  SER A N   1 
ATOM 6291 C CA  . SER E 4 28  ? 188.322 196.665 206.102 1.00 77.67  ? 40  SER A CA  1 
ATOM 6292 C C   . SER E 4 28  ? 186.974 196.537 206.796 1.00 77.67  ? 40  SER A C   1 
ATOM 6293 O O   . SER E 4 28  ? 186.899 195.959 207.886 1.00 77.67  ? 40  SER A O   1 
ATOM 6294 C CB  . SER E 4 28  ? 189.042 197.922 206.596 1.00 77.67  ? 40  SER A CB  1 
ATOM 6295 O OG  . SER E 4 28  ? 190.267 198.110 205.910 1.00 77.67  ? 40  SER A OG  1 
ATOM 6296 N N   . ARG E 4 29  ? 185.906 197.060 206.190 1.00 73.71  ? 41  ARG A N   1 
ATOM 6297 C CA  . ARG E 4 29  ? 184.573 196.977 206.764 1.00 73.71  ? 41  ARG A CA  1 
ATOM 6298 C C   . ARG E 4 29  ? 183.703 195.904 206.125 1.00 73.71  ? 41  ARG A C   1 
ATOM 6299 O O   . ARG E 4 29  ? 182.734 195.466 206.755 1.00 73.71  ? 41  ARG A O   1 
ATOM 6300 C CB  . ARG E 4 29  ? 183.863 198.340 206.661 1.00 73.71  ? 41  ARG A CB  1 
ATOM 6301 C CG  . ARG E 4 29  ? 182.462 198.379 207.252 1.00 73.71  ? 41  ARG A CG  1 
ATOM 6302 C CD  . ARG E 4 29  ? 181.842 199.759 207.166 1.00 73.71  ? 41  ARG A CD  1 
ATOM 6303 N NE  . ARG E 4 29  ? 181.329 200.189 208.461 1.00 73.71  ? 41  ARG A NE  1 
ATOM 6304 C CZ  . ARG E 4 29  ? 180.196 199.760 208.998 1.00 73.71  ? 41  ARG A CZ  1 
ATOM 6305 N NH1 . ARG E 4 29  ? 179.418 198.892 208.371 1.00 73.71  ? 41  ARG A NH1 1 
ATOM 6306 N NH2 . ARG E 4 29  ? 179.833 200.211 210.195 1.00 73.71  ? 41  ARG A NH2 1 
ATOM 6307 N N   . TYR E 4 30  ? 184.035 195.446 204.915 1.00 65.72  ? 42  TYR A N   1 
ATOM 6308 C CA  . TYR E 4 30  ? 183.244 194.402 204.271 1.00 65.72  ? 42  TYR A CA  1 
ATOM 6309 C C   . TYR E 4 30  ? 183.157 193.161 205.147 1.00 65.72  ? 42  TYR A C   1 
ATOM 6310 O O   . TYR E 4 30  ? 182.075 192.589 205.322 1.00 65.72  ? 42  TYR A O   1 
ATOM 6311 C CB  . TYR E 4 30  ? 183.845 194.066 202.904 1.00 65.72  ? 42  TYR A CB  1 
ATOM 6312 C CG  . TYR E 4 30  ? 183.114 193.000 202.110 1.00 65.72  ? 42  TYR A CG  1 
ATOM 6313 C CD1 . TYR E 4 30  ? 183.204 191.657 202.452 1.00 65.72  ? 42  TYR A CD1 1 
ATOM 6314 C CD2 . TYR E 4 30  ? 182.341 193.339 201.012 1.00 65.72  ? 42  TYR A CD2 1 
ATOM 6315 C CE1 . TYR E 4 30  ? 182.544 190.690 201.730 1.00 65.72  ? 42  TYR A CE1 1 
ATOM 6316 C CE2 . TYR E 4 30  ? 181.679 192.376 200.284 1.00 65.72  ? 42  TYR A CE2 1 
ATOM 6317 C CZ  . TYR E 4 30  ? 181.784 191.054 200.647 1.00 65.72  ? 42  TYR A CZ  1 
ATOM 6318 O OH  . TYR E 4 30  ? 181.125 190.091 199.923 1.00 65.72  ? 42  TYR A OH  1 
ATOM 6319 N N   . MET E 4 31  ? 184.281 192.733 205.712 1.00 68.91  ? 43  MET A N   1 
ATOM 6320 C CA  . MET E 4 31  ? 184.283 191.581 206.600 1.00 68.91  ? 43  MET A CA  1 
ATOM 6321 C C   . MET E 4 31  ? 183.618 191.874 207.938 1.00 68.91  ? 43  MET A C   1 
ATOM 6322 O O   . MET E 4 31  ? 183.253 190.935 208.652 1.00 68.91  ? 43  MET A O   1 
ATOM 6323 C CB  . MET E 4 31  ? 185.714 191.089 206.820 1.00 68.91  ? 43  MET A CB  1 
ATOM 6324 C CG  . MET E 4 31  ? 186.428 190.704 205.537 1.00 68.91  ? 43  MET A CG  1 
ATOM 6325 S SD  . MET E 4 31  ? 185.852 189.137 204.863 1.00 68.91  ? 43  MET A SD  1 
ATOM 6326 C CE  . MET E 4 31  ? 185.727 188.157 206.353 1.00 68.91  ? 43  MET A CE  1 
ATOM 6327 N N   . GLU E 4 32  ? 183.452 193.148 208.289 1.00 71.77  ? 44  GLU A N   1 
ATOM 6328 C CA  . GLU E 4 32  ? 182.671 193.517 209.462 1.00 71.77  ? 44  GLU A CA  1 
ATOM 6329 C C   . GLU E 4 32  ? 181.177 193.383 209.190 1.00 71.77  ? 44  GLU A C   1 
ATOM 6330 O O   . GLU E 4 32  ? 180.397 193.114 210.107 1.00 71.77  ? 44  GLU A O   1 
ATOM 6331 C CB  . GLU E 4 32  ? 183.003 194.947 209.895 1.00 71.77  ? 44  GLU A CB  1 
ATOM 6332 C CG  . GLU E 4 32  ? 184.194 195.058 210.827 1.00 71.77  ? 44  GLU A CG  1 
ATOM 6333 C CD  . GLU E 4 32  ? 184.791 196.452 210.841 1.00 71.77  ? 44  GLU A CD  1 
ATOM 6334 O OE1 . GLU E 4 32  ? 186.015 196.579 210.631 1.00 71.77  ? 44  GLU A OE1 1 
ATOM 6335 O OE2 . GLU E 4 32  ? 184.036 197.421 211.067 1.00 71.77  ? 44  GLU A OE2 1 
ATOM 6336 N N   . LEU E 4 33  ? 180.767 193.570 207.935 1.00 65.89  ? 45  LEU A N   1 
ATOM 6337 C CA  . LEU E 4 33  ? 179.366 193.431 207.565 1.00 65.89  ? 45  LEU A CA  1 
ATOM 6338 C C   . LEU E 4 33  ? 179.039 191.962 207.332 1.00 65.89  ? 45  LEU A C   1 
ATOM 6339 O O   . LEU E 4 33  ? 177.866 191.579 207.277 1.00 65.89  ? 45  LEU A O   1 
ATOM 6340 C CB  . LEU E 4 33  ? 179.054 194.255 206.317 1.00 65.89  ? 45  LEU A CB  1 
ATOM 6341 C CG  . LEU E 4 33  ? 178.955 195.768 206.512 1.00 65.89  ? 45  LEU A CG  1 
ATOM 6342 C CD1 . LEU E 4 33  ? 179.115 196.486 205.182 1.00 65.89  ? 45  LEU A CD1 1 
ATOM 6343 C CD2 . LEU E 4 33  ? 177.650 196.157 207.176 1.00 65.89  ? 45  LEU A CD2 1 
ATOM 6344 N N   . TYR E 4 34  ? 180.074 191.135 207.195 1.00 61.45  ? 46  TYR A N   1 
ATOM 6345 C CA  . TYR E 4 34  ? 179.913 189.687 207.131 1.00 61.45  ? 46  TYR A CA  1 
ATOM 6346 C C   . TYR E 4 34  ? 179.892 189.091 208.530 1.00 61.45  ? 46  TYR A C   1 
ATOM 6347 O O   . TYR E 4 34  ? 178.988 188.312 208.848 1.00 61.45  ? 46  TYR A O   1 
ATOM 6348 C CB  . TYR E 4 34  ? 181.039 189.072 206.281 1.00 61.45  ? 46  TYR A CB  1 
ATOM 6349 C CG  . TYR E 4 34  ? 180.866 187.615 205.868 1.00 61.45  ? 46  TYR A CG  1 
ATOM 6350 C CD1 . TYR E 4 34  ? 180.055 186.747 206.580 1.00 61.45  ? 46  TYR A CD1 1 
ATOM 6351 C CD2 . TYR E 4 34  ? 181.535 187.110 204.765 1.00 61.45  ? 46  TYR A CD2 1 
ATOM 6352 C CE1 . TYR E 4 34  ? 179.908 185.431 206.208 1.00 61.45  ? 46  TYR A CE1 1 
ATOM 6353 C CE2 . TYR E 4 34  ? 181.389 185.792 204.384 1.00 61.45  ? 46  TYR A CE2 1 
ATOM 6354 C CZ  . TYR E 4 34  ? 180.578 184.958 205.110 1.00 61.45  ? 46  TYR A CZ  1 
ATOM 6355 O OH  . TYR E 4 34  ? 180.430 183.644 204.737 1.00 61.45  ? 46  TYR A OH  1 
ATOM 6356 N N   . THR E 4 35  ? 180.850 189.454 209.383 1.00 65.40  ? 47  THR A N   1 
ATOM 6357 C CA  . THR E 4 35  ? 180.931 188.914 210.734 1.00 65.40  ? 47  THR A CA  1 
ATOM 6358 C C   . THR E 4 35  ? 179.614 189.107 211.471 1.00 65.40  ? 47  THR A C   1 
ATOM 6359 O O   . THR E 4 35  ? 179.218 188.260 212.277 1.00 65.40  ? 47  THR A O   1 
ATOM 6360 C CB  . THR E 4 35  ? 182.079 189.565 211.505 1.00 65.40  ? 47  THR A CB  1 
ATOM 6361 O OG1 . THR E 4 35  ? 183.185 189.774 210.620 1.00 65.40  ? 47  THR A OG1 1 
ATOM 6362 C CG2 . THR E 4 35  ? 182.518 188.673 212.655 1.00 65.40  ? 47  THR A CG2 1 
ATOM 6363 N N   . HIS E 4 36  ? 178.926 190.217 211.202 1.00 67.99  ? 48  HIS A N   1 
ATOM 6364 C CA  . HIS E 4 36  ? 177.607 190.426 211.789 1.00 67.99  ? 48  HIS A CA  1 
ATOM 6365 C C   . HIS E 4 36  ? 176.603 189.410 211.257 1.00 67.99  ? 48  HIS A C   1 
ATOM 6366 O O   . HIS E 4 36  ? 175.992 188.660 212.026 1.00 67.99  ? 48  HIS A O   1 
ATOM 6367 C CB  . HIS E 4 36  ? 177.125 191.850 211.510 1.00 67.99  ? 48  HIS A CB  1 
ATOM 6368 C CG  . HIS E 4 36  ? 177.877 192.903 212.260 1.00 67.99  ? 48  HIS A CG  1 
ATOM 6369 N ND1 . HIS E 4 36  ? 179.242 193.058 212.162 1.00 67.99  ? 48  HIS A ND1 1 
ATOM 6370 C CD2 . HIS E 4 36  ? 177.451 193.856 213.121 1.00 67.99  ? 48  HIS A CD2 1 
ATOM 6371 C CE1 . HIS E 4 36  ? 179.625 194.062 212.929 1.00 67.99  ? 48  HIS A CE1 1 
ATOM 6372 N NE2 . HIS E 4 36  ? 178.557 194.564 213.523 1.00 67.99  ? 48  HIS A NE2 1 
ATOM 6373 N N   . VAL E 4 37  ? 176.445 189.348 209.936 1.00 59.95  ? 49  VAL A N   1 
ATOM 6374 C CA  . VAL E 4 37  ? 175.406 188.531 209.317 1.00 59.95  ? 49  VAL A CA  1 
ATOM 6375 C C   . VAL E 4 37  ? 175.691 187.061 209.593 1.00 59.95  ? 49  VAL A C   1 
ATOM 6376 O O   . VAL E 4 37  ? 174.768 186.268 209.815 1.00 59.95  ? 49  VAL A O   1 
ATOM 6377 C CB  . VAL E 4 37  ? 175.302 188.815 207.808 1.00 59.95  ? 49  VAL A CB  1 
ATOM 6378 C CG1 . VAL E 4 37  ? 174.800 187.596 207.064 1.00 59.95  ? 49  VAL A CG1 1 
ATOM 6379 C CG2 . VAL E 4 37  ? 174.391 190.004 207.562 1.00 59.95  ? 49  VAL A CG2 1 
ATOM 6380 N N   . TYR E 4 38  ? 176.970 186.689 209.597 1.00 67.88  ? 50  TYR A N   1 
ATOM 6381 C CA  . TYR E 4 38  ? 177.381 185.345 209.977 1.00 67.88  ? 50  TYR A CA  1 
ATOM 6382 C C   . TYR E 4 38  ? 176.973 185.018 211.407 1.00 67.88  ? 50  TYR A C   1 
ATOM 6383 O O   . TYR E 4 38  ? 176.304 184.010 211.641 1.00 67.88  ? 50  TYR A O   1 
ATOM 6384 C CB  . TYR E 4 38  ? 178.896 185.181 209.810 1.00 67.88  ? 50  TYR A CB  1 
ATOM 6385 C CG  . TYR E 4 38  ? 179.438 183.926 210.447 1.00 67.88  ? 50  TYR A CG  1 
ATOM 6386 C CD1 . TYR E 4 38  ? 179.039 182.672 210.012 1.00 67.88  ? 50  TYR A CD1 1 
ATOM 6387 C CD2 . TYR E 4 38  ? 180.342 183.996 211.495 1.00 67.88  ? 50  TYR A CD2 1 
ATOM 6388 C CE1 . TYR E 4 38  ? 179.532 181.524 210.597 1.00 67.88  ? 50  TYR A CE1 1 
ATOM 6389 C CE2 . TYR E 4 38  ? 180.839 182.854 212.087 1.00 67.88  ? 50  TYR A CE2 1 
ATOM 6390 C CZ  . TYR E 4 38  ? 180.431 181.622 211.635 1.00 67.88  ? 50  TYR A CZ  1 
ATOM 6391 O OH  . TYR E 4 38  ? 180.926 180.483 212.225 1.00 67.88  ? 50  TYR A OH  1 
ATOM 6392 N N   . ASN E 4 39  ? 177.335 185.870 212.369 1.00 73.22  ? 51  ASN A N   1 
ATOM 6393 C CA  . ASN E 4 39  ? 176.958 185.632 213.759 1.00 73.22  ? 51  ASN A CA  1 
ATOM 6394 C C   . ASN E 4 39  ? 175.442 185.613 213.922 1.00 73.22  ? 51  ASN A C   1 
ATOM 6395 O O   . ASN E 4 39  ? 174.899 184.831 214.710 1.00 73.22  ? 51  ASN A O   1 
ATOM 6396 C CB  . ASN E 4 39  ? 177.592 186.690 214.664 1.00 73.22  ? 51  ASN A CB  1 
ATOM 6397 C CG  . ASN E 4 39  ? 179.088 186.498 214.831 1.00 73.22  ? 51  ASN A CG  1 
ATOM 6398 O OD1 . ASN E 4 39  ? 179.533 185.603 215.549 1.00 73.22  ? 51  ASN A OD1 1 
ATOM 6399 N ND2 . ASN E 4 39  ? 179.870 187.344 214.178 1.00 73.22  ? 51  ASN A ND2 1 
ATOM 6400 N N   . TYR E 4 40  ? 174.745 186.473 213.181 1.00 78.93  ? 52  TYR A N   1 
ATOM 6401 C CA  . TYR E 4 40  ? 173.287 186.529 213.188 1.00 78.93  ? 52  TYR A CA  1 
ATOM 6402 C C   . TYR E 4 40  ? 172.698 185.170 212.827 1.00 78.93  ? 52  TYR A C   1 
ATOM 6403 O O   . TYR E 4 40  ? 171.635 184.794 213.331 1.00 78.93  ? 52  TYR A O   1 
ATOM 6404 C CB  . TYR E 4 40  ? 172.815 187.607 212.204 1.00 78.93  ? 52  TYR A CB  1 
ATOM 6405 C CG  . TYR E 4 40  ? 171.389 188.113 212.353 1.00 78.93  ? 52  TYR A CG  1 
ATOM 6406 C CD1 . TYR E 4 40  ? 170.438 187.413 213.077 1.00 78.93  ? 52  TYR A CD1 1 
ATOM 6407 C CD2 . TYR E 4 40  ? 170.993 189.289 211.731 1.00 78.93  ? 52  TYR A CD2 1 
ATOM 6408 C CE1 . TYR E 4 40  ? 169.145 187.874 213.187 1.00 78.93  ? 52  TYR A CE1 1 
ATOM 6409 C CE2 . TYR E 4 40  ? 169.696 189.758 211.837 1.00 78.93  ? 52  TYR A CE2 1 
ATOM 6410 C CZ  . TYR E 4 40  ? 168.777 189.046 212.571 1.00 78.93  ? 52  TYR A CZ  1 
ATOM 6411 O OH  . TYR E 4 40  ? 167.483 189.501 212.688 1.00 78.93  ? 52  TYR A OH  1 
ATOM 6412 N N   . CYS E 4 41  ? 173.389 184.408 211.977 1.00 81.09  ? 53  CYS A N   1 
ATOM 6413 C CA  . CYS E 4 41  ? 172.849 183.148 211.484 1.00 81.09  ? 53  CYS A CA  1 
ATOM 6414 C C   . CYS E 4 41  ? 173.454 181.920 212.155 1.00 81.09  ? 53  CYS A C   1 
ATOM 6415 O O   . CYS E 4 41  ? 173.097 180.796 211.784 1.00 81.09  ? 53  CYS A O   1 
ATOM 6416 C CB  . CYS E 4 41  ? 173.032 183.044 209.967 1.00 81.09  ? 53  CYS A CB  1 
ATOM 6417 S SG  . CYS E 4 41  ? 171.706 182.139 209.141 1.00 81.09  ? 53  CYS A SG  1 
ATOM 6418 N N   . THR E 4 42  ? 174.350 182.088 213.128 1.00 79.01  ? 54  THR A N   1 
ATOM 6419 C CA  . THR E 4 42  ? 174.913 180.942 213.851 1.00 79.01  ? 54  THR A CA  1 
ATOM 6420 C C   . THR E 4 42  ? 174.792 181.194 215.357 1.00 79.01  ? 54  THR A C   1 
ATOM 6421 O O   . THR E 4 42  ? 175.719 181.681 216.010 1.00 79.01  ? 54  THR A O   1 
ATOM 6422 C CB  . THR E 4 42  ? 176.350 180.655 213.408 1.00 79.01  ? 54  THR A CB  1 
ATOM 6423 O OG1 . THR E 4 42  ? 176.862 179.523 214.122 1.00 79.01  ? 54  THR A OG1 1 
ATOM 6424 C CG2 . THR E 4 42  ? 177.279 181.858 213.580 1.00 79.01  ? 54  THR A CG2 1 
ATOM 6425 N N   . SER E 4 43  ? 173.634 180.833 215.909 1.00 103.26 ? 55  SER A N   1 
ATOM 6426 C CA  . SER E 4 43  ? 173.376 180.947 217.339 1.00 103.26 ? 55  SER A CA  1 
ATOM 6427 C C   . SER E 4 43  ? 172.054 180.277 217.688 1.00 103.26 ? 55  SER A C   1 
ATOM 6428 O O   . SER E 4 43  ? 171.324 179.834 216.796 1.00 103.26 ? 55  SER A O   1 
ATOM 6429 C CB  . SER E 4 43  ? 173.351 182.414 217.775 1.00 103.26 ? 55  SER A CB  1 
ATOM 6430 O OG  . SER E 4 43  ? 173.545 182.534 219.173 1.00 103.26 ? 55  SER A OG  1 
ATOM 6431 N N   . VAL E 4 44  ? 171.737 180.199 218.979 1.00 119.91 ? 56  VAL A N   1 
ATOM 6432 C CA  . VAL E 4 44  ? 170.435 179.715 219.422 1.00 119.91 ? 56  VAL A CA  1 
ATOM 6433 C C   . VAL E 4 44  ? 169.955 180.618 220.551 1.00 119.91 ? 56  VAL A C   1 
ATOM 6434 O O   . VAL E 4 44  ? 170.489 180.578 221.665 1.00 119.91 ? 56  VAL A O   1 
ATOM 6435 C CB  . VAL E 4 44  ? 170.491 178.237 219.857 1.00 119.91 ? 56  VAL A CB  1 
ATOM 6436 C CG1 . VAL E 4 44  ? 169.323 177.898 220.777 1.00 119.91 ? 56  VAL A CG1 1 
ATOM 6437 C CG2 . VAL E 4 44  ? 170.488 177.325 218.640 1.00 119.91 ? 56  VAL A CG2 1 
ATOM 6438 N N   . HIS E 4 45  ? 168.960 181.451 220.260 1.00 123.07 ? 57  HIS A N   1 
ATOM 6439 C CA  . HIS E 4 45  ? 168.420 182.397 221.231 1.00 123.07 ? 57  HIS A CA  1 
ATOM 6440 C C   . HIS E 4 45  ? 167.123 183.018 220.719 1.00 123.07 ? 57  HIS A C   1 
ATOM 6441 O O   . HIS E 4 45  ? 167.016 183.379 219.547 1.00 123.07 ? 57  HIS A O   1 
ATOM 6442 C CB  . HIS E 4 45  ? 169.440 183.497 221.550 1.00 123.07 ? 57  HIS A CB  1 
ATOM 6443 C CG  . HIS E 4 45  ? 169.686 184.447 220.419 1.00 123.07 ? 57  HIS A CG  1 
ATOM 6444 N ND1 . HIS E 4 45  ? 169.557 184.083 219.096 1.00 123.07 ? 57  HIS A ND1 1 
ATOM 6445 C CD2 . HIS E 4 45  ? 170.053 185.751 220.415 1.00 123.07 ? 57  HIS A CD2 1 
ATOM 6446 C CE1 . HIS E 4 45  ? 169.835 185.120 218.326 1.00 123.07 ? 57  HIS A CE1 1 
ATOM 6447 N NE2 . HIS E 4 45  ? 170.139 186.145 219.102 1.00 123.07 ? 57  HIS A NE2 1 
ATOM 6448 N N   . GLN E 4 70  ? 168.647 181.352 217.396 1.00 114.58 ? 82  GLN A N   1 
ATOM 6449 C CA  . GLN E 4 70  ? 168.044 180.350 216.528 1.00 114.58 ? 82  GLN A CA  1 
ATOM 6450 C C   . GLN E 4 70  ? 167.753 180.984 215.180 1.00 114.58 ? 82  GLN A C   1 
ATOM 6451 O O   . GLN E 4 70  ? 166.607 181.010 214.735 1.00 114.58 ? 82  GLN A O   1 
ATOM 6452 C CB  . GLN E 4 70  ? 166.765 179.791 217.151 1.00 114.58 ? 82  GLN A CB  1 
ATOM 6453 C CG  . GLN E 4 70  ? 165.931 180.832 217.879 1.00 114.58 ? 82  GLN A CG  1 
ATOM 6454 C CD  . GLN E 4 70  ? 164.942 180.218 218.847 1.00 114.58 ? 82  GLN A CD  1 
ATOM 6455 O OE1 . GLN E 4 70  ? 163.756 180.090 218.541 1.00 114.58 ? 82  GLN A OE1 1 
ATOM 6456 N NE2 . GLN E 4 70  ? 165.424 179.838 220.024 1.00 114.58 ? 82  GLN A NE2 1 
ATOM 6457 N N   . PHE E 4 71  ? 168.807 181.538 214.572 1.00 107.24 ? 83  PHE A N   1 
ATOM 6458 C CA  . PHE E 4 71  ? 168.782 182.327 213.340 1.00 107.24 ? 83  PHE A CA  1 
ATOM 6459 C C   . PHE E 4 71  ? 167.627 183.322 213.352 1.00 107.24 ? 83  PHE A C   1 
ATOM 6460 O O   . PHE E 4 71  ? 167.170 183.756 212.289 1.00 107.24 ? 83  PHE A O   1 
ATOM 6461 C CB  . PHE E 4 71  ? 168.718 181.443 212.080 1.00 107.24 ? 83  PHE A CB  1 
ATOM 6462 C CG  . PHE E 4 71  ? 167.877 180.203 212.221 1.00 107.24 ? 83  PHE A CG  1 
ATOM 6463 C CD1 . PHE E 4 71  ? 166.517 180.239 211.950 1.00 107.24 ? 83  PHE A CD1 1 
ATOM 6464 C CD2 . PHE E 4 71  ? 168.452 178.992 212.569 1.00 107.24 ? 83  PHE A CD2 1 
ATOM 6465 C CE1 . PHE E 4 71  ? 165.740 179.103 212.069 1.00 107.24 ? 83  PHE A CE1 1 
ATOM 6466 C CE2 . PHE E 4 71  ? 167.679 177.850 212.689 1.00 107.24 ? 83  PHE A CE2 1 
ATOM 6467 C CZ  . PHE E 4 71  ? 166.322 177.906 212.435 1.00 107.24 ? 83  PHE A CZ  1 
ATOM 6468 N N   . VAL E 4 72  ? 167.202 183.719 214.556 1.00 103.11 ? 84  VAL A N   1 
ATOM 6469 C CA  . VAL E 4 72  ? 166.046 184.575 214.817 1.00 103.11 ? 84  VAL A CA  1 
ATOM 6470 C C   . VAL E 4 72  ? 164.978 184.411 213.742 1.00 103.11 ? 84  VAL A C   1 
ATOM 6471 O O   . VAL E 4 72  ? 164.572 185.385 213.098 1.00 103.11 ? 84  VAL A O   1 
ATOM 6472 C CB  . VAL E 4 72  ? 166.481 186.043 214.961 1.00 103.11 ? 84  VAL A CB  1 
ATOM 6473 C CG1 . VAL E 4 72  ? 165.436 186.832 215.739 1.00 103.11 ? 84  VAL A CG1 1 
ATOM 6474 C CG2 . VAL E 4 72  ? 167.819 186.107 215.671 1.00 103.11 ? 84  VAL A CG2 1 
ATOM 6475 N N   . GLY E 4 73  ? 164.527 183.176 213.534 1.00 94.45  ? 85  GLY A N   1 
ATOM 6476 C CA  . GLY E 4 73  ? 163.514 182.889 212.538 1.00 94.45  ? 85  GLY A CA  1 
ATOM 6477 C C   . GLY E 4 73  ? 163.906 183.265 211.123 1.00 94.45  ? 85  GLY A C   1 
ATOM 6478 O O   . GLY E 4 73  ? 164.864 182.721 210.568 1.00 94.45  ? 85  GLY A O   1 
ATOM 6479 N N   . LEU E 4 74  ? 163.167 184.203 210.532 1.00 79.99  ? 86  LEU A N   1 
ATOM 6480 C CA  . LEU E 4 74  ? 163.390 184.605 209.149 1.00 79.99  ? 86  LEU A CA  1 
ATOM 6481 C C   . LEU E 4 74  ? 163.380 186.121 209.020 1.00 79.99  ? 86  LEU A C   1 
ATOM 6482 O O   . LEU E 4 74  ? 163.276 186.656 207.911 1.00 79.99  ? 86  LEU A O   1 
ATOM 6483 C CB  . LEU E 4 74  ? 162.331 183.976 208.237 1.00 79.99  ? 86  LEU A CB  1 
ATOM 6484 C CG  . LEU E 4 74  ? 160.839 184.246 208.468 1.00 79.99  ? 86  LEU A CG  1 
ATOM 6485 C CD1 . LEU E 4 74  ? 160.348 185.493 207.740 1.00 79.99  ? 86  LEU A CD1 1 
ATOM 6486 C CD2 . LEU E 4 74  ? 160.018 183.033 208.057 1.00 79.99  ? 86  LEU A CD2 1 
ATOM 6487 N N   . GLU E 4 75  ? 163.505 186.817 210.148 1.00 79.96  ? 87  GLU A N   1 
ATOM 6488 C CA  . GLU E 4 75  ? 163.308 188.259 210.194 1.00 79.96  ? 87  GLU A CA  1 
ATOM 6489 C C   . GLU E 4 75  ? 164.296 189.002 209.300 1.00 79.96  ? 87  GLU A C   1 
ATOM 6490 O O   . GLU E 4 75  ? 163.911 189.958 208.620 1.00 79.96  ? 87  GLU A O   1 
ATOM 6491 C CB  . GLU E 4 75  ? 163.399 188.756 211.639 1.00 79.96  ? 87  GLU A CB  1 
ATOM 6492 C CG  . GLU E 4 75  ? 164.002 190.137 211.800 1.00 79.96  ? 87  GLU A CG  1 
ATOM 6493 C CD  . GLU E 4 75  ? 164.036 190.593 213.245 1.00 79.96  ? 87  GLU A CD  1 
ATOM 6494 O OE1 . GLU E 4 75  ? 163.977 189.729 214.145 1.00 79.96  ? 87  GLU A OE1 1 
ATOM 6495 O OE2 . GLU E 4 75  ? 164.110 191.817 213.480 1.00 79.96  ? 87  GLU A OE2 1 
ATOM 6496 N N   . LEU E 4 76  ? 165.560 188.570 209.276 1.00 68.08  ? 88  LEU A N   1 
ATOM 6497 C CA  . LEU E 4 76  ? 166.571 189.250 208.469 1.00 68.08  ? 88  LEU A CA  1 
ATOM 6498 C C   . LEU E 4 76  ? 166.171 189.295 207.000 1.00 68.08  ? 88  LEU A C   1 
ATOM 6499 O O   . LEU E 4 76  ? 166.452 190.278 206.308 1.00 68.08  ? 88  LEU A O   1 
ATOM 6500 C CB  . LEU E 4 76  ? 167.940 188.579 208.607 1.00 68.08  ? 88  LEU A CB  1 
ATOM 6501 C CG  . LEU E 4 76  ? 169.095 189.418 208.041 1.00 68.08  ? 88  LEU A CG  1 
ATOM 6502 C CD1 . LEU E 4 76  ? 168.984 190.869 208.484 1.00 68.08  ? 88  LEU A CD1 1 
ATOM 6503 C CD2 . LEU E 4 76  ? 170.461 188.851 208.390 1.00 68.08  ? 88  LEU A CD2 1 
ATOM 6504 N N   . TYR E 4 77  ? 165.525 188.238 206.512 1.00 65.59  ? 89  TYR A N   1 
ATOM 6505 C CA  . TYR E 4 77  ? 165.035 188.236 205.140 1.00 65.59  ? 89  TYR A CA  1 
ATOM 6506 C C   . TYR E 4 77  ? 163.997 189.332 204.953 1.00 65.59  ? 89  TYR A C   1 
ATOM 6507 O O   . TYR E 4 77  ? 164.029 190.068 203.962 1.00 65.59  ? 89  TYR A O   1 
ATOM 6508 C CB  . TYR E 4 77  ? 164.436 186.878 204.778 1.00 65.59  ? 89  TYR A CB  1 
ATOM 6509 C CG  . TYR E 4 77  ? 164.262 186.671 203.294 1.00 65.59  ? 89  TYR A CG  1 
ATOM 6510 C CD1 . TYR E 4 77  ? 165.311 186.897 202.417 1.00 65.59  ? 89  TYR A CD1 1 
ATOM 6511 C CD2 . TYR E 4 77  ? 163.046 186.264 202.767 1.00 65.59  ? 89  TYR A CD2 1 
ATOM 6512 C CE1 . TYR E 4 77  ? 165.158 186.711 201.061 1.00 65.59  ? 89  TYR A CE1 1 
ATOM 6513 C CE2 . TYR E 4 77  ? 162.882 186.079 201.412 1.00 65.59  ? 89  TYR A CE2 1 
ATOM 6514 C CZ  . TYR E 4 77  ? 163.941 186.303 200.564 1.00 65.59  ? 89  TYR A CZ  1 
ATOM 6515 O OH  . TYR E 4 77  ? 163.785 186.118 199.211 1.00 65.59  ? 89  TYR A OH  1 
ATOM 6516 N N   . LYS E 4 78  ? 163.067 189.442 205.903 1.00 69.74  ? 90  LYS A N   1 
ATOM 6517 C CA  . LYS E 4 78  ? 162.021 190.453 205.829 1.00 69.74  ? 90  LYS A CA  1 
ATOM 6518 C C   . LYS E 4 78  ? 162.593 191.862 205.935 1.00 69.74  ? 90  LYS A C   1 
ATOM 6519 O O   . LYS E 4 78  ? 162.190 192.768 205.199 1.00 69.74  ? 90  LYS A O   1 
ATOM 6520 C CB  . LYS E 4 78  ? 160.983 190.204 206.927 1.00 69.74  ? 90  LYS A CB  1 
ATOM 6521 C CG  . LYS E 4 78  ? 159.802 191.156 206.892 1.00 69.74  ? 90  LYS A CG  1 
ATOM 6522 C CD  . LYS E 4 78  ? 158.561 190.512 207.486 1.00 69.74  ? 90  LYS A CD  1 
ATOM 6523 C CE  . LYS E 4 78  ? 157.765 189.768 206.427 1.00 69.74  ? 90  LYS A CE  1 
ATOM 6524 N NZ  . LYS E 4 78  ? 157.174 190.695 205.422 1.00 69.74  ? 90  LYS A NZ  1 
ATOM 6525 N N   . ARG E 4 79  ? 163.540 192.060 206.854 1.00 73.19  ? 91  ARG A N   1 
ATOM 6526 C CA  . ARG E 4 79  ? 164.130 193.384 207.027 1.00 73.19  ? 91  ARG A CA  1 
ATOM 6527 C C   . ARG E 4 79  ? 164.969 193.777 205.819 1.00 73.19  ? 91  ARG A C   1 
ATOM 6528 O O   . ARG E 4 79  ? 165.166 194.968 205.550 1.00 73.19  ? 91  ARG A O   1 
ATOM 6529 C CB  . ARG E 4 79  ? 164.970 193.424 208.303 1.00 73.19  ? 91  ARG A CB  1 
ATOM 6530 C CG  . ARG E 4 79  ? 164.245 192.901 209.529 1.00 73.19  ? 91  ARG A CG  1 
ATOM 6531 C CD  . ARG E 4 79  ? 163.626 194.013 210.356 1.00 73.19  ? 91  ARG A CD  1 
ATOM 6532 N NE  . ARG E 4 79  ? 164.414 194.294 211.550 1.00 73.19  ? 91  ARG A NE  1 
ATOM 6533 C CZ  . ARG E 4 79  ? 164.323 195.407 212.264 1.00 73.19  ? 91  ARG A CZ  1 
ATOM 6534 N NH1 . ARG E 4 79  ? 163.483 196.374 211.933 1.00 73.19  ? 91  ARG A NH1 1 
ATOM 6535 N NH2 . ARG E 4 79  ? 165.093 195.554 213.338 1.00 73.19  ? 91  ARG A NH2 1 
ATOM 6536 N N   . LEU E 4 80  ? 165.477 192.792 205.079 1.00 62.68  ? 92  LEU A N   1 
ATOM 6537 C CA  . LEU E 4 80  ? 166.223 193.050 203.857 1.00 62.68  ? 92  LEU A CA  1 
ATOM 6538 C C   . LEU E 4 80  ? 165.316 193.210 202.646 1.00 62.68  ? 92  LEU A C   1 
ATOM 6539 O O   . LEU E 4 80  ? 165.799 193.539 201.557 1.00 62.68  ? 92  LEU A O   1 
ATOM 6540 C CB  . LEU E 4 80  ? 167.242 191.937 203.613 1.00 62.68  ? 92  LEU A CB  1 
ATOM 6541 C CG  . LEU E 4 80  ? 168.647 192.243 204.129 1.00 62.68  ? 92  LEU A CG  1 
ATOM 6542 C CD1 . LEU E 4 80  ? 169.690 191.469 203.350 1.00 62.68  ? 92  LEU A CD1 1 
ATOM 6543 C CD2 . LEU E 4 80  ? 168.923 193.735 204.057 1.00 62.68  ? 92  LEU A CD2 1 
ATOM 6544 N N   . LYS E 4 81  ? 164.016 192.979 202.811 1.00 63.92  ? 93  LYS A N   1 
ATOM 6545 C CA  . LYS E 4 81  ? 163.036 193.280 201.780 1.00 63.92  ? 93  LYS A CA  1 
ATOM 6546 C C   . LYS E 4 81  ? 162.479 194.690 201.904 1.00 63.92  ? 93  LYS A C   1 
ATOM 6547 O O   . LYS E 4 81  ? 162.116 195.289 200.887 1.00 63.92  ? 93  LYS A O   1 
ATOM 6548 C CB  . LYS E 4 81  ? 161.885 192.267 201.837 1.00 63.92  ? 93  LYS A CB  1 
ATOM 6549 C CG  . LYS E 4 81  ? 160.832 192.442 200.758 1.00 63.92  ? 93  LYS A CG  1 
ATOM 6550 C CD  . LYS E 4 81  ? 160.458 191.110 200.134 1.00 63.92  ? 93  LYS A CD  1 
ATOM 6551 C CE  . LYS E 4 81  ? 159.638 190.270 201.097 1.00 63.92  ? 93  LYS A CE  1 
ATOM 6552 N NZ  . LYS E 4 81  ? 159.538 188.854 200.653 1.00 63.92  ? 93  LYS A NZ  1 
ATOM 6553 N N   . GLU E 4 82  ? 162.424 195.238 203.117 1.00 66.29  ? 94  GLU A N   1 
ATOM 6554 C CA  . GLU E 4 82  ? 161.913 196.583 203.340 1.00 66.29  ? 94  GLU A CA  1 
ATOM 6555 C C   . GLU E 4 82  ? 162.903 197.650 202.889 1.00 66.29  ? 94  GLU A C   1 
ATOM 6556 O O   . GLU E 4 82  ? 162.506 198.651 202.285 1.00 66.29  ? 94  GLU A O   1 
ATOM 6557 C CB  . GLU E 4 82  ? 161.571 196.778 204.822 1.00 66.29  ? 94  GLU A CB  1 
ATOM 6558 C CG  . GLU E 4 82  ? 160.557 195.789 205.404 1.00 66.29  ? 94  GLU A CG  1 
ATOM 6559 C CD  . GLU E 4 82  ? 159.151 195.911 204.825 1.00 66.29  ? 94  GLU A CD  1 
ATOM 6560 O OE1 . GLU E 4 82  ? 158.215 195.376 205.455 1.00 66.29  ? 94  GLU A OE1 1 
ATOM 6561 O OE2 . GLU E 4 82  ? 158.961 196.543 203.765 1.00 66.29  ? 94  GLU A OE2 1 
ATOM 6562 N N   . PHE E 4 83  ? 164.191 197.458 203.183 1.00 59.87  ? 95  PHE A N   1 
ATOM 6563 C CA  . PHE E 4 83  ? 165.186 198.449 202.791 1.00 59.87  ? 95  PHE A CA  1 
ATOM 6564 C C   . PHE E 4 83  ? 165.300 198.541 201.275 1.00 59.87  ? 95  PHE A C   1 
ATOM 6565 O O   . PHE E 4 83  ? 165.432 199.637 200.719 1.00 59.87  ? 95  PHE A O   1 
ATOM 6566 C CB  . PHE E 4 83  ? 166.541 198.115 203.415 1.00 59.87  ? 95  PHE A CB  1 
ATOM 6567 C CG  . PHE E 4 83  ? 167.699 198.792 202.744 1.00 59.87  ? 95  PHE A CG  1 
ATOM 6568 C CD1 . PHE E 4 83  ? 168.045 200.085 203.086 1.00 59.87  ? 95  PHE A CD1 1 
ATOM 6569 C CD2 . PHE E 4 83  ? 168.436 198.144 201.772 1.00 59.87  ? 95  PHE A CD2 1 
ATOM 6570 C CE1 . PHE E 4 83  ? 169.105 200.717 202.475 1.00 59.87  ? 95  PHE A CE1 1 
ATOM 6571 C CE2 . PHE E 4 83  ? 169.497 198.772 201.156 1.00 59.87  ? 95  PHE A CE2 1 
ATOM 6572 C CZ  . PHE E 4 83  ? 169.832 200.060 201.509 1.00 59.87  ? 95  PHE A CZ  1 
ATOM 6573 N N   . LEU E 4 84  ? 165.262 197.396 200.590 1.00 57.40  ? 96  LEU A N   1 
ATOM 6574 C CA  . LEU E 4 84  ? 165.293 197.397 199.131 1.00 57.40  ? 96  LEU A CA  1 
ATOM 6575 C C   . LEU E 4 84  ? 164.057 198.078 198.559 1.00 57.40  ? 96  LEU A C   1 
ATOM 6576 O O   . LEU E 4 84  ? 164.137 198.810 197.566 1.00 57.40  ? 96  LEU A O   1 
ATOM 6577 C CB  . LEU E 4 84  ? 165.417 195.967 198.606 1.00 57.40  ? 96  LEU A CB  1 
ATOM 6578 C CG  . LEU E 4 84  ? 166.802 195.557 198.106 1.00 57.40  ? 96  LEU A CG  1 
ATOM 6579 C CD1 . LEU E 4 84  ? 167.842 195.756 199.188 1.00 57.40  ? 96  LEU A CD1 1 
ATOM 6580 C CD2 . LEU E 4 84  ? 166.791 194.116 197.635 1.00 57.40  ? 96  LEU A CD2 1 
ATOM 6581 N N   . LYS E 4 85  ? 162.900 197.857 199.180 1.00 63.71  ? 97  LYS A N   1 
ATOM 6582 C CA  . LYS E 4 85  ? 161.662 198.454 198.698 1.00 63.71  ? 97  LYS A CA  1 
ATOM 6583 C C   . LYS E 4 85  ? 161.549 199.901 199.159 1.00 63.71  ? 97  LYS A C   1 
ATOM 6584 O O   . LYS E 4 85  ? 160.543 200.567 198.895 1.00 63.71  ? 97  LYS A O   1 
ATOM 6585 C CB  . LYS E 4 85  ? 160.454 197.645 199.172 1.00 63.71  ? 97  LYS A CB  1 
ATOM 6586 C CG  . LYS E 4 85  ? 159.277 197.676 198.211 1.00 63.71  ? 97  LYS A CG  1 
ATOM 6587 C CD  . LYS E 4 85  ? 158.461 196.395 198.277 1.00 63.71  ? 97  LYS A CD  1 
ATOM 6588 C CE  . LYS E 4 85  ? 158.318 195.896 199.705 1.00 63.71  ? 97  LYS A CE  1 
ATOM 6589 N NZ  . LYS E 4 85  ? 157.003 195.238 199.931 1.00 63.71  ? 97  LYS A NZ  1 
ATOM 6590 N N   . ASN E 4 86  ? 162.575 200.398 199.848 1.00 61.34  ? 98  ASN A N   1 
ATOM 6591 C CA  . ASN E 4 86  ? 162.613 201.798 200.247 1.00 61.34  ? 98  ASN A CA  1 
ATOM 6592 C C   . ASN E 4 86  ? 163.616 202.550 199.387 1.00 61.34  ? 98  ASN A C   1 
ATOM 6593 O O   . ASN E 4 86  ? 163.451 203.746 199.131 1.00 61.34  ? 98  ASN A O   1 
ATOM 6594 C CB  . ASN E 4 86  ? 162.967 201.935 201.728 1.00 61.34  ? 98  ASN A CB  1 
ATOM 6595 C CG  . ASN E 4 86  ? 161.743 201.986 202.615 1.00 61.34  ? 98  ASN A CG  1 
ATOM 6596 O OD1 . ASN E 4 86  ? 160.679 201.484 202.253 1.00 61.34  ? 98  ASN A OD1 1 
ATOM 6597 N ND2 . ASN E 4 86  ? 161.884 202.599 203.783 1.00 61.34  ? 98  ASN A ND2 1 
ATOM 6598 N N   . TYR E 4 87  ? 164.656 201.862 198.941 1.00 56.84  ? 99  TYR A N   1 
ATOM 6599 C CA  . TYR E 4 87  ? 165.573 202.470 197.989 1.00 56.84  ? 99  TYR A CA  1 
ATOM 6600 C C   . TYR E 4 87  ? 165.057 202.380 196.567 1.00 56.84  ? 99  TYR A C   1 
ATOM 6601 O O   . TYR E 4 87  ? 165.614 202.988 195.647 1.00 56.84  ? 99  TYR A O   1 
ATOM 6602 C CB  . TYR E 4 87  ? 166.951 201.816 198.117 1.00 56.84  ? 99  TYR A CB  1 
ATOM 6603 C CG  . TYR E 4 87  ? 168.026 202.411 197.235 1.00 56.84  ? 99  TYR A CG  1 
ATOM 6604 C CD1 . TYR E 4 87  ? 168.741 203.527 197.642 1.00 56.84  ? 99  TYR A CD1 1 
ATOM 6605 C CD2 . TYR E 4 87  ? 168.321 201.862 195.995 1.00 56.84  ? 99  TYR A CD2 1 
ATOM 6606 C CE1 . TYR E 4 87  ? 169.721 204.076 196.842 1.00 56.84  ? 99  TYR A CE1 1 
ATOM 6607 C CE2 . TYR E 4 87  ? 169.299 202.403 195.189 1.00 56.84  ? 99  TYR A CE2 1 
ATOM 6608 C CZ  . TYR E 4 87  ? 169.996 203.509 195.617 1.00 56.84  ? 99  TYR A CZ  1 
ATOM 6609 O OH  . TYR E 4 87  ? 170.973 204.052 194.815 1.00 56.84  ? 99  TYR A OH  1 
ATOM 6610 N N   . LEU E 4 88  ? 163.961 201.645 196.364 1.00 58.82  ? 100 LEU A N   1 
ATOM 6611 C CA  . LEU E 4 88  ? 163.353 201.510 195.048 1.00 58.82  ? 100 LEU A CA  1 
ATOM 6612 C C   . LEU E 4 88  ? 162.023 202.246 194.943 1.00 58.82  ? 100 LEU A C   1 
ATOM 6613 O O   . LEU E 4 88  ? 161.449 202.310 193.850 1.00 58.82  ? 100 LEU A O   1 
ATOM 6614 C CB  . LEU E 4 88  ? 163.161 200.031 194.698 1.00 58.82  ? 100 LEU A CB  1 
ATOM 6615 C CG  . LEU E 4 88  ? 164.440 199.310 194.277 1.00 58.82  ? 100 LEU A CG  1 
ATOM 6616 C CD1 . LEU E 4 88  ? 164.120 198.065 193.480 1.00 58.82  ? 100 LEU A CD1 1 
ATOM 6617 C CD2 . LEU E 4 88  ? 165.338 200.242 193.484 1.00 58.82  ? 100 LEU A CD2 1 
ATOM 6618 N N   . THR E 4 89  ? 161.520 202.800 196.044 1.00 65.85  ? 101 THR A N   1 
ATOM 6619 C CA  . THR E 4 89  ? 160.296 203.589 196.042 1.00 65.85  ? 101 THR A CA  1 
ATOM 6620 C C   . THR E 4 89  ? 160.567 205.059 196.313 1.00 65.85  ? 101 THR A C   1 
ATOM 6621 O O   . THR E 4 89  ? 159.958 205.927 195.677 1.00 65.85  ? 101 THR A O   1 
ATOM 6622 C CB  . THR E 4 89  ? 159.305 203.032 197.078 1.00 65.85  ? 101 THR A CB  1 
ATOM 6623 O OG1 . THR E 4 89  ? 158.834 201.750 196.647 1.00 65.85  ? 101 THR A OG1 1 
ATOM 6624 C CG2 . THR E 4 89  ? 158.117 203.965 197.248 1.00 65.85  ? 101 THR A CG2 1 
ATOM 6625 N N   . ASN E 4 90  ? 161.486 205.366 197.229 1.00 67.93  ? 102 ASN A N   1 
ATOM 6626 C CA  . ASN E 4 90  ? 161.902 206.742 197.463 1.00 67.93  ? 102 ASN A CA  1 
ATOM 6627 C C   . ASN E 4 90  ? 162.675 207.243 196.251 1.00 67.93  ? 102 ASN A C   1 
ATOM 6628 O O   . ASN E 4 90  ? 162.824 208.452 196.049 1.00 67.93  ? 102 ASN A O   1 
ATOM 6629 C CB  . ASN E 4 90  ? 162.738 206.830 198.747 1.00 67.93  ? 102 ASN A CB  1 
ATOM 6630 C CG  . ASN E 4 90  ? 163.531 208.123 198.860 1.00 67.93  ? 102 ASN A CG  1 
ATOM 6631 O OD1 . ASN E 4 90  ? 164.532 208.321 198.169 1.00 67.93  ? 102 ASN A OD1 1 
ATOM 6632 N ND2 . ASN E 4 90  ? 163.083 209.012 199.738 1.00 67.93  ? 102 ASN A ND2 1 
ATOM 6633 N N   . LEU E 4 91  ? 163.134 206.315 195.415 1.00 61.82  ? 103 LEU A N   1 
ATOM 6634 C CA  . LEU E 4 91  ? 163.879 206.645 194.211 1.00 61.82  ? 103 LEU A CA  1 
ATOM 6635 C C   . LEU E 4 91  ? 163.000 206.782 192.979 1.00 61.82  ? 103 LEU A C   1 
ATOM 6636 O O   . LEU E 4 91  ? 163.362 207.511 192.054 1.00 61.82  ? 103 LEU A O   1 
ATOM 6637 C CB  . LEU E 4 91  ? 164.947 205.580 193.949 1.00 61.82  ? 103 LEU A CB  1 
ATOM 6638 C CG  . LEU E 4 91  ? 165.899 205.814 192.785 1.00 61.82  ? 103 LEU A CG  1 
ATOM 6639 C CD1 . LEU E 4 91  ? 166.938 206.839 193.197 1.00 61.82  ? 103 LEU A CD1 1 
ATOM 6640 C CD2 . LEU E 4 91  ? 166.544 204.503 192.380 1.00 61.82  ? 103 LEU A CD2 1 
ATOM 6641 N N   . LEU E 4 92  ? 161.851 206.107 192.953 1.00 71.38  ? 104 LEU A N   1 
ATOM 6642 C CA  . LEU E 4 92  ? 160.901 206.273 191.859 1.00 71.38  ? 104 LEU A CA  1 
ATOM 6643 C C   . LEU E 4 92  ? 160.376 207.703 191.808 1.00 71.38  ? 104 LEU A C   1 
ATOM 6644 O O   . LEU E 4 92  ? 159.991 208.203 190.746 1.00 71.38  ? 104 LEU A O   1 
ATOM 6645 C CB  . LEU E 4 92  ? 159.750 205.280 192.024 1.00 71.38  ? 104 LEU A CB  1 
ATOM 6646 C CG  . LEU E 4 92  ? 158.726 205.159 190.895 1.00 71.38  ? 104 LEU A CG  1 
ATOM 6647 C CD1 . LEU E 4 92  ? 159.377 205.320 189.532 1.00 71.38  ? 104 LEU A CD1 1 
ATOM 6648 C CD2 . LEU E 4 92  ? 158.007 203.832 190.996 1.00 71.38  ? 104 LEU A CD2 1 
ATOM 6649 N N   . LYS E 4 93  ? 160.350 208.372 192.962 1.00 75.18  ? 105 LYS A N   1 
ATOM 6650 C CA  . LYS E 4 93  ? 159.847 209.736 193.068 1.00 75.18  ? 105 LYS A CA  1 
ATOM 6651 C C   . LYS E 4 93  ? 160.587 210.661 192.111 1.00 75.18  ? 105 LYS A C   1 
ATOM 6652 O O   . LYS E 4 93  ? 159.973 211.512 191.461 1.00 75.18  ? 105 LYS A O   1 
ATOM 6653 C CB  . LYS E 4 93  ? 159.978 210.240 194.507 1.00 75.18  ? 105 LYS A CB  1 
ATOM 6654 C CG  . LYS E 4 93  ? 158.852 211.157 194.949 1.00 75.18  ? 105 LYS A CG  1 
ATOM 6655 C CD  . LYS E 4 93  ? 159.090 211.681 196.356 1.00 75.18  ? 105 LYS A CD  1 
ATOM 6656 C CE  . LYS E 4 93  ? 158.732 210.640 197.402 1.00 75.18  ? 105 LYS A CE  1 
ATOM 6657 N NZ  . LYS E 4 93  ? 157.320 210.189 197.274 1.00 75.18  ? 105 LYS A NZ  1 
ATOM 6658 N N   . ASP E 4 94  ? 161.904 210.502 192.021 1.00 78.37  ? 106 ASP A N   1 
ATOM 6659 C CA  . ASP E 4 94  ? 162.722 211.230 191.052 1.00 78.37  ? 106 ASP A CA  1 
ATOM 6660 C C   . ASP E 4 94  ? 162.845 210.352 189.811 1.00 78.37  ? 106 ASP A C   1 
ATOM 6661 O O   . ASP E 4 94  ? 163.556 209.348 189.807 1.00 78.37  ? 106 ASP A O   1 
ATOM 6662 C CB  . ASP E 4 94  ? 164.085 211.575 191.640 1.00 78.37  ? 106 ASP A CB  1 
ATOM 6663 C CG  . ASP E 4 94  ? 165.074 212.039 190.589 1.00 78.37  ? 106 ASP A CG  1 
ATOM 6664 O OD1 . ASP E 4 94  ? 164.656 212.736 189.641 1.00 78.37  ? 106 ASP A OD1 1 
ATOM 6665 O OD2 . ASP E 4 94  ? 166.271 211.703 190.708 1.00 78.37  ? 106 ASP A OD2 1 
ATOM 6666 N N   . GLY E 4 95  ? 162.142 210.735 188.748 1.00 87.03  ? 107 GLY A N   1 
ATOM 6667 C CA  . GLY E 4 95  ? 162.205 209.983 187.510 1.00 87.03  ? 107 GLY A CA  1 
ATOM 6668 C C   . GLY E 4 95  ? 160.863 209.751 186.847 1.00 87.03  ? 107 GLY A C   1 
ATOM 6669 O O   . GLY E 4 95  ? 160.786 209.629 185.622 1.00 87.03  ? 107 GLY A O   1 
ATOM 6670 N N   . GLU E 4 96  ? 159.793 209.706 187.639 1.00 93.58  ? 108 GLU A N   1 
ATOM 6671 C CA  . GLU E 4 96  ? 158.476 209.388 187.102 1.00 93.58  ? 108 GLU A CA  1 
ATOM 6672 C C   . GLU E 4 96  ? 157.725 210.656 186.711 1.00 93.58  ? 108 GLU A C   1 
ATOM 6673 O O   . GLU E 4 96  ? 156.492 210.671 186.640 1.00 93.58  ? 108 GLU A O   1 
ATOM 6674 C CB  . GLU E 4 96  ? 157.682 208.563 188.118 1.00 93.58  ? 108 GLU A CB  1 
ATOM 6675 C CG  . GLU E 4 96  ? 157.098 209.365 189.272 1.00 93.58  ? 108 GLU A CG  1 
ATOM 6676 C CD  . GLU E 4 96  ? 155.860 208.723 189.858 1.00 93.58  ? 108 GLU A CD  1 
ATOM 6677 O OE1 . GLU E 4 96  ? 155.523 209.031 191.020 1.00 93.58  ? 108 GLU A OE1 1 
ATOM 6678 O OE2 . GLU E 4 96  ? 155.215 207.920 189.152 1.00 93.58  ? 108 GLU A OE2 1 
ATOM 6679 N N   . ASP E 4 97  ? 158.474 211.711 186.409 1.00 96.16  ? 109 ASP A N   1 
ATOM 6680 C CA  . ASP E 4 97  ? 157.908 212.965 185.931 1.00 96.16  ? 109 ASP A CA  1 
ATOM 6681 C C   . ASP E 4 97  ? 158.724 213.454 184.742 1.00 96.16  ? 109 ASP A C   1 
ATOM 6682 O O   . ASP E 4 97  ? 158.694 214.637 184.387 1.00 96.16  ? 109 ASP A O   1 
ATOM 6683 C CB  . ASP E 4 97  ? 157.858 214.000 187.062 1.00 96.16  ? 109 ASP A CB  1 
ATOM 6684 C CG  . ASP E 4 97  ? 159.231 214.556 187.430 1.00 96.16  ? 109 ASP A CG  1 
ATOM 6685 O OD1 . ASP E 4 97  ? 160.263 213.997 187.002 1.00 96.16  ? 109 ASP A OD1 1 
ATOM 6686 O OD2 . ASP E 4 97  ? 159.275 215.562 188.168 1.00 96.16  ? 109 ASP A OD2 1 
ATOM 6687 N N   . LEU E 4 98  ? 159.458 212.531 184.128 1.00 91.48  ? 110 LEU A N   1 
ATOM 6688 C CA  . LEU E 4 98  ? 160.492 212.839 183.153 1.00 91.48  ? 110 LEU A CA  1 
ATOM 6689 C C   . LEU E 4 98  ? 160.068 212.320 181.786 1.00 91.48  ? 110 LEU A C   1 
ATOM 6690 O O   . LEU E 4 98  ? 159.452 211.255 181.687 1.00 91.48  ? 110 LEU A O   1 
ATOM 6691 C CB  . LEU E 4 98  ? 161.817 212.215 183.590 1.00 91.48  ? 110 LEU A CB  1 
ATOM 6692 C CG  . LEU E 4 98  ? 162.657 213.073 184.536 1.00 91.48  ? 110 LEU A CG  1 
ATOM 6693 C CD1 . LEU E 4 98  ? 163.970 212.388 184.870 1.00 91.48  ? 110 LEU A CD1 1 
ATOM 6694 C CD2 . LEU E 4 98  ? 162.902 214.446 183.932 1.00 91.48  ? 110 LEU A CD2 1 
ATOM 6695 N N   . MET E 4 99  ? 160.381 213.083 180.742 1.00 96.93  ? 111 MET A N   1 
ATOM 6696 C CA  . MET E 4 99  ? 160.010 212.736 179.380 1.00 96.93  ? 111 MET A CA  1 
ATOM 6697 C C   . MET E 4 99  ? 161.194 212.000 178.739 1.00 96.93  ? 111 MET A C   1 
ATOM 6698 O O   . MET E 4 99  ? 162.145 211.613 179.423 1.00 96.93  ? 111 MET A O   1 
ATOM 6699 C CB  . MET E 4 99  ? 159.563 214.011 178.653 1.00 96.93  ? 111 MET A CB  1 
ATOM 6700 C CG  . MET E 4 99  ? 159.085 213.870 177.209 1.00 96.93  ? 111 MET A CG  1 
ATOM 6701 S SD  . MET E 4 99  ? 157.967 215.201 176.727 1.00 96.93  ? 111 MET A SD  1 
ATOM 6702 C CE  . MET E 4 99  ? 156.987 214.385 175.470 1.00 96.93  ? 111 MET A CE  1 
ATOM 6703 N N   . ASP E 4 100 ? 161.150 211.786 177.422 1.00 91.96  ? 112 ASP A N   1 
ATOM 6704 C CA  . ASP E 4 100 ? 162.174 211.041 176.697 1.00 91.96  ? 112 ASP A CA  1 
ATOM 6705 C C   . ASP E 4 100 ? 163.573 211.621 176.879 1.00 91.96  ? 112 ASP A C   1 
ATOM 6706 O O   . ASP E 4 100 ? 163.726 212.768 177.311 1.00 91.96  ? 112 ASP A O   1 
ATOM 6707 C CB  . ASP E 4 100 ? 161.788 210.950 175.208 1.00 91.96  ? 112 ASP A CB  1 
ATOM 6708 C CG  . ASP E 4 100 ? 162.061 212.239 174.412 1.00 91.96  ? 112 ASP A CG  1 
ATOM 6709 O OD1 . ASP E 4 100 ? 163.109 212.897 174.573 1.00 91.96  ? 112 ASP A OD1 1 
ATOM 6710 O OD2 . ASP E 4 100 ? 161.188 212.601 173.595 1.00 91.96  ? 112 ASP A OD2 1 
ATOM 6711 N N   . GLU E 4 101 ? 164.593 210.818 176.567 1.00 82.04  ? 113 GLU A N   1 
ATOM 6712 C CA  . GLU E 4 101 ? 165.996 211.220 176.635 1.00 82.04  ? 113 GLU A CA  1 
ATOM 6713 C C   . GLU E 4 101 ? 166.418 211.615 178.045 1.00 82.04  ? 113 GLU A C   1 
ATOM 6714 O O   . GLU E 4 101 ? 167.521 212.135 178.245 1.00 82.04  ? 113 GLU A O   1 
ATOM 6715 C CB  . GLU E 4 101 ? 166.276 212.369 175.661 1.00 82.04  ? 113 GLU A CB  1 
ATOM 6716 C CG  . GLU E 4 101 ? 167.022 211.950 174.406 1.00 82.04  ? 113 GLU A CG  1 
ATOM 6717 C CD  . GLU E 4 101 ? 167.990 210.810 174.654 1.00 82.04  ? 113 GLU A CD  1 
ATOM 6718 O OE1 . GLU E 4 101 ? 168.957 211.005 175.422 1.00 82.04  ? 113 GLU A OE1 1 
ATOM 6719 O OE2 . GLU E 4 101 ? 167.786 209.719 174.082 1.00 82.04  ? 113 GLU A OE2 1 
ATOM 6720 N N   . SER E 4 102 ? 165.554 211.374 179.028 1.00 78.63  ? 114 SER A N   1 
ATOM 6721 C CA  . SER E 4 102 ? 165.902 211.624 180.419 1.00 78.63  ? 114 SER A CA  1 
ATOM 6722 C C   . SER E 4 102 ? 165.602 210.385 181.250 1.00 78.63  ? 114 SER A C   1 
ATOM 6723 O O   . SER E 4 102 ? 166.340 210.062 182.186 1.00 78.63  ? 114 SER A O   1 
ATOM 6724 C CB  . SER E 4 102 ? 165.149 212.842 180.952 1.00 78.63  ? 114 SER A CB  1 
ATOM 6725 O OG  . SER E 4 102 ? 165.488 213.090 182.302 1.00 78.63  ? 114 SER A OG  1 
ATOM 6726 N N   . VAL E 4 103 ? 164.523 209.680 180.911 1.00 70.62  ? 115 VAL A N   1 
ATOM 6727 C CA  . VAL E 4 103 ? 164.225 208.395 181.529 1.00 70.62  ? 115 VAL A CA  1 
ATOM 6728 C C   . VAL E 4 103 ? 165.099 207.344 180.866 1.00 70.62  ? 115 VAL A C   1 
ATOM 6729 O O   . VAL E 4 103 ? 165.174 206.199 181.324 1.00 70.62  ? 115 VAL A O   1 
ATOM 6730 C CB  . VAL E 4 103 ? 162.735 208.031 181.407 1.00 70.62  ? 115 VAL A CB  1 
ATOM 6731 C CG1 . VAL E 4 103 ? 161.876 209.226 181.727 1.00 70.62  ? 115 VAL A CG1 1 
ATOM 6732 C CG2 . VAL E 4 103 ? 162.427 207.528 180.012 1.00 70.62  ? 115 VAL A CG2 1 
ATOM 6733 N N   . LEU E 4 104 ? 165.767 207.730 179.779 1.00 67.33  ? 116 LEU A N   1 
ATOM 6734 C CA  . LEU E 4 104 ? 166.716 206.851 179.115 1.00 67.33  ? 116 LEU A CA  1 
ATOM 6735 C C   . LEU E 4 104 ? 168.140 207.165 179.554 1.00 67.33  ? 116 LEU A C   1 
ATOM 6736 O O   . LEU E 4 104 ? 169.095 206.554 179.067 1.00 67.33  ? 116 LEU A O   1 
ATOM 6737 C CB  . LEU E 4 104 ? 166.589 206.955 177.596 1.00 67.33  ? 116 LEU A CB  1 
ATOM 6738 C CG  . LEU E 4 104 ? 167.214 205.810 176.803 1.00 67.33  ? 116 LEU A CG  1 
ATOM 6739 C CD1 . LEU E 4 104 ? 166.208 204.700 176.630 1.00 67.33  ? 116 LEU A CD1 1 
ATOM 6740 C CD2 . LEU E 4 104 ? 167.713 206.305 175.462 1.00 67.33  ? 116 LEU A CD2 1 
ATOM 6741 N N   . LYS E 4 105 ? 168.299 208.116 180.467 1.00 65.97  ? 117 LYS A N   1 
ATOM 6742 C CA  . LYS E 4 105 ? 169.585 208.361 181.106 1.00 65.97  ? 117 LYS A CA  1 
ATOM 6743 C C   . LYS E 4 105 ? 169.397 208.221 182.614 1.00 65.97  ? 117 LYS A C   1 
ATOM 6744 O O   . LYS E 4 105 ? 170.166 208.747 183.419 1.00 65.97  ? 117 LYS A O   1 
ATOM 6745 C CB  . LYS E 4 105 ? 170.144 209.730 180.718 1.00 65.97  ? 117 LYS A CB  1 
ATOM 6746 C CG  . LYS E 4 105 ? 171.646 209.863 180.913 1.00 65.97  ? 117 LYS A CG  1 
ATOM 6747 C CD  . LYS E 4 105 ? 172.300 210.556 179.730 1.00 65.97  ? 117 LYS A CD  1 
ATOM 6748 C CE  . LYS E 4 105 ? 171.725 211.944 179.511 1.00 65.97  ? 117 LYS A CE  1 
ATOM 6749 N NZ  . LYS E 4 105 ? 172.588 212.761 178.614 1.00 65.97  ? 117 LYS A NZ  1 
ATOM 6750 N N   . PHE E 4 106 ? 168.347 207.500 183.002 1.00 67.69  ? 118 PHE A N   1 
ATOM 6751 C CA  . PHE E 4 106 ? 168.035 207.247 184.401 1.00 67.69  ? 118 PHE A CA  1 
ATOM 6752 C C   . PHE E 4 106 ? 167.902 205.749 184.639 1.00 67.69  ? 118 PHE A C   1 
ATOM 6753 O O   . PHE E 4 106 ? 168.164 205.262 185.743 1.00 67.69  ? 118 PHE A O   1 
ATOM 6754 C CB  . PHE E 4 106 ? 166.754 207.979 184.799 1.00 67.69  ? 118 PHE A CB  1 
ATOM 6755 C CG  . PHE E 4 106 ? 166.288 207.673 186.187 1.00 67.69  ? 118 PHE A CG  1 
ATOM 6756 C CD1 . PHE E 4 106 ? 166.809 208.353 187.270 1.00 67.69  ? 118 PHE A CD1 1 
ATOM 6757 C CD2 . PHE E 4 106 ? 165.328 206.702 186.409 1.00 67.69  ? 118 PHE A CD2 1 
ATOM 6758 C CE1 . PHE E 4 106 ? 166.380 208.071 188.548 1.00 67.69  ? 118 PHE A CE1 1 
ATOM 6759 C CE2 . PHE E 4 106 ? 164.895 206.416 187.683 1.00 67.69  ? 118 PHE A CE2 1 
ATOM 6760 C CZ  . PHE E 4 106 ? 165.422 207.100 188.755 1.00 67.69  ? 118 PHE A CZ  1 
ATOM 6761 N N   . TYR E 4 107 ? 167.490 205.014 183.609 1.00 76.28  ? 119 TYR A N   1 
ATOM 6762 C CA  . TYR E 4 107 ? 167.367 203.567 183.707 1.00 76.28  ? 119 TYR A CA  1 
ATOM 6763 C C   . TYR E 4 107 ? 168.518 202.910 182.956 1.00 76.28  ? 119 TYR A C   1 
ATOM 6764 O O   . TYR E 4 107 ? 168.413 201.767 182.503 1.00 76.28  ? 119 TYR A O   1 
ATOM 6765 C CB  . TYR E 4 107 ? 166.001 203.117 183.179 1.00 76.28  ? 119 TYR A CB  1 
ATOM 6766 C CG  . TYR E 4 107 ? 165.733 201.634 183.289 1.00 76.28  ? 119 TYR A CG  1 
ATOM 6767 C CD1 . TYR E 4 107 ? 165.706 201.005 184.519 1.00 76.28  ? 119 TYR A CD1 1 
ATOM 6768 C CD2 . TYR E 4 107 ? 165.537 200.861 182.157 1.00 76.28  ? 119 TYR A CD2 1 
ATOM 6769 C CE1 . TYR E 4 107 ? 165.473 199.651 184.619 1.00 76.28  ? 119 TYR A CE1 1 
ATOM 6770 C CE2 . TYR E 4 107 ? 165.300 199.509 182.250 1.00 76.28  ? 119 TYR A CE2 1 
ATOM 6771 C CZ  . TYR E 4 107 ? 165.269 198.910 183.482 1.00 76.28  ? 119 TYR A CZ  1 
ATOM 6772 O OH  . TYR E 4 107 ? 165.037 197.560 183.579 1.00 76.28  ? 119 TYR A OH  1 
ATOM 6773 N N   . THR E 4 108 ? 169.629 203.628 182.818 1.00 62.48  ? 120 THR A N   1 
ATOM 6774 C CA  . THR E 4 108 ? 170.849 203.028 182.297 1.00 62.48  ? 120 THR A CA  1 
ATOM 6775 C C   . THR E 4 108 ? 172.009 203.370 183.218 1.00 62.48  ? 120 THR A C   1 
ATOM 6776 O O   . THR E 4 108 ? 173.052 202.709 183.193 1.00 62.48  ? 120 THR A O   1 
ATOM 6777 C CB  . THR E 4 108 ? 171.153 203.515 180.884 1.00 62.48  ? 120 THR A CB  1 
ATOM 6778 O OG1 . THR E 4 108 ? 172.491 203.142 180.535 1.00 62.48  ? 120 THR A OG1 1 
ATOM 6779 C CG2 . THR E 4 108 ? 171.059 205.019 180.835 1.00 62.48  ? 120 THR A CG2 1 
ATOM 6780 N N   . GLN E 4 109 ? 171.833 204.410 184.031 1.00 53.85  ? 121 GLN A N   1 
ATOM 6781 C CA  . GLN E 4 109 ? 172.830 204.812 185.014 1.00 53.85  ? 121 GLN A CA  1 
ATOM 6782 C C   . GLN E 4 109 ? 172.496 204.206 186.376 1.00 53.85  ? 121 GLN A C   1 
ATOM 6783 O O   . GLN E 4 109 ? 173.367 203.614 187.015 1.00 53.85  ? 121 GLN A O   1 
ATOM 6784 C CB  . GLN E 4 109 ? 172.927 206.334 185.099 1.00 53.85  ? 121 GLN A CB  1 
ATOM 6785 C CG  . GLN E 4 109 ? 173.881 206.824 186.168 1.00 53.85  ? 121 GLN A CG  1 
ATOM 6786 C CD  . GLN E 4 109 ? 175.184 207.332 185.590 1.00 53.85  ? 121 GLN A CD  1 
ATOM 6787 O OE1 . GLN E 4 109 ? 175.191 208.131 184.654 1.00 53.85  ? 121 GLN A OE1 1 
ATOM 6788 N NE2 . GLN E 4 109 ? 176.298 206.865 186.141 1.00 53.85  ? 121 GLN A NE2 1 
ATOM 6789 N N   . GLN E 4 110 ? 171.255 204.340 186.835 1.00 49.45  ? 122 GLN A N   1 
ATOM 6790 C CA  . GLN E 4 110 ? 170.859 203.715 188.090 1.00 49.45  ? 122 GLN A CA  1 
ATOM 6791 C C   . GLN E 4 110 ? 170.282 202.332 187.827 1.00 49.45  ? 122 GLN A C   1 
ATOM 6792 O O   . GLN E 4 110 ? 169.215 201.974 188.335 1.00 49.45  ? 122 GLN A O   1 
ATOM 6793 C CB  . GLN E 4 110 ? 169.867 204.607 188.827 1.00 49.45  ? 122 GLN A CB  1 
ATOM 6794 C CG  . GLN E 4 110 ? 170.496 205.908 189.278 1.00 49.45  ? 122 GLN A CG  1 
ATOM 6795 C CD  . GLN E 4 110 ? 169.679 206.606 190.327 1.00 49.45  ? 122 GLN A CD  1 
ATOM 6796 O OE1 . GLN E 4 110 ? 168.649 206.098 190.752 1.00 49.45  ? 122 GLN A OE1 1 
ATOM 6797 N NE2 . GLN E 4 110 ? 170.136 207.773 190.761 1.00 49.45  ? 122 GLN A NE2 1 
ATOM 6798 N N   . TRP E 4 111 ? 171.003 201.557 187.022 1.00 50.88  ? 123 TRP A N   1 
ATOM 6799 C CA  . TRP E 4 111 ? 170.790 200.130 186.846 1.00 50.88  ? 123 TRP A CA  1 
ATOM 6800 C C   . TRP E 4 111 ? 172.137 199.465 187.064 1.00 50.88  ? 123 TRP A C   1 
ATOM 6801 O O   . TRP E 4 111 ? 172.220 198.344 187.575 1.00 50.88  ? 123 TRP A O   1 
ATOM 6802 C CB  . TRP E 4 111 ? 170.233 199.821 185.458 1.00 50.88  ? 123 TRP A CB  1 
ATOM 6803 C CG  . TRP E 4 111 ? 170.272 198.370 185.067 1.00 50.88  ? 123 TRP A CG  1 
ATOM 6804 C CD1 . TRP E 4 111 ? 170.738 197.861 183.893 1.00 50.88  ? 123 TRP A CD1 1 
ATOM 6805 C CD2 . TRP E 4 111 ? 169.792 197.251 185.824 1.00 50.88  ? 123 TRP A CD2 1 
ATOM 6806 N NE1 . TRP E 4 111 ? 170.601 196.498 183.878 1.00 50.88  ? 123 TRP A NE1 1 
ATOM 6807 C CE2 . TRP E 4 111 ? 170.021 196.097 185.051 1.00 50.88  ? 123 TRP A CE2 1 
ATOM 6808 C CE3 . TRP E 4 111 ? 169.199 197.110 187.080 1.00 50.88  ? 123 TRP A CE3 1 
ATOM 6809 C CZ2 . TRP E 4 111 ? 169.681 194.824 185.493 1.00 50.88  ? 123 TRP A CZ2 1 
ATOM 6810 C CZ3 . TRP E 4 111 ? 168.863 195.843 187.516 1.00 50.88  ? 123 TRP A CZ3 1 
ATOM 6811 C CH2 . TRP E 4 111 ? 169.104 194.718 186.725 1.00 50.88  ? 123 TRP A CH2 1 
ATOM 6812 N N   . GLU E 4 112 ? 173.199 200.167 186.671 1.00 58.21  ? 124 GLU A N   1 
ATOM 6813 C CA  . GLU E 4 112 ? 174.563 199.745 186.955 1.00 58.21  ? 124 GLU A CA  1 
ATOM 6814 C C   . GLU E 4 112 ? 174.932 200.105 188.388 1.00 58.21  ? 124 GLU A C   1 
ATOM 6815 O O   . GLU E 4 112 ? 175.948 199.638 188.910 1.00 58.21  ? 124 GLU A O   1 
ATOM 6816 C CB  . GLU E 4 112 ? 175.541 200.387 185.971 1.00 58.21  ? 124 GLU A CB  1 
ATOM 6817 C CG  . GLU E 4 112 ? 175.661 199.650 184.648 1.00 58.21  ? 124 GLU A CG  1 
ATOM 6818 C CD  . GLU E 4 112 ? 176.207 198.244 184.804 1.00 58.21  ? 124 GLU A CD  1 
ATOM 6819 O OE1 . GLU E 4 112 ? 176.979 198.004 185.756 1.00 58.21  ? 124 GLU A OE1 1 
ATOM 6820 O OE2 . GLU E 4 112 ? 175.866 197.377 183.972 1.00 58.21  ? 124 GLU A OE2 1 
ATOM 6821 N N   . ASP E 4 113 ? 174.117 200.942 189.027 1.00 55.12  ? 125 ASP A N   1 
ATOM 6822 C CA  . ASP E 4 113 ? 174.292 201.280 190.436 1.00 55.12  ? 125 ASP A CA  1 
ATOM 6823 C C   . ASP E 4 113 ? 173.319 200.482 191.288 1.00 55.12  ? 125 ASP A C   1 
ATOM 6824 O O   . ASP E 4 113 ? 173.125 200.765 192.474 1.00 55.12  ? 125 ASP A O   1 
ATOM 6825 C CB  . ASP E 4 113 ? 174.123 202.778 190.677 1.00 55.12  ? 125 ASP A CB  1 
ATOM 6826 C CG  . ASP E 4 113 ? 175.398 203.553 190.424 1.00 55.12  ? 125 ASP A CG  1 
ATOM 6827 O OD1 . ASP E 4 113 ? 176.130 203.201 189.476 1.00 55.12  ? 125 ASP A OD1 1 
ATOM 6828 O OD2 . ASP E 4 113 ? 175.671 204.513 191.174 1.00 55.12  ? 125 ASP A OD2 1 
ATOM 6829 N N   . TYR E 4 114 ? 172.676 199.479 190.682 1.00 45.04  ? 126 TYR A N   1 
ATOM 6830 C CA  . TYR E 4 114 ? 171.894 198.528 191.463 1.00 45.04  ? 126 TYR A CA  1 
ATOM 6831 C C   . TYR E 4 114 ? 172.282 197.093 191.125 1.00 45.04  ? 126 TYR A C   1 
ATOM 6832 O O   . TYR E 4 114 ? 172.233 196.232 192.011 1.00 45.04  ? 126 TYR A O   1 
ATOM 6833 C CB  . TYR E 4 114 ? 170.388 198.772 191.240 1.00 45.04  ? 126 TYR A CB  1 
ATOM 6834 C CG  . TYR E 4 114 ? 169.453 197.907 192.060 1.00 45.04  ? 126 TYR A CG  1 
ATOM 6835 C CD1 . TYR E 4 114 ? 169.278 196.561 191.770 1.00 45.04  ? 126 TYR A CD1 1 
ATOM 6836 C CD2 . TYR E 4 114 ? 168.699 198.453 193.086 1.00 45.04  ? 126 TYR A CD2 1 
ATOM 6837 C CE1 . TYR E 4 114 ? 168.421 195.777 192.506 1.00 45.04  ? 126 TYR A CE1 1 
ATOM 6838 C CE2 . TYR E 4 114 ? 167.836 197.675 193.827 1.00 45.04  ? 126 TYR A CE2 1 
ATOM 6839 C CZ  . TYR E 4 114 ? 167.700 196.337 193.530 1.00 45.04  ? 126 TYR A CZ  1 
ATOM 6840 O OH  . TYR E 4 114 ? 166.839 195.553 194.261 1.00 45.04  ? 126 TYR A OH  1 
ATOM 6841 N N   . ARG E 4 115 ? 172.693 196.812 189.892 1.00 52.84  ? 127 ARG A N   1 
ATOM 6842 C CA  . ARG E 4 115 ? 173.266 195.520 189.548 1.00 52.84  ? 127 ARG A CA  1 
ATOM 6843 C C   . ARG E 4 115 ? 174.621 195.311 190.202 1.00 52.84  ? 127 ARG A C   1 
ATOM 6844 O O   . ARG E 4 115 ? 174.877 194.251 190.781 1.00 52.84  ? 127 ARG A O   1 
ATOM 6845 C CB  . ARG E 4 115 ? 173.399 195.384 188.027 1.00 52.84  ? 127 ARG A CB  1 
ATOM 6846 C CG  . ARG E 4 115 ? 174.091 194.114 187.584 1.00 52.84  ? 127 ARG A CG  1 
ATOM 6847 C CD  . ARG E 4 115 ? 173.975 193.922 186.086 1.00 52.84  ? 127 ARG A CD  1 
ATOM 6848 N NE  . ARG E 4 115 ? 174.797 192.813 185.622 1.00 52.84  ? 127 ARG A NE  1 
ATOM 6849 C CZ  . ARG E 4 115 ? 174.315 191.656 185.192 1.00 52.84  ? 127 ARG A CZ  1 
ATOM 6850 N NH1 . ARG E 4 115 ? 173.015 191.424 185.146 1.00 52.84  ? 127 ARG A NH1 1 
ATOM 6851 N NH2 . ARG E 4 115 ? 175.160 190.707 184.800 1.00 52.84  ? 127 ARG A NH2 1 
ATOM 6852 N N   . PHE E 4 116 ? 175.497 196.310 190.123 1.00 56.21  ? 128 PHE A N   1 
ATOM 6853 C CA  . PHE E 4 116 ? 176.769 196.274 190.829 1.00 56.21  ? 128 PHE A CA  1 
ATOM 6854 C C   . PHE E 4 116 ? 176.561 196.336 192.334 1.00 56.21  ? 128 PHE A C   1 
ATOM 6855 O O   . PHE E 4 116 ? 177.138 195.540 193.081 1.00 56.21  ? 128 PHE A O   1 
ATOM 6856 C CB  . PHE E 4 116 ? 177.662 197.431 190.388 1.00 56.21  ? 128 PHE A CB  1 
ATOM 6857 C CG  . PHE E 4 116 ? 179.014 197.425 191.027 1.00 56.21  ? 128 PHE A CG  1 
ATOM 6858 C CD1 . PHE E 4 116 ? 179.754 196.260 191.099 1.00 56.21  ? 128 PHE A CD1 1 
ATOM 6859 C CD2 . PHE E 4 116 ? 179.536 198.582 191.577 1.00 56.21  ? 128 PHE A CD2 1 
ATOM 6860 C CE1 . PHE E 4 116 ? 180.997 196.253 191.692 1.00 56.21  ? 128 PHE A CE1 1 
ATOM 6861 C CE2 . PHE E 4 116 ? 180.777 198.581 192.173 1.00 56.21  ? 128 PHE A CE2 1 
ATOM 6862 C CZ  . PHE E 4 116 ? 181.509 197.416 192.231 1.00 56.21  ? 128 PHE A CZ  1 
ATOM 6863 N N   . SER E 4 117 ? 175.740 197.282 192.783 1.00 55.37  ? 129 SER A N   1 
ATOM 6864 C CA  . SER E 4 117 ? 175.563 197.515 194.209 1.00 55.37  ? 129 SER A CA  1 
ATOM 6865 C C   . SER E 4 117 ? 174.942 196.311 194.898 1.00 55.37  ? 129 SER A C   1 
ATOM 6866 O O   . SER E 4 117 ? 175.424 195.879 195.950 1.00 55.37  ? 129 SER A O   1 
ATOM 6867 C CB  . SER E 4 117 ? 174.710 198.756 194.445 1.00 55.37  ? 129 SER A CB  1 
ATOM 6868 O OG  . SER E 4 117 ? 174.929 199.253 195.748 1.00 55.37  ? 129 SER A OG  1 
ATOM 6869 N N   . SER E 4 118 ? 173.875 195.759 194.328 1.00 51.79  ? 130 SER A N   1 
ATOM 6870 C CA  . SER E 4 118 ? 173.309 194.527 194.868 1.00 51.79  ? 130 SER A CA  1 
ATOM 6871 C C   . SER E 4 118 ? 173.963 193.288 194.282 1.00 51.79  ? 130 SER A C   1 
ATOM 6872 O O   . SER E 4 118 ? 173.285 192.354 193.853 1.00 51.79  ? 130 SER A O   1 
ATOM 6873 C CB  . SER E 4 118 ? 171.801 194.500 194.640 1.00 51.79  ? 130 SER A CB  1 
ATOM 6874 O OG  . SER E 4 118 ? 171.199 193.516 195.456 1.00 51.79  ? 130 SER A OG  1 
ATOM 6875 N N   . LYS E 4 119 ? 175.294 193.270 194.266 1.00 51.85  ? 131 LYS A N   1 
ATOM 6876 C CA  . LYS E 4 119 ? 176.070 192.063 194.025 1.00 51.85  ? 131 LYS A CA  1 
ATOM 6877 C C   . LYS E 4 119 ? 177.146 191.939 195.094 1.00 51.85  ? 131 LYS A C   1 
ATOM 6878 O O   . LYS E 4 119 ? 177.787 190.888 195.210 1.00 51.85  ? 131 LYS A O   1 
ATOM 6879 C CB  . LYS E 4 119 ? 176.691 192.071 192.627 1.00 51.85  ? 131 LYS A CB  1 
ATOM 6880 C CG  . LYS E 4 119 ? 177.123 190.706 192.126 1.00 51.85  ? 131 LYS A CG  1 
ATOM 6881 C CD  . LYS E 4 119 ? 177.249 190.698 190.615 1.00 51.85  ? 131 LYS A CD  1 
ATOM 6882 C CE  . LYS E 4 119 ? 178.376 191.605 190.157 1.00 51.85  ? 131 LYS A CE  1 
ATOM 6883 N NZ  . LYS E 4 119 ? 178.502 191.631 188.675 1.00 51.85  ? 131 LYS A NZ  1 
ATOM 6884 N N   . VAL E 4 120 ? 177.346 192.998 195.874 1.00 52.35  ? 132 VAL A N   1 
ATOM 6885 C CA  . VAL E 4 120 ? 178.138 192.968 197.093 1.00 52.35  ? 132 VAL A CA  1 
ATOM 6886 C C   . VAL E 4 120 ? 177.201 192.472 198.185 1.00 52.35  ? 132 VAL A C   1 
ATOM 6887 O O   . VAL E 4 120 ? 177.629 191.866 199.174 1.00 52.35  ? 132 VAL A O   1 
ATOM 6888 C CB  . VAL E 4 120 ? 178.721 194.359 197.404 1.00 52.35  ? 132 VAL A CB  1 
ATOM 6889 C CG1 . VAL E 4 120 ? 179.180 194.458 198.843 1.00 52.35  ? 132 VAL A CG1 1 
ATOM 6890 C CG2 . VAL E 4 120 ? 179.864 194.675 196.455 1.00 52.35  ? 132 VAL A CG2 1 
ATOM 6891 N N   . LEU E 4 121 ? 175.903 192.693 197.979 1.00 53.32  ? 133 LEU A N   1 
ATOM 6892 C CA  . LEU E 4 121 ? 174.856 192.204 198.868 1.00 53.32  ? 133 LEU A CA  1 
ATOM 6893 C C   . LEU E 4 121 ? 174.621 190.713 198.655 1.00 53.32  ? 133 LEU A C   1 
ATOM 6894 O O   . LEU E 4 121 ? 173.667 190.139 199.187 1.00 53.32  ? 133 LEU A O   1 
ATOM 6895 C CB  . LEU E 4 121 ? 173.566 192.988 198.631 1.00 53.32  ? 133 LEU A CB  1 
ATOM 6896 C CG  . LEU E 4 121 ? 172.518 192.938 199.735 1.00 53.32  ? 133 LEU A CG  1 
ATOM 6897 C CD1 . LEU E 4 121 ? 173.056 193.699 200.901 1.00 53.32  ? 133 LEU A CD1 1 
ATOM 6898 C CD2 . LEU E 4 121 ? 171.210 193.534 199.263 1.00 53.32  ? 133 LEU A CD2 1 
ATOM 6899 N N   . ASN E 4 122 ? 175.497 190.076 197.886 1.00 51.14  ? 134 ASN A N   1 
ATOM 6900 C CA  . ASN E 4 122 ? 175.366 188.668 197.541 1.00 51.14  ? 134 ASN A CA  1 
ATOM 6901 C C   . ASN E 4 122 ? 176.649 187.963 197.956 1.00 51.14  ? 134 ASN A C   1 
ATOM 6902 O O   . ASN E 4 122 ? 177.328 187.339 197.135 1.00 51.14  ? 134 ASN A O   1 
ATOM 6903 C CB  . ASN E 4 122 ? 175.074 188.480 196.053 1.00 51.14  ? 134 ASN A CB  1 
ATOM 6904 C CG  . ASN E 4 122 ? 174.924 187.021 195.671 1.00 51.14  ? 134 ASN A CG  1 
ATOM 6905 O OD1 . ASN E 4 122 ? 174.397 186.221 196.441 1.00 51.14  ? 134 ASN A OD1 1 
ATOM 6906 N ND2 . ASN E 4 122 ? 175.397 186.667 194.483 1.00 51.14  ? 134 ASN A ND2 1 
ATOM 6907 N N   . GLY E 4 123 ? 177.001 188.089 199.230 1.00 59.65  ? 135 GLY A N   1 
ATOM 6908 C CA  . GLY E 4 123 ? 178.318 187.733 199.710 1.00 59.65  ? 135 GLY A CA  1 
ATOM 6909 C C   . GLY E 4 123 ? 178.733 188.595 200.882 1.00 59.65  ? 135 GLY A C   1 
ATOM 6910 O O   . GLY E 4 123 ? 179.823 188.424 201.434 1.00 59.65  ? 135 GLY A O   1 
ATOM 6911 N N   . ILE E 4 124 ? 177.870 189.534 201.263 1.00 60.05  ? 136 ILE A N   1 
ATOM 6912 C CA  . ILE E 4 124 ? 177.893 190.074 202.617 1.00 60.05  ? 136 ILE A CA  1 
ATOM 6913 C C   . ILE E 4 124 ? 176.958 189.201 203.436 1.00 60.05  ? 136 ILE A C   1 
ATOM 6914 O O   . ILE E 4 124 ? 177.301 188.760 204.539 1.00 60.05  ? 136 ILE A O   1 
ATOM 6915 C CB  . ILE E 4 124 ? 177.474 191.553 202.676 1.00 60.05  ? 136 ILE A CB  1 
ATOM 6916 C CG1 . ILE E 4 124 ? 178.656 192.459 202.344 1.00 60.05  ? 136 ILE A CG1 1 
ATOM 6917 C CG2 . ILE E 4 124 ? 176.923 191.898 204.047 1.00 60.05  ? 136 ILE A CG2 1 
ATOM 6918 C CD1 . ILE E 4 124 ? 178.288 193.919 202.273 1.00 60.05  ? 136 ILE A CD1 1 
ATOM 6919 N N   . CYS E 4 125 ? 175.770 188.939 202.895 1.00 59.07  ? 137 CYS A N   1 
ATOM 6920 C CA  . CYS E 4 125 ? 174.854 187.984 203.499 1.00 59.07  ? 137 CYS A CA  1 
ATOM 6921 C C   . CYS E 4 125 ? 175.044 186.608 202.878 1.00 59.07  ? 137 CYS A C   1 
ATOM 6922 O O   . CYS E 4 125 ? 174.076 185.982 202.434 1.00 59.07  ? 137 CYS A O   1 
ATOM 6923 C CB  . CYS E 4 125 ? 173.409 188.448 203.334 1.00 59.07  ? 137 CYS A CB  1 
ATOM 6924 S SG  . CYS E 4 125 ? 173.195 190.238 203.341 1.00 59.07  ? 137 CYS A SG  1 
ATOM 6925 N N   . ALA E 4 126 ? 176.286 186.127 202.844 1.00 60.44  ? 138 ALA A N   1 
ATOM 6926 C CA  . ALA E 4 126 ? 176.568 184.835 202.229 1.00 60.44  ? 138 ALA A CA  1 
ATOM 6927 C C   . ALA E 4 126 ? 176.004 183.691 203.061 1.00 60.44  ? 138 ALA A C   1 
ATOM 6928 O O   . ALA E 4 126 ? 175.431 182.740 202.520 1.00 60.44  ? 138 ALA A O   1 
ATOM 6929 C CB  . ALA E 4 126 ? 178.076 184.665 202.030 1.00 60.44  ? 138 ALA A CB  1 
ATOM 6930 N N   . TYR E 4 127 ? 176.152 183.769 204.383 1.00 63.10  ? 139 TYR A N   1 
ATOM 6931 C CA  . TYR E 4 127 ? 175.703 182.692 205.255 1.00 63.10  ? 139 TYR A CA  1 
ATOM 6932 C C   . TYR E 4 127 ? 174.184 182.591 205.265 1.00 63.10  ? 139 TYR A C   1 
ATOM 6933 O O   . TYR E 4 127 ? 173.629 181.552 205.635 1.00 63.10  ? 139 TYR A O   1 
ATOM 6934 C CB  . TYR E 4 127 ? 176.234 182.891 206.673 1.00 63.10  ? 139 TYR A CB  1 
ATOM 6935 C CG  . TYR E 4 127 ? 176.538 181.596 207.388 1.00 63.10  ? 139 TYR A CG  1 
ATOM 6936 C CD1 . TYR E 4 127 ? 175.563 180.946 208.129 1.00 63.10  ? 139 TYR A CD1 1 
ATOM 6937 C CD2 . TYR E 4 127 ? 177.795 181.019 207.313 1.00 63.10  ? 139 TYR A CD2 1 
ATOM 6938 C CE1 . TYR E 4 127 ? 175.835 179.764 208.783 1.00 63.10  ? 139 TYR A CE1 1 
ATOM 6939 C CE2 . TYR E 4 127 ? 178.075 179.836 207.963 1.00 63.10  ? 139 TYR A CE2 1 
ATOM 6940 C CZ  . TYR E 4 127 ? 177.092 179.214 208.696 1.00 63.10  ? 139 TYR A CZ  1 
ATOM 6941 O OH  . TYR E 4 127 ? 177.367 178.033 209.344 1.00 63.10  ? 139 TYR A OH  1 
ATOM 6942 N N   . LEU E 4 128 ? 173.503 183.664 204.867 1.00 64.70  ? 140 LEU A N   1 
ATOM 6943 C CA  . LEU E 4 128 ? 172.062 183.626 204.653 1.00 64.70  ? 140 LEU A CA  1 
ATOM 6944 C C   . LEU E 4 128 ? 171.714 183.346 203.199 1.00 64.70  ? 140 LEU A C   1 
ATOM 6945 O O   . LEU E 4 128 ? 170.535 183.382 202.833 1.00 64.70  ? 140 LEU A O   1 
ATOM 6946 C CB  . LEU E 4 128 ? 171.409 184.935 205.105 1.00 64.70  ? 140 LEU A CB  1 
ATOM 6947 C CG  . LEU E 4 128 ? 169.970 184.801 205.604 1.00 64.70  ? 140 LEU A CG  1 
ATOM 6948 C CD1 . LEU E 4 128 ? 169.766 183.458 206.276 1.00 64.70  ? 140 LEU A CD1 1 
ATOM 6949 C CD2 . LEU E 4 128 ? 169.619 185.925 206.550 1.00 64.70  ? 140 LEU A CD2 1 
ATOM 6950 N N   . ASN E 4 129 ? 172.712 183.084 202.357 1.00 65.83  ? 141 ASN A N   1 
ATOM 6951 C CA  . ASN E 4 129 ? 172.485 182.717 200.971 1.00 65.83  ? 141 ASN A CA  1 
ATOM 6952 C C   . ASN E 4 129 ? 172.831 181.268 200.673 1.00 65.83  ? 141 ASN A C   1 
ATOM 6953 O O   . ASN E 4 129 ? 172.505 180.784 199.584 1.00 65.83  ? 141 ASN A O   1 
ATOM 6954 C CB  . ASN E 4 129 ? 173.300 183.627 200.040 1.00 65.83  ? 141 ASN A CB  1 
ATOM 6955 C CG  . ASN E 4 129 ? 172.671 183.772 198.676 1.00 65.83  ? 141 ASN A CG  1 
ATOM 6956 O OD1 . ASN E 4 129 ? 171.641 184.426 198.523 1.00 65.83  ? 141 ASN A OD1 1 
ATOM 6957 N ND2 . ASN E 4 129 ? 173.285 183.159 197.672 1.00 65.83  ? 141 ASN A ND2 1 
ATOM 6958 N N   . ARG E 4 130 ? 173.472 180.566 201.603 1.00 70.94  ? 142 ARG A N   1 
ATOM 6959 C CA  . ARG E 4 130 ? 173.905 179.187 201.422 1.00 70.94  ? 142 ARG A CA  1 
ATOM 6960 C C   . ARG E 4 130 ? 173.035 178.185 202.155 1.00 70.94  ? 142 ARG A C   1 
ATOM 6961 O O   . ARG E 4 130 ? 172.585 177.208 201.554 1.00 70.94  ? 142 ARG A O   1 
ATOM 6962 C CB  . ARG E 4 130 ? 175.343 179.020 201.916 1.00 70.94  ? 142 ARG A CB  1 
ATOM 6963 C CG  . ARG E 4 130 ? 176.424 179.459 200.959 1.00 70.94  ? 142 ARG A CG  1 
ATOM 6964 C CD  . ARG E 4 130 ? 177.764 178.975 201.471 1.00 70.94  ? 142 ARG A CD  1 
ATOM 6965 N NE  . ARG E 4 130 ? 178.650 180.086 201.788 1.00 70.94  ? 142 ARG A NE  1 
ATOM 6966 C CZ  . ARG E 4 130 ? 179.614 180.036 202.697 1.00 70.94  ? 142 ARG A CZ  1 
ATOM 6967 N NH1 . ARG E 4 130 ? 179.853 178.935 203.390 1.00 70.94  ? 142 ARG A NH1 1 
ATOM 6968 N NH2 . ARG E 4 130 ? 180.348 181.121 202.923 1.00 70.94  ? 142 ARG A NH2 1 
ATOM 6969 N N   . HIS E 4 131 ? 172.795 178.407 203.445 1.00 75.43  ? 143 HIS A N   1 
ATOM 6970 C CA  . HIS E 4 131 ? 172.161 177.408 204.292 1.00 75.43  ? 143 HIS A CA  1 
ATOM 6971 C C   . HIS E 4 131 ? 170.679 177.702 204.473 1.00 75.43  ? 143 HIS A C   1 
ATOM 6972 O O   . HIS E 4 131 ? 169.835 176.873 204.119 1.00 75.43  ? 143 HIS A O   1 
ATOM 6973 C CB  . HIS E 4 131 ? 172.883 177.349 205.637 1.00 75.43  ? 143 HIS A CB  1 
ATOM 6974 C CG  . HIS E 4 131 ? 174.372 177.249 205.506 1.00 75.43  ? 143 HIS A CG  1 
ATOM 6975 N ND1 . HIS E 4 131 ? 175.239 177.694 206.480 1.00 75.43  ? 143 HIS A ND1 1 
ATOM 6976 C CD2 . HIS E 4 131 ? 175.146 176.758 204.510 1.00 75.43  ? 143 HIS A CD2 1 
ATOM 6977 C CE1 . HIS E 4 131 ? 176.483 177.483 206.089 1.00 75.43  ? 143 HIS A CE1 1 
ATOM 6978 N NE2 . HIS E 4 131 ? 176.454 176.914 204.898 1.00 75.43  ? 143 HIS A NE2 1 
ATOM 6979 N N   . TRP E 4 132 ? 170.343 178.875 205.003 1.00 77.82  ? 144 TRP A N   1 
ATOM 6980 C CA  . TRP E 4 132 ? 168.943 179.282 205.092 1.00 77.82  ? 144 TRP A CA  1 
ATOM 6981 C C   . TRP E 4 132 ? 168.621 180.145 203.881 1.00 77.82  ? 144 TRP A C   1 
ATOM 6982 O O   . TRP E 4 132 ? 168.984 181.319 203.841 1.00 77.82  ? 144 TRP A O   1 
ATOM 6983 C CB  . TRP E 4 132 ? 168.661 180.028 206.388 1.00 77.82  ? 144 TRP A CB  1 
ATOM 6984 C CG  . TRP E 4 132 ? 167.196 180.149 206.643 1.00 77.82  ? 144 TRP A CG  1 
ATOM 6985 C CD1 . TRP E 4 132 ? 166.418 179.290 207.358 1.00 77.82  ? 144 TRP A CD1 1 
ATOM 6986 C CD2 . TRP E 4 132 ? 166.317 181.161 206.138 1.00 77.82  ? 144 TRP A CD2 1 
ATOM 6987 N NE1 . TRP E 4 132 ? 165.113 179.717 207.352 1.00 77.82  ? 144 TRP A NE1 1 
ATOM 6988 C CE2 . TRP E 4 132 ? 165.026 180.863 206.608 1.00 77.82  ? 144 TRP A CE2 1 
ATOM 6989 C CE3 . TRP E 4 132 ? 166.500 182.297 205.345 1.00 77.82  ? 144 TRP A CE3 1 
ATOM 6990 C CZ2 . TRP E 4 132 ? 163.925 181.656 206.309 1.00 77.82  ? 144 TRP A CZ2 1 
ATOM 6991 C CZ3 . TRP E 4 132 ? 165.406 183.083 205.051 1.00 77.82  ? 144 TRP A CZ3 1 
ATOM 6992 C CH2 . TRP E 4 132 ? 164.135 182.761 205.532 1.00 77.82  ? 144 TRP A CH2 1 
ATOM 6993 N N   . VAL E 4 133 ? 167.966 179.518 202.896 1.00 75.22  ? 145 VAL A N   1 
ATOM 6994 C CA  . VAL E 4 133 ? 167.464 179.959 201.586 1.00 75.22  ? 145 VAL A CA  1 
ATOM 6995 C C   . VAL E 4 133 ? 167.553 178.705 200.729 1.00 75.22  ? 145 VAL A C   1 
ATOM 6996 O O   . VAL E 4 133 ? 166.845 178.554 199.727 1.00 75.22  ? 145 VAL A O   1 
ATOM 6997 C CB  . VAL E 4 133 ? 168.199 181.157 200.942 1.00 75.22  ? 145 VAL A CB  1 
ATOM 6998 C CG1 . VAL E 4 133 ? 167.731 181.354 199.524 1.00 75.22  ? 145 VAL A CG1 1 
ATOM 6999 C CG2 . VAL E 4 133 ? 167.781 182.452 201.602 1.00 75.22  ? 145 VAL A CG2 1 
ATOM 7000 N N   . ARG E 4 134 ? 168.384 177.762 201.173 1.00 76.75  ? 146 ARG A N   1 
ATOM 7001 C CA  . ARG E 4 134 ? 168.425 176.434 200.577 1.00 76.75  ? 146 ARG A CA  1 
ATOM 7002 C C   . ARG E 4 134 ? 167.832 175.405 201.532 1.00 76.75  ? 146 ARG A C   1 
ATOM 7003 O O   . ARG E 4 134 ? 167.486 174.297 201.105 1.00 76.75  ? 146 ARG A O   1 
ATOM 7004 C CB  . ARG E 4 134 ? 169.860 176.059 200.197 1.00 76.75  ? 146 ARG A CB  1 
ATOM 7005 C CG  . ARG E 4 134 ? 169.976 174.903 199.222 1.00 76.75  ? 146 ARG A CG  1 
ATOM 7006 C CD  . ARG E 4 134 ? 170.410 173.637 199.934 1.00 76.75  ? 146 ARG A CD  1 
ATOM 7007 N NE  . ARG E 4 134 ? 171.816 173.686 200.317 1.00 76.75  ? 146 ARG A NE  1 
ATOM 7008 C CZ  . ARG E 4 134 ? 172.357 172.935 201.266 1.00 76.75  ? 146 ARG A CZ  1 
ATOM 7009 N NH1 . ARG E 4 134 ? 171.637 172.064 201.954 1.00 76.75  ? 146 ARG A NH1 1 
ATOM 7010 N NH2 . ARG E 4 134 ? 173.654 173.063 201.533 1.00 76.75  ? 146 ARG A NH2 1 
ATOM 7011 N N   . ARG E 4 135 ? 167.693 175.754 202.812 1.00 82.60  ? 147 ARG A N   1 
ATOM 7012 C CA  . ARG E 4 135 ? 166.952 174.932 203.759 1.00 82.60  ? 147 ARG A CA  1 
ATOM 7013 C C   . ARG E 4 135 ? 165.594 175.513 204.116 1.00 82.60  ? 147 ARG A C   1 
ATOM 7014 O O   . ARG E 4 135 ? 164.668 174.737 204.367 1.00 82.60  ? 147 ARG A O   1 
ATOM 7015 C CB  . ARG E 4 135 ? 167.763 174.727 205.045 1.00 82.60  ? 147 ARG A CB  1 
ATOM 7016 C CG  . ARG E 4 135 ? 167.234 173.634 205.949 1.00 82.60  ? 147 ARG A CG  1 
ATOM 7017 C CD  . ARG E 4 135 ? 168.060 173.537 207.217 1.00 82.60  ? 147 ARG A CD  1 
ATOM 7018 N NE  . ARG E 4 135 ? 167.805 174.651 208.122 1.00 82.60  ? 147 ARG A NE  1 
ATOM 7019 C CZ  . ARG E 4 135 ? 168.741 175.471 208.579 1.00 82.60  ? 147 ARG A CZ  1 
ATOM 7020 N NH1 . ARG E 4 135 ? 170.011 175.332 208.235 1.00 82.60  ? 147 ARG A NH1 1 
ATOM 7021 N NH2 . ARG E 4 135 ? 168.395 176.455 209.404 1.00 82.60  ? 147 ARG A NH2 1 
ATOM 7022 N N   . GLU E 4 136 ? 165.433 176.837 204.140 1.00 84.61  ? 148 GLU A N   1 
ATOM 7023 C CA  . GLU E 4 136 ? 164.114 177.427 204.217 1.00 84.61  ? 148 GLU A CA  1 
ATOM 7024 C C   . GLU E 4 136 ? 163.298 177.237 202.967 1.00 84.61  ? 148 GLU A C   1 
ATOM 7025 O O   . GLU E 4 136 ? 162.067 177.303 203.013 1.00 84.61  ? 148 GLU A O   1 
ATOM 7026 N N   . CYS E 4 137 ? 163.971 177.004 201.841 1.00 90.00  ? 149 CYS A N   1 
ATOM 7027 C CA  . CYS E 4 137 ? 163.335 176.482 200.641 1.00 90.00  ? 149 CYS A CA  1 
ATOM 7028 C C   . CYS E 4 137 ? 163.712 175.014 200.517 1.00 90.00  ? 149 CYS A C   1 
ATOM 7029 O O   . CYS E 4 137 ? 164.496 174.510 201.328 1.00 90.00  ? 149 CYS A O   1 
ATOM 7030 C CB  . CYS E 4 137 ? 163.767 177.265 199.401 1.00 90.00  ? 149 CYS A CB  1 
ATOM 7031 S SG  . CYS E 4 137 ? 163.259 176.520 197.835 1.00 90.00  ? 149 CYS A SG  1 
ATOM 7032 N N   . ASP E 4 138 ? 163.181 174.332 199.502 1.00 105.58 ? 150 ASP A N   1 
ATOM 7033 C CA  . ASP E 4 138 ? 163.344 172.891 199.356 1.00 105.58 ? 150 ASP A CA  1 
ATOM 7034 C C   . ASP E 4 138 ? 162.850 172.322 200.687 1.00 105.58 ? 150 ASP A C   1 
ATOM 7035 O O   . ASP E 4 138 ? 163.618 171.765 201.479 1.00 105.58 ? 150 ASP A O   1 
ATOM 7036 C CB  . ASP E 4 138 ? 164.807 172.550 198.993 1.00 105.58 ? 150 ASP A CB  1 
ATOM 7037 C CG  . ASP E 4 138 ? 165.239 171.119 199.353 1.00 105.58 ? 150 ASP A CG  1 
ATOM 7038 O OD1 . ASP E 4 138 ? 164.392 170.241 199.623 1.00 105.58 ? 150 ASP A OD1 1 
ATOM 7039 O OD2 . ASP E 4 138 ? 166.463 170.876 199.368 1.00 105.58 ? 150 ASP A OD2 1 
ATOM 7040 N N   . GLU E 4 139 ? 161.568 172.556 200.975 1.00 116.99 ? 151 GLU A N   1 
ATOM 7041 C CA  . GLU E 4 139 ? 160.936 172.125 202.217 1.00 116.99 ? 151 GLU A CA  1 
ATOM 7042 C C   . GLU E 4 139 ? 159.461 172.508 202.209 1.00 116.99 ? 151 GLU A C   1 
ATOM 7043 O O   . GLU E 4 139 ? 158.656 171.883 201.512 1.00 116.99 ? 151 GLU A O   1 
ATOM 7044 C CB  . GLU E 4 139 ? 161.628 172.731 203.444 1.00 116.99 ? 151 GLU A CB  1 
ATOM 7045 C CG  . GLU E 4 139 ? 161.185 172.116 204.769 1.00 116.99 ? 151 GLU A CG  1 
ATOM 7046 C CD  . GLU E 4 139 ? 161.332 173.068 205.938 1.00 116.99 ? 151 GLU A CD  1 
ATOM 7047 O OE1 . GLU E 4 139 ? 160.312 173.357 206.599 1.00 116.99 ? 151 GLU A OE1 1 
ATOM 7048 O OE2 . GLU E 4 139 ? 162.466 173.519 206.203 1.00 116.99 ? 151 GLU A OE2 1 
ATOM 7049 N N   . GLY E 4 140 ? 159.098 173.541 202.974 1.00 125.95 ? 152 GLY A N   1 
ATOM 7050 C CA  . GLY E 4 140 ? 157.696 173.837 203.245 1.00 125.95 ? 152 GLY A CA  1 
ATOM 7051 C C   . GLY E 4 140 ? 157.208 175.173 202.680 1.00 125.95 ? 152 GLY A C   1 
ATOM 7052 O O   . GLY E 4 140 ? 156.028 175.445 202.937 1.00 125.95 ? 152 GLY A O   1 
ATOM 7053 N N   . ARG E 4 141 ? 157.931 176.032 201.961 1.00 113.44 ? 153 ARG A N   1 
ATOM 7054 C CA  . ARG E 4 141 ? 157.324 177.297 201.562 1.00 113.44 ? 153 ARG A CA  1 
ATOM 7055 C C   . ARG E 4 141 ? 157.926 177.890 200.294 1.00 113.44 ? 153 ARG A C   1 
ATOM 7056 O O   . ARG E 4 141 ? 158.931 177.397 199.772 1.00 113.44 ? 153 ARG A O   1 
ATOM 7057 C CB  . ARG E 4 141 ? 157.433 178.319 202.695 1.00 113.44 ? 153 ARG A CB  1 
ATOM 7058 C CG  . ARG E 4 141 ? 158.830 178.477 203.266 1.00 113.44 ? 153 ARG A CG  1 
ATOM 7059 C CD  . ARG E 4 141 ? 158.793 179.178 204.613 1.00 113.44 ? 153 ARG A CD  1 
ATOM 7060 N NE  . ARG E 4 141 ? 158.293 178.308 205.670 1.00 113.44 ? 153 ARG A NE  1 
ATOM 7061 C CZ  . ARG E 4 141 ? 159.060 177.720 206.578 1.00 113.44 ? 153 ARG A CZ  1 
ATOM 7062 N NH1 . ARG E 4 141 ? 160.370 177.899 206.596 1.00 113.44 ? 153 ARG A NH1 1 
ATOM 7063 N NH2 . ARG E 4 141 ? 158.497 176.934 207.491 1.00 113.44 ? 153 ARG A NH2 1 
ATOM 7064 N N   . LYS E 4 142 ? 157.298 178.958 199.800 1.00 108.08 ? 154 LYS A N   1 
ATOM 7065 C CA  . LYS E 4 142 ? 157.767 179.716 198.646 1.00 108.08 ? 154 LYS A CA  1 
ATOM 7066 C C   . LYS E 4 142 ? 158.129 181.126 199.094 1.00 108.08 ? 154 LYS A C   1 
ATOM 7067 O O   . LYS E 4 142 ? 158.145 181.415 200.294 1.00 108.08 ? 154 LYS A O   1 
ATOM 7068 C CB  . LYS E 4 142 ? 156.715 179.787 197.529 1.00 108.08 ? 154 LYS A CB  1 
ATOM 7069 C CG  . LYS E 4 142 ? 155.802 178.573 197.291 1.00 108.08 ? 154 LYS A CG  1 
ATOM 7070 C CD  . LYS E 4 142 ? 156.494 177.224 197.423 1.00 108.08 ? 154 LYS A CD  1 
ATOM 7071 C CE  . LYS E 4 142 ? 155.798 176.172 196.576 1.00 108.08 ? 154 LYS A CE  1 
ATOM 7072 N NZ  . LYS E 4 142 ? 156.170 176.279 195.138 1.00 108.08 ? 154 LYS A NZ  1 
ATOM 7073 N N   . GLY E 4 143 ? 158.415 182.008 198.143 1.00 82.68  ? 155 GLY A N   1 
ATOM 7074 C CA  . GLY E 4 143 ? 158.821 183.358 198.475 1.00 82.68  ? 155 GLY A CA  1 
ATOM 7075 C C   . GLY E 4 143 ? 160.166 183.389 199.168 1.00 82.68  ? 155 GLY A C   1 
ATOM 7076 O O   . GLY E 4 143 ? 160.416 184.231 200.035 1.00 82.68  ? 155 GLY A O   1 
ATOM 7077 N N   . ILE E 4 144 ? 161.041 182.462 198.786 1.00 74.57  ? 156 ILE A N   1 
ATOM 7078 C CA  . ILE E 4 144 ? 162.405 182.413 199.295 1.00 74.57  ? 156 ILE A CA  1 
ATOM 7079 C C   . ILE E 4 144 ? 163.347 182.431 198.101 1.00 74.57  ? 156 ILE A C   1 
ATOM 7080 O O   . ILE E 4 144 ? 163.248 181.587 197.204 1.00 74.57  ? 156 ILE A O   1 
ATOM 7081 C CB  . ILE E 4 144 ? 162.637 181.169 200.170 1.00 74.57  ? 156 ILE A CB  1 
ATOM 7082 C CG1 . ILE E 4 144 ? 162.113 181.406 201.587 1.00 74.57  ? 156 ILE A CG1 1 
ATOM 7083 C CG2 . ILE E 4 144 ? 164.113 180.811 200.209 1.00 74.57  ? 156 ILE A CG2 1 
ATOM 7084 C CD1 . ILE E 4 144 ? 162.628 182.672 202.222 1.00 74.57  ? 156 ILE A CD1 1 
ATOM 7085 N N   . TYR E 4 145 ? 164.259 183.397 198.073 1.00 69.01  ? 157 TYR A N   1 
ATOM 7086 C CA  . TYR E 4 145 ? 165.153 183.547 196.936 1.00 69.01  ? 157 TYR A CA  1 
ATOM 7087 C C   . TYR E 4 145 ? 166.532 183.934 197.442 1.00 69.01  ? 157 TYR A C   1 
ATOM 7088 O O   . TYR E 4 145 ? 166.664 184.481 198.538 1.00 69.01  ? 157 TYR A O   1 
ATOM 7089 C CB  . TYR E 4 145 ? 164.644 184.610 195.956 1.00 69.01  ? 157 TYR A CB  1 
ATOM 7090 C CG  . TYR E 4 145 ? 163.178 184.503 195.602 1.00 69.01  ? 157 TYR A CG  1 
ATOM 7091 C CD1 . TYR E 4 145 ? 162.210 185.130 196.374 1.00 69.01  ? 157 TYR A CD1 1 
ATOM 7092 C CD2 . TYR E 4 145 ? 162.763 183.787 194.488 1.00 69.01  ? 157 TYR A CD2 1 
ATOM 7093 C CE1 . TYR E 4 145 ? 160.871 185.041 196.051 1.00 69.01  ? 157 TYR A CE1 1 
ATOM 7094 C CE2 . TYR E 4 145 ? 161.426 183.692 194.158 1.00 69.01  ? 157 TYR A CE2 1 
ATOM 7095 C CZ  . TYR E 4 145 ? 160.485 184.321 194.943 1.00 69.01  ? 157 TYR A CZ  1 
ATOM 7096 O OH  . TYR E 4 145 ? 159.152 184.230 194.620 1.00 69.01  ? 157 TYR A OH  1 
ATOM 7097 N N   . GLU E 4 146 ? 167.553 183.639 196.641 1.00 61.82  ? 158 GLU A N   1 
ATOM 7098 C CA  . GLU E 4 146 ? 168.868 184.207 196.889 1.00 61.82  ? 158 GLU A CA  1 
ATOM 7099 C C   . GLU E 4 146 ? 168.765 185.724 196.863 1.00 61.82  ? 158 GLU A C   1 
ATOM 7100 O O   . GLU E 4 146 ? 168.021 186.293 196.061 1.00 61.82  ? 158 GLU A O   1 
ATOM 7101 C CB  . GLU E 4 146 ? 169.876 183.723 195.841 1.00 61.82  ? 158 GLU A CB  1 
ATOM 7102 C CG  . GLU E 4 146 ? 170.273 182.251 195.944 1.00 61.82  ? 158 GLU A CG  1 
ATOM 7103 C CD  . GLU E 4 146 ? 169.132 181.289 195.659 1.00 61.82  ? 158 GLU A CD  1 
ATOM 7104 O OE1 . GLU E 4 146 ? 169.266 180.093 195.995 1.00 61.82  ? 158 GLU A OE1 1 
ATOM 7105 O OE2 . GLU E 4 146 ? 168.106 181.722 195.094 1.00 61.82  ? 158 GLU A OE2 1 
ATOM 7106 N N   . ILE E 4 147 ? 169.505 186.378 197.755 1.00 50.31  ? 159 ILE A N   1 
ATOM 7107 C CA  . ILE E 4 147 ? 169.323 187.805 197.997 1.00 50.31  ? 159 ILE A CA  1 
ATOM 7108 C C   . ILE E 4 147 ? 169.590 188.602 196.726 1.00 50.31  ? 159 ILE A C   1 
ATOM 7109 O O   . ILE E 4 147 ? 168.925 189.613 196.467 1.00 50.31  ? 159 ILE A O   1 
ATOM 7110 C CB  . ILE E 4 147 ? 170.204 188.277 199.167 1.00 50.31  ? 159 ILE A CB  1 
ATOM 7111 C CG1 . ILE E 4 147 ? 169.496 187.968 200.484 1.00 50.31  ? 159 ILE A CG1 1 
ATOM 7112 C CG2 . ILE E 4 147 ? 170.487 189.762 199.077 1.00 50.31  ? 159 ILE A CG2 1 
ATOM 7113 C CD1 . ILE E 4 147 ? 170.310 188.275 201.703 1.00 50.31  ? 159 ILE A CD1 1 
ATOM 7114 N N   . TYR E 4 148 ? 170.531 188.143 195.902 1.00 46.35  ? 160 TYR A N   1 
ATOM 7115 C CA  . TYR E 4 148 ? 170.739 188.758 194.585 1.00 46.35  ? 160 TYR A CA  1 
ATOM 7116 C C   . TYR E 4 148 ? 169.492 188.586 193.722 1.00 46.35  ? 160 TYR A C   1 
ATOM 7117 O O   . TYR E 4 148 ? 169.004 189.548 193.123 1.00 46.35  ? 160 TYR A O   1 
ATOM 7118 C CB  . TYR E 4 148 ? 171.962 188.165 193.887 1.00 46.35  ? 160 TYR A CB  1 
ATOM 7119 C CG  . TYR E 4 148 ? 172.181 188.746 192.509 1.00 46.35  ? 160 TYR A CG  1 
ATOM 7120 C CD1 . TYR E 4 148 ? 172.012 190.103 192.275 1.00 46.35  ? 160 TYR A CD1 1 
ATOM 7121 C CD2 . TYR E 4 148 ? 172.532 187.939 191.439 1.00 46.35  ? 160 TYR A CD2 1 
ATOM 7122 C CE1 . TYR E 4 148 ? 172.202 190.642 191.022 1.00 46.35  ? 160 TYR A CE1 1 
ATOM 7123 C CE2 . TYR E 4 148 ? 172.724 188.471 190.179 1.00 46.35  ? 160 TYR A CE2 1 
ATOM 7124 C CZ  . TYR E 4 148 ? 172.556 189.824 189.978 1.00 46.35  ? 160 TYR A CZ  1 
ATOM 7125 O OH  . TYR E 4 148 ? 172.745 190.362 188.728 1.00 46.35  ? 160 TYR A OH  1 
ATOM 7126 N N   . SER E 4 149 ? 168.968 187.364 193.655 1.00 47.86  ? 161 SER A N   1 
ATOM 7127 C CA  . SER E 4 149 ? 167.784 187.109 192.845 1.00 47.86  ? 161 SER A CA  1 
ATOM 7128 C C   . SER E 4 149 ? 166.557 187.718 193.506 1.00 47.86  ? 161 SER A C   1 
ATOM 7129 O O   . SER E 4 149 ? 165.506 187.852 192.874 1.00 47.86  ? 161 SER A O   1 
ATOM 7130 C CB  . SER E 4 149 ? 167.587 185.610 192.625 1.00 47.86  ? 161 SER A CB  1 
ATOM 7131 O OG  . SER E 4 149 ? 166.844 185.037 193.684 1.00 47.86  ? 161 SER A OG  1 
ATOM 7132 N N   . LEU E 4 150 ? 166.679 188.085 194.781 1.00 46.43  ? 162 LEU A N   1 
ATOM 7133 C CA  . LEU E 4 150 ? 165.636 188.831 195.475 1.00 46.43  ? 162 LEU A CA  1 
ATOM 7134 C C   . LEU E 4 150 ? 165.666 190.299 195.069 1.00 46.43  ? 162 LEU A C   1 
ATOM 7135 O O   . LEU E 4 150 ? 164.621 190.954 195.014 1.00 46.43  ? 162 LEU A O   1 
ATOM 7136 C CB  . LEU E 4 150 ? 165.796 188.668 196.995 1.00 46.43  ? 162 LEU A CB  1 
ATOM 7137 C CG  . LEU E 4 150 ? 164.848 189.355 197.986 1.00 46.43  ? 162 LEU A CG  1 
ATOM 7138 C CD1 . LEU E 4 150 ? 165.233 190.802 198.264 1.00 46.43  ? 162 LEU A CD1 1 
ATOM 7139 C CD2 . LEU E 4 150 ? 163.411 189.263 197.505 1.00 46.43  ? 162 LEU A CD2 1 
ATOM 7140 N N   . ALA E 4 151 ? 166.855 190.830 194.787 1.00 45.10  ? 163 ALA A N   1 
ATOM 7141 C CA  . ALA E 4 151 ? 166.986 192.203 194.321 1.00 45.10  ? 163 ALA A CA  1 
ATOM 7142 C C   . ALA E 4 151 ? 166.320 192.384 192.965 1.00 45.10  ? 163 ALA A C   1 
ATOM 7143 O O   . ALA E 4 151 ? 165.592 193.358 192.753 1.00 45.10  ? 163 ALA A O   1 
ATOM 7144 C CB  . ALA E 4 151 ? 168.456 192.609 194.243 1.00 45.10  ? 163 ALA A CB  1 
ATOM 7145 N N   . LEU E 4 152 ? 166.565 191.462 192.034 1.00 42.97  ? 164 LEU A N   1 
ATOM 7146 C CA  . LEU E 4 152 ? 165.878 191.533 190.752 1.00 42.97  ? 164 LEU A CA  1 
ATOM 7147 C C   . LEU E 4 152 ? 164.608 190.695 190.778 1.00 42.97  ? 164 LEU A C   1 
ATOM 7148 O O   . LEU E 4 152 ? 164.336 189.932 189.846 1.00 42.97  ? 164 LEU A O   1 
ATOM 7149 C CB  . LEU E 4 152 ? 166.798 191.066 189.626 1.00 42.97  ? 164 LEU A CB  1 
ATOM 7150 C CG  . LEU E 4 152 ? 168.266 191.446 189.799 1.00 42.97  ? 164 LEU A CG  1 
ATOM 7151 C CD1 . LEU E 4 152 ? 169.109 190.811 188.716 1.00 42.97  ? 164 LEU A CD1 1 
ATOM 7152 C CD2 . LEU E 4 152 ? 168.424 192.954 189.782 1.00 42.97  ? 164 LEU A CD2 1 
ATOM 7153 N N   . VAL E 4 153 ? 163.830 190.830 191.848 1.00 48.86  ? 165 VAL A N   1 
ATOM 7154 C CA  . VAL E 4 153 ? 162.437 190.409 191.878 1.00 48.86  ? 165 VAL A CA  1 
ATOM 7155 C C   . VAL E 4 153 ? 161.675 191.564 192.508 1.00 48.86  ? 165 VAL A C   1 
ATOM 7156 O O   . VAL E 4 153 ? 160.480 191.759 192.257 1.00 48.86  ? 165 VAL A O   1 
ATOM 7157 C CB  . VAL E 4 153 ? 162.262 189.087 192.648 1.00 48.86  ? 165 VAL A CB  1 
ATOM 7158 C CG1 . VAL E 4 153 ? 160.883 188.983 193.277 1.00 48.86  ? 165 VAL A CG1 1 
ATOM 7159 C CG2 . VAL E 4 153 ? 162.506 187.910 191.724 1.00 48.86  ? 165 VAL A CG2 1 
ATOM 7160 N N   . THR E 4 154 ? 162.395 192.381 193.280 1.00 49.65  ? 166 THR A N   1 
ATOM 7161 C CA  . THR E 4 154 ? 161.846 193.616 193.820 1.00 49.65  ? 166 THR A CA  1 
ATOM 7162 C C   . THR E 4 154 ? 162.253 194.799 192.956 1.00 49.65  ? 166 THR A C   1 
ATOM 7163 O O   . THR E 4 154 ? 161.796 195.924 193.181 1.00 49.65  ? 166 THR A O   1 
ATOM 7164 C CB  . THR E 4 154 ? 162.290 193.848 195.262 1.00 49.65  ? 166 THR A CB  1 
ATOM 7165 O OG1 . THR E 4 154 ? 161.643 195.017 195.776 1.00 49.65  ? 166 THR A OG1 1 
ATOM 7166 C CG2 . THR E 4 154 ? 163.786 194.058 195.322 1.00 49.65  ? 166 THR A CG2 1 
ATOM 7167 N N   . TRP E 4 155 ? 163.116 194.563 191.966 1.00 50.23  ? 167 TRP A N   1 
ATOM 7168 C CA  . TRP E 4 155 ? 163.353 195.532 190.910 1.00 50.23  ? 167 TRP A CA  1 
ATOM 7169 C C   . TRP E 4 155 ? 162.154 195.668 189.989 1.00 50.23  ? 167 TRP A C   1 
ATOM 7170 O O   . TRP E 4 155 ? 162.071 196.650 189.244 1.00 50.23  ? 167 TRP A O   1 
ATOM 7171 C CB  . TRP E 4 155 ? 164.588 195.146 190.085 1.00 50.23  ? 167 TRP A CB  1 
ATOM 7172 C CG  . TRP E 4 155 ? 164.971 196.151 189.037 1.00 50.23  ? 167 TRP A CG  1 
ATOM 7173 C CD1 . TRP E 4 155 ? 164.897 195.993 187.689 1.00 50.23  ? 167 TRP A CD1 1 
ATOM 7174 C CD2 . TRP E 4 155 ? 165.530 197.452 189.257 1.00 50.23  ? 167 TRP A CD2 1 
ATOM 7175 N NE1 . TRP E 4 155 ? 165.353 197.120 187.053 1.00 50.23  ? 167 TRP A NE1 1 
ATOM 7176 C CE2 . TRP E 4 155 ? 165.750 198.030 187.995 1.00 50.23  ? 167 TRP A CE2 1 
ATOM 7177 C CE3 . TRP E 4 155 ? 165.858 198.185 190.397 1.00 50.23  ? 167 TRP A CE3 1 
ATOM 7178 C CZ2 . TRP E 4 155 ? 166.281 199.306 187.842 1.00 50.23  ? 167 TRP A CZ2 1 
ATOM 7179 C CZ3 . TRP E 4 155 ? 166.385 199.454 190.241 1.00 50.23  ? 167 TRP A CZ3 1 
ATOM 7180 C CH2 . TRP E 4 155 ? 166.590 200.001 188.974 1.00 50.23  ? 167 TRP A CH2 1 
ATOM 7181 N N   . ARG E 4 156 ? 161.223 194.714 190.025 1.00 57.36  ? 168 ARG A N   1 
ATOM 7182 C CA  . ARG E 4 156 ? 159.936 194.897 189.372 1.00 57.36  ? 168 ARG A CA  1 
ATOM 7183 C C   . ARG E 4 156 ? 159.013 195.656 190.316 1.00 57.36  ? 168 ARG A C   1 
ATOM 7184 O O   . ARG E 4 156 ? 157.858 195.273 190.531 1.00 57.36  ? 168 ARG A O   1 
ATOM 7185 C CB  . ARG E 4 156 ? 159.336 193.551 188.967 1.00 57.36  ? 168 ARG A CB  1 
ATOM 7186 C CG  . ARG E 4 156 ? 159.813 193.065 187.611 1.00 57.36  ? 168 ARG A CG  1 
ATOM 7187 C CD  . ARG E 4 156 ? 159.002 191.874 187.124 1.00 57.36  ? 168 ARG A CD  1 
ATOM 7188 N NE  . ARG E 4 156 ? 159.245 190.661 187.896 1.00 57.36  ? 168 ARG A NE  1 
ATOM 7189 C CZ  . ARG E 4 156 ? 160.423 190.066 188.027 1.00 57.36  ? 168 ARG A CZ  1 
ATOM 7190 N NH1 . ARG E 4 156 ? 161.498 190.504 187.391 1.00 57.36  ? 168 ARG A NH1 1 
ATOM 7191 N NH2 . ARG E 4 156 ? 160.524 188.993 188.804 1.00 57.36  ? 168 ARG A NH2 1 
ATOM 7192 N N   . ASP E 4 157 ? 159.548 196.737 190.890 1.00 60.90  ? 169 ASP A N   1 
ATOM 7193 C CA  . ASP E 4 157 ? 158.747 197.777 191.523 1.00 60.90  ? 169 ASP A CA  1 
ATOM 7194 C C   . ASP E 4 157 ? 159.134 199.131 190.946 1.00 60.90  ? 169 ASP A C   1 
ATOM 7195 O O   . ASP E 4 157 ? 158.572 200.155 191.352 1.00 60.90  ? 169 ASP A O   1 
ATOM 7196 C CB  . ASP E 4 157 ? 158.933 197.783 193.040 1.00 60.90  ? 169 ASP A CB  1 
ATOM 7197 C CG  . ASP E 4 157 ? 157.915 196.925 193.754 1.00 60.90  ? 169 ASP A CG  1 
ATOM 7198 O OD1 . ASP E 4 157 ? 157.535 195.868 193.209 1.00 60.90  ? 169 ASP A OD1 1 
ATOM 7199 O OD2 . ASP E 4 157 ? 157.494 197.310 194.864 1.00 60.90  ? 169 ASP A OD2 1 
ATOM 7200 N N   . CYS E 4 158 ? 160.094 199.153 190.024 1.00 69.35  ? 170 CYS A N   1 
ATOM 7201 C CA  . CYS E 4 158 ? 160.480 200.345 189.288 1.00 69.35  ? 170 CYS A CA  1 
ATOM 7202 C C   . CYS E 4 158 ? 160.329 200.050 187.800 1.00 69.35  ? 170 CYS A C   1 
ATOM 7203 O O   . CYS E 4 158 ? 160.431 200.956 186.969 1.00 69.35  ? 170 CYS A O   1 
ATOM 7204 C CB  . CYS E 4 158 ? 161.911 200.755 189.655 1.00 69.35  ? 170 CYS A CB  1 
ATOM 7205 S SG  . CYS E 4 158 ? 162.702 201.998 188.606 1.00 69.35  ? 170 CYS A SG  1 
ATOM 7206 N N   . LEU E 4 159 ? 160.055 198.788 187.458 1.00 61.39  ? 171 LEU A N   1 
ATOM 7207 C CA  . LEU E 4 159 ? 159.804 198.376 186.079 1.00 61.39  ? 171 LEU A CA  1 
ATOM 7208 C C   . LEU E 4 159 ? 158.316 198.252 185.765 1.00 61.39  ? 171 LEU A C   1 
ATOM 7209 O O   . LEU E 4 159 ? 157.859 198.788 184.752 1.00 61.39  ? 171 LEU A O   1 
ATOM 7210 C CB  . LEU E 4 159 ? 160.506 197.049 185.770 1.00 61.39  ? 171 LEU A CB  1 
ATOM 7211 C CG  . LEU E 4 159 ? 160.001 196.343 184.508 1.00 61.39  ? 171 LEU A CG  1 
ATOM 7212 C CD1 . LEU E 4 159 ? 160.426 197.097 183.264 1.00 61.39  ? 171 LEU A CD1 1 
ATOM 7213 C CD2 . LEU E 4 159 ? 160.488 194.911 184.446 1.00 61.39  ? 171 LEU A CD2 1 
ATOM 7214 N N   . PHE E 4 160 ? 157.539 197.565 186.609 1.00 61.35  ? 172 PHE A N   1 
ATOM 7215 C CA  . PHE E 4 160 ? 156.091 197.582 186.421 1.00 61.35  ? 172 PHE A CA  1 
ATOM 7216 C C   . PHE E 4 160 ? 155.524 198.851 187.039 1.00 61.35  ? 172 PHE A C   1 
ATOM 7217 O O   . PHE E 4 160 ? 154.454 198.835 187.651 1.00 61.35  ? 172 PHE A O   1 
ATOM 7218 C CB  . PHE E 4 160 ? 155.429 196.354 187.054 1.00 61.35  ? 172 PHE A CB  1 
ATOM 7219 C CG  . PHE E 4 160 ? 155.433 195.133 186.180 1.00 61.35  ? 172 PHE A CG  1 
ATOM 7220 C CD1 . PHE E 4 160 ? 155.408 195.247 184.801 1.00 61.35  ? 172 PHE A CD1 1 
ATOM 7221 C CD2 . PHE E 4 160 ? 155.437 193.866 186.741 1.00 61.35  ? 172 PHE A CD2 1 
ATOM 7222 C CE1 . PHE E 4 160 ? 155.403 194.120 183.999 1.00 61.35  ? 172 PHE A CE1 1 
ATOM 7223 C CE2 . PHE E 4 160 ? 155.432 192.737 185.945 1.00 61.35  ? 172 PHE A CE2 1 
ATOM 7224 C CZ  . PHE E 4 160 ? 155.416 192.864 184.572 1.00 61.35  ? 172 PHE A CZ  1 
ATOM 7225 N N   . ARG E 4 161 ? 156.203 199.955 186.765 1.00 68.52  ? 173 ARG A N   1 
ATOM 7226 C CA  . ARG E 4 161 ? 156.084 201.360 187.125 1.00 68.52  ? 173 ARG A CA  1 
ATOM 7227 C C   . ARG E 4 161 ? 157.024 202.023 186.130 1.00 68.52  ? 173 ARG A C   1 
ATOM 7228 O O   . ARG E 4 161 ? 158.058 201.424 185.810 1.00 68.52  ? 173 ARG A O   1 
ATOM 7229 C CB  . ARG E 4 161 ? 156.499 201.665 188.572 1.00 68.52  ? 173 ARG A CB  1 
ATOM 7230 C CG  . ARG E 4 161 ? 155.393 201.751 189.635 1.00 68.52  ? 173 ARG A CG  1 
ATOM 7231 C CD  . ARG E 4 161 ? 154.757 200.433 190.002 1.00 68.52  ? 173 ARG A CD  1 
ATOM 7232 N NE  . ARG E 4 161 ? 154.481 200.320 191.429 1.00 68.52  ? 173 ARG A NE  1 
ATOM 7233 C CZ  . ARG E 4 161 ? 153.936 199.255 192.001 1.00 68.52  ? 173 ARG A CZ  1 
ATOM 7234 N NH1 . ARG E 4 161 ? 153.595 198.190 191.294 1.00 68.52  ? 173 ARG A NH1 1 
ATOM 7235 N NH2 . ARG E 4 161 ? 153.726 199.260 193.314 1.00 68.52  ? 173 ARG A NH2 1 
ATOM 7236 N N   . PRO E 4 162 ? 156.773 203.271 185.702 1.00 74.64  ? 174 PRO A N   1 
ATOM 7237 C CA  . PRO E 4 162 ? 157.200 203.720 184.363 1.00 74.64  ? 174 PRO A CA  1 
ATOM 7238 C C   . PRO E 4 162 ? 157.880 202.696 183.463 1.00 74.64  ? 174 PRO A C   1 
ATOM 7239 O O   . PRO E 4 162 ? 157.414 201.559 183.331 1.00 74.64  ? 174 PRO A O   1 
ATOM 7240 C CB  . PRO E 4 162 ? 158.117 204.903 184.736 1.00 74.64  ? 174 PRO A CB  1 
ATOM 7241 C CG  . PRO E 4 162 ? 158.663 204.390 186.012 1.00 74.64  ? 174 PRO A CG  1 
ATOM 7242 C CD  . PRO E 4 162 ? 157.275 204.311 186.602 1.00 74.64  ? 174 PRO A CD  1 
ATOM 7243 N N   . LEU E 4 163 ? 158.931 203.126 182.770 1.00 77.47  ? 175 LEU A N   1 
ATOM 7244 C CA  . LEU E 4 163 ? 159.760 202.240 181.959 1.00 77.47  ? 175 LEU A CA  1 
ATOM 7245 C C   . LEU E 4 163 ? 158.951 201.425 180.959 1.00 77.47  ? 175 LEU A C   1 
ATOM 7246 O O   . LEU E 4 163 ? 158.954 201.724 179.761 1.00 77.47  ? 175 LEU A O   1 
ATOM 7247 C CB  . LEU E 4 163 ? 160.569 201.288 182.842 1.00 77.47  ? 175 LEU A CB  1 
ATOM 7248 C CG  . LEU E 4 163 ? 161.883 201.750 183.475 1.00 77.47  ? 175 LEU A CG  1 
ATOM 7249 C CD1 . LEU E 4 163 ? 161.822 203.174 184.020 1.00 77.47  ? 175 LEU A CD1 1 
ATOM 7250 C CD2 . LEU E 4 163 ? 162.273 200.769 184.555 1.00 77.47  ? 175 LEU A CD2 1 
ATOM 7251 N N   . ASN E 4 164 ? 158.230 200.414 181.451 1.00 70.42  ? 176 ASN A N   1 
ATOM 7252 C CA  . ASN E 4 164 ? 157.509 199.475 180.599 1.00 70.42  ? 176 ASN A CA  1 
ATOM 7253 C C   . ASN E 4 164 ? 156.575 200.198 179.638 1.00 70.42  ? 176 ASN A C   1 
ATOM 7254 O O   . ASN E 4 164 ? 156.135 199.624 178.637 1.00 70.42  ? 176 ASN A O   1 
ATOM 7255 C CB  . ASN E 4 164 ? 156.722 198.481 181.450 1.00 70.42  ? 176 ASN A CB  1 
ATOM 7256 C CG  . ASN E 4 164 ? 156.600 197.124 180.793 1.00 70.42  ? 176 ASN A CG  1 
ATOM 7257 O OD1 . ASN E 4 164 ? 157.043 196.929 179.662 1.00 70.42  ? 176 ASN A OD1 1 
ATOM 7258 N ND2 . ASN E 4 164 ? 155.993 196.176 181.498 1.00 70.42  ? 176 ASN A ND2 1 
ATOM 7259 N N   . LYS E 4 165 ? 156.268 201.457 179.939 1.00 75.91  ? 177 LYS A N   1 
ATOM 7260 C CA  . LYS E 4 165 ? 155.524 202.305 179.022 1.00 75.91  ? 177 LYS A CA  1 
ATOM 7261 C C   . LYS E 4 165 ? 156.336 203.544 178.668 1.00 75.91  ? 177 LYS A C   1 
ATOM 7262 O O   . LYS E 4 165 ? 156.044 204.218 177.675 1.00 75.91  ? 177 LYS A O   1 
ATOM 7263 C CB  . LYS E 4 165 ? 154.176 202.698 179.633 1.00 75.91  ? 177 LYS A CB  1 
ATOM 7264 C CG  . LYS E 4 165 ? 153.051 202.845 178.621 1.00 75.91  ? 177 LYS A CG  1 
ATOM 7265 C CD  . LYS E 4 165 ? 152.774 201.537 177.887 1.00 75.91  ? 177 LYS A CD  1 
ATOM 7266 C CE  . LYS E 4 165 ? 152.584 200.374 178.853 1.00 75.91  ? 177 LYS A CE  1 
ATOM 7267 N NZ  . LYS E 4 165 ? 151.959 199.195 178.192 1.00 75.91  ? 177 LYS A NZ  1 
ATOM 7268 N N   . GLN E 4 166 ? 157.357 203.859 179.470 1.00 72.82  ? 178 GLN A N   1 
ATOM 7269 C CA  . GLN E 4 166 ? 158.021 205.149 179.325 1.00 72.82  ? 178 GLN A CA  1 
ATOM 7270 C C   . GLN E 4 166 ? 159.411 205.075 178.700 1.00 72.82  ? 178 GLN A C   1 
ATOM 7271 O O   . GLN E 4 166 ? 159.907 206.113 178.252 1.00 72.82  ? 178 GLN A O   1 
ATOM 7272 C CB  . GLN E 4 166 ? 158.095 205.853 180.679 1.00 72.82  ? 178 GLN A CB  1 
ATOM 7273 C CG  . GLN E 4 166 ? 156.758 205.913 181.394 1.00 72.82  ? 178 GLN A CG  1 
ATOM 7274 C CD  . GLN E 4 166 ? 156.703 207.008 182.435 1.00 72.82  ? 178 GLN A CD  1 
ATOM 7275 O OE1 . GLN E 4 166 ? 157.565 207.885 182.476 1.00 72.82  ? 178 GLN A OE1 1 
ATOM 7276 N NE2 . GLN E 4 166 ? 155.685 206.963 183.287 1.00 72.82  ? 178 GLN A NE2 1 
ATOM 7277 N N   . VAL E 4 167 ? 160.063 203.913 178.655 1.00 67.98  ? 179 VAL A N   1 
ATOM 7278 C CA  . VAL E 4 167 ? 161.276 203.742 177.860 1.00 67.98  ? 179 VAL A CA  1 
ATOM 7279 C C   . VAL E 4 167 ? 160.985 202.973 176.578 1.00 67.98  ? 179 VAL A C   1 
ATOM 7280 O O   . VAL E 4 167 ? 161.511 203.304 175.516 1.00 67.98  ? 179 VAL A O   1 
ATOM 7281 C CB  . VAL E 4 167 ? 162.414 203.064 178.663 1.00 67.98  ? 179 VAL A CB  1 
ATOM 7282 C CG1 . VAL E 4 167 ? 163.102 204.056 179.595 1.00 67.98  ? 179 VAL A CG1 1 
ATOM 7283 C CG2 . VAL E 4 167 ? 161.962 201.813 179.371 1.00 67.98  ? 179 VAL A CG2 1 
ATOM 7284 N N   . THR E 4 168 ? 160.130 201.949 176.656 1.00 67.78  ? 180 THR A N   1 
ATOM 7285 C CA  . THR E 4 168 ? 159.745 201.225 175.449 1.00 67.78  ? 180 THR A CA  1 
ATOM 7286 C C   . THR E 4 168 ? 159.161 202.175 174.413 1.00 67.78  ? 180 THR A C   1 
ATOM 7287 O O   . THR E 4 168 ? 159.438 202.047 173.216 1.00 67.78  ? 180 THR A O   1 
ATOM 7288 C CB  . THR E 4 168 ? 158.753 200.114 175.794 1.00 67.78  ? 180 THR A CB  1 
ATOM 7289 O OG1 . THR E 4 168 ? 159.443 199.047 176.455 1.00 67.78  ? 180 THR A OG1 1 
ATOM 7290 C CG2 . THR E 4 168 ? 158.086 199.573 174.537 1.00 67.78  ? 180 THR A CG2 1 
ATOM 7291 N N   . ASN E 4 169 ? 158.383 203.156 174.855 1.00 70.61  ? 181 ASN A N   1 
ATOM 7292 C CA  . ASN E 4 169 ? 157.939 204.217 173.957 1.00 70.61  ? 181 ASN A CA  1 
ATOM 7293 C C   . ASN E 4 169 ? 158.993 205.296 173.756 1.00 70.61  ? 181 ASN A C   1 
ATOM 7294 O O   . ASN E 4 169 ? 158.764 206.214 172.959 1.00 70.61  ? 181 ASN A O   1 
ATOM 7295 C CB  . ASN E 4 169 ? 156.646 204.843 174.480 1.00 70.61  ? 181 ASN A CB  1 
ATOM 7296 C CG  . ASN E 4 169 ? 155.412 204.100 174.015 1.00 70.61  ? 181 ASN A CG  1 
ATOM 7297 O OD1 . ASN E 4 169 ? 155.475 202.917 173.683 1.00 70.61  ? 181 ASN A OD1 1 
ATOM 7298 N ND2 . ASN E 4 169 ? 154.279 204.791 173.990 1.00 70.61  ? 181 ASN A ND2 1 
ATOM 7299 N N   . ALA E 4 170 ? 160.130 205.220 174.448 1.00 63.25  ? 182 ALA A N   1 
ATOM 7300 C CA  . ALA E 4 170 ? 161.212 206.184 174.291 1.00 63.25  ? 182 ALA A CA  1 
ATOM 7301 C C   . ALA E 4 170 ? 162.393 205.595 173.531 1.00 63.25  ? 182 ALA A C   1 
ATOM 7302 O O   . ALA E 4 170 ? 163.018 206.295 172.730 1.00 63.25  ? 182 ALA A O   1 
ATOM 7303 C CB  . ALA E 4 170 ? 161.666 206.703 175.661 1.00 63.25  ? 182 ALA A CB  1 
ATOM 7304 N N   . VAL E 4 171 ? 162.729 204.326 173.769 1.00 58.10  ? 183 VAL A N   1 
ATOM 7305 C CA  . VAL E 4 171 ? 163.786 203.666 173.009 1.00 58.10  ? 183 VAL A CA  1 
ATOM 7306 C C   . VAL E 4 171 ? 163.393 203.642 171.540 1.00 58.10  ? 183 VAL A C   1 
ATOM 7307 O O   . VAL E 4 171 ? 164.229 203.873 170.660 1.00 58.10  ? 183 VAL A O   1 
ATOM 7308 C CB  . VAL E 4 171 ? 164.073 202.241 173.515 1.00 58.10  ? 183 VAL A CB  1 
ATOM 7309 C CG1 . VAL E 4 171 ? 165.311 201.701 172.839 1.00 58.10  ? 183 VAL A CG1 1 
ATOM 7310 C CG2 . VAL E 4 171 ? 164.276 202.229 175.009 1.00 58.10  ? 183 VAL A CG2 1 
ATOM 7311 N N   . LEU E 4 172 ? 162.117 203.360 171.264 1.00 56.58  ? 184 LEU A N   1 
ATOM 7312 C CA  . LEU E 4 172 ? 161.649 203.355 169.882 1.00 56.58  ? 184 LEU A CA  1 
ATOM 7313 C C   . LEU E 4 172 ? 161.858 204.715 169.236 1.00 56.58  ? 184 LEU A C   1 
ATOM 7314 O O   . LEU E 4 172 ? 162.263 204.806 168.073 1.00 56.58  ? 184 LEU A O   1 
ATOM 7315 C CB  . LEU E 4 172 ? 160.178 202.949 169.810 1.00 56.58  ? 184 LEU A CB  1 
ATOM 7316 C CG  . LEU E 4 172 ? 159.854 201.493 170.132 1.00 56.58  ? 184 LEU A CG  1 
ATOM 7317 C CD1 . LEU E 4 172 ? 158.359 201.330 170.332 1.00 56.58  ? 184 LEU A CD1 1 
ATOM 7318 C CD2 . LEU E 4 172 ? 160.360 200.577 169.038 1.00 56.58  ? 184 LEU A CD2 1 
ATOM 7319 N N   . LYS E 4 173 ? 161.594 205.788 169.983 1.00 59.01  ? 185 LYS A N   1 
ATOM 7320 C CA  . LYS E 4 173 ? 161.840 207.126 169.458 1.00 59.01  ? 185 LYS A CA  1 
ATOM 7321 C C   . LYS E 4 173 ? 163.309 207.314 169.109 1.00 59.01  ? 185 LYS A C   1 
ATOM 7322 O O   . LYS E 4 173 ? 163.642 207.972 168.117 1.00 59.01  ? 185 LYS A O   1 
ATOM 7323 C CB  . LYS E 4 173 ? 161.385 208.179 170.468 1.00 59.01  ? 185 LYS A CB  1 
ATOM 7324 C CG  . LYS E 4 173 ? 160.997 209.504 169.840 1.00 59.01  ? 185 LYS A CG  1 
ATOM 7325 C CD  . LYS E 4 173 ? 159.900 210.185 170.637 1.00 59.01  ? 185 LYS A CD  1 
ATOM 7326 C CE  . LYS E 4 173 ? 158.678 209.291 170.759 1.00 59.01  ? 185 LYS A CE  1 
ATOM 7327 N NZ  . LYS E 4 173 ? 158.156 208.883 169.426 1.00 59.01  ? 185 LYS A NZ  1 
ATOM 7328 N N   . LEU E 4 174 ? 164.206 206.748 169.918 1.00 59.27  ? 186 LEU A N   1 
ATOM 7329 C CA  . LEU E 4 174 ? 165.625 206.805 169.586 1.00 59.27  ? 186 LEU A CA  1 
ATOM 7330 C C   . LEU E 4 174 ? 165.973 205.833 168.465 1.00 59.27  ? 186 LEU A C   1 
ATOM 7331 O O   . LEU E 4 174 ? 166.756 206.168 167.570 1.00 59.27  ? 186 LEU A O   1 
ATOM 7332 C CB  . LEU E 4 174 ? 166.472 206.518 170.824 1.00 59.27  ? 186 LEU A CB  1 
ATOM 7333 C CG  . LEU E 4 174 ? 167.962 206.848 170.706 1.00 59.27  ? 186 LEU A CG  1 
ATOM 7334 C CD1 . LEU E 4 174 ? 168.195 208.047 169.798 1.00 59.27  ? 186 LEU A CD1 1 
ATOM 7335 C CD2 . LEU E 4 174 ? 168.561 207.099 172.073 1.00 59.27  ? 186 LEU A CD2 1 
ATOM 7336 N N   . ILE E 4 175 ? 165.409 204.622 168.494 1.00 55.88  ? 187 ILE A N   1 
ATOM 7337 C CA  . ILE E 4 175 ? 165.736 203.640 167.463 1.00 55.88  ? 187 ILE A CA  1 
ATOM 7338 C C   . ILE E 4 175 ? 165.110 204.044 166.135 1.00 55.88  ? 187 ILE A C   1 
ATOM 7339 O O   . ILE E 4 175 ? 165.517 203.574 165.067 1.00 55.88  ? 187 ILE A O   1 
ATOM 7340 C CB  . ILE E 4 175 ? 165.297 202.228 167.890 1.00 55.88  ? 187 ILE A CB  1 
ATOM 7341 C CG1 . ILE E 4 175 ? 166.144 201.175 167.178 1.00 55.88  ? 187 ILE A CG1 1 
ATOM 7342 C CG2 . ILE E 4 175 ? 163.853 201.987 167.529 1.00 55.88  ? 187 ILE A CG2 1 
ATOM 7343 C CD1 . ILE E 4 175 ? 167.624 201.470 167.199 1.00 55.88  ? 187 ILE A CD1 1 
ATOM 7344 N N   . GLU E 4 176 ? 164.106 204.922 166.181 1.00 62.10  ? 188 GLU A N   1 
ATOM 7345 C CA  . GLU E 4 176 ? 163.525 205.465 164.961 1.00 62.10  ? 188 GLU A CA  1 
ATOM 7346 C C   . GLU E 4 176 ? 164.327 206.696 164.553 1.00 62.10  ? 188 GLU A C   1 
ATOM 7347 O O   . GLU E 4 176 ? 163.779 207.785 164.358 1.00 62.10  ? 188 GLU A O   1 
ATOM 7348 C CB  . GLU E 4 176 ? 162.038 205.782 165.162 1.00 62.10  ? 188 GLU A CB  1 
ATOM 7349 C CG  . GLU E 4 176 ? 161.266 206.145 163.899 1.00 62.10  ? 188 GLU A CG  1 
ATOM 7350 C CD  . GLU E 4 176 ? 160.891 207.611 163.843 1.00 62.10  ? 188 GLU A CD  1 
ATOM 7351 O OE1 . GLU E 4 176 ? 160.370 208.055 162.799 1.00 62.10  ? 188 GLU A OE1 1 
ATOM 7352 O OE2 . GLU E 4 176 ? 161.110 208.320 164.847 1.00 62.10  ? 188 GLU A OE2 1 
ATOM 7353 N N   . LYS E 4 177 ? 165.641 206.530 164.454 1.00 66.87  ? 189 LYS A N   1 
ATOM 7354 C CA  . LYS E 4 177 ? 166.552 207.536 163.924 1.00 66.87  ? 189 LYS A CA  1 
ATOM 7355 C C   . LYS E 4 177 ? 167.375 206.927 162.803 1.00 66.87  ? 189 LYS A C   1 
ATOM 7356 O O   . LYS E 4 177 ? 168.468 207.384 162.462 1.00 66.87  ? 189 LYS A O   1 
ATOM 7357 C CB  . LYS E 4 177 ? 167.441 208.107 165.023 1.00 66.87  ? 189 LYS A CB  1 
ATOM 7358 C CG  . LYS E 4 177 ? 166.693 208.966 166.030 1.00 66.87  ? 189 LYS A CG  1 
ATOM 7359 C CD  . LYS E 4 177 ? 165.985 210.127 165.353 1.00 66.87  ? 189 LYS A CD  1 
ATOM 7360 C CE  . LYS E 4 177 ? 166.014 211.375 166.221 1.00 66.87  ? 189 LYS A CE  1 
ATOM 7361 N NZ  . LYS E 4 177 ? 167.380 211.671 166.731 1.00 66.87  ? 189 LYS A NZ  1 
ATOM 7362 N N   . GLU E 4 178 ? 166.836 205.854 162.223 1.00 67.64  ? 190 GLU A N   1 
ATOM 7363 C CA  . GLU E 4 178 ? 167.449 205.209 161.069 1.00 67.64  ? 190 GLU A CA  1 
ATOM 7364 C C   . GLU E 4 178 ? 167.496 206.163 159.882 1.00 67.64  ? 190 GLU A C   1 
ATOM 7365 O O   . GLU E 4 178 ? 168.380 206.065 159.024 1.00 67.64  ? 190 GLU A O   1 
ATOM 7366 C CB  . GLU E 4 178 ? 166.664 203.945 160.707 1.00 67.64  ? 190 GLU A CB  1 
ATOM 7367 C CG  . GLU E 4 178 ? 166.144 203.176 161.910 1.00 67.64  ? 190 GLU A CG  1 
ATOM 7368 C CD  . GLU E 4 178 ? 165.484 201.866 161.532 1.00 67.64  ? 190 GLU A CD  1 
ATOM 7369 O OE1 . GLU E 4 178 ? 164.335 201.630 161.961 1.00 67.64  ? 190 GLU A OE1 1 
ATOM 7370 O OE2 . GLU E 4 178 ? 166.115 201.071 160.809 1.00 67.64  ? 190 GLU A OE2 1 
ATOM 7371 N N   . ARG E 4 179 ? 166.539 207.088 159.821 1.00 81.01  ? 191 ARG A N   1 
ATOM 7372 C CA  . ARG E 4 179 ? 166.367 207.977 158.681 1.00 81.01  ? 191 ARG A CA  1 
ATOM 7373 C C   . ARG E 4 179 ? 167.616 208.800 158.390 1.00 81.01  ? 191 ARG A C   1 
ATOM 7374 O O   . ARG E 4 179 ? 168.278 208.592 157.368 1.00 81.01  ? 191 ARG A O   1 
ATOM 7375 C CB  . ARG E 4 179 ? 165.181 208.907 158.941 1.00 81.01  ? 191 ARG A CB  1 
ATOM 7376 C CG  . ARG E 4 179 ? 164.862 209.870 157.817 1.00 81.01  ? 191 ARG A CG  1 
ATOM 7377 C CD  . ARG E 4 179 ? 163.597 210.686 158.093 1.00 81.01  ? 191 ARG A CD  1 
ATOM 7378 N NE  . ARG E 4 179 ? 162.531 209.920 158.733 1.00 81.01  ? 191 ARG A NE  1 
ATOM 7379 C CZ  . ARG E 4 179 ? 162.302 209.894 160.040 1.00 81.01  ? 191 ARG A CZ  1 
ATOM 7380 N NH1 . ARG E 4 179 ? 163.053 210.578 160.888 1.00 81.01  ? 191 ARG A NH1 1 
ATOM 7381 N NH2 . ARG E 4 179 ? 161.295 209.161 160.508 1.00 81.01  ? 191 ARG A NH2 1 
ATOM 7382 N N   . ASN E 4 180 ? 167.952 209.726 159.286 1.00 97.98  ? 192 ASN A N   1 
ATOM 7383 C CA  . ASN E 4 180 ? 169.138 210.559 159.124 1.00 97.98  ? 192 ASN A CA  1 
ATOM 7384 C C   . ASN E 4 180 ? 169.977 210.565 160.394 1.00 97.98  ? 192 ASN A C   1 
ATOM 7385 O O   . ASN E 4 180 ? 171.208 210.639 160.332 1.00 97.98  ? 192 ASN A O   1 
ATOM 7386 C CB  . ASN E 4 180 ? 168.757 211.995 158.749 1.00 97.98  ? 192 ASN A CB  1 
ATOM 7387 C CG  . ASN E 4 180 ? 167.651 212.064 157.713 1.00 97.98  ? 192 ASN A CG  1 
ATOM 7388 O OD1 . ASN E 4 180 ? 167.594 211.252 156.790 1.00 97.98  ? 192 ASN A OD1 1 
ATOM 7389 N ND2 . ASN E 4 180 ? 166.764 213.040 157.861 1.00 97.98  ? 192 ASN A ND2 1 
ATOM 7390 N N   . GLY E 4 181 ? 169.311 210.497 161.546 1.00 102.41 ? 193 GLY A N   1 
ATOM 7391 C CA  . GLY E 4 181 ? 169.956 210.683 162.830 1.00 102.41 ? 193 GLY A CA  1 
ATOM 7392 C C   . GLY E 4 181 ? 171.148 209.787 163.088 1.00 102.41 ? 193 GLY A C   1 
ATOM 7393 O O   . GLY E 4 181 ? 171.002 208.578 163.290 1.00 102.41 ? 193 GLY A O   1 
ATOM 7394 N N   . GLU E 4 182 ? 172.339 210.381 163.081 1.00 119.81 ? 194 GLU A N   1 
ATOM 7395 C CA  . GLU E 4 182 ? 173.556 209.668 163.445 1.00 119.81 ? 194 GLU A CA  1 
ATOM 7396 C C   . GLU E 4 182 ? 173.801 209.826 164.939 1.00 119.81 ? 194 GLU A C   1 
ATOM 7397 O O   . GLU E 4 182 ? 173.046 210.529 165.619 1.00 119.81 ? 194 GLU A O   1 
ATOM 7398 C CB  . GLU E 4 182 ? 174.748 210.184 162.632 1.00 119.81 ? 194 GLU A CB  1 
ATOM 7399 C CG  . GLU E 4 182 ? 175.470 211.404 163.215 1.00 119.81 ? 194 GLU A CG  1 
ATOM 7400 C CD  . GLU E 4 182 ? 174.637 212.681 163.207 1.00 119.81 ? 194 GLU A CD  1 
ATOM 7401 O OE1 . GLU E 4 182 ? 175.200 213.747 163.533 1.00 119.81 ? 194 GLU A OE1 1 
ATOM 7402 O OE2 . GLU E 4 182 ? 173.437 212.636 162.861 1.00 119.81 ? 194 GLU A OE2 1 
ATOM 7403 N N   . THR E 4 183 ? 174.853 209.190 165.452 1.00 114.70 ? 195 THR A N   1 
ATOM 7404 C CA  . THR E 4 183 ? 175.170 209.198 166.880 1.00 114.70 ? 195 THR A CA  1 
ATOM 7405 C C   . THR E 4 183 ? 173.952 208.792 167.706 1.00 114.70 ? 195 THR A C   1 
ATOM 7406 O O   . THR E 4 183 ? 173.420 209.565 168.506 1.00 114.70 ? 195 THR A O   1 
ATOM 7407 C CB  . THR E 4 183 ? 175.712 210.559 167.327 1.00 114.70 ? 195 THR A CB  1 
ATOM 7408 O OG1 . THR E 4 183 ? 174.755 211.586 167.040 1.00 114.70 ? 195 THR A OG1 1 
ATOM 7409 C CG2 . THR E 4 183 ? 177.017 210.873 166.611 1.00 114.70 ? 195 THR A CG2 1 
ATOM 7410 N N   . ILE E 4 184 ? 173.501 207.555 167.488 1.00 94.80  ? 196 ILE A N   1 
ATOM 7411 C CA  . ILE E 4 184 ? 172.371 207.017 168.243 1.00 94.80  ? 196 ILE A CA  1 
ATOM 7412 C C   . ILE E 4 184 ? 172.724 206.936 169.723 1.00 94.80  ? 196 ILE A C   1 
ATOM 7413 O O   . ILE E 4 184 ? 171.848 206.914 170.595 1.00 94.80  ? 196 ILE A O   1 
ATOM 7414 C CB  . ILE E 4 184 ? 171.959 205.643 167.685 1.00 94.80  ? 196 ILE A CB  1 
ATOM 7415 C CG1 . ILE E 4 184 ? 171.741 205.727 166.173 1.00 94.80  ? 196 ILE A CG1 1 
ATOM 7416 C CG2 . ILE E 4 184 ? 170.689 205.144 168.353 1.00 94.80  ? 196 ILE A CG2 1 
ATOM 7417 C CD1 . ILE E 4 184 ? 171.325 204.414 165.539 1.00 94.80  ? 196 ILE A CD1 1 
ATOM 7418 N N   . ASN E 4 185 ? 174.026 206.904 170.021 1.00 87.09  ? 197 ASN A N   1 
ATOM 7419 C CA  . ASN E 4 185 ? 174.536 206.730 171.375 1.00 87.09  ? 197 ASN A CA  1 
ATOM 7420 C C   . ASN E 4 185 ? 174.054 205.390 171.912 1.00 87.09  ? 197 ASN A C   1 
ATOM 7421 O O   . ASN E 4 185 ? 173.359 205.324 172.930 1.00 87.09  ? 197 ASN A O   1 
ATOM 7422 C CB  . ASN E 4 185 ? 174.115 207.890 172.282 1.00 87.09  ? 197 ASN A CB  1 
ATOM 7423 C CG  . ASN E 4 185 ? 175.146 208.198 173.349 1.00 87.09  ? 197 ASN A CG  1 
ATOM 7424 O OD1 . ASN E 4 185 ? 175.905 207.322 173.766 1.00 87.09  ? 197 ASN A OD1 1 
ATOM 7425 N ND2 . ASN E 4 185 ? 175.176 209.446 173.800 1.00 87.09  ? 197 ASN A ND2 1 
ATOM 7426 N N   . THR E 4 186 ? 174.421 204.324 171.201 1.00 71.43  ? 198 THR A N   1 
ATOM 7427 C CA  . THR E 4 186 ? 174.016 202.947 171.461 1.00 71.43  ? 198 THR A CA  1 
ATOM 7428 C C   . THR E 4 186 ? 174.064 202.573 172.940 1.00 71.43  ? 198 THR A C   1 
ATOM 7429 O O   . THR E 4 186 ? 173.193 201.842 173.423 1.00 71.43  ? 198 THR A O   1 
ATOM 7430 C CB  . THR E 4 186 ? 174.902 202.006 170.637 1.00 71.43  ? 198 THR A CB  1 
ATOM 7431 O OG1 . THR E 4 186 ? 174.460 202.008 169.274 1.00 71.43  ? 198 THR A OG1 1 
ATOM 7432 C CG2 . THR E 4 186 ? 174.849 200.589 171.166 1.00 71.43  ? 198 THR A CG2 1 
ATOM 7433 N N   . ARG E 4 187 ? 175.061 203.084 173.664 1.00 68.93  ? 199 ARG A N   1 
ATOM 7434 C CA  . ARG E 4 187 ? 175.312 202.700 175.050 1.00 68.93  ? 199 ARG A CA  1 
ATOM 7435 C C   . ARG E 4 187 ? 174.063 202.753 175.922 1.00 68.93  ? 199 ARG A C   1 
ATOM 7436 O O   . ARG E 4 187 ? 173.812 201.826 176.698 1.00 68.93  ? 199 ARG A O   1 
ATOM 7437 C CB  . ARG E 4 187 ? 176.397 203.592 175.656 1.00 68.93  ? 199 ARG A CB  1 
ATOM 7438 C CG  . ARG E 4 187 ? 176.959 203.065 176.967 1.00 68.93  ? 199 ARG A CG  1 
ATOM 7439 C CD  . ARG E 4 187 ? 178.150 202.149 176.730 1.00 68.93  ? 199 ARG A CD  1 
ATOM 7440 N NE  . ARG E 4 187 ? 178.959 202.577 175.594 1.00 68.93  ? 199 ARG A NE  1 
ATOM 7441 C CZ  . ARG E 4 187 ? 179.777 203.621 175.605 1.00 68.93  ? 199 ARG A CZ  1 
ATOM 7442 N NH1 . ARG E 4 187 ? 179.940 204.362 176.689 1.00 68.93  ? 199 ARG A NH1 1 
ATOM 7443 N NH2 . ARG E 4 187 ? 180.450 203.928 174.500 1.00 68.93  ? 199 ARG A NH2 1 
ATOM 7444 N N   . LEU E 4 188 ? 173.277 203.826 175.814 1.00 69.67  ? 200 LEU A N   1 
ATOM 7445 C CA  . LEU E 4 188 ? 172.045 203.924 176.588 1.00 69.67  ? 200 LEU A CA  1 
ATOM 7446 C C   . LEU E 4 188 ? 171.057 202.825 176.213 1.00 69.67  ? 200 LEU A C   1 
ATOM 7447 O O   . LEU E 4 188 ? 170.429 202.215 177.085 1.00 69.67  ? 200 LEU A O   1 
ATOM 7448 C CB  . LEU E 4 188 ? 171.399 205.305 176.412 1.00 69.67  ? 200 LEU A CB  1 
ATOM 7449 C CG  . LEU E 4 188 ? 172.196 206.567 176.755 1.00 69.67  ? 200 LEU A CG  1 
ATOM 7450 C CD1 . LEU E 4 188 ? 173.140 206.967 175.649 1.00 69.67  ? 200 LEU A CD1 1 
ATOM 7451 C CD2 . LEU E 4 188 ? 171.252 207.716 177.073 1.00 69.67  ? 200 LEU A CD2 1 
ATOM 7452 N N   . ILE E 4 189 ? 170.907 202.559 174.914 1.00 57.53  ? 201 ILE A N   1 
ATOM 7453 C CA  . ILE E 4 189 ? 169.962 201.530 174.493 1.00 57.53  ? 201 ILE A CA  1 
ATOM 7454 C C   . ILE E 4 189 ? 170.462 200.145 174.874 1.00 57.53  ? 201 ILE A C   1 
ATOM 7455 O O   . ILE E 4 189 ? 169.675 199.289 175.294 1.00 57.53  ? 201 ILE A O   1 
ATOM 7456 C CB  . ILE E 4 189 ? 169.679 201.631 172.985 1.00 57.53  ? 201 ILE A CB  1 
ATOM 7457 C CG1 . ILE E 4 189 ? 169.086 202.997 172.649 1.00 57.53  ? 201 ILE A CG1 1 
ATOM 7458 C CG2 . ILE E 4 189 ? 168.705 200.557 172.570 1.00 57.53  ? 201 ILE A CG2 1 
ATOM 7459 C CD1 . ILE E 4 189 ? 168.769 203.178 171.183 1.00 57.53  ? 201 ILE A CD1 1 
ATOM 7460 N N   . SER E 4 190 ? 171.768 199.899 174.743 1.00 58.04  ? 202 SER A N   1 
ATOM 7461 C CA  . SER E 4 190 ? 172.327 198.603 175.117 1.00 58.04  ? 202 SER A CA  1 
ATOM 7462 C C   . SER E 4 190 ? 172.062 198.294 176.585 1.00 58.04  ? 202 SER A C   1 
ATOM 7463 O O   . SER E 4 190 ? 171.860 197.137 176.966 1.00 58.04  ? 202 SER A O   1 
ATOM 7464 C CB  . SER E 4 190 ? 173.827 198.569 174.825 1.00 58.04  ? 202 SER A CB  1 
ATOM 7465 O OG  . SER E 4 190 ? 174.073 198.589 173.432 1.00 58.04  ? 202 SER A OG  1 
ATOM 7466 N N   . GLY E 4 191 ? 172.069 199.328 177.426 1.00 54.69  ? 203 GLY A N   1 
ATOM 7467 C CA  . GLY E 4 191 ? 171.725 199.126 178.823 1.00 54.69  ? 203 GLY A CA  1 
ATOM 7468 C C   . GLY E 4 191 ? 170.279 198.708 179.007 1.00 54.69  ? 203 GLY A C   1 
ATOM 7469 O O   . GLY E 4 191 ? 169.968 197.849 179.835 1.00 54.69  ? 203 GLY A O   1 
ATOM 7470 N N   . VAL E 4 192 ? 169.374 199.314 178.236 1.00 53.79  ? 204 VAL A N   1 
ATOM 7471 C CA  . VAL E 4 192 ? 167.948 199.031 178.389 1.00 53.79  ? 204 VAL A CA  1 
ATOM 7472 C C   . VAL E 4 192 ? 167.633 197.604 177.958 1.00 53.79  ? 204 VAL A C   1 
ATOM 7473 O O   . VAL E 4 192 ? 166.970 196.850 178.679 1.00 53.79  ? 204 VAL A O   1 
ATOM 7474 C CB  . VAL E 4 192 ? 167.108 200.050 177.603 1.00 53.79  ? 204 VAL A CB  1 
ATOM 7475 C CG1 . VAL E 4 192 ? 165.636 199.747 177.761 1.00 53.79  ? 204 VAL A CG1 1 
ATOM 7476 C CG2 . VAL E 4 192 ? 167.410 201.454 178.081 1.00 53.79  ? 204 VAL A CG2 1 
ATOM 7477 N N   . VAL E 4 193 ? 168.109 197.208 176.774 1.00 50.77  ? 205 VAL A N   1 
ATOM 7478 C CA  . VAL E 4 193 ? 167.766 195.888 176.244 1.00 50.77  ? 205 VAL A CA  1 
ATOM 7479 C C   . VAL E 4 193 ? 168.361 194.794 177.121 1.00 50.77  ? 205 VAL A C   1 
ATOM 7480 O O   . VAL E 4 193 ? 167.704 193.795 177.434 1.00 50.77  ? 205 VAL A O   1 
ATOM 7481 C CB  . VAL E 4 193 ? 168.223 195.751 174.781 1.00 50.77  ? 205 VAL A CB  1 
ATOM 7482 C CG1 . VAL E 4 193 ? 169.653 196.221 174.614 1.00 50.77  ? 205 VAL A CG1 1 
ATOM 7483 C CG2 . VAL E 4 193 ? 168.077 194.314 174.317 1.00 50.77  ? 205 VAL A CG2 1 
ATOM 7484 N N   . GLN E 4 194 ? 169.617 194.971 177.536 1.00 49.65  ? 206 GLN A N   1 
ATOM 7485 C CA  . GLN E 4 194 ? 170.240 194.009 178.435 1.00 49.65  ? 206 GLN A CA  1 
ATOM 7486 C C   . GLN E 4 194 ? 169.546 193.971 179.788 1.00 49.65  ? 206 GLN A C   1 
ATOM 7487 O O   . GLN E 4 194 ? 169.549 192.925 180.443 1.00 49.65  ? 206 GLN A O   1 
ATOM 7488 C CB  . GLN E 4 194 ? 171.727 194.336 178.595 1.00 49.65  ? 206 GLN A CB  1 
ATOM 7489 C CG  . GLN E 4 194 ? 172.529 193.338 179.416 1.00 49.65  ? 206 GLN A CG  1 
ATOM 7490 C CD  . GLN E 4 194 ? 172.477 193.621 180.900 1.00 49.65  ? 206 GLN A CD  1 
ATOM 7491 O OE1 . GLN E 4 194 ? 172.196 194.743 181.318 1.00 49.65  ? 206 GLN A OE1 1 
ATOM 7492 N NE2 . GLN E 4 194 ? 172.747 192.603 181.708 1.00 49.65  ? 206 GLN A NE2 1 
ATOM 7493 N N   . SER E 4 195 ? 168.945 195.083 180.215 1.00 53.14  ? 207 SER A N   1 
ATOM 7494 C CA  . SER E 4 195 ? 168.199 195.084 181.468 1.00 53.14  ? 207 SER A CA  1 
ATOM 7495 C C   . SER E 4 195 ? 166.972 194.186 181.376 1.00 53.14  ? 207 SER A C   1 
ATOM 7496 O O   . SER E 4 195 ? 166.715 193.376 182.272 1.00 53.14  ? 207 SER A O   1 
ATOM 7497 C CB  . SER E 4 195 ? 167.796 196.511 181.836 1.00 53.14  ? 207 SER A CB  1 
ATOM 7498 O OG  . SER E 4 195 ? 167.269 196.566 183.149 1.00 53.14  ? 207 SER A OG  1 
ATOM 7499 N N   . TYR E 4 196 ? 166.205 194.309 180.290 1.00 52.61  ? 208 TYR A N   1 
ATOM 7500 C CA  . TYR E 4 196 ? 165.003 193.494 180.149 1.00 52.61  ? 208 TYR A CA  1 
ATOM 7501 C C   . TYR E 4 196 ? 165.348 192.013 180.087 1.00 52.61  ? 208 TYR A C   1 
ATOM 7502 O O   . TYR E 4 196 ? 164.650 191.181 180.676 1.00 52.61  ? 208 TYR A O   1 
ATOM 7503 C CB  . TYR E 4 196 ? 164.222 193.910 178.904 1.00 52.61  ? 208 TYR A CB  1 
ATOM 7504 C CG  . TYR E 4 196 ? 163.415 195.171 179.082 1.00 52.61  ? 208 TYR A CG  1 
ATOM 7505 C CD1 . TYR E 4 196 ? 162.113 195.125 179.545 1.00 52.61  ? 208 TYR A CD1 1 
ATOM 7506 C CD2 . TYR E 4 196 ? 163.950 196.408 178.766 1.00 52.61  ? 208 TYR A CD2 1 
ATOM 7507 C CE1 . TYR E 4 196 ? 161.375 196.277 179.705 1.00 52.61  ? 208 TYR A CE1 1 
ATOM 7508 C CE2 . TYR E 4 196 ? 163.220 197.561 178.920 1.00 52.61  ? 208 TYR A CE2 1 
ATOM 7509 C CZ  . TYR E 4 196 ? 161.934 197.491 179.387 1.00 52.61  ? 208 TYR A CZ  1 
ATOM 7510 O OH  . TYR E 4 196 ? 161.204 198.644 179.541 1.00 52.61  ? 208 TYR A OH  1 
ATOM 7511 N N   . VAL E 4 197 ? 166.421 191.666 179.374 1.00 50.80  ? 209 VAL A N   1 
ATOM 7512 C CA  . VAL E 4 197 ? 166.863 190.275 179.310 1.00 50.80  ? 209 VAL A CA  1 
ATOM 7513 C C   . VAL E 4 197 ? 167.268 189.795 180.697 1.00 50.80  ? 209 VAL A C   1 
ATOM 7514 O O   . VAL E 4 197 ? 166.927 188.685 181.120 1.00 50.80  ? 209 VAL A O   1 
ATOM 7515 C CB  . VAL E 4 197 ? 168.018 190.124 178.307 1.00 50.80  ? 209 VAL A CB  1 
ATOM 7516 C CG1 . VAL E 4 197 ? 168.530 188.697 178.299 1.00 50.80  ? 209 VAL A CG1 1 
ATOM 7517 C CG2 . VAL E 4 197 ? 167.572 190.551 176.922 1.00 50.80  ? 209 VAL A CG2 1 
ATOM 7518 N N   . GLU E 4 198 ? 168.004 190.638 181.426 1.00 48.48  ? 210 GLU A N   1 
ATOM 7519 C CA  . GLU E 4 198 ? 168.459 190.266 182.762 1.00 48.48  ? 210 GLU A CA  1 
ATOM 7520 C C   . GLU E 4 198 ? 167.283 190.092 183.713 1.00 48.48  ? 210 GLU A C   1 
ATOM 7521 O O   . GLU E 4 198 ? 167.276 189.180 184.546 1.00 48.48  ? 210 GLU A O   1 
ATOM 7522 C CB  . GLU E 4 198 ? 169.431 191.316 183.297 1.00 48.48  ? 210 GLU A CB  1 
ATOM 7523 C CG  . GLU E 4 198 ? 169.698 191.190 184.776 1.00 48.48  ? 210 GLU A CG  1 
ATOM 7524 C CD  . GLU E 4 198 ? 170.242 189.825 185.132 1.00 48.48  ? 210 GLU A CD  1 
ATOM 7525 O OE1 . GLU E 4 198 ? 171.231 189.402 184.501 1.00 48.48  ? 210 GLU A OE1 1 
ATOM 7526 O OE2 . GLU E 4 198 ? 169.676 189.169 186.029 1.00 48.48  ? 210 GLU A OE2 1 
ATOM 7527 N N   . LEU E 4 199 ? 166.267 190.946 183.588 1.00 51.86  ? 211 LEU A N   1 
ATOM 7528 C CA  . LEU E 4 199 ? 165.046 190.853 184.390 1.00 51.86  ? 211 LEU A CA  1 
ATOM 7529 C C   . LEU E 4 199 ? 164.222 189.632 184.074 1.00 51.86  ? 211 LEU A C   1 
ATOM 7530 O O   . LEU E 4 199 ? 163.097 189.561 184.584 1.00 51.86  ? 211 LEU A O   1 
ATOM 7531 C CB  . LEU E 4 199 ? 164.189 192.106 184.207 1.00 51.86  ? 211 LEU A CB  1 
ATOM 7532 C CG  . LEU E 4 199 ? 164.335 193.215 185.247 1.00 51.86  ? 211 LEU A CG  1 
ATOM 7533 C CD1 . LEU E 4 199 ? 164.098 192.646 186.628 1.00 51.86  ? 211 LEU A CD1 1 
ATOM 7534 C CD2 . LEU E 4 199 ? 165.697 193.868 185.170 1.00 51.86  ? 211 LEU A CD2 1 
ATOM 7535 N N   . GLY E 4 200 ? 164.729 188.716 183.252 1.00 67.04  ? 212 GLY A N   1 
ATOM 7536 C CA  . GLY E 4 200 ? 164.049 187.469 182.967 1.00 67.04  ? 212 GLY A CA  1 
ATOM 7537 C C   . GLY E 4 200 ? 163.566 186.794 184.229 1.00 67.04  ? 212 GLY A C   1 
ATOM 7538 O O   . GLY E 4 200 ? 164.271 186.778 185.242 1.00 67.04  ? 212 GLY A O   1 
ATOM 7539 N N   . LEU E 4 201 ? 162.359 186.242 184.181 1.00 89.32  ? 213 LEU A N   1 
ATOM 7540 C CA  . LEU E 4 201 ? 161.657 185.785 185.369 1.00 89.32  ? 213 LEU A CA  1 
ATOM 7541 C C   . LEU E 4 201 ? 162.428 184.661 186.042 1.00 89.32  ? 213 LEU A C   1 
ATOM 7542 O O   . LEU E 4 201 ? 162.394 183.511 185.592 1.00 89.32  ? 213 LEU A O   1 
ATOM 7543 C CB  . LEU E 4 201 ? 160.240 185.315 185.021 1.00 89.32  ? 213 LEU A CB  1 
ATOM 7544 C CG  . LEU E 4 201 ? 159.160 185.545 186.081 1.00 89.32  ? 213 LEU A CG  1 
ATOM 7545 C CD1 . LEU E 4 201 ? 159.198 186.975 186.598 1.00 89.32  ? 213 LEU A CD1 1 
ATOM 7546 C CD2 . LEU E 4 201 ? 157.788 185.214 185.519 1.00 89.32  ? 213 LEU A CD2 1 
ATOM 7547 N N   . ASN E 4 202 ? 163.124 185.004 187.125 1.00 93.59  ? 214 ASN A N   1 
ATOM 7548 C CA  . ASN E 4 202 ? 163.736 184.007 187.992 1.00 93.59  ? 214 ASN A CA  1 
ATOM 7549 C C   . ASN E 4 202 ? 162.826 183.614 189.144 1.00 93.59  ? 214 ASN A C   1 
ATOM 7550 O O   . ASN E 4 202 ? 163.227 182.803 189.986 1.00 93.59  ? 214 ASN A O   1 
ATOM 7551 C CB  . ASN E 4 202 ? 165.066 184.530 188.536 1.00 93.59  ? 214 ASN A CB  1 
ATOM 7552 C CG  . ASN E 4 202 ? 165.754 185.476 187.575 1.00 93.59  ? 214 ASN A CG  1 
ATOM 7553 O OD1 . ASN E 4 202 ? 166.286 185.057 186.547 1.00 93.59  ? 214 ASN A OD1 1 
ATOM 7554 N ND2 . ASN E 4 202 ? 165.750 186.762 187.906 1.00 93.59  ? 214 ASN A ND2 1 
ATOM 7555 N N   . GLU E 4 203 ? 161.620 184.175 189.194 1.00 102.36 ? 215 GLU A N   1 
ATOM 7556 C CA  . GLU E 4 203 ? 160.647 183.873 190.236 1.00 102.36 ? 215 GLU A CA  1 
ATOM 7557 C C   . GLU E 4 203 ? 160.301 182.392 190.170 1.00 102.36 ? 215 GLU A C   1 
ATOM 7558 O O   . GLU E 4 203 ? 159.910 181.888 189.112 1.00 102.36 ? 215 GLU A O   1 
ATOM 7559 C CB  . GLU E 4 203 ? 159.400 184.732 190.054 1.00 102.36 ? 215 GLU A CB  1 
ATOM 7560 C CG  . GLU E 4 203 ? 159.636 186.214 190.254 1.00 102.36 ? 215 GLU A CG  1 
ATOM 7561 C CD  . GLU E 4 203 ? 158.379 187.034 190.057 1.00 102.36 ? 215 GLU A CD  1 
ATOM 7562 O OE1 . GLU E 4 203 ? 157.344 186.453 189.672 1.00 102.36 ? 215 GLU A OE1 1 
ATOM 7563 O OE2 . GLU E 4 203 ? 158.427 188.262 190.279 1.00 102.36 ? 215 GLU A OE2 1 
ATOM 7564 N N   . ASP E 4 204 ? 160.466 181.695 191.295 1.00 114.62 ? 216 ASP A N   1 
ATOM 7565 C CA  . ASP E 4 204 ? 160.119 180.283 191.418 1.00 114.62 ? 216 ASP A CA  1 
ATOM 7566 C C   . ASP E 4 204 ? 160.991 179.432 190.504 1.00 114.62 ? 216 ASP A C   1 
ATOM 7567 O O   . ASP E 4 204 ? 162.158 179.765 190.269 1.00 114.62 ? 216 ASP A O   1 
ATOM 7568 C CB  . ASP E 4 204 ? 158.635 180.057 191.112 1.00 114.62 ? 216 ASP A CB  1 
ATOM 7569 C CG  . ASP E 4 204 ? 157.743 180.370 192.295 1.00 114.62 ? 216 ASP A CG  1 
ATOM 7570 O OD1 . ASP E 4 204 ? 158.087 179.962 193.424 1.00 114.62 ? 216 ASP A OD1 1 
ATOM 7571 O OD2 . ASP E 4 204 ? 156.701 181.028 192.097 1.00 114.62 ? 216 ASP A OD2 1 
ATOM 7572 N N   . ASP E 4 205 ? 160.420 178.357 189.964 1.00 119.34 ? 217 ASP A N   1 
ATOM 7573 C CA  . ASP E 4 205 ? 161.146 177.357 189.166 1.00 119.34 ? 217 ASP A CA  1 
ATOM 7574 C C   . ASP E 4 205 ? 162.379 176.956 189.972 1.00 119.34 ? 217 ASP A C   1 
ATOM 7575 O O   . ASP E 4 205 ? 162.238 176.569 191.143 1.00 119.34 ? 217 ASP A O   1 
ATOM 7576 C CB  . ASP E 4 205 ? 161.424 177.898 187.767 1.00 119.34 ? 217 ASP A CB  1 
ATOM 7577 C CG  . ASP E 4 205 ? 160.308 178.779 187.245 1.00 119.34 ? 217 ASP A CG  1 
ATOM 7578 O OD1 . ASP E 4 205 ? 159.241 178.239 186.885 1.00 119.34 ? 217 ASP A OD1 1 
ATOM 7579 O OD2 . ASP E 4 205 ? 160.500 180.011 187.190 1.00 119.34 ? 217 ASP A OD2 1 
ATOM 7580 N N   . ALA E 4 206 ? 163.582 177.029 189.408 1.00 112.63 ? 218 ALA A N   1 
ATOM 7581 C CA  . ALA E 4 206 ? 164.809 176.789 190.154 1.00 112.63 ? 218 ALA A CA  1 
ATOM 7582 C C   . ALA E 4 206 ? 165.929 177.638 189.571 1.00 112.63 ? 218 ALA A C   1 
ATOM 7583 O O   . ALA E 4 206 ? 165.682 178.493 188.714 1.00 112.63 ? 218 ALA A O   1 
ATOM 7584 C CB  . ALA E 4 206 ? 165.182 175.306 190.129 1.00 112.63 ? 218 ALA A CB  1 
ATOM 7585 N N   . PHE E 4 207 ? 167.159 177.416 190.021 1.00 110.68 ? 219 PHE A N   1 
ATOM 7586 C CA  . PHE E 4 207 ? 168.310 178.120 189.460 1.00 110.68 ? 219 PHE A CA  1 
ATOM 7587 C C   . PHE E 4 207 ? 168.891 177.358 188.271 1.00 110.68 ? 219 PHE A C   1 
ATOM 7588 O O   . PHE E 4 207 ? 170.063 176.985 188.249 1.00 110.68 ? 219 PHE A O   1 
ATOM 7589 C CB  . PHE E 4 207 ? 169.362 178.349 190.539 1.00 110.68 ? 219 PHE A CB  1 
ATOM 7590 C CG  . PHE E 4 207 ? 170.431 179.329 190.145 1.00 110.68 ? 219 PHE A CG  1 
ATOM 7591 C CD1 . PHE E 4 207 ? 170.183 180.296 189.182 1.00 110.68 ? 219 PHE A CD1 1 
ATOM 7592 C CD2 . PHE E 4 207 ? 171.683 179.286 190.736 1.00 110.68 ? 219 PHE A CD2 1 
ATOM 7593 C CE1 . PHE E 4 207 ? 171.164 181.198 188.816 1.00 110.68 ? 219 PHE A CE1 1 
ATOM 7594 C CE2 . PHE E 4 207 ? 172.667 180.187 190.374 1.00 110.68 ? 219 PHE A CE2 1 
ATOM 7595 C CZ  . PHE E 4 207 ? 172.407 181.144 189.413 1.00 110.68 ? 219 PHE A CZ  1 
ATOM 7596 N N   . ALA E 4 208 ? 168.052 177.117 187.268 1.00 100.39 ? 220 ALA A N   1 
ATOM 7597 C CA  . ALA E 4 208 ? 168.466 176.385 186.078 1.00 100.39 ? 220 ALA A CA  1 
ATOM 7598 C C   . ALA E 4 208 ? 169.239 177.287 185.123 1.00 100.39 ? 220 ALA A C   1 
ATOM 7599 O O   . ALA E 4 208 ? 168.676 177.824 184.169 1.00 100.39 ? 220 ALA A O   1 
ATOM 7600 C CB  . ALA E 4 208 ? 167.256 175.785 185.380 1.00 100.39 ? 220 ALA A CB  1 
ATOM 7601 N N   . GLY E 4 210 ? 166.643 177.108 180.370 1.00 109.66 ? 222 GLY A N   1 
ATOM 7602 C CA  . GLY E 4 210 ? 167.505 177.632 179.328 1.00 109.66 ? 222 GLY A CA  1 
ATOM 7603 C C   . GLY E 4 210 ? 167.764 179.121 179.452 1.00 109.66 ? 222 GLY A C   1 
ATOM 7604 O O   . GLY E 4 210 ? 168.358 179.572 180.431 1.00 109.66 ? 222 GLY A O   1 
ATOM 7605 N N   . PRO E 4 211 ? 167.322 179.892 178.457 1.00 104.97 ? 223 PRO A N   1 
ATOM 7606 C CA  . PRO E 4 211 ? 167.519 181.346 178.508 1.00 104.97 ? 223 PRO A CA  1 
ATOM 7607 C C   . PRO E 4 211 ? 166.444 182.045 179.324 1.00 104.97 ? 223 PRO A C   1 
ATOM 7608 O O   . PRO E 4 211 ? 165.520 181.401 179.833 1.00 104.97 ? 223 PRO A O   1 
ATOM 7609 C CB  . PRO E 4 211 ? 167.468 181.766 177.031 1.00 104.97 ? 223 PRO A CB  1 
ATOM 7610 C CG  . PRO E 4 211 ? 167.083 180.517 176.244 1.00 104.97 ? 223 PRO A CG  1 
ATOM 7611 C CD  . PRO E 4 211 ? 166.645 179.475 177.221 1.00 104.97 ? 223 PRO A CD  1 
ATOM 7612 N N   . THR E 4 212 ? 166.555 183.367 179.452 1.00 82.97  ? 224 THR A N   1 
ATOM 7613 C CA  . THR E 4 212 ? 165.601 184.160 180.211 1.00 82.97  ? 224 THR A CA  1 
ATOM 7614 C C   . THR E 4 212 ? 164.898 185.225 179.384 1.00 82.97  ? 224 THR A C   1 
ATOM 7615 O O   . THR E 4 212 ? 164.581 186.291 179.923 1.00 82.97  ? 224 THR A O   1 
ATOM 7616 C CB  . THR E 4 212 ? 166.295 184.835 181.404 1.00 82.97  ? 224 THR A CB  1 
ATOM 7617 O OG1 . THR E 4 212 ? 167.626 185.212 181.031 1.00 82.97  ? 224 THR A OG1 1 
ATOM 7618 C CG2 . THR E 4 212 ? 166.357 183.885 182.589 1.00 82.97  ? 224 THR A CG2 1 
ATOM 7619 N N   . LEU E 4 213 ? 164.649 184.974 178.101 1.00 68.68  ? 225 LEU A N   1 
ATOM 7620 C CA  . LEU E 4 213 ? 164.048 185.958 177.210 1.00 68.68  ? 225 LEU A CA  1 
ATOM 7621 C C   . LEU E 4 213 ? 162.524 185.972 177.316 1.00 68.68  ? 225 LEU A C   1 
ATOM 7622 O O   . LEU E 4 213 ? 161.814 185.941 176.309 1.00 68.68  ? 225 LEU A O   1 
ATOM 7623 C CB  . LEU E 4 213 ? 164.569 185.693 175.786 1.00 68.68  ? 225 LEU A CB  1 
ATOM 7624 C CG  . LEU E 4 213 ? 164.239 184.516 174.844 1.00 68.68  ? 225 LEU A CG  1 
ATOM 7625 C CD1 . LEU E 4 213 ? 162.965 184.632 174.019 1.00 68.68  ? 225 LEU A CD1 1 
ATOM 7626 C CD2 . LEU E 4 213 ? 165.428 184.239 173.930 1.00 68.68  ? 225 LEU A CD2 1 
ATOM 7627 N N   . THR E 4 214 ? 162.007 186.087 178.539 1.00 67.77  ? 226 THR A N   1 
ATOM 7628 C CA  . THR E 4 214 ? 160.559 186.092 178.721 1.00 67.77  ? 226 THR A CA  1 
ATOM 7629 C C   . THR E 4 214 ? 160.036 187.489 179.044 1.00 67.77  ? 226 THR A C   1 
ATOM 7630 O O   . THR E 4 214 ? 158.856 187.783 178.831 1.00 67.77  ? 226 THR A O   1 
ATOM 7631 C CB  . THR E 4 214 ? 160.157 185.092 179.810 1.00 67.77  ? 226 THR A CB  1 
ATOM 7632 O OG1 . THR E 4 214 ? 158.757 184.808 179.703 1.00 67.77  ? 226 THR A OG1 1 
ATOM 7633 C CG2 . THR E 4 214 ? 160.455 185.642 181.196 1.00 67.77  ? 226 THR A CG2 1 
ATOM 7634 N N   . VAL E 4 215 ? 160.896 188.362 179.565 1.00 60.59  ? 227 VAL A N   1 
ATOM 7635 C CA  . VAL E 4 215 ? 160.496 189.733 179.861 1.00 60.59  ? 227 VAL A CA  1 
ATOM 7636 C C   . VAL E 4 215 ? 161.083 190.609 178.760 1.00 60.59  ? 227 VAL A C   1 
ATOM 7637 O O   . VAL E 4 215 ? 161.105 191.841 178.857 1.00 60.59  ? 227 VAL A O   1 
ATOM 7638 C CB  . VAL E 4 215 ? 160.958 190.160 181.269 1.00 60.59  ? 227 VAL A CB  1 
ATOM 7639 C CG1 . VAL E 4 215 ? 160.393 191.524 181.662 1.00 60.59  ? 227 VAL A CG1 1 
ATOM 7640 C CG2 . VAL E 4 215 ? 160.562 189.113 182.292 1.00 60.59  ? 227 VAL A CG2 1 
ATOM 7641 N N   . TYR E 4 216 ? 161.551 189.971 177.690 1.00 63.17  ? 228 TYR A N   1 
ATOM 7642 C CA  . TYR E 4 216 ? 162.079 190.684 176.533 1.00 63.17  ? 228 TYR A CA  1 
ATOM 7643 C C   . TYR E 4 216 ? 161.056 190.746 175.409 1.00 63.17  ? 228 TYR A C   1 
ATOM 7644 O O   . TYR E 4 216 ? 160.929 191.783 174.752 1.00 63.17  ? 228 TYR A O   1 
ATOM 7645 C CB  . TYR E 4 216 ? 163.375 190.015 176.058 1.00 63.17  ? 228 TYR A CB  1 
ATOM 7646 C CG  . TYR E 4 216 ? 164.085 190.730 174.932 1.00 63.17  ? 228 TYR A CG  1 
ATOM 7647 C CD1 . TYR E 4 216 ? 164.041 192.110 174.820 1.00 63.17  ? 228 TYR A CD1 1 
ATOM 7648 C CD2 . TYR E 4 216 ? 164.809 190.021 173.985 1.00 63.17  ? 228 TYR A CD2 1 
ATOM 7649 C CE1 . TYR E 4 216 ? 164.692 192.761 173.795 1.00 63.17  ? 228 TYR A CE1 1 
ATOM 7650 C CE2 . TYR E 4 216 ? 165.462 190.664 172.958 1.00 63.17  ? 228 TYR A CE2 1 
ATOM 7651 C CZ  . TYR E 4 216 ? 165.401 192.033 172.867 1.00 63.17  ? 228 TYR A CZ  1 
ATOM 7652 O OH  . TYR E 4 216 ? 166.053 192.678 171.842 1.00 63.17  ? 228 TYR A OH  1 
ATOM 7653 N N   . LYS E 4 217 ? 160.316 189.663 175.173 1.00 69.27  ? 229 LYS A N   1 
ATOM 7654 C CA  . LYS E 4 217 ? 159.308 189.627 174.121 1.00 69.27  ? 229 LYS A CA  1 
ATOM 7655 C C   . LYS E 4 217 ? 158.180 190.617 174.376 1.00 69.27  ? 229 LYS A C   1 
ATOM 7656 O O   . LYS E 4 217 ? 157.759 191.334 173.463 1.00 69.27  ? 229 LYS A O   1 
ATOM 7657 C CB  . LYS E 4 217 ? 158.732 188.217 173.978 1.00 69.27  ? 229 LYS A CB  1 
ATOM 7658 C CG  . LYS E 4 217 ? 159.752 187.150 173.636 1.00 69.27  ? 229 LYS A CG  1 
ATOM 7659 C CD  . LYS E 4 217 ? 159.154 186.130 172.685 1.00 69.27  ? 229 LYS A CD  1 
ATOM 7660 C CE  . LYS E 4 217 ? 160.233 185.371 171.940 1.00 69.27  ? 229 LYS A CE  1 
ATOM 7661 N NZ  . LYS E 4 217 ? 161.136 186.288 171.196 1.00 69.27  ? 229 LYS A NZ  1 
ATOM 7662 N N   . GLU E 4 218 ? 157.685 190.669 175.611 1.00 65.90  ? 230 GLU A N   1 
ATOM 7663 C CA  . GLU E 4 218 ? 156.482 191.440 175.898 1.00 65.90  ? 230 GLU A CA  1 
ATOM 7664 C C   . GLU E 4 218 ? 156.768 192.920 176.115 1.00 65.90  ? 230 GLU A C   1 
ATOM 7665 O O   . GLU E 4 218 ? 155.838 193.699 176.345 1.00 65.90  ? 230 GLU A O   1 
ATOM 7666 C CB  . GLU E 4 218 ? 155.756 190.876 177.122 1.00 65.90  ? 230 GLU A CB  1 
ATOM 7667 C CG  . GLU E 4 218 ? 155.706 189.363 177.193 1.00 65.90  ? 230 GLU A CG  1 
ATOM 7668 C CD  . GLU E 4 218 ? 155.366 188.866 178.583 1.00 65.90  ? 230 GLU A CD  1 
ATOM 7669 O OE1 . GLU E 4 218 ? 154.307 189.261 179.113 1.00 65.90  ? 230 GLU A OE1 1 
ATOM 7670 O OE2 . GLU E 4 218 ? 156.151 188.077 179.147 1.00 65.90  ? 230 GLU A OE2 1 
ATOM 7671 N N   . SER E 4 219 ? 158.038 193.329 176.057 1.00 59.60  ? 231 SER A N   1 
ATOM 7672 C CA  . SER E 4 219 ? 158.298 194.746 176.331 1.00 59.60  ? 231 SER A CA  1 
ATOM 7673 C C   . SER E 4 219 ? 159.273 195.401 175.359 1.00 59.60  ? 231 SER A C   1 
ATOM 7674 O O   . SER E 4 219 ? 159.279 196.634 175.294 1.00 59.60  ? 231 SER A O   1 
ATOM 7675 C CB  . SER E 4 219 ? 158.801 194.905 177.764 1.00 59.60  ? 231 SER A CB  1 
ATOM 7676 O OG  . SER E 4 219 ? 157.786 194.558 178.689 1.00 59.60  ? 231 SER A OG  1 
ATOM 7677 N N   . PHE E 4 220 ? 160.093 194.660 174.617 1.00 59.20  ? 232 PHE A N   1 
ATOM 7678 C CA  . PHE E 4 220 ? 160.978 195.308 173.654 1.00 59.20  ? 232 PHE A CA  1 
ATOM 7679 C C   . PHE E 4 220 ? 161.095 194.525 172.353 1.00 59.20  ? 232 PHE A C   1 
ATOM 7680 O O   . PHE E 4 220 ? 161.920 194.858 171.497 1.00 59.20  ? 232 PHE A O   1 
ATOM 7681 C CB  . PHE E 4 220 ? 162.364 195.521 174.256 1.00 59.20  ? 232 PHE A CB  1 
ATOM 7682 C CG  . PHE E 4 220 ? 163.196 196.512 173.504 1.00 59.20  ? 232 PHE A CG  1 
ATOM 7683 C CD1 . PHE E 4 220 ? 162.700 197.766 173.213 1.00 59.20  ? 232 PHE A CD1 1 
ATOM 7684 C CD2 . PHE E 4 220 ? 164.463 196.182 173.069 1.00 59.20  ? 232 PHE A CD2 1 
ATOM 7685 C CE1 . PHE E 4 220 ? 163.458 198.676 172.517 1.00 59.20  ? 232 PHE A CE1 1 
ATOM 7686 C CE2 . PHE E 4 220 ? 165.225 197.089 172.372 1.00 59.20  ? 232 PHE A CE2 1 
ATOM 7687 C CZ  . PHE E 4 220 ? 164.722 198.336 172.095 1.00 59.20  ? 232 PHE A CZ  1 
ATOM 7688 N N   . GLU E 4 221 ? 160.286 193.483 172.189 1.00 68.38  ? 233 GLU A N   1 
ATOM 7689 C CA  . GLU E 4 221 ? 160.268 192.767 170.921 1.00 68.38  ? 233 GLU A CA  1 
ATOM 7690 C C   . GLU E 4 221 ? 158.910 192.924 170.258 1.00 68.38  ? 233 GLU A C   1 
ATOM 7691 O O   . GLU E 4 221 ? 158.826 193.309 169.087 1.00 68.38  ? 233 GLU A O   1 
ATOM 7692 C CB  . GLU E 4 221 ? 160.601 191.289 171.116 1.00 68.38  ? 233 GLU A CB  1 
ATOM 7693 C CG  . GLU E 4 221 ? 160.481 190.472 169.842 1.00 68.38  ? 233 GLU A CG  1 
ATOM 7694 C CD  . GLU E 4 221 ? 161.490 189.344 169.772 1.00 68.38  ? 233 GLU A CD  1 
ATOM 7695 O OE1 . GLU E 4 221 ? 162.692 189.629 169.589 1.00 68.38  ? 233 GLU A OE1 1 
ATOM 7696 O OE2 . GLU E 4 221 ? 161.080 188.171 169.897 1.00 68.38  ? 233 GLU A OE2 1 
ATOM 7697 N N   . SER E 4 222 ? 157.842 192.631 170.997 1.00 63.47  ? 234 SER A N   1 
ATOM 7698 C CA  . SER E 4 222 ? 156.494 192.815 170.480 1.00 63.47  ? 234 SER A CA  1 
ATOM 7699 C C   . SER E 4 222 ? 156.257 194.280 170.147 1.00 63.47  ? 234 SER A C   1 
ATOM 7700 O O   . SER E 4 222 ? 155.767 194.603 169.061 1.00 63.47  ? 234 SER A O   1 
ATOM 7701 C CB  . SER E 4 222 ? 155.455 192.319 171.486 1.00 63.47  ? 234 SER A CB  1 
ATOM 7702 O OG  . SER E 4 222 ? 154.176 192.854 171.199 1.00 63.47  ? 234 SER A OG  1 
ATOM 7703 N N   . GLN E 4 223 ? 156.600 195.177 171.071 1.00 65.96  ? 235 GLN A N   1 
ATOM 7704 C CA  . GLN E 4 223 ? 156.487 196.599 170.784 1.00 65.96  ? 235 GLN A CA  1 
ATOM 7705 C C   . GLN E 4 223 ? 157.800 197.163 170.259 1.00 65.96  ? 235 GLN A C   1 
ATOM 7706 O O   . GLN E 4 223 ? 158.265 198.205 170.727 1.00 65.96  ? 235 GLN A O   1 
ATOM 7707 C CB  . GLN E 4 223 ? 156.055 197.363 172.036 1.00 65.96  ? 235 GLN A CB  1 
ATOM 7708 C CG  . GLN E 4 223 ? 155.130 198.530 171.758 1.00 65.96  ? 235 GLN A CG  1 
ATOM 7709 C CD  . GLN E 4 223 ? 154.358 198.960 172.986 1.00 65.96  ? 235 GLN A CD  1 
ATOM 7710 O OE1 . GLN E 4 223 ? 154.259 198.218 173.962 1.00 65.96  ? 235 GLN A OE1 1 
ATOM 7711 N NE2 . GLN E 4 223 ? 153.805 200.166 172.945 1.00 65.96  ? 235 GLN A NE2 1 
ATOM 7712 N N   . PHE E 4 224 ? 158.406 196.481 169.291 1.00 58.80  ? 236 PHE A N   1 
ATOM 7713 C CA  . PHE E 4 224 ? 159.485 197.063 168.505 1.00 58.80  ? 236 PHE A CA  1 
ATOM 7714 C C   . PHE E 4 224 ? 159.243 196.706 167.049 1.00 58.80  ? 236 PHE A C   1 
ATOM 7715 O O   . PHE E 4 224 ? 159.665 197.421 166.135 1.00 58.80  ? 236 PHE A O   1 
ATOM 7716 C CB  . PHE E 4 224 ? 160.851 196.563 168.979 1.00 58.80  ? 236 PHE A CB  1 
ATOM 7717 C CG  . PHE E 4 224 ? 161.967 196.809 167.999 1.00 58.80  ? 236 PHE A CG  1 
ATOM 7718 C CD1 . PHE E 4 224 ? 162.557 198.057 167.904 1.00 58.80  ? 236 PHE A CD1 1 
ATOM 7719 C CD2 . PHE E 4 224 ? 162.431 195.794 167.181 1.00 58.80  ? 236 PHE A CD2 1 
ATOM 7720 C CE1 . PHE E 4 224 ? 163.584 198.288 167.012 1.00 58.80  ? 236 PHE A CE1 1 
ATOM 7721 C CE2 . PHE E 4 224 ? 163.459 196.021 166.287 1.00 58.80  ? 236 PHE A CE2 1 
ATOM 7722 C CZ  . PHE E 4 224 ? 164.034 197.269 166.202 1.00 58.80  ? 236 PHE A CZ  1 
ATOM 7723 N N   . LEU E 4 225 ? 158.545 195.591 166.840 1.00 62.39  ? 237 LEU A N   1 
ATOM 7724 C CA  . LEU E 4 225 ? 158.296 195.105 165.489 1.00 62.39  ? 237 LEU A CA  1 
ATOM 7725 C C   . LEU E 4 225 ? 157.105 195.819 164.869 1.00 62.39  ? 237 LEU A C   1 
ATOM 7726 O O   . LEU E 4 225 ? 157.118 196.160 163.681 1.00 62.39  ? 237 LEU A O   1 
ATOM 7727 C CB  . LEU E 4 225 ? 158.068 193.599 165.528 1.00 62.39  ? 237 LEU A CB  1 
ATOM 7728 C CG  . LEU E 4 225 ? 159.324 192.777 165.804 1.00 62.39  ? 237 LEU A CG  1 
ATOM 7729 C CD1 . LEU E 4 225 ? 159.121 191.381 165.295 1.00 62.39  ? 237 LEU A CD1 1 
ATOM 7730 C CD2 . LEU E 4 225 ? 160.548 193.408 165.165 1.00 62.39  ? 237 LEU A CD2 1 
ATOM 7731 N N   . ALA E 4 226 ? 156.062 196.052 165.662 1.00 65.63  ? 238 ALA A N   1 
ATOM 7732 C CA  . ALA E 4 226 ? 154.911 196.812 165.197 1.00 65.63  ? 238 ALA A CA  1 
ATOM 7733 C C   . ALA E 4 226 ? 155.332 198.231 164.843 1.00 65.63  ? 238 ALA A C   1 
ATOM 7734 O O   . ALA E 4 226 ? 154.754 198.852 163.947 1.00 65.63  ? 238 ALA A O   1 
ATOM 7735 C CB  . ALA E 4 226 ? 153.807 196.825 166.256 1.00 65.63  ? 238 ALA A CB  1 
ATOM 7736 N N   . ASP E 4 227 ? 156.342 198.749 165.540 1.00 63.51  ? 239 ASP A N   1 
ATOM 7737 C CA  . ASP E 4 227 ? 156.817 200.101 165.282 1.00 63.51  ? 239 ASP A CA  1 
ATOM 7738 C C   . ASP E 4 227 ? 157.976 200.109 164.295 1.00 63.51  ? 239 ASP A C   1 
ATOM 7739 O O   . ASP E 4 227 ? 158.547 201.167 164.015 1.00 63.51  ? 239 ASP A O   1 
ATOM 7740 C CB  . ASP E 4 227 ? 157.232 200.785 166.584 1.00 63.51  ? 239 ASP A CB  1 
ATOM 7741 C CG  . ASP E 4 227 ? 157.145 202.295 166.496 1.00 63.51  ? 239 ASP A CG  1 
ATOM 7742 O OD1 . ASP E 4 227 ? 156.033 202.838 166.661 1.00 63.51  ? 239 ASP A OD1 1 
ATOM 7743 O OD2 . ASP E 4 227 ? 158.187 202.939 166.253 1.00 63.51  ? 239 ASP A OD2 1 
ATOM 7744 N N   . THR E 4 228 ? 158.346 198.942 163.768 1.00 66.02  ? 240 THR A N   1 
ATOM 7745 C CA  . THR E 4 228 ? 159.298 198.882 162.670 1.00 66.02  ? 240 THR A CA  1 
ATOM 7746 C C   . THR E 4 228 ? 158.628 198.539 161.348 1.00 66.02  ? 240 THR A C   1 
ATOM 7747 O O   . THR E 4 228 ? 159.252 198.704 160.293 1.00 66.02  ? 240 THR A O   1 
ATOM 7748 C CB  . THR E 4 228 ? 160.418 197.874 162.959 1.00 66.02  ? 240 THR A CB  1 
ATOM 7749 O OG1 . THR E 4 228 ? 161.584 198.235 162.209 1.00 66.02  ? 240 THR A OG1 1 
ATOM 7750 C CG2 . THR E 4 228 ? 160.001 196.474 162.550 1.00 66.02  ? 240 THR A CG2 1 
ATOM 7751 N N   . GLU E 4 229 ? 157.382 198.066 161.372 1.00 71.39  ? 241 GLU A N   1 
ATOM 7752 C CA  . GLU E 4 229 ? 156.603 197.951 160.145 1.00 71.39  ? 241 GLU A CA  1 
ATOM 7753 C C   . GLU E 4 229 ? 156.228 199.330 159.621 1.00 71.39  ? 241 GLU A C   1 
ATOM 7754 O O   . GLU E 4 229 ? 156.332 199.605 158.421 1.00 71.39  ? 241 GLU A O   1 
ATOM 7755 C CB  . GLU E 4 229 ? 155.338 197.124 160.393 1.00 71.39  ? 241 GLU A CB  1 
ATOM 7756 C CG  . GLU E 4 229 ? 155.564 195.711 160.896 1.00 71.39  ? 241 GLU A CG  1 
ATOM 7757 C CD  . GLU E 4 229 ? 155.939 194.744 159.795 1.00 71.39  ? 241 GLU A CD  1 
ATOM 7758 O OE1 . GLU E 4 229 ? 157.009 194.923 159.178 1.00 71.39  ? 241 GLU A OE1 1 
ATOM 7759 O OE2 . GLU E 4 229 ? 155.155 193.806 159.542 1.00 71.39  ? 241 GLU A OE2 1 
ATOM 7760 N N   . ARG E 4 230 ? 155.789 200.212 160.521 1.00 69.66  ? 242 ARG A N   1 
ATOM 7761 C CA  . ARG E 4 230 ? 155.275 201.515 160.120 1.00 69.66  ? 242 ARG A CA  1 
ATOM 7762 C C   . ARG E 4 230 ? 156.364 202.378 159.496 1.00 69.66  ? 242 ARG A C   1 
ATOM 7763 O O   . ARG E 4 230 ? 156.145 203.023 158.467 1.00 69.66  ? 242 ARG A O   1 
ATOM 7764 C CB  . ARG E 4 230 ? 154.645 202.217 161.323 1.00 69.66  ? 242 ARG A CB  1 
ATOM 7765 C CG  . ARG E 4 230 ? 153.144 202.018 161.429 1.00 69.66  ? 242 ARG A CG  1 
ATOM 7766 C CD  . ARG E 4 230 ? 152.578 202.720 162.651 1.00 69.66  ? 242 ARG A CD  1 
ATOM 7767 N NE  . ARG E 4 230 ? 153.046 202.121 163.895 1.00 69.66  ? 242 ARG A NE  1 
ATOM 7768 C CZ  . ARG E 4 230 ? 152.621 200.961 164.377 1.00 69.66  ? 242 ARG A CZ  1 
ATOM 7769 N NH1 . ARG E 4 230 ? 151.702 200.245 163.749 1.00 69.66  ? 242 ARG A NH1 1 
ATOM 7770 N NH2 . ARG E 4 230 ? 153.132 200.507 165.518 1.00 69.66  ? 242 ARG A NH2 1 
ATOM 7771 N N   . PHE E 4 231 ? 157.550 202.399 160.103 1.00 67.71  ? 243 PHE A N   1 
ATOM 7772 C CA  . PHE E 4 231 ? 158.631 203.234 159.592 1.00 67.71  ? 243 PHE A CA  1 
ATOM 7773 C C   . PHE E 4 231 ? 159.076 202.783 158.208 1.00 67.71  ? 243 PHE A C   1 
ATOM 7774 O O   . PHE E 4 231 ? 159.649 203.568 157.447 1.00 67.71  ? 243 PHE A O   1 
ATOM 7775 C CB  . PHE E 4 231 ? 159.826 203.229 160.542 1.00 67.71  ? 243 PHE A CB  1 
ATOM 7776 C CG  . PHE E 4 231 ? 161.001 204.008 160.030 1.00 67.71  ? 243 PHE A CG  1 
ATOM 7777 C CD1 . PHE E 4 231 ? 160.854 205.326 159.637 1.00 67.71  ? 243 PHE A CD1 1 
ATOM 7778 C CD2 . PHE E 4 231 ? 162.247 203.419 159.928 1.00 67.71  ? 243 PHE A CD2 1 
ATOM 7779 C CE1 . PHE E 4 231 ? 161.931 206.044 159.159 1.00 67.71  ? 243 PHE A CE1 1 
ATOM 7780 C CE2 . PHE E 4 231 ? 163.327 204.132 159.452 1.00 67.71  ? 243 PHE A CE2 1 
ATOM 7781 C CZ  . PHE E 4 231 ? 163.169 205.446 159.067 1.00 67.71  ? 243 PHE A CZ  1 
ATOM 7782 N N   . TYR E 4 232 ? 158.810 201.526 157.866 1.00 69.09  ? 244 TYR A N   1 
ATOM 7783 C CA  . TYR E 4 232 ? 159.169 200.998 156.558 1.00 69.09  ? 244 TYR A CA  1 
ATOM 7784 C C   . TYR E 4 232 ? 158.009 201.018 155.575 1.00 69.09  ? 244 TYR A C   1 
ATOM 7785 O O   . TYR E 4 232 ? 158.227 201.203 154.375 1.00 69.09  ? 244 TYR A O   1 
ATOM 7786 C CB  . TYR E 4 232 ? 159.734 199.580 156.702 1.00 69.09  ? 244 TYR A CB  1 
ATOM 7787 C CG  . TYR E 4 232 ? 161.231 199.584 156.893 1.00 69.09  ? 244 TYR A CG  1 
ATOM 7788 C CD1 . TYR E 4 232 ? 162.041 200.395 156.112 1.00 69.09  ? 244 TYR A CD1 1 
ATOM 7789 C CD2 . TYR E 4 232 ? 161.833 198.803 157.866 1.00 69.09  ? 244 TYR A CD2 1 
ATOM 7790 C CE1 . TYR E 4 232 ? 163.408 200.414 156.281 1.00 69.09  ? 244 TYR A CE1 1 
ATOM 7791 C CE2 . TYR E 4 232 ? 163.202 198.819 158.045 1.00 69.09  ? 244 TYR A CE2 1 
ATOM 7792 C CZ  . TYR E 4 232 ? 163.983 199.624 157.248 1.00 69.09  ? 244 TYR A CZ  1 
ATOM 7793 O OH  . TYR E 4 232 ? 165.346 199.641 157.422 1.00 69.09  ? 244 TYR A OH  1 
ATOM 7794 N N   . THR E 4 233 ? 156.773 200.847 156.044 1.00 67.94  ? 245 THR A N   1 
ATOM 7795 C CA  . THR E 4 233 ? 155.641 201.119 155.169 1.00 67.94  ? 245 THR A CA  1 
ATOM 7796 C C   . THR E 4 233 ? 155.218 202.569 155.393 1.00 67.94  ? 245 THR A C   1 
ATOM 7797 O O   . THR E 4 233 ? 154.037 202.879 155.575 1.00 67.94  ? 245 THR A O   1 
ATOM 7798 C CB  . THR E 4 233 ? 154.497 200.136 155.440 1.00 67.94  ? 245 THR A CB  1 
ATOM 7799 O OG1 . THR E 4 233 ? 155.007 198.800 155.388 1.00 67.94  ? 245 THR A OG1 1 
ATOM 7800 C CG2 . THR E 4 233 ? 153.418 200.248 154.367 1.00 67.94  ? 245 THR A CG2 1 
ATOM 7801 N N   . ARG E 4 234 ? 156.205 203.461 155.410 1.00 75.04  ? 246 ARG A N   1 
ATOM 7802 C CA  . ARG E 4 234 ? 155.997 204.901 155.342 1.00 75.04  ? 246 ARG A CA  1 
ATOM 7803 C C   . ARG E 4 234 ? 157.156 205.480 154.547 1.00 75.04  ? 246 ARG A C   1 
ATOM 7804 O O   . ARG E 4 234 ? 157.308 206.700 154.430 1.00 75.04  ? 246 ARG A O   1 
ATOM 7805 C CB  . ARG E 4 234 ? 155.900 205.517 156.736 1.00 75.04  ? 246 ARG A CB  1 
ATOM 7806 C CG  . ARG E 4 234 ? 155.039 206.763 156.811 1.00 75.04  ? 246 ARG A CG  1 
ATOM 7807 C CD  . ARG E 4 234 ? 155.880 207.987 157.128 1.00 75.04  ? 246 ARG A CD  1 
ATOM 7808 N NE  . ARG E 4 234 ? 156.590 207.837 158.393 1.00 75.04  ? 246 ARG A NE  1 
ATOM 7809 C CZ  . ARG E 4 234 ? 156.010 207.826 159.587 1.00 75.04  ? 246 ARG A CZ  1 
ATOM 7810 N NH1 . ARG E 4 234 ? 154.703 207.981 159.725 1.00 75.04  ? 246 ARG A NH1 1 
ATOM 7811 N NH2 . ARG E 4 234 ? 156.763 207.658 160.671 1.00 75.04  ? 246 ARG A NH2 1 
ATOM 7812 N N   . GLU E 4 235 ? 157.998 204.590 154.039 1.00 78.17  ? 247 GLU A N   1 
ATOM 7813 C CA  . GLU E 4 235 ? 159.079 204.901 153.117 1.00 78.17  ? 247 GLU A CA  1 
ATOM 7814 C C   . GLU E 4 235 ? 159.040 204.032 151.873 1.00 78.17  ? 247 GLU A C   1 
ATOM 7815 O O   . GLU E 4 235 ? 159.490 204.464 150.809 1.00 78.17  ? 247 GLU A O   1 
ATOM 7816 C CB  . GLU E 4 235 ? 160.437 204.735 153.813 1.00 78.17  ? 247 GLU A CB  1 
ATOM 7817 C CG  . GLU E 4 235 ? 161.521 205.659 153.291 1.00 78.17  ? 247 GLU A CG  1 
ATOM 7818 C CD  . GLU E 4 235 ? 162.901 205.271 153.781 1.00 78.17  ? 247 GLU A CD  1 
ATOM 7819 O OE1 . GLU E 4 235 ? 163.120 204.073 154.058 1.00 78.17  ? 247 GLU A OE1 1 
ATOM 7820 O OE2 . GLU E 4 235 ? 163.769 206.162 153.888 1.00 78.17  ? 247 GLU A OE2 1 
ATOM 7821 N N   . SER E 4 236 ? 158.511 202.813 151.983 1.00 81.95  ? 248 SER A N   1 
ATOM 7822 C CA  . SER E 4 236 ? 158.348 201.936 150.832 1.00 81.95  ? 248 SER A CA  1 
ATOM 7823 C C   . SER E 4 236 ? 157.362 202.540 149.842 1.00 81.95  ? 248 SER A C   1 
ATOM 7824 O O   . SER E 4 236 ? 157.735 202.859 148.708 1.00 81.95  ? 248 SER A O   1 
ATOM 7825 C CB  . SER E 4 236 ? 157.881 200.548 151.271 1.00 81.95  ? 248 SER A CB  1 
ATOM 7826 O OG  . SER E 4 236 ? 157.499 199.768 150.154 1.00 81.95  ? 248 SER A OG  1 
ATOM 7827 N N   . THR E 4 237 ? 156.106 202.715 150.254 1.00 81.73  ? 249 THR A N   1 
ATOM 7828 C CA  . THR E 4 237 ? 155.143 203.346 149.362 1.00 81.73  ? 249 THR A CA  1 
ATOM 7829 C C   . THR E 4 237 ? 155.200 204.859 149.520 1.00 81.73  ? 249 THR A C   1 
ATOM 7830 O O   . THR E 4 237 ? 154.164 205.521 149.628 1.00 81.73  ? 249 THR A O   1 
ATOM 7831 C CB  . THR E 4 237 ? 153.726 202.843 149.645 1.00 81.73  ? 249 THR A CB  1 
ATOM 7832 O OG1 . THR E 4 237 ? 153.256 203.404 150.876 1.00 81.73  ? 249 THR A OG1 1 
ATOM 7833 C CG2 . THR E 4 237 ? 153.708 201.330 149.753 1.00 81.73  ? 249 THR A CG2 1 
ATOM 7834 N N   . GLU E 4 238 ? 156.414 205.406 149.523 1.00 80.67  ? 250 GLU A N   1 
ATOM 7835 C CA  . GLU E 4 238 ? 156.656 206.837 149.401 1.00 80.67  ? 250 GLU A CA  1 
ATOM 7836 C C   . GLU E 4 238 ? 157.872 207.036 148.511 1.00 80.67  ? 250 GLU A C   1 
ATOM 7837 O O   . GLU E 4 238 ? 158.152 208.150 148.057 1.00 80.67  ? 250 GLU A O   1 
ATOM 7838 C CB  . GLU E 4 238 ? 156.861 207.493 150.770 1.00 80.67  ? 250 GLU A CB  1 
ATOM 7839 C CG  . GLU E 4 238 ? 155.767 207.225 151.808 1.00 80.67  ? 250 GLU A CG  1 
ATOM 7840 C CD  . GLU E 4 238 ? 154.450 207.943 151.529 1.00 80.67  ? 250 GLU A CD  1 
ATOM 7841 O OE1 . GLU E 4 238 ? 153.724 208.233 152.504 1.00 80.67  ? 250 GLU A OE1 1 
ATOM 7842 O OE2 . GLU E 4 238 ? 154.135 208.229 150.356 1.00 80.67  ? 250 GLU A OE2 1 
ATOM 7843 N N   . PHE E 4 239 ? 158.600 205.949 148.263 1.00 80.16  ? 251 PHE A N   1 
ATOM 7844 C CA  . PHE E 4 239 ? 159.745 205.943 147.363 1.00 80.16  ? 251 PHE A CA  1 
ATOM 7845 C C   . PHE E 4 239 ? 159.418 205.369 145.996 1.00 80.16  ? 251 PHE A C   1 
ATOM 7846 O O   . PHE E 4 239 ? 159.947 205.848 144.991 1.00 80.16  ? 251 PHE A O   1 
ATOM 7847 C CB  . PHE E 4 239 ? 160.904 205.154 147.980 1.00 80.16  ? 251 PHE A CB  1 
ATOM 7848 C CG  . PHE E 4 239 ? 162.255 205.661 147.581 1.00 80.16  ? 251 PHE A CG  1 
ATOM 7849 C CD1 . PHE E 4 239 ? 162.802 205.328 146.356 1.00 80.16  ? 251 PHE A CD1 1 
ATOM 7850 C CD2 . PHE E 4 239 ? 162.972 206.487 148.425 1.00 80.16  ? 251 PHE A CD2 1 
ATOM 7851 C CE1 . PHE E 4 239 ? 164.044 205.800 145.986 1.00 80.16  ? 251 PHE A CE1 1 
ATOM 7852 C CE2 . PHE E 4 239 ? 164.213 206.965 148.060 1.00 80.16  ? 251 PHE A CE2 1 
ATOM 7853 C CZ  . PHE E 4 239 ? 164.751 206.619 146.839 1.00 80.16  ? 251 PHE A CZ  1 
ATOM 7854 N N   . LEU E 4 240 ? 158.557 204.353 145.930 1.00 84.05  ? 252 LEU A N   1 
ATOM 7855 C CA  . LEU E 4 240 ? 157.996 203.915 144.655 1.00 84.05  ? 252 LEU A CA  1 
ATOM 7856 C C   . LEU E 4 240 ? 156.740 204.713 144.302 1.00 84.05  ? 252 LEU A C   1 
ATOM 7857 O O   . LEU E 4 240 ? 155.698 204.179 143.932 1.00 84.05  ? 252 LEU A O   1 
ATOM 7858 C CB  . LEU E 4 240 ? 157.753 202.402 144.728 1.00 84.05  ? 252 LEU A CB  1 
ATOM 7859 C CG  . LEU E 4 240 ? 157.082 201.364 143.803 1.00 84.05  ? 252 LEU A CG  1 
ATOM 7860 C CD1 . LEU E 4 240 ? 157.473 199.990 144.297 1.00 84.05  ? 252 LEU A CD1 1 
ATOM 7861 C CD2 . LEU E 4 240 ? 155.563 201.380 143.782 1.00 84.05  ? 252 LEU A CD2 1 
ATOM 7862 N N   . GLN E 4 241 ? 156.833 206.034 144.422 1.00 86.47  ? 253 GLN A N   1 
ATOM 7863 C CA  . GLN E 4 241 ? 155.789 206.928 143.948 1.00 86.47  ? 253 GLN A CA  1 
ATOM 7864 C C   . GLN E 4 241 ? 156.459 208.181 143.395 1.00 86.47  ? 253 GLN A C   1 
ATOM 7865 O O   . GLN E 4 241 ? 155.818 209.023 142.758 1.00 86.47  ? 253 GLN A O   1 
ATOM 7866 C CB  . GLN E 4 241 ? 154.803 207.220 145.089 1.00 86.47  ? 253 GLN A CB  1 
ATOM 7867 C CG  . GLN E 4 241 ? 153.912 208.441 144.941 1.00 86.47  ? 253 GLN A CG  1 
ATOM 7868 C CD  . GLN E 4 241 ? 154.552 209.695 145.500 1.00 86.47  ? 253 GLN A CD  1 
ATOM 7869 O OE1 . GLN E 4 241 ? 155.694 209.670 145.958 1.00 86.47  ? 253 GLN A OE1 1 
ATOM 7870 N NE2 . GLN E 4 241 ? 153.817 210.799 145.468 1.00 86.47  ? 253 GLN A NE2 1 
ATOM 7871 N N   . GLN E 4 242 ? 157.773 208.275 143.588 1.00 95.31  ? 254 GLN A N   1 
ATOM 7872 C CA  . GLN E 4 242 ? 158.521 209.471 143.222 1.00 95.31  ? 254 GLN A CA  1 
ATOM 7873 C C   . GLN E 4 242 ? 159.802 209.062 142.503 1.00 95.31  ? 254 GLN A C   1 
ATOM 7874 O O   . GLN E 4 242 ? 160.392 209.859 141.766 1.00 95.31  ? 254 GLN A O   1 
ATOM 7875 C CB  . GLN E 4 242 ? 158.735 210.328 144.490 1.00 95.31  ? 254 GLN A CB  1 
ATOM 7876 C CG  . GLN E 4 242 ? 159.717 211.533 144.497 1.00 95.31  ? 254 GLN A CG  1 
ATOM 7877 C CD  . GLN E 4 242 ? 161.171 211.223 144.179 1.00 95.31  ? 254 GLN A CD  1 
ATOM 7878 O OE1 . GLN E 4 242 ? 161.618 210.084 144.283 1.00 95.31  ? 254 GLN A OE1 1 
ATOM 7879 N NE2 . GLN E 4 242 ? 161.917 212.249 143.787 1.00 95.31  ? 254 GLN A NE2 1 
ATOM 7880 N N   . ASN E 4 243 ? 160.210 207.805 142.669 1.00 93.41  ? 255 ASN A N   1 
ATOM 7881 C CA  . ASN E 4 243 ? 161.412 207.274 142.038 1.00 93.41  ? 255 ASN A CA  1 
ATOM 7882 C C   . ASN E 4 243 ? 161.068 205.998 141.278 1.00 93.41  ? 255 ASN A C   1 
ATOM 7883 O O   . ASN E 4 243 ? 160.067 205.343 141.595 1.00 93.41  ? 255 ASN A O   1 
ATOM 7884 C CB  . ASN E 4 243 ? 162.497 206.990 143.081 1.00 93.41  ? 255 ASN A CB  1 
ATOM 7885 C CG  . ASN E 4 243 ? 163.554 208.077 143.143 1.00 93.41  ? 255 ASN A CG  1 
ATOM 7886 O OD1 . ASN E 4 243 ? 164.457 208.130 142.308 1.00 93.41  ? 255 ASN A OD1 1 
ATOM 7887 N ND2 . ASN E 4 243 ? 163.461 208.935 144.150 1.00 93.41  ? 255 ASN A ND2 1 
ATOM 7888 N N   . PRO E 4 244 ? 161.852 205.614 140.275 1.00 90.81  ? 256 PRO A N   1 
ATOM 7889 C CA  . PRO E 4 244 ? 161.603 204.345 139.588 1.00 90.81  ? 256 PRO A CA  1 
ATOM 7890 C C   . PRO E 4 244 ? 161.843 203.156 140.507 1.00 90.81  ? 256 PRO A C   1 
ATOM 7891 O O   . PRO E 4 244 ? 162.297 203.289 141.644 1.00 90.81  ? 256 PRO A O   1 
ATOM 7892 C CB  . PRO E 4 244 ? 162.611 204.365 138.433 1.00 90.81  ? 256 PRO A CB  1 
ATOM 7893 C CG  . PRO E 4 244 ? 163.704 205.252 138.920 1.00 90.81  ? 256 PRO A CG  1 
ATOM 7894 C CD  . PRO E 4 244 ? 162.994 206.333 139.684 1.00 90.81  ? 256 PRO A CD  1 
ATOM 7895 N N   . VAL E 4 245 ? 161.539 201.971 139.981 1.00 84.57  ? 257 VAL A N   1 
ATOM 7896 C CA  . VAL E 4 245 ? 161.617 200.746 140.768 1.00 84.57  ? 257 VAL A CA  1 
ATOM 7897 C C   . VAL E 4 245 ? 163.084 200.374 140.929 1.00 84.57  ? 257 VAL A C   1 
ATOM 7898 O O   . VAL E 4 245 ? 163.442 199.548 141.775 1.00 84.57  ? 257 VAL A O   1 
ATOM 7899 C CB  . VAL E 4 245 ? 160.812 199.613 140.103 1.00 84.57  ? 257 VAL A CB  1 
ATOM 7900 C CG1 . VAL E 4 245 ? 160.781 198.368 140.979 1.00 84.57  ? 257 VAL A CG1 1 
ATOM 7901 C CG2 . VAL E 4 245 ? 159.405 200.081 139.792 1.00 84.57  ? 257 VAL A CG2 1 
ATOM 7902 N N   . THR E 4 246 ? 163.950 201.039 140.170 1.00 92.95  ? 258 THR A N   1 
ATOM 7903 C CA  . THR E 4 246 ? 165.359 200.672 140.126 1.00 92.95  ? 258 THR A CA  1 
ATOM 7904 C C   . THR E 4 246 ? 166.088 201.200 141.358 1.00 92.95  ? 258 THR A C   1 
ATOM 7905 O O   . THR E 4 246 ? 167.251 200.861 141.597 1.00 92.95  ? 258 THR A O   1 
ATOM 7906 C CB  . THR E 4 246 ? 165.992 201.209 138.840 1.00 92.95  ? 258 THR A CB  1 
ATOM 7907 O OG1 . THR E 4 246 ? 165.141 200.899 137.730 1.00 92.95  ? 258 THR A OG1 1 
ATOM 7908 C CG2 . THR E 4 246 ? 167.348 200.575 138.594 1.00 92.95  ? 258 THR A CG2 1 
ATOM 7909 N N   . GLU E 4 247 ? 165.400 201.996 142.174 1.00 93.97  ? 259 GLU A N   1 
ATOM 7910 C CA  . GLU E 4 247 ? 166.008 202.521 143.389 1.00 93.97  ? 259 GLU A CA  1 
ATOM 7911 C C   . GLU E 4 247 ? 165.442 201.806 144.607 1.00 93.97  ? 259 GLU A C   1 
ATOM 7912 O O   . GLU E 4 247 ? 166.115 201.692 145.637 1.00 93.97  ? 259 GLU A O   1 
ATOM 7913 C CB  . GLU E 4 247 ? 165.792 204.033 143.493 1.00 93.97  ? 259 GLU A CB  1 
ATOM 7914 C CG  . GLU E 4 247 ? 166.355 204.875 142.334 1.00 93.97  ? 259 GLU A CG  1 
ATOM 7915 C CD  . GLU E 4 247 ? 167.679 204.375 141.754 1.00 93.97  ? 259 GLU A CD  1 
ATOM 7916 O OE1 . GLU E 4 247 ? 168.504 203.792 142.491 1.00 93.97  ? 259 GLU A OE1 1 
ATOM 7917 O OE2 . GLU E 4 247 ? 167.893 204.568 140.539 1.00 93.97  ? 259 GLU A OE2 1 
ATOM 7918 N N   . TYR E 4 248 ? 164.213 201.317 144.498 1.00 84.81  ? 260 TYR A N   1 
ATOM 7919 C CA  . TYR E 4 248 ? 163.705 200.436 145.537 1.00 84.81  ? 260 TYR A CA  1 
ATOM 7920 C C   . TYR E 4 248 ? 164.446 199.101 145.520 1.00 84.81  ? 260 TYR A C   1 
ATOM 7921 O O   . TYR E 4 248 ? 164.624 198.430 146.538 1.00 84.81  ? 260 TYR A O   1 
ATOM 7922 C CB  . TYR E 4 248 ? 162.199 200.237 145.340 1.00 84.81  ? 260 TYR A CB  1 
ATOM 7923 C CG  . TYR E 4 248 ? 161.435 199.606 146.492 1.00 84.81  ? 260 TYR A CG  1 
ATOM 7924 C CD1 . TYR E 4 248 ? 162.082 199.104 147.610 1.00 84.81  ? 260 TYR A CD1 1 
ATOM 7925 C CD2 . TYR E 4 248 ? 160.051 199.582 146.483 1.00 84.81  ? 260 TYR A CD2 1 
ATOM 7926 C CE1 . TYR E 4 248 ? 161.377 198.549 148.657 1.00 84.81  ? 260 TYR A CE1 1 
ATOM 7927 C CE2 . TYR E 4 248 ? 159.335 199.028 147.523 1.00 84.81  ? 260 TYR A CE2 1 
ATOM 7928 C CZ  . TYR E 4 248 ? 160.003 198.516 148.610 1.00 84.81  ? 260 TYR A CZ  1 
ATOM 7929 O OH  . TYR E 4 248 ? 159.292 197.968 149.653 1.00 84.81  ? 260 TYR A OH  1 
ATOM 7930 N N   . MET E 4 249 ? 164.951 198.720 144.346 1.00 91.23  ? 261 MET A N   1 
ATOM 7931 C CA  . MET E 4 249 ? 165.769 197.524 144.203 1.00 91.23  ? 261 MET A CA  1 
ATOM 7932 C C   . MET E 4 249 ? 167.151 197.702 144.814 1.00 91.23  ? 261 MET A C   1 
ATOM 7933 O O   . MET E 4 249 ? 167.878 196.716 144.982 1.00 91.23  ? 261 MET A O   1 
ATOM 7934 C CB  . MET E 4 249 ? 165.915 197.149 142.725 1.00 91.23  ? 261 MET A CB  1 
ATOM 7935 C CG  . MET E 4 249 ? 165.217 195.871 142.322 1.00 91.23  ? 261 MET A CG  1 
ATOM 7936 S SD  . MET E 4 249 ? 165.125 195.687 140.530 1.00 91.23  ? 261 MET A SD  1 
ATOM 7937 C CE  . MET E 4 249 ? 164.136 197.099 140.059 1.00 91.23  ? 261 MET A CE  1 
ATOM 7938 N N   . LYS E 4 250 ? 167.527 198.932 145.164 1.00 87.64  ? 262 LYS A N   1 
ATOM 7939 C CA  . LYS E 4 250 ? 168.834 199.198 145.744 1.00 87.64  ? 262 LYS A CA  1 
ATOM 7940 C C   . LYS E 4 250 ? 168.750 199.763 147.153 1.00 87.64  ? 262 LYS A C   1 
ATOM 7941 O O   . LYS E 4 250 ? 169.732 199.666 147.895 1.00 87.64  ? 262 LYS A O   1 
ATOM 7942 C CB  . LYS E 4 250 ? 169.625 200.163 144.847 1.00 87.64  ? 262 LYS A CB  1 
ATOM 7943 C CG  . LYS E 4 250 ? 171.130 200.106 145.028 1.00 87.64  ? 262 LYS A CG  1 
ATOM 7944 C CD  . LYS E 4 250 ? 171.768 201.440 144.690 1.00 87.64  ? 262 LYS A CD  1 
ATOM 7945 C CE  . LYS E 4 250 ? 171.460 201.838 143.255 1.00 87.64  ? 262 LYS A CE  1 
ATOM 7946 N NZ  . LYS E 4 250 ? 172.288 201.095 142.266 1.00 87.64  ? 262 LYS A NZ  1 
ATOM 7947 N N   . LYS E 4 251 ? 167.621 200.350 147.544 1.00 80.69  ? 263 LYS A N   1 
ATOM 7948 C CA  . LYS E 4 251 ? 167.396 200.734 148.930 1.00 80.69  ? 263 LYS A CA  1 
ATOM 7949 C C   . LYS E 4 251 ? 167.103 199.498 149.767 1.00 80.69  ? 263 LYS A C   1 
ATOM 7950 O O   . LYS E 4 251 ? 167.544 199.399 150.917 1.00 80.69  ? 263 LYS A O   1 
ATOM 7951 C CB  . LYS E 4 251 ? 166.247 201.735 149.036 1.00 80.69  ? 263 LYS A CB  1 
ATOM 7952 C CG  . LYS E 4 251 ? 165.852 202.067 150.465 1.00 80.69  ? 263 LYS A CG  1 
ATOM 7953 C CD  . LYS E 4 251 ? 165.035 203.343 150.536 1.00 80.69  ? 263 LYS A CD  1 
ATOM 7954 C CE  . LYS E 4 251 ? 165.806 204.531 149.985 1.00 80.69  ? 263 LYS A CE  1 
ATOM 7955 N NZ  . LYS E 4 251 ? 167.255 204.489 150.331 1.00 80.69  ? 263 LYS A NZ  1 
ATOM 7956 N N   . ALA E 4 252 ? 166.349 198.559 149.195 1.00 81.29  ? 264 ALA A N   1 
ATOM 7957 C CA  . ALA E 4 252 ? 165.981 197.328 149.882 1.00 81.29  ? 264 ALA A CA  1 
ATOM 7958 C C   . ALA E 4 252 ? 167.211 196.592 150.390 1.00 81.29  ? 264 ALA A C   1 
ATOM 7959 O O   . ALA E 4 252 ? 167.252 196.177 151.552 1.00 81.29  ? 264 ALA A O   1 
ATOM 7960 C CB  . ALA E 4 252 ? 165.170 196.419 148.960 1.00 81.29  ? 264 ALA A CB  1 
ATOM 7961 N N   . GLU E 4 253 ? 168.218 196.430 149.533 1.00 81.73  ? 265 GLU A N   1 
ATOM 7962 C CA  . GLU E 4 253 ? 169.446 195.749 149.925 1.00 81.73  ? 265 GLU A CA  1 
ATOM 7963 C C   . GLU E 4 253 ? 170.107 196.448 151.104 1.00 81.73  ? 265 GLU A C   1 
ATOM 7964 O O   . GLU E 4 253 ? 170.569 195.789 152.039 1.00 81.73  ? 265 GLU A O   1 
ATOM 7965 C CB  . GLU E 4 253 ? 170.418 195.664 148.748 1.00 81.73  ? 265 GLU A CB  1 
ATOM 7966 C CG  . GLU E 4 253 ? 170.076 194.584 147.736 1.00 81.73  ? 265 GLU A CG  1 
ATOM 7967 C CD  . GLU E 4 253 ? 170.651 193.231 148.111 1.00 81.73  ? 265 GLU A CD  1 
ATOM 7968 O OE1 . GLU E 4 253 ? 170.430 192.780 149.255 1.00 81.73  ? 265 GLU A OE1 1 
ATOM 7969 O OE2 . GLU E 4 253 ? 171.327 192.616 147.260 1.00 81.73  ? 265 GLU A OE2 1 
ATOM 7970 N N   . ALA E 4 254 ? 170.161 197.778 151.068 1.00 74.50  ? 266 ALA A N   1 
ATOM 7971 C CA  . ALA E 4 254 ? 170.757 198.535 152.160 1.00 74.50  ? 266 ALA A CA  1 
ATOM 7972 C C   . ALA E 4 254 ? 169.972 198.353 153.454 1.00 74.50  ? 266 ALA A C   1 
ATOM 7973 O O   . ALA E 4 254 ? 170.546 197.998 154.487 1.00 74.50  ? 266 ALA A O   1 
ATOM 7974 C CB  . ALA E 4 254 ? 170.843 200.019 151.799 1.00 74.50  ? 266 ALA A CB  1 
ATOM 7975 N N   . ARG E 4 255 ? 168.658 198.582 153.403 1.00 71.77  ? 267 ARG A N   1 
ATOM 7976 C CA  . ARG E 4 255 ? 167.844 198.512 154.613 1.00 71.77  ? 267 ARG A CA  1 
ATOM 7977 C C   . ARG E 4 255 ? 167.762 197.090 155.153 1.00 71.77  ? 267 ARG A C   1 
ATOM 7978 O O   . ARG E 4 255 ? 167.799 196.873 156.369 1.00 71.77  ? 267 ARG A O   1 
ATOM 7979 C CB  . ARG E 4 255 ? 166.448 199.070 154.337 1.00 71.77  ? 267 ARG A CB  1 
ATOM 7980 C CG  . ARG E 4 255 ? 166.415 200.577 154.169 1.00 71.77  ? 267 ARG A CG  1 
ATOM 7981 C CD  . ARG E 4 255 ? 167.185 201.268 155.289 1.00 71.77  ? 267 ARG A CD  1 
ATOM 7982 N NE  . ARG E 4 255 ? 167.234 202.719 155.144 1.00 71.77  ? 267 ARG A NE  1 
ATOM 7983 C CZ  . ARG E 4 255 ? 166.179 203.524 155.172 1.00 71.77  ? 267 ARG A CZ  1 
ATOM 7984 N NH1 . ARG E 4 255 ? 164.957 203.061 155.373 1.00 71.77  ? 267 ARG A NH1 1 
ATOM 7985 N NH2 . ARG E 4 255 ? 166.358 204.831 155.004 1.00 71.77  ? 267 ARG A NH2 1 
ATOM 7986 N N   . LEU E 4 256 ? 167.648 196.105 154.263 1.00 67.69  ? 268 LEU A N   1 
ATOM 7987 C CA  . LEU E 4 256 ? 167.570 194.714 154.691 1.00 67.69  ? 268 LEU A CA  1 
ATOM 7988 C C   . LEU E 4 256 ? 168.899 194.278 155.292 1.00 67.69  ? 268 LEU A C   1 
ATOM 7989 O O   . LEU E 4 256 ? 168.947 193.354 156.110 1.00 67.69  ? 268 LEU A O   1 
ATOM 7990 C CB  . LEU E 4 256 ? 167.183 193.811 153.520 1.00 67.69  ? 268 LEU A CB  1 
ATOM 7991 C CG  . LEU E 4 256 ? 166.951 192.329 153.807 1.00 67.69  ? 268 LEU A CG  1 
ATOM 7992 C CD1 . LEU E 4 256 ? 166.138 192.149 155.077 1.00 67.69  ? 268 LEU A CD1 1 
ATOM 7993 C CD2 . LEU E 4 256 ? 166.257 191.676 152.628 1.00 67.69  ? 268 LEU A CD2 1 
ATOM 7994 N N   . LEU E 4 257 ? 169.984 194.942 154.895 1.00 65.89  ? 269 LEU A N   1 
ATOM 7995 C CA  . LEU E 4 257 ? 171.300 194.706 155.476 1.00 65.89  ? 269 LEU A CA  1 
ATOM 7996 C C   . LEU E 4 257 ? 171.508 195.609 156.686 1.00 65.89  ? 269 LEU A C   1 
ATOM 7997 O O   . LEU E 4 257 ? 172.157 195.204 157.653 1.00 65.89  ? 269 LEU A O   1 
ATOM 7998 C CB  . LEU E 4 257 ? 172.401 194.917 154.435 1.00 65.89  ? 269 LEU A CB  1 
ATOM 7999 C CG  . LEU E 4 257 ? 173.799 194.441 154.826 1.00 65.89  ? 269 LEU A CG  1 
ATOM 8000 C CD1 . LEU E 4 257 ? 173.733 193.089 155.515 1.00 65.89  ? 269 LEU A CD1 1 
ATOM 8001 C CD2 . LEU E 4 257 ? 174.699 194.378 153.604 1.00 65.89  ? 269 LEU A CD2 1 
ATOM 8002 N N   . GLU E 4 258 ? 170.977 196.833 156.657 1.00 66.50  ? 270 GLU A N   1 
ATOM 8003 C CA  . GLU E 4 258 ? 171.076 197.717 157.811 1.00 66.50  ? 270 GLU A CA  1 
ATOM 8004 C C   . GLU E 4 258 ? 170.293 197.152 158.991 1.00 66.50  ? 270 GLU A C   1 
ATOM 8005 O O   . GLU E 4 258 ? 170.721 197.262 160.144 1.00 66.50  ? 270 GLU A O   1 
ATOM 8006 C CB  . GLU E 4 258 ? 170.587 199.121 157.444 1.00 66.50  ? 270 GLU A CB  1 
ATOM 8007 C CG  . GLU E 4 258 ? 171.185 200.223 158.303 1.00 66.50  ? 270 GLU A CG  1 
ATOM 8008 C CD  . GLU E 4 258 ? 170.383 201.506 158.251 1.00 66.50  ? 270 GLU A CD  1 
ATOM 8009 O OE1 . GLU E 4 258 ? 170.228 202.069 157.147 1.00 66.50  ? 270 GLU A OE1 1 
ATOM 8010 O OE2 . GLU E 4 258 ? 169.908 201.956 159.314 1.00 66.50  ? 270 GLU A OE2 1 
ATOM 8011 N N   . GLU E 4 259 ? 169.141 196.535 158.720 1.00 66.76  ? 271 GLU A N   1 
ATOM 8012 C CA  . GLU E 4 259 ? 168.434 195.830 159.781 1.00 66.76  ? 271 GLU A CA  1 
ATOM 8013 C C   . GLU E 4 259 ? 168.977 194.414 159.914 1.00 66.76  ? 271 GLU A C   1 
ATOM 8014 O O   . GLU E 4 259 ? 168.218 193.450 160.045 1.00 66.76  ? 271 GLU A O   1 
ATOM 8015 C CB  . GLU E 4 259 ? 166.932 195.798 159.498 1.00 66.76  ? 271 GLU A CB  1 
ATOM 8016 C CG  . GLU E 4 259 ? 166.259 197.149 159.592 1.00 66.76  ? 271 GLU A CG  1 
ATOM 8017 C CD  . GLU E 4 259 ? 166.886 198.029 160.647 1.00 66.76  ? 271 GLU A CD  1 
ATOM 8018 O OE1 . GLU E 4 259 ? 167.727 198.884 160.298 1.00 66.76  ? 271 GLU A OE1 1 
ATOM 8019 O OE2 . GLU E 4 259 ? 166.532 197.864 161.831 1.00 66.76  ? 271 GLU A OE2 1 
ATOM 8020 N N   . GLN E 4 260 ? 170.302 194.295 159.891 1.00 64.99  ? 272 GLN A N   1 
ATOM 8021 C CA  . GLN E 4 260 ? 171.033 193.114 160.323 1.00 64.99  ? 272 GLN A CA  1 
ATOM 8022 C C   . GLN E 4 260 ? 172.311 193.568 161.019 1.00 64.99  ? 272 GLN A C   1 
ATOM 8023 O O   . GLN E 4 260 ? 173.080 192.753 161.540 1.00 64.99  ? 272 GLN A O   1 
ATOM 8024 C CB  . GLN E 4 260 ? 171.308 192.188 159.129 1.00 64.99  ? 272 GLN A CB  1 
ATOM 8025 C CG  . GLN E 4 260 ? 172.201 190.984 159.387 1.00 64.99  ? 272 GLN A CG  1 
ATOM 8026 C CD  . GLN E 4 260 ? 171.921 189.843 158.430 1.00 64.99  ? 272 GLN A CD  1 
ATOM 8027 O OE1 . GLN E 4 260 ? 172.638 189.649 157.448 1.00 64.99  ? 272 GLN A OE1 1 
ATOM 8028 N NE2 . GLN E 4 260 ? 170.875 189.076 158.715 1.00 64.99  ? 272 GLN A NE2 1 
ATOM 8029 N N   . ARG E 4 261 ? 172.508 194.888 161.075 1.00 61.45  ? 273 ARG A N   1 
ATOM 8030 C CA  . ARG E 4 261 ? 173.588 195.508 161.828 1.00 61.45  ? 273 ARG A CA  1 
ATOM 8031 C C   . ARG E 4 261 ? 173.029 196.410 162.922 1.00 61.45  ? 273 ARG A C   1 
ATOM 8032 O O   . ARG E 4 261 ? 173.797 196.938 163.735 1.00 61.45  ? 273 ARG A O   1 
ATOM 8033 C CB  . ARG E 4 261 ? 174.513 196.302 160.902 1.00 61.45  ? 273 ARG A CB  1 
ATOM 8034 C CG  . ARG E 4 261 ? 175.977 196.264 161.301 1.00 61.45  ? 273 ARG A CG  1 
ATOM 8035 C CD  . ARG E 4 261 ? 176.714 197.493 160.790 1.00 61.45  ? 273 ARG A CD  1 
ATOM 8036 N NE  . ARG E 4 261 ? 176.034 198.733 161.150 1.00 61.45  ? 273 ARG A NE  1 
ATOM 8037 C CZ  . ARG E 4 261 ? 175.925 199.206 162.384 1.00 61.45  ? 273 ARG A CZ  1 
ATOM 8038 N NH1 . ARG E 4 261 ? 176.470 198.584 163.416 1.00 61.45  ? 273 ARG A NH1 1 
ATOM 8039 N NH2 . ARG E 4 261 ? 175.255 200.337 162.587 1.00 61.45  ? 273 ARG A NH2 1 
ATOM 8040 N N   . ARG E 4 262 ? 171.708 196.599 162.956 1.00 59.15  ? 274 ARG A N   1 
ATOM 8041 C CA  . ARG E 4 262 ? 171.017 197.198 164.090 1.00 59.15  ? 274 ARG A CA  1 
ATOM 8042 C C   . ARG E 4 262 ? 170.698 196.108 165.107 1.00 59.15  ? 274 ARG A C   1 
ATOM 8043 O O   . ARG E 4 262 ? 170.042 196.339 166.121 1.00 59.15  ? 274 ARG A O   1 
ATOM 8044 C CB  . ARG E 4 262 ? 169.759 197.938 163.632 1.00 59.15  ? 274 ARG A CB  1 
ATOM 8045 C CG  . ARG E 4 262 ? 169.042 198.734 164.714 1.00 59.15  ? 274 ARG A CG  1 
ATOM 8046 C CD  . ARG E 4 262 ? 167.795 199.424 164.179 1.00 59.15  ? 274 ARG A CD  1 
ATOM 8047 N NE  . ARG E 4 262 ? 167.974 200.025 162.860 1.00 59.15  ? 274 ARG A NE  1 
ATOM 8048 C CZ  . ARG E 4 262 ? 168.852 200.974 162.560 1.00 59.15  ? 274 ARG A CZ  1 
ATOM 8049 N NH1 . ARG E 4 262 ? 169.651 201.497 163.476 1.00 59.15  ? 274 ARG A NH1 1 
ATOM 8050 N NH2 . ARG E 4 262 ? 168.923 201.419 161.310 1.00 59.15  ? 274 ARG A NH2 1 
ATOM 8051 N N   . VAL E 4 263 ? 171.137 194.891 164.807 1.00 57.37  ? 275 VAL A N   1 
ATOM 8052 C CA  . VAL E 4 263 ? 171.364 193.868 165.815 1.00 57.37  ? 275 VAL A CA  1 
ATOM 8053 C C   . VAL E 4 263 ? 172.870 193.903 166.041 1.00 57.37  ? 275 VAL A C   1 
ATOM 8054 O O   . VAL E 4 263 ? 173.594 194.543 165.271 1.00 57.37  ? 275 VAL A O   1 
ATOM 8055 C CB  . VAL E 4 263 ? 170.854 192.490 165.352 1.00 57.37  ? 275 VAL A CB  1 
ATOM 8056 C CG1 . VAL E 4 263 ? 170.930 191.466 166.472 1.00 57.37  ? 275 VAL A CG1 1 
ATOM 8057 C CG2 . VAL E 4 263 ? 169.430 192.609 164.842 1.00 57.37  ? 275 VAL A CG2 1 
ATOM 8058 N N   . GLN E 4 264 ? 173.352 193.256 167.100 1.00 61.54  ? 276 GLN A N   1 
ATOM 8059 C CA  . GLN E 4 264 ? 174.768 193.276 167.473 1.00 61.54  ? 276 GLN A CA  1 
ATOM 8060 C C   . GLN E 4 264 ? 175.206 194.689 167.864 1.00 61.54  ? 276 GLN A C   1 
ATOM 8061 O O   . GLN E 4 264 ? 176.208 195.210 167.377 1.00 61.54  ? 276 GLN A O   1 
ATOM 8062 C CB  . GLN E 4 264 ? 175.649 192.715 166.351 1.00 61.54  ? 276 GLN A CB  1 
ATOM 8063 C CG  . GLN E 4 264 ? 175.145 191.418 165.743 1.00 61.54  ? 276 GLN A CG  1 
ATOM 8064 C CD  . GLN E 4 264 ? 175.977 190.973 164.556 1.00 61.54  ? 276 GLN A CD  1 
ATOM 8065 O OE1 . GLN E 4 264 ? 176.999 191.580 164.239 1.00 61.54  ? 276 GLN A OE1 1 
ATOM 8066 N NE2 . GLN E 4 264 ? 175.541 189.910 163.892 1.00 61.54  ? 276 GLN A NE2 1 
ATOM 8067 N N   . VAL E 4 265 ? 174.416 195.275 168.778 1.00 58.57  ? 277 VAL A N   1 
ATOM 8068 C CA  . VAL E 4 265 ? 174.514 196.570 169.471 1.00 58.57  ? 277 VAL A CA  1 
ATOM 8069 C C   . VAL E 4 265 ? 173.106 196.903 169.946 1.00 58.57  ? 277 VAL A C   1 
ATOM 8070 O O   . VAL E 4 265 ? 172.875 197.928 170.595 1.00 58.57  ? 277 VAL A O   1 
ATOM 8071 C CB  . VAL E 4 265 ? 175.081 197.749 168.643 1.00 58.57  ? 277 VAL A CB  1 
ATOM 8072 C CG1 . VAL E 4 265 ? 176.612 197.743 168.587 1.00 58.57  ? 277 VAL A CG1 1 
ATOM 8073 C CG2 . VAL E 4 265 ? 174.466 197.803 167.245 1.00 58.57  ? 277 VAL A CG2 1 
ATOM 8074 N N   . TYR E 4 266 ? 172.165 196.020 169.622 1.00 62.02  ? 278 TYR A N   1 
ATOM 8075 C CA  . TYR E 4 266 ? 170.803 195.985 170.139 1.00 62.02  ? 278 TYR A CA  1 
ATOM 8076 C C   . TYR E 4 266 ? 170.417 194.515 170.082 1.00 62.02  ? 278 TYR A C   1 
ATOM 8077 O O   . TYR E 4 266 ? 170.073 194.003 169.013 1.00 62.02  ? 278 TYR A O   1 
ATOM 8078 C CB  . TYR E 4 266 ? 169.851 196.859 169.316 1.00 62.02  ? 278 TYR A CB  1 
ATOM 8079 C CG  . TYR E 4 266 ? 170.378 198.240 168.973 1.00 62.02  ? 278 TYR A CG  1 
ATOM 8080 C CD1 . TYR E 4 266 ? 170.206 199.303 169.841 1.00 62.02  ? 278 TYR A CD1 1 
ATOM 8081 C CD2 . TYR E 4 266 ? 171.049 198.479 167.784 1.00 62.02  ? 278 TYR A CD2 1 
ATOM 8082 C CE1 . TYR E 4 266 ? 170.682 200.563 169.533 1.00 62.02  ? 278 TYR A CE1 1 
ATOM 8083 C CE2 . TYR E 4 266 ? 171.527 199.732 167.467 1.00 62.02  ? 278 TYR A CE2 1 
ATOM 8084 C CZ  . TYR E 4 266 ? 171.343 200.770 168.344 1.00 62.02  ? 278 TYR A CZ  1 
ATOM 8085 O OH  . TYR E 4 266 ? 171.822 202.020 168.030 1.00 62.02  ? 278 TYR A OH  1 
ATOM 8086 N N   . LEU E 4 267 ? 170.454 193.827 171.220 1.00 69.70  ? 279 LEU A N   1 
ATOM 8087 C CA  . LEU E 4 267 ? 171.019 192.483 171.207 1.00 69.70  ? 279 LEU A CA  1 
ATOM 8088 C C   . LEU E 4 267 ? 170.339 191.475 172.119 1.00 69.70  ? 279 LEU A C   1 
ATOM 8089 O O   . LEU E 4 267 ? 169.158 191.611 172.453 1.00 69.70  ? 279 LEU A O   1 
ATOM 8090 C CB  . LEU E 4 267 ? 172.502 192.549 171.580 1.00 69.70  ? 279 LEU A CB  1 
ATOM 8091 C CG  . LEU E 4 267 ? 173.507 192.069 170.532 1.00 69.70  ? 279 LEU A CG  1 
ATOM 8092 C CD1 . LEU E 4 267 ? 174.915 192.040 171.111 1.00 69.70  ? 279 LEU A CD1 1 
ATOM 8093 C CD2 . LEU E 4 267 ? 173.125 190.709 169.961 1.00 69.70  ? 279 LEU A CD2 1 
ATOM 8094 N N   . HIS E 4 268 ? 171.110 190.437 172.466 1.00 73.62  ? 280 HIS A N   1 
ATOM 8095 C CA  . HIS E 4 268 ? 170.723 189.175 173.089 1.00 73.62  ? 280 HIS A CA  1 
ATOM 8096 C C   . HIS E 4 268 ? 170.225 188.236 171.995 1.00 73.62  ? 280 HIS A C   1 
ATOM 8097 O O   . HIS E 4 268 ? 169.870 187.082 172.261 1.00 73.62  ? 280 HIS A O   1 
ATOM 8098 C CB  . HIS E 4 268 ? 169.681 189.374 174.197 1.00 73.62  ? 280 HIS A CB  1 
ATOM 8099 C CG  . HIS E 4 268 ? 168.938 188.128 174.558 1.00 73.62  ? 280 HIS A CG  1 
ATOM 8100 N ND1 . HIS E 4 268 ? 169.568 186.913 174.713 1.00 73.62  ? 280 HIS A ND1 1 
ATOM 8101 C CD2 . HIS E 4 268 ? 167.620 187.898 174.760 1.00 73.62  ? 280 HIS A CD2 1 
ATOM 8102 C CE1 . HIS E 4 268 ? 168.673 185.990 175.014 1.00 73.62  ? 280 HIS A CE1 1 
ATOM 8103 N NE2 . HIS E 4 268 ? 167.483 186.562 175.049 1.00 73.62  ? 280 HIS A NE2 1 
ATOM 8104 N N   . GLU E 4 269 ? 170.259 188.709 170.748 1.00 75.07  ? 281 GLU A N   1 
ATOM 8105 C CA  . GLU E 4 269 ? 169.908 187.888 169.596 1.00 75.07  ? 281 GLU A CA  1 
ATOM 8106 C C   . GLU E 4 269 ? 168.496 187.344 169.742 1.00 75.07  ? 281 GLU A C   1 
ATOM 8107 O O   . GLU E 4 269 ? 167.640 187.992 170.352 1.00 75.07  ? 281 GLU A O   1 
ATOM 8108 C CB  . GLU E 4 269 ? 170.910 186.746 169.418 1.00 75.07  ? 281 GLU A CB  1 
ATOM 8109 C CG  . GLU E 4 269 ? 172.183 187.149 168.702 1.00 75.07  ? 281 GLU A CG  1 
ATOM 8110 C CD  . GLU E 4 269 ? 173.358 186.270 169.077 1.00 75.07  ? 281 GLU A CD  1 
ATOM 8111 O OE1 . GLU E 4 269 ? 174.437 186.818 169.388 1.00 75.07  ? 281 GLU A OE1 1 
ATOM 8112 O OE2 . GLU E 4 269 ? 173.203 185.031 169.066 1.00 75.07  ? 281 GLU A OE2 1 
ATOM 8113 N N   . SER E 4 270 ? 168.245 186.163 169.173 1.00 76.30  ? 282 SER A N   1 
ATOM 8114 C CA  . SER E 4 270 ? 166.915 185.564 169.151 1.00 76.30  ? 282 SER A CA  1 
ATOM 8115 C C   . SER E 4 270 ? 165.938 186.496 168.449 1.00 76.30  ? 282 SER A C   1 
ATOM 8116 O O   . SER E 4 270 ? 164.720 186.377 168.610 1.00 76.30  ? 282 SER A O   1 
ATOM 8117 C CB  . SER E 4 270 ? 166.433 185.236 170.566 1.00 76.30  ? 282 SER A CB  1 
ATOM 8118 O OG  . SER E 4 270 ? 165.022 185.123 170.609 1.00 76.30  ? 282 SER A OG  1 
ATOM 8119 N N   . THR E 4 271 ? 166.476 187.432 167.672 1.00 71.73  ? 283 THR A N   1 
ATOM 8120 C CA  . THR E 4 271 ? 165.671 188.340 166.876 1.00 71.73  ? 283 THR A CA  1 
ATOM 8121 C C   . THR E 4 271 ? 166.192 188.477 165.453 1.00 71.73  ? 283 THR A C   1 
ATOM 8122 O O   . THR E 4 271 ? 165.468 188.995 164.600 1.00 71.73  ? 283 THR A O   1 
ATOM 8123 C CB  . THR E 4 271 ? 165.610 189.728 167.539 1.00 71.73  ? 283 THR A CB  1 
ATOM 8124 O OG1 . THR E 4 271 ? 164.559 190.500 166.949 1.00 71.73  ? 283 THR A OG1 1 
ATOM 8125 C CG2 . THR E 4 271 ? 166.924 190.462 167.355 1.00 71.73  ? 283 THR A CG2 1 
ATOM 8126 N N   . GLN E 4 272 ? 167.412 188.014 165.167 1.00 71.35  ? 284 GLN A N   1 
ATOM 8127 C CA  . GLN E 4 272 ? 167.949 188.089 163.813 1.00 71.35  ? 284 GLN A CA  1 
ATOM 8128 C C   . GLN E 4 272 ? 167.092 187.296 162.837 1.00 71.35  ? 284 GLN A C   1 
ATOM 8129 O O   . GLN E 4 272 ? 166.791 187.762 161.734 1.00 71.35  ? 284 GLN A O   1 
ATOM 8130 C CB  . GLN E 4 272 ? 169.390 187.577 163.792 1.00 71.35  ? 284 GLN A CB  1 
ATOM 8131 C CG  . GLN E 4 272 ? 170.421 188.573 164.274 1.00 71.35  ? 284 GLN A CG  1 
ATOM 8132 C CD  . GLN E 4 272 ? 171.253 189.128 163.139 1.00 71.35  ? 284 GLN A CD  1 
ATOM 8133 O OE1 . GLN E 4 272 ? 170.786 189.228 162.005 1.00 71.35  ? 284 GLN A OE1 1 
ATOM 8134 N NE2 . GLN E 4 272 ? 172.497 189.487 163.435 1.00 71.35  ? 284 GLN A NE2 1 
ATOM 8135 N N   . ASP E 4 273 ? 166.683 186.093 163.231 1.00 79.64  ? 285 ASP A N   1 
ATOM 8136 C CA  . ASP E 4 273 ? 165.921 185.225 162.343 1.00 79.64  ? 285 ASP A CA  1 
ATOM 8137 C C   . ASP E 4 273 ? 164.441 185.572 162.391 1.00 79.64  ? 285 ASP A C   1 
ATOM 8138 O O   . ASP E 4 273 ? 163.627 184.949 161.703 1.00 79.64  ? 285 ASP A O   1 
ATOM 8139 C CB  . ASP E 4 273 ? 166.137 183.756 162.711 1.00 79.64  ? 285 ASP A CB  1 
ATOM 8140 C CG  . ASP E 4 273 ? 167.462 183.221 162.208 1.00 79.64  ? 285 ASP A CG  1 
ATOM 8141 O OD1 . ASP E 4 273 ? 168.491 183.452 162.876 1.00 79.64  ? 285 ASP A OD1 1 
ATOM 8142 O OD2 . ASP E 4 273 ? 167.474 182.571 161.141 1.00 79.64  ? 285 ASP A OD2 1 
ATOM 8143 N N   . GLU E 4 274 ? 164.082 186.568 163.204 1.00 71.13  ? 286 GLU A N   1 
ATOM 8144 C CA  . GLU E 4 274 ? 162.664 186.924 163.297 1.00 71.13  ? 286 GLU A CA  1 
ATOM 8145 C C   . GLU E 4 274 ? 162.442 188.409 163.023 1.00 71.13  ? 286 GLU A C   1 
ATOM 8146 O O   . GLU E 4 274 ? 161.343 188.768 162.595 1.00 71.13  ? 286 GLU A O   1 
ATOM 8147 C CB  . GLU E 4 274 ? 162.144 186.419 164.666 1.00 71.13  ? 286 GLU A CB  1 
ATOM 8148 C CG  . GLU E 4 274 ? 160.625 186.408 164.949 1.00 71.13  ? 286 GLU A CG  1 
ATOM 8149 C CD  . GLU E 4 274 ? 159.954 187.765 165.021 1.00 71.13  ? 286 GLU A CD  1 
ATOM 8150 O OE1 . GLU E 4 274 ? 160.657 188.790 165.061 1.00 71.13  ? 286 GLU A OE1 1 
ATOM 8151 O OE2 . GLU E 4 274 ? 158.705 187.806 165.036 1.00 71.13  ? 286 GLU A OE2 1 
ATOM 8152 N N   . LEU E 4 275 ? 163.446 189.271 163.185 1.00 67.57  ? 287 LEU A N   1 
ATOM 8153 C CA  . LEU E 4 275 ? 163.327 190.648 162.721 1.00 67.57  ? 287 LEU A CA  1 
ATOM 8154 C C   . LEU E 4 275 ? 163.528 190.706 161.214 1.00 67.57  ? 287 LEU A C   1 
ATOM 8155 O O   . LEU E 4 275 ? 162.851 191.472 160.521 1.00 67.57  ? 287 LEU A O   1 
ATOM 8156 C CB  . LEU E 4 275 ? 164.338 191.559 163.419 1.00 67.57  ? 287 LEU A CB  1 
ATOM 8157 C CG  . LEU E 4 275 ? 164.586 192.932 162.791 1.00 67.57  ? 287 LEU A CG  1 
ATOM 8158 C CD1 . LEU E 4 275 ? 163.327 193.778 162.805 1.00 67.57  ? 287 LEU A CD1 1 
ATOM 8159 C CD2 . LEU E 4 275 ? 165.725 193.650 163.494 1.00 67.57  ? 287 LEU A CD2 1 
ATOM 8160 N N   . ALA E 4 276 ? 164.458 189.901 160.700 1.00 71.48  ? 288 ALA A N   1 
ATOM 8161 C CA  . ALA E 4 276 ? 164.752 189.898 159.273 1.00 71.48  ? 288 ALA A CA  1 
ATOM 8162 C C   . ALA E 4 276 ? 163.533 189.481 158.464 1.00 71.48  ? 288 ALA A C   1 
ATOM 8163 O O   . ALA E 4 276 ? 163.242 190.085 157.426 1.00 71.48  ? 288 ALA A O   1 
ATOM 8164 C CB  . ALA E 4 276 ? 165.932 188.977 158.960 1.00 71.48  ? 288 ALA A CB  1 
ATOM 8165 N N   . ARG E 4 277 ? 162.811 188.454 158.920 1.00 71.91  ? 289 ARG A N   1 
ATOM 8166 C CA  . ARG E 4 277 ? 161.616 188.036 158.199 1.00 71.91  ? 289 ARG A CA  1 
ATOM 8167 C C   . ARG E 4 277 ? 160.578 189.152 158.188 1.00 71.91  ? 289 ARG A C   1 
ATOM 8168 O O   . ARG E 4 277 ? 160.096 189.549 157.123 1.00 71.91  ? 289 ARG A O   1 
ATOM 8169 C CB  . ARG E 4 277 ? 161.040 186.746 158.790 1.00 71.91  ? 289 ARG A CB  1 
ATOM 8170 C CG  . ARG E 4 277 ? 160.782 186.773 160.279 1.00 71.91  ? 289 ARG A CG  1 
ATOM 8171 C CD  . ARG E 4 277 ? 159.953 185.579 160.717 1.00 71.91  ? 289 ARG A CD  1 
ATOM 8172 N NE  . ARG E 4 277 ? 158.859 185.308 159.791 1.00 71.91  ? 289 ARG A NE  1 
ATOM 8173 C CZ  . ARG E 4 277 ? 157.769 186.055 159.677 1.00 71.91  ? 289 ARG A CZ  1 
ATOM 8174 N NH1 . ARG E 4 277 ? 157.587 187.133 160.422 1.00 71.91  ? 289 ARG A NH1 1 
ATOM 8175 N NH2 . ARG E 4 277 ? 156.837 185.711 158.793 1.00 71.91  ? 289 ARG A NH2 1 
ATOM 8176 N N   . LYS E 4 278 ? 160.255 189.713 159.362 1.00 70.25  ? 290 LYS A N   1 
ATOM 8177 C CA  . LYS E 4 278 ? 159.379 190.885 159.389 1.00 70.25  ? 290 LYS A CA  1 
ATOM 8178 C C   . LYS E 4 278 ? 160.151 192.170 159.136 1.00 70.25  ? 290 LYS A C   1 
ATOM 8179 O O   . LYS E 4 278 ? 159.977 193.186 159.812 1.00 70.25  ? 290 LYS A O   1 
ATOM 8180 C CB  . LYS E 4 278 ? 158.624 190.946 160.714 1.00 70.25  ? 290 LYS A CB  1 
ATOM 8181 C CG  . LYS E 4 278 ? 157.321 191.722 160.625 1.00 70.25  ? 290 LYS A CG  1 
ATOM 8182 C CD  . LYS E 4 278 ? 156.227 191.092 161.468 1.00 70.25  ? 290 LYS A CD  1 
ATOM 8183 C CE  . LYS E 4 278 ? 156.494 191.283 162.948 1.00 70.25  ? 290 LYS A CE  1 
ATOM 8184 N NZ  . LYS E 4 278 ? 155.622 190.428 163.795 1.00 70.25  ? 290 LYS A NZ  1 
ATOM 8185 N N   . CYS E 4 279 ? 161.013 192.106 158.136 1.00 79.46  ? 291 CYS A N   1 
ATOM 8186 C CA  . CYS E 4 279 ? 161.543 193.268 157.439 1.00 79.46  ? 291 CYS A CA  1 
ATOM 8187 C C   . CYS E 4 279 ? 161.654 192.886 155.972 1.00 79.46  ? 291 CYS A C   1 
ATOM 8188 O O   . CYS E 4 279 ? 162.163 193.676 155.167 1.00 79.46  ? 291 CYS A O   1 
ATOM 8189 C CB  . CYS E 4 279 ? 162.900 193.691 158.002 1.00 79.46  ? 291 CYS A CB  1 
ATOM 8190 S SG  . CYS E 4 279 ? 163.181 195.465 158.012 1.00 79.46  ? 291 CYS A SG  1 
ATOM 8191 N N   . GLU E 4 280 ? 161.187 191.688 155.623 1.00 84.27  ? 292 GLU A N   1 
ATOM 8192 C CA  . GLU E 4 280 ? 161.323 191.089 154.314 1.00 84.27  ? 292 GLU A CA  1 
ATOM 8193 C C   . GLU E 4 280 ? 159.984 190.884 153.628 1.00 84.27  ? 292 GLU A C   1 
ATOM 8194 O O   . GLU E 4 280 ? 159.950 190.806 152.396 1.00 84.27  ? 292 GLU A O   1 
ATOM 8195 C CB  . GLU E 4 280 ? 162.044 189.738 154.442 1.00 84.27  ? 292 GLU A CB  1 
ATOM 8196 C CG  . GLU E 4 280 ? 163.478 189.737 153.953 1.00 84.27  ? 292 GLU A CG  1 
ATOM 8197 C CD  . GLU E 4 280 ? 164.027 188.338 153.755 1.00 84.27  ? 292 GLU A CD  1 
ATOM 8198 O OE1 . GLU E 4 280 ? 165.260 188.169 153.855 1.00 84.27  ? 292 GLU A OE1 1 
ATOM 8199 O OE2 . GLU E 4 280 ? 163.234 187.404 153.523 1.00 84.27  ? 292 GLU A OE2 1 
ATOM 8200 N N   . GLN E 4 281 ? 158.885 190.792 154.380 1.00 79.96  ? 293 GLN A N   1 
ATOM 8201 C CA  . GLN E 4 281 ? 157.564 190.797 153.767 1.00 79.96  ? 293 GLN A CA  1 
ATOM 8202 C C   . GLN E 4 281 ? 156.961 192.187 153.908 1.00 79.96  ? 293 GLN A C   1 
ATOM 8203 O O   . GLN E 4 281 ? 155.814 192.426 153.515 1.00 79.96  ? 293 GLN A O   1 
ATOM 8204 C CB  . GLN E 4 281 ? 156.652 189.723 154.379 1.00 79.96  ? 293 GLN A CB  1 
ATOM 8205 C CG  . GLN E 4 281 ? 155.730 190.177 155.509 1.00 79.96  ? 293 GLN A CG  1 
ATOM 8206 C CD  . GLN E 4 281 ? 156.355 190.038 156.873 1.00 79.96  ? 293 GLN A CD  1 
ATOM 8207 O OE1 . GLN E 4 281 ? 157.570 190.052 157.006 1.00 79.96  ? 293 GLN A OE1 1 
ATOM 8208 N NE2 . GLN E 4 281 ? 155.523 189.901 157.898 1.00 79.96  ? 293 GLN A NE2 1 
ATOM 8209 N N   . VAL E 4 282 ? 157.753 193.124 154.425 1.00 77.56  ? 294 VAL A N   1 
ATOM 8210 C CA  . VAL E 4 282 ? 157.326 194.511 154.540 1.00 77.56  ? 294 VAL A CA  1 
ATOM 8211 C C   . VAL E 4 282 ? 158.046 195.330 153.480 1.00 77.56  ? 294 VAL A C   1 
ATOM 8212 O O   . VAL E 4 282 ? 157.653 196.464 153.184 1.00 77.56  ? 294 VAL A O   1 
ATOM 8213 C CB  . VAL E 4 282 ? 157.589 195.073 155.948 1.00 77.56  ? 294 VAL A CB  1 
ATOM 8214 C CG1 . VAL E 4 282 ? 159.010 195.615 156.056 1.00 77.56  ? 294 VAL A CG1 1 
ATOM 8215 C CG2 . VAL E 4 282 ? 156.580 196.157 156.274 1.00 77.56  ? 294 VAL A CG2 1 
ATOM 8216 N N   . LEU E 4 283 ? 159.104 194.765 152.894 1.00 79.27  ? 295 LEU A N   1 
ATOM 8217 C CA  . LEU E 4 283 ? 159.789 195.434 151.800 1.00 79.27  ? 295 LEU A CA  1 
ATOM 8218 C C   . LEU E 4 283 ? 159.607 194.753 150.454 1.00 79.27  ? 295 LEU A C   1 
ATOM 8219 O O   . LEU E 4 283 ? 159.025 195.367 149.555 1.00 79.27  ? 295 LEU A O   1 
ATOM 8220 C CB  . LEU E 4 283 ? 161.293 195.537 152.093 1.00 79.27  ? 295 LEU A CB  1 
ATOM 8221 C CG  . LEU E 4 283 ? 161.772 196.746 152.890 1.00 79.27  ? 295 LEU A CG  1 
ATOM 8222 C CD1 . LEU E 4 283 ? 163.284 196.740 152.986 1.00 79.27  ? 295 LEU A CD1 1 
ATOM 8223 C CD2 . LEU E 4 283 ? 161.284 198.027 152.246 1.00 79.27  ? 295 LEU A CD2 1 
ATOM 8224 N N   . ILE E 4 284 ? 160.055 193.506 150.289 1.00 87.16  ? 296 ILE A N   1 
ATOM 8225 C CA  . ILE E 4 284 ? 159.733 192.771 149.070 1.00 87.16  ? 296 ILE A CA  1 
ATOM 8226 C C   . ILE E 4 284 ? 159.149 191.424 149.483 1.00 87.16  ? 296 ILE A C   1 
ATOM 8227 O O   . ILE E 4 284 ? 159.877 190.431 149.592 1.00 87.16  ? 296 ILE A O   1 
ATOM 8228 C CB  . ILE E 4 284 ? 160.961 192.544 148.151 1.00 87.16  ? 296 ILE A CB  1 
ATOM 8229 C CG1 . ILE E 4 284 ? 161.510 193.799 147.445 1.00 87.16  ? 296 ILE A CG1 1 
ATOM 8230 C CG2 . ILE E 4 284 ? 160.618 191.584 147.013 1.00 87.16  ? 296 ILE A CG2 1 
ATOM 8231 C CD1 . ILE E 4 284 ? 161.824 195.025 148.256 1.00 87.16  ? 296 ILE A CD1 1 
ATOM 8232 N N   . GLU E 4 285 ? 157.852 191.382 149.787 1.00 90.86  ? 297 GLU A N   1 
ATOM 8233 C CA  . GLU E 4 285 ? 157.042 190.187 149.570 1.00 90.86  ? 297 GLU A CA  1 
ATOM 8234 C C   . GLU E 4 285 ? 155.613 190.640 149.311 1.00 90.86  ? 297 GLU A C   1 
ATOM 8235 O O   . GLU E 4 285 ? 154.780 189.877 148.815 1.00 90.86  ? 297 GLU A O   1 
ATOM 8236 C CB  . GLU E 4 285 ? 157.183 189.225 150.761 1.00 90.86  ? 297 GLU A CB  1 
ATOM 8237 C CG  . GLU E 4 285 ? 156.614 187.799 150.624 1.00 90.86  ? 297 GLU A CG  1 
ATOM 8238 C CD  . GLU E 4 285 ? 155.096 187.710 150.634 1.00 90.86  ? 297 GLU A CD  1 
ATOM 8239 O OE1 . GLU E 4 285 ? 154.564 186.637 150.281 1.00 90.86  ? 297 GLU A OE1 1 
ATOM 8240 O OE2 . GLU E 4 285 ? 154.436 188.669 151.086 1.00 90.86  ? 297 GLU A OE2 1 
ATOM 8241 N N   . LYS E 4 286 ? 155.358 191.923 149.548 1.00 87.16  ? 298 LYS A N   1 
ATOM 8242 C CA  . LYS E 4 286 ? 154.015 192.475 149.457 1.00 87.16  ? 298 LYS A CA  1 
ATOM 8243 C C   . LYS E 4 286 ? 154.023 193.541 148.378 1.00 87.16  ? 298 LYS A C   1 
ATOM 8244 O O   . LYS E 4 286 ? 152.990 194.135 148.056 1.00 87.16  ? 298 LYS A O   1 
ATOM 8245 C CB  . LYS E 4 286 ? 153.570 193.050 150.802 1.00 87.16  ? 298 LYS A CB  1 
ATOM 8246 C CG  . LYS E 4 286 ? 152.069 193.008 151.034 1.00 87.16  ? 298 LYS A CG  1 
ATOM 8247 C CD  . LYS E 4 286 ? 151.723 193.363 152.472 1.00 87.16  ? 298 LYS A CD  1 
ATOM 8248 C CE  . LYS E 4 286 ? 152.389 192.420 153.464 1.00 87.16  ? 298 LYS A CE  1 
ATOM 8249 N NZ  . LYS E 4 286 ? 152.245 190.987 153.081 1.00 87.16  ? 298 LYS A NZ  1 
ATOM 8250 N N   . HIS E 4 287 ? 155.208 193.782 147.815 1.00 90.43  ? 299 HIS A N   1 
ATOM 8251 C CA  . HIS E 4 287 ? 155.304 194.603 146.615 1.00 90.43  ? 299 HIS A CA  1 
ATOM 8252 C C   . HIS E 4 287 ? 155.637 193.748 145.399 1.00 90.43  ? 299 HIS A C   1 
ATOM 8253 O O   . HIS E 4 287 ? 156.128 194.283 144.398 1.00 90.43  ? 299 HIS A O   1 
ATOM 8254 C CB  . HIS E 4 287 ? 156.347 195.702 146.805 1.00 90.43  ? 299 HIS A CB  1 
ATOM 8255 C CG  . HIS E 4 287 ? 155.912 196.780 147.745 1.00 90.43  ? 299 HIS A CG  1 
ATOM 8256 N ND1 . HIS E 4 287 ? 155.829 196.587 149.107 1.00 90.43  ? 299 HIS A ND1 1 
ATOM 8257 C CD2 . HIS E 4 287 ? 155.528 198.058 147.520 1.00 90.43  ? 299 HIS A CD2 1 
ATOM 8258 C CE1 . HIS E 4 287 ? 155.413 197.702 149.681 1.00 90.43  ? 299 HIS A CE1 1 
ATOM 8259 N NE2 . HIS E 4 287 ? 155.226 198.610 148.740 1.00 90.43  ? 299 HIS A NE2 1 
ATOM 8260 N N   . LEU E 4 288 ? 155.369 192.443 145.449 1.00 86.89  ? 300 LEU A N   1 
ATOM 8261 C CA  . LEU E 4 288 ? 155.631 191.571 144.315 1.00 86.89  ? 300 LEU A CA  1 
ATOM 8262 C C   . LEU E 4 288 ? 154.501 191.692 143.306 1.00 86.89  ? 300 LEU A C   1 
ATOM 8263 O O   . LEU E 4 288 ? 153.986 190.685 142.810 1.00 86.89  ? 300 LEU A O   1 
ATOM 8264 C CB  . LEU E 4 288 ? 155.782 190.121 144.779 1.00 86.89  ? 300 LEU A CB  1 
ATOM 8265 C CG  . LEU E 4 288 ? 157.199 189.562 144.918 1.00 86.89  ? 300 LEU A CG  1 
ATOM 8266 C CD1 . LEU E 4 288 ? 157.165 188.045 144.894 1.00 86.89  ? 300 LEU A CD1 1 
ATOM 8267 C CD2 . LEU E 4 288 ? 158.108 190.096 143.824 1.00 86.89  ? 300 LEU A CD2 1 
ATOM 8268 N N   . GLU E 4 289 ? 154.114 192.926 142.994 1.00 86.62  ? 301 GLU A N   1 
ATOM 8269 C CA  . GLU E 4 289 ? 153.161 193.175 141.925 1.00 86.62  ? 301 GLU A CA  1 
ATOM 8270 C C   . GLU E 4 289 ? 153.860 193.936 140.812 1.00 86.62  ? 301 GLU A C   1 
ATOM 8271 O O   . GLU E 4 289 ? 153.892 193.474 139.668 1.00 86.62  ? 301 GLU A O   1 
ATOM 8272 C CB  . GLU E 4 289 ? 151.946 193.952 142.438 1.00 86.62  ? 301 GLU A CB  1 
ATOM 8273 C CG  . GLU E 4 289 ? 150.841 194.258 141.403 1.00 86.62  ? 301 GLU A CG  1 
ATOM 8274 C CD  . GLU E 4 289 ? 150.412 193.091 140.501 1.00 86.62  ? 301 GLU A CD  1 
ATOM 8275 O OE1 . GLU E 4 289 ? 150.930 191.958 140.603 1.00 86.62  ? 301 GLU A OE1 1 
ATOM 8276 O OE2 . GLU E 4 289 ? 149.528 193.326 139.651 1.00 86.62  ? 301 GLU A OE2 1 
ATOM 8277 N N   . ILE E 4 290 ? 154.422 195.101 141.128 1.00 84.30  ? 302 ILE A N   1 
ATOM 8278 C CA  . ILE E 4 290 ? 155.359 195.715 140.198 1.00 84.30  ? 302 ILE A CA  1 
ATOM 8279 C C   . ILE E 4 290 ? 156.784 195.303 140.579 1.00 84.30  ? 302 ILE A C   1 
ATOM 8280 O O   . ILE E 4 290 ? 157.569 196.060 141.159 1.00 84.30  ? 302 ILE A O   1 
ATOM 8281 C CB  . ILE E 4 290 ? 155.092 197.240 140.097 1.00 84.30  ? 302 ILE A CB  1 
ATOM 8282 C CG1 . ILE E 4 290 ? 155.790 198.098 141.159 1.00 84.30  ? 302 ILE A CG1 1 
ATOM 8283 C CG2 . ILE E 4 290 ? 153.594 197.514 140.124 1.00 84.30  ? 302 ILE A CG2 1 
ATOM 8284 C CD1 . ILE E 4 290 ? 155.919 199.539 140.758 1.00 84.30  ? 302 ILE A CD1 1 
ATOM 8285 N N   . PHE E 4 291 ? 157.117 194.058 140.255 1.00 87.52  ? 303 PHE A N   1 
ATOM 8286 C CA  . PHE E 4 291 ? 158.492 193.605 140.115 1.00 87.52  ? 303 PHE A CA  1 
ATOM 8287 C C   . PHE E 4 291 ? 158.555 192.778 138.843 1.00 87.52  ? 303 PHE A C   1 
ATOM 8288 O O   . PHE E 4 291 ? 159.534 192.826 138.092 1.00 87.52  ? 303 PHE A O   1 
ATOM 8289 C CB  . PHE E 4 291 ? 158.941 192.797 141.332 1.00 87.52  ? 303 PHE A CB  1 
ATOM 8290 C CG  . PHE E 4 291 ? 159.664 193.611 142.364 1.00 87.52  ? 303 PHE A CG  1 
ATOM 8291 C CD1 . PHE E 4 291 ? 160.886 194.193 142.075 1.00 87.52  ? 303 PHE A CD1 1 
ATOM 8292 C CD2 . PHE E 4 291 ? 159.120 193.802 143.619 1.00 87.52  ? 303 PHE A CD2 1 
ATOM 8293 C CE1 . PHE E 4 291 ? 161.552 194.942 143.022 1.00 87.52  ? 303 PHE A CE1 1 
ATOM 8294 C CE2 . PHE E 4 291 ? 159.779 194.552 144.567 1.00 87.52  ? 303 PHE A CE2 1 
ATOM 8295 C CZ  . PHE E 4 291 ? 160.997 195.122 144.268 1.00 87.52  ? 303 PHE A CZ  1 
ATOM 8296 N N   . HIS E 4 292 ? 157.485 192.020 138.610 1.00 86.95  ? 304 HIS A N   1 
ATOM 8297 C CA  . HIS E 4 292 ? 157.320 191.201 137.419 1.00 86.95  ? 304 HIS A CA  1 
ATOM 8298 C C   . HIS E 4 292 ? 157.108 192.106 136.216 1.00 86.95  ? 304 HIS A C   1 
ATOM 8299 O O   . HIS E 4 292 ? 157.632 191.846 135.128 1.00 86.95  ? 304 HIS A O   1 
ATOM 8300 C CB  . HIS E 4 292 ? 156.138 190.250 137.599 1.00 86.95  ? 304 HIS A CB  1 
ATOM 8301 C CG  . HIS E 4 292 ? 156.292 189.315 138.756 1.00 86.95  ? 304 HIS A CG  1 
ATOM 8302 N ND1 . HIS E 4 292 ? 157.519 188.860 139.189 1.00 86.95  ? 304 HIS A ND1 1 
ATOM 8303 C CD2 . HIS E 4 292 ? 155.374 188.767 139.586 1.00 86.95  ? 304 HIS A CD2 1 
ATOM 8304 C CE1 . HIS E 4 292 ? 157.348 188.062 140.228 1.00 86.95  ? 304 HIS A CE1 1 
ATOM 8305 N NE2 . HIS E 4 292 ? 156.056 187.990 140.490 1.00 86.95  ? 304 HIS A NE2 1 
ATOM 8306 N N   . THR E 4 293 ? 156.326 193.167 136.407 1.00 90.40  ? 305 THR A N   1 
ATOM 8307 C CA  . THR E 4 293 ? 156.110 194.165 135.369 1.00 90.40  ? 305 THR A CA  1 
ATOM 8308 C C   . THR E 4 293 ? 157.431 194.830 135.009 1.00 90.40  ? 305 THR A C   1 
ATOM 8309 O O   . THR E 4 293 ? 157.734 195.030 133.828 1.00 90.40  ? 305 THR A O   1 
ATOM 8310 C CB  . THR E 4 293 ? 155.088 195.206 135.832 1.00 90.40  ? 305 THR A CB  1 
ATOM 8311 O OG1 . THR E 4 293 ? 153.770 194.650 135.756 1.00 90.40  ? 305 THR A OG1 1 
ATOM 8312 C CG2 . THR E 4 293 ? 155.155 196.452 134.963 1.00 90.40  ? 305 THR A CG2 1 
ATOM 8313 N N   . GLU E 4 294 ? 158.232 195.163 136.022 1.00 90.76  ? 306 GLU A N   1 
ATOM 8314 C CA  . GLU E 4 294 ? 159.538 195.759 135.767 1.00 90.76  ? 306 GLU A CA  1 
ATOM 8315 C C   . GLU E 4 294 ? 160.535 194.715 135.277 1.00 90.76  ? 306 GLU A C   1 
ATOM 8316 O O   . GLU E 4 294 ? 161.496 195.047 134.575 1.00 90.76  ? 306 GLU A O   1 
ATOM 8317 C CB  . GLU E 4 294 ? 160.054 196.456 137.027 1.00 90.76  ? 306 GLU A CB  1 
ATOM 8318 C CG  . GLU E 4 294 ? 161.369 197.206 136.842 1.00 90.76  ? 306 GLU A CG  1 
ATOM 8319 C CD  . GLU E 4 294 ? 161.208 198.538 136.125 1.00 90.76  ? 306 GLU A CD  1 
ATOM 8320 O OE1 . GLU E 4 294 ? 160.190 198.739 135.429 1.00 90.76  ? 306 GLU A OE1 1 
ATOM 8321 O OE2 . GLU E 4 294 ? 162.110 199.392 136.257 1.00 90.76  ? 306 GLU A OE2 1 
ATOM 8322 N N   . PHE E 4 295 ? 160.320 193.448 135.636 1.00 87.58  ? 307 PHE A N   1 
ATOM 8323 C CA  . PHE E 4 295 ? 161.164 192.359 135.159 1.00 87.58  ? 307 PHE A CA  1 
ATOM 8324 C C   . PHE E 4 295 ? 161.187 192.304 133.639 1.00 87.58  ? 307 PHE A C   1 
ATOM 8325 O O   . PHE E 4 295 ? 162.252 192.144 133.036 1.00 87.58  ? 307 PHE A O   1 
ATOM 8326 C CB  . PHE E 4 295 ? 160.686 191.018 135.715 1.00 87.58  ? 307 PHE A CB  1 
ATOM 8327 C CG  . PHE E 4 295 ? 161.695 189.917 135.586 1.00 87.58  ? 307 PHE A CG  1 
ATOM 8328 C CD1 . PHE E 4 295 ? 162.922 190.000 136.215 1.00 87.58  ? 307 PHE A CD1 1 
ATOM 8329 C CD2 . PHE E 4 295 ? 161.416 188.796 134.825 1.00 87.58  ? 307 PHE A CD2 1 
ATOM 8330 C CE1 . PHE E 4 295 ? 163.848 188.985 136.089 1.00 87.58  ? 307 PHE A CE1 1 
ATOM 8331 C CE2 . PHE E 4 295 ? 162.338 187.779 134.699 1.00 87.58  ? 307 PHE A CE2 1 
ATOM 8332 C CZ  . PHE E 4 295 ? 163.555 187.873 135.334 1.00 87.58  ? 307 PHE A CZ  1 
ATOM 8333 N N   . GLN E 4 296 ? 160.016 192.426 133.012 1.00 83.94  ? 308 GLN A N   1 
ATOM 8334 C CA  . GLN E 4 296 ? 159.946 192.437 131.558 1.00 83.94  ? 308 GLN A CA  1 
ATOM 8335 C C   . GLN E 4 296 ? 160.741 193.606 130.989 1.00 83.94  ? 308 GLN A C   1 
ATOM 8336 O O   . GLN E 4 296 ? 161.552 193.437 130.074 1.00 83.94  ? 308 GLN A O   1 
ATOM 8337 C CB  . GLN E 4 296 ? 158.486 192.500 131.103 1.00 83.94  ? 308 GLN A CB  1 
ATOM 8338 C CG  . GLN E 4 296 ? 158.319 192.644 129.602 1.00 83.94  ? 308 GLN A CG  1 
ATOM 8339 C CD  . GLN E 4 296 ? 158.897 191.469 128.839 1.00 83.94  ? 308 GLN A CD  1 
ATOM 8340 O OE1 . GLN E 4 296 ? 158.693 190.313 129.210 1.00 83.94  ? 308 GLN A OE1 1 
ATOM 8341 N NE2 . GLN E 4 296 ? 159.626 191.759 127.768 1.00 83.94  ? 308 GLN A NE2 1 
ATOM 8342 N N   . ASN E 4 297 ? 160.530 194.801 131.544 1.00 86.75  ? 309 ASN A N   1 
ATOM 8343 C CA  . ASN E 4 297 ? 161.271 195.977 131.102 1.00 86.75  ? 309 ASN A CA  1 
ATOM 8344 C C   . ASN E 4 297 ? 162.764 195.814 131.362 1.00 86.75  ? 309 ASN A C   1 
ATOM 8345 O O   . ASN E 4 297 ? 163.601 196.280 130.582 1.00 86.75  ? 309 ASN A O   1 
ATOM 8346 C CB  . ASN E 4 297 ? 160.735 197.227 131.803 1.00 86.75  ? 309 ASN A CB  1 
ATOM 8347 C CG  . ASN E 4 297 ? 159.431 197.716 131.208 1.00 86.75  ? 309 ASN A CG  1 
ATOM 8348 O OD1 . ASN E 4 297 ? 159.424 198.450 130.220 1.00 86.75  ? 309 ASN A OD1 1 
ATOM 8349 N ND2 . ASN E 4 297 ? 158.318 197.312 131.808 1.00 86.75  ? 309 ASN A ND2 1 
ATOM 8350 N N   . LEU E 4 298 ? 163.114 195.149 132.462 1.00 85.28  ? 310 LEU A N   1 
ATOM 8351 C CA  . LEU E 4 298 ? 164.512 194.939 132.812 1.00 85.28  ? 310 LEU A CA  1 
ATOM 8352 C C   . LEU E 4 298 ? 165.091 193.748 132.060 1.00 85.28  ? 310 LEU A C   1 
ATOM 8353 O O   . LEU E 4 298 ? 166.212 193.315 132.345 1.00 85.28  ? 310 LEU A O   1 
ATOM 8354 C CB  . LEU E 4 298 ? 164.666 194.736 134.320 1.00 85.28  ? 310 LEU A CB  1 
ATOM 8355 C CG  . LEU E 4 298 ? 164.957 195.989 135.145 1.00 85.28  ? 310 LEU A CG  1 
ATOM 8356 C CD1 . LEU E 4 298 ? 165.428 195.614 136.540 1.00 85.28  ? 310 LEU A CD1 1 
ATOM 8357 C CD2 . LEU E 4 298 ? 165.990 196.856 134.445 1.00 85.28  ? 310 LEU A CD2 1 
ATOM 8358 N N   . LEU E 4 299 ? 164.337 193.210 131.105 1.00 84.63  ? 311 LEU A N   1 
ATOM 8359 C CA  . LEU E 4 299 ? 164.791 192.078 130.312 1.00 84.63  ? 311 LEU A CA  1 
ATOM 8360 C C   . LEU E 4 299 ? 164.997 192.404 128.841 1.00 84.63  ? 311 LEU A C   1 
ATOM 8361 O O   . LEU E 4 299 ? 165.920 191.857 128.234 1.00 84.63  ? 311 LEU A O   1 
ATOM 8362 C CB  . LEU E 4 299 ? 163.801 190.909 130.432 1.00 84.63  ? 311 LEU A CB  1 
ATOM 8363 C CG  . LEU E 4 299 ? 164.343 189.518 130.101 1.00 84.63  ? 311 LEU A CG  1 
ATOM 8364 C CD1 . LEU E 4 299 ? 165.811 189.412 130.475 1.00 84.63  ? 311 LEU A CD1 1 
ATOM 8365 C CD2 . LEU E 4 299 ? 163.533 188.454 130.819 1.00 84.63  ? 311 LEU A CD2 1 
ATOM 8366 N N   . ASP E 4 300 ? 164.171 193.270 128.251 1.00 85.68  ? 312 ASP A N   1 
ATOM 8367 C CA  . ASP E 4 300 ? 164.419 193.735 126.891 1.00 85.68  ? 312 ASP A CA  1 
ATOM 8368 C C   . ASP E 4 300 ? 165.742 194.484 126.832 1.00 85.68  ? 312 ASP A C   1 
ATOM 8369 O O   . ASP E 4 300 ? 166.523 194.308 125.892 1.00 85.68  ? 312 ASP A O   1 
ATOM 8370 C CB  . ASP E 4 300 ? 163.281 194.628 126.390 1.00 85.68  ? 312 ASP A CB  1 
ATOM 8371 C CG  . ASP E 4 300 ? 161.947 193.911 126.349 1.00 85.68  ? 312 ASP A CG  1 
ATOM 8372 O OD1 . ASP E 4 300 ? 161.410 193.578 127.423 1.00 85.68  ? 312 ASP A OD1 1 
ATOM 8373 O OD2 . ASP E 4 300 ? 161.430 193.683 125.236 1.00 85.68  ? 312 ASP A OD2 1 
ATOM 8374 N N   . ALA E 4 301 ? 165.999 195.324 127.831 1.00 90.65  ? 313 ALA A N   1 
ATOM 8375 C CA  . ALA E 4 301 ? 167.294 195.975 127.938 1.00 90.65  ? 313 ALA A CA  1 
ATOM 8376 C C   . ALA E 4 301 ? 168.362 194.953 128.301 1.00 90.65  ? 313 ALA A C   1 
ATOM 8377 O O   . ALA E 4 301 ? 168.075 193.919 128.908 1.00 90.65  ? 313 ALA A O   1 
ATOM 8378 C CB  . ALA E 4 301 ? 167.246 197.089 128.985 1.00 90.65  ? 313 ALA A CB  1 
ATOM 8379 N N   . ASP E 4 302 ? 169.603 195.248 127.920 1.00 97.91  ? 314 ASP A N   1 
ATOM 8380 C CA  . ASP E 4 302 ? 170.716 194.346 128.192 1.00 97.91  ? 314 ASP A CA  1 
ATOM 8381 C C   . ASP E 4 302 ? 171.222 194.481 129.624 1.00 97.91  ? 314 ASP A C   1 
ATOM 8382 O O   . ASP E 4 302 ? 172.330 194.035 129.939 1.00 97.91  ? 314 ASP A O   1 
ATOM 8383 C CB  . ASP E 4 302 ? 171.838 194.570 127.163 1.00 97.91  ? 314 ASP A CB  1 
ATOM 8384 C CG  . ASP E 4 302 ? 172.713 195.794 127.461 1.00 97.91  ? 314 ASP A CG  1 
ATOM 8385 O OD1 . ASP E 4 302 ? 172.445 196.557 128.412 1.00 97.91  ? 314 ASP A OD1 1 
ATOM 8386 O OD2 . ASP E 4 302 ? 173.698 195.992 126.719 1.00 97.91  ? 314 ASP A OD2 1 
ATOM 8387 N N   . LYS E 4 303 ? 170.421 195.102 130.490 1.00 90.41  ? 315 LYS A N   1 
ATOM 8388 C CA  . LYS E 4 303 ? 170.803 195.325 131.878 1.00 90.41  ? 315 LYS A CA  1 
ATOM 8389 C C   . LYS E 4 303 ? 171.119 194.002 132.562 1.00 90.41  ? 315 LYS A C   1 
ATOM 8390 O O   . LYS E 4 303 ? 170.312 193.068 132.520 1.00 90.41  ? 315 LYS A O   1 
ATOM 8391 C CB  . LYS E 4 303 ? 169.688 196.063 132.621 1.00 90.41  ? 315 LYS A CB  1 
ATOM 8392 C CG  . LYS E 4 303 ? 170.179 197.191 133.506 1.00 90.41  ? 315 LYS A CG  1 
ATOM 8393 C CD  . LYS E 4 303 ? 170.053 198.531 132.803 1.00 90.41  ? 315 LYS A CD  1 
ATOM 8394 C CE  . LYS E 4 303 ? 170.986 199.565 133.410 1.00 90.41  ? 315 LYS A CE  1 
ATOM 8395 N NZ  . LYS E 4 303 ? 170.772 200.914 132.819 1.00 90.41  ? 315 LYS A NZ  1 
ATOM 8396 N N   . ASN E 4 304 ? 172.293 193.909 133.195 1.00 92.00  ? 316 ASN A N   1 
ATOM 8397 C CA  . ASN E 4 304 ? 172.692 192.616 133.760 1.00 92.00  ? 316 ASN A CA  1 
ATOM 8398 C C   . ASN E 4 304 ? 173.077 192.700 135.232 1.00 92.00  ? 316 ASN A C   1 
ATOM 8399 O O   . ASN E 4 304 ? 173.197 191.648 135.867 1.00 92.00  ? 316 ASN A O   1 
ATOM 8400 C CB  . ASN E 4 304 ? 173.856 192.030 132.956 1.00 92.00  ? 316 ASN A CB  1 
ATOM 8401 C CG  . ASN E 4 304 ? 173.398 191.346 131.685 1.00 92.00  ? 316 ASN A CG  1 
ATOM 8402 O OD1 . ASN E 4 304 ? 172.207 191.305 131.386 1.00 92.00  ? 316 ASN A OD1 1 
ATOM 8403 N ND2 . ASN E 4 304 ? 174.346 190.803 130.930 1.00 92.00  ? 316 ASN A ND2 1 
ATOM 8404 N N   . GLU E 4 305 ? 173.273 193.890 135.799 1.00 96.78  ? 317 GLU A N   1 
ATOM 8405 C CA  . GLU E 4 305 ? 173.534 194.027 137.222 1.00 96.78  ? 317 GLU A CA  1 
ATOM 8406 C C   . GLU E 4 305 ? 172.273 194.245 138.038 1.00 96.78  ? 317 GLU A C   1 
ATOM 8407 O O   . GLU E 4 305 ? 172.241 193.853 139.210 1.00 96.78  ? 317 GLU A O   1 
ATOM 8408 C CB  . GLU E 4 305 ? 174.504 195.189 137.489 1.00 96.78  ? 317 GLU A CB  1 
ATOM 8409 C CG  . GLU E 4 305 ? 175.970 194.799 137.461 1.00 96.78  ? 317 GLU A CG  1 
ATOM 8410 C CD  . GLU E 4 305 ? 176.615 195.059 136.116 1.00 96.78  ? 317 GLU A CD  1 
ATOM 8411 O OE1 . GLU E 4 305 ? 175.907 194.983 135.091 1.00 96.78  ? 317 GLU A OE1 1 
ATOM 8412 O OE2 . GLU E 4 305 ? 177.832 195.340 136.085 1.00 96.78  ? 317 GLU A OE2 1 
ATOM 8413 N N   . ASP E 4 306 ? 171.239 194.854 137.458 1.00 96.57  ? 318 ASP A N   1 
ATOM 8414 C CA  . ASP E 4 306 ? 169.980 195.029 138.165 1.00 96.57  ? 318 ASP A CA  1 
ATOM 8415 C C   . ASP E 4 306 ? 169.298 193.703 138.461 1.00 96.57  ? 318 ASP A C   1 
ATOM 8416 O O   . ASP E 4 306 ? 168.726 193.545 139.543 1.00 96.57  ? 318 ASP A O   1 
ATOM 8417 C CB  . ASP E 4 306 ? 169.054 195.929 137.352 1.00 96.57  ? 318 ASP A CB  1 
ATOM 8418 C CG  . ASP E 4 306 ? 169.687 197.263 137.034 1.00 96.57  ? 318 ASP A CG  1 
ATOM 8419 O OD1 . ASP E 4 306 ? 170.843 197.273 136.564 1.00 96.57  ? 318 ASP A OD1 1 
ATOM 8420 O OD2 . ASP E 4 306 ? 169.030 198.301 137.248 1.00 96.57  ? 318 ASP A OD2 1 
ATOM 8421 N N   . LEU E 4 307 ? 169.357 192.748 137.532 1.00 84.96  ? 319 LEU A N   1 
ATOM 8422 C CA  . LEU E 4 307 ? 168.749 191.444 137.767 1.00 84.96  ? 319 LEU A CA  1 
ATOM 8423 C C   . LEU E 4 307 ? 169.430 190.708 138.913 1.00 84.96  ? 319 LEU A C   1 
ATOM 8424 O O   . LEU E 4 307 ? 168.764 190.012 139.685 1.00 84.96  ? 319 LEU A O   1 
ATOM 8425 C CB  . LEU E 4 307 ? 168.793 190.606 136.490 1.00 84.96  ? 319 LEU A CB  1 
ATOM 8426 C CG  . LEU E 4 307 ? 168.052 191.196 135.290 1.00 84.96  ? 319 LEU A CG  1 
ATOM 8427 C CD1 . LEU E 4 307 ? 168.255 190.334 134.057 1.00 84.96  ? 319 LEU A CD1 1 
ATOM 8428 C CD2 . LEU E 4 307 ? 166.575 191.349 135.602 1.00 84.96  ? 319 LEU A CD2 1 
ATOM 8429 N N   . GLY E 4 308 ? 170.751 190.848 139.039 1.00 87.29  ? 320 GLY A N   1 
ATOM 8430 C CA  . GLY E 4 308 ? 171.448 190.199 140.139 1.00 87.29  ? 320 GLY A CA  1 
ATOM 8431 C C   . GLY E 4 308 ? 170.974 190.683 141.496 1.00 87.29  ? 320 GLY A C   1 
ATOM 8432 O O   . GLY E 4 308 ? 170.693 189.883 142.392 1.00 87.29  ? 320 GLY A O   1 
ATOM 8433 N N   . ARG E 4 309 ? 170.878 192.005 141.668 1.00 91.80  ? 321 ARG A N   1 
ATOM 8434 C CA  . ARG E 4 309 ? 170.299 192.548 142.892 1.00 91.80  ? 321 ARG A CA  1 
ATOM 8435 C C   . ARG E 4 309 ? 168.836 192.159 143.016 1.00 91.80  ? 321 ARG A C   1 
ATOM 8436 O O   . ARG E 4 309 ? 168.377 191.786 144.102 1.00 91.80  ? 321 ARG A O   1 
ATOM 8437 C CB  . ARG E 4 309 ? 170.424 194.070 142.908 1.00 91.80  ? 321 ARG A CB  1 
ATOM 8438 C CG  . ARG E 4 309 ? 171.782 194.597 142.505 1.00 91.80  ? 321 ARG A CG  1 
ATOM 8439 C CD  . ARG E 4 309 ? 171.827 196.110 142.626 1.00 91.80  ? 321 ARG A CD  1 
ATOM 8440 N NE  . ARG E 4 309 ? 171.928 196.550 144.012 1.00 91.80  ? 321 ARG A NE  1 
ATOM 8441 C CZ  . ARG E 4 309 ? 173.011 196.413 144.766 1.00 91.80  ? 321 ARG A CZ  1 
ATOM 8442 N NH1 . ARG E 4 309 ? 174.121 195.874 144.290 1.00 91.80  ? 321 ARG A NH1 1 
ATOM 8443 N NH2 . ARG E 4 309 ? 172.982 196.835 146.027 1.00 91.80  ? 321 ARG A NH2 1 
ATOM 8444 N N   . MET E 4 310 ? 168.103 192.241 141.906 1.00 84.63  ? 322 MET A N   1 
ATOM 8445 C CA  . MET E 4 310 ? 166.710 191.815 141.867 1.00 84.63  ? 322 MET A CA  1 
ATOM 8446 C C   . MET E 4 310 ? 166.568 190.339 142.208 1.00 84.63  ? 322 MET A C   1 
ATOM 8447 O O   . MET E 4 310 ? 165.698 189.963 143.001 1.00 84.63  ? 322 MET A O   1 
ATOM 8448 C CB  . MET E 4 310 ? 166.143 192.142 140.483 1.00 84.63  ? 322 MET A CB  1 
ATOM 8449 C CG  . MET E 4 310 ? 164.636 192.245 140.330 1.00 84.63  ? 322 MET A CG  1 
ATOM 8450 S SD  . MET E 4 310 ? 163.840 190.669 140.613 1.00 84.63  ? 322 MET A SD  1 
ATOM 8451 C CE  . MET E 4 310 ? 164.626 189.803 139.262 1.00 84.63  ? 322 MET A CE  1 
ATOM 8452 N N   . TYR E 4 311 ? 167.417 189.486 141.639 1.00 80.20  ? 323 TYR A N   1 
ATOM 8453 C CA  . TYR E 4 311 ? 167.342 188.070 141.979 1.00 80.20  ? 323 TYR A CA  1 
ATOM 8454 C C   . TYR E 4 311 ? 167.667 187.847 143.450 1.00 80.20  ? 323 TYR A C   1 
ATOM 8455 O O   . TYR E 4 311 ? 167.052 187.004 144.110 1.00 80.20  ? 323 TYR A O   1 
ATOM 8456 C CB  . TYR E 4 311 ? 168.279 187.254 141.095 1.00 80.20  ? 323 TYR A CB  1 
ATOM 8457 C CG  . TYR E 4 311 ? 168.387 185.813 141.521 1.00 80.20  ? 323 TYR A CG  1 
ATOM 8458 C CD1 . TYR E 4 311 ? 167.278 184.980 141.515 1.00 80.20  ? 323 TYR A CD1 1 
ATOM 8459 C CD2 . TYR E 4 311 ? 169.596 185.292 141.951 1.00 80.20  ? 323 TYR A CD2 1 
ATOM 8460 C CE1 . TYR E 4 311 ? 167.377 183.664 141.910 1.00 80.20  ? 323 TYR A CE1 1 
ATOM 8461 C CE2 . TYR E 4 311 ? 169.704 183.980 142.349 1.00 80.20  ? 323 TYR A CE2 1 
ATOM 8462 C CZ  . TYR E 4 311 ? 168.592 183.170 142.327 1.00 80.20  ? 323 TYR A CZ  1 
ATOM 8463 O OH  . TYR E 4 311 ? 168.693 181.858 142.724 1.00 80.20  ? 323 TYR A OH  1 
ATOM 8464 N N   . ASN E 4 312 ? 168.634 188.600 143.981 1.00 83.83  ? 324 ASN A N   1 
ATOM 8465 C CA  . ASN E 4 312 ? 169.017 188.439 145.380 1.00 83.83  ? 324 ASN A CA  1 
ATOM 8466 C C   . ASN E 4 312 ? 167.865 188.789 146.315 1.00 83.83  ? 324 ASN A C   1 
ATOM 8467 O O   . ASN E 4 312 ? 167.650 188.108 147.325 1.00 83.83  ? 324 ASN A O   1 
ATOM 8468 C CB  . ASN E 4 312 ? 170.239 189.302 145.690 1.00 83.83  ? 324 ASN A CB  1 
ATOM 8469 C CG  . ASN E 4 312 ? 171.531 188.672 145.212 1.00 83.83  ? 324 ASN A CG  1 
ATOM 8470 O OD1 . ASN E 4 312 ? 171.808 187.506 145.491 1.00 83.83  ? 324 ASN A OD1 1 
ATOM 8471 N ND2 . ASN E 4 312 ? 172.328 189.443 144.483 1.00 83.83  ? 324 ASN A ND2 1 
ATOM 8472 N N   . LEU E 4 313 ? 167.123 189.853 146.003 1.00 80.37  ? 325 LEU A N   1 
ATOM 8473 C CA  . LEU E 4 313 ? 165.990 190.248 146.832 1.00 80.37  ? 325 LEU A CA  1 
ATOM 8474 C C   . LEU E 4 313 ? 164.920 189.163 146.858 1.00 80.37  ? 325 LEU A C   1 
ATOM 8475 O O   . LEU E 4 313 ? 164.393 188.812 147.918 1.00 80.37  ? 325 LEU A O   1 
ATOM 8476 C CB  . LEU E 4 313 ? 165.407 191.566 146.322 1.00 80.37  ? 325 LEU A CB  1 
ATOM 8477 C CG  . LEU E 4 313 ? 166.201 192.826 146.658 1.00 80.37  ? 325 LEU A CG  1 
ATOM 8478 C CD1 . LEU E 4 313 ? 165.531 194.054 146.066 1.00 80.37  ? 325 LEU A CD1 1 
ATOM 8479 C CD2 . LEU E 4 313 ? 166.346 192.963 148.161 1.00 80.37  ? 325 LEU A CD2 1 
ATOM 8480 N N   . VAL E 4 314 ? 164.587 188.616 145.686 1.00 75.97  ? 326 VAL A N   1 
ATOM 8481 C CA  . VAL E 4 314 ? 163.567 187.579 145.621 1.00 75.97  ? 326 VAL A CA  1 
ATOM 8482 C C   . VAL E 4 314 ? 164.153 186.214 145.953 1.00 75.97  ? 326 VAL A C   1 
ATOM 8483 O O   . VAL E 4 314 ? 163.408 185.246 146.128 1.00 75.97  ? 326 VAL A O   1 
ATOM 8484 C CB  . VAL E 4 314 ? 162.886 187.592 144.235 1.00 75.97  ? 326 VAL A CB  1 
ATOM 8485 C CG1 . VAL E 4 314 ? 161.593 186.792 144.255 1.00 75.97  ? 326 VAL A CG1 1 
ATOM 8486 C CG2 . VAL E 4 314 ? 162.607 189.017 143.801 1.00 75.97  ? 326 VAL A CG2 1 
ATOM 8487 N N   . SER E 4 315 ? 165.480 186.105 146.044 1.00 79.56  ? 327 SER A N   1 
ATOM 8488 C CA  . SER E 4 315 ? 166.076 184.864 146.528 1.00 79.56  ? 327 SER A CA  1 
ATOM 8489 C C   . SER E 4 315 ? 165.695 184.609 147.978 1.00 79.56  ? 327 SER A C   1 
ATOM 8490 O O   . SER E 4 315 ? 165.417 183.469 148.367 1.00 79.56  ? 327 SER A O   1 
ATOM 8491 C CB  . SER E 4 315 ? 167.597 184.911 146.381 1.00 79.56  ? 327 SER A CB  1 
ATOM 8492 O OG  . SER E 4 315 ? 168.188 183.710 146.846 1.00 79.56  ? 327 SER A OG  1 
ATOM 8493 N N   . ARG E 4 316 ? 165.685 185.663 148.794 1.00 84.55  ? 328 ARG A N   1 
ATOM 8494 C CA  . ARG E 4 316 ? 165.330 185.526 150.201 1.00 84.55  ? 328 ARG A CA  1 
ATOM 8495 C C   . ARG E 4 316 ? 163.866 185.129 150.357 1.00 84.55  ? 328 ARG A C   1 
ATOM 8496 O O   . ARG E 4 316 ? 163.505 184.369 151.262 1.00 84.55  ? 328 ARG A O   1 
ATOM 8497 C CB  . ARG E 4 316 ? 165.625 186.835 150.935 1.00 84.55  ? 328 ARG A CB  1 
ATOM 8498 C CG  . ARG E 4 316 ? 166.982 187.433 150.592 1.00 84.55  ? 328 ARG A CG  1 
ATOM 8499 C CD  . ARG E 4 316 ? 167.553 188.234 151.750 1.00 84.55  ? 328 ARG A CD  1 
ATOM 8500 N NE  . ARG E 4 316 ? 168.301 189.408 151.313 1.00 84.55  ? 328 ARG A NE  1 
ATOM 8501 C CZ  . ARG E 4 316 ? 169.451 189.372 150.653 1.00 84.55  ? 328 ARG A CZ  1 
ATOM 8502 N NH1 . ARG E 4 316 ? 170.043 188.228 150.352 1.00 84.55  ? 328 ARG A NH1 1 
ATOM 8503 N NH2 . ARG E 4 316 ? 170.028 190.515 150.295 1.00 84.55  ? 328 ARG A NH2 1 
ATOM 8504 N N   . ILE E 4 317 ? 163.007 185.640 149.475 1.00 90.27  ? 329 ILE A N   1 
ATOM 8505 C CA  . ILE E 4 317 ? 161.582 185.352 149.565 1.00 90.27  ? 329 ILE A CA  1 
ATOM 8506 C C   . ILE E 4 317 ? 161.255 184.090 148.773 1.00 90.27  ? 329 ILE A C   1 
ATOM 8507 O O   . ILE E 4 317 ? 161.722 183.894 147.643 1.00 90.27  ? 329 ILE A O   1 
ATOM 8508 C CB  . ILE E 4 317 ? 160.761 186.558 149.069 1.00 90.27  ? 329 ILE A CB  1 
ATOM 8509 C CG1 . ILE E 4 317 ? 160.308 187.425 150.241 1.00 90.27  ? 329 ILE A CG1 1 
ATOM 8510 C CG2 . ILE E 4 317 ? 159.556 186.122 148.262 1.00 90.27  ? 329 ILE A CG2 1 
ATOM 8511 C CD1 . ILE E 4 317 ? 161.431 187.937 151.094 1.00 90.27  ? 329 ILE A CD1 1 
ATOM 8512 N N   . GLN E 4 318 ? 160.458 183.216 149.373 1.00 104.59 ? 330 GLN A N   1 
ATOM 8513 C CA  . GLN E 4 318 ? 159.954 182.053 148.661 1.00 104.59 ? 330 GLN A CA  1 
ATOM 8514 C C   . GLN E 4 318 ? 158.578 182.366 148.080 1.00 104.59 ? 330 GLN A C   1 
ATOM 8515 O O   . GLN E 4 318 ? 158.007 183.432 148.317 1.00 104.59 ? 330 GLN A O   1 
ATOM 8516 C CB  . GLN E 4 318 ? 159.889 180.837 149.583 1.00 104.59 ? 330 GLN A CB  1 
ATOM 8517 C CG  . GLN E 4 318 ? 158.818 180.940 150.648 1.00 104.59 ? 330 GLN A CG  1 
ATOM 8518 C CD  . GLN E 4 318 ? 159.371 180.860 152.057 1.00 104.59 ? 330 GLN A CD  1 
ATOM 8519 O OE1 . GLN E 4 318 ? 160.209 181.668 152.457 1.00 104.59 ? 330 GLN A OE1 1 
ATOM 8520 N NE2 . GLN E 4 318 ? 158.890 179.890 152.824 1.00 104.59 ? 330 GLN A NE2 1 
ATOM 8521 N N   . ASP E 4 319 ? 158.042 181.415 147.311 1.00 113.03 ? 331 ASP A N   1 
ATOM 8522 C CA  . ASP E 4 319 ? 156.731 181.587 146.691 1.00 113.03 ? 331 ASP A CA  1 
ATOM 8523 C C   . ASP E 4 319 ? 156.719 182.812 145.782 1.00 113.03 ? 331 ASP A C   1 
ATOM 8524 O O   . ASP E 4 319 ? 156.051 183.807 146.078 1.00 113.03 ? 331 ASP A O   1 
ATOM 8525 C CB  . ASP E 4 319 ? 155.633 181.688 147.756 1.00 113.03 ? 331 ASP A CB  1 
ATOM 8526 C CG  . ASP E 4 319 ? 154.236 181.627 147.167 1.00 113.03 ? 331 ASP A CG  1 
ATOM 8527 O OD1 . ASP E 4 319 ? 154.108 181.500 145.931 1.00 113.03 ? 331 ASP A OD1 1 
ATOM 8528 O OD2 . ASP E 4 319 ? 153.262 181.702 147.944 1.00 113.03 ? 331 ASP A OD2 1 
ATOM 8529 N N   . GLY E 4 320 ? 157.458 182.748 144.679 1.00 100.94 ? 332 GLY A N   1 
ATOM 8530 C CA  . GLY E 4 320 ? 157.615 183.890 143.800 1.00 100.94 ? 332 GLY A CA  1 
ATOM 8531 C C   . GLY E 4 320 ? 158.964 183.909 143.115 1.00 100.94 ? 332 GLY A C   1 
ATOM 8532 O O   . GLY E 4 320 ? 159.182 184.676 142.173 1.00 100.94 ? 332 GLY A O   1 
ATOM 8533 N N   . LEU E 4 321 ? 159.882 183.065 143.582 1.00 90.34  ? 333 LEU A N   1 
ATOM 8534 C CA  . LEU E 4 321 ? 161.089 182.772 142.823 1.00 90.34  ? 333 LEU A CA  1 
ATOM 8535 C C   . LEU E 4 321 ? 160.712 181.987 141.574 1.00 90.34  ? 333 LEU A C   1 
ATOM 8536 O O   . LEU E 4 321 ? 161.415 182.041 140.559 1.00 90.34  ? 333 LEU A O   1 
ATOM 8537 C CB  . LEU E 4 321 ? 162.091 181.990 143.674 1.00 90.34  ? 333 LEU A CB  1 
ATOM 8538 C CG  . LEU E 4 321 ? 163.533 181.932 143.165 1.00 90.34  ? 333 LEU A CG  1 
ATOM 8539 C CD1 . LEU E 4 321 ? 163.895 183.205 142.419 1.00 90.34  ? 333 LEU A CD1 1 
ATOM 8540 C CD2 . LEU E 4 321 ? 164.507 181.676 144.309 1.00 90.34  ? 333 LEU A CD2 1 
ATOM 8541 N N   . GLY E 4 322 ? 159.610 181.242 141.650 1.00 95.18  ? 334 GLY A N   1 
ATOM 8542 C CA  . GLY E 4 322 ? 159.126 180.456 140.532 1.00 95.18  ? 334 GLY A CA  1 
ATOM 8543 C C   . GLY E 4 322 ? 158.125 181.167 139.642 1.00 95.18  ? 334 GLY A C   1 
ATOM 8544 O O   . GLY E 4 322 ? 157.642 180.587 138.666 1.00 95.18  ? 334 GLY A O   1 
ATOM 8545 N N   . GLU E 4 323 ? 157.803 182.419 139.958 1.00 91.61  ? 335 GLU A N   1 
ATOM 8546 C CA  . GLU E 4 323 ? 156.937 183.224 139.106 1.00 91.61  ? 335 GLU A CA  1 
ATOM 8547 C C   . GLU E 4 323 ? 157.731 184.009 138.079 1.00 91.61  ? 335 GLU A C   1 
ATOM 8548 O O   . GLU E 4 323 ? 157.351 184.050 136.904 1.00 91.61  ? 335 GLU A O   1 
ATOM 8549 C CB  . GLU E 4 323 ? 156.087 184.179 139.960 1.00 91.61  ? 335 GLU A CB  1 
ATOM 8550 C CG  . GLU E 4 323 ? 155.242 185.162 139.155 1.00 91.61  ? 335 GLU A CG  1 
ATOM 8551 C CD  . GLU E 4 323 ? 154.503 184.510 137.999 1.00 91.61  ? 335 GLU A CD  1 
ATOM 8552 O OE1 . GLU E 4 323 ? 153.775 183.525 138.237 1.00 91.61  ? 335 GLU A OE1 1 
ATOM 8553 O OE2 . GLU E 4 323 ? 154.649 184.984 136.853 1.00 91.61  ? 335 GLU A OE2 1 
ATOM 8554 N N   . LEU E 4 324 ? 158.837 184.618 138.486 1.00 92.62  ? 336 LEU A N   1 
ATOM 8555 C CA  . LEU E 4 324 ? 159.760 185.256 137.556 1.00 92.62  ? 336 LEU A CA  1 
ATOM 8556 C C   . LEU E 4 324 ? 160.723 184.255 136.923 1.00 92.62  ? 336 LEU A C   1 
ATOM 8557 O O   . LEU E 4 324 ? 161.923 184.490 136.772 1.00 92.62  ? 336 LEU A O   1 
ATOM 8558 C CB  . LEU E 4 324 ? 160.472 186.373 138.316 1.00 92.62  ? 336 LEU A CB  1 
ATOM 8559 C CG  . LEU E 4 324 ? 161.804 186.237 139.046 1.00 92.62  ? 336 LEU A CG  1 
ATOM 8560 C CD1 . LEU E 4 324 ? 162.173 187.585 139.539 1.00 92.62  ? 336 LEU A CD1 1 
ATOM 8561 C CD2 . LEU E 4 324 ? 161.700 185.258 140.190 1.00 92.62  ? 336 LEU A CD2 1 
ATOM 8562 N N   . LYS E 4 325 ? 160.156 183.144 136.459 1.00 84.85  ? 337 LYS A N   1 
ATOM 8563 C CA  . LYS E 4 325 ? 160.875 182.017 135.886 1.00 84.85  ? 337 LYS A CA  1 
ATOM 8564 C C   . LYS E 4 325 ? 160.218 181.619 134.574 1.00 84.85  ? 337 LYS A C   1 
ATOM 8565 O O   . LYS E 4 325 ? 160.865 181.053 133.686 1.00 84.85  ? 337 LYS A O   1 
ATOM 8566 C CB  . LYS E 4 325 ? 160.883 180.842 136.869 1.00 84.85  ? 337 LYS A CB  1 
ATOM 8567 C CG  . LYS E 4 325 ? 161.098 179.471 136.264 1.00 84.85  ? 337 LYS A CG  1 
ATOM 8568 C CD  . LYS E 4 325 ? 161.406 178.460 137.355 1.00 84.85  ? 337 LYS A CD  1 
ATOM 8569 C CE  . LYS E 4 325 ? 162.602 178.877 138.190 1.00 84.85  ? 337 LYS A CE  1 
ATOM 8570 N NZ  . LYS E 4 325 ? 163.316 177.703 138.754 1.00 84.85  ? 337 LYS A NZ  1 
ATOM 8571 N N   . LYS E 4 326 ? 158.936 181.948 134.437 1.00 85.01  ? 338 LYS A N   1 
ATOM 8572 C CA  . LYS E 4 326 ? 158.168 181.705 133.228 1.00 85.01  ? 338 LYS A CA  1 
ATOM 8573 C C   . LYS E 4 326 ? 158.350 182.875 132.273 1.00 85.01  ? 338 LYS A C   1 
ATOM 8574 O O   . LYS E 4 326 ? 158.422 182.687 131.055 1.00 85.01  ? 338 LYS A O   1 
ATOM 8575 C CB  . LYS E 4 326 ? 156.690 181.516 133.571 1.00 85.01  ? 338 LYS A CB  1 
ATOM 8576 C CG  . LYS E 4 326 ? 155.868 180.826 132.500 1.00 85.01  ? 338 LYS A CG  1 
ATOM 8577 C CD  . LYS E 4 326 ? 154.725 180.041 133.128 1.00 85.01  ? 338 LYS A CD  1 
ATOM 8578 C CE  . LYS E 4 326 ? 155.217 179.165 134.270 1.00 85.01  ? 338 LYS A CE  1 
ATOM 8579 N NZ  . LYS E 4 326 ? 154.095 178.534 135.020 1.00 85.01  ? 338 LYS A NZ  1 
ATOM 8580 N N   . LEU E 4 327 ? 158.430 184.086 132.825 1.00 82.87  ? 339 LEU A N   1 
ATOM 8581 C CA  . LEU E 4 327 ? 158.602 185.290 132.022 1.00 82.87  ? 339 LEU A CA  1 
ATOM 8582 C C   . LEU E 4 327 ? 159.908 185.237 131.243 1.00 82.87  ? 339 LEU A C   1 
ATOM 8583 O O   . LEU E 4 327 ? 159.938 185.553 130.049 1.00 82.87  ? 339 LEU A O   1 
ATOM 8584 C CB  . LEU E 4 327 ? 158.563 186.537 132.907 1.00 82.87  ? 339 LEU A CB  1 
ATOM 8585 C CG  . LEU E 4 327 ? 157.213 187.242 133.052 1.00 82.87  ? 339 LEU A CG  1 
ATOM 8586 C CD1 . LEU E 4 327 ? 156.828 187.927 131.750 1.00 82.87  ? 339 LEU A CD1 1 
ATOM 8587 C CD2 . LEU E 4 327 ? 156.129 186.272 133.495 1.00 82.87  ? 339 LEU A CD2 1 
ATOM 8588 N N   . LEU E 4 328 ? 160.994 184.841 131.909 1.00 80.77  ? 340 LEU A N   1 
ATOM 8589 C CA  . LEU E 4 328 ? 162.259 184.653 131.207 1.00 80.77  ? 340 LEU A CA  1 
ATOM 8590 C C   . LEU E 4 328 ? 162.154 183.506 130.211 1.00 80.77  ? 340 LEU A C   1 
ATOM 8591 O O   . LEU E 4 328 ? 162.696 183.578 129.102 1.00 80.77  ? 340 LEU A O   1 
ATOM 8592 C CB  . LEU E 4 328 ? 163.387 184.403 132.208 1.00 80.77  ? 340 LEU A CB  1 
ATOM 8593 C CG  . LEU E 4 328 ? 164.712 183.896 131.637 1.00 80.77  ? 340 LEU A CG  1 
ATOM 8594 C CD1 . LEU E 4 328 ? 165.544 185.048 131.110 1.00 80.77  ? 340 LEU A CD1 1 
ATOM 8595 C CD2 . LEU E 4 328 ? 165.480 183.125 132.693 1.00 80.77  ? 340 LEU A CD2 1 
ATOM 8596 N N   . GLU E 4 329 ? 161.452 182.442 130.593 1.00 84.48  ? 341 GLU A N   1 
ATOM 8597 C CA  . GLU E 4 329 ? 161.215 181.304 129.714 1.00 84.48  ? 341 GLU A CA  1 
ATOM 8598 C C   . GLU E 4 329 ? 160.362 181.747 128.533 1.00 84.48  ? 341 GLU A C   1 
ATOM 8599 O O   . GLU E 4 329 ? 160.467 181.184 127.440 1.00 84.48  ? 341 GLU A O   1 
ATOM 8600 C CB  . GLU E 4 329 ? 160.590 180.154 130.529 1.00 84.48  ? 341 GLU A CB  1 
ATOM 8601 C CG  . GLU E 4 329 ? 159.949 178.953 129.799 1.00 84.48  ? 341 GLU A CG  1 
ATOM 8602 C CD  . GLU E 4 329 ? 158.705 179.255 128.973 1.00 84.48  ? 341 GLU A CD  1 
ATOM 8603 O OE1 . GLU E 4 329 ? 158.283 178.362 128.211 1.00 84.48  ? 341 GLU A OE1 1 
ATOM 8604 O OE2 . GLU E 4 329 ? 158.097 180.332 129.138 1.00 84.48  ? 341 GLU A OE2 1 
ATOM 8605 N N   . THR E 4 330 ? 159.517 182.756 128.741 1.00 79.04  ? 342 THR A N   1 
ATOM 8606 C CA  . THR E 4 330 ? 158.645 183.267 127.689 1.00 79.04  ? 342 THR A CA  1 
ATOM 8607 C C   . THR E 4 330 ? 159.180 184.595 127.166 1.00 79.04  ? 342 THR A C   1 
ATOM 8608 O O   . THR E 4 330 ? 158.424 185.460 126.713 1.00 79.04  ? 342 THR A O   1 
ATOM 8609 C CB  . THR E 4 330 ? 157.204 183.415 128.180 1.00 79.04  ? 342 THR A CB  1 
ATOM 8610 O OG1 . THR E 4 330 ? 156.898 182.344 129.081 1.00 79.04  ? 342 THR A OG1 1 
ATOM 8611 C CG2 . THR E 4 330 ? 156.230 183.347 127.010 1.00 79.04  ? 342 THR A CG2 1 
ATOM 8612 N N   . HIS E 4 331 ? 160.499 184.779 127.237 1.00 75.29  ? 343 HIS A N   1 
ATOM 8613 C CA  . HIS E 4 331 ? 161.152 185.907 126.590 1.00 75.29  ? 343 HIS A CA  1 
ATOM 8614 C C   . HIS E 4 331 ? 162.171 185.488 125.545 1.00 75.29  ? 343 HIS A C   1 
ATOM 8615 O O   . HIS E 4 331 ? 162.264 186.143 124.504 1.00 75.29  ? 343 HIS A O   1 
ATOM 8616 C CB  . HIS E 4 331 ? 161.849 186.803 127.624 1.00 75.29  ? 343 HIS A CB  1 
ATOM 8617 C CG  . HIS E 4 331 ? 162.867 187.727 127.029 1.00 75.29  ? 343 HIS A CG  1 
ATOM 8618 N ND1 . HIS E 4 331 ? 162.540 188.965 126.520 1.00 75.29  ? 343 HIS A ND1 1 
ATOM 8619 C CD2 . HIS E 4 331 ? 164.203 187.592 126.861 1.00 75.29  ? 343 HIS A CD2 1 
ATOM 8620 C CE1 . HIS E 4 331 ? 163.631 189.553 126.064 1.00 75.29  ? 343 HIS A CE1 1 
ATOM 8621 N NE2 . HIS E 4 331 ? 164.654 188.741 126.259 1.00 75.29  ? 343 HIS A NE2 1 
ATOM 8622 N N   . ILE E 4 332 ? 162.930 184.420 125.794 1.00 77.12  ? 344 ILE A N   1 
ATOM 8623 C CA  . ILE E 4 332 ? 163.834 183.902 124.775 1.00 77.12  ? 344 ILE A CA  1 
ATOM 8624 C C   . ILE E 4 332 ? 163.046 183.365 123.590 1.00 77.12  ? 344 ILE A C   1 
ATOM 8625 O O   . ILE E 4 332 ? 163.502 183.432 122.444 1.00 77.12  ? 344 ILE A O   1 
ATOM 8626 C CB  . ILE E 4 332 ? 164.754 182.825 125.375 1.00 77.12  ? 344 ILE A CB  1 
ATOM 8627 C CG1 . ILE E 4 332 ? 163.977 181.953 126.360 1.00 77.12  ? 344 ILE A CG1 1 
ATOM 8628 C CG2 . ILE E 4 332 ? 165.948 183.463 126.058 1.00 77.12  ? 344 ILE A CG2 1 
ATOM 8629 C CD1 . ILE E 4 332 ? 164.834 180.936 127.073 1.00 77.12  ? 344 ILE A CD1 1 
ATOM 8630 N N   . HIS E 4 333 ? 161.854 182.831 123.846 1.00 80.04  ? 345 HIS A N   1 
ATOM 8631 C CA  . HIS E 4 333 ? 161.014 182.277 122.793 1.00 80.04  ? 345 HIS A CA  1 
ATOM 8632 C C   . HIS E 4 333 ? 160.476 183.413 121.932 1.00 80.04  ? 345 HIS A C   1 
ATOM 8633 O O   . HIS E 4 333 ? 160.309 183.256 120.719 1.00 80.04  ? 345 HIS A O   1 
ATOM 8634 C CB  . HIS E 4 333 ? 159.883 181.450 123.412 1.00 80.04  ? 345 HIS A CB  1 
ATOM 8635 C CG  . HIS E 4 333 ? 159.106 180.634 122.426 1.00 80.04  ? 345 HIS A CG  1 
ATOM 8636 N ND1 . HIS E 4 333 ? 158.510 179.439 122.764 1.00 80.04  ? 345 HIS A ND1 1 
ATOM 8637 C CD2 . HIS E 4 333 ? 158.820 180.838 121.119 1.00 80.04  ? 345 HIS A CD2 1 
ATOM 8638 C CE1 . HIS E 4 333 ? 157.894 178.940 121.707 1.00 80.04  ? 345 HIS A CE1 1 
ATOM 8639 N NE2 . HIS E 4 333 ? 158.067 179.771 120.696 1.00 80.04  ? 345 HIS A NE2 1 
ATOM 8640 N N   . ASN E 4 334 ? 160.240 184.573 122.542 1.00 76.33  ? 346 ASN A N   1 
ATOM 8641 C CA  . ASN E 4 334 ? 159.827 185.748 121.785 1.00 76.33  ? 346 ASN A CA  1 
ATOM 8642 C C   . ASN E 4 334 ? 161.059 186.501 121.306 1.00 76.33  ? 346 ASN A C   1 
ATOM 8643 O O   . ASN E 4 334 ? 160.951 187.521 120.619 1.00 76.33  ? 346 ASN A O   1 
ATOM 8644 C CB  . ASN E 4 334 ? 158.931 186.654 122.630 1.00 76.33  ? 346 ASN A CB  1 
ATOM 8645 C CG  . ASN E 4 334 ? 157.735 185.921 123.197 1.00 76.33  ? 346 ASN A CG  1 
ATOM 8646 O OD1 . ASN E 4 334 ? 157.880 185.000 123.999 1.00 76.33  ? 346 ASN A OD1 1 
ATOM 8647 N ND2 . ASN E 4 334 ? 156.542 186.326 122.780 1.00 76.33  ? 346 ASN A ND2 1 
ATOM 8648 N N   . GLN E 4 335 ? 162.237 185.998 121.674 1.00 75.75  ? 347 GLN A N   1 
ATOM 8649 C CA  . GLN E 4 335 ? 163.498 186.481 121.141 1.00 75.75  ? 347 GLN A CA  1 
ATOM 8650 C C   . GLN E 4 335 ? 164.116 185.518 120.141 1.00 75.75  ? 347 GLN A C   1 
ATOM 8651 O O   . GLN E 4 335 ? 164.759 185.970 119.186 1.00 75.75  ? 347 GLN A O   1 
ATOM 8652 C CB  . GLN E 4 335 ? 164.497 186.740 122.281 1.00 75.75  ? 347 GLN A CB  1 
ATOM 8653 C CG  . GLN E 4 335 ? 165.942 186.908 121.844 1.00 75.75  ? 347 GLN A CG  1 
ATOM 8654 C CD  . GLN E 4 335 ? 166.199 188.249 121.193 1.00 75.75  ? 347 GLN A CD  1 
ATOM 8655 O OE1 . GLN E 4 335 ? 165.361 189.148 121.244 1.00 75.75  ? 347 GLN A OE1 1 
ATOM 8656 N NE2 . GLN E 4 335 ? 167.364 188.391 120.573 1.00 75.75  ? 347 GLN A NE2 1 
ATOM 8657 N N   . GLY E 4 336 ? 163.913 184.215 120.310 1.00 82.06  ? 348 GLY A N   1 
ATOM 8658 C CA  . GLY E 4 336 ? 164.410 183.239 119.365 1.00 82.06  ? 348 GLY A CA  1 
ATOM 8659 C C   . GLY E 4 336 ? 163.769 183.363 118.001 1.00 82.06  ? 348 GLY A C   1 
ATOM 8660 O O   . GLY E 4 336 ? 164.467 183.356 116.983 1.00 82.06  ? 348 GLY A O   1 
ATOM 8661 N N   . LEU E 4 337 ? 162.442 183.490 117.956 1.00 80.84  ? 349 LEU A N   1 
ATOM 8662 C CA  . LEU E 4 337 ? 161.783 183.696 116.674 1.00 80.84  ? 349 LEU A CA  1 
ATOM 8663 C C   . LEU E 4 337 ? 161.782 185.175 116.319 1.00 80.84  ? 349 LEU A C   1 
ATOM 8664 O O   . LEU E 4 337 ? 160.750 185.731 115.930 1.00 80.84  ? 349 LEU A O   1 
ATOM 8665 C CB  . LEU E 4 337 ? 160.350 183.162 116.699 1.00 80.84  ? 349 LEU A CB  1 
ATOM 8666 C CG  . LEU E 4 337 ? 160.086 181.834 117.406 1.00 80.84  ? 349 LEU A CG  1 
ATOM 8667 C CD1 . LEU E 4 337 ? 158.663 181.802 117.931 1.00 80.84  ? 349 LEU A CD1 1 
ATOM 8668 C CD2 . LEU E 4 337 ? 160.338 180.672 116.468 1.00 80.84  ? 349 LEU A CD2 1 
ATOM 8669 N N   . ALA E 4 338 ? 162.938 185.818 116.459 1.00 88.69  ? 350 ALA A N   1 
ATOM 8670 C CA  . ALA E 4 338 ? 163.161 187.154 115.930 1.00 88.69  ? 350 ALA A CA  1 
ATOM 8671 C C   . ALA E 4 338 ? 164.483 187.158 115.178 1.00 88.69  ? 350 ALA A C   1 
ATOM 8672 O O   . ALA E 4 338 ? 164.621 187.810 114.139 1.00 88.69  ? 350 ALA A O   1 
ATOM 8673 C CB  . ALA E 4 338 ? 163.160 188.196 117.049 1.00 88.69  ? 350 ALA A CB  1 
ATOM 8674 N N   . ALA E 4 339 ? 165.458 186.417 115.708 1.00 92.12  ? 351 ALA A N   1 
ATOM 8675 C CA  . ALA E 4 339 ? 166.759 186.319 115.060 1.00 92.12  ? 351 ALA A CA  1 
ATOM 8676 C C   . ALA E 4 339 ? 166.691 185.434 113.821 1.00 92.12  ? 351 ALA A C   1 
ATOM 8677 O O   . ALA E 4 339 ? 167.264 185.762 112.776 1.00 92.12  ? 351 ALA A O   1 
ATOM 8678 C CB  . ALA E 4 339 ? 167.795 185.788 116.052 1.00 92.12  ? 351 ALA A CB  1 
ATOM 8679 N N   . ILE E 4 340 ? 165.988 184.305 113.917 1.00 94.25  ? 352 ILE A N   1 
ATOM 8680 C CA  . ILE E 4 340 ? 165.858 183.399 112.781 1.00 94.25  ? 352 ILE A CA  1 
ATOM 8681 C C   . ILE E 4 340 ? 164.839 183.983 111.816 1.00 94.25  ? 352 ILE A C   1 
ATOM 8682 O O   . ILE E 4 340 ? 164.763 183.578 110.651 1.00 94.25  ? 352 ILE A O   1 
ATOM 8683 C CB  . ILE E 4 340 ? 165.461 181.977 113.221 1.00 94.25  ? 352 ILE A CB  1 
ATOM 8684 C CG1 . ILE E 4 340 ? 163.974 181.911 113.564 1.00 94.25  ? 352 ILE A CG1 1 
ATOM 8685 C CG2 . ILE E 4 340 ? 166.301 181.531 114.403 1.00 94.25  ? 352 ILE A CG2 1 
ATOM 8686 C CD1 . ILE E 4 340 ? 163.438 180.501 113.635 1.00 94.25  ? 352 ILE A CD1 1 
ATOM 8687 N N   . GLU E 4 341 ? 164.045 184.935 112.297 1.00 100.51 ? 353 GLU A N   1 
ATOM 8688 C CA  . GLU E 4 341 ? 163.190 185.746 111.443 1.00 100.51 ? 353 GLU A CA  1 
ATOM 8689 C C   . GLU E 4 341 ? 163.975 186.791 110.671 1.00 100.51 ? 353 GLU A C   1 
ATOM 8690 O O   . GLU E 4 341 ? 163.701 187.019 109.491 1.00 100.51 ? 353 GLU A O   1 
ATOM 8691 C CB  . GLU E 4 341 ? 162.105 186.434 112.284 1.00 100.51 ? 353 GLU A CB  1 
ATOM 8692 C CG  . GLU E 4 341 ? 161.403 187.648 111.654 1.00 100.51 ? 353 GLU A CG  1 
ATOM 8693 C CD  . GLU E 4 341 ? 160.741 187.394 110.297 1.00 100.51 ? 353 GLU A CD  1 
ATOM 8694 O OE1 . GLU E 4 341 ? 160.939 186.330 109.673 1.00 100.51 ? 353 GLU A OE1 1 
ATOM 8695 O OE2 . GLU E 4 341 ? 160.006 188.295 109.842 1.00 100.51 ? 353 GLU A OE2 1 
ATOM 8696 N N   . LYS E 4 342 ? 164.965 187.419 111.310 1.00 106.43 ? 354 LYS A N   1 
ATOM 8697 C CA  . LYS E 4 342 ? 165.880 188.313 110.614 1.00 106.43 ? 354 LYS A CA  1 
ATOM 8698 C C   . LYS E 4 342 ? 166.881 187.561 109.750 1.00 106.43 ? 354 LYS A C   1 
ATOM 8699 O O   . LYS E 4 342 ? 167.597 188.196 108.968 1.00 106.43 ? 354 LYS A O   1 
ATOM 8700 C CB  . LYS E 4 342 ? 166.625 189.190 111.621 1.00 106.43 ? 354 LYS A CB  1 
ATOM 8701 C CG  . LYS E 4 342 ? 165.836 190.398 112.102 1.00 106.43 ? 354 LYS A CG  1 
ATOM 8702 C CD  . LYS E 4 342 ? 166.631 191.211 113.112 1.00 106.43 ? 354 LYS A CD  1 
ATOM 8703 C CE  . LYS E 4 342 ? 168.119 191.181 112.799 1.00 106.43 ? 354 LYS A CE  1 
ATOM 8704 N NZ  . LYS E 4 342 ? 168.950 191.502 113.990 1.00 106.43 ? 354 LYS A NZ  1 
ATOM 8705 N N   . CYS E 4 343 ? 166.954 186.233 109.879 1.00 113.54 ? 355 CYS A N   1 
ATOM 8706 C CA  . CYS E 4 343 ? 167.819 185.437 109.017 1.00 113.54 ? 355 CYS A CA  1 
ATOM 8707 C C   . CYS E 4 343 ? 167.434 185.620 107.555 1.00 113.54 ? 355 CYS A C   1 
ATOM 8708 O O   . CYS E 4 343 ? 168.292 185.632 106.666 1.00 113.54 ? 355 CYS A O   1 
ATOM 8709 C CB  . CYS E 4 343 ? 167.743 183.962 109.420 1.00 113.54 ? 355 CYS A CB  1 
ATOM 8710 S SG  . CYS E 4 343 ? 169.282 183.040 109.199 1.00 113.54 ? 355 CYS A SG  1 
ATOM 8711 N N   . GLY E 4 344 ? 166.138 185.765 107.293 1.00 114.22 ? 356 GLY A N   1 
ATOM 8712 C CA  . GLY E 4 344 ? 165.665 186.084 105.962 1.00 114.22 ? 356 GLY A CA  1 
ATOM 8713 C C   . GLY E 4 344 ? 165.103 184.897 105.211 1.00 114.22 ? 356 GLY A C   1 
ATOM 8714 O O   . GLY E 4 344 ? 164.279 184.145 105.740 1.00 114.22 ? 356 GLY A O   1 
ATOM 8715 N N   . GLU E 4 345 ? 165.551 184.718 103.971 1.00 116.51 ? 357 GLU A N   1 
ATOM 8716 C CA  . GLU E 4 345 ? 165.054 183.642 103.126 1.00 116.51 ? 357 GLU A CA  1 
ATOM 8717 C C   . GLU E 4 345 ? 166.196 182.729 102.705 1.00 116.51 ? 357 GLU A C   1 
ATOM 8718 O O   . GLU E 4 345 ? 165.970 181.589 102.287 1.00 116.51 ? 357 GLU A O   1 
ATOM 8719 C CB  . GLU E 4 345 ? 164.342 184.216 101.896 1.00 116.51 ? 357 GLU A CB  1 
ATOM 8720 C CG  . GLU E 4 345 ? 162.805 184.236 101.950 1.00 116.51 ? 357 GLU A CG  1 
ATOM 8721 C CD  . GLU E 4 345 ? 162.146 182.862 102.070 1.00 116.51 ? 357 GLU A CD  1 
ATOM 8722 O OE1 . GLU E 4 345 ? 162.804 181.876 102.459 1.00 116.51 ? 357 GLU A OE1 1 
ATOM 8723 O OE2 . GLU E 4 345 ? 160.938 182.773 101.765 1.00 116.51 ? 357 GLU A OE2 1 
ATOM 8724 N N   . ALA E 4 346 ? 167.428 183.224 102.817 1.00 116.56 ? 358 ALA A N   1 
ATOM 8725 C CA  . ALA E 4 346 ? 168.608 182.453 102.446 1.00 116.56 ? 358 ALA A CA  1 
ATOM 8726 C C   . ALA E 4 346 ? 168.823 181.286 103.399 1.00 116.56 ? 358 ALA A C   1 
ATOM 8727 O O   . ALA E 4 346 ? 169.523 180.325 103.061 1.00 116.56 ? 358 ALA A O   1 
ATOM 8728 C CB  . ALA E 4 346 ? 169.846 183.351 102.421 1.00 116.56 ? 358 ALA A CB  1 
ATOM 8729 N N   . ALA E 4 347 ? 168.219 181.361 104.588 1.00 115.57 ? 359 ALA A N   1 
ATOM 8730 C CA  . ALA E 4 347 ? 168.434 180.352 105.621 1.00 115.57 ? 359 ALA A CA  1 
ATOM 8731 C C   . ALA E 4 347 ? 168.113 178.946 105.129 1.00 115.57 ? 359 ALA A C   1 
ATOM 8732 O O   . ALA E 4 347 ? 168.707 177.965 105.587 1.00 115.57 ? 359 ALA A O   1 
ATOM 8733 C CB  . ALA E 4 347 ? 167.596 180.692 106.856 1.00 115.57 ? 359 ALA A CB  1 
ATOM 8734 N N   . LEU E 4 348 ? 167.168 178.828 104.195 1.00 110.99 ? 360 LEU A N   1 
ATOM 8735 C CA  . LEU E 4 348 ? 166.816 177.530 103.634 1.00 110.99 ? 360 LEU A CA  1 
ATOM 8736 C C   . LEU E 4 348 ? 167.992 176.904 102.896 1.00 110.99 ? 360 LEU A C   1 
ATOM 8737 O O   . LEU E 4 348 ? 168.233 175.699 103.012 1.00 110.99 ? 360 LEU A O   1 
ATOM 8738 C CB  . LEU E 4 348 ? 165.623 177.655 102.686 1.00 110.99 ? 360 LEU A CB  1 
ATOM 8739 C CG  . LEU E 4 348 ? 164.257 177.994 103.279 1.00 110.99 ? 360 LEU A CG  1 
ATOM 8740 C CD1 . LEU E 4 348 ? 163.410 178.701 102.239 1.00 110.99 ? 360 LEU A CD1 1 
ATOM 8741 C CD2 . LEU E 4 348 ? 163.562 176.740 103.779 1.00 110.99 ? 360 LEU A CD2 1 
ATOM 8742 N N   . ASN E 4 349 ? 168.731 177.713 102.137 1.00 112.31 ? 361 ASN A N   1 
ATOM 8743 C CA  . ASN E 4 349 ? 169.828 177.226 101.304 1.00 112.31 ? 361 ASN A CA  1 
ATOM 8744 C C   . ASN E 4 349 ? 171.135 177.888 101.744 1.00 112.31 ? 361 ASN A C   1 
ATOM 8745 O O   . ASN E 4 349 ? 171.960 178.312 100.937 1.00 112.31 ? 361 ASN A O   1 
ATOM 8746 C CB  . ASN E 4 349 ? 169.538 177.475 99.826  1.00 112.31 ? 361 ASN A CB  1 
ATOM 8747 C CG  . ASN E 4 349 ? 168.217 176.872 99.383  1.00 112.31 ? 361 ASN A CG  1 
ATOM 8748 O OD1 . ASN E 4 349 ? 167.153 177.264 99.862  1.00 112.31 ? 361 ASN A OD1 1 
ATOM 8749 N ND2 . ASN E 4 349 ? 168.279 175.917 98.462  1.00 112.31 ? 361 ASN A ND2 1 
ATOM 8750 N N   . ASP E 4 350 ? 171.314 177.978 103.058 1.00 110.50 ? 362 ASP A N   1 
ATOM 8751 C CA  . ASP E 4 350 ? 172.550 178.458 103.660 1.00 110.50 ? 362 ASP A CA  1 
ATOM 8752 C C   . ASP E 4 350 ? 172.694 177.813 105.032 1.00 110.50 ? 362 ASP A C   1 
ATOM 8753 O O   . ASP E 4 350 ? 172.204 178.355 106.031 1.00 110.50 ? 362 ASP A O   1 
ATOM 8754 C CB  . ASP E 4 350 ? 172.567 179.982 103.768 1.00 110.50 ? 362 ASP A CB  1 
ATOM 8755 C CG  . ASP E 4 350 ? 173.967 180.534 103.948 1.00 110.50 ? 362 ASP A CG  1 
ATOM 8756 O OD1 . ASP E 4 350 ? 174.937 179.796 103.677 1.00 110.50 ? 362 ASP A OD1 1 
ATOM 8757 O OD2 . ASP E 4 350 ? 174.099 181.704 104.360 1.00 110.50 ? 362 ASP A OD2 1 
ATOM 8758 N N   . PRO E 4 351 ? 173.360 176.665 105.119 1.00 97.97  ? 363 PRO A N   1 
ATOM 8759 C CA  . PRO E 4 351 ? 173.311 175.860 106.345 1.00 97.97  ? 363 PRO A CA  1 
ATOM 8760 C C   . PRO E 4 351 ? 173.862 176.526 107.598 1.00 97.97  ? 363 PRO A C   1 
ATOM 8761 O O   . PRO E 4 351 ? 173.267 176.394 108.671 1.00 97.97  ? 363 PRO A O   1 
ATOM 8762 C CB  . PRO E 4 351 ? 174.122 174.614 105.949 1.00 97.97  ? 363 PRO A CB  1 
ATOM 8763 C CG  . PRO E 4 351 ? 174.828 175.004 104.605 1.00 97.97  ? 363 PRO A CG  1 
ATOM 8764 C CD  . PRO E 4 351 ? 174.668 176.475 104.482 1.00 97.97  ? 363 PRO A CD  1 
ATOM 8765 N N   . LYS E 4 352 ? 174.992 177.222 107.486 1.00 94.56  ? 364 LYS A N   1 
ATOM 8766 C CA  . LYS E 4 352 ? 175.636 177.836 108.642 1.00 94.56  ? 364 LYS A CA  1 
ATOM 8767 C C   . LYS E 4 352 ? 174.714 178.812 109.364 1.00 94.56  ? 364 LYS A C   1 
ATOM 8768 O O   . LYS E 4 352 ? 174.714 178.872 110.598 1.00 94.56  ? 364 LYS A O   1 
ATOM 8769 C CB  . LYS E 4 352 ? 176.923 178.549 108.223 1.00 94.56  ? 364 LYS A CB  1 
ATOM 8770 C CG  . LYS E 4 352 ? 177.777 179.008 109.395 1.00 94.56  ? 364 LYS A CG  1 
ATOM 8771 C CD  . LYS E 4 352 ? 179.035 179.720 108.926 1.00 94.56  ? 364 LYS A CD  1 
ATOM 8772 C CE  . LYS E 4 352 ? 179.832 178.868 107.952 1.00 94.56  ? 364 LYS A CE  1 
ATOM 8773 N NZ  . LYS E 4 352 ? 180.017 177.475 108.449 1.00 94.56  ? 364 LYS A NZ  1 
ATOM 8774 N N   . MET E 4 353 ? 173.936 179.585 108.607 1.00 97.90  ? 365 MET A N   1 
ATOM 8775 C CA  . MET E 4 353 ? 173.088 180.621 109.185 1.00 97.90  ? 365 MET A CA  1 
ATOM 8776 C C   . MET E 4 353 ? 172.099 180.072 110.204 1.00 97.90  ? 365 MET A C   1 
ATOM 8777 O O   . MET E 4 353 ? 171.934 180.653 111.281 1.00 97.90  ? 365 MET A O   1 
ATOM 8778 C CB  . MET E 4 353 ? 172.332 181.369 108.085 1.00 97.90  ? 365 MET A CB  1 
ATOM 8779 C CG  . MET E 4 353 ? 173.126 182.394 107.253 1.00 97.90  ? 365 MET A CG  1 
ATOM 8780 S SD  . MET E 4 353 ? 174.510 183.304 107.997 1.00 97.90  ? 365 MET A SD  1 
ATOM 8781 C CE  . MET E 4 353 ? 175.867 182.128 107.991 1.00 97.90  ? 365 MET A CE  1 
ATOM 8782 N N   . TYR E 4 354 ? 171.441 178.960 109.887 1.00 90.59  ? 366 TYR A N   1 
ATOM 8783 C CA  . TYR E 4 354 ? 170.416 178.427 110.776 1.00 90.59  ? 366 TYR A CA  1 
ATOM 8784 C C   . TYR E 4 354 ? 171.026 177.854 112.049 1.00 90.59  ? 366 TYR A C   1 
ATOM 8785 O O   . TYR E 4 354 ? 170.314 177.614 113.028 1.00 90.59  ? 366 TYR A O   1 
ATOM 8786 C CB  . TYR E 4 354 ? 169.586 177.359 110.064 1.00 90.59  ? 366 TYR A CB  1 
ATOM 8787 C CG  . TYR E 4 354 ? 168.503 176.763 110.931 1.00 90.59  ? 366 TYR A CG  1 
ATOM 8788 C CD1 . TYR E 4 354 ? 167.374 177.496 111.264 1.00 90.59  ? 366 TYR A CD1 1 
ATOM 8789 C CD2 . TYR E 4 354 ? 168.617 175.474 111.431 1.00 90.59  ? 366 TYR A CD2 1 
ATOM 8790 C CE1 . TYR E 4 354 ? 166.385 176.958 112.060 1.00 90.59  ? 366 TYR A CE1 1 
ATOM 8791 C CE2 . TYR E 4 354 ? 167.632 174.928 112.227 1.00 90.59  ? 366 TYR A CE2 1 
ATOM 8792 C CZ  . TYR E 4 354 ? 166.519 175.674 112.539 1.00 90.59  ? 366 TYR A CZ  1 
ATOM 8793 O OH  . TYR E 4 354 ? 165.534 175.136 113.334 1.00 90.59  ? 366 TYR A OH  1 
ATOM 8794 N N   . VAL E 4 355 ? 172.340 177.639 112.055 1.00 91.10  ? 367 VAL A N   1 
ATOM 8795 C CA  . VAL E 4 355 ? 173.010 177.084 113.225 1.00 91.10  ? 367 VAL A CA  1 
ATOM 8796 C C   . VAL E 4 355 ? 173.646 178.207 114.034 1.00 91.10  ? 367 VAL A C   1 
ATOM 8797 O O   . VAL E 4 355 ? 173.514 178.254 115.262 1.00 91.10  ? 367 VAL A O   1 
ATOM 8798 C CB  . VAL E 4 355 ? 174.059 176.034 112.821 1.00 91.10  ? 367 VAL A CB  1 
ATOM 8799 C CG1 . VAL E 4 355 ? 175.127 175.919 113.892 1.00 91.10  ? 367 VAL A CG1 1 
ATOM 8800 C CG2 . VAL E 4 355 ? 173.393 174.691 112.582 1.00 91.10  ? 367 VAL A CG2 1 
ATOM 8801 N N   . GLN E 4 356 ? 174.343 179.118 113.352 1.00 90.14  ? 368 GLN A N   1 
ATOM 8802 C CA  . GLN E 4 356 ? 174.988 180.231 114.039 1.00 90.14  ? 368 GLN A CA  1 
ATOM 8803 C C   . GLN E 4 356 ? 173.965 181.127 114.728 1.00 90.14  ? 368 GLN A C   1 
ATOM 8804 O O   . GLN E 4 356 ? 174.203 181.631 115.830 1.00 90.14  ? 368 GLN A O   1 
ATOM 8805 C CB  . GLN E 4 356 ? 175.829 181.035 113.045 1.00 90.14  ? 368 GLN A CB  1 
ATOM 8806 C CG  . GLN E 4 356 ? 177.251 180.531 112.887 1.00 90.14  ? 368 GLN A CG  1 
ATOM 8807 C CD  . GLN E 4 356 ? 178.162 181.016 113.995 1.00 90.14  ? 368 GLN A CD  1 
ATOM 8808 O OE1 . GLN E 4 356 ? 177.812 181.924 114.748 1.00 90.14  ? 368 GLN A OE1 1 
ATOM 8809 N NE2 . GLN E 4 356 ? 179.341 180.415 114.097 1.00 90.14  ? 368 GLN A NE2 1 
ATOM 8810 N N   . THR E 4 357 ? 172.816 181.334 114.083 1.00 87.66  ? 369 THR A N   1 
ATOM 8811 C CA  . THR E 4 357 ? 171.811 182.247 114.617 1.00 87.66  ? 369 THR A CA  1 
ATOM 8812 C C   . THR E 4 357 ? 171.262 181.747 115.949 1.00 87.66  ? 369 THR A C   1 
ATOM 8813 O O   . THR E 4 357 ? 171.191 182.499 116.927 1.00 87.66  ? 369 THR A O   1 
ATOM 8814 C CB  . THR E 4 357 ? 170.682 182.424 113.601 1.00 87.66  ? 369 THR A CB  1 
ATOM 8815 O OG1 . THR E 4 357 ? 171.177 183.123 112.453 1.00 87.66  ? 369 THR A OG1 1 
ATOM 8816 C CG2 . THR E 4 357 ? 169.545 183.220 114.203 1.00 87.66  ? 369 THR A CG2 1 
ATOM 8817 N N   . VAL E 4 358 ? 170.883 180.471 116.010 1.00 82.97  ? 370 VAL A N   1 
ATOM 8818 C CA  . VAL E 4 358 ? 170.296 179.907 117.221 1.00 82.97  ? 370 VAL A CA  1 
ATOM 8819 C C   . VAL E 4 358 ? 171.372 179.827 118.295 1.00 82.97  ? 370 VAL A C   1 
ATOM 8820 O O   . VAL E 4 358 ? 171.099 180.042 119.481 1.00 82.97  ? 370 VAL A O   1 
ATOM 8821 C CB  . VAL E 4 358 ? 169.653 178.532 116.958 1.00 82.97  ? 370 VAL A CB  1 
ATOM 8822 C CG1 . VAL E 4 358 ? 170.578 177.647 116.160 1.00 82.97  ? 370 VAL A CG1 1 
ATOM 8823 C CG2 . VAL E 4 358 ? 169.258 177.859 118.264 1.00 82.97  ? 370 VAL A CG2 1 
ATOM 8824 N N   . LEU E 4 359 ? 172.604 179.535 117.885 1.00 87.32  ? 371 LEU A N   1 
ATOM 8825 C CA  . LEU E 4 359 ? 173.733 179.460 118.803 1.00 87.32  ? 371 LEU A CA  1 
ATOM 8826 C C   . LEU E 4 359 ? 174.010 180.792 119.481 1.00 87.32  ? 371 LEU A C   1 
ATOM 8827 O O   . LEU E 4 359 ? 174.409 180.815 120.651 1.00 87.32  ? 371 LEU A O   1 
ATOM 8828 C CB  . LEU E 4 359 ? 174.987 178.980 118.057 1.00 87.32  ? 371 LEU A CB  1 
ATOM 8829 C CG  . LEU E 4 359 ? 175.372 177.512 118.244 1.00 87.32  ? 371 LEU A CG  1 
ATOM 8830 C CD1 . LEU E 4 359 ? 176.767 177.248 117.701 1.00 87.32  ? 371 LEU A CD1 1 
ATOM 8831 C CD2 . LEU E 4 359 ? 175.273 177.108 119.704 1.00 87.32  ? 371 LEU A CD2 1 
ATOM 8832 N N   . ASP E 4 360 ? 173.812 181.906 118.774 1.00 87.79  ? 372 ASP A N   1 
ATOM 8833 C CA  . ASP E 4 360 ? 173.962 183.220 119.388 1.00 87.79  ? 372 ASP A CA  1 
ATOM 8834 C C   . ASP E 4 360 ? 172.915 183.436 120.473 1.00 87.79  ? 372 ASP A C   1 
ATOM 8835 O O   . ASP E 4 360 ? 173.197 184.023 121.523 1.00 87.79  ? 372 ASP A O   1 
ATOM 8836 C CB  . ASP E 4 360 ? 173.869 184.310 118.319 1.00 87.79  ? 372 ASP A CB  1 
ATOM 8837 C CG  . ASP E 4 360 ? 175.229 184.759 117.829 1.00 87.79  ? 372 ASP A CG  1 
ATOM 8838 O OD1 . ASP E 4 360 ? 176.226 184.069 118.129 1.00 87.79  ? 372 ASP A OD1 1 
ATOM 8839 O OD2 . ASP E 4 360 ? 175.303 185.803 117.148 1.00 87.79  ? 372 ASP A OD2 1 
ATOM 8840 N N   . VAL E 4 361 ? 171.691 182.973 120.225 1.00 78.62  ? 373 VAL A N   1 
ATOM 8841 C CA  . VAL E 4 361 ? 170.612 183.071 121.201 1.00 78.62  ? 373 VAL A CA  1 
ATOM 8842 C C   . VAL E 4 361 ? 170.988 182.287 122.449 1.00 78.62  ? 373 VAL A C   1 
ATOM 8843 O O   . VAL E 4 361 ? 170.806 182.769 123.573 1.00 78.62  ? 373 VAL A O   1 
ATOM 8844 C CB  . VAL E 4 361 ? 169.281 182.570 120.617 1.00 78.62  ? 373 VAL A CB  1 
ATOM 8845 C CG1 . VAL E 4 361 ? 168.135 182.928 121.543 1.00 78.62  ? 373 VAL A CG1 1 
ATOM 8846 C CG2 . VAL E 4 361 ? 169.058 183.166 119.240 1.00 78.62  ? 373 VAL A CG2 1 
ATOM 8847 N N   . HIS E 4 362 ? 171.512 181.077 122.269 1.00 80.59  ? 374 HIS A N   1 
ATOM 8848 C CA  . HIS E 4 362 ? 171.999 180.304 123.410 1.00 80.59  ? 374 HIS A CA  1 
ATOM 8849 C C   . HIS E 4 362 ? 173.477 180.553 123.671 1.00 80.59  ? 374 HIS A C   1 
ATOM 8850 O O   . HIS E 4 362 ? 174.256 179.621 123.884 1.00 80.59  ? 374 HIS A O   1 
ATOM 8851 C CB  . HIS E 4 362 ? 171.730 178.821 123.166 1.00 80.59  ? 374 HIS A CB  1 
ATOM 8852 C CG  . HIS E 4 362 ? 172.005 177.948 124.350 1.00 80.59  ? 374 HIS A CG  1 
ATOM 8853 N ND1 . HIS E 4 362 ? 173.113 177.133 124.430 1.00 80.59  ? 374 HIS A ND1 1 
ATOM 8854 C CD2 . HIS E 4 362 ? 171.310 177.752 125.494 1.00 80.59  ? 374 HIS A CD2 1 
ATOM 8855 C CE1 . HIS E 4 362 ? 173.094 176.480 125.578 1.00 80.59  ? 374 HIS A CE1 1 
ATOM 8856 N NE2 . HIS E 4 362 ? 172.010 176.837 126.242 1.00 80.59  ? 374 HIS A NE2 1 
ATOM 8857 N N   . LYS E 4 363 ? 173.894 181.818 123.646 1.00 81.85  ? 375 LYS A N   1 
ATOM 8858 C CA  . LYS E 4 363 ? 175.177 182.222 124.204 1.00 81.85  ? 375 LYS A CA  1 
ATOM 8859 C C   . LYS E 4 363 ? 174.961 183.343 125.209 1.00 81.85  ? 375 LYS A C   1 
ATOM 8860 O O   . LYS E 4 363 ? 175.456 183.291 126.340 1.00 81.85  ? 375 LYS A O   1 
ATOM 8861 C CB  . LYS E 4 363 ? 176.140 182.663 123.101 1.00 81.85  ? 375 LYS A CB  1 
ATOM 8862 C CG  . LYS E 4 363 ? 177.506 183.086 123.616 1.00 81.85  ? 375 LYS A CG  1 
ATOM 8863 C CD  . LYS E 4 363 ? 178.624 182.426 122.829 1.00 81.85  ? 375 LYS A CD  1 
ATOM 8864 C CE  . LYS E 4 363 ? 178.583 182.830 121.366 1.00 81.85  ? 375 LYS A CE  1 
ATOM 8865 N NZ  . LYS E 4 363 ? 178.989 184.248 121.174 1.00 81.85  ? 375 LYS A NZ  1 
ATOM 8866 N N   . LYS E 4 364 ? 174.210 184.360 124.790 1.00 71.86  ? 376 LYS A N   1 
ATOM 8867 C CA  . LYS E 4 364 ? 173.973 185.553 125.589 1.00 71.86  ? 376 LYS A CA  1 
ATOM 8868 C C   . LYS E 4 364 ? 173.069 185.251 126.775 1.00 71.86  ? 376 LYS A C   1 
ATOM 8869 O O   . LYS E 4 364 ? 173.365 185.651 127.905 1.00 71.86  ? 376 LYS A O   1 
ATOM 8870 C CB  . LYS E 4 364 ? 173.369 186.653 124.714 1.00 71.86  ? 376 LYS A CB  1 
ATOM 8871 C CG  . LYS E 4 364 ? 172.554 187.690 125.461 1.00 71.86  ? 376 LYS A CG  1 
ATOM 8872 C CD  . LYS E 4 364 ? 171.651 188.451 124.506 1.00 71.86  ? 376 LYS A CD  1 
ATOM 8873 C CE  . LYS E 4 364 ? 171.244 189.797 125.076 1.00 71.86  ? 376 LYS A CE  1 
ATOM 8874 N NZ  . LYS E 4 364 ? 170.353 189.653 126.259 1.00 71.86  ? 376 LYS A NZ  1 
ATOM 8875 N N   . TYR E 4 365 ? 171.971 184.536 126.533 1.00 73.99  ? 377 TYR A N   1 
ATOM 8876 C CA  . TYR E 4 365 ? 171.034 184.228 127.605 1.00 73.99  ? 377 TYR A CA  1 
ATOM 8877 C C   . TYR E 4 365 ? 171.533 183.059 128.440 1.00 73.99  ? 377 TYR A C   1 
ATOM 8878 O O   . TYR E 4 365 ? 170.948 182.738 129.479 1.00 73.99  ? 377 TYR A O   1 
ATOM 8879 C CB  . TYR E 4 365 ? 169.642 183.941 127.042 1.00 73.99  ? 377 TYR A CB  1 
ATOM 8880 C CG  . TYR E 4 365 ? 168.984 185.164 126.454 1.00 73.99  ? 377 TYR A CG  1 
ATOM 8881 C CD1 . TYR E 4 365 ? 169.244 185.557 125.151 1.00 73.99  ? 377 TYR A CD1 1 
ATOM 8882 C CD2 . TYR E 4 365 ? 168.107 185.930 127.206 1.00 73.99  ? 377 TYR A CD2 1 
ATOM 8883 C CE1 . TYR E 4 365 ? 168.645 186.677 124.611 1.00 73.99  ? 377 TYR A CE1 1 
ATOM 8884 C CE2 . TYR E 4 365 ? 167.505 187.052 126.676 1.00 73.99  ? 377 TYR A CE2 1 
ATOM 8885 C CZ  . TYR E 4 365 ? 167.777 187.421 125.378 1.00 73.99  ? 377 TYR A CZ  1 
ATOM 8886 O OH  . TYR E 4 365 ? 167.178 188.539 124.844 1.00 73.99  ? 377 TYR A OH  1 
ATOM 8887 N N   . ASN E 4 366 ? 172.611 182.416 127.999 1.00 78.43  ? 378 ASN A N   1 
ATOM 8888 C CA  . ASN E 4 366 ? 173.259 181.414 128.832 1.00 78.43  ? 378 ASN A CA  1 
ATOM 8889 C C   . ASN E 4 366 ? 174.023 182.102 129.953 1.00 78.43  ? 378 ASN A C   1 
ATOM 8890 O O   . ASN E 4 366 ? 173.997 181.649 131.101 1.00 78.43  ? 378 ASN A O   1 
ATOM 8891 C CB  . ASN E 4 366 ? 174.195 180.533 128.008 1.00 78.43  ? 378 ASN A CB  1 
ATOM 8892 C CG  . ASN E 4 366 ? 175.125 179.710 128.875 1.00 78.43  ? 378 ASN A CG  1 
ATOM 8893 O OD1 . ASN E 4 366 ? 174.693 178.787 129.564 1.00 78.43  ? 378 ASN A OD1 1 
ATOM 8894 N ND2 . ASN E 4 366 ? 176.410 180.041 128.845 1.00 78.43  ? 378 ASN A ND2 1 
ATOM 8895 N N   . ALA E 4 367 ? 174.706 183.197 129.623 1.00 77.20  ? 379 ALA A N   1 
ATOM 8896 C CA  . ALA E 4 367 ? 175.426 183.985 130.615 1.00 77.20  ? 379 ALA A CA  1 
ATOM 8897 C C   . ALA E 4 367 ? 174.456 184.577 131.629 1.00 77.20  ? 379 ALA A C   1 
ATOM 8898 O O   . ALA E 4 367 ? 174.787 184.710 132.812 1.00 77.20  ? 379 ALA A O   1 
ATOM 8899 C CB  . ALA E 4 367 ? 176.236 185.093 129.940 1.00 77.20  ? 379 ALA A CB  1 
ATOM 8900 N N   . LEU E 4 368 ? 173.257 184.934 131.171 1.00 71.82  ? 380 LEU A N   1 
ATOM 8901 C CA  . LEU E 4 368 ? 172.228 185.478 132.046 1.00 71.82  ? 380 LEU A CA  1 
ATOM 8902 C C   . LEU E 4 368 ? 171.846 184.472 133.121 1.00 71.82  ? 380 LEU A C   1 
ATOM 8903 O O   . LEU E 4 368 ? 171.652 184.840 134.283 1.00 71.82  ? 380 LEU A O   1 
ATOM 8904 C CB  . LEU E 4 368 ? 170.991 185.877 131.241 1.00 71.82  ? 380 LEU A CB  1 
ATOM 8905 C CG  . LEU E 4 368 ? 170.264 187.127 131.728 1.00 71.82  ? 380 LEU A CG  1 
ATOM 8906 C CD1 . LEU E 4 368 ? 171.113 188.350 131.474 1.00 71.82  ? 380 LEU A CD1 1 
ATOM 8907 C CD2 . LEU E 4 368 ? 168.911 187.262 131.053 1.00 71.82  ? 380 LEU A CD2 1 
ATOM 8908 N N   . VAL E 4 369 ? 171.744 183.200 132.744 1.00 76.27  ? 381 VAL A N   1 
ATOM 8909 C CA  . VAL E 4 369 ? 171.336 182.157 133.676 1.00 76.27  ? 381 VAL A CA  1 
ATOM 8910 C C   . VAL E 4 369 ? 172.599 181.638 134.355 1.00 76.27  ? 381 VAL A C   1 
ATOM 8911 O O   . VAL E 4 369 ? 172.551 180.748 135.211 1.00 76.27  ? 381 VAL A O   1 
ATOM 8912 C CB  . VAL E 4 369 ? 170.550 181.052 132.938 1.00 76.27  ? 381 VAL A CB  1 
ATOM 8913 C CG1 . VAL E 4 369 ? 170.137 179.915 133.866 1.00 76.27  ? 381 VAL A CG1 1 
ATOM 8914 C CG2 . VAL E 4 369 ? 169.330 181.645 132.254 1.00 76.27  ? 381 VAL A CG2 1 
ATOM 8915 N N   . MET E 4 370 ? 173.741 182.235 134.019 1.00 83.14  ? 382 MET A N   1 
ATOM 8916 C CA  . MET E 4 370 ? 175.002 181.840 134.633 1.00 83.14  ? 382 MET A CA  1 
ATOM 8917 C C   . MET E 4 370 ? 175.499 182.913 135.593 1.00 83.14  ? 382 MET A C   1 
ATOM 8918 O O   . MET E 4 370 ? 175.759 182.632 136.766 1.00 83.14  ? 382 MET A O   1 
ATOM 8919 C CB  . MET E 4 370 ? 176.060 181.564 133.564 1.00 83.14  ? 382 MET A CB  1 
ATOM 8920 C CG  . MET E 4 370 ? 177.460 181.352 134.119 1.00 83.14  ? 382 MET A CG  1 
ATOM 8921 S SD  . MET E 4 370 ? 178.511 180.369 133.031 1.00 83.14  ? 382 MET A SD  1 
ATOM 8922 C CE  . MET E 4 370 ? 180.138 180.874 133.583 1.00 83.14  ? 382 MET A CE  1 
ATOM 8923 N N   . SER E 4 371 ? 175.627 184.145 135.106 1.00 78.28  ? 383 SER A N   1 
ATOM 8924 C CA  . SER E 4 371 ? 176.149 185.229 135.927 1.00 78.28  ? 383 SER A CA  1 
ATOM 8925 C C   . SER E 4 371 ? 175.069 185.816 136.825 1.00 78.28  ? 383 SER A C   1 
ATOM 8926 O O   . SER E 4 371 ? 175.220 185.841 138.051 1.00 78.28  ? 383 SER A O   1 
ATOM 8927 C CB  . SER E 4 371 ? 176.751 186.325 135.045 1.00 78.28  ? 383 SER A CB  1 
ATOM 8928 O OG  . SER E 4 371 ? 176.814 187.558 135.741 1.00 78.28  ? 383 SER A OG  1 
ATOM 8929 N N   . ALA E 4 372 ? 173.980 186.293 136.225 1.00 77.20  ? 384 ALA A N   1 
ATOM 8930 C CA  . ALA E 4 372 ? 172.943 186.996 136.967 1.00 77.20  ? 384 ALA A CA  1 
ATOM 8931 C C   . ALA E 4 372 ? 172.277 186.111 138.013 1.00 77.20  ? 384 ALA A C   1 
ATOM 8932 O O   . ALA E 4 372 ? 172.384 186.380 139.213 1.00 77.20  ? 384 ALA A O   1 
ATOM 8933 C CB  . ALA E 4 372 ? 171.889 187.554 136.010 1.00 77.20  ? 384 ALA A CB  1 
ATOM 8934 N N   . PHE E 4 373 ? 171.592 185.054 137.578 1.00 76.36  ? 385 PHE A N   1 
ATOM 8935 C CA  . PHE E 4 373 ? 170.821 184.248 138.517 1.00 76.36  ? 385 PHE A CA  1 
ATOM 8936 C C   . PHE E 4 373 ? 171.615 183.060 139.048 1.00 76.36  ? 385 PHE A C   1 
ATOM 8937 O O   . PHE E 4 373 ? 171.114 181.931 139.055 1.00 76.36  ? 385 PHE A O   1 
ATOM 8938 C CB  . PHE E 4 373 ? 169.524 183.760 137.865 1.00 76.36  ? 385 PHE A CB  1 
ATOM 8939 C CG  . PHE E 4 373 ? 168.722 184.850 137.211 1.00 76.36  ? 385 PHE A CG  1 
ATOM 8940 C CD1 . PHE E 4 373 ? 169.013 185.274 135.927 1.00 76.36  ? 385 PHE A CD1 1 
ATOM 8941 C CD2 . PHE E 4 373 ? 167.684 185.461 137.889 1.00 76.36  ? 385 PHE A CD2 1 
ATOM 8942 C CE1 . PHE E 4 373 ? 168.278 186.274 135.329 1.00 76.36  ? 385 PHE A CE1 1 
ATOM 8943 C CE2 . PHE E 4 373 ? 166.943 186.463 137.293 1.00 76.36  ? 385 PHE A CE2 1 
ATOM 8944 C CZ  . PHE E 4 373 ? 167.243 186.870 136.014 1.00 76.36  ? 385 PHE A CZ  1 
ATOM 8945 N N   . ASN E 4 374 ? 172.844 183.317 139.502 1.00 78.88  ? 386 ASN A N   1 
ATOM 8946 C CA  . ASN E 4 374 ? 173.670 182.385 140.268 1.00 78.88  ? 386 ASN A CA  1 
ATOM 8947 C C   . ASN E 4 374 ? 173.587 180.931 139.812 1.00 78.88  ? 386 ASN A C   1 
ATOM 8948 O O   . ASN E 4 374 ? 173.609 180.023 140.649 1.00 78.88  ? 386 ASN A O   1 
ATOM 8949 C CB  . ASN E 4 374 ? 173.298 182.468 141.750 1.00 78.88  ? 386 ASN A CB  1 
ATOM 8950 C CG  . ASN E 4 374 ? 174.512 182.511 142.653 1.00 78.88  ? 386 ASN A CG  1 
ATOM 8951 O OD1 . ASN E 4 374 ? 175.584 182.960 142.248 1.00 78.88  ? 386 ASN A OD1 1 
ATOM 8952 N ND2 . ASN E 4 374 ? 174.350 182.044 143.884 1.00 78.88  ? 386 ASN A ND2 1 
ATOM 8953 N N   . ASN E 4 375 ? 173.513 180.703 138.500 1.00 78.90  ? 387 ASN A N   1 
ATOM 8954 C CA  . ASN E 4 375 ? 173.436 179.359 137.932 1.00 78.90  ? 387 ASN A CA  1 
ATOM 8955 C C   . ASN E 4 375 ? 172.409 178.485 138.641 1.00 78.90  ? 387 ASN A C   1 
ATOM 8956 O O   . ASN E 4 375 ? 172.696 177.327 138.963 1.00 78.90  ? 387 ASN A O   1 
ATOM 8957 C CB  . ASN E 4 375 ? 174.806 178.679 137.970 1.00 78.90  ? 387 ASN A CB  1 
ATOM 8958 C CG  . ASN E 4 375 ? 175.734 179.178 136.884 1.00 78.90  ? 387 ASN A CG  1 
ATOM 8959 O OD1 . ASN E 4 375 ? 176.611 180.004 137.132 1.00 78.90  ? 387 ASN A OD1 1 
ATOM 8960 N ND2 . ASN E 4 375 ? 175.545 178.677 135.669 1.00 78.90  ? 387 ASN A ND2 1 
ATOM 8961 N N   . ASP E 4 376 ? 171.222 179.026 138.899 1.00 84.47  ? 388 ASP A N   1 
ATOM 8962 C CA  . ASP E 4 376 ? 170.184 178.255 139.569 1.00 84.47  ? 388 ASP A CA  1 
ATOM 8963 C C   . ASP E 4 376 ? 169.788 177.066 138.704 1.00 84.47  ? 388 ASP A C   1 
ATOM 8964 O O   . ASP E 4 376 ? 169.600 177.201 137.491 1.00 84.47  ? 388 ASP A O   1 
ATOM 8965 C CB  . ASP E 4 376 ? 168.973 179.145 139.858 1.00 84.47  ? 388 ASP A CB  1 
ATOM 8966 C CG  . ASP E 4 376 ? 167.924 178.463 140.729 1.00 84.47  ? 388 ASP A CG  1 
ATOM 8967 O OD1 . ASP E 4 376 ? 167.727 177.235 140.617 1.00 84.47  ? 388 ASP A OD1 1 
ATOM 8968 O OD2 . ASP E 4 376 ? 167.288 179.170 141.540 1.00 84.47  ? 388 ASP A OD2 1 
ATOM 8969 N N   . ALA E 4 377 ? 169.665 175.898 139.334 1.00 87.58  ? 389 ALA A N   1 
ATOM 8970 C CA  . ALA E 4 377 ? 169.316 174.674 138.624 1.00 87.58  ? 389 ALA A CA  1 
ATOM 8971 C C   . ALA E 4 377 ? 167.953 174.808 137.960 1.00 87.58  ? 389 ALA A C   1 
ATOM 8972 O O   . ALA E 4 377 ? 167.774 174.406 136.805 1.00 87.58  ? 389 ALA A O   1 
ATOM 8973 C CB  . ALA E 4 377 ? 169.329 173.477 139.576 1.00 87.58  ? 389 ALA A CB  1 
ATOM 8974 N N   . GLY E 4 378 ? 166.989 175.368 138.683 1.00 86.32  ? 390 GLY A N   1 
ATOM 8975 C CA  . GLY E 4 378 ? 165.673 175.605 138.128 1.00 86.32  ? 390 GLY A CA  1 
ATOM 8976 C C   . GLY E 4 378 ? 165.680 176.615 137.000 1.00 86.32  ? 390 GLY A C   1 
ATOM 8977 O O   . GLY E 4 378 ? 164.903 176.498 136.049 1.00 86.32  ? 390 GLY A O   1 
ATOM 8978 N N   . PHE E 4 379 ? 166.550 177.622 137.098 1.00 81.65  ? 391 PHE A N   1 
ATOM 8979 C CA  . PHE E 4 379 ? 166.593 178.660 136.073 1.00 81.65  ? 391 PHE A CA  1 
ATOM 8980 C C   . PHE E 4 379 ? 167.250 178.150 134.797 1.00 81.65  ? 391 PHE A C   1 
ATOM 8981 O O   . PHE E 4 379 ? 167.042 178.707 133.713 1.00 81.65  ? 391 PHE A O   1 
ATOM 8982 C CB  . PHE E 4 379 ? 167.319 179.895 136.601 1.00 81.65  ? 391 PHE A CB  1 
ATOM 8983 C CG  . PHE E 4 379 ? 166.400 181.025 136.950 1.00 81.65  ? 391 PHE A CG  1 
ATOM 8984 C CD1 . PHE E 4 379 ? 165.466 180.884 137.959 1.00 81.65  ? 391 PHE A CD1 1 
ATOM 8985 C CD2 . PHE E 4 379 ? 166.466 182.225 136.266 1.00 81.65  ? 391 PHE A CD2 1 
ATOM 8986 C CE1 . PHE E 4 379 ? 164.615 181.919 138.281 1.00 81.65  ? 391 PHE A CE1 1 
ATOM 8987 C CE2 . PHE E 4 379 ? 165.616 183.261 136.582 1.00 81.65  ? 391 PHE A CE2 1 
ATOM 8988 C CZ  . PHE E 4 379 ? 164.691 183.110 137.592 1.00 81.65  ? 391 PHE A CZ  1 
ATOM 8989 N N   . VAL E 4 380 ? 168.060 177.099 134.906 1.00 82.34  ? 392 VAL A N   1 
ATOM 8990 C CA  . VAL E 4 380 ? 168.657 176.470 133.733 1.00 82.34  ? 392 VAL A CA  1 
ATOM 8991 C C   . VAL E 4 380 ? 167.535 175.883 132.888 1.00 82.34  ? 392 VAL A C   1 
ATOM 8992 O O   . VAL E 4 380 ? 167.601 175.890 131.653 1.00 82.34  ? 392 VAL A O   1 
ATOM 8993 C CB  . VAL E 4 380 ? 169.692 175.401 134.130 1.00 82.34  ? 392 VAL A CB  1 
ATOM 8994 C CG1 . VAL E 4 380 ? 170.092 174.563 132.926 1.00 82.34  ? 392 VAL A CG1 1 
ATOM 8995 C CG2 . VAL E 4 380 ? 170.917 176.058 134.741 1.00 82.34  ? 392 VAL A CG2 1 
ATOM 8996 N N   . ALA E 4 381 ? 166.487 175.389 133.551 1.00 85.54  ? 393 ALA A N   1 
ATOM 8997 C CA  . ALA E 4 381 ? 165.331 174.852 132.841 1.00 85.54  ? 393 ALA A CA  1 
ATOM 8998 C C   . ALA E 4 381 ? 164.674 175.910 131.960 1.00 85.54  ? 393 ALA A C   1 
ATOM 8999 O O   . ALA E 4 381 ? 164.026 175.587 130.959 1.00 85.54  ? 393 ALA A O   1 
ATOM 9000 C CB  . ALA E 4 381 ? 164.323 174.278 133.839 1.00 85.54  ? 393 ALA A CB  1 
ATOM 9001 N N   . ALA E 4 382 ? 164.822 177.185 132.326 1.00 82.86  ? 394 ALA A N   1 
ATOM 9002 C CA  . ALA E 4 382 ? 164.348 178.261 131.463 1.00 82.86  ? 394 ALA A CA  1 
ATOM 9003 C C   . ALA E 4 382 ? 165.196 178.355 130.199 1.00 82.86  ? 394 ALA A C   1 
ATOM 9004 O O   . ALA E 4 382 ? 164.670 178.439 129.085 1.00 82.86  ? 394 ALA A O   1 
ATOM 9005 C CB  . ALA E 4 382 ? 164.353 179.587 132.226 1.00 82.86  ? 394 ALA A CB  1 
ATOM 9006 N N   . LEU E 4 383 ? 166.522 178.337 130.358 1.00 81.12  ? 395 LEU A N   1 
ATOM 9007 C CA  . LEU E 4 383 ? 167.415 178.271 129.205 1.00 81.12  ? 395 LEU A CA  1 
ATOM 9008 C C   . LEU E 4 383 ? 167.253 176.955 128.456 1.00 81.12  ? 395 LEU A C   1 
ATOM 9009 O O   . LEU E 4 383 ? 167.628 176.858 127.283 1.00 81.12  ? 395 LEU A O   1 
ATOM 9010 C CB  . LEU E 4 383 ? 168.861 178.451 129.666 1.00 81.12  ? 395 LEU A CB  1 
ATOM 9011 C CG  . LEU E 4 383 ? 169.946 178.520 128.595 1.00 81.12  ? 395 LEU A CG  1 
ATOM 9012 C CD1 . LEU E 4 383 ? 169.799 179.803 127.796 1.00 81.12  ? 395 LEU A CD1 1 
ATOM 9013 C CD2 . LEU E 4 383 ? 171.327 178.413 129.216 1.00 81.12  ? 395 LEU A CD2 1 
ATOM 9014 N N   . ASP E 4 384 ? 166.684 175.951 129.118 1.00 91.09  ? 396 ASP A N   1 
ATOM 9015 C CA  . ASP E 4 384 ? 166.308 174.657 128.563 1.00 91.09  ? 396 ASP A CA  1 
ATOM 9016 C C   . ASP E 4 384 ? 164.996 174.798 127.804 1.00 91.09  ? 396 ASP A C   1 
ATOM 9017 O O   . ASP E 4 384 ? 164.709 175.870 127.262 1.00 91.09  ? 396 ASP A O   1 
ATOM 9018 C CB  . ASP E 4 384 ? 166.205 173.593 129.654 1.00 91.09  ? 396 ASP A CB  1 
ATOM 9019 C CG  . ASP E 4 384 ? 167.403 172.665 129.672 1.00 91.09  ? 396 ASP A CG  1 
ATOM 9020 O OD1 . ASP E 4 384 ? 168.414 172.989 129.014 1.00 91.09  ? 396 ASP A OD1 1 
ATOM 9021 O OD2 . ASP E 4 384 ? 167.336 171.613 130.342 1.00 91.09  ? 396 ASP A OD2 1 
ATOM 9022 N N   . LYS E 4 385 ? 164.203 173.724 127.765 1.00 95.12  ? 397 LYS A N   1 
ATOM 9023 C CA  . LYS E 4 385 ? 163.127 173.448 126.812 1.00 95.12  ? 397 LYS A CA  1 
ATOM 9024 C C   . LYS E 4 385 ? 162.466 174.668 126.173 1.00 95.12  ? 397 LYS A C   1 
ATOM 9025 O O   . LYS E 4 385 ? 161.957 174.563 125.053 1.00 95.12  ? 397 LYS A O   1 
ATOM 9026 C CB  . LYS E 4 385 ? 162.053 172.604 127.509 1.00 95.12  ? 397 LYS A CB  1 
ATOM 9027 C CG  . LYS E 4 385 ? 161.043 173.418 128.313 1.00 95.12  ? 397 LYS A CG  1 
ATOM 9028 C CD  . LYS E 4 385 ? 159.810 172.613 128.680 1.00 95.12  ? 397 LYS A CD  1 
ATOM 9029 C CE  . LYS E 4 385 ? 158.727 173.515 129.252 1.00 95.12  ? 397 LYS A CE  1 
ATOM 9030 N NZ  . LYS E 4 385 ? 159.134 174.115 130.553 1.00 95.12  ? 397 LYS A NZ  1 
ATOM 9031 N N   . ALA E 4 386 ? 162.410 175.805 126.867 1.00 92.02  ? 398 ALA A N   1 
ATOM 9032 C CA  . ALA E 4 386 ? 162.015 177.040 126.199 1.00 92.02  ? 398 ALA A CA  1 
ATOM 9033 C C   . ALA E 4 386 ? 162.870 177.253 124.954 1.00 92.02  ? 398 ALA A C   1 
ATOM 9034 O O   . ALA E 4 386 ? 162.386 177.771 123.943 1.00 92.02  ? 398 ALA A O   1 
ATOM 9035 C CB  . ALA E 4 386 ? 162.143 178.235 127.141 1.00 92.02  ? 398 ALA A CB  1 
ATOM 9036 N N   . CYS E 4 387 ? 164.142 176.858 125.019 1.00 94.66  ? 399 CYS A N   1 
ATOM 9037 C CA  . CYS E 4 387 ? 164.995 176.822 123.837 1.00 94.66  ? 399 CYS A CA  1 
ATOM 9038 C C   . CYS E 4 387 ? 164.563 175.711 122.887 1.00 94.66  ? 399 CYS A C   1 
ATOM 9039 O O   . CYS E 4 387 ? 164.751 175.814 121.672 1.00 94.66  ? 399 CYS A O   1 
ATOM 9040 C CB  . CYS E 4 387 ? 166.462 176.641 124.231 1.00 94.66  ? 399 CYS A CB  1 
ATOM 9041 S SG  . CYS E 4 387 ? 167.394 178.181 124.369 1.00 94.66  ? 399 CYS A SG  1 
ATOM 9042 N N   . GLY E 4 388 ? 164.014 174.630 123.431 1.00 93.65  ? 400 GLY A N   1 
ATOM 9043 C CA  . GLY E 4 388 ? 163.504 173.554 122.605 1.00 93.65  ? 400 GLY A CA  1 
ATOM 9044 C C   . GLY E 4 388 ? 162.311 173.963 121.766 1.00 93.65  ? 400 GLY A C   1 
ATOM 9045 O O   . GLY E 4 388 ? 162.125 173.463 120.653 1.00 93.65  ? 400 GLY A O   1 
ATOM 9046 N N   . ARG E 4 389 ? 161.493 174.877 122.290 1.00 92.27  ? 401 ARG A N   1 
ATOM 9047 C CA  . ARG E 4 389 ? 160.240 175.239 121.637 1.00 92.27  ? 401 ARG A CA  1 
ATOM 9048 C C   . ARG E 4 389 ? 160.432 176.310 120.569 1.00 92.27  ? 401 ARG A C   1 
ATOM 9049 O O   . ARG E 4 389 ? 159.456 176.766 119.965 1.00 92.27  ? 401 ARG A O   1 
ATOM 9050 C CB  . ARG E 4 389 ? 159.212 175.690 122.678 1.00 92.27  ? 401 ARG A CB  1 
ATOM 9051 C CG  . ARG E 4 389 ? 158.860 174.592 123.671 1.00 92.27  ? 401 ARG A CG  1 
ATOM 9052 C CD  . ARG E 4 389 ? 158.070 175.087 124.876 1.00 92.27  ? 401 ARG A CD  1 
ATOM 9053 N NE  . ARG E 4 389 ? 158.165 176.525 125.096 1.00 92.27  ? 401 ARG A NE  1 
ATOM 9054 C CZ  . ARG E 4 389 ? 157.157 177.373 124.942 1.00 92.27  ? 401 ARG A CZ  1 
ATOM 9055 N NH1 . ARG E 4 389 ? 155.971 176.968 124.519 1.00 92.27  ? 401 ARG A NH1 1 
ATOM 9056 N NH2 . ARG E 4 389 ? 157.340 178.658 125.231 1.00 92.27  ? 401 ARG A NH2 1 
ATOM 9057 N N   . PHE E 4 390 ? 161.679 176.722 120.324 1.00 89.99  ? 402 PHE A N   1 
ATOM 9058 C CA  . PHE E 4 390 ? 161.973 177.494 119.122 1.00 89.99  ? 402 PHE A CA  1 
ATOM 9059 C C   . PHE E 4 390 ? 163.029 176.806 118.263 1.00 89.99  ? 402 PHE A C   1 
ATOM 9060 O O   . PHE E 4 390 ? 163.648 177.463 117.417 1.00 89.99  ? 402 PHE A O   1 
ATOM 9061 C CB  . PHE E 4 390 ? 162.386 178.943 119.464 1.00 89.99  ? 402 PHE A CB  1 
ATOM 9062 C CG  . PHE E 4 390 ? 163.857 179.135 119.715 1.00 89.99  ? 402 PHE A CG  1 
ATOM 9063 C CD1 . PHE E 4 390 ? 164.460 178.605 120.836 1.00 89.99  ? 402 PHE A CD1 1 
ATOM 9064 C CD2 . PHE E 4 390 ? 164.632 179.864 118.829 1.00 89.99  ? 402 PHE A CD2 1 
ATOM 9065 C CE1 . PHE E 4 390 ? 165.810 178.787 121.065 1.00 89.99  ? 402 PHE A CE1 1 
ATOM 9066 C CE2 . PHE E 4 390 ? 165.979 180.048 119.053 1.00 89.99  ? 402 PHE A CE2 1 
ATOM 9067 C CZ  . PHE E 4 390 ? 166.568 179.510 120.173 1.00 89.99  ? 402 PHE A CZ  1 
ATOM 9068 N N   . ILE E 4 391 ? 163.240 175.502 118.441 1.00 94.67  ? 403 ILE A N   1 
ATOM 9069 C CA  . ILE E 4 391 ? 164.087 174.712 117.562 1.00 94.67  ? 403 ILE A CA  1 
ATOM 9070 C C   . ILE E 4 391 ? 163.309 173.590 116.887 1.00 94.67  ? 403 ILE A C   1 
ATOM 9071 O O   . ILE E 4 391 ? 163.735 173.070 115.850 1.00 94.67  ? 403 ILE A O   1 
ATOM 9072 C CB  . ILE E 4 391 ? 165.307 174.147 118.322 1.00 94.67  ? 403 ILE A CB  1 
ATOM 9073 C CG1 . ILE E 4 391 ? 166.483 173.942 117.367 1.00 94.67  ? 403 ILE A CG1 1 
ATOM 9074 C CG2 . ILE E 4 391 ? 164.953 172.850 119.028 1.00 94.67  ? 403 ILE A CG2 1 
ATOM 9075 C CD1 . ILE E 4 391 ? 167.008 175.221 116.765 1.00 94.67  ? 403 ILE A CD1 1 
ATOM 9076 N N   . ASN E 4 392 ? 162.167 173.200 117.455 1.00 104.01 ? 404 ASN A N   1 
ATOM 9077 C CA  . ASN E 4 392 ? 161.352 172.130 116.893 1.00 104.01 ? 404 ASN A CA  1 
ATOM 9078 C C   . ASN E 4 392 ? 160.323 172.670 115.908 1.00 104.01 ? 404 ASN A C   1 
ATOM 9079 O O   . ASN E 4 392 ? 160.321 172.297 114.731 1.00 104.01 ? 404 ASN A O   1 
ATOM 9080 C CB  . ASN E 4 392 ? 160.647 171.359 118.010 1.00 104.01 ? 404 ASN A CB  1 
ATOM 9081 C CG  . ASN E 4 392 ? 161.617 170.676 118.945 1.00 104.01 ? 404 ASN A CG  1 
ATOM 9082 O OD1 . ASN E 4 392 ? 162.643 170.156 118.517 1.00 104.01 ? 404 ASN A OD1 1 
ATOM 9083 N ND2 . ASN E 4 392 ? 161.295 170.672 120.233 1.00 104.01 ? 404 ASN A ND2 1 
ATOM 9084 N N   . ASN E 4 393 ? 159.444 173.551 116.386 1.00 105.07 ? 405 ASN A N   1 
ATOM 9085 C CA  . ASN E 4 393 ? 158.345 174.070 115.581 1.00 105.07 ? 405 ASN A CA  1 
ATOM 9086 C C   . ASN E 4 393 ? 158.554 175.529 115.191 1.00 105.07 ? 405 ASN A C   1 
ATOM 9087 O O   . ASN E 4 393 ? 157.591 176.259 114.933 1.00 105.07 ? 405 ASN A O   1 
ATOM 9088 C CB  . ASN E 4 393 ? 157.017 173.832 116.325 1.00 105.07 ? 405 ASN A CB  1 
ATOM 9089 C CG  . ASN E 4 393 ? 156.772 174.798 117.498 1.00 105.07 ? 405 ASN A CG  1 
ATOM 9090 O OD1 . ASN E 4 393 ? 157.167 175.962 117.492 1.00 105.07 ? 405 ASN A OD1 1 
ATOM 9091 N ND2 . ASN E 4 393 ? 156.102 174.285 118.523 1.00 105.07 ? 405 ASN A ND2 1 
ATOM 9092 N N   . ASN E 4 394 ? 159.814 175.942 115.088 1.00 98.98  ? 406 ASN A N   1 
ATOM 9093 C CA  . ASN E 4 394 ? 160.157 177.337 114.849 1.00 98.98  ? 406 ASN A CA  1 
ATOM 9094 C C   . ASN E 4 394 ? 159.867 177.767 113.419 1.00 98.98  ? 406 ASN A C   1 
ATOM 9095 O O   . ASN E 4 394 ? 159.272 177.015 112.641 1.00 98.98  ? 406 ASN A O   1 
ATOM 9096 C CB  . ASN E 4 394 ? 161.633 177.573 115.155 1.00 98.98  ? 406 ASN A CB  1 
ATOM 9097 C CG  . ASN E 4 394 ? 162.540 176.641 114.380 1.00 98.98  ? 406 ASN A CG  1 
ATOM 9098 O OD1 . ASN E 4 394 ? 162.565 175.436 114.625 1.00 98.98  ? 406 ASN A OD1 1 
ATOM 9099 N ND2 . ASN E 4 394 ? 163.290 177.195 113.436 1.00 98.98  ? 406 ASN A ND2 1 
ATOM 9100 N N   . ALA E 4 395 ? 160.294 178.979 113.066 1.00 98.77  ? 407 ALA A N   1 
ATOM 9101 C CA  . ALA E 4 395 ? 160.150 179.477 111.705 1.00 98.77  ? 407 ALA A CA  1 
ATOM 9102 C C   . ALA E 4 395 ? 161.116 178.746 110.782 1.00 98.77  ? 407 ALA A C   1 
ATOM 9103 O O   . ALA E 4 395 ? 161.796 177.808 111.213 1.00 98.77  ? 407 ALA A O   1 
ATOM 9104 C CB  . ALA E 4 395 ? 160.389 180.986 111.650 1.00 98.77  ? 407 ALA A CB  1 
ATOM 9105 N N   . VAL E 4 396 ? 161.171 179.154 109.513 1.00 100.95 ? 408 VAL A N   1 
ATOM 9106 C CA  . VAL E 4 396 ? 161.971 178.488 108.486 1.00 100.95 ? 408 VAL A CA  1 
ATOM 9107 C C   . VAL E 4 396 ? 161.485 177.054 108.309 1.00 100.95 ? 408 VAL A C   1 
ATOM 9108 O O   . VAL E 4 396 ? 161.128 176.643 107.200 1.00 100.95 ? 408 VAL A O   1 
ATOM 9109 C CB  . VAL E 4 396 ? 163.476 178.536 108.815 1.00 100.95 ? 408 VAL A CB  1 
ATOM 9110 C CG1 . VAL E 4 396 ? 164.215 177.398 108.128 1.00 100.95 ? 408 VAL A CG1 1 
ATOM 9111 C CG2 . VAL E 4 396 ? 164.063 179.875 108.408 1.00 100.95 ? 408 VAL A CG2 1 
ATOM 9112 N N   . THR E 4 397 ? 161.472 176.280 109.398 1.00 99.72  ? 409 THR A N   1 
ATOM 9113 C CA  . THR E 4 397 ? 160.908 174.937 109.359 1.00 99.72  ? 409 THR A CA  1 
ATOM 9114 C C   . THR E 4 397 ? 159.431 174.977 108.987 1.00 99.72  ? 409 THR A C   1 
ATOM 9115 O O   . THR E 4 397 ? 158.948 174.139 108.221 1.00 99.72  ? 409 THR A O   1 
ATOM 9116 C CB  . THR E 4 397 ? 161.100 174.246 110.711 1.00 99.72  ? 409 THR A CB  1 
ATOM 9117 O OG1 . THR E 4 397 ? 160.184 174.799 111.664 1.00 99.72  ? 409 THR A OG1 1 
ATOM 9118 C CG2 . THR E 4 397 ? 162.522 174.445 111.210 1.00 99.72  ? 409 THR A CG2 1 
ATOM 9119 N N   . LYS E 4 398 ? 158.694 175.940 109.542 1.00 104.35 ? 410 LYS A N   1 
ATOM 9120 C CA  . LYS E 4 398 ? 157.285 176.099 109.196 1.00 104.35 ? 410 LYS A CA  1 
ATOM 9121 C C   . LYS E 4 398 ? 157.117 176.523 107.740 1.00 104.35 ? 410 LYS A C   1 
ATOM 9122 O O   . LYS E 4 398 ? 156.239 176.022 107.028 1.00 104.35 ? 410 LYS A O   1 
ATOM 9123 C CB  . LYS E 4 398 ? 156.630 177.118 110.129 1.00 104.35 ? 410 LYS A CB  1 
ATOM 9124 C CG  . LYS E 4 398 ? 155.223 177.514 109.715 1.00 104.35 ? 410 LYS A CG  1 
ATOM 9125 C CD  . LYS E 4 398 ? 154.953 178.979 110.013 1.00 104.35 ? 410 LYS A CD  1 
ATOM 9126 C CE  . LYS E 4 398 ? 155.668 179.883 109.022 1.00 104.35 ? 410 LYS A CE  1 
ATOM 9127 N NZ  . LYS E 4 398 ? 155.329 179.541 107.613 1.00 104.35 ? 410 LYS A NZ  1 
ATOM 9128 N N   . MET E 4 399 ? 157.953 177.458 107.288 1.00 109.50 ? 411 MET A N   1 
ATOM 9129 C CA  . MET E 4 399 ? 157.847 178.022 105.947 1.00 109.50 ? 411 MET A CA  1 
ATOM 9130 C C   . MET E 4 399 ? 157.989 176.939 104.885 1.00 109.50 ? 411 MET A C   1 
ATOM 9131 O O   . MET E 4 399 ? 157.143 176.822 103.992 1.00 109.50 ? 411 MET A O   1 
ATOM 9132 C CB  . MET E 4 399 ? 158.898 179.115 105.757 1.00 109.50 ? 411 MET A CB  1 
ATOM 9133 C CG  . MET E 4 399 ? 159.191 179.464 104.317 1.00 109.50 ? 411 MET A CG  1 
ATOM 9134 S SD  . MET E 4 399 ? 160.845 180.149 104.146 1.00 109.50 ? 411 MET A SD  1 
ATOM 9135 C CE  . MET E 4 399 ? 160.709 181.627 105.149 1.00 109.50 ? 411 MET A CE  1 
ATOM 9136 N N   . ALA E 4 400 ? 159.054 176.143 104.968 1.00 102.53 ? 412 ALA A N   1 
ATOM 9137 C CA  . ALA E 4 400 ? 159.143 174.894 104.216 1.00 102.53 ? 412 ALA A CA  1 
ATOM 9138 C C   . ALA E 4 400 ? 158.737 173.740 105.134 1.00 102.53 ? 412 ALA A C   1 
ATOM 9139 O O   . ALA E 4 400 ? 159.564 173.084 105.764 1.00 102.53 ? 412 ALA A O   1 
ATOM 9140 C CB  . ALA E 4 400 ? 160.545 174.702 103.654 1.00 102.53 ? 412 ALA A CB  1 
ATOM 9141 N N   . GLN E 4 401 ? 157.424 173.499 105.186 1.00 102.59 ? 413 GLN A N   1 
ATOM 9142 C CA  . GLN E 4 401 ? 156.821 172.807 106.320 1.00 102.59 ? 413 GLN A CA  1 
ATOM 9143 C C   . GLN E 4 401 ? 157.432 171.433 106.559 1.00 102.59 ? 413 GLN A C   1 
ATOM 9144 O O   . GLN E 4 401 ? 157.183 170.480 105.814 1.00 102.59 ? 413 GLN A O   1 
ATOM 9145 C CB  . GLN E 4 401 ? 155.305 172.688 106.123 1.00 102.59 ? 413 GLN A CB  1 
ATOM 9146 C CG  . GLN E 4 401 ? 154.866 172.196 104.747 1.00 102.59 ? 413 GLN A CG  1 
ATOM 9147 C CD  . GLN E 4 401 ? 154.776 173.311 103.723 1.00 102.59 ? 413 GLN A CD  1 
ATOM 9148 O OE1 . GLN E 4 401 ? 155.790 173.868 103.305 1.00 102.59 ? 413 GLN A OE1 1 
ATOM 9149 N NE2 . GLN E 4 401 ? 153.557 173.640 103.313 1.00 102.59 ? 413 GLN A NE2 1 
ATOM 9150 N N   . SER E 4 402 ? 158.241 171.342 107.613 1.00 99.10  ? 414 SER A N   1 
ATOM 9151 C CA  . SER E 4 402 ? 158.802 170.088 108.094 1.00 99.10  ? 414 SER A CA  1 
ATOM 9152 C C   . SER E 4 402 ? 159.386 170.297 109.485 1.00 99.10  ? 414 SER A C   1 
ATOM 9153 O O   . SER E 4 402 ? 160.338 171.066 109.648 1.00 99.10  ? 414 SER A O   1 
ATOM 9154 C CB  . SER E 4 402 ? 159.874 169.565 107.136 1.00 99.10  ? 414 SER A CB  1 
ATOM 9155 O OG  . SER E 4 402 ? 160.795 168.728 107.814 1.00 99.10  ? 414 SER A OG  1 
ATOM 9156 N N   . SER E 4 403 ? 158.831 169.631 110.495 1.00 99.46  ? 415 SER A N   1 
ATOM 9157 C CA  . SER E 4 403 ? 159.457 169.648 111.810 1.00 99.46  ? 415 SER A CA  1 
ATOM 9158 C C   . SER E 4 403 ? 160.793 168.923 111.724 1.00 99.46  ? 415 SER A C   1 
ATOM 9159 O O   . SER E 4 403 ? 161.719 169.203 112.492 1.00 99.46  ? 415 SER A O   1 
ATOM 9160 C CB  . SER E 4 403 ? 158.550 169.001 112.859 1.00 99.46  ? 415 SER A CB  1 
ATOM 9161 O OG  . SER E 4 403 ? 159.274 168.699 114.039 1.00 99.46  ? 415 SER A OG  1 
ATOM 9162 N N   . SER E 4 404 ? 160.887 167.986 110.783 1.00 103.89 ? 416 SER A N   1 
ATOM 9163 C CA  . SER E 4 404 ? 162.086 167.189 110.562 1.00 103.89 ? 416 SER A CA  1 
ATOM 9164 C C   . SER E 4 404 ? 163.183 167.994 109.874 1.00 103.89 ? 416 SER A C   1 
ATOM 9165 O O   . SER E 4 404 ? 164.333 167.548 109.801 1.00 103.89 ? 416 SER A O   1 
ATOM 9166 C CB  . SER E 4 404 ? 161.737 165.954 109.732 1.00 103.89 ? 416 SER A CB  1 
ATOM 9167 O OG  . SER E 4 404 ? 161.306 164.890 110.562 1.00 103.89 ? 416 SER A OG  1 
ATOM 9168 N N   . LYS E 4 405 ? 162.837 169.170 109.350 1.00 96.14  ? 417 LYS A N   1 
ATOM 9169 C CA  . LYS E 4 405 ? 163.786 169.991 108.605 1.00 96.14  ? 417 LYS A CA  1 
ATOM 9170 C C   . LYS E 4 405 ? 164.914 170.510 109.488 1.00 96.14  ? 417 LYS A C   1 
ATOM 9171 O O   . LYS E 4 405 ? 166.061 170.609 109.040 1.00 96.14  ? 417 LYS A O   1 
ATOM 9172 C CB  . LYS E 4 405 ? 163.067 171.166 107.939 1.00 96.14  ? 417 LYS A CB  1 
ATOM 9173 C CG  . LYS E 4 405 ? 163.967 172.050 107.087 1.00 96.14  ? 417 LYS A CG  1 
ATOM 9174 C CD  . LYS E 4 405 ? 164.803 171.231 106.117 1.00 96.14  ? 417 LYS A CD  1 
ATOM 9175 C CE  . LYS E 4 405 ? 165.432 172.111 105.049 1.00 96.14  ? 417 LYS A CE  1 
ATOM 9176 N NZ  . LYS E 4 405 ? 164.412 172.885 104.291 1.00 96.14  ? 417 LYS A NZ  1 
ATOM 9177 N N   . SER E 4 406 ? 164.600 170.846 110.737 1.00 97.74  ? 418 SER A N   1 
ATOM 9178 C CA  . SER E 4 406 ? 165.567 171.469 111.635 1.00 97.74  ? 418 SER A CA  1 
ATOM 9179 C C   . SER E 4 406 ? 166.814 170.606 111.829 1.00 97.74  ? 418 SER A C   1 
ATOM 9180 O O   . SER E 4 406 ? 167.929 171.142 111.784 1.00 97.74  ? 418 SER A O   1 
ATOM 9181 C CB  . SER E 4 406 ? 164.916 171.795 112.983 1.00 97.74  ? 418 SER A CB  1 
ATOM 9182 O OG  . SER E 4 406 ? 165.536 172.912 113.594 1.00 97.74  ? 418 SER A OG  1 
ATOM 9183 N N   . PRO E 4 407 ? 166.694 169.279 112.059 1.00 100.96 ? 419 PRO A N   1 
ATOM 9184 C CA  . PRO E 4 407 ? 167.908 168.451 112.111 1.00 100.96 ? 419 PRO A CA  1 
ATOM 9185 C C   . PRO E 4 407 ? 168.727 168.508 110.830 1.00 100.96 ? 419 PRO A C   1 
ATOM 9186 O O   . PRO E 4 407 ? 169.961 168.489 110.880 1.00 100.96 ? 419 PRO A O   1 
ATOM 9187 C CB  . PRO E 4 407 ? 167.369 167.036 112.349 1.00 100.96 ? 419 PRO A CB  1 
ATOM 9188 C CG  . PRO E 4 407 ? 166.048 167.211 112.954 1.00 100.96 ? 419 PRO A CG  1 
ATOM 9189 C CD  . PRO E 4 407 ? 165.511 168.547 112.552 1.00 100.96 ? 419 PRO A CD  1 
ATOM 9190 N N   . GLU E 4 408 ? 168.052 168.581 109.681 1.00 96.82  ? 420 GLU A N   1 
ATOM 9191 C CA  . GLU E 4 408 ? 168.745 168.512 108.397 1.00 96.82  ? 420 GLU A CA  1 
ATOM 9192 C C   . GLU E 4 408 ? 169.718 169.671 108.225 1.00 96.82  ? 420 GLU A C   1 
ATOM 9193 O O   . GLU E 4 408 ? 170.859 169.485 107.788 1.00 96.82  ? 420 GLU A O   1 
ATOM 9194 C CB  . GLU E 4 408 ? 167.730 168.494 107.254 1.00 96.82  ? 420 GLU A CB  1 
ATOM 9195 C CG  . GLU E 4 408 ? 168.365 168.368 105.882 1.00 96.82  ? 420 GLU A CG  1 
ATOM 9196 C CD  . GLU E 4 408 ? 167.490 168.928 104.780 1.00 96.82  ? 420 GLU A CD  1 
ATOM 9197 O OE1 . GLU E 4 408 ? 166.287 168.595 104.749 1.00 96.82  ? 420 GLU A OE1 1 
ATOM 9198 O OE2 . GLU E 4 408 ? 168.005 169.700 103.945 1.00 96.82  ? 420 GLU A OE2 1 
ATOM 9199 N N   . LEU E 4 409 ? 169.277 170.883 108.561 1.00 93.71  ? 421 LEU A N   1 
ATOM 9200 C CA  . LEU E 4 409 ? 170.149 172.046 108.452 1.00 93.71  ? 421 LEU A CA  1 
ATOM 9201 C C   . LEU E 4 409 ? 171.341 171.911 109.391 1.00 93.71  ? 421 LEU A C   1 
ATOM 9202 O O   . LEU E 4 409 ? 172.475 172.248 109.037 1.00 93.71  ? 421 LEU A O   1 
ATOM 9203 C CB  . LEU E 4 409 ? 169.354 173.318 108.745 1.00 93.71  ? 421 LEU A CB  1 
ATOM 9204 C CG  . LEU E 4 409 ? 168.352 173.701 107.655 1.00 93.71  ? 421 LEU A CG  1 
ATOM 9205 C CD1 . LEU E 4 409 ? 166.986 173.996 108.253 1.00 93.71  ? 421 LEU A CD1 1 
ATOM 9206 C CD2 . LEU E 4 409 ? 168.861 174.886 106.853 1.00 93.71  ? 421 LEU A CD2 1 
ATOM 9207 N N   . LEU E 4 410 ? 171.093 171.413 110.601 1.00 95.63  ? 422 LEU A N   1 
ATOM 9208 C CA  . LEU E 4 410 ? 172.169 171.063 111.518 1.00 95.63  ? 422 LEU A CA  1 
ATOM 9209 C C   . LEU E 4 410 ? 173.025 169.954 110.925 1.00 95.63  ? 422 LEU A C   1 
ATOM 9210 O O   . LEU E 4 410 ? 174.257 170.009 110.991 1.00 95.63  ? 422 LEU A O   1 
ATOM 9211 C CB  . LEU E 4 410 ? 171.610 170.622 112.869 1.00 95.63  ? 422 LEU A CB  1 
ATOM 9212 C CG  . LEU E 4 410 ? 172.645 170.335 113.959 1.00 95.63  ? 422 LEU A CG  1 
ATOM 9213 C CD1 . LEU E 4 410 ? 173.771 171.357 113.948 1.00 95.63  ? 422 LEU A CD1 1 
ATOM 9214 C CD2 . LEU E 4 410 ? 171.988 170.267 115.319 1.00 95.63  ? 422 LEU A CD2 1 
ATOM 9215 N N   . ALA E 4 411 ? 172.375 168.942 110.347 1.00 96.01  ? 423 ALA A N   1 
ATOM 9216 C CA  . ALA E 4 411 ? 173.102 167.809 109.786 1.00 96.01  ? 423 ALA A CA  1 
ATOM 9217 C C   . ALA E 4 411 ? 174.047 168.264 108.684 1.00 96.01  ? 423 ALA A C   1 
ATOM 9218 O O   . ALA E 4 411 ? 175.200 167.824 108.611 1.00 96.01  ? 423 ALA A O   1 
ATOM 9219 C CB  . ALA E 4 411 ? 172.119 166.763 109.259 1.00 96.01  ? 423 ALA A CB  1 
ATOM 9220 N N   . ARG E 4 412 ? 173.571 169.154 107.814 1.00 95.17  ? 424 ARG A N   1 
ATOM 9221 C CA  . ARG E 4 412 ? 174.435 169.678 106.767 1.00 95.17  ? 424 ARG A CA  1 
ATOM 9222 C C   . ARG E 4 412 ? 175.554 170.533 107.344 1.00 95.17  ? 424 ARG A C   1 
ATOM 9223 O O   . ARG E 4 412 ? 176.671 170.520 106.820 1.00 95.17  ? 424 ARG A O   1 
ATOM 9224 C CB  . ARG E 4 412 ? 173.610 170.474 105.755 1.00 95.17  ? 424 ARG A CB  1 
ATOM 9225 C CG  . ARG E 4 412 ? 174.368 170.856 104.494 1.00 95.17  ? 424 ARG A CG  1 
ATOM 9226 C CD  . ARG E 4 412 ? 173.547 171.773 103.598 1.00 95.17  ? 424 ARG A CD  1 
ATOM 9227 N NE  . ARG E 4 412 ? 172.590 171.037 102.780 1.00 95.17  ? 424 ARG A NE  1 
ATOM 9228 C CZ  . ARG E 4 412 ? 171.341 170.768 103.137 1.00 95.17  ? 424 ARG A CZ  1 
ATOM 9229 N NH1 . ARG E 4 412 ? 170.851 171.171 104.297 1.00 95.17  ? 424 ARG A NH1 1 
ATOM 9230 N NH2 . ARG E 4 412 ? 170.564 170.078 102.307 1.00 95.17  ? 424 ARG A NH2 1 
ATOM 9231 N N   . TYR E 4 413 ? 175.285 171.269 108.428 1.00 97.49  ? 425 TYR A N   1 
ATOM 9232 C CA  . TYR E 4 413 ? 176.293 172.180 108.968 1.00 97.49  ? 425 TYR A CA  1 
ATOM 9233 C C   . TYR E 4 413 ? 177.537 171.444 109.443 1.00 97.49  ? 425 TYR A C   1 
ATOM 9234 O O   . TYR E 4 413 ? 178.657 171.812 109.071 1.00 97.49  ? 425 TYR A O   1 
ATOM 9235 C CB  . TYR E 4 413 ? 175.726 172.989 110.128 1.00 97.49  ? 425 TYR A CB  1 
ATOM 9236 C CG  . TYR E 4 413 ? 176.776 173.862 110.782 1.00 97.49  ? 425 TYR A CG  1 
ATOM 9237 C CD1 . TYR E 4 413 ? 177.480 174.806 110.047 1.00 97.49  ? 425 TYR A CD1 1 
ATOM 9238 C CD2 . TYR E 4 413 ? 177.097 173.708 112.124 1.00 97.49  ? 425 TYR A CD2 1 
ATOM 9239 C CE1 . TYR E 4 413 ? 178.449 175.595 110.639 1.00 97.49  ? 425 TYR A CE1 1 
ATOM 9240 C CE2 . TYR E 4 413 ? 178.063 174.489 112.722 1.00 97.49  ? 425 TYR A CE2 1 
ATOM 9241 C CZ  . TYR E 4 413 ? 178.735 175.431 111.977 1.00 97.49  ? 425 TYR A CZ  1 
ATOM 9242 O OH  . TYR E 4 413 ? 179.699 176.207 112.579 1.00 97.49  ? 425 TYR A OH  1 
ATOM 9243 N N   . CYS E 4 414 ? 177.366 170.417 110.279 1.00 108.57 ? 426 CYS A N   1 
ATOM 9244 C CA  . CYS E 4 414 ? 178.521 169.708 110.819 1.00 108.57 ? 426 CYS A CA  1 
ATOM 9245 C C   . CYS E 4 414 ? 179.313 169.047 109.703 1.00 108.57 ? 426 CYS A C   1 
ATOM 9246 O O   . CYS E 4 414 ? 180.550 169.058 109.709 1.00 108.57 ? 426 CYS A O   1 
ATOM 9247 C CB  . CYS E 4 414 ? 178.073 168.676 111.856 1.00 108.57 ? 426 CYS A CB  1 
ATOM 9248 S SG  . CYS E 4 414 ? 176.489 167.879 111.529 1.00 108.57 ? 426 CYS A SG  1 
ATOM 9249 N N   . ASP E 4 415 ? 178.608 168.467 108.732 1.00 110.60 ? 427 ASP A N   1 
ATOM 9250 C CA  . ASP E 4 415 ? 179.260 167.890 107.563 1.00 110.60 ? 427 ASP A CA  1 
ATOM 9251 C C   . ASP E 4 415 ? 179.957 168.982 106.760 1.00 110.60 ? 427 ASP A C   1 
ATOM 9252 O O   . ASP E 4 415 ? 181.068 168.792 106.253 1.00 110.60 ? 427 ASP A O   1 
ATOM 9253 C CB  . ASP E 4 415 ? 178.210 167.147 106.726 1.00 110.60 ? 427 ASP A CB  1 
ATOM 9254 C CG  . ASP E 4 415 ? 178.731 166.654 105.382 1.00 110.60 ? 427 ASP A CG  1 
ATOM 9255 O OD1 . ASP E 4 415 ? 179.951 166.690 105.114 1.00 110.60 ? 427 ASP A OD1 1 
ATOM 9256 O OD2 . ASP E 4 415 ? 177.892 166.217 104.567 1.00 110.60 ? 427 ASP A OD2 1 
ATOM 9257 N N   . SER E 4 416 ? 179.323 170.152 106.665 1.00 105.66 ? 428 SER A N   1 
ATOM 9258 C CA  . SER E 4 416 ? 179.847 171.266 105.882 1.00 105.66 ? 428 SER A CA  1 
ATOM 9259 C C   . SER E 4 416 ? 181.246 171.649 106.343 1.00 105.66 ? 428 SER A C   1 
ATOM 9260 O O   . SER E 4 416 ? 182.126 171.911 105.518 1.00 105.66 ? 428 SER A O   1 
ATOM 9261 C CB  . SER E 4 416 ? 178.918 172.480 105.973 1.00 105.66 ? 428 SER A CB  1 
ATOM 9262 O OG  . SER E 4 416 ? 177.622 172.171 105.492 1.00 105.66 ? 428 SER A OG  1 
ATOM 9263 N N   . LEU E 4 417 ? 181.469 171.674 107.655 1.00 105.67 ? 429 LEU A N   1 
ATOM 9264 C CA  . LEU E 4 417 ? 182.787 171.983 108.193 1.00 105.67 ? 429 LEU A CA  1 
ATOM 9265 C C   . LEU E 4 417 ? 183.679 170.749 108.257 1.00 105.67 ? 429 LEU A C   1 
ATOM 9266 O O   . LEU E 4 417 ? 184.891 170.845 108.044 1.00 105.67 ? 429 LEU A O   1 
ATOM 9267 C CB  . LEU E 4 417 ? 182.644 172.627 109.580 1.00 105.67 ? 429 LEU A CB  1 
ATOM 9268 C CG  . LEU E 4 417 ? 183.821 172.727 110.556 1.00 105.67 ? 429 LEU A CG  1 
ATOM 9269 C CD1 . LEU E 4 417 ? 183.587 173.899 111.493 1.00 105.67 ? 429 LEU A CD1 1 
ATOM 9270 C CD2 . LEU E 4 417 ? 184.004 171.451 111.362 1.00 105.67 ? 429 LEU A CD2 1 
ATOM 9271 N N   . LEU E 4 418 ? 183.098 169.585 108.551 1.00 109.63 ? 430 LEU A N   1 
ATOM 9272 C CA  . LEU E 4 418 ? 183.846 168.329 108.600 1.00 109.63 ? 430 LEU A CA  1 
ATOM 9273 C C   . LEU E 4 418 ? 183.862 167.695 107.203 1.00 109.63 ? 430 LEU A C   1 
ATOM 9274 O O   . LEU E 4 418 ? 183.241 166.676 106.915 1.00 109.63 ? 430 LEU A O   1 
ATOM 9275 C CB  . LEU E 4 418 ? 183.262 167.429 109.690 1.00 109.63 ? 430 LEU A CB  1 
ATOM 9276 C CG  . LEU E 4 418 ? 183.425 165.926 109.955 1.00 109.63 ? 430 LEU A CG  1 
ATOM 9277 C CD1 . LEU E 4 418 ? 183.182 165.690 111.431 1.00 109.63 ? 430 LEU A CD1 1 
ATOM 9278 C CD2 . LEU E 4 418 ? 182.427 165.077 109.191 1.00 109.63 ? 430 LEU A CD2 1 
ATOM 9279 N N   . LYS E 4 419 ? 184.569 168.374 106.303 1.00 110.83 ? 431 LYS A N   1 
ATOM 9280 C CA  . LYS E 4 419 ? 184.736 167.925 104.926 1.00 110.83 ? 431 LYS A CA  1 
ATOM 9281 C C   . LYS E 4 419 ? 186.137 168.295 104.472 1.00 110.83 ? 431 LYS A C   1 
ATOM 9282 O O   . LYS E 4 419 ? 186.762 169.185 105.056 1.00 110.83 ? 431 LYS A O   1 
ATOM 9283 C CB  . LYS E 4 419 ? 183.699 168.560 103.995 1.00 110.83 ? 431 LYS A CB  1 
ATOM 9284 C CG  . LYS E 4 419 ? 182.632 167.611 103.475 1.00 110.83 ? 431 LYS A CG  1 
ATOM 9285 C CD  . LYS E 4 419 ? 181.851 168.252 102.334 1.00 110.83 ? 431 LYS A CD  1 
ATOM 9286 C CE  . LYS E 4 419 ? 180.956 169.382 102.814 1.00 110.83 ? 431 LYS A CE  1 
ATOM 9287 N NZ  . LYS E 4 419 ? 179.808 168.874 103.606 1.00 110.83 ? 431 LYS A NZ  1 
ATOM 9288 N N   . LYS E 4 420 ? 186.631 167.615 103.439 1.00 120.24 ? 432 LYS A N   1 
ATOM 9289 C CA  . LYS E 4 420 ? 187.846 168.070 102.780 1.00 120.24 ? 432 LYS A CA  1 
ATOM 9290 C C   . LYS E 4 420 ? 187.544 169.366 102.041 1.00 120.24 ? 432 LYS A C   1 
ATOM 9291 O O   . LYS E 4 420 ? 186.637 169.414 101.204 1.00 120.24 ? 432 LYS A O   1 
ATOM 9292 C CB  . LYS E 4 420 ? 188.385 167.009 101.818 1.00 120.24 ? 432 LYS A CB  1 
ATOM 9293 C CG  . LYS E 4 420 ? 189.739 167.343 101.207 1.00 120.24 ? 432 LYS A CG  1 
ATOM 9294 C CD  . LYS E 4 420 ? 190.827 167.492 102.263 1.00 120.24 ? 432 LYS A CD  1 
ATOM 9295 C CE  . LYS E 4 420 ? 190.890 166.282 103.185 1.00 120.24 ? 432 LYS A CE  1 
ATOM 9296 N NZ  . LYS E 4 420 ? 192.180 166.215 103.925 1.00 120.24 ? 432 LYS A NZ  1 
ATOM 9297 N N   . SER E 4 421 ? 188.295 170.417 102.341 1.00 125.76 ? 433 SER A N   1 
ATOM 9298 C CA  . SER E 4 421 ? 188.028 171.745 101.802 1.00 125.76 ? 433 SER A CA  1 
ATOM 9299 C C   . SER E 4 421 ? 189.370 172.380 101.458 1.00 125.76 ? 433 SER A C   1 
ATOM 9300 O O   . SER E 4 421 ? 190.387 171.690 101.324 1.00 125.76 ? 433 SER A O   1 
ATOM 9301 C CB  . SER E 4 421 ? 187.204 172.574 102.798 1.00 125.76 ? 433 SER A CB  1 
ATOM 9302 O OG  . SER E 4 421 ? 187.590 172.295 104.132 1.00 125.76 ? 433 SER A OG  1 
ATOM 9303 N N   . SER E 4 422 ? 189.367 173.702 101.276 1.00 128.77 ? 434 SER A N   1 
ATOM 9304 C CA  . SER E 4 422 ? 190.586 174.467 101.037 1.00 128.77 ? 434 SER A CA  1 
ATOM 9305 C C   . SER E 4 422 ? 191.682 174.060 102.015 1.00 128.77 ? 434 SER A C   1 
ATOM 9306 O O   . SER E 4 422 ? 192.753 173.607 101.599 1.00 128.77 ? 434 SER A O   1 
ATOM 9307 C CB  . SER E 4 422 ? 190.305 175.966 101.149 1.00 128.77 ? 434 SER A CB  1 
ATOM 9308 O OG  . SER E 4 422 ? 190.510 176.425 102.474 1.00 128.77 ? 434 SER A OG  1 
ATOM 9309 N N   . LYS E 4 423 ? 191.413 174.209 103.312 1.00 128.05 ? 435 LYS A N   1 
ATOM 9310 C CA  . LYS E 4 423 ? 192.323 173.744 104.352 1.00 128.05 ? 435 LYS A CA  1 
ATOM 9311 C C   . LYS E 4 423 ? 191.643 173.777 105.715 1.00 128.05 ? 435 LYS A C   1 
ATOM 9312 O O   . LYS E 4 423 ? 190.995 174.768 106.064 1.00 128.05 ? 435 LYS A O   1 
ATOM 9313 C CB  . LYS E 4 423 ? 193.597 174.595 104.382 1.00 128.05 ? 435 LYS A CB  1 
ATOM 9314 C CG  . LYS E 4 423 ? 194.277 174.649 105.741 1.00 128.05 ? 435 LYS A CG  1 
ATOM 9315 C CD  . LYS E 4 423 ? 195.745 175.017 105.610 1.00 128.05 ? 435 LYS A CD  1 
ATOM 9316 C CE  . LYS E 4 423 ? 196.456 174.927 106.949 1.00 128.05 ? 435 LYS A CE  1 
ATOM 9317 N NZ  . LYS E 4 423 ? 196.440 173.540 107.490 1.00 128.05 ? 435 LYS A NZ  1 
ATOM 9318 N N   . ASN E 4 424 ? 191.771 172.701 106.482 1.00 129.09 ? 436 ASN A N   1 
ATOM 9319 C CA  . ASN E 4 424 ? 191.359 172.741 107.876 1.00 129.09 ? 436 ASN A CA  1 
ATOM 9320 C C   . ASN E 4 424 ? 192.293 173.681 108.633 1.00 129.09 ? 436 ASN A C   1 
ATOM 9321 O O   . ASN E 4 424 ? 193.451 173.323 108.888 1.00 129.09 ? 436 ASN A O   1 
ATOM 9322 C CB  . ASN E 4 424 ? 191.392 171.342 108.490 1.00 129.09 ? 436 ASN A CB  1 
ATOM 9323 C CG  . ASN E 4 424 ? 191.343 171.369 110.003 1.00 129.09 ? 436 ASN A CG  1 
ATOM 9324 O OD1 . ASN E 4 424 ? 190.449 171.972 110.596 1.00 129.09 ? 436 ASN A OD1 1 
ATOM 9325 N ND2 . ASN E 4 424 ? 192.311 170.718 110.638 1.00 129.09 ? 436 ASN A ND2 1 
ATOM 9326 N N   . PRO E 4 425 ? 191.840 174.878 109.005 1.00 130.71 ? 437 PRO A N   1 
ATOM 9327 C CA  . PRO E 4 425 ? 192.783 175.912 109.454 1.00 130.71 ? 437 PRO A CA  1 
ATOM 9328 C C   . PRO E 4 425 ? 193.333 175.689 110.855 1.00 130.71 ? 437 PRO A C   1 
ATOM 9329 O O   . PRO E 4 425 ? 194.529 175.886 111.090 1.00 130.71 ? 437 PRO A O   1 
ATOM 9330 C CB  . PRO E 4 425 ? 191.953 177.201 109.378 1.00 130.71 ? 437 PRO A CB  1 
ATOM 9331 C CG  . PRO E 4 425 ? 190.507 176.769 109.285 1.00 130.71 ? 437 PRO A CG  1 
ATOM 9332 C CD  . PRO E 4 425 ? 190.438 175.273 109.209 1.00 130.71 ? 437 PRO A CD  1 
ATOM 9333 N N   . GLU E 4 426 ? 192.481 175.291 111.793 1.00 131.28 ? 438 GLU A N   1 
ATOM 9334 C CA  . GLU E 4 426 ? 192.881 175.109 113.182 1.00 131.28 ? 438 GLU A CA  1 
ATOM 9335 C C   . GLU E 4 426 ? 192.390 173.757 113.684 1.00 131.28 ? 438 GLU A C   1 
ATOM 9336 O O   . GLU E 4 426 ? 191.272 173.337 113.364 1.00 131.28 ? 438 GLU A O   1 
ATOM 9337 C CB  . GLU E 4 426 ? 192.339 176.237 114.062 1.00 131.28 ? 438 GLU A CB  1 
ATOM 9338 C CG  . GLU E 4 426 ? 192.621 177.646 113.543 1.00 131.28 ? 438 GLU A CG  1 
ATOM 9339 C CD  . GLU E 4 426 ? 193.797 178.312 114.247 1.00 131.28 ? 438 GLU A CD  1 
ATOM 9340 O OE1 . GLU E 4 426 ? 194.077 177.957 115.411 1.00 131.28 ? 438 GLU A OE1 1 
ATOM 9341 O OE2 . GLU E 4 426 ? 194.442 179.191 113.636 1.00 131.28 ? 438 GLU A OE2 1 
ATOM 9342 N N   . GLU E 4 427 ? 193.235 173.073 114.457 1.00 132.78 ? 439 GLU A N   1 
ATOM 9343 C CA  . GLU E 4 427 ? 192.795 171.844 115.105 1.00 132.78 ? 439 GLU A CA  1 
ATOM 9344 C C   . GLU E 4 427 ? 191.816 172.152 116.233 1.00 132.78 ? 439 GLU A C   1 
ATOM 9345 O O   . GLU E 4 427 ? 190.914 171.352 116.519 1.00 132.78 ? 439 GLU A O   1 
ATOM 9346 C CB  . GLU E 4 427 ? 193.998 171.059 115.633 1.00 132.78 ? 439 GLU A CB  1 
ATOM 9347 C CG  . GLU E 4 427 ? 193.671 169.649 116.119 1.00 132.78 ? 439 GLU A CG  1 
ATOM 9348 C CD  . GLU E 4 427 ? 192.925 168.813 115.087 1.00 132.78 ? 439 GLU A CD  1 
ATOM 9349 O OE1 . GLU E 4 427 ? 192.214 167.867 115.485 1.00 132.78 ? 439 GLU A OE1 1 
ATOM 9350 O OE2 . GLU E 4 427 ? 193.081 169.069 113.873 1.00 132.78 ? 439 GLU A OE2 1 
ATOM 9351 N N   . ALA E 4 428 ? 191.984 173.305 116.889 1.00 128.68 ? 440 ALA A N   1 
ATOM 9352 C CA  . ALA E 4 428 ? 191.088 173.693 117.970 1.00 128.68 ? 440 ALA A CA  1 
ATOM 9353 C C   . ALA E 4 428 ? 189.677 173.950 117.458 1.00 128.68 ? 440 ALA A C   1 
ATOM 9354 O O   . ALA E 4 428 ? 188.704 173.476 118.050 1.00 128.68 ? 440 ALA A O   1 
ATOM 9355 C CB  . ALA E 4 428 ? 191.620 174.926 118.695 1.00 128.68 ? 440 ALA A CB  1 
ATOM 9356 N N   . GLU E 4 429 ? 189.553 174.695 116.360 1.00 128.14 ? 441 GLU A N   1 
ATOM 9357 C CA  . GLU E 4 429 ? 188.239 175.027 115.820 1.00 128.14 ? 441 GLU A CA  1 
ATOM 9358 C C   . GLU E 4 429 ? 187.506 173.754 115.418 1.00 128.14 ? 441 GLU A C   1 
ATOM 9359 O O   . GLU E 4 429 ? 186.272 173.714 115.399 1.00 128.14 ? 441 GLU A O   1 
ATOM 9360 C CB  . GLU E 4 429 ? 188.370 176.011 114.647 1.00 128.14 ? 441 GLU A CB  1 
ATOM 9361 C CG  . GLU E 4 429 ? 188.861 175.431 113.324 1.00 128.14 ? 441 GLU A CG  1 
ATOM 9362 C CD  . GLU E 4 429 ? 187.770 174.755 112.515 1.00 128.14 ? 441 GLU A CD  1 
ATOM 9363 O OE1 . GLU E 4 429 ? 186.577 174.943 112.837 1.00 128.14 ? 441 GLU A OE1 1 
ATOM 9364 O OE2 . GLU E 4 429 ? 188.108 174.039 111.550 1.00 128.14 ? 441 GLU A OE2 1 
ATOM 9365 N N   . LEU E 4 430 ? 188.264 172.709 115.100 1.00 126.66 ? 442 LEU A N   1 
ATOM 9366 C CA  . LEU E 4 430 ? 187.687 171.422 114.743 1.00 126.66 ? 442 LEU A CA  1 
ATOM 9367 C C   . LEU E 4 430 ? 186.977 170.784 115.934 1.00 126.66 ? 442 LEU A C   1 
ATOM 9368 O O   . LEU E 4 430 ? 185.985 170.075 115.757 1.00 126.66 ? 442 LEU A O   1 
ATOM 9369 C CB  . LEU E 4 430 ? 188.771 170.492 114.203 1.00 126.66 ? 442 LEU A CB  1 
ATOM 9370 C CG  . LEU E 4 430 ? 188.265 169.298 113.403 1.00 126.66 ? 442 LEU A CG  1 
ATOM 9371 C CD1 . LEU E 4 430 ? 187.135 169.725 112.475 1.00 126.66 ? 442 LEU A CD1 1 
ATOM 9372 C CD2 . LEU E 4 430 ? 189.410 168.690 112.621 1.00 126.66 ? 442 LEU A CD2 1 
ATOM 9373 N N   . GLU E 4 431 ? 187.487 170.998 117.149 1.00 126.45 ? 443 GLU A N   1 
ATOM 9374 C CA  . GLU E 4 431 ? 186.797 170.491 118.332 1.00 126.45 ? 443 GLU A CA  1 
ATOM 9375 C C   . GLU E 4 431 ? 185.651 171.399 118.759 1.00 126.45 ? 443 GLU A C   1 
ATOM 9376 O O   . GLU E 4 431 ? 184.509 170.948 118.908 1.00 126.45 ? 443 GLU A O   1 
ATOM 9377 C CB  . GLU E 4 431 ? 187.782 170.296 119.498 1.00 126.45 ? 443 GLU A CB  1 
ATOM 9378 C CG  . GLU E 4 431 ? 189.254 169.962 119.172 1.00 126.45 ? 443 GLU A CG  1 
ATOM 9379 C CD  . GLU E 4 431 ? 189.462 168.926 118.074 1.00 126.45 ? 443 GLU A CD  1 
ATOM 9380 O OE1 . GLU E 4 431 ? 190.619 168.765 117.628 1.00 126.45 ? 443 GLU A OE1 1 
ATOM 9381 O OE2 . GLU E 4 431 ? 188.508 168.210 117.693 1.00 126.45 ? 443 GLU A OE2 1 
ATOM 9382 N N   . ASP E 4 432 ? 185.935 172.687 118.952 1.00 126.32 ? 444 ASP A N   1 
ATOM 9383 C CA  . ASP E 4 432 ? 184.983 173.583 119.599 1.00 126.32 ? 444 ASP A CA  1 
ATOM 9384 C C   . ASP E 4 432 ? 183.688 173.745 118.807 1.00 126.32 ? 444 ASP A C   1 
ATOM 9385 O O   . ASP E 4 432 ? 182.602 173.736 119.395 1.00 126.32 ? 444 ASP A O   1 
ATOM 9386 C CB  . ASP E 4 432 ? 185.649 174.939 119.888 1.00 126.32 ? 444 ASP A CB  1 
ATOM 9387 C CG  . ASP E 4 432 ? 185.967 175.740 118.633 1.00 126.32 ? 444 ASP A CG  1 
ATOM 9388 O OD1 . ASP E 4 432 ? 185.537 175.359 117.528 1.00 126.32 ? 444 ASP A OD1 1 
ATOM 9389 O OD2 . ASP E 4 432 ? 186.673 176.762 118.758 1.00 126.32 ? 444 ASP A OD2 1 
ATOM 9390 N N   . THR E 4 433 ? 183.781 173.871 117.481 1.00 118.93 ? 445 THR A N   1 
ATOM 9391 C CA  . THR E 4 433 ? 182.576 173.957 116.662 1.00 118.93 ? 445 THR A CA  1 
ATOM 9392 C C   . THR E 4 433 ? 181.720 172.705 116.809 1.00 118.93 ? 445 THR A C   1 
ATOM 9393 O O   . THR E 4 433 ? 180.497 172.786 116.965 1.00 118.93 ? 445 THR A O   1 
ATOM 9394 C CB  . THR E 4 433 ? 182.949 174.186 115.195 1.00 118.93 ? 445 THR A CB  1 
ATOM 9395 O OG1 . THR E 4 433 ? 183.921 173.215 114.789 1.00 118.93 ? 445 THR A OG1 1 
ATOM 9396 C CG2 . THR E 4 433 ? 183.510 175.584 114.996 1.00 118.93 ? 445 THR A CG2 1 
ATOM 9397 N N   . LEU E 4 434 ? 182.353 171.532 116.770 1.00 117.36 ? 446 LEU A N   1 
ATOM 9398 C CA  . LEU E 4 434 ? 181.632 170.291 117.032 1.00 117.36 ? 446 LEU A CA  1 
ATOM 9399 C C   . LEU E 4 434 ? 181.108 170.260 118.463 1.00 117.36 ? 446 LEU A C   1 
ATOM 9400 O O   . LEU E 4 434 ? 179.979 169.828 118.717 1.00 117.36 ? 446 LEU A O   1 
ATOM 9401 C CB  . LEU E 4 434 ? 182.524 169.078 116.745 1.00 117.36 ? 446 LEU A CB  1 
ATOM 9402 C CG  . LEU E 4 434 ? 182.856 168.666 115.302 1.00 117.36 ? 446 LEU A CG  1 
ATOM 9403 C CD1 . LEU E 4 434 ? 181.662 167.957 114.689 1.00 117.36 ? 446 LEU A CD1 1 
ATOM 9404 C CD2 . LEU E 4 434 ? 183.265 169.820 114.408 1.00 117.36 ? 446 LEU A CD2 1 
ATOM 9405 N N   . ASN E 4 435 ? 181.921 170.726 119.414 1.00 118.87 ? 447 ASN A N   1 
ATOM 9406 C CA  . ASN E 4 435 ? 181.459 170.835 120.794 1.00 118.87 ? 447 ASN A CA  1 
ATOM 9407 C C   . ASN E 4 435 ? 180.288 171.803 120.899 1.00 118.87 ? 447 ASN A C   1 
ATOM 9408 O O   . ASN E 4 435 ? 179.320 171.551 121.623 1.00 118.87 ? 447 ASN A O   1 
ATOM 9409 C CB  . ASN E 4 435 ? 182.610 171.271 121.704 1.00 118.87 ? 447 ASN A CB  1 
ATOM 9410 C CG  . ASN E 4 435 ? 183.600 170.153 121.964 1.00 118.87 ? 447 ASN A CG  1 
ATOM 9411 O OD1 . ASN E 4 435 ? 184.784 170.269 121.648 1.00 118.87 ? 447 ASN A OD1 1 
ATOM 9412 N ND2 . ASN E 4 435 ? 183.119 169.062 122.549 1.00 118.87 ? 447 ASN A ND2 1 
ATOM 9413 N N   . GLN E 4 436 ? 180.364 172.923 120.178 1.00 118.85 ? 448 GLN A N   1 
ATOM 9414 C CA  . GLN E 4 436 ? 179.235 173.845 120.117 1.00 118.85 ? 448 GLN A CA  1 
ATOM 9415 C C   . GLN E 4 436 ? 178.034 173.185 119.450 1.00 118.85 ? 448 GLN A C   1 
ATOM 9416 O O   . GLN E 4 436 ? 176.884 173.412 119.841 1.00 118.85 ? 448 GLN A O   1 
ATOM 9417 C CB  . GLN E 4 436 ? 179.635 175.119 119.370 1.00 118.85 ? 448 GLN A CB  1 
ATOM 9418 C CG  . GLN E 4 436 ? 180.551 176.058 120.152 1.00 118.85 ? 448 GLN A CG  1 
ATOM 9419 C CD  . GLN E 4 436 ? 179.804 176.968 121.111 1.00 118.85 ? 448 GLN A CD  1 
ATOM 9420 O OE1 . GLN E 4 436 ? 178.751 176.610 121.638 1.00 118.85 ? 448 GLN A OE1 1 
ATOM 9421 N NE2 . GLN E 4 436 ? 180.351 178.156 121.341 1.00 118.85 ? 448 GLN A NE2 1 
ATOM 9422 N N   . VAL E 4 437 ? 178.289 172.366 118.425 1.00 108.32 ? 449 VAL A N   1 
ATOM 9423 C CA  . VAL E 4 437 ? 177.211 171.634 117.760 1.00 108.32 ? 449 VAL A CA  1 
ATOM 9424 C C   . VAL E 4 437 ? 176.541 170.680 118.741 1.00 108.32 ? 449 VAL A C   1 
ATOM 9425 O O   . VAL E 4 437 ? 175.317 170.502 118.729 1.00 108.32 ? 449 VAL A O   1 
ATOM 9426 C CB  . VAL E 4 437 ? 177.750 170.892 116.523 1.00 108.32 ? 449 VAL A CB  1 
ATOM 9427 C CG1 . VAL E 4 437 ? 176.871 169.699 116.178 1.00 108.32 ? 449 VAL A CG1 1 
ATOM 9428 C CG2 . VAL E 4 437 ? 177.851 171.840 115.342 1.00 108.32 ? 449 VAL A CG2 1 
ATOM 9429 N N   . MET E 4 438 ? 177.339 170.067 119.619 1.00 116.54 ? 450 MET A N   1 
ATOM 9430 C CA  . MET E 4 438 ? 176.798 169.118 120.587 1.00 116.54 ? 450 MET A CA  1 
ATOM 9431 C C   . MET E 4 438 ? 175.753 169.759 121.489 1.00 116.54 ? 450 MET A C   1 
ATOM 9432 O O   . MET E 4 438 ? 174.827 169.079 121.948 1.00 116.54 ? 450 MET A O   1 
ATOM 9433 C CB  . MET E 4 438 ? 177.928 168.535 121.443 1.00 116.54 ? 450 MET A CB  1 
ATOM 9434 C CG  . MET E 4 438 ? 178.921 167.602 120.736 1.00 116.54 ? 450 MET A CG  1 
ATOM 9435 S SD  . MET E 4 438 ? 178.418 166.693 119.248 1.00 116.54 ? 450 MET A SD  1 
ATOM 9436 C CE  . MET E 4 438 ? 176.913 165.858 119.754 1.00 116.54 ? 450 MET A CE  1 
ATOM 9437 N N   . VAL E 4 439 ? 175.884 171.056 121.762 1.00 111.13 ? 451 VAL A N   1 
ATOM 9438 C CA  . VAL E 4 439 ? 174.989 171.754 122.679 1.00 111.13 ? 451 VAL A CA  1 
ATOM 9439 C C   . VAL E 4 439 ? 173.567 171.781 122.136 1.00 111.13 ? 451 VAL A C   1 
ATOM 9440 O O   . VAL E 4 439 ? 172.616 171.417 122.837 1.00 111.13 ? 451 VAL A O   1 
ATOM 9441 C CB  . VAL E 4 439 ? 175.490 173.183 122.953 1.00 111.13 ? 451 VAL A CB  1 
ATOM 9442 C CG1 . VAL E 4 439 ? 174.859 173.729 124.221 1.00 111.13 ? 451 VAL A CG1 1 
ATOM 9443 C CG2 . VAL E 4 439 ? 177.001 173.194 123.069 1.00 111.13 ? 451 VAL A CG2 1 
ATOM 9444 N N   . VAL E 4 440 ? 173.411 172.203 120.884 1.00 105.78 ? 452 VAL A N   1 
ATOM 9445 C CA  . VAL E 4 440 ? 172.089 172.405 120.300 1.00 105.78 ? 452 VAL A CA  1 
ATOM 9446 C C   . VAL E 4 440 ? 171.476 171.067 119.904 1.00 105.78 ? 452 VAL A C   1 
ATOM 9447 O O   . VAL E 4 440 ? 170.294 170.992 119.551 1.00 105.78 ? 452 VAL A O   1 
ATOM 9448 C CB  . VAL E 4 440 ? 172.168 173.366 119.100 1.00 105.78 ? 452 VAL A CB  1 
ATOM 9449 C CG1 . VAL E 4 440 ? 172.597 172.623 117.856 1.00 105.78 ? 452 VAL A CG1 1 
ATOM 9450 C CG2 . VAL E 4 440 ? 170.832 174.055 118.884 1.00 105.78 ? 452 VAL A CG2 1 
ATOM 9451 N N   . PHE E 4 441 ? 172.278 170.004 119.962 1.00 107.22 ? 453 PHE A N   1 
ATOM 9452 C CA  . PHE E 4 441 ? 171.800 168.671 119.609 1.00 107.22 ? 453 PHE A CA  1 
ATOM 9453 C C   . PHE E 4 441 ? 170.712 168.223 120.584 1.00 107.22 ? 453 PHE A C   1 
ATOM 9454 O O   . PHE E 4 441 ? 169.684 167.667 120.183 1.00 107.22 ? 453 PHE A O   1 
ATOM 9455 C CB  . PHE E 4 441 ? 173.000 167.709 119.597 1.00 107.22 ? 453 PHE A CB  1 
ATOM 9456 C CG  . PHE E 4 441 ? 172.719 166.325 119.039 1.00 107.22 ? 453 PHE A CG  1 
ATOM 9457 C CD1 . PHE E 4 441 ? 171.506 165.681 119.216 1.00 107.22 ? 453 PHE A CD1 1 
ATOM 9458 C CD2 . PHE E 4 441 ? 173.706 165.668 118.329 1.00 107.22 ? 453 PHE A CD2 1 
ATOM 9459 C CE1 . PHE E 4 441 ? 171.283 164.427 118.699 1.00 107.22 ? 453 PHE A CE1 1 
ATOM 9460 C CE2 . PHE E 4 441 ? 173.488 164.412 117.812 1.00 107.22 ? 453 PHE A CE2 1 
ATOM 9461 C CZ  . PHE E 4 441 ? 172.274 163.790 117.996 1.00 107.22 ? 453 PHE A CZ  1 
ATOM 9462 N N   . LYS E 4 442 ? 170.915 168.484 121.872 1.00 105.27 ? 454 LYS A N   1 
ATOM 9463 C CA  . LYS E 4 442 ? 170.057 167.933 122.916 1.00 105.27 ? 454 LYS A CA  1 
ATOM 9464 C C   . LYS E 4 442 ? 168.608 168.398 122.785 1.00 105.27 ? 454 LYS A C   1 
ATOM 9465 O O   . LYS E 4 442 ? 167.687 167.705 123.232 1.00 105.27 ? 454 LYS A O   1 
ATOM 9466 C CB  . LYS E 4 442 ? 170.632 168.302 124.289 1.00 105.27 ? 454 LYS A CB  1 
ATOM 9467 C CG  . LYS E 4 442 ? 169.664 168.222 125.457 1.00 105.27 ? 454 LYS A CG  1 
ATOM 9468 C CD  . LYS E 4 442 ? 170.156 169.053 126.629 1.00 105.27 ? 454 LYS A CD  1 
ATOM 9469 C CE  . LYS E 4 442 ? 169.981 168.311 127.942 1.00 105.27 ? 454 LYS A CE  1 
ATOM 9470 N NZ  . LYS E 4 442 ? 168.555 167.967 128.189 1.00 105.27 ? 454 LYS A NZ  1 
ATOM 9471 N N   . TYR E 4 443 ? 168.385 169.541 122.137 1.00 104.15 ? 455 TYR A N   1 
ATOM 9472 C CA  . TYR E 4 443 ? 167.069 170.169 122.131 1.00 104.15 ? 455 TYR A CA  1 
ATOM 9473 C C   . TYR E 4 443 ? 166.196 169.795 120.938 1.00 104.15 ? 455 TYR A C   1 
ATOM 9474 O O   . TYR E 4 443 ? 165.030 170.201 120.899 1.00 104.15 ? 455 TYR A O   1 
ATOM 9475 C CB  . TYR E 4 443 ? 167.211 171.695 122.164 1.00 104.15 ? 455 TYR A CB  1 
ATOM 9476 C CG  . TYR E 4 443 ? 168.097 172.221 123.272 1.00 104.15 ? 455 TYR A CG  1 
ATOM 9477 C CD1 . TYR E 4 443 ? 167.592 172.449 124.545 1.00 104.15 ? 455 TYR A CD1 1 
ATOM 9478 C CD2 . TYR E 4 443 ? 169.435 172.506 123.039 1.00 104.15 ? 455 TYR A CD2 1 
ATOM 9479 C CE1 . TYR E 4 443 ? 168.398 172.935 125.557 1.00 104.15 ? 455 TYR A CE1 1 
ATOM 9480 C CE2 . TYR E 4 443 ? 170.247 172.992 124.044 1.00 104.15 ? 455 TYR A CE2 1 
ATOM 9481 C CZ  . TYR E 4 443 ? 169.725 173.204 125.300 1.00 104.15 ? 455 TYR A CZ  1 
ATOM 9482 O OH  . TYR E 4 443 ? 170.534 173.689 126.301 1.00 104.15 ? 455 TYR A OH  1 
ATOM 9483 N N   . ILE E 4 444 ? 166.703 169.031 119.970 1.00 105.86 ? 456 ILE A N   1 
ATOM 9484 C CA  . ILE E 4 444 ? 165.979 168.832 118.716 1.00 105.86 ? 456 ILE A CA  1 
ATOM 9485 C C   . ILE E 4 444 ? 164.807 167.872 118.884 1.00 105.86 ? 456 ILE A C   1 
ATOM 9486 O O   . ILE E 4 444 ? 163.905 167.834 118.039 1.00 105.86 ? 456 ILE A O   1 
ATOM 9487 C CB  . ILE E 4 444 ? 166.920 168.344 117.600 1.00 105.86 ? 456 ILE A CB  1 
ATOM 9488 C CG1 . ILE E 4 444 ? 168.316 168.929 117.781 1.00 105.86 ? 456 ILE A CG1 1 
ATOM 9489 C CG2 . ILE E 4 444 ? 166.375 168.730 116.239 1.00 105.86 ? 456 ILE A CG2 1 
ATOM 9490 C CD1 . ILE E 4 444 ? 169.309 168.423 116.770 1.00 105.86 ? 456 ILE A CD1 1 
ATOM 9491 N N   . GLU E 4 445 ? 164.834 167.057 119.939 1.00 118.48 ? 457 GLU A N   1 
ATOM 9492 C CA  . GLU E 4 445 ? 163.701 166.216 120.325 1.00 118.48 ? 457 GLU A CA  1 
ATOM 9493 C C   . GLU E 4 445 ? 163.375 165.123 119.311 1.00 118.48 ? 457 GLU A C   1 
ATOM 9494 O O   . GLU E 4 445 ? 162.480 164.306 119.550 1.00 118.48 ? 457 GLU A O   1 
ATOM 9495 C CB  . GLU E 4 445 ? 162.450 167.068 120.567 1.00 118.48 ? 457 GLU A CB  1 
ATOM 9496 C CG  . GLU E 4 445 ? 162.118 167.300 122.031 1.00 118.48 ? 457 GLU A CG  1 
ATOM 9497 C CD  . GLU E 4 445 ? 160.814 168.054 122.216 1.00 118.48 ? 457 GLU A CD  1 
ATOM 9498 O OE1 . GLU E 4 445 ? 160.176 168.399 121.199 1.00 118.48 ? 457 GLU A OE1 1 
ATOM 9499 O OE2 . GLU E 4 445 ? 160.426 168.298 123.377 1.00 118.48 ? 457 GLU A OE2 1 
ATOM 9500 N N   . ASP E 4 446 ? 164.078 165.091 118.182 1.00 117.34 ? 458 ASP A N   1 
ATOM 9501 C CA  . ASP E 4 446 ? 163.879 164.069 117.155 1.00 117.34 ? 458 ASP A CA  1 
ATOM 9502 C C   . ASP E 4 446 ? 165.222 163.781 116.488 1.00 117.34 ? 458 ASP A C   1 
ATOM 9503 O O   . ASP E 4 446 ? 165.630 164.452 115.538 1.00 117.34 ? 458 ASP A O   1 
ATOM 9504 C CB  . ASP E 4 446 ? 162.795 164.499 116.143 1.00 117.34 ? 458 ASP A CB  1 
ATOM 9505 C CG  . ASP E 4 446 ? 162.878 165.971 115.769 1.00 117.34 ? 458 ASP A CG  1 
ATOM 9506 O OD1 . ASP E 4 446 ? 163.976 166.466 115.447 1.00 117.34 ? 458 ASP A OD1 1 
ATOM 9507 O OD2 . ASP E 4 446 ? 161.824 166.641 115.799 1.00 117.34 ? 458 ASP A OD2 1 
ATOM 9508 N N   . LYS E 4 447 ? 165.904 162.756 116.992 1.00 111.44 ? 459 LYS A N   1 
ATOM 9509 C CA  . LYS E 4 447 ? 167.231 162.398 116.512 1.00 111.44 ? 459 LYS A CA  1 
ATOM 9510 C C   . LYS E 4 447 ? 167.165 161.773 115.125 1.00 111.44 ? 459 LYS A C   1 
ATOM 9511 O O   . LYS E 4 447 ? 168.006 162.066 114.271 1.00 111.44 ? 459 LYS A O   1 
ATOM 9512 C CB  . LYS E 4 447 ? 167.908 161.433 117.489 1.00 111.44 ? 459 LYS A CB  1 
ATOM 9513 C CG  . LYS E 4 447 ? 167.713 161.783 118.957 1.00 111.44 ? 459 LYS A CG  1 
ATOM 9514 C CD  . LYS E 4 447 ? 168.079 163.228 119.252 1.00 111.44 ? 459 LYS A CD  1 
ATOM 9515 C CE  . LYS E 4 447 ? 167.187 163.807 120.336 1.00 111.44 ? 459 LYS A CE  1 
ATOM 9516 N NZ  . LYS E 4 447 ? 167.634 163.404 121.696 1.00 111.44 ? 459 LYS A NZ  1 
ATOM 9517 N N   . ASP E 4 448 ? 166.157 160.926 114.902 1.00 113.37 ? 460 ASP A N   1 
ATOM 9518 C CA  . ASP E 4 448 ? 166.070 160.027 113.753 1.00 113.37 ? 460 ASP A CA  1 
ATOM 9519 C C   . ASP E 4 448 ? 166.505 160.657 112.434 1.00 113.37 ? 460 ASP A C   1 
ATOM 9520 O O   . ASP E 4 448 ? 167.260 160.040 111.676 1.00 113.37 ? 460 ASP A O   1 
ATOM 9521 C CB  . ASP E 4 448 ? 164.643 159.476 113.632 1.00 113.37 ? 460 ASP A CB  1 
ATOM 9522 C CG  . ASP E 4 448 ? 163.639 160.529 113.201 1.00 113.37 ? 460 ASP A CG  1 
ATOM 9523 O OD1 . ASP E 4 448 ? 163.843 161.716 113.531 1.00 113.37 ? 460 ASP A OD1 1 
ATOM 9524 O OD2 . ASP E 4 448 ? 162.642 160.168 112.541 1.00 113.37 ? 460 ASP A OD2 1 
ATOM 9525 N N   . VAL E 4 449 ? 166.051 161.880 112.152 1.00 107.79 ? 461 VAL A N   1 
ATOM 9526 C CA  . VAL E 4 449 ? 166.392 162.522 110.884 1.00 107.79 ? 461 VAL A CA  1 
ATOM 9527 C C   . VAL E 4 449 ? 167.888 162.792 110.807 1.00 107.79 ? 461 VAL A C   1 
ATOM 9528 O O   . VAL E 4 449 ? 168.497 162.696 109.734 1.00 107.79 ? 461 VAL A O   1 
ATOM 9529 C CB  . VAL E 4 449 ? 165.574 163.813 110.702 1.00 107.79 ? 461 VAL A CB  1 
ATOM 9530 C CG1 . VAL E 4 449 ? 165.850 164.434 109.340 1.00 107.79 ? 461 VAL A CG1 1 
ATOM 9531 C CG2 . VAL E 4 449 ? 164.102 163.516 110.865 1.00 107.79 ? 461 VAL A CG2 1 
ATOM 9532 N N   . PHE E 4 450 ? 168.502 163.134 111.940 1.00 104.25 ? 462 PHE A N   1 
ATOM 9533 C CA  . PHE E 4 450 ? 169.934 163.414 111.950 1.00 104.25 ? 462 PHE A CA  1 
ATOM 9534 C C   . PHE E 4 450 ? 170.728 162.181 111.533 1.00 104.25 ? 462 PHE A C   1 
ATOM 9535 O O   . PHE E 4 450 ? 171.651 162.270 110.718 1.00 104.25 ? 462 PHE A O   1 
ATOM 9536 C CB  . PHE E 4 450 ? 170.365 163.905 113.335 1.00 104.25 ? 462 PHE A CB  1 
ATOM 9537 C CG  . PHE E 4 450 ? 171.746 164.504 113.371 1.00 104.25 ? 462 PHE A CG  1 
ATOM 9538 C CD1 . PHE E 4 450 ? 172.411 164.827 112.201 1.00 104.25 ? 462 PHE A CD1 1 
ATOM 9539 C CD2 . PHE E 4 450 ? 172.376 164.746 114.577 1.00 104.25 ? 462 PHE A CD2 1 
ATOM 9540 C CE1 . PHE E 4 450 ? 173.678 165.373 112.235 1.00 104.25 ? 462 PHE A CE1 1 
ATOM 9541 C CE2 . PHE E 4 450 ? 173.643 165.296 114.614 1.00 104.25 ? 462 PHE A CE2 1 
ATOM 9542 C CZ  . PHE E 4 450 ? 174.293 165.609 113.442 1.00 104.25 ? 462 PHE A CZ  1 
ATOM 9543 N N   . GLN E 4 451 ? 170.365 161.010 112.064 1.00 107.94 ? 463 GLN A N   1 
ATOM 9544 C CA  . GLN E 4 451 ? 171.065 159.785 111.686 1.00 107.94 ? 463 GLN A CA  1 
ATOM 9545 C C   . GLN E 4 451 ? 170.933 159.505 110.194 1.00 107.94 ? 463 GLN A C   1 
ATOM 9546 O O   . GLN E 4 451 ? 171.892 159.074 109.547 1.00 107.94 ? 463 GLN A O   1 
ATOM 9547 C CB  . GLN E 4 451 ? 170.555 158.594 112.503 1.00 107.94 ? 463 GLN A CB  1 
ATOM 9548 C CG  . GLN E 4 451 ? 171.165 158.480 113.895 1.00 107.94 ? 463 GLN A CG  1 
ATOM 9549 C CD  . GLN E 4 451 ? 170.361 159.199 114.953 1.00 107.94 ? 463 GLN A CD  1 
ATOM 9550 O OE1 . GLN E 4 451 ? 169.284 159.721 114.678 1.00 107.94 ? 463 GLN A OE1 1 
ATOM 9551 N NE2 . GLN E 4 451 ? 170.881 159.231 116.175 1.00 107.94 ? 463 GLN A NE2 1 
ATOM 9552 N N   . LYS E 4 452 ? 169.749 159.742 109.631 1.00 109.41 ? 464 LYS A N   1 
ATOM 9553 C CA  . LYS E 4 452 ? 169.547 159.548 108.200 1.00 109.41 ? 464 LYS A CA  1 
ATOM 9554 C C   . LYS E 4 452 ? 170.449 160.467 107.388 1.00 109.41 ? 464 LYS A C   1 
ATOM 9555 O O   . LYS E 4 452 ? 171.343 159.999 106.677 1.00 109.41 ? 464 LYS A O   1 
ATOM 9556 C CB  . LYS E 4 452 ? 168.085 159.790 107.816 1.00 109.41 ? 464 LYS A CB  1 
ATOM 9557 C CG  . LYS E 4 452 ? 167.068 159.107 108.708 1.00 109.41 ? 464 LYS A CG  1 
ATOM 9558 C CD  . LYS E 4 452 ? 167.012 157.614 108.444 1.00 109.41 ? 464 LYS A CD  1 
ATOM 9559 C CE  . LYS E 4 452 ? 165.610 157.078 108.676 1.00 109.41 ? 464 LYS A CE  1 
ATOM 9560 N NZ  . LYS E 4 452 ? 164.593 157.876 107.936 1.00 109.41 ? 464 LYS A NZ  1 
ATOM 9561 N N   . PHE E 4 453 ? 170.235 161.780 107.508 1.00 106.25 ? 465 PHE A N   1 
ATOM 9562 C CA  . PHE E 4 453 ? 170.924 162.726 106.636 1.00 106.25 ? 465 PHE A CA  1 
ATOM 9563 C C   . PHE E 4 453 ? 172.424 162.760 106.887 1.00 106.25 ? 465 PHE A C   1 
ATOM 9564 O O   . PHE E 4 453 ? 173.201 162.997 105.955 1.00 106.25 ? 465 PHE A O   1 
ATOM 9565 C CB  . PHE E 4 453 ? 170.319 164.120 106.798 1.00 106.25 ? 465 PHE A CB  1 
ATOM 9566 C CG  . PHE E 4 453 ? 169.495 164.554 105.624 1.00 106.25 ? 465 PHE A CG  1 
ATOM 9567 C CD1 . PHE E 4 453 ? 170.069 164.665 104.369 1.00 106.25 ? 465 PHE A CD1 1 
ATOM 9568 C CD2 . PHE E 4 453 ? 168.152 164.852 105.770 1.00 106.25 ? 465 PHE A CD2 1 
ATOM 9569 C CE1 . PHE E 4 453 ? 169.320 165.064 103.282 1.00 106.25 ? 465 PHE A CE1 1 
ATOM 9570 C CE2 . PHE E 4 453 ? 167.395 165.249 104.684 1.00 106.25 ? 465 PHE A CE2 1 
ATOM 9571 C CZ  . PHE E 4 453 ? 167.981 165.357 103.439 1.00 106.25 ? 465 PHE A CZ  1 
ATOM 9572 N N   . TYR E 4 454 ? 172.856 162.540 108.131 1.00 102.37 ? 466 TYR A N   1 
ATOM 9573 C CA  . TYR E 4 454 ? 174.287 162.438 108.395 1.00 102.37 ? 466 TYR A CA  1 
ATOM 9574 C C   . TYR E 4 454 ? 174.884 161.245 107.664 1.00 102.37 ? 466 TYR A C   1 
ATOM 9575 O O   . TYR E 4 454 ? 175.884 161.375 106.953 1.00 102.37 ? 466 TYR A O   1 
ATOM 9576 C CB  . TYR E 4 454 ? 174.544 162.326 109.898 1.00 102.37 ? 466 TYR A CB  1 
ATOM 9577 C CG  . TYR E 4 454 ? 175.980 162.562 110.310 1.00 102.37 ? 466 TYR A CG  1 
ATOM 9578 C CD1 . TYR E 4 454 ? 176.898 163.119 109.430 1.00 102.37 ? 466 TYR A CD1 1 
ATOM 9579 C CD2 . TYR E 4 454 ? 176.413 162.236 111.586 1.00 102.37 ? 466 TYR A CD2 1 
ATOM 9580 C CE1 . TYR E 4 454 ? 178.208 163.337 109.809 1.00 102.37 ? 466 TYR A CE1 1 
ATOM 9581 C CE2 . TYR E 4 454 ? 177.719 162.449 111.973 1.00 102.37 ? 466 TYR A CE2 1 
ATOM 9582 C CZ  . TYR E 4 454 ? 178.612 163.000 111.082 1.00 102.37 ? 466 TYR A CZ  1 
ATOM 9583 O OH  . TYR E 4 454 ? 179.915 163.214 111.466 1.00 102.37 ? 466 TYR A OH  1 
ATOM 9584 N N   . ALA E 4 455 ? 174.256 160.076 107.804 1.00 104.67 ? 467 ALA A N   1 
ATOM 9585 C CA  . ALA E 4 455 ? 174.807 158.855 107.226 1.00 104.67 ? 467 ALA A CA  1 
ATOM 9586 C C   . ALA E 4 455 ? 174.871 158.940 105.706 1.00 104.67 ? 467 ALA A C   1 
ATOM 9587 O O   . ALA E 4 455 ? 175.845 158.493 105.089 1.00 104.67 ? 467 ALA A O   1 
ATOM 9588 C CB  . ALA E 4 455 ? 173.977 157.648 107.663 1.00 104.67 ? 467 ALA A CB  1 
ATOM 9589 N N   . LYS E 4 456 ? 173.833 159.504 105.080 1.00 107.54 ? 468 LYS A N   1 
ATOM 9590 C CA  . LYS E 4 456 ? 173.780 159.548 103.622 1.00 107.54 ? 468 LYS A CA  1 
ATOM 9591 C C   . LYS E 4 456 ? 174.992 160.257 103.038 1.00 107.54 ? 468 LYS A C   1 
ATOM 9592 O O   . LYS E 4 456 ? 175.705 159.704 102.195 1.00 107.54 ? 468 LYS A O   1 
ATOM 9593 C CB  . LYS E 4 456 ? 172.496 160.242 103.158 1.00 107.54 ? 468 LYS A CB  1 
ATOM 9594 C CG  . LYS E 4 456 ? 171.219 159.567 103.608 1.00 107.54 ? 468 LYS A CG  1 
ATOM 9595 C CD  . LYS E 4 456 ? 170.154 159.626 102.529 1.00 107.54 ? 468 LYS A CD  1 
ATOM 9596 C CE  . LYS E 4 456 ? 168.950 158.778 102.901 1.00 107.54 ? 468 LYS A CE  1 
ATOM 9597 N NZ  . LYS E 4 456 ? 167.667 159.413 102.497 1.00 107.54 ? 468 LYS A NZ  1 
ATOM 9598 N N   . MET E 4 457 ? 175.251 161.482 103.491 1.00 114.47 ? 469 MET A N   1 
ATOM 9599 C CA  . MET E 4 457 ? 176.381 162.229 102.954 1.00 114.47 ? 469 MET A CA  1 
ATOM 9600 C C   . MET E 4 457 ? 177.683 161.782 103.608 1.00 114.47 ? 469 MET A C   1 
ATOM 9601 O O   . MET E 4 457 ? 178.774 162.070 103.103 1.00 114.47 ? 469 MET A O   1 
ATOM 9602 C CB  . MET E 4 457 ? 176.162 163.729 103.137 1.00 114.47 ? 469 MET A CB  1 
ATOM 9603 C CG  . MET E 4 457 ? 175.537 164.410 101.923 1.00 114.47 ? 469 MET A CG  1 
ATOM 9604 S SD  . MET E 4 457 ? 176.144 166.081 101.634 1.00 114.47 ? 469 MET A SD  1 
ATOM 9605 C CE  . MET E 4 457 ? 177.897 165.759 101.496 1.00 114.47 ? 469 MET A CE  1 
ATOM 9606 N N   . LEU E 4 458 ? 177.587 161.098 104.751 1.00 109.85 ? 470 LEU A N   1 
ATOM 9607 C CA  . LEU E 4 458 ? 178.765 160.465 105.333 1.00 109.85 ? 470 LEU A CA  1 
ATOM 9608 C C   . LEU E 4 458 ? 179.306 159.414 104.378 1.00 109.85 ? 470 LEU A C   1 
ATOM 9609 O O   . LEU E 4 458 ? 180.520 159.297 104.182 1.00 109.85 ? 470 LEU A O   1 
ATOM 9610 C CB  . LEU E 4 458 ? 178.423 159.842 106.692 1.00 109.85 ? 470 LEU A CB  1 
ATOM 9611 C CG  . LEU E 4 458 ? 179.333 158.776 107.313 1.00 109.85 ? 470 LEU A CG  1 
ATOM 9612 C CD1 . LEU E 4 458 ? 180.773 159.252 107.391 1.00 109.85 ? 470 LEU A CD1 1 
ATOM 9613 C CD2 . LEU E 4 458 ? 178.833 158.393 108.696 1.00 109.85 ? 470 LEU A CD2 1 
ATOM 9614 N N   . ALA E 4 459 ? 178.405 158.645 103.765 1.00 116.32 ? 471 ALA A N   1 
ATOM 9615 C CA  . ALA E 4 459 ? 178.782 157.618 102.803 1.00 116.32 ? 471 ALA A CA  1 
ATOM 9616 C C   . ALA E 4 459 ? 179.530 158.239 101.633 1.00 116.32 ? 471 ALA A C   1 
ATOM 9617 O O   . ALA E 4 459 ? 180.524 157.682 101.157 1.00 116.32 ? 471 ALA A O   1 
ATOM 9618 C CB  . ALA E 4 459 ? 177.545 156.864 102.311 1.00 116.32 ? 471 ALA A CB  1 
ATOM 9619 N N   . LYS E 4 460 ? 179.057 159.395 101.164 1.00 113.79 ? 472 LYS A N   1 
ATOM 9620 C CA  . LYS E 4 460 ? 179.772 160.130 100.127 1.00 113.79 ? 472 LYS A CA  1 
ATOM 9621 C C   . LYS E 4 460 ? 181.158 160.535 100.613 1.00 113.79 ? 472 LYS A C   1 
ATOM 9622 O O   . LYS E 4 460 ? 182.134 160.499 99.857  1.00 113.79 ? 472 LYS A O   1 
ATOM 9623 C CB  . LYS E 4 460 ? 178.965 161.362 99.709  1.00 113.79 ? 472 LYS A CB  1 
ATOM 9624 C CG  . LYS E 4 460 ? 177.460 161.147 99.673  1.00 113.79 ? 472 LYS A CG  1 
ATOM 9625 C CD  . LYS E 4 460 ? 177.059 160.157 98.594  1.00 113.79 ? 472 LYS A CD  1 
ATOM 9626 C CE  . LYS E 4 460 ? 175.825 159.370 99.002  1.00 113.79 ? 472 LYS A CE  1 
ATOM 9627 N NZ  . LYS E 4 460 ? 174.854 160.215 99.750  1.00 113.79 ? 472 LYS A NZ  1 
ATOM 9628 N N   . ARG E 4 461 ? 181.255 160.927 101.885 1.00 113.48 ? 473 ARG A N   1 
ATOM 9629 C CA  . ARG E 4 461 ? 182.528 161.366 102.443 1.00 113.48 ? 473 ARG A CA  1 
ATOM 9630 C C   . ARG E 4 461 ? 183.528 160.216 102.526 1.00 113.48 ? 473 ARG A C   1 
ATOM 9631 O O   . ARG E 4 461 ? 184.675 160.339 102.085 1.00 113.48 ? 473 ARG A O   1 
ATOM 9632 C CB  . ARG E 4 461 ? 182.300 161.983 103.823 1.00 113.48 ? 473 ARG A CB  1 
ATOM 9633 C CG  . ARG E 4 461 ? 183.464 162.823 104.318 1.00 113.48 ? 473 ARG A CG  1 
ATOM 9634 C CD  . ARG E 4 461 ? 183.204 163.657 105.591 1.00 113.48 ? 473 ARG A CD  1 
ATOM 9635 N NE  . ARG E 4 461 ? 182.246 163.112 106.551 1.00 113.48 ? 473 ARG A NE  1 
ATOM 9636 C CZ  . ARG E 4 461 ? 180.925 163.183 106.444 1.00 113.48 ? 473 ARG A CZ  1 
ATOM 9637 N NH1 . ARG E 4 461 ? 180.343 163.817 105.438 1.00 113.48 ? 473 ARG A NH1 1 
ATOM 9638 N NH2 . ARG E 4 461 ? 180.168 162.625 107.384 1.00 113.48 ? 473 ARG A NH2 1 
ATOM 9639 N N   . LEU E 4 462 ? 183.105 159.088 103.100 1.00 116.13 ? 474 LEU A N   1 
ATOM 9640 C CA  . LEU E 4 462 ? 184.017 157.971 103.330 1.00 116.13 ? 474 LEU A CA  1 
ATOM 9641 C C   . LEU E 4 462 ? 184.515 157.372 102.019 1.00 116.13 ? 474 LEU A C   1 
ATOM 9642 O O   . LEU E 4 462 ? 185.692 157.018 101.889 1.00 116.13 ? 474 LEU A O   1 
ATOM 9643 C CB  . LEU E 4 462 ? 183.332 156.904 104.186 1.00 116.13 ? 474 LEU A CB  1 
ATOM 9644 C CG  . LEU E 4 462 ? 183.257 157.176 105.690 1.00 116.13 ? 474 LEU A CG  1 
ATOM 9645 C CD1 . LEU E 4 462 ? 183.080 155.877 106.460 1.00 116.13 ? 474 LEU A CD1 1 
ATOM 9646 C CD2 . LEU E 4 462 ? 184.496 157.918 106.168 1.00 116.13 ? 474 LEU A CD2 1 
ATOM 9647 N N   . VAL E 4 463 ? 183.624 157.243 101.037 1.00 115.55 ? 475 VAL A N   1 
ATOM 9648 C CA  . VAL E 4 463 ? 183.966 156.638 99.754  1.00 115.55 ? 475 VAL A CA  1 
ATOM 9649 C C   . VAL E 4 463 ? 185.040 157.465 99.060  1.00 115.55 ? 475 VAL A C   1 
ATOM 9650 O O   . VAL E 4 463 ? 186.023 156.921 98.545  1.00 115.55 ? 475 VAL A O   1 
ATOM 9651 C CB  . VAL E 4 463 ? 182.720 156.492 98.861  1.00 115.55 ? 475 VAL A CB  1 
ATOM 9652 C CG1 . VAL E 4 463 ? 183.123 156.197 97.425  1.00 115.55 ? 475 VAL A CG1 1 
ATOM 9653 C CG2 . VAL E 4 463 ? 181.816 155.393 99.392  1.00 115.55 ? 475 VAL A CG2 1 
ATOM 9654 N N   . HIS E 4 464 ? 184.868 158.784 99.056  1.00 117.85 ? 476 HIS A N   1 
ATOM 9655 C CA  . HIS E 4 464 ? 185.785 159.678 98.369  1.00 117.85 ? 476 HIS A CA  1 
ATOM 9656 C C   . HIS E 4 464 ? 186.876 160.233 99.272  1.00 117.85 ? 476 HIS A C   1 
ATOM 9657 O O   . HIS E 4 464 ? 187.693 161.035 98.804  1.00 117.85 ? 476 HIS A O   1 
ATOM 9658 C CB  . HIS E 4 464 ? 185.015 160.841 97.726  1.00 117.85 ? 476 HIS A CB  1 
ATOM 9659 C CG  . HIS E 4 464 ? 183.808 160.414 96.948  1.00 117.85 ? 476 HIS A CG  1 
ATOM 9660 N ND1 . HIS E 4 464 ? 182.698 159.852 97.540  1.00 117.85 ? 476 HIS A ND1 1 
ATOM 9661 C CD2 . HIS E 4 464 ? 183.541 160.463 95.621  1.00 117.85 ? 476 HIS A CD2 1 
ATOM 9662 C CE1 . HIS E 4 464 ? 181.798 159.576 96.614  1.00 117.85 ? 476 HIS A CE1 1 
ATOM 9663 N NE2 . HIS E 4 464 ? 182.285 159.937 95.440  1.00 117.85 ? 476 HIS A NE2 1 
ATOM 9664 N N   . GLN E 4 465 ? 186.916 159.835 100.544 1.00 122.80 ? 477 GLN A N   1 
ATOM 9665 C CA  . GLN E 4 465 ? 187.894 160.280 101.538 1.00 122.80 ? 477 GLN A CA  1 
ATOM 9666 C C   . GLN E 4 465 ? 187.886 161.794 101.704 1.00 122.80 ? 477 GLN A C   1 
ATOM 9667 O O   . GLN E 4 465 ? 188.943 162.382 101.982 1.00 122.80 ? 477 GLN A O   1 
ATOM 9668 C CB  . GLN E 4 465 ? 189.317 159.820 101.202 1.00 122.80 ? 477 GLN A CB  1 
ATOM 9669 C CG  . GLN E 4 465 ? 189.468 158.314 101.073 1.00 122.80 ? 477 GLN A CG  1 
ATOM 9670 C CD  . GLN E 4 465 ? 189.414 157.608 102.413 1.00 122.80 ? 477 GLN A CD  1 
ATOM 9671 O OE1 . GLN E 4 465 ? 190.195 157.907 103.317 1.00 122.80 ? 477 GLN A OE1 1 
ATOM 9672 N NE2 . GLN E 4 465 ? 188.489 156.665 102.549 1.00 122.80 ? 477 GLN A NE2 1 
ATOM 9673 N N   . ASN E 4 466 ? 186.734 162.447 101.546 1.00 122.61 ? 478 ASN A N   1 
ATOM 9674 C CA  . ASN E 4 466 ? 186.655 163.907 101.583 1.00 122.61 ? 478 ASN A CA  1 
ATOM 9675 C C   . ASN E 4 466 ? 186.535 164.384 103.031 1.00 122.61 ? 478 ASN A C   1 
ATOM 9676 O O   . ASN E 4 466 ? 185.556 165.009 103.446 1.00 122.61 ? 478 ASN A O   1 
ATOM 9677 C CB  . ASN E 4 466 ? 185.490 164.395 100.734 1.00 122.61 ? 478 ASN A CB  1 
ATOM 9678 C CG  . ASN E 4 466 ? 185.935 164.933 99.390  1.00 122.61 ? 478 ASN A CG  1 
ATOM 9679 O OD1 . ASN E 4 466 ? 187.111 164.853 99.036  1.00 122.61 ? 478 ASN A OD1 1 
ATOM 9680 N ND2 . ASN E 4 466 ? 184.995 165.487 98.633  1.00 122.61 ? 478 ASN A ND2 1 
ATOM 9681 N N   . SER E 4 467 ? 187.575 164.089 103.804 1.00 121.30 ? 479 SER A N   1 
ATOM 9682 C CA  . SER E 4 467 ? 187.625 164.494 105.202 1.00 121.30 ? 479 SER A CA  1 
ATOM 9683 C C   . SER E 4 467 ? 189.078 164.498 105.652 1.00 121.30 ? 479 SER A C   1 
ATOM 9684 O O   . SER E 4 467 ? 189.911 163.758 105.121 1.00 121.30 ? 479 SER A O   1 
ATOM 9685 C CB  . SER E 4 467 ? 186.786 163.568 106.090 1.00 121.30 ? 479 SER A CB  1 
ATOM 9686 O OG  . SER E 4 467 ? 187.349 163.451 107.385 1.00 121.30 ? 479 SER A OG  1 
ATOM 9687 N N   . ALA E 4 468 ? 189.371 165.348 106.634 1.00 117.30 ? 480 ALA A N   1 
ATOM 9688 C CA  . ALA E 4 468 ? 190.697 165.474 107.206 1.00 117.30 ? 480 ALA A CA  1 
ATOM 9689 C C   . ALA E 4 468 ? 190.650 165.098 108.688 1.00 117.30 ? 480 ALA A C   1 
ATOM 9690 O O   . ALA E 4 468 ? 189.588 165.178 109.328 1.00 117.30 ? 480 ALA A O   1 
ATOM 9691 C CB  . ALA E 4 468 ? 191.213 166.897 106.974 1.00 117.30 ? 480 ALA A CB  1 
ATOM 9692 N N   . SER E 4 469 ? 191.803 164.696 109.234 1.00 120.39 ? 481 SER A N   1 
ATOM 9693 C CA  . SER E 4 469 ? 191.915 164.367 110.651 1.00 120.39 ? 481 SER A CA  1 
ATOM 9694 C C   . SER E 4 469 ? 190.881 163.322 111.059 1.00 120.39 ? 481 SER A C   1 
ATOM 9695 O O   . SER E 4 469 ? 189.929 163.632 111.784 1.00 120.39 ? 481 SER A O   1 
ATOM 9696 C CB  . SER E 4 469 ? 191.782 165.633 111.498 1.00 120.39 ? 481 SER A CB  1 
ATOM 9697 O OG  . SER E 4 469 ? 190.478 165.751 112.023 1.00 120.39 ? 481 SER A OG  1 
ATOM 9698 N N   . ASP E 4 470 ? 191.059 162.089 110.570 1.00 120.29 ? 482 ASP A N   1 
ATOM 9699 C CA  . ASP E 4 470 ? 190.072 161.023 110.749 1.00 120.29 ? 482 ASP A CA  1 
ATOM 9700 C C   . ASP E 4 470 ? 189.595 160.900 112.194 1.00 120.29 ? 482 ASP A C   1 
ATOM 9701 O O   . ASP E 4 470 ? 188.466 160.463 112.444 1.00 120.29 ? 482 ASP A O   1 
ATOM 9702 C CB  . ASP E 4 470 ? 190.663 159.697 110.262 1.00 120.29 ? 482 ASP A CB  1 
ATOM 9703 C CG  . ASP E 4 470 ? 189.673 158.546 110.334 1.00 120.29 ? 482 ASP A CG  1 
ATOM 9704 O OD1 . ASP E 4 470 ? 189.408 158.044 111.447 1.00 120.29 ? 482 ASP A OD1 1 
ATOM 9705 O OD2 . ASP E 4 470 ? 189.157 158.140 109.272 1.00 120.29 ? 482 ASP A OD2 1 
ATOM 9706 N N   . ASP E 4 471 ? 190.432 161.275 113.160 1.00 119.36 ? 483 ASP A N   1 
ATOM 9707 C CA  . ASP E 4 471 ? 190.049 161.152 114.562 1.00 119.36 ? 483 ASP A CA  1 
ATOM 9708 C C   . ASP E 4 471 ? 188.868 162.056 114.903 1.00 119.36 ? 483 ASP A C   1 
ATOM 9709 O O   . ASP E 4 471 ? 188.021 161.688 115.724 1.00 119.36 ? 483 ASP A O   1 
ATOM 9710 C CB  . ASP E 4 471 ? 191.236 161.469 115.475 1.00 119.36 ? 483 ASP A CB  1 
ATOM 9711 C CG  . ASP E 4 471 ? 191.973 162.725 115.060 1.00 119.36 ? 483 ASP A CG  1 
ATOM 9712 O OD1 . ASP E 4 471 ? 191.557 163.361 114.070 1.00 119.36 ? 483 ASP A OD1 1 
ATOM 9713 O OD2 . ASP E 4 471 ? 192.965 163.080 115.729 1.00 119.36 ? 483 ASP A OD2 1 
ATOM 9714 N N   . ALA E 4 472 ? 188.799 163.233 114.273 1.00 117.14 ? 484 ALA A N   1 
ATOM 9715 C CA  . ALA E 4 472 ? 187.762 164.209 114.599 1.00 117.14 ? 484 ALA A CA  1 
ATOM 9716 C C   . ALA E 4 472 ? 186.358 163.653 114.395 1.00 117.14 ? 484 ALA A C   1 
ATOM 9717 O O   . ALA E 4 472 ? 185.495 163.778 115.271 1.00 117.14 ? 484 ALA A O   1 
ATOM 9718 C CB  . ALA E 4 472 ? 187.960 165.473 113.762 1.00 117.14 ? 484 ALA A CB  1 
ATOM 9719 N N   . GLU E 4 473 ? 186.102 163.049 113.235 1.00 115.95 ? 485 GLU A N   1 
ATOM 9720 C CA  . GLU E 4 473 ? 184.815 162.399 113.018 1.00 115.95 ? 485 GLU A CA  1 
ATOM 9721 C C   . GLU E 4 473 ? 184.639 161.231 113.979 1.00 115.95 ? 485 GLU A C   1 
ATOM 9722 O O   . GLU E 4 473 ? 183.580 161.068 114.590 1.00 115.95 ? 485 GLU A O   1 
ATOM 9723 C CB  . GLU E 4 473 ? 184.674 161.941 111.562 1.00 115.95 ? 485 GLU A CB  1 
ATOM 9724 C CG  . GLU E 4 473 ? 185.931 161.383 110.903 1.00 115.95 ? 485 GLU A CG  1 
ATOM 9725 C CD  . GLU E 4 473 ? 186.934 162.453 110.492 1.00 115.95 ? 485 GLU A CD  1 
ATOM 9726 O OE1 . GLU E 4 473 ? 187.436 162.381 109.352 1.00 115.95 ? 485 GLU A OE1 1 
ATOM 9727 O OE2 . GLU E 4 473 ? 187.227 163.360 111.299 1.00 115.95 ? 485 GLU A OE2 1 
ATOM 9728 N N   . ALA E 4 474 ? 185.686 160.418 114.143 1.00 115.84 ? 486 ALA A N   1 
ATOM 9729 C CA  . ALA E 4 474 ? 185.647 159.349 115.135 1.00 115.84 ? 486 ALA A CA  1 
ATOM 9730 C C   . ALA E 4 474 ? 185.340 159.906 116.518 1.00 115.84 ? 486 ALA A C   1 
ATOM 9731 O O   . ALA E 4 474 ? 184.696 159.246 117.342 1.00 115.84 ? 486 ALA A O   1 
ATOM 9732 C CB  . ALA E 4 474 ? 186.972 158.585 115.138 1.00 115.84 ? 486 ALA A CB  1 
ATOM 9733 N N   . SER E 4 475 ? 185.797 161.128 116.789 1.00 113.40 ? 487 SER A N   1 
ATOM 9734 C CA  . SER E 4 475 ? 185.424 161.826 118.011 1.00 113.40 ? 487 SER A CA  1 
ATOM 9735 C C   . SER E 4 475 ? 183.941 162.175 117.992 1.00 113.40 ? 487 SER A C   1 
ATOM 9736 O O   . SER E 4 475 ? 183.294 162.202 119.044 1.00 113.40 ? 487 SER A O   1 
ATOM 9737 C CB  . SER E 4 475 ? 186.272 163.086 118.194 1.00 113.40 ? 487 SER A CB  1 
ATOM 9738 O OG  . SER E 4 475 ? 185.571 164.240 117.762 1.00 113.40 ? 487 SER A OG  1 
ATOM 9739 N N   . MET E 4 476 ? 183.390 162.449 116.806 1.00 115.12 ? 488 MET A N   1 
ATOM 9740 C CA  . MET E 4 476 ? 181.982 162.824 116.719 1.00 115.12 ? 488 MET A CA  1 
ATOM 9741 C C   . MET E 4 476 ? 181.064 161.672 117.116 1.00 115.12 ? 488 MET A C   1 
ATOM 9742 O O   . MET E 4 476 ? 180.134 161.870 117.905 1.00 115.12 ? 488 MET A O   1 
ATOM 9743 C CB  . MET E 4 476 ? 181.649 163.322 115.311 1.00 115.12 ? 488 MET A CB  1 
ATOM 9744 C CG  . MET E 4 476 ? 180.206 163.094 114.885 1.00 115.12 ? 488 MET A CG  1 
ATOM 9745 S SD  . MET E 4 476 ? 179.019 164.035 115.864 1.00 115.12 ? 488 MET A SD  1 
ATOM 9746 C CE  . MET E 4 476 ? 178.973 165.574 114.953 1.00 115.12 ? 488 MET A CE  1 
ATOM 9747 N N   . ILE E 4 477 ? 181.295 160.463 116.590 1.00 113.99 ? 489 ILE A N   1 
ATOM 9748 C CA  . ILE E 4 477 ? 180.504 159.333 117.071 1.00 113.99 ? 489 ILE A CA  1 
ATOM 9749 C C   . ILE E 4 477 ? 180.822 159.051 118.532 1.00 113.99 ? 489 ILE A C   1 
ATOM 9750 O O   . ILE E 4 477 ? 179.973 158.537 119.269 1.00 113.99 ? 489 ILE A O   1 
ATOM 9751 C CB  . ILE E 4 477 ? 180.682 158.063 116.206 1.00 113.99 ? 489 ILE A CB  1 
ATOM 9752 C CG1 . ILE E 4 477 ? 180.752 158.377 114.709 1.00 113.99 ? 489 ILE A CG1 1 
ATOM 9753 C CG2 . ILE E 4 477 ? 179.551 157.079 116.469 1.00 113.99 ? 489 ILE A CG2 1 
ATOM 9754 C CD1 . ILE E 4 477 ? 182.141 158.512 114.164 1.00 113.99 ? 489 ILE A CD1 1 
ATOM 9755 N N   . SER E 4 478 ? 182.036 159.381 118.980 1.00 113.59 ? 490 SER A N   1 
ATOM 9756 C CA  . SER E 4 478 ? 182.325 159.298 120.408 1.00 113.59 ? 490 SER A CA  1 
ATOM 9757 C C   . SER E 4 478 ? 181.456 160.274 121.193 1.00 113.59 ? 490 SER A C   1 
ATOM 9758 O O   . SER E 4 478 ? 180.936 159.930 122.261 1.00 113.59 ? 490 SER A O   1 
ATOM 9759 C CB  . SER E 4 478 ? 183.807 159.562 120.670 1.00 113.59 ? 490 SER A CB  1 
ATOM 9760 O OG  . SER E 4 478 ? 184.063 160.949 120.789 1.00 113.59 ? 490 SER A OG  1 
ATOM 9761 N N   . LYS E 4 479 ? 181.288 161.497 120.680 1.00 110.96 ? 491 LYS A N   1 
ATOM 9762 C CA  . LYS E 4 479 ? 180.280 162.391 121.240 1.00 110.96 ? 491 LYS A CA  1 
ATOM 9763 C C   . LYS E 4 479 ? 178.882 161.819 121.044 1.00 110.96 ? 491 LYS A C   1 
ATOM 9764 O O   . LYS E 4 479 ? 178.041 161.888 121.948 1.00 110.96 ? 491 LYS A O   1 
ATOM 9765 C CB  . LYS E 4 479 ? 180.385 163.780 120.610 1.00 110.96 ? 491 LYS A CB  1 
ATOM 9766 C CG  . LYS E 4 479 ? 181.399 164.698 121.273 1.00 110.96 ? 491 LYS A CG  1 
ATOM 9767 C CD  . LYS E 4 479 ? 182.602 164.938 120.379 1.00 110.96 ? 491 LYS A CD  1 
ATOM 9768 C CE  . LYS E 4 479 ? 183.524 165.997 120.959 1.00 110.96 ? 491 LYS A CE  1 
ATOM 9769 N NZ  . LYS E 4 479 ? 184.689 166.261 120.070 1.00 110.96 ? 491 LYS A NZ  1 
ATOM 9770 N N   . LEU E 4 480 ? 178.616 161.252 119.864 1.00 110.85 ? 492 LEU A N   1 
ATOM 9771 C CA  . LEU E 4 480 ? 177.364 160.537 119.650 1.00 110.85 ? 492 LEU A CA  1 
ATOM 9772 C C   . LEU E 4 480 ? 177.228 159.343 120.582 1.00 110.85 ? 492 LEU A C   1 
ATOM 9773 O O   . LEU E 4 480 ? 176.114 159.036 121.017 1.00 110.85 ? 492 LEU A O   1 
ATOM 9774 C CB  . LEU E 4 480 ? 177.259 160.078 118.195 1.00 110.85 ? 492 LEU A CB  1 
ATOM 9775 C CG  . LEU E 4 480 ? 176.489 160.985 117.238 1.00 110.85 ? 492 LEU A CG  1 
ATOM 9776 C CD1 . LEU E 4 480 ? 176.171 160.252 115.948 1.00 110.85 ? 492 LEU A CD1 1 
ATOM 9777 C CD2 . LEU E 4 480 ? 175.213 161.448 117.904 1.00 110.85 ? 492 LEU A CD2 1 
ATOM 9778 N N   . LYS E 4 481 ? 178.334 158.665 120.895 1.00 114.48 ? 493 LYS A N   1 
ATOM 9779 C CA  . LYS E 4 481 ? 178.295 157.596 121.885 1.00 114.48 ? 493 LYS A CA  1 
ATOM 9780 C C   . LYS E 4 481 ? 177.872 158.141 123.243 1.00 114.48 ? 493 LYS A C   1 
ATOM 9781 O O   . LYS E 4 481 ? 177.095 157.510 123.968 1.00 114.48 ? 493 LYS A O   1 
ATOM 9782 C CB  . LYS E 4 481 ? 179.660 156.909 121.970 1.00 114.48 ? 493 LYS A CB  1 
ATOM 9783 C CG  . LYS E 4 481 ? 179.809 155.951 123.139 1.00 114.48 ? 493 LYS A CG  1 
ATOM 9784 C CD  . LYS E 4 481 ? 180.388 154.620 122.689 1.00 114.48 ? 493 LYS A CD  1 
ATOM 9785 C CE  . LYS E 4 481 ? 179.525 153.988 121.609 1.00 114.48 ? 493 LYS A CE  1 
ATOM 9786 N NZ  . LYS E 4 481 ? 180.017 152.640 121.213 1.00 114.48 ? 493 LYS A NZ  1 
ATOM 9787 N N   . GLN E 4 482 ? 178.383 159.320 123.605 1.00 112.84 ? 494 GLN A N   1 
ATOM 9788 C CA  . GLN E 4 482 ? 177.889 160.009 124.789 1.00 112.84 ? 494 GLN A CA  1 
ATOM 9789 C C   . GLN E 4 482 ? 176.424 160.396 124.645 1.00 112.84 ? 494 GLN A C   1 
ATOM 9790 O O   . GLN E 4 482 ? 175.657 160.265 125.606 1.00 112.84 ? 494 GLN A O   1 
ATOM 9791 C CB  . GLN E 4 482 ? 178.734 161.254 125.067 1.00 112.84 ? 494 GLN A CB  1 
ATOM 9792 C CG  . GLN E 4 482 ? 178.338 161.999 126.329 1.00 112.84 ? 494 GLN A CG  1 
ATOM 9793 C CD  . GLN E 4 482 ? 178.081 161.067 127.497 1.00 112.84 ? 494 GLN A CD  1 
ATOM 9794 O OE1 . GLN E 4 482 ? 178.897 160.196 127.804 1.00 112.84 ? 494 GLN A OE1 1 
ATOM 9795 N NE2 . GLN E 4 482 ? 176.938 161.238 128.150 1.00 112.84 ? 494 GLN A NE2 1 
ATOM 9796 N N   . ALA E 4 483 ? 176.019 160.868 123.467 1.00 113.83 ? 495 ALA A N   1 
ATOM 9797 C CA  . ALA E 4 483 ? 174.626 161.197 123.197 1.00 113.83 ? 495 ALA A CA  1 
ATOM 9798 C C   . ALA E 4 483 ? 173.835 159.932 122.888 1.00 113.83 ? 495 ALA A C   1 
ATOM 9799 O O   . ALA E 4 483 ? 174.299 158.822 123.167 1.00 113.83 ? 495 ALA A O   1 
ATOM 9800 C CB  . ALA E 4 483 ? 174.521 162.192 122.040 1.00 113.83 ? 495 ALA A CB  1 
ATOM 9801 N N   . CYS E 4 484 ? 172.637 160.090 122.333 1.00 120.74 ? 496 CYS A N   1 
ATOM 9802 C CA  . CYS E 4 484 ? 171.811 158.950 121.946 1.00 120.74 ? 496 CYS A CA  1 
ATOM 9803 C C   . CYS E 4 484 ? 172.534 158.053 120.946 1.00 120.74 ? 496 CYS A C   1 
ATOM 9804 O O   . CYS E 4 484 ? 173.419 158.504 120.218 1.00 120.74 ? 496 CYS A O   1 
ATOM 9805 C CB  . CYS E 4 484 ? 170.485 159.425 121.349 1.00 120.74 ? 496 CYS A CB  1 
ATOM 9806 S SG  . CYS E 4 484 ? 170.501 159.581 119.547 1.00 120.74 ? 496 CYS A SG  1 
# 
