data_8TX4
# 
_entry.id   8TX4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8TX4         pdb_00008tx4 10.2210/pdb8tx4/pdb 
WWPDB D_1000276769 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-06 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8TX4 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              xiaojiac@usc.edu 
_pdbx_contact_author.name_first         Xiaojiang 
_pdbx_contact_author.name_last          Chen 
_pdbx_contact_author.name_mi            S 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9574-0551 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, H.'      1 0000-0001-7187-3720 
'Pacheco, J.I.' 2 0000-0002-3094-3283 
'Chen, X.S.'    3 0000-0001-9574-0551 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                8773 
_citation.page_last                 8773 
_citation.title                     'Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-52671-1 
_citation.pdbx_database_id_PubMed   39389938 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, H.'     1 0000-0001-7187-3720 
primary 'Pacheco, J.'  2 0000-0002-3094-3283 
primary 'Kim, K.'      3 ?                   
primary 'Bokani, A.'   4 ?                   
primary 'Ito, F.'      5 0000-0002-2274-118X 
primary 'Ebrahimi, D.' 6 ?                   
primary 'Chen, X.S.'   7 0000-0001-9574-0551 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'DNA dC->dU-editing enzyme APOBEC-3G'         45199.633 1   3.5.4.- ? ? ? 
2 polymer     syn 
;DNA 22-mer with (5'-D(P*TP*GP*AP*TP*TP)-3')
;
6636.278  1   ?       ? ? ? 
3 non-polymer syn 'ZINC ION'                                    65.409    2   ?       ? ? ? 
4 non-polymer syn 'PHOSPHATE ION'                               94.971    1   ?       ? ? ? 
5 water       nat water                                         18.015    333 ?       ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Deoxycytidine deaminase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;GPGGSGGMKPQIRNMVEPMDPRTFVSNFNNRPILSGLDTVWLCCEVKTKDPSGPPLDAKIFQGKVYPKAKYHPEMRFLRW
FHKWRQLHHDQEYKVTWYVSWSPCTRCANSVATFLAKDPKVTLTIFVARLYYFWKPDYQQALRILAEAGATMKIMNYNEF
QDCWNKFVDGRGKPFKPWNNLPKHYTLLQATLGELLRHLMDPGTFTSNFNNKPWVSGQHETYLCYKVERLHNDTWVPLNQ
HRGFLRNQAPNIHGFPKGRHAALCFLDLIPFWKLDGQQYRVTCFTSWSPCFSCAQEMAKFISNNEHVSLCIFAARIYDDQ
GRYQEGLRTLHRDGAKIAMMNYSEFEYCWDTFVDRQGRPFQPWDGLDEHSQALSGRLRAILQNILQ
;
;GPGGSGGMKPQIRNMVEPMDPRTFVSNFNNRPILSGLDTVWLCCEVKTKDPSGPPLDAKIFQGKVYPKAKYHPEMRFLRW
FHKWRQLHHDQEYKVTWYVSWSPCTRCANSVATFLAKDPKVTLTIFVARLYYFWKPDYQQALRILAEAGATMKIMNYNEF
QDCWNKFVDGRGKPFKPWNNLPKHYTLLQATLGELLRHLMDPGTFTSNFNNKPWVSGQHETYLCYKVERLHNDTWVPLNQ
HRGFLRNQAPNIHGFPKGRHAALCFLDLIPFWKLDGQQYRVTCFTSWSPCFSCAQEMAKFISNNEHVSLCIFAARIYDDQ
GRYQEGLRTLHRDGAKIAMMNYSEFEYCWDTFVDRQGRPFQPWDGLDEHSQALSGRLRAILQNILQ
;
A ? 
2 polydeoxyribonucleotide no no 
;(DT)(DT)(DT)(DC)(DC)(DC)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DG)(DA)(DT)(DT)
(DT)(DT)
;
TTTCCCTTTTTTTTTTGATTTT B ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'ZINC ION'      ZN  
4 'PHOSPHATE ION' PO4 
5 water           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   GLY n 
1 5   SER n 
1 6   GLY n 
1 7   GLY n 
1 8   MET n 
1 9   LYS n 
1 10  PRO n 
1 11  GLN n 
1 12  ILE n 
1 13  ARG n 
1 14  ASN n 
1 15  MET n 
1 16  VAL n 
1 17  GLU n 
1 18  PRO n 
1 19  MET n 
1 20  ASP n 
1 21  PRO n 
1 22  ARG n 
1 23  THR n 
1 24  PHE n 
1 25  VAL n 
1 26  SER n 
1 27  ASN n 
1 28  PHE n 
1 29  ASN n 
1 30  ASN n 
1 31  ARG n 
1 32  PRO n 
1 33  ILE n 
1 34  LEU n 
1 35  SER n 
1 36  GLY n 
1 37  LEU n 
1 38  ASP n 
1 39  THR n 
1 40  VAL n 
1 41  TRP n 
1 42  LEU n 
1 43  CYS n 
1 44  CYS n 
1 45  GLU n 
1 46  VAL n 
1 47  LYS n 
1 48  THR n 
1 49  LYS n 
1 50  ASP n 
1 51  PRO n 
1 52  SER n 
1 53  GLY n 
1 54  PRO n 
1 55  PRO n 
1 56  LEU n 
1 57  ASP n 
1 58  ALA n 
1 59  LYS n 
1 60  ILE n 
1 61  PHE n 
1 62  GLN n 
1 63  GLY n 
1 64  LYS n 
1 65  VAL n 
1 66  TYR n 
1 67  PRO n 
1 68  LYS n 
1 69  ALA n 
1 70  LYS n 
1 71  TYR n 
1 72  HIS n 
1 73  PRO n 
1 74  GLU n 
1 75  MET n 
1 76  ARG n 
1 77  PHE n 
1 78  LEU n 
1 79  ARG n 
1 80  TRP n 
1 81  PHE n 
1 82  HIS n 
1 83  LYS n 
1 84  TRP n 
1 85  ARG n 
1 86  GLN n 
1 87  LEU n 
1 88  HIS n 
1 89  HIS n 
1 90  ASP n 
1 91  GLN n 
1 92  GLU n 
1 93  TYR n 
1 94  LYS n 
1 95  VAL n 
1 96  THR n 
1 97  TRP n 
1 98  TYR n 
1 99  VAL n 
1 100 SER n 
1 101 TRP n 
1 102 SER n 
1 103 PRO n 
1 104 CYS n 
1 105 THR n 
1 106 ARG n 
1 107 CYS n 
1 108 ALA n 
1 109 ASN n 
1 110 SER n 
1 111 VAL n 
1 112 ALA n 
1 113 THR n 
1 114 PHE n 
1 115 LEU n 
1 116 ALA n 
1 117 LYS n 
1 118 ASP n 
1 119 PRO n 
1 120 LYS n 
1 121 VAL n 
1 122 THR n 
1 123 LEU n 
1 124 THR n 
1 125 ILE n 
1 126 PHE n 
1 127 VAL n 
1 128 ALA n 
1 129 ARG n 
1 130 LEU n 
1 131 TYR n 
1 132 TYR n 
1 133 PHE n 
1 134 TRP n 
1 135 LYS n 
1 136 PRO n 
1 137 ASP n 
1 138 TYR n 
1 139 GLN n 
1 140 GLN n 
1 141 ALA n 
1 142 LEU n 
1 143 ARG n 
1 144 ILE n 
1 145 LEU n 
1 146 ALA n 
1 147 GLU n 
1 148 ALA n 
1 149 GLY n 
1 150 ALA n 
1 151 THR n 
1 152 MET n 
1 153 LYS n 
1 154 ILE n 
1 155 MET n 
1 156 ASN n 
1 157 TYR n 
1 158 ASN n 
1 159 GLU n 
1 160 PHE n 
1 161 GLN n 
1 162 ASP n 
1 163 CYS n 
1 164 TRP n 
1 165 ASN n 
1 166 LYS n 
1 167 PHE n 
1 168 VAL n 
1 169 ASP n 
1 170 GLY n 
1 171 ARG n 
1 172 GLY n 
1 173 LYS n 
1 174 PRO n 
1 175 PHE n 
1 176 LYS n 
1 177 PRO n 
1 178 TRP n 
1 179 ASN n 
1 180 ASN n 
1 181 LEU n 
1 182 PRO n 
1 183 LYS n 
1 184 HIS n 
1 185 TYR n 
1 186 THR n 
1 187 LEU n 
1 188 LEU n 
1 189 GLN n 
1 190 ALA n 
1 191 THR n 
1 192 LEU n 
1 193 GLY n 
1 194 GLU n 
1 195 LEU n 
1 196 LEU n 
1 197 ARG n 
1 198 HIS n 
1 199 LEU n 
1 200 MET n 
1 201 ASP n 
1 202 PRO n 
1 203 GLY n 
1 204 THR n 
1 205 PHE n 
1 206 THR n 
1 207 SER n 
1 208 ASN n 
1 209 PHE n 
1 210 ASN n 
1 211 ASN n 
1 212 LYS n 
1 213 PRO n 
1 214 TRP n 
1 215 VAL n 
1 216 SER n 
1 217 GLY n 
1 218 GLN n 
1 219 HIS n 
1 220 GLU n 
1 221 THR n 
1 222 TYR n 
1 223 LEU n 
1 224 CYS n 
1 225 TYR n 
1 226 LYS n 
1 227 VAL n 
1 228 GLU n 
1 229 ARG n 
1 230 LEU n 
1 231 HIS n 
1 232 ASN n 
1 233 ASP n 
1 234 THR n 
1 235 TRP n 
1 236 VAL n 
1 237 PRO n 
1 238 LEU n 
1 239 ASN n 
1 240 GLN n 
1 241 HIS n 
1 242 ARG n 
1 243 GLY n 
1 244 PHE n 
1 245 LEU n 
1 246 ARG n 
1 247 ASN n 
1 248 GLN n 
1 249 ALA n 
1 250 PRO n 
1 251 ASN n 
1 252 ILE n 
1 253 HIS n 
1 254 GLY n 
1 255 PHE n 
1 256 PRO n 
1 257 LYS n 
1 258 GLY n 
1 259 ARG n 
1 260 HIS n 
1 261 ALA n 
1 262 ALA n 
1 263 LEU n 
1 264 CYS n 
1 265 PHE n 
1 266 LEU n 
1 267 ASP n 
1 268 LEU n 
1 269 ILE n 
1 270 PRO n 
1 271 PHE n 
1 272 TRP n 
1 273 LYS n 
1 274 LEU n 
1 275 ASP n 
1 276 GLY n 
1 277 GLN n 
1 278 GLN n 
1 279 TYR n 
1 280 ARG n 
1 281 VAL n 
1 282 THR n 
1 283 CYS n 
1 284 PHE n 
1 285 THR n 
1 286 SER n 
1 287 TRP n 
1 288 SER n 
1 289 PRO n 
1 290 CYS n 
1 291 PHE n 
1 292 SER n 
1 293 CYS n 
1 294 ALA n 
1 295 GLN n 
1 296 GLU n 
1 297 MET n 
1 298 ALA n 
1 299 LYS n 
1 300 PHE n 
1 301 ILE n 
1 302 SER n 
1 303 ASN n 
1 304 ASN n 
1 305 GLU n 
1 306 HIS n 
1 307 VAL n 
1 308 SER n 
1 309 LEU n 
1 310 CYS n 
1 311 ILE n 
1 312 PHE n 
1 313 ALA n 
1 314 ALA n 
1 315 ARG n 
1 316 ILE n 
1 317 TYR n 
1 318 ASP n 
1 319 ASP n 
1 320 GLN n 
1 321 GLY n 
1 322 ARG n 
1 323 TYR n 
1 324 GLN n 
1 325 GLU n 
1 326 GLY n 
1 327 LEU n 
1 328 ARG n 
1 329 THR n 
1 330 LEU n 
1 331 HIS n 
1 332 ARG n 
1 333 ASP n 
1 334 GLY n 
1 335 ALA n 
1 336 LYS n 
1 337 ILE n 
1 338 ALA n 
1 339 MET n 
1 340 MET n 
1 341 ASN n 
1 342 TYR n 
1 343 SER n 
1 344 GLU n 
1 345 PHE n 
1 346 GLU n 
1 347 TYR n 
1 348 CYS n 
1 349 TRP n 
1 350 ASP n 
1 351 THR n 
1 352 PHE n 
1 353 VAL n 
1 354 ASP n 
1 355 ARG n 
1 356 GLN n 
1 357 GLY n 
1 358 ARG n 
1 359 PRO n 
1 360 PHE n 
1 361 GLN n 
1 362 PRO n 
1 363 TRP n 
1 364 ASP n 
1 365 GLY n 
1 366 LEU n 
1 367 ASP n 
1 368 GLU n 
1 369 HIS n 
1 370 SER n 
1 371 GLN n 
1 372 ALA n 
1 373 LEU n 
1 374 SER n 
1 375 GLY n 
1 376 ARG n 
1 377 LEU n 
1 378 ARG n 
1 379 ALA n 
1 380 ILE n 
1 381 LEU n 
1 382 GLN n 
1 383 ASN n 
1 384 ILE n 
1 385 LEU n 
1 386 GLN n 
2 1   DT  n 
2 2   DT  n 
2 3   DT  n 
2 4   DC  n 
2 5   DC  n 
2 6   DC  n 
2 7   DT  n 
2 8   DT  n 
2 9   DT  n 
2 10  DT  n 
2 11  DT  n 
2 12  DT  n 
2 13  DT  n 
2 14  DT  n 
2 15  DT  n 
2 16  DT  n 
2 17  DG  n 
2 18  DA  n 
2 19  DT  n 
2 20  DT  n 
2 21  DT  n 
2 22  DT  n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   386 
_entity_src_gen.gene_src_common_name               'Rhesus monkey' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 APOBEC3G 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Macaca mulatta' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9544 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       22 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                ? 'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PO4 non-polymer         . 'PHOSPHATE ION'                      ? 'O4 P -3'         94.971  
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
ZN  non-polymer         . 'ZINC ION'                           ? 'Zn 2'            65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -6  ?   ?   ?   A . n 
A 1 2   PRO 2   -5  ?   ?   ?   A . n 
A 1 3   GLY 3   -4  ?   ?   ?   A . n 
A 1 4   GLY 4   -3  ?   ?   ?   A . n 
A 1 5   SER 5   -2  ?   ?   ?   A . n 
A 1 6   GLY 6   -1  ?   ?   ?   A . n 
A 1 7   GLY 7   0   ?   ?   ?   A . n 
A 1 8   MET 8   1   ?   ?   ?   A . n 
A 1 9   LYS 9   2   ?   ?   ?   A . n 
A 1 10  PRO 10  3   ?   ?   ?   A . n 
A 1 11  GLN 11  4   4   GLN GLN A . n 
A 1 12  ILE 12  5   5   ILE ILE A . n 
A 1 13  ARG 13  6   6   ARG ARG A . n 
A 1 14  ASN 14  7   7   ASN ASN A . n 
A 1 15  MET 15  8   8   MET MET A . n 
A 1 16  VAL 16  9   9   VAL VAL A . n 
A 1 17  GLU 17  10  10  GLU GLU A . n 
A 1 18  PRO 18  11  11  PRO PRO A . n 
A 1 19  MET 19  12  12  MET MET A . n 
A 1 20  ASP 20  13  13  ASP ASP A . n 
A 1 21  PRO 21  14  14  PRO PRO A . n 
A 1 22  ARG 22  15  15  ARG ARG A . n 
A 1 23  THR 23  16  16  THR THR A . n 
A 1 24  PHE 24  17  17  PHE PHE A . n 
A 1 25  VAL 25  18  18  VAL VAL A . n 
A 1 26  SER 26  19  19  SER SER A . n 
A 1 27  ASN 27  20  20  ASN ASN A . n 
A 1 28  PHE 28  21  21  PHE PHE A . n 
A 1 29  ASN 29  22  22  ASN ASN A . n 
A 1 30  ASN 30  23  23  ASN ASN A . n 
A 1 31  ARG 31  24  24  ARG ARG A . n 
A 1 32  PRO 32  25  25  PRO PRO A . n 
A 1 33  ILE 33  26  26  ILE ILE A . n 
A 1 34  LEU 34  27  27  LEU LEU A . n 
A 1 35  SER 35  28  28  SER SER A . n 
A 1 36  GLY 36  29  29  GLY GLY A . n 
A 1 37  LEU 37  30  30  LEU LEU A . n 
A 1 38  ASP 38  31  31  ASP ASP A . n 
A 1 39  THR 39  32  32  THR THR A . n 
A 1 40  VAL 40  33  33  VAL VAL A . n 
A 1 41  TRP 41  34  34  TRP TRP A . n 
A 1 42  LEU 42  35  35  LEU LEU A . n 
A 1 43  CYS 43  36  36  CYS CYS A . n 
A 1 44  CYS 44  37  37  CYS CYS A . n 
A 1 45  GLU 45  38  38  GLU GLU A . n 
A 1 46  VAL 46  39  39  VAL VAL A . n 
A 1 47  LYS 47  40  40  LYS LYS A . n 
A 1 48  THR 48  41  41  THR THR A . n 
A 1 49  LYS 49  42  42  LYS LYS A . n 
A 1 50  ASP 50  43  43  ASP ASP A . n 
A 1 51  PRO 51  44  44  PRO PRO A . n 
A 1 52  SER 52  45  45  SER SER A . n 
A 1 53  GLY 53  46  46  GLY GLY A . n 
A 1 54  PRO 54  47  47  PRO PRO A . n 
A 1 55  PRO 55  48  48  PRO PRO A . n 
A 1 56  LEU 56  49  49  LEU LEU A . n 
A 1 57  ASP 57  50  50  ASP ASP A . n 
A 1 58  ALA 58  51  51  ALA ALA A . n 
A 1 59  LYS 59  52  52  LYS LYS A . n 
A 1 60  ILE 60  53  53  ILE ILE A . n 
A 1 61  PHE 61  54  54  PHE PHE A . n 
A 1 62  GLN 62  55  55  GLN GLN A . n 
A 1 63  GLY 63  56  56  GLY GLY A . n 
A 1 64  LYS 64  57  57  LYS LYS A . n 
A 1 65  VAL 65  58  58  VAL VAL A . n 
A 1 66  TYR 66  59  59  TYR TYR A . n 
A 1 67  PRO 67  60  60  PRO PRO A . n 
A 1 68  LYS 68  61  61  LYS LYS A . n 
A 1 69  ALA 69  62  62  ALA ALA A . n 
A 1 70  LYS 70  63  63  LYS LYS A . n 
A 1 71  TYR 71  64  64  TYR TYR A . n 
A 1 72  HIS 72  65  65  HIS HIS A . n 
A 1 73  PRO 73  66  66  PRO PRO A . n 
A 1 74  GLU 74  67  67  GLU GLU A . n 
A 1 75  MET 75  68  68  MET MET A . n 
A 1 76  ARG 76  69  69  ARG ARG A . n 
A 1 77  PHE 77  70  70  PHE PHE A . n 
A 1 78  LEU 78  71  71  LEU LEU A . n 
A 1 79  ARG 79  72  72  ARG ARG A . n 
A 1 80  TRP 80  73  73  TRP TRP A . n 
A 1 81  PHE 81  74  74  PHE PHE A . n 
A 1 82  HIS 82  75  75  HIS HIS A . n 
A 1 83  LYS 83  76  76  LYS LYS A . n 
A 1 84  TRP 84  77  77  TRP TRP A . n 
A 1 85  ARG 85  78  78  ARG ARG A . n 
A 1 86  GLN 86  79  79  GLN GLN A . n 
A 1 87  LEU 87  80  80  LEU LEU A . n 
A 1 88  HIS 88  81  81  HIS HIS A . n 
A 1 89  HIS 89  82  82  HIS HIS A . n 
A 1 90  ASP 90  83  83  ASP ASP A . n 
A 1 91  GLN 91  84  84  GLN GLN A . n 
A 1 92  GLU 92  85  85  GLU GLU A . n 
A 1 93  TYR 93  86  86  TYR TYR A . n 
A 1 94  LYS 94  87  87  LYS LYS A . n 
A 1 95  VAL 95  88  88  VAL VAL A . n 
A 1 96  THR 96  89  89  THR THR A . n 
A 1 97  TRP 97  90  90  TRP TRP A . n 
A 1 98  TYR 98  91  91  TYR TYR A . n 
A 1 99  VAL 99  92  92  VAL VAL A . n 
A 1 100 SER 100 93  93  SER SER A . n 
A 1 101 TRP 101 94  94  TRP TRP A . n 
A 1 102 SER 102 95  95  SER SER A . n 
A 1 103 PRO 103 96  96  PRO PRO A . n 
A 1 104 CYS 104 97  97  CYS CYS A . n 
A 1 105 THR 105 98  98  THR THR A . n 
A 1 106 ARG 106 99  99  ARG ARG A . n 
A 1 107 CYS 107 100 100 CYS CYS A . n 
A 1 108 ALA 108 101 101 ALA ALA A . n 
A 1 109 ASN 109 102 102 ASN ASN A . n 
A 1 110 SER 110 103 103 SER SER A . n 
A 1 111 VAL 111 104 104 VAL VAL A . n 
A 1 112 ALA 112 105 105 ALA ALA A . n 
A 1 113 THR 113 106 106 THR THR A . n 
A 1 114 PHE 114 107 107 PHE PHE A . n 
A 1 115 LEU 115 108 108 LEU LEU A . n 
A 1 116 ALA 116 109 109 ALA ALA A . n 
A 1 117 LYS 117 110 110 LYS LYS A . n 
A 1 118 ASP 118 111 111 ASP ASP A . n 
A 1 119 PRO 119 112 112 PRO PRO A . n 
A 1 120 LYS 120 113 113 LYS LYS A . n 
A 1 121 VAL 121 114 114 VAL VAL A . n 
A 1 122 THR 122 115 115 THR THR A . n 
A 1 123 LEU 123 116 116 LEU LEU A . n 
A 1 124 THR 124 117 117 THR THR A . n 
A 1 125 ILE 125 118 118 ILE ILE A . n 
A 1 126 PHE 126 119 119 PHE PHE A . n 
A 1 127 VAL 127 120 120 VAL VAL A . n 
A 1 128 ALA 128 121 121 ALA ALA A . n 
A 1 129 ARG 129 122 122 ARG ARG A . n 
A 1 130 LEU 130 123 123 LEU LEU A . n 
A 1 131 TYR 131 124 124 TYR TYR A . n 
A 1 132 TYR 132 125 125 TYR TYR A . n 
A 1 133 PHE 133 126 126 PHE PHE A . n 
A 1 134 TRP 134 127 127 TRP TRP A . n 
A 1 135 LYS 135 128 128 LYS LYS A . n 
A 1 136 PRO 136 129 129 PRO PRO A . n 
A 1 137 ASP 137 130 130 ASP ASP A . n 
A 1 138 TYR 138 131 131 TYR TYR A . n 
A 1 139 GLN 139 132 132 GLN GLN A . n 
A 1 140 GLN 140 133 133 GLN GLN A . n 
A 1 141 ALA 141 134 134 ALA ALA A . n 
A 1 142 LEU 142 135 135 LEU LEU A . n 
A 1 143 ARG 143 136 136 ARG ARG A . n 
A 1 144 ILE 144 137 137 ILE ILE A . n 
A 1 145 LEU 145 138 138 LEU LEU A . n 
A 1 146 ALA 146 139 139 ALA ALA A . n 
A 1 147 GLU 147 140 140 GLU GLU A . n 
A 1 148 ALA 148 141 141 ALA ALA A . n 
A 1 149 GLY 149 142 142 GLY GLY A . n 
A 1 150 ALA 150 147 147 ALA ALA A . n 
A 1 151 THR 151 148 148 THR THR A . n 
A 1 152 MET 152 149 149 MET MET A . n 
A 1 153 LYS 153 150 150 LYS LYS A . n 
A 1 154 ILE 154 151 151 ILE ILE A . n 
A 1 155 MET 155 152 152 MET MET A . n 
A 1 156 ASN 156 153 153 ASN ASN A . n 
A 1 157 TYR 157 154 154 TYR TYR A . n 
A 1 158 ASN 158 155 155 ASN ASN A . n 
A 1 159 GLU 159 156 156 GLU GLU A . n 
A 1 160 PHE 160 157 157 PHE PHE A . n 
A 1 161 GLN 161 158 158 GLN GLN A . n 
A 1 162 ASP 162 159 159 ASP ASP A . n 
A 1 163 CYS 163 160 160 CYS CYS A . n 
A 1 164 TRP 164 161 161 TRP TRP A . n 
A 1 165 ASN 165 162 162 ASN ASN A . n 
A 1 166 LYS 166 163 163 LYS LYS A . n 
A 1 167 PHE 167 164 164 PHE PHE A . n 
A 1 168 VAL 168 165 165 VAL VAL A . n 
A 1 169 ASP 169 166 166 ASP ASP A . n 
A 1 170 GLY 170 167 167 GLY GLY A . n 
A 1 171 ARG 171 168 168 ARG ARG A . n 
A 1 172 GLY 172 169 169 GLY GLY A . n 
A 1 173 LYS 173 170 170 LYS LYS A . n 
A 1 174 PRO 174 171 171 PRO PRO A . n 
A 1 175 PHE 175 172 172 PHE PHE A . n 
A 1 176 LYS 176 173 173 LYS LYS A . n 
A 1 177 PRO 177 174 174 PRO PRO A . n 
A 1 178 TRP 178 175 175 TRP TRP A . n 
A 1 179 ASN 179 176 176 ASN ASN A . n 
A 1 180 ASN 180 177 177 ASN ASN A . n 
A 1 181 LEU 181 178 178 LEU LEU A . n 
A 1 182 PRO 182 179 179 PRO PRO A . n 
A 1 183 LYS 183 180 180 LYS LYS A . n 
A 1 184 HIS 184 181 181 HIS HIS A . n 
A 1 185 TYR 185 182 182 TYR TYR A . n 
A 1 186 THR 186 183 183 THR THR A . n 
A 1 187 LEU 187 184 184 LEU LEU A . n 
A 1 188 LEU 188 185 185 LEU LEU A . n 
A 1 189 GLN 189 186 186 GLN GLN A . n 
A 1 190 ALA 190 187 187 ALA ALA A . n 
A 1 191 THR 191 188 188 THR THR A . n 
A 1 192 LEU 192 189 189 LEU LEU A . n 
A 1 193 GLY 193 190 190 GLY GLY A . n 
A 1 194 GLU 194 191 191 GLU GLU A . n 
A 1 195 LEU 195 192 192 LEU LEU A . n 
A 1 196 LEU 196 193 193 LEU LEU A . n 
A 1 197 ARG 197 194 194 ARG ARG A . n 
A 1 198 HIS 198 195 195 HIS HIS A . n 
A 1 199 LEU 199 196 196 LEU LEU A . n 
A 1 200 MET 200 197 197 MET MET A . n 
A 1 201 ASP 201 198 198 ASP ASP A . n 
A 1 202 PRO 202 199 199 PRO PRO A . n 
A 1 203 GLY 203 200 200 GLY GLY A . n 
A 1 204 THR 204 201 201 THR THR A . n 
A 1 205 PHE 205 202 202 PHE PHE A . n 
A 1 206 THR 206 203 203 THR THR A . n 
A 1 207 SER 207 204 204 SER SER A . n 
A 1 208 ASN 208 205 205 ASN ASN A . n 
A 1 209 PHE 209 206 206 PHE PHE A . n 
A 1 210 ASN 210 207 207 ASN ASN A . n 
A 1 211 ASN 211 208 208 ASN ASN A . n 
A 1 212 LYS 212 209 209 LYS LYS A . n 
A 1 213 PRO 213 210 210 PRO PRO A . n 
A 1 214 TRP 214 211 211 TRP TRP A . n 
A 1 215 VAL 215 212 212 VAL VAL A . n 
A 1 216 SER 216 213 213 SER SER A . n 
A 1 217 GLY 217 214 214 GLY GLY A . n 
A 1 218 GLN 218 215 215 GLN GLN A . n 
A 1 219 HIS 219 216 216 HIS HIS A . n 
A 1 220 GLU 220 217 217 GLU GLU A . n 
A 1 221 THR 221 218 218 THR THR A . n 
A 1 222 TYR 222 219 219 TYR TYR A . n 
A 1 223 LEU 223 220 220 LEU LEU A . n 
A 1 224 CYS 224 221 221 CYS CYS A . n 
A 1 225 TYR 225 222 222 TYR TYR A . n 
A 1 226 LYS 226 223 223 LYS LYS A . n 
A 1 227 VAL 227 224 224 VAL VAL A . n 
A 1 228 GLU 228 225 225 GLU GLU A . n 
A 1 229 ARG 229 226 226 ARG ARG A . n 
A 1 230 LEU 230 227 227 LEU LEU A . n 
A 1 231 HIS 231 228 228 HIS HIS A . n 
A 1 232 ASN 232 229 229 ASN ASN A . n 
A 1 233 ASP 233 230 230 ASP ASP A . n 
A 1 234 THR 234 231 231 THR THR A . n 
A 1 235 TRP 235 232 232 TRP TRP A . n 
A 1 236 VAL 236 233 233 VAL VAL A . n 
A 1 237 PRO 237 234 234 PRO PRO A . n 
A 1 238 LEU 238 235 235 LEU LEU A . n 
A 1 239 ASN 239 236 236 ASN ASN A . n 
A 1 240 GLN 240 237 237 GLN GLN A . n 
A 1 241 HIS 241 238 238 HIS HIS A . n 
A 1 242 ARG 242 239 239 ARG ARG A . n 
A 1 243 GLY 243 240 240 GLY GLY A . n 
A 1 244 PHE 244 241 241 PHE PHE A . n 
A 1 245 LEU 245 242 242 LEU LEU A . n 
A 1 246 ARG 246 243 243 ARG ARG A . n 
A 1 247 ASN 247 244 244 ASN ASN A . n 
A 1 248 GLN 248 245 245 GLN GLN A . n 
A 1 249 ALA 249 246 246 ALA ALA A . n 
A 1 250 PRO 250 247 247 PRO PRO A . n 
A 1 251 ASN 251 248 248 ASN ASN A . n 
A 1 252 ILE 252 249 249 ILE ILE A . n 
A 1 253 HIS 253 250 250 HIS HIS A . n 
A 1 254 GLY 254 251 251 GLY GLY A . n 
A 1 255 PHE 255 252 252 PHE PHE A . n 
A 1 256 PRO 256 253 253 PRO PRO A . n 
A 1 257 LYS 257 254 254 LYS LYS A . n 
A 1 258 GLY 258 255 255 GLY GLY A . n 
A 1 259 ARG 259 256 256 ARG ARG A . n 
A 1 260 HIS 260 257 257 HIS HIS A . n 
A 1 261 ALA 261 258 258 ALA ALA A . n 
A 1 262 ALA 262 259 259 ALA ALA A . n 
A 1 263 LEU 263 260 260 LEU LEU A . n 
A 1 264 CYS 264 261 261 CYS CYS A . n 
A 1 265 PHE 265 262 262 PHE PHE A . n 
A 1 266 LEU 266 263 263 LEU LEU A . n 
A 1 267 ASP 267 264 264 ASP ASP A . n 
A 1 268 LEU 268 265 265 LEU LEU A . n 
A 1 269 ILE 269 266 266 ILE ILE A . n 
A 1 270 PRO 270 267 267 PRO PRO A . n 
A 1 271 PHE 271 268 268 PHE PHE A . n 
A 1 272 TRP 272 269 269 TRP TRP A . n 
A 1 273 LYS 273 270 270 LYS LYS A . n 
A 1 274 LEU 274 271 271 LEU LEU A . n 
A 1 275 ASP 275 272 272 ASP ASP A . n 
A 1 276 GLY 276 273 273 GLY GLY A . n 
A 1 277 GLN 277 274 274 GLN GLN A . n 
A 1 278 GLN 278 275 275 GLN GLN A . n 
A 1 279 TYR 279 276 276 TYR TYR A . n 
A 1 280 ARG 280 277 277 ARG ARG A . n 
A 1 281 VAL 281 278 278 VAL VAL A . n 
A 1 282 THR 282 279 279 THR THR A . n 
A 1 283 CYS 283 280 280 CYS CYS A . n 
A 1 284 PHE 284 281 281 PHE PHE A . n 
A 1 285 THR 285 282 282 THR THR A . n 
A 1 286 SER 286 283 283 SER SER A . n 
A 1 287 TRP 287 284 284 TRP TRP A . n 
A 1 288 SER 288 285 285 SER SER A . n 
A 1 289 PRO 289 286 286 PRO PRO A . n 
A 1 290 CYS 290 287 287 CYS CYS A . n 
A 1 291 PHE 291 288 288 PHE PHE A . n 
A 1 292 SER 292 289 289 SER SER A . n 
A 1 293 CYS 293 290 290 CYS CYS A . n 
A 1 294 ALA 294 291 291 ALA ALA A . n 
A 1 295 GLN 295 292 292 GLN GLN A . n 
A 1 296 GLU 296 293 293 GLU GLU A . n 
A 1 297 MET 297 294 294 MET MET A . n 
A 1 298 ALA 298 295 295 ALA ALA A . n 
A 1 299 LYS 299 296 296 LYS LYS A . n 
A 1 300 PHE 300 297 297 PHE PHE A . n 
A 1 301 ILE 301 298 298 ILE ILE A . n 
A 1 302 SER 302 299 299 SER SER A . n 
A 1 303 ASN 303 300 300 ASN ASN A . n 
A 1 304 ASN 304 301 301 ASN ASN A . n 
A 1 305 GLU 305 302 302 GLU GLU A . n 
A 1 306 HIS 306 303 303 HIS HIS A . n 
A 1 307 VAL 307 304 304 VAL VAL A . n 
A 1 308 SER 308 305 305 SER SER A . n 
A 1 309 LEU 309 306 306 LEU LEU A . n 
A 1 310 CYS 310 307 307 CYS CYS A . n 
A 1 311 ILE 311 308 308 ILE ILE A . n 
A 1 312 PHE 312 309 309 PHE PHE A . n 
A 1 313 ALA 313 310 310 ALA ALA A . n 
A 1 314 ALA 314 311 311 ALA ALA A . n 
A 1 315 ARG 315 312 312 ARG ARG A . n 
A 1 316 ILE 316 313 313 ILE ILE A . n 
A 1 317 TYR 317 314 314 TYR TYR A . n 
A 1 318 ASP 318 315 315 ASP ASP A . n 
A 1 319 ASP 319 316 316 ASP ASP A . n 
A 1 320 GLN 320 317 317 GLN GLN A . n 
A 1 321 GLY 321 318 318 GLY GLY A . n 
A 1 322 ARG 322 319 319 ARG ARG A . n 
A 1 323 TYR 323 320 320 TYR TYR A . n 
A 1 324 GLN 324 321 321 GLN GLN A . n 
A 1 325 GLU 325 322 322 GLU GLU A . n 
A 1 326 GLY 326 323 323 GLY GLY A . n 
A 1 327 LEU 327 324 324 LEU LEU A . n 
A 1 328 ARG 328 325 325 ARG ARG A . n 
A 1 329 THR 329 326 326 THR THR A . n 
A 1 330 LEU 330 327 327 LEU LEU A . n 
A 1 331 HIS 331 328 328 HIS HIS A . n 
A 1 332 ARG 332 329 329 ARG ARG A . n 
A 1 333 ASP 333 330 330 ASP ASP A . n 
A 1 334 GLY 334 331 331 GLY GLY A . n 
A 1 335 ALA 335 332 332 ALA ALA A . n 
A 1 336 LYS 336 333 333 LYS LYS A . n 
A 1 337 ILE 337 334 334 ILE ILE A . n 
A 1 338 ALA 338 335 335 ALA ALA A . n 
A 1 339 MET 339 336 336 MET MET A . n 
A 1 340 MET 340 337 337 MET MET A . n 
A 1 341 ASN 341 338 338 ASN ASN A . n 
A 1 342 TYR 342 339 339 TYR TYR A . n 
A 1 343 SER 343 340 340 SER SER A . n 
A 1 344 GLU 344 341 341 GLU GLU A . n 
A 1 345 PHE 345 342 342 PHE PHE A . n 
A 1 346 GLU 346 343 343 GLU GLU A . n 
A 1 347 TYR 347 344 344 TYR TYR A . n 
A 1 348 CYS 348 345 345 CYS CYS A . n 
A 1 349 TRP 349 346 346 TRP TRP A . n 
A 1 350 ASP 350 347 347 ASP ASP A . n 
A 1 351 THR 351 348 348 THR THR A . n 
A 1 352 PHE 352 349 349 PHE PHE A . n 
A 1 353 VAL 353 350 350 VAL VAL A . n 
A 1 354 ASP 354 351 351 ASP ASP A . n 
A 1 355 ARG 355 352 352 ARG ARG A . n 
A 1 356 GLN 356 353 353 GLN GLN A . n 
A 1 357 GLY 357 354 354 GLY GLY A . n 
A 1 358 ARG 358 355 355 ARG ARG A . n 
A 1 359 PRO 359 356 356 PRO PRO A . n 
A 1 360 PHE 360 357 357 PHE PHE A . n 
A 1 361 GLN 361 358 358 GLN GLN A . n 
A 1 362 PRO 362 359 359 PRO PRO A . n 
A 1 363 TRP 363 360 360 TRP TRP A . n 
A 1 364 ASP 364 361 361 ASP ASP A . n 
A 1 365 GLY 365 362 362 GLY GLY A . n 
A 1 366 LEU 366 363 363 LEU LEU A . n 
A 1 367 ASP 367 364 364 ASP ASP A . n 
A 1 368 GLU 368 365 365 GLU GLU A . n 
A 1 369 HIS 369 366 366 HIS HIS A . n 
A 1 370 SER 370 367 367 SER SER A . n 
A 1 371 GLN 371 368 368 GLN GLN A . n 
A 1 372 ALA 372 369 369 ALA ALA A . n 
A 1 373 LEU 373 370 370 LEU LEU A . n 
A 1 374 SER 374 371 371 SER SER A . n 
A 1 375 GLY 375 372 372 GLY GLY A . n 
A 1 376 ARG 376 373 373 ARG ARG A . n 
A 1 377 LEU 377 374 374 LEU LEU A . n 
A 1 378 ARG 378 375 375 ARG ARG A . n 
A 1 379 ALA 379 376 376 ALA ALA A . n 
A 1 380 ILE 380 377 377 ILE ILE A . n 
A 1 381 LEU 381 378 378 LEU LEU A . n 
A 1 382 GLN 382 379 379 GLN GLN A . n 
A 1 383 ASN 383 380 380 ASN ASN A . n 
A 1 384 ILE 384 381 ?   ?   ?   A . n 
A 1 385 LEU 385 382 ?   ?   ?   A . n 
A 1 386 GLN 386 383 ?   ?   ?   A . n 
B 2 1   DT  1   -5  ?   ?   ?   B . n 
B 2 2   DT  2   -4  ?   ?   ?   B . n 
B 2 3   DT  3   -3  ?   ?   ?   B . n 
B 2 4   DC  4   -2  ?   ?   ?   B . n 
B 2 5   DC  5   -1  ?   ?   ?   B . n 
B 2 6   DC  6   0   ?   ?   ?   B . n 
B 2 7   DT  7   1   ?   ?   ?   B . n 
B 2 8   DT  8   2   ?   ?   ?   B . n 
B 2 9   DT  9   3   ?   ?   ?   B . n 
B 2 10  DT  10  4   ?   ?   ?   B . n 
B 2 11  DT  11  5   ?   ?   ?   B . n 
B 2 12  DT  12  6   ?   ?   ?   B . n 
B 2 13  DT  13  7   ?   ?   ?   B . n 
B 2 14  DT  14  8   ?   ?   ?   B . n 
B 2 15  DT  15  9   ?   ?   ?   B . n 
B 2 16  DT  16  10  16  DT  DT  B . n 
B 2 17  DG  17  11  17  DG  DG  B . n 
B 2 18  DA  18  12  18  DA  DA  B . n 
B 2 19  DT  19  13  19  DT  DT  B . n 
B 2 20  DT  20  14  20  DT  DT  B . n 
B 2 21  DT  21  15  ?   ?   ?   B . n 
B 2 22  DT  22  16  ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 ZN  1   401 805 ZN  ZN  A . 
D 3 ZN  1   402 806 ZN  ZN  A . 
E 4 PO4 1   403 1   PO4 PO4 A . 
F 5 HOH 1   501 41  HOH HOH A . 
F 5 HOH 2   502 274 HOH HOH A . 
F 5 HOH 3   503 317 HOH HOH A . 
F 5 HOH 4   504 265 HOH HOH A . 
F 5 HOH 5   505 321 HOH HOH A . 
F 5 HOH 6   506 152 HOH HOH A . 
F 5 HOH 7   507 84  HOH HOH A . 
F 5 HOH 8   508 243 HOH HOH A . 
F 5 HOH 9   509 31  HOH HOH A . 
F 5 HOH 10  510 54  HOH HOH A . 
F 5 HOH 11  511 213 HOH HOH A . 
F 5 HOH 12  512 13  HOH HOH A . 
F 5 HOH 13  513 36  HOH HOH A . 
F 5 HOH 14  514 48  HOH HOH A . 
F 5 HOH 15  515 197 HOH HOH A . 
F 5 HOH 16  516 219 HOH HOH A . 
F 5 HOH 17  517 222 HOH HOH A . 
F 5 HOH 18  518 239 HOH HOH A . 
F 5 HOH 19  519 32  HOH HOH A . 
F 5 HOH 20  520 91  HOH HOH A . 
F 5 HOH 21  521 164 HOH HOH A . 
F 5 HOH 22  522 75  HOH HOH A . 
F 5 HOH 23  523 77  HOH HOH A . 
F 5 HOH 24  524 30  HOH HOH A . 
F 5 HOH 25  525 104 HOH HOH A . 
F 5 HOH 26  526 67  HOH HOH A . 
F 5 HOH 27  527 114 HOH HOH A . 
F 5 HOH 28  528 134 HOH HOH A . 
F 5 HOH 29  529 220 HOH HOH A . 
F 5 HOH 30  530 21  HOH HOH A . 
F 5 HOH 31  531 95  HOH HOH A . 
F 5 HOH 32  532 272 HOH HOH A . 
F 5 HOH 33  533 4   HOH HOH A . 
F 5 HOH 34  534 206 HOH HOH A . 
F 5 HOH 35  535 45  HOH HOH A . 
F 5 HOH 36  536 81  HOH HOH A . 
F 5 HOH 37  537 303 HOH HOH A . 
F 5 HOH 38  538 100 HOH HOH A . 
F 5 HOH 39  539 195 HOH HOH A . 
F 5 HOH 40  540 271 HOH HOH A . 
F 5 HOH 41  541 63  HOH HOH A . 
F 5 HOH 42  542 69  HOH HOH A . 
F 5 HOH 43  543 335 HOH HOH A . 
F 5 HOH 44  544 260 HOH HOH A . 
F 5 HOH 45  545 10  HOH HOH A . 
F 5 HOH 46  546 94  HOH HOH A . 
F 5 HOH 47  547 157 HOH HOH A . 
F 5 HOH 48  548 58  HOH HOH A . 
F 5 HOH 49  549 57  HOH HOH A . 
F 5 HOH 50  550 233 HOH HOH A . 
F 5 HOH 51  551 49  HOH HOH A . 
F 5 HOH 52  552 123 HOH HOH A . 
F 5 HOH 53  553 327 HOH HOH A . 
F 5 HOH 54  554 252 HOH HOH A . 
F 5 HOH 55  555 96  HOH HOH A . 
F 5 HOH 56  556 3   HOH HOH A . 
F 5 HOH 57  557 293 HOH HOH A . 
F 5 HOH 58  558 237 HOH HOH A . 
F 5 HOH 59  559 9   HOH HOH A . 
F 5 HOH 60  560 72  HOH HOH A . 
F 5 HOH 61  561 240 HOH HOH A . 
F 5 HOH 62  562 5   HOH HOH A . 
F 5 HOH 63  563 24  HOH HOH A . 
F 5 HOH 64  564 193 HOH HOH A . 
F 5 HOH 65  565 137 HOH HOH A . 
F 5 HOH 66  566 171 HOH HOH A . 
F 5 HOH 67  567 26  HOH HOH A . 
F 5 HOH 68  568 18  HOH HOH A . 
F 5 HOH 69  569 83  HOH HOH A . 
F 5 HOH 70  570 131 HOH HOH A . 
F 5 HOH 71  571 178 HOH HOH A . 
F 5 HOH 72  572 135 HOH HOH A . 
F 5 HOH 73  573 6   HOH HOH A . 
F 5 HOH 74  574 154 HOH HOH A . 
F 5 HOH 75  575 309 HOH HOH A . 
F 5 HOH 76  576 198 HOH HOH A . 
F 5 HOH 77  577 125 HOH HOH A . 
F 5 HOH 78  578 101 HOH HOH A . 
F 5 HOH 79  579 187 HOH HOH A . 
F 5 HOH 80  580 51  HOH HOH A . 
F 5 HOH 81  581 61  HOH HOH A . 
F 5 HOH 82  582 149 HOH HOH A . 
F 5 HOH 83  583 287 HOH HOH A . 
F 5 HOH 84  584 146 HOH HOH A . 
F 5 HOH 85  585 262 HOH HOH A . 
F 5 HOH 86  586 191 HOH HOH A . 
F 5 HOH 87  587 59  HOH HOH A . 
F 5 HOH 88  588 60  HOH HOH A . 
F 5 HOH 89  589 43  HOH HOH A . 
F 5 HOH 90  590 74  HOH HOH A . 
F 5 HOH 91  591 14  HOH HOH A . 
F 5 HOH 92  592 153 HOH HOH A . 
F 5 HOH 93  593 270 HOH HOH A . 
F 5 HOH 94  594 210 HOH HOH A . 
F 5 HOH 95  595 7   HOH HOH A . 
F 5 HOH 96  596 65  HOH HOH A . 
F 5 HOH 97  597 2   HOH HOH A . 
F 5 HOH 98  598 105 HOH HOH A . 
F 5 HOH 99  599 70  HOH HOH A . 
F 5 HOH 100 600 204 HOH HOH A . 
F 5 HOH 101 601 16  HOH HOH A . 
F 5 HOH 102 602 25  HOH HOH A . 
F 5 HOH 103 603 33  HOH HOH A . 
F 5 HOH 104 604 130 HOH HOH A . 
F 5 HOH 105 605 185 HOH HOH A . 
F 5 HOH 106 606 53  HOH HOH A . 
F 5 HOH 107 607 218 HOH HOH A . 
F 5 HOH 108 608 86  HOH HOH A . 
F 5 HOH 109 609 15  HOH HOH A . 
F 5 HOH 110 610 118 HOH HOH A . 
F 5 HOH 111 611 99  HOH HOH A . 
F 5 HOH 112 612 192 HOH HOH A . 
F 5 HOH 113 613 40  HOH HOH A . 
F 5 HOH 114 614 174 HOH HOH A . 
F 5 HOH 115 615 283 HOH HOH A . 
F 5 HOH 116 616 147 HOH HOH A . 
F 5 HOH 117 617 44  HOH HOH A . 
F 5 HOH 118 618 119 HOH HOH A . 
F 5 HOH 119 619 227 HOH HOH A . 
F 5 HOH 120 620 124 HOH HOH A . 
F 5 HOH 121 621 28  HOH HOH A . 
F 5 HOH 122 622 121 HOH HOH A . 
F 5 HOH 123 623 12  HOH HOH A . 
F 5 HOH 124 624 150 HOH HOH A . 
F 5 HOH 125 625 143 HOH HOH A . 
F 5 HOH 126 626 223 HOH HOH A . 
F 5 HOH 127 627 253 HOH HOH A . 
F 5 HOH 128 628 140 HOH HOH A . 
F 5 HOH 129 629 8   HOH HOH A . 
F 5 HOH 130 630 136 HOH HOH A . 
F 5 HOH 131 631 116 HOH HOH A . 
F 5 HOH 132 632 109 HOH HOH A . 
F 5 HOH 133 633 168 HOH HOH A . 
F 5 HOH 134 634 92  HOH HOH A . 
F 5 HOH 135 635 120 HOH HOH A . 
F 5 HOH 136 636 259 HOH HOH A . 
F 5 HOH 137 637 38  HOH HOH A . 
F 5 HOH 138 638 201 HOH HOH A . 
F 5 HOH 139 639 93  HOH HOH A . 
F 5 HOH 140 640 228 HOH HOH A . 
F 5 HOH 141 641 27  HOH HOH A . 
F 5 HOH 142 642 166 HOH HOH A . 
F 5 HOH 143 643 79  HOH HOH A . 
F 5 HOH 144 644 159 HOH HOH A . 
F 5 HOH 145 645 22  HOH HOH A . 
F 5 HOH 146 646 279 HOH HOH A . 
F 5 HOH 147 647 68  HOH HOH A . 
F 5 HOH 148 648 141 HOH HOH A . 
F 5 HOH 149 649 263 HOH HOH A . 
F 5 HOH 150 650 208 HOH HOH A . 
F 5 HOH 151 651 230 HOH HOH A . 
F 5 HOH 152 652 73  HOH HOH A . 
F 5 HOH 153 653 76  HOH HOH A . 
F 5 HOH 154 654 142 HOH HOH A . 
F 5 HOH 155 655 50  HOH HOH A . 
F 5 HOH 156 656 331 HOH HOH A . 
F 5 HOH 157 657 82  HOH HOH A . 
F 5 HOH 158 658 242 HOH HOH A . 
F 5 HOH 159 659 34  HOH HOH A . 
F 5 HOH 160 660 98  HOH HOH A . 
F 5 HOH 161 661 182 HOH HOH A . 
F 5 HOH 162 662 55  HOH HOH A . 
F 5 HOH 163 663 211 HOH HOH A . 
F 5 HOH 164 664 29  HOH HOH A . 
F 5 HOH 165 665 245 HOH HOH A . 
F 5 HOH 166 666 66  HOH HOH A . 
F 5 HOH 167 667 207 HOH HOH A . 
F 5 HOH 168 668 88  HOH HOH A . 
F 5 HOH 169 669 173 HOH HOH A . 
F 5 HOH 170 670 158 HOH HOH A . 
F 5 HOH 171 671 42  HOH HOH A . 
F 5 HOH 172 672 291 HOH HOH A . 
F 5 HOH 173 673 226 HOH HOH A . 
F 5 HOH 174 674 117 HOH HOH A . 
F 5 HOH 175 675 184 HOH HOH A . 
F 5 HOH 176 676 298 HOH HOH A . 
F 5 HOH 177 677 106 HOH HOH A . 
F 5 HOH 178 678 62  HOH HOH A . 
F 5 HOH 179 679 232 HOH HOH A . 
F 5 HOH 180 680 156 HOH HOH A . 
F 5 HOH 181 681 196 HOH HOH A . 
F 5 HOH 182 682 238 HOH HOH A . 
F 5 HOH 183 683 39  HOH HOH A . 
F 5 HOH 184 684 122 HOH HOH A . 
F 5 HOH 185 685 78  HOH HOH A . 
F 5 HOH 186 686 17  HOH HOH A . 
F 5 HOH 187 687 267 HOH HOH A . 
F 5 HOH 188 688 80  HOH HOH A . 
F 5 HOH 189 689 301 HOH HOH A . 
F 5 HOH 190 690 258 HOH HOH A . 
F 5 HOH 191 691 102 HOH HOH A . 
F 5 HOH 192 692 281 HOH HOH A . 
F 5 HOH 193 693 249 HOH HOH A . 
F 5 HOH 194 694 144 HOH HOH A . 
F 5 HOH 195 695 221 HOH HOH A . 
F 5 HOH 196 696 299 HOH HOH A . 
F 5 HOH 197 697 188 HOH HOH A . 
F 5 HOH 198 698 169 HOH HOH A . 
F 5 HOH 199 699 97  HOH HOH A . 
F 5 HOH 200 700 108 HOH HOH A . 
F 5 HOH 201 701 37  HOH HOH A . 
F 5 HOH 202 702 297 HOH HOH A . 
F 5 HOH 203 703 19  HOH HOH A . 
F 5 HOH 204 704 161 HOH HOH A . 
F 5 HOH 205 705 56  HOH HOH A . 
F 5 HOH 206 706 290 HOH HOH A . 
F 5 HOH 207 707 336 HOH HOH A . 
F 5 HOH 208 708 175 HOH HOH A . 
F 5 HOH 209 709 300 HOH HOH A . 
F 5 HOH 210 710 11  HOH HOH A . 
F 5 HOH 211 711 276 HOH HOH A . 
F 5 HOH 212 712 284 HOH HOH A . 
F 5 HOH 213 713 85  HOH HOH A . 
F 5 HOH 214 714 305 HOH HOH A . 
F 5 HOH 215 715 248 HOH HOH A . 
F 5 HOH 216 716 225 HOH HOH A . 
F 5 HOH 217 717 177 HOH HOH A . 
F 5 HOH 218 718 128 HOH HOH A . 
F 5 HOH 219 719 313 HOH HOH A . 
F 5 HOH 220 720 179 HOH HOH A . 
F 5 HOH 221 721 47  HOH HOH A . 
F 5 HOH 222 722 214 HOH HOH A . 
F 5 HOH 223 723 35  HOH HOH A . 
F 5 HOH 224 724 203 HOH HOH A . 
F 5 HOH 225 725 307 HOH HOH A . 
F 5 HOH 226 726 288 HOH HOH A . 
F 5 HOH 227 727 180 HOH HOH A . 
F 5 HOH 228 728 254 HOH HOH A . 
F 5 HOH 229 729 330 HOH HOH A . 
F 5 HOH 230 730 302 HOH HOH A . 
F 5 HOH 231 731 183 HOH HOH A . 
F 5 HOH 232 732 292 HOH HOH A . 
F 5 HOH 233 733 172 HOH HOH A . 
F 5 HOH 234 734 162 HOH HOH A . 
F 5 HOH 235 735 234 HOH HOH A . 
F 5 HOH 236 736 160 HOH HOH A . 
F 5 HOH 237 737 129 HOH HOH A . 
F 5 HOH 238 738 231 HOH HOH A . 
F 5 HOH 239 739 1   HOH HOH A . 
F 5 HOH 240 740 246 HOH HOH A . 
F 5 HOH 241 741 167 HOH HOH A . 
F 5 HOH 242 742 268 HOH HOH A . 
F 5 HOH 243 743 324 HOH HOH A . 
F 5 HOH 244 744 334 HOH HOH A . 
F 5 HOH 245 745 269 HOH HOH A . 
F 5 HOH 246 746 90  HOH HOH A . 
F 5 HOH 247 747 312 HOH HOH A . 
F 5 HOH 248 748 319 HOH HOH A . 
F 5 HOH 249 749 155 HOH HOH A . 
F 5 HOH 250 750 337 HOH HOH A . 
F 5 HOH 251 751 255 HOH HOH A . 
F 5 HOH 252 752 186 HOH HOH A . 
F 5 HOH 253 753 314 HOH HOH A . 
F 5 HOH 254 754 315 HOH HOH A . 
F 5 HOH 255 755 306 HOH HOH A . 
F 5 HOH 256 756 280 HOH HOH A . 
F 5 HOH 257 757 285 HOH HOH A . 
F 5 HOH 258 758 250 HOH HOH A . 
F 5 HOH 259 759 138 HOH HOH A . 
F 5 HOH 260 760 325 HOH HOH A . 
F 5 HOH 261 761 176 HOH HOH A . 
F 5 HOH 262 762 251 HOH HOH A . 
F 5 HOH 263 763 170 HOH HOH A . 
F 5 HOH 264 764 235 HOH HOH A . 
F 5 HOH 265 765 148 HOH HOH A . 
F 5 HOH 266 766 127 HOH HOH A . 
F 5 HOH 267 767 181 HOH HOH A . 
F 5 HOH 268 768 286 HOH HOH A . 
F 5 HOH 269 769 46  HOH HOH A . 
F 5 HOH 270 770 224 HOH HOH A . 
F 5 HOH 271 771 256 HOH HOH A . 
F 5 HOH 272 772 133 HOH HOH A . 
F 5 HOH 273 773 322 HOH HOH A . 
F 5 HOH 274 774 163 HOH HOH A . 
F 5 HOH 275 775 308 HOH HOH A . 
F 5 HOH 276 776 247 HOH HOH A . 
F 5 HOH 277 777 244 HOH HOH A . 
F 5 HOH 278 778 212 HOH HOH A . 
F 5 HOH 279 779 310 HOH HOH A . 
F 5 HOH 280 780 261 HOH HOH A . 
F 5 HOH 281 781 87  HOH HOH A . 
F 5 HOH 282 782 216 HOH HOH A . 
F 5 HOH 283 783 320 HOH HOH A . 
F 5 HOH 284 784 277 HOH HOH A . 
F 5 HOH 285 785 296 HOH HOH A . 
F 5 HOH 286 786 318 HOH HOH A . 
F 5 HOH 287 787 139 HOH HOH A . 
F 5 HOH 288 788 89  HOH HOH A . 
F 5 HOH 289 789 236 HOH HOH A . 
F 5 HOH 290 790 333 HOH HOH A . 
F 5 HOH 291 791 126 HOH HOH A . 
F 5 HOH 292 792 295 HOH HOH A . 
F 5 HOH 293 793 278 HOH HOH A . 
F 5 HOH 294 794 304 HOH HOH A . 
F 5 HOH 295 795 202 HOH HOH A . 
F 5 HOH 296 796 328 HOH HOH A . 
F 5 HOH 297 797 241 HOH HOH A . 
F 5 HOH 298 798 205 HOH HOH A . 
F 5 HOH 299 799 257 HOH HOH A . 
F 5 HOH 300 800 199 HOH HOH A . 
F 5 HOH 301 801 194 HOH HOH A . 
F 5 HOH 302 802 145 HOH HOH A . 
F 5 HOH 303 803 200 HOH HOH A . 
F 5 HOH 304 804 71  HOH HOH A . 
F 5 HOH 305 805 64  HOH HOH A . 
F 5 HOH 306 806 107 HOH HOH A . 
F 5 HOH 307 807 209 HOH HOH A . 
F 5 HOH 308 808 329 HOH HOH A . 
F 5 HOH 309 809 165 HOH HOH A . 
F 5 HOH 310 810 215 HOH HOH A . 
F 5 HOH 311 811 217 HOH HOH A . 
F 5 HOH 312 812 294 HOH HOH A . 
F 5 HOH 313 813 273 HOH HOH A . 
G 5 HOH 1   101 229 HOH HOH B . 
G 5 HOH 2   102 190 HOH HOH B . 
G 5 HOH 3   103 332 HOH HOH B . 
G 5 HOH 4   104 52  HOH HOH B . 
G 5 HOH 5   105 23  HOH HOH B . 
G 5 HOH 6   106 112 HOH HOH B . 
G 5 HOH 7   107 132 HOH HOH B . 
G 5 HOH 8   108 103 HOH HOH B . 
G 5 HOH 9   109 111 HOH HOH B . 
G 5 HOH 10  110 113 HOH HOH B . 
G 5 HOH 11  111 20  HOH HOH B . 
G 5 HOH 12  112 110 HOH HOH B . 
G 5 HOH 13  113 316 HOH HOH B . 
G 5 HOH 14  114 275 HOH HOH B . 
G 5 HOH 15  115 282 HOH HOH B . 
G 5 HOH 16  116 189 HOH HOH B . 
G 5 HOH 17  117 151 HOH HOH B . 
G 5 HOH 18  118 326 HOH HOH B . 
G 5 HOH 19  119 311 HOH HOH B . 
G 5 HOH 20  120 115 HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 B DT 14 ? "C5'" ? B DT 20 "C5'" 
2  1 Y 1 B DT 14 ? "C4'" ? B DT 20 "C4'" 
3  1 Y 1 B DT 14 ? "O4'" ? B DT 20 "O4'" 
4  1 Y 1 B DT 14 ? "C3'" ? B DT 20 "C3'" 
5  1 Y 1 B DT 14 ? "O3'" ? B DT 20 "O3'" 
6  1 Y 1 B DT 14 ? "C2'" ? B DT 20 "C2'" 
7  1 Y 1 B DT 14 ? "C1'" ? B DT 20 "C1'" 
8  1 Y 1 B DT 14 ? N1    ? B DT 20 N1    
9  1 Y 1 B DT 14 ? C2    ? B DT 20 C2    
10 1 Y 1 B DT 14 ? O2    ? B DT 20 O2    
11 1 Y 1 B DT 14 ? N3    ? B DT 20 N3    
12 1 Y 1 B DT 14 ? C4    ? B DT 20 C4    
13 1 Y 1 B DT 14 ? O4    ? B DT 20 O4    
14 1 Y 1 B DT 14 ? C5    ? B DT 20 C5    
15 1 Y 1 B DT 14 ? C7    ? B DT 20 C7    
16 1 Y 1 B DT 14 ? C6    ? B DT 20 C6    
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.19.2_4158 1 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           2 
? 'model building'  ? ? ? ? ? ? ? ? ? ? ? Coot   ? ? ? .           3 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .           4 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .           5 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? BOS    ? ? ? .           6 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8TX4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     55.295 
_cell.length_a_esd                 ? 
_cell.length_b                     67.977 
_cell.length_b_esd                 ? 
_cell.length_c                     127.906 
_cell.length_c_esd                 ? 
_cell.volume                       480773.084 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8TX4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8TX4 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.34 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          47.43 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Bis-tris propane pH 7.5, 0.2 M Sodium/Potassium phosphate, 16% PEG3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'ADSC QUANTUM 315r' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-12-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97648 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ALS BEAMLINE 5.0.3' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97648 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   5.0.3 
_diffrn_source.pdbx_synchrotron_site       ALS 
# 
_reflns.B_iso_Wilson_estimate                          25.68 
_reflns.entry_id                                       8TX4 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.90 
_reflns.d_resolution_low                               63.95 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     38683 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.68 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          17.48 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.03001 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   1 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.1056 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.90 
_reflns_shell.d_res_low                                     1.968 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.61 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3806 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               12.6 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.2812 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.917 
_reflns_shell.pdbx_CC_star                                  0.978 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.71 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.9781 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               36.76 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8TX4 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.90 
_refine.ls_d_res_low                             63.95 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     38665 
_refine.ls_number_reflns_R_free                  1888 
_refine.ls_number_reflns_R_work                  36777 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.68 
_refine.ls_percent_reflns_R_free                 4.88 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1767 
_refine.ls_R_factor_R_free                       0.2180 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1747 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 21.3121 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1898 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.90 
_refine_hist.d_res_low                        63.95 
_refine_hist.number_atoms_solvent             333 
_refine_hist.number_atoms_total               3531 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3104 
_refine_hist.pdbx_number_atoms_nucleic_acid   87 
_refine_hist.pdbx_number_atoms_ligand         7 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0058  ? 3308 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.8219  ? 4508 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0529  ? 453  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0071  ? 567  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.0074 ? 451  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.90 1.95  . . 144 2784 99.80  . . . . 0.2651 . . . . . . . . . . . 0.2803 
'X-RAY DIFFRACTION' 1.95 2.01  . . 149 2764 99.66  . . . . 0.2282 . . . . . . . . . . . 0.2682 
'X-RAY DIFFRACTION' 2.01 2.07  . . 149 2784 99.73  . . . . 0.2134 . . . . . . . . . . . 0.2498 
'X-RAY DIFFRACTION' 2.07 2.15  . . 145 2791 99.83  . . . . 0.1952 . . . . . . . . . . . 0.2551 
'X-RAY DIFFRACTION' 2.15 2.23  . . 155 2777 99.76  . . . . 0.1747 . . . . . . . . . . . 0.2320 
'X-RAY DIFFRACTION' 2.23 2.34  . . 162 2810 99.93  . . . . 0.1719 . . . . . . . . . . . 0.2529 
'X-RAY DIFFRACTION' 2.34 2.46  . . 122 2828 99.90  . . . . 0.1803 . . . . . . . . . . . 0.2006 
'X-RAY DIFFRACTION' 2.46 2.61  . . 135 2833 99.97  . . . . 0.1804 . . . . . . . . . . . 0.1996 
'X-RAY DIFFRACTION' 2.61 2.81  . . 132 2842 99.83  . . . . 0.1771 . . . . . . . . . . . 0.2137 
'X-RAY DIFFRACTION' 2.81 3.10  . . 141 2834 99.63  . . . . 0.1796 . . . . . . . . . . . 0.2319 
'X-RAY DIFFRACTION' 3.10 3.55  . . 147 2819 98.83  . . . . 0.1676 . . . . . . . . . . . 0.2225 
'X-RAY DIFFRACTION' 3.55 4.47  . . 145 2905 100.00 . . . . 0.1470 . . . . . . . . . . . 0.1825 
'X-RAY DIFFRACTION' 4.47 63.95 . . 162 3006 99.15  . . . . 0.1681 . . . . . . . . . . . 0.2069 
# 
_struct.entry_id                     8TX4 
_struct.title                        'Crystal Structure of rA3G-ssDNA-GA' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8TX4 
_struct_keywords.text            'DEAMINASE, APOBEC, HYDROLASE, HYDROLASE-DNA COMPLEX' 
_struct_keywords.pdbx_keywords   HYDROLASE/DNA 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 4 ? 
F N N 5 ? 
G N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP M1GSK9_MACMU M1GSK9 ? 1 
;MKPQIRNMVEPMDPRTFVSNFNNRPILSGLDTVWLCCEVKTKDPSGPPLDAKIFQGKVYPKAKYHPEMRFLRWFHKWRQL
HHDQEYKVTWYVSWSPCTRCANSVATFLAKDPKVTLTIFVARLYYFWKPDYQQALRILCQKRDGPHATMKIMNYNEFQDC
WNKFVDGRGKPFKPWNNLPKHYTLLQATLGELLRHLMDPGTFTSNFNNKPWVSGQHETYLCYKVERLHNDTWVPLNQHRG
FLRNQAPNIHGFPKGRHAELCFLDLIPFWKLDGQQYRVTCFTSWSPCFSCAQEMAKFISNNEHVSLCIFAARIYDDQGRY
QEGLRTLHRDGAKIAMMNYSEFEYCWDTFVDRQGRPFQPWDGLDEHSQALSGRLRAILQN
;
1 
2 PDB 8TX4         8TX4   ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8TX4 A 8 ? 383 ? M1GSK9 1  ? 380 ? 1  380 
2 2 8TX4 B 1 ? 22  ? 8TX4   -5 ? 16  ? -5 16  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8TX4 GLY A 1   ? UNP M1GSK9 ?   ?   'expression tag' -6  1  
1 8TX4 PRO A 2   ? UNP M1GSK9 ?   ?   'expression tag' -5  2  
1 8TX4 GLY A 3   ? UNP M1GSK9 ?   ?   'expression tag' -4  3  
1 8TX4 GLY A 4   ? UNP M1GSK9 ?   ?   'expression tag' -3  4  
1 8TX4 SER A 5   ? UNP M1GSK9 ?   ?   'expression tag' -2  5  
1 8TX4 GLY A 6   ? UNP M1GSK9 ?   ?   'expression tag' -1  6  
1 8TX4 GLY A 7   ? UNP M1GSK9 ?   ?   'expression tag' 0   7  
1 8TX4 ALA A 146 ? UNP M1GSK9 CYS 139 conflict         139 8  
1 8TX4 GLU A 147 ? UNP M1GSK9 GLN 140 conflict         140 9  
1 8TX4 ALA A 148 ? UNP M1GSK9 LYS 141 conflict         141 10 
1 8TX4 ?   A ?   ? UNP M1GSK9 ARG 142 deletion         ?   11 
1 8TX4 ?   A ?   ? UNP M1GSK9 ASP 143 deletion         ?   12 
1 8TX4 ?   A ?   ? UNP M1GSK9 GLY 144 deletion         ?   13 
1 8TX4 ?   A ?   ? UNP M1GSK9 PRO 145 deletion         ?   14 
1 8TX4 GLY A 149 ? UNP M1GSK9 HIS 146 conflict         142 15 
1 8TX4 ALA A 262 ? UNP M1GSK9 GLU 259 conflict         259 16 
1 8TX4 ILE A 384 ? UNP M1GSK9 ?   ?   'expression tag' 381 17 
1 8TX4 LEU A 385 ? UNP M1GSK9 ?   ?   'expression tag' 382 18 
1 8TX4 GLN A 386 ? UNP M1GSK9 ?   ?   'expression tag' 383 19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1630  ? 
1 MORE         -90   ? 
1 'SSA (A^2)'  19070 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN A 11  ? VAL A 16  ? GLN A 4   VAL A 9   1 ? 6  
HELX_P HELX_P2  AA2 ASP A 20  ? ASN A 29  ? ASP A 13  ASN A 22  1 ? 10 
HELX_P HELX_P3  AA3 LYS A 68  ? TYR A 71  ? LYS A 61  TYR A 64  5 ? 4  
HELX_P HELX_P4  AA4 HIS A 72  ? LEU A 87  ? HIS A 65  LEU A 80  1 ? 16 
HELX_P HELX_P5  AA5 CYS A 104 ? LYS A 117 ? CYS A 97  LYS A 110 1 ? 14 
HELX_P HELX_P6  AA6 LYS A 135 ? ALA A 148 ? LYS A 128 ALA A 141 1 ? 14 
HELX_P HELX_P7  AA7 ASN A 156 ? VAL A 168 ? ASN A 153 VAL A 165 1 ? 13 
HELX_P HELX_P8  AA8 ASN A 180 ? LEU A 196 ? ASN A 177 LEU A 193 1 ? 17 
HELX_P HELX_P9  AA9 ASP A 201 ? ASN A 210 ? ASP A 198 ASN A 207 1 ? 10 
HELX_P HELX_P10 AB1 HIS A 260 ? TRP A 272 ? HIS A 257 TRP A 269 1 ? 13 
HELX_P HELX_P11 AB2 CYS A 290 ? ASN A 304 ? CYS A 287 ASN A 301 1 ? 15 
HELX_P HELX_P12 AB3 ARG A 322 ? ASP A 333 ? ARG A 319 ASP A 330 1 ? 12 
HELX_P HELX_P13 AB4 ASN A 341 ? VAL A 353 ? ASN A 338 VAL A 350 1 ? 13 
HELX_P HELX_P14 AB5 GLY A 365 ? ASN A 383 ? GLY A 362 ASN A 380 1 ? 19 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A HIS 72  ND1 ? ? ? 1_555 C ZN  . ZN ? ? A HIS 65  A ZN  401 1_555 ? ? ? ? ? ? ? 2.221 ? ? 
metalc2 metalc ? ? A CYS 104 SG  ? ? ? 1_555 C ZN  . ZN ? ? A CYS 97  A ZN  401 1_555 ? ? ? ? ? ? ? 2.294 ? ? 
metalc3 metalc ? ? A CYS 107 SG  ? ? ? 1_555 C ZN  . ZN ? ? A CYS 100 A ZN  401 1_555 ? ? ? ? ? ? ? 2.316 ? ? 
metalc4 metalc ? ? A HIS 260 ND1 ? ? ? 1_555 D ZN  . ZN ? ? A HIS 257 A ZN  402 1_555 ? ? ? ? ? ? ? 2.239 ? ? 
metalc5 metalc ? ? A CYS 290 SG  ? ? ? 1_555 D ZN  . ZN ? ? A CYS 287 A ZN  402 1_555 ? ? ? ? ? ? ? 2.302 ? ? 
metalc6 metalc ? ? A CYS 293 SG  ? ? ? 1_555 D ZN  . ZN ? ? A CYS 290 A ZN  402 1_555 ? ? ? ? ? ? ? 2.282 ? ? 
metalc7 metalc ? ? C ZN  .   ZN  ? ? ? 1_555 F HOH . O  ? ? A ZN  401 A HOH 517 1_555 ? ? ? ? ? ? ? 1.915 ? ? 
metalc8 metalc ? ? D ZN  .   ZN  ? ? ? 1_555 E PO4 . O3 ? ? A ZN  402 A PO4 403 1_555 ? ? ? ? ? ? ? 1.992 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  ND1 ? A HIS 72  ? A HIS 65  ? 1_555 ZN ? C ZN . ? A ZN 401 ? 1_555 SG ? A CYS 104 ? A CYS 97  ? 1_555 109.6 ? 
2  ND1 ? A HIS 72  ? A HIS 65  ? 1_555 ZN ? C ZN . ? A ZN 401 ? 1_555 SG ? A CYS 107 ? A CYS 100 ? 1_555 115.9 ? 
3  SG  ? A CYS 104 ? A CYS 97  ? 1_555 ZN ? C ZN . ? A ZN 401 ? 1_555 SG ? A CYS 107 ? A CYS 100 ? 1_555 114.7 ? 
4  ND1 ? A HIS 72  ? A HIS 65  ? 1_555 ZN ? C ZN . ? A ZN 401 ? 1_555 O  ? F HOH .   ? A HOH 517 ? 1_555 100.0 ? 
5  SG  ? A CYS 104 ? A CYS 97  ? 1_555 ZN ? C ZN . ? A ZN 401 ? 1_555 O  ? F HOH .   ? A HOH 517 ? 1_555 104.1 ? 
6  SG  ? A CYS 107 ? A CYS 100 ? 1_555 ZN ? C ZN . ? A ZN 401 ? 1_555 O  ? F HOH .   ? A HOH 517 ? 1_555 110.9 ? 
7  ND1 ? A HIS 260 ? A HIS 257 ? 1_555 ZN ? D ZN . ? A ZN 402 ? 1_555 SG ? A CYS 290 ? A CYS 287 ? 1_555 106.3 ? 
8  ND1 ? A HIS 260 ? A HIS 257 ? 1_555 ZN ? D ZN . ? A ZN 402 ? 1_555 SG ? A CYS 293 ? A CYS 290 ? 1_555 107.3 ? 
9  SG  ? A CYS 290 ? A CYS 287 ? 1_555 ZN ? D ZN . ? A ZN 402 ? 1_555 SG ? A CYS 293 ? A CYS 290 ? 1_555 113.9 ? 
10 ND1 ? A HIS 260 ? A HIS 257 ? 1_555 ZN ? D ZN . ? A ZN 402 ? 1_555 O3 ? E PO4 .   ? A PO4 403 ? 1_555 111.0 ? 
11 SG  ? A CYS 290 ? A CYS 287 ? 1_555 ZN ? D ZN . ? A ZN 402 ? 1_555 O3 ? E PO4 .   ? A PO4 403 ? 1_555 108.3 ? 
12 SG  ? A CYS 293 ? A CYS 290 ? 1_555 ZN ? D ZN . ? A ZN 402 ? 1_555 O3 ? E PO4 .   ? A PO4 403 ? 1_555 110.1 ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           66 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            59 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    67 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     60 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       11.01 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ASP A 57  ? LYS A 64  ? ASP A 50  LYS A 57  
AA1 2 THR A 39  ? LYS A 47  ? THR A 32  LYS A 40  
AA1 3 TYR A 93  ? TRP A 101 ? TYR A 86  TRP A 94  
AA1 4 VAL A 121 ? ARG A 129 ? VAL A 114 ARG A 122 
AA1 5 THR A 151 ? ILE A 154 ? THR A 148 ILE A 151 
AA2 1 TRP A 235 ? ARG A 246 ? TRP A 232 ARG A 243 
AA2 2 TYR A 222 ? LEU A 230 ? TYR A 219 LEU A 227 
AA2 3 TYR A 279 ? TRP A 287 ? TYR A 276 TRP A 284 
AA2 4 VAL A 307 ? ARG A 315 ? VAL A 304 ARG A 312 
AA2 5 LYS A 336 ? MET A 339 ? LYS A 333 MET A 336 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O PHE A 61  ? O PHE A 54  N LEU A 42  ? N LEU A 35  
AA1 2 3 N CYS A 43  ? N CYS A 36  O TYR A 98  ? O TYR A 91  
AA1 3 4 N VAL A 95  ? N VAL A 88  O THR A 122 ? O THR A 115 
AA1 4 5 N ILE A 125 ? N ILE A 118 O THR A 151 ? O THR A 148 
AA2 1 2 O LEU A 245 ? O LEU A 242 N LEU A 223 ? N LEU A 220 
AA2 2 3 N CYS A 224 ? N CYS A 221 O PHE A 284 ? O PHE A 281 
AA2 3 4 N TYR A 279 ? N TYR A 276 O SER A 308 ? O SER A 305 
AA2 4 5 N ILE A 311 ? N ILE A 308 O LYS A 336 ? O LYS A 333 
# 
_pdbx_entry_details.entry_id                   8TX4 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O B HOH 115 ? ? O B HOH 118 ? ? 2.15 
2 1 O A HOH 773 ? ? O B HOH 113 ? ? 2.15 
3 1 O A HOH 679 ? ? O A HOH 760 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN A 248 ? ? -172.09 130.01 
2 1 GLN A 317 ? ? 58.86   17.60  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
_pdbx_refine_tls.id               1 
_pdbx_refine_tls.pdbx_refine_id   'X-RAY DIFFRACTION' 
_pdbx_refine_tls.details          ? 
_pdbx_refine_tls.method           refined 
_pdbx_refine_tls.origin_x         -8.74778191482 
_pdbx_refine_tls.origin_y         -15.5228538415 
_pdbx_refine_tls.origin_z         30.8028166791 
_pdbx_refine_tls.T[1][1]          0.118323414022 
_pdbx_refine_tls.T[1][1]_esd      ? 
_pdbx_refine_tls.T[1][2]          0.00721961684243 
_pdbx_refine_tls.T[1][2]_esd      ? 
_pdbx_refine_tls.T[1][3]          -0.0259128426327 
_pdbx_refine_tls.T[1][3]_esd      ? 
_pdbx_refine_tls.T[2][2]          0.146175300092 
_pdbx_refine_tls.T[2][2]_esd      ? 
_pdbx_refine_tls.T[2][3]          -0.0151965701759 
_pdbx_refine_tls.T[2][3]_esd      ? 
_pdbx_refine_tls.T[3][3]          0.176874181357 
_pdbx_refine_tls.T[3][3]_esd      ? 
_pdbx_refine_tls.L[1][1]          0.414578324622 
_pdbx_refine_tls.L[1][1]_esd      ? 
_pdbx_refine_tls.L[1][2]          0.0537820368639 
_pdbx_refine_tls.L[1][2]_esd      ? 
_pdbx_refine_tls.L[1][3]          0.019461663246 
_pdbx_refine_tls.L[1][3]_esd      ? 
_pdbx_refine_tls.L[2][2]          1.47096477748 
_pdbx_refine_tls.L[2][2]_esd      ? 
_pdbx_refine_tls.L[2][3]          -0.670707479705 
_pdbx_refine_tls.L[2][3]_esd      ? 
_pdbx_refine_tls.L[3][3]          1.19896365012 
_pdbx_refine_tls.L[3][3]_esd      ? 
_pdbx_refine_tls.S[1][1]          0.017068654386 
_pdbx_refine_tls.S[1][1]_esd      ? 
_pdbx_refine_tls.S[1][2]          0.00915392032949 
_pdbx_refine_tls.S[1][2]_esd      ? 
_pdbx_refine_tls.S[1][3]          0.0090691277309 
_pdbx_refine_tls.S[1][3]_esd      ? 
_pdbx_refine_tls.S[2][1]          -0.136119796894 
_pdbx_refine_tls.S[2][1]_esd      ? 
_pdbx_refine_tls.S[2][2]          0.057004057742 
_pdbx_refine_tls.S[2][2]_esd      ? 
_pdbx_refine_tls.S[2][3]          0.159113300663 
_pdbx_refine_tls.S[2][3]_esd      ? 
_pdbx_refine_tls.S[3][1]          0.139529760142 
_pdbx_refine_tls.S[3][1]_esd      ? 
_pdbx_refine_tls.S[3][2]          -0.0907652260452 
_pdbx_refine_tls.S[3][2]_esd      ? 
_pdbx_refine_tls.S[3][3]          -0.0321211730159 
_pdbx_refine_tls.S[3][3]_esd      ? 
# 
_pdbx_refine_tls_group.id                  1 
_pdbx_refine_tls_group.pdbx_refine_id      'X-RAY DIFFRACTION' 
_pdbx_refine_tls_group.refine_tls_id       1 
_pdbx_refine_tls_group.beg_label_asym_id   A 
_pdbx_refine_tls_group.beg_label_seq_id    1 
_pdbx_refine_tls_group.beg_auth_asym_id    A 
_pdbx_refine_tls_group.beg_auth_seq_id     4 
_pdbx_refine_tls_group.beg_PDB_ins_code    ? 
_pdbx_refine_tls_group.end_label_asym_id   F 
_pdbx_refine_tls_group.end_label_seq_id    ? 
_pdbx_refine_tls_group.end_auth_asym_id    S 
_pdbx_refine_tls_group.end_auth_seq_id     337 
_pdbx_refine_tls_group.end_PDB_ins_code    ? 
_pdbx_refine_tls_group.selection           ? 
_pdbx_refine_tls_group.selection_details   all 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY -6  ? A GLY 1   
2  1 Y 1 A PRO -5  ? A PRO 2   
3  1 Y 1 A GLY -4  ? A GLY 3   
4  1 Y 1 A GLY -3  ? A GLY 4   
5  1 Y 1 A SER -2  ? A SER 5   
6  1 Y 1 A GLY -1  ? A GLY 6   
7  1 Y 1 A GLY 0   ? A GLY 7   
8  1 Y 1 A MET 1   ? A MET 8   
9  1 Y 1 A LYS 2   ? A LYS 9   
10 1 Y 1 A PRO 3   ? A PRO 10  
11 1 Y 1 A ILE 381 ? A ILE 384 
12 1 Y 1 A LEU 382 ? A LEU 385 
13 1 Y 1 A GLN 383 ? A GLN 386 
14 1 Y 1 B DT  -5  ? B DT  1   
15 1 Y 1 B DT  -4  ? B DT  2   
16 1 Y 1 B DT  -3  ? B DT  3   
17 1 Y 1 B DC  -2  ? B DC  4   
18 1 Y 1 B DC  -1  ? B DC  5   
19 1 Y 1 B DC  0   ? B DC  6   
20 1 Y 1 B DT  1   ? B DT  7   
21 1 Y 1 B DT  2   ? B DT  8   
22 1 Y 1 B DT  3   ? B DT  9   
23 1 Y 1 B DT  4   ? B DT  10  
24 1 Y 1 B DT  5   ? B DT  11  
25 1 Y 1 B DT  6   ? B DT  12  
26 1 Y 1 B DT  7   ? B DT  13  
27 1 Y 1 B DT  8   ? B DT  14  
28 1 Y 1 B DT  9   ? B DT  15  
29 1 Y 1 B DT  15  ? B DT  21  
30 1 Y 1 B DT  16  ? B DT  22  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
CYS N      N  N N 74  
CYS CA     C  N R 75  
CYS C      C  N N 76  
CYS O      O  N N 77  
CYS CB     C  N N 78  
CYS SG     S  N N 79  
CYS OXT    O  N N 80  
CYS H      H  N N 81  
CYS H2     H  N N 82  
CYS HA     H  N N 83  
CYS HB2    H  N N 84  
CYS HB3    H  N N 85  
CYS HG     H  N N 86  
CYS HXT    H  N N 87  
DA  OP3    O  N N 88  
DA  P      P  N N 89  
DA  OP1    O  N N 90  
DA  OP2    O  N N 91  
DA  "O5'"  O  N N 92  
DA  "C5'"  C  N N 93  
DA  "C4'"  C  N R 94  
DA  "O4'"  O  N N 95  
DA  "C3'"  C  N S 96  
DA  "O3'"  O  N N 97  
DA  "C2'"  C  N N 98  
DA  "C1'"  C  N R 99  
DA  N9     N  Y N 100 
DA  C8     C  Y N 101 
DA  N7     N  Y N 102 
DA  C5     C  Y N 103 
DA  C6     C  Y N 104 
DA  N6     N  N N 105 
DA  N1     N  Y N 106 
DA  C2     C  Y N 107 
DA  N3     N  Y N 108 
DA  C4     C  Y N 109 
DA  HOP3   H  N N 110 
DA  HOP2   H  N N 111 
DA  "H5'"  H  N N 112 
DA  "H5''" H  N N 113 
DA  "H4'"  H  N N 114 
DA  "H3'"  H  N N 115 
DA  "HO3'" H  N N 116 
DA  "H2'"  H  N N 117 
DA  "H2''" H  N N 118 
DA  "H1'"  H  N N 119 
DA  H8     H  N N 120 
DA  H61    H  N N 121 
DA  H62    H  N N 122 
DA  H2     H  N N 123 
DC  OP3    O  N N 124 
DC  P      P  N N 125 
DC  OP1    O  N N 126 
DC  OP2    O  N N 127 
DC  "O5'"  O  N N 128 
DC  "C5'"  C  N N 129 
DC  "C4'"  C  N R 130 
DC  "O4'"  O  N N 131 
DC  "C3'"  C  N S 132 
DC  "O3'"  O  N N 133 
DC  "C2'"  C  N N 134 
DC  "C1'"  C  N R 135 
DC  N1     N  N N 136 
DC  C2     C  N N 137 
DC  O2     O  N N 138 
DC  N3     N  N N 139 
DC  C4     C  N N 140 
DC  N4     N  N N 141 
DC  C5     C  N N 142 
DC  C6     C  N N 143 
DC  HOP3   H  N N 144 
DC  HOP2   H  N N 145 
DC  "H5'"  H  N N 146 
DC  "H5''" H  N N 147 
DC  "H4'"  H  N N 148 
DC  "H3'"  H  N N 149 
DC  "HO3'" H  N N 150 
DC  "H2'"  H  N N 151 
DC  "H2''" H  N N 152 
DC  "H1'"  H  N N 153 
DC  H41    H  N N 154 
DC  H42    H  N N 155 
DC  H5     H  N N 156 
DC  H6     H  N N 157 
DG  OP3    O  N N 158 
DG  P      P  N N 159 
DG  OP1    O  N N 160 
DG  OP2    O  N N 161 
DG  "O5'"  O  N N 162 
DG  "C5'"  C  N N 163 
DG  "C4'"  C  N R 164 
DG  "O4'"  O  N N 165 
DG  "C3'"  C  N S 166 
DG  "O3'"  O  N N 167 
DG  "C2'"  C  N N 168 
DG  "C1'"  C  N R 169 
DG  N9     N  Y N 170 
DG  C8     C  Y N 171 
DG  N7     N  Y N 172 
DG  C5     C  Y N 173 
DG  C6     C  N N 174 
DG  O6     O  N N 175 
DG  N1     N  N N 176 
DG  C2     C  N N 177 
DG  N2     N  N N 178 
DG  N3     N  N N 179 
DG  C4     C  Y N 180 
DG  HOP3   H  N N 181 
DG  HOP2   H  N N 182 
DG  "H5'"  H  N N 183 
DG  "H5''" H  N N 184 
DG  "H4'"  H  N N 185 
DG  "H3'"  H  N N 186 
DG  "HO3'" H  N N 187 
DG  "H2'"  H  N N 188 
DG  "H2''" H  N N 189 
DG  "H1'"  H  N N 190 
DG  H8     H  N N 191 
DG  H1     H  N N 192 
DG  H21    H  N N 193 
DG  H22    H  N N 194 
DT  OP3    O  N N 195 
DT  P      P  N N 196 
DT  OP1    O  N N 197 
DT  OP2    O  N N 198 
DT  "O5'"  O  N N 199 
DT  "C5'"  C  N N 200 
DT  "C4'"  C  N R 201 
DT  "O4'"  O  N N 202 
DT  "C3'"  C  N S 203 
DT  "O3'"  O  N N 204 
DT  "C2'"  C  N N 205 
DT  "C1'"  C  N R 206 
DT  N1     N  N N 207 
DT  C2     C  N N 208 
DT  O2     O  N N 209 
DT  N3     N  N N 210 
DT  C4     C  N N 211 
DT  O4     O  N N 212 
DT  C5     C  N N 213 
DT  C7     C  N N 214 
DT  C6     C  N N 215 
DT  HOP3   H  N N 216 
DT  HOP2   H  N N 217 
DT  "H5'"  H  N N 218 
DT  "H5''" H  N N 219 
DT  "H4'"  H  N N 220 
DT  "H3'"  H  N N 221 
DT  "HO3'" H  N N 222 
DT  "H2'"  H  N N 223 
DT  "H2''" H  N N 224 
DT  "H1'"  H  N N 225 
DT  H3     H  N N 226 
DT  H71    H  N N 227 
DT  H72    H  N N 228 
DT  H73    H  N N 229 
DT  H6     H  N N 230 
GLN N      N  N N 231 
GLN CA     C  N S 232 
GLN C      C  N N 233 
GLN O      O  N N 234 
GLN CB     C  N N 235 
GLN CG     C  N N 236 
GLN CD     C  N N 237 
GLN OE1    O  N N 238 
GLN NE2    N  N N 239 
GLN OXT    O  N N 240 
GLN H      H  N N 241 
GLN H2     H  N N 242 
GLN HA     H  N N 243 
GLN HB2    H  N N 244 
GLN HB3    H  N N 245 
GLN HG2    H  N N 246 
GLN HG3    H  N N 247 
GLN HE21   H  N N 248 
GLN HE22   H  N N 249 
GLN HXT    H  N N 250 
GLU N      N  N N 251 
GLU CA     C  N S 252 
GLU C      C  N N 253 
GLU O      O  N N 254 
GLU CB     C  N N 255 
GLU CG     C  N N 256 
GLU CD     C  N N 257 
GLU OE1    O  N N 258 
GLU OE2    O  N N 259 
GLU OXT    O  N N 260 
GLU H      H  N N 261 
GLU H2     H  N N 262 
GLU HA     H  N N 263 
GLU HB2    H  N N 264 
GLU HB3    H  N N 265 
GLU HG2    H  N N 266 
GLU HG3    H  N N 267 
GLU HE2    H  N N 268 
GLU HXT    H  N N 269 
GLY N      N  N N 270 
GLY CA     C  N N 271 
GLY C      C  N N 272 
GLY O      O  N N 273 
GLY OXT    O  N N 274 
GLY H      H  N N 275 
GLY H2     H  N N 276 
GLY HA2    H  N N 277 
GLY HA3    H  N N 278 
GLY HXT    H  N N 279 
HIS N      N  N N 280 
HIS CA     C  N S 281 
HIS C      C  N N 282 
HIS O      O  N N 283 
HIS CB     C  N N 284 
HIS CG     C  Y N 285 
HIS ND1    N  Y N 286 
HIS CD2    C  Y N 287 
HIS CE1    C  Y N 288 
HIS NE2    N  Y N 289 
HIS OXT    O  N N 290 
HIS H      H  N N 291 
HIS H2     H  N N 292 
HIS HA     H  N N 293 
HIS HB2    H  N N 294 
HIS HB3    H  N N 295 
HIS HD1    H  N N 296 
HIS HD2    H  N N 297 
HIS HE1    H  N N 298 
HIS HE2    H  N N 299 
HIS HXT    H  N N 300 
HOH O      O  N N 301 
HOH H1     H  N N 302 
HOH H2     H  N N 303 
ILE N      N  N N 304 
ILE CA     C  N S 305 
ILE C      C  N N 306 
ILE O      O  N N 307 
ILE CB     C  N S 308 
ILE CG1    C  N N 309 
ILE CG2    C  N N 310 
ILE CD1    C  N N 311 
ILE OXT    O  N N 312 
ILE H      H  N N 313 
ILE H2     H  N N 314 
ILE HA     H  N N 315 
ILE HB     H  N N 316 
ILE HG12   H  N N 317 
ILE HG13   H  N N 318 
ILE HG21   H  N N 319 
ILE HG22   H  N N 320 
ILE HG23   H  N N 321 
ILE HD11   H  N N 322 
ILE HD12   H  N N 323 
ILE HD13   H  N N 324 
ILE HXT    H  N N 325 
LEU N      N  N N 326 
LEU CA     C  N S 327 
LEU C      C  N N 328 
LEU O      O  N N 329 
LEU CB     C  N N 330 
LEU CG     C  N N 331 
LEU CD1    C  N N 332 
LEU CD2    C  N N 333 
LEU OXT    O  N N 334 
LEU H      H  N N 335 
LEU H2     H  N N 336 
LEU HA     H  N N 337 
LEU HB2    H  N N 338 
LEU HB3    H  N N 339 
LEU HG     H  N N 340 
LEU HD11   H  N N 341 
LEU HD12   H  N N 342 
LEU HD13   H  N N 343 
LEU HD21   H  N N 344 
LEU HD22   H  N N 345 
LEU HD23   H  N N 346 
LEU HXT    H  N N 347 
LYS N      N  N N 348 
LYS CA     C  N S 349 
LYS C      C  N N 350 
LYS O      O  N N 351 
LYS CB     C  N N 352 
LYS CG     C  N N 353 
LYS CD     C  N N 354 
LYS CE     C  N N 355 
LYS NZ     N  N N 356 
LYS OXT    O  N N 357 
LYS H      H  N N 358 
LYS H2     H  N N 359 
LYS HA     H  N N 360 
LYS HB2    H  N N 361 
LYS HB3    H  N N 362 
LYS HG2    H  N N 363 
LYS HG3    H  N N 364 
LYS HD2    H  N N 365 
LYS HD3    H  N N 366 
LYS HE2    H  N N 367 
LYS HE3    H  N N 368 
LYS HZ1    H  N N 369 
LYS HZ2    H  N N 370 
LYS HZ3    H  N N 371 
LYS HXT    H  N N 372 
MET N      N  N N 373 
MET CA     C  N S 374 
MET C      C  N N 375 
MET O      O  N N 376 
MET CB     C  N N 377 
MET CG     C  N N 378 
MET SD     S  N N 379 
MET CE     C  N N 380 
MET OXT    O  N N 381 
MET H      H  N N 382 
MET H2     H  N N 383 
MET HA     H  N N 384 
MET HB2    H  N N 385 
MET HB3    H  N N 386 
MET HG2    H  N N 387 
MET HG3    H  N N 388 
MET HE1    H  N N 389 
MET HE2    H  N N 390 
MET HE3    H  N N 391 
MET HXT    H  N N 392 
PHE N      N  N N 393 
PHE CA     C  N S 394 
PHE C      C  N N 395 
PHE O      O  N N 396 
PHE CB     C  N N 397 
PHE CG     C  Y N 398 
PHE CD1    C  Y N 399 
PHE CD2    C  Y N 400 
PHE CE1    C  Y N 401 
PHE CE2    C  Y N 402 
PHE CZ     C  Y N 403 
PHE OXT    O  N N 404 
PHE H      H  N N 405 
PHE H2     H  N N 406 
PHE HA     H  N N 407 
PHE HB2    H  N N 408 
PHE HB3    H  N N 409 
PHE HD1    H  N N 410 
PHE HD2    H  N N 411 
PHE HE1    H  N N 412 
PHE HE2    H  N N 413 
PHE HZ     H  N N 414 
PHE HXT    H  N N 415 
PO4 P      P  N N 416 
PO4 O1     O  N N 417 
PO4 O2     O  N N 418 
PO4 O3     O  N N 419 
PO4 O4     O  N N 420 
PRO N      N  N N 421 
PRO CA     C  N S 422 
PRO C      C  N N 423 
PRO O      O  N N 424 
PRO CB     C  N N 425 
PRO CG     C  N N 426 
PRO CD     C  N N 427 
PRO OXT    O  N N 428 
PRO H      H  N N 429 
PRO HA     H  N N 430 
PRO HB2    H  N N 431 
PRO HB3    H  N N 432 
PRO HG2    H  N N 433 
PRO HG3    H  N N 434 
PRO HD2    H  N N 435 
PRO HD3    H  N N 436 
PRO HXT    H  N N 437 
SER N      N  N N 438 
SER CA     C  N S 439 
SER C      C  N N 440 
SER O      O  N N 441 
SER CB     C  N N 442 
SER OG     O  N N 443 
SER OXT    O  N N 444 
SER H      H  N N 445 
SER H2     H  N N 446 
SER HA     H  N N 447 
SER HB2    H  N N 448 
SER HB3    H  N N 449 
SER HG     H  N N 450 
SER HXT    H  N N 451 
THR N      N  N N 452 
THR CA     C  N S 453 
THR C      C  N N 454 
THR O      O  N N 455 
THR CB     C  N R 456 
THR OG1    O  N N 457 
THR CG2    C  N N 458 
THR OXT    O  N N 459 
THR H      H  N N 460 
THR H2     H  N N 461 
THR HA     H  N N 462 
THR HB     H  N N 463 
THR HG1    H  N N 464 
THR HG21   H  N N 465 
THR HG22   H  N N 466 
THR HG23   H  N N 467 
THR HXT    H  N N 468 
TRP N      N  N N 469 
TRP CA     C  N S 470 
TRP C      C  N N 471 
TRP O      O  N N 472 
TRP CB     C  N N 473 
TRP CG     C  Y N 474 
TRP CD1    C  Y N 475 
TRP CD2    C  Y N 476 
TRP NE1    N  Y N 477 
TRP CE2    C  Y N 478 
TRP CE3    C  Y N 479 
TRP CZ2    C  Y N 480 
TRP CZ3    C  Y N 481 
TRP CH2    C  Y N 482 
TRP OXT    O  N N 483 
TRP H      H  N N 484 
TRP H2     H  N N 485 
TRP HA     H  N N 486 
TRP HB2    H  N N 487 
TRP HB3    H  N N 488 
TRP HD1    H  N N 489 
TRP HE1    H  N N 490 
TRP HE3    H  N N 491 
TRP HZ2    H  N N 492 
TRP HZ3    H  N N 493 
TRP HH2    H  N N 494 
TRP HXT    H  N N 495 
TYR N      N  N N 496 
TYR CA     C  N S 497 
TYR C      C  N N 498 
TYR O      O  N N 499 
TYR CB     C  N N 500 
TYR CG     C  Y N 501 
TYR CD1    C  Y N 502 
TYR CD2    C  Y N 503 
TYR CE1    C  Y N 504 
TYR CE2    C  Y N 505 
TYR CZ     C  Y N 506 
TYR OH     O  N N 507 
TYR OXT    O  N N 508 
TYR H      H  N N 509 
TYR H2     H  N N 510 
TYR HA     H  N N 511 
TYR HB2    H  N N 512 
TYR HB3    H  N N 513 
TYR HD1    H  N N 514 
TYR HD2    H  N N 515 
TYR HE1    H  N N 516 
TYR HE2    H  N N 517 
TYR HH     H  N N 518 
TYR HXT    H  N N 519 
VAL N      N  N N 520 
VAL CA     C  N S 521 
VAL C      C  N N 522 
VAL O      O  N N 523 
VAL CB     C  N N 524 
VAL CG1    C  N N 525 
VAL CG2    C  N N 526 
VAL OXT    O  N N 527 
VAL H      H  N N 528 
VAL H2     H  N N 529 
VAL HA     H  N N 530 
VAL HB     H  N N 531 
VAL HG11   H  N N 532 
VAL HG12   H  N N 533 
VAL HG13   H  N N 534 
VAL HG21   H  N N 535 
VAL HG22   H  N N 536 
VAL HG23   H  N N 537 
VAL HXT    H  N N 538 
ZN  ZN     ZN N N 539 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
DA  OP3   P      sing N N 83  
DA  OP3   HOP3   sing N N 84  
DA  P     OP1    doub N N 85  
DA  P     OP2    sing N N 86  
DA  P     "O5'"  sing N N 87  
DA  OP2   HOP2   sing N N 88  
DA  "O5'" "C5'"  sing N N 89  
DA  "C5'" "C4'"  sing N N 90  
DA  "C5'" "H5'"  sing N N 91  
DA  "C5'" "H5''" sing N N 92  
DA  "C4'" "O4'"  sing N N 93  
DA  "C4'" "C3'"  sing N N 94  
DA  "C4'" "H4'"  sing N N 95  
DA  "O4'" "C1'"  sing N N 96  
DA  "C3'" "O3'"  sing N N 97  
DA  "C3'" "C2'"  sing N N 98  
DA  "C3'" "H3'"  sing N N 99  
DA  "O3'" "HO3'" sing N N 100 
DA  "C2'" "C1'"  sing N N 101 
DA  "C2'" "H2'"  sing N N 102 
DA  "C2'" "H2''" sing N N 103 
DA  "C1'" N9     sing N N 104 
DA  "C1'" "H1'"  sing N N 105 
DA  N9    C8     sing Y N 106 
DA  N9    C4     sing Y N 107 
DA  C8    N7     doub Y N 108 
DA  C8    H8     sing N N 109 
DA  N7    C5     sing Y N 110 
DA  C5    C6     sing Y N 111 
DA  C5    C4     doub Y N 112 
DA  C6    N6     sing N N 113 
DA  C6    N1     doub Y N 114 
DA  N6    H61    sing N N 115 
DA  N6    H62    sing N N 116 
DA  N1    C2     sing Y N 117 
DA  C2    N3     doub Y N 118 
DA  C2    H2     sing N N 119 
DA  N3    C4     sing Y N 120 
DC  OP3   P      sing N N 121 
DC  OP3   HOP3   sing N N 122 
DC  P     OP1    doub N N 123 
DC  P     OP2    sing N N 124 
DC  P     "O5'"  sing N N 125 
DC  OP2   HOP2   sing N N 126 
DC  "O5'" "C5'"  sing N N 127 
DC  "C5'" "C4'"  sing N N 128 
DC  "C5'" "H5'"  sing N N 129 
DC  "C5'" "H5''" sing N N 130 
DC  "C4'" "O4'"  sing N N 131 
DC  "C4'" "C3'"  sing N N 132 
DC  "C4'" "H4'"  sing N N 133 
DC  "O4'" "C1'"  sing N N 134 
DC  "C3'" "O3'"  sing N N 135 
DC  "C3'" "C2'"  sing N N 136 
DC  "C3'" "H3'"  sing N N 137 
DC  "O3'" "HO3'" sing N N 138 
DC  "C2'" "C1'"  sing N N 139 
DC  "C2'" "H2'"  sing N N 140 
DC  "C2'" "H2''" sing N N 141 
DC  "C1'" N1     sing N N 142 
DC  "C1'" "H1'"  sing N N 143 
DC  N1    C2     sing N N 144 
DC  N1    C6     sing N N 145 
DC  C2    O2     doub N N 146 
DC  C2    N3     sing N N 147 
DC  N3    C4     doub N N 148 
DC  C4    N4     sing N N 149 
DC  C4    C5     sing N N 150 
DC  N4    H41    sing N N 151 
DC  N4    H42    sing N N 152 
DC  C5    C6     doub N N 153 
DC  C5    H5     sing N N 154 
DC  C6    H6     sing N N 155 
DG  OP3   P      sing N N 156 
DG  OP3   HOP3   sing N N 157 
DG  P     OP1    doub N N 158 
DG  P     OP2    sing N N 159 
DG  P     "O5'"  sing N N 160 
DG  OP2   HOP2   sing N N 161 
DG  "O5'" "C5'"  sing N N 162 
DG  "C5'" "C4'"  sing N N 163 
DG  "C5'" "H5'"  sing N N 164 
DG  "C5'" "H5''" sing N N 165 
DG  "C4'" "O4'"  sing N N 166 
DG  "C4'" "C3'"  sing N N 167 
DG  "C4'" "H4'"  sing N N 168 
DG  "O4'" "C1'"  sing N N 169 
DG  "C3'" "O3'"  sing N N 170 
DG  "C3'" "C2'"  sing N N 171 
DG  "C3'" "H3'"  sing N N 172 
DG  "O3'" "HO3'" sing N N 173 
DG  "C2'" "C1'"  sing N N 174 
DG  "C2'" "H2'"  sing N N 175 
DG  "C2'" "H2''" sing N N 176 
DG  "C1'" N9     sing N N 177 
DG  "C1'" "H1'"  sing N N 178 
DG  N9    C8     sing Y N 179 
DG  N9    C4     sing Y N 180 
DG  C8    N7     doub Y N 181 
DG  C8    H8     sing N N 182 
DG  N7    C5     sing Y N 183 
DG  C5    C6     sing N N 184 
DG  C5    C4     doub Y N 185 
DG  C6    O6     doub N N 186 
DG  C6    N1     sing N N 187 
DG  N1    C2     sing N N 188 
DG  N1    H1     sing N N 189 
DG  C2    N2     sing N N 190 
DG  C2    N3     doub N N 191 
DG  N2    H21    sing N N 192 
DG  N2    H22    sing N N 193 
DG  N3    C4     sing N N 194 
DT  OP3   P      sing N N 195 
DT  OP3   HOP3   sing N N 196 
DT  P     OP1    doub N N 197 
DT  P     OP2    sing N N 198 
DT  P     "O5'"  sing N N 199 
DT  OP2   HOP2   sing N N 200 
DT  "O5'" "C5'"  sing N N 201 
DT  "C5'" "C4'"  sing N N 202 
DT  "C5'" "H5'"  sing N N 203 
DT  "C5'" "H5''" sing N N 204 
DT  "C4'" "O4'"  sing N N 205 
DT  "C4'" "C3'"  sing N N 206 
DT  "C4'" "H4'"  sing N N 207 
DT  "O4'" "C1'"  sing N N 208 
DT  "C3'" "O3'"  sing N N 209 
DT  "C3'" "C2'"  sing N N 210 
DT  "C3'" "H3'"  sing N N 211 
DT  "O3'" "HO3'" sing N N 212 
DT  "C2'" "C1'"  sing N N 213 
DT  "C2'" "H2'"  sing N N 214 
DT  "C2'" "H2''" sing N N 215 
DT  "C1'" N1     sing N N 216 
DT  "C1'" "H1'"  sing N N 217 
DT  N1    C2     sing N N 218 
DT  N1    C6     sing N N 219 
DT  C2    O2     doub N N 220 
DT  C2    N3     sing N N 221 
DT  N3    C4     sing N N 222 
DT  N3    H3     sing N N 223 
DT  C4    O4     doub N N 224 
DT  C4    C5     sing N N 225 
DT  C5    C7     sing N N 226 
DT  C5    C6     doub N N 227 
DT  C7    H71    sing N N 228 
DT  C7    H72    sing N N 229 
DT  C7    H73    sing N N 230 
DT  C6    H6     sing N N 231 
GLN N     CA     sing N N 232 
GLN N     H      sing N N 233 
GLN N     H2     sing N N 234 
GLN CA    C      sing N N 235 
GLN CA    CB     sing N N 236 
GLN CA    HA     sing N N 237 
GLN C     O      doub N N 238 
GLN C     OXT    sing N N 239 
GLN CB    CG     sing N N 240 
GLN CB    HB2    sing N N 241 
GLN CB    HB3    sing N N 242 
GLN CG    CD     sing N N 243 
GLN CG    HG2    sing N N 244 
GLN CG    HG3    sing N N 245 
GLN CD    OE1    doub N N 246 
GLN CD    NE2    sing N N 247 
GLN NE2   HE21   sing N N 248 
GLN NE2   HE22   sing N N 249 
GLN OXT   HXT    sing N N 250 
GLU N     CA     sing N N 251 
GLU N     H      sing N N 252 
GLU N     H2     sing N N 253 
GLU CA    C      sing N N 254 
GLU CA    CB     sing N N 255 
GLU CA    HA     sing N N 256 
GLU C     O      doub N N 257 
GLU C     OXT    sing N N 258 
GLU CB    CG     sing N N 259 
GLU CB    HB2    sing N N 260 
GLU CB    HB3    sing N N 261 
GLU CG    CD     sing N N 262 
GLU CG    HG2    sing N N 263 
GLU CG    HG3    sing N N 264 
GLU CD    OE1    doub N N 265 
GLU CD    OE2    sing N N 266 
GLU OE2   HE2    sing N N 267 
GLU OXT   HXT    sing N N 268 
GLY N     CA     sing N N 269 
GLY N     H      sing N N 270 
GLY N     H2     sing N N 271 
GLY CA    C      sing N N 272 
GLY CA    HA2    sing N N 273 
GLY CA    HA3    sing N N 274 
GLY C     O      doub N N 275 
GLY C     OXT    sing N N 276 
GLY OXT   HXT    sing N N 277 
HIS N     CA     sing N N 278 
HIS N     H      sing N N 279 
HIS N     H2     sing N N 280 
HIS CA    C      sing N N 281 
HIS CA    CB     sing N N 282 
HIS CA    HA     sing N N 283 
HIS C     O      doub N N 284 
HIS C     OXT    sing N N 285 
HIS CB    CG     sing N N 286 
HIS CB    HB2    sing N N 287 
HIS CB    HB3    sing N N 288 
HIS CG    ND1    sing Y N 289 
HIS CG    CD2    doub Y N 290 
HIS ND1   CE1    doub Y N 291 
HIS ND1   HD1    sing N N 292 
HIS CD2   NE2    sing Y N 293 
HIS CD2   HD2    sing N N 294 
HIS CE1   NE2    sing Y N 295 
HIS CE1   HE1    sing N N 296 
HIS NE2   HE2    sing N N 297 
HIS OXT   HXT    sing N N 298 
HOH O     H1     sing N N 299 
HOH O     H2     sing N N 300 
ILE N     CA     sing N N 301 
ILE N     H      sing N N 302 
ILE N     H2     sing N N 303 
ILE CA    C      sing N N 304 
ILE CA    CB     sing N N 305 
ILE CA    HA     sing N N 306 
ILE C     O      doub N N 307 
ILE C     OXT    sing N N 308 
ILE CB    CG1    sing N N 309 
ILE CB    CG2    sing N N 310 
ILE CB    HB     sing N N 311 
ILE CG1   CD1    sing N N 312 
ILE CG1   HG12   sing N N 313 
ILE CG1   HG13   sing N N 314 
ILE CG2   HG21   sing N N 315 
ILE CG2   HG22   sing N N 316 
ILE CG2   HG23   sing N N 317 
ILE CD1   HD11   sing N N 318 
ILE CD1   HD12   sing N N 319 
ILE CD1   HD13   sing N N 320 
ILE OXT   HXT    sing N N 321 
LEU N     CA     sing N N 322 
LEU N     H      sing N N 323 
LEU N     H2     sing N N 324 
LEU CA    C      sing N N 325 
LEU CA    CB     sing N N 326 
LEU CA    HA     sing N N 327 
LEU C     O      doub N N 328 
LEU C     OXT    sing N N 329 
LEU CB    CG     sing N N 330 
LEU CB    HB2    sing N N 331 
LEU CB    HB3    sing N N 332 
LEU CG    CD1    sing N N 333 
LEU CG    CD2    sing N N 334 
LEU CG    HG     sing N N 335 
LEU CD1   HD11   sing N N 336 
LEU CD1   HD12   sing N N 337 
LEU CD1   HD13   sing N N 338 
LEU CD2   HD21   sing N N 339 
LEU CD2   HD22   sing N N 340 
LEU CD2   HD23   sing N N 341 
LEU OXT   HXT    sing N N 342 
LYS N     CA     sing N N 343 
LYS N     H      sing N N 344 
LYS N     H2     sing N N 345 
LYS CA    C      sing N N 346 
LYS CA    CB     sing N N 347 
LYS CA    HA     sing N N 348 
LYS C     O      doub N N 349 
LYS C     OXT    sing N N 350 
LYS CB    CG     sing N N 351 
LYS CB    HB2    sing N N 352 
LYS CB    HB3    sing N N 353 
LYS CG    CD     sing N N 354 
LYS CG    HG2    sing N N 355 
LYS CG    HG3    sing N N 356 
LYS CD    CE     sing N N 357 
LYS CD    HD2    sing N N 358 
LYS CD    HD3    sing N N 359 
LYS CE    NZ     sing N N 360 
LYS CE    HE2    sing N N 361 
LYS CE    HE3    sing N N 362 
LYS NZ    HZ1    sing N N 363 
LYS NZ    HZ2    sing N N 364 
LYS NZ    HZ3    sing N N 365 
LYS OXT   HXT    sing N N 366 
MET N     CA     sing N N 367 
MET N     H      sing N N 368 
MET N     H2     sing N N 369 
MET CA    C      sing N N 370 
MET CA    CB     sing N N 371 
MET CA    HA     sing N N 372 
MET C     O      doub N N 373 
MET C     OXT    sing N N 374 
MET CB    CG     sing N N 375 
MET CB    HB2    sing N N 376 
MET CB    HB3    sing N N 377 
MET CG    SD     sing N N 378 
MET CG    HG2    sing N N 379 
MET CG    HG3    sing N N 380 
MET SD    CE     sing N N 381 
MET CE    HE1    sing N N 382 
MET CE    HE2    sing N N 383 
MET CE    HE3    sing N N 384 
MET OXT   HXT    sing N N 385 
PHE N     CA     sing N N 386 
PHE N     H      sing N N 387 
PHE N     H2     sing N N 388 
PHE CA    C      sing N N 389 
PHE CA    CB     sing N N 390 
PHE CA    HA     sing N N 391 
PHE C     O      doub N N 392 
PHE C     OXT    sing N N 393 
PHE CB    CG     sing N N 394 
PHE CB    HB2    sing N N 395 
PHE CB    HB3    sing N N 396 
PHE CG    CD1    doub Y N 397 
PHE CG    CD2    sing Y N 398 
PHE CD1   CE1    sing Y N 399 
PHE CD1   HD1    sing N N 400 
PHE CD2   CE2    doub Y N 401 
PHE CD2   HD2    sing N N 402 
PHE CE1   CZ     doub Y N 403 
PHE CE1   HE1    sing N N 404 
PHE CE2   CZ     sing Y N 405 
PHE CE2   HE2    sing N N 406 
PHE CZ    HZ     sing N N 407 
PHE OXT   HXT    sing N N 408 
PO4 P     O1     doub N N 409 
PO4 P     O2     sing N N 410 
PO4 P     O3     sing N N 411 
PO4 P     O4     sing N N 412 
PRO N     CA     sing N N 413 
PRO N     CD     sing N N 414 
PRO N     H      sing N N 415 
PRO CA    C      sing N N 416 
PRO CA    CB     sing N N 417 
PRO CA    HA     sing N N 418 
PRO C     O      doub N N 419 
PRO C     OXT    sing N N 420 
PRO CB    CG     sing N N 421 
PRO CB    HB2    sing N N 422 
PRO CB    HB3    sing N N 423 
PRO CG    CD     sing N N 424 
PRO CG    HG2    sing N N 425 
PRO CG    HG3    sing N N 426 
PRO CD    HD2    sing N N 427 
PRO CD    HD3    sing N N 428 
PRO OXT   HXT    sing N N 429 
SER N     CA     sing N N 430 
SER N     H      sing N N 431 
SER N     H2     sing N N 432 
SER CA    C      sing N N 433 
SER CA    CB     sing N N 434 
SER CA    HA     sing N N 435 
SER C     O      doub N N 436 
SER C     OXT    sing N N 437 
SER CB    OG     sing N N 438 
SER CB    HB2    sing N N 439 
SER CB    HB3    sing N N 440 
SER OG    HG     sing N N 441 
SER OXT   HXT    sing N N 442 
THR N     CA     sing N N 443 
THR N     H      sing N N 444 
THR N     H2     sing N N 445 
THR CA    C      sing N N 446 
THR CA    CB     sing N N 447 
THR CA    HA     sing N N 448 
THR C     O      doub N N 449 
THR C     OXT    sing N N 450 
THR CB    OG1    sing N N 451 
THR CB    CG2    sing N N 452 
THR CB    HB     sing N N 453 
THR OG1   HG1    sing N N 454 
THR CG2   HG21   sing N N 455 
THR CG2   HG22   sing N N 456 
THR CG2   HG23   sing N N 457 
THR OXT   HXT    sing N N 458 
TRP N     CA     sing N N 459 
TRP N     H      sing N N 460 
TRP N     H2     sing N N 461 
TRP CA    C      sing N N 462 
TRP CA    CB     sing N N 463 
TRP CA    HA     sing N N 464 
TRP C     O      doub N N 465 
TRP C     OXT    sing N N 466 
TRP CB    CG     sing N N 467 
TRP CB    HB2    sing N N 468 
TRP CB    HB3    sing N N 469 
TRP CG    CD1    doub Y N 470 
TRP CG    CD2    sing Y N 471 
TRP CD1   NE1    sing Y N 472 
TRP CD1   HD1    sing N N 473 
TRP CD2   CE2    doub Y N 474 
TRP CD2   CE3    sing Y N 475 
TRP NE1   CE2    sing Y N 476 
TRP NE1   HE1    sing N N 477 
TRP CE2   CZ2    sing Y N 478 
TRP CE3   CZ3    doub Y N 479 
TRP CE3   HE3    sing N N 480 
TRP CZ2   CH2    doub Y N 481 
TRP CZ2   HZ2    sing N N 482 
TRP CZ3   CH2    sing Y N 483 
TRP CZ3   HZ3    sing N N 484 
TRP CH2   HH2    sing N N 485 
TRP OXT   HXT    sing N N 486 
TYR N     CA     sing N N 487 
TYR N     H      sing N N 488 
TYR N     H2     sing N N 489 
TYR CA    C      sing N N 490 
TYR CA    CB     sing N N 491 
TYR CA    HA     sing N N 492 
TYR C     O      doub N N 493 
TYR C     OXT    sing N N 494 
TYR CB    CG     sing N N 495 
TYR CB    HB2    sing N N 496 
TYR CB    HB3    sing N N 497 
TYR CG    CD1    doub Y N 498 
TYR CG    CD2    sing Y N 499 
TYR CD1   CE1    sing Y N 500 
TYR CD1   HD1    sing N N 501 
TYR CD2   CE2    doub Y N 502 
TYR CD2   HD2    sing N N 503 
TYR CE1   CZ     doub Y N 504 
TYR CE1   HE1    sing N N 505 
TYR CE2   CZ     sing Y N 506 
TYR CE2   HE2    sing N N 507 
TYR CZ    OH     sing N N 508 
TYR OH    HH     sing N N 509 
TYR OXT   HXT    sing N N 510 
VAL N     CA     sing N N 511 
VAL N     H      sing N N 512 
VAL N     H2     sing N N 513 
VAL CA    C      sing N N 514 
VAL CA    CB     sing N N 515 
VAL CA    HA     sing N N 516 
VAL C     O      doub N N 517 
VAL C     OXT    sing N N 518 
VAL CB    CG1    sing N N 519 
VAL CB    CG2    sing N N 520 
VAL CB    HB     sing N N 521 
VAL CG1   HG11   sing N N 522 
VAL CG1   HG12   sing N N 523 
VAL CG1   HG13   sing N N 524 
VAL CG2   HG21   sing N N 525 
VAL CG2   HG22   sing N N 526 
VAL CG2   HG23   sing N N 527 
VAL OXT   HXT    sing N N 528 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8EDJ 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8TX4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.018085 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014711 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007818 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135  5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 24.64596 5.25405 ? ? 2.14387  29.76375 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N     . GLN A 1 11  ? 2.45428   -3.68338  59.73195 1.000 74.35972  ? 4   GLN A N     1 
ATOM   2    C  CA    . GLN A 1 11  ? 2.86894   -4.29942  58.47279 1.000 70.80414  ? 4   GLN A CA    1 
ATOM   3    C  C     . GLN A 1 11  ? 2.53619   -5.77109  58.36534 1.000 67.92910  ? 4   GLN A C     1 
ATOM   4    O  O     . GLN A 1 11  ? 2.52146   -6.49573  59.35858 1.000 71.79526  ? 4   GLN A O     1 
ATOM   5    C  CB    . GLN A 1 11  ? 4.36726   -4.09257  58.25169 1.000 76.16989  ? 4   GLN A CB    1 
ATOM   6    C  CG    . GLN A 1 11  ? 4.71246   -2.64223  58.32627 1.000 88.01901  ? 4   GLN A CG    1 
ATOM   7    C  CD    . GLN A 1 11  ? 4.66541   -2.01896  56.95033 1.000 94.51120  ? 4   GLN A CD    1 
ATOM   8    O  OE1   . GLN A 1 11  ? 3.70432   -1.33714  56.60799 1.000 91.56811  ? 4   GLN A OE1   1 
ATOM   9    N  NE2   . GLN A 1 11  ? 5.71397   -2.22130  56.16731 1.000 95.10910  ? 4   GLN A NE2   1 
ATOM   10   N  N     . ILE A 1 12  ? 2.26820   -6.18841  57.12446 1.000 55.89107  ? 5   ILE A N     1 
ATOM   11   C  CA    . ILE A 1 12  ? 1.88824   -7.56782  56.83734 1.000 62.28773  ? 5   ILE A CA    1 
ATOM   12   C  C     . ILE A 1 12  ? 2.91138   -8.54668  57.38704 1.000 60.88462  ? 5   ILE A C     1 
ATOM   13   O  O     . ILE A 1 12  ? 2.56091   -9.66234  57.79010 1.000 57.61415  ? 5   ILE A O     1 
ATOM   14   C  CB    . ILE A 1 12  ? 1.68662   -7.74386  55.31906 1.000 53.86061  ? 5   ILE A CB    1 
ATOM   15   C  CG1   . ILE A 1 12  ? 0.72521   -6.67514  54.80108 1.000 51.50484  ? 5   ILE A CG1   1 
ATOM   16   C  CG2   . ILE A 1 12  ? 1.18451   -9.14266  54.99462 1.000 48.85962  ? 5   ILE A CG2   1 
ATOM   17   C  CD1   . ILE A 1 12  ? -0.02532  -7.07871  53.56649 1.000 49.07462  ? 5   ILE A CD1   1 
ATOM   18   N  N     . ARG A 1 13  ? 4.18508   -8.14771  57.42765 1.000 75.47630  ? 6   ARG A N     1 
ATOM   19   C  CA    . ARG A 1 13  ? 5.20763   -9.00805  58.01284 1.000 80.11749  ? 6   ARG A CA    1 
ATOM   20   C  C     . ARG A 1 13  ? 4.97977   -9.21910  59.50442 1.000 72.58104  ? 6   ARG A C     1 
ATOM   21   O  O     . ARG A 1 13  ? 5.30677   -10.28549 60.03765 1.000 79.61359  ? 6   ARG A O     1 
ATOM   22   C  CB    . ARG A 1 13  ? 6.59504   -8.42049  57.75141 1.000 82.87041  ? 6   ARG A CB    1 
ATOM   23   C  CG    . ARG A 1 13  ? 7.11044   -8.68456  56.34115 1.000 88.00895  ? 6   ARG A CG    1 
ATOM   24   C  CD    . ARG A 1 13  ? 6.57114   -10.00938 55.79298 1.000 79.57545  ? 6   ARG A CD    1 
ATOM   25   N  NE    . ARG A 1 13  ? 6.83969   -10.18030 54.36963 1.000 77.28777  ? 6   ARG A NE    1 
ATOM   26   C  CZ    . ARG A 1 13  ? 8.02331   -10.49108 53.85720 1.000 72.40717  ? 6   ARG A CZ    1 
ATOM   27   N  NH1   . ARG A 1 13  ? 9.08346   -10.68312 54.62636 1.000 73.15375  ? 6   ARG A NH1   1 
ATOM   28   N  NH2   . ARG A 1 13  ? 8.14711   -10.60990 52.53888 1.000 71.66454  ? 6   ARG A NH2   1 
ATOM   29   N  N     . ASN A 1 14  ? 4.41236   -8.23011  60.19026 1.000 66.10267  ? 7   ASN A N     1 
ATOM   30   C  CA    . ASN A 1 14  ? 4.06858   -8.39287  61.59664 1.000 61.34337  ? 7   ASN A CA    1 
ATOM   31   C  C     . ASN A 1 14  ? 2.71340   -9.06201  61.80524 1.000 62.80939  ? 7   ASN A C     1 
ATOM   32   O  O     . ASN A 1 14  ? 2.40268   -9.45517  62.93621 1.000 50.59886  ? 7   ASN A O     1 
ATOM   33   C  CB    . ASN A 1 14  ? 4.08287   -7.03455  62.30374 1.000 68.07703  ? 7   ASN A CB    1 
ATOM   34   C  CG    . ASN A 1 14  ? 5.36386   -6.79691  63.09766 1.000 83.60770  ? 7   ASN A CG    1 
ATOM   35   O  OD1   . ASN A 1 14  ? 6.00876   -5.75281  62.96301 1.000 85.34157  ? 7   ASN A OD1   1 
ATOM   36   N  ND2   . ASN A 1 14  ? 5.73838   -7.76992  63.92785 1.000 76.15356  ? 7   ASN A ND2   1 
ATOM   37   N  N     . MET A 1 15  ? 1.89856   -9.20214  60.75545 1.000 53.77310  ? 8   MET A N     1 
ATOM   38   C  CA    . MET A 1 15  ? 0.58277   -9.81384  60.89653 1.000 44.51299  ? 8   MET A CA    1 
ATOM   39   C  C     . MET A 1 15  ? 0.56045   -11.28371 60.52092 1.000 45.96419  ? 8   MET A C     1 
ATOM   40   O  O     . MET A 1 15  ? -0.40086  -11.98658 60.86350 1.000 41.55969  ? 8   MET A O     1 
ATOM   41   C  CB    . MET A 1 15  ? -0.45133  -9.07691  60.03609 1.000 45.21011  ? 8   MET A CB    1 
ATOM   42   C  CG    . MET A 1 15  ? -0.37173  -7.57123  60.14800 1.000 43.64450  ? 8   MET A CG    1 
ATOM   43   S  SD    . MET A 1 15  ? -1.41750  -6.72276  58.95938 1.000 41.29351  ? 8   MET A SD    1 
ATOM   44   C  CE    . MET A 1 15  ? -1.82130  -5.21941  59.86317 1.000 39.48648  ? 8   MET A CE    1 
ATOM   45   N  N     . VAL A 1 16  ? 1.58216   -11.77208 59.82615 1.000 43.09493  ? 9   VAL A N     1 
ATOM   46   C  CA    . VAL A 1 16  ? 1.55165   -13.13361 59.32401 1.000 39.29136  ? 9   VAL A CA    1 
ATOM   47   C  C     . VAL A 1 16  ? 2.93457   -13.76082 59.45638 1.000 38.38464  ? 9   VAL A C     1 
ATOM   48   O  O     . VAL A 1 16  ? 3.95228   -13.07417 59.55447 1.000 45.62018  ? 9   VAL A O     1 
ATOM   49   C  CB    . VAL A 1 16  ? 1.04463   -13.16776 57.86007 1.000 40.20101  ? 9   VAL A CB    1 
ATOM   50   C  CG1   . VAL A 1 16  ? 2.17409   -12.87984 56.86800 1.000 36.31160  ? 9   VAL A CG1   1 
ATOM   51   C  CG2   . VAL A 1 16  ? 0.35456   -14.45861 57.58271 1.000 39.69284  ? 9   VAL A CG2   1 
ATOM   52   N  N     . GLU A 1 17  ? 2.94893   -15.08575 59.49541 1.000 44.47813  ? 10  GLU A N     1 
ATOM   53   C  CA    . GLU A 1 17  ? 4.14261   -15.91170 59.35167 1.000 51.55779  ? 10  GLU A CA    1 
ATOM   54   C  C     . GLU A 1 17  ? 4.47350   -16.09926 57.87621 1.000 33.29922  ? 10  GLU A C     1 
ATOM   55   O  O     . GLU A 1 17  ? 3.87126   -16.96730 57.23725 1.000 38.15711  ? 10  GLU A O     1 
ATOM   56   C  CB    . GLU A 1 17  ? 3.91500   -17.28362 59.99100 1.000 47.86161  ? 10  GLU A CB    1 
ATOM   57   C  CG    . GLU A 1 17  ? 5.17402   -18.04306 60.36982 1.000 64.22761  ? 10  GLU A CG    1 
ATOM   58   C  CD    . GLU A 1 17  ? 6.01134   -17.31658 61.40190 1.000 58.26709  ? 10  GLU A CD    1 
ATOM   59   O  OE1   . GLU A 1 17  ? 7.19023   -17.02485 61.11165 1.000 58.30621  ? 10  GLU A OE1   1 
ATOM   60   O  OE2   . GLU A 1 17  ? 5.48339   -17.03348 62.49768 1.000 65.03336  ? 10  GLU A OE2   1 
ATOM   61   N  N     . PRO A 1 18  ? 5.41913   -15.34427 57.30635 1.000 38.02993  ? 11  PRO A N     1 
ATOM   62   C  CA    . PRO A 1 18  ? 5.68292   -15.46516 55.86262 1.000 32.06885  ? 11  PRO A CA    1 
ATOM   63   C  C     . PRO A 1 18  ? 6.12032   -16.87636 55.49334 1.000 37.06836  ? 11  PRO A C     1 
ATOM   64   O  O     . PRO A 1 18  ? 6.88979   -17.51847 56.21141 1.000 34.96801  ? 11  PRO A O     1 
ATOM   65   C  CB    . PRO A 1 18  ? 6.79935   -14.44353 55.60767 1.000 42.73544  ? 11  PRO A CB    1 
ATOM   66   C  CG    . PRO A 1 18  ? 7.34020   -14.09086 56.96257 1.000 45.33433  ? 11  PRO A CG    1 
ATOM   67   C  CD    . PRO A 1 18  ? 6.22581   -14.28673 57.93037 1.000 47.11858  ? 11  PRO A CD    1 
ATOM   68   N  N     . MET A 1 19  ? 5.60082   -17.36989 54.37347 1.000 26.05887  ? 12  MET A N     1 
ATOM   69   C  CA    . MET A 1 19  ? 5.91485   -18.73687 53.99313 1.000 30.01455  ? 12  MET A CA    1 
ATOM   70   C  C     . MET A 1 19  ? 7.31303   -18.85002 53.38773 1.000 24.75230  ? 12  MET A C     1 
ATOM   71   O  O     . MET A 1 19  ? 7.91860   -17.87157 52.95147 1.000 27.61759  ? 12  MET A O     1 
ATOM   72   C  CB    . MET A 1 19  ? 4.88285   -19.32248 53.01682 1.000 33.15806  ? 12  MET A CB    1 
ATOM   73   C  CG    . MET A 1 19  ? 5.04594   -18.90526 51.54742 1.000 30.50482  ? 12  MET A CG    1 
ATOM   74   S  SD    . MET A 1 19  ? 3.67074   -19.42747 50.47311 1.000 29.06876  ? 12  MET A SD    1 
ATOM   75   C  CE    . MET A 1 19  ? 2.23939   -18.56723 51.06963 1.000 22.77330  ? 12  MET A CE    1 
ATOM   76   N  N     . ASP A 1 20  ? 7.81072   -20.08033 53.37299 1.000 26.80856  ? 13  ASP A N     1 
ATOM   77   C  CA    . ASP A 1 20  ? 9.10012   -20.38217 52.77435 1.000 25.01940  ? 13  ASP A CA    1 
ATOM   78   C  C     . ASP A 1 20  ? 9.06067   -20.09203 51.27600 1.000 25.82410  ? 13  ASP A C     1 
ATOM   79   O  O     . ASP A 1 20  ? 8.04507   -20.35805 50.62145 1.000 25.53370  ? 13  ASP A O     1 
ATOM   80   C  CB    . ASP A 1 20  ? 9.44291   -21.85637 53.03338 1.000 30.25067  ? 13  ASP A CB    1 
ATOM   81   C  CG    . ASP A 1 20  ? 10.85575  -22.22350 52.62256 1.000 30.27295  ? 13  ASP A CG    1 
ATOM   82   O  OD1   . ASP A 1 20  ? 11.69186  -22.50946 53.50654 1.000 34.45274  ? 13  ASP A OD1   1 
ATOM   83   O  OD2   . ASP A 1 20  ? 11.12574  -22.28537 51.40779 1.000 32.90768  ? 13  ASP A OD2   1 
ATOM   84   N  N     . PRO A 1 21  ? 10.13679  -19.53396 50.70428 1.000 25.79886  ? 14  PRO A N     1 
ATOM   85   C  CA    . PRO A 1 21  ? 10.13641  -19.26320 49.25495 1.000 27.29038  ? 14  PRO A CA    1 
ATOM   86   C  C     . PRO A 1 21  ? 9.89068   -20.50512 48.41029 1.000 27.78801  ? 14  PRO A C     1 
ATOM   87   O  O     . PRO A 1 21  ? 9.25334   -20.41200 47.35632 1.000 26.23677  ? 14  PRO A O     1 
ATOM   88   C  CB    . PRO A 1 21  ? 11.53772  -18.68781 49.00384 1.000 31.80704  ? 14  PRO A CB    1 
ATOM   89   C  CG    . PRO A 1 21  ? 12.01123  -18.20419 50.33572 1.000 30.43640  ? 14  PRO A CG    1 
ATOM   90   C  CD    . PRO A 1 21  ? 11.39496  -19.11671 51.35275 1.000 32.02755  ? 14  PRO A CD    1 
ATOM   91   N  N     . ARG A 1 22  ? 10.40486  -21.66362 48.82846 1.000 24.12473  ? 15  ARG A N     1 
ATOM   92   C  CA    . ARG A 1 22  ? 10.14054  -22.88930 48.07496 1.000 24.24163  ? 15  ARG A CA    1 
ATOM   93   C  C     . ARG A 1 22  ? 8.67141   -23.27773 48.17347 1.000 25.54137  ? 15  ARG A C     1 
ATOM   94   O  O     . ARG A 1 22  ? 8.08440   -23.77439 47.20594 1.000 24.81409  ? 15  ARG A O     1 
ATOM   95   C  CB    . ARG A 1 22  ? 11.03706  -24.02143 48.58353 1.000 25.61447  ? 15  ARG A CB    1 
ATOM   96   C  CG    . ARG A 1 22  ? 10.70541  -25.41588 47.99659 1.000 41.43750  ? 15  ARG A CG    1 
ATOM   97   C  CD    . ARG A 1 22  ? 11.45837  -25.71993 46.68599 1.000 53.08799  ? 15  ARG A CD    1 
ATOM   98   N  NE    . ARG A 1 22  ? 11.46278  -27.13874 46.31441 1.000 60.22554  ? 15  ARG A NE    1 
ATOM   99   C  CZ    . ARG A 1 22  ? 11.97878  -28.12895 47.04112 1.000 59.57116  ? 15  ARG A CZ    1 
ATOM   100  N  NH1   . ARG A 1 22  ? 12.57115  -27.90459 48.20415 1.000 52.53064  ? 15  ARG A NH1   1 
ATOM   101  N  NH2   . ARG A 1 22  ? 11.91289  -29.37936 46.58029 1.000 50.07464  ? 15  ARG A NH2   1 
ATOM   102  N  N     . THR A 1 23  ? 8.05759   -23.05287 49.33753 1.000 25.80668  ? 16  THR A N     1 
ATOM   103  C  CA    . THR A 1 23  ? 6.62592   -23.29408 49.47284 1.000 22.79154  ? 16  THR A CA    1 
ATOM   104  C  C     . THR A 1 23  ? 5.83839   -22.41711 48.50829 1.000 21.50728  ? 16  THR A C     1 
ATOM   105  O  O     . THR A 1 23  ? 4.88483   -22.87686 47.86003 1.000 19.31682  ? 16  THR A O     1 
ATOM   106  C  CB    . THR A 1 23  ? 6.18361   -23.03900 50.91363 1.000 23.61208  ? 16  THR A CB    1 
ATOM   107  O  OG1   . THR A 1 23  ? 6.96968   -23.83586 51.79451 1.000 21.38492  ? 16  THR A OG1   1 
ATOM   108  C  CG2   . THR A 1 23  ? 4.72234   -23.42562 51.09717 1.000 21.69159  ? 16  THR A CG2   1 
ATOM   109  N  N     . PHE A 1 24  ? 6.24238   -21.15264 48.36596 1.000 18.50123  ? 17  PHE A N     1 
ATOM   110  C  CA    . PHE A 1 24  ? 5.51980   -20.26101 47.46662 1.000 19.64262  ? 17  PHE A CA    1 
ATOM   111  C  C     . PHE A 1 24  ? 5.69504   -20.67819 46.01108 1.000 18.02662  ? 17  PHE A C     1 
ATOM   112  O  O     . PHE A 1 24  ? 4.71339   -20.86218 45.28509 1.000 21.29461  ? 17  PHE A O     1 
ATOM   113  C  CB    . PHE A 1 24  ? 5.97794   -18.81689 47.67238 1.000 18.56749  ? 17  PHE A CB    1 
ATOM   114  C  CG    . PHE A 1 24  ? 5.39737   -17.86976 46.67267 1.000 19.91685  ? 17  PHE A CG    1 
ATOM   115  C  CD1   . PHE A 1 24  ? 4.09441   -17.40656 46.81162 1.000 21.17398  ? 17  PHE A CD1   1 
ATOM   116  C  CD2   . PHE A 1 24  ? 6.13975   -17.45559 45.59068 1.000 24.84640  ? 17  PHE A CD2   1 
ATOM   117  C  CE1   . PHE A 1 24  ? 3.54967   -16.51964 45.88356 1.000 23.04029  ? 17  PHE A CE1   1 
ATOM   118  C  CE2   . PHE A 1 24  ? 5.59793   -16.56759 44.64853 1.000 25.22112  ? 17  PHE A CE2   1 
ATOM   119  C  CZ    . PHE A 1 24  ? 4.30082   -16.10792 44.80914 1.000 22.86539  ? 17  PHE A CZ    1 
ATOM   120  N  N     . VAL A 1 25  ? 6.93983   -20.85431 45.56802 1.000 20.59169  ? 18  VAL A N     1 
ATOM   121  C  CA    . VAL A 1 25  ? 7.18719   -21.10860 44.15009 1.000 21.35988  ? 18  VAL A CA    1 
ATOM   122  C  C     . VAL A 1 25  ? 6.55907   -22.43226 43.71137 1.000 24.09738  ? 18  VAL A C     1 
ATOM   123  O  O     . VAL A 1 25  ? 6.02428   -22.53972 42.60281 1.000 21.92295  ? 18  VAL A O     1 
ATOM   124  C  CB    . VAL A 1 25  ? 8.70065   -21.07245 43.86402 1.000 24.53107  ? 18  VAL A CB    1 
ATOM   125  C  CG1   . VAL A 1 25  ? 8.98207   -21.58949 42.48060 1.000 37.83332  ? 18  VAL A CG1   1 
ATOM   126  C  CG2   . VAL A 1 25  ? 9.22400   -19.62940 43.99304 1.000 25.15378  ? 18  VAL A CG2   1 
ATOM   127  N  N     . SER A 1 26  ? 6.59440   -23.44873 44.56856 1.000 19.28882  ? 19  SER A N     1 
ATOM   128  C  CA    . SER A 1 26  ? 6.06024   -24.74720 44.16541 1.000 20.53628  ? 19  SER A CA    1 
ATOM   129  C  C     . SER A 1 26  ? 4.54076   -24.73008 44.12935 1.000 24.02897  ? 19  SER A C     1 
ATOM   130  O  O     . SER A 1 26  ? 3.93279   -25.38556 43.27916 1.000 22.25419  ? 19  SER A O     1 
ATOM   131  C  CB    . SER A 1 26  ? 6.56495   -25.84906 45.09978 1.000 22.70800  ? 19  SER A CB    1 
ATOM   132  O  OG    . SER A 1 26  ? 6.10276   -25.66909 46.43138 1.000 23.69992  ? 19  SER A OG    1 
ATOM   133  N  N     . ASN A 1 27  ? 3.91191   -23.96681 45.01511 1.000 19.31285  ? 20  ASN A N     1 
ATOM   134  C  CA    . ASN A 1 27  ? 2.46040   -23.95499 45.12292 1.000 17.63598  ? 20  ASN A CA    1 
ATOM   135  C  C     . ASN A 1 27  ? 1.79401   -22.92705 44.22473 1.000 18.22537  ? 20  ASN A C     1 
ATOM   136  O  O     . ASN A 1 27  ? 0.61488   -23.09454 43.88478 1.000 17.42879  ? 20  ASN A O     1 
ATOM   137  C  CB    . ASN A 1 27  ? 2.04281   -23.67845 46.56967 1.000 18.59413  ? 20  ASN A CB    1 
ATOM   138  C  CG    . ASN A 1 27  ? 2.08713   -24.91714 47.42725 1.000 20.09731  ? 20  ASN A CG    1 
ATOM   139  O  OD1   . ASN A 1 27  ? 2.95175   -25.05398 48.29636 1.000 23.06591  ? 20  ASN A OD1   1 
ATOM   140  N  ND2   . ASN A 1 27  ? 1.16634   -25.83397 47.18740 1.000 16.85932  ? 20  ASN A ND2   1 
ATOM   141  N  N     . PHE A 1 28  ? 2.48953   -21.85225 43.85810 1.000 16.38061  ? 21  PHE A N     1 
ATOM   142  C  CA    . PHE A 1 28  ? 1.87414   -20.80424 43.05843 1.000 17.41967  ? 21  PHE A CA    1 
ATOM   143  C  C     . PHE A 1 28  ? 2.32352   -20.79853 41.59619 1.000 17.84652  ? 21  PHE A C     1 
ATOM   144  O  O     . PHE A 1 28  ? 1.82115   -19.98434 40.81204 1.000 17.36067  ? 21  PHE A O     1 
ATOM   145  C  CB    . PHE A 1 28  ? 2.12806   -19.44327 43.71722 1.000 16.87478  ? 21  PHE A CB    1 
ATOM   146  C  CG    . PHE A 1 28  ? 1.20233   -19.17333 44.87238 1.000 18.61793  ? 21  PHE A CG    1 
ATOM   147  C  CD1   . PHE A 1 28  ? 1.48795   -19.67193 46.14014 1.000 19.93736  ? 21  PHE A CD1   1 
ATOM   148  C  CD2   . PHE A 1 28  ? 0.02548   -18.47915 44.68193 1.000 19.44743  ? 21  PHE A CD2   1 
ATOM   149  C  CE1   . PHE A 1 28  ? 0.62554   -19.43881 47.21192 1.000 22.81061  ? 21  PHE A CE1   1 
ATOM   150  C  CE2   . PHE A 1 28  ? -0.84438  -18.23805 45.73987 1.000 19.86240  ? 21  PHE A CE2   1 
ATOM   151  C  CZ    . PHE A 1 28  ? -0.54120  -18.71773 47.01398 1.000 21.20298  ? 21  PHE A CZ    1 
ATOM   152  N  N     . ASN A 1 29  ? 3.23916   -21.68139 41.20525 1.000 21.36629  ? 22  ASN A N     1 
ATOM   153  C  CA    . ASN A 1 29  ? 3.53887   -21.85736 39.78843 1.000 23.07033  ? 22  ASN A CA    1 
ATOM   154  C  C     . ASN A 1 29  ? 2.24637   -21.98849 38.98857 1.000 21.99441  ? 22  ASN A C     1 
ATOM   155  O  O     . ASN A 1 29  ? 1.36267   -22.76758 39.35311 1.000 21.18400  ? 22  ASN A O     1 
ATOM   156  C  CB    . ASN A 1 29  ? 4.40381   -23.09506 39.58996 1.000 22.32330  ? 22  ASN A CB    1 
ATOM   157  C  CG    . ASN A 1 29  ? 4.81860   -23.25986 38.14807 1.000 35.30562  ? 22  ASN A CG    1 
ATOM   158  O  OD1   . ASN A 1 29  ? 4.05399   -23.77044 37.33331 1.000 27.17163  ? 22  ASN A OD1   1 
ATOM   159  N  ND2   . ASN A 1 29  ? 6.02187   -22.79843 37.81855 1.000 35.20799  ? 22  ASN A ND2   1 
ATOM   160  N  N     . ASN A 1 30  ? 2.12308   -21.21974 37.89743 1.000 18.77876  ? 23  ASN A N     1 
ATOM   161  C  CA    . ASN A 1 30  ? 0.83252   -21.12523 37.22543 1.000 16.98426  ? 23  ASN A CA    1 
ATOM   162  C  C     . ASN A 1 30  ? 0.74115   -21.98414 35.96483 1.000 18.45264  ? 23  ASN A C     1 
ATOM   163  O  O     . ASN A 1 30  ? -0.10560  -21.71998 35.10616 1.000 19.41080  ? 23  ASN A O     1 
ATOM   164  C  CB    . ASN A 1 30  ? 0.45866   -19.65714 36.93638 1.000 17.11131  ? 23  ASN A CB    1 
ATOM   165  C  CG    . ASN A 1 30  ? 1.35252   -18.97788 35.89987 1.000 18.47769  ? 23  ASN A CG    1 
ATOM   166  O  OD1   . ASN A 1 30  ? 2.44089   -19.44061 35.59945 1.000 20.67531  ? 23  ASN A OD1   1 
ATOM   167  N  ND2   . ASN A 1 30  ? 0.89832   -17.83919 35.38646 1.000 18.57429  ? 23  ASN A ND2   1 
ATOM   168  N  N     . ARG A 1 31  ? 1.52320   -23.05048 35.87105 1.000 22.09725  ? 24  ARG A N     1 
ATOM   169  C  CA    . ARG A 1 31  ? 1.27653   -24.00522 34.79372 1.000 21.97161  ? 24  ARG A CA    1 
ATOM   170  C  C     . ARG A 1 31  ? -0.16036  -24.50661 34.93177 1.000 20.57823  ? 24  ARG A C     1 
ATOM   171  O  O     . ARG A 1 31  ? -0.54183  -24.96487 36.02189 1.000 21.05167  ? 24  ARG A O     1 
ATOM   172  C  CB    . ARG A 1 31  ? 2.25786   -25.17069 34.83970 1.000 23.24040  ? 24  ARG A CB    1 
ATOM   173  C  CG    . ARG A 1 31  ? 2.04209   -26.16913 33.70761 1.000 23.35222  ? 24  ARG A CG    1 
ATOM   174  C  CD    . ARG A 1 31  ? 3.07883   -27.28890 33.73604 1.000 31.92829  ? 24  ARG A CD    1 
ATOM   175  N  NE    . ARG A 1 31  ? 3.36238   -27.76582 32.38513 1.000 41.92009  ? 24  ARG A NE    1 
ATOM   176  C  CZ    . ARG A 1 31  ? 2.63343   -28.66778 31.73950 1.000 38.43789  ? 24  ARG A CZ    1 
ATOM   177  N  NH1   . ARG A 1 31  ? 1.56600   -29.22234 32.29506 1.000 28.46714  ? 24  ARG A NH1   1 
ATOM   178  N  NH2   . ARG A 1 31  ? 2.98464   -29.02358 30.50490 1.000 41.51123  ? 24  ARG A NH2   1 
ATOM   179  N  N     . PRO A 1 32  ? -1.00027  -24.38413 33.89769 1.000 20.85904  ? 25  PRO A N     1 
ATOM   180  C  CA    . PRO A 1 32  ? -2.42936  -24.69806 34.08714 1.000 21.07553  ? 25  PRO A CA    1 
ATOM   181  C  C     . PRO A 1 32  ? -2.69581  -26.12918 34.51570 1.000 24.10448  ? 25  PRO A C     1 
ATOM   182  O  O     . PRO A 1 32  ? -3.59133  -26.36715 35.33428 1.000 22.45950  ? 25  PRO A O     1 
ATOM   183  C  CB    . PRO A 1 32  ? -3.02865  -24.39178 32.70833 1.000 24.46635  ? 25  PRO A CB    1 
ATOM   184  C  CG    . PRO A 1 32  ? -2.17638  -23.25353 32.20961 1.000 25.94737  ? 25  PRO A CG    1 
ATOM   185  C  CD    . PRO A 1 32  ? -0.77103  -23.61281 32.65266 1.000 26.47807  ? 25  PRO A CD    1 
ATOM   186  N  N     . ILE A 1 33  ? -1.96045  -27.08771 33.97353 1.000 22.41905  ? 26  ILE A N     1 
ATOM   187  C  CA    . ILE A 1 33  ? -2.08506  -28.49254 34.35338 1.000 22.35239  ? 26  ILE A CA    1 
ATOM   188  C  C     . ILE A 1 33  ? -0.87979  -28.81375 35.21945 1.000 26.79728  ? 26  ILE A C     1 
ATOM   189  O  O     . ILE A 1 33  ? 0.26059   -28.82387 34.73929 1.000 24.89285  ? 26  ILE A O     1 
ATOM   190  C  CB    . ILE A 1 33  ? -2.17746  -29.41487 33.13050 1.000 21.45559  ? 26  ILE A CB    1 
ATOM   191  C  CG1   . ILE A 1 33  ? -3.30768  -28.95036 32.21121 1.000 24.74693  ? 26  ILE A CG1   1 
ATOM   192  C  CG2   . ILE A 1 33  ? -2.39759  -30.87766 33.54974 1.000 21.65983  ? 26  ILE A CG2   1 
ATOM   193  C  CD1   . ILE A 1 33  ? -4.67554  -28.93705 32.89462 1.000 23.20882  ? 26  ILE A CD1   1 
ATOM   194  N  N     . LEU A 1 34  ? -1.12311  -29.05726 36.50533 1.000 22.45612  ? 27  LEU A N     1 
ATOM   195  C  CA    . LEU A 1 34  ? -0.02115  -29.19462 37.45220 1.000 22.39336  ? 27  LEU A CA    1 
ATOM   196  C  C     . LEU A 1 34  ? -0.42051  -30.25062 38.47160 1.000 24.53452  ? 27  LEU A C     1 
ATOM   197  O  O     . LEU A 1 34  ? -1.32496  -30.02403 39.28108 1.000 21.91913  ? 27  LEU A O     1 
ATOM   198  C  CB    . LEU A 1 34  ? 0.29552   -27.84211 38.11068 1.000 21.10465  ? 27  LEU A CB    1 
ATOM   199  C  CG    . LEU A 1 34  ? 1.50086   -27.68949 39.05365 1.000 33.64071  ? 27  LEU A CG    1 
ATOM   200  C  CD1   . LEU A 1 34  ? 2.73956   -28.43823 38.59004 1.000 37.47389  ? 27  LEU A CD1   1 
ATOM   201  C  CD2   . LEU A 1 34  ? 1.83130   -26.20985 39.25022 1.000 23.84402  ? 27  LEU A CD2   1 
ATOM   202  N  N     . SER A 1 35  ? 0.23063   -31.40355 38.40704 1.000 23.80878  ? 28  SER A N     1 
ATOM   203  C  CA    . SER A 1 35  ? -0.07808  -32.53712 39.26159 1.000 24.91102  ? 28  SER A CA    1 
ATOM   204  C  C     . SER A 1 35  ? 0.83538   -32.56235 40.48308 1.000 25.11091  ? 28  SER A C     1 
ATOM   205  O  O     . SER A 1 35  ? 1.87853   -31.90127 40.53306 1.000 24.31799  ? 28  SER A O     1 
ATOM   206  C  CB    . SER A 1 35  ? 0.03820   -33.85240 38.48003 1.000 31.47550  ? 28  SER A CB    1 
ATOM   207  O  OG    . SER A 1 35  ? -0.76525  -33.81518 37.31207 1.000 28.57467  ? 28  SER A OG    1 
ATOM   208  N  N     . GLY A 1 36  ? 0.41275   -33.33115 41.48277 1.000 19.40277  ? 29  GLY A N     1 
ATOM   209  C  CA    . GLY A 1 36  ? 1.20648   -33.56981 42.66756 1.000 22.41456  ? 29  GLY A CA    1 
ATOM   210  C  C     . GLY A 1 36  ? 0.99710   -32.60147 43.81831 1.000 24.64676  ? 29  GLY A C     1 
ATOM   211  O  O     . GLY A 1 36  ? 1.60707   -32.79468 44.87694 1.000 25.00272  ? 29  GLY A O     1 
ATOM   212  N  N     . LEU A 1 37  ? 0.16339   -31.57478 43.66408 1.000 21.13107  ? 30  LEU A N     1 
ATOM   213  C  CA    . LEU A 1 37  ? -0.03027  -30.58802 44.72876 1.000 22.10323  ? 30  LEU A CA    1 
ATOM   214  C  C     . LEU A 1 37  ? -1.13378  -31.07590 45.67100 1.000 27.32421  ? 30  LEU A C     1 
ATOM   215  O  O     . LEU A 1 37  ? -2.29212  -31.21022 45.26990 1.000 38.10902  ? 30  LEU A O     1 
ATOM   216  C  CB    . LEU A 1 37  ? -0.35486  -29.21503 44.13828 1.000 23.17627  ? 30  LEU A CB    1 
ATOM   217  C  CG    . LEU A 1 37  ? 0.80254   -28.55660 43.36805 1.000 21.78310  ? 30  LEU A CG    1 
ATOM   218  C  CD1   . LEU A 1 37  ? 0.40339   -27.22080 42.77826 1.000 23.37590  ? 30  LEU A CD1   1 
ATOM   219  C  CD2   . LEU A 1 37  ? 2.02297   -28.37855 44.26901 1.000 24.54407  ? 30  LEU A CD2   1 
ATOM   220  N  N     . ASP A 1 38  ? -0.78292  -31.33287 46.92613 1.000 29.22061  ? 31  ASP A N     1 
ATOM   221  C  CA    . ASP A 1 38  ? -1.76257  -31.84405 47.87619 1.000 35.92133  ? 31  ASP A CA    1 
ATOM   222  C  C     . ASP A 1 38  ? -2.43745  -30.75248 48.70360 1.000 35.21479  ? 31  ASP A C     1 
ATOM   223  O  O     . ASP A 1 38  ? -3.26562  -31.07651 49.55858 1.000 34.01113  ? 31  ASP A O     1 
ATOM   224  C  CB    . ASP A 1 38  ? -1.11115  -32.90025 48.79553 1.000 31.17594  ? 31  ASP A CB    1 
ATOM   225  C  CG    . ASP A 1 38  ? 0.01188   -32.34176 49.68374 1.000 41.66720  ? 31  ASP A CG    1 
ATOM   226  O  OD1   . ASP A 1 38  ? 0.44895   -31.18030 49.50818 1.000 40.97587  ? 31  ASP A OD1   1 
ATOM   227  O  OD2   . ASP A 1 38  ? 0.48655   -33.10401 50.55788 1.000 38.12848  ? 31  ASP A OD2   1 
ATOM   228  N  N     . THR A 1 39  ? -2.15077  -29.47510 48.44729 1.000 25.62036  ? 32  THR A N     1 
ATOM   229  C  CA    . THR A 1 39  ? -2.56599  -28.41179 49.35860 1.000 25.83073  ? 32  THR A CA    1 
ATOM   230  C  C     . THR A 1 39  ? -3.02800  -27.19271 48.56193 1.000 25.83190  ? 32  THR A C     1 
ATOM   231  O  O     . THR A 1 39  ? -2.53972  -26.94152 47.45609 1.000 21.74661  ? 32  THR A O     1 
ATOM   232  C  CB    . THR A 1 39  ? -1.39838  -28.04873 50.29416 1.000 26.64073  ? 32  THR A CB    1 
ATOM   233  O  OG1   . THR A 1 39  ? -0.92583  -29.24037 50.94122 1.000 37.67647  ? 32  THR A OG1   1 
ATOM   234  C  CG2   . THR A 1 39  ? -1.82442  -27.03627 51.37384 1.000 22.99493  ? 32  THR A CG2   1 
ATOM   235  N  N     . VAL A 1 40  ? -4.01144  -26.46076 49.11400 1.000 24.61068  ? 33  VAL A N     1 
ATOM   236  C  CA    . VAL A 1 40  ? -4.41898  -25.14717 48.60978 1.000 20.65761  ? 33  VAL A CA    1 
ATOM   237  C  C     . VAL A 1 40  ? -3.88698  -24.10390 49.57788 1.000 21.31248  ? 33  VAL A C     1 
ATOM   238  O  O     . VAL A 1 40  ? -4.00800  -24.26527 50.80218 1.000 24.20135  ? 33  VAL A O     1 
ATOM   239  C  CB    . VAL A 1 40  ? -5.95415  -25.02268 48.48162 1.000 24.08595  ? 33  VAL A CB    1 
ATOM   240  C  CG1   . VAL A 1 40  ? -6.34847  -23.69487 47.80665 1.000 24.11290  ? 33  VAL A CG1   1 
ATOM   241  C  CG2   . VAL A 1 40  ? -6.54301  -26.19342 47.73548 1.000 22.96132  ? 33  VAL A CG2   1 
ATOM   242  N  N     . TRP A 1 41  ? -3.29280  -23.03368 49.04085 1.000 20.98013  ? 34  TRP A N     1 
ATOM   243  C  CA    . TRP A 1 41  ? -2.79479  -21.91712 49.83742 1.000 19.66844  ? 34  TRP A CA    1 
ATOM   244  C  C     . TRP A 1 41  ? -3.59239  -20.66322 49.52453 1.000 23.22893  ? 34  TRP A C     1 
ATOM   245  O  O     . TRP A 1 41  ? -3.98725  -20.43729 48.37881 1.000 19.05541  ? 34  TRP A O     1 
ATOM   246  C  CB    . TRP A 1 41  ? -1.30692  -21.66192 49.57613 1.000 19.86883  ? 34  TRP A CB    1 
ATOM   247  C  CG    . TRP A 1 41  ? -0.47117  -22.72218 50.20256 1.000 22.51305  ? 34  TRP A CG    1 
ATOM   248  C  CD1   . TRP A 1 41  ? -0.20645  -23.96953 49.69925 1.000 21.13930  ? 34  TRP A CD1   1 
ATOM   249  C  CD2   . TRP A 1 41  ? 0.17310   -22.65059 51.47198 1.000 21.66324  ? 34  TRP A CD2   1 
ATOM   250  N  NE1   . TRP A 1 41  ? 0.57899   -24.68137 50.59075 1.000 21.98156  ? 34  TRP A NE1   1 
ATOM   251  C  CE2   . TRP A 1 41  ? 0.82363   -23.88726 51.68426 1.000 30.93631  ? 34  TRP A CE2   1 
ATOM   252  C  CE3   . TRP A 1 41  ? 0.26620   -21.65995 52.45700 1.000 22.44848  ? 34  TRP A CE3   1 
ATOM   253  C  CZ2   . TRP A 1 41  ? 1.56369   -24.14814 52.83599 1.000 30.77334  ? 34  TRP A CZ2   1 
ATOM   254  C  CZ3   . TRP A 1 41  ? 0.99956   -21.92368 53.59594 1.000 29.05523  ? 34  TRP A CZ3   1 
ATOM   255  C  CH2   . TRP A 1 41  ? 1.63599   -23.16092 53.77699 1.000 31.48709  ? 34  TRP A CH2   1 
ATOM   256  N  N     . LEU A 1 42  ? -3.82972  -19.85904 50.55801 1.000 23.50333  ? 35  LEU A N     1 
ATOM   257  C  CA    . LEU A 1 42  ? -4.67528  -18.67483 50.46353 1.000 22.48195  ? 35  LEU A CA    1 
ATOM   258  C  C     . LEU A 1 42  ? -4.02241  -17.58880 51.29866 1.000 24.34978  ? 35  LEU A C     1 
ATOM   259  O  O     . LEU A 1 42  ? -3.92294  -17.73498 52.52693 1.000 24.34851  ? 35  LEU A O     1 
ATOM   260  C  CB    . LEU A 1 42  ? -6.09800  -18.96835 50.96798 1.000 23.12753  ? 35  LEU A CB    1 
ATOM   261  C  CG    . LEU A 1 42  ? -7.22755  -17.94252 50.78291 1.000 26.52078  ? 35  LEU A CG    1 
ATOM   262  C  CD1   . LEU A 1 42  ? -8.56304  -18.64410 50.93354 1.000 26.68553  ? 35  LEU A CD1   1 
ATOM   263  C  CD2   . LEU A 1 42  ? -7.13048  -16.76445 51.77373 1.000 28.42961  ? 35  LEU A CD2   1 
ATOM   264  N  N     . CYS A 1 43  ? -3.56809  -16.52323 50.63368 1.000 22.34808  ? 36  CYS A N     1 
ATOM   265  C  CA    . CYS A 1 43  ? -3.03276  -15.33491 51.28659 1.000 21.24298  ? 36  CYS A CA    1 
ATOM   266  C  C     . CYS A 1 43  ? -4.07661  -14.22804 51.20987 1.000 27.00338  ? 36  CYS A C     1 
ATOM   267  O  O     . CYS A 1 43  ? -4.58709  -13.93450 50.12658 1.000 25.00060  ? 36  CYS A O     1 
ATOM   268  C  CB    . CYS A 1 43  ? -1.74216  -14.87517 50.60061 1.000 20.29986  ? 36  CYS A CB    1 
ATOM   269  S  SG    . CYS A 1 43  ? -0.42329  -16.12896 50.59836 1.000 25.54956  ? 36  CYS A SG    1 
ATOM   270  N  N     . CYS A 1 44  ? -4.39266  -13.60290 52.33861 1.000 23.15301  ? 37  CYS A N     1 
ATOM   271  C  CA    . CYS A 1 44  ? -5.46190  -12.62389 52.30727 1.000 23.78313  ? 37  CYS A CA    1 
ATOM   272  C  C     . CYS A 1 44  ? -5.07084  -11.34443 53.03020 1.000 28.91140  ? 37  CYS A C     1 
ATOM   273  O  O     . CYS A 1 44  ? -4.21360  -11.32571 53.91721 1.000 29.30099  ? 37  CYS A O     1 
ATOM   274  C  CB    . CYS A 1 44  ? -6.75768  -13.18001 52.90266 1.000 29.63064  ? 37  CYS A CB    1 
ATOM   275  S  SG    . CYS A 1 44  ? -6.64052  -13.52305 54.63356 1.000 36.85148  ? 37  CYS A SG    1 
ATOM   276  N  N     . GLU A 1 45  ? -5.72689  -10.26368 52.61431 1.000 27.08461  ? 38  GLU A N     1 
ATOM   277  C  CA    . GLU A 1 45  ? -5.67839  -8.97639  53.28310 1.000 24.63839  ? 38  GLU A CA    1 
ATOM   278  C  C     . GLU A 1 45  ? -7.10194  -8.51421  53.50714 1.000 25.56536  ? 38  GLU A C     1 
ATOM   279  O  O     . GLU A 1 45  ? -7.94155  -8.64163  52.61397 1.000 26.26447  ? 38  GLU A O     1 
ATOM   280  C  CB    . GLU A 1 45  ? -4.96957  -7.91688  52.43963 1.000 30.34514  ? 38  GLU A CB    1 
ATOM   281  C  CG    . GLU A 1 45  ? -3.47592  -8.01824  52.37714 1.000 34.17978  ? 38  GLU A CG    1 
ATOM   282  C  CD    . GLU A 1 45  ? -2.88814  -6.88378  51.56380 1.000 39.10322  ? 38  GLU A CD    1 
ATOM   283  O  OE1   . GLU A 1 45  ? -2.60557  -5.82446  52.14861 1.000 41.39385  ? 38  GLU A OE1   1 
ATOM   284  O  OE2   . GLU A 1 45  ? -2.72761  -7.05259  50.33883 1.000 44.66092  ? 38  GLU A OE2   1 
ATOM   285  N  N     . VAL A 1 46  ? -7.35368  -7.94120  54.67879 1.000 23.77553  ? 39  VAL A N     1 
ATOM   286  C  CA    . VAL A 1 46  ? -8.60885  -7.26775  54.98771 1.000 27.26737  ? 39  VAL A CA    1 
ATOM   287  C  C     . VAL A 1 46  ? -8.33383  -5.77538  55.06174 1.000 30.55585  ? 39  VAL A C     1 
ATOM   288  O  O     . VAL A 1 46  ? -7.47519  -5.33317  55.83395 1.000 28.30020  ? 39  VAL A O     1 
ATOM   289  C  CB    . VAL A 1 46  ? -9.22078  -7.76897  56.30384 1.000 28.43840  ? 39  VAL A CB    1 
ATOM   290  C  CG1   . VAL A 1 46  ? -10.51717 -7.03353  56.57266 1.000 27.88883  ? 39  VAL A CG1   1 
ATOM   291  C  CG2   . VAL A 1 46  ? -9.46459  -9.26302  56.21294 1.000 25.29356  ? 39  VAL A CG2   1 
ATOM   292  N  N     . LYS A 1 47  ? -9.06892  -4.99973  54.27307 1.000 27.89619  ? 40  LYS A N     1 
ATOM   293  C  CA    . LYS A 1 47  ? -8.86026  -3.55861  54.18738 1.000 29.74137  ? 40  LYS A CA    1 
ATOM   294  C  C     . LYS A 1 47  ? -10.17679 -2.83276  54.41345 1.000 31.29038  ? 40  LYS A C     1 
ATOM   295  O  O     . LYS A 1 47  ? -11.25228 -3.43446  54.37978 1.000 28.06945  ? 40  LYS A O     1 
ATOM   296  C  CB    . LYS A 1 47  ? -8.25878  -3.18001  52.82289 1.000 28.01284  ? 40  LYS A CB    1 
ATOM   297  C  CG    . LYS A 1 47  ? -6.77735  -3.48837  52.73416 1.000 35.44590  ? 40  LYS A CG    1 
ATOM   298  C  CD    . LYS A 1 47  ? -6.22558  -3.33065  51.32453 1.000 49.95339  ? 40  LYS A CD    1 
ATOM   299  C  CE    . LYS A 1 47  ? -4.77056  -2.88502  51.35611 1.000 48.99084  ? 40  LYS A CE    1 
ATOM   300  N  NZ    . LYS A 1 47  ? -4.11208  -3.03081  50.02891 1.000 54.42601  ? 40  LYS A NZ    1 
ATOM   301  N  N     . THR A 1 48  ? -10.07924 -1.52413  54.67388 1.000 31.61089  ? 41  THR A N     1 
ATOM   302  C  CA    . THR A 1 48  ? -11.24267 -0.65552  54.71911 1.000 34.97457  ? 41  THR A CA    1 
ATOM   303  C  C     . THR A 1 48  ? -11.69578 -0.34985  53.29558 1.000 39.38792  ? 41  THR A C     1 
ATOM   304  O  O     . THR A 1 48  ? -11.11002 -0.81988  52.32374 1.000 32.61045  ? 41  THR A O     1 
ATOM   305  C  CB    . THR A 1 48  ? -10.91693 0.65151   55.44715 1.000 39.13038  ? 41  THR A CB    1 
ATOM   306  O  OG1   . THR A 1 48  ? -9.86784  1.32332   54.73618 1.000 32.40106  ? 41  THR A OG1   1 
ATOM   307  C  CG2   . THR A 1 48  ? -10.45146 0.38010   56.87242 1.000 33.39799  ? 41  THR A CG2   1 
ATOM   308  N  N     . LYS A 1 49  ? -12.72973 0.48607   53.16499 1.000 40.49732  ? 42  LYS A N     1 
ATOM   309  C  CA    . LYS A 1 49  ? -13.11651 0.95945   51.83984 1.000 49.54280  ? 42  LYS A CA    1 
ATOM   310  C  C     . LYS A 1 49  ? -12.00540 1.76289   51.17841 1.000 52.79400  ? 42  LYS A C     1 
ATOM   311  O  O     . LYS A 1 49  ? -11.88099 1.74447   49.94837 1.000 52.53643  ? 42  LYS A O     1 
ATOM   312  C  CB    . LYS A 1 49  ? -14.39687 1.79111   51.90871 1.000 56.85520  ? 42  LYS A CB    1 
ATOM   313  C  CG    . LYS A 1 49  ? -15.62153 1.00648   51.47956 1.000 67.80475  ? 42  LYS A CG    1 
ATOM   314  C  CD    . LYS A 1 49  ? -16.77434 1.91199   51.09490 1.000 67.89018  ? 42  LYS A CD    1 
ATOM   315  C  CE    . LYS A 1 49  ? -17.89841 1.10059   50.46388 1.000 69.66268  ? 42  LYS A CE    1 
ATOM   316  N  NZ    . LYS A 1 49  ? -19.03719 1.94916   50.00021 1.000 70.07313  ? 42  LYS A NZ    1 
ATOM   317  N  N     . ASP A 1 50  ? -11.19678 2.46385   51.96419 1.000 57.11468  ? 43  ASP A N     1 
ATOM   318  C  CA    . ASP A 1 50  ? -10.01489 3.13443   51.43405 1.000 66.45126  ? 43  ASP A CA    1 
ATOM   319  C  C     . ASP A 1 50  ? -8.87546  2.13068   51.29385 1.000 67.05094  ? 43  ASP A C     1 
ATOM   320  O  O     . ASP A 1 50  ? -8.39411  1.61117   52.30735 1.000 67.43805  ? 43  ASP A O     1 
ATOM   321  C  CB    . ASP A 1 50  ? -9.60193  4.28334   52.34248 1.000 66.57168  ? 43  ASP A CB    1 
ATOM   322  C  CG    . ASP A 1 50  ? -8.94606  5.40972   51.58215 1.000 79.85928  ? 43  ASP A CG    1 
ATOM   323  O  OD1   . ASP A 1 50  ? -7.89992  5.14554   50.95022 1.000 84.99004  ? 43  ASP A OD1   1 
ATOM   324  O  OD2   . ASP A 1 50  ? -9.46563  6.54720   51.61372 1.000 84.91590  ? 43  ASP A OD2   1 
ATOM   325  N  N     . PRO A 1 51  ? -8.41339  1.83554   50.07923 1.000 88.40790  ? 44  PRO A N     1 
ATOM   326  C  CA    . PRO A 1 51  ? -7.52281  0.68098   49.89134 1.000 92.60093  ? 44  PRO A CA    1 
ATOM   327  C  C     . PRO A 1 51  ? -6.04533  0.98982   50.08363 1.000 98.20525  ? 44  PRO A C     1 
ATOM   328  O  O     . PRO A 1 51  ? -5.25721  0.08349   50.37864 1.000 87.74667  ? 44  PRO A O     1 
ATOM   329  C  CB    . PRO A 1 51  ? -7.80407  0.25826   48.43834 1.000 88.05350  ? 44  PRO A CB    1 
ATOM   330  C  CG    . PRO A 1 51  ? -8.93869  1.17017   47.94782 1.000 85.61042  ? 44  PRO A CG    1 
ATOM   331  C  CD    . PRO A 1 51  ? -8.83391  2.39842   48.78919 1.000 83.24252  ? 44  PRO A CD    1 
ATOM   332  N  N     . SER A 1 52  ? -5.65966  2.25894   49.91920 1.000 92.63582  ? 45  SER A N     1 
ATOM   333  C  CA    . SER A 1 52  ? -4.24256  2.59526   49.79294 1.000 89.86520  ? 45  SER A CA    1 
ATOM   334  C  C     . SER A 1 52  ? -3.46642  2.26262   51.06234 1.000 92.26385  ? 45  SER A C     1 
ATOM   335  O  O     . SER A 1 52  ? -2.37733  1.67852   50.99964 1.000 91.82788  ? 45  SER A O     1 
ATOM   336  C  CB    . SER A 1 52  ? -4.08268  4.07191   49.43104 1.000 89.69104  ? 45  SER A CB    1 
ATOM   337  O  OG    . SER A 1 52  ? -4.11092  4.25017   48.02521 1.000 85.24501  ? 45  SER A OG    1 
ATOM   338  N  N     . GLY A 1 53  ? -4.01196  2.62071   52.22372 1.000 89.94474  ? 46  GLY A N     1 
ATOM   339  C  CA    . GLY A 1 53  ? -3.34263  2.39552   53.48390 1.000 83.74999  ? 46  GLY A CA    1 
ATOM   340  C  C     . GLY A 1 53  ? -3.06473  0.93085   53.75854 1.000 77.30756  ? 46  GLY A C     1 
ATOM   341  O  O     . GLY A 1 53  ? -3.55478  0.03555   53.06114 1.000 78.37429  ? 46  GLY A O     1 
ATOM   342  N  N     . PRO A 1 54  ? -2.26567  0.66225   54.78942 1.000 63.74681  ? 47  PRO A N     1 
ATOM   343  C  CA    . PRO A 1 54  ? -1.93985  -0.72112  55.11448 1.000 55.78198  ? 47  PRO A CA    1 
ATOM   344  C  C     . PRO A 1 54  ? -3.18888  -1.47986  55.51500 1.000 46.18423  ? 47  PRO A C     1 
ATOM   345  O  O     . PRO A 1 54  ? -4.17582  -0.88283  55.98395 1.000 41.98167  ? 47  PRO A O     1 
ATOM   346  C  CB    . PRO A 1 54  ? -0.95844  -0.58391  56.28722 1.000 62.62539  ? 47  PRO A CB    1 
ATOM   347  C  CG    . PRO A 1 54  ? -1.33143  0.71149   56.91443 1.000 59.66500  ? 47  PRO A CG    1 
ATOM   348  C  CD    . PRO A 1 54  ? -1.67588  1.60521   55.75456 1.000 60.57452  ? 47  PRO A CD    1 
ATOM   349  N  N     . PRO A 1 55  ? -3.19536  -2.79751  55.34517 1.000 44.10155  ? 48  PRO A N     1 
ATOM   350  C  CA    . PRO A 1 55  ? -4.39814  -3.56432  55.66805 1.000 37.93975  ? 48  PRO A CA    1 
ATOM   351  C  C     . PRO A 1 55  ? -4.67280  -3.54617  57.16234 1.000 31.46886  ? 48  PRO A C     1 
ATOM   352  O  O     . PRO A 1 55  ? -3.78768  -3.30760  57.99170 1.000 31.87933  ? 48  PRO A O     1 
ATOM   353  C  CB    . PRO A 1 55  ? -4.05512  -4.97634  55.18917 1.000 34.27152  ? 48  PRO A CB    1 
ATOM   354  C  CG    . PRO A 1 55  ? -2.57240  -5.03800  55.34636 1.000 41.19068  ? 48  PRO A CG    1 
ATOM   355  C  CD    . PRO A 1 55  ? -2.08413  -3.67519  54.94085 1.000 44.75652  ? 48  PRO A CD    1 
ATOM   356  N  N     . LEU A 1 56  ? -5.93681  -3.80230  57.50413 1.000 29.55809  ? 49  LEU A N     1 
ATOM   357  C  CA    . LEU A 1 56  ? -6.28254  -3.95981  58.91476 1.000 28.65398  ? 49  LEU A CA    1 
ATOM   358  C  C     . LEU A 1 56  ? -5.71108  -5.25646  59.47208 1.000 28.82972  ? 49  LEU A C     1 
ATOM   359  O  O     . LEU A 1 56  ? -5.30287  -5.30663  60.63488 1.000 30.46856  ? 49  LEU A O     1 
ATOM   360  C  CB    . LEU A 1 56  ? -7.80006  -3.92376  59.08705 1.000 32.35780  ? 49  LEU A CB    1 
ATOM   361  C  CG    . LEU A 1 56  ? -8.51459  -2.63979  58.64724 1.000 32.56898  ? 49  LEU A CG    1 
ATOM   362  C  CD1   . LEU A 1 56  ? -10.01905 -2.80738  58.72727 1.000 38.75049  ? 49  LEU A CD1   1 
ATOM   363  C  CD2   . LEU A 1 56  ? -8.06694  -1.45341  59.50767 1.000 29.80958  ? 49  LEU A CD2   1 
ATOM   364  N  N     . ASP A 1 57  ? -5.65429  -6.29836  58.65015 1.000 29.78649  ? 50  ASP A N     1 
ATOM   365  C  CA    . ASP A 1 57  ? -5.09286  -7.58344  59.05033 1.000 29.13829  ? 50  ASP A CA    1 
ATOM   366  C  C     . ASP A 1 57  ? -4.73373  -8.34843  57.78790 1.000 26.14490  ? 50  ASP A C     1 
ATOM   367  O  O     . ASP A 1 57  ? -5.16223  -8.00496  56.67829 1.000 28.89917  ? 50  ASP A O     1 
ATOM   368  C  CB    . ASP A 1 57  ? -6.06861  -8.38426  59.92917 1.000 29.06513  ? 50  ASP A CB    1 
ATOM   369  C  CG    . ASP A 1 57  ? -5.36327  -9.24716  60.97854 1.000 33.49120  ? 50  ASP A CG    1 
ATOM   370  O  OD1   . ASP A 1 57  ? -4.15830  -9.53997  60.84478 1.000 34.42045  ? 50  ASP A OD1   1 
ATOM   371  O  OD2   . ASP A 1 57  ? -6.02066  -9.60940  61.97401 1.000 35.08769  ? 50  ASP A OD2   1 
ATOM   372  N  N     . ALA A 1 58  ? -3.92035  -9.38100  57.96989 1.000 26.36190  ? 51  ALA A N     1 
ATOM   373  C  CA    . ALA A 1 58  ? -3.51979  -10.23551 56.86221 1.000 26.10342  ? 51  ALA A CA    1 
ATOM   374  C  C     . ALA A 1 58  ? -3.23486  -11.61048 57.43292 1.000 25.53741  ? 51  ALA A C     1 
ATOM   375  O  O     . ALA A 1 58  ? -2.79221  -11.73524 58.58073 1.000 26.00963  ? 51  ALA A O     1 
ATOM   376  C  CB    . ALA A 1 58  ? -2.29247  -9.67921  56.13810 1.000 30.84111  ? 51  ALA A CB    1 
ATOM   377  N  N     . LYS A 1 59  ? -3.50993  -12.64289 56.63756 1.000 25.51113  ? 52  LYS A N     1 
ATOM   378  C  CA    . LYS A 1 59  ? -3.38796  -14.00693 57.12360 1.000 25.92541  ? 52  LYS A CA    1 
ATOM   379  C  C     . LYS A 1 59  ? -3.00729  -14.92912 55.97291 1.000 28.44427  ? 52  LYS A C     1 
ATOM   380  O  O     . LYS A 1 59  ? -3.28981  -14.63781 54.80799 1.000 28.69712  ? 52  LYS A O     1 
ATOM   381  C  CB    . LYS A 1 59  ? -4.69659  -14.48001 57.76500 1.000 30.80128  ? 52  LYS A CB    1 
ATOM   382  C  CG    . LYS A 1 59  ? -4.85417  -14.03690 59.21660 1.000 40.11867  ? 52  LYS A CG    1 
ATOM   383  C  CD    . LYS A 1 59  ? -4.93274  -15.25215 60.13595 1.000 43.42724  ? 52  LYS A CD    1 
ATOM   384  C  CE    . LYS A 1 59  ? -5.09002  -14.83993 61.59463 1.000 48.53001  ? 52  LYS A CE    1 
ATOM   385  N  NZ    . LYS A 1 59  ? -4.02657  -13.90780 62.08391 1.000 48.41660  ? 52  LYS A NZ    1 
ATOM   386  N  N     . ILE A 1 60  ? -2.36882  -16.04817 56.31237 1.000 26.49060  ? 53  ILE A N     1 
ATOM   387  C  CA    . ILE A 1 60  ? -2.08608  -17.11460 55.35126 1.000 25.53750  ? 53  ILE A CA    1 
ATOM   388  C  C     . ILE A 1 60  ? -2.79581  -18.36317 55.84900 1.000 27.01770  ? 53  ILE A C     1 
ATOM   389  O  O     . ILE A 1 60  ? -2.60052  -18.77582 56.99943 1.000 28.32669  ? 53  ILE A O     1 
ATOM   390  C  CB    . ILE A 1 60  ? -0.57734  -17.36287 55.17819 1.000 25.76108  ? 53  ILE A CB    1 
ATOM   391  C  CG1   . ILE A 1 60  ? 0.11941   -16.15444 54.56326 1.000 31.28682  ? 53  ILE A CG1   1 
ATOM   392  C  CG2   . ILE A 1 60  ? -0.31027  -18.62986 54.34099 1.000 29.96865  ? 53  ILE A CG2   1 
ATOM   393  C  CD1   . ILE A 1 60  ? 1.61404   -16.15719 54.78545 1.000 27.80741  ? 53  ILE A CD1   1 
ATOM   394  N  N     . PHE A 1 61  ? -3.64805  -18.93636 55.00412 1.000 23.93615  ? 54  PHE A N     1 
ATOM   395  C  CA    . PHE A 1 61  ? -4.38742  -20.15259 55.31074 1.000 24.93400  ? 54  PHE A CA    1 
ATOM   396  C  C     . PHE A 1 61  ? -3.97687  -21.24945 54.34639 1.000 29.76712  ? 54  PHE A C     1 
ATOM   397  O  O     . PHE A 1 61  ? -3.72078  -20.99038 53.16857 1.000 21.98706  ? 54  PHE A O     1 
ATOM   398  C  CB    . PHE A 1 61  ? -5.90251  -19.94206 55.20836 1.000 26.94007  ? 54  PHE A CB    1 
ATOM   399  C  CG    . PHE A 1 61  ? -6.45877  -19.03614 56.26881 1.000 30.97900  ? 54  PHE A CG    1 
ATOM   400  C  CD1   . PHE A 1 61  ? -6.68442  -19.50730 57.55992 1.000 28.18315  ? 54  PHE A CD1   1 
ATOM   401  C  CD2   . PHE A 1 61  ? -6.72852  -17.70077 55.98536 1.000 31.15360  ? 54  PHE A CD2   1 
ATOM   402  C  CE1   . PHE A 1 61  ? -7.19200  -18.66295 58.54838 1.000 29.51116  ? 54  PHE A CE1   1 
ATOM   403  C  CE2   . PHE A 1 61  ? -7.23078  -16.86395 56.95862 1.000 25.81015  ? 54  PHE A CE2   1 
ATOM   404  C  CZ    . PHE A 1 61  ? -7.46076  -17.34185 58.24288 1.000 26.62817  ? 54  PHE A CZ    1 
ATOM   405  N  N     . GLN A 1 62  ? -3.93327  -22.47946 54.84346 1.000 25.95291  ? 55  GLN A N     1 
ATOM   406  C  CA    . GLN A 1 62  ? -3.63107  -23.61492 53.98811 1.000 27.34709  ? 55  GLN A CA    1 
ATOM   407  C  C     . GLN A 1 62  ? -4.57544  -24.74663 54.34959 1.000 27.26510  ? 55  GLN A C     1 
ATOM   408  O  O     . GLN A 1 62  ? -5.08343  -24.82412 55.46972 1.000 30.86432  ? 55  GLN A O     1 
ATOM   409  C  CB    . GLN A 1 62  ? -2.17641  -24.06938 54.13866 1.000 28.56992  ? 55  GLN A CB    1 
ATOM   410  C  CG    . GLN A 1 62  ? -1.81919  -24.50361 55.54933 1.000 38.61268  ? 55  GLN A CG    1 
ATOM   411  C  CD    . GLN A 1 62  ? -0.55643  -25.34282 55.58875 1.000 36.39811  ? 55  GLN A CD    1 
ATOM   412  O  OE1   . GLN A 1 62  ? -0.46907  -26.37867 54.92768 1.000 37.31393  ? 55  GLN A OE1   1 
ATOM   413  N  NE2   . GLN A 1 62  ? 0.42197   -24.90887 56.37372 1.000 45.41859  ? 55  GLN A NE2   1 
ATOM   414  N  N     . GLY A 1 63  ? -4.80520  -25.63382 53.39550 1.000 24.93275  ? 56  GLY A N     1 
ATOM   415  C  CA    . GLY A 1 63  ? -5.62501  -26.79259 53.68383 1.000 30.80277  ? 56  GLY A CA    1 
ATOM   416  C  C     . GLY A 1 63  ? -5.43996  -27.87128 52.64782 1.000 30.18156  ? 56  GLY A C     1 
ATOM   417  O  O     . GLY A 1 63  ? -5.27523  -27.56889 51.46464 1.000 26.15199  ? 56  GLY A O     1 
ATOM   418  N  N     . LYS A 1 64  ? -5.44310  -29.13174 53.06977 1.000 28.23115  ? 57  LYS A N     1 
ATOM   419  C  CA    . LYS A 1 64  ? -5.29906  -30.22659 52.11372 1.000 29.88161  ? 57  LYS A CA    1 
ATOM   420  C  C     . LYS A 1 64  ? -6.50894  -30.28803 51.18753 1.000 30.60814  ? 57  LYS A C     1 
ATOM   421  O  O     . LYS A 1 64  ? -7.64902  -30.10379 51.61998 1.000 28.42295  ? 57  LYS A O     1 
ATOM   422  C  CB    . LYS A 1 64  ? -5.13526  -31.55788 52.85521 1.000 34.52021  ? 57  LYS A CB    1 
ATOM   423  C  CG    . LYS A 1 64  ? -3.86491  -31.64428 53.69661 1.000 37.39832  ? 57  LYS A CG    1 
ATOM   424  C  CD    . LYS A 1 64  ? -2.62375  -31.69645 52.81179 1.000 41.19867  ? 57  LYS A CD    1 
ATOM   425  C  CE    . LYS A 1 64  ? -1.33769  -31.54542 53.62021 1.000 49.36050  ? 57  LYS A CE    1 
ATOM   426  N  NZ    . LYS A 1 64  ? -0.86015  -30.12994 53.66360 1.000 49.05985  ? 57  LYS A NZ    1 
ATOM   427  N  N     . VAL A 1 65  ? -6.26854  -30.56012 49.90024 1.000 26.72360  ? 58  VAL A N     1 
ATOM   428  C  CA    . VAL A 1 65  ? -7.39174  -30.62544 48.96750 1.000 29.03227  ? 58  VAL A CA    1 
ATOM   429  C  C     . VAL A 1 65  ? -8.34864  -31.74750 49.34923 1.000 31.44244  ? 58  VAL A C     1 
ATOM   430  O  O     . VAL A 1 65  ? -9.57224  -31.59176 49.27211 1.000 36.30610  ? 58  VAL A O     1 
ATOM   431  C  CB    . VAL A 1 65  ? -6.90215  -30.77798 47.51716 1.000 40.97142  ? 58  VAL A CB    1 
ATOM   432  C  CG1   . VAL A 1 65  ? -8.09548  -30.75330 46.58232 1.000 40.71354  ? 58  VAL A CG1   1 
ATOM   433  C  CG2   . VAL A 1 65  ? -5.96899  -29.64224 47.15896 1.000 35.19661  ? 58  VAL A CG2   1 
ATOM   434  N  N     . TYR A 1 66  ? -7.81207  -32.88994 49.76751 1.000 30.29324  ? 59  TYR A N     1 
ATOM   435  C  CA    . TYR A 1 66  ? -8.58539  -34.06421 50.15958 1.000 36.74389  ? 59  TYR A CA    1 
ATOM   436  C  C     . TYR A 1 66  ? -8.24705  -34.43575 51.59621 1.000 33.05760  ? 59  TYR A C     1 
ATOM   437  O  O     . TYR A 1 66  ? -7.09985  -34.26150 52.02438 1.000 31.66211  ? 59  TYR A O     1 
ATOM   438  C  CB    . TYR A 1 66  ? -8.29143  -35.23810 49.21528 1.000 29.91023  ? 59  TYR A CB    1 
ATOM   439  C  CG    . TYR A 1 66  ? -8.75250  -34.94314 47.80480 1.000 38.11737  ? 59  TYR A CG    1 
ATOM   440  C  CD1   . TYR A 1 66  ? -10.10622 -34.78497 47.51418 1.000 42.41206  ? 59  TYR A CD1   1 
ATOM   441  C  CD2   . TYR A 1 66  ? -7.83437  -34.70427 46.79152 1.000 32.14298  ? 59  TYR A CD2   1 
ATOM   442  C  CE1   . TYR A 1 66  ? -10.53750 -34.48843 46.22716 1.000 41.67388  ? 59  TYR A CE1   1 
ATOM   443  C  CE2   . TYR A 1 66  ? -8.25093  -34.38586 45.50422 1.000 32.96273  ? 59  TYR A CE2   1 
ATOM   444  C  CZ    . TYR A 1 66  ? -9.60389  -34.28358 45.22655 1.000 42.51358  ? 59  TYR A CZ    1 
ATOM   445  O  OH    . TYR A 1 66  ? -10.02095 -33.96308 43.94862 1.000 35.37815  ? 59  TYR A OH    1 
ATOM   446  N  N     . PRO A 1 67  ? -9.21635  -34.96551 52.36820 1.000 40.57938  ? 60  PRO A N     1 
ATOM   447  C  CA    . PRO A 1 67  ? -10.53865 -35.45027 51.95310 1.000 39.82051  ? 60  PRO A CA    1 
ATOM   448  C  C     . PRO A 1 67  ? -11.73393 -34.48831 52.05317 1.000 46.36932  ? 60  PRO A C     1 
ATOM   449  O  O     . PRO A 1 67  ? -12.72662 -34.73375 51.36310 1.000 54.02739  ? 60  PRO A O     1 
ATOM   450  C  CB    . PRO A 1 67  ? -10.74607 -36.62890 52.90622 1.000 49.70884  ? 60  PRO A CB    1 
ATOM   451  C  CG    . PRO A 1 67  ? -10.16699 -36.11310 54.20518 1.000 46.58086  ? 60  PRO A CG    1 
ATOM   452  C  CD    . PRO A 1 67  ? -9.03916  -35.13893 53.82307 1.000 44.73660  ? 60  PRO A CD    1 
ATOM   453  N  N     . LYS A 1 68  ? -11.66567 -33.43444 52.86803 1.000 44.58501  ? 61  LYS A N     1 
ATOM   454  C  CA    . LYS A 1 68  ? -12.85397 -32.65103 53.18807 1.000 44.20421  ? 61  LYS A CA    1 
ATOM   455  C  C     . LYS A 1 68  ? -12.65490 -31.18373 52.85135 1.000 45.86095  ? 61  LYS A C     1 
ATOM   456  O  O     . LYS A 1 68  ? -11.69566 -30.56119 53.31588 1.000 38.49450  ? 61  LYS A O     1 
ATOM   457  C  CB    . LYS A 1 68  ? -13.22652 -32.79921 54.66276 1.000 51.37981  ? 61  LYS A CB    1 
ATOM   458  C  CG    . LYS A 1 68  ? -13.95065 -34.10254 54.95636 1.000 60.79168  ? 61  LYS A CG    1 
ATOM   459  C  CD    . LYS A 1 68  ? -15.10521 -34.32486 53.97417 1.000 56.80303  ? 61  LYS A CD    1 
ATOM   460  C  CE    . LYS A 1 68  ? -15.41860 -35.80857 53.81330 1.000 69.64011  ? 61  LYS A CE    1 
ATOM   461  N  NZ    . LYS A 1 68  ? -16.87888 -36.10246 53.90687 1.000 76.93091  ? 61  LYS A NZ    1 
ATOM   462  N  N     . ALA A 1 69  ? -13.58651 -30.63639 52.06205 1.000 40.80182  ? 62  ALA A N     1 
ATOM   463  C  CA    . ALA A 1 69  ? -13.56035 -29.22478 51.70347 1.000 38.42950  ? 62  ALA A CA    1 
ATOM   464  C  C     . ALA A 1 69  ? -13.71006 -28.31576 52.91092 1.000 39.78341  ? 62  ALA A C     1 
ATOM   465  O  O     . ALA A 1 69  ? -13.32588 -27.14275 52.83728 1.000 39.91698  ? 62  ALA A O     1 
ATOM   466  C  CB    . ALA A 1 69  ? -14.66634 -28.91680 50.69251 1.000 44.25001  ? 62  ALA A CB    1 
ATOM   467  N  N     . LYS A 1 70  ? -14.26097 -28.82047 54.02030 1.000 45.12426  ? 63  LYS A N     1 
ATOM   468  C  CA    . LYS A 1 70  ? -14.46215 -27.96508 55.18338 1.000 43.37116  ? 63  LYS A CA    1 
ATOM   469  C  C     . LYS A 1 70  ? -13.14100 -27.49712 55.78004 1.000 39.43166  ? 63  LYS A C     1 
ATOM   470  O  O     . LYS A 1 70  ? -13.13045 -26.51968 56.53322 1.000 36.03636  ? 63  LYS A O     1 
ATOM   471  C  CB    . LYS A 1 70  ? -15.29642 -28.68917 56.24206 1.000 42.22969  ? 63  LYS A CB    1 
ATOM   472  C  CG    . LYS A 1 70  ? -14.49465 -29.60489 57.12077 1.000 47.96262  ? 63  LYS A CG    1 
ATOM   473  C  CD    . LYS A 1 70  ? -15.37396 -30.54766 57.93977 1.000 63.78772  ? 63  LYS A CD    1 
ATOM   474  C  CE    . LYS A 1 70  ? -16.04857 -31.59337 57.06031 1.000 65.75713  ? 63  LYS A CE    1 
ATOM   475  N  NZ    . LYS A 1 70  ? -16.06848 -32.93589 57.71663 1.000 70.64339  ? 63  LYS A NZ    1 
ATOM   476  N  N     . TYR A 1 71  ? -12.02864 -28.16024 55.45579 1.000 37.47641  ? 64  TYR A N     1 
ATOM   477  C  CA    . TYR A 1 71  ? -10.71102 -27.70166 55.87228 1.000 33.31655  ? 64  TYR A CA    1 
ATOM   478  C  C     . TYR A 1 71  ? -9.93031  -27.04552 54.73983 1.000 31.81435  ? 64  TYR A C     1 
ATOM   479  O  O     . TYR A 1 71  ? -8.73172  -26.79414 54.89099 1.000 33.38695  ? 64  TYR A O     1 
ATOM   480  C  CB    . TYR A 1 71  ? -9.90213  -28.84622 56.48650 1.000 33.20314  ? 64  TYR A CB    1 
ATOM   481  C  CG    . TYR A 1 71  ? -10.56740 -29.43467 57.71389 1.000 50.11742  ? 64  TYR A CG    1 
ATOM   482  C  CD1   . TYR A 1 71  ? -11.33335 -30.58941 57.63029 1.000 51.37643  ? 64  TYR A CD1   1 
ATOM   483  C  CD2   . TYR A 1 71  ? -10.48274 -28.79118 58.94709 1.000 58.96770  ? 64  TYR A CD2   1 
ATOM   484  C  CE1   . TYR A 1 71  ? -11.95465 -31.12487 58.75710 1.000 59.86043  ? 64  TYR A CE1   1 
ATOM   485  C  CE2   . TYR A 1 71  ? -11.10593 -29.31114 60.07402 1.000 62.54539  ? 64  TYR A CE2   1 
ATOM   486  C  CZ    . TYR A 1 71  ? -11.84255 -30.47669 59.97226 1.000 62.97690  ? 64  TYR A CZ    1 
ATOM   487  O  OH    . TYR A 1 71  ? -12.46449 -30.99705 61.08997 1.000 68.41903  ? 64  TYR A OH    1 
ATOM   488  N  N     . HIS A 1 72  ? -10.57606 -26.75204 53.61692 1.000 29.25338  ? 65  HIS A N     1 
ATOM   489  C  CA    . HIS A 1 72  ? -9.93397  -25.94182 52.59882 1.000 24.62793  ? 65  HIS A CA    1 
ATOM   490  C  C     . HIS A 1 72  ? -9.73181  -24.52210 53.13383 1.000 29.50891  ? 65  HIS A C     1 
ATOM   491  O  O     . HIS A 1 72  ? -10.48404 -24.06862 53.99981 1.000 25.40436  ? 65  HIS A O     1 
ATOM   492  C  CB    . HIS A 1 72  ? -10.77648 -25.93566 51.33158 1.000 26.33855  ? 65  HIS A CB    1 
ATOM   493  C  CG    . HIS A 1 72  ? -10.72827 -27.23602 50.58773 1.000 31.63100  ? 65  HIS A CG    1 
ATOM   494  N  ND1   . HIS A 1 72  ? -11.43882 -27.46451 49.43520 1.000 30.34707  ? 65  HIS A ND1   1 
ATOM   495  C  CD2   . HIS A 1 72  ? -10.05459 -28.38257 50.83951 1.000 33.70912  ? 65  HIS A CD2   1 
ATOM   496  C  CE1   . HIS A 1 72  ? -11.20959 -28.68956 48.99717 1.000 36.08348  ? 65  HIS A CE1   1 
ATOM   497  N  NE2   . HIS A 1 72  ? -10.37121 -29.27103 49.83447 1.000 33.90006  ? 65  HIS A NE2   1 
ATOM   498  N  N     . PRO A 1 73  ? -8.69800  -23.81808 52.66934 1.000 25.13758  ? 66  PRO A N     1 
ATOM   499  C  CA    . PRO A 1 73  ? -8.38587  -22.50981 53.27696 1.000 25.60897  ? 66  PRO A CA    1 
ATOM   500  C  C     . PRO A 1 73  ? -9.51166  -21.48530 53.13991 1.000 27.36252  ? 66  PRO A C     1 
ATOM   501  O  O     . PRO A 1 73  ? -9.60879  -20.58400 53.98364 1.000 25.78746  ? 66  PRO A O     1 
ATOM   502  C  CB    . PRO A 1 73  ? -7.11151  -22.07456 52.53780 1.000 24.01432  ? 66  PRO A CB    1 
ATOM   503  C  CG    . PRO A 1 73  ? -7.16632  -22.81115 51.19474 1.000 23.86779  ? 66  PRO A CG    1 
ATOM   504  C  CD    . PRO A 1 73  ? -7.78334  -24.15419 51.56122 1.000 25.32728  ? 66  PRO A CD    1 
ATOM   505  N  N     . GLU A 1 74  ? -10.37377 -21.60871 52.11824 1.000 29.46269  ? 67  GLU A N     1 
ATOM   506  C  CA    . GLU A 1 74  ? -11.53791 -20.72672 51.99876 1.000 24.94793  ? 67  GLU A CA    1 
ATOM   507  C  C     . GLU A 1 74  ? -12.44630 -20.82625 53.22005 1.000 29.37990  ? 67  GLU A C     1 
ATOM   508  O  O     . GLU A 1 74  ? -12.93254 -19.80963 53.72349 1.000 24.03965  ? 67  GLU A O     1 
ATOM   509  C  CB    . GLU A 1 74  ? -12.33706 -21.06311 50.73918 1.000 27.89161  ? 67  GLU A CB    1 
ATOM   510  C  CG    . GLU A 1 74  ? -11.55527 -20.97152 49.43556 1.000 23.71213  ? 67  GLU A CG    1 
ATOM   511  C  CD    . GLU A 1 74  ? -11.00096 -22.30486 48.98304 1.000 31.71606  ? 67  GLU A CD    1 
ATOM   512  O  OE1   . GLU A 1 74  ? -10.32380 -22.98334 49.78715 1.000 24.89131  ? 67  GLU A OE1   1 
ATOM   513  O  OE2   . GLU A 1 74  ? -11.22609 -22.65989 47.81508 1.000 27.98129  ? 67  GLU A OE2   1 
ATOM   514  N  N     . MET A 1 75  ? -12.71959 -22.04746 53.68632 1.000 23.04414  ? 68  MET A N     1 
ATOM   515  C  CA    . MET A 1 75  ? -13.55586 -22.22179 54.87423 1.000 28.33168  ? 68  MET A CA    1 
ATOM   516  C  C     . MET A 1 75  ? -12.83101 -21.79421 56.14396 1.000 26.21886  ? 68  MET A C     1 
ATOM   517  O  O     . MET A 1 75  ? -13.45393 -21.25247 57.06579 1.000 27.70168  ? 68  MET A O     1 
ATOM   518  C  CB    . MET A 1 75  ? -14.01209 -23.68115 54.98149 1.000 30.57583  ? 68  MET A CB    1 
ATOM   519  C  CG    . MET A 1 75  ? -14.80158 -24.21873 53.78722 1.000 28.04803  ? 68  MET A CG    1 
ATOM   520  S  SD    . MET A 1 75  ? -16.14243 -23.12629 53.25300 1.000 34.71833  ? 68  MET A SD    1 
ATOM   521  C  CE    . MET A 1 75  ? -17.46452 -23.60479 54.35437 1.000 48.28658  ? 68  MET A CE    1 
ATOM   522  N  N     . ARG A 1 76  ? -11.52417 -22.05846 56.23352 1.000 29.35322  ? 69  ARG A N     1 
ATOM   523  C  CA    . ARG A 1 76  ? -10.75676 -21.54527 57.36470 1.000 26.02662  ? 69  ARG A CA    1 
ATOM   524  C  C     . ARG A 1 76  ? -10.82217 -20.02750 57.41785 1.000 25.66482  ? 69  ARG A C     1 
ATOM   525  O  O     . ARG A 1 76  ? -10.96422 -19.44221 58.50143 1.000 24.30498  ? 69  ARG A O     1 
ATOM   526  C  CB    . ARG A 1 76  ? -9.30586  -22.01439 57.28548 1.000 23.88831  ? 69  ARG A CB    1 
ATOM   527  C  CG    . ARG A 1 76  ? -9.15733  -23.54676 57.36423 1.000 34.05107  ? 69  ARG A CG    1 
ATOM   528  C  CD    . ARG A 1 76  ? -7.69618  -23.96933 57.30047 1.000 36.07091  ? 69  ARG A CD    1 
ATOM   529  N  NE    . ARG A 1 76  ? -7.52873  -25.41702 57.22964 1.000 35.63820  ? 69  ARG A NE    1 
ATOM   530  C  CZ    . ARG A 1 76  ? -7.12394  -26.16939 58.24360 1.000 49.67326  ? 69  ARG A CZ    1 
ATOM   531  N  NH1   . ARG A 1 76  ? -6.91162  -25.65149 59.44416 1.000 47.41760  ? 69  ARG A NH1   1 
ATOM   532  N  NH2   . ARG A 1 76  ? -6.93494  -27.47425 58.05100 1.000 41.62071  ? 69  ARG A NH2   1 
ATOM   533  N  N     . PHE A 1 77  ? -10.71318 -19.37656 56.25781 1.000 24.38242  ? 70  PHE A N     1 
ATOM   534  C  CA    . PHE A 1 77  ? -10.85506 -17.92570 56.20272 1.000 22.55157  ? 70  PHE A CA    1 
ATOM   535  C  C     . PHE A 1 77  ? -12.19935 -17.48758 56.76273 1.000 25.18195  ? 70  PHE A C     1 
ATOM   536  O  O     . PHE A 1 77  ? -12.27215 -16.57991 57.60324 1.000 27.63841  ? 70  PHE A O     1 
ATOM   537  C  CB    . PHE A 1 77  ? -10.72473 -17.40599 54.76569 1.000 21.39462  ? 70  PHE A CB    1 
ATOM   538  C  CG    . PHE A 1 77  ? -11.07648 -15.94478 54.65633 1.000 25.02169  ? 70  PHE A CG    1 
ATOM   539  C  CD1   . PHE A 1 77  ? -10.12916 -14.98196 54.94553 1.000 25.43008  ? 70  PHE A CD1   1 
ATOM   540  C  CD2   . PHE A 1 77  ? -12.37707 -15.53946 54.38656 1.000 25.85509  ? 70  PHE A CD2   1 
ATOM   541  C  CE1   . PHE A 1 77  ? -10.44858 -13.64033 54.89820 1.000 29.76637  ? 70  PHE A CE1   1 
ATOM   542  C  CE2   . PHE A 1 77  ? -12.70670 -14.18615 54.35566 1.000 25.22560  ? 70  PHE A CE2   1 
ATOM   543  C  CZ    . PHE A 1 77  ? -11.73637 -13.24325 54.61023 1.000 28.85867  ? 70  PHE A CZ    1 
ATOM   544  N  N     . LEU A 1 78  ? -13.28593 -18.08828 56.26429 1.000 26.63148  ? 71  LEU A N     1 
ATOM   545  C  CA    . LEU A 1 78  ? -14.62169 -17.66447 56.68424 1.000 27.84522  ? 71  LEU A CA    1 
ATOM   546  C  C     . LEU A 1 78  ? -14.78987 -17.77279 58.19454 1.000 27.60946  ? 71  LEU A C     1 
ATOM   547  O  O     . LEU A 1 78  ? -15.37306 -16.88418 58.82934 1.000 30.48996  ? 71  LEU A O     1 
ATOM   548  C  CB    . LEU A 1 78  ? -15.69174 -18.49244 55.96822 1.000 27.63609  ? 71  LEU A CB    1 
ATOM   549  C  CG    . LEU A 1 78  ? -15.93055 -18.18227 54.49074 1.000 28.52720  ? 71  LEU A CG    1 
ATOM   550  C  CD1   . LEU A 1 78  ? -17.12861 -18.96036 53.97253 1.000 32.26560  ? 71  LEU A CD1   1 
ATOM   551  C  CD2   . LEU A 1 78  ? -16.14761 -16.68572 54.30186 1.000 33.00383  ? 71  LEU A CD2   1 
ATOM   552  N  N     . ARG A 1 79  ? -14.28552 -18.85606 58.78802 1.000 28.07587  ? 72  ARG A N     1 
ATOM   553  C  CA    . ARG A 1 79  ? -14.39484 -19.02526 60.23389 1.000 30.05833  ? 72  ARG A CA    1 
ATOM   554  C  C     . ARG A 1 79  ? -13.54769 -17.99393 60.97649 1.000 32.19795  ? 72  ARG A C     1 
ATOM   555  O  O     . ARG A 1 79  ? -14.02514 -17.36758 61.92695 1.000 32.84204  ? 72  ARG A O     1 
ATOM   556  C  CB    . ARG A 1 79  ? -14.00369 -20.45245 60.61771 1.000 34.32242  ? 72  ARG A CB    1 
ATOM   557  C  CG    . ARG A 1 79  ? -14.99750 -21.50269 60.11699 1.000 35.22737  ? 72  ARG A CG    1 
ATOM   558  C  CD    . ARG A 1 79  ? -14.76825 -22.90059 60.71596 1.000 35.82832  ? 72  ARG A CD    1 
ATOM   559  N  NE    . ARG A 1 79  ? -13.53111 -23.52111 60.25187 1.000 38.94164  ? 72  ARG A NE    1 
ATOM   560  C  CZ    . ARG A 1 79  ? -13.43958 -24.32316 59.19842 1.000 40.87039  ? 72  ARG A CZ    1 
ATOM   561  N  NH1   . ARG A 1 79  ? -14.49709 -24.61866 58.45861 1.000 34.37620  ? 72  ARG A NH1   1 
ATOM   562  N  NH2   . ARG A 1 79  ? -12.25566 -24.83852 58.87574 1.000 35.35103  ? 72  ARG A NH2   1 
ATOM   563  N  N     . TRP A 1 80  ? -12.29896 -17.78264 60.54948 1.000 27.80268  ? 73  TRP A N     1 
ATOM   564  C  CA    . TRP A 1 80  ? -11.46502 -16.76415 61.18632 1.000 33.58864  ? 73  TRP A CA    1 
ATOM   565  C  C     . TRP A 1 80  ? -12.09589 -15.38086 61.05479 1.000 30.98852  ? 73  TRP A C     1 
ATOM   566  O  O     . TRP A 1 80  ? -12.22324 -14.64136 62.03974 1.000 30.87723  ? 73  TRP A O     1 
ATOM   567  C  CB    . TRP A 1 80  ? -10.05317 -16.76558 60.58283 1.000 32.43655  ? 73  TRP A CB    1 
ATOM   568  C  CG    . TRP A 1 80  ? -9.30285  -15.49680 60.90439 1.000 30.11505  ? 73  TRP A CG    1 
ATOM   569  C  CD1   . TRP A 1 80  ? -8.64426  -15.21640 62.06683 1.000 31.16382  ? 73  TRP A CD1   1 
ATOM   570  C  CD2   . TRP A 1 80  ? -9.14241  -14.34649 60.06692 1.000 28.30758  ? 73  TRP A CD2   1 
ATOM   571  N  NE1   . TRP A 1 80  ? -8.10088  -13.95988 62.01440 1.000 32.31217  ? 73  TRP A NE1   1 
ATOM   572  C  CE2   . TRP A 1 80  ? -8.38609  -13.40443 60.79363 1.000 31.56292  ? 73  TRP A CE2   1 
ATOM   573  C  CE3   . TRP A 1 80  ? -9.57546  -14.01526 58.77783 1.000 29.24881  ? 73  TRP A CE3   1 
ATOM   574  C  CZ2   . TRP A 1 80  ? -8.04388  -12.16037 60.27326 1.000 32.28824  ? 73  TRP A CZ2   1 
ATOM   575  C  CZ3   . TRP A 1 80  ? -9.22378  -12.78663 58.25432 1.000 29.45320  ? 73  TRP A CZ3   1 
ATOM   576  C  CH2   . TRP A 1 80  ? -8.46982  -11.87023 59.00411 1.000 33.28308  ? 73  TRP A CH2   1 
ATOM   577  N  N     . PHE A 1 81  ? -12.52571 -15.03019 59.84417 1.000 27.13267  ? 74  PHE A N     1 
ATOM   578  C  CA    . PHE A 1 81  ? -13.06086 -13.69720 59.57883 1.000 29.57290  ? 74  PHE A CA    1 
ATOM   579  C  C     . PHE A 1 81  ? -14.28275 -13.41201 60.43990 1.000 33.36515  ? 74  PHE A C     1 
ATOM   580  O  O     . PHE A 1 81  ? -14.47430 -12.28501 60.92071 1.000 29.75667  ? 74  PHE A O     1 
ATOM   581  C  CB    . PHE A 1 81  ? -13.41106 -13.57780 58.09351 1.000 27.17236  ? 74  PHE A CB    1 
ATOM   582  C  CG    . PHE A 1 81  ? -13.63473 -12.16722 57.62516 1.000 29.20204  ? 74  PHE A CG    1 
ATOM   583  C  CD1   . PHE A 1 81  ? -12.79784 -11.14104 58.04135 1.000 32.14410  ? 74  PHE A CD1   1 
ATOM   584  C  CD2   . PHE A 1 81  ? -14.67795 -11.86746 56.76314 1.000 29.75085  ? 74  PHE A CD2   1 
ATOM   585  C  CE1   . PHE A 1 81  ? -12.99687 -9.84286  57.59930 1.000 29.72900  ? 74  PHE A CE1   1 
ATOM   586  C  CE2   . PHE A 1 81  ? -14.88385 -10.56477 56.32265 1.000 32.88536  ? 74  PHE A CE2   1 
ATOM   587  C  CZ    . PHE A 1 81  ? -14.03845 -9.55533  56.73587 1.000 29.39977  ? 74  PHE A CZ    1 
ATOM   588  N  N     . HIS A 1 82  ? -15.11803 -14.42590 60.65544 1.000 27.56445  ? 75  HIS A N     1 
ATOM   589  C  CA    . HIS A 1 82  ? -16.32335 -14.21460 61.43941 1.000 34.75698  ? 75  HIS A CA    1 
ATOM   590  C  C     . HIS A 1 82  ? -15.97771 -13.85921 62.88267 1.000 37.72213  ? 75  HIS A C     1 
ATOM   591  O  O     . HIS A 1 82  ? -16.61287 -12.98364 63.47955 1.000 35.01967  ? 75  HIS A O     1 
ATOM   592  C  CB    . HIS A 1 82  ? -17.21845 -15.45430 61.37152 1.000 34.66667  ? 75  HIS A CB    1 
ATOM   593  C  CG    . HIS A 1 82  ? -18.41507 -15.37420 62.26354 1.000 38.70639  ? 75  HIS A CG    1 
ATOM   594  N  ND1   . HIS A 1 82  ? -18.37239 -15.69666 63.60304 1.000 49.63115  ? 75  HIS A ND1   1 
ATOM   595  C  CD2   . HIS A 1 82  ? -19.68387 -14.97244 62.01279 1.000 41.53663  ? 75  HIS A CD2   1 
ATOM   596  C  CE1   . HIS A 1 82  ? -19.56818 -15.51781 64.13548 1.000 48.26826  ? 75  HIS A CE1   1 
ATOM   597  N  NE2   . HIS A 1 82  ? -20.38127 -15.07492 63.19276 1.000 51.72150  ? 75  HIS A NE2   1 
ATOM   598  N  N     . LYS A 1 83  ? -14.96540 -14.51889 63.45824 1.000 38.13382  ? 76  LYS A N     1 
ATOM   599  C  CA    . LYS A 1 83  ? -14.55977 -14.17631 64.81986 1.000 34.97958  ? 76  LYS A CA    1 
ATOM   600  C  C     . LYS A 1 83  ? -13.79908 -12.85605 64.85625 1.000 36.14121  ? 76  LYS A C     1 
ATOM   601  O  O     . LYS A 1 83  ? -13.94582 -12.07721 65.80496 1.000 38.55752  ? 76  LYS A O     1 
ATOM   602  C  CB    . LYS A 1 83  ? -13.70464 -15.27699 65.45667 1.000 42.05836  ? 76  LYS A CB    1 
ATOM   603  C  CG    . LYS A 1 83  ? -13.89677 -16.73324 65.00758 1.000 53.33917  ? 76  LYS A CG    1 
ATOM   604  C  CD    . LYS A 1 83  ? -15.36546 -17.20580 64.97391 1.000 62.89603  ? 76  LYS A CD    1 
ATOM   605  C  CE    . LYS A 1 83  ? -15.51343 -18.46516 64.08203 1.000 52.76486  ? 76  LYS A CE    1 
ATOM   606  N  NZ    . LYS A 1 83  ? -16.79624 -18.61831 63.32017 1.000 47.01657  ? 76  LYS A NZ    1 
ATOM   607  N  N     . TRP A 1 84  ? -12.96586 -12.60374 63.84324 1.000 31.02973  ? 77  TRP A N     1 
ATOM   608  C  CA    . TRP A 1 84  ? -12.23548 -11.34249 63.75178 1.000 28.25652  ? 77  TRP A CA    1 
ATOM   609  C  C     . TRP A 1 84  ? -13.19055 -10.15477 63.72628 1.000 35.13812  ? 77  TRP A C     1 
ATOM   610  O  O     . TRP A 1 84  ? -12.97306 -9.15371  64.41894 1.000 34.12459  ? 77  TRP A O     1 
ATOM   611  C  CB    . TRP A 1 84  ? -11.33733 -11.36413 62.50349 1.000 29.97808  ? 77  TRP A CB    1 
ATOM   612  C  CG    . TRP A 1 84  ? -10.50320 -10.12731 62.36213 1.000 34.70325  ? 77  TRP A CG    1 
ATOM   613  C  CD1   . TRP A 1 84  ? -9.24646  -9.91527  62.85857 1.000 37.93070  ? 77  TRP A CD1   1 
ATOM   614  C  CD2   . TRP A 1 84  ? -10.87862 -8.92162  61.69131 1.000 30.25225  ? 77  TRP A CD2   1 
ATOM   615  N  NE1   . TRP A 1 84  ? -8.81694  -8.64714  62.53251 1.000 35.63322  ? 77  TRP A NE1   1 
ATOM   616  C  CE2   . TRP A 1 84  ? -9.80342  -8.01661  61.81942 1.000 33.67842  ? 77  TRP A CE2   1 
ATOM   617  C  CE3   . TRP A 1 84  ? -12.02279 -8.51709  60.99496 1.000 30.58862  ? 77  TRP A CE3   1 
ATOM   618  C  CZ2   . TRP A 1 84  ? -9.84148  -6.73141  61.27756 1.000 35.42130  ? 77  TRP A CZ2   1 
ATOM   619  C  CZ3   . TRP A 1 84  ? -12.06129 -7.24055  60.46453 1.000 32.97166  ? 77  TRP A CZ3   1 
ATOM   620  C  CH2   . TRP A 1 84  ? -10.97621 -6.36318  60.60968 1.000 39.40437  ? 77  TRP A CH2   1 
ATOM   621  N  N     . ARG A 1 85  ? -14.26808 -10.25588 62.94895 1.000 31.57183  ? 78  ARG A N     1 
ATOM   622  C  CA    . ARG A 1 85  ? -15.21887 -9.15448  62.86169 1.000 37.44548  ? 78  ARG A CA    1 
ATOM   623  C  C     . ARG A 1 85  ? -15.90096 -8.88573  64.19234 1.000 37.27589  ? 78  ARG A C     1 
ATOM   624  O  O     . ARG A 1 85  ? -16.26754 -7.73931  64.47911 1.000 36.83576  ? 78  ARG A O     1 
ATOM   625  C  CB    . ARG A 1 85  ? -16.25198 -9.45614  61.78514 1.000 32.07561  ? 78  ARG A CB    1 
ATOM   626  C  CG    . ARG A 1 85  ? -15.69435 -9.29555  60.39018 1.000 35.43275  ? 78  ARG A CG    1 
ATOM   627  C  CD    . ARG A 1 85  ? -16.68379 -9.79472  59.39099 1.000 36.76710  ? 78  ARG A CD    1 
ATOM   628  N  NE    . ARG A 1 85  ? -17.68364 -8.79007  59.06245 1.000 42.74286  ? 78  ARG A NE    1 
ATOM   629  C  CZ    . ARG A 1 85  ? -18.70713 -9.01705  58.25304 1.000 47.98666  ? 78  ARG A CZ    1 
ATOM   630  N  NH1   . ARG A 1 85  ? -18.90558 -10.20922 57.71247 1.000 42.71453  ? 78  ARG A NH1   1 
ATOM   631  N  NH2   . ARG A 1 85  ? -19.55497 -8.02906  57.98561 1.000 43.68265  ? 78  ARG A NH2   1 
ATOM   632  N  N     . GLN A 1 86  ? -16.08621 -9.91627  65.02247 1.000 37.33005  ? 79  GLN A N     1 
ATOM   633  C  CA    . GLN A 1 86  ? -16.67306 -9.66286  66.33355 1.000 41.51316  ? 79  GLN A CA    1 
ATOM   634  C  C     . GLN A 1 86  ? -15.75556 -8.82457  67.21025 1.000 40.21569  ? 79  GLN A C     1 
ATOM   635  O  O     . GLN A 1 86  ? -16.23300 -8.11004  68.09641 1.000 46.27499  ? 79  GLN A O     1 
ATOM   636  C  CB    . GLN A 1 86  ? -16.99058 -10.97288 67.04842 1.000 38.91286  ? 79  GLN A CB    1 
ATOM   637  C  CG    . GLN A 1 86  ? -17.85263 -11.92861 66.26641 1.000 46.43427  ? 79  GLN A CG    1 
ATOM   638  C  CD    . GLN A 1 86  ? -18.11441 -13.20161 67.04467 1.000 61.49566  ? 79  GLN A CD    1 
ATOM   639  O  OE1   . GLN A 1 86  ? -17.22583 -13.72309 67.72390 1.000 58.57050  ? 79  GLN A OE1   1 
ATOM   640  N  NE2   . GLN A 1 86  ? -19.34338 -13.69708 66.97056 1.000 67.14787  ? 79  GLN A NE2   1 
ATOM   641  N  N     . LEU A 1 87  ? -14.44872 -8.92069  67.00508 1.000 36.52378  ? 80  LEU A N     1 
ATOM   642  C  CA    . LEU A 1 87  ? -13.48697 -8.25215  67.86633 1.000 37.34842  ? 80  LEU A CA    1 
ATOM   643  C  C     . LEU A 1 87  ? -13.10142 -6.87247  67.36004 1.000 36.74717  ? 80  LEU A C     1 
ATOM   644  O  O     . LEU A 1 87  ? -12.22992 -6.23780  67.95908 1.000 39.64253  ? 80  LEU A O     1 
ATOM   645  C  CB    . LEU A 1 87  ? -12.22826 -9.10974  68.00822 1.000 34.64258  ? 80  LEU A CB    1 
ATOM   646  C  CG    . LEU A 1 87  ? -12.46437 -10.50109 68.59945 1.000 39.75983  ? 80  LEU A CG    1 
ATOM   647  C  CD1   . LEU A 1 87  ? -11.20542 -11.35632 68.48945 1.000 45.24991  ? 80  LEU A CD1   1 
ATOM   648  C  CD2   . LEU A 1 87  ? -12.92060 -10.37730 70.03702 1.000 36.48916  ? 80  LEU A CD2   1 
ATOM   649  N  N     . HIS A 1 88  ? -13.71664 -6.39978  66.27882 1.000 31.48236  ? 81  HIS A N     1 
ATOM   650  C  CA    . HIS A 1 88  ? -13.35253 -5.12592  65.67536 1.000 34.91546  ? 81  HIS A CA    1 
ATOM   651  C  C     . HIS A 1 88  ? -14.60857 -4.31990  65.37334 1.000 39.86770  ? 81  HIS A C     1 
ATOM   652  O  O     . HIS A 1 88  ? -15.68835 -4.87720  65.17332 1.000 33.71510  ? 81  HIS A O     1 
ATOM   653  C  CB    . HIS A 1 88  ? -12.49585 -5.36644  64.41029 1.000 33.25082  ? 81  HIS A CB    1 
ATOM   654  C  CG    . HIS A 1 88  ? -11.15419 -5.95034  64.72549 1.000 41.36962  ? 81  HIS A CG    1 
ATOM   655  N  ND1   . HIS A 1 88  ? -10.95738 -7.30378  64.90764 1.000 39.90791  ? 81  HIS A ND1   1 
ATOM   656  C  CD2   . HIS A 1 88  ? -9.96033  -5.36039  64.97433 1.000 42.06149  ? 81  HIS A CD2   1 
ATOM   657  C  CE1   . HIS A 1 88  ? -9.69270  -7.52457  65.22001 1.000 36.84419  ? 81  HIS A CE1   1 
ATOM   658  N  NE2   . HIS A 1 88  ? -9.06484  -6.36201  65.26352 1.000 44.80211  ? 81  HIS A NE2   1 
ATOM   659  N  N     . HIS A 1 89  ? -14.46861 -2.99408  65.38520 1.000 37.06473  ? 82  HIS A N     1 
ATOM   660  C  CA    . HIS A 1 89  ? -15.61271 -2.11821  65.16612 1.000 35.83841  ? 82  HIS A CA    1 
ATOM   661  C  C     . HIS A 1 89  ? -16.10581 -2.22166  63.72811 1.000 43.58090  ? 82  HIS A C     1 
ATOM   662  O  O     . HIS A 1 89  ? -15.32773 -2.08554  62.77777 1.000 39.10884  ? 82  HIS A O     1 
ATOM   663  C  CB    . HIS A 1 89  ? -15.24546 -0.67507  65.51097 1.000 34.35818  ? 82  HIS A CB    1 
ATOM   664  C  CG    . HIS A 1 89  ? -15.03749 -0.45831  66.97491 1.000 36.00183  ? 82  HIS A CG    1 
ATOM   665  N  ND1   . HIS A 1 89  ? -16.08300 -0.33148  67.86417 1.000 37.66981  ? 82  HIS A ND1   1 
ATOM   666  C  CD2   . HIS A 1 89  ? -13.90622 -0.40570  67.71538 1.000 36.31321  ? 82  HIS A CD2   1 
ATOM   667  C  CE1   . HIS A 1 89  ? -15.60530 -0.18545  69.08698 1.000 38.93636  ? 82  HIS A CE1   1 
ATOM   668  N  NE2   . HIS A 1 89  ? -14.28705 -0.22900  69.02549 1.000 38.14743  ? 82  HIS A NE2   1 
ATOM   669  N  N     . ASP A 1 90  ? -17.40847 -2.46128  63.58336 1.000 42.98802  ? 83  ASP A N     1 
ATOM   670  C  CA    . ASP A 1 90  ? -18.00475 -2.73819  62.28264 1.000 42.99144  ? 83  ASP A CA    1 
ATOM   671  C  C     . ASP A 1 90  ? -17.78526 -1.59276  61.30032 1.000 46.04646  ? 83  ASP A C     1 
ATOM   672  O  O     . ASP A 1 90  ? -17.93833 -0.41938  61.63971 1.000 41.42464  ? 83  ASP A O     1 
ATOM   673  C  CB    . ASP A 1 90  ? -19.50336 -2.99632  62.45104 1.000 44.39115  ? 83  ASP A CB    1 
ATOM   674  C  CG    . ASP A 1 90  ? -20.16295 -3.45279  61.16859 1.000 52.38913  ? 83  ASP A CG    1 
ATOM   675  O  OD1   . ASP A 1 90  ? -19.65354 -4.40654  60.53544 1.000 50.27594  ? 83  ASP A OD1   1 
ATOM   676  O  OD2   . ASP A 1 90  ? -21.18909 -2.85054  60.79086 1.000 56.48334  ? 83  ASP A OD2   1 
ATOM   677  N  N     . GLN A 1 91  ? -17.42569 -1.95056  60.07005 1.000 40.25776  ? 84  GLN A N     1 
ATOM   678  C  CA    . GLN A 1 91  ? -17.29804 -1.01666  58.95889 1.000 34.68695  ? 84  GLN A CA    1 
ATOM   679  C  C     . GLN A 1 91  ? -17.24984 -1.85327  57.69083 1.000 41.00024  ? 84  GLN A C     1 
ATOM   680  O  O     . GLN A 1 91  ? -17.21110 -3.08038  57.74629 1.000 33.67024  ? 84  GLN A O     1 
ATOM   681  C  CB    . GLN A 1 91  ? -16.05516 -0.12972  59.09198 1.000 37.21698  ? 84  GLN A CB    1 
ATOM   682  C  CG    . GLN A 1 91  ? -14.73928 -0.89924  59.15533 1.000 40.23824  ? 84  GLN A CG    1 
ATOM   683  C  CD    . GLN A 1 91  ? -13.52028 0.00969   59.08089 1.000 41.74380  ? 84  GLN A CD    1 
ATOM   684  O  OE1   . GLN A 1 91  ? -13.43797 0.88416   58.22628 1.000 44.52457  ? 84  GLN A OE1   1 
ATOM   685  N  NE2   . GLN A 1 91  ? -12.58670 -0.16937  60.01869 1.000 33.80747  ? 84  GLN A NE2   1 
ATOM   686  N  N     . GLU A 1 92  ? -17.25972 -1.18239  56.54839 1.000 43.75343  ? 85  GLU A N     1 
ATOM   687  C  CA    . GLU A 1 92  ? -17.21776 -1.89382  55.28077 1.000 36.86397  ? 85  GLU A CA    1 
ATOM   688  C  C     . GLU A 1 92  ? -15.80404 -2.38941  55.00673 1.000 38.91955  ? 85  GLU A C     1 
ATOM   689  O  O     . GLU A 1 92  ? -14.82415 -1.67539  55.24190 1.000 36.18116  ? 85  GLU A O     1 
ATOM   690  C  CB    . GLU A 1 92  ? -17.71357 -0.98995  54.15308 1.000 41.34007  ? 85  GLU A CB    1 
ATOM   691  C  CG    . GLU A 1 92  ? -19.24005 -0.94780  54.08329 1.000 51.56653  ? 85  GLU A CG    1 
ATOM   692  C  CD    . GLU A 1 92  ? -19.77402 0.01828   53.04033 1.000 64.31247  ? 85  GLU A CD    1 
ATOM   693  O  OE1   . GLU A 1 92  ? -19.79243 1.24291   53.29980 1.000 62.78665  ? 85  GLU A OE1   1 
ATOM   694  O  OE2   . GLU A 1 92  ? -20.18262 -0.44997  51.95749 1.000 68.37217  ? 85  GLU A OE2   1 
ATOM   695  N  N     . TYR A 1 93  ? -15.70381 -3.62635  54.51169 1.000 32.51272  ? 86  TYR A N     1 
ATOM   696  C  CA    . TYR A 1 93  ? -14.42734 -4.28936  54.27969 1.000 32.69858  ? 86  TYR A CA    1 
ATOM   697  C  C     . TYR A 1 93  ? -14.28186 -4.68343  52.82217 1.000 33.60792  ? 86  TYR A C     1 
ATOM   698  O  O     . TYR A 1 93  ? -15.22155 -5.20171  52.21089 1.000 34.86630  ? 86  TYR A O     1 
ATOM   699  C  CB    . TYR A 1 93  ? -14.27688 -5.54646  55.13679 1.000 28.28322  ? 86  TYR A CB    1 
ATOM   700  C  CG    . TYR A 1 93  ? -14.29850 -5.25964  56.62202 1.000 30.97725  ? 86  TYR A CG    1 
ATOM   701  C  CD1   . TYR A 1 93  ? -13.38805 -4.37639  57.18709 1.000 32.86497  ? 86  TYR A CD1   1 
ATOM   702  C  CD2   . TYR A 1 93  ? -15.22610 -5.87201  57.45349 1.000 35.23313  ? 86  TYR A CD2   1 
ATOM   703  C  CE1   . TYR A 1 93  ? -13.40754 -4.10074  58.54855 1.000 29.96945  ? 86  TYR A CE1   1 
ATOM   704  C  CE2   . TYR A 1 93  ? -15.25094 -5.60879  58.82623 1.000 35.03771  ? 86  TYR A CE2   1 
ATOM   705  C  CZ    . TYR A 1 93  ? -14.33738 -4.72376  59.35970 1.000 38.44322  ? 86  TYR A CZ    1 
ATOM   706  O  OH    . TYR A 1 93  ? -14.35291 -4.45288  60.70726 1.000 37.99497  ? 86  TYR A OH    1 
ATOM   707  N  N     . LYS A 1 94  ? -13.09119 -4.44411  52.28026 1.000 28.27345  ? 87  LYS A N     1 
ATOM   708  C  CA    . LYS A 1 94  ? -12.67108 -4.99304  51.00133 1.000 25.93199  ? 87  LYS A CA    1 
ATOM   709  C  C     . LYS A 1 94  ? -11.60173 -6.03766  51.28843 1.000 26.15496  ? 87  LYS A C     1 
ATOM   710  O  O     . LYS A 1 94  ? -10.57680 -5.72597  51.90643 1.000 29.74873  ? 87  LYS A O     1 
ATOM   711  C  CB    . LYS A 1 94  ? -12.14228 -3.89490  50.08328 1.000 30.40353  ? 87  LYS A CB    1 
ATOM   712  C  CG    . LYS A 1 94  ? -13.21366 -2.88025  49.70716 1.000 38.99463  ? 87  LYS A CG    1 
ATOM   713  C  CD    . LYS A 1 94  ? -12.72299 -1.90110  48.66248 1.000 48.27281  ? 87  LYS A CD    1 
ATOM   714  C  CE    . LYS A 1 94  ? -13.83872 -0.95010  48.25278 1.000 59.38237  ? 87  LYS A CE    1 
ATOM   715  N  NZ    . LYS A 1 94  ? -13.67798 -0.50705  46.83782 1.000 70.79268  ? 87  LYS A NZ    1 
ATOM   716  N  N     . VAL A 1 95  ? -11.85984 -7.27595  50.87799 1.000 22.84292  ? 88  VAL A N     1 
ATOM   717  C  CA    . VAL A 1 95  ? -10.97079 -8.40224  51.13135 1.000 21.46828  ? 88  VAL A CA    1 
ATOM   718  C  C     . VAL A 1 95  ? -10.34958 -8.82336  49.80811 1.000 25.05148  ? 88  VAL A C     1 
ATOM   719  O  O     . VAL A 1 95  ? -11.03312 -8.85118  48.78135 1.000 22.34151  ? 88  VAL A O     1 
ATOM   720  C  CB    . VAL A 1 95  ? -11.72260 -9.58336  51.78150 1.000 24.69450  ? 88  VAL A CB    1 
ATOM   721  C  CG1   . VAL A 1 95  ? -10.76884 -10.75020 52.04335 1.000 22.17254  ? 88  VAL A CG1   1 
ATOM   722  C  CG2   . VAL A 1 95  ? -12.41938 -9.13967  53.07269 1.000 29.48630  ? 88  VAL A CG2   1 
ATOM   723  N  N     . THR A 1 96  ? -9.05416  -9.14012  49.83249 1.000 21.70846  ? 89  THR A N     1 
ATOM   724  C  CA    . THR A 1 96  ? -8.33923  -9.67860  48.68001 1.000 21.36217  ? 89  THR A CA    1 
ATOM   725  C  C     . THR A 1 96  ? -7.75403  -11.03779 49.04956 1.000 22.36422  ? 89  THR A C     1 
ATOM   726  O  O     . THR A 1 96  ? -7.19077  -11.19249 50.13895 1.000 23.67289  ? 89  THR A O     1 
ATOM   727  C  CB    . THR A 1 96  ? -7.21584  -8.73594  48.23760 1.000 26.75240  ? 89  THR A CB    1 
ATOM   728  O  OG1   . THR A 1 96  ? -7.75887  -7.44212  47.93751 1.000 27.05793  ? 89  THR A OG1   1 
ATOM   729  C  CG2   . THR A 1 96  ? -6.51843  -9.28927  46.98160 1.000 24.47004  ? 89  THR A CG2   1 
ATOM   730  N  N     . TRP A 1 97  ? -7.90158  -12.01314 48.15138 1.000 21.45517  ? 90  TRP A N     1 
ATOM   731  C  CA    . TRP A 1 97  ? -7.28036  -13.33364 48.26003 1.000 24.65200  ? 90  TRP A CA    1 
ATOM   732  C  C     . TRP A 1 97  ? -6.29493  -13.55153 47.11345 1.000 25.11797  ? 90  TRP A C     1 
ATOM   733  O  O     . TRP A 1 97  ? -6.59686  -13.22479 45.96465 1.000 22.01961  ? 90  TRP A O     1 
ATOM   734  C  CB    . TRP A 1 97  ? -8.31941  -14.45482 48.16264 1.000 19.37312  ? 90  TRP A CB    1 
ATOM   735  C  CG    . TRP A 1 97  ? -9.28470  -14.60692 49.29221 1.000 24.08378  ? 90  TRP A CG    1 
ATOM   736  C  CD1   . TRP A 1 97  ? -9.37049  -13.85162 50.42410 1.000 22.49753  ? 90  TRP A CD1   1 
ATOM   737  C  CD2   . TRP A 1 97  ? -10.32545 -15.59195 49.38175 1.000 23.32337  ? 90  TRP A CD2   1 
ATOM   738  N  NE1   . TRP A 1 97  ? -10.40737 -14.30923 51.21598 1.000 23.42985  ? 90  TRP A NE1   1 
ATOM   739  C  CE2   . TRP A 1 97  ? -11.00830 -15.37252 50.59116 1.000 26.49919  ? 90  TRP A CE2   1 
ATOM   740  C  CE3   . TRP A 1 97  ? -10.75695 -16.62602 48.53812 1.000 21.98098  ? 90  TRP A CE3   1 
ATOM   741  C  CZ2   . TRP A 1 97  ? -12.08782 -16.16199 50.99308 1.000 26.24111  ? 90  TRP A CZ2   1 
ATOM   742  C  CZ3   . TRP A 1 97  ? -11.83099 -17.39133 48.92554 1.000 23.08110  ? 90  TRP A CZ3   1 
ATOM   743  C  CH2   . TRP A 1 97  ? -12.48317 -17.16241 50.14846 1.000 25.76858  ? 90  TRP A CH2   1 
ATOM   744  N  N     . TYR A 1 98  ? -5.13688  -14.14477 47.41866 1.000 23.26104  ? 91  TYR A N     1 
ATOM   745  C  CA    . TYR A 1 98  ? -4.26842  -14.77466 46.42508 1.000 22.21758  ? 91  TYR A CA    1 
ATOM   746  C  C     . TYR A 1 98  ? -4.33694  -16.27008 46.73153 1.000 23.21182  ? 91  TYR A C     1 
ATOM   747  O  O     . TYR A 1 98  ? -3.85669  -16.68777 47.78687 1.000 21.87403  ? 91  TYR A O     1 
ATOM   748  C  CB    . TYR A 1 98  ? -2.82122  -14.29398 46.55604 1.000 20.84308  ? 91  TYR A CB    1 
ATOM   749  C  CG    . TYR A 1 98  ? -2.56299  -12.82282 46.26543 1.000 25.17409  ? 91  TYR A CG    1 
ATOM   750  C  CD1   . TYR A 1 98  ? -3.10331  -12.20219 45.15800 1.000 22.45320  ? 91  TYR A CD1   1 
ATOM   751  C  CD2   . TYR A 1 98  ? -1.78245  -12.06387 47.12513 1.000 31.92239  ? 91  TYR A CD2   1 
ATOM   752  C  CE1   . TYR A 1 98  ? -2.86325  -10.83964 44.90491 1.000 24.51496  ? 91  TYR A CE1   1 
ATOM   753  C  CE2   . TYR A 1 98  ? -1.54137  -10.70706 46.88734 1.000 30.23338  ? 91  TYR A CE2   1 
ATOM   754  C  CZ    . TYR A 1 98  ? -2.08329  -10.10644 45.77364 1.000 30.20596  ? 91  TYR A CZ    1 
ATOM   755  O  OH    . TYR A 1 98  ? -1.84829  -8.76260  45.52385 1.000 32.62750  ? 91  TYR A OH    1 
ATOM   756  N  N     . VAL A 1 99  ? -4.95058  -17.07164 45.84843 1.000 19.64904  ? 92  VAL A N     1 
ATOM   757  C  CA    . VAL A 1 99  ? -5.17508  -18.49666 46.11764 1.000 20.08162  ? 92  VAL A CA    1 
ATOM   758  C  C     . VAL A 1 99  ? -4.45225  -19.33767 45.07449 1.000 21.65868  ? 92  VAL A C     1 
ATOM   759  O  O     . VAL A 1 99  ? -4.44013  -18.99299 43.88557 1.000 21.23041  ? 92  VAL A O     1 
ATOM   760  C  CB    . VAL A 1 99  ? -6.67671  -18.86211 46.13194 1.000 26.76312  ? 92  VAL A CB    1 
ATOM   761  C  CG1   . VAL A 1 99  ? -7.36894  -18.22147 47.28562 1.000 34.74300  ? 92  VAL A CG1   1 
ATOM   762  C  CG2   . VAL A 1 99  ? -7.35709  -18.47956 44.82398 1.000 28.82111  ? 92  VAL A CG2   1 
ATOM   763  N  N     . SER A 1 100 ? -3.88080  -20.47703 45.50576 1.000 20.27484  ? 93  SER A N     1 
ATOM   764  C  CA    . SER A 1 100 ? -3.07540  -21.26074 44.56619 1.000 16.92036  ? 93  SER A CA    1 
ATOM   765  C  C     . SER A 1 100 ? -3.94863  -22.02340 43.57457 1.000 24.23688  ? 93  SER A C     1 
ATOM   766  O  O     . SER A 1 100 ? -3.63943  -22.06809 42.37627 1.000 23.32662  ? 93  SER A O     1 
ATOM   767  C  CB    . SER A 1 100 ? -2.15139  -22.21711 45.31109 1.000 21.76918  ? 93  SER A CB    1 
ATOM   768  O  OG    . SER A 1 100 ? -2.86474  -23.01687 46.24386 1.000 21.62429  ? 93  SER A OG    1 
ATOM   769  N  N     . TRP A 1 101 ? -5.03198  -22.63208 44.05405 1.000 22.22790  ? 94  TRP A N     1 
ATOM   770  C  CA    . TRP A 1 101 ? -6.06991  -23.23106 43.22645 1.000 23.47068  ? 94  TRP A CA    1 
ATOM   771  C  C     . TRP A 1 101 ? -7.35194  -22.41445 43.36235 1.000 29.64570  ? 94  TRP A C     1 
ATOM   772  O  O     . TRP A 1 101 ? -7.67939  -21.94440 44.45898 1.000 22.45754  ? 94  TRP A O     1 
ATOM   773  C  CB    . TRP A 1 101 ? -6.36957  -24.67195 43.66406 1.000 17.85851  ? 94  TRP A CB    1 
ATOM   774  C  CG    . TRP A 1 101 ? -5.41226  -25.76908 43.25244 1.000 19.32898  ? 94  TRP A CG    1 
ATOM   775  C  CD1   . TRP A 1 101 ? -4.72483  -26.60803 44.09537 1.000 23.59225  ? 94  TRP A CD1   1 
ATOM   776  C  CD2   . TRP A 1 101 ? -5.10923  -26.20795 41.92013 1.000 20.70865  ? 94  TRP A CD2   1 
ATOM   777  N  NE1   . TRP A 1 101 ? -3.99099  -27.52643 43.36812 1.000 20.71626  ? 94  TRP A NE1   1 
ATOM   778  C  CE2   . TRP A 1 101 ? -4.20933  -27.29925 42.03177 1.000 23.61222  ? 94  TRP A CE2   1 
ATOM   779  C  CE3   . TRP A 1 101 ? -5.50072  -25.78055 40.64119 1.000 22.11502  ? 94  TRP A CE3   1 
ATOM   780  C  CZ2   . TRP A 1 101 ? -3.69353  -27.95992 40.91669 1.000 21.51148  ? 94  TRP A CZ2   1 
ATOM   781  C  CZ3   . TRP A 1 101 ? -4.98502  -26.44149 39.53346 1.000 22.05456  ? 94  TRP A CZ3   1 
ATOM   782  C  CH2   . TRP A 1 101 ? -4.09300  -27.52129 39.68130 1.000 21.52643  ? 94  TRP A CH2   1 
ATOM   783  N  N     . SER A 1 102 ? -8.10119  -22.27961 42.26200 1.000 22.28788  ? 95  SER A N     1 
ATOM   784  C  CA    . SER A 1 102 ? -9.41272  -21.64796 42.33641 1.000 25.85662  ? 95  SER A CA    1 
ATOM   785  C  C     . SER A 1 102 ? -10.37728 -22.52124 43.15163 1.000 23.24142  ? 95  SER A C     1 
ATOM   786  O  O     . SER A 1 102 ? -10.11169 -23.70899 43.39198 1.000 26.71018  ? 95  SER A O     1 
ATOM   787  C  CB    . SER A 1 102 ? -9.96505  -21.39080 40.92899 1.000 21.43217  ? 95  SER A CB    1 
ATOM   788  O  OG    . SER A 1 102 ? -10.08370 -22.59227 40.18268 1.000 21.88220  ? 95  SER A OG    1 
ATOM   789  N  N     . PRO A 1 103 ? -11.50094 -21.95000 43.60305 1.000 25.27800  ? 96  PRO A N     1 
ATOM   790  C  CA    . PRO A 1 103 ? -12.35937 -22.66396 44.55896 1.000 24.08093  ? 96  PRO A CA    1 
ATOM   791  C  C     . PRO A 1 103 ? -13.02643 -23.89217 43.97333 1.000 32.33514  ? 96  PRO A C     1 
ATOM   792  O  O     . PRO A 1 103 ? -13.51381 -23.88773 42.83603 1.000 26.02380  ? 96  PRO A O     1 
ATOM   793  C  CB    . PRO A 1 103 ? -13.40832 -21.61377 44.94524 1.000 27.30351  ? 96  PRO A CB    1 
ATOM   794  C  CG    . PRO A 1 103 ? -12.72106 -20.32131 44.72551 1.000 25.06932  ? 96  PRO A CG    1 
ATOM   795  C  CD    . PRO A 1 103 ? -11.88380 -20.52877 43.50245 1.000 23.35199  ? 96  PRO A CD    1 
ATOM   796  N  N     . CYS A 1 104 ? -13.07502 -24.94516 44.78674 1.000 25.34462  ? 97  CYS A N     1 
ATOM   797  C  CA    . CYS A 1 104 ? -13.88650 -26.09298 44.43493 1.000 29.60543  ? 97  CYS A CA    1 
ATOM   798  C  C     . CYS A 1 104 ? -15.35453 -25.69985 44.51946 1.000 30.21897  ? 97  CYS A C     1 
ATOM   799  O  O     . CYS A 1 104 ? -15.71247 -24.58158 44.91074 1.000 28.75127  ? 97  CYS A O     1 
ATOM   800  C  CB    . CYS A 1 104 ? -13.58731 -27.27912 45.34629 1.000 29.64652  ? 97  CYS A CB    1 
ATOM   801  S  SG    . CYS A 1 104 ? -14.22092 -27.09253 47.04318 1.000 31.32992  ? 97  CYS A SG    1 
ATOM   802  N  N     . THR A 1 105 ? -16.21776 -26.63562 44.13269 1.000 30.24592  ? 98  THR A N     1 
ATOM   803  C  CA    . THR A 1 105 ? -17.64001 -26.32931 44.03466 1.000 32.18286  ? 98  THR A CA    1 
ATOM   804  C  C     . THR A 1 105 ? -18.22652 -26.00157 45.40239 1.000 31.66349  ? 98  THR A C     1 
ATOM   805  O  O     . THR A 1 105 ? -19.07023 -25.10519 45.52874 1.000 34.67702  ? 98  THR A O     1 
ATOM   806  C  CB    . THR A 1 105 ? -18.37282 -27.51575 43.41350 1.000 30.86253  ? 98  THR A CB    1 
ATOM   807  O  OG1   . THR A 1 105 ? -18.25259 -28.63508 44.29561 1.000 31.88623  ? 98  THR A OG1   1 
ATOM   808  C  CG2   . THR A 1 105 ? -17.75292 -27.88470 42.06059 1.000 30.28159  ? 98  THR A CG2   1 
ATOM   809  N  N     . ARG A 1 106 ? -17.79630 -26.73260 46.43629 1.000 32.33988  ? 99  ARG A N     1 
ATOM   810  C  CA    . ARG A 1 106 ? -18.32973 -26.53251 47.78248 1.000 37.04383  ? 99  ARG A CA    1 
ATOM   811  C  C     . ARG A 1 106 ? -17.91480 -25.17928 48.34447 1.000 33.03273  ? 99  ARG A C     1 
ATOM   812  O  O     . ARG A 1 106 ? -18.73865 -24.45031 48.90759 1.000 31.15985  ? 99  ARG A O     1 
ATOM   813  C  CB    . ARG A 1 106 ? -17.85405 -27.65801 48.70102 1.000 31.40791  ? 99  ARG A CB    1 
ATOM   814  C  CG    . ARG A 1 106 ? -18.46431 -29.00685 48.34777 1.000 39.42736  ? 99  ARG A CG    1 
ATOM   815  C  CD    . ARG A 1 106 ? -18.07602 -30.10654 49.33539 1.000 44.88542  ? 99  ARG A CD    1 
ATOM   816  N  NE    . ARG A 1 106 ? -18.79057 -31.36017 49.09501 1.000 40.96692  ? 99  ARG A NE    1 
ATOM   817  C  CZ    . ARG A 1 106 ? -18.72324 -32.08153 47.98123 1.000 54.85065  ? 99  ARG A CZ    1 
ATOM   818  N  NH1   . ARG A 1 106 ? -17.94568 -31.73032 46.96925 1.000 40.32750  ? 99  ARG A NH1   1 
ATOM   819  N  NH2   . ARG A 1 106 ? -19.44398 -33.19745 47.88599 1.000 60.85166  ? 99  ARG A NH2   1 
ATOM   820  N  N     . CYS A 1 107 ? -16.63174 -24.83837 48.21720 1.000 31.28871  ? 100 CYS A N     1 
ATOM   821  C  CA    . CYS A 1 107 ? -16.15665 -23.55527 48.71965 1.000 31.77030  ? 100 CYS A CA    1 
ATOM   822  C  C     . CYS A 1 107 ? -16.77709 -22.40210 47.94868 1.000 31.82223  ? 100 CYS A C     1 
ATOM   823  O  O     . CYS A 1 107 ? -17.16026 -21.38604 48.54093 1.000 32.75368  ? 100 CYS A O     1 
ATOM   824  C  CB    . CYS A 1 107 ? -14.63445 -23.49153 48.63876 1.000 24.17860  ? 100 CYS A CB    1 
ATOM   825  S  SG    . CYS A 1 107 ? -13.82044 -24.47944 49.88504 1.000 26.63569  ? 100 CYS A SG    1 
ATOM   826  N  N     . ALA A 1 108 ? -16.88158 -22.53814 46.62114 1.000 30.23870  ? 101 ALA A N     1 
ATOM   827  C  CA    . ALA A 1 108 ? -17.45728 -21.46091 45.82107 1.000 34.86650  ? 101 ALA A CA    1 
ATOM   828  C  C     . ALA A 1 108 ? -18.87935 -21.15830 46.27097 1.000 35.00491  ? 101 ALA A C     1 
ATOM   829  O  O     . ALA A 1 108 ? -19.27524 -19.99225 46.36669 1.000 33.24266  ? 101 ALA A O     1 
ATOM   830  C  CB    . ALA A 1 108 ? -17.41862 -21.82605 44.33334 1.000 29.88182  ? 101 ALA A CB    1 
ATOM   831  N  N     . ASN A 1 109 ? -19.64933 -22.19973 46.59429 1.000 33.31511  ? 102 ASN A N     1 
ATOM   832  C  CA    . ASN A 1 109 ? -21.02710 -21.99450 47.02901 1.000 35.74960  ? 102 ASN A CA    1 
ATOM   833  C  C     . ASN A 1 109 ? -21.09883 -21.41071 48.43901 1.000 39.52573  ? 102 ASN A C     1 
ATOM   834  O  O     . ASN A 1 109 ? -21.95326 -20.56019 48.71424 1.000 39.56144  ? 102 ASN A O     1 
ATOM   835  C  CB    . ASN A 1 109 ? -21.80367 -23.30970 46.94565 1.000 43.34807  ? 102 ASN A CB    1 
ATOM   836  C  CG    . ASN A 1 109 ? -22.43452 -23.52573 45.57981 1.000 56.81118  ? 102 ASN A CG    1 
ATOM   837  O  OD1   . ASN A 1 109 ? -23.57233 -23.11651 45.34302 1.000 56.36933  ? 102 ASN A OD1   1 
ATOM   838  N  ND2   . ASN A 1 109 ? -21.69833 -24.17140 44.67414 1.000 46.35799  ? 102 ASN A ND2   1 
ATOM   839  N  N     . SER A 1 110 ? -20.22501 -21.85882 49.35100 1.000 36.77519  ? 103 SER A N     1 
ATOM   840  C  CA    . SER A 1 110 ? -20.22541 -21.29850 50.70427 1.000 34.40135  ? 103 SER A CA    1 
ATOM   841  C  C     . SER A 1 110 ? -19.82342 -19.82621 50.69742 1.000 37.49035  ? 103 SER A C     1 
ATOM   842  O  O     . SER A 1 110 ? -20.40867 -19.01268 51.42405 1.000 38.25781  ? 103 SER A O     1 
ATOM   843  C  CB    . SER A 1 110 ? -19.28789 -22.08536 51.62105 1.000 34.99908  ? 103 SER A CB    1 
ATOM   844  O  OG    . SER A 1 110 ? -19.56250 -23.47422 51.58606 1.000 45.68452  ? 103 SER A OG    1 
ATOM   845  N  N     . VAL A 1 111 ? -18.80965 -19.46884 49.90559 1.000 36.55044  ? 104 VAL A N     1 
ATOM   846  C  CA    . VAL A 1 111 ? -18.40375 -18.06698 49.82614 1.000 28.09340  ? 104 VAL A CA    1 
ATOM   847  C  C     . VAL A 1 111 ? -19.49893 -17.24424 49.16481 1.000 42.05768  ? 104 VAL A C     1 
ATOM   848  O  O     . VAL A 1 111 ? -19.83306 -16.14273 49.62191 1.000 39.42072  ? 104 VAL A O     1 
ATOM   849  C  CB    . VAL A 1 111 ? -17.06808 -17.93092 49.07350 1.000 27.42323  ? 104 VAL A CB    1 
ATOM   850  C  CG1   . VAL A 1 111 ? -16.70092 -16.44115 48.89414 1.000 23.59531  ? 104 VAL A CG1   1 
ATOM   851  C  CG2   . VAL A 1 111 ? -15.97159 -18.66902 49.79995 1.000 25.36525  ? 104 VAL A CG2   1 
ATOM   852  N  N     . ALA A 1 112 ? -20.07338 -17.76942 48.07707 1.000 36.95593  ? 105 ALA A N     1 
ATOM   853  C  CA    . ALA A 1 112 ? -21.17305 -17.08929 47.40386 1.000 38.54077  ? 105 ALA A CA    1 
ATOM   854  C  C     . ALA A 1 112 ? -22.31765 -16.80921 48.36844 1.000 40.19112  ? 105 ALA A C     1 
ATOM   855  O  O     . ALA A 1 112 ? -22.87506 -15.70796 48.37482 1.000 41.68420  ? 105 ALA A O     1 
ATOM   856  C  CB    . ALA A 1 112 ? -21.65478 -17.92606 46.21383 1.000 34.23832  ? 105 ALA A CB    1 
ATOM   857  N  N     . THR A 1 113 ? -22.67192 -17.79163 49.20095 1.000 41.50154  ? 106 THR A N     1 
ATOM   858  C  CA    . THR A 1 113 ? -23.73960 -17.59624 50.17854 1.000 37.97613  ? 106 THR A CA    1 
ATOM   859  C  C     . THR A 1 113 ? -23.35304 -16.55144 51.21928 1.000 45.72669  ? 106 THR A C     1 
ATOM   860  O  O     . THR A 1 113 ? -24.18740 -15.73660 51.63388 1.000 47.17979  ? 106 THR A O     1 
ATOM   861  C  CB    . THR A 1 113 ? -24.07405 -18.92751 50.86044 1.000 46.04137  ? 106 THR A CB    1 
ATOM   862  O  OG1   . THR A 1 113 ? -24.54448 -19.86458 49.88312 1.000 49.65155  ? 106 THR A OG1   1 
ATOM   863  C  CG2   . THR A 1 113 ? -25.14475 -18.73870 51.91820 1.000 45.18772  ? 106 THR A CG2   1 
ATOM   864  N  N     . PHE A 1 114 ? -22.09463 -16.56368 51.66034 1.000 41.26656  ? 107 PHE A N     1 
ATOM   865  C  CA    . PHE A 1 114 ? -21.64544 -15.57539 52.63562 1.000 39.20939  ? 107 PHE A CA    1 
ATOM   866  C  C     . PHE A 1 114 ? -21.65416 -14.17105 52.03842 1.000 43.22586  ? 107 PHE A C     1 
ATOM   867  O  O     . PHE A 1 114 ? -22.12886 -13.21980 52.66917 1.000 42.78306  ? 107 PHE A O     1 
ATOM   868  C  CB    . PHE A 1 114 ? -20.24767 -15.94135 53.14153 1.000 39.98448  ? 107 PHE A CB    1 
ATOM   869  C  CG    . PHE A 1 114 ? -19.49687 -14.78232 53.73325 1.000 39.92556  ? 107 PHE A CG    1 
ATOM   870  C  CD1   . PHE A 1 114 ? -19.74754 -14.37307 55.03216 1.000 44.65168  ? 107 PHE A CD1   1 
ATOM   871  C  CD2   . PHE A 1 114 ? -18.54592 -14.10120 52.99169 1.000 34.68867  ? 107 PHE A CD2   1 
ATOM   872  C  CE1   . PHE A 1 114 ? -19.06653 -13.30055 55.58047 1.000 43.51348  ? 107 PHE A CE1   1 
ATOM   873  C  CE2   . PHE A 1 114 ? -17.85943 -13.02889 53.53342 1.000 45.88307  ? 107 PHE A CE2   1 
ATOM   874  C  CZ    . PHE A 1 114 ? -18.12143 -12.63170 54.83941 1.000 37.72665  ? 107 PHE A CZ    1 
ATOM   875  N  N     . LEU A 1 115 ? -21.12710 -14.02294 50.82162 1.000 40.42077  ? 108 LEU A N     1 
ATOM   876  C  CA    . LEU A 1 115 ? -21.10051 -12.71389 50.17527 1.000 39.35922  ? 108 LEU A CA    1 
ATOM   877  C  C     . LEU A 1 115 ? -22.50710 -12.21400 49.87849 1.000 50.47564  ? 108 LEU A C     1 
ATOM   878  O  O     . LEU A 1 115 ? -22.79702 -11.01945 50.03272 1.000 46.77006  ? 108 LEU A O     1 
ATOM   879  C  CB    . LEU A 1 115 ? -20.29462 -12.78749 48.88017 1.000 33.72445  ? 108 LEU A CB    1 
ATOM   880  C  CG    . LEU A 1 115 ? -18.77853 -12.86731 48.99642 1.000 35.29412  ? 108 LEU A CG    1 
ATOM   881  C  CD1   . LEU A 1 115 ? -18.15355 -12.93179 47.60025 1.000 31.68559  ? 108 LEU A CD1   1 
ATOM   882  C  CD2   . LEU A 1 115 ? -18.23553 -11.67467 49.79040 1.000 33.29489  ? 108 LEU A CD2   1 
ATOM   883  N  N     . ALA A 1 116 ? -23.39214 -13.11203 49.44053 1.000 45.88459  ? 109 ALA A N     1 
ATOM   884  C  CA    . ALA A 1 116 ? -24.72991 -12.69498 49.03589 1.000 53.99768  ? 109 ALA A CA    1 
ATOM   885  C  C     . ALA A 1 116 ? -25.53929 -12.15644 50.20929 1.000 49.62850  ? 109 ALA A C     1 
ATOM   886  O  O     . ALA A 1 116 ? -26.38816 -11.27839 50.01932 1.000 54.57548  ? 109 ALA A O     1 
ATOM   887  C  CB    . ALA A 1 116 ? -25.46634 -13.85991 48.37284 1.000 52.09789  ? 109 ALA A CB    1 
ATOM   888  N  N     . LYS A 1 117 ? -25.29558 -12.65422 51.42006 1.000 46.44925  ? 110 LYS A N     1 
ATOM   889  C  CA    . LYS A 1 117 ? -26.06066 -12.23794 52.58938 1.000 57.88638  ? 110 LYS A CA    1 
ATOM   890  C  C     . LYS A 1 117 ? -25.33156 -11.21268 53.45037 1.000 50.74175  ? 110 LYS A C     1 
ATOM   891  O  O     . LYS A 1 117 ? -25.74806 -10.97032 54.58553 1.000 58.54286  ? 110 LYS A O     1 
ATOM   892  C  CB    . LYS A 1 117 ? -26.44234 -13.45138 53.44636 1.000 58.11604  ? 110 LYS A CB    1 
ATOM   893  C  CG    . LYS A 1 117 ? -27.46420 -14.38743 52.80187 1.000 61.92527  ? 110 LYS A CG    1 
ATOM   894  C  CD    . LYS A 1 117 ? -27.19018 -15.85787 53.11625 1.000 62.85754  ? 110 LYS A CD    1 
ATOM   895  C  CE    . LYS A 1 117 ? -26.35573 -16.02458 54.38432 1.000 70.19259  ? 110 LYS A CE    1 
ATOM   896  N  NZ    . LYS A 1 117 ? -26.56667 -17.35611 55.02908 1.000 71.54381  ? 110 LYS A NZ    1 
ATOM   897  N  N     . ASP A 1 118 ? -24.25714 -10.60805 52.94804 1.000 52.41524  ? 111 ASP A N     1 
ATOM   898  C  CA    . ASP A 1 118 ? -23.51120 -9.60100  53.70132 1.000 52.82994  ? 111 ASP A CA    1 
ATOM   899  C  C     . ASP A 1 118 ? -23.10510 -8.47249  52.76343 1.000 44.99371  ? 111 ASP A C     1 
ATOM   900  O  O     . ASP A 1 118 ? -22.07109 -8.56040  52.08161 1.000 44.75252  ? 111 ASP A O     1 
ATOM   901  C  CB    . ASP A 1 118 ? -22.28906 -10.20627 54.38392 1.000 47.36492  ? 111 ASP A CB    1 
ATOM   902  C  CG    . ASP A 1 118 ? -21.65744 -9.26079  55.38040 1.000 52.18308  ? 111 ASP A CG    1 
ATOM   903  O  OD1   . ASP A 1 118 ? -21.95414 -8.04662  55.33016 1.000 48.20941  ? 111 ASP A OD1   1 
ATOM   904  O  OD2   . ASP A 1 118 ? -20.86468 -9.73288  56.21828 1.000 49.90500  ? 111 ASP A OD2   1 
ATOM   905  N  N     . PRO A 1 119 ? -23.87278 -7.38197  52.72452 1.000 45.74470  ? 112 PRO A N     1 
ATOM   906  C  CA    . PRO A 1 119 ? -23.54462 -6.28376  51.80893 1.000 48.33544  ? 112 PRO A CA    1 
ATOM   907  C  C     . PRO A 1 119 ? -22.33989 -5.45369  52.23016 1.000 47.92114  ? 112 PRO A C     1 
ATOM   908  O  O     . PRO A 1 119 ? -21.88372 -4.62296  51.43684 1.000 45.25853  ? 112 PRO A O     1 
ATOM   909  C  CB    . PRO A 1 119 ? -24.82833 -5.44534  51.82294 1.000 51.97984  ? 112 PRO A CB    1 
ATOM   910  C  CG    . PRO A 1 119 ? -25.32506 -5.61887  53.21145 1.000 51.44901  ? 112 PRO A CG    1 
ATOM   911  C  CD    . PRO A 1 119 ? -25.07325 -7.08202  53.52509 1.000 52.74484  ? 112 PRO A CD    1 
ATOM   912  N  N     . LYS A 1 120 ? -21.80072 -5.65125  53.43109 1.000 42.03864  ? 113 LYS A N     1 
ATOM   913  C  CA    . LYS A 1 120 ? -20.67856 -4.83787  53.87677 1.000 42.69832  ? 113 LYS A CA    1 
ATOM   914  C  C     . LYS A 1 120 ? -19.32174 -5.39983  53.46800 1.000 39.51608  ? 113 LYS A C     1 
ATOM   915  O  O     . LYS A 1 120 ? -18.30388 -4.73895  53.69973 1.000 40.99751  ? 113 LYS A O     1 
ATOM   916  C  CB    . LYS A 1 120 ? -20.72853 -4.66612  55.39956 1.000 46.97987  ? 113 LYS A CB    1 
ATOM   917  C  CG    . LYS A 1 120 ? -21.86338 -3.76567  55.85337 1.000 46.69381  ? 113 LYS A CG    1 
ATOM   918  C  CD    . LYS A 1 120 ? -21.64626 -3.20045  57.25028 1.000 60.39200  ? 113 LYS A CD    1 
ATOM   919  C  CE    . LYS A 1 120 ? -21.69355 -1.67567  57.23194 1.000 62.89637  ? 113 LYS A CE    1 
ATOM   920  N  NZ    . LYS A 1 120 ? -21.21012 -1.06256  58.50147 1.000 61.07131  ? 113 LYS A NZ    1 
ATOM   921  N  N     . VAL A 1 121 ? -19.27496 -6.58040  52.85259 1.000 33.81758  ? 114 VAL A N     1 
ATOM   922  C  CA    . VAL A 1 121 ? -18.01933 -7.22473  52.48270 1.000 34.15663  ? 114 VAL A CA    1 
ATOM   923  C  C     . VAL A 1 121 ? -17.94742 -7.35766  50.96632 1.000 37.22666  ? 114 VAL A C     1 
ATOM   924  O  O     . VAL A 1 121 ? -18.89040 -7.84465  50.33155 1.000 33.15296  ? 114 VAL A O     1 
ATOM   925  C  CB    . VAL A 1 121 ? -17.85829 -8.60156  53.15170 1.000 37.48740  ? 114 VAL A CB    1 
ATOM   926  C  CG1   . VAL A 1 121 ? -16.55047 -9.25528  52.69296 1.000 36.21333  ? 114 VAL A CG1   1 
ATOM   927  C  CG2   . VAL A 1 121 ? -17.90550 -8.46970  54.67826 1.000 34.03630  ? 114 VAL A CG2   1 
ATOM   928  N  N     . THR A 1 122 ? -16.82379 -6.92231  50.40074 1.000 31.93850  ? 115 THR A N     1 
ATOM   929  C  CA    . THR A 1 122 ? -16.49407 -7.05511  48.99038 1.000 32.75760  ? 115 THR A CA    1 
ATOM   930  C  C     . THR A 1 122 ? -15.24246 -7.90992  48.89791 1.000 28.06395  ? 115 THR A C     1 
ATOM   931  O  O     . THR A 1 122 ? -14.31807 -7.75464  49.70280 1.000 28.82022  ? 115 THR A O     1 
ATOM   932  C  CB    . THR A 1 122 ? -16.25774 -5.67234  48.34946 1.000 24.75983  ? 115 THR A CB    1 
ATOM   933  O  OG1   . THR A 1 122 ? -17.52101 -5.02827  48.15933 1.000 46.36542  ? 115 THR A OG1   1 
ATOM   934  C  CG2   . THR A 1 122 ? -15.54477 -5.77759  47.00143 1.000 38.16725  ? 115 THR A CG2   1 
ATOM   935  N  N     . LEU A 1 123 ? -15.21640 -8.82615  47.93899 1.000 25.52863  ? 116 LEU A N     1 
ATOM   936  C  CA    . LEU A 1 123 ? -14.14720 -9.80996  47.87054 1.000 22.83467  ? 116 LEU A CA    1 
ATOM   937  C  C     . LEU A 1 123 ? -13.59387 -9.88278  46.45555 1.000 25.19439  ? 116 LEU A C     1 
ATOM   938  O  O     . LEU A 1 123 ? -14.35671 -9.96443  45.48805 1.000 24.40591  ? 116 LEU A O     1 
ATOM   939  C  CB    . LEU A 1 123 ? -14.65011 -11.18353 48.31684 1.000 25.27346  ? 116 LEU A CB    1 
ATOM   940  C  CG    . LEU A 1 123 ? -13.66027 -12.32755 48.13276 1.000 25.12319  ? 116 LEU A CG    1 
ATOM   941  C  CD1   . LEU A 1 123 ? -12.41683 -12.09601 48.99481 1.000 21.51274  ? 116 LEU A CD1   1 
ATOM   942  C  CD2   . LEU A 1 123 ? -14.33419 -13.67856 48.42702 1.000 26.04298  ? 116 LEU A CD2   1 
ATOM   943  N  N     . THR A 1 124 ? -12.27074 -9.85319  46.34415 1.000 23.12733  ? 117 THR A N     1 
ATOM   944  C  CA    . THR A 1 124 ? -11.56586 -10.08681 45.08974 1.000 22.98206  ? 117 THR A CA    1 
ATOM   945  C  C     . THR A 1 124 ? -10.67835 -11.30916 45.26475 1.000 26.03006  ? 117 THR A C     1 
ATOM   946  O  O     . THR A 1 124 ? -9.92694  -11.38858 46.23931 1.000 21.38238  ? 117 THR A O     1 
ATOM   947  C  CB    . THR A 1 124 ? -10.71747 -8.87081  44.69481 1.000 25.15077  ? 117 THR A CB    1 
ATOM   948  O  OG1   . THR A 1 124 ? -11.56242 -7.71391  44.55383 1.000 26.26330  ? 117 THR A OG1   1 
ATOM   949  C  CG2   . THR A 1 124 ? -9.97388  -9.14391  43.38610 1.000 27.04852  ? 117 THR A CG2   1 
ATOM   950  N  N     . ILE A 1 125 ? -10.76791 -12.25719 44.33100 1.000 21.52139  ? 118 ILE A N     1 
ATOM   951  C  CA    . ILE A 1 125 ? -9.98468  -13.49609 44.37252 1.000 17.91177  ? 118 ILE A CA    1 
ATOM   952  C  C     . ILE A 1 125 ? -9.08228  -13.53286 43.14535 1.000 24.32582  ? 118 ILE A C     1 
ATOM   953  O  O     . ILE A 1 125 ? -9.56809  -13.64026 42.01099 1.000 25.11955  ? 118 ILE A O     1 
ATOM   954  C  CB    . ILE A 1 125 ? -10.88006 -14.73936 44.41265 1.000 22.06311  ? 118 ILE A CB    1 
ATOM   955  C  CG1   . ILE A 1 125 ? -11.88636 -14.62551 45.56074 1.000 21.30160  ? 118 ILE A CG1   1 
ATOM   956  C  CG2   . ILE A 1 125 ? -10.02947 -16.02275 44.51387 1.000 17.11453  ? 118 ILE A CG2   1 
ATOM   957  C  CD1   . ILE A 1 125 ? -12.97610 -15.67294 45.51536 1.000 26.93717  ? 118 ILE A CD1   1 
ATOM   958  N  N     . PHE A 1 126 ? -7.77475  -13.44130 43.36106 1.000 18.48210  ? 119 PHE A N     1 
ATOM   959  C  CA    . PHE A 1 126 ? -6.80268  -13.72614 42.31510 1.000 19.89949  ? 119 PHE A CA    1 
ATOM   960  C  C     . PHE A 1 126 ? -6.38538  -15.19053 42.43338 1.000 19.19819  ? 119 PHE A C     1 
ATOM   961  O  O     . PHE A 1 126 ? -6.00568  -15.63590 43.51781 1.000 22.83677  ? 119 PHE A O     1 
ATOM   962  C  CB    . PHE A 1 126 ? -5.57097  -12.84236 42.46630 1.000 20.80813  ? 119 PHE A CB    1 
ATOM   963  C  CG    . PHE A 1 126 ? -5.80843  -11.39560 42.17281 1.000 22.57302  ? 119 PHE A CG    1 
ATOM   964  C  CD1   . PHE A 1 126 ? -5.78009  -10.91832 40.86332 1.000 21.97253  ? 119 PHE A CD1   1 
ATOM   965  C  CD2   . PHE A 1 126 ? -6.04738  -10.50250 43.20775 1.000 24.59747  ? 119 PHE A CD2   1 
ATOM   966  C  CE1   . PHE A 1 126 ? -5.97823  -9.55414  40.59903 1.000 26.87577  ? 119 PHE A CE1   1 
ATOM   967  C  CE2   . PHE A 1 126 ? -6.25082  -9.14578  42.94733 1.000 28.02694  ? 119 PHE A CE2   1 
ATOM   968  C  CZ    . PHE A 1 126 ? -6.21458  -8.67791  41.64315 1.000 26.30461  ? 119 PHE A CZ    1 
ATOM   969  N  N     . VAL A 1 127 ? -6.42551  -15.93156 41.33143 1.000 21.87100  ? 120 VAL A N     1 
ATOM   970  C  CA    . VAL A 1 127 ? -6.09379  -17.35735 41.36293 1.000 20.42670  ? 120 VAL A CA    1 
ATOM   971  C  C     . VAL A 1 127 ? -4.83713  -17.61266 40.54050 1.000 21.85506  ? 120 VAL A C     1 
ATOM   972  O  O     . VAL A 1 127 ? -4.65859  -17.03901 39.45578 1.000 20.84286  ? 120 VAL A O     1 
ATOM   973  C  CB    . VAL A 1 127 ? -7.27211  -18.22948 40.87961 1.000 28.78211  ? 120 VAL A CB    1 
ATOM   974  C  CG1   . VAL A 1 127 ? -8.57181  -17.81225 41.56096 1.000 25.92450  ? 120 VAL A CG1   1 
ATOM   975  C  CG2   . VAL A 1 127 ? -7.41377  -18.20392 39.38217 1.000 27.23753  ? 120 VAL A CG2   1 
ATOM   976  N  N     . ALA A 1 128 ? -3.95413  -18.46843 41.06612 1.000 18.27708  ? 121 ALA A N     1 
ATOM   977  C  CA    . ALA A 1 128 ? -2.77583  -18.85444 40.29764 1.000 19.81898  ? 121 ALA A CA    1 
ATOM   978  C  C     . ALA A 1 128 ? -3.13244  -19.84881 39.19465 1.000 18.58283  ? 121 ALA A C     1 
ATOM   979  O  O     . ALA A 1 128 ? -2.67197  -19.70232 38.05375 1.000 16.22791  ? 121 ALA A O     1 
ATOM   980  C  CB    . ALA A 1 128 ? -1.71012  -19.44003 41.22464 1.000 18.57391  ? 121 ALA A CB    1 
ATOM   981  N  N     . ARG A 1 129 ? -3.95897  -20.84619 39.51577 1.000 19.96120  ? 122 ARG A N     1 
ATOM   982  C  CA    . ARG A 1 129 ? -4.38779  -21.87501 38.57820 1.000 21.59203  ? 122 ARG A CA    1 
ATOM   983  C  C     . ARG A 1 129 ? -5.89477  -22.06917 38.69213 1.000 23.11025  ? 122 ARG A C     1 
ATOM   984  O  O     . ARG A 1 129 ? -6.47305  -21.86854 39.76503 1.000 24.57034  ? 122 ARG A O     1 
ATOM   985  C  CB    . ARG A 1 129 ? -3.68842  -23.21819 38.86129 1.000 18.31174  ? 122 ARG A CB    1 
ATOM   986  C  CG    . ARG A 1 129 ? -2.19031  -23.24300 38.62456 1.000 19.82389  ? 122 ARG A CG    1 
ATOM   987  C  CD    . ARG A 1 129 ? -1.60355  -24.62541 38.96300 1.000 18.18902  ? 122 ARG A CD    1 
ATOM   988  N  NE    . ARG A 1 129 ? -2.01058  -25.02931 40.30682 1.000 19.46082  ? 122 ARG A NE    1 
ATOM   989  C  CZ    . ARG A 1 129 ? -1.42255  -24.59275 41.41149 1.000 22.14770  ? 122 ARG A CZ    1 
ATOM   990  N  NH1   . ARG A 1 129 ? -0.37096  -23.78838 41.35799 1.000 18.66120  ? 122 ARG A NH1   1 
ATOM   991  N  NH2   . ARG A 1 129 ? -1.91241  -24.95464 42.60136 1.000 18.04513  ? 122 ARG A NH2   1 
ATOM   992  N  N     . LEU A 1 130 ? -6.51878  -22.49782 37.58586 1.000 19.03313  ? 123 LEU A N     1 
ATOM   993  C  CA    . LEU A 1 130 ? -7.93102  -22.87550 37.56806 1.000 19.35509  ? 123 LEU A CA    1 
ATOM   994  C  C     . LEU A 1 130 ? -8.08078  -24.36763 37.86185 1.000 21.24004  ? 123 LEU A C     1 
ATOM   995  O  O     . LEU A 1 130 ? -7.60361  -25.21240 37.09385 1.000 20.79981  ? 123 LEU A O     1 
ATOM   996  C  CB    . LEU A 1 130 ? -8.57867  -22.54257 36.22170 1.000 20.03379  ? 123 LEU A CB    1 
ATOM   997  C  CG    . LEU A 1 130 ? -8.67545  -21.04039 35.93212 1.000 21.82844  ? 123 LEU A CG    1 
ATOM   998  C  CD1   . LEU A 1 130 ? -9.09256  -20.77384 34.47849 1.000 21.57964  ? 123 LEU A CD1   1 
ATOM   999  C  CD2   . LEU A 1 130 ? -9.61414  -20.33353 36.91877 1.000 21.20175  ? 123 LEU A CD2   1 
ATOM   1000 N  N     . TYR A 1 131 ? -8.78822  -24.68285 38.94953 1.000 20.66407  ? 124 TYR A N     1 
ATOM   1001 C  CA    . TYR A 1 131 ? -8.97744  -26.05408 39.41510 1.000 22.38744  ? 124 TYR A CA    1 
ATOM   1002 C  C     . TYR A 1 131 ? -10.14666 -26.68902 38.66325 1.000 23.75550  ? 124 TYR A C     1 
ATOM   1003 O  O     . TYR A 1 131 ? -11.28487 -26.21734 38.77005 1.000 21.82969  ? 124 TYR A O     1 
ATOM   1004 C  CB    . TYR A 1 131 ? -9.22804  -26.04391 40.93238 1.000 21.67969  ? 124 TYR A CB    1 
ATOM   1005 C  CG    . TYR A 1 131 ? -9.14027  -27.38375 41.63155 1.000 25.21523  ? 124 TYR A CG    1 
ATOM   1006 C  CD1   . TYR A 1 131 ? -8.06067  -28.23357 41.42679 1.000 21.67211  ? 124 TYR A CD1   1 
ATOM   1007 C  CD2   . TYR A 1 131 ? -10.14118 -27.79463 42.50729 1.000 28.13803  ? 124 TYR A CD2   1 
ATOM   1008 C  CE1   . TYR A 1 131 ? -7.98678  -29.47050 42.06891 1.000 24.13319  ? 124 TYR A CE1   1 
ATOM   1009 C  CE2   . TYR A 1 131 ? -10.07455 -29.03940 43.16050 1.000 25.71256  ? 124 TYR A CE2   1 
ATOM   1010 C  CZ    . TYR A 1 131 ? -8.99523  -29.85618 42.94414 1.000 27.93589  ? 124 TYR A CZ    1 
ATOM   1011 O  OH    . TYR A 1 131 ? -8.93643  -31.07380 43.58138 1.000 35.25884  ? 124 TYR A OH    1 
ATOM   1012 N  N     . TYR A 1 132 ? -9.86675  -27.74826 37.89467 1.000 21.63129  ? 125 TYR A N     1 
ATOM   1013 C  CA    . TYR A 1 132 ? -10.89932 -28.48920 37.15783 1.000 22.38592  ? 125 TYR A CA    1 
ATOM   1014 C  C     . TYR A 1 132 ? -11.72501 -27.56258 36.25922 1.000 22.59056  ? 125 TYR A C     1 
ATOM   1015 O  O     . TYR A 1 132 ? -12.95284 -27.63751 36.19584 1.000 25.62986  ? 125 TYR A O     1 
ATOM   1016 C  CB    . TYR A 1 132 ? -11.80092 -29.26163 38.11986 1.000 23.26068  ? 125 TYR A CB    1 
ATOM   1017 C  CG    . TYR A 1 132 ? -11.22665 -30.60097 38.55861 1.000 25.49565  ? 125 TYR A CG    1 
ATOM   1018 C  CD1   . TYR A 1 132 ? -10.93168 -31.59178 37.63101 1.000 26.71681  ? 125 TYR A CD1   1 
ATOM   1019 C  CD2   . TYR A 1 132 ? -10.96668 -30.85809 39.90095 1.000 27.05323  ? 125 TYR A CD2   1 
ATOM   1020 C  CE1   . TYR A 1 132 ? -10.39964 -32.80964 38.03173 1.000 24.96015  ? 125 TYR A CE1   1 
ATOM   1021 C  CE2   . TYR A 1 132 ? -10.43410 -32.06536 40.30892 1.000 24.98439  ? 125 TYR A CE2   1 
ATOM   1022 C  CZ    . TYR A 1 132 ? -10.15674 -33.03542 39.37369 1.000 25.83882  ? 125 TYR A CZ    1 
ATOM   1023 O  OH    . TYR A 1 132 ? -9.63238  -34.23279 39.77937 1.000 25.85459  ? 125 TYR A OH    1 
ATOM   1024 N  N     . PHE A 1 133 ? -11.03601 -26.67319 35.55239 1.000 20.75679  ? 126 PHE A N     1 
ATOM   1025 C  CA    . PHE A 1 133 ? -11.74451 -25.66665 34.76486 1.000 22.90130  ? 126 PHE A CA    1 
ATOM   1026 C  C     . PHE A 1 133 ? -12.59558 -26.28468 33.65049 1.000 27.28061  ? 126 PHE A C     1 
ATOM   1027 O  O     . PHE A 1 133 ? -13.53247 -25.63909 33.17494 1.000 27.32212  ? 126 PHE A O     1 
ATOM   1028 C  CB    . PHE A 1 133 ? -10.73513 -24.67309 34.19238 1.000 21.99164  ? 126 PHE A CB    1 
ATOM   1029 C  CG    . PHE A 1 133 ? -9.69930  -25.30792 33.29478 1.000 23.31787  ? 126 PHE A CG    1 
ATOM   1030 C  CD1   . PHE A 1 133 ? -9.99288  -25.59400 31.96946 1.000 29.96857  ? 126 PHE A CD1   1 
ATOM   1031 C  CD2   . PHE A 1 133 ? -8.43152  -25.61430 33.77965 1.000 23.02765  ? 126 PHE A CD2   1 
ATOM   1032 C  CE1   . PHE A 1 133 ? -9.05301  -26.18571 31.13395 1.000 26.98210  ? 126 PHE A CE1   1 
ATOM   1033 C  CE2   . PHE A 1 133 ? -7.48639  -26.20646 32.96119 1.000 24.90194  ? 126 PHE A CE2   1 
ATOM   1034 C  CZ    . PHE A 1 133 ? -7.79348  -26.48608 31.63566 1.000 24.90017  ? 126 PHE A CZ    1 
ATOM   1035 N  N     . TRP A 1 134 ? -12.31620 -27.52534 33.24365 1.000 24.62703  ? 127 TRP A N     1 
ATOM   1036 C  CA    . TRP A 1 134 ? -13.05487 -28.16972 32.15985 1.000 26.57219  ? 127 TRP A CA    1 
ATOM   1037 C  C     . TRP A 1 134 ? -14.29653 -28.90779 32.63317 1.000 27.47057  ? 127 TRP A C     1 
ATOM   1038 O  O     . TRP A 1 134 ? -15.00218 -29.50242 31.80485 1.000 26.54046  ? 127 TRP A O     1 
ATOM   1039 C  CB    . TRP A 1 134 ? -12.14632 -29.14594 31.40414 1.000 28.21389  ? 127 TRP A CB    1 
ATOM   1040 C  CG    . TRP A 1 134 ? -11.62445 -30.28078 32.26346 1.000 24.52154  ? 127 TRP A CG    1 
ATOM   1041 C  CD1   . TRP A 1 134 ? -12.17776 -31.51612 32.42490 1.000 25.44201  ? 127 TRP A CD1   1 
ATOM   1042 C  CD2   . TRP A 1 134 ? -10.44541 -30.25690 33.08081 1.000 22.51634  ? 127 TRP A CD2   1 
ATOM   1043 N  NE1   . TRP A 1 134 ? -11.40673 -32.27001 33.28684 1.000 28.24882  ? 127 TRP A NE1   1 
ATOM   1044 C  CE2   . TRP A 1 134 ? -10.34083 -31.51558 33.70296 1.000 26.19113  ? 127 TRP A CE2   1 
ATOM   1045 C  CE3   . TRP A 1 134 ? -9.47252  -29.28479 33.34965 1.000 26.47404  ? 127 TRP A CE3   1 
ATOM   1046 C  CZ2   . TRP A 1 134 ? -9.29707  -31.83401 34.57310 1.000 25.96821  ? 127 TRP A CZ2   1 
ATOM   1047 C  CZ3   . TRP A 1 134 ? -8.44097  -29.59394 34.21775 1.000 23.14561  ? 127 TRP A CZ3   1 
ATOM   1048 C  CH2   . TRP A 1 134 ? -8.35717  -30.86347 34.81105 1.000 25.01058  ? 127 TRP A CH2   1 
ATOM   1049 N  N     . LYS A 1 135 ? -14.56725 -28.92007 33.94778 1.000 25.21716  ? 128 LYS A N     1 
ATOM   1050 C  CA    . LYS A 1 135 ? -15.68773 -29.70599 34.46190 1.000 27.52225  ? 128 LYS A CA    1 
ATOM   1051 C  C     . LYS A 1 135 ? -16.88082 -28.79997 34.68327 1.000 32.72791  ? 128 LYS A C     1 
ATOM   1052 O  O     . LYS A 1 135 ? -16.75434 -27.78752 35.38619 1.000 28.96053  ? 128 LYS A O     1 
ATOM   1053 C  CB    . LYS A 1 135 ? -15.31999 -30.39806 35.77558 1.000 28.15513  ? 128 LYS A CB    1 
ATOM   1054 C  CG    . LYS A 1 135 ? -14.37216 -31.57349 35.61761 1.000 31.95785  ? 128 LYS A CG    1 
ATOM   1055 C  CD    . LYS A 1 135 ? -14.83848 -32.75606 36.46889 1.000 49.50357  ? 128 LYS A CD    1 
ATOM   1056 C  CE    . LYS A 1 135 ? -13.67704 -33.59207 37.00262 1.000 46.47103  ? 128 LYS A CE    1 
ATOM   1057 N  NZ    . LYS A 1 135 ? -13.91595 -34.08775 38.40136 1.000 46.14676  ? 128 LYS A NZ    1 
ATOM   1058 N  N     . PRO A 1 136 ? -18.03862 -29.13773 34.11824 1.000 34.26281  ? 129 PRO A N     1 
ATOM   1059 C  CA    . PRO A 1 136 ? -19.19125 -28.22665 34.19273 1.000 35.46012  ? 129 PRO A CA    1 
ATOM   1060 C  C     . PRO A 1 136 ? -19.56681 -27.82264 35.60774 1.000 37.85917  ? 129 PRO A C     1 
ATOM   1061 O  O     . PRO A 1 136 ? -19.94621 -26.66605 35.83317 1.000 34.76432  ? 129 PRO A O     1 
ATOM   1062 C  CB    . PRO A 1 136 ? -20.29942 -29.04929 33.52277 1.000 41.45608  ? 129 PRO A CB    1 
ATOM   1063 C  CG    . PRO A 1 136 ? -19.55081 -29.89872 32.52597 1.000 35.73390  ? 129 PRO A CG    1 
ATOM   1064 C  CD    . PRO A 1 136 ? -18.32615 -30.32009 33.28212 1.000 33.95966  ? 129 PRO A CD    1 
ATOM   1065 N  N     . ASP A 1 137 ? -19.46130 -28.74679 36.56567 1.000 32.64481  ? 130 ASP A N     1 
ATOM   1066 C  CA    . ASP A 1 137 ? -19.79489 -28.43713 37.95449 1.000 37.67332  ? 130 ASP A CA    1 
ATOM   1067 C  C     . ASP A 1 137 ? -18.92663 -27.31645 38.50277 1.000 38.22276  ? 130 ASP A C     1 
ATOM   1068 O  O     . ASP A 1 137 ? -19.41060 -26.44789 39.24219 1.000 33.01665  ? 130 ASP A O     1 
ATOM   1069 C  CB    . ASP A 1 137 ? -19.62985 -29.67946 38.81939 1.000 37.46944  ? 130 ASP A CB    1 
ATOM   1070 C  CG    . ASP A 1 137 ? -20.77139 -30.65475 38.66258 1.000 48.71837  ? 130 ASP A CG    1 
ATOM   1071 O  OD1   . ASP A 1 137 ? -21.71336 -30.35447 37.89500 1.000 43.45005  ? 130 ASP A OD1   1 
ATOM   1072 O  OD2   . ASP A 1 137 ? -20.70865 -31.73460 39.28870 1.000 51.96024  ? 130 ASP A OD2   1 
ATOM   1073 N  N     . TYR A 1 138 ? -17.63197 -27.33841 38.17780 1.000 31.23459  ? 131 TYR A N     1 
ATOM   1074 C  CA    . TYR A 1 138 ? -16.73053 -26.30875 38.67454 1.000 28.70169  ? 131 TYR A CA    1 
ATOM   1075 C  C     . TYR A 1 138 ? -16.94583 -24.99973 37.94038 1.000 31.98640  ? 131 TYR A C     1 
ATOM   1076 O  O     . TYR A 1 138 ? -16.84452 -23.92648 38.54187 1.000 29.71447  ? 131 TYR A O     1 
ATOM   1077 C  CB    . TYR A 1 138 ? -15.28206 -26.75295 38.52973 1.000 26.16970  ? 131 TYR A CB    1 
ATOM   1078 C  CG    . TYR A 1 138 ? -14.88708 -27.81355 39.51141 1.000 30.58436  ? 131 TYR A CG    1 
ATOM   1079 C  CD1   . TYR A 1 138 ? -15.32024 -29.12690 39.34514 1.000 30.45155  ? 131 TYR A CD1   1 
ATOM   1080 C  CD2   . TYR A 1 138 ? -14.06409 -27.52150 40.58880 1.000 28.83023  ? 131 TYR A CD2   1 
ATOM   1081 C  CE1   . TYR A 1 138 ? -14.96132 -30.11571 40.23356 1.000 30.68989  ? 131 TYR A CE1   1 
ATOM   1082 C  CE2   . TYR A 1 138 ? -13.69603 -28.51480 41.49019 1.000 33.93521  ? 131 TYR A CE2   1 
ATOM   1083 C  CZ    . TYR A 1 138 ? -14.14684 -29.80667 41.29445 1.000 31.40190  ? 131 TYR A CZ    1 
ATOM   1084 O  OH    . TYR A 1 138 ? -13.79785 -30.80595 42.16783 1.000 30.07504  ? 131 TYR A OH    1 
ATOM   1085 N  N     . GLN A 1 139 ? -17.22516 -25.07080 36.63585 1.000 28.70770  ? 132 GLN A N     1 
ATOM   1086 C  CA    . GLN A 1 139 ? -17.54738 -23.86428 35.88025 1.000 32.41583  ? 132 GLN A CA    1 
ATOM   1087 C  C     . GLN A 1 139 ? -18.77187 -23.16991 36.46396 1.000 33.95597  ? 132 GLN A C     1 
ATOM   1088 O  O     . GLN A 1 139 ? -18.76452 -21.95181 36.68448 1.000 31.18523  ? 132 GLN A O     1 
ATOM   1089 C  CB    . GLN A 1 139 ? -17.77916 -24.21854 34.40913 1.000 32.06715  ? 132 GLN A CB    1 
ATOM   1090 C  CG    . GLN A 1 139 ? -16.59960 -24.91652 33.73773 1.000 36.91855  ? 132 GLN A CG    1 
ATOM   1091 C  CD    . GLN A 1 139 ? -16.95304 -25.48983 32.36549 1.000 44.03928  ? 132 GLN A CD    1 
ATOM   1092 O  OE1   . GLN A 1 139 ? -18.12401 -25.56995 31.99188 1.000 40.29812  ? 132 GLN A OE1   1 
ATOM   1093 N  NE2   . GLN A 1 139 ? -15.93352 -25.90195 31.61780 1.000 35.21090  ? 132 GLN A NE2   1 
ATOM   1094 N  N     . GLN A 1 140 ? -19.83953 -23.93726 36.71294 1.000 38.24833  ? 133 GLN A N     1 
ATOM   1095 C  CA    . GLN A 1 140 ? -21.06524 -23.36531 37.25968 1.000 36.61167  ? 133 GLN A CA    1 
ATOM   1096 C  C     . GLN A 1 140 ? -20.81715 -22.72394 38.61852 1.000 39.89673  ? 133 GLN A C     1 
ATOM   1097 O  O     . GLN A 1 140 ? -21.31757 -21.62901 38.89548 1.000 37.26529  ? 133 GLN A O     1 
ATOM   1098 C  CB    . GLN A 1 140 ? -22.14618 -24.44235 37.36646 1.000 45.46538  ? 133 GLN A CB    1 
ATOM   1099 C  CG    . GLN A 1 140 ? -23.50573 -23.95038 37.86645 1.000 52.34252  ? 133 GLN A CG    1 
ATOM   1100 C  CD    . GLN A 1 140 ? -24.06565 -22.78249 37.05470 1.000 67.29787  ? 133 GLN A CD    1 
ATOM   1101 O  OE1   . GLN A 1 140 ? -23.80701 -22.65159 35.85414 1.000 64.40567  ? 133 GLN A OE1   1 
ATOM   1102 N  NE2   . GLN A 1 140 ? -24.83922 -21.92402 37.71582 1.000 66.06717  ? 133 GLN A NE2   1 
ATOM   1103 N  N     . ALA A 1 141 ? -20.03842 -23.38321 39.47461 1.000 36.35225  ? 134 ALA A N     1 
ATOM   1104 C  CA    . ALA A 1 141 ? -19.82940 -22.86168 40.82038 1.000 34.63431  ? 134 ALA A CA    1 
ATOM   1105 C  C     . ALA A 1 141 ? -19.06392 -21.54368 40.79133 1.000 36.27011  ? 134 ALA A C     1 
ATOM   1106 O  O     . ALA A 1 141 ? -19.35451 -20.63744 41.58209 1.000 34.66833  ? 134 ALA A O     1 
ATOM   1107 C  CB    . ALA A 1 141 ? -19.10458 -23.89871 41.67771 1.000 36.13329  ? 134 ALA A CB    1 
ATOM   1108 N  N     . LEU A 1 142 ? -18.09670 -21.40394 39.87803 1.000 31.99340  ? 135 LEU A N     1 
ATOM   1109 C  CA    . LEU A 1 142 ? -17.40407 -20.12482 39.75003 1.000 27.62712  ? 135 LEU A CA    1 
ATOM   1110 C  C     . LEU A 1 142 ? -18.33760 -19.03101 39.23987 1.000 31.66184  ? 135 LEU A C     1 
ATOM   1111 O  O     . LEU A 1 142 ? -18.19356 -17.86548 39.62600 1.000 26.97584  ? 135 LEU A O     1 
ATOM   1112 C  CB    . LEU A 1 142 ? -16.18977 -20.26539 38.83139 1.000 31.65243  ? 135 LEU A CB    1 
ATOM   1113 C  CG    . LEU A 1 142 ? -15.07977 -21.18856 39.35502 1.000 35.05778  ? 135 LEU A CG    1 
ATOM   1114 C  CD1   . LEU A 1 142 ? -13.81559 -21.06800 38.52370 1.000 31.00605  ? 135 LEU A CD1   1 
ATOM   1115 C  CD2   . LEU A 1 142 ? -14.77902 -20.91890 40.83938 1.000 32.31137  ? 135 LEU A CD2   1 
ATOM   1116 N  N     . ARG A 1 143 ? -19.30343 -19.38003 38.38433 1.000 29.10311  ? 136 ARG A N     1 
ATOM   1117 C  CA    . ARG A 1 143 ? -20.28454 -18.38984 37.95395 1.000 36.13149  ? 136 ARG A CA    1 
ATOM   1118 C  C     . ARG A 1 143 ? -21.18496 -17.97663 39.11335 1.000 35.28808  ? 136 ARG A C     1 
ATOM   1119 O  O     . ARG A 1 143 ? -21.51354 -16.79288 39.25923 1.000 37.65236  ? 136 ARG A O     1 
ATOM   1120 C  CB    . ARG A 1 143 ? -21.11323 -18.93539 36.78781 1.000 36.09984  ? 136 ARG A CB    1 
ATOM   1121 C  CG    . ARG A 1 143 ? -20.35145 -19.00462 35.46373 1.000 33.36093  ? 136 ARG A CG    1 
ATOM   1122 C  CD    . ARG A 1 143 ? -21.28961 -19.25091 34.28027 1.000 34.23541  ? 136 ARG A CD    1 
ATOM   1123 N  NE    . ARG A 1 143 ? -21.87766 -20.58573 34.29557 1.000 36.73104  ? 136 ARG A NE    1 
ATOM   1124 C  CZ    . ARG A 1 143 ? -21.32676 -21.65959 33.74266 1.000 39.70893  ? 136 ARG A CZ    1 
ATOM   1125 N  NH1   . ARG A 1 143 ? -20.15153 -21.60186 33.13970 1.000 29.11943  ? 136 ARG A NH1   1 
ATOM   1126 N  NH2   . ARG A 1 143 ? -21.96391 -22.82380 33.81326 1.000 38.23757  ? 136 ARG A NH2   1 
ATOM   1127 N  N     . ILE A 1 144 ? -21.59952 -18.94047 39.94108 1.000 33.60311  ? 137 ILE A N     1 
ATOM   1128 C  CA    . ILE A 1 144 ? -22.38586 -18.63282 41.13618 1.000 36.57206  ? 137 ILE A CA    1 
ATOM   1129 C  C     . ILE A 1 144 ? -21.62950 -17.66686 42.03469 1.000 33.73839  ? 137 ILE A C     1 
ATOM   1130 O  O     . ILE A 1 144 ? -22.20050 -16.70403 42.56329 1.000 35.70284  ? 137 ILE A O     1 
ATOM   1131 C  CB    . ILE A 1 144 ? -22.74647 -19.93053 41.88860 1.000 39.23545  ? 137 ILE A CB    1 
ATOM   1132 C  CG1   . ILE A 1 144 ? -23.88612 -20.67475 41.18529 1.000 46.78783  ? 137 ILE A CG1   1 
ATOM   1133 C  CG2   . ILE A 1 144 ? -23.10775 -19.64601 43.33348 1.000 39.55681  ? 137 ILE A CG2   1 
ATOM   1134 C  CD1   . ILE A 1 144 ? -23.73953 -22.18995 41.21579 1.000 50.11470  ? 137 ILE A CD1   1 
ATOM   1135 N  N     . LEU A 1 145 ? -20.33611 -17.91791 42.22906 1.000 28.13468  ? 138 LEU A N     1 
ATOM   1136 C  CA    . LEU A 1 145 ? -19.50154 -17.03597 43.03689 1.000 29.45294  ? 138 LEU A CA    1 
ATOM   1137 C  C     . LEU A 1 145 ? -19.40430 -15.64483 42.41776 1.000 30.17783  ? 138 LEU A C     1 
ATOM   1138 O  O     . LEU A 1 145 ? -19.54783 -14.63320 43.11321 1.000 30.07047  ? 138 LEU A O     1 
ATOM   1139 C  CB    . LEU A 1 145 ? -18.11849 -17.66858 43.19399 1.000 33.77577  ? 138 LEU A CB    1 
ATOM   1140 C  CG    . LEU A 1 145 ? -17.05010 -17.03935 44.07941 1.000 36.21484  ? 138 LEU A CG    1 
ATOM   1141 C  CD1   . LEU A 1 145 ? -17.58352 -16.73366 45.46444 1.000 26.46718  ? 138 LEU A CD1   1 
ATOM   1142 C  CD2   . LEU A 1 145 ? -15.84646 -17.97592 44.15163 1.000 28.87087  ? 138 LEU A CD2   1 
ATOM   1143 N  N     . ALA A 1 146 ? -19.16498 -15.57428 41.10301 1.000 26.31515  ? 139 ALA A N     1 
ATOM   1144 C  CA    . ALA A 1 146 ? -19.12660 -14.28082 40.42660 1.000 31.78221  ? 139 ALA A CA    1 
ATOM   1145 C  C     . ALA A 1 146 ? -20.46409 -13.55929 40.53036 1.000 32.49407  ? 139 ALA A C     1 
ATOM   1146 O  O     . ALA A 1 146 ? -20.50711 -12.32935 40.66541 1.000 32.56008  ? 139 ALA A O     1 
ATOM   1147 C  CB    . ALA A 1 146 ? -18.73645 -14.46033 38.95785 1.000 29.88798  ? 139 ALA A CB    1 
ATOM   1148 N  N     . GLU A 1 147 ? -21.56998 -14.30550 40.46005 1.000 30.23693  ? 140 GLU A N     1 
ATOM   1149 C  CA    . GLU A 1 147 ? -22.88763 -13.67885 40.50884 1.000 38.74369  ? 140 GLU A CA    1 
ATOM   1150 C  C     . GLU A 1 147 ? -23.19880 -13.11383 41.88842 1.000 38.58997  ? 140 GLU A C     1 
ATOM   1151 O  O     . GLU A 1 147 ? -23.96851 -12.15340 41.99926 1.000 36.71160  ? 140 GLU A O     1 
ATOM   1152 C  CB    . GLU A 1 147 ? -23.97030 -14.66980 40.08175 1.000 32.80032  ? 140 GLU A CB    1 
ATOM   1153 C  CG    . GLU A 1 147 ? -24.07506 -14.81744 38.55642 1.000 51.84930  ? 140 GLU A CG    1 
ATOM   1154 C  CD    . GLU A 1 147 ? -24.71846 -16.12909 38.11829 1.000 61.45486  ? 140 GLU A CD    1 
ATOM   1155 O  OE1   . GLU A 1 147 ? -24.52443 -16.52582 36.94298 1.000 62.43547  ? 140 GLU A OE1   1 
ATOM   1156 O  OE2   . GLU A 1 147 ? -25.42277 -16.75495 38.94045 1.000 57.77801  ? 140 GLU A OE2   1 
ATOM   1157 N  N     . ALA A 1 148 ? -22.62717 -13.69410 42.94305 1.000 30.98231  ? 141 ALA A N     1 
ATOM   1158 C  CA    . ALA A 1 148 ? -22.73274 -13.12423 44.28086 1.000 29.92299  ? 141 ALA A CA    1 
ATOM   1159 C  C     . ALA A 1 148 ? -21.88507 -11.86869 44.46150 1.000 33.35389  ? 141 ALA A C     1 
ATOM   1160 O  O     . ALA A 1 148 ? -21.91728 -11.28682 45.54963 1.000 34.03585  ? 141 ALA A O     1 
ATOM   1161 C  CB    . ALA A 1 148 ? -22.33644 -14.16897 45.32462 1.000 32.28945  ? 141 ALA A CB    1 
ATOM   1162 N  N     . GLY A 1 149 ? -21.11933 -11.45134 43.44944 1.000 30.19692  ? 142 GLY A N     1 
ATOM   1163 C  CA    . GLY A 1 149 ? -20.34108 -10.22390 43.51049 1.000 28.22038  ? 142 GLY A CA    1 
ATOM   1164 C  C     . GLY A 1 149 ? -18.84537 -10.40625 43.68009 1.000 30.91982  ? 142 GLY A C     1 
ATOM   1165 O  O     . GLY A 1 149 ? -18.12625 -9.40563  43.69671 1.000 28.10716  ? 142 GLY A O     1 
ATOM   1166 N  N     . ALA A 1 150 ? -18.34922 -11.63580 43.82040 1.000 27.13739  ? 147 ALA A N     1 
ATOM   1167 C  CA    . ALA A 1 150 ? -16.91208 -11.85731 43.91634 1.000 25.02696  ? 147 ALA A CA    1 
ATOM   1168 C  C     . ALA A 1 150 ? -16.23428 -11.49275 42.60528 1.000 30.98160  ? 147 ALA A C     1 
ATOM   1169 O  O     . ALA A 1 150 ? -16.71543 -11.84669 41.52734 1.000 31.76220  ? 147 ALA A O     1 
ATOM   1170 C  CB    . ALA A 1 150 ? -16.61915 -13.32045 44.26669 1.000 29.61724  ? 147 ALA A CB    1 
ATOM   1171 N  N     . THR A 1 151 ? -15.11364 -10.78943 42.69244 1.000 25.44924  ? 148 THR A N     1 
ATOM   1172 C  CA    . THR A 1 151 ? -14.34811 -10.40045 41.51274 1.000 27.68614  ? 148 THR A CA    1 
ATOM   1173 C  C     . THR A 1 151 ? -13.23616 -11.42611 41.33633 1.000 32.91843  ? 148 THR A C     1 
ATOM   1174 O  O     . THR A 1 151 ? -12.32345 -11.51845 42.16500 1.000 23.84561  ? 148 THR A O     1 
ATOM   1175 C  CB    . THR A 1 151 ? -13.79082 -8.98458  41.65113 1.000 31.63265  ? 148 THR A CB    1 
ATOM   1176 O  OG1   . THR A 1 151 ? -14.87747 -8.06998  41.81334 1.000 27.38847  ? 148 THR A OG1   1 
ATOM   1177 C  CG2   . THR A 1 151 ? -13.00263 -8.58930  40.40649 1.000 28.59840  ? 148 THR A CG2   1 
ATOM   1178 N  N     . MET A 1 152 ? -13.32142 -12.20674 40.26692 1.000 25.90949  ? 149 MET A N     1 
ATOM   1179 C  CA    . MET A 1 152 ? -12.39477 -13.29983 40.03437 1.000 26.12392  ? 149 MET A CA    1 
ATOM   1180 C  C     . MET A 1 152 ? -11.43886 -12.93704 38.90986 1.000 27.26661  ? 149 MET A C     1 
ATOM   1181 O  O     . MET A 1 152 ? -11.86924 -12.56465 37.81558 1.000 27.67144  ? 149 MET A O     1 
ATOM   1182 C  CB    . MET A 1 152 ? -13.17151 -14.57279 39.71888 1.000 30.94536  ? 149 MET A CB    1 
ATOM   1183 C  CG    . MET A 1 152 ? -13.96994 -15.03794 40.92516 1.000 43.08581  ? 149 MET A CG    1 
ATOM   1184 S  SD    . MET A 1 152 ? -14.28660 -16.78070 40.81947 1.000 55.21366  ? 149 MET A SD    1 
ATOM   1185 C  CE    . MET A 1 152 ? -12.86209 -17.38325 41.71630 1.000 51.27440  ? 149 MET A CE    1 
ATOM   1186 N  N     . LYS A 1 153 ? -10.14425 -13.02704 39.18954 1.000 23.59092  ? 150 LYS A N     1 
ATOM   1187 C  CA    . LYS A 1 153 ? -9.12239  -12.70691 38.20567 1.000 23.51657  ? 150 LYS A CA    1 
ATOM   1188 C  C     . LYS A 1 153 ? -8.02066  -13.75537 38.28173 1.000 26.39104  ? 150 LYS A C     1 
ATOM   1189 O  O     . LYS A 1 153 ? -7.89858  -14.49164 39.26739 1.000 27.53571  ? 150 LYS A O     1 
ATOM   1190 C  CB    . LYS A 1 153 ? -8.52379  -11.31179 38.44264 1.000 24.34502  ? 150 LYS A CB    1 
ATOM   1191 C  CG    . LYS A 1 153 ? -9.55000  -10.17652 38.43839 1.000 30.53814  ? 150 LYS A CG    1 
ATOM   1192 C  CD    . LYS A 1 153 ? -8.93620  -8.86149  38.91788 1.000 43.98621  ? 150 LYS A CD    1 
ATOM   1193 C  CE    . LYS A 1 153 ? -9.65303  -7.64399  38.33121 1.000 50.62398  ? 150 LYS A CE    1 
ATOM   1194 N  NZ    . LYS A 1 153 ? -10.10204 -7.89427  36.93126 1.000 54.67826  ? 150 LYS A NZ    1 
ATOM   1195 N  N     . ILE A 1 154 ? -7.21424  -13.80895 37.22667 1.000 22.31653  ? 151 ILE A N     1 
ATOM   1196 C  CA    . ILE A 1 154 ? -6.01803  -14.63667 37.19160 1.000 22.19873  ? 151 ILE A CA    1 
ATOM   1197 C  C     . ILE A 1 154 ? -4.85035  -13.81635 37.71589 1.000 24.02927  ? 151 ILE A C     1 
ATOM   1198 O  O     . ILE A 1 154 ? -4.67098  -12.65746 37.32771 1.000 24.59825  ? 151 ILE A O     1 
ATOM   1199 C  CB    . ILE A 1 154 ? -5.73599  -15.13309 35.76232 1.000 23.25276  ? 151 ILE A CB    1 
ATOM   1200 C  CG1   . ILE A 1 154 ? -6.93178  -15.91674 35.20737 1.000 23.18232  ? 151 ILE A CG1   1 
ATOM   1201 C  CG2   . ILE A 1 154 ? -4.44896  -15.95562 35.72742 1.000 19.60288  ? 151 ILE A CG2   1 
ATOM   1202 C  CD1   . ILE A 1 154 ? -7.30829  -17.10679 36.05545 1.000 20.57236  ? 151 ILE A CD1   1 
ATOM   1203 N  N     . MET A 1 155 ? -4.04455  -14.42042 38.59377 1.000 23.15368  ? 152 MET A N     1 
ATOM   1204 C  CA    . MET A 1 155 ? -2.81954  -13.77800 39.05864 1.000 22.01159  ? 152 MET A CA    1 
ATOM   1205 C  C     . MET A 1 155 ? -1.87847  -13.55520 37.87689 1.000 24.49902  ? 152 MET A C     1 
ATOM   1206 O  O     . MET A 1 155 ? -1.59783  -14.48376 37.11657 1.000 22.62606  ? 152 MET A O     1 
ATOM   1207 C  CB    . MET A 1 155 ? -2.14317  -14.66510 40.10816 1.000 20.97498  ? 152 MET A CB    1 
ATOM   1208 C  CG    . MET A 1 155 ? -2.78726  -14.64216 41.48772 1.000 21.57431  ? 152 MET A CG    1 
ATOM   1209 S  SD    . MET A 1 155 ? -1.86241  -15.60614 42.71518 1.000 21.68573  ? 152 MET A SD    1 
ATOM   1210 C  CE    . MET A 1 155 ? -0.51082  -14.52554 43.13772 1.000 20.13706  ? 152 MET A CE    1 
ATOM   1211 N  N     . ASN A 1 156 ? -1.38301  -12.32881 37.72630 1.000 22.79960  ? 153 ASN A N     1 
ATOM   1212 C  CA    . ASN A 1 156 ? -0.34505  -12.00896 36.75975 1.000 22.41591  ? 153 ASN A CA    1 
ATOM   1213 C  C     . ASN A 1 156 ? 0.93295   -11.65361 37.50871 1.000 19.05141  ? 153 ASN A C     1 
ATOM   1214 O  O     . ASN A 1 156 ? 0.97571   -11.65860 38.74056 1.000 20.16162  ? 153 ASN A O     1 
ATOM   1215 C  CB    . ASN A 1 156 ? -0.79505  -10.86702 35.83985 1.000 20.55495  ? 153 ASN A CB    1 
ATOM   1216 C  CG    . ASN A 1 156 ? -0.08086  -10.87535 34.48694 1.000 24.28856  ? 153 ASN A CG    1 
ATOM   1217 O  OD1   . ASN A 1 156 ? 0.95558   -11.52059 34.31019 1.000 23.28771  ? 153 ASN A OD1   1 
ATOM   1218 N  ND2   . ASN A 1 156 ? -0.63523  -10.13368 33.53098 1.000 25.04829  ? 153 ASN A ND2   1 
ATOM   1219 N  N     . TYR A 1 157 ? 1.97924   -11.32346 36.74729 1.000 19.40543  ? 154 TYR A N     1 
ATOM   1220 C  CA    . TYR A 1 157 ? 3.27111   -10.95302 37.31935 1.000 21.61733  ? 154 TYR A CA    1 
ATOM   1221 C  C     . TYR A 1 157 ? 3.14515   -10.00196 38.51636 1.000 25.85057  ? 154 TYR A C     1 
ATOM   1222 O  O     . TYR A 1 157 ? 3.74349   -10.23415 39.57606 1.000 19.24483  ? 154 TYR A O     1 
ATOM   1223 C  CB    . TYR A 1 157 ? 4.13961   -10.32842 36.21888 1.000 21.59100  ? 154 TYR A CB    1 
ATOM   1224 C  CG    . TYR A 1 157 ? 5.48630   -9.82152  36.70454 1.000 26.21136  ? 154 TYR A CG    1 
ATOM   1225 C  CD1   . TYR A 1 157 ? 6.60264   -10.64359 36.70406 1.000 23.82386  ? 154 TYR A CD1   1 
ATOM   1226 C  CD2   . TYR A 1 157 ? 5.63082   -8.52511  37.18266 1.000 27.28304  ? 154 TYR A CD2   1 
ATOM   1227 C  CE1   . TYR A 1 157 ? 7.83608   -10.18646 37.14900 1.000 28.64741  ? 154 TYR A CE1   1 
ATOM   1228 C  CE2   . TYR A 1 157 ? 6.85553   -8.05988  37.63973 1.000 26.91162  ? 154 TYR A CE2   1 
ATOM   1229 C  CZ    . TYR A 1 157 ? 7.95171   -8.89260  37.61617 1.000 31.08414  ? 154 TYR A CZ    1 
ATOM   1230 O  OH    . TYR A 1 157 ? 9.16388   -8.42004  38.06866 1.000 37.38265  ? 154 TYR A OH    1 
ATOM   1231 N  N     . ASN A 1 158 ? 2.37304   -8.91372  38.36913 1.000 26.76898  ? 155 ASN A N     1 
ATOM   1232 C  CA    . ASN A 1 158 ? 2.24570   -7.95634  39.47329 1.000 25.63237  ? 155 ASN A CA    1 
ATOM   1233 C  C     . ASN A 1 158 ? 1.69600   -8.62025  40.73416 1.000 24.26392  ? 155 ASN A C     1 
ATOM   1234 O  O     . ASN A 1 158 ? 2.10715   -8.28596  41.85322 1.000 23.82817  ? 155 ASN A O     1 
ATOM   1235 C  CB    . ASN A 1 158 ? 1.35128   -6.77923  39.07118 1.000 22.78534  ? 155 ASN A CB    1 
ATOM   1236 C  CG    . ASN A 1 158 ? 2.02129   -5.84277  38.09299 1.000 32.43988  ? 155 ASN A CG    1 
ATOM   1237 O  OD1   . ASN A 1 158 ? 3.23453   -5.89369  37.89966 1.000 30.72550  ? 155 ASN A OD1   1 
ATOM   1238 N  ND2   . ASN A 1 158 ? 1.23600   -4.98158  37.46853 1.000 31.84152  ? 155 ASN A ND2   1 
ATOM   1239 N  N     . GLU A 1 159 ? 0.77057   -9.56692  40.57983 1.000 23.66145  ? 156 GLU A N     1 
ATOM   1240 C  CA    . GLU A 1 159 ? 0.17593   -10.18412 41.76101 1.000 23.12054  ? 156 GLU A CA    1 
ATOM   1241 C  C     . GLU A 1 159 ? 1.10745   -11.20592 42.39303 1.000 24.72396  ? 156 GLU A C     1 
ATOM   1242 O  O     . GLU A 1 159 ? 1.17523   -11.29503 43.62423 1.000 23.00611  ? 156 GLU A O     1 
ATOM   1243 C  CB    . GLU A 1 159 ? -1.17055  -10.81575 41.41137 1.000 24.56401  ? 156 GLU A CB    1 
ATOM   1244 C  CG    . GLU A 1 159 ? -2.27917  -9.78352  41.19800 1.000 27.29534  ? 156 GLU A CG    1 
ATOM   1245 C  CD    . GLU A 1 159 ? -2.22459  -9.14617  39.82006 1.000 26.64803  ? 156 GLU A CD    1 
ATOM   1246 O  OE1   . GLU A 1 159 ? -1.88415  -9.85447  38.84753 1.000 24.69514  ? 156 GLU A OE1   1 
ATOM   1247 O  OE2   . GLU A 1 159 ? -2.52882  -7.94525  39.71087 1.000 26.30963  ? 156 GLU A OE2   1 
ATOM   1248 N  N     . PHE A 1 160 ? 1.81559   -11.99930 41.57624 1.000 23.33184  ? 157 PHE A N     1 
ATOM   1249 C  CA    . PHE A 1 160 ? 2.85451   -12.86503 42.13041 1.000 23.28948  ? 157 PHE A CA    1 
ATOM   1250 C  C     . PHE A 1 160 ? 3.92476   -12.04399 42.83665 1.000 22.42493  ? 157 PHE A C     1 
ATOM   1251 O  O     . PHE A 1 160 ? 4.37789   -12.40752 43.92546 1.000 22.86680  ? 157 PHE A O     1 
ATOM   1252 C  CB    . PHE A 1 160 ? 3.48579   -13.72324 41.03090 1.000 19.75777  ? 157 PHE A CB    1 
ATOM   1253 C  CG    . PHE A 1 160 ? 2.55132   -14.73862 40.44940 1.000 20.43528  ? 157 PHE A CG    1 
ATOM   1254 C  CD1   . PHE A 1 160 ? 2.10667   -15.80616 41.21202 1.000 20.11662  ? 157 PHE A CD1   1 
ATOM   1255 C  CD2   . PHE A 1 160 ? 2.10290   -14.61823 39.13726 1.000 24.54294  ? 157 PHE A CD2   1 
ATOM   1256 C  CE1   . PHE A 1 160 ? 1.23904   -16.74335 40.67955 1.000 17.73746  ? 157 PHE A CE1   1 
ATOM   1257 C  CE2   . PHE A 1 160 ? 1.24137   -15.55597 38.59874 1.000 20.25063  ? 157 PHE A CE2   1 
ATOM   1258 C  CZ    . PHE A 1 160 ? 0.80129   -16.60800 39.36511 1.000 19.53967  ? 157 PHE A CZ    1 
ATOM   1259 N  N     . GLN A 1 161 ? 4.33958   -10.92456 42.23290 1.000 20.68265  ? 158 GLN A N     1 
ATOM   1260 C  CA    . GLN A 1 161 ? 5.34554   -10.07969 42.87081 1.000 21.72783  ? 158 GLN A CA    1 
ATOM   1261 C  C     . GLN A 1 161 ? 4.82856   -9.51746  44.18607 1.000 23.49586  ? 158 GLN A C     1 
ATOM   1262 O  O     . GLN A 1 161 ? 5.53716   -9.51567  45.19530 1.000 23.74424  ? 158 GLN A O     1 
ATOM   1263 C  CB    . GLN A 1 161 ? 5.74915   -8.93808  41.93451 1.000 24.34125  ? 158 GLN A CB    1 
ATOM   1264 C  CG    . GLN A 1 161 ? 6.72148   -7.94888  42.55659 1.000 26.87735  ? 158 GLN A CG    1 
ATOM   1265 C  CD    . GLN A 1 161 ? 7.11398   -6.87007  41.58422 1.000 34.62914  ? 158 GLN A CD    1 
ATOM   1266 O  OE1   . GLN A 1 161 ? 8.26723   -6.79091  41.15489 1.000 39.10318  ? 158 GLN A OE1   1 
ATOM   1267 N  NE2   . GLN A 1 161 ? 6.13700   -6.06475  41.18067 1.000 29.13235  ? 158 GLN A NE2   1 
ATOM   1268 N  N     . ASP A 1 162 ? 3.59069   -9.02784  44.18686 1.000 23.80144  ? 159 ASP A N     1 
ATOM   1269 C  CA    . ASP A 1 162 ? 3.00269   -8.49593  45.41286 1.000 25.64581  ? 159 ASP A CA    1 
ATOM   1270 C  C     . ASP A 1 162 ? 2.86973   -9.58145  46.47733 1.000 30.16291  ? 159 ASP A C     1 
ATOM   1271 O  O     . ASP A 1 162 ? 3.14776   -9.34524  47.66014 1.000 28.05773  ? 159 ASP A O     1 
ATOM   1272 C  CB    . ASP A 1 162 ? 1.64290   -7.88408  45.09310 1.000 26.97471  ? 159 ASP A CB    1 
ATOM   1273 C  CG    . ASP A 1 162 ? 1.09633   -7.05872  46.22787 1.000 35.74524  ? 159 ASP A CG    1 
ATOM   1274 O  OD1   . ASP A 1 162 ? 1.84047   -6.20334  46.75610 1.000 32.46546  ? 159 ASP A OD1   1 
ATOM   1275 O  OD2   . ASP A 1 162 ? -0.06668  -7.29683  46.61507 1.000 34.18610  ? 159 ASP A OD2   1 
ATOM   1276 N  N     . CYS A 1 163 ? 2.44498   -10.78034 46.07505 1.000 22.34743  ? 160 CYS A N     1 
ATOM   1277 C  CA    . CYS A 1 163 ? 2.32392   -11.88180 47.02617 1.000 19.42399  ? 160 CYS A CA    1 
ATOM   1278 C  C     . CYS A 1 163 ? 3.68106   -12.26541 47.59041 1.000 21.05772  ? 160 CYS A C     1 
ATOM   1279 O  O     . CYS A 1 163 ? 3.81709   -12.53925 48.78929 1.000 26.69514  ? 160 CYS A O     1 
ATOM   1280 C  CB    . CYS A 1 163 ? 1.66857   -13.08464 46.33851 1.000 22.56214  ? 160 CYS A CB    1 
ATOM   1281 S  SG    . CYS A 1 163 ? 1.04962   -14.34287 47.49020 1.000 31.55262  ? 160 CYS A SG    1 
ATOM   1282 N  N     . TRP A 1 164 ? 4.69960   -12.28102 46.73649 1.000 20.91942  ? 161 TRP A N     1 
ATOM   1283 C  CA    . TRP A 1 164 ? 6.06257   -12.52961 47.18636 1.000 21.14545  ? 161 TRP A CA    1 
ATOM   1284 C  C     . TRP A 1 164 ? 6.51006   -11.48525 48.20467 1.000 28.35502  ? 161 TRP A C     1 
ATOM   1285 O  O     . TRP A 1 164 ? 7.07647   -11.82727 49.24911 1.000 25.04386  ? 161 TRP A O     1 
ATOM   1286 C  CB    . TRP A 1 164 ? 6.99497   -12.52665 45.97694 1.000 22.00105  ? 161 TRP A CB    1 
ATOM   1287 C  CG    . TRP A 1 164 ? 8.45310   -12.63301 46.30709 1.000 25.77148  ? 161 TRP A CG    1 
ATOM   1288 C  CD1   . TRP A 1 164 ? 9.32415   -11.59853 46.54588 1.000 27.38862  ? 161 TRP A CD1   1 
ATOM   1289 C  CD2   . TRP A 1 164 ? 9.22558   -13.83586 46.38308 1.000 29.06276  ? 161 TRP A CD2   1 
ATOM   1290 N  NE1   . TRP A 1 164 ? 10.58886  -12.09387 46.78277 1.000 28.14290  ? 161 TRP A NE1   1 
ATOM   1291 C  CE2   . TRP A 1 164 ? 10.55263  -13.46305 46.69095 1.000 28.47429  ? 161 TRP A CE2   1 
ATOM   1292 C  CE3   . TRP A 1 164 ? 8.92244   -15.19989 46.22816 1.000 23.76899  ? 161 TRP A CE3   1 
ATOM   1293 C  CZ2   . TRP A 1 164 ? 11.57410  -14.40265 46.84505 1.000 36.19730  ? 161 TRP A CZ2   1 
ATOM   1294 C  CZ3   . TRP A 1 164 ? 9.93348   -16.12462 46.38710 1.000 25.16979  ? 161 TRP A CZ3   1 
ATOM   1295 C  CH2   . TRP A 1 164 ? 11.24448  -15.72805 46.68823 1.000 26.42730  ? 161 TRP A CH2   1 
ATOM   1296 N  N     . ASN A 1 165 ? 6.27543   -10.19853 47.90752 1.000 25.57361  ? 162 ASN A N     1 
ATOM   1297 C  CA    . ASN A 1 165 ? 6.70985   -9.13084  48.81751 1.000 25.84305  ? 162 ASN A CA    1 
ATOM   1298 C  C     . ASN A 1 165 ? 6.01085   -9.21465  50.17190 1.000 32.72695  ? 162 ASN A C     1 
ATOM   1299 O  O     . ASN A 1 165 ? 6.63049   -8.96188  51.21471 1.000 30.23506  ? 162 ASN A O     1 
ATOM   1300 C  CB    . ASN A 1 165 ? 6.46229   -7.75394  48.18585 1.000 25.12789  ? 162 ASN A CB    1 
ATOM   1301 C  CG    . ASN A 1 165 ? 7.34741   -7.48524  46.98350 1.000 31.16750  ? 162 ASN A CG    1 
ATOM   1302 O  OD1   . ASN A 1 165 ? 8.40407   -8.09996  46.82349 1.000 27.70124  ? 162 ASN A OD1   1 
ATOM   1303 N  ND2   . ASN A 1 165 ? 6.92017   -6.55599  46.12775 1.000 30.90898  ? 162 ASN A ND2   1 
ATOM   1304 N  N     . LYS A 1 166 ? 4.72396   -9.56418  50.17984 1.000 28.44148  ? 163 LYS A N     1 
ATOM   1305 C  CA    . LYS A 1 166 ? 3.91959   -9.48771  51.39555 1.000 26.71901  ? 163 LYS A CA    1 
ATOM   1306 C  C     . LYS A 1 166 ? 3.91752   -10.77318 52.21513 1.000 31.62684  ? 163 LYS A C     1 
ATOM   1307 O  O     . LYS A 1 166 ? 3.92822   -10.71628 53.45330 1.000 29.69182  ? 163 LYS A O     1 
ATOM   1308 C  CB    . LYS A 1 166 ? 2.47490   -9.11865  51.05228 1.000 28.39316  ? 163 LYS A CB    1 
ATOM   1309 C  CG    . LYS A 1 166 ? 2.30868   -7.73389  50.44229 1.000 31.06585  ? 163 LYS A CG    1 
ATOM   1310 C  CD    . LYS A 1 166 ? 0.88507   -7.52669  49.95356 1.000 38.87146  ? 163 LYS A CD    1 
ATOM   1311 C  CE    . LYS A 1 166 ? 0.55362   -6.04600  49.78349 1.000 37.36361  ? 163 LYS A CE    1 
ATOM   1312 N  NZ    . LYS A 1 166 ? -0.66337  -5.89476  48.93812 1.000 33.56441  ? 163 LYS A NZ    1 
ATOM   1313 N  N     . PHE A 1 167 ? 3.87404   -11.93663 51.55897 1.000 20.81909  ? 164 PHE A N     1 
ATOM   1314 C  CA    . PHE A 1 167 ? 3.55144   -13.17182 52.25723 1.000 25.14320  ? 164 PHE A CA    1 
ATOM   1315 C  C     . PHE A 1 167 ? 4.66922   -14.19975 52.26118 1.000 27.88595  ? 164 PHE A C     1 
ATOM   1316 O  O     . PHE A 1 167 ? 4.46088   -15.30897 52.76683 1.000 29.46926  ? 164 PHE A O     1 
ATOM   1317 C  CB    . PHE A 1 167 ? 2.28990   -13.79316 51.64294 1.000 23.56330  ? 164 PHE A CB    1 
ATOM   1318 C  CG    . PHE A 1 167 ? 1.05655   -12.93429 51.80194 1.000 26.12390  ? 164 PHE A CG    1 
ATOM   1319 C  CD1   . PHE A 1 167 ? 0.38353   -12.88279 53.01262 1.000 30.75256  ? 164 PHE A CD1   1 
ATOM   1320 C  CD2   . PHE A 1 167 ? 0.57208   -12.18039 50.74101 1.000 26.04956  ? 164 PHE A CD2   1 
ATOM   1321 C  CE1   . PHE A 1 167 ? -0.74957  -12.09914 53.16559 1.000 23.89419  ? 164 PHE A CE1   1 
ATOM   1322 C  CE2   . PHE A 1 167 ? -0.56351  -11.39162 50.88921 1.000 28.30079  ? 164 PHE A CE2   1 
ATOM   1323 C  CZ    . PHE A 1 167 ? -1.22308  -11.35329 52.09694 1.000 24.67199  ? 164 PHE A CZ    1 
ATOM   1324 N  N     . VAL A 1 168 ? 5.84132   -13.87444 51.72496 1.000 26.64179  ? 165 VAL A N     1 
ATOM   1325 C  CA    . VAL A 1 168 ? 6.91170   -14.84399 51.53436 1.000 31.33182  ? 165 VAL A CA    1 
ATOM   1326 C  C     . VAL A 1 168 ? 8.17712   -14.33252 52.20263 1.000 32.57696  ? 165 VAL A C     1 
ATOM   1327 O  O     . VAL A 1 168 ? 8.48014   -13.13572 52.15288 1.000 29.07806  ? 165 VAL A O     1 
ATOM   1328 C  CB    . VAL A 1 168 ? 7.15489   -15.13089 50.03390 1.000 25.67301  ? 165 VAL A CB    1 
ATOM   1329 C  CG1   . VAL A 1 168 ? 8.30934   -16.09868 49.85025 1.000 23.44476  ? 165 VAL A CG1   1 
ATOM   1330 C  CG2   . VAL A 1 168 ? 5.89546   -15.69489 49.40545 1.000 23.62482  ? 165 VAL A CG2   1 
ATOM   1331 N  N     . ASP A 1 169 ? 8.91303   -15.24858 52.83473 1.000 29.90461  ? 166 ASP A N     1 
ATOM   1332 C  CA    . ASP A 1 169 ? 10.18505  -14.94593 53.49045 1.000 34.09375  ? 166 ASP A CA    1 
ATOM   1333 C  C     . ASP A 1 169 ? 11.27771  -14.82927 52.42345 1.000 39.74449  ? 166 ASP A C     1 
ATOM   1334 O  O     . ASP A 1 169 ? 12.21677  -15.62357 52.34059 1.000 39.84827  ? 166 ASP A O     1 
ATOM   1335 C  CB    . ASP A 1 169 ? 10.49128  -16.02408 54.52301 1.000 34.16067  ? 166 ASP A CB    1 
ATOM   1336 C  CG    . ASP A 1 169 ? 11.62336  -15.64633 55.45797 1.000 47.40313  ? 166 ASP A CG    1 
ATOM   1337 O  OD1   . ASP A 1 169 ? 11.93002  -14.44602 55.58449 1.000 46.53145  ? 166 ASP A OD1   1 
ATOM   1338 O  OD2   . ASP A 1 169 ? 12.20393  -16.56923 56.06928 1.000 48.09578  ? 166 ASP A OD2   1 
ATOM   1339 N  N     . GLY A 1 170 ? 11.12289  -13.80984 51.57674 1.000 32.83435  ? 167 GLY A N     1 
ATOM   1340 C  CA    . GLY A 1 170 ? 12.04790  -13.53894 50.49021 1.000 34.99778  ? 167 GLY A CA    1 
ATOM   1341 C  C     . GLY A 1 170 ? 13.38761  -12.97238 50.91019 1.000 49.99189  ? 167 GLY A C     1 
ATOM   1342 O  O     . GLY A 1 170 ? 14.32889  -12.98676 50.10984 1.000 47.34557  ? 167 GLY A O     1 
ATOM   1343 N  N     . ARG A 1 171 ? 13.48730  -12.46921 52.14089 1.000 49.32697  ? 168 ARG A N     1 
ATOM   1344 C  CA    . ARG A 1 171 ? 14.74904  -11.98288 52.69943 1.000 57.72836  ? 168 ARG A CA    1 
ATOM   1345 C  C     . ARG A 1 171 ? 15.35333  -10.86490 51.84849 1.000 55.25077  ? 168 ARG A C     1 
ATOM   1346 O  O     . ARG A 1 171 ? 16.56372  -10.81418 51.62363 1.000 59.12679  ? 168 ARG A O     1 
ATOM   1347 C  CB    . ARG A 1 171 ? 15.73538  -13.13650 52.87794 1.000 49.01801  ? 168 ARG A CB    1 
ATOM   1348 C  CG    . ARG A 1 171 ? 15.49768  -13.90142 54.15627 1.000 58.12714  ? 168 ARG A CG    1 
ATOM   1349 C  CD    . ARG A 1 171 ? 16.13330  -15.28278 54.12681 1.000 69.00526  ? 168 ARG A CD    1 
ATOM   1350 N  NE    . ARG A 1 171 ? 15.56504  -16.20759 55.10761 1.000 76.69410  ? 168 ARG A NE    1 
ATOM   1351 C  CZ    . ARG A 1 171 ? 15.40147  -15.96822 56.40539 1.000 74.56354  ? 168 ARG A CZ    1 
ATOM   1352 N  NH1   . ARG A 1 171 ? 15.84205  -14.85524 56.97231 1.000 72.82828  ? 168 ARG A NH1   1 
ATOM   1353 N  NH2   . ARG A 1 171 ? 14.80103  -16.88490 57.16182 1.000 67.75468  ? 168 ARG A NH2   1 
ATOM   1354 N  N     . GLY A 1 172 ? 14.50145  -9.95774  51.37102 1.000 50.23712  ? 169 GLY A N     1 
ATOM   1355 C  CA    . GLY A 1 172 ? 14.95075  -8.83573  50.58004 1.000 48.61739  ? 169 GLY A CA    1 
ATOM   1356 C  C     . GLY A 1 172 ? 15.23618  -9.13877  49.12642 1.000 57.51316  ? 169 GLY A C     1 
ATOM   1357 O  O     . GLY A 1 172 ? 15.39678  -8.19741  48.33710 1.000 48.08737  ? 169 GLY A O     1 
ATOM   1358 N  N     . LYS A 1 173 ? 15.31036  -10.41092 48.74013 1.000 49.96365  ? 170 LYS A N     1 
ATOM   1359 C  CA    . LYS A 1 173 ? 15.50820  -10.74072 47.33902 1.000 46.38398  ? 170 LYS A CA    1 
ATOM   1360 C  C     . LYS A 1 173 ? 14.21967  -10.48100 46.56101 1.000 39.79491  ? 170 LYS A C     1 
ATOM   1361 O  O     . LYS A 1 173 ? 13.12564  -10.73740 47.06918 1.000 38.60084  ? 170 LYS A O     1 
ATOM   1362 C  CB    . LYS A 1 173 ? 15.92903  -12.19935 47.19008 1.000 44.45518  ? 170 LYS A CB    1 
ATOM   1363 C  CG    . LYS A 1 173 ? 17.27803  -12.50085 47.81902 1.000 52.71528  ? 170 LYS A CG    1 
ATOM   1364 C  CD    . LYS A 1 173 ? 17.87937  -13.79666 47.28797 1.000 61.05565  ? 170 LYS A CD    1 
ATOM   1365 C  CE    . LYS A 1 173 ? 19.36523  -13.61946 46.98299 1.000 66.45699  ? 170 LYS A CE    1 
ATOM   1366 N  NZ    . LYS A 1 173 ? 19.87647  -14.60949 45.99281 1.000 69.23475  ? 170 LYS A NZ    1 
ATOM   1367 N  N     . PRO A 1 174 ? 14.31193  -9.97318  45.33565 1.000 39.85948  ? 171 PRO A N     1 
ATOM   1368 C  CA    . PRO A 1 174 ? 13.10165  -9.69635  44.55703 1.000 36.58143  ? 171 PRO A CA    1 
ATOM   1369 C  C     . PRO A 1 174 ? 12.48270  -10.96449 43.98550 1.000 37.94883  ? 171 PRO A C     1 
ATOM   1370 O  O     . PRO A 1 174 ? 13.13119  -12.00208 43.84353 1.000 32.45911  ? 171 PRO A O     1 
ATOM   1371 C  CB    . PRO A 1 174 ? 13.59992  -8.77715  43.43527 1.000 42.44047  ? 171 PRO A CB    1 
ATOM   1372 C  CG    . PRO A 1 174 ? 15.10726  -8.95256  43.39593 1.000 49.26596  ? 171 PRO A CG    1 
ATOM   1373 C  CD    . PRO A 1 174 ? 15.53339  -9.84715  44.52110 1.000 39.12105  ? 171 PRO A CD    1 
ATOM   1374 N  N     . PHE A 1 175 ? 11.19344  -10.85822 43.66840 1.000 31.67539  ? 172 PHE A N     1 
ATOM   1375 C  CA    . PHE A 1 175 ? 10.49144  -11.93428 42.98126 1.000 33.15651  ? 172 PHE A CA    1 
ATOM   1376 C  C     . PHE A 1 175 ? 11.15959  -12.23052 41.64579 1.000 34.08245  ? 172 PHE A C     1 
ATOM   1377 O  O     . PHE A 1 175 ? 11.49834  -11.31720 40.89144 1.000 36.80275  ? 172 PHE A O     1 
ATOM   1378 C  CB    . PHE A 1 175 ? 9.02823   -11.54848 42.75617 1.000 27.84802  ? 172 PHE A CB    1 
ATOM   1379 C  CG    . PHE A 1 175 ? 8.26699   -12.50044 41.85963 1.000 28.18638  ? 172 PHE A CG    1 
ATOM   1380 C  CD1   . PHE A 1 175 ? 7.97318   -13.79599 42.28076 1.000 25.74090  ? 172 PHE A CD1   1 
ATOM   1381 C  CD2   . PHE A 1 175 ? 7.84038   -12.09888 40.60101 1.000 24.65874  ? 172 PHE A CD2   1 
ATOM   1382 C  CE1   . PHE A 1 175 ? 7.27058   -14.67269 41.46498 1.000 28.35269  ? 172 PHE A CE1   1 
ATOM   1383 C  CE2   . PHE A 1 175 ? 7.14337   -12.96828 39.77278 1.000 25.69456  ? 172 PHE A CE2   1 
ATOM   1384 C  CZ    . PHE A 1 175 ? 6.85786   -14.25613 40.19705 1.000 24.60824  ? 172 PHE A CZ    1 
ATOM   1385 N  N     . LYS A 1 176 ? 11.33456  -13.51425 41.35642 1.000 28.71074  ? 173 LYS A N     1 
ATOM   1386 C  CA    . LYS A 1 176 ? 11.93118  -13.98402 40.10529 1.000 31.53969  ? 173 LYS A CA    1 
ATOM   1387 C  C     . LYS A 1 176 ? 10.91402  -14.82746 39.34985 1.000 33.87327  ? 173 LYS A C     1 
ATOM   1388 O  O     . LYS A 1 176 ? 10.56734  -15.93034 39.81430 1.000 31.41729  ? 173 LYS A O     1 
ATOM   1389 C  CB    . LYS A 1 176 ? 13.18833  -14.80573 40.39045 1.000 39.21816  ? 173 LYS A CB    1 
ATOM   1390 C  CG    . LYS A 1 176 ? 14.04445  -15.08465 39.17131 1.000 44.52064  ? 173 LYS A CG    1 
ATOM   1391 C  CD    . LYS A 1 176 ? 15.50826  -15.21591 39.56874 1.000 60.26981  ? 173 LYS A CD    1 
ATOM   1392 C  CE    . LYS A 1 176 ? 16.07876  -13.88503 40.05023 1.000 64.04247  ? 173 LYS A CE    1 
ATOM   1393 N  NZ    . LYS A 1 176 ? 17.00607  -13.26235 39.06081 1.000 69.58523  ? 173 LYS A NZ    1 
ATOM   1394 N  N     . PRO A 1 177 ? 10.40819  -14.37972 38.20051 1.000 28.75778  ? 174 PRO A N     1 
ATOM   1395 C  CA    . PRO A 1 177 ? 9.34702   -15.13825 37.52556 1.000 29.61457  ? 174 PRO A CA    1 
ATOM   1396 C  C     . PRO A 1 177 ? 9.85901   -16.46721 36.98437 1.000 30.58988  ? 174 PRO A C     1 
ATOM   1397 O  O     . PRO A 1 177 ? 10.99363  -16.57443 36.51457 1.000 31.05732  ? 174 PRO A O     1 
ATOM   1398 C  CB    . PRO A 1 177 ? 8.90414   -14.20549 36.38934 1.000 31.66902  ? 174 PRO A CB    1 
ATOM   1399 C  CG    . PRO A 1 177 ? 10.07589  -13.31167 36.14858 1.000 33.42885  ? 174 PRO A CG    1 
ATOM   1400 C  CD    . PRO A 1 177 ? 10.75814  -13.14214 37.48468 1.000 31.45319  ? 174 PRO A CD    1 
ATOM   1401 N  N     . TRP A 1 178 ? 9.01127   -17.48886 37.07665 1.000 28.98022  ? 175 TRP A N     1 
ATOM   1402 C  CA    . TRP A 1 178 ? 9.32343   -18.77938 36.49117 1.000 31.85747  ? 175 TRP A CA    1 
ATOM   1403 C  C     . TRP A 1 178 ? 9.05341   -18.74946 34.99458 1.000 35.95623  ? 175 TRP A C     1 
ATOM   1404 O  O     . TRP A 1 178 ? 8.39633   -17.84802 34.46603 1.000 28.48871  ? 175 TRP A O     1 
ATOM   1405 C  CB    . TRP A 1 178 ? 8.49601   -19.88965 37.13359 1.000 29.88335  ? 175 TRP A CB    1 
ATOM   1406 C  CG    . TRP A 1 178 ? 7.07159   -19.49466 37.30508 1.000 26.17662  ? 175 TRP A CG    1 
ATOM   1407 C  CD1   . TRP A 1 178 ? 6.09566   -19.51935 36.35507 1.000 23.75213  ? 175 TRP A CD1   1 
ATOM   1408 C  CD2   . TRP A 1 178 ? 6.46799   -18.98090 38.49426 1.000 24.65653  ? 175 TRP A CD2   1 
ATOM   1409 N  NE1   . TRP A 1 178 ? 4.91733   -19.04635 36.88174 1.000 21.77790  ? 175 TRP A NE1   1 
ATOM   1410 C  CE2   . TRP A 1 178 ? 5.11846   -18.72275 38.19826 1.000 19.99837  ? 175 TRP A CE2   1 
ATOM   1411 C  CE3   . TRP A 1 178 ? 6.93826   -18.71892 39.78376 1.000 27.24626  ? 175 TRP A CE3   1 
ATOM   1412 C  CZ2   . TRP A 1 178 ? 4.23644   -18.22464 39.14243 1.000 21.04900  ? 175 TRP A CZ2   1 
ATOM   1413 C  CZ3   . TRP A 1 178 ? 6.05937   -18.21753 40.71690 1.000 23.62077  ? 175 TRP A CZ3   1 
ATOM   1414 C  CH2   . TRP A 1 178 ? 4.72782   -17.98040 40.39640 1.000 20.38161  ? 175 TRP A CH2   1 
ATOM   1415 N  N     . ASN A 1 179 ? 9.54068   -19.78033 34.31274 1.000 34.76298  ? 176 ASN A N     1 
ATOM   1416 C  CA    . ASN A 1 179 ? 9.41442   -19.82841 32.86790 1.000 40.89434  ? 176 ASN A CA    1 
ATOM   1417 C  C     . ASN A 1 179 ? 7.94709   -19.94159 32.47034 1.000 30.47338  ? 176 ASN A C     1 
ATOM   1418 O  O     . ASN A 1 179 ? 7.15095   -20.60326 33.14263 1.000 35.15119  ? 176 ASN A O     1 
ATOM   1419 C  CB    . ASN A 1 179 ? 10.24337  -20.99062 32.31644 1.000 43.94737  ? 176 ASN A CB    1 
ATOM   1420 C  CG    . ASN A 1 179 ? 10.00276  -21.23509 30.84007 1.000 54.12515  ? 176 ASN A CG    1 
ATOM   1421 O  OD1   . ASN A 1 179 ? 8.99480   -21.82324 30.45264 1.000 61.62960  ? 176 ASN A OD1   1 
ATOM   1422 N  ND2   . ASN A 1 179 ? 10.91021  -20.74220 30.00399 1.000 52.56435  ? 176 ASN A ND2   1 
ATOM   1423 N  N     . ASN A 1 180 ? 7.58392   -19.23526 31.39929 1.000 22.21398  ? 177 ASN A N     1 
ATOM   1424 C  CA    . ASN A 1 180 ? 6.25341   -19.27035 30.79248 1.000 24.81621  ? 177 ASN A CA    1 
ATOM   1425 C  C     . ASN A 1 180 ? 5.15552   -18.72632 31.69478 1.000 23.68213  ? 177 ASN A C     1 
ATOM   1426 O  O     . ASN A 1 180 ? 3.96777   -18.97434 31.44658 1.000 24.80506  ? 177 ASN A O     1 
ATOM   1427 C  CB    . ASN A 1 180 ? 5.90247   -20.68730 30.30729 1.000 38.31016  ? 177 ASN A CB    1 
ATOM   1428 C  CG    . ASN A 1 180 ? 6.67848   -21.06717 29.05159 1.000 36.13903  ? 177 ASN A CG    1 
ATOM   1429 O  OD1   . ASN A 1 180 ? 6.85854   -20.23828 28.16011 1.000 34.43952  ? 177 ASN A OD1   1 
ATOM   1430 N  ND2   . ASN A 1 180 ? 7.14111   -22.30156 28.97970 1.000 40.50557  ? 177 ASN A ND2   1 
ATOM   1431 N  N     . LEU A 1 181 ? 5.50942   -17.95566 32.71847 1.000 23.71657  ? 178 LEU A N     1 
ATOM   1432 C  CA    . LEU A 1 181 ? 4.47818   -17.25403 33.48234 1.000 21.28487  ? 178 LEU A CA    1 
ATOM   1433 C  C     . LEU A 1 181 ? 3.52808   -16.46570 32.58318 1.000 20.24932  ? 178 LEU A C     1 
ATOM   1434 O  O     . LEU A 1 181 ? 2.30730   -16.55356 32.79401 1.000 22.29643  ? 178 LEU A O     1 
ATOM   1435 C  CB    . LEU A 1 181 ? 5.14522   -16.36098 34.54480 1.000 17.25974  ? 178 LEU A CB    1 
ATOM   1436 C  CG    . LEU A 1 181 ? 4.27957   -15.71362 35.63674 1.000 18.26327  ? 178 LEU A CG    1 
ATOM   1437 C  CD1   . LEU A 1 181 ? 5.14914   -15.31598 36.83321 1.000 22.21798  ? 178 LEU A CD1   1 
ATOM   1438 C  CD2   . LEU A 1 181 ? 3.49632   -14.48638 35.13478 1.000 22.01319  ? 178 LEU A CD2   1 
ATOM   1439 N  N     . PRO A 1 182 ? 3.99278   -15.70511 31.55505 1.000 25.78314  ? 179 PRO A N     1 
ATOM   1440 C  CA    . PRO A 1 182 ? 3.03817   -14.94606 30.72740 1.000 25.41844  ? 179 PRO A CA    1 
ATOM   1441 C  C     . PRO A 1 182 ? 2.12030   -15.81959 29.89389 1.000 22.23444  ? 179 PRO A C     1 
ATOM   1442 O  O     . PRO A 1 182 ? 0.90928   -15.57623 29.82863 1.000 23.24589  ? 179 PRO A O     1 
ATOM   1443 C  CB    . PRO A 1 182 ? 3.94813   -14.09134 29.82885 1.000 26.77486  ? 179 PRO A CB    1 
ATOM   1444 C  CG    . PRO A 1 182 ? 5.23089   -13.99559 30.58111 1.000 25.02902  ? 179 PRO A CG    1 
ATOM   1445 C  CD    . PRO A 1 182 ? 5.38157   -15.35057 31.21337 1.000 26.21115  ? 179 PRO A CD    1 
ATOM   1446 N  N     . LYS A 1 183 ? 2.69087   -16.83649 29.23823 1.000 23.37929  ? 180 LYS A N     1 
ATOM   1447 C  CA    . LYS A 1 183 ? 1.87944   -17.74115 28.42631 1.000 27.64492  ? 180 LYS A CA    1 
ATOM   1448 C  C     . LYS A 1 183 ? 0.82298   -18.44667 29.26743 1.000 26.20992  ? 180 LYS A C     1 
ATOM   1449 O  O     . LYS A 1 183 ? -0.32308  -18.60188 28.83482 1.000 25.56617  ? 180 LYS A O     1 
ATOM   1450 C  CB    . LYS A 1 183 ? 2.77701   -18.76357 27.72535 1.000 28.46531  ? 180 LYS A CB    1 
ATOM   1451 C  CG    . LYS A 1 183 ? 2.93114   -18.51561 26.23222 1.000 44.87289  ? 180 LYS A CG    1 
ATOM   1452 C  CD    . LYS A 1 183 ? 3.61484   -19.69984 25.55450 1.000 57.67950  ? 180 LYS A CD    1 
ATOM   1453 C  CE    . LYS A 1 183 ? 3.22817   -19.79876 24.08692 1.000 52.09934  ? 180 LYS A CE    1 
ATOM   1454 N  NZ    . LYS A 1 183 ? 3.17855   -21.22150 23.61604 1.000 54.15343  ? 180 LYS A NZ    1 
ATOM   1455 N  N     . HIS A 1 184 ? 1.18536   -18.87602 30.47476 1.000 23.16789  ? 181 HIS A N     1 
ATOM   1456 C  CA    . HIS A 1 184 ? 0.19051   -19.47355 31.36332 1.000 23.32557  ? 181 HIS A CA    1 
ATOM   1457 C  C     . HIS A 1 184 ? -0.90687  -18.47520 31.70183 1.000 18.40814  ? 181 HIS A C     1 
ATOM   1458 O  O     . HIS A 1 184 ? -2.09739  -18.80511 31.66079 1.000 20.52166  ? 181 HIS A O     1 
ATOM   1459 C  CB    . HIS A 1 184 ? 0.85884   -19.98651 32.63897 1.000 19.21967  ? 181 HIS A CB    1 
ATOM   1460 C  CG    . HIS A 1 184 ? 1.88121   -21.04812 32.39845 1.000 20.20855  ? 181 HIS A CG    1 
ATOM   1461 N  ND1   . HIS A 1 184 ? 2.92360   -21.28499 33.26700 1.000 22.52987  ? 181 HIS A ND1   1 
ATOM   1462 C  CD2   . HIS A 1 184 ? 2.03181   -21.92943 31.37963 1.000 22.87430  ? 181 HIS A CD2   1 
ATOM   1463 C  CE1   . HIS A 1 184 ? 3.67021   -22.26818 32.79829 1.000 25.18012  ? 181 HIS A CE1   1 
ATOM   1464 N  NE2   . HIS A 1 184 ? 3.14933   -22.67897 31.65677 1.000 25.92131  ? 181 HIS A NE2   1 
ATOM   1465 N  N     . TYR A 1 185 ? -0.51803  -17.24599 32.05392 1.000 20.49883  ? 182 TYR A N     1 
ATOM   1466 C  CA    . TYR A 1 185 ? -1.50180  -16.22301 32.39143 1.000 21.11710  ? 182 TYR A CA    1 
ATOM   1467 C  C     . TYR A 1 185 ? -2.52084  -16.03078 31.26940 1.000 21.08230  ? 182 TYR A C     1 
ATOM   1468 O  O     . TYR A 1 185 ? -3.73470  -16.05001 31.50762 1.000 21.86657  ? 182 TYR A O     1 
ATOM   1469 C  CB    . TYR A 1 185 ? -0.80150  -14.89530 32.71312 1.000 23.29919  ? 182 TYR A CB    1 
ATOM   1470 C  CG    . TYR A 1 185 ? -1.80200  -13.75979 32.80032 1.000 23.31844  ? 182 TYR A CG    1 
ATOM   1471 C  CD1   . TYR A 1 185 ? -2.57079  -13.56979 33.94212 1.000 22.58079  ? 182 TYR A CD1   1 
ATOM   1472 C  CD2   . TYR A 1 185 ? -2.03134  -12.92059 31.70183 1.000 27.19866  ? 182 TYR A CD2   1 
ATOM   1473 C  CE1   . TYR A 1 185 ? -3.52198  -12.55219 34.01113 1.000 26.94812  ? 182 TYR A CE1   1 
ATOM   1474 C  CE2   . TYR A 1 185 ? -2.97587  -11.91206 31.76058 1.000 33.66815  ? 182 TYR A CE2   1 
ATOM   1475 C  CZ    . TYR A 1 185 ? -3.71416  -11.72893 32.91762 1.000 34.39232  ? 182 TYR A CZ    1 
ATOM   1476 O  OH    . TYR A 1 185 ? -4.64821  -10.71721 32.96512 1.000 41.77713  ? 182 TYR A OH    1 
ATOM   1477 N  N     . THR A 1 186 ? -2.04744  -15.84210 30.02867 1.000 23.37175  ? 183 THR A N     1 
ATOM   1478 C  CA    . THR A 1 186 ? -2.97902  -15.54726 28.93894 1.000 24.80430  ? 183 THR A CA    1 
ATOM   1479 C  C     . THR A 1 186 ? -3.94428  -16.70147 28.70249 1.000 25.17604  ? 183 THR A C     1 
ATOM   1480 O  O     . THR A 1 186 ? -5.13904  -16.48179 28.46822 1.000 26.00007  ? 183 THR A O     1 
ATOM   1481 C  CB    . THR A 1 186 ? -2.22259  -15.21848 27.64785 1.000 25.84058  ? 183 THR A CB    1 
ATOM   1482 O  OG1   . THR A 1 186 ? -1.42212  -16.34520 27.25579 1.000 31.81665  ? 183 THR A OG1   1 
ATOM   1483 C  CG2   . THR A 1 186 ? -1.34392  -14.00706 27.85237 1.000 31.00086  ? 183 THR A CG2   1 
ATOM   1484 N  N     . LEU A 1 187 ? -3.44836  -17.94501 28.78650 1.000 21.00282  ? 184 LEU A N     1 
ATOM   1485 C  CA    . LEU A 1 187 ? -4.31382  -19.10612 28.62417 1.000 20.83632  ? 184 LEU A CA    1 
ATOM   1486 C  C     . LEU A 1 187 ? -5.38588  -19.13818 29.70487 1.000 29.20585  ? 184 LEU A C     1 
ATOM   1487 O  O     . LEU A 1 187 ? -6.56810  -19.36594 29.42179 1.000 24.35534  ? 184 LEU A O     1 
ATOM   1488 C  CB    . LEU A 1 187 ? -3.48622  -20.40064 28.68464 1.000 24.96857  ? 184 LEU A CB    1 
ATOM   1489 C  CG    . LEU A 1 187 ? -3.00389  -21.16078 27.44785 1.000 33.08424  ? 184 LEU A CG    1 
ATOM   1490 C  CD1   . LEU A 1 187 ? -2.44025  -22.53479 27.86822 1.000 31.55415  ? 184 LEU A CD1   1 
ATOM   1491 C  CD2   . LEU A 1 187 ? -4.05811  -21.29109 26.33716 1.000 26.59126  ? 184 LEU A CD2   1 
ATOM   1492 N  N     . LEU A 1 188 ? -4.97568  -18.95322 30.96772 1.000 22.74200  ? 185 LEU A N     1 
ATOM   1493 C  CA    . LEU A 1 188 ? -5.92321  -18.98002 32.07683 1.000 18.78876  ? 185 LEU A CA    1 
ATOM   1494 C  C     . LEU A 1 188 ? -6.89105  -17.80844 32.00605 1.000 18.19329  ? 185 LEU A C     1 
ATOM   1495 O  O     . LEU A 1 188 ? -8.08304  -17.95294 32.31030 1.000 22.81120  ? 185 LEU A O     1 
ATOM   1496 C  CB    . LEU A 1 188 ? -5.16189  -18.94266 33.40493 1.000 18.56561  ? 185 LEU A CB    1 
ATOM   1497 C  CG    . LEU A 1 188 ? -4.33480  -20.19326 33.70463 1.000 21.72614  ? 185 LEU A CG    1 
ATOM   1498 C  CD1   . LEU A 1 188 ? -3.37103  -19.90565 34.85614 1.000 20.90676  ? 185 LEU A CD1   1 
ATOM   1499 C  CD2   . LEU A 1 188 ? -5.23411  -21.38870 34.02843 1.000 21.84968  ? 185 LEU A CD2   1 
ATOM   1500 N  N     . GLN A 1 189 ? -6.40040  -16.63375 31.62413 1.000 19.52513  ? 186 GLN A N     1 
ATOM   1501 C  CA    . GLN A 1 189 ? -7.29402  -15.47743 31.55456 1.000 24.52806  ? 186 GLN A CA    1 
ATOM   1502 C  C     . GLN A 1 189 ? -8.37967  -15.69715 30.50628 1.000 26.13242  ? 186 GLN A C     1 
ATOM   1503 O  O     . GLN A 1 189 ? -9.56076  -15.43070 30.75986 1.000 24.45795  ? 186 GLN A O     1 
ATOM   1504 C  CB    . GLN A 1 189 ? -6.50731  -14.20527 31.24552 1.000 27.39452  ? 186 GLN A CB    1 
ATOM   1505 C  CG    . GLN A 1 189 ? -7.41134  -13.04087 30.81872 1.000 35.97049  ? 186 GLN A CG    1 
ATOM   1506 C  CD    . GLN A 1 189 ? -6.64148  -11.83113 30.31951 1.000 53.73924  ? 186 GLN A CD    1 
ATOM   1507 O  OE1   . GLN A 1 189 ? -5.87418  -11.91852 29.35184 1.000 46.77365  ? 186 GLN A OE1   1 
ATOM   1508 N  NE2   . GLN A 1 189 ? -6.83542  -10.69115 30.98417 1.000 52.43475  ? 186 GLN A NE2   1 
ATOM   1509 N  N     . ALA A 1 190 ? -8.00454  -16.21410 29.32642 1.000 21.10014  ? 187 ALA A N     1 
ATOM   1510 C  CA    . ALA A 1 190 ? -9.01438  -16.53845 28.31631 1.000 26.13989  ? 187 ALA A CA    1 
ATOM   1511 C  C     . ALA A 1 190 ? -9.95909  -17.63256 28.79695 1.000 27.49266  ? 187 ALA A C     1 
ATOM   1512 O  O     . ALA A 1 190 ? -11.17019 -17.57191 28.54344 1.000 22.96212  ? 187 ALA A O     1 
ATOM   1513 C  CB    . ALA A 1 190 ? -8.34642  -16.95439 26.99925 1.000 26.22393  ? 187 ALA A CB    1 
ATOM   1514 N  N     . THR A 1 191 ? -9.42627  -18.64336 29.49302 1.000 25.81372  ? 188 THR A N     1 
ATOM   1515 C  CA    . THR A 1 191 ? -10.27452 -19.71922 30.00485 1.000 27.64691  ? 188 THR A CA    1 
ATOM   1516 C  C     . THR A 1 191 ? -11.25662 -19.21163 31.05892 1.000 23.26170  ? 188 THR A C     1 
ATOM   1517 O  O     . THR A 1 191 ? -12.42889 -19.61429 31.06784 1.000 24.32354  ? 188 THR A O     1 
ATOM   1518 C  CB    . THR A 1 191 ? -9.41482  -20.85228 30.57542 1.000 24.92516  ? 188 THR A CB    1 
ATOM   1519 O  OG1   . THR A 1 191 ? -8.55027  -21.34583 29.54970 1.000 27.64315  ? 188 THR A OG1   1 
ATOM   1520 C  CG2   . THR A 1 191 ? -10.28780 -21.99455 31.07810 1.000 24.75761  ? 188 THR A CG2   1 
ATOM   1521 N  N     . LEU A 1 192 ? -10.80382 -18.33254 31.95560 1.000 22.67097  ? 189 LEU A N     1 
ATOM   1522 C  CA    . LEU A 1 192 ? -11.70845 -17.77924 32.96327 1.000 22.71888  ? 189 LEU A CA    1 
ATOM   1523 C  C     . LEU A 1 192 ? -12.81880 -16.95774 32.31667 1.000 24.00035  ? 189 LEU A C     1 
ATOM   1524 O  O     . LEU A 1 192 ? -13.99623 -17.09545 32.67076 1.000 24.19987  ? 189 LEU A O     1 
ATOM   1525 C  CB    . LEU A 1 192 ? -10.92280 -16.93662 33.97079 1.000 22.38612  ? 189 LEU A CB    1 
ATOM   1526 C  CG    . LEU A 1 192 ? -11.73780 -16.33796 35.12658 1.000 25.98026  ? 189 LEU A CG    1 
ATOM   1527 C  CD1   . LEU A 1 192 ? -12.46078 -17.44308 35.90602 1.000 24.74891  ? 189 LEU A CD1   1 
ATOM   1528 C  CD2   . LEU A 1 192 ? -10.83712 -15.52212 36.04950 1.000 29.11795  ? 189 LEU A CD2   1 
ATOM   1529 N  N     . GLY A 1 193 ? -12.46509 -16.09169 31.36372 1.000 23.96117  ? 190 GLY A N     1 
ATOM   1530 C  CA    . GLY A 1 193 ? -13.49024 -15.31639 30.67956 1.000 28.70128  ? 190 GLY A CA    1 
ATOM   1531 C  C     . GLY A 1 193 ? -14.50017 -16.19759 29.97606 1.000 27.53776  ? 190 GLY A C     1 
ATOM   1532 O  O     . GLY A 1 193 ? -15.70433 -15.92069 29.98656 1.000 29.02007  ? 190 GLY A O     1 
ATOM   1533 N  N     . GLU A 1 194 ? -14.02070 -17.29162 29.38270 1.000 28.29071  ? 191 GLU A N     1 
ATOM   1534 C  CA    . GLU A 1 194 ? -14.88833 -18.27907 28.75482 1.000 30.81038  ? 191 GLU A CA    1 
ATOM   1535 C  C     . GLU A 1 194 ? -15.89275 -18.85409 29.74988 1.000 33.46232  ? 191 GLU A C     1 
ATOM   1536 O  O     . GLU A 1 194 ? -17.10382 -18.85912 29.49909 1.000 30.61064  ? 191 GLU A O     1 
ATOM   1537 C  CB    . GLU A 1 194 ? -14.01909 -19.39216 28.16893 1.000 35.56624  ? 191 GLU A CB    1 
ATOM   1538 C  CG    . GLU A 1 194 ? -14.36830 -19.89367 26.79662 1.000 44.08925  ? 191 GLU A CG    1 
ATOM   1539 C  CD    . GLU A 1 194 ? -13.43432 -21.03435 26.37857 1.000 50.79363  ? 191 GLU A CD    1 
ATOM   1540 O  OE1   . GLU A 1 194 ? -13.71721 -22.17454 26.79561 1.000 35.94731  ? 191 GLU A OE1   1 
ATOM   1541 O  OE2   . GLU A 1 194 ? -12.42970 -20.80296 25.65269 1.000 41.09555  ? 191 GLU A OE2   1 
ATOM   1542 N  N     . LEU A 1 195 ? -15.41047 -19.35280 30.89146 1.000 26.94462  ? 192 LEU A N     1 
ATOM   1543 C  CA    . LEU A 1 195 ? -16.31706 -20.04825 31.79720 1.000 27.91359  ? 192 LEU A CA    1 
ATOM   1544 C  C     . LEU A 1 195 ? -17.21617 -19.10189 32.58915 1.000 27.94320  ? 192 LEU A C     1 
ATOM   1545 O  O     . LEU A 1 195 ? -18.32764 -19.48708 32.96190 1.000 28.15254  ? 192 LEU A O     1 
ATOM   1546 C  CB    . LEU A 1 195 ? -15.52542 -20.96991 32.73252 1.000 34.98827  ? 192 LEU A CB    1 
ATOM   1547 C  CG    . LEU A 1 195 ? -14.74144 -20.37742 33.89482 1.000 34.55322  ? 192 LEU A CG    1 
ATOM   1548 C  CD1   . LEU A 1 195 ? -15.59595 -20.27865 35.15382 1.000 28.33718  ? 192 LEU A CD1   1 
ATOM   1549 C  CD2   . LEU A 1 195 ? -13.52415 -21.27435 34.14648 1.000 32.89949  ? 192 LEU A CD2   1 
ATOM   1550 N  N     . LEU A 1 196 ? -16.77479 -17.87807 32.85270 1.000 22.74824  ? 193 LEU A N     1 
ATOM   1551 C  CA    . LEU A 1 196 ? -17.66289 -16.88898 33.44170 1.000 29.70992  ? 193 LEU A CA    1 
ATOM   1552 C  C     . LEU A 1 196 ? -18.57930 -16.25584 32.40639 1.000 34.95778  ? 193 LEU A C     1 
ATOM   1553 O  O     . LEU A 1 196 ? -19.42698 -15.43119 32.77047 1.000 33.44213  ? 193 LEU A O     1 
ATOM   1554 C  CB    . LEU A 1 196 ? -16.85138 -15.79281 34.13959 1.000 30.62684  ? 193 LEU A CB    1 
ATOM   1555 C  CG    . LEU A 1 196 ? -16.05223 -16.17203 35.38837 1.000 29.49494  ? 193 LEU A CG    1 
ATOM   1556 C  CD1   . LEU A 1 196 ? -15.38824 -14.92875 35.96581 1.000 29.89988  ? 193 LEU A CD1   1 
ATOM   1557 C  CD2   . LEU A 1 196 ? -16.93113 -16.85020 36.42243 1.000 24.36866  ? 193 LEU A CD2   1 
ATOM   1558 N  N     . ARG A 1 197 ? -18.41612 -16.61169 31.13158 1.000 32.09121  ? 194 ARG A N     1 
ATOM   1559 C  CA    . ARG A 1 197 ? -19.21339 -16.04494 30.04766 1.000 35.03956  ? 194 ARG A CA    1 
ATOM   1560 C  C     . ARG A 1 197 ? -19.12590 -14.51645 30.04698 1.000 31.84744  ? 194 ARG A C     1 
ATOM   1561 O  O     . ARG A 1 197 ? -20.13879 -13.80858 30.02758 1.000 32.39435  ? 194 ARG A O     1 
ATOM   1562 C  CB    . ARG A 1 197 ? -20.66069 -16.53454 30.14649 1.000 32.35923  ? 194 ARG A CB    1 
ATOM   1563 C  CG    . ARG A 1 197 ? -20.75726 -18.06050 30.17794 1.000 35.16238  ? 194 ARG A CG    1 
ATOM   1564 C  CD    . ARG A 1 197 ? -22.18697 -18.55576 30.35416 1.000 40.25322  ? 194 ARG A CD    1 
ATOM   1565 N  NE    . ARG A 1 197 ? -22.27503 -20.00598 30.20474 1.000 39.73741  ? 194 ARG A NE    1 
ATOM   1566 C  CZ    . ARG A 1 197 ? -23.17204 -20.77822 30.80751 1.000 48.84776  ? 194 ARG A CZ    1 
ATOM   1567 N  NH1   . ARG A 1 197 ? -24.07099 -20.27683 31.64186 1.000 44.00425  ? 194 ARG A NH1   1 
ATOM   1568 N  NH2   . ARG A 1 197 ? -23.16995 -22.08853 30.56433 1.000 43.06843  ? 194 ARG A NH2   1 
ATOM   1569 N  N     . HIS A 1 198 ? -17.89246 -14.00673 30.10151 1.000 28.77153  ? 195 HIS A N     1 
ATOM   1570 C  CA    . HIS A 1 198 ? -17.67084 -12.56790 29.98101 1.000 30.64147  ? 195 HIS A CA    1 
ATOM   1571 C  C     . HIS A 1 198 ? -18.13363 -12.07247 28.62367 1.000 34.77676  ? 195 HIS A C     1 
ATOM   1572 O  O     . HIS A 1 198 ? -17.76947 -12.63575 27.58811 1.000 37.61076  ? 195 HIS A O     1 
ATOM   1573 C  CB    . HIS A 1 198 ? -16.19282 -12.20610 30.16608 1.000 38.90745  ? 195 HIS A CB    1 
ATOM   1574 C  CG    . HIS A 1 198 ? -15.71272 -12.23207 31.58639 1.000 47.73985  ? 195 HIS A CG    1 
ATOM   1575 N  ND1   . HIS A 1 198 ? -14.37141 -12.22514 31.91401 1.000 52.76437  ? 195 HIS A ND1   1 
ATOM   1576 C  CD2   . HIS A 1 198 ? -16.38523 -12.21055 32.76243 1.000 43.06480  ? 195 HIS A CD2   1 
ATOM   1577 C  CE1   . HIS A 1 198 ? -14.23948 -12.22947 33.22841 1.000 38.84425  ? 195 HIS A CE1   1 
ATOM   1578 N  NE2   . HIS A 1 198 ? -15.44669 -12.21252 33.76646 1.000 46.22619  ? 195 HIS A NE2   1 
ATOM   1579 N  N     . LEU A 1 199 ? -18.92171 -11.00524 28.63305 1.000 32.12515  ? 196 LEU A N     1 
ATOM   1580 C  CA    . LEU A 1 199 ? -19.41013 -10.38641 27.41268 1.000 36.84996  ? 196 LEU A CA    1 
ATOM   1581 C  C     . LEU A 1 199 ? -18.65515 -9.08918  27.17157 1.000 33.83818  ? 196 LEU A C     1 
ATOM   1582 O  O     . LEU A 1 199 ? -18.21918 -8.41263  28.10539 1.000 33.43196  ? 196 LEU A O     1 
ATOM   1583 C  CB    . LEU A 1 199 ? -20.90854 -10.10661 27.49988 1.000 39.25225  ? 196 LEU A CB    1 
ATOM   1584 C  CG    . LEU A 1 199 ? -21.82101 -11.30890 27.71664 1.000 37.20814  ? 196 LEU A CG    1 
ATOM   1585 C  CD1   . LEU A 1 199 ? -23.24640 -10.82934 27.94672 1.000 40.40622  ? 196 LEU A CD1   1 
ATOM   1586 C  CD2   . LEU A 1 199 ? -21.75068 -12.29480 26.56811 1.000 40.27535  ? 196 LEU A CD2   1 
ATOM   1587 N  N     . MET A 1 200 ? -18.49232 -8.74294  25.90950 1.000 30.67623  ? 197 MET A N     1 
ATOM   1588 C  CA    . MET A 1 200 ? -17.64477 -7.60970  25.59953 1.000 32.94417  ? 197 MET A CA    1 
ATOM   1589 C  C     . MET A 1 200 ? -18.46452 -6.32729  25.73453 1.000 33.09013  ? 197 MET A C     1 
ATOM   1590 O  O     . MET A 1 200 ? -19.67997 -6.31610  25.50976 1.000 30.05592  ? 197 MET A O     1 
ATOM   1591 C  CB    . MET A 1 200 ? -17.01861 -7.79673  24.20825 1.000 30.32067  ? 197 MET A CB    1 
ATOM   1592 C  CG    . MET A 1 200 ? -16.33835 -6.60639  23.59455 1.000 28.27802  ? 197 MET A CG    1 
ATOM   1593 S  SD    . MET A 1 200 ? -16.03163 -6.82225  21.82623 1.000 28.24797  ? 197 MET A SD    1 
ATOM   1594 C  CE    . MET A 1 200 ? -15.53176 -8.53558  21.65632 1.000 28.44860  ? 197 MET A CE    1 
ATOM   1595 N  N     . ASP A 1 201 ? -17.81409 -5.27252  26.20337 1.000 32.34986  ? 198 ASP A N     1 
ATOM   1596 C  CA    . ASP A 1 201 ? -18.49208 -3.99515  26.37692 1.000 31.91068  ? 198 ASP A CA    1 
ATOM   1597 C  C     . ASP A 1 201 ? -19.05172 -3.50423  25.03755 1.000 35.84132  ? 198 ASP A C     1 
ATOM   1598 O  O     . ASP A 1 201 ? -18.35773 -3.56717  24.01776 1.000 33.66271  ? 198 ASP A O     1 
ATOM   1599 C  CB    . ASP A 1 201 ? -17.50898 -2.97227  26.94466 1.000 38.15875  ? 198 ASP A CB    1 
ATOM   1600 C  CG    . ASP A 1 201 ? -18.07385 -1.58388  26.97205 1.000 41.06230  ? 198 ASP A CG    1 
ATOM   1601 O  OD1   . ASP A 1 201 ? -18.83633 -1.28828  27.91339 1.000 45.72084  ? 198 ASP A OD1   1 
ATOM   1602 O  OD2   . ASP A 1 201 ? -17.77134 -0.79738  26.05164 1.000 37.96921  ? 198 ASP A OD2   1 
ATOM   1603 N  N     . PRO A 1 202 ? -20.29232 -2.99429  25.00443 1.000 37.21784  ? 199 PRO A N     1 
ATOM   1604 C  CA    . PRO A 1 202 ? -20.89756 -2.61579  23.70945 1.000 33.43321  ? 199 PRO A CA    1 
ATOM   1605 C  C     . PRO A 1 202 ? -20.17416 -1.48417  22.99364 1.000 33.53035  ? 199 PRO A C     1 
ATOM   1606 O  O     . PRO A 1 202 ? -20.09450 -1.49317  21.75993 1.000 32.96309  ? 199 PRO A O     1 
ATOM   1607 C  CB    . PRO A 1 202 ? -22.32697 -2.19576  24.09524 1.000 38.19748  ? 199 PRO A CB    1 
ATOM   1608 C  CG    . PRO A 1 202 ? -22.51337 -2.64025  25.51631 1.000 46.96377  ? 199 PRO A CG    1 
ATOM   1609 C  CD    . PRO A 1 202 ? -21.16158 -2.63435  26.13744 1.000 41.94390  ? 199 PRO A CD    1 
ATOM   1610 N  N     . GLY A 1 203 ? -19.67473 -0.48874  23.73011 1.000 33.71134  ? 200 GLY A N     1 
ATOM   1611 C  CA    . GLY A 1 203 ? -18.88264 0.55386   23.09888 1.000 32.51256  ? 200 GLY A CA    1 
ATOM   1612 C  C     . GLY A 1 203 ? -17.57623 0.01412   22.55159 1.000 32.23769  ? 200 GLY A C     1 
ATOM   1613 O  O     . GLY A 1 203 ? -17.11348 0.43564   21.48804 1.000 29.34848  ? 200 GLY A O     1 
ATOM   1614 N  N     . THR A 1 204 ? -16.96439 -0.92668  23.27181 1.000 29.36447  ? 201 THR A N     1 
ATOM   1615 C  CA    . THR A 1 204 ? -15.74068 -1.55546  22.78500 1.000 24.67329  ? 201 THR A CA    1 
ATOM   1616 C  C     . THR A 1 204 ? -16.00052 -2.31499  21.49121 1.000 28.53416  ? 201 THR A C     1 
ATOM   1617 O  O     . THR A 1 204 ? -15.20531 -2.23729  20.54403 1.000 28.37926  ? 201 THR A O     1 
ATOM   1618 C  CB    . THR A 1 204 ? -15.18099 -2.49286  23.85937 1.000 33.06658  ? 201 THR A CB    1 
ATOM   1619 O  OG1   . THR A 1 204 ? -14.68746 -1.71153  24.95618 1.000 32.69012  ? 201 THR A OG1   1 
ATOM   1620 C  CG2   . THR A 1 204 ? -14.05946 -3.34048  23.30597 1.000 26.31490  ? 201 THR A CG2   1 
ATOM   1621 N  N     . PHE A 1 205 ? -17.11302 -3.05463  21.43355 1.000 24.47509  ? 202 PHE A N     1 
ATOM   1622 C  CA    . PHE A 1 205 ? -17.47689 -3.74621  20.20009 1.000 29.71223  ? 202 PHE A CA    1 
ATOM   1623 C  C     . PHE A 1 205 ? -17.65375 -2.76685  19.04821 1.000 29.18902  ? 202 PHE A C     1 
ATOM   1624 O  O     . PHE A 1 205 ? -17.02820 -2.91138  17.99256 1.000 25.88061  ? 202 PHE A O     1 
ATOM   1625 C  CB    . PHE A 1 205 ? -18.76005 -4.55606  20.38690 1.000 28.15591  ? 202 PHE A CB    1 
ATOM   1626 C  CG    . PHE A 1 205 ? -19.24006 -5.20522  19.11415 1.000 31.62409  ? 202 PHE A CG    1 
ATOM   1627 C  CD1   . PHE A 1 205 ? -18.63638 -6.36146  18.64521 1.000 29.95231  ? 202 PHE A CD1   1 
ATOM   1628 C  CD2   . PHE A 1 205 ? -20.25929 -4.63666  18.37000 1.000 31.24635  ? 202 PHE A CD2   1 
ATOM   1629 C  CE1   . PHE A 1 205 ? -19.05852 -6.95518  17.46110 1.000 28.25530  ? 202 PHE A CE1   1 
ATOM   1630 C  CE2   . PHE A 1 205 ? -20.68769 -5.22318  17.18488 1.000 32.71286  ? 202 PHE A CE2   1 
ATOM   1631 C  CZ    . PHE A 1 205 ? -20.08410 -6.39880  16.73547 1.000 31.33814  ? 202 PHE A CZ    1 
ATOM   1632 N  N     . THR A 1 206 ? -18.50725 -1.75680  19.23323 1.000 26.80130  ? 203 THR A N     1 
ATOM   1633 C  CA    . THR A 1 206 ? -18.82382 -0.85344  18.13288 1.000 28.88841  ? 203 THR A CA    1 
ATOM   1634 C  C     . THR A 1 206 ? -17.58608 -0.10405  17.66151 1.000 32.03107  ? 203 THR A C     1 
ATOM   1635 O  O     . THR A 1 206 ? -17.38100 0.07199   16.45684 1.000 30.08527  ? 203 THR A O     1 
ATOM   1636 C  CB    . THR A 1 206 ? -19.92360 0.11315   18.56354 1.000 34.20115  ? 203 THR A CB    1 
ATOM   1637 O  OG1   . THR A 1 206 ? -21.07631 -0.64816  18.94345 1.000 39.80304  ? 203 THR A OG1   1 
ATOM   1638 C  CG2   . THR A 1 206 ? -20.29883 1.05329   17.42738 1.000 38.19161  ? 203 THR A CG2   1 
ATOM   1639 N  N     . SER A 1 207 ? -16.72653 0.30763   18.59077 1.000 30.20599  ? 204 SER A N     1 
ATOM   1640 C  CA    . SER A 1 207 ? -15.53375 1.03715   18.18736 1.000 33.09693  ? 204 SER A CA    1 
ATOM   1641 C  C     . SER A 1 207 ? -14.56408 0.15016   17.43110 1.000 30.32110  ? 204 SER A C     1 
ATOM   1642 O  O     . SER A 1 207 ? -13.88670 0.62516   16.51474 1.000 26.31710  ? 204 SER A O     1 
ATOM   1643 C  CB    . SER A 1 207 ? -14.84091 1.64857   19.40290 1.000 31.93728  ? 204 SER A CB    1 
ATOM   1644 O  OG    . SER A 1 207 ? -15.66719 2.63542   19.98699 1.000 41.85216  ? 204 SER A OG    1 
ATOM   1645 N  N     . ASN A 1 208 ? -14.47861 -1.13159  17.78766 1.000 24.62695  ? 205 ASN A N     1 
ATOM   1646 C  CA    . ASN A 1 208 ? -13.45887 -1.97129  17.17756 1.000 23.03476  ? 205 ASN A CA    1 
ATOM   1647 C  C     . ASN A 1 208 ? -13.93175 -2.75349  15.96847 1.000 21.67539  ? 205 ASN A C     1 
ATOM   1648 O  O     . ASN A 1 208 ? -13.09072 -3.18678  15.17900 1.000 23.50182  ? 205 ASN A O     1 
ATOM   1649 C  CB    . ASN A 1 208 ? -12.87399 -2.93311  18.21082 1.000 20.89321  ? 205 ASN A CB    1 
ATOM   1650 C  CG    . ASN A 1 208 ? -11.93078 -2.23940  19.13158 1.000 30.46282  ? 205 ASN A CG    1 
ATOM   1651 O  OD1   . ASN A 1 208 ? -10.74774 -2.07559  18.80767 1.000 23.60347  ? 205 ASN A OD1   1 
ATOM   1652 N  ND2   . ASN A 1 208 ? -12.44730 -1.77109  20.27257 1.000 25.74300  ? 205 ASN A ND2   1 
ATOM   1653 N  N     . PHE A 1 209 ? -15.23358 -2.95329  15.79210 1.000 24.24962  ? 206 PHE A N     1 
ATOM   1654 C  CA    . PHE A 1 209 ? -15.70995 -3.70727  14.64050 1.000 26.37178  ? 206 PHE A CA    1 
ATOM   1655 C  C     . PHE A 1 209 ? -16.33203 -2.83773  13.56242 1.000 27.42241  ? 206 PHE A C     1 
ATOM   1656 O  O     . PHE A 1 209 ? -16.64581 -3.35041  12.48047 1.000 25.29451  ? 206 PHE A O     1 
ATOM   1657 C  CB    . PHE A 1 209 ? -16.69711 -4.78813  15.10067 1.000 22.14887  ? 206 PHE A CB    1 
ATOM   1658 C  CG    . PHE A 1 209 ? -16.00729 -5.98450  15.69030 1.000 27.46149  ? 206 PHE A CG    1 
ATOM   1659 C  CD1   . PHE A 1 209 ? -15.57268 -5.96331  17.00639 1.000 25.61814  ? 206 PHE A CD1   1 
ATOM   1660 C  CD2   . PHE A 1 209 ? -15.76072 -7.11535  14.92325 1.000 24.66000  ? 206 PHE A CD2   1 
ATOM   1661 C  CE1   . PHE A 1 209 ? -14.90621 -7.05110  17.55172 1.000 26.85713  ? 206 PHE A CE1   1 
ATOM   1662 C  CE2   . PHE A 1 209 ? -15.09899 -8.19853  15.45373 1.000 24.24181  ? 206 PHE A CE2   1 
ATOM   1663 C  CZ    . PHE A 1 209 ? -14.67510 -8.17262  16.77555 1.000 20.34000  ? 206 PHE A CZ    1 
ATOM   1664 N  N     . ASN A 1 210 ? -16.49377 -1.53914  13.80967 1.000 25.03773  ? 207 ASN A N     1 
ATOM   1665 C  CA    . ASN A 1 210 ? -16.87177 -0.62374  12.73961 1.000 25.28714  ? 207 ASN A CA    1 
ATOM   1666 C  C     . ASN A 1 210 ? -15.91600 -0.79847  11.55807 1.000 23.67161  ? 207 ASN A C     1 
ATOM   1667 O  O     . ASN A 1 210 ? -14.69364 -0.77129  11.72885 1.000 26.89988  ? 207 ASN A O     1 
ATOM   1668 C  CB    . ASN A 1 210 ? -16.84218 0.82066   13.27040 1.000 24.51287  ? 207 ASN A CB    1 
ATOM   1669 C  CG    . ASN A 1 210 ? -17.45873 1.82886   12.29660 1.000 30.44840  ? 207 ASN A CG    1 
ATOM   1670 O  OD1   . ASN A 1 210 ? -17.30364 1.71355   11.08082 1.000 29.04726  ? 207 ASN A OD1   1 
ATOM   1671 N  ND2   . ASN A 1 210 ? -18.16062 2.81831   12.83386 1.000 30.72635  ? 207 ASN A ND2   1 
ATOM   1672 N  N     . ASN A 1 211 ? -16.46687 -1.00562  10.35622 1.000 24.34500  ? 208 ASN A N     1 
ATOM   1673 C  CA    . ASN A 1 211 ? -15.63393 -1.37518  9.21548  1.000 24.27550  ? 208 ASN A CA    1 
ATOM   1674 C  C     . ASN A 1 211 ? -15.36314 -0.20377  8.27206  1.000 28.93825  ? 208 ASN A C     1 
ATOM   1675 O  O     . ASN A 1 211 ? -14.86202 -0.41584  7.16202  1.000 26.52361  ? 208 ASN A O     1 
ATOM   1676 C  CB    . ASN A 1 211 ? -16.23358 -2.56166  8.44220  1.000 24.32275  ? 208 ASN A CB    1 
ATOM   1677 C  CG    . ASN A 1 211 ? -17.62214 -2.29217  7.88187  1.000 30.40085  ? 208 ASN A CG    1 
ATOM   1678 O  OD1   . ASN A 1 211 ? -18.25363 -1.27449  8.16809  1.000 29.93107  ? 208 ASN A OD1   1 
ATOM   1679 N  ND2   . ASN A 1 211 ? -18.10469 -3.22220  7.06192  1.000 30.91655  ? 208 ASN A ND2   1 
ATOM   1680 N  N     . LYS A 1 212 ? -15.64245 1.02944   8.69523  1.000 27.22319  ? 209 LYS A N     1 
ATOM   1681 C  CA    . LYS A 1 212 ? -15.22802 2.17012   7.89457  1.000 28.15184  ? 209 LYS A CA    1 
ATOM   1682 C  C     . LYS A 1 212 ? -13.70502 2.29164   7.93954  1.000 23.87114  ? 209 LYS A C     1 
ATOM   1683 O  O     . LYS A 1 212 ? -13.05857 1.69945   8.80821  1.000 24.57149  ? 209 LYS A O     1 
ATOM   1684 C  CB    . LYS A 1 212 ? -15.90394 3.45117   8.39276  1.000 27.37856  ? 209 LYS A CB    1 
ATOM   1685 C  CG    . LYS A 1 212 ? -15.43425 3.94068   9.76693  1.000 30.86408  ? 209 LYS A CG    1 
ATOM   1686 C  CD    . LYS A 1 212 ? -16.30126 5.11814   10.24119 1.000 36.28458  ? 209 LYS A CD    1 
ATOM   1687 C  CE    . LYS A 1 212 ? -16.06999 5.44137   11.70968 1.000 40.84580  ? 209 LYS A CE    1 
ATOM   1688 N  NZ    . LYS A 1 212 ? -14.72749 6.02627   11.93460 1.000 42.04682  ? 209 LYS A NZ    1 
ATOM   1689 N  N     . PRO A 1 213 ? -13.10522 3.02265   6.99693  1.000 24.33872  ? 210 PRO A N     1 
ATOM   1690 C  CA    . PRO A 1 213 ? -11.65282 3.24408   7.05368  1.000 24.10053  ? 210 PRO A CA    1 
ATOM   1691 C  C     . PRO A 1 213 ? -11.20759 3.68855   8.44533  1.000 28.32817  ? 210 PRO A C     1 
ATOM   1692 O  O     . PRO A 1 213 ? -11.75509 4.62741   9.02254  1.000 27.26037  ? 210 PRO A O     1 
ATOM   1693 C  CB    . PRO A 1 213 ? -11.42815 4.34116   6.00768  1.000 27.99581  ? 210 PRO A CB    1 
ATOM   1694 C  CG    . PRO A 1 213 ? -12.49456 4.05584   4.98101  1.000 27.50623  ? 210 PRO A CG    1 
ATOM   1695 C  CD    . PRO A 1 213 ? -13.70307 3.65635   5.80297  1.000 26.09152  ? 210 PRO A CD    1 
ATOM   1696 N  N     . TRP A 1 214 ? -10.21019 2.99412   8.98080  1.000 26.21256  ? 211 TRP A N     1 
ATOM   1697 C  CA    . TRP A 1 214 ? -9.74431  3.22453   10.34722 1.000 21.99820  ? 211 TRP A CA    1 
ATOM   1698 C  C     . TRP A 1 214 ? -8.97007  4.53772   10.44275 1.000 29.04874  ? 211 TRP A C     1 
ATOM   1699 O  O     . TRP A 1 214 ? -8.05509  4.78269   9.65663  1.000 24.71414  ? 211 TRP A O     1 
ATOM   1700 C  CB    . TRP A 1 214 ? -8.85689  2.05724   10.77021 1.000 20.86251  ? 211 TRP A CB    1 
ATOM   1701 C  CG    . TRP A 1 214 ? -8.52153  2.00383   12.24290 1.000 22.10475  ? 211 TRP A CG    1 
ATOM   1702 C  CD1   . TRP A 1 214 ? -7.32251  2.30320   12.82090 1.000 20.83054  ? 211 TRP A CD1   1 
ATOM   1703 C  CD2   . TRP A 1 214 ? -9.39188  1.59749   13.30482 1.000 22.37632  ? 211 TRP A CD2   1 
ATOM   1704 N  NE1   . TRP A 1 214 ? -7.39452  2.11652   14.18566 1.000 21.80561  ? 211 TRP A NE1   1 
ATOM   1705 C  CE2   . TRP A 1 214 ? -8.65384  1.67672   14.50497 1.000 26.03445  ? 211 TRP A CE2   1 
ATOM   1706 C  CE3   . TRP A 1 214 ? -10.72670 1.17825   13.35938 1.000 22.76994  ? 211 TRP A CE3   1 
ATOM   1707 C  CZ2   . TRP A 1 214 ? -9.21335  1.36823   15.74180 1.000 22.67798  ? 211 TRP A CZ2   1 
ATOM   1708 C  CZ3   . TRP A 1 214 ? -11.27219 0.85961   14.58440 1.000 23.34327  ? 211 TRP A CZ3   1 
ATOM   1709 C  CH2   . TRP A 1 214 ? -10.52265 0.96776   15.75957 1.000 23.16458  ? 211 TRP A CH2   1 
ATOM   1710 N  N     . VAL A 1 215 ? -9.31510  5.37542   11.41857 1.000 25.13829  ? 212 VAL A N     1 
ATOM   1711 C  CA    . VAL A 1 215 ? -8.62980  6.65089   11.61008 1.000 24.46012  ? 212 VAL A CA    1 
ATOM   1712 C  C     . VAL A 1 215 ? -7.95284  6.78532   12.96938 1.000 22.75373  ? 212 VAL A C     1 
ATOM   1713 O  O     . VAL A 1 215 ? -7.20863  7.75419   13.17243 1.000 28.46238  ? 212 VAL A O     1 
ATOM   1714 C  CB    . VAL A 1 215 ? -9.58010  7.84864   11.38274 1.000 29.70581  ? 212 VAL A CB    1 
ATOM   1715 C  CG1   . VAL A 1 215 ? -9.91551  7.96881   9.90204  1.000 28.12179  ? 212 VAL A CG1   1 
ATOM   1716 C  CG2   . VAL A 1 215 ? -10.84325 7.66961   12.20347 1.000 33.75539  ? 212 VAL A CG2   1 
ATOM   1717 N  N     . SER A 1 216 ? -8.17785  5.87834   13.90596 1.000 22.85088  ? 213 SER A N     1 
ATOM   1718 C  CA    . SER A 1 216 ? -7.54280  5.99208   15.21538 1.000 25.50552  ? 213 SER A CA    1 
ATOM   1719 C  C     . SER A 1 216 ? -6.06618  5.61297   15.14781 1.000 26.28355  ? 213 SER A C     1 
ATOM   1720 O  O     . SER A 1 216 ? -5.64766  4.79693   14.32555 1.000 22.66796  ? 213 SER A O     1 
ATOM   1721 C  CB    . SER A 1 216 ? -8.25311  5.09855   16.23813 1.000 27.03169  ? 213 SER A CB    1 
ATOM   1722 O  OG    . SER A 1 216 ? -7.50024  4.99137   17.44103 1.000 25.75108  ? 213 SER A OG    1 
ATOM   1723 N  N     . GLY A 1 217 ? -5.26862  6.20575   16.03681 1.000 23.47483  ? 214 GLY A N     1 
ATOM   1724 C  CA    . GLY A 1 217 ? -3.88718  5.75577   16.15021 1.000 19.95218  ? 214 GLY A CA    1 
ATOM   1725 C  C     . GLY A 1 217 ? -3.71547  4.40630   16.83485 1.000 23.12766  ? 214 GLY A C     1 
ATOM   1726 O  O     . GLY A 1 217 ? -2.61632  3.84206   16.79169 1.000 20.31360  ? 214 GLY A O     1 
ATOM   1727 N  N     . GLN A 1 218 ? -4.76180  3.88768   17.46976 1.000 19.61944  ? 215 GLN A N     1 
ATOM   1728 C  CA    . GLN A 1 218 ? -4.66056  2.61681   18.18560 1.000 17.97127  ? 215 GLN A CA    1 
ATOM   1729 C  C     . GLN A 1 218 ? -4.62357  1.43665   17.22337 1.000 23.75977  ? 215 GLN A C     1 
ATOM   1730 O  O     . GLN A 1 218 ? -5.43779  1.35109   16.30036 1.000 18.78782  ? 215 GLN A O     1 
ATOM   1731 C  CB    . GLN A 1 218 ? -5.84431  2.43591   19.13508 1.000 24.18455  ? 215 GLN A CB    1 
ATOM   1732 C  CG    . GLN A 1 218 ? -5.74483  3.26204   20.40705 1.000 24.62279  ? 215 GLN A CG    1 
ATOM   1733 C  CD    . GLN A 1 218 ? -4.73861  2.66882   21.36080 1.000 27.88066  ? 215 GLN A CD    1 
ATOM   1734 O  OE1   . GLN A 1 218 ? -4.59966  1.44051   21.44924 1.000 26.51030  ? 215 GLN A OE1   1 
ATOM   1735 N  NE2   . GLN A 1 218 ? -3.99218  3.52987   22.04536 1.000 22.15181  ? 215 GLN A NE2   1 
ATOM   1736 N  N     . HIS A 1 219 ? -3.72141  0.49526   17.46985 1.000 21.59562  ? 216 HIS A N     1 
ATOM   1737 C  CA    . HIS A 1 219 ? -3.78736  -0.81074  16.80870 1.000 19.41049  ? 216 HIS A CA    1 
ATOM   1738 C  C     . HIS A 1 219 ? -4.04208  -1.86827  17.87622 1.000 24.02110  ? 216 HIS A C     1 
ATOM   1739 O  O     . HIS A 1 219 ? -3.11909  -2.28382  18.58131 1.000 19.86801  ? 216 HIS A O     1 
ATOM   1740 C  CB    . HIS A 1 219 ? -2.53156  -1.15044  16.01903 1.000 21.09991  ? 216 HIS A CB    1 
ATOM   1741 C  CG    . HIS A 1 219 ? -2.66851  -2.43496  15.25792 1.000 20.91916  ? 216 HIS A CG    1 
ATOM   1742 N  ND1   . HIS A 1 219 ? -3.43143  -2.53718  14.11320 1.000 22.65461  ? 216 HIS A ND1   1 
ATOM   1743 C  CD2   . HIS A 1 219 ? -2.22721  -3.68569  15.52877 1.000 21.16844  ? 216 HIS A CD2   1 
ATOM   1744 C  CE1   . HIS A 1 219 ? -3.40919  -3.78662  13.67912 1.000 24.08845  ? 216 HIS A CE1   1 
ATOM   1745 N  NE2   . HIS A 1 219 ? -2.68985  -4.50511  14.52307 1.000 23.21153  ? 216 HIS A NE2   1 
ATOM   1746 N  N     . GLU A 1 220 ? -5.30127  -2.27444  18.00199 1.000 20.85937  ? 217 GLU A N     1 
ATOM   1747 C  CA    . GLU A 1 220 ? -5.72698  -3.34834  18.88804 1.000 20.31426  ? 217 GLU A CA    1 
ATOM   1748 C  C     . GLU A 1 220 ? -6.58787  -4.30441  18.08053 1.000 22.11103  ? 217 GLU A C     1 
ATOM   1749 O  O     . GLU A 1 220 ? -7.28390  -3.88064  17.15293 1.000 19.65333  ? 217 GLU A O     1 
ATOM   1750 C  CB    . GLU A 1 220 ? -6.55231  -2.82775  20.07113 1.000 20.58004  ? 217 GLU A CB    1 
ATOM   1751 C  CG    . GLU A 1 220 ? -5.99796  -1.57308  20.76024 1.000 23.32382  ? 217 GLU A CG    1 
ATOM   1752 C  CD    . GLU A 1 220 ? -6.98616  -1.00110  21.74551 1.000 29.30214  ? 217 GLU A CD    1 
ATOM   1753 O  OE1   . GLU A 1 220 ? -7.94227  -0.31868  21.31528 1.000 27.30255  ? 217 GLU A OE1   1 
ATOM   1754 O  OE2   . GLU A 1 220 ? -6.81425  -1.24935  22.95196 1.000 27.91393  ? 217 GLU A OE2   1 
ATOM   1755 N  N     . THR A 1 221 ? -6.55309  -5.59249  18.43965 1.000 19.59667  ? 218 THR A N     1 
ATOM   1756 C  CA    . THR A 1 221 ? -7.34292  -6.60187  17.73394 1.000 21.85651  ? 218 THR A CA    1 
ATOM   1757 C  C     . THR A 1 221 ? -8.19515  -7.36456  18.73513 1.000 21.50316  ? 218 THR A C     1 
ATOM   1758 O  O     . THR A 1 221 ? -7.67004  -7.92460  19.70134 1.000 18.99252  ? 218 THR A O     1 
ATOM   1759 C  CB    . THR A 1 221 ? -6.45018  -7.56090  16.93819 1.000 24.96556  ? 218 THR A CB    1 
ATOM   1760 O  OG1   . THR A 1 221 ? -5.65123  -6.80385  16.01920 1.000 21.14394  ? 218 THR A OG1   1 
ATOM   1761 C  CG2   . THR A 1 221 ? -7.30382  -8.57671  16.15641 1.000 20.35869  ? 218 THR A CG2   1 
ATOM   1762 N  N     . TYR A 1 222 ? -9.50517  -7.36435  18.50619 1.000 22.61127  ? 219 TYR A N     1 
ATOM   1763 C  CA    . TYR A 1 222 ? -10.46924 -8.13018  19.27854 1.000 19.93607  ? 219 TYR A CA    1 
ATOM   1764 C  C     . TYR A 1 222 ? -10.93936 -9.30904  18.43612 1.000 21.48257  ? 219 TYR A C     1 
ATOM   1765 O  O     . TYR A 1 222 ? -11.18945 -9.16722  17.23579 1.000 20.59727  ? 219 TYR A O     1 
ATOM   1766 C  CB    . TYR A 1 222 ? -11.65666 -7.26028  19.68959 1.000 20.38845  ? 219 TYR A CB    1 
ATOM   1767 C  CG    . TYR A 1 222 ? -11.29464 -6.29113  20.81264 1.000 23.58005  ? 219 TYR A CG    1 
ATOM   1768 C  CD1   . TYR A 1 222 ? -10.61209 -5.10838  20.53390 1.000 24.75463  ? 219 TYR A CD1   1 
ATOM   1769 C  CD2   . TYR A 1 222 ? -11.61396 -6.56773  22.13555 1.000 26.07022  ? 219 TYR A CD2   1 
ATOM   1770 C  CE1   . TYR A 1 222 ? -10.26139 -4.22081  21.54573 1.000 30.82182  ? 219 TYR A CE1   1 
ATOM   1771 C  CE2   . TYR A 1 222 ? -11.26898 -5.67826  23.16048 1.000 26.09503  ? 219 TYR A CE2   1 
ATOM   1772 C  CZ    . TYR A 1 222 ? -10.59340 -4.50985  22.85288 1.000 30.85458  ? 219 TYR A CZ    1 
ATOM   1773 O  OH    . TYR A 1 222 ? -10.24726 -3.61393  23.84830 1.000 34.17282  ? 219 TYR A OH    1 
ATOM   1774 N  N     . LEU A 1 223 ? -11.04989 -10.47560 19.05875 1.000 20.25631  ? 220 LEU A N     1 
ATOM   1775 C  CA    . LEU A 1 223 ? -11.32195 -11.70025 18.31476 1.000 19.66441  ? 220 LEU A CA    1 
ATOM   1776 C  C     . LEU A 1 223 ? -12.37217 -12.50441 19.07158 1.000 22.70435  ? 220 LEU A C     1 
ATOM   1777 O  O     . LEU A 1 223 ? -12.15539 -12.86009 20.23403 1.000 22.45236  ? 220 LEU A O     1 
ATOM   1778 C  CB    . LEU A 1 223 ? -10.01958 -12.49827 18.12738 1.000 22.22032  ? 220 LEU A CB    1 
ATOM   1779 C  CG    . LEU A 1 223 ? -10.04997 -13.78767 17.28102 1.000 24.01959  ? 220 LEU A CG    1 
ATOM   1780 C  CD1   . LEU A 1 223 ? -8.68402  -14.07903 16.67231 1.000 24.56374  ? 220 LEU A CD1   1 
ATOM   1781 C  CD2   . LEU A 1 223 ? -10.51465 -14.99189 18.09267 1.000 21.86206  ? 220 LEU A CD2   1 
ATOM   1782 N  N     . CYS A 1 224 ? -13.51678 -12.74843 18.43558 1.000 21.42961  ? 221 CYS A N     1 
ATOM   1783 C  CA    . CYS A 1 224 ? -14.55817 -13.62639 18.96635 1.000 25.84449  ? 221 CYS A CA    1 
ATOM   1784 C  C     . CYS A 1 224 ? -14.45381 -14.99880 18.31242 1.000 26.73186  ? 221 CYS A C     1 
ATOM   1785 O  O     . CYS A 1 224 ? -14.17887 -15.10176 17.11416 1.000 25.13902  ? 221 CYS A O     1 
ATOM   1786 C  CB    . CYS A 1 224 ? -15.95546 -13.05143 18.70934 1.000 29.38532  ? 221 CYS A CB    1 
ATOM   1787 S  SG    . CYS A 1 224 ? -16.15417 -11.32580 19.22900 1.000 26.52024  ? 221 CYS A SG    1 
ATOM   1788 N  N     . TYR A 1 225 ? -14.68738 -16.05665 19.09097 1.000 22.22990  ? 222 TYR A N     1 
ATOM   1789 C  CA    . TYR A 1 225 ? -14.48646 -17.40198 18.56722 1.000 25.20233  ? 222 TYR A CA    1 
ATOM   1790 C  C     . TYR A 1 225 ? -15.62276 -18.33049 18.98656 1.000 26.61859  ? 222 TYR A C     1 
ATOM   1791 O  O     . TYR A 1 225 ? -16.29181 -18.12564 20.00346 1.000 26.13749  ? 222 TYR A O     1 
ATOM   1792 C  CB    . TYR A 1 225 ? -13.13093 -17.97890 19.01687 1.000 21.26373  ? 222 TYR A CB    1 
ATOM   1793 C  CG    . TYR A 1 225 ? -12.94753 -18.05369 20.51863 1.000 24.84424  ? 222 TYR A CG    1 
ATOM   1794 C  CD1   . TYR A 1 225 ? -13.39791 -19.16223 21.24227 1.000 28.10934  ? 222 TYR A CD1   1 
ATOM   1795 C  CD2   . TYR A 1 225 ? -12.30941 -17.03329 21.21425 1.000 25.80854  ? 222 TYR A CD2   1 
ATOM   1796 C  CE1   . TYR A 1 225 ? -13.22882 -19.24584 22.61784 1.000 26.11547  ? 222 TYR A CE1   1 
ATOM   1797 C  CE2   . TYR A 1 225 ? -12.13346 -17.10887 22.59714 1.000 27.02948  ? 222 TYR A CE2   1 
ATOM   1798 C  CZ    . TYR A 1 225 ? -12.59750 -18.21540 23.28627 1.000 32.48493  ? 222 TYR A CZ    1 
ATOM   1799 O  OH    . TYR A 1 225 ? -12.43191 -18.30030 24.64825 1.000 25.65986  ? 222 TYR A OH    1 
ATOM   1800 N  N     . LYS A 1 226 ? -15.82148 -19.37127 18.18332 1.000 27.98216  ? 223 LYS A N     1 
ATOM   1801 C  CA    . LYS A 1 226 ? -16.84543 -20.37137 18.44355 1.000 30.16329  ? 223 LYS A CA    1 
ATOM   1802 C  C     . LYS A 1 226 ? -16.41557 -21.66876 17.77990 1.000 32.87262  ? 223 LYS A C     1 
ATOM   1803 O  O     . LYS A 1 226 ? -15.57470 -21.67447 16.87522 1.000 29.80851  ? 223 LYS A O     1 
ATOM   1804 C  CB    . LYS A 1 226 ? -18.21643 -19.94351 17.91382 1.000 37.84112  ? 223 LYS A CB    1 
ATOM   1805 C  CG    . LYS A 1 226 ? -18.31356 -19.99742 16.39041 1.000 31.28570  ? 223 LYS A CG    1 
ATOM   1806 C  CD    . LYS A 1 226 ? -19.63670 -19.46837 15.89447 1.000 42.84978  ? 223 LYS A CD    1 
ATOM   1807 C  CE    . LYS A 1 226 ? -20.07477 -20.19497 14.63593 1.000 46.84523  ? 223 LYS A CE    1 
ATOM   1808 N  NZ    . LYS A 1 226 ? -21.54839 -20.14804 14.48401 1.000 50.43139  ? 223 LYS A NZ    1 
ATOM   1809 N  N     . VAL A 1 227 ? -17.01825 -22.77026 18.22684 1.000 32.56249  ? 224 VAL A N     1 
ATOM   1810 C  CA    . VAL A 1 227 ? -16.69869 -24.09303 17.70930 1.000 34.20011  ? 224 VAL A CA    1 
ATOM   1811 C  C     . VAL A 1 227 ? -17.98508 -24.82713 17.35078 1.000 39.00724  ? 224 VAL A C     1 
ATOM   1812 O  O     . VAL A 1 227 ? -19.01116 -24.68380 18.02545 1.000 35.52538  ? 224 VAL A O     1 
ATOM   1813 C  CB    . VAL A 1 227 ? -15.87493 -24.92342 18.71637 1.000 34.65009  ? 224 VAL A CB    1 
ATOM   1814 C  CG1   . VAL A 1 227 ? -15.37521 -26.22145 18.04483 1.000 31.59959  ? 224 VAL A CG1   1 
ATOM   1815 C  CG2   . VAL A 1 227 ? -14.71741 -24.10486 19.25063 1.000 31.95972  ? 224 VAL A CG2   1 
ATOM   1816 N  N     . GLU A 1 228 ? -17.91908 -25.61617 16.28751 1.000 36.72257  ? 225 GLU A N     1 
ATOM   1817 C  CA    . GLU A 1 228 ? -18.99145 -26.50879 15.87961 1.000 40.05693  ? 225 GLU A CA    1 
ATOM   1818 C  C     . GLU A 1 228 ? -18.40842 -27.88863 15.62917 1.000 40.69423  ? 225 GLU A C     1 
ATOM   1819 O  O     . GLU A 1 228 ? -17.22761 -28.03529 15.29830 1.000 40.49035  ? 225 GLU A O     1 
ATOM   1820 C  CB    . GLU A 1 228 ? -19.70505 -26.01397 14.61467 1.000 38.75117  ? 225 GLU A CB    1 
ATOM   1821 C  CG    . GLU A 1 228 ? -20.33827 -24.64177 14.74808 1.000 41.76735  ? 225 GLU A CG    1 
ATOM   1822 C  CD    . GLU A 1 228 ? -20.64165 -24.03705 13.39255 1.000 49.21749  ? 225 GLU A CD    1 
ATOM   1823 O  OE1   . GLU A 1 228 ? -19.67782 -23.64749 12.69913 1.000 49.22343  ? 225 GLU A OE1   1 
ATOM   1824 O  OE2   . GLU A 1 228 ? -21.83010 -24.00004 13.00151 1.000 47.67697  ? 225 GLU A OE2   1 
ATOM   1825 N  N     . ARG A 1 229 ? -19.26404 -28.89599 15.78068 1.000 38.99502  ? 226 ARG A N     1 
ATOM   1826 C  CA    . ARG A 1 229 ? -18.90006 -30.29800 15.62284 1.000 43.98136  ? 226 ARG A CA    1 
ATOM   1827 C  C     . ARG A 1 229 ? -19.67422 -30.88926 14.45475 1.000 44.52058  ? 226 ARG A C     1 
ATOM   1828 O  O     . ARG A 1 229 ? -20.83495 -30.53649 14.22825 1.000 47.69112  ? 226 ARG A O     1 
ATOM   1829 C  CB    . ARG A 1 229 ? -19.20072 -31.08435 16.91000 1.000 49.31158  ? 226 ARG A CB    1 
ATOM   1830 C  CG    . ARG A 1 229 ? -18.71383 -32.52655 16.92767 1.000 55.65003  ? 226 ARG A CG    1 
ATOM   1831 C  CD    . ARG A 1 229 ? -19.00421 -33.18448 18.27644 1.000 53.40586  ? 226 ARG A CD    1 
ATOM   1832 N  NE    . ARG A 1 229 ? -20.41739 -33.10323 18.63566 1.000 60.04926  ? 226 ARG A NE    1 
ATOM   1833 C  CZ    . ARG A 1 229 ? -21.35986 -33.91078 18.16245 1.000 68.82920  ? 226 ARG A CZ    1 
ATOM   1834 N  NH1   . ARG A 1 229 ? -21.07741 -34.87731 17.30166 1.000 63.24461  ? 226 ARG A NH1   1 
ATOM   1835 N  NH2   . ARG A 1 229 ? -22.61808 -33.74448 18.56190 1.000 70.73405  ? 226 ARG A NH2   1 
ATOM   1836 N  N     . LEU A 1 230 ? -19.02616 -31.77542 13.70081 1.000 47.68044  ? 227 LEU A N     1 
ATOM   1837 C  CA    . LEU A 1 230 ? -19.69767 -32.48743 12.61929 1.000 53.02782  ? 227 LEU A CA    1 
ATOM   1838 C  C     . LEU A 1 230 ? -20.48720 -33.65682 13.19914 1.000 56.74572  ? 227 LEU A C     1 
ATOM   1839 O  O     . LEU A 1 230 ? -19.90242 -34.57333 13.78490 1.000 58.70071  ? 227 LEU A O     1 
ATOM   1840 C  CB    . LEU A 1 230 ? -18.68340 -32.98722 11.59318 1.000 52.20707  ? 227 LEU A CB    1 
ATOM   1841 C  CG    . LEU A 1 230 ? -19.20204 -33.28089 10.18162 1.000 58.50978  ? 227 LEU A CG    1 
ATOM   1842 C  CD1   . LEU A 1 230 ? -20.19142 -32.20502 9.71233  1.000 55.60791  ? 227 LEU A CD1   1 
ATOM   1843 C  CD2   . LEU A 1 230 ? -18.04595 -33.45467 9.20365  1.000 52.24229  ? 227 LEU A CD2   1 
ATOM   1844 N  N     . HIS A 1 231 ? -21.81034 -33.62618 13.03502 1.000 63.44296  ? 228 HIS A N     1 
ATOM   1845 C  CA    . HIS A 1 231 ? -22.69261 -34.68846 13.51744 1.000 69.38859  ? 228 HIS A CA    1 
ATOM   1846 C  C     . HIS A 1 231 ? -23.70270 -35.00881 12.42287 1.000 77.87693  ? 228 HIS A C     1 
ATOM   1847 O  O     . HIS A 1 231 ? -24.56586 -34.18067 12.11359 1.000 75.55887  ? 228 HIS A O     1 
ATOM   1848 C  CB    . HIS A 1 231 ? -23.39921 -34.27802 14.81125 1.000 72.44749  ? 228 HIS A CB    1 
ATOM   1849 C  CG    . HIS A 1 231 ? -24.16280 -35.38989 15.46479 1.000 87.45471  ? 228 HIS A CG    1 
ATOM   1850 N  ND1   . HIS A 1 231 ? -23.57862 -36.58549 15.82708 1.000 85.73270  ? 228 HIS A ND1   1 
ATOM   1851 C  CD2   . HIS A 1 231 ? -25.46676 -35.48666 15.81892 1.000 88.57995  ? 228 HIS A CD2   1 
ATOM   1852 C  CE1   . HIS A 1 231 ? -24.48909 -37.36901 16.37752 1.000 90.22710  ? 228 HIS A CE1   1 
ATOM   1853 N  NE2   . HIS A 1 231 ? -25.64347 -36.72644 16.38368 1.000 89.11652  ? 228 HIS A NE2   1 
ATOM   1854 N  N     . ASN A 1 232 ? -23.59932 -36.21051 11.84803 1.000 73.55854  ? 229 ASN A N     1 
ATOM   1855 C  CA    . ASN A 1 232 ? -24.47900 -36.65631 10.76290 1.000 75.39519  ? 229 ASN A CA    1 
ATOM   1856 C  C     . ASN A 1 232 ? -24.44387 -35.68041 9.58737  1.000 73.71560  ? 229 ASN A C     1 
ATOM   1857 O  O     . ASN A 1 232 ? -25.47801 -35.19699 9.12123  1.000 73.15926  ? 229 ASN A O     1 
ATOM   1858 C  CB    . ASN A 1 232 ? -25.91672 -36.86889 11.25347 1.000 71.78360  ? 229 ASN A CB    1 
ATOM   1859 C  CG    . ASN A 1 232 ? -26.02484 -37.95670 12.31302 1.000 79.14800  ? 229 ASN A CG    1 
ATOM   1860 O  OD1   . ASN A 1 232 ? -25.29251 -38.94672 12.28132 1.000 81.39897  ? 229 ASN A OD1   1 
ATOM   1861 N  ND2   . ASN A 1 232 ? -26.95845 -37.78631 13.24470 1.000 77.40815  ? 229 ASN A ND2   1 
ATOM   1862 N  N     . ASP A 1 233 ? -23.22989 -35.39258 9.11043  1.000 78.66112  ? 230 ASP A N     1 
ATOM   1863 C  CA    . ASP A 1 233 ? -23.01297 -34.49093 7.97394  1.000 83.33299  ? 230 ASP A CA    1 
ATOM   1864 C  C     . ASP A 1 233 ? -23.70866 -33.14709 8.18915  1.000 80.39982  ? 230 ASP A C     1 
ATOM   1865 O  O     . ASP A 1 233 ? -24.26728 -32.55179 7.26586  1.000 79.72480  ? 230 ASP A O     1 
ATOM   1866 C  CB    . ASP A 1 233 ? -23.46278 -35.13917 6.66337  1.000 93.91136  ? 230 ASP A CB    1 
ATOM   1867 C  CG    . ASP A 1 233 ? -22.39253 -36.02835 6.05805  1.000 102.55301 ? 230 ASP A CG    1 
ATOM   1868 O  OD1   . ASP A 1 233 ? -21.34178 -35.49257 5.64705  1.000 102.45760 ? 230 ASP A OD1   1 
ATOM   1869 O  OD2   . ASP A 1 233 ? -22.59989 -37.26032 5.99412  1.000 103.66828 ? 230 ASP A OD2   1 
ATOM   1870 N  N     . THR A 1 234 ? -23.67115 -32.66773 9.42960  1.000 78.49737  ? 231 THR A N     1 
ATOM   1871 C  CA    . THR A 1 234 ? -24.29921 -31.41398 9.81571  1.000 68.53534  ? 231 THR A CA    1 
ATOM   1872 C  C     . THR A 1 234 ? -23.43210 -30.76426 10.88114 1.000 60.37313  ? 231 THR A C     1 
ATOM   1873 O  O     . THR A 1 234 ? -22.87644 -31.45461 11.73845 1.000 61.36894  ? 231 THR A O     1 
ATOM   1874 C  CB    . THR A 1 234 ? -25.71904 -31.63416 10.35676 1.000 70.89130  ? 231 THR A CB    1 
ATOM   1875 O  OG1   . THR A 1 234 ? -26.44460 -32.49530 9.46861  1.000 82.47330  ? 231 THR A OG1   1 
ATOM   1876 C  CG2   . THR A 1 234 ? -26.45757 -30.31161 10.49443 1.000 56.23162  ? 231 THR A CG2   1 
ATOM   1877 N  N     . TRP A 1 235 ? -23.31921 -29.44186 10.82386 1.000 58.36069  ? 232 TRP A N     1 
ATOM   1878 C  CA    . TRP A 1 235 ? -22.54860 -28.68853 11.80475 1.000 56.88347  ? 232 TRP A CA    1 
ATOM   1879 C  C     . TRP A 1 235 ? -23.45497 -28.31498 12.97336 1.000 56.48414  ? 232 TRP A C     1 
ATOM   1880 O  O     . TRP A 1 235 ? -24.44248 -27.59448 12.79477 1.000 61.53811  ? 232 TRP A O     1 
ATOM   1881 C  CB    . TRP A 1 235 ? -21.94033 -27.44297 11.16329 1.000 49.58057  ? 232 TRP A CB    1 
ATOM   1882 C  CG    . TRP A 1 235 ? -20.76833 -27.73320 10.26520 1.000 48.01064  ? 232 TRP A CG    1 
ATOM   1883 C  CD1   . TRP A 1 235 ? -20.68470 -27.48897 8.92434  1.000 54.31866  ? 232 TRP A CD1   1 
ATOM   1884 C  CD2   . TRP A 1 235 ? -19.50457 -28.29153 10.64856 1.000 41.79732  ? 232 TRP A CD2   1 
ATOM   1885 N  NE1   . TRP A 1 235 ? -19.45416 -27.87136 8.44834  1.000 52.92395  ? 232 TRP A NE1   1 
ATOM   1886 C  CE2   . TRP A 1 235 ? -18.71186 -28.36864 9.48714  1.000 45.34307  ? 232 TRP A CE2   1 
ATOM   1887 C  CE3   . TRP A 1 235 ? -18.96945 -28.73986 11.86046 1.000 43.80278  ? 232 TRP A CE3   1 
ATOM   1888 C  CZ2   . TRP A 1 235 ? -17.41239 -28.87410 9.50132  1.000 54.82650  ? 232 TRP A CZ2   1 
ATOM   1889 C  CZ3   . TRP A 1 235 ? -17.67840 -29.24389 11.87217 1.000 43.24993  ? 232 TRP A CZ3   1 
ATOM   1890 C  CH2   . TRP A 1 235 ? -16.91500 -29.30473 10.70219 1.000 42.88023  ? 232 TRP A CH2   1 
ATOM   1891 N  N     . VAL A 1 236 ? -23.12956 -28.81716 14.15915 1.000 49.97968  ? 233 VAL A N     1 
ATOM   1892 C  CA    . VAL A 1 236 ? -23.91591 -28.54533 15.36081 1.000 58.38489  ? 233 VAL A CA    1 
ATOM   1893 C  C     . VAL A 1 236 ? -23.07150 -27.67288 16.28363 1.000 56.63015  ? 233 VAL A C     1 
ATOM   1894 O  O     . VAL A 1 236 ? -21.84478 -27.84682 16.34345 1.000 51.17234  ? 233 VAL A O     1 
ATOM   1895 C  CB    . VAL A 1 236 ? -24.36482 -29.85219 16.04667 1.000 57.55263  ? 233 VAL A CB    1 
ATOM   1896 C  CG1   . VAL A 1 236 ? -23.20571 -30.82063 16.18684 1.000 53.69369  ? 233 VAL A CG1   1 
ATOM   1897 C  CG2   . VAL A 1 236 ? -24.98595 -29.58065 17.40776 1.000 58.54762  ? 233 VAL A CG2   1 
ATOM   1898 N  N     . PRO A 1 237 ? -23.66604 -26.70531 16.98124 1.000 58.37853  ? 234 PRO A N     1 
ATOM   1899 C  CA    . PRO A 1 237 ? -22.88618 -25.90035 17.92929 1.000 58.27877  ? 234 PRO A CA    1 
ATOM   1900 C  C     . PRO A 1 237 ? -22.24781 -26.75514 19.01174 1.000 60.37008  ? 234 PRO A C     1 
ATOM   1901 O  O     . PRO A 1 237 ? -22.83549 -27.72415 19.49735 1.000 62.65598  ? 234 PRO A O     1 
ATOM   1902 C  CB    . PRO A 1 237 ? -23.91606 -24.92999 18.52197 1.000 61.64147  ? 234 PRO A CB    1 
ATOM   1903 C  CG    . PRO A 1 237 ? -25.11125 -24.99421 17.65165 1.000 64.83195  ? 234 PRO A CG    1 
ATOM   1904 C  CD    . PRO A 1 237 ? -25.01709 -26.16950 16.73926 1.000 64.85246  ? 234 PRO A CD    1 
ATOM   1905 N  N     . LEU A 1 238 ? -21.02211 -26.39176 19.37135 1.000 55.98181  ? 235 LEU A N     1 
ATOM   1906 C  CA    . LEU A 1 238 ? -20.34377 -26.90845 20.55597 1.000 58.40244  ? 235 LEU A CA    1 
ATOM   1907 C  C     . LEU A 1 238 ? -20.33578 -25.76944 21.56760 1.000 66.82181  ? 235 LEU A C     1 
ATOM   1908 O  O     . LEU A 1 238 ? -19.48432 -24.87723 21.50740 1.000 73.45295  ? 235 LEU A O     1 
ATOM   1909 C  CB    . LEU A 1 238 ? -18.93200 -27.38212 20.23168 1.000 58.52202  ? 235 LEU A CB    1 
ATOM   1910 C  CG    . LEU A 1 238 ? -18.27841 -28.26657 21.29488 1.000 56.49803  ? 235 LEU A CG    1 
ATOM   1911 C  CD1   . LEU A 1 238 ? -18.64960 -29.73307 21.08692 1.000 62.02568  ? 235 LEU A CD1   1 
ATOM   1912 C  CD2   . LEU A 1 238 ? -16.77028 -28.07565 21.31972 1.000 51.80002  ? 235 LEU A CD2   1 
ATOM   1913 N  N     . ASN A 1 239 ? -21.28947 -25.80116 22.49579 1.000 70.28795  ? 236 ASN A N     1 
ATOM   1914 C  CA    . ASN A 1 239 ? -21.53376 -24.67616 23.39069 1.000 80.83699  ? 236 ASN A CA    1 
ATOM   1915 C  C     . ASN A 1 239 ? -20.40171 -24.41465 24.38090 1.000 79.40234  ? 236 ASN A C     1 
ATOM   1916 O  O     . ASN A 1 239 ? -20.46251 -23.41255 25.10191 1.000 76.49292  ? 236 ASN A O     1 
ATOM   1917 C  CB    . ASN A 1 239 ? -22.83708 -24.91961 24.14801 1.000 86.94278  ? 236 ASN A CB    1 
ATOM   1918 C  CG    . ASN A 1 239 ? -22.96060 -26.35156 24.63765 1.000 90.08619  ? 236 ASN A CG    1 
ATOM   1919 O  OD1   . ASN A 1 239 ? -22.18902 -26.79824 25.48797 1.000 89.30713  ? 236 ASN A OD1   1 
ATOM   1920 N  ND2   . ASN A 1 239 ? -23.92294 -27.08462 24.08786 1.000 91.62977  ? 236 ASN A ND2   1 
ATOM   1921 N  N     . GLN A 1 240 ? -19.37132 -25.26337 24.42577 1.000 65.60290  ? 237 GLN A N     1 
ATOM   1922 C  CA    . GLN A 1 240 ? -18.38860 -25.17305 25.50163 1.000 67.39889  ? 237 GLN A CA    1 
ATOM   1923 C  C     . GLN A 1 240 ? -17.37219 -24.05475 25.28517 1.000 67.58774  ? 237 GLN A C     1 
ATOM   1924 O  O     . GLN A 1 240 ? -17.02100 -23.34450 26.23636 1.000 67.09601  ? 237 GLN A O     1 
ATOM   1925 C  CB    . GLN A 1 240 ? -17.66809 -26.51044 25.66705 1.000 67.04111  ? 237 GLN A CB    1 
ATOM   1926 C  CG    . GLN A 1 240 ? -18.52442 -27.58803 26.30828 1.000 79.48727  ? 237 GLN A CG    1 
ATOM   1927 C  CD    . GLN A 1 240 ? -19.00747 -28.62047 25.31258 1.000 79.66217  ? 237 GLN A CD    1 
ATOM   1928 O  OE1   . GLN A 1 240 ? -18.20853 -29.30349 24.67452 1.000 83.75667  ? 237 GLN A OE1   1 
ATOM   1929 N  NE2   . GLN A 1 240 ? -20.32309 -28.73284 25.16601 1.000 82.52719  ? 237 GLN A NE2   1 
ATOM   1930 N  N     . HIS A 1 241 ? -16.87744 -23.88244 24.06154 1.000 49.23196  ? 238 HIS A N     1 
ATOM   1931 C  CA    . HIS A 1 241 ? -15.70338 -23.04347 23.81633 1.000 38.80125  ? 238 HIS A CA    1 
ATOM   1932 C  C     . HIS A 1 241 ? -16.12058 -21.85276 22.96266 1.000 37.58744  ? 238 HIS A C     1 
ATOM   1933 O  O     . HIS A 1 241 ? -15.92130 -21.83661 21.74693 1.000 30.74872  ? 238 HIS A O     1 
ATOM   1934 C  CB    . HIS A 1 241 ? -14.61823 -23.86843 23.15921 1.000 38.43589  ? 238 HIS A CB    1 
ATOM   1935 C  CG    . HIS A 1 241 ? -14.17236 -25.02716 23.99479 1.000 44.35859  ? 238 HIS A CG    1 
ATOM   1936 N  ND1   . HIS A 1 241 ? -13.70631 -24.87923 25.28520 1.000 47.26159  ? 238 HIS A ND1   1 
ATOM   1937 C  CD2   . HIS A 1 241 ? -14.14881 -26.35543 23.73466 1.000 45.23293  ? 238 HIS A CD2   1 
ATOM   1938 C  CE1   . HIS A 1 241 ? -13.40025 -26.06759 25.77812 1.000 38.89461  ? 238 HIS A CE1   1 
ATOM   1939 N  NE2   . HIS A 1 241 ? -13.66247 -26.97854 24.85786 1.000 38.94148  ? 238 HIS A NE2   1 
ATOM   1940 N  N     . ARG A 1 242 ? -16.69688 -20.85007 23.61831 1.000 30.64074  ? 239 ARG A N     1 
ATOM   1941 C  CA    . ARG A 1 242 ? -17.23852 -19.67458 22.95830 1.000 33.06604  ? 239 ARG A CA    1 
ATOM   1942 C  C     . ARG A 1 242 ? -16.87781 -18.46753 23.81105 1.000 27.90336  ? 239 ARG A C     1 
ATOM   1943 O  O     . ARG A 1 242 ? -17.10771 -18.47962 25.02248 1.000 34.98042  ? 239 ARG A O     1 
ATOM   1944 C  CB    . ARG A 1 242 ? -18.75507 -19.82202 22.80369 1.000 35.35091  ? 239 ARG A CB    1 
ATOM   1945 C  CG    . ARG A 1 242 ? -19.39755 -18.91712 21.78366 1.000 44.07948  ? 239 ARG A CG    1 
ATOM   1946 C  CD    . ARG A 1 242 ? -20.88525 -19.21666 21.70356 1.000 49.99898  ? 239 ARG A CD    1 
ATOM   1947 N  NE    . ARG A 1 242 ? -21.62125 -18.54265 22.76722 1.000 55.34691  ? 239 ARG A NE    1 
ATOM   1948 C  CZ    . ARG A 1 242 ? -22.93169 -18.63392 22.94785 1.000 52.84013  ? 239 ARG A CZ    1 
ATOM   1949 N  NH1   . ARG A 1 242 ? -23.68812 -19.38175 22.16021 1.000 54.08557  ? 239 ARG A NH1   1 
ATOM   1950 N  NH2   . ARG A 1 242 ? -23.49831 -17.95158 23.93943 1.000 63.30618  ? 239 ARG A NH2   1 
ATOM   1951 N  N     . GLY A 1 243 ? -16.28200 -17.45054 23.20272 1.000 27.10018  ? 240 GLY A N     1 
ATOM   1952 C  CA    . GLY A 1 243 ? -15.84987 -16.29793 23.97653 1.000 19.29189  ? 240 GLY A CA    1 
ATOM   1953 C  C     . GLY A 1 243 ? -15.13790 -15.28998 23.10563 1.000 24.34361  ? 240 GLY A C     1 
ATOM   1954 O  O     . GLY A 1 243 ? -15.25054 -15.32575 21.88308 1.000 24.60649  ? 240 GLY A O     1 
ATOM   1955 N  N     . PHE A 1 244 ? -14.41339 -14.37492 23.73852 1.000 21.99837  ? 241 PHE A N     1 
ATOM   1956 C  CA    . PHE A 1 244 ? -13.59779 -13.43467 22.98535 1.000 23.44224  ? 241 PHE A CA    1 
ATOM   1957 C  C     . PHE A 1 244 ? -12.31126 -13.15659 23.73839 1.000 26.05452  ? 241 PHE A C     1 
ATOM   1958 O  O     . PHE A 1 244 ? -12.20075 -13.40224 24.94059 1.000 25.89616  ? 241 PHE A O     1 
ATOM   1959 C  CB    . PHE A 1 244 ? -14.34525 -12.10940 22.71282 1.000 23.84589  ? 241 PHE A CB    1 
ATOM   1960 C  CG    . PHE A 1 244 ? -14.42879 -11.21402 23.91415 1.000 24.66822  ? 241 PHE A CG    1 
ATOM   1961 C  CD1   . PHE A 1 244 ? -15.43056 -11.38579 24.85055 1.000 26.24419  ? 241 PHE A CD1   1 
ATOM   1962 C  CD2   . PHE A 1 244 ? -13.49093 -10.21134 24.11875 1.000 28.36932  ? 241 PHE A CD2   1 
ATOM   1963 C  CE1   . PHE A 1 244 ? -15.50574 -10.56991 25.96887 1.000 31.49264  ? 241 PHE A CE1   1 
ATOM   1964 C  CE2   . PHE A 1 244 ? -13.55957 -9.39079  25.23329 1.000 28.42759  ? 241 PHE A CE2   1 
ATOM   1965 C  CZ    . PHE A 1 244 ? -14.56786 -9.57570  26.16099 1.000 29.88188  ? 241 PHE A CZ    1 
ATOM   1966 N  N     . LEU A 1 245 ? -11.33377 -12.63415 23.00548 1.000 25.11187  ? 242 LEU A N     1 
ATOM   1967 C  CA    . LEU A 1 245 ? -10.06441 -12.22018 23.58518 1.000 22.97082  ? 242 LEU A CA    1 
ATOM   1968 C  C     . LEU A 1 245 ? -9.53291  -11.05836 22.76263 1.000 26.13485  ? 242 LEU A C     1 
ATOM   1969 O  O     . LEU A 1 245 ? -10.11126 -10.68548 21.73974 1.000 23.57749  ? 242 LEU A O     1 
ATOM   1970 C  CB    . LEU A 1 245 ? -9.05699  -13.37294 23.61247 1.000 22.46256  ? 242 LEU A CB    1 
ATOM   1971 C  CG    . LEU A 1 245 ? -8.83784  -14.14973 22.30949 1.000 25.71725  ? 242 LEU A CG    1 
ATOM   1972 C  CD1   . LEU A 1 245 ? -7.83815  -13.45632 21.39845 1.000 21.80679  ? 242 LEU A CD1   1 
ATOM   1973 C  CD2   . LEU A 1 245 ? -8.35490  -15.56629 22.62885 1.000 26.49410  ? 242 LEU A CD2   1 
ATOM   1974 N  N     . ARG A 1 246 ? -8.39603  -10.51598 23.18961 1.000 20.68346  ? 243 ARG A N     1 
ATOM   1975 C  CA    . ARG A 1 246 ? -7.76952  -9.41135  22.48334 1.000 22.44951  ? 243 ARG A CA    1 
ATOM   1976 C  C     . ARG A 1 246 ? -6.25824  -9.58732  22.49413 1.000 21.34882  ? 243 ARG A C     1 
ATOM   1977 O  O     . ARG A 1 246 ? -5.71244  -10.44078 23.20260 1.000 22.39052  ? 243 ARG A O     1 
ATOM   1978 C  CB    . ARG A 1 246 ? -8.15769  -8.07252  23.10014 1.000 23.41746  ? 243 ARG A CB    1 
ATOM   1979 C  CG    . ARG A 1 246 ? -7.80662  -7.99426  24.58826 1.000 28.65040  ? 243 ARG A CG    1 
ATOM   1980 C  CD    . ARG A 1 246 ? -7.47781  -6.58425  24.98977 1.000 28.36281  ? 243 ARG A CD    1 
ATOM   1981 N  NE    . ARG A 1 246 ? -6.48845  -5.98669  24.10024 1.000 25.17271  ? 243 ARG A NE    1 
ATOM   1982 C  CZ    . ARG A 1 246 ? -6.30693  -4.67786  23.98716 1.000 30.12985  ? 243 ARG A CZ    1 
ATOM   1983 N  NH1   . ARG A 1 246 ? -7.04022  -3.82398  24.67432 1.000 31.26237  ? 243 ARG A NH1   1 
ATOM   1984 N  NH2   . ARG A 1 246 ? -5.35972  -4.21747  23.17542 1.000 28.44380  ? 243 ARG A NH2   1 
ATOM   1985 N  N     . ASN A 1 247 ? -5.58341  -8.77240  21.68386 1.000 21.10970  ? 244 ASN A N     1 
ATOM   1986 C  CA    . ASN A 1 247 ? -4.12879  -8.83352  21.60217 1.000 19.50116  ? 244 ASN A CA    1 
ATOM   1987 C  C     . ASN A 1 247 ? -3.50336  -8.42671  22.93227 1.000 20.92850  ? 244 ASN A C     1 
ATOM   1988 O  O     . ASN A 1 247 ? -4.06639  -7.63250  23.68957 1.000 19.29367  ? 244 ASN A O     1 
ATOM   1989 C  CB    . ASN A 1 247 ? -3.61065  -7.92211  20.48189 1.000 18.40189  ? 244 ASN A CB    1 
ATOM   1990 C  CG    . ASN A 1 247 ? -3.79347  -6.45159  20.79779 1.000 24.79686  ? 244 ASN A CG    1 
ATOM   1991 O  OD1   . ASN A 1 247 ? -4.91548  -5.96216  20.92504 1.000 21.80488  ? 244 ASN A OD1   1 
ATOM   1992 N  ND2   . ASN A 1 247 ? -2.68528  -5.74662  20.96734 1.000 22.01093  ? 244 ASN A ND2   1 
ATOM   1993 N  N     . GLN A 1 248 ? -2.31346  -8.96813  23.19852 1.000 19.39625  ? 245 GLN A N     1 
ATOM   1994 C  CA    . GLN A 1 248 ? -1.52446  -8.62262  24.37858 1.000 19.02279  ? 245 GLN A CA    1 
ATOM   1995 C  C     . GLN A 1 248 ? -0.43931  -7.62254  23.98637 1.000 19.28391  ? 245 GLN A C     1 
ATOM   1996 O  O     . GLN A 1 248 ? 0.44032   -7.94349  23.17989 1.000 20.53973  ? 245 GLN A O     1 
ATOM   1997 C  CB    . GLN A 1 248 ? -0.90477  -9.88212  24.98726 1.000 23.86878  ? 245 GLN A CB    1 
ATOM   1998 C  CG    . GLN A 1 248 ? -1.96363  -10.92003 25.41364 1.000 21.96298  ? 245 GLN A CG    1 
ATOM   1999 C  CD    . GLN A 1 248 ? -2.69207  -10.52353 26.70690 1.000 31.11928  ? 245 GLN A CD    1 
ATOM   2000 O  OE1   . GLN A 1 248 ? -2.11275  -9.91069  27.60488 1.000 33.60050  ? 245 GLN A OE1   1 
ATOM   2001 N  NE2   . GLN A 1 248 ? -3.97280  -10.85007 26.78350 1.000 39.05626  ? 245 GLN A NE2   1 
ATOM   2002 N  N     . ALA A 1 249 ? -0.50695  -6.41555  24.54877 1.000 18.51172  ? 246 ALA A N     1 
ATOM   2003 C  CA    . ALA A 1 249 ? 0.47312   -5.38405  24.24410 1.000 21.31895  ? 246 ALA A CA    1 
ATOM   2004 C  C     . ALA A 1 249 ? 1.83754   -5.76466  24.82000 1.000 23.10977  ? 246 ALA A C     1 
ATOM   2005 O  O     . ALA A 1 249 ? 1.91579   -6.48528  25.82148 1.000 20.70800  ? 246 ALA A O     1 
ATOM   2006 C  CB    . ALA A 1 249 ? 0.02138   -4.03561  24.81804 1.000 24.76205  ? 246 ALA A CB    1 
ATOM   2007 N  N     . PRO A 1 250 ? 2.92886   -5.27803  24.22124 1.000 21.66836  ? 247 PRO A N     1 
ATOM   2008 C  CA    . PRO A 1 250 ? 4.26249   -5.65219  24.71410 1.000 20.41512  ? 247 PRO A CA    1 
ATOM   2009 C  C     . PRO A 1 250 ? 4.50686   -5.15733  26.13233 1.000 21.85757  ? 247 PRO A C     1 
ATOM   2010 O  O     . PRO A 1 250 ? 3.99634   -4.11945  26.55407 1.000 19.30507  ? 247 PRO A O     1 
ATOM   2011 C  CB    . PRO A 1 250 ? 5.21662   -4.96404  23.72942 1.000 19.41904  ? 247 PRO A CB    1 
ATOM   2012 C  CG    . PRO A 1 250 ? 4.38472   -4.78130  22.47449 1.000 27.40023  ? 247 PRO A CG    1 
ATOM   2013 C  CD    . PRO A 1 250 ? 3.01519   -4.45381  22.99831 1.000 28.40124  ? 247 PRO A CD    1 
ATOM   2014 N  N     . ASN A 1 251 ? 5.33523   -5.90612  26.85210 1.000 16.87752  ? 248 ASN A N     1 
ATOM   2015 C  CA    . ASN A 1 251 ? 5.70244   -5.58445  28.22656 1.000 20.11028  ? 248 ASN A CA    1 
ATOM   2016 C  C     . ASN A 1 251 ? 6.80074   -6.55224  28.62034 1.000 24.83565  ? 248 ASN A C     1 
ATOM   2017 O  O     . ASN A 1 251 ? 6.66073   -7.75975  28.39825 1.000 21.67353  ? 248 ASN A O     1 
ATOM   2018 C  CB    . ASN A 1 251 ? 4.48817   -5.67710  29.16324 1.000 19.74998  ? 248 ASN A CB    1 
ATOM   2019 C  CG    . ASN A 1 251 ? 4.80770   -5.23796  30.59040 1.000 24.87132  ? 248 ASN A CG    1 
ATOM   2020 O  OD1   . ASN A 1 251 ? 5.61853   -5.86043  31.27979 1.000 22.43381  ? 248 ASN A OD1   1 
ATOM   2021 N  ND2   . ASN A 1 251 ? 4.19465   -4.13363  31.02336 1.000 22.50177  ? 248 ASN A ND2   1 
ATOM   2022 N  N     . ILE A 1 252 ? 7.90688   -6.03893  29.16711 1.000 22.06042  ? 249 ILE A N     1 
ATOM   2023 C  CA    . ILE A 1 252 ? 9.05442   -6.89554  29.43704 1.000 23.37618  ? 249 ILE A CA    1 
ATOM   2024 C  C     . ILE A 1 252 ? 8.72922   -7.95872  30.47517 1.000 26.55831  ? 249 ILE A C     1 
ATOM   2025 O  O     . ILE A 1 252 ? 9.41313   -8.98502  30.53214 1.000 27.00492  ? 249 ILE A O     1 
ATOM   2026 C  CB    . ILE A 1 252 ? 10.27998  -6.07174  29.87796 1.000 28.45039  ? 249 ILE A CB    1 
ATOM   2027 C  CG1   . ILE A 1 252 ? 10.04947  -5.45077  31.26110 1.000 31.38803  ? 249 ILE A CG1   1 
ATOM   2028 C  CG2   . ILE A 1 252 ? 10.64205  -5.02686  28.82726 1.000 34.55588  ? 249 ILE A CG2   1 
ATOM   2029 C  CD1   . ILE A 1 252 ? 11.31781  -4.90182  31.90980 1.000 34.44226  ? 249 ILE A CD1   1 
ATOM   2030 N  N     . HIS A 1 253 ? 7.69631   -7.74847  31.29697 1.000 22.31746  ? 250 HIS A N     1 
ATOM   2031 C  CA    . HIS A 1 253 ? 7.24623   -8.76517  32.24700 1.000 23.25885  ? 250 HIS A CA    1 
ATOM   2032 C  C     . HIS A 1 253 ? 6.10752   -9.62145  31.71757 1.000 27.30216  ? 250 HIS A C     1 
ATOM   2033 O  O     . HIS A 1 253 ? 5.61569   -10.49153 32.44438 1.000 28.26945  ? 250 HIS A O     1 
ATOM   2034 C  CB    . HIS A 1 253 ? 6.80851   -8.11267  33.56186 1.000 28.58793  ? 250 HIS A CB    1 
ATOM   2035 C  CG    . HIS A 1 253 ? 7.88573   -7.31742  34.22356 1.000 28.07422  ? 250 HIS A CG    1 
ATOM   2036 N  ND1   . HIS A 1 253 ? 9.14943   -7.82112  34.45005 1.000 29.85451  ? 250 HIS A ND1   1 
ATOM   2037 C  CD2   . HIS A 1 253 ? 7.89774   -6.04610  34.68497 1.000 32.64732  ? 250 HIS A CD2   1 
ATOM   2038 C  CE1   . HIS A 1 253 ? 9.88852   -6.89783  35.03692 1.000 32.74139  ? 250 HIS A CE1   1 
ATOM   2039 N  NE2   . HIS A 1 253 ? 9.15473   -5.81036  35.18547 1.000 39.05467  ? 250 HIS A NE2   1 
ATOM   2040 N  N     . GLY A 1 254 ? 5.66502   -9.38776  30.48807 1.000 23.18164  ? 251 GLY A N     1 
ATOM   2041 C  CA    . GLY A 1 254 ? 4.70684   -10.26899 29.86130 1.000 22.81966  ? 251 GLY A CA    1 
ATOM   2042 C  C     . GLY A 1 254 ? 5.34703   -10.81317 28.61053 1.000 25.89514  ? 251 GLY A C     1 
ATOM   2043 O  O     . GLY A 1 254 ? 6.33994   -11.54241 28.68256 1.000 20.58530  ? 251 GLY A O     1 
ATOM   2044 N  N     . PHE A 1 255 ? 4.81520   -10.43368 27.45732 1.000 22.93033  ? 252 PHE A N     1 
ATOM   2045 C  CA    . PHE A 1 255 ? 5.45547   -10.75077 26.19412 1.000 21.65911  ? 252 PHE A CA    1 
ATOM   2046 C  C     . PHE A 1 255 ? 6.24200   -9.54025  25.72517 1.000 23.21692  ? 252 PHE A C     1 
ATOM   2047 O  O     . PHE A 1 255 ? 5.63297   -8.50597  25.40216 1.000 24.04149  ? 252 PHE A O     1 
ATOM   2048 C  CB    . PHE A 1 255 ? 4.41219   -11.14738 25.16367 1.000 23.02175  ? 252 PHE A CB    1 
ATOM   2049 C  CG    . PHE A 1 255 ? 3.61086   -12.35296 25.57436 1.000 27.44392  ? 252 PHE A CG    1 
ATOM   2050 C  CD1   . PHE A 1 255 ? 4.10518   -13.62587 25.36900 1.000 28.62669  ? 252 PHE A CD1   1 
ATOM   2051 C  CD2   . PHE A 1 255 ? 2.37737   -12.20349 26.18305 1.000 27.79995  ? 252 PHE A CD2   1 
ATOM   2052 C  CE1   . PHE A 1 255 ? 3.37860   -14.73561 25.75858 1.000 31.95875  ? 252 PHE A CE1   1 
ATOM   2053 C  CE2   . PHE A 1 255 ? 1.65028   -13.30282 26.56376 1.000 27.46678  ? 252 PHE A CE2   1 
ATOM   2054 C  CZ    . PHE A 1 255 ? 2.15072   -14.56995 26.35132 1.000 22.43664  ? 252 PHE A CZ    1 
ATOM   2055 N  N     . PRO A 1 256 ? 7.57526   -9.60687  25.67752 1.000 24.11339  ? 253 PRO A N     1 
ATOM   2056 C  CA    . PRO A 1 256 ? 8.35671   -8.39978  25.35494 1.000 22.56072  ? 253 PRO A CA    1 
ATOM   2057 C  C     . PRO A 1 256 ? 8.01504   -7.78973  24.00630 1.000 25.42733  ? 253 PRO A C     1 
ATOM   2058 O  O     . PRO A 1 256 ? 8.16848   -6.57620  23.83548 1.000 25.40502  ? 253 PRO A O     1 
ATOM   2059 C  CB    . PRO A 1 256 ? 9.80654   -8.91085  25.39344 1.000 28.00982  ? 253 PRO A CB    1 
ATOM   2060 C  CG    . PRO A 1 256 ? 9.75533   -10.08107 26.34598 1.000 29.73176  ? 253 PRO A CG    1 
ATOM   2061 C  CD    . PRO A 1 256 ? 8.44325   -10.74857 26.03268 1.000 24.58883  ? 253 PRO A CD    1 
ATOM   2062 N  N     . LYS A 1 257 ? 7.56708   -8.58962  23.03502 1.000 23.56723  ? 254 LYS A N     1 
ATOM   2063 C  CA    . LYS A 1 257 ? 7.16538   -8.06537  21.73291 1.000 23.63381  ? 254 LYS A CA    1 
ATOM   2064 C  C     . LYS A 1 257 ? 5.66613   -8.20766  21.49665 1.000 23.65789  ? 254 LYS A C     1 
ATOM   2065 O  O     . LYS A 1 257 ? 5.20455   -8.08027  20.35859 1.000 24.81246  ? 254 LYS A O     1 
ATOM   2066 C  CB    . LYS A 1 257 ? 7.95570   -8.73670  20.60749 1.000 27.21812  ? 254 LYS A CB    1 
ATOM   2067 C  CG    . LYS A 1 257 ? 9.47344   -8.73713  20.81483 1.000 30.40004  ? 254 LYS A CG    1 
ATOM   2068 C  CD    . LYS A 1 257 ? 10.20877  -9.20462  19.55716 1.000 43.73718  ? 254 LYS A CD    1 
ATOM   2069 C  CE    . LYS A 1 257 ? 11.36395  -8.28121  19.19275 1.000 47.86962  ? 254 LYS A CE    1 
ATOM   2070 N  NZ    . LYS A 1 257 ? 12.00917  -7.70512  20.41063 1.000 54.66406  ? 254 LYS A NZ    1 
ATOM   2071 N  N     . GLY A 1 258 ? 4.89863   -8.45331  22.55350 1.000 22.44783  ? 255 GLY A N     1 
ATOM   2072 C  CA    . GLY A 1 258 ? 3.46213   -8.59202  22.44445 1.000 22.12132  ? 255 GLY A CA    1 
ATOM   2073 C  C     . GLY A 1 258 ? 3.06818   -9.98662  21.99279 1.000 21.42049  ? 255 GLY A C     1 
ATOM   2074 O  O     . GLY A 1 258 ? 3.89135   -10.80183 21.57329 1.000 20.83957  ? 255 GLY A O     1 
ATOM   2075 N  N     . ARG A 1 259 ? 1.77266   -10.27164 22.08298 1.000 23.72247  ? 256 ARG A N     1 
ATOM   2076 C  CA    . ARG A 1 259 ? 1.24372   -11.51882 21.52253 1.000 21.50422  ? 256 ARG A CA    1 
ATOM   2077 C  C     . ARG A 1 259 ? -0.07599  -11.19190 20.84050 1.000 20.24881  ? 256 ARG A C     1 
ATOM   2078 O  O     . ARG A 1 259 ? -1.05465  -10.83867 21.50842 1.000 20.36148  ? 256 ARG A O     1 
ATOM   2079 C  CB    . ARG A 1 259 ? 1.05224   -12.60119 22.58502 1.000 19.35970  ? 256 ARG A CB    1 
ATOM   2080 C  CG    . ARG A 1 259 ? 0.78929   -14.00061 21.94671 1.000 19.55217  ? 256 ARG A CG    1 
ATOM   2081 C  CD    . ARG A 1 259 ? 1.04828   -15.15285 22.90715 1.000 25.75547  ? 256 ARG A CD    1 
ATOM   2082 N  NE    . ARG A 1 259 ? 0.94875   -16.45617 22.24970 1.000 20.00842  ? 256 ARG A NE    1 
ATOM   2083 C  CZ    . ARG A 1 259 ? 1.92770   -17.00199 21.54307 1.000 30.57964  ? 256 ARG A CZ    1 
ATOM   2084 N  NH1   . ARG A 1 259 ? 3.06034   -16.35565 21.32832 1.000 31.11191  ? 256 ARG A NH1   1 
ATOM   2085 N  NH2   . ARG A 1 259 ? 1.77004   -18.23269 21.04437 1.000 26.73493  ? 256 ARG A NH2   1 
ATOM   2086 N  N     . HIS A 1 260 ? -0.10234  -11.30944 19.51986 1.000 20.17935  ? 257 HIS A N     1 
ATOM   2087 C  CA    . HIS A 1 260 ? -1.26208  -10.87005 18.75883 1.000 20.45592  ? 257 HIS A CA    1 
ATOM   2088 C  C     . HIS A 1 260 ? -2.46152  -11.77925 19.01662 1.000 23.69708  ? 257 HIS A C     1 
ATOM   2089 O  O     . HIS A 1 260 ? -2.31632  -12.94335 19.40131 1.000 18.91360  ? 257 HIS A O     1 
ATOM   2090 C  CB    . HIS A 1 260 ? -0.91689  -10.84247 17.27030 1.000 22.59245  ? 257 HIS A CB    1 
ATOM   2091 C  CG    . HIS A 1 260 ? 0.10616   -9.80554  16.90866 1.000 24.84137  ? 257 HIS A CG    1 
ATOM   2092 N  ND1   . HIS A 1 260 ? 0.35636   -9.42431  15.60808 1.000 24.36398  ? 257 HIS A ND1   1 
ATOM   2093 C  CD2   . HIS A 1 260 ? 0.92691   -9.05305  17.68284 1.000 30.16615  ? 257 HIS A CD2   1 
ATOM   2094 C  CE1   . HIS A 1 260 ? 1.29358   -8.49388  15.59108 1.000 29.22141  ? 257 HIS A CE1   1 
ATOM   2095 N  NE2   . HIS A 1 260 ? 1.65693   -8.24898  16.83872 1.000 25.22167  ? 257 HIS A NE2   1 
ATOM   2096 N  N     . ALA A 1 261 ? -3.65980  -11.23047 18.78138 1.000 18.78982  ? 258 ALA A N     1 
ATOM   2097 C  CA    . ALA A 1 261 ? -4.89828  -11.94512 19.09298 1.000 20.27826  ? 258 ALA A CA    1 
ATOM   2098 C  C     . ALA A 1 261 ? -4.96151  -13.31357 18.41919 1.000 23.57034  ? 258 ALA A C     1 
ATOM   2099 O  O     . ALA A 1 261 ? -5.34874  -14.29993 19.05343 1.000 21.64746  ? 258 ALA A O     1 
ATOM   2100 C  CB    . ALA A 1 261 ? -6.10967  -11.10517 18.67467 1.000 17.97700  ? 258 ALA A CB    1 
ATOM   2101 N  N     . ALA A 1 262 ? -4.59903  -13.39164 17.13086 1.000 20.23658  ? 259 ALA A N     1 
ATOM   2102 C  CA    . ALA A 1 262 ? -4.66255  -14.67730 16.43246 1.000 20.59445  ? 259 ALA A CA    1 
ATOM   2103 C  C     . ALA A 1 262 ? -3.79834  -15.73571 17.11591 1.000 26.87174  ? 259 ALA A C     1 
ATOM   2104 O  O     . ALA A 1 262 ? -4.19130  -16.90594 17.19916 1.000 24.79217  ? 259 ALA A O     1 
ATOM   2105 C  CB    . ALA A 1 262 ? -4.23801  -14.51571 14.96988 1.000 18.37030  ? 259 ALA A CB    1 
ATOM   2106 N  N     . LEU A 1 263 ? -2.61480  -15.35161 17.60974 1.000 22.95418  ? 260 LEU A N     1 
ATOM   2107 C  CA    . LEU A 1 263 ? -1.77331  -16.32685 18.30964 1.000 24.87395  ? 260 LEU A CA    1 
ATOM   2108 C  C     . LEU A 1 263 ? -2.39145  -16.75308 19.63649 1.000 23.46103  ? 260 LEU A C     1 
ATOM   2109 O  O     . LEU A 1 263 ? -2.32977  -17.93728 20.00368 1.000 24.42543  ? 260 LEU A O     1 
ATOM   2110 C  CB    . LEU A 1 263 ? -0.37494  -15.75690 18.54634 1.000 23.63560  ? 260 LEU A CB    1 
ATOM   2111 C  CG    . LEU A 1 263 ? 0.40790   -15.40671 17.27959 1.000 27.25150  ? 260 LEU A CG    1 
ATOM   2112 C  CD1   . LEU A 1 263 ? 1.87943   -15.22901 17.62425 1.000 28.83329  ? 260 LEU A CD1   1 
ATOM   2113 C  CD2   . LEU A 1 263 ? 0.21271   -16.47535 16.20361 1.000 27.82350  ? 260 LEU A CD2   1 
ATOM   2114 N  N     . CYS A 1 264 ? -2.97172  -15.80859 20.38506 1.000 22.56388  ? 261 CYS A N     1 
ATOM   2115 C  CA    . CYS A 1 264 ? -3.62389  -16.17821 21.64354 1.000 19.48415  ? 261 CYS A CA    1 
ATOM   2116 C  C     . CYS A 1 264 ? -4.79415  -17.10617 21.38045 1.000 25.72456  ? 261 CYS A C     1 
ATOM   2117 O  O     . CYS A 1 264 ? -5.07563  -18.01385 22.17398 1.000 24.07469  ? 261 CYS A O     1 
ATOM   2118 C  CB    . CYS A 1 264 ? -4.11847  -14.93948 22.38973 1.000 22.27813  ? 261 CYS A CB    1 
ATOM   2119 S  SG    . CYS A 1 264 ? -2.85556  -13.78565 22.91340 1.000 23.64847  ? 261 CYS A SG    1 
ATOM   2120 N  N     . PHE A 1 265 ? -5.50053  -16.87099 20.27291 1.000 20.84302  ? 262 PHE A N     1 
ATOM   2121 C  CA    . PHE A 1 265 ? -6.57169  -17.76029 19.83748 1.000 26.58916  ? 262 PHE A CA    1 
ATOM   2122 C  C     . PHE A 1 265 ? -6.03429  -19.15656 19.51886 1.000 28.71809  ? 262 PHE A C     1 
ATOM   2123 O  O     . PHE A 1 265 ? -6.57772  -20.16241 19.98786 1.000 26.15706  ? 262 PHE A O     1 
ATOM   2124 C  CB    . PHE A 1 265 ? -7.26970  -17.12229 18.62645 1.000 26.65981  ? 262 PHE A CB    1 
ATOM   2125 C  CG    . PHE A 1 265 ? -8.11248  -18.06852 17.80157 1.000 27.43193  ? 262 PHE A CG    1 
ATOM   2126 C  CD1   . PHE A 1 265 ? -9.29279  -18.59486 18.29574 1.000 32.54982  ? 262 PHE A CD1   1 
ATOM   2127 C  CD2   . PHE A 1 265 ? -7.74694  -18.37488 16.49915 1.000 31.64751  ? 262 PHE A CD2   1 
ATOM   2128 C  CE1   . PHE A 1 265 ? -10.08327 -19.44086 17.50337 1.000 30.04917  ? 262 PHE A CE1   1 
ATOM   2129 C  CE2   . PHE A 1 265 ? -8.52603  -19.21605 15.71156 1.000 38.64388  ? 262 PHE A CE2   1 
ATOM   2130 C  CZ    . PHE A 1 265 ? -9.69407  -19.75070 16.22316 1.000 32.74405  ? 262 PHE A CZ    1 
ATOM   2131 N  N     . LEU A 1 266 ? -4.94447  -19.23976 18.74342 1.000 25.35846  ? 263 LEU A N     1 
ATOM   2132 C  CA    . LEU A 1 266 ? -4.36420  -20.55429 18.43189 1.000 26.66435  ? 263 LEU A CA    1 
ATOM   2133 C  C     . LEU A 1 266 ? -3.87402  -21.28800 19.67366 1.000 27.94954  ? 263 LEU A C     1 
ATOM   2134 O  O     . LEU A 1 266 ? -3.88512  -22.53018 19.70072 1.000 26.56277  ? 263 LEU A O     1 
ATOM   2135 C  CB    . LEU A 1 266 ? -3.19805  -20.41207 17.45585 1.000 24.11920  ? 263 LEU A CB    1 
ATOM   2136 C  CG    . LEU A 1 266 ? -3.54128  -20.01595 16.02296 1.000 26.80319  ? 263 LEU A CG    1 
ATOM   2137 C  CD1   . LEU A 1 266 ? -2.25346  -19.86818 15.24268 1.000 30.05388  ? 263 LEU A CD1   1 
ATOM   2138 C  CD2   . LEU A 1 266 ? -4.43634  -21.08637 15.41084 1.000 23.91941  ? 263 LEU A CD2   1 
ATOM   2139 N  N     . ASP A 1 267 ? -3.37835  -20.54653 20.67258 1.000 25.22779  ? 264 ASP A N     1 
ATOM   2140 C  CA    . ASP A 1 267 ? -2.94197  -21.13806 21.93818 1.000 25.41094  ? 264 ASP A CA    1 
ATOM   2141 C  C     . ASP A 1 267 ? -4.06656  -21.90390 22.62200 1.000 28.42528  ? 264 ASP A C     1 
ATOM   2142 O  O     . ASP A 1 267 ? -3.81668  -22.90680 23.29719 1.000 26.61972  ? 264 ASP A O     1 
ATOM   2143 C  CB    . ASP A 1 267 ? -2.45429  -20.04181 22.90006 1.000 23.44363  ? 264 ASP A CB    1 
ATOM   2144 C  CG    . ASP A 1 267 ? -1.15817  -19.35960 22.45000 1.000 27.17695  ? 264 ASP A CG    1 
ATOM   2145 O  OD1   . ASP A 1 267 ? -0.45298  -19.87454 21.55803 1.000 27.93604  ? 264 ASP A OD1   1 
ATOM   2146 O  OD2   . ASP A 1 267 ? -0.84023  -18.28435 23.00153 1.000 24.38995  ? 264 ASP A OD2   1 
ATOM   2147 N  N     . LEU A 1 268 ? -5.30494  -21.42364 22.49925 1.000 22.22503  ? 265 LEU A N     1 
ATOM   2148 C  CA    . LEU A 1 268 ? -6.41888  -22.05420 23.20567 1.000 25.79536  ? 265 LEU A CA    1 
ATOM   2149 C  C     . LEU A 1 268 ? -6.77651  -23.41946 22.64119 1.000 27.22057  ? 265 LEU A C     1 
ATOM   2150 O  O     . LEU A 1 268 ? -7.21833  -24.29821 23.39513 1.000 26.50652  ? 265 LEU A O     1 
ATOM   2151 C  CB    . LEU A 1 268 ? -7.66302  -21.17600 23.13384 1.000 23.80004  ? 265 LEU A CB    1 
ATOM   2152 C  CG    . LEU A 1 268 ? -7.64421  -19.84467 23.85959 1.000 29.32545  ? 265 LEU A CG    1 
ATOM   2153 C  CD1   . LEU A 1 268 ? -8.95789  -19.14827 23.58598 1.000 29.04696  ? 265 LEU A CD1   1 
ATOM   2154 C  CD2   . LEU A 1 268 ? -7.45232  -20.07961 25.32273 1.000 29.53263  ? 265 LEU A CD2   1 
ATOM   2155 N  N     . ILE A 1 269 ? -6.64270  -23.60343 21.32242 1.000 28.99184  ? 266 ILE A N     1 
ATOM   2156 C  CA    . ILE A 1 269 ? -7.23001  -24.78098 20.67901 1.000 31.73926  ? 266 ILE A CA    1 
ATOM   2157 C  C     . ILE A 1 269 ? -6.66397  -26.08936 21.22653 1.000 32.41867  ? 266 ILE A C     1 
ATOM   2158 O  O     . ILE A 1 269 ? -7.45785  -26.98458 21.55180 1.000 31.48004  ? 266 ILE A O     1 
ATOM   2159 C  CB    . ILE A 1 269 ? -7.11072  -24.67127 19.14792 1.000 25.46409  ? 266 ILE A CB    1 
ATOM   2160 C  CG1   . ILE A 1 269 ? -7.74971  -23.36785 18.64890 1.000 30.04052  ? 266 ILE A CG1   1 
ATOM   2161 C  CG2   . ILE A 1 269 ? -7.77653  -25.88021 18.45650 1.000 28.50912  ? 266 ILE A CG2   1 
ATOM   2162 C  CD1   . ILE A 1 269 ? -7.64699  -23.20383 17.14011 1.000 27.44380  ? 266 ILE A CD1   1 
ATOM   2163 N  N     . PRO A 1 270 ? -5.33877  -26.27633 21.34357 1.000 33.50833  ? 267 PRO A N     1 
ATOM   2164 C  CA    . PRO A 1 270 ? -4.84486  -27.53506 21.93415 1.000 34.39096  ? 267 PRO A CA    1 
ATOM   2165 C  C     . PRO A 1 270 ? -5.28301  -27.70305 23.36728 1.000 30.33480  ? 267 PRO A C     1 
ATOM   2166 O  O     . PRO A 1 270 ? -5.44391  -28.82996 23.85392 1.000 27.28033  ? 267 PRO A O     1 
ATOM   2167 C  CB    . PRO A 1 270 ? -3.31864  -27.39266 21.83495 1.000 41.86947  ? 267 PRO A CB    1 
ATOM   2168 C  CG    . PRO A 1 270 ? -3.10033  -26.38958 20.76276 1.000 45.39133  ? 267 PRO A CG    1 
ATOM   2169 C  CD    . PRO A 1 270 ? -4.21804  -25.42080 20.91651 1.000 37.18903  ? 267 PRO A CD    1 
ATOM   2170 N  N     . PHE A 1 271 ? -5.48170  -26.58762 24.05591 1.000 29.18879  ? 268 PHE A N     1 
ATOM   2171 C  CA    . PHE A 1 271 ? -5.84586  -26.58806 25.45856 1.000 28.90922  ? 268 PHE A CA    1 
ATOM   2172 C  C     . PHE A 1 271 ? -7.28519  -27.04770 25.65590 1.000 33.98705  ? 268 PHE A C     1 
ATOM   2173 O  O     . PHE A 1 271 ? -7.62774  -27.52922 26.74183 1.000 27.18947  ? 268 PHE A O     1 
ATOM   2174 C  CB    . PHE A 1 271 ? -5.58089  -25.17490 25.98433 1.000 29.73616  ? 268 PHE A CB    1 
ATOM   2175 C  CG    . PHE A 1 271 ? -5.55694  -25.04757 27.47054 1.000 28.46896  ? 268 PHE A CG    1 
ATOM   2176 C  CD1   . PHE A 1 271 ? -4.59032  -25.69771 28.21720 1.000 27.79676  ? 268 PHE A CD1   1 
ATOM   2177 C  CD2   . PHE A 1 271 ? -6.44743  -24.20058 28.11077 1.000 27.08340  ? 268 PHE A CD2   1 
ATOM   2178 C  CE1   . PHE A 1 271 ? -4.55017  -25.55545 29.58531 1.000 34.38481  ? 268 PHE A CE1   1 
ATOM   2179 C  CE2   . PHE A 1 271 ? -6.40800  -24.03728 29.48546 1.000 28.48445  ? 268 PHE A CE2   1 
ATOM   2180 C  CZ    . PHE A 1 271 ? -5.45269  -24.70912 30.22409 1.000 34.16615  ? 268 PHE A CZ    1 
ATOM   2181 N  N     . TRP A 1 272 ? -8.11864  -26.95374 24.61077 1.000 26.94880  ? 269 TRP A N     1 
ATOM   2182 C  CA    . TRP A 1 272 ? -9.47777  -27.48201 24.66756 1.000 30.32326  ? 269 TRP A CA    1 
ATOM   2183 C  C     . TRP A 1 272 ? -9.51474  -29.00259 24.67122 1.000 29.93747  ? 269 TRP A C     1 
ATOM   2184 O  O     . TRP A 1 272 ? -10.53546 -29.57934 25.05853 1.000 33.50729  ? 269 TRP A O     1 
ATOM   2185 C  CB    . TRP A 1 272 ? -10.29863 -27.00722 23.46596 1.000 30.91147  ? 269 TRP A CB    1 
ATOM   2186 C  CG    . TRP A 1 272 ? -10.57132 -25.54201 23.42221 1.000 28.28741  ? 269 TRP A CG    1 
ATOM   2187 C  CD1   . TRP A 1 272 ? -10.56289 -24.66214 24.47134 1.000 36.81385  ? 269 TRP A CD1   1 
ATOM   2188 C  CD2   . TRP A 1 272 ? -10.89723 -24.78172 22.25737 1.000 29.85397  ? 269 TRP A CD2   1 
ATOM   2189 N  NE1   . TRP A 1 272 ? -10.86811 -23.39471 24.02162 1.000 30.55867  ? 269 TRP A NE1   1 
ATOM   2190 C  CE2   . TRP A 1 272 ? -11.07783 -23.44681 22.66535 1.000 26.71092  ? 269 TRP A CE2   1 
ATOM   2191 C  CE3   . TRP A 1 272 ? -11.06078 -25.10554 20.90452 1.000 30.82778  ? 269 TRP A CE3   1 
ATOM   2192 C  CZ2   . TRP A 1 272 ? -11.40555 -22.43298 21.76814 1.000 29.67214  ? 269 TRP A CZ2   1 
ATOM   2193 C  CZ3   . TRP A 1 272 ? -11.38275 -24.09558 20.01266 1.000 31.81025  ? 269 TRP A CZ3   1 
ATOM   2194 C  CH2   . TRP A 1 272 ? -11.55044 -22.77306 20.45140 1.000 30.37447  ? 269 TRP A CH2   1 
ATOM   2195 N  N     . LYS A 1 273 ? -8.46194  -29.65253 24.17904 1.000 29.82739  ? 270 LYS A N     1 
ATOM   2196 C  CA    . LYS A 1 273 ? -8.38075  -31.11345 24.11965 1.000 34.05823  ? 270 LYS A CA    1 
ATOM   2197 C  C     . LYS A 1 273 ? -9.52954  -31.70015 23.29865 1.000 40.68268  ? 270 LYS A C     1 
ATOM   2198 O  O     . LYS A 1 273 ? -10.24284 -32.60716 23.73504 1.000 35.59638  ? 270 LYS A O     1 
ATOM   2199 C  CB    . LYS A 1 273 ? -8.34091  -31.70625 25.52902 1.000 37.53459  ? 270 LYS A CB    1 
ATOM   2200 C  CG    . LYS A 1 273 ? -7.00966  -31.51724 26.21010 1.000 32.61325  ? 270 LYS A CG    1 
ATOM   2201 C  CD    . LYS A 1 273 ? -5.91601  -32.27711 25.48664 1.000 39.75904  ? 270 LYS A CD    1 
ATOM   2202 C  CE    . LYS A 1 273 ? -4.56197  -32.08186 26.15759 1.000 46.73638  ? 270 LYS A CE    1 
ATOM   2203 N  NZ    . LYS A 1 273 ? -3.53196  -32.97333 25.55990 1.000 44.43579  ? 270 LYS A NZ    1 
ATOM   2204 N  N     . LEU A 1 274 ? -9.71034  -31.16403 22.09356 1.000 36.26165  ? 271 LEU A N     1 
ATOM   2205 C  CA    . LEU A 1 274 ? -10.73013 -31.68562 21.19839 1.000 44.61568  ? 271 LEU A CA    1 
ATOM   2206 C  C     . LEU A 1 274 ? -10.40985 -33.13860 20.86572 1.000 46.39406  ? 271 LEU A C     1 
ATOM   2207 O  O     . LEU A 1 274 ? -9.24117  -33.51473 20.74420 1.000 47.67865  ? 271 LEU A O     1 
ATOM   2208 C  CB    . LEU A 1 274 ? -10.78255 -30.84422 19.92266 1.000 41.07158  ? 271 LEU A CB    1 
ATOM   2209 C  CG    . LEU A 1 274 ? -11.27886 -29.40568 20.10477 1.000 35.91889  ? 271 LEU A CG    1 
ATOM   2210 C  CD1   . LEU A 1 274 ? -11.29124 -28.66757 18.77102 1.000 39.28795  ? 271 LEU A CD1   1 
ATOM   2211 C  CD2   . LEU A 1 274 ? -12.63652 -29.34717 20.78844 1.000 37.49870  ? 271 LEU A CD2   1 
ATOM   2212 N  N     . ASP A 1 275 ? -11.44619 -33.96328 20.73190 1.000 46.21134  ? 272 ASP A N     1 
ATOM   2213 C  CA    . ASP A 1 275 ? -11.22957 -35.36125 20.37626 1.000 54.35998  ? 272 ASP A CA    1 
ATOM   2214 C  C     . ASP A 1 275 ? -10.99899 -35.47576 18.86823 1.000 53.32054  ? 272 ASP A C     1 
ATOM   2215 O  O     . ASP A 1 275 ? -10.74092 -34.48791 18.17438 1.000 52.62613  ? 272 ASP A O     1 
ATOM   2216 C  CB    . ASP A 1 275 ? -12.38278 -36.23833 20.87297 1.000 57.01753  ? 272 ASP A CB    1 
ATOM   2217 C  CG    . ASP A 1 275 ? -13.70681 -35.95844 20.16912 1.000 54.45865  ? 272 ASP A CG    1 
ATOM   2218 O  OD1   . ASP A 1 275 ? -13.73696 -35.21896 19.16656 1.000 49.35328  ? 272 ASP A OD1   1 
ATOM   2219 O  OD2   . ASP A 1 275 ? -14.73368 -36.50828 20.62646 1.000 56.00002  ? 272 ASP A OD2   1 
ATOM   2220 N  N     . GLY A 1 276 ? -11.09586 -36.69664 18.34437 1.000 44.23704  ? 273 GLY A N     1 
ATOM   2221 C  CA    . GLY A 1 276 ? -10.83052 -36.99194 16.95353 1.000 46.61085  ? 273 GLY A CA    1 
ATOM   2222 C  C     . GLY A 1 276 ? -11.90955 -36.61186 15.96438 1.000 49.77114  ? 273 GLY A C     1 
ATOM   2223 O  O     . GLY A 1 276 ? -11.69207 -36.73734 14.75546 1.000 49.76468  ? 273 GLY A O     1 
ATOM   2224 N  N     . GLN A 1 277 ? -13.06397 -36.14376 16.43135 1.000 45.27945  ? 274 GLN A N     1 
ATOM   2225 C  CA    . GLN A 1 277 ? -14.14220 -35.78466 15.52379 1.000 42.01248  ? 274 GLN A CA    1 
ATOM   2226 C  C     . GLN A 1 277 ? -13.76409 -34.54030 14.71913 1.000 47.78956  ? 274 GLN A C     1 
ATOM   2227 O  O     . GLN A 1 277 ? -12.78095 -33.85322 15.00914 1.000 45.90175  ? 274 GLN A O     1 
ATOM   2228 C  CB    . GLN A 1 277 ? -15.42861 -35.54012 16.30792 1.000 49.96235  ? 274 GLN A CB    1 
ATOM   2229 C  CG    . GLN A 1 277 ? -15.84221 -36.71765 17.17713 1.000 54.81375  ? 274 GLN A CG    1 
ATOM   2230 C  CD    . GLN A 1 277 ? -17.19185 -36.51090 17.81319 1.000 54.33778  ? 274 GLN A CD    1 
ATOM   2231 O  OE1   . GLN A 1 277 ? -18.20989 -36.45920 17.12799 1.000 59.18861  ? 274 GLN A OE1   1 
ATOM   2232 N  NE2   . GLN A 1 277 ? -17.20751 -36.36537 19.13402 1.000 60.98723  ? 274 GLN A NE2   1 
ATOM   2233 N  N     . GLN A 1 278 ? -14.56098 -34.24711 13.69701 1.000 39.92520  ? 275 GLN A N     1 
ATOM   2234 C  CA    . GLN A 1 278 ? -14.31043 -33.07555 12.86871 1.000 41.39796  ? 275 GLN A CA    1 
ATOM   2235 C  C     . GLN A 1 278 ? -14.88375 -31.83332 13.53199 1.000 38.84478  ? 275 GLN A C     1 
ATOM   2236 O  O     . GLN A 1 278 ? -16.00576 -31.84948 14.04456 1.000 42.88738  ? 275 GLN A O     1 
ATOM   2237 C  CB    . GLN A 1 278 ? -14.92721 -33.25564 11.48021 1.000 52.71045  ? 275 GLN A CB    1 
ATOM   2238 C  CG    . GLN A 1 278 ? -14.14171 -34.18518 10.57318 1.000 59.34257  ? 275 GLN A CG    1 
ATOM   2239 C  CD    . GLN A 1 278 ? -12.80772 -33.59643 10.15371 1.000 66.50928  ? 275 GLN A CD    1 
ATOM   2240 O  OE1   . GLN A 1 278 ? -11.75792 -34.21210 10.34754 1.000 71.82449  ? 275 GLN A OE1   1 
ATOM   2241 N  NE2   . GLN A 1 278 ? -12.84074 -32.39284 9.58613  1.000 62.10229  ? 275 GLN A NE2   1 
ATOM   2242 N  N     . TYR A 1 279 ? -14.10917 -30.74841 13.51669 1.000 39.40921  ? 276 TYR A N     1 
ATOM   2243 C  CA    . TYR A 1 279 ? -14.48520 -29.51694 14.19395 1.000 35.19140  ? 276 TYR A CA    1 
ATOM   2244 C  C     . TYR A 1 279 ? -14.27359 -28.33974 13.25438 1.000 41.54524  ? 276 TYR A C     1 
ATOM   2245 O  O     . TYR A 1 279 ? -13.29615 -28.30192 12.50053 1.000 40.19135  ? 276 TYR A O     1 
ATOM   2246 C  CB    . TYR A 1 279 ? -13.68044 -29.32066 15.49470 1.000 38.19413  ? 276 TYR A CB    1 
ATOM   2247 C  CG    . TYR A 1 279 ? -14.11345 -30.27173 16.58559 1.000 41.66630  ? 276 TYR A CG    1 
ATOM   2248 C  CD1   . TYR A 1 279 ? -15.26474 -30.03168 17.32819 1.000 36.65878  ? 276 TYR A CD1   1 
ATOM   2249 C  CD2   . TYR A 1 279 ? -13.40905 -31.44033 16.83103 1.000 41.21571  ? 276 TYR A CD2   1 
ATOM   2250 C  CE1   . TYR A 1 279 ? -15.68385 -30.91882 18.30986 1.000 41.75793  ? 276 TYR A CE1   1 
ATOM   2251 C  CE2   . TYR A 1 279 ? -13.82262 -32.33620 17.80709 1.000 40.13786  ? 276 TYR A CE2   1 
ATOM   2252 C  CZ    . TYR A 1 279 ? -14.95843 -32.06834 18.54421 1.000 50.78684  ? 276 TYR A CZ    1 
ATOM   2253 O  OH    . TYR A 1 279 ? -15.36977 -32.95774 19.51748 1.000 49.23921  ? 276 TYR A OH    1 
ATOM   2254 N  N     . ARG A 1 280 ? -15.22169 -27.41050 13.26844 1.000 37.84071  ? 277 ARG A N     1 
ATOM   2255 C  CA    . ARG A 1 280 ? -15.09410 -26.13461 12.57231 1.000 41.76304  ? 277 ARG A CA    1 
ATOM   2256 C  C     . ARG A 1 280 ? -14.95429 -25.04039 13.61894 1.000 37.42108  ? 277 ARG A C     1 
ATOM   2257 O  O     . ARG A 1 280 ? -15.86758 -24.82570 14.42212 1.000 33.79468  ? 277 ARG A O     1 
ATOM   2258 C  CB    . ARG A 1 280 ? -16.29278 -25.85508 11.66539 1.000 35.65826  ? 277 ARG A CB    1 
ATOM   2259 C  CG    . ARG A 1 280 ? -16.17073 -24.52665 10.88215 1.000 39.63656  ? 277 ARG A CG    1 
ATOM   2260 C  CD    . ARG A 1 280 ? -17.20480 -24.42823 9.77819  1.000 45.77491  ? 277 ARG A CD    1 
ATOM   2261 N  NE    . ARG A 1 280 ? -18.54893 -24.30672 10.32939 1.000 45.98988  ? 277 ARG A NE    1 
ATOM   2262 C  CZ    . ARG A 1 280 ? -19.66027 -24.33043 9.60537  1.000 53.07273  ? 277 ARG A CZ    1 
ATOM   2263 N  NH1   . ARG A 1 280 ? -19.62523 -24.47363 8.29154  1.000 43.64262  ? 277 ARG A NH1   1 
ATOM   2264 N  NH2   . ARG A 1 280 ? -20.83762 -24.22225 10.21746 1.000 56.40368  ? 277 ARG A NH2   1 
ATOM   2265 N  N     . VAL A 1 281 ? -13.80833 -24.36833 13.61819 1.000 34.01532  ? 278 VAL A N     1 
ATOM   2266 C  CA    . VAL A 1 281 ? -13.50457 -23.30143 14.56345 1.000 31.34838  ? 278 VAL A CA    1 
ATOM   2267 C  C     . VAL A 1 281 ? -13.57947 -21.98969 13.79600 1.000 34.58533  ? 278 VAL A C     1 
ATOM   2268 O  O     . VAL A 1 281 ? -12.86235 -21.81211 12.80532 1.000 31.76110  ? 278 VAL A O     1 
ATOM   2269 C  CB    . VAL A 1 281 ? -12.12156 -23.48374 15.20096 1.000 28.69844  ? 278 VAL A CB    1 
ATOM   2270 C  CG1   . VAL A 1 281 ? -11.89785 -22.43955 16.27284 1.000 28.19266  ? 278 VAL A CG1   1 
ATOM   2271 C  CG2   . VAL A 1 281 ? -11.98479 -24.89104 15.79026 1.000 28.82114  ? 278 VAL A CG2   1 
ATOM   2272 N  N     . THR A 1 282 ? -14.44518 -21.08360 14.24551 1.000 30.40026  ? 279 THR A N     1 
ATOM   2273 C  CA    . THR A 1 282 ? -14.68038 -19.81498 13.56815 1.000 27.18560  ? 279 THR A CA    1 
ATOM   2274 C  C     . THR A 1 282 ? -14.22533 -18.67691 14.46748 1.000 28.71231  ? 279 THR A C     1 
ATOM   2275 O  O     . THR A 1 282 ? -14.50378 -18.66896 15.66937 1.000 27.41890  ? 279 THR A O     1 
ATOM   2276 C  CB    . THR A 1 282 ? -16.16369 -19.63306 13.20818 1.000 30.26582  ? 279 THR A CB    1 
ATOM   2277 O  OG1   . THR A 1 282 ? -16.58813 -20.72329 12.39288 1.000 32.46145  ? 279 THR A OG1   1 
ATOM   2278 C  CG2   . THR A 1 282 ? -16.38354 -18.32655 12.40522 1.000 27.55173  ? 279 THR A CG2   1 
ATOM   2279 N  N     . CYS A 1 283 ? -13.52374 -17.71480 13.88665 1.000 28.13474  ? 280 CYS A N     1 
ATOM   2280 C  CA    . CYS A 1 283 ? -13.13235 -16.51770 14.61101 1.000 22.86087  ? 280 CYS A CA    1 
ATOM   2281 C  C     . CYS A 1 283 ? -13.57925 -15.27799 13.84386 1.000 28.86957  ? 280 CYS A C     1 
ATOM   2282 O  O     . CYS A 1 283 ? -13.54800 -15.24983 12.61458 1.000 27.02140  ? 280 CYS A O     1 
ATOM   2283 C  CB    . CYS A 1 283 ? -11.62339 -16.53919 14.89530 1.000 30.64656  ? 280 CYS A CB    1 
ATOM   2284 S  SG    . CYS A 1 283 ? -10.57163 -16.18279 13.49600 1.000 34.47058  ? 280 CYS A SG    1 
ATOM   2285 N  N     . PHE A 1 284 ? -14.06061 -14.28617 14.58855 1.000 27.61074  ? 281 PHE A N     1 
ATOM   2286 C  CA    . PHE A 1 284 ? -14.50050 -12.99721 14.05788 1.000 27.73535  ? 281 PHE A CA    1 
ATOM   2287 C  C     . PHE A 1 284 ? -13.53591 -11.97085 14.62291 1.000 23.14364  ? 281 PHE A C     1 
ATOM   2288 O  O     . PHE A 1 284 ? -13.59375 -11.64746 15.81028 1.000 26.61574  ? 281 PHE A O     1 
ATOM   2289 C  CB    . PHE A 1 284 ? -15.93081 -12.68248 14.47308 1.000 26.87312  ? 281 PHE A CB    1 
ATOM   2290 C  CG    . PHE A 1 284 ? -16.91087 -13.75698 14.12985 1.000 28.11405  ? 281 PHE A CG    1 
ATOM   2291 C  CD1   . PHE A 1 284 ? -17.13663 -14.81285 15.00117 1.000 29.83690  ? 281 PHE A CD1   1 
ATOM   2292 C  CD2   . PHE A 1 284 ? -17.63380 -13.69848 12.94951 1.000 24.23423  ? 281 PHE A CD2   1 
ATOM   2293 C  CE1   . PHE A 1 284 ? -18.04123 -15.80102 14.69027 1.000 29.78474  ? 281 PHE A CE1   1 
ATOM   2294 C  CE2   . PHE A 1 284 ? -18.54752 -14.67697 12.62970 1.000 30.52527  ? 281 PHE A CE2   1 
ATOM   2295 C  CZ    . PHE A 1 284 ? -18.75044 -15.74069 13.50460 1.000 30.07705  ? 281 PHE A CZ    1 
ATOM   2296 N  N     . THR A 1 285 ? -12.63783 -11.47216 13.78773 1.000 23.50826  ? 282 THR A N     1 
ATOM   2297 C  CA    . THR A 1 285 ? -11.51496 -10.69275 14.27230 1.000 22.19869  ? 282 THR A CA    1 
ATOM   2298 C  C     . THR A 1 285 ? -11.58764 -9.28757  13.68070 1.000 23.38428  ? 282 THR A C     1 
ATOM   2299 O  O     . THR A 1 285 ? -11.88618 -9.11647  12.49539 1.000 22.73412  ? 282 THR A O     1 
ATOM   2300 C  CB    . THR A 1 285 ? -10.19252 -11.41903 13.93062 1.000 22.61053  ? 282 THR A CB    1 
ATOM   2301 O  OG1   . THR A 1 285 ? -9.06804  -10.70054 14.46916 1.000 26.18881  ? 282 THR A OG1   1 
ATOM   2302 C  CG2   . THR A 1 285 ? -10.02419 -11.61999 12.41766 1.000 24.32847  ? 282 THR A CG2   1 
ATOM   2303 N  N     . SER A 1 286 ? -11.34502 -8.27053  14.51615 1.000 20.39470  ? 283 SER A N     1 
ATOM   2304 C  CA    . SER A 1 286 ? -11.57065 -6.90166  14.05255 1.000 19.49499  ? 283 SER A CA    1 
ATOM   2305 C  C     . SER A 1 286 ? -10.56014 -6.49892  12.98169 1.000 21.41194  ? 283 SER A C     1 
ATOM   2306 O  O     . SER A 1 286 ? -10.89020 -5.70917  12.08421 1.000 26.35246  ? 283 SER A O     1 
ATOM   2307 C  CB    . SER A 1 286 ? -11.56716 -5.92629  15.24367 1.000 22.04766  ? 283 SER A CB    1 
ATOM   2308 O  OG    . SER A 1 286 ? -10.34156 -5.91749  15.96835 1.000 19.98279  ? 283 SER A OG    1 
ATOM   2309 N  N     . TRP A 1 287 ? -9.34248  -7.03786  13.04145 1.000 23.00826  ? 284 TRP A N     1 
ATOM   2310 C  CA    . TRP A 1 287 ? -8.34022  -6.88142  11.99477 1.000 21.81556  ? 284 TRP A CA    1 
ATOM   2311 C  C     . TRP A 1 287 ? -7.99322  -8.25478  11.42941 1.000 20.66043  ? 284 TRP A C     1 
ATOM   2312 O  O     . TRP A 1 287 ? -7.79457  -9.19871  12.19169 1.000 23.15292  ? 284 TRP A O     1 
ATOM   2313 C  CB    . TRP A 1 287 ? -7.05302  -6.26800  12.53146 1.000 20.74282  ? 284 TRP A CB    1 
ATOM   2314 C  CG    . TRP A 1 287 ? -7.08284  -4.79163  12.84898 1.000 20.78902  ? 284 TRP A CG    1 
ATOM   2315 C  CD1   . TRP A 1 287 ? -6.97247  -4.23370  14.10060 1.000 22.70198  ? 284 TRP A CD1   1 
ATOM   2316 C  CD2   . TRP A 1 287 ? -7.16614  -3.70591  11.92756 1.000 22.37118  ? 284 TRP A CD2   1 
ATOM   2317 N  NE1   . TRP A 1 287 ? -7.00720  -2.86149  14.00975 1.000 18.93639  ? 284 TRP A NE1   1 
ATOM   2318 C  CE2   . TRP A 1 287 ? -7.11765  -2.50958  12.68809 1.000 23.51205  ? 284 TRP A CE2   1 
ATOM   2319 C  CE3   . TRP A 1 287 ? -7.28491  -3.61767  10.53026 1.000 20.89402  ? 284 TRP A CE3   1 
ATOM   2320 C  CZ2   . TRP A 1 287 ? -7.19422  -1.24625  12.10106 1.000 24.42342  ? 284 TRP A CZ2   1 
ATOM   2321 C  CZ3   . TRP A 1 287 ? -7.34493  -2.35743  9.94638  1.000 19.83711  ? 284 TRP A CZ3   1 
ATOM   2322 C  CH2   . TRP A 1 287 ? -7.30116  -1.18774  10.73641 1.000 24.68514  ? 284 TRP A CH2   1 
ATOM   2323 N  N     . SER A 1 288 ? -7.87165  -8.35247  10.10411 1.000 26.11152  ? 285 SER A N     1 
ATOM   2324 C  CA    . SER A 1 288 ? -7.33347  -9.56568  9.50720  1.000 22.87181  ? 285 SER A CA    1 
ATOM   2325 C  C     . SER A 1 288 ? -5.90937  -9.79309  10.02073 1.000 24.98520  ? 285 SER A C     1 
ATOM   2326 O  O     . SER A 1 288 ? -5.21977  -8.84057  10.39711 1.000 22.79170  ? 285 SER A O     1 
ATOM   2327 C  CB    . SER A 1 288 ? -7.34079  -9.46887  7.97998  1.000 25.37156  ? 285 SER A CB    1 
ATOM   2328 O  OG    . SER A 1 288 ? -6.50206  -8.42968  7.49256  1.000 26.57755  ? 285 SER A OG    1 
ATOM   2329 N  N     . PRO A 1 289 ? -5.44452  -11.04099 10.07178 1.000 25.74587  ? 286 PRO A N     1 
ATOM   2330 C  CA    . PRO A 1 289 ? -4.12120  -11.29469 10.66074 1.000 23.16676  ? 286 PRO A CA    1 
ATOM   2331 C  C     . PRO A 1 289 ? -2.99321  -10.74543 9.79399  1.000 24.74294  ? 286 PRO A C     1 
ATOM   2332 O  O     . PRO A 1 289 ? -3.03930  -10.80320 8.55985  1.000 26.11564  ? 286 PRO A O     1 
ATOM   2333 C  CB    . PRO A 1 289 ? -4.06071  -12.82419 10.75668 1.000 26.70030  ? 286 PRO A CB    1 
ATOM   2334 C  CG    . PRO A 1 289 ? -5.01154  -13.29793 9.70864  1.000 26.23318  ? 286 PRO A CG    1 
ATOM   2335 C  CD    . PRO A 1 289 ? -6.13649  -12.29501 9.71897  1.000 22.49743  ? 286 PRO A CD    1 
ATOM   2336 N  N     . CYS A 1 290 ? -1.97189  -10.21562 10.46643 1.000 25.89030  ? 287 CYS A N     1 
ATOM   2337 C  CA    . CYS A 1 290 ? -0.71703  -9.84153  9.83466  1.000 27.98893  ? 287 CYS A CA    1 
ATOM   2338 C  C     . CYS A 1 290 ? -0.01155  -11.08817 9.30323  1.000 29.01387  ? 287 CYS A C     1 
ATOM   2339 O  O     . CYS A 1 290 ? -0.43658  -12.22519 9.53438  1.000 26.55402  ? 287 CYS A O     1 
ATOM   2340 C  CB    . CYS A 1 290 ? 0.19127   -9.10730  10.82890 1.000 26.08137  ? 287 CYS A CB    1 
ATOM   2341 S  SG    . CYS A 1 290 ? 0.94486   -10.19986 12.10669 1.000 26.33675  ? 287 CYS A SG    1 
ATOM   2342 N  N     . PHE A 1 291 ? 1.09284   -10.86938 8.58758  1.000 34.84246  ? 288 PHE A N     1 
ATOM   2343 C  CA    . PHE A 1 291 ? 1.78053   -11.99702 7.96319  1.000 36.76001  ? 288 PHE A CA    1 
ATOM   2344 C  C     . PHE A 1 291 ? 2.20651   -13.03495 8.99931  1.000 34.92833  ? 288 PHE A C     1 
ATOM   2345 O  O     . PHE A 1 291 ? 2.02359   -14.24276 8.79541  1.000 31.22526  ? 288 PHE A O     1 
ATOM   2346 C  CB    . PHE A 1 291 ? 2.99418   -11.51676 7.16500  1.000 34.17265  ? 288 PHE A CB    1 
ATOM   2347 C  CG    . PHE A 1 291 ? 3.76813   -12.64686 6.53266  1.000 41.19969  ? 288 PHE A CG    1 
ATOM   2348 C  CD1   . PHE A 1 291 ? 3.17687   -13.44695 5.56334  1.000 39.98881  ? 288 PHE A CD1   1 
ATOM   2349 C  CD2   . PHE A 1 291 ? 5.05659   -12.94630 6.94571  1.000 47.84418  ? 288 PHE A CD2   1 
ATOM   2350 C  CE1   . PHE A 1 291 ? 3.87046   -14.50703 4.99158  1.000 48.90731  ? 288 PHE A CE1   1 
ATOM   2351 C  CE2   . PHE A 1 291 ? 5.76112   -14.01336 6.37638  1.000 49.85209  ? 288 PHE A CE2   1 
ATOM   2352 C  CZ    . PHE A 1 291 ? 5.16270   -14.78980 5.39929  1.000 49.67685  ? 288 PHE A CZ    1 
ATOM   2353 N  N     . SER A 1 292 ? 2.76988   -12.59015 10.12528 1.000 32.14416  ? 289 SER A N     1 
ATOM   2354 C  CA    . SER A 1 292 ? 3.27741   -13.55883 11.09056 1.000 38.40833  ? 289 SER A CA    1 
ATOM   2355 C  C     . SER A 1 292 ? 2.14077   -14.34389 11.74492 1.000 32.67541  ? 289 SER A C     1 
ATOM   2356 O  O     . SER A 1 292 ? 2.29476   -15.54057 12.01509 1.000 31.22569  ? 289 SER A O     1 
ATOM   2357 C  CB    . SER A 1 292 ? 4.14856   -12.85619 12.13895 1.000 37.93534  ? 289 SER A CB    1 
ATOM   2358 O  OG    . SER A 1 292 ? 3.37028   -12.22189 13.13490 1.000 50.19214  ? 289 SER A OG    1 
ATOM   2359 N  N     . CYS A 1 293 ? 0.98869   -13.70277 11.97960 1.000 29.79468  ? 290 CYS A N     1 
ATOM   2360 C  CA    . CYS A 1 293 ? -0.17359  -14.42505 12.49642 1.000 27.41533  ? 290 CYS A CA    1 
ATOM   2361 C  C     . CYS A 1 293 ? -0.68414  -15.45208 11.49201 1.000 30.65147  ? 290 CYS A C     1 
ATOM   2362 O  O     . CYS A 1 293 ? -0.94856  -16.60406 11.85136 1.000 31.32941  ? 290 CYS A O     1 
ATOM   2363 C  CB    . CYS A 1 293 ? -1.29049  -13.44849 12.85797 1.000 25.67128  ? 290 CYS A CB    1 
ATOM   2364 S  SG    . CYS A 1 293 ? -1.02512  -12.56867 14.40126 1.000 23.42765  ? 290 CYS A SG    1 
ATOM   2365 N  N     . ALA A 1 294 ? -0.85508  -15.04349 10.23229 1.000 27.83464  ? 291 ALA A N     1 
ATOM   2366 C  CA    . ALA A 1 294 ? -1.41845  -15.94161 9.22656  1.000 29.09678  ? 291 ALA A CA    1 
ATOM   2367 C  C     . ALA A 1 294 ? -0.49061  -17.11438 8.94696  1.000 34.66264  ? 291 ALA A C     1 
ATOM   2368 O  O     . ALA A 1 294 ? -0.95344  -18.21302 8.61413  1.000 32.79336  ? 291 ALA A O     1 
ATOM   2369 C  CB    . ALA A 1 294 ? -1.71081  -15.16721 7.93970  1.000 34.49350  ? 291 ALA A CB    1 
ATOM   2370 N  N     . GLN A 1 295 ? 0.81521   -16.89862 9.09231  1.000 31.15397  ? 292 GLN A N     1 
ATOM   2371 C  CA    . GLN A 1 295 ? 1.78512   -17.97519 8.94191  1.000 37.70263  ? 292 GLN A CA    1 
ATOM   2372 C  C     . GLN A 1 295 ? 1.60502   -19.01562 10.04226 1.000 39.35478  ? 292 GLN A C     1 
ATOM   2373 O  O     . GLN A 1 295 ? 1.59024   -20.22590 9.78603  1.000 36.64235  ? 292 GLN A O     1 
ATOM   2374 C  CB    . GLN A 1 295 ? 3.18994   -17.37359 8.98076  1.000 39.52794  ? 292 GLN A CB    1 
ATOM   2375 C  CG    . GLN A 1 295 ? 3.96470   -17.47240 7.69195  1.000 59.21883  ? 292 GLN A CG    1 
ATOM   2376 C  CD    . GLN A 1 295 ? 5.46388   -17.40714 7.91353  1.000 67.20405  ? 292 GLN A CD    1 
ATOM   2377 O  OE1   . GLN A 1 295 ? 5.93222   -16.91203 8.94131  1.000 66.97529  ? 292 GLN A OE1   1 
ATOM   2378 N  NE2   . GLN A 1 295 ? 6.22546   -17.89582 6.94279  1.000 60.04012  ? 292 GLN A NE2   1 
ATOM   2379 N  N     . GLU A 1 296 ? 1.44439   -18.55450 11.28073 1.000 32.62285  ? 293 GLU A N     1 
ATOM   2380 C  CA    . GLU A 1 296 ? 1.22992   -19.47501 12.38710 1.000 35.13737  ? 293 GLU A CA    1 
ATOM   2381 C  C     . GLU A 1 296 ? -0.11995  -20.16632 12.27620 1.000 35.16346  ? 293 GLU A C     1 
ATOM   2382 O  O     . GLU A 1 296 ? -0.25133  -21.34683 12.63302 1.000 34.74971  ? 293 GLU A O     1 
ATOM   2383 C  CB    . GLU A 1 296 ? 1.34819   -18.71766 13.70901 1.000 31.20333  ? 293 GLU A CB    1 
ATOM   2384 C  CG    . GLU A 1 296 ? 2.78429   -18.47575 14.11330 1.000 41.72183  ? 293 GLU A CG    1 
ATOM   2385 C  CD    . GLU A 1 296 ? 3.51719   -19.76273 14.45947 1.000 58.76795  ? 293 GLU A CD    1 
ATOM   2386 O  OE1   . GLU A 1 296 ? 2.89996   -20.66880 15.06959 1.000 62.27141  ? 293 GLU A OE1   1 
ATOM   2387 O  OE2   . GLU A 1 296 ? 4.70662   -19.87817 14.09328 1.000 59.68109  ? 293 GLU A OE2   1 
ATOM   2388 N  N     . MET A 1 297 ? -1.12703  -19.44671 11.78400 1.000 29.36348  ? 294 MET A N     1 
ATOM   2389 C  CA    . MET A 1 297 ? -2.42602  -20.04773 11.51173 1.000 31.39948  ? 294 MET A CA    1 
ATOM   2390 C  C     . MET A 1 297 ? -2.31064  -21.10710 10.42243 1.000 36.41561  ? 294 MET A C     1 
ATOM   2391 O  O     . MET A 1 297 ? -2.93345  -22.17483 10.50661 1.000 34.56680  ? 294 MET A O     1 
ATOM   2392 C  CB    . MET A 1 297 ? -3.40379  -18.93506 11.11823 1.000 30.27072  ? 294 MET A CB    1 
ATOM   2393 C  CG    . MET A 1 297 ? -3.97937  -18.16845 12.31328 1.000 31.20990  ? 294 MET A CG    1 
ATOM   2394 S  SD    . MET A 1 297 ? -5.03410  -16.76731 11.83921 1.000 33.83775  ? 294 MET A SD    1 
ATOM   2395 C  CE    . MET A 1 297 ? -6.48742  -17.24119 12.75888 1.000 32.29327  ? 294 MET A CE    1 
ATOM   2396 N  N     . ALA A 1 298 ? -1.48847  -20.84397 9.40231  1.000 32.74311  ? 295 ALA A N     1 
ATOM   2397 C  CA    . ALA A 1 298 ? -1.31472  -21.81901 8.32796  1.000 34.56295  ? 295 ALA A CA    1 
ATOM   2398 C  C     . ALA A 1 298 ? -0.55904  -23.04603 8.82330  1.000 43.46531  ? 295 ALA A C     1 
ATOM   2399 O  O     . ALA A 1 298 ? -0.84542  -24.17338 8.39836  1.000 42.13552  ? 295 ALA A O     1 
ATOM   2400 C  CB    . ALA A 1 298 ? -0.59549  -21.17277 7.13536  1.000 35.40480  ? 295 ALA A CB    1 
ATOM   2401 N  N     . LYS A 1 299 ? 0.40255   -22.84488 9.73025  1.000 37.25216  ? 296 LYS A N     1 
ATOM   2402 C  CA    . LYS A 1 299 ? 1.08111   -23.96691 10.37428 1.000 41.78448  ? 296 LYS A CA    1 
ATOM   2403 C  C     . LYS A 1 299 ? 0.10023   -24.82914 11.15257 1.000 48.41564  ? 296 LYS A C     1 
ATOM   2404 O  O     . LYS A 1 299 ? 0.16219   -26.06556 11.09761 1.000 39.00185  ? 296 LYS A O     1 
ATOM   2405 C  CB    . LYS A 1 299 ? 2.16853   -23.44964 11.31361 1.000 40.67372  ? 296 LYS A CB    1 
ATOM   2406 C  CG    . LYS A 1 299 ? 3.13184   -24.51198 11.81667 1.000 49.86439  ? 296 LYS A CG    1 
ATOM   2407 C  CD    . LYS A 1 299 ? 4.42314   -23.87947 12.32152 1.000 58.17324  ? 296 LYS A CD    1 
ATOM   2408 C  CE    . LYS A 1 299 ? 5.20374   -23.21307 11.19726 1.000 74.38132  ? 296 LYS A CE    1 
ATOM   2409 N  NZ    . LYS A 1 299 ? 6.48673   -22.63305 11.69757 1.000 78.95772  ? 296 LYS A NZ    1 
ATOM   2410 N  N     . PHE A 1 300 ? -0.80488  -24.19190 11.89726 1.000 35.82569  ? 297 PHE A N     1 
ATOM   2411 C  CA    . PHE A 1 300 ? -1.75052  -24.93967 12.71723 1.000 38.90189  ? 297 PHE A CA    1 
ATOM   2412 C  C     . PHE A 1 300 ? -2.66114  -25.80910 11.85792 1.000 45.77095  ? 297 PHE A C     1 
ATOM   2413 O  O     . PHE A 1 300 ? -2.82923  -27.00773 12.12430 1.000 39.42341  ? 297 PHE A O     1 
ATOM   2414 C  CB    . PHE A 1 300 ? -2.58403  -23.98837 13.56739 1.000 30.53613  ? 297 PHE A CB    1 
ATOM   2415 C  CG    . PHE A 1 300 ? -3.50527  -24.69716 14.51536 1.000 37.38245  ? 297 PHE A CG    1 
ATOM   2416 C  CD1   . PHE A 1 300 ? -3.06964  -25.04315 15.78235 1.000 39.19836  ? 297 PHE A CD1   1 
ATOM   2417 C  CD2   . PHE A 1 300 ? -4.79334  -25.04476 14.13354 1.000 36.68592  ? 297 PHE A CD2   1 
ATOM   2418 C  CE1   . PHE A 1 300 ? -3.90375  -25.70825 16.66143 1.000 41.94867  ? 297 PHE A CE1   1 
ATOM   2419 C  CE2   . PHE A 1 300 ? -5.62981  -25.71371 15.00884 1.000 36.89230  ? 297 PHE A CE2   1 
ATOM   2420 C  CZ    . PHE A 1 300 ? -5.18370  -26.04320 16.26687 1.000 41.37221  ? 297 PHE A CZ    1 
ATOM   2421 N  N     . ILE A 1 301 ? -3.27432  -25.20949 10.83138 1.000 39.69359  ? 298 ILE A N     1 
ATOM   2422 C  CA    . ILE A 1 301 ? -4.16506  -25.94321 9.93562  1.000 39.20433  ? 298 ILE A CA    1 
ATOM   2423 C  C     . ILE A 1 301 ? -3.47900  -27.19138 9.40588  1.000 53.18900  ? 298 ILE A C     1 
ATOM   2424 O  O     . ILE A 1 301 ? -4.07894  -28.27038 9.33663  1.000 46.44025  ? 298 ILE A O     1 
ATOM   2425 C  CB    . ILE A 1 301 ? -4.61803  -25.03517 8.77933  1.000 43.91586  ? 298 ILE A CB    1 
ATOM   2426 C  CG1   . ILE A 1 301 ? -5.73485  -24.10128 9.22410  1.000 55.88647  ? 298 ILE A CG1   1 
ATOM   2427 C  CG2   . ILE A 1 301 ? -5.07710  -25.86539 7.58956  1.000 57.86667  ? 298 ILE A CG2   1 
ATOM   2428 C  CD1   . ILE A 1 301 ? -6.19346  -23.20457 8.10181  1.000 53.99542  ? 298 ILE A CD1   1 
ATOM   2429 N  N     . SER A 1 302 ? -2.20834  -27.06198 9.02328  1.000 51.15759  ? 299 SER A N     1 
ATOM   2430 C  CA    . SER A 1 302 ? -1.49992  -28.16868 8.39651  1.000 61.39637  ? 299 SER A CA    1 
ATOM   2431 C  C     . SER A 1 302 ? -1.19556  -29.30158 9.37134  1.000 55.96066  ? 299 SER A C     1 
ATOM   2432 O  O     . SER A 1 302 ? -0.98302  -30.43574 8.93255  1.000 57.65250  ? 299 SER A O     1 
ATOM   2433 C  CB    . SER A 1 302 ? -0.21979  -27.64122 7.74788  1.000 55.08865  ? 299 SER A CB    1 
ATOM   2434 O  OG    . SER A 1 302 ? -0.52433  -26.56954 6.86030  1.000 61.35473  ? 299 SER A OG    1 
ATOM   2435 N  N     . ASN A 1 303 ? -1.19775  -29.04011 10.67702 1.000 55.47153  ? 300 ASN A N     1 
ATOM   2436 C  CA    . ASN A 1 303 ? -0.93691  -30.08146 11.66285 1.000 57.27812  ? 300 ASN A CA    1 
ATOM   2437 C  C     . ASN A 1 303 ? -2.17864  -30.48199 12.44988 1.000 55.16452  ? 300 ASN A C     1 
ATOM   2438 O  O     . ASN A 1 303 ? -2.06975  -31.27083 13.39445 1.000 55.83853  ? 300 ASN A O     1 
ATOM   2439 C  CB    . ASN A 1 303 ? 0.17478   -29.64604 12.62037 1.000 62.27217  ? 300 ASN A CB    1 
ATOM   2440 C  CG    . ASN A 1 303 ? 1.23317   -28.80057 11.93671 1.000 67.39680  ? 300 ASN A CG    1 
ATOM   2441 O  OD1   . ASN A 1 303 ? 1.51551   -28.97728 10.74799 1.000 72.67936  ? 300 ASN A OD1   1 
ATOM   2442 N  ND2   . ASN A 1 303 ? 1.83648   -27.88604 12.68840 1.000 67.45032  ? 300 ASN A ND2   1 
ATOM   2443 N  N     . ASN A 1 304 ? -3.36421  -29.97111 12.07935 1.000 54.14737  ? 301 ASN A N     1 
ATOM   2444 C  CA    . ASN A 1 304 ? -4.61754  -30.28085 12.78356 1.000 54.88629  ? 301 ASN A CA    1 
ATOM   2445 C  C     . ASN A 1 304 ? -5.74145  -30.40351 11.75354 1.000 49.60537  ? 301 ASN A C     1 
ATOM   2446 O  O     . ASN A 1 304 ? -6.60497  -29.53681 11.62107 1.000 50.83313  ? 301 ASN A O     1 
ATOM   2447 C  CB    . ASN A 1 304 ? -4.93653  -29.23431 13.84821 1.000 52.28700  ? 301 ASN A CB    1 
ATOM   2448 C  CG    . ASN A 1 304 ? -3.85752  -29.13691 14.90398 1.000 57.80463  ? 301 ASN A CG    1 
ATOM   2449 O  OD1   . ASN A 1 304 ? -3.95262  -29.77766 15.95198 1.000 48.03230  ? 301 ASN A OD1   1 
ATOM   2450 N  ND2   . ASN A 1 304 ? -2.82553  -28.34177 14.63753 1.000 47.23273  ? 301 ASN A ND2   1 
ATOM   2451 N  N     . GLU A 1 305 ? -5.75907  -31.52511 11.04342 1.000 51.76601  ? 302 GLU A N     1 
ATOM   2452 C  CA    . GLU A 1 305 ? -6.67529  -31.64531 9.91945  1.000 52.67647  ? 302 GLU A CA    1 
ATOM   2453 C  C     . GLU A 1 305 ? -8.10950  -31.95479 10.32864 1.000 45.70820  ? 302 GLU A C     1 
ATOM   2454 O  O     . GLU A 1 305 ? -9.01477  -31.77573 9.50533  1.000 55.60035  ? 302 GLU A O     1 
ATOM   2455 C  CB    . GLU A 1 305 ? -6.11898  -32.67171 8.93298  1.000 71.47009  ? 302 GLU A CB    1 
ATOM   2456 C  CG    . GLU A 1 305 ? -4.72477  -32.23352 8.50659  1.000 78.90264  ? 302 GLU A CG    1 
ATOM   2457 C  CD    . GLU A 1 305 ? -4.37638  -32.59620 7.08003  1.000 100.93470 ? 302 GLU A CD    1 
ATOM   2458 O  OE1   . GLU A 1 305 ? -5.24937  -32.45537 6.19458  1.000 108.32438 ? 302 GLU A OE1   1 
ATOM   2459 O  OE2   . GLU A 1 305 ? -3.19610  -32.91524 6.82409  1.000 103.45742 ? 302 GLU A OE2   1 
ATOM   2460 N  N     . HIS A 1 306 ? -8.35297  -32.35191 11.57591 1.000 39.73394  ? 303 HIS A N     1 
ATOM   2461 C  CA    . HIS A 1 306 ? -9.73087  -32.44534 12.04693 1.000 53.51578  ? 303 HIS A CA    1 
ATOM   2462 C  C     . HIS A 1 306 ? -10.32604 -31.07644 12.39085 1.000 50.00371  ? 303 HIS A C     1 
ATOM   2463 O  O     . HIS A 1 306 ? -11.49801 -31.00672 12.77626 1.000 45.76156  ? 303 HIS A O     1 
ATOM   2464 C  CB    . HIS A 1 306 ? -9.82953  -33.40288 13.25153 1.000 45.57626  ? 303 HIS A CB    1 
ATOM   2465 C  CG    . HIS A 1 306 ? -9.17895  -32.90071 14.50761 1.000 52.37447  ? 303 HIS A CG    1 
ATOM   2466 N  ND1   . HIS A 1 306 ? -7.88447  -32.42609 14.54872 1.000 64.44742  ? 303 HIS A ND1   1 
ATOM   2467 C  CD2   . HIS A 1 306 ? -9.64021  -32.83593 15.78153 1.000 56.61781  ? 303 HIS A CD2   1 
ATOM   2468 C  CE1   . HIS A 1 306 ? -7.58633  -32.06194 15.78514 1.000 58.11602  ? 303 HIS A CE1   1 
ATOM   2469 N  NE2   . HIS A 1 306 ? -8.63511  -32.29926 16.55331 1.000 59.64686  ? 303 HIS A NE2   1 
ATOM   2470 N  N     . VAL A 1 307 ? -9.56565  -29.99206 12.22866 1.000 42.93668  ? 304 VAL A N     1 
ATOM   2471 C  CA    . VAL A 1 307 ? -10.03377 -28.63413 12.50601 1.000 43.93150  ? 304 VAL A CA    1 
ATOM   2472 C  C     . VAL A 1 307 ? -10.17235 -27.87447 11.19101 1.000 44.73558  ? 304 VAL A C     1 
ATOM   2473 O  O     . VAL A 1 307 ? -9.18960  -27.69225 10.45928 1.000 44.57470  ? 304 VAL A O     1 
ATOM   2474 C  CB    . VAL A 1 307 ? -9.08676  -27.88938 13.45705 1.000 49.15678  ? 304 VAL A CB    1 
ATOM   2475 C  CG1   . VAL A 1 307 ? -9.53802  -26.42031 13.63395 1.000 41.05370  ? 304 VAL A CG1   1 
ATOM   2476 C  CG2   . VAL A 1 307 ? -9.01186  -28.60919 14.78319 1.000 43.16567  ? 304 VAL A CG2   1 
ATOM   2477 N  N     . SER A 1 308 ? -11.39240 -27.43412 10.89069 1.000 40.92542  ? 305 SER A N     1 
ATOM   2478 C  CA    . SER A 1 308 ? -11.65385 -26.51788 9.78786  1.000 40.20098  ? 305 SER A CA    1 
ATOM   2479 C  C     . SER A 1 308 ? -11.68941 -25.10585 10.36917 1.000 40.77505  ? 305 SER A C     1 
ATOM   2480 O  O     . SER A 1 308 ? -12.48964 -24.82001 11.26519 1.000 44.41425  ? 305 SER A O     1 
ATOM   2481 C  CB    . SER A 1 308 ? -12.97193 -26.85613 9.09143  1.000 40.57690  ? 305 SER A CB    1 
ATOM   2482 O  OG    . SER A 1 308 ? -12.93262 -28.15277 8.51046  1.000 48.96376  ? 305 SER A OG    1 
ATOM   2483 N  N     . LEU A 1 309 ? -10.80567 -24.24253 9.88810  1.000 35.30280  ? 306 LEU A N     1 
ATOM   2484 C  CA    . LEU A 1 309 ? -10.67317 -22.88345 10.39856 1.000 34.97778  ? 306 LEU A CA    1 
ATOM   2485 C  C     . LEU A 1 309 ? -11.43012 -21.91904 9.49172  1.000 34.93446  ? 306 LEU A C     1 
ATOM   2486 O  O     . LEU A 1 309 ? -11.28462 -21.97636 8.26926  1.000 31.71103  ? 306 LEU A O     1 
ATOM   2487 C  CB    . LEU A 1 309 ? -9.19679  -22.49515 10.46769 1.000 30.14550  ? 306 LEU A CB    1 
ATOM   2488 C  CG    . LEU A 1 309 ? -8.82988  -21.10326 10.95507 1.000 38.30096  ? 306 LEU A CG    1 
ATOM   2489 C  CD1   . LEU A 1 309 ? -9.40681  -20.83709 12.34882 1.000 41.47331  ? 306 LEU A CD1   1 
ATOM   2490 C  CD2   . LEU A 1 309 ? -7.32262  -20.93937 10.91553 1.000 39.12634  ? 306 LEU A CD2   1 
ATOM   2491 N  N     . CYS A 1 310 ? -12.23407 -21.03710 10.09016 1.000 32.83551  ? 307 CYS A N     1 
ATOM   2492 C  CA    . CYS A 1 310 ? -12.97888 -20.02129 9.35117  1.000 32.62727  ? 307 CYS A CA    1 
ATOM   2493 C  C     . CYS A 1 310 ? -12.66063 -18.66820 9.96270  1.000 28.23755  ? 307 CYS A C     1 
ATOM   2494 O  O     . CYS A 1 310 ? -12.88087 -18.47033 11.16021 1.000 29.32497  ? 307 CYS A O     1 
ATOM   2495 C  CB    . CYS A 1 310 ? -14.48582 -20.27360 9.42053  1.000 31.82493  ? 307 CYS A CB    1 
ATOM   2496 S  SG    . CYS A 1 310 ? -15.00050 -21.80361 8.62072  1.000 43.10634  ? 307 CYS A SG    1 
ATOM   2497 N  N     . ILE A 1 311 ? -12.16042 -17.74256 9.14832  1.000 29.88168  ? 308 ILE A N     1 
ATOM   2498 C  CA    . ILE A 1 311 ? -11.78442 -16.41029 9.60962  1.000 28.16062  ? 308 ILE A CA    1 
ATOM   2499 C  C     . ILE A 1 311 ? -12.69913 -15.38880 8.95215  1.000 29.18772  ? 308 ILE A C     1 
ATOM   2500 O  O     . ILE A 1 311 ? -12.76987 -15.31094 7.72017  1.000 32.65436  ? 308 ILE A O     1 
ATOM   2501 C  CB    . ILE A 1 311 ? -10.31278 -16.09532 9.31251  1.000 29.27690  ? 308 ILE A CB    1 
ATOM   2502 C  CG1   . ILE A 1 311 ? -9.41320  -17.06675 10.07675 1.000 36.45294  ? 308 ILE A CG1   1 
ATOM   2503 C  CG2   . ILE A 1 311 ? -10.00288 -14.62864 9.68471  1.000 26.10038  ? 308 ILE A CG2   1 
ATOM   2504 C  CD1   . ILE A 1 311 ? -8.19711  -17.50512 9.30972  1.000 38.06732  ? 308 ILE A CD1   1 
ATOM   2505 N  N     . PHE A 1 312 ? -13.41959 -14.63205 9.77265  1.000 27.63108  ? 309 PHE A N     1 
ATOM   2506 C  CA    . PHE A 1 312 ? -14.15895 -13.45541 9.33368  1.000 27.70746  ? 309 PHE A CA    1 
ATOM   2507 C  C     . PHE A 1 312 ? -13.46594 -12.23672 9.91172  1.000 26.97100  ? 309 PHE A C     1 
ATOM   2508 O  O     . PHE A 1 312 ? -13.19602 -12.19684 11.11642 1.000 27.19897  ? 309 PHE A O     1 
ATOM   2509 C  CB    . PHE A 1 312 ? -15.61221 -13.48321 9.80483  1.000 26.33964  ? 309 PHE A CB    1 
ATOM   2510 C  CG    . PHE A 1 312 ? -16.44975 -14.54089 9.15757  1.000 32.51340  ? 309 PHE A CG    1 
ATOM   2511 C  CD1   . PHE A 1 312 ? -17.06097 -14.30421 7.93630  1.000 33.47081  ? 309 PHE A CD1   1 
ATOM   2512 C  CD2   . PHE A 1 312 ? -16.64394 -15.76611 9.78075  1.000 27.68478  ? 309 PHE A CD2   1 
ATOM   2513 C  CE1   . PHE A 1 312 ? -17.84399 -15.27377 7.33960  1.000 35.60738  ? 309 PHE A CE1   1 
ATOM   2514 C  CE2   . PHE A 1 312 ? -17.42374 -16.74553 9.18557  1.000 31.42276  ? 309 PHE A CE2   1 
ATOM   2515 C  CZ    . PHE A 1 312 ? -18.02566 -16.49420 7.96463  1.000 37.15295  ? 309 PHE A CZ    1 
ATOM   2516 N  N     . ALA A 1 313 ? -13.19451 -11.24485 9.06648  1.000 28.48793  ? 310 ALA A N     1 
ATOM   2517 C  CA    . ALA A 1 313 ? -12.48984 -10.04133 9.48407  1.000 28.86593  ? 310 ALA A CA    1 
ATOM   2518 C  C     . ALA A 1 313 ? -13.36484 -8.81577  9.25634  1.000 27.75754  ? 310 ALA A C     1 
ATOM   2519 O  O     . ALA A 1 313 ? -14.07549 -8.72795  8.24682  1.000 26.80901  ? 310 ALA A O     1 
ATOM   2520 C  CB    . ALA A 1 313 ? -11.16660 -9.88829  8.72523  1.000 24.22309  ? 310 ALA A CB    1 
ATOM   2521 N  N     . ALA A 1 314 ? -13.30921 -7.86337  10.19746 1.000 24.51258  ? 311 ALA A N     1 
ATOM   2522 C  CA    . ALA A 1 314 ? -14.02777 -6.60602  10.00168 1.000 28.88026  ? 311 ALA A CA    1 
ATOM   2523 C  C     . ALA A 1 314 ? -13.31576 -5.72242  8.98552  1.000 24.60565  ? 311 ALA A C     1 
ATOM   2524 O  O     . ALA A 1 314 ? -13.95203 -5.13215  8.10169  1.000 26.84668  ? 311 ALA A O     1 
ATOM   2525 C  CB    . ALA A 1 314 ? -14.16778 -5.86730  11.33610 1.000 24.34522  ? 311 ALA A CB    1 
ATOM   2526 N  N     . ARG A 1 315 ? -11.99385 -5.62714  9.10276  1.000 24.34657  ? 312 ARG A N     1 
ATOM   2527 C  CA    . ARG A 1 315 ? -11.15738 -4.77631  8.27448  1.000 27.18049  ? 312 ARG A CA    1 
ATOM   2528 C  C     . ARG A 1 315 ? -9.93202  -5.56666  7.84944  1.000 26.17382  ? 312 ARG A C     1 
ATOM   2529 O  O     . ARG A 1 315 ? -9.53925  -6.52161  8.51562  1.000 23.12607  ? 312 ARG A O     1 
ATOM   2530 C  CB    . ARG A 1 315 ? -10.71579 -3.52199  9.03685  1.000 22.79594  ? 312 ARG A CB    1 
ATOM   2531 C  CG    . ARG A 1 315 ? -11.84020 -2.56049  9.41092  1.000 22.07442  ? 312 ARG A CG    1 
ATOM   2532 C  CD    . ARG A 1 315 ? -11.26645 -1.33835  10.16427 1.000 22.03685  ? 312 ARG A CD    1 
ATOM   2533 N  NE    . ARG A 1 315 ? -10.54852 -1.75422  11.36256 1.000 20.75209  ? 312 ARG A NE    1 
ATOM   2534 C  CZ    . ARG A 1 315 ? -11.15689 -2.12005  12.48420 1.000 22.49908  ? 312 ARG A CZ    1 
ATOM   2535 N  NH1   . ARG A 1 315 ? -12.47495 -2.07405  12.60144 1.000 22.54269  ? 312 ARG A NH1   1 
ATOM   2536 N  NH2   . ARG A 1 315 ? -10.42872 -2.53445  13.51513 1.000 21.04704  ? 312 ARG A NH2   1 
ATOM   2537 N  N     . ILE A 1 316 ? -9.30231  -5.13476  6.75822  1.000 23.95784  ? 313 ILE A N     1 
ATOM   2538 C  CA    . ILE A 1 316 ? -8.04668  -5.72539  6.29767  1.000 28.05414  ? 313 ILE A CA    1 
ATOM   2539 C  C     . ILE A 1 316 ? -6.88123  -4.93362  6.87673  1.000 29.90130  ? 313 ILE A C     1 
ATOM   2540 O  O     . ILE A 1 316 ? -6.77429  -3.72130  6.65566  1.000 27.45971  ? 313 ILE A O     1 
ATOM   2541 C  CB    . ILE A 1 316 ? -7.96270  -5.74935  4.76699  1.000 29.22998  ? 313 ILE A CB    1 
ATOM   2542 C  CG1   . ILE A 1 316 ? -9.03540  -6.67594  4.19598  1.000 26.57995  ? 313 ILE A CG1   1 
ATOM   2543 C  CG2   . ILE A 1 316 ? -6.56175  -6.14731  4.32861  1.000 27.33896  ? 313 ILE A CG2   1 
ATOM   2544 C  CD1   . ILE A 1 316 ? -9.30852  -6.42884  2.71245  1.000 27.33367  ? 313 ILE A CD1   1 
ATOM   2545 N  N     . TYR A 1 317 ? -5.97847  -5.61193  7.58298  1.000 25.06115  ? 314 TYR A N     1 
ATOM   2546 C  CA    . TYR A 1 317 ? -4.83384  -4.92985  8.17669  1.000 24.49478  ? 314 TYR A CA    1 
ATOM   2547 C  C     . TYR A 1 317 ? -3.63990  -5.01157  7.23572  1.000 28.13401  ? 314 TYR A C     1 
ATOM   2548 O  O     . TYR A 1 317 ? -3.15506  -6.10762  6.93253  1.000 25.65258  ? 314 TYR A O     1 
ATOM   2549 C  CB    . TYR A 1 317 ? -4.45827  -5.51622  9.53748  1.000 24.22010  ? 314 TYR A CB    1 
ATOM   2550 C  CG    . TYR A 1 317 ? -3.23683  -4.83150  10.12675 1.000 29.71086  ? 314 TYR A CG    1 
ATOM   2551 C  CD1   . TYR A 1 317 ? -3.22320  -3.45424  10.34355 1.000 26.23061  ? 314 TYR A CD1   1 
ATOM   2552 C  CD2   . TYR A 1 317 ? -2.08986  -5.55342  10.43293 1.000 33.13847  ? 314 TYR A CD2   1 
ATOM   2553 C  CE1   . TYR A 1 317 ? -2.10813  -2.82204  10.86536 1.000 30.85996  ? 314 TYR A CE1   1 
ATOM   2554 C  CE2   . TYR A 1 317 ? -0.97265  -4.92922  10.95366 1.000 26.89348  ? 314 TYR A CE2   1 
ATOM   2555 C  CZ    . TYR A 1 317 ? -0.98777  -3.57088  11.17309 1.000 27.12251  ? 314 TYR A CZ    1 
ATOM   2556 O  OH    . TYR A 1 317 ? 0.12738   -2.96154  11.68951 1.000 42.61379  ? 314 TYR A OH    1 
ATOM   2557 N  N     . ASP A 1 318 ? -3.17057  -3.85013  6.77996  1.000 29.16689  ? 315 ASP A N     1 
ATOM   2558 C  CA    . ASP A 1 318 ? -1.94677  -3.74168  5.99136  1.000 27.89870  ? 315 ASP A CA    1 
ATOM   2559 C  C     . ASP A 1 318 ? -0.78047  -3.59713  6.96595  1.000 32.08956  ? 315 ASP A C     1 
ATOM   2560 O  O     . ASP A 1 318 ? -0.63286  -2.56035  7.62020  1.000 30.71378  ? 315 ASP A O     1 
ATOM   2561 C  CB    . ASP A 1 318 ? -2.05705  -2.55540  5.02815  1.000 35.52940  ? 315 ASP A CB    1 
ATOM   2562 C  CG    . ASP A 1 318 ? -0.79620  -2.31937  4.20111  1.000 38.12039  ? 315 ASP A CG    1 
ATOM   2563 O  OD1   . ASP A 1 318 ? 0.25210   -2.95326  4.43888  1.000 35.42507  ? 315 ASP A OD1   1 
ATOM   2564 O  OD2   . ASP A 1 318 ? -0.87375  -1.50480  3.26278  1.000 46.19766  ? 315 ASP A OD2   1 
ATOM   2565 N  N     . ASP A 1 319 ? 0.04860   -4.63637  7.07059  1.000 31.08090  ? 316 ASP A N     1 
ATOM   2566 C  CA    . ASP A 1 319 ? 1.14043   -4.65676  8.03631  1.000 34.84342  ? 316 ASP A CA    1 
ATOM   2567 C  C     . ASP A 1 319 ? 2.42594   -4.03329  7.49615  1.000 35.23883  ? 316 ASP A C     1 
ATOM   2568 O  O     . ASP A 1 319 ? 3.48655   -4.19994  8.10619  1.000 39.99531  ? 316 ASP A O     1 
ATOM   2569 C  CB    . ASP A 1 319 ? 1.39975   -6.09364  8.52382  1.000 32.50623  ? 316 ASP A CB    1 
ATOM   2570 C  CG    . ASP A 1 319 ? 1.84493   -7.04236  7.40829  1.000 37.83922  ? 316 ASP A CG    1 
ATOM   2571 O  OD1   . ASP A 1 319 ? 1.92091   -6.62081  6.23155  1.000 33.90273  ? 316 ASP A OD1   1 
ATOM   2572 O  OD2   . ASP A 1 319 ? 2.13333   -8.22445  7.71559  1.000 33.55452  ? 316 ASP A OD2   1 
ATOM   2573 N  N     . GLN A 1 320 ? 2.35073   -3.30740  6.37865  1.000 33.64329  ? 317 GLN A N     1 
ATOM   2574 C  CA    . GLN A 1 320 ? 3.51316   -2.75912  5.67140  1.000 42.31556  ? 317 GLN A CA    1 
ATOM   2575 C  C     . GLN A 1 320 ? 4.48659   -3.84181  5.23265  1.000 45.64810  ? 317 GLN A C     1 
ATOM   2576 O  O     . GLN A 1 320 ? 5.64156   -3.54828  4.90852  1.000 48.72801  ? 317 GLN A O     1 
ATOM   2577 C  CB    . GLN A 1 320 ? 4.26280   -1.70081  6.49809  1.000 45.15629  ? 317 GLN A CB    1 
ATOM   2578 C  CG    . GLN A 1 320 ? 3.42778   -0.94255  7.49968  1.000 51.09164  ? 317 GLN A CG    1 
ATOM   2579 C  CD    . GLN A 1 320 ? 2.54679   0.09387   6.83821  1.000 60.87708  ? 317 GLN A CD    1 
ATOM   2580 O  OE1   . GLN A 1 320 ? 1.33796   0.14399   7.07364  1.000 66.99944  ? 317 GLN A OE1   1 
ATOM   2581 N  NE2   . GLN A 1 320 ? 3.14904   0.93189   6.00390  1.000 68.53919  ? 317 GLN A NE2   1 
ATOM   2582 N  N     . GLY A 1 321 ? 4.03427   -5.08969  5.20012  1.000 43.94106  ? 318 GLY A N     1 
ATOM   2583 C  CA    . GLY A 1 321 ? 4.88582   -6.19828  4.83220  1.000 40.61139  ? 318 GLY A CA    1 
ATOM   2584 C  C     . GLY A 1 321 ? 4.15432   -7.19499  3.96251  1.000 43.94655  ? 318 GLY A C     1 
ATOM   2585 O  O     . GLY A 1 321 ? 3.52345   -6.81620  2.97131  1.000 44.34695  ? 318 GLY A O     1 
ATOM   2586 N  N     . ARG A 1 322 ? 4.20182   -8.47248  4.33851  1.000 38.65302  ? 319 ARG A N     1 
ATOM   2587 C  CA    . ARG A 1 322 ? 3.76195   -9.55046  3.46341  1.000 40.56253  ? 319 ARG A CA    1 
ATOM   2588 C  C     . ARG A 1 322 ? 2.34525   -10.02605 3.76988  1.000 42.15636  ? 319 ARG A C     1 
ATOM   2589 O  O     . ARG A 1 322 ? 2.02850   -11.19405 3.52657  1.000 36.12015  ? 319 ARG A O     1 
ATOM   2590 C  CB    . ARG A 1 322 ? 4.74639   -10.71897 3.55117  1.000 44.02014  ? 319 ARG A CB    1 
ATOM   2591 C  CG    . ARG A 1 322 ? 6.16315   -10.36540 3.09344  1.000 47.79595  ? 319 ARG A CG    1 
ATOM   2592 C  CD    . ARG A 1 322 ? 7.16627   -11.37205 3.62578  1.000 53.46228  ? 319 ARG A CD    1 
ATOM   2593 N  NE    . ARG A 1 322 ? 6.96052   -12.70751 3.07870  1.000 53.50742  ? 319 ARG A NE    1 
ATOM   2594 C  CZ    . ARG A 1 322 ? 7.69126   -13.76525 3.40751  1.000 62.96226  ? 319 ARG A CZ    1 
ATOM   2595 N  NH1   . ARG A 1 322 ? 8.60895   -13.70002 4.36212  1.000 53.72961  ? 319 ARG A NH1   1 
ATOM   2596 N  NH2   . ARG A 1 322 ? 7.48084   -14.92289 2.78124  1.000 53.54721  ? 319 ARG A NH2   1 
ATOM   2597 N  N     . TYR A 1 323 ? 1.47820   -9.14389  4.28510  1.000 33.49078  ? 320 TYR A N     1 
ATOM   2598 C  CA    . TYR A 1 323 ? 0.15255   -9.58767  4.71868  1.000 35.80291  ? 320 TYR A CA    1 
ATOM   2599 C  C     . TYR A 1 323 ? -0.66022  -10.18714 3.56849  1.000 36.83634  ? 320 TYR A C     1 
ATOM   2600 O  O     . TYR A 1 323 ? -1.45395  -11.10963 3.78856  1.000 32.68636  ? 320 TYR A O     1 
ATOM   2601 C  CB    . TYR A 1 323 ? -0.61239  -8.42777  5.36735  1.000 33.78420  ? 320 TYR A CB    1 
ATOM   2602 C  CG    . TYR A 1 323 ? -1.13614  -7.42179  4.37186  1.000 32.70802  ? 320 TYR A CG    1 
ATOM   2603 C  CD1   . TYR A 1 323 ? -0.29315  -6.47779  3.79868  1.000 34.07964  ? 320 TYR A CD1   1 
ATOM   2604 C  CD2   . TYR A 1 323 ? -2.47376  -7.41700  4.00376  1.000 28.89521  ? 320 TYR A CD2   1 
ATOM   2605 C  CE1   . TYR A 1 323 ? -0.77102  -5.55752  2.87298  1.000 37.21293  ? 320 TYR A CE1   1 
ATOM   2606 C  CE2   . TYR A 1 323 ? -2.96139  -6.50500  3.08585  1.000 38.66793  ? 320 TYR A CE2   1 
ATOM   2607 C  CZ    . TYR A 1 323 ? -2.10725  -5.57610  2.52411  1.000 41.33461  ? 320 TYR A CZ    1 
ATOM   2608 O  OH    . TYR A 1 323 ? -2.59852  -4.67488  1.60563  1.000 39.23774  ? 320 TYR A OH    1 
ATOM   2609 N  N     . GLN A 1 324 ? -0.47641  -9.69454  2.33971  1.000 34.96157  ? 321 GLN A N     1 
ATOM   2610 C  CA    . GLN A 1 324 ? -1.22371  -10.25117 1.21258  1.000 37.17624  ? 321 GLN A CA    1 
ATOM   2611 C  C     . GLN A 1 324 ? -0.82458  -11.70482 0.95554  1.000 40.72705  ? 321 GLN A C     1 
ATOM   2612 O  O     . GLN A 1 324 ? -1.68208  -12.57882 0.77193  1.000 36.38776  ? 321 GLN A O     1 
ATOM   2613 C  CB    . GLN A 1 324 ? -1.01406  -9.38554  -0.03574 1.000 38.65766  ? 321 GLN A CB    1 
ATOM   2614 C  CG    . GLN A 1 324 ? -1.60225  -7.98524  0.09747  1.000 40.70243  ? 321 GLN A CG    1 
ATOM   2615 C  CD    . GLN A 1 324 ? -1.59660  -7.20937  -1.21212 1.000 49.14201  ? 321 GLN A CD    1 
ATOM   2616 O  OE1   . GLN A 1 324 ? -1.10219  -7.68771  -2.22630 1.000 54.03029  ? 321 GLN A OE1   1 
ATOM   2617 N  NE2   . GLN A 1 324 ? -2.16468  -6.01475  -1.19306 1.000 48.38408  ? 321 GLN A NE2   1 
ATOM   2618 N  N     . GLU A 1 325 ? 0.47954   -11.98544 0.97154  1.000 40.70877  ? 322 GLU A N     1 
ATOM   2619 C  CA    . GLU A 1 325 ? 0.95057   -13.36045 0.82986  1.000 38.06571  ? 322 GLU A CA    1 
ATOM   2620 C  C     . GLU A 1 325 ? 0.48093   -14.23337 1.99033  1.000 42.29397  ? 322 GLU A C     1 
ATOM   2621 O  O     . GLU A 1 325 ? 0.11952   -15.40163 1.79458  1.000 39.81899  ? 322 GLU A O     1 
ATOM   2622 C  CB    . GLU A 1 325 ? 2.47550   -13.35894 0.72106  1.000 45.43137  ? 322 GLU A CB    1 
ATOM   2623 C  CG    . GLU A 1 325 ? 3.13690   -14.70409 0.89743  1.000 48.32116  ? 322 GLU A CG    1 
ATOM   2624 C  CD    . GLU A 1 325 ? 4.63354   -14.57759 1.10515  1.000 54.90743  ? 322 GLU A CD    1 
ATOM   2625 O  OE1   . GLU A 1 325 ? 5.15633   -13.44626 0.98978  1.000 55.52602  ? 322 GLU A OE1   1 
ATOM   2626 O  OE2   . GLU A 1 325 ? 5.28161   -15.60438 1.40022  1.000 61.28571  ? 322 GLU A OE2   1 
ATOM   2627 N  N     . GLY A 1 326 ? 0.48249   -13.68610 3.20935  1.000 38.21442  ? 323 GLY A N     1 
ATOM   2628 C  CA    . GLY A 1 326 ? -0.00643  -14.44500 4.34944  1.000 37.34490  ? 323 GLY A CA    1 
ATOM   2629 C  C     . GLY A 1 326 ? -1.46031  -14.84987 4.19815  1.000 37.19116  ? 323 GLY A C     1 
ATOM   2630 O  O     . GLY A 1 326 ? -1.83281  -15.98899 4.49133  1.000 37.63655  ? 323 GLY A O     1 
ATOM   2631 N  N     . LEU A 1 327 ? -2.29794  -13.93255 3.70745  1.000 30.36442  ? 324 LEU A N     1 
ATOM   2632 C  CA    . LEU A 1 327 ? -3.70181  -14.26570 3.47771  1.000 32.18769  ? 324 LEU A CA    1 
ATOM   2633 C  C     . LEU A 1 327 ? -3.85601  -15.27623 2.34656  1.000 40.32084  ? 324 LEU A C     1 
ATOM   2634 O  O     . LEU A 1 327 ? -4.72058  -16.16220 2.40587  1.000 34.51874  ? 324 LEU A O     1 
ATOM   2635 C  CB    . LEU A 1 327 ? -4.49135  -12.99349 3.18157  1.000 33.31883  ? 324 LEU A CB    1 
ATOM   2636 C  CG    . LEU A 1 327 ? -4.57613  -11.98827 4.33931  1.000 31.00852  ? 324 LEU A CG    1 
ATOM   2637 C  CD1   . LEU A 1 327 ? -5.40745  -10.78300 3.92058  1.000 33.10868  ? 324 LEU A CD1   1 
ATOM   2638 C  CD2   . LEU A 1 327 ? -5.16763  -12.62504 5.57811  1.000 29.59762  ? 324 LEU A CD2   1 
ATOM   2639 N  N     . ARG A 1 328 ? -3.02908  -15.16089 1.30607  1.000 38.80921  ? 325 ARG A N     1 
ATOM   2640 C  CA    . ARG A 1 328 ? -3.09048  -16.12759 0.21438  1.000 37.51117  ? 325 ARG A CA    1 
ATOM   2641 C  C     . ARG A 1 328 ? -2.66300  -17.50762 0.68475  1.000 45.87765  ? 325 ARG A C     1 
ATOM   2642 O  O     . ARG A 1 328 ? -3.29472  -18.51308 0.33228  1.000 45.80561  ? 325 ARG A O     1 
ATOM   2643 C  CB    . ARG A 1 328 ? -2.21394  -15.66214 -0.94958 1.000 38.34061  ? 325 ARG A CB    1 
ATOM   2644 C  CG    . ARG A 1 328 ? -2.89086  -14.66208 -1.87796 1.000 45.49228  ? 325 ARG A CG    1 
ATOM   2645 C  CD    . ARG A 1 328 ? -2.10442  -14.48835 -3.17165 1.000 46.63256  ? 325 ARG A CD    1 
ATOM   2646 N  NE    . ARG A 1 328 ? -0.87488  -13.72901 -2.95838 1.000 49.86866  ? 325 ARG A NE    1 
ATOM   2647 C  CZ    . ARG A 1 328 ? -0.79204  -12.40433 -2.97630 1.000 46.97830  ? 325 ARG A CZ    1 
ATOM   2648 N  NH1   . ARG A 1 328 ? -1.85715  -11.64507 -3.18070 1.000 47.91702  ? 325 ARG A NH1   1 
ATOM   2649 N  NH2   . ARG A 1 328 ? 0.39069   -11.82514 -2.78325 1.000 42.33798  ? 325 ARG A NH2   1 
ATOM   2650 N  N     . THR A 1 329 ? -1.59123  -17.57592 1.48011  1.000 39.39268  ? 326 THR A N     1 
ATOM   2651 C  CA    . THR A 1 329 ? -1.13440  -18.86488 1.99367  1.000 45.72532  ? 326 THR A CA    1 
ATOM   2652 C  C     . THR A 1 329 ? -2.19276  -19.50129 2.88776  1.000 46.84901  ? 326 THR A C     1 
ATOM   2653 O  O     . THR A 1 329 ? -2.45067  -20.70911 2.80185  1.000 43.85869  ? 326 THR A O     1 
ATOM   2654 C  CB    . THR A 1 329 ? 0.18551   -18.68645 2.75026  1.000 50.17484  ? 326 THR A CB    1 
ATOM   2655 O  OG1   . THR A 1 329 ? 1.22117   -18.31924 1.82741  1.000 47.59197  ? 326 THR A OG1   1 
ATOM   2656 C  CG2   . THR A 1 329 ? 0.58679   -19.98259 3.47474  1.000 49.76070  ? 326 THR A CG2   1 
ATOM   2657 N  N     . LEU A 1 330 ? -2.83031  -18.69512 3.73705  1.000 41.62655  ? 327 LEU A N     1 
ATOM   2658 C  CA    . LEU A 1 330 ? -3.87281  -19.19785 4.62731  1.000 39.84568  ? 327 LEU A CA    1 
ATOM   2659 C  C     . LEU A 1 330 ? -5.04311  -19.77859 3.84086  1.000 44.95982  ? 327 LEU A C     1 
ATOM   2660 O  O     . LEU A 1 330 ? -5.54138  -20.86627 4.16124  1.000 47.61084  ? 327 LEU A O     1 
ATOM   2661 C  CB    . LEU A 1 330 ? -4.34001  -18.05862 5.53316  1.000 36.38993  ? 327 LEU A CB    1 
ATOM   2662 C  CG    . LEU A 1 330 ? -5.03638  -18.30206 6.86637  1.000 40.93606  ? 327 LEU A CG    1 
ATOM   2663 C  CD1   . LEU A 1 330 ? -4.39135  -19.42989 7.66099  1.000 42.75390  ? 327 LEU A CD1   1 
ATOM   2664 C  CD2   . LEU A 1 330 ? -5.02161  -16.99412 7.64530  1.000 39.26521  ? 327 LEU A CD2   1 
ATOM   2665 N  N     . HIS A 1 331 ? -5.48181  -19.07384 2.79232  1.000 41.31975  ? 328 HIS A N     1 
ATOM   2666 C  CA    . HIS A 1 331 ? -6.59845  -19.55506 1.98170  1.000 52.14660  ? 328 HIS A CA    1 
ATOM   2667 C  C     . HIS A 1 331 ? -6.25765  -20.85332 1.25762  1.000 52.28291  ? 328 HIS A C     1 
ATOM   2668 O  O     . HIS A 1 331 ? -7.08378  -21.77451 1.19867  1.000 50.34552  ? 328 HIS A O     1 
ATOM   2669 C  CB    . HIS A 1 331 ? -7.01644  -18.48570 0.97203  1.000 47.24535  ? 328 HIS A CB    1 
ATOM   2670 C  CG    . HIS A 1 331 ? -8.27119  -18.82277 0.22916  1.000 51.63455  ? 328 HIS A CG    1 
ATOM   2671 N  ND1   . HIS A 1 331 ? -8.29306  -19.04925 -1.13065 1.000 51.65120  ? 328 HIS A ND1   1 
ATOM   2672 C  CD2   . HIS A 1 331 ? -9.54519  -18.98612 0.65886  1.000 55.56201  ? 328 HIS A CD2   1 
ATOM   2673 C  CE1   . HIS A 1 331 ? -9.52623  -19.33601 -1.50793 1.000 54.29878  ? 328 HIS A CE1   1 
ATOM   2674 N  NE2   . HIS A 1 331 ? -10.30569 -19.30297 -0.44181 1.000 59.38775  ? 328 HIS A NE2   1 
ATOM   2675 N  N     . ARG A 1 332 ? -5.05118  -20.94776 0.69153  1.000 54.69487  ? 329 ARG A N     1 
ATOM   2676 C  CA    . ARG A 1 332 ? -4.70147  -22.16028 -0.04210 1.000 58.02368  ? 329 ARG A CA    1 
ATOM   2677 C  C     . ARG A 1 332 ? -4.57879  -23.36378 0.88465  1.000 63.62122  ? 329 ARG A C     1 
ATOM   2678 O  O     . ARG A 1 332 ? -4.91943  -24.48232 0.48468  1.000 64.73741  ? 329 ARG A O     1 
ATOM   2679 C  CB    . ARG A 1 332 ? -3.40375  -21.96738 -0.83245 1.000 69.28710  ? 329 ARG A CB    1 
ATOM   2680 C  CG    . ARG A 1 332 ? -2.14835  -21.97776 0.02187  1.000 71.56294  ? 329 ARG A CG    1 
ATOM   2681 C  CD    . ARG A 1 332 ? -0.92399  -22.44665 -0.75191 1.000 82.11328  ? 329 ARG A CD    1 
ATOM   2682 N  NE    . ARG A 1 332 ? 0.28634   -22.29045 0.04814  1.000 82.39498  ? 329 ARG A NE    1 
ATOM   2683 C  CZ    . ARG A 1 332 ? 0.88644   -23.27575 0.70284  1.000 81.15685  ? 329 ARG A CZ    1 
ATOM   2684 N  NH1   . ARG A 1 332 ? 0.43584   -24.51956 0.64630  1.000 86.78152  ? 329 ARG A NH1   1 
ATOM   2685 N  NH2   . ARG A 1 332 ? 1.96473   -23.00610 1.43372  1.000 80.23443  ? 329 ARG A NH2   1 
ATOM   2686 N  N     . ASP A 1 333 ? -4.11576  -23.16518 2.12261  1.000 52.57132  ? 330 ASP A N     1 
ATOM   2687 C  CA    . ASP A 1 333 ? -4.01084  -24.27412 3.05885  1.000 47.34132  ? 330 ASP A CA    1 
ATOM   2688 C  C     . ASP A 1 333 ? -5.35498  -24.68607 3.63746  1.000 51.95631  ? 330 ASP A C     1 
ATOM   2689 O  O     . ASP A 1 333 ? -5.39869  -25.61458 4.45225  1.000 57.53930  ? 330 ASP A O     1 
ATOM   2690 C  CB    . ASP A 1 333 ? -3.02899  -23.94109 4.18736  1.000 52.27862  ? 330 ASP A CB    1 
ATOM   2691 C  CG    . ASP A 1 333 ? -1.59526  -23.84775 3.70168  1.000 55.83733  ? 330 ASP A CG    1 
ATOM   2692 O  OD1   . ASP A 1 333 ? -1.34315  -24.26409 2.55808  1.000 65.30330  ? 330 ASP A OD1   1 
ATOM   2693 O  OD2   . ASP A 1 333 ? -0.72493  -23.35256 4.44840  1.000 47.66051  ? 330 ASP A OD2   1 
ATOM   2694 N  N     . GLY A 1 334 ? -6.44538  -24.03751 3.23445  1.000 47.11881  ? 331 GLY A N     1 
ATOM   2695 C  CA    . GLY A 1 334 ? -7.77522  -24.52248 3.54184  1.000 49.46233  ? 331 GLY A CA    1 
ATOM   2696 C  C     . GLY A 1 334 ? -8.58199  -23.67281 4.49401  1.000 42.78768  ? 331 GLY A C     1 
ATOM   2697 O  O     . GLY A 1 334 ? -9.72261  -24.03974 4.79931  1.000 44.91909  ? 331 GLY A O     1 
ATOM   2698 N  N     . ALA A 1 335 ? -8.04147  -22.56524 4.99069  1.000 39.84040  ? 332 ALA A N     1 
ATOM   2699 C  CA    . ALA A 1 335 ? -8.85092  -21.66595 5.79779  1.000 38.91855  ? 332 ALA A CA    1 
ATOM   2700 C  C     . ALA A 1 335 ? -9.86664  -20.96518 4.91000  1.000 47.11016  ? 332 ALA A C     1 
ATOM   2701 O  O     . ALA A 1 335 ? -9.56264  -20.58215 3.77343  1.000 43.08023  ? 332 ALA A O     1 
ATOM   2702 C  CB    . ALA A 1 335 ? -7.97649  -20.62508 6.50001  1.000 40.98900  ? 332 ALA A CB    1 
ATOM   2703 N  N     . LYS A 1 336 ? -11.08273 -20.80426 5.41865  1.000 35.00288  ? 333 LYS A N     1 
ATOM   2704 C  CA    . LYS A 1 336 ? -12.03972 -19.92512 4.76503  1.000 37.26899  ? 333 LYS A CA    1 
ATOM   2705 C  C     . LYS A 1 336 ? -11.81465 -18.53116 5.32480  1.000 34.48628  ? 333 LYS A C     1 
ATOM   2706 O  O     . LYS A 1 336 ? -11.79153 -18.35108 6.54549  1.000 33.03862  ? 333 LYS A O     1 
ATOM   2707 C  CB    . LYS A 1 336 ? -13.47406 -20.41191 4.96681  1.000 47.53413  ? 333 LYS A CB    1 
ATOM   2708 C  CG    . LYS A 1 336 ? -13.63067 -21.90040 4.59109  1.000 55.64098  ? 333 LYS A CG    1 
ATOM   2709 C  CD    . LYS A 1 336 ? -14.62956 -22.64574 5.47738  1.000 62.21232  ? 333 LYS A CD    1 
ATOM   2710 C  CE    . LYS A 1 336 ? -14.19504 -24.07589 5.84173  1.000 55.63381  ? 333 LYS A CE    1 
ATOM   2711 N  NZ    . LYS A 1 336 ? -12.94374 -24.10210 6.67984  1.000 45.99147  ? 333 LYS A NZ    1 
ATOM   2712 N  N     . ILE A 1 337 ? -11.54947 -17.57070 4.43828  1.000 36.35164  ? 334 ILE A N     1 
ATOM   2713 C  CA    . ILE A 1 337 ? -11.32136 -16.17629 4.81691  1.000 38.90609  ? 334 ILE A CA    1 
ATOM   2714 C  C     . ILE A 1 337 ? -12.37832 -15.32944 4.13293  1.000 38.23556  ? 334 ILE A C     1 
ATOM   2715 O  O     . ILE A 1 337 ? -12.57589 -15.43879 2.91888  1.000 35.43645  ? 334 ILE A O     1 
ATOM   2716 C  CB    . ILE A 1 337 ? -9.91276  -15.68384 4.43120  1.000 38.21392  ? 334 ILE A CB    1 
ATOM   2717 C  CG1   . ILE A 1 337 ? -8.85377  -16.74627 4.75180  1.000 41.68788  ? 334 ILE A CG1   1 
ATOM   2718 C  CG2   . ILE A 1 337 ? -9.61059  -14.33180 5.08715  1.000 34.69859  ? 334 ILE A CG2   1 
ATOM   2719 C  CD1   . ILE A 1 337 ? -7.43603  -16.19891 4.76016  1.000 43.43265  ? 334 ILE A CD1   1 
ATOM   2720 N  N     . ALA A 1 338 ? -13.05363 -14.48893 4.90668  1.000 29.44225  ? 335 ALA A N     1 
ATOM   2721 C  CA    . ALA A 1 338 ? -14.11883 -13.66488 4.36174  1.000 33.50846  ? 335 ALA A CA    1 
ATOM   2722 C  C     . ALA A 1 338 ? -14.20209 -12.39763 5.19040  1.000 31.18485  ? 335 ALA A C     1 
ATOM   2723 O  O     . ALA A 1 338 ? -13.86030 -12.40070 6.37432  1.000 30.99873  ? 335 ALA A O     1 
ATOM   2724 C  CB    . ALA A 1 338 ? -15.46465 -14.39131 4.36049  1.000 31.62756  ? 335 ALA A CB    1 
ATOM   2725 N  N     . MET A 1 339 ? -14.64272 -11.31759 4.55403  1.000 31.96204  ? 336 MET A N     1 
ATOM   2726 C  CA    . MET A 1 339 ? -14.89441 -10.07479 5.26488  1.000 37.16675  ? 336 MET A CA    1 
ATOM   2727 C  C     . MET A 1 339 ? -16.24938 -10.17382 5.94778  1.000 33.81467  ? 336 MET A C     1 
ATOM   2728 O  O     . MET A 1 339 ? -17.19626 -10.74230 5.39679  1.000 35.77089  ? 336 MET A O     1 
ATOM   2729 C  CB    . MET A 1 339 ? -14.89318 -8.89093  4.28962  1.000 30.23133  ? 336 MET A CB    1 
ATOM   2730 C  CG    . MET A 1 339 ? -13.54687 -8.60190  3.64562  1.000 30.39602  ? 336 MET A CG    1 
ATOM   2731 S  SD    . MET A 1 339 ? -12.10498 -8.77567  4.69964  1.000 31.13983  ? 336 MET A SD    1 
ATOM   2732 C  CE    . MET A 1 339 ? -12.37600 -7.41719  5.86385  1.000 27.95816  ? 336 MET A CE    1 
ATOM   2733 N  N     . MET A 1 340 ? -16.34166 -9.61638  7.14408  1.000 32.11076  ? 337 MET A N     1 
ATOM   2734 C  CA    . MET A 1 340 ? -17.60556 -9.60864  7.86371  1.000 29.64067  ? 337 MET A CA    1 
ATOM   2735 C  C     . MET A 1 340 ? -18.63641 -8.76470  7.12465  1.000 34.46135  ? 337 MET A C     1 
ATOM   2736 O  O     . MET A 1 340 ? -18.34750 -7.63907  6.71236  1.000 32.93151  ? 337 MET A O     1 
ATOM   2737 C  CB    . MET A 1 340 ? -17.36546 -9.05566  9.26048  1.000 26.46309  ? 337 MET A CB    1 
ATOM   2738 C  CG    . MET A 1 340 ? -16.66525 -10.06118 10.14947 1.000 29.32595  ? 337 MET A CG    1 
ATOM   2739 S  SD    . MET A 1 340 ? -16.42238 -9.47174  11.82541 1.000 28.74541  ? 337 MET A SD    1 
ATOM   2740 C  CE    . MET A 1 340 ? -18.09566 -9.46219  12.46234 1.000 30.28664  ? 337 MET A CE    1 
ATOM   2741 N  N     . ASN A 1 341 ? -19.83693 -9.31486  6.96481  1.000 33.48392  ? 338 ASN A N     1 
ATOM   2742 C  CA    . ASN A 1 341 ? -21.00281 -8.63684  6.41907  1.000 40.21922  ? 338 ASN A CA    1 
ATOM   2743 C  C     . ASN A 1 341 ? -21.98228 -8.35190  7.55651  1.000 35.40345  ? 338 ASN A C     1 
ATOM   2744 O  O     . ASN A 1 341 ? -21.71354 -8.66938  8.71611  1.000 33.96454  ? 338 ASN A O     1 
ATOM   2745 C  CB    . ASN A 1 341 ? -21.65561 -9.49947  5.33750  1.000 44.26972  ? 338 ASN A CB    1 
ATOM   2746 C  CG    . ASN A 1 341 ? -20.99810 -9.33190  3.98841  1.000 54.75880  ? 338 ASN A CG    1 
ATOM   2747 O  OD1   . ASN A 1 341 ? -20.71877 -8.21637  3.55735  1.000 52.53499  ? 338 ASN A OD1   1 
ATOM   2748 N  ND2   . ASN A 1 341 ? -20.74190 -10.45140 3.30988  1.000 57.83775  ? 338 ASN A ND2   1 
ATOM   2749 N  N     . TYR A 1 342 ? -23.14632 -7.78132  7.21236  1.000 39.17341  ? 339 TYR A N     1 
ATOM   2750 C  CA    . TYR A 1 342 ? -24.12631 -7.42925  8.23997  1.000 35.58435  ? 339 TYR A CA    1 
ATOM   2751 C  C     . TYR A 1 342 ? -24.46425 -8.62203  9.13638  1.000 39.84960  ? 339 TYR A C     1 
ATOM   2752 O  O     . TYR A 1 342 ? -24.55490 -8.47664  10.36184 1.000 37.79909  ? 339 TYR A O     1 
ATOM   2753 C  CB    . TYR A 1 342 ? -25.40529 -6.86926  7.60119  1.000 42.47394  ? 339 TYR A CB    1 
ATOM   2754 C  CG    . TYR A 1 342 ? -26.50623 -6.54449  8.60797  1.000 44.42043  ? 339 TYR A CG    1 
ATOM   2755 C  CD1   . TYR A 1 342 ? -27.27379 -7.54523  9.19749  1.000 50.78010  ? 339 TYR A CD1   1 
ATOM   2756 C  CD2   . TYR A 1 342 ? -26.76393 -5.22853  8.97783  1.000 54.76560  ? 339 TYR A CD2   1 
ATOM   2757 C  CE1   . TYR A 1 342 ? -28.25755 -7.25019  10.12085 1.000 48.19978  ? 339 TYR A CE1   1 
ATOM   2758 C  CE2   . TYR A 1 342 ? -27.75432 -4.92402  9.90131  1.000 56.31187  ? 339 TYR A CE2   1 
ATOM   2759 C  CZ    . TYR A 1 342 ? -28.49605 -5.94234  10.46684 1.000 55.50644  ? 339 TYR A CZ    1 
ATOM   2760 O  OH    . TYR A 1 342 ? -29.48396 -5.65595  11.38357 1.000 70.41780  ? 339 TYR A OH    1 
ATOM   2761 N  N     . SER A 1 343 ? -24.67510 -9.80485  8.54739  1.000 41.03873  ? 340 SER A N     1 
ATOM   2762 C  CA    . SER A 1 343 ? -25.12508 -10.94452 9.34849  1.000 39.29771  ? 340 SER A CA    1 
ATOM   2763 C  C     . SER A 1 343 ? -24.09322 -11.33308 10.40141 1.000 38.27780  ? 340 SER A C     1 
ATOM   2764 O  O     . SER A 1 343 ? -24.45330 -11.74915 11.51135 1.000 36.75125  ? 340 SER A O     1 
ATOM   2765 C  CB    . SER A 1 343 ? -25.44812 -12.14298 8.45102  1.000 46.05392  ? 340 SER A CB    1 
ATOM   2766 O  OG    . SER A 1 343 ? -24.57789 -12.21328 7.33453  1.000 62.42613  ? 340 SER A OG    1 
ATOM   2767 N  N     . GLU A 1 344 ? -22.80453 -11.20404 10.07787 1.000 35.77822  ? 341 GLU A N     1 
ATOM   2768 C  CA    . GLU A 1 344 ? -21.76356 -11.56130 11.04120 1.000 34.52605  ? 341 GLU A CA    1 
ATOM   2769 C  C     . GLU A 1 344 ? -21.61158 -10.50521 12.12887 1.000 35.48221  ? 341 GLU A C     1 
ATOM   2770 O  O     . GLU A 1 344 ? -21.35700 -10.83863 13.29545 1.000 30.42286  ? 341 GLU A O     1 
ATOM   2771 C  CB    . GLU A 1 344 ? -20.43969 -11.77859 10.31289 1.000 34.44769  ? 341 GLU A CB    1 
ATOM   2772 C  CG    . GLU A 1 344 ? -20.42009 -13.04143 9.44908  1.000 35.52269  ? 341 GLU A CG    1 
ATOM   2773 C  CD    . GLU A 1 344 ? -20.98489 -12.80999 8.06073  1.000 41.79724  ? 341 GLU A CD    1 
ATOM   2774 O  OE1   . GLU A 1 344 ? -20.74266 -11.73168 7.47737  1.000 41.96736  ? 341 GLU A OE1   1 
ATOM   2775 O  OE2   . GLU A 1 344 ? -21.66136 -13.71723 7.54214  1.000 39.87574  ? 341 GLU A OE2   1 
ATOM   2776 N  N     . PHE A 1 345 ? -21.74492 -9.22605  11.77542 1.000 33.36107  ? 342 PHE A N     1 
ATOM   2777 C  CA    . PHE A 1 345 ? -21.73849 -8.19459  12.80792 1.000 33.07179  ? 342 PHE A CA    1 
ATOM   2778 C  C     . PHE A 1 345 ? -22.91817 -8.37908  13.75445 1.000 35.34878  ? 342 PHE A C     1 
ATOM   2779 O  O     . PHE A 1 345 ? -22.76766 -8.29288  14.97903 1.000 33.77051  ? 342 PHE A O     1 
ATOM   2780 C  CB    . PHE A 1 345 ? -21.77522 -6.80048  12.17758 1.000 29.44540  ? 342 PHE A CB    1 
ATOM   2781 C  CG    . PHE A 1 345 ? -20.51293 -6.41766  11.44915 1.000 26.89902  ? 342 PHE A CG    1 
ATOM   2782 C  CD1   . PHE A 1 345 ? -19.30930 -6.28862  12.12555 1.000 27.81830  ? 342 PHE A CD1   1 
ATOM   2783 C  CD2   . PHE A 1 345 ? -20.54145 -6.15763  10.08289 1.000 32.65953  ? 342 PHE A CD2   1 
ATOM   2784 C  CE1   . PHE A 1 345 ? -18.14776 -5.92942  11.45408 1.000 26.35226  ? 342 PHE A CE1   1 
ATOM   2785 C  CE2   . PHE A 1 345 ? -19.38688 -5.78779  9.40374  1.000 32.09480  ? 342 PHE A CE2   1 
ATOM   2786 C  CZ    . PHE A 1 345 ? -18.18959 -5.67783  10.08999 1.000 26.51013  ? 342 PHE A CZ    1 
ATOM   2787 N  N     . GLU A 1 346 ? -24.10870 -8.62617  13.19846 1.000 35.34158  ? 343 GLU A N     1 
ATOM   2788 C  CA    . GLU A 1 346 ? -25.28541 -8.83107  14.03392 1.000 35.59872  ? 343 GLU A CA    1 
ATOM   2789 C  C     . GLU A 1 346 ? -25.10530 -10.04291 14.93279 1.000 37.60870  ? 343 GLU A C     1 
ATOM   2790 O  O     . GLU A 1 346 ? -25.44597 -10.00025 16.12298 1.000 37.43013  ? 343 GLU A O     1 
ATOM   2791 C  CB    . GLU A 1 346 ? -26.52906 -9.00572  13.16551 1.000 41.40926  ? 343 GLU A CB    1 
ATOM   2792 C  CG    . GLU A 1 346 ? -27.80597 -9.23998  13.96423 1.000 43.68901  ? 343 GLU A CG    1 
ATOM   2793 C  CD    . GLU A 1 346 ? -29.03861 -9.29657  13.08097 1.000 51.56015  ? 343 GLU A CD    1 
ATOM   2794 O  OE1   . GLU A 1 346 ? -29.02616 -10.06270 12.09279 1.000 55.62089  ? 343 GLU A OE1   1 
ATOM   2795 O  OE2   . GLU A 1 346 ? -30.01557 -8.57531  13.37147 1.000 59.42548  ? 343 GLU A OE2   1 
ATOM   2796 N  N     . TYR A 1 347 ? -24.55507 -11.12898 14.37882 1.000 36.21778  ? 344 TYR A N     1 
ATOM   2797 C  CA    . TYR A 1 347 ? -24.34674 -12.34497 15.16015 1.000 34.05690  ? 344 TYR A CA    1 
ATOM   2798 C  C     . TYR A 1 347 ? -23.42317 -12.08499 16.34298 1.000 37.54639  ? 344 TYR A C     1 
ATOM   2799 O  O     . TYR A 1 347 ? -23.69475 -12.53536 17.46355 1.000 36.12636  ? 344 TYR A O     1 
ATOM   2800 C  CB    . TYR A 1 347 ? -23.77989 -13.45702 14.27085 1.000 33.54342  ? 344 TYR A CB    1 
ATOM   2801 C  CG    . TYR A 1 347 ? -23.43277 -14.71513 15.04158 1.000 36.56309  ? 344 TYR A CG    1 
ATOM   2802 C  CD1   . TYR A 1 347 ? -24.41803 -15.63197 15.39740 1.000 41.48336  ? 344 TYR A CD1   1 
ATOM   2803 C  CD2   . TYR A 1 347 ? -22.12606 -14.96363 15.45346 1.000 39.93510  ? 344 TYR A CD2   1 
ATOM   2804 C  CE1   . TYR A 1 347 ? -24.10448 -16.77593 16.12321 1.000 38.06817  ? 344 TYR A CE1   1 
ATOM   2805 C  CE2   . TYR A 1 347 ? -21.80440 -16.09628 16.18089 1.000 38.72743  ? 344 TYR A CE2   1 
ATOM   2806 C  CZ    . TYR A 1 347 ? -22.79535 -16.99906 16.51129 1.000 47.64995  ? 344 TYR A CZ    1 
ATOM   2807 O  OH    . TYR A 1 347 ? -22.47044 -18.12784 17.23270 1.000 48.65015  ? 344 TYR A OH    1 
ATOM   2808 N  N     . CYS A 1 348 ? -22.32640 -11.35591 16.11542 1.000 35.31401  ? 345 CYS A N     1 
ATOM   2809 C  CA    . CYS A 1 348 ? -21.38342 -11.08584 17.19438 1.000 28.63927  ? 345 CYS A CA    1 
ATOM   2810 C  C     . CYS A 1 348 ? -21.98781 -10.16166 18.24012 1.000 33.81001  ? 345 CYS A C     1 
ATOM   2811 O  O     . CYS A 1 348 ? -21.75681 -10.34172 19.44296 1.000 33.80683  ? 345 CYS A O     1 
ATOM   2812 C  CB    . CYS A 1 348 ? -20.09623 -10.48544 16.64070 1.000 29.82761  ? 345 CYS A CB    1 
ATOM   2813 S  SG    . CYS A 1 348 ? -19.07187 -11.63391 15.70988 1.000 32.22251  ? 345 CYS A SG    1 
ATOM   2814 N  N     . TRP A 1 349 ? -22.74188 -9.15146  17.80522 1.000 34.00405  ? 346 TRP A N     1 
ATOM   2815 C  CA    . TRP A 1 349 ? -23.46984 -8.32673  18.76198 1.000 36.98852  ? 346 TRP A CA    1 
ATOM   2816 C  C     . TRP A 1 349 ? -24.39021 -9.19027  19.61695 1.000 37.14912  ? 346 TRP A C     1 
ATOM   2817 O  O     . TRP A 1 349 ? -24.36983 -9.11095  20.85020 1.000 35.06169  ? 346 TRP A O     1 
ATOM   2818 C  CB    . TRP A 1 349 ? -24.26310 -7.24071  18.02557 1.000 34.90617  ? 346 TRP A CB    1 
ATOM   2819 C  CG    . TRP A 1 349 ? -25.13295 -6.41664  18.93739 1.000 34.39592  ? 346 TRP A CG    1 
ATOM   2820 C  CD1   . TRP A 1 349 ? -26.44162 -6.65572  19.26257 1.000 36.14453  ? 346 TRP A CD1   1 
ATOM   2821 C  CD2   . TRP A 1 349 ? -24.74919 -5.23972  19.66273 1.000 35.15602  ? 346 TRP A CD2   1 
ATOM   2822 N  NE1   . TRP A 1 349 ? -26.89577 -5.69249  20.13501 1.000 38.52963  ? 346 TRP A NE1   1 
ATOM   2823 C  CE2   . TRP A 1 349 ? -25.87780 -4.81169  20.39556 1.000 35.63233  ? 346 TRP A CE2   1 
ATOM   2824 C  CE3   . TRP A 1 349 ? -23.56541 -4.49620  19.75236 1.000 33.86201  ? 346 TRP A CE3   1 
ATOM   2825 C  CZ2   . TRP A 1 349 ? -25.85656 -3.67408  21.20719 1.000 35.69960  ? 346 TRP A CZ2   1 
ATOM   2826 C  CZ3   . TRP A 1 349 ? -23.54372 -3.37355  20.56702 1.000 34.77097  ? 346 TRP A CZ3   1 
ATOM   2827 C  CH2   . TRP A 1 349 ? -24.68381 -2.97292  21.28249 1.000 35.61955  ? 346 TRP A CH2   1 
ATOM   2828 N  N     . ASP A 1 350 ? -25.17652 -10.05700 18.97245 1.000 35.35999  ? 347 ASP A N     1 
ATOM   2829 C  CA    . ASP A 1 350 ? -26.14151 -10.87291 19.69895 1.000 37.57765  ? 347 ASP A CA    1 
ATOM   2830 C  C     . ASP A 1 350 ? -25.46609 -11.88919 20.61662 1.000 43.92157  ? 347 ASP A C     1 
ATOM   2831 O  O     . ASP A 1 350 ? -26.01249 -12.20948 21.67867 1.000 48.24368  ? 347 ASP A O     1 
ATOM   2832 C  CB    . ASP A 1 350 ? -27.06522 -11.59338 18.71547 1.000 38.41579  ? 347 ASP A CB    1 
ATOM   2833 C  CG    . ASP A 1 350 ? -28.05507 -10.65747 18.03858 1.000 44.99738  ? 347 ASP A CG    1 
ATOM   2834 O  OD1   . ASP A 1 350 ? -28.24679 -9.51669  18.51152 1.000 41.87983  ? 347 ASP A OD1   1 
ATOM   2835 O  OD2   . ASP A 1 350 ? -28.64771 -11.07172 17.02610 1.000 44.23122  ? 347 ASP A OD2   1 
ATOM   2836 N  N     . THR A 1 351 ? -24.28484 -12.39362 20.24258 1.000 37.39379  ? 348 THR A N     1 
ATOM   2837 C  CA    . THR A 1 351 ? -23.65301 -13.51875 20.93398 1.000 35.39798  ? 348 THR A CA    1 
ATOM   2838 C  C     . THR A 1 351 ? -22.59550 -13.10978 21.95280 1.000 34.93476  ? 348 THR A C     1 
ATOM   2839 O  O     . THR A 1 351 ? -22.56056 -13.66653 23.05591 1.000 37.93947  ? 348 THR A O     1 
ATOM   2840 C  CB    . THR A 1 351 ? -23.00534 -14.47855 19.92261 1.000 35.15233  ? 348 THR A CB    1 
ATOM   2841 O  OG1   . THR A 1 351 ? -23.95797 -14.85775 18.91713 1.000 38.91114  ? 348 THR A OG1   1 
ATOM   2842 C  CG2   . THR A 1 351 ? -22.47991 -15.72237 20.62050 1.000 37.32132  ? 348 THR A CG2   1 
ATOM   2843 N  N     . PHE A 1 352 ? -21.71282 -12.17001 21.60920 1.000 32.62150  ? 349 PHE A N     1 
ATOM   2844 C  CA    . PHE A 1 352 ? -20.51977 -11.90536 22.40051 1.000 31.54496  ? 349 PHE A CA    1 
ATOM   2845 C  C     . PHE A 1 352 ? -20.55609 -10.59307 23.16579 1.000 35.48672  ? 349 PHE A C     1 
ATOM   2846 O  O     . PHE A 1 352 ? -19.63322 -10.32855 23.94479 1.000 33.50027  ? 349 PHE A O     1 
ATOM   2847 C  CB    . PHE A 1 352 ? -19.27279 -11.92091 21.49917 1.000 28.11801  ? 349 PHE A CB    1 
ATOM   2848 C  CG    . PHE A 1 352 ? -19.10422 -13.19630 20.70301 1.000 29.13179  ? 349 PHE A CG    1 
ATOM   2849 C  CD1   . PHE A 1 352 ? -18.58268 -14.33987 21.29666 1.000 31.63475  ? 349 PHE A CD1   1 
ATOM   2850 C  CD2   . PHE A 1 352 ? -19.44888 -13.24668 19.36447 1.000 34.50651  ? 349 PHE A CD2   1 
ATOM   2851 C  CE1   . PHE A 1 352 ? -18.41849 -15.51580 20.56642 1.000 28.99256  ? 349 PHE A CE1   1 
ATOM   2852 C  CE2   . PHE A 1 352 ? -19.28764 -14.41929 18.62724 1.000 38.95055  ? 349 PHE A CE2   1 
ATOM   2853 C  CZ    . PHE A 1 352 ? -18.77215 -15.55594 19.23448 1.000 37.23065  ? 349 PHE A CZ    1 
ATOM   2854 N  N     . VAL A 1 353 ? -21.58721 -9.77591  22.98361 1.000 33.18480  ? 350 VAL A N     1 
ATOM   2855 C  CA    . VAL A 1 353 ? -21.60629 -8.41287  23.49478 1.000 32.04190  ? 350 VAL A CA    1 
ATOM   2856 C  C     . VAL A 1 353 ? -22.61224 -8.31389  24.63303 1.000 34.65399  ? 350 VAL A C     1 
ATOM   2857 O  O     . VAL A 1 353 ? -23.68947 -8.91882  24.58569 1.000 35.39104  ? 350 VAL A O     1 
ATOM   2858 C  CB    . VAL A 1 353 ? -21.92988 -7.40373  22.37166 1.000 34.49464  ? 350 VAL A CB    1 
ATOM   2859 C  CG1   . VAL A 1 353 ? -22.06830 -5.99983  22.93243 1.000 32.94929  ? 350 VAL A CG1   1 
ATOM   2860 C  CG2   . VAL A 1 353 ? -20.83744 -7.43656  21.30488 1.000 27.92559  ? 350 VAL A CG2   1 
ATOM   2861 N  N     . ASP A 1 354 ? -22.24911 -7.54962  25.66199 1.000 36.91872  ? 351 ASP A N     1 
ATOM   2862 C  CA    . ASP A 1 354 ? -23.13499 -7.23293  26.78206 1.000 39.17406  ? 351 ASP A CA    1 
ATOM   2863 C  C     . ASP A 1 354 ? -24.16414 -6.20232  26.31645 1.000 41.30330  ? 351 ASP A C     1 
ATOM   2864 O  O     . ASP A 1 354 ? -24.09790 -5.01321  26.63696 1.000 44.54052  ? 351 ASP A O     1 
ATOM   2865 C  CB    . ASP A 1 354 ? -22.31489 -6.72376  27.96020 1.000 36.71162  ? 351 ASP A CB    1 
ATOM   2866 C  CG    . ASP A 1 354 ? -23.11475 -6.64062  29.24033 1.000 46.36945  ? 351 ASP A CG    1 
ATOM   2867 O  OD1   . ASP A 1 354 ? -24.21001 -7.23736  29.30847 1.000 45.74034  ? 351 ASP A OD1   1 
ATOM   2868 O  OD2   . ASP A 1 354 ? -22.63252 -5.97737  30.17938 1.000 49.71884  ? 351 ASP A OD2   1 
ATOM   2869 N  N     . ARG A 1 355 ? -25.14735 -6.67748  25.54888 1.000 42.16636  ? 352 ARG A N     1 
ATOM   2870 C  CA    . ARG A 1 355 ? -26.09684 -5.77542  24.90587 1.000 43.97726  ? 352 ARG A CA    1 
ATOM   2871 C  C     . ARG A 1 355 ? -27.26048 -5.37791  25.80235 1.000 53.59652  ? 352 ARG A C     1 
ATOM   2872 O  O     . ARG A 1 355 ? -27.97628 -4.43018  25.46109 1.000 50.13639  ? 352 ARG A O     1 
ATOM   2873 C  CB    . ARG A 1 355 ? -26.65243 -6.40772  23.62975 1.000 40.10146  ? 352 ARG A CB    1 
ATOM   2874 C  CG    . ARG A 1 355 ? -27.00103 -7.86637  23.76382 1.000 44.28089  ? 352 ARG A CG    1 
ATOM   2875 C  CD    . ARG A 1 355 ? -27.27179 -8.48988  22.41477 1.000 37.24926  ? 352 ARG A CD    1 
ATOM   2876 N  NE    . ARG A 1 355 ? -28.12908 -9.66215  22.51415 1.000 44.20822  ? 352 ARG A NE    1 
ATOM   2877 C  CZ    . ARG A 1 355 ? -29.44729 -9.64995  22.36740 1.000 53.33599  ? 352 ARG A CZ    1 
ATOM   2878 N  NH1   . ARG A 1 355 ? -30.10275 -8.53537  22.08097 1.000 60.87123  ? 352 ARG A NH1   1 
ATOM   2879 N  NH2   . ARG A 1 355 ? -30.12333 -10.78904 22.49239 1.000 55.04137  ? 352 ARG A NH2   1 
ATOM   2880 N  N     . GLN A 1 356 ? -27.46982 -6.07215  26.92071 1.000 50.96030  ? 353 GLN A N     1 
ATOM   2881 C  CA    . GLN A 1 356 ? -28.61648 -5.83220  27.79767 1.000 52.76499  ? 353 GLN A CA    1 
ATOM   2882 C  C     . GLN A 1 356 ? -29.91693 -5.80932  26.99627 1.000 53.67190  ? 353 GLN A C     1 
ATOM   2883 O  O     . GLN A 1 356 ? -30.69651 -4.85486  27.04919 1.000 56.91217  ? 353 GLN A O     1 
ATOM   2884 C  CB    . GLN A 1 356 ? -28.43805 -4.53945  28.59868 1.000 51.69650  ? 353 GLN A CB    1 
ATOM   2885 C  CG    . GLN A 1 356 ? -27.10826 -4.43446  29.33073 1.000 57.52051  ? 353 GLN A CG    1 
ATOM   2886 C  CD    . GLN A 1 356 ? -27.11475 -5.19882  30.64179 1.000 73.26881  ? 353 GLN A CD    1 
ATOM   2887 O  OE1   . GLN A 1 356 ? -26.39887 -6.19154  30.80391 1.000 72.29548  ? 353 GLN A OE1   1 
ATOM   2888 N  NE2   . GLN A 1 356 ? -27.93002 -4.73866  31.58868 1.000 75.86031  ? 353 GLN A NE2   1 
ATOM   2889 N  N     . GLY A 1 357 ? -30.12674 -6.86861  26.21078 1.000 55.53417  ? 354 GLY A N     1 
ATOM   2890 C  CA    . GLY A 1 357 ? -31.32362 -7.02273  25.41155 1.000 59.08085  ? 354 GLY A CA    1 
ATOM   2891 C  C     . GLY A 1 357 ? -31.44552 -6.11361  24.20337 1.000 58.10652  ? 354 GLY A C     1 
ATOM   2892 O  O     . GLY A 1 357 ? -32.29329 -6.37511  23.34113 1.000 61.10924  ? 354 GLY A O     1 
ATOM   2893 N  N     . ARG A 1 358 ? -30.63503 -5.05929  24.10402 1.000 54.62074  ? 355 ARG A N     1 
ATOM   2894 C  CA    . ARG A 1 358 ? -30.75648 -4.12354  22.99082 1.000 55.50795  ? 355 ARG A CA    1 
ATOM   2895 C  C     . ARG A 1 358 ? -30.37278 -4.80063  21.67509 1.000 48.43607  ? 355 ARG A C     1 
ATOM   2896 O  O     . ARG A 1 358 ? -29.42779 -5.59299  21.63734 1.000 50.69693  ? 355 ARG A O     1 
ATOM   2897 C  CB    . ARG A 1 358 ? -29.86862 -2.89912  23.22365 1.000 49.35496  ? 355 ARG A CB    1 
ATOM   2898 C  CG    . ARG A 1 358 ? -30.33471 -2.00155  24.35331 1.000 58.21974  ? 355 ARG A CG    1 
ATOM   2899 C  CD    . ARG A 1 358 ? -29.92324 -0.55318  24.10897 1.000 65.04026  ? 355 ARG A CD    1 
ATOM   2900 N  NE    . ARG A 1 358 ? -30.33511 0.31858   25.20274 1.000 69.84845  ? 355 ARG A NE    1 
ATOM   2901 C  CZ    . ARG A 1 358 ? -31.50473 0.94231   25.26238 1.000 65.07473  ? 355 ARG A CZ    1 
ATOM   2902 N  NH1   . ARG A 1 358 ? -32.39958 0.82845   24.29377 1.000 61.00642  ? 355 ARG A NH1   1 
ATOM   2903 N  NH2   . ARG A 1 358 ? -31.78402 1.69834   26.32128 1.000 65.77112  ? 355 ARG A NH2   1 
ATOM   2904 N  N     . PRO A 1 359 ? -31.07342 -4.50427  20.58307 1.000 55.80610  ? 356 PRO A N     1 
ATOM   2905 C  CA    . PRO A 1 359 ? -30.75215 -5.13036  19.29742 1.000 50.23686  ? 356 PRO A CA    1 
ATOM   2906 C  C     . PRO A 1 359 ? -29.56060 -4.45781  18.62671 1.000 43.63642  ? 356 PRO A C     1 
ATOM   2907 O  O     . PRO A 1 359 ? -29.09825 -3.38941  19.02914 1.000 42.82909  ? 356 PRO A O     1 
ATOM   2908 C  CB    . PRO A 1 359 ? -32.02809 -4.92090  18.48021 1.000 45.09574  ? 356 PRO A CB    1 
ATOM   2909 C  CG    . PRO A 1 359 ? -32.55062 -3.61907  18.98328 1.000 52.69025  ? 356 PRO A CG    1 
ATOM   2910 C  CD    . PRO A 1 359 ? -32.19736 -3.55755  20.46264 1.000 52.59688  ? 356 PRO A CD    1 
ATOM   2911 N  N     . PHE A 1 360 ? -29.06796 -5.11631  17.57877 1.000 38.68019  ? 357 PHE A N     1 
ATOM   2912 C  CA    . PHE A 1 360 ? -27.92996 -4.60199  16.82579 1.000 43.51659  ? 357 PHE A CA    1 
ATOM   2913 C  C     . PHE A 1 360 ? -28.34111 -3.35802  16.04585 1.000 43.38799  ? 357 PHE A C     1 
ATOM   2914 O  O     . PHE A 1 360 ? -29.26789 -3.40534  15.23382 1.000 46.07500  ? 357 PHE A O     1 
ATOM   2915 C  CB    . PHE A 1 360 ? -27.39375 -5.66677  15.87187 1.000 44.04487  ? 357 PHE A CB    1 
ATOM   2916 C  CG    . PHE A 1 360 ? -26.26099 -5.18588  15.00269 1.000 39.80033  ? 357 PHE A CG    1 
ATOM   2917 C  CD1   . PHE A 1 360 ? -25.12115 -4.63148  15.57088 1.000 39.35808  ? 357 PHE A CD1   1 
ATOM   2918 C  CD2   . PHE A 1 360 ? -26.34415 -5.27083  13.62193 1.000 38.48410  ? 357 PHE A CD2   1 
ATOM   2919 C  CE1   . PHE A 1 360 ? -24.07629 -4.18600  14.77953 1.000 38.99433  ? 357 PHE A CE1   1 
ATOM   2920 C  CE2   . PHE A 1 360 ? -25.30366 -4.82355  12.81949 1.000 40.13797  ? 357 PHE A CE2   1 
ATOM   2921 C  CZ    . PHE A 1 360 ? -24.16988 -4.27846  13.39927 1.000 37.09093  ? 357 PHE A CZ    1 
ATOM   2922 N  N     . GLN A 1 361 ? -27.64632 -2.25097  16.28794 1.000 42.49539  ? 358 GLN A N     1 
ATOM   2923 C  CA    . GLN A 1 361 ? -27.88040 -0.99835  15.57911 1.000 45.63851  ? 358 GLN A CA    1 
ATOM   2924 C  C     . GLN A 1 361 ? -26.71447 -0.75494  14.63106 1.000 40.52059  ? 358 GLN A C     1 
ATOM   2925 O  O     . GLN A 1 361 ? -25.64041 -0.31643  15.06958 1.000 41.29418  ? 358 GLN A O     1 
ATOM   2926 C  CB    . GLN A 1 361 ? -28.02559 0.15992   16.56960 1.000 45.93882  ? 358 GLN A CB    1 
ATOM   2927 C  CG    . GLN A 1 361 ? -28.35654 1.50093   15.92031 1.000 60.88937  ? 358 GLN A CG    1 
ATOM   2928 C  CD    . GLN A 1 361 ? -29.58491 1.43040   15.02332 1.000 69.74058  ? 358 GLN A CD    1 
ATOM   2929 O  OE1   . GLN A 1 361 ? -29.47427 1.43680   13.79568 1.000 69.25919  ? 358 GLN A OE1   1 
ATOM   2930 N  NE2   . GLN A 1 361 ? -30.76359 1.35432   15.63598 1.000 71.11696  ? 358 GLN A NE2   1 
ATOM   2931 N  N     . PRO A 1 362 ? -26.86381 -1.02687  13.33484 1.000 45.19013  ? 359 PRO A N     1 
ATOM   2932 C  CA    . PRO A 1 362 ? -25.71111 -0.94498  12.42808 1.000 38.93563  ? 359 PRO A CA    1 
ATOM   2933 C  C     . PRO A 1 362 ? -25.22326 0.48500   12.26028 1.000 45.35715  ? 359 PRO A C     1 
ATOM   2934 O  O     . PRO A 1 362 ? -26.01170 1.43143   12.23813 1.000 40.43980  ? 359 PRO A O     1 
ATOM   2935 C  CB    . PRO A 1 362 ? -26.25649 -1.50639  11.10909 1.000 45.16427  ? 359 PRO A CB    1 
ATOM   2936 C  CG    . PRO A 1 362 ? -27.73216 -1.25012  11.17801 1.000 49.22010  ? 359 PRO A CG    1 
ATOM   2937 C  CD    . PRO A 1 362 ? -28.09988 -1.41009  12.63282 1.000 45.18180  ? 359 PRO A CD    1 
ATOM   2938 N  N     . TRP A 1 363 ? -23.90584 0.63468   12.15327 1.000 44.08298  ? 360 TRP A N     1 
ATOM   2939 C  CA    . TRP A 1 363 ? -23.31121 1.93549   11.89072 1.000 43.02958  ? 360 TRP A CA    1 
ATOM   2940 C  C     . TRP A 1 363 ? -23.51896 2.32744   10.42970 1.000 43.89377  ? 360 TRP A C     1 
ATOM   2941 O  O     . TRP A 1 363 ? -23.79360 1.48608   9.56854  1.000 39.40074  ? 360 TRP A O     1 
ATOM   2942 C  CB    . TRP A 1 363 ? -21.82013 1.91213   12.21969 1.000 41.56749  ? 360 TRP A CB    1 
ATOM   2943 C  CG    . TRP A 1 363 ? -21.13284 0.68809   11.69078 1.000 36.05238  ? 360 TRP A CG    1 
ATOM   2944 C  CD1   . TRP A 1 363 ? -20.63275 0.50899   10.43303 1.000 36.42763  ? 360 TRP A CD1   1 
ATOM   2945 C  CD2   . TRP A 1 363 ? -20.87932 -0.53316  12.40246 1.000 39.02281  ? 360 TRP A CD2   1 
ATOM   2946 N  NE1   . TRP A 1 363 ? -20.07733 -0.74693  10.31992 1.000 35.28626  ? 360 TRP A NE1   1 
ATOM   2947 C  CE2   . TRP A 1 363 ? -20.21835 -1.40633  11.51285 1.000 32.48886  ? 360 TRP A CE2   1 
ATOM   2948 C  CE3   . TRP A 1 363 ? -21.14365 -0.96987  13.70380 1.000 32.98292  ? 360 TRP A CE3   1 
ATOM   2949 C  CZ2   . TRP A 1 363 ? -19.82046 -2.69428  11.88252 1.000 31.21956  ? 360 TRP A CZ2   1 
ATOM   2950 C  CZ3   . TRP A 1 363 ? -20.74563 -2.25008  14.07131 1.000 33.86604  ? 360 TRP A CZ3   1 
ATOM   2951 C  CH2   . TRP A 1 363 ? -20.09124 -3.09439  13.16356 1.000 36.61320  ? 360 TRP A CH2   1 
ATOM   2952 N  N     . ASP A 1 364 ? -23.38373 3.62778   10.15672 1.000 44.46210  ? 361 ASP A N     1 
ATOM   2953 C  CA    . ASP A 1 364 ? -23.54101 4.13177   8.79733  1.000 46.34354  ? 361 ASP A CA    1 
ATOM   2954 C  C     . ASP A 1 364 ? -22.55082 3.47015   7.84535  1.000 38.35737  ? 361 ASP A C     1 
ATOM   2955 O  O     . ASP A 1 364 ? -21.37080 3.29997   8.16689  1.000 38.20857  ? 361 ASP A O     1 
ATOM   2956 C  CB    . ASP A 1 364 ? -23.34510 5.65467   8.75397  1.000 54.60410  ? 361 ASP A CB    1 
ATOM   2957 C  CG    . ASP A 1 364 ? -24.47536 6.42219   9.42629  1.000 60.11169  ? 361 ASP A CG    1 
ATOM   2958 O  OD1   . ASP A 1 364 ? -25.62076 5.92070   9.43989  1.000 65.83050  ? 361 ASP A OD1   1 
ATOM   2959 O  OD2   . ASP A 1 364 ? -24.21948 7.53990   9.92544  1.000 63.82211  ? 361 ASP A OD2   1 
ATOM   2960 N  N     . GLY A 1 365 ? -23.04219 3.11349   6.65958  1.000 38.69038  ? 362 GLY A N     1 
ATOM   2961 C  CA    . GLY A 1 365 ? -22.20303 2.57890   5.60371  1.000 37.87641  ? 362 GLY A CA    1 
ATOM   2962 C  C     . GLY A 1 365 ? -21.73193 1.15369   5.78468  1.000 41.52806  ? 362 GLY A C     1 
ATOM   2963 O  O     . GLY A 1 365 ? -20.81219 0.73232   5.07657  1.000 35.00135  ? 362 GLY A O     1 
ATOM   2964 N  N     . LEU A 1 366 ? -22.33743 0.39411   6.70505  1.000 39.14949  ? 363 LEU A N     1 
ATOM   2965 C  CA    . LEU A 1 366 ? -21.86000 -0.95799  6.99983  1.000 37.38056  ? 363 LEU A CA    1 
ATOM   2966 C  C     . LEU A 1 366 ? -21.82548 -1.82342  5.74280  1.000 36.26234  ? 363 LEU A C     1 
ATOM   2967 O  O     . LEU A 1 366 ? -20.81261 -2.46766  5.44610  1.000 35.16275  ? 363 LEU A O     1 
ATOM   2968 C  CB    . LEU A 1 366 ? -22.73444 -1.60213  8.08385  1.000 32.36042  ? 363 LEU A CB    1 
ATOM   2969 C  CG    . LEU A 1 366 ? -22.30580 -2.96712  8.66432  1.000 35.59169  ? 363 LEU A CG    1 
ATOM   2970 C  CD1   . LEU A 1 366 ? -22.95292 -3.22285  10.02153 1.000 30.91375  ? 363 LEU A CD1   1 
ATOM   2971 C  CD2   . LEU A 1 366 ? -22.63931 -4.12836  7.73516  1.000 38.53193  ? 363 LEU A CD2   1 
ATOM   2972 N  N     . ASP A 1 367 ? -22.92499 -1.85485  4.99061  1.000 38.28464  ? 364 ASP A N     1 
ATOM   2973 C  CA    . ASP A 1 367 ? -22.96428 -2.70900  3.80737  1.000 41.38653  ? 364 ASP A CA    1 
ATOM   2974 C  C     . ASP A 1 367 ? -21.99711 -2.22179  2.73293  1.000 36.59711  ? 364 ASP A C     1 
ATOM   2975 O  O     . ASP A 1 367 ? -21.31296 -3.03076  2.09591  1.000 33.61790  ? 364 ASP A O     1 
ATOM   2976 C  CB    . ASP A 1 367 ? -24.38778 -2.78588  3.25672  1.000 50.30182  ? 364 ASP A CB    1 
ATOM   2977 C  CG    . ASP A 1 367 ? -25.36819 -3.35861  4.26734  1.000 58.85220  ? 364 ASP A CG    1 
ATOM   2978 O  OD1   . ASP A 1 367 ? -25.22689 -4.54823  4.62712  1.000 54.24122  ? 364 ASP A OD1   1 
ATOM   2979 O  OD2   . ASP A 1 367 ? -26.30037 -2.63206  4.67751  1.000 65.93379  ? 364 ASP A OD2   1 
ATOM   2980 N  N     . GLU A 1 368 ? -21.90804 -0.90423  2.52779  1.000 35.11533  ? 365 GLU A N     1 
ATOM   2981 C  CA    . GLU A 1 368 ? -21.01670 -0.39273  1.49115  1.000 41.84558  ? 365 GLU A CA    1 
ATOM   2982 C  C     . GLU A 1 368 ? -19.55494 -0.68825  1.81827  1.000 35.80656  ? 365 GLU A C     1 
ATOM   2983 O  O     . GLU A 1 368 ? -18.79239 -1.12434  0.94431  1.000 36.93037  ? 365 GLU A O     1 
ATOM   2984 C  CB    . GLU A 1 368 ? -21.24826 1.10633   1.29536  1.000 40.41174  ? 365 GLU A CB    1 
ATOM   2985 C  CG    . GLU A 1 368 ? -20.17142 1.79121   0.48496  1.000 50.34316  ? 365 GLU A CG    1 
ATOM   2986 C  CD    . GLU A 1 368 ? -20.48005 3.25179   0.19325  1.000 50.66923  ? 365 GLU A CD    1 
ATOM   2987 O  OE1   . GLU A 1 368 ? -21.37134 3.83068   0.85762  1.000 50.71197  ? 365 GLU A OE1   1 
ATOM   2988 O  OE2   . GLU A 1 368 ? -19.81533 3.81670   -0.69998 1.000 42.31784  ? 365 GLU A OE2   1 
ATOM   2989 N  N     . HIS A 1 369 ? -19.14788 -0.48148  3.07189  1.000 31.44515  ? 366 HIS A N     1 
ATOM   2990 C  CA    . HIS A 1 369 ? -17.77153 -0.79417  3.45142  1.000 32.12030  ? 366 HIS A CA    1 
ATOM   2991 C  C     . HIS A 1 369 ? -17.48579 -2.29756  3.33863  1.000 31.88512  ? 366 HIS A C     1 
ATOM   2992 O  O     . HIS A 1 369 ? -16.40744 -2.69273  2.87792  1.000 28.60606  ? 366 HIS A O     1 
ATOM   2993 C  CB    . HIS A 1 369 ? -17.48558 -0.28984  4.87057  1.000 31.75285  ? 366 HIS A CB    1 
ATOM   2994 C  CG    . HIS A 1 369 ? -17.62078 1.19687   5.01976  1.000 30.49051  ? 366 HIS A CG    1 
ATOM   2995 N  ND1   . HIS A 1 369 ? -17.06652 2.09127   4.12594  1.000 33.30000  ? 366 HIS A ND1   1 
ATOM   2996 C  CD2   . HIS A 1 369 ? -18.22587 1.94481   5.97212  1.000 31.17556  ? 366 HIS A CD2   1 
ATOM   2997 C  CE1   . HIS A 1 369 ? -17.34493 3.32626   4.50967  1.000 33.25777  ? 366 HIS A CE1   1 
ATOM   2998 N  NE2   . HIS A 1 369 ? -18.04810 3.26541   5.62646  1.000 34.35079  ? 366 HIS A NE2   1 
ATOM   2999 N  N     . SER A 1 370 ? -18.42528 -3.14961  3.76803  1.000 28.85250  ? 367 SER A N     1 
ATOM   3000 C  CA    . SER A 1 370 ? -18.24621 -4.59920  3.59290  1.000 35.16937  ? 367 SER A CA    1 
ATOM   3001 C  C     . SER A 1 370 ? -18.07360 -4.97054  2.12070  1.000 33.10026  ? 367 SER A C     1 
ATOM   3002 O  O     . SER A 1 370 ? -17.26712 -5.84343  1.77870  1.000 34.43659  ? 367 SER A O     1 
ATOM   3003 C  CB    . SER A 1 370 ? -19.43336 -5.37089  4.17407  1.000 32.67750  ? 367 SER A CB    1 
ATOM   3004 O  OG    . SER A 1 370 ? -19.54240 -5.19243  5.57557  1.000 44.50341  ? 367 SER A OG    1 
ATOM   3005 N  N     . GLN A 1 371 ? -18.82992 -4.32573  1.23755  1.000 33.31812  ? 368 GLN A N     1 
ATOM   3006 C  CA    . GLN A 1 371 ? -18.70198 -4.61433  -0.18580 1.000 35.39714  ? 368 GLN A CA    1 
ATOM   3007 C  C     . GLN A 1 371 ? -17.32287 -4.22679  -0.70409 1.000 36.99581  ? 368 GLN A C     1 
ATOM   3008 O  O     . GLN A 1 371 ? -16.67616 -4.99931  -1.42071 1.000 34.67317  ? 368 GLN A O     1 
ATOM   3009 C  CB    . GLN A 1 371 ? -19.79480 -3.88840  -0.96397 1.000 42.16722  ? 368 GLN A CB    1 
ATOM   3010 C  CG    . GLN A 1 371 ? -21.11612 -4.60135  -0.92609 1.000 50.21983  ? 368 GLN A CG    1 
ATOM   3011 C  CD    . GLN A 1 371 ? -22.12519 -4.00662  -1.88249 1.000 63.01081  ? 368 GLN A CD    1 
ATOM   3012 O  OE1   . GLN A 1 371 ? -21.76907 -3.29608  -2.82505 1.000 65.52021  ? 368 GLN A OE1   1 
ATOM   3013 N  NE2   . GLN A 1 371 ? -23.39664 -4.30847  -1.65369 1.000 73.75409  ? 368 GLN A NE2   1 
ATOM   3014 N  N     . ALA A 1 372 ? -16.86388 -3.02210  -0.36966 1.000 33.98383  ? 369 ALA A N     1 
ATOM   3015 C  CA    . ALA A 1 372 ? -15.55532 -2.58126  -0.83431 1.000 31.06891  ? 369 ALA A CA    1 
ATOM   3016 C  C     . ALA A 1 372 ? -14.45551 -3.48399  -0.29711 1.000 33.82429  ? 369 ALA A C     1 
ATOM   3017 O  O     . ALA A 1 372 ? -13.57295 -3.91304  -1.04786 1.000 34.62888  ? 369 ALA A O     1 
ATOM   3018 C  CB    . ALA A 1 372 ? -15.31660 -1.12651  -0.42681 1.000 32.07469  ? 369 ALA A CB    1 
ATOM   3019 N  N     . LEU A 1 373 ? -14.49795 -3.78853  1.00906  1.000 29.62550  ? 370 LEU A N     1 
ATOM   3020 C  CA    . LEU A 1 373 ? -13.51623 -4.68981  1.60731  1.000 30.48304  ? 370 LEU A CA    1 
ATOM   3021 C  C     . LEU A 1 373 ? -13.58185 -6.09378  1.01484  1.000 33.51600  ? 370 LEU A C     1 
ATOM   3022 O  O     . LEU A 1 373 ? -12.54587 -6.75207  0.85718  1.000 31.13453  ? 370 LEU A O     1 
ATOM   3023 C  CB    . LEU A 1 373 ? -13.71712 -4.75888  3.12352  1.000 29.53861  ? 370 LEU A CB    1 
ATOM   3024 C  CG    . LEU A 1 373 ? -13.29664 -3.49068  3.85413  1.000 33.69010  ? 370 LEU A CG    1 
ATOM   3025 C  CD1   . LEU A 1 373 ? -13.83714 -3.48492  5.29168  1.000 29.25967  ? 370 LEU A CD1   1 
ATOM   3026 C  CD2   . LEU A 1 373 ? -11.77816 -3.38539  3.81682  1.000 30.51162  ? 370 LEU A CD2   1 
ATOM   3027 N  N     . SER A 1 374 ? -14.78089 -6.59540  0.71911  1.000 32.31929  ? 371 SER A N     1 
ATOM   3028 C  CA    . SER A 1 374 ? -14.85813 -7.92302  0.11485  1.000 32.94488  ? 371 SER A CA    1 
ATOM   3029 C  C     . SER A 1 374 ? -14.19002 -7.93915  -1.25534 1.000 41.18542  ? 371 SER A C     1 
ATOM   3030 O  O     . SER A 1 374 ? -13.51232 -8.91070  -1.61053 1.000 34.85551  ? 371 SER A O     1 
ATOM   3031 C  CB    . SER A 1 374 ? -16.31223 -8.38953  0.01848  1.000 36.23664  ? 371 SER A CB    1 
ATOM   3032 O  OG    . SER A 1 374 ? -16.86745 -8.57945  1.31277  1.000 39.39574  ? 371 SER A OG    1 
ATOM   3033 N  N     . GLY A 1 375 ? -14.35711 -6.86433  -2.03163 1.000 39.08050  ? 372 GLY A N     1 
ATOM   3034 C  CA    . GLY A 1 375 ? -13.71010 -6.79110  -3.33513 1.000 39.85773  ? 372 GLY A CA    1 
ATOM   3035 C  C     . GLY A 1 375 ? -12.20133 -6.67591  -3.22585 1.000 38.83869  ? 372 GLY A C     1 
ATOM   3036 O  O     . GLY A 1 375 ? -11.46389 -7.21192  -4.05692 1.000 35.36503  ? 372 GLY A O     1 
ATOM   3037 N  N     . ARG A 1 376 ? -11.72093 -5.98215  -2.19487 1.000 37.02812  ? 373 ARG A N     1 
ATOM   3038 C  CA    . ARG A 1 376 ? -10.28628 -5.93366  -1.93456 1.000 31.95854  ? 373 ARG A CA    1 
ATOM   3039 C  C     . ARG A 1 376 ? -9.75342  -7.30144  -1.50939 1.000 42.15509  ? 373 ARG A C     1 
ATOM   3040 O  O     . ARG A 1 376 ? -8.69917  -7.73877  -1.98730 1.000 37.25202  ? 373 ARG A O     1 
ATOM   3041 C  CB    . ARG A 1 376 ? -9.99824  -4.87282  -0.87227 1.000 33.67053  ? 373 ARG A CB    1 
ATOM   3042 C  CG    . ARG A 1 376 ? -8.54312  -4.73227  -0.46739 1.000 41.86812  ? 373 ARG A CG    1 
ATOM   3043 C  CD    . ARG A 1 376 ? -8.37620  -3.52639  0.47408  1.000 55.90142  ? 373 ARG A CD    1 
ATOM   3044 N  NE    . ARG A 1 376 ? -7.06981  -3.48372  1.12265  1.000 57.56909  ? 373 ARG A NE    1 
ATOM   3045 C  CZ    . ARG A 1 376 ? -6.80557  -2.80857  2.23521  1.000 56.40232  ? 373 ARG A CZ    1 
ATOM   3046 N  NH1   . ARG A 1 376 ? -7.72349  -2.04918  2.82070  1.000 46.94582  ? 373 ARG A NH1   1 
ATOM   3047 N  NH2   . ARG A 1 376 ? -5.58802  -2.88940  2.76959  1.000 50.41312  ? 373 ARG A NH2   1 
ATOM   3048 N  N     . LEU A 1 377 ? -10.46397 -7.99332  -0.61477 1.000 36.95674  ? 374 LEU A N     1 
ATOM   3049 C  CA    . LEU A 1 377 ? -10.04929 -9.34498  -0.24112 1.000 34.67238  ? 374 LEU A CA    1 
ATOM   3050 C  C     . LEU A 1 377 ? -10.02934 -10.26668 -1.46028 1.000 39.23167  ? 374 LEU A C     1 
ATOM   3051 O  O     . LEU A 1 377 ? -9.05769  -10.99675 -1.68121 1.000 36.93935  ? 374 LEU A O     1 
ATOM   3052 C  CB    . LEU A 1 377 ? -10.96845 -9.90960  0.84279  1.000 33.47910  ? 374 LEU A CB    1 
ATOM   3053 C  CG    . LEU A 1 377 ? -10.62145 -11.35244 1.27764  1.000 34.64457  ? 374 LEU A CG    1 
ATOM   3054 C  CD1   . LEU A 1 377 ? -9.20062  -11.45774 1.82924  1.000 28.35463  ? 374 LEU A CD1   1 
ATOM   3055 C  CD2   . LEU A 1 377 ? -11.61074 -11.88797 2.28573  1.000 32.25963  ? 374 LEU A CD2   1 
ATOM   3056 N  N     . ARG A 1 378 ? -11.09947 -10.23911 -2.26449 1.000 37.25101  ? 375 ARG A N     1 
ATOM   3057 C  CA    . ARG A 1 378 ? -11.14698 -11.02541 -3.49987 1.000 39.71586  ? 375 ARG A CA    1 
ATOM   3058 C  C     . ARG A 1 378 ? -9.91835  -10.78926 -4.37114 1.000 42.70483  ? 375 ARG A C     1 
ATOM   3059 O  O     . ARG A 1 378 ? -9.33619  -11.73985 -4.90895 1.000 48.28003  ? 375 ARG A O     1 
ATOM   3060 C  CB    . ARG A 1 378 ? -12.41502 -10.68808 -4.28830 1.000 40.61118  ? 375 ARG A CB    1 
ATOM   3061 C  CG    . ARG A 1 378 ? -13.01060 -11.84694 -5.09244 1.000 50.86120  ? 375 ARG A CG    1 
ATOM   3062 C  CD    . ARG A 1 378 ? -14.31168 -11.42794 -5.78627 1.000 60.86020  ? 375 ARG A CD    1 
ATOM   3063 N  NE    . ARG A 1 378 ? -15.21054 -10.72835 -4.87140 1.000 68.42019  ? 375 ARG A NE    1 
ATOM   3064 C  CZ    . ARG A 1 378 ? -15.66094 -9.49136  -5.04891 1.000 66.55243  ? 375 ARG A CZ    1 
ATOM   3065 N  NH1   . ARG A 1 378 ? -15.36378 -8.79210  -6.13591 1.000 58.31840  ? 375 ARG A NH1   1 
ATOM   3066 N  NH2   . ARG A 1 378 ? -16.42757 -8.94031  -4.11048 1.000 54.81695  ? 375 ARG A NH2   1 
ATOM   3067 N  N     . ALA A 1 379 ? -9.51547  -9.52635  -4.52471 1.000 40.72102  ? 376 ALA A N     1 
ATOM   3068 C  CA    . ALA A 1 379 ? -8.35265  -9.19008  -5.34247 1.000 39.62364  ? 376 ALA A CA    1 
ATOM   3069 C  C     . ALA A 1 379 ? -7.06159  -9.72778  -4.73938 1.000 47.32366  ? 376 ALA A C     1 
ATOM   3070 O  O     . ALA A 1 379 ? -6.17145  -10.17419 -5.47155 1.000 40.98123  ? 376 ALA A O     1 
ATOM   3071 C  CB    . ALA A 1 379 ? -8.26089  -7.67304  -5.52190 1.000 42.71815  ? 376 ALA A CB    1 
ATOM   3072 N  N     . ILE A 1 380 ? -6.93175  -9.67790  -3.40784 1.000 39.99539  ? 377 ILE A N     1 
ATOM   3073 C  CA    . ILE A 1 380 ? -5.74946  -10.23244 -2.75044 1.000 39.28909  ? 377 ILE A CA    1 
ATOM   3074 C  C     . ILE A 1 380 ? -5.63467  -11.72383 -3.03247 1.000 43.56142  ? 377 ILE A C     1 
ATOM   3075 O  O     . ILE A 1 380 ? -4.56420  -12.22787 -3.39397 1.000 46.23157  ? 377 ILE A O     1 
ATOM   3076 C  CB    . ILE A 1 380 ? -5.79820  -9.95490  -1.23529 1.000 32.10594  ? 377 ILE A CB    1 
ATOM   3077 C  CG1   . ILE A 1 380 ? -5.55314  -8.46925  -0.95529 1.000 38.40312  ? 377 ILE A CG1   1 
ATOM   3078 C  CG2   . ILE A 1 380 ? -4.78652  -10.82179 -0.48459 1.000 37.72133  ? 377 ILE A CG2   1 
ATOM   3079 C  CD1   . ILE A 1 380 ? -5.91860  -8.04263  0.44431  1.000 34.90038  ? 377 ILE A CD1   1 
ATOM   3080 N  N     . LEU A 1 381 ? -6.73744  -12.45463 -2.86426 1.000 40.37969  ? 378 LEU A N     1 
ATOM   3081 C  CA    . LEU A 1 381 ? -6.69013  -13.90904 -2.94153 1.000 46.37528  ? 378 LEU A CA    1 
ATOM   3082 C  C     . LEU A 1 381 ? -6.49722  -14.41604 -4.36132 1.000 52.64051  ? 378 LEU A C     1 
ATOM   3083 O  O     . LEU A 1 381 ? -6.14532  -15.58759 -4.54037 1.000 57.40786  ? 378 LEU A O     1 
ATOM   3084 C  CB    . LEU A 1 381 ? -7.96769  -14.49976 -2.34179 1.000 40.94099  ? 378 LEU A CB    1 
ATOM   3085 C  CG    . LEU A 1 381 ? -8.09840  -14.26977 -0.83442 1.000 41.07620  ? 378 LEU A CG    1 
ATOM   3086 C  CD1   . LEU A 1 381 ? -9.38382  -14.88176 -0.30607 1.000 46.08998  ? 378 LEU A CD1   1 
ATOM   3087 C  CD2   . LEU A 1 381 ? -6.88763  -14.82315 -0.09508 1.000 42.15732  ? 378 LEU A CD2   1 
ATOM   3088 N  N     . GLN A 1 382 ? -6.70562  -13.56879 -5.36435 1.000 45.42168  ? 379 GLN A N     1 
ATOM   3089 C  CA    . GLN A 1 382 ? -6.58151  -13.97400 -6.75413 1.000 66.11045  ? 379 GLN A CA    1 
ATOM   3090 C  C     . GLN A 1 382 ? -5.31249  -13.46190 -7.41929 1.000 62.67701  ? 379 GLN A C     1 
ATOM   3091 O  O     . GLN A 1 382 ? -5.04090  -13.83488 -8.56476 1.000 78.73282  ? 379 GLN A O     1 
ATOM   3092 C  CB    . GLN A 1 382 ? -7.81495  -13.51029 -7.54361 1.000 59.78538  ? 379 GLN A CB    1 
ATOM   3093 C  CG    . GLN A 1 382 ? -9.09259  -14.16529 -7.02517 1.000 71.17645  ? 379 GLN A CG    1 
ATOM   3094 C  CD    . GLN A 1 382 ? -10.33688 -13.74961 -7.78219 1.000 73.79316  ? 379 GLN A CD    1 
ATOM   3095 O  OE1   . GLN A 1 382 ? -10.36355 -12.70891 -8.43926 1.000 70.53741  ? 379 GLN A OE1   1 
ATOM   3096 N  NE2   . GLN A 1 382 ? -11.38624 -14.55788 -7.67726 1.000 79.82249  ? 379 GLN A NE2   1 
ATOM   3097 N  N     . ASN A 1 383 ? -4.52081  -12.64705 -6.73161 1.000 61.32569  ? 380 ASN A N     1 
ATOM   3098 C  CA    . ASN A 1 383 ? -3.22319  -12.23281 -7.24471 1.000 76.63994  ? 380 ASN A CA    1 
ATOM   3099 C  C     . ASN A 1 383 ? -2.19308  -13.34390 -7.03085 1.000 77.19565  ? 380 ASN A C     1 
ATOM   3100 O  O     . ASN A 1 383 ? -1.10503  -13.11031 -6.50275 1.000 73.11119  ? 380 ASN A O     1 
ATOM   3101 C  CB    . ASN A 1 383 ? -2.76794  -10.93797 -6.56869 1.000 71.21915  ? 380 ASN A CB    1 
ATOM   3102 C  CG    . ASN A 1 383 ? -1.68268  -10.22557 -7.34737 1.000 87.87434  ? 380 ASN A CG    1 
ATOM   3103 O  OD1   . ASN A 1 383 ? -1.71466  -10.18336 -8.57786 1.000 87.19412  ? 380 ASN A OD1   1 
ATOM   3104 N  ND2   . ASN A 1 383 ? -0.71935  -9.64872  -6.63244 1.000 83.36548  ? 380 ASN A ND2   1 
ATOM   3105 P  P     . DT  B 2 16  ? 1.64522   -31.88688 29.88079 1.000 76.27504  ? 10  DT  B P     1 
ATOM   3106 O  OP1   . DT  B 2 16  ? 0.63544   -30.79221 29.82945 1.000 53.67884  ? 10  DT  B OP1   1 
ATOM   3107 O  OP2   . DT  B 2 16  ? 2.39871   -32.33137 28.68677 1.000 54.09130  ? 10  DT  B OP2   1 
ATOM   3108 O  "O5'" . DT  B 2 16  ? 0.98992   -33.18808 30.53924 1.000 63.43233  ? 10  DT  B "O5'" 1 
ATOM   3109 C  "C5'" . DT  B 2 16  ? 1.81472   -34.13580 31.22115 1.000 59.77816  ? 10  DT  B "C5'" 1 
ATOM   3110 C  "C4'" . DT  B 2 16  ? 1.18843   -34.52726 32.54291 1.000 47.43545  ? 10  DT  B "C4'" 1 
ATOM   3111 O  "O4'" . DT  B 2 16  ? 2.13982   -34.28156 33.61298 1.000 55.22131  ? 10  DT  B "O4'" 1 
ATOM   3112 C  "C3'" . DT  B 2 16  ? -0.05171  -33.72313 32.90506 1.000 43.37233  ? 10  DT  B "C3'" 1 
ATOM   3113 O  "O3'" . DT  B 2 16  ? -0.91858  -34.47749 33.72961 1.000 37.49411  ? 10  DT  B "O3'" 1 
ATOM   3114 C  "C2'" . DT  B 2 16  ? 0.53786   -32.53300 33.65734 1.000 43.10712  ? 10  DT  B "C2'" 1 
ATOM   3115 C  "C1'" . DT  B 2 16  ? 1.76350   -33.13055 34.34054 1.000 42.80850  ? 10  DT  B "C1'" 1 
ATOM   3116 N  N1    . DT  B 2 16  ? 2.89960   -32.17202 34.37814 1.000 47.02117  ? 10  DT  B N1    1 
ATOM   3117 C  C2    . DT  B 2 16  ? 3.13349   -31.48740 35.53956 1.000 43.87785  ? 10  DT  B C2    1 
ATOM   3118 O  O2    . DT  B 2 16  ? 2.47933   -31.66371 36.55090 1.000 45.62544  ? 10  DT  B O2    1 
ATOM   3119 N  N3    . DT  B 2 16  ? 4.17766   -30.59895 35.48370 1.000 45.63493  ? 10  DT  B N3    1 
ATOM   3120 C  C4    . DT  B 2 16  ? 4.98793   -30.32552 34.39484 1.000 48.83115  ? 10  DT  B C4    1 
ATOM   3121 O  O4    . DT  B 2 16  ? 5.90325   -29.50806 34.44433 1.000 45.98270  ? 10  DT  B O4    1 
ATOM   3122 C  C5    . DT  B 2 16  ? 4.68018   -31.07002 33.19366 1.000 41.30822  ? 10  DT  B C5    1 
ATOM   3123 C  C7    . DT  B 2 16  ? 5.49077   -30.85724 31.95143 1.000 46.76748  ? 10  DT  B C7    1 
ATOM   3124 C  C6    . DT  B 2 16  ? 3.65422   -31.94081 33.23707 1.000 44.42122  ? 10  DT  B C6    1 
ATOM   3125 P  P     . DG  B 2 17  ? -2.05592  -35.41818 33.08871 1.000 32.98132  ? 11  DG  B P     1 
ATOM   3126 O  OP1   . DG  B 2 17  ? -2.18544  -36.53518 34.05972 1.000 30.97382  ? 11  DG  B OP1   1 
ATOM   3127 O  OP2   . DG  B 2 17  ? -1.76088  -35.75287 31.68315 1.000 33.95336  ? 11  DG  B OP2   1 
ATOM   3128 O  "O5'" . DG  B 2 17  ? -3.38462  -34.53432 33.13587 1.000 25.20765  ? 11  DG  B "O5'" 1 
ATOM   3129 C  "C5'" . DG  B 2 17  ? -3.89219  -34.03867 34.39200 1.000 26.72752  ? 11  DG  B "C5'" 1 
ATOM   3130 C  "C4'" . DG  B 2 17  ? -5.37515  -33.71114 34.28137 1.000 27.66832  ? 11  DG  B "C4'" 1 
ATOM   3131 O  "O4'" . DG  B 2 17  ? -5.56417  -32.52154 33.46869 1.000 24.46301  ? 11  DG  B "O4'" 1 
ATOM   3132 C  "C3'" . DG  B 2 17  ? -6.22454  -34.78972 33.62534 1.000 23.77141  ? 11  DG  B "C3'" 1 
ATOM   3133 O  "O3'" . DG  B 2 17  ? -7.51553  -34.78970 34.20214 1.000 26.23355  ? 11  DG  B "O3'" 1 
ATOM   3134 C  "C2'" . DG  B 2 17  ? -6.25719  -34.36385 32.14720 1.000 22.53715  ? 11  DG  B "C2'" 1 
ATOM   3135 C  "C1'" . DG  B 2 17  ? -6.25814  -32.84344 32.26639 1.000 26.34429  ? 11  DG  B "C1'" 1 
ATOM   3136 N  N9    . DG  B 2 17  ? -5.56285  -32.14246 31.19634 1.000 26.95797  ? 11  DG  B N9    1 
ATOM   3137 C  C8    . DG  B 2 17  ? -4.23239  -32.26015 30.84611 1.000 28.24871  ? 11  DG  B C8    1 
ATOM   3138 N  N7    . DG  B 2 17  ? -3.88112  -31.44914 29.87442 1.000 29.15209  ? 11  DG  B N7    1 
ATOM   3139 C  C5    . DG  B 2 17  ? -5.04616  -30.73724 29.59344 1.000 25.55757  ? 11  DG  B C5    1 
ATOM   3140 C  C6    . DG  B 2 17  ? -5.29115  -29.71519 28.63914 1.000 34.74027  ? 11  DG  B C6    1 
ATOM   3141 O  O6    . DG  B 2 17  ? -4.49453  -29.20559 27.84107 1.000 28.19390  ? 11  DG  B O6    1 
ATOM   3142 N  N1    . DG  B 2 17  ? -6.61439  -29.27341 28.68457 1.000 28.53489  ? 11  DG  B N1    1 
ATOM   3143 C  C2    . DG  B 2 17  ? -7.58046  -29.76727 29.52774 1.000 27.54758  ? 11  DG  B C2    1 
ATOM   3144 N  N2    . DG  B 2 17  ? -8.80182  -29.23076 29.41602 1.000 32.02971  ? 11  DG  B N2    1 
ATOM   3145 N  N3    . DG  B 2 17  ? -7.36582  -30.71120 30.42345 1.000 29.52133  ? 11  DG  B N3    1 
ATOM   3146 C  C4    . DG  B 2 17  ? -6.08302  -31.15469 30.39781 1.000 27.26591  ? 11  DG  B C4    1 
ATOM   3147 P  P     . DA  B 2 18  ? -8.01320  -36.04708 35.06779 1.000 26.01957  ? 12  DA  B P     1 
ATOM   3148 O  OP1   . DA  B 2 18  ? -7.78551  -37.28297 34.26702 1.000 23.35002  ? 12  DA  B OP1   1 
ATOM   3149 O  OP2   . DA  B 2 18  ? -9.35785  -35.69189 35.58104 1.000 26.68841  ? 12  DA  B OP2   1 
ATOM   3150 O  "O5'" . DA  B 2 18  ? -6.98799  -36.11779 36.28768 1.000 24.47014  ? 12  DA  B "O5'" 1 
ATOM   3151 C  "C5'" . DA  B 2 18  ? -7.21651  -35.30837 37.44377 1.000 21.89353  ? 12  DA  B "C5'" 1 
ATOM   3152 C  "C4'" . DA  B 2 18  ? -5.93675  -35.09569 38.23236 1.000 21.92634  ? 12  DA  B "C4'" 1 
ATOM   3153 O  "O4'" . DA  B 2 18  ? -5.04964  -34.22633 37.49619 1.000 21.04401  ? 12  DA  B "O4'" 1 
ATOM   3154 C  "C3'" . DA  B 2 18  ? -6.14716  -34.42384 39.57392 1.000 21.68991  ? 12  DA  B "C3'" 1 
ATOM   3155 O  "O3'" . DA  B 2 18  ? -6.36896  -35.42561 40.54530 1.000 22.71635  ? 12  DA  B "O3'" 1 
ATOM   3156 C  "C2'" . DA  B 2 18  ? -4.83055  -33.65758 39.80995 1.000 20.14713  ? 12  DA  B "C2'" 1 
ATOM   3157 C  "C1'" . DA  B 2 18  ? -4.32794  -33.37633 38.38094 1.000 18.78693  ? 12  DA  B "C1'" 1 
ATOM   3158 N  N9    . DA  B 2 18  ? -4.46943  -31.99587 37.89355 1.000 23.10357  ? 12  DA  B N9    1 
ATOM   3159 C  C8    . DA  B 2 18  ? -3.52503  -31.27950 37.19598 1.000 23.28992  ? 12  DA  B C8    1 
ATOM   3160 N  N7    . DA  B 2 18  ? -3.92354  -30.07622 36.84168 1.000 22.84775  ? 12  DA  B N7    1 
ATOM   3161 C  C5    . DA  B 2 18  ? -5.22061  -29.99856 37.31238 1.000 20.32962  ? 12  DA  B C5    1 
ATOM   3162 C  C6    . DA  B 2 18  ? -6.19052  -28.97788 37.25493 1.000 18.33170  ? 12  DA  B C6    1 
ATOM   3163 N  N6    . DA  B 2 18  ? -5.99138  -27.79150 36.64991 1.000 18.51699  ? 12  DA  B N6    1 
ATOM   3164 N  N1    . DA  B 2 18  ? -7.38686  -29.22338 37.82877 1.000 22.94267  ? 12  DA  B N1    1 
ATOM   3165 C  C2    . DA  B 2 18  ? -7.59259  -30.40647 38.41799 1.000 20.32558  ? 12  DA  B C2    1 
ATOM   3166 N  N3    . DA  B 2 18  ? -6.76422  -31.43795 38.52911 1.000 20.16234  ? 12  DA  B N3    1 
ATOM   3167 C  C4    . DA  B 2 18  ? -5.58179  -31.17305 37.95886 1.000 23.90251  ? 12  DA  B C4    1 
ATOM   3168 P  P     . DT  B 2 19  ? -6.94932  -35.06324 42.00386 1.000 26.32163  ? 13  DT  B P     1 
ATOM   3169 O  OP1   . DT  B 2 19  ? -8.18351  -34.25382 41.86272 1.000 28.83096  ? 13  DT  B OP1   1 
ATOM   3170 O  OP2   . DT  B 2 19  ? -5.83512  -34.52344 42.78819 1.000 29.10761  ? 13  DT  B OP2   1 
ATOM   3171 O  "O5'" . DT  B 2 19  ? -7.37780  -36.48677 42.56012 1.000 25.31573  ? 13  DT  B "O5'" 1 
ATOM   3172 C  "C5'" . DT  B 2 19  ? -8.30250  -37.29652 41.81430 1.000 23.91440  ? 13  DT  B "C5'" 1 
ATOM   3173 C  "C4'" . DT  B 2 19  ? -9.03098  -38.28913 42.71621 1.000 24.43318  ? 13  DT  B "C4'" 1 
ATOM   3174 O  "O4'" . DT  B 2 19  ? -8.07455  -39.21379 43.29523 1.000 26.08751  ? 13  DT  B "O4'" 1 
ATOM   3175 C  "C3'" . DT  B 2 19  ? -9.77530  -37.68591 43.91978 1.000 28.13775  ? 13  DT  B "C3'" 1 
ATOM   3176 O  "O3'" . DT  B 2 19  ? -10.84569 -38.54831 44.27902 1.000 39.75708  ? 13  DT  B "O3'" 1 
ATOM   3177 C  "C2'" . DT  B 2 19  ? -8.69811  -37.73341 44.99147 1.000 28.03666  ? 13  DT  B "C2'" 1 
ATOM   3178 C  "C1'" . DT  B 2 19  ? -8.12960  -39.11410 44.71606 1.000 29.20903  ? 13  DT  B "C1'" 1 
ATOM   3179 N  N1    . DT  B 2 19  ? -6.76551  -39.33630 45.25398 1.000 27.13721  ? 13  DT  B N1    1 
ATOM   3180 C  C2    . DT  B 2 19  ? -6.54937  -40.38537 46.12387 1.000 33.72732  ? 13  DT  B C2    1 
ATOM   3181 O  O2    . DT  B 2 19  ? -7.42780  -41.14591 46.48375 1.000 29.06601  ? 13  DT  B O2    1 
ATOM   3182 N  N3    . DT  B 2 19  ? -5.25476  -40.52371 46.54740 1.000 28.75319  ? 13  DT  B N3    1 
ATOM   3183 C  C4    . DT  B 2 19  ? -4.16970  -39.73672 46.19026 1.000 25.72248  ? 13  DT  B C4    1 
ATOM   3184 O  O4    . DT  B 2 19  ? -3.03827  -39.95095 46.62698 1.000 28.15952  ? 13  DT  B O4    1 
ATOM   3185 C  C5    . DT  B 2 19  ? -4.46218  -38.65548 45.26968 1.000 28.57408  ? 13  DT  B C5    1 
ATOM   3186 C  C7    . DT  B 2 19  ? -3.36853  -37.73640 44.80855 1.000 29.21538  ? 13  DT  B C7    1 
ATOM   3187 C  C6    . DT  B 2 19  ? -5.73247  -38.50715 44.85113 1.000 25.21681  ? 13  DT  B C6    1 
ATOM   3188 P  P     . DT  B 2 20  ? -12.37752 -38.18998 43.95224 1.000 59.13677  ? 14  DT  B P     1 
ATOM   3189 O  OP1   . DT  B 2 20  ? -12.44651 -37.19609 42.86061 1.000 53.09440  ? 14  DT  B OP1   1 
ATOM   3190 O  OP2   . DT  B 2 20  ? -13.03991 -37.93756 45.25412 1.000 57.49554  ? 14  DT  B OP2   1 
ATOM   3191 O  "O5'" . DT  B 2 20  ? -12.96249 -39.55591 43.38654 1.000 53.29196  ? 14  DT  B "O5'" 1 
HETATM 3192 ZN ZN    . ZN  C 3 .   ? -12.79563 -25.99697 48.46747 1.000 28.73774  ? 401 ZN  A ZN    1 
HETATM 3193 ZN ZN    . ZN  D 3 .   ? -0.57287  -10.40802 13.82464 1.000 25.28882  ? 402 ZN  A ZN    1 
HETATM 3194 P  P     . PO4 E 4 .   ? -2.96662  -8.22589  13.71663 1.000 26.51405  ? 403 PO4 A P     1 
HETATM 3195 O  O1    . PO4 E 4 .   ? -3.68908  -7.60553  12.52107 1.000 23.66949  ? 403 PO4 A O1    1 
HETATM 3196 O  O2    . PO4 E 4 .   ? -1.95937  -7.23759  14.24957 1.000 24.96587  ? 403 PO4 A O2    1 
HETATM 3197 O  O3    . PO4 E 4 .   ? -2.25140  -9.47805  13.29030 1.000 23.06722  ? 403 PO4 A O3    1 
HETATM 3198 O  O4    . PO4 E 4 .   ? -4.00609  -8.58549  14.75061 1.000 22.74168  ? 403 PO4 A O4    1 
HETATM 3199 O  O     . HOH F 5 .   ? -3.72073  -30.31285 43.71370 1.000 33.21171  ? 501 HOH A O     1 
HETATM 3200 O  O     . HOH F 5 .   ? -27.99926 -13.02512 15.82972 1.000 48.89249  ? 502 HOH A O     1 
HETATM 3201 O  O     . HOH F 5 .   ? -18.10837 -17.57816 27.00733 1.000 50.54294  ? 503 HOH A O     1 
HETATM 3202 O  O     . HOH F 5 .   ? -9.33039  -30.98087 53.58138 1.000 38.86814  ? 504 HOH A O     1 
HETATM 3203 O  O     . HOH F 5 .   ? -2.12113  -28.13835 55.11951 1.000 44.28095  ? 505 HOH A O     1 
HETATM 3204 O  O     . HOH F 5 .   ? 0.15216   -9.67146  28.47081 1.000 42.38254  ? 506 HOH A O     1 
HETATM 3205 O  O     . HOH F 5 .   ? -15.41917 -7.57134  44.13665 1.000 34.80175  ? 507 HOH A O     1 
HETATM 3206 O  O     . HOH F 5 .   ? 0.91637   -0.89077  9.29539  1.000 45.26367  ? 508 HOH A O     1 
HETATM 3207 O  O     . HOH F 5 .   ? 2.24300   -12.66886 15.32057 1.000 30.02839  ? 509 HOH A O     1 
HETATM 3208 O  O     . HOH F 5 .   ? -2.60099  -11.52465 61.96491 1.000 44.58061  ? 510 HOH A O     1 
HETATM 3209 O  O     . HOH F 5 .   ? -11.05573 -5.88308  42.90901 1.000 35.38606  ? 511 HOH A O     1 
HETATM 3210 O  O     . HOH F 5 .   ? -4.07869  -8.86626  6.99114  1.000 28.16038  ? 512 HOH A O     1 
HETATM 3211 O  O     . HOH F 5 .   ? -12.30525 -23.76245 40.33628 1.000 26.74145  ? 513 HOH A O     1 
HETATM 3212 O  O     . HOH F 5 .   ? -18.43861 -22.76210 20.62214 1.000 39.20177  ? 514 HOH A O     1 
HETATM 3213 O  O     . HOH F 5 .   ? -6.80894  -5.86798  66.27952 1.000 52.12040  ? 515 HOH A O     1 
HETATM 3214 O  O     . HOH F 5 .   ? -1.47160  -3.74361  51.26277 1.000 43.98125  ? 516 HOH A O     1 
HETATM 3215 O  O     . HOH F 5 .   ? -11.55713 -25.11574 47.30344 1.000 27.37942  ? 517 HOH A O     1 
HETATM 3216 O  O     . HOH F 5 .   ? -19.78030 -2.82298  51.17589 1.000 53.23301  ? 518 HOH A O     1 
HETATM 3217 O  O     . HOH F 5 .   ? -4.40296  0.21770   23.65625 1.000 35.86449  ? 519 HOH A O     1 
HETATM 3218 O  O     . HOH F 5 .   ? -9.11704  4.87157   19.39752 1.000 37.04524  ? 520 HOH A O     1 
HETATM 3219 O  O     . HOH F 5 .   ? -25.42770 -0.41744  5.57514  1.000 50.37327  ? 521 HOH A O     1 
HETATM 3220 O  O     . HOH F 5 .   ? -12.04400 -16.31738 26.19814 1.000 31.01309  ? 522 HOH A O     1 
HETATM 3221 O  O     . HOH F 5 .   ? -13.92559 -33.32789 40.83977 1.000 39.12403  ? 523 HOH A O     1 
HETATM 3222 O  O     . HOH F 5 .   ? -18.93641 -5.31104  58.25613 1.000 44.71558  ? 524 HOH A O     1 
HETATM 3223 O  O     . HOH F 5 .   ? 3.79305   -5.94969  42.19157 1.000 35.85602  ? 525 HOH A O     1 
HETATM 3224 O  O     . HOH F 5 .   ? 5.21349   -4.65685  38.96317 1.000 37.10280  ? 526 HOH A O     1 
HETATM 3225 O  O     . HOH F 5 .   ? -2.36316  -17.65392 25.25514 1.000 33.24851  ? 527 HOH A O     1 
HETATM 3226 O  O     . HOH F 5 .   ? 11.86172  -12.05477 54.62911 1.000 45.60124  ? 528 HOH A O     1 
HETATM 3227 O  O     . HOH F 5 .   ? -24.38081 -21.13099 46.77386 1.000 56.21773  ? 529 HOH A O     1 
HETATM 3228 O  O     . HOH F 5 .   ? -13.42331 1.46772   11.57064 1.000 24.66583  ? 530 HOH A O     1 
HETATM 3229 O  O     . HOH F 5 .   ? -14.40825 0.83109   55.69229 1.000 34.99819  ? 531 HOH A O     1 
HETATM 3230 O  O     . HOH F 5 .   ? -24.92626 -20.34701 35.50461 1.000 62.63900  ? 532 HOH A O     1 
HETATM 3231 O  O     . HOH F 5 .   ? -9.71201  -3.29896  16.46324 1.000 19.70493  ? 533 HOH A O     1 
HETATM 3232 O  O     . HOH F 5 .   ? -10.99272 -3.99378  26.30358 1.000 46.23569  ? 534 HOH A O     1 
HETATM 3233 O  O     . HOH F 5 .   ? -17.38851 -22.61753 13.97439 1.000 33.05035  ? 535 HOH A O     1 
HETATM 3234 O  O     . HOH F 5 .   ? -1.77743  -23.91319 19.07397 1.000 34.13710  ? 536 HOH A O     1 
HETATM 3235 O  O     . HOH F 5 .   ? 8.41366   -15.86340 32.78888 1.000 39.60171  ? 537 HOH A O     1 
HETATM 3236 O  O     . HOH F 5 .   ? -1.43898  -23.72080 23.96885 1.000 35.69353  ? 538 HOH A O     1 
HETATM 3237 O  O     . HOH F 5 .   ? -26.84076 -12.64040 12.04405 1.000 49.86584  ? 539 HOH A O     1 
HETATM 3238 O  O     . HOH F 5 .   ? -22.72242 -22.15436 15.66083 1.000 53.11667  ? 540 HOH A O     1 
HETATM 3239 O  O     . HOH F 5 .   ? -10.34952 -0.64161  22.26515 1.000 33.02974  ? 541 HOH A O     1 
HETATM 3240 O  O     . HOH F 5 .   ? 4.25780   -5.21516  46.72359 1.000 37.55094  ? 542 HOH A O     1 
HETATM 3241 O  O     . HOH F 5 .   ? -18.81472 1.95372   60.92197 1.000 54.64946  ? 543 HOH A O     1 
HETATM 3242 O  O     . HOH F 5 .   ? 4.38156   -8.49440  9.05701  1.000 53.18089  ? 544 HOH A O     1 
HETATM 3243 O  O     . HOH F 5 .   ? -8.89205  -0.10374  18.86851 1.000 23.47524  ? 545 HOH A O     1 
HETATM 3244 O  O     . HOH F 5 .   ? -12.12791 -6.68261  70.56021 1.000 42.57329  ? 546 HOH A O     1 
HETATM 3245 O  O     . HOH F 5 .   ? -16.93559 -15.12036 57.63118 1.000 35.61684  ? 547 HOH A O     1 
HETATM 3246 O  O     . HOH F 5 .   ? -7.69406  -29.56379 20.98162 1.000 33.19908  ? 548 HOH A O     1 
HETATM 3247 O  O     . HOH F 5 .   ? -18.51445 -6.74611  61.05716 1.000 36.88533  ? 549 HOH A O     1 
HETATM 3248 O  O     . HOH F 5 .   ? -17.80328 -6.49981  -3.30196 1.000 57.42585  ? 550 HOH A O     1 
HETATM 3249 O  O     . HOH F 5 .   ? -16.01237 -5.82856  62.26535 1.000 37.97808  ? 551 HOH A O     1 
HETATM 3250 O  O     . HOH F 5 .   ? -13.61167 -15.12493 0.48387  1.000 50.52802  ? 552 HOH A O     1 
HETATM 3251 O  O     . HOH F 5 .   ? -4.93350  -29.81688 6.41153  1.000 71.49724  ? 553 HOH A O     1 
HETATM 3252 O  O     . HOH F 5 .   ? -18.94120 -23.22576 31.00867 1.000 51.73872  ? 554 HOH A O     1 
HETATM 3253 O  O     . HOH F 5 .   ? 0.40063   -6.17931  13.56447 1.000 29.35640  ? 555 HOH A O     1 
HETATM 3254 O  O     . HOH F 5 .   ? -1.23405  -25.33792 45.75568 1.000 20.58153  ? 556 HOH A O     1 
HETATM 3255 O  O     . HOH F 5 .   ? -29.76685 -7.83989  17.06893 1.000 51.32231  ? 557 HOH A O     1 
HETATM 3256 O  O     . HOH F 5 .   ? -2.88414  -6.22155  41.74608 1.000 39.19506  ? 558 HOH A O     1 
HETATM 3257 O  O     . HOH F 5 .   ? -4.16212  -11.24949 15.10377 1.000 19.99402  ? 559 HOH A O     1 
HETATM 3258 O  O     . HOH F 5 .   ? -20.77073 6.32860   -0.87383 1.000 41.11700  ? 560 HOH A O     1 
HETATM 3259 O  O     . HOH F 5 .   ? -11.91577 -11.64092 35.28485 1.000 44.67434  ? 561 HOH A O     1 
HETATM 3260 O  O     . HOH F 5 .   ? -3.34137  -8.75745  17.35799 1.000 21.00379  ? 562 HOH A O     1 
HETATM 3261 O  O     . HOH F 5 .   ? -1.55850  -35.16081 41.19128 1.000 27.07809  ? 563 HOH A O     1 
HETATM 3262 O  O     . HOH F 5 .   ? -24.72052 -16.33668 43.47961 1.000 37.95876  ? 564 HOH A O     1 
HETATM 3263 O  O     . HOH F 5 .   ? 0.94527   -22.54542 14.74809 1.000 42.94469  ? 565 HOH A O     1 
HETATM 3264 O  O     . HOH F 5 .   ? -25.59561 3.49729   5.81105  1.000 47.54448  ? 566 HOH A O     1 
HETATM 3265 O  O     . HOH F 5 .   ? -0.49971  5.46555   16.26391 1.000 26.93854  ? 567 HOH A O     1 
HETATM 3266 O  O     . HOH F 5 .   ? -2.09715  -31.22392 41.59865 1.000 23.99929  ? 568 HOH A O     1 
HETATM 3267 O  O     . HOH F 5 .   ? 10.46353  -8.80130  40.68771 1.000 34.80510  ? 569 HOH A O     1 
HETATM 3268 O  O     . HOH F 5 .   ? -21.66529 -19.63939 53.76322 1.000 45.64640  ? 570 HOH A O     1 
HETATM 3269 O  O     . HOH F 5 .   ? -4.27787  -0.10678  13.18036 1.000 29.96972  ? 571 HOH A O     1 
HETATM 3270 O  O     . HOH F 5 .   ? -0.31946  -19.30660 26.18919 1.000 37.43484  ? 572 HOH A O     1 
HETATM 3271 O  O     . HOH F 5 .   ? -21.34658 -8.69801  49.44301 1.000 24.11256  ? 573 HOH A O     1 
HETATM 3272 O  O     . HOH F 5 .   ? -24.90785 -10.19063 5.51454  1.000 50.05953  ? 574 HOH A O     1 
HETATM 3273 O  O     . HOH F 5 .   ? -6.24780  3.52427   53.53365 1.000 67.65588  ? 575 HOH A O     1 
HETATM 3274 O  O     . HOH F 5 .   ? -4.65997  -3.31889  62.41537 1.000 46.36706  ? 576 HOH A O     1 
HETATM 3275 O  O     . HOH F 5 .   ? -4.64197  -33.43988 49.80163 1.000 29.90646  ? 577 HOH A O     1 
HETATM 3276 O  O     . HOH F 5 .   ? -4.25031  -9.97467  36.92087 1.000 33.94302  ? 578 HOH A O     1 
HETATM 3277 O  O     . HOH F 5 .   ? -12.30629 3.26284   59.00848 1.000 48.47865  ? 579 HOH A O     1 
HETATM 3278 O  O     . HOH F 5 .   ? 2.64084   -11.78486 32.15284 1.000 28.17952  ? 580 HOH A O     1 
HETATM 3279 O  O     . HOH F 5 .   ? 4.13968   -9.57724  18.30570 1.000 32.94840  ? 581 HOH A O     1 
HETATM 3280 O  O     . HOH F 5 .   ? -5.47149  -12.48600 25.14861 1.000 40.12728  ? 582 HOH A O     1 
HETATM 3281 O  O     . HOH F 5 .   ? -4.25657  -28.96624 18.57299 1.000 47.76806  ? 583 HOH A O     1 
HETATM 3282 O  O     . HOH F 5 .   ? -22.79255 -13.54007 30.73988 1.000 45.86615  ? 584 HOH A O     1 
HETATM 3283 O  O     . HOH F 5 .   ? -22.24365 0.82545   20.96580 1.000 45.15045  ? 585 HOH A O     1 
HETATM 3284 O  O     . HOH F 5 .   ? -23.10694 -6.41975  4.80881  1.000 44.66414  ? 586 HOH A O     1 
HETATM 3285 O  O     . HOH F 5 .   ? 1.57378   -7.77372  1.26234  1.000 39.16709  ? 587 HOH A O     1 
HETATM 3286 O  O     . HOH F 5 .   ? -8.23679  -5.81953  50.12457 1.000 33.93352  ? 588 HOH A O     1 
HETATM 3287 O  O     . HOH F 5 .   ? -12.71493 -2.39107  61.66797 1.000 37.41339  ? 589 HOH A O     1 
HETATM 3288 O  O     . HOH F 5 .   ? -9.59085  -25.66323 45.28757 1.000 28.50702  ? 590 HOH A O     1 
HETATM 3289 O  O     . HOH F 5 .   ? -1.48889  -17.22957 36.75068 1.000 19.85543  ? 591 HOH A O     1 
HETATM 3290 O  O     . HOH F 5 .   ? -9.21166  -24.91087 7.72006  1.000 45.82085  ? 592 HOH A O     1 
HETATM 3291 O  O     . HOH F 5 .   ? -7.89165  -6.08487  45.52097 1.000 42.90795  ? 593 HOH A O     1 
HETATM 3292 O  O     . HOH F 5 .   ? -12.52392 -0.04395  24.46559 1.000 49.45239  ? 594 HOH A O     1 
HETATM 3293 O  O     . HOH F 5 .   ? 2.62951   -8.60663  27.46320 1.000 23.79117  ? 595 HOH A O     1 
HETATM 3294 O  O     . HOH F 5 .   ? 4.99696   -27.62569 42.02919 1.000 29.33606  ? 596 HOH A O     1 
HETATM 3295 O  O     . HOH F 5 .   ? -5.38783  -24.26969 35.62942 1.000 17.94142  ? 597 HOH A O     1 
HETATM 3296 O  O     . HOH F 5 .   ? -4.76514  -17.52923 24.89143 1.000 26.36275  ? 598 HOH A O     1 
HETATM 3297 O  O     . HOH F 5 .   ? 9.86586   -8.49463  44.48184 1.000 32.76732  ? 599 HOH A O     1 
HETATM 3298 O  O     . HOH F 5 .   ? -20.90619 -25.10251 32.60101 1.000 48.10506  ? 600 HOH A O     1 
HETATM 3299 O  O     . HOH F 5 .   ? -0.25951  -7.24415  20.57091 1.000 25.10456  ? 601 HOH A O     1 
HETATM 3300 O  O     . HOH F 5 .   ? -1.56599  -6.58911  16.93478 1.000 25.36203  ? 602 HOH A O     1 
HETATM 3301 O  O     . HOH F 5 .   ? -9.71521  -20.83220 46.01703 1.000 27.60492  ? 603 HOH A O     1 
HETATM 3302 O  O     . HOH F 5 .   ? 1.50442   -15.16798 -2.63661 1.000 54.06558  ? 604 HOH A O     1 
HETATM 3303 O  O     . HOH F 5 .   ? -6.96359  -0.79959  55.71721 1.000 43.90260  ? 605 HOH A O     1 
HETATM 3304 O  O     . HOH F 5 .   ? -18.67436 -0.12538  -1.67128 1.000 37.64314  ? 606 HOH A O     1 
HETATM 3305 O  O     . HOH F 5 .   ? -21.92027 -26.69995 40.46396 1.000 41.87263  ? 607 HOH A O     1 
HETATM 3306 O  O     . HOH F 5 .   ? 8.88527   -17.21174 29.95981 1.000 43.00766  ? 608 HOH A O     1 
HETATM 3307 O  O     . HOH F 5 .   ? 7.13945   -11.36091 22.94723 1.000 28.95602  ? 609 HOH A O     1 
HETATM 3308 O  O     . HOH F 5 .   ? -17.69163 -9.17532  46.46060 1.000 32.82578  ? 610 HOH A O     1 
HETATM 3309 O  O     . HOH F 5 .   ? 2.49563   -2.06460  25.36742 1.000 31.37453  ? 611 HOH A O     1 
HETATM 3310 O  O     . HOH F 5 .   ? -3.74066  -30.92284 23.07736 1.000 43.50997  ? 612 HOH A O     1 
HETATM 3311 O  O     . HOH F 5 .   ? 8.57758   -11.69741 30.37388 1.000 28.09832  ? 613 HOH A O     1 
HETATM 3312 O  O     . HOH F 5 .   ? -25.88358 0.73377   7.84850  1.000 48.04779  ? 614 HOH A O     1 
HETATM 3313 O  O     . HOH F 5 .   ? -23.79467 1.03523   3.29293  1.000 43.21555  ? 615 HOH A O     1 
HETATM 3314 O  O     . HOH F 5 .   ? -22.87029 -1.53517  16.96423 1.000 40.03042  ? 616 HOH A O     1 
HETATM 3315 O  O     . HOH F 5 .   ? -16.34449 -8.25601  70.90599 1.000 41.56525  ? 617 HOH A O     1 
HETATM 3316 O  O     . HOH F 5 .   ? -3.65967  -5.80810  17.74504 1.000 34.73207  ? 618 HOH A O     1 
HETATM 3317 O  O     . HOH F 5 .   ? -23.48806 1.35293   15.80246 1.000 50.19632  ? 619 HOH A O     1 
HETATM 3318 O  O     . HOH F 5 .   ? 10.25153  -5.11164  25.05069 1.000 35.01866  ? 620 HOH A O     1 
HETATM 3319 O  O     . HOH F 5 .   ? -16.36871 -5.58625  6.71129  1.000 30.64857  ? 621 HOH A O     1 
HETATM 3320 O  O     . HOH F 5 .   ? 9.68615   -11.30241 50.20155 1.000 36.52168  ? 622 HOH A O     1 
HETATM 3321 O  O     . HOH F 5 .   ? -7.10146  -0.95656  16.26312 1.000 21.65101  ? 623 HOH A O     1 
HETATM 3322 O  O     . HOH F 5 .   ? -1.42740  -14.62964 61.21488 1.000 41.34112  ? 624 HOH A O     1 
HETATM 3323 O  O     . HOH F 5 .   ? -18.41420 -6.14146  29.78941 1.000 44.48055  ? 625 HOH A O     1 
HETATM 3324 O  O     . HOH F 5 .   ? 6.94395   -22.88675 34.81290 1.000 31.81077  ? 626 HOH A O     1 
HETATM 3325 O  O     . HOH F 5 .   ? -20.22576 -14.67571 35.39036 1.000 42.04530  ? 627 HOH A O     1 
HETATM 3326 O  O     . HOH F 5 .   ? 6.46309   -22.31024 54.51002 1.000 36.19657  ? 628 HOH A O     1 
HETATM 3327 O  O     . HOH F 5 .   ? 4.36908   -13.60399 21.51687 1.000 23.95481  ? 629 HOH A O     1 
HETATM 3328 O  O     . HOH F 5 .   ? 3.87190   -17.70958 2.69686  1.000 52.05581  ? 630 HOH A O     1 
HETATM 3329 O  O     . HOH F 5 .   ? -9.70304  -20.61314 60.76920 1.000 33.76104  ? 631 HOH A O     1 
HETATM 3330 O  O     . HOH F 5 .   ? -14.57131 3.11102   15.30798 1.000 37.83242  ? 632 HOH A O     1 
HETATM 3331 O  O     . HOH F 5 .   ? 2.42841   -29.80004 51.01854 1.000 35.63698  ? 633 HOH A O     1 
HETATM 3332 O  O     . HOH F 5 .   ? -0.34382  -2.90500  18.72243 1.000 27.05016  ? 634 HOH A O     1 
HETATM 3333 O  O     . HOH F 5 .   ? 11.26057  -21.72986 35.48804 1.000 42.75309  ? 635 HOH A O     1 
HETATM 3334 O  O     . HOH F 5 .   ? -10.20359 -25.01926 60.85338 1.000 55.75705  ? 636 HOH A O     1 
HETATM 3335 O  O     . HOH F 5 .   ? -9.04285  -2.21577  5.78935  1.000 27.13767  ? 637 HOH A O     1 
HETATM 3336 O  O     . HOH F 5 .   ? -21.05818 -25.63043 50.08825 1.000 40.17378  ? 638 HOH A O     1 
HETATM 3337 O  O     . HOH F 5 .   ? -4.46599  -1.39134  7.44670  1.000 36.08147  ? 639 HOH A O     1 
HETATM 3338 O  O     . HOH F 5 .   ? -6.75584  -33.49659 22.15608 1.000 51.20022  ? 640 HOH A O     1 
HETATM 3339 O  O     . HOH F 5 .   ? 10.93117  -15.58542 43.28632 1.000 31.30009  ? 641 HOH A O     1 
HETATM 3340 O  O     . HOH F 5 .   ? -15.92966 -12.26271 38.80660 1.000 39.77171  ? 642 HOH A O     1 
HETATM 3341 O  O     . HOH F 5 .   ? -17.06947 -3.42270  50.93593 1.000 35.30979  ? 643 HOH A O     1 
HETATM 3342 O  O     . HOH F 5 .   ? -17.18349 -15.39007 27.04811 1.000 42.54243  ? 644 HOH A O     1 
HETATM 3343 O  O     . HOH F 5 .   ? -1.36147  -12.16444 6.45409  1.000 31.56968  ? 645 HOH A O     1 
HETATM 3344 O  O     . HOH F 5 .   ? -11.75331 -33.09251 26.12625 1.000 52.94997  ? 646 HOH A O     1 
HETATM 3345 O  O     . HOH F 5 .   ? 0.73912   -9.58340  31.07264 1.000 34.57221  ? 647 HOH A O     1 
HETATM 3346 O  O     . HOH F 5 .   ? -9.94891  -22.69366 27.43438 1.000 36.52806  ? 648 HOH A O     1 
HETATM 3347 O  O     . HOH F 5 .   ? -14.83829 -39.36399 20.31959 1.000 63.06009  ? 649 HOH A O     1 
HETATM 3348 O  O     . HOH F 5 .   ? -19.38931 3.94321   10.14913 1.000 51.79300  ? 650 HOH A O     1 
HETATM 3349 O  O     . HOH F 5 .   ? -8.00016  -12.47956 34.79580 1.000 28.85254  ? 651 HOH A O     1 
HETATM 3350 O  O     . HOH F 5 .   ? -18.58521 -10.33937 39.86057 1.000 39.09309  ? 652 HOH A O     1 
HETATM 3351 O  O     . HOH F 5 .   ? -10.24363 1.45725   60.44754 1.000 37.38770  ? 653 HOH A O     1 
HETATM 3352 O  O     . HOH F 5 .   ? -16.98893 -35.74309 13.25452 1.000 48.97124  ? 654 HOH A O     1 
HETATM 3353 O  O     . HOH F 5 .   ? -2.39055  -2.92478  21.49662 1.000 27.94861  ? 655 HOH A O     1 
HETATM 3354 O  O     . HOH F 5 .   ? 1.54154   -2.00197  61.89715 1.000 63.61843  ? 656 HOH A O     1 
HETATM 3355 O  O     . HOH F 5 .   ? -11.67194 -6.52008  47.19009 1.000 33.13817  ? 657 HOH A O     1 
HETATM 3356 O  O     . HOH F 5 .   ? -10.33563 -22.44421 1.68933  1.000 48.29158  ? 658 HOH A O     1 
HETATM 3357 O  O     . HOH F 5 .   ? -13.44025 6.77919   8.05127  1.000 30.20105  ? 659 HOH A O     1 
HETATM 3358 O  O     . HOH F 5 .   ? -6.54896  -29.50611 55.72556 1.000 36.49209  ? 660 HOH A O     1 
HETATM 3359 O  O     . HOH F 5 .   ? -6.92297  -28.43799 8.78196  1.000 51.18904  ? 661 HOH A O     1 
HETATM 3360 O  O     . HOH F 5 .   ? -11.78549 -1.88618  65.44726 1.000 37.60722  ? 662 HOH A O     1 
HETATM 3361 O  O     . HOH F 5 .   ? 7.19614   -12.48842 33.84444 1.000 31.48139  ? 663 HOH A O     1 
HETATM 3362 O  O     . HOH F 5 .   ? -6.45526  -11.48090 13.46311 1.000 30.50011  ? 664 HOH A O     1 
HETATM 3363 O  O     . HOH F 5 .   ? 11.40483  -19.32396 55.58199 1.000 40.21086  ? 665 HOH A O     1 
HETATM 3364 O  O     . HOH F 5 .   ? -25.42882 -2.01034  18.16054 1.000 37.35758  ? 666 HOH A O     1 
HETATM 3365 O  O     . HOH F 5 .   ? -15.97657 -24.50685 41.40667 1.000 33.90014  ? 667 HOH A O     1 
HETATM 3366 O  O     . HOH F 5 .   ? -13.31019 3.66875   12.90040 1.000 30.75811  ? 668 HOH A O     1 
HETATM 3367 O  O     . HOH F 5 .   ? -17.05318 -8.30607  39.86892 1.000 44.13142  ? 669 HOH A O     1 
HETATM 3368 O  O     . HOH F 5 .   ? -23.31026 -13.66069 55.31613 1.000 53.80585  ? 670 HOH A O     1 
HETATM 3369 O  O     . HOH F 5 .   ? 9.79941   -10.64164 33.97605 1.000 31.76224  ? 671 HOH A O     1 
HETATM 3370 O  O     . HOH F 5 .   ? -19.04803 -26.84948 29.51853 1.000 55.33763  ? 672 HOH A O     1 
HETATM 3371 O  O     . HOH F 5 .   ? -10.76545 4.42190   13.78529 1.000 28.39838  ? 673 HOH A O     1 
HETATM 3372 O  O     . HOH F 5 .   ? 10.97539  -23.14038 56.28753 1.000 35.83486  ? 674 HOH A O     1 
HETATM 3373 O  O     . HOH F 5 .   ? -19.20981 5.52018   7.11994  1.000 45.49411  ? 675 HOH A O     1 
HETATM 3374 O  O     . HOH F 5 .   ? -21.20998 -22.72641 18.01932 1.000 47.94888  ? 676 HOH A O     1 
HETATM 3375 O  O     . HOH F 5 .   ? -18.19792 1.60979   56.57009 1.000 41.69968  ? 677 HOH A O     1 
HETATM 3376 O  O     . HOH F 5 .   ? -15.49255 -11.48482 1.73802  1.000 33.86711  ? 678 HOH A O     1 
HETATM 3377 O  O     . HOH F 5 .   ? 8.54853   -5.05874  44.17856 1.000 39.62005  ? 679 HOH A O     1 
HETATM 3378 O  O     . HOH F 5 .   ? -13.92416 -33.11385 22.09224 1.000 45.77417  ? 680 HOH A O     1 
HETATM 3379 O  O     . HOH F 5 .   ? 5.44525   -8.87741  6.98513  1.000 49.13480  ? 681 HOH A O     1 
HETATM 3380 O  O     . HOH F 5 .   ? -20.06662 -10.00223 31.16380 1.000 46.29833  ? 682 HOH A O     1 
HETATM 3381 O  O     . HOH F 5 .   ? -20.29199 -9.23261  46.91514 1.000 36.36214  ? 683 HOH A O     1 
HETATM 3382 O  O     . HOH F 5 .   ? -15.57082 -29.93450 44.37102 1.000 41.49272  ? 684 HOH A O     1 
HETATM 3383 O  O     . HOH F 5 .   ? -1.46871  -16.37260 59.11777 1.000 34.81566  ? 685 HOH A O     1 
HETATM 3384 O  O     . HOH F 5 .   ? 1.14222   -8.04203  35.81635 1.000 25.49332  ? 686 HOH A O     1 
HETATM 3385 O  O     . HOH F 5 .   ? -19.23408 -3.35059  65.75615 1.000 56.40819  ? 687 HOH A O     1 
HETATM 3386 O  O     . HOH F 5 .   ? -3.06436  -8.70291  34.48067 1.000 30.97980  ? 688 HOH A O     1 
HETATM 3387 O  O     . HOH F 5 .   ? -22.50512 -15.58690 34.97023 1.000 50.96846  ? 689 HOH A O     1 
HETATM 3388 O  O     . HOH F 5 .   ? -4.08283  -9.24529  29.73351 1.000 45.07950  ? 690 HOH A O     1 
HETATM 3389 O  O     . HOH F 5 .   ? 9.16844   -5.42152  38.65722 1.000 38.90148  ? 691 HOH A O     1 
HETATM 3390 O  O     . HOH F 5 .   ? -14.24982 -11.62288 -0.59204 1.000 44.80512  ? 692 HOH A O     1 
HETATM 3391 O  O     . HOH F 5 .   ? 9.39366   -19.12333 56.57301 1.000 41.91835  ? 693 HOH A O     1 
HETATM 3392 O  O     . HOH F 5 .   ? 0.03282   -6.12306  28.12359 1.000 33.21672  ? 694 HOH A O     1 
HETATM 3393 O  O     . HOH F 5 .   ? -0.02239  -19.80169 18.58873 1.000 42.49384  ? 695 HOH A O     1 
HETATM 3394 O  O     . HOH F 5 .   ? -2.83983  -5.81215  26.34060 1.000 38.04530  ? 696 HOH A O     1 
HETATM 3395 O  O     . HOH F 5 .   ? -14.65988 -17.45188 6.69644  1.000 44.25077  ? 697 HOH A O     1 
HETATM 3396 O  O     . HOH F 5 .   ? 2.42569   -9.99621  -0.18328 1.000 42.69701  ? 698 HOH A O     1 
HETATM 3397 O  O     . HOH F 5 .   ? -14.65884 -14.76323 26.71723 1.000 32.45040  ? 699 HOH A O     1 
HETATM 3398 O  O     . HOH F 5 .   ? -14.90348 -5.58447  26.95703 1.000 36.27570  ? 700 HOH A O     1 
HETATM 3399 O  O     . HOH F 5 .   ? -17.22400 2.26169   -0.93329 1.000 32.93314  ? 701 HOH A O     1 
HETATM 3400 O  O     . HOH F 5 .   ? -23.46505 -2.99603  28.82416 1.000 53.32458  ? 702 HOH A O     1 
HETATM 3401 O  O     . HOH F 5 .   ? 2.43790   -27.09248 50.56605 1.000 24.78244  ? 703 HOH A O     1 
HETATM 3402 O  O     . HOH F 5 .   ? 0.83827   -26.07747 14.92794 1.000 52.68937  ? 704 HOH A O     1 
HETATM 3403 O  O     . HOH F 5 .   ? -5.64616  -15.04960 25.81608 1.000 30.68828  ? 705 HOH A O     1 
HETATM 3404 O  O     . HOH F 5 .   ? -7.39428  1.92525   56.42928 1.000 52.56401  ? 706 HOH A O     1 
HETATM 3405 O  O     . HOH F 5 .   ? -21.83525 -5.63773  48.54462 1.000 56.41892  ? 707 HOH A O     1 
HETATM 3406 O  O     . HOH F 5 .   ? -6.09668  -3.14950  47.69196 1.000 49.44258  ? 708 HOH A O     1 
HETATM 3407 O  O     . HOH F 5 .   ? -10.15316 -13.33185 27.22586 1.000 37.54856  ? 709 HOH A O     1 
HETATM 3408 O  O     . HOH F 5 .   ? 2.60114   -11.78430 18.14000 1.000 24.23303  ? 710 HOH A O     1 
HETATM 3409 O  O     . HOH F 5 .   ? 1.94664   -3.46277  55.24096 1.000 53.45498  ? 711 HOH A O     1 
HETATM 3410 O  O     . HOH F 5 .   ? 3.13724   -19.80889 56.27497 1.000 48.98010  ? 712 HOH A O     1 
HETATM 3411 O  O     . HOH F 5 .   ? -4.19652  -22.62018 57.92066 1.000 32.15310  ? 713 HOH A O     1 
HETATM 3412 O  O     . HOH F 5 .   ? 7.24435   -14.21177 27.40820 1.000 40.83358  ? 714 HOH A O     1 
HETATM 3413 O  O     . HOH F 5 .   ? -13.40750 -36.88852 37.18790 1.000 49.87669  ? 715 HOH A O     1 
HETATM 3414 O  O     . HOH F 5 .   ? -15.52640 -27.64765 29.09392 1.000 50.53731  ? 716 HOH A O     1 
HETATM 3415 O  O     . HOH F 5 .   ? -14.34098 8.42648   10.00272 1.000 45.87914  ? 717 HOH A O     1 
HETATM 3416 O  O     . HOH F 5 .   ? -18.15752 -13.05055 58.74054 1.000 37.35722  ? 718 HOH A O     1 
HETATM 3417 O  O     . HOH F 5 .   ? -8.11449  1.95393   23.43647 1.000 45.14063  ? 719 HOH A O     1 
HETATM 3418 O  O     . HOH F 5 .   ? -16.45381 -11.55899 36.64127 1.000 50.53689  ? 720 HOH A O     1 
HETATM 3419 O  O     . HOH F 5 .   ? -7.70692  -11.18867 26.16304 1.000 27.29894  ? 721 HOH A O     1 
HETATM 3420 O  O     . HOH F 5 .   ? 11.12039  -18.94355 40.49809 1.000 46.99035  ? 722 HOH A O     1 
HETATM 3421 O  O     . HOH F 5 .   ? -0.52501  -26.69140 31.20383 1.000 25.30664  ? 723 HOH A O     1 
HETATM 3422 O  O     . HOH F 5 .   ? -3.78517  -18.58130 59.90953 1.000 50.80830  ? 724 HOH A O     1 
HETATM 3423 O  O     . HOH F 5 .   ? -16.68755 -25.82237 51.21019 1.000 44.57940  ? 725 HOH A O     1 
HETATM 3424 O  O     . HOH F 5 .   ? -8.65914  -0.20084  0.44268  1.000 46.67371  ? 726 HOH A O     1 
HETATM 3425 O  O     . HOH F 5 .   ? 3.51066   -31.55542 50.17114 1.000 35.92078  ? 727 HOH A O     1 
HETATM 3426 O  O     . HOH F 5 .   ? -22.71104 5.52927   12.58286 1.000 48.10394  ? 728 HOH A O     1 
HETATM 3427 O  O     . HOH F 5 .   ? 2.52267   -3.56335  2.33376  1.000 54.91839  ? 729 HOH A O     1 
HETATM 3428 O  O     . HOH F 5 .   ? -7.96420  -13.34978 27.46076 1.000 47.11315  ? 730 HOH A O     1 
HETATM 3429 O  O     . HOH F 5 .   ? 7.30603   -4.11745  37.11441 1.000 45.24415  ? 731 HOH A O     1 
HETATM 3430 O  O     . HOH F 5 .   ? 5.73499   -16.99606 28.38337 1.000 33.82353  ? 732 HOH A O     1 
HETATM 3431 O  O     . HOH F 5 .   ? -19.94390 5.35719   12.12262 1.000 47.47356  ? 733 HOH A O     1 
HETATM 3432 O  O     . HOH F 5 .   ? -15.29825 -29.94698 46.88225 1.000 43.18464  ? 734 HOH A O     1 
HETATM 3433 O  O     . HOH F 5 .   ? 2.50574   -19.42864 18.00001 1.000 48.03510  ? 735 HOH A O     1 
HETATM 3434 O  O     . HOH F 5 .   ? -2.49727  -34.41121 45.55316 1.000 37.03452  ? 736 HOH A O     1 
HETATM 3435 O  O     . HOH F 5 .   ? -3.22989  -1.82068  23.48947 1.000 34.26944  ? 737 HOH A O     1 
HETATM 3436 O  O     . HOH F 5 .   ? 4.62027   -8.83561  15.68044 1.000 39.74532  ? 738 HOH A O     1 
HETATM 3437 O  O     . HOH F 5 .   ? -9.09848  0.32960   7.48906  1.000 20.40616  ? 739 HOH A O     1 
HETATM 3438 O  O     . HOH F 5 .   ? -6.91571  -30.19548 18.36272 1.000 52.97079  ? 740 HOH A O     1 
HETATM 3439 O  O     . HOH F 5 .   ? -6.70785  -9.21353  27.71946 1.000 39.03245  ? 741 HOH A O     1 
HETATM 3440 O  O     . HOH F 5 .   ? -19.07456 -1.70137  67.33281 1.000 61.39701  ? 742 HOH A O     1 
HETATM 3441 O  O     . HOH F 5 .   ? -14.65381 3.25004   60.23606 1.000 45.78488  ? 743 HOH A O     1 
HETATM 3442 O  O     . HOH F 5 .   ? -22.92397 -26.50383 34.34015 1.000 56.40001  ? 744 HOH A O     1 
HETATM 3443 O  O     . HOH F 5 .   ? 4.67978   -9.85450  10.76787 1.000 46.59269  ? 745 HOH A O     1 
HETATM 3444 O  O     . HOH F 5 .   ? 5.45823   -25.21652 54.56871 1.000 44.90422  ? 746 HOH A O     1 
HETATM 3445 O  O     . HOH F 5 .   ? -22.17301 -21.56759 19.95984 1.000 59.99557  ? 747 HOH A O     1 
HETATM 3446 O  O     . HOH F 5 .   ? -20.30977 -15.85915 24.51570 1.000 44.68119  ? 748 HOH A O     1 
HETATM 3447 O  O     . HOH F 5 .   ? -18.11870 -18.99247 59.06432 1.000 44.82366  ? 749 HOH A O     1 
HETATM 3448 O  O     . HOH F 5 .   ? 8.29101   -3.93065  57.74647 1.000 74.16186  ? 750 HOH A O     1 
HETATM 3449 O  O     . HOH F 5 .   ? -0.44441  -21.82196 57.70769 1.000 52.27548  ? 751 HOH A O     1 
HETATM 3450 O  O     . HOH F 5 .   ? -5.39078  -31.36812 21.46752 1.000 47.51997  ? 752 HOH A O     1 
HETATM 3451 O  O     . HOH F 5 .   ? -22.21622 -16.33798 26.75285 1.000 47.50978  ? 753 HOH A O     1 
HETATM 3452 O  O     . HOH F 5 .   ? -7.16467  -22.37089 60.64904 1.000 51.66343  ? 754 HOH A O     1 
HETATM 3453 O  O     . HOH F 5 .   ? -4.73549  -6.73286  27.05283 1.000 47.28078  ? 755 HOH A O     1 
HETATM 3454 O  O     . HOH F 5 .   ? 1.18146   -2.13937  27.41970 1.000 34.65832  ? 756 HOH A O     1 
HETATM 3455 O  O     . HOH F 5 .   ? -3.34214  -3.10475  25.89686 1.000 38.88445  ? 757 HOH A O     1 
HETATM 3456 O  O     . HOH F 5 .   ? -16.88295 4.09943   15.95690 1.000 44.30415  ? 758 HOH A O     1 
HETATM 3457 O  O     . HOH F 5 .   ? 1.71050   -25.36498 29.66238 1.000 40.06045  ? 759 HOH A O     1 
HETATM 3458 O  O     . HOH F 5 .   ? 10.56409  -5.82168  43.82617 1.000 47.49640  ? 760 HOH A O     1 
HETATM 3459 O  O     . HOH F 5 .   ? -18.87127 -16.94083 57.60178 1.000 39.97517  ? 761 HOH A O     1 
HETATM 3460 O  O     . HOH F 5 .   ? 9.38648   -23.64793 36.50081 1.000 50.79137  ? 762 HOH A O     1 
HETATM 3461 O  O     . HOH F 5 .   ? -3.48490  -35.03571 51.50945 1.000 45.75267  ? 763 HOH A O     1 
HETATM 3462 O  O     . HOH F 5 .   ? 4.01819   -8.55654  12.85262 1.000 45.03813  ? 764 HOH A O     1 
HETATM 3463 O  O     . HOH F 5 .   ? -10.34046 -35.26940 31.32908 1.000 36.49090  ? 765 HOH A O     1 
HETATM 3464 O  O     . HOH F 5 .   ? 0.10987   -21.99032 25.60802 1.000 51.91794  ? 766 HOH A O     1 
HETATM 3465 O  O     . HOH F 5 .   ? 8.04338   -24.94110 40.55831 1.000 42.13411  ? 767 HOH A O     1 
HETATM 3466 O  O     . HOH F 5 .   ? 0.83996   -22.67708 28.69052 1.000 46.07594  ? 768 HOH A O     1 
HETATM 3467 O  O     . HOH F 5 .   ? 0.07827   -3.22395  21.36315 1.000 27.77861  ? 769 HOH A O     1 
HETATM 3468 O  O     . HOH F 5 .   ? 6.04617   -24.49519 33.33737 1.000 37.97262  ? 770 HOH A O     1 
HETATM 3469 O  O     . HOH F 5 .   ? 1.19247   -19.72469 57.69187 1.000 48.86041  ? 771 HOH A O     1 
HETATM 3470 O  O     . HOH F 5 .   ? -9.96745  -4.47644  46.77740 1.000 37.83033  ? 772 HOH A O     1 
HETATM 3471 O  O     . HOH F 5 .   ? -14.89403 -35.36635 48.20878 1.000 52.01034  ? 773 HOH A O     1 
HETATM 3472 O  O     . HOH F 5 .   ? -12.86054 -13.59860 -1.40671 1.000 49.60616  ? 774 HOH A O     1 
HETATM 3473 O  O     . HOH F 5 .   ? -19.45999 -8.38784  -1.58548 1.000 59.11907  ? 775 HOH A O     1 
HETATM 3474 O  O     . HOH F 5 .   ? 9.17768   -25.74377 42.70138 1.000 49.43346  ? 776 HOH A O     1 
HETATM 3475 O  O     . HOH F 5 .   ? 2.68899   -7.08199  33.61343 1.000 53.87160  ? 777 HOH A O     1 
HETATM 3476 O  O     . HOH F 5 .   ? -11.87684 2.00483   21.27993 1.000 41.63182  ? 778 HOH A O     1 
HETATM 3477 O  O     . HOH F 5 .   ? -11.44476 -37.81489 49.20170 1.000 56.60581  ? 779 HOH A O     1 
HETATM 3478 O  O     . HOH F 5 .   ? 13.46591  -19.84790 59.50155 1.000 51.20103  ? 780 HOH A O     1 
HETATM 3479 O  O     . HOH F 5 .   ? 4.62469   -13.63192 18.78660 1.000 39.66991  ? 781 HOH A O     1 
HETATM 3480 O  O     . HOH F 5 .   ? 6.77526   -15.11153 22.41594 1.000 48.34386  ? 782 HOH A O     1 
HETATM 3481 O  O     . HOH F 5 .   ? -0.98954  -5.12314  42.20460 1.000 60.31791  ? 783 HOH A O     1 
HETATM 3482 O  O     . HOH F 5 .   ? -19.61778 -12.43393 35.56243 1.000 48.21738  ? 784 HOH A O     1 
HETATM 3483 O  O     . HOH F 5 .   ? 12.37695  -6.41418  41.15082 1.000 57.03224  ? 785 HOH A O     1 
HETATM 3484 O  O     . HOH F 5 .   ? -16.14947 -15.32368 0.81887  1.000 52.58975  ? 786 HOH A O     1 
HETATM 3485 O  O     . HOH F 5 .   ? -10.26387 2.38233   19.17045 1.000 39.03607  ? 787 HOH A O     1 
HETATM 3486 O  O     . HOH F 5 .   ? 4.23846   -26.74632 52.96161 1.000 40.91605  ? 788 HOH A O     1 
HETATM 3487 O  O     . HOH F 5 .   ? -8.80076  -3.39799  48.62411 1.000 32.30588  ? 789 HOH A O     1 
HETATM 3488 O  O     . HOH F 5 .   ? -23.65908 -15.38512 32.61261 1.000 52.26808  ? 790 HOH A O     1 
HETATM 3489 O  O     . HOH F 5 .   ? -20.99984 -6.85022  45.58798 1.000 44.73825  ? 791 HOH A O     1 
HETATM 3490 O  O     . HOH F 5 .   ? -22.12211 -27.13633 47.76242 1.000 50.68482  ? 792 HOH A O     1 
HETATM 3491 O  O     . HOH F 5 .   ? -5.75742  -5.81839  44.45657 1.000 50.46321  ? 793 HOH A O     1 
HETATM 3492 O  O     . HOH F 5 .   ? -1.77071  -36.51269 49.08823 1.000 42.98714  ? 794 HOH A O     1 
HETATM 3493 O  O     . HOH F 5 .   ? -8.98742  -35.56505 26.68404 1.000 47.33609  ? 795 HOH A O     1 
HETATM 3494 O  O     . HOH F 5 .   ? -12.59985 -14.85461 -3.49105 1.000 56.80747  ? 796 HOH A O     1 
HETATM 3495 O  O     . HOH F 5 .   ? -11.74729 -6.44269  26.82756 1.000 48.29347  ? 797 HOH A O     1 
HETATM 3496 O  O     . HOH F 5 .   ? -25.41829 0.52282   19.41845 1.000 52.23626  ? 798 HOH A O     1 
HETATM 3497 O  O     . HOH F 5 .   ? 11.65200  -20.94879 57.66758 1.000 44.38677  ? 799 HOH A O     1 
HETATM 3498 O  O     . HOH F 5 .   ? 2.47551   -7.01217  12.01120 1.000 45.82225  ? 800 HOH A O     1 
HETATM 3499 O  O     . HOH F 5 .   ? -1.23758  -26.10406 25.61152 1.000 45.45929  ? 801 HOH A O     1 
HETATM 3500 O  O     . HOH F 5 .   ? 0.17496   -24.42766 21.59380 1.000 56.61433  ? 802 HOH A O     1 
HETATM 3501 O  O     . HOH F 5 .   ? 4.49705   -21.67124 56.19486 1.000 47.50886  ? 803 HOH A O     1 
HETATM 3502 O  O     . HOH F 5 .   ? -6.17741  0.66688   8.05655  1.000 38.61805  ? 804 HOH A O     1 
HETATM 3503 O  O     . HOH F 5 .   ? 7.86341   -27.90841 42.38176 1.000 32.45633  ? 805 HOH A O     1 
HETATM 3504 O  O     . HOH F 5 .   ? -4.16757  -35.32324 47.56758 1.000 39.36446  ? 806 HOH A O     1 
HETATM 3505 O  O     . HOH F 5 .   ? -4.44623  -20.54419 61.04709 1.000 60.62055  ? 807 HOH A O     1 
HETATM 3506 O  O     . HOH F 5 .   ? -24.76824 -14.43738 28.69959 1.000 54.28646  ? 808 HOH A O     1 
HETATM 3507 O  O     . HOH F 5 .   ? -4.21598  0.54643   10.36291 1.000 40.64234  ? 809 HOH A O     1 
HETATM 3508 O  O     . HOH F 5 .   ? 10.71550  -21.48269 39.84982 1.000 51.58711  ? 810 HOH A O     1 
HETATM 3509 O  O     . HOH F 5 .   ? -16.72031 -18.23166 4.97561  1.000 51.18946  ? 811 HOH A O     1 
HETATM 3510 O  O     . HOH F 5 .   ? -1.95893  -2.48006  27.72806 1.000 43.21200  ? 812 HOH A O     1 
HETATM 3511 O  O     . HOH F 5 .   ? 5.23825   -29.16946 52.80395 1.000 52.77314  ? 813 HOH A O     1 
HETATM 3512 O  O     . HOH G 5 .   ? -12.24846 -34.65732 42.78800 1.000 44.60468  ? 101 HOH B O     1 
HETATM 3513 O  O     . HOH G 5 .   ? 4.43475   -31.10199 27.68725 1.000 62.59014  ? 102 HOH B O     1 
HETATM 3514 O  O     . HOH G 5 .   ? -0.95355  -37.63354 30.10179 1.000 51.17925  ? 103 HOH B O     1 
HETATM 3515 O  O     . HOH G 5 .   ? -11.34681 -35.15495 33.94919 1.000 28.82691  ? 104 HOH B O     1 
HETATM 3516 O  O     . HOH G 5 .   ? -7.63331  -37.26243 31.57776 1.000 32.83194  ? 105 HOH B O     1 
HETATM 3517 O  O     . HOH G 5 .   ? -0.78360  -38.82863 33.83545 1.000 41.65405  ? 106 HOH B O     1 
HETATM 3518 O  O     . HOH G 5 .   ? -3.16299  -34.26663 43.05595 1.000 37.62684  ? 107 HOH B O     1 
HETATM 3519 O  O     . HOH G 5 .   ? -6.06125  -31.92196 43.46615 1.000 35.24300  ? 108 HOH B O     1 
HETATM 3520 O  O     . HOH G 5 .   ? -10.58425 -36.55027 37.87549 1.000 36.99538  ? 109 HOH B O     1 
HETATM 3521 O  O     . HOH G 5 .   ? -1.56438  -31.99918 28.32330 1.000 49.69452  ? 110 HOH B O     1 
HETATM 3522 O  O     . HOH G 5 .   ? -0.49198  -39.47768 45.44752 1.000 27.05232  ? 111 HOH B O     1 
HETATM 3523 O  O     . HOH G 5 .   ? -9.27840  -32.92263 30.14727 1.000 34.45303  ? 112 HOH B O     1 
HETATM 3524 O  O     . HOH G 5 .   ? -14.99639 -37.41106 47.55179 1.000 46.02033  ? 113 HOH B O     1 
HETATM 3525 O  O     . HOH G 5 .   ? -11.60756 -28.77265 28.03933 1.000 51.71671  ? 114 HOH B O     1 
HETATM 3526 O  O     . HOH G 5 .   ? -4.85048  -37.06607 30.17707 1.000 36.30560  ? 115 HOH B O     1 
HETATM 3527 O  O     . HOH G 5 .   ? -7.68983  -34.08610 28.49670 1.000 43.63434  ? 116 HOH B O     1 
HETATM 3528 O  O     . HOH G 5 .   ? -11.52208 -31.91775 28.62603 1.000 43.01638  ? 117 HOH B O     1 
HETATM 3529 O  O     . HOH G 5 .   ? -4.98511  -35.34755 28.89377 1.000 45.47075  ? 118 HOH B O     1 
HETATM 3530 O  O     . HOH G 5 .   ? -13.20647 -39.14386 49.24409 1.000 53.42502  ? 119 HOH B O     1 
HETATM 3531 O  O     . HOH G 5 .   ? -13.56918 -36.21245 34.33612 1.000 47.28859  ? 120 HOH B O     1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N  N     . GLN A 11  ? 1.12231 0.88208 0.82095 -0.05291 -0.06765 -0.05503 4   GLN A N     
2    C  CA    . GLN A 11  ? 1.05195 0.84649 0.79180 -0.05142 -0.06995 -0.04997 4   GLN A CA    
3    C  C     . GLN A 11  ? 1.00251 0.81806 0.76043 -0.04523 -0.06505 -0.04600 4   GLN A C     
4    O  O     . GLN A 11  ? 1.05943 0.86717 0.80129 -0.04587 -0.06672 -0.04479 4   GLN A O     
5    C  CB    . GLN A 11  ? 1.11325 0.91705 0.86381 -0.06239 -0.08791 -0.04541 4   GLN A CB    
6    C  CG    . GLN A 11  ? 1.27630 1.05878 1.00924 -0.06973 -0.09361 -0.04895 4   GLN A CG    
7    C  CD    . GLN A 11  ? 1.34484 1.14251 1.10365 -0.06742 -0.08941 -0.04888 4   GLN A CD    
8    O  OE1   . GLN A 11  ? 1.31287 1.10019 1.06611 -0.06090 -0.07737 -0.05374 4   GLN A OE1   
9    N  NE2   . GLN A 11  ? 1.33507 1.15683 1.12181 -0.07255 -0.09914 -0.04290 4   GLN A NE2   
10   N  N     . ILE A 12  ? 0.83087 0.67166 0.62107 -0.03951 -0.05922 -0.04395 5   ILE A N     
11   C  CA    . ILE A 12  ? 0.89909 0.75956 0.70800 -0.03348 -0.05404 -0.04038 5   ILE A CA    
12   C  C     . ILE A 12  ? 0.87839 0.74610 0.68885 -0.03832 -0.06604 -0.03505 5   ILE A C     
13   O  O     . ILE A 12  ? 0.83568 0.70740 0.64600 -0.03470 -0.06268 -0.03286 5   ILE A O     
14   C  CB    . ILE A 12  ? 0.77333 0.65795 0.61518 -0.02859 -0.04911 -0.03887 5   ILE A CB    
15   C  CG1   . ILE A 12  ? 0.74682 0.62351 0.58662 -0.02420 -0.03866 -0.04351 5   ILE A CG1   
16   C  CG2   . ILE A 12  ? 0.69878 0.60037 0.55730 -0.02253 -0.04331 -0.03575 5   ILE A CG2   
17   C  CD1   . ILE A 12  ? 0.70077 0.59710 0.56674 -0.01711 -0.02983 -0.04245 5   ILE A CD1   
18   N  N     . ARG A 13  ? 1.06191 0.93150 0.87435 -0.04668 -0.08040 -0.03224 6   ARG A N     
19   C  CA    . ARG A 13  ? 1.11787 0.99427 0.93195 -0.05138 -0.09290 -0.02623 6   ARG A CA    
20   C  C     . ARG A 13  ? 1.04147 0.89436 0.82191 -0.05389 -0.09506 -0.02752 6   ARG A C     
21   O  O     . ARG A 13  ? 1.12877 0.98683 0.90935 -0.05381 -0.09981 -0.02295 6   ARG A O     
22   C  CB    . ARG A 13  ? 1.14674 1.03075 0.97120 -0.06042 -0.10802 -0.02208 6   ARG A CB    
23   C  CG    . ARG A 13  ? 1.18982 1.10265 1.05147 -0.05753 -0.10748 -0.01782 6   ARG A CG    
24   C  CD    . ARG A 13  ? 1.07133 1.00105 0.95112 -0.04780 -0.09806 -0.01600 6   ARG A CD    
25   N  NE    . ARG A 13  ? 1.02439 0.97712 0.93507 -0.04375 -0.09466 -0.01348 6   ARG A NE    
26   C  CZ    . ARG A 13  ? 0.94886 0.92072 0.88156 -0.04573 -0.10278 -0.00676 6   ARG A CZ    
27   N  NH1   . ARG A 13  ? 0.95859 0.93189 0.88903 -0.05201 -0.11592 -0.00112 6   ARG A NH1   
28   N  NH2   . ARG A 13  ? 0.92513 0.91512 0.88268 -0.04115 -0.09750 -0.00516 6   ARG A NH2   
29   N  N     . ASN A 14  ? 0.97860 0.80428 0.72872 -0.05564 -0.09114 -0.03357 7   ASN A N     
30   C  CA    . ASN A 14  ? 0.93864 0.73897 0.65315 -0.05705 -0.09082 -0.03541 7   ASN A CA    
31   C  C     . ASN A 14  ? 0.95968 0.75746 0.66933 -0.04723 -0.07362 -0.03749 7   ASN A C     
32   O  O     . ASN A 14  ? 0.81971 0.59997 0.50284 -0.04729 -0.07193 -0.03777 7   ASN A O     
33   C  CB    . ASN A 14  ? 1.04598 0.81457 0.72606 -0.06316 -0.09385 -0.04105 7   ASN A CB    
34   C  CG    . ASN A 14  ? 1.24702 1.01005 0.91964 -0.07358 -0.11075 -0.03621 7   ASN A CG    
35   O  OD1   . ASN A 14  ? 1.26993 1.02862 0.94403 -0.07986 -0.11749 -0.03598 7   ASN A OD1   
36   N  ND2   . ASN A 14  ? 1.15396 0.91837 0.82115 -0.07505 -0.11683 -0.03138 7   ASN A ND2   
37   N  N     . MET A 15  ? 0.83144 0.64606 0.56564 -0.03927 -0.06116 -0.03841 8   MET A N     
38   C  CA    . MET A 15  ? 0.71469 0.52910 0.44750 -0.03068 -0.04517 -0.03939 8   MET A CA    
39   C  C     . MET A 15  ? 0.71784 0.55468 0.47391 -0.02733 -0.04458 -0.03396 8   MET A C     
40   O  O     . MET A 15  ? 0.66375 0.49929 0.41604 -0.02212 -0.03377 -0.03339 8   MET A O     
41   C  CB    . MET A 15  ? 0.71871 0.53632 0.46275 -0.02396 -0.03153 -0.04322 8   MET A CB    
42   C  CG    . MET A 15  ? 0.71180 0.50905 0.43744 -0.02660 -0.03217 -0.04845 8   MET A CG    
43   S  SD    . MET A 15  ? 0.67330 0.47811 0.41755 -0.01861 -0.01837 -0.05157 8   MET A SD    
44   C  CE    . MET A 15  ? 0.67617 0.44332 0.38082 -0.01859 -0.01286 -0.05829 8   MET A CE    
45   N  N     . VAL A 16  ? 0.66695 0.52371 0.44675 -0.03001 -0.05536 -0.02963 9   VAL A N     
46   C  CA    . VAL A 16  ? 0.60460 0.48142 0.40687 -0.02596 -0.05401 -0.02487 9   VAL A CA    
47   C  C     . VAL A 16  ? 0.58732 0.47364 0.39749 -0.03063 -0.06917 -0.01906 9   VAL A C     
48   O  O     . VAL A 16  ? 0.68027 0.56485 0.48824 -0.03702 -0.08085 -0.01818 9   VAL A O     
49   C  CB    . VAL A 16  ? 0.59975 0.49620 0.43150 -0.02052 -0.04619 -0.02548 9   VAL A CB    
50   C  CG1   . VAL A 16  ? 0.53782 0.45033 0.39153 -0.02326 -0.05575 -0.02338 9   VAL A CG1   
51   C  CG2   . VAL A 16  ? 0.58548 0.49289 0.42978 -0.01518 -0.03897 -0.02271 9   VAL A CG2   
52   N  N     . GLU A 17  ? 0.65825 0.55421 0.47751 -0.02745 -0.06897 -0.01453 10  GLU A N     
53   C  CA    . GLU A 17  ? 0.73809 0.64827 0.57260 -0.02888 -0.08068 -0.00792 10  GLU A CA    
54   C  C     . GLU A 17  ? 0.48829 0.42142 0.35550 -0.02507 -0.07932 -0.00632 10  GLU A C     
55   O  O     . GLU A 17  ? 0.54237 0.48454 0.42289 -0.01908 -0.07120 -0.00577 10  GLU A O     
56   C  CB    . GLU A 17  ? 0.69375 0.60216 0.52262 -0.02602 -0.07949 -0.00389 10  GLU A CB    
57   C  CG    . GLU A 17  ? 0.89709 0.81232 0.73094 -0.02831 -0.09327 0.00342  10  GLU A CG    
58   C  CD    . GLU A 17  ? 0.83283 0.73496 0.64609 -0.03662 -0.10660 0.00459  10  GLU A CD    
59   O  OE1   . GLU A 17  ? 0.82483 0.73841 0.65213 -0.04049 -0.11859 0.00872  10  GLU A OE1   
60   O  OE2   . GLU A 17  ? 0.93613 0.81609 0.71875 -0.03947 -0.10500 0.00167  10  GLU A OE2   
61   N  N     . PRO A 18  ? 0.54097 0.48314 0.42085 -0.02864 -0.08705 -0.00520 11  PRO A N     
62   C  CA    . PRO A 18  ? 0.44894 0.41151 0.35801 -0.02455 -0.08413 -0.00387 11  PRO A CA    
63   C  C     . PRO A 18  ? 0.50187 0.47865 0.42791 -0.01935 -0.08511 0.00194  11  PRO A C     
64   O  O     . PRO A 18  ? 0.47605 0.45336 0.39921 -0.02081 -0.09389 0.00738  11  PRO A O     
65   C  CB    . PRO A 18  ? 0.57971 0.54784 0.49621 -0.03076 -0.09417 -0.00210 11  PRO A CB    
66   C  CG    . PRO A 18  ? 0.62524 0.57831 0.51895 -0.03849 -0.10545 -0.00073 11  PRO A CG    
67   C  CD    . PRO A 18  ? 0.66363 0.59629 0.53037 -0.03706 -0.09829 -0.00521 11  PRO A CD    
68   N  N     . MET A 19  ? 0.35363 0.34044 0.29605 -0.01311 -0.07617 0.00090  12  MET A N     
69   C  CA    . MET A 19  ? 0.39609 0.39272 0.35161 -0.00751 -0.07581 0.00570  12  MET A CA    
70   C  C     . MET A 19  ? 0.31698 0.33027 0.29322 -0.00659 -0.08324 0.01177  12  MET A C     
71   O  O     . MET A 19  ? 0.34807 0.36829 0.33298 -0.00994 -0.08684 0.01193  12  MET A O     
72   C  CB    . MET A 19  ? 0.43233 0.43163 0.39589 -0.00165 -0.06445 0.00277  12  MET A CB    
73   C  CG    . MET A 19  ? 0.38815 0.39988 0.37101 0.00102  -0.06082 0.00157  12  MET A CG    
74   S  SD    . MET A 19  ? 0.36841 0.37981 0.35626 0.00599  -0.04889 -0.00242 12  MET A SD    
75   C  CE    . MET A 19  ? 0.29799 0.29713 0.27016 0.00291  -0.04238 -0.00812 12  MET A CE    
76   N  N     . ASP A 20  ? 0.33828 0.35773 0.32260 -0.00169 -0.08500 0.01731  13  ASP A N     
77   C  CA    . ASP A 20  ? 0.30280 0.33916 0.30866 0.00131  -0.09011 0.02419  13  ASP A CA    
78   C  C     . ASP A 20  ? 0.30355 0.35069 0.32696 0.00543  -0.08242 0.02219  13  ASP A C     
79   O  O     . ASP A 20  ? 0.30233 0.34454 0.32329 0.00892  -0.07292 0.01716  13  ASP A O     
80   C  CB    . ASP A 20  ? 0.36758 0.40538 0.37642 0.00751  -0.09124 0.02999  13  ASP A CB    
81   C  CG    . ASP A 20  ? 0.35474 0.40998 0.38552 0.01147  -0.09689 0.03864  13  ASP A CG    
82   O  OD1   . ASP A 20  ? 0.40681 0.46470 0.43754 0.00971  -0.10706 0.04548  13  ASP A OD1   
83   O  OD2   . ASP A 20  ? 0.37864 0.44492 0.42679 0.01691  -0.09082 0.03920  13  ASP A OD2   
84   N  N     . PRO A 21  ? 0.29249 0.35426 0.33349 0.00464  -0.08649 0.02646  14  PRO A N     
85   C  CA    . PRO A 21  ? 0.30312 0.37434 0.35946 0.00876  -0.07867 0.02495  14  PRO A CA    
86   C  C     . PRO A 21  ? 0.30690 0.37947 0.36945 0.01826  -0.07032 0.02546  14  PRO A C     
87   O  O     . PRO A 21  ? 0.28700 0.35835 0.35152 0.02114  -0.06196 0.02101  14  PRO A O     
88   C  CB    . PRO A 21  ? 0.34845 0.43647 0.42360 0.00654  -0.08553 0.03203  14  PRO A CB    
89   C  CG    . PRO A 21  ? 0.33549 0.41966 0.40129 -0.00194 -0.09783 0.03476  14  PRO A CG    
90   C  CD    . PRO A 21  ? 0.36625 0.43669 0.41396 -0.00059 -0.09868 0.03347  14  PRO A CD    
91   N  N     . ARG A 22  ? 0.25929 0.33322 0.32411 0.02314  -0.07282 0.03104  15  ARG A N     
92   C  CA    . ARG A 22  ? 0.26084 0.33212 0.32811 0.03211  -0.06495 0.03116  15  ARG A CA    
93   C  C     . ARG A 22  ? 0.28846 0.34356 0.33844 0.03124  -0.05917 0.02413  15  ARG A C     
94   O  O     . ARG A 22  ? 0.28052 0.33161 0.33070 0.03568  -0.05146 0.02106  15  ARG A O     
95   C  CB    . ARG A 22  ? 0.27514 0.35015 0.34794 0.03779  -0.06923 0.03919  15  ARG A CB    
96   C  CG    . ARG A 22  ? 0.47897 0.54608 0.54938 0.04701  -0.06161 0.03913  15  ARG A CG    
97   C  CD    . ARG A 22  ? 0.61777 0.69467 0.70466 0.05593  -0.05500 0.04234  15  ARG A CD    
98   N  NE    . ARG A 22  ? 0.71196 0.78033 0.79600 0.06553  -0.04956 0.04421  15  ARG A NE    
99   C  CZ    . ARG A 22  ? 0.70441 0.77083 0.78819 0.07017  -0.05335 0.05039  15  ARG A CZ    
100  N  NH1   . ARG A 22  ? 0.61199 0.68532 0.69862 0.06603  -0.06337 0.05588  15  ARG A NH1   
101  N  NH2   . ARG A 22  ? 0.58906 0.64503 0.66852 0.07916  -0.04735 0.05129  15  ARG A NH2   
102  N  N     . THR A 23  ? 0.30026 0.34556 0.33472 0.02526  -0.06283 0.02190  16  THR A N     
103  C  CA    . THR A 23  ? 0.27130 0.30332 0.29135 0.02378  -0.05684 0.01604  16  THR A CA    
104  C  C     . THR A 23  ? 0.25393 0.28674 0.27651 0.02226  -0.05051 0.01005  16  THR A C     
105  O  O     . THR A 23  ? 0.22875 0.25619 0.24901 0.02425  -0.04394 0.00677  16  THR A O     
106  C  CB    . THR A 23  ? 0.29081 0.31273 0.29362 0.01781  -0.06098 0.01515  16  THR A CB    
107  O  OG1   . THR A 23  ? 0.26372 0.28490 0.26391 0.01902  -0.06791 0.02134  16  THR A OG1   
108  C  CG2   . THR A 23  ? 0.27477 0.28461 0.26480 0.01698  -0.05386 0.01069  16  THR A CG2   
109  N  N     . PHE A 24  ? 0.21202 0.25131 0.23963 0.01844  -0.05302 0.00904  17  PHE A N     
110  C  CA    . PHE A 24  ? 0.22562 0.26528 0.25543 0.01717  -0.04742 0.00382  17  PHE A CA    
111  C  C     . PHE A 24  ? 0.19908 0.24495 0.24089 0.02289  -0.04222 0.00421  17  PHE A C     
112  O  O     . PHE A 24  ? 0.24297 0.28391 0.28222 0.02416  -0.03631 0.00042  17  PHE A O     
113  C  CB    . PHE A 24  ? 0.21032 0.25366 0.24150 0.01159  -0.05170 0.00302  17  PHE A CB    
114  C  CG    . PHE A 24  ? 0.22574 0.27026 0.26075 0.01092  -0.04642 -0.00138 17  PHE A CG    
115  C  CD1   . PHE A 24  ? 0.24812 0.28342 0.27297 0.00912  -0.04164 -0.00668 17  PHE A CD1   
116  C  CD2   . PHE A 24  ? 0.27993 0.33503 0.32909 0.01250  -0.04581 0.00042  17  PHE A CD2   
117  C  CE1   . PHE A 24  ? 0.27001 0.30651 0.29891 0.00887  -0.03725 -0.01011 17  PHE A CE1   
118  C  CE2   . PHE A 24  ? 0.28376 0.33907 0.33546 0.01182  -0.04123 -0.00334 17  PHE A CE2   
119  C  CZ    . PHE A 24  ? 0.26048 0.30633 0.30198 0.01002  -0.03742 -0.00859 17  PHE A CZ    
120  N  N     . VAL A 25  ? 0.22379 0.28018 0.27842 0.02645  -0.04428 0.00925  18  VAL A N     
121  C  CA    . VAL A 25  ? 0.22864 0.28992 0.29302 0.03217  -0.03840 0.00959  18  VAL A CA    
122  C  C     . VAL A 25  ? 0.26874 0.32027 0.32659 0.03755  -0.03336 0.00838  18  VAL A C     
123  O  O     . VAL A 25  ? 0.24270 0.29055 0.29973 0.03977  -0.02779 0.00530  18  VAL A O     
124  C  CB    . VAL A 25  ? 0.25878 0.33418 0.33911 0.03560  -0.04072 0.01645  18  VAL A CB    
125  C  CG1   . VAL A 25  ? 0.42404 0.50190 0.51156 0.04325  -0.03319 0.01735  18  VAL A CG1   
126  C  CG2   . VAL A 25  ? 0.26128 0.34578 0.34867 0.02902  -0.04525 0.01722  18  VAL A CG2   
127  N  N     . SER A 26  ? 0.21179 0.25756 0.26354 0.03913  -0.03579 0.01087  19  SER A N     
128  C  CA    . SER A 26  ? 0.23359 0.26839 0.27830 0.04379  -0.03158 0.01014  19  SER A CA    
129  C  C     . SER A 26  ? 0.28495 0.30934 0.31870 0.03915  -0.02885 0.00457  19  SER A C     
130  O  O     . SER A 26  ? 0.26648 0.28292 0.29616 0.04125  -0.02476 0.00249  19  SER A O     
131  C  CB    . SER A 26  ? 0.26346 0.29451 0.30483 0.04691  -0.03510 0.01506  19  SER A CB    
132  O  OG    . SER A 26  ? 0.28041 0.30745 0.31262 0.04088  -0.03979 0.01473  19  SER A OG    
133  N  N     . ASN A 27  ? 0.22701 0.25101 0.25578 0.03284  -0.03097 0.00246  20  ASN A N     
134  C  CA    . ASN A 27  ? 0.21118 0.22728 0.23163 0.02879  -0.02794 -0.00147 20  ASN A CA    
135  C  C     . ASN A 27  ? 0.21619 0.23559 0.24070 0.02658  -0.02478 -0.00551 20  ASN A C     
136  O  O     . ASN A 27  ? 0.20892 0.22324 0.23005 0.02462  -0.02175 -0.00789 20  ASN A O     
137  C  CB    . ASN A 27  ? 0.22745 0.24004 0.23900 0.02411  -0.03022 -0.00139 20  ASN A CB    
138  C  CG    . ASN A 27  ? 0.25177 0.25661 0.25523 0.02523  -0.03194 0.00194  20  ASN A CG    
139  O  OD1   . ASN A 27  ? 0.28964 0.29558 0.29118 0.02571  -0.03689 0.00546  20  ASN A OD1   
140  N  ND2   . ASN A 27  ? 0.21512 0.21175 0.21371 0.02520  -0.02856 0.00135  20  ASN A ND2   
141  N  N     . PHE A 28  ? 0.18746 0.21540 0.21953 0.02638  -0.02583 -0.00577 21  PHE A N     
142  C  CA    . PHE A 28  ? 0.19874 0.22912 0.23401 0.02431  -0.02314 -0.00925 21  PHE A CA    
143  C  C     . PHE A 28  ? 0.20066 0.23454 0.24289 0.02802  -0.02074 -0.00923 21  PHE A C     
144  O  O     . PHE A 28  ? 0.19329 0.22857 0.23776 0.02657  -0.01872 -0.01176 21  PHE A O     
145  C  CB    . PHE A 28  ? 0.19028 0.22475 0.22613 0.02034  -0.02559 -0.01014 21  PHE A CB    
146  C  CG    . PHE A 28  ? 0.21791 0.24573 0.24376 0.01659  -0.02524 -0.01198 21  PHE A CG    
147  C  CD1   . PHE A 28  ? 0.23868 0.26229 0.25656 0.01547  -0.02841 -0.00994 21  PHE A CD1   
148  C  CD2   . PHE A 28  ? 0.22978 0.25521 0.25392 0.01477  -0.02122 -0.01519 21  PHE A CD2   
149  C  CE1   . PHE A 28  ? 0.28132 0.29740 0.28798 0.01247  -0.02687 -0.01150 21  PHE A CE1   
150  C  CE2   . PHE A 28  ? 0.24011 0.25939 0.25518 0.01240  -0.01920 -0.01638 21  PHE A CE2   
151  C  CZ    . PHE A 28  ? 0.26205 0.27608 0.26748 0.01123  -0.02164 -0.01472 21  PHE A CZ    
152  N  N     . ASN A 29  ? 0.24415 0.27864 0.28904 0.03324  -0.02041 -0.00620 22  ASN A N     
153  C  CA    . ASN A 29  ? 0.26480 0.29914 0.31263 0.03758  -0.01658 -0.00636 22  ASN A CA    
154  C  C     . ASN A 29  ? 0.25635 0.28203 0.29730 0.03562  -0.01426 -0.01024 22  ASN A C     
155  O  O     . ASN A 29  ? 0.25129 0.26865 0.28495 0.03385  -0.01477 -0.01115 22  ASN A O     
156  C  CB    . ASN A 29  ? 0.25637 0.28782 0.30400 0.04448  -0.01518 -0.00284 22  ASN A CB    
157  C  CG    . ASN A 29  ? 0.42102 0.45079 0.46964 0.04988  -0.01008 -0.00284 22  ASN A CG    
158  O  OD1   . ASN A 29  ? 0.32493 0.34330 0.36417 0.05034  -0.00766 -0.00581 22  ASN A OD1   
159  N  ND2   . ASN A 29  ? 0.41245 0.45330 0.47199 0.05352  -0.00854 0.00082  22  ASN A ND2   
160  N  N     . ASN A 30  ? 0.21406 0.24187 0.25758 0.03541  -0.01221 -0.01195 23  ASN A N     
161  C  CA    . ASN A 30  ? 0.19516 0.21660 0.23356 0.03229  -0.01161 -0.01504 23  ASN A CA    
162  C  C     . ASN A 30  ? 0.21963 0.23093 0.25056 0.03544  -0.00953 -0.01571 23  ASN A C     
163  O  O     . ASN A 30  ? 0.23431 0.24141 0.26180 0.03295  -0.00968 -0.01772 23  ASN A O     
164  C  CB    . ASN A 30  ? 0.19279 0.22082 0.23655 0.02896  -0.01163 -0.01667 23  ASN A CB    
165  C  CG    . ASN A 30  ? 0.20701 0.23975 0.25531 0.03159  -0.00956 -0.01596 23  ASN A CG    
166  O  OD1   . ASN A 30  ? 0.23371 0.26804 0.28382 0.03616  -0.00773 -0.01361 23  ASN A OD1   
167  N  ND2   . ASN A 30  ? 0.20651 0.24191 0.25732 0.02896  -0.00940 -0.01742 23  ASN A ND2   
168  N  N     . ARG A 31  ? 0.26902 0.27467 0.29590 0.04080  -0.00790 -0.01393 24  ARG A N     
169  C  CA    . ARG A 31  ? 0.27618 0.26730 0.29134 0.04340  -0.00604 -0.01516 24  ARG A CA    
170  C  C     . ARG A 31  ? 0.26410 0.24600 0.27178 0.03721  -0.00955 -0.01706 24  ARG A C     
171  O  O     . ARG A 31  ? 0.26995 0.25184 0.27808 0.03469  -0.01164 -0.01608 24  ARG A O     
172  C  CB    . ARG A 31  ? 0.29602 0.28029 0.30671 0.05076  -0.00331 -0.01279 24  ARG A CB    
173  C  CG    . ARG A 31  ? 0.30900 0.27436 0.30391 0.05388  -0.00090 -0.01452 24  ARG A CG    
174  C  CD    . ARG A 31  ? 0.42181 0.37933 0.41198 0.06281  0.00311  -0.01192 24  ARG A CD    
175  N  NE    . ARG A 31  ? 0.55778 0.50035 0.53464 0.06850  0.00828  -0.01326 24  ARG A NE    
176  C  CZ    . ARG A 31  ? 0.52727 0.44802 0.48517 0.06714  0.00738  -0.01617 24  ARG A CZ    
177  N  NH1   . ARG A 31  ? 0.40556 0.31839 0.35767 0.05998  0.00147  -0.01749 24  ARG A NH1   
178  N  NH2   . ARG A 31  ? 0.57599 0.48167 0.51957 0.07278  0.01257  -0.01753 24  ARG A NH2   
179  N  N     . PRO A 32  ? 0.27201 0.24696 0.27357 0.03406  -0.01064 -0.01911 25  PRO A N     
180  C  CA    . PRO A 32  ? 0.27734 0.24747 0.27596 0.02694  -0.01482 -0.01968 25  PRO A CA    
181  C  C     . PRO A 32  ? 0.32320 0.28035 0.31231 0.02614  -0.01636 -0.01888 25  PRO A C     
182  O  O     . PRO A 32  ? 0.30097 0.25970 0.29269 0.02078  -0.01888 -0.01775 25  PRO A O     
183  C  CB    . PRO A 32  ? 0.32439 0.28820 0.31703 0.02456  -0.01641 -0.02130 25  PRO A CB    
184  C  CG    . PRO A 32  ? 0.33790 0.31116 0.33683 0.02852  -0.01299 -0.02164 25  PRO A CG    
185  C  CD    . PRO A 32  ? 0.34328 0.31883 0.34393 0.03553  -0.00875 -0.02028 25  PRO A CD    
186  N  N     . ILE A 33  ? 0.31020 0.25375 0.28787 0.03153  -0.01438 -0.01914 26  ILE A N     
187  C  CA    . ILE A 33  ? 0.31796 0.24653 0.28480 0.03162  -0.01555 -0.01831 26  ILE A CA    
188  C  C     . ILE A 33  ? 0.37131 0.30446 0.34241 0.03883  -0.01231 -0.01601 26  ILE A C     
189  O  O     . ILE A 33  ? 0.34738 0.28036 0.31807 0.04678  -0.00805 -0.01549 26  ILE A O     
190  C  CB    . ILE A 33  ? 0.32030 0.22656 0.26836 0.03277  -0.01582 -0.02020 26  ILE A CB    
191  C  CG1   . ILE A 33  ? 0.36402 0.26744 0.30881 0.02515  -0.02032 -0.02188 26  ILE A CG1   
192  C  CG2   . ILE A 33  ? 0.33306 0.22139 0.26852 0.03195  -0.01761 -0.01934 26  ILE A CG2   
193  C  CD1   . ILE A 33  ? 0.34021 0.24939 0.29223 0.01532  -0.02595 -0.02024 26  ILE A CD1   
194  N  N     . LEU A 34  ? 0.31319 0.25113 0.28891 0.03614  -0.01424 -0.01398 27  LEU A N     
195  C  CA    . LEU A 34  ? 0.30817 0.25303 0.28964 0.04190  -0.01269 -0.01111 27  LEU A CA    
196  C  C     . LEU A 34  ? 0.34016 0.27646 0.31557 0.03962  -0.01495 -0.00906 27  LEU A C     
197  O  O     . LEU A 34  ? 0.30449 0.24546 0.28288 0.03278  -0.01727 -0.00866 27  LEU A O     
198  C  CB    . LEU A 34  ? 0.28033 0.24518 0.27637 0.04060  -0.01296 -0.01051 27  LEU A CB    
199  C  CG    . LEU A 34  ? 0.43303 0.40812 0.43704 0.04521  -0.01294 -0.00711 27  LEU A CG    
200  C  CD1   . LEU A 34  ? 0.48339 0.45425 0.48620 0.05448  -0.00995 -0.00452 27  LEU A CD1   
201  C  CD2   . LEU A 34  ? 0.29941 0.29116 0.31539 0.04327  -0.01342 -0.00738 27  LEU A CD2   
202  N  N     . SER A 35  ? 0.33840 0.26142 0.30481 0.04569  -0.01366 -0.00748 28  SER A N     
203  C  CA    . SER A 35  ? 0.35881 0.27045 0.31724 0.04414  -0.01569 -0.00523 28  SER A CA    
204  C  C     . SER A 35  ? 0.35586 0.27691 0.32133 0.04848  -0.01600 -0.00123 28  SER A C     
205  O  O     . SER A 35  ? 0.33801 0.27224 0.31372 0.05388  -0.01467 0.00019  28  SER A O     
206  C  CB    . SER A 35  ? 0.45537 0.34336 0.39720 0.04817  -0.01450 -0.00575 28  SER A CB    
207  O  OG    . SER A 35  ? 0.42487 0.30265 0.35818 0.04353  -0.01535 -0.00937 28  SER A OG    
208  N  N     . GLY A 36  ? 0.28776 0.20186 0.24759 0.04536  -0.01832 0.00111  29  GLY A N     
209  C  CA    . GLY A 36  ? 0.32324 0.24227 0.28615 0.04905  -0.01968 0.00542  29  GLY A CA    
210  C  C     . GLY A 36  ? 0.34370 0.27815 0.31462 0.04375  -0.02198 0.00629  29  GLY A C     
211  O  O     . GLY A 36  ? 0.34703 0.28440 0.31855 0.04574  -0.02421 0.01006  29  GLY A O     
212  N  N     . LEU A 37  ? 0.29464 0.23775 0.27049 0.03735  -0.02160 0.00314  30  LEU A N     
213  C  CA    . LEU A 37  ? 0.30113 0.25645 0.28224 0.03303  -0.02284 0.00348  30  LEU A CA    
214  C  C     . LEU A 37  ? 0.37192 0.32063 0.34565 0.02662  -0.02303 0.00475  30  LEU A C     
215  O  O     . LEU A 37  ? 0.51034 0.45507 0.48255 0.02130  -0.02169 0.00334  30  LEU A O     
216  C  CB    . LEU A 37  ? 0.30796 0.27494 0.29769 0.03037  -0.02150 -0.00009 30  LEU A CB    
217  C  CG    . LEU A 37  ? 0.28459 0.26035 0.28272 0.03597  -0.02109 -0.00057 30  LEU A CG    
218  C  CD1   . LEU A 37  ? 0.29918 0.28454 0.30445 0.03285  -0.01986 -0.00393 30  LEU A CD1   
219  C  CD2   . LEU A 37  ? 0.31552 0.29899 0.31806 0.03941  -0.02389 0.00310  30  LEU A CD2   
220  N  N     . ASP A 38  ? 0.39763 0.34557 0.36705 0.02679  -0.02484 0.00801  31  ASP A N     
221  C  CA    . ASP A 38  ? 0.48745 0.42853 0.44887 0.02112  -0.02416 0.00995  31  ASP A CA    
222  C  C     . ASP A 38  ? 0.47509 0.42488 0.43803 0.01609  -0.02226 0.00895  31  ASP A C     
223  O  O     . ASP A 38  ? 0.46348 0.40874 0.42005 0.01165  -0.02041 0.01097  31  ASP A O     
224  C  CB    . ASP A 38  ? 0.43343 0.36516 0.38595 0.02407  -0.02681 0.01457  31  ASP A CB    
225  C  CG    . ASP A 38  ? 0.56317 0.50282 0.51718 0.02736  -0.03031 0.01670  31  ASP A CG    
226  O  OD1   . ASP A 38  ? 0.54769 0.49944 0.50976 0.02783  -0.03094 0.01453  31  ASP A OD1   
227  O  OD2   . ASP A 38  ? 0.52304 0.45598 0.46969 0.02920  -0.03317 0.02105  31  ASP A OD2   
228  N  N     . THR A 39  ? 0.34732 0.30834 0.31779 0.01676  -0.02197 0.00603  32  THR A N     
229  C  CA    . THR A 39  ? 0.34862 0.31520 0.31763 0.01339  -0.02022 0.00508  32  THR A CA    
230  C  C     . THR A 39  ? 0.34246 0.31826 0.32077 0.01227  -0.01765 0.00117  32  THR A C     
231  O  O     . THR A 39  ? 0.28679 0.26685 0.27263 0.01495  -0.01881 -0.00070 32  THR A O     
232  C  CB    . THR A 39  ? 0.35980 0.32798 0.32444 0.01554  -0.02456 0.00657  32  THR A CB    
233  O  OG1   . THR A 39  ? 0.50504 0.46468 0.46181 0.01730  -0.02753 0.01086  32  THR A OG1   
234  C  CG2   . THR A 39  ? 0.31566 0.28468 0.27336 0.01186  -0.02285 0.00543  32  THR A CG2   
235  N  N     . VAL A 40  ? 0.32656 0.30470 0.30384 0.00871  -0.01348 0.00031  33  VAL A N     
236  C  CA    . VAL A 40  ? 0.27128 0.25756 0.25606 0.00818  -0.01087 -0.00297 33  VAL A CA    
237  C  C     . VAL A 40  ? 0.28145 0.26837 0.25995 0.00841  -0.01132 -0.00424 33  VAL A C     
238  O  O     . VAL A 40  ? 0.32382 0.30461 0.29111 0.00703  -0.01035 -0.00262 33  VAL A O     
239  C  CB    . VAL A 40  ? 0.31252 0.30096 0.30167 0.00478  -0.00529 -0.00245 33  VAL A CB    
240  C  CG1   . VAL A 40  ? 0.30709 0.30387 0.30521 0.00523  -0.00294 -0.00541 33  VAL A CG1   
241  C  CG2   . VAL A 40  ? 0.29822 0.28347 0.29073 0.00268  -0.00618 -0.00034 33  VAL A CG2   
242  N  N     . TRP A 41  ? 0.27341 0.26625 0.25749 0.00969  -0.01304 -0.00700 34  TRP A N     
243  C  CA    . TRP A 41  ? 0.25926 0.25128 0.23677 0.00895  -0.01431 -0.00861 34  TRP A CA    
244  C  C     . TRP A 41  ? 0.30225 0.29715 0.28319 0.00833  -0.00942 -0.01177 34  TRP A C     
245  O  O     . TRP A 41  ? 0.24359 0.24467 0.23575 0.00915  -0.00788 -0.01288 34  TRP A O     
246  C  CB    . TRP A 41  ? 0.25927 0.25533 0.24032 0.01039  -0.02124 -0.00829 34  TRP A CB    
247  C  CG    . TRP A 41  ? 0.29553 0.28822 0.27164 0.01146  -0.02620 -0.00444 34  TRP A CG    
248  C  CD1   . TRP A 41  ? 0.27683 0.26922 0.25714 0.01439  -0.02720 -0.00180 34  TRP A CD1   
249  C  CD2   . TRP A 41  ? 0.29032 0.27785 0.25494 0.00974  -0.03100 -0.00251 34  TRP A CD2   
250  N  NE1   . TRP A 41  ? 0.29107 0.27946 0.26467 0.01522  -0.03208 0.00205  34  TRP A NE1   
251  C  CE2   . TRP A 41  ? 0.40845 0.39437 0.37262 0.01206  -0.03497 0.00184  34  TRP A CE2   
252  C  CE3   . TRP A 41  ? 0.30586 0.28825 0.25882 0.00640  -0.03268 -0.00397 34  TRP A CE3   
253  C  CZ2   . TRP A 41  ? 0.41129 0.39252 0.36543 0.01101  -0.04113 0.00527  34  TRP A CZ2   
254  C  CZ3   . TRP A 41  ? 0.39548 0.37183 0.33665 0.00472  -0.03908 -0.00102 34  TRP A CZ3   
255  C  CH2   . TRP A 41  ? 0.42570 0.40237 0.36829 0.00696  -0.04350 0.00382  34  TRP A CH2   
256  N  N     . LEU A 42  ? 0.31143 0.30037 0.28122 0.00713  -0.00696 -0.01304 35  LEU A N     
257  C  CA    . LEU A 42  ? 0.29816 0.28730 0.26875 0.00748  -0.00098 -0.01568 35  LEU A CA    
258  C  C     . LEU A 42  ? 0.32887 0.31009 0.28622 0.00638  -0.00318 -0.01814 35  LEU A C     
259  O  O     . LEU A 42  ? 0.33751 0.30883 0.27879 0.00507  -0.00324 -0.01755 35  LEU A O     
260  C  CB    . LEU A 42  ? 0.30766 0.29484 0.27623 0.00761  0.00762  -0.01397 35  LEU A CB    
261  C  CG    . LEU A 42  ? 0.34837 0.33781 0.32149 0.00933  0.01565  -0.01517 35  LEU A CG    
262  C  CD1   . LEU A 42  ? 0.34739 0.34036 0.32618 0.00920  0.02283  -0.01130 35  LEU A CD1   
263  C  CD2   . LEU A 42  ? 0.38141 0.36015 0.33864 0.01025  0.01897  -0.01805 35  LEU A CD2   
264  N  N     . CYS A 43  ? 0.30074 0.28497 0.26341 0.00642  -0.00543 -0.02071 36  CYS A N     
265  C  CA    . CYS A 43  ? 0.29388 0.26926 0.24400 0.00455  -0.00776 -0.02337 36  CYS A CA    
266  C  C     . CYS A 43  ? 0.36891 0.34013 0.31697 0.00652  0.00039  -0.02619 36  CYS A C     
267  O  O     . CYS A 43  ? 0.33585 0.31564 0.29842 0.00856  0.00327  -0.02650 36  CYS A O     
268  C  CB    . CYS A 43  ? 0.27735 0.25866 0.23529 0.00277  -0.01613 -0.02355 36  CYS A CB    
269  S  SG    . CYS A 43  ? 0.33960 0.32789 0.30328 0.00201  -0.02513 -0.01913 36  CYS A SG    
270  N  N     . CYS A 44  ? 0.33108 0.28826 0.26036 0.00631  0.00422  -0.02802 37  CYS A N     
271  C  CA    . CYS A 44  ? 0.34123 0.29385 0.26858 0.00968  0.01359  -0.03011 37  CYS A CA    
272  C  C     . CYS A 44  ? 0.41844 0.35416 0.32591 0.00843  0.01285  -0.03400 37  CYS A C     
273  O  O     . CYS A 44  ? 0.43279 0.35742 0.32309 0.00448  0.00636  -0.03478 37  CYS A O     
274  C  CB    . CYS A 44  ? 0.41645 0.36796 0.34142 0.01280  0.02407  -0.02785 37  CYS A CB    
275  S  SG    . CYS A 44  ? 0.52297 0.45684 0.42038 0.01131  0.02585  -0.02773 37  CYS A SG    
276  N  N     . GLU A 45  ? 0.39548 0.32853 0.30508 0.01173  0.01915  -0.03617 38  GLU A N     
277  C  CA    . GLU A 45  ? 0.37776 0.29161 0.26678 0.01189  0.02136  -0.04014 38  GLU A CA    
278  C  C     . GLU A 45  ? 0.39184 0.30094 0.27858 0.01881  0.03541  -0.04030 38  GLU A C     
279  O  O     . GLU A 45  ? 0.38881 0.31261 0.29651 0.02276  0.04068  -0.03789 38  GLU A O     
280  C  CB    . GLU A 45  ? 0.44816 0.36221 0.34261 0.00966  0.01510  -0.04241 38  GLU A CB    
281  C  CG    . GLU A 45  ? 0.49646 0.41207 0.39015 0.00263  0.00173  -0.04214 38  GLU A CG    
282  C  CD    . GLU A 45  ? 0.55719 0.47242 0.45613 0.00030  -0.00295 -0.04385 38  GLU A CD    
283  O  OE1   . GLU A 45  ? 0.59867 0.49555 0.47856 -0.00236 -0.00470 -0.04701 38  GLU A OE1   
284  O  OE2   . GLU A 45  ? 0.61481 0.54663 0.53548 0.00099  -0.00472 -0.04197 38  GLU A OE2   
285  N  N     . VAL A 46  ? 0.38477 0.27286 0.24574 0.02034  0.04132  -0.04281 39  VAL A N     
286  C  CA    . VAL A 46  ? 0.43347 0.31356 0.28901 0.02799  0.05584  -0.04317 39  VAL A CA    
287  C  C     . VAL A 46  ? 0.48707 0.34784 0.32607 0.02881  0.05593  -0.04807 39  VAL A C     
288  O  O     . VAL A 46  ? 0.47355 0.31438 0.28734 0.02391  0.04947  -0.05172 39  VAL A O     
289  C  CB    . VAL A 46  ? 0.45865 0.32699 0.29489 0.03045  0.06515  -0.04206 39  VAL A CB    
290  C  CG1   . VAL A 46  ? 0.45526 0.31655 0.28784 0.03954  0.08161  -0.04170 39  VAL A CG1   
291  C  CG2   . VAL A 46  ? 0.40735 0.29390 0.25979 0.02883  0.06436  -0.03689 39  VAL A CG2   
292  N  N     . LYS A 47  ? 0.44730 0.31294 0.29969 0.03468  0.06270  -0.04781 40  LYS A N     
293  C  CA    . LYS A 47  ? 0.48120 0.32879 0.32005 0.03593  0.06298  -0.05211 40  LYS A CA    
294  C  C     . LYS A 47  ? 0.50475 0.34409 0.34006 0.04646  0.07922  -0.05172 40  LYS A C     
295  O  O     . LYS A 47  ? 0.45418 0.30762 0.30472 0.05241  0.08929  -0.04713 40  LYS A O     
296  C  CB    . LYS A 47  ? 0.44782 0.30906 0.30749 0.03257  0.05353  -0.05189 40  LYS A CB    
297  C  CG    . LYS A 47  ? 0.54225 0.40506 0.39948 0.02256  0.03807  -0.05294 40  LYS A CG    
298  C  CD    . LYS A 47  ? 0.71249 0.59235 0.59316 0.01976  0.03021  -0.05153 40  LYS A CD    
299  C  CE    . LYS A 47  ? 0.70587 0.57816 0.57740 0.01081  0.01713  -0.05346 40  LYS A CE    
300  N  NZ    . LYS A 47  ? 0.76013 0.65205 0.65576 0.00771  0.00961  -0.05099 40  LYS A NZ    
301  N  N     . THR A 48  ? 0.52360 0.33919 0.33829 0.04874  0.08185  -0.05616 41  THR A N     
302  C  CA    . THR A 48  ? 0.56968 0.37674 0.38245 0.05984  0.09706  -0.05573 41  THR A CA    
303  C  C     . THR A 48  ? 0.60782 0.43622 0.45252 0.06337  0.09676  -0.05226 41  THR A C     
304  O  O     . THR A 48  ? 0.50867 0.35635 0.37403 0.05712  0.08541  -0.05071 41  THR A O     
305  C  CB    . THR A 48  ? 0.64608 0.41729 0.42340 0.06089  0.09920  -0.06201 41  THR A CB    
306  O  OG1   . THR A 48  ? 0.56190 0.32947 0.33973 0.05323  0.08548  -0.06494 41  THR A OG1   
307  C  CG2   . THR A 48  ? 0.59164 0.34119 0.33614 0.05617  0.09755  -0.06477 41  THR A CG2   
308  N  N     . LYS A 49  ? 0.62252 0.44611 0.47008 0.07387  0.10946  -0.05088 42  LYS A N     
309  C  CA    . LYS A 49  ? 0.72272 0.56267 0.59700 0.07723  0.10831  -0.04772 42  LYS A CA    
310  C  C     . LYS A 49  ? 0.76895 0.59964 0.63734 0.07029  0.09567  -0.05194 42  LYS A C     
311  O  O     . LYS A 49  ? 0.75166 0.60075 0.64374 0.06826  0.08886  -0.04935 42  LYS A O     
312  C  CB    . LYS A 49  ? 0.81531 0.65145 0.69347 0.08963  0.12320  -0.04450 42  LYS A CB    
313  C  CG    . LYS A 49  ? 0.93347 0.79901 0.84379 0.09526  0.13051  -0.03603 42  LYS A CG    
314  C  CD    . LYS A 49  ? 0.92755 0.79918 0.85279 0.10383  0.13778  -0.03040 42  LYS A CD    
315  C  CE    . LYS A 49  ? 0.92755 0.83116 0.88816 0.10708  0.14131  -0.02129 42  LYS A CE    
316  N  NZ    . LYS A 49  ? 0.92457 0.83610 0.90179 0.11495  0.14697  -0.01498 42  LYS A NZ    
317  N  N     . ASP A 50  ? 0.84381 0.64583 0.68046 0.06610  0.09219  -0.05802 43  ASP A N     
318  C  CA    . ASP A 50  ? 0.96682 0.76050 0.79752 0.05735  0.07884  -0.06143 43  ASP A CA    
319  C  C     . ASP A 50  ? 0.96715 0.77548 0.80500 0.04578  0.06448  -0.06106 43  ASP A C     
320  O  O     . ASP A 50  ? 0.98130 0.78016 0.80088 0.04105  0.06155  -0.06302 43  ASP A O     
321  C  CB    . ASP A 50  ? 0.99334 0.74942 0.78666 0.05639  0.07974  -0.06762 43  ASP A CB    
322  C  CG    . ASP A 50  ? 1.16573 0.91161 0.95695 0.05224  0.07184  -0.06970 43  ASP A CG    
323  O  OD1   . ASP A 50  ? 1.22281 0.98120 1.02523 0.04200  0.05798  -0.06908 43  ASP A OD1   
324  O  OD2   . ASP A 50  ? 1.23810 0.96802 1.02030 0.05835  0.07850  -0.07019 43  ASP A OD2   
325  N  N     . PRO A 51  ? 1.22192 1.05230 1.08488 0.04143  0.05565  -0.05833 44  PRO A N     
326  C  CA    . PRO A 51  ? 1.26535 1.11358 1.13948 0.03301  0.04476  -0.05669 44  PRO A CA    
327  C  C     . PRO A 51  ? 1.34422 1.18212 1.20501 0.02225  0.03145  -0.05939 44  PRO A C     
328  O  O     . PRO A 51  ? 1.20860 1.05470 1.07067 0.01576  0.02338  -0.05844 44  PRO A O     
329  C  CB    . PRO A 51  ? 1.18803 1.06328 1.09432 0.03452  0.04299  -0.05223 44  PRO A CB    
330  C  CG    . PRO A 51  ? 1.15593 1.02841 1.06847 0.04386  0.05295  -0.05102 44  PRO A CG    
331  C  CD    . PRO A 51  ? 1.14557 0.98760 1.02966 0.04543  0.05673  -0.05572 44  PRO A CD    
332  N  N     . SER A 52  ? 1.28360 1.10380 1.13234 0.02014  0.02882  -0.06213 45  SER A N     
333  C  CA    . SER A 52  ? 1.25169 1.06754 1.09523 0.00897  0.01503  -0.06303 45  SER A CA    
334  C  C     . SER A 52  ? 1.29453 1.09613 1.11495 0.00162  0.00808  -0.06514 45  SER A C     
335  O  O     . SER A 52  ? 1.28285 1.09582 1.11037 -0.00687 -0.00343 -0.06304 45  SER A O     
336  C  CB    . SER A 52  ? 1.25925 1.05619 1.09241 0.00794  0.01416  -0.06537 45  SER A CB    
337  O  OG    . SER A 52  ? 1.18842 1.00373 1.04677 0.00920  0.01313  -0.06213 45  SER A OG    
338  N  N     . GLY A 53  ? 1.28291 1.05936 1.07522 0.00510  0.01509  -0.06885 46  GLY A N     
339  C  CA    . GLY A 53  ? 1.21913 0.97799 0.98500 -0.00186 0.00845  -0.07106 46  GLY A CA    
340  C  C     . GLY A 53  ? 1.12683 0.90601 0.90450 -0.00407 0.00453  -0.06761 46  GLY A C     
341  O  O     . GLY A 53  ? 1.12288 0.92784 0.92715 0.00084  0.00892  -0.06397 46  GLY A O     
342  N  N     . PRO A 54  ? 0.96625 0.73275 0.72308 -0.01184 -0.00445 -0.06851 47  PRO A N     
343  C  CA    . PRO A 54  ? 0.85646 0.64028 0.62272 -0.01398 -0.00883 -0.06492 47  PRO A CA    
344  C  C     . PRO A 54  ? 0.73355 0.52102 0.50021 -0.00430 0.00527  -0.06438 47  PRO A C     
345  O  O     . PRO A 54  ? 0.69186 0.46144 0.44181 0.00293  0.01767  -0.06731 47  PRO A O     
346  C  CB    . PRO A 54  ? 0.95984 0.72246 0.69718 -0.02382 -0.02068 -0.06640 47  PRO A CB    
347  C  CG    . PRO A 54  ? 0.94476 0.67283 0.64940 -0.02300 -0.01594 -0.07211 47  PRO A CG    
348  C  CD    . PRO A 54  ? 0.94888 0.68238 0.67029 -0.01899 -0.01113 -0.07273 47  PRO A CD    
349  N  N     . PRO A 55  ? 0.69332 0.50339 0.47895 -0.00366 0.00434  -0.06024 48  PRO A N     
350  C  CA    . PRO A 55  ? 0.61249 0.42794 0.40111 0.00463  0.01743  -0.05878 48  PRO A CA    
351  C  C     . PRO A 55  ? 0.55042 0.34032 0.30493 0.00521  0.02224  -0.06121 48  PRO A C     
352  O  O     . PRO A 55  ? 0.56995 0.34138 0.29994 -0.00222 0.01256  -0.06324 48  PRO A O     
353  C  CB    . PRO A 55  ? 0.54899 0.39102 0.36216 0.00268  0.01190  -0.05392 48  PRO A CB    
354  C  CG    . PRO A 55  ? 0.63835 0.47947 0.44724 -0.00698 -0.00398 -0.05337 48  PRO A CG    
355  C  CD    . PRO A 55  ? 0.68897 0.51908 0.49249 -0.01051 -0.00855 -0.05631 48  PRO A CD    
356  N  N     . LEU A 56  ? 0.52709 0.31598 0.27999 0.01405  0.03751  -0.06046 49  LEU A N     
357  C  CA    . LEU A 56  ? 0.53367 0.30006 0.25499 0.01554  0.04406  -0.06194 49  LEU A CA    
358  C  C     . LEU A 56  ? 0.53350 0.30787 0.25403 0.00997  0.03607  -0.05872 49  LEU A C     
359  O  O     . LEU A 56  ? 0.57153 0.32452 0.26161 0.00596  0.03250  -0.06034 49  LEU A O     
360  C  CB    . LEU A 56  ? 0.58005 0.34613 0.30327 0.02696  0.06366  -0.06073 49  LEU A CB    
361  C  CG    . LEU A 56  ? 0.58609 0.34261 0.30876 0.03460  0.07383  -0.06325 49  LEU A CG    
362  C  CD1   . LEU A 56  ? 0.65882 0.42233 0.39120 0.04622  0.09291  -0.05987 49  LEU A CD1   
363  C  CD2   . LEU A 56  ? 0.57633 0.29625 0.26005 0.03244  0.07224  -0.06922 49  LEU A CD2   
364  N  N     . ASP A 57  ? 0.52545 0.32874 0.27756 0.00957  0.03272  -0.05411 50  ASP A N     
365  C  CA    . ASP A 57  ? 0.51344 0.32580 0.26789 0.00495  0.02496  -0.05049 50  ASP A CA    
366  C  C     . ASP A 57  ? 0.45369 0.29573 0.24396 0.00374  0.01842  -0.04672 50  ASP A C     
367  O  O     . ASP A 57  ? 0.47659 0.33239 0.28905 0.00728  0.02219  -0.04655 50  ASP A O     
368  C  CB    . ASP A 57  ? 0.51719 0.32554 0.26161 0.00976  0.03692  -0.04820 50  ASP A CB    
369  C  CG    . ASP A 57  ? 0.58252 0.38215 0.30784 0.00402  0.02868  -0.04649 50  ASP A CG    
370  O  OD1   . ASP A 57  ? 0.59138 0.39609 0.32035 -0.00311 0.01328  -0.04547 50  ASP A OD1   
371  O  OD2   . ASP A 57  ? 0.61337 0.40048 0.31931 0.00687  0.03796  -0.04570 50  ASP A OD2   
372  N  N     . ALA A 58  ? 0.45234 0.30271 0.24659 -0.00108 0.00846  -0.04355 51  ALA A N     
373  C  CA    . ALA A 58  ? 0.43037 0.30623 0.25520 -0.00175 0.00268  -0.03986 51  ALA A CA    
374  C  C     . ALA A 58  ? 0.42206 0.30251 0.24573 -0.00347 -0.00121 -0.03581 51  ALA A C     
375  O  O     . ALA A 58  ? 0.44105 0.30605 0.24115 -0.00697 -0.00570 -0.03581 51  ALA A O     
376  C  CB    . ALA A 58  ? 0.48512 0.36703 0.31968 -0.00697 -0.00969 -0.04032 51  ALA A CB    
377  N  N     . LYS A 59  ? 0.40727 0.30726 0.25477 -0.00111 0.00031  -0.03229 52  LYS A N     
378  C  CA    . LYS A 59  ? 0.41145 0.31510 0.25849 -0.00188 -0.00191 -0.02819 52  LYS A CA    
379  C  C     . LYS A 59  ? 0.42750 0.35183 0.30143 -0.00137 -0.00663 -0.02499 52  LYS A C     
380  O  O     . LYS A 59  ? 0.42039 0.35658 0.31339 0.00080  -0.00423 -0.02576 52  LYS A O     
381  C  CB    . LYS A 59  ? 0.47751 0.37598 0.31681 0.00193  0.01089  -0.02695 52  LYS A CB    
382  C  CG    . LYS A 59  ? 0.61419 0.48924 0.42090 0.00117  0.01453  -0.02875 52  LYS A CG    
383  C  CD    . LYS A 59  ? 0.66110 0.53202 0.45692 0.00009  0.01482  -0.02471 52  LYS A CD    
384  C  CE    . LYS A 59  ? 0.74591 0.59165 0.50636 -0.00066 0.01874  -0.02639 52  LYS A CE    
385  N  NZ    . LYS A 59  ? 0.75698 0.58629 0.49634 -0.00561 0.00782  -0.03005 52  LYS A NZ    
386  N  N     . ILE A 60  ? 0.40190 0.32895 0.27568 -0.00306 -0.01320 -0.02126 53  ILE A N     
387  C  CA    . ILE A 60  ? 0.37721 0.32039 0.27271 -0.00161 -0.01621 -0.01796 53  ILE A CA    
388  C  C     . ILE A 60  ? 0.39757 0.33916 0.28982 -0.00031 -0.01129 -0.01467 53  ILE A C     
389  O  O     . ILE A 60  ? 0.42375 0.35440 0.29814 -0.00205 -0.01326 -0.01292 53  ILE A O     
390  C  CB    . ILE A 60  ? 0.37624 0.32519 0.27738 -0.00401 -0.02866 -0.01556 53  ILE A CB    
391  C  CG1   . ILE A 60  ? 0.44294 0.39546 0.35035 -0.00596 -0.03338 -0.01797 53  ILE A CG1   
392  C  CG2   . ILE A 60  ? 0.41905 0.38108 0.33854 -0.00126 -0.03033 -0.01184 53  ILE A CG2   
393  C  CD1   . ILE A 60  ? 0.39756 0.35304 0.30595 -0.00972 -0.04596 -0.01491 53  ILE A CD1   
394  N  N     . PHE A 61  ? 0.34994 0.30133 0.25820 0.00216  -0.00519 -0.01357 54  PHE A N     
395  C  CA    . PHE A 61  ? 0.36276 0.31380 0.27082 0.00261  -0.00060 -0.00995 54  PHE A CA    
396  C  C     . PHE A 61  ? 0.41530 0.37622 0.33950 0.00333  -0.00546 -0.00740 54  PHE A C     
397  O  O     . PHE A 61  ? 0.30852 0.27892 0.24797 0.00454  -0.00750 -0.00883 54  PHE A O     
398  C  CB    . PHE A 61  ? 0.38613 0.33901 0.29847 0.00417  0.01116  -0.00994 54  PHE A CB    
399  C  CG    . PHE A 61  ? 0.44729 0.38823 0.34154 0.00485  0.01864  -0.01175 54  PHE A CG    
400  C  CD1   . PHE A 61  ? 0.42245 0.35122 0.29716 0.00394  0.02206  -0.00960 54  PHE A CD1   
401  C  CD2   . PHE A 61  ? 0.44965 0.38960 0.34444 0.00674  0.02254  -0.01558 54  PHE A CD2   
402  C  CE1   . PHE A 61  ? 0.45035 0.36559 0.30535 0.00521  0.03001  -0.01147 54  PHE A CE1   
403  C  CE2   . PHE A 61  ? 0.39281 0.31914 0.26871 0.00824  0.03025  -0.01748 54  PHE A CE2   
404  C  CZ    . PHE A 61  ? 0.41425 0.32786 0.26964 0.00761  0.03427  -0.01557 54  PHE A CZ    
405  N  N     . GLN A 62  ? 0.36994 0.32697 0.28918 0.00281  -0.00683 -0.00357 55  GLN A N     
406  C  CA    . GLN A 62  ? 0.38153 0.34444 0.31309 0.00399  -0.01040 -0.00112 55  GLN A CA    
407  C  C     . GLN A 62  ? 0.38299 0.34151 0.31145 0.00279  -0.00550 0.00242  55  GLN A C     
408  O  O     . GLN A 62  ? 0.43584 0.38629 0.35057 0.00125  -0.00131 0.00403  55  GLN A O     
409  C  CB    . GLN A 62  ? 0.39778 0.36014 0.32760 0.00503  -0.02003 0.00090  55  GLN A CB    
410  C  CG    . GLN A 62  ? 0.53457 0.48620 0.44633 0.00346  -0.02325 0.00392  55  GLN A CG    
411  C  CD    . GLN A 62  ? 0.50556 0.45812 0.41929 0.00528  -0.03234 0.00787  55  GLN A CD    
412  O  OE1   . GLN A 62  ? 0.51338 0.46840 0.43599 0.00793  -0.03264 0.01013  55  GLN A OE1   
413  N  NE2   . GLN A 62  ? 0.62364 0.57346 0.52860 0.00390  -0.03998 0.00910  55  GLN A NE2   
414  N  N     . GLY A 63  ? 0.34823 0.31085 0.28826 0.00319  -0.00601 0.00384  56  GLY A N     
415  C  CA    . GLY A 63  ? 0.42508 0.38278 0.36250 0.00107  -0.00268 0.00776  56  GLY A CA    
416  C  C     . GLY A 63  ? 0.41416 0.37232 0.36029 0.00168  -0.00639 0.00905  56  GLY A C     
417  O  O     . GLY A 63  ? 0.35719 0.32182 0.31465 0.00314  -0.00799 0.00649  56  GLY A O     
418  N  N     . LYS A 64  ? 0.39465 0.34418 0.33383 0.00070  -0.00772 0.01298  57  LYS A N     
419  C  CA    . LYS A 64  ? 0.41498 0.36115 0.35924 0.00139  -0.01091 0.01410  57  LYS A CA    
420  C  C     . LYS A 64  ? 0.41948 0.36960 0.37389 -0.00235 -0.00739 0.01368  57  LYS A C     
421  O  O     . LYS A 64  ? 0.39046 0.34318 0.34631 -0.00641 -0.00190 0.01552  57  LYS A O     
422  C  CB    . LYS A 64  ? 0.48155 0.41551 0.41454 0.00080  -0.01278 0.01877  57  LYS A CB    
423  C  CG    . LYS A 64  ? 0.52244 0.45238 0.44615 0.00467  -0.01797 0.02028  57  LYS A CG    
424  C  CD    . LYS A 64  ? 0.56694 0.50030 0.49812 0.01044  -0.02351 0.01896  57  LYS A CD    
425  C  CE    . LYS A 64  ? 0.67197 0.60557 0.59793 0.01391  -0.02945 0.02113  57  LYS A CE    
426  N  NZ    . LYS A 64  ? 0.66318 0.60715 0.59372 0.01392  -0.03092 0.01796  57  LYS A NZ    
427  N  N     . VAL A 65  ? 0.36783 0.31831 0.32923 -0.00099 -0.01055 0.01178  58  VAL A N     
428  C  CA    . VAL A 65  ? 0.39312 0.34662 0.36336 -0.00533 -0.00897 0.01172  58  VAL A CA    
429  C  C     . VAL A 65  ? 0.42743 0.37329 0.39395 -0.01115 -0.00775 0.01648  58  VAL A C     
430  O  O     . VAL A 65  ? 0.48455 0.43623 0.45868 -0.01645 -0.00442 0.01865  58  VAL A O     
431  C  CB    . VAL A 65  ? 0.54344 0.49540 0.51788 -0.00291 -0.01301 0.00873  58  VAL A CB    
432  C  CG1   . VAL A 65  ? 0.53646 0.49139 0.51908 -0.00830 -0.01266 0.00893  58  VAL A CG1   
433  C  CG2   . VAL A 65  ? 0.46586 0.42638 0.44506 0.00231  -0.01366 0.00486  58  VAL A CG2   
434  N  N     . TYR A 66  ? 0.42073 0.35388 0.37639 -0.01033 -0.01047 0.01885  59  TYR A N     
435  C  CA    . TYR A 66  ? 0.50753 0.43085 0.45771 -0.01607 -0.00998 0.02377  59  TYR A CA    
436  C  C     . TYR A 66  ? 0.46682 0.38402 0.40520 -0.01511 -0.00836 0.02717  59  TYR A C     
437  O  O     . TYR A 66  ? 0.45188 0.36720 0.38394 -0.00926 -0.01083 0.02585  59  TYR A O     
438  C  CB    . TYR A 66  ? 0.42735 0.33658 0.37252 -0.01620 -0.01524 0.02367  59  TYR A CB    
439  C  CG    . TYR A 66  ? 0.52720 0.43999 0.48110 -0.01842 -0.01723 0.02072  59  TYR A CG    
440  C  CD1   . TYR A 66  ? 0.57622 0.49572 0.53952 -0.02636 -0.01602 0.02300  59  TYR A CD1   
441  C  CD2   . TYR A 66  ? 0.45211 0.36331 0.40587 -0.01239 -0.02002 0.01616  59  TYR A CD2   
442  C  CE1   . TYR A 66  ? 0.56336 0.48598 0.53408 -0.02882 -0.01899 0.02077  59  TYR A CE1   
443  C  CE2   . TYR A 66  ? 0.45979 0.37317 0.41947 -0.01446 -0.02192 0.01346  59  TYR A CE2   
444  C  CZ    . TYR A 66  ? 0.57638 0.49499 0.54396 -0.02289 -0.02200 0.01570  59  TYR A CZ    
445  O  OH    . TYR A 66  ? 0.48369 0.40407 0.45645 -0.02535 -0.02505 0.01350  59  TYR A OH    
446  N  N     . PRO A 67  ? 0.56420 0.47823 0.49939 -0.02106 -0.00451 0.03224  60  PRO A N     
447  C  CA    . PRO A 67  ? 0.55171 0.46678 0.49450 -0.02909 -0.00271 0.03584  60  PRO A CA    
448  C  C     . PRO A 67  ? 0.62481 0.55594 0.58108 -0.03279 0.00397  0.03726  60  PRO A C     
449  O  O     . PRO A 67  ? 0.71679 0.65213 0.68387 -0.03904 0.00355  0.03981  60  PRO A O     
450  C  CB    . PRO A 67  ? 0.68526 0.58731 0.61614 -0.03283 -0.00196 0.04176  60  PRO A CB    
451  C  CG    . PRO A 67  ? 0.64872 0.55145 0.56969 -0.02826 0.00146  0.04195  60  PRO A CG    
452  C  CD    . PRO A 67  ? 0.62273 0.53155 0.54550 -0.02060 -0.00172 0.03566  60  PRO A CD    
453  N  N     . LYS A 68  ? 0.59979 0.53897 0.55527 -0.02913 0.00973  0.03603  61  LYS A N     
454  C  CA    . LYS A 68  ? 0.58707 0.53924 0.55324 -0.03170 0.01805  0.03869  61  LYS A CA    
455  C  C     . LYS A 68  ? 0.60196 0.56531 0.57524 -0.02650 0.02011  0.03343  61  LYS A C     
456  O  O     . LYS A 68  ? 0.51292 0.47325 0.47645 -0.02103 0.01947  0.02929  61  LYS A O     
457  C  CB    . LYS A 68  ? 0.68269 0.63116 0.63835 -0.03262 0.02578  0.04338  61  LYS A CB    
458  C  CG    . LYS A 68  ? 0.80456 0.74639 0.75885 -0.03990 0.02641  0.05063  61  LYS A CG    
459  C  CD    . LYS A 68  ? 0.74430 0.69606 0.71790 -0.04684 0.02578  0.05425  61  LYS A CD    
460  C  CE    . LYS A 68  ? 0.91178 0.85207 0.88215 -0.05463 0.02092  0.05951  61  LYS A CE    
461  N  NZ    . LYS A 68  ? 0.99608 0.94607 0.98087 -0.06338 0.02588  0.06793  61  LYS A NZ    
462  N  N     . ALA A 69  ? 0.52798 0.50398 0.51832 -0.02869 0.02212  0.03420  62  ALA A N     
463  C  CA    . ALA A 69  ? 0.49182 0.47835 0.48998 -0.02403 0.02469  0.02996  62  ALA A CA    
464  C  C     . ALA A 69  ? 0.51077 0.49883 0.50198 -0.02018 0.03393  0.02994  62  ALA A C     
465  O  O     . ALA A 69  ? 0.51149 0.50283 0.50235 -0.01527 0.03525  0.02521  62  ALA A O     
466  C  CB    . ALA A 69  ? 0.55442 0.55417 0.57271 -0.02751 0.02508  0.03240  62  ALA A CB    
467  N  N     . LYS A 70  ? 0.58208 0.56626 0.56618 -0.02237 0.04058  0.03515  63  LYS A N     
468  C  CA    . LYS A 70  ? 0.56342 0.54655 0.53794 -0.01845 0.05044  0.03515  63  LYS A CA    
469  C  C     . LYS A 70  ? 0.52393 0.49551 0.47878 -0.01383 0.04664  0.02922  63  LYS A C     
470  O  O     . LYS A 70  ? 0.48501 0.45399 0.43022 -0.01003 0.05297  0.02710  63  LYS A O     
471  C  CB    . LYS A 70  ? 0.55167 0.53183 0.52103 -0.02190 0.05875  0.04250  63  LYS A CB    
472  C  CG    . LYS A 70  ? 0.63665 0.60074 0.58497 -0.02294 0.05511  0.04309  63  LYS A CG    
473  C  CD    . LYS A 70  ? 0.83896 0.80025 0.78443 -0.02791 0.06202  0.05137  63  LYS A CD    
474  C  CE    . LYS A 70  ? 0.85636 0.82342 0.81869 -0.03520 0.05758  0.05652  63  LYS A CE    
475  N  NZ    . LYS A 70  ? 0.92598 0.88107 0.87707 -0.04038 0.05650  0.06217  63  LYS A NZ    
476  N  N     . TYR A 71  ? 0.50368 0.46793 0.45232 -0.01403 0.03637  0.02685  64  TYR A N     
477  C  CA    . TYR A 71  ? 0.45854 0.41474 0.39259 -0.01016 0.03096  0.02206  64  TYR A CA    
478  C  C     . TYR A 71  ? 0.43435 0.39659 0.37786 -0.00745 0.02402  0.01661  64  TYR A C     
479  O  O     . TYR A 71  ? 0.45867 0.41616 0.39372 -0.00494 0.01775  0.01345  64  TYR A O     
480  C  CB    . TYR A 71  ? 0.46592 0.40992 0.38573 -0.01119 0.02496  0.02434  64  TYR A CB    
481  C  CG    . TYR A 71  ? 0.68694 0.62311 0.59419 -0.01382 0.03186  0.02979  64  TYR A CG    
482  C  CD1   . TYR A 71  ? 0.70140 0.63688 0.61378 -0.01849 0.03363  0.03557  64  TYR A CD1   
483  C  CD2   . TYR A 71  ? 0.80756 0.73610 0.69685 -0.01203 0.03703  0.02931  64  TYR A CD2   
484  C  CE1   . TYR A 71  ? 0.81490 0.74349 0.71603 -0.02117 0.04064  0.04123  64  TYR A CE1   
485  C  CE2   . TYR A 71  ? 0.85991 0.78042 0.73612 -0.01417 0.04439  0.03453  64  TYR A CE2   
486  C  CZ    . TYR A 71  ? 0.86277 0.78420 0.74587 -0.01866 0.04648  0.04072  64  TYR A CZ    
487  O  OH    . TYR A 71  ? 0.93849 0.85223 0.80889 -0.02105 0.05434  0.04655  64  TYR A OH    
488  N  N     . HIS A 72  ? 0.39252 0.36544 0.35354 -0.00814 0.02479  0.01605  65  HIS A N     
489  C  CA    . HIS A 72  ? 0.32944 0.30800 0.29831 -0.00534 0.01992  0.01102  65  HIS A CA    
490  C  C     . HIS A 72  ? 0.39317 0.37196 0.35607 -0.00197 0.02371  0.00735  65  HIS A C     
491  O  O     . HIS A 72  ? 0.34352 0.32081 0.30091 -0.00156 0.03212  0.00882  65  HIS A O     
492  C  CB    . HIS A 72  ? 0.34165 0.33033 0.32876 -0.00729 0.01991  0.01181  65  HIS A CB    
493  C  CG    . HIS A 72  ? 0.40875 0.39403 0.39906 -0.01062 0.01390  0.01389  65  HIS A CG    
494  N  ND1   . HIS A 72  ? 0.38611 0.37726 0.38968 -0.01376 0.01185  0.01505  65  HIS A ND1   
495  C  CD2   . HIS A 72  ? 0.44186 0.41666 0.42227 -0.01126 0.00927  0.01513  65  HIS A CD2   
496  C  CE1   . HIS A 72  ? 0.46263 0.44558 0.46280 -0.01648 0.00632  0.01640  65  HIS A CE1   
497  N  NE2   . HIS A 72  ? 0.44281 0.41585 0.42940 -0.01457 0.00509  0.01652  65  HIS A NE2   
498  N  N     . PRO A 73  ? 0.33774 0.31705 0.30033 0.00046  0.01795  0.00283  66  PRO A N     
499  C  CA    . PRO A 73  ? 0.34786 0.32389 0.30127 0.00275  0.02025  -0.00072 66  PRO A CA    
500  C  C     . PRO A 73  ? 0.36589 0.34741 0.32636 0.00434  0.02914  -0.00125 66  PRO A C     
501  O  O     . PRO A 73  ? 0.35217 0.32701 0.30063 0.00625  0.03434  -0.00304 66  PRO A O     
502  C  CB    . PRO A 73  ? 0.32591 0.30405 0.28247 0.00404  0.01158  -0.00438 66  PRO A CB    
503  C  CG    . PRO A 73  ? 0.31634 0.30211 0.28841 0.00367  0.00803  -0.00347 66  PRO A CG    
504  C  CD    . PRO A 73  ? 0.33668 0.31888 0.30676 0.00119  0.00965  0.00103  66  PRO A CD    
505  N  N     . GLU A 74  ? 0.38275 0.37523 0.36147 0.00373  0.03090  0.00059  67  GLU A N     
506  C  CA    . GLU A 74  ? 0.32013 0.31957 0.30820 0.00572  0.03961  0.00164  67  GLU A CA    
507  C  C     . GLU A 74  ? 0.38012 0.37579 0.36039 0.00627  0.05015  0.00544  67  GLU A C     
508  O  O     . GLU A 74  ? 0.31453 0.30826 0.29061 0.01007  0.05857  0.00459  67  GLU A O     
509  C  CB    . GLU A 74  ? 0.34609 0.35827 0.35539 0.00379  0.03812  0.00450  67  GLU A CB    
510  C  CG    . GLU A 74  ? 0.28982 0.30503 0.30610 0.00355  0.02897  0.00107  67  GLU A CG    
511  C  CD    . GLU A 74  ? 0.39254 0.40464 0.40788 0.00030  0.02137  0.00202  67  GLU A CD    
512  O  OE1   . GLU A 74  ? 0.31322 0.31670 0.31584 -0.00013 0.01955  0.00219  67  GLU A OE1   
513  O  OE2   . GLU A 74  ? 0.34005 0.35701 0.36611 -0.00157 0.01708  0.00264  67  GLU A OE2   
514  N  N     . MET A 75  ? 0.30126 0.29513 0.27918 0.00280  0.05055  0.00997  68  MET A N     
515  C  CA    . MET A 75  ? 0.37225 0.36225 0.34197 0.00311  0.06123  0.01430  68  MET A CA    
516  C  C     . MET A 75  ? 0.35962 0.33342 0.30316 0.00533  0.06308  0.01106  68  MET A C     
517  O  O     . MET A 75  ? 0.38360 0.35195 0.31698 0.00820  0.07394  0.01216  68  MET A O     
518  C  CB    . MET A 75  ? 0.39862 0.39038 0.37274 -0.00210 0.06038  0.02046  68  MET A CB    
519  C  CG    . MET A 75  ? 0.35407 0.35970 0.35193 -0.00592 0.05757  0.02439  68  MET A CG    
520  S  SD    . MET A 75  ? 0.42580 0.44793 0.44541 -0.00307 0.06653  0.02729  68  MET A SD    
521  C  CE    . MET A 75  ? 0.59542 0.62152 0.61773 -0.00440 0.08002  0.03634  68  MET A CE    
522  N  N     . ARG A 76  ? 0.40607 0.37145 0.33776 0.00405  0.05267  0.00760  69  ARG A N     
523  C  CA    . ARG A 76  ? 0.37748 0.32728 0.28413 0.00528  0.05210  0.00446  69  ARG A CA    
524  C  C     . ARG A 76  ? 0.37577 0.32207 0.27730 0.00913  0.05665  -0.00021 69  ARG A C     
525  O  O     . ARG A 76  ? 0.36986 0.30279 0.25083 0.01108  0.06337  -0.00138 69  ARG A O     
526  C  CB    . ARG A 76  ? 0.35435 0.29919 0.25411 0.00322  0.03879  0.00240  69  ARG A CB    
527  C  CG    . ARG A 76  ? 0.48277 0.42729 0.38373 0.00023  0.03444  0.00704  69  ARG A CG    
528  C  CD    . ARG A 76  ? 0.51160 0.45195 0.40698 -0.00041 0.02197  0.00575  69  ARG A CD    
529  N  NE    . ARG A 76  ? 0.50568 0.44512 0.40329 -0.00223 0.01780  0.01003  69  ARG A NE    
530  C  CZ    . ARG A 76  ? 0.69248 0.62106 0.57381 -0.00342 0.01532  0.01311  69  ARG A CZ    
531  N  NH1   . ARG A 76  ? 0.67461 0.59195 0.53509 -0.00350 0.01675  0.01253  69  ARG A NH1   
532  N  NH2   . ARG A 76  ? 0.58991 0.51717 0.47431 -0.00458 0.01116  0.01691  69  ARG A NH2   
533  N  N     . PHE A 77  ? 0.35068 0.30696 0.26878 0.01033  0.05315  -0.00294 70  PHE A N     
534  C  CA    . PHE A 77  ? 0.32973 0.28261 0.24451 0.01414  0.05771  -0.00701 70  PHE A CA    
535  C  C     . PHE A 77  ? 0.36353 0.31579 0.27748 0.01828  0.07276  -0.00428 70  PHE A C     
536  O  O     . PHE A 77  ? 0.40563 0.34397 0.30053 0.02164  0.07955  -0.00695 70  PHE A O     
537  C  CB    . PHE A 77  ? 0.30395 0.26945 0.23950 0.01477  0.05265  -0.00902 70  PHE A CB    
538  C  CG    . PHE A 77  ? 0.35136 0.31384 0.28551 0.01911  0.05865  -0.01224 70  PHE A CG    
539  C  CD1   . PHE A 77  ? 0.36608 0.31603 0.28412 0.01915  0.05402  -0.01758 70  PHE A CD1   
540  C  CD2   . PHE A 77  ? 0.35469 0.32548 0.30221 0.02314  0.06927  -0.00929 70  PHE A CD2   
541  C  CE1   . PHE A 77  ? 0.42426 0.36834 0.33838 0.02315  0.05969  -0.02065 70  PHE A CE1   
542  C  CE2   . PHE A 77  ? 0.34921 0.31531 0.29394 0.02819  0.07558  -0.01199 70  PHE A CE2   
543  C  CZ    . PHE A 77  ? 0.40600 0.35757 0.33293 0.02821  0.07086  -0.01800 70  PHE A CZ    
544  N  N     . LEU A 78  ? 0.36994 0.33708 0.30485 0.01820  0.07822  0.00138  71  LEU A N     
545  C  CA    . LEU A 78  ? 0.38264 0.35321 0.32214 0.02273  0.09321  0.00544  71  LEU A CA    
546  C  C     . LEU A 78  ? 0.39338 0.34800 0.30766 0.02422  0.10256  0.00654  71  LEU A C     
547  O  O     . LEU A 78  ? 0.43589 0.38269 0.33990 0.03001  0.11474  0.00610  71  LEU A O     
548  C  CB    . LEU A 78  ? 0.36435 0.35447 0.33122 0.02050  0.09556  0.01278  71  LEU A CB    
549  C  CG    . LEU A 78  ? 0.36183 0.36792 0.35415 0.02024  0.08984  0.01288  71  LEU A CG    
550  C  CD1   . LEU A 78  ? 0.39503 0.41882 0.41210 0.01740  0.09280  0.02116  71  LEU A CD1   
551  C  CD2   . LEU A 78  ? 0.41875 0.42356 0.41168 0.02691  0.09562  0.00967  71  LEU A CD2   
552  N  N     . ARG A 79  ? 0.40527 0.35354 0.30794 0.01950  0.09742  0.00813  72  ARG A N     
553  C  CA    . ARG A 79  ? 0.44471 0.37636 0.32101 0.02036  0.10550  0.00943  72  ARG A CA    
554  C  C     . ARG A 79  ? 0.48883 0.39897 0.33558 0.02255  0.10376  0.00243  72  ARG A C     
555  O  O     . ARG A 79  ? 0.50826 0.40440 0.33519 0.02693  0.11570  0.00196  72  ARG A O     
556  C  CB    . ARG A 79  ? 0.50103 0.43074 0.37233 0.01451  0.09893  0.01311  72  ARG A CB    
557  C  CG    . ARG A 79  ? 0.49857 0.44550 0.39441 0.01162  0.10251  0.02084  72  ARG A CG    
558  C  CD    . ARG A 79  ? 0.51105 0.45235 0.39792 0.00632  0.09880  0.02525  72  ARG A CD    
559  N  NE    . ARG A 79  ? 0.55209 0.49050 0.43701 0.00263  0.08285  0.02215  72  ARG A NE    
560  C  CZ    . ARG A 79  ? 0.56617 0.51585 0.47087 -0.00091 0.07451  0.02375  72  ARG A CZ    
561  N  NH1   . ARG A 79  ? 0.47109 0.43584 0.39921 -0.00255 0.07871  0.02835  72  ARG A NH1   
562  N  NH2   . ARG A 79  ? 0.49913 0.44437 0.39967 -0.00279 0.06154  0.02102  72  ARG A NH2   
563  N  N     . TRP A 80  ? 0.43556 0.34221 0.27860 0.01948  0.08923  -0.00276 73  TRP A N     
564  C  CA    . TRP A 80  ? 0.52451 0.41104 0.34067 0.02010  0.08571  -0.00905 73  TRP A CA    
565  C  C     . TRP A 80  ? 0.49345 0.37570 0.30827 0.02628  0.09592  -0.01222 73  TRP A C     
566  O  O     . TRP A 80  ? 0.50790 0.36968 0.29561 0.02940  0.10370  -0.01486 73  TRP A O     
567  C  CB    . TRP A 80  ? 0.50844 0.39662 0.32738 0.01543  0.06818  -0.01273 73  TRP A CB    
568  C  CG    . TRP A 80  ? 0.49136 0.36291 0.28996 0.01547  0.06391  -0.01900 73  TRP A CG    
569  C  CD1   . TRP A 80  ? 0.52294 0.37200 0.28915 0.01312  0.06034  -0.02149 73  TRP A CD1   
570  C  CD2   . TRP A 80  ? 0.46438 0.33895 0.27223 0.01722  0.06211  -0.02325 73  TRP A CD2   
571  N  NE1   . TRP A 80  ? 0.54529 0.38264 0.29979 0.01286  0.05632  -0.02711 73  TRP A NE1   
572  C  CE2   . TRP A 80  ? 0.52214 0.37496 0.30214 0.01551  0.05760  -0.02825 73  TRP A CE2   
573  C  CE3   . TRP A 80  ? 0.46103 0.35346 0.29683 0.01971  0.06351  -0.02306 73  TRP A CE3   
574  C  CZ2   . TRP A 80  ? 0.53282 0.38126 0.31272 0.01606  0.05473  -0.03299 73  TRP A CZ2   
575  C  CZ3   . TRP A 80  ? 0.46487 0.35353 0.30069 0.02077  0.06085  -0.02768 73  TRP A CZ3   
576  C  CH2   . TRP A 80  ? 0.52983 0.39663 0.33814 0.01895  0.05676  -0.03257 73  TRP A CH2   
577  N  N     . PHE A 81  ? 0.42936 0.32947 0.27208 0.02841  0.09632  -0.01177 74  PHE A N     
578  C  CA    . PHE A 81  ? 0.46086 0.35792 0.30486 0.03464  0.10472  -0.01451 74  PHE A CA    
579  C  C     . PHE A 81  ? 0.51415 0.40446 0.34912 0.04150  0.12349  -0.01129 74  PHE A C     
580  O  O     . PHE A 81  ? 0.48006 0.35375 0.29681 0.04712  0.13188  -0.01490 74  PHE A O     
581  C  CB    . PHE A 81  ? 0.41158 0.33134 0.28951 0.03539  0.10162  -0.01294 74  PHE A CB    
582  C  CG    . PHE A 81  ? 0.43772 0.35415 0.31767 0.04085  0.10579  -0.01646 74  PHE A CG    
583  C  CD1   . PHE A 81  ? 0.49017 0.38568 0.34549 0.04086  0.10198  -0.02318 74  PHE A CD1   
584  C  CD2   . PHE A 81  ? 0.43015 0.36379 0.33646 0.04556  0.11279  -0.01260 74  PHE A CD2   
585  C  CE1   . PHE A 81  ? 0.46092 0.35156 0.31709 0.04576  0.10569  -0.02635 74  PHE A CE1   
586  C  CE2   . PHE A 81  ? 0.47051 0.40040 0.37858 0.05110  0.11657  -0.01544 74  PHE A CE2   
587  C  CZ    . PHE A 81  ? 0.44222 0.35002 0.32481 0.05133  0.11328  -0.02250 74  PHE A CZ    
588  N  N     . HIS A 82  ? 0.43276 0.33492 0.27965 0.04125  0.13077  -0.00417 75  HIS A N     
589  C  CA    . HIS A 82  ? 0.52675 0.42543 0.36842 0.04810  0.14992  0.00030  75  HIS A CA    
590  C  C     . HIS A 82  ? 0.58813 0.45703 0.38811 0.04984  0.15589  -0.00340 75  HIS A C     
591  O  O     . HIS A 82  ? 0.56323 0.41897 0.34838 0.05767  0.17075  -0.00414 75  HIS A O     
592  C  CB    . HIS A 82  ? 0.51172 0.42994 0.37552 0.04583  0.15514  0.00950  75  HIS A CB    
593  C  CG    . HIS A 82  ? 0.56524 0.48119 0.42424 0.05232  0.17537  0.01548  75  HIS A CG    
594  N  ND1   . HIS A 82  ? 0.72018 0.61674 0.54884 0.05260  0.18305  0.01609  75  HIS A ND1   
595  C  CD2   . HIS A 82  ? 0.58896 0.51961 0.46963 0.05929  0.19010  0.02161  75  HIS A CD2   
596  C  CE1   . HIS A 82  ? 0.70102 0.60034 0.53262 0.05962  0.20258  0.02227  75  HIS A CE1   
597  N  NE2   . HIS A 82  ? 0.72661 0.64747 0.59110 0.06381  0.20670  0.02593  75  HIS A NE2   
598  N  N     . LYS A 83  ? 0.60421 0.46098 0.38372 0.04292  0.14438  -0.00559 76  LYS A N     
599  C  CA    . LYS A 83  ? 0.58845 0.41497 0.32564 0.04347  0.14782  -0.00924 76  LYS A CA    
600  C  C     . LYS A 83  ? 0.61708 0.42334 0.33278 0.04448  0.14217  -0.01776 76  LYS A C     
601  O  O     . LYS A 83  ? 0.66713 0.44753 0.35035 0.04877  0.15151  -0.02109 76  LYS A O     
602  C  CB    . LYS A 83  ? 0.68572 0.50512 0.40719 0.03561  0.13629  -0.00818 76  LYS A CB    
603  C  CG    . LYS A 83  ? 0.81257 0.65410 0.55997 0.03090  0.13187  -0.00123 76  LYS A CG    
604  C  CD    . LYS A 83  ? 0.92150 0.77896 0.68931 0.03492  0.14867  0.00684  76  LYS A CD    
605  C  CE    . LYS A 83  ? 0.77400 0.65629 0.57454 0.02928  0.14092  0.01269  76  LYS A CE    
606  N  NZ    . LYS A 83  ? 0.68164 0.58817 0.51660 0.03183  0.15082  0.01938  76  LYS A NZ    
607  N  N     . TRP A 84  ? 0.54363 0.35984 0.27552 0.04026  0.12696  -0.02121 77  TRP A N     
608  C  CA    . TRP A 84  ? 0.51979 0.31887 0.23497 0.04015  0.12058  -0.02864 77  TRP A CA    
609  C  C     . TRP A 84  ? 0.61046 0.40184 0.32279 0.04974  0.13664  -0.03021 77  TRP A C     
610  O  O     . TRP A 84  ? 0.61627 0.38132 0.29899 0.05162  0.13878  -0.03526 77  TRP A O     
611  C  CB    . TRP A 84  ? 0.52739 0.34405 0.26759 0.03462  0.10363  -0.03031 77  TRP A CB    
612  C  CG    . TRP A 84  ? 0.59761 0.39824 0.32272 0.03296  0.09552  -0.03715 77  TRP A CG    
613  C  CD1   . TRP A 84  ? 0.65206 0.43555 0.35358 0.02575  0.08134  -0.04116 77  TRP A CD1   
614  C  CD2   . TRP A 84  ? 0.53899 0.33882 0.27163 0.03818  0.10075  -0.04014 77  TRP A CD2   
615  N  NE1   . TRP A 84  ? 0.62942 0.40124 0.32324 0.02548  0.07735  -0.04655 77  TRP A NE1   
616  C  CE2   . TRP A 84  ? 0.59569 0.37642 0.30751 0.03336  0.08942  -0.04625 77  TRP A CE2   
617  C  CE3   . TRP A 84  ? 0.53106 0.34462 0.28654 0.04629  0.11346  -0.03764 77  TRP A CE3   
618  C  CZ2   . TRP A 84  ? 0.62019 0.39367 0.33199 0.03642  0.09093  -0.05031 77  TRP A CZ2   
619  C  CZ3   . TRP A 84  ? 0.56345 0.37021 0.31911 0.05009  0.11503  -0.04154 77  TRP A CZ3   
620  C  CH2   . TRP A 84  ? 0.65927 0.44540 0.39252 0.04517  0.10405  -0.04803 77  TRP A CH2   
621  N  N     . ARG A 85  ? 0.54657 0.36142 0.29160 0.05547  0.14669  -0.02505 78  ARG A N     
622  C  CA    . ARG A 85  ? 0.62128 0.43240 0.36908 0.06531  0.16138  -0.02507 78  ARG A CA    
623  C  C     . ARG A 85  ? 0.63151 0.42565 0.35915 0.06958  0.17237  -0.02280 78  ARG A C     
624  O  O     . ARG A 85  ? 0.63326 0.41401 0.35232 0.07512  0.17782  -0.02450 78  ARG A O     
625  C  CB    . ARG A 85  ? 0.52871 0.37138 0.31863 0.06967  0.16829  -0.01827 78  ARG A CB    
626  C  CG    . ARG A 85  ? 0.55660 0.41683 0.37285 0.06533  0.15338  -0.02003 78  ARG A CG    
627  C  CD    . ARG A 85  ? 0.54956 0.44095 0.40648 0.06743  0.15717  -0.01245 78  ARG A CD    
628  N  NE    . ARG A 85  ? 0.62008 0.51515 0.48880 0.07743  0.17034  -0.01036 78  ARG A NE    
629  C  CZ    . ARG A 85  ? 0.66603 0.58734 0.56991 0.08064  0.17542  -0.00287 78  ARG A CZ    
630  N  NH1   . ARG A 85  ? 0.58329 0.52763 0.51204 0.07420  0.16882  0.00286  78  ARG A NH1   
631  N  NH2   . ARG A 85  ? 0.60640 0.53121 0.52213 0.08830  0.18259  -0.00040 78  ARG A NH2   
632  N  N     . GLN A 86  ? 0.63542 0.42865 0.35431 0.06729  0.17611  -0.01876 79  GLN A N     
633  C  CA    . GLN A 86  ? 0.70175 0.47661 0.39895 0.07132  0.18649  -0.01696 79  GLN A CA    
634  C  C     . GLN A 86  ? 0.70951 0.45088 0.36762 0.06847  0.17875  -0.02424 79  GLN A C     
635  O  O     . GLN A 86  ? 0.79878 0.52107 0.43839 0.07355  0.18750  -0.02437 79  GLN A O     
636  C  CB    . GLN A 86  ? 0.66794 0.44783 0.36274 0.06867  0.19115  -0.01108 79  GLN A CB    
637  C  CG    . GLN A 86  ? 0.73990 0.55211 0.47228 0.06947  0.19753  -0.00290 79  GLN A CG    
638  C  CD    . GLN A 86  ? 0.93163 0.74607 0.65886 0.06594  0.20161  0.00308  79  GLN A CD    
639  O  OE1   . GLN A 86  ? 0.90905 0.70691 0.60945 0.05983  0.19332  0.00034  79  GLN A OE1   
640  N  NE2   . GLN A 86  ? 0.98775 0.82264 0.74093 0.06940  0.21367  0.01184  79  GLN A NE2   
641  N  N     . LEU A 87  ? 0.66965 0.40329 0.31479 0.06011  0.16219  -0.02970 80  LEU A N     
642  C  CA    . LEU A 87  ? 0.70221 0.40545 0.31141 0.05522  0.15217  -0.03554 80  LEU A CA    
643  C  C     . LEU A 87  ? 0.69903 0.39201 0.30518 0.05600  0.14701  -0.04102 80  LEU A C     
644  O  O     . LEU A 87  ? 0.75314 0.42163 0.33146 0.05075  0.13699  -0.04566 80  LEU A O     
645  C  CB    . LEU A 87  ? 0.67296 0.37344 0.26986 0.04475  0.13519  -0.03733 80  LEU A CB    
646  C  CG    . LEU A 87  ? 0.73612 0.44311 0.33146 0.04283  0.13839  -0.03185 80  LEU A CG    
647  C  CD1   . LEU A 87  ? 0.80742 0.51574 0.39614 0.03302  0.12041  -0.03286 80  LEU A CD1   
648  C  CD2   . LEU A 87  ? 0.71111 0.39578 0.27953 0.04534  0.14709  -0.03040 80  LEU A CD2   
649  N  N     . HIS A 88  ? 0.61698 0.32797 0.25124 0.06187  0.15294  -0.04004 81  HIS A N     
650  C  CA    . HIS A 88  ? 0.66329 0.36631 0.29703 0.06245  0.14776  -0.04478 81  HIS A CA    
651  C  C     . HIS A 88  ? 0.71866 0.42756 0.36858 0.07336  0.16306  -0.04158 81  HIS A C     
652  O  O     . HIS A 88  ? 0.62610 0.35539 0.29953 0.07949  0.17504  -0.03529 81  HIS A O     
653  C  CB    . HIS A 88  ? 0.63007 0.35022 0.28309 0.05659  0.13430  -0.04749 81  HIS A CB    
654  C  CG    . HIS A 88  ? 0.74158 0.45340 0.37688 0.04572  0.11745  -0.05061 81  HIS A CG    
655  N  ND1   . HIS A 88  ? 0.71864 0.44112 0.35656 0.04185  0.11458  -0.04766 81  HIS A ND1   
656  C  CD2   . HIS A 88  ? 0.76341 0.45690 0.37783 0.03763  0.10224  -0.05542 81  HIS A CD2   
657  C  CE1   . HIS A 88  ? 0.68922 0.40115 0.30955 0.03234  0.09792  -0.05049 81  HIS A CE1   
658  N  NE2   . HIS A 88  ? 0.79996 0.49526 0.40705 0.02932  0.08991  -0.05500 81  HIS A NE2   
659  N  N     . HIS A 89  ? 0.69370 0.38409 0.33050 0.07544  0.16225  -0.04527 82  HIS A N     
660  C  CA    . HIS A 89  ? 0.67340 0.36610 0.32220 0.08607  0.17614  -0.04210 82  HIS A CA    
661  C  C     . HIS A 89  ? 0.74748 0.47160 0.43679 0.08955  0.17729  -0.03902 82  HIS A C     
662  O  O     . HIS A 89  ? 0.68527 0.41652 0.38417 0.08452  0.16560  -0.04266 82  HIS A O     
663  C  CB    . HIS A 89  ? 0.67330 0.33638 0.29577 0.08672  0.17390  -0.04689 82  HIS A CB    
664  C  CG    . HIS A 89  ? 0.71794 0.34887 0.30110 0.08529  0.17582  -0.04861 82  HIS A CG    
665  N  ND1   . HIS A 89  ? 0.74562 0.36656 0.31910 0.09399  0.19205  -0.04459 82  HIS A ND1   
666  C  CD2   . HIS A 89  ? 0.74035 0.34741 0.29198 0.07589  0.16319  -0.05334 82  HIS A CD2   
667  C  CE1   . HIS A 89  ? 0.78432 0.37486 0.32022 0.09033  0.18982  -0.04729 82  HIS A CE1   
668  N  NE2   . HIS A 89  ? 0.78174 0.36362 0.30407 0.07909  0.17194  -0.05244 82  HIS A NE2   
669  N  N     . ASP A 90  ? 0.72576 0.46857 0.43902 0.09792  0.19109  -0.03178 83  ASP A N     
670  C  CA    . ASP A 90  ? 0.70140 0.47663 0.45545 0.10078  0.19220  -0.02712 83  ASP A CA    
671  C  C     . ASP A 90  ? 0.73764 0.51202 0.49990 0.10257  0.18707  -0.03019 83  ASP A C     
672  O  O     . ASP A 90  ? 0.69133 0.44550 0.43711 0.10711  0.19109  -0.03203 83  ASP A O     
673  C  CB    . ASP A 90  ? 0.70626 0.49841 0.48199 0.10940  0.20771  -0.01799 83  ASP A CB    
674  C  CG    . ASP A 90  ? 0.78131 0.60879 0.60045 0.11088  0.20751  -0.01182 83  ASP A CG    
675  O  OD1   . ASP A 90  ? 0.74424 0.58842 0.57759 0.10419  0.19889  -0.01208 83  ASP A OD1   
676  O  OD2   . ASP A 90  ? 0.82320 0.66112 0.66179 0.11862  0.21557  -0.00640 83  ASP A OD2   
677  N  N     . GLN A 91  ? 0.64888 0.44458 0.43615 0.09899  0.17835  -0.03050 84  GLN A N     
678  C  CA    . GLN A 91  ? 0.57228 0.37236 0.37330 0.10066  0.17344  -0.03223 84  GLN A CA    
679  C  C     . GLN A 91  ? 0.63087 0.46126 0.46569 0.09781  0.16725  -0.02960 84  GLN A C     
680  O  O     . GLN A 91  ? 0.53041 0.37485 0.37406 0.09410  0.16633  -0.02724 84  GLN A O     
681  C  CB    . GLN A 91  ? 0.62288 0.39607 0.39512 0.09487  0.16250  -0.04077 84  GLN A CB    
682  C  CG    . GLN A 91  ? 0.66661 0.43590 0.42636 0.08411  0.14888  -0.04598 84  GLN A CG    
683  C  CD    . GLN A 91  ? 0.70037 0.44763 0.43807 0.07730  0.13617  -0.05320 84  GLN A CD    
684  O  OE1   . GLN A 91  ? 0.73219 0.48033 0.47921 0.07872  0.13335  -0.05450 84  GLN A OE1   
685  N  NE2   . GLN A 91  ? 0.61650 0.34346 0.32458 0.06946  0.12806  -0.05724 84  GLN A NE2   
686  N  N     . GLU A 92  ? 0.65670 0.49613 0.50960 0.09954  0.16308  -0.02972 85  GLU A N     
687  C  CA    . GLU A 92  ? 0.54974 0.41659 0.43433 0.09701  0.15679  -0.02704 85  GLU A CA    
688  C  C     . GLU A 92  ? 0.58140 0.44252 0.45485 0.08810  0.14407  -0.03379 85  GLU A C     
689  O  O     . GLU A 92  ? 0.56255 0.40098 0.41119 0.08419  0.13691  -0.04078 85  GLU A O     
690  C  CB    . GLU A 92  ? 0.59555 0.47302 0.50216 0.10184  0.15618  -0.02445 85  GLU A CB    
691  C  CG    . GLU A 92  ? 0.71112 0.60653 0.64164 0.10962  0.16694  -0.01508 85  GLU A CG    
692  C  CD    . GLU A 92  ? 0.86324 0.76724 0.81310 0.11466  0.16613  -0.01206 85  GLU A CD    
693  O  OE1   . GLU A 92  ? 0.85603 0.74023 0.78935 0.11923  0.16941  -0.01468 85  GLU A OE1   
694  O  OE2   . GLU A 92  ? 0.89567 0.82556 0.87660 0.11377  0.16180  -0.00676 85  GLU A OE2   
695  N  N     . TYR A 93  ? 0.48521 0.36992 0.38021 0.08203  0.13691  -0.03006 86  TYR A N     
696  C  CA    . TYR A 93  ? 0.48802 0.37478 0.37960 0.07063  0.12001  -0.03340 86  TYR A CA    
697  C  C     . TYR A 93  ? 0.48068 0.39262 0.40365 0.06654  0.10940  -0.03053 86  TYR A C     
698  O  O     . TYR A 93  ? 0.48045 0.41423 0.43008 0.06925  0.11332  -0.02413 86  TYR A O     
699  C  CB    . TYR A 93  ? 0.43411 0.32258 0.31794 0.06589  0.11934  -0.03175 86  TYR A CB    
700  C  CG    . TYR A 93  ? 0.48888 0.35042 0.33770 0.06869  0.12850  -0.03480 86  TYR A CG    
701  C  CD1   . TYR A 93  ? 0.53271 0.36624 0.34977 0.06621  0.12357  -0.04203 86  TYR A CD1   
702  C  CD2   . TYR A 93  ? 0.54301 0.40621 0.38948 0.07330  0.14186  -0.03016 86  TYR A CD2   
703  C  CE1   . TYR A 93  ? 0.51718 0.32298 0.29855 0.06843  0.13146  -0.04512 86  TYR A CE1   
704  C  CE2   . TYR A 93  ? 0.56115 0.39756 0.37256 0.07618  0.15103  -0.03298 86  TYR A CE2   
705  C  CZ    . TYR A 93  ? 0.62397 0.43260 0.40409 0.07299  0.14406  -0.04015 86  TYR A CZ    
706  O  OH    . TYR A 93  ? 0.63628 0.42125 0.38610 0.07310  0.14789  -0.04127 86  TYR A OH    
707  N  N     . LYS A 94  ? 0.41568 0.32394 0.33465 0.05965  0.09584  -0.03490 87  LYS A N     
708  C  CA    . LYS A 94  ? 0.37112 0.30008 0.31410 0.05428  0.08438  -0.03299 87  LYS A CA    
709  C  C     . LYS A 94  ? 0.37566 0.30591 0.31220 0.04568  0.07366  -0.03439 87  LYS A C     
710  O  O     . LYS A 94  ? 0.43389 0.34762 0.34881 0.04135  0.06771  -0.03895 87  LYS A O     
711  C  CB    . LYS A 94  ? 0.42828 0.35334 0.37358 0.05384  0.07832  -0.03589 87  LYS A CB    
712  C  CG    . LYS A 94  ? 0.53448 0.45909 0.48804 0.06298  0.08842  -0.03378 87  LYS A CG    
713  C  CD    . LYS A 94  ? 0.65102 0.57376 0.60936 0.06206  0.08167  -0.03573 87  LYS A CD    
714  C  CE    . LYS A 94  ? 0.78821 0.71156 0.75649 0.07183  0.09150  -0.03270 87  LYS A CE    
715  N  NZ    . LYS A 94  ? 0.92331 0.85732 0.90917 0.07058  0.08395  -0.03123 87  LYS A NZ    
716  N  N     . VAL A 95  ? 0.32143 0.27038 0.27612 0.04321  0.07111  -0.03004 88  VAL A N     
717  C  CA    . VAL A 95  ? 0.30454 0.25590 0.25526 0.03636  0.06214  -0.03030 88  VAL A CA    
718  C  C     . VAL A 95  ? 0.33867 0.30510 0.30807 0.03215  0.05137  -0.02959 88  VAL A C     
719  O  O     . VAL A 95  ? 0.29295 0.27333 0.28259 0.03413  0.05242  -0.02659 88  VAL A O     
720  C  CB    . VAL A 95  ? 0.34233 0.30006 0.29589 0.03674  0.06813  -0.02582 88  VAL A CB    
721  C  CG1   . VAL A 95  ? 0.31172 0.27044 0.26030 0.03017  0.05860  -0.02590 88  VAL A CG1   
722  C  CG2   . VAL A 95  ? 0.41437 0.35698 0.34900 0.04190  0.08088  -0.02598 88  VAL A CG2   
723  N  N     . THR A 96  ? 0.29975 0.26306 0.26201 0.02654  0.04112  -0.03192 89  THR A N     
724  C  CA    . THR A 96  ? 0.28599 0.26221 0.26347 0.02295  0.03175  -0.03105 89  THR A CA    
725  C  C     . THR A 96  ? 0.29808 0.27772 0.27394 0.01916  0.02644  -0.02945 89  THR A C     
726  O  O     . THR A 96  ? 0.32391 0.29277 0.28279 0.01711  0.02476  -0.03067 89  THR A O     
727  C  CB    . THR A 96  ? 0.35745 0.32833 0.33069 0.02032  0.02451  -0.03434 89  THR A CB    
728  O  OG1   . THR A 96  ? 0.36333 0.32859 0.33616 0.02400  0.02953  -0.03584 89  THR A OG1   
729  C  CG2   . THR A 96  ? 0.31859 0.30320 0.30796 0.01767  0.01665  -0.03291 89  THR A CG2   
730  N  N     . TRP A 97  ? 0.27672 0.26973 0.26875 0.01828  0.02360  -0.02660 90  TRP A N     
731  C  CA    . TRP A 97  ? 0.31604 0.31233 0.30829 0.01526  0.01800  -0.02491 90  TRP A CA    
732  C  C     . TRP A 97  ? 0.31631 0.31983 0.31823 0.01358  0.00993  -0.02522 90  TRP A C     
733  O  O     . TRP A 97  ? 0.27069 0.28128 0.28467 0.01464  0.00987  -0.02504 90  TRP A O     
734  C  CB    . TRP A 97  ? 0.24369 0.24733 0.24507 0.01554  0.02188  -0.02093 90  TRP A CB    
735  C  CG    . TRP A 97  ? 0.30738 0.30633 0.30136 0.01696  0.03044  -0.01899 90  TRP A CG    
736  C  CD1   . TRP A 97  ? 0.29679 0.28369 0.27433 0.01879  0.03596  -0.02088 90  TRP A CD1   
737  C  CD2   . TRP A 97  ? 0.29281 0.29837 0.29501 0.01650  0.03491  -0.01435 90  TRP A CD2   
738  N  NE1   . TRP A 97  ? 0.30964 0.29578 0.28480 0.02031  0.04475  -0.01757 90  TRP A NE1   
739  C  CE2   . TRP A 97  ? 0.33890 0.33751 0.33043 0.01861  0.04407  -0.01320 90  TRP A CE2   
740  C  CE3   . TRP A 97  ? 0.26758 0.28326 0.28434 0.01414  0.03200  -0.01086 90  TRP A CE3   
741  C  CZ2   . TRP A 97  ? 0.33208 0.33571 0.32925 0.01839  0.05077  -0.00804 90  TRP A CZ2   
742  C  CZ3   . TRP A 97  ? 0.27838 0.29822 0.30038 0.01311  0.03740  -0.00597 90  TRP A CZ3   
743  C  CH2   . TRP A 97  ? 0.31692 0.33186 0.33031 0.01522  0.04692  -0.00427 90  TRP A CH2   
744  N  N     . TYR A 98  ? 0.29505 0.29697 0.29180 0.01131  0.00346  -0.02508 91  TYR A N     
745  C  CA    . TYR A 98  ? 0.27608 0.28561 0.28248 0.01075  -0.00255 -0.02401 91  TYR A CA    
746  C  C     . TYR A 98  ? 0.28870 0.29882 0.29443 0.01050  -0.00339 -0.02132 91  TYR A C     
747  O  O     . TYR A 98  ? 0.27706 0.28153 0.27252 0.00939  -0.00537 -0.02055 91  TYR A O     
748  C  CB    . TYR A 98  ? 0.26026 0.26854 0.26315 0.00889  -0.00914 -0.02475 91  TYR A CB    
749  C  CG    . TYR A 98  ? 0.31602 0.32213 0.31835 0.00803  -0.00961 -0.02715 91  TYR A CG    
750  C  CD1   . TYR A 98  ? 0.27688 0.28750 0.28873 0.00974  -0.00678 -0.02792 91  TYR A CD1   
751  C  CD2   . TYR A 98  ? 0.40791 0.40608 0.39892 0.00498  -0.01355 -0.02837 91  TYR A CD2   
752  C  CE1   . TYR A 98  ? 0.30461 0.31180 0.31505 0.00891  -0.00718 -0.02989 91  TYR A CE1   
753  C  CE2   . TYR A 98  ? 0.38860 0.38258 0.37755 0.00347  -0.01436 -0.03053 91  TYR A CE2   
754  C  CZ    . TYR A 98  ? 0.38341 0.38195 0.38233 0.00571  -0.01082 -0.03126 91  TYR A CZ    
755  O  OH    . TYR A 98  ? 0.41670 0.40995 0.41305 0.00425  -0.01157 -0.03313 91  TYR A OH    
756  N  N     . VAL A 99  ? 0.23871 0.25406 0.25380 0.01113  -0.00237 -0.01972 92  VAL A N     
757  C  CA    . VAL A 99  ? 0.24522 0.25906 0.25874 0.01047  -0.00277 -0.01708 92  VAL A CA    
758  C  C     . VAL A 99  ? 0.26253 0.27884 0.28156 0.01138  -0.00724 -0.01634 92  VAL A C     
759  O  O     . VAL A 99  ? 0.25321 0.27367 0.27978 0.01220  -0.00788 -0.01732 92  VAL A O     
760  C  CB    . VAL A 99  ? 0.32794 0.34332 0.34561 0.00954  0.00255  -0.01507 92  VAL A CB    
761  C  CG1   . VAL A 99  ? 0.43243 0.44433 0.44331 0.00979  0.00865  -0.01504 92  VAL A CG1   
762  C  CG2   . VAL A 99  ? 0.34768 0.36983 0.37756 0.00975  0.00300  -0.01514 92  VAL A CG2   
763  N  N     . SER A 100 ? 0.24791 0.26041 0.26203 0.01168  -0.00988 -0.01438 93  SER A N     
764  C  CA    . SER A 100 ? 0.20406 0.21710 0.22174 0.01390  -0.01316 -0.01364 93  SER A CA    
765  C  C     . SER A 100 ? 0.29622 0.30750 0.31717 0.01322  -0.01209 -0.01323 93  SER A C     
766  O  O     . SER A 100 ? 0.28316 0.29528 0.30787 0.01485  -0.01320 -0.01409 93  SER A O     
767  C  CB    . SER A 100 ? 0.26880 0.27779 0.28053 0.01534  -0.01632 -0.01119 93  SER A CB    
768  O  OG    . SER A 100 ? 0.27150 0.27426 0.27586 0.01339  -0.01490 -0.00939 93  SER A OG    
769  N  N     . TRP A 101 ? 0.27253 0.28070 0.29132 0.01040  -0.01010 -0.01156 94  TRP A N     
770  C  CA    . TRP A 101 ? 0.28751 0.29438 0.30989 0.00783  -0.00992 -0.01054 94  TRP A CA    
771  C  C     . TRP A 101 ? 0.36129 0.37458 0.39054 0.00529  -0.00627 -0.00992 94  TRP A C     
772  O  O     . TRP A 101 ? 0.27041 0.28512 0.29775 0.00512  -0.00248 -0.00932 94  TRP A O     
773  C  CB    . TRP A 101 ? 0.22120 0.21994 0.23740 0.00577  -0.01078 -0.00775 94  TRP A CB    
774  C  CG    . TRP A 101 ? 0.24489 0.23492 0.25461 0.00849  -0.01405 -0.00757 94  TRP A CG    
775  C  CD1   . TRP A 101 ? 0.30346 0.28723 0.30571 0.01031  -0.01507 -0.00575 94  TRP A CD1   
776  C  CD2   . TRP A 101 ? 0.26434 0.24932 0.27317 0.01011  -0.01620 -0.00885 94  TRP A CD2   
777  N  NE1   . TRP A 101 ? 0.27111 0.24687 0.26915 0.01371  -0.01725 -0.00567 94  TRP A NE1   
778  C  CE2   . TRP A 101 ? 0.30685 0.28246 0.30784 0.01370  -0.01758 -0.00781 94  TRP A CE2   
779  C  CE3   . TRP A 101 ? 0.28044 0.26678 0.29304 0.00919  -0.01698 -0.01060 94  TRP A CE3   
780  C  CZ2   . TRP A 101 ? 0.28480 0.25160 0.28094 0.01697  -0.01864 -0.00878 94  TRP A CZ2   
781  C  CZ3   . TRP A 101 ? 0.28479 0.26190 0.29129 0.01165  -0.01869 -0.01171 94  TRP A CZ3   
782  C  CH2   . TRP A 101 ? 0.28430 0.25132 0.28229 0.01577  -0.01899 -0.01094 94  TRP A CH2   
783  N  N     . SER A 102 ? 0.26460 0.28106 0.30118 0.00355  -0.00727 -0.00961 95  SER A N     
784  C  CA    . SER A 102 ? 0.30431 0.32817 0.34995 0.00142  -0.00398 -0.00757 95  SER A CA    
785  C  C     . SER A 102 ? 0.27126 0.29448 0.31733 -0.00229 -0.00164 -0.00335 95  SER A C     
786  O  O     . SER A 102 ? 0.32007 0.33569 0.35910 -0.00407 -0.00389 -0.00220 95  SER A O     
787  C  CB    . SER A 102 ? 0.24447 0.27187 0.29799 -0.00011 -0.00713 -0.00731 95  SER A CB    
788  O  OG    . SER A 102 ? 0.25359 0.27415 0.30368 -0.00342 -0.01198 -0.00617 95  SER A OG    
789  N  N     . PRO A 103 ? 0.29166 0.32265 0.34613 -0.00318 0.00345  -0.00049 96  PRO A N     
790  C  CA    . PRO A 103 ? 0.27614 0.30759 0.33123 -0.00625 0.00743  0.00416  96  PRO A CA    
791  C  C     . PRO A 103 ? 0.37983 0.40984 0.43892 -0.01234 0.00290  0.00812  96  PRO A C     
792  O  O     . PRO A 103 ? 0.29603 0.32952 0.36324 -0.01506 -0.00164 0.00911  96  PRO A O     
793  C  CB    . PRO A 103 ? 0.31007 0.35171 0.37563 -0.00461 0.01470  0.00666  96  PRO A CB    
794  C  CG    . PRO A 103 ? 0.28251 0.32422 0.34579 0.00041  0.01534  0.00179  96  PRO A CG    
795  C  CD    . PRO A 103 ? 0.26221 0.30089 0.32417 -0.00011 0.00739  -0.00135 96  PRO A CD    
796  N  N     . CYS A 104 ? 0.29569 0.31938 0.34791 -0.01501 0.00375  0.01070  97  CYS A N     
797  C  CA    . CYS A 104 ? 0.34902 0.37083 0.40502 -0.02196 0.00019  0.01548  97  CYS A CA    
798  C  C     . CYS A 104 ? 0.34650 0.38220 0.41948 -0.02538 0.00426  0.02158  97  CYS A C     
799  O  O     . CYS A 104 ? 0.32221 0.36762 0.40259 -0.02124 0.01087  0.02187  97  CYS A O     
800  C  CB    . CYS A 104 ? 0.35703 0.36812 0.40128 -0.02393 0.00057  0.01726  97  CYS A CB    
801  S  SG    . CYS A 104 ? 0.37683 0.39266 0.42090 -0.02352 0.01080  0.02167  97  CYS A SG    
802  N  N     . THR A 105 ? 0.34450 0.38078 0.42392 -0.03305 0.00018  0.02698  98  THR A N     
803  C  CA    . THR A 105 ? 0.35731 0.40906 0.45643 -0.03710 0.00257  0.03418  98  THR A CA    
804  C  C     . THR A 105 ? 0.34642 0.40625 0.45040 -0.03469 0.01400  0.03850  98  THR A C     
805  O  O     . THR A 105 ? 0.37472 0.44893 0.49392 -0.03229 0.02026  0.04224  98  THR A O     
806  C  CB    . THR A 105 ? 0.33994 0.38913 0.44356 -0.04729 -0.00536 0.03963  98  THR A CB    
807  O  OG1   . THR A 105 ? 0.35958 0.39891 0.45305 -0.05064 -0.00380 0.04176  98  THR A OG1   
808  C  CG2   . THR A 105 ? 0.33974 0.37690 0.43393 -0.04929 -0.01621 0.03479  98  THR A CG2   
809  N  N     . ARG A 106 ? 0.36284 0.41270 0.45322 -0.03486 0.01722  0.03838  99  ARG A N     
810  C  CA    . ARG A 106 ? 0.42053 0.47517 0.51179 -0.03284 0.02853  0.04260  99  ARG A CA    
811  C  C     . ARG A 106 ? 0.37074 0.42708 0.45727 -0.02370 0.03630  0.03791  99  ARG A C     
812  O  O     . ARG A 106 ? 0.34064 0.40696 0.43633 -0.02058 0.04613  0.04174  99  ARG A O     
813  C  CB    . ARG A 106 ? 0.35918 0.40021 0.43397 -0.03530 0.02888  0.04322  99  ARG A CB    
814  C  CG    . ARG A 106 ? 0.46013 0.49856 0.53937 -0.04504 0.02294  0.04925  99  ARG A CG    
815  C  CD    . ARG A 106 ? 0.53928 0.56386 0.60231 -0.04728 0.02417  0.05077  99  ARG A CD    
816  N  NE    . ARG A 106 ? 0.48908 0.51080 0.55667 -0.05733 0.01942  0.05748  99  ARG A NE    
817  C  CZ    . ARG A 106 ? 0.66742 0.68187 0.73478 -0.06317 0.00850  0.05669  99  ARG A CZ    
818  N  NH1   . ARG A 106 ? 0.48676 0.49615 0.54936 -0.05949 0.00167  0.04952  99  ARG A NH1   
819  N  NH2   . ARG A 106 ? 0.74363 0.75433 0.81412 -0.07321 0.00445  0.06338  99  ARG A NH2   
820  N  N     . CYS A 107 ? 0.35699 0.40297 0.42887 -0.01930 0.03224  0.02997  100 CYS A N     
821  C  CA    . CYS A 107 ? 0.36553 0.41070 0.43089 -0.01179 0.03805  0.02520  100 CYS A CA    
822  C  C     . CYS A 107 ? 0.35689 0.41415 0.43806 -0.00884 0.03987  0.02550  100 CYS A C     
823  O  O     . CYS A 107 ? 0.36703 0.42790 0.44956 -0.00349 0.04891  0.02575  100 CYS A O     
824  C  CB    . CYS A 107 ? 0.27884 0.31199 0.32785 -0.00904 0.03171  0.01776  100 CYS A CB    
825  S  SG    . CYS A 107 ? 0.32159 0.34037 0.35008 -0.00982 0.03160  0.01748  100 CYS A SG    
826  N  N     . ALA A 108 ? 0.33170 0.39380 0.42344 -0.01199 0.03142  0.02555  101 ALA A N     
827  C  CA    . ALA A 108 ? 0.38157 0.45489 0.48830 -0.00932 0.03203  0.02633  101 ALA A CA    
828  C  C     . ALA A 108 ? 0.37285 0.46029 0.49689 -0.00887 0.04095  0.03438  101 ALA A C     
829  O  O     . ALA A 108 ? 0.34601 0.44003 0.47703 -0.00274 0.04774  0.03473  101 ALA A O     
830  C  CB    . ALA A 108 ? 0.31566 0.39053 0.42919 -0.01395 0.02081  0.02602  101 ALA A CB    
831  N  N     . ASN A 109 ? 0.34763 0.43949 0.47869 -0.01502 0.04170  0.04138  102 ASN A N     
832  C  CA    . ASN A 109 ? 0.36690 0.47436 0.51706 -0.01488 0.05076  0.05057  102 ASN A CA    
833  C  C     . ASN A 109 ? 0.41873 0.52318 0.55989 -0.00766 0.06519  0.05047  102 ASN A C     
834  O  O     . ASN A 109 ? 0.41129 0.52669 0.56517 -0.00220 0.07521  0.05492  102 ASN A O     
835  C  CB    . ASN A 109 ? 0.45785 0.57080 0.61838 -0.02474 0.04676  0.05872  102 ASN A CB    
836  C  CG    . ASN A 109 ? 0.61885 0.74206 0.79765 -0.03145 0.03581  0.06304  102 ASN A CG    
837  O  OD1   . ASN A 109 ? 0.59956 0.74068 0.80154 -0.03197 0.03860  0.07118  102 ASN A OD1   
838  N  ND2   . ASN A 109 ? 0.49401 0.60542 0.66196 -0.03642 0.02329  0.05799  102 ASN A ND2   
839  N  N     . SER A 110 ? 0.39666 0.48550 0.51513 -0.00724 0.06662  0.04581  103 SER A N     
840  C  CA    . SER A 110 ? 0.37312 0.45557 0.47841 -0.00072 0.07963  0.04507  103 SER A CA    
841  C  C     . SER A 110 ? 0.41572 0.49414 0.51460 0.00792  0.08366  0.03885  103 SER A C     
842  O  O     . SER A 110 ? 0.42502 0.50484 0.52376 0.01454  0.09628  0.04083  103 SER A O     
843  C  CB    . SER A 110 ? 0.39454 0.45990 0.47536 -0.00268 0.07812  0.04134  103 SER A CB    
844  O  OG    . SER A 110 ? 0.52830 0.59462 0.61289 -0.01077 0.07352  0.04658  103 SER A OG    
845  N  N     . VAL A 111 ? 0.40809 0.48021 0.50046 0.00812  0.07364  0.03146  104 VAL A N     
846  C  CA    . VAL A 111 ? 0.30448 0.37204 0.39090 0.01528  0.07639  0.02577  104 VAL A CA    
847  C  C     . VAL A 111 ? 0.46877 0.55157 0.57766 0.01897  0.08094  0.03070  104 VAL A C     
848  O  O     . VAL A 111 ? 0.43643 0.51780 0.54357 0.02660  0.09091  0.03029  104 VAL A O     
849  C  CB    . VAL A 111 ? 0.30217 0.36116 0.37863 0.01389  0.06450  0.01789  104 VAL A CB    
850  C  CG1   . VAL A 111 ? 0.25661 0.31134 0.32857 0.02028  0.06667  0.01269  104 VAL A CG1   
851  C  CG2   . VAL A 111 ? 0.28773 0.33270 0.34333 0.01136  0.06049  0.01392  104 VAL A CG2   
852  N  N     . ALA A 112 ? 0.39273 0.48924 0.52219 0.01368  0.07338  0.03567  105 ALA A N     
853  C  CA    . ALA A 112 ? 0.39931 0.51235 0.55272 0.01642  0.07619  0.04191  105 ALA A CA    
854  C  C     . ALA A 112 ? 0.41400 0.53585 0.57723 0.02151  0.09144  0.04954  105 ALA A C     
855  O  O     . ALA A 112 ? 0.42819 0.55557 0.60005 0.02946  0.09967  0.05145  105 ALA A O     
856  C  CB    . ALA A 112 ? 0.33460 0.45974 0.50656 0.00792  0.06455  0.04715  105 ALA A CB    
857  N  N     . THR A 113 ? 0.43093 0.55348 0.59246 0.01755  0.09611  0.05426  106 THR A N     
858  C  CA    . THR A 113 ? 0.38075 0.51144 0.55073 0.02254  0.11210  0.06212  106 THR A CA    
859  C  C     . THR A 113 ? 0.49144 0.60654 0.63942 0.03274  0.12464  0.05626  106 THR A C     
860  O  O     . THR A 113 ? 0.50509 0.62618 0.66134 0.04117  0.13828  0.06081  106 THR A O     
861  C  CB    . THR A 113 ? 0.48242 0.61479 0.65215 0.01524  0.11386  0.06804  106 THR A CB    
862  O  OG1   . THR A 113 ? 0.51683 0.66267 0.70704 0.00525  0.10221  0.07414  106 THR A OG1   
863  C  CG2   . THR A 113 ? 0.46630 0.60682 0.64381 0.02068  0.13185  0.07661  106 THR A CG2   
864  N  N     . PHE A 114 ? 0.45139 0.54574 0.57082 0.03215  0.12018  0.04653  107 PHE A N     
865  C  CA    . PHE A 114 ? 0.43945 0.51584 0.53449 0.04041  0.13001  0.04037  107 PHE A CA    
866  C  C     . PHE A 114 ? 0.48908 0.56510 0.58821 0.04788  0.13138  0.03700  107 PHE A C     
867  O  O     . PHE A 114 ? 0.48694 0.55781 0.58081 0.05702  0.14488  0.03757  107 PHE A O     
868  C  CB    . PHE A 114 ? 0.46593 0.52170 0.53160 0.03662  0.12211  0.03153  107 PHE A CB    
869  C  CG    . PHE A 114 ? 0.48022 0.51614 0.52063 0.04295  0.12575  0.02326  107 PHE A CG    
870  C  CD1   . PHE A 114 ? 0.55123 0.57349 0.57184 0.04876  0.13952  0.02308  107 PHE A CD1   
871  C  CD2   . PHE A 114 ? 0.41767 0.44741 0.45293 0.04270  0.11546  0.01592  107 PHE A CD2   
872  C  CE1   . PHE A 114 ? 0.55242 0.55366 0.54723 0.05376  0.14204  0.01532  107 PHE A CE1   
873  C  CE2   . PHE A 114 ? 0.57359 0.58428 0.58547 0.04731  0.11787  0.00872  107 PHE A CE2   
874  C  CZ    . PHE A 114 ? 0.48236 0.47792 0.47316 0.05260  0.13075  0.00823  107 PHE A CZ    
875  N  N     . LEU A 115 ? 0.44958 0.52954 0.55669 0.04443  0.11797  0.03354  108 LEU A N     
876  C  CA    . LEU A 115 ? 0.43509 0.51430 0.54609 0.05083  0.11817  0.03062  108 LEU A CA    
877  C  C     . LEU A 115 ? 0.56091 0.65839 0.69855 0.05691  0.12751  0.03993  108 LEU A C     
878  O  O     . LEU A 115 ? 0.51604 0.60907 0.65194 0.06630  0.13656  0.03921  108 LEU A O     
879  C  CB    . LEU A 115 ? 0.36177 0.44272 0.47689 0.04516  0.10196  0.02618  108 LEU A CB    
880  C  CG    . LEU A 115 ? 0.39568 0.45896 0.48638 0.04156  0.09297  0.01660  108 LEU A CG    
881  C  CD1   . LEU A 115 ? 0.34579 0.41366 0.44446 0.03694  0.07896  0.01392  108 LEU A CD1   
882  C  CD2   . LEU A 115 ? 0.38417 0.42870 0.45218 0.04811  0.09969  0.01011  108 LEU A CD2   
883  N  N     . ALA A 116 ? 0.48757 0.60546 0.65037 0.05160  0.12510  0.04920  109 ALA A N     
884  C  CA    . ALA A 116 ? 0.57407 0.71205 0.76554 0.05607  0.13108  0.05924  109 ALA A CA    
885  C  C     . ALA A 116 ? 0.52333 0.65541 0.70691 0.06398  0.14579  0.06203  109 ALA A C     
886  O  O     . ALA A 116 ? 0.58127 0.71784 0.77451 0.07009  0.14905  0.06567  109 ALA A O     
887  C  CB    . ALA A 116 ? 0.53495 0.69320 0.75133 0.04618  0.12224  0.06829  109 ALA A CB    
888  N  N     . LYS A 117 ? 0.49279 0.61397 0.65810 0.06418  0.15487  0.06067  110 LYS A N     
889  C  CA    . LYS A 117 ? 0.64298 0.75729 0.79915 0.07133  0.16900  0.06355  110 LYS A CA    
890  C  C     . LYS A 117 ? 0.57230 0.65992 0.69574 0.07930  0.17686  0.05419  110 LYS A C     
891  O  O     . LYS A 117 ? 0.67960 0.75632 0.78843 0.08461  0.18871  0.05514  110 LYS A O     
892  C  CB    . LYS A 117 ? 0.64441 0.76308 0.80066 0.06623  0.17445  0.06936  110 LYS A CB    
893  C  CG    . LYS A 117 ? 0.67356 0.81746 0.86185 0.05865  0.16849  0.08034  110 LYS A CG    
894  C  CD    . LYS A 117 ? 0.68472 0.83153 0.87205 0.04860  0.16580  0.08312  110 LYS A CD    
895  C  CE    . LYS A 117 ? 0.79580 0.92069 0.95050 0.05082  0.17497  0.07696  110 LYS A CE    
896  N  NZ    . LYS A 117 ? 0.81193 0.94000 0.96640 0.04314  0.17727  0.08294  110 LYS A NZ    
897  N  N     . ASP A 118 ? 0.60172 0.67747 0.71235 0.07984  0.17014  0.04529  111 ASP A N     
898  C  CA    . ASP A 118 ? 0.62690 0.67541 0.70498 0.08595  0.17536  0.03606  111 ASP A CA    
899  C  C     . ASP A 118 ? 0.52839 0.57298 0.60818 0.08910  0.16870  0.03110  111 ASP A C     
900  O  O     . ASP A 118 ? 0.52731 0.56927 0.60382 0.08502  0.15908  0.02520  111 ASP A O     
901  C  CB    . ASP A 118 ? 0.57280 0.60378 0.62307 0.08155  0.17398  0.02869  111 ASP A CB    
902  C  CG    . ASP A 118 ? 0.65612 0.65692 0.66968 0.08656  0.17918  0.02019  111 ASP A CG    
903  O  OD1   . ASP A 118 ? 0.60969 0.60235 0.61970 0.09313  0.18217  0.01860  111 ASP A OD1   
904  O  OD2   . ASP A 118 ? 0.64163 0.62575 0.62878 0.08341  0.17957  0.01538  111 ASP A OD2   
905  N  N     . PRO A 119 ? 0.53700 0.58008 0.62101 0.09657  0.17401  0.03348  112 PRO A N     
906  C  CA    . PRO A 119 ? 0.57047 0.60967 0.65639 0.09944  0.16783  0.02955  112 PRO A CA    
907  C  C     . PRO A 119 ? 0.58557 0.59654 0.63867 0.10111  0.16708  0.01846  112 PRO A C     
908  O  O     . PRO A 119 ? 0.55327 0.55987 0.60647 0.10216  0.16077  0.01452  112 PRO A O     
909  C  CB    . PRO A 119 ? 0.61035 0.65544 0.70921 0.10729  0.17564  0.03659  112 PRO A CB    
910  C  CG    . PRO A 119 ? 0.61169 0.64710 0.69604 0.11112  0.18872  0.03869  112 PRO A CG    
911  C  CD    . PRO A 119 ? 0.62442 0.66847 0.71117 0.10314  0.18650  0.04022  112 PRO A CD    
912  N  N     . LYS A 120 ? 0.52731 0.51831 0.55166 0.10067  0.17235  0.01352  113 LYS A N     
913  C  CA    . LYS A 120 ? 0.55617 0.51865 0.54752 0.10104  0.17018  0.00329  113 LYS A CA    
914  C  C     . LYS A 120 ? 0.52005 0.47857 0.50281 0.09356  0.15917  -0.00358 113 LYS A C     
915  O  O     . LYS A 120 ? 0.55489 0.49089 0.51194 0.09221  0.15458  -0.01196 113 LYS A O     
916  C  CB    . LYS A 120 ? 0.62826 0.56771 0.58906 0.10378  0.17988  0.00111  113 LYS A CB    
917  C  CG    . LYS A 120 ? 0.62548 0.56106 0.58761 0.11272  0.19133  0.00592  113 LYS A CG    
918  C  CD    . LYS A 120 ? 0.82155 0.72646 0.74662 0.11587  0.19909  0.00133  113 LYS A CD    
919  C  CE    . LYS A 120 ? 0.86388 0.75006 0.77584 0.12222  0.20160  -0.00182 113 LYS A CE    
920  N  NZ    . LYS A 120 ? 0.86561 0.71770 0.73712 0.12339  0.20587  -0.00788 113 LYS A NZ    
921  N  N     . VAL A 121 ? 0.43402 0.41350 0.43740 0.08613  0.15053  0.00020  114 VAL A N     
922  C  CA    . VAL A 121 ? 0.44121 0.41881 0.43778 0.07543  0.13379  -0.00500 114 VAL A CA    
923  C  C     . VAL A 121 ? 0.46495 0.46173 0.48776 0.07145  0.12198  -0.00302 114 VAL A C     
924  O  O     . VAL A 121 ? 0.39714 0.41547 0.44705 0.07185  0.12321  0.00452  114 VAL A O     
925  C  CB    . VAL A 121 ? 0.48384 0.46462 0.47589 0.06894  0.13188  -0.00307 114 VAL A CB    
926  C  CG1   . VAL A 121 ? 0.46968 0.44945 0.45681 0.05912  0.11485  -0.00779 114 VAL A CG1   
927  C  CG2   . VAL A 121 ? 0.45679 0.41663 0.41981 0.07265  0.14348  -0.00500 114 VAL A CG2   
928  N  N     . THR A 122 ? 0.40371 0.39211 0.41770 0.06725  0.11044  -0.00941 115 THR A N     
929  C  CA    . THR A 122 ? 0.40324 0.40550 0.43590 0.06268  0.09829  -0.00889 115 THR A CA    
930  C  C     . THR A 122 ? 0.34762 0.34730 0.37138 0.05360  0.08569  -0.01298 115 THR A C     
931  O  O     . THR A 122 ? 0.37063 0.35333 0.37107 0.05147  0.08376  -0.01839 115 THR A O     
932  C  CB    . THR A 122 ? 0.30523 0.29964 0.33589 0.06669  0.09706  -0.01212 115 THR A CB    
933  O  OG1   . THR A 122 ? 0.57124 0.57324 0.61720 0.07546  0.10751  -0.00651 115 THR A OG1   
934  C  CG2   . THR A 122 ? 0.46836 0.47155 0.51028 0.06072  0.08332  -0.01335 115 THR A CG2   
935  N  N     . LEU A 123 ? 0.30420 0.31994 0.34582 0.04836  0.07709  -0.01006 116 LEU A N     
936  C  CA    . LEU A 123 ? 0.27259 0.28726 0.30777 0.04092  0.06674  -0.01268 116 LEU A CA    
937  C  C     . LEU A 123 ? 0.29574 0.31873 0.34280 0.03725  0.05585  -0.01344 116 LEU A C     
938  O  O     . LEU A 123 ? 0.27501 0.31122 0.34108 0.03777  0.05482  -0.00922 116 LEU A O     
939  C  CB    . LEU A 123 ? 0.29905 0.32167 0.33956 0.03783  0.06829  -0.00810 116 LEU A CB    
940  C  CG    . LEU A 123 ? 0.29851 0.32111 0.33495 0.03093  0.05783  -0.00974 116 LEU A CG    
941  C  CD1   . LEU A 123 ? 0.26604 0.27228 0.27906 0.02957  0.05477  -0.01543 116 LEU A CD1   
942  C  CD2   . LEU A 123 ? 0.30495 0.33568 0.34888 0.02780  0.05943  -0.00431 116 LEU A CD2   
943  N  N     . THR A 124 ? 0.27595 0.29117 0.31162 0.03350  0.04776  -0.01830 117 THR A N     
944  C  CA    . THR A 124 ? 0.26913 0.29087 0.31322 0.02986  0.03798  -0.01908 117 THR A CA    
945  C  C     . THR A 124 ? 0.30950 0.33109 0.34843 0.02488  0.03143  -0.01984 117 THR A C     
946  O  O     . THR A 124 ? 0.25894 0.27081 0.28268 0.02363  0.03083  -0.02238 117 THR A O     
947  C  CB    . THR A 124 ? 0.30149 0.31527 0.33885 0.03041  0.03476  -0.02323 117 THR A CB    
948  O  OG1   . THR A 124 ? 0.31489 0.32699 0.35601 0.03579  0.04124  -0.02239 117 THR A OG1   
949  C  CG2   . THR A 124 ? 0.32044 0.34114 0.36614 0.02700  0.02585  -0.02349 117 THR A CG2   
950  N  N     . ILE A 125 ? 0.24540 0.27649 0.29583 0.02216  0.02630  -0.01743 118 ILE A N     
951  C  CA    . ILE A 125 ? 0.20119 0.23174 0.24764 0.01837  0.02052  -0.01764 118 ILE A CA    
952  C  C     . ILE A 125 ? 0.28039 0.31328 0.33060 0.01690  0.01310  -0.01922 118 ILE A C     
953  O  O     . ILE A 125 ? 0.28480 0.32411 0.34552 0.01653  0.01102  -0.01748 118 ILE A O     
954  C  CB    . ILE A 125 ? 0.24934 0.28590 0.30306 0.01632  0.02158  -0.01325 118 ILE A CB    
955  C  CG1   . ILE A 125 ? 0.24045 0.27638 0.29253 0.01829  0.03058  -0.01064 118 ILE A CG1   
956  C  CG2   . ILE A 125 ? 0.18985 0.22312 0.23730 0.01310  0.01595  -0.01360 118 ILE A CG2   
957  C  CD1   . ILE A 125 ? 0.30540 0.34963 0.36846 0.01586  0.03237  -0.00496 118 ILE A CD1   
958  N  N     . PHE A 126 ? 0.21097 0.23872 0.25255 0.01597  0.00910  -0.02197 119 PHE A N     
959  C  CA    . PHE A 126 ? 0.22702 0.25732 0.27176 0.01493  0.00311  -0.02263 119 PHE A CA    
960  C  C     . PHE A 126 ? 0.21889 0.24899 0.26156 0.01351  0.00012  -0.02128 119 PHE A C     
961  O  O     . PHE A 126 ? 0.26906 0.29491 0.30373 0.01291  0.00015  -0.02121 119 PHE A O     
962  C  CB    . PHE A 126 ? 0.24166 0.26827 0.28069 0.01461  0.00042  -0.02511 119 PHE A CB    
963  C  CG    . PHE A 126 ? 0.26431 0.28910 0.30427 0.01574  0.00242  -0.02660 119 PHE A CG    
964  C  CD1   . PHE A 126 ? 0.25262 0.28171 0.30053 0.01628  0.00086  -0.02632 119 PHE A CD1   
965  C  CD2   . PHE A 126 ? 0.29561 0.31243 0.32655 0.01645  0.00603  -0.02828 119 PHE A CD2   
966  C  CE1   . PHE A 126 ? 0.31558 0.34184 0.36374 0.01744  0.00258  -0.02740 119 PHE A CE1   
967  C  CE2   . PHE A 126 ? 0.34061 0.35339 0.37090 0.01790  0.00808  -0.02973 119 PHE A CE2   
968  C  CZ    . PHE A 126 ? 0.31395 0.33193 0.35358 0.01836  0.00619  -0.02912 119 PHE A CZ    
969  N  N     . VAL A 127 ? 0.25002 0.28290 0.29808 0.01308  -0.00264 -0.02020 120 VAL A N     
970  C  CA    . VAL A 127 ? 0.23361 0.26397 0.27854 0.01225  -0.00510 -0.01892 120 VAL A CA    
971  C  C     . VAL A 127 ? 0.25215 0.28193 0.29631 0.01375  -0.00866 -0.01975 120 VAL A C     
972  O  O     . VAL A 127 ? 0.23730 0.26928 0.28535 0.01454  -0.00940 -0.02055 120 VAL A O     
973  C  CB    . VAL A 127 ? 0.33778 0.36884 0.38697 0.01014  -0.00507 -0.01649 120 VAL A CB    
974  C  CG1   . VAL A 127 ? 0.29883 0.33355 0.35263 0.00924  -0.00046 -0.01452 120 VAL A CG1   
975  C  CG2   . VAL A 127 ? 0.31637 0.34856 0.36998 0.00983  -0.00800 -0.01660 120 VAL A CG2   
976  N  N     . ALA A 128 ? 0.20943 0.23633 0.24868 0.01458  -0.01042 -0.01902 121 ALA A N     
977  C  CA    . ALA A 128 ? 0.22877 0.25577 0.26849 0.01712  -0.01258 -0.01880 121 ALA A CA    
978  C  C     . ALA A 128 ? 0.21502 0.23750 0.25355 0.01777  -0.01301 -0.01841 121 ALA A C     
979  O  O     . ALA A 128 ? 0.18485 0.20728 0.22446 0.01968  -0.01314 -0.01897 121 ALA A O     
980  C  CB    . ALA A 128 ? 0.21454 0.24055 0.25064 0.01848  -0.01447 -0.01726 121 ALA A CB    
981  N  N     . ARG A 129 ? 0.23533 0.25275 0.27035 0.01579  -0.01322 -0.01731 122 ARG A N     
982  C  CA    . ARG A 129 ? 0.25970 0.26979 0.29091 0.01510  -0.01465 -0.01690 122 ARG A CA    
983  C  C     . ARG A 129 ? 0.27820 0.28822 0.31167 0.01019  -0.01501 -0.01557 122 ARG A C     
984  O  O     . ARG A 129 ? 0.29459 0.30838 0.33059 0.00841  -0.01307 -0.01435 122 ARG A O     
985  C  CB    . ARG A 129 ? 0.22345 0.22519 0.24712 0.01742  -0.01544 -0.01578 122 ARG A CB    
986  C  CG    . ARG A 129 ? 0.24252 0.24498 0.26572 0.02306  -0.01488 -0.01572 122 ARG A CG    
987  C  CD    . ARG A 129 ? 0.22710 0.22076 0.24324 0.02619  -0.01530 -0.01391 122 ARG A CD    
988  N  NE    . ARG A 129 ? 0.24405 0.23705 0.25832 0.02349  -0.01626 -0.01228 122 ARG A NE    
989  C  CZ    . ARG A 129 ? 0.27520 0.27442 0.29188 0.02406  -0.01679 -0.01109 122 ARG A CZ    
990  N  NH1   . ARG A 129 ? 0.22645 0.23371 0.24887 0.02676  -0.01715 -0.01096 122 ARG A NH1   
991  N  NH2   . ARG A 129 ? 0.22539 0.22224 0.23800 0.02128  -0.01723 -0.00967 122 ARG A NH2   
992  N  N     . LEU A 130 ? 0.22862 0.23389 0.26066 0.00788  -0.01754 -0.01534 123 LEU A N     
993  C  CA    . LEU A 130 ? 0.23151 0.23697 0.26692 0.00230  -0.01927 -0.01284 123 LEU A CA    
994  C  C     . LEU A 130 ? 0.26156 0.25652 0.28895 -0.00024 -0.02119 -0.01124 123 LEU A C     
995  O  O     . LEU A 130 ? 0.26320 0.24639 0.28071 0.00061  -0.02365 -0.01234 123 LEU A O     
996  C  CB    . LEU A 130 ? 0.23945 0.24469 0.27706 -0.00017 -0.02271 -0.01275 123 LEU A CB    
997  C  CG    . LEU A 130 ? 0.25583 0.27129 0.30225 0.00170  -0.02100 -0.01348 123 LEU A CG    
998  C  CD1   . LEU A 130 ? 0.25360 0.26679 0.29954 -0.00011 -0.02516 -0.01338 123 LEU A CD1   
999  C  CD2   . LEU A 130 ? 0.24068 0.26682 0.29808 0.00052  -0.01774 -0.01114 123 LEU A CD2   
1000 N  N     . TYR A 131 ? 0.25217 0.25014 0.28283 -0.00331 -0.01960 -0.00844 124 TYR A N     
1001 C  CA    . TYR A 131 ? 0.27968 0.26787 0.30307 -0.00625 -0.02105 -0.00627 124 TYR A CA    
1002 C  C     . TYR A 131 ? 0.29802 0.28205 0.32253 -0.01339 -0.02561 -0.00363 124 TYR A C     
1003 O  O     . TYR A 131 ? 0.26635 0.26067 0.30241 -0.01767 -0.02539 -0.00046 124 TYR A O     
1004 C  CB    . TYR A 131 ? 0.26821 0.26148 0.29404 -0.00672 -0.01691 -0.00393 124 TYR A CB    
1005 C  CG    . TYR A 131 ? 0.31946 0.30225 0.33636 -0.00849 -0.01763 -0.00170 124 TYR A CG    
1006 C  CD1   . TYR A 131 ? 0.28229 0.25308 0.28807 -0.00479 -0.01965 -0.00326 124 TYR A CD1   
1007 C  CD2   . TYR A 131 ? 0.35479 0.33966 0.37467 -0.01346 -0.01567 0.00255  124 TYR A CD2   
1008 C  CE1   . TYR A 131 ? 0.32004 0.27990 0.31701 -0.00606 -0.02041 -0.00091 124 TYR A CE1   
1009 C  CE2   . TYR A 131 ? 0.33062 0.30483 0.34151 -0.01550 -0.01638 0.00501  124 TYR A CE2   
1010 C  CZ    . TYR A 131 ? 0.36699 0.32832 0.36613 -0.01175 -0.01903 0.00312  124 TYR A CZ    
1011 O  OH    . TYR A 131 ? 0.46671 0.41643 0.45653 -0.01340 -0.01982 0.00581  124 TYR A OH    
1012 N  N     . TYR A 132 ? 0.28035 0.24884 0.29269 -0.01464 -0.02987 -0.00456 125 TYR A N     
1013 C  CA    . TYR A 132 ? 0.29325 0.25406 0.30325 -0.02268 -0.03592 -0.00206 125 TYR A CA    
1014 C  C     . TYR A 132 ? 0.28918 0.25976 0.30940 -0.02595 -0.03897 -0.00112 125 TYR A C     
1015 O  O     . TYR A 132 ? 0.32258 0.29911 0.35212 -0.03329 -0.04238 0.00343  125 TYR A O     
1016 C  CB    . TYR A 132 ? 0.30279 0.26441 0.31659 -0.02911 -0.03603 0.00292  125 TYR A CB    
1017 C  CG    . TYR A 132 ? 0.34174 0.28625 0.34073 -0.02870 -0.03653 0.00277  125 TYR A CG    
1018 C  CD1   . TYR A 132 ? 0.36930 0.29351 0.35231 -0.02998 -0.04152 0.00095  125 TYR A CD1   
1019 C  CD2   . TYR A 132 ? 0.36049 0.30753 0.35987 -0.02662 -0.03190 0.00449  125 TYR A CD2   
1020 C  CE1   . TYR A 132 ? 0.35742 0.26459 0.32636 -0.02874 -0.04156 0.00099  125 TYR A CE1   
1021 C  CE2   . TYR A 132 ? 0.34402 0.27524 0.33004 -0.02579 -0.03255 0.00486  125 TYR A CE2   
1022 C  CZ    . TYR A 132 ? 0.36624 0.27780 0.33772 -0.02662 -0.03722 0.00318  125 TYR A CZ    
1023 O  OH    . TYR A 132 ? 0.37669 0.27123 0.33444 -0.02506 -0.03750 0.00376  125 TYR A OH    
1024 N  N     . PHE A 133 ? 0.26549 0.23835 0.28482 -0.02049 -0.03784 -0.00476 126 PHE A N     
1025 C  CA    . PHE A 133 ? 0.28607 0.26878 0.31530 -0.02256 -0.04032 -0.00369 126 PHE A CA    
1026 C  C     . PHE A 133 ? 0.34634 0.31974 0.37046 -0.03041 -0.04900 -0.00160 126 PHE A C     
1027 O  O     . PHE A 133 ? 0.33977 0.32314 0.37520 -0.03440 -0.05259 0.00157  126 PHE A O     
1028 C  CB    . PHE A 133 ? 0.27471 0.25924 0.30164 -0.01539 -0.03748 -0.00793 126 PHE A CB    
1029 C  CG    . PHE A 133 ? 0.30301 0.27062 0.31234 -0.01202 -0.03863 -0.01170 126 PHE A CG    
1030 C  CD1   . PHE A 133 ? 0.39461 0.35043 0.39362 -0.01533 -0.04436 -0.01229 126 PHE A CD1   
1031 C  CD2   . PHE A 133 ? 0.30303 0.26618 0.30574 -0.00527 -0.03381 -0.01419 126 PHE A CD2   
1032 C  CE1   . PHE A 133 ? 0.36875 0.30702 0.34942 -0.01138 -0.04403 -0.01577 126 PHE A CE1   
1033 C  CE2   . PHE A 133 ? 0.33680 0.28497 0.32440 -0.00098 -0.03344 -0.01693 126 PHE A CE2   
1034 C  CZ    . PHE A 133 ? 0.34508 0.28014 0.32087 -0.00365 -0.03785 -0.01797 126 PHE A CZ    
1035 N  N     . TRP A 134 ? 0.32504 0.27875 0.33193 -0.03292 -0.05289 -0.00292 127 TRP A N     
1036 C  CA    . TRP A 134 ? 0.35701 0.29778 0.35483 -0.04119 -0.06223 -0.00139 127 TRP A CA    
1037 C  C     . TRP A 134 ? 0.36495 0.30816 0.37065 -0.05147 -0.06739 0.00473  127 TRP A C     
1038 O  O     . TRP A 134 ? 0.35908 0.29148 0.35786 -0.06021 -0.07667 0.00690  127 TRP A O     
1039 C  CB    . TRP A 134 ? 0.39508 0.30971 0.36720 -0.03876 -0.06377 -0.00606 127 TRP A CB    
1040 C  CG    . TRP A 134 ? 0.35515 0.25836 0.31820 -0.03696 -0.06060 -0.00661 127 TRP A CG    
1041 C  CD1   . TRP A 134 ? 0.37461 0.26332 0.32874 -0.04443 -0.06565 -0.00425 127 TRP A CD1   
1042 C  CD2   . TRP A 134 ? 0.32924 0.23466 0.29161 -0.02730 -0.05227 -0.00911 127 TRP A CD2   
1043 N  NE1   . TRP A 134 ? 0.41506 0.29602 0.36224 -0.03932 -0.06045 -0.00533 127 TRP A NE1   
1044 C  CE2   . TRP A 134 ? 0.38362 0.27530 0.33622 -0.02875 -0.05249 -0.00812 127 TRP A CE2   
1045 C  CE3   . TRP A 134 ? 0.37295 0.29063 0.34231 -0.01815 -0.04536 -0.01158 127 TRP A CE3   
1046 C  CZ2   . TRP A 134 ? 0.38212 0.27250 0.33206 -0.02078 -0.04618 -0.00930 127 TRP A CZ2   
1047 C  CZ3   . TRP A 134 ? 0.33166 0.24873 0.29903 -0.01106 -0.03963 -0.01261 127 TRP A CZ3   
1048 C  CH2   . TRP A 134 ? 0.36292 0.26663 0.32074 -0.01210 -0.04014 -0.01139 127 TRP A CH2   
1049 N  N     . LYS A 135 ? 0.32775 0.28379 0.34659 -0.05113 -0.06180 0.00788  128 LYS A N     
1050 C  CA    . LYS A 135 ? 0.35367 0.31197 0.38008 -0.06089 -0.06557 0.01440  128 LYS A CA    
1051 C  C     . LYS A 135 ? 0.40314 0.38565 0.45472 -0.06446 -0.06539 0.02082  128 LYS A C     
1052 O  O     . LYS A 135 ? 0.34572 0.34463 0.41002 -0.05756 -0.05715 0.02061  128 LYS A O     
1053 C  CB    . LYS A 135 ? 0.36331 0.31919 0.38726 -0.05876 -0.05923 0.01489  128 LYS A CB    
1054 C  CG    . LYS A 135 ? 0.42775 0.35849 0.42801 -0.05682 -0.06054 0.01066  128 LYS A CG    
1055 C  CD    . LYS A 135 ? 0.65329 0.57668 0.65094 -0.06335 -0.06140 0.01505  128 LYS A CD    
1056 C  CE    . LYS A 135 ? 0.62639 0.53273 0.60656 -0.05667 -0.05742 0.01135  128 LYS A CE    
1057 N  NZ    . LYS A 135 ? 0.61906 0.52995 0.60436 -0.05828 -0.05298 0.01566  128 LYS A NZ    
1058 N  N     . PRO A 136 ? 0.41934 0.40411 0.47839 -0.07502 -0.07432 0.02694  129 PRO A N     
1059 C  CA    . PRO A 136 ? 0.41762 0.42692 0.50279 -0.07764 -0.07442 0.03406  129 PRO A CA    
1060 C  C     . PRO A 136 ? 0.43557 0.46392 0.53899 -0.07397 -0.06360 0.03814  129 PRO A C     
1061 O  O     . PRO A 136 ? 0.38427 0.43150 0.50512 -0.06901 -0.05818 0.04036  129 PRO A O     
1062 C  CB    . PRO A 136 ? 0.49381 0.49937 0.58196 -0.09143 -0.08685 0.04096  129 PRO A CB    
1063 C  CG    . PRO A 136 ? 0.44090 0.41713 0.49969 -0.09377 -0.09468 0.03454  129 PRO A CG    
1064 C  CD    . PRO A 136 ? 0.42773 0.39168 0.47089 -0.08505 -0.08554 0.02779  129 PRO A CD    
1065 N  N     . ASP A 137 ? 0.37336 0.39553 0.47147 -0.07593 -0.05996 0.03919  130 ASP A N     
1066 C  CA    . ASP A 137 ? 0.42734 0.46486 0.53922 -0.07251 -0.04909 0.04303  130 ASP A CA    
1067 C  C     . ASP A 137 ? 0.43307 0.47586 0.54337 -0.06022 -0.03919 0.03705  130 ASP A C     
1068 O  O     . ASP A 137 ? 0.35644 0.41602 0.48202 -0.05605 -0.03088 0.04020  130 ASP A O     
1069 C  CB    . ASP A 137 ? 0.43221 0.45790 0.53356 -0.07629 -0.04746 0.04418  130 ASP A CB    
1070 C  CG    . ASP A 137 ? 0.57192 0.59802 0.68113 -0.08941 -0.05485 0.05274  130 ASP A CG    
1071 O  OD1   . ASP A 137 ? 0.49653 0.53360 0.62077 -0.09580 -0.06173 0.05824  130 ASP A OD1   
1072 O  OD2   . ASP A 137 ? 0.61975 0.63465 0.71986 -0.09375 -0.05450 0.05432  130 ASP A OD2   
1073 N  N     . TYR A 138 ? 0.35582 0.38368 0.44727 -0.05435 -0.03968 0.02875  131 TYR A N     
1074 C  CA    . TYR A 138 ? 0.32318 0.35496 0.41239 -0.04395 -0.03169 0.02332  131 TYR A CA    
1075 C  C     . TYR A 138 ? 0.35753 0.40052 0.45729 -0.04044 -0.03194 0.02269  131 TYR A C     
1076 O  O     . TYR A 138 ? 0.32308 0.37615 0.42979 -0.03383 -0.02433 0.02174  131 TYR A O     
1077 C  CB    . TYR A 138 ? 0.30375 0.31823 0.37235 -0.03907 -0.03238 0.01602  131 TYR A CB    
1078 C  CG    . TYR A 138 ? 0.36637 0.37097 0.42472 -0.03964 -0.02997 0.01630  131 TYR A CG    
1079 C  CD1   . TYR A 138 ? 0.37061 0.36374 0.42268 -0.04745 -0.03556 0.01943  131 TYR A CD1   
1080 C  CD2   . TYR A 138 ? 0.34556 0.35071 0.39914 -0.03285 -0.02295 0.01363  131 TYR A CD2   
1081 C  CE1   . TYR A 138 ? 0.38039 0.36329 0.42240 -0.04787 -0.03348 0.02004  131 TYR A CE1   
1082 C  CE2   . TYR A 138 ? 0.41678 0.41230 0.46030 -0.03333 -0.02137 0.01441  131 TYR A CE2   
1083 C  CZ    . TYR A 138 ? 0.39021 0.37471 0.42821 -0.04053 -0.02636 0.01762  131 TYR A CZ    
1084 O  OH    . TYR A 138 ? 0.38044 0.35432 0.40795 -0.04098 -0.02494 0.01878  131 TYR A OH    
1085 N  N     . GLN A 139 ? 0.31742 0.35682 0.41652 -0.04483 -0.04088 0.02313  132 GLN A N     
1086 C  CA    . GLN A 139 ? 0.35731 0.40733 0.46701 -0.04224 -0.04207 0.02367  132 GLN A CA    
1087 C  C     . GLN A 139 ? 0.36200 0.43285 0.49533 -0.04254 -0.03746 0.03114  132 GLN A C     
1088 O  O     . GLN A 139 ? 0.32076 0.40167 0.46247 -0.03553 -0.03123 0.03045  132 GLN A O     
1089 C  CB    . GLN A 139 ? 0.35783 0.39911 0.46146 -0.04846 -0.05360 0.02406  132 GLN A CB    
1090 C  CG    . GLN A 139 ? 0.43493 0.45397 0.51384 -0.04727 -0.05708 0.01694  132 GLN A CG    
1091 C  CD    . GLN A 139 ? 0.53272 0.53899 0.60159 -0.05484 -0.06873 0.01773  132 GLN A CD    
1092 O  OE1   . GLN A 139 ? 0.47895 0.49265 0.55955 -0.06292 -0.07591 0.02431  132 GLN A OE1   
1093 N  NE2   . GLN A 139 ? 0.43491 0.42142 0.48152 -0.05226 -0.07062 0.01142  132 GLN A NE2   
1094 N  N     . GLN A 140 ? 0.41057 0.48771 0.55498 -0.05056 -0.04017 0.03879  133 GLN A N     
1095 C  CA    . GLN A 140 ? 0.37451 0.47297 0.54360 -0.05071 -0.03501 0.04737  133 GLN A CA    
1096 C  C     . GLN A 140 ? 0.41350 0.51787 0.58452 -0.04194 -0.02106 0.04587  133 GLN A C     
1097 O  O     . GLN A 140 ? 0.37078 0.48899 0.55614 -0.03604 -0.01415 0.04861  133 GLN A O     
1098 C  CB    . GLN A 140 ? 0.48130 0.58486 0.66132 -0.06170 -0.04015 0.05633  133 GLN A CB    
1099 C  CG    . GLN A 140 ? 0.55064 0.67862 0.75952 -0.06244 -0.03486 0.06715  133 GLN A CG    
1100 C  CD    . GLN A 140 ? 0.72971 0.87199 0.95532 -0.05918 -0.03736 0.07046  133 GLN A CD    
1101 O  OE1   . GLN A 140 ? 0.69792 0.83282 0.91637 -0.06152 -0.04774 0.06759  133 GLN A OE1   
1102 N  NE2   . GLN A 140 ? 0.70041 0.86233 0.94751 -0.05323 -0.02729 0.07678  133 GLN A NE2   
1103 N  N     . ALA A 141 ? 0.37778 0.47036 0.53308 -0.04073 -0.01690 0.04158  134 ALA A N     
1104 C  CA    . ALA A 141 ? 0.35530 0.45116 0.50949 -0.03351 -0.00449 0.04043  134 ALA A CA    
1105 C  C     . ALA A 141 ? 0.37812 0.47292 0.52706 -0.02410 0.00002  0.03388  134 ALA A C     
1106 O  O     . ALA A 141 ? 0.35330 0.45565 0.50829 -0.01788 0.00978  0.03494  134 ALA A O     
1107 C  CB    . ALA A 141 ? 0.38460 0.46672 0.52158 -0.03484 -0.00281 0.03752  134 ALA A CB    
1108 N  N     . LEU A 142 ? 0.33129 0.41594 0.46838 -0.02295 -0.00657 0.02735  135 LEU A N     
1109 C  CA    . LEU A 142 ? 0.27738 0.36151 0.41081 -0.01520 -0.00319 0.02193  135 LEU A CA    
1110 C  C     . LEU A 142 ? 0.31805 0.41583 0.46912 -0.01291 -0.00202 0.02625  135 LEU A C     
1111 O  O     . LEU A 142 ? 0.25741 0.35785 0.40970 -0.00580 0.00487  0.02425  135 LEU A O     
1112 C  CB    . LEU A 142 ? 0.33760 0.40905 0.45599 -0.01479 -0.01004 0.01515  135 LEU A CB    
1113 C  CG    . LEU A 142 ? 0.39096 0.44901 0.49207 -0.01474 -0.01027 0.01067  135 LEU A CG    
1114 C  CD1   . LEU A 142 ? 0.34713 0.39518 0.43578 -0.01202 -0.01442 0.00447  135 LEU A CD1   
1115 C  CD2   . LEU A 142 ? 0.35747 0.41572 0.45449 -0.01051 -0.00154 0.00962  135 LEU A CD2   
1116 N  N     . ARG A 143 ? 0.27853 0.38430 0.44295 -0.01895 -0.00910 0.03252  136 ARG A N     
1117 C  CA    . ARG A 143 ? 0.35613 0.47678 0.53992 -0.01662 -0.00820 0.03823  136 ARG A CA    
1118 C  C     . ARG A 143 ? 0.33612 0.46989 0.53477 -0.01244 0.00342  0.04421  136 ARG A C     
1119 O  O     . ARG A 143 ? 0.36065 0.50183 0.56814 -0.00509 0.01010  0.04545  136 ARG A O     
1120 C  CB    . ARG A 143 ? 0.35027 0.47649 0.54488 -0.02513 -0.01996 0.04446  136 ARG A CB    
1121 C  CG    . ARG A 143 ? 0.32471 0.43805 0.50480 -0.02746 -0.03043 0.03897  136 ARG A CG    
1122 C  CD    . ARG A 143 ? 0.33025 0.44939 0.52115 -0.03525 -0.04229 0.04569  136 ARG A CD    
1123 N  NE    . ARG A 143 ? 0.36179 0.47951 0.55431 -0.04555 -0.04893 0.05058  136 ARG A NE    
1124 C  CZ    . ARG A 143 ? 0.41181 0.51172 0.58523 -0.05197 -0.05712 0.04659  136 ARG A CZ    
1125 N  NH1   . ARG A 143 ? 0.29044 0.37354 0.44243 -0.04860 -0.05886 0.03789  136 ARG A NH1   
1126 N  NH2   . ARG A 143 ? 0.39294 0.49131 0.56861 -0.06182 -0.06313 0.05178  136 ARG A NH2   
1127 N  N     . ILE A 144 ? 0.31342 0.44918 0.51416 -0.01672 0.00656  0.04824  137 ILE A N     
1128 C  CA    . ILE A 144 ? 0.34361 0.49016 0.55580 -0.01235 0.01933  0.05387  137 ILE A CA    
1129 C  C     . ILE A 144 ? 0.31534 0.45322 0.51334 -0.00245 0.03003  0.04689  137 ILE A C     
1130 O  O     . ILE A 144 ? 0.33470 0.48018 0.54166 0.00496  0.04032  0.04976  137 ILE A O     
1131 C  CB    . ILE A 144 ? 0.37734 0.52394 0.58949 -0.01926 0.02062  0.05840  137 ILE A CB    
1132 C  CG1   . ILE A 144 ? 0.46179 0.62156 0.69437 -0.02903 0.01222  0.06843  137 ILE A CG1   
1133 C  CG2   . ILE A 144 ? 0.37958 0.53020 0.59319 -0.01329 0.03579  0.06107  137 ILE A CG2   
1134 C  CD1   . ILE A 144 ? 0.51021 0.66041 0.73351 -0.03939 0.00491  0.06911  137 ILE A CD1   
1135 N  N     . LEU A 145 ? 0.25747 0.37870 0.43282 -0.00222 0.02766  0.03801  138 LEU A N     
1136 C  CA    . LEU A 145 ? 0.28272 0.39385 0.44251 0.00554  0.03542  0.03113  138 LEU A CA    
1137 C  C     . LEU A 145 ? 0.29025 0.40285 0.45351 0.01177  0.03600  0.02869  138 LEU A C     
1138 O  O     . LEU A 145 ? 0.28976 0.40137 0.45141 0.01916  0.04574  0.02792  138 LEU A O     
1139 C  CB    . LEU A 145 ? 0.35003 0.44526 0.48803 0.00334  0.03028  0.02345  138 LEU A CB    
1140 C  CG    . LEU A 145 ? 0.39140 0.47416 0.51045 0.00877  0.03530  0.01635  138 LEU A CG    
1141 C  CD1   . LEU A 145 ? 0.26896 0.35148 0.38519 0.01294  0.04745  0.01864  138 LEU A CD1   
1142 C  CD2   . LEU A 145 ? 0.30775 0.37868 0.41054 0.00524  0.02872  0.01152  138 LEU A CD2   
1143 N  N     . ALA A 146 ? 0.24008 0.35332 0.40645 0.00893  0.02582  0.02748  139 ALA A N     
1144 C  CA    . ALA A 146 ? 0.30752 0.42223 0.47782 0.01429  0.02571  0.02601  139 ALA A CA    
1145 C  C     . ALA A 146 ? 0.30466 0.43413 0.49583 0.01883  0.03245  0.03401  139 ALA A C     
1146 O  O     . ALA A 146 ? 0.30573 0.43409 0.49732 0.02652  0.03871  0.03281  139 ALA A O     
1147 C  CB    . ALA A 146 ? 0.28434 0.39720 0.45407 0.00974  0.01350  0.02443  139 ALA A CB    
1148 N  N     . GLU A 147 ? 0.26543 0.40880 0.47463 0.01420  0.03124  0.04279  140 GLU A N     
1149 C  CA    . GLU A 147 ? 0.35960 0.52002 0.59247 0.01860  0.03748  0.05210  140 GLU A CA    
1150 C  C     . GLU A 147 ? 0.35827 0.51837 0.58960 0.02716  0.05367  0.05296  140 GLU A C     
1151 O  O     . GLU A 147 ? 0.32703 0.49587 0.57198 0.03501  0.06177  0.05786  140 GLU A O     
1152 C  CB    . GLU A 147 ? 0.27197 0.44843 0.52586 0.01021  0.03112  0.06225  140 GLU A CB    
1153 C  CG    . GLU A 147 ? 0.50996 0.68962 0.77046 0.00369  0.01587  0.06405  140 GLU A CG    
1154 C  CD    . GLU A 147 ? 0.62583 0.81275 0.89642 -0.00810 0.00579  0.07090  140 GLU A CD    
1155 O  OE1   . GLU A 147 ? 0.64116 0.82340 0.90770 -0.01515 -0.00787 0.06990  140 GLU A OE1   
1156 O  OE2   . GLU A 147 ? 0.57258 0.76872 0.85400 -0.01059 0.01154  0.07744  140 GLU A OE2   
1157 N  N     . ALA A 148 ? 0.27132 0.42049 0.48537 0.02619  0.05877  0.04857  141 ALA A N     
1158 C  CA    . ALA A 148 ? 0.26267 0.40614 0.46813 0.03433  0.07392  0.04764  141 ALA A CA    
1159 C  C     . ALA A 148 ? 0.31751 0.44517 0.50461 0.04197  0.07757  0.03901  141 ALA A C     
1160 O  O     . ALA A 148 ? 0.33268 0.45183 0.50870 0.04900  0.08983  0.03731  141 ALA A O     
1161 C  CB    . ALA A 148 ? 0.30045 0.43553 0.49088 0.03009  0.07678  0.04571  141 ALA A CB    
1162 N  N     . GLY A 149 ? 0.28106 0.40318 0.46310 0.04040  0.06744  0.03366  142 GLY A N     
1163 C  CA    . GLY A 149 ? 0.26599 0.37380 0.43245 0.04653  0.06976  0.02634  142 GLY A CA    
1164 C  C     . GLY A 149 ? 0.31393 0.40470 0.45619 0.04282  0.06374  0.01676  142 GLY A C     
1165 O  O     . GLY A 149 ? 0.28667 0.36534 0.41593 0.04646  0.06432  0.01088  142 GLY A O     
1166 N  N     . ALA A 150 ? 0.26852 0.35785 0.40473 0.03576  0.05798  0.01551  147 ALA A N     
1167 C  CA    . ALA A 150 ? 0.25311 0.32853 0.36927 0.03256  0.05173  0.00761  147 ALA A CA    
1168 C  C     . ALA A 150 ? 0.32828 0.40311 0.44577 0.03067  0.04193  0.00452  147 ALA A C     
1169 O  O     . ALA A 150 ? 0.33026 0.41494 0.46162 0.02762  0.03563  0.00834  147 ALA A O     
1170 C  CB    . ALA A 150 ? 0.31299 0.38784 0.42449 0.02611  0.04777  0.00811  147 ALA A CB    
1171 N  N     . THR A 151 ? 0.26725 0.33005 0.36966 0.03199  0.04037  -0.00201 148 THR A N     
1172 C  CA    . THR A 151 ? 0.29622 0.35748 0.39824 0.03034  0.03215  -0.00493 148 THR A CA    
1173 C  C     . THR A 151 ? 0.36685 0.42401 0.45990 0.02493  0.02474  -0.00816 148 THR A C     
1174 O  O     . THR A 151 ? 0.25958 0.30778 0.33867 0.02446  0.02530  -0.01206 148 THR A O     
1175 C  CB    . THR A 151 ? 0.35270 0.40393 0.44527 0.03457  0.03479  -0.00919 148 THR A CB    
1176 O  OG1   . THR A 151 ? 0.29527 0.34933 0.39604 0.04075  0.04255  -0.00579 148 THR A OG1   
1177 C  CG2   . THR A 151 ? 0.31449 0.36480 0.40732 0.03254  0.02682  -0.01143 148 THR A CG2   
1178 N  N     . MET A 152 ? 0.27370 0.33663 0.37411 0.02103  0.01772  -0.00619 149 MET A N     
1179 C  CA    . MET A 152 ? 0.28038 0.33917 0.37305 0.01686  0.01164  -0.00843 149 MET A CA    
1180 C  C     . MET A 152 ? 0.29702 0.35267 0.38631 0.01646  0.00582  -0.01148 149 MET A C     
1181 O  O     . MET A 152 ? 0.29841 0.35796 0.39502 0.01635  0.00283  -0.00974 149 MET A O     
1182 C  CB    . MET A 152 ? 0.33717 0.40142 0.43719 0.01251  0.00851  -0.00408 149 MET A CB    
1183 C  CG    . MET A 152 ? 0.48914 0.55629 0.59164 0.01240  0.01484  -0.00070 149 MET A CG    
1184 S  SD    . MET A 152 ? 0.64211 0.70993 0.74583 0.00579  0.00996  0.00268  149 MET A SD    
1185 C  CE    . MET A 152 ? 0.60251 0.65813 0.68755 0.00617  0.00986  -0.00248 149 MET A CE    
1186 N  N     . LYS A 153 ? 0.25627 0.30527 0.33481 0.01626  0.00430  -0.01539 150 LYS A N     
1187 C  CA    . LYS A 153 ? 0.25713 0.30373 0.33267 0.01611  -0.00001 -0.01772 150 LYS A CA    
1188 C  C     . LYS A 153 ? 0.29722 0.34011 0.36542 0.01458  -0.00311 -0.01923 150 LYS A C     
1189 O  O     . LYS A 153 ? 0.31386 0.35473 0.37764 0.01391  -0.00201 -0.01915 150 LYS A O     
1190 C  CB    . LYS A 153 ? 0.27000 0.31310 0.34190 0.01830  0.00200  -0.02026 150 LYS A CB    
1191 C  CG    . LYS A 153 ? 0.34593 0.39063 0.42375 0.02116  0.00601  -0.01887 150 LYS A CG    
1192 C  CD    . LYS A 153 ? 0.52110 0.55851 0.59167 0.02298  0.00834  -0.02184 150 LYS A CD    
1193 C  CE    . LYS A 153 ? 0.60314 0.64084 0.67950 0.02616  0.01049  -0.02054 150 LYS A CE    
1194 N  NZ    . LYS A 153 ? 0.64889 0.69367 0.73497 0.02541  0.00627  -0.01758 150 LYS A NZ    
1195 N  N     . ILE A 154 ? 0.24650 0.28820 0.31322 0.01456  -0.00649 -0.02018 151 ILE A N     
1196 C  CA    . ILE A 154 ? 0.24801 0.28662 0.30882 0.01464  -0.00850 -0.02120 151 ILE A CA    
1197 C  C     . ILE A 154 ? 0.27211 0.31053 0.33037 0.01559  -0.00800 -0.02284 151 ILE A C     
1198 O  O     . ILE A 154 ? 0.27841 0.31764 0.33857 0.01595  -0.00760 -0.02356 151 ILE A O     
1199 C  CB    . ILE A 154 ? 0.26245 0.29901 0.32204 0.01476  -0.01127 -0.02095 151 ILE A CB    
1200 C  CG1   . ILE A 154 ? 0.26159 0.29681 0.32242 0.01239  -0.01346 -0.01909 151 ILE A CG1   
1201 C  CG2   . ILE A 154 ? 0.21908 0.25253 0.27321 0.01638  -0.01185 -0.02150 151 ILE A CG2   
1202 C  CD1   . ILE A 154 ? 0.22993 0.26306 0.28867 0.01066  -0.01350 -0.01799 151 ILE A CD1   
1203 N  N     . MET A 155 ? 0.26294 0.29995 0.31685 0.01553  -0.00869 -0.02295 152 MET A N     
1204 C  CA    . MET A 155 ? 0.24890 0.28638 0.30106 0.01537  -0.00995 -0.02356 152 MET A CA    
1205 C  C     . MET A 155 ? 0.27816 0.31864 0.33405 0.01639  -0.01115 -0.02296 152 MET A C     
1206 O  O     . MET A 155 ? 0.25437 0.29485 0.31047 0.01813  -0.01138 -0.02199 152 MET A O     
1207 C  CB    . MET A 155 ? 0.23772 0.27387 0.28537 0.01515  -0.01159 -0.02270 152 MET A CB    
1208 C  CG    . MET A 155 ? 0.24881 0.28077 0.29015 0.01383  -0.01014 -0.02324 152 MET A CG    
1209 S  SD    . MET A 155 ? 0.25330 0.28281 0.28786 0.01328  -0.01326 -0.02170 152 MET A SD    
1210 C  CE    . MET A 155 ? 0.23378 0.26428 0.26706 0.01128  -0.01751 -0.02181 152 MET A CE    
1211 N  N     . ASN A 156 ? 0.25560 0.29738 0.31330 0.01538  -0.01146 -0.02337 153 ASN A N     
1212 C  CA    . ASN A 156 ? 0.24819 0.29365 0.30987 0.01593  -0.01201 -0.02202 153 ASN A CA    
1213 C  C     . ASN A 156 ? 0.20402 0.25268 0.26717 0.01407  -0.01454 -0.02063 153 ASN A C     
1214 O  O     . ASN A 156 ? 0.22018 0.26658 0.27929 0.01221  -0.01647 -0.02115 153 ASN A O     
1215 C  CB    . ASN A 156 ? 0.22431 0.26892 0.28777 0.01549  -0.01088 -0.02261 153 ASN A CB    
1216 C  CG    . ASN A 156 ? 0.26986 0.31702 0.33598 0.01690  -0.01008 -0.02092 153 ASN A CG    
1217 O  OD1   . ASN A 156 ? 0.25544 0.30602 0.32336 0.01838  -0.00980 -0.01906 153 ASN A OD1   
1218 N  ND2   . ASN A 156 ? 0.28009 0.32535 0.34628 0.01689  -0.00927 -0.02112 153 ASN A ND2   
1219 N  N     . TYR A 157 ? 0.20485 0.25878 0.27369 0.01423  -0.01471 -0.01834 154 TYR A N     
1220 C  CA    . TYR A 157 ? 0.22963 0.28890 0.30283 0.01169  -0.01794 -0.01563 154 TYR A CA    
1221 C  C     . TYR A 157 ? 0.28680 0.34094 0.35447 0.00686  -0.02146 -0.01733 154 TYR A C     
1222 O  O     . TYR A 157 ? 0.20355 0.25821 0.26946 0.00463  -0.02547 -0.01611 154 TYR A O     
1223 C  CB    . TYR A 157 ? 0.22473 0.29010 0.30553 0.01158  -0.01664 -0.01279 154 TYR A CB    
1224 C  CG    . TYR A 157 ? 0.27832 0.35117 0.36643 0.00786  -0.02050 -0.00878 154 TYR A CG    
1225 C  CD1   . TYR A 157 ? 0.24201 0.32446 0.33872 0.01018  -0.02086 -0.00403 154 TYR A CD1   
1226 C  CD2   . TYR A 157 ? 0.29344 0.36329 0.37990 0.00188  -0.02412 -0.00928 154 TYR A CD2   
1227 C  CE1   . TYR A 157 ? 0.29704 0.38847 0.40296 0.00620  -0.02525 0.00087  154 TYR A CE1   
1228 C  CE2   . TYR A 157 ? 0.28426 0.36074 0.37752 -0.00298 -0.02907 -0.00505 154 TYR A CE2   
1229 C  CZ    . TYR A 157 ? 0.32948 0.41796 0.43361 -0.00104 -0.02990 0.00037  154 TYR A CZ    
1230 O  OH    . TYR A 157 ? 0.40337 0.50040 0.51660 -0.00646 -0.03564 0.00573  154 TYR A OH    
1231 N  N     . ASN A 158 ? 0.30196 0.34967 0.36547 0.00537  -0.02013 -0.02001 155 ASN A N     
1232 C  CA    . ASN A 158 ? 0.29311 0.33251 0.34830 0.00132  -0.02265 -0.02205 155 ASN A CA    
1233 C  C     . ASN A 158 ? 0.28054 0.31439 0.32699 0.00178  -0.02290 -0.02380 155 ASN A C     
1234 O  O     . ASN A 158 ? 0.27952 0.30771 0.31814 -0.00190 -0.02672 -0.02422 155 ASN A O     
1235 C  CB    . ASN A 158 ? 0.26080 0.29268 0.31226 0.00143  -0.01978 -0.02461 155 ASN A CB    
1236 C  CG    . ASN A 158 ? 0.38034 0.41479 0.43744 -0.00070 -0.02056 -0.02275 155 ASN A CG    
1237 O  OD1   . ASN A 158 ? 0.35406 0.39573 0.41763 -0.00333 -0.02353 -0.01941 155 ASN A OD1   
1238 N  ND2   . ASN A 158 ? 0.37507 0.40420 0.43056 0.00053  -0.01774 -0.02420 155 ASN A ND2   
1239 N  N     . GLU A 159 ? 0.27262 0.30713 0.31929 0.00571  -0.01921 -0.02455 156 GLU A N     
1240 C  CA    . GLU A 159 ? 0.27034 0.29945 0.30868 0.00605  -0.01855 -0.02573 156 GLU A CA    
1241 C  C     . GLU A 159 ? 0.28947 0.32213 0.32779 0.00536  -0.02261 -0.02324 156 GLU A C     
1242 O  O     . GLU A 159 ? 0.27282 0.29953 0.30178 0.00333  -0.02480 -0.02365 156 GLU A O     
1243 C  CB    . GLU A 159 ? 0.28817 0.31726 0.32789 0.00953  -0.01358 -0.02651 156 GLU A CB    
1244 C  CG    . GLU A 159 ? 0.32459 0.34927 0.36324 0.01060  -0.00948 -0.02839 156 GLU A CG    
1245 C  CD    . GLU A 159 ? 0.31256 0.34109 0.35886 0.01129  -0.00938 -0.02789 156 GLU A CD    
1246 O  OE1   . GLU A 159 ? 0.28367 0.31839 0.33625 0.01224  -0.01038 -0.02627 156 GLU A OE1   
1247 O  OE2   . GLU A 159 ? 0.31039 0.33430 0.35496 0.01115  -0.00803 -0.02906 156 GLU A OE2   
1248 N  N     . PHE A 160 ? 0.26585 0.30716 0.31350 0.00751  -0.02334 -0.02042 157 PHE A N     
1249 C  CA    . PHE A 160 ? 0.26323 0.30890 0.31277 0.00754  -0.02740 -0.01707 157 PHE A CA    
1250 C  C     . PHE A 160 ? 0.25211 0.29881 0.30113 0.00260  -0.03358 -0.01525 157 PHE A C     
1251 O  O     . PHE A 160 ? 0.26006 0.30488 0.30390 0.00056  -0.03825 -0.01370 157 PHE A O     
1252 C  CB    . PHE A 160 ? 0.21233 0.26633 0.27204 0.01178  -0.02586 -0.01408 157 PHE A CB    
1253 C  CG    . PHE A 160 ? 0.22269 0.27339 0.28037 0.01572  -0.02156 -0.01548 157 PHE A CG    
1254 C  CD1   . PHE A 160 ? 0.22211 0.26833 0.27390 0.01671  -0.02172 -0.01544 157 PHE A CD1   
1255 C  CD2   . PHE A 160 ? 0.27363 0.32465 0.33424 0.01773  -0.01796 -0.01655 157 PHE A CD2   
1256 C  CE1   . PHE A 160 ? 0.19401 0.23630 0.24364 0.01912  -0.01861 -0.01636 157 PHE A CE1   
1257 C  CE2   . PHE A 160 ? 0.22175 0.26841 0.27928 0.02014  -0.01542 -0.01760 157 PHE A CE2   
1258 C  CZ    . PHE A 160 ? 0.21587 0.25824 0.26830 0.02055  -0.01585 -0.01749 157 PHE A CZ    
1259 N  N     . GLN A 161 ? 0.22771 0.27669 0.28144 -0.00003 -0.03435 -0.01505 158 GLN A N     
1260 C  CA    . GLN A 161 ? 0.24107 0.29026 0.29423 -0.00619 -0.04124 -0.01295 158 GLN A CA    
1261 C  C     . GLN A 161 ? 0.27391 0.30882 0.31000 -0.01023 -0.04391 -0.01645 158 GLN A C     
1262 O  O     . GLN A 161 ? 0.27967 0.31223 0.31028 -0.01467 -0.05090 -0.01455 158 GLN A O     
1263 C  CB    . GLN A 161 ? 0.27069 0.32320 0.33097 -0.00872 -0.04095 -0.01218 158 GLN A CB    
1264 C  CG    . GLN A 161 ? 0.30359 0.35487 0.36276 -0.01659 -0.04876 -0.00991 158 GLN A CG    
1265 C  CD    . GLN A 161 ? 0.39818 0.45269 0.46488 -0.01935 -0.04811 -0.00857 158 GLN A CD    
1266 O  OE1   . GLN A 161 ? 0.44627 0.51300 0.52648 -0.02177 -0.05110 -0.00287 158 GLN A OE1   
1267 N  NE2   . GLN A 161 ? 0.33444 0.37884 0.39361 -0.01848 -0.04359 -0.01314 158 GLN A NE2   
1268 N  N     . ASP A 162 ? 0.28418 0.30896 0.31121 -0.00854 -0.03829 -0.02120 159 ASP A N     
1269 C  CA    . ASP A 162 ? 0.31873 0.32805 0.32765 -0.01097 -0.03865 -0.02472 159 ASP A CA    
1270 C  C     . ASP A 162 ? 0.37951 0.38608 0.38046 -0.01004 -0.03971 -0.02410 159 ASP A C     
1271 O  O     . ASP A 162 ? 0.36104 0.35737 0.34766 -0.01412 -0.04440 -0.02461 159 ASP A O     
1272 C  CB    . ASP A 162 ? 0.33977 0.34128 0.34386 -0.00744 -0.03070 -0.02883 159 ASP A CB    
1273 C  CG    . ASP A 162 ? 0.46324 0.44700 0.44792 -0.00923 -0.02957 -0.03251 159 ASP A CG    
1274 O  OD1   . ASP A 162 ? 0.42774 0.40271 0.40308 -0.01495 -0.03556 -0.03297 159 ASP A OD1   
1275 O  OD2   . ASP A 162 ? 0.44755 0.42561 0.42576 -0.00504 -0.02266 -0.03460 159 ASP A OD2   
1276 N  N     . CYS A 163 ? 0.27553 0.28957 0.28400 -0.00507 -0.03575 -0.02290 160 CYS A N     
1277 C  CA    . CYS A 163 ? 0.24175 0.25313 0.24315 -0.00413 -0.03660 -0.02175 160 CYS A CA    
1278 C  C     . CYS A 163 ? 0.26047 0.27625 0.26338 -0.00736 -0.04551 -0.01745 160 CYS A C     
1279 O  O     . CYS A 163 ? 0.33870 0.34669 0.32890 -0.00977 -0.04946 -0.01691 160 CYS A O     
1280 C  CB    . CYS A 163 ? 0.27646 0.29443 0.28636 0.00121  -0.03126 -0.02091 160 CYS A CB    
1281 S  SG    . CYS A 163 ? 0.39612 0.40759 0.39514 0.00251  -0.02972 -0.02019 160 CYS A SG    
1282 N  N     . TRP A 164 ? 0.24924 0.27775 0.26785 -0.00734 -0.04869 -0.01377 161 TRP A N     
1283 C  CA    . TRP A 164 ? 0.24791 0.28357 0.27195 -0.01042 -0.05750 -0.00833 161 TRP A CA    
1284 C  C     . TRP A 164 ? 0.34662 0.37269 0.35806 -0.01839 -0.06542 -0.00881 161 TRP A C     
1285 O  O     . TRP A 164 ? 0.30808 0.33121 0.31226 -0.02170 -0.07292 -0.00605 161 TRP A O     
1286 C  CB    . TRP A 164 ? 0.24668 0.29823 0.29104 -0.00866 -0.05759 -0.00405 161 TRP A CB    
1287 C  CG    . TRP A 164 ? 0.28742 0.34975 0.34203 -0.01182 -0.06636 0.00291  161 TRP A CG    
1288 C  CD1   . TRP A 164 ? 0.30617 0.37093 0.36354 -0.01930 -0.07407 0.00560  161 TRP A CD1   
1289 C  CD2   . TRP A 164 ? 0.32208 0.39502 0.38715 -0.00759 -0.06852 0.00894  161 TRP A CD2   
1290 N  NE1   . TRP A 164 ? 0.30685 0.38500 0.37746 -0.02033 -0.08132 0.01351  161 TRP A NE1   
1291 C  CE2   . TRP A 164 ? 0.30761 0.39102 0.38326 -0.01255 -0.07768 0.01570  161 TRP A CE2   
1292 C  CE3   . TRP A 164 ? 0.25424 0.32821 0.32066 -0.00013 -0.06380 0.00965  161 TRP A CE3   
1293 C  CZ2   . TRP A 164 ? 0.39663 0.49300 0.48569 -0.00937 -0.08174 0.02353  161 TRP A CZ2   
1294 C  CZ3   . TRP A 164 ? 0.26487 0.34922 0.34225 0.00321  -0.06752 0.01669  161 TRP A CZ3   
1295 C  CH2   . TRP A 164 ? 0.27282 0.36906 0.36223 -0.00089 -0.07615 0.02377  161 TRP A CH2   
1296 N  N     . ASN A 165 ? 0.31486 0.33453 0.32229 -0.02181 -0.06441 -0.01213 162 ASN A N     
1297 C  CA    . ASN A 165 ? 0.32715 0.33456 0.32020 -0.03007 -0.07231 -0.01297 162 ASN A CA    
1298 C  C     . ASN A 165 ? 0.42883 0.41747 0.39718 -0.03117 -0.07237 -0.01671 162 ASN A C     
1299 O  O     . ASN A 165 ? 0.40466 0.38435 0.35978 -0.03772 -0.08158 -0.01542 162 ASN A O     
1300 C  CB    . ASN A 165 ? 0.32052 0.32195 0.31227 -0.03264 -0.06991 -0.01626 162 ASN A CB    
1301 C  CG    . ASN A 165 ? 0.38410 0.40235 0.39777 -0.03355 -0.07133 -0.01176 162 ASN A CG    
1302 O  OD1   . ASN A 165 ? 0.33006 0.36360 0.35886 -0.03423 -0.07638 -0.00544 162 ASN A OD1   
1303 N  ND2   . ASN A 165 ? 0.38107 0.39660 0.39673 -0.03314 -0.06639 -0.01447 162 ASN A ND2   
1304 N  N     . LYS A 166 ? 0.37896 0.36124 0.34045 -0.02515 -0.06231 -0.02088 163 LYS A N     
1305 C  CA    . LYS A 166 ? 0.37154 0.33488 0.30878 -0.02545 -0.05972 -0.02466 163 LYS A CA    
1306 C  C     . LYS A 166 ? 0.43526 0.39905 0.36736 -0.02377 -0.06108 -0.02207 163 LYS A C     
1307 O  O     . LYS A 166 ? 0.42286 0.37161 0.33368 -0.02718 -0.06470 -0.02287 163 LYS A O     
1308 C  CB    . LYS A 166 ? 0.39633 0.35295 0.32954 -0.01982 -0.04746 -0.02955 163 LYS A CB    
1309 C  CG    . LYS A 166 ? 0.43210 0.38318 0.36508 -0.02106 -0.04546 -0.03263 163 LYS A CG    
1310 C  CD    . LYS A 166 ? 0.53121 0.48012 0.46560 -0.01423 -0.03339 -0.03589 163 LYS A CD    
1311 C  CE    . LYS A 166 ? 0.51933 0.45526 0.44505 -0.01499 -0.03073 -0.03959 163 LYS A CE    
1312 N  NZ    . LYS A 166 ? 0.46636 0.40695 0.40198 -0.00794 -0.02031 -0.04086 163 LYS A NZ    
1313 N  N     . PHE A 167 ? 0.28778 0.26643 0.23682 -0.01857 -0.05807 -0.01908 164 PHE A N     
1314 C  CA    . PHE A 167 ? 0.34517 0.32196 0.28820 -0.01586 -0.05672 -0.01732 164 PHE A CA    
1315 C  C     . PHE A 167 ? 0.37205 0.36085 0.32664 -0.01573 -0.06452 -0.01106 164 PHE A C     
1316 O  O     . PHE A 167 ? 0.39385 0.38134 0.34450 -0.01315 -0.06369 -0.00903 164 PHE A O     
1317 C  CB    . PHE A 167 ? 0.32210 0.30195 0.27125 -0.00951 -0.04546 -0.01925 164 PHE A CB    
1318 C  CG    . PHE A 167 ? 0.36196 0.33053 0.30010 -0.00840 -0.03677 -0.02424 164 PHE A CG    
1319 C  CD1   . PHE A 167 ? 0.43282 0.38584 0.34980 -0.00885 -0.03322 -0.02608 164 PHE A CD1   
1320 C  CD2   . PHE A 167 ? 0.35593 0.32918 0.30466 -0.00635 -0.03169 -0.02658 164 PHE A CD2   
1321 C  CE1   . PHE A 167 ? 0.35236 0.29541 0.26010 -0.00658 -0.02392 -0.02999 164 PHE A CE1   
1322 C  CE2   . PHE A 167 ? 0.39053 0.35414 0.33063 -0.00436 -0.02343 -0.03034 164 PHE A CE2   
1323 C  CZ    . PHE A 167 ? 0.35607 0.30500 0.27636 -0.00411 -0.01912 -0.03195 164 PHE A CZ    
1324 N  N     . VAL A 168 ? 0.34751 0.34806 0.31669 -0.01817 -0.07166 -0.00735 165 VAL A N     
1325 C  CA    . VAL A 168 ? 0.39696 0.41187 0.38164 -0.01629 -0.07747 -0.00049 165 VAL A CA    
1326 C  C     . VAL A 168 ? 0.41224 0.42914 0.39639 -0.02347 -0.09038 0.00425  165 VAL A C     
1327 O  O     . VAL A 168 ? 0.36965 0.38362 0.35156 -0.02950 -0.09431 0.00287  165 VAL A O     
1328 C  CB    . VAL A 168 ? 0.31211 0.34331 0.32003 -0.01080 -0.07229 0.00121  165 VAL A CB    
1329 C  CG1   . VAL A 168 ? 0.27383 0.31927 0.29769 -0.00768 -0.07716 0.00877  165 VAL A CG1   
1330 C  CG2   . VAL A 168 ? 0.28748 0.31556 0.29460 -0.00485 -0.06133 -0.00301 165 VAL A CG2   
1331 N  N     . ASP A 169 ? 0.37619 0.39767 0.36237 -0.02316 -0.09758 0.01032  166 ASP A N     
1332 C  CA    . ASP A 169 ? 0.42703 0.45297 0.41541 -0.03005 -0.11150 0.01668  166 ASP A CA    
1333 C  C     . ASP A 169 ? 0.48157 0.52978 0.49876 -0.02895 -0.11379 0.02289  166 ASP A C     
1334 O  O     . ASP A 169 ? 0.47231 0.53548 0.50627 -0.02597 -0.11838 0.03087  166 ASP A O     
1335 C  CB    . ASP A 169 ? 0.43141 0.45448 0.41207 -0.02919 -0.11784 0.02150  166 ASP A CB    
1336 C  CG    . ASP A 169 ? 0.60036 0.62357 0.57717 -0.03786 -0.13383 0.02766  166 ASP A CG    
1337 O  OD1   . ASP A 169 ? 0.59263 0.61118 0.56417 -0.04618 -0.13998 0.02626  166 ASP A OD1   
1338 O  OD2   . ASP A 169 ? 0.60711 0.63449 0.58582 -0.03657 -0.14080 0.03427  166 ASP A OD2   
1339 N  N     . GLY A 170 ? 0.39148 0.44162 0.41445 -0.03083 -0.10964 0.01947  167 GLY A N     
1340 C  CA    . GLY A 170 ? 0.40372 0.47357 0.45246 -0.03011 -0.10994 0.02480  167 GLY A CA    
1341 C  C     . GLY A 170 ? 0.58719 0.66668 0.64559 -0.03869 -0.12360 0.03265  167 GLY A C     
1342 O  O     . GLY A 170 ? 0.53865 0.63821 0.62205 -0.03733 -0.12427 0.03962  167 GLY A O     
1343 N  N     . ARG A 171 ? 0.59008 0.65532 0.62880 -0.04773 -0.13443 0.03200  168 ARG A N     
1344 C  CA    . ARG A 171 ? 0.69170 0.76440 0.73731 -0.05758 -0.14999 0.04008  168 ARG A CA    
1345 C  C     . ARG A 171 ? 0.65165 0.73445 0.71318 -0.06314 -0.15104 0.04221  168 ARG A C     
1346 O  O     . ARG A 171 ? 0.68863 0.78761 0.77031 -0.06442 -0.15350 0.05032  168 ARG A O     
1347 C  CB    . ARG A 171 ? 0.56889 0.65996 0.63361 -0.05296 -0.15460 0.05026  168 ARG A CB    
1348 C  CG    . ARG A 171 ? 0.69542 0.77322 0.73993 -0.05317 -0.16060 0.05028  168 ARG A CG    
1349 C  CD    . ARG A 171 ? 0.82189 0.91567 0.88433 -0.04436 -0.15994 0.05847  168 ARG A CD    
1350 N  NE    . ARG A 171 ? 0.93034 1.01066 0.97303 -0.04197 -0.16276 0.05745  168 ARG A NE    
1351 C  CZ    . ARG A 171 ? 0.91867 0.97966 0.93474 -0.04926 -0.17050 0.05522  168 ARG A CZ    
1352 N  NH1   . ARG A 171 ? 0.90306 0.95521 0.90887 -0.05968 -0.17738 0.05423  168 ARG A NH1   
1353 N  NH2   . ARG A 171 ? 0.84233 0.89133 0.84070 -0.04591 -0.17106 0.05434  168 ARG A NH2   
1354 N  N     . GLY A 172 ? 0.59619 0.66616 0.64643 -0.06422 -0.14372 0.03383  169 GLY A N     
1355 C  CA    . GLY A 172 ? 0.56962 0.64594 0.63168 -0.06995 -0.14454 0.03519  169 GLY A CA    
1356 C  C     . GLY A 172 ? 0.66555 0.76387 0.75582 -0.06201 -0.13442 0.03891  169 GLY A C     
1357 O  O     . GLY A 172 ? 0.54246 0.64407 0.64057 -0.06552 -0.13225 0.03883  169 GLY A O     
1358 N  N     . LYS A 173 ? 0.56084 0.67259 0.66495 -0.05140 -0.12796 0.04221  170 LYS A N     
1359 C  CA    . LYS A 173 ? 0.50220 0.63125 0.62893 -0.04293 -0.11702 0.04494  170 LYS A CA    
1360 C  C     . LYS A 173 ? 0.42702 0.54321 0.54180 -0.03771 -0.10425 0.03493  170 LYS A C     
1361 O  O     . LYS A 173 ? 0.42440 0.52356 0.51869 -0.03539 -0.10084 0.02732  170 LYS A O     
1362 C  CB    . LYS A 173 ? 0.46805 0.61144 0.60960 -0.03265 -0.11362 0.05093  170 LYS A CB    
1363 C  CG    . LYS A 173 ? 0.56395 0.72035 0.71864 -0.03545 -0.12269 0.06102  170 LYS A CG    
1364 C  CD    . LYS A 173 ? 0.65797 0.83034 0.83152 -0.02344 -0.11547 0.06750  170 LYS A CD    
1365 C  CE    . LYS A 173 ? 0.71373 0.90309 0.90825 -0.02438 -0.11578 0.07679  170 LYS A CE    
1366 N  NZ    . LYS A 173 ? 0.73774 0.94174 0.95112 -0.01172 -0.10445 0.08173  170 LYS A NZ    
1367 N  N     . PRO A 174 ? 0.42092 0.54521 0.54835 -0.03589 -0.09711 0.03534  171 PRO A N     
1368 C  CA    . PRO A 174 ? 0.38677 0.49950 0.50366 -0.03127 -0.08610 0.02667  171 PRO A CA    
1369 C  C     . PRO A 174 ? 0.40304 0.51749 0.52136 -0.01969 -0.07593 0.02453  171 PRO A C     
1370 O  O     . PRO A 174 ? 0.32503 0.45194 0.45633 -0.01377 -0.07502 0.03038  171 PRO A O     
1371 C  CB    . PRO A 174 ? 0.45310 0.57525 0.58419 -0.03371 -0.08318 0.02955  171 PRO A CB    
1372 C  CG    . PRO A 174 ? 0.52450 0.66825 0.67914 -0.03623 -0.08935 0.04095  171 PRO A CG    
1373 C  CD    . PRO A 174 ? 0.39523 0.54183 0.54936 -0.03611 -0.09743 0.04489  171 PRO A CD    
1374 N  N     . PHE A 175 ? 0.33276 0.43363 0.43713 -0.01661 -0.06850 0.01631  172 PHE A N     
1375 C  CA    . PHE A 175 ? 0.35165 0.45212 0.45603 -0.00701 -0.05913 0.01379  172 PHE A CA    
1376 C  C     . PHE A 175 ? 0.35272 0.46739 0.47487 -0.00128 -0.05286 0.01846  172 PHE A C     
1377 O  O     . PHE A 175 ? 0.38304 0.50268 0.51261 -0.00403 -0.05144 0.01980  172 PHE A O     
1378 C  CB    . PHE A 175 ? 0.29440 0.38000 0.38370 -0.00614 -0.05312 0.00534  172 PHE A CB    
1379 C  CG    . PHE A 175 ? 0.29881 0.38365 0.38849 0.00213  -0.04429 0.00293  172 PHE A CG    
1380 C  CD1   . PHE A 175 ? 0.26999 0.35240 0.35565 0.00688  -0.04316 0.00294  172 PHE A CD1   
1381 C  CD2   . PHE A 175 ? 0.25306 0.33815 0.34571 0.00454  -0.03780 0.00083  172 PHE A CD2   
1382 C  CE1   . PHE A 175 ? 0.30443 0.38406 0.38879 0.01333  -0.03606 0.00076  172 PHE A CE1   
1383 C  CE2   . PHE A 175 ? 0.26756 0.35016 0.35856 0.01109  -0.03101 -0.00129 172 PHE A CE2   
1384 C  CZ    . PHE A 175 ? 0.25622 0.33579 0.34299 0.01523  -0.03028 -0.00141 172 PHE A CZ    
1385 N  N     . LYS A 176 ? 0.28129 0.40087 0.40872 0.00693  -0.04858 0.02094  173 LYS A N     
1386 C  CA    . LYS A 176 ? 0.30891 0.43930 0.45016 0.01424  -0.04098 0.02517  173 LYS A CA    
1387 C  C     . LYS A 176 ? 0.34535 0.46526 0.47641 0.02167  -0.03236 0.01965  173 LYS A C     
1388 O  O     . LYS A 176 ? 0.31838 0.43249 0.44285 0.02585  -0.03209 0.01862  173 LYS A O     
1389 C  CB    . LYS A 176 ? 0.39604 0.54105 0.55301 0.01828  -0.04338 0.03420  173 LYS A CB    
1390 C  CG    . LYS A 176 ? 0.45328 0.61151 0.62680 0.02551  -0.03527 0.04026  173 LYS A CG    
1391 C  CD    . LYS A 176 ? 0.63907 0.81692 0.83398 0.02548  -0.04021 0.05137  173 LYS A CD    
1392 C  CE    . LYS A 176 ? 0.68156 0.86741 0.88435 0.01365  -0.04959 0.05482  173 LYS A CE    
1393 N  NZ    . LYS A 176 ? 0.73998 0.94188 0.96206 0.01354  -0.04506 0.06182  173 LYS A NZ    
1394 N  N     . PRO A 177 ? 0.28257 0.39888 0.41122 0.02304  -0.02588 0.01635  174 PRO A N     
1395 C  CA    . PRO A 177 ? 0.30114 0.40581 0.41827 0.02846  -0.01953 0.01101  174 PRO A CA    
1396 C  C     . PRO A 177 ? 0.31177 0.41831 0.43220 0.03760  -0.01409 0.01436  174 PRO A C     
1397 O  O     . PRO A 177 ? 0.30951 0.42756 0.44298 0.04158  -0.01121 0.02068  174 PRO A O     
1398 C  CB    . PRO A 177 ? 0.32863 0.43068 0.44397 0.02708  -0.01519 0.00823  174 PRO A CB    
1399 C  CG    . PRO A 177 ? 0.34186 0.45694 0.47134 0.02413  -0.01626 0.01404  174 PRO A CG    
1400 C  CD    . PRO A 177 ? 0.31264 0.43438 0.44806 0.01892  -0.02489 0.01764  174 PRO A CD    
1401 N  N     . TRP A 178 ? 0.29933 0.39398 0.40780 0.04100  -0.01244 0.01048  175 TRP A N     
1402 C  CA    . TRP A 178 ? 0.33735 0.42863 0.44446 0.04988  -0.00677 0.01244  175 TRP A CA    
1403 C  C     . TRP A 178 ? 0.39301 0.47825 0.49491 0.05374  0.00090  0.01023  175 TRP A C     
1404 O  O     . TRP A 178 ? 0.30078 0.38302 0.39864 0.04930  0.00112  0.00655  175 TRP A O     
1405 C  CB    . TRP A 178 ? 0.32066 0.39941 0.41536 0.05108  -0.00841 0.00924  175 TRP A CB    
1406 C  CG    . TRP A 178 ? 0.28100 0.34957 0.36402 0.04507  -0.01036 0.00265  175 TRP A CG    
1407 C  CD1   . TRP A 178 ? 0.25661 0.31538 0.33048 0.04510  -0.00685 -0.00186 175 TRP A CD1   
1408 C  CD2   . TRP A 178 ? 0.26323 0.33075 0.34285 0.03834  -0.01610 0.00049  175 TRP A CD2   
1409 N  NE1   . TRP A 178 ? 0.23528 0.28916 0.30302 0.03903  -0.00998 -0.00605 175 TRP A NE1   
1410 C  CE2   . TRP A 178 ? 0.21033 0.26878 0.28073 0.03529  -0.01486 -0.00491 175 TRP A CE2   
1411 C  CE3   . TRP A 178 ? 0.29335 0.36597 0.37591 0.03465  -0.02220 0.00289  175 TRP A CE3   
1412 C  CZ2   . TRP A 178 ? 0.22659 0.28155 0.29162 0.02979  -0.01797 -0.00780 175 TRP A CZ2   
1413 C  CZ3   . TRP A 178 ? 0.25221 0.31893 0.32634 0.02873  -0.02560 -0.00073 175 TRP A CZ3   
1414 C  CH2   . TRP A 178 ? 0.21672 0.27502 0.28266 0.02686  -0.02275 -0.00594 175 TRP A CH2   
1415 N  N     . ASN A 179 ? 0.37965 0.46129 0.47989 0.06249  0.00730  0.01254  176 ASN A N     
1416 C  CA    . ASN A 179 ? 0.46232 0.53633 0.55514 0.06684  0.01504  0.01091  176 ASN A CA    
1417 C  C     . ASN A 179 ? 0.34178 0.39906 0.41701 0.06320  0.01371  0.00353  176 ASN A C     
1418 O  O     . ASN A 179 ? 0.40659 0.45524 0.47375 0.06126  0.00976  0.00052  176 ASN A O     
1419 C  CB    . ASN A 179 ? 0.50227 0.57314 0.59439 0.07783  0.02273  0.01483  176 ASN A CB    
1420 C  CG    . ASN A 179 ? 0.64029 0.69764 0.71858 0.08283  0.03102  0.01222  176 ASN A CG    
1421 O  OD1   . ASN A 179 ? 0.74757 0.78657 0.80751 0.08231  0.03067  0.00654  176 ASN A OD1   
1422 N  ND2   . ASN A 179 ? 0.61487 0.68094 0.70139 0.08696  0.03817  0.01668  176 ASN A ND2   
1423 N  N     . ASN A 180 ? 0.23998 0.29370 0.31035 0.06166  0.01654  0.00133  177 ASN A N     
1424 C  CA    . ASN A 180 ? 0.28293 0.32200 0.33798 0.05837  0.01521  -0.00448 177 ASN A CA    
1425 C  C     . ASN A 180 ? 0.26822 0.30799 0.32361 0.05033  0.00793  -0.00786 177 ASN A C     
1426 O  O     . ASN A 180 ? 0.28955 0.31854 0.33439 0.04750  0.00579  -0.01175 177 ASN A O     
1427 C  CB    . ASN A 180 ? 0.46492 0.48661 0.50408 0.06350  0.01790  -0.00650 177 ASN A CB    
1428 C  CG    . ASN A 180 ? 0.44177 0.45704 0.47431 0.07155  0.02661  -0.00465 177 ASN A CG    
1429 O  OD1   . ASN A 180 ? 0.41932 0.43703 0.45219 0.07118  0.02991  -0.00416 177 ASN A OD1   
1430 N  ND2   . ASN A 180 ? 0.50245 0.50851 0.52806 0.07918  0.03090  -0.00343 177 ASN A ND2   
1431 N  N     . LEU A 181 ? 0.26080 0.31260 0.32771 0.04642  0.00415  -0.00615 178 LEU A N     
1432 C  CA    . LEU A 181 ? 0.23048 0.28183 0.29642 0.03953  -0.00110 -0.00938 178 LEU A CA    
1433 C  C     . LEU A 181 ? 0.22070 0.26708 0.28160 0.03656  -0.00077 -0.01242 178 LEU A C     
1434 O  O     . LEU A 181 ? 0.25059 0.29077 0.30580 0.03348  -0.00333 -0.01545 178 LEU A O     
1435 C  CB    . LEU A 181 ? 0.17218 0.23491 0.24870 0.03572  -0.00482 -0.00709 178 LEU A CB    
1436 C  CG    . LEU A 181 ? 0.18619 0.24734 0.26039 0.02966  -0.00957 -0.00999 178 LEU A CG    
1437 C  CD1   . LEU A 181 ? 0.23153 0.30040 0.31225 0.02683  -0.01394 -0.00722 178 LEU A CD1   
1438 C  CD2   . LEU A 181 ? 0.23482 0.29399 0.30759 0.02595  -0.00944 -0.01272 178 LEU A CD2   
1439 N  N     . PRO A 182 ? 0.28922 0.33818 0.35224 0.03736  0.00233  -0.01117 179 PRO A N     
1440 C  CA    . PRO A 182 ? 0.28816 0.33178 0.34584 0.03448  0.00180  -0.01364 179 PRO A CA    
1441 C  C     . PRO A 182 ? 0.25639 0.28718 0.30124 0.03577  0.00200  -0.01605 179 PRO A C     
1442 O  O     . PRO A 182 ? 0.27178 0.29831 0.31315 0.03207  -0.00144 -0.01825 179 PRO A O     
1443 C  CB    . PRO A 182 ? 0.30213 0.35094 0.36425 0.03559  0.00561  -0.01085 179 PRO A CB    
1444 C  CG    . PRO A 182 ? 0.27203 0.33273 0.34623 0.03636  0.00612  -0.00686 179 PRO A CG    
1445 C  CD    . PRO A 182 ? 0.28841 0.34690 0.36059 0.04011  0.00597  -0.00667 179 PRO A CD    
1446 N  N     . LYS A 183 ? 0.27558 0.29960 0.31312 0.04102  0.00594  -0.01524 180 LYS A N     
1447 C  CA    . LYS A 183 ? 0.33984 0.34846 0.36208 0.04164  0.00540  -0.01763 180 LYS A CA    
1448 C  C     . LYS A 183 ? 0.32383 0.32823 0.34379 0.03804  0.00023  -0.01957 180 LYS A C     
1449 O  O     . LYS A 183 ? 0.32080 0.31718 0.33342 0.03432  -0.00349 -0.02134 180 LYS A O     
1450 C  CB    . LYS A 183 ? 0.35622 0.35610 0.36923 0.04880  0.01139  -0.01652 180 LYS A CB    
1451 C  CG    . LYS A 183 ? 0.57082 0.56170 0.57244 0.05114  0.01561  -0.01661 180 LYS A CG    
1452 C  CD    . LYS A 183 ? 0.74203 0.71951 0.73002 0.05885  0.02212  -0.01623 180 LYS A CD    
1453 C  CE    . LYS A 183 ? 0.68408 0.64381 0.65165 0.05950  0.02395  -0.01816 180 LYS A CE    
1454 N  NZ    . LYS A 183 ? 0.72415 0.66236 0.67108 0.06396  0.02617  -0.02017 180 LYS A NZ    
1455 N  N     . HIS A 184 ? 0.28122 0.29129 0.30776 0.03870  -0.00034 -0.01864 181 HIS A N     
1456 C  CA    . HIS A 184 ? 0.28473 0.29173 0.30980 0.03497  -0.00456 -0.01989 181 HIS A CA    
1457 C  C     . HIS A 184 ? 0.21863 0.23126 0.24954 0.02925  -0.00801 -0.02087 181 HIS A C     
1458 O  O     . HIS A 184 ? 0.24821 0.25587 0.27565 0.02559  -0.01116 -0.02172 181 HIS A O     
1459 C  CB    . HIS A 184 ? 0.22912 0.24142 0.25972 0.03678  -0.00449 -0.01825 181 HIS A CB    
1460 C  CG    . HIS A 184 ? 0.24488 0.25191 0.27104 0.04335  -0.00095 -0.01652 181 HIS A CG    
1461 N  ND1   . HIS A 184 ? 0.26908 0.28394 0.30301 0.04673  -0.00008 -0.01351 181 HIS A ND1   
1462 C  CD2   . HIS A 184 ? 0.28707 0.28090 0.30114 0.04765  0.00213  -0.01707 181 HIS A CD2   
1463 C  CE1   . HIS A 184 ? 0.30661 0.31474 0.33537 0.05355  0.00392  -0.01188 181 HIS A CE1   
1464 N  NE2   . HIS A 184 ? 0.32504 0.31926 0.34059 0.05442  0.00578  -0.01434 181 HIS A NE2   
1465 N  N     . TYR A 185 ? 0.23863 0.26147 0.27876 0.02844  -0.00740 -0.02030 182 TYR A N     
1466 C  CA    . TYR A 185 ? 0.24340 0.27043 0.28852 0.02432  -0.00954 -0.02111 182 TYR A CA    
1467 C  C     . TYR A 185 ? 0.24610 0.26787 0.28706 0.02246  -0.01129 -0.02162 182 TYR A C     
1468 O  O     . TYR A 185 ? 0.25558 0.27713 0.29811 0.01932  -0.01394 -0.02164 182 TYR A O     
1469 C  CB    . TYR A 185 ? 0.26578 0.30105 0.31844 0.02392  -0.00853 -0.02055 182 TYR A CB    
1470 C  CG    . TYR A 185 ? 0.26442 0.30130 0.32027 0.02097  -0.00974 -0.02141 182 TYR A CG    
1471 C  CD1   . TYR A 185 ? 0.25382 0.29216 0.31198 0.01905  -0.01049 -0.02210 182 TYR A CD1   
1472 C  CD2   . TYR A 185 ? 0.31392 0.34986 0.36964 0.02071  -0.00960 -0.02116 182 TYR A CD2   
1473 C  CE1   . TYR A 185 ? 0.30776 0.34709 0.36905 0.01768  -0.01044 -0.02244 182 TYR A CE1   
1474 C  CE2   . TYR A 185 ? 0.39438 0.43140 0.45346 0.01893  -0.01055 -0.02139 182 TYR A CE2   
1475 C  CZ    . TYR A 185 ? 0.40184 0.44075 0.46417 0.01779  -0.01067 -0.02199 182 TYR A CZ    
1476 O  OH    . TYR A 185 ? 0.49388 0.53358 0.55989 0.01730  -0.01049 -0.02177 182 TYR A OH    
1477 N  N     . THR A 186 ? 0.27815 0.29592 0.31395 0.02432  -0.00989 -0.02141 183 THR A N     
1478 C  CA    . THR A 186 ? 0.29975 0.31209 0.33062 0.02212  -0.01258 -0.02149 183 THR A CA    
1479 C  C     . THR A 186 ? 0.31013 0.31333 0.33312 0.01966  -0.01650 -0.02184 183 THR A C     
1480 O  O     . THR A 186 ? 0.31994 0.32319 0.34475 0.01577  -0.02083 -0.02102 183 THR A O     
1481 C  CB    . THR A 186 ? 0.31679 0.32442 0.34061 0.02471  -0.00989 -0.02108 183 THR A CB    
1482 O  OG1   . THR A 186 ? 0.39852 0.39785 0.41251 0.02860  -0.00675 -0.02139 183 THR A OG1   
1483 C  CG2   . THR A 186 ? 0.37596 0.39313 0.40880 0.02579  -0.00670 -0.01995 183 THR A CG2   
1484 N  N     . LEU A 187 ? 0.26266 0.25793 0.27742 0.02172  -0.01532 -0.02252 184 LEU A N     
1485 C  CA    . LEU A 187 ? 0.26706 0.25164 0.27299 0.01857  -0.01950 -0.02279 184 LEU A CA    
1486 C  C     . LEU A 187 ? 0.36716 0.35928 0.38325 0.01411  -0.02260 -0.02162 184 LEU A C     
1487 O  O     . LEU A 187 ? 0.30663 0.29633 0.32243 0.00915  -0.02762 -0.02038 184 LEU A O     
1488 C  CB    . LEU A 187 ? 0.32649 0.30042 0.32178 0.02247  -0.01679 -0.02366 184 LEU A CB    
1489 C  CG    . LEU A 187 ? 0.44116 0.39780 0.41810 0.02563  -0.01518 -0.02486 184 LEU A CG    
1490 C  CD1   . LEU A 187 ? 0.42804 0.37437 0.39651 0.02934  -0.01286 -0.02532 184 LEU A CD1   
1491 C  CD2   . LEU A 187 ? 0.36712 0.31141 0.33181 0.02037  -0.02121 -0.02540 184 LEU A CD2   
1492 N  N     . LEU A 188 ? 0.27942 0.28046 0.30422 0.01568  -0.01966 -0.02149 185 LEU A N     
1493 C  CA    . LEU A 188 ? 0.22443 0.23193 0.25753 0.01229  -0.02092 -0.02023 185 LEU A CA    
1494 C  C     . LEU A 188 ? 0.21070 0.22685 0.25371 0.01001  -0.02201 -0.01894 185 LEU A C     
1495 O  O     . LEU A 188 ? 0.26621 0.28556 0.31495 0.00637  -0.02423 -0.01678 185 LEU A O     
1496 C  CB    . LEU A 188 ? 0.21835 0.23148 0.25558 0.01476  -0.01750 -0.02053 185 LEU A CB    
1497 C  CG    . LEU A 188 ? 0.26338 0.26918 0.29293 0.01728  -0.01668 -0.02072 185 LEU A CG    
1498 C  CD1   . LEU A 188 ? 0.24914 0.26183 0.28339 0.01998  -0.01421 -0.02047 185 LEU A CD1   
1499 C  CD2   . LEU A 188 ? 0.26885 0.26749 0.29384 0.01366  -0.01932 -0.01971 185 LEU A CD2   
1500 N  N     . GLN A 189 ? 0.22518 0.24552 0.27116 0.01229  -0.02018 -0.01962 186 GLN A N     
1501 C  CA    . GLN A 189 ? 0.28321 0.31057 0.33817 0.01110  -0.02080 -0.01819 186 GLN A CA    
1502 C  C     . GLN A 189 ? 0.30474 0.32925 0.35893 0.00768  -0.02608 -0.01600 186 GLN A C     
1503 O  O     . GLN A 189 ? 0.27824 0.30917 0.34188 0.00538  -0.02782 -0.01318 186 GLN A O     
1504 C  CB    . GLN A 189 ? 0.31813 0.34815 0.37459 0.01379  -0.01831 -0.01920 186 GLN A CB    
1505 C  CG    . GLN A 189 ? 0.42309 0.45725 0.48637 0.01320  -0.01947 -0.01748 186 GLN A CG    
1506 C  CD    . GLN A 189 ? 0.64824 0.68256 0.71104 0.01521  -0.01762 -0.01819 186 GLN A CD    
1507 O  OE1   . GLN A 189 ? 0.56390 0.59355 0.61974 0.01592  -0.01779 -0.01862 186 GLN A OE1   
1508 N  NE2   . GLN A 189 ? 0.62816 0.66673 0.69740 0.01622  -0.01535 -0.01813 186 GLN A NE2   
1509 N  N     . ALA A 190 ? 0.24821 0.26272 0.29079 0.00729  -0.02874 -0.01681 187 ALA A N     
1510 C  CA    . ALA A 190 ? 0.31497 0.32432 0.35390 0.00291  -0.03538 -0.01465 187 ALA A CA    
1511 C  C     . ALA A 190 ? 0.33181 0.34019 0.37259 -0.00194 -0.03928 -0.01262 187 ALA A C     
1512 O  O     . ALA A 190 ? 0.27066 0.28321 0.31859 -0.00649 -0.04462 -0.00889 187 ALA A O     
1513 C  CB    . ALA A 190 ? 0.32649 0.32169 0.34821 0.00360  -0.03692 -0.01642 187 ALA A CB    
1514 N  N     . THR A 191 ? 0.31405 0.31743 0.34933 -0.00125 -0.03695 -0.01433 188 THR A N     
1515 C  CA    . THR A 191 ? 0.33749 0.33903 0.37393 -0.00628 -0.04034 -0.01214 188 THR A CA    
1516 C  C     . THR A 191 ? 0.27099 0.28766 0.32518 -0.00781 -0.03873 -0.00864 188 THR A C     
1517 O  O     . THR A 191 ? 0.28104 0.30107 0.34207 -0.01335 -0.04319 -0.00449 188 THR A O     
1518 C  CB    . THR A 191 ? 0.30949 0.30176 0.33579 -0.00433 -0.03755 -0.01452 188 THR A CB    
1519 O  OG1   . THR A 191 ? 0.35443 0.33189 0.36399 -0.00191 -0.03792 -0.01730 188 THR A OG1   
1520 C  CG2   . THR A 191 ? 0.30857 0.29728 0.33483 -0.01016 -0.04123 -0.01199 188 THR A CG2   
1521 N  N     . LEU A 192 ? 0.25820 0.28357 0.31962 -0.00310 -0.03228 -0.00986 189 LEU A N     
1522 C  CA    . LEU A 192 ? 0.24985 0.28757 0.32580 -0.00330 -0.02915 -0.00678 189 LEU A CA    
1523 C  C     . LEU A 192 ? 0.25946 0.30546 0.34698 -0.00484 -0.03214 -0.00276 189 LEU A C     
1524 O  O     . LEU A 192 ? 0.25517 0.30962 0.35470 -0.00784 -0.03305 0.00215  189 LEU A O     
1525 C  CB    . LEU A 192 ? 0.24392 0.28550 0.32115 0.00199  -0.02216 -0.00951 189 LEU A CB    
1526 C  CG    . LEU A 192 ? 0.28257 0.33369 0.37087 0.00308  -0.01707 -0.00710 189 LEU A CG    
1527 C  CD1   . LEU A 192 ? 0.26569 0.31811 0.35655 -0.00052 -0.01677 -0.00403 189 LEU A CD1   
1528 C  CD2   . LEU A 192 ? 0.32368 0.37428 0.40839 0.00758  -0.01139 -0.01054 189 LEU A CD2   
1529 N  N     . GLY A 193 ? 0.26038 0.30471 0.34533 -0.00270 -0.03360 -0.00403 190 GLY A N     
1530 C  CA    . GLY A 193 ? 0.31450 0.36604 0.40998 -0.00385 -0.03726 0.00031  190 GLY A CA    
1531 C  C     . GLY A 193 ? 0.29955 0.35009 0.39668 -0.01083 -0.04587 0.00478  190 GLY A C     
1532 O  O     . GLY A 193 ? 0.30957 0.37111 0.42194 -0.01310 -0.04844 0.01074  190 GLY A O     
1533 N  N     . GLU A 194 ? 0.31888 0.35577 0.40027 -0.01437 -0.05044 0.00235  191 GLU A N     
1534 C  CA    . GLU A 194 ? 0.35323 0.38523 0.43220 -0.02231 -0.05962 0.00603  191 GLU A CA    
1535 C  C     . GLU A 194 ? 0.37855 0.42086 0.47201 -0.02642 -0.05935 0.01104  191 GLU A C     
1536 O  O     . GLU A 194 ? 0.33505 0.38633 0.44168 -0.03173 -0.06526 0.01765  191 GLU A O     
1537 C  CB    . GLU A 194 ? 0.42768 0.43983 0.48385 -0.02392 -0.06222 0.00140  191 GLU A CB    
1538 C  CG    . GLU A 194 ? 0.54470 0.54329 0.58720 -0.02992 -0.07228 0.00235  191 GLU A CG    
1539 C  CD    . GLU A 194 ? 0.64510 0.62176 0.66307 -0.02985 -0.07245 -0.00275 191 GLU A CD    
1540 O  OE1   . GLU A 194 ? 0.46063 0.43064 0.47456 -0.03446 -0.07493 -0.00205 191 GLU A OE1   
1541 O  OE2   . GLU A 194 ? 0.53088 0.49676 0.53380 -0.02495 -0.06955 -0.00704 191 GLU A OE2   
1542 N  N     . LEU A 195 ? 0.29676 0.33846 0.38856 -0.02421 -0.05263 0.00867  192 LEU A N     
1543 C  CA    . LEU A 195 ? 0.30281 0.35207 0.40571 -0.02870 -0.05215 0.01359  192 LEU A CA    
1544 C  C     . LEU A 195 ? 0.28950 0.35795 0.41427 -0.02590 -0.04636 0.01871  192 LEU A C     
1545 O  O     . LEU A 195 ? 0.28407 0.36255 0.42305 -0.03066 -0.04771 0.02546  192 LEU A O     
1546 C  CB    . LEU A 195 ? 0.39894 0.43949 0.49096 -0.02750 -0.04735 0.00985  192 LEU A CB    
1547 C  CG    . LEU A 195 ? 0.39182 0.43651 0.48453 -0.02000 -0.03731 0.00635  192 LEU A CG    
1548 C  CD1   . LEU A 195 ? 0.30411 0.36136 0.41121 -0.02020 -0.03144 0.01092  192 LEU A CD1   
1549 C  CD2   . LEU A 195 ? 0.38138 0.41187 0.45678 -0.01826 -0.03609 0.00127  192 LEU A CD2   
1550 N  N     . LEU A 196 ? 0.22115 0.29437 0.34882 -0.01827 -0.03964 0.01608  193 LEU A N     
1551 C  CA    . LEU A 196 ? 0.29774 0.38673 0.44437 -0.01459 -0.03395 0.02094  193 LEU A CA    
1552 C  C     . LEU A 196 ? 0.35717 0.45465 0.51642 -0.01623 -0.04041 0.02661  193 LEU A C     
1553 O  O     . LEU A 196 ? 0.32740 0.43883 0.50441 -0.01268 -0.03606 0.03187  193 LEU A O     
1554 C  CB    . LEU A 196 ? 0.31096 0.39903 0.45369 -0.00608 -0.02467 0.01587  193 LEU A CB    
1555 C  CG    . LEU A 196 ? 0.30178 0.38412 0.43477 -0.00365 -0.01758 0.01144  193 LEU A CG    
1556 C  CD1   . LEU A 196 ? 0.30840 0.38961 0.43805 0.00362  -0.01019 0.00731  193 LEU A CD1   
1557 C  CD2   . LEU A 196 ? 0.23150 0.32096 0.37344 -0.00603 -0.01361 0.01636  193 LEU A CD2   
1558 N  N     . ARG A 197 ? 0.32710 0.41560 0.47662 -0.02102 -0.05044 0.02585  194 ARG A N     
1559 C  CA    . ARG A 197 ? 0.35932 0.45391 0.51812 -0.02324 -0.05836 0.03127  194 ARG A CA    
1560 C  C     . ARG A 197 ? 0.31418 0.41546 0.48042 -0.01479 -0.05247 0.03099  194 ARG A C     
1561 O  O     . ARG A 197 ? 0.31001 0.42543 0.49539 -0.01304 -0.05241 0.03797  194 ARG A O     
1562 C  CB    . ARG A 197 ? 0.31398 0.42270 0.49282 -0.02985 -0.06361 0.04111  194 ARG A CB    
1563 C  CG    . ARG A 197 ? 0.35513 0.45536 0.52552 -0.03914 -0.06982 0.04154  194 ARG A CG    
1564 C  CD    . ARG A 197 ? 0.40726 0.52284 0.59934 -0.04674 -0.07497 0.05220  194 ARG A CD    
1565 N  NE    . ARG A 197 ? 0.40797 0.51237 0.58950 -0.05703 -0.08293 0.05267  194 ARG A NE    
1566 C  CZ    . ARG A 197 ? 0.51551 0.62940 0.71109 -0.06390 -0.08415 0.05992  194 ARG A CZ    
1567 N  NH1   . ARG A 197 ? 0.43807 0.57409 0.65979 -0.06106 -0.07687 0.06766  194 ARG A NH1   
1568 N  NH2   . ARG A 197 ? 0.45126 0.55129 0.63385 -0.07375 -0.09240 0.05970  194 ARG A NH2   
1569 N  N     . HIS A 198 ? 0.28357 0.37458 0.43504 -0.00940 -0.04725 0.02332  195 HIS A N     
1570 C  CA    . HIS A 198 ? 0.30537 0.39882 0.46005 -0.00230 -0.04268 0.02236  195 HIS A CA    
1571 C  C     . HIS A 198 ? 0.35688 0.45074 0.51374 -0.00416 -0.05152 0.02626  195 HIS A C     
1572 O  O     . HIS A 198 ? 0.40104 0.48410 0.54390 -0.00905 -0.05956 0.02453  195 HIS A O     
1573 C  CB    . HIS A 198 ? 0.41962 0.50129 0.55740 0.00193  -0.03727 0.01399  195 HIS A CB    
1574 C  CG    . HIS A 198 ? 0.53177 0.61376 0.66837 0.00551  -0.02794 0.01050  195 HIS A CG    
1575 N  ND1   . HIS A 198 ? 0.60336 0.67578 0.72566 0.00757  -0.02436 0.00381  195 HIS A ND1   
1576 C  CD2   . HIS A 198 ? 0.46613 0.55658 0.61356 0.00751  -0.02143 0.01320  195 HIS A CD2   
1577 C  CE1   . HIS A 198 ? 0.42618 0.50027 0.54945 0.01003  -0.01725 0.00234  195 HIS A CE1   
1578 N  NE2   . HIS A 198 ? 0.51166 0.59578 0.64894 0.01029  -0.01481 0.00766  195 HIS A NE2   
1579 N  N     . LEU A 199 ? 0.31416 0.41921 0.48724 0.00023  -0.04971 0.03162  196 LEU A N     
1580 C  CA    . LEU A 199 ? 0.37231 0.47881 0.54901 -0.00065 -0.05794 0.03625  196 LEU A CA    
1581 C  C     . LEU A 199 ? 0.33870 0.43879 0.50821 0.00633  -0.05303 0.03229  196 LEU A C     
1582 O  O     . LEU A 199 ? 0.33337 0.43340 0.50349 0.01268  -0.04290 0.02880  196 LEU A O     
1583 C  CB    . LEU A 199 ? 0.38811 0.51285 0.59044 -0.00055 -0.06037 0.04675  196 LEU A CB    
1584 C  CG    . LEU A 199 ? 0.35546 0.48928 0.56900 -0.00845 -0.06598 0.05277  196 LEU A CG    
1585 C  CD1   . LEU A 199 ? 0.38142 0.53372 0.62011 -0.00638 -0.06470 0.06307  196 LEU A CD1   
1586 C  CD2   . LEU A 199 ? 0.40253 0.52564 0.60212 -0.01858 -0.07981 0.05266  196 LEU A CD2   
1587 N  N     . MET A 200 ? 0.30372 0.39696 0.46487 0.00462  -0.06055 0.03293  197 MET A N     
1588 C  CA    . MET A 200 ? 0.33827 0.42339 0.49006 0.01003  -0.05632 0.02896  197 MET A CA    
1589 C  C     . MET A 200 ? 0.33127 0.42603 0.49997 0.01647  -0.05352 0.03476  197 MET A C     
1590 O  O     . MET A 200 ? 0.28313 0.38990 0.46896 0.01568  -0.05860 0.04305  197 MET A O     
1591 C  CB    . MET A 200 ? 0.31573 0.38755 0.44877 0.00590  -0.06416 0.02693  197 MET A CB    
1592 C  CG    . MET A 200 ? 0.29514 0.35942 0.41987 0.01014  -0.06199 0.02512  197 MET A CG    
1593 S  SD    . MET A 200 ? 0.30593 0.35639 0.41098 0.00501  -0.07238 0.02568  197 MET A SD    
1594 C  CE    . MET A 200 ? 0.31750 0.35777 0.40565 -0.00172 -0.07577 0.02110  197 MET A CE    
1595 N  N     . ASP A 201 ? 0.32488 0.41461 0.48966 0.02297  -0.04501 0.03079  198 ASP A N     
1596 C  CA    . ASP A 201 ? 0.31302 0.40845 0.49100 0.03026  -0.04101 0.03552  198 ASP A CA    
1597 C  C     . ASP A 201 ? 0.36137 0.45779 0.54264 0.02928  -0.05059 0.04189  198 ASP A C     
1598 O  O     . ASP A 201 ? 0.34276 0.42830 0.50797 0.02543  -0.05649 0.03927  198 ASP A O     
1599 C  CB    . ASP A 201 ? 0.39922 0.48396 0.56668 0.03580  -0.03188 0.02916  198 ASP A CB    
1600 C  CG    . ASP A 201 ? 0.43263 0.51842 0.60913 0.04354  -0.02801 0.03330  198 ASP A CG    
1601 O  OD1   . ASP A 201 ? 0.48475 0.57803 0.67440 0.04930  -0.02086 0.03623  198 ASP A OD1   
1602 O  OD2   . ASP A 201 ? 0.39807 0.47654 0.56805 0.04425  -0.03161 0.03394  198 ASP A OD2   
1603 N  N     . PRO A 202 ? 0.36775 0.47692 0.56943 0.03308  -0.05208 0.05078  199 PRO A N     
1604 C  CA    . PRO A 202 ? 0.31788 0.42892 0.52350 0.03143  -0.06301 0.05799  199 PRO A CA    
1605 C  C     . PRO A 202 ? 0.32816 0.42580 0.52003 0.03490  -0.06259 0.05545  199 PRO A C     
1606 O  O     . PRO A 202 ? 0.32616 0.41766 0.50862 0.03059  -0.07236 0.05750  199 PRO A O     
1607 C  CB    . PRO A 202 ? 0.36367 0.49215 0.59551 0.03652  -0.06146 0.06789  199 PRO A CB    
1608 C  CG    . PRO A 202 ? 0.47000 0.60520 0.70921 0.03886  -0.05047 0.06557  199 PRO A CG    
1609 C  CD    . PRO A 202 ? 0.41677 0.53854 0.63837 0.04004  -0.04309 0.05508  199 PRO A CD    
1610 N  N     . GLY A 203 ? 0.33317 0.42501 0.52270 0.04225  -0.05175 0.05144  200 GLY A N     
1611 C  CA    . GLY A 203 ? 0.32742 0.40524 0.50267 0.04449  -0.05107 0.04872  200 GLY A CA    
1612 C  C     . GLY A 203 ? 0.33582 0.40066 0.48841 0.03792  -0.05323 0.04128  200 GLY A C     
1613 O  O     . GLY A 203 ? 0.30653 0.36177 0.44681 0.03617  -0.05786 0.04152  200 GLY A O     
1614 N  N     . THR A 204 ? 0.30148 0.36586 0.44838 0.03466  -0.04942 0.03510  201 THR A N     
1615 C  CA    . THR A 204 ? 0.25225 0.30577 0.37945 0.02923  -0.05073 0.02877  201 THR A CA    
1616 C  C     . THR A 204 ? 0.30457 0.35551 0.42409 0.02303  -0.06173 0.03180  201 THR A C     
1617 O  O     . THR A 204 ? 0.31216 0.35152 0.41460 0.02066  -0.06404 0.02963  201 THR A O     
1618 C  CB    . THR A 204 ? 0.35882 0.41377 0.48379 0.02752  -0.04513 0.02282  201 THR A CB    
1619 O  OG1   . THR A 204 ? 0.35442 0.40724 0.48041 0.03239  -0.03554 0.01901  201 THR A OG1   
1620 C  CG2   . THR A 204 ? 0.28238 0.32803 0.38944 0.02239  -0.04697 0.01765  201 THR A CG2   
1621 N  N     . PHE A 205 ? 0.24595 0.30685 0.37715 0.02002  -0.06862 0.03713  202 PHE A N     
1622 C  CA    . PHE A 205 ? 0.31645 0.37326 0.43922 0.01328  -0.08070 0.04058  202 PHE A CA    
1623 C  C     . PHE A 205 ? 0.31326 0.36446 0.43133 0.01450  -0.08654 0.04526  202 PHE A C     
1624 O  O     . PHE A 205 ? 0.28266 0.32030 0.38038 0.01093  -0.09088 0.04332  202 PHE A O     
1625 C  CB    . PHE A 205 ? 0.28679 0.35683 0.42618 0.00929  -0.08806 0.04707  202 PHE A CB    
1626 C  CG    . PHE A 205 ? 0.33551 0.40024 0.46582 0.00139  -0.10233 0.05140  202 PHE A CG    
1627 C  CD1   . PHE A 205 ? 0.32577 0.37727 0.43501 -0.00538 -0.10628 0.04629  202 PHE A CD1   
1628 C  CD2   . PHE A 205 ? 0.32497 0.39619 0.46606 0.00096  -0.11192 0.06061  202 PHE A CD2   
1629 C  CE1   . PHE A 205 ? 0.31128 0.35421 0.40808 -0.01305 -0.11973 0.04976  202 PHE A CE1   
1630 C  CE2   . PHE A 205 ? 0.34935 0.41387 0.47971 -0.00721 -0.12637 0.06469  202 PHE A CE2   
1631 C  CZ    . PHE A 205 ? 0.34486 0.39413 0.45172 -0.01455 -0.13032 0.05889  202 PHE A CZ    
1632 N  N     . THR A 206 ? 0.27382 0.33460 0.40991 0.02006  -0.08621 0.05179  203 THR A N     
1633 C  CA    . THR A 206 ? 0.30265 0.35899 0.43599 0.02126  -0.09303 0.05763  203 THR A CA    
1634 C  C     . THR A 206 ? 0.35451 0.39477 0.46776 0.02297  -0.08781 0.05221  203 THR A C     
1635 O  O     . THR A 206 ? 0.33843 0.36813 0.43655 0.02007  -0.09455 0.05403  203 THR A O     
1636 C  CB    . THR A 206 ? 0.35723 0.42710 0.51516 0.02853  -0.09175 0.06570  203 THR A CB    
1637 O  OG1   . THR A 206 ? 0.41587 0.50246 0.59401 0.02625  -0.09672 0.07190  203 THR A OG1   
1638 C  CG2   . THR A 206 ? 0.40988 0.47536 0.56586 0.03015  -0.09950 0.07265  203 THR A CG2   
1639 N  N     . SER A 207 ? 0.33270 0.37038 0.44461 0.02699  -0.07611 0.04579  204 SER A N     
1640 C  CA    . SER A 207 ? 0.37953 0.40343 0.47457 0.02784  -0.07117 0.04150  204 SER A CA    
1641 C  C     . SER A 207 ? 0.35510 0.36827 0.42869 0.02180  -0.07305 0.03684  204 SER A C     
1642 O  O     . SER A 207 ? 0.31344 0.31503 0.37146 0.02092  -0.07339 0.03665  204 SER A O     
1643 C  CB    . SER A 207 ? 0.36378 0.38726 0.46244 0.03237  -0.05943 0.03611  204 SER A CB    
1644 O  OG    . SER A 207 ? 0.48224 0.51131 0.59664 0.03911  -0.05654 0.04031  204 SER A OG    
1645 N  N     . ASN A 208 ? 0.28268 0.29860 0.35444 0.01799  -0.07365 0.03337  205 ASN A N     
1646 C  CA    . ASN A 208 ? 0.27338 0.27776 0.32407 0.01378  -0.07322 0.02843  205 ASN A CA    
1647 C  C     . ASN A 208 ? 0.26325 0.25992 0.30040 0.00822  -0.08412 0.03133  205 ASN A C     
1648 O  O     . ASN A 208 ? 0.29805 0.28121 0.31370 0.00586  -0.08351 0.02817  205 ASN A O     
1649 C  CB    . ASN A 208 ? 0.24460 0.25251 0.29674 0.01316  -0.06686 0.02229  205 ASN A CB    
1650 C  CG    . ASN A 208 ? 0.36415 0.37339 0.41991 0.01708  -0.05635 0.01806  205 ASN A CG    
1651 O  OD1   . ASN A 208 ? 0.28408 0.28534 0.32740 0.01690  -0.05155 0.01485  205 ASN A OD1   
1652 N  ND2   . ASN A 208 ? 0.29559 0.31443 0.36809 0.02060  -0.05262 0.01855  205 ASN A ND2   
1653 N  N     . PHE A 209 ? 0.28961 0.29380 0.33796 0.00595  -0.09401 0.03756  206 PHE A N     
1654 C  CA    . PHE A 209 ? 0.32436 0.31954 0.35811 -0.00064 -0.10611 0.04055  206 PHE A CA    
1655 C  C     . PHE A 209 ? 0.33968 0.33134 0.37090 -0.00091 -0.11510 0.04785  206 PHE A C     
1656 O  O     . PHE A 209 ? 0.32172 0.30273 0.33662 -0.00678 -0.12593 0.05043  206 PHE A O     
1657 C  CB    . PHE A 209 ? 0.26368 0.26845 0.30943 -0.00545 -0.11327 0.04293  206 PHE A CB    
1658 C  CG    . PHE A 209 ? 0.33523 0.33569 0.37248 -0.00760 -0.10787 0.03569  206 PHE A CG    
1659 C  CD1   . PHE A 209 ? 0.30435 0.31440 0.35462 -0.00318 -0.09680 0.03146  206 PHE A CD1   
1660 C  CD2   . PHE A 209 ? 0.31259 0.29747 0.32690 -0.01375 -0.11376 0.03309  206 PHE A CD2   
1661 C  CE1   . PHE A 209 ? 0.32401 0.32995 0.36649 -0.00475 -0.09204 0.02530  206 PHE A CE1   
1662 C  CE2   . PHE A 209 ? 0.31177 0.29150 0.31781 -0.01480 -0.10831 0.02669  206 PHE A CE2   
1663 C  CZ    . PHE A 209 ? 0.25349 0.24468 0.27466 -0.01026 -0.09762 0.02306  206 PHE A CZ    
1664 N  N     . ASN A 210 ? 0.30275 0.30104 0.34753 0.00519  -0.11116 0.05123  207 ASN A N     
1665 C  CA    . ASN A 210 ? 0.30968 0.30205 0.34907 0.00573  -0.11842 0.05779  207 ASN A CA    
1666 C  C     . ASN A 210 ? 0.30668 0.27823 0.31450 0.00229  -0.11914 0.05452  207 ASN A C     
1667 O  O     . ASN A 210 ? 0.35398 0.31797 0.35012 0.00405  -0.10834 0.04788  207 ASN A O     
1668 C  CB    . ASN A 210 ? 0.29297 0.29123 0.34717 0.01377  -0.11067 0.05982  207 ASN A CB    
1669 C  CG    . ASN A 210 ? 0.36945 0.36424 0.42322 0.01535  -0.11880 0.06823  207 ASN A CG    
1670 O  OD1   . ASN A 210 ? 0.36305 0.34452 0.39609 0.01094  -0.12640 0.07003  207 ASN A OD1   
1671 N  ND2   . ASN A 210 ? 0.36209 0.36772 0.43765 0.02208  -0.11691 0.07358  207 ASN A ND2   
1672 N  N     . ASN A 211 ? 0.32312 0.28520 0.31668 -0.00276 -0.13188 0.05960  208 ASN A N     
1673 C  CA    . ASN A 211 ? 0.34065 0.28084 0.30086 -0.00642 -0.13261 0.05635  208 ASN A CA    
1674 C  C     . ASN A 211 ? 0.40721 0.33697 0.35534 -0.00413 -0.13296 0.06032  208 ASN A C     
1675 O  O     . ASN A 211 ? 0.39259 0.30330 0.31189 -0.00729 -0.13516 0.05951  208 ASN A O     
1676 C  CB    . ASN A 211 ? 0.35008 0.28034 0.29373 -0.01474 -0.14610 0.05776  208 ASN A CB    
1677 C  CG    . ASN A 211 ? 0.42187 0.35797 0.37525 -0.01849 -0.16276 0.06787  208 ASN A CG    
1678 O  OD1   . ASN A 211 ? 0.40354 0.35382 0.37989 -0.01393 -0.16391 0.07432  208 ASN A OD1   
1679 N  ND2   . ASN A 211 ? 0.43844 0.36267 0.37358 -0.02694 -0.17621 0.06966  208 ASN A ND2   
1680 N  N     . LYS A 212 ? 0.37551 0.31558 0.34327 0.00160  -0.12996 0.06447  209 LYS A N     
1681 C  CA    . LYS A 212 ? 0.39497 0.32399 0.35068 0.00404  -0.12837 0.06760  209 LYS A CA    
1682 C  C     . LYS A 212 ? 0.34931 0.26825 0.28944 0.00555  -0.11414 0.06040  209 LYS A C     
1683 O  O     . LYS A 212 ? 0.35467 0.27903 0.29990 0.00625  -0.10512 0.05365  209 LYS A O     
1684 C  CB    . LYS A 212 ? 0.37295 0.31403 0.35328 0.01031  -0.12818 0.07374  209 LYS A CB    
1685 C  CG    . LYS A 212 ? 0.40713 0.35894 0.40663 0.01622  -0.11464 0.06891  209 LYS A CG    
1686 C  CD    . LYS A 212 ? 0.46466 0.42661 0.48738 0.02296  -0.11534 0.07551  209 LYS A CD    
1687 C  CE    . LYS A 212 ? 0.51276 0.48495 0.55425 0.02845  -0.10343 0.07081  209 LYS A CE    
1688 N  NZ    . LYS A 212 ? 0.53532 0.49715 0.56512 0.02941  -0.09188 0.06465  209 LYS A NZ    
1689 N  N     . PRO A 213 ? 0.36629 0.27090 0.28757 0.00581  -0.11212 0.06236  210 PRO A N     
1690 C  CA    . PRO A 213 ? 0.36942 0.26688 0.27941 0.00725  -0.09808 0.05702  210 PRO A CA    
1691 C  C     . PRO A 213 ? 0.41052 0.32207 0.34376 0.01137  -0.08750 0.05314  210 PRO A C     
1692 O  O     . PRO A 213 ? 0.38793 0.30783 0.34001 0.01501  -0.08805 0.05634  210 PRO A O     
1693 C  CB    . PRO A 213 ? 0.42808 0.31243 0.32320 0.00775  -0.09885 0.06248  210 PRO A CB    
1694 C  CG    . PRO A 213 ? 0.42844 0.30508 0.31159 0.00422  -0.11430 0.06845  210 PRO A CG    
1695 C  CD    . PRO A 213 ? 0.39612 0.29025 0.30499 0.00443  -0.12273 0.07020  210 PRO A CD    
1696 N  N     . TRP A 214 ? 0.38409 0.29709 0.31478 0.01095  -0.07795 0.04639  211 TRP A N     
1697 C  CA    . TRP A 214 ? 0.31998 0.24545 0.27040 0.01376  -0.06895 0.04217  211 TRP A CA    
1698 C  C     . TRP A 214 ? 0.40965 0.33216 0.36191 0.01576  -0.06127 0.04338  211 TRP A C     
1699 O  O     . TRP A 214 ? 0.36366 0.27582 0.29954 0.01432  -0.05648 0.04398  211 TRP A O     
1700 C  CB    . TRP A 214 ? 0.30677 0.23367 0.25224 0.01243  -0.06203 0.03553  211 TRP A CB    
1701 C  CG    . TRP A 214 ? 0.31153 0.25173 0.27662 0.01444  -0.05512 0.03107  211 TRP A CG    
1702 C  CD1   . TRP A 214 ? 0.29373 0.23611 0.26163 0.01516  -0.04495 0.02786  211 TRP A CD1   
1703 C  CD2   . TRP A 214 ? 0.30470 0.25728 0.28822 0.01551  -0.05824 0.02982  211 TRP A CD2   
1704 N  NE1   . TRP A 214 ? 0.29639 0.25043 0.28170 0.01649  -0.04223 0.02432  211 TRP A NE1   
1705 C  CE2   . TRP A 214 ? 0.34482 0.30496 0.33941 0.01704  -0.04958 0.02530  211 TRP A CE2   
1706 C  CE3   . TRP A 214 ? 0.30485 0.26328 0.29703 0.01501  -0.06763 0.03272  211 TRP A CE3   
1707 C  CZ2   . TRP A 214 ? 0.29279 0.26439 0.30448 0.01856  -0.04937 0.02319  211 TRP A CZ2   
1708 C  CZ3   . TRP A 214 ? 0.30138 0.27289 0.31266 0.01658  -0.06673 0.03105  211 TRP A CZ3   
1709 C  CH2   . TRP A 214 ? 0.29438 0.27156 0.31421 0.01859  -0.05733 0.02612  211 TRP A CH2   
1710 N  N     . VAL A 215 ? 0.35106 0.28168 0.32240 0.01896  -0.05958 0.04384  212 VAL A N     
1711 C  CA    . VAL A 215 ? 0.34338 0.26961 0.31638 0.02021  -0.05307 0.04484  212 VAL A CA    
1712 C  C     . VAL A 215 ? 0.31492 0.24873 0.30089 0.02092  -0.04480 0.03961  212 VAL A C     
1713 O  O     . VAL A 215 ? 0.38882 0.31799 0.37463 0.02049  -0.03929 0.03987  212 VAL A O     
1714 C  CB    . VAL A 215 ? 0.40891 0.33183 0.38795 0.02361  -0.05859 0.05113  212 VAL A CB    
1715 C  CG1   . VAL A 215 ? 0.39811 0.31016 0.36023 0.02199  -0.06601 0.05706  212 VAL A CG1   
1716 C  CG2   . VAL A 215 ? 0.44983 0.38448 0.44824 0.02746  -0.06344 0.05197  212 VAL A CG2   
1717 N  N     . SER A 216 ? 0.30925 0.25348 0.30550 0.02142  -0.04426 0.03524  213 SER A N     
1718 C  CA    . SER A 216 ? 0.33735 0.28763 0.34411 0.02177  -0.03723 0.03045  213 SER A CA    
1719 C  C     . SER A 216 ? 0.35017 0.29939 0.34909 0.01822  -0.03023 0.02743  213 SER A C     
1720 O  O     . SER A 216 ? 0.30912 0.25585 0.29631 0.01647  -0.02990 0.02735  213 SER A O     
1721 C  CB    . SER A 216 ? 0.34872 0.31022 0.36813 0.02343  -0.03868 0.02719  213 SER A CB    
1722 O  OG    . SER A 216 ? 0.32878 0.29500 0.35464 0.02295  -0.03217 0.02215  213 SER A OG    
1723 N  N     . GLY A 217 ? 0.31196 0.26271 0.31727 0.01723  -0.02457 0.02525  214 GLY A N     
1724 C  CA    . GLY A 217 ? 0.26733 0.22090 0.26985 0.01396  -0.01822 0.02305  214 GLY A CA    
1725 C  C     . GLY A 217 ? 0.30287 0.26592 0.30996 0.01420  -0.01695 0.01846  214 GLY A C     
1726 O  O     . GLY A 217 ? 0.26702 0.23315 0.27165 0.01242  -0.01188 0.01733  214 GLY A O     
1727 N  N     . GLN A 218 ? 0.25434 0.22238 0.26874 0.01654  -0.02106 0.01641  215 GLN A N     
1728 C  CA    . GLN A 218 ? 0.22935 0.20551 0.24796 0.01661  -0.02013 0.01226  215 GLN A CA    
1729 C  C     . GLN A 218 ? 0.30726 0.28106 0.31444 0.01617  -0.02152 0.01228  215 GLN A C     
1730 O  O     . GLN A 218 ? 0.24870 0.21687 0.24828 0.01642  -0.02708 0.01491  215 GLN A O     
1731 C  CB    . GLN A 218 ? 0.30241 0.28432 0.33218 0.01901  -0.02367 0.01082  215 GLN A CB    
1732 C  CG    . GLN A 218 ? 0.30428 0.28784 0.34344 0.01989  -0.02059 0.00891  215 GLN A CG    
1733 C  CD    . GLN A 218 ? 0.34291 0.33176 0.38467 0.01784  -0.01639 0.00482  215 GLN A CD    
1734 O  OE1   . GLN A 218 ? 0.32391 0.31811 0.36525 0.01753  -0.01635 0.00284  215 GLN A OE1   
1735 N  NE2   . GLN A 218 ? 0.27054 0.25699 0.31414 0.01605  -0.01336 0.00390  215 GLN A NE2   
1736 N  N     . HIS A 219 ? 0.27932 0.25654 0.28468 0.01565  -0.01696 0.00949  216 HIS A N     
1737 C  CA    . HIS A 219 ? 0.25659 0.23022 0.25070 0.01595  -0.01805 0.00834  216 HIS A CA    
1738 C  C     . HIS A 219 ? 0.30971 0.29093 0.31205 0.01648  -0.01878 0.00446  216 HIS A C     
1739 O  O     . HIS A 219 ? 0.25373 0.24049 0.26068 0.01681  -0.01351 0.00220  216 HIS A O     
1740 C  CB    . HIS A 219 ? 0.28352 0.25241 0.26577 0.01613  -0.01112 0.00897  216 HIS A CB    
1741 C  CG    . HIS A 219 ? 0.28909 0.24996 0.25578 0.01701  -0.01208 0.00761  216 HIS A CG    
1742 N  ND1   . HIS A 219 ? 0.32028 0.26928 0.27122 0.01617  -0.01787 0.00946  216 HIS A ND1   
1743 C  CD2   . HIS A 219 ? 0.29309 0.25458 0.25664 0.01847  -0.00894 0.00454  216 HIS A CD2   
1744 C  CE1   . HIS A 219 ? 0.34571 0.28687 0.28267 0.01668  -0.01806 0.00725  216 HIS A CE1   
1745 N  NE2   . HIS A 219 ? 0.32968 0.27809 0.27417 0.01845  -0.01231 0.00421  216 HIS A NE2   
1746 N  N     . GLU A 220 ? 0.26848 0.25053 0.27355 0.01633  -0.02558 0.00445  217 GLU A N     
1747 C  CA    . GLU A 220 ? 0.25747 0.24546 0.26891 0.01629  -0.02710 0.00154  217 GLU A CA    
1748 C  C     . GLU A 220 ? 0.28575 0.26731 0.28706 0.01465  -0.03399 0.00234  217 GLU A C     
1749 O  O     . GLU A 220 ? 0.25847 0.23438 0.25388 0.01358  -0.03976 0.00576  217 GLU A O     
1750 C  CB    . GLU A 220 ? 0.25233 0.24928 0.28034 0.01714  -0.02863 0.00148  217 GLU A CB    
1751 C  CG    . GLU A 220 ? 0.28374 0.28312 0.31934 0.01816  -0.02399 0.00134  217 GLU A CG    
1752 C  CD    . GLU A 220 ? 0.35354 0.35805 0.40175 0.01999  -0.02526 0.00166  217 GLU A CD    
1753 O  OE1   . GLU A 220 ? 0.32769 0.33087 0.37882 0.02141  -0.02897 0.00519  217 GLU A OE1   
1754 O  OE2   . GLU A 220 ? 0.33208 0.34163 0.38689 0.02042  -0.02230 -0.00127 217 GLU A OE2   
1755 N  N     . THR A 221 ? 0.25479 0.23631 0.25348 0.01403  -0.03413 -0.00050 218 THR A N     
1756 C  CA    . THR A 221 ? 0.28982 0.26331 0.27732 0.01135  -0.04139 -0.00002 218 THR A CA    
1757 C  C     . THR A 221 ? 0.27863 0.26023 0.27815 0.00982  -0.04508 -0.00083 218 THR A C     
1758 O  O     . THR A 221 ? 0.24339 0.22992 0.24832 0.01108  -0.04013 -0.00395 218 THR A O     
1759 C  CB    . THR A 221 ? 0.34049 0.30080 0.30729 0.01179  -0.03794 -0.00238 218 THR A CB    
1760 O  OG1   . THR A 221 ? 0.29781 0.25142 0.25414 0.01342  -0.03331 -0.00090 218 THR A OG1   
1761 C  CG2   . THR A 221 ? 0.29130 0.23943 0.24280 0.00807  -0.04663 -0.00208 218 THR A CG2   
1762 N  N     . TYR A 222 ? 0.29036 0.27397 0.29480 0.00701  -0.05383 0.00269  219 TYR A N     
1763 C  CA    . TYR A 222 ? 0.25020 0.24140 0.26589 0.00462  -0.05826 0.00336  219 TYR A CA    
1764 C  C     . TYR A 222 ? 0.27868 0.25845 0.27912 -0.00042 -0.06643 0.00382  219 TYR A C     
1765 O  O     . TYR A 222 ? 0.27542 0.24487 0.26232 -0.00274 -0.07260 0.00611  219 TYR A O     
1766 C  CB    . TYR A 222 ? 0.24528 0.24889 0.28049 0.00508  -0.06203 0.00825  219 TYR A CB    
1767 C  CG    . TYR A 222 ? 0.27781 0.29093 0.32720 0.00989  -0.05363 0.00694  219 TYR A CG    
1768 C  CD1   . TYR A 222 ? 0.29451 0.30468 0.34137 0.01284  -0.04930 0.00677  219 TYR A CD1   
1769 C  CD2   . TYR A 222 ? 0.30143 0.32453 0.36459 0.01099  -0.05018 0.00590  219 TYR A CD2   
1770 C  CE1   . TYR A 222 ? 0.36607 0.38193 0.42309 0.01635  -0.04249 0.00535  219 TYR A CE1   
1771 C  CE2   . TYR A 222 ? 0.29685 0.32541 0.36923 0.01507  -0.04284 0.00432  219 TYR A CE2   
1772 C  CZ    . TYR A 222 ? 0.35973 0.38405 0.42855 0.01750  -0.03943 0.00392  219 TYR A CZ    
1773 O  OH    . TYR A 222 ? 0.39866 0.42562 0.47414 0.02069  -0.03307 0.00222  219 TYR A OH    
1774 N  N     . LEU A 223 ? 0.26300 0.24283 0.26381 -0.00247 -0.06683 0.00168  220 LEU A N     
1775 C  CA    . LEU A 223 ? 0.26636 0.23167 0.24913 -0.00751 -0.07389 0.00113  220 LEU A CA    
1776 C  C     . LEU A 223 ? 0.29800 0.27119 0.29347 -0.01216 -0.07975 0.00322  220 LEU A C     
1777 O  O     . LEU A 223 ? 0.28840 0.26996 0.29473 -0.01027 -0.07391 0.00116  220 LEU A O     
1778 C  CB    . LEU A 223 ? 0.30980 0.26126 0.27321 -0.00467 -0.06644 -0.00438 220 LEU A CB    
1779 C  CG    . LEU A 223 ? 0.34792 0.27848 0.28623 -0.00853 -0.07163 -0.00622 220 LEU A CG    
1780 C  CD1   . LEU A 223 ? 0.36700 0.28239 0.28392 -0.00343 -0.06267 -0.01031 220 LEU A CD1   
1781 C  CD2   . LEU A 223 ? 0.31898 0.25023 0.26144 -0.01203 -0.07455 -0.00721 220 LEU A CD2   
1782 N  N     . CYS A 224 ? 0.28268 0.25394 0.27761 -0.01855 -0.09151 0.00798  221 CYS A N     
1783 C  CA    . CYS A 224 ? 0.33307 0.31040 0.33851 -0.02463 -0.09852 0.01107  221 CYS A CA    
1784 C  C     . CYS A 224 ? 0.35938 0.31592 0.34038 -0.03062 -0.10475 0.00855  221 CYS A C     
1785 O  O     . CYS A 224 ? 0.35311 0.29144 0.31061 -0.03234 -0.10910 0.00742  221 CYS A O     
1786 C  CB    . CYS A 224 ? 0.36783 0.35782 0.39086 -0.02872 -0.10863 0.01931  221 CYS A CB    
1787 S  SG    . CYS A 224 ? 0.31673 0.32652 0.36441 -0.02088 -0.10193 0.02281  221 CYS A SG    
1788 N  N     . TYR A 225 ? 0.30082 0.25825 0.28556 -0.03383 -0.10511 0.00774  222 TYR A N     
1789 C  CA    . TYR A 225 ? 0.35432 0.28931 0.31394 -0.03886 -0.10982 0.00461  222 TYR A CA    
1790 C  C     . TYR A 225 ? 0.36810 0.30662 0.33667 -0.04794 -0.11937 0.00887  222 TYR A C     
1791 O  O     . TYR A 225 ? 0.34614 0.30569 0.34128 -0.04836 -0.11806 0.01288  222 TYR A O     
1792 C  CB    . TYR A 225 ? 0.31194 0.23715 0.25884 -0.03215 -0.09787 -0.00252 222 TYR A CB    
1793 C  CG    . TYR A 225 ? 0.34464 0.28681 0.31252 -0.02847 -0.08961 -0.00328 222 TYR A CG    
1794 C  CD1   . TYR A 225 ? 0.38526 0.32665 0.35613 -0.03309 -0.09219 -0.00277 222 TYR A CD1   
1795 C  CD2   . TYR A 225 ? 0.34688 0.30406 0.32967 -0.02089 -0.07958 -0.00442 222 TYR A CD2   
1796 C  CE1   . TYR A 225 ? 0.34963 0.30510 0.33754 -0.02980 -0.08464 -0.00329 222 TYR A CE1   
1797 C  CE2   . TYR A 225 ? 0.35252 0.32296 0.35153 -0.01792 -0.07261 -0.00522 222 TYR A CE2   
1798 C  CZ    . TYR A 225 ? 0.42115 0.39074 0.42239 -0.02216 -0.07501 -0.00462 222 TYR A CZ    
1799 O  OH    . TYR A 225 ? 0.32608 0.30749 0.34139 -0.01933 -0.06819 -0.00519 222 TYR A OH    
1800 N  N     . LYS A 226 ? 0.40073 0.31704 0.34543 -0.05540 -0.12874 0.00808  223 LYS A N     
1801 C  CA    . LYS A 226 ? 0.42707 0.34272 0.37627 -0.06573 -0.13921 0.01221  223 LYS A CA    
1802 C  C     . LYS A 226 ? 0.48361 0.36732 0.39807 -0.07018 -0.14336 0.00724  223 LYS A C     
1803 O  O     . LYS A 226 ? 0.46108 0.32351 0.34800 -0.06629 -0.14060 0.00215  223 LYS A O     
1804 C  CB    . LYS A 226 ? 0.51593 0.44255 0.47931 -0.07443 -0.15365 0.02117  223 LYS A CB    
1805 C  CG    . LYS A 226 ? 0.44976 0.35364 0.38531 -0.07975 -0.16478 0.02135  223 LYS A CG    
1806 C  CD    . LYS A 226 ? 0.58569 0.50338 0.53902 -0.08487 -0.17328 0.03122  223 LYS A CD    
1807 C  CE    . LYS A 226 ? 0.65327 0.54631 0.58033 -0.09287 -0.18302 0.03296  223 LYS A CE    
1808 N  NZ    . LYS A 226 ? 0.68700 0.59433 0.63484 -0.10034 -0.19215 0.04348  223 LYS A NZ    
1809 N  N     . VAL A 227 ? 0.48087 0.36032 0.39604 -0.07836 -0.14968 0.00908  224 VAL A N     
1810 C  CA    . VAL A 227 ? 0.52342 0.37070 0.40533 -0.08315 -0.15396 0.00455  224 VAL A CA    
1811 C  C     . VAL A 227 ? 0.58444 0.42917 0.46848 -0.09401 -0.16463 0.01217  224 VAL A C     
1812 O  O     . VAL A 227 ? 0.52259 0.39109 0.43613 -0.09873 -0.16806 0.01958  224 VAL A O     
1813 C  CB    . VAL A 227 ? 0.53138 0.37428 0.41089 -0.07724 -0.14231 -0.00064 224 VAL A CB    
1814 C  CG1   . VAL A 227 ? 0.51827 0.32355 0.35882 -0.07979 -0.14492 -0.00618 224 VAL A CG1   
1815 C  CG2   . VAL A 227 ? 0.49001 0.34562 0.37869 -0.06336 -0.12601 -0.00489 224 VAL A CG2   
1816 N  N     . GLU A 228 ? 0.57583 0.39127 0.42819 -0.09746 -0.16910 0.01070  225 GLU A N     
1817 C  CA    . GLU A 228 ? 0.62258 0.42912 0.47028 -0.10804 -0.17953 0.01711  225 GLU A CA    
1818 C  C     . GLU A 228 ? 0.65262 0.42645 0.46712 -0.10865 -0.17785 0.01187  225 GLU A C     
1819 O  O     . GLU A 228 ? 0.66510 0.41878 0.45456 -0.10062 -0.16961 0.00391  225 GLU A O     
1820 C  CB    . GLU A 228 ? 0.60986 0.41156 0.45094 -0.11309 -0.18938 0.02253  225 GLU A CB    
1821 C  CG    . GLU A 228 ? 0.62722 0.45970 0.50006 -0.11195 -0.19125 0.02854  225 GLU A CG    
1822 C  CD    . GLU A 228 ? 0.72926 0.55191 0.58888 -0.11415 -0.19869 0.03144  225 GLU A CD    
1823 O  OE1   . GLU A 228 ? 0.74243 0.54887 0.57897 -0.10795 -0.19408 0.02513  225 GLU A OE1   
1824 O  OE2   . GLU A 228 ? 0.70362 0.53336 0.57453 -0.12221 -0.20905 0.04021  225 GLU A OE2   
1825 N  N     . ARG A 229 ? 0.63268 0.40150 0.44744 -0.11784 -0.18533 0.01700  226 ARG A N     
1826 C  CA    . ARG A 229 ? 0.71575 0.45429 0.50105 -0.11957 -0.18503 0.01356  226 ARG A CA    
1827 C  C     . ARG A 229 ? 0.73689 0.45383 0.50087 -0.12906 -0.19714 0.01854  226 ARG A C     
1828 O  O     . ARG A 229 ? 0.76619 0.49797 0.54789 -0.13744 -0.20742 0.02703  226 ARG A O     
1829 C  CB    . ARG A 229 ? 0.77410 0.52326 0.57626 -0.12277 -0.18356 0.01537  226 ARG A CB    
1830 C  CG    . ARG A 229 ? 0.87406 0.59307 0.64732 -0.12308 -0.18169 0.01137  226 ARG A CG    
1831 C  CD    . ARG A 229 ? 0.83499 0.56686 0.62734 -0.12604 -0.17984 0.01344  226 ARG A CD    
1832 N  NE    . ARG A 229 ? 0.90220 0.65704 0.72236 -0.13671 -0.18926 0.02354  226 ARG A NE    
1833 C  CZ    . ARG A 229 ? 1.01985 0.76366 0.83168 -0.14745 -0.20036 0.02994  226 ARG A CZ    
1834 N  NH1   . ARG A 229 ? 0.97295 0.68184 0.74821 -0.14957 -0.20414 0.02724  226 ARG A NH1   
1835 N  NH2   . ARG A 229 ? 1.02624 0.79440 0.86693 -0.15602 -0.20757 0.03969  226 ARG A NH2   
1836 N  N     . LEU A 230 ? 0.80150 0.48293 0.52721 -0.12735 -0.19566 0.01364  227 LEU A N     
1837 C  CA    . LEU A 230 ? 0.88589 0.54204 0.58689 -0.13675 -0.20728 0.01800  227 LEU A CA    
1838 C  C     . LEU A 230 ? 0.93269 0.58613 0.63725 -0.14635 -0.21445 0.02301  227 LEU A C     
1839 O  O     . LEU A 230 ? 0.96542 0.60629 0.65865 -0.14307 -0.20812 0.01855  227 LEU A O     
1840 C  CB    . LEU A 230 ? 0.90274 0.52070 0.56019 -0.13054 -0.20193 0.01112  227 LEU A CB    
1841 C  CG    . LEU A 230 ? 1.00127 0.59187 0.62997 -0.13826 -0.21294 0.01476  227 LEU A CG    
1842 C  CD1   . LEU A 230 ? 0.95053 0.56184 0.60047 -0.14506 -0.22336 0.02207  227 LEU A CD1   
1843 C  CD2   . LEU A 230 ? 0.94610 0.50350 0.53536 -0.12916 -0.20417 0.00749  227 LEU A CD2   
1844 N  N     . HIS A 231 ? 1.00829 0.67354 0.72872 -0.15805 -0.22752 0.03267  228 HIS A N     
1845 C  CA    . HIS A 231 ? 1.08241 0.74649 0.80755 -0.16858 -0.23574 0.03892  228 HIS A CA    
1846 C  C     . HIS A 231 ? 1.19971 0.84843 0.91083 -0.18073 -0.25143 0.04670  228 HIS A C     
1847 O  O     . HIS A 231 ? 1.15664 0.82525 0.88900 -0.18560 -0.25902 0.05399  228 HIS A O     
1848 C  CB    . HIS A 231 ? 1.09311 0.79673 0.86284 -0.17061 -0.23455 0.04465  228 HIS A CB    
1849 C  CG    . HIS A 231 ? 1.28128 0.98487 1.05673 -0.18010 -0.24055 0.05038  228 HIS A CG    
1850 N  ND1   . HIS A 231 ? 1.27470 0.95509 1.02767 -0.17922 -0.23677 0.04536  228 HIS A ND1   
1851 C  CD2   . HIS A 231 ? 1.28010 1.00415 1.08138 -0.19049 -0.24983 0.06113  228 HIS A CD2   
1852 C  CE1   . HIS A 231 ? 1.32602 1.01213 1.09007 -0.18920 -0.24390 0.05251  228 HIS A CE1   
1853 N  NE2   . HIS A 231 ? 1.29318 1.00604 1.08681 -0.19622 -0.25178 0.06227  228 HIS A NE2   
1854 N  N     . ASN A 232 ? 1.16893 0.78182 0.84415 -0.18555 -0.25638 0.04549  229 ASN A N     
1855 C  CA    . ASN A 232 ? 1.20556 0.79775 0.86136 -0.19775 -0.27195 0.05248  229 ASN A CA    
1856 C  C     . ASN A 232 ? 1.18903 0.77608 0.83574 -0.19634 -0.27518 0.05270  229 ASN A C     
1857 O  O     . ASN A 232 ? 1.17331 0.77215 0.83426 -0.20512 -0.28706 0.06147  229 ASN A O     
1858 C  CB    . ASN A 232 ? 1.14251 0.75734 0.82760 -0.21078 -0.28432 0.06427  229 ASN A CB    
1859 C  CG    . ASN A 232 ? 1.23387 0.84957 0.92382 -0.21388 -0.28262 0.06476  229 ASN A CG    
1860 O  OD1   . ASN A 232 ? 1.28262 0.86868 0.94149 -0.21122 -0.27848 0.05832  229 ASN A OD1   
1861 N  ND2   . ASN A 232 ? 1.18772 0.83699 0.91644 -0.21936 -0.28555 0.07285  229 ASN A ND2   
1862 N  N     . ASP A 233 ? 1.26549 0.83483 0.88845 -0.18494 -0.26415 0.04328  230 ASP A N     
1863 C  CA    . ASP A 233 ? 1.33173 0.89275 0.94179 -0.18221 -0.26524 0.04218  230 ASP A CA    
1864 C  C     . ASP A 233 ? 1.26845 0.86800 0.91838 -0.18324 -0.26849 0.04811  230 ASP A C     
1865 O  O     . ASP A 233 ? 1.26119 0.85902 0.90897 -0.18833 -0.27764 0.05304  230 ASP A O     
1866 C  CB    . ASP A 233 ? 1.49012 1.01455 1.06353 -0.19195 -0.27800 0.04577  230 ASP A CB    
1867 C  CG    . ASP A 233 ? 1.62955 1.11109 1.15591 -0.18575 -0.27056 0.03751  230 ASP A CG    
1868 O  OD1   . ASP A 233 ? 1.63597 1.10890 1.14806 -0.17420 -0.25887 0.03013  230 ASP A OD1   
1869 O  OD2   . ASP A 233 ? 1.65961 1.11604 1.16327 -0.19214 -0.27603 0.03876  230 ASP A OD2   
1870 N  N     . THR A 234 ? 1.22081 0.85474 0.90699 -0.17813 -0.26073 0.04780  231 THR A N     
1871 C  CA    . THR A 234 ? 1.06842 0.74082 0.79479 -0.17761 -0.26184 0.05341  231 THR A CA    
1872 C  C     . THR A 234 ? 0.95045 0.64578 0.69768 -0.16540 -0.24669 0.04674  231 THR A C     
1873 O  O     . THR A 234 ? 0.96445 0.65731 0.70998 -0.16166 -0.23885 0.04192  231 THR A O     
1874 C  CB    . THR A 234 ? 1.08028 0.77595 0.83731 -0.18877 -0.27263 0.06495  231 THR A CB    
1875 O  OG1   . THR A 234 ? 1.24317 0.91341 0.97703 -0.20102 -0.28703 0.07080  231 THR A OG1   
1876 C  CG2   . THR A 234 ? 0.87007 0.60159 0.66489 -0.18822 -0.27474 0.07200  231 THR A CG2   
1877 N  N     . TRP A 235 ? 0.91152 0.62823 0.67769 -0.15944 -0.24303 0.04671  232 TRP A N     
1878 C  CA    . TRP A 235 ? 0.87821 0.61779 0.66531 -0.14842 -0.22977 0.04119  232 TRP A CA    
1879 C  C     . TRP A 235 ? 0.84581 0.62335 0.67698 -0.15089 -0.23038 0.04848  232 TRP A C     
1880 O  O     . TRP A 235 ? 0.89523 0.69322 0.74972 -0.15504 -0.23734 0.05696  232 TRP A O     
1881 C  CB    . TRP A 235 ? 0.78585 0.52823 0.56976 -0.14056 -0.22528 0.03764  232 TRP A CB    
1882 C  CG    . TRP A 235 ? 0.79113 0.49919 0.53387 -0.13459 -0.21949 0.02891  232 TRP A CG    
1883 C  CD1   . TRP A 235 ? 0.88715 0.57309 0.60362 -0.13584 -0.22410 0.02879  232 TRP A CD1   
1884 C  CD2   . TRP A 235 ? 0.72397 0.41638 0.44775 -0.12569 -0.20701 0.01949  232 TRP A CD2   
1885 N  NE1   . TRP A 235 ? 0.89036 0.54791 0.57260 -0.12798 -0.21451 0.02002  232 TRP A NE1   
1886 C  CE2   . TRP A 235 ? 0.79157 0.45302 0.47824 -0.12138 -0.20382 0.01437  232 TRP A CE2   
1887 C  CE3   . TRP A 235 ? 0.74279 0.44409 0.47743 -0.12074 -0.19796 0.01528  232 TRP A CE3   
1888 C  CZ2   . TRP A 235 ? 0.92696 0.56755 0.58864 -0.11158 -0.19111 0.00566  232 TRP A CZ2   
1889 C  CZ3   . TRP A 235 ? 0.75127 0.43129 0.46074 -0.11149 -0.18635 0.00642  232 TRP A CZ3   
1890 C  CH2   . TRP A 235 ? 0.76811 0.41886 0.44228 -0.10663 -0.18262 0.00192  232 TRP A CH2   
1891 N  N     . VAL A 236 ? 0.75690 0.54311 0.59898 -0.14805 -0.22269 0.04557  233 VAL A N     
1892 C  CA    . VAL A 236 ? 0.83848 0.65916 0.72073 -0.14959 -0.22127 0.05212  233 VAL A CA    
1893 C  C     . VAL A 236 ? 0.80373 0.64424 0.70371 -0.13831 -0.20815 0.04627  233 VAL A C     
1894 O  O     . VAL A 236 ? 0.74678 0.57117 0.62637 -0.13107 -0.19990 0.03670  233 VAL A O     
1895 C  CB    . VAL A 236 ? 0.82963 0.64527 0.71184 -0.15688 -0.22397 0.05493  233 VAL A CB    
1896 C  CG1   . VAL A 236 ? 0.80036 0.58790 0.65185 -0.15271 -0.21724 0.04507  233 VAL A CG1   
1897 C  CG2   . VAL A 236 ? 0.81736 0.66771 0.73947 -0.15664 -0.21938 0.06050  233 VAL A CG2   
1898 N  N     . PRO A 237 ? 0.80239 0.67668 0.73905 -0.13605 -0.20560 0.05191  234 PRO A N     
1899 C  CA    . PRO A 237 ? 0.78944 0.68203 0.74286 -0.12580 -0.19346 0.04678  234 PRO A CA    
1900 C  C     . PRO A 237 ? 0.81824 0.70662 0.76893 -0.12394 -0.18588 0.04147  234 PRO A C     
1901 O  O     . PRO A 237 ? 0.84635 0.73372 0.80057 -0.13071 -0.18888 0.04538  234 PRO A O     
1902 C  CB    . PRO A 237 ? 0.80676 0.73502 0.80032 -0.12520 -0.19289 0.05591  234 PRO A CB    
1903 C  CG    . PRO A 237 ? 0.84637 0.77444 0.84251 -0.13383 -0.20492 0.06518  234 PRO A CG    
1904 C  CD    . PRO A 237 ? 0.86930 0.76408 0.83072 -0.14176 -0.21376 0.06319  234 PRO A CD    
1905 N  N     . LEU A 238 ? 0.76607 0.65123 0.70975 -0.11483 -0.17630 0.03274  235 LEU A N     
1906 C  CA    . LEU A 238 ? 0.79525 0.68171 0.74207 -0.11130 -0.16771 0.02787  235 LEU A CA    
1907 C  C     . LEU A 238 ? 0.88026 0.79853 0.86014 -0.10502 -0.16016 0.02949  235 LEU A C     
1908 O  O     . LEU A 238 ? 0.96371 0.88478 0.94238 -0.09700 -0.15470 0.02427  235 LEU A O     
1909 C  CB    . LEU A 238 ? 0.81736 0.67522 0.73099 -0.10515 -0.16215 0.01716  235 LEU A CB    
1910 C  CG    . LEU A 238 ? 0.79528 0.64630 0.70508 -0.10301 -0.15516 0.01248  235 LEU A CG    
1911 C  CD1   . LEU A 238 ? 0.87935 0.70776 0.76959 -0.11041 -0.16049 0.01393  235 LEU A CD1   
1912 C  CD2   . LEU A 238 ? 0.74623 0.58381 0.63812 -0.09190 -0.14492 0.00261  235 LEU A CD2   
1913 N  N     . ASN A 239 ? 0.90675 0.84838 0.91550 -0.10840 -0.15940 0.03707  236 ASN A N     
1914 C  CA    . ASN A 239 ? 1.01897 0.99181 1.06066 -0.10243 -0.15208 0.04060  236 ASN A CA    
1915 C  C     . ASN A 239 ? 0.99910 0.97534 1.04249 -0.09320 -0.13982 0.03344  236 ASN A C     
1916 O  O     . ASN A 239 ? 0.94703 0.94607 1.01328 -0.08545 -0.13057 0.03525  236 ASN A O     
1917 C  CB    . ASN A 239 ? 1.08015 1.07423 1.14905 -0.10759 -0.15244 0.05062  236 ASN A CB    
1918 C  CG    . ASN A 239 ? 1.12743 1.10877 1.18667 -0.11485 -0.15432 0.05085  236 ASN A CG    
1919 O  OD1   . ASN A 239 ? 1.12071 1.09712 1.17544 -0.11236 -0.14774 0.04558  236 ASN A OD1   
1920 N  ND2   . ASN A 239 ? 1.15044 1.12534 1.20573 -0.12407 -0.16379 0.05725  236 ASN A ND2   
1921 N  N     . GLN A 240 ? 0.84062 0.79373 0.85826 -0.09046 -0.13540 0.02550  237 GLN A N     
1922 C  CA    . GLN A 240 ? 0.86129 0.81857 0.88099 -0.07982 -0.12051 0.02007  237 GLN A CA    
1923 C  C     . GLN A 240 ? 0.86375 0.82390 0.88038 -0.06796 -0.11131 0.01451  237 GLN A C     
1924 O  O     . GLN A 240 ? 0.84683 0.82346 0.87905 -0.05998 -0.10062 0.01368  237 GLN A O     
1925 C  CB    . GLN A 240 ? 0.87304 0.80576 0.86846 -0.08074 -0.11919 0.01473  237 GLN A CB    
1926 C  CG    . GLN A 240 ? 1.02852 0.96123 1.03040 -0.09090 -0.12458 0.02005  237 GLN A CG    
1927 C  CD    . GLN A 240 ? 1.04604 0.95432 1.02644 -0.10299 -0.13890 0.02120  237 GLN A CD    
1928 O  OE1   . GLN A 240 ? 1.11772 0.99732 1.06734 -0.10150 -0.13969 0.01456  237 GLN A OE1   
1929 N  NE2   . GLN A 240 ? 1.07340 0.99307 1.06918 -0.11307 -0.14810 0.03012  237 GLN A NE2   
1930 N  N     . HIS A 241 ? 0.64388 0.58721 0.63949 -0.06695 -0.11518 0.01082  238 HIS A N     
1931 C  CA    . HIS A 241 ? 0.51488 0.45643 0.50296 -0.05602 -0.10574 0.00498  238 HIS A CA    
1932 C  C     . HIS A 241 ? 0.49440 0.44451 0.48925 -0.05579 -0.11013 0.00796  238 HIS A C     
1933 O  O     . HIS A 241 ? 0.42012 0.35352 0.39467 -0.05738 -0.11581 0.00626  238 HIS A O     
1934 C  CB    . HIS A 241 ? 0.53007 0.44375 0.48657 -0.05326 -0.10385 -0.00188 238 HIS A CB    
1935 C  CG    . HIS A 241 ? 0.61038 0.51492 0.56012 -0.05254 -0.09938 -0.00448 238 HIS A CG    
1936 N  ND1   . HIS A 241 ? 0.63707 0.55640 0.60226 -0.04625 -0.08931 -0.00525 238 HIS A ND1   
1937 C  CD2   . HIS A 241 ? 0.63652 0.51738 0.56474 -0.05755 -0.10410 -0.00619 238 HIS A CD2   
1938 C  CE1   . HIS A 241 ? 0.53908 0.44528 0.49346 -0.04711 -0.08798 -0.00704 238 HIS A CE1   
1939 N  NE2   . HIS A 241 ? 0.55495 0.43757 0.48708 -0.05375 -0.09658 -0.00770 238 HIS A NE2   
1940 N  N     . ARG A 242 ? 0.38895 0.36399 0.41126 -0.05334 -0.10701 0.01254  239 ARG A N     
1941 C  CA    . ARG A 242 ? 0.41247 0.39837 0.44552 -0.05280 -0.11109 0.01672  239 ARG A CA    
1942 C  C     . ARG A 242 ? 0.33470 0.33914 0.38636 -0.04315 -0.09940 0.01602  239 ARG A C     
1943 O  O     . ARG A 242 ? 0.41404 0.43238 0.48268 -0.04120 -0.09300 0.01743  239 ARG A O     
1944 C  CB    . ARG A 242 ? 0.43187 0.42928 0.48202 -0.06245 -0.12295 0.02596  239 ARG A CB    
1945 C  CG    . ARG A 242 ? 0.53906 0.54154 0.59422 -0.06436 -0.13165 0.03115  239 ARG A CG    
1946 C  CD    . ARG A 242 ? 0.60353 0.61865 0.67755 -0.07463 -0.14407 0.04135  239 ARG A CD    
1947 N  NE    . ARG A 242 ? 0.65055 0.69395 0.75843 -0.07059 -0.13723 0.04770  239 ARG A NE    
1948 C  CZ    . ARG A 242 ? 0.60773 0.66528 0.73467 -0.07445 -0.13925 0.05669  239 ARG A CZ    
1949 N  NH1   . ARG A 242 ? 0.62969 0.67754 0.74778 -0.08365 -0.14967 0.06110  239 ARG A NH1   
1950 N  NH2   . ARG A 242 ? 0.72323 0.80425 0.87787 -0.06866 -0.13030 0.06156  239 ARG A NH2   
1951 N  N     . GLY A 243 ? 0.32681 0.32958 0.37330 -0.03734 -0.09639 0.01371  240 GLY A N     
1952 C  CA    . GLY A 243 ? 0.21848 0.23527 0.27925 -0.02871 -0.08574 0.01247  240 GLY A CA    
1953 C  C     . GLY A 243 ? 0.28755 0.29865 0.33875 -0.02382 -0.08386 0.01004  240 GLY A C     
1954 O  O     . GLY A 243 ? 0.29928 0.29902 0.33664 -0.02722 -0.09158 0.01093  240 GLY A O     
1955 N  N     . PHE A 244 ? 0.25336 0.27147 0.31100 -0.01635 -0.07391 0.00727  241 PHE A N     
1956 C  CA    . PHE A 244 ? 0.27670 0.28900 0.32500 -0.01188 -0.07104 0.00490  241 PHE A CA    
1957 C  C     . PHE A 244 ? 0.31046 0.32288 0.35661 -0.00561 -0.06010 -0.00048 241 PHE A C     
1958 O  O     . PHE A 244 ? 0.30308 0.32271 0.35814 -0.00401 -0.05483 -0.00174 241 PHE A O     
1959 C  CB    . PHE A 244 ? 0.27335 0.29658 0.33610 -0.01015 -0.07316 0.00995  241 PHE A CB    
1960 C  CG    . PHE A 244 ? 0.27272 0.31043 0.35413 -0.00460 -0.06482 0.01042  241 PHE A CG    
1961 C  CD1   . PHE A 244 ? 0.28209 0.33313 0.38194 -0.00541 -0.06442 0.01442  241 PHE A CD1   
1962 C  CD2   . PHE A 244 ? 0.32059 0.35738 0.39993 0.00121  -0.05710 0.00701  241 PHE A CD2   
1963 C  CE1   . PHE A 244 ? 0.34040 0.40196 0.45422 0.00026  -0.05585 0.01451  241 PHE A CE1   
1964 C  CE2   . PHE A 244 ? 0.31348 0.36013 0.40651 0.00592  -0.04982 0.00698  241 PHE A CE2   
1965 C  CZ    . PHE A 244 ? 0.32268 0.38085 0.43184 0.00584  -0.04887 0.01045  241 PHE A CZ    
1966 N  N     . LEU A 245 ? 0.30524 0.30959 0.33930 -0.00246 -0.05704 -0.00309 242 LEU A N     
1967 C  CA    . LEU A 245 ? 0.27791 0.28355 0.31132 0.00287  -0.04766 -0.00702 242 LEU A CA    
1968 C  C     . LEU A 245 ? 0.32021 0.32339 0.34940 0.00549  -0.04582 -0.00667 242 LEU A C     
1969 O  O     . LEU A 245 ? 0.29069 0.28973 0.31541 0.00352  -0.05167 -0.00379 242 LEU A O     
1970 C  CB    . LEU A 245 ? 0.27956 0.27499 0.29892 0.00371  -0.04434 -0.01100 242 LEU A CB    
1971 C  CG    . LEU A 245 ? 0.33376 0.31180 0.33158 0.00189  -0.04805 -0.01194 242 LEU A CG    
1972 C  CD1   . LEU A 245 ? 0.28991 0.26160 0.27705 0.00565  -0.04348 -0.01296 242 LEU A CD1   
1973 C  CD2   . LEU A 245 ? 0.35025 0.31887 0.33754 0.00198  -0.04630 -0.01487 242 LEU A CD2   
1974 N  N     . ARG A 246 ? 0.25021 0.25544 0.28022 0.00943  -0.03819 -0.00919 243 ARG A N     
1975 C  CA    . ARG A 246 ? 0.27455 0.27751 0.30091 0.01153  -0.03560 -0.00862 243 ARG A CA    
1976 C  C     . ARG A 246 ? 0.26413 0.26376 0.28326 0.01430  -0.02840 -0.01139 243 ARG A C     
1977 O  O     . ARG A 246 ? 0.27691 0.27762 0.29621 0.01527  -0.02532 -0.01365 243 ARG A O     
1978 C  CB    . ARG A 246 ? 0.27881 0.29121 0.31974 0.01310  -0.03418 -0.00687 243 ARG A CB    
1979 C  CG    . ARG A 246 ? 0.33898 0.35935 0.39026 0.01480  -0.02889 -0.00913 243 ARG A CG    
1980 C  CD    . ARG A 246 ? 0.33220 0.35566 0.38980 0.01692  -0.02516 -0.00892 243 ARG A CD    
1981 N  NE    . ARG A 246 ? 0.29635 0.31428 0.34581 0.01727  -0.02319 -0.00879 243 ARG A NE    
1982 C  CZ    . ARG A 246 ? 0.35848 0.37589 0.41043 0.01813  -0.02165 -0.00753 243 ARG A CZ    
1983 N  NH1   . ARG A 246 ? 0.36870 0.38938 0.42975 0.01944  -0.02164 -0.00667 243 ARG A NH1   
1984 N  NH2   . ARG A 246 ? 0.34112 0.35383 0.38578 0.01789  -0.01948 -0.00690 243 ARG A NH2   
1985 N  N     . ASN A 247 ? 0.26419 0.26023 0.27765 0.01563  -0.02569 -0.01044 244 ASN A N     
1986 C  CA    . ASN A 247 ? 0.24571 0.24059 0.25466 0.01830  -0.01839 -0.01162 244 ASN A CA    
1987 C  C     . ASN A 247 ? 0.25542 0.26137 0.27839 0.01924  -0.01434 -0.01260 244 ASN A C     
1988 O  O     . ASN A 247 ? 0.22905 0.24129 0.26273 0.01831  -0.01591 -0.01228 244 ASN A O     
1989 C  CB    . ASN A 247 ? 0.23597 0.22577 0.23744 0.01894  -0.01613 -0.00944 244 ASN A CB    
1990 C  CG    . ASN A 247 ? 0.31105 0.30742 0.32370 0.01822  -0.01644 -0.00757 244 ASN A CG    
1991 O  OD1   . ASN A 247 ? 0.27068 0.26880 0.28901 0.01701  -0.02164 -0.00635 244 ASN A OD1   
1992 N  ND2   . ASN A 247 ? 0.27326 0.27331 0.28975 0.01900  -0.01081 -0.00692 244 ASN A ND2   
1993 N  N     . GLN A 248 ? 0.23582 0.24328 0.25787 0.02132  -0.00908 -0.01346 245 GLN A N     
1994 C  CA    . GLN A 248 ? 0.22398 0.24113 0.25767 0.02160  -0.00602 -0.01381 245 GLN A CA    
1995 C  C     . GLN A 248 ? 0.22557 0.24551 0.26162 0.02173  -0.00182 -0.01150 245 GLN A C     
1996 O  O     . GLN A 248 ? 0.24432 0.26178 0.27432 0.02387  0.00267  -0.00999 245 GLN A O     
1997 C  CB    . GLN A 248 ? 0.28497 0.30358 0.31835 0.02361  -0.00378 -0.01509 245 GLN A CB    
1998 C  CG    . GLN A 248 ? 0.26284 0.27802 0.29364 0.02272  -0.00797 -0.01701 245 GLN A CG    
1999 C  CD    . GLN A 248 ? 0.37277 0.39516 0.41447 0.02065  -0.01050 -0.01775 245 GLN A CD    
2000 O  OE1   . GLN A 248 ? 0.39949 0.42835 0.44883 0.02050  -0.00868 -0.01784 245 GLN A OE1   
2001 N  NE2   . GLN A 248 ? 0.47379 0.49451 0.51566 0.01884  -0.01469 -0.01789 245 GLN A NE2   
2002 N  N     . ALA A 249 ? 0.21166 0.23585 0.25586 0.01950  -0.00288 -0.01094 246 ALA A N     
2003 C  CA    . ALA A 249 ? 0.24546 0.27197 0.29259 0.01828  0.00021  -0.00830 246 ALA A CA    
2004 C  C     . ALA A 249 ? 0.26322 0.29778 0.31706 0.01857  0.00390  -0.00707 246 ALA A C     
2005 O  O     . ALA A 249 ? 0.22999 0.26874 0.28808 0.01901  0.00285  -0.00874 246 ALA A O     
2006 C  CB    . ALA A 249 ? 0.28720 0.31378 0.33987 0.01554  -0.00240 -0.00834 246 ALA A CB    
2007 N  N     . PRO A 250 ? 0.24331 0.28088 0.29911 0.01820  0.00812  -0.00341 247 PRO A N     
2008 C  CA    . PRO A 250 ? 0.22110 0.26862 0.28596 0.01861  0.01148  -0.00078 247 PRO A CA    
2009 C  C     . PRO A 250 ? 0.23379 0.28785 0.30885 0.01449  0.00733  -0.00132 247 PRO A C     
2010 O  O     . PRO A 250 ? 0.20249 0.25313 0.27788 0.01076  0.00371  -0.00258 247 PRO A O     
2011 C  CB    . PRO A 250 ? 0.20730 0.25708 0.27346 0.01809  0.01667  0.00419  247 PRO A CB    
2012 C  CG    . PRO A 250 ? 0.31691 0.35494 0.36923 0.01957  0.01728  0.00337  247 PRO A CG    
2013 C  CD    . PRO A 250 ? 0.33221 0.36469 0.38222 0.01765  0.01036  -0.00066 247 PRO A CD    
2014 N  N     . ASN A 251 ? 0.16553 0.22791 0.24783 0.01542  0.00796  -0.00004 248 ASN A N     
2015 C  CA    . ASN A 251 ? 0.20191 0.26993 0.29226 0.01125  0.00341  -0.00012 248 ASN A CA    
2016 C  C     . ASN A 251 ? 0.25550 0.33389 0.35425 0.01357  0.00515  0.00315  248 ASN A C     
2017 O  O     . ASN A 251 ? 0.21716 0.29426 0.31208 0.01904  0.00786  0.00214  248 ASN A O     
2018 C  CB    . ASN A 251 ? 0.20149 0.26266 0.28626 0.01061  -0.00110 -0.00540 248 ASN A CB    
2019 C  CG    . ASN A 251 ? 0.26420 0.32764 0.35316 0.00603  -0.00579 -0.00593 248 ASN A CG    
2020 O  OD1   . ASN A 251 ? 0.22895 0.29970 0.32373 0.00577  -0.00700 -0.00407 248 ASN A OD1   
2021 N  ND2   . ASN A 251 ? 0.23799 0.29401 0.32297 0.00253  -0.00856 -0.00819 248 ASN A ND2   
2022 N  N     . ILE A 252 ? 0.21323 0.30151 0.32346 0.00940  0.00335  0.00760  249 ILE A N     
2023 C  CA    . ILE A 252 ? 0.22220 0.32268 0.34331 0.01206  0.00519  0.01242  249 ILE A CA    
2024 C  C     . ILE A 252 ? 0.26351 0.36309 0.38250 0.01441  0.00191  0.00949  249 ILE A C     
2025 O  O     . ILE A 252 ? 0.26494 0.37150 0.38962 0.01924  0.00454  0.01258  249 ILE A O     
2026 C  CB    . ILE A 252 ? 0.27756 0.39018 0.41325 0.00573  0.00223  0.01878  249 ILE A CB    
2027 C  CG1   . ILE A 252 ? 0.31627 0.42559 0.45074 -0.00161 -0.00703 0.01621  249 ILE A CG1   
2028 C  CG2   . ILE A 252 ? 0.35377 0.46731 0.49189 0.00300  0.00595  0.02245  249 ILE A CG2   
2029 C  CD1   . ILE A 252 ? 0.34626 0.46756 0.49483 -0.00864 -0.01224 0.02282  249 ILE A CD1   
2030 N  N     . HIS A 253 ? 0.21549 0.30624 0.32624 0.01159  -0.00316 0.00400  250 HIS A N     
2031 C  CA    . HIS A 253 ? 0.22951 0.31782 0.33639 0.01371  -0.00570 0.00112  250 HIS A CA    
2032 C  C     . HIS A 253 ? 0.28747 0.36630 0.38358 0.01861  -0.00281 -0.00324 250 HIS A C     
2033 O  O     . HIS A 253 ? 0.30210 0.37780 0.39421 0.02011  -0.00457 -0.00559 250 HIS A O     
2034 C  CB    . HIS A 253 ? 0.29961 0.38351 0.40308 0.00789  -0.01228 -0.00179 250 HIS A CB    
2035 C  CG    . HIS A 253 ? 0.28806 0.37889 0.39974 0.00161  -0.01716 0.00224  250 HIS A CG    
2036 N  ND1   . HIS A 253 ? 0.30230 0.40591 0.42612 0.00182  -0.01832 0.00829  250 HIS A ND1   
2037 C  CD2   . HIS A 253 ? 0.34826 0.43448 0.45770 -0.00537 -0.02163 0.00158  250 HIS A CD2   
2038 C  CE1   . HIS A 253 ? 0.33562 0.44325 0.46515 -0.00569 -0.02420 0.01147  250 HIS A CE1   
2039 N  NE2   . HIS A 253 ? 0.42275 0.51871 0.54244 -0.01034 -0.02630 0.00713  250 HIS A NE2   
2040 N  N     . GLY A 254 ? 0.23881 0.31242 0.32957 0.02044  0.00093  -0.00400 251 GLY A N     
2041 C  CA    . GLY A 254 ? 0.24068 0.30525 0.32111 0.02438  0.00278  -0.00717 251 GLY A CA    
2042 C  C     . GLY A 254 ? 0.28070 0.34461 0.35859 0.02941  0.00896  -0.00456 251 GLY A C     
2043 O  O     . GLY A 254 ? 0.20979 0.27956 0.29280 0.03327  0.01221  -0.00133 251 GLY A O     
2044 N  N     . PHE A 255 ? 0.24838 0.30484 0.31802 0.02976  0.01091  -0.00548 252 PHE A N     
2045 C  CA    . PHE A 255 ? 0.23476 0.28871 0.29948 0.03430  0.01761  -0.00288 252 PHE A CA    
2046 C  C     . PHE A 255 ? 0.24963 0.31063 0.32188 0.03186  0.02019  0.00130  252 PHE A C     
2047 O  O     . PHE A 255 ? 0.26231 0.31941 0.33174 0.02790  0.01769  0.00024  252 PHE A O     
2048 C  CB    . PHE A 255 ? 0.26231 0.30177 0.31064 0.03573  0.01762  -0.00609 252 PHE A CB    
2049 C  CG    . PHE A 255 ? 0.32338 0.35520 0.36417 0.03704  0.01459  -0.00966 252 PHE A CG    
2050 C  CD1   . PHE A 255 ? 0.34210 0.36895 0.37663 0.04256  0.01867  -0.00938 252 PHE A CD1   
2051 C  CD2   . PHE A 255 ? 0.32881 0.35830 0.36916 0.03292  0.00814  -0.01279 252 PHE A CD2   
2052 C  CE1   . PHE A 255 ? 0.38959 0.40814 0.41656 0.04305  0.01553  -0.01241 252 PHE A CE1   
2053 C  CE2   . PHE A 255 ? 0.32864 0.35185 0.36312 0.03333  0.00540  -0.01527 252 PHE A CE2   
2054 C  CZ    . PHE A 255 ? 0.26931 0.28653 0.29664 0.03794  0.00867  -0.01520 252 PHE A CZ    
2055 N  N     . PRO A 256 ? 0.25393 0.32563 0.33664 0.03398  0.02510  0.00668  253 PRO A N     
2056 C  CA    . PRO A 256 ? 0.22837 0.30831 0.32052 0.03018  0.02685  0.01154  253 PRO A CA    
2057 C  C     . PRO A 256 ? 0.27122 0.34226 0.35264 0.03042  0.03069  0.01171  253 PRO A C     
2058 O  O     . PRO A 256 ? 0.26868 0.34216 0.35444 0.02537  0.02955  0.01394  253 PRO A O     
2059 C  CB    . PRO A 256 ? 0.28847 0.38192 0.39386 0.03412  0.03273  0.01820  253 PRO A CB    
2060 C  CG    . PRO A 256 ? 0.30936 0.40407 0.41624 0.03740  0.03013  0.01631  253 PRO A CG    
2061 C  CD    . PRO A 256 ? 0.25588 0.33394 0.34444 0.03959  0.02874  0.00939  253 PRO A CD    
2062 N  N     . LYS A 257 ? 0.25672 0.31597 0.32276 0.03579  0.03481  0.00959  254 LYS A N     
2063 C  CA    . LYS A 257 ? 0.26551 0.31413 0.31834 0.03586  0.03756  0.00964  254 LYS A CA    
2064 C  C     . LYS A 257 ? 0.27545 0.30990 0.31354 0.03450  0.03125  0.00394  254 LYS A C     
2065 O  O     . LYS A 257 ? 0.29879 0.32166 0.32231 0.03531  0.03255  0.00354  254 LYS A O     
2066 C  CB    . LYS A 257 ? 0.31497 0.35969 0.35950 0.04282  0.04799  0.01291  254 LYS A CB    
2067 C  CG    . LYS A 257 ? 0.34406 0.40515 0.40585 0.04537  0.05534  0.01993  254 LYS A CG    
2068 C  CD    . LYS A 257 ? 0.51768 0.57393 0.57020 0.05287  0.06759  0.02383  254 LYS A CD    
2069 C  CE    . LYS A 257 ? 0.56047 0.63074 0.62761 0.05138  0.07433  0.03208  254 LYS A CE    
2070 N  NZ    . LYS A 257 ? 0.63149 0.72163 0.72387 0.04546  0.06879  0.03593  254 LYS A NZ    
2071 N  N     . GLY A 258 ? 0.25850 0.29401 0.30041 0.03221  0.02432  0.00016  255 GLY A N     
2072 C  CA    . GLY A 258 ? 0.26115 0.28633 0.29303 0.03056  0.01811  -0.00409 255 GLY A CA    
2073 C  C     . GLY A 258 ? 0.26051 0.27483 0.27854 0.03444  0.01880  -0.00658 255 GLY A C     
2074 O  O     . GLY A 258 ? 0.25567 0.26755 0.26859 0.03943  0.02523  -0.00531 255 GLY A O     
2075 N  N     . ARG A 259 ? 0.29415 0.30128 0.30591 0.03213  0.01212  -0.00983 256 ARG A N     
2076 C  CA    . ARG A 259 ? 0.27580 0.26954 0.27172 0.03413  0.01109  -0.01214 256 ARG A CA    
2077 C  C     . ARG A 259 ? 0.26602 0.25067 0.25268 0.03031  0.00413  -0.01315 256 ARG A C     
2078 O  O     . ARG A 259 ? 0.26299 0.25253 0.25812 0.02667  -0.00216 -0.01394 256 ARG A O     
2079 C  CB    . ARG A 259 ? 0.24671 0.24232 0.24655 0.03473  0.00899  -0.01434 256 ARG A CB    
2080 C  CG    . ARG A 259 ? 0.26065 0.24010 0.24214 0.03727  0.00922  -0.01638 256 ARG A CG    
2081 C  CD    . ARG A 259 ? 0.33776 0.31843 0.32241 0.03960  0.00989  -0.01757 256 ARG A CD    
2082 N  NE    . ARG A 259 ? 0.27732 0.24020 0.24271 0.04249  0.01102  -0.01939 256 ARG A NE    
2083 C  CZ    . ARG A 259 ? 0.41755 0.37215 0.37219 0.04906  0.01911  -0.01855 256 ARG A CZ    
2084 N  NH1   . ARG A 259 ? 0.41834 0.38262 0.38115 0.05308  0.02677  -0.01524 256 ARG A NH1   
2085 N  NH2   . ARG A 259 ? 0.38175 0.31732 0.31673 0.05171  0.01987  -0.02074 256 ARG A NH2   
2086 N  N     . HIS A 260 ? 0.27537 0.24677 0.24458 0.03134  0.00538  -0.01262 257 HIS A N     
2087 C  CA    . HIS A 260 ? 0.28446 0.24773 0.24504 0.02742  -0.00194 -0.01242 257 HIS A CA    
2088 C  C     . HIS A 260 ? 0.32883 0.28629 0.28526 0.02425  -0.01017 -0.01454 257 HIS A C     
2089 O  O     . HIS A 260 ? 0.27106 0.22430 0.22327 0.02564  -0.00925 -0.01663 257 HIS A O     
2090 C  CB    . HIS A 260 ? 0.32335 0.27181 0.26325 0.02916  0.00138  -0.01121 257 HIS A CB    
2091 C  CG    . HIS A 260 ? 0.34822 0.30278 0.29285 0.03117  0.00892  -0.00801 257 HIS A CG    
2092 N  ND1   . HIS A 260 ? 0.35140 0.29466 0.27966 0.03211  0.01212  -0.00595 257 HIS A ND1   
2093 C  CD2   . HIS A 260 ? 0.40415 0.37441 0.36763 0.03163  0.01338  -0.00608 257 HIS A CD2   
2094 C  CE1   . HIS A 260 ? 0.40653 0.35920 0.34455 0.03321  0.01886  -0.00262 257 HIS A CE1   
2095 N  NE2   . HIS A 260 ? 0.34318 0.31230 0.30284 0.03259  0.01926  -0.00261 257 HIS A NE2   
2096 N  N     . ALA A 261 ? 0.26610 0.22349 0.22434 0.01988  -0.01839 -0.01331 258 ALA A N     
2097 C  CA    . ALA A 261 ? 0.28538 0.24083 0.24428 0.01578  -0.02697 -0.01392 258 ALA A CA    
2098 C  C     . ALA A 261 ? 0.34013 0.27771 0.27772 0.01516  -0.02897 -0.01588 258 ALA A C     
2099 O  O     . ALA A 261 ? 0.31569 0.25225 0.25457 0.01354  -0.03172 -0.01737 258 ALA A O     
2100 C  CB    . ALA A 261 ? 0.25406 0.21167 0.21731 0.01174  -0.03534 -0.01087 258 ALA A CB    
2101 N  N     . ALA A 262 ? 0.31042 0.23197 0.22651 0.01629  -0.02753 -0.01586 259 ALA A N     
2102 C  CA    . ALA A 262 ? 0.33017 0.23055 0.22177 0.01577  -0.02937 -0.01813 259 ALA A CA    
2103 C  C     . ALA A 262 ? 0.41049 0.30923 0.30129 0.02057  -0.02189 -0.02087 259 ALA A C     
2104 O  O     . ALA A 262 ? 0.39178 0.27855 0.27166 0.01869  -0.02571 -0.02288 259 ALA A O     
2105 C  CB    . ALA A 262 ? 0.31651 0.19856 0.18292 0.01749  -0.02677 -0.01782 259 ALA A CB    
2106 N  N     . LEU A 263 ? 0.35311 0.26350 0.25555 0.02651  -0.01170 -0.02046 260 LEU A N     
2107 C  CA    . LEU A 263 ? 0.37678 0.28748 0.28084 0.03158  -0.00497 -0.02209 260 LEU A CA    
2108 C  C     . LEU A 263 ? 0.34985 0.27139 0.27017 0.02836  -0.01016 -0.02286 260 LEU A C     
2109 O  O     . LEU A 263 ? 0.36696 0.28041 0.28069 0.02956  -0.00988 -0.02466 260 LEU A O     
2110 C  CB    . LEU A 263 ? 0.35311 0.27626 0.26868 0.03793  0.00600  -0.02018 260 LEU A CB    
2111 C  CG    . LEU A 263 ? 0.40727 0.32062 0.30754 0.04218  0.01370  -0.01868 260 LEU A CG    
2112 C  CD1   . LEU A 263 ? 0.41903 0.34480 0.33170 0.04898  0.02526  -0.01609 260 LEU A CD1   
2113 C  CD2   . LEU A 263 ? 0.43381 0.32021 0.30314 0.04379  0.01390  -0.02108 260 LEU A CD2   
2114 N  N     . CYS A 264 ? 0.32599 0.26471 0.26662 0.02471  -0.01423 -0.02136 261 CYS A N     
2115 C  CA    . CYS A 264 ? 0.27901 0.22738 0.23391 0.02175  -0.01841 -0.02176 261 CYS A CA    
2116 C  C     . CYS A 264 ? 0.36555 0.30197 0.30989 0.01630  -0.02700 -0.02234 261 CYS A C     
2117 O  O     . CYS A 264 ? 0.34388 0.28002 0.29083 0.01492  -0.02873 -0.02316 261 CYS A O     
2118 C  CB    . CYS A 264 ? 0.30157 0.26771 0.27719 0.01934  -0.02053 -0.01999 261 CYS A CB    
2119 S  SG    . CYS A 264 ? 0.30953 0.28991 0.29909 0.02348  -0.01256 -0.01903 261 CYS A SG    
2120 N  N     . PHE A 265 ? 0.31102 0.23746 0.24346 0.01250  -0.03315 -0.02140 262 PHE A N     
2121 C  CA    . PHE A 265 ? 0.39247 0.30539 0.31241 0.00616  -0.04269 -0.02135 262 PHE A CA    
2122 C  C     . PHE A 265 ? 0.43381 0.32586 0.33149 0.00822  -0.04025 -0.02443 262 PHE A C     
2123 O  O     . PHE A 265 ? 0.40399 0.29044 0.29942 0.00447  -0.04490 -0.02501 262 PHE A O     
2124 C  CB    . PHE A 265 ? 0.39896 0.30478 0.30920 0.00203  -0.04991 -0.01923 262 PHE A CB    
2125 C  CG    . PHE A 265 ? 0.42235 0.30813 0.31181 -0.00462 -0.06002 -0.01924 262 PHE A CG    
2126 C  CD1   . PHE A 265 ? 0.48292 0.37265 0.38117 -0.01203 -0.06965 -0.01713 262 PHE A CD1   
2127 C  CD2   . PHE A 265 ? 0.49317 0.35563 0.35366 -0.00397 -0.06018 -0.02088 262 PHE A CD2   
2128 C  CE1   . PHE A 265 ? 0.46406 0.33474 0.34293 -0.01964 -0.08052 -0.01656 262 PHE A CE1   
2129 C  CE2   . PHE A 265 ? 0.59619 0.43748 0.43462 -0.01103 -0.07067 -0.02099 262 PHE A CE2   
2130 C  CZ    . PHE A 265 ? 0.51676 0.36244 0.36492 -0.01934 -0.08147 -0.01875 262 PHE A CZ    
2131 N  N     . LEU A 266 ? 0.40086 0.28078 0.28187 0.01461  -0.03219 -0.02612 263 LEU A N     
2132 C  CA    . LEU A 266 ? 0.43205 0.29042 0.29065 0.01830  -0.02818 -0.02902 263 LEU A CA    
2133 C  C     . LEU A 266 ? 0.44175 0.30786 0.31235 0.02189  -0.02351 -0.02981 263 LEU A C     
2134 O  O     . LEU A 266 ? 0.43495 0.28395 0.29036 0.02214  -0.02420 -0.03176 263 LEU A O     
2135 C  CB    . LEU A 266 ? 0.40942 0.25613 0.25086 0.02620  -0.01791 -0.02988 263 LEU A CB    
2136 C  CG    . LEU A 266 ? 0.45642 0.28639 0.27559 0.02356  -0.02151 -0.02973 263 LEU A CG    
2137 C  CD1   . LEU A 266 ? 0.50513 0.32645 0.31033 0.03269  -0.00857 -0.03003 263 LEU A CD1   
2138 C  CD2   . LEU A 266 ? 0.43724 0.24116 0.23042 0.01712  -0.03141 -0.03176 263 LEU A CD2   
2139 N  N     . ASP A 267 ? 0.39113 0.28075 0.28666 0.02486  -0.01871 -0.02827 264 ASP A N     
2140 C  CA    . ASP A 267 ? 0.38625 0.28485 0.29440 0.02771  -0.01532 -0.02841 264 ASP A CA    
2141 C  C     . ASP A 267 ? 0.42443 0.32084 0.33476 0.02076  -0.02378 -0.02855 264 ASP A C     
2142 O  O     . ASP A 267 ? 0.40381 0.29544 0.31218 0.02256  -0.02218 -0.02932 264 ASP A O     
2143 C  CB    . ASP A 267 ? 0.34438 0.26816 0.27821 0.02962  -0.01154 -0.02647 264 ASP A CB    
2144 C  CG    . ASP A 267 ? 0.38931 0.31828 0.32501 0.03644  -0.00239 -0.02534 264 ASP A CG    
2145 O  OD1   . ASP A 267 ? 0.40937 0.32396 0.32811 0.04177  0.00348  -0.02590 264 ASP A OD1   
2146 O  OD2   . ASP A 267 ? 0.34182 0.28899 0.29590 0.03637  -0.00077 -0.02358 264 ASP A OD2   
2147 N  N     . LEU A 268 ? 0.34240 0.24354 0.25851 0.01289  -0.03262 -0.02706 265 LEU A N     
2148 C  CA    . LEU A 268 ? 0.38504 0.28779 0.30728 0.00577  -0.04027 -0.02590 265 LEU A CA    
2149 C  C     . LEU A 268 ? 0.41906 0.29710 0.31809 0.00209  -0.04538 -0.02738 265 LEU A C     
2150 O  O     . LEU A 268 ? 0.40992 0.28600 0.31120 -0.00142 -0.04838 -0.02692 265 LEU A O     
2151 C  CB    . LEU A 268 ? 0.35113 0.26624 0.28692 -0.00121 -0.04812 -0.02277 265 LEU A CB    
2152 C  CG    . LEU A 268 ? 0.40546 0.34393 0.36485 0.00092  -0.04466 -0.02101 265 LEU A CG    
2153 C  CD1   . LEU A 268 ? 0.39586 0.34248 0.36531 -0.00535 -0.05270 -0.01742 265 LEU A CD1   
2154 C  CD2   . LEU A 268 ? 0.39920 0.34971 0.37320 0.00260  -0.04063 -0.02098 265 LEU A CD2   
2155 N  N     . ILE A 269 ? 0.45623 0.31383 0.33150 0.00221  -0.04681 -0.02900 266 ILE A N     
2156 C  CA    . ILE A 269 ? 0.50788 0.33940 0.35866 -0.00366 -0.05437 -0.03025 266 ILE A CA    
2157 C  C     . ILE A 269 ? 0.52467 0.34220 0.36489 0.00010  -0.04993 -0.03249 266 ILE A C     
2158 O  O     . ILE A 269 ? 0.51704 0.32588 0.35318 -0.00718 -0.05745 -0.03185 266 ILE A O     
2159 C  CB    . ILE A 269 ? 0.44461 0.25442 0.26849 -0.00364 -0.05608 -0.03188 266 ILE A CB    
2160 C  CG1   . ILE A 269 ? 0.49395 0.31810 0.32936 -0.00777 -0.06154 -0.02889 266 ILE A CG1   
2161 C  CG2   . ILE A 269 ? 0.50276 0.28237 0.29809 -0.01104 -0.06548 -0.03333 266 ILE A CG2   
2162 C  CD1   . ILE A 269 ? 0.47745 0.27997 0.28532 -0.00807 -0.06362 -0.03008 266 ILE A CD1   
2163 N  N     . PRO A 270 ? 0.54079 0.35558 0.37680 0.01101  -0.03827 -0.03443 267 PRO A N     
2164 C  CA    . PRO A 270 ? 0.55902 0.36113 0.38655 0.01505  -0.03440 -0.03583 267 PRO A CA    
2165 C  C     . PRO A 270 ? 0.49398 0.31429 0.34431 0.01149  -0.03694 -0.03355 267 PRO A C     
2166 O  O     . PRO A 270 ? 0.46191 0.26995 0.30467 0.00985  -0.03879 -0.03387 267 PRO A O     
2167 C  CB    . PRO A 270 ? 0.65364 0.45724 0.47997 0.02818  -0.02091 -0.03669 267 PRO A CB    
2168 C  CG    . PRO A 270 ? 0.69950 0.50421 0.52095 0.02975  -0.01863 -0.03682 267 PRO A CG    
2169 C  CD    . PRO A 270 ? 0.58406 0.40634 0.42261 0.02018  -0.02810 -0.03474 267 PRO A CD    
2170 N  N     . PHE A 271 ? 0.46142 0.30942 0.33819 0.01034  -0.03674 -0.03119 268 PHE A N     
2171 C  CA    . PHE A 271 ? 0.44463 0.31090 0.34289 0.00781  -0.03771 -0.02895 268 PHE A CA    
2172 C  C     . PHE A 271 ? 0.50921 0.37308 0.40907 -0.00345 -0.04806 -0.02685 268 PHE A C     
2173 O  O     . PHE A 271 ? 0.41754 0.28800 0.32754 -0.00604 -0.04890 -0.02509 268 PHE A O     
2174 C  CB    . PHE A 271 ? 0.43840 0.33120 0.36023 0.01046  -0.03383 -0.02748 268 PHE A CB    
2175 C  CG    . PHE A 271 ? 0.40980 0.32056 0.35133 0.01086  -0.03178 -0.02577 268 PHE A CG    
2176 C  CD1   . PHE A 271 ? 0.40190 0.31130 0.34295 0.01712  -0.02612 -0.02614 268 PHE A CD1   
2177 C  CD2   . PHE A 271 ? 0.37995 0.30894 0.34016 0.00577  -0.03494 -0.02351 268 PHE A CD2   
2178 C  CE1   . PHE A 271 ? 0.47497 0.39953 0.43196 0.01717  -0.02478 -0.02449 268 PHE A CE1   
2179 C  CE2   . PHE A 271 ? 0.38773 0.33127 0.36328 0.00646  -0.03235 -0.02217 268 PHE A CE2   
2180 C  CZ    . PHE A 271 ? 0.46131 0.40231 0.43454 0.01176  -0.02768 -0.02277 268 PHE A CZ    
2181 N  N     . TRP A 272 ? 0.42685 0.28080 0.31628 -0.01046 -0.05620 -0.02645 269 TRP A N     
2182 C  CA    . TRP A 272 ? 0.47042 0.32096 0.36077 -0.02206 -0.06714 -0.02350 269 TRP A CA    
2183 C  C     . TRP A 272 ? 0.48082 0.30620 0.35047 -0.02514 -0.07015 -0.02480 269 TRP A C     
2184 O  O     . TRP A 272 ? 0.52479 0.34965 0.39868 -0.03474 -0.07806 -0.02167 269 TRP A O     
2185 C  CB    . TRP A 272 ? 0.48207 0.32720 0.36523 -0.02908 -0.07638 -0.02218 269 TRP A CB    
2186 C  CG    . TRP A 272 ? 0.43403 0.30280 0.33796 -0.02811 -0.07583 -0.01979 269 TRP A CG    
2187 C  CD1   . TRP A 272 ? 0.52440 0.41945 0.45491 -0.02481 -0.07043 -0.01785 269 TRP A CD1   
2188 C  CD2   . TRP A 272 ? 0.45685 0.32287 0.35459 -0.03039 -0.08099 -0.01904 269 TRP A CD2   
2189 N  NE1   . TRP A 272 ? 0.43706 0.34546 0.37857 -0.02461 -0.07165 -0.01602 269 TRP A NE1   
2190 C  CE2   . TRP A 272 ? 0.40021 0.29195 0.32274 -0.02800 -0.07824 -0.01646 269 TRP A CE2   
2191 C  CE3   . TRP A 272 ? 0.48570 0.32819 0.35743 -0.03431 -0.08792 -0.02025 269 TRP A CE3   
2192 C  CZ2   . TRP A 272 ? 0.43605 0.33170 0.35966 -0.02908 -0.08208 -0.01473 269 TRP A CZ2   
2193 C  CZ3   . TRP A 272 ? 0.49654 0.34326 0.36884 -0.03572 -0.09205 -0.01849 269 TRP A CZ3   
2194 C  CH2   . TRP A 272 ? 0.46048 0.33420 0.35942 -0.03297 -0.08908 -0.01558 269 TRP A CH2   
2195 N  N     . LYS A 273 ? 0.49433 0.29788 0.34109 -0.01739 -0.06408 -0.02892 270 LYS A N     
2196 C  CA    . LYS A 273 ? 0.56503 0.34052 0.38850 -0.01877 -0.06587 -0.03067 270 LYS A CA    
2197 C  C     . LYS A 273 ? 0.66161 0.41673 0.46742 -0.03156 -0.07912 -0.02984 270 LYS A C     
2198 O  O     . LYS A 273 ? 0.60080 0.34754 0.40416 -0.04000 -0.08597 -0.02785 270 LYS A O     
2199 C  CB    . LYS A 273 ? 0.60117 0.38614 0.43883 -0.01821 -0.06318 -0.02870 270 LYS A CB    
2200 C  CG    . LYS A 273 ? 0.53277 0.32783 0.37856 -0.00521 -0.05104 -0.02996 270 LYS A CG    
2201 C  CD    . LYS A 273 ? 0.64072 0.40954 0.46040 0.00434  -0.04437 -0.03365 270 LYS A CD    
2202 C  CE    . LYS A 273 ? 0.72115 0.50262 0.55200 0.01733  -0.03270 -0.03355 270 LYS A CE    
2203 N  NZ    . LYS A 273 ? 0.70853 0.46444 0.51539 0.02754  -0.02530 -0.03607 270 LYS A NZ    
2204 N  N     . LEU A 274 ? 0.61255 0.35949 0.40575 -0.03362 -0.08332 -0.03090 271 LEU A N     
2205 C  CA    . LEU A 274 ? 0.73202 0.45755 0.50563 -0.04609 -0.09709 -0.03002 271 LEU A CA    
2206 C  C     . LEU A 274 ? 0.77800 0.46646 0.51830 -0.04610 -0.09753 -0.03344 271 LEU A C     
2207 O  O     . LEU A 274 ? 0.80431 0.47841 0.52885 -0.03409 -0.08624 -0.03757 271 LEU A O     
2208 C  CB    . LEU A 274 ? 0.69250 0.41326 0.45477 -0.04645 -0.10028 -0.03093 271 LEU A CB    
2209 C  CG    . LEU A 274 ? 0.60545 0.36040 0.39891 -0.04775 -0.10174 -0.02673 271 LEU A CG    
2210 C  CD1   . LEU A 274 ? 0.65605 0.40230 0.43441 -0.04808 -0.10525 -0.02753 271 LEU A CD1   
2211 C  CD2   . LEU A 274 ? 0.61040 0.38528 0.42910 -0.05954 -0.11225 -0.02036 271 LEU A CD2   
2212 N  N     . ASP A 275 ? 0.77966 0.46062 0.51554 -0.05756 -0.10784 -0.02895 272 ASP A N     
2213 C  CA    . ASP A 275 ? 0.90168 0.55368 0.61007 -0.05679 -0.10692 -0.02956 272 ASP A CA    
2214 C  C     . ASP A 275 ? 0.90615 0.53492 0.58487 -0.05463 -0.10715 -0.03083 272 ASP A C     
2215 O  O     . ASP A 275 ? 0.89561 0.52984 0.57410 -0.05106 -0.10515 -0.03217 272 ASP A O     
2216 C  CB    . ASP A 275 ? 0.93341 0.58532 0.64768 -0.06981 -0.11754 -0.02411 272 ASP A CB    
2217 C  CG    . ASP A 275 ? 0.89729 0.55539 0.61650 -0.08301 -0.13127 -0.01810 272 ASP A CG    
2218 O  OD1   . ASP A 275 ? 0.83498 0.49231 0.54791 -0.08240 -0.13334 -0.01837 272 ASP A OD1   
2219 O  OD2   . ASP A 275 ? 0.91141 0.57520 0.64113 -0.09401 -0.13996 -0.01243 272 ASP A OD2   
2220 N  N     . GLY A 276 ? 0.80916 0.41041 0.46124 -0.05699 -0.10965 -0.03018 273 GLY A N     
2221 C  CA    . GLY A 276 ? 0.85891 0.43333 0.47876 -0.05472 -0.10925 -0.03122 273 GLY A CA    
2222 C  C     . GLY A 276 ? 0.90125 0.47350 0.51632 -0.06635 -0.12243 -0.02697 273 GLY A C     
2223 O  O     . GLY A 276 ? 0.91794 0.46736 0.50553 -0.06464 -0.12229 -0.02770 273 GLY A O     
2224 N  N     . GLN A 277 ? 0.82782 0.42333 0.46925 -0.07781 -0.13349 -0.02192 274 GLN A N     
2225 C  CA    . GLN A 277 ? 0.78695 0.38253 0.42680 -0.08883 -0.14654 -0.01662 274 GLN A CA    
2226 C  C     . GLN A 277 ? 0.85804 0.45997 0.49777 -0.08348 -0.14341 -0.01841 274 GLN A C     
2227 O  O     . GLN A 277 ? 0.82873 0.44024 0.47509 -0.07239 -0.13188 -0.02320 274 GLN A O     
2228 C  CB    . GLN A 277 ? 0.86750 0.49065 0.54019 -0.10084 -0.15736 -0.00975 274 GLN A CB    
2229 C  CG    . GLN A 277 ? 0.92946 0.54863 0.60459 -0.10670 -0.16028 -0.00738 274 GLN A CG    
2230 C  CD    . GLN A 277 ? 0.90414 0.54980 0.61064 -0.11898 -0.17084 0.00076  274 GLN A CD    
2231 O  OE1   . GLN A 277 ? 0.96546 0.61124 0.67219 -0.12898 -0.18256 0.00702  274 GLN A OE1   
2232 N  NE2   . GLN A 277 ? 0.97149 0.64032 0.70542 -0.11797 -0.16632 0.00129  274 GLN A NE2   
2233 N  N     . GLN A 278 ? 0.76291 0.35915 0.39492 -0.09166 -0.15407 -0.01411 275 GLN A N     
2234 C  CA    . GLN A 278 ? 0.78036 0.38140 0.41117 -0.08781 -0.15246 -0.01503 275 GLN A CA    
2235 C  C     . GLN A 278 ? 0.72261 0.36128 0.39203 -0.09062 -0.15594 -0.01186 275 GLN A C     
2236 O  O     . GLN A 278 ? 0.76007 0.41683 0.45262 -0.10059 -0.16584 -0.00558 275 GLN A O     
2237 C  CB    . GLN A 278 ? 0.93963 0.51774 0.54539 -0.09540 -0.16276 -0.01137 275 GLN A CB    
2238 C  CG    . GLN A 278 ? 1.05087 0.58959 0.61429 -0.08988 -0.15687 -0.01526 275 GLN A CG    
2239 C  CD    . GLN A 278 ? 1.14763 0.68058 0.69884 -0.07551 -0.14171 -0.02134 275 GLN A CD    
2240 O  OE1   . GLN A 278 ? 1.22432 0.74360 0.76108 -0.06503 -0.12915 -0.02600 275 GLN A OE1   
2241 N  NE2   . GLN A 278 ? 1.08574 0.63006 0.64381 -0.07469 -0.14250 -0.02071 275 GLN A NE2   
2242 N  N     . TYR A 279 ? 0.72343 0.37403 0.39991 -0.08147 -0.14731 -0.01569 276 TYR A N     
2243 C  CA    . TYR A 279 ? 0.64670 0.33202 0.35840 -0.08223 -0.14887 -0.01337 276 TYR A CA    
2244 C  C     . TYR A 279 ? 0.72788 0.41545 0.43520 -0.07894 -0.14850 -0.01365 276 TYR A C     
2245 O  O     . TYR A 279 ? 0.72584 0.39365 0.40760 -0.07077 -0.14011 -0.01849 276 TYR A O     
2246 C  CB    . TYR A 279 ? 0.67313 0.37503 0.40305 -0.07394 -0.13795 -0.01796 276 TYR A CB    
2247 C  CG    . TYR A 279 ? 0.71147 0.41812 0.45354 -0.07883 -0.13994 -0.01611 276 TYR A CG    
2248 C  CD1   . TYR A 279 ? 0.62911 0.36155 0.40221 -0.08794 -0.14830 -0.00944 276 TYR A CD1   
2249 C  CD2   . TYR A 279 ? 0.71961 0.40456 0.44184 -0.07422 -0.13322 -0.02017 276 TYR A CD2   
2250 C  CE1   . TYR A 279 ? 0.68893 0.42524 0.47244 -0.09279 -0.14975 -0.00716 276 TYR A CE1   
2251 C  CE2   . TYR A 279 ? 0.70182 0.38961 0.43363 -0.07911 -0.13542 -0.01813 276 TYR A CE2   
2252 C  CZ    . TYR A 279 ? 0.81811 0.53139 0.58017 -0.08872 -0.14373 -0.01172 276 TYR A CZ    
2253 O  OH    . TYR A 279 ? 0.79450 0.51055 0.56581 -0.09374 -0.14530 -0.00924 276 TYR A OH    
2254 N  N     . ARG A 280 ? 0.66478 0.37606 0.39693 -0.08517 -0.15733 -0.00768 277 ARG A N     
2255 C  CA    . ARG A 280 ? 0.71119 0.43020 0.44541 -0.08210 -0.15738 -0.00717 277 ARG A CA    
2256 C  C     . ARG A 280 ? 0.63419 0.38599 0.40166 -0.07763 -0.15310 -0.00726 277 ARG A C     
2257 O  O     . ARG A 280 ? 0.56961 0.34648 0.36795 -0.08314 -0.15879 -0.00168 277 ARG A O     
2258 C  CB    . ARG A 280 ? 0.63323 0.35260 0.36902 -0.09200 -0.17108 0.00053  277 ARG A CB    
2259 C  CG    . ARG A 280 ? 0.68128 0.40703 0.41769 -0.08880 -0.17149 0.00146  277 ARG A CG    
2260 C  CD    . ARG A 280 ? 0.76401 0.48176 0.49346 -0.09801 -0.18454 0.00833  277 ARG A CD    
2261 N  NE    . ARG A 280 ? 0.74748 0.49039 0.50954 -0.10673 -0.19489 0.01700  277 ARG A NE    
2262 C  CZ    . ARG A 280 ? 0.83750 0.57836 0.60066 -0.11618 -0.20756 0.02466  277 ARG A CZ    
2263 N  NH1   . ARG A 280 ? 0.73731 0.45104 0.46987 -0.11904 -0.21266 0.02458  277 ARG A NH1   
2264 N  NH2   . ARG A 280 ? 0.86043 0.62667 0.65598 -0.12280 -0.21497 0.03296  277 ARG A NH2   
2265 N  N     . VAL A 281 ? 0.59340 0.34465 0.35438 -0.06741 -0.14253 -0.01314 278 VAL A N     
2266 C  CA    . VAL A 281 ? 0.53904 0.32087 0.33118 -0.06087 -0.13515 -0.01283 278 VAL A CA    
2267 C  C     . VAL A 281 ? 0.57586 0.36642 0.37180 -0.05893 -0.13656 -0.01007 278 VAL A C     
2268 O  O     . VAL A 281 ? 0.55558 0.32645 0.32475 -0.05452 -0.13252 -0.01341 278 VAL A O     
2269 C  CB    . VAL A 281 ? 0.50579 0.28771 0.29691 -0.04830 -0.11733 -0.01862 278 VAL A CB    
2270 C  CG1   . VAL A 281 ? 0.47569 0.29204 0.30346 -0.04171 -0.10835 -0.01658 278 VAL A CG1   
2271 C  CG2   . VAL A 281 ? 0.51568 0.28283 0.29656 -0.04983 -0.11638 -0.02156 278 VAL A CG2   
2272 N  N     . THR A 282 ? 0.50256 0.32161 0.33090 -0.06179 -0.14169 -0.00369 279 THR A N     
2273 C  CA    . THR A 282 ? 0.45664 0.28510 0.29119 -0.06066 -0.14461 0.00009  279 THR A CA    
2274 C  C     . THR A 282 ? 0.45642 0.31321 0.32130 -0.05116 -0.13215 0.00061  279 THR A C     
2275 O  O     . THR A 282 ? 0.42390 0.30189 0.31600 -0.05021 -0.12863 0.00216  279 THR A O     
2276 C  CB    . THR A 282 ? 0.48908 0.32563 0.33525 -0.07205 -0.16254 0.00832  279 THR A CB    
2277 O  OG1   . THR A 282 ? 0.53281 0.34514 0.35544 -0.07925 -0.16891 0.00911  279 THR A OG1   
2278 C  CG2   . THR A 282 ? 0.45114 0.29475 0.30095 -0.07040 -0.16613 0.01256  279 THR A CG2   
2279 N  N     . CYS A 283 ? 0.45153 0.30725 0.31022 -0.04447 -0.12548 -0.00058 280 CYS A N     
2280 C  CA    . CYS A 283 ? 0.36787 0.24788 0.25286 -0.03662 -0.11532 0.00032  280 CYS A CA    
2281 C  C     . CYS A 283 ? 0.44055 0.32642 0.32994 -0.03702 -0.12064 0.00521  280 CYS A C     
2282 O  O     . CYS A 283 ? 0.43188 0.29859 0.29623 -0.03952 -0.12633 0.00546  280 CYS A O     
2283 C  CB    . CYS A 283 ? 0.47061 0.34618 0.34764 -0.02694 -0.09937 -0.00585 280 CYS A CB    
2284 S  SG    . CYS A 283 ? 0.53696 0.39031 0.38246 -0.02206 -0.09356 -0.00863 280 CYS A SG    
2285 N  N     . PHE A 284 ? 0.40586 0.31703 0.32619 -0.03469 -0.11919 0.00939  281 PHE A N     
2286 C  CA    . PHE A 284 ? 0.40151 0.32134 0.33097 -0.03368 -0.12299 0.01461  281 PHE A CA    
2287 C  C     . PHE A 284 ? 0.33599 0.26669 0.27667 -0.02434 -0.10883 0.01200  281 PHE A C     
2288 O  O     . PHE A 284 ? 0.36570 0.31497 0.33060 -0.02090 -0.10265 0.01210  281 PHE A O     
2289 C  CB    . PHE A 284 ? 0.37481 0.31453 0.33172 -0.03831 -0.13301 0.02247  281 PHE A CB    
2290 C  CG    . PHE A 284 ? 0.39491 0.32750 0.34580 -0.04875 -0.14734 0.02588  281 PHE A CG    
2291 C  CD1   . PHE A 284 ? 0.41319 0.34923 0.37125 -0.05216 -0.14696 0.02454  281 PHE A CD1   
2292 C  CD2   . PHE A 284 ? 0.35347 0.27571 0.29161 -0.05588 -0.16203 0.03100  281 PHE A CD2   
2293 C  CE1   . PHE A 284 ? 0.41673 0.34563 0.36933 -0.06285 -0.16073 0.02812  281 PHE A CE1   
2294 C  CE2   . PHE A 284 ? 0.43731 0.35254 0.36997 -0.06663 -0.17605 0.03462  281 PHE A CE2   
2295 C  CZ    . PHE A 284 ? 0.42796 0.34652 0.36831 -0.07006 -0.17452 0.03313  281 PHE A CZ    
2296 N  N     . THR A 285 ? 0.35094 0.26919 0.27308 -0.02062 -0.10363 0.00983  282 THR A N     
2297 C  CA    . THR A 285 ? 0.32974 0.25505 0.25865 -0.01280 -0.08992 0.00684  282 THR A CA    
2298 C  C     . THR A 285 ? 0.34241 0.27120 0.27489 -0.01066 -0.09044 0.01083  282 THR A C     
2299 O  O     . THR A 285 ? 0.34423 0.26009 0.25947 -0.01362 -0.09782 0.01355  282 THR A O     
2300 C  CB    . THR A 285 ? 0.34830 0.25695 0.25384 -0.00945 -0.08062 0.00097  282 THR A CB    
2301 O  OG1   . THR A 285 ? 0.38745 0.30523 0.30237 -0.00265 -0.06782 -0.00106 282 THR A OG1   
2302 C  CG2   . THR A 285 ? 0.38867 0.27339 0.26231 -0.01146 -0.08456 0.00101  282 THR A CG2   
2303 N  N     . SER A 286 ? 0.29211 0.23699 0.24580 -0.00578 -0.08313 0.01136  283 SER A N     
2304 C  CA    . SER A 286 ? 0.27766 0.22614 0.23692 -0.00390 -0.08444 0.01579  283 SER A CA    
2305 C  C     . SER A 286 ? 0.31457 0.24772 0.25127 -0.00210 -0.07960 0.01462  283 SER A C     
2306 O  O     . SER A 286 ? 0.38108 0.30890 0.31129 -0.00284 -0.08463 0.01890  283 SER A O     
2307 C  CB    . SER A 286 ? 0.29541 0.26184 0.28046 0.00078  -0.07767 0.01629  283 SER A CB    
2308 O  OG    . SER A 286 ? 0.26833 0.23663 0.25429 0.00453  -0.06596 0.01114  283 SER A OG    
2309 N  N     . TRP A 287 ? 0.34109 0.26721 0.26591 0.00046  -0.06975 0.00958  284 TRP A N     
2310 C  CA    . TRP A 287 ? 0.33879 0.24954 0.24056 0.00231  -0.06382 0.00868  284 TRP A CA    
2311 C  C     . TRP A 287 ? 0.33845 0.23129 0.21527 0.00107  -0.06355 0.00500  284 TRP A C     
2312 O  O     . TRP A 287 ? 0.36760 0.26332 0.24878 0.00164  -0.06072 0.00137  284 TRP A O     
2313 C  CB    . TRP A 287 ? 0.31987 0.23825 0.23001 0.00740  -0.05051 0.00682  284 TRP A CB    
2314 C  CG    . TRP A 287 ? 0.31107 0.24065 0.23816 0.00892  -0.04884 0.01006  284 TRP A CG    
2315 C  CD1   . TRP A 287 ? 0.32230 0.26773 0.27254 0.01084  -0.04477 0.00928  284 TRP A CD1   
2316 C  CD2   . TRP A 287 ? 0.33549 0.25900 0.25551 0.00875  -0.05070 0.01436  284 TRP A CD2   
2317 N  NE1   . TRP A 287 ? 0.27109 0.21970 0.22871 0.01185  -0.04411 0.01262  284 TRP A NE1   
2318 C  CE2   . TRP A 287 ? 0.33904 0.27503 0.27929 0.01069  -0.04761 0.01598  284 TRP A CE2   
2319 C  CE3   . TRP A 287 ? 0.32998 0.23707 0.22683 0.00705  -0.05486 0.01710  284 TRP A CE3   
2320 C  CZ2   . TRP A 287 ? 0.35197 0.28489 0.29112 0.01111  -0.04854 0.02036  284 TRP A CZ2   
2321 C  CZ3   . TRP A 287 ? 0.31751 0.22259 0.21361 0.00743  -0.05575 0.02171  284 TRP A CZ3   
2322 C  CH2   . TRP A 287 ? 0.36731 0.28549 0.28512 0.00952  -0.05256 0.02336  284 TRP A CH2   
2323 N  N     . SER A 288 ? 0.42344 0.29619 0.27249 -0.00020 -0.06580 0.00586  285 SER A N     
2324 C  CA    . SER A 288 ? 0.39860 0.25064 0.21979 0.00015  -0.06273 0.00188  285 SER A CA    
2325 C  C     . SER A 288 ? 0.42307 0.27906 0.24720 0.00705  -0.04680 -0.00167 285 SER A C     
2326 O  O     . SER A 288 ? 0.38548 0.25508 0.22542 0.01064  -0.03863 -0.00025 285 SER A O     
2327 C  CB    . SER A 288 ? 0.44904 0.27733 0.23764 -0.00157 -0.06615 0.00354  285 SER A CB    
2328 O  OG    . SER A 288 ? 0.46505 0.29382 0.25096 0.00267  -0.05683 0.00564  285 SER A OG    
2329 N  N     . PRO A 289 ? 0.44127 0.28574 0.25122 0.00891  -0.04249 -0.00583 286 PRO A N     
2330 C  CA    . PRO A 289 ? 0.40410 0.25526 0.22087 0.01589  -0.02787 -0.00820 286 PRO A CA    
2331 C  C     . PRO A 289 ? 0.43096 0.27492 0.23424 0.02099  -0.01621 -0.00665 286 PRO A C     
2332 O  O     . PRO A 289 ? 0.46463 0.28777 0.23988 0.02047  -0.01708 -0.00599 286 PRO A O     
2333 C  CB    . PRO A 289 ? 0.45897 0.29554 0.25997 0.01661  -0.02757 -0.01246 286 PRO A CB    
2334 C  CG    . PRO A 289 ? 0.46982 0.28340 0.24353 0.01064  -0.03926 -0.01251 286 PRO A CG    
2335 C  CD    . PRO A 289 ? 0.41311 0.23906 0.20263 0.00448  -0.05135 -0.00818 286 PRO A CD    
2336 N  N     . CYS A 290 ? 0.43307 0.29430 0.25634 0.02556  -0.00539 -0.00566 287 CYS A N     
2337 C  CA    . CYS A 290 ? 0.46340 0.32151 0.27855 0.03099  0.00796  -0.00361 287 CYS A CA    
2338 C  C     . CYS A 290 ? 0.49061 0.33023 0.28156 0.03662  0.01676  -0.00628 287 CYS A C     
2339 O  O     . CYS A 290 ? 0.46577 0.29554 0.24763 0.03614  0.01241  -0.01008 287 CYS A O     
2340 C  CB    . CYS A 290 ? 0.42117 0.30367 0.26613 0.03347  0.01600  -0.00154 287 CYS A CB    
2341 S  SG    . CYS A 290 ? 0.41500 0.30951 0.27617 0.03809  0.02252  -0.00446 287 CYS A SG    
2342 N  N     . PHE A 291 ? 0.56973 0.40409 0.35003 0.04231  0.02995  -0.00392 288 PHE A N     
2343 C  CA    . PHE A 291 ? 0.60932 0.42360 0.36380 0.04907  0.04005  -0.00601 288 PHE A CA    
2344 C  C     . PHE A 291 ? 0.57911 0.40133 0.34668 0.05337  0.04405  -0.00879 288 PHE A C     
2345 O  O     . PHE A 291 ? 0.54577 0.34844 0.29221 0.05543  0.04353  -0.01269 288 PHE A O     
2346 C  CB    . PHE A 291 ? 0.57993 0.39201 0.32646 0.05550  0.05582  -0.00182 288 PHE A CB    
2347 C  CG    . PHE A 291 ? 0.68458 0.47599 0.40483 0.06419  0.06856  -0.00347 288 PHE A CG    
2348 C  CD1   . PHE A 291 ? 0.69324 0.45191 0.37425 0.06366  0.06455  -0.00727 288 PHE A CD1   
2349 C  CD2   . PHE A 291 ? 0.75976 0.56373 0.49437 0.07290  0.08398  -0.00108 288 PHE A CD2   
2350 C  CE1   . PHE A 291 ? 0.82263 0.55902 0.47660 0.07236  0.07688  -0.00923 288 PHE A CE1   
2351 C  CE2   . PHE A 291 ? 0.79978 0.58408 0.51030 0.08233  0.09683  -0.00229 288 PHE A CE2   
2352 C  CZ    . PHE A 291 ? 0.82302 0.57239 0.49209 0.08234  0.09370  -0.00672 288 PHE A CZ    
2353 N  N     . SER A 292 ? 0.52366 0.37299 0.32468 0.05446  0.04746  -0.00674 289 SER A N     
2354 C  CA    . SER A 292 ? 0.59643 0.45338 0.40953 0.05908  0.05177  -0.00858 289 SER A CA    
2355 C  C     . SER A 292 ? 0.52563 0.37782 0.33807 0.05394  0.03889  -0.01316 289 SER A C     
2356 O  O     . SER A 292 ? 0.51315 0.35593 0.31735 0.05767  0.04113  -0.01602 289 SER A O     
2357 C  CB    . SER A 292 ? 0.56895 0.45545 0.41697 0.06046  0.05710  -0.00479 289 SER A CB    
2358 O  OG    . SER A 292 ? 0.71133 0.61414 0.58160 0.05332  0.04580  -0.00550 289 SER A OG    
2359 N  N     . CYS A 293 ? 0.48441 0.34242 0.30523 0.04566  0.02576  -0.01340 290 CYS A N     
2360 C  CA    . CYS A 293 ? 0.45603 0.30957 0.27606 0.04010  0.01344  -0.01670 290 CYS A CA    
2361 C  C     . CYS A 293 ? 0.51881 0.34203 0.30377 0.03900  0.00936  -0.01967 290 CYS A C     
2362 O  O     . CYS A 293 ? 0.53312 0.34660 0.31065 0.03881  0.00655  -0.02284 290 CYS A O     
2363 C  CB    . CYS A 293 ? 0.42392 0.29063 0.26085 0.03235  0.00144  -0.01512 290 CYS A CB    
2364 S  SG    . CYS A 293 ? 0.37184 0.27025 0.24804 0.03213  0.00283  -0.01343 290 CYS A SG    
2365 N  N     . ALA A 294 ? 0.49650 0.30297 0.25812 0.03766  0.00829  -0.01859 291 ALA A N     
2366 C  CA    . ALA A 294 ? 0.53522 0.31012 0.26021 0.03522  0.00255  -0.02139 291 ALA A CA    
2367 C  C     . ALA A 294 ? 0.61968 0.37495 0.32239 0.04362  0.01458  -0.02438 291 ALA A C     
2368 O  O     . ALA A 294 ? 0.61282 0.34331 0.28988 0.04175  0.00942  -0.02803 291 ALA A O     
2369 C  CB    . ALA A 294 ? 0.61524 0.37626 0.31909 0.03233  -0.00068 -0.01910 291 ALA A CB    
2370 N  N     . GLN A 295 ? 0.56836 0.33429 0.28106 0.05287  0.03052  -0.02242 292 GLN A N     
2371 C  CA    . GLN A 295 ? 0.66166 0.41267 0.35820 0.06271  0.04380  -0.02425 292 GLN A CA    
2372 C  C     . GLN A 295 ? 0.67751 0.43245 0.38534 0.06292  0.04028  -0.02715 292 GLN A C     
2373 O  O     . GLN A 295 ? 0.65981 0.38986 0.34257 0.06579  0.04158  -0.03077 292 GLN A O     
2374 C  CB    . GLN A 295 ? 0.67353 0.44198 0.38637 0.07188  0.06079  -0.01973 292 GLN A CB    
2375 C  CG    . GLN A 295 ? 0.94032 0.68681 0.62292 0.07957  0.07443  -0.01856 292 GLN A CG    
2376 C  CD    . GLN A 295 ? 1.03063 0.79295 0.72987 0.09080  0.09320  -0.01406 292 GLN A CD    
2377 O  OE1   . GLN A 295 ? 1.00511 0.79840 0.74125 0.09090  0.09450  -0.01073 292 GLN A OE1   
2378 N  NE2   . GLN A 295 ? 0.95602 0.69707 0.62815 0.10017  0.10772  -0.01339 292 GLN A NE2   
2379 N  N     . GLU A 296 ? 0.57042 0.35481 0.31429 0.05967  0.03565  -0.02560 293 GLU A N     
2380 C  CA    . GLU A 296 ? 0.59671 0.38604 0.35231 0.05924  0.03185  -0.02783 293 GLU A CA    
2381 C  C     . GLU A 296 ? 0.60852 0.37992 0.34761 0.05014  0.01684  -0.03126 293 GLU A C     
2382 O  O     . GLU A 296 ? 0.61082 0.36919 0.34033 0.05085  0.01537  -0.03413 293 GLU A O     
2383 C  CB    . GLU A 296 ? 0.52204 0.34578 0.31777 0.05741  0.03027  -0.02519 293 GLU A CB    
2384 C  CG    . GLU A 296 ? 0.64361 0.48447 0.45716 0.06648  0.04439  -0.02182 293 GLU A CG    
2385 C  CD    . GLU A 296 ? 0.86431 0.69670 0.67190 0.07496  0.05257  -0.02295 293 GLU A CD    
2386 O  OE1   . GLU A 296 ? 0.91191 0.73738 0.71675 0.07222  0.04541  -0.02604 293 GLU A OE1   
2387 O  OE2   . GLU A 296 ? 0.87663 0.70885 0.68212 0.08463  0.06651  -0.02026 293 GLU A OE2   
2388 N  N     . MET A 297 ? 0.53623 0.30695 0.27249 0.04136  0.00532  -0.03036 294 MET A N     
2389 C  CA    . MET A 297 ? 0.57326 0.32669 0.29310 0.03178  -0.00987 -0.03235 294 MET A CA    
2390 C  C     . MET A 297 ? 0.66396 0.37903 0.34063 0.03365  -0.00829 -0.03586 294 MET A C     
2391 O  O     . MET A 297 ? 0.65168 0.34862 0.31309 0.02898  -0.01632 -0.03865 294 MET A O     
2392 C  CB    . MET A 297 ? 0.55354 0.31589 0.28072 0.02331  -0.02142 -0.02933 294 MET A CB    
2393 C  CG    . MET A 297 ? 0.54162 0.33633 0.30787 0.01906  -0.02730 -0.02665 294 MET A CG    
2394 S  SD    . MET A 297 ? 0.56774 0.37366 0.34428 0.01140  -0.03885 -0.02223 294 MET A SD    
2395 C  CE    . MET A 297 ? 0.53877 0.35495 0.33327 0.00203  -0.05383 -0.02135 294 MET A CE    
2396 N  N     . ALA A 298 ? 0.62928 0.33021 0.28460 0.04057  0.00264  -0.03566 295 ALA A N     
2397 C  CA    . ALA A 298 ? 0.68047 0.34181 0.29095 0.04347  0.00582  -0.03925 295 ALA A CA    
2398 C  C     . ALA A 298 ? 0.79607 0.45041 0.40500 0.05171  0.01584  -0.04087 295 ALA A C     
2399 O  O     . ALA A 298 ? 0.79361 0.42488 0.38247 0.04941  0.01202  -0.04144 295 ALA A O     
2400 C  CB    . ALA A 298 ? 0.70051 0.35194 0.29277 0.04922  0.01645  -0.03712 295 ALA A CB    
2401 N  N     . LYS A 299 ? 0.70125 0.37840 0.33576 0.06072  0.02796  -0.03990 296 LYS A N     
2402 C  CA    . LYS A 299 ? 0.75794 0.43309 0.39659 0.06831  0.03606  -0.04044 296 LYS A CA    
2403 C  C     . LYS A 299 ? 0.84309 0.51316 0.48333 0.06018  0.02265  -0.04330 296 LYS A C     
2404 O  O     . LYS A 299 ? 0.73407 0.38684 0.36099 0.06144  0.02315  -0.04358 296 LYS A O     
2405 C  CB    . LYS A 299 ? 0.72243 0.42846 0.39453 0.07743  0.04846  -0.03751 296 LYS A CB    
2406 C  CG    . LYS A 299 ? 0.83757 0.54286 0.51419 0.08751  0.05938  -0.03640 296 LYS A CG    
2407 C  CD    . LYS A 299 ? 0.92399 0.65724 0.62909 0.09757  0.07369  -0.03171 296 LYS A CD    
2408 C  CE    . LYS A 299 ? 1.13221 0.86429 0.82965 0.10259  0.08485  -0.02768 296 LYS A CE    
2409 N  NZ    . LYS A 299 ? 1.17016 0.93157 0.89830 0.11113  0.09796  -0.02171 296 LYS A NZ    
2410 N  N     . PHE A 300 ? 0.66802 0.36009 0.33311 0.05060  0.01026  -0.04244 297 PHE A N     
2411 C  CA    . PHE A 300 ? 0.70487 0.39669 0.37654 0.04231  -0.00206 -0.04381 297 PHE A CA    
2412 C  C     . PHE A 300 ? 0.81519 0.47249 0.45140 0.03410  -0.01337 -0.04647 297 PHE A C     
2413 O  O     . PHE A 300 ? 0.74153 0.38605 0.37033 0.03274  -0.01563 -0.04687 297 PHE A O     
2414 C  CB    . PHE A 300 ? 0.57613 0.30058 0.28352 0.03357  -0.01237 -0.04064 297 PHE A CB    
2415 C  CG    . PHE A 300 ? 0.65793 0.38619 0.37624 0.02565  -0.02325 -0.04102 297 PHE A CG    
2416 C  CD1   . PHE A 300 ? 0.66750 0.41307 0.40879 0.02982  -0.01821 -0.04052 297 PHE A CD1   
2417 C  CD2   . PHE A 300 ? 0.65817 0.37235 0.36338 0.01376  -0.03866 -0.04128 297 PHE A CD2   
2418 C  CE1   . PHE A 300 ? 0.69828 0.44679 0.44878 0.02262  -0.02736 -0.04048 297 PHE A CE1   
2419 C  CE2   . PHE A 300 ? 0.65562 0.37413 0.37199 0.00619  -0.04800 -0.04079 297 PHE A CE2   
2420 C  CZ    . PHE A 300 ? 0.69943 0.43467 0.43786 0.01083  -0.04182 -0.04052 297 PHE A CZ    
2421 N  N     . ILE A 301 ? 0.74556 0.39462 0.36800 0.02736  -0.02117 -0.04519 298 ILE A N     
2422 C  CA    . ILE A 301 ? 0.75560 0.38002 0.35396 0.01808  -0.03279 -0.04396 298 ILE A CA    
2423 C  C     . ILE A 301 ? 0.94958 0.54800 0.52336 0.02489  -0.02367 -0.04427 298 ILE A C     
2424 O  O     . ILE A 301 ? 0.87452 0.45512 0.43488 0.01883  -0.03161 -0.04407 298 ILE A O     
2425 C  CB    . ILE A 301 ? 0.82130 0.44001 0.40729 0.01294  -0.03899 -0.04188 298 ILE A CB    
2426 C  CG1   . ILE A 301 ? 0.95872 0.59854 0.56617 0.00232  -0.05403 -0.04020 298 ILE A CG1   
2427 C  CG2   . ILE A 301 ? 1.01907 0.60615 0.57345 0.00769  -0.04522 -0.04049 298 ILE A CG2   
2428 C  CD1   . ILE A 301 ? 0.94000 0.57504 0.53654 -0.00256 -0.06073 -0.03732 298 ILE A CD1   
2429 N  N     . SER A 302 ? 0.92644 0.52274 0.49457 0.03759  -0.00675 -0.04407 299 SER A N     
2430 C  CA    . SER A 302 ? 1.07271 0.64370 0.61638 0.04500  0.00279  -0.04360 299 SER A CA    
2431 C  C     . SER A 302 ? 1.00141 0.57266 0.55219 0.04903  0.00618  -0.04443 299 SER A C     
2432 O  O     . SER A 302 ? 1.03878 0.58515 0.56660 0.05171  0.00905  -0.04412 299 SER A O     
2433 C  CB    . SER A 302 ? 0.99358 0.56603 0.53351 0.05747  0.02028  -0.04189 299 SER A CB    
2434 O  OG    . SER A 302 ? 1.07554 0.64731 0.60834 0.05338  0.01690  -0.04099 299 SER A OG    
2435 N  N     . ASN A 303 ? 0.97670 0.57376 0.55721 0.04932  0.00551  -0.04536 300 ASN A N     
2436 C  CA    . ASN A 303 ? 0.99661 0.59472 0.58497 0.05281  0.00808  -0.04585 300 ASN A CA    
2437 C  C     . ASN A 303 ? 0.96651 0.56680 0.56269 0.04031  -0.00791 -0.04701 300 ASN A C     
2438 O  O     . ASN A 303 ? 0.97121 0.57424 0.57616 0.04199  -0.00705 -0.04739 300 ASN A O     
2439 C  CB    . ASN A 303 ? 1.04154 0.66636 0.65816 0.06420  0.02123  -0.04507 300 ASN A CB    
2440 C  CG    . ASN A 303 ? 1.10323 0.73588 0.72166 0.07390  0.03498  -0.04283 300 ASN A CG    
2441 O  OD1   . ASN A 303 ? 1.18506 0.79743 0.77900 0.07653  0.03971  -0.04167 300 ASN A OD1   
2442 N  ND2   . ASN A 303 ? 1.08450 0.74627 0.73203 0.07918  0.04164  -0.04170 300 ASN A ND2   
2443 N  N     . ASN A 304 ? 0.95445 0.55428 0.54862 0.02762  -0.02262 -0.04676 301 ASN A N     
2444 C  CA    . ASN A 304 ? 0.95853 0.56350 0.56340 0.01468  -0.03834 -0.04638 301 ASN A CA    
2445 C  C     . ASN A 304 ? 0.90386 0.49136 0.48956 0.00235  -0.05263 -0.04422 301 ASN A C     
2446 O  O     . ASN A 304 ? 0.91152 0.51161 0.50830 -0.00657 -0.06347 -0.04257 301 ASN A O     
2447 C  CB    . ASN A 304 ? 0.90415 0.54048 0.54204 0.01184  -0.04208 -0.04686 301 ASN A CB    
2448 C  CG    . ASN A 304 ? 0.96211 0.61499 0.61922 0.02357  -0.02888 -0.04843 301 ASN A CG    
2449 O  OD1   . ASN A 304 ? 0.83280 0.49065 0.50156 0.02298  -0.03010 -0.04875 301 ASN A OD1   
2450 N  ND2   . ASN A 304 ? 0.82379 0.48575 0.48509 0.03414  -0.01625 -0.04865 301 ASN A ND2   
2451 N  N     . GLU A 305 ? 0.95056 0.50865 0.50766 0.00167  -0.05321 -0.04366 302 GLU A N     
2452 C  CA    . GLU A 305 ? 0.97599 0.51412 0.51135 -0.00872 -0.06543 -0.04125 302 GLU A CA    
2453 C  C     . GLU A 305 ? 0.88256 0.42580 0.42835 -0.02407 -0.08340 -0.03823 302 GLU A C     
2454 O  O     . GLU A 305 ? 1.01391 0.54858 0.55007 -0.03409 -0.09553 -0.03512 302 GLU A O     
2455 C  CB    . GLU A 305 ? 1.23820 0.74072 0.73662 -0.00338 -0.05890 -0.04158 302 GLU A CB    
2456 C  CG    . GLU A 305 ? 1.33454 0.83635 0.82705 0.01179  -0.04058 -0.04320 302 GLU A CG    
2457 C  CD    . GLU A 305 ? 1.63675 1.10576 1.09255 0.01506  -0.03615 -0.04252 302 GLU A CD    
2458 O  OE1   . GLU A 305 ? 1.74075 1.19487 1.18021 0.00494  -0.04820 -0.04089 302 GLU A OE1   
2459 O  OE2   . GLU A 305 ? 1.67544 1.13517 1.12030 0.02815  -0.02014 -0.04313 302 GLU A OE2   
2460 N  N     . HIS A 306 ? 0.79472 0.35326 0.36173 -0.02628 -0.08539 -0.03836 303 HIS A N     
2461 C  CA    . HIS A 306 ? 0.95993 0.52996 0.54346 -0.04076 -0.10158 -0.03440 303 HIS A CA    
2462 C  C     . HIS A 306 ? 0.89492 0.49627 0.50872 -0.04560 -0.10783 -0.03241 303 HIS A C     
2463 O  O     . HIS A 306 ? 0.83041 0.44584 0.46248 -0.05713 -0.12067 -0.02793 303 HIS A O     
2464 C  CB    . HIS A 306 ? 0.85436 0.42840 0.44893 -0.04201 -0.10154 -0.03461 303 HIS A CB    
2465 C  CG    . HIS A 306 ? 0.92292 0.52227 0.54480 -0.03423 -0.09237 -0.03733 303 HIS A CG    
2466 N  ND1   . HIS A 306 ? 1.07466 0.67760 0.69645 -0.02014 -0.07723 -0.04115 303 HIS A ND1   
2467 C  CD2   . HIS A 306 ? 0.95997 0.58148 0.60977 -0.03863 -0.09609 -0.03624 303 HIS A CD2   
2468 C  CE1   . HIS A 306 ? 0.97811 0.60385 0.62618 -0.01639 -0.07278 -0.04248 303 HIS A CE1   
2469 N  NE2   . HIS A 306 ? 0.98839 0.62492 0.65300 -0.02746 -0.08400 -0.03979 303 HIS A NE2   
2470 N  N     . VAL A 307 ? 0.79979 0.41233 0.41927 -0.03703 -0.09899 -0.03491 304 VAL A N     
2471 C  CA    . VAL A 307 ? 0.79418 0.43490 0.44012 -0.04044 -0.10411 -0.03313 304 VAL A CA    
2472 C  C     . VAL A 307 ? 0.81219 0.44441 0.44315 -0.04181 -0.10735 -0.03147 304 VAL A C     
2473 O  O     . VAL A 307 ? 0.82147 0.43962 0.43255 -0.03247 -0.09639 -0.03434 304 VAL A O     
2474 C  CB    . VAL A 307 ? 0.84676 0.50841 0.51256 -0.03013 -0.09224 -0.03697 304 VAL A CB    
2475 C  CG1   . VAL A 307 ? 0.72723 0.41553 0.41710 -0.03327 -0.09764 -0.03502 304 VAL A CG1   
2476 C  CG2   . VAL A 307 ? 0.76300 0.43288 0.44422 -0.02940 -0.09000 -0.03817 304 VAL A CG2   
2477 N  N     . SER A 308 ? 0.75736 0.39875 0.39888 -0.05318 -0.12194 -0.02611 305 SER A N     
2478 C  CA    . SER A 308 ? 0.75166 0.39051 0.38529 -0.05531 -0.12663 -0.02366 305 SER A CA    
2479 C  C     . SER A 308 ? 0.73845 0.40908 0.40174 -0.05339 -0.12631 -0.02281 305 SER A C     
2480 O  O     . SER A 308 ? 0.76618 0.46180 0.45956 -0.05926 -0.13372 -0.01935 305 SER A O     
2481 C  CB    . SER A 308 ? 0.76093 0.39128 0.38953 -0.06847 -0.14295 -0.01737 305 SER A CB    
2482 O  OG    . SER A 308 ? 0.88794 0.48626 0.48620 -0.07060 -0.14388 -0.01806 305 SER A OG    
2483 N  N     . LEU A 309 ? 0.67226 0.34189 0.32719 -0.04484 -0.11706 -0.02553 306 LEU A N     
2484 C  CA    . LEU A 309 ? 0.65111 0.34778 0.33010 -0.04175 -0.11549 -0.02508 306 LEU A CA    
2485 C  C     . LEU A 309 ? 0.64871 0.34967 0.32897 -0.04757 -0.12562 -0.01972 306 LEU A C     
2486 O  O     . LEU A 309 ? 0.62418 0.30288 0.27781 -0.04749 -0.12545 -0.01944 306 LEU A O     
2487 C  CB    . LEU A 309 ? 0.59186 0.28826 0.26527 -0.02804 -0.09724 -0.02976 306 LEU A CB    
2488 C  CG    . LEU A 309 ? 0.67306 0.40261 0.37959 -0.02195 -0.08930 -0.02672 306 LEU A CG    
2489 C  CD1   . LEU A 309 ? 0.68862 0.45093 0.43625 -0.02443 -0.09191 -0.02369 306 LEU A CD1   
2490 C  CD2   . LEU A 309 ? 0.68592 0.41381 0.38689 -0.00898 -0.07050 -0.02987 306 LEU A CD2   
2491 N  N     . CYS A 310 ? 0.60219 0.33156 0.31385 -0.05214 -0.13403 -0.01502 307 CYS A N     
2492 C  CA    . CYS A 310 ? 0.59466 0.33220 0.31283 -0.05668 -0.14340 -0.00896 307 CYS A CA    
2493 C  C     . CYS A 310 ? 0.51940 0.28644 0.26705 -0.04970 -0.13612 -0.00719 307 CYS A C     
2494 O  O     . CYS A 310 ? 0.51296 0.30678 0.29448 -0.04822 -0.13294 -0.00552 307 CYS A O     
2495 C  CB    . CYS A 310 ? 0.57443 0.32293 0.31185 -0.06809 -0.15829 -0.00141 307 CYS A CB    
2496 S  SG    . CYS A 310 ? 0.73714 0.45419 0.44652 -0.07645 -0.16522 -0.00072 307 CYS A SG    
2497 N  N     . ILE A 311 ? 0.54510 0.30803 0.28224 -0.04496 -0.13159 -0.00675 308 ILE A N     
2498 C  CA    . ILE A 311 ? 0.50521 0.29453 0.27024 -0.03773 -0.12248 -0.00446 308 ILE A CA    
2499 C  C     . ILE A 311 ? 0.51365 0.31006 0.28529 -0.04271 -0.13439 0.00229  308 ILE A C     
2500 O  O     . ILE A 311 ? 0.57441 0.34907 0.31724 -0.04574 -0.14074 0.00313  308 ILE A O     
2501 C  CB    . ILE A 311 ? 0.52656 0.30808 0.27775 -0.02717 -0.10527 -0.00880 308 ILE A CB    
2502 C  CG1   . ILE A 311 ? 0.61895 0.39735 0.36875 -0.02133 -0.09339 -0.01436 308 ILE A CG1   
2503 C  CG2   . ILE A 311 ? 0.46889 0.27566 0.24715 -0.02156 -0.09808 -0.00571 308 ILE A CG2   
2504 C  CD1   . ILE A 311 ? 0.65817 0.41212 0.37609 -0.01406 -0.08124 -0.01889 308 ILE A CD1   
2505 N  N     . PHE A 312 ? 0.47194 0.29758 0.28034 -0.04331 -0.13748 0.00737  309 PHE A N     
2506 C  CA    . PHE A 312 ? 0.46463 0.30211 0.28602 -0.04511 -0.14562 0.01434  309 PHE A CA    
2507 C  C     . PHE A 312 ? 0.44167 0.29851 0.28460 -0.03566 -0.13210 0.01417  309 PHE A C     
2508 O  O     . PHE A 312 ? 0.43052 0.30561 0.29730 -0.03129 -0.12321 0.01229  309 PHE A O     
2509 C  CB    . PHE A 312 ? 0.43224 0.28831 0.28024 -0.05271 -0.15974 0.02147  309 PHE A CB    
2510 C  CG    . PHE A 312 ? 0.52229 0.36102 0.35205 -0.06391 -0.17537 0.02349  309 PHE A CG    
2511 C  CD1   . PHE A 312 ? 0.54246 0.36966 0.35962 -0.06887 -0.18381 0.02811  309 PHE A CD1   
2512 C  CD2   . PHE A 312 ? 0.46144 0.29755 0.29290 -0.06799 -0.17544 0.02105  309 PHE A CD2   
2513 C  CE1   . PHE A 312 ? 0.57800 0.39087 0.38405 -0.07799 -0.19266 0.03029  309 PHE A CE1   
2514 C  CE2   . PHE A 312 ? 0.51746 0.33896 0.33750 -0.07692 -0.18389 0.02348  309 PHE A CE2   
2515 C  CZ    . PHE A 312 ? 0.59814 0.40799 0.40551 -0.08204 -0.19276 0.02815  309 PHE A CZ    
2516 N  N     . ALA A 313 ? 0.46569 0.31748 0.29925 -0.03307 -0.13109 0.01635  310 ALA A N     
2517 C  CA    . ALA A 313 ? 0.45994 0.32655 0.31028 -0.02501 -0.11893 0.01642  310 ALA A CA    
2518 C  C     . ALA A 313 ? 0.43591 0.31539 0.30336 -0.02589 -0.12693 0.02390  310 ALA A C     
2519 O  O     . ALA A 313 ? 0.43201 0.30086 0.28575 -0.03129 -0.13964 0.02856  310 ALA A O     
2520 C  CB    . ALA A 313 ? 0.41571 0.26472 0.23994 -0.01979 -0.10738 0.01243  310 ALA A CB    
2521 N  N     . ALA A 314 ? 0.37792 0.27913 0.27432 -0.02045 -0.11970 0.02524  311 ALA A N     
2522 C  CA    . ALA A 314 ? 0.42429 0.33650 0.33653 -0.01944 -0.12514 0.03224  311 ALA A CA    
2523 C  C     . ALA A 314 ? 0.38098 0.27990 0.27402 -0.01666 -0.12135 0.03291  311 ALA A C     
2524 O  O     . ALA A 314 ? 0.41301 0.30696 0.30008 -0.01905 -0.13118 0.03890  311 ALA A O     
2525 C  CB    . ALA A 314 ? 0.34770 0.28376 0.29355 -0.01402 -0.11771 0.03298  311 ALA A CB    
2526 N  N     . ARG A 315 ? 0.38250 0.27613 0.26643 -0.01178 -0.10724 0.02748  312 ARG A N     
2527 C  CA    . ARG A 315 ? 0.42728 0.31017 0.29528 -0.00871 -0.10079 0.02810  312 ARG A CA    
2528 C  C     . ARG A 315 ? 0.42865 0.29484 0.27099 -0.00712 -0.09073 0.02226  312 ARG A C     
2529 O  O     . ARG A 315 ? 0.38880 0.25679 0.23310 -0.00631 -0.08558 0.01729  312 ARG A O     
2530 C  CB    . ARG A 315 ? 0.35887 0.25753 0.24973 -0.00317 -0.09145 0.02901  312 ARG A CB    
2531 C  CG    . ARG A 315 ? 0.33678 0.25014 0.25181 -0.00270 -0.09904 0.03515  312 ARG A CG    
2532 C  CD    . ARG A 315 ? 0.32678 0.25100 0.25953 0.00289  -0.08863 0.03500  312 ARG A CD    
2533 N  NE    . ARG A 315 ? 0.30338 0.23713 0.24798 0.00522  -0.07840 0.02909  312 ARG A NE    
2534 C  CZ    . ARG A 315 ? 0.31395 0.26185 0.27906 0.00564  -0.07945 0.02808  312 ARG A CZ    
2535 N  NH1   . ARG A 315 ? 0.30721 0.26334 0.28597 0.00433  -0.08916 0.03293  312 ARG A NH1   
2536 N  NH2   . ARG A 315 ? 0.29086 0.24534 0.26349 0.00746  -0.07049 0.02274  312 ARG A NH2   
2537 N  N     . ILE A 316 ? 0.41376 0.26396 0.23257 -0.00601 -0.08701 0.02333  313 ILE A N     
2538 C  CA    . ILE A 316 ? 0.47862 0.31356 0.27375 -0.00289 -0.07492 0.01882  313 ILE A CA    
2539 C  C     . ILE A 316 ? 0.49264 0.34027 0.30320 0.00289  -0.05992 0.01811  313 ILE A C     
2540 O  O     . ILE A 316 ? 0.45813 0.31013 0.27508 0.00388  -0.05841 0.02214  313 ILE A O     
2541 C  CB    . ILE A 316 ? 0.51433 0.32333 0.27295 -0.00477 -0.07795 0.02066  313 ILE A CB    
2542 C  CG1   . ILE A 316 ? 0.49208 0.28574 0.23209 -0.01164 -0.09364 0.02094  313 ILE A CG1   
2543 C  CG2   . ILE A 316 ? 0.50207 0.29754 0.23915 0.00033  -0.06217 0.01699  313 ILE A CG2   
2544 C  CD1   . ILE A 316 ? 0.52074 0.29035 0.22747 -0.01512 -0.10148 0.02454  313 ILE A CD1   
2545 N  N     . TYR A 317 ? 0.42793 0.28059 0.24369 0.00640  -0.04920 0.01347  314 TYR A N     
2546 C  CA    . TYR A 317 ? 0.41119 0.27682 0.24268 0.01090  -0.03598 0.01332  314 TYR A CA    
2547 C  C     . TYR A 317 ? 0.46961 0.32113 0.27822 0.01430  -0.02425 0.01349  314 TYR A C     
2548 O  O     . TYR A 317 ? 0.44828 0.28759 0.23882 0.01649  -0.01908 0.01019  314 TYR A O     
2549 C  CB    . TYR A 317 ? 0.39534 0.27675 0.24816 0.01299  -0.03084 0.00935  314 TYR A CB    
2550 C  CG    . TYR A 317 ? 0.45543 0.34972 0.32373 0.01661  -0.01851 0.00978  314 TYR A CG    
2551 C  CD1   . TYR A 317 ? 0.40314 0.30708 0.28642 0.01595  -0.01829 0.01329  314 TYR A CD1   
2552 C  CD2   . TYR A 317 ? 0.49854 0.39453 0.36604 0.02049  -0.00751 0.00726  314 TYR A CD2   
2553 C  CE1   . TYR A 317 ? 0.45376 0.36839 0.35039 0.01785  -0.00832 0.01412  314 TYR A CE1   
2554 C  CE2   . TYR A 317 ? 0.40999 0.31889 0.29295 0.02285  0.00250  0.00872  314 TYR A CE2   
2555 C  CZ    . TYR A 317 ? 0.40512 0.32310 0.30232 0.02091  0.00164  0.01205  314 TYR A CZ    
2556 O  OH    . TYR A 317 ? 0.59243 0.52233 0.50438 0.02194  0.01044  0.01383  314 TYR A OH    
2557 N  N     . ASP A 318 ? 0.48212 0.33475 0.29134 0.01503  -0.01948 0.01767  315 ASP A N     
2558 C  CA    . ASP A 318 ? 0.47474 0.31801 0.26727 0.01855  -0.00629 0.01913  315 ASP A CA    
2559 C  C     . ASP A 318 ? 0.51386 0.37572 0.32967 0.02201  0.00597  0.01858  315 ASP A C     
2560 O  O     . ASP A 318 ? 0.48374 0.36104 0.32220 0.02079  0.00649  0.02093  315 ASP A O     
2561 C  CB    . ASP A 318 ? 0.57749 0.41285 0.35961 0.01677  -0.00789 0.02469  315 ASP A CB    
2562 C  CG    . ASP A 318 ? 0.61848 0.44529 0.38463 0.02016  0.00665  0.02736  315 ASP A CG    
2563 O  OD1   . ASP A 318 ? 0.58285 0.41300 0.35015 0.02448  0.01909  0.02558  315 ASP A OD1   
2564 O  OD2   . ASP A 318 ? 0.72909 0.54534 0.48087 0.01868  0.00574  0.03191  315 ASP A OD2   
2565 N  N     . ASP A 319 ? 0.50384 0.36344 0.31365 0.02626  0.01544  0.01576  316 ASP A N     
2566 C  CA    . ASP A 319 ? 0.53769 0.41578 0.37042 0.02944  0.02581  0.01569  316 ASP A CA    
2567 C  C     . ASP A 319 ? 0.54238 0.42259 0.37394 0.03222  0.03948  0.02059  316 ASP A C     
2568 O  O     . ASP A 319 ? 0.59268 0.48671 0.44025 0.03531  0.04928  0.02152  316 ASP A O     
2569 C  CB    . ASP A 319 ? 0.50928 0.38610 0.33971 0.03321  0.02911  0.01105  316 ASP A CB    
2570 C  CG    . ASP A 319 ? 0.59489 0.44941 0.39342 0.03782  0.03678  0.01008  316 ASP A CG    
2571 O  OD1   . ASP A 319 ? 0.55743 0.39677 0.33395 0.03786  0.03936  0.01285  316 ASP A OD1   
2572 O  OD2   . ASP A 319 ? 0.54340 0.39410 0.33742 0.04178  0.04070  0.00656  316 ASP A OD2   
2573 N  N     . GLN A 320 ? 0.53226 0.39985 0.34619 0.03090  0.04005  0.02444  317 GLN A N     
2574 C  CA    . GLN A 320 ? 0.64416 0.51084 0.45279 0.03333  0.05360  0.02987  317 GLN A CA    
2575 C  C     . GLN A 320 ? 0.69370 0.55299 0.48773 0.04033  0.06745  0.02932  317 GLN A C     
2576 O  O     . GLN A 320 ? 0.73006 0.59449 0.52689 0.04355  0.08123  0.03427  317 GLN A O     
2577 C  CB    . GLN A 320 ? 0.66238 0.55159 0.50177 0.03112  0.05780  0.03399  317 GLN A CB    
2578 C  CG    . GLN A 320 ? 0.72638 0.62734 0.58753 0.02595  0.04553  0.03257  317 GLN A CG    
2579 C  CD    . GLN A 320 ? 0.85688 0.74764 0.70853 0.02201  0.03688  0.03519  317 GLN A CD    
2580 O  OE1   . GLN A 320 ? 0.93506 0.82315 0.78747 0.01982  0.02448  0.03274  317 GLN A OE1   
2581 N  NE2   . GLN A 320 ? 0.95839 0.84392 0.80187 0.02126  0.04357  0.04092  317 GLN A NE2   
2582 N  N     . GLY A 321 ? 0.68152 0.52823 0.45981 0.04286  0.06432  0.02382  318 GLY A N     
2583 C  CA    . GLY A 321 ? 0.64765 0.48486 0.41053 0.05052  0.07739  0.02273  318 GLY A CA    
2584 C  C     . GLY A 321 ? 0.71217 0.51984 0.43776 0.05151  0.07259  0.01807  318 GLY A C     
2585 O  O     . GLY A 321 ? 0.73157 0.52072 0.43269 0.04813  0.06658  0.01893  318 GLY A O     
2586 N  N     . ARG A 322 ? 0.64886 0.45076 0.36901 0.05557  0.07413  0.01324  319 ARG A N     
2587 C  CA    . ARG A 322 ? 0.69652 0.46704 0.37763 0.05746  0.07248  0.00890  319 ARG A CA    
2588 C  C     . ARG A 322 ? 0.72095 0.48365 0.39715 0.05024  0.05341  0.00394  319 ARG A C     
2589 O  O     . ARG A 322 ? 0.65938 0.40118 0.31184 0.05144  0.05096  -0.00074 319 ARG A O     
2590 C  CB    . ARG A 322 ? 0.74473 0.50939 0.41844 0.06721  0.08736  0.00711  319 ARG A CB    
2591 C  CG    . ARG A 322 ? 0.78982 0.56045 0.46575 0.07529  0.10769  0.01306  319 ARG A CG    
2592 C  CD    . ARG A 322 ? 0.85649 0.63344 0.54139 0.08508  0.12137  0.01266  319 ARG A CD    
2593 N  NE    . ARG A 322 ? 0.87943 0.62530 0.52831 0.09038  0.12367  0.00710  319 ARG A NE    
2594 C  CZ    . ARG A 322 ? 0.99819 0.74368 0.65041 0.09908  0.13362  0.00613  319 ARG A CZ    
2595 N  NH1   . ARG A 322 ? 0.86034 0.63430 0.54684 0.10416  0.14270  0.00994  319 ARG A NH1   
2596 N  NH2   . ARG A 322 ? 0.89687 0.61486 0.52282 0.10129  0.13164  0.00211  319 ARG A NH2   
2597 N  N     . TYR A 323 ? 0.59875 0.37713 0.29662 0.04280  0.04005  0.00530  320 TYR A N     
2598 C  CA    . TYR A 323 ? 0.62818 0.40428 0.32789 0.03619  0.02272  0.00176  320 TYR A CA    
2599 C  C     . TYR A 323 ? 0.66509 0.40941 0.32512 0.03261  0.01349  -0.00017 320 TYR A C     
2600 O  O     . TYR A 323 ? 0.61816 0.35320 0.27058 0.02898  0.00306  -0.00401 320 TYR A O     
2601 C  CB    . TYR A 323 ? 0.58568 0.38338 0.31458 0.03007  0.01174  0.00462  320 TYR A CB    
2602 C  CG    . TYR A 323 ? 0.57967 0.36799 0.29510 0.02604  0.00531  0.00882  320 TYR A CG    
2603 C  CD1   . TYR A 323 ? 0.59737 0.38689 0.31060 0.02864  0.01576  0.01334  320 TYR A CD1   
2604 C  CD2   . TYR A 323 ? 0.53784 0.31655 0.24349 0.01938  -0.01153 0.00901  320 TYR A CD2   
2605 C  CE1   . TYR A 323 ? 0.64489 0.42454 0.34449 0.02502  0.00977  0.01754  320 TYR A CE1   
2606 C  CE2   . TYR A 323 ? 0.66867 0.43862 0.36192 0.01592  -0.01817 0.01348  320 TYR A CE2   
2607 C  CZ    . TYR A 323 ? 0.70378 0.47351 0.39324 0.01891  -0.00739 0.01752  320 TYR A CZ    
2608 O  OH    . TYR A 323 ? 0.68499 0.44485 0.36101 0.01550  -0.01420 0.02227  320 TYR A OH    
2609 N  N     . GLN A 324 ? 0.65623 0.38258 0.28957 0.03299  0.01669  0.00267  321 GLN A N     
2610 C  CA    . GLN A 324 ? 0.70883 0.40253 0.30117 0.02900  0.00711  0.00097  321 GLN A CA    
2611 C  C     . GLN A 324 ? 0.77150 0.44087 0.33507 0.03376  0.01393  -0.00447 321 GLN A C     
2612 O  O     . GLN A 324 ? 0.72961 0.37982 0.27314 0.02861  0.00149  -0.00812 321 GLN A O     
2613 C  CB    . GLN A 324 ? 0.74056 0.41935 0.30891 0.02897  0.01043  0.00547  321 GLN A CB    
2614 C  CG    . GLN A 324 ? 0.75242 0.44994 0.34414 0.02350  0.00096  0.01091  321 GLN A CG    
2615 C  CD    . GLN A 324 ? 0.87484 0.55372 0.43862 0.02218  0.00106  0.01550  321 GLN A CD    
2616 O  OE1   . GLN A 324 ? 0.95820 0.61022 0.48448 0.02554  0.00930  0.01463  321 GLN A OE1   
2617 N  NE2   . GLN A 324 ? 0.85535 0.54704 0.43599 0.01761  -0.00793 0.02052  321 GLN A NE2   
2618 N  N     . GLU A 325 ? 0.77140 0.44158 0.33377 0.04361  0.03366  -0.00461 322 GLU A N     
2619 C  CA    . GLU A 325 ? 0.75342 0.40172 0.29118 0.05000  0.04221  -0.00953 322 GLU A CA    
2620 C  C     . GLU A 325 ? 0.79681 0.45570 0.35447 0.04781  0.03415  -0.01374 322 GLU A C     
2621 O  O     . GLU A 325 ? 0.77991 0.41662 0.31641 0.04680  0.02943  -0.01809 322 GLU A O     
2622 C  CB    . GLU A 325 ? 0.84238 0.49747 0.38634 0.06154  0.06531  -0.00697 322 GLU A CB    
2623 C  CG    . GLU A 325 ? 0.88238 0.52937 0.42423 0.06920  0.07482  -0.01009 322 GLU A CG    
2624 C  CD    . GLU A 325 ? 0.95391 0.61797 0.51435 0.08029  0.09610  -0.00593 322 GLU A CD    
2625 O  OE1   . GLU A 325 ? 0.95231 0.63241 0.52502 0.08132  0.10375  -0.00063 322 GLU A OE1   
2626 O  OE2   . GLU A 325 ? 1.03389 0.69632 0.59836 0.08755  0.10454  -0.00711 322 GLU A OE2   
2627 N  N     . GLY A 326 ? 0.71869 0.41255 0.32074 0.04644  0.03212  -0.01192 323 GLY A N     
2628 C  CA    . GLY A 326 ? 0.69748 0.40234 0.31912 0.04395  0.02432  -0.01536 323 GLY A CA    
2629 C  C     . GLY A 326 ? 0.70435 0.39556 0.31319 0.03361  0.00416  -0.01759 323 GLY A C     
2630 O  O     . GLY A 326 ? 0.71741 0.39623 0.31638 0.03206  -0.00091 -0.02171 323 GLY A O     
2631 N  N     . LEU A 327 ? 0.61745 0.31023 0.22603 0.02624  -0.00781 -0.01427 324 LEU A N     
2632 C  CA    . LEU A 327 ? 0.64816 0.32916 0.24566 0.01587  -0.02789 -0.01490 324 LEU A CA    
2633 C  C     . LEU A 327 ? 0.78125 0.42135 0.32940 0.01438  -0.03091 -0.01834 324 LEU A C     
2634 O  O     . LEU A 327 ? 0.71311 0.34273 0.25572 0.00740  -0.04358 -0.02025 324 LEU A O     
2635 C  CB    . LEU A 327 ? 0.65442 0.34741 0.26414 0.00951  -0.03918 -0.00950 324 LEU A CB    
2636 C  CG    . LEU A 327 ? 0.59698 0.32751 0.25370 0.00967  -0.03902 -0.00634 324 LEU A CG    
2637 C  CD1   . LEU A 327 ? 0.61870 0.35636 0.28292 0.00409  -0.05031 -0.00083 324 LEU A CD1   
2638 C  CD2   . LEU A 327 ? 0.56532 0.31194 0.24732 0.00675  -0.04575 -0.00850 324 LEU A CD2   
2639 N  N     . ARG A 328 ? 0.77545 0.39846 0.30066 0.02035  -0.01840 -0.01763 325 ARG A N     
2640 C  CA    . ARG A 328 ? 0.77927 0.37107 0.27491 0.01945  -0.01882 -0.01931 325 ARG A CA    
2641 C  C     . ARG A 328 ? 0.88926 0.47207 0.38181 0.02420  -0.01202 -0.02346 325 ARG A C     
2642 O  O     . ARG A 328 ? 0.90064 0.46265 0.37711 0.01879  -0.02126 -0.02512 325 ARG A O     
2643 C  CB    . ARG A 328 ? 0.80113 0.37898 0.27666 0.02579  -0.00529 -0.01720 325 ARG A CB    
2644 C  CG    . ARG A 328 ? 0.89665 0.46935 0.36249 0.01877  -0.01591 -0.01330 325 ARG A CG    
2645 C  CD    . ARG A 328 ? 0.92665 0.47856 0.36661 0.02427  -0.00343 -0.01200 325 ARG A CD    
2646 N  NE    . ARG A 328 ? 0.95794 0.52661 0.41023 0.03388  0.01562  -0.00943 325 ARG A NE    
2647 C  CZ    . ARG A 328 ? 0.91208 0.49707 0.37581 0.03304  0.01654  -0.00473 325 ARG A CZ    
2648 N  NH1   . ARG A 328 ? 0.92257 0.51022 0.38784 0.02388  -0.00051 -0.00202 325 ARG A NH1   
2649 N  NH2   . ARG A 328 ? 0.84448 0.44414 0.32002 0.04152  0.03490  -0.00182 325 ARG A NH2   
2650 N  N     . THR A 329 ? 0.79667 0.39499 0.30508 0.03420  0.00399  -0.02448 326 THR A N     
2651 C  CA    . THR A 329 ? 0.87913 0.47094 0.38728 0.03958  0.01082  -0.02764 326 THR A CA    
2652 C  C     . THR A 329 ? 0.88803 0.48464 0.40738 0.03100  -0.00507 -0.03007 326 THR A C     
2653 O  O     . THR A 329 ? 0.86070 0.43880 0.36694 0.02922  -0.00868 -0.03198 326 THR A O     
2654 C  CB    . THR A 329 ? 0.92165 0.53421 0.45056 0.05156  0.02999  -0.02706 326 THR A CB    
2655 O  OG1   . THR A 329 ? 0.89483 0.50075 0.41270 0.05972  0.04574  -0.02395 326 THR A OG1   
2656 C  CG2   . THR A 329 ? 0.91556 0.52569 0.44943 0.05686  0.03531  -0.02970 326 THR A CG2   
2657 N  N     . LEU A 330 ? 0.80582 0.42668 0.34912 0.02541  -0.01480 -0.02945 327 LEU A N     
2658 C  CA    . LEU A 330 ? 0.77585 0.40453 0.33357 0.01684  -0.03003 -0.03091 327 LEU A CA    
2659 C  C     . LEU A 330 ? 0.85328 0.46137 0.39362 0.00574  -0.04674 -0.02964 327 LEU A C     
2660 O  O     . LEU A 330 ? 0.89040 0.48985 0.42875 0.00133  -0.05344 -0.03105 327 LEU A O     
2661 C  CB    . LEU A 330 ? 0.70754 0.37149 0.30362 0.01308  -0.03645 -0.02770 327 LEU A CB    
2662 C  CG    . LEU A 330 ? 0.74556 0.43373 0.37609 0.00810  -0.04503 -0.02745 327 LEU A CG    
2663 C  CD1   . LEU A 330 ? 0.76870 0.45443 0.40133 0.01409  -0.03600 -0.03142 327 LEU A CD1   
2664 C  CD2   . LEU A 330 ? 0.69833 0.42339 0.37019 0.00887  -0.04338 -0.02320 327 LEU A CD2   
2665 N  N     . HIS A 331 ? 0.81424 0.41389 0.34183 0.00100  -0.05345 -0.02647 328 HIS A N     
2666 C  CA    . HIS A 331 ? 0.96306 0.54347 0.47480 -0.00984 -0.06956 -0.02454 328 HIS A CA    
2667 C  C     . HIS A 331 ? 0.98595 0.53341 0.46715 -0.00764 -0.06447 -0.02681 328 HIS A C     
2668 O  O     . HIS A 331 ? 0.96825 0.50246 0.44219 -0.01577 -0.07620 -0.02651 328 HIS A O     
2669 C  CB    . HIS A 331 ? 0.90449 0.48221 0.40841 -0.01412 -0.07635 -0.02053 328 HIS A CB    
2670 C  CG    . HIS A 331 ? 0.96867 0.53143 0.46177 -0.02619 -0.09463 -0.01756 328 HIS A CG    
2671 N  ND1   . HIS A 331 ? 0.98953 0.52241 0.45057 -0.02803 -0.09580 -0.01696 328 HIS A ND1   
2672 C  CD2   . HIS A 331 ? 1.00878 0.58265 0.51967 -0.03707 -0.11217 -0.01449 328 HIS A CD2   
2673 C  CE1   . HIS A 331 ? 1.02624 0.55187 0.48499 -0.03987 -0.11384 -0.01375 328 HIS A CE1   
2674 N  NE2   . HIS A 331 ? 1.07180 0.62298 0.56169 -0.04545 -0.12374 -0.01184 328 HIS A NE2   
2675 N  N     . ARG A 332 ? 1.02703 0.56081 0.49032 0.00329  -0.04690 -0.02835 329 ARG A N     
2676 C  CA    . ARG A 332 ? 1.09033 0.59118 0.52313 0.00623  -0.04159 -0.02994 329 ARG A CA    
2677 C  C     . ARG A 332 ? 1.15917 0.65976 0.59838 0.00829  -0.03948 -0.03239 329 ARG A C     
2678 O  O     . ARG A 332 ? 1.18915 0.66385 0.60672 0.00471  -0.04446 -0.03286 329 ARG A O     
2679 C  CB    . ARG A 332 ? 1.24304 0.73148 0.65807 0.01836  -0.02217 -0.03010 329 ARG A CB    
2680 C  CG    . ARG A 332 ? 1.25934 0.76669 0.69304 0.03120  -0.00339 -0.03118 329 ARG A CG    
2681 C  CD    . ARG A 332 ? 1.40658 0.89424 0.81911 0.04314  0.01535  -0.03086 329 ARG A CD    
2682 N  NE    . ARG A 332 ? 1.39478 0.90549 0.83037 0.05514  0.03303  -0.03032 329 ARG A NE    
2683 C  CZ    . ARG A 332 ? 1.37696 0.88826 0.81837 0.06227  0.04140  -0.03135 329 ARG A CZ    
2684 N  NH1   . ARG A 332 ? 1.46172 0.95016 0.88542 0.05917  0.03481  -0.03321 329 ARG A NH1   
2685 N  NH2   . ARG A 332 ? 1.34895 0.88459 0.81500 0.07250  0.05644  -0.02989 329 ARG A NH2   
2686 N  N     . ASP A 333 ? 1.00060 0.52856 0.46830 0.01369  -0.03262 -0.03374 330 ASP A N     
2687 C  CA    . ASP A 333 ? 0.93150 0.46050 0.40676 0.01556  -0.03095 -0.03588 330 ASP A CA    
2688 C  C     . ASP A 333 ? 0.98477 0.51856 0.47078 0.00253  -0.05004 -0.03530 330 ASP A C     
2689 O  O     . ASP A 333 ? 1.05291 0.58769 0.54564 0.00259  -0.05036 -0.03675 330 ASP A O     
2690 C  CB    . ASP A 333 ? 0.97604 0.53210 0.47821 0.02588  -0.01698 -0.03727 330 ASP A CB    
2691 C  CG    . ASP A 333 ? 1.02546 0.57687 0.51924 0.03969  0.00365  -0.03671 330 ASP A CG    
2692 O  OD1   . ASP A 333 ? 1.16410 0.68820 0.62893 0.04192  0.00774  -0.03593 330 ASP A OD1   
2693 O  OD2   . ASP A 333 ? 0.90635 0.48151 0.42302 0.04816  0.01575  -0.03651 330 ASP A OD2   
2694 N  N     . GLY A 334 ? 0.92130 0.45877 0.41023 -0.00852 -0.06570 -0.03247 331 GLY A N     
2695 C  CA    . GLY A 334 ? 0.94797 0.48677 0.44460 -0.02156 -0.08405 -0.03027 331 GLY A CA    
2696 C  C     . GLY A 334 ? 0.84031 0.41285 0.37258 -0.02810 -0.09452 -0.02806 331 GLY A C     
2697 O  O     . GLY A 334 ? 0.86210 0.43945 0.40517 -0.03893 -0.10935 -0.02511 331 GLY A O     
2698 N  N     . ALA A 335 ? 0.78871 0.38490 0.34014 -0.02190 -0.08719 -0.02877 332 ALA A N     
2699 C  CA    . ALA A 335 ? 0.75611 0.38282 0.33980 -0.02805 -0.09775 -0.02596 332 ALA A CA    
2700 C  C     . ALA A 335 ? 0.86068 0.48666 0.44263 -0.03725 -0.11198 -0.02060 332 ALA A C     
2701 O  O     . ALA A 335 ? 0.82258 0.43194 0.38234 -0.03533 -0.10915 -0.02000 332 ALA A O     
2702 C  CB    . ALA A 335 ? 0.76885 0.41826 0.37029 -0.01895 -0.08634 -0.02782 332 ALA A CB    
2703 N  N     . LYS A 336 ? 0.69301 0.33749 0.29945 -0.04702 -0.12691 -0.01610 333 LYS A N     
2704 C  CA    . LYS A 336 ? 0.71697 0.36864 0.33043 -0.05446 -0.13975 -0.00996 333 LYS A CA    
2705 C  C     . LYS A 336 ? 0.66422 0.34395 0.30216 -0.04974 -0.13680 -0.00852 333 LYS A C     
2706 O  O     . LYS A 336 ? 0.62917 0.33245 0.29369 -0.04783 -0.13512 -0.00917 333 LYS A O     
2707 C  CB    . LYS A 336 ? 0.83926 0.49808 0.46873 -0.06665 -0.15632 -0.00433 333 LYS A CB    
2708 C  CG    . LYS A 336 ? 0.95955 0.59003 0.56453 -0.07124 -0.15880 -0.00580 333 LYS A CG    
2709 C  CD    . LYS A 336 ? 1.03106 0.67458 0.65815 -0.07975 -0.16860 -0.00233 333 LYS A CD    
2710 C  CE    . LYS A 336 ? 0.95957 0.58393 0.57033 -0.07836 -0.16307 -0.00665 333 LYS A CE    
2711 N  NZ    . LYS A 336 ? 0.83446 0.46478 0.44823 -0.06647 -0.14684 -0.01340 333 LYS A NZ    
2712 N  N     . ILE A 337 ? 0.69308 0.36826 0.31986 -0.04721 -0.13508 -0.00677 334 ILE A N     
2713 C  CA    . ILE A 337 ? 0.71118 0.40967 0.35740 -0.04270 -0.13260 -0.00439 334 ILE A CA    
2714 C  C     . ILE A 337 ? 0.69759 0.40282 0.35237 -0.04965 -0.14623 0.00300  334 ILE A C     
2715 O  O     . ILE A 337 ? 0.67728 0.36093 0.30821 -0.05310 -0.15013 0.00428  334 ILE A O     
2716 C  CB    . ILE A 337 ? 0.71228 0.40093 0.33874 -0.03194 -0.11580 -0.00811 334 ILE A CB    
2717 C  CG1   . ILE A 337 ? 0.76587 0.44066 0.37742 -0.02467 -0.10120 -0.01500 334 ILE A CG1   
2718 C  CG2   . ILE A 337 ? 0.64440 0.36602 0.30796 -0.02609 -0.10772 -0.00458 334 ILE A CG2   
2719 C  CD1   . ILE A 337 ? 0.78541 0.46581 0.39902 -0.01251 -0.08042 -0.01662 334 ILE A CD1   
2720 N  N     . ALA A 338 ? 0.56496 0.29968 0.25403 -0.05124 -0.15309 0.00809  335 ALA A N     
2721 C  CA    . ALA A 338 ? 0.60878 0.35328 0.31111 -0.05693 -0.16553 0.01597  335 ALA A CA    
2722 C  C     . ALA A 338 ? 0.55862 0.33311 0.29316 -0.05238 -0.16497 0.02018  335 ALA A C     
2723 O  O     . ALA A 338 ? 0.54081 0.33544 0.30156 -0.04723 -0.15494 0.01779  335 ALA A O     
2724 C  CB    . ALA A 338 ? 0.57967 0.32744 0.29459 -0.06737 -0.17933 0.02049  335 ALA A CB    
2725 N  N     . MET A 339 ? 0.56498 0.34473 0.30470 -0.05289 -0.17047 0.02635  336 MET A N     
2726 C  CA    . MET A 339 ? 0.60942 0.41817 0.38458 -0.04827 -0.16872 0.03144  336 MET A CA    
2727 C  C     . MET A 339 ? 0.54853 0.37983 0.35645 -0.05409 -0.18114 0.03773  336 MET A C     
2728 O  O     . MET A 339 ? 0.57576 0.40154 0.38184 -0.06217 -0.19089 0.04085  336 MET A O     
2729 C  CB    . MET A 339 ? 0.52646 0.33002 0.29218 -0.04668 -0.17141 0.03647  336 MET A CB    
2730 C  CG    . MET A 339 ? 0.54376 0.32902 0.28213 -0.04013 -0.15670 0.03157  336 MET A CG    
2731 S  SD    . MET A 339 ? 0.54621 0.34102 0.29594 -0.03030 -0.13344 0.02354  336 MET A SD    
2732 C  CE    . MET A 339 ? 0.47815 0.30865 0.27548 -0.02529 -0.12913 0.02787  336 MET A CE    
2733 N  N     . MET A 340 ? 0.50562 0.36461 0.34983 -0.04873 -0.17410 0.03897  337 MET A N     
2734 C  CA    . MET A 340 ? 0.45532 0.33796 0.33293 -0.05278 -0.18402 0.04582  337 MET A CA    
2735 C  C     . MET A 340 ? 0.51048 0.39990 0.39900 -0.05529 -0.19314 0.05459  337 MET A C     
2736 O  O     . MET A 340 ? 0.49160 0.38127 0.37838 -0.05023 -0.19149 0.05712  337 MET A O     
2737 C  CB    . MET A 340 ? 0.39512 0.30354 0.30682 -0.04454 -0.17025 0.04444  337 MET A CB    
2738 C  CG    . MET A 340 ? 0.43243 0.33933 0.34249 -0.04308 -0.15985 0.03653  337 MET A CG    
2739 S  SD    . MET A 340 ? 0.40337 0.33835 0.35048 -0.03449 -0.14509 0.03498  337 MET A SD    
2740 C  CE    . MET A 340 ? 0.40324 0.36258 0.38493 -0.03923 -0.15670 0.04442  337 MET A CE    
2741 N  N     . ASN A 341 ? 0.49260 0.38719 0.39244 -0.06306 -0.20236 0.05957  338 ASN A N     
2742 C  CA    . ASN A 341 ? 0.56913 0.47402 0.48499 -0.06595 -0.21137 0.06876  338 ASN A CA    
2743 C  C     . ASN A 341 ? 0.48329 0.41977 0.44212 -0.06401 -0.21037 0.07498  338 ASN A C     
2744 O  O     . ASN A 341 ? 0.45592 0.40463 0.42994 -0.06069 -0.20279 0.07179  338 ASN A O     
2745 C  CB    . ASN A 341 ? 0.63368 0.51942 0.52895 -0.07662 -0.22280 0.07061  338 ASN A CB    
2746 C  CG    . ASN A 341 ? 0.78882 0.64597 0.64580 -0.07755 -0.22464 0.06760  338 ASN A CG    
2747 O  OD1   . ASN A 341 ? 0.76099 0.61903 0.61607 -0.07235 -0.22293 0.06965  338 ASN A OD1   
2748 N  ND2   . ASN A 341 ? 0.84740 0.67761 0.67256 -0.08391 -0.22744 0.06284  338 ASN A ND2   
2749 N  N     . TYR A 342 ? 0.52050 0.46960 0.49831 -0.06602 -0.21767 0.08407  339 TYR A N     
2750 C  CA    . TYR A 342 ? 0.45177 0.43045 0.46983 -0.06302 -0.21515 0.09070  339 TYR A CA    
2751 C  C     . TYR A 342 ? 0.49987 0.48563 0.52861 -0.06771 -0.21373 0.08929  339 TYR A C     
2752 O  O     . TYR A 342 ? 0.45874 0.46448 0.51297 -0.06217 -0.20497 0.08943  339 TYR A O     
2753 C  CB    . TYR A 342 ? 0.53072 0.51901 0.56409 -0.06603 -0.22456 0.10113  339 TYR A CB    
2754 C  CG    . TYR A 342 ? 0.53192 0.54995 0.60590 -0.06271 -0.22127 0.10874  339 TYR A CG    
2755 C  CD1   . TYR A 342 ? 0.60459 0.63205 0.69277 -0.06892 -0.22325 0.11145  339 TYR A CD1   
2756 C  CD2   . TYR A 342 ? 0.64958 0.68488 0.74638 -0.05285 -0.21527 0.11333  339 TYR A CD2   
2757 C  CE1   . TYR A 342 ? 0.55130 0.60507 0.67500 -0.06537 -0.21889 0.11856  339 TYR A CE1   
2758 C  CE2   . TYR A 342 ? 0.64905 0.70973 0.78081 -0.04878 -0.21060 0.12002  339 TYR A CE2   
2759 C  CZ    . TYR A 342 ? 0.63130 0.70140 0.77629 -0.05507 -0.21223 0.12266  339 TYR A CZ    
2760 O  OH    . TYR A 342 ? 0.80080 0.89546 0.97929 -0.05082 -0.20669 0.12965  339 TYR A OH    
2761 N  N     . SER A 343 ? 0.52731 0.49582 0.53616 -0.07787 -0.22200 0.08818  340 SER A N     
2762 C  CA    . SER A 343 ? 0.49961 0.47443 0.51910 -0.08310 -0.22176 0.08827  340 SER A CA    
2763 C  C     . SER A 343 ? 0.48702 0.46258 0.50479 -0.07770 -0.21030 0.07962  340 SER A C     
2764 O  O     . SER A 343 ? 0.45490 0.44689 0.49459 -0.07720 -0.20543 0.08068  340 SER A O     
2765 C  CB    . SER A 343 ? 0.60118 0.55308 0.59558 -0.09497 -0.23294 0.08840  340 SER A CB    
2766 O  OG    . SER A 343 ? 0.83088 0.75377 0.78726 -0.09612 -0.23542 0.08236  340 SER A OG    
2767 N  N     . GLU A 344 ? 0.46998 0.42778 0.46165 -0.07359 -0.20568 0.07134  341 GLU A N     
2768 C  CA    . GLU A 344 ? 0.45495 0.41277 0.44411 -0.06851 -0.19539 0.06325  341 GLU A CA    
2769 C  C     . GLU A 344 ? 0.44911 0.43140 0.46765 -0.05856 -0.18566 0.06443  341 GLU A C     
2770 O  O     . GLU A 344 ? 0.37670 0.37005 0.40917 -0.05566 -0.17805 0.06144  341 GLU A O     
2771 C  CB    . GLU A 344 ? 0.47590 0.40616 0.42679 -0.06708 -0.19317 0.05462  341 GLU A CB    
2772 C  CG    . GLU A 344 ? 0.50939 0.41203 0.42828 -0.07574 -0.19956 0.05145  341 GLU A CG    
2773 C  CD    . GLU A 344 ? 0.59900 0.48736 0.50174 -0.08127 -0.20972 0.05612  341 GLU A CD    
2774 O  OE1   . GLU A 344 ? 0.60250 0.49051 0.50156 -0.07684 -0.20940 0.05768  341 GLU A OE1   
2775 O  OE2   . GLU A 344 ? 0.58201 0.45833 0.47476 -0.09032 -0.21833 0.05844  341 GLU A OE2   
2776 N  N     . PHE A 345 ? 0.41693 0.40648 0.44416 -0.05304 -0.18539 0.06871  342 PHE A N     
2777 C  CA    . PHE A 345 ? 0.39638 0.40798 0.45222 -0.04337 -0.17589 0.07063  342 PHE A CA    
2778 C  C     . PHE A 345 ? 0.40672 0.44144 0.49493 -0.04388 -0.17366 0.07662  342 PHE A C     
2779 O  O     . PHE A 345 ? 0.37585 0.42476 0.48251 -0.03831 -0.16377 0.07488  342 PHE A O     
2780 C  CB    . PHE A 345 ? 0.34921 0.36223 0.40736 -0.03761 -0.17653 0.07495  342 PHE A CB    
2781 C  CG    . PHE A 345 ? 0.33351 0.32608 0.36245 -0.03498 -0.17575 0.06955  342 PHE A CG    
2782 C  CD1   . PHE A 345 ? 0.34822 0.33721 0.37155 -0.02831 -0.15998 0.06062  342 PHE A CD1   
2783 C  CD2   . PHE A 345 ? 0.41975 0.39533 0.42584 -0.03850 -0.18360 0.07157  342 PHE A CD2   
2784 C  CE1   . PHE A 345 ? 0.34451 0.31500 0.34175 -0.02542 -0.15338 0.05484  342 PHE A CE1   
2785 C  CE2   . PHE A 345 ? 0.42855 0.38448 0.40642 -0.03561 -0.17996 0.06664  342 PHE A CE2   
2786 C  CZ    . PHE A 345 ? 0.35956 0.31359 0.33412 -0.02886 -0.16276 0.05787  342 PHE A CZ    
2787 N  N     . GLU A 346 ? 0.40327 0.44144 0.49810 -0.05052 -0.18256 0.08407  343 GLU A N     
2788 C  CA    . GLU A 346 ? 0.38949 0.44906 0.51404 -0.05134 -0.18062 0.09081  343 GLU A CA    
2789 C  C     . GLU A 346 ? 0.41470 0.47468 0.53958 -0.05509 -0.17690 0.08659  343 GLU A C     
2790 O  O     . GLU A 346 ? 0.39863 0.47664 0.54691 -0.05079 -0.16807 0.08812  343 GLU A O     
2791 C  CB    . GLU A 346 ? 0.46127 0.52207 0.59003 -0.05925 -0.19258 0.09986  343 GLU A CB    
2792 C  CG    . GLU A 346 ? 0.47254 0.55549 0.63196 -0.06055 -0.19111 0.10811  343 GLU A CG    
2793 C  CD    . GLU A 346 ? 0.56928 0.65482 0.73495 -0.06811 -0.20353 0.11820  343 GLU A CD    
2794 O  OE1   . GLU A 346 ? 0.63465 0.70128 0.77741 -0.07806 -0.21509 0.11763  343 GLU A OE1   
2795 O  OE2   . GLU A 346 ? 0.65321 0.75876 0.84593 -0.06398 -0.20163 0.12680  343 GLU A OE2   
2796 N  N     . TYR A 347 ? 0.41339 0.45200 0.51072 -0.06272 -0.18296 0.08112  344 TYR A N     
2797 C  CA    . TYR A 347 ? 0.38769 0.42385 0.48247 -0.06667 -0.18016 0.07698  344 TYR A CA    
2798 C  C     . TYR A 347 ? 0.42659 0.47080 0.52920 -0.05810 -0.16742 0.07058  344 TYR A C     
2799 O  O     . TYR A 347 ? 0.39871 0.45571 0.51822 -0.05749 -0.16118 0.07106  344 TYR A O     
2800 C  CB    . TYR A 347 ? 0.40247 0.41012 0.46191 -0.07486 -0.18788 0.07133  344 TYR A CB    
2801 C  CG    . TYR A 347 ? 0.44456 0.44657 0.49811 -0.07830 -0.18470 0.06630  344 TYR A CG    
2802 C  CD1   . TYR A 347 ? 0.50128 0.50900 0.56589 -0.08579 -0.18883 0.07169  344 TYR A CD1   
2803 C  CD2   . TYR A 347 ? 0.49595 0.48753 0.53388 -0.07384 -0.17744 0.05669  344 TYR A CD2   
2804 C  CE1   . TYR A 347 ? 0.46181 0.46380 0.52081 -0.08885 -0.18586 0.06741  344 TYR A CE1   
2805 C  CE2   . TYR A 347 ? 0.48415 0.47036 0.51696 -0.07660 -0.17441 0.05223  344 TYR A CE2   
2806 C  CZ    . TYR A 347 ? 0.59214 0.58319 0.63515 -0.08409 -0.17859 0.05754  344 TYR A CZ    
2807 O  OH    . TYR A 347 ? 0.60892 0.59356 0.64601 -0.08686 -0.17566 0.05337  344 TYR A OH    
2808 N  N     . CYS A 348 ? 0.40505 0.44149 0.49524 -0.05160 -0.16353 0.06493  345 CYS A N     
2809 C  CA    . CYS A 348 ? 0.31620 0.35899 0.41298 -0.04382 -0.15231 0.05899  345 CYS A CA    
2810 C  C     . CYS A 348 ? 0.36281 0.42988 0.49194 -0.03594 -0.14292 0.06380  345 CYS A C     
2811 O  O     . CYS A 348 ? 0.35542 0.43213 0.49695 -0.03221 -0.13367 0.06121  345 CYS A O     
2812 C  CB    . CYS A 348 ? 0.34468 0.37073 0.41790 -0.03797 -0.14584 0.05143  345 CYS A CB    
2813 S  SG    . CYS A 348 ? 0.39925 0.39409 0.43097 -0.04353 -0.14884 0.04294  345 CYS A SG    
2814 N  N     . TRP A 349 ? 0.35834 0.43393 0.49973 -0.03283 -0.14450 0.07060  346 TRP A N     
2815 C  CA    . TRP A 349 ? 0.37959 0.47610 0.54970 -0.02520 -0.13511 0.07560  346 TRP A CA    
2816 C  C     . TRP A 349 ? 0.37200 0.48101 0.55848 -0.02911 -0.13290 0.07931  346 TRP A C     
2817 O  O     . TRP A 349 ? 0.33705 0.45722 0.53792 -0.02362 -0.12179 0.07808  346 TRP A O     
2818 C  CB    . TRP A 349 ? 0.34845 0.45036 0.52746 -0.02234 -0.13885 0.08309  346 TRP A CB    
2819 C  CG    . TRP A 349 ? 0.32621 0.44775 0.53292 -0.01431 -0.12924 0.08874  346 TRP A CG    
2820 C  CD1   . TRP A 349 ? 0.33685 0.47308 0.56339 -0.01641 -0.12965 0.09661  346 TRP A CD1   
2821 C  CD2   . TRP A 349 ? 0.33100 0.45782 0.54695 -0.00273 -0.11725 0.08691  346 TRP A CD2   
2822 N  NE1   . TRP A 349 ? 0.35574 0.50583 0.60238 -0.00632 -0.11818 0.09962  346 TRP A NE1   
2823 C  CE2   . TRP A 349 ? 0.32357 0.46715 0.56315 0.00215  -0.11040 0.09346  346 TRP A CE2   
2824 C  CE3   . TRP A 349 ? 0.32102 0.43878 0.52680 0.00391  -0.11168 0.08065  346 TRP A CE3   
2825 C  CZ2   . TRP A 349 ? 0.31876 0.46821 0.56945 0.01364  -0.09786 0.09319  346 TRP A CZ2   
2826 C  CZ3   . TRP A 349 ? 0.32635 0.45036 0.54442 0.01469  -0.09972 0.08064  346 TRP A CZ3   
2827 C  CH2   . TRP A 349 ? 0.32522 0.46394 0.56422 0.01958  -0.09278 0.08651  346 TRP A CH2   
2828 N  N     . ASP A 350 ? 0.35172 0.45736 0.53443 -0.03897 -0.14347 0.08389  347 ASP A N     
2829 C  CA    . ASP A 350 ? 0.37051 0.48796 0.56931 -0.04346 -0.14250 0.08892  347 ASP A CA    
2830 C  C     . ASP A 350 ? 0.45422 0.56772 0.64688 -0.04530 -0.13718 0.08233  347 ASP A C     
2831 O  O     . ASP A 350 ? 0.49874 0.62561 0.70869 -0.04434 -0.13029 0.08515  347 ASP A O     
2832 C  CB    . ASP A 350 ? 0.38446 0.49665 0.57852 -0.05448 -0.15631 0.09545  347 ASP A CB    
2833 C  CG    . ASP A 350 ? 0.46007 0.58175 0.66787 -0.05302 -0.16111 0.10450  347 ASP A CG    
2834 O  OD1   . ASP A 350 ? 0.41026 0.54552 0.63547 -0.04315 -0.15246 0.10687  347 ASP A OD1   
2835 O  OD2   . ASP A 350 ? 0.45530 0.56970 0.65559 -0.06180 -0.17368 0.10935  347 ASP A OD2   
2836 N  N     . THR A 351 ? 0.38594 0.48098 0.55388 -0.04761 -0.13988 0.07383  348 THR A N     
2837 C  CA    . THR A 351 ? 0.36601 0.45412 0.52483 -0.05092 -0.13721 0.06780  348 THR A CA    
2838 C  C     . THR A 351 ? 0.35795 0.44969 0.51972 -0.04232 -0.12540 0.06096  348 THR A C     
2839 O  O     . THR A 351 ? 0.39101 0.48933 0.56119 -0.04192 -0.11861 0.05967  348 THR A O     
2840 C  CB    . THR A 351 ? 0.38177 0.44470 0.50915 -0.05894 -0.14721 0.06246  348 THR A CB    
2841 O  OG1   . THR A 351 ? 0.43310 0.49006 0.55529 -0.06735 -0.15872 0.06872  348 THR A OG1   
2842 C  CG2   . THR A 351 ? 0.41510 0.46987 0.53307 -0.06278 -0.14502 0.05702  348 THR A CG2   
2843 N  N     . PHE A 352 ? 0.33355 0.41933 0.48659 -0.03549 -0.12201 0.05639  349 PHE A N     
2844 C  CA    . PHE A 352 ? 0.32492 0.40481 0.46884 -0.02757 -0.10765 0.04716  349 PHE A CA    
2845 C  C     . PHE A 352 ? 0.36469 0.45771 0.52594 -0.01739 -0.09661 0.04819  349 PHE A C     
2846 O  O     . PHE A 352 ? 0.34277 0.43197 0.49812 -0.01142 -0.08520 0.04122  349 PHE A O     
2847 C  CB    . PHE A 352 ? 0.29876 0.35667 0.41293 -0.02697 -0.10778 0.03917  349 PHE A CB    
2848 C  CG    . PHE A 352 ? 0.32510 0.36507 0.41670 -0.03574 -0.11723 0.03692  349 PHE A CG    
2849 C  CD1   . PHE A 352 ? 0.36283 0.39469 0.44446 -0.03788 -0.11350 0.03164  349 PHE A CD1   
2850 C  CD2   . PHE A 352 ? 0.40120 0.43036 0.47953 -0.04162 -0.12981 0.04000  349 PHE A CD2   
2851 C  CE1   . PHE A 352 ? 0.34350 0.35595 0.40214 -0.04537 -0.12165 0.02929  349 PHE A CE1   
2852 C  CE2   . PHE A 352 ? 0.47233 0.48138 0.52623 -0.04966 -0.13836 0.03745  349 PHE A CE2   
2853 C  CZ    . PHE A 352 ? 0.45678 0.45706 0.50076 -0.05131 -0.13393 0.03195  349 PHE A CZ    
2854 N  N     . VAL A 353 ? 0.32383 0.43134 0.50571 -0.01522 -0.09983 0.05690  350 VAL A N     
2855 C  CA    . VAL A 353 ? 0.30244 0.41813 0.49687 -0.00492 -0.09002 0.05785  350 VAL A CA    
2856 C  C     . VAL A 353 ? 0.32083 0.45524 0.54062 -0.00130 -0.08272 0.06382  350 VAL A C     
2857 O  O     . VAL A 353 ? 0.32469 0.46666 0.55336 -0.00673 -0.08677 0.07001  350 VAL A O     
2858 C  CB    . VAL A 353 ? 0.33337 0.44834 0.52893 -0.00309 -0.09717 0.06293  350 VAL A CB    
2859 C  CG1   . VAL A 353 ? 0.30661 0.42930 0.51601 0.00783  -0.08709 0.06473  350 VAL A CG1   
2860 C  CG2   . VAL A 353 ? 0.26685 0.36079 0.43340 -0.00572 -0.10127 0.05612  350 VAL A CG2   
2861 N  N     . ASP A 354 ? 0.34663 0.48409 0.57202 0.00785  -0.06974 0.06070  351 ASP A N     
2862 C  CA    . ASP A 354 ? 0.36522 0.51540 0.60781 0.01341  -0.05902 0.06476  351 ASP A CA    
2863 C  C     . ASP A 354 ? 0.38598 0.54316 0.64020 0.01788  -0.05934 0.07215  351 ASP A C     
2864 O  O     . ASP A 354 ? 0.42618 0.58280 0.68336 0.02715  -0.05110 0.07166  351 ASP A O     
2865 C  CB    . ASP A 354 ? 0.33588 0.48290 0.57610 0.02155  -0.04574 0.05831  351 ASP A CB    
2866 C  CG    . ASP A 354 ? 0.45093 0.60754 0.70336 0.02639  -0.03400 0.06117  351 ASP A CG    
2867 O  OD1   . ASP A 354 ? 0.43574 0.60267 0.69951 0.02226  -0.03625 0.06786  351 ASP A OD1   
2868 O  OD2   . ASP A 354 ? 0.49567 0.64824 0.74518 0.03418  -0.02254 0.05676  351 ASP A OD2   
2869 N  N     . ARG A 355 ? 0.39292 0.55584 0.65337 0.01098  -0.06928 0.07932  352 ARG A N     
2870 C  CA    . ARG A 355 ? 0.41021 0.57941 0.68132 0.01404  -0.07208 0.08694  352 ARG A CA    
2871 C  C     . ARG A 355 ? 0.52049 0.70415 0.81178 0.01995  -0.06251 0.09356  352 ARG A C     
2872 O  O     . ARG A 355 ? 0.47158 0.66056 0.77282 0.02512  -0.06200 0.09945  352 ARG A O     
2873 C  CB    . ARG A 355 ? 0.36245 0.53047 0.63075 0.00381  -0.08765 0.09223  352 ARG A CB    
2874 C  CG    . ARG A 355 ? 0.41496 0.58465 0.68287 -0.00645 -0.09335 0.09353  352 ARG A CG    
2875 C  CD    . ARG A 355 ? 0.33180 0.49389 0.58961 -0.01704 -0.10938 0.09663  352 ARG A CD    
2876 N  NE    . ARG A 355 ? 0.41614 0.58333 0.68025 -0.02634 -0.11507 0.10188  352 ARG A NE    
2877 C  CZ    . ARG A 355 ? 0.52170 0.70138 0.80344 -0.02887 -0.11863 0.11204  352 ARG A CZ    
2878 N  NH1   . ARG A 355 ? 0.60972 0.79834 0.90477 -0.02267 -0.11734 0.11817  352 ARG A NH1   
2879 N  NH2   . ARG A 355 ? 0.54073 0.72367 0.82692 -0.03798 -0.12398 0.11657  352 ARG A NH2   
2880 N  N     . GLN A 356 ? 0.48316 0.67280 0.78030 0.01949  -0.05493 0.09311  353 GLN A N     
2881 C  CA    . GLN A 356 ? 0.49530 0.69851 0.81102 0.02448  -0.04569 0.10003  353 GLN A CA    
2882 C  C     . GLN A 356 ? 0.49786 0.71231 0.82912 0.02067  -0.05429 0.11103  353 GLN A C     
2883 O  O     . GLN A 356 ? 0.53199 0.75411 0.87630 0.02799  -0.04952 0.11705  353 GLN A O     
2884 C  CB    . GLN A 356 ? 0.48226 0.68319 0.79877 0.03745  -0.03156 0.09738  353 GLN A CB    
2885 C  CG    . GLN A 356 ? 0.56568 0.75399 0.86585 0.04121  -0.02374 0.08669  353 GLN A CG    
2886 C  CD    . GLN A 356 ? 0.76372 0.95509 1.06507 0.04099  -0.01449 0.08472  353 GLN A CD    
2887 O  OE1   . GLN A 356 ? 0.75572 0.94288 1.04830 0.03463  -0.01755 0.07984  353 GLN A OE1   
2888 N  NE2   . GLN A 356 ? 0.79085 0.98895 1.10255 0.04817  -0.00291 0.08878  353 GLN A NE2   
2889 N  N     . GLY A 357 ? 0.52242 0.73650 0.85112 0.00894  -0.06759 0.11369  354 GLY A N     
2890 C  CA    . GLY A 357 ? 0.55973 0.78331 0.90177 0.00323  -0.07764 0.12429  354 GLY A CA    
2891 C  C     . GLY A 357 ? 0.54899 0.76947 0.88933 0.00464  -0.08585 0.12721  354 GLY A C     
2892 O  O     . GLY A 357 ? 0.58297 0.80845 0.93044 -0.00228 -0.09721 0.13535  354 GLY A O     
2893 N  N     . ARG A 358 ? 0.51088 0.72274 0.84172 0.01300  -0.08091 0.12126  355 ARG A N     
2894 C  CA    . ARG A 358 ? 0.52370 0.73237 0.85297 0.01506  -0.08807 0.12443  355 ARG A CA    
2895 C  C     . ARG A 358 ? 0.44334 0.64082 0.75619 0.00389  -0.10431 0.12323  355 ARG A C     
2896 O  O     . ARG A 358 ? 0.48160 0.66760 0.77705 -0.00151 -0.10701 0.11556  355 ARG A O     
2897 C  CB    . ARG A 358 ? 0.45166 0.65134 0.77226 0.02607  -0.07898 0.11785  355 ARG A CB    
2898 C  CG    . ARG A 358 ? 0.55687 0.76422 0.89100 0.03802  -0.06354 0.11959  355 ARG A CG    
2899 C  CD    . ARG A 358 ? 0.64770 0.84687 0.97666 0.04812  -0.05903 0.11754  355 ARG A CD    
2900 N  NE    . ARG A 358 ? 0.70411 0.90719 1.04262 0.05978  -0.04389 0.11850  355 ARG A NE    
2901 C  CZ    . ARG A 358 ? 0.63398 0.84827 0.99029 0.06542  -0.04070 0.12747  355 ARG A CZ    
2902 N  NH1   . ARG A 358 ? 0.57528 0.79925 0.94345 0.06044  -0.05191 0.13673  355 ARG A NH1   
2903 N  NH2   . ARG A 358 ? 0.64076 0.85581 1.00243 0.07631  -0.02592 0.12734  355 ARG A NH2   
2904 N  N     . PRO A 359 ? 0.53477 0.73415 0.85146 0.00040  -0.11521 0.13065  356 PRO A N     
2905 C  CA    . PRO A 359 ? 0.47478 0.66100 0.77299 -0.01038 -0.13075 0.12961  356 PRO A CA    
2906 C  C     . PRO A 359 ? 0.40367 0.57357 0.68075 -0.00703 -0.13220 0.12221  356 PRO A C     
2907 O  O     . PRO A 359 ? 0.39299 0.56258 0.67174 0.00347  -0.12261 0.11931  356 PRO A O     
2908 C  CB    . PRO A 359 ? 0.40193 0.59740 0.71410 -0.01427 -0.14074 0.14124  356 PRO A CB    
2909 C  CG    . PRO A 359 ? 0.48761 0.69550 0.81888 -0.00178 -0.13036 0.14587  356 PRO A CG    
2910 C  CD    . PRO A 359 ? 0.48284 0.69553 0.82007 0.00641  -0.11378 0.14054  356 PRO A CD    
2911 N  N     . PHE A 360 ? 0.35310 0.50783 0.60875 -0.01636 -0.14441 0.11937  357 PHE A N     
2912 C  CA    . PHE A 360 ? 0.42746 0.56525 0.66072 -0.01452 -0.14700 0.11299  357 PHE A CA    
2913 C  C     . PHE A 360 ? 0.42393 0.56301 0.66161 -0.00947 -0.15021 0.11888  357 PHE A C     
2914 O  O     . PHE A 360 ? 0.45535 0.59754 0.69775 -0.01486 -0.16047 0.12670  357 PHE A O     
2915 C  CB    . PHE A 360 ? 0.44889 0.56849 0.65612 -0.02583 -0.15900 0.10896  357 PHE A CB    
2916 C  CG    . PHE A 360 ? 0.40965 0.51067 0.59191 -0.02448 -0.16211 0.10320  357 PHE A CG    
2917 C  CD1   . PHE A 360 ? 0.40718 0.50416 0.58409 -0.01640 -0.15220 0.09611  357 PHE A CD1   
2918 C  CD2   . PHE A 360 ? 0.40386 0.49083 0.56753 -0.03136 -0.17480 0.10532  357 PHE A CD2   
2919 C  CE1   . PHE A 360 ? 0.41579 0.49579 0.57002 -0.01522 -0.15488 0.09169  357 PHE A CE1   
2920 C  CE2   . PHE A 360 ? 0.43900 0.50796 0.57810 -0.02993 -0.17692 0.10040  357 PHE A CE2   
2921 C  CZ    . PHE A 360 ? 0.40285 0.46876 0.53768 -0.02180 -0.16692 0.09387  357 PHE A CZ    
2922 N  N     . GLN A 361 ? 0.41435 0.55020 0.65008 0.00063  -0.14179 0.11538  358 GLN A N     
2923 C  CA    . GLN A 361 ? 0.45400 0.58857 0.69148 0.00642  -0.14392 0.12017  358 GLN A CA    
2924 C  C     . GLN A 361 ? 0.40492 0.51930 0.61538 0.00481  -0.14936 0.11474  358 GLN A C     
2925 O  O     . GLN A 361 ? 0.41999 0.52686 0.62214 0.01081  -0.14124 0.10811  358 GLN A O     
2926 C  CB    . GLN A 361 ? 0.44899 0.59292 0.70356 0.01963  -0.12973 0.12096  358 GLN A CB    
2927 C  CG    . GLN A 361 ? 0.63759 0.78039 0.89553 0.02660  -0.13109 0.12649  358 GLN A CG    
2928 C  CD    . GLN A 361 ? 0.74369 0.89460 1.01153 0.02124  -0.14282 0.13665  358 GLN A CD    
2929 O  OE1   . GLN A 361 ? 0.74590 0.88652 0.99911 0.01533  -0.15485 0.13844  358 GLN A OE1   
2930 N  NE2   . GLN A 361 ? 0.74695 0.91592 1.03925 0.02310  -0.13932 0.14368  358 GLN A NE2   
2931 N  N     . PRO A 362 ? 0.47260 0.57668 0.66774 -0.00329 -0.16278 0.11746  359 PRO A N     
2932 C  CA    . PRO A 362 ? 0.41031 0.49304 0.57603 -0.00559 -0.16753 0.11194  359 PRO A CA    
2933 C  C     . PRO A 362 ? 0.49375 0.57187 0.65774 0.00413  -0.16237 0.11249  359 PRO A C     
2934 O  O     . PRO A 362 ? 0.42284 0.51045 0.60323 0.01009  -0.16107 0.11925  359 PRO A O     
2935 C  CB    . PRO A 362 ? 0.49700 0.57052 0.64852 -0.01627 -0.18270 0.11611  359 PRO A CB    
2936 C  CG    . PRO A 362 ? 0.53342 0.62536 0.71135 -0.01615 -0.18583 0.12617  359 PRO A CG    
2937 C  CD    . PRO A 362 ? 0.46774 0.57818 0.67078 -0.01085 -0.17413 0.12603  359 PRO A CD    
2938 N  N     . TRP A 363 ? 0.48952 0.55224 0.63320 0.00582  -0.15925 0.10561  360 TRP A N     
2939 C  CA    . TRP A 363 ? 0.48089 0.53525 0.61878 0.01373  -0.15518 0.10608  360 TRP A CA    
2940 C  C     . TRP A 363 ? 0.50137 0.54377 0.62262 0.00977  -0.16632 0.11090  360 TRP A C     
2941 O  O     . TRP A 363 ? 0.45136 0.48701 0.55867 0.00018  -0.17701 0.11162  360 TRP A O     
2942 C  CB    . TRP A 363 ? 0.47233 0.51347 0.59357 0.01587  -0.14882 0.09797  360 TRP A CB    
2943 C  CG    . TRP A 363 ? 0.41538 0.44301 0.51144 0.00656  -0.15430 0.09191  360 TRP A CG    
2944 C  CD1   . TRP A 363 ? 0.43648 0.44456 0.50305 0.00087  -0.16164 0.09072  360 TRP A CD1   
2945 C  CD2   . TRP A 363 ? 0.45223 0.48277 0.54769 0.00222  -0.15071 0.08534  360 TRP A CD2   
2946 N  NE1   . TRP A 363 ? 0.43181 0.42979 0.47912 -0.00618 -0.16224 0.08358  360 TRP A NE1   
2947 C  CE2   . TRP A 363 ? 0.38593 0.39756 0.45094 -0.00558 -0.15598 0.08029  360 TRP A CE2   
2948 C  CE3   . TRP A 363 ? 0.36355 0.40963 0.48002 0.00448  -0.14315 0.08342  360 TRP A CE3   
2949 C  CZ2   . TRP A 363 ? 0.37424 0.38198 0.42998 -0.01084 -0.15416 0.07347  360 TRP A CZ2   
2950 C  CZ3   . TRP A 363 ? 0.37881 0.42168 0.48627 -0.00139 -0.14186 0.07682  360 TRP A CZ3   
2951 C  CH2   . TRP A 363 ? 0.42986 0.45367 0.50760 -0.00880 -0.14744 0.07195  360 TRP A CH2   
2952 N  N     . ASP A 364 ? 0.50991 0.54806 0.63139 0.01718  -0.16350 0.11411  361 ASP A N     
2953 C  CA    . ASP A 364 ? 0.54311 0.56930 0.64843 0.01436  -0.17311 0.11890  361 ASP A CA    
2954 C  C     . ASP A 364 ? 0.46090 0.46502 0.53148 0.00643  -0.17912 0.11379  361 ASP A C     
2955 O  O     . ASP A 364 ? 0.46717 0.46092 0.52366 0.00755  -0.17294 0.10713  361 ASP A O     
2956 C  CB    . ASP A 364 ? 0.64798 0.67026 0.75647 0.02421  -0.16738 0.12218  361 ASP A CB    
2957 C  CG    . ASP A 364 ? 0.70145 0.74229 0.84023 0.03251  -0.16253 0.12840  361 ASP A CG    
2958 O  OD1   . ASP A 364 ? 0.76349 0.81922 0.91855 0.02920  -0.16774 0.13322  361 ASP A OD1   
2959 O  OD2   . ASP A 364 ? 0.74687 0.78600 0.89207 0.04234  -0.15330 0.12868  361 ASP A OD2   
2960 N  N     . GLY A 365 ? 0.47272 0.46871 0.52863 -0.00142 -0.19088 0.11709  362 GLY A N     
2961 C  CA    . GLY A 365 ? 0.48254 0.45467 0.50193 -0.00846 -0.19613 0.11272  362 GLY A CA    
2962 C  C     . GLY A 365 ? 0.53594 0.50115 0.54079 -0.01564 -0.19681 0.10541  362 GLY A C     
2963 O  O     . GLY A 365 ? 0.47131 0.41487 0.44371 -0.01947 -0.19754 0.10029  362 GLY A O     
2964 N  N     . LEU A 366 ? 0.49295 0.47488 0.51967 -0.01731 -0.19580 0.10486  363 LEU A N     
2965 C  CA    . LEU A 366 ? 0.47698 0.45233 0.49097 -0.02342 -0.19547 0.09771  363 LEU A CA    
2966 C  C     . LEU A 366 ? 0.48073 0.43432 0.46276 -0.03350 -0.20545 0.09596  363 LEU A C     
2967 O  O     . LEU A 366 ? 0.48290 0.41710 0.43602 -0.03591 -0.20317 0.08872  363 LEU A O     
2968 C  CB    . LEU A 366 ? 0.39632 0.39334 0.43989 -0.02449 -0.19388 0.09914  363 LEU A CB    
2969 C  CG    . LEU A 366 ? 0.44081 0.43446 0.47705 -0.02960 -0.19196 0.09206  363 LEU A CG    
2970 C  CD1   . LEU A 366 ? 0.36277 0.38005 0.43177 -0.02694 -0.18575 0.09346  363 LEU A CD1   
2971 C  CD2   . LEU A 366 ? 0.49048 0.46870 0.50486 -0.04107 -0.20276 0.09133  363 LEU A CD2   
2972 N  N     . ASP A 367 ? 0.50442 0.45985 0.49037 -0.03926 -0.21614 0.10257  364 ASP A N     
2973 C  CA    . ASP A 367 ? 0.56130 0.49451 0.51669 -0.04932 -0.22594 0.10097  364 ASP A CA    
2974 C  C     . ASP A 367 ? 0.52049 0.42901 0.44102 -0.04815 -0.22505 0.09798  364 ASP A C     
2975 O  O     . ASP A 367 ? 0.50166 0.38666 0.38901 -0.05305 -0.22551 0.09174  364 ASP A O     
2976 C  CB    . ASP A 367 ? 0.66705 0.60820 0.63599 -0.05597 -0.23833 0.10971  364 ASP A CB    
2977 C  CG    . ASP A 367 ? 0.75674 0.72108 0.75830 -0.05790 -0.23869 0.11333  364 ASP A CG    
2978 O  OD1   . ASP A 367 ? 0.70213 0.66163 0.69716 -0.06354 -0.23856 0.10858  364 ASP A OD1   
2979 O  OD2   . ASP A 367 ? 0.82863 0.81511 0.86144 -0.05371 -0.23878 0.12123  364 ASP A OD2   
2980 N  N     . GLU A 368 ? 0.49846 0.41080 0.42497 -0.04124 -0.22264 0.10238  365 GLU A N     
2981 C  CA    . GLU A 368 ? 0.60248 0.49144 0.49602 -0.04023 -0.22111 0.10042  365 GLU A CA    
2982 C  C     . GLU A 368 ? 0.53773 0.41304 0.40972 -0.03679 -0.20964 0.09184  365 GLU A C     
2983 O  O     . GLU A 368 ? 0.57218 0.42276 0.40824 -0.03993 -0.20841 0.08709  365 GLU A O     
2984 C  CB    . GLU A 368 ? 0.57752 0.47399 0.48395 -0.03329 -0.22041 0.10747  365 GLU A CB    
2985 C  CG    . GLU A 368 ? 0.72063 0.59544 0.59674 -0.03045 -0.21538 0.10559  365 GLU A CG    
2986 C  CD    . GLU A 368 ? 0.71929 0.59936 0.60655 -0.02440 -0.21579 0.11313  365 GLU A CD    
2987 O  OE1   . GLU A 368 ? 0.70119 0.60334 0.62229 -0.01994 -0.21698 0.11895  365 GLU A OE1   
2988 O  OE2   . GLU A 368 ? 0.62842 0.48971 0.48976 -0.02376 -0.21395 0.11321  365 GLU A OE2   
2989 N  N     . HIS A 369 ? 0.47041 0.36096 0.36341 -0.03017 -0.20062 0.08986  366 HIS A N     
2990 C  CA    . HIS A 369 ? 0.48906 0.36797 0.36340 -0.02698 -0.19006 0.08235  366 HIS A CA    
2991 C  C     . HIS A 369 ? 0.49739 0.36332 0.35078 -0.03348 -0.19092 0.07515  366 HIS A C     
2992 O  O     . HIS A 369 ? 0.47323 0.31832 0.29535 -0.03328 -0.18386 0.06895  366 HIS A O     
2993 C  CB    . HIS A 369 ? 0.46670 0.36696 0.37280 -0.01904 -0.17664 0.07974  366 HIS A CB    
2994 C  CG    . HIS A 369 ? 0.44184 0.35114 0.36552 -0.01188 -0.17292 0.08525  366 HIS A CG    
2995 N  ND1   . HIS A 369 ? 0.48899 0.38309 0.39316 -0.01000 -0.17078 0.08712  366 HIS A ND1   
2996 C  CD2   . HIS A 369 ? 0.43222 0.36254 0.38977 -0.00579 -0.17014 0.08921  366 HIS A CD2   
2997 C  CE1   . HIS A 369 ? 0.47775 0.38272 0.40317 -0.00345 -0.16778 0.09208  366 HIS A CE1   
2998 N  NE2   . HIS A 369 ? 0.47376 0.40021 0.43120 -0.00042 -0.16710 0.09328  366 HIS A NE2   
2999 N  N     . SER A 370 ? 0.44925 0.32699 0.32003 -0.03882 -0.19744 0.07571  367 SER A N     
3000 C  CA    . SER A 370 ? 0.54113 0.40406 0.39109 -0.04558 -0.19904 0.06934  367 SER A CA    
3001 C  C     . SER A 370 ? 0.53724 0.37146 0.34896 -0.05128 -0.20369 0.06773  367 SER A C     
3002 O  O     . SER A 370 ? 0.57144 0.38401 0.35298 -0.05280 -0.19892 0.06057  367 SER A O     
3003 C  CB    . SER A 370 ? 0.49560 0.37504 0.37095 -0.05146 -0.20638 0.07208  367 SER A CB    
3004 O  OG    . SER A 370 ? 0.62612 0.53032 0.53449 -0.04621 -0.20039 0.07252  367 SER A OG    
3005 N  N     . GLN A 371 ? 0.54021 0.37327 0.35246 -0.05405 -0.21247 0.07433  368 GLN A N     
3006 C  CA    . GLN A 371 ? 0.58794 0.39314 0.36385 -0.05947 -0.21722 0.07313  368 GLN A CA    
3007 C  C     . GLN A 371 ? 0.62531 0.41034 0.37002 -0.05381 -0.20569 0.06825  368 GLN A C     
3008 O  O     . GLN A 371 ? 0.61600 0.37528 0.32614 -0.05614 -0.20214 0.06231  368 GLN A O     
3009 C  CB    . GLN A 371 ? 0.66897 0.47902 0.45417 -0.06307 -0.22916 0.08192  368 GLN A CB    
3010 C  CG    . GLN A 371 ? 0.76224 0.58144 0.56444 -0.07165 -0.24172 0.08643  368 GLN A CG    
3011 C  CD    . GLN A 371 ? 0.92323 0.74256 0.72833 -0.07614 -0.25423 0.09494  368 GLN A CD    
3012 O  OE1   . GLN A 371 ? 0.96664 0.77157 0.75127 -0.07457 -0.25454 0.09596  368 GLN A OE1   
3013 N  NE2   . GLN A 371 ? 1.04549 0.88096 0.87587 -0.08192 -0.26450 0.10152  368 GLN A NE2   
3014 N  N     . ALA A 372 ? 0.57983 0.37533 0.33607 -0.04612 -0.19896 0.07116  369 ALA A N     
3015 C  CA    . ALA A 372 ? 0.55803 0.33579 0.28665 -0.04083 -0.18699 0.06784  369 ALA A CA    
3016 C  C     . ALA A 372 ? 0.60087 0.36988 0.31442 -0.03817 -0.17518 0.05945  369 ALA A C     
3017 O  O     . ALA A 372 ? 0.63030 0.37560 0.30984 -0.03768 -0.16724 0.05452  369 ALA A O     
3018 C  CB    . ALA A 372 ? 0.55992 0.35153 0.30725 -0.03349 -0.18214 0.07331  369 ALA A CB    
3019 N  N     . LEU A 373 ? 0.53281 0.32097 0.27186 -0.03593 -0.17316 0.05786  370 LEU A N     
3020 C  CA    . LEU A 373 ? 0.54650 0.33157 0.28015 -0.03300 -0.15879 0.04863  370 LEU A CA    
3021 C  C     . LEU A 373 ? 0.60346 0.36471 0.30528 -0.03928 -0.16484 0.04421  370 LEU A C     
3022 O  O     . LEU A 373 ? 0.58699 0.33146 0.26453 -0.03633 -0.15306 0.03742  370 LEU A O     
3023 C  CB    . LEU A 373 ? 0.51155 0.32518 0.28560 -0.03001 -0.15374 0.04688  370 LEU A CB    
3024 C  CG    . LEU A 373 ? 0.54829 0.38175 0.35003 -0.02246 -0.14233 0.04826  370 LEU A CG    
3025 C  CD1   . LEU A 373 ? 0.47008 0.33068 0.31098 -0.02052 -0.14125 0.04825  370 LEU A CD1   
3026 C  CD2   . LEU A 373 ? 0.51550 0.34054 0.30326 -0.01689 -0.12411 0.04231  370 LEU A CD2   
3027 N  N     . SER A 374 ? 0.58515 0.34814 0.29470 -0.04727 -0.17829 0.04682  371 SER A N     
3028 C  CA    . SER A 374 ? 0.60907 0.34953 0.29316 -0.05337 -0.18092 0.04184  371 SER A CA    
3029 C  C     . SER A 374 ? 0.73698 0.44705 0.38083 -0.05300 -0.17614 0.03934  371 SER A C     
3030 O  O     . SER A 374 ? 0.67360 0.36114 0.28961 -0.05254 -0.16890 0.03277  371 SER A O     
3031 C  CB    . SER A 374 ? 0.64293 0.39060 0.34329 -0.06279 -0.19679 0.04664  371 SER A CB    
3032 O  OG    . SER A 374 ? 0.66225 0.43645 0.39816 -0.06294 -0.19889 0.04824  371 SER A OG    
3033 N  N     . GLY A 375 ? 0.71186 0.42063 0.35240 -0.05259 -0.17926 0.04468  372 GLY A N     
3034 C  CA    . GLY A 375 ? 0.74357 0.42424 0.34661 -0.05189 -0.17391 0.04274  372 GLY A CA    
3035 C  C     . GLY A 375 ? 0.73930 0.41137 0.32502 -0.04290 -0.15468 0.03775  372 GLY A C     
3036 O  O     . GLY A 375 ? 0.71480 0.36130 0.26760 -0.04140 -0.14603 0.03315  372 GLY A O     
3037 N  N     . ARG A 376 ? 0.70184 0.39499 0.31008 -0.03659 -0.14721 0.03907  373 ARG A N     
3038 C  CA    . ARG A 376 ? 0.64354 0.33151 0.23923 -0.02827 -0.12836 0.03504  373 ARG A CA    
3039 C  C     . ARG A 376 ? 0.77923 0.45827 0.36420 -0.02683 -0.12074 0.02714  373 ARG A C     
3040 O  O     . ARG A 376 ? 0.73161 0.39256 0.29124 -0.02192 -0.10629 0.02262  373 ARG A O     
3041 C  CB    . ARG A 376 ? 0.64327 0.36023 0.27582 -0.02270 -0.12113 0.03787  373 ARG A CB    
3042 C  CG    . ARG A 376 ? 0.74406 0.46602 0.38072 -0.01450 -0.09890 0.03354  373 ARG A CG    
3043 C  CD    . ARG A 376 ? 0.89879 0.64977 0.57544 -0.01056 -0.09285 0.03649  373 ARG A CD    
3044 N  NE    . ARG A 376 ? 0.91287 0.67372 0.60078 -0.00406 -0.07372 0.03259  373 ARG A NE    
3045 C  CZ    . ARG A 376 ? 0.87809 0.66389 0.60105 -0.00103 -0.06750 0.03279  373 ARG A CZ    
3046 N  NH1   . ARG A 376 ? 0.74378 0.54651 0.49343 -0.00269 -0.07698 0.03648  373 ARG A NH1   
3047 N  NH2   . ARG A 376 ? 0.79705 0.59042 0.52800 0.00393  -0.05137 0.02958  373 ARG A NH2   
3048 N  N     . LEU A 377 ? 0.70239 0.39425 0.30755 -0.03062 -0.12946 0.02576  374 LEU A N     
3049 C  CA    . LEU A 377 ? 0.68024 0.36215 0.27500 -0.02980 -0.12341 0.01850  374 LEU A CA    
3050 C  C     . LEU A 377 ? 0.75980 0.41042 0.32040 -0.03306 -0.12365 0.01507  374 LEU A C     
3051 O  O     . LEU A 377 ? 0.74392 0.37706 0.28255 -0.02773 -0.11005 0.00949  374 LEU A O     
3052 C  CB    . LEU A 377 ? 0.64954 0.35013 0.27238 -0.03473 -0.13440 0.01858  374 LEU A CB    
3053 C  CG    . LEU A 377 ? 0.67099 0.36106 0.28428 -0.03445 -0.12916 0.01143  374 LEU A CG    
3054 C  CD1   . LEU A 377 ? 0.59071 0.28326 0.20338 -0.02410 -0.10851 0.00620  374 LEU A CD1   
3055 C  CD2   . LEU A 377 ? 0.62527 0.33372 0.26673 -0.04032 -0.14046 0.01240  374 LEU A CD2   
3056 N  N     . ARG A 378 ? 0.73869 0.38167 0.29501 -0.04148 -0.13884 0.01885  375 ARG A N     
3057 C  CA    . ARG A 378 ? 0.79210 0.40292 0.31401 -0.04530 -0.14069 0.01644  375 ARG A CA    
3058 C  C     . ARG A 378 ? 0.84677 0.43709 0.33872 -0.03766 -0.12433 0.01377  375 ARG A C     
3059 O  O     . ARG A 378 ? 0.93493 0.50002 0.39947 -0.03535 -0.11609 0.00879  375 ARG A O     
3060 C  CB    . ARG A 378 ? 0.80397 0.41206 0.32701 -0.05496 -0.15909 0.02246  375 ARG A CB    
3061 C  CG    . ARG A 378 ? 0.95078 0.53184 0.44987 -0.06315 -0.16850 0.02090  375 ARG A CG    
3062 C  CD    . ARG A 378 ? 1.07536 0.65739 0.57966 -0.07305 -0.18742 0.02799  375 ARG A CD    
3063 N  NE    . ARG A 378 ? 1.14539 0.76247 0.69179 -0.07541 -0.19701 0.03421  375 ARG A NE    
3064 C  CZ    . ARG A 378 ? 1.11083 0.74410 0.67375 -0.07527 -0.20274 0.04078  375 ARG A CZ    
3065 N  NH1   . ARG A 378 ? 1.01900 0.63693 0.55990 -0.07400 -0.20135 0.04230  375 ARG A NH1   
3066 N  NH2   . ARG A 378 ? 0.93827 0.60359 0.54094 -0.07596 -0.20945 0.04624  375 ARG A NH2   
3067 N  N     . ALA A 379 ? 0.81635 0.41705 0.31381 -0.03342 -0.11895 0.01768  376 ALA A N     
3068 C  CA    . ALA A 379 ? 0.81631 0.40057 0.28864 -0.02624 -0.10253 0.01642  376 ALA A CA    
3069 C  C     . ALA A 379 ? 0.91452 0.49919 0.38437 -0.01670 -0.08260 0.01130  376 ALA A C     
3070 O  O     . ALA A 379 ? 0.84979 0.41337 0.29394 -0.01132 -0.06899 0.00821  376 ALA A O     
3071 C  CB    . ALA A 379 ? 0.84753 0.44537 0.33020 -0.02447 -0.10169 0.02282  376 ALA A CB    
3072 N  N     . ILE A 380 ? 0.80451 0.41344 0.30169 -0.01404 -0.08024 0.01079  377 ILE A N     
3073 C  CA    . ILE A 380 ? 0.79458 0.40597 0.29226 -0.00511 -0.06197 0.00624  377 ILE A CA    
3074 C  C     . ILE A 380 ? 0.86284 0.45174 0.34055 -0.00485 -0.05957 0.00023  377 ILE A C     
3075 O  O     . ILE A 380 ? 0.90694 0.48191 0.36773 0.00303  -0.04283 -0.00279 377 ILE A O     
3076 C  CB    . ILE A 380 ? 0.68305 0.32352 0.21331 -0.00367 -0.06280 0.00680  377 ILE A CB    
3077 C  CG1   . ILE A 380 ? 0.74534 0.41041 0.30339 -0.00132 -0.05841 0.01249  377 ILE A CG1   
3078 C  CG2   . ILE A 380 ? 0.75153 0.39529 0.28642 0.00412  -0.04672 0.00131  377 ILE A CG2   
3079 C  CD1   . ILE A 380 ? 0.67294 0.37344 0.27968 -0.00183 -0.06149 0.01336  377 ILE A CD1   
3080 N  N     . LEU A 381 ? 0.82264 0.40808 0.30352 -0.01333 -0.07600 -0.00076 378 LEU A N     
3081 C  CA    . LEU A 381 ? 0.91063 0.47594 0.37548 -0.01363 -0.07472 -0.00581 378 LEU A CA    
3082 C  C     . LEU A 381 ? 1.01390 0.54450 0.44170 -0.01380 -0.07210 -0.00696 378 LEU A C     
3083 O  O     . LEU A 381 ? 1.08721 0.59711 0.49692 -0.01125 -0.06635 -0.01093 378 LEU A O     
3084 C  CB    . LEU A 381 ? 0.83410 0.40676 0.31471 -0.02361 -0.09330 -0.00530 378 LEU A CB    
3085 C  CG    . LEU A 381 ? 0.81354 0.41788 0.32929 -0.02266 -0.09455 -0.00519 378 LEU A CG    
3086 C  CD1   . LEU A 381 ? 0.86907 0.48086 0.40127 -0.03271 -0.11220 -0.00388 378 LEU A CD1   
3087 C  CD2   . LEU A 381 ? 0.82619 0.43284 0.34276 -0.01250 -0.07643 -0.01026 378 LEU A CD2   
3088 N  N     . GLN A 382 ? 0.92916 0.45200 0.34465 -0.01643 -0.07601 -0.00337 379 GLN A N     
3089 C  CA    . GLN A 382 ? 1.21478 0.70348 0.59363 -0.01715 -0.07458 -0.00424 379 GLN A CA    
3090 C  C     . GLN A 382 ? 1.17930 0.65983 0.54230 -0.00703 -0.05482 -0.00424 379 GLN A C     
3091 O  O     . GLN A 382 ? 1.40322 0.85408 0.73419 -0.00587 -0.05063 -0.00528 379 GLN A O     
3092 C  CB    . GLN A 382 ? 1.13888 0.62079 0.51190 -0.02841 -0.09455 0.00002  379 GLN A CB    
3093 C  CG    . GLN A 382 ? 1.27656 0.76398 0.66383 -0.03896 -0.11377 0.00090  379 GLN A CG    
3094 C  CD    . GLN A 382 ? 1.31217 0.79486 0.69677 -0.05018 -0.13366 0.00608  379 GLN A CD    
3095 O  OE1   . GLN A 382 ? 1.27160 0.75578 0.65272 -0.05021 -0.13500 0.00971  379 GLN A OE1   
3096 N  NE2   . GLN A 382 ? 1.38920 0.86702 0.77667 -0.05991 -0.14928 0.00711  379 GLN A NE2   
3097 N  N     . ASN A 383 ? 1.14676 0.65219 0.53115 0.00020  -0.04227 -0.00269 380 ASN A N     
3098 C  CA    . ASN A 383 ? 1.34567 0.84676 0.71953 0.01024  -0.02154 -0.00194 380 ASN A CA    
3099 C  C     . ASN A 383 ? 1.35842 0.84985 0.72481 0.01979  -0.00445 -0.00615 380 ASN A C     
3100 O  O     . ASN A 383 ? 1.29637 0.80406 0.67747 0.02908  0.01295  -0.00547 380 ASN A O     
3101 C  CB    . ASN A 383 ? 1.25774 0.78952 0.65875 0.01364  -0.01473 0.00244  380 ASN A CB    
3102 C  CG    . ASN A 383 ? 1.47374 1.00120 0.86389 0.02083  0.00269  0.00547  380 ASN A CG    
3103 O  OD1   . ASN A 383 ? 1.48206 0.98584 0.84509 0.01964  0.00242  0.00606  380 ASN A OD1   
3104 N  ND2   . ASN A 383 ? 1.40168 0.95228 0.81355 0.02794  0.01787  0.00789  380 ASN A ND2   
3105 P  P     . DT  B 16  ? 1.05221 0.89867 0.94722 0.07011  0.00789  -0.02244 10  DT  B P     
3106 O  OP1   . DT  B 16  ? 0.75828 0.61845 0.66282 0.05947  0.00161  -0.02384 10  DT  B OP1   
3107 O  OP2   . DT  B 16  ? 0.78342 0.61121 0.66059 0.07965  0.01571  -0.02365 10  DT  B OP2   
3108 O  "O5'" . DT  B 16  ? 0.89946 0.72801 0.78267 0.06614  0.00291  -0.02253 10  DT  B "O5'" 
3109 C  "C5'" . DT  B 16  ? 0.85545 0.67832 0.73753 0.07460  0.00674  -0.01972 10  DT  B "C5'" 
3110 C  "C4'" . DT  B 16  ? 0.69500 0.52300 0.58433 0.06771  0.00044  -0.01773 10  DT  B "C4'" 
3111 O  "O4'" . DT  B 16  ? 0.78081 0.62867 0.68867 0.07388  0.00299  -0.01338 10  DT  B "O4'" 
3112 C  "C3'" . DT  B 16  ? 0.63564 0.47725 0.53506 0.05480  -0.00681 -0.01869 10  DT  B "C3'" 
3113 O  "O3'" . DT  B 16  ? 0.56471 0.39922 0.46068 0.04735  -0.01232 -0.01757 10  DT  B "O3'" 
3114 C  "C2'" . DT  B 16  ? 0.61458 0.48554 0.53775 0.05673  -0.00510 -0.01636 10  DT  B "C2'" 
3115 C  "C1'" . DT  B 16  ? 0.60899 0.48156 0.53597 0.06681  -0.00083 -0.01266 10  DT  B "C1'" 
3116 N  N1    . DT  B 16  ? 0.64962 0.54335 0.59361 0.07345  0.00354  -0.01030 10  DT  B N1    
3117 C  C2    . DT  B 16  ? 0.59685 0.51178 0.55853 0.07113  0.00086  -0.00749 10  DT  B C2    
3118 O  O2    . DT  B 16  ? 0.61799 0.53453 0.58104 0.06491  -0.00391 -0.00692 10  DT  B O2    
3119 N  N3    . DT  B 16  ? 0.60796 0.54125 0.58471 0.07611  0.00401  -0.00503 10  DT  B N3    
3120 C  C4    . DT  B 16  ? 0.64800 0.58202 0.62534 0.08338  0.01041  -0.00469 10  DT  B C4    
3121 O  O4    . DT  B 16  ? 0.60061 0.55294 0.59358 0.08670  0.01272  -0.00158 10  DT  B O4    
3122 C  C5    . DT  B 16  ? 0.56720 0.47793 0.52440 0.08633  0.01412  -0.00796 10  DT  B C5    
3123 C  C7    . DT  B 16  ? 0.63842 0.54631 0.59222 0.09468  0.02231  -0.00778 10  DT  B C7    
3124 C  C6    . DT  B 16  ? 0.61856 0.50974 0.55950 0.08097  0.01002  -0.01082 10  DT  B C6    
3125 P  P     . DG  B 17  ? 0.52320 0.33159 0.39834 0.03874  -0.01806 -0.01969 11  DG  B P     
3126 O  OP1   . DG  B 17  ? 0.50294 0.30087 0.37306 0.03760  -0.01985 -0.01711 11  DG  B OP1   
3127 O  OP2   . DG  B 17  ? 0.54968 0.33608 0.40432 0.04305  -0.01565 -0.02307 11  DG  B OP2   
3128 O  "O5'" . DG  B 17  ? 0.41589 0.23921 0.30267 0.02612  -0.02458 -0.01979 11  DG  B "O5'" 
3129 C  "C5'" . DG  B 17  ? 0.42185 0.26625 0.32742 0.02088  -0.02643 -0.01687 11  DG  B "C5'" 
3130 C  "C4'" . DG  B 17  ? 0.43054 0.27969 0.34104 0.00848  -0.03289 -0.01623 11  DG  B "C4'" 
3131 O  "O4'" . DG  B 17  ? 0.38348 0.24456 0.30144 0.00755  -0.03319 -0.01801 11  DG  B "O4'" 
3132 C  "C3'" . DG  B 17  ? 0.39532 0.22017 0.28772 0.00066  -0.03908 -0.01650 11  DG  B "C3'" 
3133 O  "O3'" . DG  B 17  ? 0.42045 0.25359 0.32271 -0.01069 -0.04449 -0.01312 11  DG  B "O3'" 
3134 C  "C2'" . DG  B 17  ? 0.38580 0.20230 0.26821 0.00065  -0.04067 -0.01987 11  DG  B "C2'" 
3135 C  "C1'" . DG  B 17  ? 0.41760 0.26202 0.32134 0.00168  -0.03850 -0.01962 11  DG  B "C1'" 
3136 N  N9    . DG  B 17  ? 0.42696 0.27095 0.32637 0.00796  -0.03518 -0.02260 11  DG  B N9    
3137 C  C8    . DG  B 17  ? 0.44795 0.28559 0.33978 0.01929  -0.02801 -0.02440 11  DG  B C8    
3138 N  N7    . DG  B 17  ? 0.45884 0.29934 0.34946 0.02250  -0.02566 -0.02629 11  DG  B N7    
3139 C  C5    . DG  B 17  ? 0.40802 0.25721 0.30585 0.01286  -0.03224 -0.02584 11  DG  B C5    
3140 C  C6    . DG  B 17  ? 0.52177 0.37679 0.42141 0.01120  -0.03360 -0.02688 11  DG  B C6    
3141 O  O6    . DG  B 17  ? 0.44099 0.29459 0.33566 0.01776  -0.02871 -0.02862 11  DG  B O6    
3142 N  N1    . DG  B 17  ? 0.43698 0.30102 0.34620 0.00089  -0.04123 -0.02494 11  DG  B N1    
3143 C  C2    . DG  B 17  ? 0.42082 0.28841 0.33746 -0.00693 -0.04618 -0.02208 11  DG  B C2    
3144 N  N2    . DG  B 17  ? 0.47043 0.34852 0.39803 -0.01580 -0.05269 -0.01944 11  DG  B N2    
3145 N  N3    . DG  B 17  ? 0.44850 0.31037 0.36280 -0.00594 -0.04459 -0.02120 11  DG  B N3    
3146 C  C4    . DG  B 17  ? 0.42651 0.27871 0.33076 0.00413  -0.03792 -0.02334 11  DG  B C4    
3147 P  P     . DA  B 18  ? 0.42399 0.24468 0.31996 -0.01648 -0.04723 -0.00970 12  DA  B P     
3148 O  OP1   . DA  B 18  ? 0.40951 0.19799 0.27969 -0.01617 -0.04988 -0.01178 12  DA  B OP1   
3149 O  OP2   . DA  B 18  ? 0.42198 0.25834 0.33372 -0.02773 -0.05137 -0.00551 12  DA  B OP2   
3150 O  "O5'" . DA  B 18  ? 0.39966 0.22852 0.30158 -0.00720 -0.04055 -0.00854 12  DA  B "O5'" 
3151 C  "C5'" . DA  B 18  ? 0.35237 0.20570 0.27378 -0.00828 -0.03815 -0.00585 12  DA  B "C5'" 
3152 C  "C4'" . DA  B 18  ? 0.34899 0.20991 0.27420 0.00230  -0.03251 -0.00594 12  DA  B "C4'" 
3153 O  "O4'" . DA  B 18  ? 0.33417 0.20255 0.26286 0.00999  -0.02938 -0.00911 12  DA  B "O4'" 
3154 C  "C3'" . DA  B 18  ? 0.33423 0.21537 0.27452 0.00077  -0.03045 -0.00315 12  DA  B "C3'" 
3155 O  "O3'" . DA  B 18  ? 0.35207 0.22444 0.28661 -0.00187 -0.03110 0.00038  12  DA  B "O3'" 
3156 C  "C2'" . DA  B 18  ? 0.30874 0.20148 0.25528 0.01075  -0.02636 -0.00456 12  DA  B "C2'" 
3157 C  "C1'" . DA  B 18  ? 0.29469 0.18230 0.23683 0.01522  -0.02576 -0.00820 12  DA  B "C1'" 
3158 N  N9    . DA  B 18  ? 0.33989 0.24415 0.29379 0.01451  -0.02498 -0.01017 12  DA  B N9    
3159 C  C8    . DA  B 18  ? 0.33949 0.24929 0.29613 0.02140  -0.02209 -0.01232 12  DA  B C8    
3160 N  N7    . DA  B 18  ? 0.32601 0.24944 0.29266 0.01869  -0.02224 -0.01360 12  DA  B N7    
3161 C  C5    . DA  B 18  ? 0.29110 0.21873 0.26260 0.01012  -0.02513 -0.01209 12  DA  B C5    
3162 C  C6    . DA  B 18  ? 0.25757 0.19854 0.24041 0.00463  -0.02618 -0.01185 12  DA  B C6    
3163 N  N6    . DA  B 18  ? 0.25415 0.20534 0.24407 0.00664  -0.02502 -0.01371 12  DA  B N6    
3164 N  N1    . DA  B 18  ? 0.31373 0.25714 0.30085 -0.00280 -0.02813 -0.00903 12  DA  B N1    
3165 C  C2    . DA  B 18  ? 0.28667 0.21926 0.26635 -0.00538 -0.02930 -0.00679 12  DA  B C2    
3166 N  N3    . DA  B 18  ? 0.29351 0.21159 0.26098 -0.00109 -0.02899 -0.00710 12  DA  B N3    
3167 C  C4    . DA  B 18  ? 0.34248 0.25902 0.30668 0.00709  -0.02673 -0.00980 12  DA  B C4    
3168 P  P     . DT  B 19  ? 0.38930 0.27648 0.33432 -0.00618 -0.02931 0.00422  13  DT  B P     
3169 O  OP1   . DT  B 19  ? 0.41236 0.31341 0.36967 -0.01402 -0.02976 0.00504  13  DT  B OP1   
3170 O  OP2   . DT  B 19  ? 0.42010 0.31696 0.36890 0.00194  -0.02614 0.00394  13  DT  B OP2   
3171 O  "O5'" . DT  B 19  ? 0.38618 0.25591 0.31979 -0.01099 -0.03135 0.00806  13  DT  B "O5'" 
3172 C  "C5'" . DT  B 19  ? 0.37580 0.23081 0.30203 -0.01938 -0.03587 0.00891  13  DT  B "C5'" 
3173 C  "C4'" . DT  B 19  ? 0.38663 0.23323 0.30849 -0.02683 -0.03704 0.01418  13  DT  B "C4'" 
3174 O  "O4'" . DT  B 19  ? 0.41694 0.24843 0.32584 -0.02017 -0.03599 0.01501  13  DT  B "O4'" 
3175 C  "C3'" . DT  B 19  ? 0.42252 0.28839 0.35820 -0.03136 -0.03347 0.01838  13  DT  B "C3'" 
3176 O  "O3'" . DT  B 19  ? 0.57264 0.43138 0.50657 -0.04165 -0.03553 0.02370  13  DT  B "O3'" 
3177 C  "C2'" . DT  B 19  ? 0.42261 0.28883 0.35383 -0.02286 -0.02990 0.01870  13  DT  B "C2'" 
3178 C  "C1'" . DT  B 19  ? 0.45155 0.29280 0.36546 -0.02050 -0.03288 0.01900  13  DT  B "C1'" 
3179 N  N1    . DT  B 19  ? 0.42884 0.26587 0.33638 -0.00968 -0.03114 0.01863  13  DT  B N1    
3180 C  C2    . DT  B 19  ? 0.52039 0.34380 0.41729 -0.00916 -0.03152 0.02270  13  DT  B C2    
3181 O  O2    . DT  B 19  ? 0.46617 0.28020 0.35801 -0.01751 -0.03283 0.02644  13  DT  B O2    
3182 N  N3    . DT  B 19  ? 0.45936 0.28075 0.35238 0.00136  -0.03062 0.02291  13  DT  B N3    
3183 C  C4    . DT  B 19  ? 0.41509 0.24744 0.31481 0.01074  -0.02932 0.01986  13  DT  B C4    
3184 O  O4    . DT  B 19  ? 0.44703 0.27821 0.34469 0.01954  -0.02912 0.02146  13  DT  B O4    
3185 C  C5    . DT  B 19  ? 0.44332 0.28897 0.35340 0.00922  -0.02853 0.01546  13  DT  B C5    
3186 C  C7    . DT  B 19  ? 0.44456 0.30272 0.36277 0.01808  -0.02694 0.01246  13  DT  B C7    
3187 C  C6    . DT  B 19  ? 0.39941 0.24634 0.31237 -0.00055 -0.02954 0.01493  13  DT  B C6    
3188 P  P     . DT  B 20  ? 0.80915 0.68026 0.75752 -0.05326 -0.03743 0.02744  14  DT  B P     
3189 O  OP1   . DT  B 20  ? 0.72635 0.60777 0.68322 -0.05181 -0.03915 0.02344  14  DT  B OP1   
3190 O  OP2   . DT  B 20  ? 0.78016 0.66562 0.73879 -0.05647 -0.03178 0.03298  14  DT  B OP2   
3191 O  "O5'" . DT  B 20  ? 0.74660 0.59531 0.68294 -0.06289 -0.04452 0.03017  14  DT  B "O5'" 
3192 ZN ZN    . ZN  C .   ? 0.35195 0.36185 0.37811 -0.01400 0.01656  0.01539  401 ZN  A ZN    
3193 ZN ZN    . ZN  D .   ? 0.38746 0.29830 0.27511 0.03124  0.00657  -0.00780 402 ZN  A ZN    
3194 P  P     . PO4 E .   ? 0.39434 0.31462 0.29845 0.02020  -0.01474 -0.00335 403 PO4 A P     
3195 O  O1    . PO4 E .   ? 0.36720 0.27571 0.25642 0.01727  -0.02156 -0.00038 403 PO4 A O1    
3196 O  O2    . PO4 E .   ? 0.36449 0.29878 0.28532 0.02245  -0.00637 -0.00156 403 PO4 A O2    
3197 O  O3    . PO4 E .   ? 0.36134 0.26842 0.24668 0.02366  -0.00849 -0.00596 403 PO4 A O3    
3198 O  O4    . PO4 E .   ? 0.33834 0.26794 0.25781 0.01722  -0.02292 -0.00479 403 PO4 A O4    
3199 O  O     . HOH F .   ? 0.44391 0.39398 0.42400 0.01506  -0.01996 -0.00120 501 HOH A O     
3200 O  O     . HOH F .   ? 0.54159 0.61930 0.69680 -0.07893 -0.18992 0.10254  502 HOH A O     
3201 O  O     . HOH F .   ? 0.58590 0.63879 0.69572 -0.03595 -0.08171 0.02410  503 HOH A O     
3202 O  O     . HOH F .   ? 0.52918 0.47447 0.47317 -0.01398 0.00829  0.02443  504 HOH A O     
3203 O  O     . HOH F .   ? 0.60719 0.55145 0.52383 0.00643  -0.02380 0.01364  505 HOH A O     
3204 O  O     . HOH F .   ? 0.50496 0.54328 0.56210 0.02159  -0.00370 -0.01638 506 HOH A O     
3205 O  O     . HOH F .   ? 0.39934 0.43984 0.48313 0.04813  0.05997  -0.00684 507 HOH A O     
3206 O  O     . HOH F .   ? 0.64085 0.55215 0.52681 0.02032  0.01841  0.02469  508 HOH A O     
3207 O  O     . HOH F .   ? 0.43933 0.36173 0.33988 0.04684  0.03081  -0.00978 509 HOH A O     
3208 O  O     . HOH F .   ? 0.72204 0.53029 0.44153 -0.01304 -0.00731 -0.03828 510 HOH A O     
3209 O  O     . HOH F .   ? 0.42960 0.43886 0.47605 0.03743  0.03598  -0.02453 511 HOH A O     
3210 O  O     . HOH F .   ? 0.49724 0.31260 0.26012 0.01367  -0.02975 0.00179  512 HOH A O     
3211 O  O     . HOH F .   ? 0.31033 0.33466 0.37106 -0.01358 -0.01348 0.00224  513 HOH A O     
3212 O  O     . HOH F .   ? 0.52788 0.45658 0.50503 -0.08198 -0.14637 0.01934  514 HOH A O     
3213 O  O     . HOH F .   ? 0.91587 0.58062 0.48385 0.01154  0.05930  -0.05932 515 HOH A O     
3214 O  O     . HOH F .   ? 0.63545 0.52201 0.51362 -0.00929 -0.01416 -0.04987 516 HOH A O     
3215 O  O     . HOH F .   ? 0.33470 0.34475 0.36084 -0.00909 0.01010  0.00809  517 HOH A O     
3216 O  O     . HOH F .   ? 0.68230 0.64722 0.69309 0.10235  0.15127  -0.00309 518 HOH A O     
3217 O  O     . HOH F .   ? 0.43503 0.44041 0.48724 0.01762  -0.01377 -0.00353 519 HOH A O     
3218 O  O     . HOH F .   ? 0.45953 0.43861 0.50941 0.02906  -0.03265 0.02014  520 HOH A O     
3219 O  O     . HOH F .   ? 0.62033 0.62084 0.67279 -0.03279 -0.22079 0.12119  521 HOH A O     
3220 O  O     . HOH F .   ? 0.37487 0.38413 0.41936 -0.00966 -0.05507 -0.00503 522 HOH A O     
3221 O  O     . HOH F .   ? 0.51517 0.45242 0.51894 -0.05236 -0.03902 0.01996  523 HOH A O     
3222 O  O     . HOH F .   ? 0.64586 0.52883 0.52429 0.09600  0.18138  -0.01208 524 HOH A O     
3223 O  O     . HOH F .   ? 0.43551 0.45671 0.47015 -0.01364 -0.03655 -0.02274 525 HOH A O     
3224 O  O     . HOH F .   ? 0.43458 0.47634 0.49881 -0.01513 -0.03409 -0.01530 526 HOH A O     
3225 O  O     . HOH F .   ? 0.43568 0.40725 0.42036 0.02730  -0.01072 -0.02309 527 HOH A O     
3226 O  O     . HOH F .   ? 0.58229 0.59580 0.55454 -0.05573 -0.13862 0.01925  528 HOH A O     
3227 O  O     . HOH F .   ? 0.58877 0.74487 0.80237 -0.01432 0.06469  0.07482  529 HOH A O     
3228 O  O     . HOH F .   ? 0.32951 0.28568 0.32199 0.01199  -0.09453 0.04799  530 HOH A O     
3229 O  O     . HOH F .   ? 0.57385 0.36977 0.38615 0.08662  0.13556  -0.04777 531 HOH A O     
3230 O  O     . HOH F .   ? 0.65305 0.81965 0.90730 -0.05000 -0.04134 0.07586  532 HOH A O     
3231 O  O     . HOH F .   ? 0.25566 0.23361 0.25943 0.01131  -0.05613 0.01372  533 HOH A O     
3232 O  O     . HOH F .   ? 0.54160 0.58063 0.63451 0.02363  -0.02628 0.00009  534 HOH A O     
3233 O  O     . HOH F .   ? 0.53194 0.35076 0.37307 -0.08778 -0.17089 0.01094  535 HOH A O     
3234 O  O     . HOH F .   ? 0.55000 0.37145 0.37560 0.03912  -0.00550 -0.03481 536 HOH A O     
3235 O  O     . HOH F .   ? 0.43880 0.52555 0.54034 0.04496  0.00574  0.00596  537 HOH A O     
3236 O  O     . HOH F .   ? 0.51836 0.41048 0.42735 0.03892  -0.00543 -0.02948 538 HOH A O     
3237 O  O     . HOH F .   ? 0.59946 0.61687 0.67834 -0.08866 -0.21498 0.09620  539 HOH A O     
3238 O  O     . HOH F .   ? 0.71524 0.62615 0.67680 -0.11263 -0.19648 0.04930  540 HOH A O     
3239 O  O     . HOH F .   ? 0.38891 0.40483 0.46125 0.02491  -0.03441 0.00885  541 HOH A O     
3240 O  O     . HOH F .   ? 0.48888 0.46819 0.46969 -0.02813 -0.05252 -0.02780 542 HOH A O     
3241 O  O     . HOH F .   ? 0.86133 0.60309 0.61201 0.12006  0.19962  -0.03111 543 HOH A O     
3242 O  O     . HOH F .   ? 0.76873 0.65143 0.60047 0.05115  0.06235  0.00972  544 HOH A O     
3243 O  O     . HOH F .   ? 0.28722 0.28025 0.32449 0.02001  -0.03961 0.01274  545 HOH A O     
3244 O  O     . HOH F .   ? 0.82320 0.44971 0.34469 0.04761  0.14000  -0.04424 546 HOH A O     
3245 O  O     . HOH F .   ? 0.48362 0.44927 0.42039 0.04097  0.12906  0.00807  547 HOH A O     
3246 O  O     . HOH F .   ? 0.57339 0.32713 0.36090 -0.01255 -0.06427 -0.03574 548 HOH A O     
3247 O  O     . HOH F .   ? 0.57613 0.42655 0.39880 0.09022  0.18903  -0.01321 549 HOH A O     
3248 O  O     . HOH F .   ? 0.92989 0.65166 0.60037 -0.07273 -0.22109 0.06217  550 HOH A O     
3249 O  O     . HOH F .   ? 0.63335 0.42615 0.38349 0.07941  0.16943  -0.03030 551 HOH A O     
3250 O  O     . HOH F .   ? 0.89120 0.54167 0.48697 -0.06399 -0.16653 0.01105  552 HOH A O     
3251 O  O     . HOH F .   ? 1.24401 0.74772 0.72485 0.00852  -0.04347 -0.04104 553 HOH A O     
3252 O  O     . HOH F .   ? 0.60624 0.64672 0.71287 -0.05792 -0.07729 0.02872  554 HOH A O     
3253 O  O     . HOH F .   ? 0.41863 0.35735 0.33943 0.02746  0.01286  0.00346  555 HOH A O     
3254 O  O     . HOH F .   ? 0.26198 0.25661 0.26341 0.01984  -0.02040 -0.00485 556 HOH A O     
3255 O  O     . HOH F .   ? 0.51994 0.66668 0.76339 -0.04034 -0.16276 0.12199  557 HOH A O     
3256 O  O     . HOH F .   ? 0.48739 0.49054 0.51131 0.00947  -0.00554 -0.03331 558 HOH A O     
3257 O  O     . HOH F .   ? 0.31437 0.22890 0.21642 0.01733  -0.02477 -0.01081 559 HOH A O     
3258 O  O     . HOH F .   ? 0.59732 0.47450 0.49044 -0.01232 -0.21586 0.12795  560 HOH A O     
3259 O  O     . HOH F .   ? 0.51108 0.57250 0.61385 0.01594  -0.00575 -0.00849 561 HOH A O     
3260 O  O     . HOH F .   ? 0.29443 0.25233 0.25129 0.01972  -0.01631 -0.00787 562 HOH A O     
3261 O  O     . HOH F .   ? 0.40361 0.28486 0.34037 0.03419  -0.02147 0.00028  563 HOH A O     
3262 O  O     . HOH F .   ? 0.33817 0.51669 0.58739 0.00980  0.05795  0.06940  564 HOH A O     
3263 O  O     . HOH F .   ? 0.69593 0.47685 0.45892 0.06161  0.02655  -0.03395 565 HOH A O     
3264 O  O     . HOH F .   ? 0.56750 0.58513 0.65385 -0.00508 -0.20695 0.13349  566 HOH A O     
3265 O  O     . HOH F .   ? 0.35331 0.31487 0.35537 0.00642  -0.00255 0.02309  567 HOH A O     
3266 O  O     . HOH F .   ? 0.33461 0.26979 0.30746 0.02662  -0.02018 -0.00363 568 HOH A O     
3267 O  O     . HOH F .   ? 0.36945 0.47043 0.48255 -0.01563 -0.05278 0.01125  569 HOH A O     
3268 O  O     . HOH F .   ? 0.52240 0.60014 0.61182 0.01722  0.12100  0.05155  570 HOH A O     
3269 O  O     . HOH F .   ? 0.41460 0.35778 0.36633 0.01447  -0.02435 0.01734  571 HOH A O     
3270 O  O     . HOH F .   ? 0.48997 0.45944 0.47295 0.03788  -0.00058 -0.02287 572 HOH A O     
3271 O  O     . HOH F .   ? 0.24832 0.31189 0.35595 0.07479  0.13138  0.02377  573 HOH A O     
3272 O  O     . HOH F .   ? 0.67841 0.59683 0.62679 -0.09298 -0.24464 0.09038  574 HOH A O     
3273 O  O     . HOH F .   ? 1.02455 0.76392 0.78214 0.02443  0.04320  -0.07366 575 HOH A O     
3274 O  O     . HOH F .   ? 0.81700 0.50712 0.43762 -0.00021 0.02788  -0.06883 576 HOH A O     
3275 O  O     . HOH F .   ? 0.42330 0.34601 0.36700 0.00508  -0.01930 0.01682  577 HOH A O     
3276 O  O     . HOH F .   ? 0.39679 0.43443 0.45846 0.01608  -0.00647 -0.02512 578 HOH A O     
3277 O  O     . HOH F .   ? 0.81763 0.51137 0.51297 0.07329  0.12401  -0.06315 579 HOH A O     
3278 O  O     . HOH F .   ? 0.31456 0.36996 0.38617 0.02313  -0.00475 -0.01450 580 HOH A O     
3279 O  O     . HOH F .   ? 0.42642 0.41677 0.40870 0.04123  0.03454  -0.00062 581 HOH A O     
3280 O  O     . HOH F .   ? 0.49858 0.50328 0.52279 0.01559  -0.02307 -0.01719 582 HOH A O     
3281 O  O     . HOH F .   ? 0.78497 0.50562 0.52437 0.02013  -0.03202 -0.04358 583 HOH A O     
3282 O  O     . HOH F .   ? 0.45179 0.60417 0.68674 -0.01390 -0.05103 0.05743  584 HOH A O     
3283 O  O     . HOH F .   ? 0.46310 0.57124 0.68117 0.04415  -0.07762 0.07793  585 HOH A O     
3284 O  O     . HOH F .   ? 0.61068 0.53315 0.55321 -0.06735 -0.22922 0.08924  586 HOH A O     
3285 O  O     . HOH F .   ? 0.70618 0.44147 0.34053 0.04147  0.04507  0.01326  587 HOH A O     
3286 O  O     . HOH F .   ? 0.47664 0.40462 0.40806 0.02847  0.04147  -0.04131 588 HOH A O     
3287 O  O     . HOH F .   ? 0.66623 0.39653 0.35877 0.06552  0.13246  -0.05309 589 HOH A O     
3288 O  O     . HOH F .   ? 0.35384 0.35452 0.37477 -0.00574 -0.00311 0.00136  590 HOH A O     
3289 O  O     . HOH F .   ? 0.22394 0.25728 0.27320 0.02140  -0.01186 -0.02034 591 HOH A O     
3290 O  O     . HOH F .   ? 0.84572 0.46004 0.43522 -0.03239 -0.09975 -0.03025 592 HOH A O     
3291 O  O     . HOH F .   ? 0.55174 0.52919 0.54938 0.02626  0.02646  -0.03512 593 HOH A O     
3292 O  O     . HOH F .   ? 0.58147 0.61317 0.68432 0.03335  -0.02967 0.01227  594 HOH A O     
3293 O  O     . HOH F .   ? 0.26445 0.31125 0.32825 0.02226  0.00313  -0.01038 595 HOH A O     
3294 O  O     . HOH F .   ? 0.36132 0.36507 0.38825 0.05570  -0.01958 0.00695  596 HOH A O     
3295 O  O     . HOH F .   ? 0.22932 0.21105 0.24132 0.01170  -0.02085 -0.01732 597 HOH A O     
3296 O  O     . HOH F .   ? 0.35002 0.31779 0.33386 0.01685  -0.02371 -0.02238 598 HOH A O     
3297 O  O     . HOH F .   ? 0.36755 0.43726 0.44020 -0.02908 -0.07206 0.00477  599 HOH A O     
3298 O  O     . HOH F .   ? 0.54745 0.60186 0.67846 -0.07454 -0.07987 0.04351  600 HOH A O     
3299 O  O     . HOH F .   ? 0.31588 0.31505 0.32292 0.02374  0.00177  -0.00726 601 HOH A O     
3300 O  O     . HOH F .   ? 0.34380 0.31055 0.30929 0.02223  -0.00414 -0.00307 602 HOH A O     
3301 O  O     . HOH F .   ? 0.33205 0.35328 0.36353 0.00392  0.00965  -0.00606 603 HOH A O     
3302 O  O     . HOH F .   ? 1.01155 0.57741 0.46529 0.05565  0.05284  -0.01185 604 HOH A O     
3303 O  O     . HOH F .   ? 0.70927 0.48543 0.47340 0.02558  0.05037  -0.06566 605 HOH A O     
3304 O  O     . HOH F .   ? 0.60993 0.42388 0.39646 -0.04395 -0.21625 0.09216  606 HOH A O     
3305 O  O     . HOH F .   ? 0.44488 0.53619 0.60990 -0.06577 -0.02372 0.05950  607 HOH A O     
3306 O  O     . HOH F .   ? 0.49188 0.56378 0.57844 0.06081  0.02370  0.00725  608 HOH A O     
3307 O  O     . HOH F .   ? 0.33644 0.38025 0.38351 0.04717  0.03841  0.00441  609 HOH A O     
3308 O  O     . HOH F .   ? 0.36697 0.42013 0.46013 0.05233  0.08216  0.00496  610 HOH A O     
3309 O  O     . HOH F .   ? 0.36404 0.39886 0.42919 0.00844  0.00131  -0.00295 611 HOH A O     
3310 O  O     . HOH F .   ? 0.69979 0.45771 0.49568 0.02543  -0.02634 -0.03888 612 HOH A O     
3311 O  O     . HOH F .   ? 0.28780 0.38247 0.39734 0.03247  0.00982  0.00765  613 HOH A O     
3312 O  O     . HOH F .   ? 0.55943 0.59832 0.66784 -0.01514 -0.20105 0.12422  614 HOH A O     
3313 O  O     . HOH F .   ? 0.56492 0.52064 0.55644 -0.03045 -0.22433 0.11882  615 HOH A O     
3314 O  O     . HOH F .   ? 0.41549 0.50864 0.59684 0.01275  -0.12381 0.08651  616 HOH A O     
3315 O  O     . HOH F .   ? 0.77635 0.45002 0.35293 0.07377  0.19669  -0.02385 617 HOH A O     
3316 O  O     . HOH F .   ? 0.45475 0.42866 0.43625 0.01787  -0.01760 -0.00270 618 HOH A O     
3317 O  O     . HOH F .   ? 0.54318 0.63279 0.73126 0.02663  -0.12399 0.09761  619 HOH A O     
3318 O  O     . HOH F .   ? 0.37053 0.47077 0.48924 0.01516  0.02674  0.02461  620 HOH A O     
3319 O  O     . HOH F .   ? 0.46542 0.35306 0.34603 -0.03317 -0.16642 0.05230  621 HOH A O     
3320 O  O     . HOH F .   ? 0.44642 0.48121 0.46003 -0.03484 -0.09642 0.00564  622 HOH A O     
3321 O  O     . HOH F .   ? 0.28459 0.25603 0.28202 0.01558  -0.03811 0.01272  623 HOH A O     
3322 O  O     . HOH F .   ? 0.65132 0.50303 0.41643 -0.01521 -0.02330 -0.02541 624 HOH A O     
3323 O  O     . HOH F .   ? 0.46721 0.57231 0.65053 0.02888  -0.02331 0.02849  625 HOH A O     
3324 O  O     . HOH F .   ? 0.37136 0.40767 0.42963 0.06547  0.00540  0.00148  626 HOH A O     
3325 O  O     . HOH F .   ? 0.42403 0.55282 0.62068 -0.00221 -0.01345 0.03598  627 HOH A O     
3326 O  O     . HOH F .   ? 0.47129 0.47125 0.43276 0.00390  -0.07813 0.01806  628 HOH A O     
3327 O  O     . HOH F .   ? 0.30589 0.30284 0.30145 0.04990  0.03164  -0.00787 629 HOH A O     
3328 O  O     . HOH F .   ? 0.92364 0.57081 0.48344 0.08126  0.08302  -0.01767 630 HOH A O     
3329 O  O     . HOH F .   ? 0.51515 0.41862 0.34900 0.00617  0.05612  0.00044  631 HOH A O     
3330 O  O     . HOH F .   ? 0.46125 0.45485 0.52136 0.02731  -0.07819 0.04778  632 HOH A O     
3331 O  O     . HOH F .   ? 0.47361 0.44103 0.43940 0.02962  -0.04051 0.01848  633 HOH A O     
3332 O  O     . HOH F .   ? 0.34251 0.33582 0.34946 0.01797  0.00096  0.00215  634 HOH A O     
3333 O  O     . HOH F .   ? 0.47327 0.56411 0.58705 0.07505  0.00742  0.02356  635 HOH A O     
3334 O  O     . HOH F .   ? 0.78455 0.69832 0.63564 -0.00302 0.05054  0.01770  636 HOH A O     
3335 O  O     . HOH F .   ? 0.45151 0.30420 0.27539 -0.00215 -0.08392 0.03371  637 HOH A O     
3336 O  O     . HOH F .   ? 0.44132 0.52524 0.55986 -0.02952 0.05948  0.06073  638 HOH A O     
3337 O  O     . HOH F .   ? 0.55034 0.42421 0.39638 0.01119  -0.03227 0.02511  639 HOH A O     
3338 O  O     . HOH F .   ? 0.83722 0.52900 0.57915 -0.00614 -0.05812 -0.04057 640 HOH A O     
3339 O  O     . HOH F .   ? 0.32258 0.43180 0.43488 0.01145  -0.05443 0.02103  641 HOH A O     
3340 O  O     . HOH F .   ? 0.42982 0.51614 0.56518 0.01987  0.01534  0.00665  642 HOH A O     
3341 O  O     . HOH F .   ? 0.47135 0.41755 0.45272 0.08597  0.12824  -0.01737 643 HOH A O     
3342 O  O     . HOH F .   ? 0.48083 0.54069 0.59489 -0.02203 -0.07014 0.01983  644 HOH A O     
3343 O  O     . HOH F .   ? 0.57269 0.34616 0.28065 0.03104  0.00347  -0.00903 645 HOH A O     
3344 O  O     . HOH F .   ? 0.79464 0.57550 0.64172 -0.05322 -0.09156 -0.01838 646 HOH A O     
3345 O  O     . HOH F .   ? 0.39969 0.44689 0.46701 0.01883  -0.00602 -0.01743 647 HOH A O     
3346 O  O     . HOH F .   ? 0.48426 0.43424 0.46940 -0.01343 -0.05301 -0.01570 648 HOH A O     
3347 O  O     . HOH F .   ? 1.03572 0.64464 0.71564 -0.10006 -0.14489 -0.01164 649 HOH A O     
3348 O  O     . HOH F .   ? 0.63835 0.63057 0.69898 0.01913  -0.14258 0.09181  650 HOH A O     
3349 O  O     . HOH F .   ? 0.32552 0.37021 0.40053 0.01501  -0.00987 -0.01841 651 HOH A O     
3350 O  O     . HOH F .   ? 0.40472 0.51013 0.57050 0.03355  0.03507  0.01878  652 HOH A O     
3351 O  O     . HOH F .   ? 0.69285 0.37444 0.35327 0.05252  0.10174  -0.06803 653 HOH A O     
3352 O  O     . HOH F .   ? 0.88466 0.46592 0.51011 -0.11912 -0.18259 -0.00057 654 HOH A O     
3353 O  O     . HOH F .   ? 0.34184 0.34720 0.37288 0.01689  -0.00933 -0.00369 655 HOH A O     
3354 O  O     . HOH F .   ? 1.03060 0.72651 0.66010 -0.05191 -0.05692 -0.06273 656 HOH A O     
3355 O  O     . HOH F .   ? 0.42468 0.40567 0.42875 0.04166  0.05576  -0.02749 657 HOH A O     
3356 O  O     . HOH F .   ? 0.92987 0.47511 0.42988 -0.04642 -0.12119 -0.01854 658 HOH A O     
3357 O  O     . HOH F .   ? 0.42302 0.33942 0.38506 0.02018  -0.10248 0.07241  659 HOH A O     
3358 O  O     . HOH F .   ? 0.51277 0.44823 0.42553 -0.00442 0.00114  0.01931  660 HOH A O     
3359 O  O     . HOH F .   ? 0.93977 0.51057 0.49462 -0.01092 -0.06904 -0.03941 661 HOH A O     
3360 O  O     . HOH F .   ? 0.72655 0.38051 0.32184 0.05683  0.12901  -0.05763 662 HOH A O     
3361 O  O     . HOH F .   ? 0.33533 0.42309 0.43773 0.02530  -0.00628 0.00018  663 HOH A O     
3362 O  O     . HOH F .   ? 0.46356 0.35529 0.34002 0.00652  -0.04752 -0.00772 664 HOH A O     
3363 O  O     . HOH F .   ? 0.50182 0.53516 0.49086 -0.01712 -0.12500 0.03677  665 HOH A O     
3364 O  O     . HOH F .   ? 0.35580 0.48277 0.58085 0.01263  -0.11901 0.09817  666 HOH A O     
3365 O  O     . HOH F .   ? 0.38259 0.42984 0.47562 -0.02769 -0.00889 0.02006  667 HOH A O     
3366 O  O     . HOH F .   ? 0.39450 0.36031 0.41385 0.02204  -0.08246 0.04960  668 HOH A O     
3367 O  O     . HOH F .   ? 0.48379 0.56716 0.62584 0.04106  0.03776  0.00776  669 HOH A O     
3368 O  O     . HOH F .   ? 0.63718 0.69728 0.70992 0.06506  0.17675  0.04609  670 HOH A O     
3369 O  O     . HOH F .   ? 0.32088 0.43448 0.45146 0.01717  -0.01003 0.01248  671 HOH A O     
3370 O  O     . HOH F .   ? 0.68680 0.67169 0.74409 -0.08196 -0.10225 0.02751  672 HOH A O     
3371 O  O     . HOH F .   ? 0.37079 0.32805 0.38017 0.02297  -0.06132 0.03932  673 HOH A O     
3372 O  O     . HOH F .   ? 0.45028 0.47674 0.43454 0.00133  -0.11845 0.04577  674 HOH A O     
3373 O  O     . HOH F .   ? 0.58517 0.54217 0.60123 0.01621  -0.15989 0.10390  675 HOH A O     
3374 O  O     . HOH F .   ? 0.64222 0.56417 0.61546 -0.10233 -0.17653 0.03773  676 HOH A O     
3375 O  O     . HOH F .   ? 0.64419 0.45615 0.48405 0.11317  0.17378  -0.02960 677 HOH A O     
3376 O  O     . HOH F .   ? 0.61978 0.35598 0.31104 -0.06429 -0.18520 0.03091  678 HOH A O     
3377 O  O     . HOH F .   ? 0.47514 0.51020 0.52005 -0.04023 -0.07003 -0.00690 679 HOH A O     
3378 O  O     . HOH F .   ? 0.73672 0.46994 0.53254 -0.08050 -0.12655 -0.01627 680 HOH A O     
3379 O  O     . HOH F .   ? 0.74183 0.59510 0.52996 0.06010  0.08158  0.01333  681 HOH A O     
3380 O  O     . HOH F .   ? 0.47633 0.60339 0.67940 0.01232  -0.02857 0.03701  682 HOH A O     
3381 O  O     . HOH F .   ? 0.39230 0.47024 0.51905 0.06117  0.10102  0.02062  683 HOH A O     
3382 O  O     . HOH F .   ? 0.50754 0.50986 0.55913 -0.04394 -0.01041 0.02923  684 HOH A O     
3383 O  O     . HOH F .   ? 0.53520 0.42982 0.35781 -0.00979 -0.02283 -0.01926 685 HOH A O     
3384 O  O     . HOH F .   ? 0.28483 0.33128 0.35252 0.00931  -0.01364 -0.02092 686 HOH A O     
3385 O  O     . HOH F .   ? 0.90322 0.63826 0.60177 0.10809  0.21874  -0.02091 687 HOH A O     
3386 O  O     . HOH F .   ? 0.35738 0.39671 0.42300 0.01593  -0.00850 -0.02369 688 HOH A O     
3387 O  O     . HOH F .   ? 0.51704 0.67096 0.74857 -0.01237 -0.02162 0.05337  689 HOH A O     
3388 O  O     . HOH F .   ? 0.53873 0.57363 0.60046 0.01804  -0.01191 -0.01931 690 HOH A O     
3389 O  O     . HOH F .   ? 0.43158 0.51270 0.53380 -0.02306 -0.04480 0.00313  691 HOH A O     
3390 O  O     . HOH F .   ? 0.80058 0.48127 0.42055 -0.06202 -0.17620 0.02543  692 HOH A O     
3391 O  O     . HOH F .   ? 0.54770 0.54889 0.49612 -0.01943 -0.11471 0.02488  693 HOH A O     
3392 O  O     . HOH F .   ? 0.38679 0.42488 0.45041 0.01602  -0.00480 -0.01432 694 HOH A O     
3393 O  O     . HOH F .   ? 0.62123 0.49949 0.49385 0.04645  0.01022  -0.02692 695 HOH A O     
3394 O  O     . HOH F .   ? 0.45469 0.48126 0.50960 0.01773  -0.01000 -0.01394 696 HOH A O     
3395 O  O     . HOH F .   ? 0.74080 0.48271 0.45782 -0.06636 -0.16610 0.00695  697 HOH A O     
3396 O  O     . HOH F .   ? 0.79213 0.47373 0.35644 0.05303  0.06291  0.00686  698 HOH A O     
3397 O  O     . HOH F .   ? 0.36909 0.40942 0.45445 -0.01241 -0.06005 0.00699  699 HOH A O     
3398 O  O     . HOH F .   ? 0.39362 0.46068 0.52401 0.02233  -0.03473 0.01368  700 HOH A O     
3399 O  O     . HOH F .   ? 0.54345 0.36551 0.34235 -0.02684 -0.19668 0.09588  701 HOH A O     
3400 O  O     . HOH F .   ? 0.54006 0.68951 0.79653 0.04859  -0.02206 0.06409  702 HOH A O     
3401 O  O     . HOH F .   ? 0.32633 0.31191 0.30338 0.02425  -0.04001 0.01153  703 HOH A O     
3402 O  O     . HOH F .   ? 0.85650 0.57734 0.56812 0.06769  0.02693  -0.04178 704 HOH A O     
3403 O  O     . HOH F .   ? 0.38570 0.38050 0.39981 0.01425  -0.02505 -0.01941 705 HOH A O     
3404 O  O     . HOH F .   ? 0.85538 0.57266 0.56915 0.03218  0.06135  -0.07490 706 HOH A O     
3405 O  O     . HOH F .   ? 0.66120 0.71246 0.77000 0.09149  0.13711  0.02130  707 HOH A O     
3406 O  O     . HOH F .   ? 0.67151 0.59502 0.61206 0.02049  0.02272  -0.04599 708 HOH A O     
3407 O  O     . HOH F .   ? 0.44784 0.47296 0.50588 0.00462  -0.03748 -0.00961 709 HOH A O     
3408 O  O     . HOH F .   ? 0.33339 0.29875 0.28861 0.04291  0.02670  -0.00837 710 HOH A O     
3409 O  O     . HOH F .   ? 0.79834 0.63230 0.60040 -0.03914 -0.05295 -0.05041 711 HOH A O     
3410 O  O     . HOH F .   ? 0.66530 0.62463 0.57109 -0.00740 -0.06090 0.00020  712 HOH A O     
3411 O  O     . HOH F .   ? 0.47339 0.40215 0.34614 -0.00065 -0.00324 -0.00067 713 HOH A O     
3412 O  O     . HOH F .   ? 0.47363 0.53368 0.54418 0.04909  0.02470  0.00101  714 HOH A O     
3413 O  O     . HOH F .   ? 0.70174 0.55278 0.64056 -0.06528 -0.06519 0.01281  715 HOH A O     
3414 O  O     . HOH F .   ? 0.66192 0.59817 0.66010 -0.06200 -0.08856 0.00609  716 HOH A O     
3415 O  O     . HOH F .   ? 0.60074 0.53566 0.60680 0.03215  -0.09519 0.07513  717 HOH A O     
3416 O  O     . HOH F .   ? 0.51821 0.46557 0.43562 0.05752  0.15689  0.00723  718 HOH A O     
3417 O  O     . HOH F .   ? 0.54907 0.55118 0.61488 0.02657  -0.02116 0.00364  719 HOH A O     
3418 O  O     . HOH F .   ? 0.55930 0.65280 0.70807 0.01873  0.00499  0.01043  720 HOH A O     
3419 O  O     . HOH F .   ? 0.32321 0.34319 0.37083 0.01225  -0.02863 -0.01344 721 HOH A O     
3420 O  O     . HOH F .   ? 0.51634 0.62847 0.64061 0.04067  -0.03027 0.02486  722 HOH A O     
3421 O  O     . HOH F .   ? 0.35646 0.28651 0.31857 0.04267  -0.00656 -0.02197 723 HOH A O     
3422 O  O     . HOH F .   ? 0.73905 0.63290 0.55853 -0.00363 -0.00129 -0.01310 724 HOH A O     
3423 O  O     . HOH F .   ? 0.53892 0.57028 0.58461 -0.01904 0.04734  0.03535  725 HOH A O     
3424 O  O     . HOH F .   ? 0.76126 0.53666 0.47547 -0.00726 -0.09373 0.05057  726 HOH A O     
3425 O  O     . HOH F .   ? 0.47774 0.43886 0.44822 0.04046  -0.04135 0.02377  727 HOH A O     
3426 O  O     . HOH F .   ? 0.54217 0.59069 0.69487 0.04024  -0.13457 0.11003  728 HOH A O     
3427 O  O     . HOH F .   ? 0.85638 0.65688 0.57339 0.03480  0.05063  0.02993  729 HOH A O     
3428 O  O     . HOH F .   ? 0.57480 0.59384 0.62144 0.00993  -0.02920 -0.01510 730 HOH A O     
3429 O  O     . HOH F .   ? 0.52190 0.58560 0.61157 -0.01902 -0.03451 -0.00479 731 HOH A O     
3430 O  O     . HOH F .   ? 0.39971 0.43666 0.44877 0.05335  0.01954  -0.00648 732 HOH A O     
3431 O  O     . HOH F .   ? 0.56247 0.57587 0.66544 0.03463  -0.12610 0.09362  733 HOH A O     
3432 O  O     . HOH F .   ? 0.53228 0.53440 0.57414 -0.03897 0.00309  0.03183  734 HOH A O     
3433 O  O     . HOH F .   ? 0.68795 0.57359 0.56357 0.06261  0.03332  -0.02260 735 HOH A O     
3434 O  O     . HOH F .   ? 0.51686 0.42499 0.46529 0.02187  -0.02402 0.00913  736 HOH A O     
3435 O  O     . HOH F .   ? 0.41437 0.42583 0.46189 0.01643  -0.01144 -0.00581 737 HOH A O     
3436 O  O     . HOH F .   ? 0.52919 0.49930 0.48164 0.04413  0.04488  0.00418  738 HOH A O     
3437 O  O     . HOH F .   ? 0.33620 0.22333 0.21581 0.00449  -0.07635 0.03863  739 HOH A O     
3438 O  O     . HOH F .   ? 0.86618 0.56011 0.58635 -0.00721 -0.06203 -0.04266 740 HOH A O     
3439 O  O     . HOH F .   ? 0.46391 0.49431 0.52483 0.01635  -0.01996 -0.01509 741 HOH A O     
3440 O  O     . HOH F .   ? 1.00349 0.68376 0.64556 0.11315  0.22540  -0.02654 742 HOH A O     
3441 O  O     . HOH F .   ? 0.78330 0.47689 0.47943 0.09185  0.15390  -0.05414 743 HOH A O     
3442 O  O     . HOH F .   ? 0.63422 0.71097 0.79775 -0.08928 -0.07792 0.06099  744 HOH A O     
3443 O  O     . HOH F .   ? 0.67210 0.57077 0.52744 0.05485  0.06231  0.00538  745 HOH A O     
3444 O  O     . HOH F .   ? 0.58720 0.57593 0.54303 0.01372  -0.06906 0.02203  746 HOH A O     
3445 O  O     . HOH F .   ? 0.75566 0.73212 0.79178 -0.09657 -0.16666 0.04683  747 HOH A O     
3446 O  O     . HOH F .   ? 0.49868 0.56800 0.63100 -0.04276 -0.10471 0.04045  748 HOH A O     
3447 O  O     . HOH F .   ? 0.59296 0.57271 0.53743 0.02717  0.13514  0.02739  749 HOH A O     
3448 O  O     . HOH F .   ? 1.06215 0.90244 0.85323 -0.08993 -0.13363 -0.02793 750 HOH A O     
3449 O  O     . HOH F .   ? 0.72538 0.65984 0.60100 -0.00319 -0.03392 -0.00062 751 HOH A O     
3450 O  O     . HOH F .   ? 0.77397 0.49694 0.53464 0.00907  -0.04322 -0.04114 752 HOH A O     
3451 O  O     . HOH F .   ? 0.50529 0.61263 0.68724 -0.04510 -0.09709 0.05373  753 HOH A O     
3452 O  O     . HOH F .   ? 0.74348 0.64533 0.57417 -0.00047 0.02726  0.00240  754 HOH A O     
3453 O  O     . HOH F .   ? 0.56984 0.59796 0.62865 0.01807  -0.01427 -0.01496 755 HOH A O     
3454 O  O     . HOH F .   ? 0.40577 0.43816 0.47292 0.00812  -0.00433 -0.00914 756 HOH A O     
3455 O  O     . HOH F .   ? 0.46612 0.48740 0.52391 0.01678  -0.01068 -0.01118 757 HOH A O     
3456 O  O     . HOH F .   ? 0.52386 0.53749 0.62200 0.03643  -0.08381 0.06024  758 HOH A O     
3457 O  O     . HOH F .   ? 0.53754 0.47897 0.50560 0.05638  0.00609  -0.02039 759 HOH A O     
3458 O  O     . HOH F .   ? 0.55534 0.61962 0.62969 -0.04314 -0.07789 0.00558  760 HOH A O     
3459 O  O     . HOH F .   ? 0.51643 0.51256 0.48988 0.03719  0.14020  0.02487  761 HOH A O     
3460 O  O     . HOH F .   ? 0.59566 0.65498 0.67920 0.07438  0.00272  0.01497  762 HOH A O     
3461 O  O     . HOH F .   ? 0.63644 0.54124 0.56071 0.00938  -0.02367 0.02423  763 HOH A O     
3462 O  O     . HOH F .   ? 0.62460 0.55831 0.52833 0.04515  0.04782  0.00541  764 HOH A O     
3463 O  O     . HOH F .   ? 0.56874 0.37048 0.44727 -0.03895 -0.06818 -0.01279 765 HOH A O     
3464 O  O     . HOH F .   ? 0.69451 0.63129 0.64685 0.04500  0.00304  -0.02498 766 HOH A O     
3465 O  O     . HOH F .   ? 0.49511 0.54268 0.56312 0.06218  -0.01703 0.01429  767 HOH A O     
3466 O  O     . HOH F .   ? 0.60290 0.56368 0.58409 0.04697  0.00265  -0.02181 768 HOH A O     
3467 O  O     . HOH F .   ? 0.33779 0.34870 0.36898 0.01685  0.00076  -0.00207 769 HOH A O     
3468 O  O     . HOH F .   ? 0.46849 0.47432 0.49997 0.07138  0.01147  -0.00346 770 HOH A O     
3469 O  O     . HOH F .   ? 0.68284 0.61787 0.55576 -0.00836 -0.04750 -0.00428 771 HOH A O     
3470 O  O     . HOH F .   ? 0.49835 0.45665 0.48238 0.03865  0.04677  -0.03555 772 HOH A O     
3471 O  O     . HOH F .   ? 0.67892 0.62163 0.67561 -0.05675 -0.00872 0.04325  773 HOH A O     
3472 O  O     . HOH F .   ? 0.89813 0.52727 0.45940 -0.05868 -0.16038 0.01320  774 HOH A O     
3473 O  O     . HOH F .   ? 0.92643 0.67650 0.64332 -0.08376 -0.23406 0.06354  775 HOH A O     
3474 O  O     . HOH F .   ? 0.58321 0.63803 0.65700 0.06327  -0.02729 0.02369  776 HOH A O     
3475 O  O     . HOH F .   ? 0.63840 0.69272 0.71576 0.00859  -0.01167 -0.01563 777 HOH A O     
3476 O  O     . HOH F .   ? 0.49630 0.50727 0.57825 0.03220  -0.03861 0.01951  778 HOH A O     
3477 O  O     . HOH F .   ? 0.77240 0.66218 0.71618 -0.04164 -0.01640 0.03733  779 HOH A O     
3478 O  O     . HOH F .   ? 0.65991 0.67502 0.61047 -0.03492 -0.16849 0.05512  780 HOH A O     
3479 O  O     . HOH F .   ? 0.52569 0.49586 0.48572 0.05550  0.04194  -0.00666 781 HOH A O     
3480 O  O     . HOH F .   ? 0.60428 0.61605 0.61651 0.06292  0.04530  -0.00174 782 HOH A O     
3481 O  O     . HOH F .   ? 0.76028 0.75588 0.77564 0.00157  -0.01409 -0.03384 783 HOH A O     
3482 O  O     . HOH F .   ? 0.50449 0.62990 0.69765 0.01151  -0.00338 0.03065  784 HOH A O     
3483 O  O     . HOH F .   ? 0.64458 0.75284 0.76955 -0.03583 -0.06871 0.02029  785 HOH A O     
3484 O  O     . HOH F .   ? 0.89528 0.57073 0.53215 -0.08190 -0.19560 0.02289  786 HOH A O     
3485 O  O     . HOH F .   ? 0.47847 0.47188 0.53284 0.02664  -0.04101 0.01987  787 HOH A O     
3486 O  O     . HOH F .   ? 0.53441 0.52045 0.49976 0.02143  -0.05536 0.01951  788 HOH A O     
3487 O  O     . HOH F .   ? 0.45496 0.37684 0.39567 0.03523  0.04596  -0.04327 789 HOH A O     
3488 O  O     . HOH F .   ? 0.52433 0.68848 0.77314 -0.02140 -0.04358 0.06359  790 HOH A O     
3489 O  O     . HOH F .   ? 0.49146 0.57266 0.63573 0.07442  0.10437  0.02276  791 HOH A O     
3490 O  O     . HOH F .   ? 0.56089 0.65640 0.70850 -0.04819 0.03681  0.06948  792 HOH A O     
3491 O  O     . HOH F .   ? 0.64564 0.62605 0.64568 0.01818  0.01193  -0.03671 793 HOH A O     
3492 O  O     . HOH F .   ? 0.60600 0.49515 0.53216 0.02337  -0.02809 0.02223  794 HOH A O     
3493 O  O     . HOH F .   ? 0.75760 0.48445 0.55651 -0.02973 -0.07225 -0.02757 795 HOH A O     
3494 O  O     . HOH F .   ? 1.03103 0.59971 0.52768 -0.06288 -0.16016 0.00923  796 HOH A O     
3495 O  O     . HOH F .   ? 0.56399 0.61064 0.66030 0.01857  -0.03049 0.00018  797 HOH A O     
3496 O  O     . HOH F .   ? 0.53596 0.66867 0.78011 0.03583  -0.09664 0.09893  798 HOH A O     
3497 O  O     . HOH F .   ? 0.56820 0.58611 0.53219 -0.01720 -0.13699 0.04477  799 HOH A O     
3498 O  O     . HOH F .   ? 0.64087 0.56510 0.53507 0.03641  0.03404  0.00651  800 HOH A O     
3499 O  O     . HOH F .   ? 0.64826 0.52683 0.55215 0.04200  -0.00538 -0.02977 801 HOH A O     
3500 O  O     . HOH F .   ? 0.80951 0.66520 0.67638 0.05333  0.00947  -0.03148 802 HOH A O     
3501 O  O     . HOH F .   ? 0.63772 0.60879 0.55860 -0.00303 -0.07055 0.01009  803 HOH A O     
3502 O  O     . HOH F .   ? 0.56680 0.45592 0.44459 0.00936  -0.04711 0.03226  804 HOH A O     
3503 O  O     . HOH F .   ? 0.38658 0.41072 0.43589 0.06892  -0.02140 0.01941  805 HOH A O     
3504 O  O     . HOH F .   ? 0.55241 0.45238 0.49088 0.00955  -0.02361 0.01544  806 HOH A O     
3505 O  O     . HOH F .   ? 0.86943 0.75695 0.67692 -0.00376 0.00379  -0.00566 807 HOH A O     
3506 O  O     . HOH F .   ? 0.55336 0.71130 0.79798 -0.03066 -0.07576 0.07196  808 HOH A O     
3507 O  O     . HOH F .   ? 0.57242 0.48765 0.48416 0.01300  -0.02663 0.02483  809 HOH A O     
3508 O  O     . HOH F .   ? 0.58363 0.67987 0.69657 0.05621  -0.02032 0.02430  810 HOH A O     
3509 O  O     . HOH F .   ? 0.84147 0.56034 0.54315 -0.08564 -0.19126 0.01744  811 HOH A O     
3510 O  O     . HOH F .   ? 0.51806 0.54260 0.58120 0.01380  -0.00798 -0.01349 812 HOH A O     
3511 O  O     . HOH F .   ? 0.68468 0.66596 0.65450 0.03213  -0.05820 0.02894  813 HOH A O     
3512 O  O     . HOH G .   ? 0.59877 0.51638 0.57962 -0.04287 -0.03220 0.01903  101 HOH B O     
3513 O  O     . HOH G .   ? 0.87908 0.72784 0.77122 0.09600  0.03169  -0.01987 102 HOH B O     
3514 O  O     . HOH G .   ? 0.80276 0.53232 0.60950 0.05483  -0.00950 -0.02711 103 HOH B O     
3515 O  O     . HOH G .   ? 0.44695 0.28522 0.36312 -0.04551 -0.06464 -0.00354 104 HOH B O     
3516 O  O     . HOH G .   ? 0.55092 0.30731 0.38923 -0.01540 -0.05421 -0.01909 105 HOH B O     
3517 O  O     . HOH G .   ? 0.66412 0.41710 0.50144 0.05409  -0.01292 -0.01644 106 HOH B O     
3518 O  O     . HOH G .   ? 0.52671 0.42768 0.47527 0.02010  -0.02355 0.00297  107 HOH B O     
3519 O  O     . HOH G .   ? 0.47802 0.41088 0.45018 0.00189  -0.02169 0.00203  108 HOH B O     
3520 O  O     . HOH G .   ? 0.54408 0.39126 0.47032 -0.03878 -0.05121 0.00401  109 HOH B O     
3521 O  O     . HOH G .   ? 0.73633 0.55142 0.60042 0.04389  -0.01072 -0.02948 110 HOH B O     
3522 O  O     . HOH G .   ? 0.42818 0.26632 0.33336 0.04152  -0.02665 0.01881  111 HOH B O     
3523 O  O     . HOH G .   ? 0.53056 0.35717 0.42132 -0.02548 -0.06032 -0.01798 112 HOH B O     
3524 O  O     . HOH G .   ? 0.61710 0.53242 0.59904 -0.06634 -0.01896 0.04632  113 HOH B O     
3525 O  O     . HOH G .   ? 0.71628 0.59777 0.65095 -0.03802 -0.07318 -0.01293 114 HOH B O     
3526 O  O     . HOH G .   ? 0.60868 0.34692 0.42385 0.01338  -0.03694 -0.02659 115 HOH B O     
3527 O  O     . HOH G .   ? 0.67810 0.45735 0.52246 -0.01338 -0.05557 -0.02555 116 HOH B O     
3528 O  O     . HOH G .   ? 0.63307 0.46868 0.53268 -0.04474 -0.07764 -0.01369 117 HOH B O     
3529 O  O     . HOH G .   ? 0.71605 0.47204 0.53959 0.01252  -0.03706 -0.02912 118 HOH B O     
3530 O  O     . HOH G .   ? 0.73402 0.61570 0.68019 -0.05802 -0.01799 0.04666  119 HOH B O     
3531 O  O     . HOH G .   ? 0.67886 0.51509 0.60280 -0.06842 -0.07695 0.00626  120 HOH B O     
# 
