data_8TYW
# 
_entry.id   8TYW 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8TYW         pdb_00008tyw 10.2210/pdb8tyw/pdb 
WWPDB D_1000276624 ?            ?                   
EMDB  EMD-41729    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-12-04 
2 'Structure model' 1 1 2024-12-18 
3 'Structure model' 1 2 2025-01-08 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' citation        
5 3 'Structure model' citation_author 
6 3 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
3 2 'Structure model' '_citation.title'                   
4 2 'Structure model' '_citation_author.name'             
5 2 'Structure model' '_em_admin.last_update'             
6 3 'Structure model' '_citation.page_first'              
7 3 'Structure model' '_citation.page_last'               
8 3 'Structure model' '_citation_author.identifier_ORCID' 
9 3 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8TYW 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'cryo-EM structure of GPR6-Gs-Nb35 complex' 
_pdbx_database_related.db_id          EMD-41729 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              cherezov@usc.edu 
_pdbx_contact_author.name_first         Vadim 
_pdbx_contact_author.name_last          Cherezov 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5265-3914 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Barekatain, M.'   1  ? 
'Johansson, L.C.'  2  ? 
'Lam, J.H.'        3  ? 
'Sadybekov, A.V.'  4  ? 
'Han, G.W.'        5  ? 
'Popov, P.'        6  ? 
'Russo, J.'        7  ? 
'Bliesath, J.'     8  ? 
'Brice, N.'        9  ? 
'Beresford, M.'    10 ? 
'Carlson, L.'      11 ? 
'Saikatendu, K.S.' 12 ? 
'Sun, H.'          13 ? 
'Murphy, S.'       14 ? 
'Monenschein, H.'  15 ? 
'Schiffer, H.H.'   16 ? 
'Lutomski, C.'     17 ? 
'Robinson, C.V.'   18 ? 
'Liu, J.'          19 ? 
'Hua, T.'          20 ? 
'Katritch, V.'     21 ? 
'Cherezov, V.'     22 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Sci.Signal. 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1937-9145 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            17 
_citation.language                  ? 
_citation.page_first                eado8741 
_citation.page_last                 eado8741 
_citation.title                     
;Structural insights into the high basal activity and inverse agonism of the orphan receptor GPR6 implicated in Parkinson's disease.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/scisignal.ado8741 
_citation.pdbx_database_id_PubMed   39626010 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Barekatain, M.'   1  0000-0003-4178-684X 
primary 'Johansson, L.C.'  2  ?                   
primary 'Lam, J.H.'        3  0000-0002-5496-6228 
primary 'Chang, H.'        4  0000-0003-1684-8201 
primary 'Sadybekov, A.V.'  5  0000-0003-3925-983X 
primary 'Han, G.W.'        6  0000-0003-4107-835X 
primary 'Russo, J.'        7  ?                   
primary 'Bliesath, J.'     8  ?                   
primary 'Brice, N.L.'      9  ?                   
primary 'Carlton, M.B.L.'  10 ?                   
primary 'Saikatendu, K.S.' 11 0000-0001-6734-237X 
primary 'Sun, H.'          12 ?                   
primary 'Murphy, S.T.'     13 0009-0000-5404-6512 
primary 'Monenschein, H.'  14 ?                   
primary 'Schiffer, H.H.'   15 ?                   
primary 'Popov, P.'        16 ?                   
primary 'Lutomski, C.A.'   17 0000-0001-7509-103X 
primary 'Robinson, C.V.'   18 0000-0001-7829-5505 
primary 'Liu, Z.J.'        19 0000-0001-7279-2893 
primary 'Hua, T.'          20 0000-0002-6132-2068 
primary 'Katritch, V.'     21 0000-0003-3883-4505 
primary 'Cherezov, V.'     22 0000-0002-5265-3914 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'G-protein coupled receptor 6'                                         39287.512 1 ? ? ? ? 
2 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'     38534.062 1 ? ? ? ? 
3 polymer man 'Guanine nucleotide-binding protein G(s) subunit alpha isoforms short' 45683.434 1 ? 
'S54N, G226A, E268A, N271K, K274D, R280K, T284D, I285T' ? ? 
4 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'    7861.143  1 ? ? ? ? 
5 polymer man Nb35                                                                   15140.742 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
2 'Transducin beta chain 1'                       
3 'Adenylate cyclase-stimulating G alpha protein' 
4 'G gamma-I'                                     
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNPWDVLLC
VSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLL
AITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGI
MLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATY
NSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFRSRSPSEVHHHHHHHHHH
;
;MNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNPWDVLLC
VSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLL
AITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGI
MLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATY
NSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFRSRSPSEVHHHHHHHHHH
;
A ? 
2 'polypeptide(L)' no no 
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
B ? 
3 'polypeptide(L)' no no 
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKNTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQAALKLFDSIWNNKWLRDTSVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKNTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQAALKLFDSIWNNKWLRDTSVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
C ? 
4 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
5 'polypeptide(L)' no no 
;QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTLY
LQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSSHHHHHHEPEA
;
;QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTLY
LQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSSHHHHHHEPEA
;
N ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASN n 
1 3   ALA n 
1 4   SER n 
1 5   ALA n 
1 6   ALA n 
1 7   SER n 
1 8   LEU n 
1 9   ASN n 
1 10  ASP n 
1 11  SER n 
1 12  GLN n 
1 13  VAL n 
1 14  VAL n 
1 15  VAL n 
1 16  VAL n 
1 17  ALA n 
1 18  ALA n 
1 19  GLU n 
1 20  GLY n 
1 21  ALA n 
1 22  ALA n 
1 23  ALA n 
1 24  ALA n 
1 25  ALA n 
1 26  THR n 
1 27  ALA n 
1 28  ALA n 
1 29  GLY n 
1 30  GLY n 
1 31  PRO n 
1 32  ASP n 
1 33  THR n 
1 34  GLY n 
1 35  GLU n 
1 36  TRP n 
1 37  GLY n 
1 38  PRO n 
1 39  PRO n 
1 40  ALA n 
1 41  ALA n 
1 42  ALA n 
1 43  ALA n 
1 44  LEU n 
1 45  GLY n 
1 46  ALA n 
1 47  GLY n 
1 48  GLY n 
1 49  GLY n 
1 50  ALA n 
1 51  ASN n 
1 52  GLY n 
1 53  SER n 
1 54  LEU n 
1 55  GLU n 
1 56  LEU n 
1 57  SER n 
1 58  SER n 
1 59  GLN n 
1 60  LEU n 
1 61  SER n 
1 62  ALA n 
1 63  GLY n 
1 64  PRO n 
1 65  PRO n 
1 66  GLY n 
1 67  LEU n 
1 68  LEU n 
1 69  LEU n 
1 70  PRO n 
1 71  ALA n 
1 72  VAL n 
1 73  ASN n 
1 74  PRO n 
1 75  TRP n 
1 76  ASP n 
1 77  VAL n 
1 78  LEU n 
1 79  LEU n 
1 80  CYS n 
1 81  VAL n 
1 82  SER n 
1 83  GLY n 
1 84  THR n 
1 85  VAL n 
1 86  ILE n 
1 87  ALA n 
1 88  GLY n 
1 89  GLU n 
1 90  ASN n 
1 91  ALA n 
1 92  LEU n 
1 93  VAL n 
1 94  VAL n 
1 95  ALA n 
1 96  LEU n 
1 97  ILE n 
1 98  ALA n 
1 99  SER n 
1 100 THR n 
1 101 PRO n 
1 102 ALA n 
1 103 LEU n 
1 104 ARG n 
1 105 THR n 
1 106 PRO n 
1 107 MET n 
1 108 PHE n 
1 109 VAL n 
1 110 LEU n 
1 111 VAL n 
1 112 GLY n 
1 113 SER n 
1 114 LEU n 
1 115 ALA n 
1 116 THR n 
1 117 ALA n 
1 118 ASP n 
1 119 LEU n 
1 120 LEU n 
1 121 ALA n 
1 122 GLY n 
1 123 CYS n 
1 124 GLY n 
1 125 LEU n 
1 126 ILE n 
1 127 LEU n 
1 128 HIS n 
1 129 PHE n 
1 130 VAL n 
1 131 PHE n 
1 132 GLN n 
1 133 TYR n 
1 134 LEU n 
1 135 VAL n 
1 136 PRO n 
1 137 SER n 
1 138 GLU n 
1 139 THR n 
1 140 VAL n 
1 141 SER n 
1 142 LEU n 
1 143 LEU n 
1 144 THR n 
1 145 VAL n 
1 146 GLY n 
1 147 PHE n 
1 148 LEU n 
1 149 VAL n 
1 150 ALA n 
1 151 SER n 
1 152 PHE n 
1 153 ALA n 
1 154 ALA n 
1 155 SER n 
1 156 VAL n 
1 157 SER n 
1 158 SER n 
1 159 LEU n 
1 160 LEU n 
1 161 ALA n 
1 162 ILE n 
1 163 THR n 
1 164 VAL n 
1 165 ASP n 
1 166 ARG n 
1 167 TYR n 
1 168 LEU n 
1 169 SER n 
1 170 LEU n 
1 171 TYR n 
1 172 ASN n 
1 173 ALA n 
1 174 LEU n 
1 175 THR n 
1 176 TYR n 
1 177 TYR n 
1 178 SER n 
1 179 ARG n 
1 180 ARG n 
1 181 THR n 
1 182 LEU n 
1 183 LEU n 
1 184 GLY n 
1 185 VAL n 
1 186 HIS n 
1 187 LEU n 
1 188 LEU n 
1 189 LEU n 
1 190 ALA n 
1 191 ALA n 
1 192 THR n 
1 193 TRP n 
1 194 THR n 
1 195 VAL n 
1 196 SER n 
1 197 LEU n 
1 198 GLY n 
1 199 LEU n 
1 200 GLY n 
1 201 LEU n 
1 202 LEU n 
1 203 PRO n 
1 204 VAL n 
1 205 LEU n 
1 206 GLY n 
1 207 TRP n 
1 208 ASN n 
1 209 CYS n 
1 210 LEU n 
1 211 ALA n 
1 212 GLU n 
1 213 ARG n 
1 214 ALA n 
1 215 ALA n 
1 216 CYS n 
1 217 SER n 
1 218 VAL n 
1 219 VAL n 
1 220 ARG n 
1 221 PRO n 
1 222 LEU n 
1 223 ALA n 
1 224 ARG n 
1 225 SER n 
1 226 HIS n 
1 227 VAL n 
1 228 ALA n 
1 229 LEU n 
1 230 LEU n 
1 231 SER n 
1 232 ALA n 
1 233 ALA n 
1 234 PHE n 
1 235 PHE n 
1 236 MET n 
1 237 VAL n 
1 238 PHE n 
1 239 GLY n 
1 240 ILE n 
1 241 MET n 
1 242 LEU n 
1 243 HIS n 
1 244 LEU n 
1 245 TYR n 
1 246 VAL n 
1 247 ARG n 
1 248 ILE n 
1 249 CYS n 
1 250 GLN n 
1 251 VAL n 
1 252 VAL n 
1 253 TRP n 
1 254 ARG n 
1 255 HIS n 
1 256 ALA n 
1 257 HIS n 
1 258 GLN n 
1 259 ILE n 
1 260 ALA n 
1 261 LEU n 
1 262 GLN n 
1 263 GLN n 
1 264 HIS n 
1 265 CYS n 
1 266 LEU n 
1 267 ALA n 
1 268 PRO n 
1 269 PRO n 
1 270 HIS n 
1 271 LEU n 
1 272 ALA n 
1 273 ALA n 
1 274 THR n 
1 275 ARG n 
1 276 LYS n 
1 277 GLY n 
1 278 VAL n 
1 279 GLY n 
1 280 THR n 
1 281 LEU n 
1 282 ALA n 
1 283 VAL n 
1 284 VAL n 
1 285 LEU n 
1 286 GLY n 
1 287 THR n 
1 288 PHE n 
1 289 GLY n 
1 290 ALA n 
1 291 SER n 
1 292 TRP n 
1 293 LEU n 
1 294 PRO n 
1 295 PHE n 
1 296 ALA n 
1 297 ILE n 
1 298 TYR n 
1 299 CYS n 
1 300 VAL n 
1 301 VAL n 
1 302 GLY n 
1 303 SER n 
1 304 HIS n 
1 305 GLU n 
1 306 ASP n 
1 307 PRO n 
1 308 ALA n 
1 309 VAL n 
1 310 TYR n 
1 311 THR n 
1 312 TYR n 
1 313 ALA n 
1 314 THR n 
1 315 LEU n 
1 316 LEU n 
1 317 PRO n 
1 318 ALA n 
1 319 THR n 
1 320 TYR n 
1 321 ASN n 
1 322 SER n 
1 323 MET n 
1 324 ILE n 
1 325 ASN n 
1 326 PRO n 
1 327 ILE n 
1 328 ILE n 
1 329 TYR n 
1 330 ALA n 
1 331 PHE n 
1 332 ARG n 
1 333 ASN n 
1 334 GLN n 
1 335 GLU n 
1 336 ILE n 
1 337 GLN n 
1 338 ARG n 
1 339 ALA n 
1 340 LEU n 
1 341 TRP n 
1 342 LEU n 
1 343 LEU n 
1 344 LEU n 
1 345 CYS n 
1 346 GLY n 
1 347 CYS n 
1 348 PHE n 
1 349 GLN n 
1 350 SER n 
1 351 LYS n 
1 352 VAL n 
1 353 PRO n 
1 354 PHE n 
1 355 ARG n 
1 356 SER n 
1 357 ARG n 
1 358 SER n 
1 359 PRO n 
1 360 SER n 
1 361 GLU n 
1 362 VAL n 
1 363 HIS n 
1 364 HIS n 
1 365 HIS n 
1 366 HIS n 
1 367 HIS n 
1 368 HIS n 
1 369 HIS n 
1 370 HIS n 
1 371 HIS n 
1 372 HIS n 
2 1   MET n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   GLY n 
2 9   SER n 
2 10  SER n 
2 11  GLY n 
2 12  SER n 
2 13  GLU n 
2 14  LEU n 
2 15  ASP n 
2 16  GLN n 
2 17  LEU n 
2 18  ARG n 
2 19  GLN n 
2 20  GLU n 
2 21  ALA n 
2 22  GLU n 
2 23  GLN n 
2 24  LEU n 
2 25  LYS n 
2 26  ASN n 
2 27  GLN n 
2 28  ILE n 
2 29  ARG n 
2 30  ASP n 
2 31  ALA n 
2 32  ARG n 
2 33  LYS n 
2 34  ALA n 
2 35  CYS n 
2 36  ALA n 
2 37  ASP n 
2 38  ALA n 
2 39  THR n 
2 40  LEU n 
2 41  SER n 
2 42  GLN n 
2 43  ILE n 
2 44  THR n 
2 45  ASN n 
2 46  ASN n 
2 47  ILE n 
2 48  ASP n 
2 49  PRO n 
2 50  VAL n 
2 51  GLY n 
2 52  ARG n 
2 53  ILE n 
2 54  GLN n 
2 55  MET n 
2 56  ARG n 
2 57  THR n 
2 58  ARG n 
2 59  ARG n 
2 60  THR n 
2 61  LEU n 
2 62  ARG n 
2 63  GLY n 
2 64  HIS n 
2 65  LEU n 
2 66  ALA n 
2 67  LYS n 
2 68  ILE n 
2 69  TYR n 
2 70  ALA n 
2 71  MET n 
2 72  HIS n 
2 73  TRP n 
2 74  GLY n 
2 75  THR n 
2 76  ASP n 
2 77  SER n 
2 78  ARG n 
2 79  LEU n 
2 80  LEU n 
2 81  VAL n 
2 82  SER n 
2 83  ALA n 
2 84  SER n 
2 85  GLN n 
2 86  ASP n 
2 87  GLY n 
2 88  LYS n 
2 89  LEU n 
2 90  ILE n 
2 91  ILE n 
2 92  TRP n 
2 93  ASP n 
2 94  SER n 
2 95  TYR n 
2 96  THR n 
2 97  THR n 
2 98  ASN n 
2 99  LYS n 
2 100 VAL n 
2 101 HIS n 
2 102 ALA n 
2 103 ILE n 
2 104 PRO n 
2 105 LEU n 
2 106 ARG n 
2 107 SER n 
2 108 SER n 
2 109 TRP n 
2 110 VAL n 
2 111 MET n 
2 112 THR n 
2 113 CYS n 
2 114 ALA n 
2 115 TYR n 
2 116 ALA n 
2 117 PRO n 
2 118 SER n 
2 119 GLY n 
2 120 ASN n 
2 121 TYR n 
2 122 VAL n 
2 123 ALA n 
2 124 CYS n 
2 125 GLY n 
2 126 GLY n 
2 127 LEU n 
2 128 ASP n 
2 129 ASN n 
2 130 ILE n 
2 131 CYS n 
2 132 SER n 
2 133 ILE n 
2 134 TYR n 
2 135 ASN n 
2 136 LEU n 
2 137 LYS n 
2 138 THR n 
2 139 ARG n 
2 140 GLU n 
2 141 GLY n 
2 142 ASN n 
2 143 VAL n 
2 144 ARG n 
2 145 VAL n 
2 146 SER n 
2 147 ARG n 
2 148 GLU n 
2 149 LEU n 
2 150 ALA n 
2 151 GLY n 
2 152 HIS n 
2 153 THR n 
2 154 GLY n 
2 155 TYR n 
2 156 LEU n 
2 157 SER n 
2 158 CYS n 
2 159 CYS n 
2 160 ARG n 
2 161 PHE n 
2 162 LEU n 
2 163 ASP n 
2 164 ASP n 
2 165 ASN n 
2 166 GLN n 
2 167 ILE n 
2 168 VAL n 
2 169 THR n 
2 170 SER n 
2 171 SER n 
2 172 GLY n 
2 173 ASP n 
2 174 THR n 
2 175 THR n 
2 176 CYS n 
2 177 ALA n 
2 178 LEU n 
2 179 TRP n 
2 180 ASP n 
2 181 ILE n 
2 182 GLU n 
2 183 THR n 
2 184 GLY n 
2 185 GLN n 
2 186 GLN n 
2 187 THR n 
2 188 THR n 
2 189 THR n 
2 190 PHE n 
2 191 THR n 
2 192 GLY n 
2 193 HIS n 
2 194 THR n 
2 195 GLY n 
2 196 ASP n 
2 197 VAL n 
2 198 MET n 
2 199 SER n 
2 200 LEU n 
2 201 SER n 
2 202 LEU n 
2 203 ALA n 
2 204 PRO n 
2 205 ASP n 
2 206 THR n 
2 207 ARG n 
2 208 LEU n 
2 209 PHE n 
2 210 VAL n 
2 211 SER n 
2 212 GLY n 
2 213 ALA n 
2 214 CYS n 
2 215 ASP n 
2 216 ALA n 
2 217 SER n 
2 218 ALA n 
2 219 LYS n 
2 220 LEU n 
2 221 TRP n 
2 222 ASP n 
2 223 VAL n 
2 224 ARG n 
2 225 GLU n 
2 226 GLY n 
2 227 MET n 
2 228 CYS n 
2 229 ARG n 
2 230 GLN n 
2 231 THR n 
2 232 PHE n 
2 233 THR n 
2 234 GLY n 
2 235 HIS n 
2 236 GLU n 
2 237 SER n 
2 238 ASP n 
2 239 ILE n 
2 240 ASN n 
2 241 ALA n 
2 242 ILE n 
2 243 CYS n 
2 244 PHE n 
2 245 PHE n 
2 246 PRO n 
2 247 ASN n 
2 248 GLY n 
2 249 ASN n 
2 250 ALA n 
2 251 PHE n 
2 252 ALA n 
2 253 THR n 
2 254 GLY n 
2 255 SER n 
2 256 ASP n 
2 257 ASP n 
2 258 ALA n 
2 259 THR n 
2 260 CYS n 
2 261 ARG n 
2 262 LEU n 
2 263 PHE n 
2 264 ASP n 
2 265 LEU n 
2 266 ARG n 
2 267 ALA n 
2 268 ASP n 
2 269 GLN n 
2 270 GLU n 
2 271 LEU n 
2 272 MET n 
2 273 THR n 
2 274 TYR n 
2 275 SER n 
2 276 HIS n 
2 277 ASP n 
2 278 ASN n 
2 279 ILE n 
2 280 ILE n 
2 281 CYS n 
2 282 GLY n 
2 283 ILE n 
2 284 THR n 
2 285 SER n 
2 286 VAL n 
2 287 SER n 
2 288 PHE n 
2 289 SER n 
2 290 LYS n 
2 291 SER n 
2 292 GLY n 
2 293 ARG n 
2 294 LEU n 
2 295 LEU n 
2 296 LEU n 
2 297 ALA n 
2 298 GLY n 
2 299 TYR n 
2 300 ASP n 
2 301 ASP n 
2 302 PHE n 
2 303 ASN n 
2 304 CYS n 
2 305 ASN n 
2 306 VAL n 
2 307 TRP n 
2 308 ASP n 
2 309 ALA n 
2 310 LEU n 
2 311 LYS n 
2 312 ALA n 
2 313 ASP n 
2 314 ARG n 
2 315 ALA n 
2 316 GLY n 
2 317 VAL n 
2 318 LEU n 
2 319 ALA n 
2 320 GLY n 
2 321 HIS n 
2 322 ASP n 
2 323 ASN n 
2 324 ARG n 
2 325 VAL n 
2 326 SER n 
2 327 CYS n 
2 328 LEU n 
2 329 GLY n 
2 330 VAL n 
2 331 THR n 
2 332 ASP n 
2 333 ASP n 
2 334 GLY n 
2 335 MET n 
2 336 ALA n 
2 337 VAL n 
2 338 ALA n 
2 339 THR n 
2 340 GLY n 
2 341 SER n 
2 342 TRP n 
2 343 ASP n 
2 344 SER n 
2 345 PHE n 
2 346 LEU n 
2 347 LYS n 
2 348 ILE n 
2 349 TRP n 
2 350 ASN n 
3 1   MET n 
3 2   GLY n 
3 3   CYS n 
3 4   LEU n 
3 5   GLY n 
3 6   ASN n 
3 7   SER n 
3 8   LYS n 
3 9   THR n 
3 10  GLU n 
3 11  ASP n 
3 12  GLN n 
3 13  ARG n 
3 14  ASN n 
3 15  GLU n 
3 16  GLU n 
3 17  LYS n 
3 18  ALA n 
3 19  GLN n 
3 20  ARG n 
3 21  GLU n 
3 22  ALA n 
3 23  ASN n 
3 24  LYS n 
3 25  LYS n 
3 26  ILE n 
3 27  GLU n 
3 28  LYS n 
3 29  GLN n 
3 30  LEU n 
3 31  GLN n 
3 32  LYS n 
3 33  ASP n 
3 34  LYS n 
3 35  GLN n 
3 36  VAL n 
3 37  TYR n 
3 38  ARG n 
3 39  ALA n 
3 40  THR n 
3 41  HIS n 
3 42  ARG n 
3 43  LEU n 
3 44  LEU n 
3 45  LEU n 
3 46  LEU n 
3 47  GLY n 
3 48  ALA n 
3 49  GLY n 
3 50  GLU n 
3 51  SER n 
3 52  GLY n 
3 53  LYS n 
3 54  ASN n 
3 55  THR n 
3 56  ILE n 
3 57  VAL n 
3 58  LYS n 
3 59  GLN n 
3 60  MET n 
3 61  ARG n 
3 62  ILE n 
3 63  LEU n 
3 64  HIS n 
3 65  VAL n 
3 66  ASN n 
3 67  GLY n 
3 68  PHE n 
3 69  ASN n 
3 70  GLY n 
3 71  GLU n 
3 72  GLY n 
3 73  GLY n 
3 74  GLU n 
3 75  GLU n 
3 76  ASP n 
3 77  PRO n 
3 78  GLN n 
3 79  ALA n 
3 80  ALA n 
3 81  ARG n 
3 82  SER n 
3 83  ASN n 
3 84  SER n 
3 85  ASP n 
3 86  GLY n 
3 87  GLU n 
3 88  LYS n 
3 89  ALA n 
3 90  THR n 
3 91  LYS n 
3 92  VAL n 
3 93  GLN n 
3 94  ASP n 
3 95  ILE n 
3 96  LYS n 
3 97  ASN n 
3 98  ASN n 
3 99  LEU n 
3 100 LYS n 
3 101 GLU n 
3 102 ALA n 
3 103 ILE n 
3 104 GLU n 
3 105 THR n 
3 106 ILE n 
3 107 VAL n 
3 108 ALA n 
3 109 ALA n 
3 110 MET n 
3 111 SER n 
3 112 ASN n 
3 113 LEU n 
3 114 VAL n 
3 115 PRO n 
3 116 PRO n 
3 117 VAL n 
3 118 GLU n 
3 119 LEU n 
3 120 ALA n 
3 121 ASN n 
3 122 PRO n 
3 123 GLU n 
3 124 ASN n 
3 125 GLN n 
3 126 PHE n 
3 127 ARG n 
3 128 VAL n 
3 129 ASP n 
3 130 TYR n 
3 131 ILE n 
3 132 LEU n 
3 133 SER n 
3 134 VAL n 
3 135 MET n 
3 136 ASN n 
3 137 VAL n 
3 138 PRO n 
3 139 ASP n 
3 140 PHE n 
3 141 ASP n 
3 142 PHE n 
3 143 PRO n 
3 144 PRO n 
3 145 GLU n 
3 146 PHE n 
3 147 TYR n 
3 148 GLU n 
3 149 HIS n 
3 150 ALA n 
3 151 LYS n 
3 152 ALA n 
3 153 LEU n 
3 154 TRP n 
3 155 GLU n 
3 156 ASP n 
3 157 GLU n 
3 158 GLY n 
3 159 VAL n 
3 160 ARG n 
3 161 ALA n 
3 162 CYS n 
3 163 TYR n 
3 164 GLU n 
3 165 ARG n 
3 166 SER n 
3 167 ASN n 
3 168 GLU n 
3 169 TYR n 
3 170 GLN n 
3 171 LEU n 
3 172 ILE n 
3 173 ASP n 
3 174 CYS n 
3 175 ALA n 
3 176 GLN n 
3 177 TYR n 
3 178 PHE n 
3 179 LEU n 
3 180 ASP n 
3 181 LYS n 
3 182 ILE n 
3 183 ASP n 
3 184 VAL n 
3 185 ILE n 
3 186 LYS n 
3 187 GLN n 
3 188 ALA n 
3 189 ASP n 
3 190 TYR n 
3 191 VAL n 
3 192 PRO n 
3 193 SER n 
3 194 ASP n 
3 195 GLN n 
3 196 ASP n 
3 197 LEU n 
3 198 LEU n 
3 199 ARG n 
3 200 CYS n 
3 201 ARG n 
3 202 VAL n 
3 203 LEU n 
3 204 THR n 
3 205 SER n 
3 206 GLY n 
3 207 ILE n 
3 208 PHE n 
3 209 GLU n 
3 210 THR n 
3 211 LYS n 
3 212 PHE n 
3 213 GLN n 
3 214 VAL n 
3 215 ASP n 
3 216 LYS n 
3 217 VAL n 
3 218 ASN n 
3 219 PHE n 
3 220 HIS n 
3 221 MET n 
3 222 PHE n 
3 223 ASP n 
3 224 VAL n 
3 225 GLY n 
3 226 ALA n 
3 227 GLN n 
3 228 ARG n 
3 229 ASP n 
3 230 GLU n 
3 231 ARG n 
3 232 ARG n 
3 233 LYS n 
3 234 TRP n 
3 235 ILE n 
3 236 GLN n 
3 237 CYS n 
3 238 PHE n 
3 239 ASN n 
3 240 ASP n 
3 241 VAL n 
3 242 THR n 
3 243 ALA n 
3 244 ILE n 
3 245 ILE n 
3 246 PHE n 
3 247 VAL n 
3 248 VAL n 
3 249 ALA n 
3 250 SER n 
3 251 SER n 
3 252 SER n 
3 253 TYR n 
3 254 ASN n 
3 255 MET n 
3 256 VAL n 
3 257 ILE n 
3 258 ARG n 
3 259 GLU n 
3 260 ASP n 
3 261 ASN n 
3 262 GLN n 
3 263 THR n 
3 264 ASN n 
3 265 ARG n 
3 266 LEU n 
3 267 GLN n 
3 268 ALA n 
3 269 ALA n 
3 270 LEU n 
3 271 LYS n 
3 272 LEU n 
3 273 PHE n 
3 274 ASP n 
3 275 SER n 
3 276 ILE n 
3 277 TRP n 
3 278 ASN n 
3 279 ASN n 
3 280 LYS n 
3 281 TRP n 
3 282 LEU n 
3 283 ARG n 
3 284 ASP n 
3 285 THR n 
3 286 SER n 
3 287 VAL n 
3 288 ILE n 
3 289 LEU n 
3 290 PHE n 
3 291 LEU n 
3 292 ASN n 
3 293 LYS n 
3 294 GLN n 
3 295 ASP n 
3 296 LEU n 
3 297 LEU n 
3 298 ALA n 
3 299 GLU n 
3 300 LYS n 
3 301 VAL n 
3 302 LEU n 
3 303 ALA n 
3 304 GLY n 
3 305 LYS n 
3 306 SER n 
3 307 LYS n 
3 308 ILE n 
3 309 GLU n 
3 310 ASP n 
3 311 TYR n 
3 312 PHE n 
3 313 PRO n 
3 314 GLU n 
3 315 PHE n 
3 316 ALA n 
3 317 ARG n 
3 318 TYR n 
3 319 THR n 
3 320 THR n 
3 321 PRO n 
3 322 GLU n 
3 323 ASP n 
3 324 ALA n 
3 325 THR n 
3 326 PRO n 
3 327 GLU n 
3 328 PRO n 
3 329 GLY n 
3 330 GLU n 
3 331 ASP n 
3 332 PRO n 
3 333 ARG n 
3 334 VAL n 
3 335 THR n 
3 336 ARG n 
3 337 ALA n 
3 338 LYS n 
3 339 TYR n 
3 340 PHE n 
3 341 ILE n 
3 342 ARG n 
3 343 ASP n 
3 344 GLU n 
3 345 PHE n 
3 346 LEU n 
3 347 ARG n 
3 348 ILE n 
3 349 SER n 
3 350 THR n 
3 351 ALA n 
3 352 SER n 
3 353 GLY n 
3 354 ASP n 
3 355 GLY n 
3 356 ARG n 
3 357 HIS n 
3 358 TYR n 
3 359 CYS n 
3 360 TYR n 
3 361 PRO n 
3 362 HIS n 
3 363 PHE n 
3 364 THR n 
3 365 CYS n 
3 366 ALA n 
3 367 VAL n 
3 368 ASP n 
3 369 THR n 
3 370 GLU n 
3 371 ASN n 
3 372 ILE n 
3 373 ARG n 
3 374 ARG n 
3 375 VAL n 
3 376 PHE n 
3 377 ASN n 
3 378 ASP n 
3 379 CYS n 
3 380 ARG n 
3 381 ASP n 
3 382 ILE n 
3 383 ILE n 
3 384 GLN n 
3 385 ARG n 
3 386 MET n 
3 387 HIS n 
3 388 LEU n 
3 389 ARG n 
3 390 GLN n 
3 391 TYR n 
3 392 GLU n 
3 393 LEU n 
3 394 LEU n 
4 1   MET n 
4 2   ALA n 
4 3   SER n 
4 4   ASN n 
4 5   ASN n 
4 6   THR n 
4 7   ALA n 
4 8   SER n 
4 9   ILE n 
4 10  ALA n 
4 11  GLN n 
4 12  ALA n 
4 13  ARG n 
4 14  LYS n 
4 15  LEU n 
4 16  VAL n 
4 17  GLU n 
4 18  GLN n 
4 19  LEU n 
4 20  LYS n 
4 21  MET n 
4 22  GLU n 
4 23  ALA n 
4 24  ASN n 
4 25  ILE n 
4 26  ASP n 
4 27  ARG n 
4 28  ILE n 
4 29  LYS n 
4 30  VAL n 
4 31  SER n 
4 32  LYS n 
4 33  ALA n 
4 34  ALA n 
4 35  ALA n 
4 36  ASP n 
4 37  LEU n 
4 38  MET n 
4 39  ALA n 
4 40  TYR n 
4 41  CYS n 
4 42  GLU n 
4 43  ALA n 
4 44  HIS n 
4 45  ALA n 
4 46  LYS n 
4 47  GLU n 
4 48  ASP n 
4 49  PRO n 
4 50  LEU n 
4 51  LEU n 
4 52  THR n 
4 53  PRO n 
4 54  VAL n 
4 55  PRO n 
4 56  ALA n 
4 57  SER n 
4 58  GLU n 
4 59  ASN n 
4 60  PRO n 
4 61  PHE n 
4 62  ARG n 
4 63  GLU n 
4 64  LYS n 
4 65  LYS n 
4 66  PHE n 
4 67  PHE n 
4 68  CYS n 
4 69  ALA n 
4 70  ILE n 
4 71  LEU n 
5 1   GLN n 
5 2   VAL n 
5 3   GLN n 
5 4   LEU n 
5 5   GLN n 
5 6   GLU n 
5 7   SER n 
5 8   GLY n 
5 9   GLY n 
5 10  GLY n 
5 11  LEU n 
5 12  VAL n 
5 13  GLN n 
5 14  PRO n 
5 15  GLY n 
5 16  GLY n 
5 17  SER n 
5 18  LEU n 
5 19  ARG n 
5 20  LEU n 
5 21  SER n 
5 22  CYS n 
5 23  ALA n 
5 24  ALA n 
5 25  SER n 
5 26  GLY n 
5 27  PHE n 
5 28  THR n 
5 29  PHE n 
5 30  SER n 
5 31  ASN n 
5 32  TYR n 
5 33  LYS n 
5 34  MET n 
5 35  ASN n 
5 36  TRP n 
5 37  VAL n 
5 38  ARG n 
5 39  GLN n 
5 40  ALA n 
5 41  PRO n 
5 42  GLY n 
5 43  LYS n 
5 44  GLY n 
5 45  LEU n 
5 46  GLU n 
5 47  TRP n 
5 48  VAL n 
5 49  SER n 
5 50  ASP n 
5 51  ILE n 
5 52  SER n 
5 53  GLN n 
5 54  SER n 
5 55  GLY n 
5 56  ALA n 
5 57  SER n 
5 58  ILE n 
5 59  SER n 
5 60  TYR n 
5 61  THR n 
5 62  GLY n 
5 63  SER n 
5 64  VAL n 
5 65  LYS n 
5 66  GLY n 
5 67  ARG n 
5 68  PHE n 
5 69  THR n 
5 70  ILE n 
5 71  SER n 
5 72  ARG n 
5 73  ASP n 
5 74  ASN n 
5 75  ALA n 
5 76  LYS n 
5 77  ASN n 
5 78  THR n 
5 79  LEU n 
5 80  TYR n 
5 81  LEU n 
5 82  GLN n 
5 83  MET n 
5 84  ASN n 
5 85  SER n 
5 86  LEU n 
5 87  LYS n 
5 88  PRO n 
5 89  GLU n 
5 90  ASP n 
5 91  THR n 
5 92  ALA n 
5 93  VAL n 
5 94  TYR n 
5 95  TYR n 
5 96  CYS n 
5 97  ALA n 
5 98  ARG n 
5 99  CYS n 
5 100 PRO n 
5 101 ALA n 
5 102 PRO n 
5 103 PHE n 
5 104 THR n 
5 105 ARG n 
5 106 ASP n 
5 107 CYS n 
5 108 PHE n 
5 109 ASP n 
5 110 VAL n 
5 111 THR n 
5 112 SER n 
5 113 THR n 
5 114 THR n 
5 115 TYR n 
5 116 ALA n 
5 117 TYR n 
5 118 ARG n 
5 119 GLY n 
5 120 GLN n 
5 121 GLY n 
5 122 THR n 
5 123 GLN n 
5 124 VAL n 
5 125 THR n 
5 126 VAL n 
5 127 SER n 
5 128 SER n 
5 129 HIS n 
5 130 HIS n 
5 131 HIS n 
5 132 HIS n 
5 133 HIS n 
5 134 HIS n 
5 135 GLU n 
5 136 PRO n 
5 137 GLU n 
5 138 ALA n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 372 human ? GPR6               ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 350 human ? GNB1               ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 394 human ? 'GNAS, GNAS1, GSP' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 71  human ? GNG2               ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 138 ?     ? ?                  ? ? ? ? ? ? 'Lama glama'   9844 ? ? ? ? ? ? ? ? 
'Escherichia coli'      562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ASN 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   ?   ?   ?   A . n 
A 1 4   SER 4   4   ?   ?   ?   A . n 
A 1 5   ALA 5   5   ?   ?   ?   A . n 
A 1 6   ALA 6   6   ?   ?   ?   A . n 
A 1 7   SER 7   7   ?   ?   ?   A . n 
A 1 8   LEU 8   8   ?   ?   ?   A . n 
A 1 9   ASN 9   9   ?   ?   ?   A . n 
A 1 10  ASP 10  10  ?   ?   ?   A . n 
A 1 11  SER 11  11  ?   ?   ?   A . n 
A 1 12  GLN 12  12  ?   ?   ?   A . n 
A 1 13  VAL 13  13  ?   ?   ?   A . n 
A 1 14  VAL 14  14  ?   ?   ?   A . n 
A 1 15  VAL 15  15  ?   ?   ?   A . n 
A 1 16  VAL 16  16  ?   ?   ?   A . n 
A 1 17  ALA 17  17  ?   ?   ?   A . n 
A 1 18  ALA 18  18  ?   ?   ?   A . n 
A 1 19  GLU 19  19  ?   ?   ?   A . n 
A 1 20  GLY 20  20  ?   ?   ?   A . n 
A 1 21  ALA 21  21  ?   ?   ?   A . n 
A 1 22  ALA 22  22  ?   ?   ?   A . n 
A 1 23  ALA 23  23  ?   ?   ?   A . n 
A 1 24  ALA 24  24  ?   ?   ?   A . n 
A 1 25  ALA 25  25  ?   ?   ?   A . n 
A 1 26  THR 26  26  ?   ?   ?   A . n 
A 1 27  ALA 27  27  ?   ?   ?   A . n 
A 1 28  ALA 28  28  ?   ?   ?   A . n 
A 1 29  GLY 29  29  ?   ?   ?   A . n 
A 1 30  GLY 30  30  ?   ?   ?   A . n 
A 1 31  PRO 31  31  ?   ?   ?   A . n 
A 1 32  ASP 32  32  ?   ?   ?   A . n 
A 1 33  THR 33  33  ?   ?   ?   A . n 
A 1 34  GLY 34  34  ?   ?   ?   A . n 
A 1 35  GLU 35  35  ?   ?   ?   A . n 
A 1 36  TRP 36  36  ?   ?   ?   A . n 
A 1 37  GLY 37  37  ?   ?   ?   A . n 
A 1 38  PRO 38  38  ?   ?   ?   A . n 
A 1 39  PRO 39  39  ?   ?   ?   A . n 
A 1 40  ALA 40  40  ?   ?   ?   A . n 
A 1 41  ALA 41  41  ?   ?   ?   A . n 
A 1 42  ALA 42  42  ?   ?   ?   A . n 
A 1 43  ALA 43  43  ?   ?   ?   A . n 
A 1 44  LEU 44  44  ?   ?   ?   A . n 
A 1 45  GLY 45  45  ?   ?   ?   A . n 
A 1 46  ALA 46  46  ?   ?   ?   A . n 
A 1 47  GLY 47  47  ?   ?   ?   A . n 
A 1 48  GLY 48  48  ?   ?   ?   A . n 
A 1 49  GLY 49  49  ?   ?   ?   A . n 
A 1 50  ALA 50  50  ?   ?   ?   A . n 
A 1 51  ASN 51  51  ?   ?   ?   A . n 
A 1 52  GLY 52  52  ?   ?   ?   A . n 
A 1 53  SER 53  53  ?   ?   ?   A . n 
A 1 54  LEU 54  54  ?   ?   ?   A . n 
A 1 55  GLU 55  55  ?   ?   ?   A . n 
A 1 56  LEU 56  56  ?   ?   ?   A . n 
A 1 57  SER 57  57  ?   ?   ?   A . n 
A 1 58  SER 58  58  ?   ?   ?   A . n 
A 1 59  GLN 59  59  ?   ?   ?   A . n 
A 1 60  LEU 60  60  ?   ?   ?   A . n 
A 1 61  SER 61  61  ?   ?   ?   A . n 
A 1 62  ALA 62  62  ?   ?   ?   A . n 
A 1 63  GLY 63  63  ?   ?   ?   A . n 
A 1 64  PRO 64  64  ?   ?   ?   A . n 
A 1 65  PRO 65  65  ?   ?   ?   A . n 
A 1 66  GLY 66  66  ?   ?   ?   A . n 
A 1 67  LEU 67  67  ?   ?   ?   A . n 
A 1 68  LEU 68  68  ?   ?   ?   A . n 
A 1 69  LEU 69  69  ?   ?   ?   A . n 
A 1 70  PRO 70  70  ?   ?   ?   A . n 
A 1 71  ALA 71  71  ?   ?   ?   A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  ASN 73  73  73  ASN ASN A . n 
A 1 74  PRO 74  74  74  PRO PRO A . n 
A 1 75  TRP 75  75  75  TRP TRP A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  LEU 79  79  79  LEU LEU A . n 
A 1 80  CYS 80  80  80  CYS CYS A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  ILE 86  86  86  ILE ILE A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  GLY 88  88  88  GLY GLY A . n 
A 1 89  GLU 89  89  89  GLU GLU A . n 
A 1 90  ASN 90  90  90  ASN ASN A . n 
A 1 91  ALA 91  91  91  ALA ALA A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  VAL 94  94  94  VAL VAL A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  ILE 97  97  97  ILE ILE A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 PRO 101 101 101 PRO PRO A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 ARG 104 104 104 ARG ARG A . n 
A 1 105 THR 105 105 105 THR THR A . n 
A 1 106 PRO 106 106 106 PRO PRO A . n 
A 1 107 MET 107 107 107 MET MET A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 VAL 111 111 111 VAL VAL A . n 
A 1 112 GLY 112 112 112 GLY GLY A . n 
A 1 113 SER 113 113 113 SER SER A . n 
A 1 114 LEU 114 114 114 LEU LEU A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 ASP 118 118 118 ASP ASP A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 CYS 123 123 123 CYS CYS A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 LEU 125 125 125 LEU LEU A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 HIS 128 128 128 HIS HIS A . n 
A 1 129 PHE 129 129 129 PHE PHE A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 PHE 131 131 131 PHE PHE A . n 
A 1 132 GLN 132 132 132 GLN GLN A . n 
A 1 133 TYR 133 133 133 TYR TYR A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 PRO 136 136 136 PRO PRO A . n 
A 1 137 SER 137 137 137 SER SER A . n 
A 1 138 GLU 138 138 138 GLU GLU A . n 
A 1 139 THR 139 139 139 THR THR A . n 
A 1 140 VAL 140 140 140 VAL VAL A . n 
A 1 141 SER 141 141 141 SER SER A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 THR 144 144 144 THR THR A . n 
A 1 145 VAL 145 145 145 VAL VAL A . n 
A 1 146 GLY 146 146 146 GLY GLY A . n 
A 1 147 PHE 147 147 147 PHE PHE A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 VAL 149 149 149 VAL VAL A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 SER 151 151 151 SER SER A . n 
A 1 152 PHE 152 152 152 PHE PHE A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 SER 157 157 157 SER SER A . n 
A 1 158 SER 158 158 158 SER SER A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 ILE 162 162 162 ILE ILE A . n 
A 1 163 THR 163 163 163 THR THR A . n 
A 1 164 VAL 164 164 164 VAL VAL A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 ARG 166 166 166 ARG ARG A . n 
A 1 167 TYR 167 167 167 TYR TYR A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 SER 169 169 169 SER SER A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 TYR 171 171 171 TYR TYR A . n 
A 1 172 ASN 172 172 172 ASN ASN A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 LEU 174 174 174 LEU LEU A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 TYR 176 176 176 TYR TYR A . n 
A 1 177 TYR 177 177 177 TYR TYR A . n 
A 1 178 SER 178 178 178 SER SER A . n 
A 1 179 ARG 179 179 179 ARG ARG A . n 
A 1 180 ARG 180 180 180 ARG ARG A . n 
A 1 181 THR 181 181 181 THR THR A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 LEU 183 183 183 LEU LEU A . n 
A 1 184 GLY 184 184 184 GLY GLY A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 HIS 186 186 186 HIS HIS A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 LEU 188 188 188 LEU LEU A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 TRP 193 193 193 TRP TRP A . n 
A 1 194 THR 194 194 194 THR THR A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 SER 196 196 196 SER SER A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 GLY 198 198 198 GLY GLY A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 GLY 200 200 200 GLY GLY A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 LEU 202 202 202 LEU LEU A . n 
A 1 203 PRO 203 203 203 PRO PRO A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 TRP 207 207 207 TRP TRP A . n 
A 1 208 ASN 208 208 208 ASN ASN A . n 
A 1 209 CYS 209 209 209 CYS CYS A . n 
A 1 210 LEU 210 210 210 LEU LEU A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 GLU 212 212 212 GLU GLU A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 ALA 215 215 215 ALA ALA A . n 
A 1 216 CYS 216 216 216 CYS CYS A . n 
A 1 217 SER 217 217 217 SER SER A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 ARG 220 220 220 ARG ARG A . n 
A 1 221 PRO 221 221 221 PRO PRO A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 ALA 223 223 223 ALA ALA A . n 
A 1 224 ARG 224 224 224 ARG ARG A . n 
A 1 225 SER 225 225 225 SER SER A . n 
A 1 226 HIS 226 226 226 HIS HIS A . n 
A 1 227 VAL 227 227 227 VAL VAL A . n 
A 1 228 ALA 228 228 228 ALA ALA A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 SER 231 231 231 SER SER A . n 
A 1 232 ALA 232 232 232 ALA ALA A . n 
A 1 233 ALA 233 233 233 ALA ALA A . n 
A 1 234 PHE 234 234 234 PHE PHE A . n 
A 1 235 PHE 235 235 235 PHE PHE A . n 
A 1 236 MET 236 236 236 MET MET A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 PHE 238 238 238 PHE PHE A . n 
A 1 239 GLY 239 239 239 GLY GLY A . n 
A 1 240 ILE 240 240 240 ILE ILE A . n 
A 1 241 MET 241 241 241 MET MET A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 HIS 243 243 243 HIS HIS A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 TYR 245 245 245 TYR TYR A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 ARG 247 247 247 ARG ARG A . n 
A 1 248 ILE 248 248 248 ILE ILE A . n 
A 1 249 CYS 249 249 249 CYS CYS A . n 
A 1 250 GLN 250 250 250 GLN GLN A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 TRP 253 253 253 TRP TRP A . n 
A 1 254 ARG 254 254 254 ARG ARG A . n 
A 1 255 HIS 255 255 255 HIS HIS A . n 
A 1 256 ALA 256 256 256 ALA ALA A . n 
A 1 257 HIS 257 257 257 HIS HIS A . n 
A 1 258 GLN 258 258 258 GLN GLN A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 GLN 262 262 262 GLN GLN A . n 
A 1 263 GLN 263 263 263 GLN GLN A . n 
A 1 264 HIS 264 264 264 HIS HIS A . n 
A 1 265 CYS 265 265 ?   ?   ?   A . n 
A 1 266 LEU 266 266 ?   ?   ?   A . n 
A 1 267 ALA 267 267 ?   ?   ?   A . n 
A 1 268 PRO 268 268 ?   ?   ?   A . n 
A 1 269 PRO 269 269 ?   ?   ?   A . n 
A 1 270 HIS 270 270 ?   ?   ?   A . n 
A 1 271 LEU 271 271 ?   ?   ?   A . n 
A 1 272 ALA 272 272 ?   ?   ?   A . n 
A 1 273 ALA 273 273 ?   ?   ?   A . n 
A 1 274 THR 274 274 274 THR THR A . n 
A 1 275 ARG 275 275 275 ARG ARG A . n 
A 1 276 LYS 276 276 276 LYS LYS A . n 
A 1 277 GLY 277 277 277 GLY GLY A . n 
A 1 278 VAL 278 278 278 VAL VAL A . n 
A 1 279 GLY 279 279 279 GLY GLY A . n 
A 1 280 THR 280 280 280 THR THR A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 VAL 283 283 283 VAL VAL A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 GLY 286 286 286 GLY GLY A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 PHE 288 288 288 PHE PHE A . n 
A 1 289 GLY 289 289 289 GLY GLY A . n 
A 1 290 ALA 290 290 290 ALA ALA A . n 
A 1 291 SER 291 291 291 SER SER A . n 
A 1 292 TRP 292 292 292 TRP TRP A . n 
A 1 293 LEU 293 293 293 LEU LEU A . n 
A 1 294 PRO 294 294 294 PRO PRO A . n 
A 1 295 PHE 295 295 295 PHE PHE A . n 
A 1 296 ALA 296 296 296 ALA ALA A . n 
A 1 297 ILE 297 297 297 ILE ILE A . n 
A 1 298 TYR 298 298 298 TYR TYR A . n 
A 1 299 CYS 299 299 299 CYS CYS A . n 
A 1 300 VAL 300 300 300 VAL VAL A . n 
A 1 301 VAL 301 301 301 VAL VAL A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 SER 303 303 303 SER SER A . n 
A 1 304 HIS 304 304 304 HIS HIS A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 ASP 306 306 306 ASP ASP A . n 
A 1 307 PRO 307 307 307 PRO PRO A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 VAL 309 309 309 VAL VAL A . n 
A 1 310 TYR 310 310 310 TYR TYR A . n 
A 1 311 THR 311 311 311 THR THR A . n 
A 1 312 TYR 312 312 312 TYR TYR A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 THR 314 314 314 THR THR A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 LEU 316 316 316 LEU LEU A . n 
A 1 317 PRO 317 317 317 PRO PRO A . n 
A 1 318 ALA 318 318 318 ALA ALA A . n 
A 1 319 THR 319 319 319 THR THR A . n 
A 1 320 TYR 320 320 320 TYR TYR A . n 
A 1 321 ASN 321 321 321 ASN ASN A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 MET 323 323 323 MET MET A . n 
A 1 324 ILE 324 324 324 ILE ILE A . n 
A 1 325 ASN 325 325 325 ASN ASN A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 ILE 328 328 328 ILE ILE A . n 
A 1 329 TYR 329 329 329 TYR TYR A . n 
A 1 330 ALA 330 330 330 ALA ALA A . n 
A 1 331 PHE 331 331 331 PHE PHE A . n 
A 1 332 ARG 332 332 332 ARG ARG A . n 
A 1 333 ASN 333 333 333 ASN ASN A . n 
A 1 334 GLN 334 334 334 GLN GLN A . n 
A 1 335 GLU 335 335 335 GLU GLU A . n 
A 1 336 ILE 336 336 336 ILE ILE A . n 
A 1 337 GLN 337 337 337 GLN GLN A . n 
A 1 338 ARG 338 338 338 ARG ARG A . n 
A 1 339 ALA 339 339 339 ALA ALA A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 TRP 341 341 341 TRP TRP A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 LEU 343 343 343 LEU LEU A . n 
A 1 344 LEU 344 344 344 LEU LEU A . n 
A 1 345 CYS 345 345 ?   ?   ?   A . n 
A 1 346 GLY 346 346 ?   ?   ?   A . n 
A 1 347 CYS 347 347 ?   ?   ?   A . n 
A 1 348 PHE 348 348 ?   ?   ?   A . n 
A 1 349 GLN 349 349 ?   ?   ?   A . n 
A 1 350 SER 350 350 ?   ?   ?   A . n 
A 1 351 LYS 351 351 ?   ?   ?   A . n 
A 1 352 VAL 352 352 ?   ?   ?   A . n 
A 1 353 PRO 353 353 ?   ?   ?   A . n 
A 1 354 PHE 354 354 ?   ?   ?   A . n 
A 1 355 ARG 355 355 ?   ?   ?   A . n 
A 1 356 SER 356 356 ?   ?   ?   A . n 
A 1 357 ARG 357 357 ?   ?   ?   A . n 
A 1 358 SER 358 358 ?   ?   ?   A . n 
A 1 359 PRO 359 359 ?   ?   ?   A . n 
A 1 360 SER 360 360 ?   ?   ?   A . n 
A 1 361 GLU 361 361 ?   ?   ?   A . n 
A 1 362 VAL 362 362 ?   ?   ?   A . n 
A 1 363 HIS 363 363 ?   ?   ?   A . n 
A 1 364 HIS 364 364 ?   ?   ?   A . n 
A 1 365 HIS 365 365 ?   ?   ?   A . n 
A 1 366 HIS 366 366 ?   ?   ?   A . n 
A 1 367 HIS 367 367 ?   ?   ?   A . n 
A 1 368 HIS 368 368 ?   ?   ?   A . n 
A 1 369 HIS 369 369 ?   ?   ?   A . n 
A 1 370 HIS 370 370 ?   ?   ?   A . n 
A 1 371 HIS 371 371 ?   ?   ?   A . n 
A 1 372 HIS 372 372 ?   ?   ?   A . n 
B 2 1   MET 1   -9  ?   ?   ?   B . n 
B 2 2   HIS 2   -8  ?   ?   ?   B . n 
B 2 3   HIS 3   -7  ?   ?   ?   B . n 
B 2 4   HIS 4   -6  ?   ?   ?   B . n 
B 2 5   HIS 5   -5  ?   ?   ?   B . n 
B 2 6   HIS 6   -4  ?   ?   ?   B . n 
B 2 7   HIS 7   -3  ?   ?   ?   B . n 
B 2 8   GLY 8   -2  ?   ?   ?   B . n 
B 2 9   SER 9   -1  ?   ?   ?   B . n 
B 2 10  SER 10  0   ?   ?   ?   B . n 
B 2 11  GLY 11  1   ?   ?   ?   B . n 
B 2 12  SER 12  2   2   SER SER B . n 
B 2 13  GLU 13  3   3   GLU GLU B . n 
B 2 14  LEU 14  4   4   LEU LEU B . n 
B 2 15  ASP 15  5   5   ASP ASP B . n 
B 2 16  GLN 16  6   6   GLN GLN B . n 
B 2 17  LEU 17  7   7   LEU LEU B . n 
B 2 18  ARG 18  8   8   ARG ARG B . n 
B 2 19  GLN 19  9   9   GLN GLN B . n 
B 2 20  GLU 20  10  10  GLU GLU B . n 
B 2 21  ALA 21  11  11  ALA ALA B . n 
B 2 22  GLU 22  12  12  GLU GLU B . n 
B 2 23  GLN 23  13  13  GLN GLN B . n 
B 2 24  LEU 24  14  14  LEU LEU B . n 
B 2 25  LYS 25  15  15  LYS LYS B . n 
B 2 26  ASN 26  16  16  ASN ASN B . n 
B 2 27  GLN 27  17  17  GLN GLN B . n 
B 2 28  ILE 28  18  18  ILE ILE B . n 
B 2 29  ARG 29  19  19  ARG ARG B . n 
B 2 30  ASP 30  20  20  ASP ASP B . n 
B 2 31  ALA 31  21  21  ALA ALA B . n 
B 2 32  ARG 32  22  22  ARG ARG B . n 
B 2 33  LYS 33  23  23  LYS LYS B . n 
B 2 34  ALA 34  24  24  ALA ALA B . n 
B 2 35  CYS 35  25  25  CYS CYS B . n 
B 2 36  ALA 36  26  26  ALA ALA B . n 
B 2 37  ASP 37  27  27  ASP ASP B . n 
B 2 38  ALA 38  28  28  ALA ALA B . n 
B 2 39  THR 39  29  29  THR THR B . n 
B 2 40  LEU 40  30  30  LEU LEU B . n 
B 2 41  SER 41  31  31  SER SER B . n 
B 2 42  GLN 42  32  32  GLN GLN B . n 
B 2 43  ILE 43  33  33  ILE ILE B . n 
B 2 44  THR 44  34  34  THR THR B . n 
B 2 45  ASN 45  35  35  ASN ASN B . n 
B 2 46  ASN 46  36  36  ASN ASN B . n 
B 2 47  ILE 47  37  37  ILE ILE B . n 
B 2 48  ASP 48  38  38  ASP ASP B . n 
B 2 49  PRO 49  39  39  PRO PRO B . n 
B 2 50  VAL 50  40  40  VAL VAL B . n 
B 2 51  GLY 51  41  41  GLY GLY B . n 
B 2 52  ARG 52  42  42  ARG ARG B . n 
B 2 53  ILE 53  43  43  ILE ILE B . n 
B 2 54  GLN 54  44  44  GLN GLN B . n 
B 2 55  MET 55  45  45  MET MET B . n 
B 2 56  ARG 56  46  46  ARG ARG B . n 
B 2 57  THR 57  47  47  THR THR B . n 
B 2 58  ARG 58  48  48  ARG ARG B . n 
B 2 59  ARG 59  49  49  ARG ARG B . n 
B 2 60  THR 60  50  50  THR THR B . n 
B 2 61  LEU 61  51  51  LEU LEU B . n 
B 2 62  ARG 62  52  52  ARG ARG B . n 
B 2 63  GLY 63  53  53  GLY GLY B . n 
B 2 64  HIS 64  54  54  HIS HIS B . n 
B 2 65  LEU 65  55  55  LEU LEU B . n 
B 2 66  ALA 66  56  56  ALA ALA B . n 
B 2 67  LYS 67  57  57  LYS LYS B . n 
B 2 68  ILE 68  58  58  ILE ILE B . n 
B 2 69  TYR 69  59  59  TYR TYR B . n 
B 2 70  ALA 70  60  60  ALA ALA B . n 
B 2 71  MET 71  61  61  MET MET B . n 
B 2 72  HIS 72  62  62  HIS HIS B . n 
B 2 73  TRP 73  63  63  TRP TRP B . n 
B 2 74  GLY 74  64  64  GLY GLY B . n 
B 2 75  THR 75  65  65  THR THR B . n 
B 2 76  ASP 76  66  66  ASP ASP B . n 
B 2 77  SER 77  67  67  SER SER B . n 
B 2 78  ARG 78  68  68  ARG ARG B . n 
B 2 79  LEU 79  69  69  LEU LEU B . n 
B 2 80  LEU 80  70  70  LEU LEU B . n 
B 2 81  VAL 81  71  71  VAL VAL B . n 
B 2 82  SER 82  72  72  SER SER B . n 
B 2 83  ALA 83  73  73  ALA ALA B . n 
B 2 84  SER 84  74  74  SER SER B . n 
B 2 85  GLN 85  75  75  GLN GLN B . n 
B 2 86  ASP 86  76  76  ASP ASP B . n 
B 2 87  GLY 87  77  77  GLY GLY B . n 
B 2 88  LYS 88  78  78  LYS LYS B . n 
B 2 89  LEU 89  79  79  LEU LEU B . n 
B 2 90  ILE 90  80  80  ILE ILE B . n 
B 2 91  ILE 91  81  81  ILE ILE B . n 
B 2 92  TRP 92  82  82  TRP TRP B . n 
B 2 93  ASP 93  83  83  ASP ASP B . n 
B 2 94  SER 94  84  84  SER SER B . n 
B 2 95  TYR 95  85  85  TYR TYR B . n 
B 2 96  THR 96  86  86  THR THR B . n 
B 2 97  THR 97  87  87  THR THR B . n 
B 2 98  ASN 98  88  88  ASN ASN B . n 
B 2 99  LYS 99  89  89  LYS LYS B . n 
B 2 100 VAL 100 90  90  VAL VAL B . n 
B 2 101 HIS 101 91  91  HIS HIS B . n 
B 2 102 ALA 102 92  92  ALA ALA B . n 
B 2 103 ILE 103 93  93  ILE ILE B . n 
B 2 104 PRO 104 94  94  PRO PRO B . n 
B 2 105 LEU 105 95  95  LEU LEU B . n 
B 2 106 ARG 106 96  96  ARG ARG B . n 
B 2 107 SER 107 97  97  SER SER B . n 
B 2 108 SER 108 98  98  SER SER B . n 
B 2 109 TRP 109 99  99  TRP TRP B . n 
B 2 110 VAL 110 100 100 VAL VAL B . n 
B 2 111 MET 111 101 101 MET MET B . n 
B 2 112 THR 112 102 102 THR THR B . n 
B 2 113 CYS 113 103 103 CYS CYS B . n 
B 2 114 ALA 114 104 104 ALA ALA B . n 
B 2 115 TYR 115 105 105 TYR TYR B . n 
B 2 116 ALA 116 106 106 ALA ALA B . n 
B 2 117 PRO 117 107 107 PRO PRO B . n 
B 2 118 SER 118 108 108 SER SER B . n 
B 2 119 GLY 119 109 109 GLY GLY B . n 
B 2 120 ASN 120 110 110 ASN ASN B . n 
B 2 121 TYR 121 111 111 TYR TYR B . n 
B 2 122 VAL 122 112 112 VAL VAL B . n 
B 2 123 ALA 123 113 113 ALA ALA B . n 
B 2 124 CYS 124 114 114 CYS CYS B . n 
B 2 125 GLY 125 115 115 GLY GLY B . n 
B 2 126 GLY 126 116 116 GLY GLY B . n 
B 2 127 LEU 127 117 117 LEU LEU B . n 
B 2 128 ASP 128 118 118 ASP ASP B . n 
B 2 129 ASN 129 119 119 ASN ASN B . n 
B 2 130 ILE 130 120 120 ILE ILE B . n 
B 2 131 CYS 131 121 121 CYS CYS B . n 
B 2 132 SER 132 122 122 SER SER B . n 
B 2 133 ILE 133 123 123 ILE ILE B . n 
B 2 134 TYR 134 124 124 TYR TYR B . n 
B 2 135 ASN 135 125 125 ASN ASN B . n 
B 2 136 LEU 136 126 126 LEU LEU B . n 
B 2 137 LYS 137 127 127 LYS LYS B . n 
B 2 138 THR 138 128 128 THR THR B . n 
B 2 139 ARG 139 129 129 ARG ARG B . n 
B 2 140 GLU 140 130 130 GLU GLU B . n 
B 2 141 GLY 141 131 131 GLY GLY B . n 
B 2 142 ASN 142 132 132 ASN ASN B . n 
B 2 143 VAL 143 133 133 VAL VAL B . n 
B 2 144 ARG 144 134 134 ARG ARG B . n 
B 2 145 VAL 145 135 135 VAL VAL B . n 
B 2 146 SER 146 136 136 SER SER B . n 
B 2 147 ARG 147 137 137 ARG ARG B . n 
B 2 148 GLU 148 138 138 GLU GLU B . n 
B 2 149 LEU 149 139 139 LEU LEU B . n 
B 2 150 ALA 150 140 140 ALA ALA B . n 
B 2 151 GLY 151 141 141 GLY GLY B . n 
B 2 152 HIS 152 142 142 HIS HIS B . n 
B 2 153 THR 153 143 143 THR THR B . n 
B 2 154 GLY 154 144 144 GLY GLY B . n 
B 2 155 TYR 155 145 145 TYR TYR B . n 
B 2 156 LEU 156 146 146 LEU LEU B . n 
B 2 157 SER 157 147 147 SER SER B . n 
B 2 158 CYS 158 148 148 CYS CYS B . n 
B 2 159 CYS 159 149 149 CYS CYS B . n 
B 2 160 ARG 160 150 150 ARG ARG B . n 
B 2 161 PHE 161 151 151 PHE PHE B . n 
B 2 162 LEU 162 152 152 LEU LEU B . n 
B 2 163 ASP 163 153 153 ASP ASP B . n 
B 2 164 ASP 164 154 154 ASP ASP B . n 
B 2 165 ASN 165 155 155 ASN ASN B . n 
B 2 166 GLN 166 156 156 GLN GLN B . n 
B 2 167 ILE 167 157 157 ILE ILE B . n 
B 2 168 VAL 168 158 158 VAL VAL B . n 
B 2 169 THR 169 159 159 THR THR B . n 
B 2 170 SER 170 160 160 SER SER B . n 
B 2 171 SER 171 161 161 SER SER B . n 
B 2 172 GLY 172 162 162 GLY GLY B . n 
B 2 173 ASP 173 163 163 ASP ASP B . n 
B 2 174 THR 174 164 164 THR THR B . n 
B 2 175 THR 175 165 165 THR THR B . n 
B 2 176 CYS 176 166 166 CYS CYS B . n 
B 2 177 ALA 177 167 167 ALA ALA B . n 
B 2 178 LEU 178 168 168 LEU LEU B . n 
B 2 179 TRP 179 169 169 TRP TRP B . n 
B 2 180 ASP 180 170 170 ASP ASP B . n 
B 2 181 ILE 181 171 171 ILE ILE B . n 
B 2 182 GLU 182 172 172 GLU GLU B . n 
B 2 183 THR 183 173 173 THR THR B . n 
B 2 184 GLY 184 174 174 GLY GLY B . n 
B 2 185 GLN 185 175 175 GLN GLN B . n 
B 2 186 GLN 186 176 176 GLN GLN B . n 
B 2 187 THR 187 177 177 THR THR B . n 
B 2 188 THR 188 178 178 THR THR B . n 
B 2 189 THR 189 179 179 THR THR B . n 
B 2 190 PHE 190 180 180 PHE PHE B . n 
B 2 191 THR 191 181 181 THR THR B . n 
B 2 192 GLY 192 182 182 GLY GLY B . n 
B 2 193 HIS 193 183 183 HIS HIS B . n 
B 2 194 THR 194 184 184 THR THR B . n 
B 2 195 GLY 195 185 185 GLY GLY B . n 
B 2 196 ASP 196 186 186 ASP ASP B . n 
B 2 197 VAL 197 187 187 VAL VAL B . n 
B 2 198 MET 198 188 188 MET MET B . n 
B 2 199 SER 199 189 189 SER SER B . n 
B 2 200 LEU 200 190 190 LEU LEU B . n 
B 2 201 SER 201 191 191 SER SER B . n 
B 2 202 LEU 202 192 192 LEU LEU B . n 
B 2 203 ALA 203 193 193 ALA ALA B . n 
B 2 204 PRO 204 194 194 PRO PRO B . n 
B 2 205 ASP 205 195 195 ASP ASP B . n 
B 2 206 THR 206 196 196 THR THR B . n 
B 2 207 ARG 207 197 197 ARG ARG B . n 
B 2 208 LEU 208 198 198 LEU LEU B . n 
B 2 209 PHE 209 199 199 PHE PHE B . n 
B 2 210 VAL 210 200 200 VAL VAL B . n 
B 2 211 SER 211 201 201 SER SER B . n 
B 2 212 GLY 212 202 202 GLY GLY B . n 
B 2 213 ALA 213 203 203 ALA ALA B . n 
B 2 214 CYS 214 204 204 CYS CYS B . n 
B 2 215 ASP 215 205 205 ASP ASP B . n 
B 2 216 ALA 216 206 206 ALA ALA B . n 
B 2 217 SER 217 207 207 SER SER B . n 
B 2 218 ALA 218 208 208 ALA ALA B . n 
B 2 219 LYS 219 209 209 LYS LYS B . n 
B 2 220 LEU 220 210 210 LEU LEU B . n 
B 2 221 TRP 221 211 211 TRP TRP B . n 
B 2 222 ASP 222 212 212 ASP ASP B . n 
B 2 223 VAL 223 213 213 VAL VAL B . n 
B 2 224 ARG 224 214 214 ARG ARG B . n 
B 2 225 GLU 225 215 215 GLU GLU B . n 
B 2 226 GLY 226 216 216 GLY GLY B . n 
B 2 227 MET 227 217 217 MET MET B . n 
B 2 228 CYS 228 218 218 CYS CYS B . n 
B 2 229 ARG 229 219 219 ARG ARG B . n 
B 2 230 GLN 230 220 220 GLN GLN B . n 
B 2 231 THR 231 221 221 THR THR B . n 
B 2 232 PHE 232 222 222 PHE PHE B . n 
B 2 233 THR 233 223 223 THR THR B . n 
B 2 234 GLY 234 224 224 GLY GLY B . n 
B 2 235 HIS 235 225 225 HIS HIS B . n 
B 2 236 GLU 236 226 226 GLU GLU B . n 
B 2 237 SER 237 227 227 SER SER B . n 
B 2 238 ASP 238 228 228 ASP ASP B . n 
B 2 239 ILE 239 229 229 ILE ILE B . n 
B 2 240 ASN 240 230 230 ASN ASN B . n 
B 2 241 ALA 241 231 231 ALA ALA B . n 
B 2 242 ILE 242 232 232 ILE ILE B . n 
B 2 243 CYS 243 233 233 CYS CYS B . n 
B 2 244 PHE 244 234 234 PHE PHE B . n 
B 2 245 PHE 245 235 235 PHE PHE B . n 
B 2 246 PRO 246 236 236 PRO PRO B . n 
B 2 247 ASN 247 237 237 ASN ASN B . n 
B 2 248 GLY 248 238 238 GLY GLY B . n 
B 2 249 ASN 249 239 239 ASN ASN B . n 
B 2 250 ALA 250 240 240 ALA ALA B . n 
B 2 251 PHE 251 241 241 PHE PHE B . n 
B 2 252 ALA 252 242 242 ALA ALA B . n 
B 2 253 THR 253 243 243 THR THR B . n 
B 2 254 GLY 254 244 244 GLY GLY B . n 
B 2 255 SER 255 245 245 SER SER B . n 
B 2 256 ASP 256 246 246 ASP ASP B . n 
B 2 257 ASP 257 247 247 ASP ASP B . n 
B 2 258 ALA 258 248 248 ALA ALA B . n 
B 2 259 THR 259 249 249 THR THR B . n 
B 2 260 CYS 260 250 250 CYS CYS B . n 
B 2 261 ARG 261 251 251 ARG ARG B . n 
B 2 262 LEU 262 252 252 LEU LEU B . n 
B 2 263 PHE 263 253 253 PHE PHE B . n 
B 2 264 ASP 264 254 254 ASP ASP B . n 
B 2 265 LEU 265 255 255 LEU LEU B . n 
B 2 266 ARG 266 256 256 ARG ARG B . n 
B 2 267 ALA 267 257 257 ALA ALA B . n 
B 2 268 ASP 268 258 258 ASP ASP B . n 
B 2 269 GLN 269 259 259 GLN GLN B . n 
B 2 270 GLU 270 260 260 GLU GLU B . n 
B 2 271 LEU 271 261 261 LEU LEU B . n 
B 2 272 MET 272 262 262 MET MET B . n 
B 2 273 THR 273 263 263 THR THR B . n 
B 2 274 TYR 274 264 264 TYR TYR B . n 
B 2 275 SER 275 265 265 SER SER B . n 
B 2 276 HIS 276 266 266 HIS HIS B . n 
B 2 277 ASP 277 267 267 ASP ASP B . n 
B 2 278 ASN 278 268 268 ASN ASN B . n 
B 2 279 ILE 279 269 269 ILE ILE B . n 
B 2 280 ILE 280 270 270 ILE ILE B . n 
B 2 281 CYS 281 271 271 CYS CYS B . n 
B 2 282 GLY 282 272 272 GLY GLY B . n 
B 2 283 ILE 283 273 273 ILE ILE B . n 
B 2 284 THR 284 274 274 THR THR B . n 
B 2 285 SER 285 275 275 SER SER B . n 
B 2 286 VAL 286 276 276 VAL VAL B . n 
B 2 287 SER 287 277 277 SER SER B . n 
B 2 288 PHE 288 278 278 PHE PHE B . n 
B 2 289 SER 289 279 279 SER SER B . n 
B 2 290 LYS 290 280 280 LYS LYS B . n 
B 2 291 SER 291 281 281 SER SER B . n 
B 2 292 GLY 292 282 282 GLY GLY B . n 
B 2 293 ARG 293 283 283 ARG ARG B . n 
B 2 294 LEU 294 284 284 LEU LEU B . n 
B 2 295 LEU 295 285 285 LEU LEU B . n 
B 2 296 LEU 296 286 286 LEU LEU B . n 
B 2 297 ALA 297 287 287 ALA ALA B . n 
B 2 298 GLY 298 288 288 GLY GLY B . n 
B 2 299 TYR 299 289 289 TYR TYR B . n 
B 2 300 ASP 300 290 290 ASP ASP B . n 
B 2 301 ASP 301 291 291 ASP ASP B . n 
B 2 302 PHE 302 292 292 PHE PHE B . n 
B 2 303 ASN 303 293 293 ASN ASN B . n 
B 2 304 CYS 304 294 294 CYS CYS B . n 
B 2 305 ASN 305 295 295 ASN ASN B . n 
B 2 306 VAL 306 296 296 VAL VAL B . n 
B 2 307 TRP 307 297 297 TRP TRP B . n 
B 2 308 ASP 308 298 298 ASP ASP B . n 
B 2 309 ALA 309 299 299 ALA ALA B . n 
B 2 310 LEU 310 300 300 LEU LEU B . n 
B 2 311 LYS 311 301 301 LYS LYS B . n 
B 2 312 ALA 312 302 302 ALA ALA B . n 
B 2 313 ASP 313 303 303 ASP ASP B . n 
B 2 314 ARG 314 304 304 ARG ARG B . n 
B 2 315 ALA 315 305 305 ALA ALA B . n 
B 2 316 GLY 316 306 306 GLY GLY B . n 
B 2 317 VAL 317 307 307 VAL VAL B . n 
B 2 318 LEU 318 308 308 LEU LEU B . n 
B 2 319 ALA 319 309 309 ALA ALA B . n 
B 2 320 GLY 320 310 310 GLY GLY B . n 
B 2 321 HIS 321 311 311 HIS HIS B . n 
B 2 322 ASP 322 312 312 ASP ASP B . n 
B 2 323 ASN 323 313 313 ASN ASN B . n 
B 2 324 ARG 324 314 314 ARG ARG B . n 
B 2 325 VAL 325 315 315 VAL VAL B . n 
B 2 326 SER 326 316 316 SER SER B . n 
B 2 327 CYS 327 317 317 CYS CYS B . n 
B 2 328 LEU 328 318 318 LEU LEU B . n 
B 2 329 GLY 329 319 319 GLY GLY B . n 
B 2 330 VAL 330 320 320 VAL VAL B . n 
B 2 331 THR 331 321 321 THR THR B . n 
B 2 332 ASP 332 322 322 ASP ASP B . n 
B 2 333 ASP 333 323 323 ASP ASP B . n 
B 2 334 GLY 334 324 324 GLY GLY B . n 
B 2 335 MET 335 325 325 MET MET B . n 
B 2 336 ALA 336 326 326 ALA ALA B . n 
B 2 337 VAL 337 327 327 VAL VAL B . n 
B 2 338 ALA 338 328 328 ALA ALA B . n 
B 2 339 THR 339 329 329 THR THR B . n 
B 2 340 GLY 340 330 330 GLY GLY B . n 
B 2 341 SER 341 331 331 SER SER B . n 
B 2 342 TRP 342 332 332 TRP TRP B . n 
B 2 343 ASP 343 333 333 ASP ASP B . n 
B 2 344 SER 344 334 334 SER SER B . n 
B 2 345 PHE 345 335 335 PHE PHE B . n 
B 2 346 LEU 346 336 336 LEU LEU B . n 
B 2 347 LYS 347 337 337 LYS LYS B . n 
B 2 348 ILE 348 338 338 ILE ILE B . n 
B 2 349 TRP 349 339 339 TRP TRP B . n 
B 2 350 ASN 350 340 340 ASN ASN B . n 
C 3 1   MET 1   1   ?   ?   ?   C . n 
C 3 2   GLY 2   2   ?   ?   ?   C . n 
C 3 3   CYS 3   3   ?   ?   ?   C . n 
C 3 4   LEU 4   4   ?   ?   ?   C . n 
C 3 5   GLY 5   5   ?   ?   ?   C . n 
C 3 6   ASN 6   6   ?   ?   ?   C . n 
C 3 7   SER 7   7   ?   ?   ?   C . n 
C 3 8   LYS 8   8   8   LYS LYS C . n 
C 3 9   THR 9   9   9   THR THR C . n 
C 3 10  GLU 10  10  10  GLU GLU C . n 
C 3 11  ASP 11  11  11  ASP ASP C . n 
C 3 12  GLN 12  12  12  GLN GLN C . n 
C 3 13  ARG 13  13  13  ARG ARG C . n 
C 3 14  ASN 14  14  14  ASN ASN C . n 
C 3 15  GLU 15  15  15  GLU GLU C . n 
C 3 16  GLU 16  16  16  GLU GLU C . n 
C 3 17  LYS 17  17  17  LYS LYS C . n 
C 3 18  ALA 18  18  18  ALA ALA C . n 
C 3 19  GLN 19  19  19  GLN GLN C . n 
C 3 20  ARG 20  20  20  ARG ARG C . n 
C 3 21  GLU 21  21  21  GLU GLU C . n 
C 3 22  ALA 22  22  22  ALA ALA C . n 
C 3 23  ASN 23  23  23  ASN ASN C . n 
C 3 24  LYS 24  24  24  LYS LYS C . n 
C 3 25  LYS 25  25  25  LYS LYS C . n 
C 3 26  ILE 26  26  26  ILE ILE C . n 
C 3 27  GLU 27  27  27  GLU GLU C . n 
C 3 28  LYS 28  28  28  LYS LYS C . n 
C 3 29  GLN 29  29  29  GLN GLN C . n 
C 3 30  LEU 30  30  30  LEU LEU C . n 
C 3 31  GLN 31  31  31  GLN GLN C . n 
C 3 32  LYS 32  32  32  LYS LYS C . n 
C 3 33  ASP 33  33  33  ASP ASP C . n 
C 3 34  LYS 34  34  34  LYS LYS C . n 
C 3 35  GLN 35  35  35  GLN GLN C . n 
C 3 36  VAL 36  36  36  VAL VAL C . n 
C 3 37  TYR 37  37  37  TYR TYR C . n 
C 3 38  ARG 38  38  38  ARG ARG C . n 
C 3 39  ALA 39  39  39  ALA ALA C . n 
C 3 40  THR 40  40  40  THR THR C . n 
C 3 41  HIS 41  41  41  HIS HIS C . n 
C 3 42  ARG 42  42  42  ARG ARG C . n 
C 3 43  LEU 43  43  43  LEU LEU C . n 
C 3 44  LEU 44  44  44  LEU LEU C . n 
C 3 45  LEU 45  45  45  LEU LEU C . n 
C 3 46  LEU 46  46  46  LEU LEU C . n 
C 3 47  GLY 47  47  47  GLY GLY C . n 
C 3 48  ALA 48  48  ?   ?   ?   C . n 
C 3 49  GLY 49  49  ?   ?   ?   C . n 
C 3 50  GLU 50  50  ?   ?   ?   C . n 
C 3 51  SER 51  51  51  SER SER C . n 
C 3 52  GLY 52  52  52  GLY GLY C . n 
C 3 53  LYS 53  53  53  LYS LYS C . n 
C 3 54  ASN 54  54  54  ASN ASN C . n 
C 3 55  THR 55  55  55  THR THR C . n 
C 3 56  ILE 56  56  56  ILE ILE C . n 
C 3 57  VAL 57  57  57  VAL VAL C . n 
C 3 58  LYS 58  58  58  LYS LYS C . n 
C 3 59  GLN 59  59  59  GLN GLN C . n 
C 3 60  MET 60  60  60  MET MET C . n 
C 3 61  ARG 61  61  61  ARG ARG C . n 
C 3 62  ILE 62  62  62  ILE ILE C . n 
C 3 63  LEU 63  63  63  LEU LEU C . n 
C 3 64  HIS 64  64  64  HIS HIS C . n 
C 3 65  VAL 65  65  ?   ?   ?   C . n 
C 3 66  ASN 66  66  ?   ?   ?   C . n 
C 3 67  GLY 67  67  ?   ?   ?   C . n 
C 3 68  PHE 68  68  ?   ?   ?   C . n 
C 3 69  ASN 69  69  ?   ?   ?   C . n 
C 3 70  GLY 70  70  ?   ?   ?   C . n 
C 3 71  GLU 71  71  ?   ?   ?   C . n 
C 3 72  GLY 72  72  ?   ?   ?   C . n 
C 3 73  GLY 73  73  ?   ?   ?   C . n 
C 3 74  GLU 74  74  ?   ?   ?   C . n 
C 3 75  GLU 75  75  ?   ?   ?   C . n 
C 3 76  ASP 76  76  ?   ?   ?   C . n 
C 3 77  PRO 77  77  ?   ?   ?   C . n 
C 3 78  GLN 78  78  ?   ?   ?   C . n 
C 3 79  ALA 79  79  ?   ?   ?   C . n 
C 3 80  ALA 80  80  ?   ?   ?   C . n 
C 3 81  ARG 81  81  ?   ?   ?   C . n 
C 3 82  SER 82  82  ?   ?   ?   C . n 
C 3 83  ASN 83  83  ?   ?   ?   C . n 
C 3 84  SER 84  84  ?   ?   ?   C . n 
C 3 85  ASP 85  85  ?   ?   ?   C . n 
C 3 86  GLY 86  86  ?   ?   ?   C . n 
C 3 87  GLU 87  87  ?   ?   ?   C . n 
C 3 88  LYS 88  88  ?   ?   ?   C . n 
C 3 89  ALA 89  89  ?   ?   ?   C . n 
C 3 90  THR 90  90  ?   ?   ?   C . n 
C 3 91  LYS 91  91  ?   ?   ?   C . n 
C 3 92  VAL 92  92  ?   ?   ?   C . n 
C 3 93  GLN 93  93  ?   ?   ?   C . n 
C 3 94  ASP 94  94  ?   ?   ?   C . n 
C 3 95  ILE 95  95  ?   ?   ?   C . n 
C 3 96  LYS 96  96  ?   ?   ?   C . n 
C 3 97  ASN 97  97  ?   ?   ?   C . n 
C 3 98  ASN 98  98  ?   ?   ?   C . n 
C 3 99  LEU 99  99  ?   ?   ?   C . n 
C 3 100 LYS 100 100 ?   ?   ?   C . n 
C 3 101 GLU 101 101 ?   ?   ?   C . n 
C 3 102 ALA 102 102 ?   ?   ?   C . n 
C 3 103 ILE 103 103 ?   ?   ?   C . n 
C 3 104 GLU 104 104 ?   ?   ?   C . n 
C 3 105 THR 105 105 ?   ?   ?   C . n 
C 3 106 ILE 106 106 ?   ?   ?   C . n 
C 3 107 VAL 107 107 ?   ?   ?   C . n 
C 3 108 ALA 108 108 ?   ?   ?   C . n 
C 3 109 ALA 109 109 ?   ?   ?   C . n 
C 3 110 MET 110 110 ?   ?   ?   C . n 
C 3 111 SER 111 111 ?   ?   ?   C . n 
C 3 112 ASN 112 112 ?   ?   ?   C . n 
C 3 113 LEU 113 113 ?   ?   ?   C . n 
C 3 114 VAL 114 114 ?   ?   ?   C . n 
C 3 115 PRO 115 115 ?   ?   ?   C . n 
C 3 116 PRO 116 116 ?   ?   ?   C . n 
C 3 117 VAL 117 117 ?   ?   ?   C . n 
C 3 118 GLU 118 118 ?   ?   ?   C . n 
C 3 119 LEU 119 119 ?   ?   ?   C . n 
C 3 120 ALA 120 120 ?   ?   ?   C . n 
C 3 121 ASN 121 121 ?   ?   ?   C . n 
C 3 122 PRO 122 122 ?   ?   ?   C . n 
C 3 123 GLU 123 123 ?   ?   ?   C . n 
C 3 124 ASN 124 124 ?   ?   ?   C . n 
C 3 125 GLN 125 125 ?   ?   ?   C . n 
C 3 126 PHE 126 126 ?   ?   ?   C . n 
C 3 127 ARG 127 127 ?   ?   ?   C . n 
C 3 128 VAL 128 128 ?   ?   ?   C . n 
C 3 129 ASP 129 129 ?   ?   ?   C . n 
C 3 130 TYR 130 130 ?   ?   ?   C . n 
C 3 131 ILE 131 131 ?   ?   ?   C . n 
C 3 132 LEU 132 132 ?   ?   ?   C . n 
C 3 133 SER 133 133 ?   ?   ?   C . n 
C 3 134 VAL 134 134 ?   ?   ?   C . n 
C 3 135 MET 135 135 ?   ?   ?   C . n 
C 3 136 ASN 136 136 ?   ?   ?   C . n 
C 3 137 VAL 137 137 ?   ?   ?   C . n 
C 3 138 PRO 138 138 ?   ?   ?   C . n 
C 3 139 ASP 139 139 ?   ?   ?   C . n 
C 3 140 PHE 140 140 ?   ?   ?   C . n 
C 3 141 ASP 141 141 ?   ?   ?   C . n 
C 3 142 PHE 142 142 ?   ?   ?   C . n 
C 3 143 PRO 143 143 ?   ?   ?   C . n 
C 3 144 PRO 144 144 ?   ?   ?   C . n 
C 3 145 GLU 145 145 ?   ?   ?   C . n 
C 3 146 PHE 146 146 ?   ?   ?   C . n 
C 3 147 TYR 147 147 ?   ?   ?   C . n 
C 3 148 GLU 148 148 ?   ?   ?   C . n 
C 3 149 HIS 149 149 ?   ?   ?   C . n 
C 3 150 ALA 150 150 ?   ?   ?   C . n 
C 3 151 LYS 151 151 ?   ?   ?   C . n 
C 3 152 ALA 152 152 ?   ?   ?   C . n 
C 3 153 LEU 153 153 ?   ?   ?   C . n 
C 3 154 TRP 154 154 ?   ?   ?   C . n 
C 3 155 GLU 155 155 ?   ?   ?   C . n 
C 3 156 ASP 156 156 ?   ?   ?   C . n 
C 3 157 GLU 157 157 ?   ?   ?   C . n 
C 3 158 GLY 158 158 ?   ?   ?   C . n 
C 3 159 VAL 159 159 ?   ?   ?   C . n 
C 3 160 ARG 160 160 ?   ?   ?   C . n 
C 3 161 ALA 161 161 ?   ?   ?   C . n 
C 3 162 CYS 162 162 ?   ?   ?   C . n 
C 3 163 TYR 163 163 ?   ?   ?   C . n 
C 3 164 GLU 164 164 ?   ?   ?   C . n 
C 3 165 ARG 165 165 ?   ?   ?   C . n 
C 3 166 SER 166 166 ?   ?   ?   C . n 
C 3 167 ASN 167 167 ?   ?   ?   C . n 
C 3 168 GLU 168 168 ?   ?   ?   C . n 
C 3 169 TYR 169 169 ?   ?   ?   C . n 
C 3 170 GLN 170 170 ?   ?   ?   C . n 
C 3 171 LEU 171 171 ?   ?   ?   C . n 
C 3 172 ILE 172 172 ?   ?   ?   C . n 
C 3 173 ASP 173 173 ?   ?   ?   C . n 
C 3 174 CYS 174 174 ?   ?   ?   C . n 
C 3 175 ALA 175 175 ?   ?   ?   C . n 
C 3 176 GLN 176 176 ?   ?   ?   C . n 
C 3 177 TYR 177 177 ?   ?   ?   C . n 
C 3 178 PHE 178 178 ?   ?   ?   C . n 
C 3 179 LEU 179 179 ?   ?   ?   C . n 
C 3 180 ASP 180 180 ?   ?   ?   C . n 
C 3 181 LYS 181 181 ?   ?   ?   C . n 
C 3 182 ILE 182 182 ?   ?   ?   C . n 
C 3 183 ASP 183 183 ?   ?   ?   C . n 
C 3 184 VAL 184 184 ?   ?   ?   C . n 
C 3 185 ILE 185 185 ?   ?   ?   C . n 
C 3 186 LYS 186 186 ?   ?   ?   C . n 
C 3 187 GLN 187 187 ?   ?   ?   C . n 
C 3 188 ALA 188 188 ?   ?   ?   C . n 
C 3 189 ASP 189 189 ?   ?   ?   C . n 
C 3 190 TYR 190 190 ?   ?   ?   C . n 
C 3 191 VAL 191 191 ?   ?   ?   C . n 
C 3 192 PRO 192 192 ?   ?   ?   C . n 
C 3 193 SER 193 193 ?   ?   ?   C . n 
C 3 194 ASP 194 194 ?   ?   ?   C . n 
C 3 195 GLN 195 195 ?   ?   ?   C . n 
C 3 196 ASP 196 196 ?   ?   ?   C . n 
C 3 197 LEU 197 197 ?   ?   ?   C . n 
C 3 198 LEU 198 198 ?   ?   ?   C . n 
C 3 199 ARG 199 199 ?   ?   ?   C . n 
C 3 200 CYS 200 200 ?   ?   ?   C . n 
C 3 201 ARG 201 201 ?   ?   ?   C . n 
C 3 202 VAL 202 202 ?   ?   ?   C . n 
C 3 203 LEU 203 203 ?   ?   ?   C . n 
C 3 204 THR 204 204 204 THR THR C . n 
C 3 205 SER 205 205 205 SER SER C . n 
C 3 206 GLY 206 206 206 GLY GLY C . n 
C 3 207 ILE 207 207 207 ILE ILE C . n 
C 3 208 PHE 208 208 208 PHE PHE C . n 
C 3 209 GLU 209 209 209 GLU GLU C . n 
C 3 210 THR 210 210 210 THR THR C . n 
C 3 211 LYS 211 211 211 LYS LYS C . n 
C 3 212 PHE 212 212 212 PHE PHE C . n 
C 3 213 GLN 213 213 213 GLN GLN C . n 
C 3 214 VAL 214 214 214 VAL VAL C . n 
C 3 215 ASP 215 215 215 ASP ASP C . n 
C 3 216 LYS 216 216 216 LYS LYS C . n 
C 3 217 VAL 217 217 217 VAL VAL C . n 
C 3 218 ASN 218 218 218 ASN ASN C . n 
C 3 219 PHE 219 219 219 PHE PHE C . n 
C 3 220 HIS 220 220 220 HIS HIS C . n 
C 3 221 MET 221 221 221 MET MET C . n 
C 3 222 PHE 222 222 222 PHE PHE C . n 
C 3 223 ASP 223 223 223 ASP ASP C . n 
C 3 224 VAL 224 224 224 VAL VAL C . n 
C 3 225 GLY 225 225 225 GLY GLY C . n 
C 3 226 ALA 226 226 226 ALA ALA C . n 
C 3 227 GLN 227 227 227 GLN GLN C . n 
C 3 228 ARG 228 228 228 ARG ARG C . n 
C 3 229 ASP 229 229 229 ASP ASP C . n 
C 3 230 GLU 230 230 230 GLU GLU C . n 
C 3 231 ARG 231 231 231 ARG ARG C . n 
C 3 232 ARG 232 232 232 ARG ARG C . n 
C 3 233 LYS 233 233 233 LYS LYS C . n 
C 3 234 TRP 234 234 234 TRP TRP C . n 
C 3 235 ILE 235 235 235 ILE ILE C . n 
C 3 236 GLN 236 236 236 GLN GLN C . n 
C 3 237 CYS 237 237 237 CYS CYS C . n 
C 3 238 PHE 238 238 238 PHE PHE C . n 
C 3 239 ASN 239 239 239 ASN ASN C . n 
C 3 240 ASP 240 240 240 ASP ASP C . n 
C 3 241 VAL 241 241 241 VAL VAL C . n 
C 3 242 THR 242 242 242 THR THR C . n 
C 3 243 ALA 243 243 243 ALA ALA C . n 
C 3 244 ILE 244 244 244 ILE ILE C . n 
C 3 245 ILE 245 245 245 ILE ILE C . n 
C 3 246 PHE 246 246 246 PHE PHE C . n 
C 3 247 VAL 247 247 247 VAL VAL C . n 
C 3 248 VAL 248 248 248 VAL VAL C . n 
C 3 249 ALA 249 249 249 ALA ALA C . n 
C 3 250 SER 250 250 250 SER SER C . n 
C 3 251 SER 251 251 251 SER SER C . n 
C 3 252 SER 252 252 252 SER SER C . n 
C 3 253 TYR 253 253 253 TYR TYR C . n 
C 3 254 ASN 254 254 ?   ?   ?   C . n 
C 3 255 MET 255 255 ?   ?   ?   C . n 
C 3 256 VAL 256 256 ?   ?   ?   C . n 
C 3 257 ILE 257 257 ?   ?   ?   C . n 
C 3 258 ARG 258 258 ?   ?   ?   C . n 
C 3 259 GLU 259 259 ?   ?   ?   C . n 
C 3 260 ASP 260 260 ?   ?   ?   C . n 
C 3 261 ASN 261 261 ?   ?   ?   C . n 
C 3 262 GLN 262 262 262 GLN GLN C . n 
C 3 263 THR 263 263 263 THR THR C . n 
C 3 264 ASN 264 264 264 ASN ASN C . n 
C 3 265 ARG 265 265 265 ARG ARG C . n 
C 3 266 LEU 266 266 266 LEU LEU C . n 
C 3 267 GLN 267 267 267 GLN GLN C . n 
C 3 268 ALA 268 268 268 ALA ALA C . n 
C 3 269 ALA 269 269 269 ALA ALA C . n 
C 3 270 LEU 270 270 270 LEU LEU C . n 
C 3 271 LYS 271 271 271 LYS LYS C . n 
C 3 272 LEU 272 272 272 LEU LEU C . n 
C 3 273 PHE 273 273 273 PHE PHE C . n 
C 3 274 ASP 274 274 274 ASP ASP C . n 
C 3 275 SER 275 275 275 SER SER C . n 
C 3 276 ILE 276 276 276 ILE ILE C . n 
C 3 277 TRP 277 277 277 TRP TRP C . n 
C 3 278 ASN 278 278 278 ASN ASN C . n 
C 3 279 ASN 279 279 279 ASN ASN C . n 
C 3 280 LYS 280 280 280 LYS LYS C . n 
C 3 281 TRP 281 281 281 TRP TRP C . n 
C 3 282 LEU 282 282 282 LEU LEU C . n 
C 3 283 ARG 283 283 283 ARG ARG C . n 
C 3 284 ASP 284 284 284 ASP ASP C . n 
C 3 285 THR 285 285 285 THR THR C . n 
C 3 286 SER 286 286 286 SER SER C . n 
C 3 287 VAL 287 287 287 VAL VAL C . n 
C 3 288 ILE 288 288 288 ILE ILE C . n 
C 3 289 LEU 289 289 289 LEU LEU C . n 
C 3 290 PHE 290 290 290 PHE PHE C . n 
C 3 291 LEU 291 291 291 LEU LEU C . n 
C 3 292 ASN 292 292 292 ASN ASN C . n 
C 3 293 LYS 293 293 293 LYS LYS C . n 
C 3 294 GLN 294 294 294 GLN GLN C . n 
C 3 295 ASP 295 295 295 ASP ASP C . n 
C 3 296 LEU 296 296 296 LEU LEU C . n 
C 3 297 LEU 297 297 297 LEU LEU C . n 
C 3 298 ALA 298 298 298 ALA ALA C . n 
C 3 299 GLU 299 299 299 GLU GLU C . n 
C 3 300 LYS 300 300 300 LYS LYS C . n 
C 3 301 VAL 301 301 301 VAL VAL C . n 
C 3 302 LEU 302 302 302 LEU LEU C . n 
C 3 303 ALA 303 303 303 ALA ALA C . n 
C 3 304 GLY 304 304 304 GLY GLY C . n 
C 3 305 LYS 305 305 305 LYS LYS C . n 
C 3 306 SER 306 306 306 SER SER C . n 
C 3 307 LYS 307 307 307 LYS LYS C . n 
C 3 308 ILE 308 308 308 ILE ILE C . n 
C 3 309 GLU 309 309 309 GLU GLU C . n 
C 3 310 ASP 310 310 310 ASP ASP C . n 
C 3 311 TYR 311 311 311 TYR TYR C . n 
C 3 312 PHE 312 312 312 PHE PHE C . n 
C 3 313 PRO 313 313 313 PRO PRO C . n 
C 3 314 GLU 314 314 314 GLU GLU C . n 
C 3 315 PHE 315 315 315 PHE PHE C . n 
C 3 316 ALA 316 316 316 ALA ALA C . n 
C 3 317 ARG 317 317 317 ARG ARG C . n 
C 3 318 TYR 318 318 318 TYR TYR C . n 
C 3 319 THR 319 319 319 THR THR C . n 
C 3 320 THR 320 320 320 THR THR C . n 
C 3 321 PRO 321 321 321 PRO PRO C . n 
C 3 322 GLU 322 322 322 GLU GLU C . n 
C 3 323 ASP 323 323 323 ASP ASP C . n 
C 3 324 ALA 324 324 324 ALA ALA C . n 
C 3 325 THR 325 325 325 THR THR C . n 
C 3 326 PRO 326 326 326 PRO PRO C . n 
C 3 327 GLU 327 327 327 GLU GLU C . n 
C 3 328 PRO 328 328 328 PRO PRO C . n 
C 3 329 GLY 329 329 329 GLY GLY C . n 
C 3 330 GLU 330 330 330 GLU GLU C . n 
C 3 331 ASP 331 331 331 ASP ASP C . n 
C 3 332 PRO 332 332 332 PRO PRO C . n 
C 3 333 ARG 333 333 333 ARG ARG C . n 
C 3 334 VAL 334 334 334 VAL VAL C . n 
C 3 335 THR 335 335 335 THR THR C . n 
C 3 336 ARG 336 336 336 ARG ARG C . n 
C 3 337 ALA 337 337 337 ALA ALA C . n 
C 3 338 LYS 338 338 338 LYS LYS C . n 
C 3 339 TYR 339 339 339 TYR TYR C . n 
C 3 340 PHE 340 340 340 PHE PHE C . n 
C 3 341 ILE 341 341 341 ILE ILE C . n 
C 3 342 ARG 342 342 342 ARG ARG C . n 
C 3 343 ASP 343 343 343 ASP ASP C . n 
C 3 344 GLU 344 344 344 GLU GLU C . n 
C 3 345 PHE 345 345 345 PHE PHE C . n 
C 3 346 LEU 346 346 346 LEU LEU C . n 
C 3 347 ARG 347 347 347 ARG ARG C . n 
C 3 348 ILE 348 348 348 ILE ILE C . n 
C 3 349 SER 349 349 349 SER SER C . n 
C 3 350 THR 350 350 350 THR THR C . n 
C 3 351 ALA 351 351 351 ALA ALA C . n 
C 3 352 SER 352 352 352 SER SER C . n 
C 3 353 GLY 353 353 353 GLY GLY C . n 
C 3 354 ASP 354 354 354 ASP ASP C . n 
C 3 355 GLY 355 355 355 GLY GLY C . n 
C 3 356 ARG 356 356 356 ARG ARG C . n 
C 3 357 HIS 357 357 357 HIS HIS C . n 
C 3 358 TYR 358 358 358 TYR TYR C . n 
C 3 359 CYS 359 359 359 CYS CYS C . n 
C 3 360 TYR 360 360 360 TYR TYR C . n 
C 3 361 PRO 361 361 361 PRO PRO C . n 
C 3 362 HIS 362 362 362 HIS HIS C . n 
C 3 363 PHE 363 363 363 PHE PHE C . n 
C 3 364 THR 364 364 364 THR THR C . n 
C 3 365 CYS 365 365 365 CYS CYS C . n 
C 3 366 ALA 366 366 366 ALA ALA C . n 
C 3 367 VAL 367 367 367 VAL VAL C . n 
C 3 368 ASP 368 368 368 ASP ASP C . n 
C 3 369 THR 369 369 369 THR THR C . n 
C 3 370 GLU 370 370 370 GLU GLU C . n 
C 3 371 ASN 371 371 371 ASN ASN C . n 
C 3 372 ILE 372 372 372 ILE ILE C . n 
C 3 373 ARG 373 373 373 ARG ARG C . n 
C 3 374 ARG 374 374 374 ARG ARG C . n 
C 3 375 VAL 375 375 375 VAL VAL C . n 
C 3 376 PHE 376 376 376 PHE PHE C . n 
C 3 377 ASN 377 377 377 ASN ASN C . n 
C 3 378 ASP 378 378 378 ASP ASP C . n 
C 3 379 CYS 379 379 379 CYS CYS C . n 
C 3 380 ARG 380 380 380 ARG ARG C . n 
C 3 381 ASP 381 381 381 ASP ASP C . n 
C 3 382 ILE 382 382 382 ILE ILE C . n 
C 3 383 ILE 383 383 383 ILE ILE C . n 
C 3 384 GLN 384 384 384 GLN GLN C . n 
C 3 385 ARG 385 385 385 ARG ARG C . n 
C 3 386 MET 386 386 386 MET MET C . n 
C 3 387 HIS 387 387 387 HIS HIS C . n 
C 3 388 LEU 388 388 388 LEU LEU C . n 
C 3 389 ARG 389 389 389 ARG ARG C . n 
C 3 390 GLN 390 390 390 GLN GLN C . n 
C 3 391 TYR 391 391 391 TYR TYR C . n 
C 3 392 GLU 392 392 392 GLU GLU C . n 
C 3 393 LEU 393 393 393 LEU LEU C . n 
C 3 394 LEU 394 394 394 LEU LEU C . n 
D 4 1   MET 1   1   ?   ?   ?   G . n 
D 4 2   ALA 2   2   ?   ?   ?   G . n 
D 4 3   SER 3   3   ?   ?   ?   G . n 
D 4 4   ASN 4   4   ?   ?   ?   G . n 
D 4 5   ASN 5   5   5   ASN ASN G . n 
D 4 6   THR 6   6   6   THR THR G . n 
D 4 7   ALA 7   7   7   ALA ALA G . n 
D 4 8   SER 8   8   8   SER SER G . n 
D 4 9   ILE 9   9   9   ILE ILE G . n 
D 4 10  ALA 10  10  10  ALA ALA G . n 
D 4 11  GLN 11  11  11  GLN GLN G . n 
D 4 12  ALA 12  12  12  ALA ALA G . n 
D 4 13  ARG 13  13  13  ARG ARG G . n 
D 4 14  LYS 14  14  14  LYS LYS G . n 
D 4 15  LEU 15  15  15  LEU LEU G . n 
D 4 16  VAL 16  16  16  VAL VAL G . n 
D 4 17  GLU 17  17  17  GLU GLU G . n 
D 4 18  GLN 18  18  18  GLN GLN G . n 
D 4 19  LEU 19  19  19  LEU LEU G . n 
D 4 20  LYS 20  20  20  LYS LYS G . n 
D 4 21  MET 21  21  21  MET MET G . n 
D 4 22  GLU 22  22  22  GLU GLU G . n 
D 4 23  ALA 23  23  23  ALA ALA G . n 
D 4 24  ASN 24  24  24  ASN ASN G . n 
D 4 25  ILE 25  25  25  ILE ILE G . n 
D 4 26  ASP 26  26  26  ASP ASP G . n 
D 4 27  ARG 27  27  27  ARG ARG G . n 
D 4 28  ILE 28  28  28  ILE ILE G . n 
D 4 29  LYS 29  29  29  LYS LYS G . n 
D 4 30  VAL 30  30  30  VAL VAL G . n 
D 4 31  SER 31  31  31  SER SER G . n 
D 4 32  LYS 32  32  32  LYS LYS G . n 
D 4 33  ALA 33  33  33  ALA ALA G . n 
D 4 34  ALA 34  34  34  ALA ALA G . n 
D 4 35  ALA 35  35  35  ALA ALA G . n 
D 4 36  ASP 36  36  36  ASP ASP G . n 
D 4 37  LEU 37  37  37  LEU LEU G . n 
D 4 38  MET 38  38  38  MET MET G . n 
D 4 39  ALA 39  39  39  ALA ALA G . n 
D 4 40  TYR 40  40  40  TYR TYR G . n 
D 4 41  CYS 41  41  41  CYS CYS G . n 
D 4 42  GLU 42  42  42  GLU GLU G . n 
D 4 43  ALA 43  43  43  ALA ALA G . n 
D 4 44  HIS 44  44  44  HIS HIS G . n 
D 4 45  ALA 45  45  45  ALA ALA G . n 
D 4 46  LYS 46  46  46  LYS LYS G . n 
D 4 47  GLU 47  47  47  GLU GLU G . n 
D 4 48  ASP 48  48  48  ASP ASP G . n 
D 4 49  PRO 49  49  49  PRO PRO G . n 
D 4 50  LEU 50  50  50  LEU LEU G . n 
D 4 51  LEU 51  51  51  LEU LEU G . n 
D 4 52  THR 52  52  52  THR THR G . n 
D 4 53  PRO 53  53  53  PRO PRO G . n 
D 4 54  VAL 54  54  54  VAL VAL G . n 
D 4 55  PRO 55  55  55  PRO PRO G . n 
D 4 56  ALA 56  56  56  ALA ALA G . n 
D 4 57  SER 57  57  57  SER SER G . n 
D 4 58  GLU 58  58  58  GLU GLU G . n 
D 4 59  ASN 59  59  59  ASN ASN G . n 
D 4 60  PRO 60  60  60  PRO PRO G . n 
D 4 61  PHE 61  61  61  PHE PHE G . n 
D 4 62  ARG 62  62  62  ARG ARG G . n 
D 4 63  GLU 63  63  ?   ?   ?   G . n 
D 4 64  LYS 64  64  ?   ?   ?   G . n 
D 4 65  LYS 65  65  ?   ?   ?   G . n 
D 4 66  PHE 66  66  ?   ?   ?   G . n 
D 4 67  PHE 67  67  ?   ?   ?   G . n 
D 4 68  CYS 68  68  ?   ?   ?   G . n 
D 4 69  ALA 69  69  ?   ?   ?   G . n 
D 4 70  ILE 70  70  ?   ?   ?   G . n 
D 4 71  LEU 71  71  ?   ?   ?   G . n 
E 5 1   GLN 1   1   1   GLN GLN N . n 
E 5 2   VAL 2   2   2   VAL VAL N . n 
E 5 3   GLN 3   3   3   GLN GLN N . n 
E 5 4   LEU 4   4   4   LEU LEU N . n 
E 5 5   GLN 5   5   5   GLN GLN N . n 
E 5 6   GLU 6   6   6   GLU GLU N . n 
E 5 7   SER 7   7   7   SER SER N . n 
E 5 8   GLY 8   8   8   GLY GLY N . n 
E 5 9   GLY 9   9   9   GLY GLY N . n 
E 5 10  GLY 10  10  10  GLY GLY N . n 
E 5 11  LEU 11  11  11  LEU LEU N . n 
E 5 12  VAL 12  12  12  VAL VAL N . n 
E 5 13  GLN 13  13  13  GLN GLN N . n 
E 5 14  PRO 14  14  14  PRO PRO N . n 
E 5 15  GLY 15  15  15  GLY GLY N . n 
E 5 16  GLY 16  16  16  GLY GLY N . n 
E 5 17  SER 17  17  17  SER SER N . n 
E 5 18  LEU 18  18  18  LEU LEU N . n 
E 5 19  ARG 19  19  19  ARG ARG N . n 
E 5 20  LEU 20  20  20  LEU LEU N . n 
E 5 21  SER 21  21  21  SER SER N . n 
E 5 22  CYS 22  22  22  CYS CYS N . n 
E 5 23  ALA 23  23  23  ALA ALA N . n 
E 5 24  ALA 24  24  24  ALA ALA N . n 
E 5 25  SER 25  25  25  SER SER N . n 
E 5 26  GLY 26  26  26  GLY GLY N . n 
E 5 27  PHE 27  27  27  PHE PHE N . n 
E 5 28  THR 28  28  28  THR THR N . n 
E 5 29  PHE 29  29  29  PHE PHE N . n 
E 5 30  SER 30  30  30  SER SER N . n 
E 5 31  ASN 31  31  31  ASN ASN N . n 
E 5 32  TYR 32  32  32  TYR TYR N . n 
E 5 33  LYS 33  33  33  LYS LYS N . n 
E 5 34  MET 34  34  34  MET MET N . n 
E 5 35  ASN 35  35  35  ASN ASN N . n 
E 5 36  TRP 36  36  36  TRP TRP N . n 
E 5 37  VAL 37  37  37  VAL VAL N . n 
E 5 38  ARG 38  38  38  ARG ARG N . n 
E 5 39  GLN 39  39  39  GLN GLN N . n 
E 5 40  ALA 40  40  40  ALA ALA N . n 
E 5 41  PRO 41  41  41  PRO PRO N . n 
E 5 42  GLY 42  42  42  GLY GLY N . n 
E 5 43  LYS 43  43  43  LYS LYS N . n 
E 5 44  GLY 44  44  44  GLY GLY N . n 
E 5 45  LEU 45  45  45  LEU LEU N . n 
E 5 46  GLU 46  46  46  GLU GLU N . n 
E 5 47  TRP 47  47  47  TRP TRP N . n 
E 5 48  VAL 48  48  48  VAL VAL N . n 
E 5 49  SER 49  49  49  SER SER N . n 
E 5 50  ASP 50  50  50  ASP ASP N . n 
E 5 51  ILE 51  51  51  ILE ILE N . n 
E 5 52  SER 52  52  52  SER SER N . n 
E 5 53  GLN 53  53  53  GLN GLN N . n 
E 5 54  SER 54  54  54  SER SER N . n 
E 5 55  GLY 55  55  55  GLY GLY N . n 
E 5 56  ALA 56  56  56  ALA ALA N . n 
E 5 57  SER 57  57  57  SER SER N . n 
E 5 58  ILE 58  58  58  ILE ILE N . n 
E 5 59  SER 59  59  59  SER SER N . n 
E 5 60  TYR 60  60  60  TYR TYR N . n 
E 5 61  THR 61  61  61  THR THR N . n 
E 5 62  GLY 62  62  62  GLY GLY N . n 
E 5 63  SER 63  63  63  SER SER N . n 
E 5 64  VAL 64  64  64  VAL VAL N . n 
E 5 65  LYS 65  65  65  LYS LYS N . n 
E 5 66  GLY 66  66  66  GLY GLY N . n 
E 5 67  ARG 67  67  67  ARG ARG N . n 
E 5 68  PHE 68  68  68  PHE PHE N . n 
E 5 69  THR 69  69  69  THR THR N . n 
E 5 70  ILE 70  70  70  ILE ILE N . n 
E 5 71  SER 71  71  71  SER SER N . n 
E 5 72  ARG 72  72  72  ARG ARG N . n 
E 5 73  ASP 73  73  73  ASP ASP N . n 
E 5 74  ASN 74  74  74  ASN ASN N . n 
E 5 75  ALA 75  75  75  ALA ALA N . n 
E 5 76  LYS 76  76  76  LYS LYS N . n 
E 5 77  ASN 77  77  77  ASN ASN N . n 
E 5 78  THR 78  78  78  THR THR N . n 
E 5 79  LEU 79  79  79  LEU LEU N . n 
E 5 80  TYR 80  80  80  TYR TYR N . n 
E 5 81  LEU 81  81  81  LEU LEU N . n 
E 5 82  GLN 82  82  82  GLN GLN N . n 
E 5 83  MET 83  83  83  MET MET N . n 
E 5 84  ASN 84  84  84  ASN ASN N . n 
E 5 85  SER 85  85  85  SER SER N . n 
E 5 86  LEU 86  86  86  LEU LEU N . n 
E 5 87  LYS 87  87  87  LYS LYS N . n 
E 5 88  PRO 88  88  88  PRO PRO N . n 
E 5 89  GLU 89  89  89  GLU GLU N . n 
E 5 90  ASP 90  90  90  ASP ASP N . n 
E 5 91  THR 91  91  91  THR THR N . n 
E 5 92  ALA 92  92  92  ALA ALA N . n 
E 5 93  VAL 93  93  93  VAL VAL N . n 
E 5 94  TYR 94  94  94  TYR TYR N . n 
E 5 95  TYR 95  95  95  TYR TYR N . n 
E 5 96  CYS 96  96  96  CYS CYS N . n 
E 5 97  ALA 97  97  97  ALA ALA N . n 
E 5 98  ARG 98  98  98  ARG ARG N . n 
E 5 99  CYS 99  99  99  CYS CYS N . n 
E 5 100 PRO 100 100 100 PRO PRO N . n 
E 5 101 ALA 101 101 101 ALA ALA N . n 
E 5 102 PRO 102 102 102 PRO PRO N . n 
E 5 103 PHE 103 103 103 PHE PHE N . n 
E 5 104 THR 104 104 104 THR THR N . n 
E 5 105 ARG 105 105 105 ARG ARG N . n 
E 5 106 ASP 106 106 106 ASP ASP N . n 
E 5 107 CYS 107 107 107 CYS CYS N . n 
E 5 108 PHE 108 108 108 PHE PHE N . n 
E 5 109 ASP 109 109 109 ASP ASP N . n 
E 5 110 VAL 110 110 110 VAL VAL N . n 
E 5 111 THR 111 111 111 THR THR N . n 
E 5 112 SER 112 112 112 SER SER N . n 
E 5 113 THR 113 113 113 THR THR N . n 
E 5 114 THR 114 114 114 THR THR N . n 
E 5 115 TYR 115 115 115 TYR TYR N . n 
E 5 116 ALA 116 116 116 ALA ALA N . n 
E 5 117 TYR 117 117 117 TYR TYR N . n 
E 5 118 ARG 118 118 118 ARG ARG N . n 
E 5 119 GLY 119 119 119 GLY GLY N . n 
E 5 120 GLN 120 120 120 GLN GLN N . n 
E 5 121 GLY 121 121 121 GLY GLY N . n 
E 5 122 THR 122 122 122 THR THR N . n 
E 5 123 GLN 123 123 123 GLN GLN N . n 
E 5 124 VAL 124 124 124 VAL VAL N . n 
E 5 125 THR 125 125 125 THR THR N . n 
E 5 126 VAL 126 126 126 VAL VAL N . n 
E 5 127 SER 127 127 127 SER SER N . n 
E 5 128 SER 128 128 128 SER SER N . n 
E 5 129 HIS 129 129 ?   ?   ?   N . n 
E 5 130 HIS 130 130 ?   ?   ?   N . n 
E 5 131 HIS 131 131 ?   ?   ?   N . n 
E 5 132 HIS 132 132 ?   ?   ?   N . n 
E 5 133 HIS 133 133 ?   ?   ?   N . n 
E 5 134 HIS 134 134 ?   ?   ?   N . n 
E 5 135 GLU 135 135 ?   ?   ?   N . n 
E 5 136 PRO 136 136 ?   ?   ?   N . n 
E 5 137 GLU 137 137 ?   ?   ?   N . n 
E 5 138 ALA 138 138 ?   ?   ?   N . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 180 ? CG  ? A ARG 180 CG  
2  1 Y 1 A ARG 180 ? CD  ? A ARG 180 CD  
3  1 Y 1 A ARG 180 ? NE  ? A ARG 180 NE  
4  1 Y 1 A ARG 180 ? CZ  ? A ARG 180 CZ  
5  1 Y 1 A ARG 180 ? NH1 ? A ARG 180 NH1 
6  1 Y 1 A ARG 180 ? NH2 ? A ARG 180 NH2 
7  1 Y 1 A ARG 213 ? CG  ? A ARG 213 CG  
8  1 Y 1 A ARG 213 ? CD  ? A ARG 213 CD  
9  1 Y 1 A ARG 213 ? NE  ? A ARG 213 NE  
10 1 Y 1 A ARG 213 ? CZ  ? A ARG 213 CZ  
11 1 Y 1 A ARG 213 ? NH1 ? A ARG 213 NH1 
12 1 Y 1 A ARG 213 ? NH2 ? A ARG 213 NH2 
13 1 Y 1 B SER 2   ? OG  ? B SER 12  OG  
14 1 Y 1 B ARG 42  ? CG  ? B ARG 52  CG  
15 1 Y 1 B ARG 42  ? CD  ? B ARG 52  CD  
16 1 Y 1 B ARG 42  ? NE  ? B ARG 52  NE  
17 1 Y 1 B ARG 42  ? CZ  ? B ARG 52  CZ  
18 1 Y 1 B ARG 42  ? NH1 ? B ARG 52  NH1 
19 1 Y 1 B ARG 42  ? NH2 ? B ARG 52  NH2 
20 1 Y 1 B ARG 129 ? CG  ? B ARG 139 CG  
21 1 Y 1 B ARG 129 ? CD  ? B ARG 139 CD  
22 1 Y 1 B ARG 129 ? NE  ? B ARG 139 NE  
23 1 Y 1 B ARG 129 ? CZ  ? B ARG 139 CZ  
24 1 Y 1 B ARG 129 ? NH1 ? B ARG 139 NH1 
25 1 Y 1 B ARG 129 ? NH2 ? B ARG 139 NH2 
26 1 Y 1 C LYS 8   ? CG  ? C LYS 8   CG  
27 1 Y 1 C LYS 8   ? CD  ? C LYS 8   CD  
28 1 Y 1 C LYS 8   ? CE  ? C LYS 8   CE  
29 1 Y 1 C LYS 8   ? NZ  ? C LYS 8   NZ  
30 1 Y 1 C LYS 58  ? CG  ? C LYS 58  CG  
31 1 Y 1 C LYS 58  ? CD  ? C LYS 58  CD  
32 1 Y 1 C LYS 58  ? CE  ? C LYS 58  CE  
33 1 Y 1 C LYS 58  ? NZ  ? C LYS 58  NZ  
34 1 Y 1 C ARG 61  ? CG  ? C ARG 61  CG  
35 1 Y 1 C ARG 61  ? CD  ? C ARG 61  CD  
36 1 Y 1 C ARG 61  ? NE  ? C ARG 61  NE  
37 1 Y 1 C ARG 61  ? CZ  ? C ARG 61  CZ  
38 1 Y 1 C ARG 61  ? NH1 ? C ARG 61  NH1 
39 1 Y 1 C ARG 61  ? NH2 ? C ARG 61  NH2 
40 1 Y 1 C ILE 62  ? CG1 ? C ILE 62  CG1 
41 1 Y 1 C ILE 62  ? CG2 ? C ILE 62  CG2 
42 1 Y 1 C ILE 62  ? CD1 ? C ILE 62  CD1 
43 1 Y 1 C LEU 63  ? CG  ? C LEU 63  CG  
44 1 Y 1 C LEU 63  ? CD1 ? C LEU 63  CD1 
45 1 Y 1 C LEU 63  ? CD2 ? C LEU 63  CD2 
46 1 Y 1 C HIS 64  ? CG  ? C HIS 64  CG  
47 1 Y 1 C HIS 64  ? ND1 ? C HIS 64  ND1 
48 1 Y 1 C HIS 64  ? CD2 ? C HIS 64  CD2 
49 1 Y 1 C HIS 64  ? CE1 ? C HIS 64  CE1 
50 1 Y 1 C HIS 64  ? NE2 ? C HIS 64  NE2 
51 1 Y 1 C GLN 262 ? CG  ? C GLN 262 CG  
52 1 Y 1 C GLN 262 ? CD  ? C GLN 262 CD  
53 1 Y 1 C GLN 262 ? OE1 ? C GLN 262 OE1 
54 1 Y 1 C GLN 262 ? NE2 ? C GLN 262 NE2 
55 1 Y 1 C LYS 305 ? CG  ? C LYS 305 CG  
56 1 Y 1 C LYS 305 ? CD  ? C LYS 305 CD  
57 1 Y 1 C LYS 305 ? CE  ? C LYS 305 CE  
58 1 Y 1 C LYS 305 ? NZ  ? C LYS 305 NZ  
59 1 Y 1 C ASP 368 ? CG  ? C ASP 368 CG  
60 1 Y 1 C ASP 368 ? OD1 ? C ASP 368 OD1 
61 1 Y 1 C ASP 368 ? OD2 ? C ASP 368 OD2 
62 1 Y 1 G ASN 5   ? CG  ? D ASN 5   CG  
63 1 Y 1 G ASN 5   ? OD1 ? D ASN 5   OD1 
64 1 Y 1 G ASN 5   ? ND2 ? D ASN 5   ND2 
65 1 Y 1 G GLU 58  ? CG  ? D GLU 58  CG  
66 1 Y 1 G GLU 58  ? CD  ? D GLU 58  CD  
67 1 Y 1 G GLU 58  ? OE1 ? D GLU 58  OE1 
68 1 Y 1 G GLU 58  ? OE2 ? D GLU 58  OE2 
69 1 Y 1 N LYS 43  ? CG  ? E LYS 43  CG  
70 1 Y 1 N LYS 43  ? CD  ? E LYS 43  CD  
71 1 Y 1 N LYS 43  ? CE  ? E LYS 43  CE  
72 1 Y 1 N LYS 43  ? NZ  ? E LYS 43  NZ  
73 1 Y 1 N LYS 76  ? CG  ? E LYS 76  CG  
74 1 Y 1 N LYS 76  ? CD  ? E LYS 76  CD  
75 1 Y 1 N LYS 76  ? CE  ? E LYS 76  CE  
76 1 Y 1 N LYS 76  ? NZ  ? E LYS 76  NZ  
77 1 Y 1 N ARG 105 ? CG  ? E ARG 105 CG  
78 1 Y 1 N ARG 105 ? CD  ? E ARG 105 CD  
79 1 Y 1 N ARG 105 ? NE  ? E ARG 105 NE  
80 1 Y 1 N ARG 105 ? CZ  ? E ARG 105 CZ  
81 1 Y 1 N ARG 105 ? NH1 ? E ARG 105 NH1 
82 1 Y 1 N ARG 105 ? NH2 ? E ARG 105 NH2 
83 1 Y 1 N SER 128 ? OG  ? E SER 128 OG  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8TYW 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8TYW 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8TYW 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8TYW 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 8041  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.763 ? 10926 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.932 ? 1103  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.049 ? 1262  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.006 ? 1393  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8TYW 
_struct.title                        'cryo-EM structure of GPR6-Gs-Nb35 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8TYW 
_struct_keywords.text            'GPR6, Gs, Nb, cryo-EM, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GPR6_HUMAN  P46095 ? 1 
;MNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNPWDVLLC
VSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLL
AITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGI
MLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATY
NSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFRSRSPSEV
;
1 
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2 
3 UNP GNAS2_HUMAN P63092 ? 3 
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAA
RSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVR
ACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND
VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT
PEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
1 
4 UNP GBG2_HUMAN  P59768 ? 4 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1 
5 PDB 8TYW        8TYW   ? 5 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8TYW A 1  ? 362 ? P46095 1 ? 362 ? 1 362 
2 2 8TYW B 12 ? 350 ? P62873 2 ? 340 ? 2 340 
3 3 8TYW C 1  ? 394 ? P63092 1 ? 394 ? 1 394 
4 4 8TYW G 1  ? 71  ? P59768 1 ? 71  ? 1 71  
5 5 8TYW N 1  ? 138 ? 8TYW   1 ? 138 ? 1 138 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8TYW HIS A 363 ? UNP P46095 ?   ?   'expression tag'      363 1  
1 8TYW HIS A 364 ? UNP P46095 ?   ?   'expression tag'      364 2  
1 8TYW HIS A 365 ? UNP P46095 ?   ?   'expression tag'      365 3  
1 8TYW HIS A 366 ? UNP P46095 ?   ?   'expression tag'      366 4  
1 8TYW HIS A 367 ? UNP P46095 ?   ?   'expression tag'      367 5  
1 8TYW HIS A 368 ? UNP P46095 ?   ?   'expression tag'      368 6  
1 8TYW HIS A 369 ? UNP P46095 ?   ?   'expression tag'      369 7  
1 8TYW HIS A 370 ? UNP P46095 ?   ?   'expression tag'      370 8  
1 8TYW HIS A 371 ? UNP P46095 ?   ?   'expression tag'      371 9  
1 8TYW HIS A 372 ? UNP P46095 ?   ?   'expression tag'      372 10 
2 8TYW MET B 1   ? UNP P62873 ?   ?   'expression tag'      -9  11 
2 8TYW HIS B 2   ? UNP P62873 ?   ?   'expression tag'      -8  12 
2 8TYW HIS B 3   ? UNP P62873 ?   ?   'expression tag'      -7  13 
2 8TYW HIS B 4   ? UNP P62873 ?   ?   'expression tag'      -6  14 
2 8TYW HIS B 5   ? UNP P62873 ?   ?   'expression tag'      -5  15 
2 8TYW HIS B 6   ? UNP P62873 ?   ?   'expression tag'      -4  16 
2 8TYW HIS B 7   ? UNP P62873 ?   ?   'expression tag'      -3  17 
2 8TYW GLY B 8   ? UNP P62873 ?   ?   'expression tag'      -2  18 
2 8TYW SER B 9   ? UNP P62873 ?   ?   'expression tag'      -1  19 
2 8TYW SER B 10  ? UNP P62873 ?   ?   'expression tag'      0   20 
2 8TYW GLY B 11  ? UNP P62873 ?   ?   'expression tag'      1   21 
3 8TYW ASN C 54  ? UNP P63092 SER 54  'engineered mutation' 54  22 
3 8TYW ALA C 226 ? UNP P63092 GLY 226 'engineered mutation' 226 23 
3 8TYW ALA C 268 ? UNP P63092 GLU 268 'engineered mutation' 268 24 
3 8TYW LYS C 271 ? UNP P63092 ASN 271 'engineered mutation' 271 25 
3 8TYW ASP C 274 ? UNP P63092 LYS 274 'engineered mutation' 274 26 
3 8TYW LYS C 280 ? UNP P63092 ARG 280 'engineered mutation' 280 27 
3 8TYW ASP C 284 ? UNP P63092 THR 284 'engineered mutation' 284 28 
3 8TYW THR C 285 ? UNP P63092 ILE 285 'engineered mutation' 285 29 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 73  ? THR A 100 ? ASN A 73  THR A 100 1 ? 28 
HELX_P HELX_P2  AA2 THR A 105 ? VAL A 135 ? THR A 105 VAL A 135 1 ? 31 
HELX_P HELX_P3  AA3 SER A 137 ? ASN A 172 ? SER A 137 ASN A 172 1 ? 36 
HELX_P HELX_P4  AA4 ALA A 173 ? TYR A 176 ? ALA A 173 TYR A 176 5 ? 4  
HELX_P HELX_P5  AA5 SER A 178 ? GLY A 206 ? SER A 178 GLY A 206 1 ? 29 
HELX_P HELX_P6  AA6 ALA A 223 ? GLN A 263 ? ALA A 223 GLN A 263 1 ? 41 
HELX_P HELX_P7  AA7 ARG A 275 ? GLY A 302 ? ARG A 275 GLY A 302 1 ? 28 
HELX_P HELX_P8  AA8 PRO A 307 ? ALA A 330 ? PRO A 307 ALA A 330 1 ? 24 
HELX_P HELX_P9  AA9 ASN A 333 ? LEU A 344 ? ASN A 333 LEU A 344 1 ? 12 
HELX_P HELX_P10 AB1 GLU B 13  ? CYS B 35  ? GLU B 3   CYS B 25  1 ? 23 
HELX_P HELX_P11 AB2 THR B 39  ? ILE B 43  ? THR B 29  ILE B 33  5 ? 5  
HELX_P HELX_P12 AB3 THR C 9   ? ALA C 39  ? THR C 9   ALA C 39  1 ? 31 
HELX_P HELX_P13 AB4 GLY C 52  ? HIS C 64  ? GLY C 52  HIS C 64  1 ? 13 
HELX_P HELX_P14 AB5 TRP C 234 ? PHE C 238 ? TRP C 234 PHE C 238 5 ? 5  
HELX_P HELX_P15 AB6 ASN C 264 ? ASN C 278 ? ASN C 264 ASN C 278 1 ? 15 
HELX_P HELX_P16 AB7 GLN C 294 ? GLY C 304 ? GLN C 294 GLY C 304 1 ? 11 
HELX_P HELX_P17 AB8 ILE C 308 ? ALA C 316 ? ILE C 308 ALA C 316 5 ? 9  
HELX_P HELX_P18 AB9 ASP C 331 ? GLY C 353 ? ASP C 331 GLY C 353 1 ? 23 
HELX_P HELX_P19 AC1 GLU C 370 ? TYR C 391 ? GLU C 370 TYR C 391 1 ? 22 
HELX_P HELX_P20 AC2 THR D 6   ? ASN D 24  ? THR G 6   ASN G 24  1 ? 19 
HELX_P HELX_P21 AC3 LYS D 29  ? HIS D 44  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P22 AC4 LYS E 87  ? THR E 91  ? LYS N 87  THR N 91  5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 209 SG ? ? ? 1_555 A CYS 216 SG ? ? A CYS 209 A CYS 216 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf2 disulf ? ? E CYS 22  SG ? ? ? 1_555 E CYS 96  SG ? ? N CYS 22  N CYS 96  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf3 disulf ? ? E CYS 99  SG ? ? ? 1_555 E CYS 107 SG ? ? N CYS 99  N CYS 107 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 209 ? CYS A 216 ? CYS A 209 ? 1_555 CYS A 216 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS E 22  ? CYS E 96  ? CYS N 22  ? 1_555 CYS N 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 99  ? CYS E 107 ? CYS N 99  ? 1_555 CYS N 107 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          ARG 
_struct_mon_prot_cis.label_seq_id           220 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           ARG 
_struct_mon_prot_cis.auth_seq_id            220 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    221 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     221 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       0.56 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG B 56  ? ARG B 62  ? ARG B 46  ARG B 52  
AA1 2 PHE B 345 ? ASN B 350 ? PHE B 335 ASN B 340 
AA1 3 VAL B 337 ? GLY B 340 ? VAL B 327 GLY B 330 
AA1 4 CYS B 327 ? VAL B 330 ? CYS B 317 VAL B 320 
AA2 1 ILE B 68  ? TRP B 73  ? ILE B 58  TRP B 63  
AA2 2 LEU B 79  ? SER B 84  ? LEU B 69  SER B 74  
AA2 3 LYS B 88  ? ASP B 93  ? LYS B 78  ASP B 83  
AA2 4 ASN B 98  ? PRO B 104 ? ASN B 88  PRO B 94  
AA3 1 VAL B 110 ? TYR B 115 ? VAL B 100 TYR B 105 
AA3 2 TYR B 121 ? GLY B 126 ? TYR B 111 GLY B 116 
AA3 3 CYS B 131 ? ASN B 135 ? CYS B 121 ASN B 125 
AA3 4 ARG B 144 ? LEU B 149 ? ARG B 134 LEU B 139 
AA4 1 LEU B 156 ? PHE B 161 ? LEU B 146 PHE B 151 
AA4 2 GLN B 166 ? SER B 171 ? GLN B 156 SER B 161 
AA4 3 CYS B 176 ? ASP B 180 ? CYS B 166 ASP B 170 
AA4 4 GLN B 186 ? PHE B 190 ? GLN B 176 PHE B 180 
AA5 1 VAL B 197 ? LEU B 202 ? VAL B 187 LEU B 192 
AA5 2 LEU B 208 ? ALA B 213 ? LEU B 198 ALA B 203 
AA5 3 ALA B 218 ? ASP B 222 ? ALA B 208 ASP B 212 
AA5 4 CYS B 228 ? PHE B 232 ? CYS B 218 PHE B 222 
AA6 1 ILE B 239 ? PHE B 244 ? ILE B 229 PHE B 234 
AA6 2 ALA B 250 ? SER B 255 ? ALA B 240 SER B 245 
AA6 3 CYS B 260 ? ASP B 264 ? CYS B 250 ASP B 254 
AA6 4 GLN B 269 ? TYR B 274 ? GLN B 259 TYR B 264 
AA7 1 ILE B 283 ? SER B 287 ? ILE B 273 SER B 277 
AA7 2 LEU B 295 ? TYR B 299 ? LEU B 285 TYR B 289 
AA7 3 CYS B 304 ? TRP B 307 ? CYS B 294 TRP B 297 
AA7 4 ARG B 314 ? LEU B 318 ? ARG B 304 LEU B 308 
AA8 1 ILE C 207 ? VAL C 214 ? ILE C 207 VAL C 214 
AA8 2 VAL C 217 ? VAL C 224 ? VAL C 217 VAL C 224 
AA8 3 HIS C 41  ? LEU C 46  ? HIS C 41  LEU C 46  
AA8 4 ALA C 243 ? ALA C 249 ? ALA C 243 ALA C 249 
AA8 5 SER C 286 ? ASN C 292 ? SER C 286 ASN C 292 
AA8 6 CYS C 359 ? HIS C 362 ? CYS C 359 HIS C 362 
AA9 1 GLN E 3   ? GLU E 6   ? GLN N 3   GLU N 6   
AA9 2 SER E 21  ? SER E 25  ? SER N 21  SER N 25  
AA9 3 THR E 78  ? MET E 83  ? THR N 78  MET N 83  
AA9 4 PHE E 68  ? ASP E 73  ? PHE N 68  ASP N 73  
AB1 1 LEU E 11  ? VAL E 12  ? LEU N 11  VAL N 12  
AB1 2 THR E 122 ? VAL E 126 ? THR N 122 VAL N 126 
AB1 3 ALA E 92  ? TYR E 95  ? ALA N 92  TYR N 95  
AB1 4 ASN E 35  ? GLN E 39  ? ASN N 35  GLN N 39  
AB1 5 LEU E 45  ? ILE E 51  ? LEU N 45  ILE N 51  
AB1 6 ILE E 58  ? TYR E 60  ? ILE N 58  TYR N 60  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG B 58  ? N ARG B 48  O ILE B 348 ? O ILE B 338 
AA1 2 3 O TRP B 349 ? O TRP B 339 N VAL B 337 ? N VAL B 327 
AA1 3 4 O GLY B 340 ? O GLY B 330 N CYS B 327 ? N CYS B 317 
AA2 1 2 N HIS B 72  ? N HIS B 62  O VAL B 81  ? O VAL B 71  
AA2 2 3 N LEU B 80  ? N LEU B 70  O TRP B 92  ? O TRP B 82  
AA2 3 4 N ASP B 93  ? N ASP B 83  O ASN B 98  ? O ASN B 88  
AA3 1 2 N ALA B 114 ? N ALA B 104 O ALA B 123 ? O ALA B 113 
AA3 2 3 N VAL B 122 ? N VAL B 112 O TYR B 134 ? O TYR B 124 
AA3 3 4 N ILE B 133 ? N ILE B 123 O SER B 146 ? O SER B 136 
AA4 1 2 N CYS B 158 ? N CYS B 148 O SER B 170 ? O SER B 160 
AA4 2 3 N ILE B 167 ? N ILE B 157 O TRP B 179 ? O TRP B 169 
AA4 3 4 N CYS B 176 ? N CYS B 166 O PHE B 190 ? O PHE B 180 
AA5 1 2 N SER B 199 ? N SER B 189 O GLY B 212 ? O GLY B 202 
AA5 2 3 N PHE B 209 ? N PHE B 199 O TRP B 221 ? O TRP B 211 
AA5 3 4 N LEU B 220 ? N LEU B 210 O ARG B 229 ? O ARG B 219 
AA6 1 2 N ASN B 240 ? N ASN B 230 O GLY B 254 ? O GLY B 244 
AA6 2 3 N PHE B 251 ? N PHE B 241 O PHE B 263 ? O PHE B 253 
AA6 3 4 N LEU B 262 ? N LEU B 252 O LEU B 271 ? O LEU B 261 
AA7 1 2 N SER B 287 ? N SER B 277 O LEU B 296 ? O LEU B 286 
AA7 2 3 N LEU B 295 ? N LEU B 285 O TRP B 307 ? O TRP B 297 
AA7 3 4 N CYS B 304 ? N CYS B 294 O LEU B 318 ? O LEU B 308 
AA8 1 2 N PHE C 208 ? N PHE C 208 O ASP C 223 ? O ASP C 223 
AA8 2 3 O HIS C 220 ? O HIS C 220 N HIS C 41  ? N HIS C 41  
AA8 3 4 N LEU C 44  ? N LEU C 44  O ILE C 245 ? O ILE C 245 
AA8 4 5 N PHE C 246 ? N PHE C 246 O ILE C 288 ? O ILE C 288 
AA8 5 6 N LEU C 289 ? N LEU C 289 O HIS C 362 ? O HIS C 362 
AA9 1 2 N GLN E 5   ? N GLN N 5   O ALA E 23  ? O ALA N 23  
AA9 2 3 N CYS E 22  ? N CYS N 22  O LEU E 79  ? O LEU N 79  
AA9 3 4 O THR E 78  ? O THR N 78  N ASP E 73  ? N ASP N 73  
AB1 1 2 N VAL E 12  ? N VAL N 12  O THR E 125 ? O THR N 125 
AB1 2 3 O THR E 122 ? O THR N 122 N TYR E 94  ? N TYR N 94  
AB1 3 4 O TYR E 95  ? O TYR N 95  N VAL E 37  ? N VAL N 37  
AB1 4 5 N TRP E 36  ? N TRP N 36  O VAL E 48  ? O VAL N 48  
AB1 5 6 N ASP E 50  ? N ASP N 50  O SER E 59  ? O SER N 59  
# 
_pdbx_entry_details.entry_id                   8TYW 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_1             C 
_pdbx_validate_rmsd_angle.auth_comp_id_1             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_1              223 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CG 
_pdbx_validate_rmsd_angle.auth_asym_id_2             C 
_pdbx_validate_rmsd_angle.auth_comp_id_2             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_2              223 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             OD1 
_pdbx_validate_rmsd_angle.auth_asym_id_3             C 
_pdbx_validate_rmsd_angle.auth_comp_id_3             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_3              223 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                125.10 
_pdbx_validate_rmsd_angle.angle_target_value         118.30 
_pdbx_validate_rmsd_angle.angle_deviation            6.80 
_pdbx_validate_rmsd_angle.angle_standard_deviation   0.90 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TRP A 207 ? ? -90.96  51.26   
2  1 LEU A 210 ? ? -120.29 -54.99  
3  1 ALA A 215 ? ? -95.80  58.15   
4  1 THR B 128 ? ? 66.18   162.43  
5  1 ASN B 132 ? ? 59.07   -161.94 
6  1 SER B 147 ? ? -121.74 -50.00  
7  1 MET B 188 ? ? -107.32 -63.87  
8  1 LEU B 261 ? ? -90.30  -62.14  
9  1 ASP B 291 ? ? -90.34  54.45   
10 1 ALA B 299 ? ? 65.51   -2.99   
11 1 ASN B 313 ? ? -147.60 -159.61 
12 1 LEU C 291 ? ? -100.00 77.70   
13 1 GLU G 47  ? ? -99.59  32.87   
14 1 TYR N 32  ? ? 60.75   70.10   
15 1 VAL N 48  ? ? -108.37 -62.78  
16 1 PHE N 103 ? ? 34.26   47.90   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8TYW 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8TYW 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.43 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               155135 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'GPR6-Gs-Nb35 complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8TYW 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8TYW 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8TYW 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ASN 2   ? A ASN 2   
3   1 Y 1 A ALA 3   ? A ALA 3   
4   1 Y 1 A SER 4   ? A SER 4   
5   1 Y 1 A ALA 5   ? A ALA 5   
6   1 Y 1 A ALA 6   ? A ALA 6   
7   1 Y 1 A SER 7   ? A SER 7   
8   1 Y 1 A LEU 8   ? A LEU 8   
9   1 Y 1 A ASN 9   ? A ASN 9   
10  1 Y 1 A ASP 10  ? A ASP 10  
11  1 Y 1 A SER 11  ? A SER 11  
12  1 Y 1 A GLN 12  ? A GLN 12  
13  1 Y 1 A VAL 13  ? A VAL 13  
14  1 Y 1 A VAL 14  ? A VAL 14  
15  1 Y 1 A VAL 15  ? A VAL 15  
16  1 Y 1 A VAL 16  ? A VAL 16  
17  1 Y 1 A ALA 17  ? A ALA 17  
18  1 Y 1 A ALA 18  ? A ALA 18  
19  1 Y 1 A GLU 19  ? A GLU 19  
20  1 Y 1 A GLY 20  ? A GLY 20  
21  1 Y 1 A ALA 21  ? A ALA 21  
22  1 Y 1 A ALA 22  ? A ALA 22  
23  1 Y 1 A ALA 23  ? A ALA 23  
24  1 Y 1 A ALA 24  ? A ALA 24  
25  1 Y 1 A ALA 25  ? A ALA 25  
26  1 Y 1 A THR 26  ? A THR 26  
27  1 Y 1 A ALA 27  ? A ALA 27  
28  1 Y 1 A ALA 28  ? A ALA 28  
29  1 Y 1 A GLY 29  ? A GLY 29  
30  1 Y 1 A GLY 30  ? A GLY 30  
31  1 Y 1 A PRO 31  ? A PRO 31  
32  1 Y 1 A ASP 32  ? A ASP 32  
33  1 Y 1 A THR 33  ? A THR 33  
34  1 Y 1 A GLY 34  ? A GLY 34  
35  1 Y 1 A GLU 35  ? A GLU 35  
36  1 Y 1 A TRP 36  ? A TRP 36  
37  1 Y 1 A GLY 37  ? A GLY 37  
38  1 Y 1 A PRO 38  ? A PRO 38  
39  1 Y 1 A PRO 39  ? A PRO 39  
40  1 Y 1 A ALA 40  ? A ALA 40  
41  1 Y 1 A ALA 41  ? A ALA 41  
42  1 Y 1 A ALA 42  ? A ALA 42  
43  1 Y 1 A ALA 43  ? A ALA 43  
44  1 Y 1 A LEU 44  ? A LEU 44  
45  1 Y 1 A GLY 45  ? A GLY 45  
46  1 Y 1 A ALA 46  ? A ALA 46  
47  1 Y 1 A GLY 47  ? A GLY 47  
48  1 Y 1 A GLY 48  ? A GLY 48  
49  1 Y 1 A GLY 49  ? A GLY 49  
50  1 Y 1 A ALA 50  ? A ALA 50  
51  1 Y 1 A ASN 51  ? A ASN 51  
52  1 Y 1 A GLY 52  ? A GLY 52  
53  1 Y 1 A SER 53  ? A SER 53  
54  1 Y 1 A LEU 54  ? A LEU 54  
55  1 Y 1 A GLU 55  ? A GLU 55  
56  1 Y 1 A LEU 56  ? A LEU 56  
57  1 Y 1 A SER 57  ? A SER 57  
58  1 Y 1 A SER 58  ? A SER 58  
59  1 Y 1 A GLN 59  ? A GLN 59  
60  1 Y 1 A LEU 60  ? A LEU 60  
61  1 Y 1 A SER 61  ? A SER 61  
62  1 Y 1 A ALA 62  ? A ALA 62  
63  1 Y 1 A GLY 63  ? A GLY 63  
64  1 Y 1 A PRO 64  ? A PRO 64  
65  1 Y 1 A PRO 65  ? A PRO 65  
66  1 Y 1 A GLY 66  ? A GLY 66  
67  1 Y 1 A LEU 67  ? A LEU 67  
68  1 Y 1 A LEU 68  ? A LEU 68  
69  1 Y 1 A LEU 69  ? A LEU 69  
70  1 Y 1 A PRO 70  ? A PRO 70  
71  1 Y 1 A ALA 71  ? A ALA 71  
72  1 Y 1 A CYS 265 ? A CYS 265 
73  1 Y 1 A LEU 266 ? A LEU 266 
74  1 Y 1 A ALA 267 ? A ALA 267 
75  1 Y 1 A PRO 268 ? A PRO 268 
76  1 Y 1 A PRO 269 ? A PRO 269 
77  1 Y 1 A HIS 270 ? A HIS 270 
78  1 Y 1 A LEU 271 ? A LEU 271 
79  1 Y 1 A ALA 272 ? A ALA 272 
80  1 Y 1 A ALA 273 ? A ALA 273 
81  1 Y 1 A CYS 345 ? A CYS 345 
82  1 Y 1 A GLY 346 ? A GLY 346 
83  1 Y 1 A CYS 347 ? A CYS 347 
84  1 Y 1 A PHE 348 ? A PHE 348 
85  1 Y 1 A GLN 349 ? A GLN 349 
86  1 Y 1 A SER 350 ? A SER 350 
87  1 Y 1 A LYS 351 ? A LYS 351 
88  1 Y 1 A VAL 352 ? A VAL 352 
89  1 Y 1 A PRO 353 ? A PRO 353 
90  1 Y 1 A PHE 354 ? A PHE 354 
91  1 Y 1 A ARG 355 ? A ARG 355 
92  1 Y 1 A SER 356 ? A SER 356 
93  1 Y 1 A ARG 357 ? A ARG 357 
94  1 Y 1 A SER 358 ? A SER 358 
95  1 Y 1 A PRO 359 ? A PRO 359 
96  1 Y 1 A SER 360 ? A SER 360 
97  1 Y 1 A GLU 361 ? A GLU 361 
98  1 Y 1 A VAL 362 ? A VAL 362 
99  1 Y 1 A HIS 363 ? A HIS 363 
100 1 Y 1 A HIS 364 ? A HIS 364 
101 1 Y 1 A HIS 365 ? A HIS 365 
102 1 Y 1 A HIS 366 ? A HIS 366 
103 1 Y 1 A HIS 367 ? A HIS 367 
104 1 Y 1 A HIS 368 ? A HIS 368 
105 1 Y 1 A HIS 369 ? A HIS 369 
106 1 Y 1 A HIS 370 ? A HIS 370 
107 1 Y 1 A HIS 371 ? A HIS 371 
108 1 Y 1 A HIS 372 ? A HIS 372 
109 1 Y 1 B MET -9  ? B MET 1   
110 1 Y 1 B HIS -8  ? B HIS 2   
111 1 Y 1 B HIS -7  ? B HIS 3   
112 1 Y 1 B HIS -6  ? B HIS 4   
113 1 Y 1 B HIS -5  ? B HIS 5   
114 1 Y 1 B HIS -4  ? B HIS 6   
115 1 Y 1 B HIS -3  ? B HIS 7   
116 1 Y 1 B GLY -2  ? B GLY 8   
117 1 Y 1 B SER -1  ? B SER 9   
118 1 Y 1 B SER 0   ? B SER 10  
119 1 Y 1 B GLY 1   ? B GLY 11  
120 1 Y 1 C MET 1   ? C MET 1   
121 1 Y 1 C GLY 2   ? C GLY 2   
122 1 Y 1 C CYS 3   ? C CYS 3   
123 1 Y 1 C LEU 4   ? C LEU 4   
124 1 Y 1 C GLY 5   ? C GLY 5   
125 1 Y 1 C ASN 6   ? C ASN 6   
126 1 Y 1 C SER 7   ? C SER 7   
127 1 Y 1 C ALA 48  ? C ALA 48  
128 1 Y 1 C GLY 49  ? C GLY 49  
129 1 Y 1 C GLU 50  ? C GLU 50  
130 1 Y 1 C VAL 65  ? C VAL 65  
131 1 Y 1 C ASN 66  ? C ASN 66  
132 1 Y 1 C GLY 67  ? C GLY 67  
133 1 Y 1 C PHE 68  ? C PHE 68  
134 1 Y 1 C ASN 69  ? C ASN 69  
135 1 Y 1 C GLY 70  ? C GLY 70  
136 1 Y 1 C GLU 71  ? C GLU 71  
137 1 Y 1 C GLY 72  ? C GLY 72  
138 1 Y 1 C GLY 73  ? C GLY 73  
139 1 Y 1 C GLU 74  ? C GLU 74  
140 1 Y 1 C GLU 75  ? C GLU 75  
141 1 Y 1 C ASP 76  ? C ASP 76  
142 1 Y 1 C PRO 77  ? C PRO 77  
143 1 Y 1 C GLN 78  ? C GLN 78  
144 1 Y 1 C ALA 79  ? C ALA 79  
145 1 Y 1 C ALA 80  ? C ALA 80  
146 1 Y 1 C ARG 81  ? C ARG 81  
147 1 Y 1 C SER 82  ? C SER 82  
148 1 Y 1 C ASN 83  ? C ASN 83  
149 1 Y 1 C SER 84  ? C SER 84  
150 1 Y 1 C ASP 85  ? C ASP 85  
151 1 Y 1 C GLY 86  ? C GLY 86  
152 1 Y 1 C GLU 87  ? C GLU 87  
153 1 Y 1 C LYS 88  ? C LYS 88  
154 1 Y 1 C ALA 89  ? C ALA 89  
155 1 Y 1 C THR 90  ? C THR 90  
156 1 Y 1 C LYS 91  ? C LYS 91  
157 1 Y 1 C VAL 92  ? C VAL 92  
158 1 Y 1 C GLN 93  ? C GLN 93  
159 1 Y 1 C ASP 94  ? C ASP 94  
160 1 Y 1 C ILE 95  ? C ILE 95  
161 1 Y 1 C LYS 96  ? C LYS 96  
162 1 Y 1 C ASN 97  ? C ASN 97  
163 1 Y 1 C ASN 98  ? C ASN 98  
164 1 Y 1 C LEU 99  ? C LEU 99  
165 1 Y 1 C LYS 100 ? C LYS 100 
166 1 Y 1 C GLU 101 ? C GLU 101 
167 1 Y 1 C ALA 102 ? C ALA 102 
168 1 Y 1 C ILE 103 ? C ILE 103 
169 1 Y 1 C GLU 104 ? C GLU 104 
170 1 Y 1 C THR 105 ? C THR 105 
171 1 Y 1 C ILE 106 ? C ILE 106 
172 1 Y 1 C VAL 107 ? C VAL 107 
173 1 Y 1 C ALA 108 ? C ALA 108 
174 1 Y 1 C ALA 109 ? C ALA 109 
175 1 Y 1 C MET 110 ? C MET 110 
176 1 Y 1 C SER 111 ? C SER 111 
177 1 Y 1 C ASN 112 ? C ASN 112 
178 1 Y 1 C LEU 113 ? C LEU 113 
179 1 Y 1 C VAL 114 ? C VAL 114 
180 1 Y 1 C PRO 115 ? C PRO 115 
181 1 Y 1 C PRO 116 ? C PRO 116 
182 1 Y 1 C VAL 117 ? C VAL 117 
183 1 Y 1 C GLU 118 ? C GLU 118 
184 1 Y 1 C LEU 119 ? C LEU 119 
185 1 Y 1 C ALA 120 ? C ALA 120 
186 1 Y 1 C ASN 121 ? C ASN 121 
187 1 Y 1 C PRO 122 ? C PRO 122 
188 1 Y 1 C GLU 123 ? C GLU 123 
189 1 Y 1 C ASN 124 ? C ASN 124 
190 1 Y 1 C GLN 125 ? C GLN 125 
191 1 Y 1 C PHE 126 ? C PHE 126 
192 1 Y 1 C ARG 127 ? C ARG 127 
193 1 Y 1 C VAL 128 ? C VAL 128 
194 1 Y 1 C ASP 129 ? C ASP 129 
195 1 Y 1 C TYR 130 ? C TYR 130 
196 1 Y 1 C ILE 131 ? C ILE 131 
197 1 Y 1 C LEU 132 ? C LEU 132 
198 1 Y 1 C SER 133 ? C SER 133 
199 1 Y 1 C VAL 134 ? C VAL 134 
200 1 Y 1 C MET 135 ? C MET 135 
201 1 Y 1 C ASN 136 ? C ASN 136 
202 1 Y 1 C VAL 137 ? C VAL 137 
203 1 Y 1 C PRO 138 ? C PRO 138 
204 1 Y 1 C ASP 139 ? C ASP 139 
205 1 Y 1 C PHE 140 ? C PHE 140 
206 1 Y 1 C ASP 141 ? C ASP 141 
207 1 Y 1 C PHE 142 ? C PHE 142 
208 1 Y 1 C PRO 143 ? C PRO 143 
209 1 Y 1 C PRO 144 ? C PRO 144 
210 1 Y 1 C GLU 145 ? C GLU 145 
211 1 Y 1 C PHE 146 ? C PHE 146 
212 1 Y 1 C TYR 147 ? C TYR 147 
213 1 Y 1 C GLU 148 ? C GLU 148 
214 1 Y 1 C HIS 149 ? C HIS 149 
215 1 Y 1 C ALA 150 ? C ALA 150 
216 1 Y 1 C LYS 151 ? C LYS 151 
217 1 Y 1 C ALA 152 ? C ALA 152 
218 1 Y 1 C LEU 153 ? C LEU 153 
219 1 Y 1 C TRP 154 ? C TRP 154 
220 1 Y 1 C GLU 155 ? C GLU 155 
221 1 Y 1 C ASP 156 ? C ASP 156 
222 1 Y 1 C GLU 157 ? C GLU 157 
223 1 Y 1 C GLY 158 ? C GLY 158 
224 1 Y 1 C VAL 159 ? C VAL 159 
225 1 Y 1 C ARG 160 ? C ARG 160 
226 1 Y 1 C ALA 161 ? C ALA 161 
227 1 Y 1 C CYS 162 ? C CYS 162 
228 1 Y 1 C TYR 163 ? C TYR 163 
229 1 Y 1 C GLU 164 ? C GLU 164 
230 1 Y 1 C ARG 165 ? C ARG 165 
231 1 Y 1 C SER 166 ? C SER 166 
232 1 Y 1 C ASN 167 ? C ASN 167 
233 1 Y 1 C GLU 168 ? C GLU 168 
234 1 Y 1 C TYR 169 ? C TYR 169 
235 1 Y 1 C GLN 170 ? C GLN 170 
236 1 Y 1 C LEU 171 ? C LEU 171 
237 1 Y 1 C ILE 172 ? C ILE 172 
238 1 Y 1 C ASP 173 ? C ASP 173 
239 1 Y 1 C CYS 174 ? C CYS 174 
240 1 Y 1 C ALA 175 ? C ALA 175 
241 1 Y 1 C GLN 176 ? C GLN 176 
242 1 Y 1 C TYR 177 ? C TYR 177 
243 1 Y 1 C PHE 178 ? C PHE 178 
244 1 Y 1 C LEU 179 ? C LEU 179 
245 1 Y 1 C ASP 180 ? C ASP 180 
246 1 Y 1 C LYS 181 ? C LYS 181 
247 1 Y 1 C ILE 182 ? C ILE 182 
248 1 Y 1 C ASP 183 ? C ASP 183 
249 1 Y 1 C VAL 184 ? C VAL 184 
250 1 Y 1 C ILE 185 ? C ILE 185 
251 1 Y 1 C LYS 186 ? C LYS 186 
252 1 Y 1 C GLN 187 ? C GLN 187 
253 1 Y 1 C ALA 188 ? C ALA 188 
254 1 Y 1 C ASP 189 ? C ASP 189 
255 1 Y 1 C TYR 190 ? C TYR 190 
256 1 Y 1 C VAL 191 ? C VAL 191 
257 1 Y 1 C PRO 192 ? C PRO 192 
258 1 Y 1 C SER 193 ? C SER 193 
259 1 Y 1 C ASP 194 ? C ASP 194 
260 1 Y 1 C GLN 195 ? C GLN 195 
261 1 Y 1 C ASP 196 ? C ASP 196 
262 1 Y 1 C LEU 197 ? C LEU 197 
263 1 Y 1 C LEU 198 ? C LEU 198 
264 1 Y 1 C ARG 199 ? C ARG 199 
265 1 Y 1 C CYS 200 ? C CYS 200 
266 1 Y 1 C ARG 201 ? C ARG 201 
267 1 Y 1 C VAL 202 ? C VAL 202 
268 1 Y 1 C LEU 203 ? C LEU 203 
269 1 Y 1 C ASN 254 ? C ASN 254 
270 1 Y 1 C MET 255 ? C MET 255 
271 1 Y 1 C VAL 256 ? C VAL 256 
272 1 Y 1 C ILE 257 ? C ILE 257 
273 1 Y 1 C ARG 258 ? C ARG 258 
274 1 Y 1 C GLU 259 ? C GLU 259 
275 1 Y 1 C ASP 260 ? C ASP 260 
276 1 Y 1 C ASN 261 ? C ASN 261 
277 1 Y 1 G MET 1   ? D MET 1   
278 1 Y 1 G ALA 2   ? D ALA 2   
279 1 Y 1 G SER 3   ? D SER 3   
280 1 Y 1 G ASN 4   ? D ASN 4   
281 1 Y 1 G GLU 63  ? D GLU 63  
282 1 Y 1 G LYS 64  ? D LYS 64  
283 1 Y 1 G LYS 65  ? D LYS 65  
284 1 Y 1 G PHE 66  ? D PHE 66  
285 1 Y 1 G PHE 67  ? D PHE 67  
286 1 Y 1 G CYS 68  ? D CYS 68  
287 1 Y 1 G ALA 69  ? D ALA 69  
288 1 Y 1 G ILE 70  ? D ILE 70  
289 1 Y 1 G LEU 71  ? D LEU 71  
290 1 Y 1 N HIS 129 ? E HIS 129 
291 1 Y 1 N HIS 130 ? E HIS 130 
292 1 Y 1 N HIS 131 ? E HIS 131 
293 1 Y 1 N HIS 132 ? E HIS 132 
294 1 Y 1 N HIS 133 ? E HIS 133 
295 1 Y 1 N HIS 134 ? E HIS 134 
296 1 Y 1 N GLU 135 ? E GLU 135 
297 1 Y 1 N PRO 136 ? E PRO 136 
298 1 Y 1 N GLU 137 ? E GLU 137 
299 1 Y 1 N ALA 138 ? E ALA 138 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-26 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8TYW 
_em_admin.last_update        2025-01-08 
_em_admin.map_release_date   2024-12-04 
_em_admin.title              'cryo-EM structure of GPR6-Gs-Nb35 complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           'R35 GM127086' 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8TYW 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . VAL A 1 72  ? 149.858 116.092 89.202  1.00 124.48 ? 72  VAL A N   1 
ATOM 2    C CA  . VAL A 1 72  ? 148.551 116.025 89.843  1.00 124.95 ? 72  VAL A CA  1 
ATOM 3    C C   . VAL A 1 72  ? 148.096 117.424 90.240  1.00 124.48 ? 72  VAL A C   1 
ATOM 4    O O   . VAL A 1 72  ? 148.909 118.343 90.343  1.00 125.03 ? 72  VAL A O   1 
ATOM 5    C CB  . VAL A 1 72  ? 148.578 115.088 91.063  1.00 124.95 ? 72  VAL A CB  1 
ATOM 6    C CG1 . VAL A 1 72  ? 148.894 113.664 90.629  1.00 125.87 ? 72  VAL A CG1 1 
ATOM 7    C CG2 . VAL A 1 72  ? 149.591 115.575 92.089  1.00 123.12 ? 72  VAL A CG2 1 
ATOM 8    N N   . ASN A 1 73  ? 146.793 117.586 90.458  1.00 118.17 ? 73  ASN A N   1 
ATOM 9    C CA  . ASN A 1 73  ? 146.243 118.882 90.828  1.00 111.19 ? 73  ASN A CA  1 
ATOM 10   C C   . ASN A 1 73  ? 146.210 119.010 92.344  1.00 109.77 ? 73  ASN A C   1 
ATOM 11   O O   . ASN A 1 73  ? 145.546 118.203 93.006  1.00 109.81 ? 73  ASN A O   1 
ATOM 12   C CB  . ASN A 1 73  ? 144.847 119.055 90.264  1.00 109.16 ? 73  ASN A CB  1 
ATOM 13   C CG  . ASN A 1 73  ? 144.561 120.486 89.863  1.00 113.48 ? 73  ASN A CG  1 
ATOM 14   O OD1 . ASN A 1 73  ? 144.764 121.412 90.647  1.00 112.97 ? 73  ASN A OD1 1 
ATOM 15   N ND2 . ASN A 1 73  ? 144.085 120.675 88.638  1.00 114.35 ? 73  ASN A ND2 1 
ATOM 16   N N   . PRO A 1 74  ? 146.900 119.993 92.930  1.00 111.23 ? 74  PRO A N   1 
ATOM 17   C CA  . PRO A 1 74  ? 146.917 120.107 94.399  1.00 112.39 ? 74  PRO A CA  1 
ATOM 18   C C   . PRO A 1 74  ? 145.585 120.522 94.999  1.00 109.68 ? 74  PRO A C   1 
ATOM 19   O O   . PRO A 1 74  ? 145.387 120.333 96.208  1.00 111.31 ? 74  PRO A O   1 
ATOM 20   C CB  . PRO A 1 74  ? 147.997 121.166 94.657  1.00 115.77 ? 74  PRO A CB  1 
ATOM 21   C CG  . PRO A 1 74  ? 148.034 121.976 93.402  1.00 115.31 ? 74  PRO A CG  1 
ATOM 22   C CD  . PRO A 1 74  ? 147.721 121.028 92.279  1.00 114.49 ? 74  PRO A CD  1 
ATOM 23   N N   . TRP A 1 75  ? 144.676 121.084 94.198  1.00 107.00 ? 75  TRP A N   1 
ATOM 24   C CA  . TRP A 1 75  ? 143.358 121.442 94.708  1.00 108.06 ? 75  TRP A CA  1 
ATOM 25   C C   . TRP A 1 75  ? 142.589 120.208 95.154  1.00 106.50 ? 75  TRP A C   1 
ATOM 26   O O   . TRP A 1 75  ? 141.883 120.240 96.170  1.00 108.74 ? 75  TRP A O   1 
ATOM 27   C CB  . TRP A 1 75  ? 142.570 122.207 93.644  1.00 106.23 ? 75  TRP A CB  1 
ATOM 28   C CG  . TRP A 1 75  ? 143.130 123.553 93.326  1.00 108.00 ? 75  TRP A CG  1 
ATOM 29   C CD1 . TRP A 1 75  ? 143.737 123.933 92.168  1.00 106.21 ? 75  TRP A CD1 1 
ATOM 30   C CD2 . TRP A 1 75  ? 143.128 124.706 94.176  1.00 112.29 ? 75  TRP A CD2 1 
ATOM 31   N NE1 . TRP A 1 75  ? 144.119 125.251 92.243  1.00 110.27 ? 75  TRP A NE1 1 
ATOM 32   C CE2 . TRP A 1 75  ? 143.756 125.748 93.466  1.00 112.88 ? 75  TRP A CE2 1 
ATOM 33   C CE3 . TRP A 1 75  ? 142.660 124.957 95.469  1.00 111.68 ? 75  TRP A CE3 1 
ATOM 34   C CZ2 . TRP A 1 75  ? 143.927 127.021 94.006  1.00 111.77 ? 75  TRP A CZ2 1 
ATOM 35   C CZ3 . TRP A 1 75  ? 142.830 126.222 96.003  1.00 112.68 ? 75  TRP A CZ3 1 
ATOM 36   C CH2 . TRP A 1 75  ? 143.458 127.238 95.272  1.00 114.27 ? 75  TRP A CH2 1 
ATOM 37   N N   . ASP A 1 76  ? 142.730 119.108 94.414  1.00 103.26 ? 76  ASP A N   1 
ATOM 38   C CA  . ASP A 1 76  ? 142.022 117.883 94.761  1.00 108.28 ? 76  ASP A CA  1 
ATOM 39   C C   . ASP A 1 76  ? 142.529 117.294 96.071  1.00 108.94 ? 76  ASP A C   1 
ATOM 40   O O   . ASP A 1 76  ? 141.734 116.836 96.898  1.00 111.06 ? 76  ASP A O   1 
ATOM 41   C CB  . ASP A 1 76  ? 142.143 116.876 93.620  1.00 116.37 ? 76  ASP A CB  1 
ATOM 42   C CG  . ASP A 1 76  ? 141.706 117.457 92.290  1.00 118.67 ? 76  ASP A CG  1 
ATOM 43   O OD1 . ASP A 1 76  ? 141.339 118.651 92.257  1.00 114.67 ? 76  ASP A OD1 1 
ATOM 44   O OD2 . ASP A 1 76  ? 141.720 116.726 91.280  1.00 119.44 ? 76  ASP A OD2 1 
ATOM 45   N N   . VAL A 1 77  ? 143.843 117.316 96.293  1.00 109.28 ? 77  VAL A N   1 
ATOM 46   C CA  . VAL A 1 77  ? 144.351 116.768 97.546  1.00 112.99 ? 77  VAL A CA  1 
ATOM 47   C C   . VAL A 1 77  ? 144.069 117.718 98.711  1.00 110.31 ? 77  VAL A C   1 
ATOM 48   O O   . VAL A 1 77  ? 143.885 117.263 99.851  1.00 112.38 ? 77  VAL A O   1 
ATOM 49   C CB  . VAL A 1 77  ? 145.847 116.403 97.416  1.00 113.26 ? 77  VAL A CB  1 
ATOM 50   C CG1 . VAL A 1 77  ? 146.760 117.624 97.490  1.00 112.75 ? 77  VAL A CG1 1 
ATOM 51   C CG2 . VAL A 1 77  ? 146.239 115.372 98.468  1.00 112.88 ? 77  VAL A CG2 1 
ATOM 52   N N   . LEU A 1 78  ? 143.983 119.030 98.449  1.00 106.28 ? 78  LEU A N   1 
ATOM 53   C CA  . LEU A 1 78  ? 143.568 119.965 99.490  1.00 106.48 ? 78  LEU A CA  1 
ATOM 54   C C   . LEU A 1 78  ? 142.123 119.702 99.896  1.00 110.14 ? 78  LEU A C   1 
ATOM 55   O O   . LEU A 1 78  ? 141.798 119.676 101.090 1.00 112.97 ? 78  LEU A O   1 
ATOM 56   C CB  . LEU A 1 78  ? 143.746 121.402 98.995  1.00 106.25 ? 78  LEU A CB  1 
ATOM 57   C CG  . LEU A 1 78  ? 143.240 122.655 99.729  1.00 106.91 ? 78  LEU A CG  1 
ATOM 58   C CD1 . LEU A 1 78  ? 143.371 122.584 101.254 1.00 106.78 ? 78  LEU A CD1 1 
ATOM 59   C CD2 . LEU A 1 78  ? 143.943 123.896 99.191  1.00 103.11 ? 78  LEU A CD2 1 
ATOM 60   N N   . LEU A 1 79  ? 141.253 119.467 98.913  1.00 109.55 ? 79  LEU A N   1 
ATOM 61   C CA  . LEU A 1 79  ? 139.870 119.123 99.216  1.00 110.55 ? 79  LEU A CA  1 
ATOM 62   C C   . LEU A 1 79  ? 139.764 117.767 99.903  1.00 108.50 ? 79  LEU A C   1 
ATOM 63   O O   . LEU A 1 79  ? 138.886 117.574 100.746 1.00 108.25 ? 79  LEU A O   1 
ATOM 64   C CB  . LEU A 1 79  ? 139.034 119.147 97.940  1.00 108.92 ? 79  LEU A CB  1 
ATOM 65   C CG  . LEU A 1 79  ? 138.796 120.543 97.365  1.00 105.89 ? 79  LEU A CG  1 
ATOM 66   C CD1 . LEU A 1 79  ? 138.279 120.458 95.940  1.00 101.41 ? 79  LEU A CD1 1 
ATOM 67   C CD2 . LEU A 1 79  ? 137.836 121.323 98.245  1.00 103.38 ? 79  LEU A CD2 1 
ATOM 68   N N   . CYS A 1 80  ? 140.656 116.832 99.573  1.00 108.84 ? 80  CYS A N   1 
ATOM 69   C CA  . CYS A 1 80  ? 140.635 115.521 100.215 1.00 113.10 ? 80  CYS A CA  1 
ATOM 70   C C   . CYS A 1 80  ? 141.007 115.615 101.693 1.00 115.99 ? 80  CYS A C   1 
ATOM 71   O O   . CYS A 1 80  ? 140.329 115.030 102.549 1.00 116.91 ? 80  CYS A O   1 
ATOM 72   C CB  . CYS A 1 80  ? 141.575 114.564 99.481  1.00 116.64 ? 80  CYS A CB  1 
ATOM 73   S SG  . CYS A 1 80  ? 142.041 113.098 100.432 1.00 125.90 ? 80  CYS A SG  1 
ATOM 74   N N   . VAL A 1 81  ? 142.078 116.349 102.015 1.00 115.51 ? 81  VAL A N   1 
ATOM 75   C CA  . VAL A 1 81  ? 142.457 116.469 103.423 1.00 113.63 ? 81  VAL A CA  1 
ATOM 76   C C   . VAL A 1 81  ? 141.438 117.315 104.183 1.00 112.41 ? 81  VAL A C   1 
ATOM 77   O O   . VAL A 1 81  ? 141.164 117.053 105.370 1.00 110.95 ? 81  VAL A O   1 
ATOM 78   C CB  . VAL A 1 81  ? 143.899 117.000 103.582 1.00 112.79 ? 81  VAL A CB  1 
ATOM 79   C CG1 . VAL A 1 81  ? 144.892 116.017 102.973 1.00 112.98 ? 81  VAL A CG1 1 
ATOM 80   C CG2 . VAL A 1 81  ? 144.075 118.380 102.975 1.00 111.55 ? 81  VAL A CG2 1 
ATOM 81   N N   . SER A 1 82  ? 140.810 118.286 103.507 1.00 112.83 ? 82  SER A N   1 
ATOM 82   C CA  . SER A 1 82  ? 139.692 119.000 104.111 1.00 112.53 ? 82  SER A CA  1 
ATOM 83   C C   . SER A 1 82  ? 138.565 118.039 104.460 1.00 115.55 ? 82  SER A C   1 
ATOM 84   O O   . SER A 1 82  ? 138.174 117.943 105.627 1.00 116.35 ? 82  SER A O   1 
ATOM 85   C CB  . SER A 1 82  ? 139.191 120.091 103.169 1.00 109.03 ? 82  SER A CB  1 
ATOM 86   O OG  . SER A 1 82  ? 138.384 119.539 102.149 1.00 109.82 ? 82  SER A OG  1 
ATOM 87   N N   . GLY A 1 83  ? 138.130 117.233 103.484 1.00 116.72 ? 83  GLY A N   1 
ATOM 88   C CA  . GLY A 1 83  ? 137.021 116.316 103.703 1.00 111.68 ? 83  GLY A CA  1 
ATOM 89   C C   . GLY A 1 83  ? 137.298 115.294 104.785 1.00 111.73 ? 83  GLY A C   1 
ATOM 90   O O   . GLY A 1 83  ? 136.393 114.910 105.530 1.00 113.57 ? 83  GLY A O   1 
ATOM 91   N N   . THR A 1 84  ? 138.561 114.874 104.918 1.00 111.91 ? 84  THR A N   1 
ATOM 92   C CA  . THR A 1 84  ? 138.933 114.064 106.074 1.00 114.57 ? 84  THR A CA  1 
ATOM 93   C C   . THR A 1 84  ? 138.758 114.842 107.374 1.00 113.73 ? 84  THR A C   1 
ATOM 94   O O   . THR A 1 84  ? 138.346 114.269 108.393 1.00 115.24 ? 84  THR A O   1 
ATOM 95   C CB  . THR A 1 84  ? 140.371 113.558 105.959 1.00 116.81 ? 84  THR A CB  1 
ATOM 96   O OG1 . THR A 1 84  ? 141.269 114.666 105.850 1.00 118.53 ? 84  THR A OG1 1 
ATOM 97   C CG2 . THR A 1 84  ? 140.533 112.633 104.761 1.00 114.38 ? 84  THR A CG2 1 
ATOM 98   N N   . VAL A 1 85  ? 139.059 116.147 107.362 1.00 110.91 ? 85  VAL A N   1 
ATOM 99   C CA  . VAL A 1 85  ? 138.915 116.938 108.586 1.00 109.64 ? 85  VAL A CA  1 
ATOM 100  C C   . VAL A 1 85  ? 137.442 117.062 108.992 1.00 108.00 ? 85  VAL A C   1 
ATOM 101  O O   . VAL A 1 85  ? 137.099 116.862 110.166 1.00 107.26 ? 85  VAL A O   1 
ATOM 102  C CB  . VAL A 1 85  ? 139.601 118.311 108.434 1.00 112.92 ? 85  VAL A CB  1 
ATOM 103  C CG1 . VAL A 1 85  ? 138.947 119.368 109.310 1.00 108.56 ? 85  VAL A CG1 1 
ATOM 104  C CG2 . VAL A 1 85  ? 141.087 118.198 108.750 1.00 113.27 ? 85  VAL A CG2 1 
ATOM 105  N N   . ILE A 1 86  ? 136.546 117.366 108.034 1.00 108.84 ? 86  ILE A N   1 
ATOM 106  C CA  . ILE A 1 86  ? 135.122 117.422 108.405 1.00 106.62 ? 86  ILE A CA  1 
ATOM 107  C C   . ILE A 1 86  ? 134.601 116.036 108.786 1.00 106.51 ? 86  ILE A C   1 
ATOM 108  O O   . ILE A 1 86  ? 133.765 115.910 109.694 1.00 105.95 ? 86  ILE A O   1 
ATOM 109  C CB  . ILE A 1 86  ? 134.172 118.090 107.371 1.00 101.79 ? 86  ILE A CB  1 
ATOM 110  C CG1 . ILE A 1 86  ? 134.665 119.362 106.661 1.00 103.47 ? 86  ILE A CG1 1 
ATOM 111  C CG2 . ILE A 1 86  ? 132.848 118.445 107.999 1.00 101.73 ? 86  ILE A CG2 1 
ATOM 112  C CD1 . ILE A 1 86  ? 135.414 119.199 105.435 1.00 104.89 ? 86  ILE A CD1 1 
ATOM 113  N N   . ALA A 1 87  ? 135.093 114.979 108.127 1.00 110.17 ? 87  ALA A N   1 
ATOM 114  C CA  . ALA A 1 87  ? 134.669 113.627 108.483 1.00 112.61 ? 87  ALA A CA  1 
ATOM 115  C C   . ALA A 1 87  ? 135.026 113.300 109.926 1.00 115.85 ? 87  ALA A C   1 
ATOM 116  O O   . ALA A 1 87  ? 134.177 112.821 110.685 1.00 116.09 ? 87  ALA A O   1 
ATOM 117  C CB  . ALA A 1 87  ? 135.296 112.609 107.530 1.00 111.95 ? 87  ALA A CB  1 
ATOM 118  N N   . GLY A 1 88  ? 136.249 113.636 110.344 1.00 116.52 ? 88  GLY A N   1 
ATOM 119  C CA  . GLY A 1 88  ? 136.638 113.415 111.728 1.00 116.57 ? 88  GLY A CA  1 
ATOM 120  C C   . GLY A 1 88  ? 135.861 114.269 112.716 1.00 114.98 ? 88  GLY A C   1 
ATOM 121  O O   . GLY A 1 88  ? 135.434 113.780 113.770 1.00 119.73 ? 88  GLY A O   1 
ATOM 122  N N   . GLU A 1 89  ? 135.646 115.548 112.380 1.00 109.46 ? 89  GLU A N   1 
ATOM 123  C CA  . GLU A 1 89  ? 134.996 116.462 113.317 1.00 109.71 ? 89  GLU A CA  1 
ATOM 124  C C   . GLU A 1 89  ? 133.541 116.076 113.559 1.00 109.57 ? 89  GLU A C   1 
ATOM 125  O O   . GLU A 1 89  ? 133.107 115.934 114.709 1.00 110.51 ? 89  GLU A O   1 
ATOM 126  C CB  . GLU A 1 89  ? 135.095 117.899 112.806 1.00 112.39 ? 89  GLU A CB  1 
ATOM 127  C CG  . GLU A 1 89  ? 136.479 118.514 112.966 1.00 118.93 ? 89  GLU A CG  1 
ATOM 128  C CD  . GLU A 1 89  ? 136.845 118.763 114.418 1.00 123.78 ? 89  GLU A CD  1 
ATOM 129  O OE1 . GLU A 1 89  ? 136.150 119.560 115.082 1.00 121.28 ? 89  GLU A OE1 1 
ATOM 130  O OE2 . GLU A 1 89  ? 137.829 118.160 114.898 1.00 128.00 ? 89  GLU A OE2 1 
ATOM 131  N N   . ASN A 1 90  ? 132.775 115.864 112.492 1.00 107.84 ? 90  ASN A N   1 
ATOM 132  C CA  . ASN A 1 90  ? 131.403 115.422 112.703 1.00 107.52 ? 90  ASN A CA  1 
ATOM 133  C C   . ASN A 1 90  ? 131.280 113.955 113.077 1.00 106.96 ? 90  ASN A C   1 
ATOM 134  O O   . ASN A 1 90  ? 130.236 113.572 113.607 1.00 106.65 ? 90  ASN A O   1 
ATOM 135  C CB  . ASN A 1 90  ? 130.550 115.751 111.486 1.00 103.65 ? 90  ASN A CB  1 
ATOM 136  C CG  . ASN A 1 90  ? 130.759 117.160 111.024 1.00 101.23 ? 90  ASN A CG  1 
ATOM 137  O OD1 . ASN A 1 90  ? 131.884 117.621 110.902 1.00 105.18 ? 90  ASN A OD1 1 
ATOM 138  N ND2 . ASN A 1 90  ? 129.667 117.861 110.769 1.00 92.27  ? 90  ASN A ND2 1 
ATOM 139  N N   . ALA A 1 91  ? 132.316 113.136 112.875 1.00 111.55 ? 91  ALA A N   1 
ATOM 140  C CA  . ALA A 1 91  ? 132.314 111.821 113.503 1.00 117.51 ? 91  ALA A CA  1 
ATOM 141  C C   . ALA A 1 91  ? 132.365 111.954 115.016 1.00 116.22 ? 91  ALA A C   1 
ATOM 142  O O   . ALA A 1 91  ? 131.632 111.261 115.733 1.00 118.15 ? 91  ALA A O   1 
ATOM 143  C CB  . ALA A 1 91  ? 133.489 110.988 112.990 1.00 116.60 ? 91  ALA A CB  1 
ATOM 144  N N   . LEU A 1 92  ? 133.200 112.871 115.514 1.00 112.54 ? 92  LEU A N   1 
ATOM 145  C CA  . LEU A 1 92  ? 133.230 113.154 116.947 1.00 109.57 ? 92  LEU A CA  1 
ATOM 146  C C   . LEU A 1 92  ? 131.897 113.717 117.425 1.00 111.07 ? 92  LEU A C   1 
ATOM 147  O O   . LEU A 1 92  ? 131.411 113.353 118.505 1.00 116.54 ? 92  LEU A O   1 
ATOM 148  C CB  . LEU A 1 92  ? 134.388 114.108 117.261 1.00 109.78 ? 92  LEU A CB  1 
ATOM 149  C CG  . LEU A 1 92  ? 134.565 114.812 118.611 1.00 111.83 ? 92  LEU A CG  1 
ATOM 150  C CD1 . LEU A 1 92  ? 136.045 114.983 118.884 1.00 114.69 ? 92  LEU A CD1 1 
ATOM 151  C CD2 . LEU A 1 92  ? 133.906 116.185 118.638 1.00 109.46 ? 92  LEU A CD2 1 
ATOM 152  N N   . VAL A 1 93  ? 131.289 114.598 116.626 1.00 109.01 ? 93  VAL A N   1 
ATOM 153  C CA  . VAL A 1 93  ? 130.019 115.214 117.015 1.00 111.64 ? 93  VAL A CA  1 
ATOM 154  C C   . VAL A 1 93  ? 128.908 114.168 117.095 1.00 111.41 ? 93  VAL A C   1 
ATOM 155  O O   . VAL A 1 93  ? 128.144 114.123 118.069 1.00 114.40 ? 93  VAL A O   1 
ATOM 156  C CB  . VAL A 1 93  ? 129.657 116.357 116.049 1.00 109.36 ? 93  VAL A CB  1 
ATOM 157  C CG1 . VAL A 1 93  ? 128.248 116.857 116.312 1.00 102.42 ? 93  VAL A CG1 1 
ATOM 158  C CG2 . VAL A 1 93  ? 130.646 117.501 116.196 1.00 105.62 ? 93  VAL A CG2 1 
ATOM 159  N N   . VAL A 1 94  ? 128.813 113.297 116.086 1.00 109.20 ? 94  VAL A N   1 
ATOM 160  C CA  . VAL A 1 94  ? 127.758 112.289 116.098 1.00 106.68 ? 94  VAL A CA  1 
ATOM 161  C C   . VAL A 1 94  ? 128.036 111.225 117.155 1.00 108.86 ? 94  VAL A C   1 
ATOM 162  O O   . VAL A 1 94  ? 127.097 110.655 117.722 1.00 110.21 ? 94  VAL A O   1 
ATOM 163  C CB  . VAL A 1 94  ? 127.553 111.686 114.690 1.00 102.60 ? 94  VAL A CB  1 
ATOM 164  C CG1 . VAL A 1 94  ? 128.689 110.756 114.280 1.00 105.90 ? 94  VAL A CG1 1 
ATOM 165  C CG2 . VAL A 1 94  ? 126.216 110.966 114.608 1.00 94.88  ? 94  VAL A CG2 1 
ATOM 166  N N   . ALA A 1 95  ? 129.310 110.965 117.472 1.00 111.70 ? 95  ALA A N   1 
ATOM 167  C CA  . ALA A 1 95  ? 129.621 110.042 118.555 1.00 115.94 ? 95  ALA A CA  1 
ATOM 168  C C   . ALA A 1 95  ? 129.185 110.608 119.897 1.00 116.93 ? 95  ALA A C   1 
ATOM 169  O O   . ALA A 1 95  ? 128.623 109.885 120.728 1.00 120.39 ? 95  ALA A O   1 
ATOM 170  C CB  . ALA A 1 95  ? 131.116 109.724 118.563 1.00 115.61 ? 95  ALA A CB  1 
ATOM 171  N N   . LEU A 1 96  ? 129.415 111.904 120.116 1.00 115.98 ? 96  LEU A N   1 
ATOM 172  C CA  . LEU A 1 96  ? 128.960 112.534 121.349 1.00 117.38 ? 96  LEU A CA  1 
ATOM 173  C C   . LEU A 1 96  ? 127.439 112.598 121.424 1.00 118.31 ? 96  LEU A C   1 
ATOM 174  O O   . LEU A 1 96  ? 126.871 112.490 122.516 1.00 118.93 ? 96  LEU A O   1 
ATOM 175  C CB  . LEU A 1 96  ? 129.559 113.932 121.475 1.00 117.17 ? 96  LEU A CB  1 
ATOM 176  C CG  . LEU A 1 96  ? 131.051 113.992 121.801 1.00 119.03 ? 96  LEU A CG  1 
ATOM 177  C CD1 . LEU A 1 96  ? 131.559 115.424 121.731 1.00 119.02 ? 96  LEU A CD1 1 
ATOM 178  C CD2 . LEU A 1 96  ? 131.328 113.388 123.169 1.00 121.63 ? 96  LEU A CD2 1 
ATOM 179  N N   . ILE A 1 97  ? 126.767 112.784 120.284 1.00 119.21 ? 97  ILE A N   1 
ATOM 180  C CA  . ILE A 1 97  ? 125.306 112.854 120.284 1.00 116.15 ? 97  ILE A CA  1 
ATOM 181  C C   . ILE A 1 97  ? 124.700 111.481 120.566 1.00 116.64 ? 97  ILE A C   1 
ATOM 182  O O   . ILE A 1 97  ? 123.811 111.341 121.414 1.00 117.24 ? 97  ILE A O   1 
ATOM 183  C CB  . ILE A 1 97  ? 124.800 113.445 118.954 1.00 111.99 ? 97  ILE A CB  1 
ATOM 184  C CG1 . ILE A 1 97  ? 124.875 114.971 118.989 1.00 105.67 ? 97  ILE A CG1 1 
ATOM 185  C CG2 . ILE A 1 97  ? 123.370 113.003 118.650 1.00 103.69 ? 97  ILE A CG2 1 
ATOM 186  C CD1 . ILE A 1 97  ? 123.869 115.614 119.921 1.00 101.86 ? 97  ILE A CD1 1 
ATOM 187  N N   . ALA A 1 98  ? 125.187 110.444 119.879 1.00 118.88 ? 98  ALA A N   1 
ATOM 188  C CA  . ALA A 1 98  ? 124.593 109.118 120.009 1.00 119.70 ? 98  ALA A CA  1 
ATOM 189  C C   . ALA A 1 98  ? 125.011 108.407 121.288 1.00 119.56 ? 98  ALA A C   1 
ATOM 190  O O   . ALA A 1 98  ? 124.251 107.581 121.804 1.00 116.11 ? 98  ALA A O   1 
ATOM 191  C CB  . ALA A 1 98  ? 124.956 108.261 118.796 1.00 117.09 ? 98  ALA A CB  1 
ATOM 192  N N   . SER A 1 99  ? 126.207 108.694 121.806 1.00 122.38 ? 99  SER A N   1 
ATOM 193  C CA  . SER A 1 99  ? 126.703 107.970 122.972 1.00 123.46 ? 99  SER A CA  1 
ATOM 194  C C   . SER A 1 99  ? 125.973 108.391 124.240 1.00 122.20 ? 99  SER A C   1 
ATOM 195  O O   . SER A 1 99  ? 125.576 107.545 125.049 1.00 122.24 ? 99  SER A O   1 
ATOM 196  C CB  . SER A 1 99  ? 128.209 108.188 123.119 1.00 124.51 ? 99  SER A CB  1 
ATOM 197  O OG  . SER A 1 99  ? 128.500 109.545 123.406 1.00 123.40 ? 99  SER A OG  1 
ATOM 198  N N   . THR A 1 100 ? 125.787 109.689 124.432 1.00 123.42 ? 100 THR A N   1 
ATOM 199  C CA  . THR A 1 100 ? 125.150 110.183 125.645 1.00 125.33 ? 100 THR A CA  1 
ATOM 200  C C   . THR A 1 100 ? 123.645 109.965 125.564 1.00 124.92 ? 100 THR A C   1 
ATOM 201  O O   . THR A 1 100 ? 123.010 110.448 124.620 1.00 124.03 ? 100 THR A O   1 
ATOM 202  C CB  . THR A 1 100 ? 125.454 111.660 125.848 1.00 124.75 ? 100 THR A CB  1 
ATOM 203  O OG1 . THR A 1 100 ? 126.848 111.898 125.617 1.00 127.67 ? 100 THR A OG1 1 
ATOM 204  C CG2 . THR A 1 100 ? 125.102 112.083 127.266 1.00 119.48 ? 100 THR A CG2 1 
ATOM 205  N N   . PRO A 1 101 ? 123.039 109.249 126.516 1.00 125.29 ? 101 PRO A N   1 
ATOM 206  C CA  . PRO A 1 101 ? 121.584 109.031 126.464 1.00 123.58 ? 101 PRO A CA  1 
ATOM 207  C C   . PRO A 1 101 ? 120.764 110.258 126.822 1.00 123.27 ? 101 PRO A C   1 
ATOM 208  O O   . PRO A 1 101 ? 119.554 110.262 126.566 1.00 122.22 ? 101 PRO A O   1 
ATOM 209  C CB  . PRO A 1 101 ? 121.357 107.902 127.482 1.00 122.14 ? 101 PRO A CB  1 
ATOM 210  C CG  . PRO A 1 101 ? 122.730 107.392 127.849 1.00 125.80 ? 101 PRO A CG  1 
ATOM 211  C CD  . PRO A 1 101 ? 123.663 108.534 127.638 1.00 125.73 ? 101 PRO A CD  1 
ATOM 212  N N   . ALA A 1 102 ? 121.375 111.292 127.400 1.00 123.92 ? 102 ALA A N   1 
ATOM 213  C CA  . ALA A 1 102 ? 120.636 112.463 127.852 1.00 122.44 ? 102 ALA A CA  1 
ATOM 214  C C   . ALA A 1 102 ? 120.315 113.444 126.734 1.00 118.73 ? 102 ALA A C   1 
ATOM 215  O O   . ALA A 1 102 ? 119.509 114.354 126.950 1.00 118.33 ? 102 ALA A O   1 
ATOM 216  C CB  . ALA A 1 102 ? 121.422 113.189 128.947 1.00 122.26 ? 102 ALA A CB  1 
ATOM 217  N N   . LEU A 1 103 ? 120.917 113.290 125.557 1.00 115.99 ? 103 LEU A N   1 
ATOM 218  C CA  . LEU A 1 103 ? 120.753 114.252 124.469 1.00 111.21 ? 103 LEU A CA  1 
ATOM 219  C C   . LEU A 1 103 ? 119.782 113.676 123.442 1.00 107.76 ? 103 LEU A C   1 
ATOM 220  O O   . LEU A 1 103 ? 120.171 113.080 122.439 1.00 108.43 ? 103 LEU A O   1 
ATOM 221  C CB  . LEU A 1 103 ? 122.104 114.583 123.845 1.00 113.39 ? 103 LEU A CB  1 
ATOM 222  C CG  . LEU A 1 103 ? 123.296 114.680 124.796 1.00 116.50 ? 103 LEU A CG  1 
ATOM 223  C CD1 . LEU A 1 103 ? 124.582 114.809 124.003 1.00 116.27 ? 103 LEU A CD1 1 
ATOM 224  C CD2 . LEU A 1 103 ? 123.140 115.853 125.750 1.00 115.37 ? 103 LEU A CD2 1 
ATOM 225  N N   . ARG A 1 104 ? 118.486 113.858 123.708 1.00 102.03 ? 104 ARG A N   1 
ATOM 226  C CA  . ARG A 1 104 ? 117.443 113.386 122.805 1.00 99.36  ? 104 ARG A CA  1 
ATOM 227  C C   . ARG A 1 104 ? 116.389 114.447 122.508 1.00 91.41  ? 104 ARG A C   1 
ATOM 228  O O   . ARG A 1 104 ? 115.330 114.112 121.965 1.00 88.54  ? 104 ARG A O   1 
ATOM 229  C CB  . ARG A 1 104 ? 116.759 112.131 123.365 1.00 106.16 ? 104 ARG A CB  1 
ATOM 230  C CG  . ARG A 1 104 ? 117.686 110.954 123.626 1.00 109.54 ? 104 ARG A CG  1 
ATOM 231  C CD  . ARG A 1 104 ? 118.216 110.372 122.325 1.00 106.88 ? 104 ARG A CD  1 
ATOM 232  N NE  . ARG A 1 104 ? 119.183 109.304 122.553 1.00 108.11 ? 104 ARG A NE  1 
ATOM 233  C CZ  . ARG A 1 104 ? 120.463 109.496 122.843 1.00 112.54 ? 104 ARG A CZ  1 
ATOM 234  N NH1 . ARG A 1 104 ? 120.975 110.711 122.947 1.00 114.78 ? 104 ARG A NH1 1 
ATOM 235  N NH2 . ARG A 1 104 ? 121.249 108.441 123.032 1.00 113.65 ? 104 ARG A NH2 1 
ATOM 236  N N   . THR A 1 105 ? 116.646 115.708 122.843 1.00 91.56  ? 105 THR A N   1 
ATOM 237  C CA  . THR A 1 105 ? 115.695 116.776 122.590 1.00 91.76  ? 105 THR A CA  1 
ATOM 238  C C   . THR A 1 105 ? 115.605 117.039 121.085 1.00 90.76  ? 105 THR A C   1 
ATOM 239  O O   . THR A 1 105 ? 116.494 116.643 120.327 1.00 90.94  ? 105 THR A O   1 
ATOM 240  C CB  . THR A 1 105 ? 116.116 118.036 123.357 1.00 96.10  ? 105 THR A CB  1 
ATOM 241  O OG1 . THR A 1 105 ? 115.065 119.009 123.343 1.00 102.12 ? 105 THR A OG1 1 
ATOM 242  C CG2 . THR A 1 105 ? 117.353 118.657 122.744 1.00 96.62  ? 105 THR A CG2 1 
ATOM 243  N N   . PRO A 1 106 ? 114.505 117.645 120.620 1.00 92.64  ? 106 PRO A N   1 
ATOM 244  C CA  . PRO A 1 106 ? 114.402 117.986 119.188 1.00 94.04  ? 106 PRO A CA  1 
ATOM 245  C C   . PRO A 1 106 ? 115.499 118.904 118.664 1.00 92.87  ? 106 PRO A C   1 
ATOM 246  O O   . PRO A 1 106 ? 115.761 118.889 117.454 1.00 90.97  ? 106 PRO A O   1 
ATOM 247  C CB  . PRO A 1 106 ? 113.024 118.659 119.079 1.00 96.07  ? 106 PRO A CB  1 
ATOM 248  C CG  . PRO A 1 106 ? 112.360 118.505 120.425 1.00 94.64  ? 106 PRO A CG  1 
ATOM 249  C CD  . PRO A 1 106 ? 113.176 117.570 121.247 1.00 94.27  ? 106 PRO A CD  1 
ATOM 250  N N   . MET A 1 107 ? 116.133 119.713 119.513 1.00 93.44  ? 107 MET A N   1 
ATOM 251  C CA  . MET A 1 107 ? 117.273 120.501 119.054 1.00 93.97  ? 107 MET A CA  1 
ATOM 252  C C   . MET A 1 107 ? 118.476 119.611 118.767 1.00 90.38  ? 107 MET A C   1 
ATOM 253  O O   . MET A 1 107 ? 119.159 119.780 117.746 1.00 93.21  ? 107 MET A O   1 
ATOM 254  C CB  . MET A 1 107 ? 117.626 121.563 120.094 1.00 97.59  ? 107 MET A CB  1 
ATOM 255  C CG  . MET A 1 107 ? 118.899 122.332 119.796 1.00 104.34 ? 107 MET A CG  1 
ATOM 256  S SD  . MET A 1 107 ? 118.678 123.524 118.462 1.00 113.60 ? 107 MET A SD  1 
ATOM 257  C CE  . MET A 1 107 ? 120.370 124.041 118.187 1.00 97.03  ? 107 MET A CE  1 
ATOM 258  N N   . PHE A 1 108 ? 118.737 118.643 119.646 1.00 85.09  ? 108 PHE A N   1 
ATOM 259  C CA  . PHE A 1 108 ? 119.925 117.818 119.490 1.00 85.68  ? 108 PHE A CA  1 
ATOM 260  C C   . PHE A 1 108 ? 119.779 116.820 118.352 1.00 82.64  ? 108 PHE A C   1 
ATOM 261  O O   . PHE A 1 108 ? 120.779 116.465 117.724 1.00 86.72  ? 108 PHE A O   1 
ATOM 262  C CB  . PHE A 1 108 ? 120.256 117.103 120.797 1.00 92.91  ? 108 PHE A CB  1 
ATOM 263  C CG  . PHE A 1 108 ? 121.033 117.950 121.765 1.00 97.45  ? 108 PHE A CG  1 
ATOM 264  C CD1 . PHE A 1 108 ? 122.036 118.791 121.312 1.00 97.60  ? 108 PHE A CD1 1 
ATOM 265  C CD2 . PHE A 1 108 ? 120.782 117.885 123.125 1.00 103.03 ? 108 PHE A CD2 1 
ATOM 266  C CE1 . PHE A 1 108 ? 122.756 119.570 122.195 1.00 103.06 ? 108 PHE A CE1 1 
ATOM 267  C CE2 . PHE A 1 108 ? 121.500 118.662 124.015 1.00 107.39 ? 108 PHE A CE2 1 
ATOM 268  C CZ  . PHE A 1 108 ? 122.490 119.504 123.549 1.00 108.80 ? 108 PHE A CZ  1 
ATOM 269  N N   . VAL A 1 109 ? 118.557 116.376 118.047 1.00 78.23  ? 109 VAL A N   1 
ATOM 270  C CA  . VAL A 1 109 ? 118.396 115.479 116.906 1.00 77.66  ? 109 VAL A CA  1 
ATOM 271  C C   . VAL A 1 109 ? 118.609 116.231 115.594 1.00 79.75  ? 109 VAL A C   1 
ATOM 272  O O   . VAL A 1 109 ? 119.118 115.661 114.625 1.00 82.09  ? 109 VAL A O   1 
ATOM 273  C CB  . VAL A 1 109 ? 117.036 114.748 116.958 1.00 78.71  ? 109 VAL A CB  1 
ATOM 274  C CG1 . VAL A 1 109 ? 115.868 115.678 116.680 1.00 82.76  ? 109 VAL A CG1 1 
ATOM 275  C CG2 . VAL A 1 109 ? 117.024 113.564 115.998 1.00 73.87  ? 109 VAL A CG2 1 
ATOM 276  N N   . LEU A 1 110 ? 118.294 117.528 115.548 1.00 79.77  ? 110 LEU A N   1 
ATOM 277  C CA  . LEU A 1 110 ? 118.560 118.307 114.344 1.00 76.77  ? 110 LEU A CA  1 
ATOM 278  C C   . LEU A 1 110 ? 120.035 118.658 114.215 1.00 78.13  ? 110 LEU A C   1 
ATOM 279  O O   . LEU A 1 110 ? 120.577 118.681 113.100 1.00 79.57  ? 110 LEU A O   1 
ATOM 280  C CB  . LEU A 1 110 ? 117.705 119.569 114.341 1.00 76.59  ? 110 LEU A CB  1 
ATOM 281  C CG  . LEU A 1 110 ? 116.312 119.337 113.773 1.00 76.64  ? 110 LEU A CG  1 
ATOM 282  C CD1 . LEU A 1 110 ? 115.557 120.622 113.678 1.00 71.97  ? 110 LEU A CD1 1 
ATOM 283  C CD2 . LEU A 1 110 ? 116.446 118.746 112.405 1.00 72.85  ? 110 LEU A CD2 1 
ATOM 284  N N   . VAL A 1 111 ? 120.693 118.926 115.345 1.00 79.47  ? 111 VAL A N   1 
ATOM 285  C CA  . VAL A 1 111 ? 122.143 119.089 115.346 1.00 78.36  ? 111 VAL A CA  1 
ATOM 286  C C   . VAL A 1 111 ? 122.813 117.811 114.859 1.00 75.88  ? 111 VAL A C   1 
ATOM 287  O O   . VAL A 1 111 ? 123.735 117.846 114.034 1.00 76.84  ? 111 VAL A O   1 
ATOM 288  C CB  . VAL A 1 111 ? 122.626 119.497 116.751 1.00 81.96  ? 111 VAL A CB  1 
ATOM 289  C CG1 . VAL A 1 111 ? 124.113 119.241 116.920 1.00 83.07  ? 111 VAL A CG1 1 
ATOM 290  C CG2 . VAL A 1 111 ? 122.299 120.958 117.017 1.00 83.34  ? 111 VAL A CG2 1 
ATOM 291  N N   . GLY A 1 112 ? 122.322 116.660 115.320 1.00 78.70  ? 112 GLY A N   1 
ATOM 292  C CA  . GLY A 1 112 ? 122.840 115.392 114.842 1.00 81.52  ? 112 GLY A CA  1 
ATOM 293  C C   . GLY A 1 112 ? 122.542 115.137 113.377 1.00 78.74  ? 112 GLY A C   1 
ATOM 294  O O   . GLY A 1 112 ? 123.339 114.512 112.682 1.00 82.03  ? 112 GLY A O   1 
ATOM 295  N N   . SER A 1 113 ? 121.383 115.592 112.896 1.00 76.19  ? 113 SER A N   1 
ATOM 296  C CA  . SER A 1 113 ? 121.057 115.435 111.481 1.00 75.26  ? 113 SER A CA  1 
ATOM 297  C C   . SER A 1 113 ? 122.012 116.234 110.608 1.00 76.92  ? 113 SER A C   1 
ATOM 298  O O   . SER A 1 113 ? 122.493 115.735 109.583 1.00 79.32  ? 113 SER A O   1 
ATOM 299  C CB  . SER A 1 113 ? 119.613 115.863 111.224 1.00 78.12  ? 113 SER A CB  1 
ATOM 300  O OG  . SER A 1 113 ? 119.534 117.257 110.989 1.00 79.99  ? 113 SER A OG  1 
ATOM 301  N N   . LEU A 1 114 ? 122.317 117.467 111.020 1.00 76.52  ? 114 LEU A N   1 
ATOM 302  C CA  . LEU A 1 114 ? 123.342 118.251 110.337 1.00 73.10  ? 114 LEU A CA  1 
ATOM 303  C C   . LEU A 1 114 ? 124.703 117.572 110.430 1.00 75.58  ? 114 LEU A C   1 
ATOM 304  O O   . LEU A 1 114 ? 125.475 117.575 109.462 1.00 80.52  ? 114 LEU A O   1 
ATOM 305  C CB  . LEU A 1 114 ? 123.400 119.660 110.925 1.00 72.21  ? 114 LEU A CB  1 
ATOM 306  C CG  . LEU A 1 114 ? 124.574 120.553 110.530 1.00 71.79  ? 114 LEU A CG  1 
ATOM 307  C CD1 . LEU A 1 114 ? 124.450 120.978 109.081 1.00 67.31  ? 114 LEU A CD1 1 
ATOM 308  C CD2 . LEU A 1 114 ? 124.659 121.765 111.441 1.00 74.69  ? 114 LEU A CD2 1 
ATOM 309  N N   . ALA A 1 115 ? 124.991 116.948 111.575 1.00 73.56  ? 115 ALA A N   1 
ATOM 310  C CA  . ALA A 1 115 ? 126.269 116.272 111.770 1.00 78.61  ? 115 ALA A CA  1 
ATOM 311  C C   . ALA A 1 115 ? 126.434 115.087 110.823 1.00 82.66  ? 115 ALA A C   1 
ATOM 312  O O   . ALA A 1 115 ? 127.472 114.947 110.170 1.00 87.14  ? 115 ALA A O   1 
ATOM 313  C CB  . ALA A 1 115 ? 126.401 115.819 113.223 1.00 83.20  ? 115 ALA A CB  1 
ATOM 314  N N   . THR A 1 116 ? 125.420 114.220 110.733 1.00 78.87  ? 116 THR A N   1 
ATOM 315  C CA  . THR A 1 116 ? 125.515 113.080 109.822 1.00 79.34  ? 116 THR A CA  1 
ATOM 316  C C   . THR A 1 116 ? 125.465 113.504 108.365 1.00 81.27  ? 116 THR A C   1 
ATOM 317  O O   . THR A 1 116 ? 126.128 112.877 107.529 1.00 87.06  ? 116 THR A O   1 
ATOM 318  C CB  . THR A 1 116 ? 124.425 112.034 110.081 1.00 81.78  ? 116 THR A CB  1 
ATOM 319  O OG1 . THR A 1 116 ? 123.188 112.448 109.483 1.00 87.40  ? 116 THR A OG1 1 
ATOM 320  C CG2 . THR A 1 116 ? 124.260 111.712 111.554 1.00 84.60  ? 116 THR A CG2 1 
ATOM 321  N N   . ALA A 1 117 ? 124.700 114.550 108.034 1.00 77.10  ? 117 ALA A N   1 
ATOM 322  C CA  . ALA A 1 117 ? 124.695 115.045 106.662 1.00 78.19  ? 117 ALA A CA  1 
ATOM 323  C C   . ALA A 1 117 ? 126.070 115.557 106.259 1.00 81.09  ? 117 ALA A C   1 
ATOM 324  O O   . ALA A 1 117 ? 126.566 115.257 105.165 1.00 87.47  ? 117 ALA A O   1 
ATOM 325  C CB  . ALA A 1 117 ? 123.646 116.144 106.509 1.00 73.89  ? 117 ALA A CB  1 
ATOM 326  N N   . ASP A 1 118 ? 126.731 116.278 107.154 1.00 79.60  ? 118 ASP A N   1 
ATOM 327  C CA  . ASP A 1 118 ? 128.038 116.814 106.824 1.00 86.78  ? 118 ASP A CA  1 
ATOM 328  C C   . ASP A 1 118 ? 129.123 115.745 106.883 1.00 91.30  ? 118 ASP A C   1 
ATOM 329  O O   . ASP A 1 118 ? 130.120 115.835 106.155 1.00 96.69  ? 118 ASP A O   1 
ATOM 330  C CB  . ASP A 1 118 ? 128.340 117.971 107.763 1.00 91.86  ? 118 ASP A CB  1 
ATOM 331  C CG  . ASP A 1 118 ? 129.076 119.085 107.085 1.00 97.09  ? 118 ASP A CG  1 
ATOM 332  O OD1 . ASP A 1 118 ? 129.127 119.107 105.837 1.00 95.21  ? 118 ASP A OD1 1 
ATOM 333  O OD2 . ASP A 1 118 ? 129.569 119.965 107.806 1.00 97.80  ? 118 ASP A OD2 1 
ATOM 334  N N   . LEU A 1 119 ? 128.941 114.723 107.725 1.00 89.53  ? 119 LEU A N   1 
ATOM 335  C CA  . LEU A 1 119 ? 129.836 113.571 107.709 1.00 91.48  ? 119 LEU A CA  1 
ATOM 336  C C   . LEU A 1 119 ? 129.729 112.819 106.392 1.00 89.98  ? 119 LEU A C   1 
ATOM 337  O O   . LEU A 1 119 ? 130.743 112.384 105.829 1.00 93.96  ? 119 LEU A O   1 
ATOM 338  C CB  . LEU A 1 119 ? 129.516 112.649 108.885 1.00 94.79  ? 119 LEU A CB  1 
ATOM 339  C CG  . LEU A 1 119 ? 130.138 111.252 108.887 1.00 98.98  ? 119 LEU A CG  1 
ATOM 340  C CD1 . LEU A 1 119 ? 131.474 111.257 109.604 1.00 101.95 ? 119 LEU A CD1 1 
ATOM 341  C CD2 . LEU A 1 119 ? 129.188 110.247 109.521 1.00 97.76  ? 119 LEU A CD2 1 
ATOM 342  N N   . LEU A 1 120 ? 128.506 112.663 105.884 1.00 87.22  ? 120 LEU A N   1 
ATOM 343  C CA  . LEU A 1 120 ? 128.319 112.076 104.565 1.00 89.00  ? 120 LEU A CA  1 
ATOM 344  C C   . LEU A 1 120 ? 128.933 112.948 103.483 1.00 90.20  ? 120 LEU A C   1 
ATOM 345  O O   . LEU A 1 120 ? 129.445 112.427 102.490 1.00 94.67  ? 120 LEU A O   1 
ATOM 346  C CB  . LEU A 1 120 ? 126.831 111.857 104.292 1.00 87.05  ? 120 LEU A CB  1 
ATOM 347  C CG  . LEU A 1 120 ? 126.159 110.606 104.868 1.00 92.47  ? 120 LEU A CG  1 
ATOM 348  C CD1 . LEU A 1 120 ? 124.958 110.212 104.021 1.00 95.32  ? 120 LEU A CD1 1 
ATOM 349  C CD2 . LEU A 1 120 ? 127.130 109.437 104.991 1.00 93.99  ? 120 LEU A CD2 1 
ATOM 350  N N   . ALA A 1 121 ? 128.905 114.271 103.667 1.00 87.97  ? 121 ALA A N   1 
ATOM 351  C CA  . ALA A 1 121 ? 129.557 115.166 102.714 1.00 86.16  ? 121 ALA A CA  1 
ATOM 352  C C   . ALA A 1 121 ? 131.064 114.962 102.700 1.00 89.35  ? 121 ALA A C   1 
ATOM 353  O O   . ALA A 1 121 ? 131.684 114.899 101.632 1.00 92.15  ? 121 ALA A O   1 
ATOM 354  C CB  . ALA A 1 121 ? 129.211 116.619 103.038 1.00 84.45  ? 121 ALA A CB  1 
ATOM 355  N N   . GLY A 1 122 ? 131.669 114.853 103.883 1.00 92.57  ? 122 GLY A N   1 
ATOM 356  C CA  . GLY A 1 122 ? 133.102 114.610 103.950 1.00 98.62  ? 122 GLY A CA  1 
ATOM 357  C C   . GLY A 1 122 ? 133.491 113.269 103.357 1.00 98.16  ? 122 GLY A C   1 
ATOM 358  O O   . GLY A 1 122 ? 134.476 113.167 102.616 1.00 99.08  ? 122 GLY A O   1 
ATOM 359  N N   . CYS A 1 123 ? 132.703 112.230 103.651 1.00 98.03  ? 123 CYS A N   1 
ATOM 360  C CA  . CYS A 1 123 ? 132.938 110.919 103.058 1.00 101.90 ? 123 CYS A CA  1 
ATOM 361  C C   . CYS A 1 123 ? 132.761 110.951 101.547 1.00 101.43 ? 123 CYS A C   1 
ATOM 362  O O   . CYS A 1 123 ? 133.479 110.252 100.826 1.00 103.85 ? 123 CYS A O   1 
ATOM 363  C CB  . CYS A 1 123 ? 132.001 109.884 103.679 1.00 101.54 ? 123 CYS A CB  1 
ATOM 364  S SG  . CYS A 1 123 ? 132.320 108.185 103.155 1.00 114.76 ? 123 CYS A SG  1 
ATOM 365  N N   . GLY A 1 124 ? 131.823 111.761 101.054 1.00 96.16  ? 124 GLY A N   1 
ATOM 366  C CA  . GLY A 1 124 ? 131.660 111.907 99.620  1.00 96.20  ? 124 GLY A CA  1 
ATOM 367  C C   . GLY A 1 124 ? 132.844 112.582 98.959  1.00 98.83  ? 124 GLY A C   1 
ATOM 368  O O   . GLY A 1 124 ? 133.276 112.165 97.881  1.00 104.69 ? 124 GLY A O   1 
ATOM 369  N N   . LEU A 1 125 ? 133.379 113.639 99.590  1.00 92.67  ? 125 LEU A N   1 
ATOM 370  C CA  . LEU A 1 125 ? 134.603 114.264 99.088  1.00 92.80  ? 125 LEU A CA  1 
ATOM 371  C C   . LEU A 1 125 ? 135.754 113.268 99.036  1.00 98.52  ? 125 LEU A C   1 
ATOM 372  O O   . LEU A 1 125 ? 136.446 113.165 98.010  1.00 100.72 ? 125 LEU A O   1 
ATOM 373  C CB  . LEU A 1 125 ? 135.003 115.466 99.948  1.00 94.56  ? 125 LEU A CB  1 
ATOM 374  C CG  . LEU A 1 125 ? 134.538 116.916 99.728  1.00 97.62  ? 125 LEU A CG  1 
ATOM 375  C CD1 . LEU A 1 125 ? 135.108 117.464 98.429  1.00 98.55  ? 125 LEU A CD1 1 
ATOM 376  C CD2 . LEU A 1 125 ? 133.043 117.127 99.781  1.00 93.72  ? 125 LEU A CD2 1 
ATOM 377  N N   . ILE A 1 126 ? 135.944 112.504 100.119 1.00 100.31 ? 126 ILE A N   1 
ATOM 378  C CA  . ILE A 1 126 ? 137.040 111.538 100.180 1.00 102.20 ? 126 ILE A CA  1 
ATOM 379  C C   . ILE A 1 126 ? 136.874 110.465 99.109  1.00 101.15 ? 126 ILE A C   1 
ATOM 380  O O   . ILE A 1 126 ? 137.808 110.176 98.352  1.00 101.96 ? 126 ILE A O   1 
ATOM 381  C CB  . ILE A 1 126 ? 137.136 110.912 101.583 1.00 106.82 ? 126 ILE A CB  1 
ATOM 382  C CG1 . ILE A 1 126 ? 137.493 111.963 102.633 1.00 110.54 ? 126 ILE A CG1 1 
ATOM 383  C CG2 . ILE A 1 126 ? 138.149 109.775 101.601 1.00 104.74 ? 126 ILE A CG2 1 
ATOM 384  C CD1 . ILE A 1 126 ? 137.011 111.599 104.020 1.00 107.22 ? 126 ILE A CD1 1 
ATOM 385  N N   . LEU A 1 127 ? 135.674 109.887 99.008  1.00 100.89 ? 127 LEU A N   1 
ATOM 386  C CA  . LEU A 1 127 ? 135.448 108.794 98.070  1.00 102.62 ? 127 LEU A CA  1 
ATOM 387  C C   . LEU A 1 127 ? 135.544 109.263 96.625  1.00 103.32 ? 127 LEU A C   1 
ATOM 388  O O   . LEU A 1 127 ? 136.126 108.565 95.785  1.00 108.49 ? 127 LEU A O   1 
ATOM 389  C CB  . LEU A 1 127 ? 134.090 108.148 98.336  1.00 103.01 ? 127 LEU A CB  1 
ATOM 390  C CG  . LEU A 1 127 ? 134.105 106.806 99.073  1.00 106.57 ? 127 LEU A CG  1 
ATOM 391  C CD1 . LEU A 1 127 ? 134.870 105.764 98.272  1.00 108.57 ? 127 LEU A CD1 1 
ATOM 392  C CD2 . LEU A 1 127 ? 134.695 106.954 100.467 1.00 107.57 ? 127 LEU A CD2 1 
ATOM 393  N N   . HIS A 1 128 ? 135.008 110.451 96.321  1.00 98.37  ? 128 HIS A N   1 
ATOM 394  C CA  . HIS A 1 128 ? 135.070 110.974 94.962  1.00 97.08  ? 128 HIS A CA  1 
ATOM 395  C C   . HIS A 1 128 ? 136.506 111.255 94.546  1.00 102.24 ? 128 HIS A C   1 
ATOM 396  O O   . HIS A 1 128 ? 136.945 110.837 93.466  1.00 105.91 ? 128 HIS A O   1 
ATOM 397  C CB  . HIS A 1 128 ? 134.234 112.248 94.850  1.00 91.33  ? 128 HIS A CB  1 
ATOM 398  C CG  . HIS A 1 128 ? 134.627 113.120 93.701  1.00 92.77  ? 128 HIS A CG  1 
ATOM 399  N ND1 . HIS A 1 128 ? 134.453 112.742 92.389  1.00 90.92  ? 128 HIS A ND1 1 
ATOM 400  C CD2 . HIS A 1 128 ? 135.198 114.346 93.667  1.00 94.38  ? 128 HIS A CD2 1 
ATOM 401  C CE1 . HIS A 1 128 ? 134.891 113.702 91.595  1.00 90.85  ? 128 HIS A CE1 1 
ATOM 402  N NE2 . HIS A 1 128 ? 135.350 114.685 92.346  1.00 91.29  ? 128 HIS A NE2 1 
ATOM 403  N N   . PHE A 1 129 ? 137.261 111.954 95.396  1.00 100.85 ? 129 PHE A N   1 
ATOM 404  C CA  . PHE A 1 129 ? 138.608 112.321 94.996  1.00 101.98 ? 129 PHE A CA  1 
ATOM 405  C C   . PHE A 1 129 ? 139.589 111.166 95.121  1.00 105.00 ? 129 PHE A C   1 
ATOM 406  O O   . PHE A 1 129 ? 140.690 111.245 94.568  1.00 107.40 ? 129 PHE A O   1 
ATOM 407  C CB  . PHE A 1 129 ? 139.075 113.528 95.803  1.00 102.10 ? 129 PHE A CB  1 
ATOM 408  C CG  . PHE A 1 129 ? 138.508 114.823 95.305  1.00 104.35 ? 129 PHE A CG  1 
ATOM 409  C CD1 . PHE A 1 129 ? 138.568 115.140 93.958  1.00 106.03 ? 129 PHE A CD1 1 
ATOM 410  C CD2 . PHE A 1 129 ? 137.904 115.715 96.173  1.00 105.07 ? 129 PHE A CD2 1 
ATOM 411  C CE1 . PHE A 1 129 ? 138.047 116.323 93.485  1.00 106.80 ? 129 PHE A CE1 1 
ATOM 412  C CE2 . PHE A 1 129 ? 137.377 116.905 95.704  1.00 107.32 ? 129 PHE A CE2 1 
ATOM 413  C CZ  . PHE A 1 129 ? 137.450 117.209 94.359  1.00 108.94 ? 129 PHE A CZ  1 
ATOM 414  N N   . VAL A 1 130 ? 139.214 110.093 95.818  1.00 106.19 ? 130 VAL A N   1 
ATOM 415  C CA  . VAL A 1 130 ? 140.033 108.889 95.793  1.00 109.03 ? 130 VAL A CA  1 
ATOM 416  C C   . VAL A 1 130 ? 139.749 108.088 94.530  1.00 107.79 ? 130 VAL A C   1 
ATOM 417  O O   . VAL A 1 130 ? 140.676 107.636 93.847  1.00 110.57 ? 130 VAL A O   1 
ATOM 418  C CB  . VAL A 1 130 ? 139.807 108.065 97.077  1.00 111.12 ? 130 VAL A CB  1 
ATOM 419  C CG1 . VAL A 1 130 ? 140.056 106.575 96.845  1.00 109.22 ? 130 VAL A CG1 1 
ATOM 420  C CG2 . VAL A 1 130 ? 140.704 108.580 98.195  1.00 108.91 ? 130 VAL A CG2 1 
ATOM 421  N N   . PHE A 1 131 ? 138.472 107.934 94.169  1.00 107.29 ? 131 PHE A N   1 
ATOM 422  C CA  . PHE A 1 131 ? 138.130 107.080 93.039  1.00 108.30 ? 131 PHE A CA  1 
ATOM 423  C C   . PHE A 1 131 ? 138.472 107.716 91.699  1.00 108.91 ? 131 PHE A C   1 
ATOM 424  O O   . PHE A 1 131 ? 138.954 107.022 90.797  1.00 112.74 ? 131 PHE A O   1 
ATOM 425  C CB  . PHE A 1 131 ? 136.649 106.714 93.083  1.00 108.94 ? 131 PHE A CB  1 
ATOM 426  C CG  . PHE A 1 131 ? 136.351 105.499 93.909  1.00 116.51 ? 131 PHE A CG  1 
ATOM 427  C CD1 . PHE A 1 131 ? 137.380 104.742 94.451  1.00 118.70 ? 131 PHE A CD1 1 
ATOM 428  C CD2 . PHE A 1 131 ? 135.043 105.108 94.141  1.00 119.35 ? 131 PHE A CD2 1 
ATOM 429  C CE1 . PHE A 1 131 ? 137.109 103.620 95.211  1.00 122.49 ? 131 PHE A CE1 1 
ATOM 430  C CE2 . PHE A 1 131 ? 134.764 103.988 94.900  1.00 123.01 ? 131 PHE A CE2 1 
ATOM 431  C CZ  . PHE A 1 131 ? 135.799 103.243 95.436  1.00 125.17 ? 131 PHE A CZ  1 
ATOM 432  N N   . GLN A 1 132 ? 138.234 109.019 91.530  1.00 105.20 ? 132 GLN A N   1 
ATOM 433  C CA  . GLN A 1 132 ? 138.426 109.596 90.206  1.00 104.47 ? 132 GLN A CA  1 
ATOM 434  C C   . GLN A 1 132 ? 139.904 109.850 89.904  1.00 108.33 ? 132 GLN A C   1 
ATOM 435  O O   . GLN A 1 132 ? 140.283 109.902 88.729  1.00 104.50 ? 132 GLN A O   1 
ATOM 436  C CB  . GLN A 1 132 ? 137.527 110.839 90.072  1.00 104.76 ? 132 GLN A CB  1 
ATOM 437  C CG  . GLN A 1 132 ? 138.002 112.072 89.308  1.00 109.61 ? 132 GLN A CG  1 
ATOM 438  C CD  . GLN A 1 132 ? 138.884 112.995 90.106  1.00 112.93 ? 132 GLN A CD  1 
ATOM 439  O OE1 . GLN A 1 132 ? 138.546 113.388 91.222  1.00 113.38 ? 132 GLN A OE1 1 
ATOM 440  N NE2 . GLN A 1 132 ? 139.979 113.419 89.500  1.00 114.12 ? 132 GLN A NE2 1 
ATOM 441  N N   . TYR A 1 133 ? 140.754 109.944 90.933  1.00 113.64 ? 133 TYR A N   1 
ATOM 442  C CA  . TYR A 1 133 ? 142.197 109.757 90.780  1.00 117.71 ? 133 TYR A CA  1 
ATOM 443  C C   . TYR A 1 133 ? 142.629 108.296 90.775  1.00 116.76 ? 133 TYR A C   1 
ATOM 444  O O   . TYR A 1 133 ? 143.763 108.007 90.381  1.00 114.61 ? 133 TYR A O   1 
ATOM 445  C CB  . TYR A 1 133 ? 142.975 110.474 91.891  1.00 118.88 ? 133 TYR A CB  1 
ATOM 446  C CG  . TYR A 1 133 ? 143.512 111.834 91.514  1.00 124.49 ? 133 TYR A CG  1 
ATOM 447  C CD1 . TYR A 1 133 ? 142.699 112.789 90.936  1.00 124.68 ? 133 TYR A CD1 1 
ATOM 448  C CD2 . TYR A 1 133 ? 144.849 112.153 91.729  1.00 127.26 ? 133 TYR A CD2 1 
ATOM 449  C CE1 . TYR A 1 133 ? 143.192 114.029 90.579  1.00 127.60 ? 133 TYR A CE1 1 
ATOM 450  C CE2 . TYR A 1 133 ? 145.352 113.392 91.381  1.00 125.93 ? 133 TYR A CE2 1 
ATOM 451  C CZ  . TYR A 1 133 ? 144.519 114.327 90.806  1.00 126.68 ? 133 TYR A CZ  1 
ATOM 452  O OH  . TYR A 1 133 ? 145.013 115.563 90.457  1.00 123.77 ? 133 TYR A OH  1 
ATOM 453  N N   . LEU A 1 134 ? 141.768 107.374 91.200  1.00 116.12 ? 134 LEU A N   1 
ATOM 454  C CA  . LEU A 1 134 ? 142.115 105.959 91.254  1.00 113.04 ? 134 LEU A CA  1 
ATOM 455  C C   . LEU A 1 134 ? 141.638 105.221 90.010  1.00 113.43 ? 134 LEU A C   1 
ATOM 456  O O   . LEU A 1 134 ? 142.432 104.564 89.329  1.00 118.19 ? 134 LEU A O   1 
ATOM 457  C CB  . LEU A 1 134 ? 141.522 105.320 92.514  1.00 114.43 ? 134 LEU A CB  1 
ATOM 458  C CG  . LEU A 1 134 ? 141.759 103.818 92.674  1.00 113.03 ? 134 LEU A CG  1 
ATOM 459  C CD1 . LEU A 1 134 ? 143.244 103.526 92.819  1.00 109.84 ? 134 LEU A CD1 1 
ATOM 460  C CD2 . LEU A 1 134 ? 140.984 103.278 93.865  1.00 113.78 ? 134 LEU A CD2 1 
ATOM 461  N N   . VAL A 1 135 ? 140.351 105.316 89.699  1.00 111.02 ? 135 VAL A N   1 
ATOM 462  C CA  . VAL A 1 135 ? 139.820 104.689 88.495  1.00 109.50 ? 135 VAL A CA  1 
ATOM 463  C C   . VAL A 1 135 ? 139.110 105.728 87.631  1.00 109.41 ? 135 VAL A C   1 
ATOM 464  O O   . VAL A 1 135 ? 138.093 106.310 88.037  1.00 106.95 ? 135 VAL A O   1 
ATOM 465  C CB  . VAL A 1 135 ? 138.939 103.473 88.846  1.00 108.16 ? 135 VAL A CB  1 
ATOM 466  C CG1 . VAL A 1 135 ? 137.859 103.801 89.887  1.00 108.91 ? 135 VAL A CG1 1 
ATOM 467  C CG2 . VAL A 1 135 ? 138.318 102.894 87.586  1.00 107.33 ? 135 VAL A CG2 1 
ATOM 468  N N   . PRO A 1 136 ? 139.647 106.043 86.455  1.00 112.98 ? 136 PRO A N   1 
ATOM 469  C CA  . PRO A 1 136 ? 138.946 106.937 85.525  1.00 112.25 ? 136 PRO A CA  1 
ATOM 470  C C   . PRO A 1 136 ? 137.802 106.207 84.830  1.00 105.49 ? 136 PRO A C   1 
ATOM 471  O O   . PRO A 1 136 ? 138.017 105.394 83.931  1.00 105.52 ? 136 PRO A O   1 
ATOM 472  C CB  . PRO A 1 136 ? 140.048 107.350 84.539  1.00 113.57 ? 136 PRO A CB  1 
ATOM 473  C CG  . PRO A 1 136 ? 141.073 106.276 84.623  1.00 114.38 ? 136 PRO A CG  1 
ATOM 474  C CD  . PRO A 1 136 ? 141.018 105.730 86.014  1.00 113.09 ? 136 PRO A CD  1 
ATOM 475  N N   . SER A 1 137 ? 136.579 106.515 85.250  1.00 99.96  ? 137 SER A N   1 
ATOM 476  C CA  . SER A 1 137 ? 135.392 105.880 84.699  1.00 97.09  ? 137 SER A CA  1 
ATOM 477  C C   . SER A 1 137 ? 134.192 106.765 84.994  1.00 96.00  ? 137 SER A C   1 
ATOM 478  O O   . SER A 1 137 ? 134.047 107.266 86.112  1.00 96.68  ? 137 SER A O   1 
ATOM 479  C CB  . SER A 1 137 ? 135.192 104.480 85.284  1.00 96.57  ? 137 SER A CB  1 
ATOM 480  O OG  . SER A 1 137 ? 135.551 104.461 86.651  1.00 94.73  ? 137 SER A OG  1 
ATOM 481  N N   . GLU A 1 138 ? 133.336 106.945 83.988  1.00 90.16  ? 138 GLU A N   1 
ATOM 482  C CA  . GLU A 1 138 ? 132.246 107.907 84.099  1.00 83.71  ? 138 GLU A CA  1 
ATOM 483  C C   . GLU A 1 138 ? 131.088 107.433 84.972  1.00 82.13  ? 138 GLU A C   1 
ATOM 484  O O   . GLU A 1 138 ? 130.404 108.276 85.562  1.00 86.50  ? 138 GLU A O   1 
ATOM 485  C CB  . GLU A 1 138 ? 131.748 108.304 82.701  1.00 83.37  ? 138 GLU A CB  1 
ATOM 486  C CG  . GLU A 1 138 ? 130.691 107.425 81.971  1.00 83.67  ? 138 GLU A CG  1 
ATOM 487  C CD  . GLU A 1 138 ? 131.020 105.926 81.781  1.00 90.16  ? 138 GLU A CD  1 
ATOM 488  O OE1 . GLU A 1 138 ? 131.818 105.303 82.512  1.00 90.04  ? 138 GLU A OE1 1 
ATOM 489  O OE2 . GLU A 1 138 ? 130.438 105.348 80.840  1.00 94.28  ? 138 GLU A OE2 1 
ATOM 490  N N   . THR A 1 139 ? 130.846 106.121 85.085  1.00 80.22  ? 139 THR A N   1 
ATOM 491  C CA  . THR A 1 139 ? 129.737 105.658 85.921  1.00 82.83  ? 139 THR A CA  1 
ATOM 492  C C   . THR A 1 139 ? 129.980 105.963 87.394  1.00 82.09  ? 139 THR A C   1 
ATOM 493  O O   . THR A 1 139 ? 129.130 106.568 88.059  1.00 79.79  ? 139 THR A O   1 
ATOM 494  C CB  . THR A 1 139 ? 129.487 104.157 85.743  1.00 86.94  ? 139 THR A CB  1 
ATOM 495  O OG1 . THR A 1 139 ? 130.300 103.417 86.664  1.00 89.49  ? 139 THR A OG1 1 
ATOM 496  C CG2 . THR A 1 139 ? 129.754 103.695 84.326  1.00 84.63  ? 139 THR A CG2 1 
ATOM 497  N N   . VAL A 1 140 ? 131.142 105.571 87.920  1.00 86.96  ? 140 VAL A N   1 
ATOM 498  C CA  . VAL A 1 140 ? 131.386 105.772 89.344  1.00 90.93  ? 140 VAL A CA  1 
ATOM 499  C C   . VAL A 1 140 ? 131.629 107.248 89.643  1.00 91.92  ? 140 VAL A C   1 
ATOM 500  O O   . VAL A 1 140 ? 131.280 107.728 90.728  1.00 93.97  ? 140 VAL A O   1 
ATOM 501  C CB  . VAL A 1 140 ? 132.536 104.864 89.838  1.00 96.09  ? 140 VAL A CB  1 
ATOM 502  C CG1 . VAL A 1 140 ? 133.896 105.326 89.331  1.00 94.63  ? 140 VAL A CG1 1 
ATOM 503  C CG2 . VAL A 1 140 ? 132.531 104.762 91.359  1.00 98.64  ? 140 VAL A CG2 1 
ATOM 504  N N   . SER A 1 141 ? 132.167 108.001 88.678  1.00 92.07  ? 141 SER A N   1 
ATOM 505  C CA  . SER A 1 141 ? 132.348 109.437 88.871  1.00 96.87  ? 141 SER A CA  1 
ATOM 506  C C   . SER A 1 141 ? 131.007 110.157 88.915  1.00 90.32  ? 141 SER A C   1 
ATOM 507  O O   . SER A 1 141 ? 130.796 111.031 89.765  1.00 89.65  ? 141 SER A O   1 
ATOM 508  C CB  . SER A 1 141 ? 133.232 110.012 87.765  1.00 97.28  ? 141 SER A CB  1 
ATOM 509  O OG  . SER A 1 141 ? 134.440 109.282 87.647  1.00 98.43  ? 141 SER A OG  1 
ATOM 510  N N   . LEU A 1 142 ? 130.084 109.788 88.021  1.00 82.21  ? 142 LEU A N   1 
ATOM 511  C CA  . LEU A 1 142 ? 128.743 110.356 88.055  1.00 78.46  ? 142 LEU A CA  1 
ATOM 512  C C   . LEU A 1 142 ? 128.029 109.973 89.344  1.00 81.54  ? 142 LEU A C   1 
ATOM 513  O O   . LEU A 1 142 ? 127.328 110.799 89.941  1.00 82.69  ? 142 LEU A O   1 
ATOM 514  C CB  . LEU A 1 142 ? 127.957 109.886 86.829  1.00 82.12  ? 142 LEU A CB  1 
ATOM 515  C CG  . LEU A 1 142 ? 126.843 110.726 86.187  1.00 89.91  ? 142 LEU A CG  1 
ATOM 516  C CD1 . LEU A 1 142 ? 126.457 110.113 84.851  1.00 91.60  ? 142 LEU A CD1 1 
ATOM 517  C CD2 . LEU A 1 142 ? 125.602 110.865 87.062  1.00 91.44  ? 142 LEU A CD2 1 
ATOM 518  N N   . LEU A 1 143 ? 128.215 108.729 89.796  1.00 83.60  ? 143 LEU A N   1 
ATOM 519  C CA  . LEU A 1 143 ? 127.563 108.271 91.018  1.00 85.49  ? 143 LEU A CA  1 
ATOM 520  C C   . LEU A 1 143 ? 128.065 109.032 92.238  1.00 83.62  ? 143 LEU A C   1 
ATOM 521  O O   . LEU A 1 143 ? 127.269 109.468 93.080  1.00 87.38  ? 143 LEU A O   1 
ATOM 522  C CB  . LEU A 1 143 ? 127.783 106.769 91.197  1.00 88.24  ? 143 LEU A CB  1 
ATOM 523  C CG  . LEU A 1 143 ? 127.224 106.142 92.475  1.00 90.20  ? 143 LEU A CG  1 
ATOM 524  C CD1 . LEU A 1 143 ? 125.705 106.215 92.491  1.00 88.01  ? 143 LEU A CD1 1 
ATOM 525  C CD2 . LEU A 1 143 ? 127.699 104.704 92.620  1.00 91.18  ? 143 LEU A CD2 1 
ATOM 526  N N   . THR A 1 144 ? 129.378 109.230 92.341  1.00 80.85  ? 144 THR A N   1 
ATOM 527  C CA  . THR A 1 144 ? 129.892 109.940 93.502  1.00 86.15  ? 144 THR A CA  1 
ATOM 528  C C   . THR A 1 144 ? 129.646 111.445 93.412  1.00 85.80  ? 144 THR A C   1 
ATOM 529  O O   . THR A 1 144 ? 129.525 112.106 94.451  1.00 86.82  ? 144 THR A O   1 
ATOM 530  C CB  . THR A 1 144 ? 131.376 109.618 93.705  1.00 94.39  ? 144 THR A CB  1 
ATOM 531  O OG1 . THR A 1 144 ? 131.802 110.112 94.981  1.00 97.09  ? 144 THR A OG1 1 
ATOM 532  C CG2 . THR A 1 144 ? 132.238 110.208 92.602  1.00 95.45  ? 144 THR A CG2 1 
ATOM 533  N N   . VAL A 1 145 ? 129.506 111.998 92.201  1.00 83.42  ? 145 VAL A N   1 
ATOM 534  C CA  . VAL A 1 145 ? 129.102 113.395 92.073  1.00 79.88  ? 145 VAL A CA  1 
ATOM 535  C C   . VAL A 1 145 ? 127.660 113.570 92.528  1.00 71.96  ? 145 VAL A C   1 
ATOM 536  O O   . VAL A 1 145 ? 127.326 114.535 93.230  1.00 71.82  ? 145 VAL A O   1 
ATOM 537  C CB  . VAL A 1 145 ? 129.327 113.878 90.626  1.00 80.82  ? 145 VAL A CB  1 
ATOM 538  C CG1 . VAL A 1 145 ? 128.427 115.050 90.276  1.00 75.42  ? 145 VAL A CG1 1 
ATOM 539  C CG2 . VAL A 1 145 ? 130.784 114.267 90.425  1.00 85.00  ? 145 VAL A CG2 1 
ATOM 540  N N   . GLY A 1 146 ? 126.789 112.626 92.167  1.00 74.92  ? 146 GLY A N   1 
ATOM 541  C CA  . GLY A 1 146 ? 125.425 112.657 92.670  1.00 77.87  ? 146 GLY A CA  1 
ATOM 542  C C   . GLY A 1 146 ? 125.355 112.485 94.175  1.00 74.38  ? 146 GLY A C   1 
ATOM 543  O O   . GLY A 1 146 ? 124.512 113.094 94.842  1.00 75.20  ? 146 GLY A O   1 
ATOM 544  N N   . PHE A 1 147 ? 126.247 111.661 94.729  1.00 70.63  ? 147 PHE A N   1 
ATOM 545  C CA  . PHE A 1 147 ? 126.330 111.530 96.180  1.00 72.44  ? 147 PHE A CA  1 
ATOM 546  C C   . PHE A 1 147 ? 126.753 112.841 96.829  1.00 79.90  ? 147 PHE A C   1 
ATOM 547  O O   . PHE A 1 147 ? 126.228 113.216 97.885  1.00 84.11  ? 147 PHE A O   1 
ATOM 548  C CB  . PHE A 1 147 ? 127.299 110.412 96.553  1.00 77.27  ? 147 PHE A CB  1 
ATOM 549  C CG  . PHE A 1 147 ? 127.324 110.102 98.016  1.00 81.51  ? 147 PHE A CG  1 
ATOM 550  C CD1 . PHE A 1 147 ? 126.268 109.435 98.613  1.00 87.56  ? 147 PHE A CD1 1 
ATOM 551  C CD2 . PHE A 1 147 ? 128.401 110.480 98.798  1.00 81.19  ? 147 PHE A CD2 1 
ATOM 552  C CE1 . PHE A 1 147 ? 126.285 109.148 99.965  1.00 88.50  ? 147 PHE A CE1 1 
ATOM 553  C CE2 . PHE A 1 147 ? 128.426 110.196 100.150 1.00 87.59  ? 147 PHE A CE2 1 
ATOM 554  C CZ  . PHE A 1 147 ? 127.367 109.530 100.734 1.00 87.81  ? 147 PHE A CZ  1 
ATOM 555  N N   . LEU A 1 148 ? 127.694 113.557 96.203  1.00 78.71  ? 148 LEU A N   1 
ATOM 556  C CA  . LEU A 1 148 ? 128.099 114.869 96.705  1.00 78.40  ? 148 LEU A CA  1 
ATOM 557  C C   . LEU A 1 148 ? 126.951 115.865 96.660  1.00 74.59  ? 148 LEU A C   1 
ATOM 558  O O   . LEU A 1 148 ? 126.780 116.669 97.586  1.00 72.73  ? 148 LEU A O   1 
ATOM 559  C CB  . LEU A 1 148 ? 129.280 115.401 95.896  1.00 80.19  ? 148 LEU A CB  1 
ATOM 560  C CG  . LEU A 1 148 ? 130.676 115.086 96.428  1.00 88.82  ? 148 LEU A CG  1 
ATOM 561  C CD1 . LEU A 1 148 ? 131.686 116.087 95.898  1.00 91.74  ? 148 LEU A CD1 1 
ATOM 562  C CD2 . LEU A 1 148 ? 130.664 115.089 97.941  1.00 89.76  ? 148 LEU A CD2 1 
ATOM 563  N N   . VAL A 1 149 ? 126.172 115.838 95.578  1.00 72.38  ? 149 VAL A N   1 
ATOM 564  C CA  . VAL A 1 149 ? 125.037 116.747 95.432  1.00 66.23  ? 149 VAL A CA  1 
ATOM 565  C C   . VAL A 1 149 ? 123.999 116.475 96.514  1.00 66.69  ? 149 VAL A C   1 
ATOM 566  O O   . VAL A 1 149 ? 123.499 117.401 97.170  1.00 72.62  ? 149 VAL A O   1 
ATOM 567  C CB  . VAL A 1 149 ? 124.442 116.621 94.018  1.00 69.60  ? 149 VAL A CB  1 
ATOM 568  C CG1 . VAL A 1 149 ? 122.965 116.990 93.991  1.00 74.92  ? 149 VAL A CG1 1 
ATOM 569  C CG2 . VAL A 1 149 ? 125.220 117.489 93.056  1.00 69.39  ? 149 VAL A CG2 1 
ATOM 570  N N   . ALA A 1 150 ? 123.696 115.193 96.740  1.00 67.67  ? 150 ALA A N   1 
ATOM 571  C CA  . ALA A 1 150 ? 122.746 114.815 97.780  1.00 67.70  ? 150 ALA A CA  1 
ATOM 572  C C   . ALA A 1 150 ? 123.254 115.197 99.162  1.00 63.76  ? 150 ALA A C   1 
ATOM 573  O O   . ALA A 1 150 ? 122.480 115.647 100.013 1.00 69.15  ? 150 ALA A O   1 
ATOM 574  C CB  . ALA A 1 150 ? 122.463 113.315 97.710  1.00 73.12  ? 150 ALA A CB  1 
ATOM 575  N N   . SER A 1 151 ? 124.560 115.066 99.389  1.00 59.78  ? 151 SER A N   1 
ATOM 576  C CA  . SER A 1 151 ? 125.123 115.396 100.692 1.00 66.41  ? 151 SER A CA  1 
ATOM 577  C C   . SER A 1 151 ? 125.090 116.895 100.966 1.00 69.06  ? 151 SER A C   1 
ATOM 578  O O   . SER A 1 151 ? 124.756 117.320 102.080 1.00 65.59  ? 151 SER A O   1 
ATOM 579  C CB  . SER A 1 151 ? 126.549 114.876 100.770 1.00 72.32  ? 151 SER A CB  1 
ATOM 580  O OG  . SER A 1 151 ? 127.452 115.812 100.209 1.00 76.90  ? 151 SER A OG  1 
ATOM 581  N N   . PHE A 1 152 ? 125.451 117.712 99.971  1.00 73.33  ? 152 PHE A N   1 
ATOM 582  C CA  . PHE A 1 152 ? 125.409 119.162 100.149 1.00 69.61  ? 152 PHE A CA  1 
ATOM 583  C C   . PHE A 1 152 ? 123.980 119.654 100.332 1.00 62.59  ? 152 PHE A C   1 
ATOM 584  O O   . PHE A 1 152 ? 123.723 120.548 101.154 1.00 63.66  ? 152 PHE A O   1 
ATOM 585  C CB  . PHE A 1 152 ? 126.063 119.856 98.959  1.00 72.52  ? 152 PHE A CB  1 
ATOM 586  C CG  . PHE A 1 152 ? 127.559 119.839 98.997  1.00 75.29  ? 152 PHE A CG  1 
ATOM 587  C CD1 . PHE A 1 152 ? 128.234 119.808 100.202 1.00 76.07  ? 152 PHE A CD1 1 
ATOM 588  C CD2 . PHE A 1 152 ? 128.290 119.854 97.824  1.00 79.80  ? 152 PHE A CD2 1 
ATOM 589  C CE1 . PHE A 1 152 ? 129.614 119.793 100.239 1.00 82.67  ? 152 PHE A CE1 1 
ATOM 590  C CE2 . PHE A 1 152 ? 129.669 119.839 97.851  1.00 84.88  ? 152 PHE A CE2 1 
ATOM 591  C CZ  . PHE A 1 152 ? 130.332 119.809 99.063  1.00 87.88  ? 152 PHE A CZ  1 
ATOM 592  N N   . ALA A 1 153 ? 123.039 119.077 99.576  1.00 59.81  ? 153 ALA A N   1 
ATOM 593  C CA  . ALA A 1 153 ? 121.634 119.408 99.765  1.00 57.13  ? 153 ALA A CA  1 
ATOM 594  C C   . ALA A 1 153 ? 121.162 119.006 101.153 1.00 61.31  ? 153 ALA A C   1 
ATOM 595  O O   . ALA A 1 153 ? 120.380 119.728 101.780 1.00 68.50  ? 153 ALA A O   1 
ATOM 596  C CB  . ALA A 1 153 ? 120.785 118.733 98.690  1.00 63.16  ? 153 ALA A CB  1 
ATOM 597  N N   . ALA A 1 154 ? 121.653 117.871 101.659 1.00 60.95  ? 154 ALA A N   1 
ATOM 598  C CA  . ALA A 1 154 ? 121.310 117.438 103.008 1.00 60.09  ? 154 ALA A CA  1 
ATOM 599  C C   . ALA A 1 154 ? 121.841 118.406 104.056 1.00 60.18  ? 154 ALA A C   1 
ATOM 600  O O   . ALA A 1 154 ? 121.145 118.713 105.030 1.00 64.18  ? 154 ALA A O   1 
ATOM 601  C CB  . ALA A 1 154 ? 121.849 116.031 103.256 1.00 61.68  ? 154 ALA A CB  1 
ATOM 602  N N   . SER A 1 155 ? 123.063 118.908 103.865 1.00 58.05  ? 155 SER A N   1 
ATOM 603  C CA  . SER A 1 155 ? 123.641 119.852 104.820 1.00 57.27  ? 155 SER A CA  1 
ATOM 604  C C   . SER A 1 155 ? 122.867 121.168 104.849 1.00 59.43  ? 155 SER A C   1 
ATOM 605  O O   . SER A 1 155 ? 122.507 121.670 105.927 1.00 63.50  ? 155 SER A O   1 
ATOM 606  C CB  . SER A 1 155 ? 125.109 120.104 104.482 1.00 61.81  ? 155 SER A CB  1 
ATOM 607  O OG  . SER A 1 155 ? 125.259 121.305 103.747 1.00 65.11  ? 155 SER A OG  1 
ATOM 608  N N   . VAL A 1 156 ? 122.583 121.728 103.670 1.00 57.39  ? 156 VAL A N   1 
ATOM 609  C CA  . VAL A 1 156 ? 121.855 122.995 103.591 1.00 53.65  ? 156 VAL A CA  1 
ATOM 610  C C   . VAL A 1 156 ? 120.433 122.835 104.125 1.00 53.20  ? 156 VAL A C   1 
ATOM 611  O O   . VAL A 1 156 ? 119.925 123.687 104.874 1.00 58.93  ? 156 VAL A O   1 
ATOM 612  C CB  . VAL A 1 156 ? 121.881 123.517 102.141 1.00 55.37  ? 156 VAL A CB  1 
ATOM 613  C CG1 . VAL A 1 156 ? 120.787 124.529 101.891 1.00 56.06  ? 156 VAL A CG1 1 
ATOM 614  C CG2 . VAL A 1 156 ? 123.239 124.119 101.828 1.00 61.21  ? 156 VAL A CG2 1 
ATOM 615  N N   . SER A 1 157 ? 119.788 121.719 103.794 1.00 51.66  ? 157 SER A N   1 
ATOM 616  C CA  . SER A 1 157 ? 118.440 121.455 104.270 1.00 52.42  ? 157 SER A CA  1 
ATOM 617  C C   . SER A 1 157 ? 118.393 121.227 105.774 1.00 53.82  ? 157 SER A C   1 
ATOM 618  O O   . SER A 1 157 ? 117.421 121.623 106.426 1.00 57.59  ? 157 SER A O   1 
ATOM 619  C CB  . SER A 1 157 ? 117.883 120.247 103.532 1.00 60.89  ? 157 SER A CB  1 
ATOM 620  O OG  . SER A 1 157 ? 117.981 119.081 104.331 1.00 68.37  ? 157 SER A OG  1 
ATOM 621  N N   . SER A 1 158 ? 119.419 120.596 106.346 1.00 54.01  ? 158 SER A N   1 
ATOM 622  C CA  . SER A 1 158 ? 119.453 120.430 107.792 1.00 53.42  ? 158 SER A CA  1 
ATOM 623  C C   . SER A 1 158 ? 119.673 121.759 108.493 1.00 55.30  ? 158 SER A C   1 
ATOM 624  O O   . SER A 1 158 ? 119.140 121.978 109.590 1.00 62.54  ? 158 SER A O   1 
ATOM 625  C CB  . SER A 1 158 ? 120.535 119.429 108.178 1.00 60.13  ? 158 SER A CB  1 
ATOM 626  O OG  . SER A 1 158 ? 121.763 119.748 107.554 1.00 62.68  ? 158 SER A OG  1 
ATOM 627  N N   . LEU A 1 159 ? 120.435 122.661 107.869 1.00 53.94  ? 159 LEU A N   1 
ATOM 628  C CA  . LEU A 1 159 ? 120.551 124.015 108.403 1.00 55.78  ? 159 LEU A CA  1 
ATOM 629  C C   . LEU A 1 159 ? 119.200 124.722 108.397 1.00 53.07  ? 159 LEU A C   1 
ATOM 630  O O   . LEU A 1 159 ? 118.840 125.410 109.364 1.00 54.65  ? 159 LEU A O   1 
ATOM 631  C CB  . LEU A 1 159 ? 121.575 124.806 107.595 1.00 61.02  ? 159 LEU A CB  1 
ATOM 632  C CG  . LEU A 1 159 ? 122.422 125.775 108.410 1.00 68.16  ? 159 LEU A CG  1 
ATOM 633  C CD1 . LEU A 1 159 ? 123.097 125.021 109.535 1.00 72.36  ? 159 LEU A CD1 1 
ATOM 634  C CD2 . LEU A 1 159 ? 123.453 126.453 107.539 1.00 72.85  ? 159 LEU A CD2 1 
ATOM 635  N N   . LEU A 1 160 ? 118.430 124.538 107.322 1.00 50.54  ? 160 LEU A N   1 
ATOM 636  C CA  . LEU A 1 160 ? 117.077 125.088 107.265 1.00 46.84  ? 160 LEU A CA  1 
ATOM 637  C C   . LEU A 1 160 ? 116.184 124.489 108.345 1.00 48.22  ? 160 LEU A C   1 
ATOM 638  O O   . LEU A 1 160 ? 115.359 125.193 108.941 1.00 55.15  ? 160 LEU A O   1 
ATOM 639  C CB  . LEU A 1 160 ? 116.471 124.848 105.884 1.00 46.90  ? 160 LEU A CB  1 
ATOM 640  C CG  . LEU A 1 160 ? 114.976 125.118 105.726 1.00 45.47  ? 160 LEU A CG  1 
ATOM 641  C CD1 . LEU A 1 160 ? 114.695 126.587 105.944 1.00 47.86  ? 160 LEU A CD1 1 
ATOM 642  C CD2 . LEU A 1 160 ? 114.488 124.674 104.361 1.00 47.19  ? 160 LEU A CD2 1 
ATOM 643  N N   . ALA A 1 161 ? 116.335 123.190 108.608 1.00 47.72  ? 161 ALA A N   1 
ATOM 644  C CA  . ALA A 1 161 ? 115.532 122.537 109.637 1.00 47.89  ? 161 ALA A CA  1 
ATOM 645  C C   . ALA A 1 161 ? 115.852 123.076 111.027 1.00 49.98  ? 161 ALA A C   1 
ATOM 646  O O   . ALA A 1 161 ? 114.946 123.271 111.850 1.00 54.26  ? 161 ALA A O   1 
ATOM 647  C CB  . ALA A 1 161 ? 115.745 121.027 109.582 1.00 51.23  ? 161 ALA A CB  1 
ATOM 648  N N   . ILE A 1 162 ? 117.133 123.325 111.308 1.00 47.54  ? 162 ILE A N   1 
ATOM 649  C CA  . ILE A 1 162 ? 117.502 123.920 112.593 1.00 47.45  ? 162 ILE A CA  1 
ATOM 650  C C   . ILE A 1 162 ? 116.947 125.338 112.705 1.00 48.78  ? 162 ILE A C   1 
ATOM 651  O O   . ILE A 1 162 ? 116.461 125.752 113.769 1.00 54.66  ? 162 ILE A O   1 
ATOM 652  C CB  . ILE A 1 162 ? 119.028 123.883 112.786 1.00 54.37  ? 162 ILE A CB  1 
ATOM 653  C CG1 . ILE A 1 162 ? 119.528 122.442 112.777 1.00 62.58  ? 162 ILE A CG1 1 
ATOM 654  C CG2 . ILE A 1 162 ? 119.418 124.513 114.104 1.00 60.11  ? 162 ILE A CG2 1 
ATOM 655  C CD1 . ILE A 1 162 ? 121.035 122.320 112.765 1.00 67.34  ? 162 ILE A CD1 1 
ATOM 656  N N   . THR A 1 163 ? 116.978 126.092 111.605 1.00 46.43  ? 163 THR A N   1 
ATOM 657  C CA  . THR A 1 163 ? 116.405 127.436 111.622 1.00 46.23  ? 163 THR A CA  1 
ATOM 658  C C   . THR A 1 163 ? 114.903 127.395 111.902 1.00 44.94  ? 163 THR A C   1 
ATOM 659  O O   . THR A 1 163 ? 114.388 128.166 112.730 1.00 51.00  ? 163 THR A O   1 
ATOM 660  C CB  . THR A 1 163 ? 116.707 128.130 110.293 1.00 51.62  ? 163 THR A CB  1 
ATOM 661  O OG1 . THR A 1 163 ? 118.042 128.647 110.325 1.00 54.97  ? 163 THR A OG1 1 
ATOM 662  C CG2 . THR A 1 163 ? 115.756 129.279 110.035 1.00 51.45  ? 163 THR A CG2 1 
ATOM 663  N N   . VAL A 1 164 ? 114.196 126.449 111.282 1.00 42.00  ? 164 VAL A N   1 
ATOM 664  C CA  . VAL A 1 164 ? 112.750 126.411 111.444 1.00 41.71  ? 164 VAL A CA  1 
ATOM 665  C C   . VAL A 1 164 ? 112.351 125.878 112.818 1.00 42.36  ? 164 VAL A C   1 
ATOM 666  O O   . VAL A 1 164 ? 111.321 126.296 113.361 1.00 44.48  ? 164 VAL A O   1 
ATOM 667  C CB  . VAL A 1 164 ? 112.087 125.632 110.290 1.00 41.77  ? 164 VAL A CB  1 
ATOM 668  C CG1 . VAL A 1 164 ? 112.127 124.140 110.506 1.00 46.80  ? 164 VAL A CG1 1 
ATOM 669  C CG2 . VAL A 1 164 ? 110.653 126.091 110.100 1.00 42.86  ? 164 VAL A CG2 1 
ATOM 670  N N   . ASP A 1 165 ? 113.151 125.003 113.446 1.00 45.88  ? 165 ASP A N   1 
ATOM 671  C CA  . ASP A 1 165 ? 112.715 124.613 114.782 1.00 47.65  ? 165 ASP A CA  1 
ATOM 672  C C   . ASP A 1 165 ? 113.098 125.653 115.821 1.00 46.79  ? 165 ASP A C   1 
ATOM 673  O O   . ASP A 1 165 ? 112.428 125.741 116.853 1.00 49.99  ? 165 ASP A O   1 
ATOM 674  C CB  . ASP A 1 165 ? 113.194 123.201 115.189 1.00 58.28  ? 165 ASP A CB  1 
ATOM 675  C CG  . ASP A 1 165 ? 114.601 123.142 115.806 1.00 65.56  ? 165 ASP A CG  1 
ATOM 676  O OD1 . ASP A 1 165 ? 115.476 123.998 115.597 1.00 62.98  ? 165 ASP A OD1 1 
ATOM 677  O OD2 . ASP A 1 165 ? 114.832 122.172 116.558 1.00 71.96  ? 165 ASP A OD2 1 
ATOM 678  N N   . ARG A 1 166 ? 114.131 126.459 115.554 1.00 44.68  ? 166 ARG A N   1 
ATOM 679  C CA  . ARG A 1 166 ? 114.367 127.643 116.374 1.00 42.61  ? 166 ARG A CA  1 
ATOM 680  C C   . ARG A 1 166 ? 113.175 128.592 116.310 1.00 44.31  ? 166 ARG A C   1 
ATOM 681  O O   . ARG A 1 166 ? 112.707 129.098 117.341 1.00 46.22  ? 166 ARG A O   1 
ATOM 682  C CB  . ARG A 1 166 ? 115.636 128.351 115.908 1.00 47.93  ? 166 ARG A CB  1 
ATOM 683  C CG  . ARG A 1 166 ? 116.901 127.868 116.570 1.00 54.98  ? 166 ARG A CG  1 
ATOM 684  C CD  . ARG A 1 166 ? 118.111 128.147 115.704 1.00 63.14  ? 166 ARG A CD  1 
ATOM 685  N NE  . ARG A 1 166 ? 119.343 128.127 116.480 1.00 68.58  ? 166 ARG A NE  1 
ATOM 686  C CZ  . ARG A 1 166 ? 120.319 129.013 116.351 1.00 72.14  ? 166 ARG A CZ  1 
ATOM 687  N NH1 . ARG A 1 166 ? 120.248 129.995 115.469 1.00 76.03  ? 166 ARG A NH1 1 
ATOM 688  N NH2 . ARG A 1 166 ? 121.396 128.908 117.123 1.00 74.50  ? 166 ARG A NH2 1 
ATOM 689  N N   . TYR A 1 167 ? 112.655 128.820 115.100 1.00 43.65  ? 167 TYR A N   1 
ATOM 690  C CA  . TYR A 1 167 ? 111.491 129.690 114.941 1.00 42.02  ? 167 TYR A CA  1 
ATOM 691  C C   . TYR A 1 167 ? 110.259 129.112 115.626 1.00 44.79  ? 167 TYR A C   1 
ATOM 692  O O   . TYR A 1 167 ? 109.482 129.850 116.245 1.00 50.18  ? 167 TYR A O   1 
ATOM 693  C CB  . TYR A 1 167 ? 111.209 129.926 113.462 1.00 40.57  ? 167 TYR A CB  1 
ATOM 694  C CG  . TYR A 1 167 ? 109.829 130.463 113.178 1.00 40.49  ? 167 TYR A CG  1 
ATOM 695  C CD1 . TYR A 1 167 ? 109.487 131.757 113.519 1.00 46.33  ? 167 TYR A CD1 1 
ATOM 696  C CD2 . TYR A 1 167 ? 108.873 129.677 112.557 1.00 43.00  ? 167 TYR A CD2 1 
ATOM 697  C CE1 . TYR A 1 167 ? 108.233 132.254 113.256 1.00 47.52  ? 167 TYR A CE1 1 
ATOM 698  C CE2 . TYR A 1 167 ? 107.614 130.166 112.291 1.00 46.34  ? 167 TYR A CE2 1 
ATOM 699  C CZ  . TYR A 1 167 ? 107.301 131.456 112.644 1.00 49.96  ? 167 TYR A CZ  1 
ATOM 700  O OH  . TYR A 1 167 ? 106.047 131.951 112.382 1.00 60.46  ? 167 TYR A OH  1 
ATOM 701  N N   . LEU A 1 168 ? 110.061 127.797 115.522 1.00 44.63  ? 168 LEU A N   1 
ATOM 702  C CA  . LEU A 1 168 ? 108.904 127.172 116.155 1.00 42.83  ? 168 LEU A CA  1 
ATOM 703  C C   . LEU A 1 168 ? 109.016 127.197 117.672 1.00 47.09  ? 168 LEU A C   1 
ATOM 704  O O   . LEU A 1 168 ? 108.011 127.367 118.370 1.00 52.19  ? 168 LEU A O   1 
ATOM 705  C CB  . LEU A 1 168 ? 108.740 125.741 115.654 1.00 44.79  ? 168 LEU A CB  1 
ATOM 706  C CG  . LEU A 1 168 ? 108.059 125.592 114.297 1.00 49.05  ? 168 LEU A CG  1 
ATOM 707  C CD1 . LEU A 1 168 ? 107.773 124.130 114.004 1.00 52.21  ? 168 LEU A CD1 1 
ATOM 708  C CD2 . LEU A 1 168 ? 106.783 126.411 114.242 1.00 49.14  ? 168 LEU A CD2 1 
ATOM 709  N N   . SER A 1 169 ? 110.226 127.029 118.203 1.00 47.01  ? 169 SER A N   1 
ATOM 710  C CA  . SER A 1 169 ? 110.415 127.099 119.643 1.00 47.47  ? 169 SER A CA  1 
ATOM 711  C C   . SER A 1 169 ? 110.310 128.519 120.169 1.00 46.39  ? 169 SER A C   1 
ATOM 712  O O   . SER A 1 169 ? 110.055 128.704 121.361 1.00 48.30  ? 169 SER A O   1 
ATOM 713  C CB  . SER A 1 169 ? 111.769 126.511 120.025 1.00 50.02  ? 169 SER A CB  1 
ATOM 714  O OG  . SER A 1 169 ? 112.780 127.500 119.963 1.00 52.82  ? 169 SER A OG  1 
ATOM 715  N N   . LEU A 1 170 ? 110.520 129.523 119.322 1.00 47.50  ? 170 LEU A N   1 
ATOM 716  C CA  . LEU A 1 170 ? 110.399 130.895 119.794 1.00 49.32  ? 170 LEU A CA  1 
ATOM 717  C C   . LEU A 1 170 ? 109.000 131.477 119.632 1.00 49.76  ? 170 LEU A C   1 
ATOM 718  O O   . LEU A 1 170 ? 108.585 132.290 120.464 1.00 50.73  ? 170 LEU A O   1 
ATOM 719  C CB  . LEU A 1 170 ? 111.401 131.792 119.069 1.00 50.84  ? 170 LEU A CB  1 
ATOM 720  C CG  . LEU A 1 170 ? 112.668 132.145 119.840 1.00 50.92  ? 170 LEU A CG  1 
ATOM 721  C CD1 . LEU A 1 170 ? 113.372 133.288 119.154 1.00 50.58  ? 170 LEU A CD1 1 
ATOM 722  C CD2 . LEU A 1 170 ? 112.355 132.500 121.280 1.00 46.03  ? 170 LEU A CD2 1 
ATOM 723  N N   . TYR A 1 171 ? 108.259 131.102 118.591 1.00 48.54  ? 171 TYR A N   1 
ATOM 724  C CA  . TYR A 1 171 ? 106.953 131.702 118.348 1.00 47.37  ? 171 TYR A CA  1 
ATOM 725  C C   . TYR A 1 171 ? 105.787 130.807 118.740 1.00 49.37  ? 171 TYR A C   1 
ATOM 726  O O   . TYR A 1 171 ? 104.651 131.286 118.795 1.00 55.18  ? 171 TYR A O   1 
ATOM 727  C CB  . TYR A 1 171 ? 106.805 132.095 116.877 1.00 49.05  ? 171 TYR A CB  1 
ATOM 728  C CG  . TYR A 1 171 ? 107.316 133.477 116.560 1.00 52.88  ? 171 TYR A CG  1 
ATOM 729  C CD1 . TYR A 1 171 ? 108.450 133.975 117.174 1.00 52.20  ? 171 TYR A CD1 1 
ATOM 730  C CD2 . TYR A 1 171 ? 106.648 134.290 115.660 1.00 58.81  ? 171 TYR A CD2 1 
ATOM 731  C CE1 . TYR A 1 171 ? 108.917 135.233 116.887 1.00 56.79  ? 171 TYR A CE1 1 
ATOM 732  C CE2 . TYR A 1 171 ? 107.105 135.554 115.371 1.00 61.37  ? 171 TYR A CE2 1 
ATOM 733  C CZ  . TYR A 1 171 ? 108.240 136.021 115.987 1.00 60.50  ? 171 TYR A CZ  1 
ATOM 734  O OH  . TYR A 1 171 ? 108.702 137.285 115.701 1.00 59.89  ? 171 TYR A OH  1 
ATOM 735  N N   . ASN A 1 172 ? 106.036 129.531 119.002 1.00 46.55  ? 172 ASN A N   1 
ATOM 736  C CA  . ASN A 1 172 ? 105.024 128.626 119.525 1.00 50.30  ? 172 ASN A CA  1 
ATOM 737  C C   . ASN A 1 172 ? 105.585 128.027 120.801 1.00 52.33  ? 172 ASN A C   1 
ATOM 738  O O   . ASN A 1 172 ? 105.585 126.805 120.979 1.00 58.58  ? 172 ASN A O   1 
ATOM 739  C CB  . ASN A 1 172 ? 104.674 127.541 118.509 1.00 58.29  ? 172 ASN A CB  1 
ATOM 740  C CG  . ASN A 1 172 ? 103.191 127.239 118.467 1.00 65.51  ? 172 ASN A CG  1 
ATOM 741  O OD1 . ASN A 1 172 ? 102.377 127.993 119.000 1.00 64.50  ? 172 ASN A OD1 1 
ATOM 742  N ND2 . ASN A 1 172 ? 102.830 126.131 117.832 1.00 66.87  ? 172 ASN A ND2 1 
ATOM 743  N N   . ALA A 1 173 ? 106.078 128.906 121.678 1.00 52.34  ? 173 ALA A N   1 
ATOM 744  C CA  . ALA A 1 173 ? 107.044 128.517 122.701 1.00 55.99  ? 173 ALA A CA  1 
ATOM 745  C C   . ALA A 1 173 ? 106.447 127.583 123.741 1.00 53.60  ? 173 ALA A C   1 
ATOM 746  O O   . ALA A 1 173 ? 107.065 126.576 124.101 1.00 56.36  ? 173 ALA A O   1 
ATOM 747  C CB  . ALA A 1 173 ? 107.611 129.765 123.373 1.00 54.70  ? 173 ALA A CB  1 
ATOM 748  N N   . LEU A 1 174 ? 105.257 127.890 124.236 1.00 47.41  ? 174 LEU A N   1 
ATOM 749  C CA  . LEU A 1 174 ? 104.724 127.130 125.353 1.00 51.61  ? 174 LEU A CA  1 
ATOM 750  C C   . LEU A 1 174 ? 103.873 125.942 124.924 1.00 59.61  ? 174 LEU A C   1 
ATOM 751  O O   . LEU A 1 174 ? 103.465 125.152 125.781 1.00 61.51  ? 174 LEU A O   1 
ATOM 752  C CB  . LEU A 1 174 ? 103.935 128.056 126.278 1.00 52.55  ? 174 LEU A CB  1 
ATOM 753  C CG  . LEU A 1 174 ? 102.448 128.295 126.075 1.00 57.87  ? 174 LEU A CG  1 
ATOM 754  C CD1 . LEU A 1 174 ? 101.926 128.902 127.352 1.00 54.59  ? 174 LEU A CD1 1 
ATOM 755  C CD2 . LEU A 1 174 ? 102.182 129.208 124.891 1.00 60.29  ? 174 LEU A CD2 1 
ATOM 756  N N   . THR A 1 175 ? 103.607 125.788 123.626 1.00 61.53  ? 175 THR A N   1 
ATOM 757  C CA  . THR A 1 175 ? 103.002 124.579 123.082 1.00 61.37  ? 175 THR A CA  1 
ATOM 758  C C   . THR A 1 175 ? 103.983 123.802 122.210 1.00 62.76  ? 175 THR A C   1 
ATOM 759  O O   . THR A 1 175 ? 103.564 122.993 121.378 1.00 65.90  ? 175 THR A O   1 
ATOM 760  C CB  . THR A 1 175 ? 101.745 124.915 122.277 1.00 61.38  ? 175 THR A CB  1 
ATOM 761  O OG1 . THR A 1 175 ? 102.103 125.176 120.916 1.00 65.05  ? 175 THR A OG1 1 
ATOM 762  C CG2 . THR A 1 175 ? 101.042 126.136 122.847 1.00 57.54  ? 175 THR A CG2 1 
ATOM 763  N N   . TYR A 1 176 ? 105.284 124.038 122.390 1.00 60.64  ? 176 TYR A N   1 
ATOM 764  C CA  . TYR A 1 176 ? 106.293 123.518 121.473 1.00 62.85  ? 176 TYR A CA  1 
ATOM 765  C C   . TYR A 1 176 ? 106.467 122.014 121.602 1.00 66.40  ? 176 TYR A C   1 
ATOM 766  O O   . TYR A 1 176 ? 106.747 121.337 120.606 1.00 71.83  ? 176 TYR A O   1 
ATOM 767  C CB  . TYR A 1 176 ? 107.619 124.233 121.726 1.00 61.54  ? 176 TYR A CB  1 
ATOM 768  C CG  . TYR A 1 176 ? 108.829 123.603 121.078 1.00 63.36  ? 176 TYR A CG  1 
ATOM 769  C CD1 . TYR A 1 176 ? 109.018 123.666 119.706 1.00 62.87  ? 176 TYR A CD1 1 
ATOM 770  C CD2 . TYR A 1 176 ? 109.796 122.969 121.844 1.00 65.78  ? 176 TYR A CD2 1 
ATOM 771  C CE1 . TYR A 1 176 ? 110.129 123.103 119.114 1.00 63.16  ? 176 TYR A CE1 1 
ATOM 772  C CE2 . TYR A 1 176 ? 110.909 122.403 121.261 1.00 65.24  ? 176 TYR A CE2 1 
ATOM 773  C CZ  . TYR A 1 176 ? 111.070 122.473 119.896 1.00 65.60  ? 176 TYR A CZ  1 
ATOM 774  O OH  . TYR A 1 176 ? 112.179 121.907 119.314 1.00 74.23  ? 176 TYR A OH  1 
ATOM 775  N N   . TYR A 1 177 ? 106.297 121.471 122.801 1.00 64.12  ? 177 TYR A N   1 
ATOM 776  C CA  . TYR A 1 177 ? 106.505 120.048 123.021 1.00 66.91  ? 177 TYR A CA  1 
ATOM 777  C C   . TYR A 1 177 ? 105.275 119.213 122.700 1.00 71.32  ? 177 TYR A C   1 
ATOM 778  O O   . TYR A 1 177 ? 105.307 117.995 122.901 1.00 76.21  ? 177 TYR A O   1 
ATOM 779  C CB  . TYR A 1 177 ? 106.935 119.800 124.464 1.00 70.50  ? 177 TYR A CB  1 
ATOM 780  C CG  . TYR A 1 177 ? 108.264 120.421 124.818 1.00 72.03  ? 177 TYR A CG  1 
ATOM 781  C CD1 . TYR A 1 177 ? 109.454 119.784 124.500 1.00 72.24  ? 177 TYR A CD1 1 
ATOM 782  C CD2 . TYR A 1 177 ? 108.329 121.640 125.476 1.00 74.04  ? 177 TYR A CD2 1 
ATOM 783  C CE1 . TYR A 1 177 ? 110.672 120.342 124.822 1.00 73.64  ? 177 TYR A CE1 1 
ATOM 784  C CE2 . TYR A 1 177 ? 109.542 122.210 125.804 1.00 76.33  ? 177 TYR A CE2 1 
ATOM 785  C CZ  . TYR A 1 177 ? 110.711 121.557 125.474 1.00 78.55  ? 177 TYR A CZ  1 
ATOM 786  O OH  . TYR A 1 177 ? 111.924 122.121 125.799 1.00 82.46  ? 177 TYR A OH  1 
ATOM 787  N N   . SER A 1 178 ? 104.202 119.830 122.213 1.00 68.16  ? 178 SER A N   1 
ATOM 788  C CA  . SER A 1 178 ? 103.001 119.098 121.854 1.00 74.49  ? 178 SER A CA  1 
ATOM 789  C C   . SER A 1 178 ? 103.234 118.266 120.592 1.00 81.41  ? 178 SER A C   1 
ATOM 790  O O   . SER A 1 178 ? 104.210 118.449 119.858 1.00 84.80  ? 178 SER A O   1 
ATOM 791  C CB  . SER A 1 178 ? 101.831 120.059 121.656 1.00 75.43  ? 178 SER A CB  1 
ATOM 792  O OG  . SER A 1 178 ? 100.743 119.418 121.014 1.00 84.48  ? 178 SER A OG  1 
ATOM 793  N N   . ARG A 1 179 ? 102.311 117.329 120.358 1.00 80.89  ? 179 ARG A N   1 
ATOM 794  C CA  . ARG A 1 179 ? 102.438 116.381 119.254 1.00 83.92  ? 179 ARG A CA  1 
ATOM 795  C C   . ARG A 1 179 ? 102.331 117.091 117.908 1.00 86.28  ? 179 ARG A C   1 
ATOM 796  O O   . ARG A 1 179 ? 103.098 116.803 116.981 1.00 86.78  ? 179 ARG A O   1 
ATOM 797  C CB  . ARG A 1 179 ? 101.346 115.310 119.385 1.00 87.66  ? 179 ARG A CB  1 
ATOM 798  C CG  . ARG A 1 179 ? 101.270 114.090 118.407 1.00 95.57  ? 179 ARG A CG  1 
ATOM 799  C CD  . ARG A 1 179 ? 102.490 113.665 117.554 1.00 97.19  ? 179 ARG A CD  1 
ATOM 800  N NE  . ARG A 1 179 ? 103.747 113.598 118.293 1.00 100.59 ? 179 ARG A NE  1 
ATOM 801  C CZ  . ARG A 1 179 ? 104.947 113.524 117.736 1.00 98.53  ? 179 ARG A CZ  1 
ATOM 802  N NH1 . ARG A 1 179 ? 105.096 113.441 116.426 1.00 95.39  ? 179 ARG A NH1 1 
ATOM 803  N NH2 . ARG A 1 179 ? 106.024 113.512 118.516 1.00 98.91  ? 179 ARG A NH2 1 
ATOM 804  N N   . ARG A 1 180 ? 101.386 118.031 117.791 1.00 84.12  ? 180 ARG A N   1 
ATOM 805  C CA  . ARG A 1 180 ? 101.123 118.712 116.527 1.00 82.84  ? 180 ARG A CA  1 
ATOM 806  C C   . ARG A 1 180 ? 102.263 119.625 116.101 1.00 86.61  ? 180 ARG A C   1 
ATOM 807  O O   . ARG A 1 180 ? 102.349 119.973 114.919 1.00 87.95  ? 180 ARG A O   1 
ATOM 808  C CB  . ARG A 1 180 ? 99.829  119.519 116.625 1.00 80.41  ? 180 ARG A CB  1 
ATOM 809  N N   . THR A 1 181 ? 103.127 120.027 117.028 1.00 87.68  ? 181 THR A N   1 
ATOM 810  C CA  . THR A 1 181 ? 104.333 120.768 116.686 1.00 85.65  ? 181 THR A CA  1 
ATOM 811  C C   . THR A 1 181 ? 105.549 119.868 116.549 1.00 81.54  ? 181 THR A C   1 
ATOM 812  O O   . THR A 1 181 ? 106.414 120.135 115.709 1.00 82.82  ? 181 THR A O   1 
ATOM 813  C CB  . THR A 1 181 ? 104.612 121.843 117.745 1.00 84.84  ? 181 THR A CB  1 
ATOM 814  O OG1 . THR A 1 181 ? 103.379 122.455 118.140 1.00 83.87  ? 181 THR A OG1 1 
ATOM 815  C CG2 . THR A 1 181 ? 105.540 122.922 117.195 1.00 78.77  ? 181 THR A CG2 1 
ATOM 816  N N   . LEU A 1 182 ? 105.623 118.795 117.336 1.00 81.18  ? 182 LEU A N   1 
ATOM 817  C CA  . LEU A 1 182 ? 106.771 117.902 117.279 1.00 83.56  ? 182 LEU A CA  1 
ATOM 818  C C   . LEU A 1 182 ? 106.759 117.013 116.043 1.00 85.74  ? 182 LEU A C   1 
ATOM 819  O O   . LEU A 1 182 ? 107.819 116.533 115.631 1.00 86.16  ? 182 LEU A O   1 
ATOM 820  C CB  . LEU A 1 182 ? 106.823 117.043 118.541 1.00 85.81  ? 182 LEU A CB  1 
ATOM 821  C CG  . LEU A 1 182 ? 108.173 116.465 118.977 1.00 85.81  ? 182 LEU A CG  1 
ATOM 822  C CD1 . LEU A 1 182 ? 109.334 117.359 118.562 1.00 83.94  ? 182 LEU A CD1 1 
ATOM 823  C CD2 . LEU A 1 182 ? 108.186 116.239 120.480 1.00 83.64  ? 182 LEU A CD2 1 
ATOM 824  N N   . LEU A 1 183 ? 105.588 116.773 115.447 1.00 87.16  ? 183 LEU A N   1 
ATOM 825  C CA  . LEU A 1 183 ? 105.541 115.978 114.225 1.00 87.27  ? 183 LEU A CA  1 
ATOM 826  C C   . LEU A 1 183 ? 106.075 116.754 113.033 1.00 85.16  ? 183 LEU A C   1 
ATOM 827  O O   . LEU A 1 183 ? 106.581 116.149 112.080 1.00 87.70  ? 183 LEU A O   1 
ATOM 828  C CB  . LEU A 1 183 ? 104.108 115.517 113.955 1.00 92.91  ? 183 LEU A CB  1 
ATOM 829  C CG  . LEU A 1 183 ? 103.908 114.356 112.977 1.00 94.17  ? 183 LEU A CG  1 
ATOM 830  C CD1 . LEU A 1 183 ? 102.926 113.344 113.538 1.00 95.86  ? 183 LEU A CD1 1 
ATOM 831  C CD2 . LEU A 1 183 ? 103.428 114.860 111.626 1.00 92.67  ? 183 LEU A CD2 1 
ATOM 832  N N   . GLY A 1 184 ? 105.964 118.084 113.073 1.00 83.46  ? 184 GLY A N   1 
ATOM 833  C CA  . GLY A 1 184 ? 106.364 118.894 111.936 1.00 84.45  ? 184 GLY A CA  1 
ATOM 834  C C   . GLY A 1 184 ? 107.855 118.848 111.674 1.00 84.42  ? 184 GLY A C   1 
ATOM 835  O O   . GLY A 1 184 ? 108.285 118.794 110.520 1.00 84.72  ? 184 GLY A O   1 
ATOM 836  N N   . VAL A 1 185 ? 108.658 118.841 112.738 1.00 82.21  ? 185 VAL A N   1 
ATOM 837  C CA  . VAL A 1 185 ? 110.110 118.796 112.590 1.00 81.31  ? 185 VAL A CA  1 
ATOM 838  C C   . VAL A 1 185 ? 110.551 117.469 111.982 1.00 80.25  ? 185 VAL A C   1 
ATOM 839  O O   . VAL A 1 185 ? 111.375 117.439 111.059 1.00 82.65  ? 185 VAL A O   1 
ATOM 840  C CB  . VAL A 1 185 ? 110.784 119.055 113.949 1.00 84.32  ? 185 VAL A CB  1 
ATOM 841  C CG1 . VAL A 1 185 ? 112.279 118.791 113.876 1.00 80.07  ? 185 VAL A CG1 1 
ATOM 842  C CG2 . VAL A 1 185 ? 110.512 120.480 114.410 1.00 82.27  ? 185 VAL A CG2 1 
ATOM 843  N N   . HIS A 1 186 ? 109.997 116.356 112.472 1.00 78.03  ? 186 HIS A N   1 
ATOM 844  C CA  . HIS A 1 186 ? 110.359 115.042 111.942 1.00 76.19  ? 186 HIS A CA  1 
ATOM 845  C C   . HIS A 1 186 ? 109.883 114.872 110.505 1.00 75.13  ? 186 HIS A C   1 
ATOM 846  O O   . HIS A 1 186 ? 110.613 114.330 109.662 1.00 75.88  ? 186 HIS A O   1 
ATOM 847  C CB  . HIS A 1 186 ? 109.801 113.911 112.817 1.00 79.52  ? 186 HIS A CB  1 
ATOM 848  C CG  . HIS A 1 186 ? 109.888 114.141 114.300 1.00 87.32  ? 186 HIS A CG  1 
ATOM 849  N ND1 . HIS A 1 186 ? 110.753 115.043 114.886 1.00 90.32  ? 186 HIS A ND1 1 
ATOM 850  C CD2 . HIS A 1 186 ? 109.200 113.573 115.319 1.00 91.88  ? 186 HIS A CD2 1 
ATOM 851  C CE1 . HIS A 1 186 ? 110.596 115.017 116.197 1.00 91.77  ? 186 HIS A CE1 1 
ATOM 852  N NE2 . HIS A 1 186 ? 109.658 114.134 116.486 1.00 92.36  ? 186 HIS A NE2 1 
ATOM 853  N N   . LEU A 1 187 ? 108.667 115.339 110.204 1.00 74.62  ? 187 LEU A N   1 
ATOM 854  C CA  . LEU A 1 187 ? 108.157 115.255 108.842 1.00 77.39  ? 187 LEU A CA  1 
ATOM 855  C C   . LEU A 1 187 ? 108.985 116.108 107.892 1.00 79.85  ? 187 LEU A C   1 
ATOM 856  O O   . LEU A 1 187 ? 109.250 115.704 106.753 1.00 81.64  ? 187 LEU A O   1 
ATOM 857  C CB  . LEU A 1 187 ? 106.690 115.679 108.807 1.00 83.00  ? 187 LEU A CB  1 
ATOM 858  C CG  . LEU A 1 187 ? 105.988 115.598 107.451 1.00 89.79  ? 187 LEU A CG  1 
ATOM 859  C CD1 . LEU A 1 187 ? 104.785 114.671 107.521 1.00 89.04  ? 187 LEU A CD1 1 
ATOM 860  C CD2 . LEU A 1 187 ? 105.576 116.981 106.973 1.00 87.24  ? 187 LEU A CD2 1 
ATOM 861  N N   . LEU A 1 188 ? 109.431 117.278 108.353 1.00 79.10  ? 188 LEU A N   1 
ATOM 862  C CA  . LEU A 1 188 ? 110.230 118.147 107.501 1.00 77.25  ? 188 LEU A CA  1 
ATOM 863  C C   . LEU A 1 188 ? 111.618 117.559 107.285 1.00 72.48  ? 188 LEU A C   1 
ATOM 864  O O   . LEU A 1 188 ? 112.162 117.647 106.179 1.00 75.54  ? 188 LEU A O   1 
ATOM 865  C CB  . LEU A 1 188 ? 110.309 119.543 108.119 1.00 76.71  ? 188 LEU A CB  1 
ATOM 866  C CG  . LEU A 1 188 ? 111.037 120.679 107.401 1.00 70.19  ? 188 LEU A CG  1 
ATOM 867  C CD1 . LEU A 1 188 ? 110.784 120.638 105.905 1.00 66.95  ? 188 LEU A CD1 1 
ATOM 868  C CD2 . LEU A 1 188 ? 110.576 122.004 107.960 1.00 62.36  ? 188 LEU A CD2 1 
ATOM 869  N N   . LEU A 1 189 ? 112.195 116.942 108.323 1.00 68.74  ? 189 LEU A N   1 
ATOM 870  C CA  . LEU A 1 189 ? 113.449 116.210 108.167 1.00 69.23  ? 189 LEU A CA  1 
ATOM 871  C C   . LEU A 1 189 ? 113.332 115.124 107.114 1.00 71.52  ? 189 LEU A C   1 
ATOM 872  O O   . LEU A 1 189 ? 114.196 115.001 106.234 1.00 72.99  ? 189 LEU A O   1 
ATOM 873  C CB  . LEU A 1 189 ? 113.869 115.578 109.490 1.00 70.33  ? 189 LEU A CB  1 
ATOM 874  C CG  . LEU A 1 189 ? 115.356 115.590 109.843 1.00 73.98  ? 189 LEU A CG  1 
ATOM 875  C CD1 . LEU A 1 189 ? 116.084 116.814 109.291 1.00 68.60  ? 189 LEU A CD1 1 
ATOM 876  C CD2 . LEU A 1 189 ? 115.569 115.395 111.339 1.00 77.88  ? 189 LEU A CD2 1 
ATOM 877  N N   . ALA A 1 190 ? 112.265 114.324 107.195 1.00 70.70  ? 190 ALA A N   1 
ATOM 878  C CA  . ALA A 1 190 ? 112.065 113.255 106.225 1.00 70.12  ? 190 ALA A CA  1 
ATOM 879  C C   . ALA A 1 190 ? 111.884 113.814 104.822 1.00 69.09  ? 190 ALA A C   1 
ATOM 880  O O   . ALA A 1 190 ? 112.443 113.277 103.858 1.00 73.17  ? 190 ALA A O   1 
ATOM 881  C CB  . ALA A 1 190 ? 110.862 112.402 106.624 1.00 73.33  ? 190 ALA A CB  1 
ATOM 882  N N   . ALA A 1 191 ? 111.142 114.916 104.698 1.00 68.35  ? 191 ALA A N   1 
ATOM 883  C CA  . ALA A 1 191 ? 110.870 115.503 103.391 1.00 72.66  ? 191 ALA A CA  1 
ATOM 884  C C   . ALA A 1 191 ? 112.142 116.023 102.734 1.00 74.95  ? 191 ALA A C   1 
ATOM 885  O O   . ALA A 1 191 ? 112.409 115.726 101.562 1.00 79.54  ? 191 ALA A O   1 
ATOM 886  C CB  . ALA A 1 191 ? 109.836 116.622 103.526 1.00 75.62  ? 191 ALA A CB  1 
ATOM 887  N N   . THR A 1 192 ? 112.955 116.783 103.474 1.00 71.28  ? 192 THR A N   1 
ATOM 888  C CA  . THR A 1 192 ? 114.184 117.294 102.872 1.00 70.46  ? 192 THR A CA  1 
ATOM 889  C C   . THR A 1 192 ? 115.227 116.212 102.647 1.00 69.99  ? 192 THR A C   1 
ATOM 890  O O   . THR A 1 192 ? 115.965 116.286 101.661 1.00 74.47  ? 192 THR A O   1 
ATOM 891  C CB  . THR A 1 192 ? 114.800 118.426 103.689 1.00 72.06  ? 192 THR A CB  1 
ATOM 892  O OG1 . THR A 1 192 ? 115.637 117.893 104.727 1.00 65.13  ? 192 THR A OG1 1 
ATOM 893  C CG2 . THR A 1 192 ? 113.783 119.432 104.185 1.00 74.53  ? 192 THR A CG2 1 
ATOM 894  N N   . TRP A 1 193 ? 115.315 115.207 103.519 1.00 66.62  ? 193 TRP A N   1 
ATOM 895  C CA  . TRP A 1 193 ? 116.273 114.135 103.269 1.00 68.72  ? 193 TRP A CA  1 
ATOM 896  C C   . TRP A 1 193 ? 115.876 113.316 102.043 1.00 74.12  ? 193 TRP A C   1 
ATOM 897  O O   . TRP A 1 193 ? 116.736 112.942 101.233 1.00 75.95  ? 193 TRP A O   1 
ATOM 898  C CB  . TRP A 1 193 ? 116.394 113.255 104.507 1.00 68.82  ? 193 TRP A CB  1 
ATOM 899  C CG  . TRP A 1 193 ? 117.685 113.436 105.242 1.00 68.40  ? 193 TRP A CG  1 
ATOM 900  C CD1 . TRP A 1 193 ? 117.860 114.059 106.439 1.00 68.78  ? 193 TRP A CD1 1 
ATOM 901  C CD2 . TRP A 1 193 ? 118.976 112.975 104.837 1.00 71.29  ? 193 TRP A CD2 1 
ATOM 902  N NE1 . TRP A 1 193 ? 119.180 114.022 106.803 1.00 69.16  ? 193 TRP A NE1 1 
ATOM 903  C CE2 . TRP A 1 193 ? 119.887 113.360 105.837 1.00 67.85  ? 193 TRP A CE2 1 
ATOM 904  C CE3 . TRP A 1 193 ? 119.451 112.273 103.727 1.00 78.59  ? 193 TRP A CE3 1 
ATOM 905  C CZ2 . TRP A 1 193 ? 121.246 113.071 105.759 1.00 72.06  ? 193 TRP A CZ2 1 
ATOM 906  C CZ3 . TRP A 1 193 ? 120.801 111.987 103.650 1.00 82.69  ? 193 TRP A CZ3 1 
ATOM 907  C CH2 . TRP A 1 193 ? 121.683 112.385 104.661 1.00 79.50  ? 193 TRP A CH2 1 
ATOM 908  N N   . THR A 1 194 ? 114.573 113.065 101.867 1.00 76.30  ? 194 THR A N   1 
ATOM 909  C CA  . THR A 1 194 ? 114.112 112.336 100.690 1.00 74.81  ? 194 THR A CA  1 
ATOM 910  C C   . THR A 1 194 ? 114.283 113.157 99.419  1.00 75.23  ? 194 THR A C   1 
ATOM 911  O O   . THR A 1 194 ? 114.659 112.613 98.373  1.00 82.28  ? 194 THR A O   1 
ATOM 912  C CB  . THR A 1 194 ? 112.654 111.920 100.861 1.00 73.15  ? 194 THR A CB  1 
ATOM 913  O OG1 . THR A 1 194 ? 111.910 113.006 101.426 1.00 74.61  ? 194 THR A OG1 1 
ATOM 914  C CG2 . THR A 1 194 ? 112.550 110.705 101.771 1.00 73.67  ? 194 THR A CG2 1 
ATOM 915  N N   . VAL A 1 195 ? 114.023 114.467 99.480  1.00 71.12  ? 195 VAL A N   1 
ATOM 916  C CA  . VAL A 1 195 ? 114.239 115.285 98.294  1.00 73.15  ? 195 VAL A CA  1 
ATOM 917  C C   . VAL A 1 195 ? 115.727 115.467 98.013  1.00 74.71  ? 195 VAL A C   1 
ATOM 918  O O   . VAL A 1 195 ? 116.111 115.648 96.854  1.00 77.25  ? 195 VAL A O   1 
ATOM 919  C CB  . VAL A 1 195 ? 113.492 116.632 98.406  1.00 74.74  ? 195 VAL A CB  1 
ATOM 920  C CG1 . VAL A 1 195 ? 114.306 117.685 99.144  1.00 76.29  ? 195 VAL A CG1 1 
ATOM 921  C CG2 . VAL A 1 195 ? 113.098 117.131 97.026  1.00 75.43  ? 195 VAL A CG2 1 
ATOM 922  N N   . SER A 1 196 ? 116.586 115.352 99.031  1.00 71.18  ? 196 SER A N   1 
ATOM 923  C CA  . SER A 1 196 ? 118.022 115.371 98.789  1.00 71.73  ? 196 SER A CA  1 
ATOM 924  C C   . SER A 1 196 ? 118.474 114.095 98.096  1.00 74.44  ? 196 SER A C   1 
ATOM 925  O O   . SER A 1 196 ? 119.293 114.143 97.171  1.00 75.87  ? 196 SER A O   1 
ATOM 926  C CB  . SER A 1 196 ? 118.773 115.558 100.105 1.00 70.74  ? 196 SER A CB  1 
ATOM 927  O OG  . SER A 1 196 ? 118.699 114.389 100.900 1.00 74.46  ? 196 SER A OG  1 
ATOM 928  N N   . LEU A 1 197 ? 117.943 112.949 98.527  1.00 75.63  ? 197 LEU A N   1 
ATOM 929  C CA  . LEU A 1 197 ? 118.237 111.694 97.838  1.00 76.79  ? 197 LEU A CA  1 
ATOM 930  C C   . LEU A 1 197 ? 117.726 111.721 96.404  1.00 76.51  ? 197 LEU A C   1 
ATOM 931  O O   . LEU A 1 197 ? 118.400 111.234 95.491  1.00 79.06  ? 197 LEU A O   1 
ATOM 932  C CB  . LEU A 1 197 ? 117.636 110.510 98.598  1.00 82.62  ? 197 LEU A CB  1 
ATOM 933  C CG  . LEU A 1 197 ? 118.505 109.742 99.602  1.00 86.46  ? 197 LEU A CG  1 
ATOM 934  C CD1 . LEU A 1 197 ? 119.449 108.804 98.863  1.00 88.10  ? 197 LEU A CD1 1 
ATOM 935  C CD2 . LEU A 1 197 ? 119.290 110.658 100.525 1.00 80.16  ? 197 LEU A CD2 1 
ATOM 936  N N   . GLY A 1 198 ? 116.549 112.306 96.185  1.00 76.18  ? 198 GLY A N   1 
ATOM 937  C CA  . GLY A 1 198 ? 116.028 112.422 94.832  1.00 80.93  ? 198 GLY A CA  1 
ATOM 938  C C   . GLY A 1 198 ? 116.858 113.340 93.954  1.00 81.66  ? 198 GLY A C   1 
ATOM 939  O O   . GLY A 1 198 ? 117.098 113.039 92.782  1.00 81.83  ? 198 GLY A O   1 
ATOM 940  N N   . LEU A 1 199 ? 117.312 114.468 94.508  1.00 78.95  ? 199 LEU A N   1 
ATOM 941  C CA  . LEU A 1 199 ? 118.149 115.389 93.747  1.00 78.95  ? 199 LEU A CA  1 
ATOM 942  C C   . LEU A 1 199 ? 119.503 114.770 93.426  1.00 84.82  ? 199 LEU A C   1 
ATOM 943  O O   . LEU A 1 199 ? 120.056 114.999 92.344  1.00 88.52  ? 199 LEU A O   1 
ATOM 944  C CB  . LEU A 1 199 ? 118.326 116.694 94.520  1.00 72.51  ? 199 LEU A CB  1 
ATOM 945  C CG  . LEU A 1 199 ? 117.268 117.760 94.253  1.00 70.03  ? 199 LEU A CG  1 
ATOM 946  C CD1 . LEU A 1 199 ? 117.588 119.038 95.011  1.00 71.54  ? 199 LEU A CD1 1 
ATOM 947  C CD2 . LEU A 1 199 ? 117.156 118.026 92.768  1.00 71.40  ? 199 LEU A CD2 1 
ATOM 948  N N   . GLY A 1 200 ? 120.057 113.994 94.359  1.00 83.29  ? 200 GLY A N   1 
ATOM 949  C CA  . GLY A 1 200 ? 121.294 113.288 94.077  1.00 78.86  ? 200 GLY A CA  1 
ATOM 950  C C   . GLY A 1 200 ? 121.120 112.183 93.054  1.00 83.01  ? 200 GLY A C   1 
ATOM 951  O O   . GLY A 1 200 ? 122.008 111.943 92.231  1.00 83.74  ? 200 GLY A O   1 
ATOM 952  N N   . LEU A 1 201 ? 119.984 111.487 93.095  1.00 83.18  ? 201 LEU A N   1 
ATOM 953  C CA  . LEU A 1 201 ? 119.750 110.363 92.201  1.00 85.70  ? 201 LEU A CA  1 
ATOM 954  C C   . LEU A 1 201 ? 119.245 110.785 90.832  1.00 86.56  ? 201 LEU A C   1 
ATOM 955  O O   . LEU A 1 201 ? 119.210 109.948 89.925  1.00 90.65  ? 201 LEU A O   1 
ATOM 956  C CB  . LEU A 1 201 ? 118.751 109.393 92.836  1.00 89.24  ? 201 LEU A CB  1 
ATOM 957  C CG  . LEU A 1 201 ? 119.240 107.986 93.194  1.00 95.14  ? 201 LEU A CG  1 
ATOM 958  C CD1 . LEU A 1 201 ? 118.059 107.046 93.380  1.00 94.52  ? 201 LEU A CD1 1 
ATOM 959  C CD2 . LEU A 1 201 ? 120.195 107.442 92.141  1.00 89.28  ? 201 LEU A CD2 1 
ATOM 960  N N   . LEU A 1 202 ? 118.831 112.042 90.675  1.00 83.63  ? 202 LEU A N   1 
ATOM 961  C CA  . LEU A 1 202 ? 118.373 112.522 89.372  1.00 86.02  ? 202 LEU A CA  1 
ATOM 962  C C   . LEU A 1 202 ? 119.433 112.457 88.270  1.00 87.48  ? 202 LEU A C   1 
ATOM 963  O O   . LEU A 1 202 ? 119.091 112.009 87.162  1.00 91.69  ? 202 LEU A O   1 
ATOM 964  C CB  . LEU A 1 202 ? 117.791 113.934 89.521  1.00 83.08  ? 202 LEU A CB  1 
ATOM 965  C CG  . LEU A 1 202 ? 117.115 114.534 88.287  1.00 81.23  ? 202 LEU A CG  1 
ATOM 966  C CD1 . LEU A 1 202 ? 116.063 113.587 87.734  1.00 79.76  ? 202 LEU A CD1 1 
ATOM 967  C CD2 . LEU A 1 202 ? 116.503 115.884 88.615  1.00 78.76  ? 202 LEU A CD2 1 
ATOM 968  N N   . PRO A 1 203 ? 120.695 112.877 88.464  1.00 85.76  ? 203 PRO A N   1 
ATOM 969  C CA  . PRO A 1 203 ? 121.656 112.706 87.362  1.00 88.20  ? 203 PRO A CA  1 
ATOM 970  C C   . PRO A 1 203 ? 122.042 111.263 87.118  1.00 90.54  ? 203 PRO A C   1 
ATOM 971  O O   . PRO A 1 203 ? 122.371 110.910 85.979  1.00 92.73  ? 203 PRO A O   1 
ATOM 972  C CB  . PRO A 1 203 ? 122.865 113.540 87.806  1.00 91.54  ? 203 PRO A CB  1 
ATOM 973  C CG  . PRO A 1 203 ? 122.335 114.463 88.821  1.00 90.74  ? 203 PRO A CG  1 
ATOM 974  C CD  . PRO A 1 203 ? 121.313 113.672 89.543  1.00 88.28  ? 203 PRO A CD  1 
ATOM 975  N N   . VAL A 1 204 ? 122.023 110.420 88.153  1.00 91.86  ? 204 VAL A N   1 
ATOM 976  C CA  . VAL A 1 204 ? 122.324 109.005 87.962  1.00 95.75  ? 204 VAL A CA  1 
ATOM 977  C C   . VAL A 1 204 ? 121.212 108.324 87.178  1.00 92.49  ? 204 VAL A C   1 
ATOM 978  O O   . VAL A 1 204 ? 121.466 107.395 86.404  1.00 89.44  ? 204 VAL A O   1 
ATOM 979  C CB  . VAL A 1 204 ? 122.560 108.318 89.319  1.00 96.99  ? 204 VAL A CB  1 
ATOM 980  C CG1 . VAL A 1 204 ? 123.345 107.028 89.133  1.00 87.85  ? 204 VAL A CG1 1 
ATOM 981  C CG2 . VAL A 1 204 ? 123.285 109.257 90.271  1.00 92.49  ? 204 VAL A CG2 1 
ATOM 982  N N   . LEU A 1 205 ? 119.969 108.774 87.358  1.00 92.21  ? 205 LEU A N   1 
ATOM 983  C CA  . LEU A 1 205 ? 118.840 108.175 86.659  1.00 95.92  ? 205 LEU A CA  1 
ATOM 984  C C   . LEU A 1 205 ? 118.847 108.474 85.167  1.00 94.84  ? 205 LEU A C   1 
ATOM 985  O O   . LEU A 1 205 ? 118.194 107.756 84.403  1.00 99.36  ? 205 LEU A O   1 
ATOM 986  C CB  . LEU A 1 205 ? 117.526 108.659 87.275  1.00 100.26 ? 205 LEU A CB  1 
ATOM 987  C CG  . LEU A 1 205 ? 116.450 107.597 87.515  1.00 105.36 ? 205 LEU A CG  1 
ATOM 988  C CD1 . LEU A 1 205 ? 117.007 106.436 88.325  1.00 103.95 ? 205 LEU A CD1 1 
ATOM 989  C CD2 . LEU A 1 205 ? 115.239 108.206 88.205  1.00 100.66 ? 205 LEU A CD2 1 
ATOM 990  N N   . GLY A 1 206 ? 119.563 109.506 84.732  1.00 89.74  ? 206 GLY A N   1 
ATOM 991  C CA  . GLY A 1 206 ? 119.625 109.805 83.318  1.00 92.17  ? 206 GLY A CA  1 
ATOM 992  C C   . GLY A 1 206 ? 119.555 111.281 82.992  1.00 96.63  ? 206 GLY A C   1 
ATOM 993  O O   . GLY A 1 206 ? 119.655 111.667 81.823  1.00 100.04 ? 206 GLY A O   1 
ATOM 994  N N   . TRP A 1 207 ? 119.383 112.119 84.010  1.00 96.01  ? 207 TRP A N   1 
ATOM 995  C CA  . TRP A 1 207 ? 119.383 113.571 83.821  1.00 92.42  ? 207 TRP A CA  1 
ATOM 996  C C   . TRP A 1 207 ? 120.787 114.142 83.989  1.00 88.11  ? 207 TRP A C   1 
ATOM 997  O O   . TRP A 1 207 ? 121.025 115.090 84.735  1.00 88.33  ? 207 TRP A O   1 
ATOM 998  C CB  . TRP A 1 207 ? 118.398 114.219 84.787  1.00 91.40  ? 207 TRP A CB  1 
ATOM 999  C CG  . TRP A 1 207 ? 117.986 115.620 84.428  1.00 86.77  ? 207 TRP A CG  1 
ATOM 1000 C CD1 . TRP A 1 207 ? 118.162 116.739 85.184  1.00 81.34  ? 207 TRP A CD1 1 
ATOM 1001 C CD2 . TRP A 1 207 ? 117.315 116.045 83.234  1.00 89.42  ? 207 TRP A CD2 1 
ATOM 1002 N NE1 . TRP A 1 207 ? 117.654 117.834 84.536  1.00 79.14  ? 207 TRP A NE1 1 
ATOM 1003 C CE2 . TRP A 1 207 ? 117.127 117.435 83.337  1.00 87.78  ? 207 TRP A CE2 1 
ATOM 1004 C CE3 . TRP A 1 207 ? 116.856 115.385 82.089  1.00 94.18  ? 207 TRP A CE3 1 
ATOM 1005 C CZ2 . TRP A 1 207 ? 116.500 118.179 82.338  1.00 95.19  ? 207 TRP A CZ2 1 
ATOM 1006 C CZ3 . TRP A 1 207 ? 116.237 116.125 81.099  1.00 98.22  ? 207 TRP A CZ3 1 
ATOM 1007 C CH2 . TRP A 1 207 ? 116.065 117.507 81.230  1.00 99.16  ? 207 TRP A CH2 1 
ATOM 1008 N N   . ASN A 1 208 ? 121.731 113.549 83.275  1.00 86.47  ? 208 ASN A N   1 
ATOM 1009 C CA  . ASN A 1 208 ? 123.132 113.923 83.309  1.00 88.65  ? 208 ASN A CA  1 
ATOM 1010 C C   . ASN A 1 208 ? 123.509 114.574 81.985  1.00 91.09  ? 208 ASN A C   1 
ATOM 1011 O O   . ASN A 1 208 ? 122.662 114.816 81.122  1.00 91.55  ? 208 ASN A O   1 
ATOM 1012 C CB  . ASN A 1 208 ? 123.997 112.697 83.623  1.00 94.60  ? 208 ASN A CB  1 
ATOM 1013 C CG  . ASN A 1 208 ? 124.259 111.828 82.404  1.00 99.11  ? 208 ASN A CG  1 
ATOM 1014 O OD1 . ASN A 1 208 ? 125.192 112.071 81.640  1.00 98.05  ? 208 ASN A OD1 1 
ATOM 1015 N ND2 . ASN A 1 208 ? 123.430 110.806 82.219  1.00 100.04 ? 208 ASN A ND2 1 
ATOM 1016 N N   . CYS A 1 209 ? 124.797 114.864 81.829  1.00 92.44  ? 209 CYS A N   1 
ATOM 1017 C CA  . CYS A 1 209 ? 125.312 115.525 80.633  1.00 96.07  ? 209 CYS A CA  1 
ATOM 1018 C C   . CYS A 1 209 ? 126.434 114.677 80.045  1.00 98.96  ? 209 CYS A C   1 
ATOM 1019 O O   . CYS A 1 209 ? 127.614 114.913 80.314  1.00 103.77 ? 209 CYS A O   1 
ATOM 1020 C CB  . CYS A 1 209 ? 125.787 116.923 80.977  1.00 99.31  ? 209 CYS A CB  1 
ATOM 1021 S SG  . CYS A 1 209 ? 125.933 118.017 79.565  1.00 115.60 ? 209 CYS A SG  1 
ATOM 1022 N N   . LEU A 1 210 ? 126.064 113.687 79.237  1.00 95.74  ? 210 LEU A N   1 
ATOM 1023 C CA  . LEU A 1 210 ? 127.045 112.891 78.510  1.00 98.97  ? 210 LEU A CA  1 
ATOM 1024 C C   . LEU A 1 210 ? 126.862 112.967 77.004  1.00 96.23  ? 210 LEU A C   1 
ATOM 1025 O O   . LEU A 1 210 ? 127.806 113.313 76.286  1.00 93.83  ? 210 LEU A O   1 
ATOM 1026 C CB  . LEU A 1 210 ? 126.988 111.426 78.970  1.00 102.55 ? 210 LEU A CB  1 
ATOM 1027 C CG  . LEU A 1 210 ? 127.964 111.034 80.081  1.00 99.66  ? 210 LEU A CG  1 
ATOM 1028 C CD1 . LEU A 1 210 ? 127.787 109.574 80.467  1.00 96.48  ? 210 LEU A CD1 1 
ATOM 1029 C CD2 . LEU A 1 210 ? 129.399 111.311 79.660  1.00 95.91  ? 210 LEU A CD2 1 
ATOM 1030 N N   . ALA A 1 211 ? 125.668 112.652 76.502  1.00 95.61  ? 211 ALA A N   1 
ATOM 1031 C CA  . ALA A 1 211 ? 125.448 112.683 75.061  1.00 100.43 ? 211 ALA A CA  1 
ATOM 1032 C C   . ALA A 1 211 ? 125.337 114.112 74.554  1.00 106.36 ? 211 ALA A C   1 
ATOM 1033 O O   . ALA A 1 211 ? 125.889 114.449 73.501  1.00 109.34 ? 211 ALA A O   1 
ATOM 1034 C CB  . ALA A 1 211 ? 124.195 111.884 74.704  1.00 102.13 ? 211 ALA A CB  1 
ATOM 1035 N N   . GLU A 1 212 ? 124.635 114.969 75.294  1.00 110.09 ? 212 GLU A N   1 
ATOM 1036 C CA  . GLU A 1 212 ? 124.493 116.378 74.935  1.00 116.64 ? 212 GLU A CA  1 
ATOM 1037 C C   . GLU A 1 212 ? 125.696 117.149 75.480  1.00 119.97 ? 212 GLU A C   1 
ATOM 1038 O O   . GLU A 1 212 ? 125.597 117.968 76.395  1.00 118.39 ? 212 GLU A O   1 
ATOM 1039 C CB  . GLU A 1 212 ? 123.180 116.930 75.469  1.00 117.35 ? 212 GLU A CB  1 
ATOM 1040 C CG  . GLU A 1 212 ? 121.981 116.050 75.172  1.00 118.61 ? 212 GLU A CG  1 
ATOM 1041 C CD  . GLU A 1 212 ? 121.744 115.872 73.686  1.00 118.39 ? 212 GLU A CD  1 
ATOM 1042 O OE1 . GLU A 1 212 ? 121.775 116.882 72.952  1.00 116.00 ? 212 GLU A OE1 1 
ATOM 1043 O OE2 . GLU A 1 212 ? 121.529 114.722 73.251  1.00 117.59 ? 212 GLU A OE2 1 
ATOM 1044 N N   . ARG A 1 213 ? 126.857 116.872 74.876  1.00 121.59 ? 213 ARG A N   1 
ATOM 1045 C CA  . ARG A 1 213 ? 128.131 117.365 75.390  1.00 127.16 ? 213 ARG A CA  1 
ATOM 1046 C C   . ARG A 1 213 ? 128.278 118.878 75.279  1.00 130.53 ? 213 ARG A C   1 
ATOM 1047 O O   . ARG A 1 213 ? 129.094 119.460 76.001  1.00 127.39 ? 213 ARG A O   1 
ATOM 1048 C CB  . ARG A 1 213 ? 129.286 116.680 74.658  1.00 122.17 ? 213 ARG A CB  1 
ATOM 1049 N N   . ALA A 1 214 ? 127.516 119.526 74.396  1.00 130.44 ? 214 ALA A N   1 
ATOM 1050 C CA  . ALA A 1 214 ? 127.618 120.975 74.263  1.00 125.26 ? 214 ALA A CA  1 
ATOM 1051 C C   . ALA A 1 214 ? 126.957 121.691 75.436  1.00 122.81 ? 214 ALA A C   1 
ATOM 1052 O O   . ALA A 1 214 ? 127.494 122.680 75.948  1.00 117.42 ? 214 ALA A O   1 
ATOM 1053 C CB  . ALA A 1 214 ? 126.998 121.426 72.941  1.00 119.75 ? 214 ALA A CB  1 
ATOM 1054 N N   . ALA A 1 215 ? 125.799 121.209 75.876  1.00 122.41 ? 215 ALA A N   1 
ATOM 1055 C CA  . ALA A 1 215 ? 125.028 121.872 76.928  1.00 115.86 ? 215 ALA A CA  1 
ATOM 1056 C C   . ALA A 1 215 ? 125.328 121.259 78.295  1.00 106.83 ? 215 ALA A C   1 
ATOM 1057 O O   . ALA A 1 215 ? 124.442 120.783 79.002  1.00 97.75  ? 215 ALA A O   1 
ATOM 1058 C CB  . ALA A 1 215 ? 123.538 121.809 76.606  1.00 116.65 ? 215 ALA A CB  1 
ATOM 1059 N N   . CYS A 1 216 ? 126.602 121.294 78.669  1.00 105.46 ? 216 CYS A N   1 
ATOM 1060 C CA  . CYS A 1 216 ? 127.060 120.782 79.951  1.00 102.61 ? 216 CYS A CA  1 
ATOM 1061 C C   . CYS A 1 216 ? 127.370 121.938 80.892  1.00 95.69  ? 216 CYS A C   1 
ATOM 1062 O O   . CYS A 1 216 ? 127.702 123.043 80.456  1.00 99.46  ? 216 CYS A O   1 
ATOM 1063 C CB  . CYS A 1 216 ? 128.299 119.899 79.781  1.00 110.21 ? 216 CYS A CB  1 
ATOM 1064 S SG  . CYS A 1 216 ? 127.932 118.205 79.264  1.00 130.66 ? 216 CYS A SG  1 
ATOM 1065 N N   . SER A 1 217 ? 127.259 121.673 82.191  1.00 91.59  ? 217 SER A N   1 
ATOM 1066 C CA  . SER A 1 217 ? 127.428 122.708 83.196  1.00 88.98  ? 217 SER A CA  1 
ATOM 1067 C C   . SER A 1 217 ? 128.887 122.799 83.638  1.00 83.69  ? 217 SER A C   1 
ATOM 1068 O O   . SER A 1 217 ? 129.760 122.069 83.163  1.00 81.83  ? 217 SER A O   1 
ATOM 1069 C CB  . SER A 1 217 ? 126.512 122.449 84.388  1.00 86.63  ? 217 SER A CB  1 
ATOM 1070 O OG  . SER A 1 217 ? 126.511 123.551 85.279  1.00 83.78  ? 217 SER A OG  1 
ATOM 1071 N N   . VAL A 1 218 ? 129.152 123.710 84.575  1.00 75.84  ? 218 VAL A N   1 
ATOM 1072 C CA  . VAL A 1 218 ? 130.524 123.968 84.988  1.00 73.01  ? 218 VAL A CA  1 
ATOM 1073 C C   . VAL A 1 218 ? 131.053 122.910 85.945  1.00 72.29  ? 218 VAL A C   1 
ATOM 1074 O O   . VAL A 1 218 ? 132.269 122.829 86.151  1.00 74.96  ? 218 VAL A O   1 
ATOM 1075 C CB  . VAL A 1 218 ? 130.634 125.371 85.608  1.00 78.95  ? 218 VAL A CB  1 
ATOM 1076 C CG1 . VAL A 1 218 ? 129.849 126.370 84.779  1.00 83.37  ? 218 VAL A CG1 1 
ATOM 1077 C CG2 . VAL A 1 218 ? 130.137 125.379 87.042  1.00 81.23  ? 218 VAL A CG2 1 
ATOM 1078 N N   . VAL A 1 219 ? 130.185 122.095 86.534  1.00 74.34  ? 219 VAL A N   1 
ATOM 1079 C CA  . VAL A 1 219 ? 130.599 120.992 87.391  1.00 77.12  ? 219 VAL A CA  1 
ATOM 1080 C C   . VAL A 1 219 ? 130.307 119.713 86.621  1.00 81.72  ? 219 VAL A C   1 
ATOM 1081 O O   . VAL A 1 219 ? 129.169 119.240 86.591  1.00 85.59  ? 219 VAL A O   1 
ATOM 1082 C CB  . VAL A 1 219 ? 129.884 121.015 88.744  1.00 76.87  ? 219 VAL A CB  1 
ATOM 1083 C CG1 . VAL A 1 219 ? 130.619 120.132 89.743  1.00 77.85  ? 219 VAL A CG1 1 
ATOM 1084 C CG2 . VAL A 1 219 ? 129.778 122.434 89.269  1.00 79.37  ? 219 VAL A CG2 1 
ATOM 1085 N N   . ARG A 1 220 ? 131.333 119.160 85.982  1.00 78.69  ? 220 ARG A N   1 
ATOM 1086 C CA  . ARG A 1 220 ? 131.171 117.944 85.210  1.00 78.14  ? 220 ARG A CA  1 
ATOM 1087 C C   . ARG A 1 220 ? 130.916 116.766 86.147  1.00 80.40  ? 220 ARG A C   1 
ATOM 1088 O O   . ARG A 1 220 ? 131.479 116.702 87.241  1.00 82.78  ? 220 ARG A O   1 
ATOM 1089 C CB  . ARG A 1 220 ? 132.421 117.690 84.367  1.00 77.87  ? 220 ARG A CB  1 
ATOM 1090 C CG  . ARG A 1 220 ? 132.732 118.707 83.244  1.00 82.02  ? 220 ARG A CG  1 
ATOM 1091 C CD  . ARG A 1 220 ? 131.630 119.117 82.234  1.00 91.83  ? 220 ARG A CD  1 
ATOM 1092 N NE  . ARG A 1 220 ? 130.484 118.228 82.078  1.00 96.39  ? 220 ARG A NE  1 
ATOM 1093 C CZ  . ARG A 1 220 ? 130.496 117.118 81.352  1.00 100.32 ? 220 ARG A CZ  1 
ATOM 1094 N NH1 . ARG A 1 220 ? 131.591 116.711 80.731  1.00 99.62  ? 220 ARG A NH1 1 
ATOM 1095 N NH2 . ARG A 1 220 ? 129.378 116.408 81.231  1.00 101.76 ? 220 ARG A NH2 1 
ATOM 1096 N N   . PRO A 1 221 ? 130.066 115.814 85.742  1.00 80.46  ? 221 PRO A N   1 
ATOM 1097 C CA  . PRO A 1 221 ? 129.322 115.717 84.488  1.00 81.59  ? 221 PRO A CA  1 
ATOM 1098 C C   . PRO A 1 221 ? 127.873 116.170 84.604  1.00 85.64  ? 221 PRO A C   1 
ATOM 1099 O O   . PRO A 1 221 ? 127.018 115.681 83.875  1.00 87.49  ? 221 PRO A O   1 
ATOM 1100 C CB  . PRO A 1 221 ? 129.417 114.223 84.173  1.00 87.31  ? 221 PRO A CB  1 
ATOM 1101 C CG  . PRO A 1 221 ? 129.426 113.554 85.545  1.00 86.95  ? 221 PRO A CG  1 
ATOM 1102 C CD  . PRO A 1 221 ? 129.881 114.600 86.552  1.00 84.75  ? 221 PRO A CD  1 
ATOM 1103 N N   . LEU A 1 222 ? 127.567 117.097 85.506  1.00 87.74  ? 222 LEU A N   1 
ATOM 1104 C CA  . LEU A 1 222 ? 126.197 117.546 85.697  1.00 84.76  ? 222 LEU A CA  1 
ATOM 1105 C C   . LEU A 1 222 ? 125.751 118.453 84.558  1.00 85.61  ? 222 LEU A C   1 
ATOM 1106 O O   . LEU A 1 222 ? 126.559 119.129 83.917  1.00 90.41  ? 222 LEU A O   1 
ATOM 1107 C CB  . LEU A 1 222 ? 126.055 118.288 87.021  1.00 82.07  ? 222 LEU A CB  1 
ATOM 1108 C CG  . LEU A 1 222 ? 126.270 117.477 88.293  1.00 84.15  ? 222 LEU A CG  1 
ATOM 1109 C CD1 . LEU A 1 222 ? 125.792 118.275 89.484  1.00 86.62  ? 222 LEU A CD1 1 
ATOM 1110 C CD2 . LEU A 1 222 ? 125.544 116.151 88.207  1.00 85.43  ? 222 LEU A CD2 1 
ATOM 1111 N N   . ALA A 1 223 ? 124.444 118.464 84.315  1.00 84.63  ? 223 ALA A N   1 
ATOM 1112 C CA  . ALA A 1 223 ? 123.870 119.277 83.258  1.00 84.62  ? 223 ALA A CA  1 
ATOM 1113 C C   . ALA A 1 223 ? 123.544 120.674 83.775  1.00 77.19  ? 223 ALA A C   1 
ATOM 1114 O O   . ALA A 1 223 ? 123.608 120.954 84.974  1.00 75.48  ? 223 ALA A O   1 
ATOM 1115 C CB  . ALA A 1 223 ? 122.617 118.612 82.690  1.00 82.67  ? 223 ALA A CB  1 
ATOM 1116 N N   . ARG A 1 224 ? 123.192 121.560 82.843  1.00 75.05  ? 224 ARG A N   1 
ATOM 1117 C CA  . ARG A 1 224 ? 122.882 122.941 83.192  1.00 68.40  ? 224 ARG A CA  1 
ATOM 1118 C C   . ARG A 1 224 ? 121.566 123.046 83.948  1.00 61.52  ? 224 ARG A C   1 
ATOM 1119 O O   . ARG A 1 224 ? 121.454 123.813 84.911  1.00 67.19  ? 224 ARG A O   1 
ATOM 1120 C CB  . ARG A 1 224 ? 122.833 123.800 81.929  1.00 71.84  ? 224 ARG A CB  1 
ATOM 1121 C CG  . ARG A 1 224 ? 122.618 125.276 82.193  1.00 71.61  ? 224 ARG A CG  1 
ATOM 1122 C CD  . ARG A 1 224 ? 122.413 126.038 80.899  1.00 78.28  ? 224 ARG A CD  1 
ATOM 1123 N NE  . ARG A 1 224 ? 123.620 126.070 80.084  1.00 85.60  ? 224 ARG A NE  1 
ATOM 1124 C CZ  . ARG A 1 224 ? 124.607 126.942 80.239  1.00 88.67  ? 224 ARG A CZ  1 
ATOM 1125 N NH1 . ARG A 1 224 ? 124.562 127.879 81.171  1.00 88.40  ? 224 ARG A NH1 1 
ATOM 1126 N NH2 . ARG A 1 224 ? 125.665 126.873 79.436  1.00 86.91  ? 224 ARG A NH2 1 
ATOM 1127 N N   . SER A 1 225 ? 120.562 122.279 83.523  1.00 55.18  ? 225 SER A N   1 
ATOM 1128 C CA  . SER A 1 225 ? 119.227 122.411 84.095  1.00 60.84  ? 225 SER A CA  1 
ATOM 1129 C C   . SER A 1 225 ? 119.182 121.927 85.537  1.00 61.99  ? 225 SER A C   1 
ATOM 1130 O O   . SER A 1 225 ? 118.583 122.581 86.400  1.00 63.15  ? 225 SER A O   1 
ATOM 1131 C CB  . SER A 1 225 ? 118.224 121.642 83.240  1.00 69.14  ? 225 SER A CB  1 
ATOM 1132 O OG  . SER A 1 225 ? 118.740 120.371 82.893  1.00 77.05  ? 225 SER A OG  1 
ATOM 1133 N N   . HIS A 1 226 ? 119.808 120.783 85.818  1.00 61.98  ? 226 HIS A N   1 
ATOM 1134 C CA  . HIS A 1 226 ? 119.808 120.250 87.176  1.00 64.92  ? 226 HIS A CA  1 
ATOM 1135 C C   . HIS A 1 226 ? 120.605 121.145 88.114  1.00 64.79  ? 226 HIS A C   1 
ATOM 1136 O O   . HIS A 1 226 ? 120.223 121.347 89.276  1.00 70.09  ? 226 HIS A O   1 
ATOM 1137 C CB  . HIS A 1 226 ? 120.367 118.829 87.169  1.00 69.21  ? 226 HIS A CB  1 
ATOM 1138 C CG  . HIS A 1 226 ? 120.784 118.334 88.518  1.00 77.00  ? 226 HIS A CG  1 
ATOM 1139 N ND1 . HIS A 1 226 ? 122.103 118.144 88.865  1.00 79.08  ? 226 HIS A ND1 1 
ATOM 1140 C CD2 . HIS A 1 226 ? 120.055 117.985 89.603  1.00 78.08  ? 226 HIS A CD2 1 
ATOM 1141 C CE1 . HIS A 1 226 ? 122.170 117.706 90.109  1.00 79.89  ? 226 HIS A CE1 1 
ATOM 1142 N NE2 . HIS A 1 226 ? 120.941 117.598 90.579  1.00 79.35  ? 226 HIS A NE2 1 
ATOM 1143 N N   . VAL A 1 227 ? 121.705 121.710 87.616  1.00 60.06  ? 227 VAL A N   1 
ATOM 1144 C CA  . VAL A 1 227 ? 122.520 122.616 88.416  1.00 59.61  ? 227 VAL A CA  1 
ATOM 1145 C C   . VAL A 1 227 ? 121.753 123.898 88.714  1.00 58.02  ? 227 VAL A C   1 
ATOM 1146 O O   . VAL A 1 227 ? 121.795 124.417 89.838  1.00 59.47  ? 227 VAL A O   1 
ATOM 1147 C CB  . VAL A 1 227 ? 123.855 122.873 87.693  1.00 66.69  ? 227 VAL A CB  1 
ATOM 1148 C CG1 . VAL A 1 227 ? 124.454 124.202 88.073  1.00 68.54  ? 227 VAL A CG1 1 
ATOM 1149 C CG2 . VAL A 1 227 ? 124.835 121.752 87.992  1.00 72.66  ? 227 VAL A CG2 1 
ATOM 1150 N N   . ALA A 1 228 ? 121.013 124.410 87.727  1.00 58.55  ? 228 ALA A N   1 
ATOM 1151 C CA  . ALA A 1 228 ? 120.194 125.596 87.952  1.00 58.60  ? 228 ALA A CA  1 
ATOM 1152 C C   . ALA A 1 228 ? 119.050 125.316 88.915  1.00 57.54  ? 228 ALA A C   1 
ATOM 1153 O O   . ALA A 1 228 ? 118.673 126.197 89.694  1.00 62.47  ? 228 ALA A O   1 
ATOM 1154 C CB  . ALA A 1 228 ? 119.654 126.126 86.626  1.00 59.49  ? 228 ALA A CB  1 
ATOM 1155 N N   . LEU A 1 229 ? 118.491 124.105 88.878  1.00 56.20  ? 229 LEU A N   1 
ATOM 1156 C CA  . LEU A 1 229 ? 117.472 123.725 89.851  1.00 54.92  ? 229 LEU A CA  1 
ATOM 1157 C C   . LEU A 1 229 ? 118.048 123.681 91.261  1.00 53.22  ? 229 LEU A C   1 
ATOM 1158 O O   . LEU A 1 229 ? 117.411 124.149 92.215  1.00 58.61  ? 229 LEU A O   1 
ATOM 1159 C CB  . LEU A 1 229 ? 116.869 122.376 89.468  1.00 56.25  ? 229 LEU A CB  1 
ATOM 1160 C CG  . LEU A 1 229 ? 116.151 121.548 90.531  1.00 55.14  ? 229 LEU A CG  1 
ATOM 1161 C CD1 . LEU A 1 229 ? 114.845 122.210 90.943  1.00 58.46  ? 229 LEU A CD1 1 
ATOM 1162 C CD2 . LEU A 1 229 ? 115.893 120.154 89.997  1.00 53.90  ? 229 LEU A CD2 1 
ATOM 1163 N N   . LEU A 1 230 ? 119.262 123.143 91.404  1.00 50.36  ? 230 LEU A N   1 
ATOM 1164 C CA  . LEU A 1 230 ? 119.943 123.149 92.696  1.00 53.83  ? 230 LEU A CA  1 
ATOM 1165 C C   . LEU A 1 230 ? 120.199 124.569 93.190  1.00 59.27  ? 230 LEU A C   1 
ATOM 1166 O O   . LEU A 1 230 ? 119.985 124.873 94.372  1.00 65.04  ? 230 LEU A O   1 
ATOM 1167 C CB  . LEU A 1 230 ? 121.262 122.391 92.589  1.00 61.39  ? 230 LEU A CB  1 
ATOM 1168 C CG  . LEU A 1 230 ? 121.383 121.029 93.268  1.00 71.06  ? 230 LEU A CG  1 
ATOM 1169 C CD1 . LEU A 1 230 ? 122.841 120.622 93.308  1.00 71.80  ? 230 LEU A CD1 1 
ATOM 1170 C CD2 . LEU A 1 230 ? 120.792 121.060 94.667  1.00 66.22  ? 230 LEU A CD2 1 
ATOM 1171 N N   . SER A 1 231 ? 120.649 125.451 92.295  1.00 59.38  ? 231 SER A N   1 
ATOM 1172 C CA  . SER A 1 231 ? 120.941 126.831 92.676  1.00 60.82  ? 231 SER A CA  1 
ATOM 1173 C C   . SER A 1 231 ? 119.676 127.587 93.065  1.00 59.07  ? 231 SER A C   1 
ATOM 1174 O O   . SER A 1 231 ? 119.680 128.360 94.032  1.00 61.95  ? 231 SER A O   1 
ATOM 1175 C CB  . SER A 1 231 ? 121.657 127.546 91.532  1.00 66.63  ? 231 SER A CB  1 
ATOM 1176 O OG  . SER A 1 231 ? 122.181 128.790 91.959  1.00 74.49  ? 231 SER A OG  1 
ATOM 1177 N N   . ALA A 1 232 ? 118.586 127.375 92.325  1.00 58.36  ? 232 ALA A N   1 
ATOM 1178 C CA  . ALA A 1 232 ? 117.320 128.011 92.666  1.00 60.06  ? 232 ALA A CA  1 
ATOM 1179 C C   . ALA A 1 232 ? 116.793 127.510 94.003  1.00 61.66  ? 232 ALA A C   1 
ATOM 1180 O O   . ALA A 1 232 ? 116.273 128.297 94.805  1.00 66.21  ? 232 ALA A O   1 
ATOM 1181 C CB  . ALA A 1 232 ? 116.296 127.768 91.557  1.00 60.74  ? 232 ALA A CB  1 
ATOM 1182 N N   . ALA A 1 233 ? 116.921 126.204 94.261  1.00 60.26  ? 233 ALA A N   1 
ATOM 1183 C CA  . ALA A 1 233 ? 116.501 125.657 95.546  1.00 60.85  ? 233 ALA A CA  1 
ATOM 1184 C C   . ALA A 1 233 ? 117.322 126.241 96.685  1.00 62.55  ? 233 ALA A C   1 
ATOM 1185 O O   . ALA A 1 233 ? 116.781 126.545 97.758  1.00 68.54  ? 233 ALA A O   1 
ATOM 1186 C CB  . ALA A 1 233 ? 116.611 124.133 95.530  1.00 59.54  ? 233 ALA A CB  1 
ATOM 1187 N N   . PHE A 1 234 ? 118.628 126.425 96.461  1.00 59.85  ? 234 PHE A N   1 
ATOM 1188 C CA  . PHE A 1 234 ? 119.465 127.071 97.465  1.00 62.33  ? 234 PHE A CA  1 
ATOM 1189 C C   . PHE A 1 234 ? 119.027 128.508 97.703  1.00 63.07  ? 234 PHE A C   1 
ATOM 1190 O O   . PHE A 1 234 ? 119.045 128.985 98.842  1.00 65.24  ? 234 PHE A O   1 
ATOM 1191 C CB  . PHE A 1 234 ? 120.935 127.035 97.050  1.00 63.95  ? 234 PHE A CB  1 
ATOM 1192 C CG  . PHE A 1 234 ? 121.770 128.092 97.714  1.00 64.31  ? 234 PHE A CG  1 
ATOM 1193 C CD1 . PHE A 1 234 ? 122.067 128.011 99.063  1.00 65.46  ? 234 PHE A CD1 1 
ATOM 1194 C CD2 . PHE A 1 234 ? 122.250 129.170 96.994  1.00 70.05  ? 234 PHE A CD2 1 
ATOM 1195 C CE1 . PHE A 1 234 ? 122.820 128.982 99.678  1.00 73.05  ? 234 PHE A CE1 1 
ATOM 1196 C CE2 . PHE A 1 234 ? 123.009 130.146 97.605  1.00 75.05  ? 234 PHE A CE2 1 
ATOM 1197 C CZ  . PHE A 1 234 ? 123.293 130.050 98.948  1.00 76.69  ? 234 PHE A CZ  1 
ATOM 1198 N N   . PHE A 1 235 ? 118.643 129.215 96.640  1.00 62.04  ? 235 PHE A N   1 
ATOM 1199 C CA  . PHE A 1 235 ? 118.215 130.601 96.804  1.00 62.55  ? 235 PHE A CA  1 
ATOM 1200 C C   . PHE A 1 235 ? 116.917 130.697 97.597  1.00 61.26  ? 235 PHE A C   1 
ATOM 1201 O O   . PHE A 1 235 ? 116.777 131.579 98.455  1.00 64.94  ? 235 PHE A O   1 
ATOM 1202 C CB  . PHE A 1 235 ? 118.079 131.276 95.442  1.00 64.69  ? 235 PHE A CB  1 
ATOM 1203 C CG  . PHE A 1 235 ? 119.332 131.970 94.991  1.00 68.74  ? 235 PHE A CG  1 
ATOM 1204 C CD1 . PHE A 1 235 ? 120.241 132.451 95.919  1.00 68.05  ? 235 PHE A CD1 1 
ATOM 1205 C CD2 . PHE A 1 235 ? 119.603 132.138 93.643  1.00 75.05  ? 235 PHE A CD2 1 
ATOM 1206 C CE1 . PHE A 1 235 ? 121.395 133.089 95.514  1.00 73.78  ? 235 PHE A CE1 1 
ATOM 1207 C CE2 . PHE A 1 235 ? 120.759 132.777 93.229  1.00 80.96  ? 235 PHE A CE2 1 
ATOM 1208 C CZ  . PHE A 1 235 ? 121.655 133.253 94.169  1.00 80.71  ? 235 PHE A CZ  1 
ATOM 1209 N N   . MET A 1 236 ? 115.967 129.791 97.344  1.00 60.81  ? 236 MET A N   1 
ATOM 1210 C CA  . MET A 1 236 ? 114.742 129.776 98.146  1.00 63.71  ? 236 MET A CA  1 
ATOM 1211 C C   . MET A 1 236 ? 115.021 129.420 99.602  1.00 57.73  ? 236 MET A C   1 
ATOM 1212 O O   . MET A 1 236 ? 114.420 130.008 100.513 1.00 57.86  ? 236 MET A O   1 
ATOM 1213 C CB  . MET A 1 236 ? 113.703 128.820 97.560  1.00 66.80  ? 236 MET A CB  1 
ATOM 1214 C CG  . MET A 1 236 ? 113.452 128.968 96.074  1.00 77.41  ? 236 MET A CG  1 
ATOM 1215 S SD  . MET A 1 236 ? 112.155 130.158 95.670  1.00 115.27 ? 236 MET A SD  1 
ATOM 1216 C CE  . MET A 1 236 ? 111.067 130.000 97.086  1.00 78.10  ? 236 MET A CE  1 
ATOM 1217 N N   . VAL A 1 237 ? 115.920 128.460 99.842  1.00 53.49  ? 237 VAL A N   1 
ATOM 1218 C CA  . VAL A 1 237 ? 116.255 128.079 101.213 1.00 53.15  ? 237 VAL A CA  1 
ATOM 1219 C C   . VAL A 1 237 ? 116.923 129.238 101.944 1.00 55.00  ? 237 VAL A C   1 
ATOM 1220 O O   . VAL A 1 237 ? 116.597 129.533 103.102 1.00 60.27  ? 237 VAL A O   1 
ATOM 1221 C CB  . VAL A 1 237 ? 117.133 126.813 101.214 1.00 54.09  ? 237 VAL A CB  1 
ATOM 1222 C CG1 . VAL A 1 237 ? 117.800 126.612 102.561 1.00 53.40  ? 237 VAL A CG1 1 
ATOM 1223 C CG2 . VAL A 1 237 ? 116.293 125.594 100.867 1.00 55.39  ? 237 VAL A CG2 1 
ATOM 1224 N N   . PHE A 1 238 ? 117.836 129.938 101.267 1.00 55.33  ? 238 PHE A N   1 
ATOM 1225 C CA  . PHE A 1 238 ? 118.500 131.092 101.864 1.00 58.28  ? 238 PHE A CA  1 
ATOM 1226 C C   . PHE A 1 238 ? 117.516 132.220 102.146 1.00 52.89  ? 238 PHE A C   1 
ATOM 1227 O O   . PHE A 1 238 ? 117.601 132.873 103.191 1.00 55.26  ? 238 PHE A O   1 
ATOM 1228 C CB  . PHE A 1 238 ? 119.622 131.574 100.951 1.00 66.93  ? 238 PHE A CB  1 
ATOM 1229 C CG  . PHE A 1 238 ? 120.341 132.784 101.462 1.00 69.62  ? 238 PHE A CG  1 
ATOM 1230 C CD1 . PHE A 1 238 ? 121.067 132.728 102.636 1.00 71.89  ? 238 PHE A CD1 1 
ATOM 1231 C CD2 . PHE A 1 238 ? 120.292 133.979 100.766 1.00 69.21  ? 238 PHE A CD2 1 
ATOM 1232 C CE1 . PHE A 1 238 ? 121.730 133.839 103.107 1.00 74.34  ? 238 PHE A CE1 1 
ATOM 1233 C CE2 . PHE A 1 238 ? 120.954 135.093 101.233 1.00 70.73  ? 238 PHE A CE2 1 
ATOM 1234 C CZ  . PHE A 1 238 ? 121.673 135.022 102.405 1.00 73.10  ? 238 PHE A CZ  1 
ATOM 1235 N N   . GLY A 1 239 ? 116.561 132.444 101.241 1.00 49.72  ? 239 GLY A N   1 
ATOM 1236 C CA  . GLY A 1 239 ? 115.561 133.473 101.476 1.00 48.19  ? 239 GLY A CA  1 
ATOM 1237 C C   . GLY A 1 239 ? 114.648 133.171 102.650 1.00 50.39  ? 239 GLY A C   1 
ATOM 1238 O O   . GLY A 1 239 ? 114.372 134.051 103.475 1.00 55.34  ? 239 GLY A O   1 
ATOM 1239 N N   . ILE A 1 240 ? 114.167 131.927 102.750 1.00 49.15  ? 240 ILE A N   1 
ATOM 1240 C CA  . ILE A 1 240 ? 113.276 131.605 103.861 1.00 44.65  ? 240 ILE A CA  1 
ATOM 1241 C C   . ILE A 1 240 ? 114.044 131.563 105.178 1.00 44.25  ? 240 ILE A C   1 
ATOM 1242 O O   . ILE A 1 240 ? 113.495 131.919 106.230 1.00 47.82  ? 240 ILE A O   1 
ATOM 1243 C CB  . ILE A 1 240 ? 112.486 130.306 103.601 1.00 44.91  ? 240 ILE A CB  1 
ATOM 1244 C CG1 . ILE A 1 240 ? 113.399 129.090 103.487 1.00 44.71  ? 240 ILE A CG1 1 
ATOM 1245 C CG2 . ILE A 1 240 ? 111.629 130.454 102.356 1.00 45.84  ? 240 ILE A CG2 1 
ATOM 1246 C CD1 . ILE A 1 240 ? 112.676 127.817 103.093 1.00 49.00  ? 240 ILE A CD1 1 
ATOM 1247 N N   . MET A 1 241 ? 115.324 131.181 105.148 1.00 44.52  ? 241 MET A N   1 
ATOM 1248 C CA  . MET A 1 241 ? 116.142 131.247 106.354 1.00 47.55  ? 241 MET A CA  1 
ATOM 1249 C C   . MET A 1 241 ? 116.373 132.690 106.778 1.00 49.27  ? 241 MET A C   1 
ATOM 1250 O O   . MET A 1 241 ? 116.353 133.003 107.977 1.00 54.13  ? 241 MET A O   1 
ATOM 1251 C CB  . MET A 1 241 ? 117.469 130.526 106.124 1.00 49.70  ? 241 MET A CB  1 
ATOM 1252 C CG  . MET A 1 241 ? 118.422 130.560 107.301 1.00 52.51  ? 241 MET A CG  1 
ATOM 1253 S SD  . MET A 1 241 ? 119.497 129.114 107.427 1.00 86.57  ? 241 MET A SD  1 
ATOM 1254 C CE  . MET A 1 241 ? 119.412 128.434 105.770 1.00 69.56  ? 241 MET A CE  1 
ATOM 1255 N N   . LEU A 1 242 ? 116.558 133.587 105.804 1.00 48.49  ? 242 LEU A N   1 
ATOM 1256 C CA  . LEU A 1 242 ? 116.689 135.009 106.100 1.00 45.18  ? 242 LEU A CA  1 
ATOM 1257 C C   . LEU A 1 242 ? 115.433 135.554 106.764 1.00 45.09  ? 242 LEU A C   1 
ATOM 1258 O O   . LEU A 1 242 ? 115.511 136.229 107.798 1.00 50.18  ? 242 LEU A O   1 
ATOM 1259 C CB  . LEU A 1 242 ? 116.991 135.779 104.816 1.00 44.16  ? 242 LEU A CB  1 
ATOM 1260 C CG  . LEU A 1 242 ? 117.317 137.266 104.941 1.00 47.73  ? 242 LEU A CG  1 
ATOM 1261 C CD1 . LEU A 1 242 ? 118.394 137.498 105.983 1.00 53.13  ? 242 LEU A CD1 1 
ATOM 1262 C CD2 . LEU A 1 242 ? 117.748 137.828 103.593 1.00 54.17  ? 242 LEU A CD2 1 
ATOM 1263 N N   . HIS A 1 243 ? 114.263 135.239 106.201 1.00 41.26  ? 243 HIS A N   1 
ATOM 1264 C CA  . HIS A 1 243 ? 113.015 135.747 106.768 1.00 43.26  ? 243 HIS A CA  1 
ATOM 1265 C C   . HIS A 1 243 ? 112.758 135.182 108.159 1.00 49.29  ? 243 HIS A C   1 
ATOM 1266 O O   . HIS A 1 243 ? 112.326 135.914 109.064 1.00 53.60  ? 243 HIS A O   1 
ATOM 1267 C CB  . HIS A 1 243 ? 111.842 135.429 105.851 1.00 41.70  ? 243 HIS A CB  1 
ATOM 1268 C CG  . HIS A 1 243 ? 110.508 135.634 106.495 1.00 48.42  ? 243 HIS A CG  1 
ATOM 1269 N ND1 . HIS A 1 243 ? 109.804 134.610 107.087 1.00 52.62  ? 243 HIS A ND1 1 
ATOM 1270 C CD2 . HIS A 1 243 ? 109.752 136.748 106.646 1.00 57.54  ? 243 HIS A CD2 1 
ATOM 1271 C CE1 . HIS A 1 243 ? 108.671 135.082 107.573 1.00 63.65  ? 243 HIS A CE1 1 
ATOM 1272 N NE2 . HIS A 1 243 ? 108.614 136.377 107.318 1.00 66.84  ? 243 HIS A NE2 1 
ATOM 1273 N N   . LEU A 1 244 ? 113.040 133.892 108.355 1.00 49.19  ? 244 LEU A N   1 
ATOM 1274 C CA  . LEU A 1 244 ? 112.865 133.286 109.669 1.00 46.63  ? 244 LEU A CA  1 
ATOM 1275 C C   . LEU A 1 244 ? 113.824 133.887 110.687 1.00 47.39  ? 244 LEU A C   1 
ATOM 1276 O O   . LEU A 1 244 ? 113.480 134.023 111.867 1.00 50.91  ? 244 LEU A O   1 
ATOM 1277 C CB  . LEU A 1 244 ? 113.049 131.775 109.574 1.00 43.84  ? 244 LEU A CB  1 
ATOM 1278 C CG  . LEU A 1 244 ? 111.768 130.942 109.557 1.00 45.99  ? 244 LEU A CG  1 
ATOM 1279 C CD1 . LEU A 1 244 ? 110.826 131.388 108.454 1.00 48.14  ? 244 LEU A CD1 1 
ATOM 1280 C CD2 . LEU A 1 244 ? 112.097 129.471 109.400 1.00 45.14  ? 244 LEU A CD2 1 
ATOM 1281 N N   . TYR A 1 245 ? 115.017 134.289 110.248 1.00 43.94  ? 245 TYR A N   1 
ATOM 1282 C CA  . TYR A 1 245 ? 115.938 134.906 111.189 1.00 44.15  ? 245 TYR A CA  1 
ATOM 1283 C C   . TYR A 1 245 ? 115.533 136.329 111.545 1.00 46.80  ? 245 TYR A C   1 
ATOM 1284 O O   . TYR A 1 245 ? 115.751 136.751 112.686 1.00 54.65  ? 245 TYR A O   1 
ATOM 1285 C CB  . TYR A 1 245 ? 117.358 134.859 110.651 1.00 47.70  ? 245 TYR A CB  1 
ATOM 1286 C CG  . TYR A 1 245 ? 118.121 133.700 111.225 1.00 56.57  ? 245 TYR A CG  1 
ATOM 1287 C CD1 . TYR A 1 245 ? 118.463 133.676 112.567 1.00 57.16  ? 245 TYR A CD1 1 
ATOM 1288 C CD2 . TYR A 1 245 ? 118.472 132.617 110.439 1.00 65.53  ? 245 TYR A CD2 1 
ATOM 1289 C CE1 . TYR A 1 245 ? 119.147 132.616 113.107 1.00 68.05  ? 245 TYR A CE1 1 
ATOM 1290 C CE2 . TYR A 1 245 ? 119.160 131.551 110.970 1.00 68.82  ? 245 TYR A CE2 1 
ATOM 1291 C CZ  . TYR A 1 245 ? 119.493 131.556 112.305 1.00 71.34  ? 245 TYR A CZ  1 
ATOM 1292 O OH  . TYR A 1 245 ? 120.180 130.493 112.842 1.00 71.46  ? 245 TYR A OH  1 
ATOM 1293 N N   . VAL A 1 246 ? 114.933 137.079 110.614 1.00 40.75  ? 246 VAL A N   1 
ATOM 1294 C CA  . VAL A 1 246 ? 114.381 138.379 111.011 1.00 45.96  ? 246 VAL A CA  1 
ATOM 1295 C C   . VAL A 1 246 ? 113.221 138.199 111.984 1.00 50.19  ? 246 VAL A C   1 
ATOM 1296 O O   . VAL A 1 246 ? 113.076 138.976 112.936 1.00 56.07  ? 246 VAL A O   1 
ATOM 1297 C CB  . VAL A 1 246 ? 113.977 139.244 109.801 1.00 46.88  ? 246 VAL A CB  1 
ATOM 1298 C CG1 . VAL A 1 246 ? 113.917 140.700 110.213 1.00 49.58  ? 246 VAL A CG1 1 
ATOM 1299 C CG2 . VAL A 1 246 ? 115.010 139.172 108.728 1.00 46.66  ? 246 VAL A CG2 1 
ATOM 1300 N N   . ARG A 1 247 ? 112.387 137.174 111.780 1.00 48.83  ? 247 ARG A N   1 
ATOM 1301 C CA  . ARG A 1 247 ? 111.303 136.939 112.736 1.00 49.22  ? 247 ARG A CA  1 
ATOM 1302 C C   . ARG A 1 247 ? 111.821 136.501 114.104 1.00 48.33  ? 247 ARG A C   1 
ATOM 1303 O O   . ARG A 1 247 ? 111.203 136.821 115.125 1.00 52.75  ? 247 ARG A O   1 
ATOM 1304 C CB  . ARG A 1 247 ? 110.312 135.910 112.197 1.00 54.26  ? 247 ARG A CB  1 
ATOM 1305 C CG  . ARG A 1 247 ? 109.659 136.304 110.889 1.00 54.00  ? 247 ARG A CG  1 
ATOM 1306 C CD  . ARG A 1 247 ? 109.000 137.663 110.985 1.00 55.05  ? 247 ARG A CD  1 
ATOM 1307 N NE  . ARG A 1 247 ? 108.002 137.721 112.045 1.00 60.34  ? 247 ARG A NE  1 
ATOM 1308 C CZ  . ARG A 1 247 ? 106.752 137.292 111.925 1.00 67.95  ? 247 ARG A CZ  1 
ATOM 1309 N NH1 . ARG A 1 247 ? 106.307 136.757 110.799 1.00 69.23  ? 247 ARG A NH1 1 
ATOM 1310 N NH2 . ARG A 1 247 ? 105.922 137.417 112.957 1.00 68.73  ? 247 ARG A NH2 1 
ATOM 1311 N N   . ILE A 1 248 ? 112.930 135.762 114.148 1.00 46.39  ? 248 ILE A N   1 
ATOM 1312 C CA  . ILE A 1 248 ? 113.542 135.396 115.426 1.00 45.75  ? 248 ILE A CA  1 
ATOM 1313 C C   . ILE A 1 248 ? 114.116 136.630 116.119 1.00 50.17  ? 248 ILE A C   1 
ATOM 1314 O O   . ILE A 1 248 ? 113.908 136.862 117.321 1.00 58.24  ? 248 ILE A O   1 
ATOM 1315 C CB  . ILE A 1 248 ? 114.619 134.319 115.202 1.00 47.16  ? 248 ILE A CB  1 
ATOM 1316 C CG1 . ILE A 1 248 ? 113.973 132.958 114.962 1.00 47.70  ? 248 ILE A CG1 1 
ATOM 1317 C CG2 . ILE A 1 248 ? 115.598 134.253 116.362 1.00 47.24  ? 248 ILE A CG2 1 
ATOM 1318 C CD1 . ILE A 1 248 ? 114.967 131.854 114.703 1.00 47.94  ? 248 ILE A CD1 1 
ATOM 1319 N N   . CYS A 1 249 ? 114.837 137.454 115.369 1.00 48.36  ? 249 CYS A N   1 
ATOM 1320 C CA  . CYS A 1 249 ? 115.505 138.581 115.995 1.00 52.62  ? 249 CYS A CA  1 
ATOM 1321 C C   . CYS A 1 249 ? 114.547 139.716 116.315 1.00 55.94  ? 249 CYS A C   1 
ATOM 1322 O O   . CYS A 1 249 ? 114.892 140.582 117.127 1.00 61.03  ? 249 CYS A O   1 
ATOM 1323 C CB  . CYS A 1 249 ? 116.648 139.036 115.107 1.00 51.54  ? 249 CYS A CB  1 
ATOM 1324 S SG  . CYS A 1 249 ? 117.850 137.714 115.003 1.00 65.63  ? 249 CYS A SG  1 
ATOM 1325 N N   . GLN A 1 250 ? 113.339 139.693 115.743 1.00 52.93  ? 250 GLN A N   1 
ATOM 1326 C CA  . GLN A 1 250 ? 112.303 140.641 116.134 1.00 49.74  ? 250 GLN A CA  1 
ATOM 1327 C C   . GLN A 1 250 ? 111.923 140.496 117.600 1.00 51.27  ? 250 GLN A C   1 
ATOM 1328 O O   . GLN A 1 250 ? 111.534 141.482 118.236 1.00 60.48  ? 250 GLN A O   1 
ATOM 1329 C CB  . GLN A 1 250 ? 111.071 140.455 115.253 1.00 55.61  ? 250 GLN A CB  1 
ATOM 1330 C CG  . GLN A 1 250 ? 110.664 141.689 114.485 1.00 63.20  ? 250 GLN A CG  1 
ATOM 1331 C CD  . GLN A 1 250 ? 109.430 141.461 113.642 1.00 70.75  ? 250 GLN A CD  1 
ATOM 1332 O OE1 . GLN A 1 250 ? 109.464 140.720 112.659 1.00 70.14  ? 250 GLN A OE1 1 
ATOM 1333 N NE2 . GLN A 1 250 ? 108.328 142.097 114.021 1.00 71.13  ? 250 GLN A NE2 1 
ATOM 1334 N N   . VAL A 1 251 ? 112.022 139.290 118.157 1.00 48.34  ? 251 VAL A N   1 
ATOM 1335 C CA  . VAL A 1 251 ? 111.783 139.115 119.583 1.00 54.13  ? 251 VAL A CA  1 
ATOM 1336 C C   . VAL A 1 251 ? 113.076 139.028 120.384 1.00 55.95  ? 251 VAL A C   1 
ATOM 1337 O O   . VAL A 1 251 ? 113.050 139.292 121.598 1.00 62.30  ? 251 VAL A O   1 
ATOM 1338 C CB  . VAL A 1 251 ? 110.886 137.892 119.869 1.00 56.32  ? 251 VAL A CB  1 
ATOM 1339 C CG1 . VAL A 1 251 ? 109.609 137.982 119.057 1.00 58.96  ? 251 VAL A CG1 1 
ATOM 1340 C CG2 . VAL A 1 251 ? 111.613 136.597 119.600 1.00 51.36  ? 251 VAL A CG2 1 
ATOM 1341 N N   . VAL A 1 252 ? 114.204 138.704 119.743 1.00 50.49  ? 252 VAL A N   1 
ATOM 1342 C CA  . VAL A 1 252 ? 115.496 138.827 120.424 1.00 52.51  ? 252 VAL A CA  1 
ATOM 1343 C C   . VAL A 1 252 ? 115.745 140.276 120.833 1.00 53.69  ? 252 VAL A C   1 
ATOM 1344 O O   . VAL A 1 252 ? 116.130 140.564 121.976 1.00 57.55  ? 252 VAL A O   1 
ATOM 1345 C CB  . VAL A 1 252 ? 116.629 138.294 119.530 1.00 54.00  ? 252 VAL A CB  1 
ATOM 1346 C CG1 . VAL A 1 252 ? 117.986 138.652 120.106 1.00 56.05  ? 252 VAL A CG1 1 
ATOM 1347 C CG2 . VAL A 1 252 ? 116.507 136.797 119.354 1.00 57.41  ? 252 VAL A CG2 1 
ATOM 1348 N N   . TRP A 1 253 ? 115.489 141.210 119.913 1.00 55.66  ? 253 TRP A N   1 
ATOM 1349 C CA  . TRP A 1 253 ? 115.667 142.630 120.200 1.00 60.68  ? 253 TRP A CA  1 
ATOM 1350 C C   . TRP A 1 253 ? 114.693 143.112 121.267 1.00 62.67  ? 253 TRP A C   1 
ATOM 1351 O O   . TRP A 1 253 ? 115.052 143.942 122.109 1.00 68.30  ? 253 TRP A O   1 
ATOM 1352 C CB  . TRP A 1 253 ? 115.499 143.438 118.916 1.00 67.75  ? 253 TRP A CB  1 
ATOM 1353 C CG  . TRP A 1 253 ? 115.749 144.896 119.078 1.00 82.68  ? 253 TRP A CG  1 
ATOM 1354 C CD1 . TRP A 1 253 ? 114.814 145.888 119.108 1.00 87.63  ? 253 TRP A CD1 1 
ATOM 1355 C CD2 . TRP A 1 253 ? 117.020 145.538 119.222 1.00 90.76  ? 253 TRP A CD2 1 
ATOM 1356 N NE1 . TRP A 1 253 ? 115.424 147.109 119.268 1.00 92.48  ? 253 TRP A NE1 1 
ATOM 1357 C CE2 . TRP A 1 253 ? 116.778 146.921 119.340 1.00 95.76  ? 253 TRP A CE2 1 
ATOM 1358 C CE3 . TRP A 1 253 ? 118.339 145.077 119.266 1.00 88.67  ? 253 TRP A CE3 1 
ATOM 1359 C CZ2 . TRP A 1 253 ? 117.806 147.848 119.499 1.00 100.93 ? 253 TRP A CZ2 1 
ATOM 1360 C CZ3 . TRP A 1 253 ? 119.359 145.999 119.424 1.00 95.71  ? 253 TRP A CZ3 1 
ATOM 1361 C CH2 . TRP A 1 253 ? 119.087 147.368 119.538 1.00 100.63 ? 253 TRP A CH2 1 
ATOM 1362 N N   . ARG A 1 254 ? 113.459 142.601 121.249 1.00 58.96  ? 254 ARG A N   1 
ATOM 1363 C CA  . ARG A 1 254 ? 112.469 142.988 122.251 1.00 61.68  ? 254 ARG A CA  1 
ATOM 1364 C C   . ARG A 1 254 ? 112.868 142.521 123.643 1.00 61.93  ? 254 ARG A C   1 
ATOM 1365 O O   . ARG A 1 254 ? 112.748 143.279 124.617 1.00 66.48  ? 254 ARG A O   1 
ATOM 1366 C CB  . ARG A 1 254 ? 111.103 142.423 121.874 1.00 59.29  ? 254 ARG A CB  1 
ATOM 1367 C CG  . ARG A 1 254 ? 109.939 143.182 122.460 1.00 63.24  ? 254 ARG A CG  1 
ATOM 1368 C CD  . ARG A 1 254 ? 108.695 142.323 122.490 1.00 66.37  ? 254 ARG A CD  1 
ATOM 1369 N NE  . ARG A 1 254 ? 108.944 141.025 123.102 1.00 71.02  ? 254 ARG A NE  1 
ATOM 1370 C CZ  . ARG A 1 254 ? 107.996 140.154 123.416 1.00 74.66  ? 254 ARG A CZ  1 
ATOM 1371 N NH1 . ARG A 1 254 ? 106.719 140.413 123.191 1.00 76.39  ? 254 ARG A NH1 1 
ATOM 1372 N NH2 . ARG A 1 254 ? 108.337 138.995 123.969 1.00 72.24  ? 254 ARG A NH2 1 
ATOM 1373 N N   . HIS A 1 255 ? 113.347 141.280 123.757 1.00 59.07  ? 255 HIS A N   1 
ATOM 1374 C CA  . HIS A 1 255 ? 113.802 140.780 125.049 1.00 60.13  ? 255 HIS A CA  1 
ATOM 1375 C C   . HIS A 1 255 ? 115.021 141.544 125.544 1.00 63.81  ? 255 HIS A C   1 
ATOM 1376 O O   . HIS A 1 255 ? 115.124 141.846 126.740 1.00 67.53  ? 255 HIS A O   1 
ATOM 1377 C CB  . HIS A 1 255 ? 114.104 139.288 124.954 1.00 59.06  ? 255 HIS A CB  1 
ATOM 1378 C CG  . HIS A 1 255 ? 112.887 138.426 125.037 1.00 59.54  ? 255 HIS A CG  1 
ATOM 1379 N ND1 . HIS A 1 255 ? 111.755 138.806 125.721 1.00 58.97  ? 255 HIS A ND1 1 
ATOM 1380 C CD2 . HIS A 1 255 ? 112.620 137.206 124.516 1.00 60.90  ? 255 HIS A CD2 1 
ATOM 1381 C CE1 . HIS A 1 255 ? 110.843 137.857 125.622 1.00 60.88  ? 255 HIS A CE1 1 
ATOM 1382 N NE2 . HIS A 1 255 ? 111.342 136.875 124.895 1.00 63.93  ? 255 HIS A NE2 1 
ATOM 1383 N N   . ALA A 1 256 ? 115.948 141.877 124.640 1.00 64.11  ? 256 ALA A N   1 
ATOM 1384 C CA  . ALA A 1 256 ? 117.117 142.658 125.034 1.00 62.90  ? 256 ALA A CA  1 
ATOM 1385 C C   . ALA A 1 256 ? 116.723 144.055 125.496 1.00 62.73  ? 256 ALA A C   1 
ATOM 1386 O O   . ALA A 1 256 ? 117.287 144.580 126.464 1.00 64.98  ? 256 ALA A O   1 
ATOM 1387 C CB  . ALA A 1 256 ? 118.112 142.735 123.877 1.00 64.67  ? 256 ALA A CB  1 
ATOM 1388 N N   . HIS A 1 257 ? 115.748 144.669 124.821 1.00 64.41  ? 257 HIS A N   1 
ATOM 1389 C CA  . HIS A 1 257 ? 115.294 145.998 125.213 1.00 69.21  ? 257 HIS A CA  1 
ATOM 1390 C C   . HIS A 1 257 ? 114.604 145.973 126.569 1.00 71.96  ? 257 HIS A C   1 
ATOM 1391 O O   . HIS A 1 257 ? 114.816 146.870 127.391 1.00 76.02  ? 257 HIS A O   1 
ATOM 1392 C CB  . HIS A 1 257 ? 114.364 146.569 124.146 1.00 72.75  ? 257 HIS A CB  1 
ATOM 1393 C CG  . HIS A 1 257 ? 113.240 147.387 124.700 1.00 82.46  ? 257 HIS A CG  1 
ATOM 1394 N ND1 . HIS A 1 257 ? 113.425 148.649 125.222 1.00 87.68  ? 257 HIS A ND1 1 
ATOM 1395 C CD2 . HIS A 1 257 ? 111.917 147.123 124.814 1.00 84.92  ? 257 HIS A CD2 1 
ATOM 1396 C CE1 . HIS A 1 257 ? 112.264 149.127 125.634 1.00 88.97  ? 257 HIS A CE1 1 
ATOM 1397 N NE2 . HIS A 1 257 ? 111.333 148.221 125.397 1.00 92.20  ? 257 HIS A NE2 1 
ATOM 1398 N N   . GLN A 1 258 ? 113.779 144.952 126.824 1.00 71.47  ? 258 GLN A N   1 
ATOM 1399 C CA  . GLN A 1 258 ? 113.134 144.832 128.130 1.00 72.38  ? 258 GLN A CA  1 
ATOM 1400 C C   . GLN A 1 258 ? 114.154 144.575 129.234 1.00 71.95  ? 258 GLN A C   1 
ATOM 1401 O O   . GLN A 1 258 ? 114.026 145.114 130.342 1.00 75.30  ? 258 GLN A O   1 
ATOM 1402 C CB  . GLN A 1 258 ? 112.088 143.721 128.100 1.00 71.31  ? 258 GLN A CB  1 
ATOM 1403 C CG  . GLN A 1 258 ? 110.666 144.215 127.932 1.00 77.40  ? 258 GLN A CG  1 
ATOM 1404 C CD  . GLN A 1 258 ? 110.354 145.403 128.816 1.00 83.13  ? 258 GLN A CD  1 
ATOM 1405 O OE1 . GLN A 1 258 ? 110.117 146.508 128.330 1.00 83.30  ? 258 GLN A OE1 1 
ATOM 1406 N NE2 . GLN A 1 258 ? 110.347 145.180 130.125 1.00 85.58  ? 258 GLN A NE2 1 
ATOM 1407 N N   . ILE A 1 259 ? 115.175 143.765 128.944 1.00 70.40  ? 259 ILE A N   1 
ATOM 1408 C CA  . ILE A 1 259 ? 116.222 143.474 129.918 1.00 67.56  ? 259 ILE A CA  1 
ATOM 1409 C C   . ILE A 1 259 ? 117.016 144.736 130.246 1.00 70.44  ? 259 ILE A C   1 
ATOM 1410 O O   . ILE A 1 259 ? 117.306 145.018 131.415 1.00 71.54  ? 259 ILE A O   1 
ATOM 1411 C CB  . ILE A 1 259 ? 117.116 142.346 129.374 1.00 68.07  ? 259 ILE A CB  1 
ATOM 1412 C CG1 . ILE A 1 259 ? 116.511 140.987 129.718 1.00 68.19  ? 259 ILE A CG1 1 
ATOM 1413 C CG2 . ILE A 1 259 ? 118.540 142.443 129.921 1.00 67.93  ? 259 ILE A CG2 1 
ATOM 1414 C CD1 . ILE A 1 259 ? 117.419 139.819 129.425 1.00 66.72  ? 259 ILE A CD1 1 
ATOM 1415 N N   . ALA A 1 260 ? 117.358 145.526 129.225 1.00 72.60  ? 260 ALA A N   1 
ATOM 1416 C CA  . ALA A 1 260 ? 118.093 146.765 129.457 1.00 72.85  ? 260 ALA A CA  1 
ATOM 1417 C C   . ALA A 1 260 ? 117.236 147.811 130.157 1.00 75.03  ? 260 ALA A C   1 
ATOM 1418 O O   . ALA A 1 260 ? 117.754 148.594 130.959 1.00 80.37  ? 260 ALA A O   1 
ATOM 1419 C CB  . ALA A 1 260 ? 118.627 147.316 128.136 1.00 72.40  ? 260 ALA A CB  1 
ATOM 1420 N N   . LEU A 1 261 ? 115.935 147.851 129.864 1.00 75.11  ? 261 LEU A N   1 
ATOM 1421 C CA  . LEU A 1 261 ? 115.039 148.777 130.543 1.00 75.80  ? 261 LEU A CA  1 
ATOM 1422 C C   . LEU A 1 261 ? 114.789 148.366 131.988 1.00 78.10  ? 261 LEU A C   1 
ATOM 1423 O O   . LEU A 1 261 ? 114.438 149.218 132.811 1.00 81.53  ? 261 LEU A O   1 
ATOM 1424 C CB  . LEU A 1 261 ? 113.728 148.874 129.753 1.00 81.43  ? 261 LEU A CB  1 
ATOM 1425 C CG  . LEU A 1 261 ? 112.454 149.543 130.278 1.00 87.00  ? 261 LEU A CG  1 
ATOM 1426 C CD1 . LEU A 1 261 ? 111.803 150.352 129.170 1.00 89.59  ? 261 LEU A CD1 1 
ATOM 1427 C CD2 . LEU A 1 261 ? 111.476 148.512 130.822 1.00 84.50  ? 261 LEU A CD2 1 
ATOM 1428 N N   . GLN A 1 262 ? 114.975 147.083 132.311 1.00 79.30  ? 262 GLN A N   1 
ATOM 1429 C CA  . GLN A 1 262 ? 114.797 146.618 133.684 1.00 80.76  ? 262 GLN A CA  1 
ATOM 1430 C C   . GLN A 1 262 ? 115.835 147.221 134.624 1.00 80.89  ? 262 GLN A C   1 
ATOM 1431 O O   . GLN A 1 262 ? 115.515 147.568 135.766 1.00 84.17  ? 262 GLN A O   1 
ATOM 1432 C CB  . GLN A 1 262 ? 114.855 145.092 133.724 1.00 82.40  ? 262 GLN A CB  1 
ATOM 1433 C CG  . GLN A 1 262 ? 114.046 144.464 134.840 1.00 84.07  ? 262 GLN A CG  1 
ATOM 1434 C CD  . GLN A 1 262 ? 114.757 143.289 135.476 1.00 88.17  ? 262 GLN A CD  1 
ATOM 1435 O OE1 . GLN A 1 262 ? 115.949 143.356 135.771 1.00 88.82  ? 262 GLN A OE1 1 
ATOM 1436 N NE2 . GLN A 1 262 ? 114.028 142.201 135.687 1.00 86.02  ? 262 GLN A NE2 1 
ATOM 1437 N N   . GLN A 1 263 ? 117.078 147.352 134.170 1.00 83.36  ? 263 GLN A N   1 
ATOM 1438 C CA  . GLN A 1 263 ? 118.150 147.922 134.977 1.00 86.90  ? 263 GLN A CA  1 
ATOM 1439 C C   . GLN A 1 263 ? 118.342 149.384 134.594 1.00 93.94  ? 263 GLN A C   1 
ATOM 1440 O O   . GLN A 1 263 ? 118.657 149.691 133.441 1.00 92.17  ? 263 GLN A O   1 
ATOM 1441 C CB  . GLN A 1 263 ? 119.453 147.149 134.784 1.00 82.25  ? 263 GLN A CB  1 
ATOM 1442 C CG  . GLN A 1 263 ? 119.269 145.666 134.550 1.00 83.10  ? 263 GLN A CG  1 
ATOM 1443 C CD  . GLN A 1 263 ? 120.494 145.019 133.941 1.00 83.90  ? 263 GLN A CD  1 
ATOM 1444 O OE1 . GLN A 1 263 ? 121.249 145.658 133.211 1.00 84.03  ? 263 GLN A OE1 1 
ATOM 1445 N NE2 . GLN A 1 263 ? 120.699 143.742 134.239 1.00 83.30  ? 263 GLN A NE2 1 
ATOM 1446 N N   . HIS A 1 264 ? 118.172 150.276 135.563 1.00 103.00 ? 264 HIS A N   1 
ATOM 1447 C CA  . HIS A 1 264 ? 118.325 151.704 135.318 1.00 109.13 ? 264 HIS A CA  1 
ATOM 1448 C C   . HIS A 1 264 ? 119.792 152.082 135.139 1.00 108.94 ? 264 HIS A C   1 
ATOM 1449 O O   . HIS A 1 264 ? 120.688 151.292 135.436 1.00 107.22 ? 264 HIS A O   1 
ATOM 1450 C CB  . HIS A 1 264 ? 117.711 152.513 136.462 1.00 112.26 ? 264 HIS A CB  1 
ATOM 1451 C CG  . HIS A 1 264 ? 116.526 151.856 137.098 1.00 115.94 ? 264 HIS A CG  1 
ATOM 1452 N ND1 . HIS A 1 264 ? 115.241 152.023 136.627 1.00 115.68 ? 264 HIS A ND1 1 
ATOM 1453 C CD2 . HIS A 1 264 ? 116.429 151.035 138.171 1.00 118.68 ? 264 HIS A CD2 1 
ATOM 1454 C CE1 . HIS A 1 264 ? 114.405 151.331 137.380 1.00 118.58 ? 264 HIS A CE1 1 
ATOM 1455 N NE2 . HIS A 1 264 ? 115.101 150.723 138.324 1.00 122.01 ? 264 HIS A NE2 1 
ATOM 1456 N N   . THR A 1 274 ? 121.939 143.012 123.793 1.00 123.35 ? 274 THR A N   1 
ATOM 1457 C CA  . THR A 1 274 ? 123.350 143.377 123.830 1.00 128.08 ? 274 THR A CA  1 
ATOM 1458 C C   . THR A 1 274 ? 124.034 143.054 122.505 1.00 124.29 ? 274 THR A C   1 
ATOM 1459 O O   . THR A 1 274 ? 123.371 142.825 121.493 1.00 121.62 ? 274 THR A O   1 
ATOM 1460 C CB  . THR A 1 274 ? 124.092 142.655 124.970 1.00 127.65 ? 274 THR A CB  1 
ATOM 1461 O OG1 . THR A 1 274 ? 124.170 141.254 124.682 1.00 128.44 ? 274 THR A OG1 1 
ATOM 1462 C CG2 . THR A 1 274 ? 123.365 142.856 126.290 1.00 122.74 ? 274 THR A CG2 1 
ATOM 1463 N N   . ARG A 1 275 ? 125.366 143.038 122.520 1.00 122.75 ? 275 ARG A N   1 
ATOM 1464 C CA  . ARG A 1 275 ? 126.137 142.724 121.325 1.00 119.37 ? 275 ARG A CA  1 
ATOM 1465 C C   . ARG A 1 275 ? 126.238 141.229 121.059 1.00 111.28 ? 275 ARG A C   1 
ATOM 1466 O O   . ARG A 1 275 ? 126.651 140.840 119.957 1.00 109.62 ? 275 ARG A O   1 
ATOM 1467 C CB  . ARG A 1 275 ? 127.540 143.327 121.431 1.00 120.60 ? 275 ARG A CB  1 
ATOM 1468 C CG  . ARG A 1 275 ? 127.554 144.846 121.532 1.00 125.41 ? 275 ARG A CG  1 
ATOM 1469 C CD  . ARG A 1 275 ? 127.380 145.499 120.168 1.00 128.14 ? 275 ARG A CD  1 
ATOM 1470 N NE  . ARG A 1 275 ? 125.983 145.798 119.873 1.00 131.56 ? 275 ARG A NE  1 
ATOM 1471 C CZ  . ARG A 1 275 ? 125.456 147.014 119.889 1.00 131.98 ? 275 ARG A CZ  1 
ATOM 1472 N NH1 . ARG A 1 275 ? 126.184 148.079 120.182 1.00 133.78 ? 275 ARG A NH1 1 
ATOM 1473 N NH2 . ARG A 1 275 ? 124.166 147.167 119.603 1.00 132.30 ? 275 ARG A NH2 1 
ATOM 1474 N N   . LYS A 1 276 ? 125.867 140.395 122.035 1.00 107.82 ? 276 LYS A N   1 
ATOM 1475 C CA  . LYS A 1 276 ? 125.901 138.949 121.842 1.00 105.96 ? 276 LYS A CA  1 
ATOM 1476 C C   . LYS A 1 276 ? 124.934 138.513 120.751 1.00 107.18 ? 276 LYS A C   1 
ATOM 1477 O O   . LYS A 1 276 ? 125.266 137.651 119.932 1.00 103.23 ? 276 LYS A O   1 
ATOM 1478 C CB  . LYS A 1 276 ? 125.577 138.236 123.154 1.00 104.89 ? 276 LYS A CB  1 
ATOM 1479 C CG  . LYS A 1 276 ? 126.586 138.476 124.262 1.00 106.32 ? 276 LYS A CG  1 
ATOM 1480 C CD  . LYS A 1 276 ? 126.190 137.753 125.541 1.00 108.76 ? 276 LYS A CD  1 
ATOM 1481 C CE  . LYS A 1 276 ? 125.976 136.267 125.298 1.00 109.18 ? 276 LYS A CE  1 
ATOM 1482 N NZ  . LYS A 1 276 ? 125.415 135.583 126.496 1.00 113.70 ? 276 LYS A NZ  1 
ATOM 1483 N N   . GLY A 1 277 ? 123.741 139.112 120.716 1.00 108.07 ? 277 GLY A N   1 
ATOM 1484 C CA  . GLY A 1 277 ? 122.749 138.718 119.726 1.00 101.43 ? 277 GLY A CA  1 
ATOM 1485 C C   . GLY A 1 277 ? 123.155 139.057 118.304 1.00 99.23  ? 277 GLY A C   1 
ATOM 1486 O O   . GLY A 1 277 ? 123.031 138.227 117.399 1.00 97.85  ? 277 GLY A O   1 
ATOM 1487 N N   . VAL A 1 278 ? 123.661 140.274 118.087 1.00 101.04 ? 278 VAL A N   1 
ATOM 1488 C CA  . VAL A 1 278 ? 124.060 140.678 116.741 1.00 97.11  ? 278 VAL A CA  1 
ATOM 1489 C C   . VAL A 1 278 ? 125.322 139.934 116.313 1.00 91.87  ? 278 VAL A C   1 
ATOM 1490 O O   . VAL A 1 278 ? 125.457 139.534 115.147 1.00 91.57  ? 278 VAL A O   1 
ATOM 1491 C CB  . VAL A 1 278 ? 124.214 142.213 116.662 1.00 102.22 ? 278 VAL A CB  1 
ATOM 1492 C CG1 . VAL A 1 278 ? 125.003 142.751 117.833 1.00 106.32 ? 278 VAL A CG1 1 
ATOM 1493 C CG2 . VAL A 1 278 ? 124.827 142.658 115.335 1.00 100.63 ? 278 VAL A CG2 1 
ATOM 1494 N N   . GLY A 1 279 ? 126.247 139.700 117.250 1.00 93.20  ? 279 GLY A N   1 
ATOM 1495 C CA  . GLY A 1 279 ? 127.416 138.896 116.931 1.00 92.76  ? 279 GLY A CA  1 
ATOM 1496 C C   . GLY A 1 279 ? 127.062 137.469 116.559 1.00 90.05  ? 279 GLY A C   1 
ATOM 1497 O O   . GLY A 1 279 ? 127.599 136.918 115.590 1.00 92.03  ? 279 GLY A O   1 
ATOM 1498 N N   . THR A 1 280 ? 126.134 136.862 117.305 1.00 89.07  ? 280 THR A N   1 
ATOM 1499 C CA  . THR A 1 280 ? 125.688 135.510 116.997 1.00 89.26  ? 280 THR A CA  1 
ATOM 1500 C C   . THR A 1 280 ? 124.974 135.458 115.655 1.00 87.22  ? 280 THR A C   1 
ATOM 1501 O O   . THR A 1 280 ? 125.220 134.540 114.866 1.00 87.54  ? 280 THR A O   1 
ATOM 1502 C CB  . THR A 1 280 ? 124.784 134.988 118.112 1.00 92.90  ? 280 THR A CB  1 
ATOM 1503 O OG1 . THR A 1 280 ? 125.464 135.095 119.369 1.00 96.80  ? 280 THR A OG1 1 
ATOM 1504 C CG2 . THR A 1 280 ? 124.426 133.530 117.868 1.00 89.35  ? 280 THR A CG2 1 
ATOM 1505 N N   . LEU A 1 281 ? 124.106 136.446 115.385 1.00 85.63  ? 281 LEU A N   1 
ATOM 1506 C CA  . LEU A 1 281 ? 123.466 136.605 114.079 1.00 81.34  ? 281 LEU A CA  1 
ATOM 1507 C C   . LEU A 1 281 ? 124.477 136.613 112.950 1.00 82.82  ? 281 LEU A C   1 
ATOM 1508 O O   . LEU A 1 281 ? 124.322 135.889 111.957 1.00 84.04  ? 281 LEU A O   1 
ATOM 1509 C CB  . LEU A 1 281 ? 122.698 137.921 114.024 1.00 78.89  ? 281 LEU A CB  1 
ATOM 1510 C CG  . LEU A 1 281 ? 121.483 138.029 113.106 1.00 74.37  ? 281 LEU A CG  1 
ATOM 1511 C CD1 . LEU A 1 281 ? 120.717 136.713 112.966 1.00 67.87  ? 281 LEU A CD1 1 
ATOM 1512 C CD2 . LEU A 1 281 ? 120.613 139.233 113.454 1.00 73.34  ? 281 LEU A CD2 1 
ATOM 1513 N N   . ALA A 1 282 ? 125.503 137.457 113.081 1.00 84.72  ? 282 ALA A N   1 
ATOM 1514 C CA  . ALA A 1 282 ? 126.515 137.571 112.043 1.00 83.80  ? 282 ALA A CA  1 
ATOM 1515 C C   . ALA A 1 282 ? 127.235 136.251 111.839 1.00 84.91  ? 282 ALA A C   1 
ATOM 1516 O O   . ALA A 1 282 ? 127.359 135.780 110.706 1.00 86.08  ? 282 ALA A O   1 
ATOM 1517 C CB  . ALA A 1 282 ? 127.510 138.676 112.398 1.00 85.48  ? 282 ALA A CB  1 
ATOM 1518 N N   . VAL A 1 283 ? 127.635 135.591 112.927 1.00 87.73  ? 283 VAL A N   1 
ATOM 1519 C CA  . VAL A 1 283 ? 128.481 134.416 112.744 1.00 88.52  ? 283 VAL A CA  1 
ATOM 1520 C C   . VAL A 1 283 ? 127.668 133.198 112.318 1.00 84.51  ? 283 VAL A C   1 
ATOM 1521 O O   . VAL A 1 283 ? 128.246 132.241 111.787 1.00 84.67  ? 283 VAL A O   1 
ATOM 1522 C CB  . VAL A 1 283 ? 129.310 134.162 114.023 1.00 91.85  ? 283 VAL A CB  1 
ATOM 1523 C CG1 . VAL A 1 283 ? 128.435 133.807 115.222 1.00 88.74  ? 283 VAL A CG1 1 
ATOM 1524 C CG2 . VAL A 1 283 ? 130.514 133.230 113.793 1.00 88.54  ? 283 VAL A CG2 1 
ATOM 1525 N N   . VAL A 1 284 ? 126.340 133.208 112.475 1.00 82.13  ? 284 VAL A N   1 
ATOM 1526 C CA  . VAL A 1 284 ? 125.573 132.075 111.945 1.00 79.19  ? 284 VAL A CA  1 
ATOM 1527 C C   . VAL A 1 284 ? 125.115 132.351 110.514 1.00 77.47  ? 284 VAL A C   1 
ATOM 1528 O O   . VAL A 1 284 ? 125.074 131.441 109.684 1.00 81.71  ? 284 VAL A O   1 
ATOM 1529 C CB  . VAL A 1 284 ? 124.368 131.697 112.847 1.00 80.66  ? 284 VAL A CB  1 
ATOM 1530 C CG1 . VAL A 1 284 ? 123.376 132.840 113.029 1.00 79.98  ? 284 VAL A CG1 1 
ATOM 1531 C CG2 . VAL A 1 284 ? 123.669 130.424 112.363 1.00 80.26  ? 284 VAL A CG2 1 
ATOM 1532 N N   . LEU A 1 285 ? 124.801 133.601 110.171 1.00 73.55  ? 285 LEU A N   1 
ATOM 1533 C CA  . LEU A 1 285 ? 124.184 133.862 108.880 1.00 74.59  ? 285 LEU A CA  1 
ATOM 1534 C C   . LEU A 1 285 ? 125.168 134.319 107.815 1.00 80.51  ? 285 LEU A C   1 
ATOM 1535 O O   . LEU A 1 285 ? 124.976 133.994 106.637 1.00 84.66  ? 285 LEU A O   1 
ATOM 1536 C CB  . LEU A 1 285 ? 123.081 134.908 109.028 1.00 72.98  ? 285 LEU A CB  1 
ATOM 1537 C CG  . LEU A 1 285 ? 121.941 134.786 108.024 1.00 71.28  ? 285 LEU A CG  1 
ATOM 1538 C CD1 . LEU A 1 285 ? 121.220 133.465 108.204 1.00 67.04  ? 285 LEU A CD1 1 
ATOM 1539 C CD2 . LEU A 1 285 ? 120.984 135.948 108.184 1.00 67.46  ? 285 LEU A CD2 1 
ATOM 1540 N N   . GLY A 1 286 ? 126.203 135.079 108.180 1.00 79.32  ? 286 GLY A N   1 
ATOM 1541 C CA  . GLY A 1 286 ? 127.140 135.562 107.187 1.00 78.15  ? 286 GLY A CA  1 
ATOM 1542 C C   . GLY A 1 286 ? 127.993 134.466 106.591 1.00 82.15  ? 286 GLY A C   1 
ATOM 1543 O O   . GLY A 1 286 ? 128.433 134.580 105.445 1.00 90.15  ? 286 GLY A O   1 
ATOM 1544 N N   . THR A 1 287 ? 128.225 133.387 107.341 1.00 75.94  ? 287 THR A N   1 
ATOM 1545 C CA  . THR A 1 287 ? 128.939 132.253 106.766 1.00 81.42  ? 287 THR A CA  1 
ATOM 1546 C C   . THR A 1 287 ? 128.113 131.580 105.674 1.00 85.87  ? 287 THR A C   1 
ATOM 1547 O O   . THR A 1 287 ? 128.649 131.234 104.614 1.00 91.53  ? 287 THR A O   1 
ATOM 1548 C CB  . THR A 1 287 ? 129.357 131.266 107.863 1.00 83.05  ? 287 THR A CB  1 
ATOM 1549 O OG1 . THR A 1 287 ? 129.995 130.127 107.272 1.00 86.68  ? 287 THR A OG1 1 
ATOM 1550 C CG2 . THR A 1 287 ? 128.188 130.826 108.739 1.00 81.32  ? 287 THR A CG2 1 
ATOM 1551 N N   . PHE A 1 288 ? 126.800 131.458 105.879 1.00 80.00  ? 288 PHE A N   1 
ATOM 1552 C CA  . PHE A 1 288 ? 125.936 130.911 104.840 1.00 79.36  ? 288 PHE A CA  1 
ATOM 1553 C C   . PHE A 1 288 ? 125.785 131.887 103.682 1.00 79.35  ? 288 PHE A C   1 
ATOM 1554 O O   . PHE A 1 288 ? 125.660 131.473 102.524 1.00 82.96  ? 288 PHE A O   1 
ATOM 1555 C CB  . PHE A 1 288 ? 124.573 130.554 105.426 1.00 74.31  ? 288 PHE A CB  1 
ATOM 1556 C CG  . PHE A 1 288 ? 123.835 129.521 104.639 1.00 76.54  ? 288 PHE A CG  1 
ATOM 1557 C CD1 . PHE A 1 288 ? 124.309 128.225 104.560 1.00 80.37  ? 288 PHE A CD1 1 
ATOM 1558 C CD2 . PHE A 1 288 ? 122.667 129.844 103.973 1.00 76.39  ? 288 PHE A CD2 1 
ATOM 1559 C CE1 . PHE A 1 288 ? 123.631 127.265 103.833 1.00 80.74  ? 288 PHE A CE1 1 
ATOM 1560 C CE2 . PHE A 1 288 ? 121.983 128.892 103.242 1.00 78.28  ? 288 PHE A CE2 1 
ATOM 1561 C CZ  . PHE A 1 288 ? 122.466 127.600 103.173 1.00 80.55  ? 288 PHE A CZ  1 
ATOM 1562 N N   . GLY A 1 289 ? 125.797 133.182 103.973 1.00 78.14  ? 289 GLY A N   1 
ATOM 1563 C CA  . GLY A 1 289 ? 125.676 134.173 102.924 1.00 81.39  ? 289 GLY A CA  1 
ATOM 1564 C C   . GLY A 1 289 ? 126.947 134.462 102.162 1.00 85.23  ? 289 GLY A C   1 
ATOM 1565 O O   . GLY A 1 289 ? 126.889 135.117 101.117 1.00 90.03  ? 289 GLY A O   1 
ATOM 1566 N N   . ALA A 1 290 ? 128.093 134.009 102.662 1.00 81.20  ? 290 ALA A N   1 
ATOM 1567 C CA  . ALA A 1 290 ? 129.364 134.271 102.011 1.00 85.12  ? 290 ALA A CA  1 
ATOM 1568 C C   . ALA A 1 290 ? 130.098 133.012 101.581 1.00 83.72  ? 290 ALA A C   1 
ATOM 1569 O O   . ALA A 1 290 ? 131.147 133.120 100.937 1.00 87.45  ? 290 ALA A O   1 
ATOM 1570 C CB  . ALA A 1 290 ? 130.272 135.099 102.931 1.00 89.49  ? 290 ALA A CB  1 
ATOM 1571 N N   . SER A 1 291 ? 129.592 131.826 101.914 1.00 81.43  ? 291 SER A N   1 
ATOM 1572 C CA  . SER A 1 291 ? 130.230 130.593 101.478 1.00 84.89  ? 291 SER A CA  1 
ATOM 1573 C C   . SER A 1 291 ? 129.540 129.986 100.263 1.00 82.99  ? 291 SER A C   1 
ATOM 1574 O O   . SER A 1 291 ? 130.171 129.792 99.220  1.00 83.71  ? 291 SER A O   1 
ATOM 1575 C CB  . SER A 1 291 ? 130.247 129.593 102.634 1.00 87.03  ? 291 SER A CB  1 
ATOM 1576 O OG  . SER A 1 291 ? 128.932 129.326 103.088 1.00 87.53  ? 291 SER A OG  1 
ATOM 1577 N N   . TRP A 1 292 ? 128.250 129.679 100.378 1.00 78.03  ? 292 TRP A N   1 
ATOM 1578 C CA  . TRP A 1 292 ? 127.547 129.032 99.280  1.00 79.94  ? 292 TRP A CA  1 
ATOM 1579 C C   . TRP A 1 292 ? 127.124 130.009 98.198  1.00 80.90  ? 292 TRP A C   1 
ATOM 1580 O O   . TRP A 1 292 ? 126.778 129.575 97.094  1.00 86.35  ? 292 TRP A O   1 
ATOM 1581 C CB  . TRP A 1 292 ? 126.313 128.301 99.802  1.00 79.77  ? 292 TRP A CB  1 
ATOM 1582 C CG  . TRP A 1 292 ? 126.542 126.875 100.177 1.00 81.55  ? 292 TRP A CG  1 
ATOM 1583 C CD1 . TRP A 1 292 ? 126.449 126.342 101.421 1.00 83.55  ? 292 TRP A CD1 1 
ATOM 1584 C CD2 . TRP A 1 292 ? 126.877 125.792 99.301  1.00 83.92  ? 292 TRP A CD2 1 
ATOM 1585 N NE1 . TRP A 1 292 ? 126.718 124.999 101.387 1.00 83.09  ? 292 TRP A NE1 1 
ATOM 1586 C CE2 . TRP A 1 292 ? 126.983 124.635 100.094 1.00 85.93  ? 292 TRP A CE2 1 
ATOM 1587 C CE3 . TRP A 1 292 ? 127.101 125.689 97.926  1.00 84.60  ? 292 TRP A CE3 1 
ATOM 1588 C CZ2 . TRP A 1 292 ? 127.303 123.390 99.561  1.00 88.64  ? 292 TRP A CZ2 1 
ATOM 1589 C CZ3 . TRP A 1 292 ? 127.418 124.451 97.397  1.00 87.20  ? 292 TRP A CZ3 1 
ATOM 1590 C CH2 . TRP A 1 292 ? 127.517 123.319 98.213  1.00 89.27  ? 292 TRP A CH2 1 
ATOM 1591 N N   . LEU A 1 293 ? 127.128 131.312 98.498  1.00 76.56  ? 293 LEU A N   1 
ATOM 1592 C CA  . LEU A 1 293 ? 126.659 132.299 97.525  1.00 81.02  ? 293 LEU A CA  1 
ATOM 1593 C C   . LEU A 1 293 ? 127.532 132.399 96.274  1.00 80.47  ? 293 LEU A C   1 
ATOM 1594 O O   . LEU A 1 293 ? 126.962 132.471 95.169  1.00 83.68  ? 293 LEU A O   1 
ATOM 1595 C CB  . LEU A 1 293 ? 126.477 133.657 98.211  1.00 82.48  ? 293 LEU A CB  1 
ATOM 1596 C CG  . LEU A 1 293 ? 125.490 134.614 97.549  1.00 85.17  ? 293 LEU A CG  1 
ATOM 1597 C CD1 . LEU A 1 293 ? 124.074 134.121 97.760  1.00 78.53  ? 293 LEU A CD1 1 
ATOM 1598 C CD2 . LEU A 1 293 ? 125.659 136.023 98.092  1.00 89.46  ? 293 LEU A CD2 1 
ATOM 1599 N N   . PRO A 1 294 ? 128.878 132.445 96.346  1.00 72.62  ? 294 PRO A N   1 
ATOM 1600 C CA  . PRO A 1 294 ? 129.646 132.452 95.088  1.00 75.55  ? 294 PRO A CA  1 
ATOM 1601 C C   . PRO A 1 294 ? 129.482 131.194 94.259  1.00 80.95  ? 294 PRO A C   1 
ATOM 1602 O O   . PRO A 1 294 ? 129.610 131.259 93.032  1.00 88.80  ? 294 PRO A O   1 
ATOM 1603 C CB  . PRO A 1 294 ? 131.096 132.629 95.559  1.00 79.27  ? 294 PRO A CB  1 
ATOM 1604 C CG  . PRO A 1 294 ? 131.093 132.188 96.961  1.00 79.38  ? 294 PRO A CG  1 
ATOM 1605 C CD  . PRO A 1 294 ? 129.792 132.675 97.482  1.00 75.50  ? 294 PRO A CD  1 
ATOM 1606 N N   . PHE A 1 295 ? 129.194 130.054 94.890  1.00 78.66  ? 295 PHE A N   1 
ATOM 1607 C CA  . PHE A 1 295 ? 128.964 128.822 94.143  1.00 79.28  ? 295 PHE A CA  1 
ATOM 1608 C C   . PHE A 1 295 ? 127.696 128.951 93.306  1.00 78.33  ? 295 PHE A C   1 
ATOM 1609 O O   . PHE A 1 295 ? 127.686 128.620 92.113  1.00 81.49  ? 295 PHE A O   1 
ATOM 1610 C CB  . PHE A 1 295 ? 128.892 127.652 95.134  1.00 81.66  ? 295 PHE A CB  1 
ATOM 1611 C CG  . PHE A 1 295 ? 129.223 126.288 94.549  1.00 89.63  ? 295 PHE A CG  1 
ATOM 1612 C CD1 . PHE A 1 295 ? 129.994 125.402 95.288  1.00 92.03  ? 295 PHE A CD1 1 
ATOM 1613 C CD2 . PHE A 1 295 ? 128.757 125.874 93.312  1.00 91.21  ? 295 PHE A CD2 1 
ATOM 1614 C CE1 . PHE A 1 295 ? 130.312 124.148 94.795  1.00 93.23  ? 295 PHE A CE1 1 
ATOM 1615 C CE2 . PHE A 1 295 ? 129.070 124.621 92.814  1.00 90.86  ? 295 PHE A CE2 1 
ATOM 1616 C CZ  . PHE A 1 295 ? 129.847 123.758 93.558  1.00 93.71  ? 295 PHE A CZ  1 
ATOM 1617 N N   . ALA A 1 296 ? 126.632 129.483 93.909  1.00 75.99  ? 296 ALA A N   1 
ATOM 1618 C CA  . ALA A 1 296 ? 125.391 129.712 93.180  1.00 79.09  ? 296 ALA A CA  1 
ATOM 1619 C C   . ALA A 1 296 ? 125.574 130.761 92.092  1.00 81.88  ? 296 ALA A C   1 
ATOM 1620 O O   . ALA A 1 296 ? 124.999 130.642 91.002  1.00 85.37  ? 296 ALA A O   1 
ATOM 1621 C CB  . ALA A 1 296 ? 124.287 130.131 94.148  1.00 72.75  ? 296 ALA A CB  1 
ATOM 1622 N N   . ILE A 1 297 ? 126.386 131.786 92.363  1.00 78.90  ? 297 ILE A N   1 
ATOM 1623 C CA  . ILE A 1 297 ? 126.639 132.822 91.365  1.00 81.63  ? 297 ILE A CA  1 
ATOM 1624 C C   . ILE A 1 297 ? 127.368 132.237 90.160  1.00 78.70  ? 297 ILE A C   1 
ATOM 1625 O O   . ILE A 1 297 ? 126.977 132.460 89.007  1.00 81.78  ? 297 ILE A O   1 
ATOM 1626 C CB  . ILE A 1 297 ? 127.421 133.990 91.995  1.00 89.30  ? 297 ILE A CB  1 
ATOM 1627 C CG1 . ILE A 1 297 ? 126.507 134.818 92.900  1.00 89.99  ? 297 ILE A CG1 1 
ATOM 1628 C CG2 . ILE A 1 297 ? 128.044 134.877 90.924  1.00 90.86  ? 297 ILE A CG2 1 
ATOM 1629 C CD1 . ILE A 1 297 ? 125.326 135.433 92.179  1.00 84.28  ? 297 ILE A CD1 1 
ATOM 1630 N N   . TYR A 1 298 ? 128.418 131.452 90.410  1.00 77.20  ? 298 TYR A N   1 
ATOM 1631 C CA  . TYR A 1 298 ? 129.194 130.893 89.310  1.00 79.77  ? 298 TYR A CA  1 
ATOM 1632 C C   . TYR A 1 298 ? 128.385 129.869 88.531  1.00 82.28  ? 298 TYR A C   1 
ATOM 1633 O O   . TYR A 1 298 ? 128.540 129.750 87.311  1.00 84.10  ? 298 TYR A O   1 
ATOM 1634 C CB  . TYR A 1 298 ? 130.490 130.272 89.825  1.00 82.19  ? 298 TYR A CB  1 
ATOM 1635 C CG  . TYR A 1 298 ? 131.608 130.313 88.808  1.00 85.99  ? 298 TYR A CG  1 
ATOM 1636 C CD1 . TYR A 1 298 ? 131.669 129.390 87.772  1.00 85.34  ? 298 TYR A CD1 1 
ATOM 1637 C CD2 . TYR A 1 298 ? 132.597 131.287 88.876  1.00 88.87  ? 298 TYR A CD2 1 
ATOM 1638 C CE1 . TYR A 1 298 ? 132.683 129.431 86.837  1.00 84.91  ? 298 TYR A CE1 1 
ATOM 1639 C CE2 . TYR A 1 298 ? 133.618 131.334 87.945  1.00 91.90  ? 298 TYR A CE2 1 
ATOM 1640 C CZ  . TYR A 1 298 ? 133.655 130.403 86.929  1.00 89.16  ? 298 TYR A CZ  1 
ATOM 1641 O OH  . TYR A 1 298 ? 134.668 130.446 86.000  1.00 91.29  ? 298 TYR A OH  1 
ATOM 1642 N N   . CYS A 1 299 ? 127.508 129.131 89.203  1.00 84.07  ? 299 CYS A N   1 
ATOM 1643 C CA  . CYS A 1 299 ? 126.640 128.234 88.457  1.00 89.65  ? 299 CYS A CA  1 
ATOM 1644 C C   . CYS A 1 299 ? 125.510 128.947 87.725  1.00 87.04  ? 299 CYS A C   1 
ATOM 1645 O O   . CYS A 1 299 ? 124.971 128.383 86.768  1.00 86.35  ? 299 CYS A O   1 
ATOM 1646 C CB  . CYS A 1 299 ? 126.063 127.167 89.381  1.00 91.19  ? 299 CYS A CB  1 
ATOM 1647 S SG  . CYS A 1 299 ? 127.309 126.131 90.144  1.00 104.49 ? 299 CYS A SG  1 
ATOM 1648 N N   . VAL A 1 300 ? 125.141 130.162 88.122  1.00 85.92  ? 300 VAL A N   1 
ATOM 1649 C CA  . VAL A 1 300 ? 124.048 130.835 87.435  1.00 89.34  ? 300 VAL A CA  1 
ATOM 1650 C C   . VAL A 1 300 ? 124.534 131.739 86.301  1.00 88.03  ? 300 VAL A C   1 
ATOM 1651 O O   . VAL A 1 300 ? 123.751 132.029 85.382  1.00 94.58  ? 300 VAL A O   1 
ATOM 1652 C CB  . VAL A 1 300 ? 123.157 131.617 88.433  1.00 91.92  ? 300 VAL A CB  1 
ATOM 1653 C CG1 . VAL A 1 300 ? 123.788 132.934 88.862  1.00 90.82  ? 300 VAL A CG1 1 
ATOM 1654 C CG2 . VAL A 1 300 ? 121.739 131.818 87.887  1.00 90.58  ? 300 VAL A CG2 1 
ATOM 1655 N N   . VAL A 1 301 ? 125.798 132.164 86.308  1.00 81.06  ? 301 VAL A N   1 
ATOM 1656 C CA  . VAL A 1 301 ? 126.297 132.993 85.217  1.00 80.58  ? 301 VAL A CA  1 
ATOM 1657 C C   . VAL A 1 301 ? 127.439 132.354 84.439  1.00 82.85  ? 301 VAL A C   1 
ATOM 1658 O O   . VAL A 1 301 ? 127.750 132.826 83.333  1.00 87.90  ? 301 VAL A O   1 
ATOM 1659 C CB  . VAL A 1 301 ? 126.723 134.394 85.708  1.00 83.25  ? 301 VAL A CB  1 
ATOM 1660 C CG1 . VAL A 1 301 ? 125.562 135.117 86.385  1.00 80.59  ? 301 VAL A CG1 1 
ATOM 1661 C CG2 . VAL A 1 301 ? 127.962 134.326 86.589  1.00 85.87  ? 301 VAL A CG2 1 
ATOM 1662 N N   . GLY A 1 302 ? 128.084 131.306 84.947  1.00 82.71  ? 302 GLY A N   1 
ATOM 1663 C CA  . GLY A 1 302 ? 129.260 130.761 84.306  1.00 88.12  ? 302 GLY A CA  1 
ATOM 1664 C C   . GLY A 1 302 ? 128.946 129.765 83.203  1.00 90.53  ? 302 GLY A C   1 
ATOM 1665 O O   . GLY A 1 302 ? 127.796 129.425 82.928  1.00 90.15  ? 302 GLY A O   1 
ATOM 1666 N N   . SER A 1 303 ? 130.015 129.295 82.563  1.00 90.67  ? 303 SER A N   1 
ATOM 1667 C CA  . SER A 1 303 ? 129.941 128.296 81.509  1.00 92.14  ? 303 SER A CA  1 
ATOM 1668 C C   . SER A 1 303 ? 131.138 127.366 81.641  1.00 91.68  ? 303 SER A C   1 
ATOM 1669 O O   . SER A 1 303 ? 132.146 127.710 82.262  1.00 92.21  ? 303 SER A O   1 
ATOM 1670 C CB  . SER A 1 303 ? 129.907 128.941 80.117  1.00 94.69  ? 303 SER A CB  1 
ATOM 1671 O OG  . SER A 1 303 ? 129.444 128.026 79.140  1.00 92.79  ? 303 SER A OG  1 
ATOM 1672 N N   . HIS A 1 304 ? 131.018 126.174 81.053  1.00 89.06  ? 304 HIS A N   1 
ATOM 1673 C CA  . HIS A 1 304 ? 132.033 125.148 81.266  1.00 90.61  ? 304 HIS A CA  1 
ATOM 1674 C C   . HIS A 1 304 ? 133.321 125.419 80.499  1.00 93.98  ? 304 HIS A C   1 
ATOM 1675 O O   . HIS A 1 304 ? 134.353 124.823 80.823  1.00 96.35  ? 304 HIS A O   1 
ATOM 1676 C CB  . HIS A 1 304 ? 131.485 123.771 80.889  1.00 90.98  ? 304 HIS A CB  1 
ATOM 1677 C CG  . HIS A 1 304 ? 131.293 123.573 79.418  1.00 96.34  ? 304 HIS A CG  1 
ATOM 1678 N ND1 . HIS A 1 304 ? 132.292 123.101 78.594  1.00 99.97  ? 304 HIS A ND1 1 
ATOM 1679 C CD2 . HIS A 1 304 ? 130.216 123.779 78.624  1.00 99.04  ? 304 HIS A CD2 1 
ATOM 1680 C CE1 . HIS A 1 304 ? 131.839 123.026 77.355  1.00 100.68 ? 304 HIS A CE1 1 
ATOM 1681 N NE2 . HIS A 1 304 ? 130.582 123.432 77.346  1.00 103.14 ? 304 HIS A NE2 1 
ATOM 1682 N N   . GLU A 1 305 ? 133.295 126.306 79.504  1.00 92.75  ? 305 GLU A N   1 
ATOM 1683 C CA  . GLU A 1 305 ? 134.512 126.606 78.759  1.00 93.52  ? 305 GLU A CA  1 
ATOM 1684 C C   . GLU A 1 305 ? 135.474 127.486 79.548  1.00 92.76  ? 305 GLU A C   1 
ATOM 1685 O O   . GLU A 1 305 ? 136.632 127.631 79.144  1.00 91.36  ? 305 GLU A O   1 
ATOM 1686 C CB  . GLU A 1 305 ? 134.200 127.275 77.406  1.00 93.78  ? 305 GLU A CB  1 
ATOM 1687 C CG  . GLU A 1 305 ? 133.148 126.640 76.443  1.00 92.02  ? 305 GLU A CG  1 
ATOM 1688 C CD  . GLU A 1 305 ? 131.698 126.559 76.933  1.00 92.76  ? 305 GLU A CD  1 
ATOM 1689 O OE1 . GLU A 1 305 ? 130.822 126.293 76.087  1.00 94.68  ? 305 GLU A OE1 1 
ATOM 1690 O OE2 . GLU A 1 305 ? 131.414 126.770 78.130  1.00 91.95  ? 305 GLU A OE2 1 
ATOM 1691 N N   . ASP A 1 306 ? 135.023 128.075 80.653  1.00 94.09  ? 306 ASP A N   1 
ATOM 1692 C CA  . ASP A 1 306 ? 135.898 128.845 81.519  1.00 97.14  ? 306 ASP A CA  1 
ATOM 1693 C C   . ASP A 1 306 ? 136.869 127.916 82.251  1.00 98.80  ? 306 ASP A C   1 
ATOM 1694 O O   . ASP A 1 306 ? 136.599 126.722 82.405  1.00 101.20 ? 306 ASP A O   1 
ATOM 1695 C CB  . ASP A 1 306 ? 135.066 129.645 82.519  1.00 98.23  ? 306 ASP A CB  1 
ATOM 1696 C CG  . ASP A 1 306 ? 134.306 130.780 81.866  1.00 100.14 ? 306 ASP A CG  1 
ATOM 1697 O OD1 . ASP A 1 306 ? 134.554 131.050 80.672  1.00 97.51  ? 306 ASP A OD1 1 
ATOM 1698 O OD2 . ASP A 1 306 ? 133.462 131.401 82.544  1.00 101.07 ? 306 ASP A OD2 1 
ATOM 1699 N N   . PRO A 1 307 ? 138.024 128.434 82.680  1.00 96.10  ? 307 PRO A N   1 
ATOM 1700 C CA  . PRO A 1 307 ? 138.960 127.606 83.451  1.00 99.04  ? 307 PRO A CA  1 
ATOM 1701 C C   . PRO A 1 307 ? 138.389 127.180 84.798  1.00 99.21  ? 307 PRO A C   1 
ATOM 1702 O O   . PRO A 1 307 ? 137.583 127.882 85.410  1.00 95.61  ? 307 PRO A O   1 
ATOM 1703 C CB  . PRO A 1 307 ? 140.179 128.518 83.625  1.00 99.60  ? 307 PRO A CB  1 
ATOM 1704 C CG  . PRO A 1 307 ? 140.104 129.452 82.479  1.00 97.15  ? 307 PRO A CG  1 
ATOM 1705 C CD  . PRO A 1 307 ? 138.647 129.697 82.251  1.00 94.12  ? 307 PRO A CD  1 
ATOM 1706 N N   . ALA A 1 308 ? 138.830 126.005 85.255  1.00 97.61  ? 308 ALA A N   1 
ATOM 1707 C CA  . ALA A 1 308 ? 138.302 125.382 86.463  1.00 93.76  ? 308 ALA A CA  1 
ATOM 1708 C C   . ALA A 1 308 ? 138.944 125.901 87.741  1.00 91.55  ? 308 ALA A C   1 
ATOM 1709 O O   . ALA A 1 308 ? 138.526 125.488 88.831  1.00 90.51  ? 308 ALA A O   1 
ATOM 1710 C CB  . ALA A 1 308 ? 138.482 123.865 86.392  1.00 90.72  ? 308 ALA A CB  1 
ATOM 1711 N N   . VAL A 1 309 ? 139.949 126.773 87.634  1.00 89.47  ? 309 VAL A N   1 
ATOM 1712 C CA  . VAL A 1 309 ? 140.608 127.300 88.824  1.00 89.33  ? 309 VAL A CA  1 
ATOM 1713 C C   . VAL A 1 309 ? 139.639 128.141 89.644  1.00 88.06  ? 309 VAL A C   1 
ATOM 1714 O O   . VAL A 1 309 ? 139.577 128.015 90.873  1.00 89.65  ? 309 VAL A O   1 
ATOM 1715 C CB  . VAL A 1 309 ? 141.872 128.090 88.435  1.00 94.54  ? 309 VAL A CB  1 
ATOM 1716 C CG1 . VAL A 1 309 ? 143.038 127.140 88.217  1.00 92.40  ? 309 VAL A CG1 1 
ATOM 1717 C CG2 . VAL A 1 309 ? 141.631 128.914 87.175  1.00 96.85  ? 309 VAL A CG2 1 
ATOM 1718 N N   . TYR A 1 310 ? 138.838 128.980 88.978  1.00 88.18  ? 310 TYR A N   1 
ATOM 1719 C CA  . TYR A 1 310 ? 137.824 129.750 89.691  1.00 91.49  ? 310 TYR A CA  1 
ATOM 1720 C C   . TYR A 1 310 ? 136.736 128.850 90.259  1.00 90.34  ? 310 TYR A C   1 
ATOM 1721 O O   . TYR A 1 310 ? 136.196 129.136 91.331  1.00 91.45  ? 310 TYR A O   1 
ATOM 1722 C CB  . TYR A 1 310 ? 137.215 130.815 88.780  1.00 91.78  ? 310 TYR A CB  1 
ATOM 1723 C CG  . TYR A 1 310 ? 138.130 131.299 87.684  1.00 99.27  ? 310 TYR A CG  1 
ATOM 1724 C CD1 . TYR A 1 310 ? 139.205 132.134 87.971  1.00 105.07 ? 310 TYR A CD1 1 
ATOM 1725 C CD2 . TYR A 1 310 ? 137.911 130.945 86.361  1.00 100.88 ? 310 TYR A CD2 1 
ATOM 1726 C CE1 . TYR A 1 310 ? 140.045 132.588 86.972  1.00 108.12 ? 310 TYR A CE1 1 
ATOM 1727 C CE2 . TYR A 1 310 ? 138.744 131.396 85.355  1.00 102.35 ? 310 TYR A CE2 1 
ATOM 1728 C CZ  . TYR A 1 310 ? 139.809 132.216 85.665  1.00 106.89 ? 310 TYR A CZ  1 
ATOM 1729 O OH  . TYR A 1 310 ? 140.640 132.665 84.665  1.00 109.30 ? 310 TYR A OH  1 
ATOM 1730 N N   . THR A 1 311 ? 136.406 127.759 89.559  1.00 87.37  ? 311 THR A N   1 
ATOM 1731 C CA  . THR A 1 311 ? 135.396 126.827 90.053  1.00 83.40  ? 311 THR A CA  1 
ATOM 1732 C C   . THR A 1 311 ? 135.847 126.155 91.343  1.00 83.51  ? 311 THR A C   1 
ATOM 1733 O O   . THR A 1 311 ? 135.075 126.057 92.306  1.00 86.29  ? 311 THR A O   1 
ATOM 1734 C CB  . THR A 1 311 ? 135.083 125.781 88.985  1.00 87.03  ? 311 THR A CB  1 
ATOM 1735 O OG1 . THR A 1 311 ? 134.599 126.434 87.806  1.00 88.73  ? 311 THR A OG1 1 
ATOM 1736 C CG2 . THR A 1 311 ? 134.027 124.808 89.478  1.00 82.23  ? 311 THR A CG2 1 
ATOM 1737 N N   . TYR A 1 312 ? 137.106 125.715 91.394  1.00 83.72  ? 312 TYR A N   1 
ATOM 1738 C CA  . TYR A 1 312 ? 137.640 125.178 92.642  1.00 88.89  ? 312 TYR A CA  1 
ATOM 1739 C C   . TYR A 1 312 ? 137.728 126.259 93.712  1.00 89.18  ? 312 TYR A C   1 
ATOM 1740 O O   . TYR A 1 312 ? 137.490 125.991 94.900  1.00 92.63  ? 312 TYR A O   1 
ATOM 1741 C CB  . TYR A 1 312 ? 139.010 124.550 92.401  1.00 90.21  ? 312 TYR A CB  1 
ATOM 1742 C CG  . TYR A 1 312 ? 138.963 123.221 91.690  1.00 93.30  ? 312 TYR A CG  1 
ATOM 1743 C CD1 . TYR A 1 312 ? 138.219 122.165 92.200  1.00 97.09  ? 312 TYR A CD1 1 
ATOM 1744 C CD2 . TYR A 1 312 ? 139.672 123.017 90.513  1.00 96.84  ? 312 TYR A CD2 1 
ATOM 1745 C CE1 . TYR A 1 312 ? 138.175 120.943 91.552  1.00 102.54 ? 312 TYR A CE1 1 
ATOM 1746 C CE2 . TYR A 1 312 ? 139.635 121.800 89.858  1.00 101.06 ? 312 TYR A CE2 1 
ATOM 1747 C CZ  . TYR A 1 312 ? 138.886 120.767 90.382  1.00 103.83 ? 312 TYR A CZ  1 
ATOM 1748 O OH  . TYR A 1 312 ? 138.848 119.554 89.733  1.00 103.64 ? 312 TYR A OH  1 
ATOM 1749 N N   . ALA A 1 313 ? 138.045 127.492 93.300  1.00 84.94  ? 313 ALA A N   1 
ATOM 1750 C CA  . ALA A 1 313 ? 138.160 128.595 94.246  1.00 87.68  ? 313 ALA A CA  1 
ATOM 1751 C C   . ALA A 1 313 ? 136.830 128.923 94.906  1.00 90.78  ? 313 ALA A C   1 
ATOM 1752 O O   . ALA A 1 313 ? 136.806 129.321 96.075  1.00 93.41  ? 313 ALA A O   1 
ATOM 1753 C CB  . ALA A 1 313 ? 138.722 129.830 93.543  1.00 87.81  ? 313 ALA A CB  1 
ATOM 1754 N N   . THR A 1 314 ? 135.719 128.779 94.186  1.00 90.56  ? 314 THR A N   1 
ATOM 1755 C CA  . THR A 1 314 ? 134.433 129.014 94.830  1.00 90.89  ? 314 THR A CA  1 
ATOM 1756 C C   . THR A 1 314 ? 133.836 127.749 95.428  1.00 87.25  ? 314 THR A C   1 
ATOM 1757 O O   . THR A 1 314 ? 132.859 127.843 96.177  1.00 88.45  ? 314 THR A O   1 
ATOM 1758 C CB  . THR A 1 314 ? 133.402 129.617 93.873  1.00 92.44  ? 314 THR A CB  1 
ATOM 1759 O OG1 . THR A 1 314 ? 132.113 129.519 94.481  1.00 92.25  ? 314 THR A OG1 1 
ATOM 1760 C CG2 . THR A 1 314 ? 133.322 128.824 92.598  1.00 90.20  ? 314 THR A CG2 1 
ATOM 1761 N N   . LEU A 1 315 ? 134.371 126.572 95.105  1.00 83.05  ? 315 LEU A N   1 
ATOM 1762 C CA  . LEU A 1 315 ? 133.893 125.370 95.775  1.00 82.09  ? 315 LEU A CA  1 
ATOM 1763 C C   . LEU A 1 315 ? 134.569 125.189 97.129  1.00 84.58  ? 315 LEU A C   1 
ATOM 1764 O O   . LEU A 1 315 ? 134.026 124.500 97.998  1.00 88.31  ? 315 LEU A O   1 
ATOM 1765 C CB  . LEU A 1 315 ? 134.091 124.158 94.851  1.00 84.81  ? 315 LEU A CB  1 
ATOM 1766 C CG  . LEU A 1 315 ? 133.841 122.669 95.157  1.00 89.54  ? 315 LEU A CG  1 
ATOM 1767 C CD1 . LEU A 1 315 ? 133.803 121.924 93.834  1.00 91.53  ? 315 LEU A CD1 1 
ATOM 1768 C CD2 . LEU A 1 315 ? 134.885 121.999 96.041  1.00 91.56  ? 315 LEU A CD2 1 
ATOM 1769 N N   . LEU A 1 316 ? 135.746 125.787 97.314  1.00 86.44  ? 316 LEU A N   1 
ATOM 1770 C CA  . LEU A 1 316 ? 136.409 125.746 98.618  1.00 90.08  ? 316 LEU A CA  1 
ATOM 1771 C C   . LEU A 1 316 ? 135.610 126.347 99.785  1.00 90.49  ? 316 LEU A C   1 
ATOM 1772 O O   . LEU A 1 316 ? 135.618 125.729 100.868 1.00 94.85  ? 316 LEU A O   1 
ATOM 1773 C CB  . LEU A 1 316 ? 137.792 126.406 98.504  1.00 94.78  ? 316 LEU A CB  1 
ATOM 1774 C CG  . LEU A 1 316 ? 138.673 126.413 99.754  1.00 104.00 ? 316 LEU A CG  1 
ATOM 1775 C CD1 . LEU A 1 316 ? 138.954 124.993 100.222 1.00 105.48 ? 316 LEU A CD1 1 
ATOM 1776 C CD2 . LEU A 1 316 ? 139.971 127.162 99.492  1.00 107.15 ? 316 LEU A CD2 1 
ATOM 1777 N N   . PRO A 1 317 ? 134.937 127.511 99.676  1.00 87.60  ? 317 PRO A N   1 
ATOM 1778 C CA  . PRO A 1 317 ? 134.166 127.996 100.835 1.00 89.84  ? 317 PRO A CA  1 
ATOM 1779 C C   . PRO A 1 317 ? 132.987 127.122 101.218 1.00 86.88  ? 317 PRO A C   1 
ATOM 1780 O O   . PRO A 1 317 ? 132.531 127.219 102.362 1.00 90.63  ? 317 PRO A O   1 
ATOM 1781 C CB  . PRO A 1 317 ? 133.700 129.391 100.396 1.00 89.84  ? 317 PRO A CB  1 
ATOM 1782 C CG  . PRO A 1 317 ? 133.749 129.359 98.940  1.00 88.60  ? 317 PRO A CG  1 
ATOM 1783 C CD  . PRO A 1 317 ? 134.960 128.553 98.633  1.00 88.16  ? 317 PRO A CD  1 
ATOM 1784 N N   . ALA A 1 318 ? 132.479 126.278 100.319 1.00 82.21  ? 318 ALA A N   1 
ATOM 1785 C CA  . ALA A 1 318 ? 131.481 125.297 100.731 1.00 83.93  ? 318 ALA A CA  1 
ATOM 1786 C C   . ALA A 1 318 ? 132.067 124.317 101.738 1.00 83.25  ? 318 ALA A C   1 
ATOM 1787 O O   . ALA A 1 318 ? 131.441 124.010 102.762 1.00 86.30  ? 318 ALA A O   1 
ATOM 1788 C CB  . ALA A 1 318 ? 130.934 124.558 99.511  1.00 88.69  ? 318 ALA A CB  1 
ATOM 1789 N N   . THR A 1 319 ? 133.285 123.845 101.481 1.00 82.75  ? 319 THR A N   1 
ATOM 1790 C CA  . THR A 1 319 ? 133.969 122.997 102.447 1.00 88.43  ? 319 THR A CA  1 
ATOM 1791 C C   . THR A 1 319 ? 134.324 123.766 103.712 1.00 88.12  ? 319 THR A C   1 
ATOM 1792 O O   . THR A 1 319 ? 134.333 123.188 104.803 1.00 92.20  ? 319 THR A O   1 
ATOM 1793 C CB  . THR A 1 319 ? 135.227 122.395 101.822 1.00 98.99  ? 319 THR A CB  1 
ATOM 1794 O OG1 . THR A 1 319 ? 136.058 123.444 101.310 1.00 102.16 ? 319 THR A OG1 1 
ATOM 1795 C CG2 . THR A 1 319 ? 134.854 121.453 100.688 1.00 97.37  ? 319 THR A CG2 1 
ATOM 1796 N N   . TYR A 1 320 ? 134.608 125.065 103.595 1.00 86.65  ? 320 TYR A N   1 
ATOM 1797 C CA  . TYR A 1 320 ? 134.869 125.861 104.792 1.00 89.35  ? 320 TYR A CA  1 
ATOM 1798 C C   . TYR A 1 320 ? 133.616 126.020 105.653 1.00 92.01  ? 320 TYR A C   1 
ATOM 1799 O O   . TYR A 1 320 ? 133.700 126.021 106.886 1.00 93.30  ? 320 TYR A O   1 
ATOM 1800 C CB  . TYR A 1 320 ? 135.432 127.225 104.402 1.00 96.19  ? 320 TYR A CB  1 
ATOM 1801 C CG  . TYR A 1 320 ? 136.939 127.296 104.478 1.00 105.46 ? 320 TYR A CG  1 
ATOM 1802 C CD1 . TYR A 1 320 ? 137.722 126.209 104.108 1.00 106.21 ? 320 TYR A CD1 1 
ATOM 1803 C CD2 . TYR A 1 320 ? 137.579 128.446 104.924 1.00 111.23 ? 320 TYR A CD2 1 
ATOM 1804 C CE1 . TYR A 1 320 ? 139.102 126.267 104.176 1.00 111.93 ? 320 TYR A CE1 1 
ATOM 1805 C CE2 . TYR A 1 320 ? 138.958 128.513 104.997 1.00 114.37 ? 320 TYR A CE2 1 
ATOM 1806 C CZ  . TYR A 1 320 ? 139.714 127.421 104.621 1.00 116.74 ? 320 TYR A CZ  1 
ATOM 1807 O OH  . TYR A 1 320 ? 141.086 127.483 104.692 1.00 119.58 ? 320 TYR A OH  1 
ATOM 1808 N N   . ASN A 1 321 ? 132.447 126.163 105.024 1.00 91.94  ? 321 ASN A N   1 
ATOM 1809 C CA  . ASN A 1 321 ? 131.201 126.258 105.781 1.00 90.23  ? 321 ASN A CA  1 
ATOM 1810 C C   . ASN A 1 321 ? 130.903 124.904 106.412 1.00 87.51  ? 321 ASN A C   1 
ATOM 1811 O O   . ASN A 1 321 ? 130.418 124.829 107.547 1.00 88.24  ? 321 ASN A O   1 
ATOM 1812 C CB  . ASN A 1 321 ? 130.092 126.761 104.831 1.00 88.41  ? 321 ASN A CB  1 
ATOM 1813 C CG  . ASN A 1 321 ? 128.626 126.382 105.214 1.00 89.68  ? 321 ASN A CG  1 
ATOM 1814 O OD1 . ASN A 1 321 ? 128.272 125.997 106.327 1.00 91.89  ? 321 ASN A OD1 1 
ATOM 1815 N ND2 . ASN A 1 321 ? 127.759 126.524 104.227 1.00 88.57  ? 321 ASN A ND2 1 
ATOM 1816 N N   . SER A 1 322 ? 131.206 123.827 105.689 1.00 85.78  ? 322 SER A N   1 
ATOM 1817 C CA  . SER A 1 322 ? 131.098 122.489 106.255 1.00 88.93  ? 322 SER A CA  1 
ATOM 1818 C C   . SER A 1 322 ? 132.038 122.309 107.447 1.00 88.33  ? 322 SER A C   1 
ATOM 1819 O O   . SER A 1 322 ? 131.723 121.573 108.387 1.00 89.21  ? 322 SER A O   1 
ATOM 1820 C CB  . SER A 1 322 ? 131.381 121.470 105.152 1.00 94.77  ? 322 SER A CB  1 
ATOM 1821 O OG  . SER A 1 322 ? 131.572 120.171 105.657 1.00 96.34  ? 322 SER A OG  1 
ATOM 1822 N N   . MET A 1 323 ? 133.185 122.984 107.436 1.00 88.26  ? 323 MET A N   1 
ATOM 1823 C CA  . MET A 1 323 ? 134.049 123.000 108.612 1.00 88.71  ? 323 MET A CA  1 
ATOM 1824 C C   . MET A 1 323 ? 133.421 123.793 109.754 1.00 82.52  ? 323 MET A C   1 
ATOM 1825 O O   . MET A 1 323 ? 133.437 123.350 110.908 1.00 82.51  ? 323 MET A O   1 
ATOM 1826 C CB  . MET A 1 323 ? 135.416 123.583 108.243 1.00 95.73  ? 323 MET A CB  1 
ATOM 1827 C CG  . MET A 1 323 ? 136.246 124.073 109.426 1.00 101.48 ? 323 MET A CG  1 
ATOM 1828 S SD  . MET A 1 323 ? 137.225 122.789 110.224 1.00 121.68 ? 323 MET A SD  1 
ATOM 1829 C CE  . MET A 1 323 ? 138.813 123.069 109.445 1.00 110.09 ? 323 MET A CE  1 
ATOM 1830 N N   . ILE A 1 324 ? 132.847 124.957 109.449 1.00 81.41  ? 324 ILE A N   1 
ATOM 1831 C CA  . ILE A 1 324 ? 132.471 125.901 110.498 1.00 83.82  ? 324 ILE A CA  1 
ATOM 1832 C C   . ILE A 1 324 ? 131.092 125.631 111.097 1.00 81.46  ? 324 ILE A C   1 
ATOM 1833 O O   . ILE A 1 324 ? 130.782 126.166 112.168 1.00 82.60  ? 324 ILE A O   1 
ATOM 1834 C CB  . ILE A 1 324 ? 132.563 127.340 109.955 1.00 88.15  ? 324 ILE A CB  1 
ATOM 1835 C CG1 . ILE A 1 324 ? 132.961 128.316 111.066 1.00 89.45  ? 324 ILE A CG1 1 
ATOM 1836 C CG2 . ILE A 1 324 ? 131.261 127.773 109.291 1.00 87.22  ? 324 ILE A CG2 1 
ATOM 1837 C CD1 . ILE A 1 324 ? 133.684 129.547 110.565 1.00 91.07  ? 324 ILE A CD1 1 
ATOM 1838 N N   . ASN A 1 325 ? 130.256 124.823 110.443 1.00 79.88  ? 325 ASN A N   1 
ATOM 1839 C CA  . ASN A 1 325 ? 128.915 124.557 110.970 1.00 76.49  ? 325 ASN A CA  1 
ATOM 1840 C C   . ASN A 1 325 ? 128.892 123.804 112.303 1.00 74.86  ? 325 ASN A C   1 
ATOM 1841 O O   . ASN A 1 325 ? 128.093 124.194 113.176 1.00 78.26  ? 325 ASN A O   1 
ATOM 1842 C CB  . ASN A 1 325 ? 128.074 123.846 109.905 1.00 79.89  ? 325 ASN A CB  1 
ATOM 1843 C CG  . ASN A 1 325 ? 127.234 124.805 109.097 1.00 80.88  ? 325 ASN A CG  1 
ATOM 1844 O OD1 . ASN A 1 325 ? 126.945 125.915 109.538 1.00 80.89  ? 325 ASN A OD1 1 
ATOM 1845 N ND2 . ASN A 1 325 ? 126.833 124.381 107.905 1.00 80.94  ? 325 ASN A ND2 1 
ATOM 1846 N N   . PRO A 1 326 ? 129.672 122.722 112.528 1.00 77.42  ? 326 PRO A N   1 
ATOM 1847 C CA  . PRO A 1 326 ? 129.678 122.131 113.880 1.00 79.93  ? 326 PRO A CA  1 
ATOM 1848 C C   . PRO A 1 326 ? 130.156 123.078 114.959 1.00 79.49  ? 326 PRO A C   1 
ATOM 1849 O O   . PRO A 1 326 ? 129.580 123.091 116.050 1.00 81.33  ? 326 PRO A O   1 
ATOM 1850 C CB  . PRO A 1 326 ? 130.625 120.933 113.740 1.00 86.87  ? 326 PRO A CB  1 
ATOM 1851 C CG  . PRO A 1 326 ? 130.588 120.593 112.340 1.00 88.28  ? 326 PRO A CG  1 
ATOM 1852 C CD  . PRO A 1 326 ? 130.462 121.879 111.606 1.00 84.01  ? 326 PRO A CD  1 
ATOM 1853 N N   . ILE A 1 327 ? 131.163 123.902 114.664 1.00 79.39  ? 327 ILE A N   1 
ATOM 1854 C CA  . ILE A 1 327 ? 131.658 124.860 115.643 1.00 80.33  ? 327 ILE A CA  1 
ATOM 1855 C C   . ILE A 1 327 ? 130.609 125.923 115.931 1.00 79.60  ? 327 ILE A C   1 
ATOM 1856 O O   . ILE A 1 327 ? 130.539 126.450 117.045 1.00 83.99  ? 327 ILE A O   1 
ATOM 1857 C CB  . ILE A 1 327 ? 132.979 125.479 115.152 1.00 83.22  ? 327 ILE A CB  1 
ATOM 1858 C CG1 . ILE A 1 327 ? 133.869 124.402 114.528 1.00 84.99  ? 327 ILE A CG1 1 
ATOM 1859 C CG2 . ILE A 1 327 ? 133.713 126.164 116.297 1.00 82.29  ? 327 ILE A CG2 1 
ATOM 1860 C CD1 . ILE A 1 327 ? 135.209 124.915 114.040 1.00 83.21  ? 327 ILE A CD1 1 
ATOM 1861 N N   . ILE A 1 328 ? 129.779 126.256 114.944 1.00 78.37  ? 328 ILE A N   1 
ATOM 1862 C CA  . ILE A 1 328 ? 128.715 127.227 115.171 1.00 75.86  ? 328 ILE A CA  1 
ATOM 1863 C C   . ILE A 1 328 ? 127.618 126.630 116.044 1.00 77.48  ? 328 ILE A C   1 
ATOM 1864 O O   . ILE A 1 328 ? 127.167 127.256 117.010 1.00 78.52  ? 328 ILE A O   1 
ATOM 1865 C CB  . ILE A 1 328 ? 128.169 127.744 113.827 1.00 77.60  ? 328 ILE A CB  1 
ATOM 1866 C CG1 . ILE A 1 328 ? 128.976 128.959 113.399 1.00 80.12  ? 328 ILE A CG1 1 
ATOM 1867 C CG2 . ILE A 1 328 ? 126.698 128.133 113.918 1.00 80.45  ? 328 ILE A CG2 1 
ATOM 1868 C CD1 . ILE A 1 328 ? 128.772 130.121 114.320 1.00 81.06  ? 328 ILE A CD1 1 
ATOM 1869 N N   . TYR A 1 329 ? 127.191 125.403 115.746 1.00 80.98  ? 329 TYR A N   1 
ATOM 1870 C CA  . TYR A 1 329 ? 125.975 124.902 116.379 1.00 78.19  ? 329 TYR A CA  1 
ATOM 1871 C C   . TYR A 1 329 ? 126.231 123.962 117.550 1.00 79.90  ? 329 TYR A C   1 
ATOM 1872 O O   . TYR A 1 329 ? 125.693 124.179 118.638 1.00 82.17  ? 329 TYR A O   1 
ATOM 1873 C CB  . TYR A 1 329 ? 125.083 124.219 115.339 1.00 76.01  ? 329 TYR A CB  1 
ATOM 1874 C CG  . TYR A 1 329 ? 124.131 125.185 114.688 1.00 74.52  ? 329 TYR A CG  1 
ATOM 1875 C CD1 . TYR A 1 329 ? 123.084 125.737 115.405 1.00 77.17  ? 329 TYR A CD1 1 
ATOM 1876 C CD2 . TYR A 1 329 ? 124.286 125.557 113.362 1.00 74.65  ? 329 TYR A CD2 1 
ATOM 1877 C CE1 . TYR A 1 329 ? 122.214 126.631 114.819 1.00 78.51  ? 329 TYR A CE1 1 
ATOM 1878 C CE2 . TYR A 1 329 ? 123.425 126.451 112.769 1.00 73.61  ? 329 TYR A CE2 1 
ATOM 1879 C CZ  . TYR A 1 329 ? 122.388 126.982 113.497 1.00 78.50  ? 329 TYR A CZ  1 
ATOM 1880 O OH  . TYR A 1 329 ? 121.521 127.872 112.905 1.00 78.78  ? 329 TYR A OH  1 
ATOM 1881 N N   . ALA A 1 330 ? 127.033 122.919 117.361 1.00 79.86  ? 330 ALA A N   1 
ATOM 1882 C CA  . ALA A 1 330 ? 127.153 121.902 118.394 1.00 86.16  ? 330 ALA A CA  1 
ATOM 1883 C C   . ALA A 1 330 ? 128.173 122.274 119.464 1.00 91.37  ? 330 ALA A C   1 
ATOM 1884 O O   . ALA A 1 330 ? 127.919 122.078 120.655 1.00 97.49  ? 330 ALA A O   1 
ATOM 1885 C CB  . ALA A 1 330 ? 127.523 120.557 117.761 1.00 88.50  ? 330 ALA A CB  1 
ATOM 1886 N N   . PHE A 1 331 ? 129.320 122.823 119.058 1.00 86.78  ? 331 PHE A N   1 
ATOM 1887 C CA  . PHE A 1 331 ? 130.470 122.916 119.951 1.00 88.97  ? 331 PHE A CA  1 
ATOM 1888 C C   . PHE A 1 331 ? 130.298 123.946 121.061 1.00 92.97  ? 331 PHE A C   1 
ATOM 1889 O O   . PHE A 1 331 ? 130.912 123.794 122.121 1.00 98.28  ? 331 PHE A O   1 
ATOM 1890 C CB  . PHE A 1 331 ? 131.727 123.233 119.142 1.00 92.12  ? 331 PHE A CB  1 
ATOM 1891 C CG  . PHE A 1 331 ? 132.440 122.012 118.626 1.00 97.13  ? 331 PHE A CG  1 
ATOM 1892 C CD1 . PHE A 1 331 ? 132.012 120.741 118.976 1.00 99.58  ? 331 PHE A CD1 1 
ATOM 1893 C CD2 . PHE A 1 331 ? 133.537 122.138 117.788 1.00 96.92  ? 331 PHE A CD2 1 
ATOM 1894 C CE1 . PHE A 1 331 ? 132.664 119.619 118.502 1.00 102.85 ? 331 PHE A CE1 1 
ATOM 1895 C CE2 . PHE A 1 331 ? 134.195 121.019 117.309 1.00 98.98  ? 331 PHE A CE2 1 
ATOM 1896 C CZ  . PHE A 1 331 ? 133.757 119.758 117.667 1.00 104.41 ? 331 PHE A CZ  1 
ATOM 1897 N N   . ARG A 1 332 ? 129.493 124.987 120.854 1.00 90.57  ? 332 ARG A N   1 
ATOM 1898 C CA  . ARG A 1 332 ? 129.321 125.996 121.893 1.00 90.97  ? 332 ARG A CA  1 
ATOM 1899 C C   . ARG A 1 332 ? 128.203 125.663 122.867 1.00 94.15  ? 332 ARG A C   1 
ATOM 1900 O O   . ARG A 1 332 ? 128.025 126.390 123.850 1.00 96.03  ? 332 ARG A O   1 
ATOM 1901 C CB  . ARG A 1 332 ? 129.069 127.369 121.267 1.00 89.51  ? 332 ARG A CB  1 
ATOM 1902 C CG  . ARG A 1 332 ? 129.824 127.578 119.978 1.00 88.90  ? 332 ARG A CG  1 
ATOM 1903 C CD  . ARG A 1 332 ? 129.846 129.028 119.537 1.00 88.85  ? 332 ARG A CD  1 
ATOM 1904 N NE  . ARG A 1 332 ? 128.590 129.720 119.790 1.00 95.45  ? 332 ARG A NE  1 
ATOM 1905 C CZ  . ARG A 1 332 ? 128.359 130.983 119.459 1.00 96.99  ? 332 ARG A CZ  1 
ATOM 1906 N NH1 . ARG A 1 332 ? 129.281 131.720 118.863 1.00 95.64  ? 332 ARG A NH1 1 
ATOM 1907 N NH2 . ARG A 1 332 ? 127.171 131.518 119.725 1.00 95.73  ? 332 ARG A NH2 1 
ATOM 1908 N N   . ASN A 1 333 ? 127.446 124.599 122.620 1.00 96.40  ? 333 ASN A N   1 
ATOM 1909 C CA  . ASN A 1 333 ? 126.397 124.210 123.550 1.00 101.57 ? 333 ASN A CA  1 
ATOM 1910 C C   . ASN A 1 333 ? 127.006 123.629 124.820 1.00 105.10 ? 333 ASN A C   1 
ATOM 1911 O O   . ASN A 1 333 ? 128.028 122.936 124.788 1.00 105.85 ? 333 ASN A O   1 
ATOM 1912 C CB  . ASN A 1 333 ? 125.456 123.198 122.903 1.00 104.83 ? 333 ASN A CB  1 
ATOM 1913 C CG  . ASN A 1 333 ? 124.085 123.187 123.547 1.00 111.94 ? 333 ASN A CG  1 
ATOM 1914 O OD1 . ASN A 1 333 ? 123.863 122.511 124.551 1.00 117.20 ? 333 ASN A OD1 1 
ATOM 1915 N ND2 . ASN A 1 333 ? 123.156 123.942 122.972 1.00 111.12 ? 333 ASN A ND2 1 
ATOM 1916 N N   . GLN A 1 334 ? 126.366 123.934 125.952 1.00 103.92 ? 334 GLN A N   1 
ATOM 1917 C CA  . GLN A 1 334 ? 126.901 123.530 127.249 1.00 107.14 ? 334 GLN A CA  1 
ATOM 1918 C C   . GLN A 1 334 ? 126.873 122.017 127.423 1.00 113.09 ? 334 GLN A C   1 
ATOM 1919 O O   . GLN A 1 334 ? 127.830 121.433 127.944 1.00 119.03 ? 334 GLN A O   1 
ATOM 1920 C CB  . GLN A 1 334 ? 126.120 124.215 128.370 1.00 112.48 ? 334 GLN A CB  1 
ATOM 1921 C CG  . GLN A 1 334 ? 126.651 123.933 129.765 1.00 121.12 ? 334 GLN A CG  1 
ATOM 1922 C CD  . GLN A 1 334 ? 125.747 124.475 130.853 1.00 129.62 ? 334 GLN A CD  1 
ATOM 1923 O OE1 . GLN A 1 334 ? 124.701 125.060 130.573 1.00 131.84 ? 334 GLN A OE1 1 
ATOM 1924 N NE2 . GLN A 1 334 ? 126.147 124.284 132.105 1.00 130.30 ? 334 GLN A NE2 1 
ATOM 1925 N N   . GLU A 1 335 ? 125.792 121.365 126.988 1.00 111.79 ? 335 GLU A N   1 
ATOM 1926 C CA  . GLU A 1 335 ? 125.686 119.916 127.132 1.00 111.87 ? 335 GLU A CA  1 
ATOM 1927 C C   . GLU A 1 335 ? 126.706 119.191 126.262 1.00 111.02 ? 335 GLU A C   1 
ATOM 1928 O O   . GLU A 1 335 ? 127.322 118.212 126.704 1.00 114.29 ? 335 GLU A O   1 
ATOM 1929 C CB  . GLU A 1 335 ? 124.269 119.458 126.792 1.00 112.22 ? 335 GLU A CB  1 
ATOM 1930 C CG  . GLU A 1 335 ? 123.298 119.521 127.961 1.00 115.90 ? 335 GLU A CG  1 
ATOM 1931 C CD  . GLU A 1 335 ? 122.855 120.936 128.278 1.00 122.10 ? 335 GLU A CD  1 
ATOM 1932 O OE1 . GLU A 1 335 ? 122.240 121.579 127.401 1.00 127.37 ? 335 GLU A OE1 1 
ATOM 1933 O OE2 . GLU A 1 335 ? 123.122 121.406 129.404 1.00 122.56 ? 335 GLU A OE2 1 
ATOM 1934 N N   . ILE A 1 336 ? 126.910 119.664 125.032 1.00 106.56 ? 336 ILE A N   1 
ATOM 1935 C CA  . ILE A 1 336 ? 127.892 119.043 124.148 1.00 107.92 ? 336 ILE A CA  1 
ATOM 1936 C C   . ILE A 1 336 ? 129.303 119.289 124.664 1.00 113.10 ? 336 ILE A C   1 
ATOM 1937 O O   . ILE A 1 336 ? 130.166 118.404 124.594 1.00 119.84 ? 336 ILE A O   1 
ATOM 1938 C CB  . ILE A 1 336 ? 127.705 119.556 122.710 1.00 104.33 ? 336 ILE A CB  1 
ATOM 1939 C CG1 . ILE A 1 336 ? 126.319 119.181 122.194 1.00 104.41 ? 336 ILE A CG1 1 
ATOM 1940 C CG2 . ILE A 1 336 ? 128.759 118.986 121.773 1.00 101.29 ? 336 ILE A CG2 1 
ATOM 1941 C CD1 . ILE A 1 336 ? 126.087 117.693 122.112 1.00 104.83 ? 336 ILE A CD1 1 
ATOM 1942 N N   . GLN A 1 337 ? 129.557 120.482 125.212 1.00 108.77 ? 337 GLN A N   1 
ATOM 1943 C CA  . GLN A 1 337 ? 130.862 120.763 125.804 1.00 109.34 ? 337 GLN A CA  1 
ATOM 1944 C C   . GLN A 1 337 ? 131.124 119.879 127.017 1.00 116.41 ? 337 GLN A C   1 
ATOM 1945 O O   . GLN A 1 337 ? 132.246 119.396 127.210 1.00 122.35 ? 337 GLN A O   1 
ATOM 1946 C CB  . GLN A 1 337 ? 130.959 122.237 126.187 1.00 107.04 ? 337 GLN A CB  1 
ATOM 1947 C CG  . GLN A 1 337 ? 131.805 123.063 125.240 1.00 106.74 ? 337 GLN A CG  1 
ATOM 1948 C CD  . GLN A 1 337 ? 131.786 124.536 125.581 1.00 109.74 ? 337 GLN A CD  1 
ATOM 1949 O OE1 . GLN A 1 337 ? 131.146 124.953 126.545 1.00 113.66 ? 337 GLN A OE1 1 
ATOM 1950 N NE2 . GLN A 1 337 ? 132.491 125.336 124.789 1.00 106.11 ? 337 GLN A NE2 1 
ATOM 1951 N N   . ARG A 1 338 ? 130.097 119.648 127.839 1.00 116.32 ? 338 ARG A N   1 
ATOM 1952 C CA  . ARG A 1 338 ? 130.248 118.769 128.993 1.00 117.82 ? 338 ARG A CA  1 
ATOM 1953 C C   . ARG A 1 338 ? 130.481 117.326 128.562 1.00 118.21 ? 338 ARG A C   1 
ATOM 1954 O O   . ARG A 1 338 ? 131.297 116.618 129.165 1.00 124.93 ? 338 ARG A O   1 
ATOM 1955 C CB  . ARG A 1 338 ? 129.020 118.888 129.899 1.00 117.46 ? 338 ARG A CB  1 
ATOM 1956 C CG  . ARG A 1 338 ? 128.578 117.600 130.574 1.00 119.71 ? 338 ARG A CG  1 
ATOM 1957 C CD  . ARG A 1 338 ? 127.884 117.886 131.892 1.00 126.94 ? 338 ARG A CD  1 
ATOM 1958 N NE  . ARG A 1 338 ? 128.828 118.166 132.968 1.00 131.53 ? 338 ARG A NE  1 
ATOM 1959 C CZ  . ARG A 1 338 ? 129.488 117.241 133.650 1.00 132.16 ? 338 ARG A CZ  1 
ATOM 1960 N NH1 . ARG A 1 338 ? 129.320 115.950 133.409 1.00 135.28 ? 338 ARG A NH1 1 
ATOM 1961 N NH2 . ARG A 1 338 ? 130.335 117.619 134.604 1.00 128.25 ? 338 ARG A NH2 1 
ATOM 1962 N N   . ALA A 1 339 ? 129.792 116.881 127.507 1.00 114.62 ? 339 ALA A N   1 
ATOM 1963 C CA  . ALA A 1 339 ? 130.015 115.534 126.989 1.00 115.58 ? 339 ALA A CA  1 
ATOM 1964 C C   . ALA A 1 339 ? 131.422 115.381 126.425 1.00 120.56 ? 339 ALA A C   1 
ATOM 1965 O O   . ALA A 1 339 ? 132.064 114.341 126.611 1.00 125.13 ? 339 ALA A O   1 
ATOM 1966 C CB  . ALA A 1 339 ? 128.970 115.201 125.925 1.00 113.91 ? 339 ALA A CB  1 
ATOM 1967 N N   . LEU A 1 340 ? 131.922 116.412 125.739 1.00 120.64 ? 340 LEU A N   1 
ATOM 1968 C CA  . LEU A 1 340 ? 133.281 116.369 125.209 1.00 124.80 ? 340 LEU A CA  1 
ATOM 1969 C C   . LEU A 1 340 ? 134.315 116.371 126.328 1.00 131.06 ? 340 LEU A C   1 
ATOM 1970 O O   . LEU A 1 340 ? 135.339 115.685 126.232 1.00 131.54 ? 340 LEU A O   1 
ATOM 1971 C CB  . LEU A 1 340 ? 133.512 117.547 124.263 1.00 127.45 ? 340 LEU A CB  1 
ATOM 1972 C CG  . LEU A 1 340 ? 134.819 117.558 123.466 1.00 131.28 ? 340 LEU A CG  1 
ATOM 1973 C CD1 . LEU A 1 340 ? 134.540 117.788 121.991 1.00 123.62 ? 340 LEU A CD1 1 
ATOM 1974 C CD2 . LEU A 1 340 ? 135.771 118.619 124.000 1.00 131.73 ? 340 LEU A CD2 1 
ATOM 1975 N N   . TRP A 1 341 ? 134.068 117.141 127.391 1.00 134.59 ? 341 TRP A N   1 
ATOM 1976 C CA  . TRP A 1 341 ? 134.979 117.145 128.533 1.00 137.93 ? 341 TRP A CA  1 
ATOM 1977 C C   . TRP A 1 341 ? 134.963 115.806 129.260 1.00 136.48 ? 341 TRP A C   1 
ATOM 1978 O O   . TRP A 1 341 ? 136.002 115.344 129.745 1.00 137.46 ? 341 TRP A O   1 
ATOM 1979 C CB  . TRP A 1 341 ? 134.615 118.280 129.490 1.00 138.57 ? 341 TRP A CB  1 
ATOM 1980 C CG  . TRP A 1 341 ? 135.382 118.252 130.776 1.00 147.50 ? 341 TRP A CG  1 
ATOM 1981 C CD1 . TRP A 1 341 ? 134.891 117.968 132.016 1.00 150.06 ? 341 TRP A CD1 1 
ATOM 1982 C CD2 . TRP A 1 341 ? 136.780 118.519 130.949 1.00 153.68 ? 341 TRP A CD2 1 
ATOM 1983 N NE1 . TRP A 1 341 ? 135.895 118.041 132.951 1.00 154.81 ? 341 TRP A NE1 1 
ATOM 1984 C CE2 . TRP A 1 341 ? 137.064 118.377 132.322 1.00 156.86 ? 341 TRP A CE2 1 
ATOM 1985 C CE3 . TRP A 1 341 ? 137.817 118.864 130.076 1.00 150.83 ? 341 TRP A CE3 1 
ATOM 1986 C CZ2 . TRP A 1 341 ? 138.343 118.568 132.842 1.00 158.49 ? 341 TRP A CZ2 1 
ATOM 1987 C CZ3 . TRP A 1 341 ? 139.086 119.052 130.596 1.00 151.14 ? 341 TRP A CZ3 1 
ATOM 1988 C CH2 . TRP A 1 341 ? 139.338 118.905 131.965 1.00 155.85 ? 341 TRP A CH2 1 
ATOM 1989 N N   . LEU A 1 342 ? 133.791 115.174 129.353 1.00 134.45 ? 342 LEU A N   1 
ATOM 1990 C CA  . LEU A 1 342 ? 133.699 113.857 129.975 1.00 131.82 ? 342 LEU A CA  1 
ATOM 1991 C C   . LEU A 1 342 ? 134.392 112.798 129.128 1.00 130.21 ? 342 LEU A C   1 
ATOM 1992 O O   . LEU A 1 342 ? 135.006 111.869 129.666 1.00 131.80 ? 342 LEU A O   1 
ATOM 1993 C CB  . LEU A 1 342 ? 132.234 113.491 130.206 1.00 130.12 ? 342 LEU A CB  1 
ATOM 1994 C CG  . LEU A 1 342 ? 131.956 112.227 131.023 1.00 128.44 ? 342 LEU A CG  1 
ATOM 1995 C CD1 . LEU A 1 342 ? 132.207 112.477 132.502 1.00 127.66 ? 342 LEU A CD1 1 
ATOM 1996 C CD2 . LEU A 1 342 ? 130.535 111.739 130.790 1.00 127.69 ? 342 LEU A CD2 1 
ATOM 1997 N N   . LEU A 1 343 ? 134.292 112.913 127.802 1.00 130.59 ? 343 LEU A N   1 
ATOM 1998 C CA  . LEU A 1 343 ? 135.015 112.003 126.920 1.00 134.01 ? 343 LEU A CA  1 
ATOM 1999 C C   . LEU A 1 343 ? 136.520 112.221 127.019 1.00 136.33 ? 343 LEU A C   1 
ATOM 2000 O O   . LEU A 1 343 ? 137.298 111.261 126.975 1.00 135.96 ? 343 LEU A O   1 
ATOM 2001 C CB  . LEU A 1 343 ? 134.537 112.181 125.479 1.00 135.46 ? 343 LEU A CB  1 
ATOM 2002 C CG  . LEU A 1 343 ? 135.148 111.257 124.423 1.00 135.56 ? 343 LEU A CG  1 
ATOM 2003 C CD1 . LEU A 1 343 ? 134.536 109.867 124.505 1.00 132.78 ? 343 LEU A CD1 1 
ATOM 2004 C CD2 . LEU A 1 343 ? 134.974 111.843 123.030 1.00 131.18 ? 343 LEU A CD2 1 
ATOM 2005 N N   . LEU A 1 344 ? 136.948 113.471 127.161 1.00 137.18 ? 344 LEU A N   1 
ATOM 2006 C CA  . LEU A 1 344 ? 138.365 113.788 127.288 1.00 139.34 ? 344 LEU A CA  1 
ATOM 2007 C C   . LEU A 1 344 ? 138.831 113.647 128.733 1.00 135.12 ? 344 LEU A C   1 
ATOM 2008 O O   . LEU A 1 344 ? 138.071 113.220 129.602 1.00 131.92 ? 344 LEU A O   1 
ATOM 2009 C CB  . LEU A 1 344 ? 138.644 115.204 126.782 1.00 139.46 ? 344 LEU A CB  1 
ATOM 2010 C CG  . LEU A 1 344 ? 140.054 115.744 127.029 1.00 138.03 ? 344 LEU A CG  1 
ATOM 2011 C CD1 . LEU A 1 344 ? 141.054 115.091 126.087 1.00 133.68 ? 344 LEU A CD1 1 
ATOM 2012 C CD2 . LEU A 1 344 ? 140.084 117.258 126.884 1.00 136.13 ? 344 LEU A CD2 1 
ATOM 2013 N N   . SER B 2 12  ? 112.883 132.992 187.673 1.00 153.79 ? 2   SER B N   1 
ATOM 2014 C CA  . SER B 2 12  ? 112.758 132.097 188.817 1.00 152.45 ? 2   SER B CA  1 
ATOM 2015 C C   . SER B 2 12  ? 113.032 130.652 188.413 1.00 153.33 ? 2   SER B C   1 
ATOM 2016 O O   . SER B 2 12  ? 114.119 130.128 188.648 1.00 150.22 ? 2   SER B O   1 
ATOM 2017 C CB  . SER B 2 12  ? 111.366 132.215 189.441 1.00 144.44 ? 2   SER B CB  1 
ATOM 2018 N N   . GLU B 2 13  ? 112.033 130.015 187.801 1.00 154.63 ? 3   GLU B N   1 
ATOM 2019 C CA  . GLU B 2 13  ? 112.165 128.611 187.428 1.00 151.71 ? 3   GLU B CA  1 
ATOM 2020 C C   . GLU B 2 13  ? 113.032 128.443 186.186 1.00 144.95 ? 3   GLU B C   1 
ATOM 2021 O O   . GLU B 2 13  ? 113.779 127.464 186.071 1.00 145.11 ? 3   GLU B O   1 
ATOM 2022 C CB  . GLU B 2 13  ? 110.782 128.004 187.195 1.00 152.19 ? 3   GLU B CB  1 
ATOM 2023 C CG  . GLU B 2 13  ? 110.568 126.651 187.851 1.00 154.27 ? 3   GLU B CG  1 
ATOM 2024 C CD  . GLU B 2 13  ? 110.874 126.671 189.336 1.00 156.99 ? 3   GLU B CD  1 
ATOM 2025 O OE1 . GLU B 2 13  ? 110.091 127.279 190.096 1.00 157.20 ? 3   GLU B OE1 1 
ATOM 2026 O OE2 . GLU B 2 13  ? 111.894 126.079 189.745 1.00 155.97 ? 3   GLU B OE2 1 
ATOM 2027 N N   . LEU B 2 14  ? 112.940 129.388 185.246 1.00 141.22 ? 4   LEU B N   1 
ATOM 2028 C CA  . LEU B 2 14  ? 113.582 129.226 183.945 1.00 139.60 ? 4   LEU B CA  1 
ATOM 2029 C C   . LEU B 2 14  ? 115.102 129.279 184.067 1.00 143.07 ? 4   LEU B C   1 
ATOM 2030 O O   . LEU B 2 14  ? 115.806 128.471 183.450 1.00 141.42 ? 4   LEU B O   1 
ATOM 2031 C CB  . LEU B 2 14  ? 113.068 130.306 182.987 1.00 136.15 ? 4   LEU B CB  1 
ATOM 2032 C CG  . LEU B 2 14  ? 113.595 130.584 181.569 1.00 133.24 ? 4   LEU B CG  1 
ATOM 2033 C CD1 . LEU B 2 14  ? 114.051 129.335 180.811 1.00 136.72 ? 4   LEU B CD1 1 
ATOM 2034 C CD2 . LEU B 2 14  ? 112.550 131.346 180.762 1.00 120.96 ? 4   LEU B CD2 1 
ATOM 2035 N N   . ASP B 2 15  ? 115.626 130.210 184.867 1.00 148.06 ? 5   ASP B N   1 
ATOM 2036 C CA  . ASP B 2 15  ? 117.075 130.345 184.992 1.00 153.03 ? 5   ASP B CA  1 
ATOM 2037 C C   . ASP B 2 15  ? 117.690 129.160 185.728 1.00 153.24 ? 5   ASP B C   1 
ATOM 2038 O O   . ASP B 2 15  ? 118.767 128.684 185.350 1.00 149.75 ? 5   ASP B O   1 
ATOM 2039 C CB  . ASP B 2 15  ? 117.426 131.659 185.689 1.00 156.91 ? 5   ASP B CB  1 
ATOM 2040 C CG  . ASP B 2 15  ? 116.607 131.892 186.936 1.00 156.90 ? 5   ASP B CG  1 
ATOM 2041 O OD1 . ASP B 2 15  ? 115.373 132.019 186.810 1.00 152.71 ? 5   ASP B OD1 1 
ATOM 2042 O OD2 . ASP B 2 15  ? 117.193 131.949 188.038 1.00 159.99 ? 5   ASP B OD2 1 
ATOM 2043 N N   . GLN B 2 16  ? 117.023 128.659 186.773 1.00 154.34 ? 6   GLN B N   1 
ATOM 2044 C CA  . GLN B 2 16  ? 117.563 127.500 187.478 1.00 149.84 ? 6   GLN B CA  1 
ATOM 2045 C C   . GLN B 2 16  ? 117.438 126.237 186.633 1.00 144.79 ? 6   GLN B C   1 
ATOM 2046 O O   . GLN B 2 16  ? 118.309 125.362 186.691 1.00 138.56 ? 6   GLN B O   1 
ATOM 2047 C CB  . GLN B 2 16  ? 116.892 127.336 188.848 1.00 148.49 ? 6   GLN B CB  1 
ATOM 2048 C CG  . GLN B 2 16  ? 115.384 127.111 188.856 1.00 148.62 ? 6   GLN B CG  1 
ATOM 2049 C CD  . GLN B 2 16  ? 114.999 125.650 188.719 1.00 151.50 ? 6   GLN B CD  1 
ATOM 2050 O OE1 . GLN B 2 16  ? 115.831 124.759 188.885 1.00 150.71 ? 6   GLN B OE1 1 
ATOM 2051 N NE2 . GLN B 2 16  ? 113.735 125.399 188.401 1.00 152.89 ? 6   GLN B NE2 1 
ATOM 2052 N N   . LEU B 2 17  ? 116.378 126.135 185.822 1.00 146.81 ? 7   LEU B N   1 
ATOM 2053 C CA  . LEU B 2 17  ? 116.275 125.018 184.886 1.00 143.43 ? 7   LEU B CA  1 
ATOM 2054 C C   . LEU B 2 17  ? 117.376 125.077 183.835 1.00 138.07 ? 7   LEU B C   1 
ATOM 2055 O O   . LEU B 2 17  ? 117.966 124.046 183.487 1.00 138.78 ? 7   LEU B O   1 
ATOM 2056 C CB  . LEU B 2 17  ? 114.899 125.010 184.222 1.00 144.70 ? 7   LEU B CB  1 
ATOM 2057 C CG  . LEU B 2 17  ? 113.763 124.347 185.005 1.00 144.12 ? 7   LEU B CG  1 
ATOM 2058 C CD1 . LEU B 2 17  ? 112.409 124.831 184.505 1.00 139.79 ? 7   LEU B CD1 1 
ATOM 2059 C CD2 . LEU B 2 17  ? 113.858 122.834 184.926 1.00 139.49 ? 7   LEU B CD2 1 
ATOM 2060 N N   . ARG B 2 18  ? 117.680 126.277 183.335 1.00 137.01 ? 8   ARG B N   1 
ATOM 2061 C CA  . ARG B 2 18  ? 118.751 126.429 182.357 1.00 143.60 ? 8   ARG B CA  1 
ATOM 2062 C C   . ARG B 2 18  ? 120.115 126.124 182.966 1.00 145.55 ? 8   ARG B C   1 
ATOM 2063 O O   . ARG B 2 18  ? 120.967 125.512 182.312 1.00 143.96 ? 8   ARG B O   1 
ATOM 2064 C CB  . ARG B 2 18  ? 118.727 127.838 181.767 1.00 146.19 ? 8   ARG B CB  1 
ATOM 2065 C CG  . ARG B 2 18  ? 117.743 128.008 180.623 1.00 146.07 ? 8   ARG B CG  1 
ATOM 2066 C CD  . ARG B 2 18  ? 117.919 129.352 179.938 1.00 150.01 ? 8   ARG B CD  1 
ATOM 2067 N NE  . ARG B 2 18  ? 116.907 129.577 178.912 1.00 154.71 ? 8   ARG B NE  1 
ATOM 2068 C CZ  . ARG B 2 18  ? 117.008 129.165 177.656 1.00 153.87 ? 8   ARG B CZ  1 
ATOM 2069 N NH1 . ARG B 2 18  ? 118.070 128.501 177.229 1.00 154.23 ? 8   ARG B NH1 1 
ATOM 2070 N NH2 . ARG B 2 18  ? 116.019 129.425 176.806 1.00 149.33 ? 8   ARG B NH2 1 
ATOM 2071 N N   . GLN B 2 19  ? 120.343 126.532 184.217 1.00 146.37 ? 9   GLN B N   1 
ATOM 2072 C CA  . GLN B 2 19  ? 121.627 126.234 184.844 1.00 147.49 ? 9   GLN B CA  1 
ATOM 2073 C C   . GLN B 2 19  ? 121.743 124.755 185.201 1.00 144.79 ? 9   GLN B C   1 
ATOM 2074 O O   . GLN B 2 19  ? 122.846 124.198 185.163 1.00 141.22 ? 9   GLN B O   1 
ATOM 2075 C CB  . GLN B 2 19  ? 121.850 127.136 186.065 1.00 149.48 ? 9   GLN B CB  1 
ATOM 2076 C CG  . GLN B 2 19  ? 121.246 126.668 187.382 1.00 151.77 ? 9   GLN B CG  1 
ATOM 2077 C CD  . GLN B 2 19  ? 122.279 126.076 188.320 1.00 151.06 ? 9   GLN B CD  1 
ATOM 2078 O OE1 . GLN B 2 19  ? 123.425 126.524 188.363 1.00 149.94 ? 9   GLN B OE1 1 
ATOM 2079 N NE2 . GLN B 2 19  ? 121.877 125.062 189.078 1.00 151.32 ? 9   GLN B NE2 1 
ATOM 2080 N N   . GLU B 2 20  ? 120.620 124.090 185.495 1.00 143.43 ? 10  GLU B N   1 
ATOM 2081 C CA  . GLU B 2 20  ? 120.644 122.643 185.673 1.00 141.86 ? 10  GLU B CA  1 
ATOM 2082 C C   . GLU B 2 20  ? 120.952 121.940 184.359 1.00 136.14 ? 10  GLU B C   1 
ATOM 2083 O O   . GLU B 2 20  ? 121.693 120.951 184.337 1.00 132.51 ? 10  GLU B O   1 
ATOM 2084 C CB  . GLU B 2 20  ? 119.311 122.161 186.242 1.00 147.11 ? 10  GLU B CB  1 
ATOM 2085 C CG  . GLU B 2 20  ? 119.323 120.718 186.717 1.00 152.15 ? 10  GLU B CG  1 
ATOM 2086 C CD  . GLU B 2 20  ? 117.942 120.092 186.713 1.00 155.54 ? 10  GLU B CD  1 
ATOM 2087 O OE1 . GLU B 2 20  ? 116.967 120.797 187.045 1.00 156.93 ? 10  GLU B OE1 1 
ATOM 2088 O OE2 . GLU B 2 20  ? 117.833 118.893 186.378 1.00 152.72 ? 10  GLU B OE2 1 
ATOM 2089 N N   . ALA B 2 21  ? 120.396 122.448 183.255 1.00 134.73 ? 11  ALA B N   1 
ATOM 2090 C CA  . ALA B 2 21  ? 120.701 121.894 181.940 1.00 131.67 ? 11  ALA B CA  1 
ATOM 2091 C C   . ALA B 2 21  ? 122.168 122.092 181.583 1.00 131.52 ? 11  ALA B C   1 
ATOM 2092 O O   . ALA B 2 21  ? 122.798 121.201 181.004 1.00 131.56 ? 11  ALA B O   1 
ATOM 2093 C CB  . ALA B 2 21  ? 119.801 122.529 180.881 1.00 129.10 ? 11  ALA B CB  1 
ATOM 2094 N N   . GLU B 2 22  ? 122.728 123.254 181.927 1.00 134.74 ? 12  GLU B N   1 
ATOM 2095 C CA  . GLU B 2 22  ? 124.146 123.505 181.679 1.00 138.78 ? 12  GLU B CA  1 
ATOM 2096 C C   . GLU B 2 22  ? 125.033 122.600 182.529 1.00 134.70 ? 12  GLU B C   1 
ATOM 2097 O O   . GLU B 2 22  ? 126.061 122.107 182.050 1.00 128.99 ? 12  GLU B O   1 
ATOM 2098 C CB  . GLU B 2 22  ? 124.472 124.975 181.943 1.00 141.41 ? 12  GLU B CB  1 
ATOM 2099 C CG  . GLU B 2 22  ? 123.956 125.928 180.878 1.00 144.23 ? 12  GLU B CG  1 
ATOM 2100 C CD  . GLU B 2 22  ? 124.436 125.563 179.487 1.00 147.42 ? 12  GLU B CD  1 
ATOM 2101 O OE1 . GLU B 2 22  ? 125.655 125.353 179.312 1.00 148.41 ? 12  GLU B OE1 1 
ATOM 2102 O OE2 . GLU B 2 22  ? 123.594 125.486 178.568 1.00 143.84 ? 12  GLU B OE2 1 
ATOM 2103 N N   . GLN B 2 23  ? 124.650 122.374 183.790 1.00 135.01 ? 13  GLN B N   1 
ATOM 2104 C CA  . GLN B 2 23  ? 125.410 121.475 184.655 1.00 133.91 ? 13  GLN B CA  1 
ATOM 2105 C C   . GLN B 2 23  ? 125.353 120.048 184.123 1.00 129.07 ? 13  GLN B C   1 
ATOM 2106 O O   . GLN B 2 23  ? 126.369 119.339 184.113 1.00 126.23 ? 13  GLN B O   1 
ATOM 2107 C CB  . GLN B 2 23  ? 124.866 121.587 186.091 1.00 136.06 ? 13  GLN B CB  1 
ATOM 2108 C CG  . GLN B 2 23  ? 124.595 120.315 186.940 1.00 137.36 ? 13  GLN B CG  1 
ATOM 2109 C CD  . GLN B 2 23  ? 125.811 119.423 187.188 1.00 142.96 ? 13  GLN B CD  1 
ATOM 2110 O OE1 . GLN B 2 23  ? 126.956 119.861 187.069 1.00 146.10 ? 13  GLN B OE1 1 
ATOM 2111 N NE2 . GLN B 2 23  ? 125.559 118.167 187.537 1.00 143.26 ? 13  GLN B NE2 1 
ATOM 2112 N N   . LEU B 2 24  ? 124.177 119.621 183.655 1.00 128.43 ? 14  LEU B N   1 
ATOM 2113 C CA  . LEU B 2 24  ? 124.041 118.295 183.062 1.00 125.67 ? 14  LEU B CA  1 
ATOM 2114 C C   . LEU B 2 24  ? 124.879 118.164 181.799 1.00 120.00 ? 14  LEU B C   1 
ATOM 2115 O O   . LEU B 2 24  ? 125.550 117.147 181.599 1.00 121.55 ? 14  LEU B O   1 
ATOM 2116 C CB  . LEU B 2 24  ? 122.572 118.004 182.760 1.00 128.70 ? 14  LEU B CB  1 
ATOM 2117 C CG  . LEU B 2 24  ? 121.821 117.077 183.721 1.00 133.81 ? 14  LEU B CG  1 
ATOM 2118 C CD1 . LEU B 2 24  ? 122.326 115.649 183.593 1.00 134.28 ? 14  LEU B CD1 1 
ATOM 2119 C CD2 . LEU B 2 24  ? 121.931 117.560 185.160 1.00 133.95 ? 14  LEU B CD2 1 
ATOM 2120 N N   . LYS B 2 25  ? 124.868 119.193 180.947 1.00 118.67 ? 15  LYS B N   1 
ATOM 2121 C CA  . LYS B 2 25  ? 125.649 119.159 179.715 1.00 120.01 ? 15  LYS B CA  1 
ATOM 2122 C C   . LYS B 2 25  ? 127.144 119.117 180.002 1.00 122.77 ? 15  LYS B C   1 
ATOM 2123 O O   . LYS B 2 25  ? 127.889 118.401 179.322 1.00 123.15 ? 15  LYS B O   1 
ATOM 2124 C CB  . LYS B 2 25  ? 125.305 120.366 178.846 1.00 125.50 ? 15  LYS B CB  1 
ATOM 2125 C CG  . LYS B 2 25  ? 124.027 120.206 178.042 1.00 125.05 ? 15  LYS B CG  1 
ATOM 2126 C CD  . LYS B 2 25  ? 123.819 121.379 177.096 1.00 126.02 ? 15  LYS B CD  1 
ATOM 2127 C CE  . LYS B 2 25  ? 124.991 121.534 176.139 1.00 123.66 ? 15  LYS B CE  1 
ATOM 2128 N NZ  . LYS B 2 25  ? 124.618 122.314 174.927 1.00 123.85 ? 15  LYS B NZ  1 
ATOM 2129 N N   . ASN B 2 26  ? 127.599 119.870 181.009 1.00 123.59 ? 16  ASN B N   1 
ATOM 2130 C CA  . ASN B 2 26  ? 129.005 119.824 181.401 1.00 125.58 ? 16  ASN B CA  1 
ATOM 2131 C C   . ASN B 2 26  ? 129.383 118.451 181.944 1.00 121.97 ? 16  ASN B C   1 
ATOM 2132 O O   . ASN B 2 26  ? 130.473 117.940 181.655 1.00 117.11 ? 16  ASN B O   1 
ATOM 2133 C CB  . ASN B 2 26  ? 129.295 120.911 182.435 1.00 129.53 ? 16  ASN B CB  1 
ATOM 2134 C CG  . ASN B 2 26  ? 130.647 121.565 182.231 1.00 132.34 ? 16  ASN B CG  1 
ATOM 2135 O OD1 . ASN B 2 26  ? 131.314 121.336 181.221 1.00 129.16 ? 16  ASN B OD1 1 
ATOM 2136 N ND2 . ASN B 2 26  ? 131.059 122.387 183.190 1.00 130.84 ? 16  ASN B ND2 1 
ATOM 2137 N N   . GLN B 2 27  ? 128.483 117.835 182.720 1.00 122.68 ? 17  GLN B N   1 
ATOM 2138 C CA  . GLN B 2 27  ? 128.730 116.491 183.232 1.00 120.42 ? 17  GLN B CA  1 
ATOM 2139 C C   . GLN B 2 27  ? 128.836 115.475 182.100 1.00 118.67 ? 17  GLN B C   1 
ATOM 2140 O O   . GLN B 2 27  ? 129.717 114.608 182.115 1.00 119.22 ? 17  GLN B O   1 
ATOM 2141 C CB  . GLN B 2 27  ? 127.618 116.104 184.210 1.00 121.74 ? 17  GLN B CB  1 
ATOM 2142 C CG  . GLN B 2 27  ? 127.460 114.612 184.470 1.00 121.49 ? 17  GLN B CG  1 
ATOM 2143 C CD  . GLN B 2 27  ? 128.488 114.068 185.450 1.00 129.48 ? 17  GLN B CD  1 
ATOM 2144 O OE1 . GLN B 2 27  ? 129.680 113.997 185.151 1.00 130.08 ? 17  GLN B OE1 1 
ATOM 2145 N NE2 . GLN B 2 27  ? 128.025 113.684 186.635 1.00 132.18 ? 17  GLN B NE2 1 
ATOM 2146 N N   . ILE B 2 28  ? 127.960 115.581 181.098 1.00 119.16 ? 18  ILE B N   1 
ATOM 2147 C CA  . ILE B 2 28  ? 127.994 114.644 179.977 1.00 115.68 ? 18  ILE B CA  1 
ATOM 2148 C C   . ILE B 2 28  ? 129.233 114.863 179.113 1.00 111.74 ? 18  ILE B C   1 
ATOM 2149 O O   . ILE B 2 28  ? 129.828 113.902 178.613 1.00 110.22 ? 18  ILE B O   1 
ATOM 2150 C CB  . ILE B 2 28  ? 126.690 114.731 179.163 1.00 115.54 ? 18  ILE B CB  1 
ATOM 2151 C CG1 . ILE B 2 28  ? 125.501 114.402 180.062 1.00 116.23 ? 18  ILE B CG1 1 
ATOM 2152 C CG2 . ILE B 2 28  ? 126.711 113.799 177.971 1.00 114.18 ? 18  ILE B CG2 1 
ATOM 2153 C CD1 . ILE B 2 28  ? 125.309 112.928 180.294 1.00 110.05 ? 18  ILE B CD1 1 
ATOM 2154 N N   . ARG B 2 29  ? 129.651 116.118 178.931 1.00 112.93 ? 19  ARG B N   1 
ATOM 2155 C CA  . ARG B 2 29  ? 130.889 116.379 178.199 1.00 116.06 ? 19  ARG B CA  1 
ATOM 2156 C C   . ARG B 2 29  ? 132.100 115.817 178.935 1.00 118.69 ? 19  ARG B C   1 
ATOM 2157 O O   . ARG B 2 29  ? 133.004 115.246 178.309 1.00 118.00 ? 19  ARG B O   1 
ATOM 2158 C CB  . ARG B 2 29  ? 131.056 117.879 177.958 1.00 122.08 ? 19  ARG B CB  1 
ATOM 2159 C CG  . ARG B 2 29  ? 130.122 118.443 176.898 1.00 125.11 ? 19  ARG B CG  1 
ATOM 2160 C CD  . ARG B 2 29  ? 130.541 119.844 176.484 1.00 130.85 ? 19  ARG B CD  1 
ATOM 2161 N NE  . ARG B 2 29  ? 130.511 120.776 177.605 1.00 134.81 ? 19  ARG B NE  1 
ATOM 2162 C CZ  . ARG B 2 29  ? 129.436 121.448 177.992 1.00 132.68 ? 19  ARG B CZ  1 
ATOM 2163 N NH1 . ARG B 2 29  ? 128.276 121.314 177.371 1.00 129.91 ? 19  ARG B NH1 1 
ATOM 2164 N NH2 . ARG B 2 29  ? 129.527 122.277 179.028 1.00 130.00 ? 19  ARG B NH2 1 
ATOM 2165 N N   . ASP B 2 30  ? 132.123 115.947 180.265 1.00 123.54 ? 20  ASP B N   1 
ATOM 2166 C CA  . ASP B 2 30  ? 133.194 115.349 181.056 1.00 126.10 ? 20  ASP B CA  1 
ATOM 2167 C C   . ASP B 2 30  ? 133.170 113.827 180.960 1.00 120.47 ? 20  ASP B C   1 
ATOM 2168 O O   . ASP B 2 30  ? 134.226 113.186 180.901 1.00 116.57 ? 20  ASP B O   1 
ATOM 2169 C CB  . ASP B 2 30  ? 133.077 115.799 182.512 1.00 131.01 ? 20  ASP B CB  1 
ATOM 2170 C CG  . ASP B 2 30  ? 134.381 115.664 183.272 1.00 136.48 ? 20  ASP B CG  1 
ATOM 2171 O OD1 . ASP B 2 30  ? 135.427 115.432 182.630 1.00 136.40 ? 20  ASP B OD1 1 
ATOM 2172 O OD2 . ASP B 2 30  ? 134.360 115.799 184.514 1.00 139.69 ? 20  ASP B OD2 1 
ATOM 2173 N N   . ALA B 2 31  ? 131.974 113.235 180.941 1.00 118.24 ? 21  ALA B N   1 
ATOM 2174 C CA  . ALA B 2 31  ? 131.863 111.785 180.816 1.00 116.33 ? 21  ALA B CA  1 
ATOM 2175 C C   . ALA B 2 31  ? 132.303 111.311 179.437 1.00 116.81 ? 21  ALA B C   1 
ATOM 2176 O O   . ALA B 2 31  ? 132.871 110.221 179.303 1.00 117.82 ? 21  ALA B O   1 
ATOM 2177 C CB  . ALA B 2 31  ? 130.430 111.343 181.105 1.00 114.73 ? 21  ALA B CB  1 
ATOM 2178 N N   . ARG B 2 32  ? 132.030 112.108 178.401 1.00 114.47 ? 22  ARG B N   1 
ATOM 2179 C CA  . ARG B 2 32  ? 132.553 111.815 177.070 1.00 114.27 ? 22  ARG B CA  1 
ATOM 2180 C C   . ARG B 2 32  ? 134.073 111.859 177.061 1.00 114.71 ? 22  ARG B C   1 
ATOM 2181 O O   . ARG B 2 32  ? 134.731 110.982 176.491 1.00 118.07 ? 22  ARG B O   1 
ATOM 2182 C CB  . ARG B 2 32  ? 132.012 112.811 176.045 1.00 115.74 ? 22  ARG B CB  1 
ATOM 2183 C CG  . ARG B 2 32  ? 131.158 112.212 174.946 1.00 116.44 ? 22  ARG B CG  1 
ATOM 2184 C CD  . ARG B 2 32  ? 130.509 113.302 174.106 1.00 118.87 ? 22  ARG B CD  1 
ATOM 2185 N NE  . ARG B 2 32  ? 129.207 113.756 174.572 1.00 121.82 ? 22  ARG B NE  1 
ATOM 2186 C CZ  . ARG B 2 32  ? 128.064 113.148 174.289 1.00 124.00 ? 22  ARG B CZ  1 
ATOM 2187 N NH1 . ARG B 2 32  ? 128.035 112.022 173.598 1.00 125.86 ? 22  ARG B NH1 1 
ATOM 2188 N NH2 . ARG B 2 32  ? 126.921 113.698 174.683 1.00 119.77 ? 22  ARG B NH2 1 
ATOM 2189 N N   . LYS B 2 33  ? 134.647 112.886 177.690 1.00 116.41 ? 23  LYS B N   1 
ATOM 2190 C CA  . LYS B 2 33  ? 136.093 113.060 177.678 1.00 120.35 ? 23  LYS B CA  1 
ATOM 2191 C C   . LYS B 2 33  ? 136.809 112.029 178.539 1.00 122.03 ? 23  LYS B C   1 
ATOM 2192 O O   . LYS B 2 33  ? 137.988 111.749 178.296 1.00 124.60 ? 23  LYS B O   1 
ATOM 2193 C CB  . LYS B 2 33  ? 136.448 114.473 178.143 1.00 121.64 ? 23  LYS B CB  1 
ATOM 2194 C CG  . LYS B 2 33  ? 137.829 114.947 177.720 1.00 122.66 ? 23  LYS B CG  1 
ATOM 2195 C CD  . LYS B 2 33  ? 137.943 115.048 176.209 1.00 120.10 ? 23  LYS B CD  1 
ATOM 2196 C CE  . LYS B 2 33  ? 139.376 115.331 175.791 1.00 113.00 ? 23  LYS B CE  1 
ATOM 2197 N NZ  . LYS B 2 33  ? 139.854 116.642 176.310 1.00 111.12 ? 23  LYS B NZ  1 
ATOM 2198 N N   . ALA B 2 34  ? 136.125 111.461 179.535 1.00 121.13 ? 24  ALA B N   1 
ATOM 2199 C CA  . ALA B 2 34  ? 136.757 110.474 180.405 1.00 124.88 ? 24  ALA B CA  1 
ATOM 2200 C C   . ALA B 2 34  ? 137.076 109.185 179.657 1.00 123.53 ? 24  ALA B C   1 
ATOM 2201 O O   . ALA B 2 34  ? 138.144 108.595 179.854 1.00 124.51 ? 24  ALA B O   1 
ATOM 2202 C CB  . ALA B 2 34  ? 135.860 110.186 181.607 1.00 123.84 ? 24  ALA B CB  1 
ATOM 2203 N N   . CYS B 2 35  ? 136.170 108.735 178.794 1.00 123.80 ? 25  CYS B N   1 
ATOM 2204 C CA  . CYS B 2 35  ? 136.332 107.467 178.097 1.00 126.84 ? 25  CYS B CA  1 
ATOM 2205 C C   . CYS B 2 35  ? 137.077 107.602 176.777 1.00 128.52 ? 25  CYS B C   1 
ATOM 2206 O O   . CYS B 2 35  ? 137.226 106.606 176.064 1.00 131.17 ? 25  CYS B O   1 
ATOM 2207 C CB  . CYS B 2 35  ? 134.965 106.822 177.849 1.00 132.93 ? 25  CYS B CB  1 
ATOM 2208 S SG  . CYS B 2 35  ? 133.808 107.851 176.917 1.00 142.24 ? 25  CYS B SG  1 
ATOM 2209 N N   . ALA B 2 36  ? 137.540 108.801 176.429 1.00 125.00 ? 26  ALA B N   1 
ATOM 2210 C CA  . ALA B 2 36  ? 138.286 109.007 175.188 1.00 129.61 ? 26  ALA B CA  1 
ATOM 2211 C C   . ALA B 2 36  ? 139.780 108.832 175.459 1.00 138.07 ? 26  ALA B C   1 
ATOM 2212 O O   . ALA B 2 36  ? 140.569 109.778 175.467 1.00 139.52 ? 26  ALA B O   1 
ATOM 2213 C CB  . ALA B 2 36  ? 137.975 110.377 174.601 1.00 123.82 ? 26  ALA B CB  1 
ATOM 2214 N N   . ASP B 2 37  ? 140.160 107.573 175.691 1.00 141.40 ? 27  ASP B N   1 
ATOM 2215 C CA  . ASP B 2 37  ? 141.558 107.269 175.978 1.00 140.86 ? 27  ASP B CA  1 
ATOM 2216 C C   . ASP B 2 37  ? 142.420 107.352 174.726 1.00 140.58 ? 27  ASP B C   1 
ATOM 2217 O O   . ASP B 2 37  ? 143.614 107.659 174.818 1.00 144.36 ? 27  ASP B O   1 
ATOM 2218 C CB  . ASP B 2 37  ? 141.676 105.887 176.623 1.00 140.71 ? 27  ASP B CB  1 
ATOM 2219 C CG  . ASP B 2 37  ? 141.439 104.758 175.638 1.00 144.67 ? 27  ASP B CG  1 
ATOM 2220 O OD1 . ASP B 2 37  ? 140.509 104.871 174.812 1.00 143.87 ? 27  ASP B OD1 1 
ATOM 2221 O OD2 . ASP B 2 37  ? 142.183 103.756 175.690 1.00 145.88 ? 27  ASP B OD2 1 
ATOM 2222 N N   . ALA B 2 38  ? 141.837 107.094 173.558 1.00 136.49 ? 28  ALA B N   1 
ATOM 2223 C CA  . ALA B 2 38  ? 142.563 107.140 172.298 1.00 131.70 ? 28  ALA B CA  1 
ATOM 2224 C C   . ALA B 2 38  ? 141.555 107.325 171.176 1.00 131.77 ? 28  ALA B C   1 
ATOM 2225 O O   . ALA B 2 38  ? 140.343 107.252 171.384 1.00 134.24 ? 28  ALA B O   1 
ATOM 2226 C CB  . ALA B 2 38  ? 143.397 105.873 172.081 1.00 121.58 ? 28  ALA B CB  1 
ATOM 2227 N N   . THR B 2 39  ? 142.074 107.583 169.981 1.00 126.46 ? 29  THR B N   1 
ATOM 2228 C CA  . THR B 2 39  ? 141.270 107.634 168.772 1.00 122.28 ? 29  THR B CA  1 
ATOM 2229 C C   . THR B 2 39  ? 141.697 106.515 167.835 1.00 118.84 ? 29  THR B C   1 
ATOM 2230 O O   . THR B 2 39  ? 142.783 105.947 167.964 1.00 120.03 ? 29  THR B O   1 
ATOM 2231 C CB  . THR B 2 39  ? 141.399 108.989 168.067 1.00 121.76 ? 29  THR B CB  1 
ATOM 2232 O OG1 . THR B 2 39  ? 142.711 109.117 167.507 1.00 127.05 ? 29  THR B OG1 1 
ATOM 2233 C CG2 . THR B 2 39  ? 141.155 110.129 169.044 1.00 118.81 ? 29  THR B CG2 1 
ATOM 2234 N N   . LEU B 2 40  ? 140.823 106.196 166.885 1.00 115.73 ? 30  LEU B N   1 
ATOM 2235 C CA  . LEU B 2 40  ? 141.094 105.114 165.948 1.00 115.99 ? 30  LEU B CA  1 
ATOM 2236 C C   . LEU B 2 40  ? 142.008 105.534 164.807 1.00 114.47 ? 30  LEU B C   1 
ATOM 2237 O O   . LEU B 2 40  ? 142.383 104.681 163.992 1.00 120.90 ? 30  LEU B O   1 
ATOM 2238 C CB  . LEU B 2 40  ? 139.786 104.551 165.385 1.00 118.36 ? 30  LEU B CB  1 
ATOM 2239 C CG  . LEU B 2 40  ? 139.135 105.281 164.214 1.00 115.45 ? 30  LEU B CG  1 
ATOM 2240 C CD1 . LEU B 2 40  ? 138.300 104.322 163.383 1.00 108.51 ? 30  LEU B CD1 1 
ATOM 2241 C CD2 . LEU B 2 40  ? 138.277 106.401 164.734 1.00 110.79 ? 30  LEU B CD2 1 
ATOM 2242 N N   . SER B 2 41  ? 142.373 106.816 164.736 1.00 109.61 ? 31  SER B N   1 
ATOM 2243 C CA  . SER B 2 41  ? 143.315 107.271 163.719 1.00 112.83 ? 31  SER B CA  1 
ATOM 2244 C C   . SER B 2 41  ? 144.691 106.645 163.915 1.00 117.96 ? 31  SER B C   1 
ATOM 2245 O O   . SER B 2 41  ? 145.413 106.401 162.940 1.00 120.49 ? 31  SER B O   1 
ATOM 2246 C CB  . SER B 2 41  ? 143.410 108.794 163.743 1.00 112.18 ? 31  SER B CB  1 
ATOM 2247 O OG  . SER B 2 41  ? 143.808 109.256 165.021 1.00 116.92 ? 31  SER B OG  1 
ATOM 2248 N N   . GLN B 2 42  ? 145.074 106.376 165.161 1.00 117.00 ? 32  GLN B N   1 
ATOM 2249 C CA  . GLN B 2 42  ? 146.345 105.723 165.442 1.00 114.66 ? 32  GLN B CA  1 
ATOM 2250 C C   . GLN B 2 42  ? 146.224 104.211 165.574 1.00 109.75 ? 32  GLN B C   1 
ATOM 2251 O O   . GLN B 2 42  ? 147.221 103.553 165.885 1.00 112.11 ? 32  GLN B O   1 
ATOM 2252 C CB  . GLN B 2 42  ? 146.979 106.295 166.714 1.00 116.94 ? 32  GLN B CB  1 
ATOM 2253 C CG  . GLN B 2 42  ? 146.070 106.322 167.927 1.00 118.40 ? 32  GLN B CG  1 
ATOM 2254 C CD  . GLN B 2 42  ? 145.411 107.671 168.127 1.00 122.23 ? 32  GLN B CD  1 
ATOM 2255 O OE1 . GLN B 2 42  ? 144.820 108.227 167.202 1.00 125.79 ? 32  GLN B OE1 1 
ATOM 2256 N NE2 . GLN B 2 42  ? 145.510 108.206 169.338 1.00 117.56 ? 32  GLN B NE2 1 
ATOM 2257 N N   . ILE B 2 43  ? 145.041 103.643 165.353 1.00 108.59 ? 33  ILE B N   1 
ATOM 2258 C CA  . ILE B 2 43  ? 144.868 102.200 165.438 1.00 110.66 ? 33  ILE B CA  1 
ATOM 2259 C C   . ILE B 2 43  ? 144.407 101.574 164.128 1.00 107.23 ? 33  ILE B C   1 
ATOM 2260 O O   . ILE B 2 43  ? 144.513 100.345 163.976 1.00 105.87 ? 33  ILE B O   1 
ATOM 2261 C CB  . ILE B 2 43  ? 143.905 101.820 166.588 1.00 113.15 ? 33  ILE B CB  1 
ATOM 2262 C CG1 . ILE B 2 43  ? 144.364 100.529 167.268 1.00 113.47 ? 33  ILE B CG1 1 
ATOM 2263 C CG2 . ILE B 2 43  ? 142.465 101.686 166.107 1.00 111.03 ? 33  ILE B CG2 1 
ATOM 2264 C CD1 . ILE B 2 43  ? 143.732 100.295 168.622 1.00 104.54 ? 33  ILE B CD1 1 
ATOM 2265 N N   . THR B 2 44  ? 143.929 102.353 163.162 1.00 109.41 ? 34  THR B N   1 
ATOM 2266 C CA  . THR B 2 44  ? 143.472 101.806 161.893 1.00 113.25 ? 34  THR B CA  1 
ATOM 2267 C C   . THR B 2 44  ? 144.525 101.870 160.795 1.00 115.05 ? 34  THR B C   1 
ATOM 2268 O O   . THR B 2 44  ? 144.251 101.438 159.671 1.00 115.32 ? 34  THR B O   1 
ATOM 2269 C CB  . THR B 2 44  ? 142.209 102.532 161.430 1.00 115.07 ? 34  THR B CB  1 
ATOM 2270 O OG1 . THR B 2 44  ? 142.367 103.942 161.631 1.00 116.41 ? 34  THR B OG1 1 
ATOM 2271 C CG2 . THR B 2 44  ? 141.004 102.041 162.212 1.00 112.09 ? 34  THR B CG2 1 
ATOM 2272 N N   . ASN B 2 45  ? 145.716 102.391 161.086 1.00 113.67 ? 35  ASN B N   1 
ATOM 2273 C CA  . ASN B 2 45  ? 146.763 102.485 160.077 1.00 110.03 ? 35  ASN B CA  1 
ATOM 2274 C C   . ASN B 2 45  ? 147.481 101.165 159.834 1.00 107.59 ? 35  ASN B C   1 
ATOM 2275 O O   . ASN B 2 45  ? 148.221 101.055 158.851 1.00 105.50 ? 35  ASN B O   1 
ATOM 2276 C CB  . ASN B 2 45  ? 147.785 103.548 160.481 1.00 104.77 ? 35  ASN B CB  1 
ATOM 2277 C CG  . ASN B 2 45  ? 148.501 103.207 161.770 1.00 102.76 ? 35  ASN B CG  1 
ATOM 2278 O OD1 . ASN B 2 45  ? 147.982 102.469 162.606 1.00 101.73 ? 35  ASN B OD1 1 
ATOM 2279 N ND2 . ASN B 2 45  ? 149.701 103.745 161.938 1.00 104.69 ? 35  ASN B ND2 1 
ATOM 2280 N N   . ASN B 2 46  ? 147.287 100.170 160.702 1.00 107.14 ? 36  ASN B N   1 
ATOM 2281 C CA  . ASN B 2 46  ? 148.043 98.929  160.587 1.00 102.56 ? 36  ASN B CA  1 
ATOM 2282 C C   . ASN B 2 46  ? 147.565 98.089  159.410 1.00 108.51 ? 36  ASN B C   1 
ATOM 2283 O O   . ASN B 2 46  ? 148.382 97.514  158.681 1.00 113.32 ? 36  ASN B O   1 
ATOM 2284 C CB  . ASN B 2 46  ? 147.947 98.142  161.890 1.00 98.70  ? 36  ASN B CB  1 
ATOM 2285 C CG  . ASN B 2 46  ? 148.765 98.764  163.000 1.00 97.85  ? 36  ASN B CG  1 
ATOM 2286 O OD1 . ASN B 2 46  ? 149.321 99.851  162.840 1.00 93.56  ? 36  ASN B OD1 1 
ATOM 2287 N ND2 . ASN B 2 46  ? 148.843 98.079  164.135 1.00 104.91 ? 36  ASN B ND2 1 
ATOM 2288 N N   . ILE B 2 47  ? 146.251 97.999  159.211 1.00 107.00 ? 37  ILE B N   1 
ATOM 2289 C CA  . ILE B 2 47  ? 145.717 97.272  158.067 1.00 107.02 ? 37  ILE B CA  1 
ATOM 2290 C C   . ILE B 2 47  ? 145.972 98.086  156.806 1.00 100.77 ? 37  ILE B C   1 
ATOM 2291 O O   . ILE B 2 47  ? 145.726 99.299  156.775 1.00 98.90  ? 37  ILE B O   1 
ATOM 2292 C CB  . ILE B 2 47  ? 144.225 96.963  158.274 1.00 109.97 ? 37  ILE B CB  1 
ATOM 2293 C CG1 . ILE B 2 47  ? 144.069 95.680  159.096 1.00 108.84 ? 37  ILE B CG1 1 
ATOM 2294 C CG2 . ILE B 2 47  ? 143.480 96.833  156.947 1.00 105.99 ? 37  ILE B CG2 1 
ATOM 2295 C CD1 . ILE B 2 47  ? 142.633 95.257  159.323 1.00 103.23 ? 37  ILE B CD1 1 
ATOM 2296 N N   . ASP B 2 48  ? 146.510 97.426  155.781 1.00 99.80  ? 38  ASP B N   1 
ATOM 2297 C CA  . ASP B 2 48  ? 146.901 98.108  154.557 1.00 100.40 ? 38  ASP B CA  1 
ATOM 2298 C C   . ASP B 2 48  ? 145.672 98.675  153.852 1.00 98.72  ? 38  ASP B C   1 
ATOM 2299 O O   . ASP B 2 48  ? 144.604 98.054  153.875 1.00 100.60 ? 38  ASP B O   1 
ATOM 2300 C CB  . ASP B 2 48  ? 147.643 97.146  153.627 1.00 106.29 ? 38  ASP B CB  1 
ATOM 2301 C CG  . ASP B 2 48  ? 146.951 95.803  153.503 1.00 115.75 ? 38  ASP B CG  1 
ATOM 2302 O OD1 . ASP B 2 48  ? 146.094 95.493  154.357 1.00 118.39 ? 38  ASP B OD1 1 
ATOM 2303 O OD2 . ASP B 2 48  ? 147.263 95.058  152.551 1.00 118.26 ? 38  ASP B OD2 1 
ATOM 2304 N N   . PRO B 2 49  ? 145.779 99.853  153.242 1.00 97.27  ? 39  PRO B N   1 
ATOM 2305 C CA  . PRO B 2 49  ? 144.608 100.472 152.619 1.00 95.62  ? 39  PRO B CA  1 
ATOM 2306 C C   . PRO B 2 49  ? 144.167 99.718  151.377 1.00 92.88  ? 39  PRO B C   1 
ATOM 2307 O O   . PRO B 2 49  ? 144.921 98.955  150.770 1.00 94.87  ? 39  PRO B O   1 
ATOM 2308 C CB  . PRO B 2 49  ? 145.094 101.880 152.268 1.00 92.85  ? 39  PRO B CB  1 
ATOM 2309 C CG  . PRO B 2 49  ? 146.557 101.729 152.094 1.00 93.78  ? 39  PRO B CG  1 
ATOM 2310 C CD  . PRO B 2 49  ? 146.985 100.686 153.087 1.00 97.02  ? 39  PRO B CD  1 
ATOM 2311 N N   . VAL B 2 50  ? 142.904 99.942  151.010 1.00 87.76  ? 40  VAL B N   1 
ATOM 2312 C CA  . VAL B 2 50  ? 142.318 99.265  149.861 1.00 94.04  ? 40  VAL B CA  1 
ATOM 2313 C C   . VAL B 2 50  ? 142.865 99.786  148.540 1.00 98.17  ? 40  VAL B C   1 
ATOM 2314 O O   . VAL B 2 50  ? 142.727 99.116  147.511 1.00 100.08 ? 40  VAL B O   1 
ATOM 2315 C CB  . VAL B 2 50  ? 140.781 99.392  149.951 1.00 101.03 ? 40  VAL B CB  1 
ATOM 2316 C CG1 . VAL B 2 50  ? 140.327 100.784 149.568 1.00 100.64 ? 40  VAL B CG1 1 
ATOM 2317 C CG2 . VAL B 2 50  ? 140.078 98.318  149.125 1.00 99.93  ? 40  VAL B CG2 1 
ATOM 2318 N N   . GLY B 2 51  ? 143.520 100.942 148.545 1.00 100.74 ? 41  GLY B N   1 
ATOM 2319 C CA  . GLY B 2 51  ? 144.071 101.484 147.324 1.00 102.59 ? 41  GLY B CA  1 
ATOM 2320 C C   . GLY B 2 51  ? 142.998 102.102 146.447 1.00 99.73  ? 41  GLY B C   1 
ATOM 2321 O O   . GLY B 2 51  ? 141.899 102.444 146.896 1.00 99.52  ? 41  GLY B O   1 
ATOM 2322 N N   . ARG B 2 52  ? 143.337 102.252 145.171 1.00 93.46  ? 42  ARG B N   1 
ATOM 2323 C CA  . ARG B 2 52  ? 142.400 102.826 144.216 1.00 86.77  ? 42  ARG B CA  1 
ATOM 2324 C C   . ARG B 2 52  ? 141.278 101.839 143.930 1.00 90.43  ? 42  ARG B C   1 
ATOM 2325 O O   . ARG B 2 52  ? 141.525 100.662 143.655 1.00 88.78  ? 42  ARG B O   1 
ATOM 2326 C CB  . ARG B 2 52  ? 143.120 103.201 142.922 1.00 83.03  ? 42  ARG B CB  1 
ATOM 2327 N N   . ILE B 2 53  ? 140.042 102.321 144.010 1.00 98.27  ? 43  ILE B N   1 
ATOM 2328 C CA  . ILE B 2 53  ? 138.857 101.532 143.704 1.00 92.37  ? 43  ILE B CA  1 
ATOM 2329 C C   . ILE B 2 53  ? 138.114 102.237 142.584 1.00 88.04  ? 43  ILE B C   1 
ATOM 2330 O O   . ILE B 2 53  ? 137.617 103.354 142.769 1.00 91.03  ? 43  ILE B O   1 
ATOM 2331 C CB  . ILE B 2 53  ? 137.954 101.351 144.932 1.00 87.73  ? 43  ILE B CB  1 
ATOM 2332 C CG1 . ILE B 2 53  ? 138.693 100.579 146.024 1.00 90.54  ? 43  ILE B CG1 1 
ATOM 2333 C CG2 . ILE B 2 53  ? 136.677 100.634 144.547 1.00 86.15  ? 43  ILE B CG2 1 
ATOM 2334 C CD1 . ILE B 2 53  ? 139.119 99.191  145.600 1.00 91.68  ? 43  ILE B CD1 1 
ATOM 2335 N N   . GLN B 2 54  ? 138.038 101.589 141.427 1.00 81.74  ? 44  GLN B N   1 
ATOM 2336 C CA  . GLN B 2 54  ? 137.399 102.164 140.255 1.00 87.90  ? 44  GLN B CA  1 
ATOM 2337 C C   . GLN B 2 54  ? 136.330 101.207 139.761 1.00 86.77  ? 44  GLN B C   1 
ATOM 2338 O O   . GLN B 2 54  ? 136.595 100.015 139.580 1.00 89.92  ? 44  GLN B O   1 
ATOM 2339 C CB  . GLN B 2 54  ? 138.420 102.442 139.148 1.00 97.88  ? 44  GLN B CB  1 
ATOM 2340 C CG  . GLN B 2 54  ? 137.890 103.315 138.024 1.00 104.72 ? 44  GLN B CG  1 
ATOM 2341 C CD  . GLN B 2 54  ? 138.971 103.724 137.045 1.00 120.39 ? 44  GLN B CD  1 
ATOM 2342 O OE1 . GLN B 2 54  ? 140.151 103.441 137.252 1.00 122.97 ? 44  GLN B OE1 1 
ATOM 2343 N NE2 . GLN B 2 54  ? 138.573 104.395 135.970 1.00 124.04 ? 44  GLN B NE2 1 
ATOM 2344 N N   . MET B 2 55  ? 135.126 101.729 139.547 1.00 85.11  ? 45  MET B N   1 
ATOM 2345 C CA  . MET B 2 55  ? 134.015 100.931 139.060 1.00 83.80  ? 45  MET B CA  1 
ATOM 2346 C C   . MET B 2 55  ? 133.303 101.693 137.954 1.00 82.58  ? 45  MET B C   1 
ATOM 2347 O O   . MET B 2 55  ? 133.275 102.925 137.945 1.00 86.18  ? 45  MET B O   1 
ATOM 2348 C CB  . MET B 2 55  ? 133.052 100.574 140.195 1.00 82.27  ? 45  MET B CB  1 
ATOM 2349 C CG  . MET B 2 55  ? 133.113 101.527 141.369 1.00 85.79  ? 45  MET B CG  1 
ATOM 2350 S SD  . MET B 2 55  ? 132.263 100.880 142.816 1.00 100.36 ? 45  MET B SD  1 
ATOM 2351 C CE  . MET B 2 55  ? 133.305 99.476  143.195 1.00 91.62  ? 45  MET B CE  1 
ATOM 2352 N N   . ARG B 2 56  ? 132.726 100.943 137.023 1.00 79.65  ? 46  ARG B N   1 
ATOM 2353 C CA  . ARG B 2 56  ? 132.189 101.480 135.785 1.00 82.06  ? 46  ARG B CA  1 
ATOM 2354 C C   . ARG B 2 56  ? 130.682 101.261 135.756 1.00 79.11  ? 46  ARG B C   1 
ATOM 2355 O O   . ARG B 2 56  ? 130.176 100.300 136.341 1.00 79.90  ? 46  ARG B O   1 
ATOM 2356 C CB  . ARG B 2 56  ? 132.897 100.811 134.579 1.00 95.18  ? 46  ARG B CB  1 
ATOM 2357 C CG  . ARG B 2 56  ? 132.140 100.751 133.253 1.00 102.85 ? 46  ARG B CG  1 
ATOM 2358 C CD  . ARG B 2 56  ? 132.825 99.836  132.247 1.00 114.97 ? 46  ARG B CD  1 
ATOM 2359 N NE  . ARG B 2 56  ? 134.274 99.997  132.245 1.00 133.15 ? 46  ARG B NE  1 
ATOM 2360 C CZ  . ARG B 2 56  ? 135.138 99.024  132.503 1.00 132.16 ? 46  ARG B CZ  1 
ATOM 2361 N NH1 . ARG B 2 56  ? 134.732 97.798  132.790 1.00 127.38 ? 46  ARG B NH1 1 
ATOM 2362 N NH2 . ARG B 2 56  ? 136.441 99.288  132.471 1.00 125.60 ? 46  ARG B NH2 1 
ATOM 2363 N N   . THR B 2 57  ? 129.963 102.188 135.115 1.00 78.13  ? 47  THR B N   1 
ATOM 2364 C CA  . THR B 2 57  ? 128.526 102.044 134.916 1.00 77.34  ? 47  THR B CA  1 
ATOM 2365 C C   . THR B 2 57  ? 128.217 100.789 134.114 1.00 78.20  ? 47  THR B C   1 
ATOM 2366 O O   . THR B 2 57  ? 128.524 100.713 132.920 1.00 89.57  ? 47  THR B O   1 
ATOM 2367 C CB  . THR B 2 57  ? 127.948 103.262 134.194 1.00 82.87  ? 47  THR B CB  1 
ATOM 2368 O OG1 . THR B 2 57  ? 128.154 104.436 134.986 1.00 84.86  ? 47  THR B OG1 1 
ATOM 2369 C CG2 . THR B 2 57  ? 126.458 103.080 133.953 1.00 78.54  ? 47  THR B CG2 1 
ATOM 2370 N N   . ARG B 2 58  ? 127.620 99.795  134.768 1.00 71.46  ? 48  ARG B N   1 
ATOM 2371 C CA  . ARG B 2 58  ? 127.280 98.559  134.078 1.00 73.55  ? 48  ARG B CA  1 
ATOM 2372 C C   . ARG B 2 58  ? 125.963 98.705  133.328 1.00 73.36  ? 48  ARG B C   1 
ATOM 2373 O O   . ARG B 2 58  ? 125.904 98.514  132.108 1.00 76.19  ? 48  ARG B O   1 
ATOM 2374 C CB  . ARG B 2 58  ? 127.215 97.404  135.077 1.00 72.10  ? 48  ARG B CB  1 
ATOM 2375 C CG  . ARG B 2 58  ? 128.511 97.173  135.829 1.00 72.42  ? 48  ARG B CG  1 
ATOM 2376 C CD  . ARG B 2 58  ? 129.600 96.683  134.899 1.00 78.04  ? 48  ARG B CD  1 
ATOM 2377 N NE  . ARG B 2 58  ? 130.833 96.376  135.613 1.00 89.83  ? 48  ARG B NE  1 
ATOM 2378 C CZ  . ARG B 2 58  ? 131.480 95.222  135.529 1.00 100.00 ? 48  ARG B CZ  1 
ATOM 2379 N NH1 . ARG B 2 58  ? 131.035 94.233  134.771 1.00 93.62  ? 48  ARG B NH1 1 
ATOM 2380 N NH2 . ARG B 2 58  ? 132.603 95.055  136.222 1.00 103.97 ? 48  ARG B NH2 1 
ATOM 2381 N N   . ARG B 2 59  ? 124.896 99.043  134.043 1.00 68.93  ? 49  ARG B N   1 
ATOM 2382 C CA  . ARG B 2 59  ? 123.594 99.306  133.452 1.00 65.62  ? 49  ARG B CA  1 
ATOM 2383 C C   . ARG B 2 59  ? 123.108 100.688 133.845 1.00 66.94  ? 49  ARG B C   1 
ATOM 2384 O O   . ARG B 2 59  ? 123.294 101.125 134.984 1.00 76.59  ? 49  ARG B O   1 
ATOM 2385 C CB  . ARG B 2 59  ? 122.563 98.264  133.870 1.00 66.09  ? 49  ARG B CB  1 
ATOM 2386 C CG  . ARG B 2 59  ? 123.088 96.859  133.867 1.00 73.45  ? 49  ARG B CG  1 
ATOM 2387 C CD  . ARG B 2 59  ? 121.938 95.870  133.804 1.00 77.15  ? 49  ARG B CD  1 
ATOM 2388 N NE  . ARG B 2 59  ? 122.202 94.649  133.045 1.00 74.83  ? 49  ARG B NE  1 
ATOM 2389 C CZ  . ARG B 2 59  ? 123.170 93.770  133.273 1.00 81.14  ? 49  ARG B CZ  1 
ATOM 2390 N NH1 . ARG B 2 59  ? 123.943 93.842  134.342 1.00 71.19  ? 49  ARG B NH1 1 
ATOM 2391 N NH2 . ARG B 2 59  ? 123.339 92.761  132.423 1.00 93.36  ? 49  ARG B NH2 1 
ATOM 2392 N N   . THR B 2 60  ? 122.483 101.368 132.892 1.00 62.87  ? 50  THR B N   1 
ATOM 2393 C CA  . THR B 2 60  ? 121.881 102.676 133.110 1.00 72.95  ? 50  THR B CA  1 
ATOM 2394 C C   . THR B 2 60  ? 120.389 102.572 132.791 1.00 82.16  ? 50  THR B C   1 
ATOM 2395 O O   . THR B 2 60  ? 119.963 102.462 131.639 1.00 87.75  ? 50  THR B O   1 
ATOM 2396 C CB  . THR B 2 60  ? 122.637 103.789 132.302 1.00 80.71  ? 50  THR B CB  1 
ATOM 2397 O OG1 . THR B 2 60  ? 122.040 105.071 132.542 1.00 85.62  ? 50  THR B OG1 1 
ATOM 2398 C CG2 . THR B 2 60  ? 122.785 103.488 130.800 1.00 83.37  ? 50  THR B CG2 1 
ATOM 2399 N N   . LEU B 2 61  ? 119.582 102.553 133.845 1.00 80.49  ? 51  LEU B N   1 
ATOM 2400 C CA  . LEU B 2 61  ? 118.143 102.429 133.679 1.00 79.87  ? 51  LEU B CA  1 
ATOM 2401 C C   . LEU B 2 61  ? 117.556 103.778 133.293 1.00 83.33  ? 51  LEU B C   1 
ATOM 2402 O O   . LEU B 2 61  ? 117.622 104.738 134.066 1.00 85.14  ? 51  LEU B O   1 
ATOM 2403 C CB  . LEU B 2 61  ? 117.509 101.903 134.960 1.00 76.33  ? 51  LEU B CB  1 
ATOM 2404 C CG  . LEU B 2 61  ? 118.309 100.812 135.666 1.00 79.91  ? 51  LEU B CG  1 
ATOM 2405 C CD1 . LEU B 2 61  ? 117.895 100.700 137.120 1.00 81.57  ? 51  LEU B CD1 1 
ATOM 2406 C CD2 . LEU B 2 61  ? 118.154 99.480  134.957 1.00 79.99  ? 51  LEU B CD2 1 
ATOM 2407 N N   . ARG B 2 62  ? 116.991 103.849 132.096 1.00 84.01  ? 52  ARG B N   1 
ATOM 2408 C CA  . ARG B 2 62  ? 116.399 105.060 131.558 1.00 81.01  ? 52  ARG B CA  1 
ATOM 2409 C C   . ARG B 2 62  ? 114.891 104.887 131.448 1.00 86.65  ? 52  ARG B C   1 
ATOM 2410 O O   . ARG B 2 62  ? 114.388 103.792 131.186 1.00 94.02  ? 52  ARG B O   1 
ATOM 2411 C CB  . ARG B 2 62  ? 116.989 105.387 130.182 1.00 86.48  ? 52  ARG B CB  1 
ATOM 2412 C CG  . ARG B 2 62  ? 118.500 105.551 130.173 1.00 91.78  ? 52  ARG B CG  1 
ATOM 2413 C CD  . ARG B 2 62  ? 119.154 104.836 128.998 1.00 100.22 ? 52  ARG B CD  1 
ATOM 2414 N NE  . ARG B 2 62  ? 118.768 103.433 128.915 1.00 106.96 ? 52  ARG B NE  1 
ATOM 2415 C CZ  . ARG B 2 62  ? 119.107 102.621 127.922 1.00 113.13 ? 52  ARG B CZ  1 
ATOM 2416 N NH1 . ARG B 2 62  ? 119.844 103.041 126.907 1.00 112.48 ? 52  ARG B NH1 1 
ATOM 2417 N NH2 . ARG B 2 62  ? 118.699 101.355 127.951 1.00 115.11 ? 52  ARG B NH2 1 
ATOM 2418 N N   . GLY B 2 63  ? 114.168 105.986 131.629 1.00 84.88  ? 53  GLY B N   1 
ATOM 2419 C CA  . GLY B 2 63  ? 112.726 105.931 131.514 1.00 84.93  ? 53  GLY B CA  1 
ATOM 2420 C C   . GLY B 2 63  ? 111.970 106.861 132.438 1.00 80.72  ? 53  GLY B C   1 
ATOM 2421 O O   . GLY B 2 63  ? 110.777 107.099 132.238 1.00 84.45  ? 53  GLY B O   1 
ATOM 2422 N N   . HIS B 2 64  ? 112.640 107.394 133.451 1.00 76.77  ? 54  HIS B N   1 
ATOM 2423 C CA  . HIS B 2 64  ? 112.022 108.408 134.288 1.00 77.29  ? 54  HIS B CA  1 
ATOM 2424 C C   . HIS B 2 64  ? 112.124 109.769 133.614 1.00 79.22  ? 54  HIS B C   1 
ATOM 2425 O O   . HIS B 2 64  ? 112.970 109.992 132.743 1.00 82.65  ? 54  HIS B O   1 
ATOM 2426 C CB  . HIS B 2 64  ? 112.676 108.437 135.667 1.00 76.57  ? 54  HIS B CB  1 
ATOM 2427 C CG  . HIS B 2 64  ? 112.061 107.483 136.643 1.00 82.44  ? 54  HIS B CG  1 
ATOM 2428 N ND1 . HIS B 2 64  ? 110.748 107.580 137.050 1.00 87.04  ? 54  HIS B ND1 1 
ATOM 2429 C CD2 . HIS B 2 64  ? 112.568 106.397 137.269 1.00 78.21  ? 54  HIS B CD2 1 
ATOM 2430 C CE1 . HIS B 2 64  ? 110.481 106.606 137.902 1.00 81.24  ? 54  HIS B CE1 1 
ATOM 2431 N NE2 . HIS B 2 64  ? 111.570 105.875 138.053 1.00 76.78  ? 54  HIS B NE2 1 
ATOM 2432 N N   . LEU B 2 65  ? 111.235 110.680 134.006 1.00 77.37  ? 55  LEU B N   1 
ATOM 2433 C CA  . LEU B 2 65  ? 111.154 111.995 133.383 1.00 71.50  ? 55  LEU B CA  1 
ATOM 2434 C C   . LEU B 2 65  ? 111.715 113.099 134.268 1.00 75.95  ? 55  LEU B C   1 
ATOM 2435 O O   . LEU B 2 65  ? 112.625 113.821 133.856 1.00 79.31  ? 55  LEU B O   1 
ATOM 2436 C CB  . LEU B 2 65  ? 109.705 112.319 133.011 1.00 66.57  ? 55  LEU B CB  1 
ATOM 2437 C CG  . LEU B 2 65  ? 109.064 111.605 131.826 1.00 77.18  ? 55  LEU B CG  1 
ATOM 2438 C CD1 . LEU B 2 65  ? 108.454 110.265 132.212 1.00 79.85  ? 55  LEU B CD1 1 
ATOM 2439 C CD2 . LEU B 2 65  ? 108.026 112.520 131.230 1.00 84.59  ? 55  LEU B CD2 1 
ATOM 2440 N N   . ALA B 2 66  ? 111.194 113.250 135.477 1.00 73.93  ? 56  ALA B N   1 
ATOM 2441 C CA  . ALA B 2 66  ? 111.607 114.327 136.359 1.00 72.92  ? 56  ALA B CA  1 
ATOM 2442 C C   . ALA B 2 66  ? 112.797 113.868 137.193 1.00 71.78  ? 56  ALA B C   1 
ATOM 2443 O O   . ALA B 2 66  ? 113.403 112.829 136.928 1.00 75.42  ? 56  ALA B O   1 
ATOM 2444 C CB  . ALA B 2 66  ? 110.437 114.779 137.229 1.00 75.48  ? 56  ALA B CB  1 
ATOM 2445 N N   . LYS B 2 67  ? 113.145 114.648 138.210 1.00 71.51  ? 57  LYS B N   1 
ATOM 2446 C CA  . LYS B 2 67  ? 114.242 114.285 139.092 1.00 69.66  ? 57  LYS B CA  1 
ATOM 2447 C C   . LYS B 2 67  ? 113.886 113.054 139.909 1.00 72.37  ? 57  LYS B C   1 
ATOM 2448 O O   . LYS B 2 67  ? 112.740 112.872 140.326 1.00 80.40  ? 57  LYS B O   1 
ATOM 2449 C CB  . LYS B 2 67  ? 114.578 115.440 140.028 1.00 76.92  ? 57  LYS B CB  1 
ATOM 2450 C CG  . LYS B 2 67  ? 114.099 116.787 139.551 1.00 81.78  ? 57  LYS B CG  1 
ATOM 2451 C CD  . LYS B 2 67  ? 114.588 117.874 140.478 1.00 81.78  ? 57  LYS B CD  1 
ATOM 2452 C CE  . LYS B 2 67  ? 113.984 117.721 141.859 1.00 80.80  ? 57  LYS B CE  1 
ATOM 2453 N NZ  . LYS B 2 67  ? 112.501 117.754 141.809 1.00 82.72  ? 57  LYS B NZ  1 
ATOM 2454 N N   . ILE B 2 68  ? 114.877 112.206 140.136 1.00 69.53  ? 58  ILE B N   1 
ATOM 2455 C CA  . ILE B 2 68  ? 114.701 110.970 140.880 1.00 68.16  ? 58  ILE B CA  1 
ATOM 2456 C C   . ILE B 2 68  ? 115.180 111.250 142.295 1.00 72.20  ? 58  ILE B C   1 
ATOM 2457 O O   . ILE B 2 68  ? 116.322 111.680 142.497 1.00 83.93  ? 58  ILE B O   1 
ATOM 2458 C CB  . ILE B 2 68  ? 115.475 109.820 140.222 1.00 69.38  ? 58  ILE B CB  1 
ATOM 2459 C CG1 . ILE B 2 68  ? 114.607 109.183 139.147 1.00 75.07  ? 58  ILE B CG1 1 
ATOM 2460 C CG2 . ILE B 2 68  ? 115.830 108.751 141.233 1.00 72.39  ? 58  ILE B CG2 1 
ATOM 2461 C CD1 . ILE B 2 68  ? 115.316 108.143 138.353 1.00 80.78  ? 58  ILE B CD1 1 
ATOM 2462 N N   . TYR B 2 69  ? 114.303 111.058 143.274 1.00 66.93  ? 59  TYR B N   1 
ATOM 2463 C CA  . TYR B 2 69  ? 114.598 111.517 144.622 1.00 69.84  ? 59  TYR B CA  1 
ATOM 2464 C C   . TYR B 2 69  ? 115.067 110.402 145.541 1.00 72.01  ? 59  TYR B C   1 
ATOM 2465 O O   . TYR B 2 69  ? 115.993 110.609 146.330 1.00 79.90  ? 59  TYR B O   1 
ATOM 2466 C CB  . TYR B 2 69  ? 113.371 112.191 145.233 1.00 74.23  ? 59  TYR B CB  1 
ATOM 2467 C CG  . TYR B 2 69  ? 113.687 113.485 145.940 1.00 80.74  ? 59  TYR B CG  1 
ATOM 2468 C CD1 . TYR B 2 69  ? 113.520 114.703 145.298 1.00 80.61  ? 59  TYR B CD1 1 
ATOM 2469 C CD2 . TYR B 2 69  ? 114.186 113.489 147.232 1.00 87.83  ? 59  TYR B CD2 1 
ATOM 2470 C CE1 . TYR B 2 69  ? 113.811 115.890 145.933 1.00 89.64  ? 59  TYR B CE1 1 
ATOM 2471 C CE2 . TYR B 2 69  ? 114.483 114.672 147.878 1.00 96.24  ? 59  TYR B CE2 1 
ATOM 2472 C CZ  . TYR B 2 69  ? 114.295 115.870 147.222 1.00 99.60  ? 59  TYR B CZ  1 
ATOM 2473 O OH  . TYR B 2 69  ? 114.592 117.052 147.860 1.00 108.15 ? 59  TYR B OH  1 
ATOM 2474 N N   . ALA B 2 70  ? 114.457 109.225 145.462 1.00 65.78  ? 60  ALA B N   1 
ATOM 2475 C CA  . ALA B 2 70  ? 114.835 108.121 146.327 1.00 68.42  ? 60  ALA B CA  1 
ATOM 2476 C C   . ALA B 2 70  ? 114.721 106.810 145.571 1.00 69.08  ? 60  ALA B C   1 
ATOM 2477 O O   . ALA B 2 70  ? 113.869 106.669 144.690 1.00 75.60  ? 60  ALA B O   1 
ATOM 2478 C CB  . ALA B 2 70  ? 113.960 108.075 147.583 1.00 69.91  ? 60  ALA B CB  1 
ATOM 2479 N N   . MET B 2 71  ? 115.587 105.857 145.907 1.00 64.81  ? 61  MET B N   1 
ATOM 2480 C CA  . MET B 2 71  ? 115.382 104.476 145.512 1.00 59.02  ? 61  MET B CA  1 
ATOM 2481 C C   . MET B 2 71  ? 115.637 103.559 146.695 1.00 59.98  ? 61  MET B C   1 
ATOM 2482 O O   . MET B 2 71  ? 116.193 103.959 147.720 1.00 68.98  ? 61  MET B O   1 
ATOM 2483 C CB  . MET B 2 71  ? 116.274 104.017 144.356 1.00 61.48  ? 61  MET B CB  1 
ATOM 2484 C CG  . MET B 2 71  ? 117.722 103.785 144.705 1.00 70.35  ? 61  MET B CG  1 
ATOM 2485 S SD  . MET B 2 71  ? 118.790 104.411 143.409 1.00 102.03 ? 61  MET B SD  1 
ATOM 2486 C CE  . MET B 2 71  ? 118.423 103.184 142.161 1.00 91.12  ? 61  MET B CE  1 
ATOM 2487 N N   . HIS B 2 72  ? 115.220 102.309 146.532 1.00 57.92  ? 62  HIS B N   1 
ATOM 2488 C CA  . HIS B 2 72  ? 115.479 101.276 147.518 1.00 62.00  ? 62  HIS B CA  1 
ATOM 2489 C C   . HIS B 2 72  ? 115.609 99.945  146.801 1.00 60.90  ? 62  HIS B C   1 
ATOM 2490 O O   . HIS B 2 72  ? 115.013 99.731  145.744 1.00 67.57  ? 62  HIS B O   1 
ATOM 2491 C CB  . HIS B 2 72  ? 114.372 101.207 148.570 1.00 68.38  ? 62  HIS B CB  1 
ATOM 2492 C CG  . HIS B 2 72  ? 114.807 100.596 149.863 1.00 68.42  ? 62  HIS B CG  1 
ATOM 2493 N ND1 . HIS B 2 72  ? 113.984 99.793  150.619 1.00 69.41  ? 62  HIS B ND1 1 
ATOM 2494 C CD2 . HIS B 2 72  ? 115.979 100.672 150.536 1.00 66.00  ? 62  HIS B CD2 1 
ATOM 2495 C CE1 . HIS B 2 72  ? 114.629 99.398  151.701 1.00 66.71  ? 62  HIS B CE1 1 
ATOM 2496 N NE2 . HIS B 2 72  ? 115.841 99.918  151.675 1.00 65.19  ? 62  HIS B NE2 1 
ATOM 2497 N N   . TRP B 2 73  ? 116.398 99.056  147.385 1.00 62.10  ? 63  TRP B N   1 
ATOM 2498 C CA  . TRP B 2 73  ? 116.595 97.729  146.838 1.00 65.33  ? 63  TRP B CA  1 
ATOM 2499 C C   . TRP B 2 73  ? 115.589 96.764  147.452 1.00 73.24  ? 63  TRP B C   1 
ATOM 2500 O O   . TRP B 2 73  ? 114.775 97.128  148.301 1.00 73.34  ? 63  TRP B O   1 
ATOM 2501 C CB  . TRP B 2 73  ? 118.021 97.258  147.096 1.00 72.84  ? 63  TRP B CB  1 
ATOM 2502 C CG  . TRP B 2 73  ? 118.986 97.668  146.049 1.00 77.10  ? 63  TRP B CG  1 
ATOM 2503 C CD1 . TRP B 2 73  ? 119.857 98.706  146.109 1.00 77.06  ? 63  TRP B CD1 1 
ATOM 2504 C CD2 . TRP B 2 73  ? 119.198 97.037  144.785 1.00 78.04  ? 63  TRP B CD2 1 
ATOM 2505 N NE1 . TRP B 2 73  ? 120.597 98.768  144.960 1.00 75.12  ? 63  TRP B NE1 1 
ATOM 2506 C CE2 . TRP B 2 73  ? 120.208 97.755  144.127 1.00 75.04  ? 63  TRP B CE2 1 
ATOM 2507 C CE3 . TRP B 2 73  ? 118.626 95.935  144.144 1.00 76.93  ? 63  TRP B CE3 1 
ATOM 2508 C CZ2 . TRP B 2 73  ? 120.665 97.410  142.864 1.00 71.98  ? 63  TRP B CZ2 1 
ATOM 2509 C CZ3 . TRP B 2 73  ? 119.080 95.595  142.887 1.00 78.42  ? 63  TRP B CZ3 1 
ATOM 2510 C CH2 . TRP B 2 73  ? 120.090 96.330  142.260 1.00 77.06  ? 63  TRP B CH2 1 
ATOM 2511 N N   . GLY B 2 74  ? 115.649 95.507  147.020 1.00 80.21  ? 64  GLY B N   1 
ATOM 2512 C CA  . GLY B 2 74  ? 114.831 94.456  147.573 1.00 85.62  ? 64  GLY B CA  1 
ATOM 2513 C C   . GLY B 2 74  ? 115.650 93.490  148.412 1.00 84.40  ? 64  GLY B C   1 
ATOM 2514 O O   . GLY B 2 74  ? 116.865 93.599  148.545 1.00 85.44  ? 64  GLY B O   1 
ATOM 2515 N N   . THR B 2 75  ? 114.937 92.525  148.992 1.00 78.50  ? 65  THR B N   1 
ATOM 2516 C CA  . THR B 2 75  ? 115.608 91.481  149.755 1.00 82.94  ? 65  THR B CA  1 
ATOM 2517 C C   . THR B 2 75  ? 116.337 90.508  148.838 1.00 90.15  ? 65  THR B C   1 
ATOM 2518 O O   . THR B 2 75  ? 117.349 89.919  149.236 1.00 95.66  ? 65  THR B O   1 
ATOM 2519 C CB  . THR B 2 75  ? 114.598 90.742  150.630 1.00 86.60  ? 65  THR B CB  1 
ATOM 2520 O OG1 . THR B 2 75  ? 113.665 91.683  151.172 1.00 88.35  ? 65  THR B OG1 1 
ATOM 2521 C CG2 . THR B 2 75  ? 115.296 90.027  151.778 1.00 89.72  ? 65  THR B CG2 1 
ATOM 2522 N N   . ASP B 2 76  ? 115.854 90.340  147.609 1.00 88.18  ? 66  ASP B N   1 
ATOM 2523 C CA  . ASP B 2 76  ? 116.479 89.428  146.662 1.00 89.29  ? 66  ASP B CA  1 
ATOM 2524 C C   . ASP B 2 76  ? 117.661 90.045  145.929 1.00 90.47  ? 66  ASP B C   1 
ATOM 2525 O O   . ASP B 2 76  ? 118.317 89.333  145.159 1.00 95.07  ? 66  ASP B O   1 
ATOM 2526 C CB  . ASP B 2 76  ? 115.446 88.944  145.643 1.00 95.31  ? 66  ASP B CB  1 
ATOM 2527 C CG  . ASP B 2 76  ? 114.520 90.053  145.181 1.00 99.07  ? 66  ASP B CG  1 
ATOM 2528 O OD1 . ASP B 2 76  ? 114.724 91.212  145.600 1.00 96.29  ? 66  ASP B OD1 1 
ATOM 2529 O OD2 . ASP B 2 76  ? 113.589 89.766  144.400 1.00 102.64 ? 66  ASP B OD2 1 
ATOM 2530 N N   . SER B 2 77  ? 117.925 91.340  146.140 1.00 89.34  ? 67  SER B N   1 
ATOM 2531 C CA  . SER B 2 77  ? 119.017 92.088  145.504 1.00 88.05  ? 67  SER B CA  1 
ATOM 2532 C C   . SER B 2 77  ? 118.926 92.060  143.981 1.00 88.00  ? 67  SER B C   1 
ATOM 2533 O O   . SER B 2 77  ? 119.943 92.112  143.287 1.00 82.39  ? 67  SER B O   1 
ATOM 2534 C CB  . SER B 2 77  ? 120.388 91.587  145.968 1.00 91.50  ? 67  SER B CB  1 
ATOM 2535 O OG  . SER B 2 77  ? 120.878 90.576  145.106 1.00 97.08  ? 67  SER B OG  1 
ATOM 2536 N N   . ARG B 2 78  ? 117.706 91.989  143.453 1.00 89.33  ? 68  ARG B N   1 
ATOM 2537 C CA  . ARG B 2 78  ? 117.488 91.835  142.023 1.00 84.32  ? 68  ARG B CA  1 
ATOM 2538 C C   . ARG B 2 78  ? 116.507 92.890  141.529 1.00 84.11  ? 68  ARG B C   1 
ATOM 2539 O O   . ARG B 2 78  ? 116.645 93.410  140.418 1.00 84.81  ? 68  ARG B O   1 
ATOM 2540 C CB  . ARG B 2 78  ? 116.989 90.417  141.732 1.00 83.86  ? 68  ARG B CB  1 
ATOM 2541 C CG  . ARG B 2 78  ? 116.500 90.151  140.326 1.00 85.11  ? 68  ARG B CG  1 
ATOM 2542 C CD  . ARG B 2 78  ? 116.517 88.637  140.042 1.00 85.16  ? 68  ARG B CD  1 
ATOM 2543 N NE  . ARG B 2 78  ? 116.502 88.205  138.642 1.00 87.35  ? 68  ARG B NE  1 
ATOM 2544 C CZ  . ARG B 2 78  ? 115.712 88.642  137.665 1.00 89.04  ? 68  ARG B CZ  1 
ATOM 2545 N NH1 . ARG B 2 78  ? 114.632 89.368  137.903 1.00 93.50  ? 68  ARG B NH1 1 
ATOM 2546 N NH2 . ARG B 2 78  ? 115.975 88.277  136.414 1.00 83.19  ? 68  ARG B NH2 1 
ATOM 2547 N N   . LEU B 2 79  ? 115.529 93.226  142.362 1.00 79.53  ? 69  LEU B N   1 
ATOM 2548 C CA  . LEU B 2 79  ? 114.507 94.208  142.038 1.00 75.08  ? 69  LEU B CA  1 
ATOM 2549 C C   . LEU B 2 79  ? 114.755 95.490  142.819 1.00 78.08  ? 69  LEU B C   1 
ATOM 2550 O O   . LEU B 2 79  ? 115.213 95.449  143.965 1.00 85.67  ? 69  LEU B O   1 
ATOM 2551 C CB  . LEU B 2 79  ? 113.115 93.670  142.362 1.00 74.06  ? 69  LEU B CB  1 
ATOM 2552 C CG  . LEU B 2 79  ? 112.609 92.496  141.531 1.00 79.48  ? 69  LEU B CG  1 
ATOM 2553 C CD1 . LEU B 2 79  ? 111.505 91.771  142.273 1.00 75.98  ? 69  LEU B CD1 1 
ATOM 2554 C CD2 . LEU B 2 79  ? 112.118 92.979  140.183 1.00 80.70  ? 69  LEU B CD2 1 
ATOM 2555 N N   . LEU B 2 80  ? 114.451 96.627  142.198 1.00 72.03  ? 70  LEU B N   1 
ATOM 2556 C CA  . LEU B 2 80  ? 114.576 97.914  142.863 1.00 66.86  ? 70  LEU B CA  1 
ATOM 2557 C C   . LEU B 2 80  ? 113.398 98.801  142.490 1.00 63.14  ? 70  LEU B C   1 
ATOM 2558 O O   . LEU B 2 80  ? 112.761 98.624  141.451 1.00 70.73  ? 70  LEU B O   1 
ATOM 2559 C CB  . LEU B 2 80  ? 115.899 98.610  142.520 1.00 64.38  ? 70  LEU B CB  1 
ATOM 2560 C CG  . LEU B 2 80  ? 116.167 99.016  141.075 1.00 64.77  ? 70  LEU B CG  1 
ATOM 2561 C CD1 . LEU B 2 80  ? 116.022 100.514 140.904 1.00 68.55  ? 70  LEU B CD1 1 
ATOM 2562 C CD2 . LEU B 2 80  ? 117.553 98.568  140.656 1.00 71.24  ? 70  LEU B CD2 1 
ATOM 2563 N N   . VAL B 2 81  ? 113.121 99.763  143.363 1.00 57.83  ? 71  VAL B N   1 
ATOM 2564 C CA  . VAL B 2 81  ? 112.022 100.706 143.208 1.00 58.27  ? 71  VAL B CA  1 
ATOM 2565 C C   . VAL B 2 81  ? 112.609 102.101 143.105 1.00 64.05  ? 71  VAL B C   1 
ATOM 2566 O O   . VAL B 2 81  ? 113.425 102.491 143.943 1.00 74.65  ? 71  VAL B O   1 
ATOM 2567 C CB  . VAL B 2 81  ? 111.036 100.612 144.386 1.00 69.62  ? 71  VAL B CB  1 
ATOM 2568 C CG1 . VAL B 2 81  ? 110.196 101.870 144.509 1.00 71.23  ? 71  VAL B CG1 1 
ATOM 2569 C CG2 . VAL B 2 81  ? 110.132 99.434  144.194 1.00 77.12  ? 71  VAL B CG2 1 
ATOM 2570 N N   . SER B 2 82  ? 112.203 102.847 142.083 1.00 65.45  ? 72  SER B N   1 
ATOM 2571 C CA  . SER B 2 82  ? 112.612 104.233 141.914 1.00 68.86  ? 72  SER B CA  1 
ATOM 2572 C C   . SER B 2 82  ? 111.388 105.128 141.972 1.00 67.48  ? 72  SER B C   1 
ATOM 2573 O O   . SER B 2 82  ? 110.390 104.866 141.294 1.00 75.79  ? 72  SER B O   1 
ATOM 2574 C CB  . SER B 2 82  ? 113.339 104.438 140.591 1.00 74.86  ? 72  SER B CB  1 
ATOM 2575 O OG  . SER B 2 82  ? 113.360 105.808 140.237 1.00 80.81  ? 72  SER B OG  1 
ATOM 2576 N N   . ALA B 2 83  ? 111.466 106.182 142.773 1.00 66.54  ? 73  ALA B N   1 
ATOM 2577 C CA  . ALA B 2 83  ? 110.404 107.168 142.881 1.00 74.87  ? 73  ALA B CA  1 
ATOM 2578 C C   . ALA B 2 83  ? 110.911 108.495 142.344 1.00 77.86  ? 73  ALA B C   1 
ATOM 2579 O O   . ALA B 2 83  ? 111.941 108.999 142.801 1.00 83.09  ? 73  ALA B O   1 
ATOM 2580 C CB  . ALA B 2 83  ? 109.936 107.322 144.329 1.00 78.73  ? 73  ALA B CB  1 
ATOM 2581 N N   . SER B 2 84  ? 110.193 109.055 141.380 1.00 75.30  ? 74  SER B N   1 
ATOM 2582 C CA  . SER B 2 84  ? 110.581 110.308 140.757 1.00 76.70  ? 74  SER B CA  1 
ATOM 2583 C C   . SER B 2 84  ? 109.481 111.339 140.939 1.00 76.02  ? 74  SER B C   1 
ATOM 2584 O O   . SER B 2 84  ? 108.353 111.018 141.320 1.00 80.34  ? 74  SER B O   1 
ATOM 2585 C CB  . SER B 2 84  ? 110.884 110.123 139.269 1.00 80.78  ? 74  SER B CB  1 
ATOM 2586 O OG  . SER B 2 84  ? 109.791 109.520 138.605 1.00 88.68  ? 74  SER B OG  1 
ATOM 2587 N N   . GLN B 2 85  ? 109.820 112.589 140.652 1.00 73.81  ? 75  GLN B N   1 
ATOM 2588 C CA  . GLN B 2 85  ? 108.923 113.705 140.900 1.00 78.36  ? 75  GLN B CA  1 
ATOM 2589 C C   . GLN B 2 85  ? 107.926 113.933 139.775 1.00 82.22  ? 75  GLN B C   1 
ATOM 2590 O O   . GLN B 2 85  ? 107.192 114.926 139.815 1.00 86.97  ? 75  GLN B O   1 
ATOM 2591 C CB  . GLN B 2 85  ? 109.730 114.979 141.149 1.00 79.96  ? 75  GLN B CB  1 
ATOM 2592 C CG  . GLN B 2 85  ? 110.786 114.832 142.224 1.00 84.33  ? 75  GLN B CG  1 
ATOM 2593 C CD  . GLN B 2 85  ? 110.391 115.499 143.521 1.00 88.39  ? 75  GLN B CD  1 
ATOM 2594 O OE1 . GLN B 2 85  ? 110.874 116.582 143.849 1.00 91.99  ? 75  GLN B OE1 1 
ATOM 2595 N NE2 . GLN B 2 85  ? 109.510 114.854 144.271 1.00 89.23  ? 75  GLN B NE2 1 
ATOM 2596 N N   . ASP B 2 86  ? 107.878 113.054 138.779 1.00 77.36  ? 76  ASP B N   1 
ATOM 2597 C CA  . ASP B 2 86  ? 106.857 113.135 137.745 1.00 75.96  ? 76  ASP B CA  1 
ATOM 2598 C C   . ASP B 2 86  ? 105.562 112.443 138.139 1.00 78.21  ? 76  ASP B C   1 
ATOM 2599 O O   . ASP B 2 86  ? 104.602 112.470 137.363 1.00 81.78  ? 76  ASP B O   1 
ATOM 2600 C CB  . ASP B 2 86  ? 107.376 112.538 136.432 1.00 83.40  ? 76  ASP B CB  1 
ATOM 2601 C CG  . ASP B 2 86  ? 107.978 111.155 136.608 1.00 91.33  ? 76  ASP B CG  1 
ATOM 2602 O OD1 . ASP B 2 86  ? 107.975 110.630 137.741 1.00 94.16  ? 76  ASP B OD1 1 
ATOM 2603 O OD2 . ASP B 2 86  ? 108.457 110.588 135.604 1.00 93.85  ? 76  ASP B OD2 1 
ATOM 2604 N N   . GLY B 2 87  ? 105.513 111.829 139.316 1.00 81.39  ? 77  GLY B N   1 
ATOM 2605 C CA  . GLY B 2 87  ? 104.339 111.117 139.764 1.00 83.23  ? 77  GLY B CA  1 
ATOM 2606 C C   . GLY B 2 87  ? 104.312 109.645 139.432 1.00 84.31  ? 77  GLY B C   1 
ATOM 2607 O O   . GLY B 2 87  ? 103.244 109.030 139.522 1.00 87.48  ? 77  GLY B O   1 
ATOM 2608 N N   . LYS B 2 88  ? 105.442 109.061 139.048 1.00 78.98  ? 78  LYS B N   1 
ATOM 2609 C CA  . LYS B 2 88  ? 105.512 107.661 138.662 1.00 75.47  ? 78  LYS B CA  1 
ATOM 2610 C C   . LYS B 2 88  ? 106.529 106.927 139.517 1.00 74.34  ? 78  LYS B C   1 
ATOM 2611 O O   . LYS B 2 88  ? 107.618 107.439 139.786 1.00 76.63  ? 78  LYS B O   1 
ATOM 2612 C CB  . LYS B 2 88  ? 105.872 107.507 137.186 1.00 74.34  ? 78  LYS B CB  1 
ATOM 2613 C CG  . LYS B 2 88  ? 104.896 108.176 136.255 1.00 82.90  ? 78  LYS B CG  1 
ATOM 2614 C CD  . LYS B 2 88  ? 104.049 107.145 135.539 1.00 89.30  ? 78  LYS B CD  1 
ATOM 2615 C CE  . LYS B 2 88  ? 102.711 107.728 135.132 1.00 93.55  ? 78  LYS B CE  1 
ATOM 2616 N NZ  . LYS B 2 88  ? 102.781 109.208 135.008 1.00 98.38  ? 78  LYS B NZ  1 
ATOM 2617 N N   . LEU B 2 89  ? 106.159 105.726 139.937 1.00 75.16  ? 79  LEU B N   1 
ATOM 2618 C CA  . LEU B 2 89  ? 107.028 104.829 140.681 1.00 68.63  ? 79  LEU B CA  1 
ATOM 2619 C C   . LEU B 2 89  ? 107.234 103.582 139.835 1.00 67.38  ? 79  LEU B C   1 
ATOM 2620 O O   . LEU B 2 89  ? 106.262 102.933 139.438 1.00 73.95  ? 79  LEU B O   1 
ATOM 2621 C CB  . LEU B 2 89  ? 106.410 104.484 142.032 1.00 70.72  ? 79  LEU B CB  1 
ATOM 2622 C CG  . LEU B 2 89  ? 107.236 103.690 143.032 1.00 71.79  ? 79  LEU B CG  1 
ATOM 2623 C CD1 . LEU B 2 89  ? 107.081 104.291 144.413 1.00 75.36  ? 79  LEU B CD1 1 
ATOM 2624 C CD2 . LEU B 2 89  ? 106.791 102.244 143.028 1.00 71.08  ? 79  LEU B CD2 1 
ATOM 2625 N N   . ILE B 2 90  ? 108.490 103.248 139.563 1.00 59.04  ? 80  ILE B N   1 
ATOM 2626 C CA  . ILE B 2 90  ? 108.832 102.197 138.617 1.00 53.98  ? 80  ILE B CA  1 
ATOM 2627 C C   . ILE B 2 90  ? 109.587 101.110 139.362 1.00 54.16  ? 80  ILE B C   1 
ATOM 2628 O O   . ILE B 2 90  ? 110.600 101.387 140.014 1.00 64.64  ? 80  ILE B O   1 
ATOM 2629 C CB  . ILE B 2 90  ? 109.668 102.739 137.449 1.00 60.51  ? 80  ILE B CB  1 
ATOM 2630 C CG1 . ILE B 2 90  ? 108.815 103.642 136.566 1.00 66.30  ? 80  ILE B CG1 1 
ATOM 2631 C CG2 . ILE B 2 90  ? 110.215 101.600 136.615 1.00 66.37  ? 80  ILE B CG2 1 
ATOM 2632 C CD1 . ILE B 2 90  ? 109.571 104.239 135.410 1.00 74.95  ? 80  ILE B CD1 1 
ATOM 2633 N N   . ILE B 2 91  ? 109.094 99.882  139.272 1.00 54.84  ? 81  ILE B N   1 
ATOM 2634 C CA  . ILE B 2 91  ? 109.812 98.723  139.779 1.00 53.81  ? 81  ILE B CA  1 
ATOM 2635 C C   . ILE B 2 91  ? 110.714 98.224  138.664 1.00 62.38  ? 81  ILE B C   1 
ATOM 2636 O O   . ILE B 2 91  ? 110.235 97.840  137.592 1.00 68.87  ? 81  ILE B O   1 
ATOM 2637 C CB  . ILE B 2 91  ? 108.848 97.623  140.237 1.00 59.44  ? 81  ILE B CB  1 
ATOM 2638 C CG1 . ILE B 2 91  ? 108.106 98.062  141.491 1.00 66.69  ? 81  ILE B CG1 1 
ATOM 2639 C CG2 . ILE B 2 91  ? 109.611 96.344  140.510 1.00 59.29  ? 81  ILE B CG2 1 
ATOM 2640 C CD1 . ILE B 2 91  ? 107.222 97.000  142.072 1.00 75.33  ? 81  ILE B CD1 1 
ATOM 2641 N N   . TRP B 2 92  ? 112.016 98.230  138.909 1.00 61.87  ? 82  TRP B N   1 
ATOM 2642 C CA  . TRP B 2 92  ? 112.992 97.863  137.898 1.00 58.48  ? 82  TRP B CA  1 
ATOM 2643 C C   . TRP B 2 92  ? 113.478 96.440  138.115 1.00 64.92  ? 82  TRP B C   1 
ATOM 2644 O O   . TRP B 2 92  ? 113.483 95.929  139.236 1.00 73.66  ? 82  TRP B O   1 
ATOM 2645 C CB  . TRP B 2 92  ? 114.190 98.808  137.925 1.00 60.24  ? 82  TRP B CB  1 
ATOM 2646 C CG  . TRP B 2 92  ? 113.985 100.086 137.208 1.00 62.05  ? 82  TRP B CG  1 
ATOM 2647 C CD1 . TRP B 2 92  ? 113.586 101.268 137.744 1.00 65.30  ? 82  TRP B CD1 1 
ATOM 2648 C CD2 . TRP B 2 92  ? 114.165 100.318 135.812 1.00 69.95  ? 82  TRP B CD2 1 
ATOM 2649 N NE1 . TRP B 2 92  ? 113.517 102.230 136.771 1.00 68.12  ? 82  TRP B NE1 1 
ATOM 2650 C CE2 . TRP B 2 92  ? 113.865 101.669 135.573 1.00 71.35  ? 82  TRP B CE2 1 
ATOM 2651 C CE3 . TRP B 2 92  ? 114.555 99.512  134.739 1.00 79.79  ? 82  TRP B CE3 1 
ATOM 2652 C CZ2 . TRP B 2 92  ? 113.937 102.234 134.307 1.00 77.88  ? 82  TRP B CZ2 1 
ATOM 2653 C CZ3 . TRP B 2 92  ? 114.630 100.075 133.482 1.00 83.03  ? 82  TRP B CZ3 1 
ATOM 2654 C CH2 . TRP B 2 92  ? 114.321 101.423 133.275 1.00 82.68  ? 82  TRP B CH2 1 
ATOM 2655 N N   . ASP B 2 93  ? 113.884 95.806  137.028 1.00 66.16  ? 83  ASP B N   1 
ATOM 2656 C CA  . ASP B 2 93  ? 114.581 94.527  137.070 1.00 74.22  ? 83  ASP B CA  1 
ATOM 2657 C C   . ASP B 2 93  ? 116.038 94.823  136.741 1.00 82.92  ? 83  ASP B C   1 
ATOM 2658 O O   . ASP B 2 93  ? 116.385 95.065  135.581 1.00 87.00  ? 83  ASP B O   1 
ATOM 2659 C CB  . ASP B 2 93  ? 113.970 93.529  136.096 1.00 80.65  ? 83  ASP B CB  1 
ATOM 2660 C CG  . ASP B 2 93  ? 114.441 92.119  136.341 1.00 84.65  ? 83  ASP B CG  1 
ATOM 2661 O OD1 . ASP B 2 93  ? 115.538 91.766  135.866 1.00 85.02  ? 83  ASP B OD1 1 
ATOM 2662 O OD2 . ASP B 2 93  ? 113.715 91.359  137.011 1.00 90.56  ? 83  ASP B OD2 1 
ATOM 2663 N N   . SER B 2 94  ? 116.887 94.813  137.769 1.00 81.34  ? 84  SER B N   1 
ATOM 2664 C CA  . SER B 2 94  ? 118.259 95.274  137.615 1.00 81.35  ? 84  SER B CA  1 
ATOM 2665 C C   . SER B 2 94  ? 119.117 94.314  136.810 1.00 79.47  ? 84  SER B C   1 
ATOM 2666 O O   . SER B 2 94  ? 120.153 94.727  136.283 1.00 82.17  ? 84  SER B O   1 
ATOM 2667 C CB  . SER B 2 94  ? 118.892 95.497  138.985 1.00 84.22  ? 84  SER B CB  1 
ATOM 2668 O OG  . SER B 2 94  ? 119.505 94.311  139.459 1.00 85.96  ? 84  SER B OG  1 
ATOM 2669 N N   . TYR B 2 95  ? 118.726 93.046  136.716 1.00 76.71  ? 85  TYR B N   1 
ATOM 2670 C CA  . TYR B 2 95  ? 119.527 92.093  135.961 1.00 73.14  ? 85  TYR B CA  1 
ATOM 2671 C C   . TYR B 2 95  ? 119.366 92.289  134.459 1.00 73.39  ? 85  TYR B C   1 
ATOM 2672 O O   . TYR B 2 95  ? 120.347 92.208  133.713 1.00 75.38  ? 85  TYR B O   1 
ATOM 2673 C CB  . TYR B 2 95  ? 119.152 90.666  136.351 1.00 73.21  ? 85  TYR B CB  1 
ATOM 2674 C CG  . TYR B 2 95  ? 119.808 90.161  137.614 1.00 73.63  ? 85  TYR B CG  1 
ATOM 2675 C CD1 . TYR B 2 95  ? 120.552 91.002  138.424 1.00 76.04  ? 85  TYR B CD1 1 
ATOM 2676 C CD2 . TYR B 2 95  ? 119.675 88.835  137.998 1.00 76.62  ? 85  TYR B CD2 1 
ATOM 2677 C CE1 . TYR B 2 95  ? 121.147 90.537  139.579 1.00 79.33  ? 85  TYR B CE1 1 
ATOM 2678 C CE2 . TYR B 2 95  ? 120.264 88.363  139.149 1.00 76.52  ? 85  TYR B CE2 1 
ATOM 2679 C CZ  . TYR B 2 95  ? 120.998 89.216  139.935 1.00 78.68  ? 85  TYR B CZ  1 
ATOM 2680 O OH  . TYR B 2 95  ? 121.588 88.748  141.083 1.00 82.23  ? 85  TYR B OH  1 
ATOM 2681 N N   . THR B 2 96  ? 118.142 92.551  133.998 1.00 72.72  ? 86  THR B N   1 
ATOM 2682 C CA  . THR B 2 96  ? 117.834 92.571  132.572 1.00 74.07  ? 86  THR B CA  1 
ATOM 2683 C C   . THR B 2 96  ? 117.274 93.909  132.102 1.00 74.99  ? 86  THR B C   1 
ATOM 2684 O O   . THR B 2 96  ? 116.626 93.957  131.053 1.00 79.76  ? 86  THR B O   1 
ATOM 2685 C CB  . THR B 2 96  ? 116.854 91.450  132.223 1.00 79.29  ? 86  THR B CB  1 
ATOM 2686 O OG1 . THR B 2 96  ? 115.660 91.601  133.000 1.00 83.21  ? 86  THR B OG1 1 
ATOM 2687 C CG2 . THR B 2 96  ? 117.468 90.085  132.500 1.00 75.92  ? 86  THR B CG2 1 
ATOM 2688 N N   . THR B 2 97  ? 117.523 94.992  132.853 1.00 75.02  ? 87  THR B N   1 
ATOM 2689 C CA  . THR B 2 97  ? 117.104 96.368  132.520 1.00 77.04  ? 87  THR B CA  1 
ATOM 2690 C C   . THR B 2 97  ? 115.608 96.480  132.240 1.00 75.06  ? 87  THR B C   1 
ATOM 2691 O O   . THR B 2 97  ? 115.179 97.306  131.433 1.00 74.63  ? 87  THR B O   1 
ATOM 2692 C CB  . THR B 2 97  ? 117.884 96.945  131.330 1.00 83.19  ? 87  THR B CB  1 
ATOM 2693 O OG1 . THR B 2 97  ? 117.288 96.504  130.104 1.00 87.05  ? 87  THR B OG1 1 
ATOM 2694 C CG2 . THR B 2 97  ? 119.350 96.550  131.360 1.00 78.58  ? 87  THR B CG2 1 
ATOM 2695 N N   . ASN B 2 98  ? 114.800 95.661  132.898 1.00 75.63  ? 88  ASN B N   1 
ATOM 2696 C CA  . ASN B 2 98  ? 113.381 95.589  132.589 1.00 77.45  ? 88  ASN B CA  1 
ATOM 2697 C C   . ASN B 2 98  ? 112.556 96.364  133.605 1.00 77.35  ? 88  ASN B C   1 
ATOM 2698 O O   . ASN B 2 98  ? 112.967 96.580  134.747 1.00 83.85  ? 88  ASN B O   1 
ATOM 2699 C CB  . ASN B 2 98  ? 112.905 94.137  132.539 1.00 77.93  ? 88  ASN B CB  1 
ATOM 2700 C CG  . ASN B 2 98  ? 113.547 93.350  131.421 1.00 84.04  ? 88  ASN B CG  1 
ATOM 2701 O OD1 . ASN B 2 98  ? 113.670 92.130  131.499 1.00 87.63  ? 88  ASN B OD1 1 
ATOM 2702 N ND2 . ASN B 2 98  ? 113.963 94.044  130.369 1.00 84.16  ? 88  ASN B ND2 1 
ATOM 2703 N N   . LYS B 2 99  ? 111.375 96.785  133.167 1.00 66.71  ? 89  LYS B N   1 
ATOM 2704 C CA  . LYS B 2 99  ? 110.391 97.417  134.031 1.00 67.08  ? 89  LYS B CA  1 
ATOM 2705 C C   . LYS B 2 99  ? 109.279 96.417  134.306 1.00 69.21  ? 89  LYS B C   1 
ATOM 2706 O O   . LYS B 2 99  ? 108.678 95.881  133.370 1.00 77.00  ? 89  LYS B O   1 
ATOM 2707 C CB  . LYS B 2 99  ? 109.829 98.684  133.391 1.00 70.09  ? 89  LYS B CB  1 
ATOM 2708 C CG  . LYS B 2 99  ? 110.844 99.495  132.618 1.00 71.87  ? 89  LYS B CG  1 
ATOM 2709 C CD  . LYS B 2 99  ? 110.344 100.905 132.386 1.00 75.53  ? 89  LYS B CD  1 
ATOM 2710 C CE  . LYS B 2 99  ? 111.230 101.654 131.413 1.00 85.96  ? 89  LYS B CE  1 
ATOM 2711 N NZ  . LYS B 2 99  ? 111.676 100.790 130.287 1.00 89.05  ? 89  LYS B NZ  1 
ATOM 2712 N N   . VAL B 2 100 ? 109.010 96.166  135.581 1.00 60.54  ? 90  VAL B N   1 
ATOM 2713 C CA  . VAL B 2 100 ? 107.977 95.212  135.965 1.00 60.22  ? 90  VAL B CA  1 
ATOM 2714 C C   . VAL B 2 100 ? 106.639 95.903  136.180 1.00 68.10  ? 90  VAL B C   1 
ATOM 2715 O O   . VAL B 2 100 ? 105.601 95.430  135.711 1.00 75.99  ? 90  VAL B O   1 
ATOM 2716 C CB  . VAL B 2 100 ? 108.417 94.435  137.221 1.00 57.73  ? 90  VAL B CB  1 
ATOM 2717 C CG1 . VAL B 2 100 ? 107.640 93.139  137.332 1.00 61.80  ? 90  VAL B CG1 1 
ATOM 2718 C CG2 . VAL B 2 100 ? 109.906 94.162  137.176 1.00 63.96  ? 90  VAL B CG2 1 
ATOM 2719 N N   . HIS B 2 101 ? 106.639 97.027  136.891 1.00 62.91  ? 91  HIS B N   1 
ATOM 2720 C CA  . HIS B 2 101 ? 105.441 97.828  137.084 1.00 59.47  ? 91  HIS B CA  1 
ATOM 2721 C C   . HIS B 2 101 ? 105.806 99.301  137.018 1.00 62.25  ? 91  HIS B C   1 
ATOM 2722 O O   . HIS B 2 101 ? 106.946 99.686  137.286 1.00 72.36  ? 91  HIS B O   1 
ATOM 2723 C CB  . HIS B 2 101 ? 104.759 97.535  138.421 1.00 60.58  ? 91  HIS B CB  1 
ATOM 2724 C CG  . HIS B 2 101 ? 104.379 96.102  138.609 1.00 68.39  ? 91  HIS B CG  1 
ATOM 2725 N ND1 . HIS B 2 101 ? 105.265 95.152  139.067 1.00 69.48  ? 91  HIS B ND1 1 
ATOM 2726 C CD2 . HIS B 2 101 ? 103.205 95.458  138.414 1.00 72.50  ? 91  HIS B CD2 1 
ATOM 2727 C CE1 . HIS B 2 101 ? 104.655 93.984  139.142 1.00 71.67  ? 91  HIS B CE1 1 
ATOM 2728 N NE2 . HIS B 2 101 ? 103.404 94.142  138.750 1.00 74.43  ? 91  HIS B NE2 1 
ATOM 2729 N N   . ALA B 2 102 ? 104.825 100.123 136.660 1.00 61.50  ? 92  ALA B N   1 
ATOM 2730 C CA  . ALA B 2 102 ? 104.975 101.576 136.615 1.00 65.50  ? 92  ALA B CA  1 
ATOM 2731 C C   . ALA B 2 102 ? 103.759 102.157 137.324 1.00 73.68  ? 92  ALA B C   1 
ATOM 2732 O O   . ALA B 2 102 ? 102.751 102.477 136.690 1.00 79.54  ? 92  ALA B O   1 
ATOM 2733 C CB  . ALA B 2 102 ? 105.098 102.082 135.183 1.00 62.97  ? 92  ALA B CB  1 
ATOM 2734 N N   . ILE B 2 103 ? 103.861 102.294 138.640 1.00 70.10  ? 93  ILE B N   1 
ATOM 2735 C CA  . ILE B 2 103 ? 102.736 102.696 139.475 1.00 71.28  ? 93  ILE B CA  1 
ATOM 2736 C C   . ILE B 2 103 ? 102.537 104.203 139.383 1.00 76.29  ? 93  ILE B C   1 
ATOM 2737 O O   . ILE B 2 103 ? 103.454 104.969 139.714 1.00 79.78  ? 93  ILE B O   1 
ATOM 2738 C CB  . ILE B 2 103 ? 102.952 102.261 140.931 1.00 71.01  ? 93  ILE B CB  1 
ATOM 2739 C CG1 . ILE B 2 103 ? 102.930 100.738 141.038 1.00 75.81  ? 93  ILE B CG1 1 
ATOM 2740 C CG2 . ILE B 2 103 ? 101.892 102.867 141.833 1.00 73.70  ? 93  ILE B CG2 1 
ATOM 2741 C CD1 . ILE B 2 103 ? 104.286 100.117 141.260 1.00 81.47  ? 93  ILE B CD1 1 
ATOM 2742 N N   . PRO B 2 104 ? 101.376 104.674 138.942 1.00 75.51  ? 94  PRO B N   1 
ATOM 2743 C CA  . PRO B 2 104 ? 101.084 106.105 139.022 1.00 74.20  ? 94  PRO B CA  1 
ATOM 2744 C C   . PRO B 2 104 ? 100.697 106.493 140.438 1.00 79.70  ? 94  PRO B C   1 
ATOM 2745 O O   . PRO B 2 104 ? 100.133 105.700 141.195 1.00 86.23  ? 94  PRO B O   1 
ATOM 2746 C CB  . PRO B 2 104 ? 99.912  106.278 138.053 1.00 76.68  ? 94  PRO B CB  1 
ATOM 2747 C CG  . PRO B 2 104 ? 99.220  104.963 138.087 1.00 77.02  ? 94  PRO B CG  1 
ATOM 2748 C CD  . PRO B 2 104 ? 100.268 103.915 138.339 1.00 73.58  ? 94  PRO B CD  1 
ATOM 2749 N N   . LEU B 2 105 ? 101.009 107.733 140.794 1.00 78.39  ? 95  LEU B N   1 
ATOM 2750 C CA  . LEU B 2 105 ? 100.861 108.201 142.162 1.00 79.41  ? 95  LEU B CA  1 
ATOM 2751 C C   . LEU B 2 105 ? 99.840  109.326 142.234 1.00 78.59  ? 95  LEU B C   1 
ATOM 2752 O O   . LEU B 2 105 ? 99.654  110.081 141.277 1.00 82.47  ? 95  LEU B O   1 
ATOM 2753 C CB  . LEU B 2 105 ? 102.199 108.675 142.725 1.00 80.57  ? 95  LEU B CB  1 
ATOM 2754 C CG  . LEU B 2 105 ? 103.337 107.663 142.605 1.00 81.84  ? 95  LEU B CG  1 
ATOM 2755 C CD1 . LEU B 2 105 ? 104.631 108.253 143.119 1.00 83.27  ? 95  LEU B CD1 1 
ATOM 2756 C CD2 . LEU B 2 105 ? 102.999 106.384 143.349 1.00 79.48  ? 95  LEU B CD2 1 
ATOM 2757 N N   . ARG B 2 106 ? 99.174  109.420 143.387 1.00 74.82  ? 96  ARG B N   1 
ATOM 2758 C CA  . ARG B 2 106 ? 98.165  110.454 143.587 1.00 74.39  ? 96  ARG B CA  1 
ATOM 2759 C C   . ARG B 2 106 ? 98.797  111.837 143.686 1.00 79.27  ? 96  ARG B C   1 
ATOM 2760 O O   . ARG B 2 106 ? 98.215  112.824 143.224 1.00 82.32  ? 96  ARG B O   1 
ATOM 2761 C CB  . ARG B 2 106 ? 97.345  110.149 144.837 1.00 74.01  ? 96  ARG B CB  1 
ATOM 2762 C CG  . ARG B 2 106 ? 95.894  110.574 144.741 1.00 86.96  ? 96  ARG B CG  1 
ATOM 2763 C CD  . ARG B 2 106 ? 95.009  109.711 145.622 1.00 104.12 ? 96  ARG B CD  1 
ATOM 2764 N NE  . ARG B 2 106 ? 94.470  108.567 144.898 1.00 117.53 ? 96  ARG B NE  1 
ATOM 2765 C CZ  . ARG B 2 106 ? 93.219  108.476 144.466 1.00 122.00 ? 96  ARG B CZ  1 
ATOM 2766 N NH1 . ARG B 2 106 ? 92.345  109.448 144.670 1.00 125.62 ? 96  ARG B NH1 1 
ATOM 2767 N NH2 . ARG B 2 106 ? 92.836  107.382 143.814 1.00 117.57 ? 96  ARG B NH2 1 
ATOM 2768 N N   . SER B 2 107 ? 99.979  111.929 144.284 1.00 80.74  ? 97  SER B N   1 
ATOM 2769 C CA  . SER B 2 107 ? 100.704 113.185 144.406 1.00 78.07  ? 97  SER B CA  1 
ATOM 2770 C C   . SER B 2 107 ? 101.974 113.125 143.572 1.00 78.15  ? 97  SER B C   1 
ATOM 2771 O O   . SER B 2 107 ? 102.682 112.114 143.574 1.00 79.47  ? 97  SER B O   1 
ATOM 2772 C CB  . SER B 2 107 ? 101.053 113.483 145.863 1.00 82.03  ? 97  SER B CB  1 
ATOM 2773 O OG  . SER B 2 107 ? 101.723 114.725 145.978 1.00 85.84  ? 97  SER B OG  1 
ATOM 2774 N N   . SER B 2 108 ? 102.254 114.214 142.856 1.00 79.15  ? 98  SER B N   1 
ATOM 2775 C CA  . SER B 2 108 ? 103.396 114.227 141.951 1.00 81.35  ? 98  SER B CA  1 
ATOM 2776 C C   . SER B 2 108 ? 104.717 114.299 142.702 1.00 81.19  ? 98  SER B C   1 
ATOM 2777 O O   . SER B 2 108 ? 105.724 113.761 142.231 1.00 82.71  ? 98  SER B O   1 
ATOM 2778 C CB  . SER B 2 108 ? 103.280 115.398 140.978 1.00 84.85  ? 98  SER B CB  1 
ATOM 2779 O OG  . SER B 2 108 ? 104.509 115.625 140.313 1.00 86.26  ? 98  SER B OG  1 
ATOM 2780 N N   . TRP B 2 109 ? 104.736 114.949 143.860 1.00 78.14  ? 99  TRP B N   1 
ATOM 2781 C CA  . TRP B 2 109 ? 105.960 115.125 144.627 1.00 77.67  ? 99  TRP B CA  1 
ATOM 2782 C C   . TRP B 2 109 ? 106.118 114.014 145.651 1.00 77.15  ? 99  TRP B C   1 
ATOM 2783 O O   . TRP B 2 109 ? 105.324 113.904 146.589 1.00 81.10  ? 99  TRP B O   1 
ATOM 2784 C CB  . TRP B 2 109 ? 105.974 116.488 145.308 1.00 77.95  ? 99  TRP B CB  1 
ATOM 2785 C CG  . TRP B 2 109 ? 105.442 117.558 144.441 1.00 76.65  ? 99  TRP B CG  1 
ATOM 2786 C CD1 . TRP B 2 109 ? 104.186 118.074 144.442 1.00 73.42  ? 99  TRP B CD1 1 
ATOM 2787 C CD2 . TRP B 2 109 ? 106.165 118.254 143.427 1.00 79.86  ? 99  TRP B CD2 1 
ATOM 2788 N NE1 . TRP B 2 109 ? 104.080 119.053 143.488 1.00 72.81  ? 99  TRP B NE1 1 
ATOM 2789 C CE2 . TRP B 2 109 ? 105.286 119.182 142.852 1.00 75.92  ? 99  TRP B CE2 1 
ATOM 2790 C CE3 . TRP B 2 109 ? 107.476 118.182 142.951 1.00 82.52  ? 99  TRP B CE3 1 
ATOM 2791 C CZ2 . TRP B 2 109 ? 105.673 120.032 141.826 1.00 79.05  ? 99  TRP B CZ2 1 
ATOM 2792 C CZ3 . TRP B 2 109 ? 107.857 119.025 141.931 1.00 80.51  ? 99  TRP B CZ3 1 
ATOM 2793 C CH2 . TRP B 2 109 ? 106.960 119.938 141.379 1.00 81.87  ? 99  TRP B CH2 1 
ATOM 2794 N N   . VAL B 2 110 ? 107.151 113.200 145.468 1.00 74.93  ? 100 VAL B N   1 
ATOM 2795 C CA  . VAL B 2 110 ? 107.550 112.185 146.428 1.00 77.64  ? 100 VAL B CA  1 
ATOM 2796 C C   . VAL B 2 110 ? 109.033 112.355 146.709 1.00 80.60  ? 100 VAL B C   1 
ATOM 2797 O O   . VAL B 2 110 ? 109.804 112.782 145.844 1.00 88.07  ? 100 VAL B O   1 
ATOM 2798 C CB  . VAL B 2 110 ? 107.240 110.757 145.929 1.00 77.12  ? 100 VAL B CB  1 
ATOM 2799 C CG1 . VAL B 2 110 ? 105.747 110.568 145.820 1.00 84.14  ? 100 VAL B CG1 1 
ATOM 2800 C CG2 . VAL B 2 110 ? 107.899 110.493 144.588 1.00 75.51  ? 100 VAL B CG2 1 
ATOM 2801 N N   . MET B 2 111 ? 109.428 112.067 147.948 1.00 78.53  ? 101 MET B N   1 
ATOM 2802 C CA  . MET B 2 111 ? 110.841 112.057 148.288 1.00 82.52  ? 101 MET B CA  1 
ATOM 2803 C C   . MET B 2 111 ? 111.264 110.772 148.984 1.00 84.38  ? 101 MET B C   1 
ATOM 2804 O O   . MET B 2 111 ? 112.398 110.691 149.468 1.00 86.91  ? 101 MET B O   1 
ATOM 2805 C CB  . MET B 2 111 ? 111.220 113.245 149.170 1.00 83.48  ? 101 MET B CB  1 
ATOM 2806 C CG  . MET B 2 111 ? 110.258 114.399 149.202 1.00 85.14  ? 101 MET B CG  1 
ATOM 2807 S SD  . MET B 2 111 ? 111.203 115.855 149.649 1.00 118.31 ? 101 MET B SD  1 
ATOM 2808 C CE  . MET B 2 111 ? 111.382 115.571 151.397 1.00 96.32  ? 101 MET B CE  1 
ATOM 2809 N N   . THR B 2 112 ? 110.392 109.771 149.051 1.00 81.57  ? 102 THR B N   1 
ATOM 2810 C CA  . THR B 2 112 ? 110.755 108.517 149.683 1.00 79.28  ? 102 THR B CA  1 
ATOM 2811 C C   . THR B 2 112 ? 110.007 107.374 149.022 1.00 81.28  ? 102 THR B C   1 
ATOM 2812 O O   . THR B 2 112 ? 108.898 107.537 148.506 1.00 90.28  ? 102 THR B O   1 
ATOM 2813 C CB  . THR B 2 112 ? 110.468 108.536 151.184 1.00 84.95  ? 102 THR B CB  1 
ATOM 2814 O OG1 . THR B 2 112 ? 110.646 107.222 151.724 1.00 89.55  ? 102 THR B OG1 1 
ATOM 2815 C CG2 . THR B 2 112 ? 109.054 109.009 151.460 1.00 87.69  ? 102 THR B CG2 1 
ATOM 2816 N N   . CYS B 2 113 ? 110.644 106.210 149.037 1.00 75.95  ? 103 CYS B N   1 
ATOM 2817 C CA  . CYS B 2 113 ? 110.019 104.976 148.599 1.00 74.50  ? 103 CYS B CA  1 
ATOM 2818 C C   . CYS B 2 113 ? 110.677 103.834 149.351 1.00 74.26  ? 103 CYS B C   1 
ATOM 2819 O O   . CYS B 2 113 ? 111.844 103.914 149.737 1.00 80.93  ? 103 CYS B O   1 
ATOM 2820 C CB  . CYS B 2 113 ? 110.144 104.781 147.087 1.00 78.01  ? 103 CYS B CB  1 
ATOM 2821 S SG  . CYS B 2 113 ? 111.838 104.812 146.477 1.00 90.92  ? 103 CYS B SG  1 
ATOM 2822 N N   . ALA B 2 114 ? 109.915 102.768 149.565 1.00 69.23  ? 104 ALA B N   1 
ATOM 2823 C CA  . ALA B 2 114 ? 110.423 101.646 150.331 1.00 70.31  ? 104 ALA B CA  1 
ATOM 2824 C C   . ALA B 2 114 ? 109.974 100.349 149.682 1.00 73.55  ? 104 ALA B C   1 
ATOM 2825 O O   . ALA B 2 114 ? 108.965 100.306 148.976 1.00 77.57  ? 104 ALA B O   1 
ATOM 2826 C CB  . ALA B 2 114 ? 109.953 101.700 151.788 1.00 73.44  ? 104 ALA B CB  1 
ATOM 2827 N N   . TYR B 2 115 ? 110.742 99.296  149.925 1.00 75.43  ? 105 TYR B N   1 
ATOM 2828 C CA  . TYR B 2 115 ? 110.418 97.950  149.481 1.00 77.13  ? 105 TYR B CA  1 
ATOM 2829 C C   . TYR B 2 115 ? 110.271 97.081  150.718 1.00 73.85  ? 105 TYR B C   1 
ATOM 2830 O O   . TYR B 2 115 ? 111.170 97.050  151.564 1.00 74.61  ? 105 TYR B O   1 
ATOM 2831 C CB  . TYR B 2 115 ? 111.504 97.400  148.557 1.00 77.77  ? 105 TYR B CB  1 
ATOM 2832 C CG  . TYR B 2 115 ? 111.030 96.350  147.581 1.00 84.04  ? 105 TYR B CG  1 
ATOM 2833 C CD1 . TYR B 2 115 ? 110.917 95.022  147.959 1.00 91.15  ? 105 TYR B CD1 1 
ATOM 2834 C CD2 . TYR B 2 115 ? 110.710 96.685  146.281 1.00 77.63  ? 105 TYR B CD2 1 
ATOM 2835 C CE1 . TYR B 2 115 ? 110.490 94.065  147.065 1.00 93.36  ? 105 TYR B CE1 1 
ATOM 2836 C CE2 . TYR B 2 115 ? 110.280 95.738  145.382 1.00 80.72  ? 105 TYR B CE2 1 
ATOM 2837 C CZ  . TYR B 2 115 ? 110.170 94.429  145.778 1.00 91.48  ? 105 TYR B CZ  1 
ATOM 2838 O OH  . TYR B 2 115 ? 109.743 93.476  144.885 1.00 96.11  ? 105 TYR B OH  1 
ATOM 2839 N N   . ALA B 2 116 ? 109.140 96.398  150.829 1.00 72.61  ? 106 ALA B N   1 
ATOM 2840 C CA  . ALA B 2 116 ? 108.901 95.549  151.984 1.00 76.08  ? 106 ALA B CA  1 
ATOM 2841 C C   . ALA B 2 116 ? 109.838 94.346  151.949 1.00 78.58  ? 106 ALA B C   1 
ATOM 2842 O O   . ALA B 2 116 ? 110.175 93.857  150.867 1.00 83.17  ? 106 ALA B O   1 
ATOM 2843 C CB  . ALA B 2 116 ? 107.447 95.082  152.014 1.00 82.85  ? 106 ALA B CB  1 
ATOM 2844 N N   . PRO B 2 117 ? 110.303 93.873  153.109 1.00 79.13  ? 107 PRO B N   1 
ATOM 2845 C CA  . PRO B 2 117 ? 111.178 92.689  153.126 1.00 80.28  ? 107 PRO B CA  1 
ATOM 2846 C C   . PRO B 2 117 ? 110.521 91.428  152.594 1.00 87.41  ? 107 PRO B C   1 
ATOM 2847 O O   . PRO B 2 117 ? 111.222 90.542  152.090 1.00 90.67  ? 107 PRO B O   1 
ATOM 2848 C CB  . PRO B 2 117 ? 111.543 92.550  154.609 1.00 75.60  ? 107 PRO B CB  1 
ATOM 2849 C CG  . PRO B 2 117 ? 111.368 93.912  155.168 1.00 84.28  ? 107 PRO B CG  1 
ATOM 2850 C CD  . PRO B 2 117 ? 110.204 94.501  154.436 1.00 85.50  ? 107 PRO B CD  1 
ATOM 2851 N N   . SER B 2 118 ? 109.198 91.319  152.686 1.00 84.77  ? 108 SER B N   1 
ATOM 2852 C CA  . SER B 2 118 ? 108.493 90.182  152.115 1.00 82.66  ? 108 SER B CA  1 
ATOM 2853 C C   . SER B 2 118 ? 108.253 90.327  150.620 1.00 83.86  ? 108 SER B C   1 
ATOM 2854 O O   . SER B 2 118 ? 107.779 89.375  149.993 1.00 93.91  ? 108 SER B O   1 
ATOM 2855 C CB  . SER B 2 118 ? 107.156 89.977  152.830 1.00 90.55  ? 108 SER B CB  1 
ATOM 2856 O OG  . SER B 2 118 ? 106.421 88.919  152.241 1.00 98.94  ? 108 SER B OG  1 
ATOM 2857 N N   . GLY B 2 119 ? 108.565 91.482  150.039 1.00 77.69  ? 109 GLY B N   1 
ATOM 2858 C CA  . GLY B 2 119 ? 108.412 91.659  148.611 1.00 80.84  ? 109 GLY B CA  1 
ATOM 2859 C C   . GLY B 2 119 ? 106.991 91.808  148.127 1.00 86.20  ? 109 GLY B C   1 
ATOM 2860 O O   . GLY B 2 119 ? 106.725 91.579  146.946 1.00 87.98  ? 109 GLY B O   1 
ATOM 2861 N N   . ASN B 2 120 ? 106.065 92.189  149.006 1.00 86.03  ? 110 ASN B N   1 
ATOM 2862 C CA  . ASN B 2 120 ? 104.660 92.293  148.646 1.00 86.07  ? 110 ASN B CA  1 
ATOM 2863 C C   . ASN B 2 120 ? 104.141 93.719  148.583 1.00 86.77  ? 110 ASN B C   1 
ATOM 2864 O O   . ASN B 2 120 ? 103.096 93.947  147.968 1.00 92.79  ? 110 ASN B O   1 
ATOM 2865 C CB  . ASN B 2 120 ? 103.796 91.507  149.642 1.00 90.20  ? 110 ASN B CB  1 
ATOM 2866 C CG  . ASN B 2 120 ? 104.214 90.058  149.761 1.00 93.30  ? 110 ASN B CG  1 
ATOM 2867 O OD1 . ASN B 2 120 ? 104.969 89.548  148.936 1.00 98.51  ? 110 ASN B OD1 1 
ATOM 2868 N ND2 . ASN B 2 120 ? 103.719 89.383  150.790 1.00 87.25  ? 110 ASN B ND2 1 
ATOM 2869 N N   . TYR B 2 121 ? 104.829 94.676  149.196 1.00 82.70  ? 111 TYR B N   1 
ATOM 2870 C CA  . TYR B 2 121 ? 104.338 96.040  149.295 1.00 75.25  ? 111 TYR B CA  1 
ATOM 2871 C C   . TYR B 2 121 ? 105.439 97.023  148.934 1.00 75.22  ? 111 TYR B C   1 
ATOM 2872 O O   . TYR B 2 121 ? 106.624 96.761  149.151 1.00 80.58  ? 111 TYR B O   1 
ATOM 2873 C CB  . TYR B 2 121 ? 103.828 96.352  150.703 1.00 77.14  ? 111 TYR B CB  1 
ATOM 2874 C CG  . TYR B 2 121 ? 102.734 95.434  151.188 1.00 83.94  ? 111 TYR B CG  1 
ATOM 2875 C CD1 . TYR B 2 121 ? 101.400 95.724  150.944 1.00 88.75  ? 111 TYR B CD1 1 
ATOM 2876 C CD2 . TYR B 2 121 ? 103.033 94.286  151.904 1.00 88.65  ? 111 TYR B CD2 1 
ATOM 2877 C CE1 . TYR B 2 121 ? 100.396 94.891  151.390 1.00 88.70  ? 111 TYR B CE1 1 
ATOM 2878 C CE2 . TYR B 2 121 ? 102.036 93.446  152.353 1.00 91.93  ? 111 TYR B CE2 1 
ATOM 2879 C CZ  . TYR B 2 121 ? 100.720 93.754  152.093 1.00 91.46  ? 111 TYR B CZ  1 
ATOM 2880 O OH  . TYR B 2 121 ? 99.722  92.921  152.539 1.00 92.41  ? 111 TYR B OH  1 
ATOM 2881 N N   . VAL B 2 122 ? 105.033 98.162  148.384 1.00 72.22  ? 112 VAL B N   1 
ATOM 2882 C CA  . VAL B 2 122 ? 105.929 99.282  148.135 1.00 69.85  ? 112 VAL B CA  1 
ATOM 2883 C C   . VAL B 2 122 ? 105.322 100.512 148.786 1.00 69.00  ? 112 VAL B C   1 
ATOM 2884 O O   . VAL B 2 122 ? 104.198 100.903 148.452 1.00 78.71  ? 112 VAL B O   1 
ATOM 2885 C CB  . VAL B 2 122 ? 106.163 99.527  146.638 1.00 74.52  ? 112 VAL B CB  1 
ATOM 2886 C CG1 . VAL B 2 122 ? 106.846 100.860 146.431 1.00 76.61  ? 112 VAL B CG1 1 
ATOM 2887 C CG2 . VAL B 2 122 ? 107.002 98.415  146.047 1.00 76.70  ? 112 VAL B CG2 1 
ATOM 2888 N N   . ALA B 2 123 ? 106.055 101.117 149.708 1.00 70.67  ? 113 ALA B N   1 
ATOM 2889 C CA  . ALA B 2 123 ? 105.615 102.329 150.375 1.00 74.34  ? 113 ALA B CA  1 
ATOM 2890 C C   . ALA B 2 123 ? 106.035 103.539 149.558 1.00 76.31  ? 113 ALA B C   1 
ATOM 2891 O O   . ALA B 2 123 ? 107.031 103.498 148.833 1.00 82.03  ? 113 ALA B O   1 
ATOM 2892 C CB  . ALA B 2 123 ? 106.192 102.420 151.785 1.00 81.58  ? 113 ALA B CB  1 
ATOM 2893 N N   . CYS B 2 124 ? 105.264 104.610 149.673 1.00 80.11  ? 114 CYS B N   1 
ATOM 2894 C CA  . CYS B 2 124 ? 105.493 105.819 148.903 1.00 80.70  ? 114 CYS B CA  1 
ATOM 2895 C C   . CYS B 2 124 ? 104.954 107.009 149.678 1.00 86.31  ? 114 CYS B C   1 
ATOM 2896 O O   . CYS B 2 124 ? 103.863 106.951 150.251 1.00 97.02  ? 114 CYS B O   1 
ATOM 2897 C CB  . CYS B 2 124 ? 104.824 105.722 147.532 1.00 89.91  ? 114 CYS B CB  1 
ATOM 2898 S SG  . CYS B 2 124 ? 104.653 107.278 146.673 1.00 118.71 ? 114 CYS B SG  1 
ATOM 2899 N N   . GLY B 2 125 ? 105.723 108.087 149.689 1.00 79.00  ? 115 GLY B N   1 
ATOM 2900 C CA  . GLY B 2 125 ? 105.340 109.262 150.445 1.00 83.67  ? 115 GLY B CA  1 
ATOM 2901 C C   . GLY B 2 125 ? 106.064 110.484 149.938 1.00 87.03  ? 115 GLY B C   1 
ATOM 2902 O O   . GLY B 2 125 ? 107.064 110.386 149.220 1.00 92.03  ? 115 GLY B O   1 
ATOM 2903 N N   . GLY B 2 126 ? 105.546 111.643 150.326 1.00 86.63  ? 116 GLY B N   1 
ATOM 2904 C CA  . GLY B 2 126 ? 106.116 112.893 149.876 1.00 85.15  ? 116 GLY B CA  1 
ATOM 2905 C C   . GLY B 2 126 ? 105.526 114.114 150.546 1.00 85.59  ? 116 GLY B C   1 
ATOM 2906 O O   . GLY B 2 126 ? 105.292 114.121 151.757 1.00 90.54  ? 116 GLY B O   1 
ATOM 2907 N N   . LEU B 2 127 ? 105.273 115.155 149.760 1.00 81.14  ? 117 LEU B N   1 
ATOM 2908 C CA  . LEU B 2 127 ? 104.826 116.433 150.290 1.00 81.03  ? 117 LEU B CA  1 
ATOM 2909 C C   . LEU B 2 127 ? 103.328 116.482 150.545 1.00 86.28  ? 117 LEU B C   1 
ATOM 2910 O O   . LEU B 2 127 ? 102.835 117.499 151.042 1.00 94.22  ? 117 LEU B O   1 
ATOM 2911 C CB  . LEU B 2 127 ? 105.219 117.559 149.333 1.00 80.16  ? 117 LEU B CB  1 
ATOM 2912 C CG  . LEU B 2 127 ? 106.444 118.401 149.691 1.00 81.60  ? 117 LEU B CG  1 
ATOM 2913 C CD1 . LEU B 2 127 ? 107.659 117.529 149.952 1.00 86.29  ? 117 LEU B CD1 1 
ATOM 2914 C CD2 . LEU B 2 127 ? 106.732 119.394 148.585 1.00 77.03  ? 117 LEU B CD2 1 
ATOM 2915 N N   . ASP B 2 128 ? 102.595 115.422 150.223 1.00 79.82  ? 118 ASP B N   1 
ATOM 2916 C CA  . ASP B 2 128 ? 101.157 115.374 150.444 1.00 83.89  ? 118 ASP B CA  1 
ATOM 2917 C C   . ASP B 2 128 ? 100.780 114.934 151.851 1.00 87.39  ? 118 ASP B C   1 
ATOM 2918 O O   . ASP B 2 128 ? 99.591  114.711 152.107 1.00 93.39  ? 118 ASP B O   1 
ATOM 2919 C CB  . ASP B 2 128 ? 100.496 114.468 149.399 1.00 91.17  ? 118 ASP B CB  1 
ATOM 2920 C CG  . ASP B 2 128 ? 100.885 112.997 149.538 1.00 98.32  ? 118 ASP B CG  1 
ATOM 2921 O OD1 . ASP B 2 128 ? 101.855 112.665 150.254 1.00 100.58 ? 118 ASP B OD1 1 
ATOM 2922 O OD2 . ASP B 2 128 ? 100.202 112.157 148.916 1.00 97.23  ? 118 ASP B OD2 1 
ATOM 2923 N N   . ASN B 2 129 ? 101.775 114.779 152.730 1.00 84.25  ? 119 ASN B N   1 
ATOM 2924 C CA  . ASN B 2 129 ? 101.609 114.398 154.135 1.00 87.22  ? 119 ASN B CA  1 
ATOM 2925 C C   . ASN B 2 129 ? 100.958 113.025 154.275 1.00 92.34  ? 119 ASN B C   1 
ATOM 2926 O O   . ASN B 2 129 ? 100.281 112.744 155.266 1.00 95.22  ? 119 ASN B O   1 
ATOM 2927 C CB  . ASN B 2 129 ? 100.810 115.447 154.913 1.00 87.18  ? 119 ASN B CB  1 
ATOM 2928 C CG  . ASN B 2 129 ? 101.539 116.761 155.021 1.00 87.78  ? 119 ASN B CG  1 
ATOM 2929 O OD1 . ASN B 2 129 ? 102.726 116.843 154.734 1.00 86.35  ? 119 ASN B OD1 1 
ATOM 2930 N ND2 . ASN B 2 129 ? 100.831 117.801 155.440 1.00 93.60  ? 119 ASN B ND2 1 
ATOM 2931 N N   . ILE B 2 130 ? 101.160 112.161 153.285 1.00 89.60  ? 120 ILE B N   1 
ATOM 2932 C CA  . ILE B 2 130 ? 100.463 110.886 153.192 1.00 87.57  ? 120 ILE B CA  1 
ATOM 2933 C C   . ILE B 2 130 ? 101.467 109.823 152.774 1.00 89.84  ? 120 ILE B C   1 
ATOM 2934 O O   . ILE B 2 130 ? 102.207 110.011 151.803 1.00 90.19  ? 120 ILE B O   1 
ATOM 2935 C CB  . ILE B 2 130 ? 99.289  110.972 152.194 1.00 86.33  ? 120 ILE B CB  1 
ATOM 2936 C CG1 . ILE B 2 130 ? 98.072  111.611 152.861 1.00 84.59  ? 120 ILE B CG1 1 
ATOM 2937 C CG2 . ILE B 2 130 ? 98.930  109.609 151.626 1.00 87.78  ? 120 ILE B CG2 1 
ATOM 2938 C CD1 . ILE B 2 130 ? 97.067  112.173 151.883 1.00 92.76  ? 120 ILE B CD1 1 
ATOM 2939 N N   . CYS B 2 131 ? 101.505 108.714 153.510 1.00 89.24  ? 121 CYS B N   1 
ATOM 2940 C CA  . CYS B 2 131 ? 102.350 107.574 153.167 1.00 85.00  ? 121 CYS B CA  1 
ATOM 2941 C C   . CYS B 2 131 ? 101.468 106.527 152.503 1.00 82.12  ? 121 CYS B C   1 
ATOM 2942 O O   . CYS B 2 131 ? 100.780 105.759 153.179 1.00 85.93  ? 121 CYS B O   1 
ATOM 2943 C CB  . CYS B 2 131 ? 103.045 107.016 154.401 1.00 89.43  ? 121 CYS B CB  1 
ATOM 2944 S SG  . CYS B 2 131 ? 104.513 106.039 154.032 1.00 102.68 ? 121 CYS B SG  1 
ATOM 2945 N N   . SER B 2 132 ? 101.490 106.496 151.175 1.00 82.37  ? 122 SER B N   1 
ATOM 2946 C CA  . SER B 2 132 ? 100.672 105.568 150.411 1.00 84.59  ? 122 SER B CA  1 
ATOM 2947 C C   . SER B 2 132 ? 101.425 104.261 150.218 1.00 81.98  ? 122 SER B C   1 
ATOM 2948 O O   . SER B 2 132 ? 102.555 104.256 149.721 1.00 86.40  ? 122 SER B O   1 
ATOM 2949 C CB  . SER B 2 132 ? 100.297 106.167 149.056 1.00 86.25  ? 122 SER B CB  1 
ATOM 2950 O OG  . SER B 2 132 ? 99.897  107.519 149.187 1.00 84.82  ? 122 SER B OG  1 
ATOM 2951 N N   . ILE B 2 133 ? 100.797 103.158 150.614 1.00 75.88  ? 123 ILE B N   1 
ATOM 2952 C CA  . ILE B 2 133 ? 101.389 101.829 150.528 1.00 71.43  ? 123 ILE B CA  1 
ATOM 2953 C C   . ILE B 2 133 ? 100.574 101.003 149.547 1.00 77.70  ? 123 ILE B C   1 
ATOM 2954 O O   . ILE B 2 133 ? 99.353  100.880 149.693 1.00 87.02  ? 123 ILE B O   1 
ATOM 2955 C CB  . ILE B 2 133 ? 101.455 101.156 151.908 1.00 69.45  ? 123 ILE B CB  1 
ATOM 2956 C CG1 . ILE B 2 133 ? 101.894 102.183 152.952 1.00 82.22  ? 123 ILE B CG1 1 
ATOM 2957 C CG2 . ILE B 2 133 ? 102.393 99.966  151.870 1.00 72.38  ? 123 ILE B CG2 1 
ATOM 2958 C CD1 . ILE B 2 133 ? 102.243 101.618 154.291 1.00 84.32  ? 123 ILE B CD1 1 
ATOM 2959 N N   . TYR B 2 134 ? 101.248 100.440 148.552 1.00 77.91  ? 124 TYR B N   1 
ATOM 2960 C CA  . TYR B 2 134 ? 100.610 99.709  147.471 1.00 78.13  ? 124 TYR B CA  1 
ATOM 2961 C C   . TYR B 2 134 ? 100.787 98.210  147.667 1.00 89.61  ? 124 TYR B C   1 
ATOM 2962 O O   . TYR B 2 134 ? 101.605 97.758  148.471 1.00 94.63  ? 124 TYR B O   1 
ATOM 2963 C CB  . TYR B 2 134 ? 101.186 100.131 146.117 1.00 75.03  ? 124 TYR B CB  1 
ATOM 2964 C CG  . TYR B 2 134 ? 100.893 101.564 145.748 1.00 75.49  ? 124 TYR B CG  1 
ATOM 2965 C CD1 . TYR B 2 134 ? 101.724 102.591 146.163 1.00 73.64  ? 124 TYR B CD1 1 
ATOM 2966 C CD2 . TYR B 2 134 ? 99.784  101.889 144.983 1.00 84.59  ? 124 TYR B CD2 1 
ATOM 2967 C CE1 . TYR B 2 134 ? 101.459 103.900 145.829 1.00 78.14  ? 124 TYR B CE1 1 
ATOM 2968 C CE2 . TYR B 2 134 ? 99.511  103.195 144.646 1.00 84.67  ? 124 TYR B CE2 1 
ATOM 2969 C CZ  . TYR B 2 134 ? 100.351 104.194 145.070 1.00 81.09  ? 124 TYR B CZ  1 
ATOM 2970 O OH  . TYR B 2 134 ? 100.080 105.498 144.733 1.00 80.05  ? 124 TYR B OH  1 
ATOM 2971 N N   . ASN B 2 135 ? 100.005 97.438  146.918 1.00 95.50  ? 125 ASN B N   1 
ATOM 2972 C CA  . ASN B 2 135 ? 100.044 95.981  146.965 1.00 94.44  ? 125 ASN B CA  1 
ATOM 2973 C C   . ASN B 2 135 ? 100.597 95.452  145.650 1.00 94.40  ? 125 ASN B C   1 
ATOM 2974 O O   . ASN B 2 135 ? 100.117 95.829  144.576 1.00 97.97  ? 125 ASN B O   1 
ATOM 2975 C CB  . ASN B 2 135 ? 98.656  95.404  147.231 1.00 96.89  ? 125 ASN B CB  1 
ATOM 2976 C CG  . ASN B 2 135 ? 98.697  94.168  148.097 1.00 99.82  ? 125 ASN B CG  1 
ATOM 2977 O OD1 . ASN B 2 135 ? 99.680  93.430  148.095 1.00 96.82  ? 125 ASN B OD1 1 
ATOM 2978 N ND2 . ASN B 2 135 ? 97.626  93.932  148.842 1.00 106.02 ? 125 ASN B ND2 1 
ATOM 2979 N N   . LEU B 2 136 ? 101.596 94.577  145.736 1.00 95.44  ? 126 LEU B N   1 
ATOM 2980 C CA  . LEU B 2 136 ? 102.204 93.987  144.552 1.00 95.47  ? 126 LEU B CA  1 
ATOM 2981 C C   . LEU B 2 136 ? 101.700 92.584  144.255 1.00 96.09  ? 126 LEU B C   1 
ATOM 2982 O O   . LEU B 2 136 ? 101.854 92.110  143.125 1.00 95.26  ? 126 LEU B O   1 
ATOM 2983 C CB  . LEU B 2 136 ? 103.724 93.935  144.710 1.00 95.56  ? 126 LEU B CB  1 
ATOM 2984 C CG  . LEU B 2 136 ? 104.447 95.257  144.934 1.00 93.61  ? 126 LEU B CG  1 
ATOM 2985 C CD1 . LEU B 2 136 ? 105.943 95.022  144.920 1.00 93.36  ? 126 LEU B CD1 1 
ATOM 2986 C CD2 . LEU B 2 136 ? 104.044 96.269  143.880 1.00 87.64  ? 126 LEU B CD2 1 
ATOM 2987 N N   . LYS B 2 137 ? 101.112 91.912  145.234 1.00 98.06  ? 127 LYS B N   1 
ATOM 2988 C CA  . LYS B 2 137 ? 100.658 90.542  145.074 1.00 104.55 ? 127 LYS B CA  1 
ATOM 2989 C C   . LYS B 2 137 ? 99.225  90.528  144.543 1.00 109.37 ? 127 LYS B C   1 
ATOM 2990 O O   . LYS B 2 137 ? 98.728  91.526  144.013 1.00 106.04 ? 127 LYS B O   1 
ATOM 2991 C CB  . LYS B 2 137 ? 100.793 89.788  146.395 1.00 103.83 ? 127 LYS B CB  1 
ATOM 2992 C CG  . LYS B 2 137 ? 102.230 89.438  146.766 1.00 103.54 ? 127 LYS B CG  1 
ATOM 2993 C CD  . LYS B 2 137 ? 102.981 88.837  145.583 1.00 104.20 ? 127 LYS B CD  1 
ATOM 2994 C CE  . LYS B 2 137 ? 104.217 88.073  146.031 1.00 104.65 ? 127 LYS B CE  1 
ATOM 2995 N NZ  . LYS B 2 137 ? 105.254 88.977  146.603 1.00 101.09 ? 127 LYS B NZ  1 
ATOM 2996 N N   . THR B 2 138 ? 98.577  89.359  144.643 1.00 119.68 ? 128 THR B N   1 
ATOM 2997 C CA  . THR B 2 138 ? 97.186  89.067  144.279 1.00 126.87 ? 128 THR B CA  1 
ATOM 2998 C C   . THR B 2 138 ? 96.922  89.176  142.778 1.00 128.13 ? 128 THR B C   1 
ATOM 2999 O O   . THR B 2 138 ? 97.711  89.761  142.028 1.00 127.52 ? 128 THR B O   1 
ATOM 3000 C CB  . THR B 2 138 ? 96.193  89.942  145.062 1.00 127.85 ? 128 THR B CB  1 
ATOM 3001 O OG1 . THR B 2 138 ? 96.304  91.309  144.644 1.00 129.19 ? 128 THR B OG1 1 
ATOM 3002 C CG2 . THR B 2 138 ? 96.441  89.839  146.564 1.00 118.39 ? 128 THR B CG2 1 
ATOM 3003 N N   . ARG B 2 139 ? 95.814  88.589  142.328 1.00 127.24 ? 129 ARG B N   1 
ATOM 3004 C CA  . ARG B 2 139 ? 95.587  88.324  140.915 1.00 129.79 ? 129 ARG B CA  1 
ATOM 3005 C C   . ARG B 2 139 ? 94.714  89.363  140.220 1.00 130.73 ? 129 ARG B C   1 
ATOM 3006 O O   . ARG B 2 139 ? 94.360  89.163  139.053 1.00 135.10 ? 129 ARG B O   1 
ATOM 3007 C CB  . ARG B 2 139 ? 94.964  86.936  140.740 1.00 124.83 ? 129 ARG B CB  1 
ATOM 3008 N N   . GLU B 2 140 ? 94.351  90.455  140.887 1.00 127.97 ? 130 GLU B N   1 
ATOM 3009 C CA  . GLU B 2 140 ? 93.560  91.457  140.190 1.00 131.23 ? 130 GLU B CA  1 
ATOM 3010 C C   . GLU B 2 140 ? 94.451  92.285  139.267 1.00 134.28 ? 130 GLU B C   1 
ATOM 3011 O O   . GLU B 2 140 ? 95.683  92.227  139.325 1.00 130.52 ? 130 GLU B O   1 
ATOM 3012 C CB  . GLU B 2 140 ? 92.822  92.367  141.171 1.00 132.37 ? 130 GLU B CB  1 
ATOM 3013 C CG  . GLU B 2 140 ? 93.665  93.488  141.750 1.00 134.74 ? 130 GLU B CG  1 
ATOM 3014 C CD  . GLU B 2 140 ? 94.352  93.088  143.030 1.00 131.86 ? 130 GLU B CD  1 
ATOM 3015 O OE1 . GLU B 2 140 ? 94.154  91.937  143.466 1.00 131.92 ? 130 GLU B OE1 1 
ATOM 3016 O OE2 . GLU B 2 140 ? 95.089  93.919  143.601 1.00 127.92 ? 130 GLU B OE2 1 
ATOM 3017 N N   . GLY B 2 141 ? 93.806  93.059  138.398 1.00 136.07 ? 131 GLY B N   1 
ATOM 3018 C CA  . GLY B 2 141 ? 94.543  93.849  137.429 1.00 134.52 ? 131 GLY B CA  1 
ATOM 3019 C C   . GLY B 2 141 ? 95.281  95.004  138.084 1.00 135.22 ? 131 GLY B C   1 
ATOM 3020 O O   . GLY B 2 141 ? 94.814  95.596  139.059 1.00 131.96 ? 131 GLY B O   1 
ATOM 3021 N N   . ASN B 2 142 ? 96.465  95.304  137.537 1.00 136.74 ? 132 ASN B N   1 
ATOM 3022 C CA  . ASN B 2 142 ? 97.319  96.428  137.918 1.00 129.75 ? 132 ASN B CA  1 
ATOM 3023 C C   . ASN B 2 142 ? 97.735  96.388  139.385 1.00 122.41 ? 132 ASN B C   1 
ATOM 3024 O O   . ASN B 2 142 ? 97.663  95.340  140.036 1.00 124.82 ? 132 ASN B O   1 
ATOM 3025 C CB  . ASN B 2 142 ? 96.631  97.761  137.602 1.00 132.71 ? 132 ASN B CB  1 
ATOM 3026 C CG  . ASN B 2 142 ? 96.539  98.029  136.112 1.00 144.22 ? 132 ASN B CG  1 
ATOM 3027 O OD1 . ASN B 2 142 ? 97.314  97.489  135.323 1.00 147.74 ? 132 ASN B OD1 1 
ATOM 3028 N ND2 . ASN B 2 142 ? 95.587  98.868  135.720 1.00 143.82 ? 132 ASN B ND2 1 
ATOM 3029 N N   . VAL B 2 143 ? 98.185  97.529  139.903 1.00 116.65 ? 133 VAL B N   1 
ATOM 3030 C CA  . VAL B 2 143 ? 98.635  97.664  141.282 1.00 104.15 ? 133 VAL B CA  1 
ATOM 3031 C C   . VAL B 2 143 ? 97.682  98.607  141.999 1.00 96.36  ? 133 VAL B C   1 
ATOM 3032 O O   . VAL B 2 143 ? 97.470  99.740  141.553 1.00 98.35  ? 133 VAL B O   1 
ATOM 3033 C CB  . VAL B 2 143 ? 100.082 98.181  141.356 1.00 98.28  ? 133 VAL B CB  1 
ATOM 3034 C CG1 . VAL B 2 143 ? 100.436 98.585  142.776 1.00 93.19  ? 133 VAL B CG1 1 
ATOM 3035 C CG2 . VAL B 2 143 ? 101.043 97.125  140.843 1.00 92.28  ? 133 VAL B CG2 1 
ATOM 3036 N N   . ARG B 2 144 ? 97.111  98.139  143.103 1.00 93.22  ? 134 ARG B N   1 
ATOM 3037 C CA  . ARG B 2 144 ? 96.091  98.869  143.834 1.00 96.55  ? 134 ARG B CA  1 
ATOM 3038 C C   . ARG B 2 144 ? 96.619  99.253  145.211 1.00 99.99  ? 134 ARG B C   1 
ATOM 3039 O O   . ARG B 2 144 ? 97.233  98.442  145.910 1.00 104.64 ? 134 ARG B O   1 
ATOM 3040 C CB  . ARG B 2 144 ? 94.810  98.027  143.954 1.00 93.73  ? 134 ARG B CB  1 
ATOM 3041 C CG  . ARG B 2 144 ? 93.906  98.377  145.125 1.00 100.55 ? 134 ARG B CG  1 
ATOM 3042 C CD  . ARG B 2 144 ? 93.104  97.171  145.602 1.00 105.33 ? 134 ARG B CD  1 
ATOM 3043 N NE  . ARG B 2 144 ? 93.856  95.920  145.570 1.00 114.85 ? 134 ARG B NE  1 
ATOM 3044 C CZ  . ARG B 2 144 ? 94.813  95.584  146.427 1.00 119.20 ? 134 ARG B CZ  1 
ATOM 3045 N NH1 . ARG B 2 144 ? 95.148  96.370  147.437 1.00 111.00 ? 134 ARG B NH1 1 
ATOM 3046 N NH2 . ARG B 2 144 ? 95.442  94.422  146.272 1.00 120.40 ? 134 ARG B NH2 1 
ATOM 3047 N N   . VAL B 2 145 ? 96.387  100.509 145.585 1.00 93.08  ? 135 VAL B N   1 
ATOM 3048 C CA  . VAL B 2 145 ? 96.806  101.011 146.889 1.00 84.83  ? 135 VAL B CA  1 
ATOM 3049 C C   . VAL B 2 145 ? 95.974  100.346 147.980 1.00 87.98  ? 135 VAL B C   1 
ATOM 3050 O O   . VAL B 2 145 ? 94.746  100.240 147.875 1.00 92.28  ? 135 VAL B O   1 
ATOM 3051 C CB  . VAL B 2 145 ? 96.718  102.549 146.936 1.00 79.89  ? 135 VAL B CB  1 
ATOM 3052 C CG1 . VAL B 2 145 ? 95.331  103.060 146.558 1.00 80.75  ? 135 VAL B CG1 1 
ATOM 3053 C CG2 . VAL B 2 145 ? 97.123  103.069 148.304 1.00 81.95  ? 135 VAL B CG2 1 
ATOM 3054 N N   . SER B 2 146 ? 96.653  99.834  149.005 1.00 85.82  ? 136 SER B N   1 
ATOM 3055 C CA  . SER B 2 146 ? 95.991  99.097  150.074 1.00 87.80  ? 136 SER B CA  1 
ATOM 3056 C C   . SER B 2 146 ? 95.543  100.021 151.201 1.00 86.59  ? 136 SER B C   1 
ATOM 3057 O O   . SER B 2 146 ? 94.349  100.106 151.505 1.00 89.55  ? 136 SER B O   1 
ATOM 3058 C CB  . SER B 2 146 ? 96.922  98.006  150.613 1.00 97.23  ? 136 SER B CB  1 
ATOM 3059 O OG  . SER B 2 146 ? 97.720  98.497  151.675 1.00 105.17 ? 136 SER B OG  1 
ATOM 3060 N N   . ARG B 2 147 ? 96.485  100.720 151.826 1.00 84.96  ? 137 ARG B N   1 
ATOM 3061 C CA  . ARG B 2 147 ? 96.176  101.633 152.913 1.00 86.59  ? 137 ARG B CA  1 
ATOM 3062 C C   . ARG B 2 147 ? 96.762  103.003 152.617 1.00 87.02  ? 137 ARG B C   1 
ATOM 3063 O O   . ARG B 2 147 ? 97.529  103.190 151.671 1.00 87.67  ? 137 ARG B O   1 
ATOM 3064 C CB  . ARG B 2 147 ? 96.698  101.115 154.261 1.00 88.47  ? 137 ARG B CB  1 
ATOM 3065 C CG  . ARG B 2 147 ? 96.211  99.722  154.664 1.00 92.75  ? 137 ARG B CG  1 
ATOM 3066 C CD  . ARG B 2 147 ? 94.687  99.578  154.790 1.00 93.09  ? 137 ARG B CD  1 
ATOM 3067 N NE  . ARG B 2 147 ? 93.990  100.798 155.185 1.00 98.70  ? 137 ARG B NE  1 
ATOM 3068 C CZ  . ARG B 2 147 ? 93.914  101.254 156.427 1.00 104.65 ? 137 ARG B CZ  1 
ATOM 3069 N NH1 . ARG B 2 147 ? 94.473  100.608 157.437 1.00 108.82 ? 137 ARG B NH1 1 
ATOM 3070 N NH2 . ARG B 2 147 ? 93.256  102.385 156.663 1.00 101.46 ? 137 ARG B NH2 1 
ATOM 3071 N N   . GLU B 2 148 ? 96.387  103.967 153.451 1.00 88.87  ? 138 GLU B N   1 
ATOM 3072 C CA  . GLU B 2 148 ? 96.812  105.353 153.296 1.00 89.21  ? 138 GLU B CA  1 
ATOM 3073 C C   . GLU B 2 148 ? 96.914  105.954 154.690 1.00 95.75  ? 138 GLU B C   1 
ATOM 3074 O O   . GLU B 2 148 ? 95.901  106.093 155.383 1.00 100.68 ? 138 GLU B O   1 
ATOM 3075 C CB  . GLU B 2 148 ? 95.830  106.129 152.420 1.00 95.14  ? 138 GLU B CB  1 
ATOM 3076 C CG  . GLU B 2 148 ? 95.960  107.633 152.486 1.00 100.29 ? 138 GLU B CG  1 
ATOM 3077 C CD  . GLU B 2 148 ? 95.006  108.336 151.540 1.00 108.87 ? 138 GLU B CD  1 
ATOM 3078 O OE1 . GLU B 2 148 ? 94.253  107.638 150.828 1.00 108.51 ? 138 GLU B OE1 1 
ATOM 3079 O OE2 . GLU B 2 148 ? 95.005  109.584 151.508 1.00 111.64 ? 138 GLU B OE2 1 
ATOM 3080 N N   . LEU B 2 149 ? 98.129  106.298 155.104 1.00 92.32  ? 139 LEU B N   1 
ATOM 3081 C CA  . LEU B 2 149 ? 98.390  106.783 156.452 1.00 89.58  ? 139 LEU B CA  1 
ATOM 3082 C C   . LEU B 2 149 ? 98.530  108.298 156.428 1.00 90.31  ? 139 LEU B C   1 
ATOM 3083 O O   . LEU B 2 149 ? 99.354  108.838 155.683 1.00 94.28  ? 139 LEU B O   1 
ATOM 3084 C CB  . LEU B 2 149 ? 99.650  106.135 157.021 1.00 88.36  ? 139 LEU B CB  1 
ATOM 3085 C CG  . LEU B 2 149 ? 99.847  104.669 156.646 1.00 89.15  ? 139 LEU B CG  1 
ATOM 3086 C CD1 . LEU B 2 149 ? 101.277 104.239 156.908 1.00 88.30  ? 139 LEU B CD1 1 
ATOM 3087 C CD2 . LEU B 2 149 ? 98.873  103.791 157.412 1.00 93.53  ? 139 LEU B CD2 1 
ATOM 3088 N N   . ALA B 2 150 ? 97.728  108.979 157.248 1.00 84.88  ? 140 ALA B N   1 
ATOM 3089 C CA  . ALA B 2 150 ? 97.766  110.437 157.327 1.00 88.75  ? 140 ALA B CA  1 
ATOM 3090 C C   . ALA B 2 150 ? 97.444  110.824 158.768 1.00 95.05  ? 140 ALA B C   1 
ATOM 3091 O O   . ALA B 2 150 ? 96.271  110.930 159.136 1.00 100.49 ? 140 ALA B O   1 
ATOM 3092 C CB  . ALA B 2 150 ? 96.787  111.067 156.347 1.00 91.51  ? 140 ALA B CB  1 
ATOM 3093 N N   . GLY B 2 151 ? 98.484  111.028 159.570 1.00 94.19  ? 141 GLY B N   1 
ATOM 3094 C CA  . GLY B 2 151 ? 98.301  111.345 160.973 1.00 98.90  ? 141 GLY B CA  1 
ATOM 3095 C C   . GLY B 2 151 ? 99.315  112.326 161.521 1.00 102.44 ? 141 GLY B C   1 
ATOM 3096 O O   . GLY B 2 151 ? 99.532  112.390 162.734 1.00 111.05 ? 141 GLY B O   1 
ATOM 3097 N N   . HIS B 2 152 ? 99.944  113.095 160.640 1.00 96.71  ? 142 HIS B N   1 
ATOM 3098 C CA  . HIS B 2 152 ? 100.986 114.030 161.033 1.00 100.76 ? 142 HIS B CA  1 
ATOM 3099 C C   . HIS B 2 152 ? 100.857 115.320 160.236 1.00 98.41  ? 142 HIS B C   1 
ATOM 3100 O O   . HIS B 2 152 ? 100.183 115.381 159.205 1.00 96.30  ? 142 HIS B O   1 
ATOM 3101 C CB  . HIS B 2 152 ? 102.378 113.397 160.890 1.00 96.63  ? 142 HIS B CB  1 
ATOM 3102 C CG  . HIS B 2 152 ? 102.664 112.841 159.530 1.00 96.92  ? 142 HIS B CG  1 
ATOM 3103 N ND1 . HIS B 2 152 ? 103.719 111.988 159.292 1.00 97.49  ? 142 HIS B ND1 1 
ATOM 3104 C CD2 . HIS B 2 152 ? 102.027 112.990 158.344 1.00 97.71  ? 142 HIS B CD2 1 
ATOM 3105 C CE1 . HIS B 2 152 ? 103.722 111.640 158.018 1.00 101.11 ? 142 HIS B CE1 1 
ATOM 3106 N NE2 . HIS B 2 152 ? 102.707 112.236 157.421 1.00 100.83 ? 142 HIS B NE2 1 
ATOM 3107 N N   . THR B 2 153 ? 101.519 116.362 160.733 1.00 94.91  ? 143 THR B N   1 
ATOM 3108 C CA  . THR B 2 153 ? 101.376 117.720 160.224 1.00 89.72  ? 143 THR B CA  1 
ATOM 3109 C C   . THR B 2 153 ? 102.661 118.206 159.567 1.00 86.20  ? 143 THR B C   1 
ATOM 3110 O O   . THR B 2 153 ? 103.102 119.333 159.789 1.00 91.45  ? 143 THR B O   1 
ATOM 3111 C CB  . THR B 2 153 ? 100.972 118.683 161.337 1.00 94.21  ? 143 THR B CB  1 
ATOM 3112 O OG1 . THR B 2 153 ? 102.148 119.187 161.981 1.00 100.00 ? 143 THR B OG1 1 
ATOM 3113 C CG2 . THR B 2 153 ? 100.092 117.990 162.372 1.00 86.41  ? 143 THR B CG2 1 
ATOM 3114 N N   . GLY B 2 154 ? 103.282 117.359 158.760 1.00 83.66  ? 144 GLY B N   1 
ATOM 3115 C CA  . GLY B 2 154 ? 104.496 117.756 158.079 1.00 86.39  ? 144 GLY B CA  1 
ATOM 3116 C C   . GLY B 2 154 ? 104.810 116.823 156.936 1.00 88.23  ? 144 GLY B C   1 
ATOM 3117 O O   . GLY B 2 154 ? 104.308 115.696 156.868 1.00 95.57  ? 144 GLY B O   1 
ATOM 3118 N N   . TYR B 2 155 ? 105.652 117.314 156.036 1.00 83.35  ? 145 TYR B N   1 
ATOM 3119 C CA  . TYR B 2 155 ? 106.036 116.575 154.841 1.00 77.14  ? 145 TYR B CA  1 
ATOM 3120 C C   . TYR B 2 155 ? 106.853 115.331 155.162 1.00 80.91  ? 145 TYR B C   1 
ATOM 3121 O O   . TYR B 2 155 ? 107.695 115.331 156.062 1.00 87.01  ? 145 TYR B O   1 
ATOM 3122 C CB  . TYR B 2 155 ? 106.800 117.500 153.891 1.00 75.86  ? 145 TYR B CB  1 
ATOM 3123 C CG  . TYR B 2 155 ? 108.208 117.863 154.320 1.00 80.01  ? 145 TYR B CG  1 
ATOM 3124 C CD1 . TYR B 2 155 ? 108.426 118.699 155.410 1.00 88.75  ? 145 TYR B CD1 1 
ATOM 3125 C CD2 . TYR B 2 155 ? 109.311 117.399 153.632 1.00 79.91  ? 145 TYR B CD2 1 
ATOM 3126 C CE1 . TYR B 2 155 ? 109.697 119.048 155.804 1.00 91.12  ? 145 TYR B CE1 1 
ATOM 3127 C CE2 . TYR B 2 155 ? 110.589 117.746 154.024 1.00 85.10  ? 145 TYR B CE2 1 
ATOM 3128 C CZ  . TYR B 2 155 ? 110.775 118.567 155.107 1.00 90.52  ? 145 TYR B CZ  1 
ATOM 3129 O OH  . TYR B 2 155 ? 112.046 118.911 155.498 1.00 96.20  ? 145 TYR B OH  1 
ATOM 3130 N N   . LEU B 2 156 ? 106.573 114.259 154.421 1.00 79.84  ? 146 LEU B N   1 
ATOM 3131 C CA  . LEU B 2 156 ? 107.327 113.022 154.556 1.00 77.29  ? 146 LEU B CA  1 
ATOM 3132 C C   . LEU B 2 156 ? 108.738 113.221 154.040 1.00 83.42  ? 146 LEU B C   1 
ATOM 3133 O O   . LEU B 2 156 ? 108.967 113.954 153.074 1.00 93.12  ? 146 LEU B O   1 
ATOM 3134 C CB  . LEU B 2 156 ? 106.682 111.885 153.769 1.00 84.59  ? 146 LEU B CB  1 
ATOM 3135 C CG  . LEU B 2 156 ? 105.572 111.016 154.351 1.00 91.46  ? 146 LEU B CG  1 
ATOM 3136 C CD1 . LEU B 2 156 ? 106.034 110.286 155.602 1.00 87.00  ? 146 LEU B CD1 1 
ATOM 3137 C CD2 . LEU B 2 156 ? 104.304 111.805 154.571 1.00 91.02  ? 146 LEU B CD2 1 
ATOM 3138 N N   . SER B 2 157 ? 109.688 112.562 154.682 1.00 82.33  ? 147 SER B N   1 
ATOM 3139 C CA  . SER B 2 157 ? 111.073 112.655 154.257 1.00 83.84  ? 147 SER B CA  1 
ATOM 3140 C C   . SER B 2 157 ? 111.672 111.305 153.907 1.00 85.49  ? 147 SER B C   1 
ATOM 3141 O O   . SER B 2 157 ? 112.262 111.157 152.830 1.00 89.49  ? 147 SER B O   1 
ATOM 3142 C CB  . SER B 2 157 ? 111.886 113.334 155.352 1.00 82.88  ? 147 SER B CB  1 
ATOM 3143 O OG  . SER B 2 157 ? 111.633 112.741 156.613 1.00 88.36  ? 147 SER B OG  1 
ATOM 3144 N N   . CYS B 2 158 ? 111.532 110.312 154.781 1.00 81.78  ? 148 CYS B N   1 
ATOM 3145 C CA  . CYS B 2 158 ? 112.003 108.969 154.483 1.00 83.33  ? 148 CYS B CA  1 
ATOM 3146 C C   . CYS B 2 158 ? 111.216 107.983 155.328 1.00 80.69  ? 148 CYS B C   1 
ATOM 3147 O O   . CYS B 2 158 ? 110.951 108.239 156.504 1.00 84.52  ? 148 CYS B O   1 
ATOM 3148 C CB  . CYS B 2 158 ? 113.506 108.823 154.739 1.00 86.24  ? 148 CYS B CB  1 
ATOM 3149 S SG  . CYS B 2 158 ? 114.052 107.147 155.082 1.00 94.33  ? 148 CYS B SG  1 
ATOM 3150 N N   . CYS B 2 159 ? 110.828 106.868 154.717 1.00 80.10  ? 149 CYS B N   1 
ATOM 3151 C CA  . CYS B 2 159 ? 110.063 105.834 155.394 1.00 76.95  ? 149 CYS B CA  1 
ATOM 3152 C C   . CYS B 2 159 ? 110.632 104.464 155.054 1.00 79.51  ? 149 CYS B C   1 
ATOM 3153 O O   . CYS B 2 159 ? 110.998 104.195 153.906 1.00 86.54  ? 149 CYS B O   1 
ATOM 3154 C CB  . CYS B 2 159 ? 108.572 105.941 155.033 1.00 78.49  ? 149 CYS B CB  1 
ATOM 3155 S SG  . CYS B 2 159 ? 107.974 104.931 153.672 1.00 96.73  ? 149 CYS B SG  1 
ATOM 3156 N N   . ARG B 2 160 ? 110.734 103.616 156.075 1.00 75.30  ? 150 ARG B N   1 
ATOM 3157 C CA  . ARG B 2 160 ? 111.303 102.280 155.974 1.00 76.07  ? 150 ARG B CA  1 
ATOM 3158 C C   . ARG B 2 160 ? 110.316 101.272 156.542 1.00 82.48  ? 150 ARG B C   1 
ATOM 3159 O O   . ARG B 2 160 ? 109.415 101.618 157.308 1.00 88.25  ? 150 ARG B O   1 
ATOM 3160 C CB  . ARG B 2 160 ? 112.642 102.163 156.718 1.00 78.91  ? 150 ARG B CB  1 
ATOM 3161 C CG  . ARG B 2 160 ? 113.814 102.966 156.158 1.00 75.18  ? 150 ARG B CG  1 
ATOM 3162 C CD  . ARG B 2 160 ? 113.845 102.955 154.644 1.00 73.94  ? 150 ARG B CD  1 
ATOM 3163 N NE  . ARG B 2 160 ? 114.970 103.705 154.102 1.00 76.48  ? 150 ARG B NE  1 
ATOM 3164 C CZ  . ARG B 2 160 ? 114.902 104.494 153.039 1.00 86.32  ? 150 ARG B CZ  1 
ATOM 3165 N NH1 . ARG B 2 160 ? 113.770 104.669 152.380 1.00 83.05  ? 150 ARG B NH1 1 
ATOM 3166 N NH2 . ARG B 2 160 ? 115.999 105.122 152.627 1.00 86.55  ? 150 ARG B NH2 1 
ATOM 3167 N N   . PHE B 2 161 ? 110.503 100.013 156.162 1.00 81.74  ? 151 PHE B N   1 
ATOM 3168 C CA  . PHE B 2 161 ? 109.614 98.925  156.546 1.00 82.17  ? 151 PHE B CA  1 
ATOM 3169 C C   . PHE B 2 161 ? 110.283 98.086  157.624 1.00 90.38  ? 151 PHE B C   1 
ATOM 3170 O O   . PHE B 2 161 ? 111.417 97.631  157.443 1.00 99.88  ? 151 PHE B O   1 
ATOM 3171 C CB  . PHE B 2 161 ? 109.282 98.044  155.343 1.00 81.15  ? 151 PHE B CB  1 
ATOM 3172 C CG  . PHE B 2 161 ? 107.944 98.319  154.730 1.00 81.88  ? 151 PHE B CG  1 
ATOM 3173 C CD1 . PHE B 2 161 ? 106.782 98.064  155.430 1.00 85.68  ? 151 PHE B CD1 1 
ATOM 3174 C CD2 . PHE B 2 161 ? 107.849 98.797  153.439 1.00 77.68  ? 151 PHE B CD2 1 
ATOM 3175 C CE1 . PHE B 2 161 ? 105.552 98.302  154.862 1.00 82.95  ? 151 PHE B CE1 1 
ATOM 3176 C CE2 . PHE B 2 161 ? 106.627 99.032  152.866 1.00 76.16  ? 151 PHE B CE2 1 
ATOM 3177 C CZ  . PHE B 2 161 ? 105.475 98.789  153.578 1.00 79.41  ? 151 PHE B CZ  1 
ATOM 3178 N N   . LEU B 2 162 ? 109.585 97.876  158.740 1.00 90.75  ? 152 LEU B N   1 
ATOM 3179 C CA  . LEU B 2 162 ? 110.027 96.873  159.705 1.00 97.13  ? 152 LEU B CA  1 
ATOM 3180 C C   . LEU B 2 162 ? 109.768 95.475  159.164 1.00 101.84 ? 152 LEU B C   1 
ATOM 3181 O O   . LEU B 2 162 ? 110.696 94.685  158.957 1.00 104.28 ? 152 LEU B O   1 
ATOM 3182 C CB  . LEU B 2 162 ? 109.307 97.065  161.040 1.00 97.25  ? 152 LEU B CB  1 
ATOM 3183 C CG  . LEU B 2 162 ? 109.923 97.874  162.183 1.00 96.49  ? 152 LEU B CG  1 
ATOM 3184 C CD1 . LEU B 2 162 ? 111.095 97.135  162.796 1.00 96.27  ? 152 LEU B CD1 1 
ATOM 3185 C CD2 . LEU B 2 162 ? 110.332 99.256  161.738 1.00 97.35  ? 152 LEU B CD2 1 
ATOM 3186 N N   . ASP B 2 163 ? 108.502 95.160  158.931 1.00 101.32 ? 153 ASP B N   1 
ATOM 3187 C CA  . ASP B 2 163 ? 108.061 93.964  158.234 1.00 100.72 ? 153 ASP B CA  1 
ATOM 3188 C C   . ASP B 2 163 ? 106.779 94.340  157.500 1.00 103.38 ? 153 ASP B C   1 
ATOM 3189 O O   . ASP B 2 163 ? 106.494 95.526  157.307 1.00 108.17 ? 153 ASP B O   1 
ATOM 3190 C CB  . ASP B 2 163 ? 107.888 92.792  159.214 1.00 104.01 ? 153 ASP B CB  1 
ATOM 3191 C CG  . ASP B 2 163 ? 107.180 93.198  160.485 1.00 110.78 ? 153 ASP B CG  1 
ATOM 3192 O OD1 . ASP B 2 163 ? 107.486 94.286  161.011 1.00 107.78 ? 153 ASP B OD1 1 
ATOM 3193 O OD2 . ASP B 2 163 ? 106.317 92.430  160.959 1.00 119.05 ? 153 ASP B OD2 1 
ATOM 3194 N N   . ASP B 2 164 ? 106.003 93.341  157.081 1.00 104.48 ? 154 ASP B N   1 
ATOM 3195 C CA  . ASP B 2 164 ? 104.742 93.635  156.410 1.00 104.46 ? 154 ASP B CA  1 
ATOM 3196 C C   . ASP B 2 164 ? 103.708 94.239  157.350 1.00 98.72  ? 154 ASP B C   1 
ATOM 3197 O O   . ASP B 2 164 ? 102.766 94.885  156.882 1.00 96.58  ? 154 ASP B O   1 
ATOM 3198 C CB  . ASP B 2 164 ? 104.173 92.368  155.771 1.00 109.87 ? 154 ASP B CB  1 
ATOM 3199 C CG  . ASP B 2 164 ? 104.637 92.178  154.341 1.00 111.82 ? 154 ASP B CG  1 
ATOM 3200 O OD1 . ASP B 2 164 ? 105.433 93.010  153.856 1.00 107.38 ? 154 ASP B OD1 1 
ATOM 3201 O OD2 . ASP B 2 164 ? 104.199 91.200  153.699 1.00 110.88 ? 154 ASP B OD2 1 
ATOM 3202 N N   . ASN B 2 165 ? 103.866 94.056  158.660 1.00 98.26  ? 155 ASN B N   1 
ATOM 3203 C CA  . ASN B 2 165 ? 102.840 94.486  159.601 1.00 100.69 ? 155 ASN B CA  1 
ATOM 3204 C C   . ASN B 2 165 ? 102.983 95.947  160.010 1.00 105.23 ? 155 ASN B C   1 
ATOM 3205 O O   . ASN B 2 165 ? 102.001 96.550  160.457 1.00 111.76 ? 155 ASN B O   1 
ATOM 3206 C CB  . ASN B 2 165 ? 102.872 93.594  160.842 1.00 108.85 ? 155 ASN B CB  1 
ATOM 3207 C CG  . ASN B 2 165 ? 101.491 93.330  161.403 1.00 114.84 ? 155 ASN B CG  1 
ATOM 3208 O OD1 . ASN B 2 165 ? 100.497 93.867  160.916 1.00 113.38 ? 155 ASN B OD1 1 
ATOM 3209 N ND2 . ASN B 2 165 ? 101.422 92.497  162.436 1.00 115.83 ? 155 ASN B ND2 1 
ATOM 3210 N N   . GLN B 2 166 ? 104.173 96.535  159.886 1.00 102.53 ? 156 GLN B N   1 
ATOM 3211 C CA  . GLN B 2 166 ? 104.375 97.889  160.384 1.00 96.18  ? 156 GLN B CA  1 
ATOM 3212 C C   . GLN B 2 166 ? 105.395 98.631  159.533 1.00 93.60  ? 156 GLN B C   1 
ATOM 3213 O O   . GLN B 2 166 ? 106.190 98.030  158.808 1.00 100.47 ? 156 GLN B O   1 
ATOM 3214 C CB  . GLN B 2 166 ? 104.810 97.891  161.852 1.00 92.76  ? 156 GLN B CB  1 
ATOM 3215 C CG  . GLN B 2 166 ? 105.555 96.654  162.294 1.00 97.70  ? 156 GLN B CG  1 
ATOM 3216 C CD  . GLN B 2 166 ? 105.576 96.509  163.797 1.00 99.64  ? 156 GLN B CD  1 
ATOM 3217 O OE1 . GLN B 2 166 ? 104.845 97.198  164.507 1.00 97.34  ? 156 GLN B OE1 1 
ATOM 3218 N NE2 . GLN B 2 166 ? 106.415 95.608  164.295 1.00 102.36 ? 156 GLN B NE2 1 
ATOM 3219 N N   . ILE B 2 167 ? 105.356 99.957  159.641 1.00 90.80  ? 157 ILE B N   1 
ATOM 3220 C CA  . ILE B 2 167 ? 106.200 100.858 158.865 1.00 88.58  ? 157 ILE B CA  1 
ATOM 3221 C C   . ILE B 2 167 ? 106.495 102.091 159.711 1.00 93.18  ? 157 ILE B C   1 
ATOM 3222 O O   . ILE B 2 167 ? 105.599 102.636 160.363 1.00 101.32 ? 157 ILE B O   1 
ATOM 3223 C CB  . ILE B 2 167 ? 105.522 101.231 157.527 1.00 84.01  ? 157 ILE B CB  1 
ATOM 3224 C CG1 . ILE B 2 167 ? 106.228 102.400 156.842 1.00 82.21  ? 157 ILE B CG1 1 
ATOM 3225 C CG2 . ILE B 2 167 ? 104.043 101.524 157.731 1.00 85.56  ? 157 ILE B CG2 1 
ATOM 3226 C CD1 . ILE B 2 167 ? 105.631 102.771 155.516 1.00 88.98  ? 157 ILE B CD1 1 
ATOM 3227 N N   . VAL B 2 168 ? 107.755 102.520 159.721 1.00 88.59  ? 158 VAL B N   1 
ATOM 3228 C CA  . VAL B 2 168 ? 108.184 103.691 160.476 1.00 87.71  ? 158 VAL B CA  1 
ATOM 3229 C C   . VAL B 2 168 ? 108.492 104.811 159.487 1.00 90.12  ? 158 VAL B C   1 
ATOM 3230 O O   . VAL B 2 168 ? 109.094 104.573 158.433 1.00 93.91  ? 158 VAL B O   1 
ATOM 3231 C CB  . VAL B 2 168 ? 109.385 103.364 161.385 1.00 89.30  ? 158 VAL B CB  1 
ATOM 3232 C CG1 . VAL B 2 168 ? 110.535 102.757 160.598 1.00 91.34  ? 158 VAL B CG1 1 
ATOM 3233 C CG2 . VAL B 2 168 ? 109.834 104.580 162.176 1.00 91.31  ? 158 VAL B CG2 1 
ATOM 3234 N N   . THR B 2 169 ? 108.018 106.016 159.791 1.00 90.99  ? 159 THR B N   1 
ATOM 3235 C CA  . THR B 2 169 ? 108.162 107.165 158.909 1.00 92.84  ? 159 THR B CA  1 
ATOM 3236 C C   . THR B 2 169 ? 108.877 108.298 159.629 1.00 93.85  ? 159 THR B C   1 
ATOM 3237 O O   . THR B 2 169 ? 108.637 108.544 160.814 1.00 97.16  ? 159 THR B O   1 
ATOM 3238 C CB  . THR B 2 169 ? 106.802 107.670 158.410 1.00 94.17  ? 159 THR B CB  1 
ATOM 3239 O OG1 . THR B 2 169 ? 106.061 108.217 159.506 1.00 93.03  ? 159 THR B OG1 1 
ATOM 3240 C CG2 . THR B 2 169 ? 106.000 106.547 157.765 1.00 92.99  ? 159 THR B CG2 1 
ATOM 3241 N N   . SER B 2 170 ? 109.753 108.985 158.903 1.00 92.60  ? 160 SER B N   1 
ATOM 3242 C CA  . SER B 2 170 ? 110.405 110.193 159.386 1.00 90.48  ? 160 SER B CA  1 
ATOM 3243 C C   . SER B 2 170 ? 109.699 111.391 158.769 1.00 88.56  ? 160 SER B C   1 
ATOM 3244 O O   . SER B 2 170 ? 109.628 111.510 157.542 1.00 90.60  ? 160 SER B O   1 
ATOM 3245 C CB  . SER B 2 170 ? 111.890 110.200 159.031 1.00 89.22  ? 160 SER B CB  1 
ATOM 3246 O OG  . SER B 2 170 ? 112.096 110.672 157.711 1.00 95.48  ? 160 SER B OG  1 
ATOM 3247 N N   . SER B 2 171 ? 109.188 112.274 159.614 1.00 90.36  ? 161 SER B N   1 
ATOM 3248 C CA  . SER B 2 171 ? 108.331 113.365 159.184 1.00 93.72  ? 161 SER B CA  1 
ATOM 3249 C C   . SER B 2 171 ? 109.085 114.685 159.235 1.00 92.34  ? 161 SER B C   1 
ATOM 3250 O O   . SER B 2 171 ? 110.218 114.771 159.712 1.00 95.10  ? 161 SER B O   1 
ATOM 3251 C CB  . SER B 2 171 ? 107.079 113.436 160.062 1.00 103.11 ? 161 SER B CB  1 
ATOM 3252 O OG  . SER B 2 171 ? 106.142 112.442 159.696 1.00 102.13 ? 161 SER B OG  1 
ATOM 3253 N N   . GLY B 2 172 ? 108.429 115.726 158.738 1.00 91.71  ? 162 GLY B N   1 
ATOM 3254 C CA  . GLY B 2 172 ? 108.980 117.062 158.714 1.00 87.76  ? 162 GLY B CA  1 
ATOM 3255 C C   . GLY B 2 172 ? 108.456 118.002 159.775 1.00 88.31  ? 162 GLY B C   1 
ATOM 3256 O O   . GLY B 2 172 ? 108.659 119.215 159.656 1.00 91.58  ? 162 GLY B O   1 
ATOM 3257 N N   . ASP B 2 173 ? 107.780 117.495 160.799 1.00 87.35  ? 163 ASP B N   1 
ATOM 3258 C CA  . ASP B 2 173 ? 107.296 118.313 161.902 1.00 89.54  ? 163 ASP B CA  1 
ATOM 3259 C C   . ASP B 2 173 ? 107.991 117.924 163.200 1.00 93.84  ? 163 ASP B C   1 
ATOM 3260 O O   . ASP B 2 173 ? 107.372 117.866 164.266 1.00 101.83 ? 163 ASP B O   1 
ATOM 3261 C CB  . ASP B 2 173 ? 105.778 118.216 162.036 1.00 96.54  ? 163 ASP B CB  1 
ATOM 3262 C CG  . ASP B 2 173 ? 105.299 116.801 162.270 1.00 104.29 ? 163 ASP B CG  1 
ATOM 3263 O OD1 . ASP B 2 173 ? 104.181 116.630 162.799 1.00 109.56 ? 163 ASP B OD1 1 
ATOM 3264 O OD2 . ASP B 2 173 ? 106.045 115.860 161.939 1.00 101.50 ? 163 ASP B OD2 1 
ATOM 3265 N N   . THR B 2 174 ? 109.299 117.659 163.099 1.00 92.68  ? 164 THR B N   1 
ATOM 3266 C CA  . THR B 2 174 ? 110.174 117.269 164.214 1.00 101.17 ? 164 THR B CA  1 
ATOM 3267 C C   . THR B 2 174 ? 109.681 116.014 164.931 1.00 104.41 ? 164 THR B C   1 
ATOM 3268 O O   . THR B 2 174 ? 109.890 115.857 166.135 1.00 103.67 ? 164 THR B O   1 
ATOM 3269 C CB  . THR B 2 174 ? 110.369 118.410 165.224 1.00 103.75 ? 164 THR B CB  1 
ATOM 3270 O OG1 . THR B 2 174 ? 109.192 118.547 166.030 1.00 113.57 ? 164 THR B OG1 1 
ATOM 3271 C CG2 . THR B 2 174 ? 110.652 119.727 164.515 1.00 99.66  ? 164 THR B CG2 1 
ATOM 3272 N N   . THR B 2 175 ? 109.024 115.109 164.208 1.00 102.61 ? 165 THR B N   1 
ATOM 3273 C CA  . THR B 2 175 ? 108.495 113.887 164.793 1.00 100.43 ? 165 THR B CA  1 
ATOM 3274 C C   . THR B 2 175 ? 108.843 112.690 163.922 1.00 98.20  ? 165 THR B C   1 
ATOM 3275 O O   . THR B 2 175 ? 109.015 112.808 162.707 1.00 98.75  ? 165 THR B O   1 
ATOM 3276 C CB  . THR B 2 175 ? 106.968 113.934 164.968 1.00 96.90  ? 165 THR B CB  1 
ATOM 3277 O OG1 . THR B 2 175 ? 106.351 114.249 163.715 1.00 99.69  ? 165 THR B OG1 1 
ATOM 3278 C CG2 . THR B 2 175 ? 106.560 114.963 166.015 1.00 95.73  ? 165 THR B CG2 1 
ATOM 3279 N N   . CYS B 2 176 ? 108.942 111.534 164.568 1.00 98.96  ? 166 CYS B N   1 
ATOM 3280 C CA  . CYS B 2 176 ? 109.030 110.243 163.904 1.00 93.32  ? 166 CYS B CA  1 
ATOM 3281 C C   . CYS B 2 176 ? 107.900 109.374 164.429 1.00 96.71  ? 166 CYS B C   1 
ATOM 3282 O O   . CYS B 2 176 ? 107.543 109.455 165.607 1.00 102.04 ? 166 CYS B O   1 
ATOM 3283 C CB  . CYS B 2 176 ? 110.380 109.576 164.156 1.00 96.64  ? 166 CYS B CB  1 
ATOM 3284 S SG  . CYS B 2 176 ? 111.599 109.833 162.856 1.00 108.03 ? 166 CYS B SG  1 
ATOM 3285 N N   . ALA B 2 177 ? 107.316 108.564 163.556 1.00 93.35  ? 167 ALA B N   1 
ATOM 3286 C CA  . ALA B 2 177 ? 106.126 107.807 163.904 1.00 91.58  ? 167 ALA B CA  1 
ATOM 3287 C C   . ALA B 2 177 ? 106.259 106.364 163.453 1.00 94.48  ? 167 ALA B C   1 
ATOM 3288 O O   . ALA B 2 177 ? 106.875 106.069 162.427 1.00 99.56  ? 167 ALA B O   1 
ATOM 3289 C CB  . ALA B 2 177 ? 104.872 108.427 163.280 1.00 90.95  ? 167 ALA B CB  1 
ATOM 3290 N N   . LEU B 2 178 ? 105.664 105.467 164.231 1.00 94.48  ? 168 LEU B N   1 
ATOM 3291 C CA  . LEU B 2 178 ? 105.576 104.053 163.899 1.00 91.49  ? 168 LEU B CA  1 
ATOM 3292 C C   . LEU B 2 178 ? 104.126 103.742 163.566 1.00 94.24  ? 168 LEU B C   1 
ATOM 3293 O O   . LEU B 2 178 ? 103.235 103.973 164.390 1.00 101.97 ? 168 LEU B O   1 
ATOM 3294 C CB  . LEU B 2 178 ? 106.066 103.185 165.055 1.00 91.43  ? 168 LEU B CB  1 
ATOM 3295 C CG  . LEU B 2 178 ? 106.228 101.699 164.755 1.00 92.15  ? 168 LEU B CG  1 
ATOM 3296 C CD1 . LEU B 2 178 ? 107.652 101.254 165.037 1.00 93.04  ? 168 LEU B CD1 1 
ATOM 3297 C CD2 . LEU B 2 178 ? 105.244 100.888 165.570 1.00 95.19  ? 168 LEU B CD2 1 
ATOM 3298 N N   . TRP B 2 179 ? 103.892 103.221 162.368 1.00 92.14  ? 169 TRP B N   1 
ATOM 3299 C CA  . TRP B 2 179 ? 102.548 103.028 161.846 1.00 95.99  ? 169 TRP B CA  1 
ATOM 3300 C C   . TRP B 2 179 ? 102.242 101.544 161.739 1.00 98.75  ? 169 TRP B C   1 
ATOM 3301 O O   . TRP B 2 179 ? 103.033 100.785 161.172 1.00 102.45 ? 169 TRP B O   1 
ATOM 3302 C CB  . TRP B 2 179 ? 102.395 103.674 160.468 1.00 95.88  ? 169 TRP B CB  1 
ATOM 3303 C CG  . TRP B 2 179 ? 102.210 105.153 160.475 1.00 91.06  ? 169 TRP B CG  1 
ATOM 3304 C CD1 . TRP B 2 179 ? 103.185 106.097 160.389 1.00 90.96  ? 169 TRP B CD1 1 
ATOM 3305 C CD2 . TRP B 2 179 ? 100.970 105.861 160.547 1.00 90.25  ? 169 TRP B CD2 1 
ATOM 3306 N NE1 . TRP B 2 179 ? 102.632 107.352 160.412 1.00 90.58  ? 169 TRP B NE1 1 
ATOM 3307 C CE2 . TRP B 2 179 ? 101.271 107.234 160.508 1.00 90.04  ? 169 TRP B CE2 1 
ATOM 3308 C CE3 . TRP B 2 179 ? 99.633  105.467 160.642 1.00 96.79  ? 169 TRP B CE3 1 
ATOM 3309 C CZ2 . TRP B 2 179 ? 100.288 108.216 160.560 1.00 97.32  ? 169 TRP B CZ2 1 
ATOM 3310 C CZ3 . TRP B 2 179 ? 98.657  106.443 160.698 1.00 100.38 ? 169 TRP B CZ3 1 
ATOM 3311 C CH2 . TRP B 2 179 ? 98.989  107.801 160.658 1.00 101.76 ? 169 TRP B CH2 1 
ATOM 3312 N N   . ASP B 2 180 ? 101.100 101.137 162.277 1.00 103.60 ? 170 ASP B N   1 
ATOM 3313 C CA  . ASP B 2 180 ? 100.564 99.818  161.990 1.00 108.79 ? 170 ASP B CA  1 
ATOM 3314 C C   . ASP B 2 180 ? 99.878  99.831  160.629 1.00 110.89 ? 170 ASP B C   1 
ATOM 3315 O O   . ASP B 2 180 ? 99.504  100.886 160.109 1.00 111.61 ? 170 ASP B O   1 
ATOM 3316 C CB  . ASP B 2 180 ? 99.579  99.384  163.074 1.00 107.67 ? 170 ASP B CB  1 
ATOM 3317 C CG  . ASP B 2 180 ? 99.494  97.880  163.216 1.00 108.29 ? 170 ASP B CG  1 
ATOM 3318 O OD1 . ASP B 2 180 ? 99.683  97.171  162.206 1.00 109.63 ? 170 ASP B OD1 1 
ATOM 3319 O OD2 . ASP B 2 180 ? 99.233  97.403  164.340 1.00 113.21 ? 170 ASP B OD2 1 
ATOM 3320 N N   . ILE B 2 181 ? 99.714  98.644  160.052 1.00 107.09 ? 171 ILE B N   1 
ATOM 3321 C CA  . ILE B 2 181 ? 99.179  98.530  158.701 1.00 105.28 ? 171 ILE B CA  1 
ATOM 3322 C C   . ILE B 2 181 ? 97.664  98.358  158.669 1.00 108.60 ? 171 ILE B C   1 
ATOM 3323 O O   . ILE B 2 181 ? 96.986  99.105  157.945 1.00 110.03 ? 171 ILE B O   1 
ATOM 3324 C CB  . ILE B 2 181 ? 99.869  97.372  157.948 1.00 106.82 ? 171 ILE B CB  1 
ATOM 3325 C CG1 . ILE B 2 181 ? 101.261 97.803  157.501 1.00 104.34 ? 171 ILE B CG1 1 
ATOM 3326 C CG2 . ILE B 2 181 ? 99.065  96.930  156.730 1.00 105.56 ? 171 ILE B CG2 1 
ATOM 3327 C CD1 . ILE B 2 181 ? 101.239 98.993  156.602 1.00 95.65  ? 171 ILE B CD1 1 
ATOM 3328 N N   . GLU B 2 182 ? 97.113  97.418  159.440 1.00 110.43 ? 172 GLU B N   1 
ATOM 3329 C CA  . GLU B 2 182 ? 95.698  97.074  159.327 1.00 110.54 ? 172 GLU B CA  1 
ATOM 3330 C C   . GLU B 2 182 ? 94.802  98.191  159.849 1.00 105.23 ? 172 GLU B C   1 
ATOM 3331 O O   . GLU B 2 182 ? 93.912  98.670  159.140 1.00 104.54 ? 172 GLU B O   1 
ATOM 3332 C CB  . GLU B 2 182 ? 95.419  95.768  160.074 1.00 113.98 ? 172 GLU B CB  1 
ATOM 3333 C CG  . GLU B 2 182 ? 95.491  94.528  159.201 1.00 117.15 ? 172 GLU B CG  1 
ATOM 3334 C CD  . GLU B 2 182 ? 96.878  94.293  158.637 1.00 123.62 ? 172 GLU B CD  1 
ATOM 3335 O OE1 . GLU B 2 182 ? 97.818  94.087  159.434 1.00 123.94 ? 172 GLU B OE1 1 
ATOM 3336 O OE2 . GLU B 2 182 ? 97.028  94.315  157.398 1.00 123.30 ? 172 GLU B OE2 1 
ATOM 3337 N N   . THR B 2 183 ? 95.024  98.621  161.090 1.00 105.03 ? 173 THR B N   1 
ATOM 3338 C CA  . THR B 2 183 ? 94.231  99.708  161.645 1.00 107.00 ? 173 THR B CA  1 
ATOM 3339 C C   . THR B 2 183 ? 94.601  101.060 161.057 1.00 107.94 ? 173 THR B C   1 
ATOM 3340 O O   . THR B 2 183 ? 93.767  101.972 161.067 1.00 110.82 ? 173 THR B O   1 
ATOM 3341 C CB  . THR B 2 183 ? 94.383  99.759  163.166 1.00 105.73 ? 173 THR B CB  1 
ATOM 3342 O OG1 . THR B 2 183 ? 95.607  100.423 163.502 1.00 102.35 ? 173 THR B OG1 1 
ATOM 3343 C CG2 . THR B 2 183 ? 94.396  98.353  163.748 1.00 106.66 ? 173 THR B CG2 1 
ATOM 3344 N N   . GLY B 2 184 ? 95.816  101.205 160.539 1.00 106.95 ? 174 GLY B N   1 
ATOM 3345 C CA  . GLY B 2 184 ? 96.263  102.474 159.993 1.00 108.96 ? 174 GLY B CA  1 
ATOM 3346 C C   . GLY B 2 184 ? 96.407  103.568 161.027 1.00 111.93 ? 174 GLY B C   1 
ATOM 3347 O O   . GLY B 2 184 ? 95.983  104.705 160.784 1.00 111.14 ? 174 GLY B O   1 
ATOM 3348 N N   . GLN B 2 185 ? 96.981  103.251 162.184 1.00 109.84 ? 175 GLN B N   1 
ATOM 3349 C CA  . GLN B 2 185 ? 97.107  104.196 163.280 1.00 108.47 ? 175 GLN B CA  1 
ATOM 3350 C C   . GLN B 2 185 ? 98.549  104.242 163.762 1.00 98.23  ? 175 GLN B C   1 
ATOM 3351 O O   . GLN B 2 185 ? 99.339  103.327 163.522 1.00 95.30  ? 175 GLN B O   1 
ATOM 3352 C CB  . GLN B 2 185 ? 96.180  103.835 164.452 1.00 111.72 ? 175 GLN B CB  1 
ATOM 3353 C CG  . GLN B 2 185 ? 94.728  103.604 164.065 1.00 111.27 ? 175 GLN B CG  1 
ATOM 3354 C CD  . GLN B 2 185 ? 94.000  104.891 163.729 1.00 115.74 ? 175 GLN B CD  1 
ATOM 3355 O OE1 . GLN B 2 185 ? 94.423  105.979 164.120 1.00 117.58 ? 175 GLN B OE1 1 
ATOM 3356 N NE2 . GLN B 2 185 ? 92.898  104.772 162.997 1.00 119.17 ? 175 GLN B NE2 1 
ATOM 3357 N N   . GLN B 2 186 ? 98.881  105.331 164.447 1.00 95.57  ? 176 GLN B N   1 
ATOM 3358 C CA  . GLN B 2 186 ? 100.204 105.510 165.031 1.00 93.24  ? 176 GLN B CA  1 
ATOM 3359 C C   . GLN B 2 186 ? 100.284 104.707 166.321 1.00 96.71  ? 176 GLN B C   1 
ATOM 3360 O O   . GLN B 2 186 ? 99.642  105.055 167.317 1.00 99.17  ? 176 GLN B O   1 
ATOM 3361 C CB  . GLN B 2 186 ? 100.471 106.987 165.302 1.00 96.10  ? 176 GLN B CB  1 
ATOM 3362 C CG  . GLN B 2 186 ? 100.672 107.824 164.065 1.00 100.44 ? 176 GLN B CG  1 
ATOM 3363 C CD  . GLN B 2 186 ? 101.488 109.068 164.336 1.00 108.71 ? 176 GLN B CD  1 
ATOM 3364 O OE1 . GLN B 2 186 ? 101.978 109.272 165.446 1.00 109.18 ? 176 GLN B OE1 1 
ATOM 3365 N NE2 . GLN B 2 186 ? 101.638 109.911 163.322 1.00 108.67 ? 176 GLN B NE2 1 
ATOM 3366 N N   . THR B 2 187 ? 101.063 103.626 166.307 1.00 96.18  ? 177 THR B N   1 
ATOM 3367 C CA  . THR B 2 187 ? 101.268 102.857 167.528 1.00 95.51  ? 177 THR B CA  1 
ATOM 3368 C C   . THR B 2 187 ? 102.124 103.632 168.523 1.00 96.63  ? 177 THR B C   1 
ATOM 3369 O O   . THR B 2 187 ? 101.766 103.760 169.699 1.00 98.78  ? 177 THR B O   1 
ATOM 3370 C CB  . THR B 2 187 ? 101.908 101.509 167.195 1.00 98.78  ? 177 THR B CB  1 
ATOM 3371 O OG1 . THR B 2 187 ? 100.995 100.726 166.416 1.00 101.99 ? 177 THR B OG1 1 
ATOM 3372 C CG2 . THR B 2 187 ? 102.257 100.748 168.465 1.00 99.19  ? 177 THR B CG2 1 
ATOM 3373 N N   . THR B 2 188 ? 103.249 104.176 168.064 1.00 97.63  ? 178 THR B N   1 
ATOM 3374 C CA  . THR B 2 188 ? 104.152 104.942 168.910 1.00 98.38  ? 178 THR B CA  1 
ATOM 3375 C C   . THR B 2 188 ? 104.720 106.105 168.112 1.00 96.49  ? 178 THR B C   1 
ATOM 3376 O O   . THR B 2 188 ? 105.035 105.957 166.929 1.00 96.90  ? 178 THR B O   1 
ATOM 3377 C CB  . THR B 2 188 ? 105.300 104.075 169.447 1.00 100.87 ? 178 THR B CB  1 
ATOM 3378 O OG1 . THR B 2 188 ? 104.814 102.764 169.758 1.00 106.29 ? 178 THR B OG1 1 
ATOM 3379 C CG2 . THR B 2 188 ? 105.894 104.693 170.704 1.00 96.47  ? 178 THR B CG2 1 
ATOM 3380 N N   . THR B 2 189 ? 104.851 107.256 168.762 1.00 96.11  ? 179 THR B N   1 
ATOM 3381 C CA  . THR B 2 189 ? 105.411 108.446 168.142 1.00 99.85  ? 179 THR B CA  1 
ATOM 3382 C C   . THR B 2 189 ? 106.685 108.855 168.869 1.00 101.70 ? 179 THR B C   1 
ATOM 3383 O O   . THR B 2 189 ? 106.821 108.660 170.080 1.00 107.30 ? 179 THR B O   1 
ATOM 3384 C CB  . THR B 2 189 ? 104.407 109.605 168.142 1.00 101.16 ? 179 THR B CB  1 
ATOM 3385 O OG1 . THR B 2 189 ? 105.081 110.824 167.811 1.00 103.59 ? 179 THR B OG1 1 
ATOM 3386 C CG2 . THR B 2 189 ? 103.745 109.747 169.503 1.00 99.35  ? 179 THR B CG2 1 
ATOM 3387 N N   . PHE B 2 190 ? 107.623 109.417 168.113 1.00 96.15  ? 180 PHE B N   1 
ATOM 3388 C CA  . PHE B 2 190 ? 108.951 109.765 168.610 1.00 96.01  ? 180 PHE B CA  1 
ATOM 3389 C C   . PHE B 2 190 ? 109.145 111.271 168.461 1.00 99.94  ? 180 PHE B C   1 
ATOM 3390 O O   . PHE B 2 190 ? 109.463 111.755 167.371 1.00 104.86 ? 180 PHE B O   1 
ATOM 3391 C CB  . PHE B 2 190 ? 110.024 108.990 167.855 1.00 99.31  ? 180 PHE B CB  1 
ATOM 3392 C CG  . PHE B 2 190 ? 109.755 107.518 167.758 1.00 102.13 ? 180 PHE B CG  1 
ATOM 3393 C CD1 . PHE B 2 190 ? 110.046 106.680 168.816 1.00 102.31 ? 180 PHE B CD1 1 
ATOM 3394 C CD2 . PHE B 2 190 ? 109.227 106.970 166.605 1.00 104.58 ? 180 PHE B CD2 1 
ATOM 3395 C CE1 . PHE B 2 190 ? 109.807 105.329 168.729 1.00 100.87 ? 180 PHE B CE1 1 
ATOM 3396 C CE2 . PHE B 2 190 ? 108.984 105.618 166.514 1.00 103.06 ? 180 PHE B CE2 1 
ATOM 3397 C CZ  . PHE B 2 190 ? 109.276 104.797 167.577 1.00 102.72 ? 180 PHE B CZ  1 
ATOM 3398 N N   . THR B 2 191 ? 108.957 112.011 169.551 1.00 97.63  ? 181 THR B N   1 
ATOM 3399 C CA  . THR B 2 191 ? 109.032 113.472 169.551 1.00 95.51  ? 181 THR B CA  1 
ATOM 3400 C C   . THR B 2 191 ? 110.180 113.906 170.457 1.00 91.19  ? 181 THR B C   1 
ATOM 3401 O O   . THR B 2 191 ? 109.996 114.086 171.662 1.00 94.83  ? 181 THR B O   1 
ATOM 3402 C CB  . THR B 2 191 ? 107.709 114.105 170.009 1.00 104.65 ? 181 THR B CB  1 
ATOM 3403 O OG1 . THR B 2 191 ? 107.646 114.099 171.441 1.00 107.06 ? 181 THR B OG1 1 
ATOM 3404 C CG2 . THR B 2 191 ? 106.514 113.348 169.450 1.00 104.32 ? 181 THR B CG2 1 
ATOM 3405 N N   . GLY B 2 192 ? 111.367 114.064 169.879 1.00 87.25  ? 182 GLY B N   1 
ATOM 3406 C CA  . GLY B 2 192 ? 112.490 114.585 170.632 1.00 84.07  ? 182 GLY B CA  1 
ATOM 3407 C C   . GLY B 2 192 ? 113.357 115.558 169.860 1.00 87.12  ? 182 GLY B C   1 
ATOM 3408 O O   . GLY B 2 192 ? 114.275 116.160 170.424 1.00 87.12  ? 182 GLY B O   1 
ATOM 3409 N N   . HIS B 2 193 ? 113.078 115.725 168.576 1.00 90.87  ? 183 HIS B N   1 
ATOM 3410 C CA  . HIS B 2 193 ? 113.887 116.576 167.721 1.00 90.11  ? 183 HIS B CA  1 
ATOM 3411 C C   . HIS B 2 193 ? 113.374 118.011 167.759 1.00 92.34  ? 183 HIS B C   1 
ATOM 3412 O O   . HIS B 2 193 ? 112.210 118.274 168.068 1.00 96.25  ? 183 HIS B O   1 
ATOM 3413 C CB  . HIS B 2 193 ? 113.872 116.060 166.284 1.00 90.46  ? 183 HIS B CB  1 
ATOM 3414 C CG  . HIS B 2 193 ? 114.838 114.948 166.029 1.00 93.10  ? 183 HIS B CG  1 
ATOM 3415 N ND1 . HIS B 2 193 ? 116.171 115.167 165.758 1.00 94.04  ? 183 HIS B ND1 1 
ATOM 3416 C CD2 . HIS B 2 193 ? 114.663 113.607 165.996 1.00 95.39  ? 183 HIS B CD2 1 
ATOM 3417 C CE1 . HIS B 2 193 ? 116.776 114.008 165.569 1.00 94.99  ? 183 HIS B CE1 1 
ATOM 3418 N NE2 . HIS B 2 193 ? 115.884 113.045 165.710 1.00 96.17  ? 183 HIS B NE2 1 
ATOM 3419 N N   . THR B 2 194 ? 114.265 118.947 167.437 1.00 89.76  ? 184 THR B N   1 
ATOM 3420 C CA  . THR B 2 194 ? 113.894 120.353 167.352 1.00 89.92  ? 184 THR B CA  1 
ATOM 3421 C C   . THR B 2 194 ? 113.789 120.852 165.921 1.00 85.85  ? 184 THR B C   1 
ATOM 3422 O O   . THR B 2 194 ? 113.005 121.766 165.652 1.00 87.76  ? 184 THR B O   1 
ATOM 3423 C CB  . THR B 2 194 ? 114.898 121.225 168.113 1.00 93.37  ? 184 THR B CB  1 
ATOM 3424 O OG1 . THR B 2 194 ? 116.016 121.520 167.271 1.00 93.91  ? 184 THR B OG1 1 
ATOM 3425 C CG2 . THR B 2 194 ? 115.387 120.512 169.362 1.00 91.55  ? 184 THR B CG2 1 
ATOM 3426 N N   . GLY B 2 195 ? 114.568 120.285 165.001 1.00 85.01  ? 185 GLY B N   1 
ATOM 3427 C CA  . GLY B 2 195 ? 114.427 120.549 163.589 1.00 88.85  ? 185 GLY B CA  1 
ATOM 3428 C C   . GLY B 2 195 ? 113.760 119.369 162.901 1.00 95.15  ? 185 GLY B C   1 
ATOM 3429 O O   . GLY B 2 195 ? 113.569 118.304 163.483 1.00 99.17  ? 185 GLY B O   1 
ATOM 3430 N N   . ASP B 2 196 ? 113.395 119.582 161.641 1.00 96.87  ? 186 ASP B N   1 
ATOM 3431 C CA  . ASP B 2 196 ? 112.690 118.545 160.902 1.00 96.19  ? 186 ASP B CA  1 
ATOM 3432 C C   . ASP B 2 196 ? 113.635 117.420 160.494 1.00 91.89  ? 186 ASP B C   1 
ATOM 3433 O O   . ASP B 2 196 ? 114.765 117.653 160.062 1.00 91.83  ? 186 ASP B O   1 
ATOM 3434 C CB  . ASP B 2 196 ? 111.976 119.139 159.685 1.00 97.83  ? 186 ASP B CB  1 
ATOM 3435 C CG  . ASP B 2 196 ? 112.890 119.963 158.810 1.00 103.41 ? 186 ASP B CG  1 
ATOM 3436 O OD1 . ASP B 2 196 ? 112.489 120.305 157.676 1.00 106.54 ? 186 ASP B OD1 1 
ATOM 3437 O OD2 . ASP B 2 196 ? 113.989 120.311 159.277 1.00 101.59 ? 186 ASP B OD2 1 
ATOM 3438 N N   . VAL B 2 197 ? 113.158 116.193 160.653 1.00 89.41  ? 187 VAL B N   1 
ATOM 3439 C CA  . VAL B 2 197 ? 113.927 114.978 160.408 1.00 86.07  ? 187 VAL B CA  1 
ATOM 3440 C C   . VAL B 2 197 ? 113.877 114.638 158.930 1.00 85.90  ? 187 VAL B C   1 
ATOM 3441 O O   . VAL B 2 197 ? 112.819 114.735 158.297 1.00 93.25  ? 187 VAL B O   1 
ATOM 3442 C CB  . VAL B 2 197 ? 113.370 113.818 161.253 1.00 84.67  ? 187 VAL B CB  1 
ATOM 3443 C CG1 . VAL B 2 197 ? 114.322 112.648 161.258 1.00 87.61  ? 187 VAL B CG1 1 
ATOM 3444 C CG2 . VAL B 2 197 ? 113.108 114.289 162.675 1.00 87.26  ? 187 VAL B CG2 1 
ATOM 3445 N N   . MET B 2 198 ? 115.012 114.233 158.362 1.00 82.32  ? 188 MET B N   1 
ATOM 3446 C CA  . MET B 2 198 ? 114.988 113.675 157.020 1.00 84.82  ? 188 MET B CA  1 
ATOM 3447 C C   . MET B 2 198 ? 115.211 112.170 156.995 1.00 86.87  ? 188 MET B C   1 
ATOM 3448 O O   . MET B 2 198 ? 114.299 111.427 156.621 1.00 92.83  ? 188 MET B O   1 
ATOM 3449 C CB  . MET B 2 198 ? 115.982 114.352 156.075 1.00 85.88  ? 188 MET B CB  1 
ATOM 3450 C CG  . MET B 2 198 ? 115.968 115.844 156.104 1.00 90.35  ? 188 MET B CG  1 
ATOM 3451 S SD  . MET B 2 198 ? 115.086 116.298 154.600 1.00 127.58 ? 188 MET B SD  1 
ATOM 3452 C CE  . MET B 2 198 ? 116.408 116.760 153.505 1.00 104.77 ? 188 MET B CE  1 
ATOM 3453 N N   . SER B 2 199 ? 116.369 111.687 157.410 1.00 82.82  ? 189 SER B N   1 
ATOM 3454 C CA  . SER B 2 199 ? 116.742 110.321 157.095 1.00 78.36  ? 189 SER B CA  1 
ATOM 3455 C C   . SER B 2 199 ? 116.789 109.484 158.360 1.00 78.41  ? 189 SER B C   1 
ATOM 3456 O O   . SER B 2 199 ? 117.350 109.901 159.377 1.00 88.21  ? 189 SER B O   1 
ATOM 3457 C CB  . SER B 2 199 ? 118.089 110.278 156.378 1.00 83.62  ? 189 SER B CB  1 
ATOM 3458 O OG  . SER B 2 199 ? 117.917 110.260 154.971 1.00 89.68  ? 189 SER B OG  1 
ATOM 3459 N N   . LEU B 2 200 ? 116.182 108.309 158.288 1.00 71.20  ? 190 LEU B N   1 
ATOM 3460 C CA  . LEU B 2 200 ? 116.230 107.342 159.366 1.00 75.99  ? 190 LEU B CA  1 
ATOM 3461 C C   . LEU B 2 200 ? 116.583 105.986 158.778 1.00 76.66  ? 190 LEU B C   1 
ATOM 3462 O O   . LEU B 2 200 ? 116.138 105.638 157.682 1.00 81.54  ? 190 LEU B O   1 
ATOM 3463 C CB  . LEU B 2 200 ? 114.907 107.311 160.138 1.00 80.69  ? 190 LEU B CB  1 
ATOM 3464 C CG  . LEU B 2 200 ? 113.742 106.374 159.832 1.00 84.31  ? 190 LEU B CG  1 
ATOM 3465 C CD1 . LEU B 2 200 ? 112.697 106.551 160.904 1.00 89.60  ? 190 LEU B CD1 1 
ATOM 3466 C CD2 . LEU B 2 200 ? 113.130 106.675 158.492 1.00 84.10  ? 190 LEU B CD2 1 
ATOM 3467 N N   . SER B 2 201 ? 117.421 105.246 159.491 1.00 77.61  ? 191 SER B N   1 
ATOM 3468 C CA  . SER B 2 201 ? 117.920 103.966 159.022 1.00 78.81  ? 191 SER B CA  1 
ATOM 3469 C C   . SER B 2 201 ? 117.681 102.918 160.092 1.00 80.65  ? 191 SER B C   1 
ATOM 3470 O O   . SER B 2 201 ? 117.907 103.167 161.278 1.00 85.87  ? 191 SER B O   1 
ATOM 3471 C CB  . SER B 2 201 ? 119.408 104.036 158.680 1.00 85.54  ? 191 SER B CB  1 
ATOM 3472 O OG  . SER B 2 201 ? 120.209 103.979 159.849 1.00 97.35  ? 191 SER B OG  1 
ATOM 3473 N N   . LEU B 2 202 ? 117.237 101.746 159.665 1.00 80.77  ? 192 LEU B N   1 
ATOM 3474 C CA  . LEU B 2 202 ? 116.872 100.678 160.578 1.00 87.68  ? 192 LEU B CA  1 
ATOM 3475 C C   . LEU B 2 202 ? 118.073 99.798  160.884 1.00 96.46  ? 192 LEU B C   1 
ATOM 3476 O O   . LEU B 2 202 ? 118.896 99.519  160.008 1.00 96.01  ? 192 LEU B O   1 
ATOM 3477 C CB  . LEU B 2 202 ? 115.753 99.828  159.981 1.00 91.73  ? 192 LEU B CB  1 
ATOM 3478 C CG  . LEU B 2 202 ? 114.340 100.032 160.513 1.00 93.25  ? 192 LEU B CG  1 
ATOM 3479 C CD1 . LEU B 2 202 ? 114.010 101.506 160.608 1.00 90.82  ? 192 LEU B CD1 1 
ATOM 3480 C CD2 . LEU B 2 202 ? 113.361 99.325  159.601 1.00 89.86  ? 192 LEU B CD2 1 
ATOM 3481 N N   . ALA B 2 203 ? 118.162 99.359  162.135 1.00 101.81 ? 193 ALA B N   1 
ATOM 3482 C CA  . ALA B 2 203 ? 119.205 98.441  162.543 1.00 106.52 ? 193 ALA B CA  1 
ATOM 3483 C C   . ALA B 2 203 ? 118.946 97.059  161.943 1.00 107.53 ? 193 ALA B C   1 
ATOM 3484 O O   . ALA B 2 203 ? 117.807 96.730  161.604 1.00 106.92 ? 193 ALA B O   1 
ATOM 3485 C CB  . ALA B 2 203 ? 119.271 98.372  164.068 1.00 106.39 ? 193 ALA B CB  1 
ATOM 3486 N N   . PRO B 2 204 ? 119.996 96.247  161.765 1.00 108.49 ? 194 PRO B N   1 
ATOM 3487 C CA  . PRO B 2 204 ? 119.794 94.905  161.187 1.00 108.74 ? 194 PRO B CA  1 
ATOM 3488 C C   . PRO B 2 204 ? 118.921 93.974  162.013 1.00 111.01 ? 194 PRO B C   1 
ATOM 3489 O O   . PRO B 2 204 ? 118.324 93.050  161.446 1.00 112.09 ? 194 PRO B O   1 
ATOM 3490 C CB  . PRO B 2 204 ? 121.226 94.359  161.061 1.00 108.52 ? 194 PRO B CB  1 
ATOM 3491 C CG  . PRO B 2 204 ? 122.080 95.269  161.888 1.00 107.44 ? 194 PRO B CG  1 
ATOM 3492 C CD  . PRO B 2 204 ? 121.423 96.600  161.808 1.00 105.03 ? 194 PRO B CD  1 
ATOM 3493 N N   . ASP B 2 205 ? 118.818 94.173  163.324 1.00 113.40 ? 195 ASP B N   1 
ATOM 3494 C CA  . ASP B 2 205 ? 117.987 93.304  164.149 1.00 116.09 ? 195 ASP B CA  1 
ATOM 3495 C C   . ASP B 2 205 ? 116.546 93.783  164.250 1.00 115.53 ? 195 ASP B C   1 
ATOM 3496 O O   . ASP B 2 205 ? 115.759 93.163  164.973 1.00 112.14 ? 195 ASP B O   1 
ATOM 3497 C CB  . ASP B 2 205 ? 118.585 93.156  165.554 1.00 120.11 ? 195 ASP B CB  1 
ATOM 3498 C CG  . ASP B 2 205 ? 118.986 94.479  166.162 1.00 123.75 ? 195 ASP B CG  1 
ATOM 3499 O OD1 . ASP B 2 205 ? 119.301 95.409  165.397 1.00 119.47 ? 195 ASP B OD1 1 
ATOM 3500 O OD2 . ASP B 2 205 ? 118.986 94.590  167.406 1.00 125.95 ? 195 ASP B OD2 1 
ATOM 3501 N N   . THR B 2 206 ? 116.184 94.836  163.507 1.00 116.88 ? 196 THR B N   1 
ATOM 3502 C CA  . THR B 2 206 ? 114.844 95.447  163.468 1.00 114.84 ? 196 THR B CA  1 
ATOM 3503 C C   . THR B 2 206 ? 114.311 95.749  164.868 1.00 106.76 ? 196 THR B C   1 
ATOM 3504 O O   . THR B 2 206 ? 113.168 95.438  165.210 1.00 106.21 ? 196 THR B O   1 
ATOM 3505 C CB  . THR B 2 206 ? 113.833 94.607  162.667 1.00 117.24 ? 196 THR B CB  1 
ATOM 3506 O OG1 . THR B 2 206 ? 113.999 93.203  162.905 1.00 122.91 ? 196 THR B OG1 1 
ATOM 3507 C CG2 . THR B 2 206 ? 113.979 94.882  161.175 1.00 111.52 ? 196 THR B CG2 1 
ATOM 3508 N N   . ARG B 2 207 ? 115.159 96.367  165.687 1.00 104.48 ? 197 ARG B N   1 
ATOM 3509 C CA  . ARG B 2 207 ? 114.757 96.774  167.029 1.00 103.75 ? 197 ARG B CA  1 
ATOM 3510 C C   . ARG B 2 207 ? 115.066 98.224  167.361 1.00 108.30 ? 197 ARG B C   1 
ATOM 3511 O O   . ARG B 2 207 ? 114.369 98.798  168.204 1.00 113.33 ? 197 ARG B O   1 
ATOM 3512 C CB  . ARG B 2 207 ? 115.416 95.875  168.080 1.00 104.57 ? 197 ARG B CB  1 
ATOM 3513 C CG  . ARG B 2 207 ? 114.524 95.559  169.266 1.00 104.70 ? 197 ARG B CG  1 
ATOM 3514 C CD  . ARG B 2 207 ? 114.887 94.216  169.888 1.00 107.35 ? 197 ARG B CD  1 
ATOM 3515 N NE  . ARG B 2 207 ? 114.998 93.152  168.896 1.00 115.45 ? 197 ARG B NE  1 
ATOM 3516 C CZ  . ARG B 2 207 ? 113.972 92.561  168.298 1.00 114.62 ? 197 ARG B CZ  1 
ATOM 3517 N NH1 . ARG B 2 207 ? 112.720 92.872  168.596 1.00 115.19 ? 197 ARG B NH1 1 
ATOM 3518 N NH2 . ARG B 2 207 ? 114.207 91.622  167.385 1.00 108.26 ? 197 ARG B NH2 1 
ATOM 3519 N N   . LEU B 2 208 ? 116.074 98.842  166.750 1.00 103.90 ? 198 LEU B N   1 
ATOM 3520 C CA  . LEU B 2 208 ? 116.391 100.243 166.972 1.00 96.42  ? 198 LEU B CA  1 
ATOM 3521 C C   . LEU B 2 208 ? 116.549 100.942 165.630 1.00 97.48  ? 198 LEU B C   1 
ATOM 3522 O O   . LEU B 2 208 ? 116.660 100.304 164.583 1.00 100.65 ? 198 LEU B O   1 
ATOM 3523 C CB  . LEU B 2 208 ? 117.671 100.422 167.798 1.00 93.38  ? 198 LEU B CB  1 
ATOM 3524 C CG  . LEU B 2 208 ? 117.991 99.418  168.905 1.00 91.44  ? 198 LEU B CG  1 
ATOM 3525 C CD1 . LEU B 2 208 ? 119.425 99.584  169.364 1.00 90.36  ? 198 LEU B CD1 1 
ATOM 3526 C CD2 . LEU B 2 208 ? 117.036 99.583  170.071 1.00 92.46  ? 198 LEU B CD2 1 
ATOM 3527 N N   . PHE B 2 209 ? 116.543 102.270 165.677 1.00 95.22  ? 199 PHE B N   1 
ATOM 3528 C CA  . PHE B 2 209 ? 116.811 103.091 164.505 1.00 94.67  ? 199 PHE B CA  1 
ATOM 3529 C C   . PHE B 2 209 ? 117.311 104.443 164.981 1.00 97.09  ? 199 PHE B C   1 
ATOM 3530 O O   . PHE B 2 209 ? 116.999 104.879 166.092 1.00 104.15 ? 199 PHE B O   1 
ATOM 3531 C CB  . PHE B 2 209 ? 115.572 103.250 163.613 1.00 91.04  ? 199 PHE B CB  1 
ATOM 3532 C CG  . PHE B 2 209 ? 114.431 103.994 164.257 1.00 91.33  ? 199 PHE B CG  1 
ATOM 3533 C CD1 . PHE B 2 209 ? 113.614 103.382 165.193 1.00 98.84  ? 199 PHE B CD1 1 
ATOM 3534 C CD2 . PHE B 2 209 ? 114.168 105.304 163.908 1.00 90.82  ? 199 PHE B CD2 1 
ATOM 3535 C CE1 . PHE B 2 209 ? 112.567 104.068 165.772 1.00 104.15 ? 199 PHE B CE1 1 
ATOM 3536 C CE2 . PHE B 2 209 ? 113.126 105.993 164.482 1.00 97.30  ? 199 PHE B CE2 1 
ATOM 3537 C CZ  . PHE B 2 209 ? 112.324 105.376 165.414 1.00 103.42 ? 199 PHE B CZ  1 
ATOM 3538 N N   . VAL B 2 210 ? 118.090 105.110 164.133 1.00 90.78  ? 200 VAL B N   1 
ATOM 3539 C CA  . VAL B 2 210 ? 118.604 106.433 164.454 1.00 91.11  ? 200 VAL B CA  1 
ATOM 3540 C C   . VAL B 2 210 ? 118.095 107.401 163.396 1.00 84.61  ? 200 VAL B C   1 
ATOM 3541 O O   . VAL B 2 210 ? 118.142 107.103 162.198 1.00 84.32  ? 200 VAL B O   1 
ATOM 3542 C CB  . VAL B 2 210 ? 120.145 106.459 164.546 1.00 96.72  ? 200 VAL B CB  1 
ATOM 3543 C CG1 . VAL B 2 210 ? 120.801 105.752 163.368 1.00 92.82  ? 200 VAL B CG1 1 
ATOM 3544 C CG2 . VAL B 2 210 ? 120.676 107.874 164.755 1.00 98.43  ? 200 VAL B CG2 1 
ATOM 3545 N N   . SER B 2 211 ? 117.567 108.536 163.840 1.00 88.06  ? 201 SER B N   1 
ATOM 3546 C CA  . SER B 2 211 ? 117.008 109.546 162.957 1.00 90.60  ? 201 SER B CA  1 
ATOM 3547 C C   . SER B 2 211 ? 117.816 110.829 163.070 1.00 95.79  ? 201 SER B C   1 
ATOM 3548 O O   . SER B 2 211 ? 118.130 111.280 164.176 1.00 100.44 ? 201 SER B O   1 
ATOM 3549 C CB  . SER B 2 211 ? 115.540 109.816 163.298 1.00 94.74  ? 201 SER B CB  1 
ATOM 3550 O OG  . SER B 2 211 ? 115.420 110.857 164.252 1.00 100.74 ? 201 SER B OG  1 
ATOM 3551 N N   . GLY B 2 212 ? 118.149 111.414 161.930 1.00 90.81  ? 202 GLY B N   1 
ATOM 3552 C CA  . GLY B 2 212 ? 118.931 112.641 161.883 1.00 92.60  ? 202 GLY B CA  1 
ATOM 3553 C C   . GLY B 2 212 ? 118.114 113.785 161.320 1.00 96.21  ? 202 GLY B C   1 
ATOM 3554 O O   . GLY B 2 212 ? 117.365 113.606 160.359 1.00 97.82  ? 202 GLY B O   1 
ATOM 3555 N N   . ALA B 2 213 ? 118.273 114.967 161.916 1.00 97.44  ? 203 ALA B N   1 
ATOM 3556 C CA  . ALA B 2 213 ? 117.467 116.119 161.536 1.00 97.64  ? 203 ALA B CA  1 
ATOM 3557 C C   . ALA B 2 213 ? 118.326 117.326 161.187 1.00 100.15 ? 203 ALA B C   1 
ATOM 3558 O O   . ALA B 2 213 ? 119.553 117.220 161.096 1.00 99.88  ? 203 ALA B O   1 
ATOM 3559 C CB  . ALA B 2 213 ? 116.499 116.482 162.662 1.00 93.51  ? 203 ALA B CB  1 
ATOM 3560 N N   . CYS B 2 214 ? 117.685 118.477 160.989 1.00 99.08  ? 204 CYS B N   1 
ATOM 3561 C CA  . CYS B 2 214 ? 118.370 119.737 160.742 1.00 99.08  ? 204 CYS B CA  1 
ATOM 3562 C C   . CYS B 2 214 ? 118.684 120.498 162.021 1.00 102.04 ? 204 CYS B C   1 
ATOM 3563 O O   . CYS B 2 214 ? 118.835 121.724 161.986 1.00 105.75 ? 204 CYS B O   1 
ATOM 3564 C CB  . CYS B 2 214 ? 117.551 120.606 159.788 1.00 101.50 ? 204 CYS B CB  1 
ATOM 3565 S SG  . CYS B 2 214 ? 116.928 119.701 158.359 1.00 110.78 ? 204 CYS B SG  1 
ATOM 3566 N N   . ASP B 2 215 ? 118.780 119.797 163.144 1.00 101.88 ? 205 ASP B N   1 
ATOM 3567 C CA  . ASP B 2 215 ? 119.294 120.347 164.386 1.00 96.76  ? 205 ASP B CA  1 
ATOM 3568 C C   . ASP B 2 215 ? 120.731 119.925 164.665 1.00 98.70  ? 205 ASP B C   1 
ATOM 3569 O O   . ASP B 2 215 ? 121.185 120.035 165.810 1.00 104.68 ? 205 ASP B O   1 
ATOM 3570 C CB  . ASP B 2 215 ? 118.317 120.022 165.534 1.00 97.04  ? 205 ASP B CB  1 
ATOM 3571 C CG  . ASP B 2 215 ? 118.292 118.538 165.964 1.00 102.51 ? 205 ASP B CG  1 
ATOM 3572 O OD1 . ASP B 2 215 ? 117.174 118.072 166.268 1.00 105.09 ? 205 ASP B OD1 1 
ATOM 3573 O OD2 . ASP B 2 215 ? 119.308 117.826 166.040 1.00 105.33 ? 205 ASP B OD2 1 
ATOM 3574 N N   . ALA B 2 216 ? 121.438 119.442 163.636 1.00 94.93  ? 206 ALA B N   1 
ATOM 3575 C CA  . ALA B 2 216 ? 122.847 119.040 163.699 1.00 96.32  ? 206 ALA B CA  1 
ATOM 3576 C C   . ALA B 2 216 ? 123.087 117.956 164.746 1.00 101.08 ? 206 ALA B C   1 
ATOM 3577 O O   . ALA B 2 216 ? 124.125 117.928 165.410 1.00 105.00 ? 206 ALA B O   1 
ATOM 3578 C CB  . ALA B 2 216 ? 123.763 120.244 163.939 1.00 97.02  ? 206 ALA B CB  1 
ATOM 3579 N N   . SER B 2 217 ? 122.124 117.050 164.891 1.00 100.29 ? 207 SER B N   1 
ATOM 3580 C CA  . SER B 2 217 ? 122.267 115.944 165.825 1.00 101.73 ? 207 SER B CA  1 
ATOM 3581 C C   . SER B 2 217 ? 121.430 114.767 165.351 1.00 100.46 ? 207 SER B C   1 
ATOM 3582 O O   . SER B 2 217 ? 120.500 114.918 164.557 1.00 102.41 ? 207 SER B O   1 
ATOM 3583 C CB  . SER B 2 217 ? 121.864 116.350 167.248 1.00 105.33 ? 207 SER B CB  1 
ATOM 3584 O OG  . SER B 2 217 ? 120.485 116.113 167.470 1.00 105.77 ? 207 SER B OG  1 
ATOM 3585 N N   . ALA B 2 218 ? 121.781 113.586 165.851 1.00 97.07  ? 208 ALA B N   1 
ATOM 3586 C CA  . ALA B 2 218 ? 121.073 112.354 165.546 1.00 94.35  ? 208 ALA B CA  1 
ATOM 3587 C C   . ALA B 2 218 ? 120.716 111.652 166.845 1.00 97.92  ? 208 ALA B C   1 
ATOM 3588 O O   . ALA B 2 218 ? 121.514 111.634 167.787 1.00 103.25 ? 208 ALA B O   1 
ATOM 3589 C CB  . ALA B 2 218 ? 121.913 111.433 164.661 1.00 92.20  ? 208 ALA B CB  1 
ATOM 3590 N N   . LYS B 2 219 ? 119.517 111.081 166.898 1.00 93.25  ? 209 LYS B N   1 
ATOM 3591 C CA  . LYS B 2 219 ? 119.004 110.451 168.105 1.00 95.11  ? 209 LYS B CA  1 
ATOM 3592 C C   . LYS B 2 219 ? 118.740 108.976 167.848 1.00 97.45  ? 209 LYS B C   1 
ATOM 3593 O O   . LYS B 2 219 ? 118.077 108.622 166.869 1.00 101.11 ? 209 LYS B O   1 
ATOM 3594 C CB  . LYS B 2 219 ? 117.719 111.131 168.581 1.00 91.48  ? 209 LYS B CB  1 
ATOM 3595 C CG  . LYS B 2 219 ? 117.815 112.634 168.693 1.00 93.69  ? 209 LYS B CG  1 
ATOM 3596 C CD  . LYS B 2 219 ? 116.755 113.184 169.623 1.00 95.58  ? 209 LYS B CD  1 
ATOM 3597 C CE  . LYS B 2 219 ? 117.354 113.571 170.961 1.00 97.77  ? 209 LYS B CE  1 
ATOM 3598 N NZ  . LYS B 2 219 ? 118.299 114.712 170.830 1.00 93.20  ? 209 LYS B NZ  1 
ATOM 3599 N N   . LEU B 2 220 ? 119.246 108.125 168.734 1.00 94.39  ? 210 LEU B N   1 
ATOM 3600 C CA  . LEU B 2 220 ? 118.922 106.709 168.698 1.00 88.74  ? 210 LEU B CA  1 
ATOM 3601 C C   . LEU B 2 220 ? 117.626 106.452 169.451 1.00 96.07  ? 210 LEU B C   1 
ATOM 3602 O O   . LEU B 2 220 ? 117.379 107.034 170.510 1.00 103.49 ? 210 LEU B O   1 
ATOM 3603 C CB  . LEU B 2 220 ? 120.048 105.883 169.311 1.00 91.02  ? 210 LEU B CB  1 
ATOM 3604 C CG  . LEU B 2 220 ? 120.012 104.388 169.009 1.00 96.05  ? 210 LEU B CG  1 
ATOM 3605 C CD1 . LEU B 2 220 ? 120.129 104.137 167.519 1.00 93.27  ? 210 LEU B CD1 1 
ATOM 3606 C CD2 . LEU B 2 220 ? 121.110 103.666 169.770 1.00 103.10 ? 210 LEU B CD2 1 
ATOM 3607 N N   . TRP B 2 221 ? 116.799 105.575 168.900 1.00 94.33  ? 211 TRP B N   1 
ATOM 3608 C CA  . TRP B 2 221 ? 115.499 105.245 169.461 1.00 93.32  ? 211 TRP B CA  1 
ATOM 3609 C C   . TRP B 2 221 ? 115.402 103.749 169.728 1.00 100.49 ? 211 TRP B C   1 
ATOM 3610 O O   . TRP B 2 221 ? 116.331 102.981 169.471 1.00 104.79 ? 211 TRP B O   1 
ATOM 3611 C CB  . TRP B 2 221 ? 114.374 105.668 168.517 1.00 88.17  ? 211 TRP B CB  1 
ATOM 3612 C CG  . TRP B 2 221 ? 114.386 107.095 168.109 1.00 88.02  ? 211 TRP B CG  1 
ATOM 3613 C CD1 . TRP B 2 221 ? 114.974 107.623 167.004 1.00 90.72  ? 211 TRP B CD1 1 
ATOM 3614 C CD2 . TRP B 2 221 ? 113.740 108.180 168.778 1.00 92.07  ? 211 TRP B CD2 1 
ATOM 3615 N NE1 . TRP B 2 221 ? 114.753 108.976 166.951 1.00 93.41  ? 211 TRP B NE1 1 
ATOM 3616 C CE2 . TRP B 2 221 ? 113.994 109.342 168.031 1.00 93.71  ? 211 TRP B CE2 1 
ATOM 3617 C CE3 . TRP B 2 221 ? 112.978 108.283 169.944 1.00 96.68  ? 211 TRP B CE3 1 
ATOM 3618 C CZ2 . TRP B 2 221 ? 113.516 110.590 168.409 1.00 94.33  ? 211 TRP B CZ2 1 
ATOM 3619 C CZ3 . TRP B 2 221 ? 112.504 109.519 170.317 1.00 95.18  ? 211 TRP B CZ3 1 
ATOM 3620 C CH2 . TRP B 2 221 ? 112.772 110.657 169.552 1.00 94.45  ? 211 TRP B CH2 1 
ATOM 3621 N N   . ASP B 2 222 ? 114.251 103.344 170.255 1.00 105.35 ? 212 ASP B N   1 
ATOM 3622 C CA  . ASP B 2 222 ? 113.797 101.964 170.206 1.00 107.59 ? 212 ASP B CA  1 
ATOM 3623 C C   . ASP B 2 222 ? 112.381 101.929 169.648 1.00 107.08 ? 212 ASP B C   1 
ATOM 3624 O O   . ASP B 2 222 ? 111.664 102.932 169.696 1.00 109.42 ? 212 ASP B O   1 
ATOM 3625 C CB  . ASP B 2 222 ? 113.909 101.256 171.590 1.00 109.98 ? 212 ASP B CB  1 
ATOM 3626 C CG  . ASP B 2 222 ? 113.028 101.871 172.700 1.00 118.35 ? 212 ASP B CG  1 
ATOM 3627 O OD1 . ASP B 2 222 ? 112.011 102.556 172.470 1.00 121.60 ? 212 ASP B OD1 1 
ATOM 3628 O OD2 . ASP B 2 222 ? 113.364 101.620 173.873 1.00 120.71 ? 212 ASP B OD2 1 
ATOM 3629 N N   . VAL B 2 223 ? 111.991 100.786 169.085 1.00 101.41 ? 213 VAL B N   1 
ATOM 3630 C CA  . VAL B 2 223 ? 110.626 100.651 168.585 1.00 101.84 ? 213 VAL B CA  1 
ATOM 3631 C C   . VAL B 2 223 ? 109.692 100.050 169.618 1.00 104.73 ? 213 VAL B C   1 
ATOM 3632 O O   . VAL B 2 223 ? 108.486 99.950  169.365 1.00 105.72 ? 213 VAL B O   1 
ATOM 3633 C CB  . VAL B 2 223 ? 110.598 99.804  167.300 1.00 102.37 ? 213 VAL B CB  1 
ATOM 3634 C CG1 . VAL B 2 223 ? 111.411 100.481 166.211 1.00 102.88 ? 213 VAL B CG1 1 
ATOM 3635 C CG2 . VAL B 2 223 ? 111.122 98.408  167.576 1.00 108.04 ? 213 VAL B CG2 1 
ATOM 3636 N N   . ARG B 2 224 ? 110.214 99.648  170.774 1.00 106.82 ? 214 ARG B N   1 
ATOM 3637 C CA  . ARG B 2 224 ? 109.409 99.024  171.815 1.00 111.19 ? 214 ARG B CA  1 
ATOM 3638 C C   . ARG B 2 224 ? 108.916 100.038 172.841 1.00 111.04 ? 214 ARG B C   1 
ATOM 3639 O O   . ARG B 2 224 ? 107.706 100.183 173.042 1.00 112.66 ? 214 ARG B O   1 
ATOM 3640 C CB  . ARG B 2 224 ? 110.218 97.924  172.508 1.00 115.03 ? 214 ARG B CB  1 
ATOM 3641 C CG  . ARG B 2 224 ? 110.156 96.548  171.847 1.00 117.12 ? 214 ARG B CG  1 
ATOM 3642 C CD  . ARG B 2 224 ? 108.817 96.266  171.181 1.00 124.85 ? 214 ARG B CD  1 
ATOM 3643 N NE  . ARG B 2 224 ? 108.853 95.038  170.395 1.00 129.49 ? 214 ARG B NE  1 
ATOM 3644 C CZ  . ARG B 2 224 ? 108.809 94.993  169.070 1.00 127.22 ? 214 ARG B CZ  1 
ATOM 3645 N NH1 . ARG B 2 224 ? 108.717 96.094  168.343 1.00 123.85 ? 214 ARG B NH1 1 
ATOM 3646 N NH2 . ARG B 2 224 ? 108.856 93.812  168.460 1.00 125.30 ? 214 ARG B NH2 1 
ATOM 3647 N N   . GLU B 2 225 ? 109.835 100.748 173.494 1.00 110.56 ? 215 GLU B N   1 
ATOM 3648 C CA  . GLU B 2 225 ? 109.460 101.692 174.538 1.00 117.03 ? 215 GLU B CA  1 
ATOM 3649 C C   . GLU B 2 225 ? 109.163 103.084 174.002 1.00 116.35 ? 215 GLU B C   1 
ATOM 3650 O O   . GLU B 2 225 ? 108.340 103.798 174.585 1.00 117.39 ? 215 GLU B O   1 
ATOM 3651 C CB  . GLU B 2 225 ? 110.564 101.777 175.594 1.00 121.12 ? 215 GLU B CB  1 
ATOM 3652 C CG  . GLU B 2 225 ? 110.828 100.466 176.315 1.00 126.33 ? 215 GLU B CG  1 
ATOM 3653 C CD  . GLU B 2 225 ? 109.620 99.969  177.085 1.00 132.47 ? 215 GLU B CD  1 
ATOM 3654 O OE1 . GLU B 2 225 ? 108.979 100.785 177.780 1.00 128.93 ? 215 GLU B OE1 1 
ATOM 3655 O OE2 . GLU B 2 225 ? 109.311 98.762  176.993 1.00 137.11 ? 215 GLU B OE2 1 
ATOM 3656 N N   . GLY B 2 226 ? 109.813 103.491 172.915 1.00 116.06 ? 216 GLY B N   1 
ATOM 3657 C CA  . GLY B 2 226 ? 109.481 104.751 172.281 1.00 113.27 ? 216 GLY B CA  1 
ATOM 3658 C C   . GLY B 2 226 ? 110.186 105.970 172.826 1.00 113.01 ? 216 GLY B C   1 
ATOM 3659 O O   . GLY B 2 226 ? 109.720 107.090 172.596 1.00 107.90 ? 216 GLY B O   1 
ATOM 3660 N N   . MET B 2 227 ? 111.292 105.796 173.541 1.00 117.71 ? 217 MET B N   1 
ATOM 3661 C CA  . MET B 2 227 ? 112.066 106.910 174.065 1.00 115.47 ? 217 MET B CA  1 
ATOM 3662 C C   . MET B 2 227 ? 113.432 106.957 173.396 1.00 108.36 ? 217 MET B C   1 
ATOM 3663 O O   . MET B 2 227 ? 113.851 106.019 172.714 1.00 107.17 ? 217 MET B O   1 
ATOM 3664 C CB  . MET B 2 227 ? 112.230 106.810 175.588 1.00 121.98 ? 217 MET B CB  1 
ATOM 3665 C CG  . MET B 2 227 ? 111.151 106.007 176.293 1.00 129.90 ? 217 MET B CG  1 
ATOM 3666 S SD  . MET B 2 227 ? 111.472 105.834 178.061 1.00 166.34 ? 217 MET B SD  1 
ATOM 3667 C CE  . MET B 2 227 ? 110.716 104.246 178.402 1.00 135.91 ? 217 MET B CE  1 
ATOM 3668 N N   . CYS B 2 228 ? 114.125 108.072 173.598 1.00 106.64 ? 218 CYS B N   1 
ATOM 3669 C CA  . CYS B 2 228 ? 115.486 108.210 173.105 1.00 101.78 ? 218 CYS B CA  1 
ATOM 3670 C C   . CYS B 2 228 ? 116.439 107.345 173.915 1.00 103.46 ? 218 CYS B C   1 
ATOM 3671 O O   . CYS B 2 228 ? 116.147 106.944 175.045 1.00 108.88 ? 218 CYS B O   1 
ATOM 3672 C CB  . CYS B 2 228 ? 115.955 109.657 173.195 1.00 104.39 ? 218 CYS B CB  1 
ATOM 3673 S SG  . CYS B 2 228 ? 115.218 110.822 172.052 1.00 115.04 ? 218 CYS B SG  1 
ATOM 3674 N N   . ARG B 2 229 ? 117.593 107.058 173.324 1.00 100.56 ? 219 ARG B N   1 
ATOM 3675 C CA  . ARG B 2 229 ? 118.710 106.491 174.063 1.00 100.50 ? 219 ARG B CA  1 
ATOM 3676 C C   . ARG B 2 229 ? 119.922 107.406 174.076 1.00 101.77 ? 219 ARG B C   1 
ATOM 3677 O O   . ARG B 2 229 ? 120.406 107.766 175.155 1.00 107.20 ? 219 ARG B O   1 
ATOM 3678 C CB  . ARG B 2 229 ? 119.082 105.120 173.483 1.00 101.77 ? 219 ARG B CB  1 
ATOM 3679 C CG  . ARG B 2 229 ? 118.008 104.076 173.680 1.00 104.87 ? 219 ARG B CG  1 
ATOM 3680 C CD  . ARG B 2 229 ? 118.069 103.541 175.108 1.00 112.96 ? 219 ARG B CD  1 
ATOM 3681 N NE  . ARG B 2 229 ? 116.757 103.314 175.705 1.00 117.14 ? 219 ARG B NE  1 
ATOM 3682 C CZ  . ARG B 2 229 ? 115.916 102.348 175.359 1.00 116.65 ? 219 ARG B CZ  1 
ATOM 3683 N NH1 . ARG B 2 229 ? 116.231 101.441 174.447 1.00 115.37 ? 219 ARG B NH1 1 
ATOM 3684 N NH2 . ARG B 2 229 ? 114.728 102.282 175.954 1.00 112.83 ? 219 ARG B NH2 1 
ATOM 3685 N N   . GLN B 2 230 ? 120.412 107.814 172.911 1.00 97.47  ? 220 GLN B N   1 
ATOM 3686 C CA  . GLN B 2 230 ? 121.568 108.687 172.807 1.00 93.24  ? 220 GLN B CA  1 
ATOM 3687 C C   . GLN B 2 230 ? 121.178 109.976 172.092 1.00 92.05  ? 220 GLN B C   1 
ATOM 3688 O O   . GLN B 2 230 ? 120.118 110.071 171.469 1.00 95.44  ? 220 GLN B O   1 
ATOM 3689 C CB  . GLN B 2 230 ? 122.724 108.015 172.058 1.00 97.51  ? 220 GLN B CB  1 
ATOM 3690 C CG  . GLN B 2 230 ? 123.330 106.676 172.547 1.00 104.71 ? 220 GLN B CG  1 
ATOM 3691 C CD  . GLN B 2 230 ? 122.972 106.230 173.953 1.00 118.72 ? 220 GLN B CD  1 
ATOM 3692 O OE1 . GLN B 2 230 ? 123.164 106.958 174.929 1.00 120.04 ? 220 GLN B OE1 1 
ATOM 3693 N NE2 . GLN B 2 230 ? 122.442 105.020 174.061 1.00 122.34 ? 220 GLN B NE2 1 
ATOM 3694 N N   . THR B 2 231 ? 122.050 110.976 172.196 1.00 91.94  ? 221 THR B N   1 
ATOM 3695 C CA  . THR B 2 231 ? 121.786 112.324 171.694 1.00 96.17  ? 221 THR B CA  1 
ATOM 3696 C C   . THR B 2 231 ? 123.016 112.907 170.990 1.00 100.05 ? 221 THR B C   1 
ATOM 3697 O O   . THR B 2 231 ? 123.464 114.013 171.295 1.00 110.09 ? 221 THR B O   1 
ATOM 3698 C CB  . THR B 2 231 ? 121.285 113.222 172.831 1.00 108.14 ? 221 THR B CB  1 
ATOM 3699 O OG1 . THR B 2 231 ? 121.072 114.556 172.348 1.00 112.78 ? 221 THR B OG1 1 
ATOM 3700 C CG2 . THR B 2 231 ? 122.221 113.208 174.060 1.00 105.78 ? 221 THR B CG2 1 
ATOM 3701 N N   . PHE B 2 232 ? 123.569 112.159 170.026 1.00 96.68  ? 222 PHE B N   1 
ATOM 3702 C CA  . PHE B 2 232 ? 124.855 112.470 169.393 1.00 103.29 ? 222 PHE B CA  1 
ATOM 3703 C C   . PHE B 2 232 ? 124.909 113.862 168.771 1.00 107.48 ? 222 PHE B C   1 
ATOM 3704 O O   . PHE B 2 232 ? 124.209 114.135 167.792 1.00 111.28 ? 222 PHE B O   1 
ATOM 3705 C CB  . PHE B 2 232 ? 125.238 111.502 168.260 1.00 102.13 ? 222 PHE B CB  1 
ATOM 3706 C CG  . PHE B 2 232 ? 125.039 110.042 168.551 1.00 96.34  ? 222 PHE B CG  1 
ATOM 3707 C CD1 . PHE B 2 232 ? 123.781 109.463 168.527 1.00 100.12 ? 222 PHE B CD1 1 
ATOM 3708 C CD2 . PHE B 2 232 ? 126.124 109.251 168.871 1.00 95.62  ? 222 PHE B CD2 1 
ATOM 3709 C CE1 . PHE B 2 232 ? 123.623 108.128 168.766 1.00 101.63 ? 222 PHE B CE1 1 
ATOM 3710 C CE2 . PHE B 2 232 ? 125.964 107.914 169.138 1.00 100.27 ? 222 PHE B CE2 1 
ATOM 3711 C CZ  . PHE B 2 232 ? 124.710 107.355 169.096 1.00 103.28 ? 222 PHE B CZ  1 
ATOM 3712 N N   . THR B 2 233 ? 125.759 114.730 169.308 1.00 106.35 ? 223 THR B N   1 
ATOM 3713 C CA  . THR B 2 233 ? 125.947 116.085 168.795 1.00 106.74 ? 223 THR B CA  1 
ATOM 3714 C C   . THR B 2 233 ? 127.414 116.232 168.413 1.00 102.00 ? 223 THR B C   1 
ATOM 3715 O O   . THR B 2 233 ? 128.269 116.442 169.278 1.00 109.14 ? 223 THR B O   1 
ATOM 3716 C CB  . THR B 2 233 ? 125.541 117.140 169.825 1.00 117.16 ? 223 THR B CB  1 
ATOM 3717 O OG1 . THR B 2 233 ? 126.336 116.990 171.009 1.00 118.83 ? 223 THR B OG1 1 
ATOM 3718 C CG2 . THR B 2 233 ? 124.066 117.024 170.181 1.00 111.30 ? 223 THR B CG2 1 
ATOM 3719 N N   . GLY B 2 234 ? 127.706 116.116 167.125 1.00 94.73  ? 224 GLY B N   1 
ATOM 3720 C CA  . GLY B 2 234 ? 129.068 116.281 166.668 1.00 103.36 ? 224 GLY B CA  1 
ATOM 3721 C C   . GLY B 2 234 ? 129.169 116.968 165.326 1.00 99.60  ? 224 GLY B C   1 
ATOM 3722 O O   . GLY B 2 234 ? 130.259 117.074 164.759 1.00 101.88 ? 224 GLY B O   1 
ATOM 3723 N N   . HIS B 2 235 ? 128.046 117.444 164.807 1.00 92.15  ? 225 HIS B N   1 
ATOM 3724 C CA  . HIS B 2 235 ? 128.003 118.074 163.499 1.00 87.52  ? 225 HIS B CA  1 
ATOM 3725 C C   . HIS B 2 235 ? 127.799 119.574 163.648 1.00 95.71  ? 225 HIS B C   1 
ATOM 3726 O O   . HIS B 2 235 ? 127.739 120.118 164.754 1.00 102.63 ? 225 HIS B O   1 
ATOM 3727 C CB  . HIS B 2 235 ? 126.905 117.460 162.636 1.00 89.01  ? 225 HIS B CB  1 
ATOM 3728 C CG  . HIS B 2 235 ? 127.386 116.364 161.741 1.00 93.40  ? 225 HIS B CG  1 
ATOM 3729 N ND1 . HIS B 2 235 ? 128.178 116.595 160.638 1.00 94.87  ? 225 HIS B ND1 1 
ATOM 3730 C CD2 . HIS B 2 235 ? 127.194 115.027 161.793 1.00 94.79  ? 225 HIS B CD2 1 
ATOM 3731 C CE1 . HIS B 2 235 ? 128.450 115.446 160.047 1.00 93.51  ? 225 HIS B CE1 1 
ATOM 3732 N NE2 . HIS B 2 235 ? 127.861 114.479 160.724 1.00 93.50  ? 225 HIS B NE2 1 
ATOM 3733 N N   . GLU B 2 236 ? 127.688 120.242 162.505 1.00 93.65  ? 226 GLU B N   1 
ATOM 3734 C CA  . GLU B 2 236 ? 127.667 121.696 162.477 1.00 94.97  ? 226 GLU B CA  1 
ATOM 3735 C C   . GLU B 2 236 ? 126.684 122.256 161.454 1.00 92.41  ? 226 GLU B C   1 
ATOM 3736 O O   . GLU B 2 236 ? 126.579 123.481 161.325 1.00 96.43  ? 226 GLU B O   1 
ATOM 3737 C CB  . GLU B 2 236 ? 129.104 122.183 162.240 1.00 98.89  ? 226 GLU B CB  1 
ATOM 3738 C CG  . GLU B 2 236 ? 129.535 122.261 160.797 1.00 106.42 ? 226 GLU B CG  1 
ATOM 3739 C CD  . GLU B 2 236 ? 130.821 123.035 160.608 1.00 115.93 ? 226 GLU B CD  1 
ATOM 3740 O OE1 . GLU B 2 236 ? 131.290 123.668 161.569 1.00 111.27 ? 226 GLU B OE1 1 
ATOM 3741 O OE2 . GLU B 2 236 ? 131.370 123.006 159.487 1.00 124.94 ? 226 GLU B OE2 1 
ATOM 3742 N N   . SER B 2 237 ? 125.932 121.407 160.761 1.00 88.90  ? 227 SER B N   1 
ATOM 3743 C CA  . SER B 2 237 ? 124.888 121.841 159.844 1.00 89.41  ? 227 SER B CA  1 
ATOM 3744 C C   . SER B 2 237 ? 123.814 120.760 159.802 1.00 93.29  ? 227 SER B C   1 
ATOM 3745 O O   . SER B 2 237 ? 123.819 119.824 160.605 1.00 98.61  ? 227 SER B O   1 
ATOM 3746 C CB  . SER B 2 237 ? 125.463 122.137 158.456 1.00 96.76  ? 227 SER B CB  1 
ATOM 3747 O OG  . SER B 2 237 ? 124.477 122.710 157.616 1.00 101.67 ? 227 SER B OG  1 
ATOM 3748 N N   . ASP B 2 238 ? 122.891 120.890 158.856 1.00 95.47  ? 228 ASP B N   1 
ATOM 3749 C CA  . ASP B 2 238 ? 121.737 120.001 158.786 1.00 98.44  ? 228 ASP B CA  1 
ATOM 3750 C C   . ASP B 2 238 ? 122.124 118.629 158.239 1.00 97.18  ? 228 ASP B C   1 
ATOM 3751 O O   . ASP B 2 238 ? 122.557 118.510 157.089 1.00 100.31 ? 228 ASP B O   1 
ATOM 3752 C CB  . ASP B 2 238 ? 120.648 120.639 157.929 1.00 101.43 ? 228 ASP B CB  1 
ATOM 3753 C CG  . ASP B 2 238 ? 121.200 121.328 156.701 1.00 110.42 ? 228 ASP B CG  1 
ATOM 3754 O OD1 . ASP B 2 238 ? 122.436 121.357 156.549 1.00 111.18 ? 228 ASP B OD1 1 
ATOM 3755 O OD2 . ASP B 2 238 ? 120.401 121.835 155.887 1.00 115.83 ? 228 ASP B OD2 1 
ATOM 3756 N N   . ILE B 2 239 ? 121.936 117.596 159.060 1.00 92.28  ? 229 ILE B N   1 
ATOM 3757 C CA  . ILE B 2 239 ? 122.233 116.211 158.696 1.00 83.56  ? 229 ILE B CA  1 
ATOM 3758 C C   . ILE B 2 239 ? 121.234 115.774 157.631 1.00 84.79  ? 229 ILE B C   1 
ATOM 3759 O O   . ILE B 2 239 ? 120.021 115.898 157.818 1.00 92.20  ? 229 ILE B O   1 
ATOM 3760 C CB  . ILE B 2 239 ? 122.175 115.288 159.917 1.00 83.79  ? 229 ILE B CB  1 
ATOM 3761 C CG1 . ILE B 2 239 ? 123.255 115.677 160.926 1.00 88.47  ? 229 ILE B CG1 1 
ATOM 3762 C CG2 . ILE B 2 239 ? 122.308 113.833 159.490 1.00 81.32  ? 229 ILE B CG2 1 
ATOM 3763 C CD1 . ILE B 2 239 ? 123.485 114.660 162.023 1.00 92.26  ? 229 ILE B CD1 1 
ATOM 3764 N N   . ASN B 2 240 ? 121.737 115.258 156.512 1.00 79.63  ? 230 ASN B N   1 
ATOM 3765 C CA  . ASN B 2 240 ? 120.889 114.934 155.375 1.00 78.96  ? 230 ASN B CA  1 
ATOM 3766 C C   . ASN B 2 240 ? 120.635 113.445 155.218 1.00 83.44  ? 230 ASN B C   1 
ATOM 3767 O O   . ASN B 2 240 ? 119.548 113.054 154.780 1.00 90.44  ? 230 ASN B O   1 
ATOM 3768 C CB  . ASN B 2 240 ? 121.522 115.464 154.091 1.00 82.53  ? 230 ASN B CB  1 
ATOM 3769 C CG  . ASN B 2 240 ? 120.819 116.681 153.556 1.00 92.05  ? 230 ASN B CG  1 
ATOM 3770 O OD1 . ASN B 2 240 ? 119.632 116.874 153.784 1.00 98.29  ? 230 ASN B OD1 1 
ATOM 3771 N ND2 . ASN B 2 240 ? 121.552 117.513 152.828 1.00 95.72  ? 230 ASN B ND2 1 
ATOM 3772 N N   . ALA B 2 241 ? 121.606 112.605 155.558 1.00 82.03  ? 231 ALA B N   1 
ATOM 3773 C CA  . ALA B 2 241 ? 121.490 111.178 155.318 1.00 75.05  ? 231 ALA B CA  1 
ATOM 3774 C C   . ALA B 2 241 ? 122.132 110.409 156.458 1.00 75.38  ? 231 ALA B C   1 
ATOM 3775 O O   . ALA B 2 241 ? 122.995 110.921 157.173 1.00 82.89  ? 231 ALA B O   1 
ATOM 3776 C CB  . ALA B 2 241 ? 122.137 110.778 153.992 1.00 79.65  ? 231 ALA B CB  1 
ATOM 3777 N N   . ILE B 2 242 ? 121.699 109.161 156.615 1.00 72.82  ? 232 ILE B N   1 
ATOM 3778 C CA  . ILE B 2 242 ? 122.170 108.310 157.697 1.00 73.96  ? 232 ILE B CA  1 
ATOM 3779 C C   . ILE B 2 242 ? 122.043 106.861 157.247 1.00 81.74  ? 232 ILE B C   1 
ATOM 3780 O O   . ILE B 2 242 ? 121.192 106.524 156.418 1.00 89.75  ? 232 ILE B O   1 
ATOM 3781 C CB  . ILE B 2 242 ? 121.388 108.617 158.998 1.00 72.78  ? 232 ILE B CB  1 
ATOM 3782 C CG1 . ILE B 2 242 ? 122.248 108.370 160.227 1.00 76.01  ? 232 ILE B CG1 1 
ATOM 3783 C CG2 . ILE B 2 242 ? 120.088 107.828 159.094 1.00 79.56  ? 232 ILE B CG2 1 
ATOM 3784 C CD1 . ILE B 2 242 ? 121.684 109.036 161.439 1.00 85.04  ? 232 ILE B CD1 1 
ATOM 3785 N N   . CYS B 2 243 ? 122.933 106.010 157.761 1.00 78.60  ? 233 CYS B N   1 
ATOM 3786 C CA  . CYS B 2 243 ? 122.928 104.595 157.414 1.00 78.16  ? 233 CYS B CA  1 
ATOM 3787 C C   . CYS B 2 243 ? 123.755 103.827 158.437 1.00 78.93  ? 233 CYS B C   1 
ATOM 3788 O O   . CYS B 2 243 ? 124.865 104.239 158.779 1.00 82.89  ? 233 CYS B O   1 
ATOM 3789 C CB  . CYS B 2 243 ? 123.476 104.361 156.000 1.00 83.71  ? 233 CYS B CB  1 
ATOM 3790 S SG  . CYS B 2 243 ? 124.178 102.734 155.697 1.00 111.55 ? 233 CYS B SG  1 
ATOM 3791 N N   . PHE B 2 244 ? 123.210 102.710 158.907 1.00 77.27  ? 234 PHE B N   1 
ATOM 3792 C CA  . PHE B 2 244 ? 123.857 101.885 159.916 1.00 82.50  ? 234 PHE B CA  1 
ATOM 3793 C C   . PHE B 2 244 ? 125.064 101.146 159.353 1.00 89.57  ? 234 PHE B C   1 
ATOM 3794 O O   . PHE B 2 244 ? 125.197 100.953 158.143 1.00 90.87  ? 234 PHE B O   1 
ATOM 3795 C CB  . PHE B 2 244 ? 122.883 100.845 160.466 1.00 85.28  ? 234 PHE B CB  1 
ATOM 3796 C CG  . PHE B 2 244 ? 122.444 101.088 161.879 1.00 88.13  ? 234 PHE B CG  1 
ATOM 3797 C CD1 . PHE B 2 244 ? 121.543 102.084 162.186 1.00 86.56  ? 234 PHE B CD1 1 
ATOM 3798 C CD2 . PHE B 2 244 ? 122.938 100.304 162.905 1.00 91.84  ? 234 PHE B CD2 1 
ATOM 3799 C CE1 . PHE B 2 244 ? 121.138 102.281 163.488 1.00 85.31  ? 234 PHE B CE1 1 
ATOM 3800 C CE2 . PHE B 2 244 ? 122.541 100.508 164.207 1.00 89.84  ? 234 PHE B CE2 1 
ATOM 3801 C CZ  . PHE B 2 244 ? 121.643 101.500 164.497 1.00 82.46  ? 234 PHE B CZ  1 
ATOM 3802 N N   . PHE B 2 245 ? 125.944 100.720 160.255 1.00 95.12  ? 235 PHE B N   1 
ATOM 3803 C CA  . PHE B 2 245 ? 126.887 99.665  159.926 1.00 93.20  ? 235 PHE B CA  1 
ATOM 3804 C C   . PHE B 2 245 ? 126.135 98.353  159.711 1.00 94.89  ? 235 PHE B C   1 
ATOM 3805 O O   . PHE B 2 245 ? 125.039 98.165  160.245 1.00 100.07 ? 235 PHE B O   1 
ATOM 3806 C CB  . PHE B 2 245 ? 127.913 99.476  161.043 1.00 90.01  ? 235 PHE B CB  1 
ATOM 3807 C CG  . PHE B 2 245 ? 129.335 99.450  160.565 1.00 90.52  ? 235 PHE B CG  1 
ATOM 3808 C CD1 . PHE B 2 245 ? 129.950 100.591 160.095 1.00 91.63  ? 235 PHE B CD1 1 
ATOM 3809 C CD2 . PHE B 2 245 ? 130.037 98.259  160.538 1.00 95.31  ? 235 PHE B CD2 1 
ATOM 3810 C CE1 . PHE B 2 245 ? 131.259 100.549 159.650 1.00 96.06  ? 235 PHE B CE1 1 
ATOM 3811 C CE2 . PHE B 2 245 ? 131.333 98.208  160.071 1.00 96.10  ? 235 PHE B CE2 1 
ATOM 3812 C CZ  . PHE B 2 245 ? 131.947 99.356  159.634 1.00 95.57  ? 235 PHE B CZ  1 
ATOM 3813 N N   . PRO B 2 246 ? 126.693 97.435  158.917 1.00 90.49  ? 236 PRO B N   1 
ATOM 3814 C CA  . PRO B 2 246 ? 126.114 96.083  158.855 1.00 92.55  ? 236 PRO B CA  1 
ATOM 3815 C C   . PRO B 2 246 ? 126.151 95.338  160.179 1.00 94.07  ? 236 PRO B C   1 
ATOM 3816 O O   . PRO B 2 246 ? 125.321 94.448  160.398 1.00 97.47  ? 236 PRO B O   1 
ATOM 3817 C CB  . PRO B 2 246 ? 126.969 95.385  157.786 1.00 87.61  ? 236 PRO B CB  1 
ATOM 3818 C CG  . PRO B 2 246 ? 128.202 96.221  157.660 1.00 88.66  ? 236 PRO B CG  1 
ATOM 3819 C CD  . PRO B 2 246 ? 127.753 97.618  157.915 1.00 88.96  ? 236 PRO B CD  1 
ATOM 3820 N N   . ASN B 2 247 ? 127.081 95.672  161.072 1.00 90.66  ? 237 ASN B N   1 
ATOM 3821 C CA  . ASN B 2 247 ? 127.129 95.017  162.372 1.00 92.99  ? 237 ASN B CA  1 
ATOM 3822 C C   . ASN B 2 247 ? 126.116 95.585  163.362 1.00 93.81  ? 237 ASN B C   1 
ATOM 3823 O O   . ASN B 2 247 ? 125.687 94.863  164.267 1.00 91.05  ? 237 ASN B O   1 
ATOM 3824 C CB  . ASN B 2 247 ? 128.603 95.004  162.863 1.00 94.20  ? 237 ASN B CB  1 
ATOM 3825 C CG  . ASN B 2 247 ? 129.082 96.285  163.608 1.00 99.17  ? 237 ASN B CG  1 
ATOM 3826 O OD1 . ASN B 2 247 ? 128.384 96.943  164.373 1.00 100.02 ? 237 ASN B OD1 1 
ATOM 3827 N ND2 . ASN B 2 247 ? 130.343 96.618  163.357 1.00 100.52 ? 237 ASN B ND2 1 
ATOM 3828 N N   . GLY B 2 248 ? 125.725 96.846  163.212 1.00 97.04  ? 238 GLY B N   1 
ATOM 3829 C CA  . GLY B 2 248 ? 124.708 97.414  164.072 1.00 95.45  ? 238 GLY B CA  1 
ATOM 3830 C C   . GLY B 2 248 ? 125.198 98.107  165.322 1.00 99.57  ? 238 GLY B C   1 
ATOM 3831 O O   . GLY B 2 248 ? 124.406 98.318  166.244 1.00 102.53 ? 238 GLY B O   1 
ATOM 3832 N N   . ASN B 2 249 ? 126.477 98.474  165.390 1.00 98.12  ? 239 ASN B N   1 
ATOM 3833 C CA  . ASN B 2 249 ? 127.014 99.183  166.545 1.00 94.59  ? 239 ASN B CA  1 
ATOM 3834 C C   . ASN B 2 249 ? 127.641 100.518 166.170 1.00 94.04  ? 239 ASN B C   1 
ATOM 3835 O O   . ASN B 2 249 ? 128.324 101.127 167.001 1.00 95.28  ? 239 ASN B O   1 
ATOM 3836 C CB  . ASN B 2 249 ? 128.036 98.313  167.277 1.00 92.34  ? 239 ASN B CB  1 
ATOM 3837 C CG  . ASN B 2 249 ? 127.387 97.215  168.081 1.00 101.70 ? 239 ASN B CG  1 
ATOM 3838 O OD1 . ASN B 2 249 ? 126.284 97.379  168.601 1.00 108.60 ? 239 ASN B OD1 1 
ATOM 3839 N ND2 . ASN B 2 249 ? 128.061 96.077  168.178 1.00 102.95 ? 239 ASN B ND2 1 
ATOM 3840 N N   . ALA B 2 250 ? 127.430 100.984 164.943 1.00 94.34  ? 240 ALA B N   1 
ATOM 3841 C CA  . ALA B 2 250 ? 127.950 102.265 164.491 1.00 89.29  ? 240 ALA B CA  1 
ATOM 3842 C C   . ALA B 2 250 ? 127.085 102.746 163.339 1.00 88.29  ? 240 ALA B C   1 
ATOM 3843 O O   . ALA B 2 250 ? 126.368 101.964 162.711 1.00 94.30  ? 240 ALA B O   1 
ATOM 3844 C CB  . ALA B 2 250 ? 129.415 102.160 164.061 1.00 91.49  ? 240 ALA B CB  1 
ATOM 3845 N N   . PHE B 2 251 ? 127.159 104.044 163.071 1.00 83.38  ? 241 PHE B N   1 
ATOM 3846 C CA  . PHE B 2 251 ? 126.413 104.628 161.966 1.00 82.42  ? 241 PHE B CA  1 
ATOM 3847 C C   . PHE B 2 251 ? 127.110 105.899 161.518 1.00 82.47  ? 241 PHE B C   1 
ATOM 3848 O O   . PHE B 2 251 ? 127.775 106.571 162.311 1.00 93.68  ? 241 PHE B O   1 
ATOM 3849 C CB  . PHE B 2 251 ? 124.957 104.918 162.346 1.00 88.40  ? 241 PHE B CB  1 
ATOM 3850 C CG  . PHE B 2 251 ? 124.790 106.002 163.372 1.00 94.46  ? 241 PHE B CG  1 
ATOM 3851 C CD1 . PHE B 2 251 ? 125.008 105.748 164.713 1.00 98.43  ? 241 PHE B CD1 1 
ATOM 3852 C CD2 . PHE B 2 251 ? 124.392 107.269 162.998 1.00 93.36  ? 241 PHE B CD2 1 
ATOM 3853 C CE1 . PHE B 2 251 ? 124.846 106.741 165.653 1.00 98.07  ? 241 PHE B CE1 1 
ATOM 3854 C CE2 . PHE B 2 251 ? 124.228 108.261 163.936 1.00 95.70  ? 241 PHE B CE2 1 
ATOM 3855 C CZ  . PHE B 2 251 ? 124.456 107.997 165.262 1.00 97.70  ? 241 PHE B CZ  1 
ATOM 3856 N N   . ALA B 2 252 ? 126.952 106.221 160.239 1.00 77.25  ? 242 ALA B N   1 
ATOM 3857 C CA  . ALA B 2 252 ? 127.579 107.390 159.645 1.00 83.33  ? 242 ALA B CA  1 
ATOM 3858 C C   . ALA B 2 252 ? 126.514 108.334 159.118 1.00 80.82  ? 242 ALA B C   1 
ATOM 3859 O O   . ALA B 2 252 ? 125.570 107.903 158.449 1.00 85.50  ? 242 ALA B O   1 
ATOM 3860 C CB  . ALA B 2 252 ? 128.535 107.005 158.520 1.00 89.17  ? 242 ALA B CB  1 
ATOM 3861 N N   . THR B 2 253 ? 126.671 109.614 159.424 1.00 81.42  ? 243 THR B N   1 
ATOM 3862 C CA  . THR B 2 253 ? 125.779 110.657 158.957 1.00 86.21  ? 243 THR B CA  1 
ATOM 3863 C C   . THR B 2 253 ? 126.543 111.591 158.034 1.00 84.80  ? 243 THR B C   1 
ATOM 3864 O O   . THR B 2 253 ? 127.762 111.741 158.139 1.00 88.62  ? 243 THR B O   1 
ATOM 3865 C CB  . THR B 2 253 ? 125.194 111.469 160.117 1.00 95.93  ? 243 THR B CB  1 
ATOM 3866 O OG1 . THR B 2 253 ? 126.071 112.558 160.415 1.00 102.06 ? 243 THR B OG1 1 
ATOM 3867 C CG2 . THR B 2 253 ? 125.051 110.612 161.357 1.00 93.09  ? 243 THR B CG2 1 
ATOM 3868 N N   . GLY B 2 254 ? 125.814 112.224 157.127 1.00 82.99  ? 244 GLY B N   1 
ATOM 3869 C CA  . GLY B 2 254 ? 126.421 113.202 156.253 1.00 85.50  ? 244 GLY B CA  1 
ATOM 3870 C C   . GLY B 2 254 ? 125.560 114.433 156.084 1.00 87.57  ? 244 GLY B C   1 
ATOM 3871 O O   . GLY B 2 254 ? 124.409 114.340 155.650 1.00 91.00  ? 244 GLY B O   1 
ATOM 3872 N N   . SER B 2 255 ? 126.108 115.591 156.417 1.00 87.20  ? 245 SER B N   1 
ATOM 3873 C CA  . SER B 2 255 ? 125.368 116.840 156.446 1.00 93.63  ? 245 SER B CA  1 
ATOM 3874 C C   . SER B 2 255 ? 125.789 117.739 155.290 1.00 93.40  ? 245 SER B C   1 
ATOM 3875 O O   . SER B 2 255 ? 126.619 117.375 154.453 1.00 96.79  ? 245 SER B O   1 
ATOM 3876 C CB  . SER B 2 255 ? 125.569 117.537 157.791 1.00 97.28  ? 245 SER B CB  1 
ATOM 3877 O OG  . SER B 2 255 ? 126.890 117.353 158.247 1.00 100.52 ? 245 SER B OG  1 
ATOM 3878 N N   . ASP B 2 256 ? 125.204 118.935 155.256 1.00 93.54  ? 246 ASP B N   1 
ATOM 3879 C CA  . ASP B 2 256 ? 125.511 119.924 154.232 1.00 93.88  ? 246 ASP B CA  1 
ATOM 3880 C C   . ASP B 2 256 ? 126.745 120.747 154.558 1.00 95.34  ? 246 ASP B C   1 
ATOM 3881 O O   . ASP B 2 256 ? 127.038 121.705 153.835 1.00 102.07 ? 246 ASP B O   1 
ATOM 3882 C CB  . ASP B 2 256 ? 124.324 120.860 154.014 1.00 92.54  ? 246 ASP B CB  1 
ATOM 3883 C CG  . ASP B 2 256 ? 123.208 120.214 153.223 1.00 103.08 ? 246 ASP B CG  1 
ATOM 3884 O OD1 . ASP B 2 256 ? 123.485 119.252 152.477 1.00 101.56 ? 246 ASP B OD1 1 
ATOM 3885 O OD2 . ASP B 2 256 ? 122.052 120.671 153.342 1.00 111.14 ? 246 ASP B OD2 1 
ATOM 3886 N N   . ASP B 2 257 ? 127.474 120.404 155.617 1.00 87.70  ? 247 ASP B N   1 
ATOM 3887 C CA  . ASP B 2 257 ? 128.745 121.041 155.921 1.00 86.42  ? 247 ASP B CA  1 
ATOM 3888 C C   . ASP B 2 257 ? 129.910 120.422 155.166 1.00 93.62  ? 247 ASP B C   1 
ATOM 3889 O O   . ASP B 2 257 ? 131.062 120.637 155.559 1.00 98.75  ? 247 ASP B O   1 
ATOM 3890 C CB  . ASP B 2 257 ? 129.018 120.995 157.424 1.00 90.50  ? 247 ASP B CB  1 
ATOM 3891 C CG  . ASP B 2 257 ? 128.909 119.597 158.005 1.00 98.46  ? 247 ASP B CG  1 
ATOM 3892 O OD1 . ASP B 2 257 ? 128.969 119.465 159.244 1.00 102.46 ? 247 ASP B OD1 1 
ATOM 3893 O OD2 . ASP B 2 257 ? 128.724 118.622 157.247 1.00 101.35 ? 247 ASP B OD2 1 
ATOM 3894 N N   . ALA B 2 258 ? 129.624 119.633 154.126 1.00 92.40  ? 248 ALA B N   1 
ATOM 3895 C CA  . ALA B 2 258 ? 130.597 118.953 153.273 1.00 91.97  ? 248 ALA B CA  1 
ATOM 3896 C C   . ALA B 2 258 ? 131.471 117.969 154.044 1.00 90.23  ? 248 ALA B C   1 
ATOM 3897 O O   . ALA B 2 258 ? 132.569 117.630 153.599 1.00 92.17  ? 248 ALA B O   1 
ATOM 3898 C CB  . ALA B 2 258 ? 131.466 119.957 152.503 1.00 94.85  ? 248 ALA B CB  1 
ATOM 3899 N N   . THR B 2 259 ? 131.007 117.493 155.195 1.00 90.11  ? 249 THR B N   1 
ATOM 3900 C CA  . THR B 2 259 ? 131.743 116.531 155.999 1.00 88.20  ? 249 THR B CA  1 
ATOM 3901 C C   . THR B 2 259 ? 130.860 115.331 156.288 1.00 89.03  ? 249 THR B C   1 
ATOM 3902 O O   . THR B 2 259 ? 129.646 115.467 156.464 1.00 90.80  ? 249 THR B O   1 
ATOM 3903 C CB  . THR B 2 259 ? 132.228 117.126 157.331 1.00 93.41  ? 249 THR B CB  1 
ATOM 3904 O OG1 . THR B 2 259 ? 131.106 117.370 158.187 1.00 100.96 ? 249 THR B OG1 1 
ATOM 3905 C CG2 . THR B 2 259 ? 133.004 118.420 157.119 1.00 93.49  ? 249 THR B CG2 1 
ATOM 3906 N N   . CYS B 2 260 ? 131.478 114.157 156.334 1.00 87.55  ? 250 CYS B N   1 
ATOM 3907 C CA  . CYS B 2 260 ? 130.819 112.922 156.727 1.00 83.26  ? 250 CYS B CA  1 
ATOM 3908 C C   . CYS B 2 260 ? 131.463 112.429 158.013 1.00 80.50  ? 250 CYS B C   1 
ATOM 3909 O O   . CYS B 2 260 ? 132.693 112.401 158.122 1.00 85.83  ? 250 CYS B O   1 
ATOM 3910 C CB  . CYS B 2 260 ? 130.930 111.866 155.628 1.00 86.06  ? 250 CYS B CB  1 
ATOM 3911 S SG  . CYS B 2 260 ? 129.592 110.660 155.609 1.00 100.66 ? 250 CYS B SG  1 
ATOM 3912 N N   . ARG B 2 261 ? 130.639 112.055 158.982 1.00 75.10  ? 251 ARG B N   1 
ATOM 3913 C CA  . ARG B 2 261 ? 131.114 111.687 160.305 1.00 77.35  ? 251 ARG B CA  1 
ATOM 3914 C C   . ARG B 2 261 ? 130.556 110.326 160.685 1.00 82.34  ? 251 ARG B C   1 
ATOM 3915 O O   . ARG B 2 261 ? 129.402 110.017 160.383 1.00 90.03  ? 251 ARG B O   1 
ATOM 3916 C CB  . ARG B 2 261 ? 130.699 112.739 161.333 1.00 86.31  ? 251 ARG B CB  1 
ATOM 3917 C CG  . ARG B 2 261 ? 131.770 113.773 161.619 1.00 91.49  ? 251 ARG B CG  1 
ATOM 3918 C CD  . ARG B 2 261 ? 131.411 114.629 162.827 1.00 94.29  ? 251 ARG B CD  1 
ATOM 3919 N NE  . ARG B 2 261 ? 132.286 115.785 162.994 1.00 94.43  ? 251 ARG B NE  1 
ATOM 3920 C CZ  . ARG B 2 261 ? 132.301 116.856 162.210 1.00 95.16  ? 251 ARG B CZ  1 
ATOM 3921 N NH1 . ARG B 2 261 ? 131.439 117.005 161.218 1.00 98.74  ? 251 ARG B NH1 1 
ATOM 3922 N NH2 . ARG B 2 261 ? 133.193 117.814 162.441 1.00 91.44  ? 251 ARG B NH2 1 
ATOM 3923 N N   . LEU B 2 262 ? 131.373 109.519 161.354 1.00 82.94  ? 252 LEU B N   1 
ATOM 3924 C CA  . LEU B 2 262 ? 130.985 108.182 161.777 1.00 81.51  ? 252 LEU B CA  1 
ATOM 3925 C C   . LEU B 2 262 ? 130.925 108.160 163.295 1.00 84.31  ? 252 LEU B C   1 
ATOM 3926 O O   . LEU B 2 262 ? 131.901 108.513 163.964 1.00 92.30  ? 252 LEU B O   1 
ATOM 3927 C CB  . LEU B 2 262 ? 131.975 107.134 161.255 1.00 85.74  ? 252 LEU B CB  1 
ATOM 3928 C CG  . LEU B 2 262 ? 132.240 105.824 162.003 1.00 88.68  ? 252 LEU B CG  1 
ATOM 3929 C CD1 . LEU B 2 262 ? 130.997 104.940 162.062 1.00 88.37  ? 252 LEU B CD1 1 
ATOM 3930 C CD2 . LEU B 2 262 ? 133.396 105.075 161.365 1.00 92.00  ? 252 LEU B CD2 1 
ATOM 3931 N N   . PHE B 2 263 ? 129.784 107.749 163.833 1.00 82.10  ? 253 PHE B N   1 
ATOM 3932 C CA  . PHE B 2 263 ? 129.555 107.715 165.267 1.00 83.68  ? 253 PHE B CA  1 
ATOM 3933 C C   . PHE B 2 263 ? 129.530 106.273 165.748 1.00 88.88  ? 253 PHE B C   1 
ATOM 3934 O O   . PHE B 2 263 ? 129.389 105.336 164.960 1.00 96.17  ? 253 PHE B O   1 
ATOM 3935 C CB  . PHE B 2 263 ? 128.242 108.407 165.653 1.00 86.11  ? 253 PHE B CB  1 
ATOM 3936 C CG  . PHE B 2 263 ? 128.229 109.889 165.406 1.00 90.58  ? 253 PHE B CG  1 
ATOM 3937 C CD1 . PHE B 2 263 ? 128.253 110.771 166.469 1.00 98.57  ? 253 PHE B CD1 1 
ATOM 3938 C CD2 . PHE B 2 263 ? 128.130 110.400 164.124 1.00 89.22  ? 253 PHE B CD2 1 
ATOM 3939 C CE1 . PHE B 2 263 ? 128.231 112.132 166.257 1.00 104.98 ? 253 PHE B CE1 1 
ATOM 3940 C CE2 . PHE B 2 263 ? 128.105 111.757 163.905 1.00 93.74  ? 253 PHE B CE2 1 
ATOM 3941 C CZ  . PHE B 2 263 ? 128.153 112.625 164.973 1.00 103.49 ? 253 PHE B CZ  1 
ATOM 3942 N N   . ASP B 2 264 ? 129.663 106.101 167.058 1.00 88.47  ? 254 ASP B N   1 
ATOM 3943 C CA  . ASP B 2 264 ? 129.688 104.784 167.670 1.00 92.94  ? 254 ASP B CA  1 
ATOM 3944 C C   . ASP B 2 264 ? 128.623 104.771 168.758 1.00 97.28  ? 254 ASP B C   1 
ATOM 3945 O O   . ASP B 2 264 ? 128.512 105.714 169.546 1.00 99.00  ? 254 ASP B O   1 
ATOM 3946 C CB  . ASP B 2 264 ? 131.107 104.481 168.213 1.00 98.77  ? 254 ASP B CB  1 
ATOM 3947 C CG  . ASP B 2 264 ? 131.148 103.480 169.384 1.00 107.18 ? 254 ASP B CG  1 
ATOM 3948 O OD1 . ASP B 2 264 ? 130.298 102.570 169.535 1.00 107.70 ? 254 ASP B OD1 1 
ATOM 3949 O OD2 . ASP B 2 264 ? 132.077 103.629 170.193 1.00 114.03 ? 254 ASP B OD2 1 
ATOM 3950 N N   . LEU B 2 265 ? 127.848 103.687 168.793 1.00 98.41  ? 255 LEU B N   1 
ATOM 3951 C CA  . LEU B 2 265 ? 126.754 103.558 169.748 1.00 94.17  ? 255 LEU B CA  1 
ATOM 3952 C C   . LEU B 2 265 ? 127.246 103.316 171.166 1.00 93.78  ? 255 LEU B C   1 
ATOM 3953 O O   . LEU B 2 265 ? 126.576 103.713 172.124 1.00 95.27  ? 255 LEU B O   1 
ATOM 3954 C CB  . LEU B 2 265 ? 125.831 102.410 169.337 1.00 98.41  ? 255 LEU B CB  1 
ATOM 3955 C CG  . LEU B 2 265 ? 124.968 102.527 168.080 1.00 101.60 ? 255 LEU B CG  1 
ATOM 3956 C CD1 . LEU B 2 265 ? 123.777 101.586 168.177 1.00 101.89 ? 255 LEU B CD1 1 
ATOM 3957 C CD2 . LEU B 2 265 ? 124.501 103.951 167.888 1.00 98.45  ? 255 LEU B CD2 1 
ATOM 3958 N N   . ARG B 2 266 ? 128.401 102.675 171.320 1.00 97.17  ? 256 ARG B N   1 
ATOM 3959 C CA  . ARG B 2 266 ? 128.821 102.148 172.612 1.00 95.77  ? 256 ARG B CA  1 
ATOM 3960 C C   . ARG B 2 266 ? 129.641 103.137 173.433 1.00 93.34  ? 256 ARG B C   1 
ATOM 3961 O O   . ARG B 2 266 ? 129.520 103.163 174.661 1.00 90.82  ? 256 ARG B O   1 
ATOM 3962 C CB  . ARG B 2 266 ? 129.606 100.856 172.400 1.00 96.24  ? 256 ARG B CB  1 
ATOM 3963 C CG  . ARG B 2 266 ? 128.742 99.696  171.951 1.00 99.10  ? 256 ARG B CG  1 
ATOM 3964 C CD  . ARG B 2 266 ? 129.550 98.422  171.824 1.00 108.66 ? 256 ARG B CD  1 
ATOM 3965 N NE  . ARG B 2 266 ? 128.709 97.273  171.516 1.00 116.92 ? 256 ARG B NE  1 
ATOM 3966 C CZ  . ARG B 2 266 ? 129.168 96.052  171.281 1.00 117.82 ? 256 ARG B CZ  1 
ATOM 3967 N NH1 . ARG B 2 266 ? 130.465 95.791  171.278 1.00 116.96 ? 256 ARG B NH1 1 
ATOM 3968 N NH2 . ARG B 2 266 ? 128.305 95.068  171.049 1.00 116.20 ? 256 ARG B NH2 1 
ATOM 3969 N N   . ALA B 2 267 ? 130.481 103.950 172.794 1.00 93.31  ? 257 ALA B N   1 
ATOM 3970 C CA  . ALA B 2 267 ? 131.224 104.964 173.528 1.00 101.21 ? 257 ALA B CA  1 
ATOM 3971 C C   . ALA B 2 267 ? 130.558 106.329 173.488 1.00 110.92 ? 257 ALA B C   1 
ATOM 3972 O O   . ALA B 2 267 ? 130.985 107.225 174.227 1.00 120.61 ? 257 ALA B O   1 
ATOM 3973 C CB  . ALA B 2 267 ? 132.651 105.087 172.992 1.00 101.65 ? 257 ALA B CB  1 
ATOM 3974 N N   . ASP B 2 268 ? 129.530 106.489 172.648 1.00 104.47 ? 258 ASP B N   1 
ATOM 3975 C CA  . ASP B 2 268 ? 128.727 107.708 172.516 1.00 108.85 ? 258 ASP B CA  1 
ATOM 3976 C C   . ASP B 2 268 ? 129.623 108.901 172.153 1.00 111.17 ? 258 ASP B C   1 
ATOM 3977 O O   . ASP B 2 268 ? 129.560 109.984 172.737 1.00 115.42 ? 258 ASP B O   1 
ATOM 3978 C CB  . ASP B 2 268 ? 127.901 107.942 173.795 1.00 112.79 ? 258 ASP B CB  1 
ATOM 3979 C CG  . ASP B 2 268 ? 126.900 109.085 173.671 1.00 118.91 ? 258 ASP B CG  1 
ATOM 3980 O OD1 . ASP B 2 268 ? 126.617 109.518 172.534 1.00 118.46 ? 258 ASP B OD1 1 
ATOM 3981 O OD2 . ASP B 2 268 ? 126.393 109.547 174.715 1.00 119.71 ? 258 ASP B OD2 1 
ATOM 3982 N N   . GLN B 2 269 ? 130.504 108.660 171.183 1.00 104.86 ? 259 GLN B N   1 
ATOM 3983 C CA  . GLN B 2 269 ? 131.395 109.692 170.673 1.00 96.89  ? 259 GLN B CA  1 
ATOM 3984 C C   . GLN B 2 269 ? 131.494 109.560 169.163 1.00 93.97  ? 259 GLN B C   1 
ATOM 3985 O O   . GLN B 2 269 ? 131.302 108.479 168.601 1.00 99.10  ? 259 GLN B O   1 
ATOM 3986 C CB  . GLN B 2 269 ? 132.802 109.605 171.279 1.00 96.03  ? 259 GLN B CB  1 
ATOM 3987 C CG  . GLN B 2 269 ? 132.878 109.828 172.771 1.00 105.14 ? 259 GLN B CG  1 
ATOM 3988 C CD  . GLN B 2 269 ? 134.297 109.853 173.284 1.00 116.70 ? 259 GLN B CD  1 
ATOM 3989 O OE1 . GLN B 2 269 ? 135.095 110.700 172.888 1.00 123.91 ? 259 GLN B OE1 1 
ATOM 3990 N NE2 . GLN B 2 269 ? 134.621 108.926 174.178 1.00 121.78 ? 259 GLN B NE2 1 
ATOM 3991 N N   . GLU B 2 270 ? 131.798 110.676 168.513 1.00 92.61  ? 260 GLU B N   1 
ATOM 3992 C CA  . GLU B 2 270 ? 132.164 110.644 167.105 1.00 92.39  ? 260 GLU B CA  1 
ATOM 3993 C C   . GLU B 2 270 ? 133.534 109.996 166.964 1.00 93.17  ? 260 GLU B C   1 
ATOM 3994 O O   . GLU B 2 270 ? 134.475 110.351 167.680 1.00 103.08 ? 260 GLU B O   1 
ATOM 3995 C CB  . GLU B 2 270 ? 132.112 112.069 166.532 1.00 96.25  ? 260 GLU B CB  1 
ATOM 3996 C CG  . GLU B 2 270 ? 132.920 112.445 165.270 1.00 101.02 ? 260 GLU B CG  1 
ATOM 3997 C CD  . GLU B 2 270 ? 134.415 112.647 165.490 1.00 110.51 ? 260 GLU B CD  1 
ATOM 3998 O OE1 . GLU B 2 270 ? 134.787 113.526 166.296 1.00 113.97 ? 260 GLU B OE1 1 
ATOM 3999 O OE2 . GLU B 2 270 ? 135.213 111.944 164.838 1.00 109.75 ? 260 GLU B OE2 1 
ATOM 4000 N N   . LEU B 2 271 ? 133.647 109.035 166.050 1.00 87.54  ? 261 LEU B N   1 
ATOM 4001 C CA  . LEU B 2 271 ? 134.887 108.278 165.922 1.00 91.47  ? 261 LEU B CA  1 
ATOM 4002 C C   . LEU B 2 271 ? 135.844 108.930 164.930 1.00 93.28  ? 261 LEU B C   1 
ATOM 4003 O O   . LEU B 2 271 ? 136.936 109.366 165.308 1.00 95.74  ? 261 LEU B O   1 
ATOM 4004 C CB  . LEU B 2 271 ? 134.581 106.835 165.505 1.00 94.69  ? 261 LEU B CB  1 
ATOM 4005 C CG  . LEU B 2 271 ? 134.732 105.732 166.558 1.00 96.75  ? 261 LEU B CG  1 
ATOM 4006 C CD1 . LEU B 2 271 ? 134.986 104.383 165.894 1.00 99.07  ? 261 LEU B CD1 1 
ATOM 4007 C CD2 . LEU B 2 271 ? 135.827 106.051 167.567 1.00 92.84  ? 261 LEU B CD2 1 
ATOM 4008 N N   . MET B 2 272 ? 135.439 109.034 163.667 1.00 91.02  ? 262 MET B N   1 
ATOM 4009 C CA  . MET B 2 272 ? 136.329 109.525 162.626 1.00 93.93  ? 262 MET B CA  1 
ATOM 4010 C C   . MET B 2 272 ? 135.542 110.361 161.633 1.00 90.49  ? 262 MET B C   1 
ATOM 4011 O O   . MET B 2 272 ? 134.471 109.947 161.183 1.00 92.10  ? 262 MET B O   1 
ATOM 4012 C CB  . MET B 2 272 ? 137.023 108.359 161.913 1.00 97.87  ? 262 MET B CB  1 
ATOM 4013 C CG  . MET B 2 272 ? 137.614 108.695 160.560 1.00 102.88 ? 262 MET B CG  1 
ATOM 4014 S SD  . MET B 2 272 ? 139.276 109.393 160.653 1.00 131.34 ? 262 MET B SD  1 
ATOM 4015 C CE  . MET B 2 272 ? 139.948 108.551 162.085 1.00 113.24 ? 262 MET B CE  1 
ATOM 4016 N N   . THR B 2 273 ? 136.070 111.532 161.298 1.00 86.13  ? 263 THR B N   1 
ATOM 4017 C CA  . THR B 2 273 ? 135.493 112.373 160.264 1.00 86.63  ? 263 THR B CA  1 
ATOM 4018 C C   . THR B 2 273 ? 136.307 112.265 158.981 1.00 83.66  ? 263 THR B C   1 
ATOM 4019 O O   . THR B 2 273 ? 137.485 111.901 158.994 1.00 86.70  ? 263 THR B O   1 
ATOM 4020 C CB  . THR B 2 273 ? 135.410 113.833 160.721 1.00 90.26  ? 263 THR B CB  1 
ATOM 4021 O OG1 . THR B 2 273 ? 134.577 114.571 159.818 1.00 97.10  ? 263 THR B OG1 1 
ATOM 4022 C CG2 . THR B 2 273 ? 136.787 114.478 160.788 1.00 87.96  ? 263 THR B CG2 1 
ATOM 4023 N N   . TYR B 2 274 ? 135.646 112.540 157.862 1.00 80.49  ? 264 TYR B N   1 
ATOM 4024 C CA  . TYR B 2 274 ? 136.276 112.550 156.551 1.00 84.48  ? 264 TYR B CA  1 
ATOM 4025 C C   . TYR B 2 274 ? 136.109 113.931 155.943 1.00 88.21  ? 264 TYR B C   1 
ATOM 4026 O O   . TYR B 2 274 ? 134.987 114.439 155.852 1.00 89.37  ? 264 TYR B O   1 
ATOM 4027 C CB  . TYR B 2 274 ? 135.665 111.494 155.630 1.00 87.98  ? 264 TYR B CB  1 
ATOM 4028 C CG  . TYR B 2 274 ? 135.204 110.240 156.332 1.00 88.25  ? 264 TYR B CG  1 
ATOM 4029 C CD1 . TYR B 2 274 ? 136.111 109.391 156.942 1.00 90.07  ? 264 TYR B CD1 1 
ATOM 4030 C CD2 . TYR B 2 274 ? 133.862 109.897 156.367 1.00 90.12  ? 264 TYR B CD2 1 
ATOM 4031 C CE1 . TYR B 2 274 ? 135.695 108.243 157.575 1.00 91.68  ? 264 TYR B CE1 1 
ATOM 4032 C CE2 . TYR B 2 274 ? 133.437 108.750 156.999 1.00 90.58  ? 264 TYR B CE2 1 
ATOM 4033 C CZ  . TYR B 2 274 ? 134.360 107.927 157.601 1.00 92.19  ? 264 TYR B CZ  1 
ATOM 4034 O OH  . TYR B 2 274 ? 133.943 106.781 158.234 1.00 92.01  ? 264 TYR B OH  1 
ATOM 4035 N N   . SER B 2 275 ? 137.217 114.534 155.525 1.00 89.78  ? 265 SER B N   1 
ATOM 4036 C CA  . SER B 2 275 ? 137.168 115.888 155.004 1.00 92.75  ? 265 SER B CA  1 
ATOM 4037 C C   . SER B 2 275 ? 138.339 116.125 154.067 1.00 98.32  ? 265 SER B C   1 
ATOM 4038 O O   . SER B 2 275 ? 139.415 115.542 154.228 1.00 103.52 ? 265 SER B O   1 
ATOM 4039 C CB  . SER B 2 275 ? 137.190 116.920 156.136 1.00 98.13  ? 265 SER B CB  1 
ATOM 4040 O OG  . SER B 2 275 ? 138.370 116.793 156.909 1.00 102.26 ? 265 SER B OG  1 
ATOM 4041 N N   . HIS B 2 276 ? 138.112 116.988 153.084 1.00 97.88  ? 266 HIS B N   1 
ATOM 4042 C CA  . HIS B 2 276 ? 139.161 117.483 152.210 1.00 103.14 ? 266 HIS B CA  1 
ATOM 4043 C C   . HIS B 2 276 ? 138.981 118.983 152.049 1.00 105.72 ? 266 HIS B C   1 
ATOM 4044 O O   . HIS B 2 276 ? 137.873 119.506 152.191 1.00 105.26 ? 266 HIS B O   1 
ATOM 4045 C CB  . HIS B 2 276 ? 139.141 116.795 150.841 1.00 109.72 ? 266 HIS B CB  1 
ATOM 4046 C CG  . HIS B 2 276 ? 140.013 115.582 150.759 1.00 121.12 ? 266 HIS B CG  1 
ATOM 4047 N ND1 . HIS B 2 276 ? 139.891 114.517 151.626 1.00 123.91 ? 266 HIS B ND1 1 
ATOM 4048 C CD2 . HIS B 2 276 ? 141.019 115.264 149.911 1.00 122.12 ? 266 HIS B CD2 1 
ATOM 4049 C CE1 . HIS B 2 276 ? 140.786 113.596 151.317 1.00 122.89 ? 266 HIS B CE1 1 
ATOM 4050 N NE2 . HIS B 2 276 ? 141.483 114.024 150.280 1.00 125.39 ? 266 HIS B NE2 1 
ATOM 4051 N N   . ASP B 2 277 ? 140.087 119.674 151.768 1.00 110.31 ? 267 ASP B N   1 
ATOM 4052 C CA  . ASP B 2 277 ? 140.019 121.118 151.578 1.00 112.85 ? 267 ASP B CA  1 
ATOM 4053 C C   . ASP B 2 277 ? 139.273 121.472 150.298 1.00 108.72 ? 267 ASP B C   1 
ATOM 4054 O O   . ASP B 2 277 ? 138.538 122.464 150.255 1.00 107.92 ? 267 ASP B O   1 
ATOM 4055 C CB  . ASP B 2 277 ? 141.428 121.711 151.561 1.00 117.56 ? 267 ASP B CB  1 
ATOM 4056 C CG  . ASP B 2 277 ? 142.266 121.254 152.740 1.00 120.91 ? 267 ASP B CG  1 
ATOM 4057 O OD1 . ASP B 2 277 ? 141.686 120.973 153.811 1.00 121.50 ? 267 ASP B OD1 1 
ATOM 4058 O OD2 . ASP B 2 277 ? 143.504 121.176 152.597 1.00 118.55 ? 267 ASP B OD2 1 
ATOM 4059 N N   . ASN B 2 278 ? 139.444 120.669 149.248 1.00 108.69 ? 268 ASN B N   1 
ATOM 4060 C CA  . ASN B 2 278 ? 138.762 120.923 147.988 1.00 109.09 ? 268 ASN B CA  1 
ATOM 4061 C C   . ASN B 2 278 ? 137.291 120.546 148.035 1.00 105.24 ? 268 ASN B C   1 
ATOM 4062 O O   . ASN B 2 278 ? 136.524 120.992 147.175 1.00 106.04 ? 268 ASN B O   1 
ATOM 4063 C CB  . ASN B 2 278 ? 139.449 120.160 146.853 1.00 114.78 ? 268 ASN B CB  1 
ATOM 4064 C CG  . ASN B 2 278 ? 139.743 118.719 147.216 1.00 119.53 ? 268 ASN B CG  1 
ATOM 4065 O OD1 . ASN B 2 278 ? 140.385 118.441 148.228 1.00 119.86 ? 268 ASN B OD1 1 
ATOM 4066 N ND2 . ASN B 2 278 ? 139.273 117.793 146.389 1.00 119.19 ? 268 ASN B ND2 1 
ATOM 4067 N N   . ILE B 2 279 ? 136.886 119.733 149.008 1.00 104.20 ? 269 ILE B N   1 
ATOM 4068 C CA  . ILE B 2 279 ? 135.485 119.360 149.154 1.00 99.24  ? 269 ILE B CA  1 
ATOM 4069 C C   . ILE B 2 279 ? 134.714 120.577 149.649 1.00 97.47  ? 269 ILE B C   1 
ATOM 4070 O O   . ILE B 2 279 ? 135.019 121.138 150.707 1.00 102.17 ? 269 ILE B O   1 
ATOM 4071 C CB  . ILE B 2 279 ? 135.339 118.165 150.104 1.00 94.20  ? 269 ILE B CB  1 
ATOM 4072 C CG1 . ILE B 2 279 ? 135.735 116.873 149.391 1.00 93.57  ? 269 ILE B CG1 1 
ATOM 4073 C CG2 . ILE B 2 279 ? 133.934 118.054 150.612 1.00 92.86  ? 269 ILE B CG2 1 
ATOM 4074 C CD1 . ILE B 2 279 ? 134.840 116.516 148.233 1.00 89.63  ? 269 ILE B CD1 1 
ATOM 4075 N N   . ILE B 2 280 ? 133.722 121.002 148.872 1.00 92.98  ? 270 ILE B N   1 
ATOM 4076 C CA  . ILE B 2 280 ? 133.112 122.309 149.067 1.00 94.43  ? 270 ILE B CA  1 
ATOM 4077 C C   . ILE B 2 280 ? 131.595 122.179 149.084 1.00 95.13  ? 270 ILE B C   1 
ATOM 4078 O O   . ILE B 2 280 ? 130.880 123.131 149.407 1.00 95.57  ? 270 ILE B O   1 
ATOM 4079 C CB  . ILE B 2 280 ? 133.589 123.286 147.972 1.00 99.65  ? 270 ILE B CB  1 
ATOM 4080 C CG1 . ILE B 2 280 ? 133.603 124.727 148.484 1.00 96.33  ? 270 ILE B CG1 1 
ATOM 4081 C CG2 . ILE B 2 280 ? 132.748 123.150 146.703 1.00 103.02 ? 270 ILE B CG2 1 
ATOM 4082 C CD1 . ILE B 2 280 ? 134.297 125.699 147.554 1.00 92.70  ? 270 ILE B CD1 1 
ATOM 4083 N N   . CYS B 2 281 ? 131.089 120.999 148.759 1.00 96.00  ? 271 CYS B N   1 
ATOM 4084 C CA  . CYS B 2 281 ? 129.658 120.785 148.630 1.00 93.77  ? 271 CYS B CA  1 
ATOM 4085 C C   . CYS B 2 281 ? 129.221 119.641 149.534 1.00 94.54  ? 271 CYS B C   1 
ATOM 4086 O O   . CYS B 2 281 ? 129.993 118.720 149.815 1.00 100.14 ? 271 CYS B O   1 
ATOM 4087 C CB  . CYS B 2 281 ? 129.283 120.496 147.178 1.00 96.83  ? 271 CYS B CB  1 
ATOM 4088 S SG  . CYS B 2 281 ? 129.247 121.954 146.108 1.00 119.75 ? 271 CYS B SG  1 
ATOM 4089 N N   . GLY B 2 282 ? 127.967 119.704 149.975 1.00 92.02  ? 272 GLY B N   1 
ATOM 4090 C CA  . GLY B 2 282 ? 127.473 118.828 151.020 1.00 89.43  ? 272 GLY B CA  1 
ATOM 4091 C C   . GLY B 2 282 ? 127.234 117.376 150.656 1.00 86.48  ? 272 GLY B C   1 
ATOM 4092 O O   . GLY B 2 282 ? 127.721 116.879 149.637 1.00 93.70  ? 272 GLY B O   1 
ATOM 4093 N N   . ILE B 2 283 ? 126.475 116.687 151.504 1.00 77.22  ? 273 ILE B N   1 
ATOM 4094 C CA  . ILE B 2 283 ? 126.227 115.257 151.392 1.00 73.94  ? 273 ILE B CA  1 
ATOM 4095 C C   . ILE B 2 283 ? 124.731 115.058 151.223 1.00 78.30  ? 273 ILE B C   1 
ATOM 4096 O O   . ILE B 2 283 ? 123.939 115.651 151.962 1.00 88.49  ? 273 ILE B O   1 
ATOM 4097 C CB  . ILE B 2 283 ? 126.733 114.500 152.632 1.00 80.55  ? 273 ILE B CB  1 
ATOM 4098 C CG1 . ILE B 2 283 ? 128.252 114.467 152.650 1.00 83.56  ? 273 ILE B CG1 1 
ATOM 4099 C CG2 . ILE B 2 283 ? 126.234 113.068 152.629 1.00 79.61  ? 273 ILE B CG2 1 
ATOM 4100 C CD1 . ILE B 2 283 ? 128.825 113.889 151.415 1.00 85.16  ? 273 ILE B CD1 1 
ATOM 4101 N N   . THR B 2 284 ? 124.344 114.246 150.246 1.00 78.43  ? 274 THR B N   1 
ATOM 4102 C CA  . THR B 2 284 ? 122.942 113.931 150.015 1.00 79.30  ? 274 THR B CA  1 
ATOM 4103 C C   . THR B 2 284 ? 122.557 112.524 150.439 1.00 81.06  ? 274 THR B C   1 
ATOM 4104 O O   . THR B 2 284 ? 121.477 112.331 150.999 1.00 86.28  ? 274 THR B O   1 
ATOM 4105 C CB  . THR B 2 284 ? 122.605 114.117 148.539 1.00 81.47  ? 274 THR B CB  1 
ATOM 4106 O OG1 . THR B 2 284 ? 123.529 113.368 147.742 1.00 85.51  ? 274 THR B OG1 1 
ATOM 4107 C CG2 . THR B 2 284 ? 122.736 115.571 148.171 1.00 85.47  ? 274 THR B CG2 1 
ATOM 4108 N N   . SER B 2 285 ? 123.407 111.534 150.186 1.00 76.57  ? 275 SER B N   1 
ATOM 4109 C CA  . SER B 2 285 ? 123.097 110.151 150.509 1.00 70.94  ? 275 SER B CA  1 
ATOM 4110 C C   . SER B 2 285 ? 124.353 109.437 150.982 1.00 71.16  ? 275 SER B C   1 
ATOM 4111 O O   . SER B 2 285 ? 125.458 109.729 150.524 1.00 80.47  ? 275 SER B O   1 
ATOM 4112 C CB  . SER B 2 285 ? 122.498 109.433 149.303 1.00 79.35  ? 275 SER B CB  1 
ATOM 4113 O OG  . SER B 2 285 ? 123.464 109.306 148.278 1.00 82.64  ? 275 SER B OG  1 
ATOM 4114 N N   . VAL B 2 286 ? 124.171 108.498 151.907 1.00 70.83  ? 276 VAL B N   1 
ATOM 4115 C CA  . VAL B 2 286 ? 125.269 107.722 152.476 1.00 75.04  ? 276 VAL B CA  1 
ATOM 4116 C C   . VAL B 2 286 ? 124.824 106.270 152.597 1.00 74.28  ? 276 VAL B C   1 
ATOM 4117 O O   . VAL B 2 286 ? 123.738 105.990 153.115 1.00 81.39  ? 276 VAL B O   1 
ATOM 4118 C CB  . VAL B 2 286 ? 125.707 108.286 153.845 1.00 82.02  ? 276 VAL B CB  1 
ATOM 4119 C CG1 . VAL B 2 286 ? 126.366 107.222 154.715 1.00 83.94  ? 276 VAL B CG1 1 
ATOM 4120 C CG2 . VAL B 2 286 ? 126.652 109.456 153.655 1.00 83.19  ? 276 VAL B CG2 1 
ATOM 4121 N N   . SER B 2 287 ? 125.655 105.349 152.109 1.00 69.56  ? 277 SER B N   1 
ATOM 4122 C CA  . SER B 2 287 ? 125.411 103.922 152.262 1.00 74.70  ? 277 SER B CA  1 
ATOM 4123 C C   . SER B 2 287 ? 126.746 103.206 152.392 1.00 74.16  ? 277 SER B C   1 
ATOM 4124 O O   . SER B 2 287 ? 127.790 103.723 151.989 1.00 82.72  ? 277 SER B O   1 
ATOM 4125 C CB  . SER B 2 287 ? 124.608 103.352 151.087 1.00 86.28  ? 277 SER B CB  1 
ATOM 4126 O OG  . SER B 2 287 ? 123.416 104.086 150.869 1.00 88.57  ? 277 SER B OG  1 
ATOM 4127 N N   . PHE B 2 288 ? 126.704 102.006 152.961 1.00 69.90  ? 278 PHE B N   1 
ATOM 4128 C CA  . PHE B 2 288 ? 127.892 101.204 153.213 1.00 70.94  ? 278 PHE B CA  1 
ATOM 4129 C C   . PHE B 2 288 ? 127.949 100.007 152.271 1.00 74.03  ? 278 PHE B C   1 
ATOM 4130 O O   . PHE B 2 288 ? 127.130 99.862  151.362 1.00 80.75  ? 278 PHE B O   1 
ATOM 4131 C CB  . PHE B 2 288 ? 127.947 100.738 154.669 1.00 75.04  ? 278 PHE B CB  1 
ATOM 4132 C CG  . PHE B 2 288 ? 128.375 101.796 155.639 1.00 76.87  ? 278 PHE B CG  1 
ATOM 4133 C CD1 . PHE B 2 288 ? 127.657 102.964 155.798 1.00 81.11  ? 278 PHE B CD1 1 
ATOM 4134 C CD2 . PHE B 2 288 ? 129.522 101.621 156.381 1.00 79.86  ? 278 PHE B CD2 1 
ATOM 4135 C CE1 . PHE B 2 288 ? 128.067 103.922 156.687 1.00 88.33  ? 278 PHE B CE1 1 
ATOM 4136 C CE2 . PHE B 2 288 ? 129.939 102.580 157.262 1.00 88.32  ? 278 PHE B CE2 1 
ATOM 4137 C CZ  . PHE B 2 288 ? 129.212 103.724 157.421 1.00 92.77  ? 278 PHE B CZ  1 
ATOM 4138 N N   . SER B 2 289 ? 128.932 99.146  152.496 1.00 75.76  ? 279 SER B N   1 
ATOM 4139 C CA  . SER B 2 289 ? 129.095 97.891  151.783 1.00 75.32  ? 279 SER B CA  1 
ATOM 4140 C C   . SER B 2 289 ? 128.764 96.732  152.715 1.00 78.35  ? 279 SER B C   1 
ATOM 4141 O O   . SER B 2 289 ? 128.333 96.924  153.855 1.00 85.45  ? 279 SER B O   1 
ATOM 4142 C CB  . SER B 2 289 ? 130.514 97.762  151.232 1.00 74.30  ? 279 SER B CB  1 
ATOM 4143 O OG  . SER B 2 289 ? 130.690 96.519  150.580 1.00 72.86  ? 279 SER B OG  1 
ATOM 4144 N N   . LYS B 2 290 ? 128.958 95.513  152.210 1.00 79.78  ? 280 LYS B N   1 
ATOM 4145 C CA  . LYS B 2 290 ? 128.636 94.329  153.001 1.00 86.94  ? 280 LYS B CA  1 
ATOM 4146 C C   . LYS B 2 290 ? 129.618 94.149  154.150 1.00 85.40  ? 280 LYS B C   1 
ATOM 4147 O O   . LYS B 2 290 ? 129.221 93.789  155.264 1.00 90.44  ? 280 LYS B O   1 
ATOM 4148 C CB  . LYS B 2 290 ? 128.617 93.091  152.107 1.00 92.58  ? 280 LYS B CB  1 
ATOM 4149 C CG  . LYS B 2 290 ? 128.178 91.817  152.811 1.00 96.12  ? 280 LYS B CG  1 
ATOM 4150 C CD  . LYS B 2 290 ? 126.697 91.853  153.148 1.00 98.46  ? 280 LYS B CD  1 
ATOM 4151 C CE  . LYS B 2 290 ? 126.238 90.534  153.748 1.00 102.56 ? 280 LYS B CE  1 
ATOM 4152 N NZ  . LYS B 2 290 ? 126.314 89.422  152.760 1.00 100.89 ? 280 LYS B NZ  1 
ATOM 4153 N N   . SER B 2 291 ? 130.901 94.399  153.904 1.00 80.96  ? 281 SER B N   1 
ATOM 4154 C CA  . SER B 2 291 ? 131.892 94.304  154.964 1.00 89.72  ? 281 SER B CA  1 
ATOM 4155 C C   . SER B 2 291 ? 131.887 95.520  155.872 1.00 92.78  ? 281 SER B C   1 
ATOM 4156 O O   . SER B 2 291 ? 132.455 95.463  156.967 1.00 91.20  ? 281 SER B O   1 
ATOM 4157 C CB  . SER B 2 291 ? 133.287 94.124  154.368 1.00 89.92  ? 281 SER B CB  1 
ATOM 4158 O OG  . SER B 2 291 ? 133.605 95.194  153.495 1.00 89.24  ? 281 SER B OG  1 
ATOM 4159 N N   . GLY B 2 292 ? 131.270 96.615  155.443 1.00 93.52  ? 282 GLY B N   1 
ATOM 4160 C CA  . GLY B 2 292 ? 131.319 97.853  156.182 1.00 95.99  ? 282 GLY B CA  1 
ATOM 4161 C C   . GLY B 2 292 ? 132.595 98.637  155.996 1.00 98.41  ? 282 GLY B C   1 
ATOM 4162 O O   . GLY B 2 292 ? 132.719 99.732  156.558 1.00 102.62 ? 282 GLY B O   1 
ATOM 4163 N N   . ARG B 2 293 ? 133.544 98.116  155.221 1.00 90.87  ? 283 ARG B N   1 
ATOM 4164 C CA  . ARG B 2 293 ? 134.805 98.810  155.012 1.00 83.82  ? 283 ARG B CA  1 
ATOM 4165 C C   . ARG B 2 293 ? 134.635 100.001 154.081 1.00 78.96  ? 283 ARG B C   1 
ATOM 4166 O O   . ARG B 2 293 ? 135.142 101.086 154.364 1.00 83.51  ? 283 ARG B O   1 
ATOM 4167 C CB  . ARG B 2 293 ? 135.842 97.837  154.457 1.00 89.54  ? 283 ARG B CB  1 
ATOM 4168 C CG  . ARG B 2 293 ? 137.078 98.490  153.875 1.00 93.68  ? 283 ARG B CG  1 
ATOM 4169 C CD  . ARG B 2 293 ? 137.974 99.047  154.960 1.00 92.40  ? 283 ARG B CD  1 
ATOM 4170 N NE  . ARG B 2 293 ? 139.263 99.464  154.423 1.00 96.51  ? 283 ARG B NE  1 
ATOM 4171 C CZ  . ARG B 2 293 ? 140.425 98.938  154.782 1.00 94.44  ? 283 ARG B CZ  1 
ATOM 4172 N NH1 . ARG B 2 293 ? 140.495 97.961  155.669 1.00 89.50  ? 283 ARG B NH1 1 
ATOM 4173 N NH2 . ARG B 2 293 ? 141.543 99.399  154.230 1.00 98.38  ? 283 ARG B NH2 1 
ATOM 4174 N N   . LEU B 2 294 ? 133.895 99.845  153.000 1.00 76.20  ? 284 LEU B N   1 
ATOM 4175 C CA  . LEU B 2 294 ? 133.823 100.871 151.969 1.00 75.94  ? 284 LEU B CA  1 
ATOM 4176 C C   . LEU B 2 294 ? 132.465 101.555 152.077 1.00 82.39  ? 284 LEU B C   1 
ATOM 4177 O O   . LEU B 2 294 ? 131.444 100.979 151.693 1.00 91.40  ? 284 LEU B O   1 
ATOM 4178 C CB  . LEU B 2 294 ? 134.024 100.253 150.591 1.00 78.79  ? 284 LEU B CB  1 
ATOM 4179 C CG  . LEU B 2 294 ? 135.452 100.188 150.048 1.00 84.00  ? 284 LEU B CG  1 
ATOM 4180 C CD1 . LEU B 2 294 ? 135.459 99.761  148.586 1.00 81.99  ? 284 LEU B CD1 1 
ATOM 4181 C CD2 . LEU B 2 294 ? 136.216 101.484 150.256 1.00 87.90  ? 284 LEU B CD2 1 
ATOM 4182 N N   . LEU B 2 295 ? 132.444 102.779 152.598 1.00 78.12  ? 285 LEU B N   1 
ATOM 4183 C CA  . LEU B 2 295 ? 131.213 103.553 152.622 1.00 78.73  ? 285 LEU B CA  1 
ATOM 4184 C C   . LEU B 2 295 ? 131.215 104.541 151.466 1.00 75.86  ? 285 LEU B C   1 
ATOM 4185 O O   . LEU B 2 295 ? 132.256 105.074 151.077 1.00 85.73  ? 285 LEU B O   1 
ATOM 4186 C CB  . LEU B 2 295 ? 131.013 104.291 153.953 1.00 77.28  ? 285 LEU B CB  1 
ATOM 4187 C CG  . LEU B 2 295 ? 131.619 105.643 154.341 1.00 81.19  ? 285 LEU B CG  1 
ATOM 4188 C CD1 . LEU B 2 295 ? 130.723 106.813 153.952 1.00 83.12  ? 285 LEU B CD1 1 
ATOM 4189 C CD2 . LEU B 2 295 ? 131.859 105.676 155.829 1.00 84.74  ? 285 LEU B CD2 1 
ATOM 4190 N N   . LEU B 2 296 ? 130.031 104.779 150.919 1.00 69.15  ? 286 LEU B N   1 
ATOM 4191 C CA  . LEU B 2 296 ? 129.860 105.626 149.753 1.00 69.74  ? 286 LEU B CA  1 
ATOM 4192 C C   . LEU B 2 296 ? 128.987 106.812 150.117 1.00 74.91  ? 286 LEU B C   1 
ATOM 4193 O O   . LEU B 2 296 ? 127.934 106.653 150.739 1.00 82.81  ? 286 LEU B O   1 
ATOM 4194 C CB  . LEU B 2 296 ? 129.238 104.848 148.600 1.00 74.24  ? 286 LEU B CB  1 
ATOM 4195 C CG  . LEU B 2 296 ? 129.723 103.408 148.451 1.00 79.68  ? 286 LEU B CG  1 
ATOM 4196 C CD1 . LEU B 2 296 ? 128.867 102.678 147.449 1.00 81.46  ? 286 LEU B CD1 1 
ATOM 4197 C CD2 . LEU B 2 296 ? 131.181 103.365 148.037 1.00 78.55  ? 286 LEU B CD2 1 
ATOM 4198 N N   . ALA B 2 297 ? 129.432 108.000 149.729 1.00 75.67  ? 287 ALA B N   1 
ATOM 4199 C CA  . ALA B 2 297 ? 128.742 109.242 150.049 1.00 79.88  ? 287 ALA B CA  1 
ATOM 4200 C C   . ALA B 2 297 ? 128.298 109.901 148.753 1.00 78.86  ? 287 ALA B C   1 
ATOM 4201 O O   . ALA B 2 297 ? 129.132 110.384 147.980 1.00 85.95  ? 287 ALA B O   1 
ATOM 4202 C CB  . ALA B 2 297 ? 129.640 110.175 150.859 1.00 82.74  ? 287 ALA B CB  1 
ATOM 4203 N N   . GLY B 2 298 ? 126.991 109.911 148.515 1.00 78.89  ? 288 GLY B N   1 
ATOM 4204 C CA  . GLY B 2 298 ? 126.431 110.670 147.418 1.00 79.45  ? 288 GLY B CA  1 
ATOM 4205 C C   . GLY B 2 298 ? 126.601 112.148 147.677 1.00 81.92  ? 288 GLY B C   1 
ATOM 4206 O O   . GLY B 2 298 ? 125.972 112.704 148.582 1.00 89.76  ? 288 GLY B O   1 
ATOM 4207 N N   . TYR B 2 299 ? 127.453 112.797 146.900 1.00 79.40  ? 289 TYR B N   1 
ATOM 4208 C CA  . TYR B 2 299 ? 127.858 114.151 147.224 1.00 75.85  ? 289 TYR B CA  1 
ATOM 4209 C C   . TYR B 2 299 ? 126.906 115.152 146.580 1.00 81.21  ? 289 TYR B C   1 
ATOM 4210 O O   . TYR B 2 299 ? 125.870 114.797 146.014 1.00 80.86  ? 289 TYR B O   1 
ATOM 4211 C CB  . TYR B 2 299 ? 129.287 114.409 146.774 1.00 77.39  ? 289 TYR B CB  1 
ATOM 4212 C CG  . TYR B 2 299 ? 130.267 114.483 147.906 1.00 79.68  ? 289 TYR B CG  1 
ATOM 4213 C CD1 . TYR B 2 299 ? 130.800 113.327 148.456 1.00 81.67  ? 289 TYR B CD1 1 
ATOM 4214 C CD2 . TYR B 2 299 ? 130.625 115.696 148.456 1.00 83.72  ? 289 TYR B CD2 1 
ATOM 4215 C CE1 . TYR B 2 299 ? 131.702 113.380 149.494 1.00 84.40  ? 289 TYR B CE1 1 
ATOM 4216 C CE2 . TYR B 2 299 ? 131.511 115.762 149.500 1.00 89.29  ? 289 TYR B CE2 1 
ATOM 4217 C CZ  . TYR B 2 299 ? 132.048 114.603 150.019 1.00 90.86  ? 289 TYR B CZ  1 
ATOM 4218 O OH  . TYR B 2 299 ? 132.938 114.674 151.065 1.00 93.89  ? 289 TYR B OH  1 
ATOM 4219 N N   . ASP B 2 300 ? 127.271 116.428 146.657 1.00 89.13  ? 290 ASP B N   1 
ATOM 4220 C CA  . ASP B 2 300 ? 126.470 117.517 146.127 1.00 95.03  ? 290 ASP B CA  1 
ATOM 4221 C C   . ASP B 2 300 ? 127.085 118.178 144.905 1.00 93.81  ? 290 ASP B C   1 
ATOM 4222 O O   . ASP B 2 300 ? 126.367 118.853 144.164 1.00 96.14  ? 290 ASP B O   1 
ATOM 4223 C CB  . ASP B 2 300 ? 126.250 118.577 147.218 1.00 100.10 ? 290 ASP B CB  1 
ATOM 4224 C CG  . ASP B 2 300 ? 124.992 119.375 147.012 1.00 103.92 ? 290 ASP B CG  1 
ATOM 4225 O OD1 . ASP B 2 300 ? 124.115 118.884 146.283 1.00 102.91 ? 290 ASP B OD1 1 
ATOM 4226 O OD2 . ASP B 2 300 ? 124.870 120.478 147.583 1.00 106.98 ? 290 ASP B OD2 1 
ATOM 4227 N N   . ASP B 2 301 ? 128.382 118.001 144.680 1.00 92.10  ? 291 ASP B N   1 
ATOM 4228 C CA  . ASP B 2 301 ? 129.101 118.597 143.551 1.00 93.74  ? 291 ASP B CA  1 
ATOM 4229 C C   . ASP B 2 301 ? 129.102 117.689 142.314 1.00 91.50  ? 291 ASP B C   1 
ATOM 4230 O O   . ASP B 2 301 ? 130.113 117.335 141.696 1.00 97.69  ? 291 ASP B O   1 
ATOM 4231 C CB  . ASP B 2 301 ? 130.495 119.062 144.022 1.00 99.79  ? 291 ASP B CB  1 
ATOM 4232 C CG  . ASP B 2 301 ? 131.556 117.958 144.094 1.00 106.86 ? 291 ASP B CG  1 
ATOM 4233 O OD1 . ASP B 2 301 ? 132.758 118.298 144.043 1.00 119.11 ? 291 ASP B OD1 1 
ATOM 4234 O OD2 . ASP B 2 301 ? 131.206 116.774 144.274 1.00 102.38 ? 291 ASP B OD2 1 
ATOM 4235 N N   . PHE B 2 302 ? 127.869 117.327 141.949 1.00 82.87  ? 292 PHE B N   1 
ATOM 4236 C CA  . PHE B 2 302 ? 127.483 116.737 140.668 1.00 80.76  ? 292 PHE B CA  1 
ATOM 4237 C C   . PHE B 2 302 ? 128.025 115.317 140.498 1.00 90.58  ? 292 PHE B C   1 
ATOM 4238 O O   . PHE B 2 302 ? 128.008 114.773 139.390 1.00 94.53  ? 292 PHE B O   1 
ATOM 4239 C CB  . PHE B 2 302 ? 127.952 117.611 139.494 1.00 89.40  ? 292 PHE B CB  1 
ATOM 4240 C CG  . PHE B 2 302 ? 127.052 118.770 139.194 1.00 100.99 ? 292 PHE B CG  1 
ATOM 4241 C CD1 . PHE B 2 302 ? 125.689 118.615 139.101 1.00 97.06  ? 292 PHE B CD1 1 
ATOM 4242 C CD2 . PHE B 2 302 ? 127.590 120.029 138.978 1.00 113.30 ? 292 PHE B CD2 1 
ATOM 4243 C CE1 . PHE B 2 302 ? 124.868 119.697 138.816 1.00 102.56 ? 292 PHE B CE1 1 
ATOM 4244 C CE2 . PHE B 2 302 ? 126.777 121.116 138.689 1.00 116.09 ? 292 PHE B CE2 1 
ATOM 4245 C CZ  . PHE B 2 302 ? 125.412 120.947 138.607 1.00 112.15 ? 292 PHE B CZ  1 
ATOM 4246 N N   . ASN B 2 303 ? 128.508 114.705 141.577 1.00 97.05  ? 293 ASN B N   1 
ATOM 4247 C CA  . ASN B 2 303 ? 129.127 113.387 141.535 1.00 89.70  ? 293 ASN B CA  1 
ATOM 4248 C C   . ASN B 2 303 ? 129.065 112.773 142.929 1.00 87.14  ? 293 ASN B C   1 
ATOM 4249 O O   . ASN B 2 303 ? 128.391 113.290 143.824 1.00 92.43  ? 293 ASN B O   1 
ATOM 4250 C CB  . ASN B 2 303 ? 130.561 113.474 141.008 1.00 82.55  ? 293 ASN B CB  1 
ATOM 4251 C CG  . ASN B 2 303 ? 131.519 114.049 142.020 1.00 86.92  ? 293 ASN B CG  1 
ATOM 4252 O OD1 . ASN B 2 303 ? 132.182 113.320 142.752 1.00 86.24  ? 293 ASN B OD1 1 
ATOM 4253 N ND2 . ASN B 2 303 ? 131.597 115.373 142.068 1.00 92.89  ? 293 ASN B ND2 1 
ATOM 4254 N N   . CYS B 2 304 ? 129.762 111.651 143.110 1.00 79.41  ? 294 CYS B N   1 
ATOM 4255 C CA  . CYS B 2 304 ? 129.731 110.934 144.377 1.00 78.22  ? 294 CYS B CA  1 
ATOM 4256 C C   . CYS B 2 304 ? 131.052 110.208 144.594 1.00 77.28  ? 294 CYS B C   1 
ATOM 4257 O O   . CYS B 2 304 ? 131.808 109.960 143.652 1.00 83.91  ? 294 CYS B O   1 
ATOM 4258 C CB  . CYS B 2 304 ? 128.539 109.973 144.432 1.00 83.46  ? 294 CYS B CB  1 
ATOM 4259 S SG  . CYS B 2 304 ? 128.847 108.329 143.817 1.00 100.22 ? 294 CYS B SG  1 
ATOM 4260 N N   . ASN B 2 305 ? 131.325 109.876 145.856 1.00 75.11  ? 295 ASN B N   1 
ATOM 4261 C CA  . ASN B 2 305 ? 132.668 109.534 146.308 1.00 76.09  ? 295 ASN B CA  1 
ATOM 4262 C C   . ASN B 2 305 ? 132.671 108.233 147.101 1.00 77.39  ? 295 ASN B C   1 
ATOM 4263 O O   . ASN B 2 305 ? 131.623 107.707 147.484 1.00 87.25  ? 295 ASN B O   1 
ATOM 4264 C CB  . ASN B 2 305 ? 133.253 110.654 147.174 1.00 81.88  ? 295 ASN B CB  1 
ATOM 4265 C CG  . ASN B 2 305 ? 133.895 111.751 146.355 1.00 93.94  ? 295 ASN B CG  1 
ATOM 4266 O OD1 . ASN B 2 305 ? 133.353 112.179 145.338 1.00 97.12  ? 295 ASN B OD1 1 
ATOM 4267 N ND2 . ASN B 2 305 ? 135.045 112.227 146.804 1.00 95.53  ? 295 ASN B ND2 1 
ATOM 4268 N N   . VAL B 2 306 ? 133.877 107.718 147.341 1.00 73.06  ? 296 VAL B N   1 
ATOM 4269 C CA  . VAL B 2 306 ? 134.108 106.505 148.119 1.00 71.96  ? 296 VAL B CA  1 
ATOM 4270 C C   . VAL B 2 306 ? 135.047 106.849 149.267 1.00 75.56  ? 296 VAL B C   1 
ATOM 4271 O O   . VAL B 2 306 ? 136.053 107.537 149.063 1.00 85.96  ? 296 VAL B O   1 
ATOM 4272 C CB  . VAL B 2 306 ? 134.711 105.379 147.257 1.00 76.21  ? 296 VAL B CB  1 
ATOM 4273 C CG1 . VAL B 2 306 ? 134.888 104.115 148.063 1.00 74.23  ? 296 VAL B CG1 1 
ATOM 4274 C CG2 . VAL B 2 306 ? 133.852 105.096 146.063 1.00 76.51  ? 296 VAL B CG2 1 
ATOM 4275 N N   . TRP B 2 307 ? 134.725 106.372 150.466 1.00 73.43  ? 297 TRP B N   1 
ATOM 4276 C CA  . TRP B 2 307 ? 135.566 106.559 151.637 1.00 76.74  ? 297 TRP B CA  1 
ATOM 4277 C C   . TRP B 2 307 ? 135.929 105.208 152.239 1.00 79.91  ? 297 TRP B C   1 
ATOM 4278 O O   . TRP B 2 307 ? 135.289 104.191 151.963 1.00 87.99  ? 297 TRP B O   1 
ATOM 4279 C CB  . TRP B 2 307 ? 134.865 107.437 152.671 1.00 80.57  ? 297 TRP B CB  1 
ATOM 4280 C CG  . TRP B 2 307 ? 134.784 108.854 152.237 1.00 85.32  ? 297 TRP B CG  1 
ATOM 4281 C CD1 . TRP B 2 307 ? 133.715 109.474 151.669 1.00 90.29  ? 297 TRP B CD1 1 
ATOM 4282 C CD2 . TRP B 2 307 ? 135.821 109.833 152.318 1.00 81.84  ? 297 TRP B CD2 1 
ATOM 4283 N NE1 . TRP B 2 307 ? 134.019 110.782 151.396 1.00 92.62  ? 297 TRP B NE1 1 
ATOM 4284 C CE2 . TRP B 2 307 ? 135.308 111.027 151.786 1.00 82.83  ? 297 TRP B CE2 1 
ATOM 4285 C CE3 . TRP B 2 307 ? 137.133 109.815 152.793 1.00 85.38  ? 297 TRP B CE3 1 
ATOM 4286 C CZ2 . TRP B 2 307 ? 136.060 112.192 151.716 1.00 85.71  ? 297 TRP B CZ2 1 
ATOM 4287 C CZ3 . TRP B 2 307 ? 137.876 110.970 152.723 1.00 88.81  ? 297 TRP B CZ3 1 
ATOM 4288 C CH2 . TRP B 2 307 ? 137.340 112.143 152.189 1.00 89.89  ? 297 TRP B CH2 1 
ATOM 4289 N N   . ASP B 2 308 ? 136.965 105.206 153.079 1.00 79.79  ? 298 ASP B N   1 
ATOM 4290 C CA  . ASP B 2 308 ? 137.595 103.963 153.507 1.00 82.99  ? 298 ASP B CA  1 
ATOM 4291 C C   . ASP B 2 308 ? 137.167 103.586 154.928 1.00 86.68  ? 298 ASP B C   1 
ATOM 4292 O O   . ASP B 2 308 ? 137.310 102.429 155.336 1.00 90.55  ? 298 ASP B O   1 
ATOM 4293 C CB  . ASP B 2 308 ? 139.121 104.126 153.356 1.00 93.64  ? 298 ASP B CB  1 
ATOM 4294 C CG  . ASP B 2 308 ? 139.948 103.145 154.183 1.00 106.13 ? 298 ASP B CG  1 
ATOM 4295 O OD1 . ASP B 2 308 ? 139.686 101.925 154.138 1.00 111.88 ? 298 ASP B OD1 1 
ATOM 4296 O OD2 . ASP B 2 308 ? 140.868 103.594 154.886 1.00 105.26 ? 298 ASP B OD2 1 
ATOM 4297 N N   . ALA B 2 309 ? 136.633 104.537 155.694 1.00 85.48  ? 299 ALA B N   1 
ATOM 4298 C CA  . ALA B 2 309 ? 135.885 104.347 156.940 1.00 86.87  ? 299 ALA B CA  1 
ATOM 4299 C C   . ALA B 2 309 ? 136.699 103.771 158.092 1.00 89.42  ? 299 ALA B C   1 
ATOM 4300 O O   . ALA B 2 309 ? 136.158 103.627 159.193 1.00 95.53  ? 299 ALA B O   1 
ATOM 4301 C CB  . ALA B 2 309 ? 134.641 103.466 156.752 1.00 91.50  ? 299 ALA B CB  1 
ATOM 4302 N N   . LEU B 2 310 ? 137.967 103.432 157.889 1.00 90.09  ? 300 LEU B N   1 
ATOM 4303 C CA  . LEU B 2 310 ? 138.882 103.125 158.977 1.00 101.08 ? 300 LEU B CA  1 
ATOM 4304 C C   . LEU B 2 310 ? 139.935 104.209 159.134 1.00 108.78 ? 300 LEU B C   1 
ATOM 4305 O O   . LEU B 2 310 ? 140.100 104.761 160.226 1.00 115.12 ? 300 LEU B O   1 
ATOM 4306 C CB  . LEU B 2 310 ? 139.544 101.763 158.749 1.00 99.33  ? 300 LEU B CB  1 
ATOM 4307 C CG  . LEU B 2 310 ? 138.581 100.578 158.826 1.00 96.58  ? 300 LEU B CG  1 
ATOM 4308 C CD1 . LEU B 2 310 ? 139.315 99.271  158.586 1.00 95.46  ? 300 LEU B CD1 1 
ATOM 4309 C CD2 . LEU B 2 310 ? 137.863 100.554 160.166 1.00 95.21  ? 300 LEU B CD2 1 
ATOM 4310 N N   . LYS B 2 311 ? 140.637 104.545 158.059 1.00 100.73 ? 301 LYS B N   1 
ATOM 4311 C CA  . LYS B 2 311 ? 141.357 105.804 157.984 1.00 103.80 ? 301 LYS B CA  1 
ATOM 4312 C C   . LYS B 2 311 ? 140.693 106.684 156.931 1.00 98.56  ? 301 LYS B C   1 
ATOM 4313 O O   . LYS B 2 311 ? 140.143 106.196 155.941 1.00 94.85  ? 301 LYS B O   1 
ATOM 4314 C CB  . LYS B 2 311 ? 142.845 105.587 157.679 1.00 108.07 ? 301 LYS B CB  1 
ATOM 4315 C CG  . LYS B 2 311 ? 143.204 105.297 156.233 1.00 107.95 ? 301 LYS B CG  1 
ATOM 4316 C CD  . LYS B 2 311 ? 144.332 104.285 156.124 1.00 115.39 ? 301 LYS B CD  1 
ATOM 4317 C CE  . LYS B 2 311 ? 143.907 102.929 156.660 1.00 117.56 ? 301 LYS B CE  1 
ATOM 4318 N NZ  . LYS B 2 311 ? 145.008 101.930 156.594 1.00 112.08 ? 301 LYS B NZ  1 
ATOM 4319 N N   . ALA B 2 312 ? 140.706 107.992 157.178 1.00 100.15 ? 302 ALA B N   1 
ATOM 4320 C CA  . ALA B 2 312 ? 139.991 108.945 156.331 1.00 100.15 ? 302 ALA B CA  1 
ATOM 4321 C C   . ALA B 2 312 ? 140.810 109.198 155.070 1.00 102.72 ? 302 ALA B C   1 
ATOM 4322 O O   . ALA B 2 312 ? 141.570 110.164 154.959 1.00 104.70 ? 302 ALA B O   1 
ATOM 4323 C CB  . ALA B 2 312 ? 139.713 110.237 157.087 1.00 99.70  ? 302 ALA B CB  1 
ATOM 4324 N N   . ASP B 2 313 ? 140.648 108.306 154.100 1.00 95.79  ? 303 ASP B N   1 
ATOM 4325 C CA  . ASP B 2 313 ? 141.320 108.422 152.817 1.00 91.59  ? 303 ASP B CA  1 
ATOM 4326 C C   . ASP B 2 313 ? 140.321 108.189 151.697 1.00 83.42  ? 303 ASP B C   1 
ATOM 4327 O O   . ASP B 2 313 ? 139.519 107.253 151.754 1.00 87.17  ? 303 ASP B O   1 
ATOM 4328 C CB  . ASP B 2 313 ? 142.479 107.428 152.701 1.00 98.78  ? 303 ASP B CB  1 
ATOM 4329 C CG  . ASP B 2 313 ? 143.802 108.022 153.145 1.00 109.92 ? 303 ASP B CG  1 
ATOM 4330 O OD1 . ASP B 2 313 ? 144.476 108.662 152.312 1.00 116.70 ? 303 ASP B OD1 1 
ATOM 4331 O OD2 . ASP B 2 313 ? 144.167 107.851 154.327 1.00 111.08 ? 303 ASP B OD2 1 
ATOM 4332 N N   . ARG B 2 314 ? 140.375 109.043 150.681 1.00 82.88  ? 304 ARG B N   1 
ATOM 4333 C CA  . ARG B 2 314 ? 139.520 108.897 149.510 1.00 89.07  ? 304 ARG B CA  1 
ATOM 4334 C C   . ARG B 2 314 ? 140.060 107.762 148.655 1.00 94.24  ? 304 ARG B C   1 
ATOM 4335 O O   . ARG B 2 314 ? 141.133 107.882 148.054 1.00 98.40  ? 304 ARG B O   1 
ATOM 4336 C CB  . ARG B 2 314 ? 139.467 110.197 148.717 1.00 96.18  ? 304 ARG B CB  1 
ATOM 4337 C CG  . ARG B 2 314 ? 138.141 110.917 148.802 1.00 98.13  ? 304 ARG B CG  1 
ATOM 4338 C CD  . ARG B 2 314 ? 138.161 112.176 147.968 1.00 102.10 ? 304 ARG B CD  1 
ATOM 4339 N NE  . ARG B 2 314 ? 138.204 111.873 146.543 1.00 105.59 ? 304 ARG B NE  1 
ATOM 4340 C CZ  . ARG B 2 314 ? 138.013 112.766 145.582 1.00 109.05 ? 304 ARG B CZ  1 
ATOM 4341 N NH1 . ARG B 2 314 ? 137.760 114.035 145.858 1.00 112.49 ? 304 ARG B NH1 1 
ATOM 4342 N NH2 . ARG B 2 314 ? 138.076 112.376 144.312 1.00 103.03 ? 304 ARG B NH2 1 
ATOM 4343 N N   . ALA B 2 315 ? 139.323 106.660 148.599 1.00 89.09  ? 305 ALA B N   1 
ATOM 4344 C CA  . ALA B 2 315 ? 139.751 105.479 147.868 1.00 89.34  ? 305 ALA B CA  1 
ATOM 4345 C C   . ALA B 2 315 ? 139.185 105.402 146.458 1.00 89.70  ? 305 ALA B C   1 
ATOM 4346 O O   . ALA B 2 315 ? 139.515 104.462 145.729 1.00 95.01  ? 305 ALA B O   1 
ATOM 4347 C CB  . ALA B 2 315 ? 139.364 104.220 148.643 1.00 90.54  ? 305 ALA B CB  1 
ATOM 4348 N N   . GLY B 2 316 ? 138.349 106.348 146.052 1.00 87.19  ? 306 GLY B N   1 
ATOM 4349 C CA  . GLY B 2 316 ? 137.795 106.292 144.713 1.00 83.07  ? 306 GLY B CA  1 
ATOM 4350 C C   . GLY B 2 316 ? 136.790 107.397 144.494 1.00 80.67  ? 306 GLY B C   1 
ATOM 4351 O O   . GLY B 2 316 ? 136.485 108.183 145.396 1.00 85.62  ? 306 GLY B O   1 
ATOM 4352 N N   . VAL B 2 317 ? 136.277 107.444 143.268 1.00 73.87  ? 307 VAL B N   1 
ATOM 4353 C CA  . VAL B 2 317 ? 135.284 108.437 142.875 1.00 70.95  ? 307 VAL B CA  1 
ATOM 4354 C C   . VAL B 2 317 ? 134.492 107.873 141.702 1.00 72.07  ? 307 VAL B C   1 
ATOM 4355 O O   . VAL B 2 317 ? 135.041 107.184 140.838 1.00 78.43  ? 307 VAL B O   1 
ATOM 4356 C CB  . VAL B 2 317 ? 135.955 109.797 142.551 1.00 77.60  ? 307 VAL B CB  1 
ATOM 4357 C CG1 . VAL B 2 317 ? 136.976 109.670 141.422 1.00 77.54  ? 307 VAL B CG1 1 
ATOM 4358 C CG2 . VAL B 2 317 ? 134.920 110.873 142.240 1.00 77.59  ? 307 VAL B CG2 1 
ATOM 4359 N N   . LEU B 2 318 ? 133.186 108.122 141.708 1.00 72.14  ? 308 LEU B N   1 
ATOM 4360 C CA  . LEU B 2 318 ? 132.293 107.729 140.627 1.00 69.57  ? 308 LEU B CA  1 
ATOM 4361 C C   . LEU B 2 318 ? 131.629 108.976 140.068 1.00 73.22  ? 308 LEU B C   1 
ATOM 4362 O O   . LEU B 2 318 ? 130.940 109.695 140.798 1.00 79.25  ? 308 LEU B O   1 
ATOM 4363 C CB  . LEU B 2 318 ? 131.228 106.733 141.102 1.00 64.07  ? 308 LEU B CB  1 
ATOM 4364 C CG  . LEU B 2 318 ? 131.603 105.578 142.035 1.00 69.74  ? 308 LEU B CG  1 
ATOM 4365 C CD1 . LEU B 2 318 ? 131.458 105.945 143.489 1.00 75.12  ? 308 LEU B CD1 1 
ATOM 4366 C CD2 . LEU B 2 318 ? 130.760 104.363 141.742 1.00 70.20  ? 308 LEU B CD2 1 
ATOM 4367 N N   . ALA B 2 319 ? 131.829 109.229 138.778 1.00 68.64  ? 309 ALA B N   1 
ATOM 4368 C CA  . ALA B 2 319 ? 131.345 110.451 138.138 1.00 72.98  ? 309 ALA B CA  1 
ATOM 4369 C C   . ALA B 2 319 ? 130.604 110.077 136.861 1.00 73.44  ? 309 ALA B C   1 
ATOM 4370 O O   . ALA B 2 319 ? 131.229 109.784 135.838 1.00 81.03  ? 309 ALA B O   1 
ATOM 4371 C CB  . ALA B 2 319 ? 132.498 111.406 137.848 1.00 73.42  ? 309 ALA B CB  1 
ATOM 4372 N N   . GLY B 2 320 ? 129.277 110.082 136.918 1.00 69.33  ? 310 GLY B N   1 
ATOM 4373 C CA  . GLY B 2 320 ? 128.497 109.764 135.741 1.00 74.96  ? 310 GLY B CA  1 
ATOM 4374 C C   . GLY B 2 320 ? 127.189 110.514 135.611 1.00 82.60  ? 310 GLY B C   1 
ATOM 4375 O O   . GLY B 2 320 ? 126.309 110.083 134.860 1.00 94.84  ? 310 GLY B O   1 
ATOM 4376 N N   . HIS B 2 321 ? 127.037 111.631 136.317 1.00 74.62  ? 311 HIS B N   1 
ATOM 4377 C CA  . HIS B 2 321 ? 125.764 112.332 136.371 1.00 80.79  ? 311 HIS B CA  1 
ATOM 4378 C C   . HIS B 2 321 ? 125.904 113.764 135.886 1.00 86.19  ? 311 HIS B C   1 
ATOM 4379 O O   . HIS B 2 321 ? 126.891 114.442 136.184 1.00 86.19  ? 311 HIS B O   1 
ATOM 4380 C CB  . HIS B 2 321 ? 125.200 112.334 137.780 1.00 82.22  ? 311 HIS B CB  1 
ATOM 4381 C CG  . HIS B 2 321 ? 124.897 110.969 138.298 1.00 84.89  ? 311 HIS B CG  1 
ATOM 4382 N ND1 . HIS B 2 321 ? 123.926 110.164 137.747 1.00 87.66  ? 311 HIS B ND1 1 
ATOM 4383 C CD2 . HIS B 2 321 ? 125.441 110.263 139.315 1.00 86.78  ? 311 HIS B CD2 1 
ATOM 4384 C CE1 . HIS B 2 321 ? 123.883 109.020 138.404 1.00 89.17  ? 311 HIS B CE1 1 
ATOM 4385 N NE2 . HIS B 2 321 ? 124.794 109.054 139.359 1.00 92.02  ? 311 HIS B NE2 1 
ATOM 4386 N N   . ASP B 2 322 ? 124.899 114.213 135.141 1.00 95.26  ? 312 ASP B N   1 
ATOM 4387 C CA  . ASP B 2 322 ? 124.804 115.597 134.709 1.00 104.74 ? 312 ASP B CA  1 
ATOM 4388 C C   . ASP B 2 322 ? 124.163 116.485 135.765 1.00 102.76 ? 312 ASP B C   1 
ATOM 4389 O O   . ASP B 2 322 ? 124.038 117.694 135.549 1.00 109.92 ? 312 ASP B O   1 
ATOM 4390 C CB  . ASP B 2 322 ? 124.006 115.671 133.401 1.00 118.72 ? 312 ASP B CB  1 
ATOM 4391 C CG  . ASP B 2 322 ? 124.588 116.660 132.410 1.00 130.55 ? 312 ASP B CG  1 
ATOM 4392 O OD1 . ASP B 2 322 ? 124.730 117.847 132.768 1.00 134.64 ? 312 ASP B OD1 1 
ATOM 4393 O OD2 . ASP B 2 322 ? 124.900 116.255 131.270 1.00 135.39 ? 312 ASP B OD2 1 
ATOM 4394 N N   . ASN B 2 323 ? 123.760 115.922 136.896 1.00 96.03  ? 313 ASN B N   1 
ATOM 4395 C CA  . ASN B 2 323 ? 123.057 116.682 137.914 1.00 87.81  ? 313 ASN B CA  1 
ATOM 4396 C C   . ASN B 2 323 ? 123.427 116.116 139.282 1.00 84.62  ? 313 ASN B C   1 
ATOM 4397 O O   . ASN B 2 323 ? 124.472 115.476 139.439 1.00 89.65  ? 313 ASN B O   1 
ATOM 4398 C CB  . ASN B 2 323 ? 121.547 116.677 137.650 1.00 87.97  ? 313 ASN B CB  1 
ATOM 4399 C CG  . ASN B 2 323 ? 120.905 117.975 138.039 1.00 87.55  ? 313 ASN B CG  1 
ATOM 4400 O OD1 . ASN B 2 323 ? 121.303 118.607 139.008 1.00 86.37  ? 313 ASN B OD1 1 
ATOM 4401 N ND2 . ASN B 2 323 ? 119.893 118.384 137.280 1.00 89.95  ? 313 ASN B ND2 1 
ATOM 4402 N N   . ARG B 2 324 ? 122.584 116.392 140.277 1.00 80.37  ? 314 ARG B N   1 
ATOM 4403 C CA  . ARG B 2 324 ? 122.683 115.889 141.644 1.00 78.56  ? 314 ARG B CA  1 
ATOM 4404 C C   . ARG B 2 324 ? 122.860 114.384 141.760 1.00 81.41  ? 314 ARG B C   1 
ATOM 4405 O O   . ARG B 2 324 ? 122.555 113.640 140.826 1.00 90.03  ? 314 ARG B O   1 
ATOM 4406 C CB  . ARG B 2 324 ? 121.417 116.273 142.405 1.00 82.48  ? 314 ARG B CB  1 
ATOM 4407 C CG  . ARG B 2 324 ? 121.354 117.701 142.833 1.00 84.70  ? 314 ARG B CG  1 
ATOM 4408 C CD  . ARG B 2 324 ? 121.971 117.835 144.189 1.00 84.96  ? 314 ARG B CD  1 
ATOM 4409 N NE  . ARG B 2 324 ? 121.140 117.209 145.210 1.00 92.46  ? 314 ARG B NE  1 
ATOM 4410 C CZ  . ARG B 2 324 ? 120.768 117.803 146.334 1.00 91.24  ? 314 ARG B CZ  1 
ATOM 4411 N NH1 . ARG B 2 324 ? 121.207 119.008 146.655 1.00 87.16  ? 314 ARG B NH1 1 
ATOM 4412 N NH2 . ARG B 2 324 ? 119.943 117.170 147.164 1.00 88.35  ? 314 ARG B NH2 1 
ATOM 4413 N N   . VAL B 2 325 ? 123.360 113.929 142.904 1.00 71.58  ? 315 VAL B N   1 
ATOM 4414 C CA  . VAL B 2 325 ? 123.235 112.531 143.285 1.00 73.59  ? 315 VAL B CA  1 
ATOM 4415 C C   . VAL B 2 325 ? 122.292 112.501 144.476 1.00 77.19  ? 315 VAL B C   1 
ATOM 4416 O O   . VAL B 2 325 ? 122.721 112.637 145.625 1.00 81.93  ? 315 VAL B O   1 
ATOM 4417 C CB  . VAL B 2 325 ? 124.601 111.907 143.614 1.00 81.82  ? 315 VAL B CB  1 
ATOM 4418 C CG1 . VAL B 2 325 ? 124.449 110.435 143.960 1.00 83.77  ? 315 VAL B CG1 1 
ATOM 4419 C CG2 . VAL B 2 325 ? 125.552 112.089 142.447 1.00 84.08  ? 315 VAL B CG2 1 
ATOM 4420 N N   . SER B 2 326 ? 120.997 112.346 144.206 1.00 78.33  ? 316 SER B N   1 
ATOM 4421 C CA  . SER B 2 326 ? 119.993 112.548 145.243 1.00 81.07  ? 316 SER B CA  1 
ATOM 4422 C C   . SER B 2 326 ? 119.938 111.385 146.222 1.00 82.94  ? 316 SER B C   1 
ATOM 4423 O O   . SER B 2 326 ? 119.732 111.592 147.424 1.00 87.88  ? 316 SER B O   1 
ATOM 4424 C CB  . SER B 2 326 ? 118.622 112.773 144.610 1.00 81.90  ? 316 SER B CB  1 
ATOM 4425 O OG  . SER B 2 326 ? 118.128 111.582 144.028 1.00 79.92  ? 316 SER B OG  1 
ATOM 4426 N N   . CYS B 2 327 ? 120.115 110.162 145.738 1.00 75.06  ? 317 CYS B N   1 
ATOM 4427 C CA  . CYS B 2 327 ? 120.021 108.992 146.590 1.00 68.84  ? 317 CYS B CA  1 
ATOM 4428 C C   . CYS B 2 327 ? 120.948 107.904 146.075 1.00 66.50  ? 317 CYS B C   1 
ATOM 4429 O O   . CYS B 2 327 ? 121.334 107.899 144.905 1.00 76.21  ? 317 CYS B O   1 
ATOM 4430 C CB  . CYS B 2 327 ? 118.583 108.491 146.666 1.00 76.61  ? 317 CYS B CB  1 
ATOM 4431 S SG  . CYS B 2 327 ? 118.230 107.207 145.492 1.00 89.85  ? 317 CYS B SG  1 
ATOM 4432 N N   . LEU B 2 328 ? 121.314 106.990 146.969 1.00 67.06  ? 318 LEU B N   1 
ATOM 4433 C CA  . LEU B 2 328 ? 122.282 105.950 146.648 1.00 73.36  ? 318 LEU B CA  1 
ATOM 4434 C C   . LEU B 2 328 ? 122.060 104.773 147.583 1.00 72.94  ? 318 LEU B C   1 
ATOM 4435 O O   . LEU B 2 328 ? 121.883 104.966 148.788 1.00 78.00  ? 318 LEU B O   1 
ATOM 4436 C CB  . LEU B 2 328 ? 123.712 106.489 146.768 1.00 77.82  ? 318 LEU B CB  1 
ATOM 4437 C CG  . LEU B 2 328 ? 124.929 105.573 146.687 1.00 77.12  ? 318 LEU B CG  1 
ATOM 4438 C CD1 . LEU B 2 328 ? 125.980 106.212 145.802 1.00 79.92  ? 318 LEU B CD1 1 
ATOM 4439 C CD2 . LEU B 2 328 ? 125.497 105.338 148.070 1.00 72.04  ? 318 LEU B CD2 1 
ATOM 4440 N N   . GLY B 2 329 ? 122.067 103.563 147.029 1.00 67.73  ? 319 GLY B N   1 
ATOM 4441 C CA  . GLY B 2 329 ? 121.841 102.374 147.820 1.00 65.60  ? 319 GLY B CA  1 
ATOM 4442 C C   . GLY B 2 329 ? 122.739 101.239 147.374 1.00 70.29  ? 319 GLY B C   1 
ATOM 4443 O O   . GLY B 2 329 ? 123.240 101.213 146.249 1.00 78.63  ? 319 GLY B O   1 
ATOM 4444 N N   . VAL B 2 330 ? 122.931 100.295 148.287 1.00 69.96  ? 320 VAL B N   1 
ATOM 4445 C CA  . VAL B 2 330 ? 123.773 99.127  148.075 1.00 75.57  ? 320 VAL B CA  1 
ATOM 4446 C C   . VAL B 2 330 ? 122.964 97.894  148.453 1.00 84.40  ? 320 VAL B C   1 
ATOM 4447 O O   . VAL B 2 330 ? 122.269 97.893  149.476 1.00 92.21  ? 320 VAL B O   1 
ATOM 4448 C CB  . VAL B 2 330 ? 125.076 99.229  148.899 1.00 78.57  ? 320 VAL B CB  1 
ATOM 4449 C CG1 . VAL B 2 330 ? 125.746 97.872  149.091 1.00 81.04  ? 320 VAL B CG1 1 
ATOM 4450 C CG2 . VAL B 2 330 ? 126.034 100.210 148.247 1.00 81.20  ? 320 VAL B CG2 1 
ATOM 4451 N N   . THR B 2 331 ? 123.034 96.856  147.617 1.00 79.05  ? 321 THR B N   1 
ATOM 4452 C CA  . THR B 2 331 ? 122.251 95.644  147.810 1.00 77.17  ? 321 THR B CA  1 
ATOM 4453 C C   . THR B 2 331 ? 122.655 94.914  149.086 1.00 85.49  ? 321 THR B C   1 
ATOM 4454 O O   . THR B 2 331 ? 123.723 95.144  149.659 1.00 93.63  ? 321 THR B O   1 
ATOM 4455 C CB  . THR B 2 331 ? 122.426 94.693  146.633 1.00 83.14  ? 321 THR B CB  1 
ATOM 4456 O OG1 . THR B 2 331 ? 123.621 93.927  146.820 1.00 89.94  ? 321 THR B OG1 1 
ATOM 4457 C CG2 . THR B 2 331 ? 122.542 95.466  145.346 1.00 83.11  ? 321 THR B CG2 1 
ATOM 4458 N N   . ASP B 2 332 ? 121.775 94.015  149.528 1.00 85.23  ? 322 ASP B N   1 
ATOM 4459 C CA  . ASP B 2 332 ? 122.064 93.220  150.713 1.00 95.22  ? 322 ASP B CA  1 
ATOM 4460 C C   . ASP B 2 332 ? 123.139 92.177  150.456 1.00 98.78  ? 322 ASP B C   1 
ATOM 4461 O O   . ASP B 2 332 ? 123.785 91.725  151.406 1.00 109.20 ? 322 ASP B O   1 
ATOM 4462 C CB  . ASP B 2 332 ? 120.793 92.539  151.216 1.00 97.84  ? 322 ASP B CB  1 
ATOM 4463 C CG  . ASP B 2 332 ? 119.760 93.528  151.712 1.00 105.74 ? 322 ASP B CG  1 
ATOM 4464 O OD1 . ASP B 2 332 ? 120.040 94.745  151.682 1.00 104.94 ? 322 ASP B OD1 1 
ATOM 4465 O OD2 . ASP B 2 332 ? 118.669 93.091  152.133 1.00 106.22 ? 322 ASP B OD2 1 
ATOM 4466 N N   . ASP B 2 333 ? 123.346 91.789  149.201 1.00 92.12  ? 323 ASP B N   1 
ATOM 4467 C CA  . ASP B 2 333 ? 124.368 90.807  148.876 1.00 98.85  ? 323 ASP B CA  1 
ATOM 4468 C C   . ASP B 2 333 ? 125.688 91.493  148.544 1.00 97.63  ? 323 ASP B C   1 
ATOM 4469 O O   . ASP B 2 333 ? 126.759 90.957  148.849 1.00 97.92  ? 323 ASP B O   1 
ATOM 4470 C CB  . ASP B 2 333 ? 123.870 89.936  147.713 1.00 103.95 ? 323 ASP B CB  1 
ATOM 4471 C CG  . ASP B 2 333 ? 124.667 88.644  147.523 1.00 121.72 ? 323 ASP B CG  1 
ATOM 4472 O OD1 . ASP B 2 333 ? 125.813 88.508  147.994 1.00 122.40 ? 323 ASP B OD1 1 
ATOM 4473 O OD2 . ASP B 2 333 ? 124.114 87.731  146.875 1.00 125.71 ? 323 ASP B OD2 1 
ATOM 4474 N N   . GLY B 2 334 ? 125.635 92.703  147.997 1.00 96.15  ? 324 GLY B N   1 
ATOM 4475 C CA  . GLY B 2 334 ? 126.818 93.511  147.798 1.00 92.58  ? 324 GLY B CA  1 
ATOM 4476 C C   . GLY B 2 334 ? 127.397 93.525  146.403 1.00 92.16  ? 324 GLY B C   1 
ATOM 4477 O O   . GLY B 2 334 ? 128.499 94.054  146.220 1.00 93.72  ? 324 GLY B O   1 
ATOM 4478 N N   . MET B 2 335 ? 126.705 92.970  145.413 1.00 86.19  ? 325 MET B N   1 
ATOM 4479 C CA  . MET B 2 335 ? 127.227 92.896  144.057 1.00 81.78  ? 325 MET B CA  1 
ATOM 4480 C C   . MET B 2 335 ? 126.807 94.063  143.180 1.00 79.59  ? 325 MET B C   1 
ATOM 4481 O O   . MET B 2 335 ? 127.077 94.037  141.977 1.00 88.00  ? 325 MET B O   1 
ATOM 4482 C CB  . MET B 2 335 ? 126.817 91.581  143.393 1.00 86.34  ? 325 MET B CB  1 
ATOM 4483 C CG  . MET B 2 335 ? 127.616 90.381  143.853 1.00 93.66  ? 325 MET B CG  1 
ATOM 4484 S SD  . MET B 2 335 ? 126.683 89.186  144.820 1.00 124.38 ? 325 MET B SD  1 
ATOM 4485 C CE  . MET B 2 335 ? 125.486 88.609  143.622 1.00 107.19 ? 325 MET B CE  1 
ATOM 4486 N N   . ALA B 2 336 ? 126.153 95.078  143.736 1.00 74.24  ? 326 ALA B N   1 
ATOM 4487 C CA  . ALA B 2 336 ? 125.773 96.228  142.931 1.00 75.08  ? 326 ALA B CA  1 
ATOM 4488 C C   . ALA B 2 336 ? 125.686 97.464  143.808 1.00 73.44  ? 326 ALA B C   1 
ATOM 4489 O O   . ALA B 2 336 ? 125.364 97.383  144.995 1.00 77.47  ? 326 ALA B O   1 
ATOM 4490 C CB  . ALA B 2 336 ? 124.438 96.007  142.211 1.00 74.93  ? 326 ALA B CB  1 
ATOM 4491 N N   . VAL B 2 337 ? 125.987 98.607  143.203 1.00 74.98  ? 327 VAL B N   1 
ATOM 4492 C CA  . VAL B 2 337 ? 125.813 99.915  143.819 1.00 70.72  ? 327 VAL B CA  1 
ATOM 4493 C C   . VAL B 2 337 ? 124.883 100.715 142.928 1.00 68.82  ? 327 VAL B C   1 
ATOM 4494 O O   . VAL B 2 337 ? 125.152 100.881 141.733 1.00 74.06  ? 327 VAL B O   1 
ATOM 4495 C CB  . VAL B 2 337 ? 127.152 100.649 143.996 1.00 70.63  ? 327 VAL B CB  1 
ATOM 4496 C CG1 . VAL B 2 337 ? 126.918 102.111 144.335 1.00 71.25  ? 327 VAL B CG1 1 
ATOM 4497 C CG2 . VAL B 2 337 ? 127.972 99.980  145.057 1.00 76.19  ? 327 VAL B CG2 1 
ATOM 4498 N N   . ALA B 2 338 ? 123.800 101.209 143.501 1.00 65.83  ? 328 ALA B N   1 
ATOM 4499 C CA  . ALA B 2 338 ? 122.786 101.920 142.749 1.00 65.24  ? 328 ALA B CA  1 
ATOM 4500 C C   . ALA B 2 338 ? 122.798 103.388 143.133 1.00 69.87  ? 328 ALA B C   1 
ATOM 4501 O O   . ALA B 2 338 ? 123.030 103.740 144.292 1.00 80.15  ? 328 ALA B O   1 
ATOM 4502 C CB  . ALA B 2 338 ? 121.406 101.325 143.003 1.00 68.83  ? 328 ALA B CB  1 
ATOM 4503 N N   . THR B 2 339 ? 122.556 104.244 142.149 1.00 70.11  ? 329 THR B N   1 
ATOM 4504 C CA  . THR B 2 339 ? 122.558 105.675 142.386 1.00 73.36  ? 329 THR B CA  1 
ATOM 4505 C C   . THR B 2 339 ? 121.349 106.309 141.720 1.00 79.03  ? 329 THR B C   1 
ATOM 4506 O O   . THR B 2 339 ? 120.889 105.880 140.659 1.00 82.18  ? 329 THR B O   1 
ATOM 4507 C CB  . THR B 2 339 ? 123.846 106.332 141.883 1.00 75.19  ? 329 THR B CB  1 
ATOM 4508 O OG1 . THR B 2 339 ? 123.748 107.753 142.026 1.00 82.82  ? 329 THR B OG1 1 
ATOM 4509 C CG2 . THR B 2 339 ? 124.087 105.987 140.433 1.00 75.77  ? 329 THR B CG2 1 
ATOM 4510 N N   . GLY B 2 340 ? 120.820 107.331 142.386 1.00 83.03  ? 330 GLY B N   1 
ATOM 4511 C CA  . GLY B 2 340 ? 119.771 108.145 141.825 1.00 80.64  ? 330 GLY B CA  1 
ATOM 4512 C C   . GLY B 2 340 ? 120.313 109.531 141.538 1.00 81.19  ? 330 GLY B C   1 
ATOM 4513 O O   . GLY B 2 340 ? 121.319 109.957 142.110 1.00 88.00  ? 330 GLY B O   1 
ATOM 4514 N N   . SER B 2 341 ? 119.632 110.228 140.641 1.00 78.50  ? 331 SER B N   1 
ATOM 4515 C CA  . SER B 2 341 ? 120.138 111.514 140.208 1.00 81.26  ? 331 SER B CA  1 
ATOM 4516 C C   . SER B 2 341 ? 118.989 112.400 139.769 1.00 78.88  ? 331 SER B C   1 
ATOM 4517 O O   . SER B 2 341 ? 117.883 111.931 139.495 1.00 85.62  ? 331 SER B O   1 
ATOM 4518 C CB  . SER B 2 341 ? 121.141 111.353 139.071 1.00 88.16  ? 331 SER B CB  1 
ATOM 4519 O OG  . SER B 2 341 ? 121.066 112.457 138.196 1.00 90.63  ? 331 SER B OG  1 
ATOM 4520 N N   . TRP B 2 342 ? 119.271 113.694 139.694 1.00 73.21  ? 332 TRP B N   1 
ATOM 4521 C CA  . TRP B 2 342 ? 118.287 114.651 139.221 1.00 75.46  ? 332 TRP B CA  1 
ATOM 4522 C C   . TRP B 2 342 ? 118.247 114.763 137.705 1.00 83.57  ? 332 TRP B C   1 
ATOM 4523 O O   . TRP B 2 342 ? 117.428 115.528 137.187 1.00 89.20  ? 332 TRP B O   1 
ATOM 4524 C CB  . TRP B 2 342 ? 118.547 116.030 139.829 1.00 77.25  ? 332 TRP B CB  1 
ATOM 4525 C CG  . TRP B 2 342 ? 118.090 116.164 141.239 1.00 80.03  ? 332 TRP B CG  1 
ATOM 4526 C CD1 . TRP B 2 342 ? 117.708 115.161 142.073 1.00 84.88  ? 332 TRP B CD1 1 
ATOM 4527 C CD2 . TRP B 2 342 ? 117.949 117.378 141.981 1.00 82.01  ? 332 TRP B CD2 1 
ATOM 4528 N NE1 . TRP B 2 342 ? 117.347 115.671 143.293 1.00 87.50  ? 332 TRP B NE1 1 
ATOM 4529 C CE2 . TRP B 2 342 ? 117.486 117.032 143.261 1.00 82.38  ? 332 TRP B CE2 1 
ATOM 4530 C CE3 . TRP B 2 342 ? 118.169 118.725 141.686 1.00 82.52  ? 332 TRP B CE3 1 
ATOM 4531 C CZ2 . TRP B 2 342 ? 117.243 117.980 144.246 1.00 80.49  ? 332 TRP B CZ2 1 
ATOM 4532 C CZ3 . TRP B 2 342 ? 117.933 119.663 142.667 1.00 83.79  ? 332 TRP B CZ3 1 
ATOM 4533 C CH2 . TRP B 2 342 ? 117.471 119.288 143.930 1.00 83.58  ? 332 TRP B CH2 1 
ATOM 4534 N N   . ASP B 2 343 ? 119.097 114.039 136.978 1.00 81.46  ? 333 ASP B N   1 
ATOM 4535 C CA  . ASP B 2 343 ? 118.965 113.997 135.528 1.00 85.39  ? 333 ASP B CA  1 
ATOM 4536 C C   . ASP B 2 343 ? 118.155 112.801 135.043 1.00 81.55  ? 333 ASP B C   1 
ATOM 4537 O O   . ASP B 2 343 ? 118.383 112.328 133.925 1.00 81.69  ? 333 ASP B O   1 
ATOM 4538 C CB  . ASP B 2 343 ? 120.343 114.046 134.838 1.00 91.35  ? 333 ASP B CB  1 
ATOM 4539 C CG  . ASP B 2 343 ? 121.271 112.890 135.212 1.00 97.83  ? 333 ASP B CG  1 
ATOM 4540 O OD1 . ASP B 2 343 ? 120.850 111.900 135.845 1.00 97.58  ? 333 ASP B OD1 1 
ATOM 4541 O OD2 . ASP B 2 343 ? 122.464 112.979 134.854 1.00 102.75 ? 333 ASP B OD2 1 
ATOM 4542 N N   . SER B 2 344 ? 117.220 112.313 135.859 1.00 75.61  ? 334 SER B N   1 
ATOM 4543 C CA  . SER B 2 344 ? 116.278 111.218 135.608 1.00 78.89  ? 334 SER B CA  1 
ATOM 4544 C C   . SER B 2 344 ? 116.954 109.924 135.183 1.00 83.50  ? 334 SER B C   1 
ATOM 4545 O O   . SER B 2 344 ? 116.350 109.154 134.427 1.00 90.43  ? 334 SER B O   1 
ATOM 4546 C CB  . SER B 2 344 ? 115.209 111.554 134.558 1.00 85.40  ? 334 SER B CB  1 
ATOM 4547 O OG  . SER B 2 344 ? 115.698 112.294 133.453 1.00 88.55  ? 334 SER B OG  1 
ATOM 4548 N N   . PHE B 2 345 ? 118.171 109.650 135.638 1.00 80.60  ? 335 PHE B N   1 
ATOM 4549 C CA  . PHE B 2 345 ? 118.901 108.467 135.208 1.00 81.48  ? 335 PHE B CA  1 
ATOM 4550 C C   . PHE B 2 345 ? 119.371 107.697 136.430 1.00 81.62  ? 335 PHE B C   1 
ATOM 4551 O O   . PHE B 2 345 ? 120.025 108.266 137.310 1.00 88.11  ? 335 PHE B O   1 
ATOM 4552 C CB  . PHE B 2 345 ? 120.103 108.851 134.342 1.00 82.26  ? 335 PHE B CB  1 
ATOM 4553 C CG  . PHE B 2 345 ? 119.747 109.200 132.929 1.00 88.05  ? 335 PHE B CG  1 
ATOM 4554 C CD1 . PHE B 2 345 ? 118.650 108.627 132.307 1.00 93.71  ? 335 PHE B CD1 1 
ATOM 4555 C CD2 . PHE B 2 345 ? 120.507 110.115 132.224 1.00 88.06  ? 335 PHE B CD2 1 
ATOM 4556 C CE1 . PHE B 2 345 ? 118.318 108.965 131.006 1.00 98.00  ? 335 PHE B CE1 1 
ATOM 4557 C CE2 . PHE B 2 345 ? 120.185 110.451 130.924 1.00 97.25  ? 335 PHE B CE2 1 
ATOM 4558 C CZ  . PHE B 2 345 ? 119.090 109.874 130.313 1.00 103.20 ? 335 PHE B CZ  1 
ATOM 4559 N N   . LEU B 2 346 ? 119.046 106.412 136.483 1.00 76.44  ? 336 LEU B N   1 
ATOM 4560 C CA  . LEU B 2 346 ? 119.641 105.515 137.460 1.00 74.84  ? 336 LEU B CA  1 
ATOM 4561 C C   . LEU B 2 346 ? 120.818 104.797 136.828 1.00 77.54  ? 336 LEU B C   1 
ATOM 4562 O O   . LEU B 2 346 ? 120.789 104.460 135.643 1.00 85.22  ? 336 LEU B O   1 
ATOM 4563 C CB  . LEU B 2 346 ? 118.639 104.479 137.957 1.00 75.63  ? 336 LEU B CB  1 
ATOM 4564 C CG  . LEU B 2 346 ? 117.353 104.957 138.602 1.00 79.36  ? 336 LEU B CG  1 
ATOM 4565 C CD1 . LEU B 2 346 ? 116.546 103.748 139.002 1.00 76.11  ? 336 LEU B CD1 1 
ATOM 4566 C CD2 . LEU B 2 346 ? 117.679 105.818 139.798 1.00 78.05  ? 336 LEU B CD2 1 
ATOM 4567 N N   . LYS B 2 347 ? 121.853 104.563 137.621 1.00 67.48  ? 337 LYS B N   1 
ATOM 4568 C CA  . LYS B 2 347 ? 123.014 103.824 137.162 1.00 65.47  ? 337 LYS B CA  1 
ATOM 4569 C C   . LYS B 2 347 ? 123.353 102.741 138.173 1.00 66.29  ? 337 LYS B C   1 
ATOM 4570 O O   . LYS B 2 347 ? 123.174 102.917 139.380 1.00 74.46  ? 337 LYS B O   1 
ATOM 4571 C CB  . LYS B 2 347 ? 124.220 104.742 136.945 1.00 68.17  ? 337 LYS B CB  1 
ATOM 4572 C CG  . LYS B 2 347 ? 123.979 105.856 135.947 1.00 73.24  ? 337 LYS B CG  1 
ATOM 4573 C CD  . LYS B 2 347 ? 125.269 106.363 135.349 1.00 77.82  ? 337 LYS B CD  1 
ATOM 4574 C CE  . LYS B 2 347 ? 125.047 106.863 133.937 1.00 74.31  ? 337 LYS B CE  1 
ATOM 4575 N NZ  . LYS B 2 347 ? 124.801 108.328 133.907 1.00 81.74  ? 337 LYS B NZ  1 
ATOM 4576 N N   . ILE B 2 348 ? 123.837 101.615 137.665 1.00 66.01  ? 338 ILE B N   1 
ATOM 4577 C CA  . ILE B 2 348 ? 124.284 100.502 138.490 1.00 63.43  ? 338 ILE B CA  1 
ATOM 4578 C C   . ILE B 2 348 ? 125.787 100.374 138.312 1.00 72.22  ? 338 ILE B C   1 
ATOM 4579 O O   . ILE B 2 348 ? 126.276 100.225 137.185 1.00 80.44  ? 338 ILE B O   1 
ATOM 4580 C CB  . ILE B 2 348 ? 123.574 99.194  138.114 1.00 62.71  ? 338 ILE B CB  1 
ATOM 4581 C CG1 . ILE B 2 348 ? 122.093 99.259  138.478 1.00 67.33  ? 338 ILE B CG1 1 
ATOM 4582 C CG2 . ILE B 2 348 ? 124.244 98.015  138.799 1.00 67.75  ? 338 ILE B CG2 1 
ATOM 4583 C CD1 . ILE B 2 348 ? 121.829 99.265  139.954 1.00 74.52  ? 338 ILE B CD1 1 
ATOM 4584 N N   . TRP B 2 349 ? 126.520 100.431 139.417 1.00 68.94  ? 339 TRP B N   1 
ATOM 4585 C CA  . TRP B 2 349 ? 127.965 100.281 139.415 1.00 67.09  ? 339 TRP B CA  1 
ATOM 4586 C C   . TRP B 2 349 ? 128.350 98.942  140.021 1.00 72.63  ? 339 TRP B C   1 
ATOM 4587 O O   . TRP B 2 349 ? 127.698 98.459  140.951 1.00 77.60  ? 339 TRP B O   1 
ATOM 4588 C CB  . TRP B 2 349 ? 128.639 101.407 140.195 1.00 67.37  ? 339 TRP B CB  1 
ATOM 4589 C CG  . TRP B 2 349 ? 128.192 102.774 139.816 1.00 66.98  ? 339 TRP B CG  1 
ATOM 4590 C CD1 . TRP B 2 349 ? 127.102 103.434 140.281 1.00 67.69  ? 339 TRP B CD1 1 
ATOM 4591 C CD2 . TRP B 2 349 ? 128.861 103.678 138.930 1.00 72.98  ? 339 TRP B CD2 1 
ATOM 4592 N NE1 . TRP B 2 349 ? 127.033 104.683 139.723 1.00 70.19  ? 339 TRP B NE1 1 
ATOM 4593 C CE2 . TRP B 2 349 ? 128.104 104.859 138.892 1.00 70.75  ? 339 TRP B CE2 1 
ATOM 4594 C CE3 . TRP B 2 349 ? 130.027 103.600 138.164 1.00 77.54  ? 339 TRP B CE3 1 
ATOM 4595 C CZ2 . TRP B 2 349 ? 128.464 105.950 138.114 1.00 72.42  ? 339 TRP B CZ2 1 
ATOM 4596 C CZ3 . TRP B 2 349 ? 130.383 104.686 137.392 1.00 78.11  ? 339 TRP B CZ3 1 
ATOM 4597 C CH2 . TRP B 2 349 ? 129.607 105.847 137.377 1.00 77.87  ? 339 TRP B CH2 1 
ATOM 4598 N N   . ASN B 2 350 ? 129.410 98.349  139.490 1.00 77.56  ? 340 ASN B N   1 
ATOM 4599 C CA  . ASN B 2 350 ? 129.928 97.093  140.009 1.00 85.23  ? 340 ASN B CA  1 
ATOM 4600 C C   . ASN B 2 350 ? 131.431 96.994  139.777 1.00 90.54  ? 340 ASN B C   1 
ATOM 4601 O O   . ASN B 2 350 ? 131.922 97.304  138.691 1.00 91.07  ? 340 ASN B O   1 
ATOM 4602 C CB  . ASN B 2 350 ? 129.217 95.911  139.362 1.00 88.38  ? 340 ASN B CB  1 
ATOM 4603 C CG  . ASN B 2 350 ? 129.504 94.606  140.066 1.00 95.70  ? 340 ASN B CG  1 
ATOM 4604 O OD1 . ASN B 2 350 ? 130.039 94.588  141.173 1.00 102.23 ? 340 ASN B OD1 1 
ATOM 4605 N ND2 . ASN B 2 350 ? 129.147 93.501  139.427 1.00 93.53  ? 340 ASN B ND2 1 
ATOM 4606 N N   . LYS C 3 8   ? 113.733 72.237  130.526 1.00 140.71 ? 8   LYS C N   1 
ATOM 4607 C CA  . LYS C 3 8   ? 113.169 73.326  131.315 1.00 142.04 ? 8   LYS C CA  1 
ATOM 4608 C C   . LYS C 3 8   ? 113.514 74.680  130.705 1.00 141.65 ? 8   LYS C C   1 
ATOM 4609 O O   . LYS C 3 8   ? 113.364 75.718  131.349 1.00 139.78 ? 8   LYS C O   1 
ATOM 4610 C CB  . LYS C 3 8   ? 113.669 73.256  132.759 1.00 138.77 ? 8   LYS C CB  1 
ATOM 4611 N N   . THR C 3 9   ? 113.984 74.659  129.455 1.00 142.79 ? 9   THR C N   1 
ATOM 4612 C CA  . THR C 3 9   ? 114.324 75.902  128.772 1.00 141.15 ? 9   THR C CA  1 
ATOM 4613 C C   . THR C 3 9   ? 113.081 76.703  128.406 1.00 138.94 ? 9   THR C C   1 
ATOM 4614 O O   . THR C 3 9   ? 113.132 77.938  128.358 1.00 134.47 ? 9   THR C O   1 
ATOM 4615 C CB  . THR C 3 9   ? 115.148 75.610  127.518 1.00 141.94 ? 9   THR C CB  1 
ATOM 4616 O OG1 . THR C 3 9   ? 114.334 74.927  126.557 1.00 144.40 ? 9   THR C OG1 1 
ATOM 4617 C CG2 . THR C 3 9   ? 116.351 74.744  127.863 1.00 139.66 ? 9   THR C CG2 1 
ATOM 4618 N N   . GLU C 3 10  ? 111.961 76.020  128.153 1.00 141.34 ? 10  GLU C N   1 
ATOM 4619 C CA  . GLU C 3 10  ? 110.739 76.708  127.753 1.00 140.15 ? 10  GLU C CA  1 
ATOM 4620 C C   . GLU C 3 10  ? 110.168 77.552  128.884 1.00 136.51 ? 10  GLU C C   1 
ATOM 4621 O O   . GLU C 3 10  ? 109.584 78.610  128.627 1.00 134.64 ? 10  GLU C O   1 
ATOM 4622 C CB  . GLU C 3 10  ? 109.703 75.691  127.271 1.00 140.16 ? 10  GLU C CB  1 
ATOM 4623 C CG  . GLU C 3 10  ? 108.523 76.298  126.529 1.00 142.20 ? 10  GLU C CG  1 
ATOM 4624 C CD  . GLU C 3 10  ? 108.912 76.853  125.172 1.00 144.79 ? 10  GLU C CD  1 
ATOM 4625 O OE1 . GLU C 3 10  ? 109.323 76.059  124.300 1.00 147.04 ? 10  GLU C OE1 1 
ATOM 4626 O OE2 . GLU C 3 10  ? 108.807 78.082  124.979 1.00 141.36 ? 10  GLU C OE2 1 
ATOM 4627 N N   . ASP C 3 11  ? 110.347 77.114  130.134 1.00 135.78 ? 11  ASP C N   1 
ATOM 4628 C CA  . ASP C 3 11  ? 109.789 77.834  131.276 1.00 133.88 ? 11  ASP C CA  1 
ATOM 4629 C C   . ASP C 3 11  ? 110.428 79.210  131.438 1.00 133.41 ? 11  ASP C C   1 
ATOM 4630 O O   . ASP C 3 11  ? 109.733 80.232  131.462 1.00 134.15 ? 11  ASP C O   1 
ATOM 4631 C CB  . ASP C 3 11  ? 109.962 77.005  132.549 1.00 136.73 ? 11  ASP C CB  1 
ATOM 4632 C CG  . ASP C 3 11  ? 109.731 75.525  132.315 1.00 141.70 ? 11  ASP C CG  1 
ATOM 4633 O OD1 . ASP C 3 11  ? 108.915 75.181  131.434 1.00 141.24 ? 11  ASP C OD1 1 
ATOM 4634 O OD2 . ASP C 3 11  ? 110.365 74.705  133.012 1.00 143.85 ? 11  ASP C OD2 1 
ATOM 4635 N N   . GLN C 3 12  ? 111.759 79.269  131.502 1.00 133.37 ? 12  GLN C N   1 
ATOM 4636 C CA  . GLN C 3 12  ? 112.373 80.586  131.609 1.00 132.45 ? 12  GLN C CA  1 
ATOM 4637 C C   . GLN C 3 12  ? 112.353 81.328  130.279 1.00 129.74 ? 12  GLN C C   1 
ATOM 4638 O O   . GLN C 3 12  ? 112.373 82.561  130.284 1.00 127.68 ? 12  GLN C O   1 
ATOM 4639 C CB  . GLN C 3 12  ? 113.797 80.495  132.170 1.00 131.87 ? 12  GLN C CB  1 
ATOM 4640 C CG  . GLN C 3 12  ? 114.921 80.481  131.155 1.00 131.08 ? 12  GLN C CG  1 
ATOM 4641 C CD  . GLN C 3 12  ? 115.029 79.167  130.430 1.00 133.59 ? 12  GLN C CD  1 
ATOM 4642 O OE1 . GLN C 3 12  ? 115.111 78.110  131.054 1.00 134.18 ? 12  GLN C OE1 1 
ATOM 4643 N NE2 . GLN C 3 12  ? 115.035 79.220  129.103 1.00 132.04 ? 12  GLN C NE2 1 
ATOM 4644 N N   . ARG C 3 13  ? 112.246 80.613  129.153 1.00 130.74 ? 13  ARG C N   1 
ATOM 4645 C CA  . ARG C 3 13  ? 112.103 81.276  127.860 1.00 130.98 ? 13  ARG C CA  1 
ATOM 4646 C C   . ARG C 3 13  ? 110.809 82.081  127.792 1.00 127.32 ? 13  ARG C C   1 
ATOM 4647 O O   . ARG C 3 13  ? 110.823 83.279  127.481 1.00 126.61 ? 13  ARG C O   1 
ATOM 4648 C CB  . ARG C 3 13  ? 112.157 80.243  126.734 1.00 135.64 ? 13  ARG C CB  1 
ATOM 4649 C CG  . ARG C 3 13  ? 113.470 80.231  125.967 1.00 137.10 ? 13  ARG C CG  1 
ATOM 4650 C CD  . ARG C 3 13  ? 113.323 79.517  124.633 1.00 138.95 ? 13  ARG C CD  1 
ATOM 4651 N NE  . ARG C 3 13  ? 113.202 78.074  124.799 1.00 143.56 ? 13  ARG C NE  1 
ATOM 4652 C CZ  . ARG C 3 13  ? 112.319 77.318  124.161 1.00 144.69 ? 13  ARG C CZ  1 
ATOM 4653 N NH1 . ARG C 3 13  ? 111.459 77.836  123.300 1.00 143.89 ? 13  ARG C NH1 1 
ATOM 4654 N NH2 . ARG C 3 13  ? 112.300 76.008  124.392 1.00 144.59 ? 13  ARG C NH2 1 
ATOM 4655 N N   . ASN C 3 14  ? 109.678 81.455  128.125 1.00 126.05 ? 14  ASN C N   1 
ATOM 4656 C CA  . ASN C 3 14  ? 108.437 82.215  128.145 1.00 123.75 ? 14  ASN C CA  1 
ATOM 4657 C C   . ASN C 3 14  ? 108.334 83.127  129.359 1.00 124.78 ? 14  ASN C C   1 
ATOM 4658 O O   . ASN C 3 14  ? 107.548 84.079  129.321 1.00 122.74 ? 14  ASN C O   1 
ATOM 4659 C CB  . ASN C 3 14  ? 107.213 81.291  128.057 1.00 125.47 ? 14  ASN C CB  1 
ATOM 4660 C CG  . ASN C 3 14  ? 106.745 80.788  129.407 1.00 129.82 ? 14  ASN C CG  1 
ATOM 4661 O OD1 . ASN C 3 14  ? 107.373 79.927  130.014 1.00 134.39 ? 14  ASN C OD1 1 
ATOM 4662 N ND2 . ASN C 3 14  ? 105.629 81.328  129.882 1.00 126.88 ? 14  ASN C ND2 1 
ATOM 4663 N N   . GLU C 3 15  ? 109.145 82.907  130.401 1.00 126.38 ? 15  GLU C N   1 
ATOM 4664 C CA  . GLU C 3 15  ? 109.235 83.886  131.481 1.00 128.33 ? 15  GLU C CA  1 
ATOM 4665 C C   . GLU C 3 15  ? 109.820 85.206  130.986 1.00 126.33 ? 15  GLU C C   1 
ATOM 4666 O O   . GLU C 3 15  ? 109.240 86.274  131.213 1.00 123.83 ? 15  GLU C O   1 
ATOM 4667 C CB  . GLU C 3 15  ? 110.069 83.323  132.634 1.00 130.64 ? 15  GLU C CB  1 
ATOM 4668 C CG  . GLU C 3 15  ? 109.846 83.991  133.995 1.00 133.88 ? 15  GLU C CG  1 
ATOM 4669 C CD  . GLU C 3 15  ? 108.389 84.028  134.450 1.00 137.80 ? 15  GLU C CD  1 
ATOM 4670 O OE1 . GLU C 3 15  ? 107.616 83.098  134.129 1.00 136.56 ? 15  GLU C OE1 1 
ATOM 4671 O OE2 . GLU C 3 15  ? 108.015 85.001  135.137 1.00 140.25 ? 15  GLU C OE2 1 
ATOM 4672 N N   . GLU C 3 16  ? 110.965 85.156  130.293 1.00 126.64 ? 16  GLU C N   1 
ATOM 4673 C CA  . GLU C 3 16  ? 111.497 86.394  129.721 1.00 122.39 ? 16  GLU C CA  1 
ATOM 4674 C C   . GLU C 3 16  ? 110.642 86.912  128.571 1.00 117.63 ? 16  GLU C C   1 
ATOM 4675 O O   . GLU C 3 16  ? 110.638 88.120  128.317 1.00 116.36 ? 16  GLU C O   1 
ATOM 4676 C CB  . GLU C 3 16  ? 112.951 86.248  129.258 1.00 121.88 ? 16  GLU C CB  1 
ATOM 4677 C CG  . GLU C 3 16  ? 113.829 85.319  130.064 1.00 126.02 ? 16  GLU C CG  1 
ATOM 4678 C CD  . GLU C 3 16  ? 113.973 85.755  131.509 1.00 129.85 ? 16  GLU C CD  1 
ATOM 4679 O OE1 . GLU C 3 16  ? 114.854 86.594  131.792 1.00 128.38 ? 16  GLU C OE1 1 
ATOM 4680 O OE2 . GLU C 3 16  ? 113.210 85.256  132.363 1.00 132.12 ? 16  GLU C OE2 1 
ATOM 4681 N N   . LYS C 3 17  ? 109.906 86.039  127.878 1.00 116.53 ? 17  LYS C N   1 
ATOM 4682 C CA  . LYS C 3 17  ? 108.968 86.516  126.864 1.00 112.93 ? 17  LYS C CA  1 
ATOM 4683 C C   . LYS C 3 17  ? 107.853 87.349  127.491 1.00 111.51 ? 17  LYS C C   1 
ATOM 4684 O O   . LYS C 3 17  ? 107.521 88.439  127.002 1.00 113.62 ? 17  LYS C O   1 
ATOM 4685 C CB  . LYS C 3 17  ? 108.387 85.332  126.092 1.00 114.52 ? 17  LYS C CB  1 
ATOM 4686 C CG  . LYS C 3 17  ? 108.172 85.600  124.604 1.00 113.66 ? 17  LYS C CG  1 
ATOM 4687 C CD  . LYS C 3 17  ? 108.169 84.322  123.755 1.00 109.82 ? 17  LYS C CD  1 
ATOM 4688 C CE  . LYS C 3 17  ? 107.341 83.169  124.336 1.00 108.66 ? 17  LYS C CE  1 
ATOM 4689 N NZ  . LYS C 3 17  ? 105.978 83.548  124.827 1.00 106.54 ? 17  LYS C NZ  1 
ATOM 4690 N N   . ALA C 3 18  ? 107.280 86.860  128.594 1.00 108.93 ? 18  ALA C N   1 
ATOM 4691 C CA  . ALA C 3 18  ? 106.260 87.623  129.304 1.00 109.51 ? 18  ALA C CA  1 
ATOM 4692 C C   . ALA C 3 18  ? 106.841 88.881  129.932 1.00 107.70 ? 18  ALA C C   1 
ATOM 4693 O O   . ALA C 3 18  ? 106.160 89.911  129.998 1.00 106.14 ? 18  ALA C O   1 
ATOM 4694 C CB  . ALA C 3 18  ? 105.597 86.752  130.370 1.00 109.48 ? 18  ALA C CB  1 
ATOM 4695 N N   . GLN C 3 19  ? 108.093 88.814  130.393 1.00 106.37 ? 19  GLN C N   1 
ATOM 4696 C CA  . GLN C 3 19  ? 108.750 89.996  130.939 1.00 106.97 ? 19  GLN C CA  1 
ATOM 4697 C C   . GLN C 3 19  ? 108.949 91.062  129.868 1.00 107.10 ? 19  GLN C C   1 
ATOM 4698 O O   . GLN C 3 19  ? 108.754 92.255  130.126 1.00 106.49 ? 19  GLN C O   1 
ATOM 4699 C CB  . GLN C 3 19  ? 110.083 89.601  131.567 1.00 106.08 ? 19  GLN C CB  1 
ATOM 4700 C CG  . GLN C 3 19  ? 110.793 90.730  132.279 1.00 106.66 ? 19  GLN C CG  1 
ATOM 4701 C CD  . GLN C 3 19  ? 111.605 90.245  133.458 1.00 109.70 ? 19  GLN C CD  1 
ATOM 4702 O OE1 . GLN C 3 19  ? 111.320 89.196  134.033 1.00 112.72 ? 19  GLN C OE1 1 
ATOM 4703 N NE2 . GLN C 3 19  ? 112.631 91.004  133.821 1.00 109.11 ? 19  GLN C NE2 1 
ATOM 4704 N N   . ARG C 3 20  ? 109.322 90.648  128.654 1.00 106.59 ? 20  ARG C N   1 
ATOM 4705 C CA  . ARG C 3 20  ? 109.457 91.590  127.549 1.00 101.55 ? 20  ARG C CA  1 
ATOM 4706 C C   . ARG C 3 20  ? 108.108 92.171  127.146 1.00 97.19  ? 20  ARG C C   1 
ATOM 4707 O O   . ARG C 3 20  ? 108.020 93.349  126.783 1.00 99.55  ? 20  ARG C O   1 
ATOM 4708 C CB  . ARG C 3 20  ? 110.123 90.908  126.356 1.00 104.56 ? 20  ARG C CB  1 
ATOM 4709 C CG  . ARG C 3 20  ? 111.618 90.706  126.513 1.00 109.17 ? 20  ARG C CG  1 
ATOM 4710 C CD  . ARG C 3 20  ? 112.406 91.650  125.614 1.00 115.65 ? 20  ARG C CD  1 
ATOM 4711 N NE  . ARG C 3 20  ? 113.713 91.116  125.246 1.00 125.95 ? 20  ARG C NE  1 
ATOM 4712 C CZ  . ARG C 3 20  ? 114.767 91.064  126.051 1.00 127.86 ? 20  ARG C CZ  1 
ATOM 4713 N NH1 . ARG C 3 20  ? 114.724 91.545  127.284 1.00 125.52 ? 20  ARG C NH1 1 
ATOM 4714 N NH2 . ARG C 3 20  ? 115.898 90.526  125.604 1.00 129.32 ? 20  ARG C NH2 1 
ATOM 4715 N N   . GLU C 3 21  ? 107.049 91.358  127.191 1.00 95.21  ? 21  GLU C N   1 
ATOM 4716 C CA  . GLU C 3 21  ? 105.715 91.873  126.889 1.00 98.92  ? 21  GLU C CA  1 
ATOM 4717 C C   . GLU C 3 21  ? 105.274 92.906  127.922 1.00 99.15  ? 21  GLU C C   1 
ATOM 4718 O O   . GLU C 3 21  ? 104.688 93.943  127.571 1.00 102.99 ? 21  GLU C O   1 
ATOM 4719 C CB  . GLU C 3 21  ? 104.714 90.721  126.819 1.00 103.86 ? 21  GLU C CB  1 
ATOM 4720 C CG  . GLU C 3 21  ? 103.743 90.809  125.652 1.00 111.67 ? 21  GLU C CG  1 
ATOM 4721 C CD  . GLU C 3 21  ? 102.820 92.008  125.748 1.00 119.61 ? 21  GLU C CD  1 
ATOM 4722 O OE1 . GLU C 3 21  ? 101.990 92.047  126.680 1.00 118.13 ? 21  GLU C OE1 1 
ATOM 4723 O OE2 . GLU C 3 21  ? 102.925 92.911  124.891 1.00 122.74 ? 21  GLU C OE2 1 
ATOM 4724 N N   . ALA C 3 22  ? 105.557 92.641  129.200 1.00 95.48  ? 22  ALA C N   1 
ATOM 4725 C CA  . ALA C 3 22  ? 105.245 93.604  130.251 1.00 96.11  ? 22  ALA C CA  1 
ATOM 4726 C C   . ALA C 3 22  ? 106.069 94.874  130.093 1.00 94.80  ? 22  ALA C C   1 
ATOM 4727 O O   . ALA C 3 22  ? 105.570 95.979  130.338 1.00 95.50  ? 22  ALA C O   1 
ATOM 4728 C CB  . ALA C 3 22  ? 105.480 92.978  131.625 1.00 98.26  ? 22  ALA C CB  1 
ATOM 4729 N N   . ASN C 3 23  ? 107.331 94.732  129.677 1.00 93.64  ? 23  ASN C N   1 
ATOM 4730 C CA  . ASN C 3 23  ? 108.166 95.890  129.373 1.00 91.11  ? 23  ASN C CA  1 
ATOM 4731 C C   . ASN C 3 23  ? 107.575 96.719  128.244 1.00 91.07  ? 23  ASN C C   1 
ATOM 4732 O O   . ASN C 3 23  ? 107.578 97.952  128.309 1.00 91.70  ? 23  ASN C O   1 
ATOM 4733 C CB  . ASN C 3 23  ? 109.575 95.436  128.999 1.00 89.25  ? 23  ASN C CB  1 
ATOM 4734 C CG  . ASN C 3 23  ? 110.615 96.511  129.224 1.00 86.83  ? 23  ASN C CG  1 
ATOM 4735 O OD1 . ASN C 3 23  ? 111.701 96.251  129.738 1.00 88.17  ? 23  ASN C OD1 1 
ATOM 4736 N ND2 . ASN C 3 23  ? 110.273 97.735  128.871 1.00 87.74  ? 23  ASN C ND2 1 
ATOM 4737 N N   . LYS C 3 24  ? 107.083 96.058  127.195 1.00 94.17  ? 24  LYS C N   1 
ATOM 4738 C CA  . LYS C 3 24  ? 106.490 96.774  126.069 1.00 95.45  ? 24  LYS C CA  1 
ATOM 4739 C C   . LYS C 3 24  ? 105.241 97.536  126.495 1.00 89.79  ? 24  LYS C C   1 
ATOM 4740 O O   . LYS C 3 24  ? 105.061 98.702  126.120 1.00 91.98  ? 24  LYS C O   1 
ATOM 4741 C CB  . LYS C 3 24  ? 106.166 95.796  124.940 1.00 100.24 ? 24  LYS C CB  1 
ATOM 4742 C CG  . LYS C 3 24  ? 105.565 96.445  123.704 1.00 103.56 ? 24  LYS C CG  1 
ATOM 4743 C CD  . LYS C 3 24  ? 106.515 97.467  123.100 1.00 102.78 ? 24  LYS C CD  1 
ATOM 4744 C CE  . LYS C 3 24  ? 106.071 97.878  121.705 1.00 100.42 ? 24  LYS C CE  1 
ATOM 4745 N NZ  . LYS C 3 24  ? 104.742 98.550  121.719 1.00 98.40  ? 24  LYS C NZ  1 
ATOM 4746 N N   . LYS C 3 25  ? 104.387 96.904  127.304 1.00 85.52  ? 25  LYS C N   1 
ATOM 4747 C CA  . LYS C 3 25  ? 103.180 97.578  127.781 1.00 87.91  ? 25  LYS C CA  1 
ATOM 4748 C C   . LYS C 3 25  ? 103.517 98.761  128.687 1.00 91.52  ? 25  LYS C C   1 
ATOM 4749 O O   . LYS C 3 25  ? 102.925 99.845  128.560 1.00 95.96  ? 25  LYS C O   1 
ATOM 4750 C CB  . LYS C 3 25  ? 102.282 96.581  128.510 1.00 90.76  ? 25  LYS C CB  1 
ATOM 4751 C CG  . LYS C 3 25  ? 100.948 97.152  128.946 1.00 91.48  ? 25  LYS C CG  1 
ATOM 4752 C CD  . LYS C 3 25  ? 99.902  96.058  129.083 1.00 97.41  ? 25  LYS C CD  1 
ATOM 4753 C CE  . LYS C 3 25  ? 100.263 95.083  130.192 1.00 104.68 ? 25  LYS C CE  1 
ATOM 4754 N NZ  . LYS C 3 25  ? 100.504 95.778  131.487 1.00 104.38 ? 25  LYS C NZ  1 
ATOM 4755 N N   . ILE C 3 26  ? 104.489 98.579  129.587 1.00 89.55  ? 26  ILE C N   1 
ATOM 4756 C CA  . ILE C 3 26  ? 104.859 99.636  130.522 1.00 87.82  ? 26  ILE C CA  1 
ATOM 4757 C C   . ILE C 3 26  ? 105.514 100.800 129.786 1.00 88.14  ? 26  ILE C C   1 
ATOM 4758 O O   . ILE C 3 26  ? 105.237 101.970 130.078 1.00 89.18  ? 26  ILE C O   1 
ATOM 4759 C CB  . ILE C 3 26  ? 105.762 99.054  131.627 1.00 88.38  ? 26  ILE C CB  1 
ATOM 4760 C CG1 . ILE C 3 26  ? 104.921 98.317  132.674 1.00 92.46  ? 26  ILE C CG1 1 
ATOM 4761 C CG2 . ILE C 3 26  ? 106.593 100.132 132.308 1.00 88.22  ? 26  ILE C CG2 1 
ATOM 4762 C CD1 . ILE C 3 26  ? 103.682 99.067  133.132 1.00 90.02  ? 26  ILE C CD1 1 
ATOM 4763 N N   . GLU C 3 27  ? 106.357 100.504 128.793 1.00 90.43  ? 27  GLU C N   1 
ATOM 4764 C CA  . GLU C 3 27  ? 106.995 101.560 128.015 1.00 88.00  ? 27  GLU C CA  1 
ATOM 4765 C C   . GLU C 3 27  ? 105.987 102.296 127.142 1.00 83.37  ? 27  GLU C C   1 
ATOM 4766 O O   . GLU C 3 27  ? 106.121 103.505 126.923 1.00 84.47  ? 27  GLU C O   1 
ATOM 4767 C CB  . GLU C 3 27  ? 108.121 100.977 127.163 1.00 92.31  ? 27  GLU C CB  1 
ATOM 4768 C CG  . GLU C 3 27  ? 109.509 101.454 127.559 1.00 97.32  ? 27  GLU C CG  1 
ATOM 4769 C CD  . GLU C 3 27  ? 109.667 102.958 127.445 1.00 104.55 ? 27  GLU C CD  1 
ATOM 4770 O OE1 . GLU C 3 27  ? 109.198 103.535 126.441 1.00 103.71 ? 27  GLU C OE1 1 
ATOM 4771 O OE2 . GLU C 3 27  ? 110.260 103.565 128.362 1.00 105.24 ? 27  GLU C OE2 1 
ATOM 4772 N N   . LYS C 3 28  ? 104.972 101.587 126.637 1.00 82.55  ? 28  LYS C N   1 
ATOM 4773 C CA  . LYS C 3 28  ? 103.903 102.252 125.899 1.00 84.33  ? 28  LYS C CA  1 
ATOM 4774 C C   . LYS C 3 28  ? 103.138 103.219 126.793 1.00 83.73  ? 28  LYS C C   1 
ATOM 4775 O O   . LYS C 3 28  ? 102.856 104.356 126.391 1.00 87.13  ? 28  LYS C O   1 
ATOM 4776 C CB  . LYS C 3 28  ? 102.961 101.210 125.296 1.00 90.27  ? 28  LYS C CB  1 
ATOM 4777 C CG  . LYS C 3 28  ? 101.596 101.746 124.892 1.00 95.29  ? 28  LYS C CG  1 
ATOM 4778 C CD  . LYS C 3 28  ? 100.955 100.875 123.823 1.00 100.31 ? 28  LYS C CD  1 
ATOM 4779 C CE  . LYS C 3 28  ? 101.632 101.063 122.476 1.00 103.64 ? 28  LYS C CE  1 
ATOM 4780 N NZ  . LYS C 3 28  ? 101.870 102.500 122.169 1.00 100.12 ? 28  LYS C NZ  1 
ATOM 4781 N N   . GLN C 3 29  ? 102.829 102.800 128.024 1.00 82.78  ? 29  GLN C N   1 
ATOM 4782 C CA  . GLN C 3 29  ? 102.138 103.698 128.951 1.00 84.02  ? 29  GLN C CA  1 
ATOM 4783 C C   . GLN C 3 29  ? 103.014 104.884 129.348 1.00 84.53  ? 29  GLN C C   1 
ATOM 4784 O O   . GLN C 3 29  ? 102.523 106.016 129.474 1.00 89.09  ? 29  GLN C O   1 
ATOM 4785 C CB  . GLN C 3 29  ? 101.683 102.926 130.190 1.00 83.98  ? 29  GLN C CB  1 
ATOM 4786 C CG  . GLN C 3 29  ? 100.876 103.728 131.219 1.00 86.96  ? 29  GLN C CG  1 
ATOM 4787 C CD  . GLN C 3 29  ? 99.426  104.000 130.826 1.00 91.52  ? 29  GLN C CD  1 
ATOM 4788 O OE1 . GLN C 3 29  ? 99.108  104.301 129.677 1.00 91.48  ? 29  GLN C OE1 1 
ATOM 4789 N NE2 . GLN C 3 29  ? 98.534  103.891 131.803 1.00 93.03  ? 29  GLN C NE2 1 
ATOM 4790 N N   . LEU C 3 30  ? 104.312 104.645 129.545 1.00 80.86  ? 30  LEU C N   1 
ATOM 4791 C CA  . LEU C 3 30  ? 105.229 105.721 129.903 1.00 79.28  ? 30  LEU C CA  1 
ATOM 4792 C C   . LEU C 3 30  ? 105.371 106.735 128.777 1.00 82.19  ? 30  LEU C C   1 
ATOM 4793 O O   . LEU C 3 30  ? 105.410 107.944 129.028 1.00 82.13  ? 30  LEU C O   1 
ATOM 4794 C CB  . LEU C 3 30  ? 106.592 105.145 130.271 1.00 77.16  ? 30  LEU C CB  1 
ATOM 4795 C CG  . LEU C 3 30  ? 106.875 104.872 131.745 1.00 77.62  ? 30  LEU C CG  1 
ATOM 4796 C CD1 . LEU C 3 30  ? 108.371 104.788 131.953 1.00 78.42  ? 30  LEU C CD1 1 
ATOM 4797 C CD2 . LEU C 3 30  ? 106.270 105.943 132.634 1.00 78.41  ? 30  LEU C CD2 1 
ATOM 4798 N N   . GLN C 3 31  ? 105.455 106.265 127.530 1.00 85.29  ? 31  GLN C N   1 
ATOM 4799 C CA  . GLN C 3 31  ? 105.494 107.184 126.399 1.00 81.82  ? 31  GLN C CA  1 
ATOM 4800 C C   . GLN C 3 31  ? 104.171 107.915 126.229 1.00 77.55  ? 31  GLN C C   1 
ATOM 4801 O O   . GLN C 3 31  ? 104.154 109.051 125.746 1.00 77.13  ? 31  GLN C O   1 
ATOM 4802 C CB  . GLN C 3 31  ? 105.852 106.430 125.119 1.00 86.84  ? 31  GLN C CB  1 
ATOM 4803 C CG  . GLN C 3 31  ? 107.261 106.694 124.617 1.00 92.48  ? 31  GLN C CG  1 
ATOM 4804 C CD  . GLN C 3 31  ? 107.315 107.807 123.589 1.00 96.90  ? 31  GLN C CD  1 
ATOM 4805 O OE1 . GLN C 3 31  ? 106.343 108.537 123.396 1.00 96.06  ? 31  GLN C OE1 1 
ATOM 4806 N NE2 . GLN C 3 31  ? 108.456 107.941 122.923 1.00 96.29  ? 31  GLN C NE2 1 
ATOM 4807 N N   . LYS C 3 32  ? 103.059 107.275 126.602 1.00 79.08  ? 32  LYS C N   1 
ATOM 4808 C CA  . LYS C 3 32  ? 101.771 107.959 126.583 1.00 78.84  ? 32  LYS C CA  1 
ATOM 4809 C C   . LYS C 3 32  ? 101.737 109.103 127.586 1.00 77.15  ? 32  LYS C C   1 
ATOM 4810 O O   . LYS C 3 32  ? 101.204 110.179 127.293 1.00 79.37  ? 32  LYS C O   1 
ATOM 4811 C CB  . LYS C 3 32  ? 100.646 106.968 126.869 1.00 81.47  ? 32  LYS C CB  1 
ATOM 4812 C CG  . LYS C 3 32  ? 99.318  107.332 126.230 1.00 83.53  ? 32  LYS C CG  1 
ATOM 4813 C CD  . LYS C 3 32  ? 99.081  106.540 124.958 1.00 85.73  ? 32  LYS C CD  1 
ATOM 4814 C CE  . LYS C 3 32  ? 97.611  106.541 124.573 1.00 88.95  ? 32  LYS C CE  1 
ATOM 4815 N NZ  . LYS C 3 32  ? 96.750  106.020 125.671 1.00 89.15  ? 32  LYS C NZ  1 
ATOM 4816 N N   . ASP C 3 33  ? 102.296 108.892 128.775 1.00 77.03  ? 33  ASP C N   1 
ATOM 4817 C CA  . ASP C 3 33  ? 102.245 109.930 129.799 1.00 81.81  ? 33  ASP C CA  1 
ATOM 4818 C C   . ASP C 3 33  ? 103.392 110.931 129.714 1.00 77.47  ? 33  ASP C C   1 
ATOM 4819 O O   . ASP C 3 33  ? 103.338 111.969 130.388 1.00 79.52  ? 33  ASP C O   1 
ATOM 4820 C CB  . ASP C 3 33  ? 102.222 109.307 131.196 1.00 91.69  ? 33  ASP C CB  1 
ATOM 4821 C CG  . ASP C 3 33  ? 101.248 110.008 132.122 1.00 101.55 ? 33  ASP C CG  1 
ATOM 4822 O OD1 . ASP C 3 33  ? 100.129 110.332 131.671 1.00 101.18 ? 33  ASP C OD1 1 
ATOM 4823 O OD2 . ASP C 3 33  ? 101.601 110.254 133.291 1.00 109.23 ? 33  ASP C OD2 1 
ATOM 4824 N N   . LYS C 3 34  ? 104.419 110.653 128.907 1.00 74.14  ? 34  LYS C N   1 
ATOM 4825 C CA  . LYS C 3 34  ? 105.515 111.604 128.740 1.00 71.72  ? 34  LYS C CA  1 
ATOM 4826 C C   . LYS C 3 34  ? 105.046 112.890 128.069 1.00 71.44  ? 34  LYS C C   1 
ATOM 4827 O O   . LYS C 3 34  ? 105.438 113.991 128.477 1.00 70.70  ? 34  LYS C O   1 
ATOM 4828 C CB  . LYS C 3 34  ? 106.645 110.957 127.941 1.00 75.43  ? 34  LYS C CB  1 
ATOM 4829 C CG  . LYS C 3 34  ? 107.697 111.926 127.429 1.00 77.10  ? 34  LYS C CG  1 
ATOM 4830 C CD  . LYS C 3 34  ? 108.806 111.199 126.686 1.00 85.10  ? 34  LYS C CD  1 
ATOM 4831 C CE  . LYS C 3 34  ? 109.507 110.193 127.583 1.00 85.10  ? 34  LYS C CE  1 
ATOM 4832 N NZ  . LYS C 3 34  ? 110.563 109.440 126.851 1.00 83.81  ? 34  LYS C NZ  1 
ATOM 4833 N N   . GLN C 3 35  ? 104.203 112.771 127.040 1.00 71.07  ? 35  GLN C N   1 
ATOM 4834 C CA  . GLN C 3 35  ? 103.639 113.954 126.400 1.00 66.82  ? 35  GLN C CA  1 
ATOM 4835 C C   . GLN C 3 35  ? 102.708 114.704 127.337 1.00 65.11  ? 35  GLN C C   1 
ATOM 4836 O O   . GLN C 3 35  ? 102.614 115.932 127.258 1.00 69.36  ? 35  GLN C O   1 
ATOM 4837 C CB  . GLN C 3 35  ? 102.891 113.563 125.123 1.00 68.51  ? 35  GLN C CB  1 
ATOM 4838 C CG  . GLN C 3 35  ? 103.736 113.145 123.896 1.00 80.68  ? 35  GLN C CG  1 
ATOM 4839 C CD  . GLN C 3 35  ? 105.162 113.701 123.835 1.00 88.15  ? 35  GLN C CD  1 
ATOM 4840 O OE1 . GLN C 3 35  ? 106.111 112.944 123.633 1.00 89.44  ? 35  GLN C OE1 1 
ATOM 4841 N NE2 . GLN C 3 35  ? 105.299 115.028 123.859 1.00 85.95  ? 35  GLN C NE2 1 
ATOM 4842 N N   . VAL C 3 36  ? 102.026 113.988 128.231 1.00 65.00  ? 36  VAL C N   1 
ATOM 4843 C CA  . VAL C 3 36  ? 101.160 114.640 129.206 1.00 66.84  ? 36  VAL C CA  1 
ATOM 4844 C C   . VAL C 3 36  ? 101.990 115.438 130.203 1.00 63.24  ? 36  VAL C C   1 
ATOM 4845 O O   . VAL C 3 36  ? 101.611 116.548 130.597 1.00 64.14  ? 36  VAL C O   1 
ATOM 4846 C CB  . VAL C 3 36  ? 100.273 113.594 129.906 1.00 73.09  ? 36  VAL C CB  1 
ATOM 4847 C CG1 . VAL C 3 36  ? 99.314  114.261 130.882 1.00 75.50  ? 36  VAL C CG1 1 
ATOM 4848 C CG2 . VAL C 3 36  ? 99.510  112.775 128.877 1.00 71.80  ? 36  VAL C CG2 1 
ATOM 4849 N N   . TYR C 3 37  ? 103.135 114.896 130.618 1.00 60.13  ? 37  TYR C N   1 
ATOM 4850 C CA  . TYR C 3 37  ? 103.994 115.622 131.549 1.00 57.18  ? 37  TYR C CA  1 
ATOM 4851 C C   . TYR C 3 37  ? 104.641 116.828 130.882 1.00 60.16  ? 37  TYR C C   1 
ATOM 4852 O O   . TYR C 3 37  ? 104.651 117.928 131.445 1.00 64.47  ? 37  TYR C O   1 
ATOM 4853 C CB  . TYR C 3 37  ? 105.065 114.698 132.123 1.00 62.91  ? 37  TYR C CB  1 
ATOM 4854 C CG  . TYR C 3 37  ? 106.013 115.398 133.072 1.00 60.30  ? 37  TYR C CG  1 
ATOM 4855 C CD1 . TYR C 3 37  ? 105.645 115.649 134.383 1.00 60.16  ? 37  TYR C CD1 1 
ATOM 4856 C CD2 . TYR C 3 37  ? 107.274 115.802 132.658 1.00 58.43  ? 37  TYR C CD2 1 
ATOM 4857 C CE1 . TYR C 3 37  ? 106.502 116.284 135.252 1.00 60.23  ? 37  TYR C CE1 1 
ATOM 4858 C CE2 . TYR C 3 37  ? 108.134 116.442 133.518 1.00 59.13  ? 37  TYR C CE2 1 
ATOM 4859 C CZ  . TYR C 3 37  ? 107.744 116.677 134.814 1.00 60.87  ? 37  TYR C CZ  1 
ATOM 4860 O OH  . TYR C 3 37  ? 108.603 117.313 135.679 1.00 66.49  ? 37  TYR C OH  1 
ATOM 4861 N N   . ARG C 3 38  ? 105.200 116.643 129.688 1.00 60.69  ? 38  ARG C N   1 
ATOM 4862 C CA  . ARG C 3 38  ? 105.912 117.732 129.033 1.00 59.30  ? 38  ARG C CA  1 
ATOM 4863 C C   . ARG C 3 38  ? 104.980 118.762 128.413 1.00 61.40  ? 38  ARG C C   1 
ATOM 4864 O O   . ARG C 3 38  ? 105.424 119.872 128.105 1.00 60.96  ? 38  ARG C O   1 
ATOM 4865 C CB  . ARG C 3 38  ? 106.857 117.178 127.968 1.00 60.07  ? 38  ARG C CB  1 
ATOM 4866 C CG  . ARG C 3 38  ? 108.283 117.010 128.452 1.00 63.70  ? 38  ARG C CG  1 
ATOM 4867 C CD  . ARG C 3 38  ? 109.229 116.702 127.309 1.00 70.53  ? 38  ARG C CD  1 
ATOM 4868 N NE  . ARG C 3 38  ? 108.726 115.617 126.476 1.00 76.25  ? 38  ARG C NE  1 
ATOM 4869 C CZ  . ARG C 3 38  ? 108.825 115.576 125.155 1.00 81.54  ? 38  ARG C CZ  1 
ATOM 4870 N NH1 . ARG C 3 38  ? 109.440 116.530 124.478 1.00 82.95  ? 38  ARG C NH1 1 
ATOM 4871 N NH2 . ARG C 3 38  ? 108.303 114.545 124.498 1.00 82.46  ? 38  ARG C NH2 1 
ATOM 4872 N N   . ALA C 3 39  ? 103.705 118.430 128.226 1.00 63.44  ? 39  ALA C N   1 
ATOM 4873 C CA  . ALA C 3 39  ? 102.751 119.388 127.693 1.00 59.31  ? 39  ALA C CA  1 
ATOM 4874 C C   . ALA C 3 39  ? 102.249 120.365 128.742 1.00 62.22  ? 39  ALA C C   1 
ATOM 4875 O O   . ALA C 3 39  ? 101.625 121.366 128.379 1.00 69.92  ? 39  ALA C O   1 
ATOM 4876 C CB  . ALA C 3 39  ? 101.563 118.656 127.065 1.00 59.52  ? 39  ALA C CB  1 
ATOM 4877 N N   . THR C 3 40  ? 102.495 120.102 130.018 1.00 61.21  ? 40  THR C N   1 
ATOM 4878 C CA  . THR C 3 40  ? 102.065 120.990 131.084 1.00 64.71  ? 40  THR C CA  1 
ATOM 4879 C C   . THR C 3 40  ? 103.240 121.800 131.613 1.00 65.44  ? 40  THR C C   1 
ATOM 4880 O O   . THR C 3 40  ? 104.409 121.465 131.405 1.00 65.51  ? 40  THR C O   1 
ATOM 4881 C CB  . THR C 3 40  ? 101.394 120.204 132.218 1.00 65.63  ? 40  THR C CB  1 
ATOM 4882 O OG1 . THR C 3 40  ? 100.474 121.056 132.911 1.00 70.86  ? 40  THR C OG1 1 
ATOM 4883 C CG2 . THR C 3 40  ? 102.416 119.655 133.207 1.00 67.68  ? 40  THR C CG2 1 
ATOM 4884 N N   . HIS C 3 41  ? 102.909 122.903 132.271 1.00 65.39  ? 41  HIS C N   1 
ATOM 4885 C CA  . HIS C 3 41  ? 103.887 123.778 132.893 1.00 64.70  ? 41  HIS C CA  1 
ATOM 4886 C C   . HIS C 3 41  ? 103.529 123.940 134.359 1.00 63.84  ? 41  HIS C C   1 
ATOM 4887 O O   . HIS C 3 41  ? 102.361 124.137 134.704 1.00 68.31  ? 41  HIS C O   1 
ATOM 4888 C CB  . HIS C 3 41  ? 103.934 125.138 132.210 1.00 64.47  ? 41  HIS C CB  1 
ATOM 4889 C CG  . HIS C 3 41  ? 104.024 125.063 130.719 1.00 65.81  ? 41  HIS C CG  1 
ATOM 4890 N ND1 . HIS C 3 41  ? 105.221 125.140 130.043 1.00 66.01  ? 41  HIS C ND1 1 
ATOM 4891 C CD2 . HIS C 3 41  ? 103.065 124.933 129.774 1.00 68.02  ? 41  HIS C CD2 1 
ATOM 4892 C CE1 . HIS C 3 41  ? 104.996 125.053 128.744 1.00 73.12  ? 41  HIS C CE1 1 
ATOM 4893 N NE2 . HIS C 3 41  ? 103.696 124.927 128.554 1.00 73.62  ? 41  HIS C NE2 1 
ATOM 4894 N N   . ARG C 3 42  ? 104.537 123.857 135.215 1.00 59.94  ? 42  ARG C N   1 
ATOM 4895 C CA  . ARG C 3 42  ? 104.345 123.806 136.652 1.00 61.20  ? 42  ARG C CA  1 
ATOM 4896 C C   . ARG C 3 42  ? 104.698 125.146 137.278 1.00 62.39  ? 42  ARG C C   1 
ATOM 4897 O O   . ARG C 3 42  ? 105.746 125.726 136.981 1.00 66.94  ? 42  ARG C O   1 
ATOM 4898 C CB  . ARG C 3 42  ? 105.193 122.691 137.264 1.00 63.45  ? 42  ARG C CB  1 
ATOM 4899 C CG  . ARG C 3 42  ? 104.538 121.326 137.205 1.00 63.56  ? 42  ARG C CG  1 
ATOM 4900 C CD  . ARG C 3 42  ? 105.549 120.220 137.021 1.00 58.94  ? 42  ARG C CD  1 
ATOM 4901 N NE  . ARG C 3 42  ? 105.751 119.911 135.613 1.00 58.45  ? 42  ARG C NE  1 
ATOM 4902 C CZ  . ARG C 3 42  ? 106.859 120.180 134.939 1.00 63.46  ? 42  ARG C CZ  1 
ATOM 4903 N NH1 . ARG C 3 42  ? 107.894 120.767 135.517 1.00 65.50  ? 42  ARG C NH1 1 
ATOM 4904 N NH2 . ARG C 3 42  ? 106.932 119.853 133.652 1.00 64.02  ? 42  ARG C NH2 1 
ATOM 4905 N N   . LEU C 3 43  ? 103.815 125.631 138.142 1.00 59.68  ? 43  LEU C N   1 
ATOM 4906 C CA  . LEU C 3 43  ? 104.000 126.887 138.846 1.00 58.48  ? 43  LEU C CA  1 
ATOM 4907 C C   . LEU C 3 43  ? 103.860 126.652 140.342 1.00 64.84  ? 43  LEU C C   1 
ATOM 4908 O O   . LEU C 3 43  ? 103.016 125.865 140.778 1.00 71.48  ? 43  LEU C O   1 
ATOM 4909 C CB  . LEU C 3 43  ? 102.988 127.932 138.386 1.00 62.74  ? 43  LEU C CB  1 
ATOM 4910 C CG  . LEU C 3 43  ? 103.088 128.385 136.931 1.00 67.59  ? 43  LEU C CG  1 
ATOM 4911 C CD1 . LEU C 3 43  ? 101.754 128.912 136.444 1.00 67.58  ? 43  LEU C CD1 1 
ATOM 4912 C CD2 . LEU C 3 43  ? 104.165 129.441 136.775 1.00 68.38  ? 43  LEU C CD2 1 
ATOM 4913 N N   . LEU C 3 44  ? 104.695 127.329 141.123 1.00 60.32  ? 44  LEU C N   1 
ATOM 4914 C CA  . LEU C 3 44  ? 104.620 127.295 142.576 1.00 57.28  ? 44  LEU C CA  1 
ATOM 4915 C C   . LEU C 3 44  ? 104.138 128.647 143.080 1.00 56.98  ? 44  LEU C C   1 
ATOM 4916 O O   . LEU C 3 44  ? 104.648 129.688 142.656 1.00 64.25  ? 44  LEU C O   1 
ATOM 4917 C CB  . LEU C 3 44  ? 105.977 126.960 143.192 1.00 59.70  ? 44  LEU C CB  1 
ATOM 4918 C CG  . LEU C 3 44  ? 106.062 127.044 144.717 1.00 65.00  ? 44  LEU C CG  1 
ATOM 4919 C CD1 . LEU C 3 44  ? 105.167 126.007 145.361 1.00 65.93  ? 44  LEU C CD1 1 
ATOM 4920 C CD2 . LEU C 3 44  ? 107.494 126.886 145.194 1.00 69.71  ? 44  LEU C CD2 1 
ATOM 4921 N N   . LEU C 3 45  ? 103.162 128.628 143.977 1.00 57.69  ? 45  LEU C N   1 
ATOM 4922 C CA  . LEU C 3 45  ? 102.617 129.841 144.567 1.00 59.91  ? 45  LEU C CA  1 
ATOM 4923 C C   . LEU C 3 45  ? 103.168 130.005 145.976 1.00 65.11  ? 45  LEU C C   1 
ATOM 4924 O O   . LEU C 3 45  ? 103.083 129.083 146.793 1.00 73.86  ? 45  LEU C O   1 
ATOM 4925 C CB  . LEU C 3 45  ? 101.093 129.792 144.592 1.00 62.90  ? 45  LEU C CB  1 
ATOM 4926 C CG  . LEU C 3 45  ? 100.386 131.133 144.737 1.00 66.81  ? 45  LEU C CG  1 
ATOM 4927 C CD1 . LEU C 3 45  ? 99.288  131.256 143.700 1.00 71.35  ? 45  LEU C CD1 1 
ATOM 4928 C CD2 . LEU C 3 45  ? 99.824  131.285 146.133 1.00 77.06  ? 45  LEU C CD2 1 
ATOM 4929 N N   . LEU C 3 46  ? 103.727 131.177 146.257 1.00 59.89  ? 46  LEU C N   1 
ATOM 4930 C CA  . LEU C 3 46  ? 104.402 131.437 147.516 1.00 60.72  ? 46  LEU C CA  1 
ATOM 4931 C C   . LEU C 3 46  ? 103.923 132.760 148.094 1.00 65.04  ? 46  LEU C C   1 
ATOM 4932 O O   . LEU C 3 46  ? 103.458 133.646 147.373 1.00 70.47  ? 46  LEU C O   1 
ATOM 4933 C CB  . LEU C 3 46  ? 105.920 131.470 147.335 1.00 59.35  ? 46  LEU C CB  1 
ATOM 4934 C CG  . LEU C 3 46  ? 106.709 130.254 147.809 1.00 66.11  ? 46  LEU C CG  1 
ATOM 4935 C CD1 . LEU C 3 46  ? 108.192 130.553 147.745 1.00 63.78  ? 46  LEU C CD1 1 
ATOM 4936 C CD2 . LEU C 3 46  ? 106.300 129.857 149.216 1.00 70.47  ? 46  LEU C CD2 1 
ATOM 4937 N N   . GLY C 3 47  ? 104.041 132.882 149.410 1.00 63.61  ? 47  GLY C N   1 
ATOM 4938 C CA  . GLY C 3 47  ? 103.640 134.093 150.101 1.00 59.29  ? 47  GLY C CA  1 
ATOM 4939 C C   . GLY C 3 47  ? 104.816 134.913 150.592 1.00 58.58  ? 47  GLY C C   1 
ATOM 4940 O O   . GLY C 3 47  ? 104.724 135.602 151.607 1.00 61.05  ? 47  GLY C O   1 
ATOM 4941 N N   . SER C 3 51  ? 99.176  137.143 152.927 1.00 101.27 ? 51  SER C N   1 
ATOM 4942 C CA  . SER C 3 51  ? 99.749  137.964 151.867 1.00 99.56  ? 51  SER C CA  1 
ATOM 4943 C C   . SER C 3 51  ? 98.797  138.080 150.682 1.00 98.82  ? 51  SER C C   1 
ATOM 4944 O O   . SER C 3 51  ? 99.205  138.445 149.582 1.00 93.46  ? 51  SER C O   1 
ATOM 4945 C CB  . SER C 3 51  ? 101.089 137.388 151.405 1.00 90.59  ? 51  SER C CB  1 
ATOM 4946 O OG  . SER C 3 51  ? 100.916 136.129 150.778 1.00 91.02  ? 51  SER C OG  1 
ATOM 4947 N N   . GLY C 3 52  ? 97.526  137.765 150.914 1.00 100.92 ? 52  GLY C N   1 
ATOM 4948 C CA  . GLY C 3 52  ? 96.525  137.846 149.872 1.00 106.38 ? 52  GLY C CA  1 
ATOM 4949 C C   . GLY C 3 52  ? 96.545  136.724 148.860 1.00 110.83 ? 52  GLY C C   1 
ATOM 4950 O O   . GLY C 3 52  ? 96.006  136.898 147.761 1.00 113.64 ? 52  GLY C O   1 
ATOM 4951 N N   . LYS C 3 53  ? 97.152  135.579 149.188 1.00 109.83 ? 53  LYS C N   1 
ATOM 4952 C CA  . LYS C 3 53  ? 97.176  134.459 148.252 1.00 107.93 ? 53  LYS C CA  1 
ATOM 4953 C C   . LYS C 3 53  ? 95.800  133.825 148.094 1.00 110.55 ? 53  LYS C C   1 
ATOM 4954 O O   . LYS C 3 53  ? 95.484  133.291 147.024 1.00 110.42 ? 53  LYS C O   1 
ATOM 4955 C CB  . LYS C 3 53  ? 98.191  133.411 148.706 1.00 102.36 ? 53  LYS C CB  1 
ATOM 4956 C CG  . LYS C 3 53  ? 98.201  133.156 150.203 1.00 103.59 ? 53  LYS C CG  1 
ATOM 4957 C CD  . LYS C 3 53  ? 99.044  131.938 150.554 1.00 97.74  ? 53  LYS C CD  1 
ATOM 4958 C CE  . LYS C 3 53  ? 100.438 132.025 149.953 1.00 87.71  ? 53  LYS C CE  1 
ATOM 4959 N NZ  . LYS C 3 53  ? 101.216 130.775 150.171 1.00 82.90  ? 53  LYS C NZ  1 
ATOM 4960 N N   . ASN C 3 54  ? 94.979  133.869 149.146 1.00 109.32 ? 54  ASN C N   1 
ATOM 4961 C CA  . ASN C 3 54  ? 93.633  133.313 149.065 1.00 112.29 ? 54  ASN C CA  1 
ATOM 4962 C C   . ASN C 3 54  ? 92.773  134.085 148.072 1.00 117.15 ? 54  ASN C C   1 
ATOM 4963 O O   . ASN C 3 54  ? 92.008  133.486 147.309 1.00 119.52 ? 54  ASN C O   1 
ATOM 4964 C CB  . ASN C 3 54  ? 92.984  133.309 150.449 1.00 117.64 ? 54  ASN C CB  1 
ATOM 4965 C CG  . ASN C 3 54  ? 91.516  132.932 150.403 1.00 120.87 ? 54  ASN C CG  1 
ATOM 4966 O OD1 . ASN C 3 54  ? 91.155  131.855 149.927 1.00 121.25 ? 54  ASN C OD1 1 
ATOM 4967 N ND2 . ASN C 3 54  ? 90.661  133.820 150.896 1.00 116.84 ? 54  ASN C ND2 1 
ATOM 4968 N N   . THR C 3 55  ? 92.899  135.415 148.056 1.00 119.18 ? 55  THR C N   1 
ATOM 4969 C CA  . THR C 3 55  ? 92.107  136.227 147.136 1.00 120.50 ? 55  THR C CA  1 
ATOM 4970 C C   . THR C 3 55  ? 92.506  135.982 145.684 1.00 116.95 ? 55  THR C C   1 
ATOM 4971 O O   . THR C 3 55  ? 91.637  135.850 144.812 1.00 120.61 ? 55  THR C O   1 
ATOM 4972 C CB  . THR C 3 55  ? 92.249  137.708 147.485 1.00 120.49 ? 55  THR C CB  1 
ATOM 4973 O OG1 . THR C 3 55  ? 93.552  138.169 147.107 1.00 116.26 ? 55  THR C OG1 1 
ATOM 4974 C CG2 . THR C 3 55  ? 92.054  137.923 148.979 1.00 116.21 ? 55  THR C CG2 1 
ATOM 4975 N N   . ILE C 3 56  ? 93.808  135.900 145.405 1.00 111.48 ? 56  ILE C N   1 
ATOM 4976 C CA  . ILE C 3 56  ? 94.225  135.684 144.025 1.00 108.67 ? 56  ILE C CA  1 
ATOM 4977 C C   . ILE C 3 56  ? 93.924  134.251 143.583 1.00 114.07 ? 56  ILE C C   1 
ATOM 4978 O O   . ILE C 3 56  ? 93.562  134.028 142.423 1.00 117.09 ? 56  ILE C O   1 
ATOM 4979 C CB  . ILE C 3 56  ? 95.706  136.071 143.828 1.00 103.23 ? 56  ILE C CB  1 
ATOM 4980 C CG1 . ILE C 3 56  ? 96.117  135.950 142.358 1.00 98.95  ? 56  ILE C CG1 1 
ATOM 4981 C CG2 . ILE C 3 56  ? 96.631  135.240 144.687 1.00 104.44 ? 56  ILE C CG2 1 
ATOM 4982 C CD1 . ILE C 3 56  ? 97.541  136.371 142.082 1.00 90.32  ? 56  ILE C CD1 1 
ATOM 4983 N N   . VAL C 3 57  ? 93.991  133.264 144.486 1.00 116.58 ? 57  VAL C N   1 
ATOM 4984 C CA  . VAL C 3 57  ? 93.646  131.903 144.074 1.00 117.61 ? 57  VAL C CA  1 
ATOM 4985 C C   . VAL C 3 57  ? 92.132  131.757 143.923 1.00 122.59 ? 57  VAL C C   1 
ATOM 4986 O O   . VAL C 3 57  ? 91.651  130.953 143.115 1.00 123.02 ? 57  VAL C O   1 
ATOM 4987 C CB  . VAL C 3 57  ? 94.252  130.857 145.036 1.00 109.90 ? 57  VAL C CB  1 
ATOM 4988 C CG1 . VAL C 3 57  ? 93.477  130.741 146.337 1.00 109.88 ? 57  VAL C CG1 1 
ATOM 4989 C CG2 . VAL C 3 57  ? 94.353  129.505 144.351 1.00 104.00 ? 57  VAL C CG2 1 
ATOM 4990 N N   . LYS C 3 58  ? 91.355  132.570 144.649 1.00 123.93 ? 58  LYS C N   1 
ATOM 4991 C CA  . LYS C 3 58  ? 89.915  132.605 144.419 1.00 122.83 ? 58  LYS C CA  1 
ATOM 4992 C C   . LYS C 3 58  ? 89.585  133.255 143.083 1.00 125.27 ? 58  LYS C C   1 
ATOM 4993 O O   . LYS C 3 58  ? 88.653  132.820 142.397 1.00 129.09 ? 58  LYS C O   1 
ATOM 4994 C CB  . LYS C 3 58  ? 89.217  133.345 145.559 1.00 121.00 ? 58  LYS C CB  1 
ATOM 4995 N N   . GLN C 3 59  ? 90.337  134.292 142.703 1.00 123.48 ? 59  GLN C N   1 
ATOM 4996 C CA  . GLN C 3 59  ? 90.196  134.869 141.370 1.00 122.52 ? 59  GLN C CA  1 
ATOM 4997 C C   . GLN C 3 59  ? 90.574  133.856 140.294 1.00 124.72 ? 59  GLN C C   1 
ATOM 4998 O O   . GLN C 3 59  ? 89.944  133.802 139.230 1.00 125.86 ? 59  GLN C O   1 
ATOM 4999 C CB  . GLN C 3 59  ? 91.052  136.134 141.258 1.00 120.41 ? 59  GLN C CB  1 
ATOM 5000 C CG  . GLN C 3 59  ? 91.125  136.749 139.865 1.00 116.37 ? 59  GLN C CG  1 
ATOM 5001 C CD  . GLN C 3 59  ? 92.408  136.400 139.134 1.00 109.35 ? 59  GLN C CD  1 
ATOM 5002 O OE1 . GLN C 3 59  ? 93.281  135.723 139.677 1.00 110.21 ? 59  GLN C OE1 1 
ATOM 5003 N NE2 . GLN C 3 59  ? 92.527  136.858 137.893 1.00 99.45  ? 59  GLN C NE2 1 
ATOM 5004 N N   . MET C 3 60  ? 91.599  133.041 140.563 1.00 122.04 ? 60  MET C N   1 
ATOM 5005 C CA  . MET C 3 60  ? 91.969  131.966 139.646 1.00 121.67 ? 60  MET C CA  1 
ATOM 5006 C C   . MET C 3 60  ? 90.848  130.943 139.507 1.00 127.57 ? 60  MET C C   1 
ATOM 5007 O O   . MET C 3 60  ? 90.542  130.494 138.396 1.00 130.81 ? 60  MET C O   1 
ATOM 5008 C CB  . MET C 3 60  ? 93.249  131.276 140.124 1.00 116.60 ? 60  MET C CB  1 
ATOM 5009 C CG  . MET C 3 60  ? 94.534  132.003 139.773 1.00 114.72 ? 60  MET C CG  1 
ATOM 5010 S SD  . MET C 3 60  ? 95.757  132.116 141.092 1.00 123.64 ? 60  MET C SD  1 
ATOM 5011 C CE  . MET C 3 60  ? 97.065  133.012 140.259 1.00 101.91 ? 60  MET C CE  1 
ATOM 5012 N N   . ARG C 3 61  ? 90.228  130.563 140.627 1.00 126.40 ? 61  ARG C N   1 
ATOM 5013 C CA  . ARG C 3 61  ? 89.150  129.579 140.590 1.00 130.03 ? 61  ARG C CA  1 
ATOM 5014 C C   . ARG C 3 61  ? 87.914  130.135 139.892 1.00 135.90 ? 61  ARG C C   1 
ATOM 5015 O O   . ARG C 3 61  ? 87.186  129.395 139.220 1.00 137.17 ? 61  ARG C O   1 
ATOM 5016 C CB  . ARG C 3 61  ? 88.808  129.125 142.009 1.00 126.15 ? 61  ARG C CB  1 
ATOM 5017 N N   . ILE C 3 62  ? 87.654  131.434 140.054 1.00 136.46 ? 62  ILE C N   1 
ATOM 5018 C CA  . ILE C 3 62  ? 86.542  132.068 139.351 1.00 136.33 ? 62  ILE C CA  1 
ATOM 5019 C C   . ILE C 3 62  ? 86.827  132.146 137.857 1.00 140.37 ? 62  ILE C C   1 
ATOM 5020 O O   . ILE C 3 62  ? 85.924  131.981 137.027 1.00 142.87 ? 62  ILE C O   1 
ATOM 5021 C CB  . ILE C 3 62  ? 86.256  133.459 139.946 1.00 130.79 ? 62  ILE C CB  1 
ATOM 5022 N N   . LEU C 3 63  ? 88.085  132.408 137.489 1.00 138.03 ? 63  LEU C N   1 
ATOM 5023 C CA  . LEU C 3 63  ? 88.443  132.486 136.076 1.00 137.01 ? 63  LEU C CA  1 
ATOM 5024 C C   . LEU C 3 63  ? 88.425  131.110 135.421 1.00 139.75 ? 63  LEU C C   1 
ATOM 5025 O O   . LEU C 3 63  ? 88.034  130.974 134.255 1.00 140.37 ? 63  LEU C O   1 
ATOM 5026 C CB  . LEU C 3 63  ? 89.817  133.137 135.919 1.00 128.42 ? 63  LEU C CB  1 
ATOM 5027 N N   . HIS C 3 64  ? 88.845  130.081 136.150 1.00 141.15 ? 64  HIS C N   1 
ATOM 5028 C CA  . HIS C 3 64  ? 88.870  128.725 135.614 1.00 140.75 ? 64  HIS C CA  1 
ATOM 5029 C C   . HIS C 3 64  ? 87.467  128.127 135.569 1.00 141.16 ? 64  HIS C C   1 
ATOM 5030 O O   . HIS C 3 64  ? 86.947  127.820 134.497 1.00 143.15 ? 64  HIS C O   1 
ATOM 5031 C CB  . HIS C 3 64  ? 89.795  127.836 136.447 1.00 131.30 ? 64  HIS C CB  1 
ATOM 5032 N N   . THR C 3 204 ? 93.235  118.716 155.983 1.00 111.64 ? 204 THR C N   1 
ATOM 5033 C CA  . THR C 3 204 ? 94.428  119.547 155.874 1.00 109.92 ? 204 THR C CA  1 
ATOM 5034 C C   . THR C 3 204 ? 95.489  118.874 155.010 1.00 102.38 ? 204 THR C C   1 
ATOM 5035 O O   . THR C 3 204 ? 96.486  118.363 155.520 1.00 98.46  ? 204 THR C O   1 
ATOM 5036 C CB  . THR C 3 204 ? 95.027  119.860 157.257 1.00 110.21 ? 204 THR C CB  1 
ATOM 5037 O OG1 . THR C 3 204 ? 95.366  118.636 157.921 1.00 111.09 ? 204 THR C OG1 1 
ATOM 5038 C CG2 . THR C 3 204 ? 94.030  120.633 158.106 1.00 110.62 ? 204 THR C CG2 1 
ATOM 5039 N N   . SER C 3 205 ? 95.262  118.873 153.700 1.00 100.76 ? 205 SER C N   1 
ATOM 5040 C CA  . SER C 3 205 ? 96.222  118.296 152.772 1.00 95.60  ? 205 SER C CA  1 
ATOM 5041 C C   . SER C 3 205 ? 97.471  119.164 152.687 1.00 91.97  ? 205 SER C C   1 
ATOM 5042 O O   . SER C 3 205 ? 97.428  120.378 152.904 1.00 91.85  ? 205 SER C O   1 
ATOM 5043 C CB  . SER C 3 205 ? 95.599  118.138 151.386 1.00 96.62  ? 205 SER C CB  1 
ATOM 5044 O OG  . SER C 3 205 ? 96.560  117.702 150.440 1.00 92.47  ? 205 SER C OG  1 
ATOM 5045 N N   . GLY C 3 206 ? 98.596  118.524 152.375 1.00 89.43  ? 206 GLY C N   1 
ATOM 5046 C CA  . GLY C 3 206 ? 99.851  119.253 152.311 1.00 88.53  ? 206 GLY C CA  1 
ATOM 5047 C C   . GLY C 3 206 ? 99.998  120.075 151.045 1.00 86.43  ? 206 GLY C C   1 
ATOM 5048 O O   . GLY C 3 206 ? 100.670 121.109 151.041 1.00 85.17  ? 206 GLY C O   1 
ATOM 5049 N N   . ILE C 3 207 ? 99.385  119.625 149.954 1.00 84.79  ? 207 ILE C N   1 
ATOM 5050 C CA  . ILE C 3 207 ? 99.504  120.275 148.656 1.00 80.27  ? 207 ILE C CA  1 
ATOM 5051 C C   . ILE C 3 207 ? 98.110  120.420 148.067 1.00 83.15  ? 207 ILE C C   1 
ATOM 5052 O O   . ILE C 3 207 ? 97.354  119.444 148.004 1.00 84.22  ? 207 ILE C O   1 
ATOM 5053 C CB  . ILE C 3 207 ? 100.431 119.481 147.714 1.00 78.23  ? 207 ILE C CB  1 
ATOM 5054 C CG1 . ILE C 3 207 ? 101.895 119.801 148.015 1.00 76.61  ? 207 ILE C CG1 1 
ATOM 5055 C CG2 . ILE C 3 207 ? 100.138 119.780 146.247 1.00 80.32  ? 207 ILE C CG2 1 
ATOM 5056 C CD1 . ILE C 3 207 ? 102.205 121.276 148.048 1.00 75.01  ? 207 ILE C CD1 1 
ATOM 5057 N N   . PHE C 3 208 ? 97.765  121.634 147.651 1.00 81.77  ? 208 PHE C N   1 
ATOM 5058 C CA  . PHE C 3 208 ? 96.475  121.897 147.038 1.00 82.46  ? 208 PHE C CA  1 
ATOM 5059 C C   . PHE C 3 208 ? 96.593  121.880 145.519 1.00 81.72  ? 208 PHE C C   1 
ATOM 5060 O O   . PHE C 3 208 ? 97.632  122.222 144.951 1.00 75.60  ? 208 PHE C O   1 
ATOM 5061 C CB  . PHE C 3 208 ? 95.922  123.236 147.519 1.00 80.72  ? 208 PHE C CB  1 
ATOM 5062 C CG  . PHE C 3 208 ? 95.680  123.285 148.998 1.00 83.64  ? 208 PHE C CG  1 
ATOM 5063 C CD1 . PHE C 3 208 ? 94.590  122.640 149.556 1.00 88.89  ? 208 PHE C CD1 1 
ATOM 5064 C CD2 . PHE C 3 208 ? 96.549  123.968 149.831 1.00 84.22  ? 208 PHE C CD2 1 
ATOM 5065 C CE1 . PHE C 3 208 ? 94.369  122.680 150.919 1.00 94.25  ? 208 PHE C CE1 1 
ATOM 5066 C CE2 . PHE C 3 208 ? 96.334  124.013 151.194 1.00 87.17  ? 208 PHE C CE2 1 
ATOM 5067 C CZ  . PHE C 3 208 ? 95.242  123.368 151.738 1.00 93.32  ? 208 PHE C CZ  1 
ATOM 5068 N N   . GLU C 3 209 ? 95.510  121.472 144.866 1.00 88.04  ? 209 GLU C N   1 
ATOM 5069 C CA  . GLU C 3 209 ? 95.500  121.200 143.435 1.00 90.66  ? 209 GLU C CA  1 
ATOM 5070 C C   . GLU C 3 209 ? 94.618  122.209 142.713 1.00 89.35  ? 209 GLU C C   1 
ATOM 5071 O O   . GLU C 3 209 ? 93.427  122.327 143.018 1.00 90.62  ? 209 GLU C O   1 
ATOM 5072 C CB  . GLU C 3 209 ? 94.991  119.780 143.168 1.00 96.73  ? 209 GLU C CB  1 
ATOM 5073 C CG  . GLU C 3 209 ? 96.068  118.709 143.170 1.00 97.19  ? 209 GLU C CG  1 
ATOM 5074 C CD  . GLU C 3 209 ? 96.806  118.622 141.852 1.00 98.62  ? 209 GLU C CD  1 
ATOM 5075 O OE1 . GLU C 3 209 ? 97.690  119.467 141.610 1.00 94.61  ? 209 GLU C OE1 1 
ATOM 5076 O OE2 . GLU C 3 209 ? 96.503  117.706 141.058 1.00 103.22 ? 209 GLU C OE2 1 
ATOM 5077 N N   . THR C 3 210 ? 95.204  122.937 141.760 1.00 83.77  ? 210 THR C N   1 
ATOM 5078 C CA  . THR C 3 210 ? 94.449  123.773 140.837 1.00 81.65  ? 210 THR C CA  1 
ATOM 5079 C C   . THR C 3 210 ? 94.842  123.420 139.408 1.00 78.86  ? 210 THR C C   1 
ATOM 5080 O O   . THR C 3 210 ? 95.966  122.990 139.142 1.00 76.33  ? 210 THR C O   1 
ATOM 5081 C CB  . THR C 3 210 ? 94.680  125.277 141.058 1.00 79.47  ? 210 THR C CB  1 
ATOM 5082 O OG1 . THR C 3 210 ? 95.833  125.689 140.320 1.00 80.97  ? 210 THR C OG1 1 
ATOM 5083 C CG2 . THR C 3 210 ? 94.877  125.616 142.532 1.00 77.98  ? 210 THR C CG2 1 
ATOM 5084 N N   . LYS C 3 211 ? 93.900  123.612 138.483 1.00 77.02  ? 211 LYS C N   1 
ATOM 5085 C CA  . LYS C 3 211 ? 94.130  123.359 137.066 1.00 71.29  ? 211 LYS C CA  1 
ATOM 5086 C C   . LYS C 3 211 ? 93.700  124.563 136.245 1.00 73.07  ? 211 LYS C C   1 
ATOM 5087 O O   . LYS C 3 211 ? 92.649  125.154 136.509 1.00 77.83  ? 211 LYS C O   1 
ATOM 5088 C CB  . LYS C 3 211 ? 93.369  122.110 136.583 1.00 73.63  ? 211 LYS C CB  1 
ATOM 5089 C CG  . LYS C 3 211 ? 93.612  120.761 137.314 1.00 82.22  ? 211 LYS C CG  1 
ATOM 5090 C CD  . LYS C 3 211 ? 95.060  120.280 137.578 1.00 81.04  ? 211 LYS C CD  1 
ATOM 5091 C CE  . LYS C 3 211 ? 96.061  120.522 136.444 1.00 79.00  ? 211 LYS C CE  1 
ATOM 5092 N NZ  . LYS C 3 211 ? 95.618  119.890 135.174 1.00 82.33  ? 211 LYS C NZ  1 
ATOM 5093 N N   . PHE C 3 212 ? 94.517  124.926 135.260 1.00 70.55  ? 212 PHE C N   1 
ATOM 5094 C CA  . PHE C 3 212 ? 94.209  125.976 134.298 1.00 69.81  ? 212 PHE C CA  1 
ATOM 5095 C C   . PHE C 3 212 ? 94.075  125.373 132.908 1.00 69.45  ? 212 PHE C C   1 
ATOM 5096 O O   . PHE C 3 212 ? 94.674  124.339 132.601 1.00 70.94  ? 212 PHE C O   1 
ATOM 5097 C CB  . PHE C 3 212 ? 95.288  127.073 134.243 1.00 73.03  ? 212 PHE C CB  1 
ATOM 5098 C CG  . PHE C 3 212 ? 95.497  127.852 135.524 1.00 76.46  ? 212 PHE C CG  1 
ATOM 5099 C CD1 . PHE C 3 212 ? 96.469  128.836 135.562 1.00 75.30  ? 212 PHE C CD1 1 
ATOM 5100 C CD2 . PHE C 3 212 ? 94.677  127.698 136.629 1.00 80.26  ? 212 PHE C CD2 1 
ATOM 5101 C CE1 . PHE C 3 212 ? 96.676  129.580 136.696 1.00 81.97  ? 212 PHE C CE1 1 
ATOM 5102 C CE2 . PHE C 3 212 ? 94.878  128.438 137.769 1.00 86.04  ? 212 PHE C CE2 1 
ATOM 5103 C CZ  . PHE C 3 212 ? 95.876  129.384 137.801 1.00 89.07  ? 212 PHE C CZ  1 
ATOM 5104 N N   . GLN C 3 213 ? 93.285  126.027 132.065 1.00 66.27  ? 213 GLN C N   1 
ATOM 5105 C CA  . GLN C 3 213 ? 93.150  125.627 130.670 1.00 66.81  ? 213 GLN C CA  1 
ATOM 5106 C C   . GLN C 3 213 ? 93.117  126.848 129.766 1.00 71.03  ? 213 GLN C C   1 
ATOM 5107 O O   . GLN C 3 213 ? 92.297  126.937 128.846 1.00 76.80  ? 213 GLN C O   1 
ATOM 5108 C CB  . GLN C 3 213 ? 91.905  124.769 130.456 1.00 72.30  ? 213 GLN C CB  1 
ATOM 5109 C CG  . GLN C 3 213 ? 92.093  123.671 129.424 1.00 73.03  ? 213 GLN C CG  1 
ATOM 5110 C CD  . GLN C 3 213 ? 93.421  122.960 129.570 1.00 71.76  ? 213 GLN C CD  1 
ATOM 5111 O OE1 . GLN C 3 213 ? 93.684  122.319 130.586 1.00 73.40  ? 213 GLN C OE1 1 
ATOM 5112 N NE2 . GLN C 3 213 ? 94.270  123.077 128.557 1.00 70.12  ? 213 GLN C NE2 1 
ATOM 5113 N N   . VAL C 3 214 ? 93.999  127.810 130.012 1.00 67.78  ? 214 VAL C N   1 
ATOM 5114 C CA  . VAL C 3 214 ? 93.998  129.046 129.238 1.00 63.68  ? 214 VAL C CA  1 
ATOM 5115 C C   . VAL C 3 214 ? 94.647  128.810 127.876 1.00 62.87  ? 214 VAL C C   1 
ATOM 5116 O O   . VAL C 3 214 ? 95.755  128.270 127.785 1.00 64.33  ? 214 VAL C O   1 
ATOM 5117 C CB  . VAL C 3 214 ? 94.670  130.190 130.016 1.00 62.97  ? 214 VAL C CB  1 
ATOM 5118 C CG1 . VAL C 3 214 ? 96.071  129.830 130.483 1.00 61.57  ? 214 VAL C CG1 1 
ATOM 5119 C CG2 . VAL C 3 214 ? 94.711  131.448 129.170 1.00 67.77  ? 214 VAL C CG2 1 
ATOM 5120 N N   . ASP C 3 215 ? 93.912  129.162 126.812 1.00 61.58  ? 215 ASP C N   1 
ATOM 5121 C CA  . ASP C 3 215 ? 94.391  129.154 125.424 1.00 66.37  ? 215 ASP C CA  1 
ATOM 5122 C C   . ASP C 3 215 ? 94.903  127.781 124.995 1.00 67.09  ? 215 ASP C C   1 
ATOM 5123 O O   . ASP C 3 215 ? 95.912  127.673 124.293 1.00 72.19  ? 215 ASP C O   1 
ATOM 5124 C CB  . ASP C 3 215 ? 95.461  130.225 125.206 1.00 74.92  ? 215 ASP C CB  1 
ATOM 5125 C CG  . ASP C 3 215 ? 94.886  131.626 125.202 1.00 80.38  ? 215 ASP C CG  1 
ATOM 5126 O OD1 . ASP C 3 215 ? 93.730  131.794 125.643 1.00 83.54  ? 215 ASP C OD1 1 
ATOM 5127 O OD2 . ASP C 3 215 ? 95.591  132.560 124.763 1.00 80.41  ? 215 ASP C OD2 1 
ATOM 5128 N N   . LYS C 3 216 ? 94.207  126.733 125.445 1.00 63.52  ? 216 LYS C N   1 
ATOM 5129 C CA  . LYS C 3 216 ? 94.538  125.328 125.172 1.00 63.38  ? 216 LYS C CA  1 
ATOM 5130 C C   . LYS C 3 216 ? 95.937  124.955 125.653 1.00 62.10  ? 216 LYS C C   1 
ATOM 5131 O O   . LYS C 3 216 ? 96.582  124.071 125.086 1.00 64.76  ? 216 LYS C O   1 
ATOM 5132 C CB  . LYS C 3 216 ? 94.370  124.977 123.690 1.00 65.07  ? 216 LYS C CB  1 
ATOM 5133 C CG  . LYS C 3 216 ? 93.028  124.349 123.350 1.00 66.55  ? 216 LYS C CG  1 
ATOM 5134 C CD  . LYS C 3 216 ? 92.969  122.879 123.751 1.00 71.52  ? 216 LYS C CD  1 
ATOM 5135 C CE  . LYS C 3 216 ? 94.188  122.107 123.262 1.00 74.25  ? 216 LYS C CE  1 
ATOM 5136 N NZ  . LYS C 3 216 ? 94.100  120.658 123.593 1.00 72.31  ? 216 LYS C NZ  1 
ATOM 5137 N N   . VAL C 3 217 ? 96.421  125.626 126.696 1.00 60.46  ? 217 VAL C N   1 
ATOM 5138 C CA  . VAL C 3 217 ? 97.630  125.231 127.407 1.00 60.60  ? 217 VAL C CA  1 
ATOM 5139 C C   . VAL C 3 217 ? 97.251  124.966 128.855 1.00 67.69  ? 217 VAL C C   1 
ATOM 5140 O O   . VAL C 3 217 ? 96.593  125.798 129.490 1.00 71.47  ? 217 VAL C O   1 
ATOM 5141 C CB  . VAL C 3 217 ? 98.735  126.298 127.324 1.00 60.92  ? 217 VAL C CB  1 
ATOM 5142 C CG1 . VAL C 3 217 ? 100.077 125.676 127.656 1.00 64.43  ? 217 VAL C CG1 1 
ATOM 5143 C CG2 . VAL C 3 217 ? 98.777  126.939 125.946 1.00 64.53  ? 217 VAL C CG2 1 
ATOM 5144 N N   . ASN C 3 218 ? 97.660  123.814 129.373 1.00 67.96  ? 218 ASN C N   1 
ATOM 5145 C CA  . ASN C 3 218 ? 97.319  123.403 130.728 1.00 70.27  ? 218 ASN C CA  1 
ATOM 5146 C C   . ASN C 3 218 ? 98.449  123.723 131.701 1.00 70.15  ? 218 ASN C C   1 
ATOM 5147 O O   . ASN C 3 218 ? 99.619  123.438 131.429 1.00 69.59  ? 218 ASN C O   1 
ATOM 5148 C CB  . ASN C 3 218 ? 96.936  121.919 130.762 1.00 71.39  ? 218 ASN C CB  1 
ATOM 5149 C CG  . ASN C 3 218 ? 97.853  121.038 129.925 1.00 73.51  ? 218 ASN C CG  1 
ATOM 5150 O OD1 . ASN C 3 218 ? 99.056  121.249 129.841 1.00 74.80  ? 218 ASN C OD1 1 
ATOM 5151 N ND2 . ASN C 3 218 ? 97.262  120.033 129.288 1.00 74.64  ? 218 ASN C ND2 1 
ATOM 5152 N N   . PHE C 3 219 ? 98.097  124.355 132.816 1.00 67.81  ? 219 PHE C N   1 
ATOM 5153 C CA  . PHE C 3 219 ? 99.060  124.803 133.809 1.00 64.69  ? 219 PHE C CA  1 
ATOM 5154 C C   . PHE C 3 219 ? 98.839  124.086 135.133 1.00 68.31  ? 219 PHE C C   1 
ATOM 5155 O O   . PHE C 3 219 ? 97.701  123.920 135.579 1.00 73.07  ? 219 PHE C O   1 
ATOM 5156 C CB  . PHE C 3 219 ? 98.961  126.314 134.028 1.00 65.92  ? 219 PHE C CB  1 
ATOM 5157 C CG  . PHE C 3 219 ? 99.606  127.131 132.949 1.00 67.44  ? 219 PHE C CG  1 
ATOM 5158 C CD1 . PHE C 3 219 ? 100.975 127.105 132.767 1.00 69.24  ? 219 PHE C CD1 1 
ATOM 5159 C CD2 . PHE C 3 219 ? 98.844  127.935 132.126 1.00 68.72  ? 219 PHE C CD2 1 
ATOM 5160 C CE1 . PHE C 3 219 ? 101.569 127.861 131.779 1.00 69.82  ? 219 PHE C CE1 1 
ATOM 5161 C CE2 . PHE C 3 219 ? 99.433  128.689 131.136 1.00 68.91  ? 219 PHE C CE2 1 
ATOM 5162 C CZ  . PHE C 3 219 ? 100.796 128.652 130.963 1.00 68.95  ? 219 PHE C CZ  1 
ATOM 5163 N N   . HIS C 3 220 ? 99.934  123.672 135.755 1.00 69.79  ? 220 HIS C N   1 
ATOM 5164 C CA  . HIS C 3 220 ? 99.939  123.192 137.129 1.00 71.02  ? 220 HIS C CA  1 
ATOM 5165 C C   . HIS C 3 220 ? 100.283 124.348 138.056 1.00 74.08  ? 220 HIS C C   1 
ATOM 5166 O O   . HIS C 3 220 ? 101.257 125.069 137.819 1.00 78.53  ? 220 HIS C O   1 
ATOM 5167 C CB  . HIS C 3 220 ? 100.961 122.073 137.318 1.00 71.29  ? 220 HIS C CB  1 
ATOM 5168 C CG  . HIS C 3 220 ? 100.391 120.695 137.214 1.00 75.38  ? 220 HIS C CG  1 
ATOM 5169 N ND1 . HIS C 3 220 ? 99.217  120.325 137.832 1.00 79.96  ? 220 HIS C ND1 1 
ATOM 5170 C CD2 . HIS C 3 220 ? 100.848 119.589 136.580 1.00 80.17  ? 220 HIS C CD2 1 
ATOM 5171 C CE1 . HIS C 3 220 ? 98.973  119.052 137.580 1.00 85.34  ? 220 HIS C CE1 1 
ATOM 5172 N NE2 . HIS C 3 220 ? 99.944  118.583 136.818 1.00 87.42  ? 220 HIS C NE2 1 
ATOM 5173 N N   . MET C 3 221 ? 99.485  124.527 139.103 1.00 70.71  ? 221 MET C N   1 
ATOM 5174 C CA  . MET C 3 221 ? 99.769  125.522 140.129 1.00 69.31  ? 221 MET C CA  1 
ATOM 5175 C C   . MET C 3 221 ? 99.643  124.862 141.490 1.00 73.15  ? 221 MET C C   1 
ATOM 5176 O O   . MET C 3 221 ? 98.565  124.380 141.852 1.00 80.53  ? 221 MET C O   1 
ATOM 5177 C CB  . MET C 3 221 ? 98.834  126.724 140.015 1.00 73.21  ? 221 MET C CB  1 
ATOM 5178 C CG  . MET C 3 221 ? 99.041  127.770 141.086 1.00 76.60  ? 221 MET C CG  1 
ATOM 5179 S SD  . MET C 3 221 ? 98.114  129.269 140.742 1.00 93.49  ? 221 MET C SD  1 
ATOM 5180 C CE  . MET C 3 221 ? 99.076  129.928 139.388 1.00 83.67  ? 221 MET C CE  1 
ATOM 5181 N N   . PHE C 3 222 ? 100.741 124.839 142.233 1.00 69.91  ? 222 PHE C N   1 
ATOM 5182 C CA  . PHE C 3 222 ? 100.829 124.161 143.518 1.00 70.36  ? 222 PHE C CA  1 
ATOM 5183 C C   . PHE C 3 222 ? 101.017 125.193 144.621 1.00 71.91  ? 222 PHE C C   1 
ATOM 5184 O O   . PHE C 3 222 ? 101.964 125.983 144.582 1.00 75.33  ? 222 PHE C O   1 
ATOM 5185 C CB  . PHE C 3 222 ? 101.980 123.162 143.496 1.00 70.10  ? 222 PHE C CB  1 
ATOM 5186 C CG  . PHE C 3 222 ? 101.873 122.155 142.394 1.00 76.33  ? 222 PHE C CG  1 
ATOM 5187 C CD1 . PHE C 3 222 ? 102.856 122.049 141.427 1.00 76.54  ? 222 PHE C CD1 1 
ATOM 5188 C CD2 . PHE C 3 222 ? 100.795 121.292 142.341 1.00 80.38  ? 222 PHE C CD2 1 
ATOM 5189 C CE1 . PHE C 3 222 ? 102.749 121.115 140.412 1.00 76.33  ? 222 PHE C CE1 1 
ATOM 5190 C CE2 . PHE C 3 222 ? 100.689 120.353 141.336 1.00 83.69  ? 222 PHE C CE2 1 
ATOM 5191 C CZ  . PHE C 3 222 ? 101.667 120.263 140.373 1.00 78.52  ? 222 PHE C CZ  1 
ATOM 5192 N N   . ASP C 3 223 ? 100.115 125.186 145.595 1.00 72.97  ? 223 ASP C N   1 
ATOM 5193 C CA  . ASP C 3 223 ? 100.140 126.119 146.709 1.00 74.51  ? 223 ASP C CA  1 
ATOM 5194 C C   . ASP C 3 223 ? 100.317 125.258 147.952 1.00 79.24  ? 223 ASP C C   1 
ATOM 5195 O O   . ASP C 3 223 ? 99.610  124.262 148.131 1.00 86.03  ? 223 ASP C O   1 
ATOM 5196 C CB  . ASP C 3 223 ? 98.834  126.957 146.708 1.00 82.14  ? 223 ASP C CB  1 
ATOM 5197 C CG  . ASP C 3 223 ? 98.492  127.681 148.047 1.00 92.23  ? 223 ASP C CG  1 
ATOM 5198 O OD1 . ASP C 3 223 ? 99.163  127.603 149.097 1.00 96.68  ? 223 ASP C OD1 1 
ATOM 5199 O OD2 . ASP C 3 223 ? 97.458  128.381 148.027 1.00 94.88  ? 223 ASP C OD2 1 
ATOM 5200 N N   . VAL C 3 224 ? 101.254 125.638 148.806 1.00 76.13  ? 224 VAL C N   1 
ATOM 5201 C CA  . VAL C 3 224 ? 101.653 124.801 149.928 1.00 76.02  ? 224 VAL C CA  1 
ATOM 5202 C C   . VAL C 3 224 ? 100.827 125.153 151.155 1.00 77.77  ? 224 VAL C C   1 
ATOM 5203 O O   . VAL C 3 224 ? 100.361 126.284 151.328 1.00 81.75  ? 224 VAL C O   1 
ATOM 5204 C CB  . VAL C 3 224 ? 103.163 124.924 150.212 1.00 76.46  ? 224 VAL C CB  1 
ATOM 5205 C CG1 . VAL C 3 224 ? 103.953 124.480 149.000 1.00 77.17  ? 224 VAL C CG1 1 
ATOM 5206 C CG2 . VAL C 3 224 ? 103.525 126.348 150.590 1.00 77.46  ? 224 VAL C CG2 1 
ATOM 5207 N N   . GLY C 3 225 ? 100.637 124.161 152.013 1.00 79.08  ? 225 GLY C N   1 
ATOM 5208 C CA  . GLY C 3 225 ? 99.860  124.340 153.221 1.00 79.84  ? 225 GLY C CA  1 
ATOM 5209 C C   . GLY C 3 225 ? 100.122 123.199 154.173 1.00 79.74  ? 225 GLY C C   1 
ATOM 5210 O O   . GLY C 3 225 ? 100.604 122.133 153.772 1.00 80.71  ? 225 GLY C O   1 
ATOM 5211 N N   . ALA C 3 226 ? 99.799  123.446 155.446 1.00 79.70  ? 226 ALA C N   1 
ATOM 5212 C CA  . ALA C 3 226 ? 100.053 122.519 156.555 1.00 79.89  ? 226 ALA C CA  1 
ATOM 5213 C C   . ALA C 3 226 ? 101.527 122.123 156.621 1.00 78.08  ? 226 ALA C C   1 
ATOM 5214 O O   . ALA C 3 226 ? 101.876 120.972 156.891 1.00 79.61  ? 226 ALA C O   1 
ATOM 5215 C CB  . ALA C 3 226 ? 99.151  121.283 156.475 1.00 81.01  ? 226 ALA C CB  1 
ATOM 5216 N N   . GLN C 3 227 ? 102.401 123.093 156.364 1.00 73.07  ? 227 GLN C N   1 
ATOM 5217 C CA  . GLN C 3 227 ? 103.839 122.909 156.448 1.00 69.98  ? 227 GLN C CA  1 
ATOM 5218 C C   . GLN C 3 227 ? 104.432 124.007 157.315 1.00 73.75  ? 227 GLN C C   1 
ATOM 5219 O O   . GLN C 3 227 ? 103.898 125.117 157.388 1.00 76.71  ? 227 GLN C O   1 
ATOM 5220 C CB  . GLN C 3 227 ? 104.500 122.930 155.070 1.00 67.50  ? 227 GLN C CB  1 
ATOM 5221 C CG  . GLN C 3 227 ? 103.932 121.927 154.096 1.00 68.99  ? 227 GLN C CG  1 
ATOM 5222 C CD  . GLN C 3 227 ? 104.833 120.733 153.930 1.00 74.71  ? 227 GLN C CD  1 
ATOM 5223 O OE1 . GLN C 3 227 ? 105.395 120.236 154.902 1.00 77.10  ? 227 GLN C OE1 1 
ATOM 5224 N NE2 . GLN C 3 227 ? 104.977 120.262 152.699 1.00 79.56  ? 227 GLN C NE2 1 
ATOM 5225 N N   . ARG C 3 228 ? 105.541 123.685 157.972 1.00 74.69  ? 228 ARG C N   1 
ATOM 5226 C CA  . ARG C 3 228 ? 106.188 124.636 158.858 1.00 77.68  ? 228 ARG C CA  1 
ATOM 5227 C C   . ARG C 3 228 ? 106.879 125.733 158.056 1.00 80.25  ? 228 ARG C C   1 
ATOM 5228 O O   . ARG C 3 228 ? 107.094 125.618 156.847 1.00 76.98  ? 228 ARG C O   1 
ATOM 5229 C CB  . ARG C 3 228 ? 107.200 123.930 159.754 1.00 78.96  ? 228 ARG C CB  1 
ATOM 5230 C CG  . ARG C 3 228 ? 106.580 123.152 160.894 1.00 78.26  ? 228 ARG C CG  1 
ATOM 5231 C CD  . ARG C 3 228 ? 107.505 123.107 162.095 1.00 84.48  ? 228 ARG C CD  1 
ATOM 5232 N NE  . ARG C 3 228 ? 108.905 123.272 161.722 1.00 90.97  ? 228 ARG C NE  1 
ATOM 5233 C CZ  . ARG C 3 228 ? 109.745 122.271 161.500 1.00 94.70  ? 228 ARG C CZ  1 
ATOM 5234 N NH1 . ARG C 3 228 ? 109.359 121.010 161.597 1.00 96.04  ? 228 ARG C NH1 1 
ATOM 5235 N NH2 . ARG C 3 228 ? 111.004 122.541 161.170 1.00 91.86  ? 228 ARG C NH2 1 
ATOM 5236 N N   . ASP C 3 229 ? 107.236 126.812 158.754 1.00 85.04  ? 229 ASP C N   1 
ATOM 5237 C CA  . ASP C 3 229 ? 107.895 127.938 158.105 1.00 88.77  ? 229 ASP C CA  1 
ATOM 5238 C C   . ASP C 3 229 ? 109.337 127.641 157.720 1.00 83.17  ? 229 ASP C C   1 
ATOM 5239 O O   . ASP C 3 229 ? 109.926 128.418 156.961 1.00 84.13  ? 229 ASP C O   1 
ATOM 5240 C CB  . ASP C 3 229 ? 107.847 129.175 159.006 1.00 96.02  ? 229 ASP C CB  1 
ATOM 5241 C CG  . ASP C 3 229 ? 108.226 128.870 160.441 1.00 98.03  ? 229 ASP C CG  1 
ATOM 5242 O OD1 . ASP C 3 229 ? 108.604 127.716 160.733 1.00 97.75  ? 229 ASP C OD1 1 
ATOM 5243 O OD2 . ASP C 3 229 ? 108.150 129.792 161.279 1.00 97.85  ? 229 ASP C OD2 1 
ATOM 5244 N N   . GLU C 3 230 ? 109.919 126.551 158.217 1.00 79.61  ? 230 GLU C N   1 
ATOM 5245 C CA  . GLU C 3 230 ? 111.270 126.154 157.829 1.00 81.02  ? 230 GLU C CA  1 
ATOM 5246 C C   . GLU C 3 230 ? 111.208 125.576 156.419 1.00 75.30  ? 230 GLU C C   1 
ATOM 5247 O O   . GLU C 3 230 ? 111.138 124.364 156.204 1.00 76.55  ? 230 GLU C O   1 
ATOM 5248 C CB  . GLU C 3 230 ? 111.853 125.160 158.826 1.00 87.13  ? 230 GLU C CB  1 
ATOM 5249 C CG  . GLU C 3 230 ? 112.332 125.793 160.124 1.00 92.08  ? 230 GLU C CG  1 
ATOM 5250 C CD  . GLU C 3 230 ? 113.230 124.871 160.926 1.00 95.78  ? 230 GLU C CD  1 
ATOM 5251 O OE1 . GLU C 3 230 ? 113.985 124.090 160.310 1.00 94.65  ? 230 GLU C OE1 1 
ATOM 5252 O OE2 . GLU C 3 230 ? 113.183 124.928 162.173 1.00 100.46 ? 230 GLU C OE2 1 
ATOM 5253 N N   . ARG C 3 231 ? 111.243 126.473 155.437 1.00 69.39  ? 231 ARG C N   1 
ATOM 5254 C CA  . ARG C 3 231 ? 111.031 126.118 154.044 1.00 66.02  ? 231 ARG C CA  1 
ATOM 5255 C C   . ARG C 3 231 ? 112.326 125.900 153.290 1.00 63.07  ? 231 ARG C C   1 
ATOM 5256 O O   . ARG C 3 231 ? 112.321 125.925 152.056 1.00 66.53  ? 231 ARG C O   1 
ATOM 5257 C CB  . ARG C 3 231 ? 110.217 127.201 153.339 1.00 69.59  ? 231 ARG C CB  1 
ATOM 5258 C CG  . ARG C 3 231 ? 110.659 128.603 153.672 1.00 70.82  ? 231 ARG C CG  1 
ATOM 5259 C CD  . ARG C 3 231 ? 109.977 129.609 152.775 1.00 70.64  ? 231 ARG C CD  1 
ATOM 5260 N NE  . ARG C 3 231 ? 108.576 129.798 153.121 1.00 74.84  ? 231 ARG C NE  1 
ATOM 5261 C CZ  . ARG C 3 231 ? 108.140 130.704 153.983 1.00 81.39  ? 231 ARG C CZ  1 
ATOM 5262 N NH1 . ARG C 3 231 ? 108.974 131.512 154.615 1.00 79.01  ? 231 ARG C NH1 1 
ATOM 5263 N NH2 . ARG C 3 231 ? 106.835 130.806 154.213 1.00 90.56  ? 231 ARG C NH2 1 
ATOM 5264 N N   . ARG C 3 232 ? 113.432 125.700 154.002 1.00 62.92  ? 232 ARG C N   1 
ATOM 5265 C CA  . ARG C 3 232 ? 114.731 125.642 153.349 1.00 62.75  ? 232 ARG C CA  1 
ATOM 5266 C C   . ARG C 3 232 ? 114.895 124.370 152.533 1.00 64.96  ? 232 ARG C C   1 
ATOM 5267 O O   . ARG C 3 232 ? 115.494 124.404 151.452 1.00 67.45  ? 232 ARG C O   1 
ATOM 5268 C CB  . ARG C 3 232 ? 115.837 125.767 154.396 1.00 57.54  ? 232 ARG C CB  1 
ATOM 5269 C CG  . ARG C 3 232 ? 117.056 124.908 154.209 1.00 57.19  ? 232 ARG C CG  1 
ATOM 5270 C CD  . ARG C 3 232 ? 118.039 125.129 155.344 1.00 61.17  ? 232 ARG C CD  1 
ATOM 5271 N NE  . ARG C 3 232 ? 117.696 124.368 156.539 1.00 63.33  ? 232 ARG C NE  1 
ATOM 5272 C CZ  . ARG C 3 232 ? 117.087 124.869 157.605 1.00 62.50  ? 232 ARG C CZ  1 
ATOM 5273 N NH1 . ARG C 3 232 ? 116.715 126.135 157.656 1.00 61.42  ? 232 ARG C NH1 1 
ATOM 5274 N NH2 . ARG C 3 232 ? 116.848 124.078 158.646 1.00 66.03  ? 232 ARG C NH2 1 
ATOM 5275 N N   . LYS C 3 233 ? 114.340 123.253 152.997 1.00 63.66  ? 233 LYS C N   1 
ATOM 5276 C CA  . LYS C 3 233 ? 114.699 121.987 152.381 1.00 62.36  ? 233 LYS C CA  1 
ATOM 5277 C C   . LYS C 3 233 ? 113.583 121.372 151.544 1.00 64.18  ? 233 LYS C C   1 
ATOM 5278 O O   . LYS C 3 233 ? 113.872 120.529 150.692 1.00 68.31  ? 233 LYS C O   1 
ATOM 5279 C CB  . LYS C 3 233 ? 115.179 121.008 153.454 1.00 60.36  ? 233 LYS C CB  1 
ATOM 5280 C CG  . LYS C 3 233 ? 116.628 121.313 153.826 1.00 67.43  ? 233 LYS C CG  1 
ATOM 5281 C CD  . LYS C 3 233 ? 117.562 120.136 153.816 1.00 71.75  ? 233 LYS C CD  1 
ATOM 5282 C CE  . LYS C 3 233 ? 118.145 119.920 152.427 1.00 76.05  ? 233 LYS C CE  1 
ATOM 5283 N NZ  . LYS C 3 233 ? 119.408 120.703 152.246 1.00 75.76  ? 233 LYS C NZ  1 
ATOM 5284 N N   . TRP C 3 234 ? 112.322 121.771 151.728 1.00 62.54  ? 234 TRP C N   1 
ATOM 5285 C CA  . TRP C 3 234 ? 111.302 121.288 150.803 1.00 60.98  ? 234 TRP C CA  1 
ATOM 5286 C C   . TRP C 3 234 ? 111.170 122.147 149.558 1.00 63.75  ? 234 TRP C C   1 
ATOM 5287 O O   . TRP C 3 234 ? 110.468 121.746 148.624 1.00 67.66  ? 234 TRP C O   1 
ATOM 5288 C CB  . TRP C 3 234 ? 109.926 121.165 151.474 1.00 59.32  ? 234 TRP C CB  1 
ATOM 5289 C CG  . TRP C 3 234 ? 109.293 122.418 152.029 1.00 61.16  ? 234 TRP C CG  1 
ATOM 5290 C CD1 . TRP C 3 234 ? 109.260 122.796 153.337 1.00 65.39  ? 234 TRP C CD1 1 
ATOM 5291 C CD2 . TRP C 3 234 ? 108.556 123.420 151.309 1.00 61.20  ? 234 TRP C CD2 1 
ATOM 5292 N NE1 . TRP C 3 234 ? 108.565 123.969 153.477 1.00 68.10  ? 234 TRP C NE1 1 
ATOM 5293 C CE2 . TRP C 3 234 ? 108.130 124.377 152.246 1.00 64.32  ? 234 TRP C CE2 1 
ATOM 5294 C CE3 . TRP C 3 234 ? 108.224 123.605 149.965 1.00 63.52  ? 234 TRP C CE3 1 
ATOM 5295 C CZ2 . TRP C 3 234 ? 107.393 125.499 151.883 1.00 65.31  ? 234 TRP C CZ2 1 
ATOM 5296 C CZ3 . TRP C 3 234 ? 107.500 124.721 149.608 1.00 66.17  ? 234 TRP C CZ3 1 
ATOM 5297 C CH2 . TRP C 3 234 ? 107.091 125.652 150.562 1.00 66.79  ? 234 TRP C CH2 1 
ATOM 5298 N N   . ILE C 3 235 ? 111.813 123.315 149.511 1.00 60.31  ? 235 ILE C N   1 
ATOM 5299 C CA  . ILE C 3 235 ? 111.708 124.151 148.321 1.00 60.73  ? 235 ILE C CA  1 
ATOM 5300 C C   . ILE C 3 235 ? 112.699 123.709 147.258 1.00 63.73  ? 235 ILE C C   1 
ATOM 5301 O O   . ILE C 3 235 ? 112.600 124.136 146.100 1.00 67.71  ? 235 ILE C O   1 
ATOM 5302 C CB  . ILE C 3 235 ? 111.887 125.628 148.720 1.00 63.22  ? 235 ILE C CB  1 
ATOM 5303 C CG1 . ILE C 3 235 ? 111.345 126.565 147.639 1.00 70.90  ? 235 ILE C CG1 1 
ATOM 5304 C CG2 . ILE C 3 235 ? 113.352 125.935 148.943 1.00 62.42  ? 235 ILE C CG2 1 
ATOM 5305 C CD1 . ILE C 3 235 ? 110.766 127.837 148.187 1.00 68.48  ? 235 ILE C CD1 1 
ATOM 5306 N N   . GLN C 3 236 ? 113.631 122.820 147.609 1.00 60.98  ? 236 GLN C N   1 
ATOM 5307 C CA  . GLN C 3 236 ? 114.549 122.264 146.626 1.00 61.32  ? 236 GLN C CA  1 
ATOM 5308 C C   . GLN C 3 236 ? 113.847 121.351 145.634 1.00 63.40  ? 236 GLN C C   1 
ATOM 5309 O O   . GLN C 3 236 ? 114.401 121.079 144.564 1.00 67.61  ? 236 GLN C O   1 
ATOM 5310 C CB  . GLN C 3 236 ? 115.666 121.498 147.328 1.00 64.03  ? 236 GLN C CB  1 
ATOM 5311 C CG  . GLN C 3 236 ? 116.612 122.376 148.117 1.00 69.46  ? 236 GLN C CG  1 
ATOM 5312 C CD  . GLN C 3 236 ? 117.586 121.570 148.946 1.00 69.93  ? 236 GLN C CD  1 
ATOM 5313 O OE1 . GLN C 3 236 ? 117.434 120.358 149.096 1.00 65.40  ? 236 GLN C OE1 1 
ATOM 5314 N NE2 . GLN C 3 236 ? 118.595 122.238 149.492 1.00 75.05  ? 236 GLN C NE2 1 
ATOM 5315 N N   . CYS C 3 237 ? 112.653 120.861 145.972 1.00 62.66  ? 237 CYS C N   1 
ATOM 5316 C CA  . CYS C 3 237 ? 111.859 120.102 145.015 1.00 63.47  ? 237 CYS C CA  1 
ATOM 5317 C C   . CYS C 3 237 ? 111.416 120.979 143.853 1.00 63.98  ? 237 CYS C C   1 
ATOM 5318 O O   . CYS C 3 237 ? 111.410 120.539 142.698 1.00 67.33  ? 237 CYS C O   1 
ATOM 5319 C CB  . CYS C 3 237 ? 110.646 119.492 145.713 1.00 64.26  ? 237 CYS C CB  1 
ATOM 5320 S SG  . CYS C 3 237 ? 111.031 118.157 146.854 1.00 82.00  ? 237 CYS C SG  1 
ATOM 5321 N N   . PHE C 3 238 ? 111.047 122.224 144.139 1.00 61.21  ? 238 PHE C N   1 
ATOM 5322 C CA  . PHE C 3 238 ? 110.511 123.127 143.124 1.00 62.12  ? 238 PHE C CA  1 
ATOM 5323 C C   . PHE C 3 238 ? 111.647 123.896 142.450 1.00 66.40  ? 238 PHE C C   1 
ATOM 5324 O O   . PHE C 3 238 ? 111.802 125.110 142.594 1.00 70.17  ? 238 PHE C O   1 
ATOM 5325 C CB  . PHE C 3 238 ? 109.492 124.073 143.745 1.00 61.14  ? 238 PHE C CB  1 
ATOM 5326 C CG  . PHE C 3 238 ? 108.412 123.381 144.515 1.00 62.32  ? 238 PHE C CG  1 
ATOM 5327 C CD1 . PHE C 3 238 ? 107.326 122.833 143.863 1.00 66.91  ? 238 PHE C CD1 1 
ATOM 5328 C CD2 . PHE C 3 238 ? 108.475 123.291 145.892 1.00 62.83  ? 238 PHE C CD2 1 
ATOM 5329 C CE1 . PHE C 3 238 ? 106.326 122.199 144.568 1.00 69.55  ? 238 PHE C CE1 1 
ATOM 5330 C CE2 . PHE C 3 238 ? 107.479 122.659 146.604 1.00 68.42  ? 238 PHE C CE2 1 
ATOM 5331 C CZ  . PHE C 3 238 ? 106.403 122.112 145.941 1.00 71.88  ? 238 PHE C CZ  1 
ATOM 5332 N N   . ASN C 3 239 ? 112.457 123.154 141.694 1.00 64.27  ? 239 ASN C N   1 
ATOM 5333 C CA  . ASN C 3 239 ? 113.452 123.765 140.827 1.00 64.75  ? 239 ASN C CA  1 
ATOM 5334 C C   . ASN C 3 239 ? 113.157 123.576 139.351 1.00 68.66  ? 239 ASN C C   1 
ATOM 5335 O O   . ASN C 3 239 ? 113.597 124.398 138.542 1.00 70.00  ? 239 ASN C O   1 
ATOM 5336 C CB  . ASN C 3 239 ? 114.846 123.201 141.117 1.00 63.94  ? 239 ASN C CB  1 
ATOM 5337 C CG  . ASN C 3 239 ? 114.921 121.717 140.893 1.00 70.43  ? 239 ASN C CG  1 
ATOM 5338 O OD1 . ASN C 3 239 ? 113.937 121.005 141.078 1.00 72.16  ? 239 ASN C OD1 1 
ATOM 5339 N ND2 . ASN C 3 239 ? 116.084 121.238 140.475 1.00 73.05  ? 239 ASN C ND2 1 
ATOM 5340 N N   . ASP C 3 240 ? 112.430 122.527 138.983 1.00 71.21  ? 240 ASP C N   1 
ATOM 5341 C CA  . ASP C 3 240 ? 112.051 122.287 137.600 1.00 73.58  ? 240 ASP C CA  1 
ATOM 5342 C C   . ASP C 3 240 ? 110.782 123.025 137.207 1.00 68.21  ? 240 ASP C C   1 
ATOM 5343 O O   . ASP C 3 240 ? 110.361 122.929 136.051 1.00 69.50  ? 240 ASP C O   1 
ATOM 5344 C CB  . ASP C 3 240 ? 111.870 120.787 137.352 1.00 81.33  ? 240 ASP C CB  1 
ATOM 5345 C CG  . ASP C 3 240 ? 111.122 120.096 138.476 1.00 83.76  ? 240 ASP C CG  1 
ATOM 5346 O OD1 . ASP C 3 240 ? 111.737 119.838 139.531 1.00 83.15  ? 240 ASP C OD1 1 
ATOM 5347 O OD2 . ASP C 3 240 ? 109.919 119.810 138.302 1.00 80.71  ? 240 ASP C OD2 1 
ATOM 5348 N N   . VAL C 3 241 ? 110.158 123.742 138.142 1.00 63.99  ? 241 VAL C N   1 
ATOM 5349 C CA  . VAL C 3 241 ? 108.991 124.543 137.812 1.00 61.06  ? 241 VAL C CA  1 
ATOM 5350 C C   . VAL C 3 241 ? 109.414 125.713 136.933 1.00 60.12  ? 241 VAL C C   1 
ATOM 5351 O O   . VAL C 3 241 ? 110.544 126.212 137.020 1.00 63.55  ? 241 VAL C O   1 
ATOM 5352 C CB  . VAL C 3 241 ? 108.285 125.025 139.091 1.00 61.05  ? 241 VAL C CB  1 
ATOM 5353 C CG1 . VAL C 3 241 ? 107.670 123.850 139.821 1.00 61.07  ? 241 VAL C CG1 1 
ATOM 5354 C CG2 . VAL C 3 241 ? 109.255 125.755 139.996 1.00 61.47  ? 241 VAL C CG2 1 
ATOM 5355 N N   . THR C 3 242 ? 108.510 126.131 136.046 1.00 57.79  ? 242 THR C N   1 
ATOM 5356 C CA  . THR C 3 242 ? 108.843 127.192 135.101 1.00 58.94  ? 242 THR C CA  1 
ATOM 5357 C C   . THR C 3 242 ? 108.992 128.533 135.802 1.00 62.68  ? 242 THR C C   1 
ATOM 5358 O O   . THR C 3 242 ? 109.879 129.322 135.459 1.00 65.45  ? 242 THR C O   1 
ATOM 5359 C CB  . THR C 3 242 ? 107.783 127.277 134.005 1.00 60.86  ? 242 THR C CB  1 
ATOM 5360 O OG1 . THR C 3 242 ? 106.682 128.069 134.462 1.00 64.94  ? 242 THR C OG1 1 
ATOM 5361 C CG2 . THR C 3 242 ? 107.289 125.893 133.642 1.00 64.18  ? 242 THR C CG2 1 
ATOM 5362 N N   . ALA C 3 243 ? 108.145 128.806 136.789 1.00 61.32  ? 243 ALA C N   1 
ATOM 5363 C CA  . ALA C 3 243 ? 108.212 130.061 137.514 1.00 60.29  ? 243 ALA C CA  1 
ATOM 5364 C C   . ALA C 3 243 ? 107.623 129.877 138.901 1.00 59.09  ? 243 ALA C C   1 
ATOM 5365 O O   . ALA C 3 243 ? 106.698 129.086 139.100 1.00 63.41  ? 243 ALA C O   1 
ATOM 5366 C CB  . ALA C 3 243 ? 107.477 131.179 136.773 1.00 60.15  ? 243 ALA C CB  1 
ATOM 5367 N N   . ILE C 3 244 ? 108.168 130.620 139.855 1.00 54.00  ? 244 ILE C N   1 
ATOM 5368 C CA  . ILE C 3 244 ? 107.687 130.625 141.229 1.00 52.60  ? 244 ILE C CA  1 
ATOM 5369 C C   . ILE C 3 244 ? 106.937 131.930 141.438 1.00 53.39  ? 244 ILE C C   1 
ATOM 5370 O O   . ILE C 3 244 ? 107.541 133.005 141.469 1.00 59.90  ? 244 ILE C O   1 
ATOM 5371 C CB  . ILE C 3 244 ? 108.838 130.477 142.229 1.00 55.40  ? 244 ILE C CB  1 
ATOM 5372 C CG1 . ILE C 3 244 ? 109.539 129.133 142.034 1.00 63.73  ? 244 ILE C CG1 1 
ATOM 5373 C CG2 . ILE C 3 244 ? 108.329 130.619 143.649 1.00 59.33  ? 244 ILE C CG2 1 
ATOM 5374 C CD1 . ILE C 3 244 ? 110.640 128.862 143.035 1.00 71.90  ? 244 ILE C CD1 1 
ATOM 5375 N N   . ILE C 3 245 ? 105.618 131.844 141.583 1.00 52.76  ? 245 ILE C N   1 
ATOM 5376 C CA  . ILE C 3 245 ? 104.813 133.041 141.785 1.00 52.24  ? 245 ILE C CA  1 
ATOM 5377 C C   . ILE C 3 245 ? 105.002 133.523 143.216 1.00 56.19  ? 245 ILE C C   1 
ATOM 5378 O O   . ILE C 3 245 ? 104.777 132.777 144.175 1.00 63.01  ? 245 ILE C O   1 
ATOM 5379 C CB  . ILE C 3 245 ? 103.339 132.763 141.476 1.00 51.24  ? 245 ILE C CB  1 
ATOM 5380 C CG1 . ILE C 3 245 ? 103.162 132.520 139.982 1.00 52.27  ? 245 ILE C CG1 1 
ATOM 5381 C CG2 . ILE C 3 245 ? 102.467 133.899 141.969 1.00 52.66  ? 245 ILE C CG2 1 
ATOM 5382 C CD1 . ILE C 3 245 ? 101.733 132.469 139.540 1.00 58.57  ? 245 ILE C CD1 1 
ATOM 5383 N N   . PHE C 3 246 ? 105.419 134.772 143.363 1.00 53.16  ? 246 PHE C N   1 
ATOM 5384 C CA  . PHE C 3 246 ? 105.721 135.367 144.656 1.00 53.50  ? 246 PHE C CA  1 
ATOM 5385 C C   . PHE C 3 246 ? 104.736 136.499 144.903 1.00 58.64  ? 246 PHE C C   1 
ATOM 5386 O O   . PHE C 3 246 ? 104.853 137.573 144.304 1.00 66.52  ? 246 PHE C O   1 
ATOM 5387 C CB  . PHE C 3 246 ? 107.158 135.871 144.687 1.00 52.87  ? 246 PHE C CB  1 
ATOM 5388 C CG  . PHE C 3 246 ? 107.724 136.002 146.060 1.00 56.00  ? 246 PHE C CG  1 
ATOM 5389 C CD1 . PHE C 3 246 ? 107.604 134.975 146.973 1.00 62.12  ? 246 PHE C CD1 1 
ATOM 5390 C CD2 . PHE C 3 246 ? 108.384 137.154 146.437 1.00 58.98  ? 246 PHE C CD2 1 
ATOM 5391 C CE1 . PHE C 3 246 ? 108.126 135.099 148.238 1.00 62.76  ? 246 PHE C CE1 1 
ATOM 5392 C CE2 . PHE C 3 246 ? 108.910 137.282 147.697 1.00 63.11  ? 246 PHE C CE2 1 
ATOM 5393 C CZ  . PHE C 3 246 ? 108.779 136.256 148.598 1.00 61.30  ? 246 PHE C CZ  1 
ATOM 5394 N N   . VAL C 3 247 ? 103.773 136.262 145.782 1.00 56.52  ? 247 VAL C N   1 
ATOM 5395 C CA  . VAL C 3 247 ? 102.781 137.258 146.157 1.00 60.97  ? 247 VAL C CA  1 
ATOM 5396 C C   . VAL C 3 247 ? 103.254 137.945 147.426 1.00 67.73  ? 247 VAL C C   1 
ATOM 5397 O O   . VAL C 3 247 ? 103.547 137.281 148.429 1.00 73.93  ? 247 VAL C O   1 
ATOM 5398 C CB  . VAL C 3 247 ? 101.401 136.615 146.359 1.00 67.40  ? 247 VAL C CB  1 
ATOM 5399 C CG1 . VAL C 3 247 ? 100.326 137.679 146.424 1.00 77.25  ? 247 VAL C CG1 1 
ATOM 5400 C CG2 . VAL C 3 247 ? 101.114 135.629 145.242 1.00 65.08  ? 247 VAL C CG2 1 
ATOM 5401 N N   . VAL C 3 248 ? 103.334 139.270 147.389 1.00 69.03  ? 248 VAL C N   1 
ATOM 5402 C CA  . VAL C 3 248 ? 103.877 140.059 148.486 1.00 72.27  ? 248 VAL C CA  1 
ATOM 5403 C C   . VAL C 3 248 ? 102.818 141.056 148.929 1.00 80.71  ? 248 VAL C C   1 
ATOM 5404 O O   . VAL C 3 248 ? 102.288 141.811 148.107 1.00 85.78  ? 248 VAL C O   1 
ATOM 5405 C CB  . VAL C 3 248 ? 105.173 140.776 148.068 1.00 74.61  ? 248 VAL C CB  1 
ATOM 5406 C CG1 . VAL C 3 248 ? 105.477 141.950 148.987 1.00 80.27  ? 248 VAL C CG1 1 
ATOM 5407 C CG2 . VAL C 3 248 ? 106.327 139.797 148.039 1.00 73.35  ? 248 VAL C CG2 1 
ATOM 5408 N N   . ALA C 3 249 ? 102.505 141.050 150.222 1.00 84.29  ? 249 ALA C N   1 
ATOM 5409 C CA  . ALA C 3 249 ? 101.601 142.045 150.781 1.00 95.30  ? 249 ALA C CA  1 
ATOM 5410 C C   . ALA C 3 249 ? 102.317 143.383 150.887 1.00 101.70 ? 249 ALA C C   1 
ATOM 5411 O O   . ALA C 3 249 ? 103.006 143.649 151.875 1.00 106.42 ? 249 ALA C O   1 
ATOM 5412 C CB  . ALA C 3 249 ? 101.082 141.599 152.149 1.00 98.41  ? 249 ALA C CB  1 
ATOM 5413 N N   . SER C 3 250 ? 102.144 144.237 149.881 1.00 101.86 ? 250 SER C N   1 
ATOM 5414 C CA  . SER C 3 250 ? 102.914 145.467 149.745 1.00 102.56 ? 250 SER C CA  1 
ATOM 5415 C C   . SER C 3 250 ? 102.339 146.635 150.535 1.00 101.26 ? 250 SER C C   1 
ATOM 5416 O O   . SER C 3 250 ? 102.605 147.787 150.181 1.00 103.30 ? 250 SER C O   1 
ATOM 5417 C CB  . SER C 3 250 ? 103.023 145.854 148.267 1.00 100.74 ? 250 SER C CB  1 
ATOM 5418 O OG  . SER C 3 250 ? 103.685 147.097 148.114 1.00 104.69 ? 250 SER C OG  1 
ATOM 5419 N N   . SER C 3 251 ? 101.559 146.379 151.580 1.00 101.75 ? 251 SER C N   1 
ATOM 5420 C CA  . SER C 3 251 ? 101.009 147.446 152.402 1.00 110.42 ? 251 SER C CA  1 
ATOM 5421 C C   . SER C 3 251 ? 101.464 147.398 153.850 1.00 116.81 ? 251 SER C C   1 
ATOM 5422 O O   . SER C 3 251 ? 101.497 148.441 154.506 1.00 118.13 ? 251 SER C O   1 
ATOM 5423 C CB  . SER C 3 251 ? 99.477  147.409 152.365 1.00 113.53 ? 251 SER C CB  1 
ATOM 5424 O OG  . SER C 3 251 ? 98.993  147.610 151.049 1.00 113.88 ? 251 SER C OG  1 
ATOM 5425 N N   . SER C 3 252 ? 101.815 146.222 154.362 1.00 119.93 ? 252 SER C N   1 
ATOM 5426 C CA  . SER C 3 252 ? 102.211 146.068 155.761 1.00 122.49 ? 252 SER C CA  1 
ATOM 5427 C C   . SER C 3 252 ? 103.684 146.433 155.896 1.00 119.55 ? 252 SER C C   1 
ATOM 5428 O O   . SER C 3 252 ? 104.573 145.591 155.763 1.00 113.41 ? 252 SER C O   1 
ATOM 5429 C CB  . SER C 3 252 ? 101.942 144.648 156.243 1.00 113.25 ? 252 SER C CB  1 
ATOM 5430 O OG  . SER C 3 252 ? 100.591 144.282 156.024 1.00 111.98 ? 252 SER C OG  1 
ATOM 5431 N N   . TYR C 3 253 ? 103.947 147.709 156.163 1.00 120.46 ? 253 TYR C N   1 
ATOM 5432 C CA  . TYR C 3 253 ? 105.313 148.170 156.382 1.00 114.82 ? 253 TYR C CA  1 
ATOM 5433 C C   . TYR C 3 253 ? 105.435 148.907 157.713 1.00 113.15 ? 253 TYR C C   1 
ATOM 5434 O O   . TYR C 3 253 ? 104.498 148.928 158.510 1.00 114.54 ? 253 TYR C O   1 
ATOM 5435 C CB  . TYR C 3 253 ? 105.776 149.070 155.233 1.00 113.33 ? 253 TYR C CB  1 
ATOM 5436 C CG  . TYR C 3 253 ? 104.697 149.956 154.647 1.00 116.78 ? 253 TYR C CG  1 
ATOM 5437 C CD1 . TYR C 3 253 ? 104.151 151.001 155.383 1.00 115.72 ? 253 TYR C CD1 1 
ATOM 5438 C CD2 . TYR C 3 253 ? 104.231 149.751 153.354 1.00 115.11 ? 253 TYR C CD2 1 
ATOM 5439 C CE1 . TYR C 3 253 ? 103.170 151.814 154.850 1.00 115.23 ? 253 TYR C CE1 1 
ATOM 5440 C CE2 . TYR C 3 253 ? 103.248 150.560 152.814 1.00 113.40 ? 253 TYR C CE2 1 
ATOM 5441 C CZ  . TYR C 3 253 ? 102.723 151.588 153.568 1.00 114.90 ? 253 TYR C CZ  1 
ATOM 5442 O OH  . TYR C 3 253 ? 101.747 152.398 153.039 1.00 114.58 ? 253 TYR C OH  1 
ATOM 5443 N N   . GLN C 3 262 ? 105.985 139.920 163.191 1.00 109.50 ? 262 GLN C N   1 
ATOM 5444 C CA  . GLN C 3 262 ? 106.978 140.759 162.530 1.00 108.14 ? 262 GLN C CA  1 
ATOM 5445 C C   . GLN C 3 262 ? 106.506 142.206 162.452 1.00 107.40 ? 262 GLN C C   1 
ATOM 5446 O O   . GLN C 3 262 ? 105.365 142.474 162.074 1.00 105.95 ? 262 GLN C O   1 
ATOM 5447 C CB  . GLN C 3 262 ? 107.280 140.227 161.128 1.00 102.28 ? 262 GLN C CB  1 
ATOM 5448 N N   . THR C 3 263 ? 107.390 143.136 162.821 1.00 107.05 ? 263 THR C N   1 
ATOM 5449 C CA  . THR C 3 263 ? 107.048 144.553 162.748 1.00 105.63 ? 263 THR C CA  1 
ATOM 5450 C C   . THR C 3 263 ? 106.954 145.025 161.303 1.00 101.80 ? 263 THR C C   1 
ATOM 5451 O O   . THR C 3 263 ? 106.077 145.827 160.962 1.00 102.96 ? 263 THR C O   1 
ATOM 5452 C CB  . THR C 3 263 ? 108.075 145.385 163.516 1.00 106.53 ? 263 THR C CB  1 
ATOM 5453 O OG1 . THR C 3 263 ? 109.384 145.135 162.991 1.00 106.02 ? 263 THR C OG1 1 
ATOM 5454 C CG2 . THR C 3 263 ? 108.050 145.029 164.995 1.00 104.69 ? 263 THR C CG2 1 
ATOM 5455 N N   . ASN C 3 264 ? 107.845 144.542 160.443 1.00 99.00  ? 264 ASN C N   1 
ATOM 5456 C CA  . ASN C 3 264 ? 107.831 144.869 159.025 1.00 95.85  ? 264 ASN C CA  1 
ATOM 5457 C C   . ASN C 3 264 ? 107.623 143.596 158.223 1.00 94.32  ? 264 ASN C C   1 
ATOM 5458 O O   . ASN C 3 264 ? 108.379 142.631 158.375 1.00 96.85  ? 264 ASN C O   1 
ATOM 5459 C CB  . ASN C 3 264 ? 109.134 145.546 158.600 1.00 93.15  ? 264 ASN C CB  1 
ATOM 5460 C CG  . ASN C 3 264 ? 109.037 146.195 157.233 1.00 96.89  ? 264 ASN C CG  1 
ATOM 5461 O OD1 . ASN C 3 264 ? 107.986 146.177 156.594 1.00 99.71  ? 264 ASN C OD1 1 
ATOM 5462 N ND2 . ASN C 3 264 ? 110.139 146.775 156.776 1.00 96.53  ? 264 ASN C ND2 1 
ATOM 5463 N N   . ARG C 3 265 ? 106.601 143.597 157.370 1.00 90.06  ? 265 ARG C N   1 
ATOM 5464 C CA  . ARG C 3 265 ? 106.391 142.463 156.481 1.00 88.50  ? 265 ARG C CA  1 
ATOM 5465 C C   . ARG C 3 265 ? 107.161 142.624 155.181 1.00 83.80  ? 265 ARG C C   1 
ATOM 5466 O O   . ARG C 3 265 ? 107.493 141.625 154.530 1.00 83.02  ? 265 ARG C O   1 
ATOM 5467 C CB  . ARG C 3 265 ? 104.900 142.287 156.196 1.00 94.36  ? 265 ARG C CB  1 
ATOM 5468 C CG  . ARG C 3 265 ? 104.485 140.848 155.943 1.00 97.61  ? 265 ARG C CG  1 
ATOM 5469 C CD  . ARG C 3 265 ? 103.006 140.645 156.218 1.00 100.80 ? 265 ARG C CD  1 
ATOM 5470 N NE  . ARG C 3 265 ? 102.750 140.295 157.609 1.00 104.26 ? 265 ARG C NE  1 
ATOM 5471 C CZ  . ARG C 3 265 ? 102.505 139.064 158.039 1.00 103.70 ? 265 ARG C CZ  1 
ATOM 5472 N NH1 . ARG C 3 265 ? 102.473 138.035 157.207 1.00 102.83 ? 265 ARG C NH1 1 
ATOM 5473 N NH2 . ARG C 3 265 ? 102.287 138.861 159.335 1.00 105.51 ? 265 ARG C NH2 1 
ATOM 5474 N N   . LEU C 3 266 ? 107.460 143.867 154.799 1.00 82.00  ? 266 LEU C N   1 
ATOM 5475 C CA  . LEU C 3 266 ? 108.162 144.108 153.546 1.00 82.72  ? 266 LEU C CA  1 
ATOM 5476 C C   . LEU C 3 266 ? 109.594 143.598 153.596 1.00 80.59  ? 266 LEU C C   1 
ATOM 5477 O O   . LEU C 3 266 ? 110.084 143.042 152.611 1.00 81.98  ? 266 LEU C O   1 
ATOM 5478 C CB  . LEU C 3 266 ? 108.138 145.594 153.200 1.00 88.54  ? 266 LEU C CB  1 
ATOM 5479 C CG  . LEU C 3 266 ? 107.165 146.007 152.095 1.00 92.16  ? 266 LEU C CG  1 
ATOM 5480 C CD1 . LEU C 3 266 ? 107.717 145.608 150.737 1.00 85.04  ? 266 LEU C CD1 1 
ATOM 5481 C CD2 . LEU C 3 266 ? 105.782 145.416 152.310 1.00 97.94  ? 266 LEU C CD2 1 
ATOM 5482 N N   . GLN C 3 267 ? 110.281 143.769 154.726 1.00 79.31  ? 267 GLN C N   1 
ATOM 5483 C CA  . GLN C 3 267 ? 111.650 143.272 154.828 1.00 76.20  ? 267 GLN C CA  1 
ATOM 5484 C C   . GLN C 3 267 ? 111.684 141.748 154.817 1.00 77.51  ? 267 GLN C C   1 
ATOM 5485 O O   . GLN C 3 267 ? 112.615 141.140 154.265 1.00 78.81  ? 267 GLN C O   1 
ATOM 5486 C CB  . GLN C 3 267 ? 112.311 143.811 156.091 1.00 77.67  ? 267 GLN C CB  1 
ATOM 5487 C CG  . GLN C 3 267 ? 112.970 145.164 155.923 1.00 82.40  ? 267 GLN C CG  1 
ATOM 5488 C CD  . GLN C 3 267 ? 113.816 145.256 154.677 1.00 83.45  ? 267 GLN C CD  1 
ATOM 5489 O OE1 . GLN C 3 267 ? 113.392 145.813 153.666 1.00 81.72  ? 267 GLN C OE1 1 
ATOM 5490 N NE2 . GLN C 3 267 ? 115.019 144.704 154.737 1.00 85.66  ? 267 GLN C NE2 1 
ATOM 5491 N N   . ALA C 3 268 ? 110.678 141.118 155.428 1.00 78.97  ? 268 ALA C N   1 
ATOM 5492 C CA  . ALA C 3 268 ? 110.565 139.667 155.374 1.00 79.30  ? 268 ALA C CA  1 
ATOM 5493 C C   . ALA C 3 268 ? 110.326 139.192 153.949 1.00 73.13  ? 268 ALA C C   1 
ATOM 5494 O O   . ALA C 3 268 ? 110.900 138.184 153.519 1.00 76.29  ? 268 ALA C O   1 
ATOM 5495 C CB  . ALA C 3 268 ? 109.446 139.192 156.299 1.00 76.87  ? 268 ALA C CB  1 
ATOM 5496 N N   . ALA C 3 269 ? 109.495 139.920 153.198 1.00 67.47  ? 269 ALA C N   1 
ATOM 5497 C CA  . ALA C 3 269 ? 109.305 139.601 151.787 1.00 70.87  ? 269 ALA C CA  1 
ATOM 5498 C C   . ALA C 3 269 ? 110.597 139.779 150.999 1.00 68.93  ? 269 ALA C C   1 
ATOM 5499 O O   . ALA C 3 269 ? 110.913 138.965 150.120 1.00 70.19  ? 269 ALA C O   1 
ATOM 5500 C CB  . ALA C 3 269 ? 108.195 140.470 151.201 1.00 77.00  ? 269 ALA C CB  1 
ATOM 5501 N N   . LEU C 3 270 ? 111.356 140.836 151.307 1.00 69.11  ? 270 LEU C N   1 
ATOM 5502 C CA  . LEU C 3 270 ? 112.609 141.091 150.604 1.00 68.26  ? 270 LEU C CA  1 
ATOM 5503 C C   . LEU C 3 270 ? 113.623 139.982 150.830 1.00 69.71  ? 270 LEU C C   1 
ATOM 5504 O O   . LEU C 3 270 ? 114.261 139.525 149.877 1.00 72.93  ? 270 LEU C O   1 
ATOM 5505 C CB  . LEU C 3 270 ? 113.204 142.439 151.010 1.00 69.74  ? 270 LEU C CB  1 
ATOM 5506 C CG  . LEU C 3 270 ? 112.982 143.640 150.084 1.00 72.10  ? 270 LEU C CG  1 
ATOM 5507 C CD1 . LEU C 3 270 ? 111.528 144.031 149.930 1.00 73.69  ? 270 LEU C CD1 1 
ATOM 5508 C CD2 . LEU C 3 270 ? 113.813 144.824 150.554 1.00 76.70  ? 270 LEU C CD2 1 
ATOM 5509 N N   . LYS C 3 271 ? 113.786 139.513 152.067 1.00 66.91  ? 271 LYS C N   1 
ATOM 5510 C CA  . LYS C 3 271 ? 114.726 138.403 152.188 1.00 64.78  ? 271 LYS C CA  1 
ATOM 5511 C C   . LYS C 3 271 ? 114.158 137.043 151.834 1.00 63.90  ? 271 LYS C C   1 
ATOM 5512 O O   . LYS C 3 271 ? 114.945 136.125 151.584 1.00 67.79  ? 271 LYS C O   1 
ATOM 5513 C CB  . LYS C 3 271 ? 115.398 138.296 153.542 1.00 65.55  ? 271 LYS C CB  1 
ATOM 5514 C CG  . LYS C 3 271 ? 115.764 139.528 154.239 1.00 72.93  ? 271 LYS C CG  1 
ATOM 5515 C CD  . LYS C 3 271 ? 117.002 139.025 154.913 1.00 78.10  ? 271 LYS C CD  1 
ATOM 5516 C CE  . LYS C 3 271 ? 117.824 140.041 155.574 1.00 76.16  ? 271 LYS C CE  1 
ATOM 5517 N NZ  . LYS C 3 271 ? 118.527 139.300 156.644 1.00 69.84  ? 271 LYS C NZ  1 
ATOM 5518 N N   . LEU C 3 272 ? 112.842 136.866 151.777 1.00 62.33  ? 272 LEU C N   1 
ATOM 5519 C CA  . LEU C 3 272 ? 112.352 135.643 151.154 1.00 61.52  ? 272 LEU C CA  1 
ATOM 5520 C C   . LEU C 3 272 ? 112.709 135.630 149.673 1.00 61.96  ? 272 LEU C C   1 
ATOM 5521 O O   . LEU C 3 272 ? 113.161 134.606 149.143 1.00 64.06  ? 272 LEU C O   1 
ATOM 5522 C CB  . LEU C 3 272 ? 110.850 135.497 151.375 1.00 65.85  ? 272 LEU C CB  1 
ATOM 5523 C CG  . LEU C 3 272 ? 110.270 134.080 151.363 1.00 67.88  ? 272 LEU C CG  1 
ATOM 5524 C CD1 . LEU C 3 272 ? 111.283 133.044 151.835 1.00 70.39  ? 272 LEU C CD1 1 
ATOM 5525 C CD2 . LEU C 3 272 ? 109.002 134.021 152.207 1.00 65.45  ? 272 LEU C CD2 1 
ATOM 5526 N N   . PHE C 3 273 ? 112.583 136.786 149.011 1.00 62.04  ? 273 PHE C N   1 
ATOM 5527 C CA  . PHE C 3 273 ? 113.032 136.917 147.628 1.00 59.22  ? 273 PHE C CA  1 
ATOM 5528 C C   . PHE C 3 273 ? 114.542 136.712 147.525 1.00 62.57  ? 273 PHE C C   1 
ATOM 5529 O O   . PHE C 3 273 ? 115.025 136.089 146.576 1.00 68.00  ? 273 PHE C O   1 
ATOM 5530 C CB  . PHE C 3 273 ? 112.646 138.294 147.088 1.00 57.29  ? 273 PHE C CB  1 
ATOM 5531 C CG  . PHE C 3 273 ? 112.949 138.499 145.625 1.00 57.60  ? 273 PHE C CG  1 
ATOM 5532 C CD1 . PHE C 3 273 ? 112.953 137.442 144.734 1.00 57.39  ? 273 PHE C CD1 1 
ATOM 5533 C CD2 . PHE C 3 273 ? 113.282 139.752 145.154 1.00 61.96  ? 273 PHE C CD2 1 
ATOM 5534 C CE1 . PHE C 3 273 ? 113.246 137.639 143.410 1.00 58.71  ? 273 PHE C CE1 1 
ATOM 5535 C CE2 . PHE C 3 273 ? 113.570 139.957 143.823 1.00 63.10  ? 273 PHE C CE2 1 
ATOM 5536 C CZ  . PHE C 3 273 ? 113.555 138.896 142.950 1.00 61.07  ? 273 PHE C CZ  1 
ATOM 5537 N N   . ASP C 3 274 ? 115.298 137.245 148.489 1.00 63.03  ? 274 ASP C N   1 
ATOM 5538 C CA  . ASP C 3 274 ? 116.754 137.101 148.495 1.00 63.69  ? 274 ASP C CA  1 
ATOM 5539 C C   . ASP C 3 274 ? 117.172 135.642 148.610 1.00 60.42  ? 274 ASP C C   1 
ATOM 5540 O O   . ASP C 3 274 ? 118.082 135.185 147.906 1.00 62.15  ? 274 ASP C O   1 
ATOM 5541 C CB  . ASP C 3 274 ? 117.349 137.907 149.648 1.00 68.68  ? 274 ASP C CB  1 
ATOM 5542 C CG  . ASP C 3 274 ? 118.562 138.707 149.241 1.00 70.58  ? 274 ASP C CG  1 
ATOM 5543 O OD1 . ASP C 3 274 ? 119.561 138.092 148.818 1.00 68.99  ? 274 ASP C OD1 1 
ATOM 5544 O OD2 . ASP C 3 274 ? 118.525 139.950 149.359 1.00 70.17  ? 274 ASP C OD2 1 
ATOM 5545 N N   . SER C 3 275 ? 116.516 134.897 149.497 1.00 57.60  ? 275 SER C N   1 
ATOM 5546 C CA  . SER C 3 275 ? 116.836 133.490 149.670 1.00 56.23  ? 275 SER C CA  1 
ATOM 5547 C C   . SER C 3 275 ? 116.408 132.659 148.467 1.00 57.72  ? 275 SER C C   1 
ATOM 5548 O O   . SER C 3 275 ? 117.068 131.666 148.145 1.00 60.77  ? 275 SER C O   1 
ATOM 5549 C CB  . SER C 3 275 ? 116.185 132.968 150.946 1.00 61.70  ? 275 SER C CB  1 
ATOM 5550 O OG  . SER C 3 275 ? 116.314 133.905 152.001 1.00 63.46  ? 275 SER C OG  1 
ATOM 5551 N N   . ILE C 3 276 ? 115.308 133.028 147.804 1.00 58.42  ? 276 ILE C N   1 
ATOM 5552 C CA  . ILE C 3 276 ? 114.938 132.332 146.572 1.00 57.71  ? 276 ILE C CA  1 
ATOM 5553 C C   . ILE C 3 276 ? 115.948 132.624 145.467 1.00 59.41  ? 276 ILE C C   1 
ATOM 5554 O O   . ILE C 3 276 ? 116.372 131.717 144.739 1.00 63.50  ? 276 ILE C O   1 
ATOM 5555 C CB  . ILE C 3 276 ? 113.503 132.701 146.143 1.00 61.15  ? 276 ILE C CB  1 
ATOM 5556 C CG1 . ILE C 3 276 ? 112.461 132.226 147.161 1.00 61.57  ? 276 ILE C CG1 1 
ATOM 5557 C CG2 . ILE C 3 276 ? 113.169 132.125 144.778 1.00 66.54  ? 276 ILE C CG2 1 
ATOM 5558 C CD1 . ILE C 3 276 ? 112.754 130.895 147.811 1.00 61.27  ? 276 ILE C CD1 1 
ATOM 5559 N N   . TRP C 3 277 ? 116.365 133.885 145.341 1.00 56.99  ? 277 TRP C N   1 
ATOM 5560 C CA  . TRP C 3 277 ? 117.262 134.290 144.265 1.00 55.75  ? 277 TRP C CA  1 
ATOM 5561 C C   . TRP C 3 277 ? 118.650 133.686 144.422 1.00 59.22  ? 277 TRP C C   1 
ATOM 5562 O O   . TRP C 3 277 ? 119.212 133.156 143.458 1.00 63.75  ? 277 TRP C O   1 
ATOM 5563 C CB  . TRP C 3 277 ? 117.355 135.812 144.224 1.00 57.20  ? 277 TRP C CB  1 
ATOM 5564 C CG  . TRP C 3 277 ? 117.771 136.369 142.907 1.00 59.00  ? 277 TRP C CG  1 
ATOM 5565 C CD1 . TRP C 3 277 ? 118.973 136.927 142.601 1.00 62.92  ? 277 TRP C CD1 1 
ATOM 5566 C CD2 . TRP C 3 277 ? 116.984 136.437 141.719 1.00 57.70  ? 277 TRP C CD2 1 
ATOM 5567 N NE1 . TRP C 3 277 ? 118.987 137.334 141.293 1.00 63.63  ? 277 TRP C NE1 1 
ATOM 5568 C CE2 . TRP C 3 277 ? 117.774 137.043 140.729 1.00 61.13  ? 277 TRP C CE2 1 
ATOM 5569 C CE3 . TRP C 3 277 ? 115.688 136.041 141.395 1.00 59.72  ? 277 TRP C CE3 1 
ATOM 5570 C CZ2 . TRP C 3 277 ? 117.310 137.260 139.438 1.00 63.10  ? 277 TRP C CZ2 1 
ATOM 5571 C CZ3 . TRP C 3 277 ? 115.232 136.262 140.117 1.00 60.79  ? 277 TRP C CZ3 1 
ATOM 5572 C CH2 . TRP C 3 277 ? 116.038 136.864 139.154 1.00 62.98  ? 277 TRP C CH2 1 
ATOM 5573 N N   . ASN C 3 278 ? 119.215 133.745 145.621 1.00 58.44  ? 278 ASN C N   1 
ATOM 5574 C CA  . ASN C 3 278 ? 120.609 133.382 145.821 1.00 58.57  ? 278 ASN C CA  1 
ATOM 5575 C C   . ASN C 3 278 ? 120.799 131.914 146.171 1.00 64.66  ? 278 ASN C C   1 
ATOM 5576 O O   . ASN C 3 278 ? 121.926 131.506 146.466 1.00 68.76  ? 278 ASN C O   1 
ATOM 5577 C CB  . ASN C 3 278 ? 121.224 134.264 146.907 1.00 59.65  ? 278 ASN C CB  1 
ATOM 5578 C CG  . ASN C 3 278 ? 121.602 135.634 146.393 1.00 64.93  ? 278 ASN C CG  1 
ATOM 5579 O OD1 . ASN C 3 278 ? 122.333 135.758 145.414 1.00 68.36  ? 278 ASN C OD1 1 
ATOM 5580 N ND2 . ASN C 3 278 ? 121.104 136.672 147.050 1.00 66.42  ? 278 ASN C ND2 1 
ATOM 5581 N N   . ASN C 3 279 ? 119.735 131.118 146.159 1.00 64.71  ? 279 ASN C N   1 
ATOM 5582 C CA  . ASN C 3 279 ? 119.874 129.697 146.431 1.00 59.87  ? 279 ASN C CA  1 
ATOM 5583 C C   . ASN C 3 279 ? 120.543 128.999 145.257 1.00 62.30  ? 279 ASN C C   1 
ATOM 5584 O O   . ASN C 3 279 ? 120.438 129.428 144.106 1.00 67.02  ? 279 ASN C O   1 
ATOM 5585 C CB  . ASN C 3 279 ? 118.518 129.060 146.711 1.00 60.84  ? 279 ASN C CB  1 
ATOM 5586 C CG  . ASN C 3 279 ? 118.621 127.877 147.640 1.00 70.13  ? 279 ASN C CG  1 
ATOM 5587 O OD1 . ASN C 3 279 ? 119.718 127.456 147.999 1.00 73.62  ? 279 ASN C OD1 1 
ATOM 5588 N ND2 . ASN C 3 279 ? 117.480 127.332 148.039 1.00 73.67  ? 279 ASN C ND2 1 
ATOM 5589 N N   . LYS C 3 280 ? 121.234 127.907 145.559 1.00 63.00  ? 280 LYS C N   1 
ATOM 5590 C CA  . LYS C 3 280 ? 122.060 127.243 144.563 1.00 63.95  ? 280 LYS C CA  1 
ATOM 5591 C C   . LYS C 3 280 ? 121.291 126.246 143.710 1.00 64.73  ? 280 LYS C C   1 
ATOM 5592 O O   . LYS C 3 280 ? 121.888 125.636 142.818 1.00 65.67  ? 280 LYS C O   1 
ATOM 5593 C CB  . LYS C 3 280 ? 123.241 126.555 145.248 1.00 66.22  ? 280 LYS C CB  1 
ATOM 5594 C CG  . LYS C 3 280 ? 122.867 125.433 146.191 1.00 70.43  ? 280 LYS C CG  1 
ATOM 5595 C CD  . LYS C 3 280 ? 124.108 124.865 146.861 1.00 70.13  ? 280 LYS C CD  1 
ATOM 5596 C CE  . LYS C 3 280 ? 124.987 124.120 145.871 1.00 69.37  ? 280 LYS C CE  1 
ATOM 5597 N NZ  . LYS C 3 280 ? 126.416 124.126 146.285 1.00 72.19  ? 280 LYS C NZ  1 
ATOM 5598 N N   . TRP C 3 281 ? 119.995 126.058 143.953 1.00 64.37  ? 281 TRP C N   1 
ATOM 5599 C CA  . TRP C 3 281 ? 119.178 125.196 143.112 1.00 63.76  ? 281 TRP C CA  1 
ATOM 5600 C C   . TRP C 3 281 ? 118.029 125.916 142.431 1.00 63.05  ? 281 TRP C C   1 
ATOM 5601 O O   . TRP C 3 281 ? 117.395 125.330 141.548 1.00 64.78  ? 281 TRP C O   1 
ATOM 5602 C CB  . TRP C 3 281 ? 118.629 124.014 143.925 1.00 62.37  ? 281 TRP C CB  1 
ATOM 5603 C CG  . TRP C 3 281 ? 119.688 123.338 144.715 1.00 61.07  ? 281 TRP C CG  1 
ATOM 5604 C CD1 . TRP C 3 281 ? 119.814 123.315 146.068 1.00 59.90  ? 281 TRP C CD1 1 
ATOM 5605 C CD2 . TRP C 3 281 ? 120.811 122.624 144.194 1.00 64.23  ? 281 TRP C CD2 1 
ATOM 5606 N NE1 . TRP C 3 281 ? 120.933 122.608 146.425 1.00 60.87  ? 281 TRP C NE1 1 
ATOM 5607 C CE2 . TRP C 3 281 ? 121.564 122.177 145.290 1.00 63.59  ? 281 TRP C CE2 1 
ATOM 5608 C CE3 . TRP C 3 281 ? 121.248 122.312 142.903 1.00 65.64  ? 281 TRP C CE3 1 
ATOM 5609 C CZ2 . TRP C 3 281 ? 122.728 121.438 145.137 1.00 64.55  ? 281 TRP C CZ2 1 
ATOM 5610 C CZ3 . TRP C 3 281 ? 122.402 121.579 142.754 1.00 65.83  ? 281 TRP C CZ3 1 
ATOM 5611 C CH2 . TRP C 3 281 ? 123.131 121.151 143.863 1.00 66.21  ? 281 TRP C CH2 1 
ATOM 5612 N N   . LEU C 3 282 ? 117.748 127.157 142.803 1.00 61.63  ? 282 LEU C N   1 
ATOM 5613 C CA  . LEU C 3 282 ? 116.699 127.942 142.180 1.00 61.30  ? 282 LEU C CA  1 
ATOM 5614 C C   . LEU C 3 282 ? 117.246 128.939 141.171 1.00 65.27  ? 282 LEU C C   1 
ATOM 5615 O O   . LEU C 3 282 ? 116.527 129.862 140.776 1.00 66.55  ? 282 LEU C O   1 
ATOM 5616 C CB  . LEU C 3 282 ? 115.888 128.669 143.251 1.00 62.00  ? 282 LEU C CB  1 
ATOM 5617 C CG  . LEU C 3 282 ? 115.354 127.801 144.387 1.00 66.05  ? 282 LEU C CG  1 
ATOM 5618 C CD1 . LEU C 3 282 ? 114.548 128.639 145.359 1.00 66.86  ? 282 LEU C CD1 1 
ATOM 5619 C CD2 . LEU C 3 282 ? 114.512 126.672 143.837 1.00 64.60  ? 282 LEU C CD2 1 
ATOM 5620 N N   . ARG C 3 283 ? 118.506 128.787 140.760 1.00 65.61  ? 283 ARG C N   1 
ATOM 5621 C CA  . ARG C 3 283 ? 119.089 129.716 139.798 1.00 64.77  ? 283 ARG C CA  1 
ATOM 5622 C C   . ARG C 3 283 ? 118.504 129.513 138.408 1.00 62.12  ? 283 ARG C C   1 
ATOM 5623 O O   . ARG C 3 283 ? 118.352 130.474 137.647 1.00 64.54  ? 283 ARG C O   1 
ATOM 5624 C CB  . ARG C 3 283 ? 120.606 129.560 139.768 1.00 66.53  ? 283 ARG C CB  1 
ATOM 5625 C CG  . ARG C 3 283 ? 121.343 130.521 140.679 1.00 72.99  ? 283 ARG C CG  1 
ATOM 5626 C CD  . ARG C 3 283 ? 122.828 130.199 140.731 1.00 80.26  ? 283 ARG C CD  1 
ATOM 5627 N NE  . ARG C 3 283 ? 123.592 131.208 141.458 1.00 86.93  ? 283 ARG C NE  1 
ATOM 5628 C CZ  . ARG C 3 283 ? 123.672 131.284 142.780 1.00 83.15  ? 283 ARG C CZ  1 
ATOM 5629 N NH1 . ARG C 3 283 ? 123.051 130.417 143.563 1.00 79.11  ? 283 ARG C NH1 1 
ATOM 5630 N NH2 . ARG C 3 283 ? 124.400 132.252 143.331 1.00 84.17  ? 283 ARG C NH2 1 
ATOM 5631 N N   . ASP C 3 284 ? 118.187 128.270 138.053 1.00 61.53  ? 284 ASP C N   1 
ATOM 5632 C CA  . ASP C 3 284 ? 117.543 128.013 136.771 1.00 64.13  ? 284 ASP C CA  1 
ATOM 5633 C C   . ASP C 3 284 ? 116.119 128.550 136.754 1.00 66.00  ? 284 ASP C C   1 
ATOM 5634 O O   . ASP C 3 284 ? 115.689 129.155 135.766 1.00 67.39  ? 284 ASP C O   1 
ATOM 5635 C CB  . ASP C 3 284 ? 117.551 126.514 136.473 1.00 71.48  ? 284 ASP C CB  1 
ATOM 5636 C CG  . ASP C 3 284 ? 118.694 126.105 135.566 1.00 77.93  ? 284 ASP C CG  1 
ATOM 5637 O OD1 . ASP C 3 284 ? 119.565 126.953 135.288 1.00 81.70  ? 284 ASP C OD1 1 
ATOM 5638 O OD2 . ASP C 3 284 ? 118.721 124.934 135.133 1.00 77.20  ? 284 ASP C OD2 1 
ATOM 5639 N N   . THR C 3 285 ? 115.374 128.338 137.834 1.00 64.00  ? 285 THR C N   1 
ATOM 5640 C CA  . THR C 3 285 ? 113.987 128.769 137.875 1.00 60.38  ? 285 THR C CA  1 
ATOM 5641 C C   . THR C 3 285 ? 113.905 130.270 138.113 1.00 55.39  ? 285 THR C C   1 
ATOM 5642 O O   . THR C 3 285 ? 114.836 130.897 138.625 1.00 57.57  ? 285 THR C O   1 
ATOM 5643 C CB  . THR C 3 285 ? 113.211 127.999 138.950 1.00 63.57  ? 285 THR C CB  1 
ATOM 5644 O OG1 . THR C 3 285 ? 111.822 127.952 138.598 1.00 67.70  ? 285 THR C OG1 1 
ATOM 5645 C CG2 . THR C 3 285 ? 113.360 128.631 140.326 1.00 62.41  ? 285 THR C CG2 1 
ATOM 5646 N N   . SER C 3 286 ? 112.790 130.850 137.698 1.00 52.42  ? 286 SER C N   1 
ATOM 5647 C CA  . SER C 3 286 ? 112.574 132.280 137.801 1.00 55.70  ? 286 SER C CA  1 
ATOM 5648 C C   . SER C 3 286 ? 111.371 132.561 138.682 1.00 58.39  ? 286 SER C C   1 
ATOM 5649 O O   . SER C 3 286 ? 110.677 131.653 139.145 1.00 65.70  ? 286 SER C O   1 
ATOM 5650 C CB  . SER C 3 286 ? 112.376 132.907 136.424 1.00 59.48  ? 286 SER C CB  1 
ATOM 5651 O OG  . SER C 3 286 ? 111.544 134.050 136.505 1.00 64.44  ? 286 SER C OG  1 
ATOM 5652 N N   . VAL C 3 287 ? 111.132 133.843 138.915 1.00 53.98  ? 287 VAL C N   1 
ATOM 5653 C CA  . VAL C 3 287 ? 110.091 134.275 139.830 1.00 54.33  ? 287 VAL C CA  1 
ATOM 5654 C C   . VAL C 3 287 ? 109.202 135.292 139.129 1.00 55.21  ? 287 VAL C C   1 
ATOM 5655 O O   . VAL C 3 287 ? 109.670 136.154 138.379 1.00 60.29  ? 287 VAL C O   1 
ATOM 5656 C CB  . VAL C 3 287 ? 110.720 134.842 141.123 1.00 55.46  ? 287 VAL C CB  1 
ATOM 5657 C CG1 . VAL C 3 287 ? 111.822 135.791 140.776 1.00 58.00  ? 287 VAL C CG1 1 
ATOM 5658 C CG2 . VAL C 3 287 ? 109.698 135.509 142.033 1.00 57.81  ? 287 VAL C CG2 1 
ATOM 5659 N N   . ILE C 3 288 ? 107.903 135.167 139.362 1.00 52.49  ? 288 ILE C N   1 
ATOM 5660 C CA  . ILE C 3 288 ? 106.926 136.163 138.961 1.00 52.77  ? 288 ILE C CA  1 
ATOM 5661 C C   . ILE C 3 288 ? 106.473 136.859 140.230 1.00 56.67  ? 288 ILE C C   1 
ATOM 5662 O O   . ILE C 3 288 ? 105.984 136.208 141.162 1.00 62.38  ? 288 ILE C O   1 
ATOM 5663 C CB  . ILE C 3 288 ? 105.738 135.532 138.230 1.00 51.86  ? 288 ILE C CB  1 
ATOM 5664 C CG1 . ILE C 3 288 ? 106.204 134.748 137.013 1.00 53.69  ? 288 ILE C CG1 1 
ATOM 5665 C CG2 . ILE C 3 288 ? 104.767 136.592 137.828 1.00 55.96  ? 288 ILE C CG2 1 
ATOM 5666 C CD1 . ILE C 3 288 ? 105.093 133.963 136.371 1.00 61.42  ? 288 ILE C CD1 1 
ATOM 5667 N N   . LEU C 3 289 ? 106.635 138.171 140.272 1.00 55.36  ? 289 LEU C N   1 
ATOM 5668 C CA  . LEU C 3 289 ? 106.411 138.947 141.479 1.00 57.73  ? 289 LEU C CA  1 
ATOM 5669 C C   . LEU C 3 289 ? 105.078 139.668 141.360 1.00 61.08  ? 289 LEU C C   1 
ATOM 5670 O O   . LEU C 3 289 ? 104.786 140.278 140.327 1.00 68.04  ? 289 LEU C O   1 
ATOM 5671 C CB  . LEU C 3 289 ? 107.553 139.940 141.695 1.00 59.91  ? 289 LEU C CB  1 
ATOM 5672 C CG  . LEU C 3 289 ? 107.953 140.368 143.107 1.00 64.24  ? 289 LEU C CG  1 
ATOM 5673 C CD1 . LEU C 3 289 ? 109.254 141.121 143.021 1.00 65.56  ? 289 LEU C CD1 1 
ATOM 5674 C CD2 . LEU C 3 289 ? 106.915 141.208 143.827 1.00 66.67  ? 289 LEU C CD2 1 
ATOM 5675 N N   . PHE C 3 290 ? 104.274 139.589 142.413 1.00 60.06  ? 290 PHE C N   1 
ATOM 5676 C CA  . PHE C 3 290 ? 102.993 140.275 142.488 1.00 62.41  ? 290 PHE C CA  1 
ATOM 5677 C C   . PHE C 3 290 ? 103.028 141.223 143.675 1.00 69.81  ? 290 PHE C C   1 
ATOM 5678 O O   . PHE C 3 290 ? 103.358 140.809 144.791 1.00 76.11  ? 290 PHE C O   1 
ATOM 5679 C CB  . PHE C 3 290 ? 101.842 139.282 142.641 1.00 65.61  ? 290 PHE C CB  1 
ATOM 5680 C CG  . PHE C 3 290 ? 101.512 138.537 141.388 1.00 63.88  ? 290 PHE C CG  1 
ATOM 5681 C CD1 . PHE C 3 290 ? 102.233 137.423 141.012 1.00 61.31  ? 290 PHE C CD1 1 
ATOM 5682 C CD2 . PHE C 3 290 ? 100.471 138.943 140.593 1.00 62.89  ? 290 PHE C CD2 1 
ATOM 5683 C CE1 . PHE C 3 290 ? 101.912 136.740 139.859 1.00 57.64  ? 290 PHE C CE1 1 
ATOM 5684 C CE2 . PHE C 3 290 ? 100.153 138.269 139.439 1.00 64.55  ? 290 PHE C CE2 1 
ATOM 5685 C CZ  . PHE C 3 290 ? 100.876 137.167 139.072 1.00 57.55  ? 290 PHE C CZ  1 
ATOM 5686 N N   . LEU C 3 291 ? 102.691 142.489 143.437 1.00 72.51  ? 291 LEU C N   1 
ATOM 5687 C CA  . LEU C 3 291 ? 102.586 143.467 144.518 1.00 78.12  ? 291 LEU C CA  1 
ATOM 5688 C C   . LEU C 3 291 ? 101.110 143.624 144.868 1.00 86.94  ? 291 LEU C C   1 
ATOM 5689 O O   . LEU C 3 291 ? 100.442 144.591 144.500 1.00 90.31  ? 291 LEU C O   1 
ATOM 5690 C CB  . LEU C 3 291 ? 103.221 144.795 144.129 1.00 78.51  ? 291 LEU C CB  1 
ATOM 5691 C CG  . LEU C 3 291 ? 104.742 144.914 143.958 1.00 79.55  ? 291 LEU C CG  1 
ATOM 5692 C CD1 . LEU C 3 291 ? 105.462 144.394 145.195 1.00 75.96  ? 291 LEU C CD1 1 
ATOM 5693 C CD2 . LEU C 3 291 ? 105.301 144.317 142.663 1.00 73.26  ? 291 LEU C CD2 1 
ATOM 5694 N N   . ASN C 3 292 ? 100.604 142.644 145.608 1.00 90.54  ? 292 ASN C N   1 
ATOM 5695 C CA  . ASN C 3 292 ? 99.188  142.559 145.918 1.00 92.53  ? 292 ASN C CA  1 
ATOM 5696 C C   . ASN C 3 292 ? 98.888  143.578 147.022 1.00 94.18  ? 292 ASN C C   1 
ATOM 5697 O O   . ASN C 3 292 ? 99.790  144.078 147.700 1.00 96.46  ? 292 ASN C O   1 
ATOM 5698 C CB  . ASN C 3 292 ? 98.872  141.075 146.251 1.00 93.63  ? 292 ASN C CB  1 
ATOM 5699 C CG  . ASN C 3 292 ? 97.538  140.800 147.011 1.00 101.34 ? 292 ASN C CG  1 
ATOM 5700 O OD1 . ASN C 3 292 ? 96.862  141.661 147.561 1.00 99.42  ? 292 ASN C OD1 1 
ATOM 5701 N ND2 . ASN C 3 292 ? 97.174  139.523 147.020 1.00 105.97 ? 292 ASN C ND2 1 
ATOM 5702 N N   . LYS C 3 293 ? 97.596  143.899 147.166 1.00 94.88  ? 293 LYS C N   1 
ATOM 5703 C CA  . LYS C 3 293 ? 97.075  144.821 148.184 1.00 102.92 ? 293 LYS C CA  1 
ATOM 5704 C C   . LYS C 3 293 ? 97.680  146.215 148.045 1.00 102.86 ? 293 LYS C C   1 
ATOM 5705 O O   . LYS C 3 293 ? 98.224  146.782 148.994 1.00 107.33 ? 293 LYS C O   1 
ATOM 5706 C CB  . LYS C 3 293 ? 97.272  144.271 149.602 1.00 104.70 ? 293 LYS C CB  1 
ATOM 5707 C CG  . LYS C 3 293 ? 96.172  144.678 150.571 1.00 108.79 ? 293 LYS C CG  1 
ATOM 5708 C CD  . LYS C 3 293 ? 96.723  144.981 151.955 1.00 111.28 ? 293 LYS C CD  1 
ATOM 5709 C CE  . LYS C 3 293 ? 97.454  143.787 152.543 1.00 112.23 ? 293 LYS C CE  1 
ATOM 5710 N NZ  . LYS C 3 293 ? 96.513  142.688 152.893 1.00 117.58 ? 293 LYS C NZ  1 
ATOM 5711 N N   . GLN C 3 294 ? 97.587  146.765 146.838 1.00 98.68  ? 294 GLN C N   1 
ATOM 5712 C CA  . GLN C 3 294 ? 97.958  148.154 146.622 1.00 100.89 ? 294 GLN C CA  1 
ATOM 5713 C C   . GLN C 3 294 ? 96.785  149.111 146.785 1.00 107.76 ? 294 GLN C C   1 
ATOM 5714 O O   . GLN C 3 294 ? 96.994  150.328 146.750 1.00 108.58 ? 294 GLN C O   1 
ATOM 5715 C CB  . GLN C 3 294 ? 98.578  148.325 145.238 1.00 98.92  ? 294 GLN C CB  1 
ATOM 5716 C CG  . GLN C 3 294 ? 98.099  147.315 144.225 1.00 99.30  ? 294 GLN C CG  1 
ATOM 5717 C CD  . GLN C 3 294 ? 98.980  147.283 143.001 1.00 98.37  ? 294 GLN C CD  1 
ATOM 5718 O OE1 . GLN C 3 294 ? 100.204 147.262 143.112 1.00 98.82  ? 294 GLN C OE1 1 
ATOM 5719 N NE2 . GLN C 3 294 ? 98.364  147.270 141.824 1.00 96.86  ? 294 GLN C NE2 1 
ATOM 5720 N N   . ASP C 3 295 ? 95.563  148.599 146.956 1.00 112.19 ? 295 ASP C N   1 
ATOM 5721 C CA  . ASP C 3 295 ? 94.430  149.479 147.226 1.00 116.42 ? 295 ASP C CA  1 
ATOM 5722 C C   . ASP C 3 295 ? 94.510  150.072 148.627 1.00 118.64 ? 295 ASP C C   1 
ATOM 5723 O O   . ASP C 3 295 ? 94.259  151.267 148.817 1.00 121.04 ? 295 ASP C O   1 
ATOM 5724 C CB  . ASP C 3 295 ? 93.112  148.729 147.020 1.00 120.11 ? 295 ASP C CB  1 
ATOM 5725 C CG  . ASP C 3 295 ? 93.078  147.372 147.716 1.00 123.01 ? 295 ASP C CG  1 
ATOM 5726 O OD1 . ASP C 3 295 ? 93.929  147.102 148.591 1.00 120.79 ? 295 ASP C OD1 1 
ATOM 5727 O OD2 . ASP C 3 295 ? 92.184  146.566 147.384 1.00 126.75 ? 295 ASP C OD2 1 
ATOM 5728 N N   . LEU C 3 296 ? 94.856  149.252 149.619 1.00 117.16 ? 296 LEU C N   1 
ATOM 5729 C CA  . LEU C 3 296 ? 95.078  149.757 150.967 1.00 117.91 ? 296 LEU C CA  1 
ATOM 5730 C C   . LEU C 3 296 ? 96.377  150.545 151.066 1.00 118.11 ? 296 LEU C C   1 
ATOM 5731 O O   . LEU C 3 296 ? 96.510  151.388 151.961 1.00 122.01 ? 296 LEU C O   1 
ATOM 5732 C CB  . LEU C 3 296 ? 95.063  148.590 151.962 1.00 117.54 ? 296 LEU C CB  1 
ATOM 5733 C CG  . LEU C 3 296 ? 95.050  148.852 153.472 1.00 117.67 ? 296 LEU C CG  1 
ATOM 5734 C CD1 . LEU C 3 296 ? 94.101  147.885 154.159 1.00 110.67 ? 296 LEU C CD1 1 
ATOM 5735 C CD2 . LEU C 3 296 ? 96.440  148.721 154.070 1.00 118.15 ? 296 LEU C CD2 1 
ATOM 5736 N N   . LEU C 3 297 ? 97.321  150.297 150.153 1.00 113.13 ? 297 LEU C N   1 
ATOM 5737 C CA  . LEU C 3 297 ? 98.536  151.103 150.071 1.00 113.40 ? 297 LEU C CA  1 
ATOM 5738 C C   . LEU C 3 297 ? 98.201  152.557 149.758 1.00 117.44 ? 297 LEU C C   1 
ATOM 5739 O O   . LEU C 3 297 ? 98.812  153.477 150.311 1.00 119.93 ? 297 LEU C O   1 
ATOM 5740 C CB  . LEU C 3 297 ? 99.467  150.520 149.006 1.00 111.01 ? 297 LEU C CB  1 
ATOM 5741 C CG  . LEU C 3 297 ? 100.822 151.131 148.618 1.00 109.26 ? 297 LEU C CG  1 
ATOM 5742 C CD1 . LEU C 3 297 ? 101.572 151.744 149.795 1.00 110.23 ? 297 LEU C CD1 1 
ATOM 5743 C CD2 . LEU C 3 297 ? 101.687 150.096 147.908 1.00 103.84 ? 297 LEU C CD2 1 
ATOM 5744 N N   . ALA C 3 298 ? 97.224  152.778 148.873 1.00 118.19 ? 298 ALA C N   1 
ATOM 5745 C CA  . ALA C 3 298 ? 96.811  154.138 148.533 1.00 120.11 ? 298 ALA C CA  1 
ATOM 5746 C C   . ALA C 3 298 ? 96.205  154.856 149.732 1.00 124.21 ? 298 ALA C C   1 
ATOM 5747 O O   . ALA C 3 298 ? 96.504  156.031 149.977 1.00 124.73 ? 298 ALA C O   1 
ATOM 5748 C CB  . ALA C 3 298 ? 95.822  154.109 147.368 1.00 116.36 ? 298 ALA C CB  1 
ATOM 5749 N N   . GLU C 3 299 ? 95.362  154.160 150.501 1.00 123.87 ? 299 GLU C N   1 
ATOM 5750 C CA  . GLU C 3 299 ? 94.770  154.761 151.692 1.00 123.24 ? 299 GLU C CA  1 
ATOM 5751 C C   . GLU C 3 299 ? 95.820  155.029 152.764 1.00 123.64 ? 299 GLU C C   1 
ATOM 5752 O O   . GLU C 3 299 ? 95.752  156.046 153.465 1.00 125.34 ? 299 GLU C O   1 
ATOM 5753 C CB  . GLU C 3 299 ? 93.662  153.860 152.237 1.00 122.87 ? 299 GLU C CB  1 
ATOM 5754 C CG  . GLU C 3 299 ? 92.316  154.057 151.561 1.00 124.96 ? 299 GLU C CG  1 
ATOM 5755 C CD  . GLU C 3 299 ? 92.118  153.132 150.376 1.00 126.84 ? 299 GLU C CD  1 
ATOM 5756 O OE1 . GLU C 3 299 ? 91.966  151.912 150.592 1.00 127.90 ? 299 GLU C OE1 1 
ATOM 5757 O OE2 . GLU C 3 299 ? 92.113  153.626 149.229 1.00 126.56 ? 299 GLU C OE2 1 
ATOM 5758 N N   . LYS C 3 300 ? 96.799  154.130 152.906 1.00 121.34 ? 300 LYS C N   1 
ATOM 5759 C CA  . LYS C 3 300 ? 97.861  154.341 153.885 1.00 120.82 ? 300 LYS C CA  1 
ATOM 5760 C C   . LYS C 3 300 ? 98.763  155.503 153.487 1.00 120.06 ? 300 LYS C C   1 
ATOM 5761 O O   . LYS C 3 300 ? 99.243  156.245 154.352 1.00 122.30 ? 300 LYS C O   1 
ATOM 5762 C CB  . LYS C 3 300 ? 98.678  153.062 154.059 1.00 122.10 ? 300 LYS C CB  1 
ATOM 5763 C CG  . LYS C 3 300 ? 97.994  151.998 154.897 1.00 124.52 ? 300 LYS C CG  1 
ATOM 5764 C CD  . LYS C 3 300 ? 97.903  152.413 156.356 1.00 123.03 ? 300 LYS C CD  1 
ATOM 5765 C CE  . LYS C 3 300 ? 97.753  151.203 157.264 1.00 121.11 ? 300 LYS C CE  1 
ATOM 5766 N NZ  . LYS C 3 300 ? 98.868  150.232 157.084 1.00 123.08 ? 300 LYS C NZ  1 
ATOM 5767 N N   . VAL C 3 301 ? 99.017  155.667 152.188 1.00 118.66 ? 301 VAL C N   1 
ATOM 5768 C CA  . VAL C 3 301 ? 99.791  156.810 151.716 1.00 122.84 ? 301 VAL C CA  1 
ATOM 5769 C C   . VAL C 3 301 ? 99.011  158.104 151.926 1.00 125.84 ? 301 VAL C C   1 
ATOM 5770 O O   . VAL C 3 301 ? 99.568  159.117 152.370 1.00 128.14 ? 301 VAL C O   1 
ATOM 5771 C CB  . VAL C 3 301 ? 100.191 156.602 150.242 1.00 119.25 ? 301 VAL C CB  1 
ATOM 5772 C CG1 . VAL C 3 301 ? 100.571 157.916 149.570 1.00 115.44 ? 301 VAL C CG1 1 
ATOM 5773 C CG2 . VAL C 3 301 ? 101.342 155.612 150.146 1.00 116.51 ? 301 VAL C CG2 1 
ATOM 5774 N N   . LEU C 3 302 ? 97.703  158.079 151.648 1.00 124.89 ? 302 LEU C N   1 
ATOM 5775 C CA  . LEU C 3 302 ? 96.873  159.268 151.818 1.00 127.38 ? 302 LEU C CA  1 
ATOM 5776 C C   . LEU C 3 302 ? 96.736  159.665 153.283 1.00 128.40 ? 302 LEU C C   1 
ATOM 5777 O O   . LEU C 3 302 ? 96.629  160.859 153.590 1.00 129.10 ? 302 LEU C O   1 
ATOM 5778 C CB  . LEU C 3 302 ? 95.494  159.031 151.198 1.00 129.46 ? 302 LEU C CB  1 
ATOM 5779 C CG  . LEU C 3 302 ? 94.521  160.210 151.140 1.00 130.18 ? 302 LEU C CG  1 
ATOM 5780 C CD1 . LEU C 3 302 ? 95.091  161.338 150.295 1.00 125.67 ? 302 LEU C CD1 1 
ATOM 5781 C CD2 . LEU C 3 302 ? 93.168  159.765 150.606 1.00 125.88 ? 302 LEU C CD2 1 
ATOM 5782 N N   . ALA C 3 303 ? 96.733  158.689 154.196 1.00 128.77 ? 303 ALA C N   1 
ATOM 5783 C CA  . ALA C 3 303 ? 96.649  159.004 155.619 1.00 128.64 ? 303 ALA C CA  1 
ATOM 5784 C C   . ALA C 3 303 ? 97.910  159.711 156.106 1.00 127.44 ? 303 ALA C C   1 
ATOM 5785 O O   . ALA C 3 303 ? 97.835  160.765 156.747 1.00 127.56 ? 303 ALA C O   1 
ATOM 5786 C CB  . ALA C 3 303 ? 96.400  157.729 156.424 1.00 126.58 ? 303 ALA C CB  1 
ATOM 5787 N N   . GLY C 3 304 ? 99.079  159.147 155.809 1.00 125.28 ? 304 GLY C N   1 
ATOM 5788 C CA  . GLY C 3 304 ? 100.338 159.757 156.178 1.00 126.23 ? 304 GLY C CA  1 
ATOM 5789 C C   . GLY C 3 304 ? 100.763 159.563 157.617 1.00 130.11 ? 304 GLY C C   1 
ATOM 5790 O O   . GLY C 3 304 ? 101.821 160.077 158.003 1.00 126.60 ? 304 GLY C O   1 
ATOM 5791 N N   . LYS C 3 305 ? 99.983  158.845 158.426 1.00 134.41 ? 305 LYS C N   1 
ATOM 5792 C CA  . LYS C 3 305 ? 100.345 158.599 159.816 1.00 134.85 ? 305 LYS C CA  1 
ATOM 5793 C C   . LYS C 3 305 ? 101.221 157.367 159.995 1.00 136.32 ? 305 LYS C C   1 
ATOM 5794 O O   . LYS C 3 305 ? 101.819 157.198 161.063 1.00 136.98 ? 305 LYS C O   1 
ATOM 5795 C CB  . LYS C 3 305 ? 99.084  158.451 160.673 1.00 128.98 ? 305 LYS C CB  1 
ATOM 5796 N N   . SER C 3 306 ? 101.310 156.512 158.980 1.00 136.03 ? 306 SER C N   1 
ATOM 5797 C CA  . SER C 3 306 ? 102.122 155.299 158.995 1.00 130.77 ? 306 SER C CA  1 
ATOM 5798 C C   . SER C 3 306 ? 103.035 155.277 157.778 1.00 126.17 ? 306 SER C C   1 
ATOM 5799 O O   . SER C 3 306 ? 103.090 154.304 157.023 1.00 124.57 ? 306 SER C O   1 
ATOM 5800 C CB  . SER C 3 306 ? 101.243 154.052 159.041 1.00 129.67 ? 306 SER C CB  1 
ATOM 5801 O OG  . SER C 3 306 ? 100.514 153.899 157.836 1.00 125.13 ? 306 SER C OG  1 
ATOM 5802 N N   . LYS C 3 307 ? 103.746 156.383 157.571 1.00 122.31 ? 307 LYS C N   1 
ATOM 5803 C CA  . LYS C 3 307 ? 104.494 156.608 156.342 1.00 117.61 ? 307 LYS C CA  1 
ATOM 5804 C C   . LYS C 3 307 ? 105.667 155.644 156.207 1.00 113.70 ? 307 LYS C C   1 
ATOM 5805 O O   . LYS C 3 307 ? 106.213 155.144 157.193 1.00 115.73 ? 307 LYS C O   1 
ATOM 5806 C CB  . LYS C 3 307 ? 105.002 158.049 156.290 1.00 113.48 ? 307 LYS C CB  1 
ATOM 5807 C CG  . LYS C 3 307 ? 105.051 158.644 154.892 1.00 111.28 ? 307 LYS C CG  1 
ATOM 5808 C CD  . LYS C 3 307 ? 105.699 160.019 154.900 1.00 110.49 ? 307 LYS C CD  1 
ATOM 5809 C CE  . LYS C 3 307 ? 105.925 160.532 153.487 1.00 99.82  ? 307 LYS C CE  1 
ATOM 5810 N NZ  . LYS C 3 307 ? 106.585 161.866 153.479 1.00 95.69  ? 307 LYS C NZ  1 
ATOM 5811 N N   . ILE C 3 308 ? 106.042 155.377 154.954 1.00 109.53 ? 308 ILE C N   1 
ATOM 5812 C CA  . ILE C 3 308 ? 107.189 154.529 154.661 1.00 107.66 ? 308 ILE C CA  1 
ATOM 5813 C C   . ILE C 3 308 ? 108.492 155.265 154.962 1.00 108.36 ? 308 ILE C C   1 
ATOM 5814 O O   . ILE C 3 308 ? 109.539 154.628 155.135 1.00 108.68 ? 308 ILE C O   1 
ATOM 5815 C CB  . ILE C 3 308 ? 107.083 154.056 153.194 1.00 105.27 ? 308 ILE C CB  1 
ATOM 5816 C CG1 . ILE C 3 308 ? 108.158 153.028 152.829 1.00 105.02 ? 308 ILE C CG1 1 
ATOM 5817 C CG2 . ILE C 3 308 ? 107.139 155.244 152.245 1.00 103.76 ? 308 ILE C CG2 1 
ATOM 5818 C CD1 . ILE C 3 308 ? 107.642 151.873 152.004 1.00 102.62 ? 308 ILE C CD1 1 
ATOM 5819 N N   . GLU C 3 309 ? 108.436 156.596 155.079 1.00 108.21 ? 309 GLU C N   1 
ATOM 5820 C CA  . GLU C 3 309 ? 109.633 157.395 155.332 1.00 110.46 ? 309 GLU C CA  1 
ATOM 5821 C C   . GLU C 3 309 ? 110.253 157.068 156.686 1.00 112.63 ? 309 GLU C C   1 
ATOM 5822 O O   . GLU C 3 309 ? 111.481 156.985 156.810 1.00 111.49 ? 309 GLU C O   1 
ATOM 5823 C CB  . GLU C 3 309 ? 109.285 158.882 155.240 1.00 113.66 ? 309 GLU C CB  1 
ATOM 5824 C CG  . GLU C 3 309 ? 110.358 159.830 155.756 1.00 119.29 ? 309 GLU C CG  1 
ATOM 5825 C CD  . GLU C 3 309 ? 111.328 160.265 154.675 1.00 118.14 ? 309 GLU C CD  1 
ATOM 5826 O OE1 . GLU C 3 309 ? 111.178 159.814 153.520 1.00 114.88 ? 309 GLU C OE1 1 
ATOM 5827 O OE2 . GLU C 3 309 ? 112.240 161.061 154.981 1.00 118.35 ? 309 GLU C OE2 1 
ATOM 5828 N N   . ASP C 3 310 ? 109.424 156.847 157.708 1.00 115.33 ? 310 ASP C N   1 
ATOM 5829 C CA  . ASP C 3 310 ? 109.960 156.521 159.024 1.00 116.97 ? 310 ASP C CA  1 
ATOM 5830 C C   . ASP C 3 310 ? 110.444 155.080 159.130 1.00 109.43 ? 310 ASP C C   1 
ATOM 5831 O O   . ASP C 3 310 ? 111.074 154.734 160.135 1.00 109.57 ? 310 ASP C O   1 
ATOM 5832 C CB  . ASP C 3 310 ? 108.918 156.797 160.112 1.00 122.61 ? 310 ASP C CB  1 
ATOM 5833 C CG  . ASP C 3 310 ? 107.557 156.225 159.779 1.00 125.42 ? 310 ASP C CG  1 
ATOM 5834 O OD1 . ASP C 3 310 ? 107.377 154.996 159.911 1.00 121.12 ? 310 ASP C OD1 1 
ATOM 5835 O OD2 . ASP C 3 310 ? 106.663 157.007 159.391 1.00 127.85 ? 310 ASP C OD2 1 
ATOM 5836 N N   . TYR C 3 311 ? 110.172 154.235 158.136 1.00 103.70 ? 311 TYR C N   1 
ATOM 5837 C CA  . TYR C 3 311 ? 110.681 152.870 158.131 1.00 99.88  ? 311 TYR C CA  1 
ATOM 5838 C C   . TYR C 3 311 ? 111.602 152.634 156.938 1.00 99.08  ? 311 TYR C C   1 
ATOM 5839 O O   . TYR C 3 311 ? 112.019 151.498 156.693 1.00 93.67  ? 311 TYR C O   1 
ATOM 5840 C CB  . TYR C 3 311 ? 109.514 151.875 158.133 1.00 98.40  ? 311 TYR C CB  1 
ATOM 5841 C CG  . TYR C 3 311 ? 109.717 150.634 158.988 1.00 100.46 ? 311 TYR C CG  1 
ATOM 5842 C CD1 . TYR C 3 311 ? 108.952 150.440 160.131 1.00 103.89 ? 311 TYR C CD1 1 
ATOM 5843 C CD2 . TYR C 3 311 ? 110.651 149.662 158.661 1.00 101.22 ? 311 TYR C CD2 1 
ATOM 5844 C CE1 . TYR C 3 311 ? 109.118 149.318 160.923 1.00 104.90 ? 311 TYR C CE1 1 
ATOM 5845 C CE2 . TYR C 3 311 ? 110.830 148.543 159.448 1.00 103.70 ? 311 TYR C CE2 1 
ATOM 5846 C CZ  . TYR C 3 311 ? 110.058 148.372 160.575 1.00 105.15 ? 311 TYR C CZ  1 
ATOM 5847 O OH  . TYR C 3 311 ? 110.229 147.253 161.357 1.00 105.99 ? 311 TYR C OH  1 
ATOM 5848 N N   . PHE C 3 312 ? 111.934 153.678 156.188 1.00 102.80 ? 312 PHE C N   1 
ATOM 5849 C CA  . PHE C 3 312 ? 112.866 153.544 155.076 1.00 101.08 ? 312 PHE C CA  1 
ATOM 5850 C C   . PHE C 3 312 ? 113.595 154.860 154.846 1.00 99.62  ? 312 PHE C C   1 
ATOM 5851 O O   . PHE C 3 312 ? 112.974 155.853 154.446 1.00 103.16 ? 312 PHE C O   1 
ATOM 5852 C CB  . PHE C 3 312 ? 112.137 153.110 153.804 1.00 101.65 ? 312 PHE C CB  1 
ATOM 5853 C CG  . PHE C 3 312 ? 112.156 151.628 153.568 1.00 99.66  ? 312 PHE C CG  1 
ATOM 5854 C CD1 . PHE C 3 312 ? 113.335 150.981 153.244 1.00 98.48  ? 312 PHE C CD1 1 
ATOM 5855 C CD2 . PHE C 3 312 ? 110.993 150.883 153.662 1.00 97.15  ? 312 PHE C CD2 1 
ATOM 5856 C CE1 . PHE C 3 312 ? 113.354 149.618 153.022 1.00 96.58  ? 312 PHE C CE1 1 
ATOM 5857 C CE2 . PHE C 3 312 ? 111.005 149.522 153.439 1.00 91.73  ? 312 PHE C CE2 1 
ATOM 5858 C CZ  . PHE C 3 312 ? 112.186 148.889 153.119 1.00 93.45  ? 312 PHE C CZ  1 
ATOM 5859 N N   . PRO C 3 313 ? 114.908 154.914 155.086 1.00 96.57  ? 313 PRO C N   1 
ATOM 5860 C CA  . PRO C 3 313 ? 115.636 156.170 154.871 1.00 99.03  ? 313 PRO C CA  1 
ATOM 5861 C C   . PRO C 3 313 ? 115.928 156.462 153.414 1.00 104.32 ? 313 PRO C C   1 
ATOM 5862 O O   . PRO C 3 313 ? 116.243 157.614 153.084 1.00 109.64 ? 313 PRO C O   1 
ATOM 5863 C CB  . PRO C 3 313 ? 116.933 155.961 155.661 1.00 99.90  ? 313 PRO C CB  1 
ATOM 5864 C CG  . PRO C 3 313 ? 117.150 154.487 155.625 1.00 99.43  ? 313 PRO C CG  1 
ATOM 5865 C CD  . PRO C 3 313 ? 115.797 153.822 155.516 1.00 98.39  ? 313 PRO C CD  1 
ATOM 5866 N N   . GLU C 3 314 ? 115.835 155.466 152.533 1.00 101.67 ? 314 GLU C N   1 
ATOM 5867 C CA  . GLU C 3 314 ? 116.064 155.695 151.114 1.00 103.03 ? 314 GLU C CA  1 
ATOM 5868 C C   . GLU C 3 314 ? 114.906 156.415 150.442 1.00 102.36 ? 314 GLU C C   1 
ATOM 5869 O O   . GLU C 3 314 ? 115.082 156.946 149.341 1.00 104.57 ? 314 GLU C O   1 
ATOM 5870 C CB  . GLU C 3 314 ? 116.322 154.365 150.401 1.00 105.39 ? 314 GLU C CB  1 
ATOM 5871 C CG  . GLU C 3 314 ? 117.769 153.851 150.412 1.00 114.30 ? 314 GLU C CG  1 
ATOM 5872 C CD  . GLU C 3 314 ? 118.826 154.917 150.682 1.00 121.07 ? 314 GLU C CD  1 
ATOM 5873 O OE1 . GLU C 3 314 ? 118.985 155.848 149.860 1.00 120.41 ? 314 GLU C OE1 1 
ATOM 5874 O OE2 . GLU C 3 314 ? 119.501 154.822 151.729 1.00 121.18 ? 314 GLU C OE2 1 
ATOM 5875 N N   . PHE C 3 315 ? 113.732 156.446 151.075 1.00 101.57 ? 315 PHE C N   1 
ATOM 5876 C CA  . PHE C 3 315 ? 112.564 157.068 150.465 1.00 101.50 ? 315 PHE C CA  1 
ATOM 5877 C C   . PHE C 3 315 ? 112.676 158.585 150.392 1.00 105.23 ? 315 PHE C C   1 
ATOM 5878 O O   . PHE C 3 315 ? 112.003 159.201 149.559 1.00 107.12 ? 315 PHE C O   1 
ATOM 5879 C CB  . PHE C 3 315 ? 111.301 156.678 151.233 1.00 99.96  ? 315 PHE C CB  1 
ATOM 5880 C CG  . PHE C 3 315 ? 110.030 157.046 150.530 1.00 97.12  ? 315 PHE C CG  1 
ATOM 5881 C CD1 . PHE C 3 315 ? 109.642 156.382 149.383 1.00 90.81  ? 315 PHE C CD1 1 
ATOM 5882 C CD2 . PHE C 3 315 ? 109.226 158.064 151.012 1.00 101.51 ? 315 PHE C CD2 1 
ATOM 5883 C CE1 . PHE C 3 315 ? 108.478 156.721 148.733 1.00 90.06  ? 315 PHE C CE1 1 
ATOM 5884 C CE2 . PHE C 3 315 ? 108.058 158.406 150.363 1.00 99.02  ? 315 PHE C CE2 1 
ATOM 5885 C CZ  . PHE C 3 315 ? 107.685 157.733 149.222 1.00 91.94  ? 315 PHE C CZ  1 
ATOM 5886 N N   . ALA C 3 316 ? 113.499 159.197 151.247 1.00 105.99 ? 316 ALA C N   1 
ATOM 5887 C CA  . ALA C 3 316 ? 113.656 160.647 151.213 1.00 106.47 ? 316 ALA C CA  1 
ATOM 5888 C C   . ALA C 3 316 ? 114.346 161.105 149.935 1.00 107.03 ? 316 ALA C C   1 
ATOM 5889 O O   . ALA C 3 316 ? 113.968 162.127 149.352 1.00 111.60 ? 316 ALA C O   1 
ATOM 5890 C CB  . ALA C 3 316 ? 114.434 161.119 152.440 1.00 105.05 ? 316 ALA C CB  1 
ATOM 5891 N N   . ARG C 3 317 ? 115.353 160.363 149.479 1.00 103.75 ? 317 ARG C N   1 
ATOM 5892 C CA  . ARG C 3 317 ? 116.142 160.751 148.320 1.00 103.46 ? 317 ARG C CA  1 
ATOM 5893 C C   . ARG C 3 317 ? 115.762 159.994 147.053 1.00 102.45 ? 317 ARG C C   1 
ATOM 5894 O O   . ARG C 3 317 ? 116.443 160.139 146.034 1.00 103.28 ? 317 ARG C O   1 
ATOM 5895 C CB  . ARG C 3 317 ? 117.630 160.566 148.614 1.00 108.04 ? 317 ARG C CB  1 
ATOM 5896 C CG  . ARG C 3 317 ? 118.028 160.958 150.028 1.00 111.16 ? 317 ARG C CG  1 
ATOM 5897 C CD  . ARG C 3 317 ? 119.538 160.940 150.209 1.00 119.63 ? 317 ARG C CD  1 
ATOM 5898 N NE  . ARG C 3 317 ? 119.982 159.824 151.035 1.00 123.12 ? 317 ARG C NE  1 
ATOM 5899 C CZ  . ARG C 3 317 ? 120.329 158.634 150.563 1.00 123.44 ? 317 ARG C CZ  1 
ATOM 5900 N NH1 . ARG C 3 317 ? 120.296 158.369 149.267 1.00 120.40 ? 317 ARG C NH1 1 
ATOM 5901 N NH2 . ARG C 3 317 ? 120.720 157.688 151.412 1.00 122.32 ? 317 ARG C NH2 1 
ATOM 5902 N N   . TYR C 3 318 ? 114.701 159.193 147.088 1.00 103.37 ? 318 TYR C N   1 
ATOM 5903 C CA  . TYR C 3 318 ? 114.288 158.461 145.901 1.00 102.25 ? 318 TYR C CA  1 
ATOM 5904 C C   . TYR C 3 318 ? 113.567 159.377 144.917 1.00 103.01 ? 318 TYR C C   1 
ATOM 5905 O O   . TYR C 3 318 ? 112.814 160.276 145.297 1.00 105.27 ? 318 TYR C O   1 
ATOM 5906 C CB  . TYR C 3 318 ? 113.375 157.294 146.271 1.00 99.73  ? 318 TYR C CB  1 
ATOM 5907 C CG  . TYR C 3 318 ? 113.048 156.399 145.100 1.00 98.77  ? 318 TYR C CG  1 
ATOM 5908 C CD1 . TYR C 3 318 ? 114.040 155.666 144.462 1.00 98.27  ? 318 TYR C CD1 1 
ATOM 5909 C CD2 . TYR C 3 318 ? 111.751 156.310 144.613 1.00 97.71  ? 318 TYR C CD2 1 
ATOM 5910 C CE1 . TYR C 3 318 ? 113.745 154.851 143.385 1.00 95.56  ? 318 TYR C CE1 1 
ATOM 5911 C CE2 . TYR C 3 318 ? 111.447 155.501 143.536 1.00 96.00  ? 318 TYR C CE2 1 
ATOM 5912 C CZ  . TYR C 3 318 ? 112.447 154.775 142.927 1.00 95.25  ? 318 TYR C CZ  1 
ATOM 5913 O OH  . TYR C 3 318 ? 112.150 153.968 141.855 1.00 93.07  ? 318 TYR C OH  1 
ATOM 5914 N N   . THR C 3 319 ? 113.799 159.126 143.631 1.00 103.08 ? 319 THR C N   1 
ATOM 5915 C CA  . THR C 3 319 ? 113.179 159.888 142.559 1.00 103.72 ? 319 THR C CA  1 
ATOM 5916 C C   . THR C 3 319 ? 112.333 158.959 141.702 1.00 102.83 ? 319 THR C C   1 
ATOM 5917 O O   . THR C 3 319 ? 112.619 157.765 141.586 1.00 105.17 ? 319 THR C O   1 
ATOM 5918 C CB  . THR C 3 319 ? 114.221 160.593 141.683 1.00 104.94 ? 319 THR C CB  1 
ATOM 5919 O OG1 . THR C 3 319 ? 115.193 159.641 141.236 1.00 107.67 ? 319 THR C OG1 1 
ATOM 5920 C CG2 . THR C 3 319 ? 114.918 161.689 142.470 1.00 102.49 ? 319 THR C CG2 1 
ATOM 5921 N N   . THR C 3 320 ? 111.287 159.521 141.110 1.00 99.50  ? 320 THR C N   1 
ATOM 5922 C CA  . THR C 3 320 ? 110.361 158.727 140.311 1.00 97.85  ? 320 THR C CA  1 
ATOM 5923 C C   . THR C 3 320 ? 111.022 158.297 139.006 1.00 99.45  ? 320 THR C C   1 
ATOM 5924 O O   . THR C 3 320 ? 111.688 159.113 138.358 1.00 103.32 ? 320 THR C O   1 
ATOM 5925 C CB  . THR C 3 320 ? 109.099 159.526 140.017 1.00 95.85  ? 320 THR C CB  1 
ATOM 5926 O OG1 . THR C 3 320 ? 108.799 160.367 141.137 1.00 96.48  ? 320 THR C OG1 1 
ATOM 5927 C CG2 . THR C 3 320 ? 107.929 158.596 139.764 1.00 91.53  ? 320 THR C CG2 1 
ATOM 5928 N N   . PRO C 3 321 ? 110.882 157.038 138.599 1.00 97.97  ? 321 PRO C N   1 
ATOM 5929 C CA  . PRO C 3 321 ? 111.409 156.622 137.297 1.00 103.35 ? 321 PRO C CA  1 
ATOM 5930 C C   . PRO C 3 321 ? 110.612 157.231 136.154 1.00 108.25 ? 321 PRO C C   1 
ATOM 5931 O O   . PRO C 3 321 ? 109.489 157.712 136.322 1.00 109.37 ? 321 PRO C O   1 
ATOM 5932 C CB  . PRO C 3 321 ? 111.265 155.096 137.321 1.00 101.08 ? 321 PRO C CB  1 
ATOM 5933 C CG  . PRO C 3 321 ? 111.130 154.743 138.762 1.00 101.42 ? 321 PRO C CG  1 
ATOM 5934 C CD  . PRO C 3 321 ? 110.408 155.892 139.388 1.00 98.49  ? 321 PRO C CD  1 
ATOM 5935 N N   . GLU C 3 322 ? 111.231 157.214 134.971 1.00 107.14 ? 322 GLU C N   1 
ATOM 5936 C CA  . GLU C 3 322 ? 110.603 157.806 133.795 1.00 103.10 ? 322 GLU C CA  1 
ATOM 5937 C C   . GLU C 3 322 ? 109.391 157.000 133.343 1.00 102.75 ? 322 GLU C C   1 
ATOM 5938 O O   . GLU C 3 322 ? 108.401 157.570 132.871 1.00 101.22 ? 322 GLU C O   1 
ATOM 5939 C CB  . GLU C 3 322 ? 111.621 157.920 132.660 1.00 104.27 ? 322 GLU C CB  1 
ATOM 5940 C CG  . GLU C 3 322 ? 112.678 158.998 132.862 1.00 110.60 ? 322 GLU C CG  1 
ATOM 5941 C CD  . GLU C 3 322 ? 113.829 158.538 133.736 1.00 113.71 ? 322 GLU C CD  1 
ATOM 5942 O OE1 . GLU C 3 322 ? 114.289 157.390 133.560 1.00 113.35 ? 322 GLU C OE1 1 
ATOM 5943 O OE2 . GLU C 3 322 ? 114.273 159.324 134.600 1.00 114.79 ? 322 GLU C OE2 1 
ATOM 5944 N N   . ASP C 3 323 ? 109.447 155.677 133.485 1.00 103.81 ? 323 ASP C N   1 
ATOM 5945 C CA  . ASP C 3 323 ? 108.369 154.797 133.035 1.00 101.56 ? 323 ASP C CA  1 
ATOM 5946 C C   . ASP C 3 323 ? 107.243 154.837 134.058 1.00 101.47 ? 323 ASP C C   1 
ATOM 5947 O O   . ASP C 3 323 ? 107.175 154.020 134.976 1.00 100.45 ? 323 ASP C O   1 
ATOM 5948 C CB  . ASP C 3 323 ? 108.886 153.379 132.833 1.00 103.48 ? 323 ASP C CB  1 
ATOM 5949 C CG  . ASP C 3 323 ? 110.051 153.318 131.867 1.00 108.96 ? 323 ASP C CG  1 
ATOM 5950 O OD1 . ASP C 3 323 ? 110.430 154.376 131.323 1.00 111.54 ? 323 ASP C OD1 1 
ATOM 5951 O OD2 . ASP C 3 323 ? 110.590 152.213 131.655 1.00 109.79 ? 323 ASP C OD2 1 
ATOM 5952 N N   . ALA C 3 324 ? 106.344 155.801 133.894 1.00 102.10 ? 324 ALA C N   1 
ATOM 5953 C CA  . ALA C 3 324 ? 105.206 155.978 134.784 1.00 101.43 ? 324 ALA C CA  1 
ATOM 5954 C C   . ALA C 3 324 ? 103.965 155.361 134.156 1.00 105.04 ? 324 ALA C C   1 
ATOM 5955 O O   . ALA C 3 324 ? 103.717 155.537 132.959 1.00 111.81 ? 324 ALA C O   1 
ATOM 5956 C CB  . ALA C 3 324 ? 104.968 157.459 135.078 1.00 99.85  ? 324 ALA C CB  1 
ATOM 5957 N N   . THR C 3 325 ? 103.195 154.636 134.961 1.00 105.92 ? 325 THR C N   1 
ATOM 5958 C CA  . THR C 3 325 ? 101.966 154.019 134.482 1.00 115.07 ? 325 THR C CA  1 
ATOM 5959 C C   . THR C 3 325 ? 100.786 154.925 134.802 1.00 119.80 ? 325 THR C C   1 
ATOM 5960 O O   . THR C 3 325 ? 100.500 155.153 135.985 1.00 121.28 ? 325 THR C O   1 
ATOM 5961 C CB  . THR C 3 325 ? 101.762 152.658 135.121 1.00 116.26 ? 325 THR C CB  1 
ATOM 5962 O OG1 . THR C 3 325 ? 102.940 151.864 134.938 1.00 113.05 ? 325 THR C OG1 1 
ATOM 5963 C CG2 . THR C 3 325 ? 100.575 151.947 134.487 1.00 118.16 ? 325 THR C CG2 1 
ATOM 5964 N N   . PRO C 3 326 ? 100.081 155.455 133.804 1.00 123.27 ? 326 PRO C N   1 
ATOM 5965 C CA  . PRO C 3 326 ? 98.989  156.394 134.082 1.00 128.56 ? 326 PRO C CA  1 
ATOM 5966 C C   . PRO C 3 326 ? 97.648  155.707 134.287 1.00 132.45 ? 326 PRO C C   1 
ATOM 5967 O O   . PRO C 3 326 ? 97.310  154.719 133.631 1.00 134.28 ? 326 PRO C O   1 
ATOM 5968 C CB  . PRO C 3 326 ? 98.967  157.274 132.825 1.00 127.24 ? 326 PRO C CB  1 
ATOM 5969 C CG  . PRO C 3 326 ? 99.563  156.423 131.736 1.00 125.77 ? 326 PRO C CG  1 
ATOM 5970 C CD  . PRO C 3 326 ? 100.306 155.271 132.360 1.00 122.71 ? 326 PRO C CD  1 
ATOM 5971 N N   . GLU C 3 327 ? 96.874  156.262 135.216 1.00 134.19 ? 327 GLU C N   1 
ATOM 5972 C CA  . GLU C 3 327 ? 95.545  155.787 135.577 1.00 139.08 ? 327 GLU C CA  1 
ATOM 5973 C C   . GLU C 3 327 ? 94.893  156.961 136.299 1.00 142.08 ? 327 GLU C C   1 
ATOM 5974 O O   . GLU C 3 327 ? 95.545  157.596 137.138 1.00 141.13 ? 327 GLU C O   1 
ATOM 5975 C CB  . GLU C 3 327 ? 95.655  154.514 136.431 1.00 141.38 ? 327 GLU C CB  1 
ATOM 5976 C CG  . GLU C 3 327 ? 94.477  153.519 136.393 1.00 145.42 ? 327 GLU C CG  1 
ATOM 5977 C CD  . GLU C 3 327 ? 93.291  153.855 137.287 1.00 147.88 ? 327 GLU C CD  1 
ATOM 5978 O OE1 . GLU C 3 327 ? 93.174  154.990 137.777 1.00 147.83 ? 327 GLU C OE1 1 
ATOM 5979 O OE2 . GLU C 3 327 ? 92.455  152.953 137.502 1.00 147.13 ? 327 GLU C OE2 1 
ATOM 5980 N N   . PRO C 3 328 ? 93.643  157.306 135.972 1.00 147.33 ? 328 PRO C N   1 
ATOM 5981 C CA  . PRO C 3 328 ? 93.057  158.561 136.470 1.00 149.47 ? 328 PRO C CA  1 
ATOM 5982 C C   . PRO C 3 328 ? 92.908  158.604 137.985 1.00 148.88 ? 328 PRO C C   1 
ATOM 5983 O O   . PRO C 3 328 ? 92.576  157.610 138.633 1.00 148.16 ? 328 PRO C O   1 
ATOM 5984 C CB  . PRO C 3 328 ? 91.687  158.612 135.779 1.00 151.47 ? 328 PRO C CB  1 
ATOM 5985 C CG  . PRO C 3 328 ? 91.428  157.212 135.309 1.00 149.54 ? 328 PRO C CG  1 
ATOM 5986 C CD  . PRO C 3 328 ? 92.770  156.642 134.990 1.00 148.69 ? 328 PRO C CD  1 
ATOM 5987 N N   . GLY C 3 329 ? 93.143  159.787 138.542 1.00 147.98 ? 329 GLY C N   1 
ATOM 5988 C CA  . GLY C 3 329 ? 93.142  159.963 139.984 1.00 145.09 ? 329 GLY C CA  1 
ATOM 5989 C C   . GLY C 3 329 ? 94.272  159.255 140.701 1.00 142.80 ? 329 GLY C C   1 
ATOM 5990 O O   . GLY C 3 329 ? 94.044  158.637 141.749 1.00 141.59 ? 329 GLY C O   1 
ATOM 5991 N N   . GLU C 3 330 ? 95.488  159.328 140.165 1.00 141.25 ? 330 GLU C N   1 
ATOM 5992 C CA  . GLU C 3 330 ? 96.650  158.699 140.777 1.00 136.36 ? 330 GLU C CA  1 
ATOM 5993 C C   . GLU C 3 330 ? 97.378  159.726 141.635 1.00 131.25 ? 330 GLU C C   1 
ATOM 5994 O O   . GLU C 3 330 ? 97.767  160.789 141.141 1.00 130.24 ? 330 GLU C O   1 
ATOM 5995 C CB  . GLU C 3 330 ? 97.599  158.131 139.720 1.00 137.06 ? 330 GLU C CB  1 
ATOM 5996 C CG  . GLU C 3 330 ? 97.759  156.616 139.774 1.00 137.12 ? 330 GLU C CG  1 
ATOM 5997 C CD  . GLU C 3 330 ? 98.493  156.058 138.567 1.00 136.17 ? 330 GLU C CD  1 
ATOM 5998 O OE1 . GLU C 3 330 ? 98.166  156.450 137.430 1.00 138.41 ? 330 GLU C OE1 1 
ATOM 5999 O OE2 . GLU C 3 330 ? 99.383  155.202 138.752 1.00 131.01 ? 330 GLU C OE2 1 
ATOM 6000 N N   . ASP C 3 331 ? 97.548  159.410 142.911 1.00 129.74 ? 331 ASP C N   1 
ATOM 6001 C CA  . ASP C 3 331 ? 98.397  160.219 143.777 1.00 125.89 ? 331 ASP C CA  1 
ATOM 6002 C C   . ASP C 3 331 ? 99.849  160.059 143.341 1.00 119.76 ? 331 ASP C C   1 
ATOM 6003 O O   . ASP C 3 331 ? 100.302 158.927 143.134 1.00 118.55 ? 331 ASP C O   1 
ATOM 6004 C CB  . ASP C 3 331 ? 98.224  159.789 145.233 1.00 123.26 ? 331 ASP C CB  1 
ATOM 6005 C CG  . ASP C 3 331 ? 98.820  160.777 146.219 1.00 122.61 ? 331 ASP C CG  1 
ATOM 6006 O OD1 . ASP C 3 331 ? 98.978  161.963 145.868 1.00 122.76 ? 331 ASP C OD1 1 
ATOM 6007 O OD2 . ASP C 3 331 ? 99.135  160.362 147.354 1.00 122.26 ? 331 ASP C OD2 1 
ATOM 6008 N N   . PRO C 3 332 ? 100.589 161.152 143.134 1.00 115.97 ? 332 PRO C N   1 
ATOM 6009 C CA  . PRO C 3 332 ? 102.024 161.013 142.834 1.00 113.03 ? 332 PRO C CA  1 
ATOM 6010 C C   . PRO C 3 332 ? 102.816 160.333 143.937 1.00 109.37 ? 332 PRO C C   1 
ATOM 6011 O O   . PRO C 3 332 ? 103.779 159.611 143.641 1.00 107.77 ? 332 PRO C O   1 
ATOM 6012 C CB  . PRO C 3 332 ? 102.481 162.465 142.618 1.00 111.16 ? 332 PRO C CB  1 
ATOM 6013 C CG  . PRO C 3 332 ? 101.361 163.323 143.127 1.00 111.62 ? 332 PRO C CG  1 
ATOM 6014 C CD  . PRO C 3 332 ? 100.122 162.527 142.909 1.00 114.18 ? 332 PRO C CD  1 
ATOM 6015 N N   . ARG C 3 333 ? 102.425 160.525 145.199 1.00 109.27 ? 333 ARG C N   1 
ATOM 6016 C CA  . ARG C 3 333 ? 103.167 159.927 146.303 1.00 109.54 ? 333 ARG C CA  1 
ATOM 6017 C C   . ARG C 3 333 ? 103.006 158.413 146.332 1.00 107.17 ? 333 ARG C C   1 
ATOM 6018 O O   . ARG C 3 333 ? 103.971 157.689 146.607 1.00 106.97 ? 333 ARG C O   1 
ATOM 6019 C CB  . ARG C 3 333 ? 102.719 160.542 147.627 1.00 111.23 ? 333 ARG C CB  1 
ATOM 6020 C CG  . ARG C 3 333 ? 103.682 161.581 148.170 1.00 110.54 ? 333 ARG C CG  1 
ATOM 6021 C CD  . ARG C 3 333 ? 102.937 162.688 148.912 1.00 111.31 ? 333 ARG C CD  1 
ATOM 6022 N NE  . ARG C 3 333 ? 102.322 163.671 148.023 1.00 114.69 ? 333 ARG C NE  1 
ATOM 6023 C CZ  . ARG C 3 333 ? 102.974 164.534 147.252 1.00 113.56 ? 333 ARG C CZ  1 
ATOM 6024 N NH1 . ARG C 3 333 ? 104.293 164.644 147.286 1.00 113.11 ? 333 ARG C NH1 1 
ATOM 6025 N NH2 . ARG C 3 333 ? 102.281 165.328 146.440 1.00 112.58 ? 333 ARG C NH2 1 
ATOM 6026 N N   . VAL C 3 334 ? 101.800 157.911 146.045 1.00 106.00 ? 334 VAL C N   1 
ATOM 6027 C CA  . VAL C 3 334 ? 101.608 156.464 146.072 1.00 104.03 ? 334 VAL C CA  1 
ATOM 6028 C C   . VAL C 3 334 ? 102.310 155.809 144.890 1.00 96.73  ? 334 VAL C C   1 
ATOM 6029 O O   . VAL C 3 334 ? 102.819 154.691 145.013 1.00 95.65  ? 334 VAL C O   1 
ATOM 6030 C CB  . VAL C 3 334 ? 100.107 156.096 146.157 1.00 108.41 ? 334 VAL C CB  1 
ATOM 6031 C CG1 . VAL C 3 334 ? 99.368  156.310 144.844 1.00 106.20 ? 334 VAL C CG1 1 
ATOM 6032 C CG2 . VAL C 3 334 ? 99.947  154.658 146.628 1.00 110.22 ? 334 VAL C CG2 1 
ATOM 6033 N N   . THR C 3 335 ? 102.407 156.506 143.753 1.00 94.99  ? 335 THR C N   1 
ATOM 6034 C CA  . THR C 3 335 ? 103.168 155.967 142.633 1.00 95.33  ? 335 THR C CA  1 
ATOM 6035 C C   . THR C 3 335 ? 104.654 155.953 142.946 1.00 95.19  ? 335 THR C C   1 
ATOM 6036 O O   . THR C 3 335 ? 105.357 154.995 142.604 1.00 96.58  ? 335 THR C O   1 
ATOM 6037 C CB  . THR C 3 335 ? 102.910 156.776 141.367 1.00 101.38 ? 335 THR C CB  1 
ATOM 6038 O OG1 . THR C 3 335 ? 103.054 158.169 141.656 1.00 106.60 ? 335 THR C OG1 1 
ATOM 6039 C CG2 . THR C 3 335 ? 101.507 156.523 140.859 1.00 108.30 ? 335 THR C CG2 1 
ATOM 6040 N N   . ARG C 3 336 ? 105.142 157.006 143.609 1.00 97.41  ? 336 ARG C N   1 
ATOM 6041 C CA  . ARG C 3 336 ? 106.541 157.059 144.022 1.00 100.79 ? 336 ARG C CA  1 
ATOM 6042 C C   . ARG C 3 336 ? 106.873 155.919 144.981 1.00 96.54  ? 336 ARG C C   1 
ATOM 6043 O O   . ARG C 3 336 ? 107.887 155.228 144.818 1.00 92.12  ? 336 ARG C O   1 
ATOM 6044 C CB  . ARG C 3 336 ? 106.828 158.417 144.665 1.00 102.41 ? 336 ARG C CB  1 
ATOM 6045 C CG  . ARG C 3 336 ? 108.273 158.669 145.029 1.00 98.82  ? 336 ARG C CG  1 
ATOM 6046 C CD  . ARG C 3 336 ? 108.415 160.035 145.671 1.00 93.26  ? 336 ARG C CD  1 
ATOM 6047 N NE  . ARG C 3 336 ? 109.796 160.350 146.009 1.00 96.91  ? 336 ARG C NE  1 
ATOM 6048 C CZ  . ARG C 3 336 ? 110.206 161.532 146.445 1.00 106.38 ? 336 ARG C CZ  1 
ATOM 6049 N NH1 . ARG C 3 336 ? 109.365 162.540 146.603 1.00 113.02 ? 336 ARG C NH1 1 
ATOM 6050 N NH2 . ARG C 3 336 ? 111.493 161.708 146.730 1.00 107.64 ? 336 ARG C NH2 1 
ATOM 6051 N N   . ALA C 3 337 ? 105.995 155.681 145.960 1.00 95.69  ? 337 ALA C N   1 
ATOM 6052 C CA  . ALA C 3 337 ? 106.214 154.603 146.921 1.00 89.67  ? 337 ALA C CA  1 
ATOM 6053 C C   . ALA C 3 337 ? 106.125 153.234 146.261 1.00 83.03  ? 337 ALA C C   1 
ATOM 6054 O O   . ALA C 3 337 ? 106.926 152.342 146.557 1.00 84.93  ? 337 ALA C O   1 
ATOM 6055 C CB  . ALA C 3 337 ? 105.206 154.712 148.065 1.00 91.86  ? 337 ALA C CB  1 
ATOM 6056 N N   . LYS C 3 338 ? 105.160 153.054 145.361 1.00 81.93  ? 338 LYS C N   1 
ATOM 6057 C CA  . LYS C 3 338 ? 104.960 151.777 144.691 1.00 82.74  ? 338 LYS C CA  1 
ATOM 6058 C C   . LYS C 3 338 ? 106.125 151.444 143.762 1.00 78.31  ? 338 LYS C C   1 
ATOM 6059 O O   . LYS C 3 338 ? 106.583 150.292 143.724 1.00 80.50  ? 338 LYS C O   1 
ATOM 6060 C CB  . LYS C 3 338 ? 103.586 151.841 144.005 1.00 86.08  ? 338 LYS C CB  1 
ATOM 6061 C CG  . LYS C 3 338 ? 103.516 152.271 142.551 1.00 90.10  ? 338 LYS C CG  1 
ATOM 6062 C CD  . LYS C 3 338 ? 102.059 152.354 142.087 1.00 93.16  ? 338 LYS C CD  1 
ATOM 6063 C CE  . LYS C 3 338 ? 101.373 151.021 141.984 1.00 89.45  ? 338 LYS C CE  1 
ATOM 6064 N NZ  . LYS C 3 338 ? 101.985 150.251 140.895 1.00 88.20  ? 338 LYS C NZ  1 
ATOM 6065 N N   . TYR C 3 339 ? 106.697 152.444 143.095 1.00 77.58  ? 339 TYR C N   1 
ATOM 6066 C CA  . TYR C 3 339 ? 107.849 152.158 142.258 1.00 82.46  ? 339 TYR C CA  1 
ATOM 6067 C C   . TYR C 3 339 ? 109.130 152.028 143.076 1.00 86.68  ? 339 TYR C C   1 
ATOM 6068 O O   . TYR C 3 339 ? 110.049 151.314 142.658 1.00 87.09  ? 339 TYR C O   1 
ATOM 6069 C CB  . TYR C 3 339 ? 107.980 153.222 141.171 1.00 88.77  ? 339 TYR C CB  1 
ATOM 6070 C CG  . TYR C 3 339 ? 107.070 152.947 139.993 1.00 88.19  ? 339 TYR C CG  1 
ATOM 6071 C CD1 . TYR C 3 339 ? 107.399 151.997 139.043 1.00 84.89  ? 339 TYR C CD1 1 
ATOM 6072 C CD2 . TYR C 3 339 ? 105.875 153.631 139.845 1.00 91.06  ? 339 TYR C CD2 1 
ATOM 6073 C CE1 . TYR C 3 339 ? 106.566 151.742 137.978 1.00 88.63  ? 339 TYR C CE1 1 
ATOM 6074 C CE2 . TYR C 3 339 ? 105.038 153.383 138.782 1.00 93.81  ? 339 TYR C CE2 1 
ATOM 6075 C CZ  . TYR C 3 339 ? 105.391 152.436 137.850 1.00 96.33  ? 339 TYR C CZ  1 
ATOM 6076 O OH  . TYR C 3 339 ? 104.570 152.173 136.781 1.00 106.20 ? 339 TYR C OH  1 
ATOM 6077 N N   . PHE C 3 340 ? 109.208 152.672 144.248 1.00 87.42  ? 340 PHE C N   1 
ATOM 6078 C CA  . PHE C 3 340 ? 110.324 152.401 145.156 1.00 83.61  ? 340 PHE C CA  1 
ATOM 6079 C C   . PHE C 3 340 ? 110.271 150.976 145.685 1.00 78.13  ? 340 PHE C C   1 
ATOM 6080 O O   . PHE C 3 340 ? 111.313 150.325 145.846 1.00 78.43  ? 340 PHE C O   1 
ATOM 6081 C CB  . PHE C 3 340 ? 110.318 153.388 146.319 1.00 86.63  ? 340 PHE C CB  1 
ATOM 6082 C CG  . PHE C 3 340 ? 111.397 153.130 147.329 1.00 87.46  ? 340 PHE C CG  1 
ATOM 6083 C CD1 . PHE C 3 340 ? 112.723 153.055 146.941 1.00 90.69  ? 340 PHE C CD1 1 
ATOM 6084 C CD2 . PHE C 3 340 ? 111.083 152.955 148.664 1.00 87.17  ? 340 PHE C CD2 1 
ATOM 6085 C CE1 . PHE C 3 340 ? 113.720 152.814 147.870 1.00 93.80  ? 340 PHE C CE1 1 
ATOM 6086 C CE2 . PHE C 3 340 ? 112.071 152.715 149.597 1.00 88.64  ? 340 PHE C CE2 1 
ATOM 6087 C CZ  . PHE C 3 340 ? 113.391 152.643 149.201 1.00 92.17  ? 340 PHE C CZ  1 
ATOM 6088 N N   . ILE C 3 341 ? 109.064 150.488 145.975 1.00 77.18  ? 341 ILE C N   1 
ATOM 6089 C CA  . ILE C 3 341 ? 108.881 149.102 146.391 1.00 70.23  ? 341 ILE C CA  1 
ATOM 6090 C C   . ILE C 3 341 ? 109.305 148.161 145.273 1.00 65.69  ? 341 ILE C C   1 
ATOM 6091 O O   . ILE C 3 341 ? 109.954 147.138 145.523 1.00 69.79  ? 341 ILE C O   1 
ATOM 6092 C CB  . ILE C 3 341 ? 107.422 148.872 146.835 1.00 73.15  ? 341 ILE C CB  1 
ATOM 6093 C CG1 . ILE C 3 341 ? 107.230 149.332 148.276 1.00 80.84  ? 341 ILE C CG1 1 
ATOM 6094 C CG2 . ILE C 3 341 ? 107.014 147.421 146.722 1.00 76.01  ? 341 ILE C CG2 1 
ATOM 6095 C CD1 . ILE C 3 341 ? 105.884 149.946 148.549 1.00 86.05  ? 341 ILE C CD1 1 
ATOM 6096 N N   . ARG C 3 342 ? 108.990 148.516 144.023 1.00 65.58  ? 342 ARG C N   1 
ATOM 6097 C CA  . ARG C 3 342 ? 109.501 147.755 142.883 1.00 63.81  ? 342 ARG C CA  1 
ATOM 6098 C C   . ARG C 3 342 ? 111.029 147.749 142.849 1.00 67.77  ? 342 ARG C C   1 
ATOM 6099 O O   . ARG C 3 342 ? 111.656 146.693 142.701 1.00 72.30  ? 342 ARG C O   1 
ATOM 6100 C CB  . ARG C 3 342 ? 108.970 148.335 141.573 1.00 69.18  ? 342 ARG C CB  1 
ATOM 6101 C CG  . ARG C 3 342 ? 109.400 147.509 140.382 1.00 63.81  ? 342 ARG C CG  1 
ATOM 6102 C CD  . ARG C 3 342 ? 108.342 147.357 139.294 1.00 63.03  ? 342 ARG C CD  1 
ATOM 6103 N NE  . ARG C 3 342 ? 108.238 148.487 138.374 1.00 67.60  ? 342 ARG C NE  1 
ATOM 6104 C CZ  . ARG C 3 342 ? 109.206 148.923 137.574 1.00 71.76  ? 342 ARG C CZ  1 
ATOM 6105 N NH1 . ARG C 3 342 ? 110.343 148.261 137.424 1.00 71.93  ? 342 ARG C NH1 1 
ATOM 6106 N NH2 . ARG C 3 342 ? 109.008 150.024 136.858 1.00 76.32  ? 342 ARG C NH2 1 
ATOM 6107 N N   . ASP C 3 343 ? 111.641 148.923 143.011 1.00 72.28  ? 343 ASP C N   1 
ATOM 6108 C CA  . ASP C 3 343 ? 113.089 149.065 142.873 1.00 77.02  ? 343 ASP C CA  1 
ATOM 6109 C C   . ASP C 3 343 ? 113.845 148.316 143.962 1.00 74.84  ? 343 ASP C C   1 
ATOM 6110 O O   . ASP C 3 343 ? 114.946 147.807 143.711 1.00 75.01  ? 343 ASP C O   1 
ATOM 6111 C CB  . ASP C 3 343 ? 113.457 150.550 142.883 1.00 86.07  ? 343 ASP C CB  1 
ATOM 6112 C CG  . ASP C 3 343 ? 114.948 150.785 143.011 1.00 89.20  ? 343 ASP C CG  1 
ATOM 6113 O OD1 . ASP C 3 343 ? 115.700 150.363 142.107 1.00 90.97  ? 343 ASP C OD1 1 
ATOM 6114 O OD2 . ASP C 3 343 ? 115.361 151.395 144.015 1.00 88.15  ? 343 ASP C OD2 1 
ATOM 6115 N N   . GLU C 3 344 ? 113.266 148.228 145.162 1.00 73.19  ? 344 GLU C N   1 
ATOM 6116 C CA  . GLU C 3 344 ? 113.882 147.447 146.232 1.00 69.61  ? 344 GLU C CA  1 
ATOM 6117 C C   . GLU C 3 344 ? 113.985 145.974 145.857 1.00 65.49  ? 344 GLU C C   1 
ATOM 6118 O O   . GLU C 3 344 ? 114.959 145.302 146.215 1.00 68.27  ? 344 GLU C O   1 
ATOM 6119 C CB  . GLU C 3 344 ? 113.091 147.612 147.528 1.00 70.36  ? 344 GLU C CB  1 
ATOM 6120 C CG  . GLU C 3 344 ? 113.441 148.857 148.324 1.00 78.28  ? 344 GLU C CG  1 
ATOM 6121 C CD  . GLU C 3 344 ? 114.933 149.068 148.456 1.00 88.27  ? 344 GLU C CD  1 
ATOM 6122 O OE1 . GLU C 3 344 ? 115.567 148.335 149.243 1.00 90.29  ? 344 GLU C OE1 1 
ATOM 6123 O OE2 . GLU C 3 344 ? 115.475 149.966 147.779 1.00 92.32  ? 344 GLU C OE2 1 
ATOM 6124 N N   . PHE C 3 345 ? 112.991 145.453 145.137 1.00 62.80  ? 345 PHE C N   1 
ATOM 6125 C CA  . PHE C 3 345 ? 113.052 144.064 144.697 1.00 60.43  ? 345 PHE C CA  1 
ATOM 6126 C C   . PHE C 3 345 ? 114.016 143.894 143.526 1.00 61.88  ? 345 PHE C C   1 
ATOM 6127 O O   . PHE C 3 345 ? 114.784 142.923 143.475 1.00 65.37  ? 345 PHE C O   1 
ATOM 6128 C CB  . PHE C 3 345 ? 111.651 143.585 144.323 1.00 58.41  ? 345 PHE C CB  1 
ATOM 6129 C CG  . PHE C 3 345 ? 110.800 143.198 145.505 1.00 58.31  ? 345 PHE C CG  1 
ATOM 6130 C CD1 . PHE C 3 345 ? 110.927 141.963 146.101 1.00 63.67  ? 345 PHE C CD1 1 
ATOM 6131 C CD2 . PHE C 3 345 ? 109.858 144.072 146.005 1.00 61.72  ? 345 PHE C CD2 1 
ATOM 6132 C CE1 . PHE C 3 345 ? 110.145 141.612 147.178 1.00 65.67  ? 345 PHE C CE1 1 
ATOM 6133 C CE2 . PHE C 3 345 ? 109.071 143.728 147.083 1.00 66.08  ? 345 PHE C CE2 1 
ATOM 6134 C CZ  . PHE C 3 345 ? 109.214 142.496 147.666 1.00 67.51  ? 345 PHE C CZ  1 
ATOM 6135 N N   . LEU C 3 346 ? 114.006 144.836 142.577 1.00 59.81  ? 346 LEU C N   1 
ATOM 6136 C CA  . LEU C 3 346 ? 114.935 144.719 141.450 1.00 63.45  ? 346 LEU C CA  1 
ATOM 6137 C C   . LEU C 3 346 ? 116.393 144.939 141.818 1.00 67.29  ? 346 LEU C C   1 
ATOM 6138 O O   . LEU C 3 346 ? 117.259 144.500 141.057 1.00 69.62  ? 346 LEU C O   1 
ATOM 6139 C CB  . LEU C 3 346 ? 114.587 145.646 140.285 1.00 66.32  ? 346 LEU C CB  1 
ATOM 6140 C CG  . LEU C 3 346 ? 113.497 145.203 139.310 1.00 68.15  ? 346 LEU C CG  1 
ATOM 6141 C CD1 . LEU C 3 346 ? 113.728 143.769 138.902 1.00 68.26  ? 346 LEU C CD1 1 
ATOM 6142 C CD2 . LEU C 3 346 ? 112.168 145.313 139.887 1.00 66.50  ? 346 LEU C CD2 1 
ATOM 6143 N N   . ARG C 3 347 ? 116.698 145.601 142.934 1.00 67.18  ? 347 ARG C N   1 
ATOM 6144 C CA  . ARG C 3 347 ? 118.094 145.663 143.361 1.00 63.87  ? 347 ARG C CA  1 
ATOM 6145 C C   . ARG C 3 347 ? 118.636 144.268 143.657 1.00 63.11  ? 347 ARG C C   1 
ATOM 6146 O O   . ARG C 3 347 ? 119.710 143.890 143.174 1.00 65.19  ? 347 ARG C O   1 
ATOM 6147 C CB  . ARG C 3 347 ? 118.244 146.572 144.578 1.00 68.82  ? 347 ARG C CB  1 
ATOM 6148 C CG  . ARG C 3 347 ? 119.650 147.142 144.724 1.00 76.23  ? 347 ARG C CG  1 
ATOM 6149 C CD  . ARG C 3 347 ? 119.831 148.049 145.962 1.00 79.21  ? 347 ARG C CD  1 
ATOM 6150 N NE  . ARG C 3 347 ? 118.754 148.972 146.332 1.00 82.90  ? 347 ARG C NE  1 
ATOM 6151 C CZ  . ARG C 3 347 ? 118.125 149.841 145.543 1.00 82.76  ? 347 ARG C CZ  1 
ATOM 6152 N NH1 . ARG C 3 347 ? 118.517 150.077 144.300 1.00 79.20  ? 347 ARG C NH1 1 
ATOM 6153 N NH2 . ARG C 3 347 ? 117.103 150.534 146.035 1.00 86.54  ? 347 ARG C NH2 1 
ATOM 6154 N N   . ILE C 3 348 ? 117.862 143.463 144.387 1.00 60.43  ? 348 ILE C N   1 
ATOM 6155 C CA  . ILE C 3 348 ? 118.222 142.066 144.608 1.00 57.11  ? 348 ILE C CA  1 
ATOM 6156 C C   . ILE C 3 348 ? 118.188 141.282 143.304 1.00 60.69  ? 348 ILE C C   1 
ATOM 6157 O O   . ILE C 3 348 ? 119.009 140.383 143.089 1.00 60.18  ? 348 ILE C O   1 
ATOM 6158 C CB  . ILE C 3 348 ? 117.289 141.434 145.652 1.00 59.32  ? 348 ILE C CB  1 
ATOM 6159 C CG1 . ILE C 3 348 ? 117.015 142.410 146.795 1.00 61.05  ? 348 ILE C CG1 1 
ATOM 6160 C CG2 . ILE C 3 348 ? 117.863 140.128 146.145 1.00 65.65  ? 348 ILE C CG2 1 
ATOM 6161 C CD1 . ILE C 3 348 ? 115.660 142.224 147.435 1.00 63.71  ? 348 ILE C CD1 1 
ATOM 6162 N N   . SER C 3 349 ? 117.230 141.593 142.426 1.00 62.44  ? 349 SER C N   1 
ATOM 6163 C CA  . SER C 3 349 ? 117.079 140.821 141.194 1.00 62.43  ? 349 SER C CA  1 
ATOM 6164 C C   . SER C 3 349 ? 118.271 140.996 140.257 1.00 62.39  ? 349 SER C C   1 
ATOM 6165 O O   . SER C 3 349 ? 118.757 140.021 139.675 1.00 68.01  ? 349 SER C O   1 
ATOM 6166 C CB  . SER C 3 349 ? 115.784 141.207 140.489 1.00 64.24  ? 349 SER C CB  1 
ATOM 6167 O OG  . SER C 3 349 ? 115.844 140.891 139.110 1.00 68.54  ? 349 SER C OG  1 
ATOM 6168 N N   . THR C 3 350 ? 118.764 142.220 140.099 1.00 58.12  ? 350 THR C N   1 
ATOM 6169 C CA  . THR C 3 350 ? 119.925 142.457 139.253 1.00 57.87  ? 350 THR C CA  1 
ATOM 6170 C C   . THR C 3 350 ? 121.241 142.478 140.017 1.00 62.31  ? 350 THR C C   1 
ATOM 6171 O O   . THR C 3 350 ? 122.275 142.789 139.420 1.00 65.88  ? 350 THR C O   1 
ATOM 6172 C CB  . THR C 3 350 ? 119.774 143.764 138.466 1.00 63.15  ? 350 THR C CB  1 
ATOM 6173 O OG1 . THR C 3 350 ? 120.287 144.857 139.238 1.00 67.14  ? 350 THR C OG1 1 
ATOM 6174 C CG2 . THR C 3 350 ? 118.327 144.012 138.069 1.00 64.62  ? 350 THR C CG2 1 
ATOM 6175 N N   . ALA C 3 351 ? 121.234 142.179 141.319 1.00 66.74  ? 351 ALA C N   1 
ATOM 6176 C CA  . ALA C 3 351 ? 122.500 141.972 142.017 1.00 67.40  ? 351 ALA C CA  1 
ATOM 6177 C C   . ALA C 3 351 ? 123.236 140.739 141.501 1.00 66.04  ? 351 ALA C C   1 
ATOM 6178 O O   . ALA C 3 351 ? 124.456 140.777 141.308 1.00 65.74  ? 351 ALA C O   1 
ATOM 6179 C CB  . ALA C 3 351 ? 122.256 141.858 143.521 1.00 67.21  ? 351 ALA C CB  1 
ATOM 6180 N N   . SER C 3 352 ? 122.519 139.638 141.270 1.00 67.10  ? 352 SER C N   1 
ATOM 6181 C CA  . SER C 3 352 ? 123.153 138.386 140.884 1.00 70.14  ? 352 SER C CA  1 
ATOM 6182 C C   . SER C 3 352 ? 122.488 137.670 139.718 1.00 74.37  ? 352 SER C C   1 
ATOM 6183 O O   . SER C 3 352 ? 123.065 136.701 139.214 1.00 74.93  ? 352 SER C O   1 
ATOM 6184 C CB  . SER C 3 352 ? 123.206 137.422 142.078 1.00 72.80  ? 352 SER C CB  1 
ATOM 6185 O OG  . SER C 3 352 ? 122.072 137.585 142.913 1.00 71.72  ? 352 SER C OG  1 
ATOM 6186 N N   . GLY C 3 353 ? 121.304 138.094 139.284 1.00 76.65  ? 353 GLY C N   1 
ATOM 6187 C CA  . GLY C 3 353 ? 120.647 137.449 138.162 1.00 79.90  ? 353 GLY C CA  1 
ATOM 6188 C C   . GLY C 3 353 ? 121.324 137.818 136.858 1.00 89.12  ? 353 GLY C C   1 
ATOM 6189 O O   . GLY C 3 353 ? 121.302 138.991 136.449 1.00 92.52  ? 353 GLY C O   1 
ATOM 6190 N N   . ASP C 3 354 ? 121.928 136.834 136.187 1.00 87.62  ? 354 ASP C N   1 
ATOM 6191 C CA  . ASP C 3 354 ? 122.703 137.083 134.969 1.00 85.39  ? 354 ASP C CA  1 
ATOM 6192 C C   . ASP C 3 354 ? 122.366 136.000 133.946 1.00 80.08  ? 354 ASP C C   1 
ATOM 6193 O O   . ASP C 3 354 ? 123.022 134.958 133.889 1.00 78.85  ? 354 ASP C O   1 
ATOM 6194 C CB  . ASP C 3 354 ? 124.192 137.119 135.280 1.00 88.63  ? 354 ASP C CB  1 
ATOM 6195 C CG  . ASP C 3 354 ? 124.583 136.126 136.356 1.00 92.61  ? 354 ASP C CG  1 
ATOM 6196 O OD1 . ASP C 3 354 ? 123.725 135.305 136.744 1.00 91.22  ? 354 ASP C OD1 1 
ATOM 6197 O OD2 . ASP C 3 354 ? 125.744 136.167 136.813 1.00 95.99  ? 354 ASP C OD2 1 
ATOM 6198 N N   . GLY C 3 355 ? 121.347 136.260 133.135 1.00 79.13  ? 355 GLY C N   1 
ATOM 6199 C CA  . GLY C 3 355 ? 121.019 135.390 132.023 1.00 79.57  ? 355 GLY C CA  1 
ATOM 6200 C C   . GLY C 3 355 ? 120.166 134.184 132.357 1.00 76.73  ? 355 GLY C C   1 
ATOM 6201 O O   . GLY C 3 355 ? 119.241 133.853 131.609 1.00 76.20  ? 355 GLY C O   1 
ATOM 6202 N N   . ARG C 3 356 ? 120.474 133.514 133.471 1.00 74.52  ? 356 ARG C N   1 
ATOM 6203 C CA  . ARG C 3 356 ? 119.818 132.249 133.790 1.00 69.34  ? 356 ARG C CA  1 
ATOM 6204 C C   . ARG C 3 356 ? 118.353 132.451 134.149 1.00 64.67  ? 356 ARG C C   1 
ATOM 6205 O O   . ARG C 3 356 ? 117.495 131.659 133.744 1.00 66.14  ? 356 ARG C O   1 
ATOM 6206 C CB  . ARG C 3 356 ? 120.557 131.553 134.929 1.00 69.21  ? 356 ARG C CB  1 
ATOM 6207 C CG  . ARG C 3 356 ? 121.824 130.843 134.500 1.00 74.19  ? 356 ARG C CG  1 
ATOM 6208 C CD  . ARG C 3 356 ? 121.756 129.362 134.809 1.00 79.11  ? 356 ARG C CD  1 
ATOM 6209 N NE  . ARG C 3 356 ? 122.925 128.643 134.317 1.00 86.75  ? 356 ARG C NE  1 
ATOM 6210 C CZ  . ARG C 3 356 ? 122.910 127.384 133.901 1.00 90.17  ? 356 ARG C CZ  1 
ATOM 6211 N NH1 . ARG C 3 356 ? 121.798 126.668 133.904 1.00 87.54  ? 356 ARG C NH1 1 
ATOM 6212 N NH2 . ARG C 3 356 ? 124.040 126.829 133.472 1.00 94.51  ? 356 ARG C NH2 1 
ATOM 6213 N N   . HIS C 3 357 ? 118.045 133.503 134.900 1.00 62.94  ? 357 HIS C N   1 
ATOM 6214 C CA  . HIS C 3 357 ? 116.687 133.735 135.361 1.00 59.97  ? 357 HIS C CA  1 
ATOM 6215 C C   . HIS C 3 357 ? 116.490 135.219 135.615 1.00 61.77  ? 357 HIS C C   1 
ATOM 6216 O O   . HIS C 3 357 ? 117.450 135.969 135.805 1.00 70.36  ? 357 HIS C O   1 
ATOM 6217 C CB  . HIS C 3 357 ? 116.378 132.920 136.619 1.00 58.13  ? 357 HIS C CB  1 
ATOM 6218 C CG  . HIS C 3 357 ? 117.099 133.384 137.847 1.00 57.77  ? 357 HIS C CG  1 
ATOM 6219 N ND1 . HIS C 3 357 ? 118.384 133.877 137.823 1.00 58.05  ? 357 HIS C ND1 1 
ATOM 6220 C CD2 . HIS C 3 357 ? 116.715 133.404 139.144 1.00 59.99  ? 357 HIS C CD2 1 
ATOM 6221 C CE1 . HIS C 3 357 ? 118.756 134.193 139.049 1.00 59.60  ? 357 HIS C CE1 1 
ATOM 6222 N NE2 . HIS C 3 357 ? 117.760 133.920 139.869 1.00 59.47  ? 357 HIS C NE2 1 
ATOM 6223 N N   . TYR C 3 358 ? 115.228 135.637 135.617 1.00 53.41  ? 358 TYR C N   1 
ATOM 6224 C CA  . TYR C 3 358 ? 114.886 137.041 135.766 1.00 54.70  ? 358 TYR C CA  1 
ATOM 6225 C C   . TYR C 3 358 ? 113.620 137.168 136.598 1.00 55.05  ? 358 TYR C C   1 
ATOM 6226 O O   . TYR C 3 358 ? 112.923 136.187 136.865 1.00 59.66  ? 358 TYR C O   1 
ATOM 6227 C CB  . TYR C 3 358 ? 114.715 137.719 134.405 1.00 61.57  ? 358 TYR C CB  1 
ATOM 6228 C CG  . TYR C 3 358 ? 116.014 137.891 133.662 1.00 67.02  ? 358 TYR C CG  1 
ATOM 6229 C CD1 . TYR C 3 358 ? 116.911 138.886 134.021 1.00 69.45  ? 358 TYR C CD1 1 
ATOM 6230 C CD2 . TYR C 3 358 ? 116.352 137.050 132.613 1.00 68.42  ? 358 TYR C CD2 1 
ATOM 6231 C CE1 . TYR C 3 358 ? 118.103 139.044 133.350 1.00 75.52  ? 358 TYR C CE1 1 
ATOM 6232 C CE2 . TYR C 3 358 ? 117.541 137.200 131.937 1.00 70.89  ? 358 TYR C CE2 1 
ATOM 6233 C CZ  . TYR C 3 358 ? 118.414 138.197 132.312 1.00 76.94  ? 358 TYR C CZ  1 
ATOM 6234 O OH  . TYR C 3 358 ? 119.603 138.356 131.638 1.00 82.67  ? 358 TYR C OH  1 
ATOM 6235 N N   . CYS C 3 359 ? 113.333 138.395 137.018 1.00 56.28  ? 359 CYS C N   1 
ATOM 6236 C CA  . CYS C 3 359 ? 112.134 138.721 137.773 1.00 54.53  ? 359 CYS C CA  1 
ATOM 6237 C C   . CYS C 3 359 ? 111.162 139.499 136.897 1.00 56.24  ? 359 CYS C C   1 
ATOM 6238 O O   . CYS C 3 359 ? 111.566 140.210 135.973 1.00 61.80  ? 359 CYS C O   1 
ATOM 6239 C CB  . CYS C 3 359 ? 112.470 139.541 139.017 1.00 60.34  ? 359 CYS C CB  1 
ATOM 6240 S SG  . CYS C 3 359 ? 111.023 140.093 139.940 1.00 77.03  ? 359 CYS C SG  1 
ATOM 6241 N N   . TYR C 3 360 ? 109.873 139.363 137.196 1.00 52.47  ? 360 TYR C N   1 
ATOM 6242 C CA  . TYR C 3 360 ? 108.810 140.002 136.422 1.00 55.29  ? 360 TYR C CA  1 
ATOM 6243 C C   . TYR C 3 360 ? 107.895 140.754 137.376 1.00 59.32  ? 360 TYR C C   1 
ATOM 6244 O O   . TYR C 3 360 ? 106.850 140.236 137.795 1.00 64.90  ? 360 TYR C O   1 
ATOM 6245 C CB  . TYR C 3 360 ? 108.043 138.975 135.599 1.00 57.72  ? 360 TYR C CB  1 
ATOM 6246 C CG  . TYR C 3 360 ? 108.871 138.361 134.501 1.00 58.97  ? 360 TYR C CG  1 
ATOM 6247 C CD1 . TYR C 3 360 ? 108.887 138.907 133.228 1.00 62.46  ? 360 TYR C CD1 1 
ATOM 6248 C CD2 . TYR C 3 360 ? 109.660 137.253 134.746 1.00 58.03  ? 360 TYR C CD2 1 
ATOM 6249 C CE1 . TYR C 3 360 ? 109.652 138.348 132.228 1.00 62.64  ? 360 TYR C CE1 1 
ATOM 6250 C CE2 . TYR C 3 360 ? 110.425 136.699 133.762 1.00 57.88  ? 360 TYR C CE2 1 
ATOM 6251 C CZ  . TYR C 3 360 ? 110.419 137.241 132.508 1.00 62.49  ? 360 TYR C CZ  1 
ATOM 6252 O OH  . TYR C 3 360 ? 111.190 136.668 131.529 1.00 68.20  ? 360 TYR C OH  1 
ATOM 6253 N N   . PRO C 3 361 ? 108.253 141.978 137.741 1.00 56.50  ? 361 PRO C N   1 
ATOM 6254 C CA  . PRO C 3 361 ? 107.505 142.697 138.779 1.00 61.13  ? 361 PRO C CA  1 
ATOM 6255 C C   . PRO C 3 361 ? 106.256 143.393 138.262 1.00 63.91  ? 361 PRO C C   1 
ATOM 6256 O O   . PRO C 3 361 ? 106.331 144.428 137.592 1.00 66.25  ? 361 PRO C O   1 
ATOM 6257 C CB  . PRO C 3 361 ? 108.535 143.705 139.293 1.00 67.01  ? 361 PRO C CB  1 
ATOM 6258 C CG  . PRO C 3 361 ? 109.416 143.957 138.106 1.00 65.41  ? 361 PRO C CG  1 
ATOM 6259 C CD  . PRO C 3 361 ? 109.398 142.750 137.234 1.00 61.84  ? 361 PRO C CD  1 
ATOM 6260 N N   . HIS C 3 362 ? 105.090 142.830 138.558 1.00 60.44  ? 362 HIS C N   1 
ATOM 6261 C CA  . HIS C 3 362 ? 103.818 143.388 138.124 1.00 60.10  ? 362 HIS C CA  1 
ATOM 6262 C C   . HIS C 3 362 ? 102.905 143.685 139.304 1.00 65.13  ? 362 HIS C C   1 
ATOM 6263 O O   . HIS C 3 362 ? 102.988 143.052 140.359 1.00 69.54  ? 362 HIS C O   1 
ATOM 6264 C CB  . HIS C 3 362 ? 103.077 142.488 137.110 1.00 60.64  ? 362 HIS C CB  1 
ATOM 6265 C CG  . HIS C 3 362 ? 103.946 141.837 136.074 1.00 63.45  ? 362 HIS C CG  1 
ATOM 6266 N ND1 . HIS C 3 362 ? 103.471 140.843 135.252 1.00 62.03  ? 362 HIS C ND1 1 
ATOM 6267 C CD2 . HIS C 3 362 ? 105.175 142.152 135.595 1.00 69.87  ? 362 HIS C CD2 1 
ATOM 6268 C CE1 . HIS C 3 362 ? 104.403 140.508 134.381 1.00 66.81  ? 362 HIS C CE1 1 
ATOM 6269 N NE2 . HIS C 3 362 ? 105.454 141.278 134.576 1.00 70.70  ? 362 HIS C NE2 1 
ATOM 6270 N N   . PHE C 3 363 ? 102.029 144.664 139.096 1.00 69.33  ? 363 PHE C N   1 
ATOM 6271 C CA  . PHE C 3 363 ? 101.174 145.244 140.124 1.00 74.56  ? 363 PHE C CA  1 
ATOM 6272 C C   . PHE C 3 363 ? 99.728  144.832 139.885 1.00 75.93  ? 363 PHE C C   1 
ATOM 6273 O O   . PHE C 3 363 ? 99.163  145.144 138.832 1.00 76.67  ? 363 PHE C O   1 
ATOM 6274 C CB  . PHE C 3 363 ? 101.270 146.765 140.093 1.00 78.36  ? 363 PHE C CB  1 
ATOM 6275 C CG  . PHE C 3 363 ? 102.653 147.300 140.275 1.00 77.08  ? 363 PHE C CG  1 
ATOM 6276 C CD1 . PHE C 3 363 ? 103.270 147.252 141.507 1.00 76.01  ? 363 PHE C CD1 1 
ATOM 6277 C CD2 . PHE C 3 363 ? 103.330 147.865 139.211 1.00 77.08  ? 363 PHE C CD2 1 
ATOM 6278 C CE1 . PHE C 3 363 ? 104.532 147.760 141.678 1.00 76.10  ? 363 PHE C CE1 1 
ATOM 6279 C CE2 . PHE C 3 363 ? 104.596 148.371 139.376 1.00 77.28  ? 363 PHE C CE2 1 
ATOM 6280 C CZ  . PHE C 3 363 ? 105.197 148.318 140.612 1.00 77.57  ? 363 PHE C CZ  1 
ATOM 6281 N N   . THR C 3 364 ? 99.125  144.146 140.858 1.00 80.24  ? 364 THR C N   1 
ATOM 6282 C CA  . THR C 3 364 ? 97.709  143.792 140.792 1.00 87.00  ? 364 THR C CA  1 
ATOM 6283 C C   . THR C 3 364 ? 96.988  144.232 142.053 1.00 93.93  ? 364 THR C C   1 
ATOM 6284 O O   . THR C 3 364 ? 97.562  144.207 143.146 1.00 94.34  ? 364 THR C O   1 
ATOM 6285 C CB  . THR C 3 364 ? 97.470  142.288 140.606 1.00 89.52  ? 364 THR C CB  1 
ATOM 6286 O OG1 . THR C 3 364 ? 97.449  141.641 141.886 1.00 91.69  ? 364 THR C OG1 1 
ATOM 6287 C CG2 . THR C 3 364 ? 98.505  141.658 139.713 1.00 84.60  ? 364 THR C CG2 1 
ATOM 6288 N N   . CYS C 3 365 ? 95.724  144.612 141.893 1.00 99.49  ? 365 CYS C N   1 
ATOM 6289 C CA  . CYS C 3 365 ? 94.851  144.934 143.008 1.00 107.64 ? 365 CYS C CA  1 
ATOM 6290 C C   . CYS C 3 365 ? 94.237  143.657 143.577 1.00 110.49 ? 365 CYS C C   1 
ATOM 6291 O O   . CYS C 3 365 ? 94.607  142.538 143.213 1.00 109.03 ? 365 CYS C O   1 
ATOM 6292 C CB  . CYS C 3 365 ? 93.766  145.911 142.559 1.00 109.71 ? 365 CYS C CB  1 
ATOM 6293 S SG  . CYS C 3 365 ? 93.075  146.928 143.876 1.00 118.71 ? 365 CYS C SG  1 
ATOM 6294 N N   . ALA C 3 366 ? 93.284  143.824 144.492 1.00 114.49 ? 366 ALA C N   1 
ATOM 6295 C CA  . ALA C 3 366 ? 92.528  142.690 145.004 1.00 115.74 ? 366 ALA C CA  1 
ATOM 6296 C C   . ALA C 3 366 ? 91.355  142.309 144.110 1.00 115.74 ? 366 ALA C C   1 
ATOM 6297 O O   . ALA C 3 366 ? 90.764  141.244 144.313 1.00 115.28 ? 366 ALA C O   1 
ATOM 6298 C CB  . ALA C 3 366 ? 92.021  142.988 146.418 1.00 113.90 ? 366 ALA C CB  1 
ATOM 6299 N N   . VAL C 3 367 ? 91.008  143.145 143.131 1.00 115.25 ? 367 VAL C N   1 
ATOM 6300 C CA  . VAL C 3 367 ? 89.880  142.905 142.244 1.00 115.01 ? 367 VAL C CA  1 
ATOM 6301 C C   . VAL C 3 367 ? 90.311  142.768 140.790 1.00 111.89 ? 367 VAL C C   1 
ATOM 6302 O O   . VAL C 3 367 ? 89.475  142.850 139.890 1.00 110.10 ? 367 VAL C O   1 
ATOM 6303 C CB  . VAL C 3 367 ? 88.811  144.007 142.392 1.00 114.91 ? 367 VAL C CB  1 
ATOM 6304 C CG1 . VAL C 3 367 ? 88.232  144.002 143.798 1.00 112.04 ? 367 VAL C CG1 1 
ATOM 6305 C CG2 . VAL C 3 367 ? 89.404  145.370 142.063 1.00 111.58 ? 367 VAL C CG2 1 
ATOM 6306 N N   . ASP C 3 368 ? 91.600  142.564 140.541 1.00 108.62 ? 368 ASP C N   1 
ATOM 6307 C CA  . ASP C 3 368 ? 92.083  142.402 139.179 1.00 102.82 ? 368 ASP C CA  1 
ATOM 6308 C C   . ASP C 3 368 ? 91.653  141.055 138.610 1.00 99.40  ? 368 ASP C C   1 
ATOM 6309 O O   . ASP C 3 368 ? 91.405  140.095 139.344 1.00 103.90 ? 368 ASP C O   1 
ATOM 6310 C CB  . ASP C 3 368 ? 93.606  142.528 139.135 1.00 100.23 ? 368 ASP C CB  1 
ATOM 6311 N N   . THR C 3 369 ? 91.560  140.993 137.282 1.00 92.17  ? 369 THR C N   1 
ATOM 6312 C CA  . THR C 3 369 ? 91.172  139.776 136.589 1.00 89.91  ? 369 THR C CA  1 
ATOM 6313 C C   . THR C 3 369 ? 92.135  139.358 135.490 1.00 85.56  ? 369 THR C C   1 
ATOM 6314 O O   . THR C 3 369 ? 91.993  138.252 134.959 1.00 82.65  ? 369 THR C O   1 
ATOM 6315 C CB  . THR C 3 369 ? 89.769  139.932 135.983 1.00 92.01  ? 369 THR C CB  1 
ATOM 6316 O OG1 . THR C 3 369 ? 89.596  141.276 135.518 1.00 92.57  ? 369 THR C OG1 1 
ATOM 6317 C CG2 . THR C 3 369 ? 88.703  139.617 137.020 1.00 93.41  ? 369 THR C CG2 1 
ATOM 6318 N N   . GLU C 3 370 ? 93.106  140.193 135.138 1.00 86.60  ? 370 GLU C N   1 
ATOM 6319 C CA  . GLU C 3 370 ? 94.030  139.907 134.051 1.00 86.21  ? 370 GLU C CA  1 
ATOM 6320 C C   . GLU C 3 370 ? 95.262  139.140 134.508 1.00 83.70  ? 370 GLU C C   1 
ATOM 6321 O O   . GLU C 3 370 ? 96.209  138.993 133.725 1.00 81.28  ? 370 GLU C O   1 
ATOM 6322 C CB  . GLU C 3 370 ? 94.455  141.208 133.369 1.00 91.92  ? 370 GLU C CB  1 
ATOM 6323 C CG  . GLU C 3 370 ? 94.663  142.371 134.324 1.00 94.51  ? 370 GLU C CG  1 
ATOM 6324 C CD  . GLU C 3 370 ? 93.494  143.336 134.332 1.00 104.07 ? 370 GLU C CD  1 
ATOM 6325 O OE1 . GLU C 3 370 ? 92.342  142.876 134.476 1.00 105.31 ? 370 GLU C OE1 1 
ATOM 6326 O OE2 . GLU C 3 370 ? 93.727  144.556 134.194 1.00 109.45 ? 370 GLU C OE2 1 
ATOM 6327 N N   . ASN C 3 371 ? 95.274  138.656 135.753 1.00 84.32  ? 371 ASN C N   1 
ATOM 6328 C CA  . ASN C 3 371 ? 96.438  137.940 136.266 1.00 79.67  ? 371 ASN C CA  1 
ATOM 6329 C C   . ASN C 3 371 ? 96.649  136.612 135.555 1.00 74.42  ? 371 ASN C C   1 
ATOM 6330 O O   . ASN C 3 371 ? 97.791  136.156 135.439 1.00 75.13  ? 371 ASN C O   1 
ATOM 6331 C CB  . ASN C 3 371 ? 96.297  137.721 137.769 1.00 82.08  ? 371 ASN C CB  1 
ATOM 6332 C CG  . ASN C 3 371 ? 95.773  138.943 138.485 1.00 86.18  ? 371 ASN C CG  1 
ATOM 6333 O OD1 . ASN C 3 371 ? 95.894  140.062 137.991 1.00 86.76  ? 371 ASN C OD1 1 
ATOM 6334 N ND2 . ASN C 3 371 ? 95.184  138.736 139.655 1.00 88.47  ? 371 ASN C ND2 1 
ATOM 6335 N N   . ILE C 3 372 ? 95.577  135.997 135.053 1.00 71.91  ? 372 ILE C N   1 
ATOM 6336 C CA  . ILE C 3 372 ? 95.707  134.751 134.297 1.00 71.24  ? 372 ILE C CA  1 
ATOM 6337 C C   . ILE C 3 372 ? 96.485  134.991 133.008 1.00 73.38  ? 372 ILE C C   1 
ATOM 6338 O O   . ILE C 3 372 ? 97.465  134.295 132.715 1.00 75.87  ? 372 ILE C O   1 
ATOM 6339 C CB  . ILE C 3 372 ? 94.325  134.136 133.995 1.00 78.33  ? 372 ILE C CB  1 
ATOM 6340 C CG1 . ILE C 3 372 ? 93.443  133.892 135.236 1.00 85.51  ? 372 ILE C CG1 1 
ATOM 6341 C CG2 . ILE C 3 372 ? 94.484  132.835 133.219 1.00 77.45  ? 372 ILE C CG2 1 
ATOM 6342 C CD1 . ILE C 3 372 ? 94.141  133.592 136.551 1.00 90.80  ? 372 ILE C CD1 1 
ATOM 6343 N N   . ARG C 3 373 ? 96.072  135.999 132.233 1.00 71.44  ? 373 ARG C N   1 
ATOM 6344 C CA  . ARG C 3 373 ? 96.769  136.319 130.993 1.00 70.90  ? 373 ARG C CA  1 
ATOM 6345 C C   . ARG C 3 373 ? 98.163  136.860 131.263 1.00 71.32  ? 373 ARG C C   1 
ATOM 6346 O O   . ARG C 3 373 ? 99.074  136.675 130.447 1.00 74.74  ? 373 ARG C O   1 
ATOM 6347 C CB  . ARG C 3 373 ? 95.962  137.330 130.178 1.00 69.50  ? 373 ARG C CB  1 
ATOM 6348 C CG  . ARG C 3 373 ? 94.641  136.802 129.651 1.00 74.46  ? 373 ARG C CG  1 
ATOM 6349 C CD  . ARG C 3 373 ? 94.844  135.574 128.787 1.00 78.45  ? 373 ARG C CD  1 
ATOM 6350 N NE  . ARG C 3 373 ? 95.839  135.795 127.745 1.00 80.36  ? 373 ARG C NE  1 
ATOM 6351 C CZ  . ARG C 3 373 ? 95.572  136.295 126.546 1.00 83.47  ? 373 ARG C CZ  1 
ATOM 6352 N NH1 . ARG C 3 373 ? 94.343  136.641 126.199 1.00 87.19  ? 373 ARG C NH1 1 
ATOM 6353 N NH2 . ARG C 3 373 ? 96.563  136.451 125.674 1.00 83.31  ? 373 ARG C NH2 1 
ATOM 6354 N N   . ARG C 3 374 ? 98.352  137.504 132.411 1.00 70.40  ? 374 ARG C N   1 
ATOM 6355 C CA  . ARG C 3 374 ? 99.657  138.058 132.741 1.00 67.42  ? 374 ARG C CA  1 
ATOM 6356 C C   . ARG C 3 374 ? 100.648 136.954 133.102 1.00 64.61  ? 374 ARG C C   1 
ATOM 6357 O O   . ARG C 3 374 ? 101.807 136.985 132.667 1.00 65.79  ? 374 ARG C O   1 
ATOM 6358 C CB  . ARG C 3 374 ? 99.470  139.078 133.859 1.00 66.85  ? 374 ARG C CB  1 
ATOM 6359 C CG  . ARG C 3 374 ? 100.526 140.130 133.951 1.00 64.50  ? 374 ARG C CG  1 
ATOM 6360 C CD  . ARG C 3 374 ? 100.215 141.064 135.103 1.00 64.90  ? 374 ARG C CD  1 
ATOM 6361 N NE  . ARG C 3 374 ? 99.586  142.281 134.608 1.00 65.92  ? 374 ARG C NE  1 
ATOM 6362 C CZ  . ARG C 3 374 ? 98.872  143.117 135.348 1.00 71.08  ? 374 ARG C CZ  1 
ATOM 6363 N NH1 . ARG C 3 374 ? 98.668  142.899 136.633 1.00 73.75  ? 374 ARG C NH1 1 
ATOM 6364 N NH2 . ARG C 3 374 ? 98.348  144.199 134.780 1.00 75.08  ? 374 ARG C NH2 1 
ATOM 6365 N N   . VAL C 3 375 ? 100.192 135.941 133.842 1.00 63.59  ? 375 VAL C N   1 
ATOM 6366 C CA  . VAL C 3 375 ? 101.010 134.762 134.115 1.00 59.28  ? 375 VAL C CA  1 
ATOM 6367 C C   . VAL C 3 375 ? 101.263 133.975 132.831 1.00 62.22  ? 375 VAL C C   1 
ATOM 6368 O O   . VAL C 3 375 ? 102.355 133.424 132.628 1.00 66.38  ? 375 VAL C O   1 
ATOM 6369 C CB  . VAL C 3 375 ? 100.328 133.917 135.209 1.00 63.22  ? 375 VAL C CB  1 
ATOM 6370 C CG1 . VAL C 3 375 ? 100.714 132.444 135.140 1.00 67.39  ? 375 VAL C CG1 1 
ATOM 6371 C CG2 . VAL C 3 375 ? 100.645 134.487 136.579 1.00 61.39  ? 375 VAL C CG2 1 
ATOM 6372 N N   . PHE C 3 376 ? 100.269 133.936 131.937 1.00 64.22  ? 376 PHE C N   1 
ATOM 6373 C CA  . PHE C 3 376 ? 100.436 133.329 130.616 1.00 63.52  ? 376 PHE C CA  1 
ATOM 6374 C C   . PHE C 3 376 ? 101.570 133.987 129.838 1.00 61.83  ? 376 PHE C C   1 
ATOM 6375 O O   . PHE C 3 376 ? 102.469 133.306 129.321 1.00 66.37  ? 376 PHE C O   1 
ATOM 6376 C CB  . PHE C 3 376 ? 99.123  133.455 129.846 1.00 64.03  ? 376 PHE C CB  1 
ATOM 6377 C CG  . PHE C 3 376 ? 99.044  132.611 128.618 1.00 66.34  ? 376 PHE C CG  1 
ATOM 6378 C CD1 . PHE C 3 376 ? 99.076  133.196 127.367 1.00 68.92  ? 376 PHE C CD1 1 
ATOM 6379 C CD2 . PHE C 3 376 ? 98.887  131.244 128.707 1.00 67.68  ? 376 PHE C CD2 1 
ATOM 6380 C CE1 . PHE C 3 376 ? 98.988  132.430 126.227 1.00 69.65  ? 376 PHE C CE1 1 
ATOM 6381 C CE2 . PHE C 3 376 ? 98.787  130.473 127.570 1.00 68.84  ? 376 PHE C CE2 1 
ATOM 6382 C CZ  . PHE C 3 376 ? 98.845  131.066 126.329 1.00 68.58  ? 376 PHE C CZ  1 
ATOM 6383 N N   . ASN C 3 377 ? 101.551 135.319 129.768 1.00 59.77  ? 377 ASN C N   1 
ATOM 6384 C CA  . ASN C 3 377 ? 102.592 136.049 129.055 1.00 60.30  ? 377 ASN C CA  1 
ATOM 6385 C C   . ASN C 3 377 ? 103.947 135.867 129.723 1.00 63.09  ? 377 ASN C C   1 
ATOM 6386 O O   . ASN C 3 377 ? 104.974 135.764 129.042 1.00 64.78  ? 377 ASN C O   1 
ATOM 6387 C CB  . ASN C 3 377 ? 102.234 137.531 128.975 1.00 59.30  ? 377 ASN C CB  1 
ATOM 6388 C CG  . ASN C 3 377 ? 101.074 137.799 128.044 1.00 61.77  ? 377 ASN C CG  1 
ATOM 6389 O OD1 . ASN C 3 377 ? 100.682 136.941 127.256 1.00 66.85  ? 377 ASN C OD1 1 
ATOM 6390 N ND2 . ASN C 3 377 ? 100.518 139.000 128.127 1.00 61.94  ? 377 ASN C ND2 1 
ATOM 6391 N N   . ASP C 3 378 ? 103.968 135.807 131.055 1.00 65.30  ? 378 ASP C N   1 
ATOM 6392 C CA  . ASP C 3 378 ? 105.229 135.626 131.765 1.00 62.89  ? 378 ASP C CA  1 
ATOM 6393 C C   . ASP C 3 378 ? 105.838 134.258 131.506 1.00 59.77  ? 378 ASP C C   1 
ATOM 6394 O O   . ASP C 3 378 ? 107.056 134.143 131.335 1.00 62.39  ? 378 ASP C O   1 
ATOM 6395 C CB  . ASP C 3 378 ? 105.007 135.829 133.251 1.00 65.83  ? 378 ASP C CB  1 
ATOM 6396 C CG  . ASP C 3 378 ? 104.804 137.263 133.593 1.00 67.51  ? 378 ASP C CG  1 
ATOM 6397 O OD1 . ASP C 3 378 ? 104.812 138.089 132.657 1.00 69.66  ? 378 ASP C OD1 1 
ATOM 6398 O OD2 . ASP C 3 378 ? 104.618 137.555 134.784 1.00 68.20  ? 378 ASP C OD2 1 
ATOM 6399 N N   . CYS C 3 379 ? 105.015 133.211 131.481 1.00 59.74  ? 379 CYS C N   1 
ATOM 6400 C CA  . CYS C 3 379 ? 105.526 131.889 131.143 1.00 61.45  ? 379 CYS C CA  1 
ATOM 6401 C C   . CYS C 3 379 ? 105.992 131.831 129.697 1.00 60.52  ? 379 CYS C C   1 
ATOM 6402 O O   . CYS C 3 379 ? 106.969 131.132 129.388 1.00 61.30  ? 379 CYS C O   1 
ATOM 6403 C CB  . CYS C 3 379 ? 104.461 130.827 131.403 1.00 68.16  ? 379 CYS C CB  1 
ATOM 6404 S SG  . CYS C 3 379 ? 104.562 130.047 133.027 1.00 87.65  ? 379 CYS C SG  1 
ATOM 6405 N N   . ARG C 3 380 ? 105.315 132.567 128.808 1.00 58.58  ? 380 ARG C N   1 
ATOM 6406 C CA  . ARG C 3 380 ? 105.759 132.662 127.421 1.00 55.57  ? 380 ARG C CA  1 
ATOM 6407 C C   . ARG C 3 380 ? 107.151 133.277 127.330 1.00 56.00  ? 380 ARG C C   1 
ATOM 6408 O O   . ARG C 3 380 ? 108.043 132.730 126.666 1.00 60.60  ? 380 ARG C O   1 
ATOM 6409 C CB  . ARG C 3 380 ? 104.754 133.478 126.613 1.00 56.62  ? 380 ARG C CB  1 
ATOM 6410 C CG  . ARG C 3 380 ? 105.228 133.865 125.235 1.00 58.03  ? 380 ARG C CG  1 
ATOM 6411 C CD  . ARG C 3 380 ? 104.057 134.207 124.342 1.00 60.05  ? 380 ARG C CD  1 
ATOM 6412 N NE  . ARG C 3 380 ? 103.384 135.421 124.782 1.00 64.81  ? 380 ARG C NE  1 
ATOM 6413 C CZ  . ARG C 3 380 ? 102.123 135.718 124.503 1.00 70.97  ? 380 ARG C CZ  1 
ATOM 6414 N NH1 . ARG C 3 380 ? 101.364 134.905 123.788 1.00 72.41  ? 380 ARG C NH1 1 
ATOM 6415 N NH2 . ARG C 3 380 ? 101.611 136.860 124.952 1.00 74.27  ? 380 ARG C NH2 1 
ATOM 6416 N N   . ASP C 3 381 ? 107.367 134.395 128.029 1.00 55.23  ? 381 ASP C N   1 
ATOM 6417 C CA  . ASP C 3 381 ? 108.690 135.016 128.027 1.00 53.78  ? 381 ASP C CA  1 
ATOM 6418 C C   . ASP C 3 381 ? 109.734 134.165 128.737 1.00 55.13  ? 381 ASP C C   1 
ATOM 6419 O O   . ASP C 3 381 ? 110.907 134.200 128.355 1.00 59.08  ? 381 ASP C O   1 
ATOM 6420 C CB  . ASP C 3 381 ? 108.644 136.415 128.640 1.00 61.11  ? 381 ASP C CB  1 
ATOM 6421 C CG  . ASP C 3 381 ? 107.468 137.229 128.152 1.00 71.66  ? 381 ASP C CG  1 
ATOM 6422 O OD1 . ASP C 3 381 ? 106.838 136.823 127.153 1.00 71.96  ? 381 ASP C OD1 1 
ATOM 6423 O OD2 . ASP C 3 381 ? 107.169 138.274 128.768 1.00 75.75  ? 381 ASP C OD2 1 
ATOM 6424 N N   . ILE C 3 382 ? 109.338 133.386 129.744 1.00 53.12  ? 382 ILE C N   1 
ATOM 6425 C CA  . ILE C 3 382 ? 110.294 132.520 130.431 1.00 51.45  ? 382 ILE C CA  1 
ATOM 6426 C C   . ILE C 3 382 ? 110.783 131.416 129.505 1.00 52.80  ? 382 ILE C C   1 
ATOM 6427 O O   . ILE C 3 382 ? 111.993 131.159 129.405 1.00 56.84  ? 382 ILE C O   1 
ATOM 6428 C CB  . ILE C 3 382 ? 109.675 131.958 131.723 1.00 54.77  ? 382 ILE C CB  1 
ATOM 6429 C CG1 . ILE C 3 382 ? 109.827 132.979 132.838 1.00 57.98  ? 382 ILE C CG1 1 
ATOM 6430 C CG2 . ILE C 3 382 ? 110.340 130.659 132.149 1.00 55.03  ? 382 ILE C CG2 1 
ATOM 6431 C CD1 . ILE C 3 382 ? 111.265 133.378 133.033 1.00 59.85  ? 382 ILE C CD1 1 
ATOM 6432 N N   . ILE C 3 383 ? 109.856 130.766 128.798 1.00 50.15  ? 383 ILE C N   1 
ATOM 6433 C CA  . ILE C 3 383 ? 110.238 129.705 127.871 1.00 49.98  ? 383 ILE C CA  1 
ATOM 6434 C C   . ILE C 3 383 ? 111.067 130.277 126.729 1.00 49.66  ? 383 ILE C C   1 
ATOM 6435 O O   . ILE C 3 383 ? 112.076 129.685 126.315 1.00 55.08  ? 383 ILE C O   1 
ATOM 6436 C CB  . ILE C 3 383 ? 108.984 128.964 127.370 1.00 52.56  ? 383 ILE C CB  1 
ATOM 6437 C CG1 . ILE C 3 383 ? 108.368 128.110 128.484 1.00 57.50  ? 383 ILE C CG1 1 
ATOM 6438 C CG2 . ILE C 3 383 ? 109.310 128.057 126.195 1.00 56.92  ? 383 ILE C CG2 1 
ATOM 6439 C CD1 . ILE C 3 383 ? 109.367 127.446 129.422 1.00 60.29  ? 383 ILE C CD1 1 
ATOM 6440 N N   . GLN C 3 384 ? 110.692 131.466 126.245 1.00 45.17  ? 384 GLN C N   1 
ATOM 6441 C CA  . GLN C 3 384 ? 111.440 132.106 125.168 1.00 42.61  ? 384 GLN C CA  1 
ATOM 6442 C C   . GLN C 3 384 ? 112.853 132.479 125.600 1.00 45.67  ? 384 GLN C C   1 
ATOM 6443 O O   . GLN C 3 384 ? 113.804 132.291 124.835 1.00 52.10  ? 384 GLN C O   1 
ATOM 6444 C CB  . GLN C 3 384 ? 110.692 133.338 124.676 1.00 41.20  ? 384 GLN C CB  1 
ATOM 6445 C CG  . GLN C 3 384 ? 109.553 133.021 123.750 1.00 42.35  ? 384 GLN C CG  1 
ATOM 6446 C CD  . GLN C 3 384 ? 108.847 134.257 123.260 1.00 47.28  ? 384 GLN C CD  1 
ATOM 6447 O OE1 . GLN C 3 384 ? 109.268 135.376 123.542 1.00 51.02  ? 384 GLN C OE1 1 
ATOM 6448 N NE2 . GLN C 3 384 ? 107.762 134.066 122.524 1.00 51.16  ? 384 GLN C NE2 1 
ATOM 6449 N N   . ARG C 3 385 ? 113.017 132.999 126.816 1.00 43.80  ? 385 ARG C N   1 
ATOM 6450 C CA  . ARG C 3 385 ? 114.345 133.394 127.271 1.00 44.53  ? 385 ARG C CA  1 
ATOM 6451 C C   . ARG C 3 385 ? 115.224 132.183 127.537 1.00 50.28  ? 385 ARG C C   1 
ATOM 6452 O O   . ARG C 3 385 ? 116.430 132.220 127.264 1.00 55.28  ? 385 ARG C O   1 
ATOM 6453 C CB  . ARG C 3 385 ? 114.240 134.258 128.522 1.00 48.84  ? 385 ARG C CB  1 
ATOM 6454 C CG  . ARG C 3 385 ? 114.130 135.733 128.239 1.00 52.67  ? 385 ARG C CG  1 
ATOM 6455 C CD  . ARG C 3 385 ? 113.987 136.511 129.523 1.00 53.35  ? 385 ARG C CD  1 
ATOM 6456 N NE  . ARG C 3 385 ? 113.122 137.670 129.366 1.00 59.21  ? 385 ARG C NE  1 
ATOM 6457 C CZ  . ARG C 3 385 ? 113.118 138.709 130.188 1.00 64.50  ? 385 ARG C CZ  1 
ATOM 6458 N NH1 . ARG C 3 385 ? 113.924 138.763 131.233 1.00 66.06  ? 385 ARG C NH1 1 
ATOM 6459 N NH2 . ARG C 3 385 ? 112.280 139.715 129.957 1.00 61.56  ? 385 ARG C NH2 1 
ATOM 6460 N N   . MET C 3 386 ? 114.642 131.103 128.068 1.00 52.46  ? 386 MET C N   1 
ATOM 6461 C CA  . MET C 3 386 ? 115.404 129.874 128.277 1.00 51.74  ? 386 MET C CA  1 
ATOM 6462 C C   . MET C 3 386 ? 115.870 129.304 126.941 1.00 53.84  ? 386 MET C C   1 
ATOM 6463 O O   . MET C 3 386 ? 117.042 128.926 126.790 1.00 59.11  ? 386 MET C O   1 
ATOM 6464 C CB  . MET C 3 386 ? 114.531 128.879 129.050 1.00 55.26  ? 386 MET C CB  1 
ATOM 6465 C CG  . MET C 3 386 ? 114.893 127.388 129.061 1.00 66.38  ? 386 MET C CG  1 
ATOM 6466 S SD  . MET C 3 386 ? 116.626 126.894 129.178 1.00 84.99  ? 386 MET C SD  1 
ATOM 6467 C CE  . MET C 3 386 ? 116.648 125.542 128.010 1.00 72.45  ? 386 MET C CE  1 
ATOM 6468 N N   . HIS C 3 387 ? 114.983 129.294 125.942 1.00 53.53  ? 387 HIS C N   1 
ATOM 6469 C CA  . HIS C 3 387 ? 115.360 128.812 124.618 1.00 52.57  ? 387 HIS C CA  1 
ATOM 6470 C C   . HIS C 3 387 ? 116.404 129.710 123.965 1.00 55.02  ? 387 HIS C C   1 
ATOM 6471 O O   . HIS C 3 387 ? 117.321 129.215 123.300 1.00 62.54  ? 387 HIS C O   1 
ATOM 6472 C CB  . HIS C 3 387 ? 114.127 128.700 123.729 1.00 54.16  ? 387 HIS C CB  1 
ATOM 6473 C CG  . HIS C 3 387 ? 113.255 127.532 124.055 1.00 61.75  ? 387 HIS C CG  1 
ATOM 6474 N ND1 . HIS C 3 387 ? 112.030 127.329 123.460 1.00 67.31  ? 387 HIS C ND1 1 
ATOM 6475 C CD2 . HIS C 3 387 ? 113.431 126.501 124.915 1.00 60.50  ? 387 HIS C CD2 1 
ATOM 6476 C CE1 . HIS C 3 387 ? 111.488 126.225 123.939 1.00 67.29  ? 387 HIS C CE1 1 
ATOM 6477 N NE2 . HIS C 3 387 ? 112.317 125.703 124.824 1.00 66.08  ? 387 HIS C NE2 1 
ATOM 6478 N N   . LEU C 3 388 ? 116.287 131.026 124.145 1.00 52.83  ? 388 LEU C N   1 
ATOM 6479 C CA  . LEU C 3 388 ? 117.238 131.948 123.536 1.00 51.22  ? 388 LEU C CA  1 
ATOM 6480 C C   . LEU C 3 388 ? 118.605 131.846 124.191 1.00 54.93  ? 388 LEU C C   1 
ATOM 6481 O O   . LEU C 3 388 ? 119.631 132.016 123.523 1.00 62.49  ? 388 LEU C O   1 
ATOM 6482 C CB  . LEU C 3 388 ? 116.709 133.375 123.621 1.00 51.31  ? 388 LEU C CB  1 
ATOM 6483 C CG  . LEU C 3 388 ? 115.802 133.806 122.473 1.00 52.55  ? 388 LEU C CG  1 
ATOM 6484 C CD1 . LEU C 3 388 ? 115.425 135.264 122.619 1.00 52.32  ? 388 LEU C CD1 1 
ATOM 6485 C CD2 . LEU C 3 388 ? 116.490 133.554 121.151 1.00 55.33  ? 388 LEU C CD2 1 
ATOM 6486 N N   . ARG C 3 389 ? 118.643 131.583 125.495 1.00 53.75  ? 389 ARG C N   1 
ATOM 6487 C CA  . ARG C 3 389 ? 119.921 131.344 126.150 1.00 57.77  ? 389 ARG C CA  1 
ATOM 6488 C C   . ARG C 3 389 ? 120.526 130.017 125.718 1.00 59.77  ? 389 ARG C C   1 
ATOM 6489 O O   . ARG C 3 389 ? 121.752 129.895 125.646 1.00 63.49  ? 389 ARG C O   1 
ATOM 6490 C CB  . ARG C 3 389 ? 119.754 131.386 127.666 1.00 62.48  ? 389 ARG C CB  1 
ATOM 6491 C CG  . ARG C 3 389 ? 120.158 132.703 128.287 1.00 65.28  ? 389 ARG C CG  1 
ATOM 6492 C CD  . ARG C 3 389 ? 121.623 132.695 128.674 1.00 71.63  ? 389 ARG C CD  1 
ATOM 6493 N NE  . ARG C 3 389 ? 121.876 131.817 129.809 1.00 77.06  ? 389 ARG C NE  1 
ATOM 6494 C CZ  . ARG C 3 389 ? 122.569 130.689 129.744 1.00 81.10  ? 389 ARG C CZ  1 
ATOM 6495 N NH1 . ARG C 3 389 ? 123.096 130.267 128.607 1.00 81.60  ? 389 ARG C NH1 1 
ATOM 6496 N NH2 . ARG C 3 389 ? 122.739 129.967 130.848 1.00 80.51  ? 389 ARG C NH2 1 
ATOM 6497 N N   . GLN C 3 390 ? 119.693 129.013 125.430 1.00 59.98  ? 390 GLN C N   1 
ATOM 6498 C CA  . GLN C 3 390 ? 120.234 127.773 124.886 1.00 59.68  ? 390 GLN C CA  1 
ATOM 6499 C C   . GLN C 3 390 ? 120.674 127.916 123.436 1.00 58.97  ? 390 GLN C C   1 
ATOM 6500 O O   . GLN C 3 390 ? 121.407 127.056 122.939 1.00 61.55  ? 390 GLN C O   1 
ATOM 6501 C CB  . GLN C 3 390 ? 119.219 126.638 124.994 1.00 63.89  ? 390 GLN C CB  1 
ATOM 6502 C CG  . GLN C 3 390 ? 119.785 125.382 125.623 1.00 69.04  ? 390 GLN C CG  1 
ATOM 6503 C CD  . GLN C 3 390 ? 118.806 124.227 125.603 1.00 79.08  ? 390 GLN C CD  1 
ATOM 6504 O OE1 . GLN C 3 390 ? 117.903 124.178 124.768 1.00 82.16  ? 390 GLN C OE1 1 
ATOM 6505 N NE2 . GLN C 3 390 ? 118.977 123.290 126.528 1.00 80.61  ? 390 GLN C NE2 1 
ATOM 6506 N N   . TYR C 3 391 ? 120.242 128.967 122.747 1.00 59.26  ? 391 TYR C N   1 
ATOM 6507 C CA  . TYR C 3 391 ? 120.659 129.223 121.377 1.00 57.85  ? 391 TYR C CA  1 
ATOM 6508 C C   . TYR C 3 391 ? 121.853 130.158 121.293 1.00 59.82  ? 391 TYR C C   1 
ATOM 6509 O O   . TYR C 3 391 ? 122.277 130.488 120.180 1.00 59.51  ? 391 TYR C O   1 
ATOM 6510 C CB  . TYR C 3 391 ? 119.502 129.815 120.568 1.00 55.31  ? 391 TYR C CB  1 
ATOM 6511 C CG  . TYR C 3 391 ? 118.328 128.888 120.375 1.00 59.12  ? 391 TYR C CG  1 
ATOM 6512 C CD1 . TYR C 3 391 ? 118.480 127.512 120.462 1.00 62.65  ? 391 TYR C CD1 1 
ATOM 6513 C CD2 . TYR C 3 391 ? 117.065 129.390 120.104 1.00 61.54  ? 391 TYR C CD2 1 
ATOM 6514 C CE1 . TYR C 3 391 ? 117.408 126.664 120.288 1.00 66.58  ? 391 TYR C CE1 1 
ATOM 6515 C CE2 . TYR C 3 391 ? 115.986 128.550 119.931 1.00 65.72  ? 391 TYR C CE2 1 
ATOM 6516 C CZ  . TYR C 3 391 ? 116.164 127.188 120.021 1.00 66.95  ? 391 TYR C CZ  1 
ATOM 6517 O OH  . TYR C 3 391 ? 115.093 126.344 119.846 1.00 70.12  ? 391 TYR C OH  1 
ATOM 6518 N N   . GLU C 3 392 ? 122.390 130.586 122.441 1.00 63.24  ? 392 GLU C N   1 
ATOM 6519 C CA  . GLU C 3 392 ? 123.475 131.573 122.535 1.00 64.17  ? 392 GLU C CA  1 
ATOM 6520 C C   . GLU C 3 392 ? 123.127 132.863 121.797 1.00 64.40  ? 392 GLU C C   1 
ATOM 6521 O O   . GLU C 3 392 ? 123.982 133.503 121.182 1.00 69.69  ? 392 GLU C O   1 
ATOM 6522 C CB  . GLU C 3 392 ? 124.815 131.010 122.038 1.00 69.33  ? 392 GLU C CB  1 
ATOM 6523 C CG  . GLU C 3 392 ? 125.151 129.546 122.362 1.00 76.15  ? 392 GLU C CG  1 
ATOM 6524 C CD  . GLU C 3 392 ? 124.784 129.126 123.775 1.00 80.42  ? 392 GLU C CD  1 
ATOM 6525 O OE1 . GLU C 3 392 ? 125.609 129.335 124.689 1.00 85.32  ? 392 GLU C OE1 1 
ATOM 6526 O OE2 . GLU C 3 392 ? 123.686 128.568 123.967 1.00 77.77  ? 392 GLU C OE2 1 
ATOM 6527 N N   . LEU C 3 393 ? 121.858 133.254 121.865 1.00 63.87  ? 393 LEU C N   1 
ATOM 6528 C CA  . LEU C 3 393 ? 121.362 134.431 121.168 1.00 67.13  ? 393 LEU C CA  1 
ATOM 6529 C C   . LEU C 3 393 ? 121.080 135.598 122.100 1.00 72.67  ? 393 LEU C C   1 
ATOM 6530 O O   . LEU C 3 393 ? 120.677 136.667 121.630 1.00 75.18  ? 393 LEU C O   1 
ATOM 6531 C CB  . LEU C 3 393 ? 120.094 134.076 120.383 1.00 66.89  ? 393 LEU C CB  1 
ATOM 6532 C CG  . LEU C 3 393 ? 119.783 134.791 119.067 1.00 69.92  ? 393 LEU C CG  1 
ATOM 6533 C CD1 . LEU C 3 393 ? 121.048 135.180 118.325 1.00 70.18  ? 393 LEU C CD1 1 
ATOM 6534 C CD2 . LEU C 3 393 ? 118.902 133.916 118.195 1.00 69.95  ? 393 LEU C CD2 1 
ATOM 6535 N N   . LEU C 3 394 ? 121.281 135.430 123.401 1.00 77.50  ? 394 LEU C N   1 
ATOM 6536 C CA  . LEU C 3 394 ? 121.008 136.493 124.358 1.00 83.29  ? 394 LEU C CA  1 
ATOM 6537 C C   . LEU C 3 394 ? 121.927 136.386 125.570 1.00 93.01  ? 394 LEU C C   1 
ATOM 6538 O O   . LEU C 3 394 ? 122.272 135.288 126.007 1.00 94.25  ? 394 LEU C O   1 
ATOM 6539 C CB  . LEU C 3 394 ? 119.545 136.448 124.796 1.00 76.86  ? 394 LEU C CB  1 
ATOM 6540 C CG  . LEU C 3 394 ? 119.036 137.619 125.632 1.00 79.33  ? 394 LEU C CG  1 
ATOM 6541 C CD1 . LEU C 3 394 ? 117.865 138.295 124.943 1.00 79.22  ? 394 LEU C CD1 1 
ATOM 6542 C CD2 . LEU C 3 394 ? 118.645 137.146 127.016 1.00 82.80  ? 394 LEU C CD2 1 
ATOM 6543 O OXT . LEU C 3 394 ? 122.345 137.392 126.144 1.00 95.36  ? 394 LEU C OXT 1 
ATOM 6544 N N   . ASN D 4 5   ? 103.877 132.321 179.712 1.00 174.18 ? 5   ASN G N   1 
ATOM 6545 C CA  . ASN D 4 5   ? 105.058 131.781 179.050 1.00 176.99 ? 5   ASN G CA  1 
ATOM 6546 C C   . ASN D 4 5   ? 105.414 130.407 179.606 1.00 175.56 ? 5   ASN G C   1 
ATOM 6547 O O   . ASN D 4 5   ? 106.548 130.170 180.023 1.00 174.56 ? 5   ASN G O   1 
ATOM 6548 C CB  . ASN D 4 5   ? 106.244 132.737 179.207 1.00 175.12 ? 5   ASN G CB  1 
ATOM 6549 N N   . THR D 4 6   ? 104.434 129.501 179.613 1.00 175.33 ? 6   THR G N   1 
ATOM 6550 C CA  . THR D 4 6   ? 104.658 128.159 180.134 1.00 171.74 ? 6   THR G CA  1 
ATOM 6551 C C   . THR D 4 6   ? 105.325 127.234 179.124 1.00 168.16 ? 6   THR G C   1 
ATOM 6552 O O   . THR D 4 6   ? 105.816 126.167 179.513 1.00 163.11 ? 6   THR G O   1 
ATOM 6553 C CB  . THR D 4 6   ? 103.335 127.548 180.614 1.00 171.52 ? 6   THR G CB  1 
ATOM 6554 O OG1 . THR D 4 6   ? 103.604 126.503 181.557 1.00 168.77 ? 6   THR G OG1 1 
ATOM 6555 C CG2 . THR D 4 6   ? 102.528 126.984 179.449 1.00 170.03 ? 6   THR G CG2 1 
ATOM 6556 N N   . ALA D 4 7   ? 105.370 127.622 177.846 1.00 171.33 ? 7   ALA G N   1 
ATOM 6557 C CA  . ALA D 4 7   ? 105.949 126.754 176.826 1.00 170.98 ? 7   ALA G CA  1 
ATOM 6558 C C   . ALA D 4 7   ? 107.461 126.647 176.980 1.00 170.20 ? 7   ALA G C   1 
ATOM 6559 O O   . ALA D 4 7   ? 108.030 125.561 176.813 1.00 165.44 ? 7   ALA G O   1 
ATOM 6560 C CB  . ALA D 4 7   ? 105.583 127.265 175.433 1.00 166.79 ? 7   ALA G CB  1 
ATOM 6561 N N   . SER D 4 8   ? 108.124 127.762 177.303 1.00 174.72 ? 8   SER G N   1 
ATOM 6562 C CA  . SER D 4 8   ? 109.575 127.748 177.472 1.00 172.93 ? 8   SER G CA  1 
ATOM 6563 C C   . SER D 4 8   ? 109.990 126.903 178.670 1.00 166.16 ? 8   SER G C   1 
ATOM 6564 O O   . SER D 4 8   ? 110.937 126.114 178.579 1.00 162.42 ? 8   SER G O   1 
ATOM 6565 C CB  . SER D 4 8   ? 110.103 129.175 177.614 1.00 173.95 ? 8   SER G CB  1 
ATOM 6566 O OG  . SER D 4 8   ? 109.557 129.812 178.755 1.00 172.95 ? 8   SER G OG  1 
ATOM 6567 N N   . ILE D 4 9   ? 109.285 127.034 179.796 1.00 166.49 ? 9   ILE G N   1 
ATOM 6568 C CA  . ILE D 4 9   ? 109.651 126.238 180.964 1.00 161.76 ? 9   ILE G CA  1 
ATOM 6569 C C   . ILE D 4 9   ? 109.223 124.786 180.788 1.00 152.31 ? 9   ILE G C   1 
ATOM 6570 O O   . ILE D 4 9   ? 109.832 123.883 181.371 1.00 147.75 ? 9   ILE G O   1 
ATOM 6571 C CB  . ILE D 4 9   ? 109.072 126.853 182.250 1.00 161.34 ? 9   ILE G CB  1 
ATOM 6572 C CG1 . ILE D 4 9   ? 107.586 127.151 182.085 1.00 158.00 ? 9   ILE G CG1 1 
ATOM 6573 C CG2 . ILE D 4 9   ? 109.833 128.120 182.617 1.00 160.18 ? 9   ILE G CG2 1 
ATOM 6574 C CD1 . ILE D 4 9   ? 106.925 127.674 183.339 1.00 153.73 ? 9   ILE G CD1 1 
ATOM 6575 N N   . ALA D 4 10  ? 108.194 124.528 179.977 1.00 151.40 ? 10  ALA G N   1 
ATOM 6576 C CA  . ALA D 4 10  ? 107.848 123.148 179.645 1.00 144.81 ? 10  ALA G CA  1 
ATOM 6577 C C   . ALA D 4 10  ? 108.941 122.493 178.812 1.00 139.02 ? 10  ALA G C   1 
ATOM 6578 O O   . ALA D 4 10  ? 109.336 121.345 179.069 1.00 135.64 ? 10  ALA G O   1 
ATOM 6579 C CB  . ALA D 4 10  ? 106.508 123.107 178.912 1.00 146.30 ? 10  ALA G CB  1 
ATOM 6580 N N   . GLN D 4 11  ? 109.436 123.220 177.805 1.00 140.59 ? 11  GLN G N   1 
ATOM 6581 C CA  . GLN D 4 11  ? 110.586 122.769 177.028 1.00 143.48 ? 11  GLN G CA  1 
ATOM 6582 C C   . GLN D 4 11  ? 111.801 122.564 177.923 1.00 142.68 ? 11  GLN G C   1 
ATOM 6583 O O   . GLN D 4 11  ? 112.553 121.597 177.754 1.00 141.35 ? 11  GLN G O   1 
ATOM 6584 C CB  . GLN D 4 11  ? 110.895 123.785 175.926 1.00 149.54 ? 11  GLN G CB  1 
ATOM 6585 C CG  . GLN D 4 11  ? 112.185 123.537 175.154 1.00 151.54 ? 11  GLN G CG  1 
ATOM 6586 C CD  . GLN D 4 11  ? 112.258 122.151 174.548 1.00 147.90 ? 11  GLN G CD  1 
ATOM 6587 O OE1 . GLN D 4 11  ? 111.447 121.791 173.696 1.00 146.56 ? 11  GLN G OE1 1 
ATOM 6588 N NE2 . GLN D 4 11  ? 113.230 121.361 174.990 1.00 144.11 ? 11  GLN G NE2 1 
ATOM 6589 N N   . ALA D 4 12  ? 111.981 123.450 178.905 1.00 146.06 ? 12  ALA G N   1 
ATOM 6590 C CA  . ALA D 4 12  ? 113.088 123.324 179.845 1.00 145.41 ? 12  ALA G CA  1 
ATOM 6591 C C   . ALA D 4 12  ? 112.969 122.060 180.687 1.00 135.70 ? 12  ALA G C   1 
ATOM 6592 O O   . ALA D 4 12  ? 113.959 121.339 180.868 1.00 135.97 ? 12  ALA G O   1 
ATOM 6593 C CB  . ALA D 4 12  ? 113.154 124.560 180.742 1.00 146.08 ? 12  ALA G CB  1 
ATOM 6594 N N   . ARG D 4 13  ? 111.767 121.765 181.200 1.00 129.50 ? 13  ARG G N   1 
ATOM 6595 C CA  . ARG D 4 13  ? 111.616 120.583 182.043 1.00 123.51 ? 13  ARG G CA  1 
ATOM 6596 C C   . ARG D 4 13  ? 111.800 119.306 181.237 1.00 122.57 ? 13  ARG G C   1 
ATOM 6597 O O   . ARG D 4 13  ? 112.461 118.368 181.703 1.00 123.79 ? 13  ARG G O   1 
ATOM 6598 C CB  . ARG D 4 13  ? 110.261 120.553 182.756 1.00 122.62 ? 13  ARG G CB  1 
ATOM 6599 C CG  . ARG D 4 13  ? 110.139 121.499 183.941 1.00 127.48 ? 13  ARG G CG  1 
ATOM 6600 C CD  . ARG D 4 13  ? 108.735 121.668 184.606 1.00 134.58 ? 13  ARG G CD  1 
ATOM 6601 N NE  . ARG D 4 13  ? 107.641 122.350 183.910 1.00 144.57 ? 13  ARG G NE  1 
ATOM 6602 C CZ  . ARG D 4 13  ? 106.944 121.903 182.870 1.00 146.23 ? 13  ARG G CZ  1 
ATOM 6603 N NH1 . ARG D 4 13  ? 107.103 120.681 182.391 1.00 139.39 ? 13  ARG G NH1 1 
ATOM 6604 N NH2 . ARG D 4 13  ? 105.997 122.678 182.350 1.00 150.61 ? 13  ARG G NH2 1 
ATOM 6605 N N   . LYS D 4 14  ? 111.250 119.256 180.018 1.00 122.57 ? 14  LYS G N   1 
ATOM 6606 C CA  . LYS D 4 14  ? 111.421 118.040 179.230 1.00 120.15 ? 14  LYS G CA  1 
ATOM 6607 C C   . LYS D 4 14  ? 112.864 117.875 178.775 1.00 117.28 ? 14  LYS G C   1 
ATOM 6608 O O   . LYS D 4 14  ? 113.362 116.745 178.726 1.00 119.23 ? 14  LYS G O   1 
ATOM 6609 C CB  . LYS D 4 14  ? 110.453 118.004 178.045 1.00 125.23 ? 14  LYS G CB  1 
ATOM 6610 C CG  . LYS D 4 14  ? 110.597 119.108 177.030 1.00 135.94 ? 14  LYS G CG  1 
ATOM 6611 C CD  . LYS D 4 14  ? 110.116 118.661 175.660 1.00 136.78 ? 14  LYS G CD  1 
ATOM 6612 C CE  . LYS D 4 14  ? 109.262 119.735 175.003 1.00 141.85 ? 14  LYS G CE  1 
ATOM 6613 N NZ  . LYS D 4 14  ? 107.902 119.826 175.605 1.00 139.25 ? 14  LYS G NZ  1 
ATOM 6614 N N   . LEU D 4 15  ? 113.571 118.980 178.517 1.00 118.15 ? 15  LEU G N   1 
ATOM 6615 C CA  . LEU D 4 15  ? 114.987 118.891 178.184 1.00 121.61 ? 15  LEU G CA  1 
ATOM 6616 C C   . LEU D 4 15  ? 115.810 118.386 179.362 1.00 117.81 ? 15  LEU G C   1 
ATOM 6617 O O   . LEU D 4 15  ? 116.689 117.532 179.188 1.00 118.31 ? 15  LEU G O   1 
ATOM 6618 C CB  . LEU D 4 15  ? 115.502 120.252 177.718 1.00 130.78 ? 15  LEU G CB  1 
ATOM 6619 C CG  . LEU D 4 15  ? 116.880 120.242 177.053 1.00 130.92 ? 15  LEU G CG  1 
ATOM 6620 C CD1 . LEU D 4 15  ? 116.809 120.881 175.675 1.00 129.64 ? 15  LEU G CD1 1 
ATOM 6621 C CD2 . LEU D 4 15  ? 117.915 120.941 177.923 1.00 126.09 ? 15  LEU G CD2 1 
ATOM 6622 N N   . VAL D 4 16  ? 115.540 118.889 180.572 1.00 118.54 ? 16  VAL G N   1 
ATOM 6623 C CA  . VAL D 4 16  ? 116.374 118.489 181.702 1.00 118.55 ? 16  VAL G CA  1 
ATOM 6624 C C   . VAL D 4 16  ? 116.070 117.057 182.127 1.00 112.74 ? 16  VAL G C   1 
ATOM 6625 O O   . VAL D 4 16  ? 116.983 116.318 182.508 1.00 114.24 ? 16  VAL G O   1 
ATOM 6626 C CB  . VAL D 4 16  ? 116.276 119.483 182.880 1.00 124.60 ? 16  VAL G CB  1 
ATOM 6627 C CG1 . VAL D 4 16  ? 116.776 120.860 182.461 1.00 123.55 ? 16  VAL G CG1 1 
ATOM 6628 C CG2 . VAL D 4 16  ? 114.882 119.557 183.468 1.00 126.91 ? 16  VAL G CG2 1 
ATOM 6629 N N   . GLU D 4 17  ? 114.810 116.606 182.031 1.00 113.02 ? 17  GLU G N   1 
ATOM 6630 C CA  . GLU D 4 17  ? 114.616 115.197 182.365 1.00 114.83 ? 17  GLU G CA  1 
ATOM 6631 C C   . GLU D 4 17  ? 115.073 114.274 181.239 1.00 113.83 ? 17  GLU G C   1 
ATOM 6632 O O   . GLU D 4 17  ? 115.501 113.149 181.520 1.00 114.33 ? 17  GLU G O   1 
ATOM 6633 C CB  . GLU D 4 17  ? 113.172 114.864 182.776 1.00 122.59 ? 17  GLU G CB  1 
ATOM 6634 C CG  . GLU D 4 17  ? 112.110 114.734 181.691 1.00 129.37 ? 17  GLU G CG  1 
ATOM 6635 C CD  . GLU D 4 17  ? 110.756 115.287 182.129 1.00 136.52 ? 17  GLU G CD  1 
ATOM 6636 O OE1 . GLU D 4 17  ? 109.989 114.513 182.742 1.00 141.73 ? 17  GLU G OE1 1 
ATOM 6637 O OE2 . GLU D 4 17  ? 110.435 116.459 181.868 1.00 140.28 ? 17  GLU G OE2 1 
ATOM 6638 N N   . GLN D 4 18  ? 115.037 114.730 179.980 1.00 113.74 ? 18  GLN G N   1 
ATOM 6639 C CA  . GLN D 4 18  ? 115.667 113.984 178.894 1.00 109.64 ? 18  GLN G CA  1 
ATOM 6640 C C   . GLN D 4 18  ? 117.153 113.790 179.145 1.00 105.84 ? 18  GLN G C   1 
ATOM 6641 O O   . GLN D 4 18  ? 117.675 112.673 179.030 1.00 106.68 ? 18  GLN G O   1 
ATOM 6642 C CB  . GLN D 4 18  ? 115.445 114.717 177.570 1.00 113.21 ? 18  GLN G CB  1 
ATOM 6643 C CG  . GLN D 4 18  ? 115.850 114.031 176.232 1.00 113.29 ? 18  GLN G CG  1 
ATOM 6644 C CD  . GLN D 4 18  ? 115.878 112.496 176.157 1.00 119.10 ? 18  GLN G CD  1 
ATOM 6645 O OE1 . GLN D 4 18  ? 115.131 111.772 176.821 1.00 121.02 ? 18  GLN G OE1 1 
ATOM 6646 N NE2 . GLN D 4 18  ? 116.803 111.999 175.352 1.00 121.95 ? 18  GLN G NE2 1 
ATOM 6647 N N   . LEU D 4 19  ? 117.844 114.866 179.526 1.00 105.70 ? 19  LEU G N   1 
ATOM 6648 C CA  . LEU D 4 19  ? 119.257 114.758 179.860 1.00 102.79 ? 19  LEU G CA  1 
ATOM 6649 C C   . LEU D 4 19  ? 119.475 113.915 181.108 1.00 103.34 ? 19  LEU G C   1 
ATOM 6650 O O   . LEU D 4 19  ? 120.507 113.245 181.225 1.00 106.07 ? 19  LEU G O   1 
ATOM 6651 C CB  . LEU D 4 19  ? 119.865 116.148 180.039 1.00 105.08 ? 19  LEU G CB  1 
ATOM 6652 C CG  . LEU D 4 19  ? 120.706 116.705 178.886 1.00 108.19 ? 19  LEU G CG  1 
ATOM 6653 C CD1 . LEU D 4 19  ? 122.098 116.089 178.895 1.00 108.00 ? 19  LEU G CD1 1 
ATOM 6654 C CD2 . LEU D 4 19  ? 120.035 116.490 177.539 1.00 111.97 ? 19  LEU G CD2 1 
ATOM 6655 N N   . LYS D 4 20  ? 118.514 113.923 182.037 1.00 106.35 ? 20  LYS G N   1 
ATOM 6656 C CA  . LYS D 4 20  ? 118.644 113.137 183.259 1.00 113.65 ? 20  LYS G CA  1 
ATOM 6657 C C   . LYS D 4 20  ? 118.620 111.642 182.969 1.00 114.33 ? 20  LYS G C   1 
ATOM 6658 O O   . LYS D 4 20  ? 119.517 110.907 183.398 1.00 114.07 ? 20  LYS G O   1 
ATOM 6659 C CB  . LYS D 4 20  ? 117.532 113.509 184.237 1.00 120.98 ? 20  LYS G CB  1 
ATOM 6660 C CG  . LYS D 4 20  ? 117.943 113.437 185.696 1.00 125.49 ? 20  LYS G CG  1 
ATOM 6661 C CD  . LYS D 4 20  ? 116.790 113.815 186.610 1.00 126.71 ? 20  LYS G CD  1 
ATOM 6662 C CE  . LYS D 4 20  ? 116.314 115.234 186.345 1.00 125.37 ? 20  LYS G CE  1 
ATOM 6663 N NZ  . LYS D 4 20  ? 117.381 116.240 186.605 1.00 127.09 ? 20  LYS G NZ  1 
ATOM 6664 N N   . MET D 4 21  ? 117.608 111.169 182.234 1.00 118.73 ? 21  MET G N   1 
ATOM 6665 C CA  . MET D 4 21  ? 117.595 109.740 181.917 1.00 123.12 ? 21  MET G CA  1 
ATOM 6666 C C   . MET D 4 21  ? 118.603 109.368 180.837 1.00 116.00 ? 21  MET G C   1 
ATOM 6667 O O   . MET D 4 21  ? 118.933 108.186 180.707 1.00 118.81 ? 21  MET G O   1 
ATOM 6668 C CB  . MET D 4 21  ? 116.201 109.232 181.518 1.00 129.13 ? 21  MET G CB  1 
ATOM 6669 C CG  . MET D 4 21  ? 115.025 110.091 181.911 1.00 132.17 ? 21  MET G CG  1 
ATOM 6670 S SD  . MET D 4 21  ? 113.503 109.625 181.064 1.00 148.34 ? 21  MET G SD  1 
ATOM 6671 C CE  . MET D 4 21  ? 113.662 110.563 179.547 1.00 128.55 ? 21  MET G CE  1 
ATOM 6672 N N   . GLU D 4 22  ? 119.107 110.332 180.064 1.00 109.82 ? 22  GLU G N   1 
ATOM 6673 C CA  . GLU D 4 22  ? 120.199 110.009 179.154 1.00 108.96 ? 22  GLU G CA  1 
ATOM 6674 C C   . GLU D 4 22  ? 121.525 109.932 179.902 1.00 108.95 ? 22  GLU G C   1 
ATOM 6675 O O   . GLU D 4 22  ? 122.455 109.265 179.436 1.00 111.22 ? 22  GLU G O   1 
ATOM 6676 C CB  . GLU D 4 22  ? 120.182 111.023 177.989 1.00 112.92 ? 22  GLU G CB  1 
ATOM 6677 C CG  . GLU D 4 22  ? 121.388 111.214 177.016 1.00 115.78 ? 22  GLU G CG  1 
ATOM 6678 C CD  . GLU D 4 22  ? 122.684 111.732 177.627 1.00 124.19 ? 22  GLU G CD  1 
ATOM 6679 O OE1 . GLU D 4 22  ? 122.629 112.741 178.361 1.00 125.43 ? 22  GLU G OE1 1 
ATOM 6680 O OE2 . GLU D 4 22  ? 123.748 111.128 177.374 1.00 125.47 ? 22  GLU G OE2 1 
ATOM 6681 N N   . ALA D 4 23  ? 121.618 110.580 181.065 1.00 109.88 ? 23  ALA G N   1 
ATOM 6682 C CA  . ALA D 4 23  ? 122.886 110.658 181.783 1.00 114.42 ? 23  ALA G CA  1 
ATOM 6683 C C   . ALA D 4 23  ? 123.281 109.319 182.395 1.00 114.17 ? 23  ALA G C   1 
ATOM 6684 O O   . ALA D 4 23  ? 124.424 108.872 182.246 1.00 107.23 ? 23  ALA G O   1 
ATOM 6685 C CB  . ALA D 4 23  ? 122.806 111.737 182.863 1.00 114.26 ? 23  ALA G CB  1 
ATOM 6686 N N   . ASN D 4 24  ? 122.349 108.660 183.082 1.00 118.26 ? 24  ASN G N   1 
ATOM 6687 C CA  . ASN D 4 24  ? 122.663 107.452 183.846 1.00 116.34 ? 24  ASN G CA  1 
ATOM 6688 C C   . ASN D 4 24  ? 122.698 106.243 182.910 1.00 116.16 ? 24  ASN G C   1 
ATOM 6689 O O   . ASN D 4 24  ? 121.815 105.383 182.899 1.00 123.13 ? 24  ASN G O   1 
ATOM 6690 C CB  . ASN D 4 24  ? 121.663 107.262 184.977 1.00 119.44 ? 24  ASN G CB  1 
ATOM 6691 C CG  . ASN D 4 24  ? 120.252 107.627 184.572 1.00 121.83 ? 24  ASN G CG  1 
ATOM 6692 O OD1 . ASN D 4 24  ? 120.004 108.009 183.430 1.00 122.90 ? 24  ASN G OD1 1 
ATOM 6693 N ND2 . ASN D 4 24  ? 119.318 107.512 185.508 1.00 119.71 ? 24  ASN G ND2 1 
ATOM 6694 N N   . ILE D 4 25  ? 123.761 106.193 182.107 1.00 109.90 ? 25  ILE G N   1 
ATOM 6695 C CA  . ILE D 4 25  ? 124.030 105.082 181.207 1.00 109.17 ? 25  ILE G CA  1 
ATOM 6696 C C   . ILE D 4 25  ? 125.484 104.676 181.386 1.00 109.08 ? 25  ILE G C   1 
ATOM 6697 O O   . ILE D 4 25  ? 126.302 105.425 181.924 1.00 110.88 ? 25  ILE G O   1 
ATOM 6698 C CB  . ILE D 4 25  ? 123.762 105.429 179.729 1.00 106.84 ? 25  ILE G CB  1 
ATOM 6699 C CG1 . ILE D 4 25  ? 124.585 106.649 179.328 1.00 110.84 ? 25  ILE G CG1 1 
ATOM 6700 C CG2 . ILE D 4 25  ? 122.278 105.659 179.482 1.00 107.72 ? 25  ILE G CG2 1 
ATOM 6701 C CD1 . ILE D 4 25  ? 124.581 106.927 177.857 1.00 107.70 ? 25  ILE G CD1 1 
ATOM 6702 N N   . ASP D 4 26  ? 125.802 103.473 180.922 1.00 107.09 ? 26  ASP G N   1 
ATOM 6703 C CA  . ASP D 4 26  ? 127.158 102.950 180.985 1.00 103.62 ? 26  ASP G CA  1 
ATOM 6704 C C   . ASP D 4 26  ? 127.774 102.967 179.595 1.00 99.20  ? 26  ASP G C   1 
ATOM 6705 O O   . ASP D 4 26  ? 127.160 102.493 178.633 1.00 104.38 ? 26  ASP G O   1 
ATOM 6706 C CB  . ASP D 4 26  ? 127.175 101.532 181.552 1.00 110.13 ? 26  ASP G CB  1 
ATOM 6707 C CG  . ASP D 4 26  ? 128.556 100.912 181.519 1.00 110.30 ? 26  ASP G CG  1 
ATOM 6708 O OD1 . ASP D 4 26  ? 129.467 101.457 182.176 1.00 106.61 ? 26  ASP G OD1 1 
ATOM 6709 O OD2 . ASP D 4 26  ? 128.731 99.881  180.836 1.00 113.68 ? 26  ASP G OD2 1 
ATOM 6710 N N   . ARG D 4 27  ? 128.981 103.511 179.492 1.00 92.91  ? 27  ARG G N   1 
ATOM 6711 C CA  . ARG D 4 27  ? 129.702 103.589 178.232 1.00 93.07  ? 27  ARG G CA  1 
ATOM 6712 C C   . ARG D 4 27  ? 131.020 102.842 178.354 1.00 93.77  ? 27  ARG G C   1 
ATOM 6713 O O   . ARG D 4 27  ? 131.671 102.875 179.402 1.00 98.88  ? 27  ARG G O   1 
ATOM 6714 C CB  . ARG D 4 27  ? 129.966 105.041 177.825 1.00 98.24  ? 27  ARG G CB  1 
ATOM 6715 C CG  . ARG D 4 27  ? 128.784 105.974 178.005 1.00 105.10 ? 27  ARG G CG  1 
ATOM 6716 C CD  . ARG D 4 27  ? 129.204 107.430 177.778 1.00 108.15 ? 27  ARG G CD  1 
ATOM 6717 N NE  . ARG D 4 27  ? 128.152 108.429 177.965 1.00 119.17 ? 27  ARG G NE  1 
ATOM 6718 C CZ  . ARG D 4 27  ? 127.467 108.654 179.082 1.00 124.49 ? 27  ARG G CZ  1 
ATOM 6719 N NH1 . ARG D 4 27  ? 127.764 108.050 180.222 1.00 120.69 ? 27  ARG G NH1 1 
ATOM 6720 N NH2 . ARG D 4 27  ? 126.477 109.542 179.064 1.00 128.41 ? 27  ARG G NH2 1 
ATOM 6721 N N   . ILE D 4 28  ? 131.406 102.174 177.277 1.00 89.23  ? 28  ILE G N   1 
ATOM 6722 C CA  . ILE D 4 28  ? 132.643 101.410 177.213 1.00 91.85  ? 28  ILE G CA  1 
ATOM 6723 C C   . ILE D 4 28  ? 133.637 102.224 176.392 1.00 96.28  ? 28  ILE G C   1 
ATOM 6724 O O   . ILE D 4 28  ? 133.244 102.982 175.499 1.00 98.22  ? 28  ILE G O   1 
ATOM 6725 C CB  . ILE D 4 28  ? 132.355 100.005 176.626 1.00 94.26  ? 28  ILE G CB  1 
ATOM 6726 C CG1 . ILE D 4 28  ? 133.614 99.249  176.188 1.00 97.03  ? 28  ILE G CG1 1 
ATOM 6727 C CG2 . ILE D 4 28  ? 131.383 100.108 175.478 1.00 92.08  ? 28  ILE G CG2 1 
ATOM 6728 C CD1 . ILE D 4 28  ? 133.333 97.855  175.665 1.00 91.43  ? 28  ILE G CD1 1 
ATOM 6729 N N   . LYS D 4 29  ? 134.924 102.104 176.742 1.00 96.25  ? 29  LYS G N   1 
ATOM 6730 C CA  . LYS D 4 29  ? 136.003 102.899 176.162 1.00 91.31  ? 29  LYS G CA  1 
ATOM 6731 C C   . LYS D 4 29  ? 136.066 102.762 174.640 1.00 97.84  ? 29  LYS G C   1 
ATOM 6732 O O   . LYS D 4 29  ? 135.582 101.793 174.049 1.00 102.19 ? 29  LYS G O   1 
ATOM 6733 C CB  . LYS D 4 29  ? 137.344 102.486 176.767 1.00 85.85  ? 29  LYS G CB  1 
ATOM 6734 C CG  . LYS D 4 29  ? 138.316 103.632 176.978 1.00 90.36  ? 29  LYS G CG  1 
ATOM 6735 C CD  . LYS D 4 29  ? 138.362 104.066 178.431 1.00 93.76  ? 29  LYS G CD  1 
ATOM 6736 C CE  . LYS D 4 29  ? 138.922 102.966 179.316 1.00 98.02  ? 29  LYS G CE  1 
ATOM 6737 N NZ  . LYS D 4 29  ? 139.092 103.421 180.723 1.00 95.33  ? 29  LYS G NZ  1 
ATOM 6738 N N   . VAL D 4 30  ? 136.684 103.768 174.014 1.00 95.52  ? 30  VAL G N   1 
ATOM 6739 C CA  . VAL D 4 30  ? 136.680 103.895 172.560 1.00 92.14  ? 30  VAL G CA  1 
ATOM 6740 C C   . VAL D 4 30  ? 137.483 102.771 171.914 1.00 92.18  ? 30  VAL G C   1 
ATOM 6741 O O   . VAL D 4 30  ? 137.098 102.243 170.862 1.00 94.87  ? 30  VAL G O   1 
ATOM 6742 C CB  . VAL D 4 30  ? 137.205 105.292 172.169 1.00 89.88  ? 30  VAL G CB  1 
ATOM 6743 C CG1 . VAL D 4 30  ? 137.755 105.330 170.747 1.00 89.31  ? 30  VAL G CG1 1 
ATOM 6744 C CG2 . VAL D 4 30  ? 136.114 106.334 172.343 1.00 90.21  ? 30  VAL G CG2 1 
ATOM 6745 N N   . SER D 4 31  ? 138.585 102.363 172.554 1.00 94.71  ? 31  SER G N   1 
ATOM 6746 C CA  . SER D 4 31  ? 139.509 101.402 171.955 1.00 98.09  ? 31  SER G CA  1 
ATOM 6747 C C   . SER D 4 31  ? 138.859 100.039 171.749 1.00 96.16  ? 31  SER G C   1 
ATOM 6748 O O   . SER D 4 31  ? 139.112 99.374  170.738 1.00 96.91  ? 31  SER G O   1 
ATOM 6749 C CB  . SER D 4 31  ? 140.759 101.269 172.824 1.00 103.20 ? 31  SER G CB  1 
ATOM 6750 O OG  . SER D 4 31  ? 140.524 100.408 173.924 1.00 105.59 ? 31  SER G OG  1 
ATOM 6751 N N   . LYS D 4 32  ? 138.010 99.615  172.688 1.00 94.56  ? 32  LYS G N   1 
ATOM 6752 C CA  . LYS D 4 32  ? 137.289 98.355  172.523 1.00 97.08  ? 32  LYS G CA  1 
ATOM 6753 C C   . LYS D 4 32  ? 136.324 98.414  171.346 1.00 98.86  ? 32  LYS G C   1 
ATOM 6754 O O   . LYS D 4 32  ? 136.213 97.451  170.576 1.00 102.54 ? 32  LYS G O   1 
ATOM 6755 C CB  . LYS D 4 32  ? 136.543 98.006  173.809 1.00 99.17  ? 32  LYS G CB  1 
ATOM 6756 C CG  . LYS D 4 32  ? 137.432 97.480  174.922 1.00 102.96 ? 32  LYS G CG  1 
ATOM 6757 C CD  . LYS D 4 32  ? 138.192 96.245  174.470 1.00 108.42 ? 32  LYS G CD  1 
ATOM 6758 C CE  . LYS D 4 32  ? 137.293 95.018  174.476 1.00 105.48 ? 32  LYS G CE  1 
ATOM 6759 N NZ  . LYS D 4 32  ? 138.013 93.795  174.027 1.00 105.81 ? 32  LYS G NZ  1 
ATOM 6760 N N   . ALA D 4 33  ? 135.630 99.543  171.180 1.00 97.26  ? 33  ALA G N   1 
ATOM 6761 C CA  . ALA D 4 33  ? 134.702 99.689  170.063 1.00 94.09  ? 33  ALA G CA  1 
ATOM 6762 C C   . ALA D 4 33  ? 135.435 99.740  168.730 1.00 89.34  ? 33  ALA G C   1 
ATOM 6763 O O   . ALA D 4 33  ? 134.973 99.161  167.741 1.00 91.33  ? 33  ALA G O   1 
ATOM 6764 C CB  . ALA D 4 33  ? 133.853 100.940 170.248 1.00 87.68  ? 33  ALA G CB  1 
ATOM 6765 N N   . ALA D 4 34  ? 136.579 100.424 168.687 1.00 86.46  ? 34  ALA G N   1 
ATOM 6766 C CA  . ALA D 4 34  ? 137.375 100.466 167.466 1.00 84.87  ? 34  ALA G CA  1 
ATOM 6767 C C   . ALA D 4 34  ? 137.937 99.092  167.125 1.00 85.91  ? 34  ALA G C   1 
ATOM 6768 O O   . ALA D 4 34  ? 137.985 98.711  165.950 1.00 86.43  ? 34  ALA G O   1 
ATOM 6769 C CB  . ALA D 4 34  ? 138.501 101.489 167.608 1.00 85.63  ? 34  ALA G CB  1 
ATOM 6770 N N   . ALA D 4 35  ? 138.362 98.334  168.141 1.00 89.12  ? 35  ALA G N   1 
ATOM 6771 C CA  . ALA D 4 35  ? 138.850 96.980  167.907 1.00 89.70  ? 35  ALA G CA  1 
ATOM 6772 C C   . ALA D 4 35  ? 137.739 96.072  167.401 1.00 90.82  ? 35  ALA G C   1 
ATOM 6773 O O   . ALA D 4 35  ? 137.965 95.258  166.499 1.00 91.45  ? 35  ALA G O   1 
ATOM 6774 C CB  . ALA D 4 35  ? 139.465 96.416  169.187 1.00 89.82  ? 35  ALA G CB  1 
ATOM 6775 N N   . ASP D 4 36  ? 136.532 96.206  167.960 1.00 94.12  ? 36  ASP G N   1 
ATOM 6776 C CA  . ASP D 4 36  ? 135.396 95.421  167.486 1.00 91.21  ? 36  ASP G CA  1 
ATOM 6777 C C   . ASP D 4 36  ? 135.025 95.791  166.055 1.00 86.90  ? 36  ASP G C   1 
ATOM 6778 O O   . ASP D 4 36  ? 134.703 94.915  165.243 1.00 88.58  ? 36  ASP G O   1 
ATOM 6779 C CB  . ASP D 4 36  ? 134.200 95.622  168.416 1.00 95.89  ? 36  ASP G CB  1 
ATOM 6780 C CG  . ASP D 4 36  ? 134.378 94.929  169.754 1.00 104.92 ? 36  ASP G CG  1 
ATOM 6781 O OD1 . ASP D 4 36  ? 135.424 94.279  169.958 1.00 110.51 ? 36  ASP G OD1 1 
ATOM 6782 O OD2 . ASP D 4 36  ? 133.470 95.040  170.604 1.00 107.24 ? 36  ASP G OD2 1 
ATOM 6783 N N   . LEU D 4 37  ? 135.077 97.085  165.732 1.00 83.42  ? 37  LEU G N   1 
ATOM 6784 C CA  . LEU D 4 37  ? 134.759 97.549  164.386 1.00 77.90  ? 37  LEU G CA  1 
ATOM 6785 C C   . LEU D 4 37  ? 135.772 97.023  163.373 1.00 81.00  ? 37  LEU G C   1 
ATOM 6786 O O   . LEU D 4 37  ? 135.402 96.553  162.288 1.00 83.30  ? 37  LEU G O   1 
ATOM 6787 C CB  . LEU D 4 37  ? 134.747 99.077  164.384 1.00 78.27  ? 37  LEU G CB  1 
ATOM 6788 C CG  . LEU D 4 37  ? 133.993 99.867  163.326 1.00 75.40  ? 37  LEU G CG  1 
ATOM 6789 C CD1 . LEU D 4 37  ? 132.668 99.207  163.145 1.00 75.18  ? 37  LEU G CD1 1 
ATOM 6790 C CD2 . LEU D 4 37  ? 133.813 101.308 163.759 1.00 74.81  ? 37  LEU G CD2 1 
ATOM 6791 N N   . MET D 4 38  ? 137.059 97.078  163.730 1.00 81.69  ? 38  MET G N   1 
ATOM 6792 C CA  . MET D 4 38  ? 138.116 96.564  162.866 1.00 80.28  ? 38  MET G CA  1 
ATOM 6793 C C   . MET D 4 38  ? 138.009 95.051  162.707 1.00 84.98  ? 38  MET G C   1 
ATOM 6794 O O   . MET D 4 38  ? 138.235 94.515  161.614 1.00 91.26  ? 38  MET G O   1 
ATOM 6795 C CB  . MET D 4 38  ? 139.476 96.962  163.444 1.00 85.78  ? 38  MET G CB  1 
ATOM 6796 C CG  . MET D 4 38  ? 140.658 96.114  163.005 1.00 97.69  ? 38  MET G CG  1 
ATOM 6797 S SD  . MET D 4 38  ? 142.151 97.100  162.781 1.00 135.55 ? 38  MET G SD  1 
ATOM 6798 C CE  . MET D 4 38  ? 141.645 98.164  161.435 1.00 115.13 ? 38  MET G CE  1 
ATOM 6799 N N   . ALA D 4 39  ? 137.654 94.349  163.788 1.00 84.42  ? 39  ALA G N   1 
ATOM 6800 C CA  . ALA D 4 39  ? 137.479 92.903  163.723 1.00 85.63  ? 39  ALA G CA  1 
ATOM 6801 C C   . ALA D 4 39  ? 136.310 92.526  162.825 1.00 86.57  ? 39  ALA G C   1 
ATOM 6802 O O   . ALA D 4 39  ? 136.384 91.537  162.087 1.00 91.74  ? 39  ALA G O   1 
ATOM 6803 C CB  . ALA D 4 39  ? 137.282 92.332  165.127 1.00 84.44  ? 39  ALA G CB  1 
ATOM 6804 N N   . TYR D 4 40  ? 135.223 93.299  162.874 1.00 85.98  ? 40  TYR G N   1 
ATOM 6805 C CA  . TYR D 4 40  ? 134.104 93.036  161.975 1.00 91.87  ? 40  TYR G CA  1 
ATOM 6806 C C   . TYR D 4 40  ? 134.475 93.326  160.529 1.00 91.12  ? 40  TYR G C   1 
ATOM 6807 O O   . TYR D 4 40  ? 134.010 92.634  159.617 1.00 95.92  ? 40  TYR G O   1 
ATOM 6808 C CB  . TYR D 4 40  ? 132.878 93.853  162.374 1.00 95.54  ? 40  TYR G CB  1 
ATOM 6809 C CG  . TYR D 4 40  ? 131.647 93.455  161.592 1.00 94.18  ? 40  TYR G CG  1 
ATOM 6810 C CD1 . TYR D 4 40  ? 130.919 92.324  161.935 1.00 97.76  ? 40  TYR G CD1 1 
ATOM 6811 C CD2 . TYR D 4 40  ? 131.226 94.196  160.496 1.00 92.79  ? 40  TYR G CD2 1 
ATOM 6812 C CE1 . TYR D 4 40  ? 129.800 91.949  161.217 1.00 99.85  ? 40  TYR G CE1 1 
ATOM 6813 C CE2 . TYR D 4 40  ? 130.112 93.827  159.771 1.00 100.05 ? 40  TYR G CE2 1 
ATOM 6814 C CZ  . TYR D 4 40  ? 129.402 92.704  160.137 1.00 102.71 ? 40  TYR G CZ  1 
ATOM 6815 O OH  . TYR D 4 40  ? 128.288 92.335  159.419 1.00 107.41 ? 40  TYR G OH  1 
ATOM 6816 N N   . CYS D 4 41  ? 135.283 94.363  160.299 1.00 87.46  ? 41  CYS G N   1 
ATOM 6817 C CA  . CYS D 4 41  ? 135.711 94.664  158.937 1.00 86.67  ? 41  CYS G CA  1 
ATOM 6818 C C   . CYS D 4 41  ? 136.610 93.566  158.380 1.00 87.27  ? 41  CYS G C   1 
ATOM 6819 O O   . CYS D 4 41  ? 136.485 93.189  157.210 1.00 91.07  ? 41  CYS G O   1 
ATOM 6820 C CB  . CYS D 4 41  ? 136.422 96.014  158.898 1.00 93.35  ? 41  CYS G CB  1 
ATOM 6821 S SG  . CYS D 4 41  ? 135.343 97.409  158.502 1.00 123.10 ? 41  CYS G SG  1 
ATOM 6822 N N   . GLU D 4 42  ? 137.519 93.037  159.200 1.00 87.17  ? 42  GLU G N   1 
ATOM 6823 C CA  . GLU D 4 42  ? 138.416 91.986  158.731 1.00 86.43  ? 42  GLU G CA  1 
ATOM 6824 C C   . GLU D 4 42  ? 137.736 90.627  158.646 1.00 88.10  ? 42  GLU G C   1 
ATOM 6825 O O   . GLU D 4 42  ? 138.183 89.777  157.869 1.00 89.71  ? 42  GLU G O   1 
ATOM 6826 C CB  . GLU D 4 42  ? 139.679 91.944  159.613 1.00 89.50  ? 42  GLU G CB  1 
ATOM 6827 C CG  . GLU D 4 42  ? 139.579 91.402  161.062 1.00 95.20  ? 42  GLU G CG  1 
ATOM 6828 C CD  . GLU D 4 42  ? 139.459 89.888  161.185 1.00 98.22  ? 42  GLU G CD  1 
ATOM 6829 O OE1 . GLU D 4 42  ? 140.381 89.176  160.732 1.00 100.47 ? 42  GLU G OE1 1 
ATOM 6830 O OE2 . GLU D 4 42  ? 138.442 89.414  161.734 1.00 100.12 ? 42  GLU G OE2 1 
ATOM 6831 N N   . ALA D 4 43  ? 136.680 90.398  159.429 1.00 91.21  ? 43  ALA G N   1 
ATOM 6832 C CA  . ALA D 4 43  ? 136.006 89.105  159.395 1.00 94.81  ? 43  ALA G CA  1 
ATOM 6833 C C   . ALA D 4 43  ? 135.183 88.922  158.126 1.00 93.62  ? 43  ALA G C   1 
ATOM 6834 O O   . ALA D 4 43  ? 135.082 87.802  157.613 1.00 94.11  ? 43  ALA G O   1 
ATOM 6835 C CB  . ALA D 4 43  ? 135.118 88.942  160.628 1.00 93.16  ? 43  ALA G CB  1 
ATOM 6836 N N   . HIS D 4 44  ? 134.591 89.996  157.607 1.00 91.68  ? 44  HIS G N   1 
ATOM 6837 C CA  . HIS D 4 44  ? 133.710 89.923  156.450 1.00 92.45  ? 44  HIS G CA  1 
ATOM 6838 C C   . HIS D 4 44  ? 134.338 90.519  155.197 1.00 93.06  ? 44  HIS G C   1 
ATOM 6839 O O   . HIS D 4 44  ? 133.626 90.817  154.234 1.00 98.80  ? 44  HIS G O   1 
ATOM 6840 C CB  . HIS D 4 44  ? 132.383 90.615  156.755 1.00 94.96  ? 44  HIS G CB  1 
ATOM 6841 C CG  . HIS D 4 44  ? 131.503 89.843  157.685 1.00 101.87 ? 44  HIS G CG  1 
ATOM 6842 N ND1 . HIS D 4 44  ? 130.545 88.958  157.239 1.00 110.34 ? 44  HIS G ND1 1 
ATOM 6843 C CD2 . HIS D 4 44  ? 131.440 89.817  159.036 1.00 104.34 ? 44  HIS G CD2 1 
ATOM 6844 C CE1 . HIS D 4 44  ? 129.927 88.423  158.277 1.00 114.64 ? 44  HIS G CE1 1 
ATOM 6845 N NE2 . HIS D 4 44  ? 130.451 88.928  159.379 1.00 113.48 ? 44  HIS G NE2 1 
ATOM 6846 N N   . ALA D 4 45  ? 135.658 90.697  155.187 1.00 89.84  ? 45  ALA G N   1 
ATOM 6847 C CA  . ALA D 4 45  ? 136.319 91.240  154.008 1.00 93.46  ? 45  ALA G CA  1 
ATOM 6848 C C   . ALA D 4 45  ? 136.387 90.237  152.866 1.00 95.77  ? 45  ALA G C   1 
ATOM 6849 O O   . ALA D 4 45  ? 136.489 90.646  151.705 1.00 97.94  ? 45  ALA G O   1 
ATOM 6850 C CB  . ALA D 4 45  ? 137.728 91.715  154.368 1.00 90.32  ? 45  ALA G CB  1 
ATOM 6851 N N   . LYS D 4 46  ? 136.336 88.940  153.165 1.00 93.47  ? 46  LYS G N   1 
ATOM 6852 C CA  . LYS D 4 46  ? 136.440 87.927  152.121 1.00 94.58  ? 46  LYS G CA  1 
ATOM 6853 C C   . LYS D 4 46  ? 135.145 87.787  151.329 1.00 99.15  ? 46  LYS G C   1 
ATOM 6854 O O   . LYS D 4 46  ? 135.182 87.542  150.118 1.00 100.76 ? 46  LYS G O   1 
ATOM 6855 C CB  . LYS D 4 46  ? 136.838 86.586  152.738 1.00 95.41  ? 46  LYS G CB  1 
ATOM 6856 C CG  . LYS D 4 46  ? 136.460 86.448  154.204 1.00 102.71 ? 46  LYS G CG  1 
ATOM 6857 C CD  . LYS D 4 46  ? 137.128 85.242  154.841 1.00 103.67 ? 46  LYS G CD  1 
ATOM 6858 C CE  . LYS D 4 46  ? 136.729 85.102  156.301 1.00 106.50 ? 46  LYS G CE  1 
ATOM 6859 N NZ  . LYS D 4 46  ? 137.174 86.268  157.113 1.00 102.15 ? 46  LYS G NZ  1 
ATOM 6860 N N   . GLU D 4 47  ? 133.995 87.938  151.985 1.00 99.05  ? 47  GLU G N   1 
ATOM 6861 C CA  . GLU D 4 47  ? 132.696 87.785  151.339 1.00 97.51  ? 47  GLU G CA  1 
ATOM 6862 C C   . GLU D 4 47  ? 132.068 89.123  150.969 1.00 90.34  ? 47  GLU G C   1 
ATOM 6863 O O   . GLU D 4 47  ? 130.841 89.257  150.988 1.00 93.18  ? 47  GLU G O   1 
ATOM 6864 C CB  . GLU D 4 47  ? 131.740 86.984  152.224 1.00 108.81 ? 47  GLU G CB  1 
ATOM 6865 C CG  . GLU D 4 47  ? 131.776 85.466  152.030 1.00 114.58 ? 47  GLU G CG  1 
ATOM 6866 C CD  . GLU D 4 47  ? 133.176 84.896  151.938 1.00 115.35 ? 47  GLU G CD  1 
ATOM 6867 O OE1 . GLU D 4 47  ? 133.881 84.885  152.967 1.00 114.10 ? 47  GLU G OE1 1 
ATOM 6868 O OE2 . GLU D 4 47  ? 133.572 84.459  150.837 1.00 117.71 ? 47  GLU G OE2 1 
ATOM 6869 N N   . ASP D 4 48  ? 132.886 90.116  150.622 1.00 89.89  ? 48  ASP G N   1 
ATOM 6870 C CA  . ASP D 4 48  ? 132.410 91.431  150.203 1.00 90.03  ? 48  ASP G CA  1 
ATOM 6871 C C   . ASP D 4 48  ? 132.746 91.608  148.731 1.00 84.49  ? 48  ASP G C   1 
ATOM 6872 O O   . ASP D 4 48  ? 133.876 91.984  148.389 1.00 90.35  ? 48  ASP G O   1 
ATOM 6873 C CB  . ASP D 4 48  ? 133.048 92.539  151.044 1.00 100.47 ? 48  ASP G CB  1 
ATOM 6874 C CG  . ASP D 4 48  ? 132.500 93.915  150.713 1.00 104.48 ? 48  ASP G CG  1 
ATOM 6875 O OD1 . ASP D 4 48  ? 132.967 94.529  149.730 1.00 105.18 ? 48  ASP G OD1 1 
ATOM 6876 O OD2 . ASP D 4 48  ? 131.603 94.388  151.440 1.00 102.96 ? 48  ASP G OD2 1 
ATOM 6877 N N   . PRO D 4 49  ? 131.803 91.349  147.822 1.00 79.74  ? 49  PRO G N   1 
ATOM 6878 C CA  . PRO D 4 49  ? 132.119 91.423  146.386 1.00 80.83  ? 49  PRO G CA  1 
ATOM 6879 C C   . PRO D 4 49  ? 132.396 92.826  145.884 1.00 79.93  ? 49  PRO G C   1 
ATOM 6880 O O   . PRO D 4 49  ? 132.973 92.972  144.801 1.00 85.69  ? 49  PRO G O   1 
ATOM 6881 C CB  . PRO D 4 49  ? 130.870 90.831  145.722 1.00 85.66  ? 49  PRO G CB  1 
ATOM 6882 C CG  . PRO D 4 49  ? 129.790 90.977  146.735 1.00 90.50  ? 49  PRO G CG  1 
ATOM 6883 C CD  . PRO D 4 49  ? 130.439 90.859  148.071 1.00 88.72  ? 49  PRO G CD  1 
ATOM 6884 N N   . LEU D 4 50  ? 131.999 93.857  146.627 1.00 76.13  ? 50  LEU G N   1 
ATOM 6885 C CA  . LEU D 4 50  ? 132.285 95.231  146.235 1.00 72.51  ? 50  LEU G CA  1 
ATOM 6886 C C   . LEU D 4 50  ? 133.774 95.540  146.297 1.00 79.17  ? 50  LEU G C   1 
ATOM 6887 O O   . LEU D 4 50  ? 134.303 96.244  145.431 1.00 79.35  ? 50  LEU G O   1 
ATOM 6888 C CB  . LEU D 4 50  ? 131.523 96.192  147.142 1.00 77.82  ? 50  LEU G CB  1 
ATOM 6889 C CG  . LEU D 4 50  ? 131.186 97.581  146.614 1.00 72.22  ? 50  LEU G CG  1 
ATOM 6890 C CD1 . LEU D 4 50  ? 130.809 97.529  145.145 1.00 63.51  ? 50  LEU G CD1 1 
ATOM 6891 C CD2 . LEU D 4 50  ? 130.079 98.185  147.458 1.00 72.87  ? 50  LEU G CD2 1 
ATOM 6892 N N   . LEU D 4 51  ? 134.459 95.026  147.317 1.00 84.69  ? 51  LEU G N   1 
ATOM 6893 C CA  . LEU D 4 51  ? 135.856 95.360  147.559 1.00 81.38  ? 51  LEU G CA  1 
ATOM 6894 C C   . LEU D 4 51  ? 136.785 94.570  146.650 1.00 88.35  ? 51  LEU G C   1 
ATOM 6895 O O   . LEU D 4 51  ? 137.495 95.151  145.823 1.00 95.04  ? 51  LEU G O   1 
ATOM 6896 C CB  . LEU D 4 51  ? 136.201 95.102  149.025 1.00 77.93  ? 51  LEU G CB  1 
ATOM 6897 C CG  . LEU D 4 51  ? 137.525 95.642  149.555 1.00 86.14  ? 51  LEU G CG  1 
ATOM 6898 C CD1 . LEU D 4 51  ? 137.304 96.319  150.890 1.00 84.82  ? 51  LEU G CD1 1 
ATOM 6899 C CD2 . LEU D 4 51  ? 138.553 94.528  149.692 1.00 91.42  ? 51  LEU G CD2 1 
ATOM 6900 N N   . THR D 4 52  ? 136.789 93.249  146.797 1.00 92.75  ? 52  THR G N   1 
ATOM 6901 C CA  . THR D 4 52  ? 137.642 92.411  145.973 1.00 102.33 ? 52  THR G CA  1 
ATOM 6902 C C   . THR D 4 52  ? 137.076 92.320  144.556 1.00 102.91 ? 52  THR G C   1 
ATOM 6903 O O   . THR D 4 52  ? 135.864 92.439  144.357 1.00 103.75 ? 52  THR G O   1 
ATOM 6904 C CB  . THR D 4 52  ? 137.773 91.014  146.583 1.00 106.96 ? 52  THR G CB  1 
ATOM 6905 O OG1 . THR D 4 52  ? 138.442 90.139  145.666 1.00 105.31 ? 52  THR G OG1 1 
ATOM 6906 C CG2 . THR D 4 52  ? 136.408 90.437  146.917 1.00 102.41 ? 52  THR G CG2 1 
ATOM 6907 N N   . PRO D 4 53  ? 137.939 92.168  143.549 1.00 104.27 ? 53  PRO G N   1 
ATOM 6908 C CA  . PRO D 4 53  ? 137.444 91.919  142.190 1.00 108.26 ? 53  PRO G CA  1 
ATOM 6909 C C   . PRO D 4 53  ? 136.673 90.609  142.108 1.00 110.61 ? 53  PRO G C   1 
ATOM 6910 O O   . PRO D 4 53  ? 136.991 89.626  142.778 1.00 113.92 ? 53  PRO G O   1 
ATOM 6911 C CB  . PRO D 4 53  ? 138.724 91.869  141.350 1.00 110.11 ? 53  PRO G CB  1 
ATOM 6912 C CG  . PRO D 4 53  ? 139.700 92.692  142.115 1.00 111.80 ? 53  PRO G CG  1 
ATOM 6913 C CD  . PRO D 4 53  ? 139.384 92.456  143.563 1.00 106.10 ? 53  PRO G CD  1 
ATOM 6914 N N   . VAL D 4 54  ? 135.640 90.614  141.268 1.00 108.90 ? 54  VAL G N   1 
ATOM 6915 C CA  . VAL D 4 54  ? 134.711 89.502  141.141 1.00 106.67 ? 54  VAL G CA  1 
ATOM 6916 C C   . VAL D 4 54  ? 134.901 88.904  139.744 1.00 113.61 ? 54  VAL G C   1 
ATOM 6917 O O   . VAL D 4 54  ? 134.953 89.651  138.773 1.00 117.64 ? 54  VAL G O   1 
ATOM 6918 C CB  . VAL D 4 54  ? 133.249 89.940  141.341 1.00 100.81 ? 54  VAL G CB  1 
ATOM 6919 C CG1 . VAL D 4 54  ? 132.269 88.858  140.909 1.00 101.36 ? 54  VAL G CG1 1 
ATOM 6920 C CG2 . VAL D 4 54  ? 133.020 90.312  142.787 1.00 94.58  ? 54  VAL G CG2 1 
ATOM 6921 N N   . PRO D 4 55  ? 135.054 87.583  139.623 1.00 112.86 ? 55  PRO G N   1 
ATOM 6922 C CA  . PRO D 4 55  ? 135.115 86.972  138.288 1.00 110.88 ? 55  PRO G CA  1 
ATOM 6923 C C   . PRO D 4 55  ? 133.810 87.167  137.531 1.00 111.92 ? 55  PRO G C   1 
ATOM 6924 O O   . PRO D 4 55  ? 132.723 87.135  138.110 1.00 113.10 ? 55  PRO G O   1 
ATOM 6925 C CB  . PRO D 4 55  ? 135.375 85.492  138.591 1.00 107.31 ? 55  PRO G CB  1 
ATOM 6926 C CG  . PRO D 4 55  ? 134.871 85.299  139.983 1.00 105.87 ? 55  PRO G CG  1 
ATOM 6927 C CD  . PRO D 4 55  ? 135.167 86.581  140.694 1.00 108.57 ? 55  PRO G CD  1 
ATOM 6928 N N   . ALA D 4 56  ? 133.931 87.365  136.216 1.00 112.59 ? 56  ALA G N   1 
ATOM 6929 C CA  . ALA D 4 56  ? 132.773 87.704  135.397 1.00 114.19 ? 56  ALA G CA  1 
ATOM 6930 C C   . ALA D 4 56  ? 131.804 86.541  135.229 1.00 111.74 ? 56  ALA G C   1 
ATOM 6931 O O   . ALA D 4 56  ? 130.660 86.764  134.821 1.00 110.35 ? 56  ALA G O   1 
ATOM 6932 C CB  . ALA D 4 56  ? 133.229 88.200  134.025 1.00 116.56 ? 56  ALA G CB  1 
ATOM 6933 N N   . SER D 4 57  ? 132.233 85.312  135.521 1.00 111.18 ? 57  SER G N   1 
ATOM 6934 C CA  . SER D 4 57  ? 131.328 84.171  135.422 1.00 113.37 ? 57  SER G CA  1 
ATOM 6935 C C   . SER D 4 57  ? 130.283 84.203  136.530 1.00 111.65 ? 57  SER G C   1 
ATOM 6936 O O   . SER D 4 57  ? 129.093 83.979  136.283 1.00 114.09 ? 57  SER G O   1 
ATOM 6937 C CB  . SER D 4 57  ? 132.123 82.867  135.467 1.00 116.07 ? 57  SER G CB  1 
ATOM 6938 O OG  . SER D 4 57  ? 132.809 82.732  136.700 1.00 115.54 ? 57  SER G OG  1 
ATOM 6939 N N   . GLU D 4 58  ? 130.710 84.479  137.760 1.00 105.93 ? 58  GLU G N   1 
ATOM 6940 C CA  . GLU D 4 58  ? 129.800 84.560  138.892 1.00 102.54 ? 58  GLU G CA  1 
ATOM 6941 C C   . GLU D 4 58  ? 129.196 85.944  139.071 1.00 99.46  ? 58  GLU G C   1 
ATOM 6942 O O   . GLU D 4 58  ? 128.314 86.112  139.919 1.00 102.87 ? 58  GLU G O   1 
ATOM 6943 C CB  . GLU D 4 58  ? 130.522 84.150  140.181 1.00 100.07 ? 58  GLU G CB  1 
ATOM 6944 N N   . ASN D 4 59  ? 129.646 86.929  138.305 1.00 98.15  ? 59  ASN G N   1 
ATOM 6945 C CA  . ASN D 4 59  ? 129.112 88.280  138.409 1.00 93.87  ? 59  ASN G CA  1 
ATOM 6946 C C   . ASN D 4 59  ? 127.753 88.348  137.725 1.00 93.63  ? 59  ASN G C   1 
ATOM 6947 O O   . ASN D 4 59  ? 127.664 88.066  136.525 1.00 99.34  ? 59  ASN G O   1 
ATOM 6948 C CB  . ASN D 4 59  ? 130.070 89.274  137.767 1.00 98.16  ? 59  ASN G CB  1 
ATOM 6949 C CG  . ASN D 4 59  ? 129.643 90.713  137.964 1.00 98.02  ? 59  ASN G CG  1 
ATOM 6950 O OD1 . ASN D 4 59  ? 128.854 91.027  138.852 1.00 94.07  ? 59  ASN G OD1 1 
ATOM 6951 N ND2 . ASN D 4 59  ? 130.165 91.601  137.127 1.00 103.48 ? 59  ASN G ND2 1 
ATOM 6952 N N   . PRO D 4 60  ? 126.681 88.710  138.434 1.00 88.63  ? 60  PRO G N   1 
ATOM 6953 C CA  . PRO D 4 60  ? 125.376 88.830  137.770 1.00 85.23  ? 60  PRO G CA  1 
ATOM 6954 C C   . PRO D 4 60  ? 125.265 90.040  136.871 1.00 82.81  ? 60  PRO G C   1 
ATOM 6955 O O   . PRO D 4 60  ? 124.358 90.086  136.032 1.00 86.40  ? 60  PRO G O   1 
ATOM 6956 C CB  . PRO D 4 60  ? 124.394 88.920  138.942 1.00 85.38  ? 60  PRO G CB  1 
ATOM 6957 C CG  . PRO D 4 60  ? 125.194 89.498  140.046 1.00 86.01  ? 60  PRO G CG  1 
ATOM 6958 C CD  . PRO D 4 60  ? 126.586 88.956  139.883 1.00 90.73  ? 60  PRO G CD  1 
ATOM 6959 N N   . PHE D 4 61  ? 126.146 91.016  137.011 1.00 84.72  ? 61  PHE G N   1 
ATOM 6960 C CA  . PHE D 4 61  ? 126.105 92.235  136.214 1.00 88.33  ? 61  PHE G CA  1 
ATOM 6961 C C   . PHE D 4 61  ? 127.246 92.178  135.205 1.00 101.58 ? 61  PHE G C   1 
ATOM 6962 O O   . PHE D 4 61  ? 128.407 92.415  135.551 1.00 110.26 ? 61  PHE G O   1 
ATOM 6963 C CB  . PHE D 4 61  ? 126.195 93.474  137.100 1.00 87.48  ? 61  PHE G CB  1 
ATOM 6964 C CG  . PHE D 4 61  ? 124.987 93.687  137.968 1.00 79.16  ? 61  PHE G CG  1 
ATOM 6965 C CD1 . PHE D 4 61  ? 124.861 93.025  139.177 1.00 80.62  ? 61  PHE G CD1 1 
ATOM 6966 C CD2 . PHE D 4 61  ? 123.980 94.549  137.575 1.00 71.40  ? 61  PHE G CD2 1 
ATOM 6967 C CE1 . PHE D 4 61  ? 123.757 93.215  139.972 1.00 75.70  ? 61  PHE G CE1 1 
ATOM 6968 C CE2 . PHE D 4 61  ? 122.873 94.743  138.369 1.00 71.95  ? 61  PHE G CE2 1 
ATOM 6969 C CZ  . PHE D 4 61  ? 122.763 94.077  139.569 1.00 73.18  ? 61  PHE G CZ  1 
ATOM 6970 N N   . ARG D 4 62  ? 126.909 91.867  133.959 1.00 99.43  ? 62  ARG G N   1 
ATOM 6971 C CA  . ARG D 4 62  ? 127.905 91.746  132.904 1.00 100.81 ? 62  ARG G CA  1 
ATOM 6972 C C   . ARG D 4 62  ? 127.299 92.087  131.549 1.00 105.24 ? 62  ARG G C   1 
ATOM 6973 O O   . ARG D 4 62  ? 127.998 92.123  130.538 1.00 106.86 ? 62  ARG G O   1 
ATOM 6974 C CB  . ARG D 4 62  ? 128.491 90.335  132.881 1.00 97.75  ? 62  ARG G CB  1 
ATOM 6975 C CG  . ARG D 4 62  ? 127.553 89.294  132.298 1.00 103.06 ? 62  ARG G CG  1 
ATOM 6976 C CD  . ARG D 4 62  ? 128.174 87.909  132.324 1.00 111.18 ? 62  ARG G CD  1 
ATOM 6977 N NE  . ARG D 4 62  ? 127.162 86.859  132.304 1.00 118.47 ? 62  ARG G NE  1 
ATOM 6978 C CZ  . ARG D 4 62  ? 126.542 86.393  133.379 1.00 114.41 ? 62  ARG G CZ  1 
ATOM 6979 N NH1 . ARG D 4 62  ? 126.811 86.858  134.588 1.00 111.29 ? 62  ARG G NH1 1 
ATOM 6980 N NH2 . ARG D 4 62  ? 125.631 85.435  133.239 1.00 108.33 ? 62  ARG G NH2 1 
ATOM 6981 N N   . GLN E 5 1   ? 129.444 120.004 170.025 1.00 71.11  ? 1   GLN N N   1 
ATOM 6982 C CA  . GLN E 5 1   ? 128.135 120.640 170.113 1.00 80.95  ? 1   GLN N CA  1 
ATOM 6983 C C   . GLN E 5 1   ? 128.178 122.066 169.581 1.00 88.47  ? 1   GLN N C   1 
ATOM 6984 O O   . GLN E 5 1   ? 129.196 122.747 169.691 1.00 93.07  ? 1   GLN N O   1 
ATOM 6985 C CB  . GLN E 5 1   ? 127.635 120.636 171.557 1.00 84.60  ? 1   GLN N CB  1 
ATOM 6986 C CG  . GLN E 5 1   ? 126.125 120.603 171.687 1.00 87.27  ? 1   GLN N CG  1 
ATOM 6987 C CD  . GLN E 5 1   ? 125.527 121.987 171.810 1.00 91.43  ? 1   GLN N CD  1 
ATOM 6988 O OE1 . GLN E 5 1   ? 126.200 122.931 172.221 1.00 90.31  ? 1   GLN N OE1 1 
ATOM 6989 N NE2 . GLN E 5 1   ? 124.254 122.117 171.453 1.00 95.97  ? 1   GLN N NE2 1 
ATOM 6990 N N   . VAL E 5 2   ? 127.066 122.514 169.007 1.00 88.10  ? 2   VAL N N   1 
ATOM 6991 C CA  . VAL E 5 2   ? 126.954 123.845 168.423 1.00 86.92  ? 2   VAL N CA  1 
ATOM 6992 C C   . VAL E 5 2   ? 126.125 124.702 169.367 1.00 90.57  ? 2   VAL N C   1 
ATOM 6993 O O   . VAL E 5 2   ? 124.974 124.367 169.674 1.00 91.06  ? 2   VAL N O   1 
ATOM 6994 C CB  . VAL E 5 2   ? 126.326 123.797 167.022 1.00 84.71  ? 2   VAL N CB  1 
ATOM 6995 C CG1 . VAL E 5 2   ? 125.882 125.183 166.586 1.00 83.77  ? 2   VAL N CG1 1 
ATOM 6996 C CG2 . VAL E 5 2   ? 127.310 123.211 166.022 1.00 84.61  ? 2   VAL N CG2 1 
ATOM 6997 N N   . GLN E 5 3   ? 126.711 125.803 169.832 1.00 90.42  ? 3   GLN N N   1 
ATOM 6998 C CA  . GLN E 5 3   ? 126.020 126.703 170.742 1.00 89.80  ? 3   GLN N CA  1 
ATOM 6999 C C   . GLN E 5 3   ? 126.474 128.128 170.473 1.00 88.54  ? 3   GLN N C   1 
ATOM 7000 O O   . GLN E 5 3   ? 127.555 128.367 169.929 1.00 90.12  ? 3   GLN N O   1 
ATOM 7001 C CB  . GLN E 5 3   ? 126.267 126.324 172.206 1.00 88.82  ? 3   GLN N CB  1 
ATOM 7002 C CG  . GLN E 5 3   ? 127.689 126.546 172.675 1.00 91.66  ? 3   GLN N CG  1 
ATOM 7003 C CD  . GLN E 5 3   ? 127.810 127.722 173.623 1.00 100.64 ? 3   GLN N CD  1 
ATOM 7004 O OE1 . GLN E 5 3   ? 126.956 128.608 173.642 1.00 102.26 ? 3   GLN N OE1 1 
ATOM 7005 N NE2 . GLN E 5 3   ? 128.875 127.736 174.415 1.00 102.51 ? 3   GLN N NE2 1 
ATOM 7006 N N   . LEU E 5 4   ? 125.624 129.076 170.859 1.00 89.95  ? 4   LEU N N   1 
ATOM 7007 C CA  . LEU E 5 4   ? 125.897 130.503 170.689 1.00 91.19  ? 4   LEU N CA  1 
ATOM 7008 C C   . LEU E 5 4   ? 125.493 131.194 171.986 1.00 96.58  ? 4   LEU N C   1 
ATOM 7009 O O   . LEU E 5 4   ? 124.301 131.318 172.283 1.00 98.61  ? 4   LEU N O   1 
ATOM 7010 C CB  . LEU E 5 4   ? 125.143 131.079 169.496 1.00 88.79  ? 4   LEU N CB  1 
ATOM 7011 C CG  . LEU E 5 4   ? 125.555 130.624 168.096 1.00 88.11  ? 4   LEU N CG  1 
ATOM 7012 C CD1 . LEU E 5 4   ? 124.333 130.224 167.291 1.00 84.36  ? 4   LEU N CD1 1 
ATOM 7013 C CD2 . LEU E 5 4   ? 126.326 131.721 167.386 1.00 88.83  ? 4   LEU N CD2 1 
ATOM 7014 N N   . GLN E 5 5   ? 126.482 131.631 172.758 1.00 98.58  ? 5   GLN N N   1 
ATOM 7015 C CA  . GLN E 5 5   ? 126.248 132.322 174.018 1.00 99.81  ? 5   GLN N CA  1 
ATOM 7016 C C   . GLN E 5 5   ? 126.628 133.788 173.852 1.00 100.88 ? 5   GLN N C   1 
ATOM 7017 O O   . GLN E 5 5   ? 127.776 134.102 173.524 1.00 100.43 ? 5   GLN N O   1 
ATOM 7018 C CB  . GLN E 5 5   ? 127.048 131.678 175.149 1.00 96.90  ? 5   GLN N CB  1 
ATOM 7019 C CG  . GLN E 5 5   ? 126.601 132.092 176.540 1.00 99.46  ? 5   GLN N CG  1 
ATOM 7020 C CD  . GLN E 5 5   ? 127.462 133.195 177.123 1.00 105.70 ? 5   GLN N CD  1 
ATOM 7021 O OE1 . GLN E 5 5   ? 128.533 133.504 176.601 1.00 106.04 ? 5   GLN N OE1 1 
ATOM 7022 N NE2 . GLN E 5 5   ? 126.996 133.796 178.211 1.00 109.27 ? 5   GLN N NE2 1 
ATOM 7023 N N   . GLU E 5 6   ? 125.669 134.677 174.088 1.00 101.51 ? 6   GLU N N   1 
ATOM 7024 C CA  . GLU E 5 6   ? 125.855 136.105 173.892 1.00 99.94  ? 6   GLU N CA  1 
ATOM 7025 C C   . GLU E 5 6   ? 125.769 136.833 175.227 1.00 101.54 ? 6   GLU N C   1 
ATOM 7026 O O   . GLU E 5 6   ? 125.180 136.342 176.193 1.00 100.83 ? 6   GLU N O   1 
ATOM 7027 C CB  . GLU E 5 6   ? 124.831 136.697 172.898 1.00 98.24  ? 6   GLU N CB  1 
ATOM 7028 C CG  . GLU E 5 6   ? 123.361 136.265 173.038 1.00 99.14  ? 6   GLU N CG  1 
ATOM 7029 C CD  . GLU E 5 6   ? 123.059 134.872 172.497 1.00 100.74 ? 6   GLU N CD  1 
ATOM 7030 O OE1 . GLU E 5 6   ? 123.990 134.202 172.003 1.00 100.16 ? 6   GLU N OE1 1 
ATOM 7031 O OE2 . GLU E 5 6   ? 121.888 134.447 172.572 1.00 100.47 ? 6   GLU N OE2 1 
ATOM 7032 N N   . SER E 5 7   ? 126.378 138.019 175.268 1.00 101.99 ? 7   SER N N   1 
ATOM 7033 C CA  . SER E 5 7   ? 126.466 138.792 176.501 1.00 101.48 ? 7   SER N CA  1 
ATOM 7034 C C   . SER E 5 7   ? 125.917 140.200 176.315 1.00 96.54  ? 7   SER N C   1 
ATOM 7035 O O   . SER E 5 7   ? 125.348 140.520 175.268 1.00 96.17  ? 7   SER N O   1 
ATOM 7036 C CB  . SER E 5 7   ? 127.915 138.854 176.988 1.00 102.27 ? 7   SER N CB  1 
ATOM 7037 O OG  . SER E 5 7   ? 128.753 139.449 176.013 1.00 101.30 ? 7   SER N OG  1 
ATOM 7038 N N   . GLY E 5 8   ? 126.085 141.045 177.326 1.00 95.07  ? 8   GLY N N   1 
ATOM 7039 C CA  . GLY E 5 8   ? 125.566 142.394 177.277 1.00 95.54  ? 8   GLY N CA  1 
ATOM 7040 C C   . GLY E 5 8   ? 124.093 142.450 177.626 1.00 95.74  ? 8   GLY N C   1 
ATOM 7041 O O   . GLY E 5 8   ? 123.455 141.454 177.965 1.00 95.18  ? 8   GLY N O   1 
ATOM 7042 N N   . GLY E 5 9   ? 123.545 143.658 177.541 1.00 93.94  ? 9   GLY N N   1 
ATOM 7043 C CA  . GLY E 5 9   ? 122.134 143.853 177.804 1.00 93.73  ? 9   GLY N CA  1 
ATOM 7044 C C   . GLY E 5 9   ? 121.833 144.445 179.164 1.00 94.56  ? 9   GLY N C   1 
ATOM 7045 O O   . GLY E 5 9   ? 122.345 143.975 180.184 1.00 95.40  ? 9   GLY N O   1 
ATOM 7046 N N   . GLY E 5 10  ? 120.999 145.477 179.189 1.00 92.55  ? 10  GLY N N   1 
ATOM 7047 C CA  . GLY E 5 10  ? 120.639 146.116 180.440 1.00 94.15  ? 10  GLY N CA  1 
ATOM 7048 C C   . GLY E 5 10  ? 119.745 147.305 180.177 1.00 97.37  ? 10  GLY N C   1 
ATOM 7049 O O   . GLY E 5 10  ? 119.466 147.664 179.028 1.00 97.08  ? 10  GLY N O   1 
ATOM 7050 N N   . LEU E 5 11  ? 119.297 147.921 181.268 1.00 99.33  ? 11  LEU N N   1 
ATOM 7051 C CA  . LEU E 5 11  ? 118.425 149.087 181.199 1.00 101.11 ? 11  LEU N CA  1 
ATOM 7052 C C   . LEU E 5 11  ? 119.287 150.324 180.980 1.00 102.81 ? 11  LEU N C   1 
ATOM 7053 O O   . LEU E 5 11  ? 120.026 150.743 181.877 1.00 104.30 ? 11  LEU N O   1 
ATOM 7054 C CB  . LEU E 5 11  ? 117.586 149.213 182.468 1.00 102.24 ? 11  LEU N CB  1 
ATOM 7055 C CG  . LEU E 5 11  ? 116.801 150.516 182.649 1.00 104.63 ? 11  LEU N CG  1 
ATOM 7056 C CD1 . LEU E 5 11  ? 115.756 150.681 181.555 1.00 104.70 ? 11  LEU N CD1 1 
ATOM 7057 C CD2 . LEU E 5 11  ? 116.154 150.566 184.025 1.00 103.97 ? 11  LEU N CD2 1 
ATOM 7058 N N   . VAL E 5 12  ? 119.204 150.901 179.782 1.00 101.72 ? 12  VAL N N   1 
ATOM 7059 C CA  . VAL E 5 12  ? 119.951 152.102 179.438 1.00 100.78 ? 12  VAL N CA  1 
ATOM 7060 C C   . VAL E 5 12  ? 118.971 153.204 179.056 1.00 105.49 ? 12  VAL N C   1 
ATOM 7061 O O   . VAL E 5 12  ? 117.792 152.963 178.783 1.00 106.53 ? 12  VAL N O   1 
ATOM 7062 C CB  . VAL E 5 12  ? 120.971 151.863 178.302 1.00 98.79  ? 12  VAL N CB  1 
ATOM 7063 C CG1 . VAL E 5 12  ? 121.733 150.565 178.520 1.00 97.23  ? 12  VAL N CG1 1 
ATOM 7064 C CG2 . VAL E 5 12  ? 120.278 151.851 176.950 1.00 103.81 ? 12  VAL N CG2 1 
ATOM 7065 N N   . GLN E 5 13  ? 119.475 154.431 179.067 1.00 107.61 ? 13  GLN N N   1 
ATOM 7066 C CA  . GLN E 5 13  ? 118.707 155.592 178.661 1.00 110.05 ? 13  GLN N CA  1 
ATOM 7067 C C   . GLN E 5 13  ? 118.625 155.666 177.139 1.00 109.65 ? 13  GLN N C   1 
ATOM 7068 O O   . GLN E 5 13  ? 119.454 155.079 176.439 1.00 109.61 ? 13  GLN N O   1 
ATOM 7069 C CB  . GLN E 5 13  ? 119.347 156.855 179.228 1.00 110.74 ? 13  GLN N CB  1 
ATOM 7070 C CG  . GLN E 5 13  ? 119.400 156.882 180.746 1.00 112.17 ? 13  GLN N CG  1 
ATOM 7071 C CD  . GLN E 5 13  ? 118.022 156.871 181.379 1.00 114.61 ? 13  GLN N CD  1 
ATOM 7072 O OE1 . GLN E 5 13  ? 117.084 157.483 180.867 1.00 117.66 ? 13  GLN N OE1 1 
ATOM 7073 N NE2 . GLN E 5 13  ? 117.892 156.170 182.498 1.00 111.93 ? 13  GLN N NE2 1 
ATOM 7074 N N   . PRO E 5 14  ? 117.609 156.347 176.600 1.00 108.95 ? 14  PRO N N   1 
ATOM 7075 C CA  . PRO E 5 14  ? 117.547 156.543 175.145 1.00 107.02 ? 14  PRO N CA  1 
ATOM 7076 C C   . PRO E 5 14  ? 118.728 157.354 174.632 1.00 105.59 ? 14  PRO N C   1 
ATOM 7077 O O   . PRO E 5 14  ? 119.233 158.252 175.308 1.00 106.78 ? 14  PRO N O   1 
ATOM 7078 C CB  . PRO E 5 14  ? 116.225 157.290 174.945 1.00 105.60 ? 14  PRO N CB  1 
ATOM 7079 C CG  . PRO E 5 14  ? 115.396 156.893 176.105 1.00 109.02 ? 14  PRO N CG  1 
ATOM 7080 C CD  . PRO E 5 14  ? 116.348 156.741 177.254 1.00 110.89 ? 14  PRO N CD  1 
ATOM 7081 N N   . GLY E 5 15  ? 119.171 157.018 173.423 1.00 105.77 ? 15  GLY N N   1 
ATOM 7082 C CA  . GLY E 5 15  ? 120.310 157.679 172.825 1.00 109.99 ? 15  GLY N CA  1 
ATOM 7083 C C   . GLY E 5 15  ? 121.653 157.276 173.386 1.00 114.32 ? 15  GLY N C   1 
ATOM 7084 O O   . GLY E 5 15  ? 122.654 157.938 173.089 1.00 117.30 ? 15  GLY N O   1 
ATOM 7085 N N   . GLY E 5 16  ? 121.711 156.213 174.186 1.00 113.72 ? 16  GLY N N   1 
ATOM 7086 C CA  . GLY E 5 16  ? 122.939 155.793 174.825 1.00 115.85 ? 16  GLY N CA  1 
ATOM 7087 C C   . GLY E 5 16  ? 123.769 154.874 173.949 1.00 115.88 ? 16  GLY N C   1 
ATOM 7088 O O   . GLY E 5 16  ? 123.508 154.685 172.760 1.00 113.09 ? 16  GLY N O   1 
ATOM 7089 N N   . SER E 5 17  ? 124.797 154.298 174.566 1.00 116.31 ? 17  SER N N   1 
ATOM 7090 C CA  . SER E 5 17  ? 125.707 153.376 173.903 1.00 114.23 ? 17  SER N CA  1 
ATOM 7091 C C   . SER E 5 17  ? 125.711 152.045 174.641 1.00 112.15 ? 17  SER N C   1 
ATOM 7092 O O   . SER E 5 17  ? 125.740 152.009 175.875 1.00 113.33 ? 17  SER N O   1 
ATOM 7093 C CB  . SER E 5 17  ? 127.128 153.946 173.842 1.00 112.76 ? 17  SER N CB  1 
ATOM 7094 O OG  . SER E 5 17  ? 127.175 155.112 173.038 1.00 113.20 ? 17  SER N OG  1 
ATOM 7095 N N   . LEU E 5 18  ? 125.681 150.953 173.880 1.00 107.30 ? 18  LEU N N   1 
ATOM 7096 C CA  . LEU E 5 18  ? 125.662 149.618 174.462 1.00 100.65 ? 18  LEU N CA  1 
ATOM 7097 C C   . LEU E 5 18  ? 126.286 148.653 173.466 1.00 99.10  ? 18  LEU N C   1 
ATOM 7098 O O   . LEU E 5 18  ? 125.864 148.596 172.309 1.00 99.42  ? 18  LEU N O   1 
ATOM 7099 C CB  . LEU E 5 18  ? 124.230 149.201 174.815 1.00 99.48  ? 18  LEU N CB  1 
ATOM 7100 C CG  . LEU E 5 18  ? 123.784 147.735 174.824 1.00 104.83 ? 18  LEU N CG  1 
ATOM 7101 C CD1 . LEU E 5 18  ? 124.532 146.903 175.868 1.00 102.93 ? 18  LEU N CD1 1 
ATOM 7102 C CD2 . LEU E 5 18  ? 122.285 147.660 175.052 1.00 103.13 ? 18  LEU N CD2 1 
ATOM 7103 N N   . ARG E 5 19  ? 127.286 147.902 173.918 1.00 97.92  ? 19  ARG N N   1 
ATOM 7104 C CA  . ARG E 5 19  ? 128.007 146.953 173.078 1.00 96.11  ? 19  ARG N CA  1 
ATOM 7105 C C   . ARG E 5 19  ? 127.416 145.569 173.309 1.00 98.00  ? 19  ARG N C   1 
ATOM 7106 O O   . ARG E 5 19  ? 127.687 144.936 174.334 1.00 101.83 ? 19  ARG N O   1 
ATOM 7107 C CB  . ARG E 5 19  ? 129.499 146.968 173.399 1.00 100.16 ? 19  ARG N CB  1 
ATOM 7108 C CG  . ARG E 5 19  ? 130.361 147.729 172.407 1.00 100.98 ? 19  ARG N CG  1 
ATOM 7109 C CD  . ARG E 5 19  ? 130.478 146.984 171.093 1.00 99.08  ? 19  ARG N CD  1 
ATOM 7110 N NE  . ARG E 5 19  ? 131.232 145.742 171.229 1.00 102.88 ? 19  ARG N NE  1 
ATOM 7111 C CZ  . ARG E 5 19  ? 132.555 145.657 171.211 1.00 103.75 ? 19  ARG N CZ  1 
ATOM 7112 N NH1 . ARG E 5 19  ? 133.315 146.729 171.055 1.00 105.82 ? 19  ARG N NH1 1 
ATOM 7113 N NH2 . ARG E 5 19  ? 133.130 144.466 171.352 1.00 98.44  ? 19  ARG N NH2 1 
ATOM 7114 N N   . LEU E 5 20  ? 126.616 145.100 172.358 1.00 96.94  ? 20  LEU N N   1 
ATOM 7115 C CA  . LEU E 5 20  ? 125.938 143.811 172.468 1.00 95.77  ? 20  LEU N CA  1 
ATOM 7116 C C   . LEU E 5 20  ? 126.881 142.762 171.886 1.00 97.26  ? 20  LEU N C   1 
ATOM 7117 O O   . LEU E 5 20  ? 126.965 142.596 170.668 1.00 97.67  ? 20  LEU N O   1 
ATOM 7118 C CB  . LEU E 5 20  ? 124.595 143.848 171.745 1.00 89.49  ? 20  LEU N CB  1 
ATOM 7119 C CG  . LEU E 5 20  ? 123.458 142.939 172.228 1.00 91.23  ? 20  LEU N CG  1 
ATOM 7120 C CD1 . LEU E 5 20  ? 122.131 143.436 171.673 1.00 90.96  ? 20  LEU N CD1 1 
ATOM 7121 C CD2 . LEU E 5 20  ? 123.664 141.473 171.873 1.00 92.41  ? 20  LEU N CD2 1 
ATOM 7122 N N   . SER E 5 21  ? 127.583 142.049 172.762 1.00 97.62  ? 21  SER N N   1 
ATOM 7123 C CA  . SER E 5 21  ? 128.623 141.112 172.364 1.00 94.67  ? 21  SER N CA  1 
ATOM 7124 C C   . SER E 5 21  ? 128.086 139.688 172.354 1.00 95.89  ? 21  SER N C   1 
ATOM 7125 O O   . SER E 5 21  ? 127.325 139.292 173.241 1.00 98.69  ? 21  SER N O   1 
ATOM 7126 C CB  . SER E 5 21  ? 129.824 141.208 173.306 1.00 97.25  ? 21  SER N CB  1 
ATOM 7127 O OG  . SER E 5 21  ? 129.403 141.352 174.651 1.00 98.12  ? 21  SER N OG  1 
ATOM 7128 N N   . CYS E 5 22  ? 128.494 138.922 171.347 1.00 92.74  ? 22  CYS N N   1 
ATOM 7129 C CA  . CYS E 5 22  ? 128.040 137.553 171.155 1.00 95.51  ? 22  CYS N CA  1 
ATOM 7130 C C   . CYS E 5 22  ? 129.229 136.648 170.877 1.00 96.72  ? 22  CYS N C   1 
ATOM 7131 O O   . CYS E 5 22  ? 130.130 137.009 170.115 1.00 98.04  ? 22  CYS N O   1 
ATOM 7132 C CB  . CYS E 5 22  ? 127.034 137.467 170.004 1.00 98.78  ? 22  CYS N CB  1 
ATOM 7133 S SG  . CYS E 5 22  ? 126.928 135.856 169.207 1.00 111.74 ? 22  CYS N SG  1 
ATOM 7134 N N   . ALA E 5 23  ? 129.221 135.467 171.487 1.00 96.59  ? 23  ALA N N   1 
ATOM 7135 C CA  . ALA E 5 23  ? 130.315 134.517 171.376 1.00 94.98  ? 23  ALA N CA  1 
ATOM 7136 C C   . ALA E 5 23  ? 129.791 133.177 170.882 1.00 94.42  ? 23  ALA N C   1 
ATOM 7137 O O   . ALA E 5 23  ? 128.605 132.867 171.020 1.00 94.84  ? 23  ALA N O   1 
ATOM 7138 C CB  . ALA E 5 23  ? 131.034 134.332 172.717 1.00 92.16  ? 23  ALA N CB  1 
ATOM 7139 N N   . ALA E 5 24  ? 130.687 132.385 170.297 1.00 91.35  ? 24  ALA N N   1 
ATOM 7140 C CA  . ALA E 5 24  ? 130.317 131.104 169.718 1.00 88.77  ? 24  ALA N CA  1 
ATOM 7141 C C   . ALA E 5 24  ? 131.444 130.102 169.919 1.00 89.69  ? 24  ALA N C   1 
ATOM 7142 O O   . ALA E 5 24  ? 132.603 130.467 170.125 1.00 94.26  ? 24  ALA N O   1 
ATOM 7143 C CB  . ALA E 5 24  ? 129.987 131.234 168.227 1.00 85.09  ? 24  ALA N CB  1 
ATOM 7144 N N   . SER E 5 25  ? 131.082 128.824 169.853 1.00 86.25  ? 25  SER N N   1 
ATOM 7145 C CA  . SER E 5 25  ? 132.038 127.740 170.009 1.00 85.62  ? 25  SER N CA  1 
ATOM 7146 C C   . SER E 5 25  ? 131.590 126.571 169.147 1.00 85.25  ? 25  SER N C   1 
ATOM 7147 O O   . SER E 5 25  ? 130.428 126.483 168.745 1.00 86.55  ? 25  SER N O   1 
ATOM 7148 C CB  . SER E 5 25  ? 132.170 127.312 171.473 1.00 89.24  ? 25  SER N CB  1 
ATOM 7149 O OG  . SER E 5 25  ? 130.900 127.241 172.095 1.00 90.20  ? 25  SER N OG  1 
ATOM 7150 N N   . GLY E 5 26  ? 132.525 125.670 168.867 1.00 86.14  ? 26  GLY N N   1 
ATOM 7151 C CA  . GLY E 5 26  ? 132.201 124.531 168.035 1.00 83.90  ? 26  GLY N CA  1 
ATOM 7152 C C   . GLY E 5 26  ? 132.519 124.748 166.571 1.00 86.06  ? 26  GLY N C   1 
ATOM 7153 O O   . GLY E 5 26  ? 133.641 124.496 166.122 1.00 92.33  ? 26  GLY N O   1 
ATOM 7154 N N   . PHE E 5 27  ? 131.513 125.192 165.823 1.00 82.60  ? 27  PHE N N   1 
ATOM 7155 C CA  . PHE E 5 27  ? 131.593 125.338 164.378 1.00 82.21  ? 27  PHE N CA  1 
ATOM 7156 C C   . PHE E 5 27  ? 132.640 126.372 163.965 1.00 85.86  ? 27  PHE N C   1 
ATOM 7157 O O   . PHE E 5 27  ? 132.981 127.292 164.714 1.00 87.37  ? 27  PHE N O   1 
ATOM 7158 C CB  . PHE E 5 27  ? 130.225 125.730 163.811 1.00 82.51  ? 27  PHE N CB  1 
ATOM 7159 C CG  . PHE E 5 27  ? 129.644 126.990 164.402 1.00 83.68  ? 27  PHE N CG  1 
ATOM 7160 C CD1 . PHE E 5 27  ? 128.902 126.954 165.573 1.00 86.17  ? 27  PHE N CD1 1 
ATOM 7161 C CD2 . PHE E 5 27  ? 129.800 128.203 163.759 1.00 83.12  ? 27  PHE N CD2 1 
ATOM 7162 C CE1 . PHE E 5 27  ? 128.362 128.106 166.105 1.00 87.59  ? 27  PHE N CE1 1 
ATOM 7163 C CE2 . PHE E 5 27  ? 129.261 129.357 164.285 1.00 82.30  ? 27  PHE N CE2 1 
ATOM 7164 C CZ  . PHE E 5 27  ? 128.541 129.309 165.457 1.00 86.08  ? 27  PHE N CZ  1 
ATOM 7165 N N   . THR E 5 28  ? 133.156 126.201 162.749 1.00 86.37  ? 28  THR N N   1 
ATOM 7166 C CA  . THR E 5 28  ? 134.110 127.142 162.183 1.00 84.55  ? 28  THR N CA  1 
ATOM 7167 C C   . THR E 5 28  ? 133.417 128.454 161.828 1.00 85.68  ? 28  THR N C   1 
ATOM 7168 O O   . THR E 5 28  ? 132.195 128.527 161.681 1.00 89.96  ? 28  THR N O   1 
ATOM 7169 C CB  . THR E 5 28  ? 134.781 126.556 160.942 1.00 84.17  ? 28  THR N CB  1 
ATOM 7170 O OG1 . THR E 5 28  ? 133.969 126.815 159.791 1.00 85.20  ? 28  THR N OG1 1 
ATOM 7171 C CG2 . THR E 5 28  ? 134.967 125.057 161.094 1.00 83.62  ? 28  THR N CG2 1 
ATOM 7172 N N   . PHE E 5 29  ? 134.224 129.503 161.675 1.00 79.69  ? 29  PHE N N   1 
ATOM 7173 C CA  . PHE E 5 29  ? 133.714 130.863 161.630 1.00 77.59  ? 29  PHE N CA  1 
ATOM 7174 C C   . PHE E 5 29  ? 133.996 131.612 160.338 1.00 79.85  ? 29  PHE N C   1 
ATOM 7175 O O   . PHE E 5 29  ? 133.362 132.647 160.108 1.00 82.64  ? 29  PHE N O   1 
ATOM 7176 C CB  . PHE E 5 29  ? 134.298 131.678 162.792 1.00 83.22  ? 29  PHE N CB  1 
ATOM 7177 C CG  . PHE E 5 29  ? 133.278 132.438 163.576 1.00 84.06  ? 29  PHE N CG  1 
ATOM 7178 C CD1 . PHE E 5 29  ? 132.417 131.784 164.435 1.00 87.27  ? 29  PHE N CD1 1 
ATOM 7179 C CD2 . PHE E 5 29  ? 133.200 133.814 163.474 1.00 84.68  ? 29  PHE N CD2 1 
ATOM 7180 C CE1 . PHE E 5 29  ? 131.485 132.489 165.166 1.00 89.84  ? 29  PHE N CE1 1 
ATOM 7181 C CE2 . PHE E 5 29  ? 132.272 134.523 164.201 1.00 85.41  ? 29  PHE N CE2 1 
ATOM 7182 C CZ  . PHE E 5 29  ? 131.417 133.862 165.049 1.00 89.42  ? 29  PHE N CZ  1 
ATOM 7183 N N   . SER E 5 30  ? 134.944 131.153 159.515 1.00 82.89  ? 30  SER N N   1 
ATOM 7184 C CA  . SER E 5 30  ? 135.268 131.864 158.280 1.00 84.03  ? 30  SER N CA  1 
ATOM 7185 C C   . SER E 5 30  ? 134.099 131.832 157.305 1.00 83.70  ? 30  SER N C   1 
ATOM 7186 O O   . SER E 5 30  ? 133.807 132.830 156.638 1.00 86.73  ? 30  SER N O   1 
ATOM 7187 C CB  . SER E 5 30  ? 136.519 131.262 157.641 1.00 85.88  ? 30  SER N CB  1 
ATOM 7188 O OG  . SER E 5 30  ? 137.681 131.597 158.380 1.00 83.33  ? 30  SER N OG  1 
ATOM 7189 N N   . ASN E 5 31  ? 133.425 130.697 157.217 1.00 79.85  ? 31  ASN N N   1 
ATOM 7190 C CA  . ASN E 5 31  ? 132.174 130.556 156.491 1.00 75.96  ? 31  ASN N CA  1 
ATOM 7191 C C   . ASN E 5 31  ? 131.039 130.920 157.449 1.00 75.57  ? 31  ASN N C   1 
ATOM 7192 O O   . ASN E 5 31  ? 131.285 131.546 158.484 1.00 78.60  ? 31  ASN N O   1 
ATOM 7193 C CB  . ASN E 5 31  ? 132.075 129.137 155.936 1.00 79.33  ? 31  ASN N CB  1 
ATOM 7194 C CG  . ASN E 5 31  ? 133.420 128.598 155.497 1.00 83.65  ? 31  ASN N CG  1 
ATOM 7195 O OD1 . ASN E 5 31  ? 134.045 129.128 154.580 1.00 84.57  ? 31  ASN N OD1 1 
ATOM 7196 N ND2 . ASN E 5 31  ? 133.877 127.542 156.157 1.00 84.39  ? 31  ASN N ND2 1 
ATOM 7197 N N   . TYR E 5 32  ? 129.799 130.548 157.115 1.00 74.46  ? 32  TYR N N   1 
ATOM 7198 C CA  . TYR E 5 32  ? 128.642 130.647 158.012 1.00 75.41  ? 32  TYR N CA  1 
ATOM 7199 C C   . TYR E 5 32  ? 128.380 132.097 158.428 1.00 75.07  ? 32  TYR N C   1 
ATOM 7200 O O   . TYR E 5 32  ? 128.660 132.508 159.555 1.00 78.62  ? 32  TYR N O   1 
ATOM 7201 C CB  . TYR E 5 32  ? 128.801 129.752 159.251 1.00 77.24  ? 32  TYR N CB  1 
ATOM 7202 C CG  . TYR E 5 32  ? 129.193 128.340 158.930 1.00 78.77  ? 32  TYR N CG  1 
ATOM 7203 C CD1 . TYR E 5 32  ? 128.237 127.402 158.594 1.00 76.48  ? 32  TYR N CD1 1 
ATOM 7204 C CD2 . TYR E 5 32  ? 130.522 127.944 158.959 1.00 84.27  ? 32  TYR N CD2 1 
ATOM 7205 C CE1 . TYR E 5 32  ? 128.587 126.113 158.296 1.00 80.38  ? 32  TYR N CE1 1 
ATOM 7206 C CE2 . TYR E 5 32  ? 130.887 126.654 158.654 1.00 84.59  ? 32  TYR N CE2 1 
ATOM 7207 C CZ  . TYR E 5 32  ? 129.913 125.741 158.323 1.00 83.20  ? 32  TYR N CZ  1 
ATOM 7208 O OH  . TYR E 5 32  ? 130.268 124.451 158.017 1.00 82.35  ? 32  TYR N OH  1 
ATOM 7209 N N   . LYS E 5 33  ? 127.921 132.876 157.450 1.00 71.09  ? 33  LYS N N   1 
ATOM 7210 C CA  . LYS E 5 33  ? 127.517 134.251 157.712 1.00 69.58  ? 33  LYS N CA  1 
ATOM 7211 C C   . LYS E 5 33  ? 126.424 134.293 158.775 1.00 69.84  ? 33  LYS N C   1 
ATOM 7212 O O   . LYS E 5 33  ? 125.567 133.409 158.848 1.00 75.47  ? 33  LYS N O   1 
ATOM 7213 C CB  . LYS E 5 33  ? 127.067 134.917 156.404 1.00 73.29  ? 33  LYS N CB  1 
ATOM 7214 C CG  . LYS E 5 33  ? 125.599 134.787 156.029 1.00 72.95  ? 33  LYS N CG  1 
ATOM 7215 C CD  . LYS E 5 33  ? 125.260 135.615 154.805 1.00 71.61  ? 33  LYS N CD  1 
ATOM 7216 C CE  . LYS E 5 33  ? 123.978 136.399 155.012 1.00 72.23  ? 33  LYS N CE  1 
ATOM 7217 N NZ  . LYS E 5 33  ? 123.683 137.288 153.857 1.00 72.76  ? 33  LYS N NZ  1 
ATOM 7218 N N   . MET E 5 34  ? 126.514 135.267 159.674 1.00 65.46  ? 34  MET N N   1 
ATOM 7219 C CA  . MET E 5 34  ? 125.601 135.338 160.804 1.00 71.39  ? 34  MET N CA  1 
ATOM 7220 C C   . MET E 5 34  ? 124.878 136.676 160.831 1.00 70.16  ? 34  MET N C   1 
ATOM 7221 O O   . MET E 5 34  ? 125.469 137.722 160.548 1.00 71.52  ? 34  MET N O   1 
ATOM 7222 C CB  . MET E 5 34  ? 126.320 135.094 162.138 1.00 71.28  ? 34  MET N CB  1 
ATOM 7223 C CG  . MET E 5 34  ? 127.259 133.904 162.124 1.00 75.87  ? 34  MET N CG  1 
ATOM 7224 S SD  . MET E 5 34  ? 128.208 133.616 163.628 1.00 97.81  ? 34  MET N SD  1 
ATOM 7225 C CE  . MET E 5 34  ? 128.086 135.191 164.462 1.00 87.69  ? 34  MET N CE  1 
ATOM 7226 N N   . ASN E 5 35  ? 123.596 136.624 161.175 1.00 65.57  ? 35  ASN N N   1 
ATOM 7227 C CA  . ASN E 5 35  ? 122.696 137.766 161.157 1.00 62.65  ? 35  ASN N CA  1 
ATOM 7228 C C   . ASN E 5 35  ? 122.394 138.203 162.585 1.00 66.64  ? 35  ASN N C   1 
ATOM 7229 O O   . ASN E 5 35  ? 122.959 137.689 163.553 1.00 71.31  ? 35  ASN N O   1 
ATOM 7230 C CB  . ASN E 5 35  ? 121.388 137.441 160.423 1.00 64.29  ? 35  ASN N CB  1 
ATOM 7231 C CG  . ASN E 5 35  ? 121.582 136.678 159.112 1.00 69.42  ? 35  ASN N CG  1 
ATOM 7232 O OD1 . ASN E 5 35  ? 120.657 136.016 158.653 1.00 75.41  ? 35  ASN N OD1 1 
ATOM 7233 N ND2 . ASN E 5 35  ? 122.727 136.847 158.459 1.00 72.23  ? 35  ASN N ND2 1 
ATOM 7234 N N   . TRP E 5 36  ? 121.489 139.170 162.709 1.00 66.10  ? 36  TRP N N   1 
ATOM 7235 C CA  . TRP E 5 36  ? 120.949 139.594 163.993 1.00 66.73  ? 36  TRP N CA  1 
ATOM 7236 C C   . TRP E 5 36  ? 119.435 139.636 163.895 1.00 70.89  ? 36  TRP N C   1 
ATOM 7237 O O   . TRP E 5 36  ? 118.889 140.268 162.986 1.00 71.87  ? 36  TRP N O   1 
ATOM 7238 C CB  . TRP E 5 36  ? 121.478 140.966 164.406 1.00 67.73  ? 36  TRP N CB  1 
ATOM 7239 C CG  . TRP E 5 36  ? 122.795 140.927 165.093 1.00 70.76  ? 36  TRP N CG  1 
ATOM 7240 C CD1 . TRP E 5 36  ? 123.987 141.349 164.592 1.00 74.78  ? 36  TRP N CD1 1 
ATOM 7241 C CD2 . TRP E 5 36  ? 123.061 140.444 166.411 1.00 72.28  ? 36  TRP N CD2 1 
ATOM 7242 N NE1 . TRP E 5 36  ? 124.981 141.160 165.516 1.00 76.39  ? 36  TRP N NE1 1 
ATOM 7243 C CE2 . TRP E 5 36  ? 124.438 140.605 166.643 1.00 74.63  ? 36  TRP N CE2 1 
ATOM 7244 C CE3 . TRP E 5 36  ? 122.268 139.894 167.421 1.00 77.73  ? 36  TRP N CE3 1 
ATOM 7245 C CZ2 . TRP E 5 36  ? 125.041 140.233 167.837 1.00 78.59  ? 36  TRP N CZ2 1 
ATOM 7246 C CZ3 . TRP E 5 36  ? 122.870 139.524 168.607 1.00 81.25  ? 36  TRP N CZ3 1 
ATOM 7247 C CH2 . TRP E 5 36  ? 124.244 139.694 168.804 1.00 80.37  ? 36  TRP N CH2 1 
ATOM 7248 N N   . VAL E 5 37  ? 118.759 138.967 164.823 1.00 73.23  ? 37  VAL N N   1 
ATOM 7249 C CA  . VAL E 5 37  ? 117.305 138.955 164.870 1.00 75.04  ? 37  VAL N CA  1 
ATOM 7250 C C   . VAL E 5 37  ? 116.847 139.332 166.268 1.00 74.76  ? 37  VAL N C   1 
ATOM 7251 O O   . VAL E 5 37  ? 117.408 138.869 167.266 1.00 75.92  ? 37  VAL N O   1 
ATOM 7252 C CB  . VAL E 5 37  ? 116.720 137.591 164.459 1.00 77.39  ? 37  VAL N CB  1 
ATOM 7253 C CG1 . VAL E 5 37  ? 116.649 137.493 162.951 1.00 80.23  ? 37  VAL N CG1 1 
ATOM 7254 C CG2 . VAL E 5 37  ? 117.550 136.465 165.033 1.00 74.73  ? 37  VAL N CG2 1 
ATOM 7255 N N   . ARG E 5 38  ? 115.824 140.175 166.334 1.00 74.87  ? 38  ARG N N   1 
ATOM 7256 C CA  . ARG E 5 38  ? 115.267 140.634 167.592 1.00 73.59  ? 38  ARG N CA  1 
ATOM 7257 C C   . ARG E 5 38  ? 113.767 140.386 167.600 1.00 74.72  ? 38  ARG N C   1 
ATOM 7258 O O   . ARG E 5 38  ? 113.117 140.368 166.551 1.00 77.86  ? 38  ARG N O   1 
ATOM 7259 C CB  . ARG E 5 38  ? 115.574 142.117 167.822 1.00 74.65  ? 38  ARG N CB  1 
ATOM 7260 C CG  . ARG E 5 38  ? 114.838 143.078 166.904 1.00 73.28  ? 38  ARG N CG  1 
ATOM 7261 C CD  . ARG E 5 38  ? 114.846 144.483 167.474 1.00 75.18  ? 38  ARG N CD  1 
ATOM 7262 N NE  . ARG E 5 38  ? 114.931 145.505 166.440 1.00 76.84  ? 38  ARG N NE  1 
ATOM 7263 C CZ  . ARG E 5 38  ? 113.984 146.397 166.193 1.00 80.40  ? 38  ARG N CZ  1 
ATOM 7264 N NH1 . ARG E 5 38  ? 112.854 146.411 166.879 1.00 83.32  ? 38  ARG N NH1 1 
ATOM 7265 N NH2 . ARG E 5 38  ? 114.175 147.297 165.234 1.00 82.06  ? 38  ARG N NH2 1 
ATOM 7266 N N   . GLN E 5 39  ? 113.224 140.163 168.793 1.00 73.41  ? 39  GLN N N   1 
ATOM 7267 C CA  . GLN E 5 39  ? 111.798 139.920 168.962 1.00 74.48  ? 39  GLN N CA  1 
ATOM 7268 C C   . GLN E 5 39  ? 111.304 140.869 170.042 1.00 79.48  ? 39  GLN N C   1 
ATOM 7269 O O   . GLN E 5 39  ? 111.794 140.840 171.177 1.00 82.51  ? 39  GLN N O   1 
ATOM 7270 C CB  . GLN E 5 39  ? 111.523 138.448 169.308 1.00 75.95  ? 39  GLN N CB  1 
ATOM 7271 C CG  . GLN E 5 39  ? 110.421 138.165 170.319 1.00 79.00  ? 39  GLN N CG  1 
ATOM 7272 C CD  . GLN E 5 39  ? 110.178 136.684 170.507 1.00 85.54  ? 39  GLN N CD  1 
ATOM 7273 O OE1 . GLN E 5 39  ? 110.640 135.863 169.716 1.00 89.25  ? 39  GLN N OE1 1 
ATOM 7274 N NE2 . GLN E 5 39  ? 109.451 136.332 171.562 1.00 85.92  ? 39  GLN N NE2 1 
ATOM 7275 N N   . ALA E 5 40  ? 110.396 141.747 169.670 1.00 82.48  ? 40  ALA N N   1 
ATOM 7276 C CA  . ALA E 5 40  ? 109.880 142.735 170.597 1.00 84.97  ? 40  ALA N CA  1 
ATOM 7277 C C   . ALA E 5 40  ? 108.866 142.090 171.537 1.00 86.97  ? 40  ALA N C   1 
ATOM 7278 O O   . ALA E 5 40  ? 108.245 141.082 171.189 1.00 86.98  ? 40  ALA N O   1 
ATOM 7279 C CB  . ALA E 5 40  ? 109.228 143.885 169.837 1.00 83.21  ? 40  ALA N CB  1 
ATOM 7280 N N   . PRO E 5 41  ? 108.694 142.637 172.745 1.00 87.56  ? 41  PRO N N   1 
ATOM 7281 C CA  . PRO E 5 41  ? 107.617 142.147 173.614 1.00 86.27  ? 41  PRO N CA  1 
ATOM 7282 C C   . PRO E 5 41  ? 106.252 142.471 173.033 1.00 83.78  ? 41  PRO N C   1 
ATOM 7283 O O   . PRO E 5 41  ? 105.843 143.635 172.988 1.00 83.06  ? 41  PRO N O   1 
ATOM 7284 C CB  . PRO E 5 41  ? 107.865 142.881 174.939 1.00 86.66  ? 41  PRO N CB  1 
ATOM 7285 C CG  . PRO E 5 41  ? 108.718 144.054 174.579 1.00 87.36  ? 41  PRO N CG  1 
ATOM 7286 C CD  . PRO E 5 41  ? 109.570 143.594 173.444 1.00 85.06  ? 41  PRO N CD  1 
ATOM 7287 N N   . GLY E 5 42  ? 105.543 141.443 172.583 1.00 82.67  ? 42  GLY N N   1 
ATOM 7288 C CA  . GLY E 5 42  ? 104.286 141.634 171.896 1.00 82.92  ? 42  GLY N CA  1 
ATOM 7289 C C   . GLY E 5 42  ? 104.373 141.650 170.388 1.00 83.05  ? 42  GLY N C   1 
ATOM 7290 O O   . GLY E 5 42  ? 103.406 142.060 169.735 1.00 87.17  ? 42  GLY N O   1 
ATOM 7291 N N   . LYS E 5 43  ? 105.495 141.225 169.812 1.00 79.06  ? 43  LYS N N   1 
ATOM 7292 C CA  . LYS E 5 43  ? 105.663 141.202 168.368 1.00 77.12  ? 43  LYS N CA  1 
ATOM 7293 C C   . LYS E 5 43  ? 106.414 139.940 167.970 1.00 78.65  ? 43  LYS N C   1 
ATOM 7294 O O   . LYS E 5 43  ? 106.952 139.217 168.812 1.00 83.66  ? 43  LYS N O   1 
ATOM 7295 C CB  . LYS E 5 43  ? 106.400 142.449 167.869 1.00 75.51  ? 43  LYS N CB  1 
ATOM 7296 N N   . GLY E 5 44  ? 106.438 139.677 166.668 1.00 75.30  ? 44  GLY N N   1 
ATOM 7297 C CA  . GLY E 5 44  ? 107.145 138.536 166.129 1.00 74.20  ? 44  GLY N CA  1 
ATOM 7298 C C   . GLY E 5 44  ? 108.621 138.821 165.928 1.00 79.52  ? 44  GLY N C   1 
ATOM 7299 O O   . GLY E 5 44  ? 109.153 139.859 166.325 1.00 82.61  ? 44  GLY N O   1 
ATOM 7300 N N   . LEU E 5 45  ? 109.292 137.865 165.294 1.00 78.64  ? 45  LEU N N   1 
ATOM 7301 C CA  . LEU E 5 45  ? 110.723 137.976 165.050 1.00 77.10  ? 45  LEU N CA  1 
ATOM 7302 C C   . LEU E 5 45  ? 111.001 138.885 163.860 1.00 77.15  ? 45  LEU N C   1 
ATOM 7303 O O   . LEU E 5 45  ? 110.284 138.854 162.856 1.00 80.48  ? 45  LEU N O   1 
ATOM 7304 C CB  . LEU E 5 45  ? 111.328 136.596 164.805 1.00 75.57  ? 45  LEU N CB  1 
ATOM 7305 C CG  . LEU E 5 45  ? 111.582 135.767 166.061 1.00 76.91  ? 45  LEU N CG  1 
ATOM 7306 C CD1 . LEU E 5 45  ? 110.410 134.843 166.350 1.00 76.04  ? 45  LEU N CD1 1 
ATOM 7307 C CD2 . LEU E 5 45  ? 112.866 134.978 165.923 1.00 78.50  ? 45  LEU N CD2 1 
ATOM 7308 N N   . GLU E 5 46  ? 112.050 139.696 163.975 1.00 71.96  ? 46  GLU N N   1 
ATOM 7309 C CA  . GLU E 5 46  ? 112.407 140.643 162.931 1.00 74.21  ? 46  GLU N CA  1 
ATOM 7310 C C   . GLU E 5 46  ? 113.919 140.722 162.813 1.00 75.18  ? 46  GLU N C   1 
ATOM 7311 O O   . GLU E 5 46  ? 114.642 140.588 163.801 1.00 79.01  ? 46  GLU N O   1 
ATOM 7312 C CB  . GLU E 5 46  ? 111.829 142.036 163.213 1.00 79.57  ? 46  GLU N CB  1 
ATOM 7313 C CG  . GLU E 5 46  ? 111.664 142.921 161.982 1.00 87.43  ? 46  GLU N CG  1 
ATOM 7314 C CD  . GLU E 5 46  ? 111.402 142.131 160.715 1.00 93.43  ? 46  GLU N CD  1 
ATOM 7315 O OE1 . GLU E 5 46  ? 110.269 141.633 160.543 1.00 97.62  ? 46  GLU N OE1 1 
ATOM 7316 O OE2 . GLU E 5 46  ? 112.329 142.016 159.886 1.00 93.44  ? 46  GLU N OE2 1 
ATOM 7317 N N   . TRP E 5 47  ? 114.386 140.957 161.592 1.00 72.98  ? 47  TRP N N   1 
ATOM 7318 C CA  . TRP E 5 47  ? 115.809 140.995 161.290 1.00 71.64  ? 47  TRP N CA  1 
ATOM 7319 C C   . TRP E 5 47  ? 116.372 142.402 161.455 1.00 73.84  ? 47  TRP N C   1 
ATOM 7320 O O   . TRP E 5 47  ? 115.697 143.392 161.161 1.00 77.23  ? 47  TRP N O   1 
ATOM 7321 C CB  . TRP E 5 47  ? 116.048 140.495 159.867 1.00 68.13  ? 47  TRP N CB  1 
ATOM 7322 C CG  . TRP E 5 47  ? 117.356 140.894 159.309 1.00 67.68  ? 47  TRP N CG  1 
ATOM 7323 C CD1 . TRP E 5 47  ? 118.562 140.345 159.599 1.00 69.94  ? 47  TRP N CD1 1 
ATOM 7324 C CD2 . TRP E 5 47  ? 117.604 141.947 158.375 1.00 67.47  ? 47  TRP N CD2 1 
ATOM 7325 N NE1 . TRP E 5 47  ? 119.551 140.982 158.893 1.00 69.40  ? 47  TRP N NE1 1 
ATOM 7326 C CE2 . TRP E 5 47  ? 118.988 141.976 158.138 1.00 70.22  ? 47  TRP N CE2 1 
ATOM 7327 C CE3 . TRP E 5 47  ? 116.786 142.861 157.707 1.00 70.74  ? 47  TRP N CE3 1 
ATOM 7328 C CZ2 . TRP E 5 47  ? 119.574 142.873 157.253 1.00 73.32  ? 47  TRP N CZ2 1 
ATOM 7329 C CZ3 . TRP E 5 47  ? 117.371 143.759 156.835 1.00 72.57  ? 47  TRP N CZ3 1 
ATOM 7330 C CH2 . TRP E 5 47  ? 118.753 143.761 156.618 1.00 73.41  ? 47  TRP N CH2 1 
ATOM 7331 N N   . VAL E 5 48  ? 117.620 142.483 161.920 1.00 70.23  ? 48  VAL N N   1 
ATOM 7332 C CA  . VAL E 5 48  ? 118.305 143.754 162.144 1.00 69.03  ? 48  VAL N CA  1 
ATOM 7333 C C   . VAL E 5 48  ? 119.403 143.986 161.107 1.00 69.17  ? 48  VAL N C   1 
ATOM 7334 O O   . VAL E 5 48  ? 119.337 144.937 160.326 1.00 71.32  ? 48  VAL N O   1 
ATOM 7335 C CB  . VAL E 5 48  ? 118.865 143.833 163.582 1.00 74.69  ? 48  VAL N CB  1 
ATOM 7336 C CG1 . VAL E 5 48  ? 119.775 145.041 163.748 1.00 77.92  ? 48  VAL N CG1 1 
ATOM 7337 C CG2 . VAL E 5 48  ? 117.730 143.876 164.584 1.00 74.91  ? 48  VAL N CG2 1 
ATOM 7338 N N   . SER E 5 49  ? 120.419 143.124 161.080 1.00 68.20  ? 49  SER N N   1 
ATOM 7339 C CA  . SER E 5 49  ? 121.576 143.346 160.222 1.00 67.13  ? 49  SER N CA  1 
ATOM 7340 C C   . SER E 5 49  ? 122.287 142.024 159.983 1.00 66.35  ? 49  SER N C   1 
ATOM 7341 O O   . SER E 5 49  ? 122.128 141.067 160.744 1.00 71.98  ? 49  SER N O   1 
ATOM 7342 C CB  . SER E 5 49  ? 122.541 144.364 160.832 1.00 71.24  ? 49  SER N CB  1 
ATOM 7343 O OG  . SER E 5 49  ? 123.726 144.464 160.061 1.00 76.70  ? 49  SER N OG  1 
ATOM 7344 N N   . ASP E 5 50  ? 123.076 141.986 158.912 1.00 63.96  ? 50  ASP N N   1 
ATOM 7345 C CA  . ASP E 5 50  ? 123.797 140.784 158.528 1.00 64.39  ? 50  ASP N CA  1 
ATOM 7346 C C   . ASP E 5 50  ? 125.185 141.157 158.036 1.00 68.77  ? 50  ASP N C   1 
ATOM 7347 O O   . ASP E 5 50  ? 125.427 142.274 157.574 1.00 73.84  ? 50  ASP N O   1 
ATOM 7348 C CB  . ASP E 5 50  ? 123.061 139.997 157.440 1.00 68.09  ? 50  ASP N CB  1 
ATOM 7349 C CG  . ASP E 5 50  ? 122.523 140.882 156.340 1.00 74.04  ? 50  ASP N CG  1 
ATOM 7350 O OD1 . ASP E 5 50  ? 122.672 142.115 156.441 1.00 74.88  ? 50  ASP N OD1 1 
ATOM 7351 O OD2 . ASP E 5 50  ? 121.947 140.345 155.371 1.00 76.05  ? 50  ASP N OD2 1 
ATOM 7352 N N   . ILE E 5 51  ? 126.099 140.195 158.140 1.00 68.24  ? 51  ILE N N   1 
ATOM 7353 C CA  . ILE E 5 51  ? 127.468 140.352 157.674 1.00 68.61  ? 51  ILE N CA  1 
ATOM 7354 C C   . ILE E 5 51  ? 127.801 139.156 156.792 1.00 67.88  ? 51  ILE N C   1 
ATOM 7355 O O   . ILE E 5 51  ? 127.150 138.112 156.852 1.00 69.58  ? 51  ILE N O   1 
ATOM 7356 C CB  . ILE E 5 51  ? 128.467 140.496 158.848 1.00 69.34  ? 51  ILE N CB  1 
ATOM 7357 C CG1 . ILE E 5 51  ? 129.585 141.472 158.486 1.00 70.77  ? 51  ILE N CG1 1 
ATOM 7358 C CG2 . ILE E 5 51  ? 129.026 139.151 159.293 1.00 73.16  ? 51  ILE N CG2 1 
ATOM 7359 C CD1 . ILE E 5 51  ? 130.416 141.901 159.672 1.00 75.46  ? 51  ILE N CD1 1 
ATOM 7360 N N   . SER E 5 52  ? 128.800 139.334 155.937 1.00 69.82  ? 52  SER N N   1 
ATOM 7361 C CA  . SER E 5 52  ? 129.171 138.310 154.974 1.00 73.80  ? 52  SER N CA  1 
ATOM 7362 C C   . SER E 5 52  ? 130.155 137.335 155.616 1.00 75.05  ? 52  SER N C   1 
ATOM 7363 O O   . SER E 5 52  ? 130.437 137.404 156.814 1.00 75.69  ? 52  SER N O   1 
ATOM 7364 C CB  . SER E 5 52  ? 129.742 138.953 153.713 1.00 77.55  ? 52  SER N CB  1 
ATOM 7365 O OG  . SER E 5 52  ? 131.132 139.192 153.848 1.00 79.97  ? 52  SER N OG  1 
ATOM 7366 N N   . GLN E 5 53  ? 130.678 136.401 154.821 1.00 76.52  ? 53  GLN N N   1 
ATOM 7367 C CA  . GLN E 5 53  ? 131.619 135.419 155.350 1.00 79.21  ? 53  GLN N CA  1 
ATOM 7368 C C   . GLN E 5 53  ? 132.964 136.059 155.669 1.00 82.12  ? 53  GLN N C   1 
ATOM 7369 O O   . GLN E 5 53  ? 133.509 135.871 156.763 1.00 84.10  ? 53  GLN N O   1 
ATOM 7370 C CB  . GLN E 5 53  ? 131.792 134.272 154.354 1.00 83.92  ? 53  GLN N CB  1 
ATOM 7371 C CG  . GLN E 5 53  ? 130.485 133.702 153.830 1.00 86.68  ? 53  GLN N CG  1 
ATOM 7372 C CD  . GLN E 5 53  ? 130.153 134.193 152.434 1.00 91.74  ? 53  GLN N CD  1 
ATOM 7373 O OE1 . GLN E 5 53  ? 130.666 135.218 151.985 1.00 94.66  ? 53  GLN N OE1 1 
ATOM 7374 N NE2 . GLN E 5 53  ? 129.289 133.462 151.740 1.00 88.08  ? 53  GLN N NE2 1 
ATOM 7375 N N   . SER E 5 54  ? 133.518 136.818 154.723 1.00 83.46  ? 54  SER N N   1 
ATOM 7376 C CA  . SER E 5 54  ? 134.784 137.499 154.965 1.00 81.39  ? 54  SER N CA  1 
ATOM 7377 C C   . SER E 5 54  ? 134.603 138.714 155.864 1.00 77.34  ? 54  SER N C   1 
ATOM 7378 O O   . SER E 5 54  ? 135.397 138.936 156.783 1.00 76.28  ? 54  SER N O   1 
ATOM 7379 C CB  . SER E 5 54  ? 135.418 137.912 153.637 1.00 83.90  ? 54  SER N CB  1 
ATOM 7380 O OG  . SER E 5 54  ? 134.703 138.983 153.046 1.00 83.62  ? 54  SER N OG  1 
ATOM 7381 N N   . GLY E 5 55  ? 133.563 139.503 155.618 1.00 76.20  ? 55  GLY N N   1 
ATOM 7382 C CA  . GLY E 5 55  ? 133.335 140.711 156.381 1.00 75.04  ? 55  GLY N CA  1 
ATOM 7383 C C   . GLY E 5 55  ? 133.316 141.943 155.505 1.00 76.78  ? 55  GLY N C   1 
ATOM 7384 O O   . GLY E 5 55  ? 133.532 143.059 155.986 1.00 80.62  ? 55  GLY N O   1 
ATOM 7385 N N   . ALA E 5 56  ? 133.058 141.752 154.212 1.00 74.87  ? 56  ALA N N   1 
ATOM 7386 C CA  . ALA E 5 56  ? 133.070 142.859 153.265 1.00 78.88  ? 56  ALA N CA  1 
ATOM 7387 C C   . ALA E 5 56  ? 131.684 143.449 153.030 1.00 79.36  ? 56  ALA N C   1 
ATOM 7388 O O   . ALA E 5 56  ? 131.547 144.671 152.912 1.00 80.53  ? 56  ALA N O   1 
ATOM 7389 C CB  . ALA E 5 56  ? 133.670 142.404 151.933 1.00 78.58  ? 56  ALA N CB  1 
ATOM 7390 N N   . SER E 5 57  ? 130.654 142.612 152.959 1.00 76.43  ? 57  SER N N   1 
ATOM 7391 C CA  . SER E 5 57  ? 129.300 143.052 152.646 1.00 71.84  ? 57  SER N CA  1 
ATOM 7392 C C   . SER E 5 57  ? 128.479 143.104 153.924 1.00 67.88  ? 57  SER N C   1 
ATOM 7393 O O   . SER E 5 57  ? 128.224 142.066 154.544 1.00 69.02  ? 57  SER N O   1 
ATOM 7394 C CB  . SER E 5 57  ? 128.643 142.120 151.628 1.00 71.22  ? 57  SER N CB  1 
ATOM 7395 O OG  . SER E 5 57  ? 127.245 142.341 151.571 1.00 73.91  ? 57  SER N OG  1 
ATOM 7396 N N   . ILE E 5 58  ? 128.065 144.307 154.311 1.00 64.47  ? 58  ILE N N   1 
ATOM 7397 C CA  . ILE E 5 58  ? 127.239 144.527 155.490 1.00 62.74  ? 58  ILE N CA  1 
ATOM 7398 C C   . ILE E 5 58  ? 125.968 145.237 155.050 1.00 62.02  ? 58  ILE N C   1 
ATOM 7399 O O   . ILE E 5 58  ? 126.030 146.219 154.303 1.00 62.82  ? 58  ILE N O   1 
ATOM 7400 C CB  . ILE E 5 58  ? 127.969 145.354 156.565 1.00 67.06  ? 58  ILE N CB  1 
ATOM 7401 C CG1 . ILE E 5 58  ? 129.392 144.839 156.779 1.00 70.66  ? 58  ILE N CG1 1 
ATOM 7402 C CG2 . ILE E 5 58  ? 127.210 145.299 157.875 1.00 70.50  ? 58  ILE N CG2 1 
ATOM 7403 C CD1 . ILE E 5 58  ? 130.468 145.760 156.241 1.00 73.61  ? 58  ILE N CD1 1 
ATOM 7404 N N   . SER E 5 59  ? 124.821 144.743 155.505 1.00 60.47  ? 59  SER N N   1 
ATOM 7405 C CA  . SER E 5 59  ? 123.536 145.347 155.193 1.00 63.16  ? 59  SER N CA  1 
ATOM 7406 C C   . SER E 5 59  ? 122.725 145.506 156.468 1.00 65.17  ? 59  SER N C   1 
ATOM 7407 O O   . SER E 5 59  ? 122.941 144.798 157.453 1.00 67.58  ? 59  SER N O   1 
ATOM 7408 C CB  . SER E 5 59  ? 122.749 144.515 154.177 1.00 67.29  ? 59  SER N CB  1 
ATOM 7409 O OG  . SER E 5 59  ? 121.881 143.608 154.827 1.00 71.10  ? 59  SER N OG  1 
ATOM 7410 N N   . TYR E 5 60  ? 121.796 146.457 156.444 1.00 65.48  ? 60  TYR N N   1 
ATOM 7411 C CA  . TYR E 5 60  ? 120.961 146.755 157.598 1.00 66.25  ? 60  TYR N CA  1 
ATOM 7412 C C   . TYR E 5 60  ? 119.545 147.043 157.124 1.00 67.42  ? 60  TYR N C   1 
ATOM 7413 O O   . TYR E 5 60  ? 119.306 147.307 155.945 1.00 72.76  ? 60  TYR N O   1 
ATOM 7414 C CB  . TYR E 5 60  ? 121.470 147.950 158.432 1.00 67.46  ? 60  TYR N CB  1 
ATOM 7415 C CG  . TYR E 5 60  ? 122.968 148.055 158.657 1.00 64.28  ? 60  TYR N CG  1 
ATOM 7416 C CD1 . TYR E 5 60  ? 123.825 148.506 157.660 1.00 67.46  ? 60  TYR N CD1 1 
ATOM 7417 C CD2 . TYR E 5 60  ? 123.520 147.702 159.879 1.00 65.90  ? 60  TYR N CD2 1 
ATOM 7418 C CE1 . TYR E 5 60  ? 125.182 148.599 157.875 1.00 70.69  ? 60  TYR N CE1 1 
ATOM 7419 C CE2 . TYR E 5 60  ? 124.875 147.788 160.102 1.00 69.50  ? 60  TYR N CE2 1 
ATOM 7420 C CZ  . TYR E 5 60  ? 125.702 148.241 159.099 1.00 73.10  ? 60  TYR N CZ  1 
ATOM 7421 O OH  . TYR E 5 60  ? 127.057 148.331 159.319 1.00 78.09  ? 60  TYR N OH  1 
ATOM 7422 N N   . THR E 5 61  ? 118.603 146.984 158.061 1.00 63.50  ? 61  THR N N   1 
ATOM 7423 C CA  . THR E 5 61  ? 117.223 147.306 157.747 1.00 65.97  ? 61  THR N CA  1 
ATOM 7424 C C   . THR E 5 61  ? 117.017 148.817 157.784 1.00 74.24  ? 61  THR N C   1 
ATOM 7425 O O   . THR E 5 61  ? 117.953 149.596 157.985 1.00 77.82  ? 61  THR N O   1 
ATOM 7426 C CB  . THR E 5 61  ? 116.270 146.603 158.707 1.00 69.05  ? 61  THR N CB  1 
ATOM 7427 O OG1 . THR E 5 61  ? 114.919 146.898 158.332 1.00 74.13  ? 61  THR N OG1 1 
ATOM 7428 C CG2 . THR E 5 61  ? 116.501 147.067 160.122 1.00 72.17  ? 61  THR N CG2 1 
ATOM 7429 N N   . GLY E 5 62  ? 115.767 149.236 157.577 1.00 76.78  ? 62  GLY N N   1 
ATOM 7430 C CA  . GLY E 5 62  ? 115.478 150.657 157.463 1.00 78.14  ? 62  GLY N CA  1 
ATOM 7431 C C   . GLY E 5 62  ? 115.656 151.419 158.763 1.00 76.64  ? 62  GLY N C   1 
ATOM 7432 O O   . GLY E 5 62  ? 116.164 152.543 158.768 1.00 75.56  ? 62  GLY N O   1 
ATOM 7433 N N   . SER E 5 63  ? 115.254 150.821 159.878 1.00 73.02  ? 63  SER N N   1 
ATOM 7434 C CA  . SER E 5 63  ? 115.252 151.511 161.158 1.00 73.40  ? 63  SER N CA  1 
ATOM 7435 C C   . SER E 5 63  ? 116.582 151.416 161.889 1.00 77.49  ? 63  SER N C   1 
ATOM 7436 O O   . SER E 5 63  ? 116.694 151.923 163.009 1.00 83.58  ? 63  SER N O   1 
ATOM 7437 C CB  . SER E 5 63  ? 114.138 150.956 162.049 1.00 74.72  ? 63  SER N CB  1 
ATOM 7438 O OG  . SER E 5 63  ? 113.004 150.601 161.279 1.00 79.80  ? 63  SER N OG  1 
ATOM 7439 N N   . VAL E 5 64  ? 117.590 150.787 161.286 1.00 78.17  ? 64  VAL N N   1 
ATOM 7440 C CA  . VAL E 5 64  ? 118.844 150.488 161.957 1.00 80.16  ? 64  VAL N CA  1 
ATOM 7441 C C   . VAL E 5 64  ? 120.025 151.198 161.306 1.00 82.34  ? 64  VAL N C   1 
ATOM 7442 O O   . VAL E 5 64  ? 120.901 151.720 162.008 1.00 87.33  ? 64  VAL N O   1 
ATOM 7443 C CB  . VAL E 5 64  ? 119.071 148.958 162.015 1.00 78.88  ? 64  VAL N CB  1 
ATOM 7444 C CG1 . VAL E 5 64  ? 120.543 148.577 162.132 1.00 78.91  ? 64  VAL N CG1 1 
ATOM 7445 C CG2 . VAL E 5 64  ? 118.275 148.367 163.165 1.00 79.53  ? 64  VAL N CG2 1 
ATOM 7446 N N   . LYS E 5 65  ? 120.046 151.271 159.972 1.00 79.14  ? 65  LYS N N   1 
ATOM 7447 C CA  . LYS E 5 65  ? 121.201 151.796 159.251 1.00 79.87  ? 65  LYS N CA  1 
ATOM 7448 C C   . LYS E 5 65  ? 121.423 153.274 159.550 1.00 82.62  ? 65  LYS N C   1 
ATOM 7449 O O   . LYS E 5 65  ? 120.475 154.047 159.717 1.00 81.57  ? 65  LYS N O   1 
ATOM 7450 C CB  . LYS E 5 65  ? 121.036 151.582 157.744 1.00 78.79  ? 65  LYS N CB  1 
ATOM 7451 C CG  . LYS E 5 65  ? 119.799 152.215 157.127 1.00 80.73  ? 65  LYS N CG  1 
ATOM 7452 C CD  . LYS E 5 65  ? 119.492 151.609 155.766 1.00 81.58  ? 65  LYS N CD  1 
ATOM 7453 C CE  . LYS E 5 65  ? 120.692 151.689 154.835 1.00 83.60  ? 65  LYS N CE  1 
ATOM 7454 N NZ  . LYS E 5 65  ? 120.478 150.913 153.582 1.00 84.17  ? 65  LYS N NZ  1 
ATOM 7455 N N   . GLY E 5 66  ? 122.695 153.651 159.653 1.00 85.33  ? 66  GLY N N   1 
ATOM 7456 C CA  . GLY E 5 66  ? 123.076 154.958 160.131 1.00 84.78  ? 66  GLY N CA  1 
ATOM 7457 C C   . GLY E 5 66  ? 123.122 155.088 161.635 1.00 86.33  ? 66  GLY N C   1 
ATOM 7458 O O   . GLY E 5 66  ? 123.618 156.104 162.138 1.00 88.97  ? 66  GLY N O   1 
ATOM 7459 N N   . ARG E 5 67  ? 122.623 154.098 162.371 1.00 85.18  ? 67  ARG N N   1 
ATOM 7460 C CA  . ARG E 5 67  ? 122.587 154.127 163.827 1.00 87.48  ? 67  ARG N CA  1 
ATOM 7461 C C   . ARG E 5 67  ? 123.334 152.973 164.476 1.00 89.70  ? 67  ARG N C   1 
ATOM 7462 O O   . ARG E 5 67  ? 124.066 153.190 165.444 1.00 94.08  ? 67  ARG N O   1 
ATOM 7463 C CB  . ARG E 5 67  ? 121.131 154.128 164.318 1.00 87.70  ? 67  ARG N CB  1 
ATOM 7464 C CG  . ARG E 5 67  ? 120.162 154.876 163.413 1.00 85.15  ? 67  ARG N CG  1 
ATOM 7465 C CD  . ARG E 5 67  ? 118.724 154.679 163.843 1.00 83.50  ? 67  ARG N CD  1 
ATOM 7466 N NE  . ARG E 5 67  ? 118.594 154.604 165.292 1.00 88.61  ? 67  ARG N NE  1 
ATOM 7467 C CZ  . ARG E 5 67  ? 118.066 153.578 165.944 1.00 91.67  ? 67  ARG N CZ  1 
ATOM 7468 N NH1 . ARG E 5 67  ? 117.600 152.519 165.303 1.00 90.58  ? 67  ARG N NH1 1 
ATOM 7469 N NH2 . ARG E 5 67  ? 118.006 153.614 167.272 1.00 95.80  ? 67  ARG N NH2 1 
ATOM 7470 N N   . PHE E 5 68  ? 123.175 151.750 163.975 1.00 86.26  ? 68  PHE N N   1 
ATOM 7471 C CA  . PHE E 5 68  ? 123.809 150.575 164.554 1.00 84.75  ? 68  PHE N CA  1 
ATOM 7472 C C   . PHE E 5 68  ? 124.803 149.989 163.564 1.00 84.00  ? 68  PHE N C   1 
ATOM 7473 O O   . PHE E 5 68  ? 124.549 149.965 162.357 1.00 80.80  ? 68  PHE N O   1 
ATOM 7474 C CB  . PHE E 5 68  ? 122.785 149.501 164.935 1.00 86.84  ? 68  PHE N CB  1 
ATOM 7475 C CG  . PHE E 5 68  ? 121.737 149.964 165.909 1.00 92.93  ? 68  PHE N CG  1 
ATOM 7476 C CD1 . PHE E 5 68  ? 122.021 150.929 166.862 1.00 96.80  ? 68  PHE N CD1 1 
ATOM 7477 C CD2 . PHE E 5 68  ? 120.461 149.425 165.868 1.00 93.14  ? 68  PHE N CD2 1 
ATOM 7478 C CE1 . PHE E 5 68  ? 121.050 151.350 167.754 1.00 100.74 ? 68  PHE N CE1 1 
ATOM 7479 C CE2 . PHE E 5 68  ? 119.487 149.840 166.755 1.00 95.89  ? 68  PHE N CE2 1 
ATOM 7480 C CZ  . PHE E 5 68  ? 119.782 150.804 167.699 1.00 100.41 ? 68  PHE N CZ  1 
ATOM 7481 N N   . THR E 5 69  ? 125.935 149.518 164.078 1.00 89.93  ? 69  THR N N   1 
ATOM 7482 C CA  . THR E 5 69  ? 126.994 148.943 163.259 1.00 90.61  ? 69  THR N CA  1 
ATOM 7483 C C   . THR E 5 69  ? 127.369 147.580 163.817 1.00 90.28  ? 69  THR N C   1 
ATOM 7484 O O   . THR E 5 69  ? 127.579 147.438 165.025 1.00 92.07  ? 69  THR N O   1 
ATOM 7485 C CB  . THR E 5 69  ? 128.225 149.859 163.224 1.00 91.68  ? 69  THR N CB  1 
ATOM 7486 O OG1 . THR E 5 69  ? 127.825 151.185 162.854 1.00 93.42  ? 69  THR N OG1 1 
ATOM 7487 C CG2 . THR E 5 69  ? 129.248 149.349 162.218 1.00 86.30  ? 69  THR N CG2 1 
ATOM 7488 N N   . ILE E 5 70  ? 127.450 146.581 162.945 1.00 84.98  ? 70  ILE N N   1 
ATOM 7489 C CA  . ILE E 5 70  ? 127.851 145.243 163.344 1.00 82.17  ? 70  ILE N CA  1 
ATOM 7490 C C   . ILE E 5 70  ? 129.222 144.940 162.756 1.00 81.35  ? 70  ILE N C   1 
ATOM 7491 O O   . ILE E 5 70  ? 129.669 145.560 161.785 1.00 85.07  ? 70  ILE N O   1 
ATOM 7492 C CB  . ILE E 5 70  ? 126.817 144.178 162.927 1.00 82.12  ? 70  ILE N CB  1 
ATOM 7493 C CG1 . ILE E 5 70  ? 126.998 143.772 161.467 1.00 77.44  ? 70  ILE N CG1 1 
ATOM 7494 C CG2 . ILE E 5 70  ? 125.410 144.690 163.152 1.00 82.90  ? 70  ILE N CG2 1 
ATOM 7495 C CD1 . ILE E 5 70  ? 126.287 142.491 161.120 1.00 76.49  ? 70  ILE N CD1 1 
ATOM 7496 N N   . SER E 5 71  ? 129.907 143.985 163.376 1.00 80.71  ? 71  SER N N   1 
ATOM 7497 C CA  . SER E 5 71  ? 131.257 143.631 162.969 1.00 86.40  ? 71  SER N CA  1 
ATOM 7498 C C   . SER E 5 71  ? 131.548 142.212 163.425 1.00 89.36  ? 71  SER N C   1 
ATOM 7499 O O   . SER E 5 71  ? 130.895 141.685 164.328 1.00 91.11  ? 71  SER N O   1 
ATOM 7500 C CB  . SER E 5 71  ? 132.293 144.605 163.541 1.00 91.83  ? 71  SER N CB  1 
ATOM 7501 O OG  . SER E 5 71  ? 132.335 145.806 162.791 1.00 91.72  ? 71  SER N OG  1 
ATOM 7502 N N   . ARG E 5 72  ? 132.550 141.605 162.795 1.00 89.51  ? 72  ARG N N   1 
ATOM 7503 C CA  . ARG E 5 72  ? 132.911 140.223 163.070 1.00 86.43  ? 72  ARG N CA  1 
ATOM 7504 C C   . ARG E 5 72  ? 134.423 140.095 163.127 1.00 89.75  ? 72  ARG N C   1 
ATOM 7505 O O   . ARG E 5 72  ? 135.121 140.547 162.215 1.00 90.88  ? 72  ARG N O   1 
ATOM 7506 C CB  . ARG E 5 72  ? 132.344 139.287 161.998 1.00 84.38  ? 72  ARG N CB  1 
ATOM 7507 C CG  . ARG E 5 72  ? 133.000 137.920 161.943 1.00 85.12  ? 72  ARG N CG  1 
ATOM 7508 C CD  . ARG E 5 72  ? 133.465 137.598 160.540 1.00 82.55  ? 72  ARG N CD  1 
ATOM 7509 N NE  . ARG E 5 72  ? 132.346 137.280 159.663 1.00 81.17  ? 72  ARG N NE  1 
ATOM 7510 C CZ  . ARG E 5 72  ? 131.812 136.074 159.540 1.00 82.05  ? 72  ARG N CZ  1 
ATOM 7511 N NH1 . ARG E 5 72  ? 132.274 135.040 160.225 1.00 84.29  ? 72  ARG N NH1 1 
ATOM 7512 N NH2 . ARG E 5 72  ? 130.789 135.899 158.709 1.00 80.56  ? 72  ARG N NH2 1 
ATOM 7513 N N   . ASP E 5 73  ? 134.922 139.482 164.196 1.00 93.32  ? 73  ASP N N   1 
ATOM 7514 C CA  . ASP E 5 73  ? 136.338 139.155 164.341 1.00 96.11  ? 73  ASP N CA  1 
ATOM 7515 C C   . ASP E 5 73  ? 136.450 137.634 164.345 1.00 94.52  ? 73  ASP N C   1 
ATOM 7516 O O   . ASP E 5 73  ? 136.273 136.996 165.387 1.00 94.57  ? 73  ASP N O   1 
ATOM 7517 C CB  . ASP E 5 73  ? 136.921 139.766 165.611 1.00 97.33  ? 73  ASP N CB  1 
ATOM 7518 C CG  . ASP E 5 73  ? 138.415 140.001 165.511 1.00 100.53 ? 73  ASP N CG  1 
ATOM 7519 O OD1 . ASP E 5 73  ? 138.849 140.681 164.558 1.00 102.56 ? 73  ASP N OD1 1 
ATOM 7520 O OD2 . ASP E 5 73  ? 139.156 139.506 166.386 1.00 100.74 ? 73  ASP N OD2 1 
ATOM 7521 N N   . ASN E 5 74  ? 136.742 137.056 163.178 1.00 93.77  ? 74  ASN N N   1 
ATOM 7522 C CA  . ASN E 5 74  ? 136.796 135.605 163.055 1.00 91.37  ? 74  ASN N CA  1 
ATOM 7523 C C   . ASN E 5 74  ? 138.004 135.004 163.757 1.00 94.48  ? 74  ASN N C   1 
ATOM 7524 O O   . ASN E 5 74  ? 137.993 133.807 164.062 1.00 96.37  ? 74  ASN N O   1 
ATOM 7525 C CB  . ASN E 5 74  ? 136.796 135.199 161.581 1.00 87.95  ? 74  ASN N CB  1 
ATOM 7526 C CG  . ASN E 5 74  ? 137.673 136.090 160.732 1.00 96.32  ? 74  ASN N CG  1 
ATOM 7527 O OD1 . ASN E 5 74  ? 137.216 137.098 160.194 1.00 98.64  ? 74  ASN N OD1 1 
ATOM 7528 N ND2 . ASN E 5 74  ? 138.943 135.724 160.605 1.00 98.11  ? 74  ASN N ND2 1 
ATOM 7529 N N   . ALA E 5 75  ? 139.044 135.799 164.010 1.00 95.13  ? 75  ALA N N   1 
ATOM 7530 C CA  . ALA E 5 75  ? 140.181 135.301 164.774 1.00 97.70  ? 75  ALA N CA  1 
ATOM 7531 C C   . ALA E 5 75  ? 139.806 135.069 166.232 1.00 96.46  ? 75  ALA N C   1 
ATOM 7532 O O   . ALA E 5 75  ? 140.246 134.090 166.845 1.00 93.95  ? 75  ALA N O   1 
ATOM 7533 C CB  . ALA E 5 75  ? 141.354 136.275 164.668 1.00 97.95  ? 75  ALA N CB  1 
ATOM 7534 N N   . LYS E 5 76  ? 138.995 135.955 166.802 1.00 95.91  ? 76  LYS N N   1 
ATOM 7535 C CA  . LYS E 5 76  ? 138.592 135.854 168.197 1.00 95.18  ? 76  LYS N CA  1 
ATOM 7536 C C   . LYS E 5 76  ? 137.258 135.143 168.382 1.00 98.35  ? 76  LYS N C   1 
ATOM 7537 O O   . LYS E 5 76  ? 136.790 135.045 169.522 1.00 101.10 ? 76  LYS N O   1 
ATOM 7538 C CB  . LYS E 5 76  ? 138.521 137.248 168.827 1.00 92.57  ? 76  LYS N CB  1 
ATOM 7539 N N   . ASN E 5 77  ? 136.653 134.650 167.291 1.00 95.31  ? 77  ASN N N   1 
ATOM 7540 C CA  . ASN E 5 77  ? 135.369 133.933 167.305 1.00 92.39  ? 77  ASN N CA  1 
ATOM 7541 C C   . ASN E 5 77  ? 134.263 134.769 167.943 1.00 90.02  ? 77  ASN N C   1 
ATOM 7542 O O   . ASN E 5 77  ? 133.442 134.265 168.710 1.00 89.25  ? 77  ASN N O   1 
ATOM 7543 C CB  . ASN E 5 77  ? 135.494 132.574 168.001 1.00 97.32  ? 77  ASN N CB  1 
ATOM 7544 C CG  . ASN E 5 77  ? 135.799 131.450 167.036 1.00 97.84  ? 77  ASN N CG  1 
ATOM 7545 O OD1 . ASN E 5 77  ? 135.261 131.402 165.932 1.00 95.70  ? 77  ASN N OD1 1 
ATOM 7546 N ND2 . ASN E 5 77  ? 136.667 130.534 167.449 1.00 97.61  ? 77  ASN N ND2 1 
ATOM 7547 N N   . THR E 5 78  ? 134.246 136.061 167.630 1.00 92.46  ? 78  THR N N   1 
ATOM 7548 C CA  . THR E 5 78  ? 133.328 136.999 168.261 1.00 95.26  ? 78  THR N CA  1 
ATOM 7549 C C   . THR E 5 78  ? 132.711 137.906 167.209 1.00 96.88  ? 78  THR N C   1 
ATOM 7550 O O   . THR E 5 78  ? 133.421 138.447 166.356 1.00 97.42  ? 78  THR N O   1 
ATOM 7551 C CB  . THR E 5 78  ? 134.052 137.842 169.320 1.00 98.78  ? 78  THR N CB  1 
ATOM 7552 O OG1 . THR E 5 78  ? 134.905 137.000 170.105 1.00 99.62  ? 78  THR N OG1 1 
ATOM 7553 C CG2 . THR E 5 78  ? 133.056 138.540 170.232 1.00 98.18  ? 78  THR N CG2 1 
ATOM 7554 N N   . LEU E 5 79  ? 131.392 138.066 167.273 1.00 95.71  ? 79  LEU N N   1 
ATOM 7555 C CA  . LEU E 5 79  ? 130.665 139.041 166.475 1.00 93.61  ? 79  LEU N CA  1 
ATOM 7556 C C   . LEU E 5 79  ? 129.756 139.826 167.406 1.00 93.26  ? 79  LEU N C   1 
ATOM 7557 O O   . LEU E 5 79  ? 129.124 139.248 168.292 1.00 92.90  ? 79  LEU N O   1 
ATOM 7558 C CB  . LEU E 5 79  ? 129.884 138.351 165.331 1.00 90.07  ? 79  LEU N CB  1 
ATOM 7559 C CG  . LEU E 5 79  ? 128.859 139.080 164.453 1.00 90.23  ? 79  LEU N CG  1 
ATOM 7560 C CD1 . LEU E 5 79  ? 128.835 138.478 163.064 1.00 87.24  ? 79  LEU N CD1 1 
ATOM 7561 C CD2 . LEU E 5 79  ? 127.463 138.948 165.035 1.00 85.35  ? 79  LEU N CD2 1 
ATOM 7562 N N   . TYR E 5 80  ? 129.700 141.144 167.217 1.00 94.70  ? 80  TYR N N   1 
ATOM 7563 C CA  . TYR E 5 80  ? 129.010 142.003 168.167 1.00 96.48  ? 80  TYR N CA  1 
ATOM 7564 C C   . TYR E 5 80  ? 128.255 143.116 167.453 1.00 88.82  ? 80  TYR N C   1 
ATOM 7565 O O   . TYR E 5 80  ? 128.517 143.435 166.292 1.00 85.65  ? 80  TYR N O   1 
ATOM 7566 C CB  . TYR E 5 80  ? 129.984 142.609 169.191 1.00 100.31 ? 80  TYR N CB  1 
ATOM 7567 C CG  . TYR E 5 80  ? 131.393 142.808 168.678 1.00 97.69  ? 80  TYR N CG  1 
ATOM 7568 C CD1 . TYR E 5 80  ? 131.674 143.770 167.716 1.00 96.69  ? 80  TYR N CD1 1 
ATOM 7569 C CD2 . TYR E 5 80  ? 132.444 142.044 169.171 1.00 93.27  ? 80  TYR N CD2 1 
ATOM 7570 C CE1 . TYR E 5 80  ? 132.962 143.955 167.250 1.00 97.25  ? 80  TYR N CE1 1 
ATOM 7571 C CE2 . TYR E 5 80  ? 133.732 142.223 168.714 1.00 93.02  ? 80  TYR N CE2 1 
ATOM 7572 C CZ  . TYR E 5 80  ? 133.986 143.179 167.753 1.00 97.51  ? 80  TYR N CZ  1 
ATOM 7573 O OH  . TYR E 5 80  ? 135.270 143.361 167.294 1.00 102.14 ? 80  TYR N OH  1 
ATOM 7574 N N   . LEU E 5 81  ? 127.300 143.692 168.177 1.00 87.91  ? 81  LEU N N   1 
ATOM 7575 C CA  . LEU E 5 81  ? 126.549 144.867 167.764 1.00 87.86  ? 81  LEU N CA  1 
ATOM 7576 C C   . LEU E 5 81  ? 127.120 146.119 168.417 1.00 94.08  ? 81  LEU N C   1 
ATOM 7577 O O   . LEU E 5 81  ? 127.868 146.053 169.393 1.00 96.58  ? 81  LEU N O   1 
ATOM 7578 C CB  . LEU E 5 81  ? 125.074 144.735 168.145 1.00 92.82  ? 81  LEU N CB  1 
ATOM 7579 C CG  . LEU E 5 81  ? 124.044 144.225 167.142 1.00 94.34  ? 81  LEU N CG  1 
ATOM 7580 C CD1 . LEU E 5 81  ? 122.894 143.595 167.896 1.00 87.56  ? 81  LEU N CD1 1 
ATOM 7581 C CD2 . LEU E 5 81  ? 123.540 145.368 166.282 1.00 91.65  ? 81  LEU N CD2 1 
ATOM 7582 N N   . GLN E 5 82  ? 126.739 147.272 167.870 1.00 96.16  ? 82  GLN N N   1 
ATOM 7583 C CA  . GLN E 5 82  ? 127.087 148.567 168.444 1.00 98.50  ? 82  GLN N CA  1 
ATOM 7584 C C   . GLN E 5 82  ? 125.845 149.441 168.432 1.00 95.54  ? 82  GLN N C   1 
ATOM 7585 O O   . GLN E 5 82  ? 125.324 149.760 167.360 1.00 92.69  ? 82  GLN N O   1 
ATOM 7586 C CB  . GLN E 5 82  ? 128.222 149.242 167.667 1.00 99.64  ? 82  GLN N CB  1 
ATOM 7587 C CG  . GLN E 5 82  ? 129.594 148.632 167.902 1.00 103.90 ? 82  GLN N CG  1 
ATOM 7588 C CD  . GLN E 5 82  ? 130.667 149.259 167.033 1.00 110.33 ? 82  GLN N CD  1 
ATOM 7589 O OE1 . GLN E 5 82  ? 130.393 150.163 166.244 1.00 107.16 ? 82  GLN N OE1 1 
ATOM 7590 N NE2 . GLN E 5 82  ? 131.897 148.779 167.174 1.00 115.50 ? 82  GLN N NE2 1 
ATOM 7591 N N   . MET E 5 83  ? 125.375 149.831 169.610 1.00 97.45  ? 83  MET N N   1 
ATOM 7592 C CA  . MET E 5 83  ? 124.170 150.640 169.725 1.00 98.55  ? 83  MET N CA  1 
ATOM 7593 C C   . MET E 5 83  ? 124.553 152.112 169.824 1.00 102.99 ? 83  MET N C   1 
ATOM 7594 O O   . MET E 5 83  ? 125.263 152.513 170.751 1.00 108.32 ? 83  MET N O   1 
ATOM 7595 C CB  . MET E 5 83  ? 123.344 150.217 170.938 1.00 102.43 ? 83  MET N CB  1 
ATOM 7596 C CG  . MET E 5 83  ? 122.858 148.778 170.889 1.00 105.54 ? 83  MET N CG  1 
ATOM 7597 S SD  . MET E 5 83  ? 121.197 148.624 170.207 1.00 109.13 ? 83  MET N SD  1 
ATOM 7598 C CE  . MET E 5 83  ? 120.887 146.879 170.462 1.00 89.70  ? 83  MET N CE  1 
ATOM 7599 N N   . ASN E 5 84  ? 124.092 152.908 168.862 1.00 101.26 ? 84  ASN N N   1 
ATOM 7600 C CA  . ASN E 5 84  ? 124.259 154.352 168.888 1.00 102.16 ? 84  ASN N CA  1 
ATOM 7601 C C   . ASN E 5 84  ? 122.965 154.998 168.418 1.00 101.60 ? 84  ASN N C   1 
ATOM 7602 O O   . ASN E 5 84  ? 122.260 154.444 167.569 1.00 101.84 ? 84  ASN N O   1 
ATOM 7603 C CB  . ASN E 5 84  ? 125.426 154.817 168.005 1.00 104.70 ? 84  ASN N CB  1 
ATOM 7604 C CG  . ASN E 5 84  ? 126.744 154.173 168.389 1.00 109.45 ? 84  ASN N CG  1 
ATOM 7605 O OD1 . ASN E 5 84  ? 127.295 154.447 169.455 1.00 109.96 ? 84  ASN N OD1 1 
ATOM 7606 N ND2 . ASN E 5 84  ? 127.257 153.311 167.519 1.00 109.61 ? 84  ASN N ND2 1 
ATOM 7607 N N   . SER E 5 85  ? 122.682 156.185 168.967 1.00 105.79 ? 85  SER N N   1 
ATOM 7608 C CA  . SER E 5 85  ? 121.442 156.933 168.725 1.00 107.45 ? 85  SER N CA  1 
ATOM 7609 C C   . SER E 5 85  ? 120.218 156.064 169.006 1.00 101.63 ? 85  SER N C   1 
ATOM 7610 O O   . SER E 5 85  ? 119.284 155.973 168.207 1.00 99.49  ? 85  SER N O   1 
ATOM 7611 C CB  . SER E 5 85  ? 121.403 157.506 167.305 1.00 106.45 ? 85  SER N CB  1 
ATOM 7612 O OG  . SER E 5 85  ? 120.077 157.816 166.915 1.00 104.13 ? 85  SER N OG  1 
ATOM 7613 N N   . LEU E 5 86  ? 120.241 155.417 170.166 1.00 99.49  ? 86  LEU N N   1 
ATOM 7614 C CA  . LEU E 5 86  ? 119.294 154.353 170.463 1.00 100.03 ? 86  LEU N CA  1 
ATOM 7615 C C   . LEU E 5 86  ? 117.919 154.924 170.789 1.00 97.00  ? 86  LEU N C   1 
ATOM 7616 O O   . LEU E 5 86  ? 117.775 155.761 171.684 1.00 99.96  ? 86  LEU N O   1 
ATOM 7617 C CB  . LEU E 5 86  ? 119.828 153.510 171.617 1.00 104.95 ? 86  LEU N CB  1 
ATOM 7618 C CG  . LEU E 5 86  ? 119.027 152.342 172.179 1.00 105.27 ? 86  LEU N CG  1 
ATOM 7619 C CD1 . LEU E 5 86  ? 118.587 151.405 171.073 1.00 104.31 ? 86  LEU N CD1 1 
ATOM 7620 C CD2 . LEU E 5 86  ? 119.915 151.607 173.164 1.00 103.58 ? 86  LEU N CD2 1 
ATOM 7621 N N   . LYS E 5 87  ? 116.910 154.463 170.056 1.00 94.56  ? 87  LYS N N   1 
ATOM 7622 C CA  . LYS E 5 87  ? 115.505 154.824 170.054 1.00 98.03  ? 87  LYS N CA  1 
ATOM 7623 C C   . LYS E 5 87  ? 114.746 154.040 171.118 1.00 100.81 ? 87  LYS N C   1 
ATOM 7624 O O   . LYS E 5 87  ? 115.141 152.926 171.474 1.00 102.80 ? 87  LYS N O   1 
ATOM 7625 C CB  . LYS E 5 87  ? 114.888 154.552 168.678 1.00 100.23 ? 87  LYS N CB  1 
ATOM 7626 C CG  . LYS E 5 87  ? 115.239 155.591 167.625 1.00 102.27 ? 87  LYS N CG  1 
ATOM 7627 C CD  . LYS E 5 87  ? 114.230 155.588 166.487 1.00 104.60 ? 87  LYS N CD  1 
ATOM 7628 C CE  . LYS E 5 87  ? 114.276 154.283 165.710 1.00 101.09 ? 87  LYS N CE  1 
ATOM 7629 N NZ  . LYS E 5 87  ? 113.386 154.318 164.516 1.00 98.98  ? 87  LYS N NZ  1 
ATOM 7630 N N   . PRO E 5 88  ? 113.657 154.597 171.661 1.00 102.34 ? 88  PRO N N   1 
ATOM 7631 C CA  . PRO E 5 88  ? 112.889 153.858 172.675 1.00 100.93 ? 88  PRO N CA  1 
ATOM 7632 C C   . PRO E 5 88  ? 112.143 152.650 172.135 1.00 98.28  ? 88  PRO N C   1 
ATOM 7633 O O   . PRO E 5 88  ? 111.751 151.787 172.929 1.00 97.41  ? 88  PRO N O   1 
ATOM 7634 C CB  . PRO E 5 88  ? 111.917 154.914 173.220 1.00 102.28 ? 88  PRO N CB  1 
ATOM 7635 C CG  . PRO E 5 88  ? 111.798 155.914 172.132 1.00 101.39 ? 88  PRO N CG  1 
ATOM 7636 C CD  . PRO E 5 88  ? 113.148 155.969 171.485 1.00 102.02 ? 88  PRO N CD  1 
ATOM 7637 N N   . GLU E 5 89  ? 111.938 152.553 170.823 1.00 99.39  ? 89  GLU N N   1 
ATOM 7638 C CA  . GLU E 5 89  ? 111.186 151.459 170.224 1.00 98.04  ? 89  GLU N CA  1 
ATOM 7639 C C   . GLU E 5 89  ? 112.074 150.310 169.758 1.00 94.43  ? 89  GLU N C   1 
ATOM 7640 O O   . GLU E 5 89  ? 111.680 149.562 168.857 1.00 91.73  ? 89  GLU N O   1 
ATOM 7641 C CB  . GLU E 5 89  ? 110.345 151.982 169.057 1.00 104.61 ? 89  GLU N CB  1 
ATOM 7642 C CG  . GLU E 5 89  ? 111.150 152.689 167.976 1.00 109.03 ? 89  GLU N CG  1 
ATOM 7643 C CD  . GLU E 5 89  ? 110.588 152.461 166.587 1.00 114.30 ? 89  GLU N CD  1 
ATOM 7644 O OE1 . GLU E 5 89  ? 109.722 151.574 166.433 1.00 115.99 ? 89  GLU N OE1 1 
ATOM 7645 O OE2 . GLU E 5 89  ? 111.012 153.168 165.649 1.00 115.33 ? 89  GLU N OE2 1 
ATOM 7646 N N   . ASP E 5 90  ? 113.257 150.149 170.349 1.00 94.99  ? 90  ASP N N   1 
ATOM 7647 C CA  . ASP E 5 90  ? 114.181 149.088 169.974 1.00 93.14  ? 90  ASP N CA  1 
ATOM 7648 C C   . ASP E 5 90  ? 114.365 148.041 171.068 1.00 90.47  ? 90  ASP N C   1 
ATOM 7649 O O   . ASP E 5 90  ? 115.288 147.226 170.976 1.00 90.72  ? 90  ASP N O   1 
ATOM 7650 C CB  . ASP E 5 90  ? 115.540 149.679 169.593 1.00 96.49  ? 90  ASP N CB  1 
ATOM 7651 C CG  . ASP E 5 90  ? 115.452 150.658 168.438 1.00 99.24  ? 90  ASP N CG  1 
ATOM 7652 O OD1 . ASP E 5 90  ? 114.415 150.674 167.742 1.00 98.29  ? 90  ASP N OD1 1 
ATOM 7653 O OD2 . ASP E 5 90  ? 116.425 151.412 168.223 1.00 100.31 ? 90  ASP N OD2 1 
ATOM 7654 N N   . THR E 5 91  ? 113.521 148.039 172.096 1.00 88.01  ? 91  THR N N   1 
ATOM 7655 C CA  . THR E 5 91  ? 113.666 147.063 173.168 1.00 86.03  ? 91  THR N CA  1 
ATOM 7656 C C   . THR E 5 91  ? 113.184 145.686 172.719 1.00 86.41  ? 91  THR N C   1 
ATOM 7657 O O   . THR E 5 91  ? 112.071 145.537 172.202 1.00 88.49  ? 91  THR N O   1 
ATOM 7658 C CB  . THR E 5 91  ? 112.924 147.536 174.424 1.00 89.79  ? 91  THR N CB  1 
ATOM 7659 O OG1 . THR E 5 91  ? 112.962 146.514 175.429 1.00 92.19  ? 91  THR N OG1 1 
ATOM 7660 C CG2 . THR E 5 91  ? 111.482 147.968 174.133 1.00 89.92  ? 91  THR N CG2 1 
ATOM 7661 N N   . ALA E 5 92  ? 114.037 144.680 172.906 1.00 85.50  ? 92  ALA N N   1 
ATOM 7662 C CA  . ALA E 5 92  ? 113.797 143.339 172.384 1.00 84.00  ? 92  ALA N CA  1 
ATOM 7663 C C   . ALA E 5 92  ? 114.803 142.375 172.999 1.00 82.21  ? 92  ALA N C   1 
ATOM 7664 O O   . ALA E 5 92  ? 115.767 142.782 173.650 1.00 86.01  ? 92  ALA N O   1 
ATOM 7665 C CB  . ALA E 5 92  ? 113.902 143.302 170.859 1.00 82.72  ? 92  ALA N CB  1 
ATOM 7666 N N   . VAL E 5 93  ? 114.566 141.088 172.774 1.00 78.57  ? 93  VAL N N   1 
ATOM 7667 C CA  . VAL E 5 93  ? 115.525 140.036 173.086 1.00 80.06  ? 93  VAL N CA  1 
ATOM 7668 C C   . VAL E 5 93  ? 116.275 139.710 171.803 1.00 82.29  ? 93  VAL N C   1 
ATOM 7669 O O   . VAL E 5 93  ? 115.659 139.372 170.785 1.00 83.45  ? 93  VAL N O   1 
ATOM 7670 C CB  . VAL E 5 93  ? 114.830 138.790 173.654 1.00 83.67  ? 93  VAL N CB  1 
ATOM 7671 C CG1 . VAL E 5 93  ? 115.845 137.686 173.905 1.00 85.39  ? 93  VAL N CG1 1 
ATOM 7672 C CG2 . VAL E 5 93  ? 114.083 139.138 174.933 1.00 86.23  ? 93  VAL N CG2 1 
ATOM 7673 N N   . TYR E 5 94  ? 117.600 139.809 171.844 1.00 82.22  ? 94  TYR N N   1 
ATOM 7674 C CA  . TYR E 5 94  ? 118.420 139.741 170.642 1.00 79.80  ? 94  TYR N CA  1 
ATOM 7675 C C   . TYR E 5 94  ? 119.073 138.371 170.527 1.00 80.02  ? 94  TYR N C   1 
ATOM 7676 O O   . TYR E 5 94  ? 119.641 137.864 171.498 1.00 82.41  ? 94  TYR N O   1 
ATOM 7677 C CB  . TYR E 5 94  ? 119.481 140.841 170.647 1.00 77.77  ? 94  TYR N CB  1 
ATOM 7678 C CG  . TYR E 5 94  ? 118.976 142.175 170.143 1.00 76.77  ? 94  TYR N CG  1 
ATOM 7679 C CD1 . TYR E 5 94  ? 117.900 142.809 170.750 1.00 76.95  ? 94  TYR N CD1 1 
ATOM 7680 C CD2 . TYR E 5 94  ? 119.568 142.794 169.053 1.00 80.47  ? 94  TYR N CD2 1 
ATOM 7681 C CE1 . TYR E 5 94  ? 117.433 144.021 170.291 1.00 76.22  ? 94  TYR N CE1 1 
ATOM 7682 C CE2 . TYR E 5 94  ? 119.107 144.011 168.587 1.00 81.41  ? 94  TYR N CE2 1 
ATOM 7683 C CZ  . TYR E 5 94  ? 118.039 144.617 169.211 1.00 79.00  ? 94  TYR N CZ  1 
ATOM 7684 O OH  . TYR E 5 94  ? 117.575 145.827 168.755 1.00 85.83  ? 94  TYR N OH  1 
ATOM 7685 N N   . TYR E 5 95  ? 118.992 137.783 169.338 1.00 77.87  ? 95  TYR N N   1 
ATOM 7686 C CA  . TYR E 5 95  ? 119.492 136.444 169.077 1.00 77.13  ? 95  TYR N CA  1 
ATOM 7687 C C   . TYR E 5 95  ? 120.636 136.488 168.073 1.00 76.11  ? 95  TYR N C   1 
ATOM 7688 O O   . TYR E 5 95  ? 120.568 137.202 167.069 1.00 76.00  ? 95  TYR N O   1 
ATOM 7689 C CB  . TYR E 5 95  ? 118.379 135.536 168.549 1.00 79.08  ? 95  TYR N CB  1 
ATOM 7690 C CG  . TYR E 5 95  ? 117.167 135.426 169.448 1.00 82.50  ? 95  TYR N CG  1 
ATOM 7691 C CD1 . TYR E 5 95  ? 117.092 134.443 170.423 1.00 84.18  ? 95  TYR N CD1 1 
ATOM 7692 C CD2 . TYR E 5 95  ? 116.092 136.291 169.307 1.00 82.15  ? 95  TYR N CD2 1 
ATOM 7693 C CE1 . TYR E 5 95  ? 115.988 134.332 171.239 1.00 84.43  ? 95  TYR N CE1 1 
ATOM 7694 C CE2 . TYR E 5 95  ? 114.983 136.188 170.120 1.00 83.79  ? 95  TYR N CE2 1 
ATOM 7695 C CZ  . TYR E 5 95  ? 114.937 135.207 171.083 1.00 86.68  ? 95  TYR N CZ  1 
ATOM 7696 O OH  . TYR E 5 95  ? 113.834 135.099 171.897 1.00 90.47  ? 95  TYR N OH  1 
ATOM 7697 N N   . CYS E 5 96  ? 121.682 135.713 168.351 1.00 76.23  ? 96  CYS N N   1 
ATOM 7698 C CA  . CYS E 5 96  ? 122.855 135.622 167.482 1.00 75.29  ? 96  CYS N CA  1 
ATOM 7699 C C   . CYS E 5 96  ? 122.652 134.497 166.468 1.00 75.71  ? 96  CYS N C   1 
ATOM 7700 O O   . CYS E 5 96  ? 123.217 133.408 166.567 1.00 78.33  ? 96  CYS N O   1 
ATOM 7701 C CB  . CYS E 5 96  ? 124.106 135.398 168.318 1.00 84.37  ? 96  CYS N CB  1 
ATOM 7702 S SG  . CYS E 5 96  ? 125.607 136.159 167.696 1.00 111.58 ? 96  CYS N SG  1 
ATOM 7703 N N   . ALA E 5 97  ? 121.816 134.784 165.477 1.00 73.54  ? 97  ALA N N   1 
ATOM 7704 C CA  . ALA E 5 97  ? 121.422 133.767 164.516 1.00 71.60  ? 97  ALA N CA  1 
ATOM 7705 C C   . ALA E 5 97  ? 122.555 133.470 163.543 1.00 66.13  ? 97  ALA N C   1 
ATOM 7706 O O   . ALA E 5 97  ? 123.428 134.300 163.292 1.00 69.19  ? 97  ALA N O   1 
ATOM 7707 C CB  . ALA E 5 97  ? 120.180 134.206 163.749 1.00 72.99  ? 97  ALA N CB  1 
ATOM 7708 N N   . ARG E 5 98  ? 122.522 132.264 162.986 1.00 61.87  ? 98  ARG N N   1 
ATOM 7709 C CA  . ARG E 5 98  ? 123.585 131.759 162.132 1.00 62.94  ? 98  ARG N CA  1 
ATOM 7710 C C   . ARG E 5 98  ? 122.971 131.043 160.939 1.00 68.25  ? 98  ARG N C   1 
ATOM 7711 O O   . ARG E 5 98  ? 121.993 130.306 161.088 1.00 74.43  ? 98  ARG N O   1 
ATOM 7712 C CB  . ARG E 5 98  ? 124.507 130.822 162.923 1.00 69.11  ? 98  ARG N CB  1 
ATOM 7713 C CG  . ARG E 5 98  ? 125.221 129.765 162.112 1.00 72.04  ? 98  ARG N CG  1 
ATOM 7714 C CD  . ARG E 5 98  ? 125.875 128.745 163.016 1.00 74.72  ? 98  ARG N CD  1 
ATOM 7715 N NE  . ARG E 5 98  ? 126.603 127.731 162.268 1.00 74.97  ? 98  ARG N NE  1 
ATOM 7716 C CZ  . ARG E 5 98  ? 126.042 126.689 161.671 1.00 76.05  ? 98  ARG N CZ  1 
ATOM 7717 N NH1 . ARG E 5 98  ? 124.734 126.496 161.700 1.00 75.69  ? 98  ARG N NH1 1 
ATOM 7718 N NH2 . ARG E 5 98  ? 126.813 125.813 161.037 1.00 77.05  ? 98  ARG N NH2 1 
ATOM 7719 N N   . CYS E 5 99  ? 123.537 131.277 159.760 1.00 68.29  ? 99  CYS N N   1 
ATOM 7720 C CA  . CYS E 5 99  ? 123.016 130.673 158.544 1.00 71.36  ? 99  CYS N CA  1 
ATOM 7721 C C   . CYS E 5 99  ? 123.291 129.170 158.550 1.00 71.11  ? 99  CYS N C   1 
ATOM 7722 O O   . CYS E 5 99  ? 124.354 128.735 159.003 1.00 74.86  ? 99  CYS N O   1 
ATOM 7723 C CB  . CYS E 5 99  ? 123.661 131.320 157.324 1.00 79.71  ? 99  CYS N CB  1 
ATOM 7724 S SG  . CYS E 5 99  ? 122.583 131.499 155.906 1.00 103.95 ? 99  CYS N SG  1 
ATOM 7725 N N   . PRO E 5 100 ? 122.355 128.350 158.061 1.00 65.97  ? 100 PRO N N   1 
ATOM 7726 C CA  . PRO E 5 100 ? 122.512 126.896 158.199 1.00 70.04  ? 100 PRO N CA  1 
ATOM 7727 C C   . PRO E 5 100 ? 123.491 126.267 157.225 1.00 70.14  ? 100 PRO N C   1 
ATOM 7728 O O   . PRO E 5 100 ? 123.785 125.075 157.372 1.00 74.14  ? 100 PRO N O   1 
ATOM 7729 C CB  . PRO E 5 100 ? 121.094 126.375 157.952 1.00 70.45  ? 100 PRO N CB  1 
ATOM 7730 C CG  . PRO E 5 100 ? 120.509 127.377 157.040 1.00 64.83  ? 100 PRO N CG  1 
ATOM 7731 C CD  . PRO E 5 100 ? 121.041 128.697 157.499 1.00 64.58  ? 100 PRO N CD  1 
ATOM 7732 N N   . ALA E 5 101 ? 124.007 127.000 156.248 1.00 70.51  ? 101 ALA N N   1 
ATOM 7733 C CA  . ALA E 5 101 ? 124.823 126.359 155.232 1.00 71.21  ? 101 ALA N CA  1 
ATOM 7734 C C   . ALA E 5 101 ? 126.177 127.038 155.107 1.00 72.96  ? 101 ALA N C   1 
ATOM 7735 O O   . ALA E 5 101 ? 126.293 128.252 155.304 1.00 77.48  ? 101 ALA N O   1 
ATOM 7736 C CB  . ALA E 5 101 ? 124.116 126.378 153.869 1.00 73.65  ? 101 ALA N CB  1 
ATOM 7737 N N   . PRO E 5 102 ? 127.221 126.273 154.793 1.00 70.32  ? 102 PRO N N   1 
ATOM 7738 C CA  . PRO E 5 102 ? 128.525 126.880 154.512 1.00 73.17  ? 102 PRO N CA  1 
ATOM 7739 C C   . PRO E 5 102 ? 128.489 127.664 153.214 1.00 75.51  ? 102 PRO N C   1 
ATOM 7740 O O   . PRO E 5 102 ? 127.956 127.187 152.210 1.00 77.43  ? 102 PRO N O   1 
ATOM 7741 C CB  . PRO E 5 102 ? 129.453 125.671 154.378 1.00 74.78  ? 102 PRO N CB  1 
ATOM 7742 C CG  . PRO E 5 102 ? 128.794 124.612 155.142 1.00 75.49  ? 102 PRO N CG  1 
ATOM 7743 C CD  . PRO E 5 102 ? 127.325 124.814 154.938 1.00 72.00  ? 102 PRO N CD  1 
ATOM 7744 N N   . PHE E 5 103 ? 129.075 128.871 153.258 1.00 75.89  ? 103 PHE N N   1 
ATOM 7745 C CA  . PHE E 5 103 ? 129.360 129.797 152.154 1.00 77.47  ? 103 PHE N CA  1 
ATOM 7746 C C   . PHE E 5 103 ? 128.333 129.805 151.027 1.00 78.43  ? 103 PHE N C   1 
ATOM 7747 O O   . PHE E 5 103 ? 128.692 129.724 149.848 1.00 81.79  ? 103 PHE N O   1 
ATOM 7748 C CB  . PHE E 5 103 ? 130.762 129.557 151.572 1.00 78.16  ? 103 PHE N CB  1 
ATOM 7749 C CG  . PHE E 5 103 ? 131.199 128.130 151.578 1.00 79.47  ? 103 PHE N CG  1 
ATOM 7750 C CD1 . PHE E 5 103 ? 130.677 127.231 150.672 1.00 81.15  ? 103 PHE N CD1 1 
ATOM 7751 C CD2 . PHE E 5 103 ? 132.127 127.684 152.501 1.00 79.44  ? 103 PHE N CD2 1 
ATOM 7752 C CE1 . PHE E 5 103 ? 131.070 125.919 150.688 1.00 82.86  ? 103 PHE N CE1 1 
ATOM 7753 C CE2 . PHE E 5 103 ? 132.532 126.369 152.519 1.00 77.57  ? 103 PHE N CE2 1 
ATOM 7754 C CZ  . PHE E 5 103 ? 132.003 125.483 151.612 1.00 80.94  ? 103 PHE N CZ  1 
ATOM 7755 N N   . THR E 5 104 ? 127.057 129.888 151.383 1.00 76.74  ? 104 THR N N   1 
ATOM 7756 C CA  . THR E 5 104 ? 125.984 130.113 150.430 1.00 77.92  ? 104 THR N CA  1 
ATOM 7757 C C   . THR E 5 104 ? 125.434 131.512 150.647 1.00 78.33  ? 104 THR N C   1 
ATOM 7758 O O   . THR E 5 104 ? 125.268 131.949 151.790 1.00 79.96  ? 104 THR N O   1 
ATOM 7759 C CB  . THR E 5 104 ? 124.866 129.081 150.587 1.00 83.82  ? 104 THR N CB  1 
ATOM 7760 O OG1 . THR E 5 104 ? 124.402 129.080 151.943 1.00 86.44  ? 104 THR N OG1 1 
ATOM 7761 C CG2 . THR E 5 104 ? 125.361 127.691 150.217 1.00 82.71  ? 104 THR N CG2 1 
ATOM 7762 N N   . ARG E 5 105 ? 125.180 132.221 149.547 1.00 80.09  ? 105 ARG N N   1 
ATOM 7763 C CA  . ARG E 5 105 ? 124.700 133.596 149.648 1.00 82.94  ? 105 ARG N CA  1 
ATOM 7764 C C   . ARG E 5 105 ? 123.303 133.654 150.250 1.00 86.30  ? 105 ARG N C   1 
ATOM 7765 O O   . ARG E 5 105 ? 123.001 134.554 151.042 1.00 88.14  ? 105 ARG N O   1 
ATOM 7766 C CB  . ARG E 5 105 ? 124.723 134.261 148.272 1.00 84.08  ? 105 ARG N CB  1 
ATOM 7767 N N   . ASP E 5 106 ? 122.441 132.708 149.888 1.00 86.55  ? 106 ASP N N   1 
ATOM 7768 C CA  . ASP E 5 106 ? 121.095 132.673 150.434 1.00 85.84  ? 106 ASP N CA  1 
ATOM 7769 C C   . ASP E 5 106 ? 121.123 132.253 151.896 1.00 81.22  ? 106 ASP N C   1 
ATOM 7770 O O   . ASP E 5 106 ? 121.987 131.489 152.333 1.00 79.87  ? 106 ASP N O   1 
ATOM 7771 C CB  . ASP E 5 106 ? 120.213 131.714 149.634 1.00 89.18  ? 106 ASP N CB  1 
ATOM 7772 C CG  . ASP E 5 106 ? 120.588 130.260 149.849 1.00 88.88  ? 106 ASP N CG  1 
ATOM 7773 O OD1 . ASP E 5 106 ? 121.760 129.905 149.607 1.00 90.39  ? 106 ASP N OD1 1 
ATOM 7774 O OD2 . ASP E 5 106 ? 119.709 129.473 150.259 1.00 85.69  ? 106 ASP N OD2 1 
ATOM 7775 N N   . CYS E 5 107 ? 120.170 132.772 152.661 1.00 80.43  ? 107 CYS N N   1 
ATOM 7776 C CA  . CYS E 5 107 ? 120.063 132.440 154.070 1.00 80.24  ? 107 CYS N CA  1 
ATOM 7777 C C   . CYS E 5 107 ? 118.592 132.233 154.394 1.00 80.60  ? 107 CYS N C   1 
ATOM 7778 O O   . CYS E 5 107 ? 117.764 133.108 154.121 1.00 83.73  ? 107 CYS N O   1 
ATOM 7779 C CB  . CYS E 5 107 ? 120.666 133.541 154.935 1.00 81.85  ? 107 CYS N CB  1 
ATOM 7780 S SG  . CYS E 5 107 ? 121.258 132.918 156.496 1.00 103.77 ? 107 CYS N SG  1 
ATOM 7781 N N   . PHE E 5 108 ? 118.271 131.084 154.974 1.00 76.40  ? 108 PHE N N   1 
ATOM 7782 C CA  . PHE E 5 108 ? 116.902 130.610 155.096 1.00 74.71  ? 108 PHE N CA  1 
ATOM 7783 C C   . PHE E 5 108 ? 116.520 130.404 156.555 1.00 76.85  ? 108 PHE N C   1 
ATOM 7784 O O   . PHE E 5 108 ? 117.331 129.929 157.357 1.00 81.16  ? 108 PHE N O   1 
ATOM 7785 C CB  . PHE E 5 108 ? 116.727 129.297 154.338 1.00 77.23  ? 108 PHE N CB  1 
ATOM 7786 C CG  . PHE E 5 108 ? 116.045 129.437 153.010 1.00 74.10  ? 108 PHE N CG  1 
ATOM 7787 C CD1 . PHE E 5 108 ? 114.798 130.029 152.915 1.00 75.95  ? 108 PHE N CD1 1 
ATOM 7788 C CD2 . PHE E 5 108 ? 116.643 128.957 151.859 1.00 71.95  ? 108 PHE N CD2 1 
ATOM 7789 C CE1 . PHE E 5 108 ? 114.166 130.141 151.698 1.00 74.96  ? 108 PHE N CE1 1 
ATOM 7790 C CE2 . PHE E 5 108 ? 116.019 129.069 150.640 1.00 72.62  ? 108 PHE N CE2 1 
ATOM 7791 C CZ  . PHE E 5 108 ? 114.779 129.664 150.558 1.00 73.12  ? 108 PHE N CZ  1 
ATOM 7792 N N   . ASP E 5 109 ? 115.273 130.766 156.876 1.00 74.40  ? 109 ASP N N   1 
ATOM 7793 C CA  . ASP E 5 109 ? 114.628 130.503 158.169 1.00 77.68  ? 109 ASP N CA  1 
ATOM 7794 C C   . ASP E 5 109 ? 115.401 131.097 159.342 1.00 79.28  ? 109 ASP N C   1 
ATOM 7795 O O   . ASP E 5 109 ? 115.491 130.498 160.416 1.00 82.53  ? 109 ASP N O   1 
ATOM 7796 C CB  . ASP E 5 109 ? 114.399 129.010 158.392 1.00 85.10  ? 109 ASP N CB  1 
ATOM 7797 C CG  . ASP E 5 109 ? 113.909 128.308 157.155 1.00 93.04  ? 109 ASP N CG  1 
ATOM 7798 O OD1 . ASP E 5 109 ? 112.962 128.807 156.512 1.00 92.41  ? 109 ASP N OD1 1 
ATOM 7799 O OD2 . ASP E 5 109 ? 114.447 127.230 156.851 1.00 95.53  ? 109 ASP N OD2 1 
ATOM 7800 N N   . VAL E 5 110 ? 115.969 132.279 159.136 1.00 76.83  ? 110 VAL N N   1 
ATOM 7801 C CA  . VAL E 5 110 ? 116.598 132.988 160.241 1.00 73.55  ? 110 VAL N CA  1 
ATOM 7802 C C   . VAL E 5 110 ? 115.538 133.504 161.203 1.00 75.76  ? 110 VAL N C   1 
ATOM 7803 O O   . VAL E 5 110 ? 115.709 133.456 162.427 1.00 76.71  ? 110 VAL N O   1 
ATOM 7804 C CB  . VAL E 5 110 ? 117.485 134.112 159.686 1.00 70.33  ? 110 VAL N CB  1 
ATOM 7805 C CG1 . VAL E 5 110 ? 118.121 134.905 160.799 1.00 68.69  ? 110 VAL N CG1 1 
ATOM 7806 C CG2 . VAL E 5 110 ? 118.535 133.521 158.788 1.00 73.00  ? 110 VAL N CG2 1 
ATOM 7807 N N   . THR E 5 111 ? 114.413 133.973 160.668 1.00 76.86  ? 111 THR N N   1 
ATOM 7808 C CA  . THR E 5 111 ? 113.331 134.537 161.457 1.00 78.00  ? 111 THR N CA  1 
ATOM 7809 C C   . THR E 5 111 ? 112.227 133.527 161.743 1.00 78.52  ? 111 THR N C   1 
ATOM 7810 O O   . THR E 5 111 ? 111.084 133.923 161.991 1.00 80.22  ? 111 THR N O   1 
ATOM 7811 C CB  . THR E 5 111 ? 112.749 135.760 160.749 1.00 81.11  ? 111 THR N CB  1 
ATOM 7812 O OG1 . THR E 5 111 ? 112.020 135.340 159.591 1.00 85.05  ? 111 THR N OG1 1 
ATOM 7813 C CG2 . THR E 5 111 ? 113.861 136.704 160.322 1.00 80.18  ? 111 THR N CG2 1 
ATOM 7814 N N   . SER E 5 112 ? 112.540 132.236 161.704 1.00 77.28  ? 112 SER N N   1 
ATOM 7815 C CA  . SER E 5 112 ? 111.545 131.215 161.995 1.00 78.42  ? 112 SER N CA  1 
ATOM 7816 C C   . SER E 5 112 ? 111.204 131.207 163.480 1.00 80.96  ? 112 SER N C   1 
ATOM 7817 O O   . SER E 5 112 ? 112.019 131.575 164.329 1.00 82.11  ? 112 SER N O   1 
ATOM 7818 C CB  . SER E 5 112 ? 112.051 129.839 161.570 1.00 79.32  ? 112 SER N CB  1 
ATOM 7819 O OG  . SER E 5 112 ? 111.555 128.831 162.433 1.00 85.03  ? 112 SER N OG  1 
ATOM 7820 N N   . THR E 5 113 ? 109.976 130.784 163.789 1.00 81.04  ? 113 THR N N   1 
ATOM 7821 C CA  . THR E 5 113 ? 109.533 130.752 165.178 1.00 81.26  ? 113 THR N CA  1 
ATOM 7822 C C   . THR E 5 113 ? 110.190 129.631 165.967 1.00 79.72  ? 113 THR N C   1 
ATOM 7823 O O   . THR E 5 113 ? 110.202 129.684 167.201 1.00 78.98  ? 113 THR N O   1 
ATOM 7824 C CB  . THR E 5 113 ? 108.011 130.624 165.253 1.00 85.06  ? 113 THR N CB  1 
ATOM 7825 O OG1 . THR E 5 113 ? 107.600 130.625 166.625 1.00 90.62  ? 113 THR N OG1 1 
ATOM 7826 C CG2 . THR E 5 113 ? 107.536 129.344 164.580 1.00 82.37  ? 113 THR N CG2 1 
ATOM 7827 N N   . THR E 5 114 ? 110.727 128.622 165.290 1.00 79.27  ? 114 THR N N   1 
ATOM 7828 C CA  . THR E 5 114 ? 111.559 127.606 165.912 1.00 76.70  ? 114 THR N CA  1 
ATOM 7829 C C   . THR E 5 114 ? 112.801 127.406 165.057 1.00 76.50  ? 114 THR N C   1 
ATOM 7830 O O   . THR E 5 114 ? 112.726 127.393 163.825 1.00 79.23  ? 114 THR N O   1 
ATOM 7831 C CB  . THR E 5 114 ? 110.800 126.280 166.108 1.00 80.44  ? 114 THR N CB  1 
ATOM 7832 O OG1 . THR E 5 114 ? 111.706 125.267 166.561 1.00 84.81  ? 114 THR N OG1 1 
ATOM 7833 C CG2 . THR E 5 114 ? 110.106 125.828 164.824 1.00 75.86  ? 114 THR N CG2 1 
ATOM 7834 N N   . TYR E 5 115 ? 113.948 127.287 165.714 1.00 75.01  ? 115 TYR N N   1 
ATOM 7835 C CA  . TYR E 5 115 ? 115.216 127.224 165.009 1.00 72.92  ? 115 TYR N CA  1 
ATOM 7836 C C   . TYR E 5 115 ? 116.214 126.467 165.867 1.00 75.25  ? 115 TYR N C   1 
ATOM 7837 O O   . TYR E 5 115 ? 116.051 126.346 167.084 1.00 80.39  ? 115 TYR N O   1 
ATOM 7838 C CB  . TYR E 5 115 ? 115.731 128.627 164.683 1.00 73.30  ? 115 TYR N CB  1 
ATOM 7839 C CG  . TYR E 5 115 ? 116.634 128.699 163.479 1.00 72.17  ? 115 TYR N CG  1 
ATOM 7840 C CD1 . TYR E 5 115 ? 116.579 127.738 162.486 1.00 73.30  ? 115 TYR N CD1 1 
ATOM 7841 C CD2 . TYR E 5 115 ? 117.534 129.743 163.333 1.00 73.63  ? 115 TYR N CD2 1 
ATOM 7842 C CE1 . TYR E 5 115 ? 117.404 127.809 161.384 1.00 75.17  ? 115 TYR N CE1 1 
ATOM 7843 C CE2 . TYR E 5 115 ? 118.359 129.822 162.239 1.00 73.97  ? 115 TYR N CE2 1 
ATOM 7844 C CZ  . TYR E 5 115 ? 118.290 128.855 161.269 1.00 75.21  ? 115 TYR N CZ  1 
ATOM 7845 O OH  . TYR E 5 115 ? 119.116 128.935 160.176 1.00 78.35  ? 115 TYR N OH  1 
ATOM 7846 N N   . ALA E 5 116 ? 117.256 125.956 165.218 1.00 73.47  ? 116 ALA N N   1 
ATOM 7847 C CA  . ALA E 5 116 ? 118.286 125.189 165.903 1.00 77.27  ? 116 ALA N CA  1 
ATOM 7848 C C   . ALA E 5 116 ? 119.549 126.001 166.156 1.00 77.94  ? 116 ALA N C   1 
ATOM 7849 O O   . ALA E 5 116 ? 120.013 126.093 167.296 1.00 78.82  ? 116 ALA N O   1 
ATOM 7850 C CB  . ALA E 5 116 ? 118.627 123.933 165.095 1.00 75.40  ? 116 ALA N CB  1 
ATOM 7851 N N   . TYR E 5 117 ? 120.114 126.598 165.108 1.00 76.20  ? 117 TYR N N   1 
ATOM 7852 C CA  . TYR E 5 117 ? 121.355 127.359 165.219 1.00 73.19  ? 117 TYR N CA  1 
ATOM 7853 C C   . TYR E 5 117 ? 121.002 128.802 165.566 1.00 74.21  ? 117 TYR N C   1 
ATOM 7854 O O   . TYR E 5 117 ? 121.079 129.717 164.745 1.00 75.99  ? 117 TYR N O   1 
ATOM 7855 C CB  . TYR E 5 117 ? 122.153 127.258 163.928 1.00 73.69  ? 117 TYR N CB  1 
ATOM 7856 C CG  . TYR E 5 117 ? 122.006 125.921 163.243 1.00 73.40  ? 117 TYR N CG  1 
ATOM 7857 C CD1 . TYR E 5 117 ? 122.485 124.761 163.833 1.00 77.05  ? 117 TYR N CD1 1 
ATOM 7858 C CD2 . TYR E 5 117 ? 121.373 125.818 162.015 1.00 70.95  ? 117 TYR N CD2 1 
ATOM 7859 C CE1 . TYR E 5 117 ? 122.346 123.539 163.212 1.00 80.95  ? 117 TYR N CE1 1 
ATOM 7860 C CE2 . TYR E 5 117 ? 121.229 124.602 161.387 1.00 75.73  ? 117 TYR N CE2 1 
ATOM 7861 C CZ  . TYR E 5 117 ? 121.716 123.467 161.989 1.00 82.73  ? 117 TYR N CZ  1 
ATOM 7862 O OH  . TYR E 5 117 ? 121.572 122.251 161.364 1.00 84.66  ? 117 TYR N OH  1 
ATOM 7863 N N   . ARG E 5 118 ? 120.600 128.996 166.818 1.00 72.37  ? 118 ARG N N   1 
ATOM 7864 C CA  . ARG E 5 118 ? 120.237 130.312 167.316 1.00 74.00  ? 118 ARG N CA  1 
ATOM 7865 C C   . ARG E 5 118 ? 120.578 130.375 168.795 1.00 79.59  ? 118 ARG N C   1 
ATOM 7866 O O   . ARG E 5 118 ? 120.492 129.372 169.508 1.00 84.44  ? 118 ARG N O   1 
ATOM 7867 C CB  . ARG E 5 118 ? 118.750 130.602 167.086 1.00 73.46  ? 118 ARG N CB  1 
ATOM 7868 C CG  . ARG E 5 118 ? 118.359 132.059 167.228 1.00 75.24  ? 118 ARG N CG  1 
ATOM 7869 C CD  . ARG E 5 118 ? 116.861 132.209 167.394 1.00 74.91  ? 118 ARG N CD  1 
ATOM 7870 N NE  . ARG E 5 118 ? 116.179 132.249 166.107 1.00 79.88  ? 118 ARG N NE  1 
ATOM 7871 C CZ  . ARG E 5 118 ? 114.879 132.058 165.943 1.00 81.88  ? 118 ARG N CZ  1 
ATOM 7872 N NH1 . ARG E 5 118 ? 114.081 131.811 166.968 1.00 80.87  ? 118 ARG N NH1 1 
ATOM 7873 N NH2 . ARG E 5 118 ? 114.365 132.116 164.718 1.00 83.37  ? 118 ARG N NH2 1 
ATOM 7874 N N   . GLY E 5 119 ? 120.972 131.557 169.249 1.00 79.51  ? 119 GLY N N   1 
ATOM 7875 C CA  . GLY E 5 119 ? 121.336 131.734 170.637 1.00 83.94  ? 119 GLY N CA  1 
ATOM 7876 C C   . GLY E 5 119 ? 120.129 131.760 171.552 1.00 90.01  ? 119 GLY N C   1 
ATOM 7877 O O   . GLY E 5 119 ? 118.976 131.829 171.125 1.00 92.41  ? 119 GLY N O   1 
ATOM 7878 N N   . GLN E 5 120 ? 120.415 131.687 172.855 1.00 92.11  ? 120 GLN N N   1 
ATOM 7879 C CA  . GLN E 5 120 ? 119.357 131.754 173.858 1.00 94.34  ? 120 GLN N CA  1 
ATOM 7880 C C   . GLN E 5 120 ? 118.718 133.137 173.888 1.00 97.71  ? 120 GLN N C   1 
ATOM 7881 O O   . GLN E 5 120 ? 117.488 133.264 173.901 1.00 100.85 ? 120 GLN N O   1 
ATOM 7882 C CB  . GLN E 5 120 ? 119.917 131.382 175.231 1.00 96.59  ? 120 GLN N CB  1 
ATOM 7883 C CG  . GLN E 5 120 ? 119.052 131.819 176.401 1.00 103.16 ? 120 GLN N CG  1 
ATOM 7884 C CD  . GLN E 5 120 ? 119.762 131.688 177.733 1.00 112.37 ? 120 GLN N CD  1 
ATOM 7885 O OE1 . GLN E 5 120 ? 120.781 131.006 177.843 1.00 114.98 ? 120 GLN N OE1 1 
ATOM 7886 N NE2 . GLN E 5 120 ? 119.225 132.343 178.756 1.00 114.76 ? 120 GLN N NE2 1 
ATOM 7887 N N   . GLY E 5 121 ? 119.535 134.187 173.887 1.00 94.50  ? 121 GLY N N   1 
ATOM 7888 C CA  . GLY E 5 121 ? 119.016 135.538 173.804 1.00 90.10  ? 121 GLY N CA  1 
ATOM 7889 C C   . GLY E 5 121 ? 119.296 136.406 175.012 1.00 91.16  ? 121 GLY N C   1 
ATOM 7890 O O   . GLY E 5 121 ? 119.140 135.965 176.154 1.00 93.45  ? 121 GLY N O   1 
ATOM 7891 N N   . THR E 5 122 ? 119.708 137.648 174.770 1.00 91.37  ? 122 THR N N   1 
ATOM 7892 C CA  . THR E 5 122 ? 119.906 138.640 175.817 1.00 90.64  ? 122 THR N CA  1 
ATOM 7893 C C   . THR E 5 122 ? 118.897 139.765 175.643 1.00 89.64  ? 122 THR N C   1 
ATOM 7894 O O   . THR E 5 122 ? 118.677 140.240 174.525 1.00 87.69  ? 122 THR N O   1 
ATOM 7895 C CB  . THR E 5 122 ? 121.327 139.201 175.796 1.00 92.10  ? 122 THR N CB  1 
ATOM 7896 O OG1 . THR E 5 122 ? 121.584 139.816 174.527 1.00 89.42  ? 122 THR N OG1 1 
ATOM 7897 C CG2 . THR E 5 122 ? 122.338 138.101 176.049 1.00 94.11  ? 122 THR N CG2 1 
ATOM 7898 N N   . GLN E 5 123 ? 118.292 140.184 176.747 1.00 88.37  ? 123 GLN N N   1 
ATOM 7899 C CA  . GLN E 5 123 ? 117.228 141.176 176.729 1.00 84.92  ? 123 GLN N CA  1 
ATOM 7900 C C   . GLN E 5 123 ? 117.809 142.569 176.922 1.00 84.41  ? 123 GLN N C   1 
ATOM 7901 O O   . GLN E 5 123 ? 118.578 142.801 177.859 1.00 86.56  ? 123 GLN N O   1 
ATOM 7902 C CB  . GLN E 5 123 ? 116.210 140.869 177.827 1.00 83.40  ? 123 GLN N CB  1 
ATOM 7903 C CG  . GLN E 5 123 ? 115.258 142.003 178.160 1.00 82.44  ? 123 GLN N CG  1 
ATOM 7904 C CD  . GLN E 5 123 ? 114.149 142.157 177.144 1.00 83.55  ? 123 GLN N CD  1 
ATOM 7905 O OE1 . GLN E 5 123 ? 114.316 142.818 176.123 1.00 84.56  ? 123 GLN N OE1 1 
ATOM 7906 N NE2 . GLN E 5 123 ? 113.006 141.543 177.419 1.00 83.26  ? 123 GLN N NE2 1 
ATOM 7907 N N   . VAL E 5 124 ? 117.444 143.491 176.036 1.00 82.18  ? 124 VAL N N   1 
ATOM 7908 C CA  . VAL E 5 124 ? 117.791 144.898 176.185 1.00 84.19  ? 124 VAL N CA  1 
ATOM 7909 C C   . VAL E 5 124 ? 116.502 145.687 176.384 1.00 88.13  ? 124 VAL N C   1 
ATOM 7910 O O   . VAL E 5 124 ? 115.521 145.492 175.656 1.00 91.76  ? 124 VAL N O   1 
ATOM 7911 C CB  . VAL E 5 124 ? 118.621 145.427 174.996 1.00 84.60  ? 124 VAL N CB  1 
ATOM 7912 C CG1 . VAL E 5 124 ? 119.975 144.750 174.971 1.00 89.53  ? 124 VAL N CG1 1 
ATOM 7913 C CG2 . VAL E 5 124 ? 117.936 145.208 173.659 1.00 82.70  ? 124 VAL N CG2 1 
ATOM 7914 N N   . THR E 5 125 ? 116.480 146.517 177.422 1.00 90.25  ? 125 THR N N   1 
ATOM 7915 C CA  . THR E 5 125 ? 115.323 147.334 177.756 1.00 90.89  ? 125 THR N CA  1 
ATOM 7916 C C   . THR E 5 125 ? 115.734 148.795 177.730 1.00 94.78  ? 125 THR N C   1 
ATOM 7917 O O   . THR E 5 125 ? 116.711 149.179 178.378 1.00 98.05  ? 125 THR N O   1 
ATOM 7918 C CB  . THR E 5 125 ? 114.756 146.990 179.137 1.00 95.02  ? 125 THR N CB  1 
ATOM 7919 O OG1 . THR E 5 125 ? 115.523 147.659 180.146 1.00 99.30  ? 125 THR N OG1 1 
ATOM 7920 C CG2 . THR E 5 125 ? 114.783 145.489 179.394 1.00 92.53  ? 125 THR N CG2 1 
ATOM 7921 N N   . VAL E 5 126 ? 114.994 149.604 176.981 1.00 100.21 ? 126 VAL N N   1 
ATOM 7922 C CA  . VAL E 5 126 ? 115.230 151.040 176.915 1.00 109.89 ? 126 VAL N CA  1 
ATOM 7923 C C   . VAL E 5 126 ? 113.964 151.764 177.365 1.00 117.62 ? 126 VAL N C   1 
ATOM 7924 O O   . VAL E 5 126 ? 112.850 151.400 176.964 1.00 117.97 ? 126 VAL N O   1 
ATOM 7925 C CB  . VAL E 5 126 ? 115.704 151.490 175.517 1.00 106.78 ? 126 VAL N CB  1 
ATOM 7926 C CG1 . VAL E 5 126 ? 116.963 150.742 175.144 1.00 105.54 ? 126 VAL N CG1 1 
ATOM 7927 C CG2 . VAL E 5 126 ? 114.679 151.187 174.441 1.00 101.25 ? 126 VAL N CG2 1 
ATOM 7928 N N   . SER E 5 127 ? 114.132 152.730 178.266 1.00 119.83 ? 127 SER N N   1 
ATOM 7929 C CA  . SER E 5 127 ? 113.028 153.499 178.823 1.00 126.09 ? 127 SER N CA  1 
ATOM 7930 C C   . SER E 5 127 ? 113.594 154.752 179.472 1.00 125.87 ? 127 SER N C   1 
ATOM 7931 O O   . SER E 5 127 ? 114.799 154.855 179.716 1.00 120.02 ? 127 SER N O   1 
ATOM 7932 C CB  . SER E 5 127 ? 112.221 152.688 179.845 1.00 126.83 ? 127 SER N CB  1 
ATOM 7933 O OG  . SER E 5 127 ? 111.129 153.441 180.344 1.00 127.42 ? 127 SER N OG  1 
ATOM 7934 N N   . SER E 5 128 ? 112.707 155.699 179.754 1.00 129.57 ? 128 SER N N   1 
ATOM 7935 C CA  . SER E 5 128 ? 113.101 156.938 180.414 1.00 128.97 ? 128 SER N CA  1 
ATOM 7936 C C   . SER E 5 128 ? 113.142 156.759 181.928 1.00 130.06 ? 128 SER N C   1 
ATOM 7937 O O   . SER E 5 128 ? 113.766 155.827 182.437 1.00 129.73 ? 128 SER N O   1 
ATOM 7938 C CB  . SER E 5 128 ? 112.145 158.073 180.042 1.00 127.44 ? 128 SER N CB  1 
# 
