data_8S7T
# 
_entry.id   8S7T 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8S7T         pdb_00008s7t 10.2210/pdb8s7t/pdb 
WWPDB D_1292137022 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-15 
2 'Structure model' 1 1 2025-01-22 
3 'Structure model' 1 2 2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 3 'Structure model' citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
2 2 'Structure model' '_citation.title'                   
3 3 'Structure model' '_citation.journal_volume'          
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8S7T 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-04 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              andrea.mattevi@unipv.it 
_pdbx_contact_author.name_first         Mattevi 
_pdbx_contact_author.name_last          Andrea 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-9523-7128 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Guerriere, T.B.' 1 0009-0003-3232-6822 
'Mattevi, A.'     2 0000-0002-9523-7128 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Catalysis' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2155-5435 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                1046 
_citation.page_last                 1060 
_citation.title                     
'Dehydrogenase versus oxidase function: the interplay between substrate binding and flavin microenvironment.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acscatal.4c05944 
_citation.pdbx_database_id_PubMed   39781101 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Guerriere, T.B.' 1  ? 
primary 'Vancheri, A.'    2  ? 
primary 'Ricotti, I.'     3  ? 
primary 'Serapian, S.A.'  4  ? 
primary 'Eggerichs, D.'   5  ? 
primary 'Tischler, D.'    6  ? 
primary 'Colombo, G.'     7  ? 
primary 'Mascotti, M.L.'  8  ? 
primary 'Fraaije, M.W.'   9  ? 
primary 'Mattevi, A.'     10 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Oxidoreductase                58262.785 3   ? ? ? ? 
2 non-polymer syn 'FLAVIN-ADENINE DINUCLEOTIDE' 785.550   3   ? ? ? ? 
3 non-polymer syn 'DI(HYDROXYETHYL)ETHER'       106.120   3   ? ? ? ? 
4 non-polymer syn 'CHLORIDE ION'                35.453    4   ? ? ? ? 
5 water       nat water                         18.015    292 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAAPLPEGVSAEAMSSALDRFARIVGADWVFTEDKITPYEDPYTISNDETEHRPYAAVAPASTEEVQEIVRVANEFGVPL
WPVSRGKNFAYGGAAPVMSGTVVLDMNRMNRILEVNEEFGYALVEPGVSYFELYDYIQEKGLKLWIDVPDNGWGSVVGNA
LDHGIGYTPYGDHFAMQCGMEVVLPNGEVVRTGMGAMPGNNTWQLFKYGYGPYVDGIFSQSNFGVVTKMGIWLMPEPAGY
RPYLITFENEDDIETVTERLRPLKVAGVIQNGATVRSLVLDAAITRTKSQYYDGDGPIPPSVAKTMMADLDLGMWNFCGA
LYGPPPVMDTLWTAIRDSFADIPGVKFYFPEDRRHKVDLLLHRAETMKGVPKLTEFNFLNWDGGGGHVGFSPVSPITGKD
AIKQYNMVSSRVREYGFDYMGLLAIGWRDLHHVTVIVYDKTDPDERKKLDELFNILVDEAAAEGYGEYRTHIRYMDRIAK
TYSWNDNALWKMHETIKDALDPNGILAPGKSGIWGKNRRKA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAAPLPEGVSAEAMSSALDRFARIVGADWVFTEDKITPYEDPYTISNDETEHRPYAAVAPASTEEVQEIVRVANEFGVPL
WPVSRGKNFAYGGAAPVMSGTVVLDMNRMNRILEVNEEFGYALVEPGVSYFELYDYIQEKGLKLWIDVPDNGWGSVVGNA
LDHGIGYTPYGDHFAMQCGMEVVLPNGEVVRTGMGAMPGNNTWQLFKYGYGPYVDGIFSQSNFGVVTKMGIWLMPEPAGY
RPYLITFENEDDIETVTERLRPLKVAGVIQNGATVRSLVLDAAITRTKSQYYDGDGPIPPSVAKTMMADLDLGMWNFCGA
LYGPPPVMDTLWTAIRDSFADIPGVKFYFPEDRRHKVDLLLHRAETMKGVPKLTEFNFLNWDGGGGHVGFSPVSPITGKD
AIKQYNMVSSRVREYGFDYMGLLAIGWRDLHHVTVIVYDKTDPDERKKLDELFNILVDEAAAEGYGEYRTHIRYMDRIAK
TYSWNDNALWKMHETIKDALDPNGILAPGKSGIWGKNRRKA
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'FLAVIN-ADENINE DINUCLEOTIDE' FAD 
3 'DI(HYDROXYETHYL)ETHER'       PEG 
4 'CHLORIDE ION'                CL  
5 water                         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   ALA n 
1 4   PRO n 
1 5   LEU n 
1 6   PRO n 
1 7   GLU n 
1 8   GLY n 
1 9   VAL n 
1 10  SER n 
1 11  ALA n 
1 12  GLU n 
1 13  ALA n 
1 14  MET n 
1 15  SER n 
1 16  SER n 
1 17  ALA n 
1 18  LEU n 
1 19  ASP n 
1 20  ARG n 
1 21  PHE n 
1 22  ALA n 
1 23  ARG n 
1 24  ILE n 
1 25  VAL n 
1 26  GLY n 
1 27  ALA n 
1 28  ASP n 
1 29  TRP n 
1 30  VAL n 
1 31  PHE n 
1 32  THR n 
1 33  GLU n 
1 34  ASP n 
1 35  LYS n 
1 36  ILE n 
1 37  THR n 
1 38  PRO n 
1 39  TYR n 
1 40  GLU n 
1 41  ASP n 
1 42  PRO n 
1 43  TYR n 
1 44  THR n 
1 45  ILE n 
1 46  SER n 
1 47  ASN n 
1 48  ASP n 
1 49  GLU n 
1 50  THR n 
1 51  GLU n 
1 52  HIS n 
1 53  ARG n 
1 54  PRO n 
1 55  TYR n 
1 56  ALA n 
1 57  ALA n 
1 58  VAL n 
1 59  ALA n 
1 60  PRO n 
1 61  ALA n 
1 62  SER n 
1 63  THR n 
1 64  GLU n 
1 65  GLU n 
1 66  VAL n 
1 67  GLN n 
1 68  GLU n 
1 69  ILE n 
1 70  VAL n 
1 71  ARG n 
1 72  VAL n 
1 73  ALA n 
1 74  ASN n 
1 75  GLU n 
1 76  PHE n 
1 77  GLY n 
1 78  VAL n 
1 79  PRO n 
1 80  LEU n 
1 81  TRP n 
1 82  PRO n 
1 83  VAL n 
1 84  SER n 
1 85  ARG n 
1 86  GLY n 
1 87  LYS n 
1 88  ASN n 
1 89  PHE n 
1 90  ALA n 
1 91  TYR n 
1 92  GLY n 
1 93  GLY n 
1 94  ALA n 
1 95  ALA n 
1 96  PRO n 
1 97  VAL n 
1 98  MET n 
1 99  SER n 
1 100 GLY n 
1 101 THR n 
1 102 VAL n 
1 103 VAL n 
1 104 LEU n 
1 105 ASP n 
1 106 MET n 
1 107 ASN n 
1 108 ARG n 
1 109 MET n 
1 110 ASN n 
1 111 ARG n 
1 112 ILE n 
1 113 LEU n 
1 114 GLU n 
1 115 VAL n 
1 116 ASN n 
1 117 GLU n 
1 118 GLU n 
1 119 PHE n 
1 120 GLY n 
1 121 TYR n 
1 122 ALA n 
1 123 LEU n 
1 124 VAL n 
1 125 GLU n 
1 126 PRO n 
1 127 GLY n 
1 128 VAL n 
1 129 SER n 
1 130 TYR n 
1 131 PHE n 
1 132 GLU n 
1 133 LEU n 
1 134 TYR n 
1 135 ASP n 
1 136 TYR n 
1 137 ILE n 
1 138 GLN n 
1 139 GLU n 
1 140 LYS n 
1 141 GLY n 
1 142 LEU n 
1 143 LYS n 
1 144 LEU n 
1 145 TRP n 
1 146 ILE n 
1 147 ASP n 
1 148 VAL n 
1 149 PRO n 
1 150 ASP n 
1 151 ASN n 
1 152 GLY n 
1 153 TRP n 
1 154 GLY n 
1 155 SER n 
1 156 VAL n 
1 157 VAL n 
1 158 GLY n 
1 159 ASN n 
1 160 ALA n 
1 161 LEU n 
1 162 ASP n 
1 163 HIS n 
1 164 GLY n 
1 165 ILE n 
1 166 GLY n 
1 167 TYR n 
1 168 THR n 
1 169 PRO n 
1 170 TYR n 
1 171 GLY n 
1 172 ASP n 
1 173 HIS n 
1 174 PHE n 
1 175 ALA n 
1 176 MET n 
1 177 GLN n 
1 178 CYS n 
1 179 GLY n 
1 180 MET n 
1 181 GLU n 
1 182 VAL n 
1 183 VAL n 
1 184 LEU n 
1 185 PRO n 
1 186 ASN n 
1 187 GLY n 
1 188 GLU n 
1 189 VAL n 
1 190 VAL n 
1 191 ARG n 
1 192 THR n 
1 193 GLY n 
1 194 MET n 
1 195 GLY n 
1 196 ALA n 
1 197 MET n 
1 198 PRO n 
1 199 GLY n 
1 200 ASN n 
1 201 ASN n 
1 202 THR n 
1 203 TRP n 
1 204 GLN n 
1 205 LEU n 
1 206 PHE n 
1 207 LYS n 
1 208 TYR n 
1 209 GLY n 
1 210 TYR n 
1 211 GLY n 
1 212 PRO n 
1 213 TYR n 
1 214 VAL n 
1 215 ASP n 
1 216 GLY n 
1 217 ILE n 
1 218 PHE n 
1 219 SER n 
1 220 GLN n 
1 221 SER n 
1 222 ASN n 
1 223 PHE n 
1 224 GLY n 
1 225 VAL n 
1 226 VAL n 
1 227 THR n 
1 228 LYS n 
1 229 MET n 
1 230 GLY n 
1 231 ILE n 
1 232 TRP n 
1 233 LEU n 
1 234 MET n 
1 235 PRO n 
1 236 GLU n 
1 237 PRO n 
1 238 ALA n 
1 239 GLY n 
1 240 TYR n 
1 241 ARG n 
1 242 PRO n 
1 243 TYR n 
1 244 LEU n 
1 245 ILE n 
1 246 THR n 
1 247 PHE n 
1 248 GLU n 
1 249 ASN n 
1 250 GLU n 
1 251 ASP n 
1 252 ASP n 
1 253 ILE n 
1 254 GLU n 
1 255 THR n 
1 256 VAL n 
1 257 THR n 
1 258 GLU n 
1 259 ARG n 
1 260 LEU n 
1 261 ARG n 
1 262 PRO n 
1 263 LEU n 
1 264 LYS n 
1 265 VAL n 
1 266 ALA n 
1 267 GLY n 
1 268 VAL n 
1 269 ILE n 
1 270 GLN n 
1 271 ASN n 
1 272 GLY n 
1 273 ALA n 
1 274 THR n 
1 275 VAL n 
1 276 ARG n 
1 277 SER n 
1 278 LEU n 
1 279 VAL n 
1 280 LEU n 
1 281 ASP n 
1 282 ALA n 
1 283 ALA n 
1 284 ILE n 
1 285 THR n 
1 286 ARG n 
1 287 THR n 
1 288 LYS n 
1 289 SER n 
1 290 GLN n 
1 291 TYR n 
1 292 TYR n 
1 293 ASP n 
1 294 GLY n 
1 295 ASP n 
1 296 GLY n 
1 297 PRO n 
1 298 ILE n 
1 299 PRO n 
1 300 PRO n 
1 301 SER n 
1 302 VAL n 
1 303 ALA n 
1 304 LYS n 
1 305 THR n 
1 306 MET n 
1 307 MET n 
1 308 ALA n 
1 309 ASP n 
1 310 LEU n 
1 311 ASP n 
1 312 LEU n 
1 313 GLY n 
1 314 MET n 
1 315 TRP n 
1 316 ASN n 
1 317 PHE n 
1 318 CYS n 
1 319 GLY n 
1 320 ALA n 
1 321 LEU n 
1 322 TYR n 
1 323 GLY n 
1 324 PRO n 
1 325 PRO n 
1 326 PRO n 
1 327 VAL n 
1 328 MET n 
1 329 ASP n 
1 330 THR n 
1 331 LEU n 
1 332 TRP n 
1 333 THR n 
1 334 ALA n 
1 335 ILE n 
1 336 ARG n 
1 337 ASP n 
1 338 SER n 
1 339 PHE n 
1 340 ALA n 
1 341 ASP n 
1 342 ILE n 
1 343 PRO n 
1 344 GLY n 
1 345 VAL n 
1 346 LYS n 
1 347 PHE n 
1 348 TYR n 
1 349 PHE n 
1 350 PRO n 
1 351 GLU n 
1 352 ASP n 
1 353 ARG n 
1 354 ARG n 
1 355 HIS n 
1 356 LYS n 
1 357 VAL n 
1 358 ASP n 
1 359 LEU n 
1 360 LEU n 
1 361 LEU n 
1 362 HIS n 
1 363 ARG n 
1 364 ALA n 
1 365 GLU n 
1 366 THR n 
1 367 MET n 
1 368 LYS n 
1 369 GLY n 
1 370 VAL n 
1 371 PRO n 
1 372 LYS n 
1 373 LEU n 
1 374 THR n 
1 375 GLU n 
1 376 PHE n 
1 377 ASN n 
1 378 PHE n 
1 379 LEU n 
1 380 ASN n 
1 381 TRP n 
1 382 ASP n 
1 383 GLY n 
1 384 GLY n 
1 385 GLY n 
1 386 GLY n 
1 387 HIS n 
1 388 VAL n 
1 389 GLY n 
1 390 PHE n 
1 391 SER n 
1 392 PRO n 
1 393 VAL n 
1 394 SER n 
1 395 PRO n 
1 396 ILE n 
1 397 THR n 
1 398 GLY n 
1 399 LYS n 
1 400 ASP n 
1 401 ALA n 
1 402 ILE n 
1 403 LYS n 
1 404 GLN n 
1 405 TYR n 
1 406 ASN n 
1 407 MET n 
1 408 VAL n 
1 409 SER n 
1 410 SER n 
1 411 ARG n 
1 412 VAL n 
1 413 ARG n 
1 414 GLU n 
1 415 TYR n 
1 416 GLY n 
1 417 PHE n 
1 418 ASP n 
1 419 TYR n 
1 420 MET n 
1 421 GLY n 
1 422 LEU n 
1 423 LEU n 
1 424 ALA n 
1 425 ILE n 
1 426 GLY n 
1 427 TRP n 
1 428 ARG n 
1 429 ASP n 
1 430 LEU n 
1 431 HIS n 
1 432 HIS n 
1 433 VAL n 
1 434 THR n 
1 435 VAL n 
1 436 ILE n 
1 437 VAL n 
1 438 TYR n 
1 439 ASP n 
1 440 LYS n 
1 441 THR n 
1 442 ASP n 
1 443 PRO n 
1 444 ASP n 
1 445 GLU n 
1 446 ARG n 
1 447 LYS n 
1 448 LYS n 
1 449 LEU n 
1 450 ASP n 
1 451 GLU n 
1 452 LEU n 
1 453 PHE n 
1 454 ASN n 
1 455 ILE n 
1 456 LEU n 
1 457 VAL n 
1 458 ASP n 
1 459 GLU n 
1 460 ALA n 
1 461 ALA n 
1 462 ALA n 
1 463 GLU n 
1 464 GLY n 
1 465 TYR n 
1 466 GLY n 
1 467 GLU n 
1 468 TYR n 
1 469 ARG n 
1 470 THR n 
1 471 HIS n 
1 472 ILE n 
1 473 ARG n 
1 474 TYR n 
1 475 MET n 
1 476 ASP n 
1 477 ARG n 
1 478 ILE n 
1 479 ALA n 
1 480 LYS n 
1 481 THR n 
1 482 TYR n 
1 483 SER n 
1 484 TRP n 
1 485 ASN n 
1 486 ASP n 
1 487 ASN n 
1 488 ALA n 
1 489 LEU n 
1 490 TRP n 
1 491 LYS n 
1 492 MET n 
1 493 HIS n 
1 494 GLU n 
1 495 THR n 
1 496 ILE n 
1 497 LYS n 
1 498 ASP n 
1 499 ALA n 
1 500 LEU n 
1 501 ASP n 
1 502 PRO n 
1 503 ASN n 
1 504 GLY n 
1 505 ILE n 
1 506 LEU n 
1 507 ALA n 
1 508 PRO n 
1 509 GLY n 
1 510 LYS n 
1 511 SER n 
1 512 GLY n 
1 513 ILE n 
1 514 TRP n 
1 515 GLY n 
1 516 LYS n 
1 517 ASN n 
1 518 ARG n 
1 519 ARG n 
1 520 LYS n 
1 521 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   521 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 CW354_13745 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Marinicaulis flavus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2058213 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                       ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                      ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                    ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'               ? 'C4 H7 N O4'        133.103 
CL  non-polymer         . 'CHLORIDE ION'                ? 'Cl -1'             35.453  
CYS 'L-peptide linking' y CYSTEINE                      ? 'C3 H7 N O2 S'      121.158 
FAD non-polymer         . 'FLAVIN-ADENINE DINUCLEOTIDE' ? 'C27 H33 N9 O15 P2' 785.550 
GLN 'L-peptide linking' y GLUTAMINE                     ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'               ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                       ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                     ? 'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                         ? 'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                    ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                       ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                        ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                    ? 'C5 H11 N O2 S'     149.211 
PEG non-polymer         . 'DI(HYDROXYETHYL)ETHER'       ? 'C4 H10 O3'         106.120 
PHE 'L-peptide linking' y PHENYLALANINE                 ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                       ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                        ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                     ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                    ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                      ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                        ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   3   ALA ALA A . n 
A 1 4   PRO 4   4   4   PRO PRO A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   PRO 6   6   6   PRO PRO A . n 
A 1 7   GLU 7   7   7   GLU GLU A . n 
A 1 8   GLY 8   8   8   GLY GLY A . n 
A 1 9   VAL 9   9   9   VAL VAL A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  GLU 12  12  12  GLU GLU A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  MET 14  14  14  MET MET A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  SER 16  16  16  SER SER A . n 
A 1 17  ALA 17  17  17  ALA ALA A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  ASP 19  19  19  ASP ASP A . n 
A 1 20  ARG 20  20  20  ARG ARG A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  ALA 22  22  22  ALA ALA A . n 
A 1 23  ARG 23  23  23  ARG ARG A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  ASP 28  28  28  ASP ASP A . n 
A 1 29  TRP 29  29  29  TRP TRP A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  PHE 31  31  31  PHE PHE A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  LYS 35  35  35  LYS LYS A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  THR 37  37  37  THR THR A . n 
A 1 38  PRO 38  38  38  PRO PRO A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  GLU 40  40  40  GLU GLU A . n 
A 1 41  ASP 41  41  41  ASP ASP A . n 
A 1 42  PRO 42  42  42  PRO PRO A . n 
A 1 43  TYR 43  43  43  TYR TYR A . n 
A 1 44  THR 44  44  44  THR THR A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  ASP 48  48  48  ASP ASP A . n 
A 1 49  GLU 49  49  49  GLU GLU A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  HIS 52  52  52  HIS HIS A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  VAL 58  58  58  VAL VAL A . n 
A 1 59  ALA 59  59  59  ALA ALA A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  ALA 61  61  61  ALA ALA A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  GLU 64  64  64  GLU GLU A . n 
A 1 65  GLU 65  65  65  GLU GLU A . n 
A 1 66  VAL 66  66  66  VAL VAL A . n 
A 1 67  GLN 67  67  67  GLN GLN A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  VAL 70  70  70  VAL VAL A . n 
A 1 71  ARG 71  71  71  ARG ARG A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  ALA 73  73  73  ALA ALA A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  PHE 76  76  76  PHE PHE A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  VAL 78  78  78  VAL VAL A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  TRP 81  81  81  TRP TRP A . n 
A 1 82  PRO 82  82  82  PRO PRO A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  ARG 85  85  85  ARG ARG A . n 
A 1 86  GLY 86  86  86  GLY GLY A . n 
A 1 87  LYS 87  87  87  LYS LYS A . n 
A 1 88  ASN 88  88  88  ASN ASN A . n 
A 1 89  PHE 89  89  89  PHE PHE A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  TYR 91  91  91  TYR TYR A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  ALA 94  94  94  ALA ALA A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  VAL 97  97  97  VAL VAL A . n 
A 1 98  MET 98  98  98  MET MET A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 VAL 103 103 103 VAL VAL A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 MET 106 106 106 MET MET A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 MET 109 109 109 MET MET A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 ILE 112 112 112 ILE ILE A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 GLU 114 114 114 GLU GLU A . n 
A 1 115 VAL 115 115 115 VAL VAL A . n 
A 1 116 ASN 116 116 116 ASN ASN A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 PHE 119 119 119 PHE PHE A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 TYR 121 121 121 TYR TYR A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 PRO 126 126 126 PRO PRO A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 SER 129 129 129 SER SER A . n 
A 1 130 TYR 130 130 130 TYR TYR A . n 
A 1 131 PHE 131 131 131 PHE PHE A . n 
A 1 132 GLU 132 132 132 GLU GLU A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 TYR 134 134 134 TYR TYR A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 TYR 136 136 136 TYR TYR A . n 
A 1 137 ILE 137 137 137 ILE ILE A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 GLY 141 141 141 GLY GLY A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 LYS 143 143 143 LYS LYS A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 TRP 145 145 145 TRP TRP A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 PRO 149 149 149 PRO PRO A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 ASN 151 151 151 ASN ASN A . n 
A 1 152 GLY 152 152 152 GLY GLY A . n 
A 1 153 TRP 153 153 153 TRP TRP A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 ASN 159 159 159 ASN ASN A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 ASP 162 162 162 ASP ASP A . n 
A 1 163 HIS 163 163 163 HIS HIS A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 ILE 165 165 165 ILE ILE A . n 
A 1 166 GLY 166 166 166 GLY GLY A . n 
A 1 167 TYR 167 167 167 TYR TYR A . n 
A 1 168 THR 168 168 168 THR THR A . n 
A 1 169 PRO 169 169 169 PRO PRO A . n 
A 1 170 TYR 170 170 170 TYR TYR A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 HIS 173 173 173 HIS HIS A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 CYS 178 178 178 CYS CYS A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 MET 180 180 180 MET MET A . n 
A 1 181 GLU 181 181 181 GLU GLU A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 PRO 185 185 185 PRO PRO A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 GLU 188 188 188 GLU GLU A . n 
A 1 189 VAL 189 189 189 VAL VAL A . n 
A 1 190 VAL 190 190 190 VAL VAL A . n 
A 1 191 ARG 191 191 191 ARG ARG A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 ALA 196 196 196 ALA ALA A . n 
A 1 197 MET 197 197 197 MET MET A . n 
A 1 198 PRO 198 198 198 PRO PRO A . n 
A 1 199 GLY 199 199 199 GLY GLY A . n 
A 1 200 ASN 200 200 200 ASN ASN A . n 
A 1 201 ASN 201 201 201 ASN ASN A . n 
A 1 202 THR 202 202 202 THR THR A . n 
A 1 203 TRP 203 203 203 TRP TRP A . n 
A 1 204 GLN 204 204 204 GLN GLN A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 PHE 206 206 206 PHE PHE A . n 
A 1 207 LYS 207 207 207 LYS LYS A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 TYR 210 210 210 TYR TYR A . n 
A 1 211 GLY 211 211 211 GLY GLY A . n 
A 1 212 PRO 212 212 212 PRO PRO A . n 
A 1 213 TYR 213 213 213 TYR TYR A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 ASP 215 215 215 ASP ASP A . n 
A 1 216 GLY 216 216 216 GLY GLY A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 PHE 218 218 218 PHE PHE A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 GLN 220 220 220 GLN GLN A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 ASN 222 222 222 ASN ASN A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 THR 227 227 227 THR THR A . n 
A 1 228 LYS 228 228 228 LYS LYS A . n 
A 1 229 MET 229 229 229 MET MET A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 ILE 231 231 231 ILE ILE A . n 
A 1 232 TRP 232 232 232 TRP TRP A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 MET 234 234 234 MET MET A . n 
A 1 235 PRO 235 235 235 PRO PRO A . n 
A 1 236 GLU 236 236 236 GLU GLU A . n 
A 1 237 PRO 237 237 237 PRO PRO A . n 
A 1 238 ALA 238 238 238 ALA ALA A . n 
A 1 239 GLY 239 239 239 GLY GLY A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 ARG 241 241 241 ARG ARG A . n 
A 1 242 PRO 242 242 242 PRO PRO A . n 
A 1 243 TYR 243 243 243 TYR TYR A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 THR 246 246 246 THR THR A . n 
A 1 247 PHE 247 247 247 PHE PHE A . n 
A 1 248 GLU 248 248 248 GLU GLU A . n 
A 1 249 ASN 249 249 249 ASN ASN A . n 
A 1 250 GLU 250 250 250 GLU GLU A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 ASP 252 252 252 ASP ASP A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 GLU 254 254 254 GLU GLU A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 ARG 259 259 259 ARG ARG A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 ARG 261 261 261 ARG ARG A . n 
A 1 262 PRO 262 262 262 PRO PRO A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 LYS 264 264 264 LYS LYS A . n 
A 1 265 VAL 265 265 265 VAL VAL A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 GLY 267 267 267 GLY GLY A . n 
A 1 268 VAL 268 268 268 VAL VAL A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 GLN 270 270 270 GLN GLN A . n 
A 1 271 ASN 271 271 271 ASN ASN A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 THR 274 274 274 THR THR A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 SER 277 277 277 SER SER A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 VAL 279 279 279 VAL VAL A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 ASP 281 281 281 ASP ASP A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 ILE 284 284 284 ILE ILE A . n 
A 1 285 THR 285 285 285 THR THR A . n 
A 1 286 ARG 286 286 286 ARG ARG A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 LYS 288 288 288 LYS LYS A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 GLN 290 290 290 GLN GLN A . n 
A 1 291 TYR 291 291 291 TYR TYR A . n 
A 1 292 TYR 292 292 292 TYR TYR A . n 
A 1 293 ASP 293 293 293 ASP ASP A . n 
A 1 294 GLY 294 294 294 GLY GLY A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 PRO 297 297 297 PRO PRO A . n 
A 1 298 ILE 298 298 298 ILE ILE A . n 
A 1 299 PRO 299 299 299 PRO PRO A . n 
A 1 300 PRO 300 300 300 PRO PRO A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 VAL 302 302 302 VAL VAL A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 LYS 304 304 304 LYS LYS A . n 
A 1 305 THR 305 305 305 THR THR A . n 
A 1 306 MET 306 306 306 MET MET A . n 
A 1 307 MET 307 307 307 MET MET A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 ASP 309 309 309 ASP ASP A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ASP 311 311 311 ASP ASP A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 GLY 313 313 313 GLY GLY A . n 
A 1 314 MET 314 314 314 MET MET A . n 
A 1 315 TRP 315 315 315 TRP TRP A . n 
A 1 316 ASN 316 316 316 ASN ASN A . n 
A 1 317 PHE 317 317 317 PHE PHE A . n 
A 1 318 CYS 318 318 318 CYS CYS A . n 
A 1 319 GLY 319 319 319 GLY GLY A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 TYR 322 322 322 TYR TYR A . n 
A 1 323 GLY 323 323 323 GLY GLY A . n 
A 1 324 PRO 324 324 324 PRO PRO A . n 
A 1 325 PRO 325 325 325 PRO PRO A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 VAL 327 327 327 VAL VAL A . n 
A 1 328 MET 328 328 328 MET MET A . n 
A 1 329 ASP 329 329 329 ASP ASP A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 TRP 332 332 332 TRP TRP A . n 
A 1 333 THR 333 333 333 THR THR A . n 
A 1 334 ALA 334 334 334 ALA ALA A . n 
A 1 335 ILE 335 335 335 ILE ILE A . n 
A 1 336 ARG 336 336 336 ARG ARG A . n 
A 1 337 ASP 337 337 337 ASP ASP A . n 
A 1 338 SER 338 338 338 SER SER A . n 
A 1 339 PHE 339 339 339 PHE PHE A . n 
A 1 340 ALA 340 340 340 ALA ALA A . n 
A 1 341 ASP 341 341 341 ASP ASP A . n 
A 1 342 ILE 342 342 342 ILE ILE A . n 
A 1 343 PRO 343 343 343 PRO PRO A . n 
A 1 344 GLY 344 344 344 GLY GLY A . n 
A 1 345 VAL 345 345 345 VAL VAL A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 TYR 348 348 348 TYR TYR A . n 
A 1 349 PHE 349 349 349 PHE PHE A . n 
A 1 350 PRO 350 350 350 PRO PRO A . n 
A 1 351 GLU 351 351 351 GLU GLU A . n 
A 1 352 ASP 352 352 352 ASP ASP A . n 
A 1 353 ARG 353 353 353 ARG ARG A . n 
A 1 354 ARG 354 354 354 ARG ARG A . n 
A 1 355 HIS 355 355 355 HIS HIS A . n 
A 1 356 LYS 356 356 356 LYS LYS A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 ASP 358 358 358 ASP ASP A . n 
A 1 359 LEU 359 359 359 LEU LEU A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 HIS 362 362 362 HIS HIS A . n 
A 1 363 ARG 363 363 363 ARG ARG A . n 
A 1 364 ALA 364 364 364 ALA ALA A . n 
A 1 365 GLU 365 365 365 GLU GLU A . n 
A 1 366 THR 366 366 366 THR THR A . n 
A 1 367 MET 367 367 367 MET MET A . n 
A 1 368 LYS 368 368 368 LYS LYS A . n 
A 1 369 GLY 369 369 369 GLY GLY A . n 
A 1 370 VAL 370 370 370 VAL VAL A . n 
A 1 371 PRO 371 371 371 PRO PRO A . n 
A 1 372 LYS 372 372 372 LYS LYS A . n 
A 1 373 LEU 373 373 373 LEU LEU A . n 
A 1 374 THR 374 374 374 THR THR A . n 
A 1 375 GLU 375 375 375 GLU GLU A . n 
A 1 376 PHE 376 376 376 PHE PHE A . n 
A 1 377 ASN 377 377 377 ASN ASN A . n 
A 1 378 PHE 378 378 378 PHE PHE A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 ASN 380 380 380 ASN ASN A . n 
A 1 381 TRP 381 381 381 TRP TRP A . n 
A 1 382 ASP 382 382 382 ASP ASP A . n 
A 1 383 GLY 383 383 383 GLY GLY A . n 
A 1 384 GLY 384 384 384 GLY GLY A . n 
A 1 385 GLY 385 385 385 GLY GLY A . n 
A 1 386 GLY 386 386 386 GLY GLY A . n 
A 1 387 HIS 387 387 387 HIS HIS A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 GLY 389 389 389 GLY GLY A . n 
A 1 390 PHE 390 390 390 PHE PHE A . n 
A 1 391 SER 391 391 391 SER SER A . n 
A 1 392 PRO 392 392 392 PRO PRO A . n 
A 1 393 VAL 393 393 393 VAL VAL A . n 
A 1 394 SER 394 394 394 SER SER A . n 
A 1 395 PRO 395 395 395 PRO PRO A . n 
A 1 396 ILE 396 396 396 ILE ILE A . n 
A 1 397 THR 397 397 397 THR THR A . n 
A 1 398 GLY 398 398 398 GLY GLY A . n 
A 1 399 LYS 399 399 399 LYS LYS A . n 
A 1 400 ASP 400 400 400 ASP ASP A . n 
A 1 401 ALA 401 401 401 ALA ALA A . n 
A 1 402 ILE 402 402 402 ILE ILE A . n 
A 1 403 LYS 403 403 403 LYS LYS A . n 
A 1 404 GLN 404 404 404 GLN GLN A . n 
A 1 405 TYR 405 405 405 TYR TYR A . n 
A 1 406 ASN 406 406 406 ASN ASN A . n 
A 1 407 MET 407 407 407 MET MET A . n 
A 1 408 VAL 408 408 408 VAL VAL A . n 
A 1 409 SER 409 409 409 SER SER A . n 
A 1 410 SER 410 410 410 SER SER A . n 
A 1 411 ARG 411 411 411 ARG ARG A . n 
A 1 412 VAL 412 412 412 VAL VAL A . n 
A 1 413 ARG 413 413 413 ARG ARG A . n 
A 1 414 GLU 414 414 414 GLU GLU A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 GLY 416 416 416 GLY GLY A . n 
A 1 417 PHE 417 417 417 PHE PHE A . n 
A 1 418 ASP 418 418 418 ASP ASP A . n 
A 1 419 TYR 419 419 419 TYR TYR A . n 
A 1 420 MET 420 420 420 MET MET A . n 
A 1 421 GLY 421 421 421 GLY GLY A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 LEU 423 423 423 LEU LEU A . n 
A 1 424 ALA 424 424 424 ALA ALA A . n 
A 1 425 ILE 425 425 425 ILE ILE A . n 
A 1 426 GLY 426 426 426 GLY GLY A . n 
A 1 427 TRP 427 427 427 TRP TRP A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 ASP 429 429 429 ASP ASP A . n 
A 1 430 LEU 430 430 430 LEU LEU A . n 
A 1 431 HIS 431 431 431 HIS HIS A . n 
A 1 432 HIS 432 432 432 HIS HIS A . n 
A 1 433 VAL 433 433 433 VAL VAL A . n 
A 1 434 THR 434 434 434 THR THR A . n 
A 1 435 VAL 435 435 435 VAL VAL A . n 
A 1 436 ILE 436 436 436 ILE ILE A . n 
A 1 437 VAL 437 437 437 VAL VAL A . n 
A 1 438 TYR 438 438 438 TYR TYR A . n 
A 1 439 ASP 439 439 439 ASP ASP A . n 
A 1 440 LYS 440 440 440 LYS LYS A . n 
A 1 441 THR 441 441 441 THR THR A . n 
A 1 442 ASP 442 442 442 ASP ASP A . n 
A 1 443 PRO 443 443 443 PRO PRO A . n 
A 1 444 ASP 444 444 444 ASP ASP A . n 
A 1 445 GLU 445 445 445 GLU GLU A . n 
A 1 446 ARG 446 446 446 ARG ARG A . n 
A 1 447 LYS 447 447 447 LYS LYS A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 ASP 450 450 450 ASP ASP A . n 
A 1 451 GLU 451 451 451 GLU GLU A . n 
A 1 452 LEU 452 452 452 LEU LEU A . n 
A 1 453 PHE 453 453 453 PHE PHE A . n 
A 1 454 ASN 454 454 454 ASN ASN A . n 
A 1 455 ILE 455 455 455 ILE ILE A . n 
A 1 456 LEU 456 456 456 LEU LEU A . n 
A 1 457 VAL 457 457 457 VAL VAL A . n 
A 1 458 ASP 458 458 458 ASP ASP A . n 
A 1 459 GLU 459 459 459 GLU GLU A . n 
A 1 460 ALA 460 460 460 ALA ALA A . n 
A 1 461 ALA 461 461 461 ALA ALA A . n 
A 1 462 ALA 462 462 462 ALA ALA A . n 
A 1 463 GLU 463 463 463 GLU GLU A . n 
A 1 464 GLY 464 464 464 GLY GLY A . n 
A 1 465 TYR 465 465 465 TYR TYR A . n 
A 1 466 GLY 466 466 466 GLY GLY A . n 
A 1 467 GLU 467 467 467 GLU GLU A . n 
A 1 468 TYR 468 468 468 TYR TYR A . n 
A 1 469 ARG 469 469 469 ARG ARG A . n 
A 1 470 THR 470 470 470 THR THR A . n 
A 1 471 HIS 471 471 471 HIS HIS A . n 
A 1 472 ILE 472 472 472 ILE ILE A . n 
A 1 473 ARG 473 473 473 ARG ARG A . n 
A 1 474 TYR 474 474 474 TYR TYR A . n 
A 1 475 MET 475 475 475 MET MET A . n 
A 1 476 ASP 476 476 476 ASP ASP A . n 
A 1 477 ARG 477 477 477 ARG ARG A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 ALA 479 479 479 ALA ALA A . n 
A 1 480 LYS 480 480 480 LYS LYS A . n 
A 1 481 THR 481 481 481 THR THR A . n 
A 1 482 TYR 482 482 482 TYR TYR A . n 
A 1 483 SER 483 483 483 SER SER A . n 
A 1 484 TRP 484 484 484 TRP TRP A . n 
A 1 485 ASN 485 485 485 ASN ASN A . n 
A 1 486 ASP 486 486 486 ASP ASP A . n 
A 1 487 ASN 487 487 487 ASN ASN A . n 
A 1 488 ALA 488 488 488 ALA ALA A . n 
A 1 489 LEU 489 489 489 LEU LEU A . n 
A 1 490 TRP 490 490 490 TRP TRP A . n 
A 1 491 LYS 491 491 491 LYS LYS A . n 
A 1 492 MET 492 492 492 MET MET A . n 
A 1 493 HIS 493 493 493 HIS HIS A . n 
A 1 494 GLU 494 494 494 GLU GLU A . n 
A 1 495 THR 495 495 495 THR THR A . n 
A 1 496 ILE 496 496 496 ILE ILE A . n 
A 1 497 LYS 497 497 497 LYS LYS A . n 
A 1 498 ASP 498 498 498 ASP ASP A . n 
A 1 499 ALA 499 499 499 ALA ALA A . n 
A 1 500 LEU 500 500 500 LEU LEU A . n 
A 1 501 ASP 501 501 501 ASP ASP A . n 
A 1 502 PRO 502 502 502 PRO PRO A . n 
A 1 503 ASN 503 503 503 ASN ASN A . n 
A 1 504 GLY 504 504 504 GLY GLY A . n 
A 1 505 ILE 505 505 505 ILE ILE A . n 
A 1 506 LEU 506 506 506 LEU LEU A . n 
A 1 507 ALA 507 507 507 ALA ALA A . n 
A 1 508 PRO 508 508 508 PRO PRO A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 LYS 510 510 510 LYS LYS A . n 
A 1 511 SER 511 511 511 SER SER A . n 
A 1 512 GLY 512 512 512 GLY GLY A . n 
A 1 513 ILE 513 513 513 ILE ILE A . n 
A 1 514 TRP 514 514 514 TRP TRP A . n 
A 1 515 GLY 515 515 515 GLY GLY A . n 
A 1 516 LYS 516 516 516 LYS LYS A . n 
A 1 517 ASN 517 517 517 ASN ASN A . n 
A 1 518 ARG 518 518 518 ARG ARG A . n 
A 1 519 ARG 519 519 519 ARG ARG A . n 
A 1 520 LYS 520 520 ?   ?   ?   A . n 
A 1 521 ALA 521 521 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   2   ALA ALA B . n 
B 1 3   ALA 3   3   3   ALA ALA B . n 
B 1 4   PRO 4   4   4   PRO PRO B . n 
B 1 5   LEU 5   5   5   LEU LEU B . n 
B 1 6   PRO 6   6   6   PRO PRO B . n 
B 1 7   GLU 7   7   7   GLU GLU B . n 
B 1 8   GLY 8   8   8   GLY GLY B . n 
B 1 9   VAL 9   9   9   VAL VAL B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  ALA 11  11  11  ALA ALA B . n 
B 1 12  GLU 12  12  12  GLU GLU B . n 
B 1 13  ALA 13  13  13  ALA ALA B . n 
B 1 14  MET 14  14  14  MET MET B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  SER 16  16  16  SER SER B . n 
B 1 17  ALA 17  17  17  ALA ALA B . n 
B 1 18  LEU 18  18  18  LEU LEU B . n 
B 1 19  ASP 19  19  19  ASP ASP B . n 
B 1 20  ARG 20  20  20  ARG ARG B . n 
B 1 21  PHE 21  21  21  PHE PHE B . n 
B 1 22  ALA 22  22  22  ALA ALA B . n 
B 1 23  ARG 23  23  23  ARG ARG B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  VAL 25  25  25  VAL VAL B . n 
B 1 26  GLY 26  26  26  GLY GLY B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  ASP 28  28  28  ASP ASP B . n 
B 1 29  TRP 29  29  29  TRP TRP B . n 
B 1 30  VAL 30  30  30  VAL VAL B . n 
B 1 31  PHE 31  31  31  PHE PHE B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  GLU 33  33  33  GLU GLU B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  LYS 35  35  35  LYS LYS B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  THR 37  37  37  THR THR B . n 
B 1 38  PRO 38  38  38  PRO PRO B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  GLU 40  40  40  GLU GLU B . n 
B 1 41  ASP 41  41  41  ASP ASP B . n 
B 1 42  PRO 42  42  42  PRO PRO B . n 
B 1 43  TYR 43  43  43  TYR TYR B . n 
B 1 44  THR 44  44  44  THR THR B . n 
B 1 45  ILE 45  45  45  ILE ILE B . n 
B 1 46  SER 46  46  46  SER SER B . n 
B 1 47  ASN 47  47  47  ASN ASN B . n 
B 1 48  ASP 48  48  48  ASP ASP B . n 
B 1 49  GLU 49  49  49  GLU GLU B . n 
B 1 50  THR 50  50  50  THR THR B . n 
B 1 51  GLU 51  51  51  GLU GLU B . n 
B 1 52  HIS 52  52  52  HIS HIS B . n 
B 1 53  ARG 53  53  53  ARG ARG B . n 
B 1 54  PRO 54  54  54  PRO PRO B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  ALA 56  56  56  ALA ALA B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  VAL 58  58  58  VAL VAL B . n 
B 1 59  ALA 59  59  59  ALA ALA B . n 
B 1 60  PRO 60  60  60  PRO PRO B . n 
B 1 61  ALA 61  61  61  ALA ALA B . n 
B 1 62  SER 62  62  62  SER SER B . n 
B 1 63  THR 63  63  63  THR THR B . n 
B 1 64  GLU 64  64  64  GLU GLU B . n 
B 1 65  GLU 65  65  65  GLU GLU B . n 
B 1 66  VAL 66  66  66  VAL VAL B . n 
B 1 67  GLN 67  67  67  GLN GLN B . n 
B 1 68  GLU 68  68  68  GLU GLU B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  VAL 70  70  70  VAL VAL B . n 
B 1 71  ARG 71  71  71  ARG ARG B . n 
B 1 72  VAL 72  72  72  VAL VAL B . n 
B 1 73  ALA 73  73  73  ALA ALA B . n 
B 1 74  ASN 74  74  74  ASN ASN B . n 
B 1 75  GLU 75  75  75  GLU GLU B . n 
B 1 76  PHE 76  76  76  PHE PHE B . n 
B 1 77  GLY 77  77  77  GLY GLY B . n 
B 1 78  VAL 78  78  78  VAL VAL B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  TRP 81  81  81  TRP TRP B . n 
B 1 82  PRO 82  82  82  PRO PRO B . n 
B 1 83  VAL 83  83  83  VAL VAL B . n 
B 1 84  SER 84  84  84  SER SER B . n 
B 1 85  ARG 85  85  85  ARG ARG B . n 
B 1 86  GLY 86  86  86  GLY GLY B . n 
B 1 87  LYS 87  87  87  LYS LYS B . n 
B 1 88  ASN 88  88  88  ASN ASN B . n 
B 1 89  PHE 89  89  89  PHE PHE B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  TYR 91  91  91  TYR TYR B . n 
B 1 92  GLY 92  92  92  GLY GLY B . n 
B 1 93  GLY 93  93  93  GLY GLY B . n 
B 1 94  ALA 94  94  94  ALA ALA B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  VAL 97  97  97  VAL VAL B . n 
B 1 98  MET 98  98  98  MET MET B . n 
B 1 99  SER 99  99  99  SER SER B . n 
B 1 100 GLY 100 100 100 GLY GLY B . n 
B 1 101 THR 101 101 101 THR THR B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 VAL 103 103 103 VAL VAL B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 MET 106 106 106 MET MET B . n 
B 1 107 ASN 107 107 107 ASN ASN B . n 
B 1 108 ARG 108 108 108 ARG ARG B . n 
B 1 109 MET 109 109 109 MET MET B . n 
B 1 110 ASN 110 110 110 ASN ASN B . n 
B 1 111 ARG 111 111 111 ARG ARG B . n 
B 1 112 ILE 112 112 112 ILE ILE B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 GLU 114 114 114 GLU GLU B . n 
B 1 115 VAL 115 115 115 VAL VAL B . n 
B 1 116 ASN 116 116 116 ASN ASN B . n 
B 1 117 GLU 117 117 117 GLU GLU B . n 
B 1 118 GLU 118 118 118 GLU GLU B . n 
B 1 119 PHE 119 119 119 PHE PHE B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 TYR 121 121 121 TYR TYR B . n 
B 1 122 ALA 122 122 122 ALA ALA B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 PRO 126 126 126 PRO PRO B . n 
B 1 127 GLY 127 127 127 GLY GLY B . n 
B 1 128 VAL 128 128 128 VAL VAL B . n 
B 1 129 SER 129 129 129 SER SER B . n 
B 1 130 TYR 130 130 130 TYR TYR B . n 
B 1 131 PHE 131 131 131 PHE PHE B . n 
B 1 132 GLU 132 132 132 GLU GLU B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 TYR 134 134 134 TYR TYR B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 TYR 136 136 136 TYR TYR B . n 
B 1 137 ILE 137 137 137 ILE ILE B . n 
B 1 138 GLN 138 138 138 GLN GLN B . n 
B 1 139 GLU 139 139 139 GLU GLU B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 GLY 141 141 141 GLY GLY B . n 
B 1 142 LEU 142 142 142 LEU LEU B . n 
B 1 143 LYS 143 143 143 LYS LYS B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 TRP 145 145 145 TRP TRP B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 ASP 147 147 147 ASP ASP B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 PRO 149 149 149 PRO PRO B . n 
B 1 150 ASP 150 150 150 ASP ASP B . n 
B 1 151 ASN 151 151 151 ASN ASN B . n 
B 1 152 GLY 152 152 152 GLY GLY B . n 
B 1 153 TRP 153 153 153 TRP TRP B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 SER 155 155 155 SER SER B . n 
B 1 156 VAL 156 156 156 VAL VAL B . n 
B 1 157 VAL 157 157 157 VAL VAL B . n 
B 1 158 GLY 158 158 158 GLY GLY B . n 
B 1 159 ASN 159 159 159 ASN ASN B . n 
B 1 160 ALA 160 160 160 ALA ALA B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 ASP 162 162 162 ASP ASP B . n 
B 1 163 HIS 163 163 163 HIS HIS B . n 
B 1 164 GLY 164 164 164 GLY GLY B . n 
B 1 165 ILE 165 165 165 ILE ILE B . n 
B 1 166 GLY 166 166 166 GLY GLY B . n 
B 1 167 TYR 167 167 167 TYR TYR B . n 
B 1 168 THR 168 168 168 THR THR B . n 
B 1 169 PRO 169 169 169 PRO PRO B . n 
B 1 170 TYR 170 170 170 TYR TYR B . n 
B 1 171 GLY 171 171 171 GLY GLY B . n 
B 1 172 ASP 172 172 172 ASP ASP B . n 
B 1 173 HIS 173 173 173 HIS HIS B . n 
B 1 174 PHE 174 174 174 PHE PHE B . n 
B 1 175 ALA 175 175 175 ALA ALA B . n 
B 1 176 MET 176 176 176 MET MET B . n 
B 1 177 GLN 177 177 177 GLN GLN B . n 
B 1 178 CYS 178 178 178 CYS CYS B . n 
B 1 179 GLY 179 179 179 GLY GLY B . n 
B 1 180 MET 180 180 180 MET MET B . n 
B 1 181 GLU 181 181 181 GLU GLU B . n 
B 1 182 VAL 182 182 182 VAL VAL B . n 
B 1 183 VAL 183 183 183 VAL VAL B . n 
B 1 184 LEU 184 184 184 LEU LEU B . n 
B 1 185 PRO 185 185 185 PRO PRO B . n 
B 1 186 ASN 186 186 186 ASN ASN B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 GLU 188 188 188 GLU GLU B . n 
B 1 189 VAL 189 189 189 VAL VAL B . n 
B 1 190 VAL 190 190 190 VAL VAL B . n 
B 1 191 ARG 191 191 191 ARG ARG B . n 
B 1 192 THR 192 192 192 THR THR B . n 
B 1 193 GLY 193 193 193 GLY GLY B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 ALA 196 196 196 ALA ALA B . n 
B 1 197 MET 197 197 197 MET MET B . n 
B 1 198 PRO 198 198 198 PRO PRO B . n 
B 1 199 GLY 199 199 199 GLY GLY B . n 
B 1 200 ASN 200 200 200 ASN ASN B . n 
B 1 201 ASN 201 201 201 ASN ASN B . n 
B 1 202 THR 202 202 202 THR THR B . n 
B 1 203 TRP 203 203 203 TRP TRP B . n 
B 1 204 GLN 204 204 204 GLN GLN B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 PHE 206 206 206 PHE PHE B . n 
B 1 207 LYS 207 207 207 LYS LYS B . n 
B 1 208 TYR 208 208 208 TYR TYR B . n 
B 1 209 GLY 209 209 209 GLY GLY B . n 
B 1 210 TYR 210 210 210 TYR TYR B . n 
B 1 211 GLY 211 211 211 GLY GLY B . n 
B 1 212 PRO 212 212 212 PRO PRO B . n 
B 1 213 TYR 213 213 213 TYR TYR B . n 
B 1 214 VAL 214 214 214 VAL VAL B . n 
B 1 215 ASP 215 215 215 ASP ASP B . n 
B 1 216 GLY 216 216 216 GLY GLY B . n 
B 1 217 ILE 217 217 217 ILE ILE B . n 
B 1 218 PHE 218 218 218 PHE PHE B . n 
B 1 219 SER 219 219 219 SER SER B . n 
B 1 220 GLN 220 220 220 GLN GLN B . n 
B 1 221 SER 221 221 221 SER SER B . n 
B 1 222 ASN 222 222 222 ASN ASN B . n 
B 1 223 PHE 223 223 223 PHE PHE B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 VAL 226 226 226 VAL VAL B . n 
B 1 227 THR 227 227 227 THR THR B . n 
B 1 228 LYS 228 228 228 LYS LYS B . n 
B 1 229 MET 229 229 229 MET MET B . n 
B 1 230 GLY 230 230 230 GLY GLY B . n 
B 1 231 ILE 231 231 231 ILE ILE B . n 
B 1 232 TRP 232 232 232 TRP TRP B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 MET 234 234 234 MET MET B . n 
B 1 235 PRO 235 235 235 PRO PRO B . n 
B 1 236 GLU 236 236 236 GLU GLU B . n 
B 1 237 PRO 237 237 237 PRO PRO B . n 
B 1 238 ALA 238 238 238 ALA ALA B . n 
B 1 239 GLY 239 239 239 GLY GLY B . n 
B 1 240 TYR 240 240 240 TYR TYR B . n 
B 1 241 ARG 241 241 241 ARG ARG B . n 
B 1 242 PRO 242 242 242 PRO PRO B . n 
B 1 243 TYR 243 243 243 TYR TYR B . n 
B 1 244 LEU 244 244 244 LEU LEU B . n 
B 1 245 ILE 245 245 245 ILE ILE B . n 
B 1 246 THR 246 246 246 THR THR B . n 
B 1 247 PHE 247 247 247 PHE PHE B . n 
B 1 248 GLU 248 248 248 GLU GLU B . n 
B 1 249 ASN 249 249 249 ASN ASN B . n 
B 1 250 GLU 250 250 250 GLU GLU B . n 
B 1 251 ASP 251 251 251 ASP ASP B . n 
B 1 252 ASP 252 252 252 ASP ASP B . n 
B 1 253 ILE 253 253 253 ILE ILE B . n 
B 1 254 GLU 254 254 254 GLU GLU B . n 
B 1 255 THR 255 255 255 THR THR B . n 
B 1 256 VAL 256 256 256 VAL VAL B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLU 258 258 258 GLU GLU B . n 
B 1 259 ARG 259 259 259 ARG ARG B . n 
B 1 260 LEU 260 260 260 LEU LEU B . n 
B 1 261 ARG 261 261 261 ARG ARG B . n 
B 1 262 PRO 262 262 262 PRO PRO B . n 
B 1 263 LEU 263 263 263 LEU LEU B . n 
B 1 264 LYS 264 264 264 LYS LYS B . n 
B 1 265 VAL 265 265 265 VAL VAL B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 GLY 267 267 267 GLY GLY B . n 
B 1 268 VAL 268 268 268 VAL VAL B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 GLN 270 270 270 GLN GLN B . n 
B 1 271 ASN 271 271 271 ASN ASN B . n 
B 1 272 GLY 272 272 272 GLY GLY B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 THR 274 274 274 THR THR B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 SER 277 277 277 SER SER B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 VAL 279 279 279 VAL VAL B . n 
B 1 280 LEU 280 280 280 LEU LEU B . n 
B 1 281 ASP 281 281 281 ASP ASP B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 ALA 283 283 283 ALA ALA B . n 
B 1 284 ILE 284 284 284 ILE ILE B . n 
B 1 285 THR 285 285 285 THR THR B . n 
B 1 286 ARG 286 286 286 ARG ARG B . n 
B 1 287 THR 287 287 287 THR THR B . n 
B 1 288 LYS 288 288 288 LYS LYS B . n 
B 1 289 SER 289 289 289 SER SER B . n 
B 1 290 GLN 290 290 290 GLN GLN B . n 
B 1 291 TYR 291 291 291 TYR TYR B . n 
B 1 292 TYR 292 292 292 TYR TYR B . n 
B 1 293 ASP 293 293 293 ASP ASP B . n 
B 1 294 GLY 294 294 294 GLY GLY B . n 
B 1 295 ASP 295 295 295 ASP ASP B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 PRO 297 297 297 PRO PRO B . n 
B 1 298 ILE 298 298 298 ILE ILE B . n 
B 1 299 PRO 299 299 299 PRO PRO B . n 
B 1 300 PRO 300 300 300 PRO PRO B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 VAL 302 302 302 VAL VAL B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 LYS 304 304 304 LYS LYS B . n 
B 1 305 THR 305 305 305 THR THR B . n 
B 1 306 MET 306 306 306 MET MET B . n 
B 1 307 MET 307 307 307 MET MET B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 ASP 309 309 309 ASP ASP B . n 
B 1 310 LEU 310 310 310 LEU LEU B . n 
B 1 311 ASP 311 311 311 ASP ASP B . n 
B 1 312 LEU 312 312 312 LEU LEU B . n 
B 1 313 GLY 313 313 313 GLY GLY B . n 
B 1 314 MET 314 314 314 MET MET B . n 
B 1 315 TRP 315 315 315 TRP TRP B . n 
B 1 316 ASN 316 316 316 ASN ASN B . n 
B 1 317 PHE 317 317 317 PHE PHE B . n 
B 1 318 CYS 318 318 318 CYS CYS B . n 
B 1 319 GLY 319 319 319 GLY GLY B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 LEU 321 321 321 LEU LEU B . n 
B 1 322 TYR 322 322 322 TYR TYR B . n 
B 1 323 GLY 323 323 323 GLY GLY B . n 
B 1 324 PRO 324 324 324 PRO PRO B . n 
B 1 325 PRO 325 325 325 PRO PRO B . n 
B 1 326 PRO 326 326 326 PRO PRO B . n 
B 1 327 VAL 327 327 327 VAL VAL B . n 
B 1 328 MET 328 328 328 MET MET B . n 
B 1 329 ASP 329 329 329 ASP ASP B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 LEU 331 331 331 LEU LEU B . n 
B 1 332 TRP 332 332 332 TRP TRP B . n 
B 1 333 THR 333 333 333 THR THR B . n 
B 1 334 ALA 334 334 334 ALA ALA B . n 
B 1 335 ILE 335 335 335 ILE ILE B . n 
B 1 336 ARG 336 336 336 ARG ARG B . n 
B 1 337 ASP 337 337 337 ASP ASP B . n 
B 1 338 SER 338 338 338 SER SER B . n 
B 1 339 PHE 339 339 339 PHE PHE B . n 
B 1 340 ALA 340 340 340 ALA ALA B . n 
B 1 341 ASP 341 341 341 ASP ASP B . n 
B 1 342 ILE 342 342 342 ILE ILE B . n 
B 1 343 PRO 343 343 343 PRO PRO B . n 
B 1 344 GLY 344 344 344 GLY GLY B . n 
B 1 345 VAL 345 345 345 VAL VAL B . n 
B 1 346 LYS 346 346 346 LYS LYS B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 TYR 348 348 348 TYR TYR B . n 
B 1 349 PHE 349 349 349 PHE PHE B . n 
B 1 350 PRO 350 350 350 PRO PRO B . n 
B 1 351 GLU 351 351 351 GLU GLU B . n 
B 1 352 ASP 352 352 352 ASP ASP B . n 
B 1 353 ARG 353 353 353 ARG ARG B . n 
B 1 354 ARG 354 354 354 ARG ARG B . n 
B 1 355 HIS 355 355 355 HIS HIS B . n 
B 1 356 LYS 356 356 356 LYS LYS B . n 
B 1 357 VAL 357 357 357 VAL VAL B . n 
B 1 358 ASP 358 358 358 ASP ASP B . n 
B 1 359 LEU 359 359 359 LEU LEU B . n 
B 1 360 LEU 360 360 360 LEU LEU B . n 
B 1 361 LEU 361 361 361 LEU LEU B . n 
B 1 362 HIS 362 362 362 HIS HIS B . n 
B 1 363 ARG 363 363 363 ARG ARG B . n 
B 1 364 ALA 364 364 364 ALA ALA B . n 
B 1 365 GLU 365 365 365 GLU GLU B . n 
B 1 366 THR 366 366 366 THR THR B . n 
B 1 367 MET 367 367 367 MET MET B . n 
B 1 368 LYS 368 368 368 LYS LYS B . n 
B 1 369 GLY 369 369 369 GLY GLY B . n 
B 1 370 VAL 370 370 370 VAL VAL B . n 
B 1 371 PRO 371 371 371 PRO PRO B . n 
B 1 372 LYS 372 372 372 LYS LYS B . n 
B 1 373 LEU 373 373 373 LEU LEU B . n 
B 1 374 THR 374 374 374 THR THR B . n 
B 1 375 GLU 375 375 375 GLU GLU B . n 
B 1 376 PHE 376 376 376 PHE PHE B . n 
B 1 377 ASN 377 377 377 ASN ASN B . n 
B 1 378 PHE 378 378 378 PHE PHE B . n 
B 1 379 LEU 379 379 379 LEU LEU B . n 
B 1 380 ASN 380 380 380 ASN ASN B . n 
B 1 381 TRP 381 381 381 TRP TRP B . n 
B 1 382 ASP 382 382 382 ASP ASP B . n 
B 1 383 GLY 383 383 383 GLY GLY B . n 
B 1 384 GLY 384 384 384 GLY GLY B . n 
B 1 385 GLY 385 385 385 GLY GLY B . n 
B 1 386 GLY 386 386 386 GLY GLY B . n 
B 1 387 HIS 387 387 387 HIS HIS B . n 
B 1 388 VAL 388 388 388 VAL VAL B . n 
B 1 389 GLY 389 389 389 GLY GLY B . n 
B 1 390 PHE 390 390 390 PHE PHE B . n 
B 1 391 SER 391 391 391 SER SER B . n 
B 1 392 PRO 392 392 392 PRO PRO B . n 
B 1 393 VAL 393 393 393 VAL VAL B . n 
B 1 394 SER 394 394 394 SER SER B . n 
B 1 395 PRO 395 395 395 PRO PRO B . n 
B 1 396 ILE 396 396 396 ILE ILE B . n 
B 1 397 THR 397 397 397 THR THR B . n 
B 1 398 GLY 398 398 398 GLY GLY B . n 
B 1 399 LYS 399 399 399 LYS LYS B . n 
B 1 400 ASP 400 400 400 ASP ASP B . n 
B 1 401 ALA 401 401 401 ALA ALA B . n 
B 1 402 ILE 402 402 402 ILE ILE B . n 
B 1 403 LYS 403 403 403 LYS LYS B . n 
B 1 404 GLN 404 404 404 GLN GLN B . n 
B 1 405 TYR 405 405 405 TYR TYR B . n 
B 1 406 ASN 406 406 406 ASN ASN B . n 
B 1 407 MET 407 407 407 MET MET B . n 
B 1 408 VAL 408 408 408 VAL VAL B . n 
B 1 409 SER 409 409 409 SER SER B . n 
B 1 410 SER 410 410 410 SER SER B . n 
B 1 411 ARG 411 411 411 ARG ARG B . n 
B 1 412 VAL 412 412 412 VAL VAL B . n 
B 1 413 ARG 413 413 413 ARG ARG B . n 
B 1 414 GLU 414 414 414 GLU GLU B . n 
B 1 415 TYR 415 415 415 TYR TYR B . n 
B 1 416 GLY 416 416 416 GLY GLY B . n 
B 1 417 PHE 417 417 417 PHE PHE B . n 
B 1 418 ASP 418 418 418 ASP ASP B . n 
B 1 419 TYR 419 419 419 TYR TYR B . n 
B 1 420 MET 420 420 420 MET MET B . n 
B 1 421 GLY 421 421 421 GLY GLY B . n 
B 1 422 LEU 422 422 422 LEU LEU B . n 
B 1 423 LEU 423 423 423 LEU LEU B . n 
B 1 424 ALA 424 424 424 ALA ALA B . n 
B 1 425 ILE 425 425 425 ILE ILE B . n 
B 1 426 GLY 426 426 426 GLY GLY B . n 
B 1 427 TRP 427 427 427 TRP TRP B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 ASP 429 429 429 ASP ASP B . n 
B 1 430 LEU 430 430 430 LEU LEU B . n 
B 1 431 HIS 431 431 431 HIS HIS B . n 
B 1 432 HIS 432 432 432 HIS HIS B . n 
B 1 433 VAL 433 433 433 VAL VAL B . n 
B 1 434 THR 434 434 434 THR THR B . n 
B 1 435 VAL 435 435 435 VAL VAL B . n 
B 1 436 ILE 436 436 436 ILE ILE B . n 
B 1 437 VAL 437 437 437 VAL VAL B . n 
B 1 438 TYR 438 438 438 TYR TYR B . n 
B 1 439 ASP 439 439 439 ASP ASP B . n 
B 1 440 LYS 440 440 440 LYS LYS B . n 
B 1 441 THR 441 441 441 THR THR B . n 
B 1 442 ASP 442 442 442 ASP ASP B . n 
B 1 443 PRO 443 443 443 PRO PRO B . n 
B 1 444 ASP 444 444 444 ASP ASP B . n 
B 1 445 GLU 445 445 445 GLU GLU B . n 
B 1 446 ARG 446 446 446 ARG ARG B . n 
B 1 447 LYS 447 447 447 LYS LYS B . n 
B 1 448 LYS 448 448 448 LYS LYS B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 ASP 450 450 450 ASP ASP B . n 
B 1 451 GLU 451 451 451 GLU GLU B . n 
B 1 452 LEU 452 452 452 LEU LEU B . n 
B 1 453 PHE 453 453 453 PHE PHE B . n 
B 1 454 ASN 454 454 454 ASN ASN B . n 
B 1 455 ILE 455 455 455 ILE ILE B . n 
B 1 456 LEU 456 456 456 LEU LEU B . n 
B 1 457 VAL 457 457 457 VAL VAL B . n 
B 1 458 ASP 458 458 458 ASP ASP B . n 
B 1 459 GLU 459 459 459 GLU GLU B . n 
B 1 460 ALA 460 460 460 ALA ALA B . n 
B 1 461 ALA 461 461 461 ALA ALA B . n 
B 1 462 ALA 462 462 462 ALA ALA B . n 
B 1 463 GLU 463 463 463 GLU GLU B . n 
B 1 464 GLY 464 464 464 GLY GLY B . n 
B 1 465 TYR 465 465 465 TYR TYR B . n 
B 1 466 GLY 466 466 466 GLY GLY B . n 
B 1 467 GLU 467 467 467 GLU GLU B . n 
B 1 468 TYR 468 468 468 TYR TYR B . n 
B 1 469 ARG 469 469 469 ARG ARG B . n 
B 1 470 THR 470 470 470 THR THR B . n 
B 1 471 HIS 471 471 471 HIS HIS B . n 
B 1 472 ILE 472 472 472 ILE ILE B . n 
B 1 473 ARG 473 473 473 ARG ARG B . n 
B 1 474 TYR 474 474 474 TYR TYR B . n 
B 1 475 MET 475 475 475 MET MET B . n 
B 1 476 ASP 476 476 476 ASP ASP B . n 
B 1 477 ARG 477 477 477 ARG ARG B . n 
B 1 478 ILE 478 478 478 ILE ILE B . n 
B 1 479 ALA 479 479 479 ALA ALA B . n 
B 1 480 LYS 480 480 480 LYS LYS B . n 
B 1 481 THR 481 481 481 THR THR B . n 
B 1 482 TYR 482 482 482 TYR TYR B . n 
B 1 483 SER 483 483 483 SER SER B . n 
B 1 484 TRP 484 484 484 TRP TRP B . n 
B 1 485 ASN 485 485 485 ASN ASN B . n 
B 1 486 ASP 486 486 486 ASP ASP B . n 
B 1 487 ASN 487 487 487 ASN ASN B . n 
B 1 488 ALA 488 488 488 ALA ALA B . n 
B 1 489 LEU 489 489 489 LEU LEU B . n 
B 1 490 TRP 490 490 490 TRP TRP B . n 
B 1 491 LYS 491 491 491 LYS LYS B . n 
B 1 492 MET 492 492 492 MET MET B . n 
B 1 493 HIS 493 493 493 HIS HIS B . n 
B 1 494 GLU 494 494 494 GLU GLU B . n 
B 1 495 THR 495 495 495 THR THR B . n 
B 1 496 ILE 496 496 496 ILE ILE B . n 
B 1 497 LYS 497 497 497 LYS LYS B . n 
B 1 498 ASP 498 498 498 ASP ASP B . n 
B 1 499 ALA 499 499 499 ALA ALA B . n 
B 1 500 LEU 500 500 500 LEU LEU B . n 
B 1 501 ASP 501 501 501 ASP ASP B . n 
B 1 502 PRO 502 502 502 PRO PRO B . n 
B 1 503 ASN 503 503 503 ASN ASN B . n 
B 1 504 GLY 504 504 504 GLY GLY B . n 
B 1 505 ILE 505 505 505 ILE ILE B . n 
B 1 506 LEU 506 506 506 LEU LEU B . n 
B 1 507 ALA 507 507 507 ALA ALA B . n 
B 1 508 PRO 508 508 508 PRO PRO B . n 
B 1 509 GLY 509 509 509 GLY GLY B . n 
B 1 510 LYS 510 510 510 LYS LYS B . n 
B 1 511 SER 511 511 511 SER SER B . n 
B 1 512 GLY 512 512 512 GLY GLY B . n 
B 1 513 ILE 513 513 513 ILE ILE B . n 
B 1 514 TRP 514 514 514 TRP TRP B . n 
B 1 515 GLY 515 515 515 GLY GLY B . n 
B 1 516 LYS 516 516 516 LYS LYS B . n 
B 1 517 ASN 517 517 517 ASN ASN B . n 
B 1 518 ARG 518 518 518 ARG ARG B . n 
B 1 519 ARG 519 519 519 ARG ARG B . n 
B 1 520 LYS 520 520 ?   ?   ?   B . n 
B 1 521 ALA 521 521 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   ALA 2   2   2   ALA ALA C . n 
C 1 3   ALA 3   3   3   ALA ALA C . n 
C 1 4   PRO 4   4   4   PRO PRO C . n 
C 1 5   LEU 5   5   5   LEU LEU C . n 
C 1 6   PRO 6   6   6   PRO PRO C . n 
C 1 7   GLU 7   7   7   GLU GLU C . n 
C 1 8   GLY 8   8   8   GLY GLY C . n 
C 1 9   VAL 9   9   9   VAL VAL C . n 
C 1 10  SER 10  10  10  SER SER C . n 
C 1 11  ALA 11  11  11  ALA ALA C . n 
C 1 12  GLU 12  12  12  GLU GLU C . n 
C 1 13  ALA 13  13  13  ALA ALA C . n 
C 1 14  MET 14  14  14  MET MET C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  SER 16  16  16  SER SER C . n 
C 1 17  ALA 17  17  17  ALA ALA C . n 
C 1 18  LEU 18  18  18  LEU LEU C . n 
C 1 19  ASP 19  19  19  ASP ASP C . n 
C 1 20  ARG 20  20  20  ARG ARG C . n 
C 1 21  PHE 21  21  21  PHE PHE C . n 
C 1 22  ALA 22  22  22  ALA ALA C . n 
C 1 23  ARG 23  23  23  ARG ARG C . n 
C 1 24  ILE 24  24  24  ILE ILE C . n 
C 1 25  VAL 25  25  25  VAL VAL C . n 
C 1 26  GLY 26  26  26  GLY GLY C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  ASP 28  28  28  ASP ASP C . n 
C 1 29  TRP 29  29  29  TRP TRP C . n 
C 1 30  VAL 30  30  30  VAL VAL C . n 
C 1 31  PHE 31  31  31  PHE PHE C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  GLU 33  33  33  GLU GLU C . n 
C 1 34  ASP 34  34  34  ASP ASP C . n 
C 1 35  LYS 35  35  35  LYS LYS C . n 
C 1 36  ILE 36  36  36  ILE ILE C . n 
C 1 37  THR 37  37  37  THR THR C . n 
C 1 38  PRO 38  38  38  PRO PRO C . n 
C 1 39  TYR 39  39  39  TYR TYR C . n 
C 1 40  GLU 40  40  40  GLU GLU C . n 
C 1 41  ASP 41  41  41  ASP ASP C . n 
C 1 42  PRO 42  42  42  PRO PRO C . n 
C 1 43  TYR 43  43  43  TYR TYR C . n 
C 1 44  THR 44  44  44  THR THR C . n 
C 1 45  ILE 45  45  45  ILE ILE C . n 
C 1 46  SER 46  46  46  SER SER C . n 
C 1 47  ASN 47  47  47  ASN ASN C . n 
C 1 48  ASP 48  48  48  ASP ASP C . n 
C 1 49  GLU 49  49  49  GLU GLU C . n 
C 1 50  THR 50  50  50  THR THR C . n 
C 1 51  GLU 51  51  51  GLU GLU C . n 
C 1 52  HIS 52  52  52  HIS HIS C . n 
C 1 53  ARG 53  53  53  ARG ARG C . n 
C 1 54  PRO 54  54  54  PRO PRO C . n 
C 1 55  TYR 55  55  55  TYR TYR C . n 
C 1 56  ALA 56  56  56  ALA ALA C . n 
C 1 57  ALA 57  57  57  ALA ALA C . n 
C 1 58  VAL 58  58  58  VAL VAL C . n 
C 1 59  ALA 59  59  59  ALA ALA C . n 
C 1 60  PRO 60  60  60  PRO PRO C . n 
C 1 61  ALA 61  61  61  ALA ALA C . n 
C 1 62  SER 62  62  62  SER SER C . n 
C 1 63  THR 63  63  63  THR THR C . n 
C 1 64  GLU 64  64  64  GLU GLU C . n 
C 1 65  GLU 65  65  65  GLU GLU C . n 
C 1 66  VAL 66  66  66  VAL VAL C . n 
C 1 67  GLN 67  67  67  GLN GLN C . n 
C 1 68  GLU 68  68  68  GLU GLU C . n 
C 1 69  ILE 69  69  69  ILE ILE C . n 
C 1 70  VAL 70  70  70  VAL VAL C . n 
C 1 71  ARG 71  71  71  ARG ARG C . n 
C 1 72  VAL 72  72  72  VAL VAL C . n 
C 1 73  ALA 73  73  73  ALA ALA C . n 
C 1 74  ASN 74  74  74  ASN ASN C . n 
C 1 75  GLU 75  75  75  GLU GLU C . n 
C 1 76  PHE 76  76  76  PHE PHE C . n 
C 1 77  GLY 77  77  77  GLY GLY C . n 
C 1 78  VAL 78  78  78  VAL VAL C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  LEU 80  80  80  LEU LEU C . n 
C 1 81  TRP 81  81  81  TRP TRP C . n 
C 1 82  PRO 82  82  82  PRO PRO C . n 
C 1 83  VAL 83  83  83  VAL VAL C . n 
C 1 84  SER 84  84  84  SER SER C . n 
C 1 85  ARG 85  85  85  ARG ARG C . n 
C 1 86  GLY 86  86  86  GLY GLY C . n 
C 1 87  LYS 87  87  87  LYS LYS C . n 
C 1 88  ASN 88  88  88  ASN ASN C . n 
C 1 89  PHE 89  89  89  PHE PHE C . n 
C 1 90  ALA 90  90  90  ALA ALA C . n 
C 1 91  TYR 91  91  91  TYR TYR C . n 
C 1 92  GLY 92  92  92  GLY GLY C . n 
C 1 93  GLY 93  93  93  GLY GLY C . n 
C 1 94  ALA 94  94  94  ALA ALA C . n 
C 1 95  ALA 95  95  95  ALA ALA C . n 
C 1 96  PRO 96  96  96  PRO PRO C . n 
C 1 97  VAL 97  97  97  VAL VAL C . n 
C 1 98  MET 98  98  98  MET MET C . n 
C 1 99  SER 99  99  99  SER SER C . n 
C 1 100 GLY 100 100 100 GLY GLY C . n 
C 1 101 THR 101 101 101 THR THR C . n 
C 1 102 VAL 102 102 102 VAL VAL C . n 
C 1 103 VAL 103 103 103 VAL VAL C . n 
C 1 104 LEU 104 104 104 LEU LEU C . n 
C 1 105 ASP 105 105 105 ASP ASP C . n 
C 1 106 MET 106 106 106 MET MET C . n 
C 1 107 ASN 107 107 107 ASN ASN C . n 
C 1 108 ARG 108 108 108 ARG ARG C . n 
C 1 109 MET 109 109 109 MET MET C . n 
C 1 110 ASN 110 110 110 ASN ASN C . n 
C 1 111 ARG 111 111 111 ARG ARG C . n 
C 1 112 ILE 112 112 112 ILE ILE C . n 
C 1 113 LEU 113 113 113 LEU LEU C . n 
C 1 114 GLU 114 114 114 GLU GLU C . n 
C 1 115 VAL 115 115 115 VAL VAL C . n 
C 1 116 ASN 116 116 116 ASN ASN C . n 
C 1 117 GLU 117 117 117 GLU GLU C . n 
C 1 118 GLU 118 118 118 GLU GLU C . n 
C 1 119 PHE 119 119 119 PHE PHE C . n 
C 1 120 GLY 120 120 120 GLY GLY C . n 
C 1 121 TYR 121 121 121 TYR TYR C . n 
C 1 122 ALA 122 122 122 ALA ALA C . n 
C 1 123 LEU 123 123 123 LEU LEU C . n 
C 1 124 VAL 124 124 124 VAL VAL C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 PRO 126 126 126 PRO PRO C . n 
C 1 127 GLY 127 127 127 GLY GLY C . n 
C 1 128 VAL 128 128 128 VAL VAL C . n 
C 1 129 SER 129 129 129 SER SER C . n 
C 1 130 TYR 130 130 130 TYR TYR C . n 
C 1 131 PHE 131 131 131 PHE PHE C . n 
C 1 132 GLU 132 132 132 GLU GLU C . n 
C 1 133 LEU 133 133 133 LEU LEU C . n 
C 1 134 TYR 134 134 134 TYR TYR C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 TYR 136 136 136 TYR TYR C . n 
C 1 137 ILE 137 137 137 ILE ILE C . n 
C 1 138 GLN 138 138 138 GLN GLN C . n 
C 1 139 GLU 139 139 139 GLU GLU C . n 
C 1 140 LYS 140 140 140 LYS LYS C . n 
C 1 141 GLY 141 141 141 GLY GLY C . n 
C 1 142 LEU 142 142 142 LEU LEU C . n 
C 1 143 LYS 143 143 143 LYS LYS C . n 
C 1 144 LEU 144 144 144 LEU LEU C . n 
C 1 145 TRP 145 145 145 TRP TRP C . n 
C 1 146 ILE 146 146 146 ILE ILE C . n 
C 1 147 ASP 147 147 147 ASP ASP C . n 
C 1 148 VAL 148 148 148 VAL VAL C . n 
C 1 149 PRO 149 149 149 PRO PRO C . n 
C 1 150 ASP 150 150 150 ASP ASP C . n 
C 1 151 ASN 151 151 151 ASN ASN C . n 
C 1 152 GLY 152 152 152 GLY GLY C . n 
C 1 153 TRP 153 153 153 TRP TRP C . n 
C 1 154 GLY 154 154 154 GLY GLY C . n 
C 1 155 SER 155 155 155 SER SER C . n 
C 1 156 VAL 156 156 156 VAL VAL C . n 
C 1 157 VAL 157 157 157 VAL VAL C . n 
C 1 158 GLY 158 158 158 GLY GLY C . n 
C 1 159 ASN 159 159 159 ASN ASN C . n 
C 1 160 ALA 160 160 160 ALA ALA C . n 
C 1 161 LEU 161 161 161 LEU LEU C . n 
C 1 162 ASP 162 162 162 ASP ASP C . n 
C 1 163 HIS 163 163 163 HIS HIS C . n 
C 1 164 GLY 164 164 164 GLY GLY C . n 
C 1 165 ILE 165 165 165 ILE ILE C . n 
C 1 166 GLY 166 166 166 GLY GLY C . n 
C 1 167 TYR 167 167 167 TYR TYR C . n 
C 1 168 THR 168 168 168 THR THR C . n 
C 1 169 PRO 169 169 169 PRO PRO C . n 
C 1 170 TYR 170 170 170 TYR TYR C . n 
C 1 171 GLY 171 171 171 GLY GLY C . n 
C 1 172 ASP 172 172 172 ASP ASP C . n 
C 1 173 HIS 173 173 173 HIS HIS C . n 
C 1 174 PHE 174 174 174 PHE PHE C . n 
C 1 175 ALA 175 175 175 ALA ALA C . n 
C 1 176 MET 176 176 176 MET MET C . n 
C 1 177 GLN 177 177 177 GLN GLN C . n 
C 1 178 CYS 178 178 178 CYS CYS C . n 
C 1 179 GLY 179 179 179 GLY GLY C . n 
C 1 180 MET 180 180 180 MET MET C . n 
C 1 181 GLU 181 181 181 GLU GLU C . n 
C 1 182 VAL 182 182 182 VAL VAL C . n 
C 1 183 VAL 183 183 183 VAL VAL C . n 
C 1 184 LEU 184 184 184 LEU LEU C . n 
C 1 185 PRO 185 185 185 PRO PRO C . n 
C 1 186 ASN 186 186 186 ASN ASN C . n 
C 1 187 GLY 187 187 187 GLY GLY C . n 
C 1 188 GLU 188 188 188 GLU GLU C . n 
C 1 189 VAL 189 189 189 VAL VAL C . n 
C 1 190 VAL 190 190 190 VAL VAL C . n 
C 1 191 ARG 191 191 191 ARG ARG C . n 
C 1 192 THR 192 192 192 THR THR C . n 
C 1 193 GLY 193 193 193 GLY GLY C . n 
C 1 194 MET 194 194 194 MET MET C . n 
C 1 195 GLY 195 195 195 GLY GLY C . n 
C 1 196 ALA 196 196 196 ALA ALA C . n 
C 1 197 MET 197 197 197 MET MET C . n 
C 1 198 PRO 198 198 198 PRO PRO C . n 
C 1 199 GLY 199 199 199 GLY GLY C . n 
C 1 200 ASN 200 200 200 ASN ASN C . n 
C 1 201 ASN 201 201 201 ASN ASN C . n 
C 1 202 THR 202 202 202 THR THR C . n 
C 1 203 TRP 203 203 203 TRP TRP C . n 
C 1 204 GLN 204 204 204 GLN GLN C . n 
C 1 205 LEU 205 205 205 LEU LEU C . n 
C 1 206 PHE 206 206 206 PHE PHE C . n 
C 1 207 LYS 207 207 207 LYS LYS C . n 
C 1 208 TYR 208 208 208 TYR TYR C . n 
C 1 209 GLY 209 209 209 GLY GLY C . n 
C 1 210 TYR 210 210 210 TYR TYR C . n 
C 1 211 GLY 211 211 211 GLY GLY C . n 
C 1 212 PRO 212 212 212 PRO PRO C . n 
C 1 213 TYR 213 213 213 TYR TYR C . n 
C 1 214 VAL 214 214 214 VAL VAL C . n 
C 1 215 ASP 215 215 215 ASP ASP C . n 
C 1 216 GLY 216 216 216 GLY GLY C . n 
C 1 217 ILE 217 217 217 ILE ILE C . n 
C 1 218 PHE 218 218 218 PHE PHE C . n 
C 1 219 SER 219 219 219 SER SER C . n 
C 1 220 GLN 220 220 220 GLN GLN C . n 
C 1 221 SER 221 221 221 SER SER C . n 
C 1 222 ASN 222 222 222 ASN ASN C . n 
C 1 223 PHE 223 223 223 PHE PHE C . n 
C 1 224 GLY 224 224 224 GLY GLY C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 VAL 226 226 226 VAL VAL C . n 
C 1 227 THR 227 227 227 THR THR C . n 
C 1 228 LYS 228 228 228 LYS LYS C . n 
C 1 229 MET 229 229 229 MET MET C . n 
C 1 230 GLY 230 230 230 GLY GLY C . n 
C 1 231 ILE 231 231 231 ILE ILE C . n 
C 1 232 TRP 232 232 232 TRP TRP C . n 
C 1 233 LEU 233 233 233 LEU LEU C . n 
C 1 234 MET 234 234 234 MET MET C . n 
C 1 235 PRO 235 235 235 PRO PRO C . n 
C 1 236 GLU 236 236 236 GLU GLU C . n 
C 1 237 PRO 237 237 237 PRO PRO C . n 
C 1 238 ALA 238 238 238 ALA ALA C . n 
C 1 239 GLY 239 239 239 GLY GLY C . n 
C 1 240 TYR 240 240 240 TYR TYR C . n 
C 1 241 ARG 241 241 241 ARG ARG C . n 
C 1 242 PRO 242 242 242 PRO PRO C . n 
C 1 243 TYR 243 243 243 TYR TYR C . n 
C 1 244 LEU 244 244 244 LEU LEU C . n 
C 1 245 ILE 245 245 245 ILE ILE C . n 
C 1 246 THR 246 246 246 THR THR C . n 
C 1 247 PHE 247 247 247 PHE PHE C . n 
C 1 248 GLU 248 248 248 GLU GLU C . n 
C 1 249 ASN 249 249 249 ASN ASN C . n 
C 1 250 GLU 250 250 250 GLU GLU C . n 
C 1 251 ASP 251 251 251 ASP ASP C . n 
C 1 252 ASP 252 252 252 ASP ASP C . n 
C 1 253 ILE 253 253 253 ILE ILE C . n 
C 1 254 GLU 254 254 254 GLU GLU C . n 
C 1 255 THR 255 255 255 THR THR C . n 
C 1 256 VAL 256 256 256 VAL VAL C . n 
C 1 257 THR 257 257 257 THR THR C . n 
C 1 258 GLU 258 258 258 GLU GLU C . n 
C 1 259 ARG 259 259 259 ARG ARG C . n 
C 1 260 LEU 260 260 260 LEU LEU C . n 
C 1 261 ARG 261 261 261 ARG ARG C . n 
C 1 262 PRO 262 262 262 PRO PRO C . n 
C 1 263 LEU 263 263 263 LEU LEU C . n 
C 1 264 LYS 264 264 264 LYS LYS C . n 
C 1 265 VAL 265 265 265 VAL VAL C . n 
C 1 266 ALA 266 266 266 ALA ALA C . n 
C 1 267 GLY 267 267 267 GLY GLY C . n 
C 1 268 VAL 268 268 268 VAL VAL C . n 
C 1 269 ILE 269 269 269 ILE ILE C . n 
C 1 270 GLN 270 270 270 GLN GLN C . n 
C 1 271 ASN 271 271 271 ASN ASN C . n 
C 1 272 GLY 272 272 272 GLY GLY C . n 
C 1 273 ALA 273 273 273 ALA ALA C . n 
C 1 274 THR 274 274 274 THR THR C . n 
C 1 275 VAL 275 275 275 VAL VAL C . n 
C 1 276 ARG 276 276 276 ARG ARG C . n 
C 1 277 SER 277 277 277 SER SER C . n 
C 1 278 LEU 278 278 278 LEU LEU C . n 
C 1 279 VAL 279 279 279 VAL VAL C . n 
C 1 280 LEU 280 280 280 LEU LEU C . n 
C 1 281 ASP 281 281 281 ASP ASP C . n 
C 1 282 ALA 282 282 282 ALA ALA C . n 
C 1 283 ALA 283 283 283 ALA ALA C . n 
C 1 284 ILE 284 284 284 ILE ILE C . n 
C 1 285 THR 285 285 285 THR THR C . n 
C 1 286 ARG 286 286 286 ARG ARG C . n 
C 1 287 THR 287 287 287 THR THR C . n 
C 1 288 LYS 288 288 288 LYS LYS C . n 
C 1 289 SER 289 289 289 SER SER C . n 
C 1 290 GLN 290 290 290 GLN GLN C . n 
C 1 291 TYR 291 291 291 TYR TYR C . n 
C 1 292 TYR 292 292 292 TYR TYR C . n 
C 1 293 ASP 293 293 293 ASP ASP C . n 
C 1 294 GLY 294 294 294 GLY GLY C . n 
C 1 295 ASP 295 295 295 ASP ASP C . n 
C 1 296 GLY 296 296 296 GLY GLY C . n 
C 1 297 PRO 297 297 297 PRO PRO C . n 
C 1 298 ILE 298 298 298 ILE ILE C . n 
C 1 299 PRO 299 299 299 PRO PRO C . n 
C 1 300 PRO 300 300 300 PRO PRO C . n 
C 1 301 SER 301 301 301 SER SER C . n 
C 1 302 VAL 302 302 302 VAL VAL C . n 
C 1 303 ALA 303 303 303 ALA ALA C . n 
C 1 304 LYS 304 304 304 LYS LYS C . n 
C 1 305 THR 305 305 305 THR THR C . n 
C 1 306 MET 306 306 306 MET MET C . n 
C 1 307 MET 307 307 307 MET MET C . n 
C 1 308 ALA 308 308 308 ALA ALA C . n 
C 1 309 ASP 309 309 309 ASP ASP C . n 
C 1 310 LEU 310 310 310 LEU LEU C . n 
C 1 311 ASP 311 311 311 ASP ASP C . n 
C 1 312 LEU 312 312 312 LEU LEU C . n 
C 1 313 GLY 313 313 313 GLY GLY C . n 
C 1 314 MET 314 314 314 MET MET C . n 
C 1 315 TRP 315 315 315 TRP TRP C . n 
C 1 316 ASN 316 316 316 ASN ASN C . n 
C 1 317 PHE 317 317 317 PHE PHE C . n 
C 1 318 CYS 318 318 318 CYS CYS C . n 
C 1 319 GLY 319 319 319 GLY GLY C . n 
C 1 320 ALA 320 320 320 ALA ALA C . n 
C 1 321 LEU 321 321 321 LEU LEU C . n 
C 1 322 TYR 322 322 322 TYR TYR C . n 
C 1 323 GLY 323 323 323 GLY GLY C . n 
C 1 324 PRO 324 324 324 PRO PRO C . n 
C 1 325 PRO 325 325 325 PRO PRO C . n 
C 1 326 PRO 326 326 326 PRO PRO C . n 
C 1 327 VAL 327 327 327 VAL VAL C . n 
C 1 328 MET 328 328 328 MET MET C . n 
C 1 329 ASP 329 329 329 ASP ASP C . n 
C 1 330 THR 330 330 330 THR THR C . n 
C 1 331 LEU 331 331 331 LEU LEU C . n 
C 1 332 TRP 332 332 332 TRP TRP C . n 
C 1 333 THR 333 333 333 THR THR C . n 
C 1 334 ALA 334 334 334 ALA ALA C . n 
C 1 335 ILE 335 335 335 ILE ILE C . n 
C 1 336 ARG 336 336 336 ARG ARG C . n 
C 1 337 ASP 337 337 337 ASP ASP C . n 
C 1 338 SER 338 338 338 SER SER C . n 
C 1 339 PHE 339 339 339 PHE PHE C . n 
C 1 340 ALA 340 340 340 ALA ALA C . n 
C 1 341 ASP 341 341 341 ASP ASP C . n 
C 1 342 ILE 342 342 342 ILE ILE C . n 
C 1 343 PRO 343 343 343 PRO PRO C . n 
C 1 344 GLY 344 344 344 GLY GLY C . n 
C 1 345 VAL 345 345 345 VAL VAL C . n 
C 1 346 LYS 346 346 346 LYS LYS C . n 
C 1 347 PHE 347 347 347 PHE PHE C . n 
C 1 348 TYR 348 348 348 TYR TYR C . n 
C 1 349 PHE 349 349 349 PHE PHE C . n 
C 1 350 PRO 350 350 350 PRO PRO C . n 
C 1 351 GLU 351 351 351 GLU GLU C . n 
C 1 352 ASP 352 352 352 ASP ASP C . n 
C 1 353 ARG 353 353 353 ARG ARG C . n 
C 1 354 ARG 354 354 354 ARG ARG C . n 
C 1 355 HIS 355 355 355 HIS HIS C . n 
C 1 356 LYS 356 356 356 LYS LYS C . n 
C 1 357 VAL 357 357 357 VAL VAL C . n 
C 1 358 ASP 358 358 358 ASP ASP C . n 
C 1 359 LEU 359 359 359 LEU LEU C . n 
C 1 360 LEU 360 360 360 LEU LEU C . n 
C 1 361 LEU 361 361 361 LEU LEU C . n 
C 1 362 HIS 362 362 362 HIS HIS C . n 
C 1 363 ARG 363 363 363 ARG ARG C . n 
C 1 364 ALA 364 364 364 ALA ALA C . n 
C 1 365 GLU 365 365 365 GLU GLU C . n 
C 1 366 THR 366 366 366 THR THR C . n 
C 1 367 MET 367 367 367 MET MET C . n 
C 1 368 LYS 368 368 368 LYS LYS C . n 
C 1 369 GLY 369 369 369 GLY GLY C . n 
C 1 370 VAL 370 370 370 VAL VAL C . n 
C 1 371 PRO 371 371 371 PRO PRO C . n 
C 1 372 LYS 372 372 372 LYS LYS C . n 
C 1 373 LEU 373 373 373 LEU LEU C . n 
C 1 374 THR 374 374 374 THR THR C . n 
C 1 375 GLU 375 375 375 GLU GLU C . n 
C 1 376 PHE 376 376 376 PHE PHE C . n 
C 1 377 ASN 377 377 377 ASN ASN C . n 
C 1 378 PHE 378 378 378 PHE PHE C . n 
C 1 379 LEU 379 379 379 LEU LEU C . n 
C 1 380 ASN 380 380 380 ASN ASN C . n 
C 1 381 TRP 381 381 381 TRP TRP C . n 
C 1 382 ASP 382 382 382 ASP ASP C . n 
C 1 383 GLY 383 383 383 GLY GLY C . n 
C 1 384 GLY 384 384 384 GLY GLY C . n 
C 1 385 GLY 385 385 385 GLY GLY C . n 
C 1 386 GLY 386 386 386 GLY GLY C . n 
C 1 387 HIS 387 387 387 HIS HIS C . n 
C 1 388 VAL 388 388 388 VAL VAL C . n 
C 1 389 GLY 389 389 389 GLY GLY C . n 
C 1 390 PHE 390 390 390 PHE PHE C . n 
C 1 391 SER 391 391 391 SER SER C . n 
C 1 392 PRO 392 392 392 PRO PRO C . n 
C 1 393 VAL 393 393 393 VAL VAL C . n 
C 1 394 SER 394 394 394 SER SER C . n 
C 1 395 PRO 395 395 395 PRO PRO C . n 
C 1 396 ILE 396 396 396 ILE ILE C . n 
C 1 397 THR 397 397 397 THR THR C . n 
C 1 398 GLY 398 398 398 GLY GLY C . n 
C 1 399 LYS 399 399 399 LYS LYS C . n 
C 1 400 ASP 400 400 400 ASP ASP C . n 
C 1 401 ALA 401 401 401 ALA ALA C . n 
C 1 402 ILE 402 402 402 ILE ILE C . n 
C 1 403 LYS 403 403 403 LYS LYS C . n 
C 1 404 GLN 404 404 404 GLN GLN C . n 
C 1 405 TYR 405 405 405 TYR TYR C . n 
C 1 406 ASN 406 406 406 ASN ASN C . n 
C 1 407 MET 407 407 407 MET MET C . n 
C 1 408 VAL 408 408 408 VAL VAL C . n 
C 1 409 SER 409 409 409 SER SER C . n 
C 1 410 SER 410 410 410 SER SER C . n 
C 1 411 ARG 411 411 411 ARG ARG C . n 
C 1 412 VAL 412 412 412 VAL VAL C . n 
C 1 413 ARG 413 413 413 ARG ARG C . n 
C 1 414 GLU 414 414 414 GLU GLU C . n 
C 1 415 TYR 415 415 415 TYR TYR C . n 
C 1 416 GLY 416 416 416 GLY GLY C . n 
C 1 417 PHE 417 417 417 PHE PHE C . n 
C 1 418 ASP 418 418 418 ASP ASP C . n 
C 1 419 TYR 419 419 419 TYR TYR C . n 
C 1 420 MET 420 420 420 MET MET C . n 
C 1 421 GLY 421 421 421 GLY GLY C . n 
C 1 422 LEU 422 422 422 LEU LEU C . n 
C 1 423 LEU 423 423 423 LEU LEU C . n 
C 1 424 ALA 424 424 424 ALA ALA C . n 
C 1 425 ILE 425 425 425 ILE ILE C . n 
C 1 426 GLY 426 426 426 GLY GLY C . n 
C 1 427 TRP 427 427 427 TRP TRP C . n 
C 1 428 ARG 428 428 428 ARG ARG C . n 
C 1 429 ASP 429 429 429 ASP ASP C . n 
C 1 430 LEU 430 430 430 LEU LEU C . n 
C 1 431 HIS 431 431 431 HIS HIS C . n 
C 1 432 HIS 432 432 432 HIS HIS C . n 
C 1 433 VAL 433 433 433 VAL VAL C . n 
C 1 434 THR 434 434 434 THR THR C . n 
C 1 435 VAL 435 435 435 VAL VAL C . n 
C 1 436 ILE 436 436 436 ILE ILE C . n 
C 1 437 VAL 437 437 437 VAL VAL C . n 
C 1 438 TYR 438 438 438 TYR TYR C . n 
C 1 439 ASP 439 439 439 ASP ASP C . n 
C 1 440 LYS 440 440 440 LYS LYS C . n 
C 1 441 THR 441 441 441 THR THR C . n 
C 1 442 ASP 442 442 442 ASP ASP C . n 
C 1 443 PRO 443 443 443 PRO PRO C . n 
C 1 444 ASP 444 444 444 ASP ASP C . n 
C 1 445 GLU 445 445 445 GLU GLU C . n 
C 1 446 ARG 446 446 446 ARG ARG C . n 
C 1 447 LYS 447 447 447 LYS LYS C . n 
C 1 448 LYS 448 448 448 LYS LYS C . n 
C 1 449 LEU 449 449 449 LEU LEU C . n 
C 1 450 ASP 450 450 450 ASP ASP C . n 
C 1 451 GLU 451 451 451 GLU GLU C . n 
C 1 452 LEU 452 452 452 LEU LEU C . n 
C 1 453 PHE 453 453 453 PHE PHE C . n 
C 1 454 ASN 454 454 454 ASN ASN C . n 
C 1 455 ILE 455 455 455 ILE ILE C . n 
C 1 456 LEU 456 456 456 LEU LEU C . n 
C 1 457 VAL 457 457 457 VAL VAL C . n 
C 1 458 ASP 458 458 458 ASP ASP C . n 
C 1 459 GLU 459 459 459 GLU GLU C . n 
C 1 460 ALA 460 460 460 ALA ALA C . n 
C 1 461 ALA 461 461 461 ALA ALA C . n 
C 1 462 ALA 462 462 462 ALA ALA C . n 
C 1 463 GLU 463 463 463 GLU GLU C . n 
C 1 464 GLY 464 464 464 GLY GLY C . n 
C 1 465 TYR 465 465 465 TYR TYR C . n 
C 1 466 GLY 466 466 466 GLY GLY C . n 
C 1 467 GLU 467 467 467 GLU GLU C . n 
C 1 468 TYR 468 468 468 TYR TYR C . n 
C 1 469 ARG 469 469 469 ARG ARG C . n 
C 1 470 THR 470 470 470 THR THR C . n 
C 1 471 HIS 471 471 471 HIS HIS C . n 
C 1 472 ILE 472 472 472 ILE ILE C . n 
C 1 473 ARG 473 473 473 ARG ARG C . n 
C 1 474 TYR 474 474 474 TYR TYR C . n 
C 1 475 MET 475 475 475 MET MET C . n 
C 1 476 ASP 476 476 476 ASP ASP C . n 
C 1 477 ARG 477 477 477 ARG ARG C . n 
C 1 478 ILE 478 478 478 ILE ILE C . n 
C 1 479 ALA 479 479 479 ALA ALA C . n 
C 1 480 LYS 480 480 480 LYS LYS C . n 
C 1 481 THR 481 481 481 THR THR C . n 
C 1 482 TYR 482 482 482 TYR TYR C . n 
C 1 483 SER 483 483 483 SER SER C . n 
C 1 484 TRP 484 484 484 TRP TRP C . n 
C 1 485 ASN 485 485 485 ASN ASN C . n 
C 1 486 ASP 486 486 486 ASP ASP C . n 
C 1 487 ASN 487 487 487 ASN ASN C . n 
C 1 488 ALA 488 488 488 ALA ALA C . n 
C 1 489 LEU 489 489 489 LEU LEU C . n 
C 1 490 TRP 490 490 490 TRP TRP C . n 
C 1 491 LYS 491 491 491 LYS LYS C . n 
C 1 492 MET 492 492 492 MET MET C . n 
C 1 493 HIS 493 493 493 HIS HIS C . n 
C 1 494 GLU 494 494 494 GLU GLU C . n 
C 1 495 THR 495 495 495 THR THR C . n 
C 1 496 ILE 496 496 496 ILE ILE C . n 
C 1 497 LYS 497 497 497 LYS LYS C . n 
C 1 498 ASP 498 498 498 ASP ASP C . n 
C 1 499 ALA 499 499 499 ALA ALA C . n 
C 1 500 LEU 500 500 500 LEU LEU C . n 
C 1 501 ASP 501 501 501 ASP ASP C . n 
C 1 502 PRO 502 502 502 PRO PRO C . n 
C 1 503 ASN 503 503 503 ASN ASN C . n 
C 1 504 GLY 504 504 504 GLY GLY C . n 
C 1 505 ILE 505 505 505 ILE ILE C . n 
C 1 506 LEU 506 506 506 LEU LEU C . n 
C 1 507 ALA 507 507 507 ALA ALA C . n 
C 1 508 PRO 508 508 508 PRO PRO C . n 
C 1 509 GLY 509 509 509 GLY GLY C . n 
C 1 510 LYS 510 510 510 LYS LYS C . n 
C 1 511 SER 511 511 511 SER SER C . n 
C 1 512 GLY 512 512 512 GLY GLY C . n 
C 1 513 ILE 513 513 513 ILE ILE C . n 
C 1 514 TRP 514 514 514 TRP TRP C . n 
C 1 515 GLY 515 515 515 GLY GLY C . n 
C 1 516 LYS 516 516 516 LYS LYS C . n 
C 1 517 ASN 517 517 517 ASN ASN C . n 
C 1 518 ARG 518 518 518 ARG ARG C . n 
C 1 519 ARG 519 519 519 ARG ARG C . n 
C 1 520 LYS 520 520 ?   ?   ?   C . n 
C 1 521 ALA 521 521 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        FAD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   FAD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 FAD 1   601 601 FAD FAD A . 
E 3 PEG 1   602 610 PEG PEG A . 
F 4 CL  1   603 1   CL  CL  A . 
G 4 CL  1   604 3   CL  CL  A . 
H 4 CL  1   605 4   CL  CL  A . 
I 2 FAD 1   601 601 FAD FAD B . 
J 3 PEG 1   602 607 PEG PEG B . 
K 3 PEG 1   603 611 PEG PEG B . 
L 4 CL  1   604 2   CL  CL  B . 
M 2 FAD 1   601 601 FAD FAD C . 
N 5 HOH 1   701 135 HOH HOH A . 
N 5 HOH 2   702 4   HOH HOH A . 
N 5 HOH 3   703 121 HOH HOH A . 
N 5 HOH 4   704 250 HOH HOH A . 
N 5 HOH 5   705 93  HOH HOH A . 
N 5 HOH 6   706 70  HOH HOH A . 
N 5 HOH 7   707 17  HOH HOH A . 
N 5 HOH 8   708 281 HOH HOH A . 
N 5 HOH 9   709 18  HOH HOH A . 
N 5 HOH 10  710 45  HOH HOH A . 
N 5 HOH 11  711 72  HOH HOH A . 
N 5 HOH 12  712 290 HOH HOH A . 
N 5 HOH 13  713 148 HOH HOH A . 
N 5 HOH 14  714 62  HOH HOH A . 
N 5 HOH 15  715 38  HOH HOH A . 
N 5 HOH 16  716 165 HOH HOH A . 
N 5 HOH 17  717 201 HOH HOH A . 
N 5 HOH 18  718 12  HOH HOH A . 
N 5 HOH 19  719 244 HOH HOH A . 
N 5 HOH 20  720 107 HOH HOH A . 
N 5 HOH 21  721 229 HOH HOH A . 
N 5 HOH 22  722 217 HOH HOH A . 
N 5 HOH 23  723 100 HOH HOH A . 
N 5 HOH 24  724 239 HOH HOH A . 
N 5 HOH 25  725 198 HOH HOH A . 
N 5 HOH 26  726 150 HOH HOH A . 
N 5 HOH 27  727 186 HOH HOH A . 
N 5 HOH 28  728 251 HOH HOH A . 
N 5 HOH 29  729 245 HOH HOH A . 
N 5 HOH 30  730 234 HOH HOH A . 
N 5 HOH 31  731 29  HOH HOH A . 
N 5 HOH 32  732 232 HOH HOH A . 
N 5 HOH 33  733 111 HOH HOH A . 
N 5 HOH 34  734 2   HOH HOH A . 
N 5 HOH 35  735 218 HOH HOH A . 
N 5 HOH 36  736 120 HOH HOH A . 
N 5 HOH 37  737 79  HOH HOH A . 
N 5 HOH 38  738 32  HOH HOH A . 
N 5 HOH 39  739 87  HOH HOH A . 
N 5 HOH 40  740 212 HOH HOH A . 
N 5 HOH 41  741 263 HOH HOH A . 
N 5 HOH 42  742 104 HOH HOH A . 
N 5 HOH 43  743 55  HOH HOH A . 
N 5 HOH 44  744 257 HOH HOH A . 
N 5 HOH 45  745 113 HOH HOH A . 
N 5 HOH 46  746 24  HOH HOH A . 
N 5 HOH 47  747 42  HOH HOH A . 
N 5 HOH 48  748 230 HOH HOH A . 
N 5 HOH 49  749 28  HOH HOH A . 
N 5 HOH 50  750 27  HOH HOH A . 
N 5 HOH 51  751 21  HOH HOH A . 
N 5 HOH 52  752 3   HOH HOH A . 
N 5 HOH 53  753 161 HOH HOH A . 
N 5 HOH 54  754 63  HOH HOH A . 
N 5 HOH 55  755 66  HOH HOH A . 
N 5 HOH 56  756 227 HOH HOH A . 
N 5 HOH 57  757 139 HOH HOH A . 
N 5 HOH 58  758 171 HOH HOH A . 
N 5 HOH 59  759 238 HOH HOH A . 
N 5 HOH 60  760 225 HOH HOH A . 
N 5 HOH 61  761 60  HOH HOH A . 
N 5 HOH 62  762 9   HOH HOH A . 
N 5 HOH 63  763 10  HOH HOH A . 
N 5 HOH 64  764 50  HOH HOH A . 
N 5 HOH 65  765 187 HOH HOH A . 
N 5 HOH 66  766 88  HOH HOH A . 
N 5 HOH 67  767 109 HOH HOH A . 
N 5 HOH 68  768 52  HOH HOH A . 
N 5 HOH 69  769 115 HOH HOH A . 
N 5 HOH 70  770 54  HOH HOH A . 
N 5 HOH 71  771 254 HOH HOH A . 
N 5 HOH 72  772 125 HOH HOH A . 
N 5 HOH 73  773 6   HOH HOH A . 
N 5 HOH 74  774 108 HOH HOH A . 
N 5 HOH 75  775 241 HOH HOH A . 
N 5 HOH 76  776 282 HOH HOH A . 
N 5 HOH 77  777 264 HOH HOH A . 
N 5 HOH 78  778 194 HOH HOH A . 
N 5 HOH 79  779 41  HOH HOH A . 
N 5 HOH 80  780 256 HOH HOH A . 
N 5 HOH 81  781 127 HOH HOH A . 
N 5 HOH 82  782 97  HOH HOH A . 
N 5 HOH 83  783 226 HOH HOH A . 
N 5 HOH 84  784 140 HOH HOH A . 
N 5 HOH 85  785 133 HOH HOH A . 
N 5 HOH 86  786 151 HOH HOH A . 
N 5 HOH 87  787 44  HOH HOH A . 
N 5 HOH 88  788 169 HOH HOH A . 
N 5 HOH 89  789 168 HOH HOH A . 
N 5 HOH 90  790 78  HOH HOH A . 
N 5 HOH 91  791 191 HOH HOH A . 
N 5 HOH 92  792 128 HOH HOH A . 
N 5 HOH 93  793 299 HOH HOH A . 
N 5 HOH 94  794 189 HOH HOH A . 
N 5 HOH 95  795 180 HOH HOH A . 
N 5 HOH 96  796 95  HOH HOH A . 
N 5 HOH 97  797 124 HOH HOH A . 
N 5 HOH 98  798 183 HOH HOH A . 
N 5 HOH 99  799 153 HOH HOH A . 
N 5 HOH 100 800 129 HOH HOH A . 
N 5 HOH 101 801 275 HOH HOH A . 
N 5 HOH 102 802 184 HOH HOH A . 
N 5 HOH 103 803 197 HOH HOH A . 
N 5 HOH 104 804 284 HOH HOH A . 
N 5 HOH 105 805 156 HOH HOH A . 
N 5 HOH 106 806 106 HOH HOH A . 
N 5 HOH 107 807 136 HOH HOH A . 
N 5 HOH 108 808 181 HOH HOH A . 
N 5 HOH 109 809 294 HOH HOH A . 
O 5 HOH 1   701 138 HOH HOH B . 
O 5 HOH 2   702 220 HOH HOH B . 
O 5 HOH 3   703 126 HOH HOH B . 
O 5 HOH 4   704 172 HOH HOH B . 
O 5 HOH 5   705 215 HOH HOH B . 
O 5 HOH 6   706 90  HOH HOH B . 
O 5 HOH 7   707 119 HOH HOH B . 
O 5 HOH 8   708 11  HOH HOH B . 
O 5 HOH 9   709 56  HOH HOH B . 
O 5 HOH 10  710 202 HOH HOH B . 
O 5 HOH 11  711 96  HOH HOH B . 
O 5 HOH 12  712 74  HOH HOH B . 
O 5 HOH 13  713 277 HOH HOH B . 
O 5 HOH 14  714 84  HOH HOH B . 
O 5 HOH 15  715 75  HOH HOH B . 
O 5 HOH 16  716 46  HOH HOH B . 
O 5 HOH 17  717 178 HOH HOH B . 
O 5 HOH 18  718 228 HOH HOH B . 
O 5 HOH 19  719 77  HOH HOH B . 
O 5 HOH 20  720 255 HOH HOH B . 
O 5 HOH 21  721 224 HOH HOH B . 
O 5 HOH 22  722 289 HOH HOH B . 
O 5 HOH 23  723 265 HOH HOH B . 
O 5 HOH 24  724 71  HOH HOH B . 
O 5 HOH 25  725 269 HOH HOH B . 
O 5 HOH 26  726 141 HOH HOH B . 
O 5 HOH 27  727 237 HOH HOH B . 
O 5 HOH 28  728 279 HOH HOH B . 
O 5 HOH 29  729 206 HOH HOH B . 
O 5 HOH 30  730 103 HOH HOH B . 
O 5 HOH 31  731 67  HOH HOH B . 
O 5 HOH 32  732 242 HOH HOH B . 
O 5 HOH 33  733 146 HOH HOH B . 
O 5 HOH 34  734 53  HOH HOH B . 
O 5 HOH 35  735 83  HOH HOH B . 
O 5 HOH 36  736 199 HOH HOH B . 
O 5 HOH 37  737 131 HOH HOH B . 
O 5 HOH 38  738 49  HOH HOH B . 
O 5 HOH 39  739 51  HOH HOH B . 
O 5 HOH 40  740 267 HOH HOH B . 
O 5 HOH 41  741 23  HOH HOH B . 
O 5 HOH 42  742 205 HOH HOH B . 
O 5 HOH 43  743 208 HOH HOH B . 
O 5 HOH 44  744 160 HOH HOH B . 
O 5 HOH 45  745 292 HOH HOH B . 
O 5 HOH 46  746 261 HOH HOH B . 
O 5 HOH 47  747 272 HOH HOH B . 
O 5 HOH 48  748 57  HOH HOH B . 
O 5 HOH 49  749 15  HOH HOH B . 
O 5 HOH 50  750 33  HOH HOH B . 
O 5 HOH 51  751 16  HOH HOH B . 
O 5 HOH 52  752 85  HOH HOH B . 
O 5 HOH 53  753 94  HOH HOH B . 
O 5 HOH 54  754 166 HOH HOH B . 
O 5 HOH 55  755 243 HOH HOH B . 
O 5 HOH 56  756 92  HOH HOH B . 
O 5 HOH 57  757 110 HOH HOH B . 
O 5 HOH 58  758 30  HOH HOH B . 
O 5 HOH 59  759 48  HOH HOH B . 
O 5 HOH 60  760 25  HOH HOH B . 
O 5 HOH 61  761 91  HOH HOH B . 
O 5 HOH 62  762 89  HOH HOH B . 
O 5 HOH 63  763 36  HOH HOH B . 
O 5 HOH 64  764 35  HOH HOH B . 
O 5 HOH 65  765 149 HOH HOH B . 
O 5 HOH 66  766 280 HOH HOH B . 
O 5 HOH 67  767 145 HOH HOH B . 
O 5 HOH 68  768 231 HOH HOH B . 
O 5 HOH 69  769 207 HOH HOH B . 
O 5 HOH 70  770 204 HOH HOH B . 
O 5 HOH 71  771 31  HOH HOH B . 
O 5 HOH 72  772 101 HOH HOH B . 
O 5 HOH 73  773 190 HOH HOH B . 
O 5 HOH 74  774 58  HOH HOH B . 
O 5 HOH 75  775 252 HOH HOH B . 
O 5 HOH 76  776 287 HOH HOH B . 
O 5 HOH 77  777 260 HOH HOH B . 
O 5 HOH 78  778 73  HOH HOH B . 
O 5 HOH 79  779 219 HOH HOH B . 
O 5 HOH 80  780 143 HOH HOH B . 
O 5 HOH 81  781 259 HOH HOH B . 
O 5 HOH 82  782 200 HOH HOH B . 
O 5 HOH 83  783 216 HOH HOH B . 
O 5 HOH 84  784 69  HOH HOH B . 
O 5 HOH 85  785 203 HOH HOH B . 
O 5 HOH 86  786 253 HOH HOH B . 
O 5 HOH 87  787 13  HOH HOH B . 
O 5 HOH 88  788 268 HOH HOH B . 
O 5 HOH 89  789 297 HOH HOH B . 
O 5 HOH 90  790 65  HOH HOH B . 
O 5 HOH 91  791 273 HOH HOH B . 
O 5 HOH 92  792 144 HOH HOH B . 
O 5 HOH 93  793 193 HOH HOH B . 
O 5 HOH 94  794 293 HOH HOH B . 
O 5 HOH 95  795 195 HOH HOH B . 
O 5 HOH 96  796 123 HOH HOH B . 
O 5 HOH 97  797 300 HOH HOH B . 
O 5 HOH 98  798 175 HOH HOH B . 
O 5 HOH 99  799 179 HOH HOH B . 
O 5 HOH 100 800 285 HOH HOH B . 
O 5 HOH 101 801 176 HOH HOH B . 
O 5 HOH 102 802 162 HOH HOH B . 
O 5 HOH 103 803 298 HOH HOH B . 
O 5 HOH 104 804 157 HOH HOH B . 
O 5 HOH 105 805 177 HOH HOH B . 
O 5 HOH 106 806 170 HOH HOH B . 
O 5 HOH 107 807 192 HOH HOH B . 
O 5 HOH 108 808 122 HOH HOH B . 
O 5 HOH 109 809 158 HOH HOH B . 
O 5 HOH 110 810 295 HOH HOH B . 
O 5 HOH 111 811 59  HOH HOH B . 
O 5 HOH 112 812 130 HOH HOH B . 
O 5 HOH 113 813 286 HOH HOH B . 
P 5 HOH 1   701 112 HOH HOH C . 
P 5 HOH 2   702 34  HOH HOH C . 
P 5 HOH 3   703 209 HOH HOH C . 
P 5 HOH 4   704 43  HOH HOH C . 
P 5 HOH 5   705 7   HOH HOH C . 
P 5 HOH 6   706 185 HOH HOH C . 
P 5 HOH 7   707 61  HOH HOH C . 
P 5 HOH 8   708 39  HOH HOH C . 
P 5 HOH 9   709 47  HOH HOH C . 
P 5 HOH 10  710 214 HOH HOH C . 
P 5 HOH 11  711 14  HOH HOH C . 
P 5 HOH 12  712 262 HOH HOH C . 
P 5 HOH 13  713 221 HOH HOH C . 
P 5 HOH 14  714 82  HOH HOH C . 
P 5 HOH 15  715 249 HOH HOH C . 
P 5 HOH 16  716 22  HOH HOH C . 
P 5 HOH 17  717 283 HOH HOH C . 
P 5 HOH 18  718 19  HOH HOH C . 
P 5 HOH 19  719 236 HOH HOH C . 
P 5 HOH 20  720 5   HOH HOH C . 
P 5 HOH 21  721 68  HOH HOH C . 
P 5 HOH 22  722 278 HOH HOH C . 
P 5 HOH 23  723 102 HOH HOH C . 
P 5 HOH 24  724 98  HOH HOH C . 
P 5 HOH 25  725 26  HOH HOH C . 
P 5 HOH 26  726 167 HOH HOH C . 
P 5 HOH 27  727 114 HOH HOH C . 
P 5 HOH 28  728 296 HOH HOH C . 
P 5 HOH 29  729 117 HOH HOH C . 
P 5 HOH 30  730 37  HOH HOH C . 
P 5 HOH 31  731 8   HOH HOH C . 
P 5 HOH 32  732 248 HOH HOH C . 
P 5 HOH 33  733 20  HOH HOH C . 
P 5 HOH 34  734 240 HOH HOH C . 
P 5 HOH 35  735 173 HOH HOH C . 
P 5 HOH 36  736 116 HOH HOH C . 
P 5 HOH 37  737 80  HOH HOH C . 
P 5 HOH 38  738 247 HOH HOH C . 
P 5 HOH 39  739 233 HOH HOH C . 
P 5 HOH 40  740 222 HOH HOH C . 
P 5 HOH 41  741 276 HOH HOH C . 
P 5 HOH 42  742 223 HOH HOH C . 
P 5 HOH 43  743 76  HOH HOH C . 
P 5 HOH 44  744 40  HOH HOH C . 
P 5 HOH 45  745 211 HOH HOH C . 
P 5 HOH 46  746 271 HOH HOH C . 
P 5 HOH 47  747 266 HOH HOH C . 
P 5 HOH 48  748 81  HOH HOH C . 
P 5 HOH 49  749 270 HOH HOH C . 
P 5 HOH 50  750 246 HOH HOH C . 
P 5 HOH 51  751 213 HOH HOH C . 
P 5 HOH 52  752 274 HOH HOH C . 
P 5 HOH 53  753 64  HOH HOH C . 
P 5 HOH 54  754 99  HOH HOH C . 
P 5 HOH 55  755 210 HOH HOH C . 
P 5 HOH 56  756 147 HOH HOH C . 
P 5 HOH 57  757 142 HOH HOH C . 
P 5 HOH 58  758 188 HOH HOH C . 
P 5 HOH 59  759 258 HOH HOH C . 
P 5 HOH 60  760 235 HOH HOH C . 
P 5 HOH 61  761 86  HOH HOH C . 
P 5 HOH 62  762 137 HOH HOH C . 
P 5 HOH 63  763 159 HOH HOH C . 
P 5 HOH 64  764 291 HOH HOH C . 
P 5 HOH 65  765 118 HOH HOH C . 
P 5 HOH 66  766 152 HOH HOH C . 
P 5 HOH 67  767 155 HOH HOH C . 
P 5 HOH 68  768 134 HOH HOH C . 
P 5 HOH 69  769 163 HOH HOH C . 
P 5 HOH 70  770 288 HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0403 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8S7T 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     89.525 
_cell.length_a_esd                 ? 
_cell.length_b                     142.426 
_cell.length_b_esd                 ? 
_cell.length_c                     286.436 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8S7T 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8S7T 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.61 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.91 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          EVAPORATION 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M NaCl and 20% w/v PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   7.5 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 2M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-06-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.999870 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE MASSIF-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.999870 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   MASSIF-1 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8S7T 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.10 
_reflns.d_resolution_low                               143.22 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     106762 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                20.1 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          14.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.02 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.143 
_reflns.pdbx_Rpim_I_all                                0.032 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       2145888 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.139 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.10 
_reflns_shell.d_res_low                                     2.14 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           107932 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             5214 
_reflns_shell.percent_possible_obs                          100.0 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               20.7 
_reflns_shell.pdbx_chi_squared                              0.97 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     1.5 
_reflns_shell.pdbx_Rrim_I_all                               2.407 
_reflns_shell.pdbx_Rpim_I_all                               0.526 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.553 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  2.349 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.14 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            1.17 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            -1.02 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               48.684 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.966 
_refine.correlation_coeff_Fo_to_Fc_free          0.947 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8S7T 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.10 
_refine.ls_d_res_low                             143.22 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     101143 
_refine.ls_number_reflns_R_free                  5544 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.96 
_refine.ls_percent_reflns_R_free                 5.2 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.18655 
_refine.ls_R_factor_R_free                       0.23168 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.18409 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.198 
_refine.pdbx_overall_ESU_R_Free                  0.176 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             5.765 
_refine.overall_SU_ML                            0.146 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.10 
_refine_hist.d_res_low                        143.22 
_refine_hist.number_atoms_solvent             292 
_refine_hist.number_atoms_total               12717 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        12241 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         184 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.006  0.012  12799 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  11695 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.369  1.651  17435 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.463  1.568  26956 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.147  5.000  1550  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 7.198  5.000  78    ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 14.490 10.000 1974  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.064  0.200  1826  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  14939 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  2966  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 3.705  4.797  6209  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.704  4.797  6209  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 4.819  8.613  7756  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.819  8.613  7757  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 4.349  5.181  6590  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 4.349  5.181  6591  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 6.299  9.358  9680  ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 7.651  48.28  15019 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 7.648  48.30  14982 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.100 
_refine_ls_shell.d_res_low                        2.155 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             381 
_refine_ls_shell.number_reflns_R_work             7447 
_refine_ls_shell.percent_reflns_obs               99.97 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.293 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.317 
# 
_struct.entry_id                     8S7T 
_struct.title                        'Vanillyl-alcohol dehydrogenase from Marinicaulis flavus: P151N mutant' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8S7T 
_struct_keywords.text            'FAD, flavin, oxidase, alcohol, enzyme mechanism, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 2 ? 
J N N 3 ? 
K N N 3 ? 
L N N 4 ? 
M N N 2 ? 
N N N 5 ? 
O N N 5 ? 
P N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A2S7K3M2_9PROT 
_struct_ref.pdbx_db_accession          A0A2S7K3M2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MAAPLPEGVSAEAMSSALDRFARIVGADWVFTEDKITPYEDPYTISNDETEHRPYAAVAPASTEEVQEIVRVANEFGVPL
WPVSRGKNFAYGGAAPVMSGTVVLDMNRMNRILEVNEEFGYALVEPGVSYFELYDYIQEKGLKLWIDVPDPGWGSVVGNA
LDHGIGYTPYGDHFAMQCGMEVVLPNGEVVRTGMGAMPGNNTWQLFKYGYGPYVDGIFSQSNFGVVTKMGIWLMPEPAGY
RPYLITFENEDDIETVTERLRPLKVAGVIQNGATVRSLVLDAAITRTKSQYYDGDGPIPPSVAKTMMADLDLGMWNFCGA
LYGPPPVMDTLWTAIRDSFADIPGVKFYFPEDRRHKVDLLLHRAETMKGVPKLTEFNFLNWDGGGGHVGFSPVSPITGKD
AIKQYNMVSSRVREYGFDYMGLLAIGWRDLHHVTVIVYDKTDPDERKKLDELFNILVDEAAAEGYGEYRTHIRYMDRIAK
TYSWNDNALWKMHETIKDALDPNGILAPGKSGIWGKNRRKA
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8S7T A 1 ? 521 ? A0A2S7K3M2 1 ? 521 ? 1 521 
2 1 8S7T B 1 ? 521 ? A0A2S7K3M2 1 ? 521 ? 1 521 
3 1 8S7T C 1 ? 521 ? A0A2S7K3M2 1 ? 521 ? 1 521 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8S7T ASN A 151 ? UNP A0A2S7K3M2 PRO 151 'engineered mutation' 151 1 
2 8S7T ASN B 151 ? UNP A0A2S7K3M2 PRO 151 'engineered mutation' 151 2 
3 8S7T ASN C 151 ? UNP A0A2S7K3M2 PRO 151 'engineered mutation' 151 3 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 10450 ? 
1 MORE         -123  ? 
1 'SSA (A^2)'  33170 ? 
2 'ABSA (A^2)' 10980 ? 
2 MORE         -97   ? 
2 'SSA (A^2)'  33240 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1,2 A,D,E,F,G,H,N     
2 1   B,C,I,J,K,L,M,O,P 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z   1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000 
2 'crystal symmetry operation' 4_555 x,-y,-z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 10  ? GLY A 26  ? SER A 10  GLY A 26  1 ? 17 
HELX_P HELX_P2  AA2 THR A 32  ? GLU A 40  ? THR A 32  GLU A 40  5 ? 9  
HELX_P HELX_P3  AA3 SER A 62  ? GLY A 77  ? SER A 62  GLY A 77  1 ? 16 
HELX_P HELX_P4  AA4 SER A 129 ? GLY A 141 ? SER A 129 GLY A 141 1 ? 13 
HELX_P HELX_P5  AA5 SER A 155 ? ASP A 162 ? SER A 155 ASP A 162 1 ? 8  
HELX_P HELX_P6  AA6 HIS A 173 ? ALA A 175 ? HIS A 173 ALA A 175 5 ? 3  
HELX_P HELX_P7  AA7 GLY A 193 ? MET A 197 ? GLY A 193 MET A 197 5 ? 5  
HELX_P HELX_P8  AA8 VAL A 214 ? SER A 219 ? VAL A 214 SER A 219 5 ? 6  
HELX_P HELX_P9  AA9 ASN A 249 ? ASP A 251 ? ASN A 249 ASP A 251 5 ? 3  
HELX_P HELX_P10 AB1 ASP A 252 ? ALA A 266 ? ASP A 252 ALA A 266 1 ? 15 
HELX_P HELX_P11 AB2 LEU A 278 ? ALA A 283 ? LEU A 278 ALA A 283 1 ? 6  
HELX_P HELX_P12 AB3 THR A 287 ? TYR A 291 ? THR A 287 TYR A 291 5 ? 5  
HELX_P HELX_P13 AB4 PRO A 299 ? ASP A 311 ? PRO A 299 ASP A 311 1 ? 13 
HELX_P HELX_P14 AB5 PRO A 324 ? ALA A 340 ? PRO A 324 ALA A 340 1 ? 17 
HELX_P HELX_P15 AB6 PHE A 349 ? ARG A 353 ? PHE A 349 ARG A 353 5 ? 5  
HELX_P HELX_P16 AB7 ASP A 358 ? MET A 367 ? ASP A 358 MET A 367 1 ? 10 
HELX_P HELX_P17 AB8 LEU A 373 ? TRP A 381 ? LEU A 373 TRP A 381 5 ? 9  
HELX_P HELX_P18 AB9 THR A 397 ? TYR A 415 ? THR A 397 TYR A 415 1 ? 19 
HELX_P HELX_P19 AC1 ASP A 442 ? GLU A 463 ? ASP A 442 GLU A 463 1 ? 22 
HELX_P HELX_P20 AC2 HIS A 471 ? ARG A 473 ? HIS A 471 ARG A 473 5 ? 3  
HELX_P HELX_P21 AC3 TYR A 474 ? THR A 481 ? TYR A 474 THR A 481 1 ? 8  
HELX_P HELX_P22 AC4 SER A 483 ? ASP A 501 ? SER A 483 ASP A 501 1 ? 19 
HELX_P HELX_P23 AC5 GLY A 509 ? ILE A 513 ? GLY A 509 ILE A 513 5 ? 5  
HELX_P HELX_P24 AC6 GLY A 515 ? ARG A 519 ? GLY A 515 ARG A 519 5 ? 5  
HELX_P HELX_P25 AC7 SER B 10  ? GLY B 26  ? SER B 10  GLY B 26  1 ? 17 
HELX_P HELX_P26 AC8 THR B 32  ? GLU B 40  ? THR B 32  GLU B 40  5 ? 9  
HELX_P HELX_P27 AC9 SER B 62  ? GLY B 77  ? SER B 62  GLY B 77  1 ? 16 
HELX_P HELX_P28 AD1 SER B 129 ? GLY B 141 ? SER B 129 GLY B 141 1 ? 13 
HELX_P HELX_P29 AD2 SER B 155 ? ASP B 162 ? SER B 155 ASP B 162 1 ? 8  
HELX_P HELX_P30 AD3 HIS B 173 ? ALA B 175 ? HIS B 173 ALA B 175 5 ? 3  
HELX_P HELX_P31 AD4 GLY B 193 ? MET B 197 ? GLY B 193 MET B 197 5 ? 5  
HELX_P HELX_P32 AD5 VAL B 214 ? SER B 219 ? VAL B 214 SER B 219 5 ? 6  
HELX_P HELX_P33 AD6 ASN B 249 ? ASP B 251 ? ASN B 249 ASP B 251 5 ? 3  
HELX_P HELX_P34 AD7 ASP B 252 ? ALA B 266 ? ASP B 252 ALA B 266 1 ? 15 
HELX_P HELX_P35 AD8 LEU B 278 ? ARG B 286 ? LEU B 278 ARG B 286 1 ? 9  
HELX_P HELX_P36 AD9 THR B 287 ? TYR B 291 ? THR B 287 TYR B 291 5 ? 5  
HELX_P HELX_P37 AE1 PRO B 299 ? ASP B 311 ? PRO B 299 ASP B 311 1 ? 13 
HELX_P HELX_P38 AE2 PRO B 324 ? SER B 338 ? PRO B 324 SER B 338 1 ? 15 
HELX_P HELX_P39 AE3 PHE B 349 ? ARG B 353 ? PHE B 349 ARG B 353 5 ? 5  
HELX_P HELX_P40 AE4 ASP B 358 ? MET B 367 ? ASP B 358 MET B 367 1 ? 10 
HELX_P HELX_P41 AE5 LEU B 373 ? TRP B 381 ? LEU B 373 TRP B 381 5 ? 9  
HELX_P HELX_P42 AE6 THR B 397 ? TYR B 415 ? THR B 397 TYR B 415 1 ? 19 
HELX_P HELX_P43 AE7 ASP B 442 ? GLU B 463 ? ASP B 442 GLU B 463 1 ? 22 
HELX_P HELX_P44 AE8 HIS B 471 ? ARG B 473 ? HIS B 471 ARG B 473 5 ? 3  
HELX_P HELX_P45 AE9 TYR B 474 ? LYS B 480 ? TYR B 474 LYS B 480 1 ? 7  
HELX_P HELX_P46 AF1 SER B 483 ? ASP B 501 ? SER B 483 ASP B 501 1 ? 19 
HELX_P HELX_P47 AF2 GLY B 509 ? ILE B 513 ? GLY B 509 ILE B 513 5 ? 5  
HELX_P HELX_P48 AF3 SER C 10  ? GLY C 26  ? SER C 10  GLY C 26  1 ? 17 
HELX_P HELX_P49 AF4 THR C 32  ? GLU C 40  ? THR C 32  GLU C 40  5 ? 9  
HELX_P HELX_P50 AF5 SER C 62  ? GLY C 77  ? SER C 62  GLY C 77  1 ? 16 
HELX_P HELX_P51 AF6 SER C 129 ? LYS C 140 ? SER C 129 LYS C 140 1 ? 12 
HELX_P HELX_P52 AF7 SER C 155 ? ASP C 162 ? SER C 155 ASP C 162 1 ? 8  
HELX_P HELX_P53 AF8 GLY C 193 ? MET C 197 ? GLY C 193 MET C 197 5 ? 5  
HELX_P HELX_P54 AF9 VAL C 214 ? SER C 219 ? VAL C 214 SER C 219 5 ? 6  
HELX_P HELX_P55 AG1 ASN C 249 ? ASP C 251 ? ASN C 249 ASP C 251 5 ? 3  
HELX_P HELX_P56 AG2 ASP C 252 ? ALA C 266 ? ASP C 252 ALA C 266 1 ? 15 
HELX_P HELX_P57 AG3 LEU C 278 ? ALA C 283 ? LEU C 278 ALA C 283 1 ? 6  
HELX_P HELX_P58 AG4 THR C 287 ? TYR C 291 ? THR C 287 TYR C 291 5 ? 5  
HELX_P HELX_P59 AG5 PRO C 299 ? ASP C 311 ? PRO C 299 ASP C 311 1 ? 13 
HELX_P HELX_P60 AG6 PRO C 324 ? SER C 338 ? PRO C 324 SER C 338 1 ? 15 
HELX_P HELX_P61 AG7 PHE C 349 ? ARG C 353 ? PHE C 349 ARG C 353 5 ? 5  
HELX_P HELX_P62 AG8 ASP C 358 ? MET C 367 ? ASP C 358 MET C 367 1 ? 10 
HELX_P HELX_P63 AG9 LEU C 373 ? TRP C 381 ? LEU C 373 TRP C 381 5 ? 9  
HELX_P HELX_P64 AH1 THR C 397 ? TYR C 415 ? THR C 397 TYR C 415 1 ? 19 
HELX_P HELX_P65 AH2 ASP C 442 ? GLU C 463 ? ASP C 442 GLU C 463 1 ? 22 
HELX_P HELX_P66 AH3 HIS C 471 ? ARG C 473 ? HIS C 471 ARG C 473 5 ? 3  
HELX_P HELX_P67 AH4 TYR C 474 ? TYR C 482 ? TYR C 474 TYR C 482 1 ? 9  
HELX_P HELX_P68 AH5 SER C 483 ? ASP C 501 ? SER C 483 ASP C 501 1 ? 19 
HELX_P HELX_P69 AH6 GLY C 509 ? ILE C 513 ? GLY C 509 ILE C 513 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
AA4 ? 7 ? 
AA5 ? 7 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 2 ? 
AA9 ? 7 ? 
AB1 ? 7 ? 
AB2 ? 4 ? 
AB3 ? 5 ? 
AB4 ? 2 ? 
AB5 ? 7 ? 
AB6 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 6 7 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB1 6 7 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? parallel      
AB2 3 4 ? parallel      
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB5 5 6 ? anti-parallel 
AB5 6 7 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB6 4 5 ? anti-parallel 
AB6 5 6 ? anti-parallel 
AB6 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 30  ? PHE A 31  ? VAL A 30  PHE A 31  
AA1 2 ALA A 56  ? VAL A 58  ? ALA A 56  VAL A 58  
AA1 3 VAL A 102 ? ASP A 105 ? VAL A 102 ASP A 105 
AA1 4 LEU A 80  ? VAL A 83  ? LEU A 80  VAL A 83  
AA2 1 ILE A 112 ? ASN A 116 ? ILE A 112 ASN A 116 
AA2 2 TYR A 121 ? VAL A 124 ? TYR A 121 VAL A 124 
AA2 3 VAL A 225 ? TRP A 232 ? VAL A 225 TRP A 232 
AA2 4 GLN A 177 ? VAL A 183 ? GLN A 177 VAL A 183 
AA2 5 VAL A 189 ? ARG A 191 ? VAL A 189 ARG A 191 
AA3 1 LEU A 144 ? TRP A 145 ? LEU A 144 TRP A 145 
AA3 2 MET A 234 ? PRO A 235 ? MET A 234 PRO A 235 
AA4 1 LYS A 346 ? TYR A 348 ? LYS A 346 TYR A 348 
AA4 2 TYR A 240 ? PHE A 247 ? TYR A 240 PHE A 247 
AA4 3 TRP A 315 ? TYR A 322 ? TRP A 315 TYR A 322 
AA4 4 ALA A 273 ? SER A 277 ? ALA A 273 SER A 277 
AA4 5 MET A 420 ? ILE A 425 ? MET A 420 ILE A 425 
AA4 6 ASP A 429 ? TYR A 438 ? ASP A 429 TYR A 438 
AA4 7 GLY A 386 ? PHE A 390 ? GLY A 386 PHE A 390 
AA5 1 LYS A 346 ? TYR A 348 ? LYS A 346 TYR A 348 
AA5 2 TYR A 240 ? PHE A 247 ? TYR A 240 PHE A 247 
AA5 3 TRP A 315 ? TYR A 322 ? TRP A 315 TYR A 322 
AA5 4 ALA A 273 ? SER A 277 ? ALA A 273 SER A 277 
AA5 5 MET A 420 ? ILE A 425 ? MET A 420 ILE A 425 
AA5 6 ASP A 429 ? TYR A 438 ? ASP A 429 TYR A 438 
AA5 7 VAL A 393 ? PRO A 395 ? VAL A 393 PRO A 395 
AA6 1 VAL B 30  ? PHE B 31  ? VAL B 30  PHE B 31  
AA6 2 ALA B 57  ? VAL B 58  ? ALA B 57  VAL B 58  
AA6 3 VAL B 102 ? ASP B 105 ? VAL B 102 ASP B 105 
AA6 4 LEU B 80  ? VAL B 83  ? LEU B 80  VAL B 83  
AA7 1 ILE B 112 ? ASN B 116 ? ILE B 112 ASN B 116 
AA7 2 TYR B 121 ? VAL B 124 ? TYR B 121 VAL B 124 
AA7 3 VAL B 225 ? TRP B 232 ? VAL B 225 TRP B 232 
AA7 4 GLN B 177 ? VAL B 183 ? GLN B 177 VAL B 183 
AA7 5 VAL B 189 ? ARG B 191 ? VAL B 189 ARG B 191 
AA8 1 LEU B 144 ? TRP B 145 ? LEU B 144 TRP B 145 
AA8 2 MET B 234 ? PRO B 235 ? MET B 234 PRO B 235 
AA9 1 LYS B 346 ? TYR B 348 ? LYS B 346 TYR B 348 
AA9 2 TYR B 240 ? PHE B 247 ? TYR B 240 PHE B 247 
AA9 3 TRP B 315 ? TYR B 322 ? TRP B 315 TYR B 322 
AA9 4 ALA B 273 ? SER B 277 ? ALA B 273 SER B 277 
AA9 5 MET B 420 ? ILE B 425 ? MET B 420 ILE B 425 
AA9 6 ASP B 429 ? TYR B 438 ? ASP B 429 TYR B 438 
AA9 7 GLY B 386 ? PHE B 390 ? GLY B 386 PHE B 390 
AB1 1 LYS B 346 ? TYR B 348 ? LYS B 346 TYR B 348 
AB1 2 TYR B 240 ? PHE B 247 ? TYR B 240 PHE B 247 
AB1 3 TRP B 315 ? TYR B 322 ? TRP B 315 TYR B 322 
AB1 4 ALA B 273 ? SER B 277 ? ALA B 273 SER B 277 
AB1 5 MET B 420 ? ILE B 425 ? MET B 420 ILE B 425 
AB1 6 ASP B 429 ? TYR B 438 ? ASP B 429 TYR B 438 
AB1 7 VAL B 393 ? PRO B 395 ? VAL B 393 PRO B 395 
AB2 1 VAL C 30  ? PHE C 31  ? VAL C 30  PHE C 31  
AB2 2 ALA C 56  ? VAL C 58  ? ALA C 56  VAL C 58  
AB2 3 VAL C 102 ? ASP C 105 ? VAL C 102 ASP C 105 
AB2 4 LEU C 80  ? VAL C 83  ? LEU C 80  VAL C 83  
AB3 1 ILE C 112 ? ASN C 116 ? ILE C 112 ASN C 116 
AB3 2 TYR C 121 ? VAL C 124 ? TYR C 121 VAL C 124 
AB3 3 VAL C 225 ? TRP C 232 ? VAL C 225 TRP C 232 
AB3 4 GLN C 177 ? VAL C 183 ? GLN C 177 VAL C 183 
AB3 5 VAL C 189 ? ARG C 191 ? VAL C 189 ARG C 191 
AB4 1 LEU C 144 ? TRP C 145 ? LEU C 144 TRP C 145 
AB4 2 MET C 234 ? PRO C 235 ? MET C 234 PRO C 235 
AB5 1 LYS C 346 ? TYR C 348 ? LYS C 346 TYR C 348 
AB5 2 TYR C 240 ? PHE C 247 ? TYR C 240 PHE C 247 
AB5 3 TRP C 315 ? TYR C 322 ? TRP C 315 TYR C 322 
AB5 4 THR C 274 ? SER C 277 ? THR C 274 SER C 277 
AB5 5 GLY C 421 ? ILE C 425 ? GLY C 421 ILE C 425 
AB5 6 ASP C 429 ? TYR C 438 ? ASP C 429 TYR C 438 
AB5 7 GLY C 386 ? PHE C 390 ? GLY C 386 PHE C 390 
AB6 1 LYS C 346 ? TYR C 348 ? LYS C 346 TYR C 348 
AB6 2 TYR C 240 ? PHE C 247 ? TYR C 240 PHE C 247 
AB6 3 TRP C 315 ? TYR C 322 ? TRP C 315 TYR C 322 
AB6 4 THR C 274 ? SER C 277 ? THR C 274 SER C 277 
AB6 5 GLY C 421 ? ILE C 425 ? GLY C 421 ILE C 425 
AB6 6 ASP C 429 ? TYR C 438 ? ASP C 429 TYR C 438 
AB6 7 VAL C 393 ? PRO C 395 ? VAL C 393 PRO C 395 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 31  ? N PHE A 31  O ALA A 57  ? O ALA A 57  
AA1 2 3 N ALA A 56  ? N ALA A 56  O VAL A 103 ? O VAL A 103 
AA1 3 4 O LEU A 104 ? O LEU A 104 N TRP A 81  ? N TRP A 81  
AA2 1 2 N ASN A 116 ? N ASN A 116 O TYR A 121 ? O TYR A 121 
AA2 2 3 N VAL A 124 ? N VAL A 124 O MET A 229 ? O MET A 229 
AA2 3 4 O VAL A 225 ? O VAL A 225 N VAL A 183 ? N VAL A 183 
AA2 4 5 N VAL A 182 ? N VAL A 182 O VAL A 190 ? O VAL A 190 
AA3 1 2 N TRP A 145 ? N TRP A 145 O MET A 234 ? O MET A 234 
AA4 1 2 O TYR A 348 ? O TYR A 348 N LEU A 244 ? N LEU A 244 
AA4 2 3 N ILE A 245 ? N ILE A 245 O PHE A 317 ? O PHE A 317 
AA4 3 4 O ASN A 316 ? O ASN A 316 N ARG A 276 ? N ARG A 276 
AA4 4 5 N SER A 277 ? N SER A 277 O GLY A 421 ? O GLY A 421 
AA4 5 6 N LEU A 422 ? N LEU A 422 O VAL A 433 ? O VAL A 433 
AA4 6 7 O THR A 434 ? O THR A 434 N PHE A 390 ? N PHE A 390 
AA5 1 2 O TYR A 348 ? O TYR A 348 N LEU A 244 ? N LEU A 244 
AA5 2 3 N ILE A 245 ? N ILE A 245 O PHE A 317 ? O PHE A 317 
AA5 3 4 O ASN A 316 ? O ASN A 316 N ARG A 276 ? N ARG A 276 
AA5 4 5 N SER A 277 ? N SER A 277 O GLY A 421 ? O GLY A 421 
AA5 5 6 N LEU A 422 ? N LEU A 422 O VAL A 433 ? O VAL A 433 
AA5 6 7 O LEU A 430 ? O LEU A 430 N SER A 394 ? N SER A 394 
AA6 1 2 N PHE B 31  ? N PHE B 31  O ALA B 57  ? O ALA B 57  
AA6 2 3 N VAL B 58  ? N VAL B 58  O ASP B 105 ? O ASP B 105 
AA6 3 4 O LEU B 104 ? O LEU B 104 N TRP B 81  ? N TRP B 81  
AA7 1 2 N GLU B 114 ? N GLU B 114 O LEU B 123 ? O LEU B 123 
AA7 2 3 N VAL B 124 ? N VAL B 124 O MET B 229 ? O MET B 229 
AA7 3 4 O VAL B 225 ? O VAL B 225 N VAL B 183 ? N VAL B 183 
AA7 4 5 N VAL B 182 ? N VAL B 182 O VAL B 190 ? O VAL B 190 
AA8 1 2 N TRP B 145 ? N TRP B 145 O MET B 234 ? O MET B 234 
AA9 1 2 O TYR B 348 ? O TYR B 348 N LEU B 244 ? N LEU B 244 
AA9 2 3 N ILE B 245 ? N ILE B 245 O PHE B 317 ? O PHE B 317 
AA9 3 4 O ASN B 316 ? O ASN B 316 N ARG B 276 ? N ARG B 276 
AA9 4 5 N SER B 277 ? N SER B 277 O GLY B 421 ? O GLY B 421 
AA9 5 6 N MET B 420 ? N MET B 420 O VAL B 435 ? O VAL B 435 
AA9 6 7 O THR B 434 ? O THR B 434 N PHE B 390 ? N PHE B 390 
AB1 1 2 O TYR B 348 ? O TYR B 348 N LEU B 244 ? N LEU B 244 
AB1 2 3 N ILE B 245 ? N ILE B 245 O PHE B 317 ? O PHE B 317 
AB1 3 4 O ASN B 316 ? O ASN B 316 N ARG B 276 ? N ARG B 276 
AB1 4 5 N SER B 277 ? N SER B 277 O GLY B 421 ? O GLY B 421 
AB1 5 6 N MET B 420 ? N MET B 420 O VAL B 435 ? O VAL B 435 
AB1 6 7 O LEU B 430 ? O LEU B 430 N SER B 394 ? N SER B 394 
AB2 1 2 N PHE C 31  ? N PHE C 31  O ALA C 57  ? O ALA C 57  
AB2 2 3 N ALA C 56  ? N ALA C 56  O VAL C 103 ? O VAL C 103 
AB2 3 4 O LEU C 104 ? O LEU C 104 N VAL C 83  ? N VAL C 83  
AB3 1 2 N ASN C 116 ? N ASN C 116 O TYR C 121 ? O TYR C 121 
AB3 2 3 N VAL C 124 ? N VAL C 124 O MET C 229 ? O MET C 229 
AB3 3 4 O GLY C 230 ? O GLY C 230 N GLY C 179 ? N GLY C 179 
AB3 4 5 N VAL C 182 ? N VAL C 182 O VAL C 190 ? O VAL C 190 
AB4 1 2 N TRP C 145 ? N TRP C 145 O MET C 234 ? O MET C 234 
AB5 1 2 O TYR C 348 ? O TYR C 348 N LEU C 244 ? N LEU C 244 
AB5 2 3 N ILE C 245 ? N ILE C 245 O PHE C 317 ? O PHE C 317 
AB5 3 4 O ASN C 316 ? O ASN C 316 N ARG C 276 ? N ARG C 276 
AB5 4 5 N SER C 277 ? N SER C 277 O GLY C 421 ? O GLY C 421 
AB5 5 6 N ALA C 424 ? N ALA C 424 O HIS C 431 ? O HIS C 431 
AB5 6 7 O THR C 434 ? O THR C 434 N PHE C 390 ? N PHE C 390 
AB6 1 2 O TYR C 348 ? O TYR C 348 N LEU C 244 ? N LEU C 244 
AB6 2 3 N ILE C 245 ? N ILE C 245 O PHE C 317 ? O PHE C 317 
AB6 3 4 O ASN C 316 ? O ASN C 316 N ARG C 276 ? N ARG C 276 
AB6 4 5 N SER C 277 ? N SER C 277 O GLY C 421 ? O GLY C 421 
AB6 5 6 N ALA C 424 ? N ALA C 424 O HIS C 431 ? O HIS C 431 
AB6 6 7 O LEU C 430 ? O LEU C 430 N SER C 394 ? N SER C 394 
# 
_pdbx_entry_details.entry_id                   8S7T 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NE2 C HIS 387 ? ? C8M C FAD 601 ? ? 1.36 
2 1 NE2 B HIS 387 ? ? C8M B FAD 601 ? ? 1.51 
3 1 NE2 A HIS 387 ? ? C8M A FAD 601 ? ? 1.54 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CB C HIS 387 ? ? CG C HIS 387 ? ? CD2 C HIS 387 ? ? 140.75 131.40 9.35  1.20 N 
2 1 CB C HIS 387 ? ? CG C HIS 387 ? ? ND1 C HIS 387 ? ? 113.11 121.40 -8.29 1.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 33  ? ? 56.45   -102.73 
2  1 TYR A 43  ? ? -111.09 69.90   
3  1 LYS A 87  ? ? -96.11  37.88   
4  1 ALA A 90  ? ? 92.23   -8.60   
5  1 TYR A 170 ? ? -94.10  32.70   
6  1 TRP A 427 ? ? -147.01 -64.64  
7  1 ALA A 507 ? ? 37.42   63.92   
8  1 GLU B 33  ? ? 59.51   -122.02 
9  1 TYR B 43  ? ? -113.75 66.89   
10 1 ALA B 90  ? ? 96.71   -10.80  
11 1 LYS B 143 ? ? -93.49  57.93   
12 1 TYR B 170 ? ? -90.49  38.47   
13 1 TRP B 427 ? ? -135.18 -62.61  
14 1 TYR B 482 ? ? -97.74  59.71   
15 1 ASN B 485 ? ? 60.62   61.49   
16 1 ALA B 507 ? ? 39.29   61.22   
17 1 GLU C 33  ? ? 55.80   -127.25 
18 1 TYR C 43  ? ? -108.13 79.66   
19 1 ALA C 90  ? ? 109.60  -21.09  
20 1 TYR C 170 ? ? -98.93  33.30   
21 1 GLN C 220 ? ? 38.02   54.46   
22 1 LYS C 356 ? ? -97.65  -64.06  
23 1 ASP C 358 ? ? -173.58 137.52  
24 1 ALA C 507 ? ? 30.15   64.41   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 23  ? ? 0.083 'SIDE CHAIN' 
2 1 ARG A 111 ? ? 0.076 'SIDE CHAIN' 
3 1 ARG B 477 ? ? 0.095 'SIDE CHAIN' 
4 1 ARG C 363 ? ? 0.087 'SIDE CHAIN' 
5 1 ARG C 477 ? ? 0.086 'SIDE CHAIN' 
6 1 ARG C 519 ? ? 0.085 'SIDE CHAIN' 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    B 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     800 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   O 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A LYS 520 ? A LYS 520 
4  1 Y 1 A ALA 521 ? A ALA 521 
5  1 Y 1 B MET 1   ? B MET 1   
6  1 Y 1 B LYS 520 ? B LYS 520 
7  1 Y 1 B ALA 521 ? B ALA 521 
8  1 Y 1 C MET 1   ? C MET 1   
9  1 Y 1 C LYS 520 ? C LYS 520 
10 1 Y 1 C ALA 521 ? C ALA 521 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
CL  CL     CL N N 74  
CYS N      N  N N 75  
CYS CA     C  N R 76  
CYS C      C  N N 77  
CYS O      O  N N 78  
CYS CB     C  N N 79  
CYS SG     S  N N 80  
CYS OXT    O  N N 81  
CYS H      H  N N 82  
CYS H2     H  N N 83  
CYS HA     H  N N 84  
CYS HB2    H  N N 85  
CYS HB3    H  N N 86  
CYS HG     H  N N 87  
CYS HXT    H  N N 88  
FAD PA     P  N R 89  
FAD O1A    O  N N 90  
FAD O2A    O  N N 91  
FAD O5B    O  N N 92  
FAD C5B    C  N N 93  
FAD C4B    C  N R 94  
FAD O4B    O  N N 95  
FAD C3B    C  N S 96  
FAD O3B    O  N N 97  
FAD C2B    C  N R 98  
FAD O2B    O  N N 99  
FAD C1B    C  N R 100 
FAD N9A    N  Y N 101 
FAD C8A    C  Y N 102 
FAD N7A    N  Y N 103 
FAD C5A    C  Y N 104 
FAD C6A    C  Y N 105 
FAD N6A    N  N N 106 
FAD N1A    N  Y N 107 
FAD C2A    C  Y N 108 
FAD N3A    N  Y N 109 
FAD C4A    C  Y N 110 
FAD N1     N  N N 111 
FAD C2     C  N N 112 
FAD O2     O  N N 113 
FAD N3     N  N N 114 
FAD C4     C  N N 115 
FAD O4     O  N N 116 
FAD C4X    C  N N 117 
FAD N5     N  N N 118 
FAD C5X    C  Y N 119 
FAD C6     C  Y N 120 
FAD C7     C  Y N 121 
FAD C7M    C  N N 122 
FAD C8     C  Y N 123 
FAD C8M    C  N N 124 
FAD C9     C  Y N 125 
FAD C9A    C  Y N 126 
FAD N10    N  N N 127 
FAD C10    C  N N 128 
FAD "C1'"  C  N N 129 
FAD "C2'"  C  N S 130 
FAD "O2'"  O  N N 131 
FAD "C3'"  C  N S 132 
FAD "O3'"  O  N N 133 
FAD "C4'"  C  N R 134 
FAD "O4'"  O  N N 135 
FAD "C5'"  C  N N 136 
FAD "O5'"  O  N N 137 
FAD P      P  N R 138 
FAD O1P    O  N N 139 
FAD O2P    O  N N 140 
FAD O3P    O  N N 141 
FAD HOA2   H  N N 142 
FAD H51A   H  N N 143 
FAD H52A   H  N N 144 
FAD H4B    H  N N 145 
FAD H3B    H  N N 146 
FAD HO3A   H  N N 147 
FAD H2B    H  N N 148 
FAD HO2A   H  N N 149 
FAD H1B    H  N N 150 
FAD H8A    H  N N 151 
FAD H61A   H  N N 152 
FAD H62A   H  N N 153 
FAD H2A    H  N N 154 
FAD HN3    H  N N 155 
FAD H6     H  N N 156 
FAD HM71   H  N N 157 
FAD HM72   H  N N 158 
FAD HM73   H  N N 159 
FAD HM81   H  N N 160 
FAD HM82   H  N N 161 
FAD HM83   H  N N 162 
FAD H9     H  N N 163 
FAD "H1'1" H  N N 164 
FAD "H1'2" H  N N 165 
FAD "H2'"  H  N N 166 
FAD "HO2'" H  N N 167 
FAD "H3'"  H  N N 168 
FAD "HO3'" H  N N 169 
FAD "H4'"  H  N N 170 
FAD "HO4'" H  N N 171 
FAD "H5'1" H  N N 172 
FAD "H5'2" H  N N 173 
FAD HOP2   H  N N 174 
GLN N      N  N N 175 
GLN CA     C  N S 176 
GLN C      C  N N 177 
GLN O      O  N N 178 
GLN CB     C  N N 179 
GLN CG     C  N N 180 
GLN CD     C  N N 181 
GLN OE1    O  N N 182 
GLN NE2    N  N N 183 
GLN OXT    O  N N 184 
GLN H      H  N N 185 
GLN H2     H  N N 186 
GLN HA     H  N N 187 
GLN HB2    H  N N 188 
GLN HB3    H  N N 189 
GLN HG2    H  N N 190 
GLN HG3    H  N N 191 
GLN HE21   H  N N 192 
GLN HE22   H  N N 193 
GLN HXT    H  N N 194 
GLU N      N  N N 195 
GLU CA     C  N S 196 
GLU C      C  N N 197 
GLU O      O  N N 198 
GLU CB     C  N N 199 
GLU CG     C  N N 200 
GLU CD     C  N N 201 
GLU OE1    O  N N 202 
GLU OE2    O  N N 203 
GLU OXT    O  N N 204 
GLU H      H  N N 205 
GLU H2     H  N N 206 
GLU HA     H  N N 207 
GLU HB2    H  N N 208 
GLU HB3    H  N N 209 
GLU HG2    H  N N 210 
GLU HG3    H  N N 211 
GLU HE2    H  N N 212 
GLU HXT    H  N N 213 
GLY N      N  N N 214 
GLY CA     C  N N 215 
GLY C      C  N N 216 
GLY O      O  N N 217 
GLY OXT    O  N N 218 
GLY H      H  N N 219 
GLY H2     H  N N 220 
GLY HA2    H  N N 221 
GLY HA3    H  N N 222 
GLY HXT    H  N N 223 
HIS N      N  N N 224 
HIS CA     C  N S 225 
HIS C      C  N N 226 
HIS O      O  N N 227 
HIS CB     C  N N 228 
HIS CG     C  Y N 229 
HIS ND1    N  Y N 230 
HIS CD2    C  Y N 231 
HIS CE1    C  Y N 232 
HIS NE2    N  Y N 233 
HIS OXT    O  N N 234 
HIS H      H  N N 235 
HIS H2     H  N N 236 
HIS HA     H  N N 237 
HIS HB2    H  N N 238 
HIS HB3    H  N N 239 
HIS HD1    H  N N 240 
HIS HD2    H  N N 241 
HIS HE1    H  N N 242 
HIS HE2    H  N N 243 
HIS HXT    H  N N 244 
HOH O      O  N N 245 
HOH H1     H  N N 246 
HOH H2     H  N N 247 
ILE N      N  N N 248 
ILE CA     C  N S 249 
ILE C      C  N N 250 
ILE O      O  N N 251 
ILE CB     C  N S 252 
ILE CG1    C  N N 253 
ILE CG2    C  N N 254 
ILE CD1    C  N N 255 
ILE OXT    O  N N 256 
ILE H      H  N N 257 
ILE H2     H  N N 258 
ILE HA     H  N N 259 
ILE HB     H  N N 260 
ILE HG12   H  N N 261 
ILE HG13   H  N N 262 
ILE HG21   H  N N 263 
ILE HG22   H  N N 264 
ILE HG23   H  N N 265 
ILE HD11   H  N N 266 
ILE HD12   H  N N 267 
ILE HD13   H  N N 268 
ILE HXT    H  N N 269 
LEU N      N  N N 270 
LEU CA     C  N S 271 
LEU C      C  N N 272 
LEU O      O  N N 273 
LEU CB     C  N N 274 
LEU CG     C  N N 275 
LEU CD1    C  N N 276 
LEU CD2    C  N N 277 
LEU OXT    O  N N 278 
LEU H      H  N N 279 
LEU H2     H  N N 280 
LEU HA     H  N N 281 
LEU HB2    H  N N 282 
LEU HB3    H  N N 283 
LEU HG     H  N N 284 
LEU HD11   H  N N 285 
LEU HD12   H  N N 286 
LEU HD13   H  N N 287 
LEU HD21   H  N N 288 
LEU HD22   H  N N 289 
LEU HD23   H  N N 290 
LEU HXT    H  N N 291 
LYS N      N  N N 292 
LYS CA     C  N S 293 
LYS C      C  N N 294 
LYS O      O  N N 295 
LYS CB     C  N N 296 
LYS CG     C  N N 297 
LYS CD     C  N N 298 
LYS CE     C  N N 299 
LYS NZ     N  N N 300 
LYS OXT    O  N N 301 
LYS H      H  N N 302 
LYS H2     H  N N 303 
LYS HA     H  N N 304 
LYS HB2    H  N N 305 
LYS HB3    H  N N 306 
LYS HG2    H  N N 307 
LYS HG3    H  N N 308 
LYS HD2    H  N N 309 
LYS HD3    H  N N 310 
LYS HE2    H  N N 311 
LYS HE3    H  N N 312 
LYS HZ1    H  N N 313 
LYS HZ2    H  N N 314 
LYS HZ3    H  N N 315 
LYS HXT    H  N N 316 
MET N      N  N N 317 
MET CA     C  N S 318 
MET C      C  N N 319 
MET O      O  N N 320 
MET CB     C  N N 321 
MET CG     C  N N 322 
MET SD     S  N N 323 
MET CE     C  N N 324 
MET OXT    O  N N 325 
MET H      H  N N 326 
MET H2     H  N N 327 
MET HA     H  N N 328 
MET HB2    H  N N 329 
MET HB3    H  N N 330 
MET HG2    H  N N 331 
MET HG3    H  N N 332 
MET HE1    H  N N 333 
MET HE2    H  N N 334 
MET HE3    H  N N 335 
MET HXT    H  N N 336 
PEG C1     C  N N 337 
PEG O1     O  N N 338 
PEG C2     C  N N 339 
PEG O2     O  N N 340 
PEG C3     C  N N 341 
PEG C4     C  N N 342 
PEG O4     O  N N 343 
PEG H11    H  N N 344 
PEG H12    H  N N 345 
PEG HO1    H  N N 346 
PEG H21    H  N N 347 
PEG H22    H  N N 348 
PEG H31    H  N N 349 
PEG H32    H  N N 350 
PEG H41    H  N N 351 
PEG H42    H  N N 352 
PEG HO4    H  N N 353 
PHE N      N  N N 354 
PHE CA     C  N S 355 
PHE C      C  N N 356 
PHE O      O  N N 357 
PHE CB     C  N N 358 
PHE CG     C  Y N 359 
PHE CD1    C  Y N 360 
PHE CD2    C  Y N 361 
PHE CE1    C  Y N 362 
PHE CE2    C  Y N 363 
PHE CZ     C  Y N 364 
PHE OXT    O  N N 365 
PHE H      H  N N 366 
PHE H2     H  N N 367 
PHE HA     H  N N 368 
PHE HB2    H  N N 369 
PHE HB3    H  N N 370 
PHE HD1    H  N N 371 
PHE HD2    H  N N 372 
PHE HE1    H  N N 373 
PHE HE2    H  N N 374 
PHE HZ     H  N N 375 
PHE HXT    H  N N 376 
PRO N      N  N N 377 
PRO CA     C  N S 378 
PRO C      C  N N 379 
PRO O      O  N N 380 
PRO CB     C  N N 381 
PRO CG     C  N N 382 
PRO CD     C  N N 383 
PRO OXT    O  N N 384 
PRO H      H  N N 385 
PRO HA     H  N N 386 
PRO HB2    H  N N 387 
PRO HB3    H  N N 388 
PRO HG2    H  N N 389 
PRO HG3    H  N N 390 
PRO HD2    H  N N 391 
PRO HD3    H  N N 392 
PRO HXT    H  N N 393 
SER N      N  N N 394 
SER CA     C  N S 395 
SER C      C  N N 396 
SER O      O  N N 397 
SER CB     C  N N 398 
SER OG     O  N N 399 
SER OXT    O  N N 400 
SER H      H  N N 401 
SER H2     H  N N 402 
SER HA     H  N N 403 
SER HB2    H  N N 404 
SER HB3    H  N N 405 
SER HG     H  N N 406 
SER HXT    H  N N 407 
THR N      N  N N 408 
THR CA     C  N S 409 
THR C      C  N N 410 
THR O      O  N N 411 
THR CB     C  N R 412 
THR OG1    O  N N 413 
THR CG2    C  N N 414 
THR OXT    O  N N 415 
THR H      H  N N 416 
THR H2     H  N N 417 
THR HA     H  N N 418 
THR HB     H  N N 419 
THR HG1    H  N N 420 
THR HG21   H  N N 421 
THR HG22   H  N N 422 
THR HG23   H  N N 423 
THR HXT    H  N N 424 
TRP N      N  N N 425 
TRP CA     C  N S 426 
TRP C      C  N N 427 
TRP O      O  N N 428 
TRP CB     C  N N 429 
TRP CG     C  Y N 430 
TRP CD1    C  Y N 431 
TRP CD2    C  Y N 432 
TRP NE1    N  Y N 433 
TRP CE2    C  Y N 434 
TRP CE3    C  Y N 435 
TRP CZ2    C  Y N 436 
TRP CZ3    C  Y N 437 
TRP CH2    C  Y N 438 
TRP OXT    O  N N 439 
TRP H      H  N N 440 
TRP H2     H  N N 441 
TRP HA     H  N N 442 
TRP HB2    H  N N 443 
TRP HB3    H  N N 444 
TRP HD1    H  N N 445 
TRP HE1    H  N N 446 
TRP HE3    H  N N 447 
TRP HZ2    H  N N 448 
TRP HZ3    H  N N 449 
TRP HH2    H  N N 450 
TRP HXT    H  N N 451 
TYR N      N  N N 452 
TYR CA     C  N S 453 
TYR C      C  N N 454 
TYR O      O  N N 455 
TYR CB     C  N N 456 
TYR CG     C  Y N 457 
TYR CD1    C  Y N 458 
TYR CD2    C  Y N 459 
TYR CE1    C  Y N 460 
TYR CE2    C  Y N 461 
TYR CZ     C  Y N 462 
TYR OH     O  N N 463 
TYR OXT    O  N N 464 
TYR H      H  N N 465 
TYR H2     H  N N 466 
TYR HA     H  N N 467 
TYR HB2    H  N N 468 
TYR HB3    H  N N 469 
TYR HD1    H  N N 470 
TYR HD2    H  N N 471 
TYR HE1    H  N N 472 
TYR HE2    H  N N 473 
TYR HH     H  N N 474 
TYR HXT    H  N N 475 
VAL N      N  N N 476 
VAL CA     C  N S 477 
VAL C      C  N N 478 
VAL O      O  N N 479 
VAL CB     C  N N 480 
VAL CG1    C  N N 481 
VAL CG2    C  N N 482 
VAL OXT    O  N N 483 
VAL H      H  N N 484 
VAL H2     H  N N 485 
VAL HA     H  N N 486 
VAL HB     H  N N 487 
VAL HG11   H  N N 488 
VAL HG12   H  N N 489 
VAL HG13   H  N N 490 
VAL HG21   H  N N 491 
VAL HG22   H  N N 492 
VAL HG23   H  N N 493 
VAL HXT    H  N N 494 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
FAD PA    O1A    doub N N 83  
FAD PA    O2A    sing N N 84  
FAD PA    O5B    sing N N 85  
FAD PA    O3P    sing N N 86  
FAD O2A   HOA2   sing N N 87  
FAD O5B   C5B    sing N N 88  
FAD C5B   C4B    sing N N 89  
FAD C5B   H51A   sing N N 90  
FAD C5B   H52A   sing N N 91  
FAD C4B   O4B    sing N N 92  
FAD C4B   C3B    sing N N 93  
FAD C4B   H4B    sing N N 94  
FAD O4B   C1B    sing N N 95  
FAD C3B   O3B    sing N N 96  
FAD C3B   C2B    sing N N 97  
FAD C3B   H3B    sing N N 98  
FAD O3B   HO3A   sing N N 99  
FAD C2B   O2B    sing N N 100 
FAD C2B   C1B    sing N N 101 
FAD C2B   H2B    sing N N 102 
FAD O2B   HO2A   sing N N 103 
FAD C1B   N9A    sing N N 104 
FAD C1B   H1B    sing N N 105 
FAD N9A   C8A    sing Y N 106 
FAD N9A   C4A    sing Y N 107 
FAD C8A   N7A    doub Y N 108 
FAD C8A   H8A    sing N N 109 
FAD N7A   C5A    sing Y N 110 
FAD C5A   C6A    sing Y N 111 
FAD C5A   C4A    doub Y N 112 
FAD C6A   N6A    sing N N 113 
FAD C6A   N1A    doub Y N 114 
FAD N6A   H61A   sing N N 115 
FAD N6A   H62A   sing N N 116 
FAD N1A   C2A    sing Y N 117 
FAD C2A   N3A    doub Y N 118 
FAD C2A   H2A    sing N N 119 
FAD N3A   C4A    sing Y N 120 
FAD N1    C2     sing N N 121 
FAD N1    C10    doub N N 122 
FAD C2    O2     doub N N 123 
FAD C2    N3     sing N N 124 
FAD N3    C4     sing N N 125 
FAD N3    HN3    sing N N 126 
FAD C4    O4     doub N N 127 
FAD C4    C4X    sing N N 128 
FAD C4X   N5     doub N N 129 
FAD C4X   C10    sing N N 130 
FAD N5    C5X    sing N N 131 
FAD C5X   C6     doub Y N 132 
FAD C5X   C9A    sing Y N 133 
FAD C6    C7     sing Y N 134 
FAD C6    H6     sing N N 135 
FAD C7    C7M    sing N N 136 
FAD C7    C8     doub Y N 137 
FAD C7M   HM71   sing N N 138 
FAD C7M   HM72   sing N N 139 
FAD C7M   HM73   sing N N 140 
FAD C8    C8M    sing N N 141 
FAD C8    C9     sing Y N 142 
FAD C8M   HM81   sing N N 143 
FAD C8M   HM82   sing N N 144 
FAD C8M   HM83   sing N N 145 
FAD C9    C9A    doub Y N 146 
FAD C9    H9     sing N N 147 
FAD C9A   N10    sing N N 148 
FAD N10   C10    sing N N 149 
FAD N10   "C1'"  sing N N 150 
FAD "C1'" "C2'"  sing N N 151 
FAD "C1'" "H1'1" sing N N 152 
FAD "C1'" "H1'2" sing N N 153 
FAD "C2'" "O2'"  sing N N 154 
FAD "C2'" "C3'"  sing N N 155 
FAD "C2'" "H2'"  sing N N 156 
FAD "O2'" "HO2'" sing N N 157 
FAD "C3'" "O3'"  sing N N 158 
FAD "C3'" "C4'"  sing N N 159 
FAD "C3'" "H3'"  sing N N 160 
FAD "O3'" "HO3'" sing N N 161 
FAD "C4'" "O4'"  sing N N 162 
FAD "C4'" "C5'"  sing N N 163 
FAD "C4'" "H4'"  sing N N 164 
FAD "O4'" "HO4'" sing N N 165 
FAD "C5'" "O5'"  sing N N 166 
FAD "C5'" "H5'1" sing N N 167 
FAD "C5'" "H5'2" sing N N 168 
FAD "O5'" P      sing N N 169 
FAD P     O1P    doub N N 170 
FAD P     O2P    sing N N 171 
FAD P     O3P    sing N N 172 
FAD O2P   HOP2   sing N N 173 
GLN N     CA     sing N N 174 
GLN N     H      sing N N 175 
GLN N     H2     sing N N 176 
GLN CA    C      sing N N 177 
GLN CA    CB     sing N N 178 
GLN CA    HA     sing N N 179 
GLN C     O      doub N N 180 
GLN C     OXT    sing N N 181 
GLN CB    CG     sing N N 182 
GLN CB    HB2    sing N N 183 
GLN CB    HB3    sing N N 184 
GLN CG    CD     sing N N 185 
GLN CG    HG2    sing N N 186 
GLN CG    HG3    sing N N 187 
GLN CD    OE1    doub N N 188 
GLN CD    NE2    sing N N 189 
GLN NE2   HE21   sing N N 190 
GLN NE2   HE22   sing N N 191 
GLN OXT   HXT    sing N N 192 
GLU N     CA     sing N N 193 
GLU N     H      sing N N 194 
GLU N     H2     sing N N 195 
GLU CA    C      sing N N 196 
GLU CA    CB     sing N N 197 
GLU CA    HA     sing N N 198 
GLU C     O      doub N N 199 
GLU C     OXT    sing N N 200 
GLU CB    CG     sing N N 201 
GLU CB    HB2    sing N N 202 
GLU CB    HB3    sing N N 203 
GLU CG    CD     sing N N 204 
GLU CG    HG2    sing N N 205 
GLU CG    HG3    sing N N 206 
GLU CD    OE1    doub N N 207 
GLU CD    OE2    sing N N 208 
GLU OE2   HE2    sing N N 209 
GLU OXT   HXT    sing N N 210 
GLY N     CA     sing N N 211 
GLY N     H      sing N N 212 
GLY N     H2     sing N N 213 
GLY CA    C      sing N N 214 
GLY CA    HA2    sing N N 215 
GLY CA    HA3    sing N N 216 
GLY C     O      doub N N 217 
GLY C     OXT    sing N N 218 
GLY OXT   HXT    sing N N 219 
HIS N     CA     sing N N 220 
HIS N     H      sing N N 221 
HIS N     H2     sing N N 222 
HIS CA    C      sing N N 223 
HIS CA    CB     sing N N 224 
HIS CA    HA     sing N N 225 
HIS C     O      doub N N 226 
HIS C     OXT    sing N N 227 
HIS CB    CG     sing N N 228 
HIS CB    HB2    sing N N 229 
HIS CB    HB3    sing N N 230 
HIS CG    ND1    sing Y N 231 
HIS CG    CD2    doub Y N 232 
HIS ND1   CE1    doub Y N 233 
HIS ND1   HD1    sing N N 234 
HIS CD2   NE2    sing Y N 235 
HIS CD2   HD2    sing N N 236 
HIS CE1   NE2    sing Y N 237 
HIS CE1   HE1    sing N N 238 
HIS NE2   HE2    sing N N 239 
HIS OXT   HXT    sing N N 240 
HOH O     H1     sing N N 241 
HOH O     H2     sing N N 242 
ILE N     CA     sing N N 243 
ILE N     H      sing N N 244 
ILE N     H2     sing N N 245 
ILE CA    C      sing N N 246 
ILE CA    CB     sing N N 247 
ILE CA    HA     sing N N 248 
ILE C     O      doub N N 249 
ILE C     OXT    sing N N 250 
ILE CB    CG1    sing N N 251 
ILE CB    CG2    sing N N 252 
ILE CB    HB     sing N N 253 
ILE CG1   CD1    sing N N 254 
ILE CG1   HG12   sing N N 255 
ILE CG1   HG13   sing N N 256 
ILE CG2   HG21   sing N N 257 
ILE CG2   HG22   sing N N 258 
ILE CG2   HG23   sing N N 259 
ILE CD1   HD11   sing N N 260 
ILE CD1   HD12   sing N N 261 
ILE CD1   HD13   sing N N 262 
ILE OXT   HXT    sing N N 263 
LEU N     CA     sing N N 264 
LEU N     H      sing N N 265 
LEU N     H2     sing N N 266 
LEU CA    C      sing N N 267 
LEU CA    CB     sing N N 268 
LEU CA    HA     sing N N 269 
LEU C     O      doub N N 270 
LEU C     OXT    sing N N 271 
LEU CB    CG     sing N N 272 
LEU CB    HB2    sing N N 273 
LEU CB    HB3    sing N N 274 
LEU CG    CD1    sing N N 275 
LEU CG    CD2    sing N N 276 
LEU CG    HG     sing N N 277 
LEU CD1   HD11   sing N N 278 
LEU CD1   HD12   sing N N 279 
LEU CD1   HD13   sing N N 280 
LEU CD2   HD21   sing N N 281 
LEU CD2   HD22   sing N N 282 
LEU CD2   HD23   sing N N 283 
LEU OXT   HXT    sing N N 284 
LYS N     CA     sing N N 285 
LYS N     H      sing N N 286 
LYS N     H2     sing N N 287 
LYS CA    C      sing N N 288 
LYS CA    CB     sing N N 289 
LYS CA    HA     sing N N 290 
LYS C     O      doub N N 291 
LYS C     OXT    sing N N 292 
LYS CB    CG     sing N N 293 
LYS CB    HB2    sing N N 294 
LYS CB    HB3    sing N N 295 
LYS CG    CD     sing N N 296 
LYS CG    HG2    sing N N 297 
LYS CG    HG3    sing N N 298 
LYS CD    CE     sing N N 299 
LYS CD    HD2    sing N N 300 
LYS CD    HD3    sing N N 301 
LYS CE    NZ     sing N N 302 
LYS CE    HE2    sing N N 303 
LYS CE    HE3    sing N N 304 
LYS NZ    HZ1    sing N N 305 
LYS NZ    HZ2    sing N N 306 
LYS NZ    HZ3    sing N N 307 
LYS OXT   HXT    sing N N 308 
MET N     CA     sing N N 309 
MET N     H      sing N N 310 
MET N     H2     sing N N 311 
MET CA    C      sing N N 312 
MET CA    CB     sing N N 313 
MET CA    HA     sing N N 314 
MET C     O      doub N N 315 
MET C     OXT    sing N N 316 
MET CB    CG     sing N N 317 
MET CB    HB2    sing N N 318 
MET CB    HB3    sing N N 319 
MET CG    SD     sing N N 320 
MET CG    HG2    sing N N 321 
MET CG    HG3    sing N N 322 
MET SD    CE     sing N N 323 
MET CE    HE1    sing N N 324 
MET CE    HE2    sing N N 325 
MET CE    HE3    sing N N 326 
MET OXT   HXT    sing N N 327 
PEG C1    O1     sing N N 328 
PEG C1    C2     sing N N 329 
PEG C1    H11    sing N N 330 
PEG C1    H12    sing N N 331 
PEG O1    HO1    sing N N 332 
PEG C2    O2     sing N N 333 
PEG C2    H21    sing N N 334 
PEG C2    H22    sing N N 335 
PEG O2    C3     sing N N 336 
PEG C3    C4     sing N N 337 
PEG C3    H31    sing N N 338 
PEG C3    H32    sing N N 339 
PEG C4    O4     sing N N 340 
PEG C4    H41    sing N N 341 
PEG C4    H42    sing N N 342 
PEG O4    HO4    sing N N 343 
PHE N     CA     sing N N 344 
PHE N     H      sing N N 345 
PHE N     H2     sing N N 346 
PHE CA    C      sing N N 347 
PHE CA    CB     sing N N 348 
PHE CA    HA     sing N N 349 
PHE C     O      doub N N 350 
PHE C     OXT    sing N N 351 
PHE CB    CG     sing N N 352 
PHE CB    HB2    sing N N 353 
PHE CB    HB3    sing N N 354 
PHE CG    CD1    doub Y N 355 
PHE CG    CD2    sing Y N 356 
PHE CD1   CE1    sing Y N 357 
PHE CD1   HD1    sing N N 358 
PHE CD2   CE2    doub Y N 359 
PHE CD2   HD2    sing N N 360 
PHE CE1   CZ     doub Y N 361 
PHE CE1   HE1    sing N N 362 
PHE CE2   CZ     sing Y N 363 
PHE CE2   HE2    sing N N 364 
PHE CZ    HZ     sing N N 365 
PHE OXT   HXT    sing N N 366 
PRO N     CA     sing N N 367 
PRO N     CD     sing N N 368 
PRO N     H      sing N N 369 
PRO CA    C      sing N N 370 
PRO CA    CB     sing N N 371 
PRO CA    HA     sing N N 372 
PRO C     O      doub N N 373 
PRO C     OXT    sing N N 374 
PRO CB    CG     sing N N 375 
PRO CB    HB2    sing N N 376 
PRO CB    HB3    sing N N 377 
PRO CG    CD     sing N N 378 
PRO CG    HG2    sing N N 379 
PRO CG    HG3    sing N N 380 
PRO CD    HD2    sing N N 381 
PRO CD    HD3    sing N N 382 
PRO OXT   HXT    sing N N 383 
SER N     CA     sing N N 384 
SER N     H      sing N N 385 
SER N     H2     sing N N 386 
SER CA    C      sing N N 387 
SER CA    CB     sing N N 388 
SER CA    HA     sing N N 389 
SER C     O      doub N N 390 
SER C     OXT    sing N N 391 
SER CB    OG     sing N N 392 
SER CB    HB2    sing N N 393 
SER CB    HB3    sing N N 394 
SER OG    HG     sing N N 395 
SER OXT   HXT    sing N N 396 
THR N     CA     sing N N 397 
THR N     H      sing N N 398 
THR N     H2     sing N N 399 
THR CA    C      sing N N 400 
THR CA    CB     sing N N 401 
THR CA    HA     sing N N 402 
THR C     O      doub N N 403 
THR C     OXT    sing N N 404 
THR CB    OG1    sing N N 405 
THR CB    CG2    sing N N 406 
THR CB    HB     sing N N 407 
THR OG1   HG1    sing N N 408 
THR CG2   HG21   sing N N 409 
THR CG2   HG22   sing N N 410 
THR CG2   HG23   sing N N 411 
THR OXT   HXT    sing N N 412 
TRP N     CA     sing N N 413 
TRP N     H      sing N N 414 
TRP N     H2     sing N N 415 
TRP CA    C      sing N N 416 
TRP CA    CB     sing N N 417 
TRP CA    HA     sing N N 418 
TRP C     O      doub N N 419 
TRP C     OXT    sing N N 420 
TRP CB    CG     sing N N 421 
TRP CB    HB2    sing N N 422 
TRP CB    HB3    sing N N 423 
TRP CG    CD1    doub Y N 424 
TRP CG    CD2    sing Y N 425 
TRP CD1   NE1    sing Y N 426 
TRP CD1   HD1    sing N N 427 
TRP CD2   CE2    doub Y N 428 
TRP CD2   CE3    sing Y N 429 
TRP NE1   CE2    sing Y N 430 
TRP NE1   HE1    sing N N 431 
TRP CE2   CZ2    sing Y N 432 
TRP CE3   CZ3    doub Y N 433 
TRP CE3   HE3    sing N N 434 
TRP CZ2   CH2    doub Y N 435 
TRP CZ2   HZ2    sing N N 436 
TRP CZ3   CH2    sing Y N 437 
TRP CZ3   HZ3    sing N N 438 
TRP CH2   HH2    sing N N 439 
TRP OXT   HXT    sing N N 440 
TYR N     CA     sing N N 441 
TYR N     H      sing N N 442 
TYR N     H2     sing N N 443 
TYR CA    C      sing N N 444 
TYR CA    CB     sing N N 445 
TYR CA    HA     sing N N 446 
TYR C     O      doub N N 447 
TYR C     OXT    sing N N 448 
TYR CB    CG     sing N N 449 
TYR CB    HB2    sing N N 450 
TYR CB    HB3    sing N N 451 
TYR CG    CD1    doub Y N 452 
TYR CG    CD2    sing Y N 453 
TYR CD1   CE1    sing Y N 454 
TYR CD1   HD1    sing N N 455 
TYR CD2   CE2    doub Y N 456 
TYR CD2   HD2    sing N N 457 
TYR CE1   CZ     doub Y N 458 
TYR CE1   HE1    sing N N 459 
TYR CE2   CZ     sing Y N 460 
TYR CE2   HE2    sing N N 461 
TYR CZ    OH     sing N N 462 
TYR OH    HH     sing N N 463 
TYR OXT   HXT    sing N N 464 
VAL N     CA     sing N N 465 
VAL N     H      sing N N 466 
VAL N     H2     sing N N 467 
VAL CA    C      sing N N 468 
VAL CA    CB     sing N N 469 
VAL CA    HA     sing N N 470 
VAL C     O      doub N N 471 
VAL C     OXT    sing N N 472 
VAL CB    CG1    sing N N 473 
VAL CB    CG2    sing N N 474 
VAL CB    HB     sing N N 475 
VAL CG1   HG11   sing N N 476 
VAL CG1   HG12   sing N N 477 
VAL CG1   HG13   sing N N 478 
VAL CG2   HG21   sing N N 479 
VAL CG2   HG22   sing N N 480 
VAL CG2   HG23   sing N N 481 
VAL OXT   HXT    sing N N 482 
# 
_pdbx_audit_support.funding_organization   'European Commission' 
_pdbx_audit_support.country                'European Union' 
_pdbx_audit_support.grant_number           'B-Ligzymes (GA 824017)' 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8S7T 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011170 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007021 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.003491 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N     . ALA A 1 3   ? -15.265 -28.604 -17.993  1.00 71.90  ? 3   ALA A N     1 
ATOM   2     C  CA    . ALA A 1 3   ? -15.084 -27.424 -17.107  1.00 68.59  ? 3   ALA A CA    1 
ATOM   3     C  C     . ALA A 1 3   ? -13.606 -27.031 -17.010  1.00 62.20  ? 3   ALA A C     1 
ATOM   4     O  O     . ALA A 1 3   ? -12.789 -27.738 -16.412  1.00 55.66  ? 3   ALA A O     1 
ATOM   5     C  CB    . ALA A 1 3   ? -15.664 -27.698 -15.741  1.00 78.08  ? 3   ALA A CB    1 
ATOM   6     N  N     . PRO A 1 4   ? -13.222 -25.859 -17.574  1.00 63.31  ? 4   PRO A N     1 
ATOM   7     C  CA    . PRO A 1 4   ? -11.890 -25.302 -17.344  1.00 64.01  ? 4   PRO A CA    1 
ATOM   8     C  C     . PRO A 1 4   ? -11.701 -24.902 -15.879  1.00 69.67  ? 4   PRO A C     1 
ATOM   9     O  O     . PRO A 1 4   ? -12.668 -24.578 -15.190  1.00 70.66  ? 4   PRO A O     1 
ATOM   10    C  CB    . PRO A 1 4   ? -11.800 -24.061 -18.256  1.00 63.86  ? 4   PRO A CB    1 
ATOM   11    C  CG    . PRO A 1 4   ? -13.061 -24.071 -19.126  1.00 63.97  ? 4   PRO A CG    1 
ATOM   12    C  CD    . PRO A 1 4   ? -14.046 -25.015 -18.461  1.00 66.86  ? 4   PRO A CD    1 
ATOM   13    N  N     . LEU A 1 5   ? -10.450 -24.945 -15.405  1.00 64.72  ? 5   LEU A N     1 
ATOM   14    C  CA    . LEU A 1 5   ? -10.074 -24.227 -14.205  1.00 66.89  ? 5   LEU A CA    1 
ATOM   15    C  C     . LEU A 1 5   ? -10.389 -22.753 -14.422  1.00 69.70  ? 5   LEU A C     1 
ATOM   16    O  O     . LEU A 1 5   ? -10.367 -22.275 -15.557  1.00 65.47  ? 5   LEU A O     1 
ATOM   17    C  CB    . LEU A 1 5   ? -8.581  -24.394 -13.922  1.00 66.70  ? 5   LEU A CB    1 
ATOM   18    C  CG    . LEU A 1 5   ? -8.134  -25.751 -13.391  1.00 69.68  ? 5   LEU A CG    1 
ATOM   19    C  CD1   . LEU A 1 5   ? -6.624  -25.760 -13.198  1.00 67.56  ? 5   LEU A CD1   1 
ATOM   20    C  CD2   . LEU A 1 5   ? -8.836  -26.098 -12.086  1.00 73.84  ? 5   LEU A CD2   1 
ATOM   21    N  N     . PRO A 1 6   ? -10.659 -21.987 -13.340  1.00 69.65  ? 6   PRO A N     1 
ATOM   22    C  CA    . PRO A 1 6   ? -10.862 -20.545 -13.461  1.00 64.82  ? 6   PRO A CA    1 
ATOM   23    C  C     . PRO A 1 6   ? -9.492  -19.894 -13.630  1.00 68.06  ? 6   PRO A C     1 
ATOM   24    O  O     . PRO A 1 6   ? -8.510  -20.316 -13.004  1.00 64.04  ? 6   PRO A O     1 
ATOM   25    C  CB    . PRO A 1 6   ? -11.551 -20.171 -12.141  1.00 69.83  ? 6   PRO A CB    1 
ATOM   26    C  CG    . PRO A 1 6   ? -11.025 -21.203 -11.141  1.00 68.40  ? 6   PRO A CG    1 
ATOM   27    C  CD    . PRO A 1 6   ? -10.695 -22.451 -11.942  1.00 64.88  ? 6   PRO A CD    1 
ATOM   28    N  N     . GLU A 1 7   ? -9.430  -18.880 -14.504  1.00 71.62  ? 7   GLU A N     1 
ATOM   29    C  CA    . GLU A 1 7   ? -8.165  -18.277 -14.886  1.00 68.64  ? 7   GLU A CA    1 
ATOM   30    C  C     . GLU A 1 7   ? -7.458  -17.754 -13.641  1.00 68.83  ? 7   GLU A C     1 
ATOM   31    O  O     . GLU A 1 7   ? -8.084  -17.196 -12.748  1.00 65.92  ? 7   GLU A O     1 
ATOM   32    C  CB    . GLU A 1 7   ? -8.378  -17.154 -15.898  1.00 75.38  ? 7   GLU A CB    1 
ATOM   33    C  CG    . GLU A 1 7   ? -7.137  -16.842 -16.711  1.00 80.28  ? 7   GLU A CG    1 
ATOM   34    C  CD    . GLU A 1 7   ? -7.264  -15.584 -17.549  1.00 89.29  ? 7   GLU A CD    1 
ATOM   35    O  OE1   . GLU A 1 7   ? -8.286  -15.446 -18.247  1.00 89.90  ? 7   GLU A OE1   1 
ATOM   36    O  OE2   . GLU A 1 7   ? -6.346  -14.745 -17.490  1.00 92.03  ? 7   GLU A OE2   1 
ATOM   37    N  N     . GLY A 1 8   ? -6.146  -17.977 -13.586  1.00 67.04  ? 8   GLY A N     1 
ATOM   38    C  CA    . GLY A 1 8   ? -5.328  -17.494 -12.494  1.00 63.20  ? 8   GLY A CA    1 
ATOM   39    C  C     . GLY A 1 8   ? -5.210  -18.511 -11.365  1.00 60.00  ? 8   GLY A C     1 
ATOM   40    O  O     . GLY A 1 8   ? -4.481  -18.272 -10.406  1.00 65.54  ? 8   GLY A O     1 
ATOM   41    N  N     . VAL A 1 9   ? -5.916  -19.641 -11.473  1.00 60.64  ? 9   VAL A N     1 
ATOM   42    C  CA    . VAL A 1 9   ? -6.006  -20.575 -10.357  1.00 62.11  ? 9   VAL A CA    1 
ATOM   43    C  C     . VAL A 1 9   ? -5.417  -21.906 -10.795  1.00 63.49  ? 9   VAL A C     1 
ATOM   44    O  O     . VAL A 1 9   ? -5.862  -22.476 -11.791  1.00 63.66  ? 9   VAL A O     1 
ATOM   45    C  CB    . VAL A 1 9   ? -7.454  -20.779 -9.859   1.00 63.72  ? 9   VAL A CB    1 
ATOM   46    C  CG1   . VAL A 1 9   ? -7.507  -21.736 -8.671   1.00 63.74  ? 9   VAL A CG1   1 
ATOM   47    C  CG2   . VAL A 1 9   ? -8.133  -19.462 -9.511   1.00 59.75  ? 9   VAL A CG2   1 
ATOM   48    N  N     . SER A 1 10  ? -4.465  -22.409 -10.007  1.00 64.22  ? 10  SER A N     1 
ATOM   49    C  CA    . SER A 1 10  ? -3.722  -23.600 -10.374  1.00 67.52  ? 10  SER A CA    1 
ATOM   50    C  C     . SER A 1 10  ? -4.515  -24.833 -9.963   1.00 73.65  ? 10  SER A C     1 
ATOM   51    O  O     . SER A 1 10  ? -5.438  -24.733 -9.160   1.00 73.35  ? 10  SER A O     1 
ATOM   52    C  CB    . SER A 1 10  ? -2.372  -23.601 -9.731   1.00 65.97  ? 10  SER A CB    1 
ATOM   53    O  OG    . SER A 1 10  ? -2.473  -24.008 -8.379   1.00 73.18  ? 10  SER A OG    1 
ATOM   54    N  N     . ALA A 1 11  ? -4.121  -25.994 -10.496  1.00 72.85  ? 11  ALA A N     1 
ATOM   55    C  CA    . ALA A 1 11  ? -4.707  -27.259 -10.084  1.00 73.55  ? 11  ALA A CA    1 
ATOM   56    C  C     . ALA A 1 11  ? -4.380  -27.551 -8.615   1.00 72.44  ? 11  ALA A C     1 
ATOM   57    O  O     . ALA A 1 11  ? -5.207  -28.117 -7.903   1.00 62.38  ? 11  ALA A O     1 
ATOM   58    C  CB    . ALA A 1 11  ? -4.242  -28.368 -11.000  1.00 69.63  ? 11  ALA A CB    1 
ATOM   59    N  N     . GLU A 1 12  ? -3.182  -27.153 -8.160   1.00 75.30  ? 12  GLU A N     1 
ATOM   60    C  CA    . GLU A 1 12  ? -2.753  -27.409 -6.790   1.00 77.68  ? 12  GLU A CA    1 
ATOM   61    C  C     . GLU A 1 12  ? -3.671  -26.645 -5.837   1.00 78.31  ? 12  GLU A C     1 
ATOM   62    O  O     . GLU A 1 12  ? -4.066  -27.172 -4.801   1.00 71.71  ? 12  GLU A O     1 
ATOM   63    C  CB    . GLU A 1 12  ? -1.306  -26.966 -6.537   1.00 85.16  ? 12  GLU A CB    1 
ATOM   64    C  CG    . GLU A 1 12  ? -0.247  -27.771 -7.281   1.00 91.99  ? 12  GLU A CG    1 
ATOM   65    C  CD    . GLU A 1 12  ? -0.362  -27.750 -8.798   1.00 95.25  ? 12  GLU A CD    1 
ATOM   66    O  OE1   . GLU A 1 12  ? -0.571  -28.831 -9.380   1.00 92.99  ? 12  GLU A OE1   1 
ATOM   67    O  OE2   . GLU A 1 12  ? -0.269  -26.651 -9.398   1.00 91.08  ? 12  GLU A OE2   1 
ATOM   68    N  N     . ALA A 1 13  ? -3.989  -25.396 -6.213   1.00 79.51  ? 13  ALA A N     1 
ATOM   69    C  CA    . ALA A 1 13  ? -4.821  -24.506 -5.416   1.00 78.15  ? 13  ALA A CA    1 
ATOM   70    C  C     . ALA A 1 13  ? -6.258  -25.026 -5.366   1.00 77.01  ? 13  ALA A C     1 
ATOM   71    O  O     . ALA A 1 13  ? -6.801  -25.213 -4.279   1.00 80.07  ? 13  ALA A O     1 
ATOM   72    C  CB    . ALA A 1 13  ? -4.758  -23.107 -5.983   1.00 75.80  ? 13  ALA A CB    1 
ATOM   73    N  N     . MET A 1 14  ? -6.843  -25.282 -6.549   1.00 75.36  ? 14  MET A N     1 
ATOM   74    C  CA    . MET A 1 14  ? -8.220  -25.736 -6.682   1.00 75.22  ? 14  MET A CA    1 
ATOM   75    C  C     . MET A 1 14  ? -8.399  -27.060 -5.956   1.00 79.57  ? 14  MET A C     1 
ATOM   76    O  O     . MET A 1 14  ? -9.486  -27.325 -5.446   1.00 80.95  ? 14  MET A O     1 
ATOM   77    C  CB    . MET A 1 14  ? -8.613  -25.921 -8.149   1.00 72.89  ? 14  MET A CB    1 
ATOM   78    C  CG    . MET A 1 14  ? -9.976  -26.587 -8.373   1.00 76.91  ? 14  MET A CG    1 
ATOM   79    S  SD    . MET A 1 14  ? -11.394 -25.637 -7.713   1.00 69.88  ? 14  MET A SD    1 
ATOM   80    C  CE    . MET A 1 14  ? -11.465 -24.276 -8.878   1.00 64.47  ? 14  MET A CE    1 
ATOM   81    N  N     . SER A 1 15  ? -7.327  -27.866 -5.924   1.00 79.94  ? 15  SER A N     1 
ATOM   82    C  CA    . SER A 1 15  ? -7.348  -29.179 -5.299   1.00 76.88  ? 15  SER A CA    1 
ATOM   83    C  C     . SER A 1 15  ? -7.272  -29.078 -3.772   1.00 70.23  ? 15  SER A C     1 
ATOM   84    O  O     . SER A 1 15  ? -7.988  -29.794 -3.075   1.00 68.33  ? 15  SER A O     1 
ATOM   85    C  CB    . SER A 1 15  ? -6.238  -30.041 -5.843   1.00 79.09  ? 15  SER A CB    1 
ATOM   86    O  OG    . SER A 1 15  ? -6.193  -31.275 -5.146   1.00 86.09  ? 15  SER A OG    1 
ATOM   87    N  N     . SER A 1 16  ? -6.384  -28.212 -3.260   1.00 68.20  ? 16  SER A N     1 
ATOM   88    C  CA    . SER A 1 16  ? -6.244  -27.981 -1.829   1.00 70.41  ? 16  SER A CA    1 
ATOM   89    C  C     . SER A 1 16  ? -7.520  -27.368 -1.248   1.00 72.54  ? 16  SER A C     1 
ATOM   90    O  O     . SER A 1 16  ? -7.879  -27.616 -0.098   1.00 79.05  ? 16  SER A O     1 
ATOM   91    C  CB    . SER A 1 16  ? -5.072  -27.087 -1.539   1.00 71.85  ? 16  SER A CB    1 
ATOM   92    O  OG    . SER A 1 16  ? -3.912  -27.531 -2.216   1.00 78.99  ? 16  SER A OG    1 
ATOM   93    N  N     . ALA A 1 17  ? -8.189  -26.535 -2.046   1.00 68.00  ? 17  ALA A N     1 
ATOM   94    C  CA    . ALA A 1 17  ? -9.400  -25.869 -1.606   1.00 64.89  ? 17  ALA A CA    1 
ATOM   95    C  C     . ALA A 1 17  ? -10.538 -26.883 -1.528   1.00 64.70  ? 17  ALA A C     1 
ATOM   96    O  O     . ALA A 1 17  ? -11.237 -26.949 -0.521   1.00 65.72  ? 17  ALA A O     1 
ATOM   97    C  CB    . ALA A 1 17  ? -9.719  -24.718 -2.533   1.00 58.79  ? 17  ALA A CB    1 
ATOM   98    N  N     . LEU A 1 18  ? -10.698 -27.685 -2.584   1.00 61.57  ? 18  LEU A N     1 
ATOM   99    C  CA    . LEU A 1 18  ? -11.792 -28.640 -2.648   1.00 68.15  ? 18  LEU A CA    1 
ATOM   100   C  C     . LEU A 1 18  ? -11.628 -29.634 -1.510   1.00 69.60  ? 18  LEU A C     1 
ATOM   101   O  O     . LEU A 1 18  ? -12.608 -30.099 -0.937   1.00 66.46  ? 18  LEU A O     1 
ATOM   102   C  CB    . LEU A 1 18  ? -11.801 -29.332 -4.015   1.00 73.35  ? 18  LEU A CB    1 
ATOM   103   C  CG    . LEU A 1 18  ? -12.387 -28.513 -5.170   1.00 85.33  ? 18  LEU A CG    1 
ATOM   104   C  CD1   . LEU A 1 18  ? -11.996 -29.099 -6.518   1.00 87.39  ? 18  LEU A CD1   1 
ATOM   105   C  CD2   . LEU A 1 18  ? -13.906 -28.430 -5.078   1.00 88.20  ? 18  LEU A CD2   1 
ATOM   106   N  N     . ASP A 1 19  ? -10.366 -29.905 -1.180   1.00 75.33  ? 19  ASP A N     1 
ATOM   107   C  CA    . ASP A 1 19  ? -9.998  -30.732 -0.048   1.00 78.28  ? 19  ASP A CA    1 
ATOM   108   C  C     . ASP A 1 19  ? -10.485 -30.084 1.249    1.00 70.86  ? 19  ASP A C     1 
ATOM   109   O  O     . ASP A 1 19  ? -11.137 -30.736 2.056    1.00 70.24  ? 19  ASP A O     1 
ATOM   110   C  CB    . ASP A 1 19  ? -8.486  -30.973 -0.082   1.00 94.33  ? 19  ASP A CB    1 
ATOM   111   C  CG    . ASP A 1 19  ? -7.895  -31.515 1.206    1.00 99.23  ? 19  ASP A CG    1 
ATOM   112   O  OD1   . ASP A 1 19  ? -8.166  -32.688 1.529    1.00 93.98  ? 19  ASP A OD1   1 
ATOM   113   O  OD2   . ASP A 1 19  ? -7.170  -30.753 1.878    1.00 109.30 ? 19  ASP A OD2   1 
ATOM   114   N  N     . ARG A 1 20  ? -10.176 -28.800 1.459    1.00 70.39  ? 20  ARG A N     1 
ATOM   115   C  CA    . ARG A 1 20  ? -10.551 -28.142 2.706    1.00 63.95  ? 20  ARG A CA    1 
ATOM   116   C  C     . ARG A 1 20  ? -12.065 -27.923 2.802    1.00 62.05  ? 20  ARG A C     1 
ATOM   117   O  O     . ARG A 1 20  ? -12.633 -28.037 3.887    1.00 66.10  ? 20  ARG A O     1 
ATOM   118   C  CB    . ARG A 1 20  ? -9.781  -26.838 2.883    1.00 65.96  ? 20  ARG A CB    1 
ATOM   119   C  CG    . ARG A 1 20  ? -8.444  -27.005 3.584    1.00 68.96  ? 20  ARG A CG    1 
ATOM   120   C  CD    . ARG A 1 20  ? -8.050  -25.700 4.245    1.00 75.89  ? 20  ARG A CD    1 
ATOM   121   N  NE    . ARG A 1 20  ? -6.638  -25.600 4.576    1.00 87.15  ? 20  ARG A NE    1 
ATOM   122   C  CZ    . ARG A 1 20  ? -5.637  -25.823 3.726    1.00 93.62  ? 20  ARG A CZ    1 
ATOM   123   N  NH1   . ARG A 1 20  ? -5.876  -26.330 2.527    1.00 99.33  ? 20  ARG A NH1   1 
ATOM   124   N  NH2   . ARG A 1 20  ? -4.391  -25.577 4.095    1.00 85.20  ? 20  ARG A NH2   1 
ATOM   125   N  N     . PHE A 1 21  ? -12.734 -27.648 1.676    1.00 61.84  ? 21  PHE A N     1 
ATOM   126   C  CA    . PHE A 1 21  ? -14.193 -27.588 1.663    1.00 62.14  ? 21  PHE A CA    1 
ATOM   127   C  C     . PHE A 1 21  ? -14.776 -28.895 2.201    1.00 67.96  ? 21  PHE A C     1 
ATOM   128   O  O     . PHE A 1 21  ? -15.664 -28.880 3.050    1.00 63.54  ? 21  PHE A O     1 
ATOM   129   C  CB    . PHE A 1 21  ? -14.753 -27.333 0.258    1.00 55.85  ? 21  PHE A CB    1 
ATOM   130   C  CG    . PHE A 1 21  ? -14.416 -26.005 -0.385   1.00 58.92  ? 21  PHE A CG    1 
ATOM   131   C  CD1   . PHE A 1 21  ? -13.949 -24.923 0.355    1.00 59.76  ? 21  PHE A CD1   1 
ATOM   132   C  CD2   . PHE A 1 21  ? -14.546 -25.846 -1.756   1.00 60.83  ? 21  PHE A CD2   1 
ATOM   133   C  CE1   . PHE A 1 21  ? -13.623 -23.727 -0.264   1.00 58.22  ? 21  PHE A CE1   1 
ATOM   134   C  CE2   . PHE A 1 21  ? -14.224 -24.643 -2.372   1.00 61.23  ? 21  PHE A CE2   1 
ATOM   135   C  CZ    . PHE A 1 21  ? -13.771 -23.586 -1.626   1.00 56.34  ? 21  PHE A CZ    1 
ATOM   136   N  N     . ALA A 1 22  ? -14.270 -30.020 1.677    1.00 78.20  ? 22  ALA A N     1 
ATOM   137   C  CA    . ALA A 1 22  ? -14.703 -31.355 2.068    1.00 74.76  ? 22  ALA A CA    1 
ATOM   138   C  C     . ALA A 1 22  ? -14.566 -31.555 3.575    1.00 65.58  ? 22  ALA A C     1 
ATOM   139   O  O     . ALA A 1 22  ? -15.424 -32.178 4.193    1.00 61.34  ? 22  ALA A O     1 
ATOM   140   C  CB    . ALA A 1 22  ? -13.902 -32.388 1.316    1.00 81.32  ? 22  ALA A CB    1 
ATOM   141   N  N     . ARG A 1 23  ? -13.487 -31.023 4.162    1.00 61.38  ? 23  ARG A N     1 
ATOM   142   C  CA    . ARG A 1 23  ? -13.305 -31.113 5.600    1.00 68.48  ? 23  ARG A CA    1 
ATOM   143   C  C     . ARG A 1 23  ? -14.380 -30.298 6.314    1.00 66.71  ? 23  ARG A C     1 
ATOM   144   O  O     . ARG A 1 23  ? -14.820 -30.686 7.389    1.00 69.38  ? 23  ARG A O     1 
ATOM   145   C  CB    . ARG A 1 23  ? -11.910 -30.642 6.025    1.00 72.17  ? 23  ARG A CB    1 
ATOM   146   C  CG    . ARG A 1 23  ? -11.539 -30.999 7.463    1.00 78.64  ? 23  ARG A CG    1 
ATOM   147   C  CD    . ARG A 1 23  ? -10.046 -30.863 7.718    1.00 90.84  ? 23  ARG A CD    1 
ATOM   148   N  NE    . ARG A 1 23  ? -9.293  -31.496 6.634    1.00 103.96 ? 23  ARG A NE    1 
ATOM   149   C  CZ    . ARG A 1 23  ? -8.391  -30.897 5.855    1.00 101.68 ? 23  ARG A CZ    1 
ATOM   150   N  NH1   . ARG A 1 23  ? -7.811  -29.771 6.236    1.00 103.46 ? 23  ARG A NH1   1 
ATOM   151   N  NH2   . ARG A 1 23  ? -8.021  -31.465 4.718    1.00 94.46  ? 23  ARG A NH2   1 
ATOM   152   N  N     . ILE A 1 24  ? -14.790 -29.172 5.716    1.00 66.30  ? 24  ILE A N     1 
ATOM   153   C  CA    . ILE A 1 24  ? -15.724 -28.265 6.365    1.00 57.82  ? 24  ILE A CA    1 
ATOM   154   C  C     . ILE A 1 24  ? -17.130 -28.844 6.336    1.00 52.81  ? 24  ILE A C     1 
ATOM   155   O  O     . ILE A 1 24  ? -17.831 -28.771 7.339    1.00 56.86  ? 24  ILE A O     1 
ATOM   156   C  CB    . ILE A 1 24  ? -15.696 -26.862 5.727    1.00 54.83  ? 24  ILE A CB    1 
ATOM   157   C  CG1   . ILE A 1 24  ? -14.387 -26.142 6.053    1.00 52.21  ? 24  ILE A CG1   1 
ATOM   158   C  CG2   . ILE A 1 24  ? -16.909 -26.060 6.190    1.00 54.99  ? 24  ILE A CG2   1 
ATOM   159   C  CD1   . ILE A 1 24  ? -14.093 -24.960 5.163    1.00 55.58  ? 24  ILE A CD1   1 
ATOM   160   N  N     . VAL A 1 25  ? -17.566 -29.348 5.177    1.00 52.72  ? 25  VAL A N     1 
ATOM   161   C  CA    . VAL A 1 25  ? -18.965 -29.705 5.014    1.00 53.42  ? 25  VAL A CA    1 
ATOM   162   C  C     . VAL A 1 25  ? -19.127 -31.221 4.951    1.00 57.24  ? 25  VAL A C     1 
ATOM   163   O  O     . VAL A 1 25  ? -20.240 -31.708 4.763    1.00 51.83  ? 25  VAL A O     1 
ATOM   164   C  CB    . VAL A 1 25  ? -19.580 -29.050 3.762    1.00 53.80  ? 25  VAL A CB    1 
ATOM   165   C  CG1   . VAL A 1 25  ? -19.406 -27.534 3.773    1.00 53.26  ? 25  VAL A CG1   1 
ATOM   166   C  CG2   . VAL A 1 25  ? -19.041 -29.652 2.468    1.00 57.55  ? 25  VAL A CG2   1 
ATOM   167   N  N     . GLY A 1 26  ? -18.016 -31.959 5.068    1.00 63.00  ? 26  GLY A N     1 
ATOM   168   C  CA    . GLY A 1 26  ? -18.035 -33.392 4.825    1.00 65.17  ? 26  GLY A CA    1 
ATOM   169   C  C     . GLY A 1 26  ? -17.901 -33.718 3.339    1.00 71.02  ? 26  GLY A C     1 
ATOM   170   O  O     . GLY A 1 26  ? -18.409 -32.995 2.476    1.00 60.58  ? 26  GLY A O     1 
ATOM   171   N  N     . ALA A 1 27  ? -17.253 -34.859 3.068    1.00 72.04  ? 27  ALA A N     1 
ATOM   172   C  CA    . ALA A 1 27  ? -16.898 -35.274 1.720    1.00 66.99  ? 27  ALA A CA    1 
ATOM   173   C  C     . ALA A 1 27  ? -18.138 -35.541 0.871    1.00 58.24  ? 27  ALA A C     1 
ATOM   174   O  O     . ALA A 1 27  ? -18.079 -35.418 -0.353   1.00 71.13  ? 27  ALA A O     1 
ATOM   175   C  CB    . ALA A 1 27  ? -16.000 -36.488 1.781    1.00 67.81  ? 27  ALA A CB    1 
ATOM   176   N  N     . ASP A 1 28  ? -19.273 -35.873 1.495    1.00 59.37  ? 28  ASP A N     1 
ATOM   177   C  CA    . ASP A 1 28  ? -20.505 -36.105 0.746    1.00 65.03  ? 28  ASP A CA    1 
ATOM   178   C  C     . ASP A 1 28  ? -21.031 -34.848 0.029    1.00 66.13  ? 28  ASP A C     1 
ATOM   179   O  O     . ASP A 1 28  ? -21.807 -34.969 -0.927   1.00 55.49  ? 28  ASP A O     1 
ATOM   180   C  CB    . ASP A 1 28  ? -21.600 -36.664 1.649    1.00 73.73  ? 28  ASP A CB    1 
ATOM   181   C  CG    . ASP A 1 28  ? -21.378 -38.125 1.994    1.00 76.86  ? 28  ASP A CG    1 
ATOM   182   O  OD1   . ASP A 1 28  ? -20.358 -38.422 2.639    1.00 70.46  ? 28  ASP A OD1   1 
ATOM   183   O  OD2   . ASP A 1 28  ? -22.221 -38.949 1.600    1.00 75.94  ? 28  ASP A OD2   1 
ATOM   184   N  N     . TRP A 1 29  ? -20.612 -33.648 0.465    1.00 59.88  ? 29  TRP A N     1 
ATOM   185   C  CA    . TRP A 1 29  ? -21.274 -32.414 0.055    1.00 61.47  ? 29  TRP A CA    1 
ATOM   186   C  C     . TRP A 1 29  ? -20.348 -31.546 -0.793   1.00 64.34  ? 29  TRP A C     1 
ATOM   187   O  O     . TRP A 1 29  ? -20.513 -30.330 -0.871   1.00 59.21  ? 29  TRP A O     1 
ATOM   188   C  CB    . TRP A 1 29  ? -21.781 -31.688 1.307    1.00 58.50  ? 29  TRP A CB    1 
ATOM   189   C  CG    . TRP A 1 29  ? -22.766 -32.515 2.070    1.00 51.54  ? 29  TRP A CG    1 
ATOM   190   C  CD1   . TRP A 1 29  ? -22.615 -33.045 3.325    1.00 54.08  ? 29  TRP A CD1   1 
ATOM   191   C  CD2   . TRP A 1 29  ? -24.047 -32.958 1.589    1.00 45.02  ? 29  TRP A CD2   1 
ATOM   192   N  NE1   . TRP A 1 29  ? -23.738 -33.752 3.675    1.00 56.69  ? 29  TRP A NE1   1 
ATOM   193   C  CE2   . TRP A 1 29  ? -24.625 -33.725 2.624    1.00 52.09  ? 29  TRP A CE2   1 
ATOM   194   C  CE3   . TRP A 1 29  ? -24.763 -32.766 0.399    1.00 44.93  ? 29  TRP A CE3   1 
ATOM   195   C  CZ2   . TRP A 1 29  ? -25.879 -34.312 2.490    1.00 46.28  ? 29  TRP A CZ2   1 
ATOM   196   C  CZ3   . TRP A 1 29  ? -26.006 -33.340 0.271    1.00 48.48  ? 29  TRP A CZ3   1 
ATOM   197   C  CH2   . TRP A 1 29  ? -26.550 -34.106 1.306    1.00 48.01  ? 29  TRP A CH2   1 
ATOM   198   N  N     . VAL A 1 30  ? -19.359 -32.199 -1.407   1.00 66.86  ? 30  VAL A N     1 
ATOM   199   C  CA    . VAL A 1 30  ? -18.541 -31.600 -2.437   1.00 62.51  ? 30  VAL A CA    1 
ATOM   200   C  C     . VAL A 1 30  ? -18.772 -32.412 -3.702   1.00 69.09  ? 30  VAL A C     1 
ATOM   201   O  O     . VAL A 1 30  ? -18.536 -33.613 -3.706   1.00 76.56  ? 30  VAL A O     1 
ATOM   202   C  CB    . VAL A 1 30  ? -17.058 -31.571 -2.031   1.00 64.66  ? 30  VAL A CB    1 
ATOM   203   C  CG1   . VAL A 1 30  ? -16.201 -31.044 -3.167   1.00 67.71  ? 30  VAL A CG1   1 
ATOM   204   C  CG2   . VAL A 1 30  ? -16.830 -30.753 -0.772   1.00 60.81  ? 30  VAL A CG2   1 
ATOM   205   N  N     . PHE A 1 31  ? -19.261 -31.753 -4.754   1.00 66.82  ? 31  PHE A N     1 
ATOM   206   C  CA    . PHE A 1 31  ? -19.650 -32.417 -5.983   1.00 70.39  ? 31  PHE A CA    1 
ATOM   207   C  C     . PHE A 1 31  ? -18.688 -32.032 -7.106   1.00 73.15  ? 31  PHE A C     1 
ATOM   208   O  O     . PHE A 1 31  ? -18.218 -30.896 -7.144   1.00 66.89  ? 31  PHE A O     1 
ATOM   209   C  CB    . PHE A 1 31  ? -21.091 -32.042 -6.331   1.00 68.44  ? 31  PHE A CB    1 
ATOM   210   C  CG    . PHE A 1 31  ? -22.078 -32.381 -5.246   1.00 77.69  ? 31  PHE A CG    1 
ATOM   211   C  CD1   . PHE A 1 31  ? -22.517 -33.685 -5.069   1.00 75.22  ? 31  PHE A CD1   1 
ATOM   212   C  CD2   . PHE A 1 31  ? -22.525 -31.409 -4.370   1.00 77.11  ? 31  PHE A CD2   1 
ATOM   213   C  CE1   . PHE A 1 31  ? -23.418 -33.997 -4.067   1.00 66.26  ? 31  PHE A CE1   1 
ATOM   214   C  CE2   . PHE A 1 31  ? -23.421 -31.728 -3.365   1.00 73.37  ? 31  PHE A CE2   1 
ATOM   215   C  CZ    . PHE A 1 31  ? -23.869 -33.019 -3.221   1.00 68.29  ? 31  PHE A CZ    1 
ATOM   216   N  N     . THR A 1 32  ? -18.424 -32.991 -8.013   1.00 71.08  ? 32  THR A N     1 
ATOM   217   C  CA    . THR A 1 32  ? -17.531 -32.803 -9.153   1.00 74.58  ? 32  THR A CA    1 
ATOM   218   C  C     . THR A 1 32  ? -18.020 -33.632 -10.346  1.00 75.82  ? 32  THR A C     1 
ATOM   219   O  O     . THR A 1 32  ? -18.965 -34.406 -10.208  1.00 76.39  ? 32  THR A O     1 
ATOM   220   C  CB    . THR A 1 32  ? -16.077 -33.138 -8.788   1.00 65.89  ? 32  THR A CB    1 
ATOM   221   O  OG1   . THR A 1 32  ? -16.032 -34.424 -8.180   1.00 65.48  ? 32  THR A OG1   1 
ATOM   222   C  CG2   . THR A 1 32  ? -15.461 -32.147 -7.826   1.00 68.73  ? 32  THR A CG2   1 
ATOM   223   N  N     . GLU A 1 33  ? -17.412 -33.386 -11.522  1.00 87.98  ? 33  GLU A N     1 
ATOM   224   C  CA    . GLU A 1 33  ? -17.512 -34.218 -12.721  1.00 99.05  ? 33  GLU A CA    1 
ATOM   225   C  C     . GLU A 1 33  ? -18.963 -34.428 -13.183  1.00 103.22 ? 33  GLU A C     1 
ATOM   226   O  O     . GLU A 1 33  ? -19.540 -33.552 -13.828  1.00 102.80 ? 33  GLU A O     1 
ATOM   227   C  CB    . GLU A 1 33  ? -16.778 -35.537 -12.472  1.00 99.85  ? 33  GLU A CB    1 
ATOM   228   C  CG    . GLU A 1 33  ? -15.305 -35.354 -12.150  1.00 100.57 ? 33  GLU A CG    1 
ATOM   229   C  CD    . GLU A 1 33  ? -14.741 -36.414 -11.222  1.00 104.24 ? 33  GLU A CD    1 
ATOM   230   O  OE1   . GLU A 1 33  ? -15.484 -37.357 -10.883  1.00 97.01  ? 33  GLU A OE1   1 
ATOM   231   O  OE2   . GLU A 1 33  ? -13.568 -36.280 -10.818  1.00 107.35 ? 33  GLU A OE2   1 
ATOM   232   N  N     . ASP A 1 34  ? -19.527 -35.615 -12.898  1.00 103.19 ? 34  ASP A N     1 
ATOM   233   C  CA    . ASP A 1 34  ? -20.840 -36.019 -13.382  1.00 107.84 ? 34  ASP A CA    1 
ATOM   234   C  C     . ASP A 1 34  ? -21.949 -35.343 -12.582  1.00 100.54 ? 34  ASP A C     1 
ATOM   235   O  O     . ASP A 1 34  ? -23.016 -35.053 -13.118  1.00 89.57  ? 34  ASP A O     1 
ATOM   236   C  CB    . ASP A 1 34  ? -21.043 -37.532 -13.258  1.00 119.62 ? 34  ASP A CB    1 
ATOM   237   C  CG    . ASP A 1 34  ? -20.219 -38.362 -14.227  1.00 126.95 ? 34  ASP A CG    1 
ATOM   238   O  OD1   . ASP A 1 34  ? -19.619 -37.768 -15.149  1.00 129.16 ? 34  ASP A OD1   1 
ATOM   239   O  OD2   . ASP A 1 34  ? -20.181 -39.598 -14.043  1.00 126.86 ? 34  ASP A OD2   1 
ATOM   240   N  N     . LYS A 1 35  ? -21.685 -35.109 -11.292  1.00 95.07  ? 35  LYS A N     1 
ATOM   241   C  CA    . LYS A 1 35  ? -22.684 -34.588 -10.376  1.00 91.54  ? 35  LYS A CA    1 
ATOM   242   C  C     . LYS A 1 35  ? -22.818 -33.071 -10.508  1.00 86.44  ? 35  LYS A C     1 
ATOM   243   O  O     . LYS A 1 35  ? -23.627 -32.474 -9.802   1.00 82.01  ? 35  LYS A O     1 
ATOM   244   C  CB    . LYS A 1 35  ? -22.306 -35.038 -8.964   1.00 90.47  ? 35  LYS A CB    1 
ATOM   245   C  CG    . LYS A 1 35  ? -22.234 -36.552 -8.814   1.00 94.87  ? 35  LYS A CG    1 
ATOM   246   C  CD    . LYS A 1 35  ? -22.103 -37.032 -7.395   1.00 100.65 ? 35  LYS A CD    1 
ATOM   247   C  CE    . LYS A 1 35  ? -22.612 -38.447 -7.214   1.00 101.88 ? 35  LYS A CE    1 
ATOM   248   N  NZ    . LYS A 1 35  ? -22.684 -38.821 -5.782   1.00 106.32 ? 35  LYS A NZ    1 
ATOM   249   N  N     . ILE A 1 36  ? -22.058 -32.464 -11.435  1.00 87.42  ? 36  ILE A N     1 
ATOM   250   C  CA    . ILE A 1 36  ? -22.034 -31.019 -11.617  1.00 86.16  ? 36  ILE A CA    1 
ATOM   251   C  C     . ILE A 1 36  ? -23.011 -30.606 -12.720  1.00 79.23  ? 36  ILE A C     1 
ATOM   252   O  O     . ILE A 1 36  ? -23.245 -29.416 -12.907  1.00 79.71  ? 36  ILE A O     1 
ATOM   253   C  CB    . ILE A 1 36  ? -20.600 -30.521 -11.917  1.00 82.58  ? 36  ILE A CB    1 
ATOM   254   C  CG1   . ILE A 1 36  ? -20.324 -29.149 -11.297  1.00 80.03  ? 36  ILE A CG1   1 
ATOM   255   C  CG2   . ILE A 1 36  ? -20.308 -30.525 -13.414  1.00 84.92  ? 36  ILE A CG2   1 
ATOM   256   C  CD1   . ILE A 1 36  ? -20.481 -29.115 -9.799   1.00 85.87  ? 36  ILE A CD1   1 
ATOM   257   N  N     . THR A 1 37  ? -23.584 -31.574 -13.449  1.00 78.94  ? 37  THR A N     1 
ATOM   258   C  CA    . THR A 1 37  ? -24.434 -31.248 -14.588  1.00 80.24  ? 37  THR A CA    1 
ATOM   259   C  C     . THR A 1 37  ? -25.752 -30.599 -14.140  1.00 76.38  ? 37  THR A C     1 
ATOM   260   O  O     . THR A 1 37  ? -26.259 -29.741 -14.863  1.00 68.23  ? 37  THR A O     1 
ATOM   261   C  CB    . THR A 1 37  ? -24.681 -32.460 -15.501  1.00 77.02  ? 37  THR A CB    1 
ATOM   262   O  OG1   . THR A 1 37  ? -25.491 -33.383 -14.771  1.00 69.73  ? 37  THR A OG1   1 
ATOM   263   C  CG2   . THR A 1 37  ? -23.403 -33.111 -15.987  1.00 70.70  ? 37  THR A CG2   1 
ATOM   264   N  N     . PRO A 1 38  ? -26.371 -30.957 -12.979  1.00 76.51  ? 38  PRO A N     1 
ATOM   265   C  CA    . PRO A 1 38  ? -27.542 -30.220 -12.482  1.00 69.92  ? 38  PRO A CA    1 
ATOM   266   C  C     . PRO A 1 38  ? -27.330 -28.707 -12.361  1.00 62.97  ? 38  PRO A C     1 
ATOM   267   O  O     . PRO A 1 38  ? -28.297 -27.947 -12.375  1.00 58.09  ? 38  PRO A O     1 
ATOM   268   C  CB    . PRO A 1 38  ? -27.813 -30.819 -11.088  1.00 73.59  ? 38  PRO A CB    1 
ATOM   269   C  CG    . PRO A 1 38  ? -27.187 -32.204 -11.137  1.00 77.40  ? 38  PRO A CG    1 
ATOM   270   C  CD    . PRO A 1 38  ? -26.019 -32.087 -12.097  1.00 76.65  ? 38  PRO A CD    1 
ATOM   271   N  N     . TYR A 1 39  ? -26.062 -28.281 -12.264  1.00 61.90  ? 39  TYR A N     1 
ATOM   272   C  CA    . TYR A 1 39  ? -25.699 -26.883 -12.072  1.00 66.38  ? 39  TYR A CA    1 
ATOM   273   C  C     . TYR A 1 39  ? -25.396 -26.175 -13.400  1.00 68.04  ? 39  TYR A C     1 
ATOM   274   O  O     . TYR A 1 39  ? -25.150 -24.970 -13.396  1.00 58.29  ? 39  TYR A O     1 
ATOM   275   C  CB    . TYR A 1 39  ? -24.501 -26.789 -11.119  1.00 67.17  ? 39  TYR A CB    1 
ATOM   276   C  CG    . TYR A 1 39  ? -24.741 -27.321 -9.724   1.00 68.35  ? 39  TYR A CG    1 
ATOM   277   C  CD1   . TYR A 1 39  ? -25.434 -26.570 -8.785   1.00 63.71  ? 39  TYR A CD1   1 
ATOM   278   C  CD2   . TYR A 1 39  ? -24.288 -28.576 -9.334   1.00 59.89  ? 39  TYR A CD2   1 
ATOM   279   C  CE1   . TYR A 1 39  ? -25.663 -27.044 -7.501   1.00 62.16  ? 39  TYR A CE1   1 
ATOM   280   C  CE2   . TYR A 1 39  ? -24.511 -29.064 -8.051   1.00 66.69  ? 39  TYR A CE2   1 
ATOM   281   C  CZ    . TYR A 1 39  ? -25.191 -28.289 -7.123   1.00 66.04  ? 39  TYR A CZ    1 
ATOM   282   O  OH    . TYR A 1 39  ? -25.415 -28.720 -5.835   1.00 61.40  ? 39  TYR A OH    1 
ATOM   283   N  N     . GLU A 1 40  ? -25.421 -26.901 -14.537  1.00 65.94  ? 40  GLU A N     1 
ATOM   284   C  CA    . GLU A 1 40  ? -25.331 -26.282 -15.857  1.00 56.09  ? 40  GLU A CA    1 
ATOM   285   C  C     . GLU A 1 40  ? -26.609 -25.476 -16.110  1.00 60.26  ? 40  GLU A C     1 
ATOM   286   O  O     . GLU A 1 40  ? -27.664 -25.783 -15.549  1.00 55.85  ? 40  GLU A O     1 
ATOM   287   C  CB    . GLU A 1 40  ? -25.189 -27.328 -16.972  1.00 56.28  ? 40  GLU A CB    1 
ATOM   288   C  CG    . GLU A 1 40  ? -24.005 -28.267 -16.809  1.00 60.81  ? 40  GLU A CG    1 
ATOM   289   C  CD    . GLU A 1 40  ? -22.645 -27.598 -16.882  1.00 64.61  ? 40  GLU A CD    1 
ATOM   290   O  OE1   . GLU A 1 40  ? -22.574 -26.435 -17.346  1.00 68.67  ? 40  GLU A OE1   1 
ATOM   291   O  OE2   . GLU A 1 40  ? -21.660 -28.230 -16.451  1.00 70.49  ? 40  GLU A OE2   1 
ATOM   292   N  N     . ASP A 1 41  ? -26.523 -24.445 -16.962  1.00 55.00  ? 41  ASP A N     1 
ATOM   293   C  CA    . ASP A 1 41  ? -27.722 -23.755 -17.413  1.00 56.45  ? 41  ASP A CA    1 
ATOM   294   C  C     . ASP A 1 41  ? -28.600 -24.774 -18.131  1.00 56.59  ? 41  ASP A C     1 
ATOM   295   O  O     . ASP A 1 41  ? -28.136 -25.361 -19.109  1.00 57.23  ? 41  ASP A O     1 
ATOM   296   C  CB    . ASP A 1 41  ? -27.411 -22.590 -18.360  1.00 54.04  ? 41  ASP A CB    1 
ATOM   297   C  CG    . ASP A 1 41  ? -28.619 -21.736 -18.745  1.00 59.15  ? 41  ASP A CG    1 
ATOM   298   O  OD1   . ASP A 1 41  ? -29.763 -22.028 -18.270  1.00 54.73  ? 41  ASP A OD1   1 
ATOM   299   O  OD2   . ASP A 1 41  ? -28.415 -20.759 -19.517  1.00 59.42  ? 41  ASP A OD2   1 
ATOM   300   N  N     . PRO A 1 42  ? -29.866 -25.011 -17.686  1.00 62.43  ? 42  PRO A N     1 
ATOM   301   C  CA    . PRO A 1 42  ? -30.794 -25.872 -18.426  1.00 58.79  ? 42  PRO A CA    1 
ATOM   302   C  C     . PRO A 1 42  ? -31.207 -25.340 -19.802  1.00 62.76  ? 42  PRO A C     1 
ATOM   303   O  O     . PRO A 1 42  ? -31.616 -26.133 -20.653  1.00 59.71  ? 42  PRO A O     1 
ATOM   304   C  CB    . PRO A 1 42  ? -32.021 -25.943 -17.501  1.00 63.20  ? 42  PRO A CB    1 
ATOM   305   C  CG    . PRO A 1 42  ? -31.967 -24.633 -16.739  1.00 69.86  ? 42  PRO A CG    1 
ATOM   306   C  CD    . PRO A 1 42  ? -30.486 -24.454 -16.467  1.00 64.93  ? 42  PRO A CD    1 
ATOM   307   N  N     . TYR A 1 43  ? -31.154 -24.003 -19.992  1.00 60.41  ? 43  TYR A N     1 
ATOM   308   C  CA    . TYR A 1 43  ? -31.514 -23.363 -21.256  1.00 63.59  ? 43  TYR A CA    1 
ATOM   309   C  C     . TYR A 1 43  ? -30.255 -22.784 -21.912  1.00 65.23  ? 43  TYR A C     1 
ATOM   310   O  O     . TYR A 1 43  ? -30.094 -21.563 -21.967  1.00 66.32  ? 43  TYR A O     1 
ATOM   311   C  CB    . TYR A 1 43  ? -32.599 -22.293 -21.053  1.00 58.28  ? 43  TYR A CB    1 
ATOM   312   C  CG    . TYR A 1 43  ? -33.806 -22.731 -20.256  1.00 58.40  ? 43  TYR A CG    1 
ATOM   313   C  CD1   . TYR A 1 43  ? -34.206 -24.065 -20.177  1.00 56.33  ? 43  TYR A CD1   1 
ATOM   314   C  CD2   . TYR A 1 43  ? -34.531 -21.801 -19.526  1.00 56.90  ? 43  TYR A CD2   1 
ATOM   315   C  CE1   . TYR A 1 43  ? -35.314 -24.449 -19.429  1.00 58.86  ? 43  TYR A CE1   1 
ATOM   316   C  CE2   . TYR A 1 43  ? -35.637 -22.167 -18.772  1.00 57.36  ? 43  TYR A CE2   1 
ATOM   317   C  CZ    . TYR A 1 43  ? -36.028 -23.496 -18.715  1.00 57.60  ? 43  TYR A CZ    1 
ATOM   318   O  OH    . TYR A 1 43  ? -37.109 -23.824 -17.938  1.00 57.23  ? 43  TYR A OH    1 
ATOM   319   N  N     . THR A 1 44  ? -29.380 -23.693 -22.388  1.00 60.94  ? 44  THR A N     1 
ATOM   320   C  CA    . THR A 1 44  ? -28.151 -23.390 -23.116  1.00 57.01  ? 44  THR A CA    1 
ATOM   321   C  C     . THR A 1 44  ? -28.417 -22.301 -24.149  1.00 56.14  ? 44  THR A C     1 
ATOM   322   O  O     . THR A 1 44  ? -29.336 -22.427 -24.957  1.00 57.92  ? 44  THR A O     1 
ATOM   323   C  CB    . THR A 1 44  ? -27.596 -24.635 -23.838  1.00 56.16  ? 44  THR A CB    1 
ATOM   324   O  OG1   . THR A 1 44  ? -27.827 -25.753 -22.985  1.00 57.69  ? 44  THR A OG1   1 
ATOM   325   C  CG2   . THR A 1 44  ? -26.120 -24.561 -24.192  1.00 51.56  ? 44  THR A CG2   1 
ATOM   326   N  N     . ILE A 1 45  ? -27.626 -21.224 -24.083  1.00 59.06  ? 45  ILE A N     1 
ATOM   327   C  CA    . ILE A 1 45  ? -27.662 -20.170 -25.084  1.00 61.32  ? 45  ILE A CA    1 
ATOM   328   C  C     . ILE A 1 45  ? -26.369 -20.244 -25.889  1.00 61.58  ? 45  ILE A C     1 
ATOM   329   O  O     . ILE A 1 45  ? -26.421 -20.329 -27.107  1.00 56.45  ? 45  ILE A O     1 
ATOM   330   C  CB    . ILE A 1 45  ? -27.906 -18.775 -24.466  1.00 56.65  ? 45  ILE A CB    1 
ATOM   331   C  CG1   . ILE A 1 45  ? -29.192 -18.758 -23.626  1.00 54.42  ? 45  ILE A CG1   1 
ATOM   332   C  CG2   . ILE A 1 45  ? -27.912 -17.711 -25.566  1.00 60.41  ? 45  ILE A CG2   1 
ATOM   333   C  CD1   . ILE A 1 45  ? -29.682 -17.383 -23.218  1.00 51.33  ? 45  ILE A CD1   1 
ATOM   334   N  N     . SER A 1 46  ? -25.230 -20.252 -25.192  1.00 62.25  ? 46  SER A N     1 
ATOM   335   C  CA    . SER A 1 46  ? -23.928 -20.336 -25.827  1.00 64.91  ? 46  SER A CA    1 
ATOM   336   C  C     . SER A 1 46  ? -23.767 -21.623 -26.632  1.00 69.26  ? 46  SER A C     1 
ATOM   337   O  O     . SER A 1 46  ? -24.274 -22.682 -26.240  1.00 67.59  ? 46  SER A O     1 
ATOM   338   C  CB    . SER A 1 46  ? -22.832 -20.248 -24.812  1.00 69.62  ? 46  SER A CB    1 
ATOM   339   O  OG    . SER A 1 46  ? -21.579 -20.227 -25.473  1.00 69.18  ? 46  SER A OG    1 
ATOM   340   N  N     . ASN A 1 47  ? -23.003 -21.492 -27.731  1.00 64.21  ? 47  ASN A N     1 
ATOM   341   C  CA    . ASN A 1 47  ? -22.562 -22.608 -28.550  1.00 67.11  ? 47  ASN A CA    1 
ATOM   342   C  C     . ASN A 1 47  ? -21.112 -22.982 -28.232  1.00 69.77  ? 47  ASN A C     1 
ATOM   343   O  O     . ASN A 1 47  ? -20.595 -23.943 -28.800  1.00 67.26  ? 47  ASN A O     1 
ATOM   344   C  CB    . ASN A 1 47  ? -22.778 -22.315 -30.037  1.00 60.59  ? 47  ASN A CB    1 
ATOM   345   C  CG    . ASN A 1 47  ? -24.222 -22.527 -30.440  1.00 57.55  ? 47  ASN A CG    1 
ATOM   346   O  OD1   . ASN A 1 47  ? -24.934 -23.289 -29.797  1.00 61.06  ? 47  ASN A OD1   1 
ATOM   347   N  ND2   . ASN A 1 47  ? -24.670 -21.871 -31.495  1.00 55.26  ? 47  ASN A ND2   1 
ATOM   348   N  N     . ASP A 1 48  ? -20.475 -22.257 -27.305  1.00 64.87  ? 48  ASP A N     1 
ATOM   349   C  CA    . ASP A 1 48  ? -19.109 -22.548 -26.895  1.00 64.64  ? 48  ASP A CA    1 
ATOM   350   C  C     . ASP A 1 48  ? -19.133 -23.182 -25.503  1.00 62.74  ? 48  ASP A C     1 
ATOM   351   O  O     . ASP A 1 48  ? -19.413 -22.511 -24.517  1.00 68.00  ? 48  ASP A O     1 
ATOM   352   C  CB    . ASP A 1 48  ? -18.262 -21.272 -26.967  1.00 71.70  ? 48  ASP A CB    1 
ATOM   353   C  CG    . ASP A 1 48  ? -16.875 -21.370 -26.344  1.00 68.38  ? 48  ASP A CG    1 
ATOM   354   O  OD1   . ASP A 1 48  ? -16.536 -22.437 -25.795  1.00 72.98  ? 48  ASP A OD1   1 
ATOM   355   O  OD2   . ASP A 1 48  ? -16.151 -20.367 -26.404  1.00 65.70  ? 48  ASP A OD2   1 
ATOM   356   N  N     . GLU A 1 49  ? -18.796 -24.473 -25.427  1.00 61.04  ? 49  GLU A N     1 
ATOM   357   C  CA    . GLU A 1 49  ? -18.999 -25.275 -24.229  1.00 67.63  ? 49  GLU A CA    1 
ATOM   358   C  C     . GLU A 1 49  ? -17.948 -24.994 -23.152  1.00 63.24  ? 49  GLU A C     1 
ATOM   359   O  O     . GLU A 1 49  ? -18.009 -25.597 -22.089  1.00 58.77  ? 49  GLU A O     1 
ATOM   360   C  CB    . GLU A 1 49  ? -19.034 -26.759 -24.601  1.00 74.43  ? 49  GLU A CB    1 
ATOM   361   C  CG    . GLU A 1 49  ? -20.394 -27.205 -25.106  1.00 80.19  ? 49  GLU A CG    1 
ATOM   362   C  CD    . GLU A 1 49  ? -20.424 -28.631 -25.618  1.00 88.89  ? 49  GLU A CD    1 
ATOM   363   O  OE1   . GLU A 1 49  ? -21.055 -29.479 -24.960  1.00 102.63 ? 49  GLU A OE1   1 
ATOM   364   O  OE2   . GLU A 1 49  ? -19.814 -28.886 -26.670  1.00 88.75  ? 49  GLU A OE2   1 
ATOM   365   N  N     . THR A 1 50  ? -17.021 -24.057 -23.403  1.00 68.19  ? 50  THR A N     1 
ATOM   366   C  CA    . THR A 1 50  ? -16.108 -23.566 -22.380  1.00 61.20  ? 50  THR A CA    1 
ATOM   367   C  C     . THR A 1 50  ? -16.732 -22.423 -21.561  1.00 65.02  ? 50  THR A C     1 
ATOM   368   O  O     . THR A 1 50  ? -16.087 -21.954 -20.626  1.00 66.59  ? 50  THR A O     1 
ATOM   369   C  CB    . THR A 1 50  ? -14.764 -23.126 -22.994  1.00 64.79  ? 50  THR A CB    1 
ATOM   370   O  OG1   . THR A 1 50  ? -14.935 -21.999 -23.855  1.00 64.49  ? 50  THR A OG1   1 
ATOM   371   C  CG2   . THR A 1 50  ? -14.092 -24.213 -23.805  1.00 65.55  ? 50  THR A CG2   1 
ATOM   372   N  N     . GLU A 1 51  ? -17.968 -21.981 -21.883  1.00 66.35  ? 51  GLU A N     1 
ATOM   373   C  CA    . GLU A 1 51  ? -18.575 -20.793 -21.274  1.00 67.72  ? 51  GLU A CA    1 
ATOM   374   C  C     . GLU A 1 51  ? -19.617 -21.164 -20.208  1.00 64.11  ? 51  GLU A C     1 
ATOM   375   O  O     . GLU A 1 51  ? -20.389 -22.108 -20.390  1.00 57.15  ? 51  GLU A O     1 
ATOM   376   C  CB    . GLU A 1 51  ? -19.251 -19.908 -22.332  1.00 65.76  ? 51  GLU A CB    1 
ATOM   377   C  CG    . GLU A 1 51  ? -18.287 -19.223 -23.288  1.00 71.41  ? 51  GLU A CG    1 
ATOM   378   C  CD    . GLU A 1 51  ? -18.915 -18.188 -24.210  1.00 77.61  ? 51  GLU A CD    1 
ATOM   379   O  OE1   . GLU A 1 51  ? -19.830 -18.541 -24.981  1.00 76.10  ? 51  GLU A OE1   1 
ATOM   380   O  OE2   . GLU A 1 51  ? -18.481 -17.022 -24.166  1.00 85.93  ? 51  GLU A OE2   1 
ATOM   381   N  N     . HIS A 1 52  ? -19.656 -20.385 -19.109  1.00 59.00  ? 52  HIS A N     1 
ATOM   382   C  CA    . HIS A 1 52  ? -20.590 -20.594 -18.003  1.00 60.35  ? 52  HIS A CA    1 
ATOM   383   C  C     . HIS A 1 52  ? -20.560 -22.025 -17.444  1.00 63.55  ? 52  HIS A C     1 
ATOM   384   O  O     . HIS A 1 52  ? -21.624 -22.562 -17.112  1.00 61.67  ? 52  HIS A O     1 
ATOM   385   C  CB    . HIS A 1 52  ? -22.034 -20.292 -18.428  1.00 56.40  ? 52  HIS A CB    1 
ATOM   386   C  CG    . HIS A 1 52  ? -22.133 -19.146 -19.352  1.00 61.72  ? 52  HIS A CG    1 
ATOM   387   N  ND1   . HIS A 1 52  ? -21.329 -18.035 -19.225  1.00 66.18  ? 52  HIS A ND1   1 
ATOM   388   C  CD2   . HIS A 1 52  ? -22.879 -18.963 -20.448  1.00 65.11  ? 52  HIS A CD2   1 
ATOM   389   C  CE1   . HIS A 1 52  ? -21.632 -17.182 -20.197  1.00 71.59  ? 52  HIS A CE1   1 
ATOM   390   N  NE2   . HIS A 1 52  ? -22.568 -17.728 -20.957  1.00 70.35  ? 52  HIS A NE2   1 
ATOM   391   N  N     . ARG A 1 53  ? -19.351 -22.615 -17.303  1.00 61.24  ? 53  ARG A N     1 
ATOM   392   C  CA    . ARG A 1 53  ? -19.162 -23.972 -16.792  1.00 63.65  ? 53  ARG A CA    1 
ATOM   393   C  C     . ARG A 1 53  ? -18.711 -23.948 -15.327  1.00 64.75  ? 53  ARG A C     1 
ATOM   394   O  O     . ARG A 1 53  ? -17.649 -23.432 -14.992  1.00 71.58  ? 53  ARG A O     1 
ATOM   395   C  CB    . ARG A 1 53  ? -18.128 -24.739 -17.626  1.00 62.58  ? 53  ARG A CB    1 
ATOM   396   C  CG    . ARG A 1 53  ? -18.339 -24.637 -19.133  1.00 67.41  ? 53  ARG A CG    1 
ATOM   397   C  CD    . ARG A 1 53  ? -19.746 -25.007 -19.580  1.00 67.41  ? 53  ARG A CD    1 
ATOM   398   N  NE    . ARG A 1 53  ? -20.079 -26.370 -19.185  1.00 73.91  ? 53  ARG A NE    1 
ATOM   399   C  CZ    . ARG A 1 53  ? -19.486 -27.473 -19.648  1.00 73.12  ? 53  ARG A CZ    1 
ATOM   400   N  NH1   . ARG A 1 53  ? -18.623 -27.409 -20.650  1.00 73.18  ? 53  ARG A NH1   1 
ATOM   401   N  NH2   . ARG A 1 53  ? -19.778 -28.648 -19.115  1.00 66.23  ? 53  ARG A NH2   1 
ATOM   402   N  N     . PRO A 1 54  ? -19.496 -24.517 -14.387  1.00 62.50  ? 54  PRO A N     1 
ATOM   403   C  CA    . PRO A 1 54  ? -19.032 -24.661 -13.007  1.00 61.44  ? 54  PRO A CA    1 
ATOM   404   C  C     . PRO A 1 54  ? -18.018 -25.783 -12.840  1.00 57.57  ? 54  PRO A C     1 
ATOM   405   O  O     . PRO A 1 54  ? -18.195 -26.863 -13.388  1.00 61.79  ? 54  PRO A O     1 
ATOM   406   C  CB    . PRO A 1 54  ? -20.309 -24.945 -12.213  1.00 59.52  ? 54  PRO A CB    1 
ATOM   407   C  CG    . PRO A 1 54  ? -21.302 -25.482 -13.227  1.00 59.26  ? 54  PRO A CG    1 
ATOM   408   C  CD    . PRO A 1 54  ? -20.881 -24.962 -14.584  1.00 61.09  ? 54  PRO A CD    1 
ATOM   409   N  N     . TYR A 1 55  ? -16.980 -25.520 -12.045  1.00 50.62  ? 55  TYR A N     1 
ATOM   410   C  CA    . TYR A 1 55  ? -15.927 -26.488 -11.813  1.00 57.26  ? 55  TYR A CA    1 
ATOM   411   C  C     . TYR A 1 55  ? -16.276 -27.533 -10.752  1.00 66.01  ? 55  TYR A C     1 
ATOM   412   O  O     . TYR A 1 55  ? -15.691 -28.609 -10.732  1.00 68.19  ? 55  TYR A O     1 
ATOM   413   C  CB    . TYR A 1 55  ? -14.669 -25.794 -11.307  1.00 58.69  ? 55  TYR A CB    1 
ATOM   414   C  CG    . TYR A 1 55  ? -13.480 -26.708 -11.354  1.00 68.47  ? 55  TYR A CG    1 
ATOM   415   C  CD1   . TYR A 1 55  ? -12.770 -26.868 -12.531  1.00 76.74  ? 55  TYR A CD1   1 
ATOM   416   C  CD2   . TYR A 1 55  ? -13.132 -27.487 -10.263  1.00 71.54  ? 55  TYR A CD2   1 
ATOM   417   C  CE1   . TYR A 1 55  ? -11.689 -27.727 -12.601  1.00 80.33  ? 55  TYR A CE1   1 
ATOM   418   C  CE2   . TYR A 1 55  ? -12.051 -28.348 -10.316  1.00 74.46  ? 55  TYR A CE2   1 
ATOM   419   C  CZ    . TYR A 1 55  ? -11.328 -28.461 -11.489  1.00 73.75  ? 55  TYR A CZ    1 
ATOM   420   O  OH    . TYR A 1 55  ? -10.267 -29.310 -11.573  1.00 80.24  ? 55  TYR A OH    1 
ATOM   421   N  N     . ALA A 1 56  ? -17.136 -27.165 -9.803   1.00 66.05  ? 56  ALA A N     1 
ATOM   422   C  CA    . ALA A 1 56  ? -17.428 -27.977 -8.633   1.00 62.75  ? 56  ALA A CA    1 
ATOM   423   C  C     . ALA A 1 56  ? -18.525 -27.266 -7.849   1.00 62.99  ? 56  ALA A C     1 
ATOM   424   O  O     . ALA A 1 56  ? -18.889 -26.143 -8.188   1.00 57.79  ? 56  ALA A O     1 
ATOM   425   C  CB    . ALA A 1 56  ? -16.186 -28.186 -7.800   1.00 58.37  ? 56  ALA A CB    1 
ATOM   426   N  N     . ALA A 1 57  ? -19.085 -27.943 -6.848   1.00 62.76  ? 57  ALA A N     1 
ATOM   427   C  CA    . ALA A 1 57  ? -20.163 -27.382 -6.049   1.00 55.32  ? 57  ALA A CA    1 
ATOM   428   C  C     . ALA A 1 57  ? -20.008 -27.889 -4.627   1.00 60.61  ? 57  ALA A C     1 
ATOM   429   O  O     . ALA A 1 57  ? -19.583 -29.028 -4.430   1.00 67.46  ? 57  ALA A O     1 
ATOM   430   C  CB    . ALA A 1 57  ? -21.511 -27.752 -6.618   1.00 55.68  ? 57  ALA A CB    1 
ATOM   431   N  N     . VAL A 1 58  ? -20.316 -27.024 -3.651   1.00 57.99  ? 58  VAL A N     1 
ATOM   432   C  CA    . VAL A 1 58  ? -20.156 -27.370 -2.249   1.00 51.25  ? 58  VAL A CA    1 
ATOM   433   C  C     . VAL A 1 58  ? -21.391 -26.899 -1.495   1.00 51.81  ? 58  VAL A C     1 
ATOM   434   O  O     . VAL A 1 58  ? -21.896 -25.801 -1.737   1.00 54.55  ? 58  VAL A O     1 
ATOM   435   C  CB    . VAL A 1 58  ? -18.844 -26.827 -1.665   1.00 51.89  ? 58  VAL A CB    1 
ATOM   436   C  CG1   . VAL A 1 58  ? -18.585 -25.393 -2.075   1.00 66.15  ? 58  VAL A CG1   1 
ATOM   437   C  CG2   . VAL A 1 58  ? -18.820 -26.971 -0.154   1.00 55.37  ? 58  VAL A CG2   1 
ATOM   438   N  N     . ALA A 1 59  ? -21.922 -27.786 -0.643   1.00 52.93  ? 59  ALA A N     1 
ATOM   439   C  CA    . ALA A 1 59  ? -23.275 -27.644 -0.130   1.00 48.46  ? 59  ALA A CA    1 
ATOM   440   C  C     . ALA A 1 59  ? -23.236 -27.602 1.388    1.00 49.70  ? 59  ALA A C     1 
ATOM   441   O  O     . ALA A 1 59  ? -23.407 -28.623 2.058    1.00 52.26  ? 59  ALA A O     1 
ATOM   442   C  CB    . ALA A 1 59  ? -24.144 -28.761 -0.633   1.00 48.79  ? 59  ALA A CB    1 
ATOM   443   N  N     . PRO A 1 60  ? -22.972 -26.428 1.988    1.00 48.45  ? 60  PRO A N     1 
ATOM   444   C  CA    . PRO A 1 60  ? -22.842 -26.344 3.437    1.00 46.97  ? 60  PRO A CA    1 
ATOM   445   C  C     . PRO A 1 60  ? -24.181 -26.485 4.145    1.00 44.27  ? 60  PRO A C     1 
ATOM   446   O  O     . PRO A 1 60  ? -25.242 -26.372 3.533    1.00 45.08  ? 60  PRO A O     1 
ATOM   447   C  CB    . PRO A 1 60  ? -22.194 -24.975 3.652    1.00 48.10  ? 60  PRO A CB    1 
ATOM   448   C  CG    . PRO A 1 60  ? -22.701 -24.157 2.482    1.00 48.23  ? 60  PRO A CG    1 
ATOM   449   C  CD    . PRO A 1 60  ? -22.772 -25.135 1.326    1.00 48.67  ? 60  PRO A CD    1 
ATOM   450   N  N     . ALA A 1 61  ? -24.085 -26.775 5.448    1.00 50.77  ? 61  ALA A N     1 
ATOM   451   C  CA    . ALA A 1 61  ? -25.225 -27.035 6.315    1.00 51.01  ? 61  ALA A CA    1 
ATOM   452   C  C     . ALA A 1 61  ? -25.564 -25.819 7.171    1.00 49.88  ? 61  ALA A C     1 
ATOM   453   O  O     . ALA A 1 61  ? -26.632 -25.792 7.771    1.00 48.63  ? 61  ALA A O     1 
ATOM   454   C  CB    . ALA A 1 61  ? -24.923 -28.202 7.218    1.00 49.29  ? 61  ALA A CB    1 
ATOM   455   N  N     . SER A 1 62  ? -24.655 -24.837 7.263    1.00 46.83  ? 62  SER A N     1 
ATOM   456   C  CA    . SER A 1 62  ? -24.858 -23.745 8.199    1.00 46.06  ? 62  SER A CA    1 
ATOM   457   C  C     . SER A 1 62  ? -24.129 -22.494 7.745    1.00 42.11  ? 62  SER A C     1 
ATOM   458   O  O     . SER A 1 62  ? -23.176 -22.545 6.966    1.00 49.31  ? 62  SER A O     1 
ATOM   459   C  CB    . SER A 1 62  ? -24.354 -24.135 9.553    1.00 49.12  ? 62  SER A CB    1 
ATOM   460   O  OG    . SER A 1 62  ? -22.939 -24.308 9.510    1.00 54.05  ? 62  SER A OG    1 
ATOM   461   N  N     . THR A 1 63  ? -24.513 -21.391 8.364    1.00 39.21  ? 63  THR A N     1 
ATOM   462   C  CA    . THR A 1 63  ? -23.848 -20.123 8.169    1.00 39.15  ? 63  THR A CA    1 
ATOM   463   C  C     . THR A 1 63  ? -22.359 -20.237 8.459    1.00 41.67  ? 63  THR A C     1 
ATOM   464   O  O     . THR A 1 63  ? -21.532 -19.647 7.766    1.00 41.89  ? 63  THR A O     1 
ATOM   465   C  CB    . THR A 1 63  ? -24.472 -19.044 9.057    1.00 39.16  ? 63  THR A CB    1 
ATOM   466   O  OG1   . THR A 1 63  ? -25.790 -18.807 8.558    1.00 41.40  ? 63  THR A OG1   1 
ATOM   467   C  CG2   . THR A 1 63  ? -23.672 -17.757 9.055    1.00 42.27  ? 63  THR A CG2   1 
ATOM   468   N  N     . GLU A 1 64  ? -22.022 -20.920 9.550    1.00 47.50  ? 64  GLU A N     1 
ATOM   469   C  CA    . GLU A 1 64  ? -20.641 -20.924 9.991    1.00 47.79  ? 64  GLU A CA    1 
ATOM   470   C  C     . GLU A 1 64  ? -19.799 -21.725 8.986    1.00 41.76  ? 64  GLU A C     1 
ATOM   471   O  O     . GLU A 1 64  ? -18.646 -21.385 8.745    1.00 45.16  ? 64  GLU A O     1 
ATOM   472   C  CB    . GLU A 1 64  ? -20.562 -21.397 11.448   1.00 49.32  ? 64  GLU A CB    1 
ATOM   473   C  CG    . GLU A 1 64  ? -19.303 -20.926 12.167   1.00 51.07  ? 64  GLU A CG    1 
ATOM   474   C  CD    . GLU A 1 64  ? -17.983 -21.562 11.748   1.00 45.61  ? 64  GLU A CD    1 
ATOM   475   O  OE1   . GLU A 1 64  ? -17.975 -22.782 11.551   1.00 49.78  ? 64  GLU A OE1   1 
ATOM   476   O  OE2   . GLU A 1 64  ? -16.961 -20.844 11.676   1.00 46.17  ? 64  GLU A OE2   1 
ATOM   477   N  N     . GLU A 1 65  ? -20.386 -22.753 8.376    1.00 41.30  ? 65  GLU A N     1 
ATOM   478   C  CA    . GLU A 1 65  ? -19.713 -23.501 7.326    1.00 48.48  ? 65  GLU A CA    1 
ATOM   479   C  C     . GLU A 1 65  ? -19.517 -22.604 6.109    1.00 51.15  ? 65  GLU A C     1 
ATOM   480   O  O     . GLU A 1 65  ? -18.441 -22.623 5.515    1.00 45.16  ? 65  GLU A O     1 
ATOM   481   C  CB    . GLU A 1 65  ? -20.472 -24.776 6.956    1.00 49.09  ? 65  GLU A CB    1 
ATOM   482   C  CG    . GLU A 1 65  ? -20.375 -25.829 8.047    1.00 53.16  ? 65  GLU A CG    1 
ATOM   483   C  CD    . GLU A 1 65  ? -21.096 -27.136 7.770    1.00 56.27  ? 65  GLU A CD    1 
ATOM   484   O  OE1   . GLU A 1 65  ? -21.593 -27.318 6.646    1.00 61.79  ? 65  GLU A OE1   1 
ATOM   485   O  OE2   . GLU A 1 65  ? -21.197 -27.949 8.704    1.00 62.54  ? 65  GLU A OE2   1 
ATOM   486   N  N     . VAL A 1 66  ? -20.531 -21.797 5.774    1.00 42.74  ? 66  VAL A N     1 
ATOM   487   C  CA    . VAL A 1 66  ? -20.372 -20.811 4.715    1.00 43.23  ? 66  VAL A CA    1 
ATOM   488   C  C     . VAL A 1 66  ? -19.151 -19.932 4.982    1.00 41.91  ? 66  VAL A C     1 
ATOM   489   O  O     . VAL A 1 66  ? -18.352 -19.694 4.080    1.00 46.23  ? 66  VAL A O     1 
ATOM   490   C  CB    . VAL A 1 66  ? -21.636 -19.950 4.537    1.00 40.52  ? 66  VAL A CB    1 
ATOM   491   C  CG1   . VAL A 1 66  ? -21.342 -18.722 3.699    1.00 41.35  ? 66  VAL A CG1   1 
ATOM   492   C  CG2   . VAL A 1 66  ? -22.774 -20.751 3.939    1.00 35.76  ? 66  VAL A CG2   1 
ATOM   493   N  N     . GLN A 1 67  ? -19.016 -19.449 6.217    1.00 46.63  ? 67  GLN A N     1 
ATOM   494   C  CA    . GLN A 1 67  ? -17.930 -18.550 6.576    1.00 45.88  ? 67  GLN A CA    1 
ATOM   495   C  C     . GLN A 1 67  ? -16.579 -19.226 6.403    1.00 43.39  ? 67  GLN A C     1 
ATOM   496   O  O     . GLN A 1 67  ? -15.624 -18.574 6.003    1.00 46.80  ? 67  GLN A O     1 
ATOM   497   C  CB    . GLN A 1 67  ? -18.032 -18.095 8.034    1.00 53.26  ? 67  GLN A CB    1 
ATOM   498   C  CG    . GLN A 1 67  ? -19.176 -17.126 8.325    1.00 51.55  ? 67  GLN A CG    1 
ATOM   499   C  CD    . GLN A 1 67  ? -19.316 -16.882 9.810    1.00 42.33  ? 67  GLN A CD    1 
ATOM   500   O  OE1   . GLN A 1 67  ? -20.117 -17.514 10.472   1.00 39.66  ? 67  GLN A OE1   1 
ATOM   501   N  NE2   . GLN A 1 67  ? -18.496 -16.007 10.362   1.00 47.13  ? 67  GLN A NE2   1 
ATOM   502   N  N     . GLU A 1 68  ? -16.478 -20.510 6.771    1.00 50.86  ? 68  GLU A N     1 
ATOM   503   C  CA    . GLU A 1 68  ? -15.206 -21.220 6.658    1.00 51.49  ? 68  GLU A CA    1 
ATOM   504   C  C     . GLU A 1 68  ? -14.872 -21.466 5.188    1.00 46.46  ? 68  GLU A C     1 
ATOM   505   O  O     . GLU A 1 68  ? -13.717 -21.322 4.771    1.00 44.68  ? 68  GLU A O     1 
ATOM   506   C  CB    . GLU A 1 68  ? -15.222 -22.520 7.453    1.00 51.37  ? 68  GLU A CB    1 
ATOM   507   C  CG    . GLU A 1 68  ? -15.233 -22.289 8.950    1.00 57.54  ? 68  GLU A CG    1 
ATOM   508   C  CD    . GLU A 1 68  ? -14.943 -23.530 9.774    1.00 60.21  ? 68  GLU A CD    1 
ATOM   509   O  OE1   . GLU A 1 68  ? -13.782 -23.992 9.746    1.00 70.36  ? 68  GLU A OE1   1 
ATOM   510   O  OE2   . GLU A 1 68  ? -15.874 -24.034 10.436   1.00 51.39  ? 68  GLU A OE2   1 
ATOM   511   N  N     . ILE A 1 69  ? -15.902 -21.767 4.396    1.00 43.72  ? 69  ILE A N     1 
ATOM   512   C  CA    . ILE A 1 69  ? -15.720 -21.934 2.961    1.00 49.21  ? 69  ILE A CA    1 
ATOM   513   C  C     . ILE A 1 69  ? -15.109 -20.645 2.421    1.00 49.48  ? 69  ILE A C     1 
ATOM   514   O  O     . ILE A 1 69  ? -14.085 -20.682 1.746    1.00 54.47  ? 69  ILE A O     1 
ATOM   515   C  CB    . ILE A 1 69  ? -17.048 -22.320 2.270    1.00 46.00  ? 69  ILE A CB    1 
ATOM   516   C  CG1   . ILE A 1 69  ? -17.480 -23.747 2.641    1.00 44.64  ? 69  ILE A CG1   1 
ATOM   517   C  CG2   . ILE A 1 69  ? -16.942 -22.119 0.765    1.00 46.47  ? 69  ILE A CG2   1 
ATOM   518   C  CD1   . ILE A 1 69  ? -18.924 -24.107 2.306    1.00 43.65  ? 69  ILE A CD1   1 
ATOM   519   N  N     . VAL A 1 70  ? -15.721 -19.508 2.775    1.00 45.96  ? 70  VAL A N     1 
ATOM   520   C  CA    . VAL A 1 70  ? -15.296 -18.228 2.239    1.00 43.79  ? 70  VAL A CA    1 
ATOM   521   C  C     . VAL A 1 70  ? -13.872 -17.946 2.698    1.00 46.28  ? 70  VAL A C     1 
ATOM   522   O  O     . VAL A 1 70  ? -13.078 -17.362 1.956    1.00 45.40  ? 70  VAL A O     1 
ATOM   523   C  CB    . VAL A 1 70  ? -16.237 -17.082 2.648    1.00 38.61  ? 70  VAL A CB    1 
ATOM   524   C  CG1   . VAL A 1 70  ? -15.646 -15.729 2.307    1.00 42.04  ? 70  VAL A CG1   1 
ATOM   525   C  CG2   . VAL A 1 70  ? -17.601 -17.246 2.015    1.00 37.38  ? 70  VAL A CG2   1 
ATOM   526   N  N     . ARG A 1 71  ? -13.555 -18.297 3.944    1.00 45.00  ? 71  ARG A N     1 
ATOM   527   C  CA    . ARG A 1 71  ? -12.190 -18.071 4.391    1.00 46.64  ? 71  ARG A CA    1 
ATOM   528   C  C     . ARG A 1 71  ? -11.261 -18.945 3.548    1.00 46.36  ? 71  ARG A C     1 
ATOM   529   O  O     . ARG A 1 71  ? -10.202 -18.490 3.131    1.00 47.88  ? 71  ARG A O     1 
ATOM   530   C  CB    . ARG A 1 71  ? -12.040 -18.313 5.896    1.00 50.12  ? 71  ARG A CB    1 
ATOM   531   C  CG    . ARG A 1 71  ? -12.568 -17.179 6.764    1.00 52.43  ? 71  ARG A CG    1 
ATOM   532   C  CD    . ARG A 1 71  ? -12.516 -17.444 8.256    1.00 50.58  ? 71  ARG A CD    1 
ATOM   533   N  NE    . ARG A 1 71  ? -13.304 -16.452 8.988    1.00 51.99  ? 71  ARG A NE    1 
ATOM   534   C  CZ    . ARG A 1 71  ? -14.206 -16.738 9.924    1.00 52.26  ? 71  ARG A CZ    1 
ATOM   535   N  NH1   . ARG A 1 71  ? -14.283 -17.964 10.410   1.00 49.60  ? 71  ARG A NH1   1 
ATOM   536   N  NH2   . ARG A 1 71  ? -15.000 -15.786 10.400   1.00 50.47  ? 71  ARG A NH2   1 
ATOM   537   N  N     . VAL A 1 72  ? -11.679 -20.177 3.237    1.00 46.17  ? 72  VAL A N     1 
ATOM   538   C  CA    . VAL A 1 72  ? -10.820 -21.046 2.448    1.00 51.93  ? 72  VAL A CA    1 
ATOM   539   C  C     . VAL A 1 72  ? -10.691 -20.499 1.029    1.00 50.45  ? 72  VAL A C     1 
ATOM   540   O  O     . VAL A 1 72  ? -9.576  -20.358 0.513    1.00 56.25  ? 72  VAL A O     1 
ATOM   541   C  CB    . VAL A 1 72  ? -11.297 -22.505 2.469    1.00 46.89  ? 72  VAL A CB    1 
ATOM   542   C  CG1   . VAL A 1 72  ? -10.746 -23.302 1.296    1.00 50.80  ? 72  VAL A CG1   1 
ATOM   543   C  CG2   . VAL A 1 72  ? -10.928 -23.153 3.789    1.00 46.55  ? 72  VAL A CG2   1 
ATOM   544   N  N     . ALA A 1 73  ? -11.826 -20.142 0.422    1.00 44.95  ? 73  ALA A N     1 
ATOM   545   C  CA    . ALA A 1 73  ? -11.794 -19.539 -0.900   1.00 43.92  ? 73  ALA A CA    1 
ATOM   546   C  C     . ALA A 1 73  ? -10.770 -18.407 -0.948   1.00 46.45  ? 73  ALA A C     1 
ATOM   547   O  O     . ALA A 1 73  ? -10.041 -18.273 -1.926   1.00 51.99  ? 73  ALA A O     1 
ATOM   548   C  CB    . ALA A 1 73  ? -13.161 -19.053 -1.280   1.00 47.40  ? 73  ALA A CB    1 
ATOM   549   N  N     . ASN A 1 74  ? -10.744 -17.564 0.091    1.00 45.89  ? 74  ASN A N     1 
ATOM   550   C  CA    . ASN A 1 74  ? -9.812  -16.450 0.140    1.00 47.19  ? 74  ASN A CA    1 
ATOM   551   C  C     . ASN A 1 74  ? -8.362  -16.954 0.142    1.00 52.07  ? 74  ASN A C     1 
ATOM   552   O  O     . ASN A 1 74  ? -7.491  -16.334 -0.474   1.00 49.88  ? 74  ASN A O     1 
ATOM   553   C  CB    . ASN A 1 74  ? -10.078 -15.552 1.352    1.00 46.43  ? 74  ASN A CB    1 
ATOM   554   C  CG    . ASN A 1 74  ? -11.099 -14.461 1.089    1.00 49.49  ? 74  ASN A CG    1 
ATOM   555   O  OD1   . ASN A 1 74  ? -10.768 -13.430 0.508    1.00 45.61  ? 74  ASN A OD1   1 
ATOM   556   N  ND2   . ASN A 1 74  ? -12.343 -14.691 1.486    1.00 47.36  ? 74  ASN A ND2   1 
ATOM   557   N  N     . GLU A 1 75  ? -8.080  -18.051 0.862    1.00 55.46  ? 75  GLU A N     1 
ATOM   558   C  CA    . GLU A 1 75  ? -6.699  -18.486 1.023    1.00 64.14  ? 75  GLU A CA    1 
ATOM   559   C  C     . GLU A 1 75  ? -6.151  -19.033 -0.297   1.00 60.80  ? 75  GLU A C     1 
ATOM   560   O  O     . GLU A 1 75  ? -4.978  -18.854 -0.586   1.00 67.28  ? 75  GLU A O     1 
ATOM   561   C  CB    . GLU A 1 75  ? -6.534  -19.543 2.114    1.00 70.26  ? 75  GLU A CB    1 
ATOM   562   C  CG    . GLU A 1 75  ? -5.072  -19.794 2.438    1.00 76.20  ? 75  GLU A CG    1 
ATOM   563   C  CD    . GLU A 1 75  ? -4.810  -20.622 3.684    1.00 85.73  ? 75  GLU A CD    1 
ATOM   564   O  OE1   . GLU A 1 75  ? -4.368  -20.030 4.692    1.00 98.50  ? 75  GLU A OE1   1 
ATOM   565   O  OE2   . GLU A 1 75  ? -5.031  -21.851 3.639    1.00 73.63  ? 75  GLU A OE2   1 
ATOM   566   N  N     . PHE A 1 76  ? -7.004  -19.679 -1.096   1.00 61.34  ? 76  PHE A N     1 
ATOM   567   C  CA    . PHE A 1 76  ? -6.567  -20.353 -2.308   1.00 60.57  ? 76  PHE A CA    1 
ATOM   568   C  C     . PHE A 1 76  ? -6.939  -19.595 -3.578   1.00 56.52  ? 76  PHE A C     1 
ATOM   569   O  O     . PHE A 1 76  ? -6.641  -20.087 -4.651   1.00 52.35  ? 76  PHE A O     1 
ATOM   570   C  CB    . PHE A 1 76  ? -7.129  -21.773 -2.325   1.00 59.32  ? 76  PHE A CB    1 
ATOM   571   C  CG    . PHE A 1 76  ? -6.465  -22.596 -1.261   1.00 65.05  ? 76  PHE A CG    1 
ATOM   572   C  CD1   . PHE A 1 76  ? -5.169  -23.049 -1.444   1.00 67.37  ? 76  PHE A CD1   1 
ATOM   573   C  CD2   . PHE A 1 76  ? -7.070  -22.782 -0.031   1.00 67.41  ? 76  PHE A CD2   1 
ATOM   574   C  CE1   . PHE A 1 76  ? -4.520  -23.743 -0.439   1.00 69.57  ? 76  PHE A CE1   1 
ATOM   575   C  CE2   . PHE A 1 76  ? -6.418  -23.472 0.976    1.00 70.56  ? 76  PHE A CE2   1 
ATOM   576   C  CZ    . PHE A 1 76  ? -5.144  -23.950 0.770    1.00 73.78  ? 76  PHE A CZ    1 
ATOM   577   N  N     . GLY A 1 77  ? -7.592  -18.429 -3.463   1.00 55.11  ? 77  GLY A N     1 
ATOM   578   C  CA    . GLY A 1 77  ? -7.927  -17.622 -4.624   1.00 52.22  ? 77  GLY A CA    1 
ATOM   579   C  C     . GLY A 1 77  ? -8.982  -18.277 -5.506   1.00 50.48  ? 77  GLY A C     1 
ATOM   580   O  O     . GLY A 1 77  ? -9.047  -17.983 -6.690   1.00 62.36  ? 77  GLY A O     1 
ATOM   581   N  N     . VAL A 1 78  ? -9.811  -19.154 -4.930   1.00 48.35  ? 78  VAL A N     1 
ATOM   582   C  CA    . VAL A 1 78  ? -10.810 -19.884 -5.693   1.00 48.07  ? 78  VAL A CA    1 
ATOM   583   C  C     . VAL A 1 78  ? -12.145 -19.147 -5.629   1.00 47.46  ? 78  VAL A C     1 
ATOM   584   O  O     . VAL A 1 78  ? -12.699 -18.911 -4.555   1.00 47.45  ? 78  VAL A O     1 
ATOM   585   C  CB    . VAL A 1 78  ? -10.961 -21.323 -5.162   1.00 53.69  ? 78  VAL A CB    1 
ATOM   586   C  CG1   . VAL A 1 78  ? -12.180 -22.020 -5.752   1.00 56.96  ? 78  VAL A CG1   1 
ATOM   587   C  CG2   . VAL A 1 78  ? -9.709  -22.147 -5.405   1.00 55.73  ? 78  VAL A CG2   1 
ATOM   588   N  N     . PRO A 1 79  ? -12.744 -18.778 -6.772   1.00 49.74  ? 79  PRO A N     1 
ATOM   589   C  CA    . PRO A 1 79  ? -14.046 -18.116 -6.752   1.00 48.17  ? 79  PRO A CA    1 
ATOM   590   C  C     . PRO A 1 79  ? -15.238 -19.005 -6.435   1.00 47.57  ? 79  PRO A C     1 
ATOM   591   O  O     . PRO A 1 79  ? -15.267 -20.168 -6.846   1.00 45.50  ? 79  PRO A O     1 
ATOM   592   C  CB    . PRO A 1 79  ? -14.206 -17.616 -8.190   1.00 52.58  ? 79  PRO A CB    1 
ATOM   593   C  CG    . PRO A 1 79  ? -13.344 -18.569 -9.001   1.00 51.07  ? 79  PRO A CG    1 
ATOM   594   C  CD    . PRO A 1 79  ? -12.158 -18.857 -8.117   1.00 52.02  ? 79  PRO A CD    1 
ATOM   595   N  N     . LEU A 1 80  ? -16.249 -18.384 -5.808   1.00 42.05  ? 80  LEU A N     1 
ATOM   596   C  CA    . LEU A 1 80  ? -17.496 -19.033 -5.428   1.00 46.31  ? 80  LEU A CA    1 
ATOM   597   C  C     . LEU A 1 80  ? -18.677 -18.373 -6.126   1.00 43.23  ? 80  LEU A C     1 
ATOM   598   O  O     . LEU A 1 80  ? -18.689 -17.157 -6.311   1.00 46.69  ? 80  LEU A O     1 
ATOM   599   C  CB    . LEU A 1 80  ? -17.682 -18.903 -3.916   1.00 45.18  ? 80  LEU A CB    1 
ATOM   600   C  CG    . LEU A 1 80  ? -16.575 -19.509 -3.071   1.00 47.97  ? 80  LEU A CG    1 
ATOM   601   C  CD1   . LEU A 1 80  ? -16.759 -19.146 -1.597   1.00 49.43  ? 80  LEU A CD1   1 
ATOM   602   C  CD2   . LEU A 1 80  ? -16.555 -21.015 -3.263   1.00 50.89  ? 80  LEU A CD2   1 
ATOM   603   N  N     . TRP A 1 81  ? -19.673 -19.186 -6.489   1.00 46.18  ? 81  TRP A N     1 
ATOM   604   C  CA    . TRP A 1 81  ? -20.918 -18.684 -7.051   1.00 48.55  ? 81  TRP A CA    1 
ATOM   605   C  C     . TRP A 1 81  ? -22.049 -19.167 -6.153   1.00 46.24  ? 81  TRP A C     1 
ATOM   606   O  O     . TRP A 1 81  ? -22.466 -20.322 -6.215   1.00 51.24  ? 81  TRP A O     1 
ATOM   607   C  CB    . TRP A 1 81  ? -21.114 -19.063 -8.542   1.00 48.12  ? 81  TRP A CB    1 
ATOM   608   C  CG    . TRP A 1 81  ? -22.296 -18.403 -9.196   1.00 47.50  ? 81  TRP A CG    1 
ATOM   609   C  CD1   . TRP A 1 81  ? -23.592 -18.825 -9.165   1.00 51.19  ? 81  TRP A CD1   1 
ATOM   610   C  CD2   . TRP A 1 81  ? -22.305 -17.171 -9.946   1.00 44.85  ? 81  TRP A CD2   1 
ATOM   611   N  NE1   . TRP A 1 81  ? -24.397 -17.960 -9.857   1.00 56.83  ? 81  TRP A NE1   1 
ATOM   612   C  CE2   . TRP A 1 81  ? -23.630 -16.936 -10.348  1.00 47.06  ? 81  TRP A CE2   1 
ATOM   613   C  CE3   . TRP A 1 81  ? -21.309 -16.286 -10.366  1.00 47.91  ? 81  TRP A CE3   1 
ATOM   614   C  CZ2   . TRP A 1 81  ? -24.003 -15.815 -11.087  1.00 50.64  ? 81  TRP A CZ2   1 
ATOM   615   C  CZ3   . TRP A 1 81  ? -21.672 -15.179 -11.093  1.00 45.46  ? 81  TRP A CZ3   1 
ATOM   616   C  CH2   . TRP A 1 81  ? -23.003 -14.941 -11.433  1.00 49.41  ? 81  TRP A CH2   1 
ATOM   617   N  N     . PRO A 1 82  ? -22.547 -18.303 -5.256   1.00 45.64  ? 82  PRO A N     1 
ATOM   618   C  CA    . PRO A 1 82  ? -23.621 -18.680 -4.343   1.00 47.06  ? 82  PRO A CA    1 
ATOM   619   C  C     . PRO A 1 82  ? -24.991 -18.688 -4.999   1.00 51.11  ? 82  PRO A C     1 
ATOM   620   O  O     . PRO A 1 82  ? -25.355 -17.730 -5.685   1.00 51.77  ? 82  PRO A O     1 
ATOM   621   C  CB    . PRO A 1 82  ? -23.594 -17.611 -3.242   1.00 46.81  ? 82  PRO A CB    1 
ATOM   622   C  CG    . PRO A 1 82  ? -22.834 -16.435 -3.825   1.00 46.34  ? 82  PRO A CG    1 
ATOM   623   C  CD    . PRO A 1 82  ? -22.064 -16.931 -5.034   1.00 46.23  ? 82  PRO A CD    1 
ATOM   624   N  N     . VAL A 1 83  ? -25.734 -19.776 -4.747   1.00 48.88  ? 83  VAL A N     1 
ATOM   625   C  CA    . VAL A 1 83  ? -27.135 -19.891 -5.120   1.00 51.00  ? 83  VAL A CA    1 
ATOM   626   C  C     . VAL A 1 83  ? -27.900 -20.395 -3.907   1.00 50.09  ? 83  VAL A C     1 
ATOM   627   O  O     . VAL A 1 83  ? -27.380 -21.217 -3.150   1.00 53.66  ? 83  VAL A O     1 
ATOM   628   C  CB    . VAL A 1 83  ? -27.362 -20.842 -6.309   1.00 56.26  ? 83  VAL A CB    1 
ATOM   629   C  CG1   . VAL A 1 83  ? -26.633 -20.377 -7.552   1.00 56.90  ? 83  VAL A CG1   1 
ATOM   630   C  CG2   . VAL A 1 83  ? -26.987 -22.276 -5.961   1.00 54.66  ? 83  VAL A CG2   1 
ATOM   631   N  N     . SER A 1 84  ? -29.137 -19.915 -3.762   1.00 48.07  ? 84  SER A N     1 
ATOM   632   C  CA    . SER A 1 84  ? -29.988 -20.333 -2.664   1.00 47.30  ? 84  SER A CA    1 
ATOM   633   C  C     . SER A 1 84  ? -30.512 -21.742 -2.913   1.00 51.85  ? 84  SER A C     1 
ATOM   634   O  O     . SER A 1 84  ? -30.300 -22.632 -2.090   1.00 50.38  ? 84  SER A O     1 
ATOM   635   C  CB    . SER A 1 84  ? -31.088 -19.341 -2.426   1.00 47.02  ? 84  SER A CB    1 
ATOM   636   O  OG    . SER A 1 84  ? -30.529 -18.124 -1.943   1.00 49.61  ? 84  SER A OG    1 
ATOM   637   N  N     . ARG A 1 85  ? -31.211 -21.911 -4.038   1.00 48.81  ? 85  ARG A N     1 
ATOM   638   C  CA    . ARG A 1 85  ? -31.698 -23.205 -4.491   1.00 51.82  ? 85  ARG A CA    1 
ATOM   639   C  C     . ARG A 1 85  ? -31.272 -23.459 -5.939   1.00 54.95  ? 85  ARG A C     1 
ATOM   640   O  O     . ARG A 1 85  ? -31.246 -24.609 -6.393   1.00 54.26  ? 85  ARG A O     1 
ATOM   641   C  CB    . ARG A 1 85  ? -33.221 -23.243 -4.357   1.00 47.40  ? 85  ARG A CB    1 
ATOM   642   C  CG    . ARG A 1 85  ? -33.691 -23.418 -2.927   1.00 50.08  ? 85  ARG A CG    1 
ATOM   643   C  CD    . ARG A 1 85  ? -35.200 -23.437 -2.845   1.00 51.05  ? 85  ARG A CD    1 
ATOM   644   N  NE    . ARG A 1 85  ? -35.773 -24.553 -3.576   1.00 52.37  ? 85  ARG A NE    1 
ATOM   645   C  CZ    . ARG A 1 85  ? -35.738 -25.824 -3.196   1.00 54.77  ? 85  ARG A CZ    1 
ATOM   646   N  NH1   . ARG A 1 85  ? -35.055 -26.199 -2.130   1.00 56.39  ? 85  ARG A NH1   1 
ATOM   647   N  NH2   . ARG A 1 85  ? -36.400 -26.725 -3.900   1.00 66.70  ? 85  ARG A NH2   1 
ATOM   648   N  N     . GLY A 1 86  ? -30.997 -22.364 -6.666   1.00 57.39  ? 86  GLY A N     1 
ATOM   649   C  CA    . GLY A 1 86  ? -30.365 -22.436 -7.971   1.00 60.39  ? 86  GLY A CA    1 
ATOM   650   C  C     . GLY A 1 86  ? -31.358 -22.731 -9.093   1.00 56.06  ? 86  GLY A C     1 
ATOM   651   O  O     . GLY A 1 86  ? -30.948 -23.251 -10.127  1.00 53.21  ? 86  GLY A O     1 
ATOM   652   N  N     . LYS A 1 87  ? -32.642 -22.373 -8.888   1.00 53.49  ? 87  LYS A N     1 
ATOM   653   C  CA    . LYS A 1 87  ? -33.697 -22.562 -9.881   1.00 53.59  ? 87  LYS A CA    1 
ATOM   654   C  C     . LYS A 1 87  ? -33.936 -21.289 -10.707  1.00 58.18  ? 87  LYS A C     1 
ATOM   655   O  O     . LYS A 1 87  ? -35.084 -20.986 -11.061  1.00 55.14  ? 87  LYS A O     1 
ATOM   656   C  CB    . LYS A 1 87  ? -35.021 -22.936 -9.203   1.00 52.57  ? 87  LYS A CB    1 
ATOM   657   C  CG    . LYS A 1 87  ? -34.960 -24.043 -8.157   1.00 55.79  ? 87  LYS A CG    1 
ATOM   658   C  CD    . LYS A 1 87  ? -34.515 -25.389 -8.696   1.00 54.38  ? 87  LYS A CD    1 
ATOM   659   C  CE    . LYS A 1 87  ? -34.371 -26.434 -7.608   1.00 54.43  ? 87  LYS A CE    1 
ATOM   660   N  NZ    . LYS A 1 87  ? -33.477 -27.538 -8.027   1.00 52.30  ? 87  LYS A NZ    1 
ATOM   661   N  N     . ASN A 1 88  ? -32.867 -20.546 -11.048  1.00 52.09  ? 88  ASN A N     1 
ATOM   662   C  CA    . ASN A 1 88  ? -33.018 -19.284 -11.764  1.00 52.41  ? 88  ASN A CA    1 
ATOM   663   C  C     . ASN A 1 88  ? -33.178 -19.559 -13.272  1.00 57.26  ? 88  ASN A C     1 
ATOM   664   O  O     . ASN A 1 88  ? -32.405 -19.063 -14.099  1.00 48.61  ? 88  ASN A O     1 
ATOM   665   C  CB    . ASN A 1 88  ? -31.859 -18.333 -11.425  1.00 54.87  ? 88  ASN A CB    1 
ATOM   666   C  CG    . ASN A 1 88  ? -32.214 -16.856 -11.439  1.00 54.16  ? 88  ASN A CG    1 
ATOM   667   O  OD1   . ASN A 1 88  ? -33.384 -16.468 -11.460  1.00 59.18  ? 88  ASN A OD1   1 
ATOM   668   N  ND2   . ASN A 1 88  ? -31.195 -16.013 -11.396  1.00 50.61  ? 88  ASN A ND2   1 
ATOM   669   N  N     . PHE A 1 89  ? -34.236 -20.311 -13.633  1.00 58.81  ? 89  PHE A N     1 
ATOM   670   C  CA    . PHE A 1 89  ? -34.494 -20.747 -15.000  1.00 58.35  ? 89  PHE A CA    1 
ATOM   671   C  C     . PHE A 1 89  ? -34.837 -19.530 -15.864  1.00 60.17  ? 89  PHE A C     1 
ATOM   672   O  O     . PHE A 1 89  ? -35.636 -18.686 -15.443  1.00 54.41  ? 89  PHE A O     1 
ATOM   673   C  CB    . PHE A 1 89  ? -35.587 -21.821 -14.985  1.00 58.15  ? 89  PHE A CB    1 
ATOM   674   C  CG    . PHE A 1 89  ? -35.296 -23.031 -14.121  1.00 63.23  ? 89  PHE A CG    1 
ATOM   675   C  CD1   . PHE A 1 89  ? -34.001 -23.381 -13.768  1.00 67.69  ? 89  PHE A CD1   1 
ATOM   676   C  CD2   . PHE A 1 89  ? -36.333 -23.809 -13.628  1.00 74.01  ? 89  PHE A CD2   1 
ATOM   677   C  CE1   . PHE A 1 89  ? -33.756 -24.499 -12.979  1.00 76.81  ? 89  PHE A CE1   1 
ATOM   678   C  CE2   . PHE A 1 89  ? -36.091 -24.916 -12.827  1.00 67.48  ? 89  PHE A CE2   1 
ATOM   679   C  CZ    . PHE A 1 89  ? -34.801 -25.259 -12.505  1.00 73.25  ? 89  PHE A CZ    1 
ATOM   680   N  N     . ALA A 1 90  ? -34.169 -19.440 -17.035  1.00 55.29  ? 90  ALA A N     1 
ATOM   681   C  CA    . ALA A 1 90  ? -34.248 -18.330 -17.990  1.00 58.88  ? 90  ALA A CA    1 
ATOM   682   C  C     . ALA A 1 90  ? -33.164 -17.277 -17.728  1.00 60.52  ? 90  ALA A C     1 
ATOM   683   O  O     . ALA A 1 90  ? -32.941 -16.378 -18.556  1.00 52.90  ? 90  ALA A O     1 
ATOM   684   C  CB    . ALA A 1 90  ? -35.628 -17.712 -18.012  1.00 57.81  ? 90  ALA A CB    1 
ATOM   685   N  N     . TYR A 1 91  ? -32.464 -17.446 -16.594  1.00 57.10  ? 91  TYR A N     1 
ATOM   686   C  CA    . TYR A 1 91  ? -31.399 -16.554 -16.170  1.00 62.26  ? 91  TYR A CA    1 
ATOM   687   C  C     . TYR A 1 91  ? -30.064 -17.295 -15.992  1.00 53.09  ? 91  TYR A C     1 
ATOM   688   O  O     . TYR A 1 91  ? -29.066 -16.697 -15.588  1.00 50.58  ? 91  TYR A O     1 
ATOM   689   C  CB    . TYR A 1 91  ? -31.871 -15.833 -14.902  1.00 64.20  ? 91  TYR A CB    1 
ATOM   690   C  CG    . TYR A 1 91  ? -33.039 -14.904 -15.130  1.00 64.26  ? 91  TYR A CG    1 
ATOM   691   C  CD1   . TYR A 1 91  ? -32.897 -13.803 -15.956  1.00 65.25  ? 91  TYR A CD1   1 
ATOM   692   C  CD2   . TYR A 1 91  ? -34.282 -15.125 -14.554  1.00 59.72  ? 91  TYR A CD2   1 
ATOM   693   C  CE1   . TYR A 1 91  ? -33.945 -12.932 -16.191  1.00 62.99  ? 91  TYR A CE1   1 
ATOM   694   C  CE2   . TYR A 1 91  ? -35.339 -14.255 -14.770  1.00 56.18  ? 91  TYR A CE2   1 
ATOM   695   C  CZ    . TYR A 1 91  ? -35.161 -13.149 -15.581  1.00 54.09  ? 91  TYR A CZ    1 
ATOM   696   O  OH    . TYR A 1 91  ? -36.144 -12.254 -15.851  1.00 52.07  ? 91  TYR A OH    1 
ATOM   697   N  N     . GLY A 1 92  ? -30.018 -18.593 -16.315  1.00 57.39  ? 92  GLY A N     1 
ATOM   698   C  CA    . GLY A 1 92  ? -28.777 -19.348 -16.181  1.00 57.55  ? 92  GLY A CA    1 
ATOM   699   C  C     . GLY A 1 92  ? -28.871 -20.545 -15.234  1.00 60.50  ? 92  GLY A C     1 
ATOM   700   O  O     . GLY A 1 92  ? -27.887 -21.281 -15.069  1.00 57.71  ? 92  GLY A O     1 
ATOM   701   N  N     . GLY A 1 93  ? -30.052 -20.741 -14.626  1.00 59.00  ? 93  GLY A N     1 
ATOM   702   C  CA    . GLY A 1 93  ? -30.191 -21.655 -13.506  1.00 58.67  ? 93  GLY A CA    1 
ATOM   703   C  C     . GLY A 1 93  ? -29.162 -21.359 -12.415  1.00 58.74  ? 93  GLY A C     1 
ATOM   704   O  O     . GLY A 1 93  ? -29.108 -20.255 -11.873  1.00 61.16  ? 93  GLY A O     1 
ATOM   705   N  N     . ALA A 1 94  ? -28.310 -22.347 -12.148  1.00 55.41  ? 94  ALA A N     1 
ATOM   706   C  CA    . ALA A 1 94  ? -27.393 -22.295 -11.025  1.00 57.50  ? 94  ALA A CA    1 
ATOM   707   C  C     . ALA A 1 94  ? -25.975 -21.991 -11.517  1.00 52.42  ? 94  ALA A C     1 
ATOM   708   O  O     . ALA A 1 94  ? -25.025 -22.006 -10.736  1.00 54.92  ? 94  ALA A O     1 
ATOM   709   C  CB    . ALA A 1 94  ? -27.465 -23.614 -10.283  1.00 55.86  ? 94  ALA A CB    1 
ATOM   710   N  N     . ALA A 1 95  ? -25.836 -21.679 -12.812  1.00 53.78  ? 95  ALA A N     1 
ATOM   711   C  CA    . ALA A 1 95  ? -24.534 -21.673 -13.466  1.00 50.07  ? 95  ALA A CA    1 
ATOM   712   C  C     . ALA A 1 95  ? -23.846 -20.334 -13.258  1.00 47.03  ? 95  ALA A C     1 
ATOM   713   O  O     . ALA A 1 95  ? -24.512 -19.306 -13.264  1.00 52.94  ? 95  ALA A O     1 
ATOM   714   C  CB    . ALA A 1 95  ? -24.690 -21.958 -14.938  1.00 59.26  ? 95  ALA A CB    1 
ATOM   715   N  N     . PRO A 1 96  ? -22.501 -20.290 -13.128  1.00 48.73  ? 96  PRO A N     1 
ATOM   716   C  CA    . PRO A 1 96  ? -21.779 -19.015 -13.025  1.00 53.36  ? 96  PRO A CA    1 
ATOM   717   C  C     . PRO A 1 96  ? -21.629 -18.268 -14.357  1.00 58.84  ? 96  PRO A C     1 
ATOM   718   O  O     . PRO A 1 96  ? -21.632 -18.890 -15.423  1.00 60.99  ? 96  PRO A O     1 
ATOM   719   C  CB    . PRO A 1 96  ? -20.415 -19.491 -12.493  1.00 56.64  ? 96  PRO A CB    1 
ATOM   720   C  CG    . PRO A 1 96  ? -20.223 -20.816 -13.197  1.00 56.91  ? 96  PRO A CG    1 
ATOM   721   C  CD    . PRO A 1 96  ? -21.595 -21.450 -13.085  1.00 54.85  ? 96  PRO A CD    1 
ATOM   722   N  N     . VAL A 1 97  ? -21.469 -16.934 -14.297  1.00 55.09  ? 97  VAL A N     1 
ATOM   723   C  CA    . VAL A 1 97  ? -21.022 -16.167 -15.456  1.00 55.79  ? 97  VAL A CA    1 
ATOM   724   C  C     . VAL A 1 97  ? -19.667 -16.711 -15.933  1.00 54.01  ? 97  VAL A C     1 
ATOM   725   O  O     . VAL A 1 97  ? -19.433 -16.867 -17.126  1.00 44.38  ? 97  VAL A O     1 
ATOM   726   C  CB    . VAL A 1 97  ? -20.924 -14.658 -15.157  1.00 58.79  ? 97  VAL A CB    1 
ATOM   727   C  CG1   . VAL A 1 97  ? -20.276 -13.900 -16.311  1.00 66.75  ? 97  VAL A CG1   1 
ATOM   728   C  CG2   . VAL A 1 97  ? -22.280 -14.039 -14.823  1.00 60.94  ? 97  VAL A CG2   1 
ATOM   729   N  N     . MET A 1 98  ? -18.783 -17.016 -14.986  1.00 51.08  ? 98  MET A N     1 
ATOM   730   C  CA    . MET A 1 98  ? -17.413 -17.326 -15.318  1.00 61.39  ? 98  MET A CA    1 
ATOM   731   C  C     . MET A 1 98  ? -17.177 -18.807 -15.022  1.00 64.68  ? 98  MET A C     1 
ATOM   732   O  O     . MET A 1 98  ? -17.566 -19.282 -13.959  1.00 60.42  ? 98  MET A O     1 
ATOM   733   C  CB    . MET A 1 98  ? -16.466 -16.445 -14.501  1.00 59.14  ? 98  MET A CB    1 
ATOM   734   C  CG    . MET A 1 98  ? -15.054 -16.434 -15.040  1.00 57.88  ? 98  MET A CG    1 
ATOM   735   S  SD    . MET A 1 98  ? -13.855 -15.876 -13.805  1.00 65.14  ? 98  MET A SD    1 
ATOM   736   C  CE    . MET A 1 98  ? -13.886 -17.265 -12.673  1.00 71.09  ? 98  MET A CE    1 
ATOM   737   N  N     . SER A 1 99  ? -16.591 -19.527 -15.999  1.00 61.59  ? 99  SER A N     1 
ATOM   738   C  CA    . SER A 1 99  ? -16.282 -20.949 -15.878  1.00 52.91  ? 99  SER A CA    1 
ATOM   739   C  C     . SER A 1 99  ? -15.176 -21.121 -14.848  1.00 49.24  ? 99  SER A C     1 
ATOM   740   O  O     . SER A 1 99  ? -14.363 -20.226 -14.647  1.00 55.02  ? 99  SER A O     1 
ATOM   741   C  CB    . SER A 1 99  ? -15.851 -21.561 -17.210  1.00 56.12  ? 99  SER A CB    1 
ATOM   742   O  OG    . SER A 1 99  ? -16.892 -21.521 -18.189  1.00 52.53  ? 99  SER A OG    1 
ATOM   743   N  N     . GLY A 1 100 ? -15.137 -22.278 -14.200  1.00 52.31  ? 100 GLY A N     1 
ATOM   744   C  CA    . GLY A 1 100 ? -14.131 -22.519 -13.182  1.00 52.95  ? 100 GLY A CA    1 
ATOM   745   C  C     . GLY A 1 100 ? -14.606 -22.108 -11.789  1.00 53.78  ? 100 GLY A C     1 
ATOM   746   O  O     . GLY A 1 100 ? -13.958 -22.435 -10.806  1.00 56.72  ? 100 GLY A O     1 
ATOM   747   N  N     . THR A 1 101 ? -15.726 -21.379 -11.715  1.00 55.86  ? 101 THR A N     1 
ATOM   748   C  CA    . THR A 1 101 ? -16.256 -20.887 -10.453  1.00 52.98  ? 101 THR A CA    1 
ATOM   749   C  C     . THR A 1 101 ? -16.905 -22.046 -9.706   1.00 54.94  ? 101 THR A C     1 
ATOM   750   O  O     . THR A 1 101 ? -17.726 -22.739 -10.292  1.00 66.94  ? 101 THR A O     1 
ATOM   751   C  CB    . THR A 1 101 ? -17.263 -19.759 -10.716  1.00 53.93  ? 101 THR A CB    1 
ATOM   752   O  OG1   . THR A 1 101 ? -16.632 -18.723 -11.471  1.00 50.90  ? 101 THR A OG1   1 
ATOM   753   C  CG2   . THR A 1 101 ? -17.815 -19.140 -9.455   1.00 59.86  ? 101 THR A CG2   1 
ATOM   754   N  N     . VAL A 1 102 ? -16.532 -22.252 -8.433   1.00 56.84  ? 102 VAL A N     1 
ATOM   755   C  CA    . VAL A 1 102 ? -17.126 -23.290 -7.598   1.00 58.13  ? 102 VAL A CA    1 
ATOM   756   C  C     . VAL A 1 102 ? -18.464 -22.810 -7.054   1.00 59.21  ? 102 VAL A C     1 
ATOM   757   O  O     . VAL A 1 102 ? -18.499 -21.810 -6.339   1.00 60.81  ? 102 VAL A O     1 
ATOM   758   C  CB    . VAL A 1 102 ? -16.215 -23.665 -6.423   1.00 58.26  ? 102 VAL A CB    1 
ATOM   759   C  CG1   . VAL A 1 102 ? -16.859 -24.732 -5.543   1.00 60.47  ? 102 VAL A CG1   1 
ATOM   760   C  CG2   . VAL A 1 102 ? -14.844 -24.090 -6.916   1.00 63.05  ? 102 VAL A CG2   1 
ATOM   761   N  N     . VAL A 1 103 ? -19.541 -23.560 -7.336   1.00 51.35  ? 103 VAL A N     1 
ATOM   762   C  CA    . VAL A 1 103 ? -20.873 -23.180 -6.888   1.00 50.84  ? 103 VAL A CA    1 
ATOM   763   C  C     . VAL A 1 103 ? -20.992 -23.419 -5.379   1.00 58.46  ? 103 VAL A C     1 
ATOM   764   O  O     . VAL A 1 103 ? -20.606 -24.472 -4.877   1.00 49.88  ? 103 VAL A O     1 
ATOM   765   C  CB    . VAL A 1 103 ? -21.970 -23.914 -7.678   1.00 52.92  ? 103 VAL A CB    1 
ATOM   766   C  CG1   . VAL A 1 103 ? -23.349 -23.704 -7.074   1.00 51.43  ? 103 VAL A CG1   1 
ATOM   767   C  CG2   . VAL A 1 103 ? -21.982 -23.506 -9.142   1.00 54.60  ? 103 VAL A CG2   1 
ATOM   768   N  N     . LEU A 1 104 ? -21.488 -22.394 -4.664   1.00 52.56  ? 104 LEU A N     1 
ATOM   769   C  CA    . LEU A 1 104 ? -21.848 -22.485 -3.258   1.00 49.04  ? 104 LEU A CA    1 
ATOM   770   C  C     . LEU A 1 104 ? -23.358 -22.678 -3.171   1.00 45.07  ? 104 LEU A C     1 
ATOM   771   O  O     . LEU A 1 104 ? -24.129 -21.728 -3.281   1.00 47.46  ? 104 LEU A O     1 
ATOM   772   C  CB    . LEU A 1 104 ? -21.385 -21.214 -2.532   1.00 48.60  ? 104 LEU A CB    1 
ATOM   773   C  CG    . LEU A 1 104 ? -21.686 -21.149 -1.031   1.00 54.83  ? 104 LEU A CG    1 
ATOM   774   C  CD1   . LEU A 1 104 ? -20.969 -22.256 -0.281   1.00 54.87  ? 104 LEU A CD1   1 
ATOM   775   C  CD2   . LEU A 1 104 ? -21.313 -19.792 -0.443   1.00 54.79  ? 104 LEU A CD2   1 
ATOM   776   N  N     . ASP A 1 105 ? -23.760 -23.939 -3.020   1.00 44.48  ? 105 ASP A N     1 
ATOM   777   C  CA    . ASP A 1 105 ? -25.154 -24.336 -3.051   1.00 47.16  ? 105 ASP A CA    1 
ATOM   778   C  C     . ASP A 1 105 ? -25.671 -24.423 -1.619   1.00 47.94  ? 105 ASP A C     1 
ATOM   779   O  O     . ASP A 1 105 ? -25.204 -25.226 -0.810   1.00 47.36  ? 105 ASP A O     1 
ATOM   780   C  CB    . ASP A 1 105 ? -25.330 -25.686 -3.754   1.00 50.92  ? 105 ASP A CB    1 
ATOM   781   C  CG    . ASP A 1 105 ? -26.763 -26.180 -3.850   1.00 48.65  ? 105 ASP A CG    1 
ATOM   782   O  OD1   . ASP A 1 105 ? -27.673 -25.463 -3.403   1.00 52.31  ? 105 ASP A OD1   1 
ATOM   783   O  OD2   . ASP A 1 105 ? -26.956 -27.269 -4.406   1.00 57.67  ? 105 ASP A OD2   1 
ATOM   784   N  N     . MET A 1 106 ? -26.696 -23.625 -1.339   1.00 45.18  ? 106 MET A N     1 
ATOM   785   C  CA    . MET A 1 106 ? -27.164 -23.455 0.020    1.00 44.01  ? 106 MET A CA    1 
ATOM   786   C  C     . MET A 1 106 ? -28.527 -24.115 0.191    1.00 44.34  ? 106 MET A C     1 
ATOM   787   O  O     . MET A 1 106 ? -29.216 -23.845 1.163    1.00 42.92  ? 106 MET A O     1 
ATOM   788   C  CB    . MET A 1 106 ? -27.172 -21.956 0.332    1.00 48.42  ? 106 MET A CB    1 
ATOM   789   C  CG    . MET A 1 106 ? -25.751 -21.466 0.632    1.00 50.23  ? 106 MET A CG    1 
ATOM   790   S  SD    . MET A 1 106 ? -25.726 -19.835 1.350    1.00 57.31  ? 106 MET A SD    1 
ATOM   791   C  CE    . MET A 1 106 ? -26.390 -18.946 -0.059   1.00 59.98  ? 106 MET A CE    1 
ATOM   792   N  N     . ASN A 1 107 ? -28.830 -25.068 -0.710   1.00 48.64  ? 107 ASN A N     1 
ATOM   793   C  CA    . ASN A 1 107 ? -30.059 -25.849 -0.714   1.00 51.89  ? 107 ASN A CA    1 
ATOM   794   C  C     . ASN A 1 107 ? -30.365 -26.463 0.647    1.00 44.13  ? 107 ASN A C     1 
ATOM   795   O  O     . ASN A 1 107 ? -31.525 -26.595 0.983    1.00 39.94  ? 107 ASN A O     1 
ATOM   796   C  CB    . ASN A 1 107 ? -30.008 -27.020 -1.712   1.00 61.82  ? 107 ASN A CB    1 
ATOM   797   C  CG    . ASN A 1 107 ? -30.775 -26.745 -2.985   1.00 75.30  ? 107 ASN A CG    1 
ATOM   798   O  OD1   . ASN A 1 107 ? -30.190 -26.606 -4.058   1.00 103.20 ? 107 ASN A OD1   1 
ATOM   799   N  ND2   . ASN A 1 107 ? -32.090 -26.659 -2.873   1.00 80.02  ? 107 ASN A ND2   1 
ATOM   800   N  N     . ARG A 1 108 ? -29.344 -26.947 1.356    1.00 46.21  ? 108 ARG A N     1 
ATOM   801   C  CA    . ARG A 1 108 ? -29.550 -27.715 2.581    1.00 49.83  ? 108 ARG A CA    1 
ATOM   802   C  C     . ARG A 1 108 ? -29.831 -26.794 3.765    1.00 42.82  ? 108 ARG A C     1 
ATOM   803   O  O     . ARG A 1 108 ? -30.250 -27.253 4.812    1.00 42.23  ? 108 ARG A O     1 
ATOM   804   C  CB    . ARG A 1 108 ? -28.314 -28.549 2.949    1.00 45.80  ? 108 ARG A CB    1 
ATOM   805   C  CG    . ARG A 1 108 ? -27.881 -29.556 1.892    1.00 46.79  ? 108 ARG A CG    1 
ATOM   806   C  CD    . ARG A 1 108 ? -26.463 -30.036 2.157    1.00 52.81  ? 108 ARG A CD    1 
ATOM   807   N  NE    . ARG A 1 108 ? -26.462 -30.897 3.336    1.00 53.30  ? 108 ARG A NE    1 
ATOM   808   C  CZ    . ARG A 1 108 ? -25.556 -30.901 4.303    1.00 47.17  ? 108 ARG A CZ    1 
ATOM   809   N  NH1   . ARG A 1 108 ? -24.419 -30.255 4.175    1.00 51.09  ? 108 ARG A NH1   1 
ATOM   810   N  NH2   . ARG A 1 108 ? -25.767 -31.618 5.392    1.00 56.84  ? 108 ARG A NH2   1 
ATOM   811   N  N     . MET A 1 109 ? -29.519 -25.505 3.617    1.00 46.72  ? 109 MET A N     1 
ATOM   812   C  CA    . MET A 1 109 ? -29.862 -24.520 4.626    1.00 38.72  ? 109 MET A CA    1 
ATOM   813   C  C     . MET A 1 109 ? -31.293 -24.100 4.346    1.00 39.86  ? 109 MET A C     1 
ATOM   814   O  O     . MET A 1 109 ? -31.516 -23.036 3.770    1.00 44.99  ? 109 MET A O     1 
ATOM   815   C  CB    . MET A 1 109 ? -28.917 -23.313 4.554    1.00 42.57  ? 109 MET A CB    1 
ATOM   816   C  CG    . MET A 1 109 ? -27.506 -23.673 4.958    1.00 43.61  ? 109 MET A CG    1 
ATOM   817   S  SD    . MET A 1 109 ? -26.260 -22.419 4.617    1.00 47.62  ? 109 MET A SD    1 
ATOM   818   C  CE    . MET A 1 109 ? -26.822 -21.146 5.750    1.00 44.30  ? 109 MET A CE    1 
ATOM   819   N  N     . ASN A 1 110 ? -32.241 -24.954 4.755    1.00 39.55  ? 110 ASN A N     1 
ATOM   820   C  CA    . ASN A 1 110 ? -33.639 -24.819 4.365    1.00 43.50  ? 110 ASN A CA    1 
ATOM   821   C  C     . ASN A 1 110 ? -34.552 -24.737 5.581    1.00 37.68  ? 110 ASN A C     1 
ATOM   822   O  O     . ASN A 1 110 ? -35.729 -25.044 5.482    1.00 42.23  ? 110 ASN A O     1 
ATOM   823   C  CB    . ASN A 1 110 ? -34.101 -25.966 3.461    1.00 47.10  ? 110 ASN A CB    1 
ATOM   824   C  CG    . ASN A 1 110 ? -33.969 -27.331 4.105    1.00 49.74  ? 110 ASN A CG    1 
ATOM   825   O  OD1   . ASN A 1 110 ? -33.226 -27.513 5.071    1.00 51.77  ? 110 ASN A OD1   1 
ATOM   826   N  ND2   . ASN A 1 110 ? -34.658 -28.303 3.542    1.00 49.44  ? 110 ASN A ND2   1 
ATOM   827   N  N     . ARG A 1 111 ? -34.030 -24.255 6.712    1.00 44.99  ? 111 ARG A N     1 
ATOM   828   C  CA    . ARG A 1 111 ? -34.868 -24.063 7.886    1.00 48.95  ? 111 ARG A CA    1 
ATOM   829   C  C     . ARG A 1 111 ? -35.720 -22.806 7.719    1.00 49.75  ? 111 ARG A C     1 
ATOM   830   O  O     . ARG A 1 111 ? -35.240 -21.732 7.337    1.00 53.30  ? 111 ARG A O     1 
ATOM   831   C  CB    . ARG A 1 111 ? -34.015 -23.951 9.153    1.00 59.19  ? 111 ARG A CB    1 
ATOM   832   C  CG    . ARG A 1 111 ? -33.335 -25.243 9.595    1.00 64.16  ? 111 ARG A CG    1 
ATOM   833   C  CD    . ARG A 1 111 ? -32.319 -24.971 10.696   1.00 67.96  ? 111 ARG A CD    1 
ATOM   834   N  NE    . ARG A 1 111 ? -31.092 -24.423 10.125   1.00 78.09  ? 111 ARG A NE    1 
ATOM   835   C  CZ    . ARG A 1 111 ? -30.185 -25.129 9.442    1.00 76.22  ? 111 ARG A CZ    1 
ATOM   836   N  NH1   . ARG A 1 111 ? -30.164 -26.447 9.530    1.00 76.69  ? 111 ARG A NH1   1 
ATOM   837   N  NH2   . ARG A 1 111 ? -29.262 -24.514 8.719    1.00 64.96  ? 111 ARG A NH2   1 
ATOM   838   N  N     . ILE A 1 112 ? -37.011 -22.995 7.957    1.00 45.09  ? 112 ILE A N     1 
ATOM   839   C  CA    . ILE A 1 112 ? -37.939 -21.927 8.231    1.00 40.43  ? 112 ILE A CA    1 
ATOM   840   C  C     . ILE A 1 112 ? -37.742 -21.568 9.698    1.00 43.06  ? 112 ILE A C     1 
ATOM   841   O  O     . ILE A 1 112 ? -38.206 -22.308 10.545   1.00 47.60  ? 112 ILE A O     1 
ATOM   842   C  CB    . ILE A 1 112 ? -39.361 -22.420 7.909    1.00 39.92  ? 112 ILE A CB    1 
ATOM   843   C  CG1   . ILE A 1 112 ? -39.470 -22.806 6.428    1.00 41.91  ? 112 ILE A CG1   1 
ATOM   844   C  CG2   . ILE A 1 112 ? -40.398 -21.385 8.327    1.00 41.44  ? 112 ILE A CG2   1 
ATOM   845   C  CD1   . ILE A 1 112 ? -40.814 -23.381 5.994    1.00 43.71  ? 112 ILE A CD1   1 
ATOM   846   N  N     . LEU A 1 113 ? -36.999 -20.491 9.992    1.00 41.23  ? 113 LEU A N     1 
ATOM   847   C  CA    . LEU A 1 113 ? -36.614 -20.159 11.359   1.00 43.00  ? 113 LEU A CA    1 
ATOM   848   C  C     . LEU A 1 113 ? -37.809 -19.613 12.140   1.00 44.05  ? 113 LEU A C     1 
ATOM   849   O  O     . LEU A 1 113 ? -37.951 -19.872 13.330   1.00 44.10  ? 113 LEU A O     1 
ATOM   850   C  CB    . LEU A 1 113 ? -35.488 -19.124 11.338   1.00 48.23  ? 113 LEU A CB    1 
ATOM   851   C  CG    . LEU A 1 113 ? -34.171 -19.585 10.713   1.00 56.41  ? 113 LEU A CG    1 
ATOM   852   C  CD1   . LEU A 1 113 ? -33.895 -18.864 9.419    1.00 63.47  ? 113 LEU A CD1   1 
ATOM   853   C  CD2   . LEU A 1 113 ? -33.011 -19.349 11.653   1.00 69.82  ? 113 LEU A CD2   1 
ATOM   854   N  N     . GLU A 1 114 ? -38.661 -18.822 11.485   1.00 39.07  ? 114 GLU A N     1 
ATOM   855   C  CA    . GLU A 1 114 ? -39.851 -18.345 12.151   1.00 40.12  ? 114 GLU A CA    1 
ATOM   856   C  C     . GLU A 1 114 ? -40.901 -17.999 11.108   1.00 38.28  ? 114 GLU A C     1 
ATOM   857   O  O     . GLU A 1 114 ? -40.555 -17.587 10.009   1.00 41.76  ? 114 GLU A O     1 
ATOM   858   C  CB    . GLU A 1 114 ? -39.515 -17.148 13.053   1.00 43.66  ? 114 GLU A CB    1 
ATOM   859   C  CG    . GLU A 1 114 ? -40.620 -16.897 14.068   1.00 51.18  ? 114 GLU A CG    1 
ATOM   860   C  CD    . GLU A 1 114 ? -40.720 -15.506 14.679   1.00 56.54  ? 114 GLU A CD    1 
ATOM   861   O  OE1   . GLU A 1 114 ? -39.742 -14.702 14.557   1.00 53.91  ? 114 GLU A OE1   1 
ATOM   862   O  OE2   . GLU A 1 114 ? -41.793 -15.228 15.261   1.00 50.49  ? 114 GLU A OE2   1 
ATOM   863   N  N     . VAL A 1 115 ? -42.179 -18.233 11.453   1.00 41.28  ? 115 VAL A N     1 
ATOM   864   C  CA    . VAL A 1 115 ? -43.305 -17.641 10.761   1.00 41.40  ? 115 VAL A CA    1 
ATOM   865   C  C     . VAL A 1 115 ? -44.174 -17.024 11.839   1.00 44.68  ? 115 VAL A C     1 
ATOM   866   O  O     . VAL A 1 115 ? -44.611 -17.682 12.768   1.00 42.17  ? 115 VAL A O     1 
ATOM   867   C  CB    . VAL A 1 115 ? -44.126 -18.598 9.873    1.00 43.42  ? 115 VAL A CB    1 
ATOM   868   C  CG1   . VAL A 1 115 ? -45.202 -17.840 9.119    1.00 41.62  ? 115 VAL A CG1   1 
ATOM   869   C  CG2   . VAL A 1 115 ? -43.268 -19.361 8.881    1.00 45.97  ? 115 VAL A CG2   1 
ATOM   870   N  N     . ASN A 1 116 ? -44.397 -15.728 11.710   1.00 43.84  ? 116 ASN A N     1 
ATOM   871   C  CA    . ASN A 1 116 ? -45.105 -14.999 12.733   1.00 40.25  ? 116 ASN A CA    1 
ATOM   872   C  C     . ASN A 1 116 ? -46.436 -14.534 12.168   1.00 38.19  ? 116 ASN A C     1 
ATOM   873   O  O     . ASN A 1 116 ? -46.485 -13.704 11.267   1.00 40.51  ? 116 ASN A O     1 
ATOM   874   C  CB    . ASN A 1 116 ? -44.262 -13.827 13.200   1.00 41.95  ? 116 ASN A CB    1 
ATOM   875   C  CG    . ASN A 1 116 ? -44.808 -13.226 14.465   1.00 37.62  ? 116 ASN A CG    1 
ATOM   876   O  OD1   . ASN A 1 116 ? -45.961 -12.824 14.510   1.00 38.86  ? 116 ASN A OD1   1 
ATOM   877   N  ND2   . ASN A 1 116 ? -43.967 -13.162 15.474   1.00 41.97  ? 116 ASN A ND2   1 
ATOM   878   N  N     . GLU A 1 117 ? -47.518 -15.074 12.690   1.00 36.36  ? 117 GLU A N     1 
ATOM   879   C  CA    . GLU A 1 117 ? -48.811 -14.766 12.121   1.00 35.51  ? 117 GLU A CA    1 
ATOM   880   C  C     . GLU A 1 117 ? -49.220 -13.346 12.508   1.00 38.47  ? 117 GLU A C     1 
ATOM   881   O  O     . GLU A 1 117 ? -49.702 -12.608 11.663   1.00 39.92  ? 117 GLU A O     1 
ATOM   882   C  CB    . GLU A 1 117 ? -49.844 -15.772 12.610   1.00 37.49  ? 117 GLU A CB    1 
ATOM   883   C  CG    . GLU A 1 117 ? -51.234 -15.481 12.102   1.00 43.33  ? 117 GLU A CG    1 
ATOM   884   C  CD    . GLU A 1 117 ? -52.198 -16.588 12.469   1.00 51.31  ? 117 GLU A CD    1 
ATOM   885   O  OE1   . GLU A 1 117 ? -52.156 -16.967 13.626   1.00 55.53  ? 117 GLU A OE1   1 
ATOM   886   O  OE2   . GLU A 1 117 ? -52.961 -17.076 11.592   1.00 53.76  ? 117 GLU A OE2   1 
ATOM   887   N  N     . GLU A 1 118 ? -48.997 -12.984 13.778   1.00 39.23  ? 118 GLU A N     1 
ATOM   888   C  CA    . GLU A 1 118 ? -49.511 -11.760 14.373   1.00 43.26  ? 118 GLU A CA    1 
ATOM   889   C  C     . GLU A 1 118 ? -48.850 -10.547 13.710   1.00 40.03  ? 118 GLU A C     1 
ATOM   890   O  O     . GLU A 1 118 ? -49.484 -9.520  13.541   1.00 41.04  ? 118 GLU A O     1 
ATOM   891   C  CB    . GLU A 1 118 ? -49.235 -11.763 15.884   1.00 51.56  ? 118 GLU A CB    1 
ATOM   892   C  CG    . GLU A 1 118 ? -49.993 -12.838 16.662   1.00 70.11  ? 118 GLU A CG    1 
ATOM   893   C  CD    . GLU A 1 118 ? -49.603 -14.305 16.456   1.00 78.66  ? 118 GLU A CD    1 
ATOM   894   O  OE1   . GLU A 1 118 ? -48.461 -14.585 16.033   1.00 63.83  ? 118 GLU A OE1   1 
ATOM   895   O  OE2   . GLU A 1 118 ? -50.466 -15.185 16.697   1.00 83.06  ? 118 GLU A OE2   1 
ATOM   896   N  N     . PHE A 1 119 ? -47.568 -10.675 13.341   1.00 38.42  ? 119 PHE A N     1 
ATOM   897   C  CA    . PHE A 1 119 ? -46.818 -9.610  12.695   1.00 40.06  ? 119 PHE A CA    1 
ATOM   898   C  C     . PHE A 1 119 ? -46.657 -9.809  11.183   1.00 38.91  ? 119 PHE A C     1 
ATOM   899   O  O     . PHE A 1 119 ? -46.093 -8.942  10.501   1.00 38.34  ? 119 PHE A O     1 
ATOM   900   C  CB    . PHE A 1 119 ? -45.461 -9.491  13.379   1.00 44.53  ? 119 PHE A CB    1 
ATOM   901   C  CG    . PHE A 1 119 ? -45.606 -9.031  14.803   1.00 47.23  ? 119 PHE A CG    1 
ATOM   902   C  CD1   . PHE A 1 119 ? -46.246 -7.833  15.084   1.00 52.43  ? 119 PHE A CD1   1 
ATOM   903   C  CD2   . PHE A 1 119 ? -45.148 -9.804  15.856   1.00 53.26  ? 119 PHE A CD2   1 
ATOM   904   C  CE1   . PHE A 1 119 ? -46.383 -7.402  16.393   1.00 52.03  ? 119 PHE A CE1   1 
ATOM   905   C  CE2   . PHE A 1 119 ? -45.301 -9.373  17.166   1.00 52.94  ? 119 PHE A CE2   1 
ATOM   906   C  CZ    . PHE A 1 119 ? -45.923 -8.179  17.426   1.00 47.66  ? 119 PHE A CZ    1 
ATOM   907   N  N     . GLY A 1 120 ? -47.142 -10.940 10.656   1.00 32.63  ? 120 GLY A N     1 
ATOM   908   C  CA    . GLY A 1 120 ? -47.129 -11.182 9.216    1.00 32.54  ? 120 GLY A CA    1 
ATOM   909   C  C     . GLY A 1 120 ? -45.717 -11.194 8.641    1.00 32.95  ? 120 GLY A C     1 
ATOM   910   O  O     . GLY A 1 120 ? -45.374 -10.342 7.833    1.00 35.53  ? 120 GLY A O     1 
ATOM   911   N  N     . TYR A 1 121 ? -44.890 -12.153 9.073    1.00 34.09  ? 121 TYR A N     1 
ATOM   912   C  CA    . TYR A 1 121 ? -43.581 -12.322 8.478    1.00 32.80  ? 121 TYR A CA    1 
ATOM   913   C  C     . TYR A 1 121 ? -43.070 -13.758 8.599    1.00 34.93  ? 121 TYR A C     1 
ATOM   914   O  O     . TYR A 1 121 ? -43.600 -14.571 9.339    1.00 37.62  ? 121 TYR A O     1 
ATOM   915   C  CB    . TYR A 1 121 ? -42.585 -11.342 9.106    1.00 33.85  ? 121 TYR A CB    1 
ATOM   916   C  CG    . TYR A 1 121 ? -42.142 -11.604 10.522   1.00 32.78  ? 121 TYR A CG    1 
ATOM   917   C  CD1   . TYR A 1 121 ? -41.230 -12.603 10.804   1.00 32.50  ? 121 TYR A CD1   1 
ATOM   918   C  CD2   . TYR A 1 121 ? -42.552 -10.790 11.571   1.00 34.04  ? 121 TYR A CD2   1 
ATOM   919   C  CE1   . TYR A 1 121 ? -40.786 -12.830 12.095   1.00 37.92  ? 121 TYR A CE1   1 
ATOM   920   C  CE2   . TYR A 1 121 ? -42.095 -10.979 12.867   1.00 37.23  ? 121 TYR A CE2   1 
ATOM   921   C  CZ    . TYR A 1 121 ? -41.223 -12.028 13.135   1.00 38.75  ? 121 TYR A CZ    1 
ATOM   922   O  OH    . TYR A 1 121 ? -40.727 -12.301 14.387   1.00 35.89  ? 121 TYR A OH    1 
ATOM   923   N  N     . ALA A 1 122 ? -41.987 -14.018 7.869    1.00 36.85  ? 122 ALA A N     1 
ATOM   924   C  CA    . ALA A 1 122 ? -41.205 -15.234 7.981    1.00 37.37  ? 122 ALA A CA    1 
ATOM   925   C  C     . ALA A 1 122 ? -39.737 -14.837 8.021    1.00 38.78  ? 122 ALA A C     1 
ATOM   926   O  O     . ALA A 1 122 ? -39.352 -13.813 7.463    1.00 38.38  ? 122 ALA A O     1 
ATOM   927   C  CB    . ALA A 1 122 ? -41.478 -16.163 6.821    1.00 32.83  ? 122 ALA A CB    1 
ATOM   928   N  N     . LEU A 1 123 ? -38.951 -15.648 8.724    1.00 37.63  ? 123 LEU A N     1 
ATOM   929   C  CA    . LEU A 1 123 ? -37.506 -15.568 8.664    1.00 37.78  ? 123 LEU A CA    1 
ATOM   930   C  C     . LEU A 1 123 ? -36.997 -16.909 8.145    1.00 44.05  ? 123 LEU A C     1 
ATOM   931   O  O     . LEU A 1 123 ? -37.198 -17.936 8.800    1.00 42.64  ? 123 LEU A O     1 
ATOM   932   C  CB    . LEU A 1 123 ? -36.974 -15.275 10.060   1.00 34.18  ? 123 LEU A CB    1 
ATOM   933   C  CG    . LEU A 1 123 ? -35.449 -15.246 10.216   1.00 34.39  ? 123 LEU A CG    1 
ATOM   934   C  CD1   . LEU A 1 123 ? -34.831 -14.085 9.469    1.00 36.88  ? 123 LEU A CD1   1 
ATOM   935   C  CD2   . LEU A 1 123 ? -35.075 -15.148 11.686   1.00 36.09  ? 123 LEU A CD2   1 
ATOM   936   N  N     . VAL A 1 124 ? -36.315 -16.883 6.993    1.00 41.98  ? 124 VAL A N     1 
ATOM   937   C  CA    . VAL A 1 124 ? -36.029 -18.100 6.255    1.00 44.28  ? 124 VAL A CA    1 
ATOM   938   C  C     . VAL A 1 124 ? -34.557 -18.134 5.871    1.00 43.25  ? 124 VAL A C     1 
ATOM   939   O  O     . VAL A 1 124 ? -33.913 -17.086 5.726    1.00 38.47  ? 124 VAL A O     1 
ATOM   940   C  CB    . VAL A 1 124 ? -36.906 -18.222 4.994    1.00 45.39  ? 124 VAL A CB    1 
ATOM   941   C  CG1   . VAL A 1 124 ? -38.335 -18.615 5.320    1.00 48.77  ? 124 VAL A CG1   1 
ATOM   942   C  CG2   . VAL A 1 124 ? -36.866 -16.949 4.158    1.00 46.28  ? 124 VAL A CG2   1 
ATOM   943   N  N     . GLU A 1 125 ? -34.091 -19.372 5.660    1.00 37.56  ? 125 GLU A N     1 
ATOM   944   C  CA    . GLU A 1 125 ? -32.783 -19.650 5.115    1.00 38.30  ? 125 GLU A CA    1 
ATOM   945   C  C     . GLU A 1 125 ? -32.926 -19.776 3.617    1.00 34.68  ? 125 GLU A C     1 
ATOM   946   O  O     . GLU A 1 125 ? -34.042 -19.929 3.115    1.00 37.90  ? 125 GLU A O     1 
ATOM   947   C  CB    . GLU A 1 125 ? -32.201 -20.936 5.698    1.00 44.36  ? 125 GLU A CB    1 
ATOM   948   C  CG    . GLU A 1 125 ? -31.909 -20.853 7.181    1.00 45.55  ? 125 GLU A CG    1 
ATOM   949   C  CD    . GLU A 1 125 ? -31.130 -22.040 7.727    1.00 50.50  ? 125 GLU A CD    1 
ATOM   950   O  OE1   . GLU A 1 125 ? -31.463 -23.197 7.371    1.00 46.30  ? 125 GLU A OE1   1 
ATOM   951   O  OE2   . GLU A 1 125 ? -30.211 -21.805 8.526    1.00 48.45  ? 125 GLU A OE2   1 
ATOM   952   N  N     . PRO A 1 126 ? -31.802 -19.700 2.877    1.00 31.88  ? 126 PRO A N     1 
ATOM   953   C  CA    . PRO A 1 126 ? -31.829 -19.703 1.416    1.00 38.25  ? 126 PRO A CA    1 
ATOM   954   C  C     . PRO A 1 126 ? -32.441 -20.934 0.742    1.00 39.72  ? 126 PRO A C     1 
ATOM   955   O  O     . PRO A 1 126 ? -33.008 -20.831 -0.349   1.00 41.88  ? 126 PRO A O     1 
ATOM   956   C  CB    . PRO A 1 126 ? -30.344 -19.584 1.044    1.00 38.90  ? 126 PRO A CB    1 
ATOM   957   C  CG    . PRO A 1 126 ? -29.692 -18.974 2.249    1.00 33.86  ? 126 PRO A CG    1 
ATOM   958   C  CD    . PRO A 1 126 ? -30.447 -19.548 3.409    1.00 33.06  ? 126 PRO A CD    1 
ATOM   959   N  N     . GLY A 1 127 ? -32.354 -22.094 1.403    1.00 44.27  ? 127 GLY A N     1 
ATOM   960   C  CA    . GLY A 1 127 ? -32.882 -23.332 0.848    1.00 39.34  ? 127 GLY A CA    1 
ATOM   961   C  C     . GLY A 1 127 ? -34.411 -23.416 0.854    1.00 41.73  ? 127 GLY A C     1 
ATOM   962   O  O     . GLY A 1 127 ? -34.970 -24.268 0.176    1.00 42.25  ? 127 GLY A O     1 
ATOM   963   N  N     . VAL A 1 128 ? -35.112 -22.567 1.620    1.00 39.90  ? 128 VAL A N     1 
ATOM   964   C  CA    . VAL A 1 128 ? -36.564 -22.688 1.697    1.00 37.97  ? 128 VAL A CA    1 
ATOM   965   C  C     . VAL A 1 128 ? -37.192 -22.297 0.359    1.00 43.85  ? 128 VAL A C     1 
ATOM   966   O  O     . VAL A 1 128 ? -36.982 -21.191 -0.146   1.00 45.80  ? 128 VAL A O     1 
ATOM   967   C  CB    . VAL A 1 128 ? -37.161 -21.846 2.831    1.00 37.45  ? 128 VAL A CB    1 
ATOM   968   C  CG1   . VAL A 1 128 ? -38.684 -21.892 2.816    1.00 38.33  ? 128 VAL A CG1   1 
ATOM   969   C  CG2   . VAL A 1 128 ? -36.638 -22.243 4.194    1.00 40.99  ? 128 VAL A CG2   1 
ATOM   970   N  N     . SER A 1 129 ? -38.014 -23.207 -0.177   1.00 43.45  ? 129 SER A N     1 
ATOM   971   C  CA    . SER A 1 129 ? -38.753 -22.996 -1.414   1.00 41.20  ? 129 SER A CA    1 
ATOM   972   C  C     . SER A 1 129 ? -40.104 -22.374 -1.119   1.00 33.63  ? 129 SER A C     1 
ATOM   973   O  O     . SER A 1 129 ? -40.599 -22.433 -0.003   1.00 37.47  ? 129 SER A O     1 
ATOM   974   C  CB    . SER A 1 129 ? -38.981 -24.297 -2.165   1.00 38.39  ? 129 SER A CB    1 
ATOM   975   O  OG    . SER A 1 129 ? -40.076 -25.014 -1.599   1.00 41.18  ? 129 SER A OG    1 
ATOM   976   N  N     . TYR A 1 130 ? -40.741 -21.868 -2.163   1.00 36.40  ? 130 TYR A N     1 
ATOM   977   C  CA    . TYR A 1 130 ? -42.090 -21.349 -2.040   1.00 38.29  ? 130 TYR A CA    1 
ATOM   978   C  C     . TYR A 1 130 ? -43.038 -22.484 -1.677   1.00 41.32  ? 130 TYR A C     1 
ATOM   979   O  O     . TYR A 1 130 ? -43.940 -22.287 -0.862   1.00 38.15  ? 130 TYR A O     1 
ATOM   980   C  CB    . TYR A 1 130 ? -42.491 -20.657 -3.341   1.00 38.52  ? 130 TYR A CB    1 
ATOM   981   C  CG    . TYR A 1 130 ? -41.725 -19.386 -3.614   1.00 42.10  ? 130 TYR A CG    1 
ATOM   982   C  CD1   . TYR A 1 130 ? -42.049 -18.200 -2.967   1.00 36.64  ? 130 TYR A CD1   1 
ATOM   983   C  CD2   . TYR A 1 130 ? -40.688 -19.365 -4.532   1.00 41.96  ? 130 TYR A CD2   1 
ATOM   984   C  CE1   . TYR A 1 130 ? -41.343 -17.031 -3.201   1.00 37.56  ? 130 TYR A CE1   1 
ATOM   985   C  CE2   . TYR A 1 130 ? -40.011 -18.193 -4.824   1.00 43.89  ? 130 TYR A CE2   1 
ATOM   986   C  CZ    . TYR A 1 130 ? -40.326 -17.029 -4.137   1.00 44.51  ? 130 TYR A CZ    1 
ATOM   987   O  OH    . TYR A 1 130 ? -39.664 -15.871 -4.409   1.00 40.16  ? 130 TYR A OH    1 
ATOM   988   N  N     . PHE A 1 131 ? -42.817 -23.670 -2.270   1.00 42.09  ? 131 PHE A N     1 
ATOM   989   C  CA    . PHE A 1 131 ? -43.641 -24.839 -1.969   1.00 38.73  ? 131 PHE A CA    1 
ATOM   990   C  C     . PHE A 1 131 ? -43.565 -25.177 -0.495   1.00 33.62  ? 131 PHE A C     1 
ATOM   991   O  O     . PHE A 1 131 ? -44.600 -25.368 0.126    1.00 38.37  ? 131 PHE A O     1 
ATOM   992   C  CB    . PHE A 1 131 ? -43.266 -26.065 -2.806   1.00 41.08  ? 131 PHE A CB    1 
ATOM   993   C  CG    . PHE A 1 131 ? -43.812 -26.007 -4.201   1.00 38.00  ? 131 PHE A CG    1 
ATOM   994   C  CD1   . PHE A 1 131 ? -45.178 -26.051 -4.416   1.00 42.58  ? 131 PHE A CD1   1 
ATOM   995   C  CD2   . PHE A 1 131 ? -42.975 -25.864 -5.283   1.00 39.17  ? 131 PHE A CD2   1 
ATOM   996   C  CE1   . PHE A 1 131 ? -45.704 -25.987 -5.693   1.00 45.67  ? 131 PHE A CE1   1 
ATOM   997   C  CE2   . PHE A 1 131 ? -43.503 -25.822 -6.563   1.00 41.29  ? 131 PHE A CE2   1 
ATOM   998   C  CZ    . PHE A 1 131 ? -44.865 -25.858 -6.768   1.00 42.08  ? 131 PHE A CZ    1 
ATOM   999   N  N     . GLU A 1 132 ? -42.350 -25.197 0.051    1.00 40.70  ? 132 GLU A N     1 
ATOM   1000  C  CA    . GLU A 1 132 ? -42.137 -25.519 1.449    1.00 40.78  ? 132 GLU A CA    1 
ATOM   1001  C  C     . GLU A 1 132 ? -42.785 -24.497 2.379    1.00 41.10  ? 132 GLU A C     1 
ATOM   1002  O  O     . GLU A 1 132 ? -43.400 -24.888 3.364    1.00 45.75  ? 132 GLU A O     1 
ATOM   1003  C  CB    . GLU A 1 132 ? -40.651 -25.516 1.781    1.00 45.76  ? 132 GLU A CB    1 
ATOM   1004  C  CG    . GLU A 1 132 ? -39.808 -26.627 1.184    1.00 54.60  ? 132 GLU A CG    1 
ATOM   1005  C  CD    . GLU A 1 132 ? -38.332 -26.301 1.408    1.00 64.27  ? 132 GLU A CD    1 
ATOM   1006  O  OE1   . GLU A 1 132 ? -37.989 -25.786 2.525    1.00 66.80  ? 132 GLU A OE1   1 
ATOM   1007  O  OE2   . GLU A 1 132 ? -37.535 -26.508 0.480    1.00 62.31  ? 132 GLU A OE2   1 
ATOM   1008  N  N     . LEU A 1 133 ? -42.563 -23.190 2.133    1.00 44.03  ? 133 LEU A N     1 
ATOM   1009  C  CA    . LEU A 1 133 ? -43.137 -22.144 2.975    1.00 37.31  ? 133 LEU A CA    1 
ATOM   1010  C  C     . LEU A 1 133 ? -44.664 -22.191 2.910    1.00 34.09  ? 133 LEU A C     1 
ATOM   1011  O  O     . LEU A 1 133 ? -45.354 -22.140 3.931    1.00 38.52  ? 133 LEU A O     1 
ATOM   1012  C  CB    . LEU A 1 133 ? -42.584 -20.775 2.548    1.00 35.71  ? 133 LEU A CB    1 
ATOM   1013  C  CG    . LEU A 1 133 ? -43.121 -19.580 3.346    1.00 37.48  ? 133 LEU A CG    1 
ATOM   1014  C  CD1   . LEU A 1 133 ? -42.921 -19.774 4.824    1.00 37.21  ? 133 LEU A CD1   1 
ATOM   1015  C  CD2   . LEU A 1 133 ? -42.467 -18.277 2.892    1.00 41.30  ? 133 LEU A CD2   1 
ATOM   1016  N  N     . TYR A 1 134 ? -45.207 -22.291 1.694    1.00 39.55  ? 134 TYR A N     1 
ATOM   1017  C  CA    . TYR A 1 134 ? -46.645 -22.421 1.509    1.00 41.64  ? 134 TYR A CA    1 
ATOM   1018  C  C     . TYR A 1 134 ? -47.165 -23.619 2.301    1.00 45.88  ? 134 TYR A C     1 
ATOM   1019  O  O     . TYR A 1 134 ? -48.159 -23.488 3.022    1.00 44.52  ? 134 TYR A O     1 
ATOM   1020  C  CB    . TYR A 1 134 ? -46.994 -22.550 0.026    1.00 41.92  ? 134 TYR A CB    1 
ATOM   1021  C  CG    . TYR A 1 134 ? -48.471 -22.654 -0.255   1.00 38.44  ? 134 TYR A CG    1 
ATOM   1022  C  CD1   . TYR A 1 134 ? -49.281 -21.536 -0.268   1.00 38.40  ? 134 TYR A CD1   1 
ATOM   1023  C  CD2   . TYR A 1 134 ? -49.061 -23.881 -0.482   1.00 42.38  ? 134 TYR A CD2   1 
ATOM   1024  C  CE1   . TYR A 1 134 ? -50.639 -21.624 -0.512   1.00 38.25  ? 134 TYR A CE1   1 
ATOM   1025  C  CE2   . TYR A 1 134 ? -50.422 -23.993 -0.703   1.00 43.24  ? 134 TYR A CE2   1 
ATOM   1026  C  CZ    . TYR A 1 134 ? -51.212 -22.864 -0.723   1.00 42.09  ? 134 TYR A CZ    1 
ATOM   1027  O  OH    . TYR A 1 134 ? -52.546 -22.988 -0.976   1.00 41.46  ? 134 TYR A OH    1 
ATOM   1028  N  N     . ASP A 1 135 ? -46.488 -24.780 2.168    1.00 48.40  ? 135 ASP A N     1 
ATOM   1029  C  CA    . ASP A 1 135 ? -46.964 -26.012 2.786    1.00 47.64  ? 135 ASP A CA    1 
ATOM   1030  C  C     . ASP A 1 135 ? -46.877 -25.860 4.308    1.00 46.94  ? 135 ASP A C     1 
ATOM   1031  O  O     . ASP A 1 135 ? -47.785 -26.276 5.005    1.00 49.51  ? 135 ASP A O     1 
ATOM   1032  C  CB    . ASP A 1 135 ? -46.240 -27.278 2.289    1.00 50.74  ? 135 ASP A CB    1 
ATOM   1033  C  CG    . ASP A 1 135 ? -46.475 -27.676 0.834    1.00 49.27  ? 135 ASP A CG    1 
ATOM   1034  O  OD1   . ASP A 1 135 ? -47.604 -27.552 0.342    1.00 45.87  ? 135 ASP A OD1   1 
ATOM   1035  O  OD2   . ASP A 1 135 ? -45.517 -28.117 0.202    1.00 51.19  ? 135 ASP A OD2   1 
ATOM   1036  N  N     . TYR A 1 136 ? -45.807 -25.235 4.820    1.00 45.73  ? 136 TYR A N     1 
ATOM   1037  C  CA    . TYR A 1 136 ? -45.667 -25.000 6.254    1.00 49.76  ? 136 TYR A CA    1 
ATOM   1038  C  C     . TYR A 1 136 ? -46.862 -24.197 6.769    1.00 50.86  ? 136 TYR A C     1 
ATOM   1039  O  O     . TYR A 1 136 ? -47.465 -24.566 7.780    1.00 48.96  ? 136 TYR A O     1 
ATOM   1040  C  CB    . TYR A 1 136 ? -44.325 -24.324 6.549    1.00 52.18  ? 136 TYR A CB    1 
ATOM   1041  C  CG    . TYR A 1 136 ? -44.073 -24.004 7.999    1.00 55.02  ? 136 TYR A CG    1 
ATOM   1042  C  CD1   . TYR A 1 136 ? -44.574 -22.844 8.568    1.00 54.12  ? 136 TYR A CD1   1 
ATOM   1043  C  CD2   . TYR A 1 136 ? -43.352 -24.868 8.805    1.00 58.36  ? 136 TYR A CD2   1 
ATOM   1044  C  CE1   . TYR A 1 136 ? -44.372 -22.551 9.902    1.00 53.37  ? 136 TYR A CE1   1 
ATOM   1045  C  CE2   . TYR A 1 136 ? -43.118 -24.582 10.137   1.00 62.78  ? 136 TYR A CE2   1 
ATOM   1046  C  CZ    . TYR A 1 136 ? -43.630 -23.418 10.684   1.00 63.71  ? 136 TYR A CZ    1 
ATOM   1047  O  OH    . TYR A 1 136 ? -43.433 -23.120 12.005   1.00 65.59  ? 136 TYR A OH    1 
ATOM   1048  N  N     . ILE A 1 137 ? -47.224 -23.129 6.036    1.00 48.04  ? 137 ILE A N     1 
ATOM   1049  C  CA    . ILE A 1 137 ? -48.296 -22.242 6.453    1.00 46.85  ? 137 ILE A CA    1 
ATOM   1050  C  C     . ILE A 1 137 ? -49.617 -23.004 6.459    1.00 44.76  ? 137 ILE A C     1 
ATOM   1051  O  O     . ILE A 1 137 ? -50.422 -22.846 7.380    1.00 44.15  ? 137 ILE A O     1 
ATOM   1052  C  CB    . ILE A 1 137 ? -48.363 -20.978 5.567    1.00 41.27  ? 137 ILE A CB    1 
ATOM   1053  C  CG1   . ILE A 1 137 ? -47.190 -20.043 5.856    1.00 41.32  ? 137 ILE A CG1   1 
ATOM   1054  C  CG2   . ILE A 1 137 ? -49.692 -20.260 5.732    1.00 39.15  ? 137 ILE A CG2   1 
ATOM   1055  C  CD1   . ILE A 1 137 ? -46.999 -18.969 4.824    1.00 41.79  ? 137 ILE A CD1   1 
ATOM   1056  N  N     . GLN A 1 138 ? -49.875 -23.758 5.392    1.00 46.71  ? 138 GLN A N     1 
ATOM   1057  C  CA    . GLN A 1 138 ? -51.136 -24.479 5.262    1.00 47.26  ? 138 GLN A CA    1 
ATOM   1058  C  C     . GLN A 1 138 ? -51.279 -25.465 6.419    1.00 51.34  ? 138 GLN A C     1 
ATOM   1059  O  O     . GLN A 1 138 ? -52.335 -25.519 7.051    1.00 55.15  ? 138 GLN A O     1 
ATOM   1060  C  CB    . GLN A 1 138 ? -51.230 -25.241 3.936    1.00 46.70  ? 138 GLN A CB    1 
ATOM   1061  C  CG    . GLN A 1 138 ? -51.342 -24.365 2.692    1.00 53.67  ? 138 GLN A CG    1 
ATOM   1062  C  CD    . GLN A 1 138 ? -52.262 -23.167 2.779    1.00 56.30  ? 138 GLN A CD    1 
ATOM   1063  O  OE1   . GLN A 1 138 ? -53.485 -23.270 2.830    1.00 64.62  ? 138 GLN A OE1   1 
ATOM   1064  N  NE2   . GLN A 1 138 ? -51.674 -21.990 2.766    1.00 58.09  ? 138 GLN A NE2   1 
ATOM   1065  N  N     . GLU A 1 139 ? -50.189 -26.189 6.716    1.00 51.24  ? 139 GLU A N     1 
ATOM   1066  C  CA    . GLU A 1 139 ? -50.167 -27.191 7.767    1.00 55.24  ? 139 GLU A CA    1 
ATOM   1067  C  C     . GLU A 1 139 ? -50.504 -26.574 9.119    1.00 58.63  ? 139 GLU A C     1 
ATOM   1068  O  O     . GLU A 1 139 ? -51.290 -27.156 9.850    1.00 58.18  ? 139 GLU A O     1 
ATOM   1069  C  CB    . GLU A 1 139 ? -48.812 -27.887 7.847    1.00 58.51  ? 139 GLU A CB    1 
ATOM   1070  C  CG    . GLU A 1 139 ? -48.606 -28.895 6.733    1.00 72.48  ? 139 GLU A CG    1 
ATOM   1071  C  CD    . GLU A 1 139 ? -47.155 -29.217 6.409    1.00 80.50  ? 139 GLU A CD    1 
ATOM   1072  O  OE1   . GLU A 1 139 ? -46.908 -29.727 5.296    1.00 79.14  ? 139 GLU A OE1   1 
ATOM   1073  O  OE2   . GLU A 1 139 ? -46.273 -28.963 7.264    1.00 87.30  ? 139 GLU A OE2   1 
ATOM   1074  N  N     . LYS A 1 140 ? -49.913 -25.416 9.450    1.00 62.69  ? 140 LYS A N     1 
ATOM   1075  C  CA    . LYS A 1 140 ? -50.119 -24.791 10.753   1.00 56.08  ? 140 LYS A CA    1 
ATOM   1076  C  C     . LYS A 1 140 ? -51.426 -24.002 10.772   1.00 48.59  ? 140 LYS A C     1 
ATOM   1077  O  O     . LYS A 1 140 ? -51.868 -23.561 11.824   1.00 57.38  ? 140 LYS A O     1 
ATOM   1078  C  CB    . LYS A 1 140 ? -48.944 -23.885 11.144   1.00 56.42  ? 140 LYS A CB    1 
ATOM   1079  C  CG    . LYS A 1 140 ? -47.562 -24.532 11.079   1.00 63.33  ? 140 LYS A CG    1 
ATOM   1080  C  CD    . LYS A 1 140 ? -47.397 -25.747 11.969   1.00 75.39  ? 140 LYS A CD    1 
ATOM   1081  C  CE    . LYS A 1 140 ? -46.359 -26.717 11.444   1.00 87.43  ? 140 LYS A CE    1 
ATOM   1082  N  NZ    . LYS A 1 140 ? -46.048 -27.784 12.423   1.00 84.62  ? 140 LYS A NZ    1 
ATOM   1083  N  N     . GLY A 1 141 ? -52.058 -23.825 9.615    1.00 49.32  ? 141 GLY A N     1 
ATOM   1084  C  CA    . GLY A 1 141 ? -53.324 -23.110 9.541    1.00 49.80  ? 141 GLY A CA    1 
ATOM   1085  C  C     . GLY A 1 141 ? -53.172 -21.602 9.762    1.00 48.27  ? 141 GLY A C     1 
ATOM   1086  O  O     . GLY A 1 141 ? -54.141 -20.946 10.130   1.00 52.96  ? 141 GLY A O     1 
ATOM   1087  N  N     . LEU A 1 142 ? -51.979 -21.042 9.499    1.00 42.92  ? 142 LEU A N     1 
ATOM   1088  C  CA    . LEU A 1 142 ? -51.759 -19.611 9.672    1.00 46.06  ? 142 LEU A CA    1 
ATOM   1089  C  C     . LEU A 1 142 ? -52.489 -18.827 8.567    1.00 43.28  ? 142 LEU A C     1 
ATOM   1090  O  O     . LEU A 1 142 ? -52.470 -19.205 7.398    1.00 49.44  ? 142 LEU A O     1 
ATOM   1091  C  CB    . LEU A 1 142 ? -50.246 -19.332 9.689    1.00 46.01  ? 142 LEU A CB    1 
ATOM   1092  C  CG    . LEU A 1 142 ? -49.400 -20.165 10.669   1.00 44.58  ? 142 LEU A CG    1 
ATOM   1093  C  CD1   . LEU A 1 142 ? -47.921 -19.829 10.566   1.00 42.27  ? 142 LEU A CD1   1 
ATOM   1094  C  CD2   . LEU A 1 142 ? -49.851 -20.010 12.117   1.00 44.79  ? 142 LEU A CD2   1 
ATOM   1095  N  N     . LYS A 1 143 ? -53.116 -17.701 8.933    1.00 47.79  ? 143 LYS A N     1 
ATOM   1096  C  CA    . LYS A 1 143 ? -53.876 -16.866 8.010    1.00 46.36  ? 143 LYS A CA    1 
ATOM   1097  C  C     . LYS A 1 143 ? -52.934 -15.882 7.309    1.00 44.37  ? 143 LYS A C     1 
ATOM   1098  O  O     . LYS A 1 143 ? -53.037 -14.667 7.459    1.00 39.79  ? 143 LYS A O     1 
ATOM   1099  C  CB    . LYS A 1 143 ? -54.986 -16.104 8.745    1.00 45.73  ? 143 LYS A CB    1 
ATOM   1100  C  CG    . LYS A 1 143 ? -55.865 -16.929 9.665    1.00 52.57  ? 143 LYS A CG    1 
ATOM   1101  C  CD    . LYS A 1 143 ? -56.509 -18.102 8.977    1.00 66.51  ? 143 LYS A CD    1 
ATOM   1102  C  CE    . LYS A 1 143 ? -57.316 -18.986 9.911    1.00 76.46  ? 143 LYS A CE    1 
ATOM   1103  N  NZ    . LYS A 1 143 ? -57.361 -20.380 9.404    1.00 78.59  ? 143 LYS A NZ    1 
ATOM   1104  N  N     . LEU A 1 144 ? -52.042 -16.422 6.489    1.00 39.39  ? 144 LEU A N     1 
ATOM   1105  C  CA    . LEU A 1 144 ? -51.042 -15.643 5.795    1.00 39.11  ? 144 LEU A CA    1 
ATOM   1106  C  C     . LEU A 1 144 ? -50.976 -16.154 4.363    1.00 45.19  ? 144 LEU A C     1 
ATOM   1107  O  O     . LEU A 1 144 ? -51.063 -17.365 4.141    1.00 43.77  ? 144 LEU A O     1 
ATOM   1108  C  CB    . LEU A 1 144 ? -49.686 -15.862 6.478    1.00 36.78  ? 144 LEU A CB    1 
ATOM   1109  C  CG    . LEU A 1 144 ? -49.495 -15.325 7.897    1.00 36.30  ? 144 LEU A CG    1 
ATOM   1110  C  CD1   . LEU A 1 144 ? -48.082 -15.638 8.356    1.00 37.39  ? 144 LEU A CD1   1 
ATOM   1111  C  CD2   . LEU A 1 144 ? -49.746 -13.811 7.963    1.00 36.15  ? 144 LEU A CD2   1 
ATOM   1112  N  N     . TRP A 1 145 ? -50.779 -15.227 3.420    1.00 43.12  ? 145 TRP A N     1 
ATOM   1113  C  CA    . TRP A 1 145 ? -50.472 -15.548 2.034    1.00 41.75  ? 145 TRP A CA    1 
ATOM   1114  C  C     . TRP A 1 145 ? -48.986 -15.308 1.790    1.00 42.21  ? 145 TRP A C     1 
ATOM   1115  O  O     . TRP A 1 145 ? -48.356 -14.449 2.409    1.00 42.53  ? 145 TRP A O     1 
ATOM   1116  C  CB    . TRP A 1 145 ? -51.338 -14.710 1.084    1.00 40.70  ? 145 TRP A CB    1 
ATOM   1117  C  CG    . TRP A 1 145 ? -52.782 -15.123 1.047    1.00 41.04  ? 145 TRP A CG    1 
ATOM   1118  C  CD1   . TRP A 1 145 ? -53.395 -16.034 1.858    1.00 39.91  ? 145 TRP A CD1   1 
ATOM   1119  C  CD2   . TRP A 1 145 ? -53.812 -14.633 0.162    1.00 43.49  ? 145 TRP A CD2   1 
ATOM   1120  N  NE1   . TRP A 1 145 ? -54.718 -16.159 1.524    1.00 40.02  ? 145 TRP A NE1   1 
ATOM   1121  C  CE2   . TRP A 1 145 ? -54.998 -15.336 0.471    1.00 43.22  ? 145 TRP A CE2   1 
ATOM   1122  C  CE3   . TRP A 1 145 ? -53.851 -13.698 -0.874   1.00 47.65  ? 145 TRP A CE3   1 
ATOM   1123  C  CZ2   . TRP A 1 145 ? -56.199 -15.110 -0.198   1.00 46.16  ? 145 TRP A CZ2   1 
ATOM   1124  C  CZ3   . TRP A 1 145 ? -55.038 -13.487 -1.543   1.00 43.80  ? 145 TRP A CZ3   1 
ATOM   1125  C  CH2   . TRP A 1 145 ? -56.193 -14.176 -1.205   1.00 46.22  ? 145 TRP A CH2   1 
ATOM   1126  N  N     . ILE A 1 146 ? -48.419 -16.069 0.864    1.00 39.54  ? 146 ILE A N     1 
ATOM   1127  C  CA    . ILE A 1 146 ? -47.100 -15.741 0.361    1.00 35.20  ? 146 ILE A CA    1 
ATOM   1128  C  C     . ILE A 1 146 ? -47.327 -15.150 -1.021   1.00 35.30  ? 146 ILE A C     1 
ATOM   1129  O  O     . ILE A 1 146 ? -48.468 -15.033 -1.483   1.00 37.01  ? 146 ILE A O     1 
ATOM   1130  C  CB    . ILE A 1 146 ? -46.170 -16.968 0.380    1.00 39.72  ? 146 ILE A CB    1 
ATOM   1131  C  CG1   . ILE A 1 146 ? -46.665 -18.085 -0.539   1.00 39.59  ? 146 ILE A CG1   1 
ATOM   1132  C  CG2   . ILE A 1 146 ? -45.998 -17.494 1.793    1.00 42.55  ? 146 ILE A CG2   1 
ATOM   1133  C  CD1   . ILE A 1 146 ? -45.639 -19.159 -0.748   1.00 45.49  ? 146 ILE A CD1   1 
ATOM   1134  N  N     . ASP A 1 147 ? -46.236 -14.721 -1.648   1.00 34.79  ? 147 ASP A N     1 
ATOM   1135  C  CA    . ASP A 1 147 ? -46.284 -14.131 -2.967   1.00 33.54  ? 147 ASP A CA    1 
ATOM   1136  C  C     . ASP A 1 147 ? -45.260 -14.879 -3.806   1.00 34.49  ? 147 ASP A C     1 
ATOM   1137  O  O     . ASP A 1 147 ? -44.075 -14.881 -3.474   1.00 40.04  ? 147 ASP A O     1 
ATOM   1138  C  CB    . ASP A 1 147 ? -46.009 -12.623 -2.883   1.00 37.66  ? 147 ASP A CB    1 
ATOM   1139  C  CG    . ASP A 1 147 ? -46.159 -11.937 -4.229   1.00 38.31  ? 147 ASP A CG    1 
ATOM   1140  O  OD1   . ASP A 1 147 ? -45.312 -12.198 -5.101   1.00 35.82  ? 147 ASP A OD1   1 
ATOM   1141  O  OD2   . ASP A 1 147 ? -47.148 -11.210 -4.407   1.00 41.89  ? 147 ASP A OD2   1 
ATOM   1142  N  N     . VAL A 1 148 ? -45.744 -15.563 -4.841   1.00 34.44  ? 148 VAL A N     1 
ATOM   1143  C  CA    . VAL A 1 148 ? -44.932 -16.519 -5.574   1.00 39.72  ? 148 VAL A CA    1 
ATOM   1144  C  C     . VAL A 1 148 ? -44.665 -15.994 -6.979   1.00 39.46  ? 148 VAL A C     1 
ATOM   1145  O  O     . VAL A 1 148 ? -45.527 -15.359 -7.597   1.00 40.13  ? 148 VAL A O     1 
ATOM   1146  C  CB    . VAL A 1 148 ? -45.614 -17.895 -5.671   1.00 38.78  ? 148 VAL A CB    1 
ATOM   1147  C  CG1   . VAL A 1 148 ? -45.772 -18.540 -4.309   1.00 43.42  ? 148 VAL A CG1   1 
ATOM   1148  C  CG2   . VAL A 1 148 ? -46.961 -17.797 -6.387   1.00 36.87  ? 148 VAL A CG2   1 
ATOM   1149  N  N     . PRO A 1 149 ? -43.477 -16.297 -7.533   1.00 39.95  ? 149 PRO A N     1 
ATOM   1150  C  CA    . PRO A 1 149 ? -43.217 -16.104 -8.956   1.00 45.03  ? 149 PRO A CA    1 
ATOM   1151  C  C     . PRO A 1 149 ? -43.896 -17.246 -9.696   1.00 48.52  ? 149 PRO A C     1 
ATOM   1152  O  O     . PRO A 1 149 ? -44.454 -18.136 -9.066   1.00 48.44  ? 149 PRO A O     1 
ATOM   1153  C  CB    . PRO A 1 149 ? -41.696 -16.175 -9.040   1.00 44.64  ? 149 PRO A CB    1 
ATOM   1154  C  CG    . PRO A 1 149 ? -41.307 -17.118 -7.912   1.00 41.71  ? 149 PRO A CG    1 
ATOM   1155  C  CD    . PRO A 1 149 ? -42.324 -16.869 -6.818   1.00 41.66  ? 149 PRO A CD    1 
ATOM   1156  N  N     . ASP A 1 150 ? -43.849 -17.219 -11.027  1.00 57.95  ? 150 ASP A N     1 
ATOM   1157  C  CA    . ASP A 1 150 ? -44.463 -18.273 -11.818  1.00 62.52  ? 150 ASP A CA    1 
ATOM   1158  C  C     . ASP A 1 150 ? -43.729 -19.600 -11.580  1.00 52.21  ? 150 ASP A C     1 
ATOM   1159  O  O     . ASP A 1 150 ? -44.339 -20.660 -11.635  1.00 59.48  ? 150 ASP A O     1 
ATOM   1160  C  CB    . ASP A 1 150 ? -44.560 -17.853 -13.287  1.00 68.00  ? 150 ASP A CB    1 
ATOM   1161  C  CG    . ASP A 1 150 ? -45.682 -16.873 -13.596  1.00 64.14  ? 150 ASP A CG    1 
ATOM   1162  O  OD1   . ASP A 1 150 ? -46.769 -17.004 -12.999  1.00 59.35  ? 150 ASP A OD1   1 
ATOM   1163  O  OD2   . ASP A 1 150 ? -45.472 -16.011 -14.465  1.00 76.12  ? 150 ASP A OD2   1 
ATOM   1164  N  N     . ASN A 1 151 ? -42.444 -19.536 -11.226  1.00 56.04  ? 151 ASN A N     1 
ATOM   1165  C  CA    . ASN A 1 151 ? -41.697 -20.715 -10.805  1.00 63.49  ? 151 ASN A CA    1 
ATOM   1166  C  C     . ASN A 1 151 ? -41.830 -20.972 -9.297   1.00 60.07  ? 151 ASN A C     1 
ATOM   1167  O  O     . ASN A 1 151 ? -41.087 -20.400 -8.501   1.00 65.21  ? 151 ASN A O     1 
ATOM   1168  C  CB    . ASN A 1 151 ? -40.210 -20.584 -11.148  1.00 59.24  ? 151 ASN A CB    1 
ATOM   1169  C  CG    . ASN A 1 151 ? -39.399 -21.792 -10.716  1.00 67.00  ? 151 ASN A CG    1 
ATOM   1170  O  OD1   . ASN A 1 151 ? -39.941 -22.793 -10.234  1.00 62.74  ? 151 ASN A OD1   1 
ATOM   1171  N  ND2   . ASN A 1 151 ? -38.090 -21.715 -10.902  1.00 69.82  ? 151 ASN A ND2   1 
ATOM   1172  N  N     . GLY A 1 152 ? -42.679 -21.933 -8.913   1.00 55.34  ? 152 GLY A N     1 
ATOM   1173  C  CA    . GLY A 1 152 ? -42.885 -22.279 -7.515   1.00 50.57  ? 152 GLY A CA    1 
ATOM   1174  C  C     . GLY A 1 152 ? -41.684 -22.951 -6.849   1.00 55.63  ? 152 GLY A C     1 
ATOM   1175  O  O     . GLY A 1 152 ? -41.615 -22.996 -5.613   1.00 52.84  ? 152 GLY A O     1 
ATOM   1176  N  N     . TRP A 1 153 ? -40.746 -23.490 -7.654   1.00 52.49  ? 153 TRP A N     1 
ATOM   1177  C  CA    . TRP A 1 153 ? -39.595 -24.179 -7.088   1.00 53.75  ? 153 TRP A CA    1 
ATOM   1178  C  C     . TRP A 1 153 ? -38.520 -23.199 -6.614   1.00 48.50  ? 153 TRP A C     1 
ATOM   1179  O  O     . TRP A 1 153 ? -37.561 -23.601 -5.966   1.00 51.98  ? 153 TRP A O     1 
ATOM   1180  C  CB    . TRP A 1 153 ? -39.020 -25.234 -8.057   1.00 57.74  ? 153 TRP A CB    1 
ATOM   1181  C  CG    . TRP A 1 153 ? -39.643 -26.597 -7.937   1.00 64.65  ? 153 TRP A CG    1 
ATOM   1182  C  CD1   . TRP A 1 153 ? -40.129 -27.361 -8.960   1.00 66.33  ? 153 TRP A CD1   1 
ATOM   1183  C  CD2   . TRP A 1 153 ? -39.867 -27.357 -6.729   1.00 69.29  ? 153 TRP A CD2   1 
ATOM   1184  N  NE1   . TRP A 1 153 ? -40.644 -28.531 -8.475   1.00 67.90  ? 153 TRP A NE1   1 
ATOM   1185  C  CE2   . TRP A 1 153 ? -40.492 -28.566 -7.112   1.00 70.24  ? 153 TRP A CE2   1 
ATOM   1186  C  CE3   . TRP A 1 153 ? -39.610 -27.140 -5.362   1.00 81.49  ? 153 TRP A CE3   1 
ATOM   1187  C  CZ2   . TRP A 1 153 ? -40.857 -29.550 -6.186   1.00 69.82  ? 153 TRP A CZ2   1 
ATOM   1188  C  CZ3   . TRP A 1 153 ? -39.975 -28.110 -4.446   1.00 83.74  ? 153 TRP A CZ3   1 
ATOM   1189  C  CH2   . TRP A 1 153 ? -40.593 -29.299 -4.857   1.00 78.08  ? 153 TRP A CH2   1 
ATOM   1190  N  N     . GLY A 1 154 ? -38.651 -21.911 -6.916   1.00 47.33  ? 154 GLY A N     1 
ATOM   1191  C  CA    . GLY A 1 154 ? -37.614 -20.965 -6.515   1.00 47.75  ? 154 GLY A CA    1 
ATOM   1192  C  C     . GLY A 1 154 ? -37.436 -20.827 -4.998   1.00 43.49  ? 154 GLY A C     1 
ATOM   1193  O  O     . GLY A 1 154 ? -38.199 -21.382 -4.205   1.00 47.27  ? 154 GLY A O     1 
ATOM   1194  N  N     . SER A 1 155 ? -36.376 -20.101 -4.621   1.00 40.28  ? 155 SER A N     1 
ATOM   1195  C  CA    . SER A 1 155 ? -36.081 -19.695 -3.254   1.00 39.05  ? 155 SER A CA    1 
ATOM   1196  C  C     . SER A 1 155 ? -36.743 -18.354 -2.932   1.00 40.39  ? 155 SER A C     1 
ATOM   1197  O  O     . SER A 1 155 ? -36.569 -17.381 -3.668   1.00 41.28  ? 155 SER A O     1 
ATOM   1198  C  CB    . SER A 1 155 ? -34.585 -19.566 -3.066   1.00 41.46  ? 155 SER A CB    1 
ATOM   1199  O  OG    . SER A 1 155 ? -34.277 -18.805 -1.901   1.00 42.16  ? 155 SER A OG    1 
ATOM   1200  N  N     . VAL A 1 156 ? -37.419 -18.299 -1.786   1.00 38.59  ? 156 VAL A N     1 
ATOM   1201  C  CA    . VAL A 1 156 ? -37.939 -17.061 -1.221   1.00 40.89  ? 156 VAL A CA    1 
ATOM   1202  C  C     . VAL A 1 156 ? -36.824 -16.019 -1.130   1.00 38.91  ? 156 VAL A C     1 
ATOM   1203  O  O     . VAL A 1 156 ? -37.051 -14.867 -1.499   1.00 39.73  ? 156 VAL A O     1 
ATOM   1204  C  CB    . VAL A 1 156 ? -38.598 -17.338 0.138    1.00 41.73  ? 156 VAL A CB    1 
ATOM   1205  C  CG1   . VAL A 1 156 ? -39.206 -16.098 0.780    1.00 46.21  ? 156 VAL A CG1   1 
ATOM   1206  C  CG2   . VAL A 1 156 ? -39.634 -18.439 0.007    1.00 46.02  ? 156 VAL A CG2   1 
ATOM   1207  N  N     . VAL A 1 157 ? -35.630 -16.443 -0.667   1.00 37.70  ? 157 VAL A N     1 
ATOM   1208  C  CA    . VAL A 1 157 ? -34.466 -15.583 -0.547   1.00 38.96  ? 157 VAL A CA    1 
ATOM   1209  C  C     . VAL A 1 157 ? -33.907 -15.231 -1.922   1.00 42.94  ? 157 VAL A C     1 
ATOM   1210  O  O     . VAL A 1 157 ? -33.785 -14.055 -2.281   1.00 41.12  ? 157 VAL A O     1 
ATOM   1211  C  CB    . VAL A 1 157 ? -33.371 -16.246 0.307    1.00 39.32  ? 157 VAL A CB    1 
ATOM   1212  C  CG1   . VAL A 1 157 ? -32.064 -15.458 0.291    1.00 37.65  ? 157 VAL A CG1   1 
ATOM   1213  C  CG2   . VAL A 1 157 ? -33.846 -16.440 1.729    1.00 41.13  ? 157 VAL A CG2   1 
ATOM   1214  N  N     . GLY A 1 158 ? -33.537 -16.271 -2.674   1.00 43.43  ? 158 GLY A N     1 
ATOM   1215  C  CA    . GLY A 1 158 ? -32.810 -16.099 -3.923   1.00 41.51  ? 158 GLY A CA    1 
ATOM   1216  C  C     . GLY A 1 158 ? -33.594 -15.237 -4.902   1.00 36.70  ? 158 GLY A C     1 
ATOM   1217  O  O     . GLY A 1 158 ? -33.062 -14.326 -5.558   1.00 34.30  ? 158 GLY A O     1 
ATOM   1218  N  N     . ASN A 1 159 ? -34.895 -15.517 -4.968   1.00 33.30  ? 159 ASN A N     1 
ATOM   1219  C  CA    . ASN A 1 159 ? -35.733 -14.765 -5.876   1.00 35.25  ? 159 ASN A CA    1 
ATOM   1220  C  C     . ASN A 1 159 ? -35.739 -13.287 -5.482   1.00 36.98  ? 159 ASN A C     1 
ATOM   1221  O  O     . ASN A 1 159 ? -35.583 -12.419 -6.334   1.00 37.50  ? 159 ASN A O     1 
ATOM   1222  C  CB    . ASN A 1 159 ? -37.132 -15.344 -5.927   1.00 38.10  ? 159 ASN A CB    1 
ATOM   1223  C  CG    . ASN A 1 159 ? -38.023 -14.510 -6.807   1.00 40.64  ? 159 ASN A CG    1 
ATOM   1224  O  OD1   . ASN A 1 159 ? -38.565 -13.495 -6.363   1.00 45.78  ? 159 ASN A OD1   1 
ATOM   1225  N  ND2   . ASN A 1 159 ? -38.118 -14.900 -8.063   1.00 38.40  ? 159 ASN A ND2   1 
ATOM   1226  N  N     . ALA A 1 160 ? -35.947 -13.006 -4.189   1.00 38.61  ? 160 ALA A N     1 
ATOM   1227  C  CA    . ALA A 1 160 ? -36.024 -11.633 -3.715   1.00 37.40  ? 160 ALA A CA    1 
ATOM   1228  C  C     . ALA A 1 160 ? -34.701 -10.915 -3.968   1.00 36.21  ? 160 ALA A C     1 
ATOM   1229  O  O     . ALA A 1 160 ? -34.677 -9.756  -4.382   1.00 34.52  ? 160 ALA A O     1 
ATOM   1230  C  CB    . ALA A 1 160 ? -36.398 -11.607 -2.247   1.00 36.86  ? 160 ALA A CB    1 
ATOM   1231  N  N     . LEU A 1 161 ? -33.578 -11.598 -3.744   1.00 39.59  ? 161 LEU A N     1 
ATOM   1232  C  CA    . LEU A 1 161 ? -32.293 -10.933 -3.916   1.00 38.71  ? 161 LEU A CA    1 
ATOM   1233  C  C     . LEU A 1 161 ? -32.045 -10.567 -5.371   1.00 38.80  ? 161 LEU A C     1 
ATOM   1234  O  O     . LEU A 1 161 ? -31.276 -9.652  -5.657   1.00 38.47  ? 161 LEU A O     1 
ATOM   1235  C  CB    . LEU A 1 161 ? -31.189 -11.819 -3.354   1.00 40.27  ? 161 LEU A CB    1 
ATOM   1236  C  CG    . LEU A 1 161 ? -31.215 -11.973 -1.832   1.00 40.86  ? 161 LEU A CG    1 
ATOM   1237  C  CD1   . LEU A 1 161 ? -30.119 -12.926 -1.396   1.00 44.47  ? 161 LEU A CD1   1 
ATOM   1238  C  CD2   . LEU A 1 161 ? -31.045 -10.621 -1.131   1.00 39.89  ? 161 LEU A CD2   1 
ATOM   1239  N  N     . ASP A 1 162 ? -32.727 -11.254 -6.291   1.00 39.96  ? 162 ASP A N     1 
ATOM   1240  C  CA    . ASP A 1 162 ? -32.590 -10.944 -7.704   1.00 41.39  ? 162 ASP A CA    1 
ATOM   1241  C  C     . ASP A 1 162 ? -33.676 -9.984  -8.202   1.00 35.77  ? 162 ASP A C     1 
ATOM   1242  O  O     . ASP A 1 162 ? -33.836 -9.825  -9.405   1.00 37.13  ? 162 ASP A O     1 
ATOM   1243  C  CB    . ASP A 1 162 ? -32.597 -12.230 -8.531   1.00 43.95  ? 162 ASP A CB    1 
ATOM   1244  C  CG    . ASP A 1 162 ? -31.689 -12.124 -9.743   1.00 50.24  ? 162 ASP A CG    1 
ATOM   1245  O  OD1   . ASP A 1 162 ? -30.584 -11.554 -9.584   1.00 52.78  ? 162 ASP A OD1   1 
ATOM   1246  O  OD2   . ASP A 1 162 ? -32.077 -12.646 -10.803  1.00 57.87  ? 162 ASP A OD2   1 
ATOM   1247  N  N     . HIS A 1 163 ? -34.426 -9.368  -7.283   1.00 36.10  ? 163 HIS A N     1 
ATOM   1248  C  CA    . HIS A 1 163 ? -35.448 -8.376  -7.587   1.00 35.63  ? 163 HIS A CA    1 
ATOM   1249  C  C     . HIS A 1 163 ? -36.591 -9.060  -8.319   1.00 40.17  ? 163 HIS A C     1 
ATOM   1250  O  O     . HIS A 1 163 ? -37.229 -8.480  -9.200   1.00 35.78  ? 163 HIS A O     1 
ATOM   1251  C  CB    . HIS A 1 163 ? -34.896 -7.164  -8.349   1.00 38.06  ? 163 HIS A CB    1 
ATOM   1252  C  CG    . HIS A 1 163 ? -33.799 -6.440  -7.653   1.00 38.28  ? 163 HIS A CG    1 
ATOM   1253  N  ND1   . HIS A 1 163 ? -32.987 -5.513  -8.267   1.00 38.27  ? 163 HIS A ND1   1 
ATOM   1254  C  CD2   . HIS A 1 163 ? -33.393 -6.506  -6.376   1.00 37.19  ? 163 HIS A CD2   1 
ATOM   1255  C  CE1   . HIS A 1 163 ? -32.093 -5.089  -7.385   1.00 35.75  ? 163 HIS A CE1   1 
ATOM   1256  N  NE2   . HIS A 1 163 ? -32.354 -5.647  -6.229   1.00 36.59  ? 163 HIS A NE2   1 
ATOM   1257  N  N     . GLY A 1 164 ? -36.869 -10.305 -7.919   1.00 36.14  ? 164 GLY A N     1 
ATOM   1258  C  CA    . GLY A 1 164 ? -37.951 -11.034 -8.544   1.00 37.36  ? 164 GLY A CA    1 
ATOM   1259  C  C     . GLY A 1 164 ? -39.304 -10.487 -8.104   1.00 37.52  ? 164 GLY A C     1 
ATOM   1260  O  O     . GLY A 1 164 ? -39.382 -9.675  -7.189   1.00 41.14  ? 164 GLY A O     1 
ATOM   1261  N  N     . ILE A 1 165 ? -40.355 -10.938 -8.782   1.00 39.88  ? 165 ILE A N     1 
ATOM   1262  C  CA    . ILE A 1 165 ? -41.693 -10.410 -8.605   1.00 40.32  ? 165 ILE A CA    1 
ATOM   1263  C  C     . ILE A 1 165 ? -42.709 -11.549 -8.547   1.00 43.55  ? 165 ILE A C     1 
ATOM   1264  O  O     . ILE A 1 165 ? -42.451 -12.671 -8.984   1.00 40.32  ? 165 ILE A O     1 
ATOM   1265  C  CB    . ILE A 1 165 ? -42.051 -9.448  -9.748   1.00 46.18  ? 165 ILE A CB    1 
ATOM   1266  C  CG1   . ILE A 1 165 ? -42.115 -10.206 -11.080  1.00 53.62  ? 165 ILE A CG1   1 
ATOM   1267  C  CG2   . ILE A 1 165 ? -41.090 -8.259  -9.769   1.00 44.34  ? 165 ILE A CG2   1 
ATOM   1268  C  CD1   . ILE A 1 165 ? -42.733 -9.417  -12.218  1.00 67.70  ? 165 ILE A CD1   1 
ATOM   1269  N  N     . GLY A 1 166 ? -43.901 -11.196 -8.061   1.00 40.28  ? 166 GLY A N     1 
ATOM   1270  C  CA    . GLY A 1 166 ? -45.057 -12.051 -8.125   1.00 38.36  ? 166 GLY A CA    1 
ATOM   1271  C  C     . GLY A 1 166 ? -46.298 -11.216 -8.382   1.00 36.03  ? 166 GLY A C     1 
ATOM   1272  O  O     . GLY A 1 166 ? -46.208 -10.153 -8.958   1.00 40.31  ? 166 GLY A O     1 
ATOM   1273  N  N     . TYR A 1 167 ? -47.452 -11.727 -7.961   1.00 37.92  ? 167 TYR A N     1 
ATOM   1274  C  CA    . TYR A 1 167 ? -48.710 -11.323 -8.541   1.00 34.11  ? 167 TYR A CA    1 
ATOM   1275  C  C     . TYR A 1 167 ? -49.737 -11.029 -7.467   1.00 34.00  ? 167 TYR A C     1 
ATOM   1276  O  O     . TYR A 1 167 ? -50.921 -10.913 -7.791   1.00 35.20  ? 167 TYR A O     1 
ATOM   1277  C  CB    . TYR A 1 167 ? -49.165 -12.421 -9.509   1.00 40.50  ? 167 TYR A CB    1 
ATOM   1278  C  CG    . TYR A 1 167 ? -48.131 -12.638 -10.576  1.00 41.27  ? 167 TYR A CG    1 
ATOM   1279  C  CD1   . TYR A 1 167 ? -47.962 -11.707 -11.592  1.00 47.26  ? 167 TYR A CD1   1 
ATOM   1280  C  CD2   . TYR A 1 167 ? -47.202 -13.662 -10.462  1.00 40.40  ? 167 TYR A CD2   1 
ATOM   1281  C  CE1   . TYR A 1 167 ? -46.950 -11.844 -12.532  1.00 53.58  ? 167 TYR A CE1   1 
ATOM   1282  C  CE2   . TYR A 1 167 ? -46.185 -13.812 -11.390  1.00 50.09  ? 167 TYR A CE2   1 
ATOM   1283  C  CZ    . TYR A 1 167 ? -46.055 -12.900 -12.425  1.00 56.53  ? 167 TYR A CZ    1 
ATOM   1284  O  OH    . TYR A 1 167 ? -45.034 -13.061 -13.336  1.00 68.24  ? 167 TYR A OH    1 
ATOM   1285  N  N     . THR A 1 168 ? -49.284 -10.883 -6.210   1.00 35.86  ? 168 THR A N     1 
ATOM   1286  C  CA    . THR A 1 168 ? -50.157 -10.343 -5.174   1.00 35.74  ? 168 THR A CA    1 
ATOM   1287  C  C     . THR A 1 168 ? -49.768 -8.896  -4.881   1.00 35.90  ? 168 THR A C     1 
ATOM   1288  O  O     . THR A 1 168 ? -48.803 -8.364  -5.461   1.00 36.67  ? 168 THR A O     1 
ATOM   1289  C  CB    . THR A 1 168 ? -50.157 -11.237 -3.929   1.00 36.76  ? 168 THR A CB    1 
ATOM   1290  O  OG1   . THR A 1 168 ? -49.083 -10.889 -3.046   1.00 41.02  ? 168 THR A OG1   1 
ATOM   1291  C  CG2   . THR A 1 168 ? -50.119 -12.710 -4.305   1.00 36.98  ? 168 THR A CG2   1 
ATOM   1292  N  N     . PRO A 1 169 ? -50.480 -8.217  -3.955   1.00 38.23  ? 169 PRO A N     1 
ATOM   1293  C  CA    . PRO A 1 169 ? -50.069 -6.882  -3.513   1.00 36.32  ? 169 PRO A CA    1 
ATOM   1294  C  C     . PRO A 1 169 ? -48.643 -6.878  -2.982   1.00 40.24  ? 169 PRO A C     1 
ATOM   1295  O  O     . PRO A 1 169 ? -47.982 -5.841  -3.047   1.00 33.08  ? 169 PRO A O     1 
ATOM   1296  C  CB    . PRO A 1 169 ? -51.127 -6.515  -2.467   1.00 37.81  ? 169 PRO A CB    1 
ATOM   1297  C  CG    . PRO A 1 169 ? -52.340 -7.301  -2.914   1.00 38.74  ? 169 PRO A CG    1 
ATOM   1298  C  CD    . PRO A 1 169 ? -51.763 -8.628  -3.361   1.00 37.74  ? 169 PRO A CD    1 
ATOM   1299  N  N     . TYR A 1 170 ? -48.150 -8.056  -2.549   1.00 33.00  ? 170 TYR A N     1 
ATOM   1300  C  CA    . TYR A 1 170 ? -46.797 -8.176  -2.059   1.00 32.84  ? 170 TYR A CA    1 
ATOM   1301  C  C     . TYR A 1 170 ? -45.848 -8.616  -3.171   1.00 34.83  ? 170 TYR A C     1 
ATOM   1302  O  O     . TYR A 1 170 ? -44.841 -9.260  -2.884   1.00 36.09  ? 170 TYR A O     1 
ATOM   1303  C  CB    . TYR A 1 170 ? -46.739 -9.132  -0.869   1.00 31.52  ? 170 TYR A CB    1 
ATOM   1304  C  CG    . TYR A 1 170 ? -47.154 -8.573  0.469    1.00 28.48  ? 170 TYR A CG    1 
ATOM   1305  C  CD1   . TYR A 1 170 ? -48.350 -7.889  0.654    1.00 35.70  ? 170 TYR A CD1   1 
ATOM   1306  C  CD2   . TYR A 1 170 ? -46.384 -8.799  1.586    1.00 34.33  ? 170 TYR A CD2   1 
ATOM   1307  C  CE1   . TYR A 1 170 ? -48.736 -7.417  1.905    1.00 34.39  ? 170 TYR A CE1   1 
ATOM   1308  C  CE2   . TYR A 1 170 ? -46.760 -8.349  2.843    1.00 35.20  ? 170 TYR A CE2   1 
ATOM   1309  C  CZ    . TYR A 1 170 ? -47.931 -7.631  3.007    1.00 34.12  ? 170 TYR A CZ    1 
ATOM   1310  O  OH    . TYR A 1 170 ? -48.272 -7.208  4.277    1.00 34.79  ? 170 TYR A OH    1 
ATOM   1311  N  N     . GLY A 1 171 ? -46.129 -8.195  -4.415   1.00 37.70  ? 171 GLY A N     1 
ATOM   1312  C  CA    . GLY A 1 171 ? -45.443 -8.649  -5.622   1.00 33.42  ? 171 GLY A CA    1 
ATOM   1313  C  C     . GLY A 1 171 ? -43.974 -8.243  -5.783   1.00 39.73  ? 171 GLY A C     1 
ATOM   1314  O  O     . GLY A 1 171 ? -43.252 -8.909  -6.518   1.00 35.90  ? 171 GLY A O     1 
ATOM   1315  N  N     . ASP A 1 172 ? -43.540 -7.123  -5.182   1.00 39.18  ? 172 ASP A N     1 
ATOM   1316  C  CA    . ASP A 1 172 ? -42.144 -6.703  -5.240   1.00 36.27  ? 172 ASP A CA    1 
ATOM   1317  C  C     . ASP A 1 172 ? -41.407 -7.368  -4.080   1.00 37.24  ? 172 ASP A C     1 
ATOM   1318  O  O     . ASP A 1 172 ? -41.374 -6.863  -2.951   1.00 34.30  ? 172 ASP A O     1 
ATOM   1319  C  CB    . ASP A 1 172 ? -42.046 -5.166  -5.236   1.00 40.15  ? 172 ASP A CB    1 
ATOM   1320  C  CG    . ASP A 1 172 ? -40.645 -4.552  -5.301   1.00 43.60  ? 172 ASP A CG    1 
ATOM   1321  O  OD1   . ASP A 1 172 ? -39.636 -5.280  -5.104   1.00 41.01  ? 172 ASP A OD1   1 
ATOM   1322  O  OD2   . ASP A 1 172 ? -40.568 -3.342  -5.591   1.00 46.48  ? 172 ASP A OD2   1 
ATOM   1323  N  N     . HIS A 1 173 ? -40.815 -8.531  -4.364   1.00 36.55  ? 173 HIS A N     1 
ATOM   1324  C  CA    . HIS A 1 173 ? -40.293 -9.388  -3.323   1.00 33.47  ? 173 HIS A CA    1 
ATOM   1325  C  C     . HIS A 1 173 ? -39.222 -8.677  -2.493   1.00 33.55  ? 173 HIS A C     1 
ATOM   1326  O  O     . HIS A 1 173 ? -39.234 -8.798  -1.275   1.00 33.33  ? 173 HIS A O     1 
ATOM   1327  C  CB    . HIS A 1 173 ? -39.764 -10.692 -3.927   1.00 34.81  ? 173 HIS A CB    1 
ATOM   1328  C  CG    . HIS A 1 173 ? -40.853 -11.497 -4.535   1.00 31.79  ? 173 HIS A CG    1 
ATOM   1329  N  ND1   . HIS A 1 173 ? -40.617 -12.669 -5.204   1.00 35.16  ? 173 HIS A ND1   1 
ATOM   1330  C  CD2   . HIS A 1 173 ? -42.169 -11.322 -4.553   1.00 38.62  ? 173 HIS A CD2   1 
ATOM   1331  C  CE1   . HIS A 1 173 ? -41.779 -13.205 -5.583   1.00 35.86  ? 173 HIS A CE1   1 
ATOM   1332  N  NE2   . HIS A 1 173 ? -42.743 -12.395 -5.196   1.00 37.64  ? 173 HIS A NE2   1 
ATOM   1333  N  N     . PHE A 1 174 ? -38.279 -7.970  -3.120   1.00 32.12  ? 174 PHE A N     1 
ATOM   1334  C  CA    . PHE A 1 174 ? -37.202 -7.374  -2.340   1.00 37.63  ? 174 PHE A CA    1 
ATOM   1335  C  C     . PHE A 1 174 ? -37.737 -6.199  -1.515   1.00 37.17  ? 174 PHE A C     1 
ATOM   1336  O  O     . PHE A 1 174 ? -37.241 -5.950  -0.425   1.00 37.65  ? 174 PHE A O     1 
ATOM   1337  C  CB    . PHE A 1 174 ? -35.987 -6.951  -3.175   1.00 33.74  ? 174 PHE A CB    1 
ATOM   1338  C  CG    . PHE A 1 174 ? -34.782 -6.633  -2.318   1.00 34.46  ? 174 PHE A CG    1 
ATOM   1339  C  CD1   . PHE A 1 174 ? -34.144 -7.623  -1.599   1.00 34.84  ? 174 PHE A CD1   1 
ATOM   1340  C  CD2   . PHE A 1 174 ? -34.381 -5.325  -2.117   1.00 37.50  ? 174 PHE A CD2   1 
ATOM   1341  C  CE1   . PHE A 1 174 ? -33.076 -7.321  -0.767   1.00 37.92  ? 174 PHE A CE1   1 
ATOM   1342  C  CE2   . PHE A 1 174 ? -33.323 -5.019  -1.279   1.00 37.29  ? 174 PHE A CE2   1 
ATOM   1343  C  CZ    . PHE A 1 174 ? -32.672 -6.016  -0.606   1.00 40.64  ? 174 PHE A CZ    1 
ATOM   1344  N  N     . ALA A 1 175 ? -38.798 -5.529  -1.980   1.00 39.76  ? 175 ALA A N     1 
ATOM   1345  C  CA    . ALA A 1 175 ? -39.428 -4.485  -1.166   1.00 39.33  ? 175 ALA A CA    1 
ATOM   1346  C  C     . ALA A 1 175 ? -39.981 -5.058  0.135    1.00 35.41  ? 175 ALA A C     1 
ATOM   1347  O  O     . ALA A 1 175 ? -40.038 -4.347  1.127    1.00 35.97  ? 175 ALA A O     1 
ATOM   1348  C  CB    . ALA A 1 175 ? -40.510 -3.765  -1.941   1.00 38.52  ? 175 ALA A CB    1 
ATOM   1349  N  N     . MET A 1 176 ? -40.368 -6.348  0.150    1.00 37.24  ? 176 MET A N     1 
ATOM   1350  C  CA    . MET A 1 176 ? -40.989 -6.922  1.332    1.00 34.57  ? 176 MET A CA    1 
ATOM   1351  C  C     . MET A 1 176 ? -39.938 -7.565  2.230    1.00 37.89  ? 176 MET A C     1 
ATOM   1352  O  O     . MET A 1 176 ? -40.264 -8.127  3.294    1.00 36.62  ? 176 MET A O     1 
ATOM   1353  C  CB    . MET A 1 176 ? -42.041 -7.955  0.957    1.00 38.19  ? 176 MET A CB    1 
ATOM   1354  C  CG    . MET A 1 176 ? -43.193 -7.383  0.139    1.00 37.25  ? 176 MET A CG    1 
ATOM   1355  S  SD    . MET A 1 176 ? -44.201 -6.172  1.008    1.00 41.16  ? 176 MET A SD    1 
ATOM   1356  C  CE    . MET A 1 176 ? -43.507 -4.625  0.426    1.00 39.81  ? 176 MET A CE    1 
ATOM   1357  N  N     . GLN A 1 177 ? -38.675 -7.493  1.782    1.00 34.75  ? 177 GLN A N     1 
ATOM   1358  C  CA    . GLN A 1 177 ? -37.568 -8.044  2.549    1.00 33.75  ? 177 GLN A CA    1 
ATOM   1359  C  C     . GLN A 1 177 ? -37.394 -7.202  3.803    1.00 34.65  ? 177 GLN A C     1 
ATOM   1360  O  O     . GLN A 1 177 ? -37.532 -5.983  3.772    1.00 35.94  ? 177 GLN A O     1 
ATOM   1361  C  CB    . GLN A 1 177 ? -36.278 -8.078  1.720    1.00 33.50  ? 177 GLN A CB    1 
ATOM   1362  C  CG    . GLN A 1 177 ? -35.068 -8.608  2.472    1.00 36.50  ? 177 GLN A CG    1 
ATOM   1363  C  CD    . GLN A 1 177 ? -34.250 -7.498  3.067    1.00 36.59  ? 177 GLN A CD    1 
ATOM   1364  O  OE1   . GLN A 1 177 ? -34.286 -6.367  2.594    1.00 41.63  ? 177 GLN A OE1   1 
ATOM   1365  N  NE2   . GLN A 1 177 ? -33.508 -7.808  4.110    1.00 37.77  ? 177 GLN A NE2   1 
ATOM   1366  N  N     . CYS A 1 178 ? -37.076 -7.852  4.921    1.00 36.66  ? 178 CYS A N     1 
ATOM   1367  C  CA    . CYS A 1 178 ? -36.853 -7.115  6.157    1.00 37.31  ? 178 CYS A CA    1 
ATOM   1368  C  C     . CYS A 1 178 ? -35.872 -7.872  7.045    1.00 37.49  ? 178 CYS A C     1 
ATOM   1369  O  O     . CYS A 1 178 ? -36.203 -8.929  7.602    1.00 35.02  ? 178 CYS A O     1 
ATOM   1370  C  CB    . CYS A 1 178 ? -38.166 -6.860  6.883    1.00 37.67  ? 178 CYS A CB    1 
ATOM   1371  S  SG    . CYS A 1 178 ? -37.970 -5.665  8.222    1.00 37.28  ? 178 CYS A SG    1 
ATOM   1372  N  N     . GLY A 1 179 ? -34.660 -7.327  7.101    1.00 33.44  ? 179 GLY A N     1 
ATOM   1373  C  CA    . GLY A 1 179 ? -33.560 -7.900  7.851    1.00 38.42  ? 179 GLY A CA    1 
ATOM   1374  C  C     . GLY A 1 179 ? -32.885 -9.052  7.109    1.00 35.71  ? 179 GLY A C     1 
ATOM   1375  O  O     . GLY A 1 179 ? -33.567 -9.838  6.448    1.00 38.82  ? 179 GLY A O     1 
ATOM   1376  N  N     . MET A 1 180 ? -31.545 -9.131  7.224    1.00 35.89  ? 180 MET A N     1 
ATOM   1377  C  CA    . MET A 1 180 ? -30.807 -10.251 6.655    1.00 38.02  ? 180 MET A CA    1 
ATOM   1378  C  C     . MET A 1 180 ? -29.518 -10.496 7.445    1.00 37.99  ? 180 MET A C     1 
ATOM   1379  O  O     . MET A 1 180 ? -28.973 -9.609  8.113    1.00 36.90  ? 180 MET A O     1 
ATOM   1380  C  CB    . MET A 1 180 ? -30.498 -10.050 5.167    1.00 36.41  ? 180 MET A CB    1 
ATOM   1381  C  CG    . MET A 1 180 ? -29.633 -8.841  4.872    1.00 37.76  ? 180 MET A CG    1 
ATOM   1382  S  SD    . MET A 1 180 ? -29.074 -8.701  3.161    1.00 40.01  ? 180 MET A SD    1 
ATOM   1383  C  CE    . MET A 1 180 ? -30.646 -8.680  2.293    1.00 36.78  ? 180 MET A CE    1 
ATOM   1384  N  N     . GLU A 1 181 ? -29.085 -11.755 7.406    1.00 34.69  ? 181 GLU A N     1 
ATOM   1385  C  CA    . GLU A 1 181 ? -27.758 -12.124 7.855    1.00 35.00  ? 181 GLU A CA    1 
ATOM   1386  C  C     . GLU A 1 181 ? -26.900 -12.375 6.629    1.00 35.79  ? 181 GLU A C     1 
ATOM   1387  O  O     . GLU A 1 181 ? -27.337 -13.045 5.692    1.00 36.37  ? 181 GLU A O     1 
ATOM   1388  C  CB    . GLU A 1 181 ? -27.789 -13.372 8.723    1.00 37.34  ? 181 GLU A CB    1 
ATOM   1389  C  CG    . GLU A 1 181 ? -26.442 -13.699 9.362    1.00 40.85  ? 181 GLU A CG    1 
ATOM   1390  C  CD    . GLU A 1 181 ? -26.530 -14.896 10.302   1.00 44.72  ? 181 GLU A CD    1 
ATOM   1391  O  OE1   . GLU A 1 181 ? -26.494 -14.673 11.536   1.00 42.62  ? 181 GLU A OE1   1 
ATOM   1392  O  OE2   . GLU A 1 181 ? -26.700 -16.041 9.795    1.00 44.55  ? 181 GLU A OE2   1 
ATOM   1393  N  N     . VAL A 1 182 ? -25.681 -11.833 6.673    1.00 36.43  ? 182 VAL A N     1 
ATOM   1394  C  CA    . VAL A 1 182 ? -24.777 -11.879 5.549    1.00 38.89  ? 182 VAL A CA    1 
ATOM   1395  C  C     . VAL A 1 182 ? -23.393 -12.292 6.017    1.00 41.28  ? 182 VAL A C     1 
ATOM   1396  O  O     . VAL A 1 182 ? -22.855 -11.729 6.972    1.00 37.20  ? 182 VAL A O     1 
ATOM   1397  C  CB    . VAL A 1 182 ? -24.692 -10.510 4.854    1.00 45.91  ? 182 VAL A CB    1 
ATOM   1398  C  CG1   . VAL A 1 182 ? -23.844 -10.616 3.599    1.00 45.15  ? 182 VAL A CG1   1 
ATOM   1399  C  CG2   . VAL A 1 182 ? -26.074 -9.960  4.556    1.00 47.49  ? 182 VAL A CG2   1 
ATOM   1400  N  N     . VAL A 1 183 ? -22.832 -13.258 5.289    1.00 39.25  ? 183 VAL A N     1 
ATOM   1401  C  CA    . VAL A 1 183 ? -21.416 -13.559 5.342    1.00 40.69  ? 183 VAL A CA    1 
ATOM   1402  C  C     . VAL A 1 183 ? -20.722 -12.716 4.270    1.00 36.51  ? 183 VAL A C     1 
ATOM   1403  O  O     . VAL A 1 183 ? -20.969 -12.863 3.082    1.00 46.18  ? 183 VAL A O     1 
ATOM   1404  C  CB    . VAL A 1 183 ? -21.187 -15.071 5.124    1.00 39.73  ? 183 VAL A CB    1 
ATOM   1405  C  CG1   . VAL A 1 183 ? -19.708 -15.394 5.026    1.00 40.00  ? 183 VAL A CG1   1 
ATOM   1406  C  CG2   . VAL A 1 183 ? -21.870 -15.904 6.205    1.00 37.96  ? 183 VAL A CG2   1 
ATOM   1407  N  N     . LEU A 1 184 ? -19.874 -11.814 4.718    1.00 37.30  ? 184 LEU A N     1 
ATOM   1408  C  CA    . LEU A 1 184 ? -19.133 -10.928 3.857    1.00 43.12  ? 184 LEU A CA    1 
ATOM   1409  C  C     . LEU A 1 184 ? -18.028 -11.713 3.157    1.00 43.42  ? 184 LEU A C     1 
ATOM   1410  O  O     . LEU A 1 184 ? -17.710 -12.837 3.542    1.00 40.08  ? 184 LEU A O     1 
ATOM   1411  C  CB    . LEU A 1 184 ? -18.553 -9.807  4.727    1.00 48.72  ? 184 LEU A CB    1 
ATOM   1412  C  CG    . LEU A 1 184 ? -19.585 -8.937  5.440    1.00 48.85  ? 184 LEU A CG    1 
ATOM   1413  C  CD1   . LEU A 1 184 ? -18.929 -7.771  6.177    1.00 45.81  ? 184 LEU A CD1   1 
ATOM   1414  C  CD2   . LEU A 1 184 ? -20.613 -8.422  4.444    1.00 53.33  ? 184 LEU A CD2   1 
ATOM   1415  N  N     . PRO A 1 185 ? -17.451 -11.158 2.071    1.00 42.76  ? 185 PRO A N     1 
ATOM   1416  C  CA    . PRO A 1 185 ? -16.466 -11.879 1.270    1.00 44.66  ? 185 PRO A CA    1 
ATOM   1417  C  C     . PRO A 1 185 ? -15.146 -12.157 1.980    1.00 49.39  ? 185 PRO A C     1 
ATOM   1418  O  O     . PRO A 1 185 ? -14.330 -12.914 1.455    1.00 53.54  ? 185 PRO A O     1 
ATOM   1419  C  CB    . PRO A 1 185 ? -16.185 -10.948 0.082    1.00 43.72  ? 185 PRO A CB    1 
ATOM   1420  C  CG    . PRO A 1 185 ? -17.368 -9.993  0.055    1.00 41.98  ? 185 PRO A CG    1 
ATOM   1421  C  CD    . PRO A 1 185 ? -17.770 -9.841  1.502    1.00 40.81  ? 185 PRO A CD    1 
ATOM   1422  N  N     . ASN A 1 186 ? -14.947 -11.546 3.151    1.00 45.21  ? 186 ASN A N     1 
ATOM   1423  C  CA    . ASN A 1 186 ? -13.793 -11.834 3.990    1.00 51.10  ? 186 ASN A CA    1 
ATOM   1424  C  C     . ASN A 1 186 ? -14.124 -12.886 5.039    1.00 50.46  ? 186 ASN A C     1 
ATOM   1425  O  O     . ASN A 1 186 ? -13.281 -13.159 5.875    1.00 57.51  ? 186 ASN A O     1 
ATOM   1426  C  CB    . ASN A 1 186 ? -13.276 -10.603 4.740    1.00 51.27  ? 186 ASN A CB    1 
ATOM   1427  C  CG    . ASN A 1 186 ? -14.317 -10.009 5.666    1.00 57.29  ? 186 ASN A CG    1 
ATOM   1428  O  OD1   . ASN A 1 186 ? -15.394 -10.575 5.861    1.00 46.80  ? 186 ASN A OD1   1 
ATOM   1429  N  ND2   . ASN A 1 186 ? -14.025 -8.840  6.209    1.00 60.14  ? 186 ASN A ND2   1 
ATOM   1430  N  N     . GLY A 1 187 ? -15.359 -13.395 5.072    1.00 41.45  ? 187 GLY A N     1 
ATOM   1431  C  CA    . GLY A 1 187 ? -15.700 -14.421 6.041    1.00 43.98  ? 187 GLY A CA    1 
ATOM   1432  C  C     . GLY A 1 187 ? -16.349 -13.901 7.325    1.00 42.70  ? 187 GLY A C     1 
ATOM   1433  O  O     . GLY A 1 187 ? -16.809 -14.720 8.120    1.00 38.61  ? 187 GLY A O     1 
ATOM   1434  N  N     . GLU A 1 188 ? -16.443 -12.566 7.495    1.00 38.09  ? 188 GLU A N     1 
ATOM   1435  C  CA    . GLU A 1 188 ? -17.120 -11.971 8.643    1.00 41.50  ? 188 GLU A CA    1 
ATOM   1436  C  C     . GLU A 1 188 ? -18.638 -12.078 8.467    1.00 40.61  ? 188 GLU A C     1 
ATOM   1437  O  O     . GLU A 1 188 ? -19.131 -11.980 7.357    1.00 41.30  ? 188 GLU A O     1 
ATOM   1438  C  CB    . GLU A 1 188 ? -16.809 -10.478 8.799    1.00 42.92  ? 188 GLU A CB    1 
ATOM   1439  C  CG    . GLU A 1 188 ? -15.366 -10.159 9.123    1.00 45.76  ? 188 GLU A CG    1 
ATOM   1440  C  CD    . GLU A 1 188 ? -14.862 -10.861 10.372   1.00 47.71  ? 188 GLU A CD    1 
ATOM   1441  O  OE1   . GLU A 1 188 ? -15.281 -10.482 11.469   1.00 49.94  ? 188 GLU A OE1   1 
ATOM   1442  O  OE2   . GLU A 1 188 ? -14.111 -11.826 10.235   1.00 49.21  ? 188 GLU A OE2   1 
ATOM   1443  N  N     . VAL A 1 189 ? -19.380 -12.212 9.575    1.00 37.01  ? 189 VAL A N     1 
ATOM   1444  C  CA    . VAL A 1 189 ? -20.832 -12.297 9.521    1.00 37.21  ? 189 VAL A CA    1 
ATOM   1445  C  C     . VAL A 1 189 ? -21.439 -11.029 10.126   1.00 36.25  ? 189 VAL A C     1 
ATOM   1446  O  O     . VAL A 1 189 ? -20.958 -10.537 11.138   1.00 39.41  ? 189 VAL A O     1 
ATOM   1447  C  CB    . VAL A 1 189 ? -21.345 -13.560 10.223   1.00 36.80  ? 189 VAL A CB    1 
ATOM   1448  C  CG1   . VAL A 1 189 ? -20.991 -13.578 11.698   1.00 40.35  ? 189 VAL A CG1   1 
ATOM   1449  C  CG2   . VAL A 1 189 ? -22.837 -13.724 10.021   1.00 35.73  ? 189 VAL A CG2   1 
ATOM   1450  N  N     . VAL A 1 190 ? -22.442 -10.463 9.446    1.00 39.54  ? 190 VAL A N     1 
ATOM   1451  C  CA    . VAL A 1 190 ? -23.118 -9.251  9.889    1.00 40.04  ? 190 VAL A CA    1 
ATOM   1452  C  C     . VAL A 1 190 ? -24.613 -9.480  9.770    1.00 39.51  ? 190 VAL A C     1 
ATOM   1453  O  O     . VAL A 1 190 ? -25.073 -10.261 8.924    1.00 41.08  ? 190 VAL A O     1 
ATOM   1454  C  CB    . VAL A 1 190 ? -22.745 -8.007  9.062    1.00 46.04  ? 190 VAL A CB    1 
ATOM   1455  C  CG1   . VAL A 1 190 ? -21.316 -7.570  9.295    1.00 50.38  ? 190 VAL A CG1   1 
ATOM   1456  C  CG2   . VAL A 1 190 ? -22.988 -8.240  7.579    1.00 48.15  ? 190 VAL A CG2   1 
ATOM   1457  N  N     . ARG A 1 191 ? -25.344 -8.699  10.562   1.00 35.60  ? 191 ARG A N     1 
ATOM   1458  C  CA    . ARG A 1 191 ? -26.786 -8.638  10.489   1.00 33.58  ? 191 ARG A CA    1 
ATOM   1459  C  C     . ARG A 1 191 ? -27.211 -7.197  10.280   1.00 38.61  ? 191 ARG A C     1 
ATOM   1460  O  O     . ARG A 1 191 ? -26.695 -6.282  10.914   1.00 38.03  ? 191 ARG A O     1 
ATOM   1461  C  CB    . ARG A 1 191 ? -27.407 -9.239  11.737   1.00 32.05  ? 191 ARG A CB    1 
ATOM   1462  C  CG    . ARG A 1 191 ? -27.182 -10.733 11.838   1.00 36.27  ? 191 ARG A CG    1 
ATOM   1463  C  CD    . ARG A 1 191 ? -27.795 -11.312 13.092   1.00 38.98  ? 191 ARG A CD    1 
ATOM   1464  N  NE    . ARG A 1 191 ? -27.698 -12.759 13.088   1.00 38.06  ? 191 ARG A NE    1 
ATOM   1465  C  CZ    . ARG A 1 191 ? -28.301 -13.563 13.945   1.00 39.45  ? 191 ARG A CZ    1 
ATOM   1466  N  NH1   . ARG A 1 191 ? -29.075 -13.070 14.895   1.00 40.44  ? 191 ARG A NH1   1 
ATOM   1467  N  NH2   . ARG A 1 191 ? -28.153 -14.869 13.810   1.00 40.81  ? 191 ARG A NH2   1 
ATOM   1468  N  N     . THR A 1 192 ? -28.158 -7.017  9.361    1.00 40.44  ? 192 THR A N     1 
ATOM   1469  C  CA    . THR A 1 192 ? -28.611 -5.696  8.989    1.00 39.08  ? 192 THR A CA    1 
ATOM   1470  C  C     . THR A 1 192 ? -29.785 -5.299  9.876    1.00 41.16  ? 192 THR A C     1 
ATOM   1471  O  O     . THR A 1 192 ? -30.395 -6.153  10.525   1.00 37.08  ? 192 THR A O     1 
ATOM   1472  C  CB    . THR A 1 192 ? -29.002 -5.664  7.510    1.00 37.55  ? 192 THR A CB    1 
ATOM   1473  O  OG1   . THR A 1 192 ? -30.178 -6.457  7.399    1.00 36.03  ? 192 THR A OG1   1 
ATOM   1474  C  CG2   . THR A 1 192 ? -27.902 -6.184  6.616    1.00 40.92  ? 192 THR A CG2   1 
ATOM   1475  N  N     . GLY A 1 193 ? -30.088 -3.987  9.858    1.00 35.52  ? 193 GLY A N     1 
ATOM   1476  C  CA    . GLY A 1 193 ? -31.276 -3.457  10.499   1.00 34.88  ? 193 GLY A CA    1 
ATOM   1477  C  C     . GLY A 1 193 ? -31.215 -3.669  12.010   1.00 35.86  ? 193 GLY A C     1 
ATOM   1478  O  O     . GLY A 1 193 ? -30.174 -3.509  12.653   1.00 35.91  ? 193 GLY A O     1 
ATOM   1479  N  N     . MET A 1 194 ? -32.366 -4.028  12.562   1.00 37.00  ? 194 MET A N     1 
ATOM   1480  C  CA    . MET A 1 194 ? -32.512 -4.256  13.982   1.00 38.05  ? 194 MET A CA    1 
ATOM   1481  C  C     . MET A 1 194 ? -31.794 -5.542  14.401   1.00 40.78  ? 194 MET A C     1 
ATOM   1482  O  O     . MET A 1 194 ? -31.522 -5.734  15.579   1.00 36.42  ? 194 MET A O     1 
ATOM   1483  C  CB    . MET A 1 194 ? -33.996 -4.377  14.329   1.00 35.23  ? 194 MET A CB    1 
ATOM   1484  C  CG    . MET A 1 194 ? -34.799 -3.144  13.948   1.00 36.95  ? 194 MET A CG    1 
ATOM   1485  S  SD    . MET A 1 194 ? -34.122 -1.579  14.516   1.00 37.42  ? 194 MET A SD    1 
ATOM   1486  C  CE    . MET A 1 194 ? -34.039 -1.783  16.290   1.00 35.39  ? 194 MET A CE    1 
ATOM   1487  N  N     . GLY A 1 195 ? -31.451 -6.423  13.456   1.00 37.15  ? 195 GLY A N     1 
ATOM   1488  C  CA    . GLY A 1 195 ? -30.757 -7.639  13.839   1.00 36.94  ? 195 GLY A CA    1 
ATOM   1489  C  C     . GLY A 1 195 ? -29.330 -7.362  14.306   1.00 36.64  ? 195 GLY A C     1 
ATOM   1490  O  O     . GLY A 1 195 ? -28.721 -8.195  14.966   1.00 36.67  ? 195 GLY A O     1 
ATOM   1491  N  N     . ALA A 1 196 ? -28.815 -6.173  13.999   1.00 35.98  ? 196 ALA A N     1 
ATOM   1492  C  CA    . ALA A 1 196 ? -27.512 -5.756  14.506   1.00 36.09  ? 196 ALA A CA    1 
ATOM   1493  C  C     . ALA A 1 196 ? -27.593 -5.394  15.986   1.00 40.71  ? 196 ALA A C     1 
ATOM   1494  O  O     . ALA A 1 196 ? -26.566 -5.215  16.660   1.00 39.36  ? 196 ALA A O     1 
ATOM   1495  C  CB    . ALA A 1 196 ? -26.997 -4.591  13.714   1.00 32.72  ? 196 ALA A CB    1 
ATOM   1496  N  N     . MET A 1 197 ? -28.821 -5.268  16.500   1.00 38.83  ? 197 MET A N     1 
ATOM   1497  C  CA    . MET A 1 197 ? -28.971 -4.955  17.908   1.00 41.61  ? 197 MET A CA    1 
ATOM   1498  C  C     . MET A 1 197 ? -29.273 -6.249  18.654   1.00 43.14  ? 197 MET A C     1 
ATOM   1499  O  O     . MET A 1 197 ? -30.321 -6.843  18.428   1.00 39.86  ? 197 MET A O     1 
ATOM   1500  C  CB    . MET A 1 197 ? -30.102 -3.951  18.159   1.00 41.75  ? 197 MET A CB    1 
ATOM   1501  C  CG    . MET A 1 197 ? -30.377 -3.783  19.616   1.00 47.01  ? 197 MET A CG    1 
ATOM   1502  S  SD    . MET A 1 197 ? -31.829 -2.785  19.926   1.00 44.71  ? 197 MET A SD    1 
ATOM   1503  C  CE    . MET A 1 197 ? -31.677 -2.706  21.703   1.00 50.39  ? 197 MET A CE    1 
ATOM   1504  N  N     . PRO A 1 198 ? -28.398 -6.705  19.585   1.00 43.76  ? 198 PRO A N     1 
ATOM   1505  C  CA    . PRO A 1 198 ? -28.630 -7.959  20.307   1.00 42.39  ? 198 PRO A CA    1 
ATOM   1506  C  C     . PRO A 1 198 ? -29.869 -7.821  21.192   1.00 38.72  ? 198 PRO A C     1 
ATOM   1507  O  O     . PRO A 1 198 ? -30.111 -6.770  21.759   1.00 47.78  ? 198 PRO A O     1 
ATOM   1508  C  CB    . PRO A 1 198 ? -27.352 -8.145  21.143   1.00 45.15  ? 198 PRO A CB    1 
ATOM   1509  C  CG    . PRO A 1 198 ? -26.354 -7.161  20.576   1.00 47.34  ? 198 PRO A CG    1 
ATOM   1510  C  CD    . PRO A 1 198 ? -27.188 -6.015  20.052   1.00 44.17  ? 198 PRO A CD    1 
ATOM   1511  N  N     . GLY A 1 199 ? -30.686 -8.864  21.280   1.00 42.58  ? 199 GLY A N     1 
ATOM   1512  C  CA    . GLY A 1 199 ? -31.864 -8.837  22.137   1.00 42.49  ? 199 GLY A CA    1 
ATOM   1513  C  C     . GLY A 1 199 ? -33.105 -8.201  21.498   1.00 47.91  ? 199 GLY A C     1 
ATOM   1514  O  O     . GLY A 1 199 ? -34.118 -8.054  22.175   1.00 51.60  ? 199 GLY A O     1 
ATOM   1515  N  N     . ASN A 1 200 ? -33.051 -7.824  20.210   1.00 47.54  ? 200 ASN A N     1 
ATOM   1516  C  CA    . ASN A 1 200 ? -34.204 -7.227  19.535   1.00 47.48  ? 200 ASN A CA    1 
ATOM   1517  C  C     . ASN A 1 200 ? -35.224 -8.326  19.230   1.00 46.84  ? 200 ASN A C     1 
ATOM   1518  O  O     . ASN A 1 200 ? -34.863 -9.481  19.046   1.00 47.51  ? 200 ASN A O     1 
ATOM   1519  C  CB    . ASN A 1 200 ? -33.819 -6.540  18.216   1.00 45.34  ? 200 ASN A CB    1 
ATOM   1520  C  CG    . ASN A 1 200 ? -33.663 -7.552  17.096   1.00 48.76  ? 200 ASN A CG    1 
ATOM   1521  O  OD1   . ASN A 1 200 ? -34.637 -7.972  16.483   1.00 51.50  ? 200 ASN A OD1   1 
ATOM   1522  N  ND2   . ASN A 1 200 ? -32.450 -8.021  16.854   1.00 53.54  ? 200 ASN A ND2   1 
ATOM   1523  N  N     . ASN A 1 201 ? -36.498 -7.943  19.157   1.00 42.54  ? 201 ASN A N     1 
ATOM   1524  C  CA    . ASN A 1 201 ? -37.550 -8.757  18.603   1.00 39.77  ? 201 ASN A CA    1 
ATOM   1525  C  C     . ASN A 1 201 ? -38.121 -8.043  17.384   1.00 37.57  ? 201 ASN A C     1 
ATOM   1526  O  O     . ASN A 1 201 ? -39.300 -8.177  17.104   1.00 38.27  ? 201 ASN A O     1 
ATOM   1527  C  CB    . ASN A 1 201 ? -38.642 -9.017  19.647   1.00 46.17  ? 201 ASN A CB    1 
ATOM   1528  C  CG    . ASN A 1 201 ? -38.149 -9.885  20.789   1.00 54.29  ? 201 ASN A CG    1 
ATOM   1529  O  OD1   . ASN A 1 201 ? -38.008 -9.425  21.917   1.00 61.50  ? 201 ASN A OD1   1 
ATOM   1530  N  ND2   . ASN A 1 201 ? -37.825 -11.131 20.502   1.00 54.84  ? 201 ASN A ND2   1 
ATOM   1531  N  N     . THR A 1 202 ? -37.300 -7.247  16.696   1.00 35.45  ? 202 THR A N     1 
ATOM   1532  C  CA    . THR A 1 202 ? -37.803 -6.309  15.709   1.00 38.05  ? 202 THR A CA    1 
ATOM   1533  C  C     . THR A 1 202 ? -37.132 -6.498  14.345   1.00 39.47  ? 202 THR A C     1 
ATOM   1534  O  O     . THR A 1 202 ? -37.378 -5.723  13.419   1.00 36.22  ? 202 THR A O     1 
ATOM   1535  C  CB    . THR A 1 202 ? -37.642 -4.869  16.233   1.00 34.94  ? 202 THR A CB    1 
ATOM   1536  O  OG1   . THR A 1 202 ? -36.298 -4.681  16.669   1.00 32.14  ? 202 THR A OG1   1 
ATOM   1537  C  CG2   . THR A 1 202 ? -38.577 -4.562  17.375   1.00 32.87  ? 202 THR A CG2   1 
ATOM   1538  N  N     . TRP A 1 203 ? -36.317 -7.545  14.197   1.00 36.76  ? 203 TRP A N     1 
ATOM   1539  C  CA    . TRP A 1 203 ? -35.546 -7.775  12.984   1.00 35.72  ? 203 TRP A CA    1 
ATOM   1540  C  C     . TRP A 1 203 ? -36.438 -7.814  11.746   1.00 31.61  ? 203 TRP A C     1 
ATOM   1541  O  O     . TRP A 1 203 ? -36.064 -7.270  10.709   1.00 33.63  ? 203 TRP A O     1 
ATOM   1542  C  CB    . TRP A 1 203 ? -34.733 -9.069  13.107   1.00 35.94  ? 203 TRP A CB    1 
ATOM   1543  C  CG    . TRP A 1 203 ? -33.543 -9.169  12.200   1.00 36.76  ? 203 TRP A CG    1 
ATOM   1544  C  CD1   . TRP A 1 203 ? -32.969 -8.207  11.418   1.00 39.25  ? 203 TRP A CD1   1 
ATOM   1545  C  CD2   . TRP A 1 203 ? -32.776 -10.364 11.985   1.00 37.52  ? 203 TRP A CD2   1 
ATOM   1546  N  NE1   . TRP A 1 203 ? -31.862 -8.705  10.775   1.00 34.65  ? 203 TRP A NE1   1 
ATOM   1547  C  CE2   . TRP A 1 203 ? -31.728 -10.033 11.097   1.00 39.11  ? 203 TRP A CE2   1 
ATOM   1548  C  CE3   . TRP A 1 203 ? -32.855 -11.664 12.496   1.00 36.53  ? 203 TRP A CE3   1 
ATOM   1549  C  CZ2   . TRP A 1 203 ? -30.785 -10.980 10.695   1.00 38.66  ? 203 TRP A CZ2   1 
ATOM   1550  C  CZ3   . TRP A 1 203 ? -31.917 -12.594 12.101   1.00 38.92  ? 203 TRP A CZ3   1 
ATOM   1551  C  CH2   . TRP A 1 203 ? -30.904 -12.254 11.206   1.00 35.03  ? 203 TRP A CH2   1 
ATOM   1552  N  N     . GLN A 1 204 ? -37.636 -8.393  11.871   1.00 31.49  ? 204 GLN A N     1 
ATOM   1553  C  CA    . GLN A 1 204 ? -38.560 -8.498  10.750   1.00 33.41  ? 204 GLN A CA    1 
ATOM   1554  C  C     . GLN A 1 204 ? -39.683 -7.454  10.834   1.00 34.43  ? 204 GLN A C     1 
ATOM   1555  O  O     . GLN A 1 204 ? -40.715 -7.612  10.175   1.00 32.63  ? 204 GLN A O     1 
ATOM   1556  C  CB    . GLN A 1 204 ? -39.138 -9.919  10.682   1.00 36.77  ? 204 GLN A CB    1 
ATOM   1557  C  CG    . GLN A 1 204 ? -38.239 -10.900 9.944    1.00 37.25  ? 204 GLN A CG    1 
ATOM   1558  C  CD    . GLN A 1 204 ? -36.874 -11.050 10.579   1.00 38.85  ? 204 GLN A CD    1 
ATOM   1559  O  OE1   . GLN A 1 204 ? -36.733 -11.671 11.623   1.00 41.50  ? 204 GLN A OE1   1 
ATOM   1560  N  NE2   . GLN A 1 204 ? -35.843 -10.509 9.946    1.00 37.09  ? 204 GLN A NE2   1 
ATOM   1561  N  N     . LEU A 1 205 ? -39.506 -6.380  11.621   1.00 36.31  ? 205 LEU A N     1 
ATOM   1562  C  CA    . LEU A 1 205 ? -40.591 -5.416  11.807   1.00 33.44  ? 205 LEU A CA    1 
ATOM   1563  C  C     . LEU A 1 205 ? -40.221 -4.033  11.286   1.00 36.95  ? 205 LEU A C     1 
ATOM   1564  O  O     . LEU A 1 205 ? -41.096 -3.192  11.055   1.00 40.20  ? 205 LEU A O     1 
ATOM   1565  C  CB    . LEU A 1 205 ? -40.958 -5.330  13.289   1.00 37.77  ? 205 LEU A CB    1 
ATOM   1566  C  CG    . LEU A 1 205 ? -41.415 -6.628  13.942   1.00 39.93  ? 205 LEU A CG    1 
ATOM   1567  C  CD1   . LEU A 1 205 ? -41.863 -6.343  15.354   1.00 39.95  ? 205 LEU A CD1   1 
ATOM   1568  C  CD2   . LEU A 1 205 ? -42.523 -7.309  13.163   1.00 39.45  ? 205 LEU A CD2   1 
ATOM   1569  N  N     . PHE A 1 206 ? -38.925 -3.772  11.134   1.00 35.60  ? 206 PHE A N     1 
ATOM   1570  C  CA    . PHE A 1 206 ? -38.484 -2.438  10.776   1.00 38.06  ? 206 PHE A CA    1 
ATOM   1571  C  C     . PHE A 1 206 ? -37.216 -2.580  9.945    1.00 34.94  ? 206 PHE A C     1 
ATOM   1572  O  O     . PHE A 1 206 ? -36.220 -3.104  10.442   1.00 36.73  ? 206 PHE A O     1 
ATOM   1573  C  CB    . PHE A 1 206 ? -38.300 -1.606  12.056   1.00 38.91  ? 206 PHE A CB    1 
ATOM   1574  C  CG    . PHE A 1 206 ? -37.866 -0.173  11.845   1.00 40.55  ? 206 PHE A CG    1 
ATOM   1575  C  CD1   . PHE A 1 206 ? -38.769 0.789   11.427   1.00 41.35  ? 206 PHE A CD1   1 
ATOM   1576  C  CD2   . PHE A 1 206 ? -36.547 0.206   12.030   1.00 38.34  ? 206 PHE A CD2   1 
ATOM   1577  C  CE1   . PHE A 1 206 ? -38.364 2.100   11.221   1.00 43.28  ? 206 PHE A CE1   1 
ATOM   1578  C  CE2   . PHE A 1 206 ? -36.146 1.517   11.812   1.00 39.27  ? 206 PHE A CE2   1 
ATOM   1579  C  CZ    . PHE A 1 206 ? -37.054 2.464   11.424   1.00 39.81  ? 206 PHE A CZ    1 
ATOM   1580  N  N     . LYS A 1 207 ? -37.248 -2.050  8.718    1.00 31.95  ? 207 LYS A N     1 
ATOM   1581  C  CA    . LYS A 1 207 ? -36.217 -2.347  7.741    1.00 38.09  ? 207 LYS A CA    1 
ATOM   1582  C  C     . LYS A 1 207 ? -34.898 -1.689  8.100    1.00 36.96  ? 207 LYS A C     1 
ATOM   1583  O  O     . LYS A 1 207 ? -33.830 -2.288  7.940    1.00 39.62  ? 207 LYS A O     1 
ATOM   1584  C  CB    . LYS A 1 207 ? -36.575 -1.821  6.354    1.00 39.56  ? 207 LYS A CB    1 
ATOM   1585  C  CG    . LYS A 1 207 ? -37.585 -2.621  5.551    1.00 40.56  ? 207 LYS A CG    1 
ATOM   1586  C  CD    . LYS A 1 207 ? -37.964 -1.858  4.316    1.00 42.13  ? 207 LYS A CD    1 
ATOM   1587  C  CE    . LYS A 1 207 ? -38.681 -2.663  3.268    1.00 47.87  ? 207 LYS A CE    1 
ATOM   1588  N  NZ    . LYS A 1 207 ? -37.729 -3.535  2.549    1.00 47.40  ? 207 LYS A NZ    1 
ATOM   1589  N  N     . TYR A 1 208 ? -34.968 -0.417  8.502    1.00 39.53  ? 208 TYR A N     1 
ATOM   1590  C  CA    . TYR A 1 208 ? -33.771 0.400   8.439    1.00 34.58  ? 208 TYR A CA    1 
ATOM   1591  C  C     . TYR A 1 208 ? -32.739 0.036   9.493    1.00 34.21  ? 208 TYR A C     1 
ATOM   1592  O  O     . TYR A 1 208 ? -31.550 0.131   9.208    1.00 39.03  ? 208 TYR A O     1 
ATOM   1593  C  CB    . TYR A 1 208 ? -34.098 1.891   8.540    1.00 35.86  ? 208 TYR A CB    1 
ATOM   1594  C  CG    . TYR A 1 208 ? -35.004 2.404   7.459    1.00 39.64  ? 208 TYR A CG    1 
ATOM   1595  C  CD1   . TYR A 1 208 ? -34.759 2.150   6.122    1.00 41.20  ? 208 TYR A CD1   1 
ATOM   1596  C  CD2   . TYR A 1 208 ? -36.133 3.131   7.782    1.00 37.68  ? 208 TYR A CD2   1 
ATOM   1597  C  CE1   . TYR A 1 208 ? -35.612 2.616   5.135    1.00 45.17  ? 208 TYR A CE1   1 
ATOM   1598  C  CE2   . TYR A 1 208 ? -36.987 3.614   6.811    1.00 40.93  ? 208 TYR A CE2   1 
ATOM   1599  C  CZ    . TYR A 1 208 ? -36.719 3.371   5.481    1.00 44.13  ? 208 TYR A CZ    1 
ATOM   1600  O  OH    . TYR A 1 208 ? -37.583 3.891   4.555    1.00 41.93  ? 208 TYR A OH    1 
ATOM   1601  N  N     . GLY A 1 209 ? -33.179 -0.324  10.706   1.00 34.99  ? 209 GLY A N     1 
ATOM   1602  C  CA    . GLY A 1 209 ? -32.353 -0.088  11.874   1.00 38.71  ? 209 GLY A CA    1 
ATOM   1603  C  C     . GLY A 1 209 ? -31.887 1.376   11.932   1.00 39.79  ? 209 GLY A C     1 
ATOM   1604  O  O     . GLY A 1 209 ? -32.682 2.294   11.766   1.00 37.91  ? 209 GLY A O     1 
ATOM   1605  N  N     . TYR A 1 210 ? -30.584 1.591   12.146   1.00 38.42  ? 210 TYR A N     1 
ATOM   1606  C  CA    . TYR A 1 210 ? -30.028 2.934   12.218   1.00 39.71  ? 210 TYR A CA    1 
ATOM   1607  C  C     . TYR A 1 210 ? -28.790 3.008   11.336   1.00 40.63  ? 210 TYR A C     1 
ATOM   1608  O  O     . TYR A 1 210 ? -28.040 2.042   11.241   1.00 39.98  ? 210 TYR A O     1 
ATOM   1609  C  CB    . TYR A 1 210 ? -29.688 3.243   13.680   1.00 37.60  ? 210 TYR A CB    1 
ATOM   1610  C  CG    . TYR A 1 210 ? -28.824 4.444   13.960   1.00 38.71  ? 210 TYR A CG    1 
ATOM   1611  C  CD1   . TYR A 1 210 ? -29.327 5.730   13.854   1.00 41.78  ? 210 TYR A CD1   1 
ATOM   1612  C  CD2   . TYR A 1 210 ? -27.508 4.292   14.372   1.00 43.77  ? 210 TYR A CD2   1 
ATOM   1613  C  CE1   . TYR A 1 210 ? -28.542 6.837   14.122   1.00 38.75  ? 210 TYR A CE1   1 
ATOM   1614  C  CE2   . TYR A 1 210 ? -26.712 5.389   14.655   1.00 41.02  ? 210 TYR A CE2   1 
ATOM   1615  C  CZ    . TYR A 1 210 ? -27.237 6.661   14.531   1.00 41.73  ? 210 TYR A CZ    1 
ATOM   1616  O  OH    . TYR A 1 210 ? -26.474 7.746   14.838   1.00 46.73  ? 210 TYR A OH    1 
ATOM   1617  N  N     . GLY A 1 211 ? -28.566 4.175   10.727   1.00 38.17  ? 211 GLY A N     1 
ATOM   1618  C  CA    . GLY A 1 211 ? -27.376 4.398   9.930    1.00 39.45  ? 211 GLY A CA    1 
ATOM   1619  C  C     . GLY A 1 211 ? -27.651 4.077   8.462    1.00 37.82  ? 211 GLY A C     1 
ATOM   1620  O  O     . GLY A 1 211 ? -28.803 3.950   8.051    1.00 36.98  ? 211 GLY A O     1 
ATOM   1621  N  N     . PRO A 1 212 ? -26.601 3.898   7.651    1.00 32.83  ? 212 PRO A N     1 
ATOM   1622  C  CA    . PRO A 1 212 ? -26.768 3.600   6.230    1.00 34.85  ? 212 PRO A CA    1 
ATOM   1623  C  C     . PRO A 1 212 ? -27.613 2.348   6.001    1.00 33.32  ? 212 PRO A C     1 
ATOM   1624  O  O     . PRO A 1 212 ? -27.469 1.332   6.685    1.00 33.37  ? 212 PRO A O     1 
ATOM   1625  C  CB    . PRO A 1 212 ? -25.337 3.409   5.708    1.00 33.67  ? 212 PRO A CB    1 
ATOM   1626  C  CG    . PRO A 1 212 ? -24.442 4.004   6.750    1.00 34.45  ? 212 PRO A CG    1 
ATOM   1627  C  CD    . PRO A 1 212 ? -25.203 3.974   8.057    1.00 35.83  ? 212 PRO A CD    1 
ATOM   1628  N  N     . TYR A 1 213 ? -28.501 2.426   5.016    1.00 35.66  ? 213 TYR A N     1 
ATOM   1629  C  CA    . TYR A 1 213 ? -29.407 1.324   4.749    1.00 37.69  ? 213 TYR A CA    1 
ATOM   1630  C  C     . TYR A 1 213 ? -28.759 0.467   3.674    1.00 34.60  ? 213 TYR A C     1 
ATOM   1631  O  O     . TYR A 1 213 ? -28.643 0.925   2.553    1.00 38.92  ? 213 TYR A O     1 
ATOM   1632  C  CB    . TYR A 1 213 ? -30.779 1.884   4.371    1.00 38.82  ? 213 TYR A CB    1 
ATOM   1633  C  CG    . TYR A 1 213 ? -31.772 0.821   3.989    1.00 43.25  ? 213 TYR A CG    1 
ATOM   1634  C  CD1   . TYR A 1 213 ? -31.844 -0.354  4.710    1.00 45.06  ? 213 TYR A CD1   1 
ATOM   1635  C  CD2   . TYR A 1 213 ? -32.664 1.002   2.939    1.00 46.27  ? 213 TYR A CD2   1 
ATOM   1636  C  CE1   . TYR A 1 213 ? -32.732 -1.357  4.372    1.00 48.87  ? 213 TYR A CE1   1 
ATOM   1637  C  CE2   . TYR A 1 213 ? -33.571 0.017   2.598    1.00 51.51  ? 213 TYR A CE2   1 
ATOM   1638  C  CZ    . TYR A 1 213 ? -33.584 -1.178  3.304    1.00 49.74  ? 213 TYR A CZ    1 
ATOM   1639  O  OH    . TYR A 1 213 ? -34.436 -2.202  3.030    1.00 57.54  ? 213 TYR A OH    1 
ATOM   1640  N  N     . VAL A 1 214 ? -28.251 -0.716  4.051    1.00 34.74  ? 214 VAL A N     1 
ATOM   1641  C  CA    . VAL A 1 214 ? -27.304 -1.466  3.243    1.00 34.94  ? 214 VAL A CA    1 
ATOM   1642  C  C     . VAL A 1 214 ? -27.884 -2.781  2.699    1.00 35.98  ? 214 VAL A C     1 
ATOM   1643  O  O     . VAL A 1 214 ? -27.226 -3.453  1.890    1.00 41.07  ? 214 VAL A O     1 
ATOM   1644  C  CB    . VAL A 1 214 ? -26.011 -1.769  4.024    1.00 37.05  ? 214 VAL A CB    1 
ATOM   1645  C  CG1   . VAL A 1 214 ? -25.154 -0.533  4.238    1.00 34.98  ? 214 VAL A CG1   1 
ATOM   1646  C  CG2   . VAL A 1 214 ? -26.298 -2.512  5.324    1.00 39.96  ? 214 VAL A CG2   1 
ATOM   1647  N  N     . ASP A 1 215 ? -29.095 -3.161  3.099    1.00 33.77  ? 215 ASP A N     1 
ATOM   1648  C  CA    . ASP A 1 215 ? -29.651 -4.444  2.678    1.00 38.04  ? 215 ASP A CA    1 
ATOM   1649  C  C     . ASP A 1 215 ? -29.606 -4.596  1.159    1.00 41.42  ? 215 ASP A C     1 
ATOM   1650  O  O     . ASP A 1 215 ? -29.286 -5.676  0.631    1.00 35.90  ? 215 ASP A O     1 
ATOM   1651  C  CB    . ASP A 1 215 ? -31.083 -4.635  3.181    1.00 40.36  ? 215 ASP A CB    1 
ATOM   1652  C  CG    . ASP A 1 215 ? -31.179 -4.834  4.689    1.00 41.85  ? 215 ASP A CG    1 
ATOM   1653  O  OD1   . ASP A 1 215 ? -30.857 -3.875  5.411    1.00 40.08  ? 215 ASP A OD1   1 
ATOM   1654  O  OD2   . ASP A 1 215 ? -31.520 -5.980  5.130    1.00 41.41  ? 215 ASP A OD2   1 
ATOM   1655  N  N     . GLY A 1 216 ? -29.967 -3.507  0.470    1.00 35.60  ? 216 GLY A N     1 
ATOM   1656  C  CA    . GLY A 1 216 ? -30.017 -3.448  -0.980   1.00 33.42  ? 216 GLY A CA    1 
ATOM   1657  C  C     . GLY A 1 216 ? -28.686 -3.757  -1.660   1.00 32.58  ? 216 GLY A C     1 
ATOM   1658  O  O     . GLY A 1 216 ? -28.688 -4.271  -2.763   1.00 32.47  ? 216 GLY A O     1 
ATOM   1659  N  N     . ILE A 1 217 ? -27.554 -3.490  -1.003   1.00 36.41  ? 217 ILE A N     1 
ATOM   1660  C  CA    . ILE A 1 217 ? -26.281 -3.733  -1.653   1.00 33.23  ? 217 ILE A CA    1 
ATOM   1661  C  C     . ILE A 1 217 ? -26.011 -5.237  -1.783   1.00 36.93  ? 217 ILE A C     1 
ATOM   1662  O  O     . ILE A 1 217 ? -25.113 -5.609  -2.528   1.00 37.37  ? 217 ILE A O     1 
ATOM   1663  C  CB    . ILE A 1 217 ? -25.137 -2.997  -0.945   1.00 38.92  ? 217 ILE A CB    1 
ATOM   1664  C  CG1   . ILE A 1 217 ? -24.576 -3.782  0.245    1.00 37.53  ? 217 ILE A CG1   1 
ATOM   1665  C  CG2   . ILE A 1 217 ? -25.546 -1.570  -0.578   1.00 39.49  ? 217 ILE A CG2   1 
ATOM   1666  C  CD1   . ILE A 1 217 ? -23.291 -3.215  0.732    1.00 41.74  ? 217 ILE A CD1   1 
ATOM   1667  N  N     . PHE A 1 218 ? -26.809 -6.101  -1.126   1.00 38.89  ? 218 PHE A N     1 
ATOM   1668  C  CA    . PHE A 1 218 ? -26.624 -7.542  -1.233   1.00 38.11  ? 218 PHE A CA    1 
ATOM   1669  C  C     . PHE A 1 218 ? -27.678 -8.170  -2.146   1.00 39.14  ? 218 PHE A C     1 
ATOM   1670  O  O     . PHE A 1 218 ? -27.814 -9.393  -2.202   1.00 41.48  ? 218 PHE A O     1 
ATOM   1671  C  CB    . PHE A 1 218 ? -26.659 -8.182  0.159    1.00 37.75  ? 218 PHE A CB    1 
ATOM   1672  C  CG    . PHE A 1 218 ? -25.637 -7.605  1.102    1.00 40.21  ? 218 PHE A CG    1 
ATOM   1673  C  CD1   . PHE A 1 218 ? -24.296 -7.884  0.940    1.00 36.15  ? 218 PHE A CD1   1 
ATOM   1674  C  CD2   . PHE A 1 218 ? -26.013 -6.765  2.139    1.00 40.23  ? 218 PHE A CD2   1 
ATOM   1675  C  CE1   . PHE A 1 218 ? -23.342 -7.344  1.789    1.00 38.88  ? 218 PHE A CE1   1 
ATOM   1676  C  CE2   . PHE A 1 218 ? -25.058 -6.221  2.984    1.00 41.26  ? 218 PHE A CE2   1 
ATOM   1677  C  CZ    . PHE A 1 218 ? -23.724 -6.512  2.816    1.00 37.08  ? 218 PHE A CZ    1 
ATOM   1678  N  N     . SER A 1 219 ? -28.453 -7.336  -2.841   1.00 36.32  ? 219 SER A N     1 
ATOM   1679  C  CA    . SER A 1 219 ? -29.366 -7.804  -3.871   1.00 35.89  ? 219 SER A CA    1 
ATOM   1680  C  C     . SER A 1 219 ? -28.729 -7.529  -5.231   1.00 37.26  ? 219 SER A C     1 
ATOM   1681  O  O     . SER A 1 219 ? -28.055 -6.509  -5.398   1.00 35.07  ? 219 SER A O     1 
ATOM   1682  C  CB    . SER A 1 219 ? -30.714 -7.133  -3.736   1.00 35.40  ? 219 SER A CB    1 
ATOM   1683  O  OG    . SER A 1 219 ? -30.592 -5.729  -3.983   1.00 37.42  ? 219 SER A OG    1 
ATOM   1684  N  N     . GLN A 1 220 ? -28.932 -8.446  -6.190   1.00 37.94  ? 220 GLN A N     1 
ATOM   1685  C  CA    . GLN A 1 220 ? -28.243 -8.445  -7.481   1.00 36.65  ? 220 GLN A CA    1 
ATOM   1686  C  C     . GLN A 1 220 ? -26.759 -8.093  -7.335   1.00 39.33  ? 220 GLN A C     1 
ATOM   1687  O  O     . GLN A 1 220 ? -26.238 -7.216  -8.034   1.00 39.79  ? 220 GLN A O     1 
ATOM   1688  C  CB    . GLN A 1 220 ? -28.942 -7.528  -8.487   1.00 39.51  ? 220 GLN A CB    1 
ATOM   1689  C  CG    . GLN A 1 220 ? -30.342 -8.016  -8.872   1.00 38.21  ? 220 GLN A CG    1 
ATOM   1690  C  CD    . GLN A 1 220 ? -30.889 -7.369  -10.126  1.00 38.10  ? 220 GLN A CD    1 
ATOM   1691  O  OE1   . GLN A 1 220 ? -30.378 -6.367  -10.623  1.00 38.19  ? 220 GLN A OE1   1 
ATOM   1692  N  NE2   . GLN A 1 220 ? -31.983 -7.919  -10.634  1.00 43.19  ? 220 GLN A NE2   1 
ATOM   1693  N  N     . SER A 1 221 ? -26.061 -8.867  -6.501   1.00 38.46  ? 221 SER A N     1 
ATOM   1694  C  CA    . SER A 1 221 ? -24.761 -8.458  -6.011   1.00 40.13  ? 221 SER A CA    1 
ATOM   1695  C  C     . SER A 1 221 ? -23.857 -9.652  -5.727   1.00 35.80  ? 221 SER A C     1 
ATOM   1696  O  O     . SER A 1 221 ? -24.342 -10.762 -5.540   1.00 35.41  ? 221 SER A O     1 
ATOM   1697  C  CB    . SER A 1 221 ? -24.975 -7.613  -4.781   1.00 40.82  ? 221 SER A CB    1 
ATOM   1698  O  OG    . SER A 1 221 ? -23.769 -7.284  -4.144   1.00 45.25  ? 221 SER A OG    1 
ATOM   1699  N  N     . ASN A 1 222 ? -22.545 -9.374  -5.698   1.00 36.30  ? 222 ASN A N     1 
ATOM   1700  C  CA    . ASN A 1 222 ? -21.533 -10.305 -5.229   1.00 39.08  ? 222 ASN A CA    1 
ATOM   1701  C  C     . ASN A 1 222 ? -20.771 -9.680  -4.058   1.00 40.39  ? 222 ASN A C     1 
ATOM   1702  O  O     . ASN A 1 222 ? -19.578 -9.943  -3.890   1.00 36.39  ? 222 ASN A O     1 
ATOM   1703  C  CB    . ASN A 1 222 ? -20.580 -10.717 -6.360   1.00 40.60  ? 222 ASN A CB    1 
ATOM   1704  C  CG    . ASN A 1 222 ? -20.032 -9.551  -7.175   1.00 38.47  ? 222 ASN A CG    1 
ATOM   1705  O  OD1   . ASN A 1 222 ? -20.104 -8.397  -6.771   1.00 38.60  ? 222 ASN A OD1   1 
ATOM   1706  N  ND2   . ASN A 1 222 ? -19.419 -9.844  -8.311   1.00 36.41  ? 222 ASN A ND2   1 
ATOM   1707  N  N     . PHE A 1 223 ? -21.483 -8.896  -3.230   1.00 36.19  ? 223 PHE A N     1 
ATOM   1708  C  CA    . PHE A 1 223 ? -20.903 -8.214  -2.077   1.00 37.04  ? 223 PHE A CA    1 
ATOM   1709  C  C     . PHE A 1 223 ? -21.039 -9.036  -0.795   1.00 39.33  ? 223 PHE A C     1 
ATOM   1710  O  O     . PHE A 1 223 ? -20.445 -8.695  0.234    1.00 41.21  ? 223 PHE A O     1 
ATOM   1711  C  CB    . PHE A 1 223 ? -21.544 -6.846  -1.845   1.00 38.32  ? 223 PHE A CB    1 
ATOM   1712  C  CG    . PHE A 1 223 ? -21.268 -5.816  -2.903   1.00 37.99  ? 223 PHE A CG    1 
ATOM   1713  C  CD1   . PHE A 1 223 ? -20.339 -6.035  -3.900   1.00 44.55  ? 223 PHE A CD1   1 
ATOM   1714  C  CD2   . PHE A 1 223 ? -21.965 -4.622  -2.906   1.00 43.20  ? 223 PHE A CD2   1 
ATOM   1715  C  CE1   . PHE A 1 223 ? -20.100 -5.063  -4.865   1.00 45.88  ? 223 PHE A CE1   1 
ATOM   1716  C  CE2   . PHE A 1 223 ? -21.725 -3.655  -3.874   1.00 42.67  ? 223 PHE A CE2   1 
ATOM   1717  C  CZ    . PHE A 1 223 ? -20.804 -3.886  -4.862   1.00 38.90  ? 223 PHE A CZ    1 
ATOM   1718  N  N     . GLY A 1 224 ? -21.776 -10.138 -0.859   1.00 36.96  ? 224 GLY A N     1 
ATOM   1719  C  CA    . GLY A 1 224 ? -21.856 -11.040 0.270    1.00 37.50  ? 224 GLY A CA    1 
ATOM   1720  C  C     . GLY A 1 224 ? -22.721 -12.257 -0.021   1.00 37.75  ? 224 GLY A C     1 
ATOM   1721  O  O     . GLY A 1 224 ? -23.410 -12.307 -1.017   1.00 40.07  ? 224 GLY A O     1 
ATOM   1722  N  N     . VAL A 1 225 ? -22.716 -13.220 0.904    1.00 44.32  ? 225 VAL A N     1 
ATOM   1723  C  CA    . VAL A 1 225 ? -23.618 -14.350 0.829    1.00 38.32  ? 225 VAL A CA    1 
ATOM   1724  C  C     . VAL A 1 225 ? -24.677 -14.173 1.904    1.00 36.17  ? 225 VAL A C     1 
ATOM   1725  O  O     . VAL A 1 225 ? -24.344 -14.171 3.082    1.00 38.33  ? 225 VAL A O     1 
ATOM   1726  C  CB    . VAL A 1 225 ? -22.858 -15.672 1.040    1.00 40.04  ? 225 VAL A CB    1 
ATOM   1727  C  CG1   . VAL A 1 225 ? -23.767 -16.879 0.885    1.00 39.10  ? 225 VAL A CG1   1 
ATOM   1728  C  CG2   . VAL A 1 225 ? -21.668 -15.776 0.104    1.00 41.83  ? 225 VAL A CG2   1 
ATOM   1729  N  N     . VAL A 1 226 ? -25.950 -14.141 1.497    1.00 38.53  ? 226 VAL A N     1 
ATOM   1730  C  CA    . VAL A 1 226 ? -27.055 -14.027 2.427    1.00 37.84  ? 226 VAL A CA    1 
ATOM   1731  C  C     . VAL A 1 226 ? -27.419 -15.399 3.003    1.00 40.52  ? 226 VAL A C     1 
ATOM   1732  O  O     . VAL A 1 226 ? -27.712 -16.324 2.248    1.00 40.16  ? 226 VAL A O     1 
ATOM   1733  C  CB    . VAL A 1 226 ? -28.250 -13.371 1.726    1.00 38.53  ? 226 VAL A CB    1 
ATOM   1734  C  CG1   . VAL A 1 226 ? -29.454 -13.317 2.654    1.00 42.08  ? 226 VAL A CG1   1 
ATOM   1735  C  CG2   . VAL A 1 226 ? -27.901 -11.981 1.223    1.00 40.89  ? 226 VAL A CG2   1 
ATOM   1736  N  N     . THR A 1 227 ? -27.485 -15.507 4.346    1.00 37.52  ? 227 THR A N     1 
ATOM   1737  C  CA    . THR A 1 227 ? -27.654 -16.805 4.992    1.00 38.56  ? 227 THR A CA    1 
ATOM   1738  C  C     . THR A 1 227 ? -28.976 -16.896 5.751    1.00 39.95  ? 227 THR A C     1 
ATOM   1739  O  O     . THR A 1 227 ? -29.439 -18.004 6.052    1.00 36.82  ? 227 THR A O     1 
ATOM   1740  C  CB    . THR A 1 227 ? -26.478 -17.139 5.918    1.00 39.00  ? 227 THR A CB    1 
ATOM   1741  O  OG1   . THR A 1 227 ? -26.341 -16.069 6.852    1.00 40.67  ? 227 THR A OG1   1 
ATOM   1742  C  CG2   . THR A 1 227 ? -25.169 -17.374 5.181    1.00 38.51  ? 227 THR A CG2   1 
ATOM   1743  N  N     . LYS A 1 228 ? -29.560 -15.727 6.053    1.00 36.76  ? 228 LYS A N     1 
ATOM   1744  C  CA    . LYS A 1 228 ? -30.891 -15.627 6.618    1.00 34.64  ? 228 LYS A CA    1 
ATOM   1745  C  C     . LYS A 1 228 ? -31.521 -14.340 6.083    1.00 36.56  ? 228 LYS A C     1 
ATOM   1746  O  O     . LYS A 1 228 ? -30.819 -13.348 5.859    1.00 37.58  ? 228 LYS A O     1 
ATOM   1747  C  CB    . LYS A 1 228 ? -30.837 -15.577 8.153    1.00 34.72  ? 228 LYS A CB    1 
ATOM   1748  C  CG    . LYS A 1 228 ? -30.287 -16.805 8.885    1.00 38.67  ? 228 LYS A CG    1 
ATOM   1749  C  CD    . LYS A 1 228 ? -30.112 -16.539 10.377   1.00 38.03  ? 228 LYS A CD    1 
ATOM   1750  C  CE    . LYS A 1 228 ? -29.525 -17.672 11.192   1.00 38.21  ? 228 LYS A CE    1 
ATOM   1751  N  NZ    . LYS A 1 228 ? -28.224 -18.102 10.630   1.00 42.81  ? 228 LYS A NZ    1 
ATOM   1752  N  N     . MET A 1 229 ? -32.848 -14.344 5.909    1.00 37.38  ? 229 MET A N     1 
ATOM   1753  C  CA    . MET A 1 229 ? -33.526 -13.172 5.377    1.00 36.88  ? 229 MET A CA    1 
ATOM   1754  C  C     . MET A 1 229 ? -34.952 -13.166 5.882    1.00 35.05  ? 229 MET A C     1 
ATOM   1755  O  O     . MET A 1 229 ? -35.591 -14.214 5.951    1.00 33.56  ? 229 MET A O     1 
ATOM   1756  C  CB    . MET A 1 229 ? -33.547 -13.194 3.849    1.00 37.61  ? 229 MET A CB    1 
ATOM   1757  C  CG    . MET A 1 229 ? -33.887 -11.845 3.219    1.00 38.24  ? 229 MET A CG    1 
ATOM   1758  S  SD    . MET A 1 229 ? -34.274 -12.022 1.445    1.00 39.54  ? 229 MET A SD    1 
ATOM   1759  C  CE    . MET A 1 229 ? -35.984 -12.550 1.540    1.00 35.79  ? 229 MET A CE    1 
ATOM   1760  N  N     . GLY A 1 230 ? -35.438 -11.975 6.256    1.00 36.14  ? 230 GLY A N     1 
ATOM   1761  C  CA    . GLY A 1 230 ? -36.831 -11.832 6.637    1.00 32.76  ? 230 GLY A CA    1 
ATOM   1762  C  C     . GLY A 1 230 ? -37.654 -11.376 5.454    1.00 32.04  ? 230 GLY A C     1 
ATOM   1763  O  O     . GLY A 1 230 ? -37.141 -10.710 4.550    1.00 35.28  ? 230 GLY A O     1 
ATOM   1764  N  N     . ILE A 1 231 ? -38.934 -11.716 5.472    1.00 33.81  ? 231 ILE A N     1 
ATOM   1765  C  CA    . ILE A 1 231 ? -39.814 -11.235 4.440    1.00 34.09  ? 231 ILE A CA    1 
ATOM   1766  C  C     . ILE A 1 231 ? -41.194 -11.040 5.037    1.00 35.84  ? 231 ILE A C     1 
ATOM   1767  O  O     . ILE A 1 231 ? -41.633 -11.809 5.887    1.00 39.62  ? 231 ILE A O     1 
ATOM   1768  C  CB    . ILE A 1 231 ? -39.824 -12.173 3.220    1.00 38.79  ? 231 ILE A CB    1 
ATOM   1769  C  CG1   . ILE A 1 231 ? -40.510 -11.494 2.039    1.00 41.58  ? 231 ILE A CG1   1 
ATOM   1770  C  CG2   . ILE A 1 231 ? -40.461 -13.519 3.557    1.00 41.08  ? 231 ILE A CG2   1 
ATOM   1771  C  CD1   . ILE A 1 231 ? -40.191 -12.099 0.685    1.00 46.95  ? 231 ILE A CD1   1 
ATOM   1772  N  N     . TRP A 1 232 ? -41.871 -9.987  4.580    1.00 34.94  ? 232 TRP A N     1 
ATOM   1773  C  CA    . TRP A 1 232 ? -43.180 -9.684  5.085    1.00 34.11  ? 232 TRP A CA    1 
ATOM   1774  C  C     . TRP A 1 232 ? -44.170 -10.534 4.324    1.00 33.69  ? 232 TRP A C     1 
ATOM   1775  O  O     . TRP A 1 232 ? -44.014 -10.712 3.115    1.00 31.86  ? 232 TRP A O     1 
ATOM   1776  C  CB    . TRP A 1 232 ? -43.490 -8.190  4.951    1.00 37.64  ? 232 TRP A CB    1 
ATOM   1777  C  CG    . TRP A 1 232 ? -42.671 -7.317  5.856    1.00 39.42  ? 232 TRP A CG    1 
ATOM   1778  C  CD1   . TRP A 1 232 ? -42.057 -7.665  7.022    1.00 38.38  ? 232 TRP A CD1   1 
ATOM   1779  C  CD2   . TRP A 1 232 ? -42.330 -5.942  5.627    1.00 33.55  ? 232 TRP A CD2   1 
ATOM   1780  N  NE1   . TRP A 1 232 ? -41.379 -6.600  7.542    1.00 37.63  ? 232 TRP A NE1   1 
ATOM   1781  C  CE2   . TRP A 1 232 ? -41.517 -5.534  6.698    1.00 34.53  ? 232 TRP A CE2   1 
ATOM   1782  C  CE3   . TRP A 1 232 ? -42.650 -5.020  4.628    1.00 33.93  ? 232 TRP A CE3   1 
ATOM   1783  C  CZ2   . TRP A 1 232 ? -41.054 -4.226  6.830    1.00 35.71  ? 232 TRP A CZ2   1 
ATOM   1784  C  CZ3   . TRP A 1 232 ? -42.166 -3.732  4.741    1.00 39.93  ? 232 TRP A CZ3   1 
ATOM   1785  C  CH2   . TRP A 1 232 ? -41.364 -3.350  5.824    1.00 35.69  ? 232 TRP A CH2   1 
ATOM   1786  N  N     . LEU A 1 233 ? -45.220 -10.957 5.042    1.00 34.45  ? 233 LEU A N     1 
ATOM   1787  C  CA    . LEU A 1 233 ? -46.281 -11.805 4.511    1.00 36.05  ? 233 LEU A CA    1 
ATOM   1788  C  C     . LEU A 1 233 ? -47.637 -11.142 4.679    1.00 35.20  ? 233 LEU A C     1 
ATOM   1789  O  O     . LEU A 1 233 ? -47.954 -10.700 5.770    1.00 37.75  ? 233 LEU A O     1 
ATOM   1790  C  CB    . LEU A 1 233 ? -46.263 -13.106 5.315    1.00 36.27  ? 233 LEU A CB    1 
ATOM   1791  C  CG    . LEU A 1 233 ? -45.009 -13.947 5.157    1.00 35.47  ? 233 LEU A CG    1 
ATOM   1792  C  CD1   . LEU A 1 233 ? -45.227 -15.296 5.823    1.00 37.12  ? 233 LEU A CD1   1 
ATOM   1793  C  CD2   . LEU A 1 233 ? -44.662 -14.111 3.673    1.00 40.18  ? 233 LEU A CD2   1 
ATOM   1794  N  N     . MET A 1 234 ? -48.447 -11.157 3.625    1.00 35.52  ? 234 MET A N     1 
ATOM   1795  C  CA    . MET A 1 234 ? -49.731 -10.496 3.661    1.00 40.39  ? 234 MET A CA    1 
ATOM   1796  C  C     . MET A 1 234 ? -50.695 -11.303 4.518    1.00 41.68  ? 234 MET A C     1 
ATOM   1797  O  O     . MET A 1 234 ? -50.798 -12.519 4.348    1.00 40.21  ? 234 MET A O     1 
ATOM   1798  C  CB    . MET A 1 234 ? -50.305 -10.374 2.254    1.00 43.99  ? 234 MET A CB    1 
ATOM   1799  C  CG    . MET A 1 234 ? -51.556 -9.520  2.182    1.00 45.25  ? 234 MET A CG    1 
ATOM   1800  S  SD    . MET A 1 234 ? -52.066 -9.266  0.462    1.00 46.49  ? 234 MET A SD    1 
ATOM   1801  C  CE    . MET A 1 234 ? -52.625 -10.915 0.067    1.00 51.95  ? 234 MET A CE    1 
ATOM   1802  N  N     . PRO A 1 235 ? -51.415 -10.658 5.464    1.00 43.72  ? 235 PRO A N     1 
ATOM   1803  C  CA    . PRO A 1 235 ? -52.526 -11.301 6.164    1.00 42.73  ? 235 PRO A CA    1 
ATOM   1804  C  C     . PRO A 1 235 ? -53.560 -11.773 5.157    1.00 41.25  ? 235 PRO A C     1 
ATOM   1805  O  O     . PRO A 1 235 ? -53.871 -11.080 4.200    1.00 37.72  ? 235 PRO A O     1 
ATOM   1806  C  CB    . PRO A 1 235 ? -53.105 -10.196 7.071    1.00 41.47  ? 235 PRO A CB    1 
ATOM   1807  C  CG    . PRO A 1 235 ? -51.915 -9.284  7.301    1.00 44.07  ? 235 PRO A CG    1 
ATOM   1808  C  CD    . PRO A 1 235 ? -51.153 -9.307  5.988    1.00 44.04  ? 235 PRO A CD    1 
ATOM   1809  N  N     . GLU A 1 236 ? -54.104 -12.963 5.371    1.00 43.08  ? 236 GLU A N     1 
ATOM   1810  C  CA    . GLU A 1 236 ? -55.241 -13.391 4.569    1.00 45.96  ? 236 GLU A CA    1 
ATOM   1811  C  C     . GLU A 1 236 ? -56.257 -12.250 4.477    1.00 38.41  ? 236 GLU A C     1 
ATOM   1812  O  O     . GLU A 1 236 ? -56.700 -11.728 5.488    1.00 44.85  ? 236 GLU A O     1 
ATOM   1813  C  CB    . GLU A 1 236 ? -55.855 -14.641 5.198    1.00 47.76  ? 236 GLU A CB    1 
ATOM   1814  C  CG    . GLU A 1 236 ? -56.909 -15.319 4.349    1.00 52.49  ? 236 GLU A CG    1 
ATOM   1815  C  CD    . GLU A 1 236 ? -57.457 -16.558 5.041    1.00 57.51  ? 236 GLU A CD    1 
ATOM   1816  O  OE1   . GLU A 1 236 ? -58.673 -16.658 5.187    1.00 73.30  ? 236 GLU A OE1   1 
ATOM   1817  O  OE2   . GLU A 1 236 ? -56.654 -17.383 5.496    1.00 57.03  ? 236 GLU A OE2   1 
ATOM   1818  N  N     . PRO A 1 237 ? -56.639 -11.775 3.280    1.00 40.90  ? 237 PRO A N     1 
ATOM   1819  C  CA    . PRO A 1 237 ? -57.636 -10.707 3.180    1.00 43.06  ? 237 PRO A CA    1 
ATOM   1820  C  C     . PRO A 1 237 ? -59.059 -11.215 3.413    1.00 42.35  ? 237 PRO A C     1 
ATOM   1821  O  O     . PRO A 1 237 ? -59.304 -12.413 3.395    1.00 40.03  ? 237 PRO A O     1 
ATOM   1822  C  CB    . PRO A 1 237 ? -57.433 -10.193 1.758    1.00 44.18  ? 237 PRO A CB    1 
ATOM   1823  C  CG    . PRO A 1 237 ? -56.952 -11.407 1.014    1.00 44.71  ? 237 PRO A CG    1 
ATOM   1824  C  CD    . PRO A 1 237 ? -56.059 -12.135 1.988    1.00 43.87  ? 237 PRO A CD    1 
ATOM   1825  N  N     . ALA A 1 238 ? -59.985 -10.282 3.629    1.00 43.27  ? 238 ALA A N     1 
ATOM   1826  C  CA    . ALA A 1 238 ? -61.387 -10.591 3.861    1.00 43.22  ? 238 ALA A CA    1 
ATOM   1827  C  C     . ALA A 1 238 ? -62.117 -11.033 2.590    1.00 45.57  ? 238 ALA A C     1 
ATOM   1828  O  O     . ALA A 1 238 ? -63.280 -11.407 2.650    1.00 49.13  ? 238 ALA A O     1 
ATOM   1829  C  CB    . ALA A 1 238 ? -62.053 -9.366  4.439    1.00 42.62  ? 238 ALA A CB    1 
ATOM   1830  N  N     . GLY A 1 239 ? -61.478 -10.944 1.419    1.00 45.86  ? 239 GLY A N     1 
ATOM   1831  C  CA    . GLY A 1 239 ? -62.114 -11.327 0.165    1.00 40.22  ? 239 GLY A CA    1 
ATOM   1832  C  C     . GLY A 1 239 ? -61.127 -11.247 -0.998   1.00 45.93  ? 239 GLY A C     1 
ATOM   1833  O  O     . GLY A 1 239 ? -60.104 -10.561 -0.904   1.00 37.87  ? 239 GLY A O     1 
ATOM   1834  N  N     . TYR A 1 240 ? -61.473 -11.935 -2.090   1.00 43.55  ? 240 TYR A N     1 
ATOM   1835  C  CA    . TYR A 1 240 ? -60.573 -12.143 -3.204   1.00 42.84  ? 240 TYR A CA    1 
ATOM   1836  C  C     . TYR A 1 240 ? -61.389 -12.419 -4.454   1.00 42.86  ? 240 TYR A C     1 
ATOM   1837  O  O     . TYR A 1 240 ? -62.111 -13.405 -4.515   1.00 42.52  ? 240 TYR A O     1 
ATOM   1838  C  CB    . TYR A 1 240 ? -59.641 -13.325 -2.926   1.00 41.79  ? 240 TYR A CB    1 
ATOM   1839  C  CG    . TYR A 1 240 ? -58.712 -13.643 -4.067   1.00 41.37  ? 240 TYR A CG    1 
ATOM   1840  C  CD1   . TYR A 1 240 ? -57.793 -12.712 -4.532   1.00 42.50  ? 240 TYR A CD1   1 
ATOM   1841  C  CD2   . TYR A 1 240 ? -58.775 -14.858 -4.716   1.00 38.68  ? 240 TYR A CD2   1 
ATOM   1842  C  CE1   . TYR A 1 240 ? -56.951 -12.989 -5.597   1.00 40.07  ? 240 TYR A CE1   1 
ATOM   1843  C  CE2   . TYR A 1 240 ? -57.926 -15.163 -5.769   1.00 40.10  ? 240 TYR A CE2   1 
ATOM   1844  C  CZ    . TYR A 1 240 ? -57.003 -14.232 -6.210   1.00 41.67  ? 240 TYR A CZ    1 
ATOM   1845  O  OH    . TYR A 1 240 ? -56.175 -14.543 -7.272   1.00 37.74  ? 240 TYR A OH    1 
ATOM   1846  N  N     . ARG A 1 241 ? -61.296 -11.520 -5.434   1.00 41.20  ? 241 ARG A N     1 
ATOM   1847  C  CA    . ARG A 1 241 ? -61.957 -11.712 -6.711   1.00 44.05  ? 241 ARG A CA    1 
ATOM   1848  C  C     . ARG A 1 241 ? -60.950 -11.483 -7.829   1.00 40.18  ? 241 ARG A C     1 
ATOM   1849  O  O     . ARG A 1 241 ? -60.600 -10.341 -8.093   1.00 40.67  ? 241 ARG A O     1 
ATOM   1850  C  CB    . ARG A 1 241 ? -63.152 -10.763 -6.844   1.00 43.66  ? 241 ARG A CB    1 
ATOM   1851  C  CG    . ARG A 1 241 ? -64.278 -11.070 -5.872   1.00 48.02  ? 241 ARG A CG    1 
ATOM   1852  C  CD    . ARG A 1 241 ? -65.139 -12.222 -6.391   1.00 50.47  ? 241 ARG A CD    1 
ATOM   1853  N  NE    . ARG A 1 241 ? -66.061 -11.792 -7.444   1.00 52.57  ? 241 ARG A NE    1 
ATOM   1854  C  CZ    . ARG A 1 241 ? -66.550 -12.584 -8.397   1.00 51.34  ? 241 ARG A CZ    1 
ATOM   1855  N  NH1   . ARG A 1 241 ? -66.129 -13.838 -8.513   1.00 49.11  ? 241 ARG A NH1   1 
ATOM   1856  N  NH2   . ARG A 1 241 ? -67.433 -12.103 -9.257   1.00 48.19  ? 241 ARG A NH2   1 
ATOM   1857  N  N     . PRO A 1 242 ? -60.480 -12.545 -8.523   1.00 41.60  ? 242 PRO A N     1 
ATOM   1858  C  CA    . PRO A 1 242 ? -59.598 -12.386 -9.680   1.00 39.81  ? 242 PRO A CA    1 
ATOM   1859  C  C     . PRO A 1 242 ? -60.449 -12.131 -10.916  1.00 37.93  ? 242 PRO A C     1 
ATOM   1860  O  O     . PRO A 1 242 ? -61.608 -12.544 -10.987  1.00 38.34  ? 242 PRO A O     1 
ATOM   1861  C  CB    . PRO A 1 242 ? -58.821 -13.708 -9.661   1.00 40.64  ? 242 PRO A CB    1 
ATOM   1862  C  CG    . PRO A 1 242 ? -59.842 -14.709 -9.192   1.00 39.89  ? 242 PRO A CG    1 
ATOM   1863  C  CD    . PRO A 1 242 ? -60.770 -13.962 -8.248   1.00 38.86  ? 242 PRO A CD    1 
ATOM   1864  N  N     . TYR A 1 243 ? -59.883 -11.394 -11.872  1.00 36.57  ? 243 TYR A N     1 
ATOM   1865  C  CA    . TYR A 1 243 ? -60.594 -11.063 -13.092  1.00 34.40  ? 243 TYR A CA    1 
ATOM   1866  C  C     . TYR A 1 243 ? -59.660 -11.135 -14.296  1.00 35.83  ? 243 TYR A C     1 
ATOM   1867  O  O     . TYR A 1 243 ? -58.427 -11.086 -14.172  1.00 37.61  ? 243 TYR A O     1 
ATOM   1868  C  CB    . TYR A 1 243 ? -61.243 -9.680  -12.951  1.00 40.61  ? 243 TYR A CB    1 
ATOM   1869  C  CG    . TYR A 1 243 ? -60.292 -8.537  -12.684  1.00 40.16  ? 243 TYR A CG    1 
ATOM   1870  C  CD1   . TYR A 1 243 ? -59.501 -8.010  -13.691  1.00 43.60  ? 243 TYR A CD1   1 
ATOM   1871  C  CD2   . TYR A 1 243 ? -60.169 -7.987  -11.419  1.00 40.92  ? 243 TYR A CD2   1 
ATOM   1872  C  CE1   . TYR A 1 243 ? -58.606 -6.982  -13.447  1.00 41.72  ? 243 TYR A CE1   1 
ATOM   1873  C  CE2   . TYR A 1 243 ? -59.272 -6.961  -11.155  1.00 39.73  ? 243 TYR A CE2   1 
ATOM   1874  C  CZ    . TYR A 1 243 ? -58.496 -6.447  -12.175  1.00 40.69  ? 243 TYR A CZ    1 
ATOM   1875  O  OH    . TYR A 1 243 ? -57.633 -5.407  -11.930  1.00 39.73  ? 243 TYR A OH    1 
ATOM   1876  N  N     . LEU A 1 244 ? -60.287 -11.202 -15.471  1.00 34.90  ? 244 LEU A N     1 
ATOM   1877  C  CA    . LEU A 1 244 ? -59.605 -11.121 -16.751  1.00 37.06  ? 244 LEU A CA    1 
ATOM   1878  C  C     . LEU A 1 244 ? -60.379 -10.157 -17.632  1.00 39.50  ? 244 LEU A C     1 
ATOM   1879  O  O     . LEU A 1 244 ? -61.608 -10.225 -17.685  1.00 40.58  ? 244 LEU A O     1 
ATOM   1880  C  CB    . LEU A 1 244 ? -59.561 -12.517 -17.371  1.00 38.37  ? 244 LEU A CB    1 
ATOM   1881  C  CG    . LEU A 1 244 ? -59.296 -12.578 -18.868  1.00 38.54  ? 244 LEU A CG    1 
ATOM   1882  C  CD1   . LEU A 1 244 ? -57.954 -11.980 -19.212  1.00 36.42  ? 244 LEU A CD1   1 
ATOM   1883  C  CD2   . LEU A 1 244 ? -59.373 -14.027 -19.348  1.00 47.86  ? 244 LEU A CD2   1 
ATOM   1884  N  N     . ILE A 1 245 ? -59.661 -9.219  -18.249  1.00 35.04  ? 245 ILE A N     1 
ATOM   1885  C  CA    . ILE A 1 245 ? -60.274 -8.302  -19.199  1.00 36.31  ? 245 ILE A CA    1 
ATOM   1886  C  C     . ILE A 1 245 ? -59.569 -8.511  -20.525  1.00 37.67  ? 245 ILE A C     1 
ATOM   1887  O  O     . ILE A 1 245 ? -58.336 -8.499  -20.572  1.00 41.15  ? 245 ILE A O     1 
ATOM   1888  C  CB    . ILE A 1 245 ? -60.155 -6.842  -18.724  1.00 39.07  ? 245 ILE A CB    1 
ATOM   1889  C  CG1   . ILE A 1 245 ? -60.674 -6.672  -17.289  1.00 39.14  ? 245 ILE A CG1   1 
ATOM   1890  C  CG2   . ILE A 1 245 ? -60.838 -5.922  -19.724  1.00 39.19  ? 245 ILE A CG2   1 
ATOM   1891  C  CD1   . ILE A 1 245 ? -60.614 -5.237  -16.762  1.00 43.67  ? 245 ILE A CD1   1 
ATOM   1892  N  N     . THR A 1 246 ? -60.345 -8.804  -21.572  1.00 40.03  ? 246 THR A N     1 
ATOM   1893  C  CA    . THR A 1 246 ? -59.771 -9.138  -22.863  1.00 38.61  ? 246 THR A CA    1 
ATOM   1894  C  C     . THR A 1 246 ? -59.960 -7.956  -23.805  1.00 37.95  ? 246 THR A C     1 
ATOM   1895  O  O     . THR A 1 246 ? -60.957 -7.250  -23.715  1.00 36.71  ? 246 THR A O     1 
ATOM   1896  C  CB    . THR A 1 246 ? -60.348 -10.429 -23.479  1.00 38.93  ? 246 THR A CB    1 
ATOM   1897  O  OG1   . THR A 1 246 ? -61.746 -10.276 -23.720  1.00 39.08  ? 246 THR A OG1   1 
ATOM   1898  C  CG2   . THR A 1 246 ? -60.114 -11.655 -22.627  1.00 37.20  ? 246 THR A CG2   1 
ATOM   1899  N  N     . PHE A 1 247 ? -58.984 -7.765  -24.707  1.00 38.83  ? 247 PHE A N     1 
ATOM   1900  C  CA    . PHE A 1 247 ? -59.082 -6.785  -25.778  1.00 41.69  ? 247 PHE A CA    1 
ATOM   1901  C  C     . PHE A 1 247 ? -58.794 -7.490  -27.100  1.00 40.04  ? 247 PHE A C     1 
ATOM   1902  O  O     . PHE A 1 247 ? -57.837 -8.265  -27.186  1.00 42.13  ? 247 PHE A O     1 
ATOM   1903  C  CB    . PHE A 1 247 ? -58.131 -5.608  -25.522  1.00 39.67  ? 247 PHE A CB    1 
ATOM   1904  C  CG    . PHE A 1 247 ? -58.250 -5.038  -24.133  1.00 42.17  ? 247 PHE A CG    1 
ATOM   1905  C  CD1   . PHE A 1 247 ? -59.280 -4.174  -23.805  1.00 43.79  ? 247 PHE A CD1   1 
ATOM   1906  C  CD2   . PHE A 1 247 ? -57.375 -5.432  -23.130  1.00 45.53  ? 247 PHE A CD2   1 
ATOM   1907  C  CE1   . PHE A 1 247 ? -59.407 -3.681  -22.514  1.00 42.71  ? 247 PHE A CE1   1 
ATOM   1908  C  CE2   . PHE A 1 247 ? -57.508 -4.945  -21.837  1.00 41.80  ? 247 PHE A CE2   1 
ATOM   1909  C  CZ    . PHE A 1 247 ? -58.525 -4.076  -21.531  1.00 41.30  ? 247 PHE A CZ    1 
ATOM   1910  N  N     . GLU A 1 248 ? -59.613 -7.177  -28.119  1.00 43.10  ? 248 GLU A N     1 
ATOM   1911  C  CA    . GLU A 1 248 ? -59.645 -7.899  -29.392  1.00 42.54  ? 248 GLU A CA    1 
ATOM   1912  C  C     . GLU A 1 248 ? -58.557 -7.433  -30.367  1.00 40.84  ? 248 GLU A C     1 
ATOM   1913  O  O     . GLU A 1 248 ? -58.136 -8.211  -31.210  1.00 43.77  ? 248 GLU A O     1 
ATOM   1914  C  CB    . GLU A 1 248 ? -61.004 -7.718  -30.070  1.00 43.10  ? 248 GLU A CB    1 
ATOM   1915  C  CG    . GLU A 1 248 ? -62.168 -8.355  -29.325  1.00 58.10  ? 248 GLU A CG    1 
ATOM   1916  C  CD    . GLU A 1 248 ? -62.262 -9.881  -29.381  1.00 67.61  ? 248 GLU A CD    1 
ATOM   1917  O  OE1   . GLU A 1 248 ? -62.183 -10.411 -30.500  1.00 81.26  ? 248 GLU A OE1   1 
ATOM   1918  O  OE2   . GLU A 1 248 ? -62.450 -10.548 -28.312  1.00 54.57  ? 248 GLU A OE2   1 
ATOM   1919  N  N     . ASN A 1 249 ? -58.082 -6.182  -30.274  1.00 42.72  ? 249 ASN A N     1 
ATOM   1920  C  CA    . ASN A 1 249 ? -57.224 -5.610  -31.315  1.00 40.96  ? 249 ASN A CA    1 
ATOM   1921  C  C     . ASN A 1 249 ? -55.811 -5.369  -30.803  1.00 41.95  ? 249 ASN A C     1 
ATOM   1922  O  O     . ASN A 1 249 ? -55.628 -4.892  -29.685  1.00 43.27  ? 249 ASN A O     1 
ATOM   1923  C  CB    . ASN A 1 249 ? -57.766 -4.277  -31.811  1.00 40.01  ? 249 ASN A CB    1 
ATOM   1924  C  CG    . ASN A 1 249 ? -59.125 -4.455  -32.441  1.00 43.83  ? 249 ASN A CG    1 
ATOM   1925  O  OD1   . ASN A 1 249 ? -59.228 -5.106  -33.468  1.00 50.09  ? 249 ASN A OD1   1 
ATOM   1926  N  ND2   . ASN A 1 249 ? -60.171 -3.948  -31.813  1.00 47.67  ? 249 ASN A ND2   1 
ATOM   1927  N  N     . GLU A 1 250 ? -54.810 -5.645  -31.643  1.00 40.49  ? 250 GLU A N     1 
ATOM   1928  C  CA    . GLU A 1 250 ? -53.426 -5.497  -31.226  1.00 40.68  ? 250 GLU A CA    1 
ATOM   1929  C  C     . GLU A 1 250 ? -53.115 -4.046  -30.835  1.00 45.10  ? 250 GLU A C     1 
ATOM   1930  O  O     . GLU A 1 250 ? -52.321 -3.822  -29.912  1.00 47.14  ? 250 GLU A O     1 
ATOM   1931  C  CB    . GLU A 1 250 ? -52.476 -6.006  -32.306  1.00 48.45  ? 250 GLU A CB    1 
ATOM   1932  C  CG    . GLU A 1 250 ? -52.503 -5.169  -33.563  1.00 50.57  ? 250 GLU A CG    1 
ATOM   1933  C  CD    . GLU A 1 250 ? -51.463 -5.551  -34.598  1.00 56.35  ? 250 GLU A CD    1 
ATOM   1934  O  OE1   . GLU A 1 250 ? -50.663 -6.480  -34.327  1.00 57.04  ? 250 GLU A OE1   1 
ATOM   1935  O  OE2   . GLU A 1 250 ? -51.449 -4.902  -35.663  1.00 64.07  ? 250 GLU A OE2   1 
ATOM   1936  N  N     . ASP A 1 251 ? -53.784 -3.072  -31.476  1.00 40.32  ? 251 ASP A N     1 
ATOM   1937  C  CA    . ASP A 1 251 ? -53.551 -1.649  -31.221  1.00 44.84  ? 251 ASP A CA    1 
ATOM   1938  C  C     . ASP A 1 251 ? -54.260 -1.157  -29.955  1.00 43.10  ? 251 ASP A C     1 
ATOM   1939  O  O     . ASP A 1 251 ? -53.996 -0.047  -29.512  1.00 46.93  ? 251 ASP A O     1 
ATOM   1940  C  CB    . ASP A 1 251 ? -53.884 -0.801  -32.456  1.00 47.98  ? 251 ASP A CB    1 
ATOM   1941  C  CG    . ASP A 1 251 ? -52.775 -0.840  -33.511  1.00 51.79  ? 251 ASP A CG    1 
ATOM   1942  O  OD1   . ASP A 1 251 ? -51.811 -1.593  -33.327  1.00 54.27  ? 251 ASP A OD1   1 
ATOM   1943  O  OD2   . ASP A 1 251 ? -52.864 -0.096  -34.493  1.00 62.44  ? 251 ASP A OD2   1 
ATOM   1944  N  N     . ASP A 1 252 ? -55.084 -1.995  -29.311  1.00 41.62  ? 252 ASP A N     1 
ATOM   1945  C  CA    . ASP A 1 252 ? -55.794 -1.605  -28.101  1.00 41.98  ? 252 ASP A CA    1 
ATOM   1946  C  C     . ASP A 1 252 ? -54.816 -1.363  -26.945  1.00 39.68  ? 252 ASP A C     1 
ATOM   1947  O  O     . ASP A 1 252 ? -55.113 -0.634  -26.019  1.00 39.55  ? 252 ASP A O     1 
ATOM   1948  C  CB    . ASP A 1 252 ? -56.829 -2.670  -27.708  1.00 48.64  ? 252 ASP A CB    1 
ATOM   1949  C  CG    . ASP A 1 252 ? -58.123 -2.663  -28.521  1.00 50.31  ? 252 ASP A CG    1 
ATOM   1950  O  OD1   . ASP A 1 252 ? -58.411 -1.638  -29.143  1.00 39.28  ? 252 ASP A OD1   1 
ATOM   1951  O  OD2   . ASP A 1 252 ? -58.865 -3.707  -28.501  1.00 46.78  ? 252 ASP A OD2   1 
ATOM   1952  N  N     . ILE A 1 253 ? -53.628 -1.955  -26.984  1.00 40.61  ? 253 ILE A N     1 
ATOM   1953  C  CA    . ILE A 1 253 ? -52.719 -1.860  -25.857  1.00 40.55  ? 253 ILE A CA    1 
ATOM   1954  C  C     . ILE A 1 253 ? -52.316 -0.405  -25.586  1.00 37.61  ? 253 ILE A C     1 
ATOM   1955  O  O     . ILE A 1 253 ? -51.969 -0.077  -24.461  1.00 37.96  ? 253 ILE A O     1 
ATOM   1956  C  CB    . ILE A 1 253 ? -51.516 -2.784  -26.080  1.00 39.24  ? 253 ILE A CB    1 
ATOM   1957  C  CG1   . ILE A 1 253 ? -50.643 -2.911  -24.829  1.00 45.22  ? 253 ILE A CG1   1 
ATOM   1958  C  CG2   . ILE A 1 253 ? -50.696 -2.355  -27.293  1.00 44.75  ? 253 ILE A CG2   1 
ATOM   1959  C  CD1   . ILE A 1 253 ? -51.346 -3.496  -23.642  1.00 46.15  ? 253 ILE A CD1   1 
ATOM   1960  N  N     . GLU A 1 254 ? -52.360 0.462   -26.601  1.00 39.53  ? 254 GLU A N     1 
ATOM   1961  C  CA    . GLU A 1 254 ? -52.076 1.883   -26.415  1.00 39.98  ? 254 GLU A CA    1 
ATOM   1962  C  C     . GLU A 1 254 ? -53.058 2.504   -25.421  1.00 38.84  ? 254 GLU A C     1 
ATOM   1963  O  O     . GLU A 1 254 ? -52.636 3.027   -24.401  1.00 42.01  ? 254 GLU A O     1 
ATOM   1964  C  CB    . GLU A 1 254 ? -52.096 2.623   -27.756  1.00 42.23  ? 254 GLU A CB    1 
ATOM   1965  C  CG    . GLU A 1 254 ? -51.778 4.111   -27.647  1.00 46.61  ? 254 GLU A CG    1 
ATOM   1966  C  CD    . GLU A 1 254 ? -51.440 4.863   -28.925  1.00 46.58  ? 254 GLU A CD    1 
ATOM   1967  O  OE1   . GLU A 1 254 ? -51.488 4.279   -30.006  1.00 53.02  ? 254 GLU A OE1   1 
ATOM   1968  O  OE2   . GLU A 1 254 ? -51.084 6.036   -28.820  1.00 57.51  ? 254 GLU A OE2   1 
ATOM   1969  N  N     . THR A 1 255 ? -54.359 2.474   -25.722  1.00 36.09  ? 255 THR A N     1 
ATOM   1970  C  CA    . THR A 1 255 ? -55.348 3.115   -24.859  1.00 39.43  ? 255 THR A CA    1 
ATOM   1971  C  C     . THR A 1 255 ? -55.473 2.370   -23.523  1.00 40.74  ? 255 THR A C     1 
ATOM   1972  O  O     . THR A 1 255 ? -55.682 2.996   -22.468  1.00 39.18  ? 255 THR A O     1 
ATOM   1973  C  CB    . THR A 1 255 ? -56.691 3.262   -25.593  1.00 39.73  ? 255 THR A CB    1 
ATOM   1974  O  OG1   . THR A 1 255 ? -57.588 4.019   -24.782  1.00 39.83  ? 255 THR A OG1   1 
ATOM   1975  C  CG2   . THR A 1 255 ? -57.353 1.935   -25.906  1.00 44.58  ? 255 THR A CG2   1 
ATOM   1976  N  N     . VAL A 1 256 ? -55.304 1.038   -23.567  1.00 37.05  ? 256 VAL A N     1 
ATOM   1977  C  CA    . VAL A 1 256 ? -55.300 0.209   -22.373  1.00 38.43  ? 256 VAL A CA    1 
ATOM   1978  C  C     . VAL A 1 256 ? -54.225 0.672   -21.389  1.00 38.49  ? 256 VAL A C     1 
ATOM   1979  O  O     . VAL A 1 256 ? -54.503 0.821   -20.195  1.00 36.81  ? 256 VAL A O     1 
ATOM   1980  C  CB    . VAL A 1 256 ? -55.137 -1.287  -22.721  1.00 39.58  ? 256 VAL A CB    1 
ATOM   1981  C  CG1   . VAL A 1 256 ? -54.777 -2.115  -21.497  1.00 38.26  ? 256 VAL A CG1   1 
ATOM   1982  C  CG2   . VAL A 1 256 ? -56.411 -1.848  -23.353  1.00 42.28  ? 256 VAL A CG2   1 
ATOM   1983  N  N     . THR A 1 257 ? -53.001 0.880   -21.892  1.00 36.71  ? 257 THR A N     1 
ATOM   1984  C  CA    . THR A 1 257 ? -51.916 1.362   -21.054  1.00 37.10  ? 257 THR A CA    1 
ATOM   1985  C  C     . THR A 1 257 ? -52.214 2.757   -20.511  1.00 37.59  ? 257 THR A C     1 
ATOM   1986  O  O     . THR A 1 257 ? -51.946 2.990   -19.337  1.00 40.93  ? 257 THR A O     1 
ATOM   1987  C  CB    . THR A 1 257 ? -50.583 1.325   -21.789  1.00 38.05  ? 257 THR A CB    1 
ATOM   1988  O  OG1   . THR A 1 257 ? -50.456 -0.024  -22.225  1.00 40.94  ? 257 THR A OG1   1 
ATOM   1989  C  CG2   . THR A 1 257 ? -49.428 1.722   -20.894  1.00 40.91  ? 257 THR A CG2   1 
ATOM   1990  N  N     . GLU A 1 258 ? -52.758 3.659   -21.344  1.00 35.82  ? 258 GLU A N     1 
ATOM   1991  C  CA    . GLU A 1 258 ? -53.161 4.989   -20.885  1.00 39.52  ? 258 GLU A CA    1 
ATOM   1992  C  C     . GLU A 1 258 ? -54.159 4.891   -19.722  1.00 41.56  ? 258 GLU A C     1 
ATOM   1993  O  O     . GLU A 1 258 ? -54.091 5.664   -18.772  1.00 37.93  ? 258 GLU A O     1 
ATOM   1994  C  CB    . GLU A 1 258 ? -53.821 5.790   -22.014  1.00 41.58  ? 258 GLU A CB    1 
ATOM   1995  C  CG    . GLU A 1 258 ? -52.839 6.330   -23.025  1.00 41.19  ? 258 GLU A CG    1 
ATOM   1996  C  CD    . GLU A 1 258 ? -51.826 7.263   -22.403  1.00 42.10  ? 258 GLU A CD    1 
ATOM   1997  O  OE1   . GLU A 1 258 ? -52.257 8.344   -21.927  1.00 44.90  ? 258 GLU A OE1   1 
ATOM   1998  O  OE2   . GLU A 1 258 ? -50.630 6.874   -22.327  1.00 41.61  ? 258 GLU A OE2   1 
ATOM   1999  N  N     . ARG A 1 259 ? -55.101 3.942   -19.787  1.00 42.99  ? 259 ARG A N     1 
ATOM   2000  C  CA    . ARG A 1 259 ? -56.149 3.825   -18.777  1.00 40.44  ? 259 ARG A CA    1 
ATOM   2001  C  C     . ARG A 1 259 ? -55.619 3.151   -17.512  1.00 40.61  ? 259 ARG A C     1 
ATOM   2002  O  O     . ARG A 1 259 ? -56.055 3.446   -16.400  1.00 35.23  ? 259 ARG A O     1 
ATOM   2003  C  CB    . ARG A 1 259 ? -57.314 3.030   -19.359  1.00 41.99  ? 259 ARG A CB    1 
ATOM   2004  C  CG    . ARG A 1 259 ? -58.011 3.761   -20.490  1.00 46.25  ? 259 ARG A CG    1 
ATOM   2005  C  CD    . ARG A 1 259 ? -58.594 2.769   -21.476  1.00 51.43  ? 259 ARG A CD    1 
ATOM   2006  N  NE    . ARG A 1 259 ? -59.125 3.422   -22.663  1.00 50.38  ? 259 ARG A NE    1 
ATOM   2007  C  CZ    . ARG A 1 259 ? -60.416 3.646   -22.884  1.00 49.14  ? 259 ARG A CZ    1 
ATOM   2008  N  NH1   . ARG A 1 259 ? -61.327 3.389   -21.959  1.00 43.82  ? 259 ARG A NH1   1 
ATOM   2009  N  NH2   . ARG A 1 259 ? -60.787 4.132   -24.048  1.00 53.04  ? 259 ARG A NH2   1 
ATOM   2010  N  N     . LEU A 1 260 ? -54.664 2.232   -17.688  1.00 38.24  ? 260 LEU A N     1 
ATOM   2011  C  CA    . LEU A 1 260 ? -54.091 1.543   -16.554  1.00 38.63  ? 260 LEU A CA    1 
ATOM   2012  C  C     . LEU A 1 260 ? -53.306 2.530   -15.681  1.00 41.15  ? 260 LEU A C     1 
ATOM   2013  O  O     . LEU A 1 260 ? -53.204 2.318   -14.468  1.00 38.45  ? 260 LEU A O     1 
ATOM   2014  C  CB    . LEU A 1 260 ? -53.189 0.413   -17.068  1.00 39.89  ? 260 LEU A CB    1 
ATOM   2015  C  CG    . LEU A 1 260 ? -53.893 -0.899  -17.425  1.00 38.68  ? 260 LEU A CG    1 
ATOM   2016  C  CD1   . LEU A 1 260 ? -52.924 -1.871  -18.094  1.00 38.61  ? 260 LEU A CD1   1 
ATOM   2017  C  CD2   . LEU A 1 260 ? -54.495 -1.543  -16.195  1.00 39.33  ? 260 LEU A CD2   1 
ATOM   2018  N  N     . ARG A 1 261 ? -52.735 3.580   -16.297  1.00 41.27  ? 261 ARG A N     1 
ATOM   2019  C  CA    . ARG A 1 261 ? -51.767 4.434   -15.613  1.00 42.50  ? 261 ARG A CA    1 
ATOM   2020  C  C     . ARG A 1 261 ? -52.351 5.003   -14.323  1.00 36.96  ? 261 ARG A C     1 
ATOM   2021  O  O     . ARG A 1 261 ? -51.797 4.751   -13.257  1.00 36.94  ? 261 ARG A O     1 
ATOM   2022  C  CB    . ARG A 1 261 ? -51.251 5.580   -16.494  1.00 45.49  ? 261 ARG A CB    1 
ATOM   2023  C  CG    . ARG A 1 261 ? -50.410 6.612   -15.743  1.00 43.73  ? 261 ARG A CG    1 
ATOM   2024  C  CD    . ARG A 1 261 ? -49.747 7.660   -16.621  1.00 44.27  ? 261 ARG A CD    1 
ATOM   2025  N  NE    . ARG A 1 261 ? -50.742 8.374   -17.405  1.00 42.50  ? 261 ARG A NE    1 
ATOM   2026  C  CZ    . ARG A 1 261 ? -50.907 8.276   -18.723  1.00 44.23  ? 261 ARG A CZ    1 
ATOM   2027  N  NH1   . ARG A 1 261 ? -50.162 7.467   -19.469  1.00 43.10  ? 261 ARG A NH1   1 
ATOM   2028  N  NH2   . ARG A 1 261 ? -51.852 8.988   -19.295  1.00 38.10  ? 261 ARG A NH2   1 
ATOM   2029  N  N     . PRO A 1 262 ? -53.446 5.797   -14.344  1.00 38.52  ? 262 PRO A N     1 
ATOM   2030  C  CA    . PRO A 1 262 ? -53.978 6.370   -13.103  1.00 37.55  ? 262 PRO A CA    1 
ATOM   2031  C  C     . PRO A 1 262 ? -54.438 5.302   -12.112  1.00 37.91  ? 262 PRO A C     1 
ATOM   2032  O  O     . PRO A 1 262 ? -54.347 5.505   -10.906  1.00 36.43  ? 262 PRO A O     1 
ATOM   2033  C  CB    . PRO A 1 262 ? -55.143 7.261   -13.568  1.00 38.80  ? 262 PRO A CB    1 
ATOM   2034  C  CG    . PRO A 1 262 ? -55.508 6.703   -14.939  1.00 40.07  ? 262 PRO A CG    1 
ATOM   2035  C  CD    . PRO A 1 262 ? -54.186 6.258   -15.530  1.00 39.62  ? 262 PRO A CD    1 
ATOM   2036  N  N     . LEU A 1 263 ? -54.900 4.146   -12.615  1.00 40.04  ? 263 LEU A N     1 
ATOM   2037  C  CA    . LEU A 1 263 ? -55.364 3.060   -11.759  1.00 38.20  ? 263 LEU A CA    1 
ATOM   2038  C  C     . LEU A 1 263 ? -54.213 2.493   -10.940  1.00 35.12  ? 263 LEU A C     1 
ATOM   2039  O  O     . LEU A 1 263 ? -54.404 2.153   -9.771   1.00 35.70  ? 263 LEU A O     1 
ATOM   2040  C  CB    . LEU A 1 263 ? -55.997 1.950   -12.608  1.00 43.91  ? 263 LEU A CB    1 
ATOM   2041  C  CG    . LEU A 1 263 ? -57.303 2.305   -13.317  1.00 42.60  ? 263 LEU A CG    1 
ATOM   2042  C  CD1   . LEU A 1 263 ? -57.772 1.141   -14.183  1.00 44.79  ? 263 LEU A CD1   1 
ATOM   2043  C  CD2   . LEU A 1 263 ? -58.402 2.692   -12.332  1.00 41.58  ? 263 LEU A CD2   1 
ATOM   2044  N  N     . LYS A 1 264 ? -53.034 2.351   -11.571  1.00 35.50  ? 264 LYS A N     1 
ATOM   2045  C  CA    . LYS A 1 264 ? -51.877 1.793   -10.892  1.00 34.63  ? 264 LYS A CA    1 
ATOM   2046  C  C     . LYS A 1 264 ? -51.254 2.822   -9.949   1.00 37.16  ? 264 LYS A C     1 
ATOM   2047  O  O     . LYS A 1 264 ? -50.949 2.511   -8.804   1.00 40.48  ? 264 LYS A O     1 
ATOM   2048  C  CB    . LYS A 1 264 ? -50.863 1.231   -11.896  1.00 35.24  ? 264 LYS A CB    1 
ATOM   2049  C  CG    . LYS A 1 264 ? -51.182 -0.177  -12.402  1.00 39.85  ? 264 LYS A CG    1 
ATOM   2050  C  CD    . LYS A 1 264 ? -51.330 -1.210  -11.296  1.00 41.05  ? 264 LYS A CD    1 
ATOM   2051  C  CE    . LYS A 1 264 ? -50.046 -1.492  -10.549  1.00 48.07  ? 264 LYS A CE    1 
ATOM   2052  N  NZ    . LYS A 1 264 ? -50.294 -2.093  -9.214   1.00 54.05  ? 264 LYS A NZ    1 
ATOM   2053  N  N     . VAL A 1 265 ? -51.066 4.058   -10.417  1.00 40.87  ? 265 VAL A N     1 
ATOM   2054  C  CA    . VAL A 1 265 ? -50.387 5.068   -9.615   1.00 37.10  ? 265 VAL A CA    1 
ATOM   2055  C  C     . VAL A 1 265 ? -51.152 5.274   -8.301   1.00 37.72  ? 265 VAL A C     1 
ATOM   2056  O  O     . VAL A 1 265 ? -50.557 5.341   -7.228   1.00 36.25  ? 265 VAL A O     1 
ATOM   2057  C  CB    . VAL A 1 265 ? -50.212 6.374   -10.417  1.00 39.35  ? 265 VAL A CB    1 
ATOM   2058  C  CG1   . VAL A 1 265 ? -49.625 7.487   -9.565   1.00 41.11  ? 265 VAL A CG1   1 
ATOM   2059  C  CG2   . VAL A 1 265 ? -49.354 6.183   -11.653  1.00 40.13  ? 265 VAL A CG2   1 
ATOM   2060  N  N     . ALA A 1 266 ? -52.486 5.338   -8.374   1.00 33.04  ? 266 ALA A N     1 
ATOM   2061  C  CA    . ALA A 1 266 ? -53.300 5.547   -7.194   1.00 35.58  ? 266 ALA A CA    1 
ATOM   2062  C  C     . ALA A 1 266 ? -53.530 4.253   -6.416   1.00 40.34  ? 266 ALA A C     1 
ATOM   2063  O  O     . ALA A 1 266 ? -54.091 4.315   -5.329   1.00 43.80  ? 266 ALA A O     1 
ATOM   2064  C  CB    . ALA A 1 266 ? -54.623 6.176   -7.576   1.00 34.63  ? 266 ALA A CB    1 
ATOM   2065  N  N     . GLY A 1 267 ? -53.129 3.093   -6.958   1.00 39.98  ? 267 GLY A N     1 
ATOM   2066  C  CA    . GLY A 1 267 ? -53.272 1.829   -6.256   1.00 37.35  ? 267 GLY A CA    1 
ATOM   2067  C  C     . GLY A 1 267 ? -54.718 1.316   -6.237   1.00 40.92  ? 267 GLY A C     1 
ATOM   2068  O  O     . GLY A 1 267 ? -55.093 0.520   -5.387   1.00 43.24  ? 267 GLY A O     1 
ATOM   2069  N  N     . VAL A 1 268 ? -55.523 1.698   -7.222   1.00 39.00  ? 268 VAL A N     1 
ATOM   2070  C  CA    . VAL A 1 268 ? -56.878 1.186   -7.331   1.00 38.22  ? 268 VAL A CA    1 
ATOM   2071  C  C     . VAL A 1 268 ? -56.795 -0.304  -7.696   1.00 39.21  ? 268 VAL A C     1 
ATOM   2072  O  O     . VAL A 1 268 ? -57.609 -1.110  -7.283   1.00 40.30  ? 268 VAL A O     1 
ATOM   2073  C  CB    . VAL A 1 268 ? -57.653 1.996   -8.382   1.00 41.35  ? 268 VAL A CB    1 
ATOM   2074  C  CG1   . VAL A 1 268 ? -59.052 1.444   -8.626   1.00 46.89  ? 268 VAL A CG1   1 
ATOM   2075  C  CG2   . VAL A 1 268 ? -57.717 3.476   -8.016   1.00 44.28  ? 268 VAL A CG2   1 
ATOM   2076  N  N     . ILE A 1 269 ? -55.829 -0.633  -8.549   1.00 39.57  ? 269 ILE A N     1 
ATOM   2077  C  CA    . ILE A 1 269 ? -55.423 -1.997  -8.831   1.00 39.24  ? 269 ILE A CA    1 
ATOM   2078  C  C     . ILE A 1 269 ? -54.375 -2.371  -7.789   1.00 37.01  ? 269 ILE A C     1 
ATOM   2079  O  O     . ILE A 1 269 ? -53.307 -1.777  -7.734   1.00 36.87  ? 269 ILE A O     1 
ATOM   2080  C  CB    . ILE A 1 269 ? -54.896 -2.085  -10.277  1.00 41.77  ? 269 ILE A CB    1 
ATOM   2081  C  CG1   . ILE A 1 269 ? -56.023 -1.857  -11.295  1.00 39.86  ? 269 ILE A CG1   1 
ATOM   2082  C  CG2   . ILE A 1 269 ? -54.184 -3.413  -10.505  1.00 46.32  ? 269 ILE A CG2   1 
ATOM   2083  C  CD1   . ILE A 1 269 ? -55.568 -1.669  -12.723  1.00 35.12  ? 269 ILE A CD1   1 
ATOM   2084  N  N     . GLN A 1 270 ? -54.668 -3.390  -6.996   1.00 33.31  ? 270 GLN A N     1 
ATOM   2085  C  CA    . GLN A 1 270 ? -53.936 -3.651  -5.774   1.00 36.80  ? 270 GLN A CA    1 
ATOM   2086  C  C     . GLN A 1 270 ? -52.719 -4.540  -6.006   1.00 38.23  ? 270 GLN A C     1 
ATOM   2087  O  O     . GLN A 1 270 ? -51.851 -4.615  -5.139   1.00 36.93  ? 270 GLN A O     1 
ATOM   2088  C  CB    . GLN A 1 270 ? -54.887 -4.299  -4.780   1.00 38.59  ? 270 GLN A CB    1 
ATOM   2089  C  CG    . GLN A 1 270 ? -56.032 -3.370  -4.386   1.00 36.82  ? 270 GLN A CG    1 
ATOM   2090  C  CD    . GLN A 1 270 ? -57.210 -4.123  -3.831   1.00 39.27  ? 270 GLN A CD    1 
ATOM   2091  O  OE1   . GLN A 1 270 ? -57.940 -4.792  -4.559   1.00 41.63  ? 270 GLN A OE1   1 
ATOM   2092  N  NE2   . GLN A 1 270 ? -57.392 -4.020  -2.526   1.00 40.27  ? 270 GLN A NE2   1 
ATOM   2093  N  N     . ASN A 1 271 ? -52.680 -5.257  -7.134   1.00 38.06  ? 271 ASN A N     1 
ATOM   2094  C  CA    . ASN A 1 271 ? -51.545 -6.124  -7.428   1.00 37.75  ? 271 ASN A CA    1 
ATOM   2095  C  C     . ASN A 1 271 ? -50.881 -5.626  -8.708   1.00 38.18  ? 271 ASN A C     1 
ATOM   2096  O  O     . ASN A 1 271 ? -51.300 -4.603  -9.257   1.00 39.90  ? 271 ASN A O     1 
ATOM   2097  C  CB    . ASN A 1 271 ? -51.935 -7.608  -7.487   1.00 37.02  ? 271 ASN A CB    1 
ATOM   2098  C  CG    . ASN A 1 271 ? -52.998 -7.953  -8.516   1.00 39.20  ? 271 ASN A CG    1 
ATOM   2099  O  OD1   . ASN A 1 271 ? -53.823 -7.125  -8.907   1.00 38.66  ? 271 ASN A OD1   1 
ATOM   2100  N  ND2   . ASN A 1 271 ? -53.045 -9.221  -8.889   1.00 41.25  ? 271 ASN A ND2   1 
ATOM   2101  N  N     . GLY A 1 272 ? -49.827 -6.326  -9.158   1.00 33.85  ? 272 GLY A N     1 
ATOM   2102  C  CA    . GLY A 1 272 ? -49.245 -6.027  -10.454  1.00 39.02  ? 272 GLY A CA    1 
ATOM   2103  C  C     . GLY A 1 272 ? -50.312 -6.175  -11.543  1.00 41.98  ? 272 GLY A C     1 
ATOM   2104  O  O     . GLY A 1 272 ? -51.160 -7.041  -11.449  1.00 46.85  ? 272 GLY A O     1 
ATOM   2105  N  N     . ALA A 1 273 ? -50.350 -5.257  -12.502  1.00 43.07  ? 273 ALA A N     1 
ATOM   2106  C  CA    . ALA A 1 273 ? -51.126 -5.450  -13.713  1.00 41.83  ? 273 ALA A CA    1 
ATOM   2107  C  C     . ALA A 1 273 ? -50.274 -6.215  -14.712  1.00 47.94  ? 273 ALA A C     1 
ATOM   2108  O  O     . ALA A 1 273 ? -49.106 -5.874  -14.919  1.00 45.75  ? 273 ALA A O     1 
ATOM   2109  C  CB    . ALA A 1 273 ? -51.544 -4.124  -14.295  1.00 43.53  ? 273 ALA A CB    1 
ATOM   2110  N  N     . THR A 1 274 ? -50.862 -7.257  -15.301  1.00 46.65  ? 274 THR A N     1 
ATOM   2111  C  CA    . THR A 1 274 ? -50.213 -8.008  -16.363  1.00 44.47  ? 274 THR A CA    1 
ATOM   2112  C  C     . THR A 1 274 ? -51.196 -8.063  -17.528  1.00 41.31  ? 274 THR A C     1 
ATOM   2113  O  O     . THR A 1 274 ? -52.327 -8.516  -17.365  1.00 41.68  ? 274 THR A O     1 
ATOM   2114  C  CB    . THR A 1 274 ? -49.786 -9.394  -15.862  1.00 50.39  ? 274 THR A CB    1 
ATOM   2115  O  OG1   . THR A 1 274 ? -50.974 -10.156 -15.641  1.00 59.75  ? 274 THR A OG1   1 
ATOM   2116  C  CG2   . THR A 1 274 ? -48.982 -9.328  -14.583  1.00 57.52  ? 274 THR A CG2   1 
ATOM   2117  N  N     . VAL A 1 275 ? -50.773 -7.547  -18.676  1.00 37.92  ? 275 VAL A N     1 
ATOM   2118  C  CA    . VAL A 1 275 ? -51.545 -7.600  -19.900  1.00 39.86  ? 275 VAL A CA    1 
ATOM   2119  C  C     . VAL A 1 275 ? -50.747 -8.473  -20.870  1.00 40.80  ? 275 VAL A C     1 
ATOM   2120  O  O     . VAL A 1 275 ? -49.724 -8.034  -21.384  1.00 38.64  ? 275 VAL A O     1 
ATOM   2121  C  CB    . VAL A 1 275 ? -51.782 -6.193  -20.484  1.00 40.92  ? 275 VAL A CB    1 
ATOM   2122  C  CG1   . VAL A 1 275 ? -52.767 -6.253  -21.637  1.00 45.58  ? 275 VAL A CG1   1 
ATOM   2123  C  CG2   . VAL A 1 275 ? -52.233 -5.181  -19.432  1.00 38.35  ? 275 VAL A CG2   1 
ATOM   2124  N  N     . ARG A 1 276 ? -51.186 -9.720  -21.069  1.00 38.96  ? 276 ARG A N     1 
ATOM   2125  C  CA    . ARG A 1 276 ? -50.378 -10.714 -21.772  1.00 41.20  ? 276 ARG A CA    1 
ATOM   2126  C  C     . ARG A 1 276 ? -50.902 -10.833 -23.205  1.00 37.79  ? 276 ARG A C     1 
ATOM   2127  O  O     . ARG A 1 276 ? -52.102 -10.688 -23.421  1.00 39.71  ? 276 ARG A O     1 
ATOM   2128  C  CB    . ARG A 1 276 ? -50.378 -11.999 -20.932  1.00 43.91  ? 276 ARG A CB    1 
ATOM   2129  C  CG    . ARG A 1 276 ? -49.490 -11.904 -19.695  1.00 51.63  ? 276 ARG A CG    1 
ATOM   2130  C  CD    . ARG A 1 276 ? -49.740 -12.877 -18.555  1.00 57.84  ? 276 ARG A CD    1 
ATOM   2131  N  NE    . ARG A 1 276 ? -49.811 -14.252 -19.013  1.00 68.87  ? 276 ARG A NE    1 
ATOM   2132  C  CZ    . ARG A 1 276 ? -49.037 -15.250 -18.585  1.00 85.54  ? 276 ARG A CZ    1 
ATOM   2133  N  NH1   . ARG A 1 276 ? -48.058 -15.018 -17.726  1.00 79.01  ? 276 ARG A NH1   1 
ATOM   2134  N  NH2   . ARG A 1 276 ? -49.236 -16.480 -19.040  1.00 83.01  ? 276 ARG A NH2   1 
ATOM   2135  N  N     . SER A 1 277 ? -50.000 -11.007 -24.183  1.00 33.50  ? 277 SER A N     1 
ATOM   2136  C  CA    . SER A 1 277 ? -50.404 -11.202 -25.567  1.00 36.50  ? 277 SER A CA    1 
ATOM   2137  C  C     . SER A 1 277 ? -51.062 -12.573 -25.742  1.00 37.56  ? 277 SER A C     1 
ATOM   2138  O  O     . SER A 1 277 ? -50.826 -13.508 -24.970  1.00 37.24  ? 277 SER A O     1 
ATOM   2139  C  CB    . SER A 1 277 ? -49.240 -11.048 -26.535  1.00 35.10  ? 277 SER A CB    1 
ATOM   2140  O  OG    . SER A 1 277 ? -48.266 -12.064 -26.344  1.00 38.09  ? 277 SER A OG    1 
ATOM   2141  N  N     . LEU A 1 278 ? -51.850 -12.683 -26.808  1.00 40.07  ? 278 LEU A N     1 
ATOM   2142  C  CA    . LEU A 1 278 ? -52.577 -13.906 -27.137  1.00 40.60  ? 278 LEU A CA    1 
ATOM   2143  C  C     . LEU A 1 278 ? -51.737 -15.179 -27.021  1.00 38.28  ? 278 LEU A C     1 
ATOM   2144  O  O     . LEU A 1 278 ? -52.116 -16.107 -26.322  1.00 42.93  ? 278 LEU A O     1 
ATOM   2145  C  CB    . LEU A 1 278 ? -53.121 -13.739 -28.550  1.00 42.68  ? 278 LEU A CB    1 
ATOM   2146  C  CG    . LEU A 1 278 ? -53.784 -14.974 -29.139  1.00 43.27  ? 278 LEU A CG    1 
ATOM   2147  C  CD1   . LEU A 1 278 ? -54.968 -15.403 -28.282  1.00 44.22  ? 278 LEU A CD1   1 
ATOM   2148  C  CD2   . LEU A 1 278 ? -54.209 -14.668 -30.561  1.00 43.08  ? 278 LEU A CD2   1 
ATOM   2149  N  N     . VAL A 1 279 ? -50.582 -15.242 -27.684  1.00 40.41  ? 279 VAL A N     1 
ATOM   2150  C  CA    . VAL A 1 279 ? -49.847 -16.494 -27.729  1.00 40.26  ? 279 VAL A CA    1 
ATOM   2151  C  C     . VAL A 1 279 ? -49.293 -16.849 -26.352  1.00 41.63  ? 279 VAL A C     1 
ATOM   2152  O  O     . VAL A 1 279 ? -49.205 -18.021 -25.985  1.00 39.92  ? 279 VAL A O     1 
ATOM   2153  C  CB    . VAL A 1 279 ? -48.724 -16.463 -28.782  1.00 39.87  ? 279 VAL A CB    1 
ATOM   2154  C  CG1   . VAL A 1 279 ? -47.852 -17.715 -28.717  1.00 42.25  ? 279 VAL A CG1   1 
ATOM   2155  C  CG2   . VAL A 1 279 ? -49.275 -16.272 -30.175  1.00 39.60  ? 279 VAL A CG2   1 
ATOM   2156  N  N     . LEU A 1 280 ? -48.862 -15.845 -25.591  1.00 44.62  ? 280 LEU A N     1 
ATOM   2157  C  CA    . LEU A 1 280 ? -48.324 -16.133 -24.273  1.00 47.57  ? 280 LEU A CA    1 
ATOM   2158  C  C     . LEU A 1 280 ? -49.400 -16.761 -23.385  1.00 42.05  ? 280 LEU A C     1 
ATOM   2159  O  O     . LEU A 1 280 ? -49.098 -17.657 -22.604  1.00 38.15  ? 280 LEU A O     1 
ATOM   2160  C  CB    . LEU A 1 280 ? -47.758 -14.866 -23.629  1.00 48.75  ? 280 LEU A CB    1 
ATOM   2161  C  CG    . LEU A 1 280 ? -47.161 -15.091 -22.242  1.00 49.84  ? 280 LEU A CG    1 
ATOM   2162  C  CD1   . LEU A 1 280 ? -46.097 -16.183 -22.276  1.00 48.62  ? 280 LEU A CD1   1 
ATOM   2163  C  CD2   . LEU A 1 280 ? -46.582 -13.795 -21.701  1.00 49.91  ? 280 LEU A CD2   1 
ATOM   2164  N  N     . ASP A 1 281 ? -50.652 -16.331 -23.537  1.00 40.27  ? 281 ASP A N     1 
ATOM   2165  C  CA    . ASP A 1 281 ? -51.725 -16.875 -22.708  1.00 47.63  ? 281 ASP A CA    1 
ATOM   2166  C  C     . ASP A 1 281 ? -52.243 -18.208 -23.250  1.00 45.64  ? 281 ASP A C     1 
ATOM   2167  O  O     . ASP A 1 281 ? -52.443 -19.143 -22.468  1.00 39.87  ? 281 ASP A O     1 
ATOM   2168  C  CB    . ASP A 1 281 ? -52.839 -15.853 -22.525  1.00 48.28  ? 281 ASP A CB    1 
ATOM   2169  C  CG    . ASP A 1 281 ? -52.497 -14.894 -21.398  1.00 57.88  ? 281 ASP A CG    1 
ATOM   2170  O  OD1   . ASP A 1 281 ? -51.606 -15.247 -20.584  1.00 61.71  ? 281 ASP A OD1   1 
ATOM   2171  O  OD2   . ASP A 1 281 ? -53.099 -13.804 -21.347  1.00 64.00  ? 281 ASP A OD2   1 
ATOM   2172  N  N     . ALA A 1 282 ? -52.445 -18.277 -24.580  1.00 45.39  ? 282 ALA A N     1 
ATOM   2173  C  CA    . ALA A 1 282 ? -52.782 -19.517 -25.276  1.00 42.86  ? 282 ALA A CA    1 
ATOM   2174  C  C     . ALA A 1 282 ? -51.882 -20.662 -24.845  1.00 40.90  ? 282 ALA A C     1 
ATOM   2175  O  O     . ALA A 1 282 ? -52.383 -21.760 -24.620  1.00 41.71  ? 282 ALA A O     1 
ATOM   2176  C  CB    . ALA A 1 282 ? -52.697 -19.342 -26.773  1.00 43.24  ? 282 ALA A CB    1 
ATOM   2177  N  N     . ALA A 1 283 ? -50.561 -20.405 -24.778  1.00 39.83  ? 283 ALA A N     1 
ATOM   2178  C  CA    . ALA A 1 283 ? -49.569 -21.460 -24.602  1.00 39.18  ? 283 ALA A CA    1 
ATOM   2179  C  C     . ALA A 1 283 ? -49.601 -22.049 -23.195  1.00 38.32  ? 283 ALA A C     1 
ATOM   2180  O  O     . ALA A 1 283 ? -48.862 -22.979 -22.903  1.00 38.20  ? 283 ALA A O     1 
ATOM   2181  C  CB    . ALA A 1 283 ? -48.190 -20.918 -24.934  1.00 41.98  ? 283 ALA A CB    1 
ATOM   2182  N  N     . ILE A 1 284 ? -50.437 -21.487 -22.308  1.00 43.61  ? 284 ILE A N     1 
ATOM   2183  C  CA    . ILE A 1 284 ? -50.690 -22.107 -21.017  1.00 43.15  ? 284 ILE A CA    1 
ATOM   2184  C  C     . ILE A 1 284 ? -51.556 -23.354 -21.215  1.00 43.87  ? 284 ILE A C     1 
ATOM   2185  O  O     . ILE A 1 284 ? -51.359 -24.320 -20.494  1.00 44.66  ? 284 ILE A O     1 
ATOM   2186  C  CB    . ILE A 1 284 ? -51.301 -21.124 -19.996  1.00 45.40  ? 284 ILE A CB    1 
ATOM   2187  C  CG1   . ILE A 1 284 ? -50.453 -19.861 -19.812  1.00 43.00  ? 284 ILE A CG1   1 
ATOM   2188  C  CG2   . ILE A 1 284 ? -51.520 -21.822 -18.664  1.00 47.93  ? 284 ILE A CG2   1 
ATOM   2189  C  CD1   . ILE A 1 284 ? -49.011 -20.146 -19.455  1.00 46.66  ? 284 ILE A CD1   1 
ATOM   2190  N  N     . THR A 1 285 ? -52.443 -23.364 -22.222  1.00 40.66  ? 285 THR A N     1 
ATOM   2191  C  CA    . THR A 1 285 ? -53.369 -24.475 -22.407  1.00 42.99  ? 285 THR A CA    1 
ATOM   2192  C  C     . THR A 1 285 ? -53.305 -25.121 -23.800  1.00 43.47  ? 285 THR A C     1 
ATOM   2193  O  O     . THR A 1 285 ? -54.056 -26.067 -24.042  1.00 43.64  ? 285 THR A O     1 
ATOM   2194  C  CB    . THR A 1 285 ? -54.818 -24.058 -22.082  1.00 37.21  ? 285 THR A CB    1 
ATOM   2195  O  OG1   . THR A 1 285 ? -55.354 -23.142 -23.023  1.00 35.36  ? 285 THR A OG1   1 
ATOM   2196  C  CG2   . THR A 1 285 ? -54.969 -23.444 -20.707  1.00 42.74  ? 285 THR A CG2   1 
ATOM   2197  N  N     . ARG A 1 286 ? -52.451 -24.613 -24.706  1.00 43.35  ? 286 ARG A N     1 
ATOM   2198  C  CA    . ARG A 1 286 ? -52.389 -25.046 -26.097  1.00 36.83  ? 286 ARG A CA    1 
ATOM   2199  C  C     . ARG A 1 286 ? -50.961 -24.945 -26.620  1.00 36.67  ? 286 ARG A C     1 
ATOM   2200  O  O     . ARG A 1 286 ? -50.121 -24.299 -26.016  1.00 42.81  ? 286 ARG A O     1 
ATOM   2201  C  CB    . ARG A 1 286 ? -53.256 -24.172 -27.012  1.00 36.60  ? 286 ARG A CB    1 
ATOM   2202  C  CG    . ARG A 1 286 ? -54.745 -24.144 -26.702  1.00 36.39  ? 286 ARG A CG    1 
ATOM   2203  C  CD    . ARG A 1 286 ? -55.451 -25.468 -26.997  1.00 40.29  ? 286 ARG A CD    1 
ATOM   2204  N  NE    . ARG A 1 286 ? -56.908 -25.362 -26.901  1.00 38.88  ? 286 ARG A NE    1 
ATOM   2205  C  CZ    . ARG A 1 286 ? -57.601 -25.427 -25.771  1.00 39.39  ? 286 ARG A CZ    1 
ATOM   2206  N  NH1   . ARG A 1 286 ? -56.990 -25.607 -24.618  1.00 38.99  ? 286 ARG A NH1   1 
ATOM   2207  N  NH2   . ARG A 1 286 ? -58.911 -25.281 -25.791  1.00 46.44  ? 286 ARG A NH2   1 
ATOM   2208  N  N     . THR A 1 287 ? -50.691 -25.619 -27.744  1.00 41.68  ? 287 THR A N     1 
ATOM   2209  C  CA    . THR A 1 287 ? -49.401 -25.576 -28.414  1.00 41.09  ? 287 THR A CA    1 
ATOM   2210  C  C     . THR A 1 287 ? -49.650 -25.128 -29.847  1.00 40.16  ? 287 THR A C     1 
ATOM   2211  O  O     . THR A 1 287 ? -50.804 -25.142 -30.300  1.00 38.55  ? 287 THR A O     1 
ATOM   2212  C  CB    . THR A 1 287 ? -48.687 -26.935 -28.403  1.00 43.21  ? 287 THR A CB    1 
ATOM   2213  O  OG1   . THR A 1 287 ? -49.370 -27.810 -29.307  1.00 45.01  ? 287 THR A OG1   1 
ATOM   2214  C  CG2   . THR A 1 287 ? -48.612 -27.551 -27.022  1.00 44.72  ? 287 THR A CG2   1 
ATOM   2215  N  N     . LYS A 1 288 ? -48.561 -24.819 -30.572  1.00 37.23  ? 288 LYS A N     1 
ATOM   2216  C  CA    . LYS A 1 288 ? -48.692 -24.201 -31.883  1.00 39.80  ? 288 LYS A CA    1 
ATOM   2217  C  C     . LYS A 1 288 ? -49.285 -25.185 -32.892  1.00 38.72  ? 288 LYS A C     1 
ATOM   2218  O  O     . LYS A 1 288 ? -50.114 -24.810 -33.705  1.00 38.16  ? 288 LYS A O     1 
ATOM   2219  C  CB    . LYS A 1 288 ? -47.352 -23.694 -32.410  1.00 41.80  ? 288 LYS A CB    1 
ATOM   2220  C  CG    . LYS A 1 288 ? -47.502 -22.906 -33.700  1.00 44.16  ? 288 LYS A CG    1 
ATOM   2221  C  CD    . LYS A 1 288 ? -46.248 -22.207 -34.161  1.00 50.61  ? 288 LYS A CD    1 
ATOM   2222  C  CE    . LYS A 1 288 ? -45.296 -23.111 -34.897  1.00 50.98  ? 288 LYS A CE    1 
ATOM   2223  N  NZ    . LYS A 1 288 ? -44.516 -22.356 -35.908  1.00 54.42  ? 288 LYS A NZ    1 
ATOM   2224  N  N     . SER A 1 289 ? -48.825 -26.432 -32.838  1.00 39.50  ? 289 SER A N     1 
ATOM   2225  C  CA    . SER A 1 289 ? -49.210 -27.450 -33.797  1.00 42.82  ? 289 SER A CA    1 
ATOM   2226  C  C     . SER A 1 289 ? -50.698 -27.779 -33.696  1.00 40.08  ? 289 SER A C     1 
ATOM   2227  O  O     . SER A 1 289 ? -51.267 -28.367 -34.602  1.00 40.90  ? 289 SER A O     1 
ATOM   2228  C  CB    . SER A 1 289 ? -48.354 -28.658 -33.606  1.00 39.09  ? 289 SER A CB    1 
ATOM   2229  O  OG    . SER A 1 289 ? -48.488 -29.109 -32.270  1.00 41.17  ? 289 SER A OG    1 
ATOM   2230  N  N     . GLN A 1 290 ? -51.379 -27.328 -32.646  1.00 38.75  ? 290 GLN A N     1 
ATOM   2231  C  CA    . GLN A 1 290 ? -52.809 -27.557 -32.561  1.00 38.03  ? 290 GLN A CA    1 
ATOM   2232  C  C     . GLN A 1 290 ? -53.597 -26.506 -33.341  1.00 41.43  ? 290 GLN A C     1 
ATOM   2233  O  O     . GLN A 1 290 ? -54.810 -26.634 -33.469  1.00 43.87  ? 290 GLN A O     1 
ATOM   2234  C  CB    . GLN A 1 290 ? -53.237 -27.592 -31.098  1.00 38.56  ? 290 GLN A CB    1 
ATOM   2235  C  CG    . GLN A 1 290 ? -52.506 -28.648 -30.277  1.00 41.52  ? 290 GLN A CG    1 
ATOM   2236  C  CD    . GLN A 1 290 ? -52.968 -28.557 -28.845  1.00 45.49  ? 290 GLN A CD    1 
ATOM   2237  O  OE1   . GLN A 1 290 ? -52.792 -27.545 -28.176  1.00 45.31  ? 290 GLN A OE1   1 
ATOM   2238  N  NE2   . GLN A 1 290 ? -53.683 -29.572 -28.400  1.00 53.25  ? 290 GLN A NE2   1 
ATOM   2239  N  N     . TYR A 1 291 ? -52.936 -25.467 -33.864  1.00 41.05  ? 291 TYR A N     1 
ATOM   2240  C  CA    . TYR A 1 291 ? -53.640 -24.438 -34.615  1.00 40.42  ? 291 TYR A CA    1 
ATOM   2241  C  C     . TYR A 1 291 ? -52.971 -24.121 -35.955  1.00 41.52  ? 291 TYR A C     1 
ATOM   2242  O  O     . TYR A 1 291 ? -53.594 -23.547 -36.848  1.00 42.22  ? 291 TYR A O     1 
ATOM   2243  C  CB    . TYR A 1 291 ? -53.751 -23.182 -33.754  1.00 44.48  ? 291 TYR A CB    1 
ATOM   2244  C  CG    . TYR A 1 291 ? -54.768 -23.282 -32.650  1.00 43.08  ? 291 TYR A CG    1 
ATOM   2245  C  CD1   . TYR A 1 291 ? -56.116 -23.133 -32.917  1.00 42.58  ? 291 TYR A CD1   1 
ATOM   2246  C  CD2   . TYR A 1 291 ? -54.383 -23.551 -31.343  1.00 47.40  ? 291 TYR A CD2   1 
ATOM   2247  C  CE1   . TYR A 1 291 ? -57.061 -23.214 -31.905  1.00 49.44  ? 291 TYR A CE1   1 
ATOM   2248  C  CE2   . TYR A 1 291 ? -55.317 -23.663 -30.326  1.00 48.80  ? 291 TYR A CE2   1 
ATOM   2249  C  CZ    . TYR A 1 291 ? -56.661 -23.490 -30.608  1.00 44.38  ? 291 TYR A CZ    1 
ATOM   2250  O  OH    . TYR A 1 291 ? -57.603 -23.605 -29.632  1.00 49.29  ? 291 TYR A OH    1 
ATOM   2251  N  N     . TYR A 1 292 ? -51.704 -24.487 -36.121  1.00 42.47  ? 292 TYR A N     1 
ATOM   2252  C  CA    . TYR A 1 292 ? -50.977 -24.058 -37.303  1.00 44.89  ? 292 TYR A CA    1 
ATOM   2253  C  C     . TYR A 1 292 ? -49.833 -25.025 -37.552  1.00 46.11  ? 292 TYR A C     1 
ATOM   2254  O  O     . TYR A 1 292 ? -49.087 -25.307 -36.628  1.00 50.16  ? 292 TYR A O     1 
ATOM   2255  C  CB    . TYR A 1 292 ? -50.433 -22.640 -37.117  1.00 48.63  ? 292 TYR A CB    1 
ATOM   2256  C  CG    . TYR A 1 292 ? -49.710 -22.091 -38.320  1.00 46.68  ? 292 TYR A CG    1 
ATOM   2257  C  CD1   . TYR A 1 292 ? -50.370 -21.934 -39.525  1.00 50.06  ? 292 TYR A CD1   1 
ATOM   2258  C  CD2   . TYR A 1 292 ? -48.369 -21.732 -38.261  1.00 54.89  ? 292 TYR A CD2   1 
ATOM   2259  C  CE1   . TYR A 1 292 ? -49.730 -21.417 -40.638  1.00 48.17  ? 292 TYR A CE1   1 
ATOM   2260  C  CE2   . TYR A 1 292 ? -47.708 -21.206 -39.362  1.00 49.69  ? 292 TYR A CE2   1 
ATOM   2261  C  CZ    . TYR A 1 292 ? -48.394 -21.053 -40.555  1.00 52.35  ? 292 TYR A CZ    1 
ATOM   2262  O  OH    . TYR A 1 292 ? -47.754 -20.556 -41.666  1.00 50.64  ? 292 TYR A OH    1 
ATOM   2263  N  N     . ASP A 1 293 ? -49.721 -25.522 -38.791  1.00 51.30  ? 293 ASP A N     1 
ATOM   2264  C  CA    . ASP A 1 293 ? -48.719 -26.513 -39.167  1.00 60.60  ? 293 ASP A CA    1 
ATOM   2265  C  C     . ASP A 1 293 ? -47.467 -25.885 -39.797  1.00 53.38  ? 293 ASP A C     1 
ATOM   2266  O  O     . ASP A 1 293 ? -46.481 -26.578 -40.026  1.00 58.24  ? 293 ASP A O     1 
ATOM   2267  C  CB    . ASP A 1 293 ? -49.324 -27.555 -40.118  1.00 69.37  ? 293 ASP A CB    1 
ATOM   2268  C  CG    . ASP A 1 293 ? -50.188 -28.606 -39.435  1.00 82.62  ? 293 ASP A CG    1 
ATOM   2269  O  OD1   . ASP A 1 293 ? -50.046 -28.806 -38.188  1.00 81.74  ? 293 ASP A OD1   1 
ATOM   2270  O  OD2   . ASP A 1 293 ? -51.019 -29.215 -40.147  1.00 100.53 ? 293 ASP A OD2   1 
ATOM   2271  N  N     . GLY A 1 294 ? -47.470 -24.582 -40.083  1.00 54.30  ? 294 GLY A N     1 
ATOM   2272  C  CA    . GLY A 1 294 ? -46.288 -23.955 -40.661  1.00 51.15  ? 294 GLY A CA    1 
ATOM   2273  C  C     . GLY A 1 294 ? -45.127 -23.836 -39.675  1.00 49.88  ? 294 GLY A C     1 
ATOM   2274  O  O     . GLY A 1 294 ? -45.313 -23.884 -38.461  1.00 51.08  ? 294 GLY A O     1 
ATOM   2275  N  N     . ASP A 1 295 ? -43.921 -23.665 -40.227  1.00 52.51  ? 295 ASP A N     1 
ATOM   2276  C  CA    . ASP A 1 295 ? -42.702 -23.496 -39.453  1.00 54.26  ? 295 ASP A CA    1 
ATOM   2277  C  C     . ASP A 1 295 ? -42.612 -22.075 -38.895  1.00 55.61  ? 295 ASP A C     1 
ATOM   2278  O  O     . ASP A 1 295 ? -41.997 -21.858 -37.850  1.00 56.58  ? 295 ASP A O     1 
ATOM   2279  C  CB    . ASP A 1 295 ? -41.463 -23.818 -40.295  1.00 65.01  ? 295 ASP A CB    1 
ATOM   2280  C  CG    . ASP A 1 295 ? -41.370 -25.275 -40.731  1.00 72.35  ? 295 ASP A CG    1 
ATOM   2281  O  OD1   . ASP A 1 295 ? -41.775 -26.157 -39.936  1.00 71.31  ? 295 ASP A OD1   1 
ATOM   2282  O  OD2   . ASP A 1 295 ? -40.853 -25.525 -41.841  1.00 69.20  ? 295 ASP A OD2   1 
ATOM   2283  N  N     . GLY A 1 296 ? -43.233 -21.104 -39.574  1.00 53.04  ? 296 GLY A N     1 
ATOM   2284  C  CA    . GLY A 1 296 ? -43.120 -19.714 -39.150  1.00 57.30  ? 296 GLY A CA    1 
ATOM   2285  C  C     . GLY A 1 296 ? -44.107 -19.333 -38.046  1.00 54.12  ? 296 GLY A C     1 
ATOM   2286  O  O     . GLY A 1 296 ? -44.917 -20.148 -37.611  1.00 48.79  ? 296 GLY A O     1 
ATOM   2287  N  N     . PRO A 1 297 ? -44.110 -18.059 -37.596  1.00 48.65  ? 297 PRO A N     1 
ATOM   2288  C  CA    . PRO A 1 297 ? -45.079 -17.603 -36.596  1.00 44.16  ? 297 PRO A CA    1 
ATOM   2289  C  C     . PRO A 1 297 ? -46.511 -17.695 -37.120  1.00 41.58  ? 297 PRO A C     1 
ATOM   2290  O  O     . PRO A 1 297 ? -46.730 -17.706 -38.316  1.00 42.85  ? 297 PRO A O     1 
ATOM   2291  C  CB    . PRO A 1 297 ? -44.658 -16.141 -36.374  1.00 49.31  ? 297 PRO A CB    1 
ATOM   2292  C  CG    . PRO A 1 297 ? -43.937 -15.741 -37.650  1.00 48.78  ? 297 PRO A CG    1 
ATOM   2293  C  CD    . PRO A 1 297 ? -43.193 -16.995 -38.043  1.00 48.69  ? 297 PRO A CD    1 
ATOM   2294  N  N     . ILE A 1 298 ? -47.508 -17.686 -36.236  1.00 42.18  ? 298 ILE A N     1 
ATOM   2295  C  CA    . ILE A 1 298 ? -48.888 -17.897 -36.660  1.00 38.95  ? 298 ILE A CA    1 
ATOM   2296  C  C     . ILE A 1 298 ? -49.381 -16.679 -37.419  1.00 43.52  ? 298 ILE A C     1 
ATOM   2297  O  O     . ILE A 1 298 ? -49.070 -15.546 -37.061  1.00 44.37  ? 298 ILE A O     1 
ATOM   2298  C  CB    . ILE A 1 298 ? -49.821 -18.198 -35.471  1.00 40.54  ? 298 ILE A CB    1 
ATOM   2299  C  CG1   . ILE A 1 298 ? -50.000 -16.961 -34.583  1.00 38.50  ? 298 ILE A CG1   1 
ATOM   2300  C  CG2   . ILE A 1 298 ? -49.325 -19.414 -34.693  1.00 38.93  ? 298 ILE A CG2   1 
ATOM   2301  C  CD1   . ILE A 1 298 ? -51.046 -17.089 -33.507  1.00 38.77  ? 298 ILE A CD1   1 
ATOM   2302  N  N     . PRO A 1 299 ? -50.215 -16.866 -38.460  1.00 42.64  ? 299 PRO A N     1 
ATOM   2303  C  CA    . PRO A 1 299 ? -50.795 -15.735 -39.172  1.00 42.66  ? 299 PRO A CA    1 
ATOM   2304  C  C     . PRO A 1 299 ? -52.041 -15.244 -38.449  1.00 44.25  ? 299 PRO A C     1 
ATOM   2305  O  O     . PRO A 1 299 ? -52.531 -15.901 -37.530  1.00 40.38  ? 299 PRO A O     1 
ATOM   2306  C  CB    . PRO A 1 299 ? -51.082 -16.310 -40.574  1.00 40.62  ? 299 PRO A CB    1 
ATOM   2307  C  CG    . PRO A 1 299 ? -51.398 -17.778 -40.292  1.00 44.45  ? 299 PRO A CG    1 
ATOM   2308  C  CD    . PRO A 1 299 ? -50.540 -18.150 -39.095  1.00 45.70  ? 299 PRO A CD    1 
ATOM   2309  N  N     . PRO A 1 300 ? -52.513 -14.029 -38.797  1.00 40.57  ? 300 PRO A N     1 
ATOM   2310  C  CA    . PRO A 1 300 ? -53.689 -13.432 -38.173  1.00 42.51  ? 300 PRO A CA    1 
ATOM   2311  C  C     . PRO A 1 300 ? -54.950 -14.292 -38.160  1.00 51.18  ? 300 PRO A C     1 
ATOM   2312  O  O     . PRO A 1 300 ? -55.712 -14.264 -37.189  1.00 47.86  ? 300 PRO A O     1 
ATOM   2313  C  CB    . PRO A 1 300 ? -53.931 -12.199 -39.062  1.00 44.55  ? 300 PRO A CB    1 
ATOM   2314  C  CG    . PRO A 1 300 ? -52.529 -11.791 -39.464  1.00 45.23  ? 300 PRO A CG    1 
ATOM   2315  C  CD    . PRO A 1 300 ? -51.841 -13.112 -39.738  1.00 42.30  ? 300 PRO A CD    1 
ATOM   2316  N  N     . SER A 1 301 ? -55.197 -15.010 -39.265  1.00 48.32  ? 301 SER A N     1 
ATOM   2317  C  CA    . SER A 1 301 ? -56.385 -15.848 -39.349  1.00 47.42  ? 301 SER A CA    1 
ATOM   2318  C  C     . SER A 1 301 ? -56.353 -16.890 -38.226  1.00 40.93  ? 301 SER A C     1 
ATOM   2319  O  O     . SER A 1 301 ? -57.392 -17.163 -37.622  1.00 43.43  ? 301 SER A O     1 
ATOM   2320  C  CB    . SER A 1 301 ? -56.519 -16.493 -40.699  1.00 40.33  ? 301 SER A CB    1 
ATOM   2321  O  OG    . SER A 1 301 ? -55.448 -17.398 -40.878  1.00 46.77  ? 301 SER A OG    1 
ATOM   2322  N  N     . VAL A 1 302 ? -55.159 -17.427 -37.918  1.00 40.71  ? 302 VAL A N     1 
ATOM   2323  C  CA    . VAL A 1 302 ? -54.985 -18.412 -36.861  1.00 43.59  ? 302 VAL A CA    1 
ATOM   2324  C  C     . VAL A 1 302 ? -55.108 -17.755 -35.479  1.00 47.45  ? 302 VAL A C     1 
ATOM   2325  O  O     . VAL A 1 302 ? -55.744 -18.320 -34.584  1.00 42.57  ? 302 VAL A O     1 
ATOM   2326  C  CB    . VAL A 1 302 ? -53.675 -19.207 -37.007  1.00 45.79  ? 302 VAL A CB    1 
ATOM   2327  C  CG1   . VAL A 1 302 ? -53.366 -20.036 -35.769  1.00 47.06  ? 302 VAL A CG1   1 
ATOM   2328  C  CG2   . VAL A 1 302 ? -53.723 -20.109 -38.229  1.00 48.63  ? 302 VAL A CG2   1 
ATOM   2329  N  N     . ALA A 1 303 ? -54.553 -16.549 -35.315  1.00 45.64  ? 303 ALA A N     1 
ATOM   2330  C  CA    . ALA A 1 303 ? -54.779 -15.766 -34.105  1.00 45.27  ? 303 ALA A CA    1 
ATOM   2331  C  C     . ALA A 1 303 ? -56.273 -15.658 -33.782  1.00 38.81  ? 303 ALA A C     1 
ATOM   2332  O  O     . ALA A 1 303 ? -56.673 -15.882 -32.641  1.00 40.54  ? 303 ALA A O     1 
ATOM   2333  C  CB    . ALA A 1 303 ? -54.146 -14.398 -34.240  1.00 47.48  ? 303 ALA A CB    1 
ATOM   2334  N  N     . LYS A 1 304 ? -57.092 -15.311 -34.781  1.00 38.52  ? 304 LYS A N     1 
ATOM   2335  C  CA    . LYS A 1 304 ? -58.533 -15.119 -34.598  1.00 43.01  ? 304 LYS A CA    1 
ATOM   2336  C  C     . LYS A 1 304 ? -59.182 -16.421 -34.139  1.00 44.89  ? 304 LYS A C     1 
ATOM   2337  O  O     . LYS A 1 304 ? -60.007 -16.407 -33.223  1.00 43.18  ? 304 LYS A O     1 
ATOM   2338  C  CB    . LYS A 1 304 ? -59.178 -14.596 -35.884  1.00 45.95  ? 304 LYS A CB    1 
ATOM   2339  C  CG    . LYS A 1 304 ? -58.987 -13.093 -36.108  1.00 58.70  ? 304 LYS A CG    1 
ATOM   2340  C  CD    . LYS A 1 304 ? -58.798 -12.669 -37.553  1.00 66.90  ? 304 LYS A CD    1 
ATOM   2341  C  CE    . LYS A 1 304 ? -60.083 -12.439 -38.313  1.00 80.79  ? 304 LYS A CE    1 
ATOM   2342  N  NZ    . LYS A 1 304 ? -60.727 -11.170 -37.906  1.00 94.02  ? 304 LYS A NZ    1 
ATOM   2343  N  N     . THR A 1 305 ? -58.741 -17.547 -34.713  1.00 40.46  ? 305 THR A N     1 
ATOM   2344  C  CA    . THR A 1 305 ? -59.320 -18.841 -34.377  1.00 43.72  ? 305 THR A CA    1 
ATOM   2345  C  C     . THR A 1 305 ? -59.049 -19.152 -32.912  1.00 39.13  ? 305 THR A C     1 
ATOM   2346  O  O     . THR A 1 305 ? -59.924 -19.650 -32.205  1.00 38.90  ? 305 THR A O     1 
ATOM   2347  C  CB    . THR A 1 305 ? -58.803 -19.937 -35.320  1.00 44.09  ? 305 THR A CB    1 
ATOM   2348  O  OG1   . THR A 1 305 ? -59.489 -19.695 -36.544  1.00 47.16  ? 305 THR A OG1   1 
ATOM   2349  C  CG2   . THR A 1 305 ? -59.087 -21.350 -34.856  1.00 45.16  ? 305 THR A CG2   1 
ATOM   2350  N  N     . MET A 1 306 ? -57.834 -18.813 -32.478  1.00 40.81  ? 306 MET A N     1 
ATOM   2351  C  CA    . MET A 1 306 ? -57.381 -19.098 -31.139  1.00 42.51  ? 306 MET A CA    1 
ATOM   2352  C  C     . MET A 1 306 ? -58.171 -18.273 -30.126  1.00 42.46  ? 306 MET A C     1 
ATOM   2353  O  O     . MET A 1 306 ? -58.579 -18.778 -29.084  1.00 39.63  ? 306 MET A O     1 
ATOM   2354  C  CB    . MET A 1 306 ? -55.891 -18.789 -31.029  1.00 45.70  ? 306 MET A CB    1 
ATOM   2355  C  CG    . MET A 1 306 ? -55.028 -19.885 -31.571  1.00 48.54  ? 306 MET A CG    1 
ATOM   2356  S  SD    . MET A 1 306 ? -53.293 -19.393 -31.661  1.00 51.39  ? 306 MET A SD    1 
ATOM   2357  C  CE    . MET A 1 306 ? -52.882 -19.357 -29.923  1.00 57.55  ? 306 MET A CE    1 
ATOM   2358  N  N     . MET A 1 307 ? -58.367 -16.997 -30.447  1.00 39.39  ? 307 MET A N     1 
ATOM   2359  C  CA    . MET A 1 307 ? -59.135 -16.098 -29.613  1.00 40.53  ? 307 MET A CA    1 
ATOM   2360  C  C     . MET A 1 307 ? -60.574 -16.616 -29.436  1.00 46.31  ? 307 MET A C     1 
ATOM   2361  O  O     . MET A 1 307 ? -61.116 -16.595 -28.339  1.00 41.26  ? 307 MET A O     1 
ATOM   2362  C  CB    . MET A 1 307 ? -59.179 -14.728 -30.291  1.00 38.20  ? 307 MET A CB    1 
ATOM   2363  C  CG    . MET A 1 307 ? -57.867 -13.984 -30.215  1.00 42.78  ? 307 MET A CG    1 
ATOM   2364  S  SD    . MET A 1 307 ? -57.831 -12.576 -31.352  1.00 45.60  ? 307 MET A SD    1 
ATOM   2365  C  CE    . MET A 1 307 ? -59.074 -11.502 -30.664  1.00 38.32  ? 307 MET A CE    1 
ATOM   2366  N  N     . ALA A 1 308 ? -61.205 -17.052 -30.532  1.00 43.92  ? 308 ALA A N     1 
ATOM   2367  C  CA    . ALA A 1 308 ? -62.567 -17.576 -30.516  1.00 43.86  ? 308 ALA A CA    1 
ATOM   2368  C  C     . ALA A 1 308 ? -62.646 -18.910 -29.769  1.00 40.96  ? 308 ALA A C     1 
ATOM   2369  O  O     . ALA A 1 308 ? -63.590 -19.114 -29.036  1.00 43.28  ? 308 ALA A O     1 
ATOM   2370  C  CB    . ALA A 1 308 ? -63.090 -17.711 -31.926  1.00 40.64  ? 308 ALA A CB    1 
ATOM   2371  N  N     . ASP A 1 309 ? -61.645 -19.788 -29.899  1.00 40.67  ? 309 ASP A N     1 
ATOM   2372  C  CA    . ASP A 1 309 ? -61.634 -21.025 -29.133  1.00 48.17  ? 309 ASP A CA    1 
ATOM   2373  C  C     . ASP A 1 309 ? -61.508 -20.778 -27.627  1.00 51.47  ? 309 ASP A C     1 
ATOM   2374  O  O     . ASP A 1 309 ? -62.199 -21.419 -26.839  1.00 45.50  ? 309 ASP A O     1 
ATOM   2375  C  CB    . ASP A 1 309 ? -60.470 -21.944 -29.488  1.00 46.78  ? 309 ASP A CB    1 
ATOM   2376  C  CG    . ASP A 1 309 ? -60.691 -22.782 -30.729  1.00 52.95  ? 309 ASP A CG    1 
ATOM   2377  O  OD1   . ASP A 1 309 ? -61.555 -22.394 -31.551  1.00 49.06  ? 309 ASP A OD1   1 
ATOM   2378  O  OD2   . ASP A 1 309 ? -59.988 -23.822 -30.844  1.00 50.67  ? 309 ASP A OD2   1 
ATOM   2379  N  N     . LEU A 1 310 ? -60.583 -19.892 -27.234  1.00 45.59  ? 310 LEU A N     1 
ATOM   2380  C  CA    . LEU A 1 310 ? -60.127 -19.792 -25.855  1.00 42.18  ? 310 LEU A CA    1 
ATOM   2381  C  C     . LEU A 1 310 ? -60.825 -18.672 -25.083  1.00 40.13  ? 310 LEU A C     1 
ATOM   2382  O  O     . LEU A 1 310 ? -60.662 -18.622 -23.868  1.00 43.14  ? 310 LEU A O     1 
ATOM   2383  C  CB    . LEU A 1 310 ? -58.613 -19.559 -25.854  1.00 41.95  ? 310 LEU A CB    1 
ATOM   2384  C  CG    . LEU A 1 310 ? -57.794 -20.708 -26.419  1.00 42.47  ? 310 LEU A CG    1 
ATOM   2385  C  CD1   . LEU A 1 310 ? -56.329 -20.308 -26.561  1.00 37.44  ? 310 LEU A CD1   1 
ATOM   2386  C  CD2   . LEU A 1 310 ? -57.954 -21.959 -25.546  1.00 43.19  ? 310 LEU A CD2   1 
ATOM   2387  N  N     . ASP A 1 311 ? -61.625 -17.832 -25.759  1.00 38.64  ? 311 ASP A N     1 
ATOM   2388  C  CA    . ASP A 1 311 ? -62.150 -16.601 -25.166  1.00 44.13  ? 311 ASP A CA    1 
ATOM   2389  C  C     . ASP A 1 311 ? -61.004 -15.751 -24.604  1.00 43.38  ? 311 ASP A C     1 
ATOM   2390  O  O     . ASP A 1 311 ? -61.064 -15.298 -23.466  1.00 39.66  ? 311 ASP A O     1 
ATOM   2391  C  CB    . ASP A 1 311 ? -63.198 -16.889 -24.083  1.00 47.34  ? 311 ASP A CB    1 
ATOM   2392  C  CG    . ASP A 1 311 ? -64.465 -17.610 -24.543  1.00 47.29  ? 311 ASP A CG    1 
ATOM   2393  O  OD1   . ASP A 1 311 ? -64.669 -17.757 -25.765  1.00 36.71  ? 311 ASP A OD1   1 
ATOM   2394  O  OD2   . ASP A 1 311 ? -65.255 -18.010 -23.659  1.00 51.81  ? 311 ASP A OD2   1 
ATOM   2395  N  N     . LEU A 1 312 ? -59.939 -15.583 -25.410  1.00 42.20  ? 312 LEU A N     1 
ATOM   2396  C  CA    . LEU A 1 312 ? -58.876 -14.631 -25.150  1.00 41.65  ? 312 LEU A CA    1 
ATOM   2397  C  C     . LEU A 1 312 ? -58.920 -13.520 -26.190  1.00 42.49  ? 312 LEU A C     1 
ATOM   2398  O  O     . LEU A 1 312 ? -59.459 -13.714 -27.280  1.00 39.83  ? 312 LEU A O     1 
ATOM   2399  C  CB    . LEU A 1 312 ? -57.542 -15.370 -25.223  1.00 43.78  ? 312 LEU A CB    1 
ATOM   2400  C  CG    . LEU A 1 312 ? -57.351 -16.434 -24.153  1.00 41.34  ? 312 LEU A CG    1 
ATOM   2401  C  CD1   . LEU A 1 312 ? -55.981 -17.068 -24.287  1.00 40.37  ? 312 LEU A CD1   1 
ATOM   2402  C  CD2   . LEU A 1 312 ? -57.542 -15.828 -22.770  1.00 42.58  ? 312 LEU A CD2   1 
ATOM   2403  N  N     . GLY A 1 313 ? -58.311 -12.372 -25.851  1.00 46.67  ? 313 GLY A N     1 
ATOM   2404  C  CA    . GLY A 1 313 ? -58.062 -11.316 -26.821  1.00 41.17  ? 313 GLY A CA    1 
ATOM   2405  C  C     . GLY A 1 313 ? -56.633 -11.376 -27.347  1.00 37.76  ? 313 GLY A C     1 
ATOM   2406  O  O     . GLY A 1 313 ? -55.861 -12.265 -26.982  1.00 39.06  ? 313 GLY A O     1 
ATOM   2407  N  N     . MET A 1 314 ? -56.269 -10.378 -28.166  1.00 38.41  ? 314 MET A N     1 
ATOM   2408  C  CA    . MET A 1 314 ? -54.884 -10.134 -28.556  1.00 35.86  ? 314 MET A CA    1 
ATOM   2409  C  C     . MET A 1 314 ? -54.085 -9.667  -27.343  1.00 37.23  ? 314 MET A C     1 
ATOM   2410  O  O     . MET A 1 314 ? -52.884 -9.904  -27.274  1.00 39.68  ? 314 MET A O     1 
ATOM   2411  C  CB    . MET A 1 314 ? -54.828 -9.088  -29.672  1.00 40.66  ? 314 MET A CB    1 
ATOM   2412  C  CG    . MET A 1 314 ? -55.272 -9.660  -31.006  1.00 44.04  ? 314 MET A CG    1 
ATOM   2413  S  SD    . MET A 1 314 ? -54.139 -10.961 -31.539  1.00 47.98  ? 314 MET A SD    1 
ATOM   2414  C  CE    . MET A 1 314 ? -52.690 -9.978  -31.927  1.00 56.61  ? 314 MET A CE    1 
ATOM   2415  N  N     . TRP A 1 315 ? -54.798 -9.075  -26.372  1.00 38.32  ? 315 TRP A N     1 
ATOM   2416  C  CA    . TRP A 1 315 ? -54.257 -8.654  -25.091  1.00 40.52  ? 315 TRP A CA    1 
ATOM   2417  C  C     . TRP A 1 315 ? -55.190 -9.105  -23.960  1.00 41.77  ? 315 TRP A C     1 
ATOM   2418  O  O     . TRP A 1 315 ? -56.391 -8.897  -24.038  1.00 35.55  ? 315 TRP A O     1 
ATOM   2419  C  CB    . TRP A 1 315 ? -54.086 -7.121  -25.098  1.00 39.47  ? 315 TRP A CB    1 
ATOM   2420  C  CG    . TRP A 1 315 ? -53.065 -6.642  -26.079  1.00 36.27  ? 315 TRP A CG    1 
ATOM   2421  C  CD1   . TRP A 1 315 ? -53.286 -5.974  -27.240  1.00 37.93  ? 315 TRP A CD1   1 
ATOM   2422  C  CD2   . TRP A 1 315 ? -51.647 -6.830  -25.990  1.00 32.67  ? 315 TRP A CD2   1 
ATOM   2423  N  NE1   . TRP A 1 315 ? -52.106 -5.721  -27.875  1.00 39.50  ? 315 TRP A NE1   1 
ATOM   2424  C  CE2   . TRP A 1 315 ? -51.081 -6.243  -27.132  1.00 40.08  ? 315 TRP A CE2   1 
ATOM   2425  C  CE3   . TRP A 1 315 ? -50.815 -7.455  -25.072  1.00 34.36  ? 315 TRP A CE3   1 
ATOM   2426  C  CZ2   . TRP A 1 315 ? -49.710 -6.252  -27.368  1.00 39.69  ? 315 TRP A CZ2   1 
ATOM   2427  C  CZ3   . TRP A 1 315 ? -49.462 -7.478  -25.309  1.00 37.09  ? 315 TRP A CZ3   1 
ATOM   2428  C  CH2   . TRP A 1 315 ? -48.918 -6.849  -26.421  1.00 34.82  ? 315 TRP A CH2   1 
ATOM   2429  N  N     . ASN A 1 316 ? -54.610 -9.663  -22.888  1.00 41.52  ? 316 ASN A N     1 
ATOM   2430  C  CA    . ASN A 1 316 ? -55.362 -10.245 -21.789  1.00 39.54  ? 316 ASN A CA    1 
ATOM   2431  C  C     . ASN A 1 316 ? -54.861 -9.679  -20.463  1.00 37.81  ? 316 ASN A C     1 
ATOM   2432  O  O     . ASN A 1 316 ? -53.755 -9.991  -20.031  1.00 36.86  ? 316 ASN A O     1 
ATOM   2433  C  CB    . ASN A 1 316 ? -55.256 -11.775 -21.870  1.00 40.55  ? 316 ASN A CB    1 
ATOM   2434  C  CG    . ASN A 1 316 ? -55.709 -12.250 -23.237  1.00 41.43  ? 316 ASN A CG    1 
ATOM   2435  O  OD1   . ASN A 1 316 ? -56.901 -12.341 -23.491  1.00 44.12  ? 316 ASN A OD1   1 
ATOM   2436  N  ND2   . ASN A 1 316 ? -54.781 -12.402 -24.167  1.00 43.83  ? 316 ASN A ND2   1 
ATOM   2437  N  N     . PHE A 1 317 ? -55.680 -8.834  -19.829  1.00 39.54  ? 317 PHE A N     1 
ATOM   2438  C  CA    . PHE A 1 317 ? -55.307 -8.188  -18.569  1.00 40.60  ? 317 PHE A CA    1 
ATOM   2439  C  C     . PHE A 1 317 ? -55.837 -9.030  -17.414  1.00 38.19  ? 317 PHE A C     1 
ATOM   2440  O  O     . PHE A 1 317 ? -57.046 -9.097  -17.188  1.00 34.01  ? 317 PHE A O     1 
ATOM   2441  C  CB    . PHE A 1 317 ? -55.784 -6.719  -18.504  1.00 36.63  ? 317 PHE A CB    1 
ATOM   2442  C  CG    . PHE A 1 317 ? -55.827 -6.069  -17.139  1.00 36.34  ? 317 PHE A CG    1 
ATOM   2443  C  CD1   . PHE A 1 317 ? -54.836 -6.299  -16.196  1.00 40.48  ? 317 PHE A CD1   1 
ATOM   2444  C  CD2   . PHE A 1 317 ? -56.815 -5.146  -16.821  1.00 40.48  ? 317 PHE A CD2   1 
ATOM   2445  C  CE1   . PHE A 1 317 ? -54.894 -5.714  -14.938  1.00 41.48  ? 317 PHE A CE1   1 
ATOM   2446  C  CE2   . PHE A 1 317 ? -56.871 -4.551  -15.565  1.00 39.02  ? 317 PHE A CE2   1 
ATOM   2447  C  CZ    . PHE A 1 317 ? -55.921 -4.847  -14.619  1.00 38.29  ? 317 PHE A CZ    1 
ATOM   2448  N  N     . CYS A 1 318 ? -54.910 -9.654  -16.680  1.00 38.28  ? 318 CYS A N     1 
ATOM   2449  C  CA    . CYS A 1 318 ? -55.256 -10.301 -15.432  1.00 43.40  ? 318 CYS A CA    1 
ATOM   2450  C  C     . CYS A 1 318 ? -54.936 -9.396  -14.248  1.00 40.02  ? 318 CYS A C     1 
ATOM   2451  O  O     . CYS A 1 318 ? -53.868 -8.811  -14.147  1.00 40.90  ? 318 CYS A O     1 
ATOM   2452  C  CB    . CYS A 1 318 ? -54.535 -11.625 -15.282  1.00 47.12  ? 318 CYS A CB    1 
ATOM   2453  S  SG    . CYS A 1 318 ? -55.354 -12.893 -16.262  1.00 52.23  ? 318 CYS A SG    1 
ATOM   2454  N  N     . GLY A 1 319 ? -55.878 -9.324  -13.326  1.00 42.46  ? 319 GLY A N     1 
ATOM   2455  C  CA    . GLY A 1 319 ? -55.696 -8.563  -12.104  1.00 43.87  ? 319 GLY A CA    1 
ATOM   2456  C  C     . GLY A 1 319 ? -56.543 -9.185  -11.019  1.00 41.37  ? 319 GLY A C     1 
ATOM   2457  O  O     . GLY A 1 319 ? -57.247 -10.158 -11.313  1.00 41.57  ? 319 GLY A O     1 
ATOM   2458  N  N     . ALA A 1 320 ? -56.446 -8.657  -9.791   1.00 37.63  ? 320 ALA A N     1 
ATOM   2459  C  CA    . ALA A 1 320 ? -57.293 -9.173  -8.737   1.00 41.43  ? 320 ALA A CA    1 
ATOM   2460  C  C     . ALA A 1 320 ? -57.671 -8.052  -7.787   1.00 41.05  ? 320 ALA A C     1 
ATOM   2461  O  O     . ALA A 1 320 ? -56.876 -7.142  -7.573   1.00 37.76  ? 320 ALA A O     1 
ATOM   2462  C  CB    . ALA A 1 320 ? -56.630 -10.318 -8.005   1.00 39.68  ? 320 ALA A CB    1 
ATOM   2463  N  N     . LEU A 1 321 ? -58.888 -8.214  -7.241   1.00 39.34  ? 321 LEU A N     1 
ATOM   2464  C  CA    . LEU A 1 321 ? -59.442 -7.412  -6.173   1.00 40.53  ? 321 LEU A CA    1 
ATOM   2465  C  C     . LEU A 1 321 ? -59.230 -8.150  -4.858   1.00 39.16  ? 321 LEU A C     1 
ATOM   2466  O  O     . LEU A 1 321 ? -59.319 -9.376  -4.789   1.00 38.84  ? 321 LEU A O     1 
ATOM   2467  C  CB    . LEU A 1 321 ? -60.934 -7.227  -6.433   1.00 44.83  ? 321 LEU A CB    1 
ATOM   2468  C  CG    . LEU A 1 321 ? -61.310 -6.651  -7.794   1.00 44.36  ? 321 LEU A CG    1 
ATOM   2469  C  CD1   . LEU A 1 321 ? -62.803 -6.781  -8.017   1.00 43.39  ? 321 LEU A CD1   1 
ATOM   2470  C  CD2   . LEU A 1 321 ? -60.891 -5.194  -7.902   1.00 45.45  ? 321 LEU A CD2   1 
ATOM   2471  N  N     . TYR A 1 322 ? -58.917 -7.383  -3.813   1.00 37.85  ? 322 TYR A N     1 
ATOM   2472  C  CA    . TYR A 1 322 ? -58.591 -7.936  -2.513   1.00 37.50  ? 322 TYR A CA    1 
ATOM   2473  C  C     . TYR A 1 322 ? -59.276 -7.097  -1.443   1.00 44.01  ? 322 TYR A C     1 
ATOM   2474  O  O     . TYR A 1 322 ? -59.172 -5.876  -1.462   1.00 43.95  ? 322 TYR A O     1 
ATOM   2475  C  CB    . TYR A 1 322 ? -57.086 -7.907  -2.236   1.00 36.09  ? 322 TYR A CB    1 
ATOM   2476  C  CG    . TYR A 1 322 ? -56.206 -8.606  -3.241   1.00 36.22  ? 322 TYR A CG    1 
ATOM   2477  C  CD1   . TYR A 1 322 ? -55.754 -7.942  -4.355   1.00 35.65  ? 322 TYR A CD1   1 
ATOM   2478  C  CD2   . TYR A 1 322 ? -55.790 -9.915  -3.056   1.00 37.06  ? 322 TYR A CD2   1 
ATOM   2479  C  CE1   . TYR A 1 322 ? -54.910 -8.541  -5.271   1.00 34.74  ? 322 TYR A CE1   1 
ATOM   2480  C  CE2   . TYR A 1 322 ? -54.947 -10.540 -3.963   1.00 36.26  ? 322 TYR A CE2   1 
ATOM   2481  C  CZ    . TYR A 1 322 ? -54.513 -9.850  -5.075   1.00 37.31  ? 322 TYR A CZ    1 
ATOM   2482  O  OH    . TYR A 1 322 ? -53.664 -10.410 -5.971   1.00 36.53  ? 322 TYR A OH    1 
ATOM   2483  N  N     . GLY A 1 323 ? -59.982 -7.755  -0.524   1.00 44.32  ? 323 GLY A N     1 
ATOM   2484  C  CA    . GLY A 1 323 ? -60.519 -7.071  0.637    1.00 42.53  ? 323 GLY A CA    1 
ATOM   2485  C  C     . GLY A 1 323 ? -61.990 -7.374  0.848    1.00 43.76  ? 323 GLY A C     1 
ATOM   2486  O  O     . GLY A 1 323 ? -62.545 -8.265  0.199    1.00 43.27  ? 323 GLY A O     1 
ATOM   2487  N  N     . PRO A 1 324 ? -62.656 -6.633  1.767    1.00 50.26  ? 324 PRO A N     1 
ATOM   2488  C  CA    . PRO A 1 324 ? -64.090 -6.801  1.996    1.00 47.55  ? 324 PRO A CA    1 
ATOM   2489  C  C     . PRO A 1 324 ? -64.836 -6.550  0.685    1.00 43.57  ? 324 PRO A C     1 
ATOM   2490  O  O     . PRO A 1 324 ? -64.379 -5.801  -0.171   1.00 49.39  ? 324 PRO A O     1 
ATOM   2491  C  CB    . PRO A 1 324 ? -64.454 -5.774  3.084    1.00 45.77  ? 324 PRO A CB    1 
ATOM   2492  C  CG    . PRO A 1 324 ? -63.153 -5.181  3.583    1.00 48.47  ? 324 PRO A CG    1 
ATOM   2493  C  CD    . PRO A 1 324 ? -62.071 -5.561  2.588    1.00 47.99  ? 324 PRO A CD    1 
ATOM   2494  N  N     . PRO A 1 325 ? -65.987 -7.208  0.454    1.00 48.28  ? 325 PRO A N     1 
ATOM   2495  C  CA    . PRO A 1 325 ? -66.790 -6.953  -0.740   1.00 49.72  ? 325 PRO A CA    1 
ATOM   2496  C  C     . PRO A 1 325 ? -67.078 -5.480  -1.066   1.00 46.19  ? 325 PRO A C     1 
ATOM   2497  O  O     . PRO A 1 325 ? -66.959 -5.079  -2.222   1.00 43.66  ? 325 PRO A O     1 
ATOM   2498  C  CB    . PRO A 1 325 ? -68.069 -7.752  -0.433   1.00 50.75  ? 325 PRO A CB    1 
ATOM   2499  C  CG    . PRO A 1 325 ? -67.551 -8.936  0.352    1.00 50.73  ? 325 PRO A CG    1 
ATOM   2500  C  CD    . PRO A 1 325 ? -66.525 -8.309  1.272    1.00 52.95  ? 325 PRO A CD    1 
ATOM   2501  N  N     . PRO A 1 326 ? -67.506 -4.607  -0.125   1.00 42.72  ? 326 PRO A N     1 
ATOM   2502  C  CA    . PRO A 1 326 ? -67.722 -3.199  -0.481   1.00 45.04  ? 326 PRO A CA    1 
ATOM   2503  C  C     . PRO A 1 326 ? -66.499 -2.544  -1.129   1.00 42.11  ? 326 PRO A C     1 
ATOM   2504  O  O     . PRO A 1 326 ? -66.653 -1.797  -2.091   1.00 44.50  ? 326 PRO A O     1 
ATOM   2505  C  CB    . PRO A 1 326 ? -68.116 -2.524  0.839    1.00 44.13  ? 326 PRO A CB    1 
ATOM   2506  C  CG    . PRO A 1 326 ? -68.674 -3.671  1.665    1.00 43.34  ? 326 PRO A CG    1 
ATOM   2507  C  CD    . PRO A 1 326 ? -67.882 -4.904  1.267    1.00 44.36  ? 326 PRO A CD    1 
ATOM   2508  N  N     . VAL A 1 327 ? -65.295 -2.842  -0.603   1.00 40.74  ? 327 VAL A N     1 
ATOM   2509  C  CA    . VAL A 1 327 ? -64.042 -2.311  -1.139   1.00 41.42  ? 327 VAL A CA    1 
ATOM   2510  C  C     . VAL A 1 327 ? -63.837 -2.847  -2.561   1.00 42.08  ? 327 VAL A C     1 
ATOM   2511  O  O     . VAL A 1 327 ? -63.586 -2.087  -3.487   1.00 41.57  ? 327 VAL A O     1 
ATOM   2512  C  CB    . VAL A 1 327 ? -62.863 -2.654  -0.190   1.00 41.73  ? 327 VAL A CB    1 
ATOM   2513  C  CG1   . VAL A 1 327 ? -61.505 -2.354  -0.782   1.00 41.73  ? 327 VAL A CG1   1 
ATOM   2514  C  CG2   . VAL A 1 327 ? -63.002 -1.962  1.163    1.00 38.64  ? 327 VAL A CG2   1 
ATOM   2515  N  N     . MET A 1 328 ? -64.003 -4.168  -2.729   1.00 40.47  ? 328 MET A N     1 
ATOM   2516  C  CA    . MET A 1 328 ? -63.759 -4.836  -4.000   1.00 39.88  ? 328 MET A CA    1 
ATOM   2517  C  C     . MET A 1 328 ? -64.721 -4.321  -5.068   1.00 41.41  ? 328 MET A C     1 
ATOM   2518  O  O     . MET A 1 328 ? -64.299 -4.038  -6.187   1.00 40.86  ? 328 MET A O     1 
ATOM   2519  C  CB    . MET A 1 328 ? -63.887 -6.363  -3.853   1.00 38.22  ? 328 MET A CB    1 
ATOM   2520  C  CG    . MET A 1 328 ? -62.705 -6.980  -3.133   1.00 40.68  ? 328 MET A CG    1 
ATOM   2521  S  SD    . MET A 1 328 ? -62.550 -8.789  -3.283   1.00 46.63  ? 328 MET A SD    1 
ATOM   2522  C  CE    . MET A 1 328 ? -64.220 -9.304  -2.873   1.00 42.98  ? 328 MET A CE    1 
ATOM   2523  N  N     . ASP A 1 329 ? -66.002 -4.163  -4.702   1.00 42.68  ? 329 ASP A N     1 
ATOM   2524  C  CA    . ASP A 1 329 ? -67.001 -3.637  -5.615   1.00 43.56  ? 329 ASP A CA    1 
ATOM   2525  C  C     . ASP A 1 329 ? -66.653 -2.214  -6.045   1.00 45.10  ? 329 ASP A C     1 
ATOM   2526  O  O     . ASP A 1 329 ? -66.829 -1.845  -7.202   1.00 46.97  ? 329 ASP A O     1 
ATOM   2527  C  CB    . ASP A 1 329 ? -68.377 -3.558  -4.956   1.00 45.85  ? 329 ASP A CB    1 
ATOM   2528  C  CG    . ASP A 1 329 ? -69.037 -4.898  -4.712   1.00 47.86  ? 329 ASP A CG    1 
ATOM   2529  O  OD1   . ASP A 1 329 ? -68.480 -5.924  -5.150   1.00 56.87  ? 329 ASP A OD1   1 
ATOM   2530  O  OD2   . ASP A 1 329 ? -70.102 -4.903  -4.063   1.00 53.43  ? 329 ASP A OD2   1 
ATOM   2531  N  N     . THR A 1 330 ? -66.247 -1.383  -5.088   1.00 42.35  ? 330 THR A N     1 
ATOM   2532  C  CA    . THR A 1 330 ? -65.980 0.007   -5.408   1.00 40.55  ? 330 THR A CA    1 
ATOM   2533  C  C     . THR A 1 330 ? -64.791 0.055   -6.357   1.00 39.69  ? 330 THR A C     1 
ATOM   2534  O  O     . THR A 1 330 ? -64.837 0.771   -7.349   1.00 41.18  ? 330 THR A O     1 
ATOM   2535  C  CB    . THR A 1 330 ? -65.699 0.847   -4.156   1.00 41.88  ? 330 THR A CB    1 
ATOM   2536  O  OG1   . THR A 1 330 ? -66.799 0.696   -3.276   1.00 44.12  ? 330 THR A OG1   1 
ATOM   2537  C  CG2   . THR A 1 330 ? -65.474 2.314   -4.449   1.00 43.50  ? 330 THR A CG2   1 
ATOM   2538  N  N     . LEU A 1 331 ? -63.743 -0.729  -6.070   1.00 38.30  ? 331 LEU A N     1 
ATOM   2539  C  CA    . LEU A 1 331 ? -62.549 -0.680  -6.898   1.00 41.89  ? 331 LEU A CA    1 
ATOM   2540  C  C     . LEU A 1 331 ? -62.864 -1.220  -8.289   1.00 39.51  ? 331 LEU A C     1 
ATOM   2541  O  O     . LEU A 1 331 ? -62.305 -0.750  -9.283   1.00 36.10  ? 331 LEU A O     1 
ATOM   2542  C  CB    . LEU A 1 331 ? -61.427 -1.499  -6.255   1.00 44.54  ? 331 LEU A CB    1 
ATOM   2543  C  CG    . LEU A 1 331 ? -60.878 -1.015  -4.919   1.00 44.54  ? 331 LEU A CG    1 
ATOM   2544  C  CD1   . LEU A 1 331 ? -59.769 -1.940  -4.473   1.00 43.80  ? 331 LEU A CD1   1 
ATOM   2545  C  CD2   . LEU A 1 331 ? -60.372 0.426   -5.001   1.00 47.38  ? 331 LEU A CD2   1 
ATOM   2546  N  N     . TRP A 1 332 ? -63.743 -2.229  -8.348   1.00 43.82  ? 332 TRP A N     1 
ATOM   2547  C  CA    . TRP A 1 332 ? -64.097 -2.850  -9.619   1.00 44.17  ? 332 TRP A CA    1 
ATOM   2548  C  C     . TRP A 1 332 ? -64.862 -1.841  -10.478  1.00 42.44  ? 332 TRP A C     1 
ATOM   2549  O  O     . TRP A 1 332 ? -64.653 -1.762  -11.687  1.00 38.14  ? 332 TRP A O     1 
ATOM   2550  C  CB    . TRP A 1 332 ? -64.885 -4.158  -9.416   1.00 43.86  ? 332 TRP A CB    1 
ATOM   2551  C  CG    . TRP A 1 332 ? -65.315 -4.796  -10.703  1.00 42.93  ? 332 TRP A CG    1 
ATOM   2552  C  CD1   . TRP A 1 332 ? -66.600 -5.035  -11.117  1.00 43.37  ? 332 TRP A CD1   1 
ATOM   2553  C  CD2   . TRP A 1 332 ? -64.457 -5.232  -11.777  1.00 39.06  ? 332 TRP A CD2   1 
ATOM   2554  N  NE1   . TRP A 1 332 ? -66.595 -5.596  -12.369  1.00 42.74  ? 332 TRP A NE1   1 
ATOM   2555  C  CE2   . TRP A 1 332 ? -65.299 -5.721  -12.802  1.00 42.30  ? 332 TRP A CE2   1 
ATOM   2556  C  CE3   . TRP A 1 332 ? -63.066 -5.297  -11.957  1.00 40.14  ? 332 TRP A CE3   1 
ATOM   2557  C  CZ2   . TRP A 1 332 ? -64.791 -6.242  -13.994  1.00 42.67  ? 332 TRP A CZ2   1 
ATOM   2558  C  CZ3   . TRP A 1 332 ? -62.569 -5.789  -13.144  1.00 40.31  ? 332 TRP A CZ3   1 
ATOM   2559  C  CH2   . TRP A 1 332 ? -63.422 -6.280  -14.134  1.00 38.20  ? 332 TRP A CH2   1 
ATOM   2560  N  N     . THR A 1 333 ? -65.737 -1.045  -9.854   1.00 42.59  ? 333 THR A N     1 
ATOM   2561  C  CA    . THR A 1 333 ? -66.464 -0.020  -10.589  1.00 42.63  ? 333 THR A CA    1 
ATOM   2562  C  C     . THR A 1 333 ? -65.472 0.877   -11.324  1.00 41.50  ? 333 THR A C     1 
ATOM   2563  O  O     . THR A 1 333 ? -65.660 1.186   -12.495  1.00 40.92  ? 333 THR A O     1 
ATOM   2564  C  CB    . THR A 1 333 ? -67.424 0.751   -9.666   1.00 47.37  ? 333 THR A CB    1 
ATOM   2565  O  OG1   . THR A 1 333 ? -68.400 -0.194  -9.236   1.00 47.59  ? 333 THR A OG1   1 
ATOM   2566  C  CG2   . THR A 1 333 ? -68.137 1.906   -10.334  1.00 44.77  ? 333 THR A CG2   1 
ATOM   2567  N  N     . ALA A 1 334 ? -64.400 1.281   -10.641  1.00 36.70  ? 334 ALA A N     1 
ATOM   2568  C  CA    . ALA A 1 334 ? -63.432 2.191   -11.230  1.00 37.33  ? 334 ALA A CA    1 
ATOM   2569  C  C     . ALA A 1 334 ? -62.655 1.501   -12.350  1.00 35.70  ? 334 ALA A C     1 
ATOM   2570  O  O     . ALA A 1 334 ? -62.356 2.106   -13.375  1.00 41.68  ? 334 ALA A O     1 
ATOM   2571  C  CB    . ALA A 1 334 ? -62.506 2.689   -10.140  1.00 39.49  ? 334 ALA A CB    1 
ATOM   2572  N  N     . ILE A 1 335 ? -62.281 0.237   -12.137  1.00 39.56  ? 335 ILE A N     1 
ATOM   2573  C  CA    . ILE A 1 335 ? -61.475 -0.490  -13.106  1.00 40.30  ? 335 ILE A CA    1 
ATOM   2574  C  C     . ILE A 1 335 ? -62.309 -0.753  -14.366  1.00 38.87  ? 335 ILE A C     1 
ATOM   2575  O  O     . ILE A 1 335 ? -61.862 -0.485  -15.471  1.00 40.29  ? 335 ILE A O     1 
ATOM   2576  C  CB    . ILE A 1 335 ? -60.924 -1.780  -12.465  1.00 36.96  ? 335 ILE A CB    1 
ATOM   2577  C  CG1   . ILE A 1 335 ? -59.898 -1.472  -11.371  1.00 40.32  ? 335 ILE A CG1   1 
ATOM   2578  C  CG2   . ILE A 1 335 ? -60.353 -2.712  -13.506  1.00 35.28  ? 335 ILE A CG2   1 
ATOM   2579  C  CD1   . ILE A 1 335 ? -59.627 -2.632  -10.403  1.00 40.58  ? 335 ILE A CD1   1 
ATOM   2580  N  N     . ARG A 1 336 ? -63.517 -1.289  -14.194  1.00 39.42  ? 336 ARG A N     1 
ATOM   2581  C  CA    . ARG A 1 336 ? -64.376 -1.646  -15.316  1.00 42.73  ? 336 ARG A CA    1 
ATOM   2582  C  C     . ARG A 1 336 ? -64.768 -0.407  -16.117  1.00 41.61  ? 336 ARG A C     1 
ATOM   2583  O  O     . ARG A 1 336 ? -64.715 -0.402  -17.339  1.00 42.55  ? 336 ARG A O     1 
ATOM   2584  C  CB    . ARG A 1 336 ? -65.651 -2.334  -14.833  1.00 42.71  ? 336 ARG A CB    1 
ATOM   2585  C  CG    . ARG A 1 336 ? -66.462 -2.937  -15.968  1.00 46.62  ? 336 ARG A CG    1 
ATOM   2586  C  CD    . ARG A 1 336 ? -67.842 -3.406  -15.552  1.00 52.95  ? 336 ARG A CD    1 
ATOM   2587  N  NE    . ARG A 1 336 ? -68.697 -3.489  -16.730  1.00 63.24  ? 336 ARG A NE    1 
ATOM   2588  C  CZ    . ARG A 1 336 ? -69.082 -4.617  -17.306  1.00 62.24  ? 336 ARG A CZ    1 
ATOM   2589  N  NH1   . ARG A 1 336 ? -68.776 -5.782  -16.762  1.00 67.83  ? 336 ARG A NH1   1 
ATOM   2590  N  NH2   . ARG A 1 336 ? -69.771 -4.577  -18.431  1.00 61.81  ? 336 ARG A NH2   1 
ATOM   2591  N  N     . ASP A 1 337 ? -65.163 0.659   -15.424  1.00 44.03  ? 337 ASP A N     1 
ATOM   2592  C  CA    . ASP A 1 337 ? -65.484 1.911   -16.098  1.00 44.21  ? 337 ASP A CA    1 
ATOM   2593  C  C     . ASP A 1 337 ? -64.301 2.431   -16.898  1.00 41.46  ? 337 ASP A C     1 
ATOM   2594  O  O     . ASP A 1 337 ? -64.517 3.102   -17.887  1.00 41.61  ? 337 ASP A O     1 
ATOM   2595  C  CB    . ASP A 1 337 ? -65.893 3.009   -15.126  1.00 44.54  ? 337 ASP A CB    1 
ATOM   2596  C  CG    . ASP A 1 337 ? -67.266 2.804   -14.534  1.00 48.83  ? 337 ASP A CG    1 
ATOM   2597  O  OD1   . ASP A 1 337 ? -67.938 1.836   -14.932  1.00 46.44  ? 337 ASP A OD1   1 
ATOM   2598  O  OD2   . ASP A 1 337 ? -67.626 3.605   -13.656  1.00 58.88  ? 337 ASP A OD2   1 
ATOM   2599  N  N     . SER A 1 338 ? -63.061 2.162   -16.457  1.00 40.21  ? 338 SER A N     1 
ATOM   2600  C  CA    . SER A 1 338 ? -61.896 2.651   -17.186  1.00 40.36  ? 338 SER A CA    1 
ATOM   2601  C  C     . SER A 1 338 ? -61.735 1.992   -18.559  1.00 38.30  ? 338 SER A C     1 
ATOM   2602  O  O     . SER A 1 338 ? -61.047 2.549   -19.409  1.00 42.35  ? 338 SER A O     1 
ATOM   2603  C  CB    . SER A 1 338 ? -60.641 2.478   -16.379  1.00 41.49  ? 338 SER A CB    1 
ATOM   2604  O  OG    . SER A 1 338 ? -60.789 3.046   -15.095  1.00 40.54  ? 338 SER A OG    1 
ATOM   2605  N  N     . PHE A 1 339 ? -62.356 0.821   -18.783  1.00 37.83  ? 339 PHE A N     1 
ATOM   2606  C  CA    . PHE A 1 339 ? -62.160 0.059   -20.009  1.00 37.10  ? 339 PHE A CA    1 
ATOM   2607  C  C     . PHE A 1 339 ? -63.440 -0.211  -20.807  1.00 36.88  ? 339 PHE A C     1 
ATOM   2608  O  O     . PHE A 1 339 ? -63.346 -0.653  -21.948  1.00 39.68  ? 339 PHE A O     1 
ATOM   2609  C  CB    . PHE A 1 339 ? -61.501 -1.276  -19.656  1.00 38.07  ? 339 PHE A CB    1 
ATOM   2610  C  CG    . PHE A 1 339 ? -60.139 -1.131  -19.028  1.00 39.34  ? 339 PHE A CG    1 
ATOM   2611  C  CD1   . PHE A 1 339 ? -59.050 -0.745  -19.780  1.00 35.84  ? 339 PHE A CD1   1 
ATOM   2612  C  CD2   . PHE A 1 339 ? -59.963 -1.347  -17.671  1.00 39.83  ? 339 PHE A CD2   1 
ATOM   2613  C  CE1   . PHE A 1 339 ? -57.806 -0.594  -19.183  1.00 41.78  ? 339 PHE A CE1   1 
ATOM   2614  C  CE2   . PHE A 1 339 ? -58.722 -1.205  -17.079  1.00 36.90  ? 339 PHE A CE2   1 
ATOM   2615  C  CZ    . PHE A 1 339 ? -57.644 -0.821  -17.833  1.00 40.85  ? 339 PHE A CZ    1 
ATOM   2616  N  N     . ALA A 1 340 ? -64.628 0.056   -20.249  1.00 39.68  ? 340 ALA A N     1 
ATOM   2617  C  CA    . ALA A 1 340 ? -65.874 -0.426  -20.831  1.00 42.35  ? 340 ALA A CA    1 
ATOM   2618  C  C     . ALA A 1 340 ? -66.124 0.123   -22.236  1.00 48.64  ? 340 ALA A C     1 
ATOM   2619  O  O     . ALA A 1 340 ? -66.802 -0.529  -23.016  1.00 51.34  ? 340 ALA A O     1 
ATOM   2620  C  CB    . ALA A 1 340 ? -67.052 -0.121  -19.938  1.00 42.51  ? 340 ALA A CB    1 
ATOM   2621  N  N     . ASP A 1 341 ? -65.626 1.317   -22.560  1.00 45.64  ? 341 ASP A N     1 
ATOM   2622  C  CA    . ASP A 1 341 ? -65.987 1.935   -23.823  1.00 46.97  ? 341 ASP A CA    1 
ATOM   2623  C  C     . ASP A 1 341 ? -65.065 1.483   -24.955  1.00 44.72  ? 341 ASP A C     1 
ATOM   2624  O  O     . ASP A 1 341 ? -65.213 1.957   -26.062  1.00 44.69  ? 341 ASP A O     1 
ATOM   2625  C  CB    . ASP A 1 341 ? -65.993 3.467   -23.726  1.00 47.05  ? 341 ASP A CB    1 
ATOM   2626  C  CG    . ASP A 1 341 ? -64.655 4.144   -23.477  1.00 53.73  ? 341 ASP A CG    1 
ATOM   2627  O  OD1   . ASP A 1 341 ? -63.632 3.465   -23.444  1.00 54.12  ? 341 ASP A OD1   1 
ATOM   2628  O  OD2   . ASP A 1 341 ? -64.657 5.368   -23.290  1.00 69.86  ? 341 ASP A OD2   1 
ATOM   2629  N  N     . ILE A 1 342 ? -64.093 0.606   -24.703  1.00 39.70  ? 342 ILE A N     1 
ATOM   2630  C  CA    . ILE A 1 342 ? -63.210 0.143   -25.770  1.00 44.72  ? 342 ILE A CA    1 
ATOM   2631  C  C     . ILE A 1 342 ? -63.902 -0.935  -26.611  1.00 44.94  ? 342 ILE A C     1 
ATOM   2632  O  O     . ILE A 1 342 ? -64.170 -2.022  -26.099  1.00 42.54  ? 342 ILE A O     1 
ATOM   2633  C  CB    . ILE A 1 342 ? -61.900 -0.412  -25.174  1.00 46.42  ? 342 ILE A CB    1 
ATOM   2634  C  CG1   . ILE A 1 342 ? -61.153 0.637   -24.349  1.00 46.28  ? 342 ILE A CG1   1 
ATOM   2635  C  CG2   . ILE A 1 342 ? -61.017 -1.026  -26.250  1.00 47.75  ? 342 ILE A CG2   1 
ATOM   2636  C  CD1   . ILE A 1 342 ? -60.089 0.038   -23.463  1.00 46.09  ? 342 ILE A CD1   1 
ATOM   2637  N  N     . PRO A 1 343 ? -64.129 -0.730  -27.933  1.00 44.97  ? 343 PRO A N     1 
ATOM   2638  C  CA    . PRO A 1 343 ? -64.791 -1.744  -28.765  1.00 43.91  ? 343 PRO A CA    1 
ATOM   2639  C  C     . PRO A 1 343 ? -64.142 -3.129  -28.650  1.00 41.11  ? 343 PRO A C     1 
ATOM   2640  O  O     . PRO A 1 343 ? -62.919 -3.248  -28.708  1.00 42.76  ? 343 PRO A O     1 
ATOM   2641  C  CB    . PRO A 1 343 ? -64.659 -1.185  -30.197  1.00 42.13  ? 343 PRO A CB    1 
ATOM   2642  C  CG    . PRO A 1 343 ? -64.513 0.316   -30.010  1.00 44.86  ? 343 PRO A CG    1 
ATOM   2643  C  CD    . PRO A 1 343 ? -63.762 0.473   -28.701  1.00 45.77  ? 343 PRO A CD    1 
ATOM   2644  N  N     . GLY A 1 344 ? -64.971 -4.164  -28.433  1.00 40.41  ? 344 GLY A N     1 
ATOM   2645  C  CA    . GLY A 1 344 ? -64.539 -5.552  -28.336  1.00 38.59  ? 344 GLY A CA    1 
ATOM   2646  C  C     . GLY A 1 344 ? -64.145 -5.979  -26.915  1.00 43.86  ? 344 GLY A C     1 
ATOM   2647  O  O     . GLY A 1 344 ? -63.802 -7.139  -26.677  1.00 44.73  ? 344 GLY A O     1 
ATOM   2648  N  N     . VAL A 1 345 ? -64.166 -5.056  -25.946  1.00 46.00  ? 345 VAL A N     1 
ATOM   2649  C  CA    . VAL A 1 345 ? -63.667 -5.400  -24.623  1.00 47.10  ? 345 VAL A CA    1 
ATOM   2650  C  C     . VAL A 1 345 ? -64.583 -6.448  -23.992  1.00 39.99  ? 345 VAL A C     1 
ATOM   2651  O  O     . VAL A 1 345 ? -65.773 -6.382  -24.165  1.00 37.16  ? 345 VAL A O     1 
ATOM   2652  C  CB    . VAL A 1 345 ? -63.569 -4.172  -23.699  1.00 46.21  ? 345 VAL A CB    1 
ATOM   2653  C  CG1   . VAL A 1 345 ? -64.941 -3.607  -23.360  1.00 44.08  ? 345 VAL A CG1   1 
ATOM   2654  C  CG2   . VAL A 1 345 ? -62.819 -4.514  -22.426  1.00 46.29  ? 345 VAL A CG2   1 
ATOM   2655  N  N     . LYS A 1 346 ? -64.031 -7.374  -23.206  1.00 42.56  ? 346 LYS A N     1 
ATOM   2656  C  CA    . LYS A 1 346 ? -64.853 -8.313  -22.467  1.00 42.06  ? 346 LYS A CA    1 
ATOM   2657  C  C     . LYS A 1 346 ? -64.282 -8.476  -21.065  1.00 42.99  ? 346 LYS A C     1 
ATOM   2658  O  O     . LYS A 1 346 ? -63.063 -8.460  -20.885  1.00 37.94  ? 346 LYS A O     1 
ATOM   2659  C  CB    . LYS A 1 346 ? -64.930 -9.642  -23.226  1.00 48.91  ? 346 LYS A CB    1 
ATOM   2660  C  CG    . LYS A 1 346 ? -65.521 -9.515  -24.627  1.00 51.31  ? 346 LYS A CG    1 
ATOM   2661  C  CD    . LYS A 1 346 ? -66.155 -10.798 -25.150  1.00 62.29  ? 346 LYS A CD    1 
ATOM   2662  C  CE    . LYS A 1 346 ? -66.872 -10.614 -26.471  1.00 67.92  ? 346 LYS A CE    1 
ATOM   2663  N  NZ    . LYS A 1 346 ? -65.953 -10.103 -27.522  1.00 79.97  ? 346 LYS A NZ    1 
ATOM   2664  N  N     . PHE A 1 347 ? -65.183 -8.639  -20.089  1.00 42.73  ? 347 PHE A N     1 
ATOM   2665  C  CA    . PHE A 1 347 ? -64.826 -8.697  -18.682  1.00 45.23  ? 347 PHE A CA    1 
ATOM   2666  C  C     . PHE A 1 347 ? -65.244 -10.053 -18.136  1.00 42.96  ? 347 PHE A C     1 
ATOM   2667  O  O     . PHE A 1 347 ? -66.395 -10.427 -18.327  1.00 43.87  ? 347 PHE A O     1 
ATOM   2668  C  CB    . PHE A 1 347 ? -65.551 -7.592  -17.913  1.00 44.76  ? 347 PHE A CB    1 
ATOM   2669  C  CG    . PHE A 1 347 ? -65.275 -6.183  -18.377  1.00 41.97  ? 347 PHE A CG    1 
ATOM   2670  C  CD1   . PHE A 1 347 ? -64.165 -5.488  -17.912  1.00 40.54  ? 347 PHE A CD1   1 
ATOM   2671  C  CD2   . PHE A 1 347 ? -66.114 -5.555  -19.284  1.00 43.17  ? 347 PHE A CD2   1 
ATOM   2672  C  CE1   . PHE A 1 347 ? -63.933 -4.179  -18.308  1.00 41.89  ? 347 PHE A CE1   1 
ATOM   2673  C  CE2   . PHE A 1 347 ? -65.875 -4.245  -19.687  1.00 46.39  ? 347 PHE A CE2   1 
ATOM   2674  C  CZ    . PHE A 1 347 ? -64.782 -3.564  -19.204  1.00 44.49  ? 347 PHE A CZ    1 
ATOM   2675  N  N     . TYR A 1 348 ? -64.318 -10.753 -17.460  1.00 40.14  ? 348 TYR A N     1 
ATOM   2676  C  CA    . TYR A 1 348 ? -64.596 -12.054 -16.866  1.00 39.78  ? 348 TYR A CA    1 
ATOM   2677  C  C     . TYR A 1 348 ? -64.152 -12.179 -15.403  1.00 38.98  ? 348 TYR A C     1 
ATOM   2678  O  O     . TYR A 1 348 ? -63.017 -11.857 -15.034  1.00 37.71  ? 348 TYR A O     1 
ATOM   2679  C  CB    . TYR A 1 348 ? -63.853 -13.149 -17.634  1.00 40.95  ? 348 TYR A CB    1 
ATOM   2680  C  CG    . TYR A 1 348 ? -64.107 -13.207 -19.118  1.00 42.34  ? 348 TYR A CG    1 
ATOM   2681  C  CD1   . TYR A 1 348 ? -63.275 -12.533 -20.004  1.00 41.44  ? 348 TYR A CD1   1 
ATOM   2682  C  CD2   . TYR A 1 348 ? -65.129 -13.996 -19.644  1.00 44.51  ? 348 TYR A CD2   1 
ATOM   2683  C  CE1   . TYR A 1 348 ? -63.461 -12.618 -21.374  1.00 43.81  ? 348 TYR A CE1   1 
ATOM   2684  C  CE2   . TYR A 1 348 ? -65.338 -14.079 -21.013  1.00 42.64  ? 348 TYR A CE2   1 
ATOM   2685  C  CZ    . TYR A 1 348 ? -64.504 -13.382 -21.877  1.00 44.53  ? 348 TYR A CZ    1 
ATOM   2686  O  OH    . TYR A 1 348 ? -64.673 -13.427 -23.236  1.00 42.06  ? 348 TYR A OH    1 
ATOM   2687  N  N     . PHE A 1 349 ? -65.043 -12.745 -14.573  1.00 35.97  ? 349 PHE A N     1 
ATOM   2688  C  CA    . PHE A 1 349 ? -64.678 -13.367 -13.309  1.00 37.79  ? 349 PHE A CA    1 
ATOM   2689  C  C     . PHE A 1 349 ? -64.590 -14.889 -13.516  1.00 39.29  ? 349 PHE A C     1 
ATOM   2690  O  O     . PHE A 1 349 ? -64.983 -15.394 -14.571  1.00 39.07  ? 349 PHE A O     1 
ATOM   2691  C  CB    . PHE A 1 349 ? -65.672 -12.882 -12.243  1.00 40.21  ? 349 PHE A CB    1 
ATOM   2692  C  CG    . PHE A 1 349 ? -65.420 -11.445 -11.856  1.00 43.43  ? 349 PHE A CG    1 
ATOM   2693  C  CD1   . PHE A 1 349 ? -64.390 -11.127 -10.979  1.00 44.81  ? 349 PHE A CD1   1 
ATOM   2694  C  CD2   . PHE A 1 349 ? -66.157 -10.413 -12.410  1.00 42.95  ? 349 PHE A CD2   1 
ATOM   2695  C  CE1   . PHE A 1 349 ? -64.137 -9.810  -10.631  1.00 44.45  ? 349 PHE A CE1   1 
ATOM   2696  C  CE2   . PHE A 1 349 ? -65.890 -9.091  -12.083  1.00 46.92  ? 349 PHE A CE2   1 
ATOM   2697  C  CZ    . PHE A 1 349 ? -64.879 -8.792  -11.197  1.00 50.47  ? 349 PHE A CZ    1 
ATOM   2698  N  N     . PRO A 1 350 ? -64.059 -15.695 -12.563  1.00 40.49  ? 350 PRO A N     1 
ATOM   2699  C  CA    . PRO A 1 350 ? -63.899 -17.141 -12.785  1.00 41.67  ? 350 PRO A CA    1 
ATOM   2700  C  C     . PRO A 1 350 ? -65.162 -17.839 -13.270  1.00 42.69  ? 350 PRO A C     1 
ATOM   2701  O  O     . PRO A 1 350 ? -65.120 -18.573 -14.242  1.00 41.83  ? 350 PRO A O     1 
ATOM   2702  C  CB    . PRO A 1 350 ? -63.468 -17.662 -11.415  1.00 39.36  ? 350 PRO A CB    1 
ATOM   2703  C  CG    . PRO A 1 350 ? -62.689 -16.489 -10.864  1.00 41.97  ? 350 PRO A CG    1 
ATOM   2704  C  CD    . PRO A 1 350 ? -63.526 -15.289 -11.255  1.00 38.87  ? 350 PRO A CD    1 
ATOM   2705  N  N     . GLU A 1 351 ? -66.293 -17.542 -12.635  1.00 45.35  ? 351 GLU A N     1 
ATOM   2706  C  CA    . GLU A 1 351 ? -67.552 -18.180 -12.974  1.00 46.18  ? 351 GLU A CA    1 
ATOM   2707  C  C     . GLU A 1 351 ? -67.971 -17.882 -14.411  1.00 48.11  ? 351 GLU A C     1 
ATOM   2708  O  O     . GLU A 1 351 ? -68.831 -18.584 -14.926  1.00 54.36  ? 351 GLU A O     1 
ATOM   2709  C  CB    . GLU A 1 351 ? -68.671 -17.717 -12.036  1.00 44.06  ? 351 GLU A CB    1 
ATOM   2710  C  CG    . GLU A 1 351 ? -69.019 -16.240 -12.161  1.00 44.70  ? 351 GLU A CG    1 
ATOM   2711  C  CD    . GLU A 1 351 ? -68.324 -15.287 -11.193  1.00 50.21  ? 351 GLU A CD    1 
ATOM   2712  O  OE1   . GLU A 1 351 ? -67.300 -15.656 -10.583  1.00 44.89  ? 351 GLU A OE1   1 
ATOM   2713  O  OE2   . GLU A 1 351 ? -68.832 -14.173 -11.023  1.00 56.01  ? 351 GLU A OE2   1 
ATOM   2714  N  N     . ASP A 1 352 ? -67.438 -16.820 -15.043  1.00 47.30  ? 352 ASP A N     1 
ATOM   2715  C  CA    . ASP A 1 352 ? -67.837 -16.485 -16.400  1.00 41.40  ? 352 ASP A CA    1 
ATOM   2716  C  C     . ASP A 1 352 ? -67.001 -17.232 -17.435  1.00 42.09  ? 352 ASP A C     1 
ATOM   2717  O  O     . ASP A 1 352 ? -67.244 -17.068 -18.619  1.00 50.25  ? 352 ASP A O     1 
ATOM   2718  C  CB    . ASP A 1 352 ? -67.706 -14.987 -16.709  1.00 47.91  ? 352 ASP A CB    1 
ATOM   2719  C  CG    . ASP A 1 352 ? -68.473 -14.105 -15.749  1.00 45.99  ? 352 ASP A CG    1 
ATOM   2720  O  OD1   . ASP A 1 352 ? -69.650 -14.362 -15.608  1.00 51.04  ? 352 ASP A OD1   1 
ATOM   2721  O  OD2   . ASP A 1 352 ? -67.859 -13.205 -15.113  1.00 48.16  ? 352 ASP A OD2   1 
ATOM   2722  N  N     . ARG A 1 353 ? -65.989 -17.997 -17.019  1.00 45.02  ? 353 ARG A N     1 
ATOM   2723  C  CA    . ARG A 1 353 ? -65.150 -18.699 -17.979  1.00 45.73  ? 353 ARG A CA    1 
ATOM   2724  C  C     . ARG A 1 353 ? -65.795 -20.053 -18.299  1.00 48.75  ? 353 ARG A C     1 
ATOM   2725  O  O     . ARG A 1 353 ? -66.166 -20.813 -17.402  1.00 49.62  ? 353 ARG A O     1 
ATOM   2726  C  CB    . ARG A 1 353 ? -63.726 -18.858 -17.436  1.00 42.85  ? 353 ARG A CB    1 
ATOM   2727  C  CG    . ARG A 1 353 ? -63.065 -17.553 -17.012  1.00 41.07  ? 353 ARG A CG    1 
ATOM   2728  C  CD    . ARG A 1 353 ? -62.856 -16.631 -18.190  1.00 41.01  ? 353 ARG A CD    1 
ATOM   2729  N  NE    . ARG A 1 353 ? -61.814 -17.139 -19.066  1.00 37.41  ? 353 ARG A NE    1 
ATOM   2730  C  CZ    . ARG A 1 353 ? -61.627 -16.735 -20.314  1.00 35.69  ? 353 ARG A CZ    1 
ATOM   2731  N  NH1   . ARG A 1 353 ? -62.389 -15.802 -20.849  1.00 38.08  ? 353 ARG A NH1   1 
ATOM   2732  N  NH2   . ARG A 1 353 ? -60.642 -17.238 -21.019  1.00 39.50  ? 353 ARG A NH2   1 
ATOM   2733  N  N     . ARG A 1 354 ? -65.920 -20.371 -19.586  1.00 47.30  ? 354 ARG A N     1 
ATOM   2734  C  CA    . ARG A 1 354 ? -66.646 -21.571 -19.942  1.00 45.34  ? 354 ARG A CA    1 
ATOM   2735  C  C     . ARG A 1 354 ? -65.708 -22.768 -20.023  1.00 45.86  ? 354 ARG A C     1 
ATOM   2736  O  O     . ARG A 1 354 ? -66.201 -23.882 -20.033  1.00 49.38  ? 354 ARG A O     1 
ATOM   2737  C  CB    . ARG A 1 354 ? -67.488 -21.343 -21.196  1.00 52.63  ? 354 ARG A CB    1 
ATOM   2738  C  CG    . ARG A 1 354 ? -66.705 -21.000 -22.446  1.00 50.87  ? 354 ARG A CG    1 
ATOM   2739  C  CD    . ARG A 1 354 ? -67.655 -20.538 -23.526  1.00 43.99  ? 354 ARG A CD    1 
ATOM   2740  N  NE    . ARG A 1 354 ? -66.856 -20.181 -24.674  1.00 45.15  ? 354 ARG A NE    1 
ATOM   2741  C  CZ    . ARG A 1 354 ? -66.281 -21.040 -25.503  1.00 47.74  ? 354 ARG A CZ    1 
ATOM   2742  N  NH1   . ARG A 1 354 ? -66.634 -22.312 -25.500  1.00 51.25  ? 354 ARG A NH1   1 
ATOM   2743  N  NH2   . ARG A 1 354 ? -65.402 -20.605 -26.389  1.00 49.45  ? 354 ARG A NH2   1 
ATOM   2744  N  N     . HIS A 1 355 ? -64.381 -22.536 -20.016  1.00 43.56  ? 355 HIS A N     1 
ATOM   2745  C  CA    . HIS A 1 355 ? -63.393 -23.598 -19.995  1.00 44.14  ? 355 HIS A CA    1 
ATOM   2746  C  C     . HIS A 1 355 ? -62.967 -23.871 -18.558  1.00 49.69  ? 355 HIS A C     1 
ATOM   2747  O  O     . HIS A 1 355 ? -62.666 -22.931 -17.823  1.00 48.47  ? 355 HIS A O     1 
ATOM   2748  C  CB    . HIS A 1 355 ? -62.143 -23.246 -20.818  1.00 43.05  ? 355 HIS A CB    1 
ATOM   2749  C  CG    . HIS A 1 355 ? -62.478 -22.913 -22.224  1.00 42.77  ? 355 HIS A CG    1 
ATOM   2750  N  ND1   . HIS A 1 355 ? -62.547 -23.839 -23.244  1.00 49.19  ? 355 HIS A ND1   1 
ATOM   2751  C  CD2   . HIS A 1 355 ? -62.759 -21.732 -22.764  1.00 41.57  ? 355 HIS A CD2   1 
ATOM   2752  C  CE1   . HIS A 1 355 ? -62.893 -23.216 -24.358  1.00 45.88  ? 355 HIS A CE1   1 
ATOM   2753  N  NE2   . HIS A 1 355 ? -63.011 -21.930 -24.092  1.00 47.75  ? 355 HIS A NE2   1 
ATOM   2754  N  N     . LYS A 1 356 ? -62.902 -25.165 -18.193  1.00 42.93  ? 356 LYS A N     1 
ATOM   2755  C  CA    . LYS A 1 356 ? -62.568 -25.566 -16.840  1.00 46.33  ? 356 LYS A CA    1 
ATOM   2756  C  C     . LYS A 1 356 ? -61.055 -25.541 -16.639  1.00 45.42  ? 356 LYS A C     1 
ATOM   2757  O  O     . LYS A 1 356 ? -60.584 -25.635 -15.511  1.00 49.78  ? 356 LYS A O     1 
ATOM   2758  C  CB    . LYS A 1 356 ? -63.114 -26.968 -16.568  1.00 50.85  ? 356 LYS A CB    1 
ATOM   2759  C  CG    . LYS A 1 356 ? -64.612 -27.058 -16.321  1.00 55.21  ? 356 LYS A CG    1 
ATOM   2760  C  CD    . LYS A 1 356 ? -64.994 -28.462 -15.839  1.00 61.58  ? 356 LYS A CD    1 
ATOM   2761  C  CE    . LYS A 1 356 ? -66.470 -28.659 -15.550  1.00 66.92  ? 356 LYS A CE    1 
ATOM   2762  N  NZ    . LYS A 1 356 ? -66.775 -28.540 -14.105  1.00 66.94  ? 356 LYS A NZ    1 
ATOM   2763  N  N     . VAL A 1 357 ? -60.309 -25.492 -17.747  1.00 38.79  ? 357 VAL A N     1 
ATOM   2764  C  CA    . VAL A 1 357 ? -58.866 -25.331 -17.749  1.00 40.65  ? 357 VAL A CA    1 
ATOM   2765  C  C     . VAL A 1 357 ? -58.594 -24.101 -18.611  1.00 42.44  ? 357 VAL A C     1 
ATOM   2766  O  O     . VAL A 1 357 ? -58.936 -24.075 -19.787  1.00 40.61  ? 357 VAL A O     1 
ATOM   2767  C  CB    . VAL A 1 357 ? -58.161 -26.598 -18.262  1.00 44.58  ? 357 VAL A CB    1 
ATOM   2768  C  CG1   . VAL A 1 357 ? -56.656 -26.427 -18.289  1.00 47.90  ? 357 VAL A CG1   1 
ATOM   2769  C  CG2   . VAL A 1 357 ? -58.538 -27.818 -17.425  1.00 43.95  ? 357 VAL A CG2   1 
ATOM   2770  N  N     . ASP A 1 358 ? -58.096 -23.042 -17.978  1.00 39.79  ? 358 ASP A N     1 
ATOM   2771  C  CA    . ASP A 1 358 ? -58.330 -21.691 -18.455  1.00 38.13  ? 358 ASP A CA    1 
ATOM   2772  C  C     . ASP A 1 358 ? -57.315 -20.741 -17.826  1.00 40.77  ? 358 ASP A C     1 
ATOM   2773  O  O     . ASP A 1 358 ? -56.882 -20.913 -16.681  1.00 38.35  ? 358 ASP A O     1 
ATOM   2774  C  CB    . ASP A 1 358 ? -59.742 -21.232 -18.105  1.00 41.01  ? 358 ASP A CB    1 
ATOM   2775  C  CG    . ASP A 1 358 ? -60.109 -19.870 -18.669  1.00 43.90  ? 358 ASP A CG    1 
ATOM   2776  O  OD1   . ASP A 1 358 ? -60.482 -19.788 -19.877  1.00 43.12  ? 358 ASP A OD1   1 
ATOM   2777  O  OD2   . ASP A 1 358 ? -59.990 -18.896 -17.903  1.00 43.11  ? 358 ASP A OD2   1 
ATOM   2778  N  N     . LEU A 1 359 ? -56.962 -19.709 -18.580  1.00 44.52  ? 359 LEU A N     1 
ATOM   2779  C  CA    . LEU A 1 359 ? -55.942 -18.790 -18.121  1.00 45.72  ? 359 LEU A CA    1 
ATOM   2780  C  C     . LEU A 1 359 ? -56.375 -18.146 -16.809  1.00 38.30  ? 359 LEU A C     1 
ATOM   2781  O  O     . LEU A 1 359 ? -55.589 -18.079 -15.869  1.00 40.29  ? 359 LEU A O     1 
ATOM   2782  C  CB    . LEU A 1 359 ? -55.661 -17.729 -19.184  1.00 48.59  ? 359 LEU A CB    1 
ATOM   2783  C  CG    . LEU A 1 359 ? -54.763 -16.607 -18.675  1.00 55.20  ? 359 LEU A CG    1 
ATOM   2784  C  CD1   . LEU A 1 359 ? -53.297 -17.007 -18.785  1.00 55.92  ? 359 LEU A CD1   1 
ATOM   2785  C  CD2   . LEU A 1 359 ? -55.065 -15.321 -19.409  1.00 59.76  ? 359 LEU A CD2   1 
ATOM   2786  N  N     . LEU A 1 360 ? -57.616 -17.670 -16.725  1.00 41.35  ? 360 LEU A N     1 
ATOM   2787  C  CA    . LEU A 1 360 ? -58.009 -16.952 -15.518  1.00 42.73  ? 360 LEU A CA    1 
ATOM   2788  C  C     . LEU A 1 360 ? -57.966 -17.897 -14.316  1.00 43.12  ? 360 LEU A C     1 
ATOM   2789  O  O     . LEU A 1 360 ? -57.524 -17.516 -13.230  1.00 45.80  ? 360 LEU A O     1 
ATOM   2790  C  CB    . LEU A 1 360 ? -59.376 -16.282 -15.688  1.00 37.93  ? 360 LEU A CB    1 
ATOM   2791  C  CG    . LEU A 1 360 ? -59.950 -15.675 -14.403  1.00 46.42  ? 360 LEU A CG    1 
ATOM   2792  C  CD1   . LEU A 1 360 ? -59.030 -14.617 -13.809  1.00 49.74  ? 360 LEU A CD1   1 
ATOM   2793  C  CD2   . LEU A 1 360 ? -61.317 -15.078 -14.643  1.00 43.73  ? 360 LEU A CD2   1 
ATOM   2794  N  N     . LEU A 1 361 ? -58.413 -19.141 -14.508  1.00 43.96  ? 361 LEU A N     1 
ATOM   2795  C  CA    . LEU A 1 361 ? -58.473 -20.090 -13.410  1.00 45.74  ? 361 LEU A CA    1 
ATOM   2796  C  C     . LEU A 1 361 ? -57.071 -20.427 -12.928  1.00 42.92  ? 361 LEU A C     1 
ATOM   2797  O  O     . LEU A 1 361 ? -56.874 -20.604 -11.738  1.00 49.42  ? 361 LEU A O     1 
ATOM   2798  C  CB    . LEU A 1 361 ? -59.219 -21.352 -13.850  1.00 45.26  ? 361 LEU A CB    1 
ATOM   2799  C  CG    . LEU A 1 361 ? -60.675 -21.150 -14.262  1.00 50.38  ? 361 LEU A CG    1 
ATOM   2800  C  CD1   . LEU A 1 361 ? -61.372 -22.495 -14.409  1.00 51.08  ? 361 LEU A CD1   1 
ATOM   2801  C  CD2   . LEU A 1 361 ? -61.436 -20.264 -13.279  1.00 51.19  ? 361 LEU A CD2   1 
ATOM   2802  N  N     . HIS A 1 362 ? -56.092 -20.474 -13.842  1.00 43.59  ? 362 HIS A N     1 
ATOM   2803  C  CA    . HIS A 1 362 ? -54.702 -20.649 -13.450  1.00 44.08  ? 362 HIS A CA    1 
ATOM   2804  C  C     . HIS A 1 362 ? -54.185 -19.414 -12.690  1.00 49.21  ? 362 HIS A C     1 
ATOM   2805  O  O     . HIS A 1 362 ? -53.598 -19.536 -11.604  1.00 43.88  ? 362 HIS A O     1 
ATOM   2806  C  CB    . HIS A 1 362 ? -53.853 -20.985 -14.681  1.00 43.04  ? 362 HIS A CB    1 
ATOM   2807  C  CG    . HIS A 1 362 ? -52.428 -20.599 -14.537  1.00 56.49  ? 362 HIS A CG    1 
ATOM   2808  N  ND1   . HIS A 1 362 ? -51.599 -21.090 -13.549  1.00 62.86  ? 362 HIS A ND1   1 
ATOM   2809  C  CD2   . HIS A 1 362 ? -51.687 -19.729 -15.254  1.00 59.56  ? 362 HIS A CD2   1 
ATOM   2810  C  CE1   . HIS A 1 362 ? -50.395 -20.547 -13.687  1.00 57.61  ? 362 HIS A CE1   1 
ATOM   2811  N  NE2   . HIS A 1 362 ? -50.429 -19.720 -14.717  1.00 60.11  ? 362 HIS A NE2   1 
ATOM   2812  N  N     . ARG A 1 363 ? -54.336 -18.224 -13.292  1.00 43.08  ? 363 ARG A N     1 
ATOM   2813  C  CA    . ARG A 1 363 ? -53.778 -16.999 -12.722  1.00 46.47  ? 363 ARG A CA    1 
ATOM   2814  C  C     . ARG A 1 363 ? -54.489 -16.628 -11.411  1.00 42.48  ? 363 ARG A C     1 
ATOM   2815  O  O     . ARG A 1 363 ? -53.847 -16.075 -10.521  1.00 39.92  ? 363 ARG A O     1 
ATOM   2816  C  CB    . ARG A 1 363 ? -53.756 -15.886 -13.778  1.00 46.32  ? 363 ARG A CB    1 
ATOM   2817  C  CG    . ARG A 1 363 ? -52.907 -16.258 -14.987  1.00 54.74  ? 363 ARG A CG    1 
ATOM   2818  C  CD    . ARG A 1 363 ? -52.096 -15.120 -15.570  1.00 63.41  ? 363 ARG A CD    1 
ATOM   2819  N  NE    . ARG A 1 363 ? -51.123 -14.653 -14.588  1.00 66.24  ? 363 ARG A NE    1 
ATOM   2820  C  CZ    . ARG A 1 363 ? -49.971 -15.254 -14.286  1.00 65.80  ? 363 ARG A CZ    1 
ATOM   2821  N  NH1   . ARG A 1 363 ? -49.533 -16.292 -14.983  1.00 67.99  ? 363 ARG A NH1   1 
ATOM   2822  N  NH2   . ARG A 1 363 ? -49.224 -14.765 -13.311  1.00 62.70  ? 363 ARG A NH2   1 
ATOM   2823  N  N     . ALA A 1 364 ? -55.775 -17.007 -11.257  1.00 46.19  ? 364 ALA A N     1 
ATOM   2824  C  CA    . ALA A 1 364 ? -56.486 -16.868 -9.994   1.00 38.67  ? 364 ALA A CA    1 
ATOM   2825  C  C     . ALA A 1 364 ? -55.660 -17.438 -8.842   1.00 48.14  ? 364 ALA A C     1 
ATOM   2826  O  O     . ALA A 1 364 ? -55.591 -16.826 -7.777   1.00 46.39  ? 364 ALA A O     1 
ATOM   2827  C  CB    . ALA A 1 364 ? -57.831 -17.544 -10.039  1.00 39.58  ? 364 ALA A CB    1 
ATOM   2828  N  N     . GLU A 1 365 ? -55.036 -18.610 -9.048   1.00 42.48  ? 365 GLU A N     1 
ATOM   2829  C  CA    . GLU A 1 365 ? -54.211 -19.212 -8.012   1.00 42.77  ? 365 GLU A CA    1 
ATOM   2830  C  C     . GLU A 1 365 ? -52.956 -18.373 -7.753   1.00 41.69  ? 365 GLU A C     1 
ATOM   2831  O  O     . GLU A 1 365 ? -52.598 -18.122 -6.601   1.00 43.84  ? 365 GLU A O     1 
ATOM   2832  C  CB    . GLU A 1 365 ? -53.810 -20.629 -8.424   1.00 48.42  ? 365 GLU A CB    1 
ATOM   2833  C  CG    . GLU A 1 365 ? -54.992 -21.551 -8.648   1.00 50.96  ? 365 GLU A CG    1 
ATOM   2834  C  CD    . GLU A 1 365 ? -55.313 -22.434 -7.465   1.00 62.10  ? 365 GLU A CD    1 
ATOM   2835  O  OE1   . GLU A 1 365 ? -55.716 -21.890 -6.416   1.00 72.11  ? 365 GLU A OE1   1 
ATOM   2836  O  OE2   . GLU A 1 365 ? -55.137 -23.666 -7.595   1.00 82.68  ? 365 GLU A OE2   1 
ATOM   2837  N  N     . THR A 1 366 ? -52.254 -17.977 -8.821   1.00 34.86  ? 366 THR A N     1 
ATOM   2838  C  CA    . THR A 1 366 ? -51.003 -17.243 -8.681   1.00 39.84  ? 366 THR A CA    1 
ATOM   2839  C  C     . THR A 1 366 ? -51.226 -15.920 -7.923   1.00 39.64  ? 366 THR A C     1 
ATOM   2840  O  O     . THR A 1 366 ? -50.392 -15.511 -7.119   1.00 36.10  ? 366 THR A O     1 
ATOM   2841  C  CB    . THR A 1 366 ? -50.371 -16.989 -10.058  1.00 42.38  ? 366 THR A CB    1 
ATOM   2842  O  OG1   . THR A 1 366 ? -50.565 -18.142 -10.875  1.00 48.62  ? 366 THR A OG1   1 
ATOM   2843  C  CG2   . THR A 1 366 ? -48.888 -16.689 -9.976   1.00 43.97  ? 366 THR A CG2   1 
ATOM   2844  N  N     . MET A 1 367 ? -52.363 -15.269 -8.178   1.00 36.42  ? 367 MET A N     1 
ATOM   2845  C  CA    . MET A 1 367 ? -52.652 -13.944 -7.639   1.00 39.50  ? 367 MET A CA    1 
ATOM   2846  C  C     . MET A 1 367 ? -53.167 -14.051 -6.199   1.00 41.54  ? 367 MET A C     1 
ATOM   2847  O  O     . MET A 1 367 ? -53.381 -13.018 -5.561   1.00 37.39  ? 367 MET A O     1 
ATOM   2848  C  CB    . MET A 1 367 ? -53.669 -13.200 -8.513   1.00 35.18  ? 367 MET A CB    1 
ATOM   2849  C  CG    . MET A 1 367 ? -53.097 -12.809 -9.859   1.00 34.15  ? 367 MET A CG    1 
ATOM   2850  S  SD    . MET A 1 367 ? -54.164 -11.792 -10.929  1.00 40.15  ? 367 MET A SD    1 
ATOM   2851  C  CE    . MET A 1 367 ? -55.584 -12.846 -11.208  1.00 45.42  ? 367 MET A CE    1 
ATOM   2852  N  N     . LYS A 1 368 ? -53.333 -15.288 -5.673   1.00 40.72  ? 368 LYS A N     1 
ATOM   2853  C  CA    . LYS A 1 368 ? -53.520 -15.459 -4.238   1.00 42.48  ? 368 LYS A CA    1 
ATOM   2854  C  C     . LYS A 1 368 ? -52.353 -16.218 -3.610   1.00 39.86  ? 368 LYS A C     1 
ATOM   2855  O  O     . LYS A 1 368 ? -52.437 -16.659 -2.466   1.00 44.48  ? 368 LYS A O     1 
ATOM   2856  C  CB    . LYS A 1 368 ? -54.894 -16.043 -3.910   1.00 49.97  ? 368 LYS A CB    1 
ATOM   2857  C  CG    . LYS A 1 368 ? -55.155 -17.468 -4.345   1.00 53.08  ? 368 LYS A CG    1 
ATOM   2858  C  CD    . LYS A 1 368 ? -56.438 -17.969 -3.751   1.00 55.57  ? 368 LYS A CD    1 
ATOM   2859  C  CE    . LYS A 1 368 ? -56.679 -19.431 -4.047   1.00 60.58  ? 368 LYS A CE    1 
ATOM   2860  N  NZ    . LYS A 1 368 ? -57.939 -19.866 -3.407   1.00 64.95  ? 368 LYS A NZ    1 
ATOM   2861  N  N     . GLY A 1 369 ? -51.215 -16.213 -4.301   1.00 36.72  ? 369 GLY A N     1 
ATOM   2862  C  CA    . GLY A 1 369 ? -49.955 -16.721 -3.774   1.00 39.00  ? 369 GLY A CA    1 
ATOM   2863  C  C     . GLY A 1 369 ? -49.895 -18.244 -3.604   1.00 37.72  ? 369 GLY A C     1 
ATOM   2864  O  O     . GLY A 1 369 ? -49.220 -18.714 -2.694   1.00 38.50  ? 369 GLY A O     1 
ATOM   2865  N  N     . VAL A 1 370 ? -50.552 -19.007 -4.489   1.00 35.85  ? 370 VAL A N     1 
ATOM   2866  C  CA    . VAL A 1 370 ? -50.443 -20.467 -4.484   1.00 40.59  ? 370 VAL A CA    1 
ATOM   2867  C  C     . VAL A 1 370 ? -49.368 -20.903 -5.475   1.00 34.23  ? 370 VAL A C     1 
ATOM   2868  O  O     . VAL A 1 370 ? -49.501 -20.668 -6.661   1.00 38.97  ? 370 VAL A O     1 
ATOM   2869  C  CB    . VAL A 1 370 ? -51.770 -21.161 -4.861   1.00 43.37  ? 370 VAL A CB    1 
ATOM   2870  C  CG1   . VAL A 1 370 ? -51.609 -22.684 -4.913   1.00 43.28  ? 370 VAL A CG1   1 
ATOM   2871  C  CG2   . VAL A 1 370 ? -52.905 -20.782 -3.924   1.00 43.85  ? 370 VAL A CG2   1 
ATOM   2872  N  N     . PRO A 1 371 ? -48.290 -21.577 -5.044   1.00 39.03  ? 371 PRO A N     1 
ATOM   2873  C  CA    . PRO A 1 371 ? -47.205 -21.948 -5.948   1.00 44.01  ? 371 PRO A CA    1 
ATOM   2874  C  C     . PRO A 1 371 ? -47.679 -23.055 -6.884   1.00 46.65  ? 371 PRO A C     1 
ATOM   2875  O  O     . PRO A 1 371 ? -48.481 -23.911 -6.496   1.00 41.80  ? 371 PRO A O     1 
ATOM   2876  C  CB    . PRO A 1 371 ? -46.058 -22.394 -5.022   1.00 39.30  ? 371 PRO A CB    1 
ATOM   2877  C  CG    . PRO A 1 371 ? -46.761 -22.819 -3.751   1.00 42.90  ? 371 PRO A CG    1 
ATOM   2878  C  CD    . PRO A 1 371 ? -48.052 -22.035 -3.672   1.00 41.86  ? 371 PRO A CD    1 
ATOM   2879  N  N     . LYS A 1 372 ? -47.194 -22.961 -8.125   1.00 45.27  ? 372 LYS A N     1 
ATOM   2880  C  CA    . LYS A 1 372 ? -47.573 -23.836 -9.216   1.00 49.25  ? 372 LYS A CA    1 
ATOM   2881  C  C     . LYS A 1 372 ? -46.427 -23.847 -10.216  1.00 52.80  ? 372 LYS A C     1 
ATOM   2882  O  O     . LYS A 1 372 ? -45.546 -22.990 -10.135  1.00 44.94  ? 372 LYS A O     1 
ATOM   2883  C  CB    . LYS A 1 372 ? -48.871 -23.347 -9.856   1.00 54.30  ? 372 LYS A CB    1 
ATOM   2884  C  CG    . LYS A 1 372 ? -50.138 -23.854 -9.180   1.00 65.57  ? 372 LYS A CG    1 
ATOM   2885  C  CD    . LYS A 1 372 ? -51.324 -22.934 -9.358   1.00 80.96  ? 372 LYS A CD    1 
ATOM   2886  C  CE    . LYS A 1 372 ? -51.621 -22.535 -10.797  1.00 89.83  ? 372 LYS A CE    1 
ATOM   2887  N  NZ    . LYS A 1 372 ? -52.339 -23.587 -11.567  1.00 87.93  ? 372 LYS A NZ    1 
ATOM   2888  N  N     . LEU A 1 373 ? -46.447 -24.856 -11.103  1.00 51.05  ? 373 LEU A N     1 
ATOM   2889  C  CA    . LEU A 1 373 ? -45.464 -25.003 -12.169  1.00 51.86  ? 373 LEU A CA    1 
ATOM   2890  C  C     . LEU A 1 373 ? -46.127 -24.841 -13.537  1.00 50.28  ? 373 LEU A C     1 
ATOM   2891  O  O     . LEU A 1 373 ? -45.459 -24.829 -14.564  1.00 55.83  ? 373 LEU A O     1 
ATOM   2892  C  CB    . LEU A 1 373 ? -44.822 -26.380 -11.999  1.00 50.91  ? 373 LEU A CB    1 
ATOM   2893  C  CG    . LEU A 1 373 ? -43.975 -26.520 -10.738  1.00 57.14  ? 373 LEU A CG    1 
ATOM   2894  C  CD1   . LEU A 1 373 ? -43.646 -27.976 -10.430  1.00 64.25  ? 373 LEU A CD1   1 
ATOM   2895  C  CD2   . LEU A 1 373 ? -42.693 -25.712 -10.872  1.00 57.92  ? 373 LEU A CD2   1 
ATOM   2896  N  N     . THR A 1 374 ? -47.440 -24.622 -13.519  1.00 46.97  ? 374 THR A N     1 
ATOM   2897  C  CA    . THR A 1 374 ? -48.273 -24.487 -14.697  1.00 47.92  ? 374 THR A CA    1 
ATOM   2898  C  C     . THR A 1 374 ? -47.656 -23.549 -15.734  1.00 51.41  ? 374 THR A C     1 
ATOM   2899  O  O     . THR A 1 374 ? -47.764 -23.827 -16.925  1.00 51.06  ? 374 THR A O     1 
ATOM   2900  C  CB    . THR A 1 374 ? -49.660 -23.954 -14.295  1.00 49.58  ? 374 THR A CB    1 
ATOM   2901  O  OG1   . THR A 1 374 ? -50.199 -24.767 -13.254  1.00 51.69  ? 374 THR A OG1   1 
ATOM   2902  C  CG2   . THR A 1 374 ? -50.650 -23.898 -15.435  1.00 52.03  ? 374 THR A CG2   1 
ATOM   2903  N  N     . GLU A 1 375 ? -47.056 -22.430 -15.299  1.00 49.51  ? 375 GLU A N     1 
ATOM   2904  C  CA    . GLU A 1 375 ? -46.563 -21.427 -16.234  1.00 51.00  ? 375 GLU A CA    1 
ATOM   2905  C  C     . GLU A 1 375 ? -45.528 -22.005 -17.207  1.00 47.67  ? 375 GLU A C     1 
ATOM   2906  O  O     . GLU A 1 375 ? -45.505 -21.633 -18.373  1.00 49.32  ? 375 GLU A O     1 
ATOM   2907  C  CB    . GLU A 1 375 ? -45.964 -20.234 -15.495  1.00 54.49  ? 375 GLU A CB    1 
ATOM   2908  C  CG    . GLU A 1 375 ? -45.697 -19.055 -16.408  1.00 55.36  ? 375 GLU A CG    1 
ATOM   2909  C  CD    . GLU A 1 375 ? -46.942 -18.295 -16.840  1.00 58.40  ? 375 GLU A CD    1 
ATOM   2910  O  OE1   . GLU A 1 375 ? -48.004 -18.513 -16.237  1.00 57.16  ? 375 GLU A OE1   1 
ATOM   2911  O  OE2   . GLU A 1 375 ? -46.844 -17.500 -17.801  1.00 60.96  ? 375 GLU A OE2   1 
ATOM   2912  N  N     . PHE A 1 376 ? -44.684 -22.940 -16.759  1.00 52.57  ? 376 PHE A N     1 
ATOM   2913  C  CA    . PHE A 1 376 ? -43.710 -23.578 -17.639  1.00 52.26  ? 376 PHE A CA    1 
ATOM   2914  C  C     . PHE A 1 376 ? -44.357 -24.225 -18.875  1.00 49.55  ? 376 PHE A C     1 
ATOM   2915  O  O     . PHE A 1 376 ? -43.653 -24.602 -19.797  1.00 44.18  ? 376 PHE A O     1 
ATOM   2916  C  CB    . PHE A 1 376 ? -42.921 -24.666 -16.906  1.00 56.37  ? 376 PHE A CB    1 
ATOM   2917  C  CG    . PHE A 1 376 ? -41.830 -24.176 -15.991  1.00 66.67  ? 376 PHE A CG    1 
ATOM   2918  C  CD1   . PHE A 1 376 ? -42.137 -23.504 -14.820  1.00 73.61  ? 376 PHE A CD1   1 
ATOM   2919  C  CD2   . PHE A 1 376 ? -40.496 -24.411 -16.289  1.00 73.83  ? 376 PHE A CD2   1 
ATOM   2920  C  CE1   . PHE A 1 376 ? -41.136 -23.064 -13.975  1.00 74.22  ? 376 PHE A CE1   1 
ATOM   2921  C  CE2   . PHE A 1 376 ? -39.494 -23.978 -15.438  1.00 73.01  ? 376 PHE A CE2   1 
ATOM   2922  C  CZ    . PHE A 1 376 ? -39.819 -23.304 -14.286  1.00 79.70  ? 376 PHE A CZ    1 
ATOM   2923  N  N     . ASN A 1 377 ? -45.689 -24.356 -18.910  1.00 45.78  ? 377 ASN A N     1 
ATOM   2924  C  CA    . ASN A 1 377 ? -46.407 -24.838 -20.081  1.00 43.96  ? 377 ASN A CA    1 
ATOM   2925  C  C     . ASN A 1 377 ? -46.058 -24.103 -21.378  1.00 43.59  ? 377 ASN A C     1 
ATOM   2926  O  O     . ASN A 1 377 ? -45.966 -24.731 -22.440  1.00 35.51  ? 377 ASN A O     1 
ATOM   2927  C  CB    . ASN A 1 377 ? -47.912 -24.755 -19.854  1.00 47.34  ? 377 ASN A CB    1 
ATOM   2928  C  CG    . ASN A 1 377 ? -48.423 -25.883 -18.981  1.00 49.88  ? 377 ASN A CG    1 
ATOM   2929  O  OD1   . ASN A 1 377 ? -47.653 -26.719 -18.514  1.00 50.08  ? 377 ASN A OD1   1 
ATOM   2930  N  ND2   . ASN A 1 377 ? -49.722 -25.903 -18.747  1.00 47.96  ? 377 ASN A ND2   1 
ATOM   2931  N  N     . PHE A 1 378 ? -45.857 -22.784 -21.304  1.00 38.87  ? 378 PHE A N     1 
ATOM   2932  C  CA    . PHE A 1 378 ? -45.600 -22.011 -22.506  1.00 41.63  ? 378 PHE A CA    1 
ATOM   2933  C  C     . PHE A 1 378 ? -44.341 -22.494 -23.233  1.00 39.33  ? 378 PHE A C     1 
ATOM   2934  O  O     . PHE A 1 378 ? -44.212 -22.265 -24.429  1.00 43.98  ? 378 PHE A O     1 
ATOM   2935  C  CB    . PHE A 1 378 ? -45.600 -20.514 -22.185  1.00 42.66  ? 378 PHE A CB    1 
ATOM   2936  C  CG    . PHE A 1 378 ? -44.393 -19.921 -21.500  1.00 43.41  ? 378 PHE A CG    1 
ATOM   2937  C  CD1   . PHE A 1 378 ? -43.180 -19.809 -22.150  1.00 44.40  ? 378 PHE A CD1   1 
ATOM   2938  C  CD2   . PHE A 1 378 ? -44.513 -19.349 -20.245  1.00 44.09  ? 378 PHE A CD2   1 
ATOM   2939  C  CE1   . PHE A 1 378 ? -42.099 -19.200 -21.532  1.00 47.29  ? 378 PHE A CE1   1 
ATOM   2940  C  CE2   . PHE A 1 378 ? -43.431 -18.741 -19.631  1.00 43.49  ? 378 PHE A CE2   1 
ATOM   2941  C  CZ    . PHE A 1 378 ? -42.227 -18.671 -20.271  1.00 44.60  ? 378 PHE A CZ    1 
ATOM   2942  N  N     . LEU A 1 379 ? -43.438 -23.175 -22.519  1.00 39.14  ? 379 LEU A N     1 
ATOM   2943  C  CA    . LEU A 1 379 ? -42.253 -23.781 -23.107  1.00 43.95  ? 379 LEU A CA    1 
ATOM   2944  C  C     . LEU A 1 379 ? -42.587 -24.901 -24.090  1.00 43.46  ? 379 LEU A C     1 
ATOM   2945  O  O     . LEU A 1 379 ? -41.699 -25.333 -24.827  1.00 38.75  ? 379 LEU A O     1 
ATOM   2946  C  CB    . LEU A 1 379 ? -41.388 -24.361 -21.985  1.00 42.57  ? 379 LEU A CB    1 
ATOM   2947  C  CG    . LEU A 1 379 ? -40.768 -23.330 -21.048  1.00 42.13  ? 379 LEU A CG    1 
ATOM   2948  C  CD1   . LEU A 1 379 ? -39.883 -24.010 -20.030  1.00 43.02  ? 379 LEU A CD1   1 
ATOM   2949  C  CD2   . LEU A 1 379 ? -39.965 -22.301 -21.840  1.00 47.60  ? 379 LEU A CD2   1 
ATOM   2950  N  N     . ASN A 1 380 ? -43.845 -25.366 -24.097  1.00 42.41  ? 380 ASN A N     1 
ATOM   2951  C  CA    . ASN A 1 380 ? -44.261 -26.432 -24.995  1.00 46.18  ? 380 ASN A CA    1 
ATOM   2952  C  C     . ASN A 1 380 ? -44.831 -25.856 -26.270  1.00 44.11  ? 380 ASN A C     1 
ATOM   2953  O  O     . ASN A 1 380 ? -45.205 -26.615 -27.151  1.00 41.74  ? 380 ASN A O     1 
ATOM   2954  C  CB    . ASN A 1 380 ? -45.316 -27.354 -24.385  1.00 48.91  ? 380 ASN A CB    1 
ATOM   2955  C  CG    . ASN A 1 380 ? -44.762 -28.149 -23.227  1.00 49.79  ? 380 ASN A CG    1 
ATOM   2956  O  OD1   . ASN A 1 380 ? -43.576 -28.467 -23.205  1.00 47.97  ? 380 ASN A OD1   1 
ATOM   2957  N  ND2   . ASN A 1 380 ? -45.596 -28.412 -22.238  1.00 53.44  ? 380 ASN A ND2   1 
ATOM   2958  N  N     . TRP A 1 381 ? -44.893 -24.522 -26.370  1.00 43.01  ? 381 TRP A N     1 
ATOM   2959  C  CA    . TRP A 1 381 ? -45.555 -23.899 -27.503  1.00 40.29  ? 381 TRP A CA    1 
ATOM   2960  C  C     . TRP A 1 381 ? -45.110 -24.471 -28.855  1.00 44.86  ? 381 TRP A C     1 
ATOM   2961  O  O     . TRP A 1 381 ? -45.952 -24.652 -29.725  1.00 39.78  ? 381 TRP A O     1 
ATOM   2962  C  CB    . TRP A 1 381 ? -45.358 -22.381 -27.483  1.00 40.62  ? 381 TRP A CB    1 
ATOM   2963  C  CG    . TRP A 1 381 ? -45.992 -21.733 -28.673  1.00 40.28  ? 381 TRP A CG    1 
ATOM   2964  C  CD1   . TRP A 1 381 ? -45.341 -21.188 -29.744  1.00 37.04  ? 381 TRP A CD1   1 
ATOM   2965  C  CD2   . TRP A 1 381 ? -47.401 -21.614 -28.953  1.00 42.95  ? 381 TRP A CD2   1 
ATOM   2966  N  NE1   . TRP A 1 381 ? -46.252 -20.701 -30.644  1.00 41.01  ? 381 TRP A NE1   1 
ATOM   2967  C  CE2   . TRP A 1 381 ? -47.518 -20.942 -30.190  1.00 39.01  ? 381 TRP A CE2   1 
ATOM   2968  C  CE3   . TRP A 1 381 ? -48.570 -22.003 -28.290  1.00 43.41  ? 381 TRP A CE3   1 
ATOM   2969  C  CZ2   . TRP A 1 381 ? -48.748 -20.661 -30.772  1.00 40.64  ? 381 TRP A CZ2   1 
ATOM   2970  C  CZ3   . TRP A 1 381 ? -49.789 -21.722 -28.862  1.00 38.54  ? 381 TRP A CZ3   1 
ATOM   2971  C  CH2   . TRP A 1 381 ? -49.874 -21.049 -30.083  1.00 41.71  ? 381 TRP A CH2   1 
ATOM   2972  N  N     . ASP A 1 382 ? -43.795 -24.696 -29.049  1.00 44.15  ? 382 ASP A N     1 
ATOM   2973  C  CA    . ASP A 1 382 ? -43.265 -25.171 -30.319  1.00 46.32  ? 382 ASP A CA    1 
ATOM   2974  C  C     . ASP A 1 382 ? -42.579 -26.526 -30.134  1.00 45.64  ? 382 ASP A C     1 
ATOM   2975  O  O     . ASP A 1 382 ? -41.569 -26.795 -30.768  1.00 44.84  ? 382 ASP A O     1 
ATOM   2976  C  CB    . ASP A 1 382 ? -42.272 -24.166 -30.912  1.00 54.31  ? 382 ASP A CB    1 
ATOM   2977  C  CG    . ASP A 1 382 ? -42.036 -24.337 -32.408  1.00 64.22  ? 382 ASP A CG    1 
ATOM   2978  O  OD1   . ASP A 1 382 ? -42.738 -25.163 -33.027  1.00 64.48  ? 382 ASP A OD1   1 
ATOM   2979  O  OD2   . ASP A 1 382 ? -41.151 -23.648 -32.948  1.00 73.37  ? 382 ASP A OD2   1 
ATOM   2980  N  N     . GLY A 1 383 ? -43.099 -27.342 -29.216  1.00 46.94  ? 383 GLY A N     1 
ATOM   2981  C  CA    . GLY A 1 383 ? -42.704 -28.731 -29.090  1.00 51.82  ? 383 GLY A CA    1 
ATOM   2982  C  C     . GLY A 1 383 ? -41.781 -29.001 -27.904  1.00 57.01  ? 383 GLY A C     1 
ATOM   2983  O  O     . GLY A 1 383 ? -41.419 -30.152 -27.674  1.00 55.42  ? 383 GLY A O     1 
ATOM   2984  N  N     . GLY A 1 384 ? -41.426 -27.962 -27.136  1.00 49.41  ? 384 GLY A N     1 
ATOM   2985  C  CA    . GLY A 1 384 ? -40.532 -28.140 -26.007  1.00 46.95  ? 384 GLY A CA    1 
ATOM   2986  C  C     . GLY A 1 384 ? -39.247 -27.358 -26.242  1.00 52.63  ? 384 GLY A C     1 
ATOM   2987  O  O     . GLY A 1 384 ? -38.611 -27.502 -27.280  1.00 53.58  ? 384 GLY A O     1 
ATOM   2988  N  N     . GLY A 1 385 ? -38.936 -26.449 -25.315  1.00 45.62  ? 385 GLY A N     1 
ATOM   2989  C  CA    . GLY A 1 385 ? -37.799 -25.566 -25.490  1.00 45.11  ? 385 GLY A CA    1 
ATOM   2990  C  C     . GLY A 1 385 ? -37.453 -24.894 -24.171  1.00 45.68  ? 385 GLY A C     1 
ATOM   2991  O  O     . GLY A 1 385 ? -38.118 -25.128 -23.167  1.00 44.63  ? 385 GLY A O     1 
ATOM   2992  N  N     . GLY A 1 386 ? -36.404 -24.074 -24.197  1.00 44.95  ? 386 GLY A N     1 
ATOM   2993  C  CA    . GLY A 1 386 ? -36.134 -23.151 -23.117  1.00 42.22  ? 386 GLY A CA    1 
ATOM   2994  C  C     . GLY A 1 386 ? -36.707 -21.771 -23.451  1.00 45.77  ? 386 GLY A C     1 
ATOM   2995  O  O     . GLY A 1 386 ? -37.291 -21.548 -24.515  1.00 39.89  ? 386 GLY A O     1 
ATOM   2996  N  N     . HIS A 1 387 ? -36.485 -20.830 -22.531  1.00 47.64  ? 387 HIS A N     1 
ATOM   2997  C  CA    . HIS A 1 387 ? -36.958 -19.471 -22.701  1.00 46.32  ? 387 HIS A CA    1 
ATOM   2998  C  C     . HIS A 1 387 ? -35.885 -18.524 -22.199  1.00 46.09  ? 387 HIS A C     1 
ATOM   2999  O  O     . HIS A 1 387 ? -34.986 -18.897 -21.460  1.00 50.49  ? 387 HIS A O     1 
ATOM   3000  C  CB    . HIS A 1 387 ? -38.286 -19.195 -21.990  1.00 44.92  ? 387 HIS A CB    1 
ATOM   3001  C  CG    . HIS A 1 387 ? -38.322 -19.223 -20.486  1.00 48.03  ? 387 HIS A CG    1 
ATOM   3002  N  ND1   . HIS A 1 387 ? -38.699 -18.062 -19.841  1.00 50.18  ? 387 HIS A ND1   1 
ATOM   3003  C  CD2   . HIS A 1 387 ? -38.181 -20.172 -19.514  1.00 56.07  ? 387 HIS A CD2   1 
ATOM   3004  C  CE1   . HIS A 1 387 ? -38.760 -18.254 -18.529  1.00 55.16  ? 387 HIS A CE1   1 
ATOM   3005  N  NE2   . HIS A 1 387 ? -38.438 -19.579 -18.233  1.00 61.20  ? 387 HIS A NE2   1 
ATOM   3006  N  N     . VAL A 1 388 ? -35.993 -17.308 -22.695  1.00 47.72  ? 388 VAL A N     1 
ATOM   3007  C  CA    . VAL A 1 388 ? -35.267 -16.193 -22.156  1.00 45.95  ? 388 VAL A CA    1 
ATOM   3008  C  C     . VAL A 1 388 ? -36.265 -15.046 -22.200  1.00 43.69  ? 388 VAL A C     1 
ATOM   3009  O  O     . VAL A 1 388 ? -37.207 -15.070 -23.006  1.00 42.90  ? 388 VAL A O     1 
ATOM   3010  C  CB    . VAL A 1 388 ? -33.981 -15.974 -22.973  1.00 49.55  ? 388 VAL A CB    1 
ATOM   3011  C  CG1   . VAL A 1 388 ? -34.254 -15.198 -24.254  1.00 45.11  ? 388 VAL A CG1   1 
ATOM   3012  C  CG2   . VAL A 1 388 ? -32.882 -15.330 -22.139  1.00 53.48  ? 388 VAL A CG2   1 
ATOM   3013  N  N     . GLY A 1 389 ? -36.080 -14.122 -21.263  1.00 35.81  ? 389 GLY A N     1 
ATOM   3014  C  CA    . GLY A 1 389 ? -36.970 -13.003 -21.045  1.00 40.46  ? 389 GLY A CA    1 
ATOM   3015  C  C     . GLY A 1 389 ? -36.216 -11.677 -21.074  1.00 38.43  ? 389 GLY A C     1 
ATOM   3016  O  O     . GLY A 1 389 ? -35.058 -11.608 -20.714  1.00 39.56  ? 389 GLY A O     1 
ATOM   3017  N  N     . PHE A 1 390 ? -36.884 -10.640 -21.556  1.00 42.52  ? 390 PHE A N     1 
ATOM   3018  C  CA    . PHE A 1 390 ? -36.295 -9.323  -21.639  1.00 42.47  ? 390 PHE A CA    1 
ATOM   3019  C  C     . PHE A 1 390 ? -37.358 -8.354  -21.150  1.00 39.97  ? 390 PHE A C     1 
ATOM   3020  O  O     . PHE A 1 390 ? -38.427 -8.268  -21.756  1.00 42.02  ? 390 PHE A O     1 
ATOM   3021  C  CB    . PHE A 1 390 ? -35.826 -9.054  -23.070  1.00 45.70  ? 390 PHE A CB    1 
ATOM   3022  C  CG    . PHE A 1 390 ? -35.305 -7.660  -23.277  1.00 39.58  ? 390 PHE A CG    1 
ATOM   3023  C  CD1   . PHE A 1 390 ? -34.263 -7.185  -22.502  1.00 45.79  ? 390 PHE A CD1   1 
ATOM   3024  C  CD2   . PHE A 1 390 ? -35.860 -6.822  -24.225  1.00 42.07  ? 390 PHE A CD2   1 
ATOM   3025  C  CE1   . PHE A 1 390 ? -33.784 -5.897  -22.681  1.00 46.86  ? 390 PHE A CE1   1 
ATOM   3026  C  CE2   . PHE A 1 390 ? -35.372 -5.535  -24.405  1.00 38.34  ? 390 PHE A CE2   1 
ATOM   3027  C  CZ    . PHE A 1 390 ? -34.343 -5.079  -23.630  1.00 40.69  ? 390 PHE A CZ    1 
ATOM   3028  N  N     . SER A 1 391 ? -37.073 -7.696  -20.020  1.00 36.69  ? 391 SER A N     1 
ATOM   3029  C  CA    . SER A 1 391 ? -38.097 -7.023  -19.240  1.00 38.42  ? 391 SER A CA    1 
ATOM   3030  C  C     . SER A 1 391 ? -37.670 -5.596  -18.880  1.00 36.75  ? 391 SER A C     1 
ATOM   3031  O  O     . SER A 1 391 ? -37.704 -5.191  -17.728  1.00 36.94  ? 391 SER A O     1 
ATOM   3032  C  CB    . SER A 1 391 ? -38.434 -7.833  -18.025  1.00 36.94  ? 391 SER A CB    1 
ATOM   3033  O  OG    . SER A 1 391 ? -37.283 -8.131  -17.277  1.00 36.30  ? 391 SER A OG    1 
ATOM   3034  N  N     . PRO A 1 392 ? -37.286 -4.756  -19.853  1.00 39.16  ? 392 PRO A N     1 
ATOM   3035  C  CA    . PRO A 1 392 ? -36.866 -3.379  -19.552  1.00 40.82  ? 392 PRO A CA    1 
ATOM   3036  C  C     . PRO A 1 392 ? -37.969 -2.495  -18.972  1.00 40.96  ? 392 PRO A C     1 
ATOM   3037  O  O     . PRO A 1 392 ? -39.162 -2.732  -19.182  1.00 39.94  ? 392 PRO A O     1 
ATOM   3038  C  CB    . PRO A 1 392 ? -36.462 -2.829  -20.931  1.00 36.27  ? 392 PRO A CB    1 
ATOM   3039  C  CG    . PRO A 1 392 ? -37.342 -3.609  -21.874  1.00 35.88  ? 392 PRO A CG    1 
ATOM   3040  C  CD    . PRO A 1 392 ? -37.317 -5.019  -21.296  1.00 37.66  ? 392 PRO A CD    1 
ATOM   3041  N  N     . VAL A 1 393 ? -37.533 -1.436  -18.290  1.00 39.93  ? 393 VAL A N     1 
ATOM   3042  C  CA    . VAL A 1 393 ? -38.438 -0.488  -17.676  1.00 38.08  ? 393 VAL A CA    1 
ATOM   3043  C  C     . VAL A 1 393 ? -38.772 0.617   -18.675  1.00 35.55  ? 393 VAL A C     1 
ATOM   3044  O  O     . VAL A 1 393 ? -37.911 1.055   -19.425  1.00 39.95  ? 393 VAL A O     1 
ATOM   3045  C  CB    . VAL A 1 393 ? -37.781 0.089   -16.409  1.00 40.22  ? 393 VAL A CB    1 
ATOM   3046  C  CG1   . VAL A 1 393 ? -38.717 1.000   -15.659  1.00 38.36  ? 393 VAL A CG1   1 
ATOM   3047  C  CG2   . VAL A 1 393 ? -37.279 -1.011  -15.494  1.00 42.64  ? 393 VAL A CG2   1 
ATOM   3048  N  N     . SER A 1 394 ? -40.007 1.113   -18.623  1.00 37.28  ? 394 SER A N     1 
ATOM   3049  C  CA    . SER A 1 394 ? -40.446 2.223   -19.450  1.00 39.91  ? 394 SER A CA    1 
ATOM   3050  C  C     . SER A 1 394 ? -41.527 2.994   -18.706  1.00 40.31  ? 394 SER A C     1 
ATOM   3051  O  O     . SER A 1 394 ? -42.028 2.506   -17.704  1.00 33.58  ? 394 SER A O     1 
ATOM   3052  C  CB    . SER A 1 394 ? -40.962 1.727   -20.764  1.00 40.45  ? 394 SER A CB    1 
ATOM   3053  O  OG    . SER A 1 394 ? -42.009 0.809   -20.543  1.00 47.49  ? 394 SER A OG    1 
ATOM   3054  N  N     . PRO A 1 395 ? -41.843 4.247   -19.101  1.00 37.05  ? 395 PRO A N     1 
ATOM   3055  C  CA    . PRO A 1 395 ? -43.002 4.956   -18.548  1.00 37.35  ? 395 PRO A CA    1 
ATOM   3056  C  C     . PRO A 1 395 ? -44.331 4.265   -18.854  1.00 35.35  ? 395 PRO A C     1 
ATOM   3057  O  O     . PRO A 1 395 ? -44.498 3.679   -19.921  1.00 38.44  ? 395 PRO A O     1 
ATOM   3058  C  CB    . PRO A 1 395 ? -42.954 6.349   -19.230  1.00 35.23  ? 395 PRO A CB    1 
ATOM   3059  C  CG    . PRO A 1 395 ? -41.496 6.503   -19.663  1.00 35.77  ? 395 PRO A CG    1 
ATOM   3060  C  CD    . PRO A 1 395 ? -41.016 5.097   -19.985  1.00 35.92  ? 395 PRO A CD    1 
ATOM   3061  N  N     . ILE A 1 396 ? -45.314 4.375   -17.941  1.00 37.17  ? 396 ILE A N     1 
ATOM   3062  C  CA    . ILE A 1 396 ? -46.629 3.816   -18.212  1.00 36.21  ? 396 ILE A CA    1 
ATOM   3063  C  C     . ILE A 1 396 ? -47.338 4.753   -19.177  1.00 37.01  ? 396 ILE A C     1 
ATOM   3064  O  O     . ILE A 1 396 ? -48.138 5.591   -18.768  1.00 40.60  ? 396 ILE A O     1 
ATOM   3065  C  CB    . ILE A 1 396 ? -47.480 3.564   -16.952  1.00 39.08  ? 396 ILE A CB    1 
ATOM   3066  C  CG1   . ILE A 1 396 ? -46.710 2.804   -15.873  1.00 36.40  ? 396 ILE A CG1   1 
ATOM   3067  C  CG2   . ILE A 1 396 ? -48.798 2.851   -17.307  1.00 38.20  ? 396 ILE A CG2   1 
ATOM   3068  C  CD1   . ILE A 1 396 ? -47.377 2.873   -14.520  1.00 36.73  ? 396 ILE A CD1   1 
ATOM   3069  N  N     . THR A 1 397 ? -47.072 4.534   -20.464  1.00 34.15  ? 397 THR A N     1 
ATOM   3070  C  CA    . THR A 1 397 ? -47.641 5.346   -21.531  1.00 38.08  ? 397 THR A CA    1 
ATOM   3071  C  C     . THR A 1 397 ? -48.094 4.434   -22.666  1.00 35.13  ? 397 THR A C     1 
ATOM   3072  O  O     . THR A 1 397 ? -47.430 3.466   -22.998  1.00 40.03  ? 397 THR A O     1 
ATOM   3073  C  CB    . THR A 1 397 ? -46.582 6.404   -21.874  1.00 42.27  ? 397 THR A CB    1 
ATOM   3074  O  OG1   . THR A 1 397 ? -46.868 7.575   -21.099  1.00 43.94  ? 397 THR A OG1   1 
ATOM   3075  C  CG2   . THR A 1 397 ? -46.481 6.758   -23.321  1.00 44.77  ? 397 THR A CG2   1 
ATOM   3076  N  N     . GLY A 1 398 ? -49.250 4.744   -23.251  1.00 38.97  ? 398 GLY A N     1 
ATOM   3077  C  CA    . GLY A 1 398 ? -49.706 4.082   -24.454  1.00 40.81  ? 398 GLY A CA    1 
ATOM   3078  C  C     . GLY A 1 398 ? -48.645 4.059   -25.542  1.00 41.51  ? 398 GLY A C     1 
ATOM   3079  O  O     . GLY A 1 398 ? -48.415 3.017   -26.153  1.00 43.24  ? 398 GLY A O     1 
ATOM   3080  N  N     . LYS A 1 399 ? -48.013 5.216   -25.771  1.00 44.03  ? 399 LYS A N     1 
ATOM   3081  C  CA    . LYS A 1 399 ? -47.018 5.372   -26.819  1.00 40.80  ? 399 LYS A CA    1 
ATOM   3082  C  C     . LYS A 1 399 ? -45.851 4.437   -26.560  1.00 37.88  ? 399 LYS A C     1 
ATOM   3083  O  O     . LYS A 1 399 ? -45.317 3.845   -27.479  1.00 39.26  ? 399 LYS A O     1 
ATOM   3084  C  CB    . LYS A 1 399 ? -46.547 6.830   -26.924  1.00 48.20  ? 399 LYS A CB    1 
ATOM   3085  C  CG    . LYS A 1 399 ? -47.574 7.807   -27.496  1.00 58.32  ? 399 LYS A CG    1 
ATOM   3086  C  CD    . LYS A 1 399 ? -48.014 7.446   -28.918  1.00 66.25  ? 399 LYS A CD    1 
ATOM   3087  C  CE    . LYS A 1 399 ? -48.871 8.483   -29.609  1.00 70.12  ? 399 LYS A CE    1 
ATOM   3088  N  NZ    . LYS A 1 399 ? -49.305 7.990   -30.938  1.00 72.57  ? 399 LYS A NZ    1 
ATOM   3089  N  N     . ASP A 1 400 ? -45.425 4.333   -25.311  1.00 36.45  ? 400 ASP A N     1 
ATOM   3090  C  CA    . ASP A 1 400 ? -44.263 3.520   -25.008  1.00 39.66  ? 400 ASP A CA    1 
ATOM   3091  C  C     . ASP A 1 400 ? -44.677 2.059   -25.174  1.00 39.05  ? 400 ASP A C     1 
ATOM   3092  O  O     . ASP A 1 400 ? -43.913 1.263   -25.673  1.00 37.00  ? 400 ASP A O     1 
ATOM   3093  C  CB    . ASP A 1 400 ? -43.725 3.791   -23.600  1.00 41.29  ? 400 ASP A CB    1 
ATOM   3094  C  CG    . ASP A 1 400 ? -42.959 5.101   -23.458  1.00 42.04  ? 400 ASP A CG    1 
ATOM   3095  O  OD1   . ASP A 1 400 ? -41.852 5.179   -24.015  1.00 48.00  ? 400 ASP A OD1   1 
ATOM   3096  O  OD2   . ASP A 1 400 ? -43.460 6.017   -22.764  1.00 39.52  ? 400 ASP A OD2   1 
ATOM   3097  N  N     . ALA A 1 401 ? -45.890 1.728   -24.728  1.00 36.34  ? 401 ALA A N     1 
ATOM   3098  C  CA    . ALA A 1 401 ? -46.378 0.361   -24.767  1.00 36.09  ? 401 ALA A CA    1 
ATOM   3099  C  C     . ALA A 1 401 ? -46.406 -0.122  -26.217  1.00 39.99  ? 401 ALA A C     1 
ATOM   3100  O  O     . ALA A 1 401 ? -45.831 -1.171  -26.514  1.00 40.78  ? 401 ALA A O     1 
ATOM   3101  C  CB    . ALA A 1 401 ? -47.736 0.279   -24.107  1.00 34.53  ? 401 ALA A CB    1 
ATOM   3102  N  N     . ILE A 1 402 ? -46.992 0.668   -27.128  1.00 40.71  ? 402 ILE A N     1 
ATOM   3103  C  CA    . ILE A 1 402 ? -47.197 0.206   -28.501  1.00 41.23  ? 402 ILE A CA    1 
ATOM   3104  C  C     . ILE A 1 402 ? -45.903 0.284   -29.323  1.00 43.25  ? 402 ILE A C     1 
ATOM   3105  O  O     . ILE A 1 402 ? -45.638 -0.578  -30.174  1.00 43.35  ? 402 ILE A O     1 
ATOM   3106  C  CB    . ILE A 1 402 ? -48.391 0.917   -29.165  1.00 42.97  ? 402 ILE A CB    1 
ATOM   3107  C  CG1   . ILE A 1 402 ? -48.970 0.047   -30.298  1.00 44.88  ? 402 ILE A CG1   1 
ATOM   3108  C  CG2   . ILE A 1 402 ? -48.017 2.329   -29.602  1.00 41.17  ? 402 ILE A CG2   1 
ATOM   3109  C  CD1   . ILE A 1 402 ? -50.282 0.514   -30.840  1.00 54.14  ? 402 ILE A CD1   1 
ATOM   3110  N  N     . LYS A 1 403 ? -45.035 1.253   -29.019  1.00 40.33  ? 403 LYS A N     1 
ATOM   3111  C  CA    . LYS A 1 403 ? -43.730 1.276   -29.659  1.00 39.03  ? 403 LYS A CA    1 
ATOM   3112  C  C     . LYS A 1 403 ? -42.937 0.000   -29.364  1.00 40.94  ? 403 LYS A C     1 
ATOM   3113  O  O     . LYS A 1 403 ? -42.316 -0.574  -30.255  1.00 36.68  ? 403 LYS A O     1 
ATOM   3114  C  CB    . LYS A 1 403 ? -42.909 2.484   -29.209  1.00 42.90  ? 403 LYS A CB    1 
ATOM   3115  C  CG    . LYS A 1 403 ? -41.608 2.636   -29.987  1.00 49.06  ? 403 LYS A CG    1 
ATOM   3116  C  CD    . LYS A 1 403 ? -40.523 3.278   -29.199  1.00 53.94  ? 403 LYS A CD    1 
ATOM   3117  C  CE    . LYS A 1 403 ? -40.767 4.741   -28.919  1.00 57.02  ? 403 LYS A CE    1 
ATOM   3118  N  NZ    . LYS A 1 403 ? -39.753 5.253   -27.964  1.00 67.64  ? 403 LYS A NZ    1 
ATOM   3119  N  N     . GLN A 1 404 ? -42.893 -0.417  -28.095  1.00 38.83  ? 404 GLN A N     1 
ATOM   3120  C  CA    . GLN A 1 404 ? -42.182 -1.642  -27.745  1.00 42.20  ? 404 GLN A CA    1 
ATOM   3121  C  C     . GLN A 1 404 ? -42.839 -2.890  -28.363  1.00 37.93  ? 404 GLN A C     1 
ATOM   3122  O  O     . GLN A 1 404 ? -42.134 -3.756  -28.873  1.00 35.36  ? 404 GLN A O     1 
ATOM   3123  C  CB    . GLN A 1 404 ? -42.073 -1.755  -26.225  1.00 42.68  ? 404 GLN A CB    1 
ATOM   3124  C  CG    . GLN A 1 404 ? -41.107 -0.738  -25.655  1.00 42.49  ? 404 GLN A CG    1 
ATOM   3125  C  CD    . GLN A 1 404 ? -41.109 -0.724  -24.155  1.00 39.78  ? 404 GLN A CD    1 
ATOM   3126  O  OE1   . GLN A 1 404 ? -40.241 -1.320  -23.523  1.00 43.88  ? 404 GLN A OE1   1 
ATOM   3127  N  NE2   . GLN A 1 404 ? -42.088 -0.042  -23.584  1.00 40.81  ? 404 GLN A NE2   1 
ATOM   3128  N  N     . TYR A 1 405 ? -44.164 -3.020  -28.270  1.00 33.46  ? 405 TYR A N     1 
ATOM   3129  C  CA    . TYR A 1 405 ? -44.885 -4.057  -28.997  1.00 37.11  ? 405 TYR A CA    1 
ATOM   3130  C  C     . TYR A 1 405 ? -44.433 -4.111  -30.469  1.00 38.84  ? 405 TYR A C     1 
ATOM   3131  O  O     . TYR A 1 405 ? -44.060 -5.174  -30.958  1.00 34.92  ? 405 TYR A O     1 
ATOM   3132  C  CB    . TYR A 1 405 ? -46.410 -3.906  -28.892  1.00 33.30  ? 405 TYR A CB    1 
ATOM   3133  C  CG    . TYR A 1 405 ? -47.170 -4.832  -29.813  1.00 37.14  ? 405 TYR A CG    1 
ATOM   3134  C  CD1   . TYR A 1 405 ? -47.092 -6.210  -29.652  1.00 42.89  ? 405 TYR A CD1   1 
ATOM   3135  C  CD2   . TYR A 1 405 ? -47.889 -4.359  -30.899  1.00 41.85  ? 405 TYR A CD2   1 
ATOM   3136  C  CE1   . TYR A 1 405 ? -47.759 -7.088  -30.498  1.00 43.12  ? 405 TYR A CE1   1 
ATOM   3137  C  CE2   . TYR A 1 405 ? -48.535 -5.222  -31.777  1.00 41.52  ? 405 TYR A CE2   1 
ATOM   3138  C  CZ    . TYR A 1 405 ? -48.487 -6.592  -31.560  1.00 47.78  ? 405 TYR A CZ    1 
ATOM   3139  O  OH    . TYR A 1 405 ? -49.124 -7.491  -32.374  1.00 56.78  ? 405 TYR A OH    1 
ATOM   3140  N  N     . ASN A 1 406 ? -44.412 -2.963  -31.161  1.00 45.31  ? 406 ASN A N     1 
ATOM   3141  C  CA    . ASN A 1 406 ? -44.124 -2.919  -32.597  1.00 44.25  ? 406 ASN A CA    1 
ATOM   3142  C  C     . ASN A 1 406 ? -42.676 -3.304  -32.895  1.00 48.80  ? 406 ASN A C     1 
ATOM   3143  O  O     . ASN A 1 406 ? -42.423 -4.047  -33.847  1.00 45.11  ? 406 ASN A O     1 
ATOM   3144  C  CB    . ASN A 1 406 ? -44.477 -1.552  -33.198  1.00 43.44  ? 406 ASN A CB    1 
ATOM   3145  C  CG    . ASN A 1 406 ? -45.977 -1.350  -33.349  1.00 46.05  ? 406 ASN A CG    1 
ATOM   3146  O  OD1   . ASN A 1 406 ? -46.758 -2.296  -33.318  1.00 51.04  ? 406 ASN A OD1   1 
ATOM   3147  N  ND2   . ASN A 1 406 ? -46.405 -0.117  -33.530  1.00 51.31  ? 406 ASN A ND2   1 
ATOM   3148  N  N     . MET A 1 407 ? -41.748 -2.792  -32.074  1.00 42.45  ? 407 MET A N     1 
ATOM   3149  C  CA    . MET A 1 407 ? -40.323 -3.042  -32.208  1.00 44.49  ? 407 MET A CA    1 
ATOM   3150  C  C     . MET A 1 407 ? -40.023 -4.521  -31.984  1.00 42.43  ? 407 MET A C     1 
ATOM   3151  O  O     . MET A 1 407 ? -39.165 -5.096  -32.641  1.00 37.77  ? 407 MET A O     1 
ATOM   3152  C  CB    . MET A 1 407 ? -39.519 -2.303  -31.131  1.00 46.93  ? 407 MET A CB    1 
ATOM   3153  C  CG    . MET A 1 407 ? -39.375 -0.825  -31.349  1.00 54.01  ? 407 MET A CG    1 
ATOM   3154  S  SD    . MET A 1 407 ? -38.629 -0.097  -29.870  1.00 44.74  ? 407 MET A SD    1 
ATOM   3155  C  CE    . MET A 1 407 ? -36.892 -0.432  -30.155  1.00 43.02  ? 407 MET A CE    1 
ATOM   3156  N  N     . VAL A 1 408 ? -40.632 -5.087  -30.949  1.00 38.51  ? 408 VAL A N     1 
ATOM   3157  C  CA    . VAL A 1 408 ? -40.257 -6.417  -30.528  1.00 41.83  ? 408 VAL A CA    1 
ATOM   3158  C  C     . VAL A 1 408 ? -40.929 -7.441  -31.431  1.00 38.02  ? 408 VAL A C     1 
ATOM   3159  O  O     . VAL A 1 408 ? -40.215 -8.305  -31.939  1.00 42.29  ? 408 VAL A O     1 
ATOM   3160  C  CB    . VAL A 1 408 ? -40.545 -6.661  -29.040  1.00 42.13  ? 408 VAL A CB    1 
ATOM   3161  C  CG1   . VAL A 1 408 ? -40.423 -8.128  -28.695  1.00 40.04  ? 408 VAL A CG1   1 
ATOM   3162  C  CG2   . VAL A 1 408 ? -39.617 -5.815  -28.177  1.00 46.77  ? 408 VAL A CG2   1 
ATOM   3163  N  N     . SER A 1 409 ? -42.261 -7.328  -31.631  1.00 39.99  ? 409 SER A N     1 
ATOM   3164  C  CA    . SER A 1 409 ? -42.993 -8.349  -32.371  1.00 44.38  ? 409 SER A CA    1 
ATOM   3165  C  C     . SER A 1 409 ? -42.430 -8.521  -33.791  1.00 45.71  ? 409 SER A C     1 
ATOM   3166  O  O     . SER A 1 409 ? -42.204 -9.655  -34.216  1.00 44.79  ? 409 SER A O     1 
ATOM   3167  C  CB    . SER A 1 409 ? -44.490 -8.140  -32.362  1.00 46.59  ? 409 SER A CB    1 
ATOM   3168  O  OG    . SER A 1 409 ? -44.850 -6.882  -32.901  1.00 49.34  ? 409 SER A OG    1 
ATOM   3169  N  N     . SER A 1 410 ? -42.124 -7.411  -34.479  1.00 39.47  ? 410 SER A N     1 
ATOM   3170  C  CA    . SER A 1 410 ? -41.580 -7.434  -35.828  1.00 43.19  ? 410 SER A CA    1 
ATOM   3171  C  C     . SER A 1 410 ? -40.267 -8.200  -35.890  1.00 44.02  ? 410 SER A C     1 
ATOM   3172  O  O     . SER A 1 410 ? -40.064 -9.007  -36.784  1.00 50.87  ? 410 SER A O     1 
ATOM   3173  C  CB    . SER A 1 410 ? -41.368 -6.054  -36.326  1.00 45.94  ? 410 SER A CB    1 
ATOM   3174  O  OG    . SER A 1 410 ? -42.606 -5.381  -36.338  1.00 61.12  ? 410 SER A OG    1 
ATOM   3175  N  N     . ARG A 1 411 ? -39.365 -7.931  -34.947  1.00 42.27  ? 411 ARG A N     1 
ATOM   3176  C  CA    . ARG A 1 411 ? -38.091 -8.626  -34.935  1.00 44.96  ? 411 ARG A CA    1 
ATOM   3177  C  C     . ARG A 1 411 ? -38.305 -10.112 -34.676  1.00 42.01  ? 411 ARG A C     1 
ATOM   3178  O  O     . ARG A 1 411 ? -37.671 -10.942 -35.312  1.00 39.86  ? 411 ARG A O     1 
ATOM   3179  C  CB    . ARG A 1 411 ? -37.160 -8.116  -33.835  1.00 49.55  ? 411 ARG A CB    1 
ATOM   3180  C  CG    . ARG A 1 411 ? -36.723 -6.665  -33.984  1.00 55.57  ? 411 ARG A CG    1 
ATOM   3181  C  CD    . ARG A 1 411 ? -35.862 -6.550  -35.193  1.00 51.96  ? 411 ARG A CD    1 
ATOM   3182  N  NE    . ARG A 1 411 ? -34.885 -5.488  -35.226  1.00 46.87  ? 411 ARG A NE    1 
ATOM   3183  C  CZ    . ARG A 1 411 ? -34.071 -5.361  -36.263  1.00 48.85  ? 411 ARG A CZ    1 
ATOM   3184  N  NH1   . ARG A 1 411 ? -34.140 -6.257  -37.224  1.00 47.55  ? 411 ARG A NH1   1 
ATOM   3185  N  NH2   . ARG A 1 411 ? -33.188 -4.388  -36.350  1.00 49.68  ? 411 ARG A NH2   1 
ATOM   3186  N  N     . VAL A 1 412 ? -39.084 -10.410 -33.636  1.00 39.89  ? 412 VAL A N     1 
ATOM   3187  C  CA    . VAL A 1 412 ? -39.165 -11.751 -33.090  1.00 41.94  ? 412 VAL A CA    1 
ATOM   3188  C  C     . VAL A 1 412 ? -39.767 -12.637 -34.178  1.00 38.87  ? 412 VAL A C     1 
ATOM   3189  O  O     . VAL A 1 412 ? -39.265 -13.720 -34.450  1.00 38.08  ? 412 VAL A O     1 
ATOM   3190  C  CB    . VAL A 1 412 ? -39.946 -11.741 -31.751  1.00 42.59  ? 412 VAL A CB    1 
ATOM   3191  C  CG1   . VAL A 1 412 ? -40.692 -13.018 -31.447  1.00 46.60  ? 412 VAL A CG1   1 
ATOM   3192  C  CG2   . VAL A 1 412 ? -39.039 -11.408 -30.589  1.00 40.48  ? 412 VAL A CG2   1 
ATOM   3193  N  N     . ARG A 1 413 ? -40.771 -12.100 -34.867  1.00 38.53  ? 413 ARG A N     1 
ATOM   3194  C  CA    . ARG A 1 413 ? -41.475 -12.841 -35.893  1.00 43.44  ? 413 ARG A CA    1 
ATOM   3195  C  C     . ARG A 1 413 ? -40.611 -12.974 -37.141  1.00 47.74  ? 413 ARG A C     1 
ATOM   3196  O  O     . ARG A 1 413 ? -40.631 -14.031 -37.763  1.00 43.07  ? 413 ARG A O     1 
ATOM   3197  C  CB    . ARG A 1 413 ? -42.829 -12.205 -36.194  1.00 41.29  ? 413 ARG A CB    1 
ATOM   3198  C  CG    . ARG A 1 413 ? -43.846 -12.490 -35.100  1.00 39.53  ? 413 ARG A CG    1 
ATOM   3199  C  CD    . ARG A 1 413 ? -45.150 -11.746 -35.291  1.00 39.48  ? 413 ARG A CD    1 
ATOM   3200  N  NE    . ARG A 1 413 ? -45.672 -11.921 -36.629  1.00 43.65  ? 413 ARG A NE    1 
ATOM   3201  C  CZ    . ARG A 1 413 ? -46.566 -12.835 -36.998  1.00 50.95  ? 413 ARG A CZ    1 
ATOM   3202  N  NH1   . ARG A 1 413 ? -46.933 -13.833 -36.202  1.00 48.48  ? 413 ARG A NH1   1 
ATOM   3203  N  NH2   . ARG A 1 413 ? -47.066 -12.767 -38.210  1.00 46.91  ? 413 ARG A NH2   1 
ATOM   3204  N  N     . GLU A 1 414 ? -39.806 -11.949 -37.447  1.00 45.77  ? 414 GLU A N     1 
ATOM   3205  C  CA    . GLU A 1 414 ? -38.868 -12.043 -38.552  1.00 46.55  ? 414 GLU A CA    1 
ATOM   3206  C  C     . GLU A 1 414 ? -37.902 -13.198 -38.330  1.00 44.07  ? 414 GLU A C     1 
ATOM   3207  O  O     . GLU A 1 414 ? -37.460 -13.814 -39.286  1.00 42.71  ? 414 GLU A O     1 
ATOM   3208  C  CB    . GLU A 1 414 ? -38.072 -10.758 -38.771  1.00 45.41  ? 414 GLU A CB    1 
ATOM   3209  C  CG    . GLU A 1 414 ? -37.010 -10.962 -39.846  1.00 52.60  ? 414 GLU A CG    1 
ATOM   3210  C  CD    . GLU A 1 414 ? -36.328 -9.749  -40.455  1.00 53.27  ? 414 GLU A CD    1 
ATOM   3211  O  OE1   . GLU A 1 414 ? -36.876 -8.622  -40.400  1.00 56.57  ? 414 GLU A OE1   1 
ATOM   3212  O  OE2   . GLU A 1 414 ? -35.226 -9.944  -40.957  1.00 56.58  ? 414 GLU A OE2   1 
ATOM   3213  N  N     . TYR A 1 415 ? -37.585 -13.497 -37.069  1.00 44.58  ? 415 TYR A N     1 
ATOM   3214  C  CA    . TYR A 1 415 ? -36.583 -14.509 -36.754  1.00 43.52  ? 415 TYR A CA    1 
ATOM   3215  C  C     . TYR A 1 415 ? -37.219 -15.900 -36.742  1.00 41.56  ? 415 TYR A C     1 
ATOM   3216  O  O     . TYR A 1 415 ? -36.533 -16.892 -36.505  1.00 48.57  ? 415 TYR A O     1 
ATOM   3217  C  CB    . TYR A 1 415 ? -35.888 -14.197 -35.413  1.00 40.67  ? 415 TYR A CB    1 
ATOM   3218  C  CG    . TYR A 1 415 ? -34.662 -13.321 -35.529  1.00 37.95  ? 415 TYR A CG    1 
ATOM   3219  C  CD1   . TYR A 1 415 ? -34.765 -11.984 -35.880  1.00 41.65  ? 415 TYR A CD1   1 
ATOM   3220  C  CD2   . TYR A 1 415 ? -33.395 -13.829 -35.325  1.00 41.99  ? 415 TYR A CD2   1 
ATOM   3221  C  CE1   . TYR A 1 415 ? -33.649 -11.182 -36.035  1.00 37.29  ? 415 TYR A CE1   1 
ATOM   3222  C  CE2   . TYR A 1 415 ? -32.268 -13.034 -35.461  1.00 43.89  ? 415 TYR A CE2   1 
ATOM   3223  C  CZ    . TYR A 1 415 ? -32.391 -11.712 -35.839  1.00 41.77  ? 415 TYR A CZ    1 
ATOM   3224  O  OH    . TYR A 1 415 ? -31.262 -10.930 -35.997  1.00 46.83  ? 415 TYR A OH    1 
ATOM   3225  N  N     . GLY A 1 416 ? -38.524 -15.972 -36.992  1.00 41.07  ? 416 GLY A N     1 
ATOM   3226  C  CA    . GLY A 1 416 ? -39.222 -17.247 -37.003  1.00 48.02  ? 416 GLY A CA    1 
ATOM   3227  C  C     . GLY A 1 416 ? -39.877 -17.620 -35.670  1.00 49.73  ? 416 GLY A C     1 
ATOM   3228  O  O     . GLY A 1 416 ? -40.525 -18.652 -35.609  1.00 52.82  ? 416 GLY A O     1 
ATOM   3229  N  N     . PHE A 1 417 ? -39.725 -16.816 -34.603  1.00 46.68  ? 417 PHE A N     1 
ATOM   3230  C  CA    . PHE A 1 417 ? -40.395 -17.136 -33.351  1.00 39.29  ? 417 PHE A CA    1 
ATOM   3231  C  C     . PHE A 1 417 ? -41.749 -16.454 -33.325  1.00 37.91  ? 417 PHE A C     1 
ATOM   3232  O  O     . PHE A 1 417 ? -41.910 -15.399 -33.916  1.00 44.46  ? 417 PHE A O     1 
ATOM   3233  C  CB    . PHE A 1 417 ? -39.583 -16.676 -32.147  1.00 40.44  ? 417 PHE A CB    1 
ATOM   3234  C  CG    . PHE A 1 417 ? -38.192 -17.230 -32.094  1.00 40.06  ? 417 PHE A CG    1 
ATOM   3235  C  CD1   . PHE A 1 417 ? -37.967 -18.527 -31.667  1.00 39.24  ? 417 PHE A CD1   1 
ATOM   3236  C  CD2   . PHE A 1 417 ? -37.117 -16.466 -32.500  1.00 39.21  ? 417 PHE A CD2   1 
ATOM   3237  C  CE1   . PHE A 1 417 ? -36.683 -19.038 -31.630  1.00 41.41  ? 417 PHE A CE1   1 
ATOM   3238  C  CE2   . PHE A 1 417 ? -35.828 -16.977 -32.447  1.00 42.92  ? 417 PHE A CE2   1 
ATOM   3239  C  CZ    . PHE A 1 417 ? -35.615 -18.253 -32.002  1.00 41.35  ? 417 PHE A CZ    1 
ATOM   3240  N  N     . ASP A 1 418 ? -42.709 -17.033 -32.599  1.00 43.49  ? 418 ASP A N     1 
ATOM   3241  C  CA    . ASP A 1 418 ? -43.936 -16.323 -32.255  1.00 44.62  ? 418 ASP A CA    1 
ATOM   3242  C  C     . ASP A 1 418 ? -43.647 -15.236 -31.217  1.00 42.73  ? 418 ASP A C     1 
ATOM   3243  O  O     . ASP A 1 418 ? -42.863 -15.424 -30.293  1.00 39.46  ? 418 ASP A O     1 
ATOM   3244  C  CB    . ASP A 1 418 ? -45.025 -17.256 -31.729  1.00 42.01  ? 418 ASP A CB    1 
ATOM   3245  C  CG    . ASP A 1 418 ? -45.838 -17.854 -32.856  1.00 38.67  ? 418 ASP A CG    1 
ATOM   3246  O  OD1   . ASP A 1 418 ? -46.505 -17.069 -33.558  1.00 39.67  ? 418 ASP A OD1   1 
ATOM   3247  O  OD2   . ASP A 1 418 ? -45.753 -19.094 -33.041  1.00 37.98  ? 418 ASP A OD2   1 
ATOM   3248  N  N     . TYR A 1 419 ? -44.318 -14.099 -31.383  1.00 42.66  ? 419 TYR A N     1 
ATOM   3249  C  CA    . TYR A 1 419 ? -44.262 -13.052 -30.383  1.00 39.63  ? 419 TYR A CA    1 
ATOM   3250  C  C     . TYR A 1 419 ? -45.052 -13.484 -29.148  1.00 40.35  ? 419 TYR A C     1 
ATOM   3251  O  O     . TYR A 1 419 ? -46.255 -13.752 -29.202  1.00 39.52  ? 419 TYR A O     1 
ATOM   3252  C  CB    . TYR A 1 419 ? -44.820 -11.732 -30.905  1.00 39.46  ? 419 TYR A CB    1 
ATOM   3253  C  CG    . TYR A 1 419 ? -45.006 -10.692 -29.829  1.00 42.18  ? 419 TYR A CG    1 
ATOM   3254  C  CD1   . TYR A 1 419 ? -43.924 -10.024 -29.257  1.00 44.69  ? 419 TYR A CD1   1 
ATOM   3255  C  CD2   . TYR A 1 419 ? -46.271 -10.353 -29.395  1.00 40.78  ? 419 TYR A CD2   1 
ATOM   3256  C  CE1   . TYR A 1 419 ? -44.110 -9.044  -28.289  1.00 41.51  ? 419 TYR A CE1   1 
ATOM   3257  C  CE2   . TYR A 1 419 ? -46.475 -9.393  -28.416  1.00 44.66  ? 419 TYR A CE2   1 
ATOM   3258  C  CZ    . TYR A 1 419 ? -45.391 -8.736  -27.859  1.00 44.11  ? 419 TYR A CZ    1 
ATOM   3259  O  OH    . TYR A 1 419 ? -45.641 -7.804  -26.880  1.00 49.27  ? 419 TYR A OH    1 
ATOM   3260  N  N     . MET A 1 420 ? -44.336 -13.516 -28.029  1.00 34.54  ? 420 MET A N     1 
ATOM   3261  C  CA    . MET A 1 420 ? -44.903 -13.731 -26.722  1.00 38.74  ? 420 MET A CA    1 
ATOM   3262  C  C     . MET A 1 420 ? -44.450 -12.568 -25.848  1.00 43.69  ? 420 MET A C     1 
ATOM   3263  O  O     . MET A 1 420 ? -43.261 -12.418 -25.540  1.00 46.15  ? 420 MET A O     1 
ATOM   3264  C  CB    . MET A 1 420 ? -44.390 -15.044 -26.141  1.00 38.61  ? 420 MET A CB    1 
ATOM   3265  C  CG    . MET A 1 420 ? -45.034 -16.260 -26.740  1.00 41.57  ? 420 MET A CG    1 
ATOM   3266  S  SD    . MET A 1 420 ? -44.169 -17.640 -26.032  1.00 48.38  ? 420 MET A SD    1 
ATOM   3267  C  CE    . MET A 1 420 ? -44.883 -18.998 -26.952  1.00 48.08  ? 420 MET A CE    1 
ATOM   3268  N  N     . GLY A 1 421 ? -45.405 -11.722 -25.491  1.00 42.91  ? 421 GLY A N     1 
ATOM   3269  C  CA    . GLY A 1 421 ? -45.078 -10.522 -24.751  1.00 45.14  ? 421 GLY A CA    1 
ATOM   3270  C  C     . GLY A 1 421 ? -46.132 -10.249 -23.701  1.00 48.38  ? 421 GLY A C     1 
ATOM   3271  O  O     . GLY A 1 421 ? -47.258 -10.774 -23.751  1.00 49.58  ? 421 GLY A O     1 
ATOM   3272  N  N     . LEU A 1 422 ? -45.737 -9.433  -22.735  1.00 43.01  ? 422 LEU A N     1 
ATOM   3273  C  CA    . LEU A 1 422 ? -46.730 -8.870  -21.839  1.00 41.66  ? 422 LEU A CA    1 
ATOM   3274  C  C     . LEU A 1 422 ? -46.291 -7.462  -21.441  1.00 43.90  ? 422 LEU A C     1 
ATOM   3275  O  O     . LEU A 1 422 ? -45.107 -7.120  -21.495  1.00 41.78  ? 422 LEU A O     1 
ATOM   3276  C  CB    . LEU A 1 422 ? -46.877 -9.813  -20.648  1.00 43.71  ? 422 LEU A CB    1 
ATOM   3277  C  CG    . LEU A 1 422 ? -45.643 -9.964  -19.769  1.00 51.28  ? 422 LEU A CG    1 
ATOM   3278  C  CD1   . LEU A 1 422 ? -45.605 -8.885  -18.703  1.00 55.07  ? 422 LEU A CD1   1 
ATOM   3279  C  CD2   . LEU A 1 422 ? -45.623 -11.322 -19.111  1.00 56.55  ? 422 LEU A CD2   1 
ATOM   3280  N  N     . LEU A 1 423 ? -47.282 -6.655  -21.079  1.00 43.51  ? 423 LEU A N     1 
ATOM   3281  C  CA    . LEU A 1 423 ? -47.063 -5.391  -20.408  1.00 42.78  ? 423 LEU A CA    1 
ATOM   3282  C  C     . LEU A 1 423 ? -47.424 -5.529  -18.930  1.00 43.70  ? 423 LEU A C     1 
ATOM   3283  O  O     . LEU A 1 423 ? -48.579 -5.801  -18.588  1.00 43.76  ? 423 LEU A O     1 
ATOM   3284  C  CB    . LEU A 1 423 ? -47.857 -4.339  -21.186  1.00 43.16  ? 423 LEU A CB    1 
ATOM   3285  C  CG    . LEU A 1 423 ? -47.188 -4.079  -22.541  1.00 50.93  ? 423 LEU A CG    1 
ATOM   3286  C  CD1   . LEU A 1 423 ? -48.111 -4.363  -23.705  1.00 57.80  ? 423 LEU A CD1   1 
ATOM   3287  C  CD2   . LEU A 1 423 ? -46.575 -2.694  -22.618  1.00 49.42  ? 423 LEU A CD2   1 
ATOM   3288  N  N     . ALA A 1 424 ? -46.374 -5.427  -18.091  1.00 40.14  ? 424 ALA A N     1 
ATOM   3289  C  CA    . ALA A 1 424 ? -46.442 -5.521  -16.637  1.00 42.27  ? 424 ALA A CA    1 
ATOM   3290  C  C     . ALA A 1 424 ? -46.310 -4.129  -16.008  1.00 44.88  ? 424 ALA A C     1 
ATOM   3291  O  O     . ALA A 1 424 ? -45.428 -3.360  -16.387  1.00 45.26  ? 424 ALA A O     1 
ATOM   3292  C  CB    . ALA A 1 424 ? -45.326 -6.406  -16.136  1.00 40.13  ? 424 ALA A CB    1 
ATOM   3293  N  N     . ILE A 1 425 ? -47.175 -3.808  -15.045  1.00 41.90  ? 425 ILE A N     1 
ATOM   3294  C  CA    . ILE A 1 425 ? -47.025 -2.583  -14.270  1.00 43.22  ? 425 ILE A CA    1 
ATOM   3295  C  C     . ILE A 1 425 ? -46.913 -2.932  -12.786  1.00 40.91  ? 425 ILE A C     1 
ATOM   3296  O  O     . ILE A 1 425 ? -47.833 -3.541  -12.253  1.00 39.41  ? 425 ILE A O     1 
ATOM   3297  C  CB    . ILE A 1 425 ? -48.190 -1.616  -14.541  1.00 46.92  ? 425 ILE A CB    1 
ATOM   3298  C  CG1   . ILE A 1 425 ? -48.363 -1.333  -16.036  1.00 47.51  ? 425 ILE A CG1   1 
ATOM   3299  C  CG2   . ILE A 1 425 ? -48.000 -0.334  -13.747  1.00 45.85  ? 425 ILE A CG2   1 
ATOM   3300  C  CD1   . ILE A 1 425 ? -49.627 -0.562  -16.370  1.00 54.35  ? 425 ILE A CD1   1 
ATOM   3301  N  N     . GLY A 1 426 ? -45.762 -2.588  -12.170  1.00 37.92  ? 426 GLY A N     1 
ATOM   3302  C  CA    . GLY A 1 426 ? -45.521 -2.750  -10.741  1.00 38.12  ? 426 GLY A CA    1 
ATOM   3303  C  C     . GLY A 1 426 ? -46.329 -1.737  -9.931   1.00 43.35  ? 426 GLY A C     1 
ATOM   3304  O  O     . GLY A 1 426 ? -47.246 -2.128  -9.207   1.00 48.13  ? 426 GLY A O     1 
ATOM   3305  N  N     . TRP A 1 427 ? -45.980 -0.445  -10.080  1.00 40.30  ? 427 TRP A N     1 
ATOM   3306  C  CA    . TRP A 1 427 ? -46.686 0.654   -9.432   1.00 43.08  ? 427 TRP A CA    1 
ATOM   3307  C  C     . TRP A 1 427 ? -46.647 1.881   -10.345  1.00 40.15  ? 427 TRP A C     1 
ATOM   3308  O  O     . TRP A 1 427 ? -47.672 2.340   -10.821  1.00 44.65  ? 427 TRP A O     1 
ATOM   3309  C  CB    . TRP A 1 427 ? -46.092 0.954   -8.039   1.00 40.40  ? 427 TRP A CB    1 
ATOM   3310  C  CG    . TRP A 1 427 ? -46.886 1.930   -7.219   1.00 42.59  ? 427 TRP A CG    1 
ATOM   3311  C  CD1   . TRP A 1 427 ? -48.085 2.497   -7.550   1.00 43.97  ? 427 TRP A CD1   1 
ATOM   3312  C  CD2   . TRP A 1 427 ? -46.587 2.407   -5.891   1.00 39.52  ? 427 TRP A CD2   1 
ATOM   3313  N  NE1   . TRP A 1 427 ? -48.548 3.278   -6.521   1.00 43.76  ? 427 TRP A NE1   1 
ATOM   3314  C  CE2   . TRP A 1 427 ? -47.639 3.273   -5.505   1.00 40.69  ? 427 TRP A CE2   1 
ATOM   3315  C  CE3   . TRP A 1 427 ? -45.510 2.240   -5.013   1.00 37.61  ? 427 TRP A CE3   1 
ATOM   3316  C  CZ2   . TRP A 1 427 ? -47.649 3.952   -4.278   1.00 44.06  ? 427 TRP A CZ2   1 
ATOM   3317  C  CZ3   . TRP A 1 427 ? -45.506 2.921   -3.813   1.00 37.77  ? 427 TRP A CZ3   1 
ATOM   3318  C  CH2   . TRP A 1 427 ? -46.580 3.737   -3.431   1.00 43.12  ? 427 TRP A CH2   1 
ATOM   3319  N  N     . ARG A 1 428 ? -45.453 2.420   -10.590  1.00 37.23  ? 428 ARG A N     1 
ATOM   3320  C  CA    . ARG A 1 428 ? -45.315 3.517   -11.540  1.00 38.97  ? 428 ARG A CA    1 
ATOM   3321  C  C     . ARG A 1 428 ? -44.494 3.068   -12.749  1.00 38.76  ? 428 ARG A C     1 
ATOM   3322  O  O     . ARG A 1 428 ? -44.158 3.885   -13.610  1.00 36.05  ? 428 ARG A O     1 
ATOM   3323  C  CB    . ARG A 1 428 ? -44.629 4.692   -10.835  1.00 39.33  ? 428 ARG A CB    1 
ATOM   3324  C  CG    . ARG A 1 428 ? -45.516 5.458   -9.867   1.00 39.24  ? 428 ARG A CG    1 
ATOM   3325  C  CD    . ARG A 1 428 ? -44.677 6.443   -9.092   1.00 35.48  ? 428 ARG A CD    1 
ATOM   3326  N  NE    . ARG A 1 428 ? -45.520 7.349   -8.334   1.00 36.65  ? 428 ARG A NE    1 
ATOM   3327  C  CZ    . ARG A 1 428 ? -46.140 7.058   -7.201   1.00 34.39  ? 428 ARG A CZ    1 
ATOM   3328  N  NH1   . ARG A 1 428 ? -45.999 5.880   -6.629   1.00 37.10  ? 428 ARG A NH1   1 
ATOM   3329  N  NH2   . ARG A 1 428 ? -46.878 7.980   -6.614   1.00 38.75  ? 428 ARG A NH2   1 
ATOM   3330  N  N     . ASP A 1 429 ? -44.145 1.773   -12.786  1.00 36.83  ? 429 ASP A N     1 
ATOM   3331  C  CA    . ASP A 1 429 ? -43.202 1.243   -13.761  1.00 37.16  ? 429 ASP A CA    1 
ATOM   3332  C  C     . ASP A 1 429 ? -43.894 0.284   -14.731  1.00 41.25  ? 429 ASP A C     1 
ATOM   3333  O  O     . ASP A 1 429 ? -44.499 -0.697  -14.318  1.00 38.37  ? 429 ASP A O     1 
ATOM   3334  C  CB    . ASP A 1 429 ? -42.064 0.463   -13.089  1.00 38.81  ? 429 ASP A CB    1 
ATOM   3335  C  CG    . ASP A 1 429 ? -42.521 -0.634  -12.131  1.00 40.36  ? 429 ASP A CG    1 
ATOM   3336  O  OD1   . ASP A 1 429 ? -43.423 -0.363  -11.311  1.00 39.40  ? 429 ASP A OD1   1 
ATOM   3337  O  OD2   . ASP A 1 429 ? -41.940 -1.734  -12.179  1.00 43.76  ? 429 ASP A OD2   1 
ATOM   3338  N  N     . LEU A 1 430 ? -43.730 0.549   -16.027  1.00 37.59  ? 430 LEU A N     1 
ATOM   3339  C  CA    . LEU A 1 430 ? -44.158 -0.348  -17.078  1.00 36.35  ? 430 LEU A CA    1 
ATOM   3340  C  C     . LEU A 1 430 ? -42.971 -1.204  -17.515  1.00 38.80  ? 430 LEU A C     1 
ATOM   3341  O  O     . LEU A 1 430 ? -41.883 -0.684  -17.740  1.00 38.15  ? 430 LEU A O     1 
ATOM   3342  C  CB    . LEU A 1 430 ? -44.671 0.484   -18.259  1.00 38.08  ? 430 LEU A CB    1 
ATOM   3343  C  CG    . LEU A 1 430 ? -45.125 -0.343  -19.464  1.00 38.20  ? 430 LEU A CG    1 
ATOM   3344  C  CD1   . LEU A 1 430 ? -46.444 -1.062  -19.152  1.00 41.94  ? 430 LEU A CD1   1 
ATOM   3345  C  CD2   . LEU A 1 430 ? -45.302 0.531   -20.684  1.00 40.05  ? 430 LEU A CD2   1 
ATOM   3346  N  N     . HIS A 1 431 ? -43.208 -2.509  -17.689  1.00 39.89  ? 431 HIS A N     1 
ATOM   3347  C  CA    . HIS A 1 431 ? -42.279 -3.366  -18.403  1.00 39.64  ? 431 HIS A CA    1 
ATOM   3348  C  C     . HIS A 1 431 ? -42.991 -4.020  -19.586  1.00 41.79  ? 431 HIS A C     1 
ATOM   3349  O  O     . HIS A 1 431 ? -44.003 -4.686  -19.402  1.00 38.55  ? 431 HIS A O     1 
ATOM   3350  C  CB    . HIS A 1 431 ? -41.737 -4.445  -17.474  1.00 38.77  ? 431 HIS A CB    1 
ATOM   3351  C  CG    . HIS A 1 431 ? -41.180 -3.906  -16.220  1.00 41.27  ? 431 HIS A CG    1 
ATOM   3352  N  ND1   . HIS A 1 431 ? -39.832 -3.994  -15.952  1.00 43.93  ? 431 HIS A ND1   1 
ATOM   3353  C  CD2   . HIS A 1 431 ? -41.744 -3.291  -15.183  1.00 43.72  ? 431 HIS A CD2   1 
ATOM   3354  C  CE1   . HIS A 1 431 ? -39.609 -3.456  -14.757  1.00 48.09  ? 431 HIS A CE1   1 
ATOM   3355  N  NE2   . HIS A 1 431 ? -40.754 -3.001  -14.286  1.00 44.20  ? 431 HIS A NE2   1 
ATOM   3356  N  N     . HIS A 1 432 ? -42.466 -3.811  -20.799  1.00 39.17  ? 432 HIS A N     1 
ATOM   3357  C  CA    . HIS A 1 432 ? -42.750 -4.694  -21.915  1.00 37.76  ? 432 HIS A CA    1 
ATOM   3358  C  C     . HIS A 1 432 ? -41.817 -5.904  -21.791  1.00 38.08  ? 432 HIS A C     1 
ATOM   3359  O  O     . HIS A 1 432 ? -40.603 -5.758  -21.910  1.00 39.94  ? 432 HIS A O     1 
ATOM   3360  C  CB    . HIS A 1 432 ? -42.667 -3.965  -23.263  1.00 40.27  ? 432 HIS A CB    1 
ATOM   3361  C  CG    . HIS A 1 432 ? -42.840 -4.925  -24.403  1.00 42.08  ? 432 HIS A CG    1 
ATOM   3362  N  ND1   . HIS A 1 432 ? -44.071 -5.137  -24.987  1.00 40.06  ? 432 HIS A ND1   1 
ATOM   3363  C  CD2   . HIS A 1 432 ? -41.996 -5.783  -24.988  1.00 35.12  ? 432 HIS A CD2   1 
ATOM   3364  C  CE1   . HIS A 1 432 ? -43.956 -6.065  -25.921  1.00 39.10  ? 432 HIS A CE1   1 
ATOM   3365  N  NE2   . HIS A 1 432 ? -42.716 -6.485  -25.925  1.00 42.60  ? 432 HIS A NE2   1 
ATOM   3366  N  N     . VAL A 1 433 ? -42.386 -7.061  -21.440  1.00 35.55  ? 433 VAL A N     1 
ATOM   3367  C  CA    . VAL A 1 433 ? -41.616 -8.274  -21.233  1.00 37.03  ? 433 VAL A CA    1 
ATOM   3368  C  C     . VAL A 1 433 ? -41.755 -9.136  -22.486  1.00 37.55  ? 433 VAL A C     1 
ATOM   3369  O  O     . VAL A 1 433 ? -42.860 -9.505  -22.854  1.00 38.21  ? 433 VAL A O     1 
ATOM   3370  C  CB    . VAL A 1 433 ? -42.050 -9.052  -19.971  1.00 38.71  ? 433 VAL A CB    1 
ATOM   3371  C  CG1   . VAL A 1 433 ? -41.258 -10.342 -19.768  1.00 36.11  ? 433 VAL A CG1   1 
ATOM   3372  C  CG2   . VAL A 1 433 ? -41.965 -8.199  -18.723  1.00 40.43  ? 433 VAL A CG2   1 
ATOM   3373  N  N     . THR A 1 434 ? -40.621 -9.393  -23.144  1.00 40.23  ? 434 THR A N     1 
ATOM   3374  C  CA    . THR A 1 434 ? -40.542 -10.306 -24.267  1.00 43.60  ? 434 THR A CA    1 
ATOM   3375  C  C     . THR A 1 434 ? -40.153 -11.668 -23.709  1.00 40.47  ? 434 THR A C     1 
ATOM   3376  O  O     . THR A 1 434 ? -39.133 -11.773 -23.022  1.00 42.27  ? 434 THR A O     1 
ATOM   3377  C  CB    . THR A 1 434 ? -39.513 -9.807  -25.297  1.00 42.32  ? 434 THR A CB    1 
ATOM   3378  O  OG1   . THR A 1 434 ? -39.743 -8.426  -25.571  1.00 46.42  ? 434 THR A OG1   1 
ATOM   3379  C  CG2   . THR A 1 434 ? -39.552 -10.579 -26.593  1.00 44.45  ? 434 THR A CG2   1 
ATOM   3380  N  N     . VAL A 1 435 ? -40.950 -12.703 -23.999  1.00 41.64  ? 435 VAL A N     1 
ATOM   3381  C  CA    . VAL A 1 435 ? -40.490 -14.067 -23.768  1.00 43.19  ? 435 VAL A CA    1 
ATOM   3382  C  C     . VAL A 1 435 ? -40.341 -14.758 -25.123  1.00 41.94  ? 435 VAL A C     1 
ATOM   3383  O  O     . VAL A 1 435 ? -41.211 -14.674 -25.992  1.00 43.22  ? 435 VAL A O     1 
ATOM   3384  C  CB    . VAL A 1 435 ? -41.361 -14.860 -22.773  1.00 49.02  ? 435 VAL A CB    1 
ATOM   3385  C  CG1   . VAL A 1 435 ? -42.219 -13.940 -21.925  1.00 53.08  ? 435 VAL A CG1   1 
ATOM   3386  C  CG2   . VAL A 1 435 ? -42.213 -15.925 -23.416  1.00 55.03  ? 435 VAL A CG2   1 
ATOM   3387  N  N     . ILE A 1 436 ? -39.168 -15.351 -25.317  1.00 39.45  ? 436 ILE A N     1 
ATOM   3388  C  CA    . ILE A 1 436 ? -38.874 -16.081 -26.530  1.00 42.70  ? 436 ILE A CA    1 
ATOM   3389  C  C     . ILE A 1 436 ? -38.586 -17.525 -26.137  1.00 40.70  ? 436 ILE A C     1 
ATOM   3390  O  O     . ILE A 1 436 ? -37.691 -17.777 -25.337  1.00 41.88  ? 436 ILE A O     1 
ATOM   3391  C  CB    . ILE A 1 436 ? -37.689 -15.459 -27.282  1.00 46.84  ? 436 ILE A CB    1 
ATOM   3392  C  CG1   . ILE A 1 436 ? -37.831 -13.938 -27.443  1.00 50.07  ? 436 ILE A CG1   1 
ATOM   3393  C  CG2   . ILE A 1 436 ? -37.516 -16.182 -28.603  1.00 44.20  ? 436 ILE A CG2   1 
ATOM   3394  C  CD1   . ILE A 1 436 ? -36.502 -13.247 -27.705  1.00 47.57  ? 436 ILE A CD1   1 
ATOM   3395  N  N     . VAL A 1 437 ? -39.392 -18.439 -26.681  1.00 40.98  ? 437 VAL A N     1 
ATOM   3396  C  CA    . VAL A 1 437 ? -39.228 -19.857 -26.453  1.00 42.40  ? 437 VAL A CA    1 
ATOM   3397  C  C     . VAL A 1 437 ? -38.403 -20.371 -27.618  1.00 37.09  ? 437 VAL A C     1 
ATOM   3398  O  O     . VAL A 1 437 ? -38.750 -20.115 -28.752  1.00 41.13  ? 437 VAL A O     1 
ATOM   3399  C  CB    . VAL A 1 437 ? -40.591 -20.563 -26.367  1.00 41.61  ? 437 VAL A CB    1 
ATOM   3400  C  CG1   . VAL A 1 437 ? -40.466 -22.083 -26.311  1.00 44.93  ? 437 VAL A CG1   1 
ATOM   3401  C  CG2   . VAL A 1 437 ? -41.398 -20.042 -25.187  1.00 39.91  ? 437 VAL A CG2   1 
ATOM   3402  N  N     . TYR A 1 438 ? -37.338 -21.111 -27.334  1.00 41.78  ? 438 TYR A N     1 
ATOM   3403  C  CA    . TYR A 1 438 ? -36.463 -21.574 -28.393  1.00 40.50  ? 438 TYR A CA    1 
ATOM   3404  C  C     . TYR A 1 438 ? -36.044 -23.015 -28.114  1.00 42.80  ? 438 TYR A C     1 
ATOM   3405  O  O     . TYR A 1 438 ? -35.998 -23.461 -26.963  1.00 49.96  ? 438 TYR A O     1 
ATOM   3406  C  CB    . TYR A 1 438 ? -35.248 -20.656 -28.515  1.00 40.78  ? 438 TYR A CB    1 
ATOM   3407  C  CG    . TYR A 1 438 ? -34.362 -20.630 -27.299  1.00 43.65  ? 438 TYR A CG    1 
ATOM   3408  C  CD1   . TYR A 1 438 ? -34.770 -19.983 -26.151  1.00 43.19  ? 438 TYR A CD1   1 
ATOM   3409  C  CD2   . TYR A 1 438 ? -33.125 -21.262 -27.274  1.00 50.97  ? 438 TYR A CD2   1 
ATOM   3410  C  CE1   . TYR A 1 438 ? -33.979 -19.960 -25.011  1.00 51.40  ? 438 TYR A CE1   1 
ATOM   3411  C  CE2   . TYR A 1 438 ? -32.324 -21.248 -26.136  1.00 48.25  ? 438 TYR A CE2   1 
ATOM   3412  C  CZ    . TYR A 1 438 ? -32.750 -20.590 -24.998  1.00 49.45  ? 438 TYR A CZ    1 
ATOM   3413  O  OH    . TYR A 1 438 ? -32.025 -20.499 -23.823  1.00 58.42  ? 438 TYR A OH    1 
ATOM   3414  N  N     . ASP A 1 439 ? -35.694 -23.734 -29.178  1.00 47.26  ? 439 ASP A N     1 
ATOM   3415  C  CA    . ASP A 1 439 ? -35.137 -25.070 -29.014  1.00 44.00  ? 439 ASP A CA    1 
ATOM   3416  C  C     . ASP A 1 439 ? -33.678 -24.946 -28.588  1.00 42.67  ? 439 ASP A C     1 
ATOM   3417  O  O     . ASP A 1 439 ? -32.791 -24.728 -29.404  1.00 48.48  ? 439 ASP A O     1 
ATOM   3418  C  CB    . ASP A 1 439 ? -35.329 -25.897 -30.283  1.00 43.50  ? 439 ASP A CB    1 
ATOM   3419  C  CG    . ASP A 1 439 ? -34.655 -27.255 -30.198  1.00 51.86  ? 439 ASP A CG    1 
ATOM   3420  O  OD1   . ASP A 1 439 ? -33.975 -27.539 -29.168  1.00 49.15  ? 439 ASP A OD1   1 
ATOM   3421  O  OD2   . ASP A 1 439 ? -34.759 -27.987 -31.178  1.00 50.68  ? 439 ASP A OD2   1 
ATOM   3422  N  N     . LYS A 1 440 ? -33.447 -25.148 -27.294  1.00 45.61  ? 440 LYS A N     1 
ATOM   3423  C  CA    . LYS A 1 440 ? -32.150 -25.013 -26.655  1.00 50.05  ? 440 LYS A CA    1 
ATOM   3424  C  C     . LYS A 1 440 ? -31.188 -26.137 -27.046  1.00 52.81  ? 440 LYS A C     1 
ATOM   3425  O  O     . LYS A 1 440 ? -29.990 -26.023 -26.757  1.00 46.52  ? 440 LYS A O     1 
ATOM   3426  C  CB    . LYS A 1 440 ? -32.336 -25.079 -25.138  1.00 56.11  ? 440 LYS A CB    1 
ATOM   3427  C  CG    . LYS A 1 440 ? -32.811 -26.454 -24.672  1.00 71.20  ? 440 LYS A CG    1 
ATOM   3428  C  CD    . LYS A 1 440 ? -33.288 -26.541 -23.259  1.00 77.67  ? 440 LYS A CD    1 
ATOM   3429  C  CE    . LYS A 1 440 ? -33.454 -27.971 -22.793  1.00 81.30  ? 440 LYS A CE    1 
ATOM   3430  N  NZ    . LYS A 1 440 ? -33.567 -28.023 -21.317  1.00 86.55  ? 440 LYS A NZ    1 
ATOM   3431  N  N     . THR A 1 441 ? -31.697 -27.236 -27.630  1.00 49.00  ? 441 THR A N     1 
ATOM   3432  C  CA    . THR A 1 441 ? -30.820 -28.323 -28.069  1.00 52.64  ? 441 THR A CA    1 
ATOM   3433  C  C     . THR A 1 441 ? -30.266 -28.094 -29.480  1.00 56.44  ? 441 THR A C     1 
ATOM   3434  O  O     . THR A 1 441 ? -29.351 -28.798 -29.888  1.00 63.55  ? 441 THR A O     1 
ATOM   3435  C  CB    . THR A 1 441 ? -31.499 -29.702 -28.049  1.00 50.57  ? 441 THR A CB    1 
ATOM   3436  O  OG1   . THR A 1 441 ? -32.403 -29.807 -29.148  1.00 49.64  ? 441 THR A OG1   1 
ATOM   3437  C  CG2   . THR A 1 441 ? -32.262 -29.988 -26.773  1.00 49.28  ? 441 THR A CG2   1 
ATOM   3438  N  N     . ASP A 1 442 ? -30.819 -27.126 -30.226  1.00 59.16  ? 442 ASP A N     1 
ATOM   3439  C  CA    . ASP A 1 442 ? -30.459 -26.901 -31.617  1.00 53.96  ? 442 ASP A CA    1 
ATOM   3440  C  C     . ASP A 1 442 ? -29.500 -25.714 -31.740  1.00 61.10  ? 442 ASP A C     1 
ATOM   3441  O  O     . ASP A 1 442 ? -29.903 -24.581 -31.496  1.00 51.94  ? 442 ASP A O     1 
ATOM   3442  C  CB    . ASP A 1 442 ? -31.708 -26.652 -32.459  1.00 50.61  ? 442 ASP A CB    1 
ATOM   3443  C  CG    . ASP A 1 442 ? -31.386 -26.335 -33.902  1.00 53.09  ? 442 ASP A CG    1 
ATOM   3444  O  OD1   . ASP A 1 442 ? -30.178 -26.320 -34.224  1.00 59.44  ? 442 ASP A OD1   1 
ATOM   3445  O  OD2   . ASP A 1 442 ? -32.341 -26.074 -34.680  1.00 51.45  ? 442 ASP A OD2   1 
ATOM   3446  N  N     . PRO A 1 443 ? -28.232 -25.915 -32.180  1.00 58.70  ? 443 PRO A N     1 
ATOM   3447  C  CA    . PRO A 1 443 ? -27.246 -24.829 -32.243  1.00 57.11  ? 443 PRO A CA    1 
ATOM   3448  C  C     . PRO A 1 443 ? -27.582 -23.672 -33.179  1.00 57.66  ? 443 PRO A C     1 
ATOM   3449  O  O     . PRO A 1 443 ? -27.172 -22.538 -32.933  1.00 53.62  ? 443 PRO A O     1 
ATOM   3450  C  CB    . PRO A 1 443 ? -25.970 -25.512 -32.746  1.00 56.90  ? 443 PRO A CB    1 
ATOM   3451  C  CG    . PRO A 1 443 ? -26.174 -26.975 -32.371  1.00 61.09  ? 443 PRO A CG    1 
ATOM   3452  C  CD    . PRO A 1 443 ? -27.656 -27.208 -32.574  1.00 61.63  ? 443 PRO A CD    1 
ATOM   3453  N  N     . ASP A 1 444 ? -28.331 -23.959 -34.244  1.00 55.70  ? 444 ASP A N     1 
ATOM   3454  C  CA    . ASP A 1 444 ? -28.728 -22.911 -35.161  1.00 54.24  ? 444 ASP A CA    1 
ATOM   3455  C  C     . ASP A 1 444 ? -29.763 -22.011 -34.494  1.00 53.77  ? 444 ASP A C     1 
ATOM   3456  O  O     . ASP A 1 444 ? -29.790 -20.808 -34.766  1.00 46.69  ? 444 ASP A O     1 
ATOM   3457  C  CB    . ASP A 1 444 ? -29.244 -23.484 -36.481  1.00 57.20  ? 444 ASP A CB    1 
ATOM   3458  C  CG    . ASP A 1 444 ? -28.160 -24.156 -37.306  1.00 62.38  ? 444 ASP A CG    1 
ATOM   3459  O  OD1   . ASP A 1 444 ? -27.094 -23.553 -37.473  1.00 66.92  ? 444 ASP A OD1   1 
ATOM   3460  O  OD2   . ASP A 1 444 ? -28.401 -25.272 -37.782  1.00 72.73  ? 444 ASP A OD2   1 
ATOM   3461  N  N     . GLU A 1 445 ? -30.637 -22.602 -33.667  1.00 46.85  ? 445 GLU A N     1 
ATOM   3462  C  CA    . GLU A 1 445 ? -31.681 -21.842 -33.003  1.00 50.75  ? 445 GLU A CA    1 
ATOM   3463  C  C     . GLU A 1 445 ? -31.080 -21.017 -31.864  1.00 48.00  ? 445 GLU A C     1 
ATOM   3464  O  O     . GLU A 1 445 ? -31.517 -19.901 -31.650  1.00 55.33  ? 445 GLU A O     1 
ATOM   3465  C  CB    . GLU A 1 445 ? -32.804 -22.754 -32.513  1.00 57.12  ? 445 GLU A CB    1 
ATOM   3466  C  CG    . GLU A 1 445 ? -33.649 -23.309 -33.642  1.00 65.55  ? 445 GLU A CG    1 
ATOM   3467  C  CD    . GLU A 1 445 ? -34.454 -22.251 -34.368  1.00 68.86  ? 445 GLU A CD    1 
ATOM   3468  O  OE1   . GLU A 1 445 ? -35.318 -21.650 -33.714  1.00 70.29  ? 445 GLU A OE1   1 
ATOM   3469  O  OE2   . GLU A 1 445 ? -34.188 -22.010 -35.572  1.00 70.54  ? 445 GLU A OE2   1 
ATOM   3470  N  N     . ARG A 1 446 ? -30.062 -21.537 -31.165  1.00 51.82  ? 446 ARG A N     1 
ATOM   3471  C  CA    . ARG A 1 446 ? -29.401 -20.797 -30.096  1.00 51.47  ? 446 ARG A CA    1 
ATOM   3472  C  C     . ARG A 1 446 ? -28.735 -19.534 -30.648  1.00 48.62  ? 446 ARG A C     1 
ATOM   3473  O  O     . ARG A 1 446 ? -28.799 -18.476 -30.031  1.00 45.21  ? 446 ARG A O     1 
ATOM   3474  C  CB    . ARG A 1 446 ? -28.362 -21.666 -29.376  1.00 51.48  ? 446 ARG A CB    1 
ATOM   3475  C  CG    . ARG A 1 446 ? -28.949 -22.867 -28.647  1.00 48.84  ? 446 ARG A CG    1 
ATOM   3476  C  CD    . ARG A 1 446 ? -27.999 -23.558 -27.695  1.00 49.32  ? 446 ARG A CD    1 
ATOM   3477  N  NE    . ARG A 1 446 ? -26.851 -24.190 -28.332  1.00 56.86  ? 446 ARG A NE    1 
ATOM   3478  C  CZ    . ARG A 1 446 ? -26.628 -25.508 -28.416  1.00 57.67  ? 446 ARG A CZ    1 
ATOM   3479  N  NH1   . ARG A 1 446 ? -27.550 -26.388 -28.073  1.00 59.02  ? 446 ARG A NH1   1 
ATOM   3480  N  NH2   . ARG A 1 446 ? -25.469 -25.944 -28.869  1.00 56.21  ? 446 ARG A NH2   1 
ATOM   3481  N  N     . LYS A 1 447 ? -28.086 -19.674 -31.808  1.00 48.79  ? 447 LYS A N     1 
ATOM   3482  C  CA    . LYS A 1 447 ? -27.376 -18.593 -32.473  1.00 51.15  ? 447 LYS A CA    1 
ATOM   3483  C  C     . LYS A 1 447 ? -28.364 -17.495 -32.875  1.00 50.25  ? 447 LYS A C     1 
ATOM   3484  O  O     . LYS A 1 447 ? -28.117 -16.305 -32.685  1.00 50.52  ? 447 LYS A O     1 
ATOM   3485  C  CB    . LYS A 1 447 ? -26.613 -19.178 -33.672  1.00 50.97  ? 447 LYS A CB    1 
ATOM   3486  C  CG    . LYS A 1 447 ? -25.968 -18.174 -34.619  1.00 51.55  ? 447 LYS A CG    1 
ATOM   3487  C  CD    . LYS A 1 447 ? -25.147 -17.134 -33.920  1.00 54.25  ? 447 LYS A CD    1 
ATOM   3488  C  CE    . LYS A 1 447 ? -24.236 -16.378 -34.857  1.00 56.55  ? 447 LYS A CE    1 
ATOM   3489  N  NZ    . LYS A 1 447 ? -23.312 -15.497 -34.110  1.00 58.79  ? 447 LYS A NZ    1 
ATOM   3490  N  N     . LYS A 1 448 ? -29.495 -17.892 -33.449  1.00 49.00  ? 448 LYS A N     1 
ATOM   3491  C  CA    . LYS A 1 448 ? -30.540 -16.933 -33.773  1.00 48.91  ? 448 LYS A CA    1 
ATOM   3492  C  C     . LYS A 1 448 ? -31.091 -16.247 -32.523  1.00 45.07  ? 448 LYS A C     1 
ATOM   3493  O  O     . LYS A 1 448 ? -31.324 -15.044 -32.539  1.00 46.94  ? 448 LYS A O     1 
ATOM   3494  C  CB    . LYS A 1 448 ? -31.669 -17.620 -34.529  1.00 49.44  ? 448 LYS A CB    1 
ATOM   3495  C  CG    . LYS A 1 448 ? -31.295 -18.032 -35.943  1.00 53.25  ? 448 LYS A CG    1 
ATOM   3496  C  CD    . LYS A 1 448 ? -32.355 -18.923 -36.531  1.00 52.75  ? 448 LYS A CD    1 
ATOM   3497  C  CE    . LYS A 1 448 ? -33.721 -18.356 -36.258  1.00 44.27  ? 448 LYS A CE    1 
ATOM   3498  N  NZ    . LYS A 1 448 ? -34.747 -19.060 -37.024  1.00 50.32  ? 448 LYS A NZ    1 
ATOM   3499  N  N     . LEU A 1 449 ? -31.307 -17.006 -31.445  1.00 41.37  ? 449 LEU A N     1 
ATOM   3500  C  CA    . LEU A 1 449 ? -31.819 -16.420 -30.225  1.00 44.11  ? 449 LEU A CA    1 
ATOM   3501  C  C     . LEU A 1 449 ? -30.847 -15.365 -29.689  1.00 40.91  ? 449 LEU A C     1 
ATOM   3502  O  O     . LEU A 1 449 ? -31.242 -14.245 -29.414  1.00 41.34  ? 449 LEU A O     1 
ATOM   3503  C  CB    . LEU A 1 449 ? -32.039 -17.492 -29.160  1.00 46.86  ? 449 LEU A CB    1 
ATOM   3504  C  CG    . LEU A 1 449 ? -32.492 -16.865 -27.842  1.00 49.74  ? 449 LEU A CG    1 
ATOM   3505  C  CD1   . LEU A 1 449 ? -33.991 -16.959 -27.712  1.00 48.30  ? 449 LEU A CD1   1 
ATOM   3506  C  CD2   . LEU A 1 449 ? -31.761 -17.441 -26.649  1.00 53.61  ? 449 LEU A CD2   1 
ATOM   3507  N  N     . ASP A 1 450 ? -29.585 -15.758 -29.527  1.00 42.51  ? 450 ASP A N     1 
ATOM   3508  C  CA    . ASP A 1 450 ? -28.539 -14.899 -29.002  1.00 49.33  ? 450 ASP A CA    1 
ATOM   3509  C  C     . ASP A 1 450 ? -28.511 -13.583 -29.784  1.00 47.84  ? 450 ASP A C     1 
ATOM   3510  O  O     . ASP A 1 450 ? -28.491 -12.498 -29.201  1.00 52.68  ? 450 ASP A O     1 
ATOM   3511  C  CB    . ASP A 1 450 ? -27.215 -15.665 -29.004  1.00 49.90  ? 450 ASP A CB    1 
ATOM   3512  C  CG    . ASP A 1 450 ? -26.084 -14.967 -28.271  1.00 60.56  ? 450 ASP A CG    1 
ATOM   3513  O  OD1   . ASP A 1 450 ? -26.331 -14.410 -27.171  1.00 61.75  ? 450 ASP A OD1   1 
ATOM   3514  O  OD2   . ASP A 1 450 ? -24.950 -14.999 -28.794  1.00 63.82  ? 450 ASP A OD2   1 
ATOM   3515  N  N     . GLU A 1 451 ? -28.556 -13.690 -31.112  1.00 44.17  ? 451 GLU A N     1 
ATOM   3516  C  CA    . GLU A 1 451 ? -28.500 -12.536 -31.987  1.00 46.00  ? 451 GLU A CA    1 
ATOM   3517  C  C     . GLU A 1 451 ? -29.741 -11.670 -31.797  1.00 46.94  ? 451 GLU A C     1 
ATOM   3518  O  O     . GLU A 1 451 ? -29.615 -10.449 -31.656  1.00 40.84  ? 451 GLU A O     1 
ATOM   3519  C  CB    . GLU A 1 451 ? -28.364 -12.991 -33.440  1.00 46.61  ? 451 GLU A CB    1 
ATOM   3520  C  CG    . GLU A 1 451 ? -28.359 -11.855 -34.447  1.00 45.70  ? 451 GLU A CG    1 
ATOM   3521  C  CD    . GLU A 1 451 ? -28.284 -12.352 -35.876  1.00 46.44  ? 451 GLU A CD    1 
ATOM   3522  O  OE1   . GLU A 1 451 ? -27.261 -12.985 -36.209  1.00 44.63  ? 451 GLU A OE1   1 
ATOM   3523  O  OE2   . GLU A 1 451 ? -29.256 -12.145 -36.623  1.00 42.10  ? 451 GLU A OE2   1 
ATOM   3524  N  N     . LEU A 1 452 ? -30.932 -12.302 -31.812  1.00 42.85  ? 452 LEU A N     1 
ATOM   3525  C  CA    . LEU A 1 452 ? -32.176 -11.566 -31.628  1.00 39.07  ? 452 LEU A CA    1 
ATOM   3526  C  C     . LEU A 1 452 ? -32.119 -10.817 -30.297  1.00 38.70  ? 452 LEU A C     1 
ATOM   3527  O  O     . LEU A 1 452 ? -32.442 -9.637  -30.245  1.00 39.12  ? 452 LEU A O     1 
ATOM   3528  C  CB    . LEU A 1 452 ? -33.355 -12.533 -31.722  1.00 41.11  ? 452 LEU A CB    1 
ATOM   3529  C  CG    . LEU A 1 452 ? -34.742 -12.003 -31.363  1.00 41.31  ? 452 LEU A CG    1 
ATOM   3530  C  CD1   . LEU A 1 452 ? -35.189 -10.868 -32.275  1.00 40.91  ? 452 LEU A CD1   1 
ATOM   3531  C  CD2   . LEU A 1 452 ? -35.742 -13.151 -31.434  1.00 43.62  ? 452 LEU A CD2   1 
ATOM   3532  N  N     . PHE A 1 453 ? -31.636 -11.494 -29.249  1.00 37.39  ? 453 PHE A N     1 
ATOM   3533  C  CA    . PHE A 1 453 ? -31.629 -10.941 -27.911  1.00 40.86  ? 453 PHE A CA    1 
ATOM   3534  C  C     . PHE A 1 453 ? -30.779 -9.671  -27.871  1.00 39.81  ? 453 PHE A C     1 
ATOM   3535  O  O     . PHE A 1 453 ? -31.224 -8.657  -27.347  1.00 37.78  ? 453 PHE A O     1 
ATOM   3536  C  CB    . PHE A 1 453 ? -31.176 -11.974 -26.877  1.00 41.36  ? 453 PHE A CB    1 
ATOM   3537  C  CG    . PHE A 1 453 ? -31.298 -11.492 -25.449  1.00 42.80  ? 453 PHE A CG    1 
ATOM   3538  C  CD1   . PHE A 1 453 ? -30.289 -10.738 -24.861  1.00 45.13  ? 453 PHE A CD1   1 
ATOM   3539  C  CD2   . PHE A 1 453 ? -32.442 -11.741 -24.715  1.00 44.60  ? 453 PHE A CD2   1 
ATOM   3540  C  CE1   . PHE A 1 453 ? -30.435 -10.240 -23.578  1.00 48.39  ? 453 PHE A CE1   1 
ATOM   3541  C  CE2   . PHE A 1 453 ? -32.579 -11.250 -23.424  1.00 47.52  ? 453 PHE A CE2   1 
ATOM   3542  C  CZ    . PHE A 1 453 ? -31.571 -10.518 -22.852  1.00 44.60  ? 453 PHE A CZ    1 
ATOM   3543  N  N     . ASN A 1 454 ? -29.572 -9.744  -28.431  1.00 39.64  ? 454 ASN A N     1 
ATOM   3544  C  CA    . ASN A 1 454 ? -28.666 -8.612  -28.461  1.00 41.54  ? 454 ASN A CA    1 
ATOM   3545  C  C     . ASN A 1 454 ? -29.294 -7.402  -29.141  1.00 41.86  ? 454 ASN A C     1 
ATOM   3546  O  O     . ASN A 1 454 ? -29.196 -6.284  -28.628  1.00 39.91  ? 454 ASN A O     1 
ATOM   3547  C  CB    . ASN A 1 454 ? -27.321 -8.999  -29.069  1.00 42.12  ? 454 ASN A CB    1 
ATOM   3548  C  CG    . ASN A 1 454 ? -26.442 -9.627  -28.011  1.00 46.63  ? 454 ASN A CG    1 
ATOM   3549  O  OD1   . ASN A 1 454 ? -26.079 -8.968  -27.046  1.00 55.04  ? 454 ASN A OD1   1 
ATOM   3550  N  ND2   . ASN A 1 454 ? -26.122 -10.901 -28.151  1.00 50.98  ? 454 ASN A ND2   1 
ATOM   3551  N  N     . ILE A 1 455 ? -29.906 -7.630  -30.298  1.00 38.11  ? 455 ILE A N     1 
ATOM   3552  C  CA    . ILE A 1 455 ? -30.515 -6.572  -31.076  1.00 39.09  ? 455 ILE A CA    1 
ATOM   3553  C  C     . ILE A 1 455 ? -31.691 -5.963  -30.310  1.00 43.77  ? 455 ILE A C     1 
ATOM   3554  O  O     . ILE A 1 455 ? -31.918 -4.741  -30.360  1.00 38.38  ? 455 ILE A O     1 
ATOM   3555  C  CB    . ILE A 1 455 ? -30.926 -7.095  -32.471  1.00 39.92  ? 455 ILE A CB    1 
ATOM   3556  C  CG1   . ILE A 1 455 ? -29.711 -7.537  -33.291  1.00 43.60  ? 455 ILE A CG1   1 
ATOM   3557  C  CG2   . ILE A 1 455 ? -31.762 -6.071  -33.229  1.00 41.33  ? 455 ILE A CG2   1 
ATOM   3558  C  CD1   . ILE A 1 455 ? -30.071 -8.073  -34.673  1.00 43.02  ? 455 ILE A CD1   1 
ATOM   3559  N  N     . LEU A 1 456 ? -32.476 -6.805  -29.637  1.00 42.10  ? 456 LEU A N     1 
ATOM   3560  C  CA    . LEU A 1 456 ? -33.612 -6.289  -28.874  1.00 40.36  ? 456 LEU A CA    1 
ATOM   3561  C  C     . LEU A 1 456 ? -33.096 -5.347  -27.780  1.00 41.42  ? 456 LEU A C     1 
ATOM   3562  O  O     . LEU A 1 456 ? -33.594 -4.225  -27.612  1.00 36.39  ? 456 LEU A O     1 
ATOM   3563  C  CB    . LEU A 1 456 ? -34.415 -7.454  -28.282  1.00 39.83  ? 456 LEU A CB    1 
ATOM   3564  C  CG    . LEU A 1 456 ? -35.298 -8.232  -29.265  1.00 38.22  ? 456 LEU A CG    1 
ATOM   3565  C  CD1   . LEU A 1 456 ? -36.058 -9.347  -28.561  1.00 38.46  ? 456 LEU A CD1   1 
ATOM   3566  C  CD2   . LEU A 1 456 ? -36.268 -7.313  -29.958  1.00 37.08  ? 456 LEU A CD2   1 
ATOM   3567  N  N     . VAL A 1 457 ? -32.047 -5.797  -27.083  1.00 37.06  ? 457 VAL A N     1 
ATOM   3568  C  CA    . VAL A 1 457 ? -31.459 -5.033  -25.995  1.00 38.53  ? 457 VAL A CA    1 
ATOM   3569  C  C     . VAL A 1 457 ? -30.928 -3.695  -26.516  1.00 42.83  ? 457 VAL A C     1 
ATOM   3570  O  O     . VAL A 1 457 ? -31.203 -2.643  -25.929  1.00 36.70  ? 457 VAL A O     1 
ATOM   3571  C  CB    . VAL A 1 457 ? -30.355 -5.838  -25.293  1.00 41.86  ? 457 VAL A CB    1 
ATOM   3572  C  CG1   . VAL A 1 457 ? -29.551 -4.975  -24.332  1.00 40.32  ? 457 VAL A CG1   1 
ATOM   3573  C  CG2   . VAL A 1 457 ? -30.908 -7.056  -24.567  1.00 45.68  ? 457 VAL A CG2   1 
ATOM   3574  N  N     . ASP A 1 458 ? -30.155 -3.752  -27.618  1.00 44.37  ? 458 ASP A N     1 
ATOM   3575  C  CA    . ASP A 1 458 ? -29.540 -2.576  -28.212  1.00 38.16  ? 458 ASP A CA    1 
ATOM   3576  C  C     . ASP A 1 458 ? -30.615 -1.558  -28.588  1.00 41.08  ? 458 ASP A C     1 
ATOM   3577  O  O     . ASP A 1 458 ? -30.505 -0.382  -28.277  1.00 40.81  ? 458 ASP A O     1 
ATOM   3578  C  CB    . ASP A 1 458 ? -28.716 -2.999  -29.424  1.00 35.61  ? 458 ASP A CB    1 
ATOM   3579  C  CG    . ASP A 1 458 ? -27.437 -3.709  -29.053  1.00 36.72  ? 458 ASP A CG    1 
ATOM   3580  O  OD1   . ASP A 1 458 ? -26.995 -3.528  -27.911  1.00 38.22  ? 458 ASP A OD1   1 
ATOM   3581  O  OD2   . ASP A 1 458 ? -26.905 -4.464  -29.906  1.00 40.45  ? 458 ASP A OD2   1 
ATOM   3582  N  N     . GLU A 1 459 ? -31.673 -2.035  -29.241  1.00 37.96  ? 459 GLU A N     1 
ATOM   3583  C  CA    . GLU A 1 459 ? -32.707 -1.168  -29.760  1.00 38.10  ? 459 GLU A CA    1 
ATOM   3584  C  C     . GLU A 1 459 ? -33.580 -0.614  -28.643  1.00 38.74  ? 459 GLU A C     1 
ATOM   3585  O  O     . GLU A 1 459 ? -34.038 0.528   -28.713  1.00 36.20  ? 459 GLU A O     1 
ATOM   3586  C  CB    . GLU A 1 459 ? -33.506 -1.908  -30.831  1.00 42.77  ? 459 GLU A CB    1 
ATOM   3587  C  CG    . GLU A 1 459 ? -32.636 -2.160  -32.043  1.00 46.94  ? 459 GLU A CG    1 
ATOM   3588  C  CD    . GLU A 1 459 ? -33.269 -2.756  -33.280  1.00 50.24  ? 459 GLU A CD    1 
ATOM   3589  O  OE1   . GLU A 1 459 ? -34.397 -3.311  -33.191  1.00 50.06  ? 459 GLU A OE1   1 
ATOM   3590  O  OE2   . GLU A 1 459 ? -32.604 -2.666  -34.338  1.00 47.31  ? 459 GLU A OE2   1 
ATOM   3591  N  N     . ALA A 1 460 ? -33.810 -1.418  -27.610  1.00 38.75  ? 460 ALA A N     1 
ATOM   3592  C  CA    . ALA A 1 460 ? -34.613 -0.946  -26.503  1.00 40.85  ? 460 ALA A CA    1 
ATOM   3593  C  C     . ALA A 1 460 ? -33.832 0.143   -25.754  1.00 39.56  ? 460 ALA A C     1 
ATOM   3594  O  O     . ALA A 1 460 ? -34.405 1.179   -25.403  1.00 41.25  ? 460 ALA A O     1 
ATOM   3595  C  CB    . ALA A 1 460 ? -35.016 -2.117  -25.635  1.00 41.01  ? 460 ALA A CB    1 
ATOM   3596  N  N     . ALA A 1 461 ? -32.514 -0.068  -25.570  1.00 41.16  ? 461 ALA A N     1 
ATOM   3597  C  CA    . ALA A 1 461 ? -31.692 0.849   -24.787  1.00 43.25  ? 461 ALA A CA    1 
ATOM   3598  C  C     . ALA A 1 461 ? -31.701 2.240   -25.429  1.00 42.07  ? 461 ALA A C     1 
ATOM   3599  O  O     . ALA A 1 461 ? -31.798 3.239   -24.737  1.00 42.76  ? 461 ALA A O     1 
ATOM   3600  C  CB    . ALA A 1 461 ? -30.288 0.310   -24.611  1.00 38.61  ? 461 ALA A CB    1 
ATOM   3601  N  N     . ALA A 1 462 ? -31.694 2.286   -26.760  1.00 42.03  ? 462 ALA A N     1 
ATOM   3602  C  CA    . ALA A 1 462 ? -31.600 3.524   -27.511  1.00 43.96  ? 462 ALA A CA    1 
ATOM   3603  C  C     . ALA A 1 462 ? -32.908 4.304   -27.439  1.00 43.20  ? 462 ALA A C     1 
ATOM   3604  O  O     . ALA A 1 462 ? -32.934 5.515   -27.651  1.00 45.40  ? 462 ALA A O     1 
ATOM   3605  C  CB    . ALA A 1 462 ? -31.233 3.195   -28.948  1.00 44.29  ? 462 ALA A CB    1 
ATOM   3606  N  N     . GLU A 1 463 ? -34.009 3.608   -27.152  1.00 45.52  ? 463 GLU A N     1 
ATOM   3607  C  CA    . GLU A 1 463 ? -35.285 4.273   -26.934  1.00 43.99  ? 463 GLU A CA    1 
ATOM   3608  C  C     . GLU A 1 463 ? -35.462 4.649   -25.462  1.00 45.39  ? 463 GLU A C     1 
ATOM   3609  O  O     . GLU A 1 463 ? -36.514 5.165   -25.095  1.00 44.58  ? 463 GLU A O     1 
ATOM   3610  C  CB    . GLU A 1 463 ? -36.404 3.357   -27.418  1.00 45.52  ? 463 GLU A CB    1 
ATOM   3611  C  CG    . GLU A 1 463 ? -36.331 3.068   -28.904  1.00 45.45  ? 463 GLU A CG    1 
ATOM   3612  C  CD    . GLU A 1 463 ? -36.432 4.298   -29.787  1.00 48.53  ? 463 GLU A CD    1 
ATOM   3613  O  OE1   . GLU A 1 463 ? -37.184 5.214   -29.423  1.00 58.61  ? 463 GLU A OE1   1 
ATOM   3614  O  OE2   . GLU A 1 463 ? -35.786 4.328   -30.846  1.00 62.81  ? 463 GLU A OE2   1 
ATOM   3615  N  N     . GLY A 1 464 ? -34.450 4.363   -24.630  1.00 39.33  ? 464 GLY A N     1 
ATOM   3616  C  CA    . GLY A 1 464 ? -34.470 4.724   -23.214  1.00 48.59  ? 464 GLY A CA    1 
ATOM   3617  C  C     . GLY A 1 464 ? -35.051 3.650   -22.280  1.00 46.39  ? 464 GLY A C     1 
ATOM   3618  O  O     . GLY A 1 464 ? -35.459 3.965   -21.169  1.00 41.88  ? 464 GLY A O     1 
ATOM   3619  N  N     . TYR A 1 465 ? -35.044 2.378   -22.702  1.00 43.67  ? 465 TYR A N     1 
ATOM   3620  C  CA    . TYR A 1 465 ? -35.639 1.311   -21.913  1.00 40.35  ? 465 TYR A CA    1 
ATOM   3621  C  C     . TYR A 1 465 ? -34.546 0.359   -21.458  1.00 37.54  ? 465 TYR A C     1 
ATOM   3622  O  O     . TYR A 1 465 ? -33.918 -0.310  -22.279  1.00 36.90  ? 465 TYR A O     1 
ATOM   3623  C  CB    . TYR A 1 465 ? -36.684 0.543   -22.729  1.00 39.96  ? 465 TYR A CB    1 
ATOM   3624  C  CG    . TYR A 1 465 ? -37.703 1.402   -23.430  1.00 39.97  ? 465 TYR A CG    1 
ATOM   3625  C  CD1   . TYR A 1 465 ? -38.214 2.550   -22.835  1.00 43.79  ? 465 TYR A CD1   1 
ATOM   3626  C  CD2   . TYR A 1 465 ? -38.176 1.062   -24.689  1.00 41.69  ? 465 TYR A CD2   1 
ATOM   3627  C  CE1   . TYR A 1 465 ? -39.141 3.356   -23.481  1.00 44.40  ? 465 TYR A CE1   1 
ATOM   3628  C  CE2   . TYR A 1 465 ? -39.116 1.852   -25.338  1.00 43.35  ? 465 TYR A CE2   1 
ATOM   3629  C  CZ    . TYR A 1 465 ? -39.603 3.002   -24.737  1.00 43.19  ? 465 TYR A CZ    1 
ATOM   3630  O  OH    . TYR A 1 465 ? -40.551 3.769   -25.381  1.00 39.32  ? 465 TYR A OH    1 
ATOM   3631  N  N     . GLY A 1 466 ? -34.326 0.300   -20.143  1.00 36.02  ? 466 GLY A N     1 
ATOM   3632  C  CA    . GLY A 1 466 ? -33.233 -0.479  -19.595  1.00 36.58  ? 466 GLY A CA    1 
ATOM   3633  C  C     . GLY A 1 466 ? -33.718 -1.693  -18.813  1.00 36.31  ? 466 GLY A C     1 
ATOM   3634  O  O     . GLY A 1 466 ? -34.744 -1.639  -18.125  1.00 39.29  ? 466 GLY A O     1 
ATOM   3635  N  N     . GLU A 1 467 ? -32.914 -2.759  -18.883  1.00 36.96  ? 467 GLU A N     1 
ATOM   3636  C  CA    . GLU A 1 467 ? -33.249 -4.040  -18.297  1.00 34.50  ? 467 GLU A CA    1 
ATOM   3637  C  C     . GLU A 1 467 ? -32.929 -3.976  -16.807  1.00 39.18  ? 467 GLU A C     1 
ATOM   3638  O  O     . GLU A 1 467 ? -31.946 -3.350  -16.419  1.00 33.82  ? 467 GLU A O     1 
ATOM   3639  C  CB    . GLU A 1 467 ? -32.473 -5.147  -19.008  1.00 35.23  ? 467 GLU A CB    1 
ATOM   3640  C  CG    . GLU A 1 467 ? -32.656 -6.515  -18.369  1.00 36.48  ? 467 GLU A CG    1 
ATOM   3641  C  CD    . GLU A 1 467 ? -34.086 -7.034  -18.324  1.00 44.03  ? 467 GLU A CD    1 
ATOM   3642  O  OE1   . GLU A 1 467 ? -34.883 -6.616  -17.425  1.00 40.42  ? 467 GLU A OE1   1 
ATOM   3643  O  OE2   . GLU A 1 467 ? -34.412 -7.868  -19.189  1.00 48.73  ? 467 GLU A OE2   1 
ATOM   3644  N  N     . TYR A 1 468 ? -33.765 -4.614  -15.975  1.00 33.55  ? 468 TYR A N     1 
ATOM   3645  C  CA    . TYR A 1 468 ? -33.523 -4.621  -14.542  1.00 37.47  ? 468 TYR A CA    1 
ATOM   3646  C  C     . TYR A 1 468 ? -33.103 -5.986  -13.998  1.00 40.63  ? 468 TYR A C     1 
ATOM   3647  O  O     . TYR A 1 468 ? -32.633 -6.052  -12.859  1.00 40.42  ? 468 TYR A O     1 
ATOM   3648  C  CB    . TYR A 1 468 ? -34.763 -4.160  -13.774  1.00 38.15  ? 468 TYR A CB    1 
ATOM   3649  C  CG    . TYR A 1 468 ? -35.854 -5.186  -13.600  1.00 34.52  ? 468 TYR A CG    1 
ATOM   3650  C  CD1   . TYR A 1 468 ? -36.787 -5.412  -14.594  1.00 35.46  ? 468 TYR A CD1   1 
ATOM   3651  C  CD2   . TYR A 1 468 ? -35.977 -5.908  -12.422  1.00 38.90  ? 468 TYR A CD2   1 
ATOM   3652  C  CE1   . TYR A 1 468 ? -37.835 -6.302  -14.423  1.00 37.36  ? 468 TYR A CE1   1 
ATOM   3653  C  CE2   . TYR A 1 468 ? -36.994 -6.830  -12.247  1.00 36.40  ? 468 TYR A CE2   1 
ATOM   3654  C  CZ    . TYR A 1 468 ? -37.930 -7.026  -13.250  1.00 40.18  ? 468 TYR A CZ    1 
ATOM   3655  O  OH    . TYR A 1 468 ? -38.963 -7.927  -13.098  1.00 40.44  ? 468 TYR A OH    1 
ATOM   3656  N  N     . ARG A 1 469 ? -33.274 -7.046  -14.794  1.00 37.02  ? 469 ARG A N     1 
ATOM   3657  C  CA    . ARG A 1 469 ? -32.922 -8.399  -14.388  1.00 40.06  ? 469 ARG A CA    1 
ATOM   3658  C  C     . ARG A 1 469 ? -32.606 -9.252  -15.624  1.00 38.16  ? 469 ARG A C     1 
ATOM   3659  O  O     . ARG A 1 469 ? -33.314 -9.183  -16.615  1.00 37.18  ? 469 ARG A O     1 
ATOM   3660  C  CB    . ARG A 1 469 ? -34.100 -8.969  -13.604  1.00 41.06  ? 469 ARG A CB    1 
ATOM   3661  C  CG    . ARG A 1 469 ? -33.753 -10.225 -12.838  1.00 45.64  ? 469 ARG A CG    1 
ATOM   3662  C  CD    . ARG A 1 469 ? -35.011 -10.795 -12.234  1.00 49.52  ? 469 ARG A CD    1 
ATOM   3663  N  NE    . ARG A 1 469 ? -34.639 -12.103 -11.734  1.00 50.55  ? 469 ARG A NE    1 
ATOM   3664  C  CZ    . ARG A 1 469 ? -35.516 -13.017 -11.374  1.00 46.54  ? 469 ARG A CZ    1 
ATOM   3665  N  NH1   . ARG A 1 469 ? -36.803 -12.726 -11.411  1.00 43.70  ? 469 ARG A NH1   1 
ATOM   3666  N  NH2   . ARG A 1 469 ? -35.100 -14.213 -10.999  1.00 48.33  ? 469 ARG A NH2   1 
ATOM   3667  N  N     . THR A 1 470 ? -31.531 -10.043 -15.605  1.00 40.21  ? 470 THR A N     1 
ATOM   3668  C  CA    . THR A 1 470 ? -31.087 -10.674 -16.846  1.00 46.42  ? 470 THR A CA    1 
ATOM   3669  C  C     . THR A 1 470 ? -30.386 -12.009 -16.599  1.00 49.45  ? 470 THR A C     1 
ATOM   3670  O  O     . THR A 1 470 ? -30.116 -12.385 -15.464  1.00 41.49  ? 470 THR A O     1 
ATOM   3671  C  CB    . THR A 1 470 ? -30.194 -9.747  -17.679  1.00 41.44  ? 470 THR A CB    1 
ATOM   3672  O  OG1   . THR A 1 470 ? -30.168 -10.214 -19.033  1.00 43.93  ? 470 THR A OG1   1 
ATOM   3673  C  CG2   . THR A 1 470 ? -28.786 -9.635  -17.136  1.00 41.70  ? 470 THR A CG2   1 
ATOM   3674  N  N     . HIS A 1 471 ? -30.159 -12.727 -17.708  1.00 47.39  ? 471 HIS A N     1 
ATOM   3675  C  CA    . HIS A 1 471 ? -29.492 -14.023 -17.733  1.00 45.40  ? 471 HIS A CA    1 
ATOM   3676  C  C     . HIS A 1 471 ? -28.005 -13.800 -17.453  1.00 45.42  ? 471 HIS A C     1 
ATOM   3677  O  O     . HIS A 1 471 ? -27.468 -12.767 -17.834  1.00 39.61  ? 471 HIS A O     1 
ATOM   3678  C  CB    . HIS A 1 471 ? -29.775 -14.675 -19.104  1.00 46.91  ? 471 HIS A CB    1 
ATOM   3679  C  CG    . HIS A 1 471 ? -29.259 -16.059 -19.323  1.00 51.37  ? 471 HIS A CG    1 
ATOM   3680  N  ND1   . HIS A 1 471 ? -27.918 -16.365 -19.447  1.00 51.33  ? 471 HIS A ND1   1 
ATOM   3681  C  CD2   . HIS A 1 471 ? -29.921 -17.233 -19.461  1.00 57.51  ? 471 HIS A CD2   1 
ATOM   3682  C  CE1   . HIS A 1 471 ? -27.782 -17.683 -19.612  1.00 57.15  ? 471 HIS A CE1   1 
ATOM   3683  N  NE2   . HIS A 1 471 ? -28.987 -18.227 -19.625  1.00 54.01  ? 471 HIS A NE2   1 
ATOM   3684  N  N     . ILE A 1 472 ? -27.330 -14.789 -16.833  1.00 47.09  ? 472 ILE A N     1 
ATOM   3685  C  CA    . ILE A 1 472 ? -25.914 -14.692 -16.492  1.00 44.20  ? 472 ILE A CA    1 
ATOM   3686  C  C     . ILE A 1 472 ? -25.086 -14.291 -17.706  1.00 53.22  ? 472 ILE A C     1 
ATOM   3687  O  O     . ILE A 1 472 ? -24.008 -13.708 -17.556  1.00 52.04  ? 472 ILE A O     1 
ATOM   3688  C  CB    . ILE A 1 472 ? -25.387 -16.020 -15.920  1.00 52.46  ? 472 ILE A CB    1 
ATOM   3689  C  CG1   . ILE A 1 472 ? -25.855 -17.211 -16.763  1.00 57.08  ? 472 ILE A CG1   1 
ATOM   3690  C  CG2   . ILE A 1 472 ? -25.767 -16.175 -14.459  1.00 50.98  ? 472 ILE A CG2   1 
ATOM   3691  C  CD1   . ILE A 1 472 ? -25.098 -18.484 -16.508  1.00 63.70  ? 472 ILE A CD1   1 
ATOM   3692  N  N     . ARG A 1 473 ? -25.570 -14.680 -18.895  1.00 50.15  ? 473 ARG A N     1 
ATOM   3693  C  CA    . ARG A 1 473 ? -24.828 -14.513 -20.135  1.00 48.19  ? 473 ARG A CA    1 
ATOM   3694  C  C     . ARG A 1 473 ? -24.784 -13.033 -20.491  1.00 46.01  ? 473 ARG A C     1 
ATOM   3695  O  O     . ARG A 1 473 ? -23.815 -12.593 -21.089  1.00 35.91  ? 473 ARG A O     1 
ATOM   3696  C  CB    . ARG A 1 473 ? -25.470 -15.348 -21.257  1.00 53.57  ? 473 ARG A CB    1 
ATOM   3697  C  CG    . ARG A 1 473 ? -24.826 -15.174 -22.627  1.00 61.81  ? 473 ARG A CG    1 
ATOM   3698  C  CD    . ARG A 1 473 ? -25.373 -16.111 -23.693  1.00 63.43  ? 473 ARG A CD    1 
ATOM   3699  N  NE    . ARG A 1 473 ? -24.721 -15.909 -24.988  1.00 64.47  ? 473 ARG A NE    1 
ATOM   3700  C  CZ    . ARG A 1 473 ? -23.462 -16.242 -25.286  1.00 62.23  ? 473 ARG A CZ    1 
ATOM   3701  N  NH1   . ARG A 1 473 ? -22.666 -16.815 -24.395  1.00 61.35  ? 473 ARG A NH1   1 
ATOM   3702  N  NH2   . ARG A 1 473 ? -22.997 -16.010 -26.501  1.00 62.69  ? 473 ARG A NH2   1 
ATOM   3703  N  N     . TYR A 1 474 ? -25.823 -12.271 -20.108  1.00 44.17  ? 474 TYR A N     1 
ATOM   3704  C  CA    . TYR A 1 474 ? -25.981 -10.900 -20.575  1.00 48.06  ? 474 TYR A CA    1 
ATOM   3705  C  C     . TYR A 1 474 ? -25.705 -9.880  -19.459  1.00 41.57  ? 474 TYR A C     1 
ATOM   3706  O  O     . TYR A 1 474 ? -26.018 -8.700  -19.589  1.00 45.24  ? 474 TYR A O     1 
ATOM   3707  C  CB    . TYR A 1 474 ? -27.377 -10.759 -21.197  1.00 52.22  ? 474 TYR A CB    1 
ATOM   3708  C  CG    . TYR A 1 474 ? -27.636 -11.725 -22.332  1.00 52.85  ? 474 TYR A CG    1 
ATOM   3709  C  CD1   . TYR A 1 474 ? -26.852 -11.727 -23.482  1.00 54.98  ? 474 TYR A CD1   1 
ATOM   3710  C  CD2   . TYR A 1 474 ? -28.653 -12.661 -22.244  1.00 48.11  ? 474 TYR A CD2   1 
ATOM   3711  C  CE1   . TYR A 1 474 ? -27.061 -12.652 -24.497  1.00 53.92  ? 474 TYR A CE1   1 
ATOM   3712  C  CE2   . TYR A 1 474 ? -28.895 -13.567 -23.260  1.00 53.78  ? 474 TYR A CE2   1 
ATOM   3713  C  CZ    . TYR A 1 474 ? -28.092 -13.574 -24.388  1.00 55.96  ? 474 TYR A CZ    1 
ATOM   3714  O  OH    . TYR A 1 474 ? -28.369 -14.504 -25.366  1.00 60.18  ? 474 TYR A OH    1 
ATOM   3715  N  N     . MET A 1 475 ? -25.087 -10.324 -18.366  1.00 42.52  ? 475 MET A N     1 
ATOM   3716  C  CA    . MET A 1 475 ? -24.953 -9.502  -17.175  1.00 42.62  ? 475 MET A CA    1 
ATOM   3717  C  C     . MET A 1 475 ? -24.033 -8.318  -17.433  1.00 43.06  ? 475 MET A C     1 
ATOM   3718  O  O     . MET A 1 475 ? -24.374 -7.192  -17.082  1.00 42.76  ? 475 MET A O     1 
ATOM   3719  C  CB    . MET A 1 475 ? -24.431 -10.317 -15.993  1.00 41.54  ? 475 MET A CB    1 
ATOM   3720  C  CG    . MET A 1 475 ? -25.583 -10.983 -15.250  1.00 37.90  ? 475 MET A CG    1 
ATOM   3721  S  SD    . MET A 1 475 ? -25.092 -12.011 -13.903  1.00 39.78  ? 475 MET A SD    1 
ATOM   3722  C  CE    . MET A 1 475 ? -26.742 -12.604 -13.512  1.00 45.65  ? 475 MET A CE    1 
ATOM   3723  N  N     . ASP A 1 476 ? -22.899 -8.577  -18.085  1.00 39.26  ? 476 ASP A N     1 
ATOM   3724  C  CA    . ASP A 1 476 ? -22.031 -7.509  -18.543  1.00 44.02  ? 476 ASP A CA    1 
ATOM   3725  C  C     . ASP A 1 476 ? -22.782 -6.576  -19.486  1.00 42.89  ? 476 ASP A C     1 
ATOM   3726  O  O     . ASP A 1 476 ? -22.726 -5.360  -19.320  1.00 41.88  ? 476 ASP A O     1 
ATOM   3727  C  CB    . ASP A 1 476 ? -20.771 -8.038  -19.222  1.00 42.81  ? 476 ASP A CB    1 
ATOM   3728  C  CG    . ASP A 1 476 ? -19.786 -8.611  -18.231  1.00 46.59  ? 476 ASP A CG    1 
ATOM   3729  O  OD1   . ASP A 1 476 ? -19.626 -7.999  -17.181  1.00 53.27  ? 476 ASP A OD1   1 
ATOM   3730  O  OD2   . ASP A 1 476 ? -19.191 -9.661  -18.524  1.00 62.49  ? 476 ASP A OD2   1 
ATOM   3731  N  N     . ARG A 1 477 ? -23.488 -7.148  -20.465  1.00 41.14  ? 477 ARG A N     1 
ATOM   3732  C  CA    . ARG A 1 477 ? -24.145 -6.336  -21.477  1.00 44.07  ? 477 ARG A CA    1 
ATOM   3733  C  C     . ARG A 1 477 ? -25.118 -5.382  -20.788  1.00 40.01  ? 477 ARG A C     1 
ATOM   3734  O  O     . ARG A 1 477 ? -25.157 -4.190  -21.099  1.00 40.15  ? 477 ARG A O     1 
ATOM   3735  C  CB    . ARG A 1 477 ? -24.794 -7.245  -22.532  1.00 46.45  ? 477 ARG A CB    1 
ATOM   3736  C  CG    . ARG A 1 477 ? -25.786 -6.561  -23.467  1.00 48.96  ? 477 ARG A CG    1 
ATOM   3737  C  CD    . ARG A 1 477 ? -25.250 -5.593  -24.523  1.00 64.44  ? 477 ARG A CD    1 
ATOM   3738  N  NE    . ARG A 1 477 ? -24.954 -4.257  -24.015  1.00 73.77  ? 477 ARG A NE    1 
ATOM   3739  C  CZ    . ARG A 1 477 ? -25.635 -3.140  -24.278  1.00 74.01  ? 477 ARG A CZ    1 
ATOM   3740  N  NH1   . ARG A 1 477 ? -26.610 -3.106  -25.170  1.00 61.28  ? 477 ARG A NH1   1 
ATOM   3741  N  NH2   . ARG A 1 477 ? -25.301 -2.024  -23.656  1.00 86.53  ? 477 ARG A NH2   1 
ATOM   3742  N  N     . ILE A 1 478 ? -25.930 -5.898  -19.859  1.00 41.04  ? 478 ILE A N     1 
ATOM   3743  C  CA    . ILE A 1 478 ? -26.954 -5.054  -19.252  1.00 40.07  ? 478 ILE A CA    1 
ATOM   3744  C  C     . ILE A 1 478 ? -26.288 -3.956  -18.424  1.00 40.70  ? 478 ILE A C     1 
ATOM   3745  O  O     . ILE A 1 478 ? -26.750 -2.814  -18.437  1.00 39.93  ? 478 ILE A O     1 
ATOM   3746  C  CB    . ILE A 1 478 ? -27.977 -5.867  -18.444  1.00 41.56  ? 478 ILE A CB    1 
ATOM   3747  C  CG1   . ILE A 1 478 ? -28.689 -6.884  -19.346  1.00 42.28  ? 478 ILE A CG1   1 
ATOM   3748  C  CG2   . ILE A 1 478 ? -28.980 -4.944  -17.771  1.00 43.66  ? 478 ILE A CG2   1 
ATOM   3749  C  CD1   . ILE A 1 478 ? -29.325 -6.265  -20.580  1.00 41.83  ? 478 ILE A CD1   1 
ATOM   3750  N  N     . ALA A 1 479 ? -25.181 -4.302  -17.756  1.00 38.32  ? 479 ALA A N     1 
ATOM   3751  C  CA    . ALA A 1 479 ? -24.439 -3.356  -16.936  1.00 41.43  ? 479 ALA A CA    1 
ATOM   3752  C  C     . ALA A 1 479 ? -23.971 -2.154  -17.753  1.00 46.25  ? 479 ALA A C     1 
ATOM   3753  O  O     . ALA A 1 479 ? -23.946 -1.036  -17.239  1.00 43.16  ? 479 ALA A O     1 
ATOM   3754  C  CB    . ALA A 1 479 ? -23.262 -4.060  -16.326  1.00 44.63  ? 479 ALA A CB    1 
ATOM   3755  N  N     . LYS A 1 480 ? -23.589 -2.399  -19.022  1.00 44.77  ? 480 LYS A N     1 
ATOM   3756  C  CA    . LYS A 1 480 ? -23.119 -1.346  -19.912  1.00 43.35  ? 480 LYS A CA    1 
ATOM   3757  C  C     . LYS A 1 480 ? -24.232 -0.401  -20.332  1.00 41.75  ? 480 LYS A C     1 
ATOM   3758  O  O     . LYS A 1 480 ? -23.933 0.693   -20.792  1.00 46.52  ? 480 LYS A O     1 
ATOM   3759  C  CB    . LYS A 1 480 ? -22.474 -1.926  -21.169  1.00 49.40  ? 480 LYS A CB    1 
ATOM   3760  C  CG    . LYS A 1 480 ? -21.209 -2.734  -20.919  1.00 55.56  ? 480 LYS A CG    1 
ATOM   3761  C  CD    . LYS A 1 480 ? -20.586 -3.223  -22.218  1.00 66.83  ? 480 LYS A CD    1 
ATOM   3762  C  CE    . LYS A 1 480 ? -19.899 -4.562  -22.073  1.00 72.51  ? 480 LYS A CE    1 
ATOM   3763  N  NZ    . LYS A 1 480 ? -18.927 -4.545  -20.956  1.00 72.86  ? 480 LYS A NZ    1 
ATOM   3764  N  N     . THR A 1 481 ? -25.501 -0.808  -20.173  1.00 39.98  ? 481 THR A N     1 
ATOM   3765  C  CA    . THR A 1 481 ? -26.631 0.086   -20.361  1.00 37.42  ? 481 THR A CA    1 
ATOM   3766  C  C     . THR A 1 481 ? -26.547 1.329   -19.464  1.00 37.93  ? 481 THR A C     1 
ATOM   3767  O  O     . THR A 1 481 ? -27.032 2.401   -19.806  1.00 38.97  ? 481 THR A O     1 
ATOM   3768  C  CB    . THR A 1 481 ? -27.956 -0.569  -19.942  1.00 41.93  ? 481 THR A CB    1 
ATOM   3769  O  OG1   . THR A 1 481 ? -28.108 -1.891  -20.440  1.00 48.30  ? 481 THR A OG1   1 
ATOM   3770  C  CG2   . THR A 1 481 ? -29.168 0.229   -20.368  1.00 46.21  ? 481 THR A CG2   1 
ATOM   3771  N  N     . TYR A 1 482 ? -26.077 1.128   -18.239  1.00 40.87  ? 482 TYR A N     1 
ATOM   3772  C  CA    . TYR A 1 482 ? -26.176 2.115   -17.170  1.00 42.69  ? 482 TYR A CA    1 
ATOM   3773  C  C     . TYR A 1 482 ? -24.880 2.915   -17.116  1.00 41.91  ? 482 TYR A C     1 
ATOM   3774  O  O     . TYR A 1 482 ? -24.214 2.928   -16.095  1.00 44.86  ? 482 TYR A O     1 
ATOM   3775  C  CB    . TYR A 1 482 ? -26.482 1.364   -15.866  1.00 40.89  ? 482 TYR A CB    1 
ATOM   3776  C  CG    . TYR A 1 482 ? -27.860 0.745   -15.898  1.00 38.20  ? 482 TYR A CG    1 
ATOM   3777  C  CD1   . TYR A 1 482 ? -28.978 1.513   -15.625  1.00 37.83  ? 482 TYR A CD1   1 
ATOM   3778  C  CD2   . TYR A 1 482 ? -28.057 -0.569  -16.292  1.00 35.52  ? 482 TYR A CD2   1 
ATOM   3779  C  CE1   . TYR A 1 482 ? -30.257 0.996   -15.730  1.00 38.29  ? 482 TYR A CE1   1 
ATOM   3780  C  CE2   . TYR A 1 482 ? -29.332 -1.106  -16.410  1.00 34.90  ? 482 TYR A CE2   1 
ATOM   3781  C  CZ    . TYR A 1 482 ? -30.435 -0.323  -16.121  1.00 37.06  ? 482 TYR A CZ    1 
ATOM   3782  O  OH    . TYR A 1 482 ? -31.710 -0.808  -16.206  1.00 40.05  ? 482 TYR A OH    1 
ATOM   3783  N  N     . SER A 1 483 ? -24.567 3.601   -18.224  1.00 43.16  ? 483 SER A N     1 
ATOM   3784  C  CA    . SER A 1 483 ? -23.220 4.060   -18.514  1.00 40.89  ? 483 SER A CA    1 
ATOM   3785  C  C     . SER A 1 483 ? -23.062 5.562   -18.277  1.00 42.94  ? 483 SER A C     1 
ATOM   3786  O  O     . SER A 1 483 ? -22.029 6.126   -18.636  1.00 41.80  ? 483 SER A O     1 
ATOM   3787  C  CB    . SER A 1 483 ? -22.877 3.738   -19.941  1.00 40.83  ? 483 SER A CB    1 
ATOM   3788  O  OG    . SER A 1 483 ? -23.941 4.167   -20.768  1.00 40.47  ? 483 SER A OG    1 
ATOM   3789  N  N     . TRP A 1 484 ? -24.069 6.223   -17.695  1.00 37.37  ? 484 TRP A N     1 
ATOM   3790  C  CA    . TRP A 1 484 ? -23.983 7.668   -17.517  1.00 37.85  ? 484 TRP A CA    1 
ATOM   3791  C  C     . TRP A 1 484 ? -22.683 8.061   -16.812  1.00 37.38  ? 484 TRP A C     1 
ATOM   3792  O  O     . TRP A 1 484 ? -22.304 7.454   -15.811  1.00 36.07  ? 484 TRP A O     1 
ATOM   3793  C  CB    . TRP A 1 484 ? -25.189 8.191   -16.749  1.00 40.65  ? 484 TRP A CB    1 
ATOM   3794  C  CG    . TRP A 1 484 ? -25.234 9.682   -16.653  1.00 38.22  ? 484 TRP A CG    1 
ATOM   3795  C  CD1   . TRP A 1 484 ? -25.718 10.555  -17.578  1.00 37.69  ? 484 TRP A CD1   1 
ATOM   3796  C  CD2   . TRP A 1 484 ? -24.770 10.471  -15.543  1.00 35.50  ? 484 TRP A CD2   1 
ATOM   3797  N  NE1   . TRP A 1 484 ? -25.604 11.839  -17.110  1.00 40.94  ? 484 TRP A NE1   1 
ATOM   3798  C  CE2   . TRP A 1 484 ? -25.017 11.818  -15.868  1.00 39.67  ? 484 TRP A CE2   1 
ATOM   3799  C  CE3   . TRP A 1 484 ? -24.184 10.167  -14.305  1.00 33.06  ? 484 TRP A CE3   1 
ATOM   3800  C  CZ2   . TRP A 1 484 ? -24.698 12.862  -14.995  1.00 38.93  ? 484 TRP A CZ2   1 
ATOM   3801  C  CZ3   . TRP A 1 484 ? -23.878 11.202  -13.449  1.00 35.89  ? 484 TRP A CZ3   1 
ATOM   3802  C  CH2   . TRP A 1 484 ? -24.121 12.532  -13.790  1.00 32.74  ? 484 TRP A CH2   1 
ATOM   3803  N  N     . ASN A 1 485 ? -22.029 9.100   -17.348  1.00 36.44  ? 485 ASN A N     1 
ATOM   3804  C  CA    . ASN A 1 485 ? -20.765 9.629   -16.846  1.00 38.02  ? 485 ASN A CA    1 
ATOM   3805  C  C     . ASN A 1 485 ? -19.689 8.539   -16.812  1.00 41.02  ? 485 ASN A C     1 
ATOM   3806  O  O     . ASN A 1 485 ? -19.147 8.203   -15.760  1.00 37.25  ? 485 ASN A O     1 
ATOM   3807  C  CB    . ASN A 1 485 ? -20.958 10.352  -15.511  1.00 36.40  ? 485 ASN A CB    1 
ATOM   3808  C  CG    . ASN A 1 485 ? -19.690 11.041  -15.037  1.00 38.99  ? 485 ASN A CG    1 
ATOM   3809  O  OD1   . ASN A 1 485 ? -18.838 11.418  -15.846  1.00 40.38  ? 485 ASN A OD1   1 
ATOM   3810  N  ND2   . ASN A 1 485 ? -19.519 11.128  -13.726  1.00 35.32  ? 485 ASN A ND2   1 
ATOM   3811  N  N     . ASP A 1 486 ? -19.387 7.995   -17.999  1.00 40.61  ? 486 ASP A N     1 
ATOM   3812  C  CA    . ASP A 1 486 ? -18.335 7.003   -18.182  1.00 44.43  ? 486 ASP A CA    1 
ATOM   3813  C  C     . ASP A 1 486 ? -18.448 5.867   -17.156  1.00 41.02  ? 486 ASP A C     1 
ATOM   3814  O  O     . ASP A 1 486 ? -17.463 5.489   -16.508  1.00 38.20  ? 486 ASP A O     1 
ATOM   3815  C  CB    . ASP A 1 486 ? -16.965 7.676   -18.115  1.00 43.83  ? 486 ASP A CB    1 
ATOM   3816  C  CG    . ASP A 1 486 ? -15.822 6.814   -18.629  1.00 45.66  ? 486 ASP A CG    1 
ATOM   3817  O  OD1   . ASP A 1 486 ? -16.071 5.933   -19.455  1.00 49.97  ? 486 ASP A OD1   1 
ATOM   3818  O  OD2   . ASP A 1 486 ? -14.697 7.010   -18.169  1.00 44.09  ? 486 ASP A OD2   1 
ATOM   3819  N  N     . ASN A 1 487 ? -19.667 5.349   -16.982  1.00 40.62  ? 487 ASN A N     1 
ATOM   3820  C  CA    . ASN A 1 487 ? -19.904 4.180   -16.143  1.00 38.33  ? 487 ASN A CA    1 
ATOM   3821  C  C     . ASN A 1 487 ? -19.627 4.516   -14.680  1.00 35.53  ? 487 ASN A C     1 
ATOM   3822  O  O     . ASN A 1 487 ? -19.069 3.700   -13.943  1.00 38.83  ? 487 ASN A O     1 
ATOM   3823  C  CB    . ASN A 1 487 ? -19.065 2.991   -16.620  1.00 38.67  ? 487 ASN A CB    1 
ATOM   3824  C  CG    . ASN A 1 487 ? -19.397 2.626   -18.053  1.00 41.58  ? 487 ASN A CG    1 
ATOM   3825  O  OD1   . ASN A 1 487 ? -18.591 2.793   -18.964  1.00 44.74  ? 487 ASN A OD1   1 
ATOM   3826  N  ND2   . ASN A 1 487 ? -20.619 2.197   -18.276  1.00 39.68  ? 487 ASN A ND2   1 
ATOM   3827  N  N     . ALA A 1 488 ? -20.054 5.705   -14.252  1.00 37.13  ? 488 ALA A N     1 
ATOM   3828  C  CA    . ALA A 1 488 ? -19.701 6.181   -12.920  1.00 39.30  ? 488 ALA A CA    1 
ATOM   3829  C  C     . ALA A 1 488 ? -20.278 5.241   -11.862  1.00 39.08  ? 488 ALA A C     1 
ATOM   3830  O  O     . ALA A 1 488 ? -19.633 4.989   -10.842  1.00 39.62  ? 488 ALA A O     1 
ATOM   3831  C  CB    . ALA A 1 488 ? -20.192 7.586   -12.711  1.00 39.33  ? 488 ALA A CB    1 
ATOM   3832  N  N     . LEU A 1 489 ? -21.504 4.751   -12.086  1.00 39.51  ? 489 LEU A N     1 
ATOM   3833  C  CA    . LEU A 1 489 ? -22.144 3.909   -11.079  1.00 39.64  ? 489 LEU A CA    1 
ATOM   3834  C  C     . LEU A 1 489 ? -21.363 2.601   -10.889  1.00 39.96  ? 489 LEU A C     1 
ATOM   3835  O  O     . LEU A 1 489 ? -21.068 2.200   -9.753   1.00 38.50  ? 489 LEU A O     1 
ATOM   3836  C  CB    . LEU A 1 489 ? -23.610 3.670   -11.448  1.00 41.34  ? 489 LEU A CB    1 
ATOM   3837  C  CG    . LEU A 1 489 ? -24.370 2.785   -10.454  1.00 41.48  ? 489 LEU A CG    1 
ATOM   3838  C  CD1   . LEU A 1 489 ? -24.125 3.235   -9.020   1.00 43.24  ? 489 LEU A CD1   1 
ATOM   3839  C  CD2   . LEU A 1 489 ? -25.865 2.761   -10.751  1.00 39.26  ? 489 LEU A CD2   1 
ATOM   3840  N  N     . TRP A 1 490 ? -20.969 1.958   -11.998  1.00 34.81  ? 490 TRP A N     1 
ATOM   3841  C  CA    . TRP A 1 490 ? -20.243 0.697   -11.918  1.00 37.83  ? 490 TRP A CA    1 
ATOM   3842  C  C     . TRP A 1 490 ? -18.822 0.900   -11.384  1.00 37.60  ? 490 TRP A C     1 
ATOM   3843  O  O     . TRP A 1 490 ? -18.289 0.003   -10.749  1.00 36.59  ? 490 TRP A O     1 
ATOM   3844  C  CB    . TRP A 1 490 ? -20.275 -0.081  -13.246  1.00 39.09  ? 490 TRP A CB    1 
ATOM   3845  C  CG    . TRP A 1 490 ? -21.224 -1.234  -13.185  1.00 38.11  ? 490 TRP A CG    1 
ATOM   3846  C  CD1   . TRP A 1 490 ? -20.906 -2.566  -13.141  1.00 37.41  ? 490 TRP A CD1   1 
ATOM   3847  C  CD2   . TRP A 1 490 ? -22.655 -1.156  -13.071  1.00 38.67  ? 490 TRP A CD2   1 
ATOM   3848  N  NE1   . TRP A 1 490 ? -22.040 -3.324  -13.009  1.00 36.69  ? 490 TRP A NE1   1 
ATOM   3849  C  CE2   . TRP A 1 490 ? -23.130 -2.484  -12.993  1.00 36.62  ? 490 TRP A CE2   1 
ATOM   3850  C  CE3   . TRP A 1 490 ? -23.576 -0.101  -13.041  1.00 36.32  ? 490 TRP A CE3   1 
ATOM   3851  C  CZ2   . TRP A 1 490 ? -24.483 -2.771  -12.832  1.00 33.62  ? 490 TRP A CZ2   1 
ATOM   3852  C  CZ3   . TRP A 1 490 ? -24.917 -0.392  -12.929  1.00 37.32  ? 490 TRP A CZ3   1 
ATOM   3853  C  CH2   . TRP A 1 490 ? -25.362 -1.710  -12.820  1.00 37.38  ? 490 TRP A CH2   1 
ATOM   3854  N  N     . LYS A 1 491 ? -18.232 2.088   -11.567  1.00 38.22  ? 491 LYS A N     1 
ATOM   3855  C  CA    . LYS A 1 491 ? -16.947 2.386   -10.935  1.00 40.82  ? 491 LYS A CA    1 
ATOM   3856  C  C     . LYS A 1 491 ? -17.107 2.399   -9.416   1.00 38.10  ? 491 LYS A C     1 
ATOM   3857  O  O     . LYS A 1 491 ? -16.230 1.941   -8.690   1.00 36.99  ? 491 LYS A O     1 
ATOM   3858  C  CB    . LYS A 1 491 ? -16.397 3.733   -11.406  1.00 42.81  ? 491 LYS A CB    1 
ATOM   3859  C  CG    . LYS A 1 491 ? -15.823 3.709   -12.813  1.00 45.44  ? 491 LYS A CG    1 
ATOM   3860  C  CD    . LYS A 1 491 ? -15.467 5.080   -13.339  1.00 47.83  ? 491 LYS A CD    1 
ATOM   3861  C  CE    . LYS A 1 491 ? -14.762 4.989   -14.676  1.00 48.52  ? 491 LYS A CE    1 
ATOM   3862  N  NZ    . LYS A 1 491 ? -14.974 6.216   -15.478  1.00 51.81  ? 491 LYS A NZ    1 
ATOM   3863  N  N     . MET A 1 492 ? -18.267 2.873   -8.954   1.00 36.46  ? 492 MET A N     1 
ATOM   3864  C  CA    . MET A 1 492 ? -18.564 2.869   -7.539   1.00 40.00  ? 492 MET A CA    1 
ATOM   3865  C  C     . MET A 1 492 ? -18.803 1.441   -7.056   1.00 41.29  ? 492 MET A C     1 
ATOM   3866  O  O     . MET A 1 492 ? -18.256 1.058   -6.022   1.00 40.86  ? 492 MET A O     1 
ATOM   3867  C  CB    . MET A 1 492 ? -19.788 3.713   -7.194   1.00 41.16  ? 492 MET A CB    1 
ATOM   3868  C  CG    . MET A 1 492 ? -19.911 3.964   -5.688   1.00 40.55  ? 492 MET A CG    1 
ATOM   3869  S  SD    . MET A 1 492 ? -21.518 4.671   -5.284   1.00 43.11  ? 492 MET A SD    1 
ATOM   3870  C  CE    . MET A 1 492 ? -22.514 3.188   -5.356   1.00 47.90  ? 492 MET A CE    1 
ATOM   3871  N  N     . HIS A 1 493 ? -19.624 0.667   -7.781   1.00 41.15  ? 493 HIS A N     1 
ATOM   3872  C  CA    . HIS A 1 493 ? -19.788 -0.747  -7.457   1.00 39.14  ? 493 HIS A CA    1 
ATOM   3873  C  C     . HIS A 1 493 ? -18.427 -1.420  -7.301   1.00 39.19  ? 493 HIS A C     1 
ATOM   3874  O  O     . HIS A 1 493 ? -18.229 -2.089  -6.303   1.00 36.18  ? 493 HIS A O     1 
ATOM   3875  C  CB    . HIS A 1 493 ? -20.624 -1.491  -8.490   1.00 40.53  ? 493 HIS A CB    1 
ATOM   3876  C  CG    . HIS A 1 493 ? -22.032 -1.052  -8.517   1.00 34.70  ? 493 HIS A CG    1 
ATOM   3877  N  ND1   . HIS A 1 493 ? -22.687 -0.621  -7.393   1.00 35.04  ? 493 HIS A ND1   1 
ATOM   3878  C  CD2   . HIS A 1 493 ? -22.936 -1.046  -9.490   1.00 36.07  ? 493 HIS A CD2   1 
ATOM   3879  C  CE1   . HIS A 1 493 ? -23.936 -0.315  -7.700   1.00 34.49  ? 493 HIS A CE1   1 
ATOM   3880  N  NE2   . HIS A 1 493 ? -24.111 -0.557  -8.972   1.00 34.27  ? 493 HIS A NE2   1 
ATOM   3881  N  N     . GLU A 1 494 ? -17.486 -1.163  -8.226   1.00 41.56  ? 494 GLU A N     1 
ATOM   3882  C  CA    . GLU A 1 494 ? -16.176 -1.806  -8.211   1.00 45.22  ? 494 GLU A CA    1 
ATOM   3883  C  C     . GLU A 1 494 ? -15.328 -1.346  -7.023   1.00 43.81  ? 494 GLU A C     1 
ATOM   3884  O  O     . GLU A 1 494 ? -14.532 -2.111  -6.496   1.00 46.10  ? 494 GLU A O     1 
ATOM   3885  C  CB    . GLU A 1 494 ? -15.412 -1.540  -9.515   1.00 47.26  ? 494 GLU A CB    1 
ATOM   3886  C  CG    . GLU A 1 494 ? -15.948 -2.300  -10.719  1.00 53.09  ? 494 GLU A CG    1 
ATOM   3887  C  CD    . GLU A 1 494 ? -15.680 -3.804  -10.790  1.00 56.88  ? 494 GLU A CD    1 
ATOM   3888  O  OE1   . GLU A 1 494 ? -15.010 -4.348  -9.894   1.00 61.51  ? 494 GLU A OE1   1 
ATOM   3889  O  OE2   . GLU A 1 494 ? -16.113 -4.443  -11.784  1.00 63.23  ? 494 GLU A OE2   1 
ATOM   3890  N  N     . THR A 1 495 ? -15.446 -0.078  -6.643   1.00 41.97  ? 495 THR A N     1 
ATOM   3891  C  CA    . THR A 1 495 ? -14.826 0.430   -5.434   1.00 41.91  ? 495 THR A CA    1 
ATOM   3892  C  C     . THR A 1 495 ? -15.281 -0.335  -4.188   1.00 46.31  ? 495 THR A C     1 
ATOM   3893  O  O     . THR A 1 495 ? -14.457 -0.683  -3.355   1.00 40.61  ? 495 THR A O     1 
ATOM   3894  C  CB    . THR A 1 495 ? -15.183 1.906   -5.234   1.00 45.90  ? 495 THR A CB    1 
ATOM   3895  O  OG1   . THR A 1 495 ? -14.682 2.631   -6.355   1.00 43.83  ? 495 THR A OG1   1 
ATOM   3896  C  CG2   . THR A 1 495 ? -14.625 2.475   -3.947   1.00 45.45  ? 495 THR A CG2   1 
ATOM   3897  N  N     . ILE A 1 496 ? -16.596 -0.550  -4.041   1.00 41.26  ? 496 ILE A N     1 
ATOM   3898  C  CA    . ILE A 1 496 ? -17.147 -1.285  -2.914   1.00 41.90  ? 496 ILE A CA    1 
ATOM   3899  C  C     . ILE A 1 496 ? -16.714 -2.751  -3.005   1.00 47.10  ? 496 ILE A C     1 
ATOM   3900  O  O     . ILE A 1 496 ? -16.328 -3.360  -2.007   1.00 48.22  ? 496 ILE A O     1 
ATOM   3901  C  CB    . ILE A 1 496 ? -18.685 -1.114  -2.857   1.00 39.07  ? 496 ILE A CB    1 
ATOM   3902  C  CG1   . ILE A 1 496 ? -19.063 0.355   -2.663   1.00 39.94  ? 496 ILE A CG1   1 
ATOM   3903  C  CG2   . ILE A 1 496 ? -19.279 -1.970  -1.757   1.00 39.84  ? 496 ILE A CG2   1 
ATOM   3904  C  CD1   . ILE A 1 496 ? -20.517 0.665   -2.843   1.00 42.59  ? 496 ILE A CD1   1 
ATOM   3905  N  N     . LYS A 1 497 ? -16.739 -3.309  -4.221   1.00 43.19  ? 497 LYS A N     1 
ATOM   3906  C  CA    . LYS A 1 497 ? -16.338 -4.683  -4.445   1.00 40.58  ? 497 LYS A CA    1 
ATOM   3907  C  C     . LYS A 1 497 ? -14.921 -4.948  -3.950   1.00 39.60  ? 497 LYS A C     1 
ATOM   3908  O  O     . LYS A 1 497 ? -14.680 -5.941  -3.270   1.00 39.49  ? 497 LYS A O     1 
ATOM   3909  C  CB    . LYS A 1 497 ? -16.407 -4.994  -5.934   1.00 42.85  ? 497 LYS A CB    1 
ATOM   3910  C  CG    . LYS A 1 497 ? -16.074 -6.423  -6.311   1.00 40.38  ? 497 LYS A CG    1 
ATOM   3911  C  CD    . LYS A 1 497 ? -16.809 -7.466  -5.545   1.00 39.52  ? 497 LYS A CD    1 
ATOM   3912  C  CE    . LYS A 1 497 ? -16.616 -8.822  -6.196   1.00 42.01  ? 497 LYS A CE    1 
ATOM   3913  N  NZ    . LYS A 1 497 ? -17.310 -9.913  -5.481   1.00 41.69  ? 497 LYS A NZ    1 
ATOM   3914  N  N     . ASP A 1 498 ? -13.990 -4.053  -4.278   1.00 38.10  ? 498 ASP A N     1 
ATOM   3915  C  CA    . ASP A 1 498 ? -12.594 -4.229  -3.901   1.00 44.20  ? 498 ASP A CA    1 
ATOM   3916  C  C     . ASP A 1 498 ? -12.404 -4.041  -2.395   1.00 48.79  ? 498 ASP A C     1 
ATOM   3917  O  O     . ASP A 1 498 ? -11.508 -4.649  -1.808   1.00 50.24  ? 498 ASP A O     1 
ATOM   3918  C  CB    . ASP A 1 498 ? -11.696 -3.283  -4.698   1.00 41.78  ? 498 ASP A CB    1 
ATOM   3919  C  CG    . ASP A 1 498 ? -11.585 -3.664  -6.164   1.00 44.83  ? 498 ASP A CG    1 
ATOM   3920  O  OD1   . ASP A 1 498 ? -11.811 -4.850  -6.479   1.00 49.35  ? 498 ASP A OD1   1 
ATOM   3921  O  OD2   . ASP A 1 498 ? -11.339 -2.762  -6.988   1.00 43.12  ? 498 ASP A OD2   1 
ATOM   3922  N  N     . ALA A 1 499 ? -13.257 -3.217  -1.771   1.00 46.47  ? 499 ALA A N     1 
ATOM   3923  C  CA    . ALA A 1 499 ? -13.163 -2.970  -0.341   1.00 44.47  ? 499 ALA A CA    1 
ATOM   3924  C  C     . ALA A 1 499 ? -13.658 -4.179  0.443    1.00 40.72  ? 499 ALA A C     1 
ATOM   3925  O  O     . ALA A 1 499 ? -13.065 -4.587  1.422    1.00 42.52  ? 499 ALA A O     1 
ATOM   3926  C  CB    . ALA A 1 499 ? -13.965 -1.750  0.005    1.00 48.95  ? 499 ALA A CB    1 
ATOM   3927  N  N     . LEU A 1 500 ? -14.766 -4.756  0.007    1.00 42.41  ? 500 LEU A N     1 
ATOM   3928  C  CA    . LEU A 1 500 ? -15.373 -5.859  0.727    1.00 46.27  ? 500 LEU A CA    1 
ATOM   3929  C  C     . LEU A 1 500 ? -14.742 -7.187  0.320    1.00 44.13  ? 500 LEU A C     1 
ATOM   3930  O  O     . LEU A 1 500 ? -14.702 -8.092  1.147    1.00 41.71  ? 500 LEU A O     1 
ATOM   3931  C  CB    . LEU A 1 500 ? -16.873 -5.878  0.427    1.00 43.75  ? 500 LEU A CB    1 
ATOM   3932  C  CG    . LEU A 1 500 ? -17.670 -4.700  0.987    1.00 43.20  ? 500 LEU A CG    1 
ATOM   3933  C  CD1   . LEU A 1 500 ? -19.138 -4.814  0.575    1.00 45.37  ? 500 LEU A CD1   1 
ATOM   3934  C  CD2   . LEU A 1 500 ? -17.545 -4.651  2.494    1.00 44.55  ? 500 LEU A CD2   1 
ATOM   3935  N  N     . ASP A 1 501 ? -14.328 -7.291  -0.958   1.00 46.27  ? 501 ASP A N     1 
ATOM   3936  C  CA    . ASP A 1 501 ? -13.869 -8.532  -1.565   1.00 44.23  ? 501 ASP A CA    1 
ATOM   3937  C  C     . ASP A 1 501 ? -12.550 -8.308  -2.295   1.00 42.60  ? 501 ASP A C     1 
ATOM   3938  O  O     . ASP A 1 501 ? -12.470 -8.520  -3.492   1.00 42.00  ? 501 ASP A O     1 
ATOM   3939  C  CB    . ASP A 1 501 ? -14.863 -9.111  -2.572   1.00 42.28  ? 501 ASP A CB    1 
ATOM   3940  C  CG    . ASP A 1 501 ? -14.551 -10.554 -2.949   1.00 45.64  ? 501 ASP A CG    1 
ATOM   3941  O  OD1   . ASP A 1 501 ? -13.517 -11.097 -2.458   1.00 52.61  ? 501 ASP A OD1   1 
ATOM   3942  O  OD2   . ASP A 1 501 ? -15.350 -11.146 -3.683   1.00 47.68  ? 501 ASP A OD2   1 
ATOM   3943  N  N     . PRO A 1 502 ? -11.466 -7.906  -1.603   1.00 43.86  ? 502 PRO A N     1 
ATOM   3944  C  CA    . PRO A 1 502 ? -10.220 -7.584  -2.289   1.00 46.44  ? 502 PRO A CA    1 
ATOM   3945  C  C     . PRO A 1 502 ? -9.676  -8.734  -3.134   1.00 47.85  ? 502 PRO A C     1 
ATOM   3946  O  O     . PRO A 1 502 ? -9.088  -8.454  -4.165   1.00 42.90  ? 502 PRO A O     1 
ATOM   3947  C  CB    . PRO A 1 502 ? -9.263  -7.181  -1.155   1.00 46.05  ? 502 PRO A CB    1 
ATOM   3948  C  CG    . PRO A 1 502 ? -9.867  -7.762  0.092    1.00 46.14  ? 502 PRO A CG    1 
ATOM   3949  C  CD    . PRO A 1 502 ? -11.367 -7.757  -0.144   1.00 47.67  ? 502 PRO A CD    1 
ATOM   3950  N  N     . ASN A 1 503 ? -9.907  -10.003 -2.727   1.00 52.03  ? 503 ASN A N     1 
ATOM   3951  C  CA    . ASN A 1 503 ? -9.424  -11.164 -3.469   1.00 48.63  ? 503 ASN A CA    1 
ATOM   3952  C  C     . ASN A 1 503 ? -10.396 -11.584 -4.568   1.00 49.27  ? 503 ASN A C     1 
ATOM   3953  O  O     . ASN A 1 503 ? -10.113 -12.514 -5.310   1.00 53.16  ? 503 ASN A O     1 
ATOM   3954  C  CB    . ASN A 1 503 ? -9.121  -12.359 -2.563   1.00 49.94  ? 503 ASN A CB    1 
ATOM   3955  C  CG    . ASN A 1 503 ? -8.018  -12.052 -1.572   1.00 52.69  ? 503 ASN A CG    1 
ATOM   3956  O  OD1   . ASN A 1 503 ? -7.032  -11.407 -1.915   1.00 53.28  ? 503 ASN A OD1   1 
ATOM   3957  N  ND2   . ASN A 1 503 ? -8.219  -12.421 -0.316   1.00 58.08  ? 503 ASN A ND2   1 
ATOM   3958  N  N     . GLY A 1 504 ? -11.549 -10.922 -4.674   1.00 45.83  ? 504 GLY A N     1 
ATOM   3959  C  CA    . GLY A 1 504 ? -12.452 -11.155 -5.788   1.00 42.24  ? 504 GLY A CA    1 
ATOM   3960  C  C     . GLY A 1 504 ? -12.985 -12.585 -5.818   1.00 44.90  ? 504 GLY A C     1 
ATOM   3961  O  O     . GLY A 1 504 ? -13.252 -13.134 -6.883   1.00 47.97  ? 504 GLY A O     1 
ATOM   3962  N  N     . ILE A 1 505 ? -13.191 -13.184 -4.650   1.00 39.41  ? 505 ILE A N     1 
ATOM   3963  C  CA    . ILE A 1 505 ? -13.597 -14.577 -4.629   1.00 46.20  ? 505 ILE A CA    1 
ATOM   3964  C  C     . ILE A 1 505 ? -15.121 -14.742 -4.674   1.00 45.15  ? 505 ILE A C     1 
ATOM   3965  O  O     . ILE A 1 505 ? -15.582 -15.870 -4.857   1.00 47.65  ? 505 ILE A O     1 
ATOM   3966  C  CB    . ILE A 1 505 ? -12.945 -15.359 -3.473   1.00 49.54  ? 505 ILE A CB    1 
ATOM   3967  C  CG1   . ILE A 1 505 ? -13.226 -14.750 -2.100   1.00 53.82  ? 505 ILE A CG1   1 
ATOM   3968  C  CG2   . ILE A 1 505 ? -11.459 -15.531 -3.732   1.00 54.81  ? 505 ILE A CG2   1 
ATOM   3969  C  CD1   . ILE A 1 505 ? -14.635 -14.994 -1.606   1.00 54.63  ? 505 ILE A CD1   1 
ATOM   3970  N  N     . LEU A 1 506 ? -15.922 -13.670 -4.544   1.00 41.92  ? 506 LEU A N     1 
ATOM   3971  C  CA    . LEU A 1 506 ? -17.364 -13.876 -4.655   1.00 46.27  ? 506 LEU A CA    1 
ATOM   3972  C  C     . LEU A 1 506 ? -17.885 -13.517 -6.046   1.00 41.91  ? 506 LEU A C     1 
ATOM   3973  O  O     . LEU A 1 506 ? -17.878 -12.349 -6.441   1.00 46.97  ? 506 LEU A O     1 
ATOM   3974  C  CB    . LEU A 1 506 ? -18.134 -13.083 -3.602   1.00 47.56  ? 506 LEU A CB    1 
ATOM   3975  C  CG    . LEU A 1 506 ? -18.292 -13.717 -2.222   1.00 58.55  ? 506 LEU A CG    1 
ATOM   3976  C  CD1   . LEU A 1 506 ? -19.465 -13.067 -1.489   1.00 60.18  ? 506 LEU A CD1   1 
ATOM   3977  C  CD2   . LEU A 1 506 ? -18.476 -15.230 -2.281   1.00 55.58  ? 506 LEU A CD2   1 
ATOM   3978  N  N     . ALA A 1 507 ? -18.394 -14.552 -6.721   1.00 44.44  ? 507 ALA A N     1 
ATOM   3979  C  CA    . ALA A 1 507 ? -19.175 -14.489 -7.956   1.00 45.19  ? 507 ALA A CA    1 
ATOM   3980  C  C     . ALA A 1 507 ? -18.681 -13.404 -8.908   1.00 43.99  ? 507 ALA A C     1 
ATOM   3981  O  O     . ALA A 1 507 ? -19.424 -12.488 -9.271   1.00 41.48  ? 507 ALA A O     1 
ATOM   3982  C  CB    . ALA A 1 507 ? -20.648 -14.332 -7.638   1.00 45.01  ? 507 ALA A CB    1 
ATOM   3983  N  N     . PRO A 1 508 ? -17.436 -13.534 -9.412   1.00 48.08  ? 508 PRO A N     1 
ATOM   3984  C  CA    . PRO A 1 508 ? -16.914 -12.602 -10.412  1.00 52.59  ? 508 PRO A CA    1 
ATOM   3985  C  C     . PRO A 1 508 ? -17.840 -12.555 -11.625  1.00 44.32  ? 508 PRO A C     1 
ATOM   3986  O  O     . PRO A 1 508 ? -18.237 -13.605 -12.135  1.00 46.90  ? 508 PRO A O     1 
ATOM   3987  C  CB    . PRO A 1 508 ? -15.531 -13.178 -10.764  1.00 53.89  ? 508 PRO A CB    1 
ATOM   3988  C  CG    . PRO A 1 508 ? -15.177 -14.055 -9.588   1.00 50.88  ? 508 PRO A CG    1 
ATOM   3989  C  CD    . PRO A 1 508 ? -16.498 -14.631 -9.128   1.00 46.97  ? 508 PRO A CD    1 
ATOM   3990  N  N     . GLY A 1 509 ? -18.217 -11.336 -12.037  1.00 37.56  ? 509 GLY A N     1 
ATOM   3991  C  CA    . GLY A 1 509 ? -19.148 -11.148 -13.140  1.00 35.91  ? 509 GLY A CA    1 
ATOM   3992  C  C     . GLY A 1 509 ? -20.614 -10.928 -12.748  1.00 36.34  ? 509 GLY A C     1 
ATOM   3993  O  O     . GLY A 1 509 ? -21.422 -10.484 -13.575  1.00 39.01  ? 509 GLY A O     1 
ATOM   3994  N  N     . LYS A 1 510 ? -21.016 -11.270 -11.526  1.00 33.58  ? 510 LYS A N     1 
ATOM   3995  C  CA    . LYS A 1 510 ? -22.411 -11.049 -11.170  1.00 39.12  ? 510 LYS A CA    1 
ATOM   3996  C  C     . LYS A 1 510 ? -22.715 -9.566  -11.368  1.00 38.15  ? 510 LYS A C     1 
ATOM   3997  O  O     . LYS A 1 510 ? -21.921 -8.730  -10.929  1.00 37.70  ? 510 LYS A O     1 
ATOM   3998  C  CB    . LYS A 1 510 ? -22.687 -11.513 -9.735   1.00 47.19  ? 510 LYS A CB    1 
ATOM   3999  C  CG    . LYS A 1 510 ? -24.085 -11.242 -9.190   1.00 43.19  ? 510 LYS A CG    1 
ATOM   4000  C  CD    . LYS A 1 510 ? -25.256 -11.785 -10.007  1.00 49.52  ? 510 LYS A CD    1 
ATOM   4001  C  CE    . LYS A 1 510 ? -26.606 -11.391 -9.434   1.00 49.60  ? 510 LYS A CE    1 
ATOM   4002  N  NZ    . LYS A 1 510 ? -27.724 -11.686 -10.366  1.00 55.07  ? 510 LYS A NZ    1 
ATOM   4003  N  N     . SER A 1 511 ? -23.812 -9.278  -12.087  1.00 34.74  ? 511 SER A N     1 
ATOM   4004  C  CA    . SER A 1 511 ? -24.249 -7.919  -12.413  1.00 40.09  ? 511 SER A CA    1 
ATOM   4005  C  C     . SER A 1 511 ? -23.164 -7.100  -13.097  1.00 40.70  ? 511 SER A C     1 
ATOM   4006  O  O     . SER A 1 511 ? -23.220 -5.858  -13.126  1.00 41.62  ? 511 SER A O     1 
ATOM   4007  C  CB    . SER A 1 511 ? -24.732 -7.195  -11.206  1.00 40.35  ? 511 SER A CB    1 
ATOM   4008  O  OG    . SER A 1 511 ? -25.785 -7.904  -10.601  1.00 37.26  ? 511 SER A OG    1 
ATOM   4009  N  N     . GLY A 1 512 ? -22.215 -7.825  -13.695  1.00 40.96  ? 512 GLY A N     1 
ATOM   4010  C  CA    . GLY A 1 512 ? -21.105 -7.231  -14.404  1.00 40.69  ? 512 GLY A CA    1 
ATOM   4011  C  C     . GLY A 1 512 ? -20.143 -6.507  -13.468  1.00 42.72  ? 512 GLY A C     1 
ATOM   4012  O  O     . GLY A 1 512 ? -19.513 -5.538  -13.875  1.00 40.05  ? 512 GLY A O     1 
ATOM   4013  N  N     . ILE A 1 513 ? -20.029 -7.011  -12.233  1.00 43.42  ? 513 ILE A N     1 
ATOM   4014  C  CA    . ILE A 1 513 ? -19.068 -6.526  -11.252  1.00 42.24  ? 513 ILE A CA    1 
ATOM   4015  C  C     . ILE A 1 513 ? -17.973 -7.578  -11.112  1.00 39.77  ? 513 ILE A C     1 
ATOM   4016  O  O     . ILE A 1 513 ? -18.269 -8.712  -10.755  1.00 44.23  ? 513 ILE A O     1 
ATOM   4017  C  CB    . ILE A 1 513 ? -19.784 -6.289  -9.906   1.00 39.26  ? 513 ILE A CB    1 
ATOM   4018  C  CG1   . ILE A 1 513 ? -20.936 -5.288  -10.043  1.00 40.20  ? 513 ILE A CG1   1 
ATOM   4019  C  CG2   . ILE A 1 513 ? -18.792 -5.883  -8.832   1.00 39.38  ? 513 ILE A CG2   1 
ATOM   4020  C  CD1   . ILE A 1 513 ? -21.958 -5.330  -8.917   1.00 42.85  ? 513 ILE A CD1   1 
ATOM   4021  N  N     . TRP A 1 514 ? -16.707 -7.188  -11.305  1.00 42.97  ? 514 TRP A N     1 
ATOM   4022  C  CA    . TRP A 1 514 ? -15.654 -8.161  -11.521  1.00 45.09  ? 514 TRP A CA    1 
ATOM   4023  C  C     . TRP A 1 514 ? -14.620 -8.197  -10.392  1.00 47.97  ? 514 TRP A C     1 
ATOM   4024  O  O     . TRP A 1 514 ? -14.141 -9.278  -10.023  1.00 55.06  ? 514 TRP A O     1 
ATOM   4025  C  CB    . TRP A 1 514 ? -15.036 -7.915  -12.904  1.00 43.55  ? 514 TRP A CB    1 
ATOM   4026  C  CG    . TRP A 1 514 ? -15.845 -8.551  -13.995  1.00 41.14  ? 514 TRP A CG    1 
ATOM   4027  C  CD1   . TRP A 1 514 ? -16.732 -7.933  -14.827  1.00 36.30  ? 514 TRP A CD1   1 
ATOM   4028  C  CD2   . TRP A 1 514 ? -15.841 -9.941  -14.376  1.00 41.09  ? 514 TRP A CD2   1 
ATOM   4029  N  NE1   . TRP A 1 514 ? -17.301 -8.845  -15.676  1.00 40.93  ? 514 TRP A NE1   1 
ATOM   4030  C  CE2   . TRP A 1 514 ? -16.776 -10.085 -15.425  1.00 42.89  ? 514 TRP A CE2   1 
ATOM   4031  C  CE3   . TRP A 1 514 ? -15.178 -11.079 -13.913  1.00 44.46  ? 514 TRP A CE3   1 
ATOM   4032  C  CZ2   . TRP A 1 514 ? -17.037 -11.311 -16.030  1.00 43.25  ? 514 TRP A CZ2   1 
ATOM   4033  C  CZ3   . TRP A 1 514 ? -15.442 -12.292 -14.506  1.00 49.41  ? 514 TRP A CZ3   1 
ATOM   4034  C  CH2   . TRP A 1 514 ? -16.347 -12.403 -15.563  1.00 47.79  ? 514 TRP A CH2   1 
ATOM   4035  N  N     . GLY A 1 515 ? -14.229 -7.037  -9.866   1.00 42.69  ? 515 GLY A N     1 
ATOM   4036  C  CA    . GLY A 1 515 ? -13.163 -7.035  -8.872   1.00 44.15  ? 515 GLY A CA    1 
ATOM   4037  C  C     . GLY A 1 515 ? -11.816 -6.769  -9.536   1.00 44.64  ? 515 GLY A C     1 
ATOM   4038  O  O     . GLY A 1 515 ? -11.663 -7.015  -10.734  1.00 43.34  ? 515 GLY A O     1 
ATOM   4039  N  N     . LYS A 1 516 ? -10.855 -6.240  -8.776   1.00 45.75  ? 516 LYS A N     1 
ATOM   4040  C  CA    . LYS A 1 516 ? -9.692  -5.646  -9.413   1.00 52.13  ? 516 LYS A CA    1 
ATOM   4041  C  C     . LYS A 1 516 ? -8.854  -6.722  -10.094  1.00 52.78  ? 516 LYS A C     1 
ATOM   4042  O  O     . LYS A 1 516 ? -8.239  -6.424  -11.107  1.00 53.97  ? 516 LYS A O     1 
ATOM   4043  C  CB    . LYS A 1 516 ? -8.855  -4.786  -8.468   1.00 57.38  ? 516 LYS A CB    1 
ATOM   4044  C  CG    . LYS A 1 516 ? -8.480  -5.358  -7.111   1.00 64.38  ? 516 LYS A CG    1 
ATOM   4045  C  CD    . LYS A 1 516 ? -7.737  -4.320  -6.272   1.00 71.20  ? 516 LYS A CD    1 
ATOM   4046  C  CE    . LYS A 1 516 ? -7.839  -4.540  -4.776   1.00 79.63  ? 516 LYS A CE    1 
ATOM   4047  N  NZ    . LYS A 1 516 ? -7.272  -5.849  -4.374   1.00 81.84  ? 516 LYS A NZ    1 
ATOM   4048  N  N     . ASN A 1 517 ? -8.885  -7.958  -9.574   1.00 53.78  ? 517 ASN A N     1 
ATOM   4049  C  CA    . ASN A 1 517 ? -8.089  -9.046  -10.109  1.00 51.01  ? 517 ASN A CA    1 
ATOM   4050  C  C     . ASN A 1 517 ? -8.532  -9.420  -11.522  1.00 53.12  ? 517 ASN A C     1 
ATOM   4051  O  O     . ASN A 1 517 ? -7.699  -9.827  -12.315  1.00 49.65  ? 517 ASN A O     1 
ATOM   4052  C  CB    . ASN A 1 517 ? -8.140  -10.291 -9.228   1.00 53.37  ? 517 ASN A CB    1 
ATOM   4053  C  CG    . ASN A 1 517 ? -7.487  -10.086 -7.882   1.00 59.36  ? 517 ASN A CG    1 
ATOM   4054  O  OD1   . ASN A 1 517 ? -6.680  -9.176  -7.711   1.00 66.82  ? 517 ASN A OD1   1 
ATOM   4055  N  ND2   . ASN A 1 517 ? -7.835  -10.924 -6.920   1.00 62.92  ? 517 ASN A ND2   1 
ATOM   4056  N  N     . ARG A 1 518 ? -9.819  -9.294  -11.862  1.00 53.36  ? 518 ARG A N     1 
ATOM   4057  C  CA    . ARG A 1 518 ? -10.268 -9.826  -13.141  1.00 50.71  ? 518 ARG A CA    1 
ATOM   4058  C  C     . ARG A 1 518 ? -10.736 -8.726  -14.087  1.00 52.79  ? 518 ARG A C     1 
ATOM   4059  O  O     . ARG A 1 518 ? -11.263 -9.032  -15.144  1.00 60.36  ? 518 ARG A O     1 
ATOM   4060  C  CB    . ARG A 1 518 ? -11.357 -10.872 -12.913  1.00 49.39  ? 518 ARG A CB    1 
ATOM   4061  C  CG    . ARG A 1 518 ? -10.882 -12.076 -12.116  1.00 48.39  ? 518 ARG A CG    1 
ATOM   4062  C  CD    . ARG A 1 518 ? -11.872 -13.201 -12.132  1.00 51.95  ? 518 ARG A CD    1 
ATOM   4063  N  NE    . ARG A 1 518 ? -11.410 -14.313 -11.322  1.00 60.08  ? 518 ARG A NE    1 
ATOM   4064  C  CZ    . ARG A 1 518 ? -10.774 -15.384 -11.792  1.00 70.66  ? 518 ARG A CZ    1 
ATOM   4065  N  NH1   . ARG A 1 518 ? -10.389 -15.434 -13.058  1.00 66.78  ? 518 ARG A NH1   1 
ATOM   4066  N  NH2   . ARG A 1 518 ? -10.496 -16.396 -10.982  1.00 71.34  ? 518 ARG A NH2   1 
ATOM   4067  N  N     . ARG A 1 519 ? -10.496 -7.456  -13.757  1.00 55.38  ? 519 ARG A N     1 
ATOM   4068  C  CA    . ARG A 1 519 ? -11.231 -6.365  -14.381  1.00 59.13  ? 519 ARG A CA    1 
ATOM   4069  C  C     . ARG A 1 519 ? -10.392 -5.732  -15.500  1.00 62.73  ? 519 ARG A C     1 
ATOM   4070  O  O     . ARG A 1 519 ? -9.153  -5.794  -15.370  1.00 68.99  ? 519 ARG A O     1 
ATOM   4071  C  CB    . ARG A 1 519 ? -11.651 -5.395  -13.273  1.00 61.00  ? 519 ARG A CB    1 
ATOM   4072  C  CG    . ARG A 1 519 ? -12.398 -4.158  -13.736  1.00 61.26  ? 519 ARG A CG    1 
ATOM   4073  C  CD    . ARG A 1 519 ? -12.892 -3.298  -12.577  1.00 56.08  ? 519 ARG A CD    1 
ATOM   4074  N  NE    . ARG A 1 519 ? -11.820 -2.695  -11.786  1.00 56.83  ? 519 ARG A NE    1 
ATOM   4075  C  CZ    . ARG A 1 519 ? -11.692 -2.790  -10.458  1.00 59.77  ? 519 ARG A CZ    1 
ATOM   4076  N  NH1   . ARG A 1 519 ? -12.585 -3.440  -9.733   1.00 56.35  ? 519 ARG A NH1   1 
ATOM   4077  N  NH2   . ARG A 1 519 ? -10.658 -2.233  -9.848   1.00 57.64  ? 519 ARG A NH2   1 
ATOM   4078  N  N     . ALA B 1 2   ? 9.277   10.176  -18.756  1.00 73.21  ? 2   ALA B N     1 
ATOM   4079  C  CA    . ALA B 1 2   ? 9.768   9.041   -19.577  1.00 76.75  ? 2   ALA B CA    1 
ATOM   4080  C  C     . ALA B 1 2   ? 8.591   8.139   -19.927  1.00 78.53  ? 2   ALA B C     1 
ATOM   4081  O  O     . ALA B 1 2   ? 7.794   7.805   -19.051  1.00 73.25  ? 2   ALA B O     1 
ATOM   4082  C  CB    . ALA B 1 2   ? 10.847  8.265   -18.853  1.00 77.02  ? 2   ALA B CB    1 
ATOM   4083  N  N     . ALA B 1 3   ? 8.517   7.747   -21.207  1.00 87.39  ? 3   ALA B N     1 
ATOM   4084  C  CA    . ALA B 1 3   ? 7.400   6.994   -21.756  1.00 79.53  ? 3   ALA B CA    1 
ATOM   4085  C  C     . ALA B 1 3   ? 7.651   5.493   -21.610  1.00 75.07  ? 3   ALA B C     1 
ATOM   4086  O  O     . ALA B 1 3   ? 8.736   5.015   -21.946  1.00 76.32  ? 3   ALA B O     1 
ATOM   4087  C  CB    . ALA B 1 3   ? 7.206   7.381   -23.205  1.00 81.58  ? 3   ALA B CB    1 
ATOM   4088  N  N     . PRO B 1 4   ? 6.660   4.694   -21.135  1.00 79.62  ? 4   PRO B N     1 
ATOM   4089  C  CA    . PRO B 1 4   ? 6.846   3.247   -20.997  1.00 80.52  ? 4   PRO B CA    1 
ATOM   4090  C  C     . PRO B 1 4   ? 7.077   2.577   -22.349  1.00 76.73  ? 4   PRO B C     1 
ATOM   4091  O  O     . PRO B 1 4   ? 6.649   3.097   -23.376  1.00 79.65  ? 4   PRO B O     1 
ATOM   4092  C  CB    . PRO B 1 4   ? 5.550   2.730   -20.343  1.00 80.03  ? 4   PRO B CB    1 
ATOM   4093  C  CG    . PRO B 1 4   ? 4.530   3.852   -20.510  1.00 81.41  ? 4   PRO B CG    1 
ATOM   4094  C  CD    . PRO B 1 4   ? 5.320   5.132   -20.701  1.00 81.72  ? 4   PRO B CD    1 
ATOM   4095  N  N     . LEU B 1 5   ? 7.779   1.438   -22.337  1.00 70.11  ? 5   LEU B N     1 
ATOM   4096  C  CA    . LEU B 1 5   ? 7.738   0.508   -23.453  1.00 68.74  ? 5   LEU B CA    1 
ATOM   4097  C  C     . LEU B 1 5   ? 6.279   0.165   -23.737  1.00 71.32  ? 5   LEU B C     1 
ATOM   4098  O  O     . LEU B 1 5   ? 5.455   0.145   -22.820  1.00 63.26  ? 5   LEU B O     1 
ATOM   4099  C  CB    . LEU B 1 5   ? 8.496   -0.776  -23.099  1.00 69.55  ? 5   LEU B CB    1 
ATOM   4100  C  CG    . LEU B 1 5   ? 10.024  -0.715  -23.142  1.00 77.51  ? 5   LEU B CG    1 
ATOM   4101  C  CD1   . LEU B 1 5   ? 10.626  -1.959  -22.503  1.00 79.65  ? 5   LEU B CD1   1 
ATOM   4102  C  CD2   . LEU B 1 5   ? 10.539  -0.574  -24.569  1.00 74.00  ? 5   LEU B CD2   1 
ATOM   4103  N  N     . PRO B 1 6   ? 5.932   -0.190  -24.994  1.00 71.58  ? 6   PRO B N     1 
ATOM   4104  C  CA    . PRO B 1 6   ? 4.606   -0.710  -25.301  1.00 72.30  ? 6   PRO B CA    1 
ATOM   4105  C  C     . PRO B 1 6   ? 4.553   -2.153  -24.801  1.00 71.60  ? 6   PRO B C     1 
ATOM   4106  O  O     . PRO B 1 6   ? 5.477   -2.934  -25.051  1.00 65.39  ? 6   PRO B O     1 
ATOM   4107  C  CB    . PRO B 1 6   ? 4.530   -0.566  -26.826  1.00 73.85  ? 6   PRO B CB    1 
ATOM   4108  C  CG    . PRO B 1 6   ? 5.960   -0.767  -27.286  1.00 72.27  ? 6   PRO B CG    1 
ATOM   4109  C  CD    . PRO B 1 6   ? 6.826   -0.231  -26.161  1.00 71.15  ? 6   PRO B CD    1 
ATOM   4110  N  N     . GLU B 1 7   ? 3.483   -2.472  -24.059  1.00 65.32  ? 7   GLU B N     1 
ATOM   4111  C  CA    . GLU B 1 7   ? 3.311   -3.782  -23.446  1.00 69.58  ? 7   GLU B CA    1 
ATOM   4112  C  C     . GLU B 1 7   ? 3.559   -4.896  -24.468  1.00 66.12  ? 7   GLU B C     1 
ATOM   4113  O  O     . GLU B 1 7   ? 3.070   -4.834  -25.592  1.00 63.61  ? 7   GLU B O     1 
ATOM   4114  C  CB    . GLU B 1 7   ? 1.904   -3.871  -22.855  1.00 76.21  ? 7   GLU B CB    1 
ATOM   4115  C  CG    . GLU B 1 7   ? 1.619   -5.189  -22.167  1.00 83.19  ? 7   GLU B CG    1 
ATOM   4116  C  CD    . GLU B 1 7   ? 0.140   -5.386  -21.898  1.00 90.62  ? 7   GLU B CD    1 
ATOM   4117  O  OE1   . GLU B 1 7   ? -0.413  -4.642  -21.056  1.00 85.72  ? 7   GLU B OE1   1 
ATOM   4118  O  OE2   . GLU B 1 7   ? -0.460  -6.251  -22.567  1.00 95.08  ? 7   GLU B OE2   1 
ATOM   4119  N  N     . GLY B 1 8   ? 4.344   -5.908  -24.075  1.00 63.16  ? 8   GLY B N     1 
ATOM   4120  C  CA    . GLY B 1 8   ? 4.662   -7.029  -24.947  1.00 63.19  ? 8   GLY B CA    1 
ATOM   4121  C  C     . GLY B 1 8   ? 5.953   -6.824  -25.744  1.00 66.56  ? 8   GLY B C     1 
ATOM   4122  O  O     . GLY B 1 8   ? 6.400   -7.735  -26.439  1.00 64.76  ? 8   GLY B O     1 
ATOM   4123  N  N     . VAL B 1 9   ? 6.566   -5.637  -25.649  1.00 62.76  ? 9   VAL B N     1 
ATOM   4124  C  CA    . VAL B 1 9   ? 7.757   -5.360  -26.436  1.00 72.44  ? 9   VAL B CA    1 
ATOM   4125  C  C     . VAL B 1 9   ? 8.946   -5.183  -25.499  1.00 73.90  ? 9   VAL B C     1 
ATOM   4126  O  O     . VAL B 1 9   ? 8.970   -4.267  -24.673  1.00 73.24  ? 9   VAL B O     1 
ATOM   4127  C  CB    . VAL B 1 9   ? 7.573   -4.138  -27.355  1.00 75.38  ? 9   VAL B CB    1 
ATOM   4128  C  CG1   . VAL B 1 9   ? 8.888   -3.689  -27.965  1.00 77.33  ? 9   VAL B CG1   1 
ATOM   4129  C  CG2   . VAL B 1 9   ? 6.547   -4.411  -28.446  1.00 74.36  ? 9   VAL B CG2   1 
ATOM   4130  N  N     . SER B 1 10  ? 9.935   -6.066  -25.676  1.00 81.77  ? 10  SER B N     1 
ATOM   4131  C  CA    . SER B 1 10  ? 11.138  -6.080  -24.862  1.00 79.12  ? 10  SER B CA    1 
ATOM   4132  C  C     . SER B 1 10  ? 11.979  -4.829  -25.120  1.00 89.86  ? 10  SER B C     1 
ATOM   4133  O  O     . SER B 1 10  ? 12.068  -4.359  -26.256  1.00 92.07  ? 10  SER B O     1 
ATOM   4134  C  CB    . SER B 1 10  ? 11.928  -7.328  -25.136  1.00 72.92  ? 10  SER B CB    1 
ATOM   4135  O  OG    . SER B 1 10  ? 12.415  -7.336  -26.466  1.00 74.99  ? 10  SER B OG    1 
ATOM   4136  N  N     . ALA B 1 11  ? 12.613  -4.315  -24.054  1.00 86.77  ? 11  ALA B N     1 
ATOM   4137  C  CA    . ALA B 1 11  ? 13.611  -3.263  -24.173  1.00 79.76  ? 11  ALA B CA    1 
ATOM   4138  C  C     . ALA B 1 11  ? 14.603  -3.583  -25.292  1.00 72.97  ? 11  ALA B C     1 
ATOM   4139  O  O     . ALA B 1 11  ? 15.047  -2.673  -25.984  1.00 71.60  ? 11  ALA B O     1 
ATOM   4140  C  CB    . ALA B 1 11  ? 14.322  -3.063  -22.856  1.00 83.36  ? 11  ALA B CB    1 
ATOM   4141  N  N     . GLU B 1 12  ? 14.942  -4.867  -25.478  1.00 69.28  ? 12  GLU B N     1 
ATOM   4142  C  CA    . GLU B 1 12  ? 15.850  -5.255  -26.544  1.00 75.06  ? 12  GLU B CA    1 
ATOM   4143  C  C     . GLU B 1 12  ? 15.230  -4.899  -27.885  1.00 82.14  ? 12  GLU B C     1 
ATOM   4144  O  O     . GLU B 1 12  ? 15.766  -4.047  -28.588  1.00 80.34  ? 12  GLU B O     1 
ATOM   4145  C  CB    . GLU B 1 12  ? 16.182  -6.748  -26.561  1.00 79.16  ? 12  GLU B CB    1 
ATOM   4146  C  CG    . GLU B 1 12  ? 17.072  -7.183  -25.421  1.00 86.13  ? 12  GLU B CG    1 
ATOM   4147  C  CD    . GLU B 1 12  ? 16.315  -7.559  -24.163  1.00 92.22  ? 12  GLU B CD    1 
ATOM   4148  O  OE1   . GLU B 1 12  ? 16.185  -6.692  -23.264  1.00 90.03  ? 12  GLU B OE1   1 
ATOM   4149  O  OE2   . GLU B 1 12  ? 15.871  -8.724  -24.085  1.00 91.82  ? 12  GLU B OE2   1 
ATOM   4150  N  N     . ALA B 1 13  ? 14.107  -5.555  -28.217  1.00 82.80  ? 13  ALA B N     1 
ATOM   4151  C  CA    . ALA B 1 13  ? 13.523  -5.463  -29.548  1.00 79.66  ? 13  ALA B CA    1 
ATOM   4152  C  C     . ALA B 1 13  ? 13.298  -3.998  -29.949  1.00 68.65  ? 13  ALA B C     1 
ATOM   4153  O  O     . ALA B 1 13  ? 13.610  -3.614  -31.072  1.00 66.80  ? 13  ALA B O     1 
ATOM   4154  C  CB    . ALA B 1 13  ? 12.244  -6.268  -29.597  1.00 80.08  ? 13  ALA B CB    1 
ATOM   4155  N  N     . MET B 1 14  ? 12.804  -3.176  -29.011  1.00 73.51  ? 14  MET B N     1 
ATOM   4156  C  CA    . MET B 1 14  ? 12.494  -1.773  -29.262  1.00 73.42  ? 14  MET B CA    1 
ATOM   4157  C  C     . MET B 1 14  ? 13.760  -0.982  -29.610  1.00 83.12  ? 14  MET B C     1 
ATOM   4158  O  O     . MET B 1 14  ? 13.728  -0.145  -30.507  1.00 87.86  ? 14  MET B O     1 
ATOM   4159  C  CB    . MET B 1 14  ? 11.803  -1.142  -28.049  1.00 72.60  ? 14  MET B CB    1 
ATOM   4160  C  CG    . MET B 1 14  ? 11.823  0.391   -28.034  1.00 81.16  ? 14  MET B CG    1 
ATOM   4161  S  SD    . MET B 1 14  ? 10.848  1.131   -29.385  1.00 79.41  ? 14  MET B SD    1 
ATOM   4162  C  CE    . MET B 1 14  ? 9.229   1.186   -28.618  1.00 77.58  ? 14  MET B CE    1 
ATOM   4163  N  N     . SER B 1 15  ? 14.876  -1.232  -28.911  1.00 90.18  ? 15  SER B N     1 
ATOM   4164  C  CA    . SER B 1 15  ? 16.136  -0.583  -29.255  1.00 87.29  ? 15  SER B CA    1 
ATOM   4165  C  C     . SER B 1 15  ? 16.815  -1.275  -30.443  1.00 79.42  ? 15  SER B C     1 
ATOM   4166  O  O     . SER B 1 15  ? 17.617  -0.647  -31.133  1.00 75.33  ? 15  SER B O     1 
ATOM   4167  C  CB    . SER B 1 15  ? 17.055  -0.453  -28.059  1.00 88.66  ? 15  SER B CB    1 
ATOM   4168  O  OG    . SER B 1 15  ? 16.876  -1.523  -27.147  1.00 89.20  ? 15  SER B OG    1 
ATOM   4169  N  N     . SER B 1 16  ? 16.469  -2.544  -30.710  1.00 73.54  ? 16  SER B N     1 
ATOM   4170  C  CA    . SER B 1 16  ? 16.972  -3.252  -31.883  1.00 72.29  ? 16  SER B CA    1 
ATOM   4171  C  C     . SER B 1 16  ? 16.374  -2.658  -33.159  1.00 85.78  ? 16  SER B C     1 
ATOM   4172  O  O     . SER B 1 16  ? 17.053  -2.549  -34.176  1.00 89.77  ? 16  SER B O     1 
ATOM   4173  C  CB    . SER B 1 16  ? 16.672  -4.729  -31.817  1.00 75.76  ? 16  SER B CB    1 
ATOM   4174  O  OG    . SER B 1 16  ? 16.927  -5.268  -30.527  1.00 81.35  ? 16  SER B OG    1 
ATOM   4175  N  N     . ALA B 1 17  ? 15.080  -2.310  -33.107  1.00 91.44  ? 17  ALA B N     1 
ATOM   4176  C  CA    . ALA B 1 17  ? 14.377  -1.780  -34.266  1.00 83.26  ? 17  ALA B CA    1 
ATOM   4177  C  C     . ALA B 1 17  ? 14.632  -0.279  -34.409  1.00 76.40  ? 17  ALA B C     1 
ATOM   4178  O  O     . ALA B 1 17  ? 14.729  0.210   -35.529  1.00 70.34  ? 17  ALA B O     1 
ATOM   4179  C  CB    . ALA B 1 17  ? 12.904  -2.077  -34.167  1.00 80.23  ? 17  ALA B CB    1 
ATOM   4180  N  N     . LEU B 1 18  ? 14.742  0.450   -33.286  1.00 75.85  ? 18  LEU B N     1 
ATOM   4181  C  CA    . LEU B 1 18  ? 15.112  1.860   -33.336  1.00 76.98  ? 18  LEU B CA    1 
ATOM   4182  C  C     . LEU B 1 18  ? 16.480  2.015   -33.996  1.00 78.56  ? 18  LEU B C     1 
ATOM   4183  O  O     . LEU B 1 18  ? 16.784  3.082   -34.513  1.00 84.20  ? 18  LEU B O     1 
ATOM   4184  C  CB    . LEU B 1 18  ? 15.105  2.479   -31.932  1.00 71.04  ? 18  LEU B CB    1 
ATOM   4185  C  CG    . LEU B 1 18  ? 13.741  2.900   -31.380  1.00 73.36  ? 18  LEU B CG    1 
ATOM   4186  C  CD1   . LEU B 1 18  ? 13.880  3.601   -30.036  1.00 76.34  ? 18  LEU B CD1   1 
ATOM   4187  C  CD2   . LEU B 1 18  ? 12.993  3.795   -32.352  1.00 77.73  ? 18  LEU B CD2   1 
ATOM   4188  N  N     . ASP B 1 19  ? 17.279  0.940   -33.992  1.00 94.00  ? 19  ASP B N     1 
ATOM   4189  C  CA    . ASP B 1 19  ? 18.576  0.914   -34.649  1.00 93.42  ? 19  ASP B CA    1 
ATOM   4190  C  C     . ASP B 1 19  ? 18.390  0.722   -36.152  1.00 82.84  ? 19  ASP B C     1 
ATOM   4191  O  O     . ASP B 1 19  ? 18.996  1.437   -36.946  1.00 83.08  ? 19  ASP B O     1 
ATOM   4192  C  CB    . ASP B 1 19  ? 19.464  -0.198  -34.077  1.00 101.30 ? 19  ASP B CB    1 
ATOM   4193  C  CG    . ASP B 1 19  ? 20.948  -0.001  -34.334  1.00 104.93 ? 19  ASP B CG    1 
ATOM   4194  O  OD1   . ASP B 1 19  ? 21.568  0.802   -33.605  1.00 112.03 ? 19  ASP B OD1   1 
ATOM   4195  O  OD2   . ASP B 1 19  ? 21.469  -0.634  -35.272  1.00 91.66  ? 19  ASP B OD2   1 
ATOM   4196  N  N     . ARG B 1 20  ? 17.567  -0.259  -36.541  1.00 80.09  ? 20  ARG B N     1 
ATOM   4197  C  CA    . ARG B 1 20  ? 17.391  -0.601  -37.948  1.00 80.05  ? 20  ARG B CA    1 
ATOM   4198  C  C     . ARG B 1 20  ? 16.623  0.495   -38.697  1.00 73.24  ? 20  ARG B C     1 
ATOM   4199  O  O     . ARG B 1 20  ? 16.834  0.683   -39.893  1.00 71.35  ? 20  ARG B O     1 
ATOM   4200  C  CB    . ARG B 1 20  ? 16.686  -1.951  -38.071  1.00 81.93  ? 20  ARG B CB    1 
ATOM   4201  C  CG    . ARG B 1 20  ? 17.388  -3.068  -37.314  1.00 87.57  ? 20  ARG B CG    1 
ATOM   4202  C  CD    . ARG B 1 20  ? 16.766  -4.416  -37.600  1.00 87.16  ? 20  ARG B CD    1 
ATOM   4203  N  NE    . ARG B 1 20  ? 16.955  -4.775  -38.993  1.00 79.87  ? 20  ARG B NE    1 
ATOM   4204  C  CZ    . ARG B 1 20  ? 16.177  -5.613  -39.664  1.00 93.21  ? 20  ARG B CZ    1 
ATOM   4205  N  NH1   . ARG B 1 20  ? 15.157  -6.197  -39.063  1.00 107.60 ? 20  ARG B NH1   1 
ATOM   4206  N  NH2   . ARG B 1 20  ? 16.407  -5.853  -40.942  1.00 92.46  ? 20  ARG B NH2   1 
ATOM   4207  N  N     . PHE B 1 21  ? 15.733  1.207   -37.990  1.00 71.39  ? 21  PHE B N     1 
ATOM   4208  C  CA    . PHE B 1 21  ? 15.052  2.379   -38.522  1.00 74.14  ? 21  PHE B CA    1 
ATOM   4209  C  C     . PHE B 1 21  ? 16.099  3.399   -38.970  1.00 77.79  ? 21  PHE B C     1 
ATOM   4210  O  O     . PHE B 1 21  ? 16.092  3.837   -40.125  1.00 72.02  ? 21  PHE B O     1 
ATOM   4211  C  CB    . PHE B 1 21  ? 14.092  2.980   -37.483  1.00 67.93  ? 21  PHE B CB    1 
ATOM   4212  C  CG    . PHE B 1 21  ? 12.845  2.182   -37.158  1.00 69.93  ? 21  PHE B CG    1 
ATOM   4213  C  CD1   . PHE B 1 21  ? 12.439  1.094   -37.923  1.00 68.29  ? 21  PHE B CD1   1 
ATOM   4214  C  CD2   . PHE B 1 21  ? 12.070  2.515   -36.055  1.00 72.78  ? 21  PHE B CD2   1 
ATOM   4215  C  CE1   . PHE B 1 21  ? 11.303  0.365   -37.592  1.00 68.31  ? 21  PHE B CE1   1 
ATOM   4216  C  CE2   . PHE B 1 21  ? 10.933  1.787   -35.727  1.00 67.29  ? 21  PHE B CE2   1 
ATOM   4217  C  CZ    . PHE B 1 21  ? 10.550  0.715   -36.496  1.00 62.98  ? 21  PHE B CZ    1 
ATOM   4218  N  N     . ALA B 1 22  ? 17.007  3.716   -38.036  1.00 83.43  ? 22  ALA B N     1 
ATOM   4219  C  CA    . ALA B 1 22  ? 18.122  4.634   -38.238  1.00 81.70  ? 22  ALA B CA    1 
ATOM   4220  C  C     . ALA B 1 22  ? 18.918  4.313   -39.500  1.00 71.68  ? 22  ALA B C     1 
ATOM   4221  O  O     . ALA B 1 22  ? 19.350  5.227   -40.191  1.00 83.43  ? 22  ALA B O     1 
ATOM   4222  C  CB    . ALA B 1 22  ? 19.024  4.615   -37.027  1.00 79.50  ? 22  ALA B CB    1 
ATOM   4223  N  N     . ARG B 1 23  ? 19.117  3.029   -39.805  1.00 70.89  ? 23  ARG B N     1 
ATOM   4224  C  CA    . ARG B 1 23  ? 19.824  2.645   -41.020  1.00 74.66  ? 23  ARG B CA    1 
ATOM   4225  C  C     . ARG B 1 23  ? 18.955  2.892   -42.247  1.00 81.16  ? 23  ARG B C     1 
ATOM   4226  O  O     . ARG B 1 23  ? 19.470  3.144   -43.339  1.00 80.90  ? 23  ARG B O     1 
ATOM   4227  C  CB    . ARG B 1 23  ? 20.225  1.166   -41.006  1.00 84.54  ? 23  ARG B CB    1 
ATOM   4228  C  CG    . ARG B 1 23  ? 21.224  0.799   -39.917  1.00 92.43  ? 23  ARG B CG    1 
ATOM   4229  C  CD    . ARG B 1 23  ? 21.794  -0.604  -40.032  1.00 95.17  ? 23  ARG B CD    1 
ATOM   4230  N  NE    . ARG B 1 23  ? 22.307  -1.026  -38.731  1.00 100.89 ? 23  ARG B NE    1 
ATOM   4231  C  CZ    . ARG B 1 23  ? 21.905  -2.103  -38.059  1.00 103.05 ? 23  ARG B CZ    1 
ATOM   4232  N  NH1   . ARG B 1 23  ? 21.161  -3.025  -38.646  1.00 99.86  ? 23  ARG B NH1   1 
ATOM   4233  N  NH2   . ARG B 1 23  ? 22.290  -2.280  -36.807  1.00 108.02 ? 23  ARG B NH2   1 
ATOM   4234  N  N     . ILE B 1 24  ? 17.635  2.761   -42.069  1.00 81.60  ? 24  ILE B N     1 
ATOM   4235  C  CA    . ILE B 1 24  ? 16.707  2.867   -43.178  1.00 72.39  ? 24  ILE B CA    1 
ATOM   4236  C  C     . ILE B 1 24  ? 16.632  4.319   -43.654  1.00 61.98  ? 24  ILE B C     1 
ATOM   4237  O  O     . ILE B 1 24  ? 16.642  4.566   -44.859  1.00 67.48  ? 24  ILE B O     1 
ATOM   4238  C  CB    . ILE B 1 24  ? 15.343  2.269   -42.781  1.00 73.10  ? 24  ILE B CB    1 
ATOM   4239  C  CG1   . ILE B 1 24  ? 15.404  0.738   -42.831  1.00 74.05  ? 24  ILE B CG1   1 
ATOM   4240  C  CG2   . ILE B 1 24  ? 14.226  2.817   -43.661  1.00 79.26  ? 24  ILE B CG2   1 
ATOM   4241  C  CD1   . ILE B 1 24  ? 14.357  0.039   -41.984  1.00 71.43  ? 24  ILE B CD1   1 
ATOM   4242  N  N     . VAL B 1 25  ? 16.590  5.269   -42.714  1.00 59.83  ? 25  VAL B N     1 
ATOM   4243  C  CA    . VAL B 1 25  ? 16.283  6.657   -43.040  1.00 64.85  ? 25  VAL B CA    1 
ATOM   4244  C  C     . VAL B 1 25  ? 17.492  7.538   -42.756  1.00 78.20  ? 25  VAL B C     1 
ATOM   4245  O  O     . VAL B 1 25  ? 17.728  8.513   -43.463  1.00 84.25  ? 25  VAL B O     1 
ATOM   4246  C  CB    . VAL B 1 25  ? 15.065  7.188   -42.256  1.00 63.73  ? 25  VAL B CB    1 
ATOM   4247  C  CG1   . VAL B 1 25  ? 13.787  6.463   -42.637  1.00 67.76  ? 25  VAL B CG1   1 
ATOM   4248  C  CG2   . VAL B 1 25  ? 15.271  7.143   -40.748  1.00 62.73  ? 25  VAL B CG2   1 
ATOM   4249  N  N     . GLY B 1 26  ? 18.216  7.208   -41.683  1.00 83.83  ? 26  GLY B N     1 
ATOM   4250  C  CA    . GLY B 1 26  ? 19.379  7.961   -41.268  1.00 79.11  ? 26  GLY B CA    1 
ATOM   4251  C  C     . GLY B 1 26  ? 19.195  8.420   -39.831  1.00 87.28  ? 26  GLY B C     1 
ATOM   4252  O  O     . GLY B 1 26  ? 18.158  9.000   -39.499  1.00 91.48  ? 26  GLY B O     1 
ATOM   4253  N  N     . ALA B 1 27  ? 20.221  8.164   -39.009  1.00 78.83  ? 27  ALA B N     1 
ATOM   4254  C  CA    . ALA B 1 27  ? 20.178  8.431   -37.579  1.00 76.72  ? 27  ALA B CA    1 
ATOM   4255  C  C     . ALA B 1 27  ? 19.784  9.877   -37.293  1.00 66.24  ? 27  ALA B C     1 
ATOM   4256  O  O     . ALA B 1 27  ? 19.409  10.189  -36.165  1.00 66.50  ? 27  ALA B O     1 
ATOM   4257  C  CB    . ALA B 1 27  ? 21.516  8.101   -36.952  1.00 78.63  ? 27  ALA B CB    1 
ATOM   4258  N  N     . ASP B 1 28  ? 19.864  10.762  -38.298  1.00 66.81  ? 28  ASP B N     1 
ATOM   4259  C  CA    . ASP B 1 28  ? 19.366  12.126  -38.137  1.00 74.93  ? 28  ASP B CA    1 
ATOM   4260  C  C     . ASP B 1 28  ? 17.852  12.143  -37.926  1.00 74.82  ? 28  ASP B C     1 
ATOM   4261  O  O     . ASP B 1 28  ? 17.330  13.057  -37.289  1.00 73.17  ? 28  ASP B O     1 
ATOM   4262  C  CB    . ASP B 1 28  ? 19.685  13.013  -39.344  1.00 79.58  ? 28  ASP B CB    1 
ATOM   4263  C  CG    . ASP B 1 28  ? 21.148  13.000  -39.753  1.00 88.55  ? 28  ASP B CG    1 
ATOM   4264  O  OD1   . ASP B 1 28  ? 22.020  12.989  -38.848  1.00 88.04  ? 28  ASP B OD1   1 
ATOM   4265  O  OD2   . ASP B 1 28  ? 21.407  13.012  -40.973  1.00 86.41  ? 28  ASP B OD2   1 
ATOM   4266  N  N     . TRP B 1 29  ? 17.161  11.117  -38.450  1.00 80.59  ? 29  TRP B N     1 
ATOM   4267  C  CA    . TRP B 1 29  ? 15.713  11.150  -38.608  1.00 82.66  ? 29  TRP B CA    1 
ATOM   4268  C  C     . TRP B 1 29  ? 15.013  10.122  -37.719  1.00 78.15  ? 29  TRP B C     1 
ATOM   4269  O  O     . TRP B 1 29  ? 14.078  9.464   -38.161  1.00 76.73  ? 29  TRP B O     1 
ATOM   4270  C  CB    . TRP B 1 29  ? 15.392  10.958  -40.093  1.00 76.88  ? 29  TRP B CB    1 
ATOM   4271  C  CG    . TRP B 1 29  ? 15.962  12.070  -40.918  1.00 71.57  ? 29  TRP B CG    1 
ATOM   4272  C  CD1   . TRP B 1 29  ? 16.908  11.980  -41.898  1.00 65.93  ? 29  TRP B CD1   1 
ATOM   4273  C  CD2   . TRP B 1 29  ? 15.632  13.467  -40.797  1.00 65.74  ? 29  TRP B CD2   1 
ATOM   4274  N  NE1   . TRP B 1 29  ? 17.171  13.224  -42.410  1.00 62.73  ? 29  TRP B NE1   1 
ATOM   4275  C  CE2   . TRP B 1 29  ? 16.409  14.157  -41.753  1.00 62.14  ? 29  TRP B CE2   1 
ATOM   4276  C  CE3   . TRP B 1 29  ? 14.749  14.199  -39.988  1.00 65.06  ? 29  TRP B CE3   1 
ATOM   4277  C  CZ2   . TRP B 1 29  ? 16.311  15.538  -41.929  1.00 61.13  ? 29  TRP B CZ2   1 
ATOM   4278  C  CZ3   . TRP B 1 29  ? 14.665  15.566  -40.153  1.00 64.36  ? 29  TRP B CZ3   1 
ATOM   4279  C  CH2   . TRP B 1 29  ? 15.441  16.225  -41.112  1.00 63.97  ? 29  TRP B CH2   1 
ATOM   4280  N  N     . VAL B 1 30  ? 15.482  10.011  -36.469  1.00 75.89  ? 30  VAL B N     1 
ATOM   4281  C  CA    . VAL B 1 30  ? 14.857  9.215   -35.424  1.00 72.28  ? 30  VAL B CA    1 
ATOM   4282  C  C     . VAL B 1 30  ? 14.897  10.064  -34.159  1.00 72.97  ? 30  VAL B C     1 
ATOM   4283  O  O     . VAL B 1 30  ? 15.903  10.706  -33.911  1.00 85.71  ? 30  VAL B O     1 
ATOM   4284  C  CB    . VAL B 1 30  ? 15.576  7.867   -35.235  1.00 70.67  ? 30  VAL B CB    1 
ATOM   4285  C  CG1   . VAL B 1 30  ? 14.869  6.992   -34.210  1.00 71.10  ? 30  VAL B CG1   1 
ATOM   4286  C  CG2   . VAL B 1 30  ? 15.741  7.114   -36.553  1.00 68.13  ? 30  VAL B CG2   1 
ATOM   4287  N  N     . PHE B 1 31  ? 13.812  10.112  -33.379  1.00 74.28  ? 31  PHE B N     1 
ATOM   4288  C  CA    . PHE B 1 31  ? 13.704  11.100  -32.315  1.00 76.36  ? 31  PHE B CA    1 
ATOM   4289  C  C     . PHE B 1 31  ? 13.300  10.412  -31.012  1.00 85.45  ? 31  PHE B C     1 
ATOM   4290  O  O     . PHE B 1 31  ? 12.395  9.577   -31.017  1.00 93.79  ? 31  PHE B O     1 
ATOM   4291  C  CB    . PHE B 1 31  ? 12.755  12.227  -32.745  1.00 81.68  ? 31  PHE B CB    1 
ATOM   4292  C  CG    . PHE B 1 31  ? 13.144  12.925  -34.031  1.00 85.54  ? 31  PHE B CG    1 
ATOM   4293  C  CD1   . PHE B 1 31  ? 14.392  13.518  -34.174  1.00 85.01  ? 31  PHE B CD1   1 
ATOM   4294  C  CD2   . PHE B 1 31  ? 12.270  12.989  -35.106  1.00 82.37  ? 31  PHE B CD2   1 
ATOM   4295  C  CE1   . PHE B 1 31  ? 14.755  14.151  -35.354  1.00 77.61  ? 31  PHE B CE1   1 
ATOM   4296  C  CE2   . PHE B 1 31  ? 12.635  13.626  -36.284  1.00 80.49  ? 31  PHE B CE2   1 
ATOM   4297  C  CZ    . PHE B 1 31  ? 13.876  14.205  -36.406  1.00 77.53  ? 31  PHE B CZ    1 
ATOM   4298  N  N     . THR B 1 32  ? 13.998  10.762  -29.913  1.00 80.51  ? 32  THR B N     1 
ATOM   4299  C  CA    . THR B 1 32  ? 13.797  10.162  -28.594  1.00 86.82  ? 32  THR B CA    1 
ATOM   4300  C  C     . THR B 1 32  ? 13.992  11.211  -27.486  1.00 89.77  ? 32  THR B C     1 
ATOM   4301  O  O     . THR B 1 32  ? 14.564  12.276  -27.713  1.00 91.47  ? 32  THR B O     1 
ATOM   4302  C  CB    . THR B 1 32  ? 14.706  8.934   -28.385  1.00 77.34  ? 32  THR B CB    1 
ATOM   4303  O  OG1   . THR B 1 32  ? 16.053  9.247   -28.742  1.00 76.21  ? 32  THR B OG1   1 
ATOM   4304  C  CG2   . THR B 1 32  ? 14.283  7.725   -29.191  1.00 72.78  ? 32  THR B CG2   1 
ATOM   4305  N  N     . GLU B 1 33  ? 13.477  10.916  -26.283  1.00 85.55  ? 33  GLU B N     1 
ATOM   4306  C  CA    . GLU B 1 33  ? 13.729  11.719  -25.093  1.00 92.98  ? 33  GLU B CA    1 
ATOM   4307  C  C     . GLU B 1 33  ? 13.237  13.154  -25.322  1.00 98.16  ? 33  GLU B C     1 
ATOM   4308  O  O     . GLU B 1 33  ? 12.059  13.350  -25.605  1.00 96.87  ? 33  GLU B O     1 
ATOM   4309  C  CB    . GLU B 1 33  ? 15.202  11.547  -24.713  1.00 94.71  ? 33  GLU B CB    1 
ATOM   4310  C  CG    . GLU B 1 33  ? 15.553  10.090  -24.451  1.00 99.08  ? 33  GLU B CG    1 
ATOM   4311  C  CD    . GLU B 1 33  ? 16.818  9.585   -25.123  1.00 103.51 ? 33  GLU B CD    1 
ATOM   4312  O  OE1   . GLU B 1 33  ? 16.931  8.352   -25.313  1.00 98.27  ? 33  GLU B OE1   1 
ATOM   4313  O  OE2   . GLU B 1 33  ? 17.685  10.417  -25.450  1.00 114.03 ? 33  GLU B OE2   1 
ATOM   4314  N  N     . ASP B 1 34  ? 14.114  14.162  -25.202  1.00 102.53 ? 34  ASP B N     1 
ATOM   4315  C  CA    . ASP B 1 34  ? 13.678  15.556  -25.205  1.00 103.59 ? 34  ASP B CA    1 
ATOM   4316  C  C     . ASP B 1 34  ? 13.309  16.010  -26.620  1.00 95.94  ? 34  ASP B C     1 
ATOM   4317  O  O     . ASP B 1 34  ? 12.753  17.091  -26.793  1.00 88.37  ? 34  ASP B O     1 
ATOM   4318  C  CB    . ASP B 1 34  ? 14.712  16.492  -24.558  1.00 109.59 ? 34  ASP B CB    1 
ATOM   4319  C  CG    . ASP B 1 34  ? 16.036  16.652  -25.297  1.00 109.93 ? 34  ASP B CG    1 
ATOM   4320  O  OD1   . ASP B 1 34  ? 16.037  17.213  -26.417  1.00 109.00 ? 34  ASP B OD1   1 
ATOM   4321  O  OD2   . ASP B 1 34  ? 17.068  16.241  -24.732  1.00 105.71 ? 34  ASP B OD2   1 
ATOM   4322  N  N     . LYS B 1 35  ? 13.614  15.187  -27.632  1.00 96.79  ? 35  LYS B N     1 
ATOM   4323  C  CA    . LYS B 1 35  ? 13.220  15.464  -29.005  1.00 91.35  ? 35  LYS B CA    1 
ATOM   4324  C  C     . LYS B 1 35  ? 11.790  14.982  -29.268  1.00 87.23  ? 35  LYS B C     1 
ATOM   4325  O  O     . LYS B 1 35  ? 11.359  15.005  -30.416  1.00 82.71  ? 35  LYS B O     1 
ATOM   4326  C  CB    . LYS B 1 35  ? 14.202  14.790  -29.976  1.00 94.94  ? 35  LYS B CB    1 
ATOM   4327  C  CG    . LYS B 1 35  ? 15.487  15.557  -30.275  1.00 99.19  ? 35  LYS B CG    1 
ATOM   4328  C  CD    . LYS B 1 35  ? 15.422  16.364  -31.571  1.00 105.17 ? 35  LYS B CD    1 
ATOM   4329  C  CE    . LYS B 1 35  ? 16.709  17.085  -31.916  1.00 104.44 ? 35  LYS B CE    1 
ATOM   4330  N  NZ    . LYS B 1 35  ? 17.031  18.130  -30.915  1.00 107.40 ? 35  LYS B NZ    1 
ATOM   4331  N  N     . ILE B 1 36  ? 11.050  14.575  -28.217  1.00 87.47  ? 36  ILE B N     1 
ATOM   4332  C  CA    . ILE B 1 36  ? 9.753   13.918  -28.373  1.00 84.90  ? 36  ILE B CA    1 
ATOM   4333  C  C     . ILE B 1 36  ? 8.587   14.828  -27.959  1.00 79.82  ? 36  ILE B C     1 
ATOM   4334  O  O     . ILE B 1 36  ? 7.430   14.517  -28.270  1.00 69.22  ? 36  ILE B O     1 
ATOM   4335  C  CB    . ILE B 1 36  ? 9.724   12.583  -27.593  1.00 77.91  ? 36  ILE B CB    1 
ATOM   4336  C  CG1   . ILE B 1 36  ? 8.949   11.498  -28.348  1.00 76.10  ? 36  ILE B CG1   1 
ATOM   4337  C  CG2   . ILE B 1 36  ? 9.195   12.775  -26.176  1.00 78.32  ? 36  ILE B CG2   1 
ATOM   4338  C  CD1   . ILE B 1 36  ? 9.683   10.920  -29.537  1.00 76.27  ? 36  ILE B CD1   1 
ATOM   4339  N  N     . THR B 1 37  ? 8.874   15.952  -27.279  1.00 72.15  ? 37  THR B N     1 
ATOM   4340  C  CA    . THR B 1 37  ? 7.826   16.836  -26.780  1.00 76.24  ? 37  THR B CA    1 
ATOM   4341  C  C     . THR B 1 37  ? 6.919   17.343  -27.898  1.00 68.25  ? 37  THR B C     1 
ATOM   4342  O  O     . THR B 1 37  ? 5.736   17.564  -27.661  1.00 70.76  ? 37  THR B O     1 
ATOM   4343  C  CB    . THR B 1 37  ? 8.364   18.039  -25.994  1.00 73.48  ? 37  THR B CB    1 
ATOM   4344  O  OG1   . THR B 1 37  ? 9.631   18.376  -26.557  1.00 76.04  ? 37  THR B OG1   1 
ATOM   4345  C  CG2   . THR B 1 37  ? 8.473   17.763  -24.509  1.00 73.66  ? 37  THR B CG2   1 
ATOM   4346  N  N     . PRO B 1 38  ? 7.397   17.561  -29.143  1.00 74.20  ? 38  PRO B N     1 
ATOM   4347  C  CA    . PRO B 1 38  ? 6.481   17.943  -30.220  1.00 72.92  ? 38  PRO B CA    1 
ATOM   4348  C  C     . PRO B 1 38  ? 5.369   16.912  -30.432  1.00 68.50  ? 38  PRO B C     1 
ATOM   4349  O  O     . PRO B 1 38  ? 4.268   17.280  -30.830  1.00 65.11  ? 38  PRO B O     1 
ATOM   4350  C  CB    . PRO B 1 38  ? 7.388   18.059  -31.458  1.00 71.98  ? 38  PRO B CB    1 
ATOM   4351  C  CG    . PRO B 1 38  ? 8.771   18.282  -30.887  1.00 76.90  ? 38  PRO B CG    1 
ATOM   4352  C  CD    . PRO B 1 38  ? 8.799   17.493  -29.592  1.00 74.80  ? 38  PRO B CD    1 
ATOM   4353  N  N     . TYR B 1 39  ? 5.655   15.634  -30.131  1.00 66.39  ? 39  TYR B N     1 
ATOM   4354  C  CA    . TYR B 1 39  ? 4.797   14.523  -30.508  1.00 65.19  ? 39  TYR B CA    1 
ATOM   4355  C  C     . TYR B 1 39  ? 3.799   14.190  -29.401  1.00 71.16  ? 39  TYR B C     1 
ATOM   4356  O  O     . TYR B 1 39  ? 2.967   13.295  -29.574  1.00 64.33  ? 39  TYR B O     1 
ATOM   4357  C  CB    . TYR B 1 39  ? 5.654   13.311  -30.875  1.00 67.02  ? 39  TYR B CB    1 
ATOM   4358  C  CG    . TYR B 1 39  ? 6.461   13.505  -32.134  1.00 69.66  ? 39  TYR B CG    1 
ATOM   4359  C  CD1   . TYR B 1 39  ? 5.873   13.417  -33.386  1.00 67.53  ? 39  TYR B CD1   1 
ATOM   4360  C  CD2   . TYR B 1 39  ? 7.805   13.837  -32.073  1.00 70.73  ? 39  TYR B CD2   1 
ATOM   4361  C  CE1   . TYR B 1 39  ? 6.608   13.617  -34.545  1.00 65.15  ? 39  TYR B CE1   1 
ATOM   4362  C  CE2   . TYR B 1 39  ? 8.555   14.043  -33.219  1.00 66.87  ? 39  TYR B CE2   1 
ATOM   4363  C  CZ    . TYR B 1 39  ? 7.954   13.932  -34.462  1.00 71.76  ? 39  TYR B CZ    1 
ATOM   4364  O  OH    . TYR B 1 39  ? 8.718   14.115  -35.595  1.00 67.52  ? 39  TYR B OH    1 
ATOM   4365  N  N     . GLU B 1 40  ? 3.876   14.922  -28.280  1.00 66.05  ? 40  GLU B N     1 
ATOM   4366  C  CA    . GLU B 1 40  ? 2.917   14.790  -27.193  1.00 69.53  ? 40  GLU B CA    1 
ATOM   4367  C  C     . GLU B 1 40  ? 1.631   15.514  -27.594  1.00 63.55  ? 40  GLU B C     1 
ATOM   4368  O  O     . GLU B 1 40  ? 1.673   16.423  -28.418  1.00 69.51  ? 40  GLU B O     1 
ATOM   4369  C  CB    . GLU B 1 40  ? 3.459   15.409  -25.894  1.00 72.60  ? 40  GLU B CB    1 
ATOM   4370  C  CG    . GLU B 1 40  ? 4.844   14.922  -25.476  1.00 74.00  ? 40  GLU B CG    1 
ATOM   4371  C  CD    . GLU B 1 40  ? 4.944   13.548  -24.835  1.00 70.27  ? 40  GLU B CD    1 
ATOM   4372  O  OE1   . GLU B 1 40  ? 3.898   12.956  -24.485  1.00 72.75  ? 40  GLU B OE1   1 
ATOM   4373  O  OE2   . GLU B 1 40  ? 6.082   13.067  -24.691  1.00 73.77  ? 40  GLU B OE2   1 
ATOM   4374  N  N     . ASP B 1 41  ? 0.498   15.136  -26.988  1.00 63.64  ? 41  ASP B N     1 
ATOM   4375  C  CA    . ASP B 1 41  ? -0.738  15.884  -27.156  1.00 67.99  ? 41  ASP B CA    1 
ATOM   4376  C  C     . ASP B 1 41  ? -0.521  17.308  -26.640  1.00 67.15  ? 41  ASP B C     1 
ATOM   4377  O  O     . ASP B 1 41  ? -0.272  17.493  -25.451  1.00 65.78  ? 41  ASP B O     1 
ATOM   4378  C  CB    . ASP B 1 41  ? -1.912  15.211  -26.433  1.00 64.19  ? 41  ASP B CB    1 
ATOM   4379  C  CG    . ASP B 1 41  ? -3.238  15.956  -26.564  1.00 66.78  ? 41  ASP B CG    1 
ATOM   4380  O  OD1   . ASP B 1 41  ? -3.293  16.970  -27.309  1.00 64.94  ? 41  ASP B OD1   1 
ATOM   4381  O  OD2   . ASP B 1 41  ? -4.215  15.523  -25.914  1.00 62.31  ? 41  ASP B OD2   1 
ATOM   4382  N  N     . PRO B 1 42  ? -0.613  18.361  -27.492  1.00 67.74  ? 42  PRO B N     1 
ATOM   4383  C  CA    . PRO B 1 42  ? -0.461  19.736  -27.008  1.00 65.73  ? 42  PRO B CA    1 
ATOM   4384  C  C     . PRO B 1 42  ? -1.550  20.166  -26.019  1.00 63.78  ? 42  PRO B C     1 
ATOM   4385  O  O     . PRO B 1 42  ? -1.301  21.057  -25.215  1.00 60.85  ? 42  PRO B O     1 
ATOM   4386  C  CB    . PRO B 1 42  ? -0.474  20.604  -28.283  1.00 63.89  ? 42  PRO B CB    1 
ATOM   4387  C  CG    . PRO B 1 42  ? -1.166  19.743  -29.329  1.00 65.23  ? 42  PRO B CG    1 
ATOM   4388  C  CD    . PRO B 1 42  ? -0.879  18.303  -28.943  1.00 65.50  ? 42  PRO B CD    1 
ATOM   4389  N  N     . TYR B 1 43  ? -2.750  19.553  -26.078  1.00 60.62  ? 43  TYR B N     1 
ATOM   4390  C  CA    . TYR B 1 43  ? -3.862  19.927  -25.201  1.00 68.36  ? 43  TYR B CA    1 
ATOM   4391  C  C     . TYR B 1 43  ? -4.193  18.777  -24.239  1.00 63.84  ? 43  TYR B C     1 
ATOM   4392  O  O     . TYR B 1 43  ? -5.275  18.193  -24.302  1.00 63.01  ? 43  TYR B O     1 
ATOM   4393  C  CB    . TYR B 1 43  ? -5.106  20.351  -26.004  1.00 62.70  ? 43  TYR B CB    1 
ATOM   4394  C  CG    . TYR B 1 43  ? -4.865  21.362  -27.099  1.00 61.76  ? 43  TYR B CG    1 
ATOM   4395  C  CD1   . TYR B 1 43  ? -3.829  22.289  -27.032  1.00 58.34  ? 43  TYR B CD1   1 
ATOM   4396  C  CD2   . TYR B 1 43  ? -5.650  21.359  -28.241  1.00 59.25  ? 43  TYR B CD2   1 
ATOM   4397  C  CE1   . TYR B 1 43  ? -3.596  23.201  -28.053  1.00 59.84  ? 43  TYR B CE1   1 
ATOM   4398  C  CE2   . TYR B 1 43  ? -5.427  22.256  -29.275  1.00 64.41  ? 43  TYR B CE2   1 
ATOM   4399  C  CZ    . TYR B 1 43  ? -4.394  23.177  -29.186  1.00 68.79  ? 43  TYR B CZ    1 
ATOM   4400  O  OH    . TYR B 1 43  ? -4.173  24.059  -30.225  1.00 63.82  ? 43  TYR B OH    1 
ATOM   4401  N  N     . THR B 1 44  ? -3.253  18.490  -23.328  1.00 59.55  ? 44  THR B N     1 
ATOM   4402  C  CA    . THR B 1 44  ? -3.375  17.418  -22.351  1.00 57.42  ? 44  THR B CA    1 
ATOM   4403  C  C     . THR B 1 44  ? -4.754  17.439  -21.693  1.00 52.38  ? 44  THR B C     1 
ATOM   4404  O  O     . THR B 1 44  ? -5.220  18.488  -21.267  1.00 58.02  ? 44  THR B O     1 
ATOM   4405  C  CB    . THR B 1 44  ? -2.292  17.543  -21.269  1.00 57.05  ? 44  THR B CB    1 
ATOM   4406  O  OG1   . THR B 1 44  ? -1.115  18.062  -21.886  1.00 55.03  ? 44  THR B OG1   1 
ATOM   4407  C  CG2   . THR B 1 44  ? -1.982  16.230  -20.575  1.00 55.57  ? 44  THR B CG2   1 
ATOM   4408  N  N     . ILE B 1 45  ? -5.383  16.265  -21.619  1.00 57.98  ? 45  ILE B N     1 
ATOM   4409  C  CA    . ILE B 1 45  ? -6.654  16.072  -20.932  1.00 62.73  ? 45  ILE B CA    1 
ATOM   4410  C  C     . ILE B 1 45  ? -6.431  15.157  -19.728  1.00 62.77  ? 45  ILE B C     1 
ATOM   4411  O  O     . ILE B 1 45  ? -7.011  15.364  -18.667  1.00 60.83  ? 45  ILE B O     1 
ATOM   4412  C  CB    . ILE B 1 45  ? -7.719  15.469  -21.875  1.00 60.17  ? 45  ILE B CB    1 
ATOM   4413  C  CG1   . ILE B 1 45  ? -8.075  16.402  -23.041  1.00 61.99  ? 45  ILE B CG1   1 
ATOM   4414  C  CG2   . ILE B 1 45  ? -8.952  15.059  -21.072  1.00 60.10  ? 45  ILE B CG2   1 
ATOM   4415  C  CD1   . ILE B 1 45  ? -8.823  15.725  -24.162  1.00 60.84  ? 45  ILE B CD1   1 
ATOM   4416  N  N     . SER B 1 46  ? -5.637  14.102  -19.931  1.00 63.52  ? 46  SER B N     1 
ATOM   4417  C  CA    . SER B 1 46  ? -5.373  13.125  -18.886  1.00 64.49  ? 46  SER B CA    1 
ATOM   4418  C  C     . SER B 1 46  ? -4.418  13.692  -17.844  1.00 66.90  ? 46  SER B C     1 
ATOM   4419  O  O     . SER B 1 46  ? -3.469  14.388  -18.201  1.00 66.49  ? 46  SER B O     1 
ATOM   4420  C  CB    . SER B 1 46  ? -4.783  11.875  -19.461  1.00 69.65  ? 46  SER B CB    1 
ATOM   4421  O  OG    . SER B 1 46  ? -4.462  10.964  -18.425  1.00 66.40  ? 46  SER B OG    1 
ATOM   4422  N  N     . ASN B 1 47  ? -4.652  13.311  -16.578  1.00 63.52  ? 47  ASN B N     1 
ATOM   4423  C  CA    . ASN B 1 47  ? -3.781  13.630  -15.455  1.00 67.12  ? 47  ASN B CA    1 
ATOM   4424  C  C     . ASN B 1 47  ? -2.818  12.477  -15.147  1.00 71.53  ? 47  ASN B C     1 
ATOM   4425  O  O     . ASN B 1 47  ? -1.879  12.645  -14.370  1.00 83.06  ? 47  ASN B O     1 
ATOM   4426  C  CB    . ASN B 1 47  ? -4.608  14.003  -14.220  1.00 67.13  ? 47  ASN B CB    1 
ATOM   4427  C  CG    . ASN B 1 47  ? -5.210  15.387  -14.337  1.00 67.92  ? 47  ASN B CG    1 
ATOM   4428  O  OD1   . ASN B 1 47  ? -4.527  16.327  -14.733  1.00 70.30  ? 47  ASN B OD1   1 
ATOM   4429  N  ND2   . ASN B 1 47  ? -6.488  15.522  -14.036  1.00 68.19  ? 47  ASN B ND2   1 
ATOM   4430  N  N     . ASP B 1 48  ? -3.056  11.304  -15.745  1.00 71.29  ? 48  ASP B N     1 
ATOM   4431  C  CA    . ASP B 1 48  ? -2.128  10.184  -15.680  1.00 72.28  ? 48  ASP B CA    1 
ATOM   4432  C  C     . ASP B 1 48  ? -1.077  10.380  -16.775  1.00 71.76  ? 48  ASP B C     1 
ATOM   4433  O  O     . ASP B 1 48  ? -1.380  10.210  -17.955  1.00 60.05  ? 48  ASP B O     1 
ATOM   4434  C  CB    . ASP B 1 48  ? -2.897  8.857   -15.785  1.00 77.00  ? 48  ASP B CB    1 
ATOM   4435  C  CG    . ASP B 1 48  ? -2.073  7.576   -15.854  1.00 76.71  ? 48  ASP B CG    1 
ATOM   4436  O  OD1   . ASP B 1 48  ? -0.853  7.655   -16.103  1.00 80.74  ? 48  ASP B OD1   1 
ATOM   4437  O  OD2   . ASP B 1 48  ? -2.668  6.494   -15.658  1.00 78.44  ? 48  ASP B OD2   1 
ATOM   4438  N  N     . GLU B 1 49  ? 0.165   10.688  -16.365  1.00 70.06  ? 49  GLU B N     1 
ATOM   4439  C  CA    . GLU B 1 49  ? 1.238   11.085  -17.267  1.00 76.23  ? 49  GLU B CA    1 
ATOM   4440  C  C     . GLU B 1 49  ? 1.827   9.893   -18.028  1.00 70.23  ? 49  GLU B C     1 
ATOM   4441  O  O     . GLU B 1 49  ? 2.754   10.089  -18.805  1.00 65.44  ? 49  GLU B O     1 
ATOM   4442  C  CB    . GLU B 1 49  ? 2.369   11.769  -16.491  1.00 83.42  ? 49  GLU B CB    1 
ATOM   4443  C  CG    . GLU B 1 49  ? 1.941   13.011  -15.725  1.00 92.88  ? 49  GLU B CG    1 
ATOM   4444  C  CD    . GLU B 1 49  ? 2.898   13.431  -14.619  1.00 94.30  ? 49  GLU B CD    1 
ATOM   4445  O  OE1   . GLU B 1 49  ? 3.643   14.397  -14.844  1.00 99.72  ? 49  GLU B OE1   1 
ATOM   4446  O  OE2   . GLU B 1 49  ? 2.888   12.801  -13.530  1.00 88.99  ? 49  GLU B OE2   1 
ATOM   4447  N  N     . THR B 1 50  ? 1.312   8.671   -17.817  1.00 68.53  ? 50  THR B N     1 
ATOM   4448  C  CA    . THR B 1 50  ? 1.789   7.497   -18.544  1.00 67.48  ? 50  THR B CA    1 
ATOM   4449  C  C     . THR B 1 50  ? 0.940   7.192   -19.791  1.00 66.04  ? 50  THR B C     1 
ATOM   4450  O  O     . THR B 1 50  ? 1.309   6.304   -20.548  1.00 64.69  ? 50  THR B O     1 
ATOM   4451  C  CB    . THR B 1 50  ? 1.823   6.266   -17.628  1.00 64.18  ? 50  THR B CB    1 
ATOM   4452  O  OG1   . THR B 1 50  ? 0.474   5.930   -17.303  1.00 68.31  ? 50  THR B OG1   1 
ATOM   4453  C  CG2   . THR B 1 50  ? 2.611   6.473   -16.350  1.00 62.23  ? 50  THR B CG2   1 
ATOM   4454  N  N     . GLU B 1 51  ? -0.165  7.928   -20.026  1.00 66.43  ? 51  GLU B N     1 
ATOM   4455  C  CA    . GLU B 1 51  ? -1.102  7.656   -21.117  1.00 70.59  ? 51  GLU B CA    1 
ATOM   4456  C  C     . GLU B 1 51  ? -0.814  8.515   -22.350  1.00 70.15  ? 51  GLU B C     1 
ATOM   4457  O  O     . GLU B 1 51  ? -0.397  9.664   -22.206  1.00 61.90  ? 51  GLU B O     1 
ATOM   4458  C  CB    . GLU B 1 51  ? -2.536  7.992   -20.707  1.00 71.90  ? 51  GLU B CB    1 
ATOM   4459  C  CG    . GLU B 1 51  ? -3.045  7.196   -19.526  1.00 72.99  ? 51  GLU B CG    1 
ATOM   4460  C  CD    . GLU B 1 51  ? -4.522  7.422   -19.261  1.00 71.51  ? 51  GLU B CD    1 
ATOM   4461  O  OE1   . GLU B 1 51  ? -4.888  8.526   -18.823  1.00 72.05  ? 51  GLU B OE1   1 
ATOM   4462  O  OE2   . GLU B 1 51  ? -5.304  6.515   -19.550  1.00 77.04  ? 51  GLU B OE2   1 
ATOM   4463  N  N     . HIS B 1 52  ? -1.093  7.966   -23.549  1.00 68.51  ? 52  HIS B N     1 
ATOM   4464  C  CA    . HIS B 1 52  ? -0.873  8.651   -24.822  1.00 63.59  ? 52  HIS B CA    1 
ATOM   4465  C  C     . HIS B 1 52  ? 0.546   9.209   -24.959  1.00 61.88  ? 52  HIS B C     1 
ATOM   4466  O  O     . HIS B 1 52  ? 0.718   10.359  -25.377  1.00 65.33  ? 52  HIS B O     1 
ATOM   4467  C  CB    . HIS B 1 52  ? -1.851  9.818   -24.980  1.00 62.64  ? 52  HIS B CB    1 
ATOM   4468  C  CG    . HIS B 1 52  ? -3.225  9.429   -24.600  1.00 66.68  ? 52  HIS B CG    1 
ATOM   4469  N  ND1   . HIS B 1 52  ? -3.784  8.251   -25.038  1.00 73.32  ? 52  HIS B ND1   1 
ATOM   4470  C  CD2   . HIS B 1 52  ? -4.127  10.011  -23.809  1.00 70.80  ? 52  HIS B CD2   1 
ATOM   4471  C  CE1   . HIS B 1 52  ? -5.006  8.147   -24.537  1.00 73.88  ? 52  HIS B CE1   1 
ATOM   4472  N  NE2   . HIS B 1 52  ? -5.234  9.204   -23.788  1.00 74.90  ? 52  HIS B NE2   1 
ATOM   4473  N  N     . ARG B 1 53  ? 1.550   8.381   -24.631  1.00 61.91  ? 53  ARG B N     1 
ATOM   4474  C  CA    . ARG B 1 53  ? 2.957   8.775   -24.602  1.00 66.39  ? 53  ARG B CA    1 
ATOM   4475  C  C     . ARG B 1 53  ? 3.710   8.086   -25.740  1.00 64.35  ? 53  ARG B C     1 
ATOM   4476  O  O     . ARG B 1 53  ? 3.871   6.865   -25.739  1.00 70.74  ? 53  ARG B O     1 
ATOM   4477  C  CB    . ARG B 1 53  ? 3.625   8.393   -23.271  1.00 63.01  ? 53  ARG B CB    1 
ATOM   4478  C  CG    . ARG B 1 53  ? 2.880   8.859   -22.028  1.00 64.24  ? 53  ARG B CG    1 
ATOM   4479  C  CD    . ARG B 1 53  ? 2.630   10.357  -21.998  1.00 69.38  ? 53  ARG B CD    1 
ATOM   4480  N  NE    . ARG B 1 53  ? 3.832   11.158  -22.202  1.00 77.45  ? 53  ARG B NE    1 
ATOM   4481  C  CZ    . ARG B 1 53  ? 4.826   11.294  -21.325  1.00 87.18  ? 53  ARG B CZ    1 
ATOM   4482  N  NH1   . ARG B 1 53  ? 4.747   10.755  -20.119  1.00 85.68  ? 53  ARG B NH1   1 
ATOM   4483  N  NH2   . ARG B 1 53  ? 5.904   11.985  -21.656  1.00 85.03  ? 53  ARG B NH2   1 
ATOM   4484  N  N     . PRO B 1 54  ? 4.188   8.829   -26.763  1.00 64.58  ? 54  PRO B N     1 
ATOM   4485  C  CA    . PRO B 1 54  ? 4.986   8.209   -27.817  1.00 61.79  ? 54  PRO B CA    1 
ATOM   4486  C  C     . PRO B 1 54  ? 6.317   7.760   -27.234  1.00 62.02  ? 54  PRO B C     1 
ATOM   4487  O  O     . PRO B 1 54  ? 6.829   8.378   -26.311  1.00 67.93  ? 54  PRO B O     1 
ATOM   4488  C  CB    . PRO B 1 54  ? 5.163   9.303   -28.875  1.00 61.02  ? 54  PRO B CB    1 
ATOM   4489  C  CG    . PRO B 1 54  ? 4.887   10.610  -28.137  1.00 62.65  ? 54  PRO B CG    1 
ATOM   4490  C  CD    . PRO B 1 54  ? 3.981   10.272  -26.970  1.00 60.72  ? 54  PRO B CD    1 
ATOM   4491  N  N     . TYR B 1 55  ? 6.856   6.664   -27.765  1.00 68.06  ? 55  TYR B N     1 
ATOM   4492  C  CA    . TYR B 1 55  ? 8.179   6.220   -27.368  1.00 68.13  ? 55  TYR B CA    1 
ATOM   4493  C  C     . TYR B 1 55  ? 9.256   6.939   -28.167  1.00 72.59  ? 55  TYR B C     1 
ATOM   4494  O  O     . TYR B 1 55  ? 10.244  7.386   -27.599  1.00 78.07  ? 55  TYR B O     1 
ATOM   4495  C  CB    . TYR B 1 55  ? 8.375   4.722   -27.591  1.00 66.29  ? 55  TYR B CB    1 
ATOM   4496  C  CG    . TYR B 1 55  ? 9.492   4.164   -26.752  1.00 74.94  ? 55  TYR B CG    1 
ATOM   4497  C  CD1   . TYR B 1 55  ? 9.328   3.991   -25.383  1.00 75.38  ? 55  TYR B CD1   1 
ATOM   4498  C  CD2   . TYR B 1 55  ? 10.728  3.873   -27.307  1.00 76.28  ? 55  TYR B CD2   1 
ATOM   4499  C  CE1   . TYR B 1 55  ? 10.348  3.491   -24.593  1.00 76.13  ? 55  TYR B CE1   1 
ATOM   4500  C  CE2   . TYR B 1 55  ? 11.763  3.379   -26.530  1.00 79.33  ? 55  TYR B CE2   1 
ATOM   4501  C  CZ    . TYR B 1 55  ? 11.569  3.191   -25.172  1.00 80.62  ? 55  TYR B CZ    1 
ATOM   4502  O  OH    . TYR B 1 55  ? 12.582  2.694   -24.401  1.00 81.96  ? 55  TYR B OH    1 
ATOM   4503  N  N     . ALA B 1 56  ? 9.085   6.973   -29.494  1.00 73.84  ? 56  ALA B N     1 
ATOM   4504  C  CA    . ALA B 1 56  ? 10.082  7.510   -30.405  1.00 67.08  ? 56  ALA B CA    1 
ATOM   4505  C  C     . ALA B 1 56  ? 9.366   8.052   -31.631  1.00 71.94  ? 56  ALA B C     1 
ATOM   4506  O  O     . ALA B 1 56  ? 8.141   8.091   -31.649  1.00 71.88  ? 56  ALA B O     1 
ATOM   4507  C  CB    . ALA B 1 56  ? 11.064  6.436   -30.790  1.00 63.71  ? 56  ALA B CB    1 
ATOM   4508  N  N     . ALA B 1 57  ? 10.142  8.458   -32.642  1.00 71.18  ? 57  ALA B N     1 
ATOM   4509  C  CA    . ALA B 1 57  ? 9.588   8.893   -33.913  1.00 68.81  ? 57  ALA B CA    1 
ATOM   4510  C  C     . ALA B 1 57  ? 10.614  8.645   -35.011  1.00 64.73  ? 57  ALA B C     1 
ATOM   4511  O  O     . ALA B 1 57  ? 11.785  8.947   -34.823  1.00 69.81  ? 57  ALA B O     1 
ATOM   4512  C  CB    . ALA B 1 57  ? 9.189   10.348  -33.833  1.00 64.89  ? 57  ALA B CB    1 
ATOM   4513  N  N     . VAL B 1 58  ? 10.174  8.048   -36.126  1.00 61.49  ? 58  VAL B N     1 
ATOM   4514  C  CA    . VAL B 1 58  ? 11.001  7.889   -37.315  1.00 57.71  ? 58  VAL B CA    1 
ATOM   4515  C  C     . VAL B 1 58  ? 10.369  8.726   -38.426  1.00 65.31  ? 58  VAL B C     1 
ATOM   4516  O  O     . VAL B 1 58  ? 9.148   8.898   -38.460  1.00 66.12  ? 58  VAL B O     1 
ATOM   4517  C  CB    . VAL B 1 58  ? 11.169  6.403   -37.689  1.00 62.97  ? 58  VAL B CB    1 
ATOM   4518  C  CG1   . VAL B 1 58  ? 9.838   5.699   -37.894  1.00 72.25  ? 58  VAL B CG1   1 
ATOM   4519  C  CG2   . VAL B 1 58  ? 12.054  6.196   -38.905  1.00 63.14  ? 58  VAL B CG2   1 
ATOM   4520  N  N     . ALA B 1 59  ? 11.204  9.288   -39.311  1.00 62.91  ? 59  ALA B N     1 
ATOM   4521  C  CA    . ALA B 1 59  ? 10.735  10.275  -40.270  1.00 56.66  ? 59  ALA B CA    1 
ATOM   4522  C  C     . ALA B 1 59  ? 11.317  9.966   -41.638  1.00 60.11  ? 59  ALA B C     1 
ATOM   4523  O  O     . ALA B 1 59  ? 12.380  10.473  -41.990  1.00 64.49  ? 59  ALA B O     1 
ATOM   4524  C  CB    . ALA B 1 59  ? 11.091  11.663  -39.815  1.00 54.53  ? 59  ALA B CB    1 
ATOM   4525  N  N     . PRO B 1 60  ? 10.641  9.112   -42.440  1.00 59.60  ? 60  PRO B N     1 
ATOM   4526  C  CA    . PRO B 1 60  ? 11.107  8.788   -43.785  1.00 53.38  ? 60  PRO B CA    1 
ATOM   4527  C  C     . PRO B 1 60  ? 10.904  9.913   -44.797  1.00 60.15  ? 60  PRO B C     1 
ATOM   4528  O  O     . PRO B 1 60  ? 10.229  10.909  -44.509  1.00 50.85  ? 60  PRO B O     1 
ATOM   4529  C  CB    . PRO B 1 60  ? 10.254  7.575   -44.178  1.00 58.53  ? 60  PRO B CB    1 
ATOM   4530  C  CG    . PRO B 1 60  ? 8.974   7.756   -43.393  1.00 56.54  ? 60  PRO B CG    1 
ATOM   4531  C  CD    . PRO B 1 60  ? 9.397   8.400   -42.089  1.00 60.41  ? 60  PRO B CD    1 
ATOM   4532  N  N     . ALA B 1 61  ? 11.530  9.723   -45.969  1.00 58.73  ? 61  ALA B N     1 
ATOM   4533  C  CA    . ALA B 1 61  ? 11.472  10.674  -47.065  1.00 60.04  ? 61  ALA B CA    1 
ATOM   4534  C  C     . ALA B 1 61  ? 10.962  9.996   -48.330  1.00 52.65  ? 61  ALA B C     1 
ATOM   4535  O  O     . ALA B 1 61  ? 10.858  10.629  -49.373  1.00 58.77  ? 61  ALA B O     1 
ATOM   4536  C  CB    . ALA B 1 61  ? 12.841  11.279  -47.286  1.00 61.50  ? 61  ALA B CB    1 
ATOM   4537  N  N     . SER B 1 62  ? 10.638  8.706   -48.258  1.00 55.05  ? 62  SER B N     1 
ATOM   4538  C  CA    . SER B 1 62  ? 10.205  8.004   -49.448  1.00 54.77  ? 62  SER B CA    1 
ATOM   4539  C  C     . SER B 1 62  ? 9.278   6.853   -49.076  1.00 56.97  ? 62  SER B C     1 
ATOM   4540  O  O     . SER B 1 62  ? 9.307   6.327   -47.962  1.00 51.40  ? 62  SER B O     1 
ATOM   4541  C  CB    . SER B 1 62  ? 11.390  7.505   -50.226  1.00 56.23  ? 62  SER B CB    1 
ATOM   4542  O  OG    . SER B 1 62  ? 11.763  6.206   -49.781  1.00 58.61  ? 62  SER B OG    1 
ATOM   4543  N  N     . THR B 1 63  ? 8.496   6.430   -50.062  1.00 54.12  ? 63  THR B N     1 
ATOM   4544  C  CA    . THR B 1 63  ? 7.623   5.285   -49.906  1.00 59.97  ? 63  THR B CA    1 
ATOM   4545  C  C     . THR B 1 63  ? 8.444   4.021   -49.671  1.00 64.36  ? 63  THR B C     1 
ATOM   4546  O  O     . THR B 1 63  ? 8.002   3.172   -48.896  1.00 55.89  ? 63  THR B O     1 
ATOM   4547  C  CB    . THR B 1 63  ? 6.698   5.165   -51.116  1.00 57.49  ? 63  THR B CB    1 
ATOM   4548  O  OG1   . THR B 1 63  ? 5.888   6.342   -51.050  1.00 58.51  ? 63  THR B OG1   1 
ATOM   4549  C  CG2   . THR B 1 63  ? 5.881   3.893   -51.115  1.00 55.85  ? 63  THR B CG2   1 
ATOM   4550  N  N     . GLU B 1 64  ? 9.612   3.907   -50.336  1.00 67.43  ? 64  GLU B N     1 
ATOM   4551  C  CA    . GLU B 1 64  ? 10.472  2.733   -50.207  1.00 68.20  ? 64  GLU B CA    1 
ATOM   4552  C  C     . GLU B 1 64  ? 10.867  2.576   -48.737  1.00 58.94  ? 64  GLU B C     1 
ATOM   4553  O  O     . GLU B 1 64  ? 10.876  1.465   -48.226  1.00 56.08  ? 64  GLU B O     1 
ATOM   4554  C  CB    . GLU B 1 64  ? 11.713  2.793   -51.119  1.00 74.32  ? 64  GLU B CB    1 
ATOM   4555  C  CG    . GLU B 1 64  ? 12.517  1.477   -51.168  1.00 87.81  ? 64  GLU B CG    1 
ATOM   4556  C  CD    . GLU B 1 64  ? 13.999  1.493   -51.566  1.00 95.46  ? 64  GLU B CD    1 
ATOM   4557  O  OE1   . GLU B 1 64  ? 14.318  1.463   -52.792  1.00 85.18  ? 64  GLU B OE1   1 
ATOM   4558  O  OE2   . GLU B 1 64  ? 14.859  1.489   -50.646  1.00 86.62  ? 64  GLU B OE2   1 
ATOM   4559  N  N     . GLU B 1 65  ? 11.162  3.695   -48.060  1.00 57.08  ? 65  GLU B N     1 
ATOM   4560  C  CA    . GLU B 1 65  ? 11.588  3.691   -46.667  1.00 53.75  ? 65  GLU B CA    1 
ATOM   4561  C  C     . GLU B 1 65  ? 10.435  3.309   -45.742  1.00 59.79  ? 65  GLU B C     1 
ATOM   4562  O  O     . GLU B 1 65  ? 10.615  2.570   -44.766  1.00 58.84  ? 65  GLU B O     1 
ATOM   4563  C  CB    . GLU B 1 65  ? 12.144  5.064   -46.278  1.00 55.48  ? 65  GLU B CB    1 
ATOM   4564  C  CG    . GLU B 1 65  ? 13.610  5.242   -46.654  1.00 62.48  ? 65  GLU B CG    1 
ATOM   4565  C  CD    . GLU B 1 65  ? 14.125  6.670   -46.772  1.00 63.33  ? 65  GLU B CD    1 
ATOM   4566  O  OE1   . GLU B 1 65  ? 13.796  7.510   -45.905  1.00 58.93  ? 65  GLU B OE1   1 
ATOM   4567  O  OE2   . GLU B 1 65  ? 14.885  6.928   -47.731  1.00 72.07  ? 65  GLU B OE2   1 
ATOM   4568  N  N     . VAL B 1 66  ? 9.246   3.837   -46.041  1.00 50.19  ? 66  VAL B N     1 
ATOM   4569  C  CA    . VAL B 1 66  ? 8.070   3.481   -45.271  1.00 47.66  ? 66  VAL B CA    1 
ATOM   4570  C  C     . VAL B 1 66  ? 7.920   1.963   -45.309  1.00 45.90  ? 66  VAL B C     1 
ATOM   4571  O  O     . VAL B 1 66  ? 7.671   1.337   -44.280  1.00 51.87  ? 66  VAL B O     1 
ATOM   4572  C  CB    . VAL B 1 66  ? 6.802   4.176   -45.806  1.00 44.76  ? 66  VAL B CB    1 
ATOM   4573  C  CG1   . VAL B 1 66  ? 5.552   3.677   -45.085  1.00 46.55  ? 66  VAL B CG1   1 
ATOM   4574  C  CG2   . VAL B 1 66  ? 6.906   5.686   -45.706  1.00 47.51  ? 66  VAL B CG2   1 
ATOM   4575  N  N     . GLN B 1 67  ? 8.091   1.390   -46.504  1.00 44.75  ? 67  GLN B N     1 
ATOM   4576  C  CA    . GLN B 1 67  ? 7.944   -0.038  -46.691  1.00 48.40  ? 67  GLN B CA    1 
ATOM   4577  C  C     . GLN B 1 67  ? 8.878   -0.771  -45.738  1.00 56.32  ? 67  GLN B C     1 
ATOM   4578  O  O     . GLN B 1 67  ? 8.464   -1.757  -45.129  1.00 59.39  ? 67  GLN B O     1 
ATOM   4579  C  CB    . GLN B 1 67  ? 8.194   -0.455  -48.137  1.00 49.05  ? 67  GLN B CB    1 
ATOM   4580  C  CG    . GLN B 1 67  ? 7.208   0.132   -49.140  1.00 54.02  ? 67  GLN B CG    1 
ATOM   4581  C  CD    . GLN B 1 67  ? 7.329   -0.473  -50.521  1.00 51.57  ? 67  GLN B CD    1 
ATOM   4582  O  OE1   . GLN B 1 67  ? 7.773   0.168   -51.470  1.00 57.52  ? 67  GLN B OE1   1 
ATOM   4583  N  NE2   . GLN B 1 67  ? 6.912   -1.718  -50.657  1.00 57.24  ? 67  GLN B NE2   1 
ATOM   4584  N  N     . GLU B 1 68  ? 10.119  -0.268  -45.602  1.00 65.38  ? 68  GLU B N     1 
ATOM   4585  C  CA    . GLU B 1 68  ? 11.159  -0.945  -44.836  1.00 66.72  ? 68  GLU B CA    1 
ATOM   4586  C  C     . GLU B 1 68  ? 10.867  -0.840  -43.344  1.00 59.78  ? 68  GLU B C     1 
ATOM   4587  O  O     . GLU B 1 68  ? 10.971  -1.813  -42.603  1.00 66.03  ? 68  GLU B O     1 
ATOM   4588  C  CB    . GLU B 1 68  ? 12.537  -0.325  -45.090  1.00 77.98  ? 68  GLU B CB    1 
ATOM   4589  C  CG    . GLU B 1 68  ? 13.002  -0.369  -46.533  1.00 86.56  ? 68  GLU B CG    1 
ATOM   4590  C  CD    . GLU B 1 68  ? 13.321  -1.751  -47.069  1.00 104.01 ? 68  GLU B CD    1 
ATOM   4591  O  OE1   . GLU B 1 68  ? 12.981  -2.750  -46.392  1.00 98.23  ? 68  GLU B OE1   1 
ATOM   4592  O  OE2   . GLU B 1 68  ? 13.934  -1.819  -48.159  1.00 131.38 ? 68  GLU B OE2   1 
ATOM   4593  N  N     . ILE B 1 69  ? 10.558  0.376   -42.906  1.00 56.20  ? 69  ILE B N     1 
ATOM   4594  C  CA    . ILE B 1 69  ? 10.157  0.626   -41.535  1.00 63.31  ? 69  ILE B CA    1 
ATOM   4595  C  C     . ILE B 1 69  ? 9.089   -0.395  -41.122  1.00 64.12  ? 69  ILE B C     1 
ATOM   4596  O  O     . ILE B 1 69  ? 9.195   -1.021  -40.072  1.00 66.21  ? 69  ILE B O     1 
ATOM   4597  C  CB    . ILE B 1 69  ? 9.676   2.085   -41.398  1.00 59.50  ? 69  ILE B CB    1 
ATOM   4598  C  CG1   . ILE B 1 69  ? 10.831  3.079   -41.591  1.00 61.78  ? 69  ILE B CG1   1 
ATOM   4599  C  CG2   . ILE B 1 69  ? 8.967   2.281   -40.072  1.00 60.66  ? 69  ILE B CG2   1 
ATOM   4600  C  CD1   . ILE B 1 69  ? 10.430  4.542   -41.591  1.00 57.30  ? 69  ILE B CD1   1 
ATOM   4601  N  N     . VAL B 1 70  ? 8.077   -0.575  -41.975  1.00 60.10  ? 70  VAL B N     1 
ATOM   4602  C  CA    . VAL B 1 70  ? 6.943   -1.434  -41.672  1.00 59.87  ? 70  VAL B CA    1 
ATOM   4603  C  C     . VAL B 1 70  ? 7.416   -2.885  -41.616  1.00 56.12  ? 70  VAL B C     1 
ATOM   4604  O  O     . VAL B 1 70  ? 6.923   -3.663  -40.805  1.00 51.57  ? 70  VAL B O     1 
ATOM   4605  C  CB    . VAL B 1 70  ? 5.803   -1.239  -42.701  1.00 54.45  ? 70  VAL B CB    1 
ATOM   4606  C  CG1   . VAL B 1 70  ? 4.737   -2.325  -42.622  1.00 52.24  ? 70  VAL B CG1   1 
ATOM   4607  C  CG2   . VAL B 1 70  ? 5.163   0.136   -42.569  1.00 56.52  ? 70  VAL B CG2   1 
ATOM   4608  N  N     . ARG B 1 71  ? 8.338   -3.255  -42.506  1.00 55.80  ? 71  ARG B N     1 
ATOM   4609  C  CA    . ARG B 1 71  ? 8.846   -4.620  -42.530  1.00 61.77  ? 71  ARG B CA    1 
ATOM   4610  C  C     . ARG B 1 71  ? 9.560   -4.927  -41.219  1.00 58.28  ? 71  ARG B C     1 
ATOM   4611  O  O     . ARG B 1 71  ? 9.407   -6.013  -40.666  1.00 61.92  ? 71  ARG B O     1 
ATOM   4612  C  CB    . ARG B 1 71  ? 9.783   -4.839  -43.713  1.00 55.84  ? 71  ARG B CB    1 
ATOM   4613  C  CG    . ARG B 1 71  ? 9.033   -5.092  -45.005  1.00 62.17  ? 71  ARG B CG    1 
ATOM   4614  C  CD    . ARG B 1 71  ? 9.978   -5.042  -46.185  1.00 62.52  ? 71  ARG B CD    1 
ATOM   4615  N  NE    . ARG B 1 71  ? 9.252   -5.250  -47.425  1.00 62.49  ? 71  ARG B NE    1 
ATOM   4616  C  CZ    . ARG B 1 71  ? 9.344   -4.477  -48.500  1.00 66.71  ? 71  ARG B CZ    1 
ATOM   4617  N  NH1   . ARG B 1 71  ? 10.231  -3.498  -48.543  1.00 71.33  ? 71  ARG B NH1   1 
ATOM   4618  N  NH2   . ARG B 1 71  ? 8.571   -4.710  -49.544  1.00 61.87  ? 71  ARG B NH2   1 
ATOM   4619  N  N     . VAL B 1 72  ? 10.309  -3.942  -40.729  1.00 54.37  ? 72  VAL B N     1 
ATOM   4620  C  CA    . VAL B 1 72  ? 11.069  -4.084  -39.502  1.00 60.70  ? 72  VAL B CA    1 
ATOM   4621  C  C     . VAL B 1 72  ? 10.130  -4.067  -38.299  1.00 67.70  ? 72  VAL B C     1 
ATOM   4622  O  O     . VAL B 1 72  ? 10.320  -4.836  -37.349  1.00 62.41  ? 72  VAL B O     1 
ATOM   4623  C  CB    . VAL B 1 72  ? 12.141  -2.986  -39.412  1.00 62.94  ? 72  VAL B CB    1 
ATOM   4624  C  CG1   . VAL B 1 72  ? 12.700  -2.841  -38.006  1.00 59.62  ? 72  VAL B CG1   1 
ATOM   4625  C  CG2   . VAL B 1 72  ? 13.251  -3.226  -40.433  1.00 65.68  ? 72  VAL B CG2   1 
ATOM   4626  N  N     . ALA B 1 73  ? 9.142   -3.161  -38.330  1.00 64.13  ? 73  ALA B N     1 
ATOM   4627  C  CA    . ALA B 1 73  ? 8.137   -3.113  -37.281  1.00 57.70  ? 73  ALA B CA    1 
ATOM   4628  C  C     . ALA B 1 73  ? 7.499   -4.495  -37.124  1.00 55.48  ? 73  ALA B C     1 
ATOM   4629  O  O     . ALA B 1 73  ? 7.256   -4.945  -36.007  1.00 53.34  ? 73  ALA B O     1 
ATOM   4630  C  CB    . ALA B 1 73  ? 7.115   -2.050  -37.589  1.00 61.97  ? 73  ALA B CB    1 
ATOM   4631  N  N     . ASN B 1 74  ? 7.223   -5.167  -38.248  1.00 58.79  ? 74  ASN B N     1 
ATOM   4632  C  CA    . ASN B 1 74  ? 6.765   -6.546  -38.200  1.00 59.48  ? 74  ASN B CA    1 
ATOM   4633  C  C     . ASN B 1 74  ? 7.818   -7.384  -37.469  1.00 65.83  ? 74  ASN B C     1 
ATOM   4634  O  O     . ASN B 1 74  ? 7.582   -7.851  -36.357  1.00 57.06  ? 74  ASN B O     1 
ATOM   4635  C  CB    . ASN B 1 74  ? 6.412   -7.090  -39.589  1.00 57.20  ? 74  ASN B CB    1 
ATOM   4636  C  CG    . ASN B 1 74  ? 4.963   -6.835  -39.965  1.00 61.49  ? 74  ASN B CG    1 
ATOM   4637  O  OD1   . ASN B 1 74  ? 4.058   -7.310  -39.292  1.00 56.54  ? 74  ASN B OD1   1 
ATOM   4638  N  ND2   . ASN B 1 74  ? 4.722   -6.060  -41.008  1.00 57.59  ? 74  ASN B ND2   1 
ATOM   4639  N  N     . GLU B 1 75  ? 9.002   -7.533  -38.073  1.00 73.28  ? 75  GLU B N     1 
ATOM   4640  C  CA    . GLU B 1 75  ? 10.037  -8.393  -37.520  1.00 71.14  ? 75  GLU B CA    1 
ATOM   4641  C  C     . GLU B 1 75  ? 10.091  -8.305  -35.998  1.00 65.37  ? 75  GLU B C     1 
ATOM   4642  O  O     . GLU B 1 75  ? 10.149  -9.339  -35.340  1.00 61.69  ? 75  GLU B O     1 
ATOM   4643  C  CB    . GLU B 1 75  ? 11.410  -8.064  -38.102  1.00 76.79  ? 75  GLU B CB    1 
ATOM   4644  C  CG    . GLU B 1 75  ? 11.753  -8.896  -39.325  1.00 79.95  ? 75  GLU B CG    1 
ATOM   4645  C  CD    . GLU B 1 75  ? 13.246  -9.078  -39.530  1.00 87.39  ? 75  GLU B CD    1 
ATOM   4646  O  OE1   . GLU B 1 75  ? 13.626  -9.924  -40.367  1.00 88.55  ? 75  GLU B OE1   1 
ATOM   4647  O  OE2   . GLU B 1 75  ? 14.024  -8.379  -38.840  1.00 78.81  ? 75  GLU B OE2   1 
ATOM   4648  N  N     . PHE B 1 76  ? 10.056  -7.086  -35.447  1.00 59.96  ? 76  PHE B N     1 
ATOM   4649  C  CA    . PHE B 1 76  ? 10.361  -6.876  -34.047  1.00 59.90  ? 76  PHE B CA    1 
ATOM   4650  C  C     . PHE B 1 76  ? 9.120   -6.672  -33.185  1.00 66.31  ? 76  PHE B C     1 
ATOM   4651  O  O     . PHE B 1 76  ? 9.269   -6.486  -31.978  1.00 60.01  ? 76  PHE B O     1 
ATOM   4652  C  CB    . PHE B 1 76  ? 11.306  -5.685  -33.923  1.00 72.39  ? 76  PHE B CB    1 
ATOM   4653  C  CG    . PHE B 1 76  ? 12.727  -6.053  -34.244  1.00 83.22  ? 76  PHE B CG    1 
ATOM   4654  C  CD1   . PHE B 1 76  ? 13.555  -6.570  -33.259  1.00 89.01  ? 76  PHE B CD1   1 
ATOM   4655  C  CD2   . PHE B 1 76  ? 13.205  -5.973  -35.542  1.00 88.84  ? 76  PHE B CD2   1 
ATOM   4656  C  CE1   . PHE B 1 76  ? 14.858  -6.937  -33.557  1.00 92.48  ? 76  PHE B CE1   1 
ATOM   4657  C  CE2   . PHE B 1 76  ? 14.508  -6.347  -35.836  1.00 93.29  ? 76  PHE B CE2   1 
ATOM   4658  C  CZ    . PHE B 1 76  ? 15.332  -6.823  -34.843  1.00 90.46  ? 76  PHE B CZ    1 
ATOM   4659  N  N     . GLY B 1 77  ? 7.914   -6.723  -33.780  1.00 61.87  ? 77  GLY B N     1 
ATOM   4660  C  CA    . GLY B 1 77  ? 6.681   -6.566  -33.017  1.00 54.79  ? 77  GLY B CA    1 
ATOM   4661  C  C     . GLY B 1 77  ? 6.521   -5.159  -32.443  1.00 54.06  ? 77  GLY B C     1 
ATOM   4662  O  O     . GLY B 1 77  ? 5.887   -4.972  -31.416  1.00 59.53  ? 77  GLY B O     1 
ATOM   4663  N  N     . VAL B 1 78  ? 7.070   -4.157  -33.129  1.00 57.15  ? 78  VAL B N     1 
ATOM   4664  C  CA    . VAL B 1 78  ? 7.056   -2.788  -32.636  1.00 59.12  ? 78  VAL B CA    1 
ATOM   4665  C  C     . VAL B 1 78  ? 5.908   -2.040  -33.296  1.00 57.99  ? 78  VAL B C     1 
ATOM   4666  O  O     . VAL B 1 78  ? 5.830   -2.012  -34.519  1.00 64.92  ? 78  VAL B O     1 
ATOM   4667  C  CB    . VAL B 1 78  ? 8.383   -2.079  -32.952  1.00 62.18  ? 78  VAL B CB    1 
ATOM   4668  C  CG1   . VAL B 1 78  ? 8.452   -0.694  -32.325  1.00 59.82  ? 78  VAL B CG1   1 
ATOM   4669  C  CG2   . VAL B 1 78  ? 9.567   -2.932  -32.530  1.00 70.12  ? 78  VAL B CG2   1 
ATOM   4670  N  N     . PRO B 1 79  ? 4.999   -1.401  -32.529  1.00 58.51  ? 79  PRO B N     1 
ATOM   4671  C  CA    . PRO B 1 79  ? 3.864   -0.697  -33.119  1.00 53.63  ? 79  PRO B CA    1 
ATOM   4672  C  C     . PRO B 1 79  ? 4.190   0.736   -33.540  1.00 56.71  ? 79  PRO B C     1 
ATOM   4673  O  O     . PRO B 1 79  ? 4.952   1.440   -32.867  1.00 50.17  ? 79  PRO B O     1 
ATOM   4674  C  CB    . PRO B 1 79  ? 2.811   -0.744  -32.001  1.00 56.82  ? 79  PRO B CB    1 
ATOM   4675  C  CG    . PRO B 1 79  ? 3.619   -0.795  -30.701  1.00 63.12  ? 79  PRO B CG    1 
ATOM   4676  C  CD    . PRO B 1 79  ? 4.983   -1.352  -31.060  1.00 60.94  ? 79  PRO B CD    1 
ATOM   4677  N  N     . LEU B 1 80  ? 3.555   1.147   -34.655  1.00 57.14  ? 80  LEU B N     1 
ATOM   4678  C  CA    . LEU B 1 80  ? 3.771   2.433   -35.301  1.00 51.64  ? 80  LEU B CA    1 
ATOM   4679  C  C     . LEU B 1 80  ? 2.486   3.247   -35.254  1.00 49.79  ? 80  LEU B C     1 
ATOM   4680  O  O     . LEU B 1 80  ? 1.391   2.719   -35.407  1.00 50.07  ? 80  LEU B O     1 
ATOM   4681  C  CB    . LEU B 1 80  ? 4.178   2.237   -36.764  1.00 50.75  ? 80  LEU B CB    1 
ATOM   4682  C  CG    . LEU B 1 80  ? 5.390   1.347   -37.037  1.00 51.59  ? 80  LEU B CG    1 
ATOM   4683  C  CD1   . LEU B 1 80  ? 5.586   1.159   -38.537  1.00 50.38  ? 80  LEU B CD1   1 
ATOM   4684  C  CD2   . LEU B 1 80  ? 6.652   1.925   -36.393  1.00 51.44  ? 80  LEU B CD2   1 
ATOM   4685  N  N     . TRP B 1 81  ? 2.648   4.551   -35.066  1.00 45.29  ? 81  TRP B N     1 
ATOM   4686  C  CA    . TRP B 1 81  ? 1.556   5.488   -35.201  1.00 46.89  ? 81  TRP B CA    1 
ATOM   4687  C  C     . TRP B 1 81  ? 1.826   6.410   -36.391  1.00 53.16  ? 81  TRP B C     1 
ATOM   4688  O  O     . TRP B 1 81  ? 2.676   7.296   -36.288  1.00 51.28  ? 81  TRP B O     1 
ATOM   4689  C  CB    . TRP B 1 81  ? 1.413   6.292   -33.919  1.00 41.81  ? 81  TRP B CB    1 
ATOM   4690  C  CG    . TRP B 1 81  ? 0.142   7.073   -33.917  1.00 46.05  ? 81  TRP B CG    1 
ATOM   4691  C  CD1   . TRP B 1 81  ? -0.028  8.366   -34.305  1.00 47.51  ? 81  TRP B CD1   1 
ATOM   4692  C  CD2   . TRP B 1 81  ? -1.150  6.592   -33.516  1.00 47.55  ? 81  TRP B CD2   1 
ATOM   4693  N  NE1   . TRP B 1 81  ? -1.343  8.726   -34.170  1.00 54.35  ? 81  TRP B NE1   1 
ATOM   4694  C  CE2   . TRP B 1 81  ? -2.051  7.661   -33.677  1.00 46.86  ? 81  TRP B CE2   1 
ATOM   4695  C  CE3   . TRP B 1 81  ? -1.622  5.371   -33.011  1.00 51.85  ? 81  TRP B CE3   1 
ATOM   4696  C  CZ2   . TRP B 1 81  ? -3.405  7.541   -33.376  1.00 49.38  ? 81  TRP B CZ2   1 
ATOM   4697  C  CZ3   . TRP B 1 81  ? -2.957  5.258   -32.690  1.00 42.31  ? 81  TRP B CZ3   1 
ATOM   4698  C  CH2   . TRP B 1 81  ? -3.835  6.327   -32.885  1.00 48.03  ? 81  TRP B CH2   1 
ATOM   4699  N  N     . PRO B 1 82  ? 1.179   6.209   -37.566  1.00 44.25  ? 82  PRO B N     1 
ATOM   4700  C  CA    . PRO B 1 82  ? 1.435   7.060   -38.733  1.00 39.71  ? 82  PRO B CA    1 
ATOM   4701  C  C     . PRO B 1 82  ? 0.706   8.391   -38.664  1.00 43.07  ? 82  PRO B C     1 
ATOM   4702  O  O     . PRO B 1 82  ? -0.483  8.440   -38.343  1.00 49.70  ? 82  PRO B O     1 
ATOM   4703  C  CB    . PRO B 1 82  ? 0.934   6.232   -39.910  1.00 44.14  ? 82  PRO B CB    1 
ATOM   4704  C  CG    . PRO B 1 82  ? 0.750   4.826   -39.322  1.00 45.62  ? 82  PRO B CG    1 
ATOM   4705  C  CD    . PRO B 1 82  ? 0.328   5.062   -37.894  1.00 43.66  ? 82  PRO B CD    1 
ATOM   4706  N  N     . VAL B 1 83  ? 1.457   9.460   -38.929  1.00 40.91  ? 83  VAL B N     1 
ATOM   4707  C  CA    . VAL B 1 83  ? 0.911   10.805  -39.061  1.00 50.78  ? 83  VAL B CA    1 
ATOM   4708  C  C     . VAL B 1 83  ? 1.453   11.402  -40.355  1.00 51.94  ? 83  VAL B C     1 
ATOM   4709  O  O     . VAL B 1 83  ? 2.592   11.123  -40.738  1.00 51.63  ? 83  VAL B O     1 
ATOM   4710  C  CB    . VAL B 1 83  ? 1.269   11.704  -37.855  1.00 53.34  ? 83  VAL B CB    1 
ATOM   4711  C  CG1   . VAL B 1 83  ? 0.940   11.036  -36.533  1.00 56.47  ? 83  VAL B CG1   1 
ATOM   4712  C  CG2   . VAL B 1 83  ? 2.729   12.135  -37.866  1.00 55.84  ? 83  VAL B CG2   1 
ATOM   4713  N  N     . SER B 1 84  ? 0.625   12.215  -41.015  1.00 51.51  ? 84  SER B N     1 
ATOM   4714  C  CA    . SER B 1 84  ? 1.005   12.876  -42.250  1.00 48.00  ? 84  SER B CA    1 
ATOM   4715  C  C     . SER B 1 84  ? 1.896   14.071  -41.905  1.00 49.40  ? 84  SER B C     1 
ATOM   4716  O  O     . SER B 1 84  ? 3.010   14.202  -42.412  1.00 48.60  ? 84  SER B O     1 
ATOM   4717  C  CB    . SER B 1 84  ? -0.219  13.277  -43.071  1.00 50.32  ? 84  SER B CB    1 
ATOM   4718  O  OG    . SER B 1 84  ? -0.956  12.142  -43.524  1.00 44.69  ? 84  SER B OG    1 
ATOM   4719  N  N     . ARG B 1 85  ? 1.378   14.942  -41.044  1.00 48.10  ? 85  ARG B N     1 
ATOM   4720  C  CA    . ARG B 1 85  ? 2.115   16.068  -40.488  1.00 53.83  ? 85  ARG B CA    1 
ATOM   4721  C  C     . ARG B 1 85  ? 1.867   16.184  -38.988  1.00 54.49  ? 85  ARG B C     1 
ATOM   4722  O  O     . ARG B 1 85  ? 2.573   16.927  -38.317  1.00 58.64  ? 85  ARG B O     1 
ATOM   4723  C  CB    . ARG B 1 85  ? 1.714   17.370  -41.182  1.00 55.12  ? 85  ARG B CB    1 
ATOM   4724  C  CG    . ARG B 1 85  ? 2.345   17.520  -42.555  1.00 54.53  ? 85  ARG B CG    1 
ATOM   4725  C  CD    . ARG B 1 85  ? 1.773   18.674  -43.344  1.00 55.05  ? 85  ARG B CD    1 
ATOM   4726  N  NE    . ARG B 1 85  ? 1.818   19.908  -42.608  1.00 55.04  ? 85  ARG B NE    1 
ATOM   4727  C  CZ    . ARG B 1 85  ? 2.906   20.622  -42.358  1.00 60.28  ? 85  ARG B CZ    1 
ATOM   4728  N  NH1   . ARG B 1 85  ? 4.069   20.256  -42.862  1.00 51.63  ? 85  ARG B NH1   1 
ATOM   4729  N  NH2   . ARG B 1 85  ? 2.800   21.732  -41.639  1.00 64.55  ? 85  ARG B NH2   1 
ATOM   4730  N  N     . GLY B 1 86  ? 0.877   15.438  -38.469  1.00 55.77  ? 86  GLY B N     1 
ATOM   4731  C  CA    . GLY B 1 86  ? 0.640   15.350  -37.035  1.00 56.38  ? 86  GLY B CA    1 
ATOM   4732  C  C     . GLY B 1 86  ? 0.120   16.646  -36.399  1.00 56.65  ? 86  GLY B C     1 
ATOM   4733  O  O     . GLY B 1 86  ? 0.373   16.873  -35.219  1.00 61.92  ? 86  GLY B O     1 
ATOM   4734  N  N     . LYS B 1 87  ? -0.653  17.466  -37.140  1.00 56.11  ? 87  LYS B N     1 
ATOM   4735  C  CA    . LYS B 1 87  ? -1.160  18.730  -36.607  1.00 52.40  ? 87  LYS B CA    1 
ATOM   4736  C  C     . LYS B 1 87  ? -2.620  18.581  -36.173  1.00 57.47  ? 87  LYS B C     1 
ATOM   4737  O  O     . LYS B 1 87  ? -3.421  19.512  -36.320  1.00 56.89  ? 87  LYS B O     1 
ATOM   4738  C  CB    . LYS B 1 87  ? -0.994  19.847  -37.640  1.00 53.44  ? 87  LYS B CB    1 
ATOM   4739  C  CG    . LYS B 1 87  ? 0.400   19.961  -38.242  1.00 54.59  ? 87  LYS B CG    1 
ATOM   4740  C  CD    . LYS B 1 87  ? 1.516   20.072  -37.216  1.00 57.28  ? 87  LYS B CD    1 
ATOM   4741  C  CE    . LYS B 1 87  ? 2.865   20.347  -37.851  1.00 59.23  ? 87  LYS B CE    1 
ATOM   4742  N  NZ    . LYS B 1 87  ? 3.961   20.203  -36.870  1.00 58.45  ? 87  LYS B NZ    1 
ATOM   4743  N  N     . ASN B 1 88  ? -2.941  17.412  -35.598  1.00 50.21  ? 88  ASN B N     1 
ATOM   4744  C  CA    . ASN B 1 88  ? -4.306  17.049  -35.266  1.00 55.80  ? 88  ASN B CA    1 
ATOM   4745  C  C     . ASN B 1 88  ? -4.660  17.655  -33.904  1.00 55.32  ? 88  ASN B C     1 
ATOM   4746  O  O     . ASN B 1 88  ? -5.091  16.960  -32.982  1.00 57.86  ? 88  ASN B O     1 
ATOM   4747  C  CB    . ASN B 1 88  ? -4.518  15.526  -35.324  1.00 52.40  ? 88  ASN B CB    1 
ATOM   4748  C  CG    . ASN B 1 88  ? -5.927  15.143  -35.749  1.00 53.61  ? 88  ASN B CG    1 
ATOM   4749  O  OD1   . ASN B 1 88  ? -6.686  15.974  -36.242  1.00 50.02  ? 88  ASN B OD1   1 
ATOM   4750  N  ND2   . ASN B 1 88  ? -6.287  13.879  -35.590  1.00 51.10  ? 88  ASN B ND2   1 
ATOM   4751  N  N     . PHE B 1 89  ? -4.515  18.979  -33.822  1.00 54.28  ? 89  PHE B N     1 
ATOM   4752  C  CA    . PHE B 1 89  ? -4.861  19.744  -32.638  1.00 56.42  ? 89  PHE B CA    1 
ATOM   4753  C  C     . PHE B 1 89  ? -6.344  19.549  -32.306  1.00 52.12  ? 89  PHE B C     1 
ATOM   4754  O  O     . PHE B 1 89  ? -7.190  19.719  -33.187  1.00 45.45  ? 89  PHE B O     1 
ATOM   4755  C  CB    . PHE B 1 89  ? -4.494  21.216  -32.867  1.00 56.70  ? 89  PHE B CB    1 
ATOM   4756  C  CG    . PHE B 1 89  ? -3.031  21.448  -33.156  1.00 68.61  ? 89  PHE B CG    1 
ATOM   4757  C  CD1   . PHE B 1 89  ? -2.084  21.390  -32.145  1.00 74.31  ? 89  PHE B CD1   1 
ATOM   4758  C  CD2   . PHE B 1 89  ? -2.592  21.675  -34.453  1.00 70.46  ? 89  PHE B CD2   1 
ATOM   4759  C  CE1   . PHE B 1 89  ? -0.735  21.576  -32.420  1.00 83.04  ? 89  PHE B CE1   1 
ATOM   4760  C  CE2   . PHE B 1 89  ? -1.244  21.853  -34.725  1.00 75.37  ? 89  PHE B CE2   1 
ATOM   4761  C  CZ    . PHE B 1 89  ? -0.317  21.804  -33.709  1.00 75.14  ? 89  PHE B CZ    1 
ATOM   4762  N  N     . ALA B 1 90  ? -6.616  19.239  -31.017  1.00 49.10  ? 90  ALA B N     1 
ATOM   4763  C  CA    . ALA B 1 90  ? -7.943  19.040  -30.426  1.00 52.73  ? 90  ALA B CA    1 
ATOM   4764  C  C     . ALA B 1 90  ? -8.290  17.547  -30.382  1.00 48.87  ? 90  ALA B C     1 
ATOM   4765  O  O     . ALA B 1 90  ? -9.256  17.137  -29.719  1.00 48.65  ? 90  ALA B O     1 
ATOM   4766  C  CB    . ALA B 1 90  ? -9.012  19.847  -31.140  1.00 56.02  ? 90  ALA B CB    1 
ATOM   4767  N  N     . TYR B 1 91  ? -7.454  16.756  -31.077  1.00 45.78  ? 91  TYR B N     1 
ATOM   4768  C  CA    . TYR B 1 91  ? -7.684  15.339  -31.263  1.00 54.01  ? 91  TYR B CA    1 
ATOM   4769  C  C     . TYR B 1 91  ? -6.464  14.539  -30.822  1.00 47.51  ? 91  TYR B C     1 
ATOM   4770  O  O     . TYR B 1 91  ? -6.442  13.334  -31.032  1.00 50.06  ? 91  TYR B O     1 
ATOM   4771  C  CB    . TYR B 1 91  ? -8.059  15.035  -32.720  1.00 55.21  ? 91  TYR B CB    1 
ATOM   4772  C  CG    . TYR B 1 91  ? -9.363  15.634  -33.191  1.00 57.31  ? 91  TYR B CG    1 
ATOM   4773  C  CD1   . TYR B 1 91  ? -10.571 15.347  -32.559  1.00 61.14  ? 91  TYR B CD1   1 
ATOM   4774  C  CD2   . TYR B 1 91  ? -9.387  16.505  -34.266  1.00 53.12  ? 91  TYR B CD2   1 
ATOM   4775  C  CE1   . TYR B 1 91  ? -11.766 15.910  -32.984  1.00 53.93  ? 91  TYR B CE1   1 
ATOM   4776  C  CE2   . TYR B 1 91  ? -10.569 17.066  -34.708  1.00 50.00  ? 91  TYR B CE2   1 
ATOM   4777  C  CZ    . TYR B 1 91  ? -11.759 16.754  -34.081  1.00 54.15  ? 91  TYR B CZ    1 
ATOM   4778  O  OH    . TYR B 1 91  ? -12.874 17.348  -34.585  1.00 52.26  ? 91  TYR B OH    1 
ATOM   4779  N  N     . GLY B 1 92  ? -5.492  15.198  -30.174  1.00 52.12  ? 92  GLY B N     1 
ATOM   4780  C  CA    . GLY B 1 92  ? -4.288  14.533  -29.686  1.00 50.54  ? 92  GLY B CA    1 
ATOM   4781  C  C     . GLY B 1 92  ? -2.977  15.018  -30.316  1.00 53.36  ? 92  GLY B C     1 
ATOM   4782  O  O     . GLY B 1 92  ? -1.889  14.627  -29.869  1.00 55.01  ? 92  GLY B O     1 
ATOM   4783  N  N     . GLY B 1 93  ? -3.076  15.859  -31.354  1.00 50.04  ? 93  GLY B N     1 
ATOM   4784  C  CA    . GLY B 1 93  ? -1.919  16.194  -32.163  1.00 55.48  ? 93  GLY B CA    1 
ATOM   4785  C  C     . GLY B 1 93  ? -1.353  14.933  -32.818  1.00 55.85  ? 93  GLY B C     1 
ATOM   4786  O  O     . GLY B 1 93  ? -2.094  14.156  -33.406  1.00 57.49  ? 93  GLY B O     1 
ATOM   4787  N  N     . ALA B 1 94  ? -0.052  14.698  -32.632  1.00 53.33  ? 94  ALA B N     1 
ATOM   4788  C  CA    . ALA B 1 94  ? 0.621   13.543  -33.198  1.00 54.03  ? 94  ALA B CA    1 
ATOM   4789  C  C     . ALA B 1 94  ? 0.679   12.361  -32.222  1.00 54.28  ? 94  ALA B C     1 
ATOM   4790  O  O     . ALA B 1 94  ? 1.268   11.336  -32.546  1.00 57.98  ? 94  ALA B O     1 
ATOM   4791  C  CB    . ALA B 1 94  ? 2.007   13.959  -33.636  1.00 54.48  ? 94  ALA B CB    1 
ATOM   4792  N  N     . ALA B 1 95  ? 0.040   12.450  -31.047  1.00 57.61  ? 95  ALA B N     1 
ATOM   4793  C  CA    . ALA B 1 95  ? 0.274   11.450  -30.007  1.00 59.03  ? 95  ALA B CA    1 
ATOM   4794  C  C     . ALA B 1 95  ? -0.478  10.158  -30.326  1.00 58.00  ? 95  ALA B C     1 
ATOM   4795  O  O     . ALA B 1 95  ? -1.527  10.194  -30.970  1.00 56.53  ? 95  ALA B O     1 
ATOM   4796  C  CB    . ALA B 1 95  ? -0.115  11.998  -28.645  1.00 54.54  ? 95  ALA B CB    1 
ATOM   4797  N  N     . PRO B 1 96  ? 0.015   8.979   -29.879  1.00 56.64  ? 96  PRO B N     1 
ATOM   4798  C  CA    . PRO B 1 96  ? -0.749  7.732   -29.999  1.00 58.33  ? 96  PRO B CA    1 
ATOM   4799  C  C     . PRO B 1 96  ? -1.817  7.521   -28.920  1.00 62.93  ? 96  PRO B C     1 
ATOM   4800  O  O     . PRO B 1 96  ? -1.785  8.136   -27.848  1.00 64.21  ? 96  PRO B O     1 
ATOM   4801  C  CB    . PRO B 1 96  ? 0.349   6.675   -29.866  1.00 59.67  ? 96  PRO B CB    1 
ATOM   4802  C  CG    . PRO B 1 96  ? 1.303   7.303   -28.870  1.00 63.95  ? 96  PRO B CG    1 
ATOM   4803  C  CD    . PRO B 1 96  ? 1.329   8.772   -29.251  1.00 59.39  ? 96  PRO B CD    1 
ATOM   4804  N  N     . VAL B 1 97  ? -2.794  6.663   -29.239  1.00 54.72  ? 97  VAL B N     1 
ATOM   4805  C  CA    . VAL B 1 97  ? -3.690  6.095   -28.245  1.00 58.90  ? 97  VAL B CA    1 
ATOM   4806  C  C     . VAL B 1 97  ? -2.862  5.397   -27.165  1.00 56.69  ? 97  VAL B C     1 
ATOM   4807  O  O     . VAL B 1 97  ? -2.932  5.733   -25.982  1.00 58.57  ? 97  VAL B O     1 
ATOM   4808  C  CB    . VAL B 1 97  ? -4.673  5.122   -28.921  1.00 60.37  ? 97  VAL B CB    1 
ATOM   4809  C  CG1   . VAL B 1 97  ? -5.333  4.161   -27.942  1.00 60.40  ? 97  VAL B CG1   1 
ATOM   4810  C  CG2   . VAL B 1 97  ? -5.709  5.880   -29.746  1.00 60.23  ? 97  VAL B CG2   1 
ATOM   4811  N  N     . MET B 1 98  ? -2.066  4.427   -27.602  1.00 54.24  ? 98  MET B N     1 
ATOM   4812  C  CA    . MET B 1 98  ? -1.369  3.545   -26.690  1.00 62.71  ? 98  MET B CA    1 
ATOM   4813  C  C     . MET B 1 98  ? 0.069   4.040   -26.497  1.00 65.70  ? 98  MET B C     1 
ATOM   4814  O  O     . MET B 1 98  ? 0.756   4.370   -27.468  1.00 62.62  ? 98  MET B O     1 
ATOM   4815  C  CB    . MET B 1 98  ? -1.382  2.115   -27.240  1.00 56.62  ? 98  MET B CB    1 
ATOM   4816  C  CG    . MET B 1 98  ? -0.948  1.068   -26.210  1.00 53.01  ? 98  MET B CG    1 
ATOM   4817  S  SD    . MET B 1 98  ? -0.597  -0.531  -26.973  1.00 58.16  ? 98  MET B SD    1 
ATOM   4818  C  CE    . MET B 1 98  ? 0.940   -0.177  -27.826  1.00 53.57  ? 98  MET B CE    1 
ATOM   4819  N  N     . SER B 1 99  ? 0.507   4.105   -25.227  1.00 62.06  ? 99  SER B N     1 
ATOM   4820  C  CA    . SER B 1 99  ? 1.859   4.550   -24.899  1.00 62.42  ? 99  SER B CA    1 
ATOM   4821  C  C     . SER B 1 99  ? 2.901   3.549   -25.400  1.00 58.46  ? 99  SER B C     1 
ATOM   4822  O  O     . SER B 1 99  ? 2.679   2.337   -25.362  1.00 63.97  ? 99  SER B O     1 
ATOM   4823  C  CB    . SER B 1 99  ? 2.020   4.785   -23.416  1.00 63.08  ? 99  SER B CB    1 
ATOM   4824  O  OG    . SER B 1 99  ? 1.293   5.932   -22.988  1.00 60.08  ? 99  SER B OG    1 
ATOM   4825  N  N     . GLY B 1 100 ? 4.054   4.073   -25.839  1.00 58.49  ? 100 GLY B N     1 
ATOM   4826  C  CA    . GLY B 1 100 ? 5.160   3.259   -26.319  1.00 54.48  ? 100 GLY B CA    1 
ATOM   4827  C  C     . GLY B 1 100 ? 5.128   3.085   -27.837  1.00 63.79  ? 100 GLY B C     1 
ATOM   4828  O  O     . GLY B 1 100 ? 6.015   2.465   -28.418  1.00 60.35  ? 100 GLY B O     1 
ATOM   4829  N  N     . THR B 1 101 ? 4.090   3.618   -28.483  1.00 65.13  ? 101 THR B N     1 
ATOM   4830  C  CA    . THR B 1 101 ? 3.968   3.475   -29.923  1.00 64.94  ? 101 THR B CA    1 
ATOM   4831  C  C     . THR B 1 101 ? 4.932   4.447   -30.583  1.00 68.64  ? 101 THR B C     1 
ATOM   4832  O  O     . THR B 1 101 ? 4.971   5.620   -30.217  1.00 72.15  ? 101 THR B O     1 
ATOM   4833  C  CB    . THR B 1 101 ? 2.537   3.746   -30.404  1.00 66.04  ? 101 THR B CB    1 
ATOM   4834  O  OG1   . THR B 1 101 ? 1.593   2.956   -29.680  1.00 63.99  ? 101 THR B OG1   1 
ATOM   4835  C  CG2   . THR B 1 101 ? 2.363   3.461   -31.877  1.00 72.51  ? 101 THR B CG2   1 
ATOM   4836  N  N     . VAL B 1 102 ? 5.687   3.940   -31.560  1.00 68.18  ? 102 VAL B N     1 
ATOM   4837  C  CA    . VAL B 1 102 ? 6.655   4.742   -32.281  1.00 69.23  ? 102 VAL B CA    1 
ATOM   4838  C  C     . VAL B 1 102 ? 5.979   5.493   -33.425  1.00 65.68  ? 102 VAL B C     1 
ATOM   4839  O  O     . VAL B 1 102 ? 5.573   4.882   -34.404  1.00 68.81  ? 102 VAL B O     1 
ATOM   4840  C  CB    . VAL B 1 102 ? 7.780   3.855   -32.825  1.00 71.65  ? 102 VAL B CB    1 
ATOM   4841  C  CG1   . VAL B 1 102 ? 8.697   4.647   -33.743  1.00 74.10  ? 102 VAL B CG1   1 
ATOM   4842  C  CG2   . VAL B 1 102 ? 8.549   3.203   -31.690  1.00 75.81  ? 102 VAL B CG2   1 
ATOM   4843  N  N     . VAL B 1 103 ? 5.950   6.824   -33.329  1.00 57.93  ? 103 VAL B N     1 
ATOM   4844  C  CA    . VAL B 1 103 ? 5.343   7.672   -34.342  1.00 57.55  ? 103 VAL B CA    1 
ATOM   4845  C  C     . VAL B 1 103 ? 6.075   7.506   -35.678  1.00 57.54  ? 103 VAL B C     1 
ATOM   4846  O  O     . VAL B 1 103 ? 7.298   7.546   -35.729  1.00 52.64  ? 103 VAL B O     1 
ATOM   4847  C  CB    . VAL B 1 103 ? 5.332   9.143   -33.886  1.00 57.95  ? 103 VAL B CB    1 
ATOM   4848  C  CG1   . VAL B 1 103 ? 4.794   10.071  -34.968  1.00 60.23  ? 103 VAL B CG1   1 
ATOM   4849  C  CG2   . VAL B 1 103 ? 4.545   9.317   -32.597  1.00 57.45  ? 103 VAL B CG2   1 
ATOM   4850  N  N     . LEU B 1 104 ? 5.311   7.262   -36.755  1.00 53.67  ? 104 LEU B N     1 
ATOM   4851  C  CA    . LEU B 1 104 ? 5.837   7.280   -38.111  1.00 51.09  ? 104 LEU B CA    1 
ATOM   4852  C  C     . LEU B 1 104 ? 5.375   8.578   -38.753  1.00 52.31  ? 104 LEU B C     1 
ATOM   4853  O  O     . LEU B 1 104 ? 4.217   8.713   -39.166  1.00 50.02  ? 104 LEU B O     1 
ATOM   4854  C  CB    . LEU B 1 104 ? 5.354   6.053   -38.887  1.00 53.52  ? 104 LEU B CB    1 
ATOM   4855  C  CG    . LEU B 1 104 ? 5.554   6.101   -40.401  1.00 52.86  ? 104 LEU B CG    1 
ATOM   4856  C  CD1   . LEU B 1 104 ? 7.020   6.174   -40.760  1.00 54.59  ? 104 LEU B CD1   1 
ATOM   4857  C  CD2   . LEU B 1 104 ? 4.925   4.887   -41.069  1.00 55.71  ? 104 LEU B CD2   1 
ATOM   4858  N  N     . ASP B 1 105 ? 6.286   9.551   -38.749  1.00 47.69  ? 105 ASP B N     1 
ATOM   4859  C  CA    . ASP B 1 105 ? 5.977   10.909  -39.157  1.00 50.79  ? 105 ASP B CA    1 
ATOM   4860  C  C     . ASP B 1 105 ? 6.467   11.089  -40.586  1.00 52.85  ? 105 ASP B C     1 
ATOM   4861  O  O     . ASP B 1 105 ? 7.672   10.949  -40.857  1.00 49.45  ? 105 ASP B O     1 
ATOM   4862  C  CB    . ASP B 1 105 ? 6.631   11.901  -38.197  1.00 54.97  ? 105 ASP B CB    1 
ATOM   4863  C  CG    . ASP B 1 105 ? 6.502   13.364  -38.566  1.00 56.48  ? 105 ASP B CG    1 
ATOM   4864  O  OD1   . ASP B 1 105 ? 5.872   13.681  -39.599  1.00 53.14  ? 105 ASP B OD1   1 
ATOM   4865  O  OD2   . ASP B 1 105 ? 7.039   14.178  -37.807  1.00 63.69  ? 105 ASP B OD2   1 
ATOM   4866  N  N     . MET B 1 106 ? 5.529   11.429  -41.484  1.00 44.47  ? 106 MET B N     1 
ATOM   4867  C  CA    . MET B 1 106 ? 5.857   11.497  -42.904  1.00 44.65  ? 106 MET B CA    1 
ATOM   4868  C  C     . MET B 1 106 ? 5.927   12.944  -43.399  1.00 41.92  ? 106 MET B C     1 
ATOM   4869  O  O     . MET B 1 106 ? 5.737   13.208  -44.583  1.00 44.22  ? 106 MET B O     1 
ATOM   4870  C  CB    . MET B 1 106 ? 4.830   10.687  -43.693  1.00 48.37  ? 106 MET B CB    1 
ATOM   4871  C  CG    . MET B 1 106 ? 5.070   9.208   -43.525  1.00 52.05  ? 106 MET B CG    1 
ATOM   4872  S  SD    . MET B 1 106 ? 3.798   8.219   -44.311  1.00 57.40  ? 106 MET B SD    1 
ATOM   4873  C  CE    . MET B 1 106 ? 2.356   8.664   -43.350  1.00 61.78  ? 106 MET B CE    1 
ATOM   4874  N  N     . ASN B 1 107 ? 6.204   13.876  -42.483  1.00 45.82  ? 107 ASN B N     1 
ATOM   4875  C  CA    . ASN B 1 107 ? 6.362   15.288  -42.802  1.00 48.96  ? 107 ASN B CA    1 
ATOM   4876  C  C     . ASN B 1 107 ? 7.292   15.508  -43.982  1.00 48.20  ? 107 ASN B C     1 
ATOM   4877  O  O     . ASN B 1 107 ? 7.060   16.405  -44.789  1.00 46.16  ? 107 ASN B O     1 
ATOM   4878  C  CB    . ASN B 1 107 ? 6.987   16.074  -41.649  1.00 58.64  ? 107 ASN B CB    1 
ATOM   4879  C  CG    . ASN B 1 107 ? 5.935   16.737  -40.800  1.00 73.78  ? 107 ASN B CG    1 
ATOM   4880  O  OD1   . ASN B 1 107 ? 5.640   16.285  -39.696  1.00 101.14 ? 107 ASN B OD1   1 
ATOM   4881  N  ND2   . ASN B 1 107 ? 5.343   17.794  -41.331  1.00 80.58  ? 107 ASN B ND2   1 
ATOM   4882  N  N     . ARG B 1 108 ? 8.384   14.744  -44.027  1.00 44.82  ? 108 ARG B N     1 
ATOM   4883  C  CA    . ARG B 1 108 ? 9.427   15.033  -45.001  1.00 48.88  ? 108 ARG B CA    1 
ATOM   4884  C  C     . ARG B 1 108 ? 8.967   14.611  -46.392  1.00 50.36  ? 108 ARG B C     1 
ATOM   4885  O  O     . ARG B 1 108 ? 9.464   15.127  -47.386  1.00 43.88  ? 108 ARG B O     1 
ATOM   4886  C  CB    . ARG B 1 108 ? 10.745  14.360  -44.599  1.00 52.46  ? 108 ARG B CB    1 
ATOM   4887  C  CG    . ARG B 1 108 ? 11.261  14.793  -43.233  1.00 56.41  ? 108 ARG B CG    1 
ATOM   4888  C  CD    . ARG B 1 108 ? 12.516  14.030  -42.836  1.00 60.94  ? 108 ARG B CD    1 
ATOM   4889  N  NE    . ARG B 1 108 ? 13.561  14.103  -43.850  1.00 56.94  ? 108 ARG B NE    1 
ATOM   4890  C  CZ    . ARG B 1 108 ? 14.212  13.060  -44.353  1.00 57.39  ? 108 ARG B CZ    1 
ATOM   4891  N  NH1   . ARG B 1 108 ? 14.056  11.854  -43.842  1.00 58.17  ? 108 ARG B NH1   1 
ATOM   4892  N  NH2   . ARG B 1 108 ? 15.044  13.229  -45.364  1.00 65.55  ? 108 ARG B NH2   1 
ATOM   4893  N  N     . MET B 1 109 ? 7.971   13.716  -46.438  1.00 51.46  ? 109 MET B N     1 
ATOM   4894  C  CA    . MET B 1 109 ? 7.309   13.306  -47.664  1.00 42.70  ? 109 MET B CA    1 
ATOM   4895  C  C     . MET B 1 109 ? 6.297   14.366  -48.098  1.00 45.00  ? 109 MET B C     1 
ATOM   4896  O  O     . MET B 1 109 ? 5.076   14.201  -47.976  1.00 47.13  ? 109 MET B O     1 
ATOM   4897  C  CB    . MET B 1 109 ? 6.651   11.939  -47.442  1.00 46.44  ? 109 MET B CB    1 
ATOM   4898  C  CG    . MET B 1 109 ? 7.699   10.830  -47.386  1.00 47.57  ? 109 MET B CG    1 
ATOM   4899  S  SD    . MET B 1 109 ? 7.092   9.218   -46.879  1.00 54.94  ? 109 MET B SD    1 
ATOM   4900  C  CE    . MET B 1 109 ? 6.455   8.593   -48.432  1.00 55.34  ? 109 MET B CE    1 
ATOM   4901  N  N     . ASN B 1 110 ? 6.831   15.447  -48.679  1.00 44.15  ? 110 ASN B N     1 
ATOM   4902  C  CA    . ASN B 1 110 ? 6.083   16.673  -48.889  1.00 42.62  ? 110 ASN B CA    1 
ATOM   4903  C  C     . ASN B 1 110 ? 6.103   17.074  -50.357  1.00 39.00  ? 110 ASN B C     1 
ATOM   4904  O  O     . ASN B 1 110 ? 6.004   18.257  -50.654  1.00 40.66  ? 110 ASN B O     1 
ATOM   4905  C  CB    . ASN B 1 110 ? 6.633   17.790  -48.009  1.00 47.08  ? 110 ASN B CB    1 
ATOM   4906  C  CG    . ASN B 1 110 ? 8.042   18.188  -48.381  1.00 47.52  ? 110 ASN B CG    1 
ATOM   4907  O  OD1   . ASN B 1 110 ? 8.739   17.463  -49.078  1.00 52.77  ? 110 ASN B OD1   1 
ATOM   4908  N  ND2   . ASN B 1 110 ? 8.464   19.352  -47.941  1.00 50.26  ? 110 ASN B ND2   1 
ATOM   4909  N  N     . ARG B 1 111 ? 6.192   16.095  -51.271  1.00 43.28  ? 111 ARG B N     1 
ATOM   4910  C  CA    . ARG B 1 111 ? 6.153   16.385  -52.703  1.00 50.83  ? 111 ARG B CA    1 
ATOM   4911  C  C     . ARG B 1 111 ? 4.719   16.614  -53.184  1.00 46.02  ? 111 ARG B C     1 
ATOM   4912  O  O     . ARG B 1 111 ? 3.861   15.738  -53.059  1.00 45.39  ? 111 ARG B O     1 
ATOM   4913  C  CB    . ARG B 1 111 ? 6.719   15.243  -53.551  1.00 50.09  ? 111 ARG B CB    1 
ATOM   4914  C  CG    . ARG B 1 111 ? 8.164   14.893  -53.252  1.00 61.02  ? 111 ARG B CG    1 
ATOM   4915  C  CD    . ARG B 1 111 ? 8.591   13.561  -53.844  1.00 71.95  ? 111 ARG B CD    1 
ATOM   4916  N  NE    . ARG B 1 111 ? 9.852   13.139  -53.237  1.00 83.80  ? 111 ARG B NE    1 
ATOM   4917  C  CZ    . ARG B 1 111 ? 10.160  11.896  -52.868  1.00 101.61 ? 111 ARG B CZ    1 
ATOM   4918  N  NH1   . ARG B 1 111 ? 9.335   10.894  -53.125  1.00 111.98 ? 111 ARG B NH1   1 
ATOM   4919  N  NH2   . ARG B 1 111 ? 11.295  11.665  -52.226  1.00 96.78  ? 111 ARG B NH2   1 
ATOM   4920  N  N     . ILE B 1 112 ? 4.505   17.784  -53.778  1.00 37.25  ? 112 ILE B N     1 
ATOM   4921  C  CA    . ILE B 1 112 ? 3.386   18.015  -54.658  1.00 41.49  ? 112 ILE B CA    1 
ATOM   4922  C  C     . ILE B 1 112 ? 3.676   17.315  -55.987  1.00 47.95  ? 112 ILE B C     1 
ATOM   4923  O  O     . ILE B 1 112 ? 4.370   17.865  -56.833  1.00 48.17  ? 112 ILE B O     1 
ATOM   4924  C  CB    . ILE B 1 112 ? 3.155   19.524  -54.819  1.00 41.96  ? 112 ILE B CB    1 
ATOM   4925  C  CG1   . ILE B 1 112 ? 2.925   20.202  -53.462  1.00 44.57  ? 112 ILE B CG1   1 
ATOM   4926  C  CG2   . ILE B 1 112 ? 2.015   19.772  -55.801  1.00 40.69  ? 112 ILE B CG2   1 
ATOM   4927  C  CD1   . ILE B 1 112 ? 2.801   21.723  -53.542  1.00 45.98  ? 112 ILE B CD1   1 
ATOM   4928  N  N     . LEU B 1 113 ? 3.145   16.096  -56.155  1.00 42.86  ? 113 LEU B N     1 
ATOM   4929  C  CA    . LEU B 1 113 ? 3.479   15.245  -57.289  1.00 42.91  ? 113 LEU B CA    1 
ATOM   4930  C  C     . LEU B 1 113 ? 2.887   15.754  -58.593  1.00 47.09  ? 113 LEU B C     1 
ATOM   4931  O  O     . LEU B 1 113 ? 3.488   15.547  -59.650  1.00 40.15  ? 113 LEU B O     1 
ATOM   4932  C  CB    . LEU B 1 113 ? 2.974   13.835  -57.005  1.00 44.93  ? 113 LEU B CB    1 
ATOM   4933  C  CG    . LEU B 1 113 ? 3.691   13.149  -55.846  1.00 48.55  ? 113 LEU B CG    1 
ATOM   4934  C  CD1   . LEU B 1 113 ? 3.077   11.800  -55.531  1.00 47.58  ? 113 LEU B CD1   1 
ATOM   4935  C  CD2   . LEU B 1 113 ? 5.177   13.005  -56.170  1.00 49.76  ? 113 LEU B CD2   1 
ATOM   4936  N  N     . GLU B 1 114 ? 1.688   16.349  -58.516  1.00 44.17  ? 114 GLU B N     1 
ATOM   4937  C  CA    . GLU B 1 114 ? 1.053   16.938  -59.681  1.00 46.75  ? 114 GLU B CA    1 
ATOM   4938  C  C     . GLU B 1 114 ? -0.063  17.889  -59.255  1.00 43.43  ? 114 GLU B C     1 
ATOM   4939  O  O     . GLU B 1 114 ? -0.793  17.605  -58.318  1.00 44.13  ? 114 GLU B O     1 
ATOM   4940  C  CB    . GLU B 1 114 ? 0.484   15.857  -60.600  1.00 47.24  ? 114 GLU B CB    1 
ATOM   4941  C  CG    . GLU B 1 114 ? -0.029  16.441  -61.898  1.00 56.11  ? 114 GLU B CG    1 
ATOM   4942  C  CD    . GLU B 1 114 ? -0.725  15.482  -62.851  1.00 62.29  ? 114 GLU B CD    1 
ATOM   4943  O  OE1   . GLU B 1 114 ? -0.771  14.260  -62.567  1.00 54.82  ? 114 GLU B OE1   1 
ATOM   4944  O  OE2   . GLU B 1 114 ? -1.232  15.984  -63.886  1.00 62.19  ? 114 GLU B OE2   1 
ATOM   4945  N  N     . VAL B 1 115 ? -0.153  19.043  -59.922  1.00 41.89  ? 115 VAL B N     1 
ATOM   4946  C  CA    . VAL B 1 115 ? -1.350  19.850  -59.901  1.00 40.83  ? 115 VAL B CA    1 
ATOM   4947  C  C     . VAL B 1 115 ? -1.751  20.061  -61.354  1.00 48.35  ? 115 VAL B C     1 
ATOM   4948  O  O     . VAL B 1 115 ? -0.981  20.631  -62.131  1.00 43.29  ? 115 VAL B O     1 
ATOM   4949  C  CB    . VAL B 1 115 ? -1.189  21.188  -59.158  1.00 42.55  ? 115 VAL B CB    1 
ATOM   4950  C  CG1   . VAL B 1 115 ? -2.543  21.859  -58.962  1.00 41.15  ? 115 VAL B CG1   1 
ATOM   4951  C  CG2   . VAL B 1 115 ? -0.496  21.024  -57.820  1.00 43.25  ? 115 VAL B CG2   1 
ATOM   4952  N  N     . ASN B 1 116 ? -2.983  19.633  -61.661  1.00 42.40  ? 116 ASN B N     1 
ATOM   4953  C  CA    . ASN B 1 116 ? -3.556  19.659  -62.991  1.00 41.19  ? 116 ASN B CA    1 
ATOM   4954  C  C     . ASN B 1 116 ? -4.678  20.683  -63.048  1.00 44.24  ? 116 ASN B C     1 
ATOM   4955  O  O     . ASN B 1 116 ? -5.717  20.527  -62.400  1.00 44.68  ? 116 ASN B O     1 
ATOM   4956  C  CB    . ASN B 1 116 ? -4.107  18.282  -63.346  1.00 42.47  ? 116 ASN B CB    1 
ATOM   4957  C  CG    . ASN B 1 116 ? -4.565  18.197  -64.779  1.00 40.03  ? 116 ASN B CG    1 
ATOM   4958  O  OD1   . ASN B 1 116 ? -5.380  18.994  -65.248  1.00 43.61  ? 116 ASN B OD1   1 
ATOM   4959  N  ND2   . ASN B 1 116 ? -4.049  17.209  -65.471  1.00 41.57  ? 116 ASN B ND2   1 
ATOM   4960  N  N     . GLU B 1 117 ? -4.468  21.739  -63.830  1.00 45.89  ? 117 GLU B N     1 
ATOM   4961  C  CA    . GLU B 1 117 ? -5.399  22.846  -63.829  1.00 44.46  ? 117 GLU B CA    1 
ATOM   4962  C  C     . GLU B 1 117 ? -6.651  22.487  -64.629  1.00 49.18  ? 117 GLU B C     1 
ATOM   4963  O  O     . GLU B 1 117 ? -7.755  22.859  -64.244  1.00 43.50  ? 117 GLU B O     1 
ATOM   4964  C  CB    . GLU B 1 117 ? -4.721  24.095  -64.374  1.00 47.31  ? 117 GLU B CB    1 
ATOM   4965  C  CG    . GLU B 1 117 ? -5.595  25.340  -64.287  1.00 48.38  ? 117 GLU B CG    1 
ATOM   4966  C  CD    . GLU B 1 117 ? -4.959  26.558  -64.940  1.00 51.07  ? 117 GLU B CD    1 
ATOM   4967  O  OE1   . GLU B 1 117 ? -4.366  26.366  -66.016  1.00 57.16  ? 117 GLU B OE1   1 
ATOM   4968  O  OE2   . GLU B 1 117 ? -5.066  27.689  -64.385  1.00 45.79  ? 117 GLU B OE2   1 
ATOM   4969  N  N     . GLU B 1 118 ? -6.490  21.765  -65.743  1.00 43.82  ? 118 GLU B N     1 
ATOM   4970  C  CA    . GLU B 1 118 ? -7.616  21.552  -66.648  1.00 54.71  ? 118 GLU B CA    1 
ATOM   4971  C  C     . GLU B 1 118 ? -8.615  20.554  -66.042  1.00 50.23  ? 118 GLU B C     1 
ATOM   4972  O  O     . GLU B 1 118 ? -9.812  20.639  -66.321  1.00 41.78  ? 118 GLU B O     1 
ATOM   4973  C  CB    . GLU B 1 118 ? -7.186  21.041  -68.036  1.00 62.41  ? 118 GLU B CB    1 
ATOM   4974  C  CG    . GLU B 1 118 ? -5.894  21.629  -68.588  1.00 74.82  ? 118 GLU B CG    1 
ATOM   4975  C  CD    . GLU B 1 118 ? -4.634  20.875  -68.182  1.00 82.07  ? 118 GLU B CD    1 
ATOM   4976  O  OE1   . GLU B 1 118 ? -4.540  19.683  -68.542  1.00 96.29  ? 118 GLU B OE1   1 
ATOM   4977  O  OE2   . GLU B 1 118 ? -3.762  21.464  -67.479  1.00 65.11  ? 118 GLU B OE2   1 
ATOM   4978  N  N     . PHE B 1 119 ? -8.122  19.589  -65.248  1.00 40.11  ? 119 PHE B N     1 
ATOM   4979  C  CA    . PHE B 1 119 ? -8.998  18.614  -64.624  1.00 41.70  ? 119 PHE B CA    1 
ATOM   4980  C  C     . PHE B 1 119 ? -9.206  18.880  -63.134  1.00 43.35  ? 119 PHE B C     1 
ATOM   4981  O  O     . PHE B 1 119 ? -9.873  18.082  -62.486  1.00 44.92  ? 119 PHE B O     1 
ATOM   4982  C  CB    . PHE B 1 119 ? -8.465  17.201  -64.809  1.00 44.60  ? 119 PHE B CB    1 
ATOM   4983  C  CG    . PHE B 1 119 ? -8.696  16.655  -66.190  1.00 48.72  ? 119 PHE B CG    1 
ATOM   4984  C  CD1   . PHE B 1 119 ? -9.966  16.233  -66.572  1.00 53.13  ? 119 PHE B CD1   1 
ATOM   4985  C  CD2   . PHE B 1 119 ? -7.656  16.583  -67.104  1.00 48.08  ? 119 PHE B CD2   1 
ATOM   4986  C  CE1   . PHE B 1 119 ? -10.187 15.724  -67.842  1.00 52.67  ? 119 PHE B CE1   1 
ATOM   4987  C  CE2   . PHE B 1 119 ? -7.879  16.070  -68.369  1.00 52.72  ? 119 PHE B CE2   1 
ATOM   4988  C  CZ    . PHE B 1 119 ? -9.144  15.646  -68.735  1.00 54.85  ? 119 PHE B CZ    1 
ATOM   4989  N  N     . GLY B 1 120 ? -8.647  19.977  -62.602  1.00 41.51  ? 120 GLY B N     1 
ATOM   4990  C  CA    . GLY B 1 120 ? -8.937  20.411  -61.242  1.00 43.36  ? 120 GLY B CA    1 
ATOM   4991  C  C     . GLY B 1 120 ? -8.605  19.336  -60.205  1.00 39.05  ? 120 GLY B C     1 
ATOM   4992  O  O     . GLY B 1 120 ? -9.510  18.835  -59.539  1.00 48.19  ? 120 GLY B O     1 
ATOM   4993  N  N     . TYR B 1 121 ? -7.324  18.936  -60.142  1.00 35.55  ? 121 TYR B N     1 
ATOM   4994  C  CA    . TYR B 1 121 ? -6.866  18.015  -59.117  1.00 34.90  ? 121 TYR B CA    1 
ATOM   4995  C  C     . TYR B 1 121 ? -5.409  18.261  -58.721  1.00 37.96  ? 121 TYR B C     1 
ATOM   4996  O  O     . TYR B 1 121 ? -4.656  18.944  -59.414  1.00 40.43  ? 121 TYR B O     1 
ATOM   4997  C  CB    . TYR B 1 121 ? -7.081  16.545  -59.514  1.00 35.32  ? 121 TYR B CB    1 
ATOM   4998  C  CG    . TYR B 1 121 ? -6.166  15.957  -60.562  1.00 38.98  ? 121 TYR B CG    1 
ATOM   4999  C  CD1   . TYR B 1 121 ? -4.878  15.547  -60.248  1.00 42.34  ? 121 TYR B CD1   1 
ATOM   5000  C  CD2   . TYR B 1 121 ? -6.591  15.773  -61.865  1.00 37.32  ? 121 TYR B CD2   1 
ATOM   5001  C  CE1   . TYR B 1 121 ? -4.040  15.000  -61.198  1.00 36.79  ? 121 TYR B CE1   1 
ATOM   5002  C  CE2   . TYR B 1 121 ? -5.751  15.255  -62.834  1.00 40.33  ? 121 TYR B CE2   1 
ATOM   5003  C  CZ    . TYR B 1 121 ? -4.472  14.862  -62.501  1.00 39.44  ? 121 TYR B CZ    1 
ATOM   5004  O  OH    . TYR B 1 121 ? -3.615  14.319  -63.428  1.00 44.15  ? 121 TYR B OH    1 
ATOM   5005  N  N     . ALA B 1 122 ? -5.066  17.703  -57.557  1.00 34.13  ? 122 ALA B N     1 
ATOM   5006  C  CA    . ALA B 1 122 ? -3.690  17.533  -57.127  1.00 39.82  ? 122 ALA B CA    1 
ATOM   5007  C  C     . ALA B 1 122 ? -3.450  16.093  -56.663  1.00 38.91  ? 122 ALA B C     1 
ATOM   5008  O  O     . ALA B 1 122 ? -4.347  15.414  -56.148  1.00 42.39  ? 122 ALA B O     1 
ATOM   5009  C  CB    . ALA B 1 122 ? -3.382  18.512  -56.030  1.00 38.33  ? 122 ALA B CB    1 
ATOM   5010  N  N     . LEU B 1 123 ? -2.215  15.640  -56.855  1.00 41.08  ? 123 LEU B N     1 
ATOM   5011  C  CA    . LEU B 1 123 ? -1.714  14.391  -56.301  1.00 40.50  ? 123 LEU B CA    1 
ATOM   5012  C  C     . LEU B 1 123 ? -0.575  14.762  -55.366  1.00 47.44  ? 123 LEU B C     1 
ATOM   5013  O  O     . LEU B 1 123 ? 0.368   15.412  -55.813  1.00 45.31  ? 123 LEU B O     1 
ATOM   5014  C  CB    . LEU B 1 123 ? -1.208  13.522  -57.457  1.00 41.67  ? 123 LEU B CB    1 
ATOM   5015  C  CG    . LEU B 1 123 ? -0.598  12.172  -57.075  1.00 40.20  ? 123 LEU B CG    1 
ATOM   5016  C  CD1   . LEU B 1 123 ? -1.637  11.262  -56.440  1.00 38.26  ? 123 LEU B CD1   1 
ATOM   5017  C  CD2   . LEU B 1 123 ? 0.028   11.513  -58.289  1.00 40.28  ? 123 LEU B CD2   1 
ATOM   5018  N  N     . VAL B 1 124 ? -0.694  14.385  -54.085  1.00 46.58  ? 124 VAL B N     1 
ATOM   5019  C  CA    . VAL B 1 124 ? 0.192   14.885  -53.044  1.00 46.15  ? 124 VAL B CA    1 
ATOM   5020  C  C     . VAL B 1 124 ? 0.604   13.761  -52.105  1.00 42.42  ? 124 VAL B C     1 
ATOM   5021  O  O     . VAL B 1 124 ? -0.139  12.806  -51.894  1.00 45.71  ? 124 VAL B O     1 
ATOM   5022  C  CB    . VAL B 1 124 ? -0.469  16.028  -52.248  1.00 41.42  ? 124 VAL B CB    1 
ATOM   5023  C  CG1   . VAL B 1 124 ? -0.652  17.250  -53.132  1.00 38.75  ? 124 VAL B CG1   1 
ATOM   5024  C  CG2   . VAL B 1 124 ? -1.802  15.629  -51.617  1.00 40.64  ? 124 VAL B CG2   1 
ATOM   5025  N  N     . GLU B 1 125 ? 1.811   13.915  -51.547  1.00 42.24  ? 125 GLU B N     1 
ATOM   5026  C  CA    . GLU B 1 125 ? 2.286   13.093  -50.452  1.00 39.36  ? 125 GLU B CA    1 
ATOM   5027  C  C     . GLU B 1 125 ? 1.778   13.648  -49.121  1.00 36.70  ? 125 GLU B C     1 
ATOM   5028  O  O     . GLU B 1 125 ? 1.346   14.802  -49.026  1.00 41.98  ? 125 GLU B O     1 
ATOM   5029  C  CB    . GLU B 1 125 ? 3.814   13.041  -50.464  1.00 41.85  ? 125 GLU B CB    1 
ATOM   5030  C  CG    . GLU B 1 125 ? 4.403   12.411  -51.711  1.00 42.86  ? 125 GLU B CG    1 
ATOM   5031  C  CD    . GLU B 1 125 ? 5.906   12.246  -51.576  1.00 44.94  ? 125 GLU B CD    1 
ATOM   5032  O  OE1   . GLU B 1 125 ? 6.545   13.218  -51.165  1.00 39.48  ? 125 GLU B OE1   1 
ATOM   5033  O  OE2   . GLU B 1 125 ? 6.414   11.130  -51.811  1.00 49.61  ? 125 GLU B OE2   1 
ATOM   5034  N  N     . PRO B 1 126 ? 1.844   12.846  -48.035  1.00 36.93  ? 126 PRO B N     1 
ATOM   5035  C  CA    . PRO B 1 126 ? 1.286   13.236  -46.743  1.00 37.19  ? 126 PRO B CA    1 
ATOM   5036  C  C     . PRO B 1 126 ? 1.813   14.524  -46.116  1.00 41.52  ? 126 PRO B C     1 
ATOM   5037  O  O     . PRO B 1 126 ? 1.091   15.172  -45.352  1.00 36.90  ? 126 PRO B O     1 
ATOM   5038  C  CB    . PRO B 1 126 ? 1.660   12.051  -45.843  1.00 38.03  ? 126 PRO B CB    1 
ATOM   5039  C  CG    . PRO B 1 126 ? 1.736   10.879  -46.788  1.00 36.86  ? 126 PRO B CG    1 
ATOM   5040  C  CD    . PRO B 1 126 ? 2.363   11.475  -48.021  1.00 37.78  ? 126 PRO B CD    1 
ATOM   5041  N  N     . GLY B 1 127 ? 3.093   14.842  -46.362  1.00 39.92  ? 127 GLY B N     1 
ATOM   5042  C  CA    . GLY B 1 127 ? 3.699   16.021  -45.775  1.00 37.41  ? 127 GLY B CA    1 
ATOM   5043  C  C     . GLY B 1 127 ? 3.219   17.323  -46.417  1.00 39.73  ? 127 GLY B C     1 
ATOM   5044  O  O     . GLY B 1 127 ? 3.571   18.402  -45.954  1.00 37.87  ? 127 GLY B O     1 
ATOM   5045  N  N     . VAL B 1 128 ? 2.434   17.275  -47.502  1.00 38.29  ? 128 VAL B N     1 
ATOM   5046  C  CA    . VAL B 1 128 ? 2.055   18.543  -48.119  1.00 39.67  ? 128 VAL B CA    1 
ATOM   5047  C  C     . VAL B 1 128 ? 1.044   19.243  -47.218  1.00 45.76  ? 128 VAL B C     1 
ATOM   5048  O  O     . VAL B 1 128 ? -0.036  18.704  -46.984  1.00 43.22  ? 128 VAL B O     1 
ATOM   5049  C  CB    . VAL B 1 128 ? 1.498   18.395  -49.545  1.00 35.08  ? 128 VAL B CB    1 
ATOM   5050  C  CG1   . VAL B 1 128 ? 1.056   19.734  -50.110  1.00 36.87  ? 128 VAL B CG1   1 
ATOM   5051  C  CG2   . VAL B 1 128 ? 2.518   17.745  -50.464  1.00 38.69  ? 128 VAL B CG2   1 
ATOM   5052  N  N     . SER B 1 129 ? 1.397   20.457  -46.765  1.00 42.94  ? 129 SER B N     1 
ATOM   5053  C  CA    . SER B 1 129 ? 0.499   21.264  -45.960  1.00 38.46  ? 129 SER B CA    1 
ATOM   5054  C  C     . SER B 1 129 ? -0.423  22.059  -46.873  1.00 34.94  ? 129 SER B C     1 
ATOM   5055  O  O     . SER B 1 129 ? -0.138  22.240  -48.045  1.00 38.82  ? 129 SER B O     1 
ATOM   5056  C  CB    . SER B 1 129 ? 1.264   22.175  -45.016  1.00 38.86  ? 129 SER B CB    1 
ATOM   5057  O  OG    . SER B 1 129 ? 1.824   23.259  -45.727  1.00 40.77  ? 129 SER B OG    1 
ATOM   5058  N  N     . TYR B 1 130 ? -1.528  22.534  -46.304  1.00 36.24  ? 130 TYR B N     1 
ATOM   5059  C  CA    . TYR B 1 130 ? -2.430  23.442  -46.979  1.00 36.36  ? 130 TYR B CA    1 
ATOM   5060  C  C     . TYR B 1 130 ? -1.699  24.708  -47.422  1.00 37.27  ? 130 TYR B C     1 
ATOM   5061  O  O     . TYR B 1 130 ? -1.884  25.158  -48.554  1.00 35.53  ? 130 TYR B O     1 
ATOM   5062  C  CB    . TYR B 1 130 ? -3.606  23.755  -46.056  1.00 38.60  ? 130 TYR B CB    1 
ATOM   5063  C  CG    . TYR B 1 130 ? -4.511  22.574  -45.810  1.00 39.88  ? 130 TYR B CG    1 
ATOM   5064  C  CD1   . TYR B 1 130 ? -5.413  22.167  -46.781  1.00 41.91  ? 130 TYR B CD1   1 
ATOM   5065  C  CD2   . TYR B 1 130 ? -4.476  21.870  -44.618  1.00 39.28  ? 130 TYR B CD2   1 
ATOM   5066  C  CE1   . TYR B 1 130 ? -6.259  21.088  -46.581  1.00 42.26  ? 130 TYR B CE1   1 
ATOM   5067  C  CE2   . TYR B 1 130 ? -5.328  20.798  -44.392  1.00 43.24  ? 130 TYR B CE2   1 
ATOM   5068  C  CZ    . TYR B 1 130 ? -6.215  20.402  -45.384  1.00 42.05  ? 130 TYR B CZ    1 
ATOM   5069  O  OH    . TYR B 1 130 ? -7.056  19.346  -45.219  1.00 38.15  ? 130 TYR B OH    1 
ATOM   5070  N  N     . PHE B 1 131 ? -0.846  25.254  -46.553  1.00 40.66  ? 131 PHE B N     1 
ATOM   5071  C  CA    . PHE B 1 131 ? -0.027  26.408  -46.921  1.00 44.78  ? 131 PHE B CA    1 
ATOM   5072  C  C     . PHE B 1 131 ? 0.834   26.121  -48.146  1.00 38.70  ? 131 PHE B C     1 
ATOM   5073  O  O     . PHE B 1 131 ? 0.905   26.956  -49.050  1.00 40.98  ? 131 PHE B O     1 
ATOM   5074  C  CB    . PHE B 1 131 ? 0.865   26.856  -45.761  1.00 46.54  ? 131 PHE B CB    1 
ATOM   5075  C  CG    . PHE B 1 131 ? 0.133   27.680  -44.734  1.00 47.10  ? 131 PHE B CG    1 
ATOM   5076  C  CD1   . PHE B 1 131 ? -0.299  28.959  -45.045  1.00 48.77  ? 131 PHE B CD1   1 
ATOM   5077  C  CD2   . PHE B 1 131 ? -0.182  27.158  -43.490  1.00 47.52  ? 131 PHE B CD2   1 
ATOM   5078  C  CE1   . PHE B 1 131 ? -0.984  29.724  -44.113  1.00 46.98  ? 131 PHE B CE1   1 
ATOM   5079  C  CE2   . PHE B 1 131 ? -0.889  27.917  -42.570  1.00 48.07  ? 131 PHE B CE2   1 
ATOM   5080  C  CZ    . PHE B 1 131 ? -1.271  29.202  -42.878  1.00 44.64  ? 131 PHE B CZ    1 
ATOM   5081  N  N     . GLU B 1 132 ? 1.473   24.947  -48.184  1.00 40.54  ? 132 GLU B N     1 
ATOM   5082  C  CA    . GLU B 1 132 ? 2.389   24.629  -49.277  1.00 46.53  ? 132 GLU B CA    1 
ATOM   5083  C  C     . GLU B 1 132 ? 1.634   24.518  -50.613  1.00 43.41  ? 132 GLU B C     1 
ATOM   5084  O  O     . GLU B 1 132 ? 2.041   25.104  -51.611  1.00 40.31  ? 132 GLU B O     1 
ATOM   5085  C  CB    . GLU B 1 132 ? 3.143   23.331  -48.988  1.00 50.42  ? 132 GLU B CB    1 
ATOM   5086  C  CG    . GLU B 1 132 ? 4.062   23.385  -47.778  1.00 57.61  ? 132 GLU B CG    1 
ATOM   5087  C  CD    . GLU B 1 132 ? 4.669   22.037  -47.418  1.00 62.85  ? 132 GLU B CD    1 
ATOM   5088  O  OE1   . GLU B 1 132 ? 4.254   21.002  -48.004  1.00 65.84  ? 132 GLU B OE1   1 
ATOM   5089  O  OE2   . GLU B 1 132 ? 5.599   22.025  -46.602  1.00 77.83  ? 132 GLU B OE2   1 
ATOM   5090  N  N     . LEU B 1 133 ? 0.503   23.802  -50.625  1.00 40.71  ? 133 LEU B N     1 
ATOM   5091  C  CA    . LEU B 1 133 ? -0.273  23.623  -51.851  1.00 37.61  ? 133 LEU B CA    1 
ATOM   5092  C  C     . LEU B 1 133 ? -0.859  24.960  -52.291  1.00 39.93  ? 133 LEU B C     1 
ATOM   5093  O  O     . LEU B 1 133 ? -0.796  25.294  -53.469  1.00 43.02  ? 133 LEU B O     1 
ATOM   5094  C  CB    . LEU B 1 133 ? -1.348  22.559  -51.615  1.00 38.29  ? 133 LEU B CB    1 
ATOM   5095  C  CG    . LEU B 1 133 ? -2.300  22.267  -52.775  1.00 39.81  ? 133 LEU B CG    1 
ATOM   5096  C  CD1   . LEU B 1 133 ? -1.538  21.758  -53.982  1.00 40.23  ? 133 LEU B CD1   1 
ATOM   5097  C  CD2   . LEU B 1 133 ? -3.367  21.248  -52.359  1.00 38.42  ? 133 LEU B CD2   1 
ATOM   5098  N  N     . TYR B 1 134 ? -1.391  25.746  -51.343  1.00 42.08  ? 134 TYR B N     1 
ATOM   5099  C  CA    . TYR B 1 134 ? -1.859  27.093  -51.653  1.00 38.16  ? 134 TYR B CA    1 
ATOM   5100  C  C     . TYR B 1 134 ? -0.726  27.888  -52.303  1.00 40.35  ? 134 TYR B C     1 
ATOM   5101  O  O     . TYR B 1 134 ? -0.923  28.521  -53.338  1.00 44.18  ? 134 TYR B O     1 
ATOM   5102  C  CB    . TYR B 1 134 ? -2.370  27.806  -50.396  1.00 38.52  ? 134 TYR B CB    1 
ATOM   5103  C  CG    . TYR B 1 134 ? -2.939  29.185  -50.640  1.00 35.79  ? 134 TYR B CG    1 
ATOM   5104  C  CD1   . TYR B 1 134 ? -4.236  29.336  -51.107  1.00 35.77  ? 134 TYR B CD1   1 
ATOM   5105  C  CD2   . TYR B 1 134 ? -2.192  30.332  -50.418  1.00 36.40  ? 134 TYR B CD2   1 
ATOM   5106  C  CE1   . TYR B 1 134 ? -4.782  30.586  -51.362  1.00 36.27  ? 134 TYR B CE1   1 
ATOM   5107  C  CE2   . TYR B 1 134 ? -2.709  31.595  -50.696  1.00 43.42  ? 134 TYR B CE2   1 
ATOM   5108  C  CZ    . TYR B 1 134 ? -4.021  31.720  -51.142  1.00 44.65  ? 134 TYR B CZ    1 
ATOM   5109  O  OH    . TYR B 1 134 ? -4.616  32.927  -51.411  1.00 44.41  ? 134 TYR B OH    1 
ATOM   5110  N  N     . ASP B 1 135 ? 0.470   27.831  -51.697  1.00 41.69  ? 135 ASP B N     1 
ATOM   5111  C  CA    . ASP B 1 135 ? 1.588   28.648  -52.135  1.00 43.10  ? 135 ASP B CA    1 
ATOM   5112  C  C     . ASP B 1 135 ? 2.008   28.190  -53.531  1.00 45.62  ? 135 ASP B C     1 
ATOM   5113  O  O     . ASP B 1 135 ? 2.247   29.020  -54.400  1.00 38.41  ? 135 ASP B O     1 
ATOM   5114  C  CB    . ASP B 1 135 ? 2.730   28.660  -51.106  1.00 46.12  ? 135 ASP B CB    1 
ATOM   5115  C  CG    . ASP B 1 135 ? 2.465   29.529  -49.878  1.00 45.96  ? 135 ASP B CG    1 
ATOM   5116  O  OD1   . ASP B 1 135 ? 1.581   30.385  -49.946  1.00 51.23  ? 135 ASP B OD1   1 
ATOM   5117  O  OD2   . ASP B 1 135 ? 3.120   29.315  -48.851  1.00 53.05  ? 135 ASP B OD2   1 
ATOM   5118  N  N     . TYR B 1 136 ? 2.037   26.871  -53.754  1.00 44.30  ? 136 TYR B N     1 
ATOM   5119  C  CA    . TYR B 1 136 ? 2.433   26.334  -55.038  1.00 41.09  ? 136 TYR B CA    1 
ATOM   5120  C  C     . TYR B 1 136 ? 1.463   26.810  -56.118  1.00 45.69  ? 136 TYR B C     1 
ATOM   5121  O  O     . TYR B 1 136 ? 1.885   27.168  -57.215  1.00 42.98  ? 136 TYR B O     1 
ATOM   5122  C  CB    . TYR B 1 136 ? 2.544   24.809  -54.955  1.00 43.29  ? 136 TYR B CB    1 
ATOM   5123  C  CG    . TYR B 1 136 ? 2.844   24.133  -56.275  1.00 50.30  ? 136 TYR B CG    1 
ATOM   5124  C  CD1   . TYR B 1 136 ? 1.851   23.975  -57.233  1.00 47.60  ? 136 TYR B CD1   1 
ATOM   5125  C  CD2   . TYR B 1 136 ? 4.122   23.675  -56.583  1.00 49.87  ? 136 TYR B CD2   1 
ATOM   5126  C  CE1   . TYR B 1 136 ? 2.103   23.339  -58.435  1.00 53.43  ? 136 TYR B CE1   1 
ATOM   5127  C  CE2   . TYR B 1 136 ? 4.400   23.072  -57.797  1.00 52.85  ? 136 TYR B CE2   1 
ATOM   5128  C  CZ    . TYR B 1 136 ? 3.384   22.900  -58.723  1.00 59.80  ? 136 TYR B CZ    1 
ATOM   5129  O  OH    . TYR B 1 136 ? 3.600   22.304  -59.936  1.00 59.62  ? 136 TYR B OH    1 
ATOM   5130  N  N     . ILE B 1 137 ? 0.160   26.823  -55.814  1.00 43.18  ? 137 ILE B N     1 
ATOM   5131  C  CA    . ILE B 1 137 ? -0.854  27.198  -56.792  1.00 40.89  ? 137 ILE B CA    1 
ATOM   5132  C  C     . ILE B 1 137 ? -0.768  28.691  -57.120  1.00 44.81  ? 137 ILE B C     1 
ATOM   5133  O  O     . ILE B 1 137 ? -0.866  29.074  -58.293  1.00 41.21  ? 137 ILE B O     1 
ATOM   5134  C  CB    . ILE B 1 137 ? -2.257  26.809  -56.288  1.00 40.78  ? 137 ILE B CB    1 
ATOM   5135  C  CG1   . ILE B 1 137 ? -2.490  25.304  -56.444  1.00 41.01  ? 137 ILE B CG1   1 
ATOM   5136  C  CG2   . ILE B 1 137 ? -3.336  27.638  -56.954  1.00 35.65  ? 137 ILE B CG2   1 
ATOM   5137  C  CD1   . ILE B 1 137 ? -3.660  24.768  -55.640  1.00 39.98  ? 137 ILE B CD1   1 
ATOM   5138  N  N     . GLN B 1 138 ? -0.601  29.530  -56.096  1.00 42.91  ? 138 GLN B N     1 
ATOM   5139  C  CA    . GLN B 1 138 ? -0.475  30.965  -56.316  1.00 48.03  ? 138 GLN B CA    1 
ATOM   5140  C  C     . GLN B 1 138 ? 0.775   31.278  -57.136  1.00 46.77  ? 138 GLN B C     1 
ATOM   5141  O  O     . GLN B 1 138 ? 0.724   32.139  -57.995  1.00 54.20  ? 138 GLN B O     1 
ATOM   5142  C  CB    . GLN B 1 138 ? -0.338  31.759  -55.015  1.00 50.25  ? 138 GLN B CB    1 
ATOM   5143  C  CG    . GLN B 1 138 ? -1.525  31.631  -54.087  1.00 54.69  ? 138 GLN B CG    1 
ATOM   5144  C  CD    . GLN B 1 138 ? -2.824  31.937  -54.783  1.00 57.51  ? 138 GLN B CD    1 
ATOM   5145  O  OE1   . GLN B 1 138 ? -3.065  33.061  -55.213  1.00 64.17  ? 138 GLN B OE1   1 
ATOM   5146  N  NE2   . GLN B 1 138 ? -3.676  30.933  -54.890  1.00 56.69  ? 138 GLN B NE2   1 
ATOM   5147  N  N     . GLU B 1 139 ? 1.894   30.616  -56.839  1.00 47.51  ? 139 GLU B N     1 
ATOM   5148  C  CA    . GLU B 1 139 ? 3.148   30.872  -57.533  1.00 54.29  ? 139 GLU B CA    1 
ATOM   5149  C  C     . GLU B 1 139 ? 2.999   30.508  -59.005  1.00 56.30  ? 139 GLU B C     1 
ATOM   5150  O  O     . GLU B 1 139 ? 3.555   31.163  -59.866  1.00 55.34  ? 139 GLU B O     1 
ATOM   5151  C  CB    . GLU B 1 139 ? 4.289   30.041  -56.948  1.00 58.39  ? 139 GLU B CB    1 
ATOM   5152  C  CG    . GLU B 1 139 ? 5.016   30.687  -55.790  1.00 69.77  ? 139 GLU B CG    1 
ATOM   5153  C  CD    . GLU B 1 139 ? 6.008   29.749  -55.116  1.00 84.00  ? 139 GLU B CD    1 
ATOM   5154  O  OE1   . GLU B 1 139 ? 6.132   29.802  -53.874  1.00 83.75  ? 139 GLU B OE1   1 
ATOM   5155  O  OE2   . GLU B 1 139 ? 6.635   28.938  -55.835  1.00 94.74  ? 139 GLU B OE2   1 
ATOM   5156  N  N     . LYS B 1 140 ? 2.249   29.444  -59.289  1.00 55.32  ? 140 LYS B N     1 
ATOM   5157  C  CA    . LYS B 1 140 ? 2.084   28.998  -60.653  1.00 52.33  ? 140 LYS B CA    1 
ATOM   5158  C  C     . LYS B 1 140 ? 0.995   29.791  -61.368  1.00 46.49  ? 140 LYS B C     1 
ATOM   5159  O  O     . LYS B 1 140 ? 0.824   29.646  -62.567  1.00 55.04  ? 140 LYS B O     1 
ATOM   5160  C  CB    . LYS B 1 140 ? 1.797   27.498  -60.666  1.00 51.73  ? 140 LYS B CB    1 
ATOM   5161  C  CG    . LYS B 1 140 ? 2.945   26.637  -60.163  1.00 58.50  ? 140 LYS B CG    1 
ATOM   5162  C  CD    . LYS B 1 140 ? 4.231   26.822  -60.923  1.00 67.10  ? 140 LYS B CD    1 
ATOM   5163  C  CE    . LYS B 1 140 ? 5.301   25.844  -60.492  1.00 75.48  ? 140 LYS B CE    1 
ATOM   5164  N  NZ    . LYS B 1 140 ? 6.589   26.137  -61.161  1.00 81.89  ? 140 LYS B NZ    1 
ATOM   5165  N  N     . GLY B 1 141 ? 0.234   30.611  -60.653  1.00 42.46  ? 141 GLY B N     1 
ATOM   5166  C  CA    . GLY B 1 141 ? -0.917  31.251  -61.254  1.00 44.14  ? 141 GLY B CA    1 
ATOM   5167  C  C     . GLY B 1 141 ? -1.958  30.255  -61.780  1.00 47.84  ? 141 GLY B C     1 
ATOM   5168  O  O     . GLY B 1 141 ? -2.632  30.542  -62.759  1.00 52.82  ? 141 GLY B O     1 
ATOM   5169  N  N     . LEU B 1 142 ? -2.100  29.084  -61.151  1.00 41.79  ? 142 LEU B N     1 
ATOM   5170  C  CA    . LEU B 1 142 ? -3.158  28.152  -61.523  1.00 44.04  ? 142 LEU B CA    1 
ATOM   5171  C  C     . LEU B 1 142 ? -4.517  28.645  -61.013  1.00 43.05  ? 142 LEU B C     1 
ATOM   5172  O  O     . LEU B 1 142 ? -4.608  29.209  -59.932  1.00 43.17  ? 142 LEU B O     1 
ATOM   5173  C  CB    . LEU B 1 142 ? -2.799  26.778  -60.956  1.00 41.35  ? 142 LEU B CB    1 
ATOM   5174  C  CG    . LEU B 1 142 ? -1.458  26.230  -61.435  1.00 45.65  ? 142 LEU B CG    1 
ATOM   5175  C  CD1   . LEU B 1 142 ? -1.247  24.811  -60.926  1.00 46.96  ? 142 LEU B CD1   1 
ATOM   5176  C  CD2   . LEU B 1 142 ? -1.339  26.273  -62.964  1.00 45.45  ? 142 LEU B CD2   1 
ATOM   5177  N  N     . LYS B 1 143 ? -5.586  28.413  -61.791  1.00 48.25  ? 143 LYS B N     1 
ATOM   5178  C  CA    . LYS B 1 143 ? -6.906  28.960  -61.495  1.00 50.71  ? 143 LYS B CA    1 
ATOM   5179  C  C     . LYS B 1 143 ? -7.722  27.952  -60.687  1.00 44.77  ? 143 LYS B C     1 
ATOM   5180  O  O     . LYS B 1 143 ? -8.776  27.500  -61.128  1.00 42.78  ? 143 LYS B O     1 
ATOM   5181  C  CB    . LYS B 1 143 ? -7.650  29.262  -62.799  1.00 54.82  ? 143 LYS B CB    1 
ATOM   5182  C  CG    . LYS B 1 143 ? -7.020  30.317  -63.689  1.00 62.81  ? 143 LYS B CG    1 
ATOM   5183  C  CD    . LYS B 1 143 ? -7.200  31.713  -63.175  1.00 75.40  ? 143 LYS B CD    1 
ATOM   5184  C  CE    . LYS B 1 143 ? -6.752  32.752  -64.180  1.00 90.78  ? 143 LYS B CE    1 
ATOM   5185  N  NZ    . LYS B 1 143 ? -7.012  34.121  -63.681  1.00 101.82 ? 143 LYS B NZ    1 
ATOM   5186  N  N     . LEU B 1 144 ? -7.188  27.561  -59.535  1.00 40.94  ? 144 LEU B N     1 
ATOM   5187  C  CA    . LEU B 1 144 ? -7.758  26.517  -58.703  1.00 42.24  ? 144 LEU B CA    1 
ATOM   5188  C  C     . LEU B 1 144 ? -7.841  27.051  -57.295  1.00 41.04  ? 144 LEU B C     1 
ATOM   5189  O  O     . LEU B 1 144 ? -6.916  27.736  -56.890  1.00 41.25  ? 144 LEU B O     1 
ATOM   5190  C  CB    . LEU B 1 144 ? -6.831  25.308  -58.701  1.00 39.92  ? 144 LEU B CB    1 
ATOM   5191  C  CG    . LEU B 1 144 ? -6.684  24.617  -60.039  1.00 40.26  ? 144 LEU B CG    1 
ATOM   5192  C  CD1   . LEU B 1 144 ? -5.612  23.552  -59.968  1.00 42.99  ? 144 LEU B CD1   1 
ATOM   5193  C  CD2   . LEU B 1 144 ? -8.017  24.051  -60.479  1.00 41.24  ? 144 LEU B CD2   1 
ATOM   5194  N  N     . TRP B 1 145 ? -8.925  26.749  -56.579  1.00 39.75  ? 145 TRP B N     1 
ATOM   5195  C  CA    . TRP B 1 145 ? -8.961  26.958  -55.137  1.00 37.44  ? 145 TRP B CA    1 
ATOM   5196  C  C     . TRP B 1 145 ? -8.738  25.627  -54.415  1.00 39.57  ? 145 TRP B C     1 
ATOM   5197  O  O     . TRP B 1 145 ? -9.033  24.559  -54.953  1.00 39.35  ? 145 TRP B O     1 
ATOM   5198  C  CB    . TRP B 1 145 ? -10.282 27.593  -54.724  1.00 38.78  ? 145 TRP B CB    1 
ATOM   5199  C  CG    . TRP B 1 145 ? -10.440 29.030  -55.115  1.00 42.03  ? 145 TRP B CG    1 
ATOM   5200  C  CD1   . TRP B 1 145 ? -9.560  29.807  -55.817  1.00 43.17  ? 145 TRP B CD1   1 
ATOM   5201  C  CD2   . TRP B 1 145 ? -11.584 29.865  -54.837  1.00 43.62  ? 145 TRP B CD2   1 
ATOM   5202  N  NE1   . TRP B 1 145 ? -10.065 31.075  -55.964  1.00 44.07  ? 145 TRP B NE1   1 
ATOM   5203  C  CE2   . TRP B 1 145 ? -11.310 31.136  -55.389  1.00 47.81  ? 145 TRP B CE2   1 
ATOM   5204  C  CE3   . TRP B 1 145 ? -12.814 29.659  -54.191  1.00 51.28  ? 145 TRP B CE3   1 
ATOM   5205  C  CZ2   . TRP B 1 145 ? -12.213 32.200  -55.294  1.00 47.73  ? 145 TRP B CZ2   1 
ATOM   5206  C  CZ3   . TRP B 1 145 ? -13.709 30.708  -54.109  1.00 44.76  ? 145 TRP B CZ3   1 
ATOM   5207  C  CH2   . TRP B 1 145 ? -13.404 31.960  -54.647  1.00 44.77  ? 145 TRP B CH2   1 
ATOM   5208  N  N     . ILE B 1 146 ? -8.168  25.689  -53.201  1.00 35.26  ? 146 ILE B N     1 
ATOM   5209  C  CA    . ILE B 1 146 ? -8.118  24.529  -52.340  1.00 34.03  ? 146 ILE B CA    1 
ATOM   5210  C  C     . ILE B 1 146 ? -9.230  24.708  -51.316  1.00 37.17  ? 146 ILE B C     1 
ATOM   5211  O  O     . ILE B 1 146 ? -9.882  25.759  -51.283  1.00 34.57  ? 146 ILE B O     1 
ATOM   5212  C  CB    . ILE B 1 146 ? -6.726  24.343  -51.702  1.00 36.61  ? 146 ILE B CB    1 
ATOM   5213  C  CG1   . ILE B 1 146 ? -6.348  25.474  -50.745  1.00 37.57  ? 146 ILE B CG1   1 
ATOM   5214  C  CG2   . ILE B 1 146 ? -5.678  24.164  -52.789  1.00 38.55  ? 146 ILE B CG2   1 
ATOM   5215  C  CD1   . ILE B 1 146 ? -5.345  25.036  -49.710  1.00 39.97  ? 146 ILE B CD1   1 
ATOM   5216  N  N     . ASP B 1 147 ? -9.434  23.671  -50.500  1.00 35.21  ? 147 ASP B N     1 
ATOM   5217  C  CA    . ASP B 1 147 ? -10.396 23.750  -49.414  1.00 35.82  ? 147 ASP B CA    1 
ATOM   5218  C  C     . ASP B 1 147 ? -9.667  23.475  -48.094  1.00 34.35  ? 147 ASP B C     1 
ATOM   5219  O  O     . ASP B 1 147 ? -9.085  22.400  -47.920  1.00 33.48  ? 147 ASP B O     1 
ATOM   5220  C  CB    . ASP B 1 147 ? -11.565 22.797  -49.662  1.00 35.31  ? 147 ASP B CB    1 
ATOM   5221  C  CG    . ASP B 1 147 ? -12.664 23.019  -48.646  1.00 36.47  ? 147 ASP B CG    1 
ATOM   5222  O  OD1   . ASP B 1 147 ? -12.422 22.673  -47.469  1.00 38.67  ? 147 ASP B OD1   1 
ATOM   5223  O  OD2   . ASP B 1 147 ? -13.735 23.561  -49.045  1.00 35.74  ? 147 ASP B OD2   1 
ATOM   5224  N  N     . VAL B 1 148 ? -9.689  24.472  -47.195  1.00 34.81  ? 148 VAL B N     1 
ATOM   5225  C  CA    . VAL B 1 148 ? -8.852  24.487  -46.002  1.00 38.45  ? 148 VAL B CA    1 
ATOM   5226  C  C     . VAL B 1 148 ? -9.705  24.321  -44.748  1.00 38.49  ? 148 VAL B C     1 
ATOM   5227  O  O     . VAL B 1 148 ? -10.764 24.934  -44.608  1.00 37.85  ? 148 VAL B O     1 
ATOM   5228  C  CB    . VAL B 1 148 ? -8.003  25.770  -45.894  1.00 38.34  ? 148 VAL B CB    1 
ATOM   5229  C  CG1   . VAL B 1 148 ? -7.083  25.915  -47.088  1.00 41.61  ? 148 VAL B CG1   1 
ATOM   5230  C  CG2   . VAL B 1 148 ? -8.837  27.035  -45.713  1.00 37.15  ? 148 VAL B CG2   1 
ATOM   5231  N  N     . PRO B 1 149 ? -9.220  23.544  -43.761  1.00 38.67  ? 149 PRO B N     1 
ATOM   5232  C  CA    . PRO B 1 149 ? -9.773  23.587  -42.414  1.00 42.82  ? 149 PRO B CA    1 
ATOM   5233  C  C     . PRO B 1 149 ? -9.242  24.831  -41.707  1.00 42.83  ? 149 PRO B C     1 
ATOM   5234  O  O     . PRO B 1 149 ? -8.428  25.569  -42.263  1.00 43.40  ? 149 PRO B O     1 
ATOM   5235  C  CB    . PRO B 1 149 ? -9.236  22.289  -41.807  1.00 41.48  ? 149 PRO B CB    1 
ATOM   5236  C  CG    . PRO B 1 149 ? -7.847  22.184  -42.416  1.00 42.06  ? 149 PRO B CG    1 
ATOM   5237  C  CD    . PRO B 1 149 ? -8.069  22.632  -43.852  1.00 39.20  ? 149 PRO B CD    1 
ATOM   5238  N  N     . ASP B 1 150 ? -9.655  25.025  -40.458  1.00 49.75  ? 150 ASP B N     1 
ATOM   5239  C  CA    . ASP B 1 150 ? -9.443  26.311  -39.810  1.00 59.45  ? 150 ASP B CA    1 
ATOM   5240  C  C     . ASP B 1 150 ? -7.988  26.512  -39.379  1.00 55.47  ? 150 ASP B C     1 
ATOM   5241  O  O     . ASP B 1 150 ? -7.633  27.639  -39.041  1.00 64.01  ? 150 ASP B O     1 
ATOM   5242  C  CB    . ASP B 1 150 ? -10.457 26.533  -38.690  1.00 63.46  ? 150 ASP B CB    1 
ATOM   5243  C  CG    . ASP B 1 150 ? -11.709 27.248  -39.161  1.00 66.65  ? 150 ASP B CG    1 
ATOM   5244  O  OD1   . ASP B 1 150 ? -11.579 28.188  -39.992  1.00 73.72  ? 150 ASP B OD1   1 
ATOM   5245  O  OD2   . ASP B 1 150 ? -12.795 26.892  -38.670  1.00 72.55  ? 150 ASP B OD2   1 
ATOM   5246  N  N     . ASN B 1 151 ? -7.139  25.476  -39.479  1.00 61.12  ? 151 ASN B N     1 
ATOM   5247  C  CA    . ASN B 1 151 ? -5.692  25.676  -39.437  1.00 68.74  ? 151 ASN B CA    1 
ATOM   5248  C  C     . ASN B 1 151 ? -5.004  25.166  -40.710  1.00 66.65  ? 151 ASN B C     1 
ATOM   5249  O  O     . ASN B 1 151 ? -5.037  23.971  -41.030  1.00 72.10  ? 151 ASN B O     1 
ATOM   5250  C  CB    . ASN B 1 151 ? -5.043  24.945  -38.263  1.00 77.16  ? 151 ASN B CB    1 
ATOM   5251  C  CG    . ASN B 1 151 ? -4.833  23.471  -38.538  1.00 75.86  ? 151 ASN B CG    1 
ATOM   5252  O  OD1   . ASN B 1 151 ? -5.800  22.767  -38.830  1.00 73.46  ? 151 ASN B OD1   1 
ATOM   5253  N  ND2   . ASN B 1 151 ? -3.584  23.019  -38.493  1.00 70.33  ? 151 ASN B ND2   1 
ATOM   5254  N  N     . GLY B 1 152 ? -4.254  26.054  -41.366  1.00 55.39  ? 152 GLY B N     1 
ATOM   5255  C  CA    . GLY B 1 152 ? -3.601  25.713  -42.617  1.00 56.47  ? 152 GLY B CA    1 
ATOM   5256  C  C     . GLY B 1 152 ? -2.353  24.859  -42.432  1.00 64.64  ? 152 GLY B C     1 
ATOM   5257  O  O     . GLY B 1 152 ? -1.718  24.474  -43.432  1.00 56.26  ? 152 GLY B O     1 
ATOM   5258  N  N     . TRP B 1 153 ? -1.982  24.579  -41.165  1.00 61.42  ? 153 TRP B N     1 
ATOM   5259  C  CA    . TRP B 1 153 ? -0.750  23.836  -40.948  1.00 65.66  ? 153 TRP B CA    1 
ATOM   5260  C  C     . TRP B 1 153 ? -0.992  22.335  -41.090  1.00 54.29  ? 153 TRP B C     1 
ATOM   5261  O  O     . TRP B 1 153 ? -0.040  21.558  -41.104  1.00 67.79  ? 153 TRP B O     1 
ATOM   5262  C  CB    . TRP B 1 153 ? -0.048  24.199  -39.625  1.00 71.63  ? 153 TRP B CB    1 
ATOM   5263  C  CG    . TRP B 1 153 ? 0.890   25.373  -39.715  1.00 74.88  ? 153 TRP B CG    1 
ATOM   5264  C  CD1   . TRP B 1 153 ? 0.966   26.409  -38.829  1.00 72.05  ? 153 TRP B CD1   1 
ATOM   5265  C  CD2   . TRP B 1 153 ? 1.896   25.635  -40.727  1.00 82.72  ? 153 TRP B CD2   1 
ATOM   5266  N  NE1   . TRP B 1 153 ? 1.934   27.299  -39.219  1.00 78.81  ? 153 TRP B NE1   1 
ATOM   5267  C  CE2   . TRP B 1 153 ? 2.525   26.853  -40.376  1.00 85.53  ? 153 TRP B CE2   1 
ATOM   5268  C  CE3   . TRP B 1 153 ? 2.328   24.978  -41.896  1.00 83.50  ? 153 TRP B CE3   1 
ATOM   5269  C  CZ2   . TRP B 1 153 ? 3.547   27.417  -41.150  1.00 88.29  ? 153 TRP B CZ2   1 
ATOM   5270  C  CZ3   . TRP B 1 153 ? 3.339   25.532  -42.658  1.00 83.14  ? 153 TRP B CZ3   1 
ATOM   5271  C  CH2   . TRP B 1 153 ? 3.941   26.739  -42.285  1.00 86.33  ? 153 TRP B CH2   1 
ATOM   5272  N  N     . GLY B 1 154 ? -2.245  21.918  -41.237  1.00 48.08  ? 154 GLY B N     1 
ATOM   5273  C  CA    . GLY B 1 154 ? -2.513  20.500  -41.425  1.00 44.86  ? 154 GLY B CA    1 
ATOM   5274  C  C     . GLY B 1 154 ? -2.081  19.963  -42.792  1.00 41.66  ? 154 GLY B C     1 
ATOM   5275  O  O     . GLY B 1 154 ? -1.654  20.687  -43.697  1.00 44.66  ? 154 GLY B O     1 
ATOM   5276  N  N     . SER B 1 155 ? -2.188  18.641  -42.901  1.00 41.27  ? 155 SER B N     1 
ATOM   5277  C  CA    . SER B 1 155 ? -1.904  17.878  -44.099  1.00 36.56  ? 155 SER B CA    1 
ATOM   5278  C  C     . SER B 1 155 ? -3.172  17.786  -44.948  1.00 42.12  ? 155 SER B C     1 
ATOM   5279  O  O     . SER B 1 155 ? -4.242  17.416  -44.469  1.00 40.53  ? 155 SER B O     1 
ATOM   5280  C  CB    . SER B 1 155 ? -1.433  16.491  -43.714  1.00 36.59  ? 155 SER B CB    1 
ATOM   5281  O  OG    . SER B 1 155 ? -1.428  15.605  -44.840  1.00 37.36  ? 155 SER B OG    1 
ATOM   5282  N  N     . VAL B 1 156 ? -3.019  18.072  -46.230  1.00 42.43  ? 156 VAL B N     1 
ATOM   5283  C  CA    . VAL B 1 156 ? -4.045  17.822  -47.219  1.00 41.50  ? 156 VAL B CA    1 
ATOM   5284  C  C     . VAL B 1 156 ? -4.499  16.367  -47.124  1.00 40.44  ? 156 VAL B C     1 
ATOM   5285  O  O     . VAL B 1 156 ? -5.708  16.095  -47.152  1.00 39.42  ? 156 VAL B O     1 
ATOM   5286  C  CB    . VAL B 1 156 ? -3.534  18.192  -48.615  1.00 37.96  ? 156 VAL B CB    1 
ATOM   5287  C  CG1   . VAL B 1 156 ? -4.604  17.955  -49.671  1.00 44.97  ? 156 VAL B CG1   1 
ATOM   5288  C  CG2   . VAL B 1 156 ? -3.052  19.630  -48.649  1.00 39.56  ? 156 VAL B CG2   1 
ATOM   5289  N  N     . VAL B 1 157 ? -3.527  15.473  -46.933  1.00 36.91  ? 157 VAL B N     1 
ATOM   5290  C  CA    . VAL B 1 157 ? -3.781  14.042  -46.880  1.00 40.23  ? 157 VAL B CA    1 
ATOM   5291  C  C     . VAL B 1 157 ? -4.397  13.674  -45.536  1.00 38.70  ? 157 VAL B C     1 
ATOM   5292  O  O     . VAL B 1 157 ? -5.504  13.124  -45.481  1.00 38.90  ? 157 VAL B O     1 
ATOM   5293  C  CB    . VAL B 1 157 ? -2.512  13.212  -47.151  1.00 38.56  ? 157 VAL B CB    1 
ATOM   5294  C  CG1   . VAL B 1 157 ? -2.746  11.722  -46.900  1.00 39.50  ? 157 VAL B CG1   1 
ATOM   5295  C  CG2   . VAL B 1 157 ? -2.010  13.436  -48.563  1.00 40.54  ? 157 VAL B CG2   1 
ATOM   5296  N  N     . GLY B 1 158 ? -3.658  13.950  -44.460  1.00 38.37  ? 158 GLY B N     1 
ATOM   5297  C  CA    . GLY B 1 158 ? -4.030  13.517  -43.122  1.00 37.76  ? 158 GLY B CA    1 
ATOM   5298  C  C     . GLY B 1 158 ? -5.412  14.026  -42.712  1.00 37.23  ? 158 GLY B C     1 
ATOM   5299  O  O     . GLY B 1 158 ? -6.198  13.301  -42.128  1.00 34.60  ? 158 GLY B O     1 
ATOM   5300  N  N     . ASN B 1 159 ? -5.699  15.289  -43.022  1.00 37.48  ? 159 ASN B N     1 
ATOM   5301  C  CA    . ASN B 1 159 ? -6.972  15.872  -42.666  1.00 38.58  ? 159 ASN B CA    1 
ATOM   5302  C  C     . ASN B 1 159 ? -8.088  15.105  -43.377  1.00 40.84  ? 159 ASN B C     1 
ATOM   5303  O  O     . ASN B 1 159 ? -9.103  14.806  -42.775  1.00 40.93  ? 159 ASN B O     1 
ATOM   5304  C  CB    . ASN B 1 159 ? -7.031  17.367  -42.985  1.00 37.34  ? 159 ASN B CB    1 
ATOM   5305  C  CG    . ASN B 1 159 ? -8.410  17.934  -42.719  1.00 41.70  ? 159 ASN B CG    1 
ATOM   5306  O  OD1   . ASN B 1 159 ? -9.309  17.843  -43.547  1.00 41.16  ? 159 ASN B OD1   1 
ATOM   5307  N  ND2   . ASN B 1 159 ? -8.590  18.537  -41.563  1.00 45.66  ? 159 ASN B ND2   1 
ATOM   5308  N  N     . ALA B 1 160 ? -7.894  14.798  -44.661  1.00 39.29  ? 160 ALA B N     1 
ATOM   5309  C  CA    . ALA B 1 160 ? -8.904  14.110  -45.441  1.00 41.78  ? 160 ALA B CA    1 
ATOM   5310  C  C     . ALA B 1 160 ? -9.144  12.711  -44.874  1.00 39.65  ? 160 ALA B C     1 
ATOM   5311  O  O     . ALA B 1 160 ? -10.292 12.280  -44.746  1.00 33.75  ? 160 ALA B O     1 
ATOM   5312  C  CB    . ALA B 1 160 ? -8.484  14.067  -46.886  1.00 43.77  ? 160 ALA B CB    1 
ATOM   5313  N  N     . LEU B 1 161 ? -8.063  12.028  -44.483  1.00 36.65  ? 161 LEU B N     1 
ATOM   5314  C  CA    . LEU B 1 161 ? -8.154  10.652  -44.017  1.00 38.78  ? 161 LEU B CA    1 
ATOM   5315  C  C     . LEU B 1 161 ? -8.879  10.616  -42.686  1.00 37.86  ? 161 LEU B C     1 
ATOM   5316  O  O     . LEU B 1 161 ? -9.417  9.580   -42.343  1.00 34.28  ? 161 LEU B O     1 
ATOM   5317  C  CB    . LEU B 1 161 ? -6.768  10.021  -43.872  1.00 38.53  ? 161 LEU B CB    1 
ATOM   5318  C  CG    . LEU B 1 161 ? -6.044  9.742   -45.185  1.00 37.19  ? 161 LEU B CG    1 
ATOM   5319  C  CD1   . LEU B 1 161 ? -4.696  9.100   -44.915  1.00 39.91  ? 161 LEU B CD1   1 
ATOM   5320  C  CD2   . LEU B 1 161 ? -6.878  8.853   -46.084  1.00 41.63  ? 161 LEU B CD2   1 
ATOM   5321  N  N     . ASP B 1 162 ? -8.913  11.752  -41.972  1.00 36.80  ? 162 ASP B N     1 
ATOM   5322  C  CA    . ASP B 1 162 ? -9.611  11.823  -40.703  1.00 36.89  ? 162 ASP B CA    1 
ATOM   5323  C  C     . ASP B 1 162 ? -11.036 12.367  -40.869  1.00 35.94  ? 162 ASP B C     1 
ATOM   5324  O  O     . ASP B 1 162 ? -11.653 12.724  -39.869  1.00 33.89  ? 162 ASP B O     1 
ATOM   5325  C  CB    . ASP B 1 162 ? -8.817  12.660  -39.704  1.00 39.01  ? 162 ASP B CB    1 
ATOM   5326  C  CG    . ASP B 1 162 ? -9.032  12.201  -38.274  1.00 49.53  ? 162 ASP B CG    1 
ATOM   5327  O  OD1   . ASP B 1 162 ? -9.066  10.952  -38.057  1.00 46.31  ? 162 ASP B OD1   1 
ATOM   5328  O  OD2   . ASP B 1 162 ? -9.150  13.084  -37.388  1.00 53.72  ? 162 ASP B OD2   1 
ATOM   5329  N  N     . HIS B 1 163 ? -11.533 12.424  -42.120  1.00 33.53  ? 163 HIS B N     1 
ATOM   5330  C  CA    . HIS B 1 163 ? -12.874 12.870  -42.474  1.00 36.78  ? 163 HIS B CA    1 
ATOM   5331  C  C     . HIS B 1 163 ? -13.011 14.360  -42.147  1.00 40.30  ? 163 HIS B C     1 
ATOM   5332  O  O     . HIS B 1 163 ? -14.081 14.844  -41.794  1.00 32.99  ? 163 HIS B O     1 
ATOM   5333  C  CB    . HIS B 1 163 ? -13.950 11.953  -41.875  1.00 33.72  ? 163 HIS B CB    1 
ATOM   5334  C  CG    . HIS B 1 163 ? -13.862 10.514  -42.296  1.00 35.04  ? 163 HIS B CG    1 
ATOM   5335  N  ND1   . HIS B 1 163 ? -14.485 9.494   -41.606  1.00 36.39  ? 163 HIS B ND1   1 
ATOM   5336  C  CD2   . HIS B 1 163 ? -13.182 9.916   -43.285  1.00 36.28  ? 163 HIS B CD2   1 
ATOM   5337  C  CE1   . HIS B 1 163 ? -14.203 8.323   -42.195  1.00 38.16  ? 163 HIS B CE1   1 
ATOM   5338  N  NE2   . HIS B 1 163 ? -13.432 8.557   -43.236  1.00 36.85  ? 163 HIS B NE2   1 
ATOM   5339  N  N     . GLY B 1 164 ? -11.914 15.103  -42.330  1.00 39.88  ? 164 GLY B N     1 
ATOM   5340  C  CA    . GLY B 1 164 ? -11.895 16.519  -42.006  1.00 36.06  ? 164 GLY B CA    1 
ATOM   5341  C  C     . GLY B 1 164 ? -12.678 17.336  -43.025  1.00 38.54  ? 164 GLY B C     1 
ATOM   5342  O  O     . GLY B 1 164 ? -13.052 16.825  -44.098  1.00 34.12  ? 164 GLY B O     1 
ATOM   5343  N  N     . ILE B 1 165 ? -12.920 18.605  -42.661  1.00 39.34  ? 165 ILE B N     1 
ATOM   5344  C  CA    . ILE B 1 165 ? -13.795 19.468  -43.441  1.00 41.64  ? 165 ILE B CA    1 
ATOM   5345  C  C     . ILE B 1 165 ? -13.208 20.866  -43.572  1.00 42.01  ? 165 ILE B C     1 
ATOM   5346  O  O     . ILE B 1 165 ? -12.380 21.261  -42.763  1.00 43.32  ? 165 ILE B O     1 
ATOM   5347  C  CB    . ILE B 1 165 ? -15.178 19.584  -42.786  1.00 42.92  ? 165 ILE B CB    1 
ATOM   5348  C  CG1   . ILE B 1 165 ? -15.118 20.436  -41.515  1.00 51.30  ? 165 ILE B CG1   1 
ATOM   5349  C  CG2   . ILE B 1 165 ? -15.799 18.215  -42.562  1.00 43.27  ? 165 ILE B CG2   1 
ATOM   5350  C  CD1   . ILE B 1 165 ? -16.443 20.505  -40.765  1.00 60.68  ? 165 ILE B CD1   1 
ATOM   5351  N  N     . GLY B 1 166 ? -13.731 21.622  -44.547  1.00 39.87  ? 166 GLY B N     1 
ATOM   5352  C  CA    . GLY B 1 166 ? -13.507 23.057  -44.680  1.00 35.27  ? 166 GLY B CA    1 
ATOM   5353  C  C     . GLY B 1 166 ? -14.779 23.749  -45.164  1.00 37.97  ? 166 GLY B C     1 
ATOM   5354  O  O     . GLY B 1 166 ? -15.879 23.270  -44.910  1.00 38.79  ? 166 GLY B O     1 
ATOM   5355  N  N     . TYR B 1 167 ? -14.646 24.891  -45.837  1.00 36.44  ? 167 TYR B N     1 
ATOM   5356  C  CA    . TYR B 1 167 ? -15.731 25.852  -45.851  1.00 37.06  ? 167 TYR B CA    1 
ATOM   5357  C  C     . TYR B 1 167 ? -15.995 26.365  -47.254  1.00 38.03  ? 167 TYR B C     1 
ATOM   5358  O  O     . TYR B 1 167 ? -16.640 27.396  -47.394  1.00 43.98  ? 167 TYR B O     1 
ATOM   5359  C  CB    . TYR B 1 167 ? -15.408 26.978  -44.866  1.00 40.84  ? 167 TYR B CB    1 
ATOM   5360  C  CG    . TYR B 1 167 ? -15.241 26.419  -43.484  1.00 41.46  ? 167 TYR B CG    1 
ATOM   5361  C  CD1   . TYR B 1 167 ? -16.336 25.947  -42.776  1.00 44.13  ? 167 TYR B CD1   1 
ATOM   5362  C  CD2   . TYR B 1 167 ? -13.979 26.183  -42.975  1.00 42.31  ? 167 TYR B CD2   1 
ATOM   5363  C  CE1   . TYR B 1 167 ? -16.183 25.349  -41.534  1.00 48.42  ? 167 TYR B CE1   1 
ATOM   5364  C  CE2   . TYR B 1 167 ? -13.808 25.584  -41.743  1.00 45.88  ? 167 TYR B CE2   1 
ATOM   5365  C  CZ    . TYR B 1 167 ? -14.912 25.161  -41.020  1.00 50.05  ? 167 TYR B CZ    1 
ATOM   5366  O  OH    . TYR B 1 167 ? -14.732 24.564  -39.794  1.00 55.58  ? 167 TYR B OH    1 
ATOM   5367  N  N     . THR B 1 168 ? -15.530 25.635  -48.281  1.00 36.78  ? 168 THR B N     1 
ATOM   5368  C  CA    . THR B 1 168 ? -15.932 25.924  -49.651  1.00 35.86  ? 168 THR B CA    1 
ATOM   5369  C  C     . THR B 1 168 ? -16.878 24.820  -50.104  1.00 33.20  ? 168 THR B C     1 
ATOM   5370  O  O     . THR B 1 168 ? -17.138 23.892  -49.344  1.00 35.90  ? 168 THR B O     1 
ATOM   5371  C  CB    . THR B 1 168 ? -14.706 26.064  -50.574  1.00 35.48  ? 168 THR B CB    1 
ATOM   5372  O  OG1   . THR B 1 168 ? -14.345 24.749  -50.999  1.00 40.24  ? 168 THR B OG1   1 
ATOM   5373  C  CG2   . THR B 1 168 ? -13.545 26.778  -49.911  1.00 38.26  ? 168 THR B CG2   1 
ATOM   5374  N  N     . PRO B 1 169 ? -17.397 24.871  -51.345  1.00 33.77  ? 169 PRO B N     1 
ATOM   5375  C  CA    . PRO B 1 169 ? -18.175 23.773  -51.898  1.00 36.96  ? 169 PRO B CA    1 
ATOM   5376  C  C     . PRO B 1 169 ? -17.436 22.442  -51.876  1.00 38.34  ? 169 PRO B C     1 
ATOM   5377  O  O     . PRO B 1 169 ? -18.089 21.421  -51.814  1.00 35.15  ? 169 PRO B O     1 
ATOM   5378  C  CB    . PRO B 1 169 ? -18.534 24.243  -53.330  1.00 36.45  ? 169 PRO B CB    1 
ATOM   5379  C  CG    . PRO B 1 169 ? -18.527 25.762  -53.209  1.00 36.73  ? 169 PRO B CG    1 
ATOM   5380  C  CD    . PRO B 1 169 ? -17.390 26.032  -52.245  1.00 35.48  ? 169 PRO B CD    1 
ATOM   5381  N  N     . TYR B 1 170 ? -16.095 22.446  -51.873  1.00 39.25  ? 170 TYR B N     1 
ATOM   5382  C  CA    . TYR B 1 170 ? -15.334 21.210  -51.761  1.00 34.02  ? 170 TYR B CA    1 
ATOM   5383  C  C     . TYR B 1 170 ? -15.027 20.855  -50.300  1.00 36.65  ? 170 TYR B C     1 
ATOM   5384  O  O     . TYR B 1 170 ? -13.977 20.292  -49.965  1.00 37.79  ? 170 TYR B O     1 
ATOM   5385  C  CB    . TYR B 1 170 ? -14.061 21.315  -52.600  1.00 35.74  ? 170 TYR B CB    1 
ATOM   5386  C  CG    . TYR B 1 170 ? -14.241 21.143  -54.088  1.00 33.41  ? 170 TYR B CG    1 
ATOM   5387  C  CD1   . TYR B 1 170 ? -15.290 21.716  -54.796  1.00 37.50  ? 170 TYR B CD1   1 
ATOM   5388  C  CD2   . TYR B 1 170 ? -13.318 20.405  -54.804  1.00 36.95  ? 170 TYR B CD2   1 
ATOM   5389  C  CE1   . TYR B 1 170 ? -15.436 21.529  -56.167  1.00 34.87  ? 170 TYR B CE1   1 
ATOM   5390  C  CE2   . TYR B 1 170 ? -13.429 20.230  -56.172  1.00 37.51  ? 170 TYR B CE2   1 
ATOM   5391  C  CZ    . TYR B 1 170 ? -14.492 20.792  -56.863  1.00 37.96  ? 170 TYR B CZ    1 
ATOM   5392  O  OH    . TYR B 1 170 ? -14.550 20.566  -58.224  1.00 38.79  ? 170 TYR B OH    1 
ATOM   5393  N  N     . GLY B 1 171 ? -16.001 21.105  -49.425  1.00 35.11  ? 171 GLY B N     1 
ATOM   5394  C  CA    . GLY B 1 171 ? -15.759 21.119  -47.999  1.00 35.82  ? 171 GLY B CA    1 
ATOM   5395  C  C     . GLY B 1 171 ? -15.613 19.731  -47.385  1.00 33.27  ? 171 GLY B C     1 
ATOM   5396  O  O     . GLY B 1 171 ? -15.101 19.609  -46.294  1.00 35.73  ? 171 GLY B O     1 
ATOM   5397  N  N     . ASP B 1 172 ? -16.103 18.686  -48.033  1.00 35.26  ? 172 ASP B N     1 
ATOM   5398  C  CA    . ASP B 1 172 ? -15.953 17.346  -47.468  1.00 36.32  ? 172 ASP B CA    1 
ATOM   5399  C  C     . ASP B 1 172 ? -14.706 16.733  -48.089  1.00 35.11  ? 172 ASP B C     1 
ATOM   5400  O  O     . ASP B 1 172 ? -14.744 16.213  -49.199  1.00 35.66  ? 172 ASP B O     1 
ATOM   5401  C  CB    . ASP B 1 172 ? -17.229 16.534  -47.709  1.00 40.46  ? 172 ASP B CB    1 
ATOM   5402  C  CG    . ASP B 1 172 ? -17.183 15.086  -47.239  1.00 41.99  ? 172 ASP B CG    1 
ATOM   5403  O  OD1   . ASP B 1 172 ? -16.087 14.586  -46.855  1.00 36.45  ? 172 ASP B OD1   1 
ATOM   5404  O  OD2   . ASP B 1 172 ? -18.255 14.476  -47.260  1.00 39.48  ? 172 ASP B OD2   1 
ATOM   5405  N  N     . HIS B 1 173 ? -13.595 16.787  -47.355  1.00 34.94  ? 173 HIS B N     1 
ATOM   5406  C  CA    . HIS B 1 173 ? -12.285 16.546  -47.933  1.00 33.24  ? 173 HIS B CA    1 
ATOM   5407  C  C     . HIS B 1 173 ? -12.186 15.115  -48.445  1.00 34.52  ? 173 HIS B C     1 
ATOM   5408  O  O     . HIS B 1 173 ? -11.670 14.904  -49.532  1.00 35.55  ? 173 HIS B O     1 
ATOM   5409  C  CB    . HIS B 1 173 ? -11.206 16.888  -46.903  1.00 34.17  ? 173 HIS B CB    1 
ATOM   5410  C  CG    . HIS B 1 173 ? -11.149 18.344  -46.593  1.00 35.28  ? 173 HIS B CG    1 
ATOM   5411  N  ND1   . HIS B 1 173 ? -10.419 18.864  -45.556  1.00 41.65  ? 173 HIS B ND1   1 
ATOM   5412  C  CD2   . HIS B 1 173 ? -11.774 19.390  -47.170  1.00 41.81  ? 173 HIS B CD2   1 
ATOM   5413  C  CE1   . HIS B 1 173 ? -10.546 20.187  -45.558  1.00 45.04  ? 173 HIS B CE1   1 
ATOM   5414  N  NE2   . HIS B 1 173 ? -11.381 20.529  -46.532  1.00 40.85  ? 173 HIS B NE2   1 
ATOM   5415  N  N     . PHE B 1 174 ? -12.636 14.121  -47.667  1.00 33.27  ? 174 PHE B N     1 
ATOM   5416  C  CA    . PHE B 1 174 ? -12.482 12.756  -48.130  1.00 34.53  ? 174 PHE B CA    1 
ATOM   5417  C  C     . PHE B 1 174 ? -13.397 12.476  -49.327  1.00 34.79  ? 174 PHE B C     1 
ATOM   5418  O  O     . PHE B 1 174 ? -13.046 11.676  -50.197  1.00 37.36  ? 174 PHE B O     1 
ATOM   5419  C  CB    . PHE B 1 174 ? -12.696 11.725  -47.025  1.00 36.51  ? 174 PHE B CB    1 
ATOM   5420  C  CG    . PHE B 1 174 ? -12.191 10.367  -47.433  1.00 37.49  ? 174 PHE B CG    1 
ATOM   5421  C  CD1   . PHE B 1 174 ? -10.843 10.170  -47.691  1.00 38.04  ? 174 PHE B CD1   1 
ATOM   5422  C  CD2   . PHE B 1 174 ? -13.056 9.316   -47.647  1.00 37.94  ? 174 PHE B CD2   1 
ATOM   5423  C  CE1   . PHE B 1 174 ? -10.373 8.946   -48.127  1.00 38.01  ? 174 PHE B CE1   1 
ATOM   5424  C  CE2   . PHE B 1 174 ? -12.579 8.082   -48.052  1.00 39.93  ? 174 PHE B CE2   1 
ATOM   5425  C  CZ    . PHE B 1 174 ? -11.236 7.895   -48.289  1.00 41.36  ? 174 PHE B CZ    1 
ATOM   5426  N  N     . ALA B 1 175 ? -14.536 13.172  -49.432  1.00 33.69  ? 175 ALA B N     1 
ATOM   5427  C  CA    . ALA B 1 175 ? -15.401 12.967  -50.583  1.00 34.50  ? 175 ALA B CA    1 
ATOM   5428  C  C     . ALA B 1 175 ? -14.714 13.442  -51.876  1.00 35.62  ? 175 ALA B C     1 
ATOM   5429  O  O     . ALA B 1 175 ? -14.968 12.892  -52.928  1.00 36.14  ? 175 ALA B O     1 
ATOM   5430  C  CB    . ALA B 1 175 ? -16.747 13.621  -50.353  1.00 33.06  ? 175 ALA B CB    1 
ATOM   5431  N  N     . MET B 1 176 ? -13.773 14.392  -51.796  1.00 33.95  ? 176 MET B N     1 
ATOM   5432  C  CA    . MET B 1 176 ? -13.057 14.905  -52.956  1.00 35.53  ? 176 MET B CA    1 
ATOM   5433  C  C     . MET B 1 176 ? -11.823 14.063  -53.270  1.00 35.63  ? 176 MET B C     1 
ATOM   5434  O  O     . MET B 1 176 ? -11.107 14.328  -54.232  1.00 36.50  ? 176 MET B O     1 
ATOM   5435  C  CB    . MET B 1 176 ? -12.605 16.349  -52.705  1.00 34.71  ? 176 MET B CB    1 
ATOM   5436  C  CG    . MET B 1 176 ? -13.764 17.267  -52.436  1.00 38.50  ? 176 MET B CG    1 
ATOM   5437  S  SD    . MET B 1 176 ? -15.032 17.282  -53.763  1.00 42.92  ? 176 MET B SD    1 
ATOM   5438  C  CE    . MET B 1 176 ? -16.322 16.236  -53.106  1.00 48.82  ? 176 MET B CE    1 
ATOM   5439  N  N     . GLN B 1 177 ? -11.564 13.046  -52.455  1.00 38.46  ? 177 GLN B N     1 
ATOM   5440  C  CA    . GLN B 1 177 ? -10.405 12.208  -52.670  1.00 35.96  ? 177 GLN B CA    1 
ATOM   5441  C  C     . GLN B 1 177 ? -10.629 11.336  -53.908  1.00 41.46  ? 177 GLN B C     1 
ATOM   5442  O  O     . GLN B 1 177 ? -11.754 10.974  -54.244  1.00 37.27  ? 177 GLN B O     1 
ATOM   5443  C  CB    . GLN B 1 177 ? -10.138 11.418  -51.397  1.00 36.13  ? 177 GLN B CB    1 
ATOM   5444  C  CG    . GLN B 1 177 ? -9.000  10.415  -51.535  1.00 38.75  ? 177 GLN B CG    1 
ATOM   5445  C  CD    . GLN B 1 177 ? -9.452  9.046   -51.976  1.00 40.91  ? 177 GLN B CD    1 
ATOM   5446  O  OE1   . GLN B 1 177 ? -10.578 8.626   -51.732  1.00 41.78  ? 177 GLN B OE1   1 
ATOM   5447  N  NE2   . GLN B 1 177 ? -8.552  8.312   -52.599  1.00 39.07  ? 177 GLN B NE2   1 
ATOM   5448  N  N     . CYS B 1 178 ? -9.538  11.037  -54.623  1.00 39.87  ? 178 CYS B N     1 
ATOM   5449  C  CA    . CYS B 1 178 ? -9.608  10.229  -55.827  1.00 37.34  ? 178 CYS B CA    1 
ATOM   5450  C  C     . CYS B 1 178 ? -8.228  9.634   -56.083  1.00 40.16  ? 178 CYS B C     1 
ATOM   5451  O  O     . CYS B 1 178 ? -7.308  10.337  -56.513  1.00 35.75  ? 178 CYS B O     1 
ATOM   5452  C  CB    . CYS B 1 178 ? -10.034 11.082  -57.019  1.00 40.20  ? 178 CYS B CB    1 
ATOM   5453  S  SG    . CYS B 1 178 ? -10.463 10.099  -58.474  1.00 39.00  ? 178 CYS B SG    1 
ATOM   5454  N  N     . GLY B 1 179 ? -8.114  8.340   -55.792  1.00 34.51  ? 179 GLY B N     1 
ATOM   5455  C  CA    . GLY B 1 179 ? -6.901  7.582   -55.968  1.00 34.03  ? 179 GLY B CA    1 
ATOM   5456  C  C     . GLY B 1 179 ? -5.997  7.739   -54.756  1.00 37.99  ? 179 GLY B C     1 
ATOM   5457  O  O     . GLY B 1 179 ? -5.851  8.839   -54.193  1.00 38.81  ? 179 GLY B O     1 
ATOM   5458  N  N     . MET B 1 180 ? -5.437  6.611   -54.334  1.00 38.30  ? 180 MET B N     1 
ATOM   5459  C  CA    . MET B 1 180 ? -4.416  6.640   -53.320  1.00 36.32  ? 180 MET B CA    1 
ATOM   5460  C  C     . MET B 1 180 ? -3.461  5.477   -53.512  1.00 36.87  ? 180 MET B C     1 
ATOM   5461  O  O     . MET B 1 180 ? -3.785  4.479   -54.155  1.00 36.16  ? 180 MET B O     1 
ATOM   5462  C  CB    . MET B 1 180 ? -4.984  6.605   -51.901  1.00 40.14  ? 180 MET B CB    1 
ATOM   5463  C  CG    . MET B 1 180 ? -5.854  5.421   -51.583  1.00 41.00  ? 180 MET B CG    1 
ATOM   5464  S  SD    . MET B 1 180 ? -6.196  5.321   -49.785  1.00 43.68  ? 180 MET B SD    1 
ATOM   5465  C  CE    . MET B 1 180 ? -7.314  6.705   -49.561  1.00 42.58  ? 180 MET B CE    1 
ATOM   5466  N  N     . GLU B 1 181 ? -2.284  5.677   -52.912  1.00 39.70  ? 181 GLU B N     1 
ATOM   5467  C  CA    . GLU B 1 181 ? -1.280  4.653   -52.762  1.00 42.55  ? 181 GLU B CA    1 
ATOM   5468  C  C     . GLU B 1 181 ? -1.137  4.377   -51.272  1.00 37.52  ? 181 GLU B C     1 
ATOM   5469  O  O     . GLU B 1 181 ? -1.004  5.302   -50.474  1.00 35.70  ? 181 GLU B O     1 
ATOM   5470  C  CB    . GLU B 1 181 ? 0.059   5.113   -53.342  1.00 41.39  ? 181 GLU B CB    1 
ATOM   5471  C  CG    . GLU B 1 181 ? 1.121   4.042   -53.273  1.00 44.90  ? 181 GLU B CG    1 
ATOM   5472  C  CD    . GLU B 1 181 ? 2.424   4.533   -53.868  1.00 45.95  ? 181 GLU B CD    1 
ATOM   5473  O  OE1   . GLU B 1 181 ? 2.608   4.317   -55.072  1.00 42.47  ? 181 GLU B OE1   1 
ATOM   5474  O  OE2   . GLU B 1 181 ? 3.192   5.201   -53.132  1.00 43.45  ? 181 GLU B OE2   1 
ATOM   5475  N  N     . VAL B 1 182 ? -1.106  3.088   -50.935  1.00 34.87  ? 182 VAL B N     1 
ATOM   5476  C  CA    . VAL B 1 182 ? -1.092  2.649   -49.555  1.00 38.62  ? 182 VAL B CA    1 
ATOM   5477  C  C     . VAL B 1 182 ? -0.000  1.611   -49.431  1.00 40.70  ? 182 VAL B C     1 
ATOM   5478  O  O     . VAL B 1 182 ? 0.055   0.698   -50.245  1.00 41.25  ? 182 VAL B O     1 
ATOM   5479  C  CB    . VAL B 1 182 ? -2.440  2.025   -49.125  1.00 40.32  ? 182 VAL B CB    1 
ATOM   5480  C  CG1   . VAL B 1 182 ? -2.497  1.801   -47.633  1.00 46.63  ? 182 VAL B CG1   1 
ATOM   5481  C  CG2   . VAL B 1 182 ? -3.626  2.873   -49.553  1.00 43.32  ? 182 VAL B CG2   1 
ATOM   5482  N  N     . VAL B 1 183 ? 0.808   1.757   -48.381  1.00 40.88  ? 183 VAL B N     1 
ATOM   5483  C  CA    . VAL B 1 183 ? 1.637   0.683   -47.883  1.00 42.04  ? 183 VAL B CA    1 
ATOM   5484  C  C     . VAL B 1 183 ? 0.830   -0.125  -46.876  1.00 41.87  ? 183 VAL B C     1 
ATOM   5485  O  O     . VAL B 1 183 ? 0.458   0.373   -45.822  1.00 42.73  ? 183 VAL B O     1 
ATOM   5486  C  CB    . VAL B 1 183 ? 2.929   1.246   -47.261  1.00 42.25  ? 183 VAL B CB    1 
ATOM   5487  C  CG1   . VAL B 1 183 ? 3.726   0.165   -46.551  1.00 46.79  ? 183 VAL B CG1   1 
ATOM   5488  C  CG2   . VAL B 1 183 ? 3.762   1.920   -48.326  1.00 45.16  ? 183 VAL B CG2   1 
ATOM   5489  N  N     . LEU B 1 184 ? 0.570   -1.387  -47.227  1.00 44.46  ? 184 LEU B N     1 
ATOM   5490  C  CA    . LEU B 1 184 ? -0.139  -2.304  -46.359  1.00 44.03  ? 184 LEU B CA    1 
ATOM   5491  C  C     . LEU B 1 184 ? 0.734   -2.672  -45.167  1.00 47.03  ? 184 LEU B C     1 
ATOM   5492  O  O     . LEU B 1 184 ? 1.940   -2.440  -45.146  1.00 45.31  ? 184 LEU B O     1 
ATOM   5493  C  CB    . LEU B 1 184 ? -0.530  -3.543  -47.164  1.00 47.64  ? 184 LEU B CB    1 
ATOM   5494  C  CG    . LEU B 1 184 ? -1.481  -3.279  -48.328  1.00 47.15  ? 184 LEU B CG    1 
ATOM   5495  C  CD1   . LEU B 1 184 ? -1.953  -4.596  -48.949  1.00 52.60  ? 184 LEU B CD1   1 
ATOM   5496  C  CD2   . LEU B 1 184 ? -2.653  -2.437  -47.864  1.00 50.38  ? 184 LEU B CD2   1 
ATOM   5497  N  N     . PRO B 1 185 ? 0.133   -3.240  -44.108  1.00 43.29  ? 185 PRO B N     1 
ATOM   5498  C  CA    . PRO B 1 185 ? 0.879   -3.569  -42.911  1.00 44.49  ? 185 PRO B CA    1 
ATOM   5499  C  C     . PRO B 1 185 ? 1.918   -4.658  -43.131  1.00 48.29  ? 185 PRO B C     1 
ATOM   5500  O  O     . PRO B 1 185 ? 2.653   -4.971  -42.207  1.00 49.24  ? 185 PRO B O     1 
ATOM   5501  C  CB    . PRO B 1 185 ? -0.180  -4.082  -41.937  1.00 42.29  ? 185 PRO B CB    1 
ATOM   5502  C  CG    . PRO B 1 185 ? -1.472  -3.557  -42.497  1.00 45.04  ? 185 PRO B CG    1 
ATOM   5503  C  CD    . PRO B 1 185 ? -1.285  -3.570  -43.994  1.00 43.75  ? 185 PRO B CD    1 
ATOM   5504  N  N     . ASN B 1 186 ? 1.953   -5.264  -44.323  1.00 49.74  ? 186 ASN B N     1 
ATOM   5505  C  CA    . ASN B 1 186 ? 2.972   -6.269  -44.588  1.00 52.76  ? 186 ASN B CA    1 
ATOM   5506  C  C     . ASN B 1 186 ? 4.145   -5.627  -45.316  1.00 54.78  ? 186 ASN B C     1 
ATOM   5507  O  O     . ASN B 1 186 ? 5.126   -6.305  -45.577  1.00 57.43  ? 186 ASN B O     1 
ATOM   5508  C  CB    . ASN B 1 186 ? 2.446   -7.475  -45.368  1.00 44.52  ? 186 ASN B CB    1 
ATOM   5509  C  CG    . ASN B 1 186 ? 1.901   -7.074  -46.714  1.00 44.98  ? 186 ASN B CG    1 
ATOM   5510  O  OD1   . ASN B 1 186 ? 1.848   -5.886  -47.023  1.00 48.91  ? 186 ASN B OD1   1 
ATOM   5511  N  ND2   . ASN B 1 186 ? 1.487   -8.046  -47.508  1.00 48.79  ? 186 ASN B ND2   1 
ATOM   5512  N  N     . GLY B 1 187 ? 4.035   -4.330  -45.632  1.00 53.36  ? 187 GLY B N     1 
ATOM   5513  C  CA    . GLY B 1 187 ? 5.101   -3.598  -46.302  1.00 49.11  ? 187 GLY B CA    1 
ATOM   5514  C  C     . GLY B 1 187 ? 4.977   -3.579  -47.828  1.00 47.24  ? 187 GLY B C     1 
ATOM   5515  O  O     . GLY B 1 187 ? 5.816   -2.988  -48.499  1.00 48.18  ? 187 GLY B O     1 
ATOM   5516  N  N     . GLU B 1 188 ? 3.929   -4.204  -48.381  1.00 49.49  ? 188 GLU B N     1 
ATOM   5517  C  CA    . GLU B 1 188 ? 3.653   -4.156  -49.812  1.00 52.13  ? 188 GLU B CA    1 
ATOM   5518  C  C     . GLU B 1 188 ? 2.820   -2.915  -50.139  1.00 52.06  ? 188 GLU B C     1 
ATOM   5519  O  O     . GLU B 1 188 ? 2.099   -2.407  -49.276  1.00 50.14  ? 188 GLU B O     1 
ATOM   5520  C  CB    . GLU B 1 188 ? 2.906   -5.418  -50.257  1.00 58.35  ? 188 GLU B CB    1 
ATOM   5521  C  CG    . GLU B 1 188 ? 3.682   -6.710  -50.028  1.00 66.12  ? 188 GLU B CG    1 
ATOM   5522  C  CD    . GLU B 1 188 ? 4.942   -6.830  -50.869  1.00 72.35  ? 188 GLU B CD    1 
ATOM   5523  O  OE1   . GLU B 1 188 ? 4.807   -6.957  -52.102  1.00 77.59  ? 188 GLU B OE1   1 
ATOM   5524  O  OE2   . GLU B 1 188 ? 6.056   -6.766  -50.296  1.00 68.79  ? 188 GLU B OE2   1 
ATOM   5525  N  N     . VAL B 1 189 ? 2.889   -2.463  -51.405  1.00 45.04  ? 189 VAL B N     1 
ATOM   5526  C  CA    . VAL B 1 189 ? 2.251   -1.220  -51.812  1.00 44.90  ? 189 VAL B CA    1 
ATOM   5527  C  C     . VAL B 1 189 ? 1.153   -1.514  -52.842  1.00 44.19  ? 189 VAL B C     1 
ATOM   5528  O  O     . VAL B 1 189 ? 1.313   -2.362  -53.706  1.00 44.19  ? 189 VAL B O     1 
ATOM   5529  C  CB    . VAL B 1 189 ? 3.294   -0.195  -52.305  1.00 48.14  ? 189 VAL B CB    1 
ATOM   5530  C  CG1   . VAL B 1 189 ? 4.027   -0.619  -53.577  1.00 51.14  ? 189 VAL B CG1   1 
ATOM   5531  C  CG2   . VAL B 1 189 ? 2.666   1.165   -52.489  1.00 44.35  ? 189 VAL B CG2   1 
ATOM   5532  N  N     . VAL B 1 190 ? -0.005  -0.861  -52.688  1.00 45.10  ? 190 VAL B N     1 
ATOM   5533  C  CA    . VAL B 1 190 ? -1.133  -1.004  -53.596  1.00 42.56  ? 190 VAL B CA    1 
ATOM   5534  C  C     . VAL B 1 190 ? -1.552  0.393   -54.007  1.00 39.33  ? 190 VAL B C     1 
ATOM   5535  O  O     . VAL B 1 190 ? -1.443  1.322   -53.226  1.00 42.14  ? 190 VAL B O     1 
ATOM   5536  C  CB    . VAL B 1 190 ? -2.325  -1.740  -52.949  1.00 48.43  ? 190 VAL B CB    1 
ATOM   5537  C  CG1   . VAL B 1 190 ? -1.960  -3.150  -52.516  1.00 55.26  ? 190 VAL B CG1   1 
ATOM   5538  C  CG2   . VAL B 1 190 ? -2.880  -0.969  -51.765  1.00 49.23  ? 190 VAL B CG2   1 
ATOM   5539  N  N     . ARG B 1 191 ? -2.051  0.517   -55.224  1.00 39.62  ? 191 ARG B N     1 
ATOM   5540  C  CA    . ARG B 1 191 ? -2.737  1.710   -55.652  1.00 37.25  ? 191 ARG B CA    1 
ATOM   5541  C  C     . ARG B 1 191 ? -4.213  1.390   -55.902  1.00 40.76  ? 191 ARG B C     1 
ATOM   5542  O  O     . ARG B 1 191 ? -4.566  0.334   -56.431  1.00 40.32  ? 191 ARG B O     1 
ATOM   5543  C  CB    . ARG B 1 191 ? -2.052  2.261   -56.899  1.00 38.07  ? 191 ARG B CB    1 
ATOM   5544  C  CG    . ARG B 1 191 ? -0.660  2.815   -56.624  1.00 42.12  ? 191 ARG B CG    1 
ATOM   5545  C  CD    . ARG B 1 191 ? -0.034  3.484   -57.836  1.00 44.40  ? 191 ARG B CD    1 
ATOM   5546  N  NE    . ARG B 1 191 ? 1.251   4.088   -57.488  1.00 49.01  ? 191 ARG B NE    1 
ATOM   5547  C  CZ    . ARG B 1 191 ? 2.090   4.625   -58.366  1.00 52.08  ? 191 ARG B CZ    1 
ATOM   5548  N  NH1   . ARG B 1 191 ? 1.836   4.530   -59.654  1.00 52.75  ? 191 ARG B NH1   1 
ATOM   5549  N  NH2   . ARG B 1 191 ? 3.184   5.245   -57.963  1.00 55.19  ? 191 ARG B NH2   1 
ATOM   5550  N  N     . THR B 1 192 ? -5.084  2.325   -55.520  1.00 38.81  ? 192 THR B N     1 
ATOM   5551  C  CA    . THR B 1 192 ? -6.510  2.100   -55.664  1.00 39.01  ? 192 THR B CA    1 
ATOM   5552  C  C     . THR B 1 192 ? -7.001  2.671   -56.975  1.00 41.42  ? 192 THR B C     1 
ATOM   5553  O  O     . THR B 1 192 ? -6.289  3.444   -57.628  1.00 40.50  ? 192 THR B O     1 
ATOM   5554  C  CB    . THR B 1 192 ? -7.322  2.746   -54.539  1.00 39.24  ? 192 THR B CB    1 
ATOM   5555  O  OG1   . THR B 1 192 ? -7.157  4.169   -54.626  1.00 40.23  ? 192 THR B OG1   1 
ATOM   5556  C  CG2   . THR B 1 192 ? -6.913  2.190   -53.196  1.00 39.74  ? 192 THR B CG2   1 
ATOM   5557  N  N     . GLY B 1 193 ? -8.240  2.274   -57.312  1.00 43.10  ? 193 GLY B N     1 
ATOM   5558  C  CA    . GLY B 1 193 ? -8.944  2.844   -58.443  1.00 41.67  ? 193 GLY B CA    1 
ATOM   5559  C  C     . GLY B 1 193 ? -8.181  2.585   -59.736  1.00 38.43  ? 193 GLY B C     1 
ATOM   5560  O  O     . GLY B 1 193 ? -7.653  1.491   -59.938  1.00 34.42  ? 193 GLY B O     1 
ATOM   5561  N  N     . MET B 1 194 ? -8.058  3.632   -60.557  1.00 37.34  ? 194 MET B N     1 
ATOM   5562  C  CA    . MET B 1 194 ? -7.481  3.493   -61.879  1.00 38.58  ? 194 MET B CA    1 
ATOM   5563  C  C     . MET B 1 194 ? -5.954  3.414   -61.755  1.00 40.23  ? 194 MET B C     1 
ATOM   5564  O  O     . MET B 1 194 ? -5.273  3.127   -62.733  1.00 36.80  ? 194 MET B O     1 
ATOM   5565  C  CB    . MET B 1 194 ? -7.897  4.664   -62.775  1.00 41.40  ? 194 MET B CB    1 
ATOM   5566  C  CG    . MET B 1 194 ? -9.382  4.702   -63.099  1.00 40.76  ? 194 MET B CG    1 
ATOM   5567  S  SD    . MET B 1 194 ? -10.026 3.162   -63.757  1.00 42.93  ? 194 MET B SD    1 
ATOM   5568  C  CE    . MET B 1 194 ? -8.983  2.854   -65.181  1.00 43.49  ? 194 MET B CE    1 
ATOM   5569  N  N     . GLY B 1 195 ? -5.427  3.624   -60.542  1.00 40.88  ? 195 GLY B N     1 
ATOM   5570  C  CA    . GLY B 1 195 ? -4.002  3.523   -60.283  1.00 44.42  ? 195 GLY B CA    1 
ATOM   5571  C  C     . GLY B 1 195 ? -3.518  2.074   -60.307  1.00 45.92  ? 195 GLY B C     1 
ATOM   5572  O  O     . GLY B 1 195 ? -2.326  1.821   -60.421  1.00 45.78  ? 195 GLY B O     1 
ATOM   5573  N  N     . ALA B 1 196 ? -4.441  1.116   -60.202  1.00 42.34  ? 196 ALA B N     1 
ATOM   5574  C  CA    . ALA B 1 196 ? -4.086  -0.284  -60.359  1.00 41.15  ? 196 ALA B CA    1 
ATOM   5575  C  C     . ALA B 1 196 ? -3.929  -0.650  -61.840  1.00 42.32  ? 196 ALA B C     1 
ATOM   5576  O  O     . ALA B 1 196 ? -3.554  -1.767  -62.142  1.00 43.54  ? 196 ALA B O     1 
ATOM   5577  C  CB    . ALA B 1 196 ? -5.130  -1.151  -59.690  1.00 40.27  ? 196 ALA B CB    1 
ATOM   5578  N  N     . MET B 1 197 ? -4.262  0.256   -62.762  1.00 43.00  ? 197 MET B N     1 
ATOM   5579  C  CA    . MET B 1 197 ? -4.112  0.023   -64.190  1.00 45.80  ? 197 MET B CA    1 
ATOM   5580  C  C     . MET B 1 197 ? -2.775  0.611   -64.638  1.00 43.63  ? 197 MET B C     1 
ATOM   5581  O  O     . MET B 1 197 ? -2.592  1.821   -64.594  1.00 43.81  ? 197 MET B O     1 
ATOM   5582  C  CB    . MET B 1 197 ? -5.284  0.667   -64.944  1.00 44.65  ? 197 MET B CB    1 
ATOM   5583  C  CG    . MET B 1 197 ? -5.126  0.916   -66.468  1.00 44.12  ? 197 MET B CG    1 
ATOM   5584  S  SD    . MET B 1 197 ? -4.921  -0.574  -67.493  1.00 52.67  ? 197 MET B SD    1 
ATOM   5585  C  CE    . MET B 1 197 ? -6.478  -1.431  -67.228  1.00 54.82  ? 197 MET B CE    1 
ATOM   5586  N  N     . PRO B 1 198 ? -1.779  -0.206  -65.049  1.00 45.81  ? 198 PRO B N     1 
ATOM   5587  C  CA    . PRO B 1 198 ? -0.524  0.337   -65.575  1.00 43.98  ? 198 PRO B CA    1 
ATOM   5588  C  C     . PRO B 1 198 ? -0.789  1.236   -66.767  1.00 44.08  ? 198 PRO B C     1 
ATOM   5589  O  O     . PRO B 1 198 ? -1.601  0.914   -67.630  1.00 42.65  ? 198 PRO B O     1 
ATOM   5590  C  CB    . PRO B 1 198 ? 0.267   -0.892  -66.026  1.00 47.94  ? 198 PRO B CB    1 
ATOM   5591  C  CG    . PRO B 1 198 ? -0.279  -1.999  -65.158  1.00 46.66  ? 198 PRO B CG    1 
ATOM   5592  C  CD    . PRO B 1 198 ? -1.764  -1.675  -65.009  1.00 41.24  ? 198 PRO B CD    1 
ATOM   5593  N  N     . GLY B 1 199 ? -0.121  2.387   -66.770  1.00 45.23  ? 199 GLY B N     1 
ATOM   5594  C  CA    . GLY B 1 199 ? -0.167  3.272   -67.911  1.00 44.65  ? 199 GLY B CA    1 
ATOM   5595  C  C     . GLY B 1 199 ? -1.472  4.063   -67.997  1.00 43.28  ? 199 GLY B C     1 
ATOM   5596  O  O     . GLY B 1 199 ? -1.763  4.677   -69.019  1.00 40.48  ? 199 GLY B O     1 
ATOM   5597  N  N     . ASN B 1 200 ? -2.231  4.115   -66.910  1.00 41.41  ? 200 ASN B N     1 
ATOM   5598  C  CA    . ASN B 1 200 ? -3.486  4.857   -66.918  1.00 42.34  ? 200 ASN B CA    1 
ATOM   5599  C  C     . ASN B 1 200 ? -3.207  6.361   -67.004  1.00 44.55  ? 200 ASN B C     1 
ATOM   5600  O  O     . ASN B 1 200 ? -2.132  6.833   -66.664  1.00 41.59  ? 200 ASN B O     1 
ATOM   5601  C  CB    . ASN B 1 200 ? -4.287  4.560   -65.647  1.00 39.13  ? 200 ASN B CB    1 
ATOM   5602  C  CG    . ASN B 1 200 ? -3.674  5.233   -64.431  1.00 43.07  ? 200 ASN B CG    1 
ATOM   5603  O  OD1   . ASN B 1 200 ? -3.973  6.391   -64.139  1.00 43.22  ? 200 ASN B OD1   1 
ATOM   5604  N  ND2   . ASN B 1 200 ? -2.838  4.511   -63.699  1.00 39.81  ? 200 ASN B ND2   1 
ATOM   5605  N  N     . ASN B 1 201 ? -4.228  7.132   -67.350  1.00 40.29  ? 201 ASN B N     1 
ATOM   5606  C  CA    . ASN B 1 201 ? -4.169  8.572   -67.210  1.00 43.92  ? 201 ASN B CA    1 
ATOM   5607  C  C     . ASN B 1 201 ? -5.428  9.042   -66.479  1.00 40.40  ? 201 ASN B C     1 
ATOM   5608  O  O     . ASN B 1 201 ? -5.959  10.096  -66.803  1.00 44.15  ? 201 ASN B O     1 
ATOM   5609  C  CB    . ASN B 1 201 ? -4.033  9.216   -68.592  1.00 43.05  ? 201 ASN B CB    1 
ATOM   5610  C  CG    . ASN B 1 201 ? -5.059  8.694   -69.588  1.00 51.52  ? 201 ASN B CG    1 
ATOM   5611  O  OD1   . ASN B 1 201 ? -5.952  7.909   -69.235  1.00 51.44  ? 201 ASN B OD1   1 
ATOM   5612  N  ND2   . ASN B 1 201 ? -4.923  9.109   -70.848  1.00 49.19  ? 201 ASN B ND2   1 
ATOM   5613  N  N     . THR B 1 202 ? -5.923  8.220   -65.541  1.00 42.76  ? 202 THR B N     1 
ATOM   5614  C  CA    . THR B 1 202 ? -7.255  8.392   -64.980  1.00 35.86  ? 202 THR B CA    1 
ATOM   5615  C  C     . THR B 1 202 ? -7.259  8.214   -63.462  1.00 38.58  ? 202 THR B C     1 
ATOM   5616  O  O     . THR B 1 202 ? -8.324  8.270   -62.846  1.00 38.41  ? 202 THR B O     1 
ATOM   5617  C  CB    . THR B 1 202 ? -8.259  7.468   -65.684  1.00 36.53  ? 202 THR B CB    1 
ATOM   5618  O  OG1   . THR B 1 202 ? -7.794  6.118   -65.761  1.00 38.45  ? 202 THR B OG1   1 
ATOM   5619  C  CG2   . THR B 1 202 ? -8.578  7.946   -67.074  1.00 38.78  ? 202 THR B CG2   1 
ATOM   5620  N  N     . TRP B 1 203 ? -6.078  8.072   -62.840  1.00 38.09  ? 203 TRP B N     1 
ATOM   5621  C  CA    . TRP B 1 203 ? -5.981  7.866   -61.396  1.00 38.24  ? 203 TRP B CA    1 
ATOM   5622  C  C     . TRP B 1 203 ? -6.714  8.960   -60.608  1.00 38.95  ? 203 TRP B C     1 
ATOM   5623  O  O     . TRP B 1 203 ? -7.357  8.698   -59.589  1.00 36.15  ? 203 TRP B O     1 
ATOM   5624  C  CB    . TRP B 1 203 ? -4.510  7.832   -60.956  1.00 40.36  ? 203 TRP B CB    1 
ATOM   5625  C  CG    . TRP B 1 203 ? -4.280  7.196   -59.620  1.00 40.80  ? 203 TRP B CG    1 
ATOM   5626  C  CD1   . TRP B 1 203 ? -5.181  6.485   -58.880  1.00 42.00  ? 203 TRP B CD1   1 
ATOM   5627  C  CD2   . TRP B 1 203 ? -3.049  7.185   -58.877  1.00 39.61  ? 203 TRP B CD2   1 
ATOM   5628  N  NE1   . TRP B 1 203 ? -4.586  6.011   -57.739  1.00 41.24  ? 203 TRP B NE1   1 
ATOM   5629  C  CE2   . TRP B 1 203 ? -3.284  6.451   -57.697  1.00 39.78  ? 203 TRP B CE2   1 
ATOM   5630  C  CE3   . TRP B 1 203 ? -1.767  7.697   -59.105  1.00 40.09  ? 203 TRP B CE3   1 
ATOM   5631  C  CZ2   . TRP B 1 203 ? -2.284  6.219   -56.754  1.00 36.69  ? 203 TRP B CZ2   1 
ATOM   5632  C  CZ3   . TRP B 1 203 ? -0.790  7.501   -58.153  1.00 42.10  ? 203 TRP B CZ3   1 
ATOM   5633  C  CH2   . TRP B 1 203 ? -1.046  6.767   -56.992  1.00 40.81  ? 203 TRP B CH2   1 
ATOM   5634  N  N     . GLN B 1 204 ? -6.565  10.213  -61.039  1.00 38.38  ? 204 GLN B N     1 
ATOM   5635  C  CA    . GLN B 1 204 ? -7.159  11.313  -60.300  1.00 37.04  ? 204 GLN B CA    1 
ATOM   5636  C  C     . GLN B 1 204 ? -8.469  11.762  -60.946  1.00 35.46  ? 204 GLN B C     1 
ATOM   5637  O  O     . GLN B 1 204 ? -9.015  12.808  -60.570  1.00 36.55  ? 204 GLN B O     1 
ATOM   5638  C  CB    . GLN B 1 204 ? -6.145  12.441  -60.160  1.00 34.39  ? 204 GLN B CB    1 
ATOM   5639  C  CG    . GLN B 1 204 ? -5.341  12.333  -58.877  1.00 37.12  ? 204 GLN B CG    1 
ATOM   5640  C  CD    . GLN B 1 204 ? -4.478  11.098  -58.831  1.00 38.83  ? 204 GLN B CD    1 
ATOM   5641  O  OE1   . GLN B 1 204 ? -3.482  11.002  -59.531  1.00 43.39  ? 204 GLN B OE1   1 
ATOM   5642  N  NE2   . GLN B 1 204 ? -4.837  10.134  -57.992  1.00 37.17  ? 204 GLN B NE2   1 
ATOM   5643  N  N     . LEU B 1 205 ? -9.002  10.956  -61.877  1.00 34.53  ? 205 LEU B N     1 
ATOM   5644  C  CA    . LEU B 1 205 ? -10.164 11.367  -62.656  1.00 34.08  ? 205 LEU B CA    1 
ATOM   5645  C  C     . LEU B 1 205 ? -11.402 10.526  -62.337  1.00 36.67  ? 205 LEU B C     1 
ATOM   5646  O  O     . LEU B 1 205 ? -12.508 11.010  -62.495  1.00 34.37  ? 205 LEU B O     1 
ATOM   5647  C  CB    . LEU B 1 205 ? -9.821  11.272  -64.146  1.00 38.47  ? 205 LEU B CB    1 
ATOM   5648  C  CG    . LEU B 1 205 ? -8.666  12.159  -64.625  1.00 41.43  ? 205 LEU B CG    1 
ATOM   5649  C  CD1   . LEU B 1 205 ? -8.562  12.141  -66.136  1.00 44.26  ? 205 LEU B CD1   1 
ATOM   5650  C  CD2   . LEU B 1 205 ? -8.829  13.601  -64.160  1.00 39.15  ? 205 LEU B CD2   1 
ATOM   5651  N  N     . PHE B 1 206 ? -11.225 9.249   -61.975  1.00 39.79  ? 206 PHE B N     1 
ATOM   5652  C  CA    . PHE B 1 206 ? -12.345 8.381   -61.680  1.00 39.04  ? 206 PHE B CA    1 
ATOM   5653  C  C     . PHE B 1 206 ? -12.024 7.575   -60.427  1.00 36.42  ? 206 PHE B C     1 
ATOM   5654  O  O     . PHE B 1 206 ? -11.001 6.900   -60.381  1.00 39.84  ? 206 PHE B O     1 
ATOM   5655  C  CB    . PHE B 1 206 ? -12.612 7.481   -62.889  1.00 40.73  ? 206 PHE B CB    1 
ATOM   5656  C  CG    . PHE B 1 206 ? -13.632 6.392   -62.671  1.00 34.82  ? 206 PHE B CG    1 
ATOM   5657  C  CD1   . PHE B 1 206 ? -14.956 6.710   -62.448  1.00 44.36  ? 206 PHE B CD1   1 
ATOM   5658  C  CD2   . PHE B 1 206 ? -13.275 5.058   -62.722  1.00 39.89  ? 206 PHE B CD2   1 
ATOM   5659  C  CE1   . PHE B 1 206 ? -15.897 5.717   -62.246  1.00 39.56  ? 206 PHE B CE1   1 
ATOM   5660  C  CE2   . PHE B 1 206 ? -14.215 4.062   -62.528  1.00 39.75  ? 206 PHE B CE2   1 
ATOM   5661  C  CZ    . PHE B 1 206 ? -15.529 4.397   -62.318  1.00 41.34  ? 206 PHE B CZ    1 
ATOM   5662  N  N     . LYS B 1 207 ? -12.924 7.605   -59.432  1.00 34.82  ? 207 LYS B N     1 
ATOM   5663  C  CA    . LYS B 1 207 ? -12.602 7.085   -58.108  1.00 35.51  ? 207 LYS B CA    1 
ATOM   5664  C  C     . LYS B 1 207 ? -12.523 5.568   -58.078  1.00 37.80  ? 207 LYS B C     1 
ATOM   5665  O  O     . LYS B 1 207 ? -11.719 5.006   -57.351  1.00 44.76  ? 207 LYS B O     1 
ATOM   5666  C  CB    . LYS B 1 207 ? -13.650 7.482   -57.075  1.00 36.34  ? 207 LYS B CB    1 
ATOM   5667  C  CG    . LYS B 1 207 ? -13.598 8.932   -56.616  1.00 41.44  ? 207 LYS B CG    1 
ATOM   5668  C  CD    . LYS B 1 207 ? -14.910 9.405   -55.988  1.00 40.41  ? 207 LYS B CD    1 
ATOM   5669  C  CE    . LYS B 1 207 ? -14.791 10.653  -55.130  1.00 36.36  ? 207 LYS B CE    1 
ATOM   5670  N  NZ    . LYS B 1 207 ? -14.291 10.318  -53.773  1.00 37.07  ? 207 LYS B NZ    1 
ATOM   5671  N  N     . TYR B 1 208 ? -13.430 4.891   -58.773  1.00 39.67  ? 208 TYR B N     1 
ATOM   5672  C  CA    . TYR B 1 208 ? -13.737 3.523   -58.382  1.00 41.91  ? 208 TYR B CA    1 
ATOM   5673  C  C     . TYR B 1 208 ? -12.708 2.550   -58.936  1.00 38.92  ? 208 TYR B C     1 
ATOM   5674  O  O     . TYR B 1 208 ? -12.297 1.612   -58.265  1.00 39.18  ? 208 TYR B O     1 
ATOM   5675  C  CB    . TYR B 1 208 ? -15.137 3.114   -58.849  1.00 37.47  ? 208 TYR B CB    1 
ATOM   5676  C  CG    . TYR B 1 208 ? -16.264 3.968   -58.324  1.00 42.64  ? 208 TYR B CG    1 
ATOM   5677  C  CD1   . TYR B 1 208 ? -16.343 4.324   -56.980  1.00 45.90  ? 208 TYR B CD1   1 
ATOM   5678  C  CD2   . TYR B 1 208 ? -17.304 4.359   -59.155  1.00 40.81  ? 208 TYR B CD2   1 
ATOM   5679  C  CE1   . TYR B 1 208 ? -17.392 5.093   -56.489  1.00 41.06  ? 208 TYR B CE1   1 
ATOM   5680  C  CE2   . TYR B 1 208 ? -18.361 5.116   -58.679  1.00 40.53  ? 208 TYR B CE2   1 
ATOM   5681  C  CZ    . TYR B 1 208 ? -18.404 5.489   -57.343  1.00 41.77  ? 208 TYR B CZ    1 
ATOM   5682  O  OH    . TYR B 1 208 ? -19.475 6.229   -56.888  1.00 44.48  ? 208 TYR B OH    1 
ATOM   5683  N  N     . GLY B 1 209 ? -12.299 2.797   -60.177  1.00 45.20  ? 209 GLY B N     1 
ATOM   5684  C  CA    . GLY B 1 209 ? -11.702 1.747   -60.967  1.00 42.31  ? 209 GLY B CA    1 
ATOM   5685  C  C     . GLY B 1 209 ? -12.696 0.609   -61.138  1.00 39.13  ? 209 GLY B C     1 
ATOM   5686  O  O     . GLY B 1 209 ? -13.826 0.823   -61.556  1.00 39.02  ? 209 GLY B O     1 
ATOM   5687  N  N     . TYR B 1 210 ? -12.251 -0.586  -60.782  1.00 39.65  ? 210 TYR B N     1 
ATOM   5688  C  CA    . TYR B 1 210 ? -13.032 -1.780  -60.968  1.00 41.20  ? 210 TYR B CA    1 
ATOM   5689  C  C     . TYR B 1 210 ? -12.933 -2.612  -59.702  1.00 41.26  ? 210 TYR B C     1 
ATOM   5690  O  O     . TYR B 1 210 ? -11.889 -2.670  -59.041  1.00 42.56  ? 210 TYR B O     1 
ATOM   5691  C  CB    . TYR B 1 210 ? -12.559 -2.579  -62.186  1.00 43.51  ? 210 TYR B CB    1 
ATOM   5692  C  CG    . TYR B 1 210 ? -13.242 -3.912  -62.401  1.00 42.93  ? 210 TYR B CG    1 
ATOM   5693  C  CD1   . TYR B 1 210 ? -14.596 -3.976  -62.702  1.00 41.32  ? 210 TYR B CD1   1 
ATOM   5694  C  CD2   . TYR B 1 210 ? -12.552 -5.110  -62.256  1.00 41.13  ? 210 TYR B CD2   1 
ATOM   5695  C  CE1   . TYR B 1 210 ? -15.230 -5.190  -62.887  1.00 42.85  ? 210 TYR B CE1   1 
ATOM   5696  C  CE2   . TYR B 1 210 ? -13.170 -6.333  -62.457  1.00 42.94  ? 210 TYR B CE2   1 
ATOM   5697  C  CZ    . TYR B 1 210 ? -14.516 -6.368  -62.770  1.00 45.45  ? 210 TYR B CZ    1 
ATOM   5698  O  OH    . TYR B 1 210 ? -15.182 -7.552  -62.968  1.00 50.87  ? 210 TYR B OH    1 
ATOM   5699  N  N     . GLY B 1 211 ? -14.067 -3.237  -59.385  1.00 36.14  ? 211 GLY B N     1 
ATOM   5700  C  CA    . GLY B 1 211 ? -14.171 -4.091  -58.222  1.00 39.05  ? 211 GLY B CA    1 
ATOM   5701  C  C     . GLY B 1 211 ? -14.431 -3.291  -56.957  1.00 36.23  ? 211 GLY B C     1 
ATOM   5702  O  O     . GLY B 1 211 ? -14.856 -2.140  -56.996  1.00 38.88  ? 211 GLY B O     1 
ATOM   5703  N  N     . PRO B 1 212 ? -14.215 -3.939  -55.802  1.00 37.38  ? 212 PRO B N     1 
ATOM   5704  C  CA    . PRO B 1 212 ? -14.507 -3.342  -54.496  1.00 38.57  ? 212 PRO B CA    1 
ATOM   5705  C  C     . PRO B 1 212 ? -13.874 -1.970  -54.296  1.00 38.81  ? 212 PRO B C     1 
ATOM   5706  O  O     . PRO B 1 212 ? -12.693 -1.782  -54.594  1.00 37.29  ? 212 PRO B O     1 
ATOM   5707  C  CB    . PRO B 1 212 ? -13.929 -4.356  -53.507  1.00 37.17  ? 212 PRO B CB    1 
ATOM   5708  C  CG    . PRO B 1 212 ? -13.991 -5.680  -54.259  1.00 41.90  ? 212 PRO B CG    1 
ATOM   5709  C  CD    . PRO B 1 212 ? -13.763 -5.334  -55.716  1.00 37.55  ? 212 PRO B CD    1 
ATOM   5710  N  N     . TYR B 1 213 ? -14.685 -1.028  -53.802  1.00 36.28  ? 213 TYR B N     1 
ATOM   5711  C  CA    . TYR B 1 213 ? -14.240 0.338   -53.603  1.00 34.14  ? 213 TYR B CA    1 
ATOM   5712  C  C     . TYR B 1 213 ? -13.681 0.431   -52.192  1.00 39.77  ? 213 TYR B C     1 
ATOM   5713  O  O     . TYR B 1 213 ? -14.439 0.389   -51.243  1.00 35.63  ? 213 TYR B O     1 
ATOM   5714  C  CB    . TYR B 1 213 ? -15.395 1.293   -53.896  1.00 34.99  ? 213 TYR B CB    1 
ATOM   5715  C  CG    . TYR B 1 213 ? -15.065 2.761   -53.817  1.00 37.54  ? 213 TYR B CG    1 
ATOM   5716  C  CD1   . TYR B 1 213 ? -13.819 3.253   -54.169  1.00 40.37  ? 213 TYR B CD1   1 
ATOM   5717  C  CD2   . TYR B 1 213 ? -16.019 3.673   -53.404  1.00 42.78  ? 213 TYR B CD2   1 
ATOM   5718  C  CE1   . TYR B 1 213 ? -13.533 4.611   -54.100  1.00 42.02  ? 213 TYR B CE1   1 
ATOM   5719  C  CE2   . TYR B 1 213 ? -15.753 5.034   -53.333  1.00 45.06  ? 213 TYR B CE2   1 
ATOM   5720  C  CZ    . TYR B 1 213 ? -14.505 5.507   -53.683  1.00 44.24  ? 213 TYR B CZ    1 
ATOM   5721  O  OH    . TYR B 1 213 ? -14.276 6.865   -53.599  1.00 51.92  ? 213 TYR B OH    1 
ATOM   5722  N  N     . VAL B 1 214 ? -12.350 0.533   -52.085  1.00 36.36  ? 214 VAL B N     1 
ATOM   5723  C  CA    . VAL B 1 214 ? -11.652 0.316   -50.836  1.00 40.06  ? 214 VAL B CA    1 
ATOM   5724  C  C     . VAL B 1 214 ? -10.918 1.562   -50.355  1.00 32.55  ? 214 VAL B C     1 
ATOM   5725  O  O     . VAL B 1 214 ? -10.359 1.508   -49.270  1.00 36.27  ? 214 VAL B O     1 
ATOM   5726  C  CB    . VAL B 1 214 ? -10.666 -0.861  -50.919  1.00 41.27  ? 214 VAL B CB    1 
ATOM   5727  C  CG1   . VAL B 1 214 ? -11.416 -2.155  -51.170  1.00 42.85  ? 214 VAL B CG1   1 
ATOM   5728  C  CG2   . VAL B 1 214 ? -9.581  -0.625  -51.963  1.00 40.24  ? 214 VAL B CG2   1 
ATOM   5729  N  N     . ASP B 1 215 ? -10.984 2.694   -51.059  1.00 34.50  ? 215 ASP B N     1 
ATOM   5730  C  CA    . ASP B 1 215 ? -10.282 3.889   -50.589  1.00 37.36  ? 215 ASP B CA    1 
ATOM   5731  C  C     . ASP B 1 215 ? -10.653 4.213   -49.140  1.00 41.31  ? 215 ASP B C     1 
ATOM   5732  O  O     . ASP B 1 215 ? -9.794  4.484   -48.307  1.00 37.78  ? 215 ASP B O     1 
ATOM   5733  C  CB    . ASP B 1 215 ? -10.505 5.075   -51.528  1.00 34.90  ? 215 ASP B CB    1 
ATOM   5734  C  CG    . ASP B 1 215 ? -9.856  4.828   -52.881  1.00 37.94  ? 215 ASP B CG    1 
ATOM   5735  O  OD1   . ASP B 1 215 ? -10.252 3.838   -53.549  1.00 40.20  ? 215 ASP B OD1   1 
ATOM   5736  O  OD2   . ASP B 1 215 ? -8.882  5.572   -53.218  1.00 36.25  ? 215 ASP B OD2   1 
ATOM   5737  N  N     . GLY B 1 216 ? -11.955 4.181   -48.855  1.00 35.76  ? 216 GLY B N     1 
ATOM   5738  C  CA    . GLY B 1 216 ? -12.490 4.499   -47.550  1.00 35.80  ? 216 GLY B CA    1 
ATOM   5739  C  C     . GLY B 1 216 ? -11.923 3.697   -46.388  1.00 37.26  ? 216 GLY B C     1 
ATOM   5740  O  O     . GLY B 1 216 ? -11.832 4.228   -45.279  1.00 31.49  ? 216 GLY B O     1 
ATOM   5741  N  N     . ILE B 1 217 ? -11.520 2.440   -46.602  1.00 37.61  ? 217 ILE B N     1 
ATOM   5742  C  CA    . ILE B 1 217 ? -11.112 1.635   -45.463  1.00 38.87  ? 217 ILE B CA    1 
ATOM   5743  C  C     . ILE B 1 217 ? -9.763  2.128   -44.922  1.00 39.66  ? 217 ILE B C     1 
ATOM   5744  O  O     . ILE B 1 217 ? -9.358  1.714   -43.828  1.00 39.00  ? 217 ILE B O     1 
ATOM   5745  C  CB    . ILE B 1 217 ? -11.059 0.128   -45.794  1.00 38.69  ? 217 ILE B CB    1 
ATOM   5746  C  CG1   . ILE B 1 217 ? -9.726  -0.272  -46.445  1.00 38.33  ? 217 ILE B CG1   1 
ATOM   5747  C  CG2   . ILE B 1 217 ? -12.266 -0.312  -46.613  1.00 40.32  ? 217 ILE B CG2   1 
ATOM   5748  C  CD1   . ILE B 1 217 ? -9.623  -1.768  -46.731  1.00 39.29  ? 217 ILE B CD1   1 
ATOM   5749  N  N     . PHE B 1 218 ? -9.039  2.974   -45.670  1.00 36.55  ? 218 PHE B N     1 
ATOM   5750  C  CA    . PHE B 1 218 ? -7.804  3.534   -45.125  1.00 37.82  ? 218 PHE B CA    1 
ATOM   5751  C  C     . PHE B 1 218 ? -8.038  4.903   -44.504  1.00 37.50  ? 218 PHE B C     1 
ATOM   5752  O  O     . PHE B 1 218 ? -7.080  5.594   -44.172  1.00 41.65  ? 218 PHE B O     1 
ATOM   5753  C  CB    . PHE B 1 218 ? -6.726  3.664   -46.202  1.00 35.69  ? 218 PHE B CB    1 
ATOM   5754  C  CG    . PHE B 1 218 ? -6.451  2.324   -46.793  1.00 36.40  ? 218 PHE B CG    1 
ATOM   5755  C  CD1   . PHE B 1 218 ? -5.812  1.361   -46.041  1.00 36.70  ? 218 PHE B CD1   1 
ATOM   5756  C  CD2   . PHE B 1 218 ? -7.009  1.968   -48.008  1.00 38.32  ? 218 PHE B CD2   1 
ATOM   5757  C  CE1   . PHE B 1 218 ? -5.649  0.081   -46.549  1.00 34.91  ? 218 PHE B CE1   1 
ATOM   5758  C  CE2   . PHE B 1 218 ? -6.857  0.687   -48.502  1.00 39.53  ? 218 PHE B CE2   1 
ATOM   5759  C  CZ    . PHE B 1 218 ? -6.161  -0.247  -47.774  1.00 38.84  ? 218 PHE B CZ    1 
ATOM   5760  N  N     . SER B 1 219 ? -9.300  5.322   -44.400  1.00 36.96  ? 219 SER B N     1 
ATOM   5761  C  CA    . SER B 1 219 ? -9.616  6.564   -43.701  1.00 36.68  ? 219 SER B CA    1 
ATOM   5762  C  C     . SER B 1 219 ? -10.076 6.215   -42.284  1.00 36.78  ? 219 SER B C     1 
ATOM   5763  O  O     . SER B 1 219 ? -10.601 5.121   -42.052  1.00 35.60  ? 219 SER B O     1 
ATOM   5764  C  CB    . SER B 1 219 ? -10.613 7.412   -44.494  1.00 39.28  ? 219 SER B CB    1 
ATOM   5765  O  OG    . SER B 1 219 ? -11.905 6.832   -44.526  1.00 36.17  ? 219 SER B OG    1 
ATOM   5766  N  N     . GLN B 1 220 ? -9.737  7.083   -41.315  1.00 38.50  ? 220 GLN B N     1 
ATOM   5767  C  CA    . GLN B 1 220 ? -9.962  6.849   -39.888  1.00 40.10  ? 220 GLN B CA    1 
ATOM   5768  C  C     . GLN B 1 220 ? -9.651  5.395   -39.498  1.00 40.84  ? 220 GLN B C     1 
ATOM   5769  O  O     . GLN B 1 220 ? -10.411 4.717   -38.802  1.00 43.17  ? 220 GLN B O     1 
ATOM   5770  C  CB    . GLN B 1 220 ? -11.391 7.236   -39.514  1.00 33.21  ? 220 GLN B CB    1 
ATOM   5771  C  CG    . GLN B 1 220 ? -11.610 8.741   -39.403  1.00 41.25  ? 220 GLN B CG    1 
ATOM   5772  C  CD    . GLN B 1 220 ? -12.914 9.063   -38.706  1.00 39.52  ? 220 GLN B CD    1 
ATOM   5773  O  OE1   . GLN B 1 220 ? -13.719 8.173   -38.462  1.00 40.12  ? 220 GLN B OE1   1 
ATOM   5774  N  NE2   . GLN B 1 220 ? -13.125 10.328  -38.374  1.00 38.58  ? 220 GLN B NE2   1 
ATOM   5775  N  N     . SER B 1 221 ? -8.470  4.950   -39.894  1.00 38.32  ? 221 SER B N     1 
ATOM   5776  C  CA    . SER B 1 221 ? -8.160  3.540   -39.937  1.00 37.97  ? 221 SER B CA    1 
ATOM   5777  C  C     . SER B 1 221 ? -6.695  3.291   -39.611  1.00 39.72  ? 221 SER B C     1 
ATOM   5778  O  O     . SER B 1 221 ? -5.877  4.188   -39.703  1.00 32.71  ? 221 SER B O     1 
ATOM   5779  C  CB    . SER B 1 221 ? -8.480  3.047   -41.305  1.00 41.06  ? 221 SER B CB    1 
ATOM   5780  O  OG    . SER B 1 221 ? -7.974  1.767   -41.522  1.00 43.74  ? 221 SER B OG    1 
ATOM   5781  N  N     . ASN B 1 222 ? -6.387  2.029   -39.315  1.00 38.60  ? 222 ASN B N     1 
ATOM   5782  C  CA    . ASN B 1 222 ? -5.029  1.564   -39.119  1.00 41.95  ? 222 ASN B CA    1 
ATOM   5783  C  C     . ASN B 1 222 ? -4.804  0.339   -39.987  1.00 43.54  ? 222 ASN B C     1 
ATOM   5784  O  O     . ASN B 1 222 ? -4.172  -0.622  -39.535  1.00 48.78  ? 222 ASN B O     1 
ATOM   5785  C  CB    . ASN B 1 222 ? -4.756  1.205   -37.650  1.00 42.48  ? 222 ASN B CB    1 
ATOM   5786  C  CG    . ASN B 1 222 ? -5.793  0.309   -36.996  1.00 41.89  ? 222 ASN B CG    1 
ATOM   5787  O  OD1   . ASN B 1 222 ? -6.723  -0.192  -37.628  1.00 42.59  ? 222 ASN B OD1   1 
ATOM   5788  N  ND2   . ASN B 1 222 ? -5.668  0.131   -35.693  1.00 45.94  ? 222 ASN B ND2   1 
ATOM   5789  N  N     . PHE B 1 223 ? -5.393  0.362   -41.194  1.00 41.29  ? 223 PHE B N     1 
ATOM   5790  C  CA    . PHE B 1 223 ? -5.314  -0.756  -42.118  1.00 38.05  ? 223 PHE B CA    1 
ATOM   5791  C  C     . PHE B 1 223 ? -4.151  -0.602  -43.112  1.00 39.61  ? 223 PHE B C     1 
ATOM   5792  O  O     . PHE B 1 223 ? -3.842  -1.542  -43.844  1.00 39.96  ? 223 PHE B O     1 
ATOM   5793  C  CB    . PHE B 1 223 ? -6.626  -0.906  -42.890  1.00 36.77  ? 223 PHE B CB    1 
ATOM   5794  C  CG    . PHE B 1 223 ? -7.848  -1.300  -42.103  1.00 35.12  ? 223 PHE B CG    1 
ATOM   5795  C  CD1   . PHE B 1 223 ? -7.762  -1.812  -40.820  1.00 39.43  ? 223 PHE B CD1   1 
ATOM   5796  C  CD2   . PHE B 1 223 ? -9.099  -1.179  -42.681  1.00 34.99  ? 223 PHE B CD2   1 
ATOM   5797  C  CE1   . PHE B 1 223 ? -8.894  -2.190  -40.121  1.00 38.77  ? 223 PHE B CE1   1 
ATOM   5798  C  CE2   . PHE B 1 223 ? -10.228 -1.572  -41.982  1.00 40.93  ? 223 PHE B CE2   1 
ATOM   5799  C  CZ    . PHE B 1 223 ? -10.127 -2.065  -40.704  1.00 37.28  ? 223 PHE B CZ    1 
ATOM   5800  N  N     . GLY B 1 224 ? -3.549  0.588   -43.169  1.00 38.51  ? 224 GLY B N     1 
ATOM   5801  C  CA    . GLY B 1 224 ? -2.439  0.873   -44.058  1.00 36.66  ? 224 GLY B CA    1 
ATOM   5802  C  C     . GLY B 1 224 ? -1.880  2.280   -43.852  1.00 39.54  ? 224 GLY B C     1 
ATOM   5803  O  O     . GLY B 1 224 ? -2.443  3.076   -43.094  1.00 37.88  ? 224 GLY B O     1 
ATOM   5804  N  N     . VAL B 1 225 ? -0.745  2.566   -44.512  1.00 39.27  ? 225 VAL B N     1 
ATOM   5805  C  CA    . VAL B 1 225 ? -0.112  3.874   -44.477  1.00 35.34  ? 225 VAL B CA    1 
ATOM   5806  C  C     . VAL B 1 225 ? -0.232  4.499   -45.860  1.00 38.66  ? 225 VAL B C     1 
ATOM   5807  O  O     . VAL B 1 225 ? 0.311   3.993   -46.842  1.00 38.77  ? 225 VAL B O     1 
ATOM   5808  C  CB    . VAL B 1 225 ? 1.363   3.741   -44.052  1.00 45.29  ? 225 VAL B CB    1 
ATOM   5809  C  CG1   . VAL B 1 225 ? 2.044   5.095   -43.932  1.00 42.66  ? 225 VAL B CG1   1 
ATOM   5810  C  CG2   . VAL B 1 225 ? 1.483   2.951   -42.759  1.00 46.84  ? 225 VAL B CG2   1 
ATOM   5811  N  N     . VAL B 1 226 ? -0.968  5.601   -45.943  1.00 39.03  ? 226 VAL B N     1 
ATOM   5812  C  CA    . VAL B 1 226 ? -1.180  6.242   -47.218  1.00 38.90  ? 226 VAL B CA    1 
ATOM   5813  C  C     . VAL B 1 226 ? 0.060   7.060   -47.520  1.00 39.27  ? 226 VAL B C     1 
ATOM   5814  O  O     . VAL B 1 226 ? 0.486   7.849   -46.672  1.00 43.64  ? 226 VAL B O     1 
ATOM   5815  C  CB    . VAL B 1 226 ? -2.440  7.119   -47.190  1.00 39.23  ? 226 VAL B CB    1 
ATOM   5816  C  CG1   . VAL B 1 226 ? -2.680  7.768   -48.537  1.00 38.42  ? 226 VAL B CG1   1 
ATOM   5817  C  CG2   . VAL B 1 226 ? -3.662  6.337   -46.714  1.00 41.44  ? 226 VAL B CG2   1 
ATOM   5818  N  N     . THR B 1 227 ? 0.597   6.893   -48.738  1.00 40.61  ? 227 THR B N     1 
ATOM   5819  C  CA    . THR B 1 227 ? 1.828   7.569   -49.118  1.00 40.27  ? 227 THR B CA    1 
ATOM   5820  C  C     . THR B 1 227 ? 1.589   8.507   -50.289  1.00 38.74  ? 227 THR B C     1 
ATOM   5821  O  O     . THR B 1 227 ? 2.439   9.332   -50.584  1.00 42.69  ? 227 THR B O     1 
ATOM   5822  C  CB    . THR B 1 227 ? 2.909   6.538   -49.421  1.00 41.35  ? 227 THR B CB    1 
ATOM   5823  O  OG1   . THR B 1 227 ? 2.372   5.614   -50.355  1.00 43.59  ? 227 THR B OG1   1 
ATOM   5824  C  CG2   . THR B 1 227 ? 3.345   5.771   -48.197  1.00 42.70  ? 227 THR B CG2   1 
ATOM   5825  N  N     . LYS B 1 228 ? 0.434   8.362   -50.952  1.00 42.58  ? 228 LYS B N     1 
ATOM   5826  C  CA    . LYS B 1 228 ? 0.011   9.261   -52.018  1.00 40.40  ? 228 LYS B CA    1 
ATOM   5827  C  C     . LYS B 1 228 ? -1.507  9.287   -52.032  1.00 38.99  ? 228 LYS B C     1 
ATOM   5828  O  O     . LYS B 1 228 ? -2.139  8.249   -51.879  1.00 39.91  ? 228 LYS B O     1 
ATOM   5829  C  CB    . LYS B 1 228 ? 0.463   8.820   -53.417  1.00 41.91  ? 228 LYS B CB    1 
ATOM   5830  C  CG    . LYS B 1 228 ? 1.969   8.684   -53.617  1.00 47.14  ? 228 LYS B CG    1 
ATOM   5831  C  CD    . LYS B 1 228 ? 2.358   8.278   -55.017  1.00 53.26  ? 228 LYS B CD    1 
ATOM   5832  C  CE    . LYS B 1 228 ? 3.860   8.137   -55.230  1.00 50.32  ? 228 LYS B CE    1 
ATOM   5833  N  NZ    . LYS B 1 228 ? 4.536   7.453   -54.101  1.00 50.54  ? 228 LYS B NZ    1 
ATOM   5834  N  N     . MET B 1 229 ? -2.052  10.471  -52.275  1.00 38.41  ? 229 MET B N     1 
ATOM   5835  C  CA    . MET B 1 229 ? -3.480  10.659  -52.342  1.00 38.99  ? 229 MET B CA    1 
ATOM   5836  C  C     . MET B 1 229 ? -3.760  11.756  -53.356  1.00 40.10  ? 229 MET B C     1 
ATOM   5837  O  O     . MET B 1 229 ? -3.074  12.775  -53.367  1.00 39.94  ? 229 MET B O     1 
ATOM   5838  C  CB    . MET B 1 229 ? -4.038  11.047  -50.973  1.00 37.08  ? 229 MET B CB    1 
ATOM   5839  C  CG    . MET B 1 229 ? -5.572  11.026  -50.918  1.00 42.20  ? 229 MET B CG    1 
ATOM   5840  S  SD    . MET B 1 229 ? -6.240  11.800  -49.427  1.00 42.53  ? 229 MET B SD    1 
ATOM   5841  C  CE    . MET B 1 229 ? -6.228  13.533  -49.877  1.00 42.10  ? 229 MET B CE    1 
ATOM   5842  N  N     . GLY B 1 230 ? -4.760  11.495  -54.212  1.00 41.86  ? 230 GLY B N     1 
ATOM   5843  C  CA    . GLY B 1 230 ? -5.304  12.492  -55.113  1.00 38.94  ? 230 GLY B CA    1 
ATOM   5844  C  C     . GLY B 1 230 ? -6.504  13.186  -54.493  1.00 38.25  ? 230 GLY B C     1 
ATOM   5845  O  O     . GLY B 1 230 ? -7.207  12.606  -53.662  1.00 33.69  ? 230 GLY B O     1 
ATOM   5846  N  N     . ILE B 1 231 ? -6.668  14.462  -54.849  1.00 37.31  ? 231 ILE B N     1 
ATOM   5847  C  CA    . ILE B 1 231 ? -7.784  15.228  -54.347  1.00 37.38  ? 231 ILE B CA    1 
ATOM   5848  C  C     . ILE B 1 231 ? -8.259  16.144  -55.454  1.00 37.28  ? 231 ILE B C     1 
ATOM   5849  O  O     . ILE B 1 231 ? -7.448  16.695  -56.195  1.00 36.06  ? 231 ILE B O     1 
ATOM   5850  C  CB    . ILE B 1 231 ? -7.437  15.977  -53.043  1.00 39.25  ? 231 ILE B CB    1 
ATOM   5851  C  CG1   . ILE B 1 231 ? -8.708  16.516  -52.378  1.00 39.14  ? 231 ILE B CG1   1 
ATOM   5852  C  CG2   . ILE B 1 231 ? -6.398  17.061  -53.268  1.00 39.64  ? 231 ILE B CG2   1 
ATOM   5853  C  CD1   . ILE B 1 231 ? -8.581  16.779  -50.893  1.00 37.04  ? 231 ILE B CD1   1 
ATOM   5854  N  N     . TRP B 1 232 ? -9.585  16.233  -55.597  1.00 33.56  ? 232 TRP B N     1 
ATOM   5855  C  CA    . TRP B 1 232 ? -10.138 17.155  -56.561  1.00 34.69  ? 232 TRP B CA    1 
ATOM   5856  C  C     . TRP B 1 232 ? -10.066 18.563  -55.976  1.00 34.07  ? 232 TRP B C     1 
ATOM   5857  O  O     . TRP B 1 232 ? -10.201 18.754  -54.765  1.00 35.04  ? 232 TRP B O     1 
ATOM   5858  C  CB    . TRP B 1 232 ? -11.571 16.754  -56.943  1.00 35.83  ? 232 TRP B CB    1 
ATOM   5859  C  CG    . TRP B 1 232 ? -11.673 15.479  -57.721  1.00 40.63  ? 232 TRP B CG    1 
ATOM   5860  C  CD1   . TRP B 1 232 ? -10.702 14.877  -58.471  1.00 41.76  ? 232 TRP B CD1   1 
ATOM   5861  C  CD2   . TRP B 1 232 ? -12.817 14.606  -57.777  1.00 43.04  ? 232 TRP B CD2   1 
ATOM   5862  N  NE1   . TRP B 1 232 ? -11.171 13.707  -59.017  1.00 43.60  ? 232 TRP B NE1   1 
ATOM   5863  C  CE2   . TRP B 1 232 ? -12.467 13.516  -58.611  1.00 41.63  ? 232 TRP B CE2   1 
ATOM   5864  C  CE3   . TRP B 1 232 ? -14.109 14.658  -57.235  1.00 43.91  ? 232 TRP B CE3   1 
ATOM   5865  C  CZ2   . TRP B 1 232 ? -13.354 12.481  -58.894  1.00 43.05  ? 232 TRP B CZ2   1 
ATOM   5866  C  CZ3   . TRP B 1 232 ? -14.981 13.626  -57.508  1.00 47.45  ? 232 TRP B CZ3   1 
ATOM   5867  C  CH2   . TRP B 1 232 ? -14.607 12.553  -58.325  1.00 50.03  ? 232 TRP B CH2   1 
ATOM   5868  N  N     . LEU B 1 233 ? -9.884  19.534  -56.863  1.00 33.92  ? 233 LEU B N     1 
ATOM   5869  C  CA    . LEU B 1 233 ? -9.793  20.941  -56.513  1.00 37.59  ? 233 LEU B CA    1 
ATOM   5870  C  C     . LEU B 1 233 ? -10.843 21.698  -57.308  1.00 40.32  ? 233 LEU B C     1 
ATOM   5871  O  O     . LEU B 1 233 ? -11.125 21.389  -58.462  1.00 42.10  ? 233 LEU B O     1 
ATOM   5872  C  CB    . LEU B 1 233 ? -8.395  21.487  -56.856  1.00 39.95  ? 233 LEU B CB    1 
ATOM   5873  C  CG    . LEU B 1 233 ? -7.227  20.782  -56.176  1.00 38.72  ? 233 LEU B CG    1 
ATOM   5874  C  CD1   . LEU B 1 233 ? -5.897  21.381  -56.599  1.00 38.30  ? 233 LEU B CD1   1 
ATOM   5875  C  CD2   . LEU B 1 233 ? -7.385  20.831  -54.670  1.00 36.69  ? 233 LEU B CD2   1 
ATOM   5876  N  N     . MET B 1 234 ? -11.388 22.736  -56.694  1.00 39.97  ? 234 MET B N     1 
ATOM   5877  C  CA    . MET B 1 234 ? -12.418 23.517  -57.342  1.00 39.33  ? 234 MET B CA    1 
ATOM   5878  C  C     . MET B 1 234 ? -11.768 24.500  -58.306  1.00 42.70  ? 234 MET B C     1 
ATOM   5879  O  O     . MET B 1 234 ? -10.792 25.141  -57.934  1.00 43.44  ? 234 MET B O     1 
ATOM   5880  C  CB    . MET B 1 234 ? -13.202 24.317  -56.314  1.00 40.92  ? 234 MET B CB    1 
ATOM   5881  C  CG    . MET B 1 234 ? -14.225 25.262  -56.929  1.00 46.23  ? 234 MET B CG    1 
ATOM   5882  S  SD    . MET B 1 234 ? -15.468 25.653  -55.708  1.00 47.05  ? 234 MET B SD    1 
ATOM   5883  C  CE    . MET B 1 234 ? -14.829 27.127  -54.939  1.00 50.18  ? 234 MET B CE    1 
ATOM   5884  N  N     . PRO B 1 235 ? -12.304 24.670  -59.538  1.00 37.60  ? 235 PRO B N     1 
ATOM   5885  C  CA    . PRO B 1 235 ? -11.877 25.750  -60.419  1.00 38.91  ? 235 PRO B CA    1 
ATOM   5886  C  C     . PRO B 1 235 ? -12.241 27.089  -59.804  1.00 40.82  ? 235 PRO B C     1 
ATOM   5887  O  O     . PRO B 1 235 ? -13.275 27.199  -59.188  1.00 40.59  ? 235 PRO B O     1 
ATOM   5888  C  CB    . PRO B 1 235 ? -12.681 25.524  -61.706  1.00 39.84  ? 235 PRO B CB    1 
ATOM   5889  C  CG    . PRO B 1 235 ? -12.981 24.049  -61.664  1.00 41.10  ? 235 PRO B CG    1 
ATOM   5890  C  CD    . PRO B 1 235 ? -13.245 23.758  -60.198  1.00 36.43  ? 235 PRO B CD    1 
ATOM   5891  N  N     . GLU B 1 236 ? -11.392 28.095  -59.978  1.00 37.76  ? 236 GLU B N     1 
ATOM   5892  C  CA    . GLU B 1 236 ? -11.734 29.429  -59.536  1.00 42.90  ? 236 GLU B CA    1 
ATOM   5893  C  C     . GLU B 1 236 ? -13.076 29.807  -60.136  1.00 40.59  ? 236 GLU B C     1 
ATOM   5894  O  O     . GLU B 1 236 ? -13.224 29.811  -61.335  1.00 46.58  ? 236 GLU B O     1 
ATOM   5895  C  CB    . GLU B 1 236 ? -10.651 30.400  -60.001  1.00 42.89  ? 236 GLU B CB    1 
ATOM   5896  C  CG    . GLU B 1 236 ? -10.874 31.833  -59.588  1.00 49.77  ? 236 GLU B CG    1 
ATOM   5897  C  CD    . GLU B 1 236 ? -9.690  32.740  -59.902  1.00 59.48  ? 236 GLU B CD    1 
ATOM   5898  O  OE1   . GLU B 1 236 ? -8.661  32.239  -60.384  1.00 60.74  ? 236 GLU B OE1   1 
ATOM   5899  O  OE2   . GLU B 1 236 ? -9.791  33.945  -59.650  1.00 72.07  ? 236 GLU B OE2   1 
ATOM   5900  N  N     . PRO B 1 237 ? -14.102 30.161  -59.354  1.00 42.05  ? 237 PRO B N     1 
ATOM   5901  C  CA    . PRO B 1 237 ? -15.394 30.517  -59.949  1.00 41.64  ? 237 PRO B CA    1 
ATOM   5902  C  C     . PRO B 1 237 ? -15.438 31.944  -60.510  1.00 42.90  ? 237 PRO B C     1 
ATOM   5903  O  O     . PRO B 1 237 ? -14.565 32.757  -60.247  1.00 42.67  ? 237 PRO B O     1 
ATOM   5904  C  CB    . PRO B 1 237 ? -16.319 30.415  -58.739  1.00 43.95  ? 237 PRO B CB    1 
ATOM   5905  C  CG    . PRO B 1 237 ? -15.444 30.854  -57.586  1.00 43.61  ? 237 PRO B CG    1 
ATOM   5906  C  CD    . PRO B 1 237 ? -14.072 30.284  -57.893  1.00 40.07  ? 237 PRO B CD    1 
ATOM   5907  N  N     . ALA B 1 238 ? -16.505 32.255  -61.234  1.00 40.34  ? 238 ALA B N     1 
ATOM   5908  C  CA    . ALA B 1 238 ? -16.665 33.525  -61.920  1.00 46.72  ? 238 ALA B CA    1 
ATOM   5909  C  C     . ALA B 1 238 ? -16.994 34.662  -60.950  1.00 47.81  ? 238 ALA B C     1 
ATOM   5910  O  O     . ALA B 1 238 ? -16.941 35.819  -61.329  1.00 53.17  ? 238 ALA B O     1 
ATOM   5911  C  CB    . ALA B 1 238 ? -17.742 33.375  -62.977  1.00 46.38  ? 238 ALA B CB    1 
ATOM   5912  N  N     . GLY B 1 239 ? -17.378 34.340  -59.713  1.00 47.73  ? 239 GLY B N     1 
ATOM   5913  C  CA    . GLY B 1 239 ? -17.674 35.349  -58.711  1.00 38.81  ? 239 GLY B CA    1 
ATOM   5914  C  C     . GLY B 1 239 ? -17.691 34.718  -57.325  1.00 41.43  ? 239 GLY B C     1 
ATOM   5915  O  O     . GLY B 1 239 ? -17.770 33.502  -57.208  1.00 40.01  ? 239 GLY B O     1 
ATOM   5916  N  N     . TYR B 1 240 ? -17.632 35.567  -56.298  1.00 44.08  ? 240 TYR B N     1 
ATOM   5917  C  CA    . TYR B 1 240 ? -17.560 35.145  -54.908  1.00 42.60  ? 240 TYR B CA    1 
ATOM   5918  C  C     . TYR B 1 240 ? -18.133 36.253  -54.030  1.00 43.85  ? 240 TYR B C     1 
ATOM   5919  O  O     . TYR B 1 240 ? -17.674 37.384  -54.099  1.00 43.82  ? 240 TYR B O     1 
ATOM   5920  C  CB    . TYR B 1 240 ? -16.109 34.855  -54.542  1.00 43.04  ? 240 TYR B CB    1 
ATOM   5921  C  CG    . TYR B 1 240 ? -15.867 34.502  -53.095  1.00 45.82  ? 240 TYR B CG    1 
ATOM   5922  C  CD1   . TYR B 1 240 ? -16.462 33.391  -52.518  1.00 40.13  ? 240 TYR B CD1   1 
ATOM   5923  C  CD2   . TYR B 1 240 ? -15.042 35.287  -52.302  1.00 40.82  ? 240 TYR B CD2   1 
ATOM   5924  C  CE1   . TYR B 1 240 ? -16.247 33.072  -51.187  1.00 42.39  ? 240 TYR B CE1   1 
ATOM   5925  C  CE2   . TYR B 1 240 ? -14.808 34.969  -50.976  1.00 42.18  ? 240 TYR B CE2   1 
ATOM   5926  C  CZ    . TYR B 1 240 ? -15.404 33.855  -50.414  1.00 40.45  ? 240 TYR B CZ    1 
ATOM   5927  O  OH    . TYR B 1 240 ? -15.169 33.537  -49.089  1.00 39.92  ? 240 TYR B OH    1 
ATOM   5928  N  N     . ARG B 1 241 ? -19.159 35.929  -53.232  1.00 42.74  ? 241 ARG B N     1 
ATOM   5929  C  CA    . ARG B 1 241 ? -19.714 36.879  -52.290  1.00 44.69  ? 241 ARG B CA    1 
ATOM   5930  C  C     . ARG B 1 241 ? -19.962 36.188  -50.947  1.00 41.62  ? 241 ARG B C     1 
ATOM   5931  O  O     . ARG B 1 241 ? -20.944 35.466  -50.769  1.00 36.60  ? 241 ARG B O     1 
ATOM   5932  C  CB    . ARG B 1 241 ? -20.980 37.489  -52.888  1.00 46.18  ? 241 ARG B CB    1 
ATOM   5933  C  CG    . ARG B 1 241 ? -20.722 38.423  -54.060  1.00 52.34  ? 241 ARG B CG    1 
ATOM   5934  C  CD    . ARG B 1 241 ? -20.199 39.770  -53.593  1.00 54.26  ? 241 ARG B CD    1 
ATOM   5935  N  NE    . ARG B 1 241 ? -21.234 40.597  -52.976  1.00 55.88  ? 241 ARG B NE    1 
ATOM   5936  C  CZ    . ARG B 1 241 ? -20.993 41.660  -52.217  1.00 57.70  ? 241 ARG B CZ    1 
ATOM   5937  N  NH1   . ARG B 1 241 ? -19.783 41.869  -51.725  1.00 55.32  ? 241 ARG B NH1   1 
ATOM   5938  N  NH2   . ARG B 1 241 ? -21.980 42.477  -51.898  1.00 59.91  ? 241 ARG B NH2   1 
ATOM   5939  N  N     . PRO B 1 242 ? -19.072 36.376  -49.953  1.00 39.84  ? 242 PRO B N     1 
ATOM   5940  C  CA    . PRO B 1 242 ? -19.314 35.846  -48.610  1.00 38.70  ? 242 PRO B CA    1 
ATOM   5941  C  C     . PRO B 1 242 ? -20.211 36.786  -47.812  1.00 38.82  ? 242 PRO B C     1 
ATOM   5942  O  O     . PRO B 1 242 ? -20.211 37.989  -48.024  1.00 43.55  ? 242 PRO B O     1 
ATOM   5943  C  CB    . PRO B 1 242 ? -17.892 35.737  -48.055  1.00 40.14  ? 242 PRO B CB    1 
ATOM   5944  C  CG    . PRO B 1 242 ? -17.161 36.910  -48.692  1.00 39.91  ? 242 PRO B CG    1 
ATOM   5945  C  CD    . PRO B 1 242 ? -17.762 37.047  -50.076  1.00 41.56  ? 242 PRO B CD    1 
ATOM   5946  N  N     . TYR B 1 243 ? -20.999 36.208  -46.910  1.00 39.14  ? 243 TYR B N     1 
ATOM   5947  C  CA    . TYR B 1 243 ? -22.019 36.932  -46.178  1.00 37.40  ? 243 TYR B CA    1 
ATOM   5948  C  C     . TYR B 1 243 ? -22.105 36.377  -44.758  1.00 36.73  ? 243 TYR B C     1 
ATOM   5949  O  O     . TYR B 1 243 ? -21.681 35.255  -44.474  1.00 38.50  ? 243 TYR B O     1 
ATOM   5950  C  CB    . TYR B 1 243 ? -23.365 36.843  -46.915  1.00 35.70  ? 243 TYR B CB    1 
ATOM   5951  C  CG    . TYR B 1 243 ? -23.905 35.444  -47.040  1.00 36.58  ? 243 TYR B CG    1 
ATOM   5952  C  CD1   . TYR B 1 243 ? -24.458 34.793  -45.947  1.00 42.87  ? 243 TYR B CD1   1 
ATOM   5953  C  CD2   . TYR B 1 243 ? -23.854 34.758  -48.243  1.00 39.36  ? 243 TYR B CD2   1 
ATOM   5954  C  CE1   . TYR B 1 243 ? -24.930 33.493  -46.043  1.00 43.06  ? 243 TYR B CE1   1 
ATOM   5955  C  CE2   . TYR B 1 243 ? -24.318 33.457  -48.363  1.00 40.07  ? 243 TYR B CE2   1 
ATOM   5956  C  CZ    . TYR B 1 243 ? -24.871 32.830  -47.260  1.00 42.84  ? 243 TYR B CZ    1 
ATOM   5957  O  OH    . TYR B 1 243 ? -25.348 31.561  -47.342  1.00 41.88  ? 243 TYR B OH    1 
ATOM   5958  N  N     . LEU B 1 244 ? -22.636 37.220  -43.882  1.00 36.29  ? 244 LEU B N     1 
ATOM   5959  C  CA    . LEU B 1 244 ? -22.922 36.907  -42.498  1.00 38.77  ? 244 LEU B CA    1 
ATOM   5960  C  C     . LEU B 1 244 ? -24.354 37.350  -42.246  1.00 41.37  ? 244 LEU B C     1 
ATOM   5961  O  O     . LEU B 1 244 ? -24.706 38.514  -42.503  1.00 45.34  ? 244 LEU B O     1 
ATOM   5962  C  CB    . LEU B 1 244 ? -21.956 37.673  -41.574  1.00 42.58  ? 244 LEU B CB    1 
ATOM   5963  C  CG    . LEU B 1 244 ? -22.390 37.799  -40.113  1.00 42.61  ? 244 LEU B CG    1 
ATOM   5964  C  CD1   . LEU B 1 244 ? -22.382 36.430  -39.449  1.00 46.72  ? 244 LEU B CD1   1 
ATOM   5965  C  CD2   . LEU B 1 244 ? -21.517 38.775  -39.326  1.00 44.01  ? 244 LEU B CD2   1 
ATOM   5966  N  N     . ILE B 1 245 ? -25.133 36.441  -41.667  1.00 41.26  ? 245 ILE B N     1 
ATOM   5967  C  CA    . ILE B 1 245 ? -26.464 36.761  -41.188  1.00 41.03  ? 245 ILE B CA    1 
ATOM   5968  C  C     . ILE B 1 245 ? -26.514 36.524  -39.682  1.00 43.76  ? 245 ILE B C     1 
ATOM   5969  O  O     . ILE B 1 245 ? -26.273 35.402  -39.241  1.00 37.79  ? 245 ILE B O     1 
ATOM   5970  C  CB    . ILE B 1 245 ? -27.525 35.914  -41.913  1.00 43.86  ? 245 ILE B CB    1 
ATOM   5971  C  CG1   . ILE B 1 245 ? -27.308 35.909  -43.431  1.00 43.04  ? 245 ILE B CG1   1 
ATOM   5972  C  CG2   . ILE B 1 245 ? -28.918 36.390  -41.511  1.00 40.63  ? 245 ILE B CG2   1 
ATOM   5973  C  CD1   . ILE B 1 245 ? -28.292 35.078  -44.229  1.00 41.25  ? 245 ILE B CD1   1 
ATOM   5974  N  N     . THR B 1 246 ? -26.882 37.568  -38.919  1.00 37.48  ? 246 THR B N     1 
ATOM   5975  C  CA    . THR B 1 246 ? -26.898 37.490  -37.466  1.00 39.89  ? 246 THR B CA    1 
ATOM   5976  C  C     . THR B 1 246 ? -28.331 37.428  -36.958  1.00 37.57  ? 246 THR B C     1 
ATOM   5977  O  O     . THR B 1 246 ? -29.222 37.995  -37.574  1.00 39.92  ? 246 THR B O     1 
ATOM   5978  C  CB    . THR B 1 246 ? -26.191 38.685  -36.815  1.00 39.41  ? 246 THR B CB    1 
ATOM   5979  O  OG1   . THR B 1 246 ? -26.934 39.884  -37.067  1.00 39.39  ? 246 THR B OG1   1 
ATOM   5980  C  CG2   . THR B 1 246 ? -24.769 38.834  -37.303  1.00 37.50  ? 246 THR B CG2   1 
ATOM   5981  N  N     . PHE B 1 247 ? -28.512 36.728  -35.835  1.00 38.81  ? 247 PHE B N     1 
ATOM   5982  C  CA    . PHE B 1 247 ? -29.786 36.642  -35.143  1.00 42.76  ? 247 PHE B CA    1 
ATOM   5983  C  C     . PHE B 1 247 ? -29.602 37.015  -33.674  1.00 43.19  ? 247 PHE B C     1 
ATOM   5984  O  O     . PHE B 1 247 ? -28.630 36.588  -33.057  1.00 45.12  ? 247 PHE B O     1 
ATOM   5985  C  CB    . PHE B 1 247 ? -30.341 35.226  -35.256  1.00 42.57  ? 247 PHE B CB    1 
ATOM   5986  C  CG    . PHE B 1 247 ? -30.345 34.736  -36.676  1.00 40.30  ? 247 PHE B CG    1 
ATOM   5987  C  CD1   . PHE B 1 247 ? -29.239 34.079  -37.199  1.00 41.40  ? 247 PHE B CD1   1 
ATOM   5988  C  CD2   . PHE B 1 247 ? -31.436 34.975  -37.496  1.00 37.61  ? 247 PHE B CD2   1 
ATOM   5989  C  CE1   . PHE B 1 247 ? -29.252 33.625  -38.506  1.00 44.95  ? 247 PHE B CE1   1 
ATOM   5990  C  CE2   . PHE B 1 247 ? -31.417 34.575  -38.821  1.00 37.44  ? 247 PHE B CE2   1 
ATOM   5991  C  CZ    . PHE B 1 247 ? -30.331 33.896  -39.322  1.00 38.67  ? 247 PHE B CZ    1 
ATOM   5992  N  N     . GLU B 1 248 ? -30.575 37.758  -33.129  1.00 41.97  ? 248 GLU B N     1 
ATOM   5993  C  CA    . GLU B 1 248 ? -30.444 38.402  -31.829  1.00 46.63  ? 248 GLU B CA    1 
ATOM   5994  C  C     . GLU B 1 248 ? -30.673 37.431  -30.685  1.00 44.96  ? 248 GLU B C     1 
ATOM   5995  O  O     . GLU B 1 248 ? -30.064 37.603  -29.631  1.00 48.51  ? 248 GLU B O     1 
ATOM   5996  C  CB    . GLU B 1 248 ? -31.467 39.519  -31.623  1.00 49.61  ? 248 GLU B CB    1 
ATOM   5997  C  CG    . GLU B 1 248 ? -31.164 40.780  -32.401  1.00 60.92  ? 248 GLU B CG    1 
ATOM   5998  C  CD    . GLU B 1 248 ? -29.890 41.504  -31.998  1.00 71.45  ? 248 GLU B CD    1 
ATOM   5999  O  OE1   . GLU B 1 248 ? -29.819 41.984  -30.853  1.00 82.43  ? 248 GLU B OE1   1 
ATOM   6000  O  OE2   . GLU B 1 248 ? -28.966 41.596  -32.837  1.00 85.51  ? 248 GLU B OE2   1 
ATOM   6001  N  N     . ASN B 1 249 ? -31.547 36.432  -30.868  1.00 41.20  ? 249 ASN B N     1 
ATOM   6002  C  CA    . ASN B 1 249 ? -32.037 35.653  -29.733  1.00 41.89  ? 249 ASN B CA    1 
ATOM   6003  C  C     . ASN B 1 249 ? -31.506 34.223  -29.739  1.00 36.80  ? 249 ASN B C     1 
ATOM   6004  O  O     . ASN B 1 249 ? -31.388 33.626  -30.783  1.00 39.05  ? 249 ASN B O     1 
ATOM   6005  C  CB    . ASN B 1 249 ? -33.560 35.607  -29.710  1.00 40.91  ? 249 ASN B CB    1 
ATOM   6006  C  CG    . ASN B 1 249 ? -34.128 37.003  -29.688  1.00 47.70  ? 249 ASN B CG    1 
ATOM   6007  O  OD1   . ASN B 1 249 ? -34.097 37.661  -28.657  1.00 53.45  ? 249 ASN B OD1   1 
ATOM   6008  N  ND2   . ASN B 1 249 ? -34.603 37.471  -30.824  1.00 46.72  ? 249 ASN B ND2   1 
ATOM   6009  N  N     . GLU B 1 250 ? -31.264 33.653  -28.553  1.00 40.51  ? 250 GLU B N     1 
ATOM   6010  C  CA    . GLU B 1 250 ? -30.721 32.306  -28.476  1.00 42.28  ? 250 GLU B CA    1 
ATOM   6011  C  C     . GLU B 1 250 ? -31.722 31.314  -29.066  1.00 44.42  ? 250 GLU B C     1 
ATOM   6012  O  O     . GLU B 1 250 ? -31.303 30.361  -29.701  1.00 47.60  ? 250 GLU B O     1 
ATOM   6013  C  CB    . GLU B 1 250 ? -30.308 31.940  -27.053  1.00 45.53  ? 250 GLU B CB    1 
ATOM   6014  C  CG    . GLU B 1 250 ? -31.449 31.872  -26.062  1.00 45.54  ? 250 GLU B CG    1 
ATOM   6015  C  CD    . GLU B 1 250 ? -31.014 31.487  -24.660  1.00 54.98  ? 250 GLU B CD    1 
ATOM   6016  O  OE1   . GLU B 1 250 ? -29.879 30.977  -24.498  1.00 54.82  ? 250 GLU B OE1   1 
ATOM   6017  O  OE2   . GLU B 1 250 ? -31.805 31.704  -23.733  1.00 58.80  ? 250 GLU B OE2   1 
ATOM   6018  N  N     . ASP B 1 251 ? -33.033 31.558  -28.891  1.00 45.07  ? 251 ASP B N     1 
ATOM   6019  C  CA    . ASP B 1 251 ? -34.066 30.628  -29.326  1.00 44.78  ? 251 ASP B CA    1 
ATOM   6020  C  C     . ASP B 1 251 ? -34.255 30.658  -30.834  1.00 41.52  ? 251 ASP B C     1 
ATOM   6021  O  O     . ASP B 1 251 ? -34.925 29.800  -31.392  1.00 45.56  ? 251 ASP B O     1 
ATOM   6022  C  CB    . ASP B 1 251 ? -35.402 30.909  -28.645  1.00 43.89  ? 251 ASP B CB    1 
ATOM   6023  C  CG    . ASP B 1 251 ? -35.434 30.434  -27.204  1.00 55.01  ? 251 ASP B CG    1 
ATOM   6024  O  OD1   . ASP B 1 251 ? -34.492 29.724  -26.796  1.00 55.60  ? 251 ASP B OD1   1 
ATOM   6025  O  OD2   . ASP B 1 251 ? -36.400 30.775  -26.505  1.00 62.02  ? 251 ASP B OD2   1 
ATOM   6026  N  N     . ASP B 1 252 ? -33.660 31.638  -31.505  1.00 41.44  ? 252 ASP B N     1 
ATOM   6027  C  CA    . ASP B 1 252 ? -33.797 31.753  -32.945  1.00 40.08  ? 252 ASP B CA    1 
ATOM   6028  C  C     . ASP B 1 252 ? -33.191 30.533  -33.642  1.00 40.85  ? 252 ASP B C     1 
ATOM   6029  O  O     . ASP B 1 252 ? -33.505 30.259  -34.796  1.00 38.00  ? 252 ASP B O     1 
ATOM   6030  C  CB    . ASP B 1 252 ? -33.133 33.025  -33.472  1.00 44.14  ? 252 ASP B CB    1 
ATOM   6031  C  CG    . ASP B 1 252 ? -33.920 34.319  -33.310  1.00 51.49  ? 252 ASP B CG    1 
ATOM   6032  O  OD1   . ASP B 1 252 ? -35.158 34.251  -33.153  1.00 43.19  ? 252 ASP B OD1   1 
ATOM   6033  O  OD2   . ASP B 1 252 ? -33.276 35.395  -33.360  1.00 44.99  ? 252 ASP B OD2   1 
ATOM   6034  N  N     . ILE B 1 253 ? -32.300 29.803  -32.969  1.00 44.57  ? 253 ILE B N     1 
ATOM   6035  C  CA    . ILE B 1 253 ? -31.587 28.742  -33.656  1.00 44.16  ? 253 ILE B CA    1 
ATOM   6036  C  C     . ILE B 1 253 ? -32.585 27.728  -34.206  1.00 42.19  ? 253 ILE B C     1 
ATOM   6037  O  O     . ILE B 1 253 ? -32.303 27.073  -35.202  1.00 38.60  ? 253 ILE B O     1 
ATOM   6038  C  CB    . ILE B 1 253 ? -30.509 28.081  -32.771  1.00 44.62  ? 253 ILE B CB    1 
ATOM   6039  C  CG1   . ILE B 1 253 ? -29.551 27.255  -33.628  1.00 41.72  ? 253 ILE B CG1   1 
ATOM   6040  C  CG2   . ILE B 1 253 ? -31.096 27.244  -31.643  1.00 45.98  ? 253 ILE B CG2   1 
ATOM   6041  C  CD1   . ILE B 1 253 ? -29.062 27.985  -34.851  1.00 43.19  ? 253 ILE B CD1   1 
ATOM   6042  N  N     . GLU B 1 254 ? -33.765 27.638  -33.585  1.00 43.80  ? 254 GLU B N     1 
ATOM   6043  C  CA    . GLU B 1 254 ? -34.719 26.603  -33.951  1.00 44.49  ? 254 GLU B CA    1 
ATOM   6044  C  C     . GLU B 1 254 ? -35.309 26.901  -35.330  1.00 42.88  ? 254 GLU B C     1 
ATOM   6045  O  O     . GLU B 1 254 ? -35.265 26.047  -36.209  1.00 46.26  ? 254 GLU B O     1 
ATOM   6046  C  CB    . GLU B 1 254 ? -35.750 26.470  -32.833  1.00 44.55  ? 254 GLU B CB    1 
ATOM   6047  C  CG    . GLU B 1 254 ? -36.846 25.480  -33.135  1.00 46.63  ? 254 GLU B CG    1 
ATOM   6048  C  CD    . GLU B 1 254 ? -37.898 25.287  -32.049  1.00 48.24  ? 254 GLU B CD    1 
ATOM   6049  O  OE1   . GLU B 1 254 ? -37.833 25.941  -30.984  1.00 51.27  ? 254 GLU B OE1   1 
ATOM   6050  O  OE2   . GLU B 1 254 ? -38.768 24.452  -32.267  1.00 51.49  ? 254 GLU B OE2   1 
ATOM   6051  N  N     . THR B 1 255 ? -35.860 28.107  -35.528  1.00 43.23  ? 255 THR B N     1 
ATOM   6052  C  CA    . THR B 1 255 ? -36.435 28.459  -36.816  1.00 40.83  ? 255 THR B CA    1 
ATOM   6053  C  C     . THR B 1 255 ? -35.335 28.585  -37.874  1.00 37.68  ? 255 THR B C     1 
ATOM   6054  O  O     . THR B 1 255 ? -35.599 28.323  -39.043  1.00 42.37  ? 255 THR B O     1 
ATOM   6055  C  CB    . THR B 1 255 ? -37.287 29.736  -36.758  1.00 40.19  ? 255 THR B CB    1 
ATOM   6056  O  OG1   . THR B 1 255 ? -38.069 29.811  -37.948  1.00 45.40  ? 255 THR B OG1   1 
ATOM   6057  C  CG2   . THR B 1 255 ? -36.467 31.007  -36.679  1.00 44.07  ? 255 THR B CG2   1 
ATOM   6058  N  N     . VAL B 1 256 ? -34.130 29.005  -37.474  1.00 39.63  ? 256 VAL B N     1 
ATOM   6059  C  CA    . VAL B 1 256 ? -33.030 29.203  -38.415  1.00 37.30  ? 256 VAL B CA    1 
ATOM   6060  C  C     . VAL B 1 256 ? -32.676 27.859  -39.030  1.00 35.24  ? 256 VAL B C     1 
ATOM   6061  O  O     . VAL B 1 256 ? -32.492 27.769  -40.229  1.00 38.66  ? 256 VAL B O     1 
ATOM   6062  C  CB    . VAL B 1 256 ? -31.786 29.842  -37.778  1.00 39.71  ? 256 VAL B CB    1 
ATOM   6063  C  CG1   . VAL B 1 256 ? -30.545 29.606  -38.637  1.00 40.77  ? 256 VAL B CG1   1 
ATOM   6064  C  CG2   . VAL B 1 256 ? -31.991 31.333  -37.538  1.00 41.91  ? 256 VAL B CG2   1 
ATOM   6065  N  N     . THR B 1 257 ? -32.573 26.823  -38.194  1.00 39.41  ? 257 THR B N     1 
ATOM   6066  C  CA    . THR B 1 257 ? -32.241 25.498  -38.681  1.00 36.41  ? 257 THR B CA    1 
ATOM   6067  C  C     . THR B 1 257 ? -33.341 24.956  -39.596  1.00 40.78  ? 257 THR B C     1 
ATOM   6068  O  O     . THR B 1 257 ? -33.041 24.395  -40.640  1.00 41.02  ? 257 THR B O     1 
ATOM   6069  C  CB    . THR B 1 257 ? -31.959 24.573  -37.505  1.00 35.34  ? 257 THR B CB    1 
ATOM   6070  O  OG1   . THR B 1 257 ? -30.866 25.142  -36.778  1.00 40.62  ? 257 THR B OG1   1 
ATOM   6071  C  CG2   . THR B 1 257 ? -31.612 23.179  -37.970  1.00 37.91  ? 257 THR B CG2   1 
ATOM   6072  N  N     . GLU B 1 258 ? -34.617 25.170  -39.231  1.00 40.23  ? 258 GLU B N     1 
ATOM   6073  C  CA    . GLU B 1 258 ? -35.729 24.790  -40.090  1.00 42.12  ? 258 GLU B CA    1 
ATOM   6074  C  C     . GLU B 1 258 ? -35.574 25.412  -41.474  1.00 37.87  ? 258 GLU B C     1 
ATOM   6075  O  O     . GLU B 1 258 ? -35.747 24.738  -42.477  1.00 41.28  ? 258 GLU B O     1 
ATOM   6076  C  CB    . GLU B 1 258 ? -37.077 25.200  -39.486  1.00 41.35  ? 258 GLU B CB    1 
ATOM   6077  C  CG    . GLU B 1 258 ? -37.488 24.328  -38.331  1.00 38.62  ? 258 GLU B CG    1 
ATOM   6078  C  CD    . GLU B 1 258 ? -37.752 22.886  -38.723  1.00 43.19  ? 258 GLU B CD    1 
ATOM   6079  O  OE1   . GLU B 1 258 ? -38.675 22.671  -39.514  1.00 40.84  ? 258 GLU B OE1   1 
ATOM   6080  O  OE2   . GLU B 1 258 ? -37.034 21.983  -38.233  1.00 43.13  ? 258 GLU B OE2   1 
ATOM   6081  N  N     . ARG B 1 259 ? -35.215 26.693  -41.536  1.00 41.80  ? 259 ARG B N     1 
ATOM   6082  C  CA    . ARG B 1 259 ? -35.102 27.373  -42.811  1.00 39.26  ? 259 ARG B CA    1 
ATOM   6083  C  C     . ARG B 1 259 ? -33.844 26.945  -43.569  1.00 38.93  ? 259 ARG B C     1 
ATOM   6084  O  O     . ARG B 1 259 ? -33.836 26.990  -44.794  1.00 40.03  ? 259 ARG B O     1 
ATOM   6085  C  CB    . ARG B 1 259 ? -35.110 28.882  -42.570  1.00 45.33  ? 259 ARG B CB    1 
ATOM   6086  C  CG    . ARG B 1 259 ? -36.412 29.377  -41.964  1.00 50.03  ? 259 ARG B CG    1 
ATOM   6087  C  CD    . ARG B 1 259 ? -36.129 30.508  -41.001  1.00 54.50  ? 259 ARG B CD    1 
ATOM   6088  N  NE    . ARG B 1 259 ? -37.335 30.950  -40.319  1.00 56.39  ? 259 ARG B NE    1 
ATOM   6089  C  CZ    . ARG B 1 259 ? -38.031 32.012  -40.697  1.00 51.40  ? 259 ARG B CZ    1 
ATOM   6090  N  NH1   . ARG B 1 259 ? -37.723 32.610  -41.828  1.00 53.20  ? 259 ARG B NH1   1 
ATOM   6091  N  NH2   . ARG B 1 259 ? -39.044 32.452  -39.977  1.00 55.02  ? 259 ARG B NH2   1 
ATOM   6092  N  N     . LEU B 1 260 ? -32.778 26.558  -42.865  1.00 37.07  ? 260 LEU B N     1 
ATOM   6093  C  CA    . LEU B 1 260 ? -31.549 26.131  -43.532  1.00 38.61  ? 260 LEU B CA    1 
ATOM   6094  C  C     . LEU B 1 260 ? -31.766 24.789  -44.230  1.00 41.58  ? 260 LEU B C     1 
ATOM   6095  O  O     . LEU B 1 260 ? -31.190 24.536  -45.293  1.00 39.21  ? 260 LEU B O     1 
ATOM   6096  C  CB    . LEU B 1 260 ? -30.422 26.020  -42.497  1.00 39.60  ? 260 LEU B CB    1 
ATOM   6097  C  CG    . LEU B 1 260 ? -29.765 27.339  -42.071  1.00 41.55  ? 260 LEU B CG    1 
ATOM   6098  C  CD1   . LEU B 1 260 ? -28.846 27.128  -40.864  1.00 43.56  ? 260 LEU B CD1   1 
ATOM   6099  C  CD2   . LEU B 1 260 ? -28.966 27.964  -43.216  1.00 42.03  ? 260 LEU B CD2   1 
ATOM   6100  N  N     . ARG B 1 261 ? -32.623 23.934  -43.648  1.00 39.26  ? 261 ARG B N     1 
ATOM   6101  C  CA    . ARG B 1 261 ? -32.722 22.564  -44.116  1.00 43.23  ? 261 ARG B CA    1 
ATOM   6102  C  C     . ARG B 1 261 ? -32.938 22.525  -45.633  1.00 41.71  ? 261 ARG B C     1 
ATOM   6103  O  O     . ARG B 1 261 ? -32.079 22.009  -46.340  1.00 38.22  ? 261 ARG B O     1 
ATOM   6104  C  CB    . ARG B 1 261 ? -33.791 21.769  -43.373  1.00 43.53  ? 261 ARG B CB    1 
ATOM   6105  C  CG    . ARG B 1 261 ? -34.149 20.452  -44.059  1.00 45.58  ? 261 ARG B CG    1 
ATOM   6106  C  CD    . ARG B 1 261 ? -35.162 19.639  -43.271  1.00 46.38  ? 261 ARG B CD    1 
ATOM   6107  N  NE    . ARG B 1 261 ? -36.400 20.388  -43.126  1.00 38.90  ? 261 ARG B NE    1 
ATOM   6108  C  CZ    . ARG B 1 261 ? -36.854 20.873  -41.983  1.00 38.72  ? 261 ARG B CZ    1 
ATOM   6109  N  NH1   . ARG B 1 261 ? -36.164 20.739  -40.870  1.00 40.89  ? 261 ARG B NH1   1 
ATOM   6110  N  NH2   . ARG B 1 261 ? -38.022 21.483  -41.940  1.00 42.14  ? 261 ARG B NH2   1 
ATOM   6111  N  N     . PRO B 1 262 ? -34.038 23.073  -46.204  1.00 41.61  ? 262 PRO B N     1 
ATOM   6112  C  CA    . PRO B 1 262 ? -34.264 22.952  -47.647  1.00 41.26  ? 262 PRO B CA    1 
ATOM   6113  C  C     . PRO B 1 262 ? -33.229 23.682  -48.509  1.00 41.42  ? 262 PRO B C     1 
ATOM   6114  O  O     . PRO B 1 262 ? -32.932 23.250  -49.617  1.00 39.64  ? 262 PRO B O     1 
ATOM   6115  C  CB    . PRO B 1 262 ? -35.685 23.513  -47.853  1.00 40.49  ? 262 PRO B CB    1 
ATOM   6116  C  CG    . PRO B 1 262 ? -35.895 24.428  -46.656  1.00 41.58  ? 262 PRO B CG    1 
ATOM   6117  C  CD    . PRO B 1 262 ? -35.124 23.792  -45.521  1.00 41.25  ? 262 PRO B CD    1 
ATOM   6118  N  N     . LEU B 1 263 ? -32.647 24.772  -47.999  1.00 41.78  ? 263 LEU B N     1 
ATOM   6119  C  CA    . LEU B 1 263 ? -31.601 25.476  -48.722  1.00 41.79  ? 263 LEU B CA    1 
ATOM   6120  C  C     . LEU B 1 263 ? -30.376 24.577  -48.911  1.00 42.73  ? 263 LEU B C     1 
ATOM   6121  O  O     . LEU B 1 263 ? -29.699 24.655  -49.940  1.00 40.73  ? 263 LEU B O     1 
ATOM   6122  C  CB    . LEU B 1 263 ? -31.215 26.734  -47.934  1.00 44.85  ? 263 LEU B CB    1 
ATOM   6123  C  CG    . LEU B 1 263 ? -32.310 27.788  -47.840  1.00 42.06  ? 263 LEU B CG    1 
ATOM   6124  C  CD1   . LEU B 1 263 ? -31.870 28.943  -46.957  1.00 39.37  ? 263 LEU B CD1   1 
ATOM   6125  C  CD2   . LEU B 1 263 ? -32.690 28.280  -49.225  1.00 40.56  ? 263 LEU B CD2   1 
ATOM   6126  N  N     . LYS B 1 264 ? -30.091 23.759  -47.893  1.00 40.32  ? 264 LYS B N     1 
ATOM   6127  C  CA    . LYS B 1 264 ? -28.940 22.873  -47.899  1.00 43.23  ? 264 LYS B CA    1 
ATOM   6128  C  C     . LYS B 1 264 ? -29.210 21.605  -48.713  1.00 40.95  ? 264 LYS B C     1 
ATOM   6129  O  O     . LYS B 1 264 ? -28.405 21.260  -49.579  1.00 36.49  ? 264 LYS B O     1 
ATOM   6130  C  CB    . LYS B 1 264 ? -28.489 22.545  -46.470  1.00 41.13  ? 264 LYS B CB    1 
ATOM   6131  C  CG    . LYS B 1 264 ? -27.608 23.613  -45.828  1.00 42.29  ? 264 LYS B CG    1 
ATOM   6132  C  CD    . LYS B 1 264 ? -26.353 23.916  -46.632  1.00 41.91  ? 264 LYS B CD    1 
ATOM   6133  C  CE    . LYS B 1 264 ? -25.366 22.774  -46.713  1.00 45.15  ? 264 LYS B CE    1 
ATOM   6134  N  NZ    . LYS B 1 264 ? -24.383 23.012  -47.804  1.00 48.99  ? 264 LYS B NZ    1 
ATOM   6135  N  N     . VAL B 1 265 ? -30.322 20.911  -48.454  1.00 42.23  ? 265 VAL B N     1 
ATOM   6136  C  CA    . VAL B 1 265 ? -30.571 19.641  -49.135  1.00 38.15  ? 265 VAL B CA    1 
ATOM   6137  C  C     . VAL B 1 265 ? -30.591 19.874  -50.646  1.00 41.06  ? 265 VAL B C     1 
ATOM   6138  O  O     . VAL B 1 265 ? -30.118 19.041  -51.422  1.00 43.78  ? 265 VAL B O     1 
ATOM   6139  C  CB    . VAL B 1 265 ? -31.877 18.981  -48.647  1.00 37.06  ? 265 VAL B CB    1 
ATOM   6140  C  CG1   . VAL B 1 265 ? -32.182 17.695  -49.410  1.00 38.65  ? 265 VAL B CG1   1 
ATOM   6141  C  CG2   . VAL B 1 265 ? -31.839 18.715  -47.160  1.00 36.47  ? 265 VAL B CG2   1 
ATOM   6142  N  N     . ALA B 1 266 ? -31.145 21.021  -51.062  1.00 38.97  ? 266 ALA B N     1 
ATOM   6143  C  CA    . ALA B 1 266 ? -31.230 21.369  -52.470  1.00 40.32  ? 266 ALA B CA    1 
ATOM   6144  C  C     . ALA B 1 266 ? -29.943 22.005  -53.009  1.00 39.45  ? 266 ALA B C     1 
ATOM   6145  O  O     . ALA B 1 266 ? -29.811 22.164  -54.216  1.00 40.07  ? 266 ALA B O     1 
ATOM   6146  C  CB    . ALA B 1 266 ? -32.425 22.268  -52.716  1.00 40.96  ? 266 ALA B CB    1 
ATOM   6147  N  N     . GLY B 1 267 ? -28.986 22.370  -52.159  1.00 40.66  ? 267 GLY B N     1 
ATOM   6148  C  CA    . GLY B 1 267 ? -27.733 22.921  -52.664  1.00 46.33  ? 267 GLY B CA    1 
ATOM   6149  C  C     . GLY B 1 267 ? -27.803 24.424  -52.967  1.00 44.97  ? 267 GLY B C     1 
ATOM   6150  O  O     . GLY B 1 267 ? -26.914 24.981  -53.597  1.00 41.86  ? 267 GLY B O     1 
ATOM   6151  N  N     . VAL B 1 268 ? -28.830 25.117  -52.474  1.00 41.16  ? 268 VAL B N     1 
ATOM   6152  C  CA    . VAL B 1 268 ? -28.944 26.548  -52.721  1.00 40.90  ? 268 VAL B CA    1 
ATOM   6153  C  C     . VAL B 1 268 ? -27.808 27.289  -52.012  1.00 41.23  ? 268 VAL B C     1 
ATOM   6154  O  O     . VAL B 1 268 ? -27.305 28.265  -52.544  1.00 45.83  ? 268 VAL B O     1 
ATOM   6155  C  CB    . VAL B 1 268 ? -30.323 27.078  -52.293  1.00 40.74  ? 268 VAL B CB    1 
ATOM   6156  C  CG1   . VAL B 1 268 ? -30.414 28.587  -52.390  1.00 43.34  ? 268 VAL B CG1   1 
ATOM   6157  C  CG2   . VAL B 1 268 ? -31.431 26.426  -53.103  1.00 43.23  ? 268 VAL B CG2   1 
ATOM   6158  N  N     . ILE B 1 269 ? -27.492 26.872  -50.778  1.00 38.45  ? 269 ILE B N     1 
ATOM   6159  C  CA    . ILE B 1 269 ? -26.309 27.305  -50.067  1.00 37.39  ? 269 ILE B CA    1 
ATOM   6160  C  C     . ILE B 1 269 ? -25.216 26.340  -50.509  1.00 41.77  ? 269 ILE B C     1 
ATOM   6161  O  O     . ILE B 1 269 ? -25.308 25.144  -50.249  1.00 41.68  ? 269 ILE B O     1 
ATOM   6162  C  CB    . ILE B 1 269 ? -26.544 27.254  -48.544  1.00 39.25  ? 269 ILE B CB    1 
ATOM   6163  C  CG1   . ILE B 1 269 ? -27.533 28.329  -48.082  1.00 45.23  ? 269 ILE B CG1   1 
ATOM   6164  C  CG2   . ILE B 1 269 ? -25.234 27.348  -47.762  1.00 38.36  ? 269 ILE B CG2   1 
ATOM   6165  C  CD1   . ILE B 1 269 ? -28.095 28.087  -46.677  1.00 41.31  ? 269 ILE B CD1   1 
ATOM   6166  N  N     . GLN B 1 270 ? -24.204 26.850  -51.194  1.00 39.67  ? 270 GLN B N     1 
ATOM   6167  C  CA    . GLN B 1 270 ? -23.291 25.999  -51.943  1.00 41.43  ? 270 GLN B CA    1 
ATOM   6168  C  C     . GLN B 1 270 ? -22.153 25.430  -51.089  1.00 38.04  ? 270 GLN B C     1 
ATOM   6169  O  O     . GLN B 1 270 ? -21.545 24.427  -51.450  1.00 40.91  ? 270 GLN B O     1 
ATOM   6170  C  CB    . GLN B 1 270 ? -22.700 26.830  -53.077  1.00 43.90  ? 270 GLN B CB    1 
ATOM   6171  C  CG    . GLN B 1 270 ? -23.734 27.274  -54.099  1.00 40.95  ? 270 GLN B CG    1 
ATOM   6172  C  CD    . GLN B 1 270 ? -23.303 28.540  -54.801  1.00 40.37  ? 270 GLN B CD    1 
ATOM   6173  O  OE1   . GLN B 1 270 ? -23.243 29.622  -54.225  1.00 38.37  ? 270 GLN B OE1   1 
ATOM   6174  N  NE2   . GLN B 1 270 ? -22.980 28.412  -56.073  1.00 42.93  ? 270 GLN B NE2   1 
ATOM   6175  N  N     . ASN B 1 271 ? -21.816 26.063  -49.963  1.00 38.30  ? 271 ASN B N     1 
ATOM   6176  C  CA    . ASN B 1 271 ? -20.790 25.518  -49.079  1.00 39.32  ? 271 ASN B CA    1 
ATOM   6177  C  C     . ASN B 1 271 ? -21.464 24.992  -47.818  1.00 37.19  ? 271 ASN B C     1 
ATOM   6178  O  O     . ASN B 1 271 ? -22.672 25.138  -47.672  1.00 39.09  ? 271 ASN B O     1 
ATOM   6179  C  CB    . ASN B 1 271 ? -19.689 26.535  -48.732  1.00 40.00  ? 271 ASN B CB    1 
ATOM   6180  C  CG    . ASN B 1 271 ? -20.151 27.861  -48.146  1.00 43.39  ? 271 ASN B CG    1 
ATOM   6181  O  OD1   . ASN B 1 271 ? -21.321 28.249  -48.187  1.00 37.60  ? 271 ASN B OD1   1 
ATOM   6182  N  ND2   . ASN B 1 271 ? -19.195 28.623  -47.642  1.00 42.69  ? 271 ASN B ND2   1 
ATOM   6183  N  N     . GLY B 1 272 ? -20.671 24.450  -46.885  1.00 38.46  ? 272 GLY B N     1 
ATOM   6184  C  CA    . GLY B 1 272 ? -21.149 24.123  -45.544  1.00 39.88  ? 272 GLY B CA    1 
ATOM   6185  C  C     . GLY B 1 272 ? -21.713 25.358  -44.847  1.00 42.01  ? 272 GLY B C     1 
ATOM   6186  O  O     . GLY B 1 272 ? -21.125 26.420  -44.920  1.00 44.57  ? 272 GLY B O     1 
ATOM   6187  N  N     . ALA B 1 273 ? -22.901 25.244  -44.244  1.00 40.88  ? 273 ALA B N     1 
ATOM   6188  C  CA    . ALA B 1 273 ? -23.464 26.348  -43.484  1.00 43.74  ? 273 ALA B CA    1 
ATOM   6189  C  C     . ALA B 1 273 ? -22.907 26.264  -42.065  1.00 42.90  ? 273 ALA B C     1 
ATOM   6190  O  O     . ALA B 1 273 ? -22.887 25.190  -41.461  1.00 35.90  ? 273 ALA B O     1 
ATOM   6191  C  CB    . ALA B 1 273 ? -24.983 26.280  -43.500  1.00 44.24  ? 273 ALA B CB    1 
ATOM   6192  N  N     . THR B 1 274 ? -22.408 27.381  -41.540  1.00 38.07  ? 274 THR B N     1 
ATOM   6193  C  CA    . THR B 1 274 ? -21.936 27.385  -40.164  1.00 39.82  ? 274 THR B CA    1 
ATOM   6194  C  C     . THR B 1 274 ? -22.653 28.505  -39.423  1.00 37.12  ? 274 THR B C     1 
ATOM   6195  O  O     . THR B 1 274 ? -22.508 29.669  -39.789  1.00 43.45  ? 274 THR B O     1 
ATOM   6196  C  CB    . THR B 1 274 ? -20.407 27.507  -40.084  1.00 50.71  ? 274 THR B CB    1 
ATOM   6197  O  OG1   . THR B 1 274 ? -20.059 28.892  -40.133  1.00 61.15  ? 274 THR B OG1   1 
ATOM   6198  C  CG2   . THR B 1 274 ? -19.698 26.762  -41.198  1.00 50.14  ? 274 THR B CG2   1 
ATOM   6199  N  N     . VAL B 1 275 ? -23.412 28.124  -38.388  1.00 35.99  ? 275 VAL B N     1 
ATOM   6200  C  CA    . VAL B 1 275 ? -24.069 29.067  -37.512  1.00 43.04  ? 275 VAL B CA    1 
ATOM   6201  C  C     . VAL B 1 275 ? -23.446 28.970  -36.122  1.00 42.73  ? 275 VAL B C     1 
ATOM   6202  O  O     . VAL B 1 275 ? -23.660 27.999  -35.393  1.00 41.16  ? 275 VAL B O     1 
ATOM   6203  C  CB    . VAL B 1 275 ? -25.581 28.834  -37.465  1.00 43.77  ? 275 VAL B CB    1 
ATOM   6204  C  CG1   . VAL B 1 275 ? -26.276 29.974  -36.758  1.00 45.41  ? 275 VAL B CG1   1 
ATOM   6205  C  CG2   . VAL B 1 275 ? -26.153 28.641  -38.857  1.00 44.53  ? 275 VAL B CG2   1 
ATOM   6206  N  N     . ARG B 1 276 ? -22.715 30.035  -35.765  1.00 40.52  ? 276 ARG B N     1 
ATOM   6207  C  CA    . ARG B 1 276 ? -21.796 30.042  -34.638  1.00 36.33  ? 276 ARG B CA    1 
ATOM   6208  C  C     . ARG B 1 276 ? -22.368 30.867  -33.499  1.00 33.78  ? 276 ARG B C     1 
ATOM   6209  O  O     . ARG B 1 276 ? -22.982 31.903  -33.754  1.00 38.10  ? 276 ARG B O     1 
ATOM   6210  C  CB    . ARG B 1 276 ? -20.439 30.554  -35.137  1.00 39.73  ? 276 ARG B CB    1 
ATOM   6211  C  CG    . ARG B 1 276 ? -19.629 29.453  -35.811  1.00 43.84  ? 276 ARG B CG    1 
ATOM   6212  C  CD    . ARG B 1 276 ? -18.510 29.888  -36.733  1.00 56.40  ? 276 ARG B CD    1 
ATOM   6213  N  NE    . ARG B 1 276 ? -17.491 30.614  -36.010  1.00 58.56  ? 276 ARG B NE    1 
ATOM   6214  C  CZ    . ARG B 1 276 ? -16.204 30.289  -36.004  1.00 78.26  ? 276 ARG B CZ    1 
ATOM   6215  N  NH1   . ARG B 1 276 ? -15.797 29.249  -36.714  1.00 77.16  ? 276 ARG B NH1   1 
ATOM   6216  N  NH2   . ARG B 1 276 ? -15.341 30.991  -35.279  1.00 67.39  ? 276 ARG B NH2   1 
ATOM   6217  N  N     . SER B 1 277 ? -22.129 30.410  -32.254  1.00 34.44  ? 277 SER B N     1 
ATOM   6218  C  CA    . SER B 1 277 ? -22.574 31.120  -31.066  1.00 38.52  ? 277 SER B CA    1 
ATOM   6219  C  C     . SER B 1 277 ? -21.756 32.400  -30.874  1.00 37.27  ? 277 SER B C     1 
ATOM   6220  O  O     . SER B 1 277 ? -20.620 32.524  -31.334  1.00 38.00  ? 277 SER B O     1 
ATOM   6221  C  CB    . SER B 1 277 ? -22.511 30.251  -29.837  1.00 34.19  ? 277 SER B CB    1 
ATOM   6222  O  OG    . SER B 1 277 ? -21.162 29.939  -29.525  1.00 39.73  ? 277 SER B OG    1 
ATOM   6223  N  N     . LEU B 1 278 ? -22.369 33.348  -30.179  1.00 40.18  ? 278 LEU B N     1 
ATOM   6224  C  CA    . LEU B 1 278 ? -21.786 34.650  -29.939  1.00 41.64  ? 278 LEU B CA    1 
ATOM   6225  C  C     . LEU B 1 278 ? -20.346 34.509  -29.466  1.00 43.09  ? 278 LEU B C     1 
ATOM   6226  O  O     . LEU B 1 278 ? -19.465 35.176  -30.005  1.00 42.07  ? 278 LEU B O     1 
ATOM   6227  C  CB    . LEU B 1 278 ? -22.610 35.386  -28.885  1.00 45.68  ? 278 LEU B CB    1 
ATOM   6228  C  CG    . LEU B 1 278 ? -21.976 36.671  -28.349  1.00 44.73  ? 278 LEU B CG    1 
ATOM   6229  C  CD1   . LEU B 1 278 ? -21.892 37.716  -29.448  1.00 40.33  ? 278 LEU B CD1   1 
ATOM   6230  C  CD2   . LEU B 1 278 ? -22.758 37.212  -27.149  1.00 48.45  ? 278 LEU B CD2   1 
ATOM   6231  N  N     . VAL B 1 279 ? -20.111 33.650  -28.471  1.00 39.95  ? 279 VAL B N     1 
ATOM   6232  C  CA    . VAL B 1 279 ? -18.819 33.638  -27.806  1.00 40.57  ? 279 VAL B CA    1 
ATOM   6233  C  C     . VAL B 1 279 ? -17.770 33.029  -28.733  1.00 42.64  ? 279 VAL B C     1 
ATOM   6234  O  O     . VAL B 1 279 ? -16.600 33.421  -28.709  1.00 40.56  ? 279 VAL B O     1 
ATOM   6235  C  CB    . VAL B 1 279 ? -18.841 32.944  -26.427  1.00 38.64  ? 279 VAL B CB    1 
ATOM   6236  C  CG1   . VAL B 1 279 ? -17.439 32.795  -25.837  1.00 41.31  ? 279 VAL B CG1   1 
ATOM   6237  C  CG2   . VAL B 1 279 ? -19.737 33.652  -25.435  1.00 40.95  ? 279 VAL B CG2   1 
ATOM   6238  N  N     . LEU B 1 280 ? -18.176 32.061  -29.553  1.00 47.05  ? 280 LEU B N     1 
ATOM   6239  C  CA    . LEU B 1 280 ? -17.215 31.427  -30.435  1.00 44.79  ? 280 LEU B CA    1 
ATOM   6240  C  C     . LEU B 1 280 ? -16.733 32.436  -31.476  1.00 43.32  ? 280 LEU B C     1 
ATOM   6241  O  O     . LEU B 1 280 ? -15.545 32.482  -31.787  1.00 40.93  ? 280 LEU B O     1 
ATOM   6242  C  CB    . LEU B 1 280 ? -17.835 30.193  -31.090  1.00 43.60  ? 280 LEU B CB    1 
ATOM   6243  C  CG    . LEU B 1 280 ? -16.946 29.508  -32.118  1.00 42.14  ? 280 LEU B CG    1 
ATOM   6244  C  CD1   . LEU B 1 280 ? -15.629 29.097  -31.479  1.00 41.51  ? 280 LEU B CD1   1 
ATOM   6245  C  CD2   . LEU B 1 280 ? -17.645 28.290  -32.710  1.00 43.64  ? 280 LEU B CD2   1 
ATOM   6246  N  N     . ASP B 1 281 ? -17.655 33.224  -32.033  1.00 45.38  ? 281 ASP B N     1 
ATOM   6247  C  CA    . ASP B 1 281 ? -17.285 34.258  -33.000  1.00 49.12  ? 281 ASP B CA    1 
ATOM   6248  C  C     . ASP B 1 281 ? -16.555 35.417  -32.324  1.00 41.92  ? 281 ASP B C     1 
ATOM   6249  O  O     . ASP B 1 281 ? -15.541 35.870  -32.830  1.00 41.95  ? 281 ASP B O     1 
ATOM   6250  C  CB    . ASP B 1 281 ? -18.494 34.749  -33.788  1.00 50.17  ? 281 ASP B CB    1 
ATOM   6251  C  CG    . ASP B 1 281 ? -18.861 33.770  -34.887  1.00 56.36  ? 281 ASP B CG    1 
ATOM   6252  O  OD1   . ASP B 1 281 ? -17.983 32.949  -35.249  1.00 55.40  ? 281 ASP B OD1   1 
ATOM   6253  O  OD2   . ASP B 1 281 ? -20.020 33.809  -35.348  1.00 59.96  ? 281 ASP B OD2   1 
ATOM   6254  N  N     . ALA B 1 282 ? -17.004 35.820  -31.135  1.00 39.53  ? 282 ALA B N     1 
ATOM   6255  C  CA    . ALA B 1 282 ? -16.350 36.915  -30.446  1.00 40.25  ? 282 ALA B CA    1 
ATOM   6256  C  C     . ALA B 1 282 ? -14.908 36.533  -30.113  1.00 44.07  ? 282 ALA B C     1 
ATOM   6257  O  O     . ALA B 1 282 ? -14.018 37.385  -30.192  1.00 41.81  ? 282 ALA B O     1 
ATOM   6258  C  CB    . ALA B 1 282 ? -17.129 37.305  -29.224  1.00 38.50  ? 282 ALA B CB    1 
ATOM   6259  N  N     . ALA B 1 283 ? -14.684 35.257  -29.741  1.00 38.65  ? 283 ALA B N     1 
ATOM   6260  C  CA    . ALA B 1 283 ? -13.373 34.811  -29.311  1.00 36.85  ? 283 ALA B CA    1 
ATOM   6261  C  C     . ALA B 1 283 ? -12.370 34.891  -30.457  1.00 36.82  ? 283 ALA B C     1 
ATOM   6262  O  O     . ALA B 1 283 ? -11.187 34.697  -30.230  1.00 37.26  ? 283 ALA B O     1 
ATOM   6263  C  CB    . ALA B 1 283 ? -13.430 33.421  -28.740  1.00 35.87  ? 283 ALA B CB    1 
ATOM   6264  N  N     . ILE B 1 284 ? -12.843 35.117  -31.689  1.00 41.18  ? 284 ILE B N     1 
ATOM   6265  C  CA    . ILE B 1 284 ? -11.911 35.280  -32.790  1.00 45.32  ? 284 ILE B CA    1 
ATOM   6266  C  C     . ILE B 1 284 ? -11.203 36.635  -32.669  1.00 45.07  ? 284 ILE B C     1 
ATOM   6267  O  O     . ILE B 1 284 ? -10.032 36.735  -33.022  1.00 45.81  ? 284 ILE B O     1 
ATOM   6268  C  CB    . ILE B 1 284 ? -12.585 35.066  -34.162  1.00 48.08  ? 284 ILE B CB    1 
ATOM   6269  C  CG1   . ILE B 1 284 ? -13.173 33.661  -34.315  1.00 45.85  ? 284 ILE B CG1   1 
ATOM   6270  C  CG2   . ILE B 1 284 ? -11.587 35.343  -35.272  1.00 49.08  ? 284 ILE B CG2   1 
ATOM   6271  C  CD1   . ILE B 1 284 ? -12.172 32.543  -34.080  1.00 45.74  ? 284 ILE B CD1   1 
ATOM   6272  N  N     . THR B 1 285 ? -11.857 37.656  -32.106  1.00 45.73  ? 285 THR B N     1 
ATOM   6273  C  CA    . THR B 1 285 ? -11.233 38.974  -32.050  1.00 44.15  ? 285 THR B CA    1 
ATOM   6274  C  C     . THR B 1 285 ? -11.189 39.595  -30.650  1.00 45.16  ? 285 THR B C     1 
ATOM   6275  O  O     . THR B 1 285 ? -10.659 40.700  -30.522  1.00 44.11  ? 285 THR B O     1 
ATOM   6276  C  CB    . THR B 1 285 ? -11.925 39.935  -33.029  1.00 43.34  ? 285 THR B CB    1 
ATOM   6277  O  OG1   . THR B 1 285 ? -13.245 40.227  -32.561  1.00 42.48  ? 285 THR B OG1   1 
ATOM   6278  C  CG2   . THR B 1 285 ? -11.961 39.396  -34.447  1.00 42.56  ? 285 THR B CG2   1 
ATOM   6279  N  N     . ARG B 1 286 ? -11.739 38.921  -29.625  1.00 41.63  ? 286 ARG B N     1 
ATOM   6280  C  CA    . ARG B 1 286 ? -11.806 39.440  -28.266  1.00 41.91  ? 286 ARG B CA    1 
ATOM   6281  C  C     . ARG B 1 286 ? -11.554 38.309  -27.272  1.00 42.40  ? 286 ARG B C     1 
ATOM   6282  O  O     . ARG B 1 286 ? -11.641 37.137  -27.653  1.00 43.39  ? 286 ARG B O     1 
ATOM   6283  C  CB    . ARG B 1 286 ? -13.150 40.112  -27.977  1.00 43.29  ? 286 ARG B CB    1 
ATOM   6284  C  CG    . ARG B 1 286 ? -13.488 41.286  -28.889  1.00 43.40  ? 286 ARG B CG    1 
ATOM   6285  C  CD    . ARG B 1 286 ? -12.654 42.549  -28.666  1.00 43.70  ? 286 ARG B CD    1 
ATOM   6286  N  NE    . ARG B 1 286 ? -13.058 43.647  -29.543  1.00 40.14  ? 286 ARG B NE    1 
ATOM   6287  C  CZ    . ARG B 1 286 ? -12.778 43.754  -30.836  1.00 40.13  ? 286 ARG B CZ    1 
ATOM   6288  N  NH1   . ARG B 1 286 ? -11.935 42.928  -31.432  1.00 40.10  ? 286 ARG B NH1   1 
ATOM   6289  N  NH2   . ARG B 1 286 ? -13.315 44.738  -31.532  1.00 45.49  ? 286 ARG B NH2   1 
ATOM   6290  N  N     . THR B 1 287 ? -11.192 38.675  -26.023  1.00 42.65  ? 287 THR B N     1 
ATOM   6291  C  CA    . THR B 1 287 ? -10.989 37.703  -24.955  1.00 41.03  ? 287 THR B CA    1 
ATOM   6292  C  C     . THR B 1 287 ? -12.017 37.950  -23.858  1.00 41.95  ? 287 THR B C     1 
ATOM   6293  O  O     . THR B 1 287 ? -12.640 39.004  -23.810  1.00 42.46  ? 287 THR B O     1 
ATOM   6294  C  CB    . THR B 1 287 ? -9.582  37.701  -24.347  1.00 41.87  ? 287 THR B CB    1 
ATOM   6295  O  OG1   . THR B 1 287 ? -9.435  38.925  -23.627  1.00 44.04  ? 287 THR B OG1   1 
ATOM   6296  C  CG2   . THR B 1 287 ? -8.473  37.496  -25.354  1.00 40.43  ? 287 THR B CG2   1 
ATOM   6297  N  N     . LYS B 1 288 ? -12.205 36.951  -22.989  1.00 41.82  ? 288 LYS B N     1 
ATOM   6298  C  CA    . LYS B 1 288 ? -13.204 37.055  -21.935  1.00 44.10  ? 288 LYS B CA    1 
ATOM   6299  C  C     . LYS B 1 288 ? -12.842 38.198  -20.980  1.00 40.54  ? 288 LYS B C     1 
ATOM   6300  O  O     . LYS B 1 288 ? -13.723 38.954  -20.603  1.00 35.77  ? 288 LYS B O     1 
ATOM   6301  C  CB    . LYS B 1 288 ? -13.363 35.774  -21.101  1.00 43.85  ? 288 LYS B CB    1 
ATOM   6302  C  CG    . LYS B 1 288 ? -14.317 35.952  -19.918  1.00 45.16  ? 288 LYS B CG    1 
ATOM   6303  C  CD    . LYS B 1 288 ? -14.835 34.715  -19.233  1.00 48.37  ? 288 LYS B CD    1 
ATOM   6304  C  CE    . LYS B 1 288 ? -13.982 34.221  -18.094  1.00 54.79  ? 288 LYS B CE    1 
ATOM   6305  N  NZ    . LYS B 1 288 ? -14.820 33.576  -17.052  1.00 51.87  ? 288 LYS B NZ    1 
ATOM   6306  N  N     . SER B 1 289 ? -11.557 38.308  -20.600  1.00 39.89  ? 289 SER B N     1 
ATOM   6307  C  CA    . SER B 1 289 ? -11.110 39.285  -19.614  1.00 42.27  ? 289 SER B CA    1 
ATOM   6308  C  C     . SER B 1 289 ? -11.295 40.723  -20.111  1.00 41.11  ? 289 SER B C     1 
ATOM   6309  O  O     . SER B 1 289 ? -11.277 41.661  -19.329  1.00 44.95  ? 289 SER B O     1 
ATOM   6310  C  CB    . SER B 1 289 ? -9.687  39.023  -19.212  1.00 42.96  ? 289 SER B CB    1 
ATOM   6311  O  OG    . SER B 1 289 ? -8.832  39.211  -20.326  1.00 44.82  ? 289 SER B OG    1 
ATOM   6312  N  N     . GLN B 1 290 ? -11.566 40.899  -21.400  1.00 39.41  ? 290 GLN B N     1 
ATOM   6313  C  CA    . GLN B 1 290 ? -11.864 42.206  -21.948  1.00 39.01  ? 290 GLN B CA    1 
ATOM   6314  C  C     . GLN B 1 290 ? -13.313 42.625  -21.730  1.00 40.49  ? 290 GLN B C     1 
ATOM   6315  O  O     . GLN B 1 290 ? -13.652 43.776  -21.971  1.00 37.95  ? 290 GLN B O     1 
ATOM   6316  C  CB    . GLN B 1 290 ? -11.504 42.195  -23.426  1.00 34.37  ? 290 GLN B CB    1 
ATOM   6317  C  CG    . GLN B 1 290 ? -9.991  42.105  -23.578  1.00 37.35  ? 290 GLN B CG    1 
ATOM   6318  C  CD    . GLN B 1 290 ? -9.603  41.903  -25.011  1.00 40.63  ? 290 GLN B CD    1 
ATOM   6319  O  OE1   . GLN B 1 290 ? -10.449 41.692  -25.881  1.00 43.25  ? 290 GLN B OE1   1 
ATOM   6320  N  NE2   . GLN B 1 290 ? -8.307  41.938  -25.246  1.00 48.06  ? 290 GLN B NE2   1 
ATOM   6321  N  N     . TYR B 1 291 ? -14.177 41.706  -21.306  1.00 41.25  ? 291 TYR B N     1 
ATOM   6322  C  CA    . TYR B 1 291 ? -15.606 41.999  -21.293  1.00 38.50  ? 291 TYR B CA    1 
ATOM   6323  C  C     . TYR B 1 291 ? -16.226 41.636  -19.947  1.00 37.30  ? 291 TYR B C     1 
ATOM   6324  O  O     . TYR B 1 291 ? -17.325 42.090  -19.623  1.00 42.61  ? 291 TYR B O     1 
ATOM   6325  C  CB    . TYR B 1 291 ? -16.282 41.275  -22.464  1.00 41.65  ? 291 TYR B CB    1 
ATOM   6326  C  CG    . TYR B 1 291 ? -16.446 42.094  -23.723  1.00 41.13  ? 291 TYR B CG    1 
ATOM   6327  C  CD1   . TYR B 1 291 ? -17.376 43.124  -23.781  1.00 38.36  ? 291 TYR B CD1   1 
ATOM   6328  C  CD2   . TYR B 1 291 ? -15.699 41.834  -24.860  1.00 47.22  ? 291 TYR B CD2   1 
ATOM   6329  C  CE1   . TYR B 1 291 ? -17.565 43.867  -24.931  1.00 43.28  ? 291 TYR B CE1   1 
ATOM   6330  C  CE2   . TYR B 1 291 ? -15.854 42.591  -26.014  1.00 47.76  ? 291 TYR B CE2   1 
ATOM   6331  C  CZ    . TYR B 1 291 ? -16.791 43.606  -26.050  1.00 43.57  ? 291 TYR B CZ    1 
ATOM   6332  O  OH    . TYR B 1 291 ? -16.942 44.355  -27.171  1.00 49.05  ? 291 TYR B OH    1 
ATOM   6333  N  N     . TYR B 1 292 ? -15.549 40.778  -19.186  1.00 43.07  ? 292 TYR B N     1 
ATOM   6334  C  CA    . TYR B 1 292 ? -16.100 40.235  -17.956  1.00 46.78  ? 292 TYR B CA    1 
ATOM   6335  C  C     . TYR B 1 292 ? -14.967 39.797  -17.042  1.00 52.13  ? 292 TYR B C     1 
ATOM   6336  O  O     . TYR B 1 292 ? -14.053 39.110  -17.486  1.00 53.03  ? 292 TYR B O     1 
ATOM   6337  C  CB    . TYR B 1 292 ? -16.999 39.021  -18.209  1.00 49.12  ? 292 TYR B CB    1 
ATOM   6338  C  CG    . TYR B 1 292 ? -17.688 38.473  -16.978  1.00 44.98  ? 292 TYR B CG    1 
ATOM   6339  C  CD1   . TYR B 1 292 ? -18.522 39.279  -16.216  1.00 51.40  ? 292 TYR B CD1   1 
ATOM   6340  C  CD2   . TYR B 1 292 ? -17.508 37.164  -16.570  1.00 46.47  ? 292 TYR B CD2   1 
ATOM   6341  C  CE1   . TYR B 1 292 ? -19.174 38.804  -15.091  1.00 48.94  ? 292 TYR B CE1   1 
ATOM   6342  C  CE2   . TYR B 1 292 ? -18.146 36.669  -15.442  1.00 48.85  ? 292 TYR B CE2   1 
ATOM   6343  C  CZ    . TYR B 1 292 ? -18.993 37.489  -14.713  1.00 51.06  ? 292 TYR B CZ    1 
ATOM   6344  O  OH    . TYR B 1 292 ? -19.645 37.053  -13.593  1.00 51.26  ? 292 TYR B OH    1 
ATOM   6345  N  N     . ASP B 1 293 ? -15.123 40.136  -15.755  1.00 59.70  ? 293 ASP B N     1 
ATOM   6346  C  CA    . ASP B 1 293 ? -14.093 39.998  -14.744  1.00 64.54  ? 293 ASP B CA    1 
ATOM   6347  C  C     . ASP B 1 293 ? -14.309 38.748  -13.887  1.00 59.91  ? 293 ASP B C     1 
ATOM   6348  O  O     . ASP B 1 293 ? -13.399 38.330  -13.181  1.00 59.99  ? 293 ASP B O     1 
ATOM   6349  C  CB    . ASP B 1 293 ? -14.092 41.254  -13.871  1.00 72.57  ? 293 ASP B CB    1 
ATOM   6350  C  CG    . ASP B 1 293 ? -12.731 41.565  -13.289  1.00 86.23  ? 293 ASP B CG    1 
ATOM   6351  O  OD1   . ASP B 1 293 ? -11.889 40.638  -13.238  1.00 94.61  ? 293 ASP B OD1   1 
ATOM   6352  O  OD2   . ASP B 1 293 ? -12.513 42.738  -12.932  1.00 100.39 ? 293 ASP B OD2   1 
ATOM   6353  N  N     . GLY B 1 294 ? -15.504 38.147  -13.946  1.00 56.10  ? 294 GLY B N     1 
ATOM   6354  C  CA    . GLY B 1 294 ? -15.839 37.007  -13.103  1.00 47.88  ? 294 GLY B CA    1 
ATOM   6355  C  C     . GLY B 1 294 ? -15.113 35.732  -13.517  1.00 52.38  ? 294 GLY B C     1 
ATOM   6356  O  O     . GLY B 1 294 ? -14.688 35.584  -14.661  1.00 51.58  ? 294 GLY B O     1 
ATOM   6357  N  N     . ASP B 1 295 ? -15.000 34.796  -12.568  1.00 57.48  ? 295 ASP B N     1 
ATOM   6358  C  CA    . ASP B 1 295 ? -14.473 33.468  -12.843  1.00 58.89  ? 295 ASP B CA    1 
ATOM   6359  C  C     . ASP B 1 295 ? -15.453 32.650  -13.684  1.00 58.98  ? 295 ASP B C     1 
ATOM   6360  O  O     . ASP B 1 295 ? -15.020 31.784  -14.444  1.00 61.80  ? 295 ASP B O     1 
ATOM   6361  C  CB    . ASP B 1 295 ? -14.209 32.669  -11.563  1.00 67.28  ? 295 ASP B CB    1 
ATOM   6362  C  CG    . ASP B 1 295 ? -12.924 33.019  -10.835  1.00 76.91  ? 295 ASP B CG    1 
ATOM   6363  O  OD1   . ASP B 1 295 ? -11.845 32.925  -11.452  1.00 83.20  ? 295 ASP B OD1   1 
ATOM   6364  O  OD2   . ASP B 1 295 ? -13.013 33.342  -9.646   1.00 80.35  ? 295 ASP B OD2   1 
ATOM   6365  N  N     . GLY B 1 296 ? -16.765 32.856  -13.492  1.00 53.28  ? 296 GLY B N     1 
ATOM   6366  C  CA    . GLY B 1 296 ? -17.764 32.028  -14.160  1.00 54.78  ? 296 GLY B CA    1 
ATOM   6367  C  C     . GLY B 1 296 ? -17.941 32.378  -15.641  1.00 52.61  ? 296 GLY B C     1 
ATOM   6368  O  O     . GLY B 1 296 ? -17.258 33.223  -16.205  1.00 46.15  ? 296 GLY B O     1 
ATOM   6369  N  N     . PRO B 1 297 ? -18.937 31.805  -16.331  1.00 51.77  ? 297 PRO B N     1 
ATOM   6370  C  CA    . PRO B 1 297 ? -19.203 32.182  -17.722  1.00 46.31  ? 297 PRO B CA    1 
ATOM   6371  C  C     . PRO B 1 297 ? -19.902 33.533  -17.793  1.00 46.49  ? 297 PRO B C     1 
ATOM   6372  O  O     . PRO B 1 297 ? -20.398 34.026  -16.775  1.00 46.20  ? 297 PRO B O     1 
ATOM   6373  C  CB    . PRO B 1 297 ? -20.120 31.041  -18.175  1.00 48.29  ? 297 PRO B CB    1 
ATOM   6374  C  CG    . PRO B 1 297 ? -20.883 30.685  -16.925  1.00 46.92  ? 297 PRO B CG    1 
ATOM   6375  C  CD    . PRO B 1 297 ? -19.870 30.806  -15.806  1.00 45.85  ? 297 PRO B CD    1 
ATOM   6376  N  N     . ILE B 1 298 ? -19.976 34.120  -18.997  1.00 47.10  ? 298 ILE B N     1 
ATOM   6377  C  CA    . ILE B 1 298 ? -20.461 35.489  -19.125  1.00 46.74  ? 298 ILE B CA    1 
ATOM   6378  C  C     . ILE B 1 298 ? -21.972 35.535  -18.899  1.00 45.86  ? 298 ILE B C     1 
ATOM   6379  O  O     . ILE B 1 298 ? -22.750 34.724  -19.385  1.00 43.73  ? 298 ILE B O     1 
ATOM   6380  C  CB    . ILE B 1 298 ? -20.053 36.167  -20.451  1.00 47.48  ? 298 ILE B CB    1 
ATOM   6381  C  CG1   . ILE B 1 298 ? -20.790 35.584  -21.657  1.00 48.29  ? 298 ILE B CG1   1 
ATOM   6382  C  CG2   . ILE B 1 298 ? -18.533 36.133  -20.627  1.00 50.93  ? 298 ILE B CG2   1 
ATOM   6383  C  CD1   . ILE B 1 298 ? -20.555 36.304  -22.954  1.00 47.60  ? 298 ILE B CD1   1 
ATOM   6384  N  N     . PRO B 1 299 ? -22.460 36.554  -18.183  1.00 45.47  ? 299 PRO B N     1 
ATOM   6385  C  CA    . PRO B 1 299 ? -23.891 36.709  -17.995  1.00 43.31  ? 299 PRO B CA    1 
ATOM   6386  C  C     . PRO B 1 299 ? -24.501 37.420  -19.194  1.00 44.48  ? 299 PRO B C     1 
ATOM   6387  O  O     . PRO B 1 299 ? -23.796 38.006  -20.017  1.00 46.76  ? 299 PRO B O     1 
ATOM   6388  C  CB    . PRO B 1 299 ? -23.932 37.552  -16.711  1.00 45.36  ? 299 PRO B CB    1 
ATOM   6389  C  CG    . PRO B 1 299 ? -22.739 38.480  -16.877  1.00 47.24  ? 299 PRO B CG    1 
ATOM   6390  C  CD    . PRO B 1 299 ? -21.677 37.621  -17.544  1.00 47.83  ? 299 PRO B CD    1 
ATOM   6391  N  N     . PRO B 1 300 ? -25.840 37.345  -19.317  1.00 45.51  ? 300 PRO B N     1 
ATOM   6392  C  CA    . PRO B 1 300 ? -26.588 37.960  -20.410  1.00 46.24  ? 300 PRO B CA    1 
ATOM   6393  C  C     . PRO B 1 300 ? -26.313 39.430  -20.724  1.00 46.20  ? 300 PRO B C     1 
ATOM   6394  O  O     . PRO B 1 300 ? -26.286 39.811  -21.879  1.00 43.64  ? 300 PRO B O     1 
ATOM   6395  C  CB    . PRO B 1 300 ? -28.040 37.795  -19.919  1.00 45.73  ? 300 PRO B CB    1 
ATOM   6396  C  CG    . PRO B 1 300 ? -28.018 36.488  -19.185  1.00 46.29  ? 300 PRO B CG    1 
ATOM   6397  C  CD    . PRO B 1 300 ? -26.697 36.516  -18.447  1.00 51.87  ? 300 PRO B CD    1 
ATOM   6398  N  N     . SER B 1 301 ? -26.124 40.259  -19.699  1.00 48.01  ? 301 SER B N     1 
ATOM   6399  C  CA    . SER B 1 301 ? -25.816 41.662  -19.934  1.00 45.48  ? 301 SER B CA    1 
ATOM   6400  C  C     . SER B 1 301 ? -24.480 41.790  -20.672  1.00 39.15  ? 301 SER B C     1 
ATOM   6401  O  O     . SER B 1 301 ? -24.300 42.665  -21.499  1.00 45.11  ? 301 SER B O     1 
ATOM   6402  C  CB    . SER B 1 301 ? -25.813 42.425  -18.630  1.00 38.18  ? 301 SER B CB    1 
ATOM   6403  O  OG    . SER B 1 301 ? -24.857 41.842  -17.759  1.00 41.04  ? 301 SER B OG    1 
ATOM   6404  N  N     . VAL B 1 302 ? -23.517 40.927  -20.396  1.00 37.39  ? 302 VAL B N     1 
ATOM   6405  C  CA    . VAL B 1 302 ? -22.242 41.043  -21.092  1.00 42.23  ? 302 VAL B CA    1 
ATOM   6406  C  C     . VAL B 1 302 ? -22.394 40.592  -22.540  1.00 45.94  ? 302 VAL B C     1 
ATOM   6407  O  O     . VAL B 1 302 ? -21.764 41.175  -23.430  1.00 41.86  ? 302 VAL B O     1 
ATOM   6408  C  CB    . VAL B 1 302 ? -21.122 40.268  -20.384  1.00 43.68  ? 302 VAL B CB    1 
ATOM   6409  C  CG1   . VAL B 1 302 ? -19.864 40.182  -21.228  1.00 47.21  ? 302 VAL B CG1   1 
ATOM   6410  C  CG2   . VAL B 1 302 ? -20.835 40.877  -19.032  1.00 44.70  ? 302 VAL B CG2   1 
ATOM   6411  N  N     . ALA B 1 303 ? -23.259 39.584  -22.756  1.00 45.76  ? 303 ALA B N     1 
ATOM   6412  C  CA    . ALA B 1 303 ? -23.532 39.087  -24.091  1.00 44.69  ? 303 ALA B CA    1 
ATOM   6413  C  C     . ALA B 1 303 ? -24.096 40.223  -24.940  1.00 43.18  ? 303 ALA B C     1 
ATOM   6414  O  O     . ALA B 1 303 ? -23.619 40.467  -26.046  1.00 42.82  ? 303 ALA B O     1 
ATOM   6415  C  CB    . ALA B 1 303 ? -24.479 37.897  -24.052  1.00 46.09  ? 303 ALA B CB    1 
ATOM   6416  N  N     . LYS B 1 304 ? -25.111 40.911  -24.419  1.00 38.32  ? 304 LYS B N     1 
ATOM   6417  C  CA    . LYS B 1 304 ? -25.709 42.033  -25.135  1.00 45.58  ? 304 LYS B CA    1 
ATOM   6418  C  C     . LYS B 1 304 ? -24.675 43.095  -25.529  1.00 42.14  ? 304 LYS B C     1 
ATOM   6419  O  O     . LYS B 1 304 ? -24.750 43.671  -26.620  1.00 42.34  ? 304 LYS B O     1 
ATOM   6420  C  CB    . LYS B 1 304 ? -26.811 42.655  -24.279  1.00 49.85  ? 304 LYS B CB    1 
ATOM   6421  C  CG    . LYS B 1 304 ? -28.048 41.776  -24.116  1.00 57.02  ? 304 LYS B CG    1 
ATOM   6422  C  CD    . LYS B 1 304 ? -28.726 41.910  -22.762  1.00 69.92  ? 304 LYS B CD    1 
ATOM   6423  C  CE    . LYS B 1 304 ? -29.886 42.881  -22.721  1.00 77.94  ? 304 LYS B CE    1 
ATOM   6424  N  NZ    . LYS B 1 304 ? -31.179 42.176  -22.863  1.00 73.64  ? 304 LYS B NZ    1 
ATOM   6425  N  N     . THR B 1 305 ? -23.741 43.384  -24.625  1.00 42.38  ? 305 THR B N     1 
ATOM   6426  C  CA    . THR B 1 305 ? -22.725 44.389  -24.871  1.00 45.06  ? 305 THR B CA    1 
ATOM   6427  C  C     . THR B 1 305 ? -21.786 43.933  -25.983  1.00 44.79  ? 305 THR B C     1 
ATOM   6428  O  O     . THR B 1 305 ? -21.414 44.737  -26.826  1.00 43.00  ? 305 THR B O     1 
ATOM   6429  C  CB    . THR B 1 305 ? -21.946 44.700  -23.589  1.00 46.41  ? 305 THR B CB    1 
ATOM   6430  O  OG1   . THR B 1 305 ? -22.886 45.197  -22.644  1.00 48.02  ? 305 THR B OG1   1 
ATOM   6431  C  CG2   . THR B 1 305 ? -20.868 45.739  -23.780  1.00 49.11  ? 305 THR B CG2   1 
ATOM   6432  N  N     . MET B 1 306 ? -21.416 42.643  -25.983  1.00 43.30  ? 306 MET B N     1 
ATOM   6433  C  CA    . MET B 1 306 ? -20.510 42.106  -26.984  1.00 44.66  ? 306 MET B CA    1 
ATOM   6434  C  C     . MET B 1 306 ? -21.164 42.164  -28.363  1.00 40.67  ? 306 MET B C     1 
ATOM   6435  O  O     . MET B 1 306 ? -20.536 42.555  -29.348  1.00 40.30  ? 306 MET B O     1 
ATOM   6436  C  CB    . MET B 1 306 ? -20.153 40.662  -26.646  1.00 47.57  ? 306 MET B CB    1 
ATOM   6437  C  CG    . MET B 1 306 ? -19.219 40.556  -25.480  1.00 48.67  ? 306 MET B CG    1 
ATOM   6438  S  SD    . MET B 1 306 ? -19.099 38.837  -24.981  1.00 53.61  ? 306 MET B SD    1 
ATOM   6439  C  CE    . MET B 1 306 ? -17.849 38.300  -26.134  1.00 56.39  ? 306 MET B CE    1 
ATOM   6440  N  N     . MET B 1 307 ? -22.448 41.805  -28.396  1.00 37.20  ? 307 MET B N     1 
ATOM   6441  C  CA    . MET B 1 307 ? -23.276 41.873  -29.587  1.00 40.24  ? 307 MET B CA    1 
ATOM   6442  C  C     . MET B 1 307 ? -23.339 43.298  -30.163  1.00 44.52  ? 307 MET B C     1 
ATOM   6443  O  O     . MET B 1 307 ? -23.218 43.475  -31.373  1.00 42.05  ? 307 MET B O     1 
ATOM   6444  C  CB    . MET B 1 307 ? -24.690 41.406  -29.249  1.00 38.11  ? 307 MET B CB    1 
ATOM   6445  C  CG    . MET B 1 307 ? -24.813 39.899  -29.027  1.00 39.84  ? 307 MET B CG    1 
ATOM   6446  S  SD    . MET B 1 307 ? -26.393 39.472  -28.245  1.00 46.96  ? 307 MET B SD    1 
ATOM   6447  C  CE    . MET B 1 307 ? -27.552 39.908  -29.537  1.00 46.37  ? 307 MET B CE    1 
ATOM   6448  N  N     . ALA B 1 308 ? -23.547 44.307  -29.306  1.00 49.27  ? 308 ALA B N     1 
ATOM   6449  C  CA    . ALA B 1 308 ? -23.653 45.705  -29.732  1.00 47.58  ? 308 ALA B CA    1 
ATOM   6450  C  C     . ALA B 1 308 ? -22.319 46.205  -30.283  1.00 43.21  ? 308 ALA B C     1 
ATOM   6451  O  O     . ALA B 1 308 ? -22.249 46.815  -31.347  1.00 45.52  ? 308 ALA B O     1 
ATOM   6452  C  CB    . ALA B 1 308 ? -24.119 46.545  -28.571  1.00 46.75  ? 308 ALA B CB    1 
ATOM   6453  N  N     . ASP B 1 309 ? -21.238 45.895  -29.573  1.00 44.89  ? 309 ASP B N     1 
ATOM   6454  C  CA    . ASP B 1 309 ? -19.917 46.363  -29.950  1.00 47.09  ? 309 ASP B CA    1 
ATOM   6455  C  C     . ASP B 1 309 ? -19.444 45.760  -31.277  1.00 48.29  ? 309 ASP B C     1 
ATOM   6456  O  O     . ASP B 1 309 ? -18.831 46.465  -32.071  1.00 47.36  ? 309 ASP B O     1 
ATOM   6457  C  CB    . ASP B 1 309 ? -18.902 45.991  -28.870  1.00 48.89  ? 309 ASP B CB    1 
ATOM   6458  C  CG    . ASP B 1 309 ? -19.045 46.771  -27.573  1.00 54.28  ? 309 ASP B CG    1 
ATOM   6459  O  OD1   . ASP B 1 309 ? -19.968 47.649  -27.473  1.00 50.71  ? 309 ASP B OD1   1 
ATOM   6460  O  OD2   . ASP B 1 309 ? -18.223 46.509  -26.681  1.00 48.68  ? 309 ASP B OD2   1 
ATOM   6461  N  N     . LEU B 1 310 ? -19.643 44.441  -31.470  1.00 39.78  ? 310 LEU B N     1 
ATOM   6462  C  CA    . LEU B 1 310 ? -18.975 43.697  -32.529  1.00 43.34  ? 310 LEU B CA    1 
ATOM   6463  C  C     . LEU B 1 310 ? -19.867 43.462  -33.755  1.00 44.07  ? 310 LEU B C     1 
ATOM   6464  O  O     . LEU B 1 310 ? -19.376 42.929  -34.752  1.00 41.63  ? 310 LEU B O     1 
ATOM   6465  C  CB    . LEU B 1 310 ? -18.541 42.347  -31.958  1.00 45.02  ? 310 LEU B CB    1 
ATOM   6466  C  CG    . LEU B 1 310 ? -17.623 42.393  -30.745  1.00 46.65  ? 310 LEU B CG    1 
ATOM   6467  C  CD1   . LEU B 1 310 ? -17.381 40.981  -30.234  1.00 40.99  ? 310 LEU B CD1   1 
ATOM   6468  C  CD2   . LEU B 1 310 ? -16.309 43.081  -31.100  1.00 49.68  ? 310 LEU B CD2   1 
ATOM   6469  N  N     . ASP B 1 311 ? -21.150 43.856  -33.672  1.00 45.20  ? 311 ASP B N     1 
ATOM   6470  C  CA    . ASP B 1 311 ? -22.167 43.606  -34.693  1.00 41.27  ? 311 ASP B CA    1 
ATOM   6471  C  C     . ASP B 1 311 ? -22.278 42.099  -34.943  1.00 39.53  ? 311 ASP B C     1 
ATOM   6472  O  O     . ASP B 1 311 ? -22.179 41.632  -36.082  1.00 41.80  ? 311 ASP B O     1 
ATOM   6473  C  CB    . ASP B 1 311 ? -21.932 44.434  -35.963  1.00 40.48  ? 311 ASP B CB    1 
ATOM   6474  C  CG    . ASP B 1 311 ? -21.923 45.951  -35.752  1.00 47.14  ? 311 ASP B CG    1 
ATOM   6475  O  OD1   . ASP B 1 311 ? -22.280 46.388  -34.659  1.00 43.31  ? 311 ASP B OD1   1 
ATOM   6476  O  OD2   . ASP B 1 311 ? -21.487 46.688  -36.667  1.00 44.49  ? 311 ASP B OD2   1 
ATOM   6477  N  N     . LEU B 1 312 ? -22.453 41.351  -33.843  1.00 40.24  ? 312 LEU B N     1 
ATOM   6478  C  CA    . LEU B 1 312 ? -22.710 39.920  -33.872  1.00 42.03  ? 312 LEU B CA    1 
ATOM   6479  C  C     . LEU B 1 312 ? -24.046 39.672  -33.188  1.00 43.19  ? 312 LEU B C     1 
ATOM   6480  O  O     . LEU B 1 312 ? -24.453 40.455  -32.329  1.00 46.77  ? 312 LEU B O     1 
ATOM   6481  C  CB    . LEU B 1 312 ? -21.604 39.154  -33.142  1.00 39.73  ? 312 LEU B CB    1 
ATOM   6482  C  CG    . LEU B 1 312 ? -20.206 39.245  -33.746  1.00 39.38  ? 312 LEU B CG    1 
ATOM   6483  C  CD1   . LEU B 1 312 ? -19.184 38.560  -32.857  1.00 41.04  ? 312 LEU B CD1   1 
ATOM   6484  C  CD2   . LEU B 1 312 ? -20.166 38.645  -35.140  1.00 42.26  ? 312 LEU B CD2   1 
ATOM   6485  N  N     . GLY B 1 313 ? -24.698 38.569  -33.562  1.00 42.26  ? 313 GLY B N     1 
ATOM   6486  C  CA    . GLY B 1 313 ? -25.871 38.097  -32.847  1.00 41.95  ? 313 GLY B CA    1 
ATOM   6487  C  C     . GLY B 1 313 ? -25.497 37.016  -31.844  1.00 39.18  ? 313 GLY B C     1 
ATOM   6488  O  O     . GLY B 1 313 ? -24.325 36.694  -31.656  1.00 40.78  ? 313 GLY B O     1 
ATOM   6489  N  N     . MET B 1 314 ? -26.522 36.433  -31.230  1.00 43.22  ? 314 MET B N     1 
ATOM   6490  C  CA    . MET B 1 314 ? -26.358 35.237  -30.416  1.00 41.17  ? 314 MET B CA    1 
ATOM   6491  C  C     . MET B 1 314 ? -26.022 34.049  -31.316  1.00 36.04  ? 314 MET B C     1 
ATOM   6492  O  O     . MET B 1 314 ? -25.323 33.156  -30.877  1.00 38.33  ? 314 MET B O     1 
ATOM   6493  C  CB    . MET B 1 314 ? -27.630 34.956  -29.614  1.00 42.56  ? 314 MET B CB    1 
ATOM   6494  C  CG    . MET B 1 314 ? -27.766 35.864  -28.412  1.00 46.78  ? 314 MET B CG    1 
ATOM   6495  S  SD    . MET B 1 314 ? -26.460 35.607  -27.170  1.00 49.66  ? 314 MET B SD    1 
ATOM   6496  C  CE    . MET B 1 314 ? -26.845 33.958  -26.575  1.00 50.29  ? 314 MET B CE    1 
ATOM   6497  N  N     . TRP B 1 315 ? -26.500 34.090  -32.573  1.00 38.43  ? 315 TRP B N     1 
ATOM   6498  C  CA    . TRP B 1 315 ? -26.158 33.134  -33.626  1.00 42.65  ? 315 TRP B CA    1 
ATOM   6499  C  C     . TRP B 1 315 ? -25.693 33.888  -34.864  1.00 38.33  ? 315 TRP B C     1 
ATOM   6500  O  O     . TRP B 1 315 ? -26.327 34.855  -35.250  1.00 38.84  ? 315 TRP B O     1 
ATOM   6501  C  CB    . TRP B 1 315 ? -27.353 32.238  -33.998  1.00 39.93  ? 315 TRP B CB    1 
ATOM   6502  C  CG    . TRP B 1 315 ? -27.787 31.400  -32.853  1.00 35.59  ? 315 TRP B CG    1 
ATOM   6503  C  CD1   . TRP B 1 315 ? -28.868 31.585  -32.047  1.00 39.66  ? 315 TRP B CD1   1 
ATOM   6504  C  CD2   . TRP B 1 315 ? -27.069 30.291  -32.316  1.00 37.68  ? 315 TRP B CD2   1 
ATOM   6505  N  NE1   . TRP B 1 315 ? -28.865 30.658  -31.041  1.00 37.58  ? 315 TRP B NE1   1 
ATOM   6506  C  CE2   . TRP B 1 315 ? -27.796 29.832  -31.201  1.00 38.48  ? 315 TRP B CE2   1 
ATOM   6507  C  CE3   . TRP B 1 315 ? -25.904 29.629  -32.687  1.00 37.92  ? 315 TRP B CE3   1 
ATOM   6508  C  CZ2   . TRP B 1 315 ? -27.398 28.728  -30.459  1.00 40.07  ? 315 TRP B CZ2   1 
ATOM   6509  C  CZ3   . TRP B 1 315 ? -25.490 28.559  -31.935  1.00 35.05  ? 315 TRP B CZ3   1 
ATOM   6510  C  CH2   . TRP B 1 315 ? -26.239 28.102  -30.853  1.00 40.22  ? 315 TRP B CH2   1 
ATOM   6511  N  N     . ASN B 1 316 ? -24.623 33.399  -35.496  1.00 39.42  ? 316 ASN B N     1 
ATOM   6512  C  CA    . ASN B 1 316 ? -23.985 34.098  -36.602  1.00 41.82  ? 316 ASN B CA    1 
ATOM   6513  C  C     . ASN B 1 316 ? -23.775 33.121  -37.748  1.00 39.12  ? 316 ASN B C     1 
ATOM   6514  O  O     . ASN B 1 316 ? -22.982 32.199  -37.628  1.00 37.46  ? 316 ASN B O     1 
ATOM   6515  C  CB    . ASN B 1 316 ? -22.697 34.751  -36.118  1.00 40.76  ? 316 ASN B CB    1 
ATOM   6516  C  CG    . ASN B 1 316 ? -22.959 35.632  -34.912  1.00 39.92  ? 316 ASN B CG    1 
ATOM   6517  O  OD1   . ASN B 1 316 ? -23.458 36.745  -35.036  1.00 42.13  ? 316 ASN B OD1   1 
ATOM   6518  N  ND2   . ASN B 1 316 ? -22.713 35.105  -33.733  1.00 41.89  ? 316 ASN B ND2   1 
ATOM   6519  N  N     . PHE B 1 317 ? -24.564 33.294  -38.812  1.00 39.07  ? 317 PHE B N     1 
ATOM   6520  C  CA    . PHE B 1 317 ? -24.520 32.405  -39.958  1.00 39.57  ? 317 PHE B CA    1 
ATOM   6521  C  C     . PHE B 1 317 ? -23.603 32.984  -41.029  1.00 39.07  ? 317 PHE B C     1 
ATOM   6522  O  O     . PHE B 1 317 ? -23.898 34.020  -41.605  1.00 42.02  ? 317 PHE B O     1 
ATOM   6523  C  CB    . PHE B 1 317 ? -25.936 32.112  -40.461  1.00 39.95  ? 317 PHE B CB    1 
ATOM   6524  C  CG    . PHE B 1 317 ? -26.009 31.455  -41.816  1.00 40.19  ? 317 PHE B CG    1 
ATOM   6525  C  CD1   . PHE B 1 317 ? -25.041 30.546  -42.237  1.00 43.39  ? 317 PHE B CD1   1 
ATOM   6526  C  CD2   . PHE B 1 317 ? -27.057 31.739  -42.670  1.00 38.05  ? 317 PHE B CD2   1 
ATOM   6527  C  CE1   . PHE B 1 317 ? -25.115 29.945  -43.487  1.00 42.58  ? 317 PHE B CE1   1 
ATOM   6528  C  CE2   . PHE B 1 317 ? -27.130 31.147  -43.928  1.00 39.08  ? 317 PHE B CE2   1 
ATOM   6529  C  CZ    . PHE B 1 317 ? -26.165 30.243  -44.331  1.00 39.41  ? 317 PHE B CZ    1 
ATOM   6530  N  N     . CYS B 1 318 ? -22.497 32.267  -41.259  1.00 42.39  ? 318 CYS B N     1 
ATOM   6531  C  CA    . CYS B 1 318 ? -21.540 32.523  -42.323  1.00 45.23  ? 318 CYS B CA    1 
ATOM   6532  C  C     . CYS B 1 318 ? -21.724 31.529  -43.465  1.00 39.45  ? 318 CYS B C     1 
ATOM   6533  O  O     . CYS B 1 318 ? -21.808 30.328  -43.240  1.00 42.61  ? 318 CYS B O     1 
ATOM   6534  C  CB    . CYS B 1 318 ? -20.118 32.432  -41.790  1.00 47.46  ? 318 CYS B CB    1 
ATOM   6535  S  SG    . CYS B 1 318 ? -19.630 33.983  -41.001  1.00 49.96  ? 318 CYS B SG    1 
ATOM   6536  N  N     . GLY B 1 319 ? -21.873 32.074  -44.672  1.00 38.06  ? 319 GLY B N     1 
ATOM   6537  C  CA    . GLY B 1 319 ? -21.913 31.307  -45.899  1.00 41.59  ? 319 GLY B CA    1 
ATOM   6538  C  C     . GLY B 1 319 ? -21.311 32.116  -47.028  1.00 40.58  ? 319 GLY B C     1 
ATOM   6539  O  O     . GLY B 1 319 ? -20.878 33.250  -46.822  1.00 38.72  ? 319 GLY B O     1 
ATOM   6540  N  N     . ALA B 1 320 ? -21.287 31.529  -48.221  1.00 40.05  ? 320 ALA B N     1 
ATOM   6541  C  CA    . ALA B 1 320 ? -20.818 32.293  -49.355  1.00 41.60  ? 320 ALA B CA    1 
ATOM   6542  C  C     . ALA B 1 320 ? -21.515 31.840  -50.621  1.00 41.02  ? 320 ALA B C     1 
ATOM   6543  O  O     . ALA B 1 320 ? -21.837 30.668  -50.780  1.00 38.75  ? 320 ALA B O     1 
ATOM   6544  C  CB    . ALA B 1 320 ? -19.320 32.164  -49.491  1.00 41.55  ? 320 ALA B CB    1 
ATOM   6545  N  N     . LEU B 1 321 ? -21.637 32.795  -51.533  1.00 42.48  ? 321 LEU B N     1 
ATOM   6546  C  CA    . LEU B 1 321 ? -22.160 32.566  -52.866  1.00 42.00  ? 321 LEU B CA    1 
ATOM   6547  C  C     . LEU B 1 321 ? -20.975 32.446  -53.819  1.00 40.57  ? 321 LEU B C     1 
ATOM   6548  O  O     . LEU B 1 321 ? -19.998 33.157  -53.650  1.00 43.78  ? 321 LEU B O     1 
ATOM   6549  C  CB    . LEU B 1 321 ? -23.038 33.760  -53.229  1.00 41.73  ? 321 LEU B CB    1 
ATOM   6550  C  CG    . LEU B 1 321 ? -24.032 34.182  -52.148  1.00 45.21  ? 321 LEU B CG    1 
ATOM   6551  C  CD1   . LEU B 1 321 ? -24.615 35.564  -52.441  1.00 47.09  ? 321 LEU B CD1   1 
ATOM   6552  C  CD2   . LEU B 1 321 ? -25.125 33.144  -52.008  1.00 43.22  ? 321 LEU B CD2   1 
ATOM   6553  N  N     . TYR B 1 322 ? -21.078 31.552  -54.810  1.00 40.50  ? 322 TYR B N     1 
ATOM   6554  C  CA    . TYR B 1 322 ? -20.028 31.329  -55.791  1.00 38.64  ? 322 TYR B CA    1 
ATOM   6555  C  C     . TYR B 1 322 ? -20.664 31.286  -57.169  1.00 42.67  ? 322 TYR B C     1 
ATOM   6556  O  O     . TYR B 1 322 ? -21.795 30.820  -57.303  1.00 46.34  ? 322 TYR B O     1 
ATOM   6557  C  CB    . TYR B 1 322 ? -19.301 29.999  -55.554  1.00 38.53  ? 322 TYR B CB    1 
ATOM   6558  C  CG    . TYR B 1 322 ? -18.822 29.774  -54.141  1.00 39.47  ? 322 TYR B CG    1 
ATOM   6559  C  CD1   . TYR B 1 322 ? -19.689 29.342  -53.152  1.00 39.40  ? 322 TYR B CD1   1 
ATOM   6560  C  CD2   . TYR B 1 322 ? -17.499 29.983  -53.788  1.00 42.65  ? 322 TYR B CD2   1 
ATOM   6561  C  CE1   . TYR B 1 322 ? -19.273 29.174  -51.846  1.00 39.23  ? 322 TYR B CE1   1 
ATOM   6562  C  CE2   . TYR B 1 322 ? -17.056 29.776  -52.494  1.00 39.22  ? 322 TYR B CE2   1 
ATOM   6563  C  CZ    . TYR B 1 322 ? -17.945 29.375  -51.517  1.00 39.53  ? 322 TYR B CZ    1 
ATOM   6564  O  OH    . TYR B 1 322 ? -17.506 29.182  -50.237  1.00 39.16  ? 322 TYR B OH    1 
ATOM   6565  N  N     . GLY B 1 323 ? -19.922 31.746  -58.175  1.00 42.91  ? 323 GLY B N     1 
ATOM   6566  C  CA    . GLY B 1 323 ? -20.348 31.647  -59.559  1.00 42.52  ? 323 GLY B CA    1 
ATOM   6567  C  C     . GLY B 1 323 ? -20.630 33.010  -60.186  1.00 43.22  ? 323 GLY B C     1 
ATOM   6568  O  O     . GLY B 1 323 ? -20.381 34.054  -59.589  1.00 44.46  ? 323 GLY B O     1 
ATOM   6569  N  N     . PRO B 1 324 ? -21.187 33.029  -61.412  1.00 44.74  ? 324 PRO B N     1 
ATOM   6570  C  CA    . PRO B 1 324 ? -21.568 34.277  -62.065  1.00 43.24  ? 324 PRO B CA    1 
ATOM   6571  C  C     . PRO B 1 324 ? -22.559 35.086  -61.234  1.00 46.38  ? 324 PRO B C     1 
ATOM   6572  O  O     . PRO B 1 324 ? -23.412 34.529  -60.536  1.00 43.98  ? 324 PRO B O     1 
ATOM   6573  C  CB    . PRO B 1 324 ? -22.202 33.851  -63.395  1.00 43.16  ? 324 PRO B CB    1 
ATOM   6574  C  CG    . PRO B 1 324 ? -21.880 32.381  -63.574  1.00 44.81  ? 324 PRO B CG    1 
ATOM   6575  C  CD    . PRO B 1 324 ? -21.442 31.835  -62.233  1.00 47.52  ? 324 PRO B CD    1 
ATOM   6576  N  N     . PRO B 1 325 ? -22.456 36.431  -61.290  1.00 46.89  ? 325 PRO B N     1 
ATOM   6577  C  CA    . PRO B 1 325 ? -23.342 37.327  -60.555  1.00 49.10  ? 325 PRO B CA    1 
ATOM   6578  C  C     . PRO B 1 325 ? -24.831 37.012  -60.648  1.00 49.58  ? 325 PRO B C     1 
ATOM   6579  O  O     . PRO B 1 325 ? -25.536 37.138  -59.653  1.00 57.22  ? 325 PRO B O     1 
ATOM   6580  C  CB    . PRO B 1 325 ? -23.054 38.708  -61.174  1.00 50.14  ? 325 PRO B CB    1 
ATOM   6581  C  CG    . PRO B 1 325 ? -21.622 38.614  -61.618  1.00 52.75  ? 325 PRO B CG    1 
ATOM   6582  C  CD    . PRO B 1 325 ? -21.431 37.171  -62.042  1.00 51.70  ? 325 PRO B CD    1 
ATOM   6583  N  N     . PRO B 1 326 ? -25.386 36.665  -61.829  1.00 54.28  ? 326 PRO B N     1 
ATOM   6584  C  CA    . PRO B 1 326 ? -26.806 36.329  -61.924  1.00 52.30  ? 326 PRO B CA    1 
ATOM   6585  C  C     . PRO B 1 326 ? -27.146 35.071  -61.131  1.00 54.63  ? 326 PRO B C     1 
ATOM   6586  O  O     . PRO B 1 326 ? -28.241 34.980  -60.573  1.00 52.99  ? 326 PRO B O     1 
ATOM   6587  C  CB    . PRO B 1 326 ? -27.064 36.112  -63.422  1.00 49.16  ? 326 PRO B CB    1 
ATOM   6588  C  CG    . PRO B 1 326 ? -25.875 36.720  -64.118  1.00 46.27  ? 326 PRO B CG    1 
ATOM   6589  C  CD    . PRO B 1 326 ? -24.722 36.612  -63.141  1.00 51.14  ? 326 PRO B CD    1 
ATOM   6590  N  N     . VAL B 1 327 ? -26.204 34.115  -61.067  1.00 51.19  ? 327 VAL B N     1 
ATOM   6591  C  CA    . VAL B 1 327 ? -26.417 32.920  -60.266  1.00 48.02  ? 327 VAL B CA    1 
ATOM   6592  C  C     . VAL B 1 327 ? -26.415 33.328  -58.791  1.00 48.16  ? 327 VAL B C     1 
ATOM   6593  O  O     . VAL B 1 327 ? -27.384 33.072  -58.071  1.00 43.80  ? 327 VAL B O     1 
ATOM   6594  C  CB    . VAL B 1 327 ? -25.392 31.817  -60.602  1.00 52.81  ? 327 VAL B CB    1 
ATOM   6595  C  CG1   . VAL B 1 327 ? -25.379 30.680  -59.587  1.00 47.44  ? 327 VAL B CG1   1 
ATOM   6596  C  CG2   . VAL B 1 327 ? -25.642 31.259  -61.998  1.00 52.48  ? 327 VAL B CG2   1 
ATOM   6597  N  N     . MET B 1 328 ? -25.368 34.051  -58.375  1.00 45.52  ? 328 MET B N     1 
ATOM   6598  C  CA    . MET B 1 328 ? -25.243 34.479  -56.992  1.00 47.68  ? 328 MET B CA    1 
ATOM   6599  C  C     . MET B 1 328 ? -26.467 35.298  -56.570  1.00 45.61  ? 328 MET B C     1 
ATOM   6600  O  O     . MET B 1 328 ? -26.960 35.132  -55.460  1.00 44.57  ? 328 MET B O     1 
ATOM   6601  C  CB    . MET B 1 328 ? -23.964 35.298  -56.783  1.00 45.29  ? 328 MET B CB    1 
ATOM   6602  C  CG    . MET B 1 328 ? -22.697 34.456  -56.878  1.00 45.91  ? 328 MET B CG    1 
ATOM   6603  S  SD    . MET B 1 328 ? -21.209 35.290  -56.286  1.00 46.28  ? 328 MET B SD    1 
ATOM   6604  C  CE    . MET B 1 328 ? -21.204 36.765  -57.311  1.00 47.75  ? 328 MET B CE    1 
ATOM   6605  N  N     . ASP B 1 329 ? -26.954 36.175  -57.454  1.00 45.07  ? 329 ASP B N     1 
ATOM   6606  C  CA    . ASP B 1 329 ? -28.112 37.002  -57.155  1.00 49.64  ? 329 ASP B CA    1 
ATOM   6607  C  C     . ASP B 1 329 ? -29.349 36.144  -56.911  1.00 45.87  ? 329 ASP B C     1 
ATOM   6608  O  O     . ASP B 1 329 ? -30.133 36.446  -56.019  1.00 53.93  ? 329 ASP B O     1 
ATOM   6609  C  CB    . ASP B 1 329 ? -28.400 38.013  -58.273  1.00 52.23  ? 329 ASP B CB    1 
ATOM   6610  C  CG    . ASP B 1 329 ? -27.419 39.168  -58.296  1.00 54.60  ? 329 ASP B CG    1 
ATOM   6611  O  OD1   . ASP B 1 329 ? -26.654 39.268  -57.337  1.00 57.34  ? 329 ASP B OD1   1 
ATOM   6612  O  OD2   . ASP B 1 329 ? -27.409 39.933  -59.284  1.00 60.72  ? 329 ASP B OD2   1 
ATOM   6613  N  N     . THR B 1 330 ? -29.552 35.106  -57.729  1.00 47.62  ? 330 THR B N     1 
ATOM   6614  C  CA    . THR B 1 330 ? -30.701 34.227  -57.564  1.00 47.77  ? 330 THR B CA    1 
ATOM   6615  C  C     . THR B 1 330 ? -30.605 33.448  -56.257  1.00 43.17  ? 330 THR B C     1 
ATOM   6616  O  O     . THR B 1 330 ? -31.596 33.340  -55.544  1.00 45.30  ? 330 THR B O     1 
ATOM   6617  C  CB    . THR B 1 330 ? -30.847 33.240  -58.723  1.00 48.04  ? 330 THR B CB    1 
ATOM   6618  O  OG1   . THR B 1 330 ? -30.888 34.039  -59.893  1.00 51.89  ? 330 THR B OG1   1 
ATOM   6619  C  CG2   . THR B 1 330 ? -32.085 32.376  -58.622  1.00 51.55  ? 330 THR B CG2   1 
ATOM   6620  N  N     . LEU B 1 331 ? -29.422 32.891  -55.959  1.00 42.90  ? 331 LEU B N     1 
ATOM   6621  C  CA    . LEU B 1 331 ? -29.250 32.125  -54.732  1.00 41.86  ? 331 LEU B CA    1 
ATOM   6622  C  C     . LEU B 1 331 ? -29.446 33.050  -53.521  1.00 39.24  ? 331 LEU B C     1 
ATOM   6623  O  O     . LEU B 1 331 ? -30.129 32.707  -52.556  1.00 39.56  ? 331 LEU B O     1 
ATOM   6624  C  CB    . LEU B 1 331 ? -27.860 31.489  -54.724  1.00 45.08  ? 331 LEU B CB    1 
ATOM   6625  C  CG    . LEU B 1 331 ? -27.529 30.502  -55.842  1.00 45.82  ? 331 LEU B CG    1 
ATOM   6626  C  CD1   . LEU B 1 331 ? -26.186 29.835  -55.565  1.00 45.97  ? 331 LEU B CD1   1 
ATOM   6627  C  CD2   . LEU B 1 331 ? -28.612 29.451  -56.024  1.00 44.69  ? 331 LEU B CD2   1 
ATOM   6628  N  N     . TRP B 1 332 ? -28.839 34.238  -53.564  1.00 41.95  ? 332 TRP B N     1 
ATOM   6629  C  CA    . TRP B 1 332 ? -28.995 35.196  -52.478  1.00 44.84  ? 332 TRP B CA    1 
ATOM   6630  C  C     . TRP B 1 332 ? -30.472 35.512  -52.218  1.00 43.56  ? 332 TRP B C     1 
ATOM   6631  O  O     . TRP B 1 332 ? -30.900 35.625  -51.063  1.00 46.40  ? 332 TRP B O     1 
ATOM   6632  C  CB    . TRP B 1 332 ? -28.226 36.495  -52.753  1.00 45.89  ? 332 TRP B CB    1 
ATOM   6633  C  CG    . TRP B 1 332 ? -28.348 37.465  -51.621  1.00 47.66  ? 332 TRP B CG    1 
ATOM   6634  C  CD1   . TRP B 1 332 ? -28.850 38.734  -51.666  1.00 49.11  ? 332 TRP B CD1   1 
ATOM   6635  C  CD2   . TRP B 1 332 ? -28.009 37.212  -50.245  1.00 48.15  ? 332 TRP B CD2   1 
ATOM   6636  N  NE1   . TRP B 1 332 ? -28.819 39.296  -50.421  1.00 48.64  ? 332 TRP B NE1   1 
ATOM   6637  C  CE2   . TRP B 1 332 ? -28.294 38.397  -49.531  1.00 44.11  ? 332 TRP B CE2   1 
ATOM   6638  C  CE3   . TRP B 1 332 ? -27.442 36.126  -49.557  1.00 45.47  ? 332 TRP B CE3   1 
ATOM   6639  C  CZ2   . TRP B 1 332 ? -28.060 38.509  -48.160  1.00 44.23  ? 332 TRP B CZ2   1 
ATOM   6640  C  CZ3   . TRP B 1 332 ? -27.199 36.241  -48.206  1.00 44.67  ? 332 TRP B CZ3   1 
ATOM   6641  C  CH2   . TRP B 1 332 ? -27.520 37.413  -47.516  1.00 47.21  ? 332 TRP B CH2   1 
ATOM   6642  N  N     . THR B 1 333 ? -31.241 35.757  -53.284  1.00 43.30  ? 333 THR B N     1 
ATOM   6643  C  CA    . THR B 1 333 ? -32.662 36.051  -53.122  1.00 41.29  ? 333 THR B CA    1 
ATOM   6644  C  C     . THR B 1 333 ? -33.321 34.965  -52.296  1.00 41.65  ? 333 THR B C     1 
ATOM   6645  O  O     . THR B 1 333 ? -34.023 35.289  -51.342  1.00 48.20  ? 333 THR B O     1 
ATOM   6646  C  CB    . THR B 1 333 ? -33.368 36.207  -54.470  1.00 47.78  ? 333 THR B CB    1 
ATOM   6647  O  OG1   . THR B 1 333 ? -32.776 37.375  -55.025  1.00 48.29  ? 333 THR B OG1   1 
ATOM   6648  C  CG2   . THR B 1 333 ? -34.872 36.363  -54.366  1.00 48.14  ? 333 THR B CG2   1 
ATOM   6649  N  N     . ALA B 1 334 ? -33.000 33.692  -52.605  1.00 41.73  ? 334 ALA B N     1 
ATOM   6650  C  CA    . ALA B 1 334 ? -33.600 32.565  -51.901  1.00 41.10  ? 334 ALA B CA    1 
ATOM   6651  C  C     . ALA B 1 334 ? -33.152 32.543  -50.446  1.00 39.84  ? 334 ALA B C     1 
ATOM   6652  O  O     . ALA B 1 334 ? -33.966 32.359  -49.556  1.00 42.37  ? 334 ALA B O     1 
ATOM   6653  C  CB    . ALA B 1 334 ? -33.292 31.256  -52.588  1.00 41.52  ? 334 ALA B CB    1 
ATOM   6654  N  N     . ILE B 1 335 ? -31.858 32.768  -50.204  1.00 42.87  ? 335 ILE B N     1 
ATOM   6655  C  CA    . ILE B 1 335 ? -31.329 32.683  -48.855  1.00 40.90  ? 335 ILE B CA    1 
ATOM   6656  C  C     . ILE B 1 335 ? -31.866 33.829  -47.994  1.00 37.99  ? 335 ILE B C     1 
ATOM   6657  O  O     . ILE B 1 335 ? -32.372 33.585  -46.906  1.00 40.40  ? 335 ILE B O     1 
ATOM   6658  C  CB    . ILE B 1 335 ? -29.791 32.615  -48.894  1.00 41.19  ? 335 ILE B CB    1 
ATOM   6659  C  CG1   . ILE B 1 335 ? -29.313 31.347  -49.614  1.00 41.89  ? 335 ILE B CG1   1 
ATOM   6660  C  CG2   . ILE B 1 335 ? -29.221 32.724  -47.479  1.00 42.16  ? 335 ILE B CG2   1 
ATOM   6661  C  CD1   . ILE B 1 335 ? -27.925 31.459  -50.226  1.00 41.20  ? 335 ILE B CD1   1 
ATOM   6662  N  N     . ARG B 1 336 ? -31.803 35.068  -48.489  1.00 41.70  ? 336 ARG B N     1 
ATOM   6663  C  CA    . ARG B 1 336 ? -32.223 36.242  -47.726  1.00 42.66  ? 336 ARG B CA    1 
ATOM   6664  C  C     . ARG B 1 336 ? -33.715 36.157  -47.387  1.00 43.71  ? 336 ARG B C     1 
ATOM   6665  O  O     . ARG B 1 336 ? -34.120 36.337  -46.242  1.00 46.63  ? 336 ARG B O     1 
ATOM   6666  C  CB    . ARG B 1 336 ? -31.959 37.529  -48.530  1.00 46.46  ? 336 ARG B CB    1 
ATOM   6667  C  CG    . ARG B 1 336 ? -32.167 38.830  -47.761  1.00 49.27  ? 336 ARG B CG    1 
ATOM   6668  C  CD    . ARG B 1 336 ? -32.292 40.080  -48.628  1.00 56.19  ? 336 ARG B CD    1 
ATOM   6669  N  NE    . ARG B 1 336 ? -31.983 41.312  -47.892  1.00 63.68  ? 336 ARG B NE    1 
ATOM   6670  C  CZ    . ARG B 1 336 ? -32.735 41.873  -46.934  1.00 73.09  ? 336 ARG B CZ    1 
ATOM   6671  N  NH1   . ARG B 1 336 ? -34.000 41.525  -46.761  1.00 73.83  ? 336 ARG B NH1   1 
ATOM   6672  N  NH2   . ARG B 1 336 ? -32.232 42.841  -46.182  1.00 65.77  ? 336 ARG B NH2   1 
ATOM   6673  N  N     . ASP B 1 337 ? -34.542 35.877  -48.391  1.00 46.55  ? 337 ASP B N     1 
ATOM   6674  C  CA    . ASP B 1 337 ? -35.970 35.779  -48.162  1.00 46.65  ? 337 ASP B CA    1 
ATOM   6675  C  C     . ASP B 1 337 ? -36.286 34.657  -47.178  1.00 48.20  ? 337 ASP B C     1 
ATOM   6676  O  O     . ASP B 1 337 ? -37.368 34.675  -46.609  1.00 48.40  ? 337 ASP B O     1 
ATOM   6677  C  CB    . ASP B 1 337 ? -36.762 35.556  -49.452  1.00 46.92  ? 337 ASP B CB    1 
ATOM   6678  C  CG    . ASP B 1 337 ? -36.729 36.709  -50.441  1.00 55.22  ? 337 ASP B CG    1 
ATOM   6679  O  OD1   . ASP B 1 337 ? -36.121 37.768  -50.131  1.00 54.28  ? 337 ASP B OD1   1 
ATOM   6680  O  OD2   . ASP B 1 337 ? -37.313 36.527  -51.532  1.00 61.43  ? 337 ASP B OD2   1 
ATOM   6681  N  N     . SER B 1 338 ? -35.384 33.677  -46.985  1.00 45.85  ? 338 SER B N     1 
ATOM   6682  C  CA    . SER B 1 338 ? -35.657 32.608  -46.029  1.00 42.94  ? 338 SER B CA    1 
ATOM   6683  C  C     . SER B 1 338 ? -35.538 33.090  -44.583  1.00 43.20  ? 338 SER B C     1 
ATOM   6684  O  O     . SER B 1 338 ? -36.004 32.390  -43.686  1.00 44.30  ? 338 SER B O     1 
ATOM   6685  C  CB    . SER B 1 338 ? -34.747 31.414  -46.213  1.00 43.57  ? 338 SER B CB    1 
ATOM   6686  O  OG    . SER B 1 338 ? -34.973 30.737  -47.434  1.00 41.05  ? 338 SER B OG    1 
ATOM   6687  N  N     . PHE B 1 339 ? -34.849 34.220  -44.332  1.00 39.34  ? 339 PHE B N     1 
ATOM   6688  C  CA    . PHE B 1 339 ? -34.538 34.618  -42.965  1.00 39.26  ? 339 PHE B CA    1 
ATOM   6689  C  C     . PHE B 1 339 ? -35.054 36.022  -42.623  1.00 41.53  ? 339 PHE B C     1 
ATOM   6690  O  O     . PHE B 1 339 ? -34.913 36.451  -41.478  1.00 41.90  ? 339 PHE B O     1 
ATOM   6691  C  CB    . PHE B 1 339 ? -33.020 34.569  -42.735  1.00 40.62  ? 339 PHE B CB    1 
ATOM   6692  C  CG    . PHE B 1 339 ? -32.421 33.185  -42.844  1.00 35.21  ? 339 PHE B CG    1 
ATOM   6693  C  CD1   . PHE B 1 339 ? -32.662 32.235  -41.881  1.00 36.67  ? 339 PHE B CD1   1 
ATOM   6694  C  CD2   . PHE B 1 339 ? -31.634 32.835  -43.929  1.00 39.85  ? 339 PHE B CD2   1 
ATOM   6695  C  CE1   . PHE B 1 339 ? -32.144 30.950  -41.994  1.00 36.62  ? 339 PHE B CE1   1 
ATOM   6696  C  CE2   . PHE B 1 339 ? -31.116 31.553  -44.050  1.00 40.98  ? 339 PHE B CE2   1 
ATOM   6697  C  CZ    . PHE B 1 339 ? -31.360 30.619  -43.071  1.00 38.88  ? 339 PHE B CZ    1 
ATOM   6698  N  N     . ALA B 1 340 ? -35.636 36.723  -43.603  1.00 42.22  ? 340 ALA B N     1 
ATOM   6699  C  CA    . ALA B 1 340 ? -35.791 38.179  -43.558  1.00 48.26  ? 340 ALA B CA    1 
ATOM   6700  C  C     . ALA B 1 340 ? -36.844 38.616  -42.543  1.00 47.16  ? 340 ALA B C     1 
ATOM   6701  O  O     . ALA B 1 340 ? -36.740 39.713  -42.014  1.00 51.56  ? 340 ALA B O     1 
ATOM   6702  C  CB    . ALA B 1 340 ? -36.158 38.710  -44.924  1.00 47.23  ? 340 ALA B CB    1 
ATOM   6703  N  N     . ASP B 1 341 ? -37.833 37.747  -42.282  1.00 48.80  ? 341 ASP B N     1 
ATOM   6704  C  CA    . ASP B 1 341 ? -38.979 38.030  -41.429  1.00 48.31  ? 341 ASP B CA    1 
ATOM   6705  C  C     . ASP B 1 341 ? -38.713 37.631  -39.980  1.00 51.04  ? 341 ASP B C     1 
ATOM   6706  O  O     . ASP B 1 341 ? -39.615 37.691  -39.152  1.00 57.48  ? 341 ASP B O     1 
ATOM   6707  C  CB    . ASP B 1 341 ? -40.195 37.238  -41.902  1.00 51.23  ? 341 ASP B CB    1 
ATOM   6708  C  CG    . ASP B 1 341 ? -39.978 35.738  -41.754  1.00 60.75  ? 341 ASP B CG    1 
ATOM   6709  O  OD1   . ASP B 1 341 ? -38.855 35.277  -42.059  1.00 70.78  ? 341 ASP B OD1   1 
ATOM   6710  O  OD2   . ASP B 1 341 ? -40.909 35.043  -41.335  1.00 59.62  ? 341 ASP B OD2   1 
ATOM   6711  N  N     . ILE B 1 342 ? -37.499 37.188  -39.652  1.00 52.65  ? 342 ILE B N     1 
ATOM   6712  C  CA    . ILE B 1 342 ? -37.194 36.867  -38.266  1.00 50.58  ? 342 ILE B CA    1 
ATOM   6713  C  C     . ILE B 1 342 ? -36.840 38.170  -37.548  1.00 51.47  ? 342 ILE B C     1 
ATOM   6714  O  O     . ILE B 1 342 ? -35.904 38.863  -37.939  1.00 55.71  ? 342 ILE B O     1 
ATOM   6715  C  CB    . ILE B 1 342 ? -36.070 35.815  -38.163  1.00 48.24  ? 342 ILE B CB    1 
ATOM   6716  C  CG1   . ILE B 1 342 ? -36.484 34.467  -38.759  1.00 45.92  ? 342 ILE B CG1   1 
ATOM   6717  C  CG2   . ILE B 1 342 ? -35.614 35.657  -36.722  1.00 48.93  ? 342 ILE B CG2   1 
ATOM   6718  C  CD1   . ILE B 1 342 ? -35.315 33.564  -39.087  1.00 45.49  ? 342 ILE B CD1   1 
ATOM   6719  N  N     . PRO B 1 343 ? -37.577 38.568  -36.486  1.00 55.80  ? 343 PRO B N     1 
ATOM   6720  C  CA    . PRO B 1 343 ? -37.306 39.837  -35.817  1.00 51.61  ? 343 PRO B CA    1 
ATOM   6721  C  C     . PRO B 1 343 ? -35.859 39.866  -35.343  1.00 47.60  ? 343 PRO B C     1 
ATOM   6722  O  O     . PRO B 1 343 ? -35.409 38.902  -34.742  1.00 43.92  ? 343 PRO B O     1 
ATOM   6723  C  CB    . PRO B 1 343 ? -38.286 39.846  -34.634  1.00 54.48  ? 343 PRO B CB    1 
ATOM   6724  C  CG    . PRO B 1 343 ? -39.402 38.923  -35.066  1.00 54.08  ? 343 PRO B CG    1 
ATOM   6725  C  CD    . PRO B 1 343 ? -38.706 37.844  -35.871  1.00 57.77  ? 343 PRO B CD    1 
ATOM   6726  N  N     . GLY B 1 344 ? -35.148 40.962  -35.637  1.00 46.78  ? 344 GLY B N     1 
ATOM   6727  C  CA    . GLY B 1 344 ? -33.786 41.157  -35.172  1.00 43.93  ? 344 GLY B CA    1 
ATOM   6728  C  C     . GLY B 1 344 ? -32.729 40.734  -36.199  1.00 45.85  ? 344 GLY B C     1 
ATOM   6729  O  O     . GLY B 1 344 ? -31.544 40.982  -36.001  1.00 46.24  ? 344 GLY B O     1 
ATOM   6730  N  N     . VAL B 1 345 ? -33.138 40.094  -37.299  1.00 48.45  ? 345 VAL B N     1 
ATOM   6731  C  CA    . VAL B 1 345 ? -32.171 39.516  -38.217  1.00 45.11  ? 345 VAL B CA    1 
ATOM   6732  C  C     . VAL B 1 345 ? -31.388 40.644  -38.874  1.00 42.83  ? 345 VAL B C     1 
ATOM   6733  O  O     . VAL B 1 345 ? -31.975 41.661  -39.227  1.00 41.92  ? 345 VAL B O     1 
ATOM   6734  C  CB    . VAL B 1 345 ? -32.859 38.635  -39.279  1.00 50.77  ? 345 VAL B CB    1 
ATOM   6735  C  CG1   . VAL B 1 345 ? -33.798 39.432  -40.181  1.00 49.55  ? 345 VAL B CG1   1 
ATOM   6736  C  CG2   . VAL B 1 345 ? -31.845 37.868  -40.118  1.00 50.13  ? 345 VAL B CG2   1 
ATOM   6737  N  N     . LYS B 1 346 ? -30.081 40.444  -39.102  1.00 43.58  ? 346 LYS B N     1 
ATOM   6738  C  CA    . LYS B 1 346 ? -29.331 41.393  -39.917  1.00 47.43  ? 346 LYS B CA    1 
ATOM   6739  C  C     . LYS B 1 346 ? -28.450 40.664  -40.924  1.00 42.69  ? 346 LYS B C     1 
ATOM   6740  O  O     . LYS B 1 346 ? -27.953 39.585  -40.658  1.00 41.16  ? 346 LYS B O     1 
ATOM   6741  C  CB    . LYS B 1 346 ? -28.474 42.329  -39.062  1.00 51.31  ? 346 LYS B CB    1 
ATOM   6742  C  CG    . LYS B 1 346 ? -29.223 43.141  -38.014  1.00 55.88  ? 346 LYS B CG    1 
ATOM   6743  C  CD    . LYS B 1 346 ? -28.278 44.016  -37.218  1.00 64.95  ? 346 LYS B CD    1 
ATOM   6744  C  CE    . LYS B 1 346 ? -28.959 44.897  -36.187  1.00 76.99  ? 346 LYS B CE    1 
ATOM   6745  N  NZ    . LYS B 1 346 ? -29.219 44.171  -34.920  1.00 81.22  ? 346 LYS B NZ    1 
ATOM   6746  N  N     . PHE B 1 347 ? -28.217 41.317  -42.065  1.00 42.72  ? 347 PHE B N     1 
ATOM   6747  C  CA    . PHE B 1 347 ? -27.516 40.730  -43.190  1.00 40.90  ? 347 PHE B CA    1 
ATOM   6748  C  C     . PHE B 1 347 ? -26.284 41.561  -43.509  1.00 41.06  ? 347 PHE B C     1 
ATOM   6749  O  O     . PHE B 1 347 ? -26.403 42.775  -43.650  1.00 45.24  ? 347 PHE B O     1 
ATOM   6750  C  CB    . PHE B 1 347 ? -28.434 40.752  -44.410  1.00 43.38  ? 347 PHE B CB    1 
ATOM   6751  C  CG    . PHE B 1 347 ? -29.707 39.960  -44.261  1.00 46.84  ? 347 PHE B CG    1 
ATOM   6752  C  CD1   . PHE B 1 347 ? -29.723 38.587  -44.496  1.00 47.31  ? 347 PHE B CD1   1 
ATOM   6753  C  CD2   . PHE B 1 347 ? -30.885 40.584  -43.872  1.00 42.89  ? 347 PHE B CD2   1 
ATOM   6754  C  CE1   . PHE B 1 347 ? -30.904 37.864  -44.384  1.00 41.77  ? 347 PHE B CE1   1 
ATOM   6755  C  CE2   . PHE B 1 347 ? -32.057 39.855  -43.734  1.00 45.49  ? 347 PHE B CE2   1 
ATOM   6756  C  CZ    . PHE B 1 347 ? -32.057 38.491  -43.973  1.00 44.19  ? 347 PHE B CZ    1 
ATOM   6757  N  N     . TYR B 1 348 ? -25.117 40.931  -43.634  1.00 42.54  ? 348 TYR B N     1 
ATOM   6758  C  CA    . TYR B 1 348 ? -23.908 41.686  -43.942  1.00 41.93  ? 348 TYR B CA    1 
ATOM   6759  C  C     . TYR B 1 348 ? -23.091 41.037  -45.049  1.00 41.65  ? 348 TYR B C     1 
ATOM   6760  O  O     . TYR B 1 348 ? -22.874 39.817  -45.063  1.00 41.47  ? 348 TYR B O     1 
ATOM   6761  C  CB    . TYR B 1 348 ? -22.959 41.830  -42.749  1.00 42.32  ? 348 TYR B CB    1 
ATOM   6762  C  CG    . TYR B 1 348 ? -23.529 42.394  -41.474  1.00 41.83  ? 348 TYR B CG    1 
ATOM   6763  C  CD1   . TYR B 1 348 ? -24.144 41.566  -40.553  1.00 37.16  ? 348 TYR B CD1   1 
ATOM   6764  C  CD2   . TYR B 1 348 ? -23.439 43.748  -41.177  1.00 42.66  ? 348 TYR B CD2   1 
ATOM   6765  C  CE1   . TYR B 1 348 ? -24.640 42.052  -39.365  1.00 39.37  ? 348 TYR B CE1   1 
ATOM   6766  C  CE2   . TYR B 1 348 ? -23.949 44.258  -39.998  1.00 39.20  ? 348 TYR B CE2   1 
ATOM   6767  C  CZ    . TYR B 1 348 ? -24.533 43.404  -39.083  1.00 44.05  ? 348 TYR B CZ    1 
ATOM   6768  O  OH    . TYR B 1 348 ? -25.055 43.857  -37.907  1.00 40.81  ? 348 TYR B OH    1 
ATOM   6769  N  N     . PHE B 1 349 ? -22.621 41.901  -45.959  1.00 42.09  ? 349 PHE B N     1 
ATOM   6770  C  CA    . PHE B 1 349 ? -21.546 41.582  -46.879  1.00 38.22  ? 349 PHE B CA    1 
ATOM   6771  C  C     . PHE B 1 349 ? -20.302 42.279  -46.357  1.00 40.42  ? 349 PHE B C     1 
ATOM   6772  O  O     . PHE B 1 349 ? -20.418 43.076  -45.438  1.00 40.54  ? 349 PHE B O     1 
ATOM   6773  C  CB    . PHE B 1 349 ? -21.952 41.969  -48.303  1.00 45.67  ? 349 PHE B CB    1 
ATOM   6774  C  CG    . PHE B 1 349 ? -23.007 41.053  -48.866  1.00 44.25  ? 349 PHE B CG    1 
ATOM   6775  C  CD1   . PHE B 1 349 ? -22.666 39.780  -49.306  1.00 47.26  ? 349 PHE B CD1   1 
ATOM   6776  C  CD2   . PHE B 1 349 ? -24.345 41.400  -48.825  1.00 46.71  ? 349 PHE B CD2   1 
ATOM   6777  C  CE1   . PHE B 1 349 ? -23.642 38.921  -49.798  1.00 48.35  ? 349 PHE B CE1   1 
ATOM   6778  C  CE2   . PHE B 1 349 ? -25.320 40.533  -49.302  1.00 47.99  ? 349 PHE B CE2   1 
ATOM   6779  C  CZ    . PHE B 1 349 ? -24.969 39.291  -49.779  1.00 45.10  ? 349 PHE B CZ    1 
ATOM   6780  N  N     . PRO B 1 350 ? -19.083 41.946  -46.851  1.00 39.31  ? 350 PRO B N     1 
ATOM   6781  C  CA    . PRO B 1 350 ? -17.851 42.462  -46.259  1.00 39.82  ? 350 PRO B CA    1 
ATOM   6782  C  C     . PRO B 1 350 ? -17.877 43.978  -46.115  1.00 43.66  ? 350 PRO B C     1 
ATOM   6783  O  O     . PRO B 1 350 ? -17.521 44.506  -45.067  1.00 45.71  ? 350 PRO B O     1 
ATOM   6784  C  CB    . PRO B 1 350 ? -16.774 41.947  -47.222  1.00 38.29  ? 350 PRO B CB    1 
ATOM   6785  C  CG    . PRO B 1 350 ? -17.351 40.615  -47.653  1.00 39.09  ? 350 PRO B CG    1 
ATOM   6786  C  CD    . PRO B 1 350 ? -18.814 40.944  -47.892  1.00 38.83  ? 350 PRO B CD    1 
ATOM   6787  N  N     . GLU B 1 351 ? -18.361 44.662  -47.150  1.00 48.52  ? 351 GLU B N     1 
ATOM   6788  C  CA    . GLU B 1 351 ? -18.335 46.110  -47.174  1.00 49.04  ? 351 GLU B CA    1 
ATOM   6789  C  C     . GLU B 1 351 ? -19.298 46.672  -46.134  1.00 51.06  ? 351 GLU B C     1 
ATOM   6790  O  O     . GLU B 1 351 ? -19.266 47.869  -45.908  1.00 49.54  ? 351 GLU B O     1 
ATOM   6791  C  CB    . GLU B 1 351 ? -18.642 46.662  -48.573  1.00 46.99  ? 351 GLU B CB    1 
ATOM   6792  C  CG    . GLU B 1 351 ? -20.032 46.366  -49.080  1.00 45.53  ? 351 GLU B CG    1 
ATOM   6793  C  CD    . GLU B 1 351 ? -20.227 44.967  -49.647  1.00 52.68  ? 351 GLU B CD    1 
ATOM   6794  O  OE1   . GLU B 1 351 ? -19.251 44.155  -49.616  1.00 48.74  ? 351 GLU B OE1   1 
ATOM   6795  O  OE2   . GLU B 1 351 ? -21.351 44.683  -50.112  1.00 49.46  ? 351 GLU B OE2   1 
ATOM   6796  N  N     . ASP B 1 352 ? -20.158 45.845  -45.520  1.00 50.55  ? 352 ASP B N     1 
ATOM   6797  C  CA    . ASP B 1 352 ? -21.037 46.323  -44.467  1.00 44.78  ? 352 ASP B CA    1 
ATOM   6798  C  C     . ASP B 1 352 ? -20.409 46.161  -43.089  1.00 44.92  ? 352 ASP B C     1 
ATOM   6799  O  O     . ASP B 1 352 ? -21.067 46.444  -42.101  1.00 48.50  ? 352 ASP B O     1 
ATOM   6800  C  CB    . ASP B 1 352 ? -22.365 45.569  -44.426  1.00 47.42  ? 352 ASP B CB    1 
ATOM   6801  C  CG    . ASP B 1 352 ? -23.130 45.664  -45.727  1.00 48.53  ? 352 ASP B CG    1 
ATOM   6802  O  OD1   . ASP B 1 352 ? -23.410 46.798  -46.149  1.00 53.67  ? 352 ASP B OD1   1 
ATOM   6803  O  OD2   . ASP B 1 352 ? -23.396 44.614  -46.316  1.00 40.88  ? 352 ASP B OD2   1 
ATOM   6804  N  N     . ARG B 1 353 ? -19.180 45.651  -42.990  1.00 45.03  ? 353 ARG B N     1 
ATOM   6805  C  CA    . ARG B 1 353 ? -18.598 45.448  -41.672  1.00 46.20  ? 353 ARG B CA    1 
ATOM   6806  C  C     . ARG B 1 353 ? -17.750 46.662  -41.290  1.00 48.52  ? 353 ARG B C     1 
ATOM   6807  O  O     . ARG B 1 353 ? -16.826 47.020  -41.999  1.00 49.96  ? 353 ARG B O     1 
ATOM   6808  C  CB    . ARG B 1 353 ? -17.762 44.168  -41.662  1.00 45.87  ? 353 ARG B CB    1 
ATOM   6809  C  CG    . ARG B 1 353 ? -18.537 42.896  -41.996  1.00 46.20  ? 353 ARG B CG    1 
ATOM   6810  C  CD    . ARG B 1 353 ? -19.706 42.569  -41.083  1.00 42.39  ? 353 ARG B CD    1 
ATOM   6811  N  NE    . ARG B 1 353 ? -19.273 42.128  -39.772  1.00 41.66  ? 353 ARG B NE    1 
ATOM   6812  C  CZ    . ARG B 1 353 ? -20.064 42.022  -38.707  1.00 40.63  ? 353 ARG B CZ    1 
ATOM   6813  N  NH1   . ARG B 1 353 ? -21.360 42.259  -38.793  1.00 39.26  ? 353 ARG B NH1   1 
ATOM   6814  N  NH2   . ARG B 1 353 ? -19.552 41.661  -37.548  1.00 37.73  ? 353 ARG B NH2   1 
ATOM   6815  N  N     . ARG B 1 354 ? -18.017 47.276  -40.136  1.00 49.74  ? 354 ARG B N     1 
ATOM   6816  C  CA    . ARG B 1 354 ? -17.346 48.526  -39.814  1.00 47.54  ? 354 ARG B CA    1 
ATOM   6817  C  C     . ARG B 1 354 ? -16.021 48.275  -39.097  1.00 46.98  ? 354 ARG B C     1 
ATOM   6818  O  O     . ARG B 1 354 ? -15.147 49.142  -39.113  1.00 49.21  ? 354 ARG B O     1 
ATOM   6819  C  CB    . ARG B 1 354 ? -18.278 49.447  -39.033  1.00 49.98  ? 354 ARG B CB    1 
ATOM   6820  C  CG    . ARG B 1 354 ? -18.682 48.914  -37.667  1.00 53.06  ? 354 ARG B CG    1 
ATOM   6821  C  CD    . ARG B 1 354 ? -19.923 49.646  -37.193  1.00 49.63  ? 354 ARG B CD    1 
ATOM   6822  N  NE    . ARG B 1 354 ? -20.464 49.020  -36.005  1.00 47.94  ? 354 ARG B NE    1 
ATOM   6823  C  CZ    . ARG B 1 354 ? -19.937 49.075  -34.791  1.00 46.31  ? 354 ARG B CZ    1 
ATOM   6824  N  NH1   . ARG B 1 354 ? -18.856 49.795  -34.546  1.00 53.51  ? 354 ARG B NH1   1 
ATOM   6825  N  NH2   . ARG B 1 354 ? -20.494 48.376  -33.821  1.00 46.57  ? 354 ARG B NH2   1 
ATOM   6826  N  N     . HIS B 1 355 ? -15.836 47.079  -38.520  1.00 40.62  ? 355 HIS B N     1 
ATOM   6827  C  CA    . HIS B 1 355 ? -14.556 46.729  -37.940  1.00 42.76  ? 355 HIS B CA    1 
ATOM   6828  C  C     . HIS B 1 355 ? -13.686 46.145  -39.040  1.00 45.34  ? 355 HIS B C     1 
ATOM   6829  O  O     . HIS B 1 355 ? -14.185 45.387  -39.866  1.00 52.75  ? 355 HIS B O     1 
ATOM   6830  C  CB    . HIS B 1 355 ? -14.679 45.744  -36.773  1.00 42.42  ? 355 HIS B CB    1 
ATOM   6831  C  CG    . HIS B 1 355 ? -15.670 46.123  -35.726  1.00 41.92  ? 355 HIS B CG    1 
ATOM   6832  N  ND1   . HIS B 1 355 ? -15.319 46.560  -34.462  1.00 41.74  ? 355 HIS B ND1   1 
ATOM   6833  C  CD2   . HIS B 1 355 ? -17.012 46.102  -35.760  1.00 39.05  ? 355 HIS B CD2   1 
ATOM   6834  C  CE1   . HIS B 1 355 ? -16.422 46.786  -33.763  1.00 44.72  ? 355 HIS B CE1   1 
ATOM   6835  N  NE2   . HIS B 1 355 ? -17.468 46.528  -34.529  1.00 47.88  ? 355 HIS B NE2   1 
ATOM   6836  N  N     . LYS B 1 356 ? -12.404 46.522  -39.025  1.00 43.67  ? 356 LYS B N     1 
ATOM   6837  C  CA    . LYS B 1 356 ? -11.416 46.039  -39.970  1.00 49.77  ? 356 LYS B CA    1 
ATOM   6838  C  C     . LYS B 1 356 ? -10.918 44.657  -39.551  1.00 46.78  ? 356 LYS B C     1 
ATOM   6839  O  O     . LYS B 1 356 ? -10.430 43.889  -40.371  1.00 49.82  ? 356 LYS B O     1 
ATOM   6840  C  CB    . LYS B 1 356 ? -10.209 46.985  -40.056  1.00 54.13  ? 356 LYS B CB    1 
ATOM   6841  C  CG    . LYS B 1 356 ? -10.382 48.260  -40.880  1.00 60.36  ? 356 LYS B CG    1 
ATOM   6842  C  CD    . LYS B 1 356 ? -9.137  48.553  -41.753  1.00 68.61  ? 356 LYS B CD    1 
ATOM   6843  C  CE    . LYS B 1 356 ? -8.947  49.995  -42.194  1.00 77.19  ? 356 LYS B CE    1 
ATOM   6844  N  NZ    . LYS B 1 356 ? -10.194 50.635  -42.679  1.00 83.66  ? 356 LYS B NZ    1 
ATOM   6845  N  N     . VAL B 1 357 ? -10.985 44.354  -38.259  1.00 43.28  ? 357 VAL B N     1 
ATOM   6846  C  CA    . VAL B 1 357 ? -10.709 43.011  -37.794  1.00 40.78  ? 357 VAL B CA    1 
ATOM   6847  C  C     . VAL B 1 357 ? -12.023 42.456  -37.258  1.00 42.27  ? 357 VAL B C     1 
ATOM   6848  O  O     . VAL B 1 357 ? -12.589 42.980  -36.298  1.00 39.86  ? 357 VAL B O     1 
ATOM   6849  C  CB    . VAL B 1 357 ? -9.576  43.007  -36.752  1.00 43.36  ? 357 VAL B CB    1 
ATOM   6850  C  CG1   . VAL B 1 357 ? -9.307  41.609  -36.223  1.00 41.39  ? 357 VAL B CG1   1 
ATOM   6851  C  CG2   . VAL B 1 357 ? -8.290  43.626  -37.314  1.00 43.48  ? 357 VAL B CG2   1 
ATOM   6852  N  N     . ASP B 1 358 ? -12.491 41.368  -37.882  1.00 44.49  ? 358 ASP B N     1 
ATOM   6853  C  CA    . ASP B 1 358 ? -13.914 41.061  -37.902  1.00 45.27  ? 358 ASP B CA    1 
ATOM   6854  C  C     . ASP B 1 358 ? -14.166 39.607  -38.303  1.00 43.33  ? 358 ASP B C     1 
ATOM   6855  O  O     . ASP B 1 358 ? -13.489 39.092  -39.174  1.00 45.29  ? 358 ASP B O     1 
ATOM   6856  C  CB    . ASP B 1 358 ? -14.600 41.974  -38.911  1.00 40.50  ? 358 ASP B CB    1 
ATOM   6857  C  CG    . ASP B 1 358 ? -16.108 41.839  -38.891  1.00 44.58  ? 358 ASP B CG    1 
ATOM   6858  O  OD1   . ASP B 1 358 ? -16.726 42.356  -37.928  1.00 45.42  ? 358 ASP B OD1   1 
ATOM   6859  O  OD2   . ASP B 1 358 ? -16.643 41.184  -39.824  1.00 46.56  ? 358 ASP B OD2   1 
ATOM   6860  N  N     . LEU B 1 359 ? -15.194 38.980  -37.732  1.00 40.41  ? 359 LEU B N     1 
ATOM   6861  C  CA    . LEU B 1 359 ? -15.497 37.596  -38.053  1.00 44.35  ? 359 LEU B CA    1 
ATOM   6862  C  C     . LEU B 1 359 ? -15.701 37.380  -39.557  1.00 38.74  ? 359 LEU B C     1 
ATOM   6863  O  O     . LEU B 1 359 ? -15.164 36.450  -40.128  1.00 40.46  ? 359 LEU B O     1 
ATOM   6864  C  CB    . LEU B 1 359 ? -16.760 37.148  -37.317  1.00 46.70  ? 359 LEU B CB    1 
ATOM   6865  C  CG    . LEU B 1 359 ? -17.316 35.822  -37.840  1.00 53.48  ? 359 LEU B CG    1 
ATOM   6866  C  CD1   . LEU B 1 359 ? -16.498 34.670  -37.283  1.00 50.00  ? 359 LEU B CD1   1 
ATOM   6867  C  CD2   . LEU B 1 359 ? -18.789 35.672  -37.533  1.00 58.66  ? 359 LEU B CD2   1 
ATOM   6868  N  N     . LEU B 1 360 ? -16.534 38.186  -40.198  1.00 39.11  ? 360 LEU B N     1 
ATOM   6869  C  CA    . LEU B 1 360 ? -16.817 37.961  -41.600  1.00 38.77  ? 360 LEU B CA    1 
ATOM   6870  C  C     . LEU B 1 360 ? -15.562 38.176  -42.437  1.00 41.72  ? 360 LEU B C     1 
ATOM   6871  O  O     . LEU B 1 360 ? -15.318 37.423  -43.380  1.00 40.86  ? 360 LEU B O     1 
ATOM   6872  C  CB    . LEU B 1 360 ? -17.959 38.864  -42.088  1.00 40.69  ? 360 LEU B CB    1 
ATOM   6873  C  CG    . LEU B 1 360 ? -18.264 38.755  -43.588  1.00 43.29  ? 360 LEU B CG    1 
ATOM   6874  C  CD1   . LEU B 1 360 ? -18.544 37.311  -43.994  1.00 45.23  ? 360 LEU B CD1   1 
ATOM   6875  C  CD2   . LEU B 1 360 ? -19.443 39.641  -43.973  1.00 38.87  ? 360 LEU B CD2   1 
ATOM   6876  N  N     . LEU B 1 361 ? -14.752 39.194  -42.130  1.00 42.75  ? 361 LEU B N     1 
ATOM   6877  C  CA    . LEU B 1 361 ? -13.590 39.416  -42.983  1.00 43.87  ? 361 LEU B CA    1 
ATOM   6878  C  C     . LEU B 1 361 ? -12.607 38.260  -42.822  1.00 41.45  ? 361 LEU B C     1 
ATOM   6879  O  O     . LEU B 1 361 ? -11.977 37.870  -43.804  1.00 44.04  ? 361 LEU B O     1 
ATOM   6880  C  CB    . LEU B 1 361 ? -12.950 40.776  -42.713  1.00 42.40  ? 361 LEU B CB    1 
ATOM   6881  C  CG    . LEU B 1 361 ? -13.896 41.962  -42.910  1.00 47.96  ? 361 LEU B CG    1 
ATOM   6882  C  CD1   . LEU B 1 361 ? -13.179 43.276  -42.650  1.00 50.57  ? 361 LEU B CD1   1 
ATOM   6883  C  CD2   . LEU B 1 361 ? -14.513 41.959  -44.301  1.00 46.54  ? 361 LEU B CD2   1 
ATOM   6884  N  N     . HIS B 1 362 ? -12.501 37.688  -41.616  1.00 43.45  ? 362 HIS B N     1 
ATOM   6885  C  CA    . HIS B 1 362 ? -11.753 36.443  -41.445  1.00 47.87  ? 362 HIS B CA    1 
ATOM   6886  C  C     . HIS B 1 362 ? -12.392 35.308  -42.262  1.00 40.79  ? 362 HIS B C     1 
ATOM   6887  O  O     . HIS B 1 362 ? -11.722 34.671  -43.050  1.00 39.99  ? 362 HIS B O     1 
ATOM   6888  C  CB    . HIS B 1 362 ? -11.582 36.050  -39.968  1.00 53.51  ? 362 HIS B CB    1 
ATOM   6889  C  CG    . HIS B 1 362 ? -11.269 34.585  -39.732  1.00 69.30  ? 362 HIS B CG    1 
ATOM   6890  N  ND1   . HIS B 1 362 ? -10.224 33.904  -40.327  1.00 69.91  ? 362 HIS B ND1   1 
ATOM   6891  C  CD2   . HIS B 1 362 ? -11.890 33.666  -38.947  1.00 74.32  ? 362 HIS B CD2   1 
ATOM   6892  C  CE1   . HIS B 1 362 ? -10.220 32.636  -39.922  1.00 69.25  ? 362 HIS B CE1   1 
ATOM   6893  N  NE2   . HIS B 1 362 ? -11.220 32.469  -39.076  1.00 72.36  ? 362 HIS B NE2   1 
ATOM   6894  N  N     . ARG B 1 363 ? -13.692 35.059  -42.105  1.00 40.66  ? 363 ARG B N     1 
ATOM   6895  C  CA    . ARG B 1 363 ? -14.301 33.868  -42.680  1.00 43.27  ? 363 ARG B CA    1 
ATOM   6896  C  C     . ARG B 1 363 ? -14.396 33.985  -44.206  1.00 41.53  ? 363 ARG B C     1 
ATOM   6897  O  O     . ARG B 1 363 ? -14.329 32.981  -44.913  1.00 38.55  ? 363 ARG B O     1 
ATOM   6898  C  CB    . ARG B 1 363 ? -15.597 33.567  -41.918  1.00 45.60  ? 363 ARG B CB    1 
ATOM   6899  C  CG    . ARG B 1 363 ? -15.326 33.163  -40.476  1.00 46.58  ? 363 ARG B CG    1 
ATOM   6900  C  CD    . ARG B 1 363 ? -16.211 32.081  -39.907  1.00 49.77  ? 363 ARG B CD    1 
ATOM   6901  N  NE    . ARG B 1 363 ? -16.053 30.807  -40.593  1.00 53.19  ? 363 ARG B NE    1 
ATOM   6902  C  CZ    . ARG B 1 363 ? -15.109 29.903  -40.342  1.00 55.15  ? 363 ARG B CZ    1 
ATOM   6903  N  NH1   . ARG B 1 363 ? -14.164 30.141  -39.447  1.00 54.02  ? 363 ARG B NH1   1 
ATOM   6904  N  NH2   . ARG B 1 363 ? -15.114 28.753  -41.004  1.00 53.64  ? 363 ARG B NH2   1 
ATOM   6905  N  N     . ALA B 1 364 ? -14.466 35.218  -44.725  1.00 39.91  ? 364 ALA B N     1 
ATOM   6906  C  CA    . ALA B 1 364 ? -14.403 35.461  -46.159  1.00 40.75  ? 364 ALA B CA    1 
ATOM   6907  C  C     . ALA B 1 364 ? -13.153 34.836  -46.792  1.00 44.16  ? 364 ALA B C     1 
ATOM   6908  O  O     . ALA B 1 364 ? -13.165 34.506  -47.983  1.00 37.87  ? 364 ALA B O     1 
ATOM   6909  C  CB    . ALA B 1 364 ? -14.473 36.943  -46.457  1.00 39.22  ? 364 ALA B CB    1 
ATOM   6910  N  N     . GLU B 1 365 ? -12.054 34.730  -46.029  1.00 43.41  ? 365 GLU B N     1 
ATOM   6911  C  CA    . GLU B 1 365 ? -10.837 34.123  -46.543  1.00 43.16  ? 365 GLU B CA    1 
ATOM   6912  C  C     . GLU B 1 365 ? -10.982 32.598  -46.527  1.00 42.77  ? 365 GLU B C     1 
ATOM   6913  O  O     . GLU B 1 365 ? -10.598 31.923  -47.482  1.00 38.78  ? 365 GLU B O     1 
ATOM   6914  C  CB    . GLU B 1 365 ? -9.624  34.573  -45.722  1.00 49.29  ? 365 GLU B CB    1 
ATOM   6915  C  CG    . GLU B 1 365 ? -9.305  36.066  -45.841  1.00 59.66  ? 365 GLU B CG    1 
ATOM   6916  C  CD    . GLU B 1 365 ? -9.059  36.581  -47.257  1.00 73.47  ? 365 GLU B CD    1 
ATOM   6917  O  OE1   . GLU B 1 365 ? -8.070  36.149  -47.898  1.00 76.39  ? 365 GLU B OE1   1 
ATOM   6918  O  OE2   . GLU B 1 365 ? -9.864  37.417  -47.733  1.00 92.28  ? 365 GLU B OE2   1 
ATOM   6919  N  N     . THR B 1 366 ? -11.547 32.054  -45.444  1.00 40.49  ? 366 THR B N     1 
ATOM   6920  C  CA    . THR B 1 366 ? -11.621 30.609  -45.302  1.00 45.62  ? 366 THR B CA    1 
ATOM   6921  C  C     . THR B 1 366 ? -12.560 30.047  -46.376  1.00 41.21  ? 366 THR B C     1 
ATOM   6922  O  O     . THR B 1 366 ? -12.308 28.994  -46.948  1.00 40.34  ? 366 THR B O     1 
ATOM   6923  C  CB    . THR B 1 366 ? -12.035 30.221  -43.874  1.00 44.82  ? 366 THR B CB    1 
ATOM   6924  O  OG1   . THR B 1 366 ? -11.389 31.093  -42.954  1.00 45.95  ? 366 THR B OG1   1 
ATOM   6925  C  CG2   . THR B 1 366 ? -11.683 28.794  -43.520  1.00 41.49  ? 366 THR B CG2   1 
ATOM   6926  N  N     . MET B 1 367 ? -13.655 30.760  -46.643  1.00 36.89  ? 367 MET B N     1 
ATOM   6927  C  CA    . MET B 1 367 ? -14.697 30.250  -47.508  1.00 36.57  ? 367 MET B CA    1 
ATOM   6928  C  C     . MET B 1 367 ? -14.287 30.382  -48.989  1.00 40.29  ? 367 MET B C     1 
ATOM   6929  O  O     . MET B 1 367 ? -15.043 29.985  -49.892  1.00 39.79  ? 367 MET B O     1 
ATOM   6930  C  CB    . MET B 1 367 ? -16.006 30.982  -47.204  1.00 34.48  ? 367 MET B CB    1 
ATOM   6931  C  CG    . MET B 1 367 ? -16.609 30.596  -45.861  1.00 34.02  ? 367 MET B CG    1 
ATOM   6932  S  SD    . MET B 1 367 ? -18.243 31.329  -45.512  1.00 37.89  ? 367 MET B SD    1 
ATOM   6933  C  CE    . MET B 1 367 ? -17.851 33.074  -45.643  1.00 38.73  ? 367 MET B CE    1 
ATOM   6934  N  N     . LYS B 1 368 ? -13.069 30.893  -49.253  1.00 39.56  ? 368 LYS B N     1 
ATOM   6935  C  CA    . LYS B 1 368 ? -12.478 30.835  -50.586  1.00 42.02  ? 368 LYS B CA    1 
ATOM   6936  C  C     . LYS B 1 368 ? -11.151 30.087  -50.559  1.00 39.30  ? 368 LYS B C     1 
ATOM   6937  O  O     . LYS B 1 368 ? -10.391 30.119  -51.526  1.00 40.79  ? 368 LYS B O     1 
ATOM   6938  C  CB    . LYS B 1 368 ? -12.326 32.230  -51.205  1.00 51.76  ? 368 LYS B CB    1 
ATOM   6939  C  CG    . LYS B 1 368 ? -11.051 32.995  -50.886  1.00 57.88  ? 368 LYS B CG    1 
ATOM   6940  C  CD    . LYS B 1 368 ? -10.813 34.186  -51.785  1.00 61.19  ? 368 LYS B CD    1 
ATOM   6941  C  CE    . LYS B 1 368 ? -11.063 35.502  -51.090  1.00 64.34  ? 368 LYS B CE    1 
ATOM   6942  N  NZ    . LYS B 1 368 ? -10.442 36.616  -51.845  1.00 67.32  ? 368 LYS B NZ    1 
ATOM   6943  N  N     . GLY B 1 369 ? -10.907 29.356  -49.478  1.00 36.34  ? 369 GLY B N     1 
ATOM   6944  C  CA    . GLY B 1 369 ? -9.840  28.384  -49.439  1.00 35.85  ? 369 GLY B CA    1 
ATOM   6945  C  C     . GLY B 1 369 ? -8.475  29.007  -49.158  1.00 37.67  ? 369 GLY B C     1 
ATOM   6946  O  O     . GLY B 1 369 ? -7.459  28.423  -49.516  1.00 39.40  ? 369 GLY B O     1 
ATOM   6947  N  N     . VAL B 1 370 ? -8.446  30.162  -48.488  1.00 38.91  ? 370 VAL B N     1 
ATOM   6948  C  CA    . VAL B 1 370 ? -7.186  30.756  -48.073  1.00 37.39  ? 370 VAL B CA    1 
ATOM   6949  C  C     . VAL B 1 370 ? -6.825  30.224  -46.691  1.00 39.16  ? 370 VAL B C     1 
ATOM   6950  O  O     . VAL B 1 370 ? -7.530  30.469  -45.722  1.00 40.51  ? 370 VAL B O     1 
ATOM   6951  C  CB    . VAL B 1 370 ? -7.239  32.295  -48.097  1.00 41.40  ? 370 VAL B CB    1 
ATOM   6952  C  CG1   . VAL B 1 370 ? -5.919  32.911  -47.646  1.00 38.45  ? 370 VAL B CG1   1 
ATOM   6953  C  CG2   . VAL B 1 370 ? -7.651  32.812  -49.478  1.00 41.39  ? 370 VAL B CG2   1 
ATOM   6954  N  N     . PRO B 1 371 ? -5.667  29.545  -46.541  1.00 42.28  ? 371 PRO B N     1 
ATOM   6955  C  CA    . PRO B 1 371 ? -5.289  28.929  -45.269  1.00 45.75  ? 371 PRO B CA    1 
ATOM   6956  C  C     . PRO B 1 371 ? -4.832  30.021  -44.312  1.00 45.89  ? 371 PRO B C     1 
ATOM   6957  O  O     . PRO B 1 371 ? -4.031  30.858  -44.698  1.00 44.04  ? 371 PRO B O     1 
ATOM   6958  C  CB    . PRO B 1 371 ? -4.148  27.966  -45.652  1.00 44.11  ? 371 PRO B CB    1 
ATOM   6959  C  CG    . PRO B 1 371 ? -3.505  28.643  -46.858  1.00 41.03  ? 371 PRO B CG    1 
ATOM   6960  C  CD    . PRO B 1 371 ? -4.635  29.357  -47.570  1.00 40.47  ? 371 PRO B CD    1 
ATOM   6961  N  N     . LYS B 1 372 ? -5.365  30.000  -43.091  1.00 41.30  ? 372 LYS B N     1 
ATOM   6962  C  CA    . LYS B 1 372 ? -5.006  30.955  -42.061  1.00 48.75  ? 372 LYS B CA    1 
ATOM   6963  C  C     . LYS B 1 372 ? -4.818  30.218  -40.744  1.00 48.18  ? 372 LYS B C     1 
ATOM   6964  O  O     . LYS B 1 372 ? -5.054  29.019  -40.659  1.00 46.09  ? 372 LYS B O     1 
ATOM   6965  C  CB    . LYS B 1 372 ? -6.076  32.041  -41.969  1.00 52.17  ? 372 LYS B CB    1 
ATOM   6966  C  CG    . LYS B 1 372 ? -5.925  33.155  -42.996  1.00 65.53  ? 372 LYS B CG    1 
ATOM   6967  C  CD    . LYS B 1 372 ? -7.250  33.723  -43.473  1.00 71.96  ? 372 LYS B CD    1 
ATOM   6968  C  CE    . LYS B 1 372 ? -8.180  34.171  -42.361  1.00 80.51  ? 372 LYS B CE    1 
ATOM   6969  N  NZ    . LYS B 1 372 ? -7.863  35.534  -41.861  1.00 81.89  ? 372 LYS B NZ    1 
ATOM   6970  N  N     . LEU B 1 373 ? -4.321  30.943  -39.744  1.00 51.18  ? 373 LEU B N     1 
ATOM   6971  C  CA    . LEU B 1 373 ? -4.142  30.395  -38.413  1.00 52.74  ? 373 LEU B CA    1 
ATOM   6972  C  C     . LEU B 1 373 ? -5.069  31.098  -37.432  1.00 54.09  ? 373 LEU B C     1 
ATOM   6973  O  O     . LEU B 1 373 ? -5.062  30.758  -36.250  1.00 54.45  ? 373 LEU B O     1 
ATOM   6974  C  CB    . LEU B 1 373 ? -2.681  30.580  -37.988  1.00 54.58  ? 373 LEU B CB    1 
ATOM   6975  C  CG    . LEU B 1 373 ? -1.655  29.699  -38.701  1.00 55.54  ? 373 LEU B CG    1 
ATOM   6976  C  CD1   . LEU B 1 373 ? -0.251  30.001  -38.185  1.00 56.34  ? 373 LEU B CD1   1 
ATOM   6977  C  CD2   . LEU B 1 373 ? -1.972  28.211  -38.550  1.00 55.18  ? 373 LEU B CD2   1 
ATOM   6978  N  N     . THR B 1 374 ? -5.879  32.047  -37.923  1.00 51.28  ? 374 THR B N     1 
ATOM   6979  C  CA    . THR B 1 374 ? -6.500  33.010  -37.028  1.00 53.12  ? 374 THR B CA    1 
ATOM   6980  C  C     . THR B 1 374 ? -7.589  32.333  -36.193  1.00 54.07  ? 374 THR B C     1 
ATOM   6981  O  O     . THR B 1 374 ? -7.910  32.825  -35.113  1.00 53.04  ? 374 THR B O     1 
ATOM   6982  C  CB    . THR B 1 374 ? -7.032  34.251  -37.762  1.00 61.97  ? 374 THR B CB    1 
ATOM   6983  O  OG1   . THR B 1 374 ? -8.298  33.948  -38.331  1.00 74.59  ? 374 THR B OG1   1 
ATOM   6984  C  CG2   . THR B 1 374 ? -6.109  34.760  -38.848  1.00 61.05  ? 374 THR B CG2   1 
ATOM   6985  N  N     . GLU B 1 375 ? -8.134  31.197  -36.655  1.00 51.99  ? 375 GLU B N     1 
ATOM   6986  C  CA    . GLU B 1 375 ? -9.123  30.473  -35.868  1.00 51.70  ? 375 GLU B CA    1 
ATOM   6987  C  C     . GLU B 1 375 ? -8.579  30.079  -34.491  1.00 48.30  ? 375 GLU B C     1 
ATOM   6988  O  O     . GLU B 1 375 ? -9.328  30.061  -33.521  1.00 47.94  ? 375 GLU B O     1 
ATOM   6989  C  CB    . GLU B 1 375 ? -9.597  29.197  -36.560  1.00 49.01  ? 375 GLU B CB    1 
ATOM   6990  C  CG    . GLU B 1 375 ? -10.904 28.704  -35.975  1.00 49.01  ? 375 GLU B CG    1 
ATOM   6991  C  CD    . GLU B 1 375 ? -12.099 29.557  -36.365  1.00 51.01  ? 375 GLU B CD    1 
ATOM   6992  O  OE1   . GLU B 1 375 ? -11.998 30.348  -37.340  1.00 58.48  ? 375 GLU B OE1   1 
ATOM   6993  O  OE2   . GLU B 1 375 ? -13.118 29.442  -35.674  1.00 59.22  ? 375 GLU B OE2   1 
ATOM   6994  N  N     . PHE B 1 376 ? -7.276  29.791  -34.392  1.00 47.14  ? 376 PHE B N     1 
ATOM   6995  C  CA    . PHE B 1 376 ? -6.668  29.440  -33.116  1.00 48.13  ? 376 PHE B CA    1 
ATOM   6996  C  C     . PHE B 1 376 ? -6.879  30.529  -32.059  1.00 46.69  ? 376 PHE B C     1 
ATOM   6997  O  O     . PHE B 1 376 ? -6.705  30.290  -30.869  1.00 47.44  ? 376 PHE B O     1 
ATOM   6998  C  CB    . PHE B 1 376 ? -5.169  29.170  -33.271  1.00 48.70  ? 376 PHE B CB    1 
ATOM   6999  C  CG    . PHE B 1 376 ? -4.798  27.755  -33.627  1.00 59.74  ? 376 PHE B CG    1 
ATOM   7000  C  CD1   . PHE B 1 376 ? -4.868  27.303  -34.936  1.00 64.00  ? 376 PHE B CD1   1 
ATOM   7001  C  CD2   . PHE B 1 376 ? -4.367  26.868  -32.650  1.00 63.94  ? 376 PHE B CD2   1 
ATOM   7002  C  CE1   . PHE B 1 376 ? -4.499  26.004  -35.254  1.00 62.82  ? 376 PHE B CE1   1 
ATOM   7003  C  CE2   . PHE B 1 376 ? -4.014  25.564  -32.973  1.00 62.89  ? 376 PHE B CE2   1 
ATOM   7004  C  CZ    . PHE B 1 376 ? -4.086  25.132  -34.274  1.00 63.27  ? 376 PHE B CZ    1 
ATOM   7005  N  N     . ASN B 1 377 ? -7.232  31.741  -32.472  1.00 46.61  ? 377 ASN B N     1 
ATOM   7006  C  CA    . ASN B 1 377 ? -7.493  32.810  -31.524  1.00 45.72  ? 377 ASN B CA    1 
ATOM   7007  C  C     . ASN B 1 377 ? -8.532  32.438  -30.465  1.00 48.22  ? 377 ASN B C     1 
ATOM   7008  O  O     . ASN B 1 377 ? -8.484  32.969  -29.358  1.00 42.15  ? 377 ASN B O     1 
ATOM   7009  C  CB    . ASN B 1 377 ? -8.019  34.057  -32.236  1.00 51.70  ? 377 ASN B CB    1 
ATOM   7010  C  CG    . ASN B 1 377 ? -6.935  34.813  -32.966  1.00 48.22  ? 377 ASN B CG    1 
ATOM   7011  O  OD1   . ASN B 1 377 ? -5.761  34.657  -32.673  1.00 48.92  ? 377 ASN B OD1   1 
ATOM   7012  N  ND2   . ASN B 1 377 ? -7.326  35.647  -33.910  1.00 49.38  ? 377 ASN B ND2   1 
ATOM   7013  N  N     . PHE B 1 378 ? -9.521  31.584  -30.776  1.00 44.54  ? 378 PHE B N     1 
ATOM   7014  C  CA    . PHE B 1 378 ? -10.543 31.338  -29.763  1.00 40.87  ? 378 PHE B CA    1 
ATOM   7015  C  C     . PHE B 1 378 ? -9.885  30.662  -28.559  1.00 40.70  ? 378 PHE B C     1 
ATOM   7016  O  O     . PHE B 1 378 ? -10.433 30.682  -27.464  1.00 43.29  ? 378 PHE B O     1 
ATOM   7017  C  CB    . PHE B 1 378 ? -11.761 30.611  -30.341  1.00 43.41  ? 378 PHE B CB    1 
ATOM   7018  C  CG    . PHE B 1 378 ? -11.584 29.161  -30.724  1.00 42.33  ? 378 PHE B CG    1 
ATOM   7019  C  CD1   . PHE B 1 378 ? -11.318 28.185  -29.765  1.00 40.95  ? 378 PHE B CD1   1 
ATOM   7020  C  CD2   . PHE B 1 378 ? -11.772 28.756  -32.036  1.00 42.44  ? 378 PHE B CD2   1 
ATOM   7021  C  CE1   . PHE B 1 378 ? -11.208 26.845  -30.116  1.00 43.89  ? 378 PHE B CE1   1 
ATOM   7022  C  CE2   . PHE B 1 378 ? -11.657 27.410  -32.386  1.00 45.10  ? 378 PHE B CE2   1 
ATOM   7023  C  CZ    . PHE B 1 378 ? -11.373 26.459  -31.430  1.00 43.16  ? 378 PHE B CZ    1 
ATOM   7024  N  N     . LEU B 1 379 ? -8.687  30.090  -28.742  1.00 37.37  ? 379 LEU B N     1 
ATOM   7025  C  CA    . LEU B 1 379 ? -8.003  29.463  -27.625  1.00 43.29  ? 379 LEU B CA    1 
ATOM   7026  C  C     . LEU B 1 379 ? -7.562  30.489  -26.569  1.00 44.99  ? 379 LEU B C     1 
ATOM   7027  O  O     . LEU B 1 379 ? -7.223  30.093  -25.454  1.00 43.55  ? 379 LEU B O     1 
ATOM   7028  C  CB    . LEU B 1 379 ? -6.805  28.691  -28.172  1.00 46.09  ? 379 LEU B CB    1 
ATOM   7029  C  CG    . LEU B 1 379 ? -7.118  27.456  -29.018  1.00 47.77  ? 379 LEU B CG    1 
ATOM   7030  C  CD1   . LEU B 1 379 ? -5.831  26.855  -29.549  1.00 46.70  ? 379 LEU B CD1   1 
ATOM   7031  C  CD2   . LEU B 1 379 ? -7.871  26.415  -28.215  1.00 49.23  ? 379 LEU B CD2   1 
ATOM   7032  N  N     . ASN B 1 380 ? -7.584  31.795  -26.907  1.00 41.22  ? 380 ASN B N     1 
ATOM   7033  C  CA    . ASN B 1 380 ? -7.220  32.859  -25.978  1.00 43.21  ? 380 ASN B CA    1 
ATOM   7034  C  C     . ASN B 1 380 ? -8.386  33.346  -25.133  1.00 45.35  ? 380 ASN B C     1 
ATOM   7035  O  O     . ASN B 1 380 ? -8.217  34.270  -24.347  1.00 46.92  ? 380 ASN B O     1 
ATOM   7036  C  CB    . ASN B 1 380 ? -6.653  34.067  -26.728  1.00 44.57  ? 380 ASN B CB    1 
ATOM   7037  C  CG    . ASN B 1 380 ? -5.291  33.735  -27.285  1.00 48.63  ? 380 ASN B CG    1 
ATOM   7038  O  OD1   . ASN B 1 380 ? -4.582  32.930  -26.696  1.00 51.84  ? 380 ASN B OD1   1 
ATOM   7039  N  ND2   . ASN B 1 380 ? -4.953  34.261  -28.443  1.00 50.77  ? 380 ASN B ND2   1 
ATOM   7040  N  N     . TRP B 1 381 ? -9.571  32.748  -25.309  1.00 42.35  ? 381 TRP B N     1 
ATOM   7041  C  CA    . TRP B 1 381 ? -10.770 33.290  -24.720  1.00 40.33  ? 381 TRP B CA    1 
ATOM   7042  C  C     . TRP B 1 381 ? -10.572 33.505  -23.226  1.00 42.57  ? 381 TRP B C     1 
ATOM   7043  O  O     . TRP B 1 381 ? -10.926 34.558  -22.705  1.00 42.12  ? 381 TRP B O     1 
ATOM   7044  C  CB    . TRP B 1 381 ? -11.975 32.384  -25.004  1.00 40.02  ? 381 TRP B CB    1 
ATOM   7045  C  CG    . TRP B 1 381 ? -13.195 32.851  -24.287  1.00 39.88  ? 381 TRP B CG    1 
ATOM   7046  C  CD1   . TRP B 1 381 ? -13.831 32.236  -23.245  1.00 40.74  ? 381 TRP B CD1   1 
ATOM   7047  C  CD2   . TRP B 1 381 ? -13.919 34.065  -24.550  1.00 39.54  ? 381 TRP B CD2   1 
ATOM   7048  N  NE1   . TRP B 1 381 ? -14.909 32.980  -22.855  1.00 41.07  ? 381 TRP B NE1   1 
ATOM   7049  C  CE2   . TRP B 1 381 ? -14.991 34.106  -23.637  1.00 38.33  ? 381 TRP B CE2   1 
ATOM   7050  C  CE3   . TRP B 1 381 ? -13.772 35.113  -25.468  1.00 39.02  ? 381 TRP B CE3   1 
ATOM   7051  C  CZ2   . TRP B 1 381 ? -15.878 35.185  -23.586  1.00 42.39  ? 381 TRP B CZ2   1 
ATOM   7052  C  CZ3   . TRP B 1 381 ? -14.647 36.177  -25.417  1.00 39.11  ? 381 TRP B CZ3   1 
ATOM   7053  C  CH2   . TRP B 1 381 ? -15.694 36.206  -24.494  1.00 39.66  ? 381 TRP B CH2   1 
ATOM   7054  N  N     . ASP B 1 382 ? -10.086 32.478  -22.525  1.00 49.21  ? 382 ASP B N     1 
ATOM   7055  C  CA    . ASP B 1 382 ? -9.967  32.554  -21.074  1.00 51.38  ? 382 ASP B CA    1 
ATOM   7056  C  C     . ASP B 1 382 ? -8.492  32.648  -20.679  1.00 54.58  ? 382 ASP B C     1 
ATOM   7057  O  O     . ASP B 1 382 ? -8.080  32.070  -19.676  1.00 49.09  ? 382 ASP B O     1 
ATOM   7058  C  CB    . ASP B 1 382 ? -10.629 31.359  -20.378  1.00 54.60  ? 382 ASP B CB    1 
ATOM   7059  C  CG    . ASP B 1 382 ? -10.785 31.574  -18.879  1.00 57.54  ? 382 ASP B CG    1 
ATOM   7060  O  OD1   . ASP B 1 382 ? -10.751 32.738  -18.461  1.00 61.11  ? 382 ASP B OD1   1 
ATOM   7061  O  OD2   . ASP B 1 382 ? -10.905 30.580  -18.137  1.00 57.46  ? 382 ASP B OD2   1 
ATOM   7062  N  N     . GLY B 1 383 ? -7.700  33.353  -21.498  1.00 48.02  ? 383 GLY B N     1 
ATOM   7063  C  CA    . GLY B 1 383 ? -6.324  33.672  -21.168  1.00 48.28  ? 383 GLY B CA    1 
ATOM   7064  C  C     . GLY B 1 383 ? -5.336  32.707  -21.806  1.00 50.64  ? 383 GLY B C     1 
ATOM   7065  O  O     . GLY B 1 383 ? -4.136  32.869  -21.639  1.00 58.17  ? 383 GLY B O     1 
ATOM   7066  N  N     . GLY B 1 384 ? -5.824  31.686  -22.517  1.00 53.48  ? 384 GLY B N     1 
ATOM   7067  C  CA    . GLY B 1 384 ? -4.926  30.741  -23.166  1.00 53.96  ? 384 GLY B CA    1 
ATOM   7068  C  C     . GLY B 1 384 ? -5.084  29.319  -22.641  1.00 48.72  ? 384 GLY B C     1 
ATOM   7069  O  O     . GLY B 1 384 ? -4.932  29.062  -21.454  1.00 48.53  ? 384 GLY B O     1 
ATOM   7070  N  N     . GLY B 1 385 ? -5.394  28.388  -23.549  1.00 45.15  ? 385 GLY B N     1 
ATOM   7071  C  CA    . GLY B 1 385 ? -5.541  26.996  -23.170  1.00 45.55  ? 385 GLY B CA    1 
ATOM   7072  C  C     . GLY B 1 385 ? -5.640  26.094  -24.396  1.00 48.89  ? 385 GLY B C     1 
ATOM   7073  O  O     . GLY B 1 385 ? -5.325  26.507  -25.511  1.00 48.60  ? 385 GLY B O     1 
ATOM   7074  N  N     . GLY B 1 386 ? -6.004  24.831  -24.169  1.00 49.57  ? 386 GLY B N     1 
ATOM   7075  C  CA    . GLY B 1 386 ? -6.237  23.914  -25.273  1.00 48.77  ? 386 GLY B CA    1 
ATOM   7076  C  C     . GLY B 1 386 ? -7.722  23.887  -25.626  1.00 46.10  ? 386 GLY B C     1 
ATOM   7077  O  O     . GLY B 1 386 ? -8.493  24.630  -25.029  1.00 42.76  ? 386 GLY B O     1 
ATOM   7078  N  N     . HIS B 1 387 ? -8.115  23.017  -26.571  1.00 42.58  ? 387 HIS B N     1 
ATOM   7079  C  CA    . HIS B 1 387 ? -9.521  22.813  -26.850  1.00 42.28  ? 387 HIS B CA    1 
ATOM   7080  C  C     . HIS B 1 387 ? -9.804  21.334  -27.086  1.00 44.64  ? 387 HIS B C     1 
ATOM   7081  O  O     . HIS B 1 387 ? -8.935  20.533  -27.407  1.00 41.57  ? 387 HIS B O     1 
ATOM   7082  C  CB    . HIS B 1 387 ? -10.050 23.673  -28.007  1.00 43.51  ? 387 HIS B CB    1 
ATOM   7083  C  CG    . HIS B 1 387 ? -9.582  23.384  -29.419  1.00 49.40  ? 387 HIS B CG    1 
ATOM   7084  N  ND1   . HIS B 1 387 ? -10.489 23.019  -30.395  1.00 48.84  ? 387 HIS B ND1   1 
ATOM   7085  C  CD2   . HIS B 1 387 ? -8.376  23.480  -30.047  1.00 53.63  ? 387 HIS B CD2   1 
ATOM   7086  C  CE1   . HIS B 1 387 ? -9.876  22.897  -31.580  1.00 53.90  ? 387 HIS B CE1   1 
ATOM   7087  N  NE2   . HIS B 1 387 ? -8.521  23.171  -31.433  1.00 55.26  ? 387 HIS B NE2   1 
ATOM   7088  N  N     . VAL B 1 388 ? -11.071 20.993  -26.896  1.00 45.27  ? 388 VAL B N     1 
ATOM   7089  C  CA    . VAL B 1 388 ? -11.570 19.741  -27.408  1.00 45.15  ? 388 VAL B CA    1 
ATOM   7090  C  C     . VAL B 1 388 ? -12.930 20.045  -28.038  1.00 37.84  ? 388 VAL B C     1 
ATOM   7091  O  O     . VAL B 1 388 ? -13.581 21.054  -27.739  1.00 42.86  ? 388 VAL B O     1 
ATOM   7092  C  CB    . VAL B 1 388 ? -11.558 18.688  -26.282  1.00 47.40  ? 388 VAL B CB    1 
ATOM   7093  C  CG1   . VAL B 1 388 ? -12.607 19.000  -25.227  1.00 47.33  ? 388 VAL B CG1   1 
ATOM   7094  C  CG2   . VAL B 1 388 ? -11.675 17.269  -26.817  1.00 53.25  ? 388 VAL B CG2   1 
ATOM   7095  N  N     . GLY B 1 389 ? -13.303 19.208  -28.987  1.00 37.00  ? 389 GLY B N     1 
ATOM   7096  C  CA    . GLY B 1 389 ? -14.511 19.416  -29.757  1.00 37.25  ? 389 GLY B CA    1 
ATOM   7097  C  C     . GLY B 1 389 ? -15.358 18.150  -29.780  1.00 42.95  ? 389 GLY B C     1 
ATOM   7098  O  O     . GLY B 1 389 ? -14.834 17.038  -29.763  1.00 37.13  ? 389 GLY B O     1 
ATOM   7099  N  N     . PHE B 1 390 ? -16.674 18.374  -29.764  1.00 45.06  ? 390 PHE B N     1 
ATOM   7100  C  CA    . PHE B 1 390 ? -17.657 17.327  -29.803  1.00 40.11  ? 390 PHE B CA    1 
ATOM   7101  C  C     . PHE B 1 390 ? -18.624 17.668  -30.934  1.00 43.05  ? 390 PHE B C     1 
ATOM   7102  O  O     . PHE B 1 390 ? -19.327 18.685  -30.886  1.00 38.65  ? 390 PHE B O     1 
ATOM   7103  C  CB    . PHE B 1 390 ? -18.314 17.200  -28.427  1.00 45.24  ? 390 PHE B CB    1 
ATOM   7104  C  CG    . PHE B 1 390 ? -19.338 16.091  -28.353  1.00 43.19  ? 390 PHE B CG    1 
ATOM   7105  C  CD1   . PHE B 1 390 ? -19.000 14.793  -28.719  1.00 44.06  ? 390 PHE B CD1   1 
ATOM   7106  C  CD2   . PHE B 1 390 ? -20.638 16.352  -27.965  1.00 39.38  ? 390 PHE B CD2   1 
ATOM   7107  C  CE1   . PHE B 1 390 ? -19.951 13.781  -28.698  1.00 46.65  ? 390 PHE B CE1   1 
ATOM   7108  C  CE2   . PHE B 1 390 ? -21.583 15.339  -27.926  1.00 40.61  ? 390 PHE B CE2   1 
ATOM   7109  C  CZ    . PHE B 1 390 ? -21.244 14.063  -28.314  1.00 43.45  ? 390 PHE B CZ    1 
ATOM   7110  N  N     . SER B 1 391 ? -18.629 16.834  -31.978  1.00 37.57  ? 391 SER B N     1 
ATOM   7111  C  CA    . SER B 1 391 ? -19.267 17.229  -33.227  1.00 38.12  ? 391 SER B CA    1 
ATOM   7112  C  C     . SER B 1 391 ? -20.246 16.159  -33.715  1.00 39.12  ? 391 SER B C     1 
ATOM   7113  O  O     . SER B 1 391 ? -20.178 15.681  -34.852  1.00 37.22  ? 391 SER B O     1 
ATOM   7114  C  CB    . SER B 1 391 ? -18.219 17.563  -34.234  1.00 37.37  ? 391 SER B CB    1 
ATOM   7115  O  OG    . SER B 1 391 ? -17.325 16.476  -34.387  1.00 41.23  ? 391 SER B OG    1 
ATOM   7116  N  N     . PRO B 1 392 ? -21.187 15.710  -32.856  1.00 40.00  ? 392 PRO B N     1 
ATOM   7117  C  CA    . PRO B 1 392 ? -22.066 14.602  -33.227  1.00 39.28  ? 392 PRO B CA    1 
ATOM   7118  C  C     . PRO B 1 392 ? -22.974 14.986  -34.387  1.00 38.51  ? 392 PRO B C     1 
ATOM   7119  O  O     . PRO B 1 392 ? -23.227 16.176  -34.607  1.00 35.41  ? 392 PRO B O     1 
ATOM   7120  C  CB    . PRO B 1 392 ? -22.856 14.356  -31.933  1.00 41.57  ? 392 PRO B CB    1 
ATOM   7121  C  CG    . PRO B 1 392 ? -22.847 15.718  -31.252  1.00 41.39  ? 392 PRO B CG    1 
ATOM   7122  C  CD    . PRO B 1 392 ? -21.439 16.205  -31.496  1.00 37.72  ? 392 PRO B CD    1 
ATOM   7123  N  N     . VAL B 1 393 ? -23.476 13.952  -35.079  1.00 37.94  ? 393 VAL B N     1 
ATOM   7124  C  CA    . VAL B 1 393 ? -24.379 14.059  -36.216  1.00 39.51  ? 393 VAL B CA    1 
ATOM   7125  C  C     . VAL B 1 393 ? -25.841 14.043  -35.758  1.00 34.94  ? 393 VAL B C     1 
ATOM   7126  O  O     . VAL B 1 393 ? -26.244 13.202  -34.959  1.00 35.26  ? 393 VAL B O     1 
ATOM   7127  C  CB    . VAL B 1 393 ? -24.152 12.873  -37.176  1.00 43.21  ? 393 VAL B CB    1 
ATOM   7128  C  CG1   . VAL B 1 393 ? -25.047 12.992  -38.380  1.00 44.32  ? 393 VAL B CG1   1 
ATOM   7129  C  CG2   . VAL B 1 393 ? -22.698 12.754  -37.607  1.00 41.19  ? 393 VAL B CG2   1 
ATOM   7130  N  N     . SER B 1 394 ? -26.673 14.868  -36.395  1.00 33.95  ? 394 SER B N     1 
ATOM   7131  C  CA    . SER B 1 394 ? -28.087 14.892  -36.078  1.00 36.45  ? 394 SER B CA    1 
ATOM   7132  C  C     . SER B 1 394 ? -28.867 15.298  -37.323  1.00 38.54  ? 394 SER B C     1 
ATOM   7133  O  O     . SER B 1 394 ? -28.279 15.767  -38.289  1.00 37.29  ? 394 SER B O     1 
ATOM   7134  C  CB    . SER B 1 394 ? -28.358 15.804  -34.868  1.00 39.66  ? 394 SER B CB    1 
ATOM   7135  O  OG    . SER B 1 394 ? -28.170 17.175  -35.188  1.00 39.65  ? 394 SER B OG    1 
ATOM   7136  N  N     . PRO B 1 395 ? -30.202 15.069  -37.385  1.00 36.66  ? 395 PRO B N     1 
ATOM   7137  C  CA    . PRO B 1 395 ? -31.019 15.626  -38.455  1.00 35.56  ? 395 PRO B CA    1 
ATOM   7138  C  C     . PRO B 1 395 ? -31.041 17.154  -38.444  1.00 36.53  ? 395 PRO B C     1 
ATOM   7139  O  O     . PRO B 1 395 ? -30.987 17.769  -37.390  1.00 40.79  ? 395 PRO B O     1 
ATOM   7140  C  CB    . PRO B 1 395 ? -32.438 15.082  -38.161  1.00 41.76  ? 395 PRO B CB    1 
ATOM   7141  C  CG    . PRO B 1 395 ? -32.223 13.900  -37.230  1.00 38.43  ? 395 PRO B CG    1 
ATOM   7142  C  CD    . PRO B 1 395 ? -30.964 14.229  -36.457  1.00 38.57  ? 395 PRO B CD    1 
ATOM   7143  N  N     . ILE B 1 396 ? -31.158 17.765  -39.625  1.00 38.25  ? 396 ILE B N     1 
ATOM   7144  C  CA    . ILE B 1 396 ? -31.315 19.206  -39.741  1.00 37.02  ? 396 ILE B CA    1 
ATOM   7145  C  C     . ILE B 1 396 ? -32.740 19.580  -39.336  1.00 36.94  ? 396 ILE B C     1 
ATOM   7146  O  O     . ILE B 1 396 ? -33.575 19.861  -40.177  1.00 36.53  ? 396 ILE B O     1 
ATOM   7147  C  CB    . ILE B 1 396 ? -30.967 19.709  -41.147  1.00 36.82  ? 396 ILE B CB    1 
ATOM   7148  C  CG1   . ILE B 1 396 ? -29.670 19.078  -41.660  1.00 40.71  ? 396 ILE B CG1   1 
ATOM   7149  C  CG2   . ILE B 1 396 ? -30.874 21.237  -41.129  1.00 38.75  ? 396 ILE B CG2   1 
ATOM   7150  C  CD1   . ILE B 1 396 ? -29.381 19.354  -43.113  1.00 40.44  ? 396 ILE B CD1   1 
ATOM   7151  N  N     . THR B 1 397 ? -32.967 19.623  -38.026  1.00 37.18  ? 397 THR B N     1 
ATOM   7152  C  CA    . THR B 1 397 ? -34.247 20.003  -37.453  1.00 48.29  ? 397 THR B CA    1 
ATOM   7153  C  C     . THR B 1 397 ? -34.028 21.122  -36.432  1.00 44.61  ? 397 THR B C     1 
ATOM   7154  O  O     . THR B 1 397 ? -33.034 21.116  -35.706  1.00 43.00  ? 397 THR B O     1 
ATOM   7155  C  CB    . THR B 1 397 ? -34.856 18.729  -36.857  1.00 46.64  ? 397 THR B CB    1 
ATOM   7156  O  OG1   . THR B 1 397 ? -35.398 17.971  -37.947  1.00 56.25  ? 397 THR B OG1   1 
ATOM   7157  C  CG2   . THR B 1 397 ? -35.903 18.978  -35.819  1.00 53.38  ? 397 THR B CG2   1 
ATOM   7158  N  N     . GLY B 1 398 ? -34.973 22.065  -36.373  1.00 43.63  ? 398 GLY B N     1 
ATOM   7159  C  CA    . GLY B 1 398 ? -35.032 23.043  -35.292  1.00 42.87  ? 398 GLY B CA    1 
ATOM   7160  C  C     . GLY B 1 398 ? -35.042 22.381  -33.908  1.00 42.58  ? 398 GLY B C     1 
ATOM   7161  O  O     . GLY B 1 398 ? -34.263 22.767  -33.035  1.00 39.60  ? 398 GLY B O     1 
ATOM   7162  N  N     . LYS B 1 399 ? -35.885 21.349  -33.737  1.00 43.52  ? 399 LYS B N     1 
ATOM   7163  C  CA    . LYS B 1 399 ? -35.952 20.581  -32.502  1.00 43.13  ? 399 LYS B CA    1 
ATOM   7164  C  C     . LYS B 1 399 ? -34.579 20.012  -32.155  1.00 40.28  ? 399 LYS B C     1 
ATOM   7165  O  O     . LYS B 1 399 ? -34.147 20.105  -31.007  1.00 45.04  ? 399 LYS B O     1 
ATOM   7166  C  CB    . LYS B 1 399 ? -37.009 19.471  -32.578  1.00 52.67  ? 399 LYS B CB    1 
ATOM   7167  C  CG    . LYS B 1 399 ? -37.031 18.481  -31.409  1.00 64.07  ? 399 LYS B CG    1 
ATOM   7168  C  CD    . LYS B 1 399 ? -37.830 17.187  -31.647  1.00 72.47  ? 399 LYS B CD    1 
ATOM   7169  C  CE    . LYS B 1 399 ? -37.123 16.174  -32.530  1.00 78.13  ? 399 LYS B CE    1 
ATOM   7170  N  NZ    . LYS B 1 399 ? -35.989 15.531  -31.823  1.00 81.16  ? 399 LYS B NZ    1 
ATOM   7171  N  N     . ASP B 1 400 ? -33.889 19.404  -33.121  1.00 40.21  ? 400 ASP B N     1 
ATOM   7172  C  CA    . ASP B 1 400 ? -32.634 18.748  -32.809  1.00 34.74  ? 400 ASP B CA    1 
ATOM   7173  C  C     . ASP B 1 400 ? -31.632 19.819  -32.381  1.00 33.97  ? 400 ASP B C     1 
ATOM   7174  O  O     . ASP B 1 400 ? -30.926 19.664  -31.390  1.00 39.38  ? 400 ASP B O     1 
ATOM   7175  C  CB    . ASP B 1 400 ? -32.157 17.898  -33.981  1.00 36.15  ? 400 ASP B CB    1 
ATOM   7176  C  CG    . ASP B 1 400 ? -32.937 16.603  -34.108  1.00 38.44  ? 400 ASP B CG    1 
ATOM   7177  O  OD1   . ASP B 1 400 ? -32.782 15.770  -33.226  1.00 41.93  ? 400 ASP B OD1   1 
ATOM   7178  O  OD2   . ASP B 1 400 ? -33.711 16.471  -35.070  1.00 44.07  ? 400 ASP B OD2   1 
ATOM   7179  N  N     . ALA B 1 401 ? -31.671 20.945  -33.085  1.00 36.33  ? 401 ALA B N     1 
ATOM   7180  C  CA    . ALA B 1 401 ? -30.727 22.027  -32.858  1.00 38.54  ? 401 ALA B CA    1 
ATOM   7181  C  C     . ALA B 1 401 ? -30.927 22.652  -31.479  1.00 36.88  ? 401 ALA B C     1 
ATOM   7182  O  O     . ALA B 1 401 ? -29.984 22.748  -30.712  1.00 39.16  ? 401 ALA B O     1 
ATOM   7183  C  CB    . ALA B 1 401 ? -30.869 23.051  -33.943  1.00 38.80  ? 401 ALA B CB    1 
ATOM   7184  N  N     . ILE B 1 402 ? -32.153 23.061  -31.154  1.00 40.68  ? 402 ILE B N     1 
ATOM   7185  C  CA    . ILE B 1 402 ? -32.355 23.781  -29.917  1.00 36.77  ? 402 ILE B CA    1 
ATOM   7186  C  C     . ILE B 1 402 ? -32.200 22.825  -28.745  1.00 41.68  ? 402 ILE B C     1 
ATOM   7187  O  O     . ILE B 1 402 ? -31.694 23.218  -27.700  1.00 41.76  ? 402 ILE B O     1 
ATOM   7188  C  CB    . ILE B 1 402 ? -33.693 24.536  -29.899  1.00 44.55  ? 402 ILE B CB    1 
ATOM   7189  C  CG1   . ILE B 1 402 ? -33.645 25.640  -28.831  1.00 49.39  ? 402 ILE B CG1   1 
ATOM   7190  C  CG2   . ILE B 1 402 ? -34.867 23.581  -29.736  1.00 42.14  ? 402 ILE B CG2   1 
ATOM   7191  C  CD1   . ILE B 1 402 ? -34.845 26.549  -28.796  1.00 49.20  ? 402 ILE B CD1   1 
ATOM   7192  N  N     . LYS B 1 403 ? -32.576 21.553  -28.925  1.00 40.52  ? 403 LYS B N     1 
ATOM   7193  C  CA    . LYS B 1 403 ? -32.348 20.607  -27.861  1.00 38.96  ? 403 LYS B CA    1 
ATOM   7194  C  C     . LYS B 1 403 ? -30.852 20.493  -27.556  1.00 38.02  ? 403 LYS B C     1 
ATOM   7195  O  O     . LYS B 1 403 ? -30.457 20.425  -26.390  1.00 37.76  ? 403 LYS B O     1 
ATOM   7196  C  CB    . LYS B 1 403 ? -32.900 19.237  -28.232  1.00 43.71  ? 403 LYS B CB    1 
ATOM   7197  C  CG    . LYS B 1 403 ? -32.764 18.202  -27.130  1.00 50.02  ? 403 LYS B CG    1 
ATOM   7198  C  CD    . LYS B 1 403 ? -32.737 16.791  -27.632  1.00 54.98  ? 403 LYS B CD    1 
ATOM   7199  C  CE    . LYS B 1 403 ? -34.059 16.346  -28.207  1.00 61.98  ? 403 LYS B CE    1 
ATOM   7200  N  NZ    . LYS B 1 403 ? -33.905 15.069  -28.952  1.00 69.51  ? 403 LYS B NZ    1 
ATOM   7201  N  N     . GLN B 1 404 ? -30.010 20.371  -28.593  1.00 35.32  ? 404 GLN B N     1 
ATOM   7202  C  CA    . GLN B 1 404 ? -28.591 20.176  -28.335  1.00 35.98  ? 404 GLN B CA    1 
ATOM   7203  C  C     . GLN B 1 404 ? -28.024 21.449  -27.707  1.00 35.27  ? 404 GLN B C     1 
ATOM   7204  O  O     . GLN B 1 404 ? -27.227 21.364  -26.794  1.00 38.12  ? 404 GLN B O     1 
ATOM   7205  C  CB    . GLN B 1 404 ? -27.865 19.721  -29.602  1.00 39.61  ? 404 GLN B CB    1 
ATOM   7206  C  CG    . GLN B 1 404 ? -28.124 18.244  -29.923  1.00 39.16  ? 404 GLN B CG    1 
ATOM   7207  C  CD    . GLN B 1 404 ? -27.565 17.896  -31.273  1.00 36.60  ? 404 GLN B CD    1 
ATOM   7208  O  OE1   . GLN B 1 404 ? -26.463 17.358  -31.374  1.00 41.35  ? 404 GLN B OE1   1 
ATOM   7209  N  NE2   . GLN B 1 404 ? -28.302 18.247  -32.321  1.00 35.78  ? 404 GLN B NE2   1 
ATOM   7210  N  N     . TYR B 1 405 ? -28.464 22.619  -28.181  1.00 35.20  ? 405 TYR B N     1 
ATOM   7211  C  CA    . TYR B 1 405 ? -28.002 23.876  -27.619  1.00 39.25  ? 405 TYR B CA    1 
ATOM   7212  C  C     . TYR B 1 405 ? -28.305 23.889  -26.123  1.00 43.03  ? 405 TYR B C     1 
ATOM   7213  O  O     . TYR B 1 405 ? -27.403 24.144  -25.317  1.00 37.83  ? 405 TYR B O     1 
ATOM   7214  C  CB    . TYR B 1 405 ? -28.634 25.074  -28.334  1.00 39.97  ? 405 TYR B CB    1 
ATOM   7215  C  CG    . TYR B 1 405 ? -28.463 26.383  -27.594  1.00 45.03  ? 405 TYR B CG    1 
ATOM   7216  C  CD1   . TYR B 1 405 ? -27.202 26.898  -27.356  1.00 45.39  ? 405 TYR B CD1   1 
ATOM   7217  C  CD2   . TYR B 1 405 ? -29.551 27.066  -27.071  1.00 42.53  ? 405 TYR B CD2   1 
ATOM   7218  C  CE1   . TYR B 1 405 ? -27.029 28.074  -26.639  1.00 49.51  ? 405 TYR B CE1   1 
ATOM   7219  C  CE2   . TYR B 1 405 ? -29.399 28.236  -26.349  1.00 46.40  ? 405 TYR B CE2   1 
ATOM   7220  C  CZ    . TYR B 1 405 ? -28.130 28.751  -26.142  1.00 52.94  ? 405 TYR B CZ    1 
ATOM   7221  O  OH    . TYR B 1 405 ? -27.953 29.928  -25.449  1.00 49.52  ? 405 TYR B OH    1 
ATOM   7222  N  N     . ASN B 1 406 ? -29.555 23.546  -25.759  1.00 41.72  ? 406 ASN B N     1 
ATOM   7223  C  CA    . ASN B 1 406 ? -29.990 23.645  -24.372  1.00 43.45  ? 406 ASN B CA    1 
ATOM   7224  C  C     . ASN B 1 406 ? -29.226 22.652  -23.528  1.00 40.98  ? 406 ASN B C     1 
ATOM   7225  O  O     . ASN B 1 406 ? -28.752 23.007  -22.452  1.00 43.69  ? 406 ASN B O     1 
ATOM   7226  C  CB    . ASN B 1 406 ? -31.486 23.401  -24.168  1.00 43.75  ? 406 ASN B CB    1 
ATOM   7227  C  CG    . ASN B 1 406 ? -32.314 24.525  -24.745  1.00 49.31  ? 406 ASN B CG    1 
ATOM   7228  O  OD1   . ASN B 1 406 ? -31.951 25.689  -24.630  1.00 56.11  ? 406 ASN B OD1   1 
ATOM   7229  N  ND2   . ASN B 1 406 ? -33.419 24.198  -25.383  1.00 49.22  ? 406 ASN B ND2   1 
ATOM   7230  N  N     . MET B 1 407 ? -29.138 21.422  -24.043  1.00 40.76  ? 407 MET B N     1 
ATOM   7231  C  CA    . MET B 1 407 ? -28.472 20.317  -23.372  1.00 43.70  ? 407 MET B CA    1 
ATOM   7232  C  C     . MET B 1 407 ? -27.021 20.672  -23.069  1.00 43.30  ? 407 MET B C     1 
ATOM   7233  O  O     . MET B 1 407 ? -26.526 20.392  -21.974  1.00 42.96  ? 407 MET B O     1 
ATOM   7234  C  CB    . MET B 1 407 ? -28.399 19.102  -24.301  1.00 48.95  ? 407 MET B CB    1 
ATOM   7235  C  CG    . MET B 1 407 ? -29.644 18.300  -24.392  1.00 53.99  ? 407 MET B CG    1 
ATOM   7236  S  SD    . MET B 1 407 ? -29.314 16.918  -25.499  1.00 49.19  ? 407 MET B SD    1 
ATOM   7237  C  CE    . MET B 1 407 ? -28.727 15.712  -24.311  1.00 48.03  ? 407 MET B CE    1 
ATOM   7238  N  N     . VAL B 1 408 ? -26.319 21.164  -24.104  1.00 35.77  ? 408 VAL B N     1 
ATOM   7239  C  CA    . VAL B 1 408 ? -24.882 21.375  -23.986  1.00 40.55  ? 408 VAL B CA    1 
ATOM   7240  C  C     . VAL B 1 408 ? -24.555 22.654  -23.202  1.00 39.65  ? 408 VAL B C     1 
ATOM   7241  O  O     . VAL B 1 408 ? -23.746 22.614  -22.275  1.00 43.27  ? 408 VAL B O     1 
ATOM   7242  C  CB    . VAL B 1 408 ? -24.193 21.379  -25.361  1.00 37.32  ? 408 VAL B CB    1 
ATOM   7243  C  CG1   . VAL B 1 408 ? -22.744 21.778  -25.225  1.00 36.79  ? 408 VAL B CG1   1 
ATOM   7244  C  CG2   . VAL B 1 408 ? -24.308 20.023  -26.052  1.00 38.00  ? 408 VAL B CG2   1 
ATOM   7245  N  N     . SER B 1 409 ? -25.144 23.787  -23.599  1.00 40.34  ? 409 SER B N     1 
ATOM   7246  C  CA    . SER B 1 409 ? -24.770 25.081  -23.031  1.00 43.35  ? 409 SER B CA    1 
ATOM   7247  C  C     . SER B 1 409 ? -25.031 25.102  -21.525  1.00 43.27  ? 409 SER B C     1 
ATOM   7248  O  O     . SER B 1 409 ? -24.218 25.638  -20.772  1.00 40.98  ? 409 SER B O     1 
ATOM   7249  C  CB    . SER B 1 409 ? -25.430 26.250  -23.751  1.00 45.12  ? 409 SER B CB    1 
ATOM   7250  O  OG    . SER B 1 409 ? -26.845 26.237  -23.599  1.00 49.66  ? 409 SER B OG    1 
ATOM   7251  N  N     . SER B 1 410 ? -26.105 24.426  -21.095  1.00 43.04  ? 410 SER B N     1 
ATOM   7252  C  CA    . SER B 1 410 ? -26.422 24.221  -19.686  1.00 46.22  ? 410 SER B CA    1 
ATOM   7253  C  C     . SER B 1 410 ? -25.288 23.537  -18.948  1.00 41.08  ? 410 SER B C     1 
ATOM   7254  O  O     . SER B 1 410 ? -24.855 23.992  -17.908  1.00 43.82  ? 410 SER B O     1 
ATOM   7255  C  CB    . SER B 1 410 ? -27.658 23.385  -19.517  1.00 50.60  ? 410 SER B CB    1 
ATOM   7256  O  OG    . SER B 1 410 ? -28.782 24.158  -19.866  1.00 62.92  ? 410 SER B OG    1 
ATOM   7257  N  N     . ARG B 1 411 ? -24.832 22.404  -19.458  1.00 40.24  ? 411 ARG B N     1 
ATOM   7258  C  CA    . ARG B 1 411 ? -23.858 21.671  -18.681  1.00 41.96  ? 411 ARG B CA    1 
ATOM   7259  C  C     . ARG B 1 411 ? -22.515 22.391  -18.736  1.00 38.30  ? 411 ARG B C     1 
ATOM   7260  O  O     . ARG B 1 411 ? -21.860 22.490  -17.725  1.00 37.92  ? 411 ARG B O     1 
ATOM   7261  C  CB    . ARG B 1 411 ? -23.785 20.210  -19.124  1.00 46.12  ? 411 ARG B CB    1 
ATOM   7262  C  CG    . ARG B 1 411 ? -24.974 19.385  -18.638  1.00 51.05  ? 411 ARG B CG    1 
ATOM   7263  C  CD    . ARG B 1 411 ? -24.555 17.936  -18.560  1.00 49.50  ? 411 ARG B CD    1 
ATOM   7264  N  NE    . ARG B 1 411 ? -25.570 17.119  -17.954  1.00 51.13  ? 411 ARG B NE    1 
ATOM   7265  C  CZ    . ARG B 1 411 ? -25.588 16.783  -16.675  1.00 52.19  ? 411 ARG B CZ    1 
ATOM   7266  N  NH1   . ARG B 1 411 ? -24.821 17.412  -15.809  1.00 51.66  ? 411 ARG B NH1   1 
ATOM   7267  N  NH2   . ARG B 1 411 ? -26.427 15.863  -16.255  1.00 52.55  ? 411 ARG B NH2   1 
ATOM   7268  N  N     . VAL B 1 412 ? -22.115 22.893  -19.902  1.00 37.16  ? 412 VAL B N     1 
ATOM   7269  C  CA    . VAL B 1 412 ? -20.828 23.565  -20.034  1.00 39.46  ? 412 VAL B CA    1 
ATOM   7270  C  C     . VAL B 1 412 ? -20.744 24.782  -19.100  1.00 37.94  ? 412 VAL B C     1 
ATOM   7271  O  O     . VAL B 1 412 ? -19.708 25.026  -18.474  1.00 35.13  ? 412 VAL B O     1 
ATOM   7272  C  CB    . VAL B 1 412 ? -20.599 23.969  -21.501  1.00 43.41  ? 412 VAL B CB    1 
ATOM   7273  C  CG1   . VAL B 1 412 ? -19.490 24.985  -21.664  1.00 46.74  ? 412 VAL B CG1   1 
ATOM   7274  C  CG2   . VAL B 1 412 ? -20.344 22.748  -22.366  1.00 44.29  ? 412 VAL B CG2   1 
ATOM   7275  N  N     . ARG B 1 413 ? -21.844 25.527  -18.995  1.00 38.95  ? 413 ARG B N     1 
ATOM   7276  C  CA    . ARG B 1 413 ? -21.876 26.739  -18.202  1.00 42.60  ? 413 ARG B CA    1 
ATOM   7277  C  C     . ARG B 1 413 ? -21.932 26.406  -16.717  1.00 48.11  ? 413 ARG B C     1 
ATOM   7278  O  O     . ARG B 1 413 ? -21.314 27.111  -15.925  1.00 44.26  ? 413 ARG B O     1 
ATOM   7279  C  CB    . ARG B 1 413 ? -23.015 27.646  -18.658  1.00 39.55  ? 413 ARG B CB    1 
ATOM   7280  C  CG    . ARG B 1 413 ? -22.661 28.460  -19.886  1.00 39.64  ? 413 ARG B CG    1 
ATOM   7281  C  CD    . ARG B 1 413 ? -23.897 29.168  -20.377  1.00 41.54  ? 413 ARG B CD    1 
ATOM   7282  N  NE    . ARG B 1 413 ? -24.358 30.075  -19.343  1.00 44.56  ? 413 ARG B NE    1 
ATOM   7283  C  CZ    . ARG B 1 413 ? -23.915 31.315  -19.163  1.00 45.82  ? 413 ARG B CZ    1 
ATOM   7284  N  NH1   . ARG B 1 413 ? -23.022 31.848  -19.982  1.00 44.96  ? 413 ARG B NH1   1 
ATOM   7285  N  NH2   . ARG B 1 413 ? -24.401 32.038  -18.175  1.00 45.29  ? 413 ARG B NH2   1 
ATOM   7286  N  N     . GLU B 1 414 ? -22.592 25.299  -16.355  1.00 49.42  ? 414 GLU B N     1 
ATOM   7287  C  CA    . GLU B 1 414 ? -22.611 24.865  -14.967  1.00 46.77  ? 414 GLU B CA    1 
ATOM   7288  C  C     . GLU B 1 414 ? -21.191 24.522  -14.526  1.00 42.58  ? 414 GLU B C     1 
ATOM   7289  O  O     . GLU B 1 414 ? -20.852 24.705  -13.365  1.00 48.26  ? 414 GLU B O     1 
ATOM   7290  C  CB    . GLU B 1 414 ? -23.536 23.661  -14.735  1.00 47.58  ? 414 GLU B CB    1 
ATOM   7291  C  CG    . GLU B 1 414 ? -23.283 22.999  -13.366  1.00 60.04  ? 414 GLU B CG    1 
ATOM   7292  C  CD    . GLU B 1 414 ? -24.250 21.941  -12.832  1.00 62.64  ? 414 GLU B CD    1 
ATOM   7293  O  OE1   . GLU B 1 414 ? -25.367 21.799  -13.371  1.00 64.05  ? 414 GLU B OE1   1 
ATOM   7294  O  OE2   . GLU B 1 414 ? -23.878 21.253  -11.875  1.00 54.75  ? 414 GLU B OE2   1 
ATOM   7295  N  N     . TYR B 1 415 ? -20.378 23.984  -15.436  1.00 41.19  ? 415 TYR B N     1 
ATOM   7296  C  CA    . TYR B 1 415 ? -19.008 23.604  -15.115  1.00 45.18  ? 415 TYR B CA    1 
ATOM   7297  C  C     . TYR B 1 415 ? -18.044 24.798  -15.141  1.00 40.80  ? 415 TYR B C     1 
ATOM   7298  O  O     . TYR B 1 415 ? -16.864 24.622  -14.844  1.00 47.30  ? 415 TYR B O     1 
ATOM   7299  C  CB    . TYR B 1 415 ? -18.489 22.529  -16.078  1.00 42.56  ? 415 TYR B CB    1 
ATOM   7300  C  CG    . TYR B 1 415 ? -18.907 21.123  -15.724  1.00 41.44  ? 415 TYR B CG    1 
ATOM   7301  C  CD1   . TYR B 1 415 ? -20.235 20.737  -15.755  1.00 43.45  ? 415 TYR B CD1   1 
ATOM   7302  C  CD2   . TYR B 1 415 ? -17.969 20.195  -15.292  1.00 41.65  ? 415 TYR B CD2   1 
ATOM   7303  C  CE1   . TYR B 1 415 ? -20.622 19.457  -15.381  1.00 39.92  ? 415 TYR B CE1   1 
ATOM   7304  C  CE2   . TYR B 1 415 ? -18.331 18.909  -14.943  1.00 44.35  ? 415 TYR B CE2   1 
ATOM   7305  C  CZ    . TYR B 1 415 ? -19.663 18.544  -14.993  1.00 41.17  ? 415 TYR B CZ    1 
ATOM   7306  O  OH    . TYR B 1 415 ? -19.999 17.265  -14.679  1.00 46.78  ? 415 TYR B OH    1 
ATOM   7307  N  N     . GLY B 1 416 ? -18.536 25.992  -15.488  1.00 41.60  ? 416 GLY B N     1 
ATOM   7308  C  CA    . GLY B 1 416 ? -17.765 27.228  -15.384  1.00 46.18  ? 416 GLY B CA    1 
ATOM   7309  C  C     . GLY B 1 416 ? -17.250 27.771  -16.724  1.00 48.70  ? 416 GLY B C     1 
ATOM   7310  O  O     . GLY B 1 416 ? -16.771 28.902  -16.783  1.00 44.66  ? 416 GLY B O     1 
ATOM   7311  N  N     . PHE B 1 417 ? -17.337 26.957  -17.786  1.00 46.02  ? 417 PHE B N     1 
ATOM   7312  C  CA    . PHE B 1 417 ? -16.864 27.310  -19.116  1.00 43.81  ? 417 PHE B CA    1 
ATOM   7313  C  C     . PHE B 1 417 ? -17.933 28.127  -19.819  1.00 42.90  ? 417 PHE B C     1 
ATOM   7314  O  O     . PHE B 1 417 ? -19.126 27.909  -19.589  1.00 41.30  ? 417 PHE B O     1 
ATOM   7315  C  CB    . PHE B 1 417 ? -16.590 26.041  -19.926  1.00 44.38  ? 417 PHE B CB    1 
ATOM   7316  C  CG    . PHE B 1 417 ? -15.580 25.110  -19.308  1.00 43.75  ? 417 PHE B CG    1 
ATOM   7317  C  CD1   . PHE B 1 417 ? -14.229 25.412  -19.340  1.00 46.82  ? 417 PHE B CD1   1 
ATOM   7318  C  CD2   . PHE B 1 417 ? -15.979 23.948  -18.671  1.00 42.94  ? 417 PHE B CD2   1 
ATOM   7319  C  CE1   . PHE B 1 417 ? -13.300 24.574  -18.739  1.00 47.34  ? 417 PHE B CE1   1 
ATOM   7320  C  CE2   . PHE B 1 417 ? -15.050 23.091  -18.102  1.00 41.78  ? 417 PHE B CE2   1 
ATOM   7321  C  CZ    . PHE B 1 417 ? -13.715 23.410  -18.128  1.00 48.66  ? 417 PHE B CZ    1 
ATOM   7322  N  N     . ASP B 1 418 ? -17.511 29.036  -20.703  1.00 41.75  ? 418 ASP B N     1 
ATOM   7323  C  CA    . ASP B 1 418 ? -18.455 29.643  -21.623  1.00 42.83  ? 418 ASP B CA    1 
ATOM   7324  C  C     . ASP B 1 418 ? -18.832 28.621  -22.689  1.00 43.14  ? 418 ASP B C     1 
ATOM   7325  O  O     . ASP B 1 418 ? -18.009 27.819  -23.128  1.00 39.86  ? 418 ASP B O     1 
ATOM   7326  C  CB    . ASP B 1 418 ? -17.933 30.909  -22.293  1.00 40.57  ? 418 ASP B CB    1 
ATOM   7327  C  CG    . ASP B 1 418 ? -18.013 32.127  -21.392  1.00 41.89  ? 418 ASP B CG    1 
ATOM   7328  O  OD1   . ASP B 1 418 ? -19.150 32.569  -21.108  1.00 39.04  ? 418 ASP B OD1   1 
ATOM   7329  O  OD2   . ASP B 1 418 ? -16.934 32.620  -20.991  1.00 42.06  ? 418 ASP B OD2   1 
ATOM   7330  N  N     . TYR B 1 419 ? -20.103 28.681  -23.082  1.00 38.53  ? 419 TYR B N     1 
ATOM   7331  C  CA    . TYR B 1 419 ? -20.597 27.930  -24.219  1.00 43.68  ? 419 TYR B CA    1 
ATOM   7332  C  C     . TYR B 1 419 ? -20.040 28.509  -25.520  1.00 39.40  ? 419 TYR B C     1 
ATOM   7333  O  O     . TYR B 1 419 ? -20.218 29.681  -25.838  1.00 39.66  ? 419 TYR B O     1 
ATOM   7334  C  CB    . TYR B 1 419 ? -22.126 27.959  -24.256  1.00 42.55  ? 419 TYR B CB    1 
ATOM   7335  C  CG    . TYR B 1 419 ? -22.714 27.399  -25.519  1.00 40.79  ? 419 TYR B CG    1 
ATOM   7336  C  CD1   . TYR B 1 419 ? -22.645 26.037  -25.784  1.00 43.36  ? 419 TYR B CD1   1 
ATOM   7337  C  CD2   . TYR B 1 419 ? -23.350 28.217  -26.443  1.00 42.55  ? 419 TYR B CD2   1 
ATOM   7338  C  CE1   . TYR B 1 419 ? -23.216 25.503  -26.930  1.00 40.12  ? 419 TYR B CE1   1 
ATOM   7339  C  CE2   . TYR B 1 419 ? -23.901 27.702  -27.612  1.00 43.68  ? 419 TYR B CE2   1 
ATOM   7340  C  CZ    . TYR B 1 419 ? -23.842 26.334  -27.846  1.00 42.70  ? 419 TYR B CZ    1 
ATOM   7341  O  OH    . TYR B 1 419 ? -24.397 25.772  -28.966  1.00 42.75  ? 419 TYR B OH    1 
ATOM   7342  N  N     . MET B 1 420 ? -19.355 27.650  -26.255  1.00 40.55  ? 420 MET B N     1 
ATOM   7343  C  CA    . MET B 1 420 ? -18.920 27.925  -27.611  1.00 43.12  ? 420 MET B CA    1 
ATOM   7344  C  C     . MET B 1 420 ? -19.413 26.768  -28.477  1.00 41.01  ? 420 MET B C     1 
ATOM   7345  O  O     . MET B 1 420 ? -19.010 25.629  -28.309  1.00 45.68  ? 420 MET B O     1 
ATOM   7346  C  CB    . MET B 1 420 ? -17.394 28.014  -27.685  1.00 41.50  ? 420 MET B CB    1 
ATOM   7347  C  CG    . MET B 1 420 ? -16.815 29.199  -26.954  1.00 43.18  ? 420 MET B CG    1 
ATOM   7348  S  SD    . MET B 1 420 ? -15.025 29.050  -26.989  1.00 50.86  ? 420 MET B SD    1 
ATOM   7349  C  CE    . MET B 1 420 ? -14.580 30.571  -26.162  1.00 52.90  ? 420 MET B CE    1 
ATOM   7350  N  N     . GLY B 1 421 ? -20.432 27.049  -29.263  1.00 47.64  ? 421 GLY B N     1 
ATOM   7351  C  CA    . GLY B 1 421 ? -21.008 26.052  -30.131  1.00 48.89  ? 421 GLY B CA    1 
ATOM   7352  C  C     . GLY B 1 421 ? -21.307 26.674  -31.487  1.00 50.67  ? 421 GLY B C     1 
ATOM   7353  O  O     . GLY B 1 421 ? -21.316 27.903  -31.629  1.00 45.03  ? 421 GLY B O     1 
ATOM   7354  N  N     . LEU B 1 422 ? -21.494 25.788  -32.469  1.00 43.55  ? 422 LEU B N     1 
ATOM   7355  C  CA    . LEU B 1 422 ? -22.000 26.156  -33.775  1.00 45.47  ? 422 LEU B CA    1 
ATOM   7356  C  C     . LEU B 1 422 ? -22.921 25.040  -34.258  1.00 46.11  ? 422 LEU B C     1 
ATOM   7357  O  O     . LEU B 1 422 ? -22.806 23.899  -33.811  1.00 44.42  ? 422 LEU B O     1 
ATOM   7358  C  CB    . LEU B 1 422 ? -20.816 26.383  -34.719  1.00 50.26  ? 422 LEU B CB    1 
ATOM   7359  C  CG    . LEU B 1 422 ? -19.922 25.174  -34.968  1.00 53.93  ? 422 LEU B CG    1 
ATOM   7360  C  CD1   . LEU B 1 422 ? -20.382 24.421  -36.196  1.00 57.09  ? 422 LEU B CD1   1 
ATOM   7361  C  CD2   . LEU B 1 422 ? -18.465 25.581  -35.125  1.00 56.54  ? 422 LEU B CD2   1 
ATOM   7362  N  N     . LEU B 1 423 ? -23.866 25.399  -35.125  1.00 42.42  ? 423 LEU B N     1 
ATOM   7363  C  CA    . LEU B 1 423 ? -24.600 24.407  -35.883  1.00 42.65  ? 423 LEU B CA    1 
ATOM   7364  C  C     . LEU B 1 423 ? -24.021 24.448  -37.284  1.00 41.97  ? 423 LEU B C     1 
ATOM   7365  O  O     . LEU B 1 423 ? -24.050 25.498  -37.908  1.00 43.44  ? 423 LEU B O     1 
ATOM   7366  C  CB    . LEU B 1 423 ? -26.098 24.726  -35.884  1.00 44.26  ? 423 LEU B CB    1 
ATOM   7367  C  CG    . LEU B 1 423 ? -26.853 24.447  -34.584  1.00 47.18  ? 423 LEU B CG    1 
ATOM   7368  C  CD1   . LEU B 1 423 ? -28.277 24.892  -34.729  1.00 60.99  ? 423 LEU B CD1   1 
ATOM   7369  C  CD2   . LEU B 1 423 ? -26.867 22.971  -34.205  1.00 43.18  ? 423 LEU B CD2   1 
ATOM   7370  N  N     . ALA B 1 424 ? -23.446 23.308  -37.704  1.00 42.26  ? 424 ALA B N     1 
ATOM   7371  C  CA    . ALA B 1 424 ? -22.821 23.137  -39.002  1.00 43.87  ? 424 ALA B CA    1 
ATOM   7372  C  C     . ALA B 1 424 ? -23.683 22.192  -39.822  1.00 42.85  ? 424 ALA B C     1 
ATOM   7373  O  O     . ALA B 1 424 ? -24.059 21.133  -39.320  1.00 42.35  ? 424 ALA B O     1 
ATOM   7374  C  CB    . ALA B 1 424 ? -21.418 22.580  -38.838  1.00 41.45  ? 424 ALA B CB    1 
ATOM   7375  N  N     . ILE B 1 425 ? -23.974 22.563  -41.075  1.00 38.23  ? 425 ILE B N     1 
ATOM   7376  C  CA    . ILE B 1 425 ? -24.604 21.619  -41.976  1.00 38.68  ? 425 ILE B CA    1 
ATOM   7377  C  C     . ILE B 1 425 ? -23.678 21.321  -43.146  1.00 36.01  ? 425 ILE B C     1 
ATOM   7378  O  O     . ILE B 1 425 ? -23.269 22.237  -43.840  1.00 36.94  ? 425 ILE B O     1 
ATOM   7379  C  CB    . ILE B 1 425 ? -25.962 22.128  -42.482  1.00 41.02  ? 425 ILE B CB    1 
ATOM   7380  C  CG1   . ILE B 1 425 ? -26.901 22.458  -41.329  1.00 42.65  ? 425 ILE B CG1   1 
ATOM   7381  C  CG2   . ILE B 1 425 ? -26.567 21.104  -43.438  1.00 40.83  ? 425 ILE B CG2   1 
ATOM   7382  C  CD1   . ILE B 1 425 ? -28.074 23.294  -41.741  1.00 44.54  ? 425 ILE B CD1   1 
ATOM   7383  N  N     . GLY B 1 426 ? -23.441 20.031  -43.410  1.00 38.12  ? 426 GLY B N     1 
ATOM   7384  C  CA    . GLY B 1 426 ? -22.667 19.601  -44.566  1.00 38.11  ? 426 GLY B CA    1 
ATOM   7385  C  C     . GLY B 1 426 ? -23.504 19.653  -45.835  1.00 41.67  ? 426 GLY B C     1 
ATOM   7386  O  O     . GLY B 1 426 ? -23.322 20.549  -46.664  1.00 48.78  ? 426 GLY B O     1 
ATOM   7387  N  N     . TRP B 1 427 ? -24.413 18.674  -45.963  1.00 41.08  ? 427 TRP B N     1 
ATOM   7388  C  CA    . TRP B 1 427 ? -25.410 18.635  -47.022  1.00 40.49  ? 427 TRP B CA    1 
ATOM   7389  C  C     . TRP B 1 427 ? -26.772 18.266  -46.432  1.00 42.21  ? 427 TRP B C     1 
ATOM   7390  O  O     . TRP B 1 427 ? -27.719 19.045  -46.525  1.00 41.15  ? 427 TRP B O     1 
ATOM   7391  C  CB    . TRP B 1 427 ? -24.981 17.653  -48.130  1.00 40.67  ? 427 TRP B CB    1 
ATOM   7392  C  CG    . TRP B 1 427 ? -25.788 17.720  -49.394  1.00 42.12  ? 427 TRP B CG    1 
ATOM   7393  C  CD1   . TRP B 1 427 ? -26.886 18.501  -49.638  1.00 45.69  ? 427 TRP B CD1   1 
ATOM   7394  C  CD2   . TRP B 1 427 ? -25.578 16.945  -50.593  1.00 44.81  ? 427 TRP B CD2   1 
ATOM   7395  N  NE1   . TRP B 1 427 ? -27.368 18.279  -50.905  1.00 44.84  ? 427 TRP B NE1   1 
ATOM   7396  C  CE2   . TRP B 1 427 ? -26.585 17.323  -51.514  1.00 47.11  ? 427 TRP B CE2   1 
ATOM   7397  C  CE3   . TRP B 1 427 ? -24.648 15.970  -50.985  1.00 44.33  ? 427 TRP B CE3   1 
ATOM   7398  C  CZ2   . TRP B 1 427 ? -26.665 16.765  -52.797  1.00 46.83  ? 427 TRP B CZ2   1 
ATOM   7399  C  CZ3   . TRP B 1 427 ? -24.755 15.402  -52.235  1.00 44.53  ? 427 TRP B CZ3   1 
ATOM   7400  C  CH2   . TRP B 1 427 ? -25.741 15.802  -53.135  1.00 44.58  ? 427 TRP B CH2   1 
ATOM   7401  N  N     . ARG B 1 428 ? -26.865 17.054  -45.858  1.00 38.41  ? 428 ARG B N     1 
ATOM   7402  C  CA    . ARG B 1 428 ? -28.084 16.579  -45.217  1.00 40.25  ? 428 ARG B CA    1 
ATOM   7403  C  C     . ARG B 1 428 ? -27.889 16.383  -43.712  1.00 39.71  ? 428 ARG B C     1 
ATOM   7404  O  O     . ARG B 1 428 ? -28.830 15.990  -43.021  1.00 37.20  ? 428 ARG B O     1 
ATOM   7405  C  CB    . ARG B 1 428 ? -28.494 15.263  -45.884  1.00 38.07  ? 428 ARG B CB    1 
ATOM   7406  C  CG    . ARG B 1 428 ? -29.150 15.432  -47.246  1.00 34.53  ? 428 ARG B CG    1 
ATOM   7407  C  CD    . ARG B 1 428 ? -29.359 14.064  -47.808  1.00 33.20  ? 428 ARG B CD    1 
ATOM   7408  N  NE    . ARG B 1 428 ? -30.140 14.063  -49.028  1.00 33.64  ? 428 ARG B NE    1 
ATOM   7409  C  CZ    . ARG B 1 428 ? -29.761 14.511  -50.206  1.00 37.57  ? 428 ARG B CZ    1 
ATOM   7410  N  NH1   . ARG B 1 428 ? -28.521 14.937  -50.429  1.00 36.56  ? 428 ARG B NH1   1 
ATOM   7411  N  NH2   . ARG B 1 428 ? -30.662 14.515  -51.173  1.00 36.47  ? 428 ARG B NH2   1 
ATOM   7412  N  N     . ASP B 1 429 ? -26.667 16.663  -43.231  1.00 36.80  ? 429 ASP B N     1 
ATOM   7413  C  CA    . ASP B 1 429 ? -26.226 16.342  -41.881  1.00 37.79  ? 429 ASP B CA    1 
ATOM   7414  C  C     . ASP B 1 429 ? -26.044 17.622  -41.052  1.00 44.45  ? 429 ASP B C     1 
ATOM   7415  O  O     . ASP B 1 429 ? -25.325 18.526  -41.471  1.00 42.89  ? 429 ASP B O     1 
ATOM   7416  C  CB    . ASP B 1 429 ? -24.919 15.550  -41.940  1.00 38.63  ? 429 ASP B CB    1 
ATOM   7417  C  CG    . ASP B 1 429 ? -23.801 16.228  -42.718  1.00 36.91  ? 429 ASP B CG    1 
ATOM   7418  O  OD1   . ASP B 1 429 ? -24.076 16.712  -43.831  1.00 36.28  ? 429 ASP B OD1   1 
ATOM   7419  O  OD2   . ASP B 1 429 ? -22.650 16.256  -42.211  1.00 40.94  ? 429 ASP B OD2   1 
ATOM   7420  N  N     . LEU B 1 430 ? -26.721 17.696  -39.891  1.00 41.82  ? 430 LEU B N     1 
ATOM   7421  C  CA    . LEU B 1 430 ? -26.518 18.748  -38.900  1.00 40.61  ? 430 LEU B CA    1 
ATOM   7422  C  C     . LEU B 1 430 ? -25.509 18.247  -37.879  1.00 33.63  ? 430 LEU B C     1 
ATOM   7423  O  O     . LEU B 1 430 ? -25.501 17.085  -37.502  1.00 35.49  ? 430 LEU B O     1 
ATOM   7424  C  CB    . LEU B 1 430 ? -27.838 19.102  -38.208  1.00 41.48  ? 430 LEU B CB    1 
ATOM   7425  C  CG    . LEU B 1 430 ? -27.784 20.214  -37.148  1.00 39.75  ? 430 LEU B CG    1 
ATOM   7426  C  CD1   . LEU B 1 430 ? -27.660 21.569  -37.794  1.00 39.40  ? 430 LEU B CD1   1 
ATOM   7427  C  CD2   . LEU B 1 430 ? -29.030 20.210  -36.248  1.00 41.90  ? 430 LEU B CD2   1 
ATOM   7428  N  N     . HIS B 1 431 ? -24.618 19.132  -37.464  1.00 36.21  ? 431 HIS B N     1 
ATOM   7429  C  CA    . HIS B 1 431 ? -23.743 18.841  -36.351  1.00 36.10  ? 431 HIS B CA    1 
ATOM   7430  C  C     . HIS B 1 431 ? -23.839 20.002  -35.390  1.00 39.80  ? 431 HIS B C     1 
ATOM   7431  O  O     . HIS B 1 431 ? -23.468 21.111  -35.791  1.00 36.13  ? 431 HIS B O     1 
ATOM   7432  C  CB    . HIS B 1 431 ? -22.287 18.757  -36.807  1.00 37.90  ? 431 HIS B CB    1 
ATOM   7433  C  CG    . HIS B 1 431 ? -22.016 17.660  -37.757  1.00 40.18  ? 431 HIS B CG    1 
ATOM   7434  N  ND1   . HIS B 1 431 ? -22.501 17.647  -39.043  1.00 42.84  ? 431 HIS B ND1   1 
ATOM   7435  C  CD2   . HIS B 1 431 ? -21.297 16.537  -37.611  1.00 39.08  ? 431 HIS B CD2   1 
ATOM   7436  C  CE1   . HIS B 1 431 ? -22.055 16.564  -39.660  1.00 39.39  ? 431 HIS B CE1   1 
ATOM   7437  N  NE2   . HIS B 1 431 ? -21.345 15.865  -38.796  1.00 43.87  ? 431 HIS B NE2   1 
ATOM   7438  N  N     . HIS B 1 432 ? -24.347 19.747  -34.168  1.00 40.94  ? 432 HIS B N     1 
ATOM   7439  C  CA    . HIS B 1 432 ? -24.098 20.652  -33.051  1.00 40.92  ? 432 HIS B CA    1 
ATOM   7440  C  C     . HIS B 1 432 ? -22.662 20.407  -32.578  1.00 36.57  ? 432 HIS B C     1 
ATOM   7441  O  O     . HIS B 1 432 ? -22.353 19.323  -32.090  1.00 37.92  ? 432 HIS B O     1 
ATOM   7442  C  CB    . HIS B 1 432 ? -25.099 20.447  -31.907  1.00 38.31  ? 432 HIS B CB    1 
ATOM   7443  C  CG    . HIS B 1 432 ? -24.834 21.416  -30.813  1.00 39.85  ? 432 HIS B CG    1 
ATOM   7444  N  ND1   . HIS B 1 432 ? -23.987 21.102  -29.777  1.00 42.77  ? 432 HIS B ND1   1 
ATOM   7445  C  CD2   . HIS B 1 432 ? -25.153 22.721  -30.661  1.00 40.52  ? 432 HIS B CD2   1 
ATOM   7446  C  CE1   . HIS B 1 432 ? -23.852 22.175  -28.996  1.00 46.13  ? 432 HIS B CE1   1 
ATOM   7447  N  NE2   . HIS B 1 432 ? -24.551 23.157  -29.502  1.00 40.00  ? 432 HIS B NE2   1 
ATOM   7448  N  N     . VAL B 1 433 ? -21.770 21.365  -32.832  1.00 37.32  ? 433 VAL B N     1 
ATOM   7449  C  CA    . VAL B 1 433 ? -20.356 21.250  -32.462  1.00 34.83  ? 433 VAL B CA    1 
ATOM   7450  C  C     . VAL B 1 433 ? -20.142 22.069  -31.194  1.00 36.64  ? 433 VAL B C     1 
ATOM   7451  O  O     . VAL B 1 433 ? -20.480 23.246  -31.172  1.00 39.22  ? 433 VAL B O     1 
ATOM   7452  C  CB    . VAL B 1 433 ? -19.385 21.777  -33.527  1.00 33.56  ? 433 VAL B CB    1 
ATOM   7453  C  CG1   . VAL B 1 433 ? -17.934 21.601  -33.076  1.00 32.82  ? 433 VAL B CG1   1 
ATOM   7454  C  CG2   . VAL B 1 433 ? -19.607 21.160  -34.895  1.00 33.67  ? 433 VAL B CG2   1 
ATOM   7455  N  N     . THR B 1 434 ? -19.635 21.415  -30.145  1.00 44.97  ? 434 THR B N     1 
ATOM   7456  C  CA    . THR B 1 434 ? -19.293 22.048  -28.881  1.00 47.35  ? 434 THR B CA    1 
ATOM   7457  C  C     . THR B 1 434 ? -17.782 22.183  -28.861  1.00 44.98  ? 434 THR B C     1 
ATOM   7458  O  O     . THR B 1 434 ? -17.103 21.179  -29.069  1.00 38.92  ? 434 THR B O     1 
ATOM   7459  C  CB    . THR B 1 434 ? -19.739 21.198  -27.682  1.00 45.41  ? 434 THR B CB    1 
ATOM   7460  O  OG1   . THR B 1 434 ? -21.141 20.911  -27.772  1.00 46.39  ? 434 THR B OG1   1 
ATOM   7461  C  CG2   . THR B 1 434 ? -19.461 21.868  -26.357  1.00 45.16  ? 434 THR B CG2   1 
ATOM   7462  N  N     . VAL B 1 435 ? -17.281 23.418  -28.685  1.00 43.02  ? 435 VAL B N     1 
ATOM   7463  C  CA    . VAL B 1 435 ? -15.869 23.577  -28.406  1.00 43.28  ? 435 VAL B CA    1 
ATOM   7464  C  C     . VAL B 1 435 ? -15.735 24.115  -26.982  1.00 41.46  ? 435 VAL B C     1 
ATOM   7465  O  O     . VAL B 1 435 ? -16.461 25.019  -26.571  1.00 42.05  ? 435 VAL B O     1 
ATOM   7466  C  CB    . VAL B 1 435 ? -15.086 24.388  -29.462  1.00 47.80  ? 435 VAL B CB    1 
ATOM   7467  C  CG1   . VAL B 1 435 ? -15.871 24.613  -30.745  1.00 46.54  ? 435 VAL B CG1   1 
ATOM   7468  C  CG2   . VAL B 1 435 ? -14.535 25.694  -28.934  1.00 51.12  ? 435 VAL B CG2   1 
ATOM   7469  N  N     . ILE B 1 436 ? -14.854 23.451  -26.232  1.00 44.07  ? 436 ILE B N     1 
ATOM   7470  C  CA    . ILE B 1 436 ? -14.577 23.776  -24.851  1.00 46.70  ? 436 ILE B CA    1 
ATOM   7471  C  C     . ILE B 1 436 ? -13.105 24.163  -24.773  1.00 44.49  ? 436 ILE B C     1 
ATOM   7472  O  O     . ILE B 1 436 ? -12.229 23.337  -25.023  1.00 44.52  ? 436 ILE B O     1 
ATOM   7473  C  CB    . ILE B 1 436 ? -14.882 22.590  -23.911  1.00 44.33  ? 436 ILE B CB    1 
ATOM   7474  C  CG1   . ILE B 1 436 ? -16.275 22.006  -24.135  1.00 44.82  ? 436 ILE B CG1   1 
ATOM   7475  C  CG2   . ILE B 1 436 ? -14.694 23.023  -22.466  1.00 43.93  ? 436 ILE B CG2   1 
ATOM   7476  C  CD1   . ILE B 1 436 ? -16.514 20.703  -23.401  1.00 44.20  ? 436 ILE B CD1   1 
ATOM   7477  N  N     . VAL B 1 437 ? -12.861 25.426  -24.409  1.00 41.96  ? 437 VAL B N     1 
ATOM   7478  C  CA    . VAL B 1 437 ? -11.511 25.909  -24.180  1.00 40.97  ? 437 VAL B CA    1 
ATOM   7479  C  C     . VAL B 1 437 ? -11.192 25.757  -22.698  1.00 41.65  ? 437 VAL B C     1 
ATOM   7480  O  O     . VAL B 1 437 ? -11.969 26.161  -21.849  1.00 42.72  ? 437 VAL B O     1 
ATOM   7481  C  CB    . VAL B 1 437 ? -11.373 27.370  -24.639  1.00 40.69  ? 437 VAL B CB    1 
ATOM   7482  C  CG1   . VAL B 1 437 ? -10.003 27.948  -24.294  1.00 46.65  ? 437 VAL B CG1   1 
ATOM   7483  C  CG2   . VAL B 1 437 ? -11.664 27.500  -26.129  1.00 39.14  ? 437 VAL B CG2   1 
ATOM   7484  N  N     . TYR B 1 438 ? -10.025 25.204  -22.387  1.00 39.09  ? 438 TYR B N     1 
ATOM   7485  C  CA    . TYR B 1 438 ? -9.715  24.888  -21.008  1.00 40.22  ? 438 TYR B CA    1 
ATOM   7486  C  C     . TYR B 1 438 ? -8.216  25.060  -20.791  1.00 39.54  ? 438 TYR B C     1 
ATOM   7487  O  O     . TYR B 1 438 ? -7.442  24.970  -21.741  1.00 40.00  ? 438 TYR B O     1 
ATOM   7488  C  CB    . TYR B 1 438 ? -10.155 23.451  -20.683  1.00 41.61  ? 438 TYR B CB    1 
ATOM   7489  C  CG    . TYR B 1 438 ? -9.468  22.394  -21.506  1.00 44.37  ? 438 TYR B CG    1 
ATOM   7490  C  CD1   . TYR B 1 438 ? -9.858  22.140  -22.807  1.00 46.47  ? 438 TYR B CD1   1 
ATOM   7491  C  CD2   . TYR B 1 438 ? -8.403  21.665  -21.002  1.00 51.57  ? 438 TYR B CD2   1 
ATOM   7492  C  CE1   . TYR B 1 438 ? -9.235  21.167  -23.573  1.00 55.31  ? 438 TYR B CE1   1 
ATOM   7493  C  CE2   . TYR B 1 438 ? -7.748  20.704  -21.764  1.00 53.44  ? 438 TYR B CE2   1 
ATOM   7494  C  CZ    . TYR B 1 438 ? -8.160  20.456  -23.062  1.00 56.64  ? 438 TYR B CZ    1 
ATOM   7495  O  OH    . TYR B 1 438 ? -7.543  19.499  -23.849  1.00 56.53  ? 438 TYR B OH    1 
ATOM   7496  N  N     . ASP B 1 439 ? -7.828  25.284  -19.537  1.00 43.92  ? 439 ASP B N     1 
ATOM   7497  C  CA    . ASP B 1 439 ? -6.429  25.382  -19.149  1.00 47.36  ? 439 ASP B CA    1 
ATOM   7498  C  C     . ASP B 1 439 ? -5.837  23.975  -18.987  1.00 47.70  ? 439 ASP B C     1 
ATOM   7499  O  O     . ASP B 1 439 ? -6.025  23.317  -17.964  1.00 46.33  ? 439 ASP B O     1 
ATOM   7500  C  CB    . ASP B 1 439 ? -6.317  26.253  -17.897  1.00 49.28  ? 439 ASP B CB    1 
ATOM   7501  C  CG    . ASP B 1 439 ? -4.899  26.426  -17.380  1.00 53.58  ? 439 ASP B CG    1 
ATOM   7502  O  OD1   . ASP B 1 439 ? -3.959  25.989  -18.078  1.00 46.28  ? 439 ASP B OD1   1 
ATOM   7503  O  OD2   . ASP B 1 439 ? -4.762  26.977  -16.269  1.00 57.16  ? 439 ASP B OD2   1 
ATOM   7504  N  N     . LYS B 1 440 ? -5.057  23.563  -19.990  1.00 50.90  ? 440 LYS B N     1 
ATOM   7505  C  CA    . LYS B 1 440 ? -4.519  22.220  -20.120  1.00 56.89  ? 440 LYS B CA    1 
ATOM   7506  C  C     . LYS B 1 440 ? -3.316  22.018  -19.204  1.00 58.01  ? 440 LYS B C     1 
ATOM   7507  O  O     . LYS B 1 440 ? -2.777  20.909  -19.159  1.00 53.03  ? 440 LYS B O     1 
ATOM   7508  C  CB    . LYS B 1 440 ? -4.070  21.978  -21.566  1.00 63.06  ? 440 LYS B CB    1 
ATOM   7509  C  CG    . LYS B 1 440 ? -2.895  22.850  -22.003  1.00 72.58  ? 440 LYS B CG    1 
ATOM   7510  C  CD    . LYS B 1 440 ? -3.010  23.412  -23.404  1.00 88.49  ? 440 LYS B CD    1 
ATOM   7511  C  CE    . LYS B 1 440 ? -2.101  24.601  -23.660  1.00 96.28  ? 440 LYS B CE    1 
ATOM   7512  N  NZ    . LYS B 1 440 ? -0.671  24.257  -23.477  1.00 96.31  ? 440 LYS B NZ    1 
ATOM   7513  N  N     . THR B 1 441 ? -2.879  23.085  -18.517  1.00 57.60  ? 441 THR B N     1 
ATOM   7514  C  CA    . THR B 1 441 ? -1.786  22.980  -17.557  1.00 57.35  ? 441 THR B CA    1 
ATOM   7515  C  C     . THR B 1 441 ? -2.328  22.771  -16.145  1.00 61.20  ? 441 THR B C     1 
ATOM   7516  O  O     . THR B 1 441 ? -1.558  22.484  -15.243  1.00 57.68  ? 441 THR B O     1 
ATOM   7517  C  CB    . THR B 1 441 ? -0.892  24.228  -17.529  1.00 57.18  ? 441 THR B CB    1 
ATOM   7518  O  OG1   . THR B 1 441 ? -1.663  25.288  -16.963  1.00 55.30  ? 441 THR B OG1   1 
ATOM   7519  C  CG2   . THR B 1 441 ? -0.348  24.620  -18.890  1.00 57.77  ? 441 THR B CG2   1 
ATOM   7520  N  N     . ASP B 1 442 ? -3.646  22.911  -15.960  1.00 56.08  ? 442 ASP B N     1 
ATOM   7521  C  CA    . ASP B 1 442 ? -4.256  22.811  -14.645  1.00 57.57  ? 442 ASP B CA    1 
ATOM   7522  C  C     . ASP B 1 442 ? -4.946  21.452  -14.474  1.00 61.22  ? 442 ASP B C     1 
ATOM   7523  O  O     . ASP B 1 442 ? -5.922  21.164  -15.163  1.00 61.26  ? 442 ASP B O     1 
ATOM   7524  C  CB    . ASP B 1 442 ? -5.232  23.967  -14.439  1.00 52.94  ? 442 ASP B CB    1 
ATOM   7525  C  CG    . ASP B 1 442 ? -5.894  23.954  -13.076  1.00 51.37  ? 442 ASP B CG    1 
ATOM   7526  O  OD1   . ASP B 1 442 ? -5.795  22.924  -12.407  1.00 57.02  ? 442 ASP B OD1   1 
ATOM   7527  O  OD2   . ASP B 1 442 ? -6.501  24.975  -12.704  1.00 59.60  ? 442 ASP B OD2   1 
ATOM   7528  N  N     . PRO B 1 443 ? -4.501  20.588  -13.524  1.00 63.03  ? 443 PRO B N     1 
ATOM   7529  C  CA    . PRO B 1 443 ? -5.115  19.265  -13.316  1.00 56.11  ? 443 PRO B CA    1 
ATOM   7530  C  C     . PRO B 1 443 ? -6.591  19.251  -12.927  1.00 49.77  ? 443 PRO B C     1 
ATOM   7531  O  O     . PRO B 1 443 ? -7.294  18.312  -13.288  1.00 48.04  ? 443 PRO B O     1 
ATOM   7532  C  CB    . PRO B 1 443 ? -4.314  18.637  -12.161  1.00 56.60  ? 443 PRO B CB    1 
ATOM   7533  C  CG    . PRO B 1 443 ? -3.001  19.410  -12.163  1.00 60.68  ? 443 PRO B CG    1 
ATOM   7534  C  CD    . PRO B 1 443 ? -3.350  20.808  -12.637  1.00 58.13  ? 443 PRO B CD    1 
ATOM   7535  N  N     . ASP B 1 444 ? -7.046  20.268  -12.180  1.00 46.24  ? 444 ASP B N     1 
ATOM   7536  C  CA    . ASP B 1 444 ? -8.434  20.329  -11.745  1.00 53.99  ? 444 ASP B CA    1 
ATOM   7537  C  C     . ASP B 1 444 ? -9.355  20.768  -12.882  1.00 56.87  ? 444 ASP B C     1 
ATOM   7538  O  O     . ASP B 1 444 ? -10.521 20.365  -12.901  1.00 55.97  ? 444 ASP B O     1 
ATOM   7539  C  CB    . ASP B 1 444 ? -8.679  21.282  -10.570  1.00 56.53  ? 444 ASP B CB    1 
ATOM   7540  C  CG    . ASP B 1 444 ? -7.810  21.044  -9.348   1.00 61.67  ? 444 ASP B CG    1 
ATOM   7541  O  OD1   . ASP B 1 444 ? -7.532  19.871  -9.014   1.00 61.25  ? 444 ASP B OD1   1 
ATOM   7542  O  OD2   . ASP B 1 444 ? -7.424  22.042  -8.741   1.00 65.29  ? 444 ASP B OD2   1 
ATOM   7543  N  N     . GLU B 1 445 ? -8.858  21.646  -13.767  1.00 53.15  ? 445 GLU B N     1 
ATOM   7544  C  CA    . GLU B 1 445 ? -9.573  22.011  -14.983  1.00 51.34  ? 445 GLU B CA    1 
ATOM   7545  C  C     . GLU B 1 445 ? -9.618  20.816  -15.926  1.00 47.48  ? 445 GLU B C     1 
ATOM   7546  O  O     . GLU B 1 445 ? -10.653 20.561  -16.528  1.00 54.03  ? 445 GLU B O     1 
ATOM   7547  C  CB    . GLU B 1 445 ? -8.931  23.210  -15.692  1.00 51.47  ? 445 GLU B CB    1 
ATOM   7548  C  CG    . GLU B 1 445 ? -9.344  24.562  -15.130  1.00 56.69  ? 445 GLU B CG    1 
ATOM   7549  C  CD    . GLU B 1 445 ? -10.376 25.287  -15.981  1.00 68.15  ? 445 GLU B CD    1 
ATOM   7550  O  OE1   . GLU B 1 445 ? -10.034 25.690  -17.153  1.00 57.58  ? 445 GLU B OE1   1 
ATOM   7551  O  OE2   . GLU B 1 445 ? -11.525 25.418  -15.497  1.00 71.87  ? 445 GLU B OE2   1 
ATOM   7552  N  N     . ARG B 1 446 ? -8.492  20.112  -16.073  1.00 46.29  ? 446 ARG B N     1 
ATOM   7553  C  CA    . ARG B 1 446 ? -8.422  18.950  -16.941  1.00 49.60  ? 446 ARG B CA    1 
ATOM   7554  C  C     . ARG B 1 446 ? -9.430  17.909  -16.474  1.00 53.56  ? 446 ARG B C     1 
ATOM   7555  O  O     . ARG B 1 446 ? -10.069 17.232  -17.282  1.00 50.38  ? 446 ARG B O     1 
ATOM   7556  C  CB    . ARG B 1 446 ? -7.029  18.321  -16.936  1.00 48.79  ? 446 ARG B CB    1 
ATOM   7557  C  CG    . ARG B 1 446 ? -5.986  19.154  -17.667  1.00 56.29  ? 446 ARG B CG    1 
ATOM   7558  C  CD    . ARG B 1 446 ? -4.858  18.307  -18.212  1.00 56.26  ? 446 ARG B CD    1 
ATOM   7559  N  NE    . ARG B 1 446 ? -4.057  17.710  -17.157  1.00 58.16  ? 446 ARG B NE    1 
ATOM   7560  C  CZ    . ARG B 1 446 ? -2.885  18.176  -16.745  1.00 60.06  ? 446 ARG B CZ    1 
ATOM   7561  N  NH1   . ARG B 1 446 ? -2.422  19.307  -17.241  1.00 68.24  ? 446 ARG B NH1   1 
ATOM   7562  N  NH2   . ARG B 1 446 ? -2.198  17.536  -15.818  1.00 58.78  ? 446 ARG B NH2   1 
ATOM   7563  N  N     . LYS B 1 447 ? -9.528  17.795  -15.151  1.00 49.38  ? 447 LYS B N     1 
ATOM   7564  C  CA    . LYS B 1 447 ? -10.449 16.883  -14.509  1.00 53.92  ? 447 LYS B CA    1 
ATOM   7565  C  C     . LYS B 1 447 ? -11.889 17.213  -14.897  1.00 49.34  ? 447 LYS B C     1 
ATOM   7566  O  O     . LYS B 1 447 ? -12.642 16.326  -15.292  1.00 47.78  ? 447 LYS B O     1 
ATOM   7567  C  CB    . LYS B 1 447 ? -10.259 16.955  -12.990  1.00 56.73  ? 447 LYS B CB    1 
ATOM   7568  C  CG    . LYS B 1 447 ? -11.248 16.136  -12.176  1.00 58.34  ? 447 LYS B CG    1 
ATOM   7569  C  CD    . LYS B 1 447 ? -11.196 14.666  -12.509  1.00 60.25  ? 447 LYS B CD    1 
ATOM   7570  C  CE    . LYS B 1 447 ? -12.417 13.922  -12.021  1.00 62.56  ? 447 LYS B CE    1 
ATOM   7571  N  NZ    . LYS B 1 447 ? -12.386 12.514  -12.470  1.00 62.82  ? 447 LYS B NZ    1 
ATOM   7572  N  N     . LYS B 1 448 ? -12.276 18.483  -14.766  1.00 47.94  ? 448 LYS B N     1 
ATOM   7573  C  CA    . LYS B 1 448 ? -13.656 18.872  -15.013  1.00 49.28  ? 448 LYS B CA    1 
ATOM   7574  C  C     . LYS B 1 448 ? -13.973 18.768  -16.497  1.00 47.98  ? 448 LYS B C     1 
ATOM   7575  O  O     . LYS B 1 448 ? -15.125 18.527  -16.847  1.00 46.47  ? 448 LYS B O     1 
ATOM   7576  C  CB    . LYS B 1 448 ? -13.925 20.327  -14.641  1.00 51.57  ? 448 LYS B CB    1 
ATOM   7577  C  CG    . LYS B 1 448 ? -13.760 20.664  -13.168  1.00 54.49  ? 448 LYS B CG    1 
ATOM   7578  C  CD    . LYS B 1 448 ? -13.525 22.141  -12.926  1.00 56.06  ? 448 LYS B CD    1 
ATOM   7579  C  CE    . LYS B 1 448 ? -14.427 23.052  -13.732  1.00 55.04  ? 448 LYS B CE    1 
ATOM   7580  N  NZ    . LYS B 1 448 ? -14.332 24.461  -13.279  1.00 60.17  ? 448 LYS B NZ    1 
ATOM   7581  N  N     . LEU B 1 449 ? -12.971 19.026  -17.353  1.00 42.79  ? 449 LEU B N     1 
ATOM   7582  C  CA    . LEU B 1 449 ? -13.205 18.974  -18.777  1.00 43.44  ? 449 LEU B CA    1 
ATOM   7583  C  C     . LEU B 1 449 ? -13.497 17.525  -19.158  1.00 46.50  ? 449 LEU B C     1 
ATOM   7584  O  O     . LEU B 1 449 ? -14.374 17.257  -19.968  1.00 45.01  ? 449 LEU B O     1 
ATOM   7585  C  CB    . LEU B 1 449 ? -11.984 19.449  -19.559  1.00 47.21  ? 449 LEU B CB    1 
ATOM   7586  C  CG    . LEU B 1 449 ? -12.116 19.237  -21.067  1.00 51.02  ? 449 LEU B CG    1 
ATOM   7587  C  CD1   . LEU B 1 449 ? -12.553 20.510  -21.756  1.00 51.24  ? 449 LEU B CD1   1 
ATOM   7588  C  CD2   . LEU B 1 449 ? -10.852 18.673  -21.661  1.00 58.78  ? 449 LEU B CD2   1 
ATOM   7589  N  N     . ASP B 1 450 ? -12.704 16.609  -18.601  1.00 43.58  ? 450 ASP B N     1 
ATOM   7590  C  CA    . ASP B 1 450 ? -12.777 15.205  -18.944  1.00 42.45  ? 450 ASP B CA    1 
ATOM   7591  C  C     . ASP B 1 450 ? -14.163 14.677  -18.603  1.00 42.96  ? 450 ASP B C     1 
ATOM   7592  O  O     . ASP B 1 450 ? -14.792 13.960  -19.375  1.00 43.85  ? 450 ASP B O     1 
ATOM   7593  C  CB    . ASP B 1 450 ? -11.700 14.425  -18.197  1.00 45.91  ? 450 ASP B CB    1 
ATOM   7594  C  CG    . ASP B 1 450 ? -11.609 12.982  -18.660  1.00 59.75  ? 450 ASP B CG    1 
ATOM   7595  O  OD1   . ASP B 1 450 ? -12.077 12.691  -19.784  1.00 62.52  ? 450 ASP B OD1   1 
ATOM   7596  O  OD2   . ASP B 1 450 ? -11.076 12.162  -17.898  1.00 59.09  ? 450 ASP B OD2   1 
ATOM   7597  N  N     . GLU B 1 451 ? -14.639 15.071  -17.426  1.00 47.50  ? 451 GLU B N     1 
ATOM   7598  C  CA    . GLU B 1 451 ? -15.917 14.625  -16.901  1.00 45.98  ? 451 GLU B CA    1 
ATOM   7599  C  C     . GLU B 1 451 ? -17.067 15.206  -17.718  1.00 45.39  ? 451 GLU B C     1 
ATOM   7600  O  O     . GLU B 1 451 ? -17.971 14.486  -18.137  1.00 41.23  ? 451 GLU B O     1 
ATOM   7601  C  CB    . GLU B 1 451 ? -16.017 15.076  -15.445  1.00 45.21  ? 451 GLU B CB    1 
ATOM   7602  C  CG    . GLU B 1 451 ? -17.319 14.718  -14.779  1.00 41.45  ? 451 GLU B CG    1 
ATOM   7603  C  CD    . GLU B 1 451 ? -17.463 15.320  -13.394  1.00 45.53  ? 451 GLU B CD    1 
ATOM   7604  O  OE1   . GLU B 1 451 ? -16.783 14.818  -12.484  1.00 44.90  ? 451 GLU B OE1   1 
ATOM   7605  O  OE2   . GLU B 1 451 ? -18.306 16.248  -13.218  1.00 46.22  ? 451 GLU B OE2   1 
ATOM   7606  N  N     . LEU B 1 452 ? -17.044 16.534  -17.880  1.00 44.06  ? 452 LEU B N     1 
ATOM   7607  C  CA    . LEU B 1 452 ? -18.010 17.231  -18.704  1.00 40.46  ? 452 LEU B CA    1 
ATOM   7608  C  C     . LEU B 1 452 ? -18.063 16.569  -20.076  1.00 39.27  ? 452 LEU B C     1 
ATOM   7609  O  O     . LEU B 1 452 ? -19.143 16.386  -20.612  1.00 38.14  ? 452 LEU B O     1 
ATOM   7610  C  CB    . LEU B 1 452 ? -17.610 18.707  -18.802  1.00 38.56  ? 452 LEU B CB    1 
ATOM   7611  C  CG    . LEU B 1 452 ? -18.361 19.556  -19.827  1.00 39.48  ? 452 LEU B CG    1 
ATOM   7612  C  CD1   . LEU B 1 452 ? -19.858 19.546  -19.562  1.00 39.63  ? 452 LEU B CD1   1 
ATOM   7613  C  CD2   . LEU B 1 452 ? -17.842 20.997  -19.826  1.00 38.97  ? 452 LEU B CD2   1 
ATOM   7614  N  N     . PHE B 1 453 ? -16.904 16.210  -20.645  1.00 34.14  ? 453 PHE B N     1 
ATOM   7615  C  CA    . PHE B 1 453 ? -16.891 15.662  -21.988  1.00 37.95  ? 453 PHE B CA    1 
ATOM   7616  C  C     . PHE B 1 453 ? -17.563 14.296  -22.007  1.00 41.93  ? 453 PHE B C     1 
ATOM   7617  O  O     . PHE B 1 453 ? -18.274 13.986  -22.956  1.00 41.31  ? 453 PHE B O     1 
ATOM   7618  C  CB    . PHE B 1 453 ? -15.475 15.575  -22.557  1.00 37.37  ? 453 PHE B CB    1 
ATOM   7619  C  CG    . PHE B 1 453 ? -15.381 15.078  -23.973  1.00 38.54  ? 453 PHE B CG    1 
ATOM   7620  C  CD1   . PHE B 1 453 ? -15.316 13.716  -24.244  1.00 46.21  ? 453 PHE B CD1   1 
ATOM   7621  C  CD2   . PHE B 1 453 ? -15.340 15.961  -25.036  1.00 42.68  ? 453 PHE B CD2   1 
ATOM   7622  C  CE1   . PHE B 1 453 ? -15.225 13.254  -25.551  1.00 42.78  ? 453 PHE B CE1   1 
ATOM   7623  C  CE2   . PHE B 1 453 ? -15.265 15.494  -26.340  1.00 46.37  ? 453 PHE B CE2   1 
ATOM   7624  C  CZ    . PHE B 1 453 ? -15.216 14.145  -26.597  1.00 45.17  ? 453 PHE B CZ    1 
ATOM   7625  N  N     . ASN B 1 454 ? -17.265 13.459  -21.011  1.00 39.44  ? 454 ASN B N     1 
ATOM   7626  C  CA    . ASN B 1 454 ? -17.893 12.154  -20.954  1.00 41.06  ? 454 ASN B CA    1 
ATOM   7627  C  C     . ASN B 1 454 ? -19.411 12.308  -20.839  1.00 40.25  ? 454 ASN B C     1 
ATOM   7628  O  O     . ASN B 1 454 ? -20.155 11.577  -21.486  1.00 40.04  ? 454 ASN B O     1 
ATOM   7629  C  CB    . ASN B 1 454 ? -17.284 11.298  -19.851  1.00 40.90  ? 454 ASN B CB    1 
ATOM   7630  C  CG    . ASN B 1 454 ? -16.029 10.615  -20.337  1.00 41.16  ? 454 ASN B CG    1 
ATOM   7631  O  OD1   . ASN B 1 454 ? -16.078 9.757   -21.214  1.00 54.49  ? 454 ASN B OD1   1 
ATOM   7632  N  ND2   . ASN B 1 454 ? -14.901 10.984  -19.778  1.00 43.11  ? 454 ASN B ND2   1 
ATOM   7633  N  N     . ILE B 1 455 ? -19.883 13.316  -20.108  1.00 40.72  ? 455 ILE B N     1 
ATOM   7634  C  CA    . ILE B 1 455 ? -21.315 13.444  -19.888  1.00 42.22  ? 455 ILE B CA    1 
ATOM   7635  C  C     . ILE B 1 455 ? -22.003 13.906  -21.174  1.00 43.34  ? 455 ILE B C     1 
ATOM   7636  O  O     . ILE B 1 455 ? -23.076 13.396  -21.535  1.00 45.53  ? 455 ILE B O     1 
ATOM   7637  C  CB    . ILE B 1 455 ? -21.611 14.335  -18.661  1.00 38.28  ? 455 ILE B CB    1 
ATOM   7638  C  CG1   . ILE B 1 455 ? -21.175 13.637  -17.372  1.00 40.19  ? 455 ILE B CG1   1 
ATOM   7639  C  CG2   . ILE B 1 455 ? -23.082 14.726  -18.586  1.00 35.27  ? 455 ILE B CG2   1 
ATOM   7640  C  CD1   . ILE B 1 455 ? -21.236 14.515  -16.124  1.00 42.01  ? 455 ILE B CD1   1 
ATOM   7641  N  N     . LEU B 1 456 ? -21.389 14.875  -21.859  1.00 36.92  ? 456 LEU B N     1 
ATOM   7642  C  CA    . LEU B 1 456 ? -21.932 15.366  -23.111  1.00 38.44  ? 456 LEU B CA    1 
ATOM   7643  C  C     . LEU B 1 456 ? -22.067 14.210  -24.100  1.00 39.37  ? 456 LEU B C     1 
ATOM   7644  O  O     . LEU B 1 456 ? -23.108 14.085  -24.751  1.00 40.22  ? 456 LEU B O     1 
ATOM   7645  C  CB    . LEU B 1 456 ? -21.038 16.464  -23.686  1.00 40.28  ? 456 LEU B CB    1 
ATOM   7646  C  CG    . LEU B 1 456 ? -20.972 17.760  -22.879  1.00 40.74  ? 456 LEU B CG    1 
ATOM   7647  C  CD1   . LEU B 1 456 ? -20.102 18.767  -23.608  1.00 40.94  ? 456 LEU B CD1   1 
ATOM   7648  C  CD2   . LEU B 1 456 ? -22.367 18.333  -22.644  1.00 41.16  ? 456 LEU B CD2   1 
ATOM   7649  N  N     . VAL B 1 457 ? -21.005 13.407  -24.237  1.00 37.41  ? 457 VAL B N     1 
ATOM   7650  C  CA    . VAL B 1 457 ? -21.030 12.270  -25.145  1.00 39.21  ? 457 VAL B CA    1 
ATOM   7651  C  C     . VAL B 1 457 ? -22.185 11.327  -24.772  1.00 35.15  ? 457 VAL B C     1 
ATOM   7652  O  O     . VAL B 1 457 ? -22.978 10.962  -25.632  1.00 35.07  ? 457 VAL B O     1 
ATOM   7653  C  CB    . VAL B 1 457 ? -19.679 11.531  -25.200  1.00 38.43  ? 457 VAL B CB    1 
ATOM   7654  C  CG1   . VAL B 1 457 ? -19.802 10.205  -25.927  1.00 38.43  ? 457 VAL B CG1   1 
ATOM   7655  C  CG2   . VAL B 1 457 ? -18.566 12.362  -25.841  1.00 42.92  ? 457 VAL B CG2   1 
ATOM   7656  N  N     . ASP B 1 458 ? -22.279 10.941  -23.492  1.00 39.81  ? 458 ASP B N     1 
ATOM   7657  C  CA    . ASP B 1 458 ? -23.268 9.975   -23.038  1.00 37.74  ? 458 ASP B CA    1 
ATOM   7658  C  C     . ASP B 1 458 ? -24.669 10.504  -23.319  1.00 41.34  ? 458 ASP B C     1 
ATOM   7659  O  O     . ASP B 1 458 ? -25.518 9.745   -23.797  1.00 41.51  ? 458 ASP B O     1 
ATOM   7660  C  CB    . ASP B 1 458 ? -23.139 9.669   -21.544  1.00 40.41  ? 458 ASP B CB    1 
ATOM   7661  C  CG    . ASP B 1 458 ? -21.864 8.955   -21.127  1.00 43.76  ? 458 ASP B CG    1 
ATOM   7662  O  OD1   . ASP B 1 458 ? -21.258 8.277   -21.980  1.00 37.18  ? 458 ASP B OD1   1 
ATOM   7663  O  OD2   . ASP B 1 458 ? -21.460 9.131   -19.960  1.00 42.01  ? 458 ASP B OD2   1 
ATOM   7664  N  N     . GLU B 1 459 ? -24.901 11.798  -23.027  1.00 39.23  ? 459 GLU B N     1 
ATOM   7665  C  CA    . GLU B 1 459 ? -26.250 12.347  -23.079  1.00 38.37  ? 459 GLU B CA    1 
ATOM   7666  C  C     . GLU B 1 459 ? -26.676 12.524  -24.534  1.00 39.74  ? 459 GLU B C     1 
ATOM   7667  O  O     . GLU B 1 459 ? -27.857 12.410  -24.868  1.00 37.48  ? 459 GLU B O     1 
ATOM   7668  C  CB    . GLU B 1 459 ? -26.374 13.635  -22.253  1.00 37.35  ? 459 GLU B CB    1 
ATOM   7669  C  CG    . GLU B 1 459 ? -26.421 13.351  -20.762  1.00 38.03  ? 459 GLU B CG    1 
ATOM   7670  C  CD    . GLU B 1 459 ? -26.500 14.504  -19.770  1.00 44.13  ? 459 GLU B CD    1 
ATOM   7671  O  OE1   . GLU B 1 459 ? -26.466 15.704  -20.173  1.00 40.76  ? 459 GLU B OE1   1 
ATOM   7672  O  OE2   . GLU B 1 459 ? -26.554 14.190  -18.557  1.00 45.73  ? 459 GLU B OE2   1 
ATOM   7673  N  N     . ALA B 1 460 ? -25.711 12.835  -25.397  1.00 44.09  ? 460 ALA B N     1 
ATOM   7674  C  CA    . ALA B 1 460 ? -26.008 13.070  -26.802  1.00 47.21  ? 460 ALA B CA    1 
ATOM   7675  C  C     . ALA B 1 460 ? -26.262 11.743  -27.523  1.00 37.10  ? 460 ALA B C     1 
ATOM   7676  O  O     . ALA B 1 460 ? -27.168 11.667  -28.334  1.00 38.94  ? 460 ALA B O     1 
ATOM   7677  C  CB    . ALA B 1 460 ? -24.894 13.865  -27.455  1.00 45.74  ? 460 ALA B CB    1 
ATOM   7678  N  N     . ALA B 1 461 ? -25.465 10.710  -27.242  1.00 42.02  ? 461 ALA B N     1 
ATOM   7679  C  CA    . ALA B 1 461 ? -25.702 9.409   -27.847  1.00 39.67  ? 461 ALA B CA    1 
ATOM   7680  C  C     . ALA B 1 461 ? -27.114 8.924   -27.519  1.00 38.03  ? 461 ALA B C     1 
ATOM   7681  O  O     . ALA B 1 461 ? -27.796 8.383   -28.374  1.00 40.53  ? 461 ALA B O     1 
ATOM   7682  C  CB    . ALA B 1 461 ? -24.653 8.419   -27.416  1.00 41.50  ? 461 ALA B CB    1 
ATOM   7683  N  N     . ALA B 1 462 ? -27.607 9.187   -26.308  1.00 42.38  ? 462 ALA B N     1 
ATOM   7684  C  CA    . ALA B 1 462 ? -28.892 8.649   -25.897  1.00 42.04  ? 462 ALA B CA    1 
ATOM   7685  C  C     . ALA B 1 462 ? -30.027 9.344   -26.642  1.00 46.83  ? 462 ALA B C     1 
ATOM   7686  O  O     . ALA B 1 462 ? -31.111 8.792   -26.755  1.00 45.24  ? 462 ALA B O     1 
ATOM   7687  C  CB    . ALA B 1 462 ? -29.052 8.792   -24.408  1.00 48.36  ? 462 ALA B CB    1 
ATOM   7688  N  N     . GLU B 1 463 ? -29.766 10.557  -27.140  1.00 43.08  ? 463 GLU B N     1 
ATOM   7689  C  CA    . GLU B 1 463 ? -30.724 11.296  -27.932  1.00 43.84  ? 463 GLU B CA    1 
ATOM   7690  C  C     . GLU B 1 463 ? -30.605 10.917  -29.400  1.00 41.14  ? 463 GLU B C     1 
ATOM   7691  O  O     . GLU B 1 463 ? -31.309 11.479  -30.227  1.00 45.23  ? 463 GLU B O     1 
ATOM   7692  C  CB    . GLU B 1 463 ? -30.493 12.801  -27.773  1.00 43.52  ? 463 GLU B CB    1 
ATOM   7693  C  CG    . GLU B 1 463 ? -30.806 13.324  -26.388  1.00 48.32  ? 463 GLU B CG    1 
ATOM   7694  C  CD    . GLU B 1 463 ? -32.154 12.945  -25.816  1.00 48.92  ? 463 GLU B CD    1 
ATOM   7695  O  OE1   . GLU B 1 463 ? -33.142 13.046  -26.547  1.00 48.22  ? 463 GLU B OE1   1 
ATOM   7696  O  OE2   . GLU B 1 463 ? -32.205 12.580  -24.619  1.00 62.39  ? 463 GLU B OE2   1 
ATOM   7697  N  N     . GLY B 1 464 ? -29.658 10.033  -29.706  1.00 41.73  ? 464 GLY B N     1 
ATOM   7698  C  CA    . GLY B 1 464 ? -29.451 9.540   -31.050  1.00 41.50  ? 464 GLY B CA    1 
ATOM   7699  C  C     . GLY B 1 464 ? -28.351 10.287  -31.806  1.00 45.25  ? 464 GLY B C     1 
ATOM   7700  O  O     . GLY B 1 464 ? -28.287 10.181  -33.024  1.00 44.23  ? 464 GLY B O     1 
ATOM   7701  N  N     . TYR B 1 465 ? -27.466 11.005  -31.097  1.00 38.37  ? 465 TYR B N     1 
ATOM   7702  C  CA    . TYR B 1 465 ? -26.471 11.807  -31.778  1.00 39.38  ? 465 TYR B CA    1 
ATOM   7703  C  C     . TYR B 1 465 ? -25.090 11.219  -31.547  1.00 36.84  ? 465 TYR B C     1 
ATOM   7704  O  O     . TYR B 1 465 ? -24.602 11.200  -30.409  1.00 38.72  ? 465 TYR B O     1 
ATOM   7705  C  CB    . TYR B 1 465 ? -26.460 13.248  -31.277  1.00 38.48  ? 465 TYR B CB    1 
ATOM   7706  C  CG    . TYR B 1 465 ? -27.806 13.896  -31.194  1.00 36.26  ? 465 TYR B CG    1 
ATOM   7707  C  CD1   . TYR B 1 465 ? -28.719 13.769  -32.223  1.00 40.55  ? 465 TYR B CD1   1 
ATOM   7708  C  CD2   . TYR B 1 465 ? -28.171 14.634  -30.072  1.00 34.69  ? 465 TYR B CD2   1 
ATOM   7709  C  CE1   . TYR B 1 465 ? -29.978 14.353  -32.152  1.00 38.43  ? 465 TYR B CE1   1 
ATOM   7710  C  CE2   . TYR B 1 465 ? -29.426 15.219  -29.991  1.00 33.43  ? 465 TYR B CE2   1 
ATOM   7711  C  CZ    . TYR B 1 465 ? -30.327 15.096  -31.038  1.00 37.77  ? 465 TYR B CZ    1 
ATOM   7712  O  OH    . TYR B 1 465 ? -31.579 15.710  -31.001  1.00 42.80  ? 465 TYR B OH    1 
ATOM   7713  N  N     . GLY B 1 466 ? -24.441 10.842  -32.651  1.00 35.35  ? 466 GLY B N     1 
ATOM   7714  C  CA    . GLY B 1 466 ? -23.161 10.155  -32.576  1.00 39.35  ? 466 GLY B CA    1 
ATOM   7715  C  C     . GLY B 1 466 ? -21.991 10.917  -33.194  1.00 31.99  ? 466 GLY B C     1 
ATOM   7716  O  O     . GLY B 1 466 ? -22.095 11.434  -34.297  1.00 36.23  ? 466 GLY B O     1 
ATOM   7717  N  N     . GLU B 1 467 ? -20.820 10.822  -32.549  1.00 35.74  ? 467 GLU B N     1 
ATOM   7718  C  CA    . GLU B 1 467 ? -19.602 11.469  -33.028  1.00 35.15  ? 467 GLU B CA    1 
ATOM   7719  C  C     . GLU B 1 467 ? -19.028 10.782  -34.277  1.00 33.25  ? 467 GLU B C     1 
ATOM   7720  O  O     . GLU B 1 467 ? -19.006 9.549   -34.416  1.00 35.31  ? 467 GLU B O     1 
ATOM   7721  C  CB    . GLU B 1 467 ? -18.583 11.480  -31.885  1.00 37.67  ? 467 GLU B CB    1 
ATOM   7722  C  CG    . GLU B 1 467 ? -17.286 12.201  -32.217  1.00 36.01  ? 467 GLU B CG    1 
ATOM   7723  C  CD    . GLU B 1 467 ? -17.394 13.687  -32.550  1.00 34.46  ? 467 GLU B CD    1 
ATOM   7724  O  OE1   . GLU B 1 467 ? -17.075 14.508  -31.668  1.00 36.55  ? 467 GLU B OE1   1 
ATOM   7725  O  OE2   . GLU B 1 467 ? -17.790 14.044  -33.702  1.00 34.41  ? 467 GLU B OE2   1 
ATOM   7726  N  N     . TYR B 1 468 ? -18.494 11.592  -35.187  1.00 35.78  ? 468 TYR B N     1 
ATOM   7727  C  CA    . TYR B 1 468 ? -17.835 11.075  -36.381  1.00 37.00  ? 468 TYR B CA    1 
ATOM   7728  C  C     . TYR B 1 468 ? -16.318 11.293  -36.320  1.00 40.22  ? 468 TYR B C     1 
ATOM   7729  O  O     . TYR B 1 468 ? -15.578 10.671  -37.093  1.00 40.27  ? 468 TYR B O     1 
ATOM   7730  C  CB    . TYR B 1 468 ? -18.425 11.702  -37.646  1.00 34.26  ? 468 TYR B CB    1 
ATOM   7731  C  CG    . TYR B 1 468 ? -17.941 13.094  -37.961  1.00 34.04  ? 468 TYR B CG    1 
ATOM   7732  C  CD1   . TYR B 1 468 ? -18.461 14.192  -37.299  1.00 37.01  ? 468 TYR B CD1   1 
ATOM   7733  C  CD2   . TYR B 1 468 ? -16.944 13.316  -38.903  1.00 32.12  ? 468 TYR B CD2   1 
ATOM   7734  C  CE1   . TYR B 1 468 ? -18.028 15.488  -37.578  1.00 36.33  ? 468 TYR B CE1   1 
ATOM   7735  C  CE2   . TYR B 1 468 ? -16.505 14.600  -39.197  1.00 35.66  ? 468 TYR B CE2   1 
ATOM   7736  C  CZ    . TYR B 1 468 ? -17.047 15.688  -38.536  1.00 37.46  ? 468 TYR B CZ    1 
ATOM   7737  O  OH    . TYR B 1 468 ? -16.629 16.962  -38.781  1.00 39.69  ? 468 TYR B OH    1 
ATOM   7738  N  N     . ARG B 1 469 ? -15.844 12.155  -35.412  1.00 38.10  ? 469 ARG B N     1 
ATOM   7739  C  CA    . ARG B 1 469 ? -14.403 12.355  -35.303  1.00 41.32  ? 469 ARG B CA    1 
ATOM   7740  C  C     . ARG B 1 469 ? -14.030 12.805  -33.898  1.00 37.69  ? 469 ARG B C     1 
ATOM   7741  O  O     . ARG B 1 469 ? -14.747 13.593  -33.299  1.00 37.42  ? 469 ARG B O     1 
ATOM   7742  C  CB    . ARG B 1 469 ? -14.007 13.405  -36.327  1.00 45.01  ? 469 ARG B CB    1 
ATOM   7743  C  CG    . ARG B 1 469 ? -12.515 13.593  -36.462  1.00 48.46  ? 469 ARG B CG    1 
ATOM   7744  C  CD    . ARG B 1 469 ? -12.296 14.769  -37.381  1.00 50.25  ? 469 ARG B CD    1 
ATOM   7745  N  NE    . ARG B 1 469 ? -10.875 15.010  -37.429  1.00 49.61  ? 469 ARG B NE    1 
ATOM   7746  C  CZ    . ARG B 1 469 ? -10.329 16.055  -38.006  1.00 45.04  ? 469 ARG B CZ    1 
ATOM   7747  N  NH1   . ARG B 1 469 ? -11.109 16.956  -38.567  1.00 41.95  ? 469 ARG B NH1   1 
ATOM   7748  N  NH2   . ARG B 1 469 ? -9.010  16.171  -38.042  1.00 48.92  ? 469 ARG B NH2   1 
ATOM   7749  N  N     . THR B 1 470 ? -12.912 12.312  -33.356  1.00 37.61  ? 470 THR B N     1 
ATOM   7750  C  CA    . THR B 1 470 ? -12.639 12.531  -31.943  1.00 41.67  ? 470 THR B CA    1 
ATOM   7751  C  C     . THR B 1 470 ? -11.144 12.470  -31.636  1.00 45.29  ? 470 THR B C     1 
ATOM   7752  O  O     . THR B 1 470 ? -10.334 12.190  -32.505  1.00 40.81  ? 470 THR B O     1 
ATOM   7753  C  CB    . THR B 1 470 ? -13.391 11.536  -31.045  1.00 43.95  ? 470 THR B CB    1 
ATOM   7754  O  OG1   . THR B 1 470 ? -13.451 12.045  -29.711  1.00 39.96  ? 470 THR B OG1   1 
ATOM   7755  C  CG2   . THR B 1 470 ? -12.765 10.155  -31.029  1.00 46.77  ? 470 THR B CG2   1 
ATOM   7756  N  N     . HIS B 1 471 ? -10.829 12.791  -30.374  1.00 43.42  ? 471 HIS B N     1 
ATOM   7757  C  CA    . HIS B 1 471 ? -9.488  12.843  -29.821  1.00 46.31  ? 471 HIS B CA    1 
ATOM   7758  C  C     . HIS B 1 471 ? -9.021  11.422  -29.493  1.00 45.01  ? 471 HIS B C     1 
ATOM   7759  O  O     . HIS B 1 471 ? -9.844  10.574  -29.141  1.00 52.49  ? 471 HIS B O     1 
ATOM   7760  C  CB    . HIS B 1 471 ? -9.565  13.762  -28.585  1.00 48.01  ? 471 HIS B CB    1 
ATOM   7761  C  CG    . HIS B 1 471 ? -8.307  13.971  -27.822  1.00 53.03  ? 471 HIS B CG    1 
ATOM   7762  N  ND1   . HIS B 1 471 ? -7.600  12.964  -27.190  1.00 53.51  ? 471 HIS B ND1   1 
ATOM   7763  C  CD2   . HIS B 1 471 ? -7.642  15.112  -27.567  1.00 61.57  ? 471 HIS B CD2   1 
ATOM   7764  C  CE1   . HIS B 1 471 ? -6.526  13.480  -26.613  1.00 52.82  ? 471 HIS B CE1   1 
ATOM   7765  N  NE2   . HIS B 1 471 ? -6.545  14.788  -26.807  1.00 57.22  ? 471 HIS B NE2   1 
ATOM   7766  N  N     . ILE B 1 472 ? -7.699  11.186  -29.502  1.00 50.20  ? 472 ILE B N     1 
ATOM   7767  C  CA    . ILE B 1 472 ? -7.114  9.867   -29.233  1.00 50.59  ? 472 ILE B CA    1 
ATOM   7768  C  C     . ILE B 1 472 ? -7.545  9.262   -27.900  1.00 56.47  ? 472 ILE B C     1 
ATOM   7769  O  O     . ILE B 1 472 ? -7.626  8.032   -27.756  1.00 56.24  ? 472 ILE B O     1 
ATOM   7770  C  CB    . ILE B 1 472 ? -5.581  9.942   -29.282  1.00 58.46  ? 472 ILE B CB    1 
ATOM   7771  C  CG1   . ILE B 1 472 ? -5.054  11.017  -28.319  1.00 57.83  ? 472 ILE B CG1   1 
ATOM   7772  C  CG2   . ILE B 1 472 ? -5.118  10.131  -30.720  1.00 53.01  ? 472 ILE B CG2   1 
ATOM   7773  C  CD1   . ILE B 1 472 ? -3.589  10.892  -28.002  1.00 56.37  ? 472 ILE B CD1   1 
ATOM   7774  N  N     . ARG B 1 473 ? -7.784  10.122  -26.912  1.00 54.27  ? 473 ARG B N     1 
ATOM   7775  C  CA    . ARG B 1 473 ? -8.259  9.670   -25.617  1.00 53.78  ? 473 ARG B CA    1 
ATOM   7776  C  C     . ARG B 1 473 ? -9.639  9.023   -25.731  1.00 50.87  ? 473 ARG B C     1 
ATOM   7777  O  O     . ARG B 1 473 ? -9.953  8.131   -24.959  1.00 51.96  ? 473 ARG B O     1 
ATOM   7778  C  CB    . ARG B 1 473 ? -8.296  10.842  -24.630  1.00 56.58  ? 473 ARG B CB    1 
ATOM   7779  C  CG    . ARG B 1 473 ? -8.887  10.508  -23.264  1.00 60.18  ? 473 ARG B CG    1 
ATOM   7780  C  CD    . ARG B 1 473 ? -8.489  11.539  -22.210  1.00 68.92  ? 473 ARG B CD    1 
ATOM   7781  N  NE    . ARG B 1 473 ? -9.011  11.294  -20.865  1.00 67.90  ? 473 ARG B NE    1 
ATOM   7782  C  CZ    . ARG B 1 473 ? -8.481  10.472  -19.964  1.00 55.98  ? 473 ARG B CZ    1 
ATOM   7783  N  NH1   . ARG B 1 473 ? -7.375  9.810   -20.220  1.00 57.03  ? 473 ARG B NH1   1 
ATOM   7784  N  NH2   . ARG B 1 473 ? -9.062  10.318  -18.792  1.00 60.82  ? 473 ARG B NH2   1 
ATOM   7785  N  N     . TYR B 1 474 ? -10.494 9.478   -26.655  1.00 48.87  ? 474 TYR B N     1 
ATOM   7786  C  CA    . TYR B 1 474 ? -11.880 9.052   -26.606  1.00 44.36  ? 474 TYR B CA    1 
ATOM   7787  C  C     . TYR B 1 474 ? -12.195 8.071   -27.741  1.00 41.45  ? 474 TYR B C     1 
ATOM   7788  O  O     . TYR B 1 474 ? -13.351 7.738   -27.968  1.00 38.04  ? 474 TYR B O     1 
ATOM   7789  C  CB    . TYR B 1 474 ? -12.787 10.288  -26.594  1.00 45.78  ? 474 TYR B CB    1 
ATOM   7790  C  CG    . TYR B 1 474 ? -12.510 11.261  -25.474  1.00 51.09  ? 474 TYR B CG    1 
ATOM   7791  C  CD1   . TYR B 1 474 ? -12.765 10.937  -24.147  1.00 52.40  ? 474 TYR B CD1   1 
ATOM   7792  C  CD2   . TYR B 1 474 ? -11.982 12.520  -25.743  1.00 54.59  ? 474 TYR B CD2   1 
ATOM   7793  C  CE1   . TYR B 1 474 ? -12.478 11.828  -23.122  1.00 51.60  ? 474 TYR B CE1   1 
ATOM   7794  C  CE2   . TYR B 1 474 ? -11.718 13.431  -24.734  1.00 49.00  ? 474 TYR B CE2   1 
ATOM   7795  C  CZ    . TYR B 1 474 ? -11.963 13.084  -23.416  1.00 51.48  ? 474 TYR B CZ    1 
ATOM   7796  O  OH    . TYR B 1 474 ? -11.690 14.001  -22.419  1.00 56.11  ? 474 TYR B OH    1 
ATOM   7797  N  N     . MET B 1 475 ? -11.179 7.587   -28.456  1.00 39.64  ? 475 MET B N     1 
ATOM   7798  C  CA    . MET B 1 475 ? -11.438 6.812   -29.659  1.00 40.84  ? 475 MET B CA    1 
ATOM   7799  C  C     . MET B 1 475 ? -12.164 5.512   -29.314  1.00 45.95  ? 475 MET B C     1 
ATOM   7800  O  O     . MET B 1 475 ? -13.038 5.076   -30.071  1.00 41.14  ? 475 MET B O     1 
ATOM   7801  C  CB    . MET B 1 475 ? -10.150 6.481   -30.403  1.00 39.29  ? 475 MET B CB    1 
ATOM   7802  C  CG    . MET B 1 475 ? -9.666  7.634   -31.202  1.00 42.74  ? 475 MET B CG    1 
ATOM   7803  S  SD    . MET B 1 475 ? -8.134  7.276   -32.058  1.00 45.93  ? 475 MET B SD    1 
ATOM   7804  C  CE    . MET B 1 475 ? -7.934  8.904   -32.790  1.00 53.98  ? 475 MET B CE    1 
ATOM   7805  N  N     . ASP B 1 476 ? -11.798 4.886   -28.191  1.00 39.47  ? 476 ASP B N     1 
ATOM   7806  C  CA    . ASP B 1 476 ? -12.537 3.709   -27.745  1.00 47.47  ? 476 ASP B CA    1 
ATOM   7807  C  C     . ASP B 1 476 ? -13.970 4.062   -27.378  1.00 46.36  ? 476 ASP B C     1 
ATOM   7808  O  O     . ASP B 1 476 ? -14.874 3.290   -27.669  1.00 43.06  ? 476 ASP B O     1 
ATOM   7809  C  CB    . ASP B 1 476 ? -11.945 3.038   -26.504  1.00 48.12  ? 476 ASP B CB    1 
ATOM   7810  C  CG    . ASP B 1 476 ? -10.894 2.009   -26.840  1.00 49.39  ? 476 ASP B CG    1 
ATOM   7811  O  OD1   . ASP B 1 476 ? -10.607 1.826   -28.040  1.00 49.25  ? 476 ASP B OD1   1 
ATOM   7812  O  OD2   . ASP B 1 476 ? -10.383 1.397   -25.899  1.00 61.01  ? 476 ASP B OD2   1 
ATOM   7813  N  N     . ARG B 1 477 ? -14.140 5.193   -26.690  1.00 42.46  ? 477 ARG B N     1 
ATOM   7814  C  CA    . ARG B 1 477 ? -15.441 5.589   -26.177  1.00 46.94  ? 477 ARG B CA    1 
ATOM   7815  C  C     . ARG B 1 477 ? -16.379 5.825   -27.363  1.00 45.44  ? 477 ARG B C     1 
ATOM   7816  O  O     . ARG B 1 477 ? -17.533 5.401   -27.349  1.00 44.11  ? 477 ARG B O     1 
ATOM   7817  C  CB    . ARG B 1 477 ? -15.278 6.792   -25.232  1.00 47.75  ? 477 ARG B CB    1 
ATOM   7818  C  CG    . ARG B 1 477 ? -16.539 7.602   -24.960  1.00 55.40  ? 477 ARG B CG    1 
ATOM   7819  C  CD    . ARG B 1 477 ? -17.563 7.027   -23.981  1.00 65.16  ? 477 ARG B CD    1 
ATOM   7820  N  NE    . ARG B 1 477 ? -18.488 6.118   -24.639  1.00 67.92  ? 477 ARG B NE    1 
ATOM   7821  C  CZ    . ARG B 1 477 ? -19.750 6.384   -24.977  1.00 69.05  ? 477 ARG B CZ    1 
ATOM   7822  N  NH1   . ARG B 1 477 ? -20.449 7.320   -24.362  1.00 67.75  ? 477 ARG B NH1   1 
ATOM   7823  N  NH2   . ARG B 1 477 ? -20.343 5.632   -25.886  1.00 70.50  ? 477 ARG B NH2   1 
ATOM   7824  N  N     . ILE B 1 478 ? -15.874 6.454   -28.426  1.00 42.60  ? 478 ILE B N     1 
ATOM   7825  C  CA    . ILE B 1 478 ? -16.732 6.745   -29.556  1.00 41.40  ? 478 ILE B CA    1 
ATOM   7826  C  C     . ILE B 1 478 ? -17.028 5.465   -30.335  1.00 40.47  ? 478 ILE B C     1 
ATOM   7827  O  O     . ILE B 1 478 ? -18.124 5.318   -30.855  1.00 37.17  ? 478 ILE B O     1 
ATOM   7828  C  CB    . ILE B 1 478 ? -16.133 7.841   -30.445  1.00 40.07  ? 478 ILE B CB    1 
ATOM   7829  C  CG1   . ILE B 1 478 ? -15.912 9.127   -29.643  1.00 38.54  ? 478 ILE B CG1   1 
ATOM   7830  C  CG2   . ILE B 1 478 ? -17.020 8.055   -31.670  1.00 40.21  ? 478 ILE B CG2   1 
ATOM   7831  C  CD1   . ILE B 1 478 ? -17.150 9.655   -28.935  1.00 38.12  ? 478 ILE B CD1   1 
ATOM   7832  N  N     . ALA B 1 479 ? -16.065 4.548   -30.427  1.00 37.30  ? 479 ALA B N     1 
ATOM   7833  C  CA    . ALA B 1 479 ? -16.301 3.263   -31.080  1.00 40.70  ? 479 ALA B CA    1 
ATOM   7834  C  C     . ALA B 1 479 ? -17.504 2.572   -30.440  1.00 43.60  ? 479 ALA B C     1 
ATOM   7835  O  O     . ALA B 1 479 ? -18.390 2.052   -31.136  1.00 44.26  ? 479 ALA B O     1 
ATOM   7836  C  CB    . ALA B 1 479 ? -15.065 2.401   -30.996  1.00 41.34  ? 479 ALA B CB    1 
ATOM   7837  N  N     . LYS B 1 480 ? -17.581 2.667   -29.106  1.00 44.03  ? 480 LYS B N     1 
ATOM   7838  C  CA    . LYS B 1 480 ? -18.610 1.974   -28.351  1.00 47.35  ? 480 LYS B CA    1 
ATOM   7839  C  C     . LYS B 1 480 ? -19.994 2.587   -28.544  1.00 43.93  ? 480 LYS B C     1 
ATOM   7840  O  O     . LYS B 1 480 ? -20.990 1.956   -28.178  1.00 43.83  ? 480 LYS B O     1 
ATOM   7841  C  CB    . LYS B 1 480 ? -18.224 1.899   -26.870  1.00 51.50  ? 480 LYS B CB    1 
ATOM   7842  C  CG    . LYS B 1 480 ? -17.018 1.019   -26.571  1.00 58.35  ? 480 LYS B CG    1 
ATOM   7843  C  CD    . LYS B 1 480 ? -16.592 1.084   -25.110  1.00 70.35  ? 480 LYS B CD    1 
ATOM   7844  C  CE    . LYS B 1 480 ? -15.144 0.708   -24.882  1.00 79.66  ? 480 LYS B CE    1 
ATOM   7845  N  NZ    . LYS B 1 480 ? -14.862 -0.657  -25.382  1.00 91.30  ? 480 LYS B NZ    1 
ATOM   7846  N  N     . THR B 1 481 ? -20.095 3.770   -29.159  1.00 41.32  ? 481 THR B N     1 
ATOM   7847  C  CA    . THR B 1 481 ? -21.411 4.295   -29.503  1.00 46.77  ? 481 THR B CA    1 
ATOM   7848  C  C     . THR B 1 481 ? -22.023 3.541   -30.688  1.00 44.16  ? 481 THR B C     1 
ATOM   7849  O  O     . THR B 1 481 ? -23.240 3.526   -30.845  1.00 38.70  ? 481 THR B O     1 
ATOM   7850  C  CB    . THR B 1 481 ? -21.362 5.805   -29.783  1.00 51.90  ? 481 THR B CB    1 
ATOM   7851  O  OG1   . THR B 1 481 ? -20.337 6.069   -30.723  1.00 66.85  ? 481 THR B OG1   1 
ATOM   7852  C  CG2   . THR B 1 481 ? -21.038 6.631   -28.566  1.00 59.68  ? 481 THR B CG2   1 
ATOM   7853  N  N     . TYR B 1 482 ? -21.177 2.908   -31.515  1.00 41.05  ? 482 TYR B N     1 
ATOM   7854  C  CA    . TYR B 1 482 ? -21.588 2.283   -32.763  1.00 42.12  ? 482 TYR B CA    1 
ATOM   7855  C  C     . TYR B 1 482 ? -21.782 0.783   -32.513  1.00 41.93  ? 482 TYR B C     1 
ATOM   7856  O  O     . TYR B 1 482 ? -21.182 -0.033  -33.198  1.00 41.43  ? 482 TYR B O     1 
ATOM   7857  C  CB    . TYR B 1 482 ? -20.571 2.639   -33.865  1.00 38.52  ? 482 TYR B CB    1 
ATOM   7858  C  CG    . TYR B 1 482 ? -20.668 4.085   -34.260  1.00 37.11  ? 482 TYR B CG    1 
ATOM   7859  C  CD1   . TYR B 1 482 ? -21.687 4.520   -35.080  1.00 34.85  ? 482 TYR B CD1   1 
ATOM   7860  C  CD2   . TYR B 1 482 ? -19.861 5.045   -33.677  1.00 40.34  ? 482 TYR B CD2   1 
ATOM   7861  C  CE1   . TYR B 1 482 ? -21.856 5.858   -35.369  1.00 36.46  ? 482 TYR B CE1   1 
ATOM   7862  C  CE2   . TYR B 1 482 ? -20.005 6.389   -33.963  1.00 36.60  ? 482 TYR B CE2   1 
ATOM   7863  C  CZ    . TYR B 1 482 ? -21.021 6.801   -34.799  1.00 38.70  ? 482 TYR B CZ    1 
ATOM   7864  O  OH    . TYR B 1 482 ? -21.204 8.135   -35.095  1.00 37.12  ? 482 TYR B OH    1 
ATOM   7865  N  N     . SER B 1 483 ? -22.702 0.465   -31.588  1.00 37.72  ? 483 SER B N     1 
ATOM   7866  C  CA    . SER B 1 483 ? -22.758 -0.810  -30.889  1.00 45.10  ? 483 SER B CA    1 
ATOM   7867  C  C     . SER B 1 483 ? -23.913 -1.698  -31.352  1.00 39.00  ? 483 SER B C     1 
ATOM   7868  O  O     . SER B 1 483 ? -24.150 -2.728  -30.735  1.00 42.83  ? 483 SER B O     1 
ATOM   7869  C  CB    . SER B 1 483 ? -22.911 -0.574  -29.413  1.00 39.92  ? 483 SER B CB    1 
ATOM   7870  O  OG    . SER B 1 483 ? -24.103 0.147   -29.193  1.00 41.24  ? 483 SER B OG    1 
ATOM   7871  N  N     . TRP B 1 484 ? -24.633 -1.307  -32.409  1.00 37.26  ? 484 TRP B N     1 
ATOM   7872  C  CA    . TRP B 1 484 ? -25.747 -2.111  -32.893  1.00 37.75  ? 484 TRP B CA    1 
ATOM   7873  C  C     . TRP B 1 484 ? -25.313 -3.564  -33.131  1.00 40.79  ? 484 TRP B C     1 
ATOM   7874  O  O     . TRP B 1 484 ? -24.273 -3.848  -33.747  1.00 37.52  ? 484 TRP B O     1 
ATOM   7875  C  CB    . TRP B 1 484 ? -26.358 -1.509  -34.156  1.00 39.16  ? 484 TRP B CB    1 
ATOM   7876  C  CG    . TRP B 1 484 ? -27.581 -2.245  -34.598  1.00 42.71  ? 484 TRP B CG    1 
ATOM   7877  C  CD1   . TRP B 1 484 ? -28.842 -2.103  -34.099  1.00 44.12  ? 484 TRP B CD1   1 
ATOM   7878  C  CD2   . TRP B 1 484 ? -27.661 -3.257  -35.620  1.00 40.77  ? 484 TRP B CD2   1 
ATOM   7879  N  NE1   . TRP B 1 484 ? -29.710 -2.930  -34.756  1.00 38.08  ? 484 TRP B NE1   1 
ATOM   7880  C  CE2   . TRP B 1 484 ? -29.014 -3.666  -35.683  1.00 44.13  ? 484 TRP B CE2   1 
ATOM   7881  C  CE3   . TRP B 1 484 ? -26.730 -3.864  -36.478  1.00 41.20  ? 484 TRP B CE3   1 
ATOM   7882  C  CZ2   . TRP B 1 484 ? -29.451 -4.673  -36.554  1.00 43.97  ? 484 TRP B CZ2   1 
ATOM   7883  C  CZ3   . TRP B 1 484 ? -27.169 -4.842  -37.354  1.00 42.48  ? 484 TRP B CZ3   1 
ATOM   7884  C  CH2   . TRP B 1 484 ? -28.507 -5.250  -37.378  1.00 43.26  ? 484 TRP B CH2   1 
ATOM   7885  N  N     . ASN B 1 485 ? -26.148 -4.468  -32.613  1.00 37.26  ? 485 ASN B N     1 
ATOM   7886  C  CA    . ASN B 1 485 ? -26.009 -5.909  -32.725  1.00 35.40  ? 485 ASN B CA    1 
ATOM   7887  C  C     . ASN B 1 485 ? -24.697 -6.350  -32.085  1.00 39.42  ? 485 ASN B C     1 
ATOM   7888  O  O     . ASN B 1 485 ? -23.820 -6.897  -32.750  1.00 41.78  ? 485 ASN B O     1 
ATOM   7889  C  CB    . ASN B 1 485 ? -26.217 -6.390  -34.159  1.00 38.74  ? 485 ASN B CB    1 
ATOM   7890  C  CG    . ASN B 1 485 ? -26.143 -7.904  -34.263  1.00 41.75  ? 485 ASN B CG    1 
ATOM   7891  O  OD1   . ASN B 1 485 ? -26.281 -8.612  -33.265  1.00 43.44  ? 485 ASN B OD1   1 
ATOM   7892  N  ND2   . ASN B 1 485 ? -25.852 -8.399  -35.448  1.00 39.92  ? 485 ASN B ND2   1 
ATOM   7893  N  N     . ASP B 1 486 ? -24.576 -6.088  -30.773  1.00 39.24  ? 486 ASP B N     1 
ATOM   7894  C  CA    . ASP B 1 486 ? -23.400 -6.451  -30.001  1.00 40.42  ? 486 ASP B CA    1 
ATOM   7895  C  C     . ASP B 1 486 ? -22.111 -6.088  -30.746  1.00 38.09  ? 486 ASP B C     1 
ATOM   7896  O  O     . ASP B 1 486 ? -21.197 -6.901  -30.830  1.00 38.51  ? 486 ASP B O     1 
ATOM   7897  C  CB    . ASP B 1 486 ? -23.443 -7.923  -29.589  1.00 42.32  ? 486 ASP B CB    1 
ATOM   7898  C  CG    . ASP B 1 486 ? -22.335 -8.310  -28.623  1.00 45.13  ? 486 ASP B CG    1 
ATOM   7899  O  OD1   . ASP B 1 486 ? -22.022 -7.507  -27.720  1.00 41.94  ? 486 ASP B OD1   1 
ATOM   7900  O  OD2   . ASP B 1 486 ? -21.781 -9.404  -28.780  1.00 50.62  ? 486 ASP B OD2   1 
ATOM   7901  N  N     . ASN B 1 487 ? -22.005 -4.833  -31.197  1.00 35.96  ? 487 ASN B N     1 
ATOM   7902  C  CA    . ASN B 1 487 ? -20.801 -4.296  -31.826  1.00 41.18  ? 487 ASN B CA    1 
ATOM   7903  C  C     . ASN B 1 487 ? -20.407 -5.063  -33.095  1.00 43.99  ? 487 ASN B C     1 
ATOM   7904  O  O     . ASN B 1 487 ? -19.225 -5.295  -33.352  1.00 38.41  ? 487 ASN B O     1 
ATOM   7905  C  CB    . ASN B 1 487 ? -19.605 -4.268  -30.871  1.00 41.48  ? 487 ASN B CB    1 
ATOM   7906  C  CG    . ASN B 1 487 ? -19.881 -3.436  -29.642  1.00 45.20  ? 487 ASN B CG    1 
ATOM   7907  O  OD1   . ASN B 1 487 ? -20.094 -3.989  -28.573  1.00 50.34  ? 487 ASN B OD1   1 
ATOM   7908  N  ND2   . ASN B 1 487 ? -19.940 -2.124  -29.788  1.00 42.24  ? 487 ASN B ND2   1 
ATOM   7909  N  N     . ALA B 1 488 ? -21.398 -5.397  -33.926  1.00 42.69  ? 488 ALA B N     1 
ATOM   7910  C  CA    . ALA B 1 488 ? -21.145 -6.188  -35.119  1.00 39.64  ? 488 ALA B CA    1 
ATOM   7911  C  C     . ALA B 1 488 ? -20.160 -5.493  -36.069  1.00 42.75  ? 488 ALA B C     1 
ATOM   7912  O  O     . ALA B 1 488 ? -19.284 -6.157  -36.638  1.00 39.14  ? 488 ALA B O     1 
ATOM   7913  C  CB    . ALA B 1 488 ? -22.433 -6.466  -35.808  1.00 38.06  ? 488 ALA B CB    1 
ATOM   7914  N  N     . LEU B 1 489 ? -20.321 -4.169  -36.254  1.00 39.69  ? 489 LEU B N     1 
ATOM   7915  C  CA    . LEU B 1 489 ? -19.485 -3.426  -37.174  1.00 36.74  ? 489 LEU B CA    1 
ATOM   7916  C  C     . LEU B 1 489 ? -18.019 -3.528  -36.753  1.00 39.29  ? 489 LEU B C     1 
ATOM   7917  O  O     . LEU B 1 489 ? -17.189 -3.824  -37.607  1.00 39.76  ? 489 LEU B O     1 
ATOM   7918  C  CB    . LEU B 1 489 ? -19.962 -1.972  -37.290  1.00 37.71  ? 489 LEU B CB    1 
ATOM   7919  C  CG    . LEU B 1 489 ? -19.139 -1.108  -38.259  1.00 37.98  ? 489 LEU B CG    1 
ATOM   7920  C  CD1   . LEU B 1 489 ? -19.113 -1.729  -39.662  1.00 41.89  ? 489 LEU B CD1   1 
ATOM   7921  C  CD2   . LEU B 1 489 ? -19.683 0.317   -38.351  1.00 38.13  ? 489 LEU B CD2   1 
ATOM   7922  N  N     . TRP B 1 490 ? -17.700 -3.309  -35.461  1.00 40.20  ? 490 TRP B N     1 
ATOM   7923  C  CA    . TRP B 1 490 ? -16.315 -3.321  -34.997  1.00 39.15  ? 490 TRP B CA    1 
ATOM   7924  C  C     . TRP B 1 490 ? -15.724 -4.732  -35.027  1.00 41.33  ? 490 TRP B C     1 
ATOM   7925  O  O     . TRP B 1 490 ? -14.531 -4.882  -35.265  1.00 38.23  ? 490 TRP B O     1 
ATOM   7926  C  CB    . TRP B 1 490 ? -16.135 -2.644  -33.629  1.00 38.13  ? 490 TRP B CB    1 
ATOM   7927  C  CG    . TRP B 1 490 ? -15.464 -1.309  -33.758  1.00 36.53  ? 490 TRP B CG    1 
ATOM   7928  C  CD1   . TRP B 1 490 ? -14.198 -0.978  -33.377  1.00 45.30  ? 490 TRP B CD1   1 
ATOM   7929  C  CD2   . TRP B 1 490 ? -15.991 -0.142  -34.403  1.00 37.02  ? 490 TRP B CD2   1 
ATOM   7930  N  NE1   . TRP B 1 490 ? -13.911 0.320   -33.715  1.00 43.57  ? 490 TRP B NE1   1 
ATOM   7931  C  CE2   . TRP B 1 490 ? -14.993 0.859   -34.349  1.00 38.96  ? 490 TRP B CE2   1 
ATOM   7932  C  CE3   . TRP B 1 490 ? -17.208 0.158   -35.016  1.00 40.16  ? 490 TRP B CE3   1 
ATOM   7933  C  CZ2   . TRP B 1 490 ? -15.178 2.133   -34.888  1.00 37.28  ? 490 TRP B CZ2   1 
ATOM   7934  C  CZ3   . TRP B 1 490 ? -17.398 1.424   -35.531  1.00 40.62  ? 490 TRP B CZ3   1 
ATOM   7935  C  CH2   . TRP B 1 490 ? -16.391 2.390   -35.484  1.00 38.62  ? 490 TRP B CH2   1 
ATOM   7936  N  N     . LYS B 1 491 ? -16.557 -5.761  -34.848  1.00 40.35  ? 491 LYS B N     1 
ATOM   7937  C  CA    . LYS B 1 491 ? -16.120 -7.136  -35.055  1.00 43.23  ? 491 LYS B CA    1 
ATOM   7938  C  C     . LYS B 1 491 ? -15.703 -7.349  -36.516  1.00 41.00  ? 491 LYS B C     1 
ATOM   7939  O  O     . LYS B 1 491 ? -14.729 -8.038  -36.796  1.00 44.93  ? 491 LYS B O     1 
ATOM   7940  C  CB    . LYS B 1 491 ? -17.232 -8.102  -34.642  1.00 45.10  ? 491 LYS B CB    1 
ATOM   7941  C  CG    . LYS B 1 491 ? -17.390 -8.302  -33.140  1.00 44.49  ? 491 LYS B CG    1 
ATOM   7942  C  CD    . LYS B 1 491 ? -18.690 -9.002  -32.815  1.00 48.64  ? 491 LYS B CD    1 
ATOM   7943  C  CE    . LYS B 1 491 ? -18.972 -9.124  -31.327  1.00 51.02  ? 491 LYS B CE    1 
ATOM   7944  N  NZ    . LYS B 1 491 ? -20.332 -9.666  -31.101  1.00 52.90  ? 491 LYS B NZ    1 
ATOM   7945  N  N     . MET B 1 492 ? -16.387 -6.700  -37.456  1.00 40.91  ? 492 MET B N     1 
ATOM   7946  C  CA    . MET B 1 492 ? -15.934 -6.751  -38.836  1.00 38.96  ? 492 MET B CA    1 
ATOM   7947  C  C     . MET B 1 492 ? -14.631 -5.952  -39.016  1.00 42.23  ? 492 MET B C     1 
ATOM   7948  O  O     . MET B 1 492 ? -13.701 -6.427  -39.673  1.00 38.56  ? 492 MET B O     1 
ATOM   7949  C  CB    . MET B 1 492 ? -17.007 -6.244  -39.794  1.00 40.72  ? 492 MET B CB    1 
ATOM   7950  C  CG    . MET B 1 492 ? -16.747 -6.634  -41.239  1.00 39.21  ? 492 MET B CG    1 
ATOM   7951  S  SD    . MET B 1 492 ? -17.674 -5.624  -42.366  1.00 45.50  ? 492 MET B SD    1 
ATOM   7952  C  CE    . MET B 1 492 ? -16.821 -4.071  -42.125  1.00 46.26  ? 492 MET B CE    1 
ATOM   7953  N  N     . HIS B 1 493 ? -14.512 -4.770  -38.396  1.00 40.80  ? 493 HIS B N     1 
ATOM   7954  C  CA    . HIS B 1 493 ? -13.287 -3.998  -38.526  1.00 42.73  ? 493 HIS B CA    1 
ATOM   7955  C  C     . HIS B 1 493 ? -12.101 -4.816  -38.020  1.00 41.62  ? 493 HIS B C     1 
ATOM   7956  O  O     . HIS B 1 493 ? -11.041 -4.782  -38.636  1.00 41.86  ? 493 HIS B O     1 
ATOM   7957  C  CB    . HIS B 1 493 ? -13.335 -2.663  -37.772  1.00 40.56  ? 493 HIS B CB    1 
ATOM   7958  C  CG    . HIS B 1 493 ? -14.226 -1.666  -38.383  1.00 41.38  ? 493 HIS B CG    1 
ATOM   7959  N  ND1   . HIS B 1 493 ? -14.418 -1.599  -39.742  1.00 43.34  ? 493 HIS B ND1   1 
ATOM   7960  C  CD2   . HIS B 1 493 ? -14.982 -0.699  -37.853  1.00 38.67  ? 493 HIS B CD2   1 
ATOM   7961  C  CE1   . HIS B 1 493 ? -15.277 -0.622  -40.009  1.00 42.16  ? 493 HIS B CE1   1 
ATOM   7962  N  NE2   . HIS B 1 493 ? -15.636 -0.071  -38.875  1.00 38.81  ? 493 HIS B NE2   1 
ATOM   7963  N  N     . GLU B 1 494 ? -12.293 -5.508  -36.881  1.00 42.21  ? 494 GLU B N     1 
ATOM   7964  C  CA    . GLU B 1 494 ? -11.262 -6.304  -36.232  1.00 44.13  ? 494 GLU B CA    1 
ATOM   7965  C  C     . GLU B 1 494 ? -10.844 -7.479  -37.122  1.00 42.92  ? 494 GLU B C     1 
ATOM   7966  O  O     . GLU B 1 494 ? -9.688  -7.882  -37.103  1.00 41.94  ? 494 GLU B O     1 
ATOM   7967  C  CB    . GLU B 1 494 ? -11.721 -6.797  -34.847  1.00 45.27  ? 494 GLU B CB    1 
ATOM   7968  C  CG    . GLU B 1 494 ? -11.776 -5.706  -33.750  1.00 53.61  ? 494 GLU B CG    1 
ATOM   7969  C  CD    . GLU B 1 494 ? -10.469 -5.162  -33.163  1.00 58.99  ? 494 GLU B CD    1 
ATOM   7970  O  OE1   . GLU B 1 494 ? -9.373  -5.607  -33.573  1.00 55.64  ? 494 GLU B OE1   1 
ATOM   7971  O  OE2   . GLU B 1 494 ? -10.538 -4.268  -32.280  1.00 68.47  ? 494 GLU B OE2   1 
ATOM   7972  N  N     . THR B 1 495 ? -11.793 -8.048  -37.860  1.00 42.74  ? 495 THR B N     1 
ATOM   7973  C  CA    . THR B 1 495 ? -11.526 -9.149  -38.773  1.00 46.23  ? 495 THR B CA    1 
ATOM   7974  C  C     . THR B 1 495 ? -10.629 -8.666  -39.906  1.00 44.96  ? 495 THR B C     1 
ATOM   7975  O  O     . THR B 1 495 ? -9.698  -9.350  -40.302  1.00 37.01  ? 495 THR B O     1 
ATOM   7976  C  CB    . THR B 1 495 ? -12.836 -9.734  -39.325  1.00 44.45  ? 495 THR B CB    1 
ATOM   7977  O  OG1   . THR B 1 495 ? -13.557 -10.280 -38.221  1.00 43.85  ? 495 THR B OG1   1 
ATOM   7978  C  CG2   . THR B 1 495 ? -12.644 -10.820 -40.362  1.00 43.16  ? 495 THR B CG2   1 
ATOM   7979  N  N     . ILE B 1 496 ? -10.927 -7.476  -40.431  1.00 44.60  ? 496 ILE B N     1 
ATOM   7980  C  CA    . ILE B 1 496 ? -10.141 -6.919  -41.516  1.00 41.11  ? 496 ILE B CA    1 
ATOM   7981  C  C     . ILE B 1 496 ? -8.768  -6.542  -40.980  1.00 43.52  ? 496 ILE B C     1 
ATOM   7982  O  O     . ILE B 1 496 ? -7.773  -6.660  -41.690  1.00 46.43  ? 496 ILE B O     1 
ATOM   7983  C  CB    . ILE B 1 496 ? -10.884 -5.737  -42.161  1.00 40.64  ? 496 ILE B CB    1 
ATOM   7984  C  CG1   . ILE B 1 496 ? -12.191 -6.233  -42.797  1.00 44.18  ? 496 ILE B CG1   1 
ATOM   7985  C  CG2   . ILE B 1 496 ? -9.989  -5.000  -43.140  1.00 40.47  ? 496 ILE B CG2   1 
ATOM   7986  C  CD1   . ILE B 1 496 ? -13.042 -5.188  -43.443  1.00 43.88  ? 496 ILE B CD1   1 
ATOM   7987  N  N     . LYS B 1 497 ? -8.721  -6.117  -39.716  1.00 44.29  ? 497 LYS B N     1 
ATOM   7988  C  CA    . LYS B 1 497 ? -7.469  -5.715  -39.103  1.00 47.10  ? 497 LYS B CA    1 
ATOM   7989  C  C     . LYS B 1 497 ? -6.527  -6.914  -38.976  1.00 45.64  ? 497 LYS B C     1 
ATOM   7990  O  O     . LYS B 1 497 ? -5.331  -6.791  -39.226  1.00 43.13  ? 497 LYS B O     1 
ATOM   7991  C  CB    . LYS B 1 497 ? -7.743  -5.081  -37.741  1.00 46.29  ? 497 LYS B CB    1 
ATOM   7992  C  CG    . LYS B 1 497 ? -6.504  -4.677  -36.957  1.00 47.74  ? 497 LYS B CG    1 
ATOM   7993  C  CD    . LYS B 1 497 ? -5.656  -3.644  -37.631  1.00 49.70  ? 497 LYS B CD    1 
ATOM   7994  C  CE    . LYS B 1 497 ? -4.684  -3.020  -36.657  1.00 53.06  ? 497 LYS B CE    1 
ATOM   7995  N  NZ    . LYS B 1 497 ? -3.721  -2.130  -37.343  1.00 55.44  ? 497 LYS B NZ    1 
ATOM   7996  N  N     . ASP B 1 498 ? -7.064  -8.064  -38.562  1.00 46.46  ? 498 ASP B N     1 
ATOM   7997  C  CA    . ASP B 1 498 ? -6.258  -9.260  -38.367  1.00 47.02  ? 498 ASP B CA    1 
ATOM   7998  C  C     . ASP B 1 498 ? -5.818  -9.837  -39.712  1.00 45.41  ? 498 ASP B C     1 
ATOM   7999  O  O     . ASP B 1 498 ? -4.730  -10.374 -39.816  1.00 50.17  ? 498 ASP B O     1 
ATOM   8000  C  CB    . ASP B 1 498 ? -6.996  -10.280 -37.503  1.00 45.90  ? 498 ASP B CB    1 
ATOM   8001  C  CG    . ASP B 1 498 ? -7.219  -9.796  -36.080  1.00 46.21  ? 498 ASP B CG    1 
ATOM   8002  O  OD1   . ASP B 1 498 ? -6.482  -8.900  -35.640  1.00 46.47  ? 498 ASP B OD1   1 
ATOM   8003  O  OD2   . ASP B 1 498 ? -8.174  -10.280 -35.441  1.00 52.66  ? 498 ASP B OD2   1 
ATOM   8004  N  N     . ALA B 1 499 ? -6.626  -9.670  -40.757  1.00 45.77  ? 499 ALA B N     1 
ATOM   8005  C  CA    . ALA B 1 499 ? -6.252  -10.126 -42.086  1.00 45.38  ? 499 ALA B CA    1 
ATOM   8006  C  C     . ALA B 1 499 ? -5.081  -9.311  -42.632  1.00 46.29  ? 499 ALA B C     1 
ATOM   8007  O  O     . ALA B 1 499 ? -4.112  -9.895  -43.094  1.00 44.69  ? 499 ALA B O     1 
ATOM   8008  C  CB    . ALA B 1 499 ? -7.433  -10.028 -43.010  1.00 47.34  ? 499 ALA B CB    1 
ATOM   8009  N  N     . LEU B 1 500 ? -5.178  -7.967  -42.572  1.00 45.25  ? 500 LEU B N     1 
ATOM   8010  C  CA    . LEU B 1 500 ? -4.216  -7.075  -43.207  1.00 40.73  ? 500 LEU B CA    1 
ATOM   8011  C  C     . LEU B 1 500 ? -2.993  -6.857  -42.331  1.00 43.41  ? 500 LEU B C     1 
ATOM   8012  O  O     . LEU B 1 500 ? -1.916  -6.588  -42.862  1.00 47.79  ? 500 LEU B O     1 
ATOM   8013  C  CB    . LEU B 1 500 ? -4.852  -5.714  -43.484  1.00 41.66  ? 500 LEU B CB    1 
ATOM   8014  C  CG    . LEU B 1 500 ? -5.955  -5.677  -44.528  1.00 45.64  ? 500 LEU B CG    1 
ATOM   8015  C  CD1   . LEU B 1 500 ? -6.460  -4.257  -44.669  1.00 47.10  ? 500 LEU B CD1   1 
ATOM   8016  C  CD2   . LEU B 1 500 ? -5.476  -6.206  -45.879  1.00 45.55  ? 500 LEU B CD2   1 
ATOM   8017  N  N     . ASP B 1 501 ? -3.172  -6.901  -41.003  1.00 43.03  ? 501 ASP B N     1 
ATOM   8018  C  CA    . ASP B 1 501 ? -2.115  -6.570  -40.061  1.00 42.73  ? 501 ASP B CA    1 
ATOM   8019  C  C     . ASP B 1 501 ? -2.017  -7.632  -38.972  1.00 41.72  ? 501 ASP B C     1 
ATOM   8020  O  O     . ASP B 1 501 ? -2.172  -7.334  -37.797  1.00 43.94  ? 501 ASP B O     1 
ATOM   8021  C  CB    . ASP B 1 501 ? -2.392  -5.210  -39.421  1.00 44.59  ? 501 ASP B CB    1 
ATOM   8022  C  CG    . ASP B 1 501 ? -1.282  -4.667  -38.546  1.00 46.65  ? 501 ASP B CG    1 
ATOM   8023  O  OD1   . ASP B 1 501 ? -0.171  -5.236  -38.587  1.00 51.56  ? 501 ASP B OD1   1 
ATOM   8024  O  OD2   . ASP B 1 501 ? -1.532  -3.659  -37.838  1.00 48.37  ? 501 ASP B OD2   1 
ATOM   8025  N  N     . PRO B 1 502 ? -1.731  -8.904  -39.312  1.00 48.19  ? 502 PRO B N     1 
ATOM   8026  C  CA    . PRO B 1 502 ? -1.621  -9.965  -38.309  1.00 49.11  ? 502 PRO B CA    1 
ATOM   8027  C  C     . PRO B 1 502 ? -0.851  -9.607  -37.036  1.00 54.30  ? 502 PRO B C     1 
ATOM   8028  O  O     . PRO B 1 502 ? -1.230  -10.048 -35.957  1.00 55.98  ? 502 PRO B O     1 
ATOM   8029  C  CB    . PRO B 1 502 ? -0.856  -11.072 -39.050  1.00 50.86  ? 502 PRO B CB    1 
ATOM   8030  C  CG    . PRO B 1 502 ? -1.183  -10.869 -40.507  1.00 50.50  ? 502 PRO B CG    1 
ATOM   8031  C  CD    . PRO B 1 502 ? -1.487  -9.394  -40.678  1.00 50.98  ? 502 PRO B CD    1 
ATOM   8032  N  N     . ASN B 1 503 ? 0.227   -8.815  -37.155  1.00 46.88  ? 503 ASN B N     1 
ATOM   8033  C  CA    . ASN B 1 503 ? 1.103   -8.574  -36.021  1.00 46.32  ? 503 ASN B CA    1 
ATOM   8034  C  C     . ASN B 1 503 ? 0.637   -7.381  -35.204  1.00 48.68  ? 503 ASN B C     1 
ATOM   8035  O  O     . ASN B 1 503 ? 1.180   -7.149  -34.139  1.00 55.03  ? 503 ASN B O     1 
ATOM   8036  C  CB    . ASN B 1 503 ? 2.562   -8.394  -36.445  1.00 48.23  ? 503 ASN B CB    1 
ATOM   8037  C  CG    . ASN B 1 503 ? 3.100   -9.640  -37.108  1.00 48.82  ? 503 ASN B CG    1 
ATOM   8038  O  OD1   . ASN B 1 503 ? 2.736   -10.748 -36.728  1.00 50.82  ? 503 ASN B OD1   1 
ATOM   8039  N  ND2   . ASN B 1 503 ? 3.902   -9.477  -38.145  1.00 52.39  ? 503 ASN B ND2   1 
ATOM   8040  N  N     . GLY B 1 504 ? -0.383  -6.663  -35.679  1.00 48.60  ? 504 GLY B N     1 
ATOM   8041  C  CA    . GLY B 1 504 ? -0.883  -5.489  -34.991  1.00 45.01  ? 504 GLY B CA    1 
ATOM   8042  C  C     . GLY B 1 504 ? 0.171   -4.391  -34.879  1.00 45.48  ? 504 GLY B C     1 
ATOM   8043  O  O     . GLY B 1 504 ? 0.308   -3.772  -33.833  1.00 55.32  ? 504 GLY B O     1 
ATOM   8044  N  N     . ILE B 1 505 ? 0.917   -4.111  -35.941  1.00 43.63  ? 505 ILE B N     1 
ATOM   8045  C  CA    . ILE B 1 505 ? 1.949   -3.091  -35.807  1.00 50.47  ? 505 ILE B CA    1 
ATOM   8046  C  C     . ILE B 1 505 ? 1.464   -1.697  -36.236  1.00 50.57  ? 505 ILE B C     1 
ATOM   8047  O  O     . ILE B 1 505 ? 2.130   -0.707  -35.921  1.00 52.55  ? 505 ILE B O     1 
ATOM   8048  C  CB    . ILE B 1 505 ? 3.278   -3.516  -36.461  1.00 51.02  ? 505 ILE B CB    1 
ATOM   8049  C  CG1   . ILE B 1 505 ? 3.130   -4.080  -37.877  1.00 53.85  ? 505 ILE B CG1   1 
ATOM   8050  C  CG2   . ILE B 1 505 ? 3.964   -4.523  -35.548  1.00 53.80  ? 505 ILE B CG2   1 
ATOM   8051  C  CD1   . ILE B 1 505 ? 2.643   -3.087  -38.885  1.00 57.54  ? 505 ILE B CD1   1 
ATOM   8052  N  N     . LEU B 1 506 ? 0.282   -1.576  -36.854  1.00 46.71  ? 506 LEU B N     1 
ATOM   8053  C  CA    . LEU B 1 506 ? -0.187  -0.255  -37.268  1.00 48.63  ? 506 LEU B CA    1 
ATOM   8054  C  C     . LEU B 1 506 ? -1.180  0.317   -36.266  1.00 46.01  ? 506 LEU B C     1 
ATOM   8055  O  O     . LEU B 1 506 ? -2.281  -0.208  -36.095  1.00 50.95  ? 506 LEU B O     1 
ATOM   8056  C  CB    . LEU B 1 506 ? -0.819  -0.337  -38.665  1.00 54.67  ? 506 LEU B CB    1 
ATOM   8057  C  CG    . LEU B 1 506 ? 0.155   -0.292  -39.842  1.00 53.53  ? 506 LEU B CG    1 
ATOM   8058  C  CD1   . LEU B 1 506 ? -0.554  0.114   -41.125  1.00 49.22  ? 506 LEU B CD1   1 
ATOM   8059  C  CD2   . LEU B 1 506 ? 1.319   0.658   -39.569  1.00 55.48  ? 506 LEU B CD2   1 
ATOM   8060  N  N     . ALA B 1 507 ? -0.754  1.405   -35.615  1.00 50.42  ? 507 ALA B N     1 
ATOM   8061  C  CA    . ALA B 1 507 ? -1.587  2.284   -34.799  1.00 45.71  ? 507 ALA B CA    1 
ATOM   8062  C  C     . ALA B 1 507 ? -2.621  1.511   -33.965  1.00 51.42  ? 507 ALA B C     1 
ATOM   8063  O  O     . ALA B 1 507 ? -3.838  1.741   -34.072  1.00 41.60  ? 507 ALA B O     1 
ATOM   8064  C  CB    . ALA B 1 507 ? -2.232  3.320   -35.691  1.00 42.46  ? 507 ALA B CB    1 
ATOM   8065  N  N     . PRO B 1 508 ? -2.167  0.620   -33.053  1.00 51.44  ? 508 PRO B N     1 
ATOM   8066  C  CA    . PRO B 1 508 ? -3.074  -0.110  -32.176  1.00 51.87  ? 508 PRO B CA    1 
ATOM   8067  C  C     . PRO B 1 508 ? -3.968  0.885   -31.458  1.00 51.00  ? 508 PRO B C     1 
ATOM   8068  O  O     . PRO B 1 508 ? -3.468  1.819   -30.836  1.00 57.90  ? 508 PRO B O     1 
ATOM   8069  C  CB    . PRO B 1 508 ? -2.159  -0.813  -31.163  1.00 55.77  ? 508 PRO B CB    1 
ATOM   8070  C  CG    . PRO B 1 508 ? -0.835  -0.933  -31.891  1.00 58.26  ? 508 PRO B CG    1 
ATOM   8071  C  CD    . PRO B 1 508 ? -0.759  0.293   -32.787  1.00 51.85  ? 508 PRO B CD    1 
ATOM   8072  N  N     . GLY B 1 509 ? -5.283  0.686   -31.588  1.00 45.05  ? 509 GLY B N     1 
ATOM   8073  C  CA    . GLY B 1 509 ? -6.256  1.512   -30.898  1.00 39.02  ? 509 GLY B CA    1 
ATOM   8074  C  C     . GLY B 1 509 ? -6.819  2.653   -31.740  1.00 39.89  ? 509 GLY B C     1 
ATOM   8075  O  O     . GLY B 1 509 ? -7.689  3.361   -31.253  1.00 43.83  ? 509 GLY B O     1 
ATOM   8076  N  N     . LYS B 1 510 ? -6.328  2.864   -32.973  1.00 41.22  ? 510 LYS B N     1 
ATOM   8077  C  CA    . LYS B 1 510 ? -6.925  3.871   -33.845  1.00 40.92  ? 510 LYS B CA    1 
ATOM   8078  C  C     . LYS B 1 510 ? -8.386  3.490   -34.080  1.00 38.67  ? 510 LYS B C     1 
ATOM   8079  O  O     . LYS B 1 510 ? -8.686  2.319   -34.335  1.00 37.15  ? 510 LYS B O     1 
ATOM   8080  C  CB    . LYS B 1 510 ? -6.112  4.029   -35.138  1.00 42.61  ? 510 LYS B CB    1 
ATOM   8081  C  CG    . LYS B 1 510 ? -6.624  5.044   -36.152  1.00 44.97  ? 510 LYS B CG    1 
ATOM   8082  C  CD    . LYS B 1 510 ? -6.904  6.451   -35.650  1.00 46.36  ? 510 LYS B CD    1 
ATOM   8083  C  CE    . LYS B 1 510 ? -7.398  7.351   -36.765  1.00 51.35  ? 510 LYS B CE    1 
ATOM   8084  N  NZ    . LYS B 1 510 ? -8.167  8.537   -36.305  1.00 54.24  ? 510 LYS B NZ    1 
ATOM   8085  N  N     . SER B 1 511 ? -9.279  4.484   -33.925  1.00 40.37  ? 511 SER B N     1 
ATOM   8086  C  CA    . SER B 1 511 ? -10.729 4.325   -34.016  1.00 39.05  ? 511 SER B CA    1 
ATOM   8087  C  C     . SER B 1 511 ? -11.260 3.153   -33.190  1.00 40.02  ? 511 SER B C     1 
ATOM   8088  O  O     . SER B 1 511 ? -12.265 2.555   -33.565  1.00 43.41  ? 511 SER B O     1 
ATOM   8089  C  CB    . SER B 1 511 ? -11.171 4.140   -35.445  1.00 42.76  ? 511 SER B CB    1 
ATOM   8090  O  OG    . SER B 1 511 ? -10.738 5.191   -36.271  1.00 37.41  ? 511 SER B OG    1 
ATOM   8091  N  N     . GLY B 1 512 ? -10.630 2.851   -32.051  1.00 42.33  ? 512 GLY B N     1 
ATOM   8092  C  CA    . GLY B 1 512 ? -11.018 1.711   -31.228  1.00 41.03  ? 512 GLY B CA    1 
ATOM   8093  C  C     . GLY B 1 512 ? -10.748 0.339   -31.855  1.00 39.81  ? 512 GLY B C     1 
ATOM   8094  O  O     . GLY B 1 512 ? -11.353 -0.631  -31.420  1.00 42.57  ? 512 GLY B O     1 
ATOM   8095  N  N     . ILE B 1 513 ? -9.834  0.253   -32.843  1.00 40.62  ? 513 ILE B N     1 
ATOM   8096  C  CA    . ILE B 1 513 ? -9.494  -0.990  -33.527  1.00 41.02  ? 513 ILE B CA    1 
ATOM   8097  C  C     . ILE B 1 513 ? -8.123  -1.459  -33.055  1.00 44.93  ? 513 ILE B C     1 
ATOM   8098  O  O     . ILE B 1 513 ? -7.113  -0.796  -33.330  1.00 44.33  ? 513 ILE B O     1 
ATOM   8099  C  CB    . ILE B 1 513 ? -9.488  -0.826  -35.059  1.00 42.02  ? 513 ILE B CB    1 
ATOM   8100  C  CG1   . ILE B 1 513 ? -10.819 -0.295  -35.606  1.00 44.95  ? 513 ILE B CG1   1 
ATOM   8101  C  CG2   . ILE B 1 513 ? -9.091  -2.134  -35.720  1.00 41.24  ? 513 ILE B CG2   1 
ATOM   8102  C  CD1   . ILE B 1 513 ? -10.702 0.352   -36.981  1.00 43.93  ? 513 ILE B CD1   1 
ATOM   8103  N  N     . TRP B 1 514 ? -8.092  -2.636  -32.399  1.00 43.90  ? 514 TRP B N     1 
ATOM   8104  C  CA    . TRP B 1 514 ? -6.935  -3.032  -31.608  1.00 47.45  ? 514 TRP B CA    1 
ATOM   8105  C  C     . TRP B 1 514 ? -6.133  -4.173  -32.240  1.00 47.99  ? 514 TRP B C     1 
ATOM   8106  O  O     . TRP B 1 514 ? -4.910  -4.234  -32.103  1.00 57.95  ? 514 TRP B O     1 
ATOM   8107  C  CB    . TRP B 1 514 ? -7.369  -3.329  -30.162  1.00 45.55  ? 514 TRP B CB    1 
ATOM   8108  C  CG    . TRP B 1 514 ? -7.568  -2.066  -29.384  1.00 44.44  ? 514 TRP B CG    1 
ATOM   8109  C  CD1   . TRP B 1 514 ? -8.738  -1.396  -29.180  1.00 44.34  ? 514 TRP B CD1   1 
ATOM   8110  C  CD2   . TRP B 1 514 ? -6.549  -1.299  -28.728  1.00 40.38  ? 514 TRP B CD2   1 
ATOM   8111  N  NE1   . TRP B 1 514 ? -8.516  -0.266  -28.435  1.00 47.84  ? 514 TRP B NE1   1 
ATOM   8112  C  CE2   . TRP B 1 514 ? -7.183  -0.181  -28.146  1.00 42.72  ? 514 TRP B CE2   1 
ATOM   8113  C  CE3   . TRP B 1 514 ? -5.163  -1.454  -28.569  1.00 44.47  ? 514 TRP B CE3   1 
ATOM   8114  C  CZ2   . TRP B 1 514 ? -6.474  0.785   -27.438  1.00 41.30  ? 514 TRP B CZ2   1 
ATOM   8115  C  CZ3   . TRP B 1 514 ? -4.460  -0.502  -27.863  1.00 41.59  ? 514 TRP B CZ3   1 
ATOM   8116  C  CH2   . TRP B 1 514 ? -5.114  0.603   -27.305  1.00 45.71  ? 514 TRP B CH2   1 
ATOM   8117  N  N     . GLY B 1 515 ? -6.795  -5.112  -32.888  1.00 46.18  ? 515 GLY B N     1 
ATOM   8118  C  CA    . GLY B 1 515 ? -6.069  -6.267  -33.388  1.00 50.66  ? 515 GLY B CA    1 
ATOM   8119  C  C     . GLY B 1 515 ? -5.971  -7.360  -32.322  1.00 44.93  ? 515 GLY B C     1 
ATOM   8120  O  O     . GLY B 1 515 ? -5.983  -7.071  -31.135  1.00 44.26  ? 515 GLY B O     1 
ATOM   8121  N  N     . LYS B 1 516 ? -5.905  -8.605  -32.793  1.00 45.21  ? 516 LYS B N     1 
ATOM   8122  C  CA    . LYS B 1 516 ? -5.916  -9.828  -32.006  1.00 49.01  ? 516 LYS B CA    1 
ATOM   8123  C  C     . LYS B 1 516 ? -4.918  -9.791  -30.857  1.00 46.96  ? 516 LYS B C     1 
ATOM   8124  O  O     . LYS B 1 516 ? -5.250  -10.210 -29.761  1.00 48.82  ? 516 LYS B O     1 
ATOM   8125  C  CB    . LYS B 1 516 ? -5.565  -10.958 -32.972  1.00 59.38  ? 516 LYS B CB    1 
ATOM   8126  C  CG    . LYS B 1 516 ? -5.601  -12.389 -32.459  1.00 70.44  ? 516 LYS B CG    1 
ATOM   8127  C  CD    . LYS B 1 516 ? -5.283  -13.385 -33.584  1.00 77.37  ? 516 LYS B CD    1 
ATOM   8128  C  CE    . LYS B 1 516 ? -4.325  -12.819 -34.620  1.00 77.19  ? 516 LYS B CE    1 
ATOM   8129  N  NZ    . LYS B 1 516 ? -3.974  -13.805 -35.664  1.00 82.57  ? 516 LYS B NZ    1 
ATOM   8130  N  N     . ASN B 1 517 ? -3.699  -9.284  -31.081  1.00 50.33  ? 517 ASN B N     1 
ATOM   8131  C  CA    . ASN B 1 517 ? -2.681  -9.355  -30.048  1.00 55.03  ? 517 ASN B CA    1 
ATOM   8132  C  C     . ASN B 1 517 ? -3.033  -8.513  -28.825  1.00 57.97  ? 517 ASN B C     1 
ATOM   8133  O  O     . ASN B 1 517 ? -2.370  -8.667  -27.810  1.00 59.57  ? 517 ASN B O     1 
ATOM   8134  C  CB    . ASN B 1 517 ? -1.304  -8.889  -30.523  1.00 53.16  ? 517 ASN B CB    1 
ATOM   8135  C  CG    . ASN B 1 517 ? -0.717  -9.801  -31.570  1.00 54.01  ? 517 ASN B CG    1 
ATOM   8136  O  OD1   . ASN B 1 517 ? -0.940  -11.006 -31.538  1.00 61.52  ? 517 ASN B OD1   1 
ATOM   8137  N  ND2   . ASN B 1 517 ? -0.009  -9.234  -32.529  1.00 61.58  ? 517 ASN B ND2   1 
ATOM   8138  N  N     . ARG B 1 518 ? -4.014  -7.601  -28.923  1.00 59.97  ? 518 ARG B N     1 
ATOM   8139  C  CA    . ARG B 1 518 ? -4.248  -6.630  -27.861  1.00 58.63  ? 518 ARG B CA    1 
ATOM   8140  C  C     . ARG B 1 518 ? -5.730  -6.473  -27.501  1.00 59.90  ? 518 ARG B C     1 
ATOM   8141  O  O     . ARG B 1 518 ? -6.039  -5.729  -26.579  1.00 56.59  ? 518 ARG B O     1 
ATOM   8142  C  CB    . ARG B 1 518 ? -3.688  -5.257  -28.270  1.00 58.68  ? 518 ARG B CB    1 
ATOM   8143  C  CG    . ARG B 1 518 ? -2.168  -5.184  -28.362  1.00 59.03  ? 518 ARG B CG    1 
ATOM   8144  C  CD    . ARG B 1 518 ? -1.699  -3.779  -28.667  1.00 59.68  ? 518 ARG B CD    1 
ATOM   8145  N  NE    . ARG B 1 518 ? -0.300  -3.662  -29.079  1.00 63.45  ? 518 ARG B NE    1 
ATOM   8146  C  CZ    . ARG B 1 518 ? 0.747   -3.808  -28.270  1.00 73.42  ? 518 ARG B CZ    1 
ATOM   8147  N  NH1   . ARG B 1 518 ? 0.557   -4.160  -27.011  1.00 79.23  ? 518 ARG B NH1   1 
ATOM   8148  N  NH2   . ARG B 1 518 ? 1.979   -3.612  -28.714  1.00 68.38  ? 518 ARG B NH2   1 
ATOM   8149  N  N     . ARG B 1 519 ? -6.651  -7.119  -28.224  1.00 55.06  ? 519 ARG B N     1 
ATOM   8150  C  CA    . ARG B 1 519 ? -8.073  -6.953  -27.958  1.00 59.40  ? 519 ARG B CA    1 
ATOM   8151  C  C     . ARG B 1 519 ? -8.409  -7.385  -26.527  1.00 57.74  ? 519 ARG B C     1 
ATOM   8152  O  O     . ARG B 1 519 ? -8.335  -8.591  -26.308  1.00 58.61  ? 519 ARG B O     1 
ATOM   8153  C  CB    . ARG B 1 519 ? -8.915  -7.772  -28.936  1.00 55.53  ? 519 ARG B CB    1 
ATOM   8154  C  CG    . ARG B 1 519 ? -9.376  -6.980  -30.144  1.00 56.80  ? 519 ARG B CG    1 
ATOM   8155  C  CD    . ARG B 1 519 ? -10.496 -7.716  -30.856  1.00 60.91  ? 519 ARG B CD    1 
ATOM   8156  N  NE    . ARG B 1 519 ? -10.113 -9.033  -31.361  1.00 54.37  ? 519 ARG B NE    1 
ATOM   8157  C  CZ    . ARG B 1 519 ? -9.458  -9.258  -32.500  1.00 58.00  ? 519 ARG B CZ    1 
ATOM   8158  N  NH1   . ARG B 1 519 ? -9.015  -8.257  -33.244  1.00 56.82  ? 519 ARG B NH1   1 
ATOM   8159  N  NH2   . ARG B 1 519 ? -9.220  -10.499 -32.890  1.00 55.91  ? 519 ARG B NH2   1 
ATOM   8160  N  N     . ALA C 1 2   ? -28.664 -29.297 -68.713  1.00 79.51  ? 2   ALA C N     1 
ATOM   8161  C  CA    . ALA C 1 2   ? -28.646 -29.238 -67.230  1.00 80.72  ? 2   ALA C CA    1 
ATOM   8162  C  C     . ALA C 1 2   ? -27.324 -28.640 -66.759  1.00 85.67  ? 2   ALA C C     1 
ATOM   8163  O  O     . ALA C 1 2   ? -26.272 -28.927 -67.327  1.00 77.66  ? 2   ALA C O     1 
ATOM   8164  C  CB    . ALA C 1 2   ? -28.854 -30.614 -66.641  1.00 70.25  ? 2   ALA C CB    1 
ATOM   8165  N  N     . ALA C 1 3   ? -27.388 -27.822 -65.703  1.00 88.75  ? 3   ALA C N     1 
ATOM   8166  C  CA    . ALA C 1 3   ? -26.192 -27.265 -65.088  1.00 83.58  ? 3   ALA C CA    1 
ATOM   8167  C  C     . ALA C 1 3   ? -25.491 -28.316 -64.220  1.00 72.54  ? 3   ALA C C     1 
ATOM   8168  O  O     . ALA C 1 3   ? -26.122 -29.202 -63.644  1.00 66.27  ? 3   ALA C O     1 
ATOM   8169  C  CB    . ALA C 1 3   ? -26.559 -26.040 -64.286  1.00 92.26  ? 3   ALA C CB    1 
ATOM   8170  N  N     . PRO C 1 4   ? -24.145 -28.270 -64.115  1.00 64.36  ? 4   PRO C N     1 
ATOM   8171  C  CA    . PRO C 1 4   ? -23.411 -29.185 -63.243  1.00 66.06  ? 4   PRO C CA    1 
ATOM   8172  C  C     . PRO C 1 4   ? -23.287 -28.701 -61.798  1.00 68.08  ? 4   PRO C C     1 
ATOM   8173  O  O     . PRO C 1 4   ? -23.515 -27.524 -61.523  1.00 68.53  ? 4   PRO C O     1 
ATOM   8174  C  CB    . PRO C 1 4   ? -22.032 -29.229 -63.922  1.00 65.47  ? 4   PRO C CB    1 
ATOM   8175  C  CG    . PRO C 1 4   ? -21.859 -27.860 -64.569  1.00 64.41  ? 4   PRO C CG    1 
ATOM   8176  C  CD    . PRO C 1 4   ? -23.260 -27.366 -64.871  1.00 69.11  ? 4   PRO C CD    1 
ATOM   8177  N  N     . LEU C 1 5   ? -22.907 -29.622 -60.897  1.00 62.95  ? 5   LEU C N     1 
ATOM   8178  C  CA    . LEU C 1 5   ? -22.533 -29.297 -59.529  1.00 68.72  ? 5   LEU C CA    1 
ATOM   8179  C  C     . LEU C 1 5   ? -21.317 -28.378 -59.557  1.00 77.23  ? 5   LEU C C     1 
ATOM   8180  O  O     . LEU C 1 5   ? -20.520 -28.440 -60.488  1.00 80.68  ? 5   LEU C O     1 
ATOM   8181  C  CB    . LEU C 1 5   ? -22.199 -30.573 -58.744  1.00 68.39  ? 5   LEU C CB    1 
ATOM   8182  C  CG    . LEU C 1 5   ? -23.374 -31.484 -58.384  1.00 69.69  ? 5   LEU C CG    1 
ATOM   8183  C  CD1   . LEU C 1 5   ? -22.913 -32.680 -57.564  1.00 69.80  ? 5   LEU C CD1   1 
ATOM   8184  C  CD2   . LEU C 1 5   ? -24.445 -30.727 -57.620  1.00 73.37  ? 5   LEU C CD2   1 
ATOM   8185  N  N     . PRO C 1 6   ? -21.134 -27.493 -58.549  1.00 75.52  ? 6   PRO C N     1 
ATOM   8186  C  CA    . PRO C 1 6   ? -19.907 -26.709 -58.453  1.00 69.96  ? 6   PRO C CA    1 
ATOM   8187  C  C     . PRO C 1 6   ? -18.801 -27.667 -58.033  1.00 68.24  ? 6   PRO C C     1 
ATOM   8188  O  O     . PRO C 1 6   ? -19.076 -28.650 -57.355  1.00 63.43  ? 6   PRO C O     1 
ATOM   8189  C  CB    . PRO C 1 6   ? -20.215 -25.620 -57.417  1.00 69.99  ? 6   PRO C CB    1 
ATOM   8190  C  CG    . PRO C 1 6   ? -21.423 -26.130 -56.634  1.00 71.18  ? 6   PRO C CG    1 
ATOM   8191  C  CD    . PRO C 1 6   ? -22.092 -27.198 -57.473  1.00 72.93  ? 6   PRO C CD    1 
ATOM   8192  N  N     . GLU C 1 7   ? -17.568 -27.389 -58.468  1.00 69.26  ? 7   GLU C N     1 
ATOM   8193  C  CA    . GLU C 1 7   ? -16.471 -28.309 -58.241  1.00 70.23  ? 7   GLU C CA    1 
ATOM   8194  C  C     . GLU C 1 7   ? -16.161 -28.366 -56.750  1.00 67.44  ? 7   GLU C C     1 
ATOM   8195  O  O     . GLU C 1 7   ? -16.147 -27.340 -56.084  1.00 67.43  ? 7   GLU C O     1 
ATOM   8196  C  CB    . GLU C 1 7   ? -15.233 -27.898 -59.038  1.00 79.87  ? 7   GLU C CB    1 
ATOM   8197  C  CG    . GLU C 1 7   ? -14.065 -28.853 -58.848  1.00 83.49  ? 7   GLU C CG    1 
ATOM   8198  C  CD    . GLU C 1 7   ? -12.939 -28.651 -59.845  1.00 91.03  ? 7   GLU C CD    1 
ATOM   8199  O  OE1   . GLU C 1 7   ? -12.012 -29.493 -59.880  1.00 93.10  ? 7   GLU C OE1   1 
ATOM   8200  O  OE2   . GLU C 1 7   ? -12.994 -27.650 -60.583  1.00 91.81  ? 7   GLU C OE2   1 
ATOM   8201  N  N     . GLY C 1 8   ? -15.925 -29.579 -56.242  1.00 63.22  ? 8   GLY C N     1 
ATOM   8202  C  CA    . GLY C 1 8   ? -15.617 -29.785 -54.836  1.00 68.93  ? 8   GLY C CA    1 
ATOM   8203  C  C     . GLY C 1 8   ? -16.859 -30.021 -53.978  1.00 65.32  ? 8   GLY C C     1 
ATOM   8204  O  O     . GLY C 1 8   ? -16.726 -30.331 -52.800  1.00 66.60  ? 8   GLY C O     1 
ATOM   8205  N  N     . VAL C 1 9   ? -18.053 -29.892 -54.575  1.00 64.33  ? 9   VAL C N     1 
ATOM   8206  C  CA    . VAL C 1 9   ? -19.317 -30.004 -53.864  1.00 62.73  ? 9   VAL C CA    1 
ATOM   8207  C  C     . VAL C 1 9   ? -20.064 -31.239 -54.362  1.00 69.20  ? 9   VAL C C     1 
ATOM   8208  O  O     . VAL C 1 9   ? -20.408 -31.327 -55.540  1.00 67.39  ? 9   VAL C O     1 
ATOM   8209  C  CB    . VAL C 1 9   ? -20.173 -28.741 -54.070  1.00 65.57  ? 9   VAL C CB    1 
ATOM   8210  C  CG1   . VAL C 1 9   ? -21.605 -28.921 -53.573  1.00 60.63  ? 9   VAL C CG1   1 
ATOM   8211  C  CG2   . VAL C 1 9   ? -19.513 -27.521 -53.438  1.00 66.09  ? 9   VAL C CG2   1 
ATOM   8212  N  N     . SER C 1 10  ? -20.371 -32.158 -53.441  1.00 71.96  ? 10  SER C N     1 
ATOM   8213  C  CA    . SER C 1 10  ? -20.982 -33.425 -53.803  1.00 65.37  ? 10  SER C CA    1 
ATOM   8214  C  C     . SER C 1 10  ? -22.473 -33.236 -54.068  1.00 71.75  ? 10  SER C C     1 
ATOM   8215  O  O     . SER C 1 10  ? -23.021 -32.144 -53.906  1.00 70.41  ? 10  SER C O     1 
ATOM   8216  C  CB    . SER C 1 10  ? -20.763 -34.457 -52.726  1.00 67.20  ? 10  SER C CB    1 
ATOM   8217  O  OG    . SER C 1 10  ? -21.794 -34.391 -51.749  1.00 68.84  ? 10  SER C OG    1 
ATOM   8218  N  N     . ALA C 1 11  ? -23.120 -34.337 -54.466  1.00 70.94  ? 11  ALA C N     1 
ATOM   8219  C  CA    . ALA C 1 11  ? -24.550 -34.365 -54.699  1.00 67.86  ? 11  ALA C CA    1 
ATOM   8220  C  C     . ALA C 1 11  ? -25.284 -34.395 -53.366  1.00 66.58  ? 11  ALA C C     1 
ATOM   8221  O  O     . ALA C 1 11  ? -26.354 -33.820 -53.237  1.00 69.11  ? 11  ALA C O     1 
ATOM   8222  C  CB    . ALA C 1 11  ? -24.904 -35.567 -55.530  1.00 68.15  ? 11  ALA C CB    1 
ATOM   8223  N  N     . GLU C 1 12  ? -24.718 -35.087 -52.376  1.00 79.04  ? 12  GLU C N     1 
ATOM   8224  C  CA    . GLU C 1 12  ? -25.390 -35.220 -51.093  1.00 84.57  ? 12  GLU C CA    1 
ATOM   8225  C  C     . GLU C 1 12  ? -25.230 -33.927 -50.290  1.00 83.52  ? 12  GLU C C     1 
ATOM   8226  O  O     . GLU C 1 12  ? -26.130 -33.556 -49.540  1.00 80.18  ? 12  GLU C O     1 
ATOM   8227  C  CB    . GLU C 1 12  ? -24.880 -36.452 -50.343  1.00 89.56  ? 12  GLU C CB    1 
ATOM   8228  C  CG    . GLU C 1 12  ? -25.233 -37.761 -51.042  1.00 97.18  ? 12  GLU C CG    1 
ATOM   8229  C  CD    . GLU C 1 12  ? -25.105 -39.024 -50.202  1.00 99.11  ? 12  GLU C CD    1 
ATOM   8230  O  OE1   . GLU C 1 12  ? -24.890 -38.900 -48.977  1.00 96.87  ? 12  GLU C OE1   1 
ATOM   8231  O  OE2   . GLU C 1 12  ? -25.222 -40.134 -50.774  1.00 95.64  ? 12  GLU C OE2   1 
ATOM   8232  N  N     . ALA C 1 13  ? -24.082 -33.251 -50.443  1.00 81.47  ? 13  ALA C N     1 
ATOM   8233  C  CA    . ALA C 1 13  ? -23.887 -31.921 -49.886  1.00 68.26  ? 13  ALA C CA    1 
ATOM   8234  C  C     . ALA C 1 13  ? -24.923 -30.967 -50.473  1.00 68.22  ? 13  ALA C C     1 
ATOM   8235  O  O     . ALA C 1 13  ? -25.696 -30.365 -49.734  1.00 73.22  ? 13  ALA C O     1 
ATOM   8236  C  CB    . ALA C 1 13  ? -22.483 -31.443 -50.153  1.00 73.82  ? 13  ALA C CB    1 
ATOM   8237  N  N     . MET C 1 14  ? -24.980 -30.878 -51.806  1.00 61.29  ? 14  MET C N     1 
ATOM   8238  C  CA    . MET C 1 14  ? -25.906 -29.969 -52.461  1.00 63.54  ? 14  MET C CA    1 
ATOM   8239  C  C     . MET C 1 14  ? -27.342 -30.367 -52.128  1.00 66.97  ? 14  MET C C     1 
ATOM   8240  O  O     . MET C 1 14  ? -28.219 -29.515 -52.010  1.00 74.58  ? 14  MET C O     1 
ATOM   8241  C  CB    . MET C 1 14  ? -25.700 -29.971 -53.978  1.00 61.58  ? 14  MET C CB    1 
ATOM   8242  C  CG    . MET C 1 14  ? -26.702 -29.131 -54.757  1.00 64.33  ? 14  MET C CG    1 
ATOM   8243  S  SD    . MET C 1 14  ? -26.578 -27.330 -54.478  1.00 63.85  ? 14  MET C SD    1 
ATOM   8244  C  CE    . MET C 1 14  ? -25.075 -26.984 -55.394  1.00 56.72  ? 14  MET C CE    1 
ATOM   8245  N  N     . SER C 1 15  ? -27.575 -31.666 -51.945  1.00 64.85  ? 15  SER C N     1 
ATOM   8246  C  CA    . SER C 1 15  ? -28.911 -32.171 -51.675  1.00 67.45  ? 15  SER C CA    1 
ATOM   8247  C  C     . SER C 1 15  ? -29.413 -31.643 -50.332  1.00 60.96  ? 15  SER C C     1 
ATOM   8248  O  O     . SER C 1 15  ? -30.488 -31.044 -50.244  1.00 59.71  ? 15  SER C O     1 
ATOM   8249  C  CB    . SER C 1 15  ? -28.902 -33.691 -51.738  1.00 75.89  ? 15  SER C CB    1 
ATOM   8250  O  OG    . SER C 1 15  ? -30.053 -34.258 -51.134  1.00 76.91  ? 15  SER C OG    1 
ATOM   8251  N  N     . SER C 1 16  ? -28.601 -31.864 -49.292  1.00 58.15  ? 16  SER C N     1 
ATOM   8252  C  CA    . SER C 1 16  ? -28.929 -31.460 -47.939  1.00 64.85  ? 16  SER C CA    1 
ATOM   8253  C  C     . SER C 1 16  ? -29.070 -29.941 -47.823  1.00 72.44  ? 16  SER C C     1 
ATOM   8254  O  O     . SER C 1 16  ? -29.852 -29.451 -47.010  1.00 73.72  ? 16  SER C O     1 
ATOM   8255  C  CB    . SER C 1 16  ? -27.880 -31.966 -46.995  1.00 71.95  ? 16  SER C CB    1 
ATOM   8256  O  OG    . SER C 1 16  ? -27.532 -33.304 -47.297  1.00 74.44  ? 16  SER C OG    1 
ATOM   8257  N  N     . ALA C 1 17  ? -28.287 -29.184 -48.601  1.00 73.02  ? 17  ALA C N     1 
ATOM   8258  C  CA    . ALA C 1 17  ? -28.285 -27.735 -48.460  1.00 73.76  ? 17  ALA C CA    1 
ATOM   8259  C  C     . ALA C 1 17  ? -29.581 -27.153 -49.016  1.00 69.56  ? 17  ALA C C     1 
ATOM   8260  O  O     . ALA C 1 17  ? -30.172 -26.284 -48.375  1.00 66.08  ? 17  ALA C O     1 
ATOM   8261  C  CB    . ALA C 1 17  ? -27.071 -27.136 -49.122  1.00 78.15  ? 17  ALA C CB    1 
ATOM   8262  N  N     . LEU C 1 18  ? -30.015 -27.652 -50.191  1.00 64.38  ? 18  LEU C N     1 
ATOM   8263  C  CA    . LEU C 1 18  ? -31.245 -27.199 -50.829  1.00 63.49  ? 18  LEU C CA    1 
ATOM   8264  C  C     . LEU C 1 18  ? -32.433 -27.554 -49.939  1.00 66.43  ? 18  LEU C C     1 
ATOM   8265  O  O     . LEU C 1 18  ? -33.431 -26.843 -49.881  1.00 62.19  ? 18  LEU C O     1 
ATOM   8266  C  CB    . LEU C 1 18  ? -31.401 -27.885 -52.190  1.00 68.96  ? 18  LEU C CB    1 
ATOM   8267  C  CG    . LEU C 1 18  ? -30.354 -27.564 -53.255  1.00 72.77  ? 18  LEU C CG    1 
ATOM   8268  C  CD1   . LEU C 1 18  ? -30.677 -28.297 -54.542  1.00 75.34  ? 18  LEU C CD1   1 
ATOM   8269  C  CD2   . LEU C 1 18  ? -30.263 -26.069 -53.520  1.00 76.86  ? 18  LEU C CD2   1 
ATOM   8270  N  N     . ASP C 1 19  ? -32.298 -28.704 -49.280  1.00 70.03  ? 19  ASP C N     1 
ATOM   8271  C  CA    . ASP C 1 19  ? -33.238 -29.171 -48.282  1.00 71.38  ? 19  ASP C CA    1 
ATOM   8272  C  C     . ASP C 1 19  ? -33.421 -28.074 -47.229  1.00 65.92  ? 19  ASP C C     1 
ATOM   8273  O  O     . ASP C 1 19  ? -34.527 -27.576 -47.035  1.00 58.92  ? 19  ASP C O     1 
ATOM   8274  C  CB    . ASP C 1 19  ? -32.721 -30.505 -47.729  1.00 75.39  ? 19  ASP C CB    1 
ATOM   8275  C  CG    . ASP C 1 19  ? -33.680 -31.233 -46.815  1.00 84.13  ? 19  ASP C CG    1 
ATOM   8276  O  OD1   . ASP C 1 19  ? -34.639 -31.814 -47.339  1.00 95.04  ? 19  ASP C OD1   1 
ATOM   8277  O  OD2   . ASP C 1 19  ? -33.454 -31.207 -45.590  1.00 88.74  ? 19  ASP C OD2   1 
ATOM   8278  N  N     . ARG C 1 20  ? -32.319 -27.683 -46.572  1.00 71.15  ? 20  ARG C N     1 
ATOM   8279  C  CA    . ARG C 1 20  ? -32.358 -26.721 -45.478  1.00 63.19  ? 20  ARG C CA    1 
ATOM   8280  C  C     . ARG C 1 20  ? -32.805 -25.342 -45.965  1.00 59.58  ? 20  ARG C C     1 
ATOM   8281  O  O     . ARG C 1 20  ? -33.459 -24.629 -45.208  1.00 58.51  ? 20  ARG C O     1 
ATOM   8282  C  CB    . ARG C 1 20  ? -31.011 -26.683 -44.756  1.00 69.07  ? 20  ARG C CB    1 
ATOM   8283  C  CG    . ARG C 1 20  ? -30.924 -27.688 -43.614  1.00 82.64  ? 20  ARG C CG    1 
ATOM   8284  C  CD    . ARG C 1 20  ? -29.507 -27.959 -43.155  1.00 89.98  ? 20  ARG C CD    1 
ATOM   8285  N  NE    . ARG C 1 20  ? -29.384 -29.092 -42.245  1.00 99.71  ? 20  ARG C NE    1 
ATOM   8286  C  CZ    . ARG C 1 20  ? -29.580 -30.373 -42.570  1.00 99.39  ? 20  ARG C CZ    1 
ATOM   8287  N  NH1   . ARG C 1 20  ? -30.014 -30.715 -43.772  1.00 92.40  ? 20  ARG C NH1   1 
ATOM   8288  N  NH2   . ARG C 1 20  ? -29.351 -31.320 -41.676  1.00 96.91  ? 20  ARG C NH2   1 
ATOM   8289  N  N     . PHE C 1 21  ? -32.495 -24.981 -47.223  1.00 55.93  ? 21  PHE C N     1 
ATOM   8290  C  CA    . PHE C 1 21  ? -32.996 -23.735 -47.788  1.00 56.44  ? 21  PHE C CA    1 
ATOM   8291  C  C     . PHE C 1 21  ? -34.520 -23.743 -47.803  1.00 56.72  ? 21  PHE C C     1 
ATOM   8292  O  O     . PHE C 1 21  ? -35.157 -22.744 -47.478  1.00 50.91  ? 21  PHE C O     1 
ATOM   8293  C  CB    . PHE C 1 21  ? -32.521 -23.485 -49.224  1.00 54.24  ? 21  PHE C CB    1 
ATOM   8294  C  CG    . PHE C 1 21  ? -31.035 -23.316 -49.429  1.00 50.18  ? 21  PHE C CG    1 
ATOM   8295  C  CD1   . PHE C 1 21  ? -30.174 -23.080 -48.374  1.00 50.42  ? 21  PHE C CD1   1 
ATOM   8296  C  CD2   . PHE C 1 21  ? -30.501 -23.404 -50.705  1.00 54.96  ? 21  PHE C CD2   1 
ATOM   8297  C  CE1   . PHE C 1 21  ? -28.810 -22.934 -48.584  1.00 52.98  ? 21  PHE C CE1   1 
ATOM   8298  C  CE2   . PHE C 1 21  ? -29.136 -23.270 -50.916  1.00 57.84  ? 21  PHE C CE2   1 
ATOM   8299  C  CZ    . PHE C 1 21  ? -28.291 -23.036 -49.856  1.00 55.42  ? 21  PHE C CZ    1 
ATOM   8300  N  N     . ALA C 1 22  ? -35.105 -24.871 -48.220  1.00 67.91  ? 22  ALA C N     1 
ATOM   8301  C  CA    . ALA C 1 22  ? -36.553 -24.976 -48.354  1.00 62.77  ? 22  ALA C CA    1 
ATOM   8302  C  C     . ALA C 1 22  ? -37.235 -24.873 -46.988  1.00 52.61  ? 22  ALA C C     1 
ATOM   8303  O  O     . ALA C 1 22  ? -38.307 -24.279 -46.886  1.00 59.18  ? 22  ALA C O     1 
ATOM   8304  C  CB    . ALA C 1 22  ? -36.918 -26.255 -49.073  1.00 70.71  ? 22  ALA C CB    1 
ATOM   8305  N  N     . ARG C 1 23  ? -36.623 -25.429 -45.935  1.00 58.18  ? 23  ARG C N     1 
ATOM   8306  C  CA    . ARG C 1 23  ? -37.128 -25.204 -44.587  1.00 64.10  ? 23  ARG C CA    1 
ATOM   8307  C  C     . ARG C 1 23  ? -37.054 -23.718 -44.231  1.00 59.43  ? 23  ARG C C     1 
ATOM   8308  O  O     . ARG C 1 23  ? -37.943 -23.219 -43.550  1.00 58.02  ? 23  ARG C O     1 
ATOM   8309  C  CB    . ARG C 1 23  ? -36.370 -26.002 -43.521  1.00 75.58  ? 23  ARG C CB    1 
ATOM   8310  C  CG    . ARG C 1 23  ? -36.723 -27.478 -43.452  1.00 93.03  ? 23  ARG C CG    1 
ATOM   8311  C  CD    . ARG C 1 23  ? -36.013 -28.120 -42.274  1.00 104.47 ? 23  ARG C CD    1 
ATOM   8312  N  NE    . ARG C 1 23  ? -35.223 -29.270 -42.696  1.00 120.23 ? 23  ARG C NE    1 
ATOM   8313  C  CZ    . ARG C 1 23  ? -34.327 -29.891 -41.935  1.00 126.59 ? 23  ARG C CZ    1 
ATOM   8314  N  NH1   . ARG C 1 23  ? -34.206 -29.566 -40.660  1.00 127.44 ? 23  ARG C NH1   1 
ATOM   8315  N  NH2   . ARG C 1 23  ? -33.567 -30.848 -42.447  1.00 124.87 ? 23  ARG C NH2   1 
ATOM   8316  N  N     . ILE C 1 24  ? -36.002 -23.013 -44.667  1.00 53.58  ? 24  ILE C N     1 
ATOM   8317  C  CA    . ILE C 1 24  ? -35.830 -21.613 -44.293  1.00 53.31  ? 24  ILE C CA    1 
ATOM   8318  C  C     . ILE C 1 24  ? -36.850 -20.737 -45.018  1.00 49.66  ? 24  ILE C C     1 
ATOM   8319  O  O     . ILE C 1 24  ? -37.528 -19.963 -44.364  1.00 54.26  ? 24  ILE C O     1 
ATOM   8320  C  CB    . ILE C 1 24  ? -34.377 -21.132 -44.499  1.00 53.65  ? 24  ILE C CB    1 
ATOM   8321  C  CG1   . ILE C 1 24  ? -33.438 -21.854 -43.533  1.00 47.09  ? 24  ILE C CG1   1 
ATOM   8322  C  CG2   . ILE C 1 24  ? -34.270 -19.607 -44.362  1.00 51.23  ? 24  ILE C CG2   1 
ATOM   8323  C  CD1   . ILE C 1 24  ? -32.000 -21.939 -43.994  1.00 51.69  ? 24  ILE C CD1   1 
ATOM   8324  N  N     . VAL C 1 25  ? -36.997 -20.870 -46.344  1.00 53.78  ? 25  VAL C N     1 
ATOM   8325  C  CA    . VAL C 1 25  ? -37.805 -19.928 -47.109  1.00 50.54  ? 25  VAL C CA    1 
ATOM   8326  C  C     . VAL C 1 25  ? -39.160 -20.528 -47.481  1.00 52.71  ? 25  VAL C C     1 
ATOM   8327  O  O     . VAL C 1 25  ? -40.045 -19.808 -47.940  1.00 45.05  ? 25  VAL C O     1 
ATOM   8328  C  CB    . VAL C 1 25  ? -37.070 -19.441 -48.380  1.00 52.18  ? 25  VAL C CB    1 
ATOM   8329  C  CG1   . VAL C 1 25  ? -35.777 -18.706 -48.031  1.00 53.00  ? 25  VAL C CG1   1 
ATOM   8330  C  CG2   . VAL C 1 25  ? -36.794 -20.570 -49.362  1.00 55.44  ? 25  VAL C CG2   1 
ATOM   8331  N  N     . GLY C 1 26  ? -39.285 -21.855 -47.371  1.00 59.67  ? 26  GLY C N     1 
ATOM   8332  C  CA    . GLY C 1 26  ? -40.436 -22.553 -47.912  1.00 59.88  ? 26  GLY C CA    1 
ATOM   8333  C  C     . GLY C 1 26  ? -40.144 -23.179 -49.270  1.00 68.02  ? 26  GLY C C     1 
ATOM   8334  O  O     . GLY C 1 26  ? -39.553 -22.546 -50.146  1.00 70.37  ? 26  GLY C O     1 
ATOM   8335  N  N     . ALA C 1 27  ? -40.637 -24.412 -49.447  1.00 63.61  ? 27  ALA C N     1 
ATOM   8336  C  CA    . ALA C 1 27  ? -40.378 -25.188 -50.640  1.00 58.88  ? 27  ALA C CA    1 
ATOM   8337  C  C     . ALA C 1 27  ? -40.823 -24.411 -51.872  1.00 53.26  ? 27  ALA C C     1 
ATOM   8338  O  O     . ALA C 1 27  ? -40.245 -24.590 -52.926  1.00 53.39  ? 27  ALA C O     1 
ATOM   8339  C  CB    . ALA C 1 27  ? -41.043 -26.541 -50.538  1.00 62.54  ? 27  ALA C CB    1 
ATOM   8340  N  N     . ASP C 1 28  ? -41.808 -23.519 -51.741  1.00 55.89  ? 28  ASP C N     1 
ATOM   8341  C  CA    . ASP C 1 28  ? -42.258 -22.690 -52.855  1.00 59.89  ? 28  ASP C CA    1 
ATOM   8342  C  C     . ASP C 1 28  ? -41.156 -21.773 -53.407  1.00 57.23  ? 28  ASP C C     1 
ATOM   8343  O  O     . ASP C 1 28  ? -41.282 -21.215 -54.498  1.00 51.21  ? 28  ASP C O     1 
ATOM   8344  C  CB    . ASP C 1 28  ? -43.406 -21.775 -52.416  1.00 63.62  ? 28  ASP C CB    1 
ATOM   8345  C  CG    . ASP C 1 28  ? -44.461 -22.487 -51.590  1.00 78.48  ? 28  ASP C CG    1 
ATOM   8346  O  OD1   . ASP C 1 28  ? -45.388 -23.052 -52.204  1.00 76.38  ? 28  ASP C OD1   1 
ATOM   8347  O  OD2   . ASP C 1 28  ? -44.305 -22.526 -50.338  1.00 81.77  ? 28  ASP C OD2   1 
ATOM   8348  N  N     . TRP C 1 29  ? -40.107 -21.523 -52.626  1.00 55.15  ? 29  TRP C N     1 
ATOM   8349  C  CA    . TRP C 1 29  ? -39.175 -20.472 -52.997  1.00 56.72  ? 29  TRP C CA    1 
ATOM   8350  C  C     . TRP C 1 29  ? -37.775 -21.038 -53.209  1.00 60.13  ? 29  TRP C C     1 
ATOM   8351  O  O     . TRP C 1 29  ? -36.799 -20.305 -53.076  1.00 59.50  ? 29  TRP C O     1 
ATOM   8352  C  CB    . TRP C 1 29  ? -39.210 -19.367 -51.939  1.00 53.22  ? 29  TRP C CB    1 
ATOM   8353  C  CG    . TRP C 1 29  ? -40.561 -18.727 -51.858  1.00 46.39  ? 29  TRP C CG    1 
ATOM   8354  C  CD1   . TRP C 1 29  ? -41.473 -18.847 -50.843  1.00 43.99  ? 29  TRP C CD1   1 
ATOM   8355  C  CD2   . TRP C 1 29  ? -41.180 -17.910 -52.865  1.00 47.84  ? 29  TRP C CD2   1 
ATOM   8356  N  NE1   . TRP C 1 29  ? -42.607 -18.143 -51.142  1.00 48.25  ? 29  TRP C NE1   1 
ATOM   8357  C  CE2   . TRP C 1 29  ? -42.454 -17.547 -52.370  1.00 49.16  ? 29  TRP C CE2   1 
ATOM   8358  C  CE3   . TRP C 1 29  ? -40.788 -17.455 -54.130  1.00 52.77  ? 29  TRP C CE3   1 
ATOM   8359  C  CZ2   . TRP C 1 29  ? -43.325 -16.745 -53.096  1.00 50.93  ? 29  TRP C CZ2   1 
ATOM   8360  C  CZ3   . TRP C 1 29  ? -41.650 -16.658 -54.848  1.00 55.14  ? 29  TRP C CZ3   1 
ATOM   8361  C  CH2   . TRP C 1 29  ? -42.903 -16.310 -54.334  1.00 58.77  ? 29  TRP C CH2   1 
ATOM   8362  N  N     . VAL C 1 30  ? -37.700 -22.346 -53.504  1.00 56.52  ? 30  VAL C N     1 
ATOM   8363  C  CA    . VAL C 1 30  ? -36.498 -22.963 -54.044  1.00 59.72  ? 30  VAL C CA    1 
ATOM   8364  C  C     . VAL C 1 30  ? -36.805 -23.412 -55.471  1.00 61.61  ? 30  VAL C C     1 
ATOM   8365  O  O     . VAL C 1 30  ? -37.791 -24.097 -55.708  1.00 61.92  ? 30  VAL C O     1 
ATOM   8366  C  CB    . VAL C 1 30  ? -36.009 -24.151 -53.199  1.00 56.12  ? 30  VAL C CB    1 
ATOM   8367  C  CG1   . VAL C 1 30  ? -34.783 -24.800 -53.827  1.00 57.21  ? 30  VAL C CG1   1 
ATOM   8368  C  CG2   . VAL C 1 30  ? -35.733 -23.748 -51.759  1.00 56.89  ? 30  VAL C CG2   1 
ATOM   8369  N  N     . PHE C 1 31  ? -35.967 -22.991 -56.415  1.00 59.68  ? 31  PHE C N     1 
ATOM   8370  C  CA    . PHE C 1 31  ? -36.144 -23.312 -57.817  1.00 55.60  ? 31  PHE C CA    1 
ATOM   8371  C  C     . PHE C 1 31  ? -34.968 -24.202 -58.213  1.00 67.50  ? 31  PHE C C     1 
ATOM   8372  O  O     . PHE C 1 31  ? -33.834 -23.921 -57.824  1.00 64.93  ? 31  PHE C O     1 
ATOM   8373  C  CB    . PHE C 1 31  ? -36.316 -22.012 -58.607  1.00 53.90  ? 31  PHE C CB    1 
ATOM   8374  C  CG    . PHE C 1 31  ? -37.355 -21.094 -58.022  1.00 59.19  ? 31  PHE C CG    1 
ATOM   8375  C  CD1   . PHE C 1 31  ? -38.707 -21.319 -58.238  1.00 64.55  ? 31  PHE C CD1   1 
ATOM   8376  C  CD2   . PHE C 1 31  ? -36.992 -20.052 -57.183  1.00 60.74  ? 31  PHE C CD2   1 
ATOM   8377  C  CE1   . PHE C 1 31  ? -39.666 -20.495 -57.668  1.00 60.82  ? 31  PHE C CE1   1 
ATOM   8378  C  CE2   . PHE C 1 31  ? -37.952 -19.231 -56.612  1.00 59.67  ? 31  PHE C CE2   1 
ATOM   8379  C  CZ    . PHE C 1 31  ? -39.289 -19.448 -56.859  1.00 60.87  ? 31  PHE C CZ    1 
ATOM   8380  N  N     . THR C 1 32  ? -35.293 -25.339 -58.856  1.00 75.84  ? 32  THR C N     1 
ATOM   8381  C  CA    . THR C 1 32  ? -34.346 -26.263 -59.470  1.00 74.33  ? 32  THR C CA    1 
ATOM   8382  C  C     . THR C 1 32  ? -34.838 -26.602 -60.880  1.00 74.97  ? 32  THR C C     1 
ATOM   8383  O  O     . THR C 1 32  ? -35.905 -26.149 -61.287  1.00 69.91  ? 32  THR C O     1 
ATOM   8384  C  CB    . THR C 1 32  ? -34.160 -27.530 -58.622  1.00 72.97  ? 32  THR C CB    1 
ATOM   8385  O  OG1   . THR C 1 32  ? -35.428 -28.138 -58.392  1.00 69.84  ? 32  THR C OG1   1 
ATOM   8386  C  CG2   . THR C 1 32  ? -33.517 -27.266 -57.282  1.00 72.95  ? 32  THR C CG2   1 
ATOM   8387  N  N     . GLU C 1 33  ? -34.027 -27.358 -61.635  1.00 80.35  ? 33  GLU C N     1 
ATOM   8388  C  CA    . GLU C 1 33  ? -34.401 -27.930 -62.925  1.00 79.81  ? 33  GLU C CA    1 
ATOM   8389  C  C     . GLU C 1 33  ? -34.872 -26.836 -63.888  1.00 85.03  ? 33  GLU C C     1 
ATOM   8390  O  O     . GLU C 1 33  ? -34.143 -25.873 -64.103  1.00 87.68  ? 33  GLU C O     1 
ATOM   8391  C  CB    . GLU C 1 33  ? -35.381 -29.075 -62.679  1.00 79.39  ? 33  GLU C CB    1 
ATOM   8392  C  CG    . GLU C 1 33  ? -34.776 -30.128 -61.768  1.00 85.70  ? 33  GLU C CG    1 
ATOM   8393  C  CD    . GLU C 1 33  ? -35.690 -31.301 -61.486  1.00 89.71  ? 33  GLU C CD    1 
ATOM   8394  O  OE1   . GLU C 1 33  ? -35.201 -32.448 -61.480  1.00 83.47  ? 33  GLU C OE1   1 
ATOM   8395  O  OE2   . GLU C 1 33  ? -36.890 -31.057 -61.294  1.00 96.66  ? 33  GLU C OE2   1 
ATOM   8396  N  N     . ASP C 1 34  ? -36.063 -26.977 -64.494  1.00 82.87  ? 34  ASP C N     1 
ATOM   8397  C  CA    . ASP C 1 34  ? -36.441 -26.101 -65.599  1.00 92.03  ? 34  ASP C CA    1 
ATOM   8398  C  C     . ASP C 1 34  ? -37.106 -24.827 -65.077  1.00 89.76  ? 34  ASP C C     1 
ATOM   8399  O  O     . ASP C 1 34  ? -37.439 -23.946 -65.866  1.00 85.29  ? 34  ASP C O     1 
ATOM   8400  C  CB    . ASP C 1 34  ? -37.298 -26.833 -66.636  1.00 99.53  ? 34  ASP C CB    1 
ATOM   8401  C  CG    . ASP C 1 34  ? -38.723 -27.122 -66.201  1.00 102.34 ? 34  ASP C CG    1 
ATOM   8402  O  OD1   . ASP C 1 34  ? -38.945 -27.328 -64.984  1.00 98.86  ? 34  ASP C OD1   1 
ATOM   8403  O  OD2   . ASP C 1 34  ? -39.591 -27.180 -67.096  1.00 97.06  ? 34  ASP C OD2   1 
ATOM   8404  N  N     . LYS C 1 35  ? -37.259 -24.720 -63.747  1.00 89.40  ? 35  LYS C N     1 
ATOM   8405  C  CA    . LYS C 1 35  ? -37.595 -23.461 -63.095  1.00 92.18  ? 35  LYS C CA    1 
ATOM   8406  C  C     . LYS C 1 35  ? -36.377 -22.525 -63.047  1.00 87.71  ? 35  LYS C C     1 
ATOM   8407  O  O     . LYS C 1 35  ? -36.515 -21.359 -62.682  1.00 84.88  ? 35  LYS C O     1 
ATOM   8408  C  CB    . LYS C 1 35  ? -38.137 -23.727 -61.683  1.00 93.33  ? 35  LYS C CB    1 
ATOM   8409  C  CG    . LYS C 1 35  ? -39.534 -24.334 -61.604  1.00 91.07  ? 35  LYS C CG    1 
ATOM   8410  C  CD    . LYS C 1 35  ? -40.636 -23.303 -61.467  1.00 91.28  ? 35  LYS C CD    1 
ATOM   8411  C  CE    . LYS C 1 35  ? -42.027 -23.891 -61.571  1.00 94.41  ? 35  LYS C CE    1 
ATOM   8412  N  NZ    . LYS C 1 35  ? -42.333 -24.338 -62.953  1.00 94.84  ? 35  LYS C NZ    1 
ATOM   8413  N  N     . ILE C 1 36  ? -35.191 -23.009 -63.444  1.00 79.10  ? 36  ILE C N     1 
ATOM   8414  C  CA    . ILE C 1 36  ? -33.975 -22.212 -63.384  1.00 83.22  ? 36  ILE C CA    1 
ATOM   8415  C  C     . ILE C 1 36  ? -33.813 -21.331 -64.630  1.00 80.81  ? 36  ILE C C     1 
ATOM   8416  O  O     . ILE C 1 36  ? -32.890 -20.521 -64.674  1.00 70.46  ? 36  ILE C O     1 
ATOM   8417  C  CB    . ILE C 1 36  ? -32.740 -23.119 -63.174  1.00 87.78  ? 36  ILE C CB    1 
ATOM   8418  C  CG1   . ILE C 1 36  ? -31.650 -22.424 -62.355  1.00 85.72  ? 36  ILE C CG1   1 
ATOM   8419  C  CG2   . ILE C 1 36  ? -32.194 -23.644 -64.499  1.00 89.01  ? 36  ILE C CG2   1 
ATOM   8420  C  CD1   . ILE C 1 36  ? -32.066 -22.100 -60.946  1.00 89.09  ? 36  ILE C CD1   1 
ATOM   8421  N  N     . THR C 1 37  ? -34.682 -21.468 -65.643  1.00 77.38  ? 37  THR C N     1 
ATOM   8422  C  CA    . THR C 1 37  ? -34.406 -20.861 -66.938  1.00 80.29  ? 37  THR C CA    1 
ATOM   8423  C  C     . THR C 1 37  ? -34.346 -19.329 -66.835  1.00 78.70  ? 37  THR C C     1 
ATOM   8424  O  O     . THR C 1 37  ? -33.482 -18.735 -67.481  1.00 67.91  ? 37  THR C O     1 
ATOM   8425  C  CB    . THR C 1 37  ? -35.357 -21.375 -68.035  1.00 88.35  ? 37  THR C CB    1 
ATOM   8426  O  OG1   . THR C 1 37  ? -36.704 -21.290 -67.577  1.00 106.70 ? 37  THR C OG1   1 
ATOM   8427  C  CG2   . THR C 1 37  ? -35.088 -22.810 -68.439  1.00 91.42  ? 37  THR C CG2   1 
ATOM   8428  N  N     . PRO C 1 38  ? -35.178 -18.621 -66.018  1.00 72.09  ? 38  PRO C N     1 
ATOM   8429  C  CA    . PRO C 1 38  ? -35.141 -17.153 -65.959  1.00 70.74  ? 38  PRO C CA    1 
ATOM   8430  C  C     . PRO C 1 38  ? -33.860 -16.566 -65.363  1.00 68.03  ? 38  PRO C C     1 
ATOM   8431  O  O     . PRO C 1 38  ? -33.642 -15.354 -65.426  1.00 70.31  ? 38  PRO C O     1 
ATOM   8432  C  CB    . PRO C 1 38  ? -36.306 -16.752 -65.033  1.00 66.91  ? 38  PRO C CB    1 
ATOM   8433  C  CG    . PRO C 1 38  ? -37.160 -18.001 -64.922  1.00 70.42  ? 38  PRO C CG    1 
ATOM   8434  C  CD    . PRO C 1 38  ? -36.197 -19.161 -65.103  1.00 75.61  ? 38  PRO C CD    1 
ATOM   8435  N  N     . TYR C 1 39  ? -33.044 -17.442 -64.768  1.00 57.65  ? 39  TYR C N     1 
ATOM   8436  C  CA    . TYR C 1 39  ? -31.804 -17.079 -64.101  1.00 67.66  ? 39  TYR C CA    1 
ATOM   8437  C  C     . TYR C 1 39  ? -30.587 -17.274 -65.008  1.00 66.88  ? 39  TYR C C     1 
ATOM   8438  O  O     . TYR C 1 39  ? -29.468 -16.969 -64.602  1.00 59.00  ? 39  TYR C O     1 
ATOM   8439  C  CB    . TYR C 1 39  ? -31.650 -17.925 -62.838  1.00 64.01  ? 39  TYR C CB    1 
ATOM   8440  C  CG    . TYR C 1 39  ? -32.677 -17.642 -61.772  1.00 75.36  ? 39  TYR C CG    1 
ATOM   8441  C  CD1   . TYR C 1 39  ? -32.589 -16.499 -60.987  1.00 67.71  ? 39  TYR C CD1   1 
ATOM   8442  C  CD2   . TYR C 1 39  ? -33.743 -18.506 -61.548  1.00 70.11  ? 39  TYR C CD2   1 
ATOM   8443  C  CE1   . TYR C 1 39  ? -33.511 -16.241 -59.987  1.00 63.79  ? 39  TYR C CE1   1 
ATOM   8444  C  CE2   . TYR C 1 39  ? -34.679 -18.253 -60.557  1.00 69.87  ? 39  TYR C CE2   1 
ATOM   8445  C  CZ    . TYR C 1 39  ? -34.553 -17.123 -59.765  1.00 63.01  ? 39  TYR C CZ    1 
ATOM   8446  O  OH    . TYR C 1 39  ? -35.461 -16.870 -58.768  1.00 56.90  ? 39  TYR C OH    1 
ATOM   8447  N  N     . GLU C 1 40  ? -30.807 -17.826 -66.207  1.00 67.05  ? 40  GLU C N     1 
ATOM   8448  C  CA    . GLU C 1 40  ? -29.792 -17.878 -67.246  1.00 63.84  ? 40  GLU C CA    1 
ATOM   8449  C  C     . GLU C 1 40  ? -29.599 -16.465 -67.790  1.00 63.31  ? 40  GLU C C     1 
ATOM   8450  O  O     . GLU C 1 40  ? -30.563 -15.695 -67.861  1.00 60.84  ? 40  GLU C O     1 
ATOM   8451  C  CB    . GLU C 1 40  ? -30.231 -18.791 -68.399  1.00 63.22  ? 40  GLU C CB    1 
ATOM   8452  C  CG    . GLU C 1 40  ? -30.584 -20.207 -67.975  1.00 61.77  ? 40  GLU C CG    1 
ATOM   8453  C  CD    . GLU C 1 40  ? -29.412 -21.098 -67.609  1.00 60.28  ? 40  GLU C CD    1 
ATOM   8454  O  OE1   . GLU C 1 40  ? -28.261 -20.741 -67.943  1.00 67.04  ? 40  GLU C OE1   1 
ATOM   8455  O  OE2   . GLU C 1 40  ? -29.654 -22.154 -66.987  1.00 65.12  ? 40  GLU C OE2   1 
ATOM   8456  N  N     . ASP C 1 41  ? -28.361 -16.151 -68.192  1.00 60.25  ? 41  ASP C N     1 
ATOM   8457  C  CA    . ASP C 1 41  ? -28.080 -14.927 -68.925  1.00 68.60  ? 41  ASP C CA    1 
ATOM   8458  C  C     . ASP C 1 41  ? -29.001 -14.906 -70.144  1.00 70.39  ? 41  ASP C C     1 
ATOM   8459  O  O     . ASP C 1 41  ? -28.957 -15.833 -70.951  1.00 70.17  ? 41  ASP C O     1 
ATOM   8460  C  CB    . ASP C 1 41  ? -26.594 -14.846 -69.309  1.00 65.67  ? 41  ASP C CB    1 
ATOM   8461  C  CG    . ASP C 1 41  ? -26.163 -13.597 -70.070  1.00 65.97  ? 41  ASP C CG    1 
ATOM   8462  O  OD1   . ASP C 1 41  ? -26.936 -12.617 -70.135  1.00 71.89  ? 41  ASP C OD1   1 
ATOM   8463  O  OD2   . ASP C 1 41  ? -25.040 -13.617 -70.603  1.00 69.35  ? 41  ASP C OD2   1 
ATOM   8464  N  N     . PRO C 1 42  ? -29.873 -13.880 -70.312  1.00 67.21  ? 42  PRO C N     1 
ATOM   8465  C  CA    . PRO C 1 42  ? -30.723 -13.797 -71.501  1.00 64.22  ? 42  PRO C CA    1 
ATOM   8466  C  C     . PRO C 1 42  ? -29.910 -13.608 -72.788  1.00 65.67  ? 42  PRO C C     1 
ATOM   8467  O  O     . PRO C 1 42  ? -30.334 -14.051 -73.852  1.00 59.13  ? 42  PRO C O     1 
ATOM   8468  C  CB    . PRO C 1 42  ? -31.647 -12.591 -71.233  1.00 64.82  ? 42  PRO C CB    1 
ATOM   8469  C  CG    . PRO C 1 42  ? -30.932 -11.765 -70.175  1.00 64.88  ? 42  PRO C CG    1 
ATOM   8470  C  CD    . PRO C 1 42  ? -30.064 -12.739 -69.401  1.00 67.77  ? 42  PRO C CD    1 
ATOM   8471  N  N     . TYR C 1 43  ? -28.739 -12.960 -72.678  1.00 63.14  ? 43  TYR C N     1 
ATOM   8472  C  CA    . TYR C 1 43  ? -27.897 -12.638 -73.823  1.00 65.75  ? 43  TYR C CA    1 
ATOM   8473  C  C     . TYR C 1 43  ? -26.656 -13.523 -73.816  1.00 65.84  ? 43  TYR C C     1 
ATOM   8474  O  O     . TYR C 1 43  ? -25.586 -13.084 -73.390  1.00 73.14  ? 43  TYR C O     1 
ATOM   8475  C  CB    . TYR C 1 43  ? -27.497 -11.162 -73.758  1.00 66.01  ? 43  TYR C CB    1 
ATOM   8476  C  CG    . TYR C 1 43  ? -28.643 -10.192 -73.620  1.00 63.40  ? 43  TYR C CG    1 
ATOM   8477  C  CD1   . TYR C 1 43  ? -29.918 -10.474 -74.104  1.00 63.87  ? 43  TYR C CD1   1 
ATOM   8478  C  CD2   . TYR C 1 43  ? -28.453 -8.987  -72.967  1.00 64.17  ? 43  TYR C CD2   1 
ATOM   8479  C  CE1   . TYR C 1 43  ? -30.961 -9.566  -73.981  1.00 62.54  ? 43  TYR C CE1   1 
ATOM   8480  C  CE2   . TYR C 1 43  ? -29.481 -8.069  -72.845  1.00 64.05  ? 43  TYR C CE2   1 
ATOM   8481  C  CZ    . TYR C 1 43  ? -30.735 -8.356  -73.344  1.00 68.67  ? 43  TYR C CZ    1 
ATOM   8482  O  OH    . TYR C 1 43  ? -31.677 -7.386  -73.161  1.00 64.22  ? 43  TYR C OH    1 
ATOM   8483  N  N     . THR C 1 44  ? -26.823 -14.769 -74.282  1.00 66.08  ? 44  THR C N     1 
ATOM   8484  C  CA    . THR C 1 44  ? -25.765 -15.777 -74.317  1.00 62.16  ? 44  THR C CA    1 
ATOM   8485  C  C     . THR C 1 44  ? -24.568 -15.288 -75.139  1.00 65.18  ? 44  THR C C     1 
ATOM   8486  O  O     . THR C 1 44  ? -24.741 -14.526 -76.095  1.00 67.21  ? 44  THR C O     1 
ATOM   8487  C  CB    . THR C 1 44  ? -26.320 -17.096 -74.875  1.00 62.81  ? 44  THR C CB    1 
ATOM   8488  O  OG1   . THR C 1 44  ? -27.560 -17.329 -74.202  1.00 57.28  ? 44  THR C OG1   1 
ATOM   8489  C  CG2   . THR C 1 44  ? -25.381 -18.275 -74.703  1.00 62.49  ? 44  THR C CG2   1 
ATOM   8490  N  N     . ILE C 1 45  ? -23.358 -15.720 -74.730  1.00 66.58  ? 45  ILE C N     1 
ATOM   8491  C  CA    . ILE C 1 45  ? -22.095 -15.414 -75.401  1.00 68.47  ? 45  ILE C CA    1 
ATOM   8492  C  C     . ILE C 1 45  ? -21.305 -16.704 -75.672  1.00 66.59  ? 45  ILE C C     1 
ATOM   8493  O  O     . ILE C 1 45  ? -20.763 -16.890 -76.762  1.00 62.82  ? 45  ILE C O     1 
ATOM   8494  C  CB    . ILE C 1 45  ? -21.241 -14.432 -74.572  1.00 61.49  ? 45  ILE C CB    1 
ATOM   8495  C  CG1   . ILE C 1 45  ? -21.884 -13.045 -74.436  1.00 68.72  ? 45  ILE C CG1   1 
ATOM   8496  C  CG2   . ILE C 1 45  ? -19.845 -14.357 -75.165  1.00 55.91  ? 45  ILE C CG2   1 
ATOM   8497  C  CD1   . ILE C 1 45  ? -21.127 -12.073 -73.521  1.00 62.19  ? 45  ILE C CD1   1 
ATOM   8498  N  N     . SER C 1 46  ? -21.177 -17.538 -74.633  1.00 67.31  ? 46  SER C N     1 
ATOM   8499  C  CA    . SER C 1 46  ? -20.525 -18.840 -74.688  1.00 76.45  ? 46  SER C CA    1 
ATOM   8500  C  C     . SER C 1 46  ? -21.313 -19.811 -75.572  1.00 79.77  ? 46  SER C C     1 
ATOM   8501  O  O     . SER C 1 46  ? -22.542 -19.742 -75.642  1.00 73.33  ? 46  SER C O     1 
ATOM   8502  C  CB    . SER C 1 46  ? -20.364 -19.382 -73.281  1.00 76.03  ? 46  SER C CB    1 
ATOM   8503  O  OG    . SER C 1 46  ? -19.579 -20.563 -73.251  1.00 69.37  ? 46  SER C OG    1 
ATOM   8504  N  N     . ASN C 1 47  ? -20.571 -20.689 -76.266  1.00 86.66  ? 47  ASN C N     1 
ATOM   8505  C  CA    . ASN C 1 47  ? -21.120 -21.815 -77.014  1.00 88.36  ? 47  ASN C CA    1 
ATOM   8506  C  C     . ASN C 1 47  ? -20.953 -23.103 -76.206  1.00 84.01  ? 47  ASN C C     1 
ATOM   8507  O  O     . ASN C 1 47  ? -21.489 -24.152 -76.575  1.00 80.47  ? 47  ASN C O     1 
ATOM   8508  C  CB    . ASN C 1 47  ? -20.464 -21.940 -78.394  1.00 81.38  ? 47  ASN C CB    1 
ATOM   8509  C  CG    . ASN C 1 47  ? -20.694 -20.716 -79.253  1.00 73.00  ? 47  ASN C CG    1 
ATOM   8510  O  OD1   . ASN C 1 47  ? -21.822 -20.243 -79.352  1.00 63.27  ? 47  ASN C OD1   1 
ATOM   8511  N  ND2   . ASN C 1 47  ? -19.638 -20.183 -79.848  1.00 66.47  ? 47  ASN C ND2   1 
ATOM   8512  N  N     . ASP C 1 48  ? -20.191 -22.996 -75.105  1.00 84.53  ? 48  ASP C N     1 
ATOM   8513  C  CA    . ASP C 1 48  ? -20.042 -24.044 -74.105  1.00 79.34  ? 48  ASP C CA    1 
ATOM   8514  C  C     . ASP C 1 48  ? -21.149 -23.897 -73.054  1.00 79.06  ? 48  ASP C C     1 
ATOM   8515  O  O     . ASP C 1 48  ? -21.073 -23.017 -72.189  1.00 66.92  ? 48  ASP C O     1 
ATOM   8516  C  CB    . ASP C 1 48  ? -18.642 -23.971 -73.490  1.00 71.85  ? 48  ASP C CB    1 
ATOM   8517  C  CG    . ASP C 1 48  ? -18.356 -25.026 -72.433  1.00 79.48  ? 48  ASP C CG    1 
ATOM   8518  O  OD1   . ASP C 1 48  ? -19.240 -25.868 -72.181  1.00 76.27  ? 48  ASP C OD1   1 
ATOM   8519  O  OD2   . ASP C 1 48  ? -17.248 -24.989 -71.861  1.00 85.40  ? 48  ASP C OD2   1 
ATOM   8520  N  N     . GLU C 1 49  ? -22.144 -24.798 -73.115  1.00 77.94  ? 49  GLU C N     1 
ATOM   8521  C  CA    . GLU C 1 49  ? -23.368 -24.700 -72.331  1.00 74.52  ? 49  GLU C CA    1 
ATOM   8522  C  C     . GLU C 1 49  ? -23.177 -25.212 -70.897  1.00 75.74  ? 49  GLU C C     1 
ATOM   8523  O  O     . GLU C 1 49  ? -24.154 -25.311 -70.154  1.00 72.88  ? 49  GLU C O     1 
ATOM   8524  C  CB    . GLU C 1 49  ? -24.475 -25.501 -73.018  1.00 78.93  ? 49  GLU C CB    1 
ATOM   8525  C  CG    . GLU C 1 49  ? -24.830 -25.015 -74.413  1.00 84.24  ? 49  GLU C CG    1 
ATOM   8526  C  CD    . GLU C 1 49  ? -25.222 -26.133 -75.368  1.00 90.16  ? 49  GLU C CD    1 
ATOM   8527  O  OE1   . GLU C 1 49  ? -26.224 -26.835 -75.092  1.00 80.85  ? 49  GLU C OE1   1 
ATOM   8528  O  OE2   . GLU C 1 49  ? -24.505 -26.319 -76.375  1.00 89.74  ? 49  GLU C OE2   1 
ATOM   8529  N  N     . THR C 1 50  ? -21.931 -25.536 -70.505  1.00 69.33  ? 50  THR C N     1 
ATOM   8530  C  CA    . THR C 1 50  ? -21.602 -25.888 -69.129  1.00 79.84  ? 50  THR C CA    1 
ATOM   8531  C  C     . THR C 1 50  ? -21.000 -24.706 -68.357  1.00 80.19  ? 50  THR C C     1 
ATOM   8532  O  O     . THR C 1 50  ? -20.484 -24.903 -67.253  1.00 71.77  ? 50  THR C O     1 
ATOM   8533  C  CB    . THR C 1 50  ? -20.569 -27.020 -69.086  1.00 85.24  ? 50  THR C CB    1 
ATOM   8534  O  OG1   . THR C 1 50  ? -19.389 -26.479 -69.686  1.00 82.40  ? 50  THR C OG1   1 
ATOM   8535  C  CG2   . THR C 1 50  ? -21.021 -28.282 -69.792  1.00 88.13  ? 50  THR C CG2   1 
ATOM   8536  N  N     . GLU C 1 51  ? -21.045 -23.496 -68.942  1.00 75.12  ? 51  GLU C N     1 
ATOM   8537  C  CA    . GLU C 1 51  ? -20.448 -22.306 -68.347  1.00 78.89  ? 51  GLU C CA    1 
ATOM   8538  C  C     . GLU C 1 51  ? -21.531 -21.321 -67.911  1.00 74.93  ? 51  GLU C C     1 
ATOM   8539  O  O     . GLU C 1 51  ? -22.502 -21.134 -68.639  1.00 66.44  ? 51  GLU C O     1 
ATOM   8540  C  CB    . GLU C 1 51  ? -19.517 -21.608 -69.340  1.00 81.57  ? 51  GLU C CB    1 
ATOM   8541  C  CG    . GLU C 1 51  ? -18.206 -22.341 -69.557  1.00 81.24  ? 51  GLU C CG    1 
ATOM   8542  C  CD    . GLU C 1 51  ? -17.244 -21.601 -70.468  1.00 76.59  ? 51  GLU C CD    1 
ATOM   8543  O  OE1   . GLU C 1 51  ? -17.681 -21.155 -71.546  1.00 80.71  ? 51  GLU C OE1   1 
ATOM   8544  O  OE2   . GLU C 1 51  ? -16.060 -21.484 -70.102  1.00 80.87  ? 51  GLU C OE2   1 
ATOM   8545  N  N     . HIS C 1 52  ? -21.335 -20.692 -66.732  1.00 69.85  ? 52  HIS C N     1 
ATOM   8546  C  CA    . HIS C 1 52  ? -22.225 -19.659 -66.209  1.00 59.38  ? 52  HIS C CA    1 
ATOM   8547  C  C     . HIS C 1 52  ? -23.643 -20.200 -66.002  1.00 63.30  ? 52  HIS C C     1 
ATOM   8548  O  O     . HIS C 1 52  ? -24.617 -19.505 -66.303  1.00 57.62  ? 52  HIS C O     1 
ATOM   8549  C  CB    . HIS C 1 52  ? -22.235 -18.426 -67.124  1.00 55.52  ? 52  HIS C CB    1 
ATOM   8550  C  CG    . HIS C 1 52  ? -20.883 -18.060 -67.639  1.00 64.46  ? 52  HIS C CG    1 
ATOM   8551  N  ND1   . HIS C 1 52  ? -19.769 -17.999 -66.825  1.00 70.00  ? 52  HIS C ND1   1 
ATOM   8552  C  CD2   . HIS C 1 52  ? -20.459 -17.770 -68.878  1.00 61.27  ? 52  HIS C CD2   1 
ATOM   8553  C  CE1   . HIS C 1 52  ? -18.719 -17.651 -67.557  1.00 74.68  ? 52  HIS C CE1   1 
ATOM   8554  N  NE2   . HIS C 1 52  ? -19.113 -17.507 -68.808  1.00 70.46  ? 52  HIS C NE2   1 
ATOM   8555  N  N     . ARG C 1 53  ? -23.735 -21.439 -65.479  1.00 71.18  ? 53  ARG C N     1 
ATOM   8556  C  CA    . ARG C 1 53  ? -24.989 -22.170 -65.329  1.00 74.27  ? 53  ARG C CA    1 
ATOM   8557  C  C     . ARG C 1 53  ? -25.368 -22.244 -63.849  1.00 69.00  ? 53  ARG C C     1 
ATOM   8558  O  O     . ARG C 1 53  ? -24.691 -22.916 -63.073  1.00 76.72  ? 53  ARG C O     1 
ATOM   8559  C  CB    . ARG C 1 53  ? -24.868 -23.607 -65.856  1.00 70.88  ? 53  ARG C CB    1 
ATOM   8560  C  CG    . ARG C 1 53  ? -24.212 -23.735 -67.224  1.00 78.90  ? 53  ARG C CG    1 
ATOM   8561  C  CD    . ARG C 1 53  ? -24.931 -22.936 -68.297  1.00 82.28  ? 53  ARG C CD    1 
ATOM   8562  N  NE    . ARG C 1 53  ? -26.369 -23.167 -68.315  1.00 82.97  ? 53  ARG C NE    1 
ATOM   8563  C  CZ    . ARG C 1 53  ? -26.947 -24.342 -68.527  1.00 81.75  ? 53  ARG C CZ    1 
ATOM   8564  N  NH1   . ARG C 1 53  ? -26.213 -25.419 -68.747  1.00 81.88  ? 53  ARG C NH1   1 
ATOM   8565  N  NH2   . ARG C 1 53  ? -28.265 -24.433 -68.511  1.00 76.91  ? 53  ARG C NH2   1 
ATOM   8566  N  N     . PRO C 1 54  ? -26.453 -21.569 -63.404  1.00 56.60  ? 54  PRO C N     1 
ATOM   8567  C  CA    . PRO C 1 54  ? -26.912 -21.696 -62.021  1.00 60.04  ? 54  PRO C CA    1 
ATOM   8568  C  C     . PRO C 1 54  ? -27.527 -23.081 -61.825  1.00 50.05  ? 54  PRO C C     1 
ATOM   8569  O  O     . PRO C 1 54  ? -28.245 -23.557 -62.695  1.00 52.94  ? 54  PRO C O     1 
ATOM   8570  C  CB    . PRO C 1 54  ? -27.935 -20.559 -61.856  1.00 51.87  ? 54  PRO C CB    1 
ATOM   8571  C  CG    . PRO C 1 54  ? -28.443 -20.313 -63.256  1.00 55.82  ? 54  PRO C CG    1 
ATOM   8572  C  CD    . PRO C 1 54  ? -27.311 -20.679 -64.194  1.00 54.96  ? 54  PRO C CD    1 
ATOM   8573  N  N     . TYR C 1 55  ? -27.211 -23.712 -60.694  1.00 50.43  ? 55  TYR C N     1 
ATOM   8574  C  CA    . TYR C 1 55  ? -27.744 -25.011 -60.341  1.00 57.10  ? 55  TYR C CA    1 
ATOM   8575  C  C     . TYR C 1 55  ? -29.158 -24.875 -59.783  1.00 64.54  ? 55  TYR C C     1 
ATOM   8576  O  O     . TYR C 1 55  ? -29.998 -25.738 -60.021  1.00 61.86  ? 55  TYR C O     1 
ATOM   8577  C  CB    . TYR C 1 55  ? -26.828 -25.677 -59.316  1.00 63.32  ? 55  TYR C CB    1 
ATOM   8578  C  CG    . TYR C 1 55  ? -27.175 -27.108 -59.011  1.00 73.05  ? 55  TYR C CG    1 
ATOM   8579  C  CD1   . TYR C 1 55  ? -28.130 -27.431 -58.059  1.00 73.95  ? 55  TYR C CD1   1 
ATOM   8580  C  CD2   . TYR C 1 55  ? -26.566 -28.144 -59.702  1.00 78.93  ? 55  TYR C CD2   1 
ATOM   8581  C  CE1   . TYR C 1 55  ? -28.456 -28.750 -57.785  1.00 69.81  ? 55  TYR C CE1   1 
ATOM   8582  C  CE2   . TYR C 1 55  ? -26.891 -29.467 -59.449  1.00 79.18  ? 55  TYR C CE2   1 
ATOM   8583  C  CZ    . TYR C 1 55  ? -27.848 -29.771 -58.497  1.00 76.55  ? 55  TYR C CZ    1 
ATOM   8584  O  OH    . TYR C 1 55  ? -28.152 -31.088 -58.244  1.00 76.61  ? 55  TYR C OH    1 
ATOM   8585  N  N     . ALA C 1 56  ? -29.388 -23.830 -58.977  1.00 68.13  ? 56  ALA C N     1 
ATOM   8586  C  CA    . ALA C 1 56  ? -30.675 -23.611 -58.324  1.00 62.10  ? 56  ALA C CA    1 
ATOM   8587  C  C     . ALA C 1 56  ? -30.785 -22.148 -57.891  1.00 65.42  ? 56  ALA C C     1 
ATOM   8588  O  O     . ALA C 1 56  ? -29.799 -21.410 -57.961  1.00 62.11  ? 56  ALA C O     1 
ATOM   8589  C  CB    . ALA C 1 56  ? -30.812 -24.537 -57.150  1.00 54.39  ? 56  ALA C CB    1 
ATOM   8590  N  N     . ALA C 1 57  ? -31.990 -21.741 -57.469  1.00 60.54  ? 57  ALA C N     1 
ATOM   8591  C  CA    . ALA C 1 57  ? -32.209 -20.422 -56.886  1.00 61.70  ? 57  ALA C CA    1 
ATOM   8592  C  C     . ALA C 1 57  ? -32.994 -20.549 -55.581  1.00 63.07  ? 57  ALA C C     1 
ATOM   8593  O  O     . ALA C 1 57  ? -33.775 -21.483 -55.414  1.00 56.23  ? 57  ALA C O     1 
ATOM   8594  C  CB    . ALA C 1 57  ? -32.923 -19.519 -57.856  1.00 57.15  ? 57  ALA C CB    1 
ATOM   8595  N  N     . VAL C 1 58  ? -32.764 -19.596 -54.669  1.00 54.47  ? 58  VAL C N     1 
ATOM   8596  C  CA    . VAL C 1 58  ? -33.509 -19.480 -53.425  1.00 51.47  ? 58  VAL C CA    1 
ATOM   8597  C  C     . VAL C 1 58  ? -33.936 -18.015 -53.305  1.00 54.00  ? 58  VAL C C     1 
ATOM   8598  O  O     . VAL C 1 58  ? -33.131 -17.132 -53.594  1.00 51.21  ? 58  VAL C O     1 
ATOM   8599  C  CB    . VAL C 1 58  ? -32.662 -20.010 -52.247  1.00 50.30  ? 58  VAL C CB    1 
ATOM   8600  C  CG1   . VAL C 1 58  ? -31.363 -19.254 -52.083  1.00 57.43  ? 58  VAL C CG1   1 
ATOM   8601  C  CG2   . VAL C 1 58  ? -33.404 -20.011 -50.916  1.00 50.71  ? 58  VAL C CG2   1 
ATOM   8602  N  N     . ALA C 1 59  ? -35.220 -17.754 -52.995  1.00 50.67  ? 59  ALA C N     1 
ATOM   8603  C  CA    . ALA C 1 59  ? -35.736 -16.395 -52.932  1.00 44.91  ? 59  ALA C CA    1 
ATOM   8604  C  C     . ALA C 1 59  ? -36.239 -16.072 -51.517  1.00 53.74  ? 59  ALA C C     1 
ATOM   8605  O  O     . ALA C 1 59  ? -37.412 -16.299 -51.186  1.00 52.34  ? 59  ALA C O     1 
ATOM   8606  C  CB    . ALA C 1 59  ? -36.827 -16.205 -53.951  1.00 45.57  ? 59  ALA C CB    1 
ATOM   8607  N  N     . PRO C 1 60  ? -35.382 -15.513 -50.631  1.00 48.53  ? 60  PRO C N     1 
ATOM   8608  C  CA    . PRO C 1 60  ? -35.766 -15.254 -49.236  1.00 48.48  ? 60  PRO C CA    1 
ATOM   8609  C  C     . PRO C 1 60  ? -36.711 -14.070 -49.100  1.00 43.53  ? 60  PRO C C     1 
ATOM   8610  O  O     . PRO C 1 60  ? -36.845 -13.284 -50.031  1.00 48.59  ? 60  PRO C O     1 
ATOM   8611  C  CB    . PRO C 1 60  ? -34.427 -15.006 -48.532  1.00 49.36  ? 60  PRO C CB    1 
ATOM   8612  C  CG    . PRO C 1 60  ? -33.527 -14.446 -49.637  1.00 48.37  ? 60  PRO C CG    1 
ATOM   8613  C  CD    . PRO C 1 60  ? -33.987 -15.132 -50.910  1.00 54.03  ? 60  PRO C CD    1 
ATOM   8614  N  N     . ALA C 1 61  ? -37.390 -13.977 -47.946  1.00 50.98  ? 61  ALA C N     1 
ATOM   8615  C  CA    . ALA C 1 61  ? -38.394 -12.949 -47.709  1.00 54.64  ? 61  ALA C CA    1 
ATOM   8616  C  C     . ALA C 1 61  ? -37.835 -11.830 -46.834  1.00 49.60  ? 61  ALA C C     1 
ATOM   8617  O  O     . ALA C 1 61  ? -38.510 -10.831 -46.624  1.00 48.04  ? 61  ALA C O     1 
ATOM   8618  C  CB    . ALA C 1 61  ? -39.631 -13.547 -47.071  1.00 51.18  ? 61  ALA C CB    1 
ATOM   8619  N  N     . SER C 1 62  ? -36.626 -11.998 -46.306  1.00 46.84  ? 62  SER C N     1 
ATOM   8620  C  CA    . SER C 1 62  ? -36.164 -11.104 -45.265  1.00 44.84  ? 62  SER C CA    1 
ATOM   8621  C  C     . SER C 1 62  ? -34.660 -11.270 -45.072  1.00 44.14  ? 62  SER C C     1 
ATOM   8622  O  O     . SER C 1 62  ? -34.100 -12.278 -45.491  1.00 46.20  ? 62  SER C O     1 
ATOM   8623  C  CB    . SER C 1 62  ? -36.929 -11.371 -43.961  1.00 48.41  ? 62  SER C CB    1 
ATOM   8624  O  OG    . SER C 1 62  ? -36.464 -12.548 -43.296  1.00 40.44  ? 62  SER C OG    1 
ATOM   8625  N  N     . THR C 1 63  ? -34.051 -10.294 -44.376  1.00 42.06  ? 63  THR C N     1 
ATOM   8626  C  CA    . THR C 1 63  ? -32.630 -10.291 -44.043  1.00 41.65  ? 63  THR C CA    1 
ATOM   8627  C  C     . THR C 1 63  ? -32.276 -11.543 -43.249  1.00 42.45  ? 63  THR C C     1 
ATOM   8628  O  O     . THR C 1 63  ? -31.258 -12.191 -43.487  1.00 40.30  ? 63  THR C O     1 
ATOM   8629  C  CB    . THR C 1 63  ? -32.263 -9.027  -43.249  1.00 37.90  ? 63  THR C CB    1 
ATOM   8630  O  OG1   . THR C 1 63  ? -32.445 -7.945  -44.152  1.00 35.72  ? 63  THR C OG1   1 
ATOM   8631  C  CG2   . THR C 1 63  ? -30.856 -9.023  -42.691  1.00 40.90  ? 63  THR C CG2   1 
ATOM   8632  N  N     . GLU C 1 64  ? -33.129 -11.888 -42.288  1.00 43.12  ? 64  GLU C N     1 
ATOM   8633  C  CA    . GLU C 1 64  ? -32.793 -12.959 -41.364  1.00 41.01  ? 64  GLU C CA    1 
ATOM   8634  C  C     . GLU C 1 64  ? -32.806 -14.305 -42.093  1.00 37.06  ? 64  GLU C C     1 
ATOM   8635  O  O     . GLU C 1 64  ? -32.046 -15.193 -41.737  1.00 40.25  ? 64  GLU C O     1 
ATOM   8636  C  CB    . GLU C 1 64  ? -33.741 -12.939 -40.161  1.00 43.86  ? 64  GLU C CB    1 
ATOM   8637  C  CG    . GLU C 1 64  ? -33.167 -13.644 -38.938  1.00 48.08  ? 64  GLU C CG    1 
ATOM   8638  C  CD    . GLU C 1 64  ? -33.204 -15.161 -39.011  1.00 46.83  ? 64  GLU C CD    1 
ATOM   8639  O  OE1   . GLU C 1 64  ? -34.169 -15.683 -39.632  1.00 45.16  ? 64  GLU C OE1   1 
ATOM   8640  O  OE2   . GLU C 1 64  ? -32.295 -15.808 -38.445  1.00 42.00  ? 64  GLU C OE2   1 
ATOM   8641  N  N     . GLU C 1 65  ? -33.677 -14.473 -43.090  1.00 39.86  ? 65  GLU C N     1 
ATOM   8642  C  CA    . GLU C 1 65  ? -33.642 -15.683 -43.902  1.00 45.88  ? 65  GLU C CA    1 
ATOM   8643  C  C     . GLU C 1 65  ? -32.336 -15.717 -44.688  1.00 49.46  ? 65  GLU C C     1 
ATOM   8644  O  O     . GLU C 1 65  ? -31.689 -16.771 -44.752  1.00 42.70  ? 65  GLU C O     1 
ATOM   8645  C  CB    . GLU C 1 65  ? -34.852 -15.742 -44.825  1.00 46.49  ? 65  GLU C CB    1 
ATOM   8646  C  CG    . GLU C 1 65  ? -36.103 -16.051 -44.032  1.00 48.85  ? 65  GLU C CG    1 
ATOM   8647  C  CD    . GLU C 1 65  ? -37.401 -16.049 -44.810  1.00 52.64  ? 65  GLU C CD    1 
ATOM   8648  O  OE1   . GLU C 1 65  ? -37.358 -16.092 -46.058  1.00 54.03  ? 65  GLU C OE1   1 
ATOM   8649  O  OE2   . GLU C 1 65  ? -38.450 -15.957 -44.156  1.00 53.74  ? 65  GLU C OE2   1 
ATOM   8650  N  N     . VAL C 1 66  ? -31.941 -14.546 -45.227  1.00 42.23  ? 66  VAL C N     1 
ATOM   8651  C  CA    . VAL C 1 66  ? -30.665 -14.442 -45.909  1.00 39.27  ? 66  VAL C CA    1 
ATOM   8652  C  C     . VAL C 1 66  ? -29.596 -15.026 -44.999  1.00 37.93  ? 66  VAL C C     1 
ATOM   8653  O  O     . VAL C 1 66  ? -28.811 -15.860 -45.439  1.00 40.95  ? 66  VAL C O     1 
ATOM   8654  C  CB    . VAL C 1 66  ? -30.290 -13.008 -46.345  1.00 41.83  ? 66  VAL C CB    1 
ATOM   8655  C  CG1   . VAL C 1 66  ? -28.832 -12.945 -46.766  1.00 44.92  ? 66  VAL C CG1   1 
ATOM   8656  C  CG2   . VAL C 1 66  ? -31.167 -12.470 -47.459  1.00 42.51  ? 66  VAL C CG2   1 
ATOM   8657  N  N     . GLN C 1 67  ? -29.536 -14.563 -43.746  1.00 42.69  ? 67  GLN C N     1 
ATOM   8658  C  CA    . GLN C 1 67  ? -28.491 -14.982 -42.813  1.00 40.48  ? 67  GLN C CA    1 
ATOM   8659  C  C     . GLN C 1 67  ? -28.523 -16.497 -42.610  1.00 42.80  ? 67  GLN C C     1 
ATOM   8660  O  O     . GLN C 1 67  ? -27.490 -17.129 -42.495  1.00 38.39  ? 67  GLN C O     1 
ATOM   8661  C  CB    . GLN C 1 67  ? -28.675 -14.349 -41.428  1.00 41.84  ? 67  GLN C CB    1 
ATOM   8662  C  CG    . GLN C 1 67  ? -28.443 -12.839 -41.399  1.00 42.66  ? 67  GLN C CG    1 
ATOM   8663  C  CD    . GLN C 1 67  ? -28.817 -12.221 -40.075  1.00 42.29  ? 67  GLN C CD    1 
ATOM   8664  O  OE1   . GLN C 1 67  ? -29.926 -11.719 -39.896  1.00 37.25  ? 67  GLN C OE1   1 
ATOM   8665  N  NE2   . GLN C 1 67  ? -27.891 -12.272 -39.135  1.00 39.65  ? 67  GLN C NE2   1 
ATOM   8666  N  N     . GLU C 1 68  ? -29.723 -17.070 -42.512  1.00 44.50  ? 68  GLU C N     1 
ATOM   8667  C  CA    . GLU C 1 68  ? -29.848 -18.498 -42.286  1.00 46.68  ? 68  GLU C CA    1 
ATOM   8668  C  C     . GLU C 1 68  ? -29.331 -19.246 -43.517  1.00 48.20  ? 68  GLU C C     1 
ATOM   8669  O  O     . GLU C 1 68  ? -28.627 -20.245 -43.363  1.00 46.88  ? 68  GLU C O     1 
ATOM   8670  C  CB    . GLU C 1 68  ? -31.296 -18.848 -41.962  1.00 45.06  ? 68  GLU C CB    1 
ATOM   8671  C  CG    . GLU C 1 68  ? -31.787 -18.299 -40.636  1.00 51.20  ? 68  GLU C CG    1 
ATOM   8672  C  CD    . GLU C 1 68  ? -33.077 -18.948 -40.154  1.00 50.17  ? 68  GLU C CD    1 
ATOM   8673  O  OE1   . GLU C 1 68  ? -33.067 -20.169 -39.940  1.00 53.10  ? 68  GLU C OE1   1 
ATOM   8674  O  OE2   . GLU C 1 68  ? -34.076 -18.250 -40.021  1.00 50.98  ? 68  GLU C OE2   1 
ATOM   8675  N  N     . ILE C 1 69  ? -29.642 -18.711 -44.715  1.00 43.67  ? 69  ILE C N     1 
ATOM   8676  C  CA    . ILE C 1 69  ? -29.220 -19.300 -45.981  1.00 43.30  ? 69  ILE C CA    1 
ATOM   8677  C  C     . ILE C 1 69  ? -27.696 -19.326 -46.024  1.00 44.65  ? 69  ILE C C     1 
ATOM   8678  O  O     . ILE C 1 69  ? -27.117 -20.359 -46.296  1.00 43.54  ? 69  ILE C O     1 
ATOM   8679  C  CB    . ILE C 1 69  ? -29.847 -18.576 -47.195  1.00 44.24  ? 69  ILE C CB    1 
ATOM   8680  C  CG1   . ILE C 1 69  ? -31.338 -18.897 -47.306  1.00 39.25  ? 69  ILE C CG1   1 
ATOM   8681  C  CG2   . ILE C 1 69  ? -29.114 -18.926 -48.484  1.00 46.00  ? 69  ILE C CG2   1 
ATOM   8682  C  CD1   . ILE C 1 69  ? -32.143 -17.908 -48.057  1.00 38.50  ? 69  ILE C CD1   1 
ATOM   8683  N  N     . VAL C 1 70  ? -27.052 -18.225 -45.644  1.00 39.66  ? 70  VAL C N     1 
ATOM   8684  C  CA    . VAL C 1 70  ? -25.607 -18.145 -45.645  1.00 40.98  ? 70  VAL C CA    1 
ATOM   8685  C  C     . VAL C 1 70  ? -24.980 -19.113 -44.657  1.00 39.34  ? 70  VAL C C     1 
ATOM   8686  O  O     . VAL C 1 70  ? -23.879 -19.585 -44.910  1.00 45.15  ? 70  VAL C O     1 
ATOM   8687  C  CB    . VAL C 1 70  ? -25.166 -16.694 -45.358  1.00 43.33  ? 70  VAL C CB    1 
ATOM   8688  C  CG1   . VAL C 1 70  ? -23.683 -16.598 -45.031  1.00 41.48  ? 70  VAL C CG1   1 
ATOM   8689  C  CG2   . VAL C 1 70  ? -25.535 -15.783 -46.511  1.00 39.84  ? 70  VAL C CG2   1 
ATOM   8690  N  N     . ARG C 1 71  ? -25.599 -19.318 -43.485  1.00 46.38  ? 71  ARG C N     1 
ATOM   8691  C  CA    . ARG C 1 71  ? -25.086 -20.274 -42.504  1.00 46.20  ? 71  ARG C CA    1 
ATOM   8692  C  C     . ARG C 1 71  ? -25.091 -21.696 -43.081  1.00 44.72  ? 71  ARG C C     1 
ATOM   8693  O  O     . ARG C 1 71  ? -24.097 -22.406 -42.989  1.00 48.36  ? 71  ARG C O     1 
ATOM   8694  C  CB    . ARG C 1 71  ? -25.872 -20.198 -41.192  1.00 46.29  ? 71  ARG C CB    1 
ATOM   8695  C  CG    . ARG C 1 71  ? -25.758 -18.839 -40.519  1.00 49.41  ? 71  ARG C CG    1 
ATOM   8696  C  CD    . ARG C 1 71  ? -26.373 -18.675 -39.140  1.00 47.87  ? 71  ARG C CD    1 
ATOM   8697  N  NE    . ARG C 1 71  ? -26.072 -17.345 -38.586  1.00 52.07  ? 71  ARG C NE    1 
ATOM   8698  C  CZ    . ARG C 1 71  ? -26.975 -16.465 -38.157  1.00 52.53  ? 71  ARG C CZ    1 
ATOM   8699  N  NH1   . ARG C 1 71  ? -28.244 -16.818 -38.055  1.00 55.70  ? 71  ARG C NH1   1 
ATOM   8700  N  NH2   . ARG C 1 71  ? -26.604 -15.243 -37.799  1.00 48.03  ? 71  ARG C NH2   1 
ATOM   8701  N  N     . VAL C 1 72  ? -26.190 -22.077 -43.727  1.00 45.27  ? 72  VAL C N     1 
ATOM   8702  C  CA    . VAL C 1 72  ? -26.315 -23.351 -44.433  1.00 54.14  ? 72  VAL C CA    1 
ATOM   8703  C  C     . VAL C 1 72  ? -25.261 -23.466 -45.540  1.00 55.30  ? 72  VAL C C     1 
ATOM   8704  O  O     . VAL C 1 72  ? -24.594 -24.491 -45.673  1.00 48.11  ? 72  VAL C O     1 
ATOM   8705  C  CB    . VAL C 1 72  ? -27.737 -23.507 -45.013  1.00 54.02  ? 72  VAL C CB    1 
ATOM   8706  C  CG1   . VAL C 1 72  ? -27.844 -24.675 -45.990  1.00 58.86  ? 72  VAL C CG1   1 
ATOM   8707  C  CG2   . VAL C 1 72  ? -28.781 -23.643 -43.910  1.00 52.46  ? 72  VAL C CG2   1 
ATOM   8708  N  N     . ALA C 1 73  ? -25.140 -22.419 -46.362  1.00 50.33  ? 73  ALA C N     1 
ATOM   8709  C  CA    . ALA C 1 73  ? -24.152 -22.401 -47.422  1.00 49.59  ? 73  ALA C CA    1 
ATOM   8710  C  C     . ALA C 1 73  ? -22.762 -22.689 -46.858  1.00 53.17  ? 73  ALA C C     1 
ATOM   8711  O  O     . ALA C 1 73  ? -22.024 -23.482 -47.439  1.00 56.05  ? 73  ALA C O     1 
ATOM   8712  C  CB    . ALA C 1 73  ? -24.209 -21.090 -48.142  1.00 51.35  ? 73  ALA C CB    1 
ATOM   8713  N  N     . ASN C 1 74  ? -22.413 -22.083 -45.714  1.00 50.11  ? 74  ASN C N     1 
ATOM   8714  C  CA    . ASN C 1 74  ? -21.132 -22.364 -45.073  1.00 50.53  ? 74  ASN C CA    1 
ATOM   8715  C  C     . ASN C 1 74  ? -21.059 -23.825 -44.628  1.00 54.91  ? 74  ASN C C     1 
ATOM   8716  O  O     . ASN C 1 74  ? -20.025 -24.472 -44.755  1.00 55.29  ? 74  ASN C O     1 
ATOM   8717  C  CB    . ASN C 1 74  ? -20.855 -21.474 -43.856  1.00 46.25  ? 74  ASN C CB    1 
ATOM   8718  C  CG    . ASN C 1 74  ? -20.361 -20.094 -44.245  1.00 52.04  ? 74  ASN C CG    1 
ATOM   8719  O  OD1   . ASN C 1 74  ? -19.154 -19.883 -44.392  1.00 49.24  ? 74  ASN C OD1   1 
ATOM   8720  N  ND2   . ASN C 1 74  ? -21.290 -19.185 -44.494  1.00 47.04  ? 74  ASN C ND2   1 
ATOM   8721  N  N     . GLU C 1 75  ? -22.157 -24.323 -44.060  1.00 58.60  ? 75  GLU C N     1 
ATOM   8722  C  CA    . GLU C 1 75  ? -22.168 -25.641 -43.452  1.00 68.08  ? 75  GLU C CA    1 
ATOM   8723  C  C     . GLU C 1 75  ? -21.824 -26.706 -44.494  1.00 60.48  ? 75  GLU C C     1 
ATOM   8724  O  O     . GLU C 1 75  ? -21.102 -27.640 -44.174  1.00 70.05  ? 75  GLU C O     1 
ATOM   8725  C  CB    . GLU C 1 75  ? -23.526 -25.887 -42.795  1.00 70.25  ? 75  GLU C CB    1 
ATOM   8726  C  CG    . GLU C 1 75  ? -23.616 -27.215 -42.070  1.00 72.03  ? 75  GLU C CG    1 
ATOM   8727  C  CD    . GLU C 1 75  ? -24.905 -27.399 -41.291  1.00 80.01  ? 75  GLU C CD    1 
ATOM   8728  O  OE1   . GLU C 1 75  ? -25.099 -28.504 -40.750  1.00 92.62  ? 75  GLU C OE1   1 
ATOM   8729  O  OE2   . GLU C 1 75  ? -25.714 -26.440 -41.226  1.00 74.58  ? 75  GLU C OE2   1 
ATOM   8730  N  N     . PHE C 1 76  ? -22.307 -26.532 -45.731  1.00 53.15  ? 76  PHE C N     1 
ATOM   8731  C  CA    . PHE C 1 76  ? -22.216 -27.531 -46.788  1.00 56.83  ? 76  PHE C CA    1 
ATOM   8732  C  C     . PHE C 1 76  ? -21.272 -27.129 -47.917  1.00 58.85  ? 76  PHE C C     1 
ATOM   8733  O  O     . PHE C 1 76  ? -21.097 -27.894 -48.852  1.00 59.85  ? 76  PHE C O     1 
ATOM   8734  C  CB    . PHE C 1 76  ? -23.610 -27.737 -47.373  1.00 53.13  ? 76  PHE C CB    1 
ATOM   8735  C  CG    . PHE C 1 76  ? -24.525 -28.390 -46.375  1.00 62.40  ? 76  PHE C CG    1 
ATOM   8736  C  CD1   . PHE C 1 76  ? -24.410 -29.746 -46.100  1.00 56.56  ? 76  PHE C CD1   1 
ATOM   8737  C  CD2   . PHE C 1 76  ? -25.446 -27.639 -45.658  1.00 61.64  ? 76  PHE C CD2   1 
ATOM   8738  C  CE1   . PHE C 1 76  ? -25.242 -30.346 -45.168  1.00 60.31  ? 76  PHE C CE1   1 
ATOM   8739  C  CE2   . PHE C 1 76  ? -26.266 -28.238 -44.717  1.00 62.19  ? 76  PHE C CE2   1 
ATOM   8740  C  CZ    . PHE C 1 76  ? -26.169 -29.592 -44.480  1.00 63.76  ? 76  PHE C CZ    1 
ATOM   8741  N  N     . GLY C 1 77  ? -20.722 -25.912 -47.850  1.00 65.18  ? 77  GLY C N     1 
ATOM   8742  C  CA    . GLY C 1 77  ? -19.760 -25.426 -48.820  1.00 58.76  ? 77  GLY C CA    1 
ATOM   8743  C  C     . GLY C 1 77  ? -20.406 -25.171 -50.172  1.00 59.16  ? 77  GLY C C     1 
ATOM   8744  O  O     . GLY C 1 77  ? -19.748 -25.327 -51.194  1.00 65.85  ? 77  GLY C O     1 
ATOM   8745  N  N     . VAL C 1 78  ? -21.678 -24.758 -50.163  1.00 53.50  ? 78  VAL C N     1 
ATOM   8746  C  CA    . VAL C 1 78  ? -22.418 -24.500 -51.384  1.00 49.83  ? 78  VAL C CA    1 
ATOM   8747  C  C     . VAL C 1 78  ? -22.428 -22.999 -51.693  1.00 60.78  ? 78  VAL C C     1 
ATOM   8748  O  O     . VAL C 1 78  ? -22.941 -22.194 -50.906  1.00 56.07  ? 78  VAL C O     1 
ATOM   8749  C  CB    . VAL C 1 78  ? -23.855 -25.023 -51.251  1.00 52.06  ? 78  VAL C CB    1 
ATOM   8750  C  CG1   . VAL C 1 78  ? -24.746 -24.486 -52.366  1.00 51.25  ? 78  VAL C CG1   1 
ATOM   8751  C  CG2   . VAL C 1 78  ? -23.877 -26.540 -51.183  1.00 56.58  ? 78  VAL C CG2   1 
ATOM   8752  N  N     . PRO C 1 79  ? -21.900 -22.571 -52.867  1.00 57.54  ? 79  PRO C N     1 
ATOM   8753  C  CA    . PRO C 1 79  ? -21.767 -21.150 -53.176  1.00 51.24  ? 79  PRO C CA    1 
ATOM   8754  C  C     . PRO C 1 79  ? -23.063 -20.525 -53.675  1.00 49.47  ? 79  PRO C C     1 
ATOM   8755  O  O     . PRO C 1 79  ? -23.925 -21.211 -54.221  1.00 47.73  ? 79  PRO C O     1 
ATOM   8756  C  CB    . PRO C 1 79  ? -20.664 -21.090 -54.253  1.00 53.94  ? 79  PRO C CB    1 
ATOM   8757  C  CG    . PRO C 1 79  ? -20.595 -22.488 -54.863  1.00 53.00  ? 79  PRO C CG    1 
ATOM   8758  C  CD    . PRO C 1 79  ? -21.315 -23.429 -53.914  1.00 57.24  ? 79  PRO C CD    1 
ATOM   8759  N  N     . LEU C 1 80  ? -23.177 -19.205 -53.449  1.00 44.69  ? 80  LEU C N     1 
ATOM   8760  C  CA    . LEU C 1 80  ? -24.388 -18.438 -53.689  1.00 44.24  ? 80  LEU C CA    1 
ATOM   8761  C  C     . LEU C 1 80  ? -24.066 -17.296 -54.630  1.00 45.04  ? 80  LEU C C     1 
ATOM   8762  O  O     . LEU C 1 80  ? -22.960 -16.779 -54.571  1.00 45.27  ? 80  LEU C O     1 
ATOM   8763  C  CB    . LEU C 1 80  ? -24.865 -17.849 -52.357  1.00 48.87  ? 80  LEU C CB    1 
ATOM   8764  C  CG    . LEU C 1 80  ? -25.331 -18.851 -51.308  1.00 43.47  ? 80  LEU C CG    1 
ATOM   8765  C  CD1   . LEU C 1 80  ? -25.627 -18.160 -49.984  1.00 50.06  ? 80  LEU C CD1   1 
ATOM   8766  C  CD2   . LEU C 1 80  ? -26.578 -19.552 -51.792  1.00 48.87  ? 80  LEU C CD2   1 
ATOM   8767  N  N     . TRP C 1 81  ? -25.041 -16.868 -55.439  1.00 45.97  ? 81  TRP C N     1 
ATOM   8768  C  CA    . TRP C 1 81  ? -24.854 -15.714 -56.298  1.00 47.70  ? 81  TRP C CA    1 
ATOM   8769  C  C     . TRP C 1 81  ? -25.953 -14.702 -56.002  1.00 47.70  ? 81  TRP C C     1 
ATOM   8770  O  O     . TRP C 1 81  ? -27.047 -14.804 -56.536  1.00 48.37  ? 81  TRP C O     1 
ATOM   8771  C  CB    . TRP C 1 81  ? -24.817 -16.089 -57.788  1.00 47.42  ? 81  TRP C CB    1 
ATOM   8772  C  CG    . TRP C 1 81  ? -24.377 -14.944 -58.644  1.00 49.00  ? 81  TRP C CG    1 
ATOM   8773  C  CD1   . TRP C 1 81  ? -25.145 -13.950 -59.178  1.00 51.27  ? 81  TRP C CD1   1 
ATOM   8774  C  CD2   . TRP C 1 81  ? -23.021 -14.647 -59.008  1.00 47.32  ? 81  TRP C CD2   1 
ATOM   8775  N  NE1   . TRP C 1 81  ? -24.362 -13.053 -59.849  1.00 50.22  ? 81  TRP C NE1   1 
ATOM   8776  C  CE2   . TRP C 1 81  ? -23.055 -13.469 -59.773  1.00 50.29  ? 81  TRP C CE2   1 
ATOM   8777  C  CE3   . TRP C 1 81  ? -21.801 -15.285 -58.779  1.00 50.30  ? 81  TRP C CE3   1 
ATOM   8778  C  CZ2   . TRP C 1 81  ? -21.897 -12.902 -60.288  1.00 49.63  ? 81  TRP C CZ2   1 
ATOM   8779  C  CZ3   . TRP C 1 81  ? -20.658 -14.733 -59.303  1.00 45.48  ? 81  TRP C CZ3   1 
ATOM   8780  C  CH2   . TRP C 1 81  ? -20.712 -13.548 -60.023  1.00 49.10  ? 81  TRP C CH2   1 
ATOM   8781  N  N     . PRO C 1 82  ? -25.682 -13.675 -55.171  1.00 49.32  ? 82  PRO C N     1 
ATOM   8782  C  CA    . PRO C 1 82  ? -26.714 -12.737 -54.751  1.00 47.83  ? 82  PRO C CA    1 
ATOM   8783  C  C     . PRO C 1 82  ? -27.086 -11.816 -55.889  1.00 53.00  ? 82  PRO C C     1 
ATOM   8784  O  O     . PRO C 1 82  ? -26.213 -11.236 -56.526  1.00 54.81  ? 82  PRO C O     1 
ATOM   8785  C  CB    . PRO C 1 82  ? -26.054 -11.931 -53.631  1.00 46.71  ? 82  PRO C CB    1 
ATOM   8786  C  CG    . PRO C 1 82  ? -24.869 -12.775 -53.220  1.00 49.56  ? 82  PRO C CG    1 
ATOM   8787  C  CD    . PRO C 1 82  ? -24.397 -13.400 -54.516  1.00 49.50  ? 82  PRO C CD    1 
ATOM   8788  N  N     . VAL C 1 83  ? -28.387 -11.731 -56.137  1.00 51.20  ? 83  VAL C N     1 
ATOM   8789  C  CA    . VAL C 1 83  ? -28.913 -10.761 -57.068  1.00 54.02  ? 83  VAL C CA    1 
ATOM   8790  C  C     . VAL C 1 83  ? -30.013 -10.004 -56.347  1.00 53.94  ? 83  VAL C C     1 
ATOM   8791  O  O     . VAL C 1 83  ? -30.742 -10.592 -55.550  1.00 51.17  ? 83  VAL C O     1 
ATOM   8792  C  CB    . VAL C 1 83  ? -29.415 -11.421 -58.360  1.00 52.31  ? 83  VAL C CB    1 
ATOM   8793  C  CG1   . VAL C 1 83  ? -28.279 -12.129 -59.062  1.00 53.52  ? 83  VAL C CG1   1 
ATOM   8794  C  CG2   . VAL C 1 83  ? -30.568 -12.376 -58.118  1.00 56.53  ? 83  VAL C CG2   1 
ATOM   8795  N  N     . SER C 1 84  ? -30.082 -8.697  -56.609  1.00 48.75  ? 84  SER C N     1 
ATOM   8796  C  CA    . SER C 1 84  ? -31.101 -7.881  -55.993  1.00 48.88  ? 84  SER C CA    1 
ATOM   8797  C  C     . SER C 1 84  ? -32.412 -8.128  -56.730  1.00 51.53  ? 84  SER C C     1 
ATOM   8798  O  O     . SER C 1 84  ? -33.427 -8.460  -56.115  1.00 48.82  ? 84  SER C O     1 
ATOM   8799  C  CB    . SER C 1 84  ? -30.687 -6.435  -55.964  1.00 54.58  ? 84  SER C CB    1 
ATOM   8800  O  OG    . SER C 1 84  ? -29.540 -6.274  -55.123  1.00 53.24  ? 84  SER C OG    1 
ATOM   8801  N  N     . ARG C 1 85  ? -32.352 -7.954  -58.053  1.00 49.13  ? 85  ARG C N     1 
ATOM   8802  C  CA    . ARG C 1 85  ? -33.451 -8.242  -58.959  1.00 54.24  ? 85  ARG C CA    1 
ATOM   8803  C  C     . ARG C 1 85  ? -32.971 -9.079  -60.139  1.00 56.35  ? 85  ARG C C     1 
ATOM   8804  O  O     . ARG C 1 85  ? -33.790 -9.680  -60.826  1.00 62.37  ? 85  ARG C O     1 
ATOM   8805  C  CB    . ARG C 1 85  ? -34.072 -6.951  -59.489  1.00 51.71  ? 85  ARG C CB    1 
ATOM   8806  C  CG    . ARG C 1 85  ? -35.033 -6.295  -58.513  1.00 52.43  ? 85  ARG C CG    1 
ATOM   8807  C  CD    . ARG C 1 85  ? -35.588 -4.999  -59.046  1.00 55.88  ? 85  ARG C CD    1 
ATOM   8808  N  NE    . ARG C 1 85  ? -36.214 -5.180  -60.339  1.00 59.73  ? 85  ARG C NE    1 
ATOM   8809  C  CZ    . ARG C 1 85  ? -37.499 -5.465  -60.520  1.00 59.70  ? 85  ARG C CZ    1 
ATOM   8810  N  NH1   . ARG C 1 85  ? -38.270 -5.732  -59.487  1.00 57.17  ? 85  ARG C NH1   1 
ATOM   8811  N  NH2   . ARG C 1 85  ? -37.993 -5.530  -61.743  1.00 59.42  ? 85  ARG C NH2   1 
ATOM   8812  N  N     . GLY C 1 86  ? -31.658 -9.049  -60.406  1.00 58.53  ? 86  GLY C N     1 
ATOM   8813  C  CA    . GLY C 1 86  ? -31.043 -9.923  -61.389  1.00 61.76  ? 86  GLY C CA    1 
ATOM   8814  C  C     . GLY C 1 86  ? -31.373 -9.492  -62.813  1.00 61.08  ? 86  GLY C C     1 
ATOM   8815  O  O     . GLY C 1 86  ? -31.496 -10.340 -63.703  1.00 63.34  ? 86  GLY C O     1 
ATOM   8816  N  N     . LYS C 1 87  ? -31.509 -8.169  -63.002  1.00 55.37  ? 87  LYS C N     1 
ATOM   8817  C  CA    . LYS C 1 87  ? -31.866 -7.625  -64.303  1.00 61.63  ? 87  LYS C CA    1 
ATOM   8818  C  C     . LYS C 1 87  ? -30.619 -7.036  -64.952  1.00 56.78  ? 87  LYS C C     1 
ATOM   8819  O  O     . LYS C 1 87  ? -30.738 -6.079  -65.712  1.00 60.53  ? 87  LYS C O     1 
ATOM   8820  C  CB    . LYS C 1 87  ? -32.962 -6.555  -64.191  1.00 66.87  ? 87  LYS C CB    1 
ATOM   8821  C  CG    . LYS C 1 87  ? -34.231 -6.990  -63.464  1.00 68.16  ? 87  LYS C CG    1 
ATOM   8822  C  CD    . LYS C 1 87  ? -34.802 -8.305  -63.967  1.00 62.48  ? 87  LYS C CD    1 
ATOM   8823  C  CE    . LYS C 1 87  ? -36.191 -8.590  -63.438  1.00 66.62  ? 87  LYS C CE    1 
ATOM   8824  N  NZ    . LYS C 1 87  ? -36.499 -10.037 -63.521  1.00 67.06  ? 87  LYS C NZ    1 
ATOM   8825  N  N     . ASN C 1 88  ? -29.436 -7.618  -64.670  1.00 59.26  ? 88  ASN C N     1 
ATOM   8826  C  CA    . ASN C 1 88  ? -28.171 -7.031  -65.115  1.00 63.89  ? 88  ASN C CA    1 
ATOM   8827  C  C     . ASN C 1 88  ? -27.922 -7.391  -66.586  1.00 67.38  ? 88  ASN C C     1 
ATOM   8828  O  O     . ASN C 1 88  ? -26.856 -7.902  -66.955  1.00 66.32  ? 88  ASN C O     1 
ATOM   8829  C  CB    . ASN C 1 88  ? -27.013 -7.425  -64.192  1.00 60.85  ? 88  ASN C CB    1 
ATOM   8830  C  CG    . ASN C 1 88  ? -25.887 -6.408  -64.143  1.00 57.81  ? 88  ASN C CG    1 
ATOM   8831  O  OD1   . ASN C 1 88  ? -25.996 -5.312  -64.687  1.00 60.55  ? 88  ASN C OD1   1 
ATOM   8832  N  ND2   . ASN C 1 88  ? -24.802 -6.750  -63.467  1.00 61.44  ? 88  ASN C ND2   1 
ATOM   8833  N  N     . PHE C 1 89  ? -28.927 -7.092  -67.424  1.00 61.86  ? 89  PHE C N     1 
ATOM   8834  C  CA    . PHE C 1 89  ? -28.875 -7.388  -68.844  1.00 66.57  ? 89  PHE C CA    1 
ATOM   8835  C  C     . PHE C 1 89  ? -27.688 -6.619  -69.432  1.00 65.94  ? 89  PHE C C     1 
ATOM   8836  O  O     . PHE C 1 89  ? -27.569 -5.409  -69.199  1.00 61.32  ? 89  PHE C O     1 
ATOM   8837  C  CB    . PHE C 1 89  ? -30.234 -7.067  -69.483  1.00 67.80  ? 89  PHE C CB    1 
ATOM   8838  C  CG    . PHE C 1 89  ? -31.439 -7.675  -68.796  1.00 70.31  ? 89  PHE C CG    1 
ATOM   8839  C  CD1   . PHE C 1 89  ? -31.396 -8.961  -68.263  1.00 70.24  ? 89  PHE C CD1   1 
ATOM   8840  C  CD2   . PHE C 1 89  ? -32.631 -6.968  -68.695  1.00 71.32  ? 89  PHE C CD2   1 
ATOM   8841  C  CE1   . PHE C 1 89  ? -32.505 -9.512  -67.631  1.00 72.72  ? 89  PHE C CE1   1 
ATOM   8842  C  CE2   . PHE C 1 89  ? -33.744 -7.524  -68.074  1.00 71.14  ? 89  PHE C CE2   1 
ATOM   8843  C  CZ    . PHE C 1 89  ? -33.683 -8.798  -67.549  1.00 68.76  ? 89  PHE C CZ    1 
ATOM   8844  N  N     . ALA C 1 90  ? -26.787 -7.343  -70.126  1.00 58.76  ? 90  ALA C N     1 
ATOM   8845  C  CA    . ALA C 1 90  ? -25.609 -6.773  -70.782  1.00 58.78  ? 90  ALA C CA    1 
ATOM   8846  C  C     . ALA C 1 90  ? -24.355 -7.195  -70.042  1.00 60.04  ? 90  ALA C C     1 
ATOM   8847  O  O     . ALA C 1 90  ? -23.246 -7.065  -70.585  1.00 56.86  ? 90  ALA C O     1 
ATOM   8848  C  CB    . ALA C 1 90  ? -25.621 -5.258  -70.830  1.00 61.85  ? 90  ALA C CB    1 
ATOM   8849  N  N     . TYR C 1 91  ? -24.568 -7.578  -68.772  1.00 57.70  ? 91  TYR C N     1 
ATOM   8850  C  CA    . TYR C 1 91  ? -23.493 -7.955  -67.876  1.00 60.96  ? 91  TYR C CA    1 
ATOM   8851  C  C     . TYR C 1 91  ? -23.720 -9.367  -67.330  1.00 55.73  ? 91  TYR C C     1 
ATOM   8852  O  O     . TYR C 1 91  ? -22.934 -9.833  -66.516  1.00 58.79  ? 91  TYR C O     1 
ATOM   8853  C  CB    . TYR C 1 91  ? -23.308 -6.880  -66.796  1.00 60.23  ? 91  TYR C CB    1 
ATOM   8854  C  CG    . TYR C 1 91  ? -22.919 -5.527  -67.341  1.00 60.57  ? 91  TYR C CG    1 
ATOM   8855  C  CD1   . TYR C 1 91  ? -21.821 -5.371  -68.176  1.00 65.19  ? 91  TYR C CD1   1 
ATOM   8856  C  CD2   . TYR C 1 91  ? -23.662 -4.400  -67.051  1.00 61.10  ? 91  TYR C CD2   1 
ATOM   8857  C  CE1   . TYR C 1 91  ? -21.477 -4.134  -68.702  1.00 63.61  ? 91  TYR C CE1   1 
ATOM   8858  C  CE2   . TYR C 1 91  ? -23.333 -3.157  -67.566  1.00 62.12  ? 91  TYR C CE2   1 
ATOM   8859  C  CZ    . TYR C 1 91  ? -22.233 -3.018  -68.390  1.00 59.51  ? 91  TYR C CZ    1 
ATOM   8860  O  OH    . TYR C 1 91  ? -21.933 -1.769  -68.894  1.00 64.94  ? 91  TYR C OH    1 
ATOM   8861  N  N     . GLY C 1 92  ? -24.727 -10.078 -67.851  1.00 60.59  ? 92  GLY C N     1 
ATOM   8862  C  CA    . GLY C 1 92  ? -24.907 -11.493 -67.567  1.00 56.84  ? 92  GLY C CA    1 
ATOM   8863  C  C     . GLY C 1 92  ? -26.293 -11.832 -67.022  1.00 62.22  ? 92  GLY C C     1 
ATOM   8864  O  O     . GLY C 1 92  ? -26.591 -13.011 -66.816  1.00 58.60  ? 92  GLY C O     1 
ATOM   8865  N  N     . GLY C 1 93  ? -27.138 -10.810 -66.798  1.00 62.45  ? 93  GLY C N     1 
ATOM   8866  C  CA    . GLY C 1 93  ? -28.423 -11.012 -66.142  1.00 64.34  ? 93  GLY C CA    1 
ATOM   8867  C  C     . GLY C 1 93  ? -28.236 -11.508 -64.707  1.00 61.10  ? 93  GLY C C     1 
ATOM   8868  O  O     . GLY C 1 93  ? -27.413 -10.959 -63.975  1.00 62.33  ? 93  GLY C O     1 
ATOM   8869  N  N     . ALA C 1 94  ? -28.943 -12.589 -64.339  1.00 63.97  ? 94  ALA C N     1 
ATOM   8870  C  CA    . ALA C 1 94  ? -28.872 -13.155 -62.995  1.00 65.27  ? 94  ALA C CA    1 
ATOM   8871  C  C     . ALA C 1 94  ? -27.839 -14.282 -62.885  1.00 64.51  ? 94  ALA C C     1 
ATOM   8872  O  O     . ALA C 1 94  ? -27.647 -14.832 -61.795  1.00 63.58  ? 94  ALA C O     1 
ATOM   8873  C  CB    . ALA C 1 94  ? -30.241 -13.643 -62.582  1.00 64.77  ? 94  ALA C CB    1 
ATOM   8874  N  N     . ALA C 1 95  ? -27.156 -14.614 -63.992  1.00 62.39  ? 95  ALA C N     1 
ATOM   8875  C  CA    . ALA C 1 95  ? -26.309 -15.803 -64.057  1.00 63.75  ? 95  ALA C CA    1 
ATOM   8876  C  C     . ALA C 1 95  ? -25.019 -15.625 -63.253  1.00 57.88  ? 95  ALA C C     1 
ATOM   8877  O  O     . ALA C 1 95  ? -24.468 -14.534 -63.182  1.00 60.32  ? 95  ALA C O     1 
ATOM   8878  C  CB    . ALA C 1 95  ? -26.017 -16.146 -65.503  1.00 63.95  ? 95  ALA C CB    1 
ATOM   8879  N  N     . PRO C 1 96  ? -24.478 -16.700 -62.633  1.00 60.12  ? 96  PRO C N     1 
ATOM   8880  C  CA    . PRO C 1 96  ? -23.166 -16.651 -61.986  1.00 60.40  ? 96  PRO C CA    1 
ATOM   8881  C  C     . PRO C 1 96  ? -21.977 -16.859 -62.925  1.00 65.42  ? 96  PRO C C     1 
ATOM   8882  O  O     . PRO C 1 96  ? -22.115 -17.504 -63.960  1.00 71.54  ? 96  PRO C O     1 
ATOM   8883  C  CB    . PRO C 1 96  ? -23.233 -17.864 -61.045  1.00 62.21  ? 96  PRO C CB    1 
ATOM   8884  C  CG    . PRO C 1 96  ? -24.039 -18.880 -61.840  1.00 59.80  ? 96  PRO C CG    1 
ATOM   8885  C  CD    . PRO C 1 96  ? -25.098 -18.035 -62.520  1.00 61.39  ? 96  PRO C CD    1 
ATOM   8886  N  N     . VAL C 1 97  ? -20.808 -16.332 -62.525  1.00 56.94  ? 97  VAL C N     1 
ATOM   8887  C  CA    . VAL C 1 97  ? -19.541 -16.601 -63.184  1.00 54.67  ? 97  VAL C CA    1 
ATOM   8888  C  C     . VAL C 1 97  ? -19.350 -18.109 -63.265  1.00 56.81  ? 97  VAL C C     1 
ATOM   8889  O  O     . VAL C 1 97  ? -19.141 -18.647 -64.351  1.00 55.42  ? 97  VAL C O     1 
ATOM   8890  C  CB    . VAL C 1 97  ? -18.375 -15.933 -62.432  1.00 53.86  ? 97  VAL C CB    1 
ATOM   8891  C  CG1   . VAL C 1 97  ? -17.023 -16.512 -62.819  1.00 57.72  ? 97  VAL C CG1   1 
ATOM   8892  C  CG2   . VAL C 1 97  ? -18.397 -14.414 -62.602  1.00 53.64  ? 97  VAL C CG2   1 
ATOM   8893  N  N     . MET C 1 98  ? -19.452 -18.751 -62.097  1.00 51.51  ? 98  MET C N     1 
ATOM   8894  C  CA    . MET C 1 98  ? -19.130 -20.153 -61.952  1.00 57.65  ? 98  MET C CA    1 
ATOM   8895  C  C     . MET C 1 98  ? -20.424 -20.965 -61.975  1.00 73.92  ? 98  MET C C     1 
ATOM   8896  O  O     . MET C 1 98  ? -21.384 -20.657 -61.265  1.00 78.78  ? 98  MET C O     1 
ATOM   8897  C  CB    . MET C 1 98  ? -18.379 -20.400 -60.643  1.00 59.30  ? 98  MET C CB    1 
ATOM   8898  C  CG    . MET C 1 98  ? -17.759 -21.783 -60.548  1.00 57.49  ? 98  MET C CG    1 
ATOM   8899  S  SD    . MET C 1 98  ? -16.965 -22.127 -58.948  1.00 67.43  ? 98  MET C SD    1 
ATOM   8900  C  CE    . MET C 1 98  ? -18.447 -22.355 -57.958  1.00 71.70  ? 98  MET C CE    1 
ATOM   8901  N  N     . SER C 1 99  ? -20.428 -22.001 -62.824  1.00 67.72  ? 99  SER C N     1 
ATOM   8902  C  CA    . SER C 1 99  ? -21.516 -22.958 -62.926  1.00 60.45  ? 99  SER C CA    1 
ATOM   8903  C  C     . SER C 1 99  ? -21.713 -23.715 -61.612  1.00 52.74  ? 99  SER C C     1 
ATOM   8904  O  O     . SER C 1 99  ? -20.772 -23.985 -60.860  1.00 55.39  ? 99  SER C O     1 
ATOM   8905  C  CB    . SER C 1 99  ? -21.257 -23.906 -64.075  1.00 59.78  ? 99  SER C CB    1 
ATOM   8906  O  OG    . SER C 1 99  ? -21.308 -23.199 -65.313  1.00 59.97  ? 99  SER C OG    1 
ATOM   8907  N  N     . GLY C 1 100 ? -22.968 -24.030 -61.313  1.00 50.25  ? 100 GLY C N     1 
ATOM   8908  C  CA    . GLY C 1 100 ? -23.280 -24.769 -60.099  1.00 56.61  ? 100 GLY C CA    1 
ATOM   8909  C  C     . GLY C 1 100 ? -23.510 -23.867 -58.885  1.00 58.21  ? 100 GLY C C     1 
ATOM   8910  O  O     . GLY C 1 100 ? -23.874 -24.369 -57.825  1.00 56.89  ? 100 GLY C O     1 
ATOM   8911  N  N     . THR C 1 101 ? -23.273 -22.552 -59.043  1.00 62.11  ? 101 THR C N     1 
ATOM   8912  C  CA    . THR C 1 101 ? -23.576 -21.553 -58.024  1.00 56.28  ? 101 THR C CA    1 
ATOM   8913  C  C     . THR C 1 101 ? -25.091 -21.446 -57.852  1.00 56.92  ? 101 THR C C     1 
ATOM   8914  O  O     . THR C 1 101 ? -25.815 -21.478 -58.841  1.00 68.44  ? 101 THR C O     1 
ATOM   8915  C  CB    . THR C 1 101 ? -22.962 -20.197 -58.409  1.00 56.49  ? 101 THR C CB    1 
ATOM   8916  O  OG1   . THR C 1 101 ? -21.544 -20.315 -58.526  1.00 46.31  ? 101 THR C OG1   1 
ATOM   8917  C  CG2   . THR C 1 101 ? -23.225 -19.115 -57.392  1.00 61.60  ? 101 THR C CG2   1 
ATOM   8918  N  N     . VAL C 1 102 ? -25.569 -21.342 -56.598  1.00 56.42  ? 102 VAL C N     1 
ATOM   8919  C  CA    . VAL C 1 102 ? -26.992 -21.195 -56.309  1.00 49.74  ? 102 VAL C CA    1 
ATOM   8920  C  C     . VAL C 1 102 ? -27.359 -19.714 -56.246  1.00 49.27  ? 102 VAL C C     1 
ATOM   8921  O  O     . VAL C 1 102 ? -26.828 -18.973 -55.430  1.00 56.53  ? 102 VAL C O     1 
ATOM   8922  C  CB    . VAL C 1 102 ? -27.361 -21.900 -54.995  1.00 47.09  ? 102 VAL C CB    1 
ATOM   8923  C  CG1   . VAL C 1 102 ? -28.809 -21.635 -54.602  1.00 51.93  ? 102 VAL C CG1   1 
ATOM   8924  C  CG2   . VAL C 1 102 ? -27.106 -23.393 -55.068  1.00 52.16  ? 102 VAL C CG2   1 
ATOM   8925  N  N     . VAL C 1 103 ? -28.303 -19.285 -57.075  1.00 48.92  ? 103 VAL C N     1 
ATOM   8926  C  CA    . VAL C 1 103 ? -28.658 -17.882 -57.125  1.00 52.82  ? 103 VAL C CA    1 
ATOM   8927  C  C     . VAL C 1 103 ? -29.445 -17.542 -55.865  1.00 59.31  ? 103 VAL C C     1 
ATOM   8928  O  O     . VAL C 1 103 ? -30.404 -18.231 -55.532  1.00 54.27  ? 103 VAL C O     1 
ATOM   8929  C  CB    . VAL C 1 103 ? -29.461 -17.520 -58.382  1.00 54.23  ? 103 VAL C CB    1 
ATOM   8930  C  CG1   . VAL C 1 103 ? -30.024 -16.108 -58.275  1.00 59.41  ? 103 VAL C CG1   1 
ATOM   8931  C  CG2   . VAL C 1 103 ? -28.626 -17.680 -59.647  1.00 54.43  ? 103 VAL C CG2   1 
ATOM   8932  N  N     . LEU C 1 104 ? -29.004 -16.482 -55.178  1.00 51.64  ? 104 LEU C N     1 
ATOM   8933  C  CA    . LEU C 1 104 ? -29.704 -15.940 -54.031  1.00 46.98  ? 104 LEU C CA    1 
ATOM   8934  C  C     . LEU C 1 104 ? -30.433 -14.697 -54.502  1.00 47.37  ? 104 LEU C C     1 
ATOM   8935  O  O     . LEU C 1 104 ? -29.844 -13.623 -54.632  1.00 46.61  ? 104 LEU C O     1 
ATOM   8936  C  CB    . LEU C 1 104 ? -28.696 -15.663 -52.917  1.00 52.46  ? 104 LEU C CB    1 
ATOM   8937  C  CG    . LEU C 1 104 ? -29.242 -14.986 -51.661  1.00 55.48  ? 104 LEU C CG    1 
ATOM   8938  C  CD1   . LEU C 1 104 ? -30.306 -15.826 -50.976  1.00 55.27  ? 104 LEU C CD1   1 
ATOM   8939  C  CD2   . LEU C 1 104 ? -28.106 -14.713 -50.698  1.00 55.88  ? 104 LEU C CD2   1 
ATOM   8940  N  N     . ASP C 1 105 ? -31.730 -14.893 -54.772  1.00 45.36  ? 105 ASP C N     1 
ATOM   8941  C  CA    . ASP C 1 105 ? -32.555 -13.927 -55.472  1.00 52.51  ? 105 ASP C CA    1 
ATOM   8942  C  C     . ASP C 1 105 ? -33.349 -13.132 -54.448  1.00 53.66  ? 105 ASP C C     1 
ATOM   8943  O  O     . ASP C 1 105 ? -34.225 -13.686 -53.787  1.00 52.16  ? 105 ASP C O     1 
ATOM   8944  C  CB    . ASP C 1 105 ? -33.516 -14.625 -56.442  1.00 50.55  ? 105 ASP C CB    1 
ATOM   8945  C  CG    . ASP C 1 105 ? -34.498 -13.687 -57.119  1.00 49.75  ? 105 ASP C CG    1 
ATOM   8946  O  OD1   . ASP C 1 105 ? -34.409 -12.464 -56.893  1.00 52.23  ? 105 ASP C OD1   1 
ATOM   8947  O  OD2   . ASP C 1 105 ? -35.332 -14.190 -57.888  1.00 54.87  ? 105 ASP C OD2   1 
ATOM   8948  N  N     . MET C 1 106 ? -33.095 -11.822 -54.359  1.00 47.87  ? 106 MET C N     1 
ATOM   8949  C  CA    . MET C 1 106 ? -33.706 -11.077 -53.275  1.00 49.07  ? 106 MET C CA    1 
ATOM   8950  C  C     . MET C 1 106 ? -34.880 -10.233 -53.761  1.00 41.75  ? 106 MET C C     1 
ATOM   8951  O  O     . MET C 1 106 ? -35.296 -9.321  -53.076  1.00 44.56  ? 106 MET C O     1 
ATOM   8952  C  CB    . MET C 1 106 ? -32.635 -10.266 -52.559  1.00 52.10  ? 106 MET C CB    1 
ATOM   8953  C  CG    . MET C 1 106 ? -31.868 -11.153 -51.575  1.00 54.15  ? 106 MET C CG    1 
ATOM   8954  S  SD    . MET C 1 106 ? -30.531 -10.297 -50.751  1.00 59.63  ? 106 MET C SD    1 
ATOM   8955  C  CE    . MET C 1 106 ? -29.602 -9.779  -52.197  1.00 62.94  ? 106 MET C CE    1 
ATOM   8956  N  N     . ASN C 1 107 ? -35.474 -10.624 -54.890  1.00 41.29  ? 107 ASN C N     1 
ATOM   8957  C  CA    . ASN C 1 107 ? -36.613 -9.936  -55.479  1.00 48.40  ? 107 ASN C CA    1 
ATOM   8958  C  C     . ASN C 1 107 ? -37.786 -9.713  -54.521  1.00 43.12  ? 107 ASN C C     1 
ATOM   8959  O  O     . ASN C 1 107 ? -38.471 -8.707  -54.643  1.00 44.91  ? 107 ASN C O     1 
ATOM   8960  C  CB    . ASN C 1 107 ? -37.160 -10.727 -56.664  1.00 55.93  ? 107 ASN C CB    1 
ATOM   8961  C  CG    . ASN C 1 107 ? -36.579 -10.257 -57.973  1.00 66.14  ? 107 ASN C CG    1 
ATOM   8962  O  OD1   . ASN C 1 107 ? -35.754 -10.939 -58.576  1.00 79.89  ? 107 ASN C OD1   1 
ATOM   8963  N  ND2   . ASN C 1 107 ? -36.987 -9.077  -58.397  1.00 68.97  ? 107 ASN C ND2   1 
ATOM   8964  N  N     . ARG C 1 108 ? -38.096 -10.702 -53.676  1.00 46.10  ? 108 ARG C N     1 
ATOM   8965  C  CA    . ARG C 1 108 ? -39.238 -10.634 -52.763  1.00 49.94  ? 108 ARG C CA    1 
ATOM   8966  C  C     . ARG C 1 108 ? -39.001 -9.599  -51.665  1.00 51.51  ? 108 ARG C C     1 
ATOM   8967  O  O     . ARG C 1 108 ? -39.952 -9.126  -51.036  1.00 48.27  ? 108 ARG C O     1 
ATOM   8968  C  CB    . ARG C 1 108 ? -39.499 -11.991 -52.095  1.00 49.26  ? 108 ARG C CB    1 
ATOM   8969  C  CG    . ARG C 1 108 ? -39.780 -13.126 -53.077  1.00 48.76  ? 108 ARG C CG    1 
ATOM   8970  C  CD    . ARG C 1 108 ? -39.763 -14.478 -52.386  1.00 50.86  ? 108 ARG C CD    1 
ATOM   8971  N  NE    . ARG C 1 108 ? -40.918 -14.589 -51.503  1.00 54.01  ? 108 ARG C NE    1 
ATOM   8972  C  CZ    . ARG C 1 108 ? -40.926 -15.146 -50.298  1.00 47.87  ? 108 ARG C CZ    1 
ATOM   8973  N  NH1   . ARG C 1 108 ? -39.938 -15.918 -49.904  1.00 47.77  ? 108 ARG C NH1   1 
ATOM   8974  N  NH2   . ARG C 1 108 ? -41.985 -15.001 -49.525  1.00 53.13  ? 108 ARG C NH2   1 
ATOM   8975  N  N     . MET C 1 109 ? -37.725 -9.272  -51.416  1.00 46.14  ? 109 MET C N     1 
ATOM   8976  C  CA    . MET C 1 109 ? -37.362 -8.246  -50.448  1.00 41.62  ? 109 MET C CA    1 
ATOM   8977  C  C     . MET C 1 109 ? -37.455 -6.899  -51.150  1.00 42.79  ? 109 MET C C     1 
ATOM   8978  O  O     . MET C 1 109 ? -36.446 -6.321  -51.572  1.00 44.07  ? 109 MET C O     1 
ATOM   8979  C  CB    . MET C 1 109 ? -35.960 -8.538  -49.903  1.00 45.20  ? 109 MET C CB    1 
ATOM   8980  C  CG    . MET C 1 109 ? -35.964 -9.780  -48.988  1.00 45.36  ? 109 MET C CG    1 
ATOM   8981  S  SD    . MET C 1 109 ? -34.336 -10.428 -48.530  1.00 47.88  ? 109 MET C SD    1 
ATOM   8982  C  CE    . MET C 1 109 ? -33.736 -8.977  -47.658  1.00 45.98  ? 109 MET C CE    1 
ATOM   8983  N  N     . ASN C 1 110 ? -38.707 -6.460  -51.357  1.00 44.42  ? 110 ASN C N     1 
ATOM   8984  C  CA    . ASN C 1 110 ? -38.988 -5.315  -52.208  1.00 46.24  ? 110 ASN C CA    1 
ATOM   8985  C  C     . ASN C 1 110 ? -39.724 -4.217  -51.441  1.00 38.44  ? 110 ASN C C     1 
ATOM   8986  O  O     . ASN C 1 110 ? -40.498 -3.486  -52.035  1.00 40.35  ? 110 ASN C O     1 
ATOM   8987  C  CB    . ASN C 1 110 ? -39.831 -5.702  -53.421  1.00 48.44  ? 110 ASN C CB    1 
ATOM   8988  C  CG    . ASN C 1 110 ? -41.237 -6.086  -53.016  1.00 49.56  ? 110 ASN C CG    1 
ATOM   8989  O  OD1   . ASN C 1 110 ? -41.481 -6.501  -51.888  1.00 43.71  ? 110 ASN C OD1   1 
ATOM   8990  N  ND2   . ASN C 1 110 ? -42.173 -5.916  -53.919  1.00 52.52  ? 110 ASN C ND2   1 
ATOM   8991  N  N     . ARG C 1 111 ? -39.455 -4.070  -50.146  1.00 42.97  ? 111 ARG C N     1 
ATOM   8992  C  CA    . ARG C 1 111 ? -40.088 -3.007  -49.383  1.00 45.27  ? 111 ARG C CA    1 
ATOM   8993  C  C     . ARG C 1 111 ? -39.311 -1.710  -49.583  1.00 44.97  ? 111 ARG C C     1 
ATOM   8994  O  O     . ARG C 1 111 ? -38.084 -1.710  -49.521  1.00 40.40  ? 111 ARG C O     1 
ATOM   8995  C  CB    . ARG C 1 111 ? -40.133 -3.367  -47.900  1.00 49.92  ? 111 ARG C CB    1 
ATOM   8996  C  CG    . ARG C 1 111 ? -41.266 -4.297  -47.496  1.00 56.91  ? 111 ARG C CG    1 
ATOM   8997  C  CD    . ARG C 1 111 ? -40.858 -5.093  -46.276  1.00 64.43  ? 111 ARG C CD    1 
ATOM   8998  N  NE    . ARG C 1 111 ? -40.192 -6.322  -46.682  1.00 77.14  ? 111 ARG C NE    1 
ATOM   8999  C  CZ    . ARG C 1 111 ? -39.334 -7.013  -45.932  1.00 94.03  ? 111 ARG C CZ    1 
ATOM   9000  N  NH1   . ARG C 1 111 ? -38.961 -6.555  -44.748  1.00 95.33  ? 111 ARG C NH1   1 
ATOM   9001  N  NH2   . ARG C 1 111 ? -38.803 -8.135  -46.395  1.00 83.73  ? 111 ARG C NH2   1 
ATOM   9002  N  N     . ILE C 1 112 ? -40.045 -0.629  -49.860  1.00 40.38  ? 112 ILE C N     1 
ATOM   9003  C  CA    . ILE C 1 112 ? -39.567 0.724   -49.647  1.00 40.58  ? 112 ILE C CA    1 
ATOM   9004  C  C     . ILE C 1 112 ? -39.713 1.061   -48.165  1.00 43.71  ? 112 ILE C C     1 
ATOM   9005  O  O     . ILE C 1 112 ? -40.813 1.303   -47.694  1.00 46.44  ? 112 ILE C O     1 
ATOM   9006  C  CB    . ILE C 1 112 ? -40.344 1.682   -50.558  1.00 41.37  ? 112 ILE C CB    1 
ATOM   9007  C  CG1   . ILE C 1 112 ? -40.148 1.290   -52.026  1.00 42.61  ? 112 ILE C CG1   1 
ATOM   9008  C  CG2   . ILE C 1 112 ? -39.976 3.139   -50.288  1.00 42.89  ? 112 ILE C CG2   1 
ATOM   9009  C  CD1   . ILE C 1 112 ? -41.116 1.941   -52.988  1.00 46.31  ? 112 ILE C CD1   1 
ATOM   9010  N  N     . LEU C 1 113 ? -38.605 1.035   -47.411  1.00 40.90  ? 113 LEU C N     1 
ATOM   9011  C  CA    . LEU C 1 113 ? -38.668 1.136   -45.966  1.00 37.44  ? 113 LEU C CA    1 
ATOM   9012  C  C     . LEU C 1 113 ? -38.929 2.573   -45.533  1.00 40.55  ? 113 LEU C C     1 
ATOM   9013  O  O     . LEU C 1 113 ? -39.525 2.795   -44.480  1.00 41.16  ? 113 LEU C O     1 
ATOM   9014  C  CB    . LEU C 1 113 ? -37.386 0.580   -45.358  1.00 47.03  ? 113 LEU C CB    1 
ATOM   9015  C  CG    . LEU C 1 113 ? -37.117 -0.902  -45.627  1.00 52.23  ? 113 LEU C CG    1 
ATOM   9016  C  CD1   . LEU C 1 113 ? -35.688 -1.268  -45.265  1.00 49.03  ? 113 LEU C CD1   1 
ATOM   9017  C  CD2   . LEU C 1 113 ? -38.091 -1.778  -44.860  1.00 49.59  ? 113 LEU C CD2   1 
ATOM   9018  N  N     . GLU C 1 114 ? -38.488 3.555   -46.323  1.00 40.00  ? 114 GLU C N     1 
ATOM   9019  C  CA    . GLU C 1 114 ? -38.807 4.944   -46.017  1.00 40.88  ? 114 GLU C CA    1 
ATOM   9020  C  C     . GLU C 1 114 ? -38.449 5.810   -47.221  1.00 40.97  ? 114 GLU C C     1 
ATOM   9021  O  O     . GLU C 1 114 ? -37.488 5.512   -47.931  1.00 42.33  ? 114 GLU C O     1 
ATOM   9022  C  CB    . GLU C 1 114 ? -38.085 5.399   -44.747  1.00 45.17  ? 114 GLU C CB    1 
ATOM   9023  C  CG    . GLU C 1 114 ? -38.223 6.898   -44.522  1.00 51.31  ? 114 GLU C CG    1 
ATOM   9024  C  CD    . GLU C 1 114 ? -37.493 7.489   -43.331  1.00 56.11  ? 114 GLU C CD    1 
ATOM   9025  O  OE1   . GLU C 1 114 ? -36.697 6.762   -42.691  1.00 54.12  ? 114 GLU C OE1   1 
ATOM   9026  O  OE2   . GLU C 1 114 ? -37.741 8.687   -43.044  1.00 62.89  ? 114 GLU C OE2   1 
ATOM   9027  N  N     . VAL C 1 115 ? -39.286 6.809   -47.509  1.00 39.79  ? 115 VAL C N     1 
ATOM   9028  C  CA    . VAL C 1 115 ? -38.916 7.881   -48.413  1.00 44.48  ? 115 VAL C CA    1 
ATOM   9029  C  C     . VAL C 1 115 ? -39.143 9.174   -47.646  1.00 43.85  ? 115 VAL C C     1 
ATOM   9030  O  O     . VAL C 1 115 ? -40.198 9.375   -47.063  1.00 40.07  ? 115 VAL C O     1 
ATOM   9031  C  CB    . VAL C 1 115 ? -39.657 7.858   -49.758  1.00 47.57  ? 115 VAL C CB    1 
ATOM   9032  C  CG1   . VAL C 1 115 ? -39.196 8.983   -50.684  1.00 47.74  ? 115 VAL C CG1   1 
ATOM   9033  C  CG2   . VAL C 1 115 ? -39.494 6.509   -50.440  1.00 52.91  ? 115 VAL C CG2   1 
ATOM   9034  N  N     . ASN C 1 116 ? -38.105 9.999   -47.564  1.00 40.35  ? 116 ASN C N     1 
ATOM   9035  C  CA    . ASN C 1 116 ? -38.158 11.177  -46.722  1.00 36.02  ? 116 ASN C CA    1 
ATOM   9036  C  C     . ASN C 1 116 ? -37.983 12.380  -47.621  1.00 38.66  ? 116 ASN C C     1 
ATOM   9037  O  O     . ASN C 1 116 ? -36.954 12.538  -48.280  1.00 39.49  ? 116 ASN C O     1 
ATOM   9038  C  CB    . ASN C 1 116 ? -37.121 11.140  -45.604  1.00 39.91  ? 116 ASN C CB    1 
ATOM   9039  C  CG    . ASN C 1 116 ? -37.268 12.300  -44.641  1.00 38.15  ? 116 ASN C CG    1 
ATOM   9040  O  OD1   . ASN C 1 116 ? -37.253 13.474  -45.026  1.00 38.71  ? 116 ASN C OD1   1 
ATOM   9041  N  ND2   . ASN C 1 116 ? -37.415 11.974  -43.377  1.00 39.00  ? 116 ASN C ND2   1 
ATOM   9042  N  N     . GLU C 1 117 ? -39.002 13.231  -47.630  1.00 39.34  ? 117 GLU C N     1 
ATOM   9043  C  CA    . GLU C 1 117 ? -39.043 14.347  -48.551  1.00 43.70  ? 117 GLU C CA    1 
ATOM   9044  C  C     . GLU C 1 117 ? -38.151 15.474  -48.039  1.00 45.16  ? 117 GLU C C     1 
ATOM   9045  O  O     . GLU C 1 117 ? -37.352 16.019  -48.797  1.00 48.73  ? 117 GLU C O     1 
ATOM   9046  C  CB    . GLU C 1 117 ? -40.477 14.831  -48.728  1.00 41.61  ? 117 GLU C CB    1 
ATOM   9047  C  CG    . GLU C 1 117 ? -40.627 15.958  -49.737  1.00 46.38  ? 117 GLU C CG    1 
ATOM   9048  C  CD    . GLU C 1 117 ? -42.084 16.362  -49.893  1.00 42.90  ? 117 GLU C CD    1 
ATOM   9049  O  OE1   . GLU C 1 117 ? -42.791 16.423  -48.867  1.00 45.31  ? 117 GLU C OE1   1 
ATOM   9050  O  OE2   . GLU C 1 117 ? -42.483 16.624  -51.006  1.00 43.02  ? 117 GLU C OE2   1 
ATOM   9051  N  N     . GLU C 1 118 ? -38.308 15.828  -46.763  1.00 44.10  ? 118 GLU C N     1 
ATOM   9052  C  CA    . GLU C 1 118 ? -37.614 16.987  -46.220  1.00 46.22  ? 118 GLU C CA    1 
ATOM   9053  C  C     . GLU C 1 118 ? -36.097 16.736  -46.219  1.00 44.19  ? 118 GLU C C     1 
ATOM   9054  O  O     . GLU C 1 118 ? -35.336 17.677  -46.377  1.00 39.31  ? 118 GLU C O     1 
ATOM   9055  C  CB    . GLU C 1 118 ? -38.174 17.326  -44.833  1.00 49.82  ? 118 GLU C CB    1 
ATOM   9056  C  CG    . GLU C 1 118 ? -37.625 16.473  -43.704  1.00 55.83  ? 118 GLU C CG    1 
ATOM   9057  C  CD    . GLU C 1 118 ? -38.545 16.218  -42.521  1.00 65.97  ? 118 GLU C CD    1 
ATOM   9058  O  OE1   . GLU C 1 118 ? -38.400 16.898  -41.473  1.00 64.20  ? 118 GLU C OE1   1 
ATOM   9059  O  OE2   . GLU C 1 118 ? -39.367 15.289  -42.627  1.00 78.94  ? 118 GLU C OE2   1 
ATOM   9060  N  N     . PHE C 1 119 ? -35.646 15.480  -46.054  1.00 40.97  ? 119 PHE C N     1 
ATOM   9061  C  CA    . PHE C 1 119 ? -34.217 15.198  -46.080  1.00 41.54  ? 119 PHE C CA    1 
ATOM   9062  C  C     . PHE C 1 119 ? -33.744 14.562  -47.391  1.00 41.89  ? 119 PHE C C     1 
ATOM   9063  O  O     . PHE C 1 119 ? -32.555 14.254  -47.526  1.00 45.59  ? 119 PHE C O     1 
ATOM   9064  C  CB    . PHE C 1 119 ? -33.793 14.293  -44.927  1.00 38.34  ? 119 PHE C CB    1 
ATOM   9065  C  CG    . PHE C 1 119 ? -34.077 14.853  -43.563  1.00 43.24  ? 119 PHE C CG    1 
ATOM   9066  C  CD1   . PHE C 1 119 ? -33.642 16.118  -43.211  1.00 46.05  ? 119 PHE C CD1   1 
ATOM   9067  C  CD2   . PHE C 1 119 ? -34.785 14.109  -42.635  1.00 46.14  ? 119 PHE C CD2   1 
ATOM   9068  C  CE1   . PHE C 1 119 ? -33.892 16.613  -41.941  1.00 45.25  ? 119 PHE C CE1   1 
ATOM   9069  C  CE2   . PHE C 1 119 ? -35.077 14.627  -41.383  1.00 50.07  ? 119 PHE C CE2   1 
ATOM   9070  C  CZ    . PHE C 1 119 ? -34.639 15.879  -41.044  1.00 42.78  ? 119 PHE C CZ    1 
ATOM   9071  N  N     . GLY C 1 120 ? -34.656 14.362  -48.338  1.00 40.40  ? 120 GLY C N     1 
ATOM   9072  C  CA    . GLY C 1 120 ? -34.312 13.922  -49.679  1.00 36.43  ? 120 GLY C CA    1 
ATOM   9073  C  C     . GLY C 1 120 ? -33.660 12.543  -49.684  1.00 37.56  ? 120 GLY C C     1 
ATOM   9074  O  O     . GLY C 1 120 ? -32.512 12.402  -50.109  1.00 39.74  ? 120 GLY C O     1 
ATOM   9075  N  N     . TYR C 1 121 ? -34.346 11.514  -49.182  1.00 36.28  ? 121 TYR C N     1 
ATOM   9076  C  CA    . TYR C 1 121 ? -33.726 10.192  -49.238  1.00 39.76  ? 121 TYR C CA    1 
ATOM   9077  C  C     . TYR C 1 121 ? -34.740 9.063   -49.286  1.00 42.00  ? 121 TYR C C     1 
ATOM   9078  O  O     . TYR C 1 121 ? -35.931 9.275   -49.048  1.00 40.45  ? 121 TYR C O     1 
ATOM   9079  C  CB    . TYR C 1 121 ? -32.752 9.961   -48.082  1.00 40.43  ? 121 TYR C CB    1 
ATOM   9080  C  CG    . TYR C 1 121 ? -33.320 9.777   -46.693  1.00 41.62  ? 121 TYR C CG    1 
ATOM   9081  C  CD1   . TYR C 1 121 ? -33.867 8.566   -46.300  1.00 42.12  ? 121 TYR C CD1   1 
ATOM   9082  C  CD2   . TYR C 1 121 ? -33.221 10.781  -45.730  1.00 38.67  ? 121 TYR C CD2   1 
ATOM   9083  C  CE1   . TYR C 1 121 ? -34.367 8.377   -45.018  1.00 43.02  ? 121 TYR C CE1   1 
ATOM   9084  C  CE2   . TYR C 1 121 ? -33.681 10.599  -44.431  1.00 34.19  ? 121 TYR C CE2   1 
ATOM   9085  C  CZ    . TYR C 1 121 ? -34.270 9.389   -44.077  1.00 42.07  ? 121 TYR C CZ    1 
ATOM   9086  O  OH    . TYR C 1 121 ? -34.737 9.110   -42.810  1.00 40.26  ? 121 TYR C OH    1 
ATOM   9087  N  N     . ALA C 1 122 ? -34.219 7.870   -49.608  1.00 38.78  ? 122 ALA C N     1 
ATOM   9088  C  CA    . ALA C 1 122 ? -34.978 6.625   -49.507  1.00 40.46  ? 122 ALA C CA    1 
ATOM   9089  C  C     . ALA C 1 122 ? -34.141 5.566   -48.807  1.00 41.00  ? 122 ALA C C     1 
ATOM   9090  O  O     . ALA C 1 122 ? -32.917 5.562   -48.890  1.00 44.93  ? 122 ALA C O     1 
ATOM   9091  C  CB    . ALA C 1 122 ? -35.392 6.136   -50.880  1.00 38.18  ? 122 ALA C CB    1 
ATOM   9092  N  N     . LEU C 1 123 ? -34.817 4.651   -48.130  1.00 40.19  ? 123 LEU C N     1 
ATOM   9093  C  CA    . LEU C 1 123 ? -34.204 3.425   -47.653  1.00 35.90  ? 123 LEU C CA    1 
ATOM   9094  C  C     . LEU C 1 123 ? -34.968 2.288   -48.310  1.00 38.87  ? 123 LEU C C     1 
ATOM   9095  O  O     . LEU C 1 123 ? -36.187 2.188   -48.144  1.00 44.22  ? 123 LEU C O     1 
ATOM   9096  C  CB    . LEU C 1 123 ? -34.295 3.344   -46.125  1.00 39.01  ? 123 LEU C CB    1 
ATOM   9097  C  CG    . LEU C 1 123 ? -33.758 2.079   -45.457  1.00 34.38  ? 123 LEU C CG    1 
ATOM   9098  C  CD1   . LEU C 1 123 ? -32.259 1.957   -45.647  1.00 37.90  ? 123 LEU C CD1   1 
ATOM   9099  C  CD2   . LEU C 1 123 ? -34.095 2.082   -43.970  1.00 36.58  ? 123 LEU C CD2   1 
ATOM   9100  N  N     . VAL C 1 124 ? -34.251 1.460   -49.066  1.00 34.88  ? 124 VAL C N     1 
ATOM   9101  C  CA    . VAL C 1 124 ? -34.914 0.480   -49.902  1.00 39.88  ? 124 VAL C CA    1 
ATOM   9102  C  C     . VAL C 1 124 ? -34.271 -0.881  -49.677  1.00 40.47  ? 124 VAL C C     1 
ATOM   9103  O  O     . VAL C 1 124 ? -33.106 -0.982  -49.298  1.00 45.05  ? 124 VAL C O     1 
ATOM   9104  C  CB    . VAL C 1 124 ? -34.884 0.878   -51.387  1.00 38.32  ? 124 VAL C CB    1 
ATOM   9105  C  CG1   . VAL C 1 124 ? -35.816 2.031   -51.678  1.00 39.44  ? 124 VAL C CG1   1 
ATOM   9106  C  CG2   . VAL C 1 124 ? -33.451 1.178   -51.857  1.00 39.53  ? 124 VAL C CG2   1 
ATOM   9107  N  N     . GLU C 1 125 ? -35.076 -1.914  -49.915  1.00 37.70  ? 125 GLU C N     1 
ATOM   9108  C  CA    . GLU C 1 125 ? -34.602 -3.278  -50.008  1.00 38.26  ? 125 GLU C CA    1 
ATOM   9109  C  C     . GLU C 1 125 ? -34.226 -3.575  -51.458  1.00 40.68  ? 125 GLU C C     1 
ATOM   9110  O  O     . GLU C 1 125 ? -34.614 -2.864  -52.389  1.00 42.34  ? 125 GLU C O     1 
ATOM   9111  C  CB    . GLU C 1 125 ? -35.679 -4.234  -49.512  1.00 42.78  ? 125 GLU C CB    1 
ATOM   9112  C  CG    . GLU C 1 125 ? -35.956 -4.103  -48.025  1.00 47.57  ? 125 GLU C CG    1 
ATOM   9113  C  CD    . GLU C 1 125 ? -36.810 -5.224  -47.458  1.00 49.45  ? 125 GLU C CD    1 
ATOM   9114  O  OE1   . GLU C 1 125 ? -37.688 -5.706  -48.201  1.00 48.81  ? 125 GLU C OE1   1 
ATOM   9115  O  OE2   . GLU C 1 125 ? -36.614 -5.590  -46.275  1.00 54.40  ? 125 GLU C OE2   1 
ATOM   9116  N  N     . PRO C 1 126 ? -33.439 -4.645  -51.690  1.00 37.30  ? 126 PRO C N     1 
ATOM   9117  C  CA    . PRO C 1 126 ? -32.852 -4.917  -53.003  1.00 42.01  ? 126 PRO C CA    1 
ATOM   9118  C  C     . PRO C 1 126 ? -33.853 -5.177  -54.125  1.00 39.73  ? 126 PRO C C     1 
ATOM   9119  O  O     . PRO C 1 126 ? -33.522 -4.982  -55.292  1.00 41.43  ? 126 PRO C O     1 
ATOM   9120  C  CB    . PRO C 1 126 ? -32.016 -6.179  -52.749  1.00 39.48  ? 126 PRO C CB    1 
ATOM   9121  C  CG    . PRO C 1 126 ? -31.738 -6.129  -51.275  1.00 39.13  ? 126 PRO C CG    1 
ATOM   9122  C  CD    . PRO C 1 126 ? -33.024 -5.610  -50.680  1.00 37.55  ? 126 PRO C CD    1 
ATOM   9123  N  N     . GLY C 1 127 ? -35.062 -5.628  -53.768  1.00 45.61  ? 127 GLY C N     1 
ATOM   9124  C  CA    . GLY C 1 127 ? -36.108 -5.945  -54.737  1.00 45.52  ? 127 GLY C CA    1 
ATOM   9125  C  C     . GLY C 1 127 ? -36.785 -4.709  -55.319  1.00 47.34  ? 127 GLY C C     1 
ATOM   9126  O  O     . GLY C 1 127 ? -37.526 -4.787  -56.297  1.00 51.66  ? 127 GLY C O     1 
ATOM   9127  N  N     . VAL C 1 128 ? -36.522 -3.542  -54.740  1.00 47.86  ? 128 VAL C N     1 
ATOM   9128  C  CA    . VAL C 1 128 ? -37.199 -2.347  -55.198  1.00 44.57  ? 128 VAL C CA    1 
ATOM   9129  C  C     . VAL C 1 128 ? -36.628 -1.938  -56.545  1.00 45.90  ? 128 VAL C C     1 
ATOM   9130  O  O     . VAL C 1 128 ? -35.416 -1.816  -56.711  1.00 45.44  ? 128 VAL C O     1 
ATOM   9131  C  CB    . VAL C 1 128 ? -37.106 -1.205  -54.174  1.00 45.40  ? 128 VAL C CB    1 
ATOM   9132  C  CG1   . VAL C 1 128 ? -37.567 0.106   -54.770  1.00 42.24  ? 128 VAL C CG1   1 
ATOM   9133  C  CG2   . VAL C 1 128 ? -37.874 -1.528  -52.898  1.00 46.68  ? 128 VAL C CG2   1 
ATOM   9134  N  N     . SER C 1 129 ? -37.540 -1.703  -57.499  1.00 43.51  ? 129 SER C N     1 
ATOM   9135  C  CA    . SER C 1 129 ? -37.158 -1.379  -58.858  1.00 45.21  ? 129 SER C CA    1 
ATOM   9136  C  C     . SER C 1 129 ? -37.262 0.133   -59.014  1.00 42.05  ? 129 SER C C     1 
ATOM   9137  O  O     . SER C 1 129 ? -37.914 0.777   -58.207  1.00 40.71  ? 129 SER C O     1 
ATOM   9138  C  CB    . SER C 1 129 ? -38.042 -2.107  -59.846  1.00 46.60  ? 129 SER C CB    1 
ATOM   9139  O  OG    . SER C 1 129 ? -39.237 -1.374  -60.097  1.00 48.76  ? 129 SER C OG    1 
ATOM   9140  N  N     . TYR C 1 130 ? -36.686 0.689   -60.078  1.00 42.78  ? 130 TYR C N     1 
ATOM   9141  C  CA    . TYR C 1 130 ? -36.858 2.108   -60.321  1.00 42.71  ? 130 TYR C CA    1 
ATOM   9142  C  C     . TYR C 1 130 ? -38.319 2.450   -60.606  1.00 45.94  ? 130 TYR C C     1 
ATOM   9143  O  O     . TYR C 1 130 ? -38.782 3.537   -60.235  1.00 43.96  ? 130 TYR C O     1 
ATOM   9144  C  CB    . TYR C 1 130 ? -35.944 2.570   -61.443  1.00 42.56  ? 130 TYR C CB    1 
ATOM   9145  C  CG    . TYR C 1 130 ? -34.475 2.455   -61.132  1.00 48.27  ? 130 TYR C CG    1 
ATOM   9146  C  CD1   . TYR C 1 130 ? -33.820 3.410   -60.374  1.00 47.39  ? 130 TYR C CD1   1 
ATOM   9147  C  CD2   . TYR C 1 130 ? -33.731 1.387   -61.605  1.00 54.44  ? 130 TYR C CD2   1 
ATOM   9148  C  CE1   . TYR C 1 130 ? -32.461 3.320   -60.106  1.00 45.22  ? 130 TYR C CE1   1 
ATOM   9149  C  CE2   . TYR C 1 130 ? -32.373 1.283   -61.354  1.00 49.66  ? 130 TYR C CE2   1 
ATOM   9150  C  CZ    . TYR C 1 130 ? -31.734 2.248   -60.592  1.00 48.78  ? 130 TYR C CZ    1 
ATOM   9151  O  OH    . TYR C 1 130 ? -30.370 2.135   -60.366  1.00 45.27  ? 130 TYR C OH    1 
ATOM   9152  N  N     . PHE C 1 131 ? -39.027 1.557   -61.305  1.00 43.16  ? 131 PHE C N     1 
ATOM   9153  C  CA    . PHE C 1 131 ? -40.451 1.743   -61.533  1.00 45.95  ? 131 PHE C CA    1 
ATOM   9154  C  C     . PHE C 1 131 ? -41.165 1.859   -60.187  1.00 42.86  ? 131 PHE C C     1 
ATOM   9155  O  O     . PHE C 1 131 ? -41.947 2.773   -59.973  1.00 51.95  ? 131 PHE C O     1 
ATOM   9156  C  CB    . PHE C 1 131 ? -41.027 0.615   -62.402  1.00 46.38  ? 131 PHE C CB    1 
ATOM   9157  C  CG    . PHE C 1 131 ? -40.753 0.779   -63.871  1.00 43.16  ? 131 PHE C CG    1 
ATOM   9158  C  CD1   . PHE C 1 131 ? -41.221 1.892   -64.549  1.00 48.95  ? 131 PHE C CD1   1 
ATOM   9159  C  CD2   . PHE C 1 131 ? -40.009 -0.152  -64.567  1.00 48.25  ? 131 PHE C CD2   1 
ATOM   9160  C  CE1   . PHE C 1 131 ? -40.940 2.078   -65.891  1.00 50.29  ? 131 PHE C CE1   1 
ATOM   9161  C  CE2   . PHE C 1 131 ? -39.743 0.028   -65.918  1.00 46.64  ? 131 PHE C CE2   1 
ATOM   9162  C  CZ    . PHE C 1 131 ? -40.201 1.143   -66.573  1.00 47.63  ? 131 PHE C CZ    1 
ATOM   9163  N  N     . GLU C 1 132 ? -40.862 0.949   -59.262  1.00 47.74  ? 132 GLU C N     1 
ATOM   9164  C  CA    . GLU C 1 132 ? -41.580 0.908   -57.998  1.00 47.74  ? 132 GLU C CA    1 
ATOM   9165  C  C     . GLU C 1 132 ? -41.348 2.208   -57.214  1.00 51.25  ? 132 GLU C C     1 
ATOM   9166  O  O     . GLU C 1 132 ? -42.300 2.834   -56.755  1.00 45.96  ? 132 GLU C O     1 
ATOM   9167  C  CB    . GLU C 1 132 ? -41.183 -0.379  -57.281  1.00 47.33  ? 132 GLU C CB    1 
ATOM   9168  C  CG    . GLU C 1 132 ? -41.735 -1.607  -57.990  1.00 53.39  ? 132 GLU C CG    1 
ATOM   9169  C  CD    . GLU C 1 132 ? -41.179 -2.948  -57.558  1.00 59.20  ? 132 GLU C CD    1 
ATOM   9170  O  OE1   . GLU C 1 132 ? -40.247 -2.981  -56.746  1.00 72.16  ? 132 GLU C OE1   1 
ATOM   9171  O  OE2   . GLU C 1 132 ? -41.680 -3.961  -58.047  1.00 78.61  ? 132 GLU C OE2   1 
ATOM   9172  N  N     . LEU C 1 133 ? -40.092 2.666   -57.112  1.00 44.66  ? 133 LEU C N     1 
ATOM   9173  C  CA    . LEU C 1 133 ? -39.772 3.781   -56.227  1.00 42.59  ? 133 LEU C CA    1 
ATOM   9174  C  C     . LEU C 1 133 ? -40.334 5.064   -56.824  1.00 40.70  ? 133 LEU C C     1 
ATOM   9175  O  O     . LEU C 1 133 ? -40.896 5.895   -56.112  1.00 44.01  ? 133 LEU C O     1 
ATOM   9176  C  CB    . LEU C 1 133 ? -38.245 3.859   -56.013  1.00 44.06  ? 133 LEU C CB    1 
ATOM   9177  C  CG    . LEU C 1 133 ? -37.735 5.019   -55.150  1.00 40.49  ? 133 LEU C CG    1 
ATOM   9178  C  CD1   . LEU C 1 133 ? -38.260 4.916   -53.722  1.00 41.88  ? 133 LEU C CD1   1 
ATOM   9179  C  CD2   . LEU C 1 133 ? -36.207 5.048   -55.116  1.00 42.16  ? 133 LEU C CD2   1 
ATOM   9180  N  N     . TYR C 1 134 ? -40.203 5.200   -58.142  1.00 40.43  ? 134 TYR C N     1 
ATOM   9181  C  CA    . TYR C 1 134 ? -40.850 6.293   -58.843  1.00 46.20  ? 134 TYR C CA    1 
ATOM   9182  C  C     . TYR C 1 134 ? -42.341 6.393   -58.502  1.00 49.17  ? 134 TYR C C     1 
ATOM   9183  O  O     . TYR C 1 134 ? -42.852 7.511   -58.317  1.00 44.19  ? 134 TYR C O     1 
ATOM   9184  C  CB    . TYR C 1 134 ? -40.718 6.122   -60.352  1.00 41.46  ? 134 TYR C CB    1 
ATOM   9185  C  CG    . TYR C 1 134 ? -41.278 7.276   -61.147  1.00 43.88  ? 134 TYR C CG    1 
ATOM   9186  C  CD1   . TYR C 1 134 ? -40.630 8.490   -61.181  1.00 38.31  ? 134 TYR C CD1   1 
ATOM   9187  C  CD2   . TYR C 1 134 ? -42.482 7.171   -61.825  1.00 45.74  ? 134 TYR C CD2   1 
ATOM   9188  C  CE1   . TYR C 1 134 ? -41.113 9.556   -61.908  1.00 45.09  ? 134 TYR C CE1   1 
ATOM   9189  C  CE2   . TYR C 1 134 ? -42.983 8.226   -62.568  1.00 39.68  ? 134 TYR C CE2   1 
ATOM   9190  C  CZ    . TYR C 1 134 ? -42.295 9.421   -62.619  1.00 47.59  ? 134 TYR C CZ    1 
ATOM   9191  O  OH    . TYR C 1 134 ? -42.776 10.483  -63.336  1.00 42.35  ? 134 TYR C OH    1 
ATOM   9192  N  N     . ASP C 1 135 ? -43.035 5.240   -58.519  1.00 49.74  ? 135 ASP C N     1 
ATOM   9193  C  CA    . ASP C 1 135 ? -44.489 5.197   -58.369  1.00 52.79  ? 135 ASP C CA    1 
ATOM   9194  C  C     . ASP C 1 135 ? -44.895 5.464   -56.922  1.00 47.45  ? 135 ASP C C     1 
ATOM   9195  O  O     . ASP C 1 135 ? -45.936 6.060   -56.681  1.00 52.82  ? 135 ASP C O     1 
ATOM   9196  C  CB    . ASP C 1 135 ? -45.066 3.847   -58.804  1.00 53.81  ? 135 ASP C CB    1 
ATOM   9197  C  CG    . ASP C 1 135 ? -45.033 3.623   -60.307  1.00 52.01  ? 135 ASP C CG    1 
ATOM   9198  O  OD1   . ASP C 1 135 ? -44.894 4.608   -61.053  1.00 56.33  ? 135 ASP C OD1   1 
ATOM   9199  O  OD2   . ASP C 1 135 ? -45.125 2.468   -60.716  1.00 50.28  ? 135 ASP C OD2   1 
ATOM   9200  N  N     . TYR C 1 136 ? -44.091 4.962   -55.974  1.00 46.58  ? 136 TYR C N     1 
ATOM   9201  C  CA    . TYR C 1 136 ? -44.223 5.276   -54.558  1.00 47.03  ? 136 TYR C CA    1 
ATOM   9202  C  C     . TYR C 1 136 ? -44.182 6.788   -54.344  1.00 54.36  ? 136 TYR C C     1 
ATOM   9203  O  O     . TYR C 1 136 ? -45.042 7.322   -53.651  1.00 52.56  ? 136 TYR C O     1 
ATOM   9204  C  CB    . TYR C 1 136 ? -43.108 4.615   -53.753  1.00 47.15  ? 136 TYR C CB    1 
ATOM   9205  C  CG    . TYR C 1 136 ? -43.316 4.666   -52.266  1.00 53.32  ? 136 TYR C CG    1 
ATOM   9206  C  CD1   . TYR C 1 136 ? -44.007 3.664   -51.605  1.00 52.74  ? 136 TYR C CD1   1 
ATOM   9207  C  CD2   . TYR C 1 136 ? -42.859 5.739   -51.528  1.00 48.19  ? 136 TYR C CD2   1 
ATOM   9208  C  CE1   . TYR C 1 136 ? -44.206 3.706   -50.238  1.00 53.39  ? 136 TYR C CE1   1 
ATOM   9209  C  CE2   . TYR C 1 136 ? -43.067 5.808   -50.164  1.00 51.78  ? 136 TYR C CE2   1 
ATOM   9210  C  CZ    . TYR C 1 136 ? -43.734 4.787   -49.520  1.00 55.97  ? 136 TYR C CZ    1 
ATOM   9211  O  OH    . TYR C 1 136 ? -43.958 4.886   -48.185  1.00 60.06  ? 136 TYR C OH    1 
ATOM   9212  N  N     . ILE C 1 137 ? -43.194 7.459   -54.961  1.00 49.86  ? 137 ILE C N     1 
ATOM   9213  C  CA    . ILE C 1 137 ? -42.949 8.882   -54.776  1.00 45.97  ? 137 ILE C CA    1 
ATOM   9214  C  C     . ILE C 1 137 ? -44.123 9.677   -55.338  1.00 48.86  ? 137 ILE C C     1 
ATOM   9215  O  O     . ILE C 1 137 ? -44.600 10.634  -54.713  1.00 52.77  ? 137 ILE C O     1 
ATOM   9216  C  CB    . ILE C 1 137 ? -41.591 9.290   -55.404  1.00 42.93  ? 137 ILE C CB    1 
ATOM   9217  C  CG1   . ILE C 1 137 ? -40.426 8.853   -54.516  1.00 44.85  ? 137 ILE C CG1   1 
ATOM   9218  C  CG2   . ILE C 1 137 ? -41.535 10.783  -55.724  1.00 42.97  ? 137 ILE C CG2   1 
ATOM   9219  C  CD1   . ILE C 1 137 ? -39.053 8.909   -55.171  1.00 46.56  ? 137 ILE C CD1   1 
ATOM   9220  N  N     . GLN C 1 138 ? -44.552 9.324   -56.555  1.00 57.34  ? 138 GLN C N     1 
ATOM   9221  C  CA    . GLN C 1 138 ? -45.620 10.063  -57.208  1.00 53.77  ? 138 GLN C CA    1 
ATOM   9222  C  C     . GLN C 1 138 ? -46.935 9.818   -56.481  1.00 62.00  ? 138 GLN C C     1 
ATOM   9223  O  O     . GLN C 1 138 ? -47.749 10.732  -56.366  1.00 79.44  ? 138 GLN C O     1 
ATOM   9224  C  CB    . GLN C 1 138 ? -45.727 9.701   -58.676  1.00 52.81  ? 138 GLN C CB    1 
ATOM   9225  C  CG    . GLN C 1 138 ? -44.479 10.074  -59.449  1.00 60.50  ? 138 GLN C CG    1 
ATOM   9226  C  CD    . GLN C 1 138 ? -44.032 11.491  -59.207  1.00 63.77  ? 138 GLN C CD    1 
ATOM   9227  O  OE1   . GLN C 1 138 ? -44.808 12.356  -58.804  1.00 74.85  ? 138 GLN C OE1   1 
ATOM   9228  N  NE2   . GLN C 1 138 ? -42.764 11.735  -59.482  1.00 68.27  ? 138 GLN C NE2   1 
ATOM   9229  N  N     . GLU C 1 139 ? -47.088 8.619   -55.923  1.00 54.57  ? 139 GLU C N     1 
ATOM   9230  C  CA    . GLU C 1 139 ? -48.306 8.285   -55.216  1.00 68.68  ? 139 GLU C CA    1 
ATOM   9231  C  C     . GLU C 1 139 ? -48.376 9.122   -53.938  1.00 74.00  ? 139 GLU C C     1 
ATOM   9232  O  O     . GLU C 1 139 ? -49.375 9.803   -53.726  1.00 80.07  ? 139 GLU C O     1 
ATOM   9233  C  CB    . GLU C 1 139 ? -48.396 6.762   -55.073  1.00 73.04  ? 139 GLU C CB    1 
ATOM   9234  C  CG    . GLU C 1 139 ? -48.646 6.101   -56.436  1.00 82.11  ? 139 GLU C CG    1 
ATOM   9235  C  CD    . GLU C 1 139 ? -48.670 4.581   -56.490  1.00 83.56  ? 139 GLU C CD    1 
ATOM   9236  O  OE1   . GLU C 1 139 ? -48.579 4.028   -57.622  1.00 70.90  ? 139 GLU C OE1   1 
ATOM   9237  O  OE2   . GLU C 1 139 ? -48.814 3.955   -55.413  1.00 83.56  ? 139 GLU C OE2   1 
ATOM   9238  N  N     . LYS C 1 140 ? -47.292 9.156   -53.147  1.00 65.31  ? 140 LYS C N     1 
ATOM   9239  C  CA    . LYS C 1 140 ? -47.275 9.900   -51.892  1.00 58.22  ? 140 LYS C CA    1 
ATOM   9240  C  C     . LYS C 1 140 ? -47.253 11.411  -52.117  1.00 55.60  ? 140 LYS C C     1 
ATOM   9241  O  O     . LYS C 1 140 ? -47.284 12.169  -51.149  1.00 69.85  ? 140 LYS C O     1 
ATOM   9242  C  CB    . LYS C 1 140 ? -46.070 9.527   -51.022  1.00 62.10  ? 140 LYS C CB    1 
ATOM   9243  C  CG    . LYS C 1 140 ? -46.100 8.144   -50.383  1.00 63.74  ? 140 LYS C CG    1 
ATOM   9244  C  CD    . LYS C 1 140 ? -47.314 7.861   -49.526  1.00 64.47  ? 140 LYS C CD    1 
ATOM   9245  C  CE    . LYS C 1 140 ? -47.168 6.545   -48.792  1.00 67.17  ? 140 LYS C CE    1 
ATOM   9246  N  NZ    . LYS C 1 140 ? -48.437 6.112   -48.167  1.00 71.72  ? 140 LYS C NZ    1 
ATOM   9247  N  N     . GLY C 1 141 ? -47.169 11.848  -53.374  1.00 51.88  ? 141 GLY C N     1 
ATOM   9248  C  CA    . GLY C 1 141 ? -47.041 13.253  -53.721  1.00 57.07  ? 141 GLY C CA    1 
ATOM   9249  C  C     . GLY C 1 141 ? -45.708 13.910  -53.339  1.00 56.33  ? 141 GLY C C     1 
ATOM   9250  O  O     . GLY C 1 141 ? -45.665 15.123  -53.194  1.00 60.11  ? 141 GLY C O     1 
ATOM   9251  N  N     . LEU C 1 142 ? -44.600 13.165  -53.274  1.00 57.94  ? 142 LEU C N     1 
ATOM   9252  C  CA    . LEU C 1 142 ? -43.353 13.733  -52.758  1.00 56.06  ? 142 LEU C CA    1 
ATOM   9253  C  C     . LEU C 1 142 ? -42.601 14.530  -53.828  1.00 51.15  ? 142 LEU C C     1 
ATOM   9254  O  O     . LEU C 1 142 ? -42.564 14.153  -54.995  1.00 51.88  ? 142 LEU C O     1 
ATOM   9255  C  CB    . LEU C 1 142 ? -42.504 12.594  -52.197  1.00 54.94  ? 142 LEU C CB    1 
ATOM   9256  C  CG    . LEU C 1 142 ? -43.197 11.732  -51.145  1.00 54.19  ? 142 LEU C CG    1 
ATOM   9257  C  CD1   . LEU C 1 142 ? -42.211 10.765  -50.512  1.00 53.62  ? 142 LEU C CD1   1 
ATOM   9258  C  CD2   . LEU C 1 142 ? -43.862 12.579  -50.074  1.00 55.31  ? 142 LEU C CD2   1 
ATOM   9259  N  N     . LYS C 1 143 ? -42.008 15.665  -53.436  1.00 53.65  ? 143 LYS C N     1 
ATOM   9260  C  CA    . LYS C 1 143 ? -41.342 16.550  -54.385  1.00 52.02  ? 143 LYS C CA    1 
ATOM   9261  C  C     . LYS C 1 143 ? -39.882 16.135  -54.565  1.00 45.45  ? 143 LYS C C     1 
ATOM   9262  O  O     . LYS C 1 143 ? -38.977 16.933  -54.324  1.00 43.40  ? 143 LYS C O     1 
ATOM   9263  C  CB    . LYS C 1 143 ? -41.414 18.003  -53.912  1.00 57.77  ? 143 LYS C CB    1 
ATOM   9264  C  CG    . LYS C 1 143 ? -42.799 18.624  -53.896  1.00 65.96  ? 143 LYS C CG    1 
ATOM   9265  C  CD    . LYS C 1 143 ? -43.540 18.487  -55.201  1.00 81.34  ? 143 LYS C CD    1 
ATOM   9266  C  CE    . LYS C 1 143 ? -44.770 19.367  -55.249  1.00 89.93  ? 143 LYS C CE    1 
ATOM   9267  N  NZ    . LYS C 1 143 ? -45.633 19.018  -56.397  1.00 86.05  ? 143 LYS C NZ    1 
ATOM   9268  N  N     . LEU C 1 144 ? -39.677 14.890  -55.013  1.00 42.81  ? 144 LEU C N     1 
ATOM   9269  C  CA    . LEU C 1 144 ? -38.355 14.308  -55.193  1.00 44.95  ? 144 LEU C CA    1 
ATOM   9270  C  C     . LEU C 1 144 ? -38.265 13.705  -56.588  1.00 45.88  ? 144 LEU C C     1 
ATOM   9271  O  O     . LEU C 1 144 ? -39.263 13.210  -57.098  1.00 43.06  ? 144 LEU C O     1 
ATOM   9272  C  CB    . LEU C 1 144 ? -38.136 13.183  -54.179  1.00 40.40  ? 144 LEU C CB    1 
ATOM   9273  C  CG    . LEU C 1 144 ? -38.214 13.581  -52.713  1.00 45.75  ? 144 LEU C CG    1 
ATOM   9274  C  CD1   . LEU C 1 144 ? -38.023 12.363  -51.835  1.00 44.90  ? 144 LEU C CD1   1 
ATOM   9275  C  CD2   . LEU C 1 144 ? -37.188 14.664  -52.382  1.00 42.81  ? 144 LEU C CD2   1 
ATOM   9276  N  N     . TRP C 1 145 ? -37.052 13.703  -57.154  1.00 43.49  ? 145 TRP C N     1 
ATOM   9277  C  CA    . TRP C 1 145 ? -36.727 12.952  -58.359  1.00 42.48  ? 145 TRP C CA    1 
ATOM   9278  C  C     . TRP C 1 145 ? -35.789 11.804  -58.017  1.00 42.13  ? 145 TRP C C     1 
ATOM   9279  O  O     . TRP C 1 145 ? -34.970 11.894  -57.106  1.00 44.99  ? 145 TRP C O     1 
ATOM   9280  C  CB    . TRP C 1 145 ? -36.087 13.859  -59.416  1.00 46.09  ? 145 TRP C CB    1 
ATOM   9281  C  CG    . TRP C 1 145 ? -37.041 14.830  -60.031  1.00 47.99  ? 145 TRP C CG    1 
ATOM   9282  C  CD1   . TRP C 1 145 ? -38.348 15.025  -59.692  1.00 46.92  ? 145 TRP C CD1   1 
ATOM   9283  C  CD2   . TRP C 1 145 ? -36.766 15.735  -61.110  1.00 47.49  ? 145 TRP C CD2   1 
ATOM   9284  N  NE1   . TRP C 1 145 ? -38.893 16.008  -60.467  1.00 49.28  ? 145 TRP C NE1   1 
ATOM   9285  C  CE2   . TRP C 1 145 ? -37.947 16.469  -61.339  1.00 50.07  ? 145 TRP C CE2   1 
ATOM   9286  C  CE3   . TRP C 1 145 ? -35.630 16.033  -61.869  1.00 50.47  ? 145 TRP C CE3   1 
ATOM   9287  C  CZ2   . TRP C 1 145 ? -38.033 17.460  -62.318  1.00 51.50  ? 145 TRP C CZ2   1 
ATOM   9288  C  CZ3   . TRP C 1 145 ? -35.712 17.009  -62.834  1.00 50.64  ? 145 TRP C CZ3   1 
ATOM   9289  C  CH2   . TRP C 1 145 ? -36.907 17.695  -63.070  1.00 50.24  ? 145 TRP C CH2   1 
ATOM   9290  N  N     . ILE C 1 146 ? -35.934 10.702  -58.742  1.00 44.50  ? 146 ILE C N     1 
ATOM   9291  C  CA    . ILE C 1 146 ? -35.008 9.597   -58.619  1.00 41.95  ? 146 ILE C CA    1 
ATOM   9292  C  C     . ILE C 1 146 ? -34.026 9.733   -59.780  1.00 38.66  ? 146 ILE C C     1 
ATOM   9293  O  O     . ILE C 1 146 ? -34.132 10.662  -60.560  1.00 41.63  ? 146 ILE C O     1 
ATOM   9294  C  CB    . ILE C 1 146 ? -35.733 8.240   -58.601  1.00 44.26  ? 146 ILE C CB    1 
ATOM   9295  C  CG1   . ILE C 1 146 ? -36.466 7.940   -59.913  1.00 48.17  ? 146 ILE C CG1   1 
ATOM   9296  C  CG2   . ILE C 1 146 ? -36.665 8.166   -57.420  1.00 48.40  ? 146 ILE C CG2   1 
ATOM   9297  C  CD1   . ILE C 1 146 ? -36.941 6.487   -60.018  1.00 47.65  ? 146 ILE C CD1   1 
ATOM   9298  N  N     . ASP C 1 147 ? -33.053 8.830   -59.859  1.00 39.74  ? 147 ASP C N     1 
ATOM   9299  C  CA    . ASP C 1 147 ? -32.112 8.870   -60.963  1.00 39.60  ? 147 ASP C CA    1 
ATOM   9300  C  C     . ASP C 1 147 ? -32.023 7.470   -61.570  1.00 36.46  ? 147 ASP C C     1 
ATOM   9301  O  O     . ASP C 1 147 ? -31.669 6.484   -60.904  1.00 35.88  ? 147 ASP C O     1 
ATOM   9302  C  CB    . ASP C 1 147 ? -30.767 9.419   -60.507  1.00 41.54  ? 147 ASP C CB    1 
ATOM   9303  C  CG    . ASP C 1 147 ? -29.757 9.429   -61.642  1.00 38.98  ? 147 ASP C CG    1 
ATOM   9304  O  OD1   . ASP C 1 147 ? -29.397 8.329   -62.095  1.00 33.54  ? 147 ASP C OD1   1 
ATOM   9305  O  OD2   . ASP C 1 147 ? -29.423 10.527  -62.103  1.00 37.71  ? 147 ASP C OD2   1 
ATOM   9306  N  N     . VAL C 1 148 ? -32.355 7.398   -62.856  1.00 35.26  ? 148 VAL C N     1 
ATOM   9307  C  CA    . VAL C 1 148 ? -32.620 6.114   -63.474  1.00 41.27  ? 148 VAL C CA    1 
ATOM   9308  C  C     . VAL C 1 148 ? -31.575 5.817   -64.526  1.00 37.48  ? 148 VAL C C     1 
ATOM   9309  O  O     . VAL C 1 148 ? -31.152 6.708   -65.246  1.00 36.48  ? 148 VAL C O     1 
ATOM   9310  C  CB    . VAL C 1 148 ? -34.029 6.043   -64.078  1.00 44.15  ? 148 VAL C CB    1 
ATOM   9311  C  CG1   . VAL C 1 148 ? -35.070 6.314   -62.998  1.00 47.40  ? 148 VAL C CG1   1 
ATOM   9312  C  CG2   . VAL C 1 148 ? -34.193 6.977   -65.266  1.00 46.12  ? 148 VAL C CG2   1 
ATOM   9313  N  N     . PRO C 1 149 ? -31.160 4.539   -64.601  1.00 37.07  ? 149 PRO C N     1 
ATOM   9314  C  CA    . PRO C 1 149 ? -30.438 4.020   -65.750  1.00 45.66  ? 149 PRO C CA    1 
ATOM   9315  C  C     . PRO C 1 149 ? -31.471 3.823   -66.860  1.00 50.41  ? 149 PRO C C     1 
ATOM   9316  O  O     . PRO C 1 149 ? -32.676 3.889   -66.605  1.00 55.13  ? 149 PRO C O     1 
ATOM   9317  C  CB    . PRO C 1 149 ? -29.852 2.720   -65.180  1.00 41.15  ? 149 PRO C CB    1 
ATOM   9318  C  CG    . PRO C 1 149 ? -30.945 2.220   -64.263  1.00 38.64  ? 149 PRO C CG    1 
ATOM   9319  C  CD    . PRO C 1 149 ? -31.467 3.488   -63.622  1.00 37.06  ? 149 PRO C CD    1 
ATOM   9320  N  N     . ASP C 1 150 ? -30.994 3.608   -68.087  1.00 51.26  ? 150 ASP C N     1 
ATOM   9321  C  CA    . ASP C 1 150 ? -31.877 3.357   -69.214  1.00 50.60  ? 150 ASP C CA    1 
ATOM   9322  C  C     . ASP C 1 150 ? -32.735 2.121   -68.936  1.00 51.48  ? 150 ASP C C     1 
ATOM   9323  O  O     . ASP C 1 150 ? -33.895 2.090   -69.324  1.00 51.15  ? 150 ASP C O     1 
ATOM   9324  C  CB    . ASP C 1 150 ? -31.075 3.188   -70.497  1.00 53.74  ? 150 ASP C CB    1 
ATOM   9325  C  CG    . ASP C 1 150 ? -30.245 4.406   -70.865  1.00 56.97  ? 150 ASP C CG    1 
ATOM   9326  O  OD1   . ASP C 1 150 ? -30.829 5.501   -70.986  1.00 58.10  ? 150 ASP C OD1   1 
ATOM   9327  O  OD2   . ASP C 1 150 ? -29.012 4.249   -70.998  1.00 63.67  ? 150 ASP C OD2   1 
ATOM   9328  N  N     . ASN C 1 151 ? -32.184 1.135   -68.207  1.00 49.26  ? 151 ASN C N     1 
ATOM   9329  C  CA    . ASN C 1 151 ? -32.951 -0.036  -67.812  1.00 51.75  ? 151 ASN C CA    1 
ATOM   9330  C  C     . ASN C 1 151 ? -33.807 0.261   -66.582  1.00 50.45  ? 151 ASN C C     1 
ATOM   9331  O  O     . ASN C 1 151 ? -33.388 0.024   -65.449  1.00 52.92  ? 151 ASN C O     1 
ATOM   9332  C  CB    . ASN C 1 151 ? -32.067 -1.255  -67.522  1.00 52.74  ? 151 ASN C CB    1 
ATOM   9333  C  CG    . ASN C 1 151 ? -32.900 -2.481  -67.201  1.00 55.41  ? 151 ASN C CG    1 
ATOM   9334  O  OD1   . ASN C 1 151 ? -34.132 -2.411  -67.184  1.00 48.74  ? 151 ASN C OD1   1 
ATOM   9335  N  ND2   . ASN C 1 151 ? -32.247 -3.607  -66.959  1.00 58.34  ? 151 ASN C ND2   1 
ATOM   9336  N  N     . GLY C 1 152 ? -35.043 0.706   -66.820  1.00 52.63  ? 152 GLY C N     1 
ATOM   9337  C  CA    . GLY C 1 152 ? -35.991 1.023   -65.763  1.00 44.88  ? 152 GLY C CA    1 
ATOM   9338  C  C     . GLY C 1 152 ? -36.369 -0.130  -64.831  1.00 44.63  ? 152 GLY C C     1 
ATOM   9339  O  O     . GLY C 1 152 ? -36.884 0.135   -63.739  1.00 49.60  ? 152 GLY C O     1 
ATOM   9340  N  N     . TRP C 1 153 ? -36.174 -1.398  -65.246  1.00 48.37  ? 153 TRP C N     1 
ATOM   9341  C  CA    . TRP C 1 153 ? -36.544 -2.554  -64.417  1.00 47.43  ? 153 TRP C CA    1 
ATOM   9342  C  C     . TRP C 1 153 ? -35.424 -2.940  -63.449  1.00 47.85  ? 153 TRP C C     1 
ATOM   9343  O  O     . TRP C 1 153 ? -35.538 -3.929  -62.722  1.00 46.00  ? 153 TRP C O     1 
ATOM   9344  C  CB    . TRP C 1 153 ? -36.957 -3.789  -65.252  1.00 55.28  ? 153 TRP C CB    1 
ATOM   9345  C  CG    . TRP C 1 153 ? -38.409 -3.869  -65.639  1.00 68.59  ? 153 TRP C CG    1 
ATOM   9346  C  CD1   . TRP C 1 153 ? -38.894 -4.100  -66.894  1.00 79.80  ? 153 TRP C CD1   1 
ATOM   9347  C  CD2   . TRP C 1 153 ? -39.571 -3.713  -64.789  1.00 84.61  ? 153 TRP C CD2   1 
ATOM   9348  N  NE1   . TRP C 1 153 ? -40.265 -4.092  -66.890  1.00 86.17  ? 153 TRP C NE1   1 
ATOM   9349  C  CE2   . TRP C 1 153 ? -40.712 -3.859  -65.615  1.00 86.42  ? 153 TRP C CE2   1 
ATOM   9350  C  CE3   . TRP C 1 153 ? -39.770 -3.453  -63.420  1.00 89.05  ? 153 TRP C CE3   1 
ATOM   9351  C  CZ2   . TRP C 1 153 ? -42.015 -3.760  -65.117  1.00 89.91  ? 153 TRP C CZ2   1 
ATOM   9352  C  CZ3   . TRP C 1 153 ? -41.056 -3.354  -62.926  1.00 89.06  ? 153 TRP C CZ3   1 
ATOM   9353  C  CH2   . TRP C 1 153 ? -42.163 -3.507  -63.768  1.00 95.65  ? 153 TRP C CH2   1 
ATOM   9354  N  N     . GLY C 1 154 ? -34.326 -2.186  -63.441  1.00 48.91  ? 154 GLY C N     1 
ATOM   9355  C  CA    . GLY C 1 154 ? -33.204 -2.511  -62.576  1.00 46.92  ? 154 GLY C CA    1 
ATOM   9356  C  C     . GLY C 1 154 ? -33.508 -2.216  -61.113  1.00 45.48  ? 154 GLY C C     1 
ATOM   9357  O  O     . GLY C 1 154 ? -34.524 -1.604  -60.800  1.00 42.93  ? 154 GLY C O     1 
ATOM   9358  N  N     . SER C 1 155 ? -32.650 -2.749  -60.240  1.00 43.80  ? 155 SER C N     1 
ATOM   9359  C  CA    . SER C 1 155 ? -32.710 -2.519  -58.806  1.00 41.47  ? 155 SER C CA    1 
ATOM   9360  C  C     . SER C 1 155 ? -31.996 -1.226  -58.436  1.00 40.88  ? 155 SER C C     1 
ATOM   9361  O  O     . SER C 1 155 ? -30.858 -0.996  -58.847  1.00 43.34  ? 155 SER C O     1 
ATOM   9362  C  CB    . SER C 1 155 ? -32.104 -3.634  -58.072  1.00 37.04  ? 155 SER C CB    1 
ATOM   9363  O  OG    . SER C 1 155 ? -31.856 -3.236  -56.728  1.00 38.94  ? 155 SER C OG    1 
ATOM   9364  N  N     . VAL C 1 156 ? -32.667 -0.410  -57.634  1.00 40.81  ? 156 VAL C N     1 
ATOM   9365  C  CA    . VAL C 1 156 ? -32.050 0.778   -57.079  1.00 43.25  ? 156 VAL C CA    1 
ATOM   9366  C  C     . VAL C 1 156 ? -30.768 0.380   -56.354  1.00 39.63  ? 156 VAL C C     1 
ATOM   9367  O  O     . VAL C 1 156 ? -29.745 1.031   -56.539  1.00 43.96  ? 156 VAL C O     1 
ATOM   9368  C  CB    . VAL C 1 156 ? -32.997 1.544   -56.148  1.00 43.06  ? 156 VAL C CB    1 
ATOM   9369  C  CG1   . VAL C 1 156 ? -32.335 2.814   -55.640  1.00 51.05  ? 156 VAL C CG1   1 
ATOM   9370  C  CG2   . VAL C 1 156 ? -34.318 1.861   -56.834  1.00 44.76  ? 156 VAL C CG2   1 
ATOM   9371  N  N     . VAL C 1 157 ? -30.819 -0.729  -55.611  1.00 36.28  ? 157 VAL C N     1 
ATOM   9372  C  CA    . VAL C 1 157 ? -29.662 -1.235  -54.898  1.00 41.17  ? 157 VAL C CA    1 
ATOM   9373  C  C     . VAL C 1 157 ? -28.628 -1.889  -55.827  1.00 43.52  ? 157 VAL C C     1 
ATOM   9374  O  O     . VAL C 1 157 ? -27.442 -1.534  -55.813  1.00 39.98  ? 157 VAL C O     1 
ATOM   9375  C  CB    . VAL C 1 157 ? -30.110 -2.217  -53.815  1.00 40.76  ? 157 VAL C CB    1 
ATOM   9376  C  CG1   . VAL C 1 157 ? -28.911 -2.822  -53.120  1.00 42.48  ? 157 VAL C CG1   1 
ATOM   9377  C  CG2   . VAL C 1 157 ? -31.036 -1.534  -52.822  1.00 42.42  ? 157 VAL C CG2   1 
ATOM   9378  N  N     . GLY C 1 158 ? -29.057 -2.902  -56.586  1.00 39.77  ? 158 GLY C N     1 
ATOM   9379  C  CA    . GLY C 1 158 ? -28.143 -3.695  -57.396  1.00 39.61  ? 158 GLY C CA    1 
ATOM   9380  C  C     . GLY C 1 158 ? -27.375 -2.821  -58.381  1.00 37.25  ? 158 GLY C C     1 
ATOM   9381  O  O     . GLY C 1 158 ? -26.188 -3.018  -58.596  1.00 41.03  ? 158 GLY C O     1 
ATOM   9382  N  N     . ASN C 1 159 ? -28.065 -1.851  -58.970  1.00 35.56  ? 159 ASN C N     1 
ATOM   9383  C  CA    . ASN C 1 159 ? -27.430 -0.956  -59.918  1.00 43.01  ? 159 ASN C CA    1 
ATOM   9384  C  C     . ASN C 1 159 ? -26.356 -0.121  -59.236  1.00 41.09  ? 159 ASN C C     1 
ATOM   9385  O  O     . ASN C 1 159 ? -25.271 0.021   -59.776  1.00 43.48  ? 159 ASN C O     1 
ATOM   9386  C  CB    . ASN C 1 159 ? -28.433 -0.031  -60.588  1.00 39.34  ? 159 ASN C CB    1 
ATOM   9387  C  CG    . ASN C 1 159 ? -27.798 0.870   -61.616  1.00 40.57  ? 159 ASN C CG    1 
ATOM   9388  O  OD1   . ASN C 1 159 ? -27.316 1.960   -61.302  1.00 45.90  ? 159 ASN C OD1   1 
ATOM   9389  N  ND2   . ASN C 1 159 ? -27.838 0.438   -62.863  1.00 38.41  ? 159 ASN C ND2   1 
ATOM   9390  N  N     . ALA C 1 160 ? -26.697 0.437   -58.071  1.00 39.74  ? 160 ALA C N     1 
ATOM   9391  C  CA    . ALA C 1 160 ? -25.795 1.261   -57.297  1.00 40.26  ? 160 ALA C CA    1 
ATOM   9392  C  C     . ALA C 1 160 ? -24.560 0.453   -56.910  1.00 39.44  ? 160 ALA C C     1 
ATOM   9393  O  O     . ALA C 1 160 ? -23.442 0.922   -57.072  1.00 36.70  ? 160 ALA C O     1 
ATOM   9394  C  CB    . ALA C 1 160 ? -26.499 1.796   -56.076  1.00 41.07  ? 160 ALA C CB    1 
ATOM   9395  N  N     . LEU C 1 161 ? -24.776 -0.772  -56.434  1.00 36.58  ? 161 LEU C N     1 
ATOM   9396  C  CA    . LEU C 1 161 ? -23.688 -1.636  -56.029  1.00 40.46  ? 161 LEU C CA    1 
ATOM   9397  C  C     . LEU C 1 161 ? -22.740 -1.961  -57.183  1.00 39.75  ? 161 LEU C C     1 
ATOM   9398  O  O     . LEU C 1 161 ? -21.566 -2.196  -56.954  1.00 45.38  ? 161 LEU C O     1 
ATOM   9399  C  CB    . LEU C 1 161 ? -24.256 -2.912  -55.410  1.00 37.93  ? 161 LEU C CB    1 
ATOM   9400  C  CG    . LEU C 1 161 ? -24.937 -2.705  -54.057  1.00 40.75  ? 161 LEU C CG    1 
ATOM   9401  C  CD1   . LEU C 1 161 ? -25.439 -4.024  -53.499  1.00 44.59  ? 161 LEU C CD1   1 
ATOM   9402  C  CD2   . LEU C 1 161 ? -24.012 -2.018  -53.059  1.00 43.12  ? 161 LEU C CD2   1 
ATOM   9403  N  N     . ASP C 1 162 ? -23.231 -1.971  -58.413  1.00 38.76  ? 162 ASP C N     1 
ATOM   9404  C  CA    . ASP C 1 162 ? -22.397 -2.291  -59.558  1.00 42.32  ? 162 ASP C CA    1 
ATOM   9405  C  C     . ASP C 1 162 ? -21.856 -1.019  -60.203  1.00 42.19  ? 162 ASP C C     1 
ATOM   9406  O  O     . ASP C 1 162 ? -21.437 -1.040  -61.363  1.00 38.88  ? 162 ASP C O     1 
ATOM   9407  C  CB    . ASP C 1 162 ? -23.202 -3.114  -60.565  1.00 48.23  ? 162 ASP C CB    1 
ATOM   9408  C  CG    . ASP C 1 162 ? -22.328 -3.981  -61.449  1.00 56.41  ? 162 ASP C CG    1 
ATOM   9409  O  OD1   . ASP C 1 162 ? -21.490 -4.735  -60.893  1.00 53.39  ? 162 ASP C OD1   1 
ATOM   9410  O  OD2   . ASP C 1 162 ? -22.511 -3.908  -62.670  1.00 55.22  ? 162 ASP C OD2   1 
ATOM   9411  N  N     . HIS C 1 163 ? -21.923 0.086   -59.453  1.00 35.59  ? 163 HIS C N     1 
ATOM   9412  C  CA    . HIS C 1 163 ? -21.382 1.373   -59.852  1.00 37.26  ? 163 HIS C CA    1 
ATOM   9413  C  C     . HIS C 1 163 ? -22.110 1.884   -61.082  1.00 39.27  ? 163 HIS C C     1 
ATOM   9414  O  O     . HIS C 1 163 ? -21.500 2.481   -61.961  1.00 40.36  ? 163 HIS C O     1 
ATOM   9415  C  CB    . HIS C 1 163 ? -19.865 1.305   -60.097  1.00 39.71  ? 163 HIS C CB    1 
ATOM   9416  C  CG    . HIS C 1 163 ? -19.093 0.881   -58.910  1.00 37.12  ? 163 HIS C CG    1 
ATOM   9417  N  ND1   . HIS C 1 163 ? -17.758 0.541   -58.987  1.00 37.07  ? 163 HIS C ND1   1 
ATOM   9418  C  CD2   . HIS C 1 163 ? -19.455 0.736   -57.625  1.00 35.09  ? 163 HIS C CD2   1 
ATOM   9419  C  CE1   . HIS C 1 163 ? -17.335 0.193   -57.779  1.00 35.88  ? 163 HIS C CE1   1 
ATOM   9420  N  NE2   . HIS C 1 163 ? -18.338 0.327   -56.931  1.00 39.82  ? 163 HIS C NE2   1 
ATOM   9421  N  N     . GLY C 1 164 ? -23.434 1.696   -61.109  1.00 41.05  ? 164 GLY C N     1 
ATOM   9422  C  CA    . GLY C 1 164 ? -24.219 2.104   -62.249  1.00 36.29  ? 164 GLY C CA    1 
ATOM   9423  C  C     . GLY C 1 164 ? -24.378 3.613   -62.304  1.00 41.50  ? 164 GLY C C     1 
ATOM   9424  O  O     . GLY C 1 164 ? -24.043 4.332   -61.363  1.00 45.61  ? 164 GLY C O     1 
ATOM   9425  N  N     . ILE C 1 165 ? -24.915 4.074   -63.427  1.00 43.58  ? 165 ILE C N     1 
ATOM   9426  C  CA    . ILE C 1 165 ? -24.998 5.494   -63.697  1.00 44.81  ? 165 ILE C CA    1 
ATOM   9427  C  C     . ILE C 1 165 ? -26.386 5.801   -64.247  1.00 46.43  ? 165 ILE C C     1 
ATOM   9428  O  O     . ILE C 1 165 ? -27.085 4.919   -64.761  1.00 45.12  ? 165 ILE C O     1 
ATOM   9429  C  CB    . ILE C 1 165 ? -23.870 5.905   -64.663  1.00 50.93  ? 165 ILE C CB    1 
ATOM   9430  C  CG1   . ILE C 1 165 ? -23.960 5.161   -66.002  1.00 54.60  ? 165 ILE C CG1   1 
ATOM   9431  C  CG2   . ILE C 1 165 ? -22.514 5.686   -63.997  1.00 52.33  ? 165 ILE C CG2   1 
ATOM   9432  C  CD1   . ILE C 1 165 ? -23.034 5.709   -67.057  1.00 59.05  ? 165 ILE C CD1   1 
ATOM   9433  N  N     . GLY C 1 166 ? -26.741 7.079   -64.137  1.00 39.47  ? 166 GLY C N     1 
ATOM   9434  C  CA    . GLY C 1 166 ? -27.952 7.630   -64.702  1.00 40.09  ? 166 GLY C CA    1 
ATOM   9435  C  C     . GLY C 1 166 ? -27.663 9.051   -65.140  1.00 41.02  ? 166 GLY C C     1 
ATOM   9436  O  O     . GLY C 1 166 ? -26.499 9.446   -65.205  1.00 42.35  ? 166 GLY C O     1 
ATOM   9437  N  N     . TYR C 1 167 ? -28.725 9.817   -65.377  1.00 38.18  ? 167 TYR C N     1 
ATOM   9438  C  CA    . TYR C 1 167 ? -28.645 10.942  -66.290  1.00 41.86  ? 167 TYR C CA    1 
ATOM   9439  C  C     . TYR C 1 167 ? -29.179 12.233  -65.671  1.00 39.36  ? 167 TYR C C     1 
ATOM   9440  O  O     . TYR C 1 167 ? -29.460 13.197  -66.386  1.00 45.33  ? 167 TYR C O     1 
ATOM   9441  C  CB    . TYR C 1 167 ? -29.299 10.497  -67.598  1.00 39.42  ? 167 TYR C CB    1 
ATOM   9442  C  CG    . TYR C 1 167 ? -28.630 9.259   -68.129  1.00 44.78  ? 167 TYR C CG    1 
ATOM   9443  C  CD1   . TYR C 1 167 ? -27.326 9.298   -68.616  1.00 42.07  ? 167 TYR C CD1   1 
ATOM   9444  C  CD2   . TYR C 1 167 ? -29.236 8.023   -68.008  1.00 42.88  ? 167 TYR C CD2   1 
ATOM   9445  C  CE1   . TYR C 1 167 ? -26.674 8.149   -69.021  1.00 40.70  ? 167 TYR C CE1   1 
ATOM   9446  C  CE2   . TYR C 1 167 ? -28.606 6.867   -68.431  1.00 43.11  ? 167 TYR C CE2   1 
ATOM   9447  C  CZ    . TYR C 1 167 ? -27.316 6.927   -68.928  1.00 45.80  ? 167 TYR C CZ    1 
ATOM   9448  O  OH    . TYR C 1 167 ? -26.702 5.747   -69.297  1.00 50.23  ? 167 TYR C OH    1 
ATOM   9449  N  N     . THR C 1 168 ? -29.285 12.266  -64.342  1.00 41.14  ? 168 THR C N     1 
ATOM   9450  C  CA    . THR C 1 168 ? -29.617 13.499  -63.635  1.00 40.76  ? 168 THR C CA    1 
ATOM   9451  C  C     . THR C 1 168 ? -28.365 14.009  -62.924  1.00 39.92  ? 168 THR C C     1 
ATOM   9452  O  O     . THR C 1 168 ? -27.328 13.358  -62.958  1.00 40.62  ? 168 THR C O     1 
ATOM   9453  C  CB    . THR C 1 168 ? -30.752 13.268  -62.620  1.00 44.46  ? 168 THR C CB    1 
ATOM   9454  O  OG1   . THR C 1 168 ? -30.184 12.683  -61.444  1.00 39.29  ? 168 THR C OG1   1 
ATOM   9455  C  CG2   . THR C 1 168 ? -31.883 12.411  -63.162  1.00 42.26  ? 168 THR C CG2   1 
ATOM   9456  N  N     . PRO C 1 169 ? -28.411 15.126  -62.166  1.00 42.59  ? 169 PRO C N     1 
ATOM   9457  C  CA    . PRO C 1 169 ? -27.279 15.494  -61.311  1.00 46.32  ? 169 PRO C CA    1 
ATOM   9458  C  C     . PRO C 1 169 ? -26.906 14.451  -60.255  1.00 41.53  ? 169 PRO C C     1 
ATOM   9459  O  O     . PRO C 1 169 ? -25.772 14.462  -59.799  1.00 41.48  ? 169 PRO C O     1 
ATOM   9460  C  CB    . PRO C 1 169 ? -27.709 16.818  -60.659  1.00 42.73  ? 169 PRO C CB    1 
ATOM   9461  C  CG    . PRO C 1 169 ? -28.815 17.336  -61.563  1.00 44.87  ? 169 PRO C CG    1 
ATOM   9462  C  CD    . PRO C 1 169 ? -29.516 16.090  -62.064  1.00 44.05  ? 169 PRO C CD    1 
ATOM   9463  N  N     . TYR C 1 170 ? -27.811 13.505  -59.943  1.00 39.18  ? 170 TYR C N     1 
ATOM   9464  C  CA    . TYR C 1 170 ? -27.542 12.413  -59.008  1.00 36.94  ? 170 TYR C CA    1 
ATOM   9465  C  C     . TYR C 1 170 ? -27.181 11.134  -59.772  1.00 36.68  ? 170 TYR C C     1 
ATOM   9466  O  O     . TYR C 1 170 ? -27.420 10.011  -59.320  1.00 37.62  ? 170 TYR C O     1 
ATOM   9467  C  CB    . TYR C 1 170 ? -28.735 12.201  -58.058  1.00 41.24  ? 170 TYR C CB    1 
ATOM   9468  C  CG    . TYR C 1 170 ? -28.915 13.167  -56.897  1.00 37.59  ? 170 TYR C CG    1 
ATOM   9469  C  CD1   . TYR C 1 170 ? -28.812 14.541  -57.063  1.00 38.38  ? 170 TYR C CD1   1 
ATOM   9470  C  CD2   . TYR C 1 170 ? -29.286 12.702  -55.637  1.00 37.78  ? 170 TYR C CD2   1 
ATOM   9471  C  CE1   . TYR C 1 170 ? -29.025 15.427  -56.012  1.00 38.83  ? 170 TYR C CE1   1 
ATOM   9472  C  CE2   . TYR C 1 170 ? -29.524 13.574  -54.581  1.00 36.86  ? 170 TYR C CE2   1 
ATOM   9473  C  CZ    . TYR C 1 170 ? -29.377 14.936  -54.763  1.00 37.84  ? 170 TYR C CZ    1 
ATOM   9474  O  OH    . TYR C 1 170 ? -29.596 15.793  -53.724  1.00 38.19  ? 170 TYR C OH    1 
ATOM   9475  N  N     . GLY C 1 171 ? -26.517 11.308  -60.915  1.00 43.09  ? 171 GLY C N     1 
ATOM   9476  C  CA    . GLY C 1 171 ? -26.279 10.229  -61.865  1.00 45.11  ? 171 GLY C CA    1 
ATOM   9477  C  C     . GLY C 1 171 ? -25.194 9.231   -61.454  1.00 41.12  ? 171 GLY C C     1 
ATOM   9478  O  O     . GLY C 1 171 ? -25.158 8.140   -62.007  1.00 40.78  ? 171 GLY C O     1 
ATOM   9479  N  N     . ASP C 1 172 ? -24.342 9.543   -60.466  1.00 39.04  ? 172 ASP C N     1 
ATOM   9480  C  CA    . ASP C 1 172 ? -23.434 8.532   -59.930  1.00 38.64  ? 172 ASP C CA    1 
ATOM   9481  C  C     . ASP C 1 172 ? -24.137 7.812   -58.777  1.00 36.09  ? 172 ASP C C     1 
ATOM   9482  O  O     . ASP C 1 172 ? -24.170 8.290   -57.649  1.00 37.74  ? 172 ASP C O     1 
ATOM   9483  C  CB    . ASP C 1 172 ? -22.085 9.173   -59.566  1.00 37.85  ? 172 ASP C CB    1 
ATOM   9484  C  CG    . ASP C 1 172 ? -21.033 8.267   -58.956  1.00 39.84  ? 172 ASP C CG    1 
ATOM   9485  O  OD1   . ASP C 1 172 ? -21.329 7.081   -58.624  1.00 37.90  ? 172 ASP C OD1   1 
ATOM   9486  O  OD2   . ASP C 1 172 ? -19.906 8.760   -58.826  1.00 41.40  ? 172 ASP C OD2   1 
ATOM   9487  N  N     . HIS C 1 173 ? -24.696 6.627   -59.045  1.00 38.75  ? 173 HIS C N     1 
ATOM   9488  C  CA    . HIS C 1 173 ? -25.651 6.020   -58.124  1.00 36.07  ? 173 HIS C CA    1 
ATOM   9489  C  C     . HIS C 1 173 ? -24.989 5.628   -56.808  1.00 37.99  ? 173 HIS C C     1 
ATOM   9490  O  O     . HIS C 1 173 ? -25.562 5.828   -55.720  1.00 40.62  ? 173 HIS C O     1 
ATOM   9491  C  CB    . HIS C 1 173 ? -26.323 4.815   -58.787  1.00 40.79  ? 173 HIS C CB    1 
ATOM   9492  C  CG    . HIS C 1 173 ? -27.246 5.211   -59.881  1.00 40.73  ? 173 HIS C CG    1 
ATOM   9493  N  ND1   . HIS C 1 173 ? -27.801 4.293   -60.741  1.00 43.74  ? 173 HIS C ND1   1 
ATOM   9494  C  CD2   . HIS C 1 173 ? -27.679 6.427   -60.287  1.00 48.88  ? 173 HIS C CD2   1 
ATOM   9495  C  CE1   . HIS C 1 173 ? -28.573 4.944   -61.621  1.00 51.65  ? 173 HIS C CE1   1 
ATOM   9496  N  NE2   . HIS C 1 173 ? -28.516 6.246   -61.366  1.00 44.52  ? 173 HIS C NE2   1 
ATOM   9497  N  N     . PHE C 1 174 ? -23.774 5.064   -56.892  1.00 38.63  ? 174 PHE C N     1 
ATOM   9498  C  CA    . PHE C 1 174 ? -23.093 4.667   -55.672  1.00 37.51  ? 174 PHE C CA    1 
ATOM   9499  C  C     . PHE C 1 174 ? -22.619 5.887   -54.876  1.00 34.34  ? 174 PHE C C     1 
ATOM   9500  O  O     . PHE C 1 174 ? -22.607 5.846   -53.645  1.00 36.94  ? 174 PHE C O     1 
ATOM   9501  C  CB    . PHE C 1 174 ? -21.956 3.678   -55.908  1.00 40.08  ? 174 PHE C CB    1 
ATOM   9502  C  CG    . PHE C 1 174 ? -21.526 3.050   -54.611  1.00 42.24  ? 174 PHE C CG    1 
ATOM   9503  C  CD1   . PHE C 1 174 ? -22.383 2.191   -53.931  1.00 40.23  ? 174 PHE C CD1   1 
ATOM   9504  C  CD2   . PHE C 1 174 ? -20.319 3.405   -54.014  1.00 43.51  ? 174 PHE C CD2   1 
ATOM   9505  C  CE1   . PHE C 1 174 ? -22.006 1.641   -52.715  1.00 41.05  ? 174 PHE C CE1   1 
ATOM   9506  C  CE2   . PHE C 1 174 ? -19.949 2.860   -52.796  1.00 42.19  ? 174 PHE C CE2   1 
ATOM   9507  C  CZ    . PHE C 1 174 ? -20.790 1.985   -52.148  1.00 42.57  ? 174 PHE C CZ    1 
ATOM   9508  N  N     . ALA C 1 175 ? -22.310 6.995   -55.540  1.00 35.12  ? 175 ALA C N     1 
ATOM   9509  C  CA    . ALA C 1 175 ? -21.943 8.211   -54.811  1.00 36.10  ? 175 ALA C CA    1 
ATOM   9510  C  C     . ALA C 1 175 ? -23.109 8.688   -53.943  1.00 37.94  ? 175 ALA C C     1 
ATOM   9511  O  O     . ALA C 1 175 ? -22.894 9.293   -52.893  1.00 38.00  ? 175 ALA C O     1 
ATOM   9512  C  CB    . ALA C 1 175 ? -21.517 9.313   -55.757  1.00 35.88  ? 175 ALA C CB    1 
ATOM   9513  N  N     . MET C 1 176 ? -24.346 8.398   -54.377  1.00 42.45  ? 176 MET C N     1 
ATOM   9514  C  CA    . MET C 1 176 ? -25.541 8.889   -53.707  1.00 37.73  ? 176 MET C CA    1 
ATOM   9515  C  C     . MET C 1 176 ? -25.978 7.915   -52.611  1.00 36.24  ? 176 MET C C     1 
ATOM   9516  O  O     . MET C 1 176 ? -26.905 8.201   -51.852  1.00 38.92  ? 176 MET C O     1 
ATOM   9517  C  CB    . MET C 1 176 ? -26.666 9.105   -54.728  1.00 38.03  ? 176 MET C CB    1 
ATOM   9518  C  CG    . MET C 1 176 ? -26.348 10.219  -55.724  1.00 42.08  ? 176 MET C CG    1 
ATOM   9519  S  SD    . MET C 1 176 ? -25.971 11.888  -55.020  1.00 43.85  ? 176 MET C SD    1 
ATOM   9520  C  CE    . MET C 1 176 ? -24.186 11.907  -55.114  1.00 46.03  ? 176 MET C CE    1 
ATOM   9521  N  N     . GLN C 1 177 ? -25.275 6.784   -52.476  1.00 39.17  ? 177 GLN C N     1 
ATOM   9522  C  CA    . GLN C 1 177 ? -25.636 5.786   -51.477  1.00 37.57  ? 177 GLN C CA    1 
ATOM   9523  C  C     . GLN C 1 177 ? -25.281 6.305   -50.087  1.00 41.68  ? 177 GLN C C     1 
ATOM   9524  O  O     . GLN C 1 177 ? -24.298 7.019   -49.930  1.00 39.36  ? 177 GLN C O     1 
ATOM   9525  C  CB    . GLN C 1 177 ? -24.916 4.469   -51.758  1.00 37.36  ? 177 GLN C CB    1 
ATOM   9526  C  CG    . GLN C 1 177 ? -25.158 3.362   -50.739  1.00 39.29  ? 177 GLN C CG    1 
ATOM   9527  C  CD    . GLN C 1 177 ? -24.129 3.275   -49.636  1.00 42.48  ? 177 GLN C CD    1 
ATOM   9528  O  OE1   . GLN C 1 177 ? -23.007 3.745   -49.769  1.00 44.38  ? 177 GLN C OE1   1 
ATOM   9529  N  NE2   . GLN C 1 177 ? -24.505 2.656   -48.528  1.00 41.20  ? 177 GLN C NE2   1 
ATOM   9530  N  N     . CYS C 1 178 ? -26.078 5.929   -49.081  1.00 39.39  ? 178 CYS C N     1 
ATOM   9531  C  CA    . CYS C 1 178 ? -25.823 6.396   -47.732  1.00 37.84  ? 178 CYS C CA    1 
ATOM   9532  C  C     . CYS C 1 178 ? -26.499 5.455   -46.754  1.00 35.07  ? 178 CYS C C     1 
ATOM   9533  O  O     . CYS C 1 178 ? -27.724 5.411   -46.665  1.00 36.25  ? 178 CYS C O     1 
ATOM   9534  C  CB    . CYS C 1 178 ? -26.274 7.843   -47.529  1.00 39.01  ? 178 CYS C CB    1 
ATOM   9535  S  SG    . CYS C 1 178 ? -25.815 8.500   -45.907  1.00 37.19  ? 178 CYS C SG    1 
ATOM   9536  N  N     . GLY C 1 179 ? -25.655 4.686   -46.075  1.00 34.06  ? 179 GLY C N     1 
ATOM   9537  C  CA    . GLY C 1 179 ? -26.076 3.653   -45.146  1.00 34.72  ? 179 GLY C CA    1 
ATOM   9538  C  C     . GLY C 1 179 ? -26.408 2.339   -45.853  1.00 33.34  ? 179 GLY C C     1 
ATOM   9539  O  O     . GLY C 1 179 ? -27.026 2.344   -46.919  1.00 34.34  ? 179 GLY C O     1 
ATOM   9540  N  N     . MET C 1 180 ? -26.000 1.221   -45.249  1.00 35.66  ? 180 MET C N     1 
ATOM   9541  C  CA    . MET C 1 180 ? -26.473 -0.083  -45.699  1.00 36.48  ? 180 MET C CA    1 
ATOM   9542  C  C     . MET C 1 180 ? -26.420 -1.102  -44.566  1.00 37.01  ? 180 MET C C     1 
ATOM   9543  O  O     . MET C 1 180 ? -25.653 -1.006  -43.606  1.00 38.67  ? 180 MET C O     1 
ATOM   9544  C  CB    . MET C 1 180 ? -25.675 -0.631  -46.897  1.00 42.56  ? 180 MET C CB    1 
ATOM   9545  C  CG    . MET C 1 180 ? -24.193 -0.775  -46.638  1.00 43.26  ? 180 MET C CG    1 
ATOM   9546  S  SD    . MET C 1 180 ? -23.252 -1.557  -48.003  1.00 44.00  ? 180 MET C SD    1 
ATOM   9547  C  CE    . MET C 1 180 ? -23.547 -0.351  -49.292  1.00 41.48  ? 180 MET C CE    1 
ATOM   9548  N  N     . GLU C 1 181 ? -27.250 -2.132  -44.736  1.00 38.00  ? 181 GLU C N     1 
ATOM   9549  C  CA    . GLU C 1 181 ? -27.198 -3.335  -43.941  1.00 33.66  ? 181 GLU C CA    1 
ATOM   9550  C  C     . GLU C 1 181 ? -26.651 -4.437  -44.831  1.00 35.88  ? 181 GLU C C     1 
ATOM   9551  O  O     . GLU C 1 181 ? -27.063 -4.576  -45.982  1.00 37.36  ? 181 GLU C O     1 
ATOM   9552  C  CB    . GLU C 1 181 ? -28.601 -3.680  -43.433  1.00 37.34  ? 181 GLU C CB    1 
ATOM   9553  C  CG    . GLU C 1 181 ? -28.681 -4.885  -42.520  1.00 41.13  ? 181 GLU C CG    1 
ATOM   9554  C  CD    . GLU C 1 181 ? -30.117 -5.151  -42.089  1.00 46.63  ? 181 GLU C CD    1 
ATOM   9555  O  OE1   . GLU C 1 181 ? -30.472 -4.770  -40.943  1.00 48.33  ? 181 GLU C OE1   1 
ATOM   9556  O  OE2   . GLU C 1 181 ? -30.898 -5.680  -42.927  1.00 46.49  ? 181 GLU C OE2   1 
ATOM   9557  N  N     . VAL C 1 182 ? -25.762 -5.232  -44.244  1.00 41.34  ? 182 VAL C N     1 
ATOM   9558  C  CA    . VAL C 1 182 ? -25.059 -6.272  -44.960  1.00 41.75  ? 182 VAL C CA    1 
ATOM   9559  C  C     . VAL C 1 182 ? -25.089 -7.534  -44.106  1.00 35.47  ? 182 VAL C C     1 
ATOM   9560  O  O     . VAL C 1 182 ? -24.886 -7.459  -42.908  1.00 33.42  ? 182 VAL C O     1 
ATOM   9561  C  CB    . VAL C 1 182 ? -23.604 -5.841  -45.239  1.00 40.60  ? 182 VAL C CB    1 
ATOM   9562  C  CG1   . VAL C 1 182 ? -22.928 -6.785  -46.211  1.00 43.33  ? 182 VAL C CG1   1 
ATOM   9563  C  CG2   . VAL C 1 182 ? -23.545 -4.411  -45.731  1.00 41.23  ? 182 VAL C CG2   1 
ATOM   9564  N  N     . VAL C 1 183 ? -25.359 -8.675  -44.745  1.00 38.32  ? 183 VAL C N     1 
ATOM   9565  C  CA    . VAL C 1 183 ? -25.068 -9.983  -44.192  1.00 35.83  ? 183 VAL C CA    1 
ATOM   9566  C  C     . VAL C 1 183 ? -23.691 -10.397 -44.704  1.00 33.21  ? 183 VAL C C     1 
ATOM   9567  O  O     . VAL C 1 183 ? -23.471 -10.512 -45.900  1.00 37.59  ? 183 VAL C O     1 
ATOM   9568  C  CB    . VAL C 1 183 ? -26.169 -10.973 -44.608  1.00 37.06  ? 183 VAL C CB    1 
ATOM   9569  C  CG1   . VAL C 1 183 ? -25.877 -12.384 -44.139  1.00 37.53  ? 183 VAL C CG1   1 
ATOM   9570  C  CG2   . VAL C 1 183 ? -27.517 -10.519 -44.103  1.00 38.90  ? 183 VAL C CG2   1 
ATOM   9571  N  N     . LEU C 1 184 ? -22.748 -10.564 -43.793  1.00 35.38  ? 184 LEU C N     1 
ATOM   9572  C  CA    . LEU C 1 184 ? -21.407 -10.958 -44.143  1.00 41.05  ? 184 LEU C CA    1 
ATOM   9573  C  C     . LEU C 1 184 ? -21.415 -12.442 -44.503  1.00 46.84  ? 184 LEU C C     1 
ATOM   9574  O  O     . LEU C 1 184 ? -22.392 -13.156 -44.280  1.00 44.14  ? 184 LEU C O     1 
ATOM   9575  C  CB    . LEU C 1 184 ? -20.487 -10.653 -42.961  1.00 42.70  ? 184 LEU C CB    1 
ATOM   9576  C  CG    . LEU C 1 184 ? -20.410 -9.174  -42.561  1.00 43.06  ? 184 LEU C CG    1 
ATOM   9577  C  CD1   . LEU C 1 184 ? -19.625 -9.019  -41.275  1.00 39.34  ? 184 LEU C CD1   1 
ATOM   9578  C  CD2   . LEU C 1 184 ? -19.798 -8.338  -43.674  1.00 42.89  ? 184 LEU C CD2   1 
ATOM   9579  N  N     . PRO C 1 185 ? -20.333 -12.937 -45.124  1.00 45.32  ? 185 PRO C N     1 
ATOM   9580  C  CA    . PRO C 1 185 ? -20.301 -14.319 -45.603  1.00 49.79  ? 185 PRO C CA    1 
ATOM   9581  C  C     . PRO C 1 185 ? -20.335 -15.372 -44.498  1.00 47.79  ? 185 PRO C C     1 
ATOM   9582  O  O     . PRO C 1 185 ? -20.447 -16.564 -44.781  1.00 47.94  ? 185 PRO C O     1 
ATOM   9583  C  CB    . PRO C 1 185 ? -18.983 -14.368 -46.395  1.00 48.66  ? 185 PRO C CB    1 
ATOM   9584  C  CG    . PRO C 1 185 ? -18.703 -12.910 -46.760  1.00 46.51  ? 185 PRO C CG    1 
ATOM   9585  C  CD    . PRO C 1 185 ? -19.154 -12.152 -45.538  1.00 45.31  ? 185 PRO C CD    1 
ATOM   9586  N  N     . ASN C 1 186 ? -20.212 -14.928 -43.244  1.00 45.27  ? 186 ASN C N     1 
ATOM   9587  C  CA    . ASN C 1 186 ? -20.284 -15.820 -42.092  1.00 44.05  ? 186 ASN C CA    1 
ATOM   9588  C  C     . ASN C 1 186 ? -21.705 -15.836 -41.532  1.00 43.99  ? 186 ASN C C     1 
ATOM   9589  O  O     . ASN C 1 186 ? -21.936 -16.496 -40.529  1.00 45.54  ? 186 ASN C O     1 
ATOM   9590  C  CB    . ASN C 1 186 ? -19.317 -15.415 -40.970  1.00 44.35  ? 186 ASN C CB    1 
ATOM   9591  C  CG    . ASN C 1 186 ? -19.588 -14.021 -40.442  1.00 46.41  ? 186 ASN C CG    1 
ATOM   9592  O  OD1   . ASN C 1 186 ? -20.563 -13.387 -40.847  1.00 42.61  ? 186 ASN C OD1   1 
ATOM   9593  N  ND2   . ASN C 1 186 ? -18.738 -13.539 -39.549  1.00 44.17  ? 186 ASN C ND2   1 
ATOM   9594  N  N     . GLY C 1 187 ? -22.623 -15.070 -42.153  1.00 44.26  ? 187 GLY C N     1 
ATOM   9595  C  CA    . GLY C 1 187 ? -24.007 -14.996 -41.717  1.00 48.17  ? 187 GLY C CA    1 
ATOM   9596  C  C     . GLY C 1 187 ? -24.292 -13.937 -40.645  1.00 45.95  ? 187 GLY C C     1 
ATOM   9597  O  O     . GLY C 1 187 ? -25.450 -13.788 -40.259  1.00 42.61  ? 187 GLY C O     1 
ATOM   9598  N  N     . GLU C 1 188 ? -23.275 -13.185 -40.185  1.00 41.65  ? 188 GLU C N     1 
ATOM   9599  C  CA    . GLU C 1 188 ? -23.519 -12.059 -39.282  1.00 41.08  ? 188 GLU C CA    1 
ATOM   9600  C  C     . GLU C 1 188 ? -24.135 -10.895 -40.043  1.00 44.54  ? 188 GLU C C     1 
ATOM   9601  O  O     . GLU C 1 188 ? -23.946 -10.740 -41.248  1.00 49.91  ? 188 GLU C O     1 
ATOM   9602  C  CB    . GLU C 1 188 ? -22.233 -11.566 -38.623  1.00 43.66  ? 188 GLU C CB    1 
ATOM   9603  C  CG    . GLU C 1 188 ? -21.568 -12.614 -37.747  1.00 47.53  ? 188 GLU C CG    1 
ATOM   9604  C  CD    . GLU C 1 188 ? -22.471 -13.115 -36.633  1.00 47.04  ? 188 GLU C CD    1 
ATOM   9605  O  OE1   . GLU C 1 188 ? -22.798 -12.295 -35.777  1.00 50.62  ? 188 GLU C OE1   1 
ATOM   9606  O  OE2   . GLU C 1 188 ? -22.893 -14.299 -36.654  1.00 48.15  ? 188 GLU C OE2   1 
ATOM   9607  N  N     . VAL C 1 189 ? -24.841 -10.037 -39.319  1.00 45.24  ? 189 VAL C N     1 
ATOM   9608  C  CA    . VAL C 1 189 ? -25.479 -8.894  -39.936  1.00 41.14  ? 189 VAL C CA    1 
ATOM   9609  C  C     . VAL C 1 189 ? -24.827 -7.623  -39.385  1.00 38.14  ? 189 VAL C C     1 
ATOM   9610  O  O     . VAL C 1 189 ? -24.583 -7.540  -38.187  1.00 41.30  ? 189 VAL C O     1 
ATOM   9611  C  CB    . VAL C 1 189 ? -27.000 -8.970  -39.698  1.00 42.79  ? 189 VAL C CB    1 
ATOM   9612  C  CG1   . VAL C 1 189 ? -27.352 -8.926  -38.227  1.00 38.89  ? 189 VAL C CG1   1 
ATOM   9613  C  CG2   . VAL C 1 189 ? -27.742 -7.894  -40.464  1.00 43.85  ? 189 VAL C CG2   1 
ATOM   9614  N  N     . VAL C 1 190 ? -24.535 -6.642  -40.259  1.00 37.94  ? 190 VAL C N     1 
ATOM   9615  C  CA    . VAL C 1 190 ? -23.933 -5.378  -39.846  1.00 40.07  ? 190 VAL C CA    1 
ATOM   9616  C  C     . VAL C 1 190 ? -24.683 -4.228  -40.495  1.00 38.61  ? 190 VAL C C     1 
ATOM   9617  O  O     . VAL C 1 190 ? -25.182 -4.336  -41.622  1.00 36.88  ? 190 VAL C O     1 
ATOM   9618  C  CB    . VAL C 1 190 ? -22.426 -5.236  -40.176  1.00 41.43  ? 190 VAL C CB    1 
ATOM   9619  C  CG1   . VAL C 1 190 ? -21.551 -6.237  -39.457  1.00 42.39  ? 190 VAL C CG1   1 
ATOM   9620  C  CG2   . VAL C 1 190 ? -22.165 -5.318  -41.674  1.00 45.09  ? 190 VAL C CG2   1 
ATOM   9621  N  N     . ARG C 1 191 ? -24.653 -3.094  -39.791  1.00 39.00  ? 191 ARG C N     1 
ATOM   9622  C  CA    . ARG C 1 191 ? -25.055 -1.823  -40.360  1.00 40.03  ? 191 ARG C CA    1 
ATOM   9623  C  C     . ARG C 1 191 ? -23.855 -0.897  -40.419  1.00 33.93  ? 191 ARG C C     1 
ATOM   9624  O  O     . ARG C 1 191 ? -23.071 -0.833  -39.477  1.00 37.21  ? 191 ARG C O     1 
ATOM   9625  C  CB    . ARG C 1 191 ? -26.207 -1.237  -39.558  1.00 42.53  ? 191 ARG C CB    1 
ATOM   9626  C  CG    . ARG C 1 191 ? -27.492 -1.984  -39.844  1.00 44.36  ? 191 ARG C CG    1 
ATOM   9627  C  CD    . ARG C 1 191 ? -28.655 -1.582  -38.986  1.00 43.88  ? 191 ARG C CD    1 
ATOM   9628  N  NE    . ARG C 1 191 ? -29.800 -2.418  -39.339  1.00 43.95  ? 191 ARG C NE    1 
ATOM   9629  C  CZ    . ARG C 1 191 ? -31.067 -2.113  -39.058  1.00 50.65  ? 191 ARG C CZ    1 
ATOM   9630  N  NH1   . ARG C 1 191 ? -31.336 -1.034  -38.342  1.00 46.79  ? 191 ARG C NH1   1 
ATOM   9631  N  NH2   . ARG C 1 191 ? -32.056 -2.889  -39.481  1.00 42.83  ? 191 ARG C NH2   1 
ATOM   9632  N  N     . THR C 1 192 ? -23.731 -0.193  -41.554  1.00 40.62  ? 192 THR C N     1 
ATOM   9633  C  CA    . THR C 1 192 ? -22.639 0.741   -41.787  1.00 39.46  ? 192 THR C CA    1 
ATOM   9634  C  C     . THR C 1 192 ? -23.032 2.152   -41.341  1.00 41.28  ? 192 THR C C     1 
ATOM   9635  O  O     . THR C 1 192 ? -24.212 2.449   -41.146  1.00 37.71  ? 192 THR C O     1 
ATOM   9636  C  CB    . THR C 1 192 ? -22.266 0.805   -43.274  1.00 39.55  ? 192 THR C CB    1 
ATOM   9637  O  OG1   . THR C 1 192 ? -23.363 1.347   -44.016  1.00 34.20  ? 192 THR C OG1   1 
ATOM   9638  C  CG2   . THR C 1 192 ? -21.856 -0.542  -43.820  1.00 42.80  ? 192 THR C CG2   1 
ATOM   9639  N  N     . GLY C 1 193 ? -22.031 3.033   -41.244  1.00 35.39  ? 193 GLY C N     1 
ATOM   9640  C  CA    . GLY C 1 193 ? -22.296 4.439   -41.012  1.00 35.65  ? 193 GLY C CA    1 
ATOM   9641  C  C     . GLY C 1 193 ? -23.029 4.642   -39.695  1.00 34.13  ? 193 GLY C C     1 
ATOM   9642  O  O     . GLY C 1 193 ? -22.744 3.968   -38.714  1.00 36.19  ? 193 GLY C O     1 
ATOM   9643  N  N     . MET C 1 194 ? -23.973 5.576   -39.698  1.00 36.53  ? 194 MET C N     1 
ATOM   9644  C  CA    . MET C 1 194 ? -24.695 5.929   -38.488  1.00 38.82  ? 194 MET C CA    1 
ATOM   9645  C  C     . MET C 1 194 ? -25.655 4.811   -38.088  1.00 40.64  ? 194 MET C C     1 
ATOM   9646  O  O     . MET C 1 194 ? -26.136 4.780   -36.951  1.00 38.07  ? 194 MET C O     1 
ATOM   9647  C  CB    . MET C 1 194 ? -25.495 7.211   -38.695  1.00 37.57  ? 194 MET C CB    1 
ATOM   9648  C  CG    . MET C 1 194 ? -24.633 8.436   -39.066  1.00 39.96  ? 194 MET C CG    1 
ATOM   9649  S  SD    . MET C 1 194 ? -23.247 8.730   -37.960  1.00 40.56  ? 194 MET C SD    1 
ATOM   9650  C  CE    . MET C 1 194 ? -24.080 8.645   -36.375  1.00 41.28  ? 194 MET C CE    1 
ATOM   9651  N  N     . GLY C 1 195 ? -25.931 3.887   -39.019  1.00 36.11  ? 195 GLY C N     1 
ATOM   9652  C  CA    . GLY C 1 195 ? -26.820 2.760   -38.734  1.00 37.80  ? 195 GLY C CA    1 
ATOM   9653  C  C     . GLY C 1 195 ? -26.263 1.779   -37.703  1.00 34.63  ? 195 GLY C C     1 
ATOM   9654  O  O     . GLY C 1 195 ? -27.014 1.020   -37.102  1.00 36.72  ? 195 GLY C O     1 
ATOM   9655  N  N     . ALA C 1 196 ? -24.943 1.819   -37.485  1.00 37.32  ? 196 ALA C N     1 
ATOM   9656  C  CA    . ALA C 1 196 ? -24.294 1.042   -36.447  1.00 32.08  ? 196 ALA C CA    1 
ATOM   9657  C  C     . ALA C 1 196 ? -24.595 1.606   -35.050  1.00 33.85  ? 196 ALA C C     1 
ATOM   9658  O  O     . ALA C 1 196 ? -24.404 0.955   -34.033  1.00 37.27  ? 196 ALA C O     1 
ATOM   9659  C  CB    . ALA C 1 196 ? -22.833 1.025   -36.757  1.00 34.09  ? 196 ALA C CB    1 
ATOM   9660  N  N     . MET C 1 197 ? -25.063 2.846   -34.981  1.00 38.12  ? 197 MET C N     1 
ATOM   9661  C  CA    . MET C 1 197 ? -25.488 3.412   -33.717  1.00 39.11  ? 197 MET C CA    1 
ATOM   9662  C  C     . MET C 1 197 ? -26.990 3.199   -33.553  1.00 37.56  ? 197 MET C C     1 
ATOM   9663  O  O     . MET C 1 197 ? -27.775 3.749   -34.315  1.00 38.30  ? 197 MET C O     1 
ATOM   9664  C  CB    . MET C 1 197 ? -25.204 4.909   -33.626  1.00 39.52  ? 197 MET C CB    1 
ATOM   9665  C  CG    . MET C 1 197 ? -26.094 5.604   -32.611  1.00 44.54  ? 197 MET C CG    1 
ATOM   9666  S  SD    . MET C 1 197 ? -25.656 7.327   -32.396  1.00 48.09  ? 197 MET C SD    1 
ATOM   9667  C  CE    . MET C 1 197 ? -23.995 7.041   -31.780  1.00 62.57  ? 197 MET C CE    1 
ATOM   9668  N  N     . PRO C 1 198 ? -27.436 2.477   -32.506  1.00 41.10  ? 198 PRO C N     1 
ATOM   9669  C  CA    . PRO C 1 198 ? -28.867 2.330   -32.228  1.00 46.69  ? 198 PRO C CA    1 
ATOM   9670  C  C     . PRO C 1 198 ? -29.481 3.688   -31.886  1.00 40.81  ? 198 PRO C C     1 
ATOM   9671  O  O     . PRO C 1 198 ? -28.849 4.510   -31.235  1.00 45.61  ? 198 PRO C O     1 
ATOM   9672  C  CB    . PRO C 1 198 ? -28.925 1.412   -30.998  1.00 44.87  ? 198 PRO C CB    1 
ATOM   9673  C  CG    . PRO C 1 198 ? -27.529 0.861   -30.828  1.00 46.76  ? 198 PRO C CG    1 
ATOM   9674  C  CD    . PRO C 1 198 ? -26.597 1.873   -31.464  1.00 44.66  ? 198 PRO C CD    1 
ATOM   9675  N  N     . GLY C 1 199 ? -30.695 3.931   -32.365  1.00 41.32  ? 199 GLY C N     1 
ATOM   9676  C  CA    . GLY C 1 199 ? -31.442 5.116   -31.990  1.00 41.24  ? 199 GLY C CA    1 
ATOM   9677  C  C     . GLY C 1 199 ? -31.105 6.320   -32.858  1.00 47.04  ? 199 GLY C C     1 
ATOM   9678  O  O     . GLY C 1 199 ? -31.560 7.423   -32.591  1.00 56.68  ? 199 GLY C O     1 
ATOM   9679  N  N     . ASN C 1 200 ? -30.295 6.122   -33.895  1.00 50.77  ? 200 ASN C N     1 
ATOM   9680  C  CA    . ASN C 1 200 ? -29.942 7.206   -34.798  1.00 48.94  ? 200 ASN C CA    1 
ATOM   9681  C  C     . ASN C 1 200 ? -31.153 7.525   -35.676  1.00 43.93  ? 200 ASN C C     1 
ATOM   9682  O  O     . ASN C 1 200 ? -31.924 6.635   -35.990  1.00 36.28  ? 200 ASN C O     1 
ATOM   9683  C  CB    . ASN C 1 200 ? -28.764 6.804   -35.684  1.00 39.78  ? 200 ASN C CB    1 
ATOM   9684  C  CG    . ASN C 1 200 ? -29.261 5.897   -36.785  1.00 42.58  ? 200 ASN C CG    1 
ATOM   9685  O  OD1   . ASN C 1 200 ? -29.749 6.382   -37.808  1.00 46.47  ? 200 ASN C OD1   1 
ATOM   9686  N  ND2   . ASN C 1 200 ? -29.226 4.587   -36.553  1.00 43.87  ? 200 ASN C ND2   1 
ATOM   9687  N  N     . ASN C 1 201 ? -31.294 8.786   -36.091  1.00 42.15  ? 201 ASN C N     1 
ATOM   9688  C  CA    . ASN C 1 201 ? -32.209 9.146   -37.160  1.00 43.19  ? 201 ASN C CA    1 
ATOM   9689  C  C     . ASN C 1 201 ? -31.396 9.637   -38.355  1.00 41.17  ? 201 ASN C C     1 
ATOM   9690  O  O     . ASN C 1 201 ? -31.906 10.402  -39.169  1.00 43.07  ? 201 ASN C O     1 
ATOM   9691  C  CB    . ASN C 1 201 ? -33.220 10.201  -36.720  1.00 44.31  ? 201 ASN C CB    1 
ATOM   9692  C  CG    . ASN C 1 201 ? -34.357 9.593   -35.931  1.00 48.57  ? 201 ASN C CG    1 
ATOM   9693  O  OD1   . ASN C 1 201 ? -34.413 9.719   -34.718  1.00 51.29  ? 201 ASN C OD1   1 
ATOM   9694  N  ND2   . ASN C 1 201 ? -35.222 8.863   -36.602  1.00 48.32  ? 201 ASN C ND2   1 
ATOM   9695  N  N     . THR C 1 202 ? -30.148 9.168   -38.453  1.00 37.42  ? 202 THR C N     1 
ATOM   9696  C  CA    . THR C 1 202 ? -29.162 9.789   -39.326  1.00 36.38  ? 202 THR C CA    1 
ATOM   9697  C  C     . THR C 1 202 ? -28.520 8.826   -40.330  1.00 37.87  ? 202 THR C C     1 
ATOM   9698  O  O     . THR C 1 202 ? -27.627 9.234   -41.060  1.00 37.04  ? 202 THR C O     1 
ATOM   9699  C  CB    . THR C 1 202 ? -28.100 10.460  -38.457  1.00 39.00  ? 202 THR C CB    1 
ATOM   9700  O  OG1   . THR C 1 202 ? -27.475 9.491   -37.610  1.00 36.14  ? 202 THR C OG1   1 
ATOM   9701  C  CG2   . THR C 1 202 ? -28.701 11.579  -37.635  1.00 39.11  ? 202 THR C CG2   1 
ATOM   9702  N  N     . TRP C 1 203 ? -29.008 7.578   -40.418  1.00 35.28  ? 203 TRP C N     1 
ATOM   9703  C  CA    . TRP C 1 203 ? -28.424 6.539   -41.261  1.00 36.44  ? 203 TRP C CA    1 
ATOM   9704  C  C     . TRP C 1 203 ? -28.248 6.975   -42.720  1.00 31.84  ? 203 TRP C C     1 
ATOM   9705  O  O     . TRP C 1 203 ? -27.260 6.630   -43.388  1.00 34.28  ? 203 TRP C O     1 
ATOM   9706  C  CB    . TRP C 1 203 ? -29.322 5.304   -41.195  1.00 35.49  ? 203 TRP C CB    1 
ATOM   9707  C  CG    . TRP C 1 203 ? -28.644 4.029   -41.583  1.00 38.95  ? 203 TRP C CG    1 
ATOM   9708  C  CD1   . TRP C 1 203 ? -27.324 3.823   -41.852  1.00 39.96  ? 203 TRP C CD1   1 
ATOM   9709  C  CD2   . TRP C 1 203 ? -29.286 2.748   -41.706  1.00 37.54  ? 203 TRP C CD2   1 
ATOM   9710  N  NE1   . TRP C 1 203 ? -27.097 2.494   -42.107  1.00 40.13  ? 203 TRP C NE1   1 
ATOM   9711  C  CE2   . TRP C 1 203 ? -28.284 1.811   -42.037  1.00 39.65  ? 203 TRP C CE2   1 
ATOM   9712  C  CE3   . TRP C 1 203 ? -30.613 2.315   -41.600  1.00 34.31  ? 203 TRP C CE3   1 
ATOM   9713  C  CZ2   . TRP C 1 203 ? -28.571 0.453   -42.230  1.00 41.34  ? 203 TRP C CZ2   1 
ATOM   9714  C  CZ3   . TRP C 1 203 ? -30.901 0.983   -41.807  1.00 36.80  ? 203 TRP C CZ3   1 
ATOM   9715  C  CH2   . TRP C 1 203 ? -29.891 0.061   -42.104  1.00 42.32  ? 203 TRP C CH2   1 
ATOM   9716  N  N     . GLN C 1 204 ? -29.250 7.710   -43.199  1.00 32.41  ? 204 GLN C N     1 
ATOM   9717  C  CA    . GLN C 1 204 ? -29.319 8.191   -44.561  1.00 34.51  ? 204 GLN C CA    1 
ATOM   9718  C  C     . GLN C 1 204 ? -28.963 9.679   -44.651  1.00 32.14  ? 204 GLN C C     1 
ATOM   9719  O  O     . GLN C 1 204 ? -29.167 10.278  -45.701  1.00 34.29  ? 204 GLN C O     1 
ATOM   9720  C  CB    . GLN C 1 204 ? -30.723 7.932   -45.121  1.00 35.54  ? 204 GLN C CB    1 
ATOM   9721  C  CG    . GLN C 1 204 ? -30.879 6.549   -45.728  1.00 35.76  ? 204 GLN C CG    1 
ATOM   9722  C  CD    . GLN C 1 204 ? -30.883 5.486   -44.668  1.00 35.50  ? 204 GLN C CD    1 
ATOM   9723  O  OE1   . GLN C 1 204 ? -31.837 5.357   -43.914  1.00 39.71  ? 204 GLN C OE1   1 
ATOM   9724  N  NE2   . GLN C 1 204 ? -29.827 4.690   -44.602  1.00 40.71  ? 204 GLN C NE2   1 
ATOM   9725  N  N     . LEU C 1 205 ? -28.380 10.272  -43.602  1.00 34.06  ? 205 LEU C N     1 
ATOM   9726  C  CA    . LEU C 1 205 ? -28.040 11.689  -43.677  1.00 34.99  ? 205 LEU C CA    1 
ATOM   9727  C  C     . LEU C 1 205 ? -26.530 11.920  -43.712  1.00 33.91  ? 205 LEU C C     1 
ATOM   9728  O  O     . LEU C 1 205 ? -26.086 13.022  -44.021  1.00 37.25  ? 205 LEU C O     1 
ATOM   9729  C  CB    . LEU C 1 205 ? -28.614 12.422  -42.475  1.00 35.15  ? 205 LEU C CB    1 
ATOM   9730  C  CG    . LEU C 1 205 ? -30.124 12.377  -42.291  1.00 38.54  ? 205 LEU C CG    1 
ATOM   9731  C  CD1   . LEU C 1 205 ? -30.476 13.245  -41.102  1.00 40.32  ? 205 LEU C CD1   1 
ATOM   9732  C  CD2   . LEU C 1 205 ? -30.869 12.844  -43.537  1.00 38.23  ? 205 LEU C CD2   1 
ATOM   9733  N  N     . PHE C 1 206 ? -25.755 10.901  -43.372  1.00 34.16  ? 206 PHE C N     1 
ATOM   9734  C  CA    . PHE C 1 206 ? -24.326 11.078  -43.151  1.00 35.55  ? 206 PHE C CA    1 
ATOM   9735  C  C     . PHE C 1 206 ? -23.634 9.755   -43.433  1.00 35.83  ? 206 PHE C C     1 
ATOM   9736  O  O     . PHE C 1 206 ? -23.905 8.765   -42.737  1.00 32.24  ? 206 PHE C O     1 
ATOM   9737  C  CB    . PHE C 1 206 ? -24.083 11.534  -41.712  1.00 36.70  ? 206 PHE C CB    1 
ATOM   9738  C  CG    . PHE C 1 206 ? -22.644 11.862  -41.413  1.00 36.94  ? 206 PHE C CG    1 
ATOM   9739  C  CD1   . PHE C 1 206 ? -22.058 13.010  -41.927  1.00 37.76  ? 206 PHE C CD1   1 
ATOM   9740  C  CD2   . PHE C 1 206 ? -21.875 11.017  -40.624  1.00 37.03  ? 206 PHE C CD2   1 
ATOM   9741  C  CE1   . PHE C 1 206 ? -20.724 13.298  -41.673  1.00 37.10  ? 206 PHE C CE1   1 
ATOM   9742  C  CE2   . PHE C 1 206 ? -20.541 11.300  -40.386  1.00 39.29  ? 206 PHE C CE2   1 
ATOM   9743  C  CZ    . PHE C 1 206 ? -19.974 12.449  -40.897  1.00 37.09  ? 206 PHE C CZ    1 
ATOM   9744  N  N     . LYS C 1 207 ? -22.753 9.755   -44.449  1.00 37.57  ? 207 LYS C N     1 
ATOM   9745  C  CA    . LYS C 1 207 ? -22.196 8.518   -44.980  1.00 39.34  ? 207 LYS C CA    1 
ATOM   9746  C  C     . LYS C 1 207 ? -21.299 7.814   -43.967  1.00 39.84  ? 207 LYS C C     1 
ATOM   9747  O  O     . LYS C 1 207 ? -21.352 6.591   -43.837  1.00 42.26  ? 207 LYS C O     1 
ATOM   9748  C  CB    . LYS C 1 207 ? -21.306 8.748   -46.205  1.00 39.85  ? 207 LYS C CB    1 
ATOM   9749  C  CG    . LYS C 1 207 ? -22.004 9.066   -47.509  1.00 40.80  ? 207 LYS C CG    1 
ATOM   9750  C  CD    . LYS C 1 207 ? -20.984 9.385   -48.572  1.00 39.84  ? 207 LYS C CD    1 
ATOM   9751  C  CE    . LYS C 1 207 ? -21.554 9.463   -49.958  1.00 40.18  ? 207 LYS C CE    1 
ATOM   9752  N  NZ    . LYS C 1 207 ? -21.810 8.112   -50.480  1.00 42.68  ? 207 LYS C NZ    1 
ATOM   9753  N  N     . TYR C 1 208 ? -20.406 8.574   -43.321  1.00 36.32  ? 208 TYR C N     1 
ATOM   9754  C  CA    . TYR C 1 208 ? -19.208 7.971   -42.757  1.00 37.19  ? 208 TYR C CA    1 
ATOM   9755  C  C     . TYR C 1 208 ? -19.471 7.127   -41.518  1.00 34.78  ? 208 TYR C C     1 
ATOM   9756  O  O     . TYR C 1 208 ? -18.850 6.083   -41.341  1.00 37.13  ? 208 TYR C O     1 
ATOM   9757  C  CB    . TYR C 1 208 ? -18.170 9.042   -42.414  1.00 36.04  ? 208 TYR C CB    1 
ATOM   9758  C  CG    . TYR C 1 208 ? -17.630 9.757   -43.624  1.00 38.15  ? 208 TYR C CG    1 
ATOM   9759  C  CD1   . TYR C 1 208 ? -17.143 9.057   -44.719  1.00 41.16  ? 208 TYR C CD1   1 
ATOM   9760  C  CD2   . TYR C 1 208 ? -17.635 11.137  -43.686  1.00 41.11  ? 208 TYR C CD2   1 
ATOM   9761  C  CE1   . TYR C 1 208 ? -16.643 9.715   -45.826  1.00 41.39  ? 208 TYR C CE1   1 
ATOM   9762  C  CE2   . TYR C 1 208 ? -17.156 11.809  -44.794  1.00 39.58  ? 208 TYR C CE2   1 
ATOM   9763  C  CZ    . TYR C 1 208 ? -16.653 11.100  -45.858  1.00 38.80  ? 208 TYR C CZ    1 
ATOM   9764  O  OH    . TYR C 1 208 ? -16.206 11.803  -46.928  1.00 37.00  ? 208 TYR C OH    1 
ATOM   9765  N  N     . GLY C 1 209 ? -20.384 7.590   -40.663  1.00 37.13  ? 209 GLY C N     1 
ATOM   9766  C  CA    . GLY C 1 209 ? -20.333 7.223   -39.266  1.00 36.52  ? 209 GLY C CA    1 
ATOM   9767  C  C     . GLY C 1 209 ? -18.955 7.569   -38.700  1.00 38.42  ? 209 GLY C C     1 
ATOM   9768  O  O     . GLY C 1 209 ? -18.452 8.681   -38.859  1.00 34.12  ? 209 GLY C O     1 
ATOM   9769  N  N     . TYR C 1 210 ? -18.359 6.593   -38.030  1.00 35.76  ? 210 TYR C N     1 
ATOM   9770  C  CA    . TYR C 1 210 ? -17.053 6.750   -37.434  1.00 37.86  ? 210 TYR C CA    1 
ATOM   9771  C  C     . TYR C 1 210 ? -16.204 5.567   -37.864  1.00 34.35  ? 210 TYR C C     1 
ATOM   9772  O  O     . TYR C 1 210 ? -16.730 4.475   -38.082  1.00 34.72  ? 210 TYR C O     1 
ATOM   9773  C  CB    . TYR C 1 210 ? -17.234 6.832   -35.917  1.00 38.72  ? 210 TYR C CB    1 
ATOM   9774  C  CG    . TYR C 1 210 ? -15.975 6.832   -35.093  1.00 40.38  ? 210 TYR C CG    1 
ATOM   9775  C  CD1   . TYR C 1 210 ? -15.094 7.892   -35.168  1.00 40.81  ? 210 TYR C CD1   1 
ATOM   9776  C  CD2   . TYR C 1 210 ? -15.686 5.795   -34.214  1.00 41.38  ? 210 TYR C CD2   1 
ATOM   9777  C  CE1   . TYR C 1 210 ? -13.933 7.906   -34.423  1.00 43.16  ? 210 TYR C CE1   1 
ATOM   9778  C  CE2   . TYR C 1 210 ? -14.530 5.804   -33.452  1.00 43.25  ? 210 TYR C CE2   1 
ATOM   9779  C  CZ    . TYR C 1 210 ? -13.661 6.875   -33.548  1.00 45.66  ? 210 TYR C CZ    1 
ATOM   9780  O  OH    . TYR C 1 210 ? -12.508 6.962   -32.823  1.00 50.22  ? 210 TYR C OH    1 
ATOM   9781  N  N     . GLY C 1 211 ? -14.898 5.807   -37.954  1.00 34.14  ? 211 GLY C N     1 
ATOM   9782  C  CA    . GLY C 1 211 ? -13.944 4.771   -38.302  1.00 36.81  ? 211 GLY C CA    1 
ATOM   9783  C  C     . GLY C 1 211 ? -13.892 4.487   -39.798  1.00 40.09  ? 211 GLY C C     1 
ATOM   9784  O  O     . GLY C 1 211 ? -14.377 5.279   -40.608  1.00 42.53  ? 211 GLY C O     1 
ATOM   9785  N  N     . PRO C 1 212 ? -13.292 3.339   -40.192  1.00 38.47  ? 212 PRO C N     1 
ATOM   9786  C  CA    . PRO C 1 212 ? -13.122 2.989   -41.597  1.00 36.40  ? 212 PRO C CA    1 
ATOM   9787  C  C     . PRO C 1 212 ? -14.442 3.041   -42.365  1.00 38.86  ? 212 PRO C C     1 
ATOM   9788  O  O     . PRO C 1 212 ? -15.469 2.571   -41.869  1.00 40.31  ? 212 PRO C O     1 
ATOM   9789  C  CB    . PRO C 1 212 ? -12.576 1.555   -41.530  1.00 37.78  ? 212 PRO C CB    1 
ATOM   9790  C  CG    . PRO C 1 212 ? -11.909 1.464   -40.194  1.00 40.67  ? 212 PRO C CG    1 
ATOM   9791  C  CD    . PRO C 1 212 ? -12.745 2.328   -39.286  1.00 40.69  ? 212 PRO C CD    1 
ATOM   9792  N  N     . TYR C 1 213 ? -14.395 3.685   -43.537  1.00 35.91  ? 213 TYR C N     1 
ATOM   9793  C  CA    . TYR C 1 213 ? -15.544 3.805   -44.407  1.00 39.62  ? 213 TYR C CA    1 
ATOM   9794  C  C     . TYR C 1 213 ? -15.574 2.586   -45.323  1.00 38.35  ? 213 TYR C C     1 
ATOM   9795  O  O     . TYR C 1 213 ? -14.713 2.458   -46.178  1.00 38.40  ? 213 TYR C O     1 
ATOM   9796  C  CB    . TYR C 1 213 ? -15.458 5.106   -45.201  1.00 43.14  ? 213 TYR C CB    1 
ATOM   9797  C  CG    . TYR C 1 213 ? -16.575 5.267   -46.191  1.00 45.65  ? 213 TYR C CG    1 
ATOM   9798  C  CD1   . TYR C 1 213 ? -17.892 5.216   -45.776  1.00 41.54  ? 213 TYR C CD1   1 
ATOM   9799  C  CD2   . TYR C 1 213 ? -16.320 5.396   -47.543  1.00 57.01  ? 213 TYR C CD2   1 
ATOM   9800  C  CE1   . TYR C 1 213 ? -18.933 5.352   -46.664  1.00 46.02  ? 213 TYR C CE1   1 
ATOM   9801  C  CE2   . TYR C 1 213 ? -17.354 5.505   -48.456  1.00 62.82  ? 213 TYR C CE2   1 
ATOM   9802  C  CZ    . TYR C 1 213 ? -18.664 5.503   -48.011  1.00 56.25  ? 213 TYR C CZ    1 
ATOM   9803  O  OH    . TYR C 1 213 ? -19.693 5.602   -48.899  1.00 53.55  ? 213 TYR C OH    1 
ATOM   9804  N  N     . VAL C 1 214 ? -16.562 1.707   -45.123  1.00 39.96  ? 214 VAL C N     1 
ATOM   9805  C  CA    . VAL C 1 214 ? -16.494 0.351   -45.640  1.00 38.62  ? 214 VAL C CA    1 
ATOM   9806  C  C     . VAL C 1 214 ? -17.616 0.076   -46.642  1.00 37.34  ? 214 VAL C C     1 
ATOM   9807  O  O     . VAL C 1 214 ? -17.672 -1.009  -47.205  1.00 36.73  ? 214 VAL C O     1 
ATOM   9808  C  CB    . VAL C 1 214 ? -16.485 -0.682  -44.499  1.00 40.51  ? 214 VAL C CB    1 
ATOM   9809  C  CG1   . VAL C 1 214 ? -15.194 -0.609  -43.686  1.00 42.18  ? 214 VAL C CG1   1 
ATOM   9810  C  CG2   . VAL C 1 214 ? -17.714 -0.581  -43.596  1.00 43.26  ? 214 VAL C CG2   1 
ATOM   9811  N  N     . ASP C 1 215 ? -18.511 1.031   -46.881  1.00 40.49  ? 215 ASP C N     1 
ATOM   9812  C  CA    . ASP C 1 215 ? -19.671 0.729   -47.704  1.00 42.53  ? 215 ASP C CA    1 
ATOM   9813  C  C     . ASP C 1 215 ? -19.189 0.301   -49.094  1.00 46.75  ? 215 ASP C C     1 
ATOM   9814  O  O     . ASP C 1 215 ? -19.755 -0.621  -49.688  1.00 40.05  ? 215 ASP C O     1 
ATOM   9815  C  CB    . ASP C 1 215 ? -20.648 1.907   -47.779  1.00 43.60  ? 215 ASP C CB    1 
ATOM   9816  C  CG    . ASP C 1 215 ? -21.324 2.263   -46.464  1.00 42.99  ? 215 ASP C CG    1 
ATOM   9817  O  OD1   . ASP C 1 215 ? -20.587 2.590   -45.496  1.00 41.97  ? 215 ASP C OD1   1 
ATOM   9818  O  OD2   . ASP C 1 215 ? -22.603 2.241   -46.422  1.00 41.29  ? 215 ASP C OD2   1 
ATOM   9819  N  N     . GLY C 1 216 ? -18.136 0.983   -49.584  1.00 38.89  ? 216 GLY C N     1 
ATOM   9820  C  CA    . GLY C 1 216 ? -17.558 0.726   -50.897  1.00 34.52  ? 216 GLY C CA    1 
ATOM   9821  C  C     . GLY C 1 216 ? -17.137 -0.725  -51.117  1.00 35.49  ? 216 GLY C C     1 
ATOM   9822  O  O     . GLY C 1 216 ? -17.140 -1.199  -52.260  1.00 36.36  ? 216 GLY C O     1 
ATOM   9823  N  N     . ILE C 1 217 ? -16.722 -1.417  -50.049  1.00 35.32  ? 217 ILE C N     1 
ATOM   9824  C  CA    . ILE C 1 217 ? -16.136 -2.742  -50.209  1.00 38.00  ? 217 ILE C CA    1 
ATOM   9825  C  C     . ILE C 1 217 ? -17.228 -3.737  -50.566  1.00 36.89  ? 217 ILE C C     1 
ATOM   9826  O  O     . ILE C 1 217 ? -16.902 -4.847  -50.958  1.00 37.99  ? 217 ILE C O     1 
ATOM   9827  C  CB    . ILE C 1 217 ? -15.342 -3.217  -48.973  1.00 39.42  ? 217 ILE C CB    1 
ATOM   9828  C  CG1   . ILE C 1 217 ? -16.242 -3.807  -47.875  1.00 42.87  ? 217 ILE C CG1   1 
ATOM   9829  C  CG2   . ILE C 1 217 ? -14.466 -2.104  -48.444  1.00 43.30  ? 217 ILE C CG2   1 
ATOM   9830  C  CD1   . ILE C 1 217 ? -15.501 -4.289  -46.673  1.00 37.36  ? 217 ILE C CD1   1 
ATOM   9831  N  N     . PHE C 1 218 ? -18.498 -3.323  -50.415  1.00 36.84  ? 218 PHE C N     1 
ATOM   9832  C  CA    . PHE C 1 218 ? -19.649 -4.148  -50.716  1.00 38.26  ? 218 PHE C CA    1 
ATOM   9833  C  C     . PHE C 1 218 ? -20.208 -3.852  -52.096  1.00 39.33  ? 218 PHE C C     1 
ATOM   9834  O  O     . PHE C 1 218 ? -21.258 -4.365  -52.451  1.00 41.83  ? 218 PHE C O     1 
ATOM   9835  C  CB    . PHE C 1 218 ? -20.722 -3.945  -49.643  1.00 37.72  ? 218 PHE C CB    1 
ATOM   9836  C  CG    . PHE C 1 218 ? -20.235 -4.456  -48.323  1.00 37.08  ? 218 PHE C CG    1 
ATOM   9837  C  CD1   . PHE C 1 218 ? -19.916 -5.793  -48.186  1.00 39.61  ? 218 PHE C CD1   1 
ATOM   9838  C  CD2   . PHE C 1 218 ? -19.982 -3.600  -47.270  1.00 39.07  ? 218 PHE C CD2   1 
ATOM   9839  C  CE1   . PHE C 1 218 ? -19.398 -6.275  -47.002  1.00 34.94  ? 218 PHE C CE1   1 
ATOM   9840  C  CE2   . PHE C 1 218 ? -19.480 -4.086  -46.076  1.00 39.93  ? 218 PHE C CE2   1 
ATOM   9841  C  CZ    . PHE C 1 218 ? -19.158 -5.413  -45.952  1.00 41.02  ? 218 PHE C CZ    1 
ATOM   9842  N  N     . SER C 1 219 ? -19.527 -2.999  -52.857  1.00 39.20  ? 219 SER C N     1 
ATOM   9843  C  CA    . SER C 1 219 ? -19.944 -2.689  -54.204  1.00 37.62  ? 219 SER C CA    1 
ATOM   9844  C  C     . SER C 1 219 ? -19.002 -3.410  -55.150  1.00 37.44  ? 219 SER C C     1 
ATOM   9845  O  O     . SER C 1 219 ? -17.819 -3.555  -54.830  1.00 37.77  ? 219 SER C O     1 
ATOM   9846  C  CB    . SER C 1 219 ? -19.921 -1.186  -54.394  1.00 39.25  ? 219 SER C CB    1 
ATOM   9847  O  OG    . SER C 1 219 ? -18.591 -0.696  -54.265  1.00 43.96  ? 219 SER C OG    1 
ATOM   9848  N  N     . GLN C 1 220 ? -19.525 -3.821  -56.313  1.00 40.43  ? 220 GLN C N     1 
ATOM   9849  C  CA    . GLN C 1 220 ? -18.833 -4.703  -57.250  1.00 41.64  ? 220 GLN C CA    1 
ATOM   9850  C  C     . GLN C 1 220 ? -18.031 -5.778  -56.508  1.00 43.72  ? 220 GLN C C     1 
ATOM   9851  O  O     . GLN C 1 220 ? -16.837 -5.980  -56.771  1.00 36.71  ? 220 GLN C O     1 
ATOM   9852  C  CB    . GLN C 1 220 ? -17.945 -3.879  -58.182  1.00 43.72  ? 220 GLN C CB    1 
ATOM   9853  C  CG    . GLN C 1 220 ? -18.731 -3.128  -59.247  1.00 43.87  ? 220 GLN C CG    1 
ATOM   9854  C  CD    . GLN C 1 220 ? -17.864 -2.658  -60.390  1.00 37.88  ? 220 GLN C CD    1 
ATOM   9855  O  OE1   . GLN C 1 220 ? -16.636 -2.689  -60.324  1.00 42.88  ? 220 GLN C OE1   1 
ATOM   9856  N  NE2   . GLN C 1 220 ? -18.505 -2.170  -61.435  1.00 33.88  ? 220 GLN C NE2   1 
ATOM   9857  N  N     . SER C 1 221 ? -18.714 -6.524  -55.626  1.00 38.53  ? 221 SER C N     1 
ATOM   9858  C  CA    . SER C 1 221 ? -18.023 -7.260  -54.578  1.00 38.85  ? 221 SER C CA    1 
ATOM   9859  C  C     . SER C 1 221 ? -18.691 -8.586  -54.269  1.00 38.90  ? 221 SER C C     1 
ATOM   9860  O  O     . SER C 1 221 ? -19.861 -8.738  -54.539  1.00 40.11  ? 221 SER C O     1 
ATOM   9861  C  CB    . SER C 1 221 ? -18.008 -6.464  -53.328  1.00 41.10  ? 221 SER C CB    1 
ATOM   9862  O  OG    . SER C 1 221 ? -17.336 -7.170  -52.311  1.00 44.40  ? 221 SER C OG    1 
ATOM   9863  N  N     . ASN C 1 222 ? -17.966 -9.467  -53.576  1.00 45.09  ? 222 ASN C N     1 
ATOM   9864  C  CA    . ASN C 1 222 ? -18.536 -10.677 -53.001  1.00 45.39  ? 222 ASN C CA    1 
ATOM   9865  C  C     . ASN C 1 222 ? -18.120 -10.783 -51.536  1.00 43.77  ? 222 ASN C C     1 
ATOM   9866  O  O     . ASN C 1 222 ? -17.901 -11.882 -51.014  1.00 40.64  ? 222 ASN C O     1 
ATOM   9867  C  CB    . ASN C 1 222 ? -18.135 -11.922 -53.800  1.00 45.62  ? 222 ASN C CB    1 
ATOM   9868  C  CG    . ASN C 1 222 ? -16.642 -12.057 -54.010  1.00 43.33  ? 222 ASN C CG    1 
ATOM   9869  O  OD1   . ASN C 1 222 ? -15.846 -11.288 -53.472  1.00 41.48  ? 222 ASN C OD1   1 
ATOM   9870  N  ND2   . ASN C 1 222 ? -16.254 -13.046 -54.803  1.00 42.94  ? 222 ASN C ND2   1 
ATOM   9871  N  N     . PHE C 1 223 ? -18.007 -9.618  -50.885  1.00 40.57  ? 223 PHE C N     1 
ATOM   9872  C  CA    . PHE C 1 223 ? -17.642 -9.551  -49.483  1.00 39.23  ? 223 PHE C CA    1 
ATOM   9873  C  C     . PHE C 1 223 ? -18.890 -9.565  -48.588  1.00 34.98  ? 223 PHE C C     1 
ATOM   9874  O  O     . PHE C 1 223 ? -18.770 -9.693  -47.383  1.00 37.51  ? 223 PHE C O     1 
ATOM   9875  C  CB    . PHE C 1 223 ? -16.824 -8.284  -49.229  1.00 45.08  ? 223 PHE C CB    1 
ATOM   9876  C  CG    . PHE C 1 223 ? -15.466 -8.206  -49.882  1.00 41.55  ? 223 PHE C CG    1 
ATOM   9877  C  CD1   . PHE C 1 223 ? -14.883 -9.299  -50.497  1.00 43.90  ? 223 PHE C CD1   1 
ATOM   9878  C  CD2   . PHE C 1 223 ? -14.792 -7.001  -49.913  1.00 40.03  ? 223 PHE C CD2   1 
ATOM   9879  C  CE1   . PHE C 1 223 ? -13.631 -9.190  -51.086  1.00 43.24  ? 223 PHE C CE1   1 
ATOM   9880  C  CE2   . PHE C 1 223 ? -13.549 -6.895  -50.514  1.00 40.90  ? 223 PHE C CE2   1 
ATOM   9881  C  CZ    . PHE C 1 223 ? -12.970 -7.992  -51.086  1.00 39.87  ? 223 PHE C CZ    1 
ATOM   9882  N  N     . GLY C 1 224 ? -20.089 -9.421  -49.160  1.00 35.91  ? 224 GLY C N     1 
ATOM   9883  C  CA    . GLY C 1 224 ? -21.295 -9.552  -48.360  1.00 33.51  ? 224 GLY C CA    1 
ATOM   9884  C  C     . GLY C 1 224 ? -22.547 -9.455  -49.210  1.00 35.96  ? 224 GLY C C     1 
ATOM   9885  O  O     . GLY C 1 224 ? -22.455 -9.173  -50.383  1.00 41.70  ? 224 GLY C O     1 
ATOM   9886  N  N     . VAL C 1 225 ? -23.719 -9.653  -48.587  1.00 42.99  ? 225 VAL C N     1 
ATOM   9887  C  CA    . VAL C 1 225 ? -25.018 -9.496  -49.225  1.00 35.92  ? 225 VAL C CA    1 
ATOM   9888  C  C     . VAL C 1 225 ? -25.719 -8.267  -48.639  1.00 38.50  ? 225 VAL C C     1 
ATOM   9889  O  O     . VAL C 1 225 ? -26.119 -8.259  -47.480  1.00 38.72  ? 225 VAL C O     1 
ATOM   9890  C  CB    . VAL C 1 225 ? -25.898 -10.744 -49.009  1.00 39.66  ? 225 VAL C CB    1 
ATOM   9891  C  CG1   . VAL C 1 225 ? -27.226 -10.617 -49.737  1.00 43.10  ? 225 VAL C CG1   1 
ATOM   9892  C  CG2   . VAL C 1 225 ? -25.192 -12.035 -49.400  1.00 44.74  ? 225 VAL C CG2   1 
ATOM   9893  N  N     . VAL C 1 226 ? -25.942 -7.248  -49.457  1.00 37.57  ? 226 VAL C N     1 
ATOM   9894  C  CA    . VAL C 1 226 ? -26.606 -6.051  -48.993  1.00 40.53  ? 226 VAL C CA    1 
ATOM   9895  C  C     . VAL C 1 226 ? -28.123 -6.286  -48.928  1.00 41.55  ? 226 VAL C C     1 
ATOM   9896  O  O     . VAL C 1 226 ? -28.738 -6.586  -49.937  1.00 38.26  ? 226 VAL C O     1 
ATOM   9897  C  CB    . VAL C 1 226 ? -26.257 -4.896  -49.941  1.00 41.70  ? 226 VAL C CB    1 
ATOM   9898  C  CG1   . VAL C 1 226 ? -27.029 -3.642  -49.575  1.00 42.86  ? 226 VAL C CG1   1 
ATOM   9899  C  CG2   . VAL C 1 226 ? -24.754 -4.636  -49.973  1.00 41.69  ? 226 VAL C CG2   1 
ATOM   9900  N  N     . THR C 1 227 ? -28.745 -6.021  -47.768  1.00 44.38  ? 227 THR C N     1 
ATOM   9901  C  CA    . THR C 1 227 ? -30.165 -6.255  -47.543  1.00 41.07  ? 227 THR C CA    1 
ATOM   9902  C  C     . THR C 1 227 ? -30.977 -4.972  -47.399  1.00 45.55  ? 227 THR C C     1 
ATOM   9903  O  O     . THR C 1 227 ? -32.204 -5.001  -47.569  1.00 42.02  ? 227 THR C O     1 
ATOM   9904  C  CB    . THR C 1 227 ? -30.362 -7.093  -46.288  1.00 41.39  ? 227 THR C CB    1 
ATOM   9905  O  OG1   . THR C 1 227 ? -29.673 -6.400  -45.247  1.00 38.17  ? 227 THR C OG1   1 
ATOM   9906  C  CG2   . THR C 1 227 ? -29.816 -8.498  -46.452  1.00 42.29  ? 227 THR C CG2   1 
ATOM   9907  N  N     . LYS C 1 228 ? -30.304 -3.857  -47.081  1.00 42.54  ? 228 LYS C N     1 
ATOM   9908  C  CA    . LYS C 1 228 ? -30.952 -2.555  -47.060  1.00 39.60  ? 228 LYS C CA    1 
ATOM   9909  C  C     . LYS C 1 228 ? -29.927 -1.539  -47.534  1.00 38.45  ? 228 LYS C C     1 
ATOM   9910  O  O     . LYS C 1 228 ? -28.747 -1.683  -47.252  1.00 36.29  ? 228 LYS C O     1 
ATOM   9911  C  CB    . LYS C 1 228 ? -31.437 -2.193  -45.648  1.00 42.65  ? 228 LYS C CB    1 
ATOM   9912  C  CG    . LYS C 1 228 ? -32.371 -3.205  -44.987  1.00 40.55  ? 228 LYS C CG    1 
ATOM   9913  C  CD    . LYS C 1 228 ? -32.819 -2.820  -43.570  1.00 43.78  ? 228 LYS C CD    1 
ATOM   9914  C  CE    . LYS C 1 228 ? -33.951 -3.695  -43.055  1.00 42.29  ? 228 LYS C CE    1 
ATOM   9915  N  NZ    . LYS C 1 228 ? -33.497 -5.090  -42.839  1.00 43.20  ? 228 LYS C NZ    1 
ATOM   9916  N  N     . MET C 1 229 ? -30.388 -0.486  -48.201  1.00 38.60  ? 229 MET C N     1 
ATOM   9917  C  CA    . MET C 1 229 ? -29.477 0.534   -48.659  1.00 39.85  ? 229 MET C CA    1 
ATOM   9918  C  C     . MET C 1 229 ? -30.213 1.861   -48.684  1.00 39.34  ? 229 MET C C     1 
ATOM   9919  O  O     . MET C 1 229 ? -31.354 1.949   -49.147  1.00 37.28  ? 229 MET C O     1 
ATOM   9920  C  CB    . MET C 1 229 ? -28.968 0.210   -50.069  1.00 41.83  ? 229 MET C CB    1 
ATOM   9921  C  CG    . MET C 1 229 ? -27.822 1.072   -50.493  1.00 38.11  ? 229 MET C CG    1 
ATOM   9922  S  SD    . MET C 1 229 ? -27.392 0.861   -52.254  1.00 41.74  ? 229 MET C SD    1 
ATOM   9923  C  CE    . MET C 1 229 ? -28.552 2.039   -52.944  1.00 40.89  ? 229 MET C CE    1 
ATOM   9924  N  N     . GLY C 1 230 ? -29.550 2.890   -48.163  1.00 34.52  ? 230 GLY C N     1 
ATOM   9925  C  CA    . GLY C 1 230 ? -30.060 4.233   -48.355  1.00 33.96  ? 230 GLY C CA    1 
ATOM   9926  C  C     . GLY C 1 230 ? -29.534 4.809   -49.646  1.00 34.28  ? 230 GLY C C     1 
ATOM   9927  O  O     . GLY C 1 230 ? -28.431 4.468   -50.104  1.00 37.91  ? 230 GLY C O     1 
ATOM   9928  N  N     . ILE C 1 231 ? -30.288 5.756   -50.178  1.00 35.58  ? 231 ILE C N     1 
ATOM   9929  C  CA    . ILE C 1 231 ? -29.809 6.548   -51.293  1.00 37.34  ? 231 ILE C CA    1 
ATOM   9930  C  C     . ILE C 1 231 ? -30.409 7.946   -51.203  1.00 38.44  ? 231 ILE C C     1 
ATOM   9931  O  O     . ILE C 1 231 ? -31.570 8.123   -50.854  1.00 38.34  ? 231 ILE C O     1 
ATOM   9932  C  CB    . ILE C 1 231 ? -30.183 5.864   -52.614  1.00 41.06  ? 231 ILE C CB    1 
ATOM   9933  C  CG1   . ILE C 1 231 ? -29.485 6.527   -53.798  1.00 44.31  ? 231 ILE C CG1   1 
ATOM   9934  C  CG2   . ILE C 1 231 ? -31.699 5.844   -52.793  1.00 40.70  ? 231 ILE C CG2   1 
ATOM   9935  C  CD1   . ILE C 1 231 ? -29.575 5.721   -55.054  1.00 47.19  ? 231 ILE C CD1   1 
ATOM   9936  N  N     . TRP C 1 232 ? -29.614 8.926   -51.590  1.00 36.62  ? 232 TRP C N     1 
ATOM   9937  C  CA    . TRP C 1 232 ? -30.029 10.314  -51.568  1.00 39.27  ? 232 TRP C CA    1 
ATOM   9938  C  C     . TRP C 1 232 ? -30.809 10.604  -52.842  1.00 37.60  ? 232 TRP C C     1 
ATOM   9939  O  O     . TRP C 1 232 ? -30.432 10.154  -53.917  1.00 38.79  ? 232 TRP C O     1 
ATOM   9940  C  CB    . TRP C 1 232 ? -28.800 11.226  -51.444  1.00 39.23  ? 232 TRP C CB    1 
ATOM   9941  C  CG    . TRP C 1 232 ? -28.082 11.143  -50.128  1.00 41.19  ? 232 TRP C CG    1 
ATOM   9942  C  CD1   . TRP C 1 232 ? -28.610 10.784  -48.921  1.00 38.99  ? 232 TRP C CD1   1 
ATOM   9943  C  CD2   . TRP C 1 232 ? -26.691 11.430  -49.887  1.00 38.94  ? 232 TRP C CD2   1 
ATOM   9944  N  NE1   . TRP C 1 232 ? -27.651 10.840  -47.953  1.00 38.92  ? 232 TRP C NE1   1 
ATOM   9945  C  CE2   . TRP C 1 232 ? -26.462 11.230  -48.514  1.00 36.59  ? 232 TRP C CE2   1 
ATOM   9946  C  CE3   . TRP C 1 232 ? -25.626 11.857  -50.694  1.00 41.12  ? 232 TRP C CE3   1 
ATOM   9947  C  CZ2   . TRP C 1 232 ? -25.213 11.439  -47.930  1.00 35.57  ? 232 TRP C CZ2   1 
ATOM   9948  C  CZ3   . TRP C 1 232 ? -24.385 12.032  -50.129  1.00 39.58  ? 232 TRP C CZ3   1 
ATOM   9949  C  CH2   . TRP C 1 232 ? -24.182 11.817  -48.763  1.00 39.71  ? 232 TRP C CH2   1 
ATOM   9950  N  N     . LEU C 1 233 ? -31.869 11.401  -52.703  1.00 40.81  ? 233 LEU C N     1 
ATOM   9951  C  CA    . LEU C 1 233 ? -32.756 11.752  -53.802  1.00 35.44  ? 233 LEU C CA    1 
ATOM   9952  C  C     . LEU C 1 233 ? -32.769 13.269  -53.945  1.00 33.67  ? 233 LEU C C     1 
ATOM   9953  O  O     . LEU C 1 233 ? -32.931 13.963  -52.958  1.00 37.37  ? 233 LEU C O     1 
ATOM   9954  C  CB    . LEU C 1 233 ? -34.155 11.230  -53.456  1.00 39.37  ? 233 LEU C CB    1 
ATOM   9955  C  CG    . LEU C 1 233 ? -34.295 9.720   -53.259  1.00 38.53  ? 233 LEU C CG    1 
ATOM   9956  C  CD1   . LEU C 1 233 ? -35.742 9.365   -52.942  1.00 38.32  ? 233 LEU C CD1   1 
ATOM   9957  C  CD2   . LEU C 1 233 ? -33.814 8.934   -54.484  1.00 38.03  ? 233 LEU C CD2   1 
ATOM   9958  N  N     . MET C 1 234 ? -32.657 13.762  -55.183  1.00 37.01  ? 234 MET C N     1 
ATOM   9959  C  CA    . MET C 1 234 ? -32.659 15.181  -55.481  1.00 41.80  ? 234 MET C CA    1 
ATOM   9960  C  C     . MET C 1 234 ? -34.050 15.792  -55.263  1.00 46.74  ? 234 MET C C     1 
ATOM   9961  O  O     . MET C 1 234 ? -35.059 15.280  -55.743  1.00 39.36  ? 234 MET C O     1 
ATOM   9962  C  CB    . MET C 1 234 ? -32.235 15.409  -56.933  1.00 42.23  ? 234 MET C CB    1 
ATOM   9963  C  CG    . MET C 1 234 ? -31.904 16.851  -57.238  1.00 42.70  ? 234 MET C CG    1 
ATOM   9964  S  SD    . MET C 1 234 ? -31.389 17.075  -58.960  1.00 50.11  ? 234 MET C SD    1 
ATOM   9965  C  CE    . MET C 1 234 ? -32.911 16.777  -59.856  1.00 51.14  ? 234 MET C CE    1 
ATOM   9966  N  N     . PRO C 1 235 ? -34.156 16.926  -54.535  1.00 43.83  ? 235 PRO C N     1 
ATOM   9967  C  CA    . PRO C 1 235 ? -35.418 17.655  -54.445  1.00 45.42  ? 235 PRO C CA    1 
ATOM   9968  C  C     . PRO C 1 235 ? -35.811 18.104  -55.841  1.00 46.18  ? 235 PRO C C     1 
ATOM   9969  O  O     . PRO C 1 235 ? -34.953 18.377  -56.673  1.00 40.96  ? 235 PRO C O     1 
ATOM   9970  C  CB    . PRO C 1 235 ? -35.125 18.861  -53.533  1.00 41.73  ? 235 PRO C CB    1 
ATOM   9971  C  CG    . PRO C 1 235 ? -33.894 18.446  -52.775  1.00 41.31  ? 235 PRO C CG    1 
ATOM   9972  C  CD    . PRO C 1 235 ? -33.109 17.543  -53.714  1.00 40.00  ? 235 PRO C CD    1 
ATOM   9973  N  N     . GLU C 1 236 ? -37.120 18.176  -56.080  1.00 44.51  ? 236 GLU C N     1 
ATOM   9974  C  CA    . GLU C 1 236 ? -37.608 18.690  -57.335  1.00 45.08  ? 236 GLU C CA    1 
ATOM   9975  C  C     . GLU C 1 236 ? -37.033 20.087  -57.524  1.00 43.42  ? 236 GLU C C     1 
ATOM   9976  O  O     . GLU C 1 236 ? -37.178 20.927  -56.653  1.00 43.54  ? 236 GLU C O     1 
ATOM   9977  C  CB    . GLU C 1 236 ? -39.136 18.741  -57.321  1.00 51.66  ? 236 GLU C CB    1 
ATOM   9978  C  CG    . GLU C 1 236 ? -39.737 19.110  -58.659  1.00 60.52  ? 236 GLU C CG    1 
ATOM   9979  C  CD    . GLU C 1 236 ? -41.236 19.325  -58.560  1.00 64.26  ? 236 GLU C CD    1 
ATOM   9980  O  OE1   . GLU C 1 236 ? -41.643 20.425  -58.160  1.00 69.16  ? 236 GLU C OE1   1 
ATOM   9981  O  OE2   . GLU C 1 236 ? -41.970 18.371  -58.789  1.00 61.84  ? 236 GLU C OE2   1 
ATOM   9982  N  N     . PRO C 1 237 ? -36.367 20.382  -58.655  1.00 39.90  ? 237 PRO C N     1 
ATOM   9983  C  CA    . PRO C 1 237 ? -35.837 21.715  -58.897  1.00 43.96  ? 237 PRO C CA    1 
ATOM   9984  C  C     . PRO C 1 237 ? -36.925 22.667  -59.380  1.00 47.98  ? 237 PRO C C     1 
ATOM   9985  O  O     . PRO C 1 237 ? -38.018 22.244  -59.732  1.00 50.16  ? 237 PRO C O     1 
ATOM   9986  C  CB    . PRO C 1 237 ? -34.772 21.458  -59.975  1.00 46.13  ? 237 PRO C CB    1 
ATOM   9987  C  CG    . PRO C 1 237 ? -35.324 20.298  -60.753  1.00 49.27  ? 237 PRO C CG    1 
ATOM   9988  C  CD    . PRO C 1 237 ? -36.052 19.439  -59.736  1.00 41.24  ? 237 PRO C CD    1 
ATOM   9989  N  N     . ALA C 1 238 ? -36.582 23.953  -59.390  1.00 47.11  ? 238 ALA C N     1 
ATOM   9990  C  CA    . ALA C 1 238 ? -37.507 25.036  -59.672  1.00 46.04  ? 238 ALA C CA    1 
ATOM   9991  C  C     . ALA C 1 238 ? -37.761 25.177  -61.170  1.00 50.00  ? 238 ALA C C     1 
ATOM   9992  O  O     . ALA C 1 238 ? -38.671 25.897  -61.564  1.00 61.51  ? 238 ALA C O     1 
ATOM   9993  C  CB    . ALA C 1 238 ? -36.914 26.312  -59.130  1.00 44.48  ? 238 ALA C CB    1 
ATOM   9994  N  N     . GLY C 1 239 ? -36.891 24.579  -61.995  1.00 56.33  ? 239 GLY C N     1 
ATOM   9995  C  CA    . GLY C 1 239 ? -36.995 24.617  -63.448  1.00 47.44  ? 239 GLY C CA    1 
ATOM   9996  C  C     . GLY C 1 239 ? -36.206 23.464  -64.076  1.00 49.77  ? 239 GLY C C     1 
ATOM   9997  O  O     . GLY C 1 239 ? -35.368 22.842  -63.421  1.00 49.28  ? 239 GLY C O     1 
ATOM   9998  N  N     . TYR C 1 240 ? -36.484 23.170  -65.344  1.00 44.86  ? 240 TYR C N     1 
ATOM   9999  C  CA    . TYR C 1 240 ? -35.858 22.049  -66.022  1.00 45.44  ? 240 TYR C CA    1 
ATOM   10000 C  C     . TYR C 1 240 ? -36.002 22.253  -67.514  1.00 50.82  ? 240 TYR C C     1 
ATOM   10001 O  O     . TYR C 1 240 ? -37.125 22.465  -67.979  1.00 53.59  ? 240 TYR C O     1 
ATOM   10002 C  CB    . TYR C 1 240 ? -36.501 20.723  -65.614  1.00 42.12  ? 240 TYR C CB    1 
ATOM   10003 C  CG    . TYR C 1 240 ? -36.068 19.530  -66.435  1.00 47.49  ? 240 TYR C CG    1 
ATOM   10004 C  CD1   . TYR C 1 240 ? -34.756 19.077  -66.384  1.00 50.61  ? 240 TYR C CD1   1 
ATOM   10005 C  CD2   . TYR C 1 240 ? -36.951 18.837  -67.252  1.00 47.87  ? 240 TYR C CD2   1 
ATOM   10006 C  CE1   . TYR C 1 240 ? -34.324 17.990  -67.129  1.00 43.00  ? 240 TYR C CE1   1 
ATOM   10007 C  CE2   . TYR C 1 240 ? -36.540 17.733  -67.991  1.00 51.55  ? 240 TYR C CE2   1 
ATOM   10008 C  CZ    . TYR C 1 240 ? -35.222 17.300  -67.921  1.00 49.32  ? 240 TYR C CZ    1 
ATOM   10009 O  OH    . TYR C 1 240 ? -34.749 16.227  -68.643  1.00 45.82  ? 240 TYR C OH    1 
ATOM   10010 N  N     . ARG C 1 241 ? -34.873 22.160  -68.233  1.00 51.41  ? 241 ARG C N     1 
ATOM   10011 C  CA    . ARG C 1 241 ? -34.836 22.371  -69.671  1.00 45.91  ? 241 ARG C CA    1 
ATOM   10012 C  C     . ARG C 1 241 ? -33.853 21.423  -70.351  1.00 51.81  ? 241 ARG C C     1 
ATOM   10013 O  O     . ARG C 1 241 ? -32.653 21.697  -70.345  1.00 55.20  ? 241 ARG C O     1 
ATOM   10014 C  CB    . ARG C 1 241 ? -34.406 23.806  -69.977  1.00 51.07  ? 241 ARG C CB    1 
ATOM   10015 C  CG    . ARG C 1 241 ? -35.548 24.800  -69.876  1.00 60.23  ? 241 ARG C CG    1 
ATOM   10016 C  CD    . ARG C 1 241 ? -36.456 24.676  -71.089  1.00 68.56  ? 241 ARG C CD    1 
ATOM   10017 N  NE    . ARG C 1 241 ? -36.112 25.625  -72.136  1.00 74.03  ? 241 ARG C NE    1 
ATOM   10018 C  CZ    . ARG C 1 241 ? -36.745 25.725  -73.294  1.00 66.59  ? 241 ARG C CZ    1 
ATOM   10019 N  NH1   . ARG C 1 241 ? -37.665 24.838  -73.622  1.00 72.34  ? 241 ARG C NH1   1 
ATOM   10020 N  NH2   . ARG C 1 241 ? -36.425 26.690  -74.134  1.00 68.61  ? 241 ARG C NH2   1 
ATOM   10021 N  N     . PRO C 1 242 ? -34.322 20.331  -71.011  1.00 55.09  ? 242 PRO C N     1 
ATOM   10022 C  CA    . PRO C 1 242 ? -33.435 19.411  -71.718  1.00 53.62  ? 242 PRO C CA    1 
ATOM   10023 C  C     . PRO C 1 242 ? -33.020 20.036  -73.040  1.00 54.22  ? 242 PRO C C     1 
ATOM   10024 O  O     . PRO C 1 242 ? -33.702 20.922  -73.550  1.00 54.20  ? 242 PRO C O     1 
ATOM   10025 C  CB    . PRO C 1 242 ? -34.251 18.132  -71.936  1.00 55.35  ? 242 PRO C CB    1 
ATOM   10026 C  CG    . PRO C 1 242 ? -35.672 18.461  -71.479  1.00 55.02  ? 242 PRO C CG    1 
ATOM   10027 C  CD    . PRO C 1 242 ? -35.729 19.935  -71.150  1.00 51.00  ? 242 PRO C CD    1 
ATOM   10028 N  N     . TYR C 1 243 ? -31.863 19.611  -73.554  1.00 54.66  ? 243 TYR C N     1 
ATOM   10029 C  CA    . TYR C 1 243 ? -31.307 20.200  -74.766  1.00 48.48  ? 243 TYR C CA    1 
ATOM   10030 C  C     . TYR C 1 243 ? -30.571 19.110  -75.532  1.00 51.69  ? 243 TYR C C     1 
ATOM   10031 O  O     . TYR C 1 243 ? -30.224 18.066  -74.957  1.00 50.85  ? 243 TYR C O     1 
ATOM   10032 C  CB    . TYR C 1 243 ? -30.461 21.438  -74.442  1.00 50.52  ? 243 TYR C CB    1 
ATOM   10033 C  CG    . TYR C 1 243 ? -29.261 21.202  -73.556  1.00 49.14  ? 243 TYR C CG    1 
ATOM   10034 C  CD1   . TYR C 1 243 ? -28.110 20.607  -74.051  1.00 52.66  ? 243 TYR C CD1   1 
ATOM   10035 C  CD2   . TYR C 1 243 ? -29.278 21.548  -72.217  1.00 49.74  ? 243 TYR C CD2   1 
ATOM   10036 C  CE1   . TYR C 1 243 ? -27.005 20.372  -73.246  1.00 49.29  ? 243 TYR C CE1   1 
ATOM   10037 C  CE2   . TYR C 1 243 ? -28.185 21.314  -71.394  1.00 45.48  ? 243 TYR C CE2   1 
ATOM   10038 C  CZ    . TYR C 1 243 ? -27.046 20.719  -71.910  1.00 46.02  ? 243 TYR C CZ    1 
ATOM   10039 O  OH    . TYR C 1 243 ? -25.948 20.468  -71.118  1.00 46.69  ? 243 TYR C OH    1 
ATOM   10040 N  N     . LEU C 1 244 ? -30.459 19.328  -76.855  1.00 52.24  ? 244 LEU C N     1 
ATOM   10041 C  CA    . LEU C 1 244 ? -29.718 18.451  -77.753  1.00 50.29  ? 244 LEU C CA    1 
ATOM   10042 C  C     . LEU C 1 244 ? -28.864 19.308  -78.672  1.00 47.64  ? 244 LEU C C     1 
ATOM   10043 O  O     . LEU C 1 244 ? -29.348 20.280  -79.264  1.00 51.39  ? 244 LEU C O     1 
ATOM   10044 C  CB    . LEU C 1 244 ? -30.672 17.578  -78.569  1.00 55.61  ? 244 LEU C CB    1 
ATOM   10045 C  CG    . LEU C 1 244 ? -30.063 16.819  -79.750  1.00 55.21  ? 244 LEU C CG    1 
ATOM   10046 C  CD1   . LEU C 1 244 ? -29.095 15.745  -79.297  1.00 60.13  ? 244 LEU C CD1   1 
ATOM   10047 C  CD2   . LEU C 1 244 ? -31.154 16.180  -80.591  1.00 56.29  ? 244 LEU C CD2   1 
ATOM   10048 N  N     . ILE C 1 245 ? -27.584 18.931  -78.751  1.00 46.44  ? 245 ILE C N     1 
ATOM   10049 C  CA    . ILE C 1 245 ? -26.615 19.601  -79.605  1.00 48.47  ? 245 ILE C CA    1 
ATOM   10050 C  C     . ILE C 1 245 ? -26.007 18.514  -80.477  1.00 46.81  ? 245 ILE C C     1 
ATOM   10051 O  O     . ILE C 1 245 ? -25.466 17.541  -79.964  1.00 42.04  ? 245 ILE C O     1 
ATOM   10052 C  CB    . ILE C 1 245 ? -25.550 20.359  -78.785  1.00 52.99  ? 245 ILE C CB    1 
ATOM   10053 C  CG1   . ILE C 1 245 ? -26.193 21.232  -77.701  1.00 50.91  ? 245 ILE C CG1   1 
ATOM   10054 C  CG2   . ILE C 1 245 ? -24.623 21.165  -79.691  1.00 52.97  ? 245 ILE C CG2   1 
ATOM   10055 C  CD1   . ILE C 1 245 ? -25.205 21.914  -76.797  1.00 50.00  ? 245 ILE C CD1   1 
ATOM   10056 N  N     . THR C 1 246 ? -26.162 18.678  -81.789  1.00 45.12  ? 246 THR C N     1 
ATOM   10057 C  CA    . THR C 1 246 ? -25.679 17.708  -82.757  1.00 48.93  ? 246 THR C CA    1 
ATOM   10058 C  C     . THR C 1 246 ? -24.472 18.286  -83.485  1.00 41.13  ? 246 THR C C     1 
ATOM   10059 O  O     . THR C 1 246 ? -24.383 19.497  -83.684  1.00 40.95  ? 246 THR C O     1 
ATOM   10060 C  CB    . THR C 1 246 ? -26.781 17.370  -83.769  1.00 48.20  ? 246 THR C CB    1 
ATOM   10061 O  OG1   . THR C 1 246 ? -27.172 18.635  -84.298  1.00 48.56  ? 246 THR C OG1   1 
ATOM   10062 C  CG2   . THR C 1 246 ? -27.977 16.683  -83.151  1.00 50.04  ? 246 THR C CG2   1 
ATOM   10063 N  N     . PHE C 1 247 ? -23.581 17.385  -83.900  1.00 44.15  ? 247 PHE C N     1 
ATOM   10064 C  CA    . PHE C 1 247 ? -22.362 17.734  -84.613  1.00 49.41  ? 247 PHE C CA    1 
ATOM   10065 C  C     . PHE C 1 247 ? -22.321 16.894  -85.887  1.00 46.76  ? 247 PHE C C     1 
ATOM   10066 O  O     . PHE C 1 247 ? -22.668 15.714  -85.852  1.00 53.16  ? 247 PHE C O     1 
ATOM   10067 C  CB    . PHE C 1 247 ? -21.137 17.498  -83.714  1.00 51.23  ? 247 PHE C CB    1 
ATOM   10068 C  CG    . PHE C 1 247 ? -21.239 18.193  -82.383  1.00 47.58  ? 247 PHE C CG    1 
ATOM   10069 C  CD1   . PHE C 1 247 ? -21.015 19.555  -82.279  1.00 47.30  ? 247 PHE C CD1   1 
ATOM   10070 C  CD2   . PHE C 1 247 ? -21.683 17.503  -81.260  1.00 49.41  ? 247 PHE C CD2   1 
ATOM   10071 C  CE1   . PHE C 1 247 ? -21.182 20.204  -81.062  1.00 47.41  ? 247 PHE C CE1   1 
ATOM   10072 C  CE2   . PHE C 1 247 ? -21.866 18.157  -80.050  1.00 45.50  ? 247 PHE C CE2   1 
ATOM   10073 C  CZ    . PHE C 1 247 ? -21.607 19.505  -79.952  1.00 47.70  ? 247 PHE C CZ    1 
ATOM   10074 N  N     . GLU C 1 248 ? -21.896 17.507  -86.997  1.00 52.02  ? 248 GLU C N     1 
ATOM   10075 C  CA    . GLU C 1 248 ? -22.010 16.896  -88.317  1.00 57.08  ? 248 GLU C CA    1 
ATOM   10076 C  C     . GLU C 1 248 ? -21.018 15.752  -88.494  1.00 57.40  ? 248 GLU C C     1 
ATOM   10077 O  O     . GLU C 1 248 ? -21.340 14.749  -89.126  1.00 55.39  ? 248 GLU C O     1 
ATOM   10078 C  CB    . GLU C 1 248 ? -21.650 17.879  -89.431  1.00 65.59  ? 248 GLU C CB    1 
ATOM   10079 C  CG    . GLU C 1 248 ? -22.541 19.093  -89.523  1.00 76.07  ? 248 GLU C CG    1 
ATOM   10080 C  CD    . GLU C 1 248 ? -23.827 18.911  -90.307  1.00 88.46  ? 248 GLU C CD    1 
ATOM   10081 O  OE1   . GLU C 1 248 ? -23.745 18.388  -91.430  1.00 102.49 ? 248 GLU C OE1   1 
ATOM   10082 O  OE2   . GLU C 1 248 ? -24.899 19.320  -89.806  1.00 94.90  ? 248 GLU C OE2   1 
ATOM   10083 N  N     . ASN C 1 249 ? -19.791 15.947  -88.000  1.00 52.31  ? 249 ASN C N     1 
ATOM   10084 C  CA    . ASN C 1 249 ? -18.654 15.159  -88.445  1.00 52.13  ? 249 ASN C CA    1 
ATOM   10085 C  C     . ASN C 1 249 ? -18.131 14.301  -87.314  1.00 52.53  ? 249 ASN C C     1 
ATOM   10086 O  O     . ASN C 1 249 ? -18.047 14.765  -86.181  1.00 49.11  ? 249 ASN C O     1 
ATOM   10087 C  CB    . ASN C 1 249 ? -17.513 16.047  -88.914  1.00 54.71  ? 249 ASN C CB    1 
ATOM   10088 C  CG    . ASN C 1 249 ? -18.016 17.047  -89.923  1.00 60.34  ? 249 ASN C CG    1 
ATOM   10089 O  OD1   . ASN C 1 249 ? -18.426 16.656  -91.010  1.00 56.26  ? 249 ASN C OD1   1 
ATOM   10090 N  ND2   . ASN C 1 249 ? -18.017 18.321  -89.569  1.00 57.80  ? 249 ASN C ND2   1 
ATOM   10091 N  N     . GLU C 1 250 ? -17.714 13.079  -87.661  1.00 50.97  ? 250 GLU C N     1 
ATOM   10092 C  CA    . GLU C 1 250 ? -17.288 12.127  -86.660  1.00 55.26  ? 250 GLU C CA    1 
ATOM   10093 C  C     . GLU C 1 250 ? -16.032 12.653  -85.957  1.00 54.53  ? 250 GLU C C     1 
ATOM   10094 O  O     . GLU C 1 250 ? -15.835 12.325  -84.793  1.00 53.17  ? 250 GLU C O     1 
ATOM   10095 C  CB    . GLU C 1 250 ? -17.185 10.722  -87.264  1.00 62.08  ? 250 GLU C CB    1 
ATOM   10096 C  CG    . GLU C 1 250 ? -16.051 10.503  -88.243  1.00 69.99  ? 250 GLU C CG    1 
ATOM   10097 C  CD    . GLU C 1 250 ? -16.025 9.100   -88.830  1.00 82.37  ? 250 GLU C CD    1 
ATOM   10098 O  OE1   . GLU C 1 250 ? -17.072 8.411   -88.757  1.00 74.89  ? 250 GLU C OE1   1 
ATOM   10099 O  OE2   . GLU C 1 250 ? -14.948 8.690   -89.337  1.00 83.49  ? 250 GLU C OE2   1 
ATOM   10100 N  N     . ASP C 1 251 ? -15.240 13.531  -86.607  1.00 51.47  ? 251 ASP C N     1 
ATOM   10101 C  CA    . ASP C 1 251 ? -14.038 14.086  -85.992  1.00 54.78  ? 251 ASP C CA    1 
ATOM   10102 C  C     . ASP C 1 251 ? -14.361 15.177  -84.976  1.00 52.60  ? 251 ASP C C     1 
ATOM   10103 O  O     . ASP C 1 251 ? -13.466 15.650  -84.270  1.00 52.10  ? 251 ASP C O     1 
ATOM   10104 C  CB    . ASP C 1 251 ? -13.102 14.709  -87.028  1.00 58.58  ? 251 ASP C CB    1 
ATOM   10105 C  CG    . ASP C 1 251 ? -12.430 13.687  -87.919  1.00 60.82  ? 251 ASP C CG    1 
ATOM   10106 O  OD1   . ASP C 1 251 ? -12.558 12.465  -87.649  1.00 63.90  ? 251 ASP C OD1   1 
ATOM   10107 O  OD2   . ASP C 1 251 ? -11.810 14.124  -88.889  1.00 71.40  ? 251 ASP C OD2   1 
ATOM   10108 N  N     . ASP C 1 252 ? -15.627 15.604  -84.939  1.00 46.73  ? 252 ASP C N     1 
ATOM   10109 C  CA    . ASP C 1 252 ? -16.043 16.690  -84.073  1.00 48.34  ? 252 ASP C CA    1 
ATOM   10110 C  C     . ASP C 1 252 ? -15.878 16.285  -82.607  1.00 40.08  ? 252 ASP C C     1 
ATOM   10111 O  O     . ASP C 1 252 ? -15.727 17.133  -81.745  1.00 47.67  ? 252 ASP C O     1 
ATOM   10112 C  CB    . ASP C 1 252 ? -17.488 17.115  -84.357  1.00 51.58  ? 252 ASP C CB    1 
ATOM   10113 C  CG    . ASP C 1 252 ? -17.709 17.856  -85.668  1.00 51.30  ? 252 ASP C CG    1 
ATOM   10114 O  OD1   . ASP C 1 252 ? -16.842 18.644  -86.051  1.00 50.22  ? 252 ASP C OD1   1 
ATOM   10115 O  OD2   . ASP C 1 252 ? -18.796 17.701  -86.246  1.00 54.95  ? 252 ASP C OD2   1 
ATOM   10116 N  N     . ILE C 1 253 ? -15.889 14.982  -82.326  1.00 43.52  ? 253 ILE C N     1 
ATOM   10117 C  CA    . ILE C 1 253 ? -15.871 14.522  -80.956  1.00 42.82  ? 253 ILE C CA    1 
ATOM   10118 C  C     . ILE C 1 253 ? -14.621 15.061  -80.269  1.00 48.08  ? 253 ILE C C     1 
ATOM   10119 O  O     . ILE C 1 253 ? -14.642 15.322  -79.071  1.00 47.83  ? 253 ILE C O     1 
ATOM   10120 C  CB    . ILE C 1 253 ? -16.003 12.989  -80.868  1.00 44.85  ? 253 ILE C CB    1 
ATOM   10121 C  CG1   . ILE C 1 253 ? -16.367 12.556  -79.451  1.00 50.58  ? 253 ILE C CG1   1 
ATOM   10122 C  CG2   . ILE C 1 253 ? -14.770 12.249  -81.373  1.00 47.85  ? 253 ILE C CG2   1 
ATOM   10123 C  CD1   . ILE C 1 253 ? -17.656 13.165  -78.949  1.00 54.79  ? 253 ILE C CD1   1 
ATOM   10124 N  N     . GLU C 1 254 ? -13.545 15.265  -81.037  1.00 48.86  ? 254 GLU C N     1 
ATOM   10125 C  CA    . GLU C 1 254 ? -12.307 15.742  -80.454  1.00 48.42  ? 254 GLU C CA    1 
ATOM   10126 C  C     . GLU C 1 254 ? -12.518 17.121  -79.840  1.00 41.36  ? 254 GLU C C     1 
ATOM   10127 O  O     . GLU C 1 254 ? -12.383 17.317  -78.632  1.00 39.56  ? 254 GLU C O     1 
ATOM   10128 C  CB    . GLU C 1 254 ? -11.188 15.758  -81.490  1.00 50.25  ? 254 GLU C CB    1 
ATOM   10129 C  CG    . GLU C 1 254 ? -9.913  16.346  -80.945  1.00 57.07  ? 254 GLU C CG    1 
ATOM   10130 C  CD    . GLU C 1 254 ? -8.668  15.915  -81.695  1.00 57.43  ? 254 GLU C CD    1 
ATOM   10131 O  OE1   . GLU C 1 254 ? -8.774  15.067  -82.587  1.00 66.00  ? 254 GLU C OE1   1 
ATOM   10132 O  OE2   . GLU C 1 254 ? -7.603  16.410  -81.352  1.00 52.28  ? 254 GLU C OE2   1 
ATOM   10133 N  N     . THR C 1 255 ? -12.826 18.104  -80.665  1.00 38.71  ? 255 THR C N     1 
ATOM   10134 C  CA    . THR C 1 255 ? -12.961 19.446  -80.127  1.00 39.94  ? 255 THR C CA    1 
ATOM   10135 C  C     . THR C 1 255 ? -14.160 19.520  -79.165  1.00 49.34  ? 255 THR C C     1 
ATOM   10136 O  O     . THR C 1 255 ? -14.201 20.386  -78.284  1.00 43.34  ? 255 THR C O     1 
ATOM   10137 C  CB    . THR C 1 255 ? -13.017 20.457  -81.272  1.00 43.75  ? 255 THR C CB    1 
ATOM   10138 O  OG1   . THR C 1 255 ? -12.939 21.762  -80.696  1.00 44.08  ? 255 THR C OG1   1 
ATOM   10139 C  CG2   . THR C 1 255 ? -14.275 20.337  -82.105  1.00 54.29  ? 255 THR C CG2   1 
ATOM   10140 N  N     . VAL C 1 256 ? -15.153 18.624  -79.312  1.00 44.40  ? 256 VAL C N     1 
ATOM   10141 C  CA    . VAL C 1 256 ? -16.348 18.723  -78.479  1.00 48.89  ? 256 VAL C CA    1 
ATOM   10142 C  C     . VAL C 1 256 ? -15.974 18.362  -77.045  1.00 43.85  ? 256 VAL C C     1 
ATOM   10143 O  O     . VAL C 1 256 ? -16.368 19.035  -76.096  1.00 41.18  ? 256 VAL C O     1 
ATOM   10144 C  CB    . VAL C 1 256 ? -17.520 17.862  -78.997  1.00 49.24  ? 256 VAL C CB    1 
ATOM   10145 C  CG1   . VAL C 1 256 ? -18.575 17.636  -77.928  1.00 54.78  ? 256 VAL C CG1   1 
ATOM   10146 C  CG2   . VAL C 1 256 ? -18.165 18.468  -80.236  1.00 52.43  ? 256 VAL C CG2   1 
ATOM   10147 N  N     . THR C 1 257 ? -15.174 17.307  -76.922  1.00 44.38  ? 257 THR C N     1 
ATOM   10148 C  CA    . THR C 1 257 ? -14.718 16.839  -75.634  1.00 43.76  ? 257 THR C CA    1 
ATOM   10149 C  C     . THR C 1 257 ? -13.821 17.868  -74.951  1.00 43.97  ? 257 THR C C     1 
ATOM   10150 O  O     . THR C 1 257 ? -13.865 17.973  -73.730  1.00 42.52  ? 257 THR C O     1 
ATOM   10151 C  CB    . THR C 1 257 ? -14.030 15.484  -75.782  1.00 48.55  ? 257 THR C CB    1 
ATOM   10152 O  OG1   . THR C 1 257 ? -15.013 14.652  -76.404  1.00 44.78  ? 257 THR C OG1   1 
ATOM   10153 C  CG2   . THR C 1 257 ? -13.569 14.910  -74.455  1.00 44.52  ? 257 THR C CG2   1 
ATOM   10154 N  N     . GLU C 1 258 ? -13.032 18.633  -75.727  1.00 49.46  ? 258 GLU C N     1 
ATOM   10155 C  CA    . GLU C 1 258 ? -12.201 19.693  -75.168  1.00 44.22  ? 258 GLU C CA    1 
ATOM   10156 C  C     . GLU C 1 258 ? -13.097 20.738  -74.514  1.00 46.78  ? 258 GLU C C     1 
ATOM   10157 O  O     . GLU C 1 258 ? -12.753 21.280  -73.465  1.00 50.52  ? 258 GLU C O     1 
ATOM   10158 C  CB    . GLU C 1 258 ? -11.282 20.352  -76.202  1.00 42.28  ? 258 GLU C CB    1 
ATOM   10159 C  CG    . GLU C 1 258 ? -10.131 19.452  -76.642  1.00 47.47  ? 258 GLU C CG    1 
ATOM   10160 C  CD    . GLU C 1 258 ? -9.195  19.057  -75.509  1.00 46.64  ? 258 GLU C CD    1 
ATOM   10161 O  OE1   . GLU C 1 258 ? -8.524  19.951  -74.990  1.00 48.65  ? 258 GLU C OE1   1 
ATOM   10162 O  OE2   . GLU C 1 258 ? -9.194  17.882  -75.106  1.00 48.43  ? 258 GLU C OE2   1 
ATOM   10163 N  N     . ARG C 1 259 ? -14.231 21.033  -75.151  1.00 44.84  ? 259 ARG C N     1 
ATOM   10164 C  CA    . ARG C 1 259 ? -15.087 22.115  -74.697  1.00 45.72  ? 259 ARG C CA    1 
ATOM   10165 C  C     . ARG C 1 259 ? -15.909 21.650  -73.497  1.00 41.58  ? 259 ARG C C     1 
ATOM   10166 O  O     . ARG C 1 259 ? -16.308 22.458  -72.670  1.00 43.54  ? 259 ARG C O     1 
ATOM   10167 C  CB    . ARG C 1 259 ? -15.950 22.582  -75.871  1.00 48.01  ? 259 ARG C CB    1 
ATOM   10168 C  CG    . ARG C 1 259 ? -15.111 23.148  -77.003  1.00 53.89  ? 259 ARG C CG    1 
ATOM   10169 C  CD    . ARG C 1 259 ? -15.738 22.851  -78.345  1.00 59.54  ? 259 ARG C CD    1 
ATOM   10170 N  NE    . ARG C 1 259 ? -14.901 23.341  -79.421  1.00 58.77  ? 259 ARG C NE    1 
ATOM   10171 C  CZ    . ARG C 1 259 ? -15.111 24.473  -80.084  1.00 63.41  ? 259 ARG C CZ    1 
ATOM   10172 N  NH1   . ARG C 1 259 ? -16.065 25.309  -79.712  1.00 58.92  ? 259 ARG C NH1   1 
ATOM   10173 N  NH2   . ARG C 1 259 ? -14.347 24.771  -81.117  1.00 63.49  ? 259 ARG C NH2   1 
ATOM   10174 N  N     . LEU C 1 260 ? -16.142 20.341  -73.399  1.00 41.14  ? 260 LEU C N     1 
ATOM   10175 C  CA    . LEU C 1 260 ? -16.973 19.805  -72.336  1.00 39.13  ? 260 LEU C CA    1 
ATOM   10176 C  C     . LEU C 1 260 ? -16.200 19.812  -71.023  1.00 40.11  ? 260 LEU C C     1 
ATOM   10177 O  O     . LEU C 1 260 ? -16.825 19.930  -69.977  1.00 42.50  ? 260 LEU C O     1 
ATOM   10178 C  CB    . LEU C 1 260 ? -17.410 18.389  -72.699  1.00 36.40  ? 260 LEU C CB    1 
ATOM   10179 C  CG    . LEU C 1 260 ? -18.538 18.249  -73.727  1.00 38.48  ? 260 LEU C CG    1 
ATOM   10180 C  CD1   . LEU C 1 260 ? -18.725 16.784  -74.080  1.00 38.76  ? 260 LEU C CD1   1 
ATOM   10181 C  CD2   . LEU C 1 260 ? -19.856 18.807  -73.228  1.00 40.43  ? 260 LEU C CD2   1 
ATOM   10182 N  N     . ARG C 1 261 ? -14.866 19.646  -71.084  1.00 39.83  ? 261 ARG C N     1 
ATOM   10183 C  CA    . ARG C 1 261 ? -14.049 19.453  -69.890  1.00 39.11  ? 261 ARG C CA    1 
ATOM   10184 C  C     . ARG C 1 261 ? -14.273 20.594  -68.899  1.00 35.39  ? 261 ARG C C     1 
ATOM   10185 O  O     . ARG C 1 261 ? -14.733 20.365  -67.785  1.00 40.95  ? 261 ARG C O     1 
ATOM   10186 C  CB    . ARG C 1 261 ? -12.560 19.280  -70.226  1.00 41.46  ? 261 ARG C CB    1 
ATOM   10187 C  CG    . ARG C 1 261 ? -11.681 19.128  -68.986  1.00 39.89  ? 261 ARG C CG    1 
ATOM   10188 C  CD    . ARG C 1 261 ? -10.226 18.863  -69.309  1.00 39.66  ? 261 ARG C CD    1 
ATOM   10189 N  NE    . ARG C 1 261 ? -9.685  19.872  -70.190  1.00 37.52  ? 261 ARG C NE    1 
ATOM   10190 C  CZ    . ARG C 1 261 ? -9.415  19.689  -71.477  1.00 43.65  ? 261 ARG C CZ    1 
ATOM   10191 N  NH1   . ARG C 1 261 ? -9.506  18.487  -72.031  1.00 42.85  ? 261 ARG C NH1   1 
ATOM   10192 N  NH2   . ARG C 1 261 ? -9.052  20.722  -72.213  1.00 42.83  ? 261 ARG C NH2   1 
ATOM   10193 N  N     . PRO C 1 262 ? -14.006 21.870  -69.243  1.00 36.75  ? 262 PRO C N     1 
ATOM   10194 C  CA    . PRO C 1 262 ? -14.151 22.938  -68.263  1.00 37.56  ? 262 PRO C CA    1 
ATOM   10195 C  C     . PRO C 1 262 ? -15.607 23.099  -67.852  1.00 38.21  ? 262 PRO C C     1 
ATOM   10196 O  O     . PRO C 1 262 ? -15.877 23.441  -66.705  1.00 43.07  ? 262 PRO C O     1 
ATOM   10197 C  CB    . PRO C 1 262 ? -13.585 24.199  -68.938  1.00 36.00  ? 262 PRO C CB    1 
ATOM   10198 C  CG    . PRO C 1 262 ? -13.618 23.878  -70.431  1.00 35.06  ? 262 PRO C CG    1 
ATOM   10199 C  CD    . PRO C 1 262 ? -13.577 22.366  -70.558  1.00 37.45  ? 262 PRO C CD    1 
ATOM   10200 N  N     . LEU C 1 263 ? -16.558 22.833  -68.764  1.00 40.19  ? 263 LEU C N     1 
ATOM   10201 C  CA    . LEU C 1 263 ? -17.960 23.014  -68.405  1.00 38.94  ? 263 LEU C CA    1 
ATOM   10202 C  C     . LEU C 1 263 ? -18.339 22.028  -67.302  1.00 37.98  ? 263 LEU C C     1 
ATOM   10203 O  O     . LEU C 1 263 ? -19.054 22.378  -66.357  1.00 38.36  ? 263 LEU C O     1 
ATOM   10204 C  CB    . LEU C 1 263 ? -18.854 22.809  -69.629  1.00 39.29  ? 263 LEU C CB    1 
ATOM   10205 C  CG    . LEU C 1 263 ? -18.788 23.926  -70.675  1.00 45.01  ? 263 LEU C CG    1 
ATOM   10206 C  CD1   . LEU C 1 263 ? -19.577 23.543  -71.935  1.00 45.09  ? 263 LEU C CD1   1 
ATOM   10207 C  CD2   . LEU C 1 263 ? -19.297 25.241  -70.121  1.00 43.81  ? 263 LEU C CD2   1 
ATOM   10208 N  N     . LYS C 1 264 ? -17.896 20.782  -67.462  1.00 36.28  ? 264 LYS C N     1 
ATOM   10209 C  CA    . LYS C 1 264 ? -18.207 19.746  -66.501  1.00 38.54  ? 264 LYS C CA    1 
ATOM   10210 C  C     . LYS C 1 264 ? -17.416 19.948  -65.212  1.00 43.77  ? 264 LYS C C     1 
ATOM   10211 O  O     . LYS C 1 264 ? -17.974 19.821  -64.124  1.00 44.82  ? 264 LYS C O     1 
ATOM   10212 C  CB    . LYS C 1 264 ? -17.896 18.365  -67.074  1.00 41.11  ? 264 LYS C CB    1 
ATOM   10213 C  CG    . LYS C 1 264 ? -18.475 17.214  -66.258  1.00 50.83  ? 264 LYS C CG    1 
ATOM   10214 C  CD    . LYS C 1 264 ? -20.012 17.201  -66.204  1.00 47.54  ? 264 LYS C CD    1 
ATOM   10215 C  CE    . LYS C 1 264 ? -20.564 16.282  -65.136  1.00 51.06  ? 264 LYS C CE    1 
ATOM   10216 N  NZ    . LYS C 1 264 ? -21.936 16.661  -64.745  1.00 55.01  ? 264 LYS C NZ    1 
ATOM   10217 N  N     . VAL C 1 265 ? -16.111 20.233  -65.337  1.00 47.12  ? 265 VAL C N     1 
ATOM   10218 C  CA    . VAL C 1 265 ? -15.270 20.323  -64.161  1.00 44.55  ? 265 VAL C CA    1 
ATOM   10219 C  C     . VAL C 1 265 ? -15.825 21.410  -63.257  1.00 45.25  ? 265 VAL C C     1 
ATOM   10220 O  O     . VAL C 1 265 ? -15.930 21.163  -62.063  1.00 46.03  ? 265 VAL C O     1 
ATOM   10221 C  CB    . VAL C 1 265 ? -13.785 20.529  -64.506  1.00 48.07  ? 265 VAL C CB    1 
ATOM   10222 C  CG1   . VAL C 1 265 ? -12.966 20.876  -63.272  1.00 50.68  ? 265 VAL C CG1   1 
ATOM   10223 C  CG2   . VAL C 1 265 ? -13.217 19.294  -65.190  1.00 43.83  ? 265 VAL C CG2   1 
ATOM   10224 N  N     . ALA C 1 266 ? -16.261 22.540  -63.843  1.00 42.98  ? 266 ALA C N     1 
ATOM   10225 C  CA    . ALA C 1 266 ? -16.762 23.673  -63.085  1.00 45.41  ? 266 ALA C CA    1 
ATOM   10226 C  C     . ALA C 1 266 ? -18.213 23.459  -62.663  1.00 47.65  ? 266 ALA C C     1 
ATOM   10227 O  O     . ALA C 1 266 ? -18.766 24.305  -61.975  1.00 50.73  ? 266 ALA C O     1 
ATOM   10228 C  CB    . ALA C 1 266 ? -16.647 24.946  -63.891  1.00 46.40  ? 266 ALA C CB    1 
ATOM   10229 N  N     . GLY C 1 267 ? -18.839 22.361  -63.097  1.00 48.88  ? 267 GLY C N     1 
ATOM   10230 C  CA    . GLY C 1 267 ? -20.234 22.090  -62.770  1.00 50.18  ? 267 GLY C CA    1 
ATOM   10231 C  C     . GLY C 1 267 ? -21.267 22.891  -63.571  1.00 48.18  ? 267 GLY C C     1 
ATOM   10232 O  O     . GLY C 1 267 ? -22.439 22.933  -63.193  1.00 48.71  ? 267 GLY C O     1 
ATOM   10233 N  N     . VAL C 1 268 ? -20.877 23.463  -64.716  1.00 51.57  ? 268 VAL C N     1 
ATOM   10234 C  CA    . VAL C 1 268 ? -21.811 24.225  -65.529  1.00 48.13  ? 268 VAL C CA    1 
ATOM   10235 C  C     . VAL C 1 268 ? -22.814 23.281  -66.194  1.00 41.88  ? 268 VAL C C     1 
ATOM   10236 O  O     . VAL C 1 268 ? -23.994 23.600  -66.292  1.00 43.01  ? 268 VAL C O     1 
ATOM   10237 C  CB    . VAL C 1 268 ? -21.084 25.108  -66.556  1.00 48.87  ? 268 VAL C CB    1 
ATOM   10238 C  CG1   . VAL C 1 268 ? -22.060 25.749  -67.524  1.00 48.17  ? 268 VAL C CG1   1 
ATOM   10239 C  CG2   . VAL C 1 268 ? -20.239 26.170  -65.872  1.00 47.31  ? 268 VAL C CG2   1 
ATOM   10240 N  N     . ILE C 1 269 ? -22.333 22.151  -66.703  1.00 40.57  ? 269 ILE C N     1 
ATOM   10241 C  CA    . ILE C 1 269 ? -23.201 21.023  -67.027  1.00 39.36  ? 269 ILE C CA    1 
ATOM   10242 C  C     . ILE C 1 269 ? -23.500 20.308  -65.710  1.00 39.61  ? 269 ILE C C     1 
ATOM   10243 O  O     . ILE C 1 269 ? -22.584 19.772  -65.073  1.00 33.53  ? 269 ILE C O     1 
ATOM   10244 C  CB    . ILE C 1 269 ? -22.491 20.088  -68.025  1.00 41.71  ? 269 ILE C CB    1 
ATOM   10245 C  CG1   . ILE C 1 269 ? -22.250 20.774  -69.367  1.00 46.76  ? 269 ILE C CG1   1 
ATOM   10246 C  CG2   . ILE C 1 269 ? -23.232 18.770  -68.185  1.00 46.34  ? 269 ILE C CG2   1 
ATOM   10247 C  CD1   . ILE C 1 269 ? -21.234 20.068  -70.217  1.00 46.98  ? 269 ILE C CD1   1 
ATOM   10248 N  N     . GLN C 1 270 ? -24.767 20.287  -65.292  1.00 38.75  ? 270 GLN C N     1 
ATOM   10249 C  CA    . GLN C 1 270 ? -25.110 19.880  -63.932  1.00 38.88  ? 270 GLN C CA    1 
ATOM   10250 C  C     . GLN C 1 270 ? -25.335 18.372  -63.827  1.00 41.33  ? 270 GLN C C     1 
ATOM   10251 O  O     . GLN C 1 270 ? -25.360 17.819  -62.729  1.00 43.71  ? 270 GLN C O     1 
ATOM   10252 C  CB    . GLN C 1 270 ? -26.356 20.621  -63.452  1.00 40.17  ? 270 GLN C CB    1 
ATOM   10253 C  CG    . GLN C 1 270 ? -26.200 22.131  -63.427  1.00 40.37  ? 270 GLN C CG    1 
ATOM   10254 C  CD    . GLN C 1 270 ? -27.565 22.771  -63.564  1.00 45.47  ? 270 GLN C CD    1 
ATOM   10255 O  OE1   . GLN C 1 270 ? -28.139 22.809  -64.653  1.00 43.32  ? 270 GLN C OE1   1 
ATOM   10256 N  NE2   . GLN C 1 270 ? -28.107 23.263  -62.457  1.00 42.75  ? 270 GLN C NE2   1 
ATOM   10257 N  N     . ASN C 1 271 ? -25.490 17.682  -64.955  1.00 39.70  ? 271 ASN C N     1 
ATOM   10258 C  CA    . ASN C 1 271 ? -25.911 16.292  -64.898  1.00 42.43  ? 271 ASN C CA    1 
ATOM   10259 C  C     . ASN C 1 271 ? -24.878 15.444  -65.610  1.00 42.68  ? 271 ASN C C     1 
ATOM   10260 O  O     . ASN C 1 271 ? -23.960 15.978  -66.214  1.00 44.03  ? 271 ASN C O     1 
ATOM   10261 C  CB    . ASN C 1 271 ? -27.321 16.066  -65.480  1.00 43.09  ? 271 ASN C CB    1 
ATOM   10262 C  CG    . ASN C 1 271 ? -27.473 16.392  -66.954  1.00 43.38  ? 271 ASN C CG    1 
ATOM   10263 O  OD1   . ASN C 1 271 ? -26.868 17.333  -67.449  1.00 43.69  ? 271 ASN C OD1   1 
ATOM   10264 N  ND2   . ASN C 1 271 ? -28.297 15.637  -67.668  1.00 48.59  ? 271 ASN C ND2   1 
ATOM   10265 N  N     . GLY C 1 272 ? -25.057 14.126  -65.490  1.00 47.49  ? 272 GLY C N     1 
ATOM   10266 C  CA    . GLY C 1 272 ? -24.363 13.170  -66.320  1.00 43.74  ? 272 GLY C CA    1 
ATOM   10267 C  C     . GLY C 1 272 ? -25.027 13.175  -67.688  1.00 51.90  ? 272 GLY C C     1 
ATOM   10268 O  O     . GLY C 1 272 ? -25.871 12.324  -67.996  1.00 51.25  ? 272 GLY C O     1 
ATOM   10269 N  N     . ALA C 1 273 ? -24.706 14.229  -68.436  1.00 45.58  ? 273 ALA C N     1 
ATOM   10270 C  CA    . ALA C 1 273 ? -25.113 14.354  -69.813  1.00 56.20  ? 273 ALA C CA    1 
ATOM   10271 C  C     . ALA C 1 273 ? -24.293 13.369  -70.647  1.00 65.70  ? 273 ALA C C     1 
ATOM   10272 O  O     . ALA C 1 273 ? -23.308 12.805  -70.152  1.00 60.39  ? 273 ALA C O     1 
ATOM   10273 C  CB    . ALA C 1 273 ? -24.923 15.782  -70.250  1.00 56.18  ? 273 ALA C CB    1 
ATOM   10274 N  N     . THR C 1 274 ? -24.710 13.186  -71.908  1.00 53.83  ? 274 THR C N     1 
ATOM   10275 C  CA    . THR C 1 274 ? -24.205 12.109  -72.749  1.00 52.11  ? 274 THR C CA    1 
ATOM   10276 C  C     . THR C 1 274 ? -23.874 12.660  -74.133  1.00 45.25  ? 274 THR C C     1 
ATOM   10277 O  O     . THR C 1 274 ? -24.471 13.641  -74.557  1.00 45.01  ? 274 THR C O     1 
ATOM   10278 C  CB    . THR C 1 274 ? -25.246 10.988  -72.800  1.00 52.45  ? 274 THR C CB    1 
ATOM   10279 O  OG1   . THR C 1 274 ? -26.506 11.589  -73.107  1.00 54.88  ? 274 THR C OG1   1 
ATOM   10280 C  CG2   . THR C 1 274 ? -25.367 10.248  -71.492  1.00 52.33  ? 274 THR C CG2   1 
ATOM   10281 N  N     . VAL C 1 275 ? -22.864 12.080  -74.785  1.00 50.19  ? 275 VAL C N     1 
ATOM   10282 C  CA    . VAL C 1 275 ? -22.591 12.343  -76.184  1.00 52.26  ? 275 VAL C CA    1 
ATOM   10283 C  C     . VAL C 1 275 ? -22.683 11.008  -76.926  1.00 55.38  ? 275 VAL C C     1 
ATOM   10284 O  O     . VAL C 1 275 ? -21.847 10.134  -76.730  1.00 55.81  ? 275 VAL C O     1 
ATOM   10285 C  CB    . VAL C 1 275 ? -21.226 13.022  -76.382  1.00 55.26  ? 275 VAL C CB    1 
ATOM   10286 C  CG1   . VAL C 1 275 ? -20.978 13.383  -77.844  1.00 54.23  ? 275 VAL C CG1   1 
ATOM   10287 C  CG2   . VAL C 1 275 ? -21.086 14.253  -75.505  1.00 52.25  ? 275 VAL C CG2   1 
ATOM   10288 N  N     . ARG C 1 276 ? -23.723 10.846  -77.754  1.00 50.10  ? 276 ARG C N     1 
ATOM   10289 C  CA    . ARG C 1 276 ? -24.057 9.553   -78.335  1.00 54.50  ? 276 ARG C CA    1 
ATOM   10290 C  C     . ARG C 1 276 ? -23.800 9.569   -79.846  1.00 45.28  ? 276 ARG C C     1 
ATOM   10291 O  O     . ARG C 1 276 ? -23.933 10.611  -80.477  1.00 45.56  ? 276 ARG C O     1 
ATOM   10292 C  CB    . ARG C 1 276 ? -25.489 9.205   -77.910  1.00 59.73  ? 276 ARG C CB    1 
ATOM   10293 C  CG    . ARG C 1 276 ? -25.561 8.624   -76.504  1.00 66.52  ? 276 ARG C CG    1 
ATOM   10294 C  CD    . ARG C 1 276 ? -26.835 8.880   -75.714  1.00 74.50  ? 276 ARG C CD    1 
ATOM   10295 N  NE    . ARG C 1 276 ? -28.028 8.445   -76.413  1.00 71.18  ? 276 ARG C NE    1 
ATOM   10296 C  CZ    . ARG C 1 276 ? -28.690 7.320   -76.173  1.00 71.30  ? 276 ARG C CZ    1 
ATOM   10297 N  NH1   . ARG C 1 276 ? -28.227 6.435   -75.308  1.00 68.57  ? 276 ARG C NH1   1 
ATOM   10298 N  NH2   . ARG C 1 276 ? -29.807 7.070   -76.835  1.00 73.79  ? 276 ARG C NH2   1 
ATOM   10299 N  N     . SER C 1 277 ? -23.353 8.414   -80.381  1.00 50.63  ? 277 SER C N     1 
ATOM   10300 C  CA    . SER C 1 277 ? -23.054 8.224   -81.797  1.00 49.75  ? 277 SER C CA    1 
ATOM   10301 C  C     . SER C 1 277 ? -24.341 8.024   -82.586  1.00 44.25  ? 277 SER C C     1 
ATOM   10302 O  O     . SER C 1 277 ? -25.358 7.591   -82.051  1.00 50.21  ? 277 SER C O     1 
ATOM   10303 C  CB    . SER C 1 277 ? -22.130 7.051   -82.054  1.00 47.26  ? 277 SER C CB    1 
ATOM   10304 O  OG    . SER C 1 277 ? -22.771 5.822   -81.742  1.00 45.27  ? 277 SER C OG    1 
ATOM   10305 N  N     . LEU C 1 278 ? -24.257 8.311   -83.875  1.00 47.31  ? 278 LEU C N     1 
ATOM   10306 C  CA    . LEU C 1 278 ? -25.423 8.355   -84.744  1.00 51.60  ? 278 LEU C CA    1 
ATOM   10307 C  C     . LEU C 1 278 ? -26.286 7.102   -84.611  1.00 49.67  ? 278 LEU C C     1 
ATOM   10308 O  O     . LEU C 1 278 ? -27.491 7.201   -84.377  1.00 52.73  ? 278 LEU C O     1 
ATOM   10309 C  CB    . LEU C 1 278 ? -24.940 8.505   -86.184  1.00 48.31  ? 278 LEU C CB    1 
ATOM   10310 C  CG    . LEU C 1 278 ? -26.027 8.333   -87.242  1.00 54.95  ? 278 LEU C CG    1 
ATOM   10311 C  CD1   . LEU C 1 278 ? -27.098 9.411   -87.102  1.00 52.15  ? 278 LEU C CD1   1 
ATOM   10312 C  CD2   . LEU C 1 278 ? -25.408 8.368   -88.630  1.00 51.89  ? 278 LEU C CD2   1 
ATOM   10313 N  N     . VAL C 1 279 ? -25.670 5.931   -84.814  1.00 46.04  ? 279 VAL C N     1 
ATOM   10314 C  CA    . VAL C 1 279 ? -26.415 4.691   -84.908  1.00 43.98  ? 279 VAL C CA    1 
ATOM   10315 C  C     . VAL C 1 279 ? -27.106 4.388   -83.583  1.00 56.57  ? 279 VAL C C     1 
ATOM   10316 O  O     . VAL C 1 279 ? -28.236 3.910   -83.582  1.00 56.19  ? 279 VAL C O     1 
ATOM   10317 C  CB    . VAL C 1 279 ? -25.536 3.516   -85.361  1.00 47.39  ? 279 VAL C CB    1 
ATOM   10318 C  CG1   . VAL C 1 279 ? -26.333 2.219   -85.461  1.00 51.55  ? 279 VAL C CG1   1 
ATOM   10319 C  CG2   . VAL C 1 279 ? -24.844 3.820   -86.666  1.00 45.48  ? 279 VAL C CG2   1 
ATOM   10320 N  N     . LEU C 1 280 ? -26.439 4.642   -82.450  1.00 62.73  ? 280 LEU C N     1 
ATOM   10321 C  CA    . LEU C 1 280 ? -27.075 4.432   -81.157  1.00 61.25  ? 280 LEU C CA    1 
ATOM   10322 C  C     . LEU C 1 280 ? -28.331 5.306   -81.017  1.00 56.60  ? 280 LEU C C     1 
ATOM   10323 O  O     . LEU C 1 280 ? -29.368 4.830   -80.557  1.00 50.35  ? 280 LEU C O     1 
ATOM   10324 C  CB    . LEU C 1 280 ? -26.066 4.714   -80.039  1.00 64.12  ? 280 LEU C CB    1 
ATOM   10325 C  CG    . LEU C 1 280 ? -26.599 4.551   -78.614  1.00 64.50  ? 280 LEU C CG    1 
ATOM   10326 C  CD1   . LEU C 1 280 ? -27.072 3.130   -78.364  1.00 59.81  ? 280 LEU C CD1   1 
ATOM   10327 C  CD2   . LEU C 1 280 ? -25.543 4.947   -77.587  1.00 70.54  ? 280 LEU C CD2   1 
ATOM   10328 N  N     . ASP C 1 281 ? -28.245 6.587   -81.398  1.00 48.44  ? 281 ASP C N     1 
ATOM   10329 C  CA    . ASP C 1 281 ? -29.391 7.475   -81.283  1.00 54.19  ? 281 ASP C CA    1 
ATOM   10330 C  C     . ASP C 1 281 ? -30.475 7.053   -82.280  1.00 55.00  ? 281 ASP C C     1 
ATOM   10331 O  O     . ASP C 1 281 ? -31.653 7.022   -81.939  1.00 57.37  ? 281 ASP C O     1 
ATOM   10332 C  CB    . ASP C 1 281 ? -28.959 8.942   -81.387  1.00 59.73  ? 281 ASP C CB    1 
ATOM   10333 C  CG    . ASP C 1 281 ? -28.437 9.518   -80.070  1.00 74.45  ? 281 ASP C CG    1 
ATOM   10334 O  OD1   . ASP C 1 281 ? -28.531 8.812   -79.032  1.00 70.92  ? 281 ASP C OD1   1 
ATOM   10335 O  OD2   . ASP C 1 281 ? -27.934 10.669  -80.076  1.00 80.96  ? 281 ASP C OD2   1 
ATOM   10336 N  N     . ALA C 1 282 ? -30.064 6.679   -83.493  1.00 52.86  ? 282 ALA C N     1 
ATOM   10337 C  CA    . ALA C 1 282 ? -31.000 6.300   -84.534  1.00 50.97  ? 282 ALA C CA    1 
ATOM   10338 C  C     . ALA C 1 282 ? -31.747 5.026   -84.160  1.00 49.29  ? 282 ALA C C     1 
ATOM   10339 O  O     . ALA C 1 282 ? -32.940 4.921   -84.435  1.00 52.11  ? 282 ALA C O     1 
ATOM   10340 C  CB    . ALA C 1 282 ? -30.281 6.135   -85.843  1.00 48.31  ? 282 ALA C CB    1 
ATOM   10341 N  N     . ALA C 1 283 ? -31.053 4.076   -83.522  1.00 45.39  ? 283 ALA C N     1 
ATOM   10342 C  CA    . ALA C 1 283 ? -31.630 2.775   -83.215  1.00 49.93  ? 283 ALA C CA    1 
ATOM   10343 C  C     . ALA C 1 283 ? -32.754 2.859   -82.181  1.00 55.69  ? 283 ALA C C     1 
ATOM   10344 O  O     . ALA C 1 283 ? -33.347 1.826   -81.849  1.00 53.03  ? 283 ALA C O     1 
ATOM   10345 C  CB    . ALA C 1 283 ? -30.578 1.807   -82.734  1.00 50.26  ? 283 ALA C CB    1 
ATOM   10346 N  N     . ILE C 1 284 ? -33.025 4.060   -81.654  1.00 57.26  ? 284 ILE C N     1 
ATOM   10347 C  CA    . ILE C 1 284 ? -34.085 4.211   -80.674  1.00 61.36  ? 284 ILE C CA    1 
ATOM   10348 C  C     . ILE C 1 284 ? -35.424 4.295   -81.398  1.00 60.43  ? 284 ILE C C     1 
ATOM   10349 O  O     . ILE C 1 284 ? -36.442 3.926   -80.826  1.00 66.55  ? 284 ILE C O     1 
ATOM   10350 C  CB    . ILE C 1 284 ? -33.853 5.440   -79.773  1.00 65.03  ? 284 ILE C CB    1 
ATOM   10351 C  CG1   . ILE C 1 284 ? -32.474 5.412   -79.101  1.00 60.84  ? 284 ILE C CG1   1 
ATOM   10352 C  CG2   . ILE C 1 284 ? -34.970 5.560   -78.748  1.00 62.38  ? 284 ILE C CG2   1 
ATOM   10353 C  CD1   . ILE C 1 284 ? -32.265 4.219   -78.206  1.00 60.17  ? 284 ILE C CD1   1 
ATOM   10354 N  N     . THR C 1 285 ? -35.405 4.807   -82.634  1.00 65.36  ? 285 THR C N     1 
ATOM   10355 C  CA    . THR C 1 285 ? -36.615 5.091   -83.389  1.00 63.88  ? 285 THR C CA    1 
ATOM   10356 C  C     . THR C 1 285 ? -36.530 4.582   -84.831  1.00 64.12  ? 285 THR C C     1 
ATOM   10357 O  O     . THR C 1 285 ? -37.374 4.953   -85.651  1.00 70.34  ? 285 THR C O     1 
ATOM   10358 C  CB    . THR C 1 285 ? -36.887 6.600   -83.379  1.00 60.51  ? 285 THR C CB    1 
ATOM   10359 O  OG1   . THR C 1 285 ? -35.973 7.220   -84.279  1.00 64.23  ? 285 THR C OG1   1 
ATOM   10360 C  CG2   . THR C 1 285 ? -36.754 7.213   -82.003  1.00 63.68  ? 285 THR C CG2   1 
ATOM   10361 N  N     . ARG C 1 286 ? -35.523 3.742   -85.134  1.00 57.69  ? 286 ARG C N     1 
ATOM   10362 C  CA    . ARG C 1 286 ? -35.323 3.189   -86.465  1.00 57.26  ? 286 ARG C CA    1 
ATOM   10363 C  C     . ARG C 1 286 ? -34.604 1.839   -86.392  1.00 59.36  ? 286 ARG C C     1 
ATOM   10364 O  O     . ARG C 1 286 ? -33.955 1.517   -85.401  1.00 67.06  ? 286 ARG C O     1 
ATOM   10365 C  CB    . ARG C 1 286 ? -34.490 4.126   -87.337  1.00 59.36  ? 286 ARG C CB    1 
ATOM   10366 C  CG    . ARG C 1 286 ? -35.156 5.439   -87.711  1.00 63.68  ? 286 ARG C CG    1 
ATOM   10367 C  CD    . ARG C 1 286 ? -36.327 5.276   -88.667  1.00 67.16  ? 286 ARG C CD    1 
ATOM   10368 N  NE    . ARG C 1 286 ? -36.641 6.556   -89.306  1.00 69.21  ? 286 ARG C NE    1 
ATOM   10369 C  CZ    . ARG C 1 286 ? -37.207 7.595   -88.700  1.00 56.61  ? 286 ARG C CZ    1 
ATOM   10370 N  NH1   . ARG C 1 286 ? -37.643 7.473   -87.458  1.00 48.92  ? 286 ARG C NH1   1 
ATOM   10371 N  NH2   . ARG C 1 286 ? -37.359 8.743   -89.353  1.00 53.36  ? 286 ARG C NH2   1 
ATOM   10372 N  N     . THR C 1 287 ? -34.753 1.040   -87.455  1.00 54.93  ? 287 THR C N     1 
ATOM   10373 C  CA    . THR C 1 287 ? -33.980 -0.177  -87.636  1.00 61.28  ? 287 THR C CA    1 
ATOM   10374 C  C     . THR C 1 287 ? -33.163 -0.002  -88.917  1.00 60.04  ? 287 THR C C     1 
ATOM   10375 O  O     . THR C 1 287 ? -33.521 0.814   -89.762  1.00 57.40  ? 287 THR C O     1 
ATOM   10376 C  CB    . THR C 1 287 ? -34.872 -1.432  -87.597  1.00 61.07  ? 287 THR C CB    1 
ATOM   10377 O  OG1   . THR C 1 287 ? -35.643 -1.525  -88.799  1.00 57.77  ? 287 THR C OG1   1 
ATOM   10378 C  CG2   . THR C 1 287 ? -35.793 -1.454  -86.394  1.00 59.52  ? 287 THR C CG2   1 
ATOM   10379 N  N     . LYS C 1 288 ? -32.046 -0.747  -89.014  1.00 58.44  ? 288 LYS C N     1 
ATOM   10380 C  CA    . LYS C 1 288 ? -31.090 -0.652  -90.113  1.00 55.86  ? 288 LYS C CA    1 
ATOM   10381 C  C     . LYS C 1 288 ? -31.769 -0.860  -91.463  1.00 53.62  ? 288 LYS C C     1 
ATOM   10382 O  O     . LYS C 1 288 ? -31.457 -0.162  -92.422  1.00 53.65  ? 288 LYS C O     1 
ATOM   10383 C  CB    . LYS C 1 288 ? -29.989 -1.714  -89.981  1.00 56.76  ? 288 LYS C CB    1 
ATOM   10384 C  CG    . LYS C 1 288 ? -28.881 -1.614  -91.021  1.00 63.01  ? 288 LYS C CG    1 
ATOM   10385 C  CD    . LYS C 1 288 ? -27.660 -2.486  -90.757  1.00 68.31  ? 288 LYS C CD    1 
ATOM   10386 C  CE    . LYS C 1 288 ? -27.937 -3.967  -90.923  1.00 73.20  ? 288 LYS C CE    1 
ATOM   10387 N  NZ    . LYS C 1 288 ? -26.696 -4.780  -90.896  1.00 72.78  ? 288 LYS C NZ    1 
ATOM   10388 N  N     . SER C 1 289 ? -32.696 -1.824  -91.520  1.00 55.47  ? 289 SER C N     1 
ATOM   10389 C  CA    . SER C 1 289 ? -33.364 -2.189  -92.762  1.00 61.42  ? 289 SER C CA    1 
ATOM   10390 C  C     . SER C 1 289 ? -34.176 -1.026  -93.335  1.00 57.82  ? 289 SER C C     1 
ATOM   10391 O  O     . SER C 1 289 ? -34.522 -1.068  -94.506  1.00 63.51  ? 289 SER C O     1 
ATOM   10392 C  CB    . SER C 1 289 ? -34.237 -3.394  -92.574  1.00 54.52  ? 289 SER C CB    1 
ATOM   10393 O  OG    . SER C 1 289 ? -35.315 -3.063  -91.722  1.00 57.51  ? 289 SER C OG    1 
ATOM   10394 N  N     . GLN C 1 290 ? -34.442 0.020   -92.541  1.00 54.14  ? 290 GLN C N     1 
ATOM   10395 C  CA    . GLN C 1 290 ? -35.148 1.190   -93.041  1.00 55.27  ? 290 GLN C CA    1 
ATOM   10396 C  C     . GLN C 1 290 ? -34.243 2.091   -93.882  1.00 60.65  ? 290 GLN C C     1 
ATOM   10397 O  O     . GLN C 1 290 ? -34.751 2.964   -94.584  1.00 61.86  ? 290 GLN C O     1 
ATOM   10398 C  CB    . GLN C 1 290 ? -35.743 1.985   -91.879  1.00 60.18  ? 290 GLN C CB    1 
ATOM   10399 C  CG    . GLN C 1 290 ? -36.727 1.168   -91.054  1.00 60.32  ? 290 GLN C CG    1 
ATOM   10400 C  CD    . GLN C 1 290 ? -37.347 1.949   -89.919  1.00 69.82  ? 290 GLN C CD    1 
ATOM   10401 O  OE1   . GLN C 1 290 ? -36.804 2.014   -88.820  1.00 72.40  ? 290 GLN C OE1   1 
ATOM   10402 N  NE2   . GLN C 1 290 ? -38.523 2.510   -90.155  1.00 74.05  ? 290 GLN C NE2   1 
ATOM   10403 N  N     . TYR C 1 291 ? -32.914 1.902   -93.802  1.00 62.87  ? 291 TYR C N     1 
ATOM   10404 C  CA    . TYR C 1 291 ? -31.979 2.722   -94.562  1.00 54.91  ? 291 TYR C CA    1 
ATOM   10405 C  C     . TYR C 1 291 ? -30.975 1.908   -95.382  1.00 60.04  ? 291 TYR C C     1 
ATOM   10406 O  O     . TYR C 1 291 ? -30.266 2.481   -96.209  1.00 60.05  ? 291 TYR C O     1 
ATOM   10407 C  CB    . TYR C 1 291 ? -31.164 3.616   -93.631  1.00 54.14  ? 291 TYR C CB    1 
ATOM   10408 C  CG    . TYR C 1 291 ? -31.963 4.592   -92.813  1.00 51.69  ? 291 TYR C CG    1 
ATOM   10409 C  CD1   . TYR C 1 291 ? -32.367 5.821   -93.327  1.00 52.37  ? 291 TYR C CD1   1 
ATOM   10410 C  CD2   . TYR C 1 291 ? -32.334 4.271   -91.524  1.00 50.87  ? 291 TYR C CD2   1 
ATOM   10411 C  CE1   . TYR C 1 291 ? -33.097 6.718   -92.559  1.00 51.59  ? 291 TYR C CE1   1 
ATOM   10412 C  CE2   . TYR C 1 291 ? -33.084 5.144   -90.755  1.00 55.57  ? 291 TYR C CE2   1 
ATOM   10413 C  CZ    . TYR C 1 291 ? -33.456 6.371   -91.266  1.00 50.15  ? 291 TYR C CZ    1 
ATOM   10414 O  OH    . TYR C 1 291 ? -34.214 7.178   -90.466  1.00 57.03  ? 291 TYR C OH    1 
ATOM   10415 N  N     . TYR C 1 292 ? -30.881 0.588   -95.171  1.00 63.42  ? 292 TYR C N     1 
ATOM   10416 C  CA    . TYR C 1 292 ? -29.751 -0.145  -95.711  1.00 60.38  ? 292 TYR C CA    1 
ATOM   10417 C  C     . TYR C 1 292 ? -30.058 -1.635  -95.837  1.00 64.93  ? 292 TYR C C     1 
ATOM   10418 O  O     . TYR C 1 292 ? -30.467 -2.268  -94.863  1.00 65.05  ? 292 TYR C O     1 
ATOM   10419 C  CB    . TYR C 1 292 ? -28.531 0.067   -94.809  1.00 60.57  ? 292 TYR C CB    1 
ATOM   10420 C  CG    . TYR C 1 292 ? -27.278 -0.577  -95.331  1.00 54.85  ? 292 TYR C CG    1 
ATOM   10421 C  CD1   . TYR C 1 292 ? -26.740 -0.164  -96.536  1.00 61.63  ? 292 TYR C CD1   1 
ATOM   10422 C  CD2   . TYR C 1 292 ? -26.664 -1.631  -94.667  1.00 58.08  ? 292 TYR C CD2   1 
ATOM   10423 C  CE1   . TYR C 1 292 ? -25.608 -0.761  -97.063  1.00 63.49  ? 292 TYR C CE1   1 
ATOM   10424 C  CE2   . TYR C 1 292 ? -25.523 -2.236  -95.176  1.00 58.75  ? 292 TYR C CE2   1 
ATOM   10425 C  CZ    . TYR C 1 292 ? -24.988 -1.789  -96.375  1.00 61.54  ? 292 TYR C CZ    1 
ATOM   10426 O  OH    . TYR C 1 292 ? -23.863 -2.329  -96.945  1.00 59.97  ? 292 TYR C OH    1 
ATOM   10427 N  N     . ASP C 1 293 ? -29.778 -2.179  -97.033  1.00 64.56  ? 293 ASP C N     1 
ATOM   10428 C  CA    . ASP C 1 293 ? -30.044 -3.567  -97.378  1.00 70.46  ? 293 ASP C CA    1 
ATOM   10429 C  C     . ASP C 1 293 ? -28.952 -4.494  -96.851  1.00 67.92  ? 293 ASP C C     1 
ATOM   10430 O  O     . ASP C 1 293 ? -29.250 -5.607  -96.443  1.00 69.03  ? 293 ASP C O     1 
ATOM   10431 C  CB    . ASP C 1 293 ? -30.135 -3.773  -98.897  1.00 77.17  ? 293 ASP C CB    1 
ATOM   10432 C  CG    . ASP C 1 293 ? -31.539 -3.664  -99.468  1.00 89.44  ? 293 ASP C CG    1 
ATOM   10433 O  OD1   . ASP C 1 293 ? -32.436 -4.348  -98.935  1.00 98.01  ? 293 ASP C OD1   1 
ATOM   10434 O  OD2   . ASP C 1 293 ? -31.722 -2.922  -100.460 1.00 98.81  ? 293 ASP C OD2   1 
ATOM   10435 N  N     . GLY C 1 294 ? -27.689 -4.059  -96.919  1.00 68.77  ? 294 GLY C N     1 
ATOM   10436 C  CA    . GLY C 1 294 ? -26.557 -4.956  -96.747  1.00 66.30  ? 294 GLY C CA    1 
ATOM   10437 C  C     . GLY C 1 294 ? -26.515 -5.576  -95.355  1.00 67.65  ? 294 GLY C C     1 
ATOM   10438 O  O     . GLY C 1 294 ? -27.046 -5.012  -94.407  1.00 75.35  ? 294 GLY C O     1 
ATOM   10439 N  N     . ASP C 1 295 ? -25.832 -6.720  -95.247  1.00 75.48  ? 295 ASP C N     1 
ATOM   10440 C  CA    . ASP C 1 295 ? -25.784 -7.502  -94.023  1.00 86.94  ? 295 ASP C CA    1 
ATOM   10441 C  C     . ASP C 1 295 ? -24.754 -6.936  -93.045  1.00 90.09  ? 295 ASP C C     1 
ATOM   10442 O  O     . ASP C 1 295 ? -24.772 -7.288  -91.863  1.00 89.21  ? 295 ASP C O     1 
ATOM   10443 C  CB    . ASP C 1 295 ? -25.462 -8.965  -94.341  1.00 91.82  ? 295 ASP C CB    1 
ATOM   10444 C  CG    . ASP C 1 295 ? -26.491 -9.632  -95.235  1.00 97.10  ? 295 ASP C CG    1 
ATOM   10445 O  OD1   . ASP C 1 295 ? -27.618 -9.110  -95.324  1.00 109.04 ? 295 ASP C OD1   1 
ATOM   10446 O  OD2   . ASP C 1 295 ? -26.148 -10.650 -95.854  1.00 102.81 ? 295 ASP C OD2   1 
ATOM   10447 N  N     . GLY C 1 296 ? -23.844 -6.090  -93.550  1.00 84.04  ? 296 GLY C N     1 
ATOM   10448 C  CA    . GLY C 1 296 ? -22.771 -5.534  -92.741  1.00 83.35  ? 296 GLY C CA    1 
ATOM   10449 C  C     . GLY C 1 296 ? -23.170 -4.236  -92.034  1.00 78.25  ? 296 GLY C C     1 
ATOM   10450 O  O     . GLY C 1 296 ? -24.351 -3.898  -91.931  1.00 65.20  ? 296 GLY C O     1 
ATOM   10451 N  N     . PRO C 1 297 ? -22.190 -3.475  -91.500  1.00 71.05  ? 297 PRO C N     1 
ATOM   10452 C  CA    . PRO C 1 297 ? -22.469 -2.176  -90.896  1.00 70.05  ? 297 PRO C CA    1 
ATOM   10453 C  C     . PRO C 1 297 ? -22.671 -1.120  -91.973  1.00 67.11  ? 297 PRO C C     1 
ATOM   10454 O  O     . PRO C 1 297 ? -22.198 -1.256  -93.096  1.00 64.42  ? 297 PRO C O     1 
ATOM   10455 C  CB    . PRO C 1 297 ? -21.205 -1.910  -90.066  1.00 72.68  ? 297 PRO C CB    1 
ATOM   10456 C  CG    . PRO C 1 297 ? -20.110 -2.569  -90.875  1.00 73.08  ? 297 PRO C CG    1 
ATOM   10457 C  CD    . PRO C 1 297 ? -20.761 -3.821  -91.433  1.00 74.18  ? 297 PRO C CD    1 
ATOM   10458 N  N     . ILE C 1 298 ? -23.344 -0.037  -91.597  1.00 68.20  ? 298 ILE C N     1 
ATOM   10459 C  CA    . ILE C 1 298 ? -23.779 0.951   -92.566  1.00 67.42  ? 298 ILE C CA    1 
ATOM   10460 C  C     . ILE C 1 298 ? -22.561 1.657   -93.163  1.00 67.55  ? 298 ILE C C     1 
ATOM   10461 O  O     . ILE C 1 298 ? -21.553 1.832   -92.485  1.00 67.72  ? 298 ILE C O     1 
ATOM   10462 C  CB    . ILE C 1 298 ? -24.778 1.927   -91.917  1.00 68.67  ? 298 ILE C CB    1 
ATOM   10463 C  CG1   . ILE C 1 298 ? -24.124 2.800   -90.839  1.00 69.35  ? 298 ILE C CG1   1 
ATOM   10464 C  CG2   . ILE C 1 298 ? -25.984 1.158   -91.380  1.00 67.04  ? 298 ILE C CG2   1 
ATOM   10465 C  CD1   . ILE C 1 298 ? -24.799 4.139   -90.650  1.00 70.50  ? 298 ILE C CD1   1 
ATOM   10466 N  N     . PRO C 1 299 ? -22.596 2.030   -94.464  1.00 61.42  ? 299 PRO C N     1 
ATOM   10467 C  CA    . PRO C 1 299 ? -21.555 2.852   -95.074  1.00 61.08  ? 299 PRO C CA    1 
ATOM   10468 C  C     . PRO C 1 299 ? -21.832 4.347   -94.935  1.00 56.99  ? 299 PRO C C     1 
ATOM   10469 O  O     . PRO C 1 299 ? -22.915 4.744   -94.523  1.00 51.96  ? 299 PRO C O     1 
ATOM   10470 C  CB    . PRO C 1 299 ? -21.606 2.418   -96.549  1.00 65.75  ? 299 PRO C CB    1 
ATOM   10471 C  CG    . PRO C 1 299 ? -23.067 2.063   -96.789  1.00 66.61  ? 299 PRO C CG    1 
ATOM   10472 C  CD    . PRO C 1 299 ? -23.609 1.613   -95.444  1.00 65.86  ? 299 PRO C CD    1 
ATOM   10473 N  N     . PRO C 1 300 ? -20.850 5.212   -95.263  1.00 62.33  ? 300 PRO C N     1 
ATOM   10474 C  CA    . PRO C 1 300 ? -20.979 6.659   -95.088  1.00 64.12  ? 300 PRO C CA    1 
ATOM   10475 C  C     . PRO C 1 300 ? -22.207 7.327   -95.700  1.00 66.92  ? 300 PRO C C     1 
ATOM   10476 O  O     . PRO C 1 300 ? -22.719 8.279   -95.117  1.00 70.82  ? 300 PRO C O     1 
ATOM   10477 C  CB    . PRO C 1 300 ? -19.729 7.230   -95.785  1.00 64.75  ? 300 PRO C CB    1 
ATOM   10478 C  CG    . PRO C 1 300 ? -18.711 6.122   -95.673  1.00 68.78  ? 300 PRO C CG    1 
ATOM   10479 C  CD    . PRO C 1 300 ? -19.514 4.834   -95.751  1.00 65.99  ? 300 PRO C CD    1 
ATOM   10480 N  N     . SER C 1 301 ? -22.644 6.862   -96.881  1.00 66.27  ? 301 SER C N     1 
ATOM   10481 C  CA    . SER C 1 301 ? -23.758 7.491   -97.586  1.00 62.83  ? 301 SER C CA    1 
ATOM   10482 C  C     . SER C 1 301 ? -25.061 7.306   -96.798  1.00 56.92  ? 301 SER C C     1 
ATOM   10483 O  O     . SER C 1 301 ? -25.859 8.235   -96.672  1.00 50.63  ? 301 SER C O     1 
ATOM   10484 C  CB    . SER C 1 301 ? -23.861 7.008   -99.026  1.00 59.24  ? 301 SER C CB    1 
ATOM   10485 O  OG    . SER C 1 301 ? -23.946 5.591   -99.097  1.00 63.32  ? 301 SER C OG    1 
ATOM   10486 N  N     . VAL C 1 302 ? -25.236 6.114   -96.220  1.00 50.56  ? 302 VAL C N     1 
ATOM   10487 C  CA    . VAL C 1 302 ? -26.378 5.823   -95.379  1.00 54.63  ? 302 VAL C CA    1 
ATOM   10488 C  C     . VAL C 1 302 ? -26.320 6.676   -94.111  1.00 61.57  ? 302 VAL C C     1 
ATOM   10489 O  O     . VAL C 1 302 ? -27.354 7.130   -93.620  1.00 54.19  ? 302 VAL C O     1 
ATOM   10490 C  CB    . VAL C 1 302 ? -26.438 4.317   -95.053  1.00 58.36  ? 302 VAL C CB    1 
ATOM   10491 C  CG1   . VAL C 1 302 ? -27.388 4.012   -93.906  1.00 62.38  ? 302 VAL C CG1   1 
ATOM   10492 C  CG2   . VAL C 1 302 ? -26.814 3.499   -96.273  1.00 53.37  ? 302 VAL C CG2   1 
ATOM   10493 N  N     . ALA C 1 303 ? -25.113 6.875   -93.564  1.00 60.37  ? 303 ALA C N     1 
ATOM   10494 C  CA    . ALA C 1 303 ? -24.953 7.715   -92.384  1.00 61.14  ? 303 ALA C CA    1 
ATOM   10495 C  C     . ALA C 1 303 ? -25.506 9.105   -92.673  1.00 54.13  ? 303 ALA C C     1 
ATOM   10496 O  O     . ALA C 1 303 ? -26.265 9.629   -91.867  1.00 55.47  ? 303 ALA C O     1 
ATOM   10497 C  CB    . ALA C 1 303 ? -23.504 7.787   -91.929  1.00 59.05  ? 303 ALA C CB    1 
ATOM   10498 N  N     . LYS C 1 304 ? -25.127 9.701   -93.809  1.00 55.28  ? 304 LYS C N     1 
ATOM   10499 C  CA    . LYS C 1 304 ? -25.589 11.046  -94.121  1.00 64.31  ? 304 LYS C CA    1 
ATOM   10500 C  C     . LYS C 1 304 ? -27.110 11.067  -94.286  1.00 58.66  ? 304 LYS C C     1 
ATOM   10501 O  O     . LYS C 1 304 ? -27.753 12.019  -93.854  1.00 52.00  ? 304 LYS C O     1 
ATOM   10502 C  CB    . LYS C 1 304 ? -24.900 11.602  -95.369  1.00 71.69  ? 304 LYS C CB    1 
ATOM   10503 C  CG    . LYS C 1 304 ? -23.468 12.092  -95.166  1.00 88.98  ? 304 LYS C CG    1 
ATOM   10504 C  CD    . LYS C 1 304 ? -22.363 11.116  -95.567  1.00 104.59 ? 304 LYS C CD    1 
ATOM   10505 C  CE    . LYS C 1 304 ? -22.391 10.681  -97.023  1.00 114.90 ? 304 LYS C CE    1 
ATOM   10506 N  NZ    . LYS C 1 304 ? -21.969 11.752  -97.960  1.00 117.49 ? 304 LYS C NZ    1 
ATOM   10507 N  N     . THR C 1 305 ? -27.682 10.038  -94.932  1.00 63.15  ? 305 THR C N     1 
ATOM   10508 C  CA    . THR C 1 305 ? -29.127 9.972   -95.127  1.00 64.17  ? 305 THR C CA    1 
ATOM   10509 C  C     . THR C 1 305 ? -29.786 9.993   -93.745  1.00 61.30  ? 305 THR C C     1 
ATOM   10510 O  O     . THR C 1 305 ? -30.618 10.854  -93.442  1.00 54.79  ? 305 THR C O     1 
ATOM   10511 C  CB    . THR C 1 305 ? -29.553 8.739   -95.951  1.00 64.19  ? 305 THR C CB    1 
ATOM   10512 O  OG1   . THR C 1 305 ? -28.964 8.777   -97.248  1.00 57.34  ? 305 THR C OG1   1 
ATOM   10513 C  CG2   . THR C 1 305 ? -31.050 8.631   -96.151  1.00 57.48  ? 305 THR C CG2   1 
ATOM   10514 N  N     . MET C 1 306 ? -29.330 9.061   -92.896  1.00 55.61  ? 306 MET C N     1 
ATOM   10515 C  CA    . MET C 1 306 ? -29.843 8.894   -91.548  1.00 53.81  ? 306 MET C CA    1 
ATOM   10516 C  C     . MET C 1 306 ? -29.847 10.219  -90.801  1.00 52.05  ? 306 MET C C     1 
ATOM   10517 O  O     . MET C 1 306 ? -30.794 10.509  -90.082  1.00 50.97  ? 306 MET C O     1 
ATOM   10518 C  CB    . MET C 1 306 ? -28.988 7.888   -90.776  1.00 55.66  ? 306 MET C CB    1 
ATOM   10519 C  CG    . MET C 1 306 ? -29.541 6.510   -90.836  1.00 52.42  ? 306 MET C CG    1 
ATOM   10520 S  SD    . MET C 1 306 ? -28.282 5.315   -90.442  1.00 58.12  ? 306 MET C SD    1 
ATOM   10521 C  CE    . MET C 1 306 ? -28.433 5.284   -88.656  1.00 63.87  ? 306 MET C CE    1 
ATOM   10522 N  N     . MET C 1 307 ? -28.764 10.987  -90.956  1.00 50.05  ? 307 MET C N     1 
ATOM   10523 C  CA    . MET C 1 307 ? -28.586 12.248  -90.244  1.00 58.34  ? 307 MET C CA    1 
ATOM   10524 C  C     . MET C 1 307 ? -29.637 13.262  -90.685  1.00 55.93  ? 307 MET C C     1 
ATOM   10525 O  O     . MET C 1 307 ? -30.247 13.916  -89.852  1.00 57.32  ? 307 MET C O     1 
ATOM   10526 C  CB    . MET C 1 307 ? -27.205 12.848  -90.530  1.00 55.70  ? 307 MET C CB    1 
ATOM   10527 C  CG    . MET C 1 307 ? -26.120 12.328  -89.613  1.00 57.90  ? 307 MET C CG    1 
ATOM   10528 S  SD    . MET C 1 307 ? -24.508 12.871  -90.209  1.00 61.79  ? 307 MET C SD    1 
ATOM   10529 C  CE    . MET C 1 307 ? -24.598 14.599  -89.736  1.00 58.10  ? 307 MET C CE    1 
ATOM   10530 N  N     . ALA C 1 308 ? -29.777 13.427  -92.006  1.00 59.29  ? 308 ALA C N     1 
ATOM   10531 C  CA    . ALA C 1 308 ? -30.769 14.331  -92.564  1.00 62.13  ? 308 ALA C CA    1 
ATOM   10532 C  C     . ALA C 1 308 ? -32.175 13.888  -92.159  1.00 57.79  ? 308 ALA C C     1 
ATOM   10533 O  O     . ALA C 1 308 ? -33.003 14.698  -91.763  1.00 53.41  ? 308 ALA C O     1 
ATOM   10534 C  CB    . ALA C 1 308 ? -30.619 14.382  -94.062  1.00 60.87  ? 308 ALA C CB    1 
ATOM   10535 N  N     . ASP C 1 309 ? -32.440 12.586  -92.251  1.00 58.90  ? 309 ASP C N     1 
ATOM   10536 C  CA    . ASP C 1 309 ? -33.765 12.064  -91.975  1.00 54.21  ? 309 ASP C CA    1 
ATOM   10537 C  C     . ASP C 1 309 ? -34.186 12.350  -90.531  1.00 59.04  ? 309 ASP C C     1 
ATOM   10538 O  O     . ASP C 1 309 ? -35.313 12.795  -90.293  1.00 57.22  ? 309 ASP C O     1 
ATOM   10539 C  CB    . ASP C 1 309 ? -33.795 10.569  -92.281  1.00 65.64  ? 309 ASP C CB    1 
ATOM   10540 C  CG    . ASP C 1 309 ? -35.202 10.008  -92.261  1.00 69.40  ? 309 ASP C CG    1 
ATOM   10541 O  OD1   . ASP C 1 309 ? -36.081 10.675  -92.859  1.00 62.98  ? 309 ASP C OD1   1 
ATOM   10542 O  OD2   . ASP C 1 309 ? -35.400 8.923   -91.641  1.00 61.82  ? 309 ASP C OD2   1 
ATOM   10543 N  N     . LEU C 1 310 ? -33.269 12.117  -89.574  1.00 50.66  ? 310 LEU C N     1 
ATOM   10544 C  CA    . LEU C 1 310 ? -33.599 12.100  -88.155  1.00 51.46  ? 310 LEU C CA    1 
ATOM   10545 C  C     . LEU C 1 310 ? -33.239 13.409  -87.448  1.00 49.85  ? 310 LEU C C     1 
ATOM   10546 O  O     . LEU C 1 310 ? -33.500 13.536  -86.261  1.00 49.32  ? 310 LEU C O     1 
ATOM   10547 C  CB    . LEU C 1 310 ? -32.849 10.938  -87.502  1.00 47.43  ? 310 LEU C CB    1 
ATOM   10548 C  CG    . LEU C 1 310 ? -33.261 9.536   -87.946  1.00 54.90  ? 310 LEU C CG    1 
ATOM   10549 C  CD1   . LEU C 1 310 ? -32.215 8.502   -87.549  1.00 55.22  ? 310 LEU C CD1   1 
ATOM   10550 C  CD2   . LEU C 1 310 ? -34.606 9.148   -87.358  1.00 55.56  ? 310 LEU C CD2   1 
ATOM   10551 N  N     . ASP C 1 311 ? -32.635 14.377  -88.139  1.00 54.44  ? 311 ASP C N     1 
ATOM   10552 C  CA    . ASP C 1 311 ? -32.101 15.571  -87.476  1.00 63.01  ? 311 ASP C CA    1 
ATOM   10553 C  C     . ASP C 1 311 ? -31.143 15.207  -86.337  1.00 57.63  ? 311 ASP C C     1 
ATOM   10554 O  O     . ASP C 1 311 ? -31.257 15.710  -85.217  1.00 55.49  ? 311 ASP C O     1 
ATOM   10555 C  CB    . ASP C 1 311 ? -33.208 16.473  -86.937  1.00 63.11  ? 311 ASP C CB    1 
ATOM   10556 C  CG    . ASP C 1 311 ? -34.055 17.067  -88.040  1.00 68.37  ? 311 ASP C CG    1 
ATOM   10557 O  OD1   . ASP C 1 311 ? -33.816 16.715  -89.207  1.00 68.71  ? 311 ASP C OD1   1 
ATOM   10558 O  OD2   . ASP C 1 311 ? -34.920 17.890  -87.719  1.00 73.15  ? 311 ASP C OD2   1 
ATOM   10559 N  N     . LEU C 1 312 ? -30.208 14.313  -86.654  1.00 59.50  ? 312 LEU C N     1 
ATOM   10560 C  CA    . LEU C 1 312 ? -29.163 13.894  -85.744  1.00 55.71  ? 312 LEU C CA    1 
ATOM   10561 C  C     . LEU C 1 312 ? -27.816 14.174  -86.400  1.00 59.11  ? 312 LEU C C     1 
ATOM   10562 O  O     . LEU C 1 312 ? -27.729 14.370  -87.612  1.00 57.64  ? 312 LEU C O     1 
ATOM   10563 C  CB    . LEU C 1 312 ? -29.321 12.407  -85.437  1.00 55.04  ? 312 LEU C CB    1 
ATOM   10564 C  CG    . LEU C 1 312 ? -30.566 12.021  -84.640  1.00 53.68  ? 312 LEU C CG    1 
ATOM   10565 C  CD1   . LEU C 1 312 ? -30.635 10.515  -84.483  1.00 51.47  ? 312 LEU C CD1   1 
ATOM   10566 C  CD2   . LEU C 1 312 ? -30.582 12.689  -83.269  1.00 56.32  ? 312 LEU C CD2   1 
ATOM   10567 N  N     . GLY C 1 313 ? -26.786 14.248  -85.549  1.00 56.57  ? 313 GLY C N     1 
ATOM   10568 C  CA    . GLY C 1 313 ? -25.405 14.336  -85.975  1.00 49.46  ? 313 GLY C CA    1 
ATOM   10569 C  C     . GLY C 1 313 ? -24.710 12.985  -85.881  1.00 48.43  ? 313 GLY C C     1 
ATOM   10570 O  O     . GLY C 1 313 ? -25.288 11.974  -85.475  1.00 47.93  ? 313 GLY C O     1 
ATOM   10571 N  N     . MET C 1 314 ? -23.437 12.990  -86.274  1.00 50.16  ? 314 MET C N     1 
ATOM   10572 C  CA    . MET C 1 314 ? -22.573 11.861  -86.004  1.00 48.51  ? 314 MET C CA    1 
ATOM   10573 C  C     . MET C 1 314 ? -22.414 11.733  -84.493  1.00 45.46  ? 314 MET C C     1 
ATOM   10574 O  O     . MET C 1 314 ? -22.251 10.630  -83.979  1.00 46.07  ? 314 MET C O     1 
ATOM   10575 C  CB    . MET C 1 314 ? -21.218 12.060  -86.692  1.00 51.48  ? 314 MET C CB    1 
ATOM   10576 C  CG    . MET C 1 314 ? -21.320 12.025  -88.206  1.00 52.71  ? 314 MET C CG    1 
ATOM   10577 S  SD    . MET C 1 314 ? -22.231 10.581  -88.839  1.00 62.87  ? 314 MET C SD    1 
ATOM   10578 C  CE    . MET C 1 314 ? -21.351 9.179   -88.165  1.00 51.56  ? 314 MET C CE    1 
ATOM   10579 N  N     . TRP C 1 315 ? -22.495 12.879  -83.796  1.00 41.04  ? 315 TRP C N     1 
ATOM   10580 C  CA    . TRP C 1 315 ? -22.431 12.914  -82.346  1.00 42.93  ? 315 TRP C CA    1 
ATOM   10581 C  C     . TRP C 1 315 ? -23.563 13.774  -81.814  1.00 42.83  ? 315 TRP C C     1 
ATOM   10582 O  O     . TRP C 1 315 ? -23.834 14.834  -82.365  1.00 44.91  ? 315 TRP C O     1 
ATOM   10583 C  CB    . TRP C 1 315 ? -21.072 13.451  -81.878  1.00 43.76  ? 315 TRP C CB    1 
ATOM   10584 C  CG    . TRP C 1 315 ? -19.951 12.521  -82.207  1.00 40.95  ? 315 TRP C CG    1 
ATOM   10585 C  CD1   . TRP C 1 315 ? -18.982 12.724  -83.138  1.00 44.80  ? 315 TRP C CD1   1 
ATOM   10586 C  CD2   . TRP C 1 315 ? -19.667 11.246  -81.603  1.00 45.38  ? 315 TRP C CD2   1 
ATOM   10587 N  NE1   . TRP C 1 315 ? -18.126 11.659  -83.159  1.00 42.71  ? 315 TRP C NE1   1 
ATOM   10588 C  CE2   . TRP C 1 315 ? -18.517 10.736  -82.238  1.00 42.80  ? 315 TRP C CE2   1 
ATOM   10589 C  CE3   . TRP C 1 315 ? -20.268 10.477  -80.604  1.00 49.89  ? 315 TRP C CE3   1 
ATOM   10590 C  CZ2   . TRP C 1 315 ? -17.956 9.503   -81.912  1.00 49.22  ? 315 TRP C CZ2   1 
ATOM   10591 C  CZ3   . TRP C 1 315 ? -19.710 9.261   -80.275  1.00 54.46  ? 315 TRP C CZ3   1 
ATOM   10592 C  CH2   . TRP C 1 315 ? -18.565 8.782   -80.915  1.00 51.02  ? 315 TRP C CH2   1 
ATOM   10593 N  N     . ASN C 1 316 ? -24.176 13.312  -80.722  1.00 44.34  ? 316 ASN C N     1 
ATOM   10594 C  CA    . ASN C 1 316 ? -25.394 13.923  -80.214  1.00 46.61  ? 316 ASN C CA    1 
ATOM   10595 C  C     . ASN C 1 316 ? -25.256 14.118  -78.713  1.00 47.82  ? 316 ASN C C     1 
ATOM   10596 O  O     . ASN C 1 316 ? -25.264 13.143  -77.948  1.00 42.24  ? 316 ASN C O     1 
ATOM   10597 C  CB    . ASN C 1 316 ? -26.613 13.087  -80.609  1.00 47.77  ? 316 ASN C CB    1 
ATOM   10598 C  CG    . ASN C 1 316 ? -26.712 12.958  -82.116  1.00 49.34  ? 316 ASN C CG    1 
ATOM   10599 O  OD1   . ASN C 1 316 ? -26.865 13.957  -82.818  1.00 47.74  ? 316 ASN C OD1   1 
ATOM   10600 N  ND2   . ASN C 1 316 ? -26.568 11.747  -82.632  1.00 56.21  ? 316 ASN C ND2   1 
ATOM   10601 N  N     . PHE C 1 317 ? -25.081 15.399  -78.344  1.00 45.00  ? 317 PHE C N     1 
ATOM   10602 C  CA    . PHE C 1 317 ? -24.856 15.786  -76.968  1.00 49.40  ? 317 PHE C CA    1 
ATOM   10603 C  C     . PHE C 1 317 ? -26.187 16.179  -76.320  1.00 50.86  ? 317 PHE C C     1 
ATOM   10604 O  O     . PHE C 1 317 ? -26.716 17.259  -76.587  1.00 48.88  ? 317 PHE C O     1 
ATOM   10605 C  CB    . PHE C 1 317 ? -23.815 16.903  -76.914  1.00 43.57  ? 317 PHE C CB    1 
ATOM   10606 C  CG    . PHE C 1 317 ? -23.740 17.574  -75.571  1.00 41.32  ? 317 PHE C CG    1 
ATOM   10607 C  CD1   . PHE C 1 317 ? -23.806 16.831  -74.407  1.00 38.49  ? 317 PHE C CD1   1 
ATOM   10608 C  CD2   . PHE C 1 317 ? -23.539 18.942  -75.479  1.00 37.84  ? 317 PHE C CD2   1 
ATOM   10609 C  CE1   . PHE C 1 317 ? -23.725 17.457  -73.174  1.00 44.12  ? 317 PHE C CE1   1 
ATOM   10610 C  CE2   . PHE C 1 317 ? -23.436 19.560  -74.249  1.00 37.47  ? 317 PHE C CE2   1 
ATOM   10611 C  CZ    . PHE C 1 317 ? -23.510 18.815  -73.099  1.00 40.98  ? 317 PHE C CZ    1 
ATOM   10612 N  N     . CYS C 1 318 ? -26.711 15.273  -75.486  1.00 52.10  ? 318 CYS C N     1 
ATOM   10613 C  CA    . CYS C 1 318 ? -27.930 15.492  -74.717  1.00 56.20  ? 318 CYS C CA    1 
ATOM   10614 C  C     . CYS C 1 318 ? -27.571 15.805  -73.272  1.00 53.25  ? 318 CYS C C     1 
ATOM   10615 O  O     . CYS C 1 318 ? -26.963 14.970  -72.600  1.00 47.36  ? 318 CYS C O     1 
ATOM   10616 C  CB    . CYS C 1 318 ? -28.868 14.287  -74.730  1.00 60.98  ? 318 CYS C CB    1 
ATOM   10617 S  SG    . CYS C 1 318 ? -29.725 14.083  -76.312  1.00 80.54  ? 318 CYS C SG    1 
ATOM   10618 N  N     . GLY C 1 319 ? -27.929 17.028  -72.850  1.00 48.03  ? 319 GLY C N     1 
ATOM   10619 C  CA    . GLY C 1 319 ? -27.879 17.442  -71.460  1.00 52.98  ? 319 GLY C CA    1 
ATOM   10620 C  C     . GLY C 1 319 ? -29.171 18.125  -71.008  1.00 52.31  ? 319 GLY C C     1 
ATOM   10621 O  O     . GLY C 1 319 ? -30.166 18.188  -71.730  1.00 47.49  ? 319 GLY C O     1 
ATOM   10622 N  N     . ALA C 1 320 ? -29.155 18.622  -69.775  1.00 48.98  ? 320 ALA C N     1 
ATOM   10623 C  CA    . ALA C 1 320 ? -30.312 19.316  -69.252  1.00 45.25  ? 320 ALA C CA    1 
ATOM   10624 C  C     . ALA C 1 320 ? -29.890 20.383  -68.250  1.00 47.09  ? 320 ALA C C     1 
ATOM   10625 O  O     . ALA C 1 320 ? -28.947 20.183  -67.487  1.00 44.86  ? 320 ALA C O     1 
ATOM   10626 C  CB    . ALA C 1 320 ? -31.241 18.322  -68.627  1.00 45.55  ? 320 ALA C CB    1 
ATOM   10627 N  N     . LEU C 1 321 ? -30.680 21.467  -68.214  1.00 42.29  ? 321 LEU C N     1 
ATOM   10628 C  CA    . LEU C 1 321 ? -30.498 22.555  -67.276  1.00 43.29  ? 321 LEU C CA    1 
ATOM   10629 C  C     . LEU C 1 321 ? -31.501 22.401  -66.145  1.00 44.61  ? 321 LEU C C     1 
ATOM   10630 O  O     . LEU C 1 321 ? -32.661 22.067  -66.386  1.00 47.25  ? 321 LEU C O     1 
ATOM   10631 C  CB    . LEU C 1 321 ? -30.723 23.880  -68.000  1.00 46.74  ? 321 LEU C CB    1 
ATOM   10632 C  CG    . LEU C 1 321 ? -30.047 24.023  -69.359  1.00 49.07  ? 321 LEU C CG    1 
ATOM   10633 C  CD1   . LEU C 1 321 ? -30.592 25.237  -70.096  1.00 51.61  ? 321 LEU C CD1   1 
ATOM   10634 C  CD2   . LEU C 1 321 ? -28.540 24.129  -69.211  1.00 55.18  ? 321 LEU C CD2   1 
ATOM   10635 N  N     . TYR C 1 322 ? -31.045 22.648  -64.912  1.00 45.01  ? 322 TYR C N     1 
ATOM   10636 C  CA    . TYR C 1 322 ? -31.908 22.525  -63.752  1.00 45.66  ? 322 TYR C CA    1 
ATOM   10637 C  C     . TYR C 1 322 ? -31.830 23.794  -62.904  1.00 52.15  ? 322 TYR C C     1 
ATOM   10638 O  O     . TYR C 1 322 ? -30.753 24.359  -62.722  1.00 50.29  ? 322 TYR C O     1 
ATOM   10639 C  CB    . TYR C 1 322 ? -31.541 21.312  -62.907  1.00 40.47  ? 322 TYR C CB    1 
ATOM   10640 C  CG    . TYR C 1 322 ? -31.378 20.003  -63.641  1.00 43.56  ? 322 TYR C CG    1 
ATOM   10641 C  CD1   . TYR C 1 322 ? -30.250 19.750  -64.408  1.00 39.24  ? 322 TYR C CD1   1 
ATOM   10642 C  CD2   . TYR C 1 322 ? -32.293 18.974  -63.497  1.00 41.64  ? 322 TYR C CD2   1 
ATOM   10643 C  CE1   . TYR C 1 322 ? -30.060 18.538  -65.048  1.00 36.19  ? 322 TYR C CE1   1 
ATOM   10644 C  CE2   . TYR C 1 322 ? -32.136 17.761  -64.163  1.00 43.82  ? 322 TYR C CE2   1 
ATOM   10645 C  CZ    . TYR C 1 322 ? -31.006 17.537  -64.938  1.00 41.68  ? 322 TYR C CZ    1 
ATOM   10646 O  OH    . TYR C 1 322 ? -30.789 16.332  -65.576  1.00 43.89  ? 322 TYR C OH    1 
ATOM   10647 N  N     . GLY C 1 323 ? -32.991 24.223  -62.384  1.00 46.38  ? 323 GLY C N     1 
ATOM   10648 C  CA    . GLY C 1 323 ? -33.040 25.339  -61.459  1.00 50.40  ? 323 GLY C CA    1 
ATOM   10649 C  C     . GLY C 1 323 ? -33.931 26.474  -61.956  1.00 47.30  ? 323 GLY C C     1 
ATOM   10650 O  O     . GLY C 1 323 ? -34.608 26.351  -62.962  1.00 50.94  ? 323 GLY C O     1 
ATOM   10651 N  N     . PRO C 1 324 ? -33.972 27.620  -61.256  1.00 48.94  ? 324 PRO C N     1 
ATOM   10652 C  CA    . PRO C 1 324 ? -34.793 28.731  -61.722  1.00 52.74  ? 324 PRO C CA    1 
ATOM   10653 C  C     . PRO C 1 324 ? -34.293 29.244  -63.069  1.00 55.45  ? 324 PRO C C     1 
ATOM   10654 O  O     . PRO C 1 324 ? -33.115 29.088  -63.397  1.00 51.47  ? 324 PRO C O     1 
ATOM   10655 C  CB    . PRO C 1 324 ? -34.675 29.759  -60.590  1.00 51.96  ? 324 PRO C CB    1 
ATOM   10656 C  CG    . PRO C 1 324 ? -33.380 29.393  -59.870  1.00 49.84  ? 324 PRO C CG    1 
ATOM   10657 C  CD    . PRO C 1 324 ? -33.270 27.891  -59.987  1.00 45.54  ? 324 PRO C CD    1 
ATOM   10658 N  N     . PRO C 1 325 ? -35.176 29.850  -63.900  1.00 61.14  ? 325 PRO C N     1 
ATOM   10659 C  CA    . PRO C 1 325 ? -34.784 30.359  -65.219  1.00 60.12  ? 325 PRO C CA    1 
ATOM   10660 C  C     . PRO C 1 325 ? -33.525 31.228  -65.254  1.00 54.56  ? 325 PRO C C     1 
ATOM   10661 O  O     . PRO C 1 325 ? -32.717 31.072  -66.169  1.00 54.75  ? 325 PRO C O     1 
ATOM   10662 C  CB    . PRO C 1 325 ? -36.026 31.154  -65.658  1.00 62.33  ? 325 PRO C CB    1 
ATOM   10663 C  CG    . PRO C 1 325 ? -37.168 30.403  -65.011  1.00 62.81  ? 325 PRO C CG    1 
ATOM   10664 C  CD    . PRO C 1 325 ? -36.619 30.013  -63.653  1.00 60.42  ? 325 PRO C CD    1 
ATOM   10665 N  N     . PRO C 1 326 ? -33.297 32.150  -64.284  1.00 55.48  ? 326 PRO C N     1 
ATOM   10666 C  CA    . PRO C 1 326 ? -32.092 32.980  -64.303  1.00 51.78  ? 326 PRO C CA    1 
ATOM   10667 C  C     . PRO C 1 326 ? -30.827 32.125  -64.272  1.00 52.82  ? 326 PRO C C     1 
ATOM   10668 O  O     . PRO C 1 326 ? -29.840 32.462  -64.920  1.00 55.04  ? 326 PRO C O     1 
ATOM   10669 C  CB    . PRO C 1 326 ? -32.251 33.877  -63.061  1.00 55.11  ? 326 PRO C CB    1 
ATOM   10670 C  CG    . PRO C 1 326 ? -33.745 33.863  -62.782  1.00 50.25  ? 326 PRO C CG    1 
ATOM   10671 C  CD    . PRO C 1 326 ? -34.152 32.444  -63.112  1.00 50.72  ? 326 PRO C CD    1 
ATOM   10672 N  N     . VAL C 1 327 ? -30.899 30.976  -63.588  1.00 54.79  ? 327 VAL C N     1 
ATOM   10673 C  CA    . VAL C 1 327 ? -29.781 30.047  -63.490  1.00 55.16  ? 327 VAL C CA    1 
ATOM   10674 C  C     . VAL C 1 327 ? -29.600 29.286  -64.806  1.00 51.03  ? 327 VAL C C     1 
ATOM   10675 O  O     . VAL C 1 327 ? -28.487 29.189  -65.332  1.00 47.54  ? 327 VAL C O     1 
ATOM   10676 C  CB    . VAL C 1 327 ? -29.983 29.061  -62.319  1.00 51.79  ? 327 VAL C CB    1 
ATOM   10677 C  CG1   . VAL C 1 327 ? -28.948 27.947  -62.339  1.00 49.20  ? 327 VAL C CG1   1 
ATOM   10678 C  CG2   . VAL C 1 327 ? -29.982 29.776  -60.982  1.00 54.56  ? 327 VAL C CG2   1 
ATOM   10679 N  N     . MET C 1 328 ? -30.698 28.697  -65.296  1.00 47.53  ? 328 MET C N     1 
ATOM   10680 C  CA    . MET C 1 328 ? -30.682 27.917  -66.522  1.00 48.72  ? 328 MET C CA    1 
ATOM   10681 C  C     . MET C 1 328 ? -30.171 28.788  -67.667  1.00 51.16  ? 328 MET C C     1 
ATOM   10682 O  O     . MET C 1 328 ? -29.359 28.332  -68.476  1.00 49.00  ? 328 MET C O     1 
ATOM   10683 C  CB    . MET C 1 328 ? -32.075 27.360  -66.827  1.00 50.34  ? 328 MET C CB    1 
ATOM   10684 C  CG    . MET C 1 328 ? -32.481 26.257  -65.837  1.00 55.46  ? 328 MET C CG    1 
ATOM   10685 S  SD    . MET C 1 328 ? -33.943 25.239  -66.266  1.00 56.26  ? 328 MET C SD    1 
ATOM   10686 C  CE    . MET C 1 328 ? -35.210 26.493  -66.464  1.00 52.08  ? 328 MET C CE    1 
ATOM   10687 N  N     . ASP C 1 329 ? -30.622 30.052  -67.692  1.00 52.38  ? 329 ASP C N     1 
ATOM   10688 C  CA    . ASP C 1 329 ? -30.254 30.976  -68.752  1.00 57.58  ? 329 ASP C CA    1 
ATOM   10689 C  C     . ASP C 1 329 ? -28.748 31.240  -68.711  1.00 53.01  ? 329 ASP C C     1 
ATOM   10690 O  O     . ASP C 1 329 ? -28.118 31.284  -69.762  1.00 50.74  ? 329 ASP C O     1 
ATOM   10691 C  CB    . ASP C 1 329 ? -31.037 32.296  -68.675  1.00 58.49  ? 329 ASP C CB    1 
ATOM   10692 C  CG    . ASP C 1 329 ? -32.491 32.219  -69.118  1.00 60.59  ? 329 ASP C CG    1 
ATOM   10693 O  OD1   . ASP C 1 329 ? -32.984 31.104  -69.391  1.00 66.18  ? 329 ASP C OD1   1 
ATOM   10694 O  OD2   . ASP C 1 329 ? -33.120 33.276  -69.171  1.00 62.89  ? 329 ASP C OD2   1 
ATOM   10695 N  N     . THR C 1 330 ? -28.184 31.436  -67.511  1.00 51.21  ? 330 THR C N     1 
ATOM   10696 C  CA    . THR C 1 330 ? -26.773 31.785  -67.385  1.00 52.64  ? 330 THR C CA    1 
ATOM   10697 C  C     . THR C 1 330 ? -25.913 30.599  -67.800  1.00 47.80  ? 330 THR C C     1 
ATOM   10698 O  O     . THR C 1 330 ? -24.908 30.747  -68.491  1.00 51.84  ? 330 THR C O     1 
ATOM   10699 C  CB    . THR C 1 330 ? -26.398 32.181  -65.949  1.00 54.91  ? 330 THR C CB    1 
ATOM   10700 O  OG1   . THR C 1 330 ? -27.153 33.318  -65.553  1.00 51.29  ? 330 THR C OG1   1 
ATOM   10701 C  CG2   . THR C 1 330 ? -24.937 32.537  -65.786  1.00 56.07  ? 330 THR C CG2   1 
ATOM   10702 N  N     . LEU C 1 331 ? -26.315 29.421  -67.341  1.00 46.73  ? 331 LEU C N     1 
ATOM   10703 C  CA    . LEU C 1 331 ? -25.608 28.198  -67.678  1.00 53.14  ? 331 LEU C CA    1 
ATOM   10704 C  C     . LEU C 1 331 ? -25.717 27.917  -69.181  1.00 53.71  ? 331 LEU C C     1 
ATOM   10705 O  O     . LEU C 1 331 ? -24.724 27.542  -69.818  1.00 44.28  ? 331 LEU C O     1 
ATOM   10706 C  CB    . LEU C 1 331 ? -26.165 27.052  -66.821  1.00 48.93  ? 331 LEU C CB    1 
ATOM   10707 C  CG    . LEU C 1 331 ? -26.040 27.228  -65.303  1.00 47.86  ? 331 LEU C CG    1 
ATOM   10708 C  CD1   . LEU C 1 331 ? -26.675 26.058  -64.579  1.00 51.47  ? 331 LEU C CD1   1 
ATOM   10709 C  CD2   . LEU C 1 331 ? -24.594 27.351  -64.874  1.00 50.55  ? 331 LEU C CD2   1 
ATOM   10710 N  N     . TRP C 1 332 ? -26.925 28.076  -69.741  1.00 50.68  ? 332 TRP C N     1 
ATOM   10711 C  CA    . TRP C 1 332 ? -27.136 27.769  -71.144  1.00 50.55  ? 332 TRP C CA    1 
ATOM   10712 C  C     . TRP C 1 332 ? -26.219 28.610  -72.030  1.00 47.71  ? 332 TRP C C     1 
ATOM   10713 O  O     . TRP C 1 332 ? -25.678 28.116  -73.013  1.00 49.69  ? 332 TRP C O     1 
ATOM   10714 C  CB    . TRP C 1 332 ? -28.596 27.982  -71.544  1.00 54.34  ? 332 TRP C CB    1 
ATOM   10715 C  CG    . TRP C 1 332 ? -28.767 27.852  -73.022  1.00 47.58  ? 332 TRP C CG    1 
ATOM   10716 C  CD1   . TRP C 1 332 ? -29.151 28.822  -73.901  1.00 52.90  ? 332 TRP C CD1   1 
ATOM   10717 C  CD2   . TRP C 1 332 ? -28.526 26.673  -73.801  1.00 44.90  ? 332 TRP C CD2   1 
ATOM   10718 N  NE1   . TRP C 1 332 ? -29.152 28.330  -75.179  1.00 47.95  ? 332 TRP C NE1   1 
ATOM   10719 C  CE2   . TRP C 1 332 ? -28.798 27.008  -75.146  1.00 43.99  ? 332 TRP C CE2   1 
ATOM   10720 C  CE3   . TRP C 1 332 ? -28.124 25.369  -73.497  1.00 47.70  ? 332 TRP C CE3   1 
ATOM   10721 C  CZ2   . TRP C 1 332 ? -28.652 26.087  -76.181  1.00 47.90  ? 332 TRP C CZ2   1 
ATOM   10722 C  CZ3   . TRP C 1 332 ? -27.973 24.462  -74.524  1.00 47.40  ? 332 TRP C CZ3   1 
ATOM   10723 C  CH2   . TRP C 1 332 ? -28.244 24.814  -75.845  1.00 48.19  ? 332 TRP C CH2   1 
ATOM   10724 N  N     . THR C 1 333 ? -26.093 29.894  -71.692  1.00 45.60  ? 333 THR C N     1 
ATOM   10725 C  CA    . THR C 1 333 ? -25.203 30.796  -72.388  1.00 50.74  ? 333 THR C CA    1 
ATOM   10726 C  C     . THR C 1 333 ? -23.802 30.218  -72.486  1.00 48.49  ? 333 THR C C     1 
ATOM   10727 O  O     . THR C 1 333 ? -23.193 30.244  -73.551  1.00 45.80  ? 333 THR C O     1 
ATOM   10728 C  CB    . THR C 1 333 ? -25.100 32.134  -71.659  1.00 52.82  ? 333 THR C CB    1 
ATOM   10729 O  OG1   . THR C 1 333 ? -26.406 32.695  -71.693  1.00 57.52  ? 333 THR C OG1   1 
ATOM   10730 C  CG2   . THR C 1 333 ? -24.108 33.078  -72.291  1.00 50.47  ? 333 THR C CG2   1 
ATOM   10731 N  N     . ALA C 1 334 ? -23.262 29.779  -71.347  1.00 45.97  ? 334 ALA C N     1 
ATOM   10732 C  CA    . ALA C 1 334 ? -21.906 29.261  -71.337  1.00 43.14  ? 334 ALA C CA    1 
ATOM   10733 C  C     . ALA C 1 334 ? -21.846 27.970  -72.151  1.00 45.78  ? 334 ALA C C     1 
ATOM   10734 O  O     . ALA C 1 334 ? -20.862 27.698  -72.835  1.00 43.75  ? 334 ALA C O     1 
ATOM   10735 C  CB    . ALA C 1 334 ? -21.469 29.057  -69.911  1.00 46.31  ? 334 ALA C CB    1 
ATOM   10736 N  N     . ILE C 1 335 ? -22.902 27.150  -72.088  1.00 43.33  ? 335 ILE C N     1 
ATOM   10737 C  CA    . ILE C 1 335 ? -22.858 25.885  -72.803  1.00 48.60  ? 335 ILE C CA    1 
ATOM   10738 C  C     . ILE C 1 335 ? -22.900 26.169  -74.303  1.00 51.93  ? 335 ILE C C     1 
ATOM   10739 O  O     . ILE C 1 335 ? -22.050 25.673  -75.059  1.00 47.83  ? 335 ILE C O     1 
ATOM   10740 C  CB    . ILE C 1 335 ? -23.974 24.927  -72.344  1.00 46.26  ? 335 ILE C CB    1 
ATOM   10741 C  CG1   . ILE C 1 335 ? -23.725 24.454  -70.908  1.00 43.03  ? 335 ILE C CG1   1 
ATOM   10742 C  CG2   . ILE C 1 335 ? -24.118 23.759  -73.313  1.00 44.68  ? 335 ILE C CG2   1 
ATOM   10743 C  CD1   . ILE C 1 335 ? -24.953 23.930  -70.203  1.00 45.67  ? 335 ILE C CD1   1 
ATOM   10744 N  N     . ARG C 1 336 ? -23.871 27.004  -74.696  1.00 50.19  ? 336 ARG C N     1 
ATOM   10745 C  CA    . ARG C 1 336 ? -24.124 27.322  -76.089  1.00 53.28  ? 336 ARG C CA    1 
ATOM   10746 C  C     . ARG C 1 336 ? -22.911 28.007  -76.714  1.00 47.99  ? 336 ARG C C     1 
ATOM   10747 O  O     . ARG C 1 336 ? -22.445 27.597  -77.769  1.00 50.92  ? 336 ARG C O     1 
ATOM   10748 C  CB    . ARG C 1 336 ? -25.363 28.212  -76.241  1.00 55.34  ? 336 ARG C CB    1 
ATOM   10749 C  CG    . ARG C 1 336 ? -25.679 28.551  -77.691  1.00 56.81  ? 336 ARG C CG    1 
ATOM   10750 C  CD    . ARG C 1 336 ? -27.010 29.232  -77.959  1.00 66.07  ? 336 ARG C CD    1 
ATOM   10751 N  NE    . ARG C 1 336 ? -27.049 29.613  -79.372  1.00 76.11  ? 336 ARG C NE    1 
ATOM   10752 C  CZ    . ARG C 1 336 ? -27.870 29.112  -80.295  1.00 80.60  ? 336 ARG C CZ    1 
ATOM   10753 N  NH1   . ARG C 1 336 ? -28.919 28.384  -79.948  1.00 88.66  ? 336 ARG C NH1   1 
ATOM   10754 N  NH2   . ARG C 1 336 ? -27.666 29.384  -81.573  1.00 77.49  ? 336 ARG C NH2   1 
ATOM   10755 N  N     . ASP C 1 337 ? -22.363 29.023  -76.054  1.00 50.95  ? 337 ASP C N     1 
ATOM   10756 C  CA    . ASP C 1 337 ? -21.218 29.722  -76.620  1.00 51.22  ? 337 ASP C CA    1 
ATOM   10757 C  C     . ASP C 1 337 ? -19.988 28.822  -76.739  1.00 52.39  ? 337 ASP C C     1 
ATOM   10758 O  O     . ASP C 1 337 ? -19.077 29.175  -77.477  1.00 52.98  ? 337 ASP C O     1 
ATOM   10759 C  CB    . ASP C 1 337 ? -20.874 30.962  -75.815  1.00 49.24  ? 337 ASP C CB    1 
ATOM   10760 C  CG    . ASP C 1 337 ? -21.972 32.005  -75.814  1.00 53.16  ? 337 ASP C CG    1 
ATOM   10761 O  OD1   . ASP C 1 337 ? -22.968 31.828  -76.572  1.00 54.55  ? 337 ASP C OD1   1 
ATOM   10762 O  OD2   . ASP C 1 337 ? -21.827 32.981  -75.050  1.00 55.98  ? 337 ASP C OD2   1 
ATOM   10763 N  N     . SER C 1 338 ? -19.953 27.686  -76.022  1.00 50.43  ? 338 SER C N     1 
ATOM   10764 C  CA    . SER C 1 338 ? -18.818 26.772  -76.082  1.00 51.22  ? 338 SER C CA    1 
ATOM   10765 C  C     . SER C 1 338 ? -18.774 26.027  -77.411  1.00 48.93  ? 338 SER C C     1 
ATOM   10766 O  O     . SER C 1 338 ? -17.722 25.513  -77.791  1.00 48.92  ? 338 SER C O     1 
ATOM   10767 C  CB    . SER C 1 338 ? -18.825 25.759  -74.955  1.00 47.88  ? 338 SER C CB    1 
ATOM   10768 O  OG    . SER C 1 338 ? -18.672 26.385  -73.693  1.00 50.65  ? 338 SER C OG    1 
ATOM   10769 N  N     . PHE C 1 339 ? -19.925 25.911  -78.076  1.00 43.52  ? 339 PHE C N     1 
ATOM   10770 C  CA    . PHE C 1 339 ? -20.048 25.004  -79.200  1.00 45.71  ? 339 PHE C CA    1 
ATOM   10771 C  C     . PHE C 1 339 ? -20.456 25.746  -80.466  1.00 50.27  ? 339 PHE C C     1 
ATOM   10772 O  O     . PHE C 1 339 ? -20.460 25.160  -81.547  1.00 49.59  ? 339 PHE C O     1 
ATOM   10773 C  CB    . PHE C 1 339 ? -21.062 23.905  -78.870  1.00 46.88  ? 339 PHE C CB    1 
ATOM   10774 C  CG    . PHE C 1 339 ? -20.610 22.983  -77.769  1.00 48.26  ? 339 PHE C CG    1 
ATOM   10775 C  CD1   . PHE C 1 339 ? -19.573 22.089  -77.979  1.00 46.07  ? 339 PHE C CD1   1 
ATOM   10776 C  CD2   . PHE C 1 339 ? -21.202 23.023  -76.521  1.00 49.21  ? 339 PHE C CD2   1 
ATOM   10777 C  CE1   . PHE C 1 339 ? -19.147 21.249  -76.964  1.00 47.24  ? 339 PHE C CE1   1 
ATOM   10778 C  CE2   . PHE C 1 339 ? -20.752 22.202  -75.501  1.00 48.17  ? 339 PHE C CE2   1 
ATOM   10779 C  CZ    . PHE C 1 339 ? -19.725 21.320  -75.723  1.00 46.65  ? 339 PHE C CZ    1 
ATOM   10780 N  N     . ALA C 1 340 ? -20.758 27.035  -80.327  1.00 49.68  ? 340 ALA C N     1 
ATOM   10781 C  CA    . ALA C 1 340 ? -21.478 27.753  -81.355  1.00 54.36  ? 340 ALA C CA    1 
ATOM   10782 C  C     . ALA C 1 340 ? -20.665 27.762  -82.647  1.00 59.73  ? 340 ALA C C     1 
ATOM   10783 O  O     . ALA C 1 340 ? -21.256 27.693  -83.716  1.00 69.72  ? 340 ALA C O     1 
ATOM   10784 C  CB    . ALA C 1 340 ? -21.790 29.148  -80.873  1.00 54.13  ? 340 ALA C CB    1 
ATOM   10785 N  N     . ASP C 1 341 ? -19.325 27.787  -82.539  1.00 60.14  ? 341 ASP C N     1 
ATOM   10786 C  CA    . ASP C 1 341 ? -18.462 28.011  -83.691  1.00 56.74  ? 341 ASP C CA    1 
ATOM   10787 C  C     . ASP C 1 341 ? -17.981 26.706  -84.321  1.00 54.51  ? 341 ASP C C     1 
ATOM   10788 O  O     . ASP C 1 341 ? -17.094 26.712  -85.173  1.00 55.02  ? 341 ASP C O     1 
ATOM   10789 C  CB    . ASP C 1 341 ? -17.237 28.850  -83.332  1.00 56.53  ? 341 ASP C CB    1 
ATOM   10790 C  CG    . ASP C 1 341 ? -16.261 28.190  -82.373  1.00 59.68  ? 341 ASP C CG    1 
ATOM   10791 O  OD1   . ASP C 1 341 ? -15.956 26.989  -82.526  1.00 62.06  ? 341 ASP C OD1   1 
ATOM   10792 O  OD2   . ASP C 1 341 ? -15.768 28.901  -81.515  1.00 68.35  ? 341 ASP C OD2   1 
ATOM   10793 N  N     . ILE C 1 342 ? -18.531 25.574  -83.907  1.00 51.06  ? 342 ILE C N     1 
ATOM   10794 C  CA    . ILE C 1 342 ? -18.196 24.339  -84.589  1.00 48.68  ? 342 ILE C CA    1 
ATOM   10795 C  C     . ILE C 1 342 ? -19.011 24.283  -85.873  1.00 52.62  ? 342 ILE C C     1 
ATOM   10796 O  O     . ILE C 1 342 ? -20.237 24.270  -85.813  1.00 58.46  ? 342 ILE C O     1 
ATOM   10797 C  CB    . ILE C 1 342 ? -18.461 23.117  -83.695  1.00 45.52  ? 342 ILE C CB    1 
ATOM   10798 C  CG1   . ILE C 1 342 ? -17.586 23.173  -82.438  1.00 48.40  ? 342 ILE C CG1   1 
ATOM   10799 C  CG2   . ILE C 1 342 ? -18.281 21.823  -84.485  1.00 44.96  ? 342 ILE C CG2   1 
ATOM   10800 C  CD1   . ILE C 1 342 ? -17.897 22.106  -81.398  1.00 50.67  ? 342 ILE C CD1   1 
ATOM   10801 N  N     . PRO C 1 343 ? -18.379 24.207  -87.066  1.00 54.14  ? 343 PRO C N     1 
ATOM   10802 C  CA    . PRO C 1 343 ? -19.143 24.159  -88.308  1.00 50.34  ? 343 PRO C CA    1 
ATOM   10803 C  C     . PRO C 1 343 ? -20.139 23.016  -88.187  1.00 51.50  ? 343 PRO C C     1 
ATOM   10804 O  O     . PRO C 1 343 ? -19.782 21.942  -87.705  1.00 53.96  ? 343 PRO C O     1 
ATOM   10805 C  CB    . PRO C 1 343 ? -18.121 23.881  -89.418  1.00 48.68  ? 343 PRO C CB    1 
ATOM   10806 C  CG    . PRO C 1 343 ? -16.771 24.205  -88.796  1.00 51.81  ? 343 PRO C CG    1 
ATOM   10807 C  CD    . PRO C 1 343 ? -16.930 24.097  -87.290  1.00 51.21  ? 343 PRO C CD    1 
ATOM   10808 N  N     . GLY C 1 344 ? -21.394 23.302  -88.553  1.00 52.46  ? 344 GLY C N     1 
ATOM   10809 C  CA    . GLY C 1 344 ? -22.420 22.288  -88.681  1.00 47.50  ? 344 GLY C CA    1 
ATOM   10810 C  C     . GLY C 1 344 ? -23.120 21.980  -87.366  1.00 46.98  ? 344 GLY C C     1 
ATOM   10811 O  O     . GLY C 1 344 ? -23.982 21.109  -87.325  1.00 49.90  ? 344 GLY C O     1 
ATOM   10812 N  N     . VAL C 1 345 ? -22.743 22.676  -86.290  1.00 52.52  ? 345 VAL C N     1 
ATOM   10813 C  CA    . VAL C 1 345 ? -23.376 22.445  -85.000  1.00 56.51  ? 345 VAL C CA    1 
ATOM   10814 C  C     . VAL C 1 345 ? -24.842 22.842  -85.111  1.00 54.13  ? 345 VAL C C     1 
ATOM   10815 O  O     . VAL C 1 345 ? -25.145 23.848  -85.744  1.00 58.90  ? 345 VAL C O     1 
ATOM   10816 C  CB    . VAL C 1 345 ? -22.692 23.224  -83.856  1.00 54.50  ? 345 VAL C CB    1 
ATOM   10817 C  CG1   . VAL C 1 345 ? -22.863 24.733  -83.971  1.00 47.62  ? 345 VAL C CG1   1 
ATOM   10818 C  CG2   . VAL C 1 345 ? -23.186 22.746  -82.504  1.00 55.01  ? 345 VAL C CG2   1 
ATOM   10819 N  N     . LYS C 1 346 ? -25.733 22.089  -84.453  1.00 54.64  ? 346 LYS C N     1 
ATOM   10820 C  CA    . LYS C 1 346 ? -27.100 22.561  -84.272  1.00 52.38  ? 346 LYS C CA    1 
ATOM   10821 C  C     . LYS C 1 346 ? -27.560 22.319  -82.836  1.00 56.70  ? 346 LYS C C     1 
ATOM   10822 O  O     . LYS C 1 346 ? -27.169 21.325  -82.211  1.00 56.93  ? 346 LYS C O     1 
ATOM   10823 C  CB    . LYS C 1 346 ? -28.048 21.879  -85.259  1.00 56.79  ? 346 LYS C CB    1 
ATOM   10824 C  CG    . LYS C 1 346 ? -27.733 22.130  -86.725  1.00 61.34  ? 346 LYS C CG    1 
ATOM   10825 C  CD    . LYS C 1 346 ? -28.722 21.471  -87.656  1.00 71.58  ? 346 LYS C CD    1 
ATOM   10826 C  CE    . LYS C 1 346 ? -28.389 21.687  -89.118  1.00 77.10  ? 346 LYS C CE    1 
ATOM   10827 N  NZ    . LYS C 1 346 ? -27.205 20.892  -89.534  1.00 77.91  ? 346 LYS C NZ    1 
ATOM   10828 N  N     . PHE C 1 347 ? -28.440 23.234  -82.393  1.00 50.52  ? 347 PHE C N     1 
ATOM   10829 C  CA    . PHE C 1 347 ? -28.957 23.373  -81.041  1.00 56.10  ? 347 PHE C CA    1 
ATOM   10830 C  C     . PHE C 1 347 ? -30.470 23.161  -81.043  1.00 54.71  ? 347 PHE C C     1 
ATOM   10831 O  O     . PHE C 1 347 ? -31.178 23.885  -81.730  1.00 53.63  ? 347 PHE C O     1 
ATOM   10832 C  CB    . PHE C 1 347 ? -28.664 24.791  -80.539  1.00 56.07  ? 347 PHE C CB    1 
ATOM   10833 C  CG    . PHE C 1 347 ? -27.198 25.118  -80.439  1.00 55.44  ? 347 PHE C CG    1 
ATOM   10834 C  CD1   . PHE C 1 347 ? -26.451 24.681  -79.355  1.00 52.59  ? 347 PHE C CD1   1 
ATOM   10835 C  CD2   . PHE C 1 347 ? -26.556 25.808  -81.453  1.00 56.93  ? 347 PHE C CD2   1 
ATOM   10836 C  CE1   . PHE C 1 347 ? -25.099 24.953  -79.267  1.00 47.17  ? 347 PHE C CE1   1 
ATOM   10837 C  CE2   . PHE C 1 347 ? -25.198 26.081  -81.366  1.00 53.68  ? 347 PHE C CE2   1 
ATOM   10838 C  CZ    . PHE C 1 347 ? -24.474 25.649  -80.275  1.00 54.15  ? 347 PHE C CZ    1 
ATOM   10839 N  N     . TYR C 1 348 ? -30.950 22.197  -80.249  1.00 57.25  ? 348 TYR C N     1 
ATOM   10840 C  CA    . TYR C 1 348 ? -32.362 21.859  -80.187  1.00 56.00  ? 348 TYR C CA    1 
ATOM   10841 C  C     . TYR C 1 348 ? -32.840 21.837  -78.739  1.00 63.36  ? 348 TYR C C     1 
ATOM   10842 O  O     . TYR C 1 348 ? -32.223 21.180  -77.885  1.00 51.75  ? 348 TYR C O     1 
ATOM   10843 C  CB    . TYR C 1 348 ? -32.643 20.481  -80.796  1.00 55.42  ? 348 TYR C CB    1 
ATOM   10844 C  CG    . TYR C 1 348 ? -32.252 20.324  -82.247  1.00 62.03  ? 348 TYR C CG    1 
ATOM   10845 C  CD1   . TYR C 1 348 ? -30.976 19.908  -82.601  1.00 55.02  ? 348 TYR C CD1   1 
ATOM   10846 C  CD2   . TYR C 1 348 ? -33.143 20.619  -83.270  1.00 58.68  ? 348 TYR C CD2   1 
ATOM   10847 C  CE1   . TYR C 1 348 ? -30.597 19.766  -83.925  1.00 58.75  ? 348 TYR C CE1   1 
ATOM   10848 C  CE2   . TYR C 1 348 ? -32.777 20.500  -84.603  1.00 61.78  ? 348 TYR C CE2   1 
ATOM   10849 C  CZ    . TYR C 1 348 ? -31.501 20.065  -84.931  1.00 63.80  ? 348 TYR C CZ    1 
ATOM   10850 O  OH    . TYR C 1 348 ? -31.121 19.929  -86.242  1.00 60.04  ? 348 TYR C OH    1 
ATOM   10851 N  N     . PHE C 1 349 ? -33.933 22.578  -78.488  1.00 59.40  ? 349 PHE C N     1 
ATOM   10852 C  CA    . PHE C 1 349 ? -34.794 22.345  -77.337  1.00 61.10  ? 349 PHE C CA    1 
ATOM   10853 C  C     . PHE C 1 349 ? -35.948 21.453  -77.808  1.00 61.83  ? 349 PHE C C     1 
ATOM   10854 O  O     . PHE C 1 349 ? -36.117 21.246  -79.009  1.00 55.27  ? 349 PHE C O     1 
ATOM   10855 C  CB    . PHE C 1 349 ? -35.205 23.685  -76.710  1.00 64.84  ? 349 PHE C CB    1 
ATOM   10856 C  CG    . PHE C 1 349 ? -34.118 24.387  -75.928  1.00 63.72  ? 349 PHE C CG    1 
ATOM   10857 C  CD1   . PHE C 1 349 ? -33.580 23.812  -74.783  1.00 64.05  ? 349 PHE C CD1   1 
ATOM   10858 C  CD2   . PHE C 1 349 ? -33.638 25.629  -76.321  1.00 70.24  ? 349 PHE C CD2   1 
ATOM   10859 C  CE1   . PHE C 1 349 ? -32.575 24.446  -74.063  1.00 69.22  ? 349 PHE C CE1   1 
ATOM   10860 C  CE2   . PHE C 1 349 ? -32.633 26.264  -75.599  1.00 69.14  ? 349 PHE C CE2   1 
ATOM   10861 C  CZ    . PHE C 1 349 ? -32.101 25.672  -74.474  1.00 67.00  ? 349 PHE C CZ    1 
ATOM   10862 N  N     . PRO C 1 350 ? -36.752 20.850  -76.906  1.00 62.98  ? 350 PRO C N     1 
ATOM   10863 C  CA    . PRO C 1 350 ? -37.781 19.885  -77.316  1.00 64.72  ? 350 PRO C CA    1 
ATOM   10864 C  C     . PRO C 1 350 ? -38.767 20.434  -78.351  1.00 63.27  ? 350 PRO C C     1 
ATOM   10865 O  O     . PRO C 1 350 ? -39.217 19.704  -79.226  1.00 66.34  ? 350 PRO C O     1 
ATOM   10866 C  CB    . PRO C 1 350 ? -38.506 19.536  -76.006  1.00 62.80  ? 350 PRO C CB    1 
ATOM   10867 C  CG    . PRO C 1 350 ? -37.516 19.889  -74.911  1.00 60.02  ? 350 PRO C CG    1 
ATOM   10868 C  CD    . PRO C 1 350 ? -36.741 21.073  -75.452  1.00 65.21  ? 350 PRO C CD    1 
ATOM   10869 N  N     . GLU C 1 351 ? -39.038 21.741  -78.280  1.00 67.70  ? 351 GLU C N     1 
ATOM   10870 C  CA    . GLU C 1 351 ? -39.953 22.411  -79.190  1.00 72.61  ? 351 GLU C CA    1 
ATOM   10871 C  C     . GLU C 1 351 ? -39.359 22.521  -80.593  1.00 72.30  ? 351 GLU C C     1 
ATOM   10872 O  O     . GLU C 1 351 ? -40.107 22.664  -81.555  1.00 65.64  ? 351 GLU C O     1 
ATOM   10873 C  CB    . GLU C 1 351 ? -40.339 23.803  -78.672  1.00 69.93  ? 351 GLU C CB    1 
ATOM   10874 C  CG    . GLU C 1 351 ? -39.172 24.755  -78.411  1.00 71.54  ? 351 GLU C CG    1 
ATOM   10875 C  CD    . GLU C 1 351 ? -38.589 24.760  -77.001  1.00 69.30  ? 351 GLU C CD    1 
ATOM   10876 O  OE1   . GLU C 1 351 ? -38.752 23.753  -76.277  1.00 55.12  ? 351 GLU C OE1   1 
ATOM   10877 O  OE2   . GLU C 1 351 ? -37.989 25.786  -76.616  1.00 68.32  ? 351 GLU C OE2   1 
ATOM   10878 N  N     . ASP C 1 352 ? -38.026 22.477  -80.713  1.00 63.73  ? 352 ASP C N     1 
ATOM   10879 C  CA    . ASP C 1 352 ? -37.370 22.687  -81.989  1.00 57.32  ? 352 ASP C CA    1 
ATOM   10880 C  C     . ASP C 1 352 ? -37.235 21.370  -82.748  1.00 61.04  ? 352 ASP C C     1 
ATOM   10881 O  O     . ASP C 1 352 ? -36.679 21.378  -83.840  1.00 64.43  ? 352 ASP C O     1 
ATOM   10882 C  CB    . ASP C 1 352 ? -35.992 23.324  -81.801  1.00 66.72  ? 352 ASP C CB    1 
ATOM   10883 C  CG    . ASP C 1 352 ? -36.027 24.524  -80.878  1.00 71.85  ? 352 ASP C CG    1 
ATOM   10884 O  OD1   . ASP C 1 352 ? -36.793 25.455  -81.181  1.00 64.16  ? 352 ASP C OD1   1 
ATOM   10885 O  OD2   . ASP C 1 352 ? -35.311 24.499  -79.850  1.00 74.29  ? 352 ASP C OD2   1 
ATOM   10886 N  N     . ARG C 1 353 ? -37.726 20.254  -82.183  1.00 57.80  ? 353 ARG C N     1 
ATOM   10887 C  CA    . ARG C 1 353 ? -37.663 18.956  -82.845  1.00 64.81  ? 353 ARG C CA    1 
ATOM   10888 C  C     . ARG C 1 353 ? -38.929 18.721  -83.674  1.00 79.25  ? 353 ARG C C     1 
ATOM   10889 O  O     . ARG C 1 353 ? -40.022 18.592  -83.125  1.00 80.58  ? 353 ARG C O     1 
ATOM   10890 C  CB    . ARG C 1 353 ? -37.538 17.828  -81.815  1.00 60.11  ? 353 ARG C CB    1 
ATOM   10891 C  CG    . ARG C 1 353 ? -36.401 18.029  -80.825  1.00 62.47  ? 353 ARG C CG    1 
ATOM   10892 C  CD    . ARG C 1 353 ? -35.071 18.002  -81.544  1.00 54.71  ? 353 ARG C CD    1 
ATOM   10893 N  NE    . ARG C 1 353 ? -34.812 16.660  -82.028  1.00 54.50  ? 353 ARG C NE    1 
ATOM   10894 C  CZ    . ARG C 1 353 ? -33.912 16.355  -82.951  1.00 52.22  ? 353 ARG C CZ    1 
ATOM   10895 N  NH1   . ARG C 1 353 ? -33.224 17.304  -83.564  1.00 55.39  ? 353 ARG C NH1   1 
ATOM   10896 N  NH2   . ARG C 1 353 ? -33.723 15.088  -83.269  1.00 53.57  ? 353 ARG C NH2   1 
ATOM   10897 N  N     . ARG C 1 354 ? -38.765 18.606  -84.996  1.00 84.46  ? 354 ARG C N     1 
ATOM   10898 C  CA    . ARG C 1 354 ? -39.896 18.422  -85.890  1.00 81.60  ? 354 ARG C CA    1 
ATOM   10899 C  C     . ARG C 1 354 ? -40.576 17.073  -85.639  1.00 75.29  ? 354 ARG C C     1 
ATOM   10900 O  O     . ARG C 1 354 ? -41.778 16.979  -85.842  1.00 82.83  ? 354 ARG C O     1 
ATOM   10901 C  CB    . ARG C 1 354 ? -39.485 18.656  -87.350  1.00 79.35  ? 354 ARG C CB    1 
ATOM   10902 C  CG    . ARG C 1 354 ? -38.414 17.732  -87.911  1.00 81.22  ? 354 ARG C CG    1 
ATOM   10903 C  CD    . ARG C 1 354 ? -38.099 18.140  -89.345  1.00 81.26  ? 354 ARG C CD    1 
ATOM   10904 N  NE    . ARG C 1 354 ? -36.997 17.405  -89.964  1.00 84.52  ? 354 ARG C NE    1 
ATOM   10905 C  CZ    . ARG C 1 354 ? -37.077 16.187  -90.504  1.00 84.79  ? 354 ARG C CZ    1 
ATOM   10906 N  NH1   . ARG C 1 354 ? -38.238 15.563  -90.611  1.00 81.35  ? 354 ARG C NH1   1 
ATOM   10907 N  NH2   . ARG C 1 354 ? -35.987 15.598  -90.964  1.00 85.41  ? 354 ARG C NH2   1 
ATOM   10908 N  N     . HIS C 1 355 ? -39.855 16.039  -85.180  1.00 65.98  ? 355 HIS C N     1 
ATOM   10909 C  CA    . HIS C 1 355 ? -40.510 14.780  -84.841  1.00 67.58  ? 355 HIS C CA    1 
ATOM   10910 C  C     . HIS C 1 355 ? -41.073 14.860  -83.412  1.00 81.48  ? 355 HIS C C     1 
ATOM   10911 O  O     . HIS C 1 355 ? -40.642 15.697  -82.617  1.00 82.42  ? 355 HIS C O     1 
ATOM   10912 C  CB    . HIS C 1 355 ? -39.571 13.581  -85.030  1.00 64.71  ? 355 HIS C CB    1 
ATOM   10913 C  CG    . HIS C 1 355 ? -38.841 13.476  -86.337  1.00 71.37  ? 355 HIS C CG    1 
ATOM   10914 N  ND1   . HIS C 1 355 ? -39.134 12.505  -87.278  1.00 74.86  ? 355 HIS C ND1   1 
ATOM   10915 C  CD2   . HIS C 1 355 ? -37.813 14.182  -86.853  1.00 74.42  ? 355 HIS C CD2   1 
ATOM   10916 C  CE1   . HIS C 1 355 ? -38.317 12.634  -88.320  1.00 69.16  ? 355 HIS C CE1   1 
ATOM   10917 N  NE2   . HIS C 1 355 ? -37.501 13.643  -88.082  1.00 72.99  ? 355 HIS C NE2   1 
ATOM   10918 N  N     . LYS C 1 356 ? -42.061 14.003  -83.089  1.00 81.63  ? 356 LYS C N     1 
ATOM   10919 C  CA    . LYS C 1 356 ? -42.599 13.913  -81.734  1.00 75.79  ? 356 LYS C CA    1 
ATOM   10920 C  C     . LYS C 1 356 ? -41.918 12.741  -81.034  1.00 69.86  ? 356 LYS C C     1 
ATOM   10921 O  O     . LYS C 1 356 ? -41.205 12.963  -80.070  1.00 90.81  ? 356 LYS C O     1 
ATOM   10922 C  CB    . LYS C 1 356 ? -44.126 13.735  -81.654  1.00 83.71  ? 356 LYS C CB    1 
ATOM   10923 C  CG    . LYS C 1 356 ? -45.014 14.719  -82.422  1.00 90.66  ? 356 LYS C CG    1 
ATOM   10924 C  CD    . LYS C 1 356 ? -46.523 14.541  -82.146  1.00 91.67  ? 356 LYS C CD    1 
ATOM   10925 C  CE    . LYS C 1 356 ? -47.427 14.671  -83.359  1.00 95.62  ? 356 LYS C CE    1 
ATOM   10926 N  NZ    . LYS C 1 356 ? -47.429 16.034  -83.935  1.00 94.33  ? 356 LYS C NZ    1 
ATOM   10927 N  N     . VAL C 1 357 ? -42.121 11.504  -81.513  1.00 72.22  ? 357 VAL C N     1 
ATOM   10928 C  CA    . VAL C 1 357 ? -41.205 10.410  -81.208  1.00 72.70  ? 357 VAL C CA    1 
ATOM   10929 C  C     . VAL C 1 357 ? -39.824 10.842  -81.718  1.00 79.56  ? 357 VAL C C     1 
ATOM   10930 O  O     . VAL C 1 357 ? -39.659 11.139  -82.903  1.00 67.38  ? 357 VAL C O     1 
ATOM   10931 C  CB    . VAL C 1 357 ? -41.648 9.058   -81.817  1.00 74.27  ? 357 VAL C CB    1 
ATOM   10932 C  CG1   . VAL C 1 357 ? -40.654 7.931   -81.556  1.00 70.97  ? 357 VAL C CG1   1 
ATOM   10933 C  CG2   . VAL C 1 357 ? -43.035 8.631   -81.356  1.00 77.59  ? 357 VAL C CG2   1 
ATOM   10934 N  N     . ASP C 1 358 ? -38.839 10.891  -80.805  1.00 83.57  ? 358 ASP C N     1 
ATOM   10935 C  CA    . ASP C 1 358 ? -37.643 11.706  -80.973  1.00 70.50  ? 358 ASP C CA    1 
ATOM   10936 C  C     . ASP C 1 358 ? -36.656 11.417  -79.842  1.00 68.87  ? 358 ASP C C     1 
ATOM   10937 O  O     . ASP C 1 358 ? -37.060 11.316  -78.683  1.00 55.55  ? 358 ASP C O     1 
ATOM   10938 C  CB    . ASP C 1 358 ? -38.014 13.188  -80.961  1.00 76.30  ? 358 ASP C CB    1 
ATOM   10939 C  CG    . ASP C 1 358 ? -36.880 14.120  -81.339  1.00 73.09  ? 358 ASP C CG    1 
ATOM   10940 O  OD1   . ASP C 1 358 ? -36.385 14.005  -82.474  1.00 59.75  ? 358 ASP C OD1   1 
ATOM   10941 O  OD2   . ASP C 1 358 ? -36.548 14.990  -80.518  1.00 78.05  ? 358 ASP C OD2   1 
ATOM   10942 N  N     . LEU C 1 359 ? -35.361 11.302  -80.185  1.00 60.14  ? 359 LEU C N     1 
ATOM   10943 C  CA    . LEU C 1 359 ? -34.317 11.050  -79.208  1.00 51.19  ? 359 LEU C CA    1 
ATOM   10944 C  C     . LEU C 1 359 ? -34.401 12.051  -78.058  1.00 44.06  ? 359 LEU C C     1 
ATOM   10945 O  O     . LEU C 1 359 ? -34.371 11.664  -76.886  1.00 42.16  ? 359 LEU C O     1 
ATOM   10946 C  CB    . LEU C 1 359 ? -32.947 11.171  -79.882  1.00 58.96  ? 359 LEU C CB    1 
ATOM   10947 C  CG    . LEU C 1 359 ? -31.785 11.249  -78.889  1.00 65.80  ? 359 LEU C CG    1 
ATOM   10948 C  CD1   . LEU C 1 359 ? -31.392 9.857   -78.430  1.00 67.49  ? 359 LEU C CD1   1 
ATOM   10949 C  CD2   . LEU C 1 359 ? -30.603 12.011  -79.469  1.00 71.52  ? 359 LEU C CD2   1 
ATOM   10950 N  N     . LEU C 1 360 ? -34.467 13.350  -78.402  1.00 43.73  ? 360 LEU C N     1 
ATOM   10951 C  CA    . LEU C 1 360 ? -34.424 14.365  -77.371  1.00 43.97  ? 360 LEU C CA    1 
ATOM   10952 C  C     . LEU C 1 360 ? -35.568 14.104  -76.408  1.00 50.95  ? 360 LEU C C     1 
ATOM   10953 O  O     . LEU C 1 360 ? -35.346 14.024  -75.210  1.00 60.93  ? 360 LEU C O     1 
ATOM   10954 C  CB    . LEU C 1 360 ? -34.487 15.779  -77.965  1.00 43.83  ? 360 LEU C CB    1 
ATOM   10955 C  CG    . LEU C 1 360 ? -34.578 16.925  -76.952  1.00 46.59  ? 360 LEU C CG    1 
ATOM   10956 C  CD1   . LEU C 1 360 ? -33.594 16.756  -75.792  1.00 53.08  ? 360 LEU C CD1   1 
ATOM   10957 C  CD2   . LEU C 1 360 ? -34.341 18.273  -77.622  1.00 48.51  ? 360 LEU C CD2   1 
ATOM   10958 N  N     . LEU C 1 361 ? -36.779 13.925  -76.938  1.00 46.10  ? 361 LEU C N     1 
ATOM   10959 C  CA    . LEU C 1 361 ? -37.941 13.803  -76.074  1.00 48.90  ? 361 LEU C CA    1 
ATOM   10960 C  C     . LEU C 1 361 ? -37.858 12.554  -75.211  1.00 42.72  ? 361 LEU C C     1 
ATOM   10961 O  O     . LEU C 1 361 ? -38.257 12.589  -74.061  1.00 46.94  ? 361 LEU C O     1 
ATOM   10962 C  CB    . LEU C 1 361 ? -39.203 13.838  -76.934  1.00 52.94  ? 361 LEU C CB    1 
ATOM   10963 C  CG    . LEU C 1 361 ? -39.450 15.211  -77.542  1.00 60.87  ? 361 LEU C CG    1 
ATOM   10964 C  CD1   . LEU C 1 361 ? -40.531 15.172  -78.614  1.00 69.21  ? 361 LEU C CD1   1 
ATOM   10965 C  CD2   . LEU C 1 361 ? -39.801 16.197  -76.443  1.00 65.02  ? 361 LEU C CD2   1 
ATOM   10966 N  N     . HIS C 1 362 ? -37.306 11.459  -75.727  1.00 42.37  ? 362 HIS C N     1 
ATOM   10967 C  CA    . HIS C 1 362 ? -37.105 10.304  -74.876  1.00 47.61  ? 362 HIS C CA    1 
ATOM   10968 C  C     . HIS C 1 362 ? -36.071 10.609  -73.775  1.00 50.87  ? 362 HIS C C     1 
ATOM   10969 O  O     . HIS C 1 362 ? -36.264 10.280  -72.601  1.00 50.19  ? 362 HIS C O     1 
ATOM   10970 C  CB    . HIS C 1 362 ? -36.767 9.086   -75.728  1.00 50.47  ? 362 HIS C CB    1 
ATOM   10971 C  CG    . HIS C 1 362 ? -36.020 8.071   -74.945  1.00 59.35  ? 362 HIS C CG    1 
ATOM   10972 N  ND1   . HIS C 1 362 ? -36.520 7.546   -73.776  1.00 63.26  ? 362 HIS C ND1   1 
ATOM   10973 C  CD2   . HIS C 1 362 ? -34.795 7.540   -75.107  1.00 69.36  ? 362 HIS C CD2   1 
ATOM   10974 C  CE1   . HIS C 1 362 ? -35.627 6.707   -73.266  1.00 66.89  ? 362 HIS C CE1   1 
ATOM   10975 N  NE2   . HIS C 1 362 ? -34.581 6.671   -74.070  1.00 67.93  ? 362 HIS C NE2   1 
ATOM   10976 N  N     . ARG C 1 363 ? -34.957 11.243  -74.139  1.00 52.15  ? 363 ARG C N     1 
ATOM   10977 C  CA    . ARG C 1 363 ? -33.908 11.509  -73.155  1.00 55.71  ? 363 ARG C CA    1 
ATOM   10978 C  C     . ARG C 1 363 ? -34.330 12.610  -72.179  1.00 52.69  ? 363 ARG C C     1 
ATOM   10979 O  O     . ARG C 1 363 ? -33.939 12.590  -71.015  1.00 49.77  ? 363 ARG C O     1 
ATOM   10980 C  CB    . ARG C 1 363 ? -32.577 11.752  -73.867  1.00 51.55  ? 363 ARG C CB    1 
ATOM   10981 C  CG    . ARG C 1 363 ? -32.138 10.516  -74.642  1.00 51.73  ? 363 ARG C CG    1 
ATOM   10982 C  CD    . ARG C 1 363 ? -30.726 10.051  -74.391  1.00 59.25  ? 363 ARG C CD    1 
ATOM   10983 N  NE    . ARG C 1 363 ? -30.306 10.137  -72.998  1.00 58.62  ? 363 ARG C NE    1 
ATOM   10984 C  CZ    . ARG C 1 363 ? -30.088 9.107   -72.198  1.00 57.99  ? 363 ARG C CZ    1 
ATOM   10985 N  NH1   . ARG C 1 363 ? -30.609 7.923   -72.474  1.00 52.95  ? 363 ARG C NH1   1 
ATOM   10986 N  NH2   . ARG C 1 363 ? -29.389 9.291   -71.090  1.00 62.27  ? 363 ARG C NH2   1 
ATOM   10987 N  N     . ALA C 1 364 ? -35.203 13.513  -72.617  1.00 52.28  ? 364 ALA C N     1 
ATOM   10988 C  CA    . ALA C 1 364 ? -35.703 14.557  -71.744  1.00 48.12  ? 364 ALA C CA    1 
ATOM   10989 C  C     . ALA C 1 364 ? -36.408 13.948  -70.533  1.00 53.28  ? 364 ALA C C     1 
ATOM   10990 O  O     . ALA C 1 364 ? -36.500 14.562  -69.470  1.00 55.92  ? 364 ALA C O     1 
ATOM   10991 C  CB    . ALA C 1 364 ? -36.623 15.462  -72.510  1.00 47.02  ? 364 ALA C CB    1 
ATOM   10992 N  N     . GLU C 1 365 ? -36.922 12.732  -70.679  1.00 51.23  ? 365 GLU C N     1 
ATOM   10993 C  CA    . GLU C 1 365 ? -37.547 12.089  -69.536  1.00 54.69  ? 365 GLU C CA    1 
ATOM   10994 C  C     . GLU C 1 365 ? -36.525 11.362  -68.659  1.00 47.73  ? 365 GLU C C     1 
ATOM   10995 O  O     . GLU C 1 365 ? -36.600 11.440  -67.439  1.00 45.48  ? 365 GLU C O     1 
ATOM   10996 C  CB    . GLU C 1 365 ? -38.663 11.194  -70.054  1.00 62.76  ? 365 GLU C CB    1 
ATOM   10997 C  CG    . GLU C 1 365 ? -39.755 12.014  -70.706  1.00 64.98  ? 365 GLU C CG    1 
ATOM   10998 C  CD    . GLU C 1 365 ? -41.114 11.422  -70.430  1.00 78.99  ? 365 GLU C CD    1 
ATOM   10999 O  OE1   . GLU C 1 365 ? -41.864 12.053  -69.658  1.00 89.99  ? 365 GLU C OE1   1 
ATOM   11000 O  OE2   . GLU C 1 365 ? -41.385 10.313  -70.956  1.00 87.82  ? 365 GLU C OE2   1 
ATOM   11001 N  N     . THR C 1 366 ? -35.581 10.644  -69.272  1.00 43.13  ? 366 THR C N     1 
ATOM   11002 C  CA    . THR C 1 366 ? -34.498 10.013  -68.535  1.00 49.47  ? 366 THR C CA    1 
ATOM   11003 C  C     . THR C 1 366 ? -33.806 11.048  -67.631  1.00 45.51  ? 366 THR C C     1 
ATOM   11004 O  O     . THR C 1 366 ? -33.554 10.781  -66.461  1.00 39.36  ? 366 THR C O     1 
ATOM   11005 C  CB    . THR C 1 366 ? -33.534 9.304   -69.498  1.00 50.55  ? 366 THR C CB    1 
ATOM   11006 O  OG1   . THR C 1 366 ? -34.296 8.561   -70.461  1.00 49.24  ? 366 THR C OG1   1 
ATOM   11007 C  CG2   . THR C 1 366 ? -32.592 8.363   -68.767  1.00 49.93  ? 366 THR C CG2   1 
ATOM   11008 N  N     . MET C 1 367 ? -33.591 12.260  -68.158  1.00 43.60  ? 367 MET C N     1 
ATOM   11009 C  CA    . MET C 1 367 ? -32.790 13.269  -67.490  1.00 45.36  ? 367 MET C CA    1 
ATOM   11010 C  C     . MET C 1 367 ? -33.608 14.026  -66.447  1.00 46.02  ? 367 MET C C     1 
ATOM   11011 O  O     . MET C 1 367 ? -33.070 14.905  -65.772  1.00 44.20  ? 367 MET C O     1 
ATOM   11012 C  CB    . MET C 1 367 ? -32.180 14.226  -68.518  1.00 42.94  ? 367 MET C CB    1 
ATOM   11013 C  CG    . MET C 1 367 ? -31.096 13.550  -69.356  1.00 41.89  ? 367 MET C CG    1 
ATOM   11014 S  SD    . MET C 1 367 ? -30.228 14.640  -70.517  1.00 46.62  ? 367 MET C SD    1 
ATOM   11015 C  CE    . MET C 1 367 ? -31.561 15.380  -71.461  1.00 52.40  ? 367 MET C CE    1 
ATOM   11016 N  N     . LYS C 1 368 ? -34.879 13.643  -66.235  1.00 51.05  ? 368 LYS C N     1 
ATOM   11017 C  CA    . LYS C 1 368 ? -35.563 14.068  -65.016  1.00 52.00  ? 368 LYS C CA    1 
ATOM   11018 C  C     . LYS C 1 368 ? -35.965 12.865  -64.161  1.00 44.08  ? 368 LYS C C     1 
ATOM   11019 O  O     . LYS C 1 368 ? -36.682 13.013  -63.177  1.00 51.76  ? 368 LYS C O     1 
ATOM   11020 C  CB    . LYS C 1 368 ? -36.725 15.029  -65.306  1.00 58.48  ? 368 LYS C CB    1 
ATOM   11021 C  CG    . LYS C 1 368 ? -37.889 14.504  -66.131  1.00 58.89  ? 368 LYS C CG    1 
ATOM   11022 C  CD    . LYS C 1 368 ? -38.944 15.572  -66.379  1.00 59.04  ? 368 LYS C CD    1 
ATOM   11023 C  CE    . LYS C 1 368 ? -40.091 15.063  -67.229  1.00 69.71  ? 368 LYS C CE    1 
ATOM   11024 N  NZ    . LYS C 1 368 ? -41.046 16.146  -67.564  1.00 73.86  ? 368 LYS C NZ    1 
ATOM   11025 N  N     . GLY C 1 369 ? -35.447 11.681  -64.481  1.00 41.64  ? 369 GLY C N     1 
ATOM   11026 C  CA    . GLY C 1 369 ? -35.560 10.547  -63.575  1.00 44.67  ? 369 GLY C CA    1 
ATOM   11027 C  C     . GLY C 1 369 ? -36.822 9.714   -63.789  1.00 41.55  ? 369 GLY C C     1 
ATOM   11028 O  O     . GLY C 1 369 ? -37.200 8.949   -62.907  1.00 44.46  ? 369 GLY C O     1 
ATOM   11029 N  N     . VAL C 1 370 ? -37.453 9.841   -64.963  1.00 41.88  ? 370 VAL C N     1 
ATOM   11030 C  CA    . VAL C 1 370 ? -38.597 9.013   -65.283  1.00 41.03  ? 370 VAL C CA    1 
ATOM   11031 C  C     . VAL C 1 370 ? -38.071 7.681   -65.825  1.00 42.85  ? 370 VAL C C     1 
ATOM   11032 O  O     . VAL C 1 370 ? -37.487 7.619   -66.914  1.00 43.96  ? 370 VAL C O     1 
ATOM   11033 C  CB    . VAL C 1 370 ? -39.555 9.697   -66.281  1.00 46.73  ? 370 VAL C CB    1 
ATOM   11034 C  CG1   . VAL C 1 370 ? -40.725 8.794   -66.630  1.00 45.04  ? 370 VAL C CG1   1 
ATOM   11035 C  CG2   . VAL C 1 370 ? -40.054 11.049  -65.785  1.00 49.85  ? 370 VAL C CG2   1 
ATOM   11036 N  N     . PRO C 1 371 ? -38.314 6.555   -65.125  1.00 37.42  ? 371 PRO C N     1 
ATOM   11037 C  CA    . PRO C 1 371 ? -37.832 5.250   -65.578  1.00 42.30  ? 371 PRO C CA    1 
ATOM   11038 C  C     . PRO C 1 371 ? -38.587 4.781   -66.807  1.00 48.47  ? 371 PRO C C     1 
ATOM   11039 O  O     . PRO C 1 371 ? -39.815 4.917   -66.856  1.00 44.95  ? 371 PRO C O     1 
ATOM   11040 C  CB    . PRO C 1 371 ? -38.177 4.278   -64.452  1.00 41.23  ? 371 PRO C CB    1 
ATOM   11041 C  CG    . PRO C 1 371 ? -39.360 4.956   -63.756  1.00 44.87  ? 371 PRO C CG    1 
ATOM   11042 C  CD    . PRO C 1 371 ? -39.150 6.450   -63.924  1.00 40.82  ? 371 PRO C CD    1 
ATOM   11043 N  N     . LYS C 1 372 ? -37.849 4.243   -67.785  1.00 48.48  ? 372 LYS C N     1 
ATOM   11044 C  CA    . LYS C 1 372 ? -38.476 3.794   -69.016  1.00 50.03  ? 372 LYS C CA    1 
ATOM   11045 C  C     . LYS C 1 372 ? -37.805 2.508   -69.478  1.00 50.03  ? 372 LYS C C     1 
ATOM   11046 O  O     . LYS C 1 372 ? -36.862 2.034   -68.837  1.00 46.84  ? 372 LYS C O     1 
ATOM   11047 C  CB    . LYS C 1 372 ? -38.436 4.940   -70.024  1.00 50.78  ? 372 LYS C CB    1 
ATOM   11048 C  CG    . LYS C 1 372 ? -39.499 6.007   -69.817  1.00 58.50  ? 372 LYS C CG    1 
ATOM   11049 C  CD    . LYS C 1 372 ? -39.172 7.329   -70.483  1.00 76.13  ? 372 LYS C CD    1 
ATOM   11050 C  CE    . LYS C 1 372 ? -38.674 7.239   -71.916  1.00 86.24  ? 372 LYS C CE    1 
ATOM   11051 N  NZ    . LYS C 1 372 ? -39.768 7.115   -72.912  1.00 89.89  ? 372 LYS C NZ    1 
ATOM   11052 N  N     . LEU C 1 373 ? -38.335 1.927   -70.566  1.00 53.81  ? 373 LEU C N     1 
ATOM   11053 C  CA    . LEU C 1 373 ? -37.755 0.726   -71.153  1.00 56.25  ? 373 LEU C CA    1 
ATOM   11054 C  C     . LEU C 1 373 ? -37.428 0.939   -72.633  1.00 52.09  ? 373 LEU C C     1 
ATOM   11055 O  O     . LEU C 1 373 ? -37.041 -0.014  -73.309  1.00 56.71  ? 373 LEU C O     1 
ATOM   11056 C  CB    . LEU C 1 373 ? -38.716 -0.457  -70.981  1.00 57.69  ? 373 LEU C CB    1 
ATOM   11057 C  CG    . LEU C 1 373 ? -38.645 -1.236  -69.671  1.00 63.09  ? 373 LEU C CG    1 
ATOM   11058 C  CD1   . LEU C 1 373 ? -39.644 -2.393  -69.689  1.00 65.69  ? 373 LEU C CD1   1 
ATOM   11059 C  CD2   . LEU C 1 373 ? -37.243 -1.762  -69.401  1.00 65.01  ? 373 LEU C CD2   1 
ATOM   11060 N  N     . THR C 1 374 ? -37.484 2.186   -73.113  1.00 50.31  ? 374 THR C N     1 
ATOM   11061 C  CA    . THR C 1 374 ? -37.449 2.438   -74.543  1.00 57.05  ? 374 THR C CA    1 
ATOM   11062 C  C     . THR C 1 374 ? -36.016 2.361   -75.094  1.00 60.50  ? 374 THR C C     1 
ATOM   11063 O  O     . THR C 1 374 ? -35.832 2.243   -76.306  1.00 59.65  ? 374 THR C O     1 
ATOM   11064 C  CB    . THR C 1 374 ? -38.207 3.729   -74.856  1.00 62.29  ? 374 THR C CB    1 
ATOM   11065 O  OG1   . THR C 1 374 ? -37.373 4.839   -74.571  1.00 71.76  ? 374 THR C OG1   1 
ATOM   11066 C  CG2   . THR C 1 374 ? -39.488 3.867   -74.063  1.00 71.55  ? 374 THR C CG2   1 
ATOM   11067 N  N     . GLU C 1 375 ? -34.989 2.353   -74.233  1.00 54.16  ? 375 GLU C N     1 
ATOM   11068 C  CA    . GLU C 1 375 ? -33.619 2.217   -74.715  1.00 52.07  ? 375 GLU C CA    1 
ATOM   11069 C  C     . GLU C 1 375 ? -33.381 0.823   -75.312  1.00 52.25  ? 375 GLU C C     1 
ATOM   11070 O  O     . GLU C 1 375 ? -32.558 0.684   -76.202  1.00 51.58  ? 375 GLU C O     1 
ATOM   11071 C  CB    . GLU C 1 375 ? -32.624 2.451   -73.579  1.00 58.08  ? 375 GLU C CB    1 
ATOM   11072 C  CG    . GLU C 1 375 ? -31.221 2.799   -74.055  1.00 56.17  ? 375 GLU C CG    1 
ATOM   11073 C  CD    . GLU C 1 375 ? -31.054 4.195   -74.637  1.00 59.03  ? 375 GLU C CD    1 
ATOM   11074 O  OE1   . GLU C 1 375 ? -31.938 5.076   -74.408  1.00 59.42  ? 375 GLU C OE1   1 
ATOM   11075 O  OE2   . GLU C 1 375 ? -30.043 4.396   -75.351  1.00 56.43  ? 375 GLU C OE2   1 
ATOM   11076 N  N     . PHE C 1 376 ? -34.069 -0.212  -74.802  1.00 51.54  ? 376 PHE C N     1 
ATOM   11077 C  CA    . PHE C 1 376 ? -33.949 -1.578  -75.293  1.00 56.06  ? 376 PHE C CA    1 
ATOM   11078 C  C     . PHE C 1 376 ? -34.347 -1.716  -76.770  1.00 54.52  ? 376 PHE C C     1 
ATOM   11079 O  O     . PHE C 1 376 ? -34.105 -2.765  -77.353  1.00 55.85  ? 376 PHE C O     1 
ATOM   11080 C  CB    . PHE C 1 376 ? -34.838 -2.550  -74.500  1.00 56.51  ? 376 PHE C CB    1 
ATOM   11081 C  CG    . PHE C 1 376 ? -34.309 -3.038  -73.174  1.00 59.41  ? 376 PHE C CG    1 
ATOM   11082 C  CD1   . PHE C 1 376 ? -34.410 -2.252  -72.032  1.00 65.27  ? 376 PHE C CD1   1 
ATOM   11083 C  CD2   . PHE C 1 376 ? -33.755 -4.309  -73.050  1.00 61.81  ? 376 PHE C CD2   1 
ATOM   11084 C  CE1   . PHE C 1 376 ? -33.938 -2.711  -70.809  1.00 65.26  ? 376 PHE C CE1   1 
ATOM   11085 C  CE2   . PHE C 1 376 ? -33.285 -4.771  -71.825  1.00 63.41  ? 376 PHE C CE2   1 
ATOM   11086 C  CZ    . PHE C 1 376 ? -33.372 -3.968  -70.707  1.00 67.31  ? 376 PHE C CZ    1 
ATOM   11087 N  N     . ASN C 1 377 ? -35.010 -0.704  -77.351  1.00 46.71  ? 377 ASN C N     1 
ATOM   11088 C  CA    . ASN C 1 377 ? -35.256 -0.615  -78.788  1.00 52.90  ? 377 ASN C CA    1 
ATOM   11089 C  C     . ASN C 1 377 ? -33.984 -0.771  -79.635  1.00 58.11  ? 377 ASN C C     1 
ATOM   11090 O  O     . ASN C 1 377 ? -34.029 -1.373  -80.705  1.00 52.11  ? 377 ASN C O     1 
ATOM   11091 C  CB    . ASN C 1 377 ? -35.907 0.716   -79.161  1.00 52.32  ? 377 ASN C CB    1 
ATOM   11092 C  CG    . ASN C 1 377 ? -37.333 0.823   -78.656  1.00 56.32  ? 377 ASN C CG    1 
ATOM   11093 O  OD1   . ASN C 1 377 ? -37.864 -0.106  -78.051  1.00 61.76  ? 377 ASN C OD1   1 
ATOM   11094 N  ND2   . ASN C 1 377 ? -37.963 1.956   -78.895  1.00 56.67  ? 377 ASN C ND2   1 
ATOM   11095 N  N     . PHE C 1 378 ? -32.835 -0.246  -79.191  1.00 52.76  ? 378 PHE C N     1 
ATOM   11096 C  CA    . PHE C 1 378 ? -31.657 -0.381  -80.029  1.00 52.74  ? 378 PHE C CA    1 
ATOM   11097 C  C     . PHE C 1 378 ? -31.402 -1.856  -80.345  1.00 48.94  ? 378 PHE C C     1 
ATOM   11098 O  O     . PHE C 1 378 ? -30.723 -2.151  -81.317  1.00 58.15  ? 378 PHE C O     1 
ATOM   11099 C  CB    . PHE C 1 378 ? -30.430 0.329   -79.443  1.00 58.73  ? 378 PHE C CB    1 
ATOM   11100 C  CG    . PHE C 1 378 ? -29.843 -0.206  -78.157  1.00 53.51  ? 378 PHE C CG    1 
ATOM   11101 C  CD1   . PHE C 1 378 ? -29.297 -1.476  -78.077  1.00 56.69  ? 378 PHE C CD1   1 
ATOM   11102 C  CD2   . PHE C 1 378 ? -29.759 0.610   -77.040  1.00 51.67  ? 378 PHE C CD2   1 
ATOM   11103 C  CE1   . PHE C 1 378 ? -28.716 -1.926  -76.898  1.00 59.48  ? 378 PHE C CE1   1 
ATOM   11104 C  CE2   . PHE C 1 378 ? -29.200 0.153   -75.860  1.00 49.56  ? 378 PHE C CE2   1 
ATOM   11105 C  CZ    . PHE C 1 378 ? -28.674 -1.111  -75.792  1.00 53.13  ? 378 PHE C CZ    1 
ATOM   11106 N  N     . LEU C 1 379 ? -31.969 -2.778  -79.555  1.00 49.74  ? 379 LEU C N     1 
ATOM   11107 C  CA    . LEU C 1 379 ? -31.733 -4.201  -79.742  1.00 51.15  ? 379 LEU C CA    1 
ATOM   11108 C  C     . LEU C 1 379 ? -32.341 -4.715  -81.049  1.00 57.03  ? 379 LEU C C     1 
ATOM   11109 O  O     . LEU C 1 379 ? -32.034 -5.844  -81.445  1.00 58.40  ? 379 LEU C O     1 
ATOM   11110 C  CB    . LEU C 1 379 ? -32.335 -4.973  -78.566  1.00 52.47  ? 379 LEU C CB    1 
ATOM   11111 C  CG    . LEU C 1 379 ? -31.561 -4.955  -77.254  1.00 54.95  ? 379 LEU C CG    1 
ATOM   11112 C  CD1   . LEU C 1 379 ? -32.285 -5.808  -76.226  1.00 55.24  ? 379 LEU C CD1   1 
ATOM   11113 C  CD2   . LEU C 1 379 ? -30.139 -5.476  -77.436  1.00 61.35  ? 379 LEU C CD2   1 
ATOM   11114 N  N     . ASN C 1 380 ? -33.223 -3.905  -81.664  1.00 57.03  ? 380 ASN C N     1 
ATOM   11115 C  CA    . ASN C 1 380 ? -33.910 -4.235  -82.902  1.00 57.40  ? 380 ASN C CA    1 
ATOM   11116 C  C     . ASN C 1 380 ? -33.203 -3.668  -84.126  1.00 64.96  ? 380 ASN C C     1 
ATOM   11117 O  O     . ASN C 1 380 ? -33.735 -3.779  -85.234  1.00 63.59  ? 380 ASN C O     1 
ATOM   11118 C  CB    . ASN C 1 380 ? -35.304 -3.617  -82.965  1.00 57.64  ? 380 ASN C CB    1 
ATOM   11119 C  CG    . ASN C 1 380 ? -36.202 -4.084  -81.851  1.00 60.84  ? 380 ASN C CG    1 
ATOM   11120 O  OD1   . ASN C 1 380 ? -36.164 -5.255  -81.479  1.00 60.59  ? 380 ASN C OD1   1 
ATOM   11121 N  ND2   . ASN C 1 380 ? -36.991 -3.171  -81.306  1.00 60.65  ? 380 ASN C ND2   1 
ATOM   11122 N  N     . TRP C 1 381 ? -32.036 -3.031  -83.940  1.00 57.21  ? 381 TRP C N     1 
ATOM   11123 C  CA    . TRP C 1 381 ? -31.357 -2.401  -85.062  1.00 55.15  ? 381 TRP C CA    1 
ATOM   11124 C  C     . TRP C 1 381 ? -31.239 -3.376  -86.236  1.00 53.01  ? 381 TRP C C     1 
ATOM   11125 O  O     . TRP C 1 381 ? -31.471 -2.989  -87.372  1.00 56.75  ? 381 TRP C O     1 
ATOM   11126 C  CB    . TRP C 1 381 ? -29.977 -1.862  -84.661  1.00 48.95  ? 381 TRP C CB    1 
ATOM   11127 C  CG    . TRP C 1 381 ? -29.242 -1.166  -85.766  1.00 42.40  ? 381 TRP C CG    1 
ATOM   11128 C  CD1   . TRP C 1 381 ? -28.058 -1.537  -86.332  1.00 43.67  ? 381 TRP C CD1   1 
ATOM   11129 C  CD2   . TRP C 1 381 ? -29.660 0.021   -86.459  1.00 46.36  ? 381 TRP C CD2   1 
ATOM   11130 N  NE1   . TRP C 1 381 ? -27.680 -0.640  -87.293  1.00 49.19  ? 381 TRP C NE1   1 
ATOM   11131 C  CE2   . TRP C 1 381 ? -28.649 0.325   -87.399  1.00 48.84  ? 381 TRP C CE2   1 
ATOM   11132 C  CE3   . TRP C 1 381 ? -30.768 0.864   -86.356  1.00 45.64  ? 381 TRP C CE3   1 
ATOM   11133 C  CZ2   . TRP C 1 381 ? -28.740 1.414   -88.259  1.00 41.79  ? 381 TRP C CZ2   1 
ATOM   11134 C  CZ3   . TRP C 1 381 ? -30.843 1.960   -87.188  1.00 47.95  ? 381 TRP C CZ3   1 
ATOM   11135 C  CH2   . TRP C 1 381 ? -29.842 2.228   -88.121  1.00 48.81  ? 381 TRP C CH2   1 
ATOM   11136 N  N     . ASP C 1 382 ? -30.836 -4.621  -85.969  1.00 55.86  ? 382 ASP C N     1 
ATOM   11137 C  CA    . ASP C 1 382 ? -30.512 -5.550  -87.039  1.00 61.72  ? 382 ASP C CA    1 
ATOM   11138 C  C     . ASP C 1 382 ? -31.390 -6.795  -86.928  1.00 57.33  ? 382 ASP C C     1 
ATOM   11139 O  O     . ASP C 1 382 ? -30.937 -7.911  -87.139  1.00 59.60  ? 382 ASP C O     1 
ATOM   11140 C  CB    . ASP C 1 382 ? -29.020 -5.891  -87.034  1.00 66.91  ? 382 ASP C CB    1 
ATOM   11141 C  CG    . ASP C 1 382 ? -28.591 -6.622  -88.295  1.00 76.00  ? 382 ASP C CG    1 
ATOM   11142 O  OD1   . ASP C 1 382 ? -29.297 -6.498  -89.308  1.00 75.92  ? 382 ASP C OD1   1 
ATOM   11143 O  OD2   . ASP C 1 382 ? -27.577 -7.335  -88.243  1.00 86.39  ? 382 ASP C OD2   1 
ATOM   11144 N  N     . GLY C 1 383 ? -32.662 -6.601  -86.588  1.00 63.79  ? 383 GLY C N     1 
ATOM   11145 C  CA    . GLY C 1 383 ? -33.618 -7.694  -86.613  1.00 63.71  ? 383 GLY C CA    1 
ATOM   11146 C  C     . GLY C 1 383 ? -33.932 -8.259  -85.230  1.00 68.83  ? 383 GLY C C     1 
ATOM   11147 O  O     . GLY C 1 383 ? -34.989 -8.856  -85.056  1.00 70.80  ? 383 GLY C O     1 
ATOM   11148 N  N     . GLY C 1 384 ? -33.024 -8.096  -84.257  1.00 63.83  ? 384 GLY C N     1 
ATOM   11149 C  CA    . GLY C 1 384 ? -33.331 -8.452  -82.879  1.00 61.86  ? 384 GLY C CA    1 
ATOM   11150 C  C     . GLY C 1 384 ? -32.247 -9.312  -82.236  1.00 70.87  ? 384 GLY C C     1 
ATOM   11151 O  O     . GLY C 1 384 ? -32.120 -10.493 -82.546  1.00 79.03  ? 384 GLY C O     1 
ATOM   11152 N  N     . GLY C 1 385 ? -31.491 -8.731  -81.298  1.00 67.54  ? 385 GLY C N     1 
ATOM   11153 C  CA    . GLY C 1 385 ? -30.417 -9.474  -80.668  1.00 62.16  ? 385 GLY C CA    1 
ATOM   11154 C  C     . GLY C 1 385 ? -30.298 -9.180  -79.178  1.00 64.79  ? 385 GLY C C     1 
ATOM   11155 O  O     . GLY C 1 385 ? -31.205 -8.631  -78.564  1.00 55.26  ? 385 GLY C O     1 
ATOM   11156 N  N     . GLY C 1 386 ? -29.161 -9.596  -78.619  1.00 60.73  ? 386 GLY C N     1 
ATOM   11157 C  CA    . GLY C 1 386 ? -28.742 -9.195  -77.293  1.00 60.03  ? 386 GLY C CA    1 
ATOM   11158 C  C     . GLY C 1 386 ? -27.733 -8.054  -77.370  1.00 59.38  ? 386 GLY C C     1 
ATOM   11159 O  O     . GLY C 1 386 ? -27.369 -7.605  -78.461  1.00 50.03  ? 386 GLY C O     1 
ATOM   11160 N  N     . HIS C 1 387 ? -27.308 -7.582  -76.193  1.00 60.09  ? 387 HIS C N     1 
ATOM   11161 C  CA    . HIS C 1 387 ? -26.210 -6.629  -76.114  1.00 58.07  ? 387 HIS C CA    1 
ATOM   11162 C  C     . HIS C 1 387 ? -25.213 -7.087  -75.060  1.00 52.94  ? 387 HIS C C     1 
ATOM   11163 O  O     . HIS C 1 387 ? -25.491 -7.899  -74.176  1.00 56.13  ? 387 HIS C O     1 
ATOM   11164 C  CB    . HIS C 1 387 ? -26.657 -5.167  -75.922  1.00 57.45  ? 387 HIS C CB    1 
ATOM   11165 C  CG    . HIS C 1 387 ? -27.297 -4.885  -74.604  1.00 69.24  ? 387 HIS C CG    1 
ATOM   11166 N  ND1   . HIS C 1 387 ? -27.457 -6.005  -73.834  1.00 85.77  ? 387 HIS C ND1   1 
ATOM   11167 C  CD2   . HIS C 1 387 ? -27.815 -3.858  -73.887  1.00 73.50  ? 387 HIS C CD2   1 
ATOM   11168 C  CE1   . HIS C 1 387 ? -28.020 -5.683  -72.690  1.00 95.66  ? 387 HIS C CE1   1 
ATOM   11169 N  NE2   . HIS C 1 387 ? -28.324 -4.374  -72.673  1.00 80.30  ? 387 HIS C NE2   1 
ATOM   11170 N  N     . VAL C 1 388 ? -24.012 -6.565  -75.252  1.00 56.15  ? 388 VAL C N     1 
ATOM   11171 C  CA    . VAL C 1 388 ? -22.979 -6.525  -74.248  1.00 55.96  ? 388 VAL C CA    1 
ATOM   11172 C  C     . VAL C 1 388 ? -22.443 -5.101  -74.286  1.00 53.65  ? 388 VAL C C     1 
ATOM   11173 O  O     . VAL C 1 388 ? -22.480 -4.455  -75.334  1.00 53.14  ? 388 VAL C O     1 
ATOM   11174 C  CB    . VAL C 1 388 ? -21.893 -7.570  -74.549  1.00 58.98  ? 388 VAL C CB    1 
ATOM   11175 C  CG1   . VAL C 1 388 ? -20.974 -7.115  -75.679  1.00 60.48  ? 388 VAL C CG1   1 
ATOM   11176 C  CG2   . VAL C 1 388 ? -21.097 -7.927  -73.304  1.00 63.70  ? 388 VAL C CG2   1 
ATOM   11177 N  N     . GLY C 1 389 ? -21.985 -4.617  -73.127  1.00 56.20  ? 389 GLY C N     1 
ATOM   11178 C  CA    . GLY C 1 389 ? -21.430 -3.281  -73.020  1.00 47.40  ? 389 GLY C CA    1 
ATOM   11179 C  C     . GLY C 1 389 ? -19.924 -3.366  -72.828  1.00 48.75  ? 389 GLY C C     1 
ATOM   11180 O  O     . GLY C 1 389 ? -19.430 -4.105  -71.976  1.00 51.18  ? 389 GLY C O     1 
ATOM   11181 N  N     . PHE C 1 390 ? -19.206 -2.608  -73.652  1.00 54.21  ? 390 PHE C N     1 
ATOM   11182 C  CA    . PHE C 1 390 ? -17.782 -2.442  -73.465  1.00 53.22  ? 390 PHE C CA    1 
ATOM   11183 C  C     . PHE C 1 390 ? -17.558 -1.042  -72.915  1.00 46.11  ? 390 PHE C C     1 
ATOM   11184 O  O     . PHE C 1 390 ? -17.791 -0.067  -73.615  1.00 48.75  ? 390 PHE C O     1 
ATOM   11185 C  CB    . PHE C 1 390 ? -17.045 -2.667  -74.785  1.00 53.58  ? 390 PHE C CB    1 
ATOM   11186 C  CG    . PHE C 1 390 ? -15.574 -2.430  -74.617  1.00 54.51  ? 390 PHE C CG    1 
ATOM   11187 C  CD1   . PHE C 1 390 ? -14.838 -3.240  -73.772  1.00 54.60  ? 390 PHE C CD1   1 
ATOM   11188 C  CD2   . PHE C 1 390 ? -14.965 -1.336  -75.198  1.00 50.07  ? 390 PHE C CD2   1 
ATOM   11189 C  CE1   . PHE C 1 390 ? -13.489 -2.997  -73.577  1.00 58.48  ? 390 PHE C CE1   1 
ATOM   11190 C  CE2   . PHE C 1 390 ? -13.620 -1.090  -74.991  1.00 48.96  ? 390 PHE C CE2   1 
ATOM   11191 C  CZ    . PHE C 1 390 ? -12.891 -1.914  -74.173  1.00 53.80  ? 390 PHE C CZ    1 
ATOM   11192 N  N     . SER C 1 391 ? -17.076 -0.946  -71.670  1.00 50.44  ? 391 SER C N     1 
ATOM   11193 C  CA    . SER C 1 391 ? -17.254 0.282   -70.913  1.00 54.30  ? 391 SER C CA    1 
ATOM   11194 C  C     . SER C 1 391 ? -15.946 0.807   -70.310  1.00 53.65  ? 391 SER C C     1 
ATOM   11195 O  O     . SER C 1 391 ? -15.846 0.953   -69.094  1.00 53.66  ? 391 SER C O     1 
ATOM   11196 C  CB    . SER C 1 391 ? -18.300 0.033   -69.843  1.00 58.96  ? 391 SER C CB    1 
ATOM   11197 O  OG    . SER C 1 391 ? -19.283 -0.883  -70.312  1.00 52.80  ? 391 SER C OG    1 
ATOM   11198 N  N     . PRO C 1 392 ? -14.911 1.144   -71.116  1.00 50.19  ? 392 PRO C N     1 
ATOM   11199 C  CA    . PRO C 1 392 ? -13.690 1.751   -70.582  1.00 51.86  ? 392 PRO C CA    1 
ATOM   11200 C  C     . PRO C 1 392 ? -13.895 3.185   -70.100  1.00 49.86  ? 392 PRO C C     1 
ATOM   11201 O  O     . PRO C 1 392 ? -14.839 3.861   -70.519  1.00 49.23  ? 392 PRO C O     1 
ATOM   11202 C  CB    . PRO C 1 392 ? -12.727 1.741   -71.777  1.00 48.56  ? 392 PRO C CB    1 
ATOM   11203 C  CG    . PRO C 1 392 ? -13.658 1.843   -72.960  1.00 51.12  ? 392 PRO C CG    1 
ATOM   11204 C  CD    . PRO C 1 392 ? -14.850 0.989   -72.579  1.00 49.14  ? 392 PRO C CD    1 
ATOM   11205 N  N     . VAL C 1 393 ? -12.975 3.606   -69.224  1.00 44.42  ? 393 VAL C N     1 
ATOM   11206 C  CA    . VAL C 1 393 ? -12.934 4.935   -68.654  1.00 50.28  ? 393 VAL C CA    1 
ATOM   11207 C  C     . VAL C 1 393 ? -11.894 5.758   -69.401  1.00 57.02  ? 393 VAL C C     1 
ATOM   11208 O  O     . VAL C 1 393 ? -10.737 5.353   -69.474  1.00 51.87  ? 393 VAL C O     1 
ATOM   11209 C  CB    . VAL C 1 393 ? -12.559 4.892   -67.162  1.00 50.72  ? 393 VAL C CB    1 
ATOM   11210 C  CG1   . VAL C 1 393 ? -12.575 6.283   -66.544  1.00 48.90  ? 393 VAL C CG1   1 
ATOM   11211 C  CG2   . VAL C 1 393 ? -13.452 3.928   -66.390  1.00 52.39  ? 393 VAL C CG2   1 
ATOM   11212 N  N     . SER C 1 394 ? -12.290 6.968   -69.804  1.00 52.85  ? 394 SER C N     1 
ATOM   11213 C  CA    . SER C 1 394 ? -11.376 7.876   -70.471  1.00 59.66  ? 394 SER C CA    1 
ATOM   11214 C  C     . SER C 1 394 ? -11.330 9.226   -69.755  1.00 56.33  ? 394 SER C C     1 
ATOM   11215 O  O     . SER C 1 394 ? -12.354 9.665   -69.237  1.00 55.21  ? 394 SER C O     1 
ATOM   11216 C  CB    . SER C 1 394 ? -11.821 8.021   -71.891  1.00 51.27  ? 394 SER C CB    1 
ATOM   11217 O  OG    . SER C 1 394 ? -11.200 9.115   -72.506  1.00 54.33  ? 394 SER C OG    1 
ATOM   11218 N  N     . PRO C 1 395 ? -10.176 9.943   -69.771  1.00 48.94  ? 395 PRO C N     1 
ATOM   11219 C  CA    . PRO C 1 395 ? -10.146 11.376  -69.485  1.00 48.70  ? 395 PRO C CA    1 
ATOM   11220 C  C     . PRO C 1 395 ? -11.119 12.155  -70.363  1.00 52.24  ? 395 PRO C C     1 
ATOM   11221 O  O     . PRO C 1 395 ? -11.486 11.667  -71.429  1.00 51.97  ? 395 PRO C O     1 
ATOM   11222 C  CB    . PRO C 1 395 ? -8.733  11.795  -69.860  1.00 43.95  ? 395 PRO C CB    1 
ATOM   11223 C  CG    . PRO C 1 395 ? -7.929  10.527  -69.704  1.00 46.02  ? 395 PRO C CG    1 
ATOM   11224 C  CD    . PRO C 1 395 ? -8.857  9.430   -70.154  1.00 44.98  ? 395 PRO C CD    1 
ATOM   11225 N  N     . ILE C 1 396 ? -11.542 13.346  -69.910  1.00 49.59  ? 396 ILE C N     1 
ATOM   11226 C  CA    . ILE C 1 396 ? -12.336 14.239  -70.745  1.00 51.77  ? 396 ILE C CA    1 
ATOM   11227 C  C     . ILE C 1 396 ? -11.345 15.063  -71.565  1.00 52.11  ? 396 ILE C C     1 
ATOM   11228 O  O     . ILE C 1 396 ? -11.109 16.238  -71.301  1.00 44.74  ? 396 ILE C O     1 
ATOM   11229 C  CB    . ILE C 1 396 ? -13.338 15.102  -69.945  1.00 51.32  ? 396 ILE C CB    1 
ATOM   11230 C  CG1   . ILE C 1 396 ? -14.102 14.308  -68.889  1.00 51.33  ? 396 ILE C CG1   1 
ATOM   11231 C  CG2   . ILE C 1 396 ? -14.319 15.802  -70.874  1.00 48.60  ? 396 ILE C CG2   1 
ATOM   11232 C  CD1   . ILE C 1 396 ? -14.995 15.171  -68.013  1.00 55.68  ? 396 ILE C CD1   1 
ATOM   11233 N  N     . THR C 1 397 ? -10.763 14.384  -72.561  1.00 48.53  ? 397 THR C N     1 
ATOM   11234 C  CA    . THR C 1 397 ? -9.845  14.959  -73.522  1.00 51.06  ? 397 THR C CA    1 
ATOM   11235 C  C     . THR C 1 397 ? -10.296 14.597  -74.938  1.00 48.17  ? 397 THR C C     1 
ATOM   11236 O  O     . THR C 1 397 ? -10.725 13.472  -75.195  1.00 45.74  ? 397 THR C O     1 
ATOM   11237 C  CB    . THR C 1 397 ? -8.441  14.427  -73.226  1.00 54.69  ? 397 THR C CB    1 
ATOM   11238 O  OG1   . THR C 1 397 ? -8.151  14.836  -71.887  1.00 57.17  ? 397 THR C OG1   1 
ATOM   11239 C  CG2   . THR C 1 397 ? -7.402  14.926  -74.190  1.00 54.44  ? 397 THR C CG2   1 
ATOM   11240 N  N     . GLY C 1 398 ? -10.157 15.554  -75.858  1.00 43.95  ? 398 GLY C N     1 
ATOM   11241 C  CA    . GLY C 1 398 ? -10.354 15.305  -77.274  1.00 45.55  ? 398 GLY C CA    1 
ATOM   11242 C  C     . GLY C 1 398 ? -9.550  14.111  -77.767  1.00 44.77  ? 398 GLY C C     1 
ATOM   11243 O  O     . GLY C 1 398 ? -10.094 13.222  -78.410  1.00 46.88  ? 398 GLY C O     1 
ATOM   11244 N  N     . LYS C 1 399 ? -8.253  14.135  -77.461  1.00 46.45  ? 399 LYS C N     1 
ATOM   11245 C  CA    . LYS C 1 399 ? -7.308  13.106  -77.861  1.00 51.51  ? 399 LYS C CA    1 
ATOM   11246 C  C     . LYS C 1 399 ? -7.771  11.708  -77.441  1.00 45.34  ? 399 LYS C C     1 
ATOM   11247 O  O     . LYS C 1 399 ? -7.741  10.790  -78.255  1.00 44.38  ? 399 LYS C O     1 
ATOM   11248 C  CB    . LYS C 1 399 ? -5.926  13.425  -77.277  1.00 58.04  ? 399 LYS C CB    1 
ATOM   11249 C  CG    . LYS C 1 399 ? -4.756  12.703  -77.937  1.00 76.62  ? 399 LYS C CG    1 
ATOM   11250 C  CD    . LYS C 1 399 ? -3.410  12.870  -77.219  1.00 81.94  ? 399 LYS C CD    1 
ATOM   11251 C  CE    . LYS C 1 399 ? -2.314  11.982  -77.775  1.00 85.09  ? 399 LYS C CE    1 
ATOM   11252 N  NZ    . LYS C 1 399 ? -2.700  10.549  -77.736  1.00 91.84  ? 399 LYS C NZ    1 
ATOM   11253 N  N     . ASP C 1 400 ? -8.171  11.515  -76.172  1.00 41.12  ? 400 ASP C N     1 
ATOM   11254 C  CA    . ASP C 1 400 ? -8.536  10.185  -75.684  1.00 40.36  ? 400 ASP C CA    1 
ATOM   11255 C  C     . ASP C 1 400 ? -9.875  9.715   -76.273  1.00 39.62  ? 400 ASP C C     1 
ATOM   11256 O  O     . ASP C 1 400 ? -10.056 8.527   -76.575  1.00 39.56  ? 400 ASP C O     1 
ATOM   11257 C  CB    . ASP C 1 400 ? -8.604  10.146  -74.155  1.00 39.95  ? 400 ASP C CB    1 
ATOM   11258 C  CG    . ASP C 1 400 ? -7.251  10.399  -73.511  1.00 38.81  ? 400 ASP C CG    1 
ATOM   11259 O  OD1   . ASP C 1 400 ? -6.455  9.473   -73.504  1.00 42.66  ? 400 ASP C OD1   1 
ATOM   11260 O  OD2   . ASP C 1 400 ? -7.027  11.524  -73.043  1.00 40.33  ? 400 ASP C OD2   1 
ATOM   11261 N  N     . ALA C 1 401 ? -10.818 10.647  -76.404  1.00 43.75  ? 401 ALA C N     1 
ATOM   11262 C  CA    . ALA C 1 401 ? -12.150 10.352  -76.928  1.00 47.72  ? 401 ALA C CA    1 
ATOM   11263 C  C     . ALA C 1 401 ? -12.051 9.866   -78.371  1.00 45.99  ? 401 ALA C C     1 
ATOM   11264 O  O     . ALA C 1 401 ? -12.437 8.750   -78.692  1.00 49.01  ? 401 ALA C O     1 
ATOM   11265 C  CB    . ALA C 1 401 ? -13.020 11.583  -76.840  1.00 45.80  ? 401 ALA C CB    1 
ATOM   11266 N  N     . ILE C 1 402 ? -11.490 10.703  -79.240  1.00 52.15  ? 402 ILE C N     1 
ATOM   11267 C  CA    . ILE C 1 402 ? -11.364 10.352  -80.643  1.00 48.06  ? 402 ILE C CA    1 
ATOM   11268 C  C     . ILE C 1 402 ? -10.519 9.089   -80.787  1.00 51.50  ? 402 ILE C C     1 
ATOM   11269 O  O     . ILE C 1 402 ? -10.774 8.308   -81.690  1.00 49.99  ? 402 ILE C O     1 
ATOM   11270 C  CB    . ILE C 1 402 ? -10.813 11.525  -81.474  1.00 48.75  ? 402 ILE C CB    1 
ATOM   11271 C  CG1   . ILE C 1 402 ? -11.174 11.368  -82.954  1.00 49.54  ? 402 ILE C CG1   1 
ATOM   11272 C  CG2   . ILE C 1 402 ? -9.312  11.694  -81.243  1.00 49.95  ? 402 ILE C CG2   1 
ATOM   11273 C  CD1   . ILE C 1 402 ? -11.115 12.659  -83.742  1.00 52.59  ? 402 ILE C CD1   1 
ATOM   11274 N  N     . LYS C 1 403 ? -9.543  8.865   -79.887  1.00 50.59  ? 403 LYS C N     1 
ATOM   11275 C  CA    . LYS C 1 403 ? -8.717  7.676   -79.985  1.00 45.18  ? 403 LYS C CA    1 
ATOM   11276 C  C     . LYS C 1 403 ? -9.563  6.421   -79.740  1.00 45.40  ? 403 LYS C C     1 
ATOM   11277 O  O     . LYS C 1 403 ? -9.472  5.445   -80.484  1.00 44.76  ? 403 LYS C O     1 
ATOM   11278 C  CB    . LYS C 1 403 ? -7.538  7.703   -79.007  1.00 49.59  ? 403 LYS C CB    1 
ATOM   11279 C  CG    . LYS C 1 403 ? -6.562  6.554   -79.226  1.00 50.09  ? 403 LYS C CG    1 
ATOM   11280 C  CD    . LYS C 1 403 ? -5.790  6.081   -78.027  1.00 52.46  ? 403 LYS C CD    1 
ATOM   11281 C  CE    . LYS C 1 403 ? -4.413  6.689   -77.898  1.00 53.84  ? 403 LYS C CE    1 
ATOM   11282 N  NZ    . LYS C 1 403 ? -3.467  5.733   -77.257  1.00 51.07  ? 403 LYS C NZ    1 
ATOM   11283 N  N     . GLN C 1 404 ? -10.328 6.425   -78.643  1.00 45.87  ? 404 GLN C N     1 
ATOM   11284 C  CA    . GLN C 1 404 ? -11.117 5.268   -78.259  1.00 49.80  ? 404 GLN C CA    1 
ATOM   11285 C  C     . GLN C 1 404 ? -12.223 5.048   -79.285  1.00 49.64  ? 404 GLN C C     1 
ATOM   11286 O  O     . GLN C 1 404 ? -12.537 3.914   -79.614  1.00 52.01  ? 404 GLN C O     1 
ATOM   11287 C  CB    . GLN C 1 404 ? -11.764 5.447   -76.887  1.00 49.51  ? 404 GLN C CB    1 
ATOM   11288 C  CG    . GLN C 1 404 ? -10.773 5.546   -75.748  1.00 50.99  ? 404 GLN C CG    1 
ATOM   11289 C  CD    . GLN C 1 404 ? -11.465 5.296   -74.438  1.00 52.92  ? 404 GLN C CD    1 
ATOM   11290 O  OE1   . GLN C 1 404 ? -12.671 5.068   -74.387  1.00 59.91  ? 404 GLN C OE1   1 
ATOM   11291 N  NE2   . GLN C 1 404 ? -10.696 5.291   -73.362  1.00 61.41  ? 404 GLN C NE2   1 
ATOM   11292 N  N     . TYR C 1 405 ? -12.822 6.136   -79.774  1.00 43.79  ? 405 TYR C N     1 
ATOM   11293 C  CA    . TYR C 1 405 ? -13.780 6.017   -80.861  1.00 49.32  ? 405 TYR C CA    1 
ATOM   11294 C  C     . TYR C 1 405 ? -13.165 5.225   -82.016  1.00 52.66  ? 405 TYR C C     1 
ATOM   11295 O  O     . TYR C 1 405 ? -13.762 4.257   -82.488  1.00 51.98  ? 405 TYR C O     1 
ATOM   11296 C  CB    . TYR C 1 405 ? -14.269 7.385   -81.342  1.00 52.15  ? 405 TYR C CB    1 
ATOM   11297 C  CG    . TYR C 1 405 ? -15.029 7.330   -82.645  1.00 52.63  ? 405 TYR C CG    1 
ATOM   11298 C  CD1   . TYR C 1 405 ? -16.180 6.564   -82.781  1.00 57.22  ? 405 TYR C CD1   1 
ATOM   11299 C  CD2   . TYR C 1 405 ? -14.567 8.013   -83.755  1.00 53.39  ? 405 TYR C CD2   1 
ATOM   11300 C  CE1   . TYR C 1 405 ? -16.858 6.489   -83.990  1.00 56.83  ? 405 TYR C CE1   1 
ATOM   11301 C  CE2   . TYR C 1 405 ? -15.241 7.966   -84.962  1.00 56.07  ? 405 TYR C CE2   1 
ATOM   11302 C  CZ    . TYR C 1 405 ? -16.382 7.201   -85.077  1.00 53.97  ? 405 TYR C CZ    1 
ATOM   11303 O  OH    . TYR C 1 405 ? -16.995 7.195   -86.282  1.00 64.51  ? 405 TYR C OH    1 
ATOM   11304 N  N     . ASN C 1 406 ? -11.954 5.613   -82.440  1.00 53.21  ? 406 ASN C N     1 
ATOM   11305 C  CA    . ASN C 1 406 ? -11.350 5.015   -83.620  1.00 55.00  ? 406 ASN C CA    1 
ATOM   11306 C  C     . ASN C 1 406 ? -11.042 3.546   -83.377  1.00 50.67  ? 406 ASN C C     1 
ATOM   11307 O  O     . ASN C 1 406 ? -11.382 2.692   -84.182  1.00 50.83  ? 406 ASN C O     1 
ATOM   11308 C  CB    . ASN C 1 406 ? -10.109 5.769   -84.087  1.00 56.50  ? 406 ASN C CB    1 
ATOM   11309 C  CG    . ASN C 1 406 ? -10.493 6.955   -84.934  1.00 54.05  ? 406 ASN C CG    1 
ATOM   11310 O  OD1   . ASN C 1 406 ? -11.290 6.824   -85.854  1.00 72.56  ? 406 ASN C OD1   1 
ATOM   11311 N  ND2   . ASN C 1 406 ? -9.957  8.116   -84.622  1.00 57.55  ? 406 ASN C ND2   1 
ATOM   11312 N  N     . MET C 1 407 ? -10.392 3.262   -82.264  1.00 47.49  ? 407 MET C N     1 
ATOM   11313 C  CA    . MET C 1 407 ? -10.044 1.901   -81.929  1.00 47.17  ? 407 MET C CA    1 
ATOM   11314 C  C     . MET C 1 407 ? -11.286 1.010   -81.913  1.00 52.80  ? 407 MET C C     1 
ATOM   11315 O  O     . MET C 1 407 ? -11.255 -0.109  -82.430  1.00 54.89  ? 407 MET C O     1 
ATOM   11316 C  CB    . MET C 1 407 ? -9.426  1.875   -80.532  1.00 52.77  ? 407 MET C CB    1 
ATOM   11317 C  CG    . MET C 1 407 ? -8.036  2.439   -80.471  1.00 56.31  ? 407 MET C CG    1 
ATOM   11318 S  SD    . MET C 1 407 ? -7.554  2.589   -78.731  1.00 53.92  ? 407 MET C SD    1 
ATOM   11319 C  CE    . MET C 1 407 ? -7.385  0.853   -78.318  1.00 53.18  ? 407 MET C CE    1 
ATOM   11320 N  N     . VAL C 1 408 ? -12.362 1.492   -81.276  1.00 51.10  ? 408 VAL C N     1 
ATOM   11321 C  CA    . VAL C 1 408 ? -13.486 0.632   -80.947  1.00 54.32  ? 408 VAL C CA    1 
ATOM   11322 C  C     . VAL C 1 408 ? -14.376 0.433   -82.170  1.00 52.63  ? 408 VAL C C     1 
ATOM   11323 O  O     . VAL C 1 408 ? -14.748 -0.703  -82.439  1.00 53.98  ? 408 VAL C O     1 
ATOM   11324 C  CB    . VAL C 1 408 ? -14.296 1.128   -79.734  1.00 53.73  ? 408 VAL C CB    1 
ATOM   11325 C  CG1   . VAL C 1 408 ? -15.574 0.318   -79.571  1.00 56.90  ? 408 VAL C CG1   1 
ATOM   11326 C  CG2   . VAL C 1 408 ? -13.475 1.095   -78.442  1.00 51.46  ? 408 VAL C CG2   1 
ATOM   11327 N  N     . SER C 1 409 ? -14.714 1.513   -82.888  1.00 56.50  ? 409 SER C N     1 
ATOM   11328 C  CA    . SER C 1 409 ? -15.604 1.398   -84.032  1.00 58.64  ? 409 SER C CA    1 
ATOM   11329 C  C     . SER C 1 409 ? -14.914 0.593   -85.124  1.00 60.04  ? 409 SER C C     1 
ATOM   11330 O  O     . SER C 1 409 ? -15.573 -0.228  -85.751  1.00 61.65  ? 409 SER C O     1 
ATOM   11331 C  CB    . SER C 1 409 ? -16.113 2.721   -84.544  1.00 54.55  ? 409 SER C CB    1 
ATOM   11332 O  OG    . SER C 1 409 ? -15.063 3.494   -85.083  1.00 64.60  ? 409 SER C OG    1 
ATOM   11333 N  N     . SER C 1 410 ? -13.598 0.797   -85.310  1.00 55.69  ? 410 SER C N     1 
ATOM   11334 C  CA    . SER C 1 410 ? -12.830 0.048   -86.298  1.00 55.39  ? 410 SER C CA    1 
ATOM   11335 C  C     . SER C 1 410 ? -13.060 -1.444  -86.111  1.00 50.04  ? 410 SER C C     1 
ATOM   11336 O  O     . SER C 1 410 ? -13.396 -2.161  -87.043  1.00 52.84  ? 410 SER C O     1 
ATOM   11337 C  CB    . SER C 1 410 ? -11.352 0.310   -86.193  1.00 57.30  ? 410 SER C CB    1 
ATOM   11338 O  OG    . SER C 1 410 ? -11.012 1.482   -86.886  1.00 74.19  ? 410 SER C OG    1 
ATOM   11339 N  N     . ARG C 1 411 ? -12.814 -1.884  -84.884  1.00 50.15  ? 411 ARG C N     1 
ATOM   11340 C  CA    . ARG C 1 411 ? -12.850 -3.289  -84.542  1.00 53.85  ? 411 ARG C CA    1 
ATOM   11341 C  C     . ARG C 1 411 ? -14.274 -3.825  -84.624  1.00 55.76  ? 411 ARG C C     1 
ATOM   11342 O  O     . ARG C 1 411 ? -14.487 -4.944  -85.091  1.00 57.07  ? 411 ARG C O     1 
ATOM   11343 C  CB    . ARG C 1 411 ? -12.278 -3.485  -83.137  1.00 52.12  ? 411 ARG C CB    1 
ATOM   11344 C  CG    . ARG C 1 411 ? -10.771 -3.323  -83.087  1.00 52.61  ? 411 ARG C CG    1 
ATOM   11345 C  CD    . ARG C 1 411 ? -10.122 -4.405  -83.914  1.00 49.71  ? 411 ARG C CD    1 
ATOM   11346 N  NE    . ARG C 1 411 ? -8.699  -4.444  -83.678  1.00 53.12  ? 411 ARG C NE    1 
ATOM   11347 C  CZ    . ARG C 1 411 ? -7.798  -4.865  -84.556  1.00 51.11  ? 411 ARG C CZ    1 
ATOM   11348 N  NH1   . ARG C 1 411 ? -8.182  -5.320  -85.737  1.00 48.35  ? 411 ARG C NH1   1 
ATOM   11349 N  NH2   . ARG C 1 411 ? -6.513  -4.784  -84.263  1.00 50.89  ? 411 ARG C NH2   1 
ATOM   11350 N  N     . VAL C 1 412 ? -15.234 -3.036  -84.138  1.00 54.43  ? 412 VAL C N     1 
ATOM   11351 C  CA    . VAL C 1 412 ? -16.612 -3.489  -84.083  1.00 50.57  ? 412 VAL C CA    1 
ATOM   11352 C  C     . VAL C 1 412 ? -17.114 -3.698  -85.520  1.00 51.65  ? 412 VAL C C     1 
ATOM   11353 O  O     . VAL C 1 412 ? -17.650 -4.753  -85.846  1.00 49.94  ? 412 VAL C O     1 
ATOM   11354 C  CB    . VAL C 1 412 ? -17.465 -2.519  -83.242  1.00 55.86  ? 412 VAL C CB    1 
ATOM   11355 C  CG1   . VAL C 1 412 ? -18.949 -2.858  -83.276  1.00 62.01  ? 412 VAL C CG1   1 
ATOM   11356 C  CG2   . VAL C 1 412 ? -17.001 -2.492  -81.793  1.00 59.06  ? 412 VAL C CG2   1 
ATOM   11357 N  N     . ARG C 1 413 ? -16.855 -2.714  -86.386  1.00 51.36  ? 413 ARG C N     1 
ATOM   11358 C  CA    . ARG C 1 413 ? -17.274 -2.739  -87.773  1.00 48.11  ? 413 ARG C CA    1 
ATOM   11359 C  C     . ARG C 1 413 ? -16.519 -3.813  -88.556  1.00 55.74  ? 413 ARG C C     1 
ATOM   11360 O  O     . ARG C 1 413 ? -17.111 -4.512  -89.365  1.00 62.98  ? 413 ARG C O     1 
ATOM   11361 C  CB    . ARG C 1 413 ? -17.106 -1.342  -88.359  1.00 48.51  ? 413 ARG C CB    1 
ATOM   11362 C  CG    . ARG C 1 413 ? -18.114 -0.344  -87.808  1.00 50.08  ? 413 ARG C CG    1 
ATOM   11363 C  CD    . ARG C 1 413 ? -17.824 1.070   -88.267  1.00 53.07  ? 413 ARG C CD    1 
ATOM   11364 N  NE    . ARG C 1 413 ? -17.630 1.110   -89.712  1.00 59.47  ? 413 ARG C NE    1 
ATOM   11365 C  CZ    . ARG C 1 413 ? -18.602 1.306   -90.596  1.00 58.91  ? 413 ARG C CZ    1 
ATOM   11366 N  NH1   . ARG C 1 413 ? -19.858 1.455   -90.204  1.00 58.21  ? 413 ARG C NH1   1 
ATOM   11367 N  NH2   . ARG C 1 413 ? -18.318 1.308   -91.882  1.00 57.94  ? 413 ARG C NH2   1 
ATOM   11368 N  N     . GLU C 1 414 ? -15.230 -3.988  -88.271  1.00 56.95  ? 414 GLU C N     1 
ATOM   11369 C  CA    . GLU C 1 414 ? -14.471 -5.078  -88.850  1.00 56.81  ? 414 GLU C CA    1 
ATOM   11370 C  C     . GLU C 1 414 ? -15.130 -6.413  -88.507  1.00 56.59  ? 414 GLU C C     1 
ATOM   11371 O  O     . GLU C 1 414 ? -15.135 -7.322  -89.326  1.00 59.99  ? 414 GLU C O     1 
ATOM   11372 C  CB    . GLU C 1 414 ? -13.010 -4.967  -88.404  1.00 59.61  ? 414 GLU C CB    1 
ATOM   11373 C  CG    . GLU C 1 414 ? -12.223 -6.259  -88.442  1.00 58.75  ? 414 GLU C CG    1 
ATOM   11374 C  CD    . GLU C 1 414 ? -10.912 -6.196  -87.669  1.00 67.58  ? 414 GLU C CD    1 
ATOM   11375 O  OE1   . GLU C 1 414 ? -10.508 -5.085  -87.243  1.00 64.39  ? 414 GLU C OE1   1 
ATOM   11376 O  OE2   . GLU C 1 414 ? -10.304 -7.261  -87.471  1.00 62.67  ? 414 GLU C OE2   1 
ATOM   11377 N  N     . TYR C 1 415 ? -15.698 -6.563  -87.308  1.00 61.79  ? 415 TYR C N     1 
ATOM   11378 C  CA    . TYR C 1 415 ? -16.340 -7.828  -86.963  1.00 56.50  ? 415 TYR C CA    1 
ATOM   11379 C  C     . TYR C 1 415 ? -17.798 -7.829  -87.417  1.00 58.00  ? 415 TYR C C     1 
ATOM   11380 O  O     . TYR C 1 415 ? -18.513 -8.791  -87.151  1.00 55.86  ? 415 TYR C O     1 
ATOM   11381 C  CB    . TYR C 1 415 ? -16.175 -8.161  -85.478  1.00 51.86  ? 415 TYR C CB    1 
ATOM   11382 C  CG    . TYR C 1 415 ? -14.851 -8.810  -85.182  1.00 47.45  ? 415 TYR C CG    1 
ATOM   11383 C  CD1   . TYR C 1 415 ? -13.682 -8.081  -85.289  1.00 46.19  ? 415 TYR C CD1   1 
ATOM   11384 C  CD2   . TYR C 1 415 ? -14.749 -10.161 -84.898  1.00 52.59  ? 415 TYR C CD2   1 
ATOM   11385 C  CE1   . TYR C 1 415 ? -12.445 -8.653  -85.064  1.00 48.71  ? 415 TYR C CE1   1 
ATOM   11386 C  CE2   . TYR C 1 415 ? -13.513 -10.756 -84.682  1.00 50.80  ? 415 TYR C CE2   1 
ATOM   11387 C  CZ    . TYR C 1 415 ? -12.362 -9.996  -84.765  1.00 48.89  ? 415 TYR C CZ    1 
ATOM   11388 O  OH    . TYR C 1 415 ? -11.120 -10.517 -84.563  1.00 52.37  ? 415 TYR C OH    1 
ATOM   11389 N  N     . GLY C 1 416 ? -18.213 -6.757  -88.112  1.00 61.72  ? 416 GLY C N     1 
ATOM   11390 C  CA    . GLY C 1 416 ? -19.488 -6.724  -88.809  1.00 60.86  ? 416 GLY C CA    1 
ATOM   11391 C  C     . GLY C 1 416 ? -20.648 -6.249  -87.931  1.00 65.13  ? 416 GLY C C     1 
ATOM   11392 O  O     . GLY C 1 416 ? -21.806 -6.481  -88.264  1.00 66.16  ? 416 GLY C O     1 
ATOM   11393 N  N     . PHE C 1 417 ? -20.353 -5.575  -86.816  1.00 54.56  ? 417 PHE C N     1 
ATOM   11394 C  CA    . PHE C 1 417 ? -21.400 -4.915  -86.061  1.00 52.48  ? 417 PHE C CA    1 
ATOM   11395 C  C     . PHE C 1 417 ? -21.308 -3.414  -86.318  1.00 54.68  ? 417 PHE C C     1 
ATOM   11396 O  O     . PHE C 1 417 ? -20.271 -2.895  -86.726  1.00 63.47  ? 417 PHE C O     1 
ATOM   11397 C  CB    . PHE C 1 417 ? -21.305 -5.290  -84.581  1.00 54.68  ? 417 PHE C CB    1 
ATOM   11398 C  CG    . PHE C 1 417 ? -21.224 -6.769  -84.286  1.00 50.62  ? 417 PHE C CG    1 
ATOM   11399 C  CD1   . PHE C 1 417 ? -22.357 -7.560  -84.280  1.00 46.77  ? 417 PHE C CD1   1 
ATOM   11400 C  CD2   . PHE C 1 417 ? -20.007 -7.366  -84.001  1.00 53.08  ? 417 PHE C CD2   1 
ATOM   11401 C  CE1   . PHE C 1 417 ? -22.276 -8.915  -84.006  1.00 41.80  ? 417 PHE C CE1   1 
ATOM   11402 C  CE2   . PHE C 1 417 ? -19.925 -8.717  -83.705  1.00 49.10  ? 417 PHE C CE2   1 
ATOM   11403 C  CZ    . PHE C 1 417 ? -21.060 -9.489  -83.715  1.00 53.19  ? 417 PHE C CZ    1 
ATOM   11404 N  N     . ASP C 1 418 ? -22.426 -2.722  -86.156  1.00 52.14  ? 418 ASP C N     1 
ATOM   11405 C  CA    . ASP C 1 418 ? -22.409 -1.271  -86.218  1.00 54.05  ? 418 ASP C CA    1 
ATOM   11406 C  C     . ASP C 1 418 ? -21.847 -0.741  -84.903  1.00 49.98  ? 418 ASP C C     1 
ATOM   11407 O  O     . ASP C 1 418 ? -22.148 -1.256  -83.826  1.00 45.73  ? 418 ASP C O     1 
ATOM   11408 C  CB    . ASP C 1 418 ? -23.803 -0.683  -86.468  1.00 47.83  ? 418 ASP C CB    1 
ATOM   11409 C  CG    . ASP C 1 418 ? -24.220 -0.623  -87.929  1.00 52.06  ? 418 ASP C CG    1 
ATOM   11410 O  OD1   . ASP C 1 418 ? -23.587 0.142   -88.683  1.00 50.77  ? 418 ASP C OD1   1 
ATOM   11411 O  OD2   . ASP C 1 418 ? -25.215 -1.297  -88.292  1.00 58.36  ? 418 ASP C OD2   1 
ATOM   11412 N  N     . TYR C 1 419 ? -21.044 0.312   -85.008  1.00 61.10  ? 419 TYR C N     1 
ATOM   11413 C  CA    . TYR C 1 419 ? -20.571 1.012   -83.826  1.00 63.67  ? 419 TYR C CA    1 
ATOM   11414 C  C     . TYR C 1 419 ? -21.742 1.727   -83.162  1.00 56.01  ? 419 TYR C C     1 
ATOM   11415 O  O     . TYR C 1 419 ? -22.377 2.572   -83.771  1.00 48.94  ? 419 TYR C O     1 
ATOM   11416 C  CB    . TYR C 1 419 ? -19.498 2.051   -84.157  1.00 60.81  ? 419 TYR C CB    1 
ATOM   11417 C  CG    . TYR C 1 419 ? -19.141 2.908   -82.970  1.00 61.79  ? 419 TYR C CG    1 
ATOM   11418 C  CD1   . TYR C 1 419 ? -18.602 2.329   -81.834  1.00 59.29  ? 419 TYR C CD1   1 
ATOM   11419 C  CD2   . TYR C 1 419 ? -19.391 4.274   -82.950  1.00 64.96  ? 419 TYR C CD2   1 
ATOM   11420 C  CE1   . TYR C 1 419 ? -18.276 3.089   -80.725  1.00 63.76  ? 419 TYR C CE1   1 
ATOM   11421 C  CE2   . TYR C 1 419 ? -19.090 5.048   -81.839  1.00 65.04  ? 419 TYR C CE2   1 
ATOM   11422 C  CZ    . TYR C 1 419 ? -18.522 4.452   -80.724  1.00 63.33  ? 419 TYR C CZ    1 
ATOM   11423 O  OH    . TYR C 1 419 ? -18.184 5.153   -79.594  1.00 57.90  ? 419 TYR C OH    1 
ATOM   11424 N  N     . MET C 1 420 ? -21.984 1.416   -81.890  1.00 59.34  ? 420 MET C N     1 
ATOM   11425 C  CA    . MET C 1 420 ? -22.957 2.153   -81.109  1.00 56.62  ? 420 MET C CA    1 
ATOM   11426 C  C     . MET C 1 420 ? -22.288 2.688   -79.837  1.00 55.68  ? 420 MET C C     1 
ATOM   11427 O  O     . MET C 1 420 ? -21.977 1.922   -78.934  1.00 59.44  ? 420 MET C O     1 
ATOM   11428 C  CB    . MET C 1 420 ? -24.118 1.217   -80.779  1.00 54.17  ? 420 MET C CB    1 
ATOM   11429 C  CG    . MET C 1 420 ? -25.009 0.889   -81.985  1.00 55.94  ? 420 MET C CG    1 
ATOM   11430 S  SD    . MET C 1 420 ? -26.374 -0.185  -81.456  1.00 55.38  ? 420 MET C SD    1 
ATOM   11431 C  CE    . MET C 1 420 ? -27.051 -0.726  -83.027  1.00 57.39  ? 420 MET C CE    1 
ATOM   11432 N  N     . GLY C 1 421 ? -22.116 4.019   -79.763  1.00 56.61  ? 421 GLY C N     1 
ATOM   11433 C  CA    . GLY C 1 421 ? -21.229 4.667   -78.801  1.00 49.36  ? 421 GLY C CA    1 
ATOM   11434 C  C     . GLY C 1 421 ? -21.912 5.727   -77.941  1.00 50.99  ? 421 GLY C C     1 
ATOM   11435 O  O     . GLY C 1 421 ? -22.478 6.667   -78.479  1.00 57.86  ? 421 GLY C O     1 
ATOM   11436 N  N     . LEU C 1 422 ? -21.828 5.553   -76.606  1.00 59.39  ? 422 LEU C N     1 
ATOM   11437 C  CA    . LEU C 1 422 ? -22.225 6.538   -75.599  1.00 62.70  ? 422 LEU C CA    1 
ATOM   11438 C  C     . LEU C 1 422 ? -20.992 7.038   -74.837  1.00 64.15  ? 422 LEU C C     1 
ATOM   11439 O  O     . LEU C 1 422 ? -20.235 6.251   -74.272  1.00 54.09  ? 422 LEU C O     1 
ATOM   11440 C  CB    . LEU C 1 422 ? -23.239 5.893   -74.638  1.00 60.73  ? 422 LEU C CB    1 
ATOM   11441 C  CG    . LEU C 1 422 ? -23.362 6.493   -73.231  1.00 64.62  ? 422 LEU C CG    1 
ATOM   11442 C  CD1   . LEU C 1 422 ? -23.905 7.918   -73.257  1.00 59.41  ? 422 LEU C CD1   1 
ATOM   11443 C  CD2   . LEU C 1 422 ? -24.247 5.618   -72.349  1.00 71.28  ? 422 LEU C CD2   1 
ATOM   11444 N  N     . LEU C 1 423 ? -20.818 8.365   -74.822  1.00 70.13  ? 423 LEU C N     1 
ATOM   11445 C  CA    . LEU C 1 423 ? -19.880 9.044   -73.941  1.00 59.92  ? 423 LEU C CA    1 
ATOM   11446 C  C     . LEU C 1 423 ? -20.656 9.702   -72.804  1.00 60.60  ? 423 LEU C C     1 
ATOM   11447 O  O     . LEU C 1 423 ? -21.275 10.741  -73.012  1.00 53.32  ? 423 LEU C O     1 
ATOM   11448 C  CB    . LEU C 1 423 ? -19.103 10.075  -74.760  1.00 56.80  ? 423 LEU C CB    1 
ATOM   11449 C  CG    . LEU C 1 423 ? -18.197 9.488   -75.837  1.00 58.15  ? 423 LEU C CG    1 
ATOM   11450 C  CD1   . LEU C 1 423 ? -17.274 10.550  -76.413  1.00 57.12  ? 423 LEU C CD1   1 
ATOM   11451 C  CD2   . LEU C 1 423 ? -17.371 8.329   -75.289  1.00 64.90  ? 423 LEU C CD2   1 
ATOM   11452 N  N     . ALA C 1 424 ? -20.660 9.042   -71.631  1.00 50.25  ? 424 ALA C N     1 
ATOM   11453 C  CA    . ALA C 1 424 ? -21.313 9.553   -70.440  1.00 59.62  ? 424 ALA C CA    1 
ATOM   11454 C  C     . ALA C 1 424 ? -20.307 10.391  -69.650  1.00 58.28  ? 424 ALA C C     1 
ATOM   11455 O  O     . ALA C 1 424 ? -19.185 9.949   -69.430  1.00 65.08  ? 424 ALA C O     1 
ATOM   11456 C  CB    . ALA C 1 424 ? -21.857 8.405   -69.623  1.00 62.88  ? 424 ALA C CB    1 
ATOM   11457 N  N     . ILE C 1 425 ? -20.702 11.618  -69.296  1.00 58.82  ? 425 ILE C N     1 
ATOM   11458 C  CA    . ILE C 1 425 ? -19.798 12.584  -68.689  1.00 58.85  ? 425 ILE C CA    1 
ATOM   11459 C  C     . ILE C 1 425 ? -19.941 12.470  -67.184  1.00 45.77  ? 425 ILE C C     1 
ATOM   11460 O  O     . ILE C 1 425 ? -21.008 12.772  -66.675  1.00 46.11  ? 425 ILE C O     1 
ATOM   11461 C  CB    . ILE C 1 425 ? -20.106 14.030  -69.121  1.00 60.10  ? 425 ILE C CB    1 
ATOM   11462 C  CG1   . ILE C 1 425 ? -20.438 14.145  -70.615  1.00 63.67  ? 425 ILE C CG1   1 
ATOM   11463 C  CG2   . ILE C 1 425 ? -18.941 14.931  -68.719  1.00 63.26  ? 425 ILE C CG2   1 
ATOM   11464 C  CD1   . ILE C 1 425 ? -21.037 15.486  -71.014  1.00 59.54  ? 425 ILE C CD1   1 
ATOM   11465 N  N     . GLY C 1 426 ? -18.904 11.971  -66.502  1.00 42.45  ? 426 GLY C N     1 
ATOM   11466 C  CA    . GLY C 1 426 ? -18.830 12.083  -65.048  1.00 43.25  ? 426 GLY C CA    1 
ATOM   11467 C  C     . GLY C 1 426 ? -18.229 13.432  -64.648  1.00 40.85  ? 426 GLY C C     1 
ATOM   11468 O  O     . GLY C 1 426 ? -18.131 14.349  -65.472  1.00 48.80  ? 426 GLY C O     1 
ATOM   11469 N  N     . TRP C 1 427 ? -17.767 13.554  -63.403  1.00 42.18  ? 427 TRP C N     1 
ATOM   11470 C  CA    . TRP C 1 427 ? -17.263 14.847  -62.952  1.00 45.12  ? 427 TRP C CA    1 
ATOM   11471 C  C     . TRP C 1 427 ? -15.921 15.159  -63.615  1.00 40.34  ? 427 TRP C C     1 
ATOM   11472 O  O     . TRP C 1 427 ? -15.690 16.287  -64.038  1.00 44.54  ? 427 TRP C O     1 
ATOM   11473 C  CB    . TRP C 1 427 ? -17.175 14.910  -61.430  1.00 49.06  ? 427 TRP C CB    1 
ATOM   11474 C  CG    . TRP C 1 427 ? -17.175 16.315  -60.899  1.00 51.18  ? 427 TRP C CG    1 
ATOM   11475 C  CD1   . TRP C 1 427 ? -17.057 17.487  -61.596  1.00 48.64  ? 427 TRP C CD1   1 
ATOM   11476 C  CD2   . TRP C 1 427 ? -17.303 16.687  -59.514  1.00 59.24  ? 427 TRP C CD2   1 
ATOM   11477 N  NE1   . TRP C 1 427 ? -17.084 18.558  -60.743  1.00 50.30  ? 427 TRP C NE1   1 
ATOM   11478 C  CE2   . TRP C 1 427 ? -17.244 18.099  -59.458  1.00 57.95  ? 427 TRP C CE2   1 
ATOM   11479 C  CE3   . TRP C 1 427 ? -17.456 15.964  -58.320  1.00 63.60  ? 427 TRP C CE3   1 
ATOM   11480 C  CZ2   . TRP C 1 427 ? -17.352 18.789  -58.249  1.00 60.67  ? 427 TRP C CZ2   1 
ATOM   11481 C  CZ3   . TRP C 1 427 ? -17.549 16.652  -57.127  1.00 61.69  ? 427 TRP C CZ3   1 
ATOM   11482 C  CH2   . TRP C 1 427 ? -17.508 18.046  -57.098  1.00 56.18  ? 427 TRP C CH2   1 
ATOM   11483 N  N     . ARG C 1 428 ? -15.049 14.156  -63.739  1.00 36.66  ? 428 ARG C N     1 
ATOM   11484 C  CA    . ARG C 1 428 ? -13.743 14.382  -64.345  1.00 38.16  ? 428 ARG C CA    1 
ATOM   11485 C  C     . ARG C 1 428 ? -13.356 13.269  -65.314  1.00 38.78  ? 428 ARG C C     1 
ATOM   11486 O  O     . ARG C 1 428 ? -12.226 13.276  -65.777  1.00 42.69  ? 428 ARG C O     1 
ATOM   11487 C  CB    . ARG C 1 428 ? -12.729 14.561  -63.217  1.00 40.37  ? 428 ARG C CB    1 
ATOM   11488 C  CG    . ARG C 1 428 ? -12.735 15.983  -62.680  1.00 42.98  ? 428 ARG C CG    1 
ATOM   11489 C  CD    . ARG C 1 428 ? -12.381 16.057  -61.228  1.00 45.21  ? 428 ARG C CD    1 
ATOM   11490 N  NE    . ARG C 1 428 ? -12.046 17.408  -60.810  1.00 46.46  ? 428 ARG C NE    1 
ATOM   11491 C  CZ    . ARG C 1 428 ? -12.818 18.199  -60.069  1.00 46.64  ? 428 ARG C CZ    1 
ATOM   11492 N  NH1   . ARG C 1 428 ? -14.089 17.886  -59.866  1.00 43.57  ? 428 ARG C NH1   1 
ATOM   11493 N  NH2   . ARG C 1 428 ? -12.321 19.331  -59.583  1.00 40.60  ? 428 ARG C NH2   1 
ATOM   11494 N  N     . ASP C 1 429 ? -14.302 12.379  -65.649  1.00 37.34  ? 429 ASP C N     1 
ATOM   11495 C  CA    . ASP C 1 429 ? -14.075 11.195  -66.478  1.00 43.33  ? 429 ASP C CA    1 
ATOM   11496 C  C     . ASP C 1 429 ? -15.160 11.054  -67.570  1.00 50.62  ? 429 ASP C C     1 
ATOM   11497 O  O     . ASP C 1 429 ? -16.259 11.622  -67.454  1.00 46.04  ? 429 ASP C O     1 
ATOM   11498 C  CB    . ASP C 1 429 ? -14.085 9.950   -65.591  1.00 43.27  ? 429 ASP C CB    1 
ATOM   11499 C  CG    . ASP C 1 429 ? -15.486 9.497   -65.192  1.00 49.99  ? 429 ASP C CG    1 
ATOM   11500 O  OD1   . ASP C 1 429 ? -16.077 10.142  -64.321  1.00 45.47  ? 429 ASP C OD1   1 
ATOM   11501 O  OD2   . ASP C 1 429 ? -16.004 8.547   -65.821  1.00 58.54  ? 429 ASP C OD2   1 
ATOM   11502 N  N     . LEU C 1 430 ? -14.869 10.277  -68.636  1.00 54.23  ? 430 LEU C N     1 
ATOM   11503 C  CA    . LEU C 1 430 ? -15.919 9.761   -69.518  1.00 55.02  ? 430 LEU C CA    1 
ATOM   11504 C  C     . LEU C 1 430 ? -16.029 8.247   -69.370  1.00 56.42  ? 430 LEU C C     1 
ATOM   11505 O  O     . LEU C 1 430 ? -15.037 7.546   -69.512  1.00 55.72  ? 430 LEU C O     1 
ATOM   11506 C  CB    . LEU C 1 430 ? -15.621 10.099  -70.978  1.00 63.40  ? 430 LEU C CB    1 
ATOM   11507 C  CG    . LEU C 1 430 ? -15.851 11.548  -71.389  1.00 61.99  ? 430 LEU C CG    1 
ATOM   11508 C  CD1   . LEU C 1 430 ? -15.289 11.776  -72.771  1.00 55.39  ? 430 LEU C CD1   1 
ATOM   11509 C  CD2   . LEU C 1 430 ? -17.326 11.901  -71.334  1.00 71.50  ? 430 LEU C CD2   1 
ATOM   11510 N  N     . HIS C 1 431 ? -17.241 7.764   -69.066  1.00 57.74  ? 431 HIS C N     1 
ATOM   11511 C  CA    . HIS C 1 431 ? -17.587 6.364   -69.268  1.00 65.38  ? 431 HIS C CA    1 
ATOM   11512 C  C     . HIS C 1 431 ? -17.980 6.161   -70.731  1.00 58.98  ? 431 HIS C C     1 
ATOM   11513 O  O     . HIS C 1 431 ? -19.028 6.644   -71.148  1.00 55.01  ? 431 HIS C O     1 
ATOM   11514 C  CB    . HIS C 1 431 ? -18.745 5.931   -68.354  1.00 61.50  ? 431 HIS C CB    1 
ATOM   11515 C  CG    . HIS C 1 431 ? -18.338 5.825   -66.933  1.00 72.24  ? 431 HIS C CG    1 
ATOM   11516 N  ND1   . HIS C 1 431 ? -19.184 5.413   -65.924  1.00 71.58  ? 431 HIS C ND1   1 
ATOM   11517 C  CD2   . HIS C 1 431 ? -17.147 6.076   -66.361  1.00 71.96  ? 431 HIS C CD2   1 
ATOM   11518 C  CE1   . HIS C 1 431 ? -18.524 5.436   -64.777  1.00 64.01  ? 431 HIS C CE1   1 
ATOM   11519 N  NE2   . HIS C 1 431 ? -17.287 5.831   -65.021  1.00 73.29  ? 431 HIS C NE2   1 
ATOM   11520 N  N     . HIS C 1 432 ? -17.144 5.432   -71.478  1.00 58.36  ? 432 HIS C N     1 
ATOM   11521 C  CA    . HIS C 1 432 ? -17.370 5.145   -72.888  1.00 63.12  ? 432 HIS C CA    1 
ATOM   11522 C  C     . HIS C 1 432 ? -18.073 3.791   -73.020  1.00 62.91  ? 432 HIS C C     1 
ATOM   11523 O  O     . HIS C 1 432 ? -17.415 2.754   -73.079  1.00 51.57  ? 432 HIS C O     1 
ATOM   11524 C  CB    . HIS C 1 432 ? -16.036 5.193   -73.640  1.00 58.98  ? 432 HIS C CB    1 
ATOM   11525 C  CG    . HIS C 1 432 ? -16.129 4.915   -75.090  1.00 60.21  ? 432 HIS C CG    1 
ATOM   11526 N  ND1   . HIS C 1 432 ? -14.999 4.742   -75.862  1.00 53.12  ? 432 HIS C ND1   1 
ATOM   11527 C  CD2   . HIS C 1 432 ? -17.170 4.763   -75.915  1.00 64.28  ? 432 HIS C CD2   1 
ATOM   11528 C  CE1   . HIS C 1 432 ? -15.360 4.482   -77.114  1.00 52.69  ? 432 HIS C CE1   1 
ATOM   11529 N  NE2   . HIS C 1 432 ? -16.663 4.508   -77.180  1.00 58.09  ? 432 HIS C NE2   1 
ATOM   11530 N  N     . VAL C 1 433 ? -19.418 3.801   -73.041  1.00 57.17  ? 433 VAL C N     1 
ATOM   11531 C  CA    . VAL C 1 433 ? -20.158 2.552   -73.128  1.00 67.01  ? 433 VAL C CA    1 
ATOM   11532 C  C     . VAL C 1 433 ? -20.422 2.285   -74.610  1.00 72.14  ? 433 VAL C C     1 
ATOM   11533 O  O     . VAL C 1 433 ? -21.222 2.972   -75.240  1.00 65.62  ? 433 VAL C O     1 
ATOM   11534 C  CB    . VAL C 1 433 ? -21.457 2.544   -72.287  1.00 71.28  ? 433 VAL C CB    1 
ATOM   11535 C  CG1   . VAL C 1 433 ? -22.064 1.150   -72.228  1.00 74.13  ? 433 VAL C CG1   1 
ATOM   11536 C  CG2   . VAL C 1 433 ? -21.258 3.066   -70.868  1.00 74.96  ? 433 VAL C CG2   1 
ATOM   11537 N  N     . THR C 1 434 ? -19.710 1.297   -75.167  1.00 70.59  ? 434 THR C N     1 
ATOM   11538 C  CA    . THR C 1 434 ? -20.002 0.797   -76.499  1.00 60.39  ? 434 THR C CA    1 
ATOM   11539 C  C     . THR C 1 434 ? -21.010 -0.343  -76.408  1.00 55.17  ? 434 THR C C     1 
ATOM   11540 O  O     . THR C 1 434 ? -20.714 -1.379  -75.826  1.00 47.97  ? 434 THR C O     1 
ATOM   11541 C  CB    . THR C 1 434 ? -18.727 0.324   -77.195  1.00 56.61  ? 434 THR C CB    1 
ATOM   11542 O  OG1   . THR C 1 434 ? -17.949 1.508   -77.337  1.00 67.89  ? 434 THR C OG1   1 
ATOM   11543 C  CG2   . THR C 1 434 ? -18.982 -0.319  -78.542  1.00 60.49  ? 434 THR C CG2   1 
ATOM   11544 N  N     . VAL C 1 435 ? -22.189 -0.168  -77.010  1.00 54.65  ? 435 VAL C N     1 
ATOM   11545 C  CA    . VAL C 1 435 ? -23.168 -1.237  -76.965  1.00 57.56  ? 435 VAL C CA    1 
ATOM   11546 C  C     . VAL C 1 435 ? -23.038 -2.036  -78.266  1.00 54.80  ? 435 VAL C C     1 
ATOM   11547 O  O     . VAL C 1 435 ? -23.220 -1.492  -79.351  1.00 51.55  ? 435 VAL C O     1 
ATOM   11548 C  CB    . VAL C 1 435 ? -24.594 -0.718  -76.682  1.00 58.77  ? 435 VAL C CB    1 
ATOM   11549 C  CG1   . VAL C 1 435 ? -24.586 0.641   -75.995  1.00 59.93  ? 435 VAL C CG1   1 
ATOM   11550 C  CG2   . VAL C 1 435 ? -25.471 -0.660  -77.911  1.00 63.27  ? 435 VAL C CG2   1 
ATOM   11551 N  N     . ILE C 1 436 ? -22.664 -3.319  -78.140  1.00 49.22  ? 436 ILE C N     1 
ATOM   11552 C  CA    . ILE C 1 436 ? -22.544 -4.206  -79.283  1.00 48.91  ? 436 ILE C CA    1 
ATOM   11553 C  C     . ILE C 1 436 ? -23.773 -5.109  -79.346  1.00 50.45  ? 436 ILE C C     1 
ATOM   11554 O  O     . ILE C 1 436 ? -23.959 -5.950  -78.467  1.00 51.47  ? 436 ILE C O     1 
ATOM   11555 C  CB    . ILE C 1 436 ? -21.256 -5.042  -79.198  1.00 51.28  ? 436 ILE C CB    1 
ATOM   11556 C  CG1   . ILE C 1 436 ? -20.034 -4.168  -78.906  1.00 54.80  ? 436 ILE C CG1   1 
ATOM   11557 C  CG2   . ILE C 1 436 ? -21.085 -5.846  -80.477  1.00 52.43  ? 436 ILE C CG2   1 
ATOM   11558 C  CD1   . ILE C 1 436 ? -18.800 -4.964  -78.550  1.00 58.16  ? 436 ILE C CD1   1 
ATOM   11559 N  N     . VAL C 1 437 ? -24.587 -4.925  -80.399  1.00 50.00  ? 437 VAL C N     1 
ATOM   11560 C  CA    . VAL C 1 437 ? -25.797 -5.710  -80.603  1.00 54.53  ? 437 VAL C CA    1 
ATOM   11561 C  C     . VAL C 1 437 ? -25.500 -6.877  -81.544  1.00 53.35  ? 437 VAL C C     1 
ATOM   11562 O  O     . VAL C 1 437 ? -24.905 -6.693  -82.601  1.00 51.39  ? 437 VAL C O     1 
ATOM   11563 C  CB    . VAL C 1 437 ? -26.930 -4.846  -81.176  1.00 49.37  ? 437 VAL C CB    1 
ATOM   11564 C  CG1   . VAL C 1 437 ? -28.154 -5.699  -81.469  1.00 55.62  ? 437 VAL C CG1   1 
ATOM   11565 C  CG2   . VAL C 1 437 ? -27.271 -3.684  -80.260  1.00 47.58  ? 437 VAL C CG2   1 
ATOM   11566 N  N     . TYR C 1 438 ? -25.957 -8.070  -81.168  1.00 52.26  ? 438 TYR C N     1 
ATOM   11567 C  CA    . TYR C 1 438 ? -25.606 -9.292  -81.878  1.00 56.32  ? 438 TYR C CA    1 
ATOM   11568 C  C     . TYR C 1 438 ? -26.715 -10.326 -81.698  1.00 53.77  ? 438 TYR C C     1 
ATOM   11569 O  O     . TYR C 1 438 ? -27.393 -10.320 -80.677  1.00 62.07  ? 438 TYR C O     1 
ATOM   11570 C  CB    . TYR C 1 438 ? -24.291 -9.874  -81.352  1.00 51.87  ? 438 TYR C CB    1 
ATOM   11571 C  CG    . TYR C 1 438 ? -24.376 -10.324 -79.916  1.00 56.39  ? 438 TYR C CG    1 
ATOM   11572 C  CD1   . TYR C 1 438 ? -24.410 -9.383  -78.900  1.00 56.89  ? 438 TYR C CD1   1 
ATOM   11573 C  CD2   . TYR C 1 438 ? -24.509 -11.666 -79.571  1.00 55.86  ? 438 TYR C CD2   1 
ATOM   11574 C  CE1   . TYR C 1 438 ? -24.511 -9.756  -77.571  1.00 54.52  ? 438 TYR C CE1   1 
ATOM   11575 C  CE2   . TYR C 1 438 ? -24.636 -12.055 -78.245  1.00 53.80  ? 438 TYR C CE2   1 
ATOM   11576 C  CZ    . TYR C 1 438 ? -24.628 -11.092 -77.243  1.00 59.13  ? 438 TYR C CZ    1 
ATOM   11577 O  OH    . TYR C 1 438 ? -24.711 -11.364 -75.904  1.00 63.45  ? 438 TYR C OH    1 
ATOM   11578 N  N     . ASP C 1 439 ? -26.854 -11.232 -82.673  1.00 61.49  ? 439 ASP C N     1 
ATOM   11579 C  CA    . ASP C 1 439 ? -27.851 -12.289 -82.620  1.00 63.86  ? 439 ASP C CA    1 
ATOM   11580 C  C     . ASP C 1 439 ? -27.389 -13.338 -81.618  1.00 57.89  ? 439 ASP C C     1 
ATOM   11581 O  O     . ASP C 1 439 ? -26.516 -14.137 -81.931  1.00 47.81  ? 439 ASP C O     1 
ATOM   11582 C  CB    . ASP C 1 439 ? -28.082 -12.929 -83.992  1.00 68.30  ? 439 ASP C CB    1 
ATOM   11583 C  CG    . ASP C 1 439 ? -29.132 -14.030 -84.005  1.00 70.24  ? 439 ASP C CG    1 
ATOM   11584 O  OD1   . ASP C 1 439 ? -29.619 -14.408 -82.923  1.00 73.08  ? 439 ASP C OD1   1 
ATOM   11585 O  OD2   . ASP C 1 439 ? -29.462 -14.494 -85.101  1.00 67.14  ? 439 ASP C OD2   1 
ATOM   11586 N  N     . LYS C 1 440 ? -28.019 -13.341 -80.433  1.00 62.13  ? 440 LYS C N     1 
ATOM   11587 C  CA    . LYS C 1 440 ? -27.577 -14.185 -79.330  1.00 70.65  ? 440 LYS C CA    1 
ATOM   11588 C  C     . LYS C 1 440 ? -27.928 -15.654 -79.591  1.00 70.38  ? 440 LYS C C     1 
ATOM   11589 O  O     . LYS C 1 440 ? -27.465 -16.532 -78.862  1.00 61.31  ? 440 LYS C O     1 
ATOM   11590 C  CB    . LYS C 1 440 ? -28.195 -13.693 -78.016  1.00 74.70  ? 440 LYS C CB    1 
ATOM   11591 C  CG    . LYS C 1 440 ? -29.697 -13.912 -77.910  1.00 81.66  ? 440 LYS C CG    1 
ATOM   11592 C  CD    . LYS C 1 440 ? -30.454 -12.750 -77.308  1.00 91.63  ? 440 LYS C CD    1 
ATOM   11593 C  CE    . LYS C 1 440 ? -31.937 -12.799 -77.613  1.00 93.44  ? 440 LYS C CE    1 
ATOM   11594 N  NZ    . LYS C 1 440 ? -32.507 -14.130 -77.297  1.00 98.25  ? 440 LYS C NZ    1 
ATOM   11595 N  N     . THR C 1 441 ? -28.752 -15.918 -80.620  1.00 70.95  ? 441 THR C N     1 
ATOM   11596 C  CA    . THR C 1 441 ? -29.191 -17.274 -80.927  1.00 72.15  ? 441 THR C CA    1 
ATOM   11597 C  C     . THR C 1 441 ? -28.136 -18.024 -81.738  1.00 73.68  ? 441 THR C C     1 
ATOM   11598 O  O     . THR C 1 441 ? -28.148 -19.250 -81.754  1.00 75.53  ? 441 THR C O     1 
ATOM   11599 C  CB    . THR C 1 441 ? -30.519 -17.278 -81.693  1.00 66.49  ? 441 THR C CB    1 
ATOM   11600 O  OG1   . THR C 1 441 ? -30.269 -16.766 -83.002  1.00 70.72  ? 441 THR C OG1   1 
ATOM   11601 C  CG2   . THR C 1 441 ? -31.594 -16.460 -81.006  1.00 65.59  ? 441 THR C CG2   1 
ATOM   11602 N  N     . ASP C 1 442 ? -27.229 -17.288 -82.395  1.00 71.32  ? 442 ASP C N     1 
ATOM   11603 C  CA    . ASP C 1 442 ? -26.395 -17.847 -83.446  1.00 63.64  ? 442 ASP C CA    1 
ATOM   11604 C  C     . ASP C 1 442 ? -24.981 -18.085 -82.934  1.00 64.58  ? 442 ASP C C     1 
ATOM   11605 O  O     . ASP C 1 442 ? -24.270 -17.126 -82.655  1.00 64.89  ? 442 ASP C O     1 
ATOM   11606 C  CB    . ASP C 1 442 ? -26.339 -16.904 -84.644  1.00 62.84  ? 442 ASP C CB    1 
ATOM   11607 C  CG    . ASP C 1 442 ? -25.413 -17.375 -85.750  1.00 58.65  ? 442 ASP C CG    1 
ATOM   11608 O  OD1   . ASP C 1 442 ? -24.734 -18.401 -85.559  1.00 61.47  ? 442 ASP C OD1   1 
ATOM   11609 O  OD2   . ASP C 1 442 ? -25.364 -16.695 -86.783  1.00 63.78  ? 442 ASP C OD2   1 
ATOM   11610 N  N     . PRO C 1 443 ? -24.495 -19.349 -82.865  1.00 64.54  ? 443 PRO C N     1 
ATOM   11611 C  CA    . PRO C 1 443 ? -23.194 -19.638 -82.254  1.00 63.24  ? 443 PRO C CA    1 
ATOM   11612 C  C     . PRO C 1 443 ? -22.013 -18.995 -82.981  1.00 63.73  ? 443 PRO C C     1 
ATOM   11613 O  O     . PRO C 1 443 ? -20.959 -18.769 -82.382  1.00 58.35  ? 443 PRO C O     1 
ATOM   11614 C  CB    . PRO C 1 443 ? -23.104 -21.177 -82.295  1.00 65.43  ? 443 PRO C CB    1 
ATOM   11615 C  CG    . PRO C 1 443 ? -24.550 -21.629 -82.450  1.00 60.80  ? 443 PRO C CG    1 
ATOM   11616 C  CD    . PRO C 1 443 ? -25.167 -20.569 -83.337  1.00 59.83  ? 443 PRO C CD    1 
ATOM   11617 N  N     . ASP C 1 444 ? -22.196 -18.699 -84.274  1.00 61.75  ? 444 ASP C N     1 
ATOM   11618 C  CA    . ASP C 1 444 ? -21.137 -18.092 -85.057  1.00 71.80  ? 444 ASP C CA    1 
ATOM   11619 C  C     . ASP C 1 444 ? -21.039 -16.615 -84.694  1.00 63.69  ? 444 ASP C C     1 
ATOM   11620 O  O     . ASP C 1 444 ? -19.940 -16.103 -84.555  1.00 64.71  ? 444 ASP C O     1 
ATOM   11621 C  CB    . ASP C 1 444 ? -21.331 -18.319 -86.561  1.00 81.12  ? 444 ASP C CB    1 
ATOM   11622 C  CG    . ASP C 1 444 ? -21.291 -19.789 -86.952  1.00 79.15  ? 444 ASP C CG    1 
ATOM   11623 O  OD1   . ASP C 1 444 ? -20.337 -20.469 -86.540  1.00 81.48  ? 444 ASP C OD1   1 
ATOM   11624 O  OD2   . ASP C 1 444 ? -22.222 -20.247 -87.645  1.00 73.70  ? 444 ASP C OD2   1 
ATOM   11625 N  N     . GLU C 1 445 ? -22.180 -15.931 -84.555  1.00 60.66  ? 445 GLU C N     1 
ATOM   11626 C  CA    . GLU C 1 445 ? -22.190 -14.561 -84.067  1.00 61.17  ? 445 GLU C CA    1 
ATOM   11627 C  C     . GLU C 1 445 ? -21.594 -14.489 -82.658  1.00 63.64  ? 445 GLU C C     1 
ATOM   11628 O  O     . GLU C 1 445 ? -20.663 -13.721 -82.400  1.00 56.94  ? 445 GLU C O     1 
ATOM   11629 C  CB    . GLU C 1 445 ? -23.613 -14.023 -84.103  1.00 64.16  ? 445 GLU C CB    1 
ATOM   11630 C  CG    . GLU C 1 445 ? -24.066 -13.749 -85.504  1.00 65.42  ? 445 GLU C CG    1 
ATOM   11631 C  CD    . GLU C 1 445 ? -23.241 -12.649 -86.121  1.00 74.07  ? 445 GLU C CD    1 
ATOM   11632 O  OE1   . GLU C 1 445 ? -23.384 -11.502 -85.646  1.00 85.66  ? 445 GLU C OE1   1 
ATOM   11633 O  OE2   . GLU C 1 445 ? -22.427 -12.956 -87.022  1.00 79.25  ? 445 GLU C OE2   1 
ATOM   11634 N  N     . ARG C 1 446 ? -22.097 -15.342 -81.763  1.00 56.64  ? 446 ARG C N     1 
ATOM   11635 C  CA    . ARG C 1 446 ? -21.613 -15.367 -80.397  1.00 58.38  ? 446 ARG C CA    1 
ATOM   11636 C  C     . ARG C 1 446 ? -20.096 -15.551 -80.384  1.00 59.45  ? 446 ARG C C     1 
ATOM   11637 O  O     . ARG C 1 446 ? -19.420 -14.873 -79.623  1.00 56.51  ? 446 ARG C O     1 
ATOM   11638 C  CB    . ARG C 1 446 ? -22.307 -16.459 -79.582  1.00 55.54  ? 446 ARG C CB    1 
ATOM   11639 C  CG    . ARG C 1 446 ? -23.813 -16.286 -79.448  1.00 59.51  ? 446 ARG C CG    1 
ATOM   11640 C  CD    . ARG C 1 446 ? -24.366 -17.213 -78.379  1.00 62.21  ? 446 ARG C CD    1 
ATOM   11641 N  NE    . ARG C 1 446 ? -24.081 -18.623 -78.608  1.00 59.75  ? 446 ARG C NE    1 
ATOM   11642 C  CZ    . ARG C 1 446 ? -25.008 -19.568 -78.721  1.00 64.07  ? 446 ARG C CZ    1 
ATOM   11643 N  NH1   . ARG C 1 446 ? -26.289 -19.260 -78.604  1.00 61.93  ? 446 ARG C NH1   1 
ATOM   11644 N  NH2   . ARG C 1 446 ? -24.651 -20.819 -78.962  1.00 67.70  ? 446 ARG C NH2   1 
ATOM   11645 N  N     . LYS C 1 447 ? -19.562 -16.470 -81.200  1.00 63.65  ? 447 LYS C N     1 
ATOM   11646 C  CA    . LYS C 1 447 ? -18.124 -16.694 -81.238  1.00 63.38  ? 447 LYS C CA    1 
ATOM   11647 C  C     . LYS C 1 447 ? -17.417 -15.411 -81.672  1.00 56.69  ? 447 LYS C C     1 
ATOM   11648 O  O     . LYS C 1 447 ? -16.417 -15.043 -81.075  1.00 60.57  ? 447 LYS C O     1 
ATOM   11649 C  CB    . LYS C 1 447 ? -17.746 -17.859 -82.156  1.00 67.56  ? 447 LYS C CB    1 
ATOM   11650 C  CG    . LYS C 1 447 ? -16.252 -18.175 -82.194  1.00 72.36  ? 447 LYS C CG    1 
ATOM   11651 C  CD    . LYS C 1 447 ? -15.950 -19.662 -82.198  1.00 82.96  ? 447 LYS C CD    1 
ATOM   11652 C  CE    . LYS C 1 447 ? -14.487 -20.000 -82.000  1.00 87.04  ? 447 LYS C CE    1 
ATOM   11653 N  NZ    . LYS C 1 447 ? -13.719 -19.883 -83.261  1.00 88.02  ? 447 LYS C NZ    1 
ATOM   11654 N  N     . LYS C 1 448 ? -17.953 -14.734 -82.691  1.00 57.99  ? 448 LYS C N     1 
ATOM   11655 C  CA    . LYS C 1 448 ? -17.381 -13.492 -83.178  1.00 61.04  ? 448 LYS C CA    1 
ATOM   11656 C  C     . LYS C 1 448 ? -17.389 -12.451 -82.059  1.00 58.62  ? 448 LYS C C     1 
ATOM   11657 O  O     . LYS C 1 448 ? -16.409 -11.738 -81.877  1.00 54.95  ? 448 LYS C O     1 
ATOM   11658 C  CB    . LYS C 1 448 ? -18.130 -12.953 -84.401  1.00 59.36  ? 448 LYS C CB    1 
ATOM   11659 C  CG    . LYS C 1 448 ? -17.765 -13.615 -85.725  1.00 73.65  ? 448 LYS C CG    1 
ATOM   11660 C  CD    . LYS C 1 448 ? -18.700 -13.294 -86.883  1.00 73.83  ? 448 LYS C CD    1 
ATOM   11661 C  CE    . LYS C 1 448 ? -18.838 -11.814 -87.158  1.00 82.21  ? 448 LYS C CE    1 
ATOM   11662 N  NZ    . LYS C 1 448 ? -19.651 -11.557 -88.369  1.00 83.76  ? 448 LYS C NZ    1 
ATOM   11663 N  N     . LEU C 1 449 ? -18.498 -12.362 -81.318  1.00 56.90  ? 449 LEU C N     1 
ATOM   11664 C  CA    . LEU C 1 449 ? -18.645 -11.322 -80.313  1.00 56.73  ? 449 LEU C CA    1 
ATOM   11665 C  C     . LEU C 1 449 ? -17.599 -11.499 -79.219  1.00 51.15  ? 449 LEU C C     1 
ATOM   11666 O  O     . LEU C 1 449 ? -16.883 -10.561 -78.880  1.00 52.88  ? 449 LEU C O     1 
ATOM   11667 C  CB    . LEU C 1 449 ? -20.042 -11.355 -79.703  1.00 59.87  ? 449 LEU C CB    1 
ATOM   11668 C  CG    . LEU C 1 449 ? -20.262 -10.246 -78.676  1.00 61.57  ? 449 LEU C CG    1 
ATOM   11669 C  CD1   . LEU C 1 449 ? -20.603 -8.938  -79.374  1.00 59.82  ? 449 LEU C CD1   1 
ATOM   11670 C  CD2   . LEU C 1 449 ? -21.332 -10.642 -77.685  1.00 69.63  ? 449 LEU C CD2   1 
ATOM   11671 N  N     . ASP C 1 450 ? -17.538 -12.723 -78.699  1.00 51.37  ? 450 ASP C N     1 
ATOM   11672 C  CA    . ASP C 1 450 ? -16.559 -13.157 -77.724  1.00 53.07  ? 450 ASP C CA    1 
ATOM   11673 C  C     . ASP C 1 450 ? -15.149 -12.732 -78.143  1.00 57.27  ? 450 ASP C C     1 
ATOM   11674 O  O     . ASP C 1 450 ? -14.375 -12.235 -77.328  1.00 50.11  ? 450 ASP C O     1 
ATOM   11675 C  CB    . ASP C 1 450 ? -16.662 -14.672 -77.581  1.00 52.49  ? 450 ASP C CB    1 
ATOM   11676 C  CG    . ASP C 1 450 ? -15.863 -15.226 -76.430  1.00 59.10  ? 450 ASP C CG    1 
ATOM   11677 O  OD1   . ASP C 1 450 ? -15.496 -14.442 -75.541  1.00 70.40  ? 450 ASP C OD1   1 
ATOM   11678 O  OD2   . ASP C 1 450 ? -15.619 -16.434 -76.439  1.00 64.99  ? 450 ASP C OD2   1 
ATOM   11679 N  N     . GLU C 1 451 ? -14.817 -12.950 -79.421  1.00 51.52  ? 451 GLU C N     1 
ATOM   11680 C  CA    . GLU C 1 451 ? -13.475 -12.713 -79.924  1.00 56.92  ? 451 GLU C CA    1 
ATOM   11681 C  C     . GLU C 1 451 ? -13.237 -11.206 -80.010  1.00 51.09  ? 451 GLU C C     1 
ATOM   11682 O  O     . GLU C 1 451 ? -12.195 -10.709 -79.596  1.00 50.78  ? 451 GLU C O     1 
ATOM   11683 C  CB    . GLU C 1 451 ? -13.331 -13.408 -81.276  1.00 64.69  ? 451 GLU C CB    1 
ATOM   11684 C  CG    . GLU C 1 451 ? -11.910 -13.493 -81.784  1.00 72.31  ? 451 GLU C CG    1 
ATOM   11685 C  CD    . GLU C 1 451 ? -11.840 -13.929 -83.240  1.00 90.29  ? 451 GLU C CD    1 
ATOM   11686 O  OE1   . GLU C 1 451 ? -12.398 -15.012 -83.551  1.00 94.33  ? 451 GLU C OE1   1 
ATOM   11687 O  OE2   . GLU C 1 451 ? -11.258 -13.176 -84.070  1.00 77.87  ? 451 GLU C OE2   1 
ATOM   11688 N  N     . LEU C 1 452 ? -14.233 -10.489 -80.528  1.00 46.77  ? 452 LEU C N     1 
ATOM   11689 C  CA    . LEU C 1 452 ? -14.227 -9.036  -80.580  1.00 50.48  ? 452 LEU C CA    1 
ATOM   11690 C  C     . LEU C 1 452 ? -14.052 -8.452  -79.177  1.00 52.22  ? 452 LEU C C     1 
ATOM   11691 O  O     . LEU C 1 452 ? -13.234 -7.575  -78.947  1.00 47.28  ? 452 LEU C O     1 
ATOM   11692 C  CB    . LEU C 1 452 ? -15.552 -8.586  -81.196  1.00 46.51  ? 452 LEU C CB    1 
ATOM   11693 C  CG    . LEU C 1 452 ? -15.850 -7.089  -81.115  1.00 47.49  ? 452 LEU C CG    1 
ATOM   11694 C  CD1   . LEU C 1 452 ? -14.693 -6.265  -81.678  1.00 48.09  ? 452 LEU C CD1   1 
ATOM   11695 C  CD2   . LEU C 1 452 ? -17.138 -6.786  -81.859  1.00 47.95  ? 452 LEU C CD2   1 
ATOM   11696 N  N     . PHE C 1 453 ? -14.826 -8.952  -78.225  1.00 47.63  ? 453 PHE C N     1 
ATOM   11697 C  CA    . PHE C 1 453 ? -14.796 -8.375  -76.898  1.00 51.55  ? 453 PHE C CA    1 
ATOM   11698 C  C     . PHE C 1 453 ? -13.404 -8.529  -76.292  1.00 49.39  ? 453 PHE C C     1 
ATOM   11699 O  O     . PHE C 1 453 ? -12.917 -7.593  -75.658  1.00 40.52  ? 453 PHE C O     1 
ATOM   11700 C  CB    . PHE C 1 453 ? -15.895 -8.979  -76.019  1.00 51.95  ? 453 PHE C CB    1 
ATOM   11701 C  CG    . PHE C 1 453 ? -16.213 -8.119  -74.827  1.00 51.49  ? 453 PHE C CG    1 
ATOM   11702 C  CD1   . PHE C 1 453 ? -15.448 -8.208  -73.665  1.00 54.01  ? 453 PHE C CD1   1 
ATOM   11703 C  CD2   . PHE C 1 453 ? -17.210 -7.161  -74.899  1.00 53.62  ? 453 PHE C CD2   1 
ATOM   11704 C  CE1   . PHE C 1 453 ? -15.722 -7.392  -72.579  1.00 50.52  ? 453 PHE C CE1   1 
ATOM   11705 C  CE2   . PHE C 1 453 ? -17.475 -6.344  -73.811  1.00 51.81  ? 453 PHE C CE2   1 
ATOM   11706 C  CZ    . PHE C 1 453 ? -16.731 -6.457  -72.661  1.00 46.84  ? 453 PHE C CZ    1 
ATOM   11707 N  N     . ASN C 1 454 ? -12.786 -9.713  -76.461  1.00 46.96  ? 454 ASN C N     1 
ATOM   11708 C  CA    . ASN C 1 454 ? -11.448 -9.947  -75.939  1.00 48.85  ? 454 ASN C CA    1 
ATOM   11709 C  C     . ASN C 1 454 ? -10.448 -8.963  -76.538  1.00 50.98  ? 454 ASN C C     1 
ATOM   11710 O  O     . ASN C 1 454 ? -9.579  -8.503  -75.808  1.00 49.30  ? 454 ASN C O     1 
ATOM   11711 C  CB    . ASN C 1 454 ? -10.985 -11.393 -76.107  1.00 51.39  ? 454 ASN C CB    1 
ATOM   11712 C  CG    . ASN C 1 454 ? -11.787 -12.307 -75.201  1.00 56.95  ? 454 ASN C CG    1 
ATOM   11713 O  OD1   . ASN C 1 454 ? -12.165 -11.907 -74.103  1.00 60.00  ? 454 ASN C OD1   1 
ATOM   11714 N  ND2   . ASN C 1 454 ? -12.130 -13.495 -75.668  1.00 60.84  ? 454 ASN C ND2   1 
ATOM   11715 N  N     . ILE C 1 455 ? -10.582 -8.661  -77.842  1.00 44.32  ? 455 ILE C N     1 
ATOM   11716 C  CA    . ILE C 1 455 ? -9.696  -7.744  -78.538  1.00 49.72  ? 455 ILE C CA    1 
ATOM   11717 C  C     . ILE C 1 455 ? -9.851  -6.339  -77.934  1.00 46.26  ? 455 ILE C C     1 
ATOM   11718 O  O     . ILE C 1 455 ? -8.864  -5.685  -77.606  1.00 41.60  ? 455 ILE C O     1 
ATOM   11719 C  CB    . ILE C 1 455 ? -9.974  -7.787  -80.066  1.00 50.12  ? 455 ILE C CB    1 
ATOM   11720 C  CG1   . ILE C 1 455 ? -9.535  -9.123  -80.675  1.00 56.62  ? 455 ILE C CG1   1 
ATOM   11721 C  CG2   . ILE C 1 455 ? -9.333  -6.625  -80.808  1.00 45.47  ? 455 ILE C CG2   1 
ATOM   11722 C  CD1   . ILE C 1 455 ? -9.872  -9.294  -82.157  1.00 55.86  ? 455 ILE C CD1   1 
ATOM   11723 N  N     . LEU C 1 456 ? -11.097 -5.863  -77.820  1.00 43.00  ? 456 LEU C N     1 
ATOM   11724 C  CA    . LEU C 1 456 ? -11.385 -4.536  -77.282  1.00 46.23  ? 456 LEU C CA    1 
ATOM   11725 C  C     . LEU C 1 456 ? -10.761 -4.364  -75.893  1.00 47.40  ? 456 LEU C C     1 
ATOM   11726 O  O     . LEU C 1 456 ? -10.219 -3.306  -75.586  1.00 49.12  ? 456 LEU C O     1 
ATOM   11727 C  CB    . LEU C 1 456 ? -12.907 -4.350  -77.210  1.00 48.04  ? 456 LEU C CB    1 
ATOM   11728 C  CG    . LEU C 1 456 ? -13.639 -4.238  -78.546  1.00 48.72  ? 456 LEU C CG    1 
ATOM   11729 C  CD1   . LEU C 1 456 ? -15.149 -4.134  -78.341  1.00 48.42  ? 456 LEU C CD1   1 
ATOM   11730 C  CD2   . LEU C 1 456 ? -13.140 -3.035  -79.324  1.00 49.03  ? 456 LEU C CD2   1 
ATOM   11731 N  N     . VAL C 1 457 ? -10.859 -5.405  -75.047  1.00 48.94  ? 457 VAL C N     1 
ATOM   11732 C  CA    . VAL C 1 457 ? -10.354 -5.340  -73.679  1.00 48.13  ? 457 VAL C CA    1 
ATOM   11733 C  C     . VAL C 1 457 ? -8.823  -5.272  -73.727  1.00 47.12  ? 457 VAL C C     1 
ATOM   11734 O  O     . VAL C 1 457 ? -8.219  -4.422  -73.087  1.00 42.52  ? 457 VAL C O     1 
ATOM   11735 C  CB    . VAL C 1 457 ? -10.861 -6.531  -72.829  1.00 47.93  ? 457 VAL C CB    1 
ATOM   11736 C  CG1   . VAL C 1 457 ? -10.007 -6.768  -71.586  1.00 46.88  ? 457 VAL C CG1   1 
ATOM   11737 C  CG2   . VAL C 1 457 ? -12.345 -6.414  -72.453  1.00 45.54  ? 457 VAL C CG2   1 
ATOM   11738 N  N     . ASP C 1 458 ? -8.205  -6.180  -74.492  1.00 45.97  ? 458 ASP C N     1 
ATOM   11739 C  CA    . ASP C 1 458 ? -6.760  -6.260  -74.604  1.00 44.62  ? 458 ASP C CA    1 
ATOM   11740 C  C     . ASP C 1 458 ? -6.235  -4.934  -75.149  1.00 40.34  ? 458 ASP C C     1 
ATOM   11741 O  O     . ASP C 1 458 ? -5.311  -4.379  -74.581  1.00 43.72  ? 458 ASP C O     1 
ATOM   11742 C  CB    . ASP C 1 458 ? -6.336  -7.479  -75.422  1.00 46.73  ? 458 ASP C CB    1 
ATOM   11743 C  CG    . ASP C 1 458 ? -6.749  -8.821  -74.823  1.00 54.82  ? 458 ASP C CG    1 
ATOM   11744 O  OD1   . ASP C 1 458 ? -7.156  -8.867  -73.637  1.00 63.29  ? 458 ASP C OD1   1 
ATOM   11745 O  OD2   . ASP C 1 458 ? -6.695  -9.821  -75.557  1.00 55.80  ? 458 ASP C OD2   1 
ATOM   11746 N  N     . GLU C 1 459 ? -6.885  -4.385  -76.174  1.00 47.19  ? 459 GLU C N     1 
ATOM   11747 C  CA    . GLU C 1 459 ? -6.359  -3.222  -76.881  1.00 50.44  ? 459 GLU C CA    1 
ATOM   11748 C  C     . GLU C 1 459 ? -6.467  -1.968  -76.030  1.00 46.03  ? 459 GLU C C     1 
ATOM   11749 O  O     . GLU C 1 459 ? -5.513  -1.189  -75.968  1.00 41.52  ? 459 GLU C O     1 
ATOM   11750 C  CB    . GLU C 1 459 ? -7.054  -2.987  -78.233  1.00 53.22  ? 459 GLU C CB    1 
ATOM   11751 C  CG    . GLU C 1 459 ? -6.624  -4.012  -79.279  1.00 56.80  ? 459 GLU C CG    1 
ATOM   11752 C  CD    . GLU C 1 459 ? -7.029  -3.793  -80.731  1.00 56.37  ? 459 GLU C CD    1 
ATOM   11753 O  OE1   . GLU C 1 459 ? -7.929  -2.990  -81.020  1.00 60.32  ? 459 GLU C OE1   1 
ATOM   11754 O  OE2   . GLU C 1 459 ? -6.409  -4.425  -81.580  1.00 54.71  ? 459 GLU C OE2   1 
ATOM   11755 N  N     . ALA C 1 460 ? -7.657  -1.761  -75.451  1.00 44.35  ? 460 ALA C N     1 
ATOM   11756 C  CA    . ALA C 1 460 ? -7.903  -0.674  -74.514  1.00 45.45  ? 460 ALA C CA    1 
ATOM   11757 C  C     . ALA C 1 460 ? -6.884  -0.702  -73.372  1.00 42.02  ? 460 ALA C C     1 
ATOM   11758 O  O     . ALA C 1 460 ? -6.338  0.333   -72.999  1.00 44.57  ? 460 ALA C O     1 
ATOM   11759 C  CB    . ALA C 1 460 ? -9.311  -0.760  -73.975  1.00 43.18  ? 460 ALA C CB    1 
ATOM   11760 N  N     . ALA C 1 461 ? -6.643  -1.884  -72.812  1.00 37.36  ? 461 ALA C N     1 
ATOM   11761 C  CA    . ALA C 1 461 ? -5.771  -1.995  -71.652  1.00 42.96  ? 461 ALA C CA    1 
ATOM   11762 C  C     . ALA C 1 461 ? -4.312  -1.685  -72.025  1.00 51.50  ? 461 ALA C C     1 
ATOM   11763 O  O     . ALA C 1 461 ? -3.555  -1.080  -71.250  1.00 45.71  ? 461 ALA C O     1 
ATOM   11764 C  CB    . ALA C 1 461 ? -5.899  -3.377  -71.091  1.00 40.43  ? 461 ALA C CB    1 
ATOM   11765 N  N     . ALA C 1 462 ? -3.915  -2.121  -73.222  1.00 46.13  ? 462 ALA C N     1 
ATOM   11766 C  CA    . ALA C 1 462 ? -2.582  -1.852  -73.727  1.00 44.68  ? 462 ALA C CA    1 
ATOM   11767 C  C     . ALA C 1 462 ? -2.385  -0.343  -73.863  1.00 41.36  ? 462 ALA C C     1 
ATOM   11768 O  O     . ALA C 1 462 ? -1.271  0.139   -73.734  1.00 46.83  ? 462 ALA C O     1 
ATOM   11769 C  CB    . ALA C 1 462 ? -2.371  -2.601  -75.027  1.00 48.14  ? 462 ALA C CB    1 
ATOM   11770 N  N     . GLU C 1 463 ? -3.462  0.433   -74.038  1.00 44.79  ? 463 GLU C N     1 
ATOM   11771 C  CA    . GLU C 1 463 ? -3.306  1.879   -74.137  1.00 45.29  ? 463 GLU C CA    1 
ATOM   11772 C  C     . GLU C 1 463 ? -3.343  2.541   -72.759  1.00 47.30  ? 463 GLU C C     1 
ATOM   11773 O  O     . GLU C 1 463 ? -3.111  3.748   -72.673  1.00 48.84  ? 463 GLU C O     1 
ATOM   11774 C  CB    . GLU C 1 463 ? -4.377  2.531   -75.016  1.00 45.27  ? 463 GLU C CB    1 
ATOM   11775 C  CG    . GLU C 1 463 ? -4.447  2.026   -76.460  1.00 47.75  ? 463 GLU C CG    1 
ATOM   11776 C  CD    . GLU C 1 463 ? -3.207  2.253   -77.316  1.00 52.58  ? 463 GLU C CD    1 
ATOM   11777 O  OE1   . GLU C 1 463 ? -2.597  3.326   -77.177  1.00 44.79  ? 463 GLU C OE1   1 
ATOM   11778 O  OE2   . GLU C 1 463 ? -2.867  1.360   -78.134  1.00 54.63  ? 463 GLU C OE2   1 
ATOM   11779 N  N     . GLY C 1 464 ? -3.651  1.770   -71.703  1.00 42.44  ? 464 GLY C N     1 
ATOM   11780 C  CA    . GLY C 1 464 ? -3.842  2.316   -70.366  1.00 47.37  ? 464 GLY C CA    1 
ATOM   11781 C  C     . GLY C 1 464 ? -5.293  2.703   -70.050  1.00 44.73  ? 464 GLY C C     1 
ATOM   11782 O  O     . GLY C 1 464 ? -5.545  3.560   -69.198  1.00 48.27  ? 464 GLY C O     1 
ATOM   11783 N  N     . TYR C 1 465 ? -6.250  2.072   -70.738  1.00 43.07  ? 465 TYR C N     1 
ATOM   11784 C  CA    . TYR C 1 465 ? -7.667  2.298   -70.477  1.00 40.22  ? 465 TYR C CA    1 
ATOM   11785 C  C     . TYR C 1 465 ? -8.276  1.042   -69.865  1.00 40.63  ? 465 TYR C C     1 
ATOM   11786 O  O     . TYR C 1 465 ? -8.201  -0.031  -70.455  1.00 39.48  ? 465 TYR C O     1 
ATOM   11787 C  CB    . TYR C 1 465 ? -8.432  2.628   -71.761  1.00 40.72  ? 465 TYR C CB    1 
ATOM   11788 C  CG    . TYR C 1 465 ? -7.987  3.863   -72.508  1.00 40.01  ? 465 TYR C CG    1 
ATOM   11789 C  CD1   . TYR C 1 465 ? -7.688  5.048   -71.853  1.00 41.05  ? 465 TYR C CD1   1 
ATOM   11790 C  CD2   . TYR C 1 465 ? -7.893  3.847   -73.893  1.00 40.72  ? 465 TYR C CD2   1 
ATOM   11791 C  CE1   . TYR C 1 465 ? -7.285  6.176   -72.553  1.00 49.04  ? 465 TYR C CE1   1 
ATOM   11792 C  CE2   . TYR C 1 465 ? -7.530  4.972   -74.611  1.00 39.70  ? 465 TYR C CE2   1 
ATOM   11793 C  CZ    . TYR C 1 465 ? -7.206  6.131   -73.941  1.00 47.52  ? 465 TYR C CZ    1 
ATOM   11794 O  OH    . TYR C 1 465 ? -6.821  7.198   -74.692  1.00 45.31  ? 465 TYR C OH    1 
ATOM   11795 N  N     . GLY C 1 466 ? -8.879  1.179   -68.673  1.00 43.40  ? 466 GLY C N     1 
ATOM   11796 C  CA    . GLY C 1 466 ? -9.543  0.067   -68.013  1.00 39.72  ? 466 GLY C CA    1 
ATOM   11797 C  C     . GLY C 1 466 ? -11.055 0.238   -67.974  1.00 39.43  ? 466 GLY C C     1 
ATOM   11798 O  O     . GLY C 1 466 ? -11.534 1.363   -67.987  1.00 44.40  ? 466 GLY C O     1 
ATOM   11799 N  N     . GLU C 1 467 ? -11.780 -0.883  -67.847  1.00 40.16  ? 467 GLU C N     1 
ATOM   11800 C  CA    . GLU C 1 467 ? -13.240 -0.900  -67.794  1.00 44.23  ? 467 GLU C CA    1 
ATOM   11801 C  C     . GLU C 1 467 ? -13.741 -0.670  -66.355  1.00 45.44  ? 467 GLU C C     1 
ATOM   11802 O  O     . GLU C 1 467 ? -13.131 -1.135  -65.406  1.00 41.54  ? 467 GLU C O     1 
ATOM   11803 C  CB    . GLU C 1 467 ? -13.775 -2.227  -68.358  1.00 51.83  ? 467 GLU C CB    1 
ATOM   11804 C  CG    . GLU C 1 467 ? -13.722 -2.323  -69.893  1.00 59.14  ? 467 GLU C CG    1 
ATOM   11805 C  CD    . GLU C 1 467 ? -12.346 -2.541  -70.521  1.00 56.24  ? 467 GLU C CD    1 
ATOM   11806 O  OE1   . GLU C 1 467 ? -11.711 -1.558  -70.999  1.00 58.44  ? 467 GLU C OE1   1 
ATOM   11807 O  OE2   . GLU C 1 467 ? -11.909 -3.694  -70.542  1.00 54.20  ? 467 GLU C OE2   1 
ATOM   11808 N  N     . TYR C 1 468 ? -14.864 0.051   -66.195  1.00 46.70  ? 468 TYR C N     1 
ATOM   11809 C  CA    . TYR C 1 468 ? -15.440 0.314   -64.877  1.00 51.25  ? 468 TYR C CA    1 
ATOM   11810 C  C     . TYR C 1 468 ? -16.442 -0.778  -64.501  1.00 46.26  ? 468 TYR C C     1 
ATOM   11811 O  O     . TYR C 1 468 ? -16.773 -0.938  -63.332  1.00 43.14  ? 468 TYR C O     1 
ATOM   11812 C  CB    . TYR C 1 468 ? -16.129 1.686   -64.818  1.00 49.86  ? 468 TYR C CB    1 
ATOM   11813 C  CG    . TYR C 1 468 ? -17.606 1.704   -65.127  1.00 58.26  ? 468 TYR C CG    1 
ATOM   11814 C  CD1   . TYR C 1 468 ? -18.091 1.808   -66.421  1.00 63.70  ? 468 TYR C CD1   1 
ATOM   11815 C  CD2   . TYR C 1 468 ? -18.537 1.625   -64.105  1.00 62.51  ? 468 TYR C CD2   1 
ATOM   11816 C  CE1   . TYR C 1 468 ? -19.456 1.828   -66.691  1.00 69.63  ? 468 TYR C CE1   1 
ATOM   11817 C  CE2   . TYR C 1 468 ? -19.900 1.639   -64.358  1.00 63.88  ? 468 TYR C CE2   1 
ATOM   11818 C  CZ    . TYR C 1 468 ? -20.373 1.744   -65.654  1.00 69.77  ? 468 TYR C CZ    1 
ATOM   11819 O  OH    . TYR C 1 468 ? -21.753 1.736   -65.850  1.00 72.96  ? 468 TYR C OH    1 
ATOM   11820 N  N     . ARG C 1 469 ? -16.922 -1.518  -65.507  1.00 46.22  ? 469 ARG C N     1 
ATOM   11821 C  CA    . ARG C 1 469 ? -17.963 -2.513  -65.326  1.00 46.13  ? 469 ARG C CA    1 
ATOM   11822 C  C     . ARG C 1 469 ? -17.910 -3.524  -66.467  1.00 49.04  ? 469 ARG C C     1 
ATOM   11823 O  O     . ARG C 1 469 ? -17.486 -3.166  -67.560  1.00 53.13  ? 469 ARG C O     1 
ATOM   11824 C  CB    . ARG C 1 469 ? -19.302 -1.789  -65.301  1.00 47.00  ? 469 ARG C CB    1 
ATOM   11825 C  CG    . ARG C 1 469 ? -20.430 -2.613  -64.719  1.00 53.93  ? 469 ARG C CG    1 
ATOM   11826 C  CD    . ARG C 1 469 ? -21.630 -1.694  -64.716  1.00 56.63  ? 469 ARG C CD    1 
ATOM   11827 N  NE    . ARG C 1 469 ? -22.831 -2.387  -64.322  1.00 56.85  ? 469 ARG C NE    1 
ATOM   11828 C  CZ    . ARG C 1 469 ? -24.027 -1.820  -64.290  1.00 58.20  ? 469 ARG C CZ    1 
ATOM   11829 N  NH1   . ARG C 1 469 ? -24.135 -0.546  -64.629  1.00 49.33  ? 469 ARG C NH1   1 
ATOM   11830 N  NH2   . ARG C 1 469 ? -25.091 -2.533  -63.934  1.00 57.63  ? 469 ARG C NH2   1 
ATOM   11831 N  N     . THR C 1 470 ? -18.323 -4.777  -66.205  1.00 48.20  ? 470 THR C N     1 
ATOM   11832 C  CA    . THR C 1 470 ? -18.274 -5.807  -67.234  1.00 53.94  ? 470 THR C CA    1 
ATOM   11833 C  C     . THR C 1 470 ? -19.229 -6.974  -66.968  1.00 50.10  ? 470 THR C C     1 
ATOM   11834 O  O     . THR C 1 470 ? -19.761 -7.144  -65.891  1.00 46.22  ? 470 THR C O     1 
ATOM   11835 C  CB    . THR C 1 470 ? -16.850 -6.356  -67.408  1.00 51.60  ? 470 THR C CB    1 
ATOM   11836 O  OG1   . THR C 1 470 ? -16.807 -7.005  -68.679  1.00 53.48  ? 470 THR C OG1   1 
ATOM   11837 C  CG2   . THR C 1 470 ? -16.427 -7.316  -66.318  1.00 47.09  ? 470 THR C CG2   1 
ATOM   11838 N  N     . HIS C 1 471 ? -19.413 -7.775  -68.015  1.00 53.45  ? 471 HIS C N     1 
ATOM   11839 C  CA    . HIS C 1 471 ? -20.199 -8.992  -68.017  1.00 48.31  ? 471 HIS C CA    1 
ATOM   11840 C  C     . HIS C 1 471 ? -19.463 -10.050 -67.204  1.00 46.86  ? 471 HIS C C     1 
ATOM   11841 O  O     . HIS C 1 471 ? -18.233 -10.118 -67.226  1.00 47.40  ? 471 HIS C O     1 
ATOM   11842 C  CB    . HIS C 1 471 ? -20.458 -9.369  -69.488  1.00 52.40  ? 471 HIS C CB    1 
ATOM   11843 C  CG    . HIS C 1 471 ? -21.373 -10.528 -69.724  1.00 56.17  ? 471 HIS C CG    1 
ATOM   11844 N  ND1   . HIS C 1 471 ? -21.082 -11.842 -69.408  1.00 52.65  ? 471 HIS C ND1   1 
ATOM   11845 C  CD2   . HIS C 1 471 ? -22.603 -10.536 -70.272  1.00 54.93  ? 471 HIS C CD2   1 
ATOM   11846 C  CE1   . HIS C 1 471 ? -22.116 -12.608 -69.743  1.00 48.58  ? 471 HIS C CE1   1 
ATOM   11847 N  NE2   . HIS C 1 471 ? -23.045 -11.838 -70.269  1.00 53.18  ? 471 HIS C NE2   1 
ATOM   11848 N  N     . ILE C 1 472 ? -20.241 -10.908 -66.531  1.00 47.27  ? 472 ILE C N     1 
ATOM   11849 C  CA    . ILE C 1 472 ? -19.724 -12.027 -65.746  1.00 49.09  ? 472 ILE C CA    1 
ATOM   11850 C  C     . ILE C 1 472 ? -18.664 -12.814 -66.503  1.00 50.16  ? 472 ILE C C     1 
ATOM   11851 O  O     . ILE C 1 472 ? -17.746 -13.377 -65.898  1.00 51.72  ? 472 ILE C O     1 
ATOM   11852 C  CB    . ILE C 1 472 ? -20.853 -12.987 -65.316  1.00 54.07  ? 472 ILE C CB    1 
ATOM   11853 C  CG1   . ILE C 1 472 ? -21.634 -13.513 -66.524  1.00 54.21  ? 472 ILE C CG1   1 
ATOM   11854 C  CG2   . ILE C 1 472 ? -21.770 -12.340 -64.289  1.00 51.28  ? 472 ILE C CG2   1 
ATOM   11855 C  CD1   . ILE C 1 472 ? -22.673 -14.549 -66.191  1.00 58.22  ? 472 ILE C CD1   1 
ATOM   11856 N  N     . ARG C 1 473 ? -18.820 -12.909 -67.822  1.00 52.34  ? 473 ARG C N     1 
ATOM   11857 C  CA    . ARG C 1 473 ? -17.928 -13.744 -68.601  1.00 51.45  ? 473 ARG C CA    1 
ATOM   11858 C  C     . ARG C 1 473 ? -16.513 -13.176 -68.539  1.00 48.35  ? 473 ARG C C     1 
ATOM   11859 O  O     . ARG C 1 473 ? -15.560 -13.936 -68.489  1.00 50.19  ? 473 ARG C O     1 
ATOM   11860 C  CB    . ARG C 1 473 ? -18.454 -13.850 -70.034  1.00 65.17  ? 473 ARG C CB    1 
ATOM   11861 C  CG    . ARG C 1 473 ? -17.615 -14.740 -70.939  1.00 69.57  ? 473 ARG C CG    1 
ATOM   11862 C  CD    . ARG C 1 473 ? -18.345 -15.034 -72.236  1.00 75.20  ? 473 ARG C CD    1 
ATOM   11863 N  NE    . ARG C 1 473 ? -17.520 -15.791 -73.168  1.00 71.91  ? 473 ARG C NE    1 
ATOM   11864 C  CZ    . ARG C 1 473 ? -17.132 -17.051 -72.996  1.00 71.79  ? 473 ARG C CZ    1 
ATOM   11865 N  NH1   . ARG C 1 473 ? -17.583 -17.767 -71.976  1.00 65.55  ? 473 ARG C NH1   1 
ATOM   11866 N  NH2   . ARG C 1 473 ? -16.307 -17.596 -73.876  1.00 68.96  ? 473 ARG C NH2   1 
ATOM   11867 N  N     . TYR C 1 474 ? -16.390 -11.843 -68.476  1.00 48.59  ? 474 TYR C N     1 
ATOM   11868 C  CA    . TYR C 1 474 ? -15.123 -11.173 -68.683  1.00 48.58  ? 474 TYR C CA    1 
ATOM   11869 C  C     . TYR C 1 474 ? -14.516 -10.702 -67.367  1.00 48.42  ? 474 TYR C C     1 
ATOM   11870 O  O     . TYR C 1 474 ? -13.561 -9.956  -67.399  1.00 49.48  ? 474 TYR C O     1 
ATOM   11871 C  CB    . TYR C 1 474 ? -15.332 -10.030 -69.684  1.00 52.71  ? 474 TYR C CB    1 
ATOM   11872 C  CG    . TYR C 1 474 ? -15.872 -10.526 -71.000  1.00 53.54  ? 474 TYR C CG    1 
ATOM   11873 C  CD1   . TYR C 1 474 ? -15.134 -11.405 -71.772  1.00 56.45  ? 474 TYR C CD1   1 
ATOM   11874 C  CD2   . TYR C 1 474 ? -17.144 -10.200 -71.434  1.00 56.51  ? 474 TYR C CD2   1 
ATOM   11875 C  CE1   . TYR C 1 474 ? -15.632 -11.919 -72.960  1.00 60.25  ? 474 TYR C CE1   1 
ATOM   11876 C  CE2   . TYR C 1 474 ? -17.664 -10.713 -72.611  1.00 60.87  ? 474 TYR C CE2   1 
ATOM   11877 C  CZ    . TYR C 1 474 ? -16.908 -11.580 -73.383  1.00 62.34  ? 474 TYR C CZ    1 
ATOM   11878 O  OH    . TYR C 1 474 ? -17.410 -12.098 -74.573  1.00 61.58  ? 474 TYR C OH    1 
ATOM   11879 N  N     . MET C 1 475 ? -14.994 -11.188 -66.217  1.00 47.95  ? 475 MET C N     1 
ATOM   11880 C  CA    . MET C 1 475 ? -14.667 -10.534 -64.960  1.00 47.95  ? 475 MET C CA    1 
ATOM   11881 C  C     . MET C 1 475 ? -13.213 -10.812 -64.612  1.00 51.30  ? 475 MET C C     1 
ATOM   11882 O  O     . MET C 1 475 ? -12.503 -9.914  -64.136  1.00 44.28  ? 475 MET C O     1 
ATOM   11883 C  CB    . MET C 1 475 ? -15.596 -10.976 -63.819  1.00 42.90  ? 475 MET C CB    1 
ATOM   11884 C  CG    . MET C 1 475 ? -16.892 -10.181 -63.813  1.00 41.78  ? 475 MET C CG    1 
ATOM   11885 S  SD    . MET C 1 475 ? -18.167 -10.687 -62.610  1.00 42.54  ? 475 MET C SD    1 
ATOM   11886 C  CE    . MET C 1 475 ? -19.466 -9.610  -63.213  1.00 48.00  ? 475 MET C CE    1 
ATOM   11887 N  N     . ASP C 1 476 ? -12.796 -12.063 -64.855  1.00 50.74  ? 476 ASP C N     1 
ATOM   11888 C  CA    . ASP C 1 476 ? -11.408 -12.452 -64.680  1.00 47.48  ? 476 ASP C CA    1 
ATOM   11889 C  C     . ASP C 1 476 ? -10.517 -11.619 -65.589  1.00 46.67  ? 476 ASP C C     1 
ATOM   11890 O  O     . ASP C 1 476 ? -9.444  -11.208 -65.157  1.00 51.41  ? 476 ASP C O     1 
ATOM   11891 C  CB    . ASP C 1 476 ? -11.176 -13.933 -64.972  1.00 53.31  ? 476 ASP C CB    1 
ATOM   11892 C  CG    . ASP C 1 476 ? -11.518 -14.841 -63.806  1.00 59.50  ? 476 ASP C CG    1 
ATOM   11893 O  OD1   . ASP C 1 476 ? -11.907 -14.318 -62.731  1.00 52.48  ? 476 ASP C OD1   1 
ATOM   11894 O  OD2   . ASP C 1 476 ? -11.374 -16.073 -63.973  1.00 66.04  ? 476 ASP C OD2   1 
ATOM   11895 N  N     . ARG C 1 477 ? -10.978 -11.360 -66.821  1.00 49.84  ? 477 ARG C N     1 
ATOM   11896 C  CA    . ARG C 1 477 ? -10.137 -10.703 -67.804  1.00 51.06  ? 477 ARG C CA    1 
ATOM   11897 C  C     . ARG C 1 477 ? -9.939  -9.239  -67.407  1.00 46.89  ? 477 ARG C C     1 
ATOM   11898 O  O     . ARG C 1 477 ? -8.814  -8.767  -67.452  1.00 43.32  ? 477 ARG C O     1 
ATOM   11899 C  CB    . ARG C 1 477 ? -10.637 -10.831 -69.250  1.00 52.65  ? 477 ARG C CB    1 
ATOM   11900 C  CG    . ARG C 1 477 ? -9.553  -10.455 -70.261  1.00 54.28  ? 477 ARG C CG    1 
ATOM   11901 C  CD    . ARG C 1 477 ? -9.967  -10.255 -71.704  1.00 63.25  ? 477 ARG C CD    1 
ATOM   11902 N  NE    . ARG C 1 477 ? -10.067 -11.543 -72.356  1.00 72.82  ? 477 ARG C NE    1 
ATOM   11903 C  CZ    . ARG C 1 477 ? -9.101  -12.129 -73.044  1.00 64.77  ? 477 ARG C CZ    1 
ATOM   11904 N  NH1   . ARG C 1 477 ? -8.090  -11.425 -73.515  1.00 70.14  ? 477 ARG C NH1   1 
ATOM   11905 N  NH2   . ARG C 1 477 ? -9.186  -13.423 -73.292  1.00 66.31  ? 477 ARG C NH2   1 
ATOM   11906 N  N     . ILE C 1 478 ? -11.009 -8.527  -67.025  1.00 44.43  ? 478 ILE C N     1 
ATOM   11907 C  CA    . ILE C 1 478 ? -10.868 -7.141  -66.608  1.00 45.27  ? 478 ILE C CA    1 
ATOM   11908 C  C     . ILE C 1 478 ? -10.026 -7.062  -65.332  1.00 46.39  ? 478 ILE C C     1 
ATOM   11909 O  O     . ILE C 1 478 ? -9.124  -6.230  -65.236  1.00 44.05  ? 478 ILE C O     1 
ATOM   11910 C  CB    . ILE C 1 478 ? -12.222 -6.458  -66.394  1.00 45.67  ? 478 ILE C CB    1 
ATOM   11911 C  CG1   . ILE C 1 478 ? -13.124 -6.567  -67.618  1.00 52.84  ? 478 ILE C CG1   1 
ATOM   11912 C  CG2   . ILE C 1 478 ? -12.017 -5.008  -65.981  1.00 44.47  ? 478 ILE C CG2   1 
ATOM   11913 C  CD1   . ILE C 1 478 ? -12.518 -6.030  -68.873  1.00 53.32  ? 478 ILE C CD1   1 
ATOM   11914 N  N     . ALA C 1 479 ? -10.297 -7.931  -64.350  1.00 44.38  ? 479 ALA C N     1 
ATOM   11915 C  CA    . ALA C 1 479 ? -9.503  -7.915  -63.128  1.00 49.49  ? 479 ALA C CA    1 
ATOM   11916 C  C     . ALA C 1 479 ? -8.010  -7.964  -63.474  1.00 50.84  ? 479 ALA C C     1 
ATOM   11917 O  O     . ALA C 1 479 ? -7.221  -7.163  -62.959  1.00 47.47  ? 479 ALA C O     1 
ATOM   11918 C  CB    . ALA C 1 479 ? -9.902  -9.042  -62.201  1.00 49.06  ? 479 ALA C CB    1 
ATOM   11919 N  N     . LYS C 1 480 ? -7.646  -8.878  -64.386  1.00 45.21  ? 480 LYS C N     1 
ATOM   11920 C  CA    . LYS C 1 480 ? -6.255  -9.110  -64.763  1.00 47.54  ? 480 LYS C CA    1 
ATOM   11921 C  C     . LYS C 1 480 ? -5.603  -7.874  -65.390  1.00 44.48  ? 480 LYS C C     1 
ATOM   11922 O  O     . LYS C 1 480 ? -4.383  -7.754  -65.376  1.00 43.07  ? 480 LYS C O     1 
ATOM   11923 C  CB    . LYS C 1 480 ? -6.149  -10.278 -65.746  1.00 48.40  ? 480 LYS C CB    1 
ATOM   11924 C  CG    . LYS C 1 480 ? -6.157  -11.653 -65.097  1.00 57.28  ? 480 LYS C CG    1 
ATOM   11925 C  CD    . LYS C 1 480 ? -6.213  -12.775 -66.120  1.00 69.85  ? 480 LYS C CD    1 
ATOM   11926 C  CE    . LYS C 1 480 ? -6.465  -14.128 -65.492  1.00 78.45  ? 480 LYS C CE    1 
ATOM   11927 N  NZ    . LYS C 1 480 ? -5.544  -14.363 -64.353  1.00 77.75  ? 480 LYS C NZ    1 
ATOM   11928 N  N     . THR C 1 481 ? -6.383  -6.969  -65.973  1.00 47.26  ? 481 THR C N     1 
ATOM   11929 C  CA    . THR C 1 481 ? -5.789  -5.752  -66.515  1.00 48.92  ? 481 THR C CA    1 
ATOM   11930 C  C     . THR C 1 481 ? -5.324  -4.790  -65.422  1.00 46.44  ? 481 THR C C     1 
ATOM   11931 O  O     . THR C 1 481 ? -4.430  -4.002  -65.687  1.00 50.32  ? 481 THR C O     1 
ATOM   11932 C  CB    . THR C 1 481 ? -6.724  -5.003  -67.463  1.00 44.14  ? 481 THR C CB    1 
ATOM   11933 O  OG1   . THR C 1 481 ? -7.837  -4.517  -66.707  1.00 43.44  ? 481 THR C OG1   1 
ATOM   11934 C  CG2   . THR C 1 481 ? -7.158  -5.869  -68.619  1.00 44.55  ? 481 THR C CG2   1 
ATOM   11935 N  N     . TYR C 1 482 ? -5.893  -4.866  -64.211  1.00 45.57  ? 482 TYR C N     1 
ATOM   11936 C  CA    . TYR C 1 482 ? -5.574  -3.941  -63.127  1.00 42.80  ? 482 TYR C CA    1 
ATOM   11937 C  C     . TYR C 1 482 ? -4.364  -4.456  -62.356  1.00 45.79  ? 482 TYR C C     1 
ATOM   11938 O  O     . TYR C 1 482 ? -4.401  -4.563  -61.135  1.00 45.05  ? 482 TYR C O     1 
ATOM   11939 C  CB    . TYR C 1 482 ? -6.805  -3.726  -62.238  1.00 39.40  ? 482 TYR C CB    1 
ATOM   11940 C  CG    . TYR C 1 482 ? -7.830  -2.834  -62.886  1.00 39.30  ? 482 TYR C CG    1 
ATOM   11941 C  CD1   . TYR C 1 482 ? -7.716  -1.457  -62.831  1.00 40.72  ? 482 TYR C CD1   1 
ATOM   11942 C  CD2   . TYR C 1 482 ? -8.871  -3.364  -63.626  1.00 39.37  ? 482 TYR C CD2   1 
ATOM   11943 C  CE1   . TYR C 1 482 ? -8.641  -0.622  -63.436  1.00 38.49  ? 482 TYR C CE1   1 
ATOM   11944 C  CE2   . TYR C 1 482 ? -9.809  -2.548  -64.227  1.00 38.97  ? 482 TYR C CE2   1 
ATOM   11945 C  CZ    . TYR C 1 482 ? -9.696  -1.168  -64.134  1.00 39.17  ? 482 TYR C CZ    1 
ATOM   11946 O  OH    . TYR C 1 482 ? -10.599 -0.353  -64.773  1.00 38.31  ? 482 TYR C OH    1 
ATOM   11947 N  N     . SER C 1 483 ? -3.259  -4.639  -63.094  1.00 44.20  ? 483 SER C N     1 
ATOM   11948 C  CA    . SER C 1 483 ? -2.176  -5.542  -62.740  1.00 49.65  ? 483 SER C CA    1 
ATOM   11949 C  C     . SER C 1 483 ? -1.039  -4.842  -62.006  1.00 44.63  ? 483 SER C C     1 
ATOM   11950 O  O     . SER C 1 483 ? -0.056  -5.494  -61.684  1.00 45.82  ? 483 SER C O     1 
ATOM   11951 C  CB    . SER C 1 483 ? -1.621  -6.211  -63.992  1.00 47.47  ? 483 SER C CB    1 
ATOM   11952 O  OG    . SER C 1 483 ? -1.157  -5.223  -64.913  1.00 47.07  ? 483 SER C OG    1 
ATOM   11953 N  N     . TRP C 1 484 ? -1.155  -3.540  -61.731  1.00 48.91  ? 484 TRP C N     1 
ATOM   11954 C  CA    . TRP C 1 484 ? -0.038  -2.782  -61.181  1.00 50.25  ? 484 TRP C CA    1 
ATOM   11955 C  C     . TRP C 1 484 ? 0.587   -3.492  -59.984  1.00 47.62  ? 484 TRP C C     1 
ATOM   11956 O  O     . TRP C 1 484 ? -0.100  -3.965  -59.082  1.00 43.78  ? 484 TRP C O     1 
ATOM   11957 C  CB    . TRP C 1 484 ? -0.451  -1.355  -60.784  1.00 51.52  ? 484 TRP C CB    1 
ATOM   11958 C  CG    . TRP C 1 484 ? 0.714   -0.508  -60.358  1.00 50.09  ? 484 TRP C CG    1 
ATOM   11959 C  CD1   . TRP C 1 484 ? 1.593   0.135   -61.176  1.00 48.01  ? 484 TRP C CD1   1 
ATOM   11960 C  CD2   . TRP C 1 484 ? 1.133   -0.214  -59.013  1.00 46.39  ? 484 TRP C CD2   1 
ATOM   11961 N  NE1   . TRP C 1 484 ? 2.511   0.825   -60.436  1.00 48.86  ? 484 TRP C NE1   1 
ATOM   11962 C  CE2   . TRP C 1 484 ? 2.270   0.617   -59.109  1.00 49.55  ? 484 TRP C CE2   1 
ATOM   11963 C  CE3   . TRP C 1 484 ? 0.659   -0.559  -57.745  1.00 46.63  ? 484 TRP C CE3   1 
ATOM   11964 C  CZ2   . TRP C 1 484 ? 2.938   1.110   -57.990  1.00 44.42  ? 484 TRP C CZ2   1 
ATOM   11965 C  CZ3   . TRP C 1 484 ? 1.332   -0.100  -56.633  1.00 49.93  ? 484 TRP C CZ3   1 
ATOM   11966 C  CH2   . TRP C 1 484 ? 2.450   0.737   -56.757  1.00 49.07  ? 484 TRP C CH2   1 
ATOM   11967 N  N     . ASN C 1 485 ? 1.920   -3.472  -59.950  1.00 44.89  ? 485 ASN C N     1 
ATOM   11968 C  CA    . ASN C 1 485 ? 2.698   -4.060  -58.871  1.00 43.44  ? 485 ASN C CA    1 
ATOM   11969 C  C     . ASN C 1 485 ? 2.312   -5.527  -58.679  1.00 47.91  ? 485 ASN C C     1 
ATOM   11970 O  O     . ASN C 1 485 ? 1.936   -5.949  -57.586  1.00 45.55  ? 485 ASN C O     1 
ATOM   11971 C  CB    . ASN C 1 485 ? 2.556   -3.303  -57.556  1.00 43.38  ? 485 ASN C CB    1 
ATOM   11972 C  CG    . ASN C 1 485 ? 3.585   -3.778  -56.559  1.00 46.42  ? 485 ASN C CG    1 
ATOM   11973 O  OD1   . ASN C 1 485 ? 4.587   -4.368  -56.950  1.00 46.18  ? 485 ASN C OD1   1 
ATOM   11974 N  ND2   . ASN C 1 485 ? 3.381   -3.507  -55.290  1.00 48.14  ? 485 ASN C ND2   1 
ATOM   11975 N  N     . ASP C 1 486 ? 2.422   -6.291  -59.767  1.00 47.83  ? 486 ASP C N     1 
ATOM   11976 C  CA    . ASP C 1 486 ? 2.158   -7.724  -59.776  1.00 49.30  ? 486 ASP C CA    1 
ATOM   11977 C  C     . ASP C 1 486 ? 0.794   -8.002  -59.156  1.00 44.68  ? 486 ASP C C     1 
ATOM   11978 O  O     . ASP C 1 486 ? 0.683   -8.872  -58.300  1.00 43.03  ? 486 ASP C O     1 
ATOM   11979 C  CB    . ASP C 1 486 ? 3.221   -8.541  -59.036  1.00 48.68  ? 486 ASP C CB    1 
ATOM   11980 C  CG    . ASP C 1 486 ? 3.112   -10.046 -59.300  1.00 53.54  ? 486 ASP C CG    1 
ATOM   11981 O  OD1   . ASP C 1 486 ? 2.844   -10.420 -60.442  1.00 51.43  ? 486 ASP C OD1   1 
ATOM   11982 O  OD2   . ASP C 1 486 ? 3.325   -10.834 -58.372  1.00 54.94  ? 486 ASP C OD2   1 
ATOM   11983 N  N     . ASN C 1 487 ? -0.231  -7.276  -59.621  1.00 45.95  ? 487 ASN C N     1 
ATOM   11984 C  CA    . ASN C 1 487 ? -1.607  -7.510  -59.198  1.00 49.15  ? 487 ASN C CA    1 
ATOM   11985 C  C     . ASN C 1 487 ? -1.738  -7.274  -57.689  1.00 47.22  ? 487 ASN C C     1 
ATOM   11986 O  O     . ASN C 1 487 ? -2.387  -8.040  -56.976  1.00 47.62  ? 487 ASN C O     1 
ATOM   11987 C  CB    . ASN C 1 487 ? -2.080  -8.917  -59.571  1.00 46.80  ? 487 ASN C CB    1 
ATOM   11988 C  CG    . ASN C 1 487 ? -1.995  -9.198  -61.057  1.00 49.16  ? 487 ASN C CG    1 
ATOM   11989 O  OD1   . ASN C 1 487 ? -1.157  -9.976  -61.494  1.00 52.50  ? 487 ASN C OD1   1 
ATOM   11990 N  ND2   . ASN C 1 487 ? -2.868  -8.600  -61.842  1.00 50.87  ? 487 ASN C ND2   1 
ATOM   11991 N  N     . ALA C 1 488 ? -1.122  -6.196  -57.201  1.00 45.75  ? 488 ALA C N     1 
ATOM   11992 C  CA    . ALA C 1 488 ? -1.095  -5.925  -55.772  1.00 40.90  ? 488 ALA C CA    1 
ATOM   11993 C  C     . ALA C 1 488 ? -2.530  -5.692  -55.267  1.00 38.92  ? 488 ALA C C     1 
ATOM   11994 O  O     . ALA C 1 488 ? -2.910  -6.188  -54.201  1.00 37.62  ? 488 ALA C O     1 
ATOM   11995 C  CB    . ALA C 1 488 ? -0.195  -4.750  -55.510  1.00 39.40  ? 488 ALA C CB    1 
ATOM   11996 N  N     . LEU C 1 489 ? -3.358  -5.001  -56.061  1.00 38.44  ? 489 LEU C N     1 
ATOM   11997 C  CA    . LEU C 1 489 ? -4.700  -4.682  -55.593  1.00 37.75  ? 489 LEU C CA    1 
ATOM   11998 C  C     . LEU C 1 489 ? -5.559  -5.940  -55.445  1.00 38.57  ? 489 LEU C C     1 
ATOM   11999 O  O     . LEU C 1 489 ? -6.294  -6.065  -54.471  1.00 44.42  ? 489 LEU C O     1 
ATOM   12000 C  CB    . LEU C 1 489 ? -5.370  -3.660  -56.507  1.00 36.54  ? 489 LEU C CB    1 
ATOM   12001 C  CG    . LEU C 1 489 ? -6.794  -3.273  -56.082  1.00 42.32  ? 489 LEU C CG    1 
ATOM   12002 C  CD1   . LEU C 1 489 ? -6.813  -2.721  -54.663  1.00 43.29  ? 489 LEU C CD1   1 
ATOM   12003 C  CD2   . LEU C 1 489 ? -7.394  -2.269  -57.049  1.00 41.20  ? 489 LEU C CD2   1 
ATOM   12004 N  N     . TRP C 1 490 ? -5.511  -6.862  -56.411  1.00 44.86  ? 490 TRP C N     1 
ATOM   12005 C  CA    . TRP C 1 490 ? -6.321  -8.078  -56.347  1.00 42.50  ? 490 TRP C CA    1 
ATOM   12006 C  C     . TRP C 1 490 ? -5.796  -9.041  -55.278  1.00 38.80  ? 490 TRP C C     1 
ATOM   12007 O  O     . TRP C 1 490 ? -6.553  -9.801  -54.681  1.00 41.34  ? 490 TRP C O     1 
ATOM   12008 C  CB    . TRP C 1 490 ? -6.529  -8.726  -57.736  1.00 38.56  ? 490 TRP C CB    1 
ATOM   12009 C  CG    . TRP C 1 490 ? -7.926  -8.505  -58.252  1.00 39.81  ? 490 TRP C CG    1 
ATOM   12010 C  CD1   . TRP C 1 490 ? -8.938  -9.425  -58.314  1.00 39.61  ? 490 TRP C CD1   1 
ATOM   12011 C  CD2   . TRP C 1 490 ? -8.515  -7.254  -58.652  1.00 42.78  ? 490 TRP C CD2   1 
ATOM   12012 N  NE1   . TRP C 1 490 ? -10.106 -8.844  -58.736  1.00 41.28  ? 490 TRP C NE1   1 
ATOM   12013 C  CE2   . TRP C 1 490 ? -9.869  -7.513  -58.966  1.00 41.04  ? 490 TRP C CE2   1 
ATOM   12014 C  CE3   . TRP C 1 490 ? -8.029  -5.949  -58.781  1.00 42.68  ? 490 TRP C CE3   1 
ATOM   12015 C  CZ2   . TRP C 1 490 ? -10.718 -6.516  -59.437  1.00 45.49  ? 490 TRP C CZ2   1 
ATOM   12016 C  CZ3   . TRP C 1 490 ? -8.874  -4.962  -59.240  1.00 41.08  ? 490 TRP C CZ3   1 
ATOM   12017 C  CH2   . TRP C 1 490 ? -10.194 -5.248  -59.575  1.00 46.62  ? 490 TRP C CH2   1 
ATOM   12018 N  N     . LYS C 1 491 ? -4.519  -8.949  -54.934  1.00 41.78  ? 491 LYS C N     1 
ATOM   12019 C  CA    . LYS C 1 491 ? -4.002  -9.712  -53.808  1.00 43.61  ? 491 LYS C CA    1 
ATOM   12020 C  C     . LYS C 1 491 ? -4.588  -9.216  -52.489  1.00 44.87  ? 491 LYS C C     1 
ATOM   12021 O  O     . LYS C 1 491 ? -4.784  -10.002 -51.565  1.00 41.85  ? 491 LYS C O     1 
ATOM   12022 C  CB    . LYS C 1 491 ? -2.476  -9.633  -53.774  1.00 43.50  ? 491 LYS C CB    1 
ATOM   12023 C  CG    . LYS C 1 491 ? -1.832  -10.457 -54.874  1.00 45.84  ? 491 LYS C CG    1 
ATOM   12024 C  CD    . LYS C 1 491 ? -0.340  -10.287 -54.987  1.00 52.17  ? 491 LYS C CD    1 
ATOM   12025 C  CE    . LYS C 1 491 ? 0.183   -11.094 -56.155  1.00 55.22  ? 491 LYS C CE    1 
ATOM   12026 N  NZ    . LYS C 1 491 ? 1.619   -10.835 -56.391  1.00 58.24  ? 491 LYS C NZ    1 
ATOM   12027 N  N     . MET C 1 492 ? -4.811  -7.902  -52.375  1.00 41.82  ? 492 MET C N     1 
ATOM   12028 C  CA    . MET C 1 492 ? -5.433  -7.372  -51.178  1.00 41.86  ? 492 MET C CA    1 
ATOM   12029 C  C     . MET C 1 492 ? -6.899  -7.804  -51.141  1.00 41.45  ? 492 MET C C     1 
ATOM   12030 O  O     . MET C 1 492 ? -7.390  -8.204  -50.090  1.00 42.60  ? 492 MET C O     1 
ATOM   12031 C  CB    . MET C 1 492 ? -5.342  -5.847  -51.114  1.00 38.96  ? 492 MET C CB    1 
ATOM   12032 C  CG    . MET C 1 492 ? -5.797  -5.310  -49.795  1.00 38.18  ? 492 MET C CG    1 
ATOM   12033 S  SD    . MET C 1 492 ? -5.808  -3.532  -49.829  1.00 48.88  ? 492 MET C SD    1 
ATOM   12034 C  CE    . MET C 1 492 ? -7.337  -3.220  -50.713  1.00 50.36  ? 492 MET C CE    1 
ATOM   12035 N  N     . HIS C 1 493 ? -7.594  -7.734  -52.284  1.00 44.10  ? 493 HIS C N     1 
ATOM   12036 C  CA    . HIS C 1 493 ? -8.981  -8.168  -52.341  1.00 43.76  ? 493 HIS C CA    1 
ATOM   12037 C  C     . HIS C 1 493 ? -9.112  -9.633  -51.926  1.00 47.21  ? 493 HIS C C     1 
ATOM   12038 O  O     . HIS C 1 493 ? -10.066 -9.976  -51.231  1.00 47.57  ? 493 HIS C O     1 
ATOM   12039 C  CB    . HIS C 1 493 ? -9.625  -7.983  -53.719  1.00 44.54  ? 493 HIS C CB    1 
ATOM   12040 C  CG    . HIS C 1 493 ? -9.804  -6.571  -54.157  1.00 46.32  ? 493 HIS C CG    1 
ATOM   12041 N  ND1   . HIS C 1 493 ? -10.046 -5.511  -53.304  1.00 40.59  ? 493 HIS C ND1   1 
ATOM   12042 C  CD2   . HIS C 1 493 ? -9.726  -6.061  -55.391  1.00 38.39  ? 493 HIS C CD2   1 
ATOM   12043 C  CE1   . HIS C 1 493 ? -10.149 -4.405  -54.027  1.00 46.48  ? 493 HIS C CE1   1 
ATOM   12044 N  NE2   . HIS C 1 493 ? -9.972  -4.715  -55.302  1.00 39.52  ? 493 HIS C NE2   1 
ATOM   12045 N  N     . GLU C 1 494 ? -8.171  -10.490 -52.351  1.00 44.94  ? 494 GLU C N     1 
ATOM   12046 C  CA    . GLU C 1 494 ? -8.252  -11.909 -52.033  1.00 48.29  ? 494 GLU C CA    1 
ATOM   12047 C  C     . GLU C 1 494 ? -8.031  -12.091 -50.533  1.00 44.07  ? 494 GLU C C     1 
ATOM   12048 O  O     . GLU C 1 494 ? -8.538  -13.049 -49.963  1.00 46.11  ? 494 GLU C O     1 
ATOM   12049 C  CB    . GLU C 1 494 ? -7.242  -12.752 -52.833  1.00 45.75  ? 494 GLU C CB    1 
ATOM   12050 C  CG    . GLU C 1 494 ? -7.585  -12.972 -54.318  1.00 48.81  ? 494 GLU C CG    1 
ATOM   12051 C  CD    . GLU C 1 494 ? -8.726  -13.923 -54.668  1.00 52.49  ? 494 GLU C CD    1 
ATOM   12052 O  OE1   . GLU C 1 494 ? -9.228  -14.646 -53.777  1.00 57.63  ? 494 GLU C OE1   1 
ATOM   12053 O  OE2   . GLU C 1 494 ? -9.124  -13.940 -55.842  1.00 55.28  ? 494 GLU C OE2   1 
ATOM   12054 N  N     . THR C 1 495 ? -7.226  -11.200 -49.920  1.00 45.45  ? 495 THR C N     1 
ATOM   12055 C  CA    . THR C 1 495 ? -6.906  -11.288 -48.503  1.00 46.09  ? 495 THR C CA    1 
ATOM   12056 C  C     . THR C 1 495 ? -8.141  -10.953 -47.668  1.00 45.61  ? 495 THR C C     1 
ATOM   12057 O  O     . THR C 1 495 ? -8.435  -11.609 -46.671  1.00 50.55  ? 495 THR C O     1 
ATOM   12058 C  CB    . THR C 1 495 ? -5.740  -10.370 -48.126  1.00 49.50  ? 495 THR C CB    1 
ATOM   12059 O  OG1   . THR C 1 495 ? -4.583  -10.872 -48.794  1.00 47.75  ? 495 THR C OG1   1 
ATOM   12060 C  CG2   . THR C 1 495 ? -5.478  -10.301 -46.633  1.00 48.26  ? 495 THR C CG2   1 
ATOM   12061 N  N     . ILE C 1 496 ? -8.872  -9.929  -48.096  1.00 44.58  ? 496 ILE C N     1 
ATOM   12062 C  CA    . ILE C 1 496 ? -10.075 -9.536  -47.396  1.00 44.91  ? 496 ILE C CA    1 
ATOM   12063 C  C     . ILE C 1 496 ? -11.126 -10.613 -47.604  1.00 42.38  ? 496 ILE C C     1 
ATOM   12064 O  O     . ILE C 1 496 ? -11.865 -10.946 -46.673  1.00 45.71  ? 496 ILE C O     1 
ATOM   12065 C  CB    . ILE C 1 496 ? -10.549 -8.139  -47.846  1.00 40.20  ? 496 ILE C CB    1 
ATOM   12066 C  CG1   . ILE C 1 496 ? -9.582  -7.058  -47.365  1.00 40.98  ? 496 ILE C CG1   1 
ATOM   12067 C  CG2   . ILE C 1 496 ? -11.960 -7.885  -47.362  1.00 39.99  ? 496 ILE C CG2   1 
ATOM   12068 C  CD1   . ILE C 1 496 ? -9.711  -5.751  -48.080  1.00 46.04  ? 496 ILE C CD1   1 
ATOM   12069 N  N     . LYS C 1 497 ? -11.177 -11.140 -48.830  1.00 44.57  ? 497 LYS C N     1 
ATOM   12070 C  CA    . LYS C 1 497 ? -12.139 -12.170 -49.208  1.00 46.30  ? 497 LYS C CA    1 
ATOM   12071 C  C     . LYS C 1 497 ? -12.016 -13.383 -48.293  1.00 40.62  ? 497 LYS C C     1 
ATOM   12072 O  O     . LYS C 1 497 ? -13.015 -13.968 -47.884  1.00 42.52  ? 497 LYS C O     1 
ATOM   12073 C  CB    . LYS C 1 497 ? -11.921 -12.594 -50.660  1.00 48.51  ? 497 LYS C CB    1 
ATOM   12074 C  CG    . LYS C 1 497 ? -12.770 -13.761 -51.155  1.00 48.20  ? 497 LYS C CG    1 
ATOM   12075 C  CD    . LYS C 1 497 ? -14.247 -13.504 -51.085  1.00 45.80  ? 497 LYS C CD    1 
ATOM   12076 C  CE    . LYS C 1 497 ? -15.031 -14.573 -51.802  1.00 44.59  ? 497 LYS C CE    1 
ATOM   12077 N  NZ    . LYS C 1 497 ? -16.486 -14.377 -51.625  1.00 47.08  ? 497 LYS C NZ    1 
ATOM   12078 N  N     . ASP C 1 498 ? -10.773 -13.771 -48.029  1.00 42.03  ? 498 ASP C N     1 
ATOM   12079 C  CA    . ASP C 1 498 ? -10.484 -14.970 -47.266  1.00 48.13  ? 498 ASP C CA    1 
ATOM   12080 C  C     . ASP C 1 498 ? -10.775 -14.721 -45.786  1.00 47.55  ? 498 ASP C C     1 
ATOM   12081 O  O     . ASP C 1 498 ? -11.041 -15.664 -45.046  1.00 50.57  ? 498 ASP C O     1 
ATOM   12082 C  CB    . ASP C 1 498 ? -9.013  -15.384 -47.407  1.00 52.73  ? 498 ASP C CB    1 
ATOM   12083 C  CG    . ASP C 1 498 ? -8.628  -16.086 -48.698  1.00 53.33  ? 498 ASP C CG    1 
ATOM   12084 O  OD1   . ASP C 1 498 ? -9.528  -16.498 -49.446  1.00 47.54  ? 498 ASP C OD1   1 
ATOM   12085 O  OD2   . ASP C 1 498 ? -7.407  -16.211 -48.940  1.00 54.91  ? 498 ASP C OD2   1 
ATOM   12086 N  N     . ALA C 1 499 ? -10.633 -13.466 -45.338  1.00 44.18  ? 499 ALA C N     1 
ATOM   12087 C  CA    . ALA C 1 499 ? -10.822 -13.159 -43.928  1.00 47.15  ? 499 ALA C CA    1 
ATOM   12088 C  C     . ALA C 1 499 ? -12.315 -13.074 -43.630  1.00 42.98  ? 499 ALA C C     1 
ATOM   12089 O  O     . ALA C 1 499 ? -12.742 -13.517 -42.574  1.00 47.78  ? 499 ALA C O     1 
ATOM   12090 C  CB    . ALA C 1 499 ? -10.086 -11.903 -43.547  1.00 50.33  ? 499 ALA C CB    1 
ATOM   12091 N  N     . LEU C 1 500 ? -13.106 -12.599 -44.600  1.00 43.40  ? 500 LEU C N     1 
ATOM   12092 C  CA    . LEU C 1 500 ? -14.545 -12.438 -44.423  1.00 41.28  ? 500 LEU C CA    1 
ATOM   12093 C  C     . LEU C 1 500 ? -15.316 -13.669 -44.875  1.00 44.43  ? 500 LEU C C     1 
ATOM   12094 O  O     . LEU C 1 500 ? -16.472 -13.835 -44.479  1.00 46.74  ? 500 LEU C O     1 
ATOM   12095 C  CB    . LEU C 1 500 ? -15.039 -11.260 -45.267  1.00 38.70  ? 500 LEU C CB    1 
ATOM   12096 C  CG    . LEU C 1 500 ? -14.571 -9.887  -44.812  1.00 41.69  ? 500 LEU C CG    1 
ATOM   12097 C  CD1   . LEU C 1 500 ? -15.113 -8.805  -45.752  1.00 43.48  ? 500 LEU C CD1   1 
ATOM   12098 C  CD2   . LEU C 1 500 ? -14.989 -9.658  -43.371  1.00 43.33  ? 500 LEU C CD2   1 
ATOM   12099 N  N     . ASP C 1 501 ? -14.742 -14.430 -45.810  1.00 46.01  ? 501 ASP C N     1 
ATOM   12100 C  CA    . ASP C 1 501 ? -15.438 -15.563 -46.400  1.00 47.26  ? 501 ASP C CA    1 
ATOM   12101 C  C     . ASP C 1 501 ? -14.450 -16.716 -46.500  1.00 51.87  ? 501 ASP C C     1 
ATOM   12102 O  O     . ASP C 1 501 ? -14.072 -17.135 -47.589  1.00 52.60  ? 501 ASP C O     1 
ATOM   12103 C  CB    . ASP C 1 501 ? -16.029 -15.190 -47.759  1.00 46.64  ? 501 ASP C CB    1 
ATOM   12104 C  CG    . ASP C 1 501 ? -16.942 -16.235 -48.380  1.00 46.81  ? 501 ASP C CG    1 
ATOM   12105 O  OD1   . ASP C 1 501 ? -17.224 -17.276 -47.714  1.00 53.88  ? 501 ASP C OD1   1 
ATOM   12106 O  OD2   . ASP C 1 501 ? -17.338 -16.023 -49.537  1.00 44.09  ? 501 ASP C OD2   1 
ATOM   12107 N  N     . PRO C 1 502 ? -14.003 -17.268 -45.355  1.00 49.59  ? 502 PRO C N     1 
ATOM   12108 C  CA    . PRO C 1 502 ? -12.998 -18.329 -45.378  1.00 54.21  ? 502 PRO C CA    1 
ATOM   12109 C  C     . PRO C 1 502 ? -13.441 -19.506 -46.248  1.00 49.98  ? 502 PRO C C     1 
ATOM   12110 O  O     . PRO C 1 502 ? -12.606 -20.124 -46.904  1.00 47.26  ? 502 PRO C O     1 
ATOM   12111 C  CB    . PRO C 1 502 ? -12.774 -18.710 -43.903  1.00 51.91  ? 502 PRO C CB    1 
ATOM   12112 C  CG    . PRO C 1 502 ? -13.851 -17.963 -43.095  1.00 48.00  ? 502 PRO C CG    1 
ATOM   12113 C  CD    . PRO C 1 502 ? -14.431 -16.899 -44.000  1.00 48.74  ? 502 PRO C CD    1 
ATOM   12114 N  N     . ASN C 1 503 ? -14.748 -19.790 -46.286  1.00 49.06  ? 503 ASN C N     1 
ATOM   12115 C  CA    . ASN C 1 503 ? -15.257 -20.963 -46.992  1.00 52.23  ? 503 ASN C CA    1 
ATOM   12116 C  C     . ASN C 1 503 ? -15.574 -20.657 -48.444  1.00 52.08  ? 503 ASN C C     1 
ATOM   12117 O  O     . ASN C 1 503 ? -15.938 -21.554 -49.194  1.00 56.60  ? 503 ASN C O     1 
ATOM   12118 C  CB    . ASN C 1 503 ? -16.520 -21.514 -46.328  1.00 45.59  ? 503 ASN C CB    1 
ATOM   12119 C  CG    . ASN C 1 503 ? -16.185 -22.045 -44.960  1.00 45.83  ? 503 ASN C CG    1 
ATOM   12120 O  OD1   . ASN C 1 503 ? -15.169 -22.709 -44.805  1.00 50.05  ? 503 ASN C OD1   1 
ATOM   12121 N  ND2   . ASN C 1 503 ? -16.963 -21.677 -43.960  1.00 49.63  ? 503 ASN C ND2   1 
ATOM   12122 N  N     . GLY C 1 504 ? -15.525 -19.372 -48.797  1.00 54.92  ? 504 GLY C N     1 
ATOM   12123 C  CA    . GLY C 1 504 ? -15.686 -18.948 -50.170  1.00 46.39  ? 504 GLY C CA    1 
ATOM   12124 C  C     . GLY C 1 504 ? -17.063 -19.284 -50.720  1.00 48.41  ? 504 GLY C C     1 
ATOM   12125 O  O     . GLY C 1 504 ? -17.151 -19.776 -51.833  1.00 57.55  ? 504 GLY C O     1 
ATOM   12126 N  N     . ILE C 1 505 ? -18.139 -18.947 -50.004  1.00 45.52  ? 505 ILE C N     1 
ATOM   12127 C  CA    . ILE C 1 505 ? -19.474 -19.305 -50.477  1.00 45.09  ? 505 ILE C CA    1 
ATOM   12128 C  C     . ILE C 1 505 ? -20.219 -18.140 -51.143  1.00 44.50  ? 505 ILE C C     1 
ATOM   12129 O  O     . ILE C 1 505 ? -21.264 -18.348 -51.738  1.00 47.33  ? 505 ILE C O     1 
ATOM   12130 C  CB    . ILE C 1 505 ? -20.290 -19.983 -49.353  1.00 52.07  ? 505 ILE C CB    1 
ATOM   12131 C  CG1   . ILE C 1 505 ? -20.390 -19.141 -48.081  1.00 52.59  ? 505 ILE C CG1   1 
ATOM   12132 C  CG2   . ILE C 1 505 ? -19.727 -21.366 -49.055  1.00 53.71  ? 505 ILE C CG2   1 
ATOM   12133 C  CD1   . ILE C 1 505 ? -21.477 -18.120 -48.145  1.00 57.77  ? 505 ILE C CD1   1 
ATOM   12134 N  N     . LEU C 1 506 ? -19.706 -16.909 -51.110  1.00 43.72  ? 506 LEU C N     1 
ATOM   12135 C  CA    . LEU C 1 506 ? -20.369 -15.828 -51.826  1.00 45.72  ? 506 LEU C CA    1 
ATOM   12136 C  C     . LEU C 1 506 ? -19.717 -15.573 -53.189  1.00 48.58  ? 506 LEU C C     1 
ATOM   12137 O  O     . LEU C 1 506 ? -18.532 -15.251 -53.253  1.00 47.23  ? 506 LEU C O     1 
ATOM   12138 C  CB    . LEU C 1 506 ? -20.291 -14.530 -51.016  1.00 51.14  ? 506 LEU C CB    1 
ATOM   12139 C  CG    . LEU C 1 506 ? -21.288 -14.330 -49.884  1.00 55.85  ? 506 LEU C CG    1 
ATOM   12140 C  CD1   . LEU C 1 506 ? -21.354 -12.845 -49.544  1.00 56.39  ? 506 LEU C CD1   1 
ATOM   12141 C  CD2   . LEU C 1 506 ? -22.669 -14.859 -50.241  1.00 57.56  ? 506 LEU C CD2   1 
ATOM   12142 N  N     . ALA C 1 507 ? -20.545 -15.649 -54.246  1.00 42.09  ? 507 ALA C N     1 
ATOM   12143 C  CA    . ALA C 1 507 ? -20.248 -15.308 -55.630  1.00 48.72  ? 507 ALA C CA    1 
ATOM   12144 C  C     . ALA C 1 507 ? -18.776 -15.530 -55.990  1.00 48.69  ? 507 ALA C C     1 
ATOM   12145 O  O     . ALA C 1 507 ? -18.066 -14.599 -56.363  1.00 46.91  ? 507 ALA C O     1 
ATOM   12146 C  CB    . ALA C 1 507 ? -20.705 -13.891 -55.884  1.00 51.11  ? 507 ALA C CB    1 
ATOM   12147 N  N     . PRO C 1 508 ? -18.273 -16.782 -55.964  1.00 48.67  ? 508 PRO C N     1 
ATOM   12148 C  CA    . PRO C 1 508 ? -16.896 -17.039 -56.374  1.00 45.69  ? 508 PRO C CA    1 
ATOM   12149 C  C     . PRO C 1 508 ? -16.741 -16.550 -57.806  1.00 41.39  ? 508 PRO C C     1 
ATOM   12150 O  O     . PRO C 1 508 ? -17.539 -16.896 -58.661  1.00 43.19  ? 508 PRO C O     1 
ATOM   12151 C  CB    . PRO C 1 508 ? -16.730 -18.566 -56.283  1.00 52.59  ? 508 PRO C CB    1 
ATOM   12152 C  CG    . PRO C 1 508 ? -17.929 -19.061 -55.486  1.00 47.63  ? 508 PRO C CG    1 
ATOM   12153 C  CD    . PRO C 1 508 ? -19.011 -18.013 -55.660  1.00 49.81  ? 508 PRO C CD    1 
ATOM   12154 N  N     . GLY C 1 509 ? -15.755 -15.675 -58.029  1.00 45.03  ? 509 GLY C N     1 
ATOM   12155 C  CA    . GLY C 1 509 ? -15.471 -15.123 -59.336  1.00 43.10  ? 509 GLY C CA    1 
ATOM   12156 C  C     . GLY C 1 509 ? -15.989 -13.702 -59.548  1.00 44.15  ? 509 GLY C C     1 
ATOM   12157 O  O     . GLY C 1 509 ? -15.541 -13.021 -60.462  1.00 44.13  ? 509 GLY C O     1 
ATOM   12158 N  N     . LYS C 1 510 ? -16.931 -13.228 -58.733  1.00 45.37  ? 510 LYS C N     1 
ATOM   12159 C  CA    . LYS C 1 510 ? -17.386 -11.853 -58.882  1.00 43.25  ? 510 LYS C CA    1 
ATOM   12160 C  C     . LYS C 1 510 ? -16.167 -10.924 -58.855  1.00 36.80  ? 510 LYS C C     1 
ATOM   12161 O  O     . LYS C 1 510 ? -15.327 -11.057 -57.983  1.00 36.39  ? 510 LYS C O     1 
ATOM   12162 C  CB    . LYS C 1 510 ? -18.393 -11.506 -57.780  1.00 47.81  ? 510 LYS C CB    1 
ATOM   12163 C  CG    . LYS C 1 510 ? -18.849 -10.060 -57.750  1.00 49.34  ? 510 LYS C CG    1 
ATOM   12164 C  CD    . LYS C 1 510 ? -19.621 -9.604  -58.979  1.00 56.17  ? 510 LYS C CD    1 
ATOM   12165 C  CE    . LYS C 1 510 ? -19.795 -8.094  -58.963  1.00 60.60  ? 510 LYS C CE    1 
ATOM   12166 N  NZ    . LYS C 1 510 ? -20.381 -7.558  -60.212  1.00 56.91  ? 510 LYS C NZ    1 
ATOM   12167 N  N     . SER C 1 511 ? -16.054 -10.045 -59.856  1.00 36.13  ? 511 SER C N     1 
ATOM   12168 C  CA    . SER C 1 511 ? -14.964 -9.088  -59.997  1.00 40.29  ? 511 SER C CA    1 
ATOM   12169 C  C     . SER C 1 511 ? -13.603 -9.781  -60.017  1.00 39.96  ? 511 SER C C     1 
ATOM   12170 O  O     . SER C 1 511 ? -12.584 -9.162  -59.714  1.00 42.09  ? 511 SER C O     1 
ATOM   12171 C  CB    . SER C 1 511 ? -15.007 -8.025  -58.919  1.00 42.10  ? 511 SER C CB    1 
ATOM   12172 O  OG    . SER C 1 511 ? -16.203 -7.273  -58.987  1.00 39.23  ? 511 SER C OG    1 
ATOM   12173 N  N     . GLY C 1 512 ? -13.590 -11.057 -60.419  1.00 39.27  ? 512 GLY C N     1 
ATOM   12174 C  CA    . GLY C 1 512 ? -12.362 -11.826 -60.502  1.00 38.42  ? 512 GLY C CA    1 
ATOM   12175 C  C     . GLY C 1 512 ? -11.796 -12.168 -59.131  1.00 38.22  ? 512 GLY C C     1 
ATOM   12176 O  O     . GLY C 1 512 ? -10.592 -12.375 -58.987  1.00 42.74  ? 512 GLY C O     1 
ATOM   12177 N  N     . ILE C 1 513 ? -12.655 -12.185 -58.107  1.00 42.53  ? 513 ILE C N     1 
ATOM   12178 C  CA    . ILE C 1 513 ? -12.216 -12.516 -56.753  1.00 39.32  ? 513 ILE C CA    1 
ATOM   12179 C  C     . ILE C 1 513 ? -12.736 -13.914 -56.422  1.00 40.41  ? 513 ILE C C     1 
ATOM   12180 O  O     . ILE C 1 513 ? -13.951 -14.128 -56.428  1.00 39.46  ? 513 ILE C O     1 
ATOM   12181 C  CB    . ILE C 1 513 ? -12.721 -11.469 -55.737  1.00 42.75  ? 513 ILE C CB    1 
ATOM   12182 C  CG1   . ILE C 1 513 ? -12.205 -10.055 -56.029  1.00 45.12  ? 513 ILE C CG1   1 
ATOM   12183 C  CG2   . ILE C 1 513 ? -12.400 -11.900 -54.315  1.00 40.83  ? 513 ILE C CG2   1 
ATOM   12184 C  CD1   . ILE C 1 513 ? -12.910 -8.951  -55.236  1.00 43.11  ? 513 ILE C CD1   1 
ATOM   12185 N  N     . TRP C 1 514 ? -11.841 -14.823 -56.030  1.00 44.14  ? 514 TRP C N     1 
ATOM   12186 C  CA    . TRP C 1 514 ? -12.147 -16.248 -56.048  1.00 47.83  ? 514 TRP C CA    1 
ATOM   12187 C  C     . TRP C 1 514 ? -12.213 -16.884 -54.655  1.00 51.56  ? 514 TRP C C     1 
ATOM   12188 O  O     . TRP C 1 514 ? -13.063 -17.752 -54.416  1.00 56.24  ? 514 TRP C O     1 
ATOM   12189 C  CB    . TRP C 1 514 ? -11.171 -16.957 -57.008  1.00 48.82  ? 514 TRP C CB    1 
ATOM   12190 C  CG    . TRP C 1 514 ? -11.634 -16.810 -58.428  1.00 47.54  ? 514 TRP C CG    1 
ATOM   12191 C  CD1   . TRP C 1 514 ? -11.244 -15.883 -59.354  1.00 46.97  ? 514 TRP C CD1   1 
ATOM   12192 C  CD2   . TRP C 1 514 ? -12.666 -17.588 -59.053  1.00 46.90  ? 514 TRP C CD2   1 
ATOM   12193 N  NE1   . TRP C 1 514 ? -11.952 -16.042 -60.517  1.00 44.82  ? 514 TRP C NE1   1 
ATOM   12194 C  CE2   . TRP C 1 514 ? -12.824 -17.087 -60.361  1.00 43.96  ? 514 TRP C CE2   1 
ATOM   12195 C  CE3   . TRP C 1 514 ? -13.440 -18.679 -58.637  1.00 51.42  ? 514 TRP C CE3   1 
ATOM   12196 C  CZ2   . TRP C 1 514 ? -13.737 -17.636 -61.252  1.00 46.54  ? 514 TRP C CZ2   1 
ATOM   12197 C  CZ3   . TRP C 1 514 ? -14.354 -19.210 -59.517  1.00 52.98  ? 514 TRP C CZ3   1 
ATOM   12198 C  CH2   . TRP C 1 514 ? -14.489 -18.700 -60.809  1.00 50.08  ? 514 TRP C CH2   1 
ATOM   12199 N  N     . GLY C 1 515 ? -11.342 -16.479 -53.729  1.00 46.52  ? 515 GLY C N     1 
ATOM   12200 C  CA    . GLY C 1 515 ? -11.243 -17.171 -52.445  1.00 44.30  ? 515 GLY C CA    1 
ATOM   12201 C  C     . GLY C 1 515 ? -10.209 -18.297 -52.472  1.00 42.96  ? 515 GLY C C     1 
ATOM   12202 O  O     . GLY C 1 515 ? -9.983  -18.873 -53.530  1.00 49.49  ? 515 GLY C O     1 
ATOM   12203 N  N     . LYS C 1 516 ? -9.618  -18.630 -51.312  1.00 42.47  ? 516 LYS C N     1 
ATOM   12204 C  CA    . LYS C 1 516 ? -8.496  -19.562 -51.249  1.00 53.69  ? 516 LYS C CA    1 
ATOM   12205 C  C     . LYS C 1 516 ? -8.888  -20.960 -51.737  1.00 52.77  ? 516 LYS C C     1 
ATOM   12206 O  O     . LYS C 1 516 ? -8.032  -21.703 -52.184  1.00 51.67  ? 516 LYS C O     1 
ATOM   12207 C  CB    . LYS C 1 516 ? -7.872  -19.661 -49.851  1.00 51.75  ? 516 LYS C CB    1 
ATOM   12208 C  CG    . LYS C 1 516 ? -8.803  -20.094 -48.723  1.00 58.16  ? 516 LYS C CG    1 
ATOM   12209 C  CD    . LYS C 1 516 ? -8.102  -20.147 -47.370  1.00 61.69  ? 516 LYS C CD    1 
ATOM   12210 C  CE    . LYS C 1 516 ? -9.023  -19.991 -46.176  1.00 68.93  ? 516 LYS C CE    1 
ATOM   12211 N  NZ    . LYS C 1 516 ? -10.039 -21.066 -46.108  1.00 73.01  ? 516 LYS C NZ    1 
ATOM   12212 N  N     . ASN C 1 517 ? -10.172 -21.310 -51.714  1.00 54.05  ? 517 ASN C N     1 
ATOM   12213 C  CA    . ASN C 1 517 ? -10.577 -22.653 -52.102  1.00 59.29  ? 517 ASN C CA    1 
ATOM   12214 C  C     . ASN C 1 517 ? -10.468 -22.845 -53.614  1.00 59.82  ? 517 ASN C C     1 
ATOM   12215 O  O     . ASN C 1 517 ? -10.401 -23.981 -54.067  1.00 68.51  ? 517 ASN C O     1 
ATOM   12216 C  CB    . ASN C 1 517 ? -11.991 -23.000 -51.620  1.00 53.31  ? 517 ASN C CB    1 
ATOM   12217 C  CG    . ASN C 1 517 ? -12.080 -23.057 -50.110  1.00 60.62  ? 517 ASN C CG    1 
ATOM   12218 O  OD1   . ASN C 1 517 ? -11.175 -23.554 -49.447  1.00 65.17  ? 517 ASN C OD1   1 
ATOM   12219 N  ND2   . ASN C 1 517 ? -13.142 -22.508 -49.551  1.00 71.74  ? 517 ASN C ND2   1 
ATOM   12220 N  N     . ARG C 1 518 ? -10.456 -21.759 -54.395  1.00 60.02  ? 518 ARG C N     1 
ATOM   12221 C  CA    . ARG C 1 518 ? -10.689 -21.891 -55.822  1.00 57.44  ? 518 ARG C CA    1 
ATOM   12222 C  C     . ARG C 1 518 ? -9.587  -21.280 -56.684  1.00 57.96  ? 518 ARG C C     1 
ATOM   12223 O  O     . ARG C 1 518 ? -9.652  -21.438 -57.893  1.00 69.16  ? 518 ARG C O     1 
ATOM   12224 C  CB    . ARG C 1 518 ? -12.050 -21.287 -56.178  1.00 56.65  ? 518 ARG C CB    1 
ATOM   12225 C  CG    . ARG C 1 518 ? -13.227 -22.060 -55.603  1.00 54.58  ? 518 ARG C CG    1 
ATOM   12226 C  CD    . ARG C 1 518 ? -14.552 -21.743 -56.252  1.00 56.38  ? 518 ARG C CD    1 
ATOM   12227 N  NE    . ARG C 1 518 ? -15.630 -22.494 -55.620  1.00 70.63  ? 518 ARG C NE    1 
ATOM   12228 C  CZ    . ARG C 1 518 ? -15.811 -23.816 -55.713  1.00 81.41  ? 518 ARG C CZ    1 
ATOM   12229 N  NH1   . ARG C 1 518 ? -15.054 -24.540 -56.519  1.00 85.04  ? 518 ARG C NH1   1 
ATOM   12230 N  NH2   . ARG C 1 518 ? -16.770 -24.416 -55.020  1.00 72.01  ? 518 ARG C NH2   1 
ATOM   12231 N  N     . ARG C 1 519 ? -8.552  -20.640 -56.131  1.00 59.10  ? 519 ARG C N     1 
ATOM   12232 C  CA    . ARG C 1 519 ? -7.705  -19.844 -57.015  1.00 71.38  ? 519 ARG C CA    1 
ATOM   12233 C  C     . ARG C 1 519 ? -6.321  -20.480 -57.214  1.00 72.77  ? 519 ARG C C     1 
ATOM   12234 O  O     . ARG C 1 519 ? -6.129  -21.603 -56.734  1.00 64.05  ? 519 ARG C O     1 
ATOM   12235 C  CB    . ARG C 1 519 ? -7.600  -18.405 -56.505  1.00 65.42  ? 519 ARG C CB    1 
ATOM   12236 C  CG    . ARG C 1 519 ? -6.850  -18.271 -55.200  1.00 60.44  ? 519 ARG C CG    1 
ATOM   12237 C  CD    . ARG C 1 519 ? -6.687  -16.828 -54.770  1.00 60.32  ? 519 ARG C CD    1 
ATOM   12238 N  NE    . ARG C 1 519 ? -5.915  -16.848 -53.531  1.00 58.18  ? 519 ARG C NE    1 
ATOM   12239 C  CZ    . ARG C 1 519 ? -6.399  -16.639 -52.307  1.00 57.50  ? 519 ARG C CZ    1 
ATOM   12240 N  NH1   . ARG C 1 519 ? -7.546  -16.004 -52.121  1.00 59.37  ? 519 ARG C NH1   1 
ATOM   12241 N  NH2   . ARG C 1 519 ? -5.685  -17.009 -51.260  1.00 63.34  ? 519 ARG C NH2   1 
HETATM 12242 P  PA    . FAD D 2 .   ? -31.434 -18.262 -6.819   1.00 54.50  ? 601 FAD A PA    1 
HETATM 12243 O  O1A   . FAD D 2 .   ? -31.218 -18.937 -8.139   1.00 53.51  ? 601 FAD A O1A   1 
HETATM 12244 O  O2A   . FAD D 2 .   ? -31.017 -18.947 -5.555   1.00 56.47  ? 601 FAD A O2A   1 
HETATM 12245 O  O5B   . FAD D 2 .   ? -30.784 -16.786 -6.825   1.00 51.17  ? 601 FAD A O5B   1 
HETATM 12246 C  C5B   . FAD D 2 .   ? -30.775 -15.880 -7.938   1.00 47.57  ? 601 FAD A C5B   1 
HETATM 12247 C  C4B   . FAD D 2 .   ? -29.465 -15.133 -7.907   1.00 53.67  ? 601 FAD A C4B   1 
HETATM 12248 O  O4B   . FAD D 2 .   ? -29.418 -14.285 -6.722   1.00 50.66  ? 601 FAD A O4B   1 
HETATM 12249 C  C3B   . FAD D 2 .   ? -28.189 -15.990 -7.800   1.00 58.57  ? 601 FAD A C3B   1 
HETATM 12250 O  O3B   . FAD D 2 .   ? -27.661 -16.456 -9.034   1.00 58.97  ? 601 FAD A O3B   1 
HETATM 12251 C  C2B   . FAD D 2 .   ? -27.206 -14.994 -7.178   1.00 57.31  ? 601 FAD A C2B   1 
HETATM 12252 O  O2B   . FAD D 2 .   ? -26.684 -14.095 -8.140   1.00 54.69  ? 601 FAD A O2B   1 
HETATM 12253 C  C1B   . FAD D 2 .   ? -28.112 -14.301 -6.161   1.00 54.59  ? 601 FAD A C1B   1 
HETATM 12254 N  N9A   . FAD D 2 .   ? -28.208 -14.928 -4.822   1.00 54.02  ? 601 FAD A N9A   1 
HETATM 12255 C  C8A   . FAD D 2 .   ? -29.118 -15.885 -4.424   1.00 54.68  ? 601 FAD A C8A   1 
HETATM 12256 N  N7A   . FAD D 2 .   ? -28.993 -16.219 -3.161   1.00 56.48  ? 601 FAD A N7A   1 
HETATM 12257 C  C5A   . FAD D 2 .   ? -27.948 -15.431 -2.696   1.00 53.48  ? 601 FAD A C5A   1 
HETATM 12258 C  C6A   . FAD D 2 .   ? -27.368 -15.301 -1.419   1.00 52.46  ? 601 FAD A C6A   1 
HETATM 12259 N  N6A   . FAD D 2 .   ? -27.764 -16.022 -0.374   1.00 45.80  ? 601 FAD A N6A   1 
HETATM 12260 N  N1A   . FAD D 2 .   ? -26.323 -14.439 -1.291   1.00 44.95  ? 601 FAD A N1A   1 
HETATM 12261 C  C2A   . FAD D 2 .   ? -25.945 -13.741 -2.376   1.00 55.92  ? 601 FAD A C2A   1 
HETATM 12262 N  N3A   . FAD D 2 .   ? -26.451 -13.746 -3.614   1.00 50.99  ? 601 FAD A N3A   1 
HETATM 12263 C  C4A   . FAD D 2 .   ? -27.462 -14.625 -3.709   1.00 55.32  ? 601 FAD A C4A   1 
HETATM 12264 N  N1    . FAD D 2 .   ? -38.985 -14.665 -11.624  1.00 61.94  ? 601 FAD A N1    1 
HETATM 12265 C  C2    . FAD D 2 .   ? -39.741 -13.800 -10.887  1.00 55.72  ? 601 FAD A C2    1 
HETATM 12266 O  O2    . FAD D 2 .   ? -39.210 -13.027 -10.086  1.00 50.89  ? 601 FAD A O2    1 
HETATM 12267 N  N3    . FAD D 2 .   ? -41.104 -13.737 -11.012  1.00 53.03  ? 601 FAD A N3    1 
HETATM 12268 C  C4    . FAD D 2 .   ? -41.783 -14.561 -11.883  1.00 50.84  ? 601 FAD A C4    1 
HETATM 12269 O  O4    . FAD D 2 .   ? -43.003 -14.477 -11.936  1.00 46.27  ? 601 FAD A O4    1 
HETATM 12270 C  C4X   . FAD D 2 .   ? -41.006 -15.512 -12.673  1.00 59.37  ? 601 FAD A C4X   1 
HETATM 12271 N  N5    . FAD D 2 .   ? -41.615 -16.325 -13.519  1.00 64.16  ? 601 FAD A N5    1 
HETATM 12272 C  C5X   . FAD D 2 .   ? -40.836 -17.185 -14.258  1.00 62.94  ? 601 FAD A C5X   1 
HETATM 12273 C  C6    . FAD D 2 .   ? -41.480 -18.065 -15.153  1.00 69.07  ? 601 FAD A C6    1 
HETATM 12274 C  C7    . FAD D 2 .   ? -40.785 -18.974 -15.919  1.00 65.66  ? 601 FAD A C7    1 
HETATM 12275 C  C7M   . FAD D 2 .   ? -41.538 -19.876 -16.870  1.00 67.55  ? 601 FAD A C7M   1 
HETATM 12276 C  C8    . FAD D 2 .   ? -39.368 -19.038 -15.808  1.00 64.64  ? 601 FAD A C8    1 
HETATM 12277 C  C8M   . FAD D 2 .   ? -38.547 -19.921 -16.734  1.00 67.19  ? 601 FAD A C8M   1 
HETATM 12278 C  C9    . FAD D 2 .   ? -38.723 -18.166 -14.935  1.00 68.21  ? 601 FAD A C9    1 
HETATM 12279 C  C9A   . FAD D 2 .   ? -39.431 -17.240 -14.140  1.00 64.90  ? 601 FAD A C9A   1 
HETATM 12280 N  N10   . FAD D 2 .   ? -38.816 -16.373 -13.226  1.00 62.64  ? 601 FAD A N10   1 
HETATM 12281 C  C10   . FAD D 2 .   ? -39.577 -15.482 -12.473  1.00 60.16  ? 601 FAD A C10   1 
HETATM 12282 C  "C1'" . FAD D 2 .   ? -37.347 -16.381 -13.052  1.00 59.48  ? 601 FAD A "C1'" 1 
HETATM 12283 C  "C2'" . FAD D 2 .   ? -36.857 -17.372 -11.958  1.00 57.23  ? 601 FAD A "C2'" 1 
HETATM 12284 O  "O2'" . FAD D 2 .   ? -37.186 -18.735 -12.284  1.00 54.27  ? 601 FAD A "O2'" 1 
HETATM 12285 C  "C3'" . FAD D 2 .   ? -37.383 -17.052 -10.546  1.00 50.81  ? 601 FAD A "C3'" 1 
HETATM 12286 O  "O3'" . FAD D 2 .   ? -37.074 -15.704 -10.217  1.00 44.58  ? 601 FAD A "O3'" 1 
HETATM 12287 C  "C4'" . FAD D 2 .   ? -36.796 -17.886 -9.411   1.00 45.89  ? 601 FAD A "C4'" 1 
HETATM 12288 O  "O4'" . FAD D 2 .   ? -37.606 -17.667 -8.260   1.00 42.84  ? 601 FAD A "O4'" 1 
HETATM 12289 C  "C5'" . FAD D 2 .   ? -35.355 -17.514 -9.101   1.00 53.28  ? 601 FAD A "C5'" 1 
HETATM 12290 O  "O5'" . FAD D 2 .   ? -34.535 -18.655 -8.635   1.00 49.67  ? 601 FAD A "O5'" 1 
HETATM 12291 P  P     . FAD D 2 .   ? -34.283 -18.881 -7.059   1.00 49.31  ? 601 FAD A P     1 
HETATM 12292 O  O1P   . FAD D 2 .   ? -35.485 -18.304 -6.384   1.00 51.33  ? 601 FAD A O1P   1 
HETATM 12293 O  O2P   . FAD D 2 .   ? -33.904 -20.324 -6.789   1.00 45.14  ? 601 FAD A O2P   1 
HETATM 12294 O  O3P   . FAD D 2 .   ? -33.010 -17.951 -6.720   1.00 51.81  ? 601 FAD A O3P   1 
HETATM 12295 C  C1    . PEG E 3 .   ? -71.027 -19.252 -18.735  1.00 68.89  ? 602 PEG A C1    1 
HETATM 12296 O  O1    . PEG E 3 .   ? -70.736 -18.603 -19.963  1.00 67.03  ? 602 PEG A O1    1 
HETATM 12297 C  C2    . PEG E 3 .   ? -69.819 -19.897 -18.133  1.00 67.30  ? 602 PEG A C2    1 
HETATM 12298 O  O2    . PEG E 3 .   ? -70.099 -21.242 -17.742  1.00 69.39  ? 602 PEG A O2    1 
HETATM 12299 C  C3    . PEG E 3 .   ? -70.118 -22.180 -18.818  1.00 70.59  ? 602 PEG A C3    1 
HETATM 12300 C  C4    . PEG E 3 .   ? -69.449 -23.465 -18.395  1.00 65.91  ? 602 PEG A C4    1 
HETATM 12301 O  O4    . PEG E 3 .   ? -69.386 -24.427 -19.441  1.00 60.26  ? 602 PEG A O4    1 
HETATM 12302 CL CL    . CL  F 4 .   ? -47.874 -4.070  -6.550   1.00 70.33  ? 603 CL  A CL    1 
HETATM 12303 CL CL    . CL  G 4 .   ? -52.563 -34.131 -29.667  1.00 77.44  ? 604 CL  A CL    1 
HETATM 12304 CL CL    . CL  H 4 .   ? -66.880 -8.130  -7.627   1.00 82.54  ? 605 CL  A CL    1 
HETATM 12305 P  PA    . FAD I 2 .   ? -2.856  14.530  -39.472  1.00 54.01  ? 601 FAD B PA    1 
HETATM 12306 O  O1A   . FAD I 2 .   ? -2.563  14.844  -38.030  1.00 50.78  ? 601 FAD B O1A   1 
HETATM 12307 O  O2A   . FAD I 2 .   ? -1.650  14.341  -40.341  1.00 58.10  ? 601 FAD B O2A   1 
HETATM 12308 O  O5B   . FAD I 2 .   ? -3.832  13.261  -39.585  1.00 53.91  ? 601 FAD B O5B   1 
HETATM 12309 C  C5B   . FAD I 2 .   ? -4.921  13.047  -38.621  1.00 54.24  ? 601 FAD B C5B   1 
HETATM 12310 C  C4B   . FAD I 2 .   ? -5.052  11.566  -38.338  1.00 52.09  ? 601 FAD B C4B   1 
HETATM 12311 O  O4B   . FAD I 2 .   ? -5.413  10.845  -39.551  1.00 50.26  ? 601 FAD B O4B   1 
HETATM 12312 C  C3B   . FAD I 2 .   ? -3.764  10.869  -37.873  1.00 55.02  ? 601 FAD B C3B   1 
HETATM 12313 O  O3B   . FAD I 2 .   ? -3.538  11.025  -36.481  1.00 56.28  ? 601 FAD B O3B   1 
HETATM 12314 C  C2B   . FAD I 2 .   ? -4.030  9.413   -38.267  1.00 54.78  ? 601 FAD B C2B   1 
HETATM 12315 O  O2B   . FAD I 2 .   ? -4.886  8.725   -37.378  1.00 62.14  ? 601 FAD B O2B   1 
HETATM 12316 C  C1B   . FAD I 2 .   ? -4.688  9.619   -39.628  1.00 54.29  ? 601 FAD B C1B   1 
HETATM 12317 N  N9A   . FAD I 2 .   ? -3.751  9.724   -40.750  1.00 51.12  ? 601 FAD B N9A   1 
HETATM 12318 C  C8A   . FAD I 2 .   ? -3.259  10.901  -41.261  1.00 54.63  ? 601 FAD B C8A   1 
HETATM 12319 N  N7A   . FAD I 2 .   ? -2.467  10.723  -42.288  1.00 50.25  ? 601 FAD B N7A   1 
HETATM 12320 C  C5A   . FAD I 2 .   ? -2.425  9.347   -42.457  1.00 53.84  ? 601 FAD B C5A   1 
HETATM 12321 C  C6A   . FAD I 2 .   ? -1.768  8.541   -43.408  1.00 49.35  ? 601 FAD B C6A   1 
HETATM 12322 N  N6A   . FAD I 2 .   ? -0.991  9.039   -44.361  1.00 45.28  ? 601 FAD B N6A   1 
HETATM 12323 N  N1A   . FAD I 2 .   ? -1.957  7.199   -43.328  1.00 47.18  ? 601 FAD B N1A   1 
HETATM 12324 C  C2A   . FAD I 2 .   ? -2.717  6.729   -42.322  1.00 49.13  ? 601 FAD B C2A   1 
HETATM 12325 N  N3A   . FAD I 2 .   ? -3.400  7.390   -41.388  1.00 48.85  ? 601 FAD B N3A   1 
HETATM 12326 C  C4A   . FAD I 2 .   ? -3.205  8.715   -41.505  1.00 55.75  ? 601 FAD B C4A   1 
HETATM 12327 N  N1    . FAD I 2 .   ? -10.469 20.339  -38.630  1.00 51.28  ? 601 FAD B N1    1 
HETATM 12328 C  C2    . FAD I 2 .   ? -11.211 20.432  -39.781  1.00 52.40  ? 601 FAD B C2    1 
HETATM 12329 O  O2    . FAD I 2 .   ? -11.381 19.460  -40.525  1.00 48.59  ? 601 FAD B O2    1 
HETATM 12330 N  N3    . FAD I 2 .   ? -11.808 21.587  -40.155  1.00 49.46  ? 601 FAD B N3    1 
HETATM 12331 C  C4    . FAD I 2 .   ? -11.676 22.742  -39.427  1.00 47.57  ? 601 FAD B C4    1 
HETATM 12332 O  O4    . FAD I 2 .   ? -12.196 23.761  -39.855  1.00 46.02  ? 601 FAD B O4    1 
HETATM 12333 C  C4X   . FAD I 2 .   ? -10.888 22.703  -38.223  1.00 55.83  ? 601 FAD B C4X   1 
HETATM 12334 N  N5    . FAD I 2 .   ? -10.751 23.807  -37.502  1.00 57.60  ? 601 FAD B N5    1 
HETATM 12335 C  C5X   . FAD I 2 .   ? -9.996  23.720  -36.353  1.00 59.99  ? 601 FAD B C5X   1 
HETATM 12336 C  C6    . FAD I 2 .   ? -9.823  24.888  -35.584  1.00 62.07  ? 601 FAD B C6    1 
HETATM 12337 C  C7    . FAD I 2 .   ? -9.080  24.892  -34.425  1.00 58.04  ? 601 FAD B C7    1 
HETATM 12338 C  C7M   . FAD I 2 .   ? -8.940  26.161  -33.620  1.00 59.07  ? 601 FAD B C7M   1 
HETATM 12339 C  C8    . FAD I 2 .   ? -8.469  23.687  -33.995  1.00 60.63  ? 601 FAD B C8    1 
HETATM 12340 C  C8M   . FAD I 2 .   ? -7.756  23.607  -32.660  1.00 59.25  ? 601 FAD B C8M   1 
HETATM 12341 C  C9    . FAD I 2 .   ? -8.622  22.534  -34.745  1.00 58.23  ? 601 FAD B C9    1 
HETATM 12342 C  C9A   . FAD I 2 .   ? -9.372  22.518  -35.933  1.00 55.18  ? 601 FAD B C9A   1 
HETATM 12343 N  N10   . FAD I 2 .   ? -9.515  21.371  -36.726  1.00 48.49  ? 601 FAD B N10   1 
HETATM 12344 C  C10   . FAD I 2 .   ? -10.310 21.418  -37.882  1.00 53.28  ? 601 FAD B C10   1 
HETATM 12345 C  "C1'" . FAD I 2 .   ? -8.927  20.082  -36.288  1.00 44.58  ? 601 FAD B "C1'" 1 
HETATM 12346 C  "C2'" . FAD I 2 .   ? -7.502  19.809  -36.819  1.00 50.55  ? 601 FAD B "C2'" 1 
HETATM 12347 O  "O2'" . FAD I 2 .   ? -6.544  20.753  -36.319  1.00 56.58  ? 601 FAD B "O2'" 1 
HETATM 12348 C  "C3'" . FAD I 2 .   ? -7.418  19.767  -38.354  1.00 54.65  ? 601 FAD B "C3'" 1 
HETATM 12349 O  "O3'" . FAD I 2 .   ? -8.262  18.729  -38.881  1.00 45.11  ? 601 FAD B "O3'" 1 
HETATM 12350 C  "C4'" . FAD I 2 .   ? -6.011  19.504  -38.889  1.00 49.81  ? 601 FAD B "C4'" 1 
HETATM 12351 O  "O4'" . FAD I 2 .   ? -5.924  20.009  -40.216  1.00 44.00  ? 601 FAD B "O4'" 1 
HETATM 12352 C  "C5'" . FAD I 2 .   ? -5.665  18.034  -38.895  1.00 48.42  ? 601 FAD B "C5'" 1 
HETATM 12353 O  "O5'" . FAD I 2 .   ? -4.213  17.846  -38.837  1.00 54.02  ? 601 FAD B "O5'" 1 
HETATM 12354 P  P     . FAD I 2 .   ? -3.404  17.269  -40.107  1.00 49.68  ? 601 FAD B P     1 
HETATM 12355 O  O1P   . FAD I 2 .   ? -4.000  17.904  -41.323  1.00 46.19  ? 601 FAD B O1P   1 
HETATM 12356 O  O2P   . FAD I 2 .   ? -1.914  17.377  -39.865  1.00 47.29  ? 601 FAD B O2P   1 
HETATM 12357 O  O3P   . FAD I 2 .   ? -3.766  15.697  -40.089  1.00 50.50  ? 601 FAD B O3P   1 
HETATM 12358 C  C1    . PEG J 3 .   ? -29.804 36.056  -22.984  1.00 57.61  ? 602 PEG B C1    1 
HETATM 12359 O  O1    . PEG J 3 .   ? -30.009 34.856  -22.313  1.00 55.17  ? 602 PEG B O1    1 
HETATM 12360 C  C2    . PEG J 3 .   ? -28.486 36.105  -23.683  1.00 53.70  ? 602 PEG B C2    1 
HETATM 12361 O  O2    . PEG J 3 .   ? -28.666 36.733  -24.952  1.00 54.28  ? 602 PEG B O2    1 
HETATM 12362 C  C3    . PEG J 3 .   ? -28.758 38.154  -24.898  1.00 57.82  ? 602 PEG B C3    1 
HETATM 12363 C  C4    . PEG J 3 .   ? -29.413 38.678  -26.145  1.00 55.14  ? 602 PEG B C4    1 
HETATM 12364 O  O4    . PEG J 3 .   ? -30.745 39.134  -25.930  1.00 50.11  ? 602 PEG B O4    1 
HETATM 12365 C  C1    . PEG K 3 .   ? -19.628 27.553  -58.816  1.00 68.02  ? 603 PEG B C1    1 
HETATM 12366 O  O1    . PEG K 3 .   ? -19.740 26.500  -57.859  1.00 65.60  ? 603 PEG B O1    1 
HETATM 12367 C  C2    . PEG K 3 .   ? -20.184 27.169  -60.150  1.00 71.08  ? 603 PEG B C2    1 
HETATM 12368 O  O2    . PEG K 3 .   ? -21.363 27.922  -60.435  1.00 78.17  ? 603 PEG B O2    1 
HETATM 12369 C  C3    . PEG K 3 .   ? -21.922 27.645  -61.718  1.00 73.78  ? 603 PEG B C3    1 
HETATM 12370 C  C4    . PEG K 3 .   ? -22.469 26.243  -61.763  1.00 66.13  ? 603 PEG B C4    1 
HETATM 12371 O  O4    . PEG K 3 .   ? -23.660 26.084  -61.007  1.00 61.24  ? 603 PEG B O4    1 
HETATM 12372 CL CL    . CL  L 4 .   ? -23.908 33.237  -23.580  1.00 71.82  ? 604 CL  B CL    1 
HETATM 12373 P  PA    . FAD M 2 .   ? -28.570 -7.025  -60.084  1.00 63.76  ? 601 FAD C PA    1 
HETATM 12374 O  O1A   . FAD M 2 .   ? -28.565 -7.918  -61.285  1.00 65.45  ? 601 FAD C O1A   1 
HETATM 12375 O  O2A   . FAD M 2 .   ? -29.542 -7.358  -58.995  1.00 68.62  ? 601 FAD C O2A   1 
HETATM 12376 O  O5B   . FAD M 2 .   ? -27.082 -6.940  -59.454  1.00 65.58  ? 601 FAD C O5B   1 
HETATM 12377 C  C5B   . FAD M 2 .   ? -25.859 -6.803  -60.260  1.00 57.47  ? 601 FAD C C5B   1 
HETATM 12378 C  C4B   . FAD M 2 .   ? -24.712 -7.532  -59.590  1.00 57.99  ? 601 FAD C C4B   1 
HETATM 12379 O  O4B   . FAD M 2 .   ? -24.343 -6.830  -58.369  1.00 59.11  ? 601 FAD C O4B   1 
HETATM 12380 C  C3B   . FAD M 2 .   ? -24.962 -8.984  -59.125  1.00 62.26  ? 601 FAD C C3B   1 
HETATM 12381 O  O3B   . FAD M 2 .   ? -24.743 -10.004 -60.093  1.00 58.37  ? 601 FAD C O3B   1 
HETATM 12382 C  C2B   . FAD M 2 .   ? -23.913 -9.121  -58.019  1.00 59.64  ? 601 FAD C C2B   1 
HETATM 12383 O  O2B   . FAD M 2 .   ? -22.586 -9.252  -58.491  1.00 59.91  ? 601 FAD C O2B   1 
HETATM 12384 C  C1B   . FAD M 2 .   ? -24.073 -7.765  -57.335  1.00 60.16  ? 601 FAD C C1B   1 
HETATM 12385 N  N9A   . FAD M 2 .   ? -25.152 -7.641  -56.354  1.00 64.12  ? 601 FAD C N9A   1 
HETATM 12386 C  C8A   . FAD M 2 .   ? -26.434 -7.210  -56.612  1.00 58.97  ? 601 FAD C C8A   1 
HETATM 12387 N  N7A   . FAD M 2 .   ? -27.170 -7.138  -55.531  1.00 59.35  ? 601 FAD C N7A   1 
HETATM 12388 C  C5A   . FAD M 2 .   ? -26.318 -7.518  -54.503  1.00 62.64  ? 601 FAD C C5A   1 
HETATM 12389 C  C6A   . FAD M 2 .   ? -26.511 -7.612  -53.114  1.00 54.26  ? 601 FAD C C6A   1 
HETATM 12390 N  N6A   . FAD M 2 .   ? -27.675 -7.349  -52.528  1.00 51.68  ? 601 FAD C N6A   1 
HETATM 12391 N  N1A   . FAD M 2 .   ? -25.458 -8.024  -52.367  1.00 51.36  ? 601 FAD C N1A   1 
HETATM 12392 C  C2A   . FAD M 2 .   ? -24.302 -8.307  -52.993  1.00 52.16  ? 601 FAD C C2A   1 
HETATM 12393 N  N3A   . FAD M 2 .   ? -24.014 -8.245  -54.292  1.00 49.18  ? 601 FAD C N3A   1 
HETATM 12394 C  C4A   . FAD M 2 .   ? -25.071 -7.830  -54.999  1.00 55.86  ? 601 FAD C C4A   1 
HETATM 12395 N  N1    . FAD M 2 .   ? -26.626 0.123   -66.512  1.00 54.06  ? 601 FAD C N1    1 
HETATM 12396 C  C2    . FAD M 2 .   ? -26.442 1.373   -66.008  1.00 52.80  ? 601 FAD C C2    1 
HETATM 12397 O  O2    . FAD M 2 .   ? -25.859 1.539   -64.949  1.00 48.21  ? 601 FAD C O2    1 
HETATM 12398 N  N3    . FAD M 2 .   ? -26.936 2.494   -66.611  1.00 54.81  ? 601 FAD C N3    1 
HETATM 12399 C  C4    . FAD M 2 .   ? -27.638 2.431   -67.785  1.00 52.67  ? 601 FAD C C4    1 
HETATM 12400 O  O4    . FAD M 2 .   ? -28.031 3.479   -68.301  1.00 53.32  ? 601 FAD C O4    1 
HETATM 12401 C  C4X   . FAD M 2 .   ? -27.868 1.115   -68.351  1.00 60.12  ? 601 FAD C C4X   1 
HETATM 12402 N  N5    . FAD M 2 .   ? -28.524 1.014   -69.483  1.00 61.43  ? 601 FAD C N5    1 
HETATM 12403 C  C5X   . FAD M 2 .   ? -28.704 -0.238  -70.008  1.00 67.45  ? 601 FAD C C5X   1 
HETATM 12404 C  C6    . FAD M 2 .   ? -29.426 -0.341  -71.214  1.00 73.44  ? 601 FAD C C6    1 
HETATM 12405 C  C7    . FAD M 2 .   ? -29.661 -1.557  -71.813  1.00 73.43  ? 601 FAD C C7    1 
HETATM 12406 C  C7M   . FAD M 2 .   ? -30.442 -1.640  -73.102  1.00 69.51  ? 601 FAD C C7M   1 
HETATM 12407 C  C8    . FAD M 2 .   ? -29.167 -2.730  -71.204  1.00 77.68  ? 601 FAD C C8    1 
HETATM 12408 C  C8M   . FAD M 2 .   ? -29.384 -4.065  -71.872  1.00 82.96  ? 601 FAD C C8M   1 
HETATM 12409 C  C9    . FAD M 2 .   ? -28.453 -2.650  -70.016  1.00 71.32  ? 601 FAD C C9    1 
HETATM 12410 C  C9A   . FAD M 2 .   ? -28.213 -1.411  -69.388  1.00 69.66  ? 601 FAD C C9A   1 
HETATM 12411 N  N10   . FAD M 2 .   ? -27.521 -1.275  -68.178  1.00 68.39  ? 601 FAD C N10   1 
HETATM 12412 C  C10   . FAD M 2 .   ? -27.307 -0.007  -67.634  1.00 62.94  ? 601 FAD C C10   1 
HETATM 12413 C  "C1'" . FAD M 2 .   ? -26.960 -2.466  -67.496  1.00 62.93  ? 601 FAD C "C1'" 1 
HETATM 12414 C  "C2'" . FAD M 2 .   ? -27.931 -3.131  -66.492  1.00 64.39  ? 601 FAD C "C2'" 1 
HETATM 12415 O  "O2'" . FAD M 2 .   ? -29.030 -3.762  -67.153  1.00 55.99  ? 601 FAD C "O2'" 1 
HETATM 12416 C  "C3'" . FAD M 2 .   ? -28.474 -2.164  -65.427  1.00 63.27  ? 601 FAD C "C3'" 1 
HETATM 12417 O  "O3'" . FAD M 2 .   ? -27.369 -1.510  -64.779  1.00 53.10  ? 601 FAD C "O3'" 1 
HETATM 12418 C  "C4'" . FAD M 2 .   ? -29.359 -2.841  -64.371  1.00 62.94  ? 601 FAD C "C4'" 1 
HETATM 12419 O  "O4'" . FAD M 2 .   ? -30.010 -1.846  -63.585  1.00 58.67  ? 601 FAD C "O4'" 1 
HETATM 12420 C  "C5'" . FAD M 2 .   ? -28.600 -3.758  -63.434  1.00 67.17  ? 601 FAD C "C5'" 1 
HETATM 12421 O  "O5'" . FAD M 2 .   ? -29.446 -4.881  -63.008  1.00 62.07  ? 601 FAD C "O5'" 1 
HETATM 12422 P  P     . FAD M 2 .   ? -30.046 -4.924  -61.515  1.00 57.14  ? 601 FAD C P     1 
HETATM 12423 O  O1P   . FAD M 2 .   ? -30.259 -3.479  -61.198  1.00 52.38  ? 601 FAD C O1P   1 
HETATM 12424 O  O2P   . FAD M 2 .   ? -31.188 -5.891  -61.432  1.00 59.93  ? 601 FAD C O2P   1 
HETATM 12425 O  O3P   . FAD M 2 .   ? -28.838 -5.526  -60.616  1.00 55.64  ? 601 FAD C O3P   1 
HETATM 12426 O  O     . HOH N 5 .   ? -34.806 -4.156  4.259    1.00 36.13  ? 701 HOH A O     1 
HETATM 12427 O  O     . HOH N 5 .   ? -64.912 -18.034 -21.245  1.00 36.83  ? 702 HOH A O     1 
HETATM 12428 O  O     . HOH N 5 .   ? -36.184 -22.621 -31.648  1.00 47.93  ? 703 HOH A O     1 
HETATM 12429 O  O     . HOH N 5 .   ? -35.697 -10.279 -17.281  1.00 46.99  ? 704 HOH A O     1 
HETATM 12430 O  O     . HOH N 5 .   ? -62.660 -12.879 -24.588  1.00 38.86  ? 705 HOH A O     1 
HETATM 12431 O  O     . HOH N 5 .   ? -67.249 -8.054  -4.769   1.00 56.34  ? 706 HOH A O     1 
HETATM 12432 O  O     . HOH N 5 .   ? -16.375 11.028  -15.806  1.00 45.64  ? 707 HOH A O     1 
HETATM 12433 O  O     . HOH N 5 .   ? -61.962 -19.359 -36.354  1.00 45.59  ? 708 HOH A O     1 
HETATM 12434 O  O     . HOH N 5 .   ? -50.419 -5.981  4.666    1.00 34.91  ? 709 HOH A O     1 
HETATM 12435 O  O     . HOH N 5 .   ? -26.329 -26.547 1.025    1.00 43.44  ? 710 HOH A O     1 
HETATM 12436 O  O     . HOH N 5 .   ? -12.066 0.020   -2.889   1.00 46.14  ? 711 HOH A O     1 
HETATM 12437 O  O     . HOH N 5 .   ? -22.208 -25.807 11.432   1.00 41.58  ? 712 HOH A O     1 
HETATM 12438 O  O     . HOH N 5 .   ? -26.338 -6.442  -27.231  1.00 50.25  ? 713 HOH A O     1 
HETATM 12439 O  O     . HOH N 5 .   ? -53.207 -18.279 -0.654   1.00 49.03  ? 714 HOH A O     1 
HETATM 12440 O  O     . HOH N 5 .   ? -39.444 -14.033 -2.655   1.00 36.40  ? 715 HOH A O     1 
HETATM 12441 O  O     . HOH N 5 .   ? -33.126 -4.623  -10.664  1.00 38.07  ? 716 HOH A O     1 
HETATM 12442 O  O     . HOH N 5 .   ? -55.477 1.828   -28.582  1.00 44.11  ? 717 HOH A O     1 
HETATM 12443 O  O     . HOH N 5 .   ? -29.341 -10.455 16.024   1.00 41.00  ? 718 HOH A O     1 
HETATM 12444 O  O     . HOH N 5 .   ? -36.273 -4.055  -31.592  1.00 42.99  ? 719 HOH A O     1 
HETATM 12445 O  O     . HOH N 5 .   ? -17.931 6.655   -9.780   1.00 40.99  ? 720 HOH A O     1 
HETATM 12446 O  O     . HOH N 5 .   ? -16.849 8.021   -14.539  1.00 44.74  ? 721 HOH A O     1 
HETATM 12447 O  O     . HOH N 5 .   ? -61.894 -9.183  -26.084  1.00 44.31  ? 722 HOH A O     1 
HETATM 12448 O  O     . HOH N 5 .   ? -48.207 -8.100  -8.134   1.00 35.29  ? 723 HOH A O     1 
HETATM 12449 O  O     . HOH N 5 .   ? -58.312 4.685   -15.929  1.00 38.41  ? 724 HOH A O     1 
HETATM 12450 O  O     . HOH N 5 .   ? -40.769 -1.519  -20.864  1.00 39.01  ? 725 HOH A O     1 
HETATM 12451 O  O     . HOH N 5 .   ? -26.975 0.489   9.122    1.00 41.17  ? 726 HOH A O     1 
HETATM 12452 O  O     . HOH N 5 .   ? -28.196 0.506   -27.379  1.00 39.26  ? 727 HOH A O     1 
HETATM 12453 O  O     . HOH N 5 .   ? -38.659 -9.532  14.016   1.00 41.30  ? 728 HOH A O     1 
HETATM 12454 O  O     . HOH N 5 .   ? -60.993 -1.646  -29.693  1.00 42.46  ? 729 HOH A O     1 
HETATM 12455 O  O     . HOH N 5 .   ? -11.614 -11.167 -0.562   1.00 42.93  ? 730 HOH A O     1 
HETATM 12456 O  O     . HOH N 5 .   ? -41.330 -25.022 -27.431  1.00 35.71  ? 731 HOH A O     1 
HETATM 12457 O  O     . HOH N 5 .   ? -54.948 -20.570 -22.534  1.00 43.59  ? 732 HOH A O     1 
HETATM 12458 O  O     . HOH N 5 .   ? -23.221 5.281   -14.593  1.00 35.64  ? 733 HOH A O     1 
HETATM 12459 O  O     . HOH N 5 .   ? -59.705 -20.553 -22.316  1.00 41.61  ? 734 HOH A O     1 
HETATM 12460 O  O     . HOH N 5 .   ? -45.918 -20.348 -9.203   1.00 44.56  ? 735 HOH A O     1 
HETATM 12461 O  O     . HOH N 5 .   ? -44.694 -11.846 0.806    1.00 32.14  ? 736 HOH A O     1 
HETATM 12462 O  O     . HOH N 5 .   ? -42.807 -2.019  9.383    1.00 38.26  ? 737 HOH A O     1 
HETATM 12463 O  O     . HOH N 5 .   ? -46.699 -14.446 -33.080  1.00 39.35  ? 738 HOH A O     1 
HETATM 12464 O  O     . HOH N 5 .   ? -49.195 -12.531 -0.860   1.00 38.21  ? 739 HOH A O     1 
HETATM 12465 O  O     . HOH N 5 .   ? -61.154 -4.631  -27.241  1.00 46.41  ? 740 HOH A O     1 
HETATM 12466 O  O     . HOH N 5 .   ? -35.666 -4.267  0.998    1.00 46.23  ? 741 HOH A O     1 
HETATM 12467 O  O     . HOH N 5 .   ? -47.895 -14.585 -6.599   1.00 38.47  ? 742 HOH A O     1 
HETATM 12468 O  O     . HOH N 5 .   ? -28.791 -19.545 8.222    1.00 34.85  ? 743 HOH A O     1 
HETATM 12469 O  O     . HOH N 5 .   ? -66.235 -26.560 -20.266  1.00 40.04  ? 744 HOH A O     1 
HETATM 12470 O  O     . HOH N 5 .   ? -47.363 -12.319 1.096    1.00 34.99  ? 745 HOH A O     1 
HETATM 12471 O  O     . HOH N 5 .   ? -39.217 -6.108  -24.299  1.00 36.95  ? 746 HOH A O     1 
HETATM 12472 O  O     . HOH N 5 .   ? -15.399 -7.968  4.057    1.00 52.63  ? 747 HOH A O     1 
HETATM 12473 O  O     . HOH N 5 .   ? -28.599 -24.953 -13.154  1.00 57.77  ? 748 HOH A O     1 
HETATM 12474 O  O     . HOH N 5 .   ? -33.696 -4.683  6.667    1.00 38.97  ? 749 HOH A O     1 
HETATM 12475 O  O     . HOH N 5 .   ? -70.955 -2.871  -2.469   1.00 61.27  ? 750 HOH A O     1 
HETATM 12476 O  O     . HOH N 5 .   ? -38.211 -7.531  -5.972   1.00 35.75  ? 751 HOH A O     1 
HETATM 12477 O  O     . HOH N 5 .   ? -50.384 -18.174 -0.279   1.00 34.81  ? 752 HOH A O     1 
HETATM 12478 O  O     . HOH N 5 .   ? -23.132 -9.772  -21.151  1.00 42.88  ? 753 HOH A O     1 
HETATM 12479 O  O     . HOH N 5 .   ? -35.500 -19.139 0.903    1.00 39.90  ? 754 HOH A O     1 
HETATM 12480 O  O     . HOH N 5 .   ? -48.916 -13.065 -29.003  1.00 36.44  ? 755 HOH A O     1 
HETATM 12481 O  O     . HOH N 5 .   ? -42.522 -27.229 4.538    1.00 49.69  ? 756 HOH A O     1 
HETATM 12482 O  O     . HOH N 5 .   ? -30.878 -2.882  -20.750  1.00 35.17  ? 757 HOH A O     1 
HETATM 12483 O  O     . HOH N 5 .   ? -21.665 0.323   -16.441  1.00 40.27  ? 758 HOH A O     1 
HETATM 12484 O  O     . HOH N 5 .   ? -49.336 7.559   -24.695  1.00 42.92  ? 759 HOH A O     1 
HETATM 12485 O  O     . HOH N 5 .   ? -24.311 -12.571 -26.628  1.00 53.51  ? 760 HOH A O     1 
HETATM 12486 O  O     . HOH N 5 .   ? -46.519 -27.026 -31.076  1.00 41.33  ? 761 HOH A O     1 
HETATM 12487 O  O     . HOH N 5 .   ? -34.269 -5.098  10.625   1.00 32.11  ? 762 HOH A O     1 
HETATM 12488 O  O     . HOH N 5 .   ? -5.486  -21.884 -14.505  1.00 57.38  ? 763 HOH A O     1 
HETATM 12489 O  O     . HOH N 5 .   ? -29.172 -1.427  9.136    1.00 41.36  ? 764 HOH A O     1 
HETATM 12490 O  O     . HOH N 5 .   ? -32.080 -2.298  -23.057  1.00 38.45  ? 765 HOH A O     1 
HETATM 12491 O  O     . HOH N 5 .   ? -41.775 -17.137 -28.332  1.00 46.69  ? 766 HOH A O     1 
HETATM 12492 O  O     . HOH N 5 .   ? -57.220 -19.818 -21.389  1.00 40.50  ? 767 HOH A O     1 
HETATM 12493 O  O     . HOH N 5 .   ? -42.195 -13.576 -1.803   1.00 36.52  ? 768 HOH A O     1 
HETATM 12494 O  O     . HOH N 5 .   ? -59.129 -7.586  3.858    1.00 43.80  ? 769 HOH A O     1 
HETATM 12495 O  O     . HOH N 5 .   ? -45.201 -5.367  -3.389   1.00 36.40  ? 770 HOH A O     1 
HETATM 12496 O  O     . HOH N 5 .   ? -52.828 6.256   -3.632   1.00 41.20  ? 771 HOH A O     1 
HETATM 12497 O  O     . HOH N 5 .   ? -43.194 -10.978 -1.245   1.00 33.37  ? 772 HOH A O     1 
HETATM 12498 O  O     . HOH N 5 .   ? -39.507 -0.507  7.725    1.00 40.64  ? 773 HOH A O     1 
HETATM 12499 O  O     . HOH N 5 .   ? -28.984 -0.892  12.188   1.00 36.79  ? 774 HOH A O     1 
HETATM 12500 O  O     . HOH N 5 .   ? -48.039 -10.196 -32.551  1.00 49.44  ? 775 HOH A O     1 
HETATM 12501 O  O     . HOH N 5 .   ? -27.332 -10.870 -4.685   1.00 43.51  ? 776 HOH A O     1 
HETATM 12502 O  O     . HOH N 5 .   ? -67.938 -8.365  -21.060  1.00 44.84  ? 777 HOH A O     1 
HETATM 12503 O  O     . HOH N 5 .   ? -55.470 -2.650  -0.764   1.00 50.52  ? 778 HOH A O     1 
HETATM 12504 O  O     . HOH N 5 .   ? -28.018 2.830   -22.556  1.00 40.74  ? 779 HOH A O     1 
HETATM 12505 O  O     . HOH N 5 .   ? -19.493 -4.310  -16.595  1.00 52.93  ? 780 HOH A O     1 
HETATM 12506 O  O     . HOH N 5 .   ? -54.189 -14.949 -42.098  1.00 43.74  ? 781 HOH A O     1 
HETATM 12507 O  O     . HOH N 5 .   ? -43.822 -14.431 0.125    1.00 38.10  ? 782 HOH A O     1 
HETATM 12508 O  O     . HOH N 5 .   ? -38.902 -3.634  -24.942  1.00 37.28  ? 783 HOH A O     1 
HETATM 12509 O  O     . HOH N 5 .   ? -22.876 -1.619  -25.448  1.00 62.48  ? 784 HOH A O     1 
HETATM 12510 O  O     . HOH N 5 .   ? -64.194 -13.275 -1.771   1.00 42.87  ? 785 HOH A O     1 
HETATM 12511 O  O     . HOH N 5 .   ? -48.263 -27.205 -10.312  1.00 47.29  ? 786 HOH A O     1 
HETATM 12512 O  O     . HOH N 5 .   ? -29.963 -10.259 -12.918  1.00 47.65  ? 787 HOH A O     1 
HETATM 12513 O  O     . HOH N 5 .   ? -44.617 -9.337  -38.374  1.00 53.12  ? 788 HOH A O     1 
HETATM 12514 O  O     . HOH N 5 .   ? -39.042 -24.454 -28.565  1.00 44.68  ? 789 HOH A O     1 
HETATM 12515 O  O     . HOH N 5 .   ? -15.864 -6.694  8.003    1.00 53.82  ? 790 HOH A O     1 
HETATM 12516 O  O     . HOH N 5 .   ? -29.690 -27.399 -7.636   1.00 55.32  ? 791 HOH A O     1 
HETATM 12517 O  O     . HOH N 5 .   ? -43.578 -1.778  -4.709   1.00 50.89  ? 792 HOH A O     1 
HETATM 12518 O  O     . HOH N 5 .   ? -16.697 -30.577 -20.649  1.00 60.62  ? 793 HOH A O     1 
HETATM 12519 O  O     . HOH N 5 .   ? -43.406 -14.807 -17.276  1.00 59.28  ? 794 HOH A O     1 
HETATM 12520 O  O     . HOH N 5 .   ? -32.236 -15.095 15.275   1.00 56.35  ? 795 HOH A O     1 
HETATM 12521 O  O     . HOH N 5 .   ? -49.635 -10.828 -30.472  1.00 46.77  ? 796 HOH A O     1 
HETATM 12522 O  O     . HOH N 5 .   ? -56.796 -5.653  1.751    1.00 56.35  ? 797 HOH A O     1 
HETATM 12523 O  O     . HOH N 5 .   ? -48.956 -3.309  -0.020   1.00 53.50  ? 798 HOH A O     1 
HETATM 12524 O  O     . HOH N 5 .   ? -40.064 -12.051 -14.735  1.00 64.86  ? 799 HOH A O     1 
HETATM 12525 O  O     . HOH N 5 .   ? -41.996 -0.059  -3.632   1.00 45.88  ? 800 HOH A O     1 
HETATM 12526 O  O     . HOH N 5 .   ? -19.598 -1.469  -16.576  1.00 48.14  ? 801 HOH A O     1 
HETATM 12527 O  O     . HOH N 5 .   ? -48.794 -0.167  -3.995   1.00 63.30  ? 802 HOH A O     1 
HETATM 12528 O  O     . HOH N 5 .   ? -49.804 -27.538 -22.883  1.00 49.20  ? 803 HOH A O     1 
HETATM 12529 O  O     . HOH N 5 .   ? -58.599 6.461   -13.495  1.00 65.13  ? 804 HOH A O     1 
HETATM 12530 O  O     . HOH N 5 .   ? -16.695 -0.384  -14.911  1.00 63.02  ? 805 HOH A O     1 
HETATM 12531 O  O     . HOH N 5 .   ? -57.172 7.662   -21.915  1.00 63.17  ? 806 HOH A O     1 
HETATM 12532 O  O     . HOH N 5 .   ? -60.371 -17.853 -7.065   1.00 52.69  ? 807 HOH A O     1 
HETATM 12533 O  O     . HOH N 5 .   ? -57.995 -0.606  0.927    1.00 55.16  ? 808 HOH A O     1 
HETATM 12534 O  O     . HOH N 5 .   ? -61.267 -5.464  6.673    1.00 60.40  ? 809 HOH A O     1 
HETATM 12535 O  O     . HOH O 5 .   ? 5.103   20.744  -50.281  1.00 51.03  ? 701 HOH B O     1 
HETATM 12536 O  O     . HOH O 5 .   ? -2.371  5.540   -23.578  1.00 54.34  ? 702 HOH B O     1 
HETATM 12537 O  O     . HOH O 5 .   ? -25.091 -10.611 -32.308  1.00 44.05  ? 703 HOH B O     1 
HETATM 12538 O  O     . HOH O 5 .   ? 9.090   12.426  -50.939  1.00 46.36  ? 704 HOH B O     1 
HETATM 12539 O  O     . HOH O 5 .   ? -25.744 42.185  -36.129  1.00 44.55  ? 705 HOH B O     1 
HETATM 12540 O  O     . HOH O 5 .   ? -25.399 17.206  -33.766  1.00 34.71  ? 706 HOH B O     1 
HETATM 12541 O  O     . HOH O 5 .   ? 9.056   12.477  -42.874  1.00 50.19  ? 707 HOH B O     1 
HETATM 12542 O  O     . HOH O 5 .   ? -7.916  17.909  -47.153  1.00 32.91  ? 708 HOH B O     1 
HETATM 12543 O  O     . HOH O 5 .   ? -25.738 17.084  -22.205  1.00 46.72  ? 709 HOH B O     1 
HETATM 12544 O  O     . HOH O 5 .   ? -19.596 -2.031  -33.444  1.00 45.80  ? 710 HOH B O     1 
HETATM 12545 O  O     . HOH O 5 .   ? -15.061 14.360  -30.080  1.00 38.18  ? 711 HOH B O     1 
HETATM 12546 O  O     . HOH O 5 .   ? -29.805 12.213  -23.201  1.00 44.81  ? 712 HOH B O     1 
HETATM 12547 O  O     . HOH O 5 .   ? -15.054 11.320  -62.205  1.00 45.44  ? 713 HOH B O     1 
HETATM 12548 O  O     . HOH O 5 .   ? -26.426 10.628  -35.082  1.00 32.76  ? 714 HOH B O     1 
HETATM 12549 O  O     . HOH O 5 .   ? -10.256 7.795   -34.976  1.00 48.53  ? 715 HOH B O     1 
HETATM 12550 O  O     . HOH O 5 .   ? -0.408  3.360   -61.251  1.00 40.04  ? 716 HOH B O     1 
HETATM 12551 O  O     . HOH O 5 .   ? -23.671 47.413  -23.746  1.00 55.14  ? 717 HOH B O     1 
HETATM 12552 O  O     . HOH O 5 .   ? -33.102 37.685  -34.847  1.00 41.80  ? 718 HOH B O     1 
HETATM 12553 O  O     . HOH O 5 .   ? -22.310 -2.423  -34.724  1.00 36.33  ? 719 HOH B O     1 
HETATM 12554 O  O     . HOH O 5 .   ? -29.038 40.080  -35.522  1.00 43.34  ? 720 HOH B O     1 
HETATM 12555 O  O     . HOH O 5 .   ? -10.919 -2.380  -56.618  1.00 37.73  ? 721 HOH B O     1 
HETATM 12556 O  O     . HOH O 5 .   ? -18.607 25.207  -25.061  1.00 39.71  ? 722 HOH B O     1 
HETATM 12557 O  O     . HOH O 5 .   ? -25.648 22.002  -49.881  1.00 54.71  ? 723 HOH B O     1 
HETATM 12558 O  O     . HOH O 5 .   ? -16.261 40.022  -35.554  1.00 41.45  ? 724 HOH B O     1 
HETATM 12559 O  O     . HOH O 5 .   ? -18.261 -0.679  -31.231  1.00 43.14  ? 725 HOH B O     1 
HETATM 12560 O  O     . HOH O 5 .   ? -18.663 8.782   -21.961  1.00 46.77  ? 726 HOH B O     1 
HETATM 12561 O  O     . HOH O 5 .   ? -36.145 36.718  -33.203  1.00 50.35  ? 727 HOH B O     1 
HETATM 12562 O  O     . HOH O 5 .   ? -14.223 42.624  -34.218  1.00 44.02  ? 728 HOH B O     1 
HETATM 12563 O  O     . HOH O 5 .   ? 4.998   8.867   -51.777  1.00 42.40  ? 729 HOH B O     1 
HETATM 12564 O  O     . HOH O 5 .   ? -37.938 21.243  -35.830  1.00 44.27  ? 730 HOH B O     1 
HETATM 12565 O  O     . HOH O 5 .   ? -17.995 44.705  -38.077  1.00 40.50  ? 731 HOH B O     1 
HETATM 12566 O  O     . HOH O 5 .   ? -20.320 45.724  -38.886  1.00 50.30  ? 732 HOH B O     1 
HETATM 12567 O  O     . HOH O 5 .   ? -17.402 40.671  -51.369  1.00 51.30  ? 733 HOH B O     1 
HETATM 12568 O  O     . HOH O 5 .   ? -19.707 -8.662  -37.527  1.00 44.22  ? 734 HOH B O     1 
HETATM 12569 O  O     . HOH O 5 .   ? -12.039 26.350  -46.522  1.00 37.30  ? 735 HOH B O     1 
HETATM 12570 O  O     . HOH O 5 .   ? -8.226  30.533  -22.924  1.00 38.45  ? 736 HOH B O     1 
HETATM 12571 O  O     . HOH O 5 .   ? -35.586 28.162  -46.479  1.00 44.70  ? 737 HOH B O     1 
HETATM 12572 O  O     . HOH O 5 .   ? -13.980 14.516  -45.170  1.00 37.64  ? 738 HOH B O     1 
HETATM 12573 O  O     . HOH O 5 .   ? -14.122 26.153  -15.496  1.00 55.90  ? 739 HOH B O     1 
HETATM 12574 O  O     . HOH O 5 .   ? -18.797 44.264  -20.248  1.00 44.32  ? 740 HOH B O     1 
HETATM 12575 O  O     . HOH O 5 .   ? -22.374 18.981  -29.333  1.00 38.56  ? 741 HOH B O     1 
HETATM 12576 O  O     . HOH O 5 .   ? -8.348  3.543   -28.637  1.00 48.25  ? 742 HOH B O     1 
HETATM 12577 O  O     . HOH O 5 .   ? -17.483 12.272  -11.894  1.00 42.10  ? 743 HOH B O     1 
HETATM 12578 O  O     . HOH O 5 .   ? -35.313 41.895  -42.746  1.00 46.32  ? 744 HOH B O     1 
HETATM 12579 O  O     . HOH O 5 .   ? -26.105 31.279  -29.084  1.00 35.94  ? 745 HOH B O     1 
HETATM 12580 O  O     . HOH O 5 .   ? -7.322  28.039  -42.477  1.00 38.31  ? 746 HOH B O     1 
HETATM 12581 O  O     . HOH O 5 .   ? -39.149 23.410  -34.747  1.00 49.50  ? 747 HOH B O     1 
HETATM 12582 O  O     . HOH O 5 .   ? -16.699 42.656  -35.142  1.00 42.54  ? 748 HOH B O     1 
HETATM 12583 O  O     . HOH O 5 .   ? -24.677 16.310  -24.774  1.00 40.30  ? 749 HOH B O     1 
HETATM 12584 O  O     . HOH O 5 .   ? -7.707  28.576  -52.228  1.00 39.96  ? 750 HOH B O     1 
HETATM 12585 O  O     . HOH O 5 .   ? -21.203 31.055  -22.077  1.00 40.82  ? 751 HOH B O     1 
HETATM 12586 O  O     . HOH O 5 .   ? -9.013  19.820  -48.811  1.00 36.49  ? 752 HOH B O     1 
HETATM 12587 O  O     . HOH O 5 .   ? -17.903 23.761  -46.724  1.00 34.21  ? 753 HOH B O     1 
HETATM 12588 O  O     . HOH O 5 .   ? -0.791  16.204  -47.790  1.00 39.94  ? 754 HOH B O     1 
HETATM 12589 O  O     . HOH O 5 .   ? -9.837  26.732  -63.528  1.00 49.29  ? 755 HOH B O     1 
HETATM 12590 O  O     . HOH O 5 .   ? -2.837  -6.018  -31.873  1.00 58.80  ? 756 HOH B O     1 
HETATM 12591 O  O     . HOH O 5 .   ? -12.242 25.177  -52.712  1.00 42.06  ? 757 HOH B O     1 
HETATM 12592 O  O     . HOH O 5 .   ? -13.310 9.194   -51.465  1.00 35.07  ? 758 HOH B O     1 
HETATM 12593 O  O     . HOH O 5 .   ? -10.869 22.882  -53.782  1.00 37.57  ? 759 HOH B O     1 
HETATM 12594 O  O     . HOH O 5 .   ? -8.206  21.303  -51.168  1.00 41.86  ? 760 HOH B O     1 
HETATM 12595 O  O     . HOH O 5 .   ? -25.205 7.028   -24.127  1.00 38.71  ? 761 HOH B O     1 
HETATM 12596 O  O     . HOH O 5 .   ? -10.359 20.544  -52.672  1.00 34.33  ? 762 HOH B O     1 
HETATM 12597 O  O     . HOH O 5 .   ? -8.567  6.026   -59.284  1.00 31.82  ? 763 HOH B O     1 
HETATM 12598 O  O     . HOH O 5 .   ? 6.295   19.983  -38.337  1.00 63.63  ? 764 HOH B O     1 
HETATM 12599 O  O     . HOH O 5 .   ? -30.209 11.108  -34.785  1.00 41.41  ? 765 HOH B O     1 
HETATM 12600 O  O     . HOH O 5 .   ? -1.790  -1.464  -69.034  1.00 43.67  ? 766 HOH B O     1 
HETATM 12601 O  O     . HOH O 5 .   ? -22.406 10.882  -28.728  1.00 35.56  ? 767 HOH B O     1 
HETATM 12602 O  O     . HOH O 5 .   ? -11.818 6.080   -25.216  1.00 45.54  ? 768 HOH B O     1 
HETATM 12603 O  O     . HOH O 5 .   ? -9.476  36.298  -21.069  1.00 45.73  ? 769 HOH B O     1 
HETATM 12604 O  O     . HOH O 5 .   ? -12.715 50.151  -38.154  1.00 48.09  ? 770 HOH B O     1 
HETATM 12605 O  O     . HOH O 5 .   ? -14.262 4.073   -50.456  1.00 40.96  ? 771 HOH B O     1 
HETATM 12606 O  O     . HOH O 5 .   ? -10.291 0.164   -56.923  1.00 37.79  ? 772 HOH B O     1 
HETATM 12607 O  O     . HOH O 5 .   ? 6.657   19.515  -54.331  1.00 45.60  ? 773 HOH B O     1 
HETATM 12608 O  O     . HOH O 5 .   ? -5.162  11.247  -63.269  1.00 42.50  ? 774 HOH B O     1 
HETATM 12609 O  O     . HOH O 5 .   ? -37.816 21.119  -45.473  1.00 49.85  ? 775 HOH B O     1 
HETATM 12610 O  O     . HOH O 5 .   ? 8.020   8.358   -52.104  1.00 59.16  ? 776 HOH B O     1 
HETATM 12611 O  O     . HOH O 5 .   ? 1.547   22.358  -61.912  1.00 55.56  ? 777 HOH B O     1 
HETATM 12612 O  O     . HOH O 5 .   ? -11.319 19.296  -50.361  1.00 34.71  ? 778 HOH B O     1 
HETATM 12613 O  O     . HOH O 5 .   ? -2.009  22.099  -65.260  1.00 51.13  ? 779 HOH B O     1 
HETATM 12614 O  O     . HOH O 5 .   ? -20.670 9.413   -30.036  1.00 42.15  ? 780 HOH B O     1 
HETATM 12615 O  O     . HOH O 5 .   ? -36.905 30.053  -33.484  1.00 44.00  ? 781 HOH B O     1 
HETATM 12616 O  O     . HOH O 5 .   ? -17.711 38.381  -57.004  1.00 53.67  ? 782 HOH B O     1 
HETATM 12617 O  O     . HOH O 5 .   ? 13.769  16.818  -44.865  1.00 65.25  ? 783 HOH B O     1 
HETATM 12618 O  O     . HOH O 5 .   ? -30.383 19.814  -55.834  1.00 42.51  ? 784 HOH B O     1 
HETATM 12619 O  O     . HOH O 5 .   ? -30.936 35.248  -26.034  1.00 47.79  ? 785 HOH B O     1 
HETATM 12620 O  O     . HOH O 5 .   ? -6.367  6.637   -41.526  1.00 47.73  ? 786 HOH B O     1 
HETATM 12621 O  O     . HOH O 5 .   ? -15.157 27.204  -24.001  1.00 40.19  ? 787 HOH B O     1 
HETATM 12622 O  O     . HOH O 5 .   ? -17.723 18.774  -50.533  1.00 44.09  ? 788 HOH B O     1 
HETATM 12623 O  O     . HOH O 5 .   ? -9.205  5.695   -26.840  1.00 46.97  ? 789 HOH B O     1 
HETATM 12624 O  O     . HOH O 5 .   ? -15.185 9.489   -59.996  1.00 38.82  ? 790 HOH B O     1 
HETATM 12625 O  O     . HOH O 5 .   ? -29.830 43.830  -42.382  1.00 48.40  ? 791 HOH B O     1 
HETATM 12626 O  O     . HOH O 5 .   ? -13.513 -0.556  -29.321  1.00 55.94  ? 792 HOH B O     1 
HETATM 12627 O  O     . HOH O 5 .   ? -21.208 49.681  -29.321  1.00 59.72  ? 793 HOH B O     1 
HETATM 12628 O  O     . HOH O 5 .   ? -37.626 32.631  -33.781  1.00 61.28  ? 794 HOH B O     1 
HETATM 12629 O  O     . HOH O 5 .   ? -8.719  43.179  -20.035  1.00 56.49  ? 795 HOH B O     1 
HETATM 12630 O  O     . HOH O 5 .   ? 4.627   17.405  -35.716  1.00 50.53  ? 796 HOH B O     1 
HETATM 12631 O  O     . HOH O 5 .   ? -27.019 39.829  -16.759  1.00 45.14  ? 797 HOH B O     1 
HETATM 12632 O  O     . HOH O 5 .   ? -14.756 6.996   -50.513  1.00 48.19  ? 798 HOH B O     1 
HETATM 12633 O  O     . HOH O 5 .   ? -27.864 28.134  -21.281  1.00 61.72  ? 799 HOH B O     1 
HETATM 12634 O  O     . HOH O 5 .   ? 0.000   4.221   -71.609  0.50 42.09  ? 800 HOH B O     1 
HETATM 12635 O  O     . HOH O 5 .   ? -31.626 44.629  -24.834  1.00 67.79  ? 801 HOH B O     1 
HETATM 12636 O  O     . HOH O 5 .   ? -14.492 28.823  -21.705  1.00 59.33  ? 802 HOH B O     1 
HETATM 12637 O  O     . HOH O 5 .   ? -1.689  -8.497  -46.602  1.00 57.30  ? 803 HOH B O     1 
HETATM 12638 O  O     . HOH O 5 .   ? -20.835 21.264  -48.907  1.00 52.93  ? 804 HOH B O     1 
HETATM 12639 O  O     . HOH O 5 .   ? -30.075 41.988  -19.586  1.00 57.88  ? 805 HOH B O     1 
HETATM 12640 O  O     . HOH O 5 .   ? -24.598 39.451  -53.636  1.00 58.20  ? 806 HOH B O     1 
HETATM 12641 O  O     . HOH O 5 .   ? 3.368   23.847  -37.136  1.00 57.55  ? 807 HOH B O     1 
HETATM 12642 O  O     . HOH O 5 .   ? -19.451 19.982  -55.092  1.00 48.82  ? 808 HOH B O     1 
HETATM 12643 O  O     . HOH O 5 .   ? -13.932 25.390  -35.112  1.00 57.25  ? 809 HOH B O     1 
HETATM 12644 O  O     . HOH O 5 .   ? -36.480 27.117  -49.082  1.00 56.95  ? 810 HOH B O     1 
HETATM 12645 O  O     . HOH O 5 .   ? -26.406 16.760  -26.895  1.00 38.55  ? 811 HOH B O     1 
HETATM 12646 O  O     . HOH O 5 .   ? -39.718 30.640  -45.226  1.00 60.64  ? 812 HOH B O     1 
HETATM 12647 O  O     . HOH O 5 .   ? -26.836 26.034  -57.970  1.00 55.31  ? 813 HOH B O     1 
HETATM 12648 O  O     . HOH P 5 .   ? -9.171  4.190   -68.360  1.00 45.42  ? 701 HOH C O     1 
HETATM 12649 O  O     . HOH P 5 .   ? -8.074  -13.498 -57.863  1.00 56.42  ? 702 HOH C O     1 
HETATM 12650 O  O     . HOH P 5 .   ? -44.688 0.341   -59.849  1.00 55.70  ? 703 HOH C O     1 
HETATM 12651 O  O     . HOH P 5 .   ? -16.083 24.837  -72.836  1.00 41.87  ? 704 HOH C O     1 
HETATM 12652 O  O     . HOH P 5 .   ? -29.643 18.221  -53.948  1.00 38.97  ? 705 HOH C O     1 
HETATM 12653 O  O     . HOH P 5 .   ? -17.241 -18.276 -45.453  1.00 40.60  ? 706 HOH C O     1 
HETATM 12654 O  O     . HOH P 5 .   ? -22.001 5.533   -48.006  1.00 45.03  ? 707 HOH C O     1 
HETATM 12655 O  O     . HOH P 5 .   ? -29.497 0.754   -36.978  1.00 41.10  ? 708 HOH C O     1 
HETATM 12656 O  O     . HOH P 5 .   ? -2.604  -3.838  -58.791  1.00 36.01  ? 709 HOH C O     1 
HETATM 12657 O  O     . HOH P 5 .   ? -20.380 19.676  -86.402  1.00 51.40  ? 710 HOH C O     1 
HETATM 12658 O  O     . HOH P 5 .   ? -38.341 -13.575 -41.910  1.00 43.39  ? 711 HOH C O     1 
HETATM 12659 O  O     . HOH P 5 .   ? -7.060  -13.153 -45.165  1.00 48.88  ? 712 HOH C O     1 
HETATM 12660 O  O     . HOH P 5 .   ? -40.504 14.887  -44.901  1.00 50.49  ? 713 HOH C O     1 
HETATM 12661 O  O     . HOH P 5 .   ? -16.377 6.039   -42.055  1.00 38.44  ? 714 HOH C O     1 
HETATM 12662 O  O     . HOH P 5 .   ? -18.825 2.801   -43.628  1.00 42.56  ? 715 HOH C O     1 
HETATM 12663 O  O     . HOH P 5 .   ? -24.774 6.337   -42.503  1.00 35.34  ? 716 HOH C O     1 
HETATM 12664 O  O     . HOH P 5 .   ? -21.324 5.696   -51.313  1.00 38.46  ? 717 HOH C O     1 
HETATM 12665 O  O     . HOH P 5 .   ? -16.250 9.864   -39.584  1.00 36.27  ? 718 HOH C O     1 
HETATM 12666 O  O     . HOH P 5 .   ? -23.456 -16.172 -38.403  1.00 47.31  ? 719 HOH C O     1 
HETATM 12667 O  O     . HOH P 5 .   ? -16.887 2.319   -39.596  1.00 29.53  ? 720 HOH C O     1 
HETATM 12668 O  O     . HOH P 5 .   ? -29.458 3.370   -58.218  1.00 34.30  ? 721 HOH C O     1 
HETATM 12669 O  O     . HOH P 5 .   ? -32.062 -6.225  -39.414  1.00 46.07  ? 722 HOH C O     1 
HETATM 12670 O  O     . HOH P 5 .   ? -33.969 10.944  -40.781  1.00 55.13  ? 723 HOH C O     1 
HETATM 12671 O  O     . HOH P 5 .   ? -36.608 -12.887 -52.849  1.00 46.10  ? 724 HOH C O     1 
HETATM 12672 O  O     . HOH P 5 .   ? -31.261 -9.738  -38.645  1.00 50.15  ? 725 HOH C O     1 
HETATM 12673 O  O     . HOH P 5 .   ? -4.417  -6.388  -59.142  1.00 41.27  ? 726 HOH C O     1 
HETATM 12674 O  O     . HOH P 5 .   ? -22.130 4.582   -59.327  1.00 40.04  ? 727 HOH C O     1 
HETATM 12675 O  O     . HOH P 5 .   ? -30.748 -6.385  -83.900  1.00 46.05  ? 728 HOH C O     1 
HETATM 12676 O  O     . HOH P 5 .   ? -23.263 0.487   -68.145  1.00 55.03  ? 729 HOH C O     1 
HETATM 12677 O  O     . HOH P 5 .   ? -32.256 11.635  -57.270  1.00 35.99  ? 730 HOH C O     1 
HETATM 12678 O  O     . HOH P 5 .   ? -22.746 5.002   -45.568  1.00 33.99  ? 731 HOH C O     1 
HETATM 12679 O  O     . HOH P 5 .   ? -32.674 7.407   -57.533  1.00 38.93  ? 732 HOH C O     1 
HETATM 12680 O  O     . HOH P 5 .   ? -25.016 14.664  -45.956  1.00 38.21  ? 733 HOH C O     1 
HETATM 12681 O  O     . HOH P 5 .   ? -24.279 11.849  -58.956  1.00 40.88  ? 734 HOH C O     1 
HETATM 12682 O  O     . HOH P 5 .   ? -12.368 8.652   -88.350  1.00 71.12  ? 735 HOH C O     1 
HETATM 12683 O  O     . HOH P 5 .   ? -35.087 4.207   -67.925  1.00 43.92  ? 736 HOH C O     1 
HETATM 12684 O  O     . HOH P 5 .   ? -30.939 9.521   -56.570  1.00 38.40  ? 737 HOH C O     1 
HETATM 12685 O  O     . HOH P 5 .   ? -1.207  3.064   -79.578  1.00 51.61  ? 738 HOH C O     1 
HETATM 12686 O  O     . HOH P 5 .   ? 4.866   -3.930  -52.974  1.00 44.07  ? 739 HOH C O     1 
HETATM 12687 O  O     . HOH P 5 .   ? -35.645 6.669   -68.794  1.00 52.27  ? 740 HOH C O     1 
HETATM 12688 O  O     . HOH P 5 .   ? -21.915 12.058  -45.808  1.00 37.70  ? 741 HOH C O     1 
HETATM 12689 O  O     . HOH P 5 .   ? -41.080 2.168   -71.166  1.00 60.37  ? 742 HOH C O     1 
HETATM 12690 O  O     . HOH P 5 .   ? -3.088  -3.849  -68.167  1.00 46.04  ? 743 HOH C O     1 
HETATM 12691 O  O     . HOH P 5 .   ? -35.459 -7.907  -43.816  1.00 52.10  ? 744 HOH C O     1 
HETATM 12692 O  O     . HOH P 5 .   ? -30.259 6.021   -58.480  1.00 38.78  ? 745 HOH C O     1 
HETATM 12693 O  O     . HOH P 5 .   ? -33.727 8.570   -83.156  1.00 55.89  ? 746 HOH C O     1 
HETATM 12694 O  O     . HOH P 5 .   ? -19.212 3.192   -40.817  1.00 43.15  ? 747 HOH C O     1 
HETATM 12695 O  O     . HOH P 5 .   ? -28.833 8.200   -57.591  1.00 35.42  ? 748 HOH C O     1 
HETATM 12696 O  O     . HOH P 5 .   ? -15.025 -14.327 -65.631  1.00 51.73  ? 749 HOH C O     1 
HETATM 12697 O  O     . HOH P 5 .   ? -31.679 8.717   -41.985  1.00 40.32  ? 750 HOH C O     1 
HETATM 12698 O  O     . HOH P 5 .   ? -37.912 10.976  -60.941  1.00 41.01  ? 751 HOH C O     1 
HETATM 12699 O  O     . HOH P 5 .   ? -19.920 4.051   -37.989  1.00 37.79  ? 752 HOH C O     1 
HETATM 12700 O  O     . HOH P 5 .   ? -14.090 26.462  -84.730  1.00 62.24  ? 753 HOH C O     1 
HETATM 12701 O  O     . HOH P 5 .   ? -19.316 4.439   -62.115  1.00 41.19  ? 754 HOH C O     1 
HETATM 12702 O  O     . HOH P 5 .   ? -38.727 24.824  -66.301  1.00 53.83  ? 755 HOH C O     1 
HETATM 12703 O  O     . HOH P 5 .   ? -18.266 -10.942 -38.223  1.00 50.62  ? 756 HOH C O     1 
HETATM 12704 O  O     . HOH P 5 .   ? -34.667 -12.291 -62.851  1.00 66.27  ? 757 HOH C O     1 
HETATM 12705 O  O     . HOH P 5 .   ? -37.031 -18.943 -40.415  1.00 61.57  ? 758 HOH C O     1 
HETATM 12706 O  O     . HOH P 5 .   ? -2.049  6.581   -73.429  1.00 52.63  ? 759 HOH C O     1 
HETATM 12707 O  O     . HOH P 5 .   ? -9.999  21.779  -79.639  1.00 58.77  ? 760 HOH C O     1 
HETATM 12708 O  O     . HOH P 5 .   ? -41.087 12.710  -45.353  1.00 53.17  ? 761 HOH C O     1 
HETATM 12709 O  O     . HOH P 5 .   ? -43.137 -0.772  -50.384  1.00 45.29  ? 762 HOH C O     1 
HETATM 12710 O  O     . HOH P 5 .   ? -19.352 11.863  -59.163  1.00 47.56  ? 763 HOH C O     1 
HETATM 12711 O  O     . HOH P 5 .   ? -8.830  -19.304 -60.158  1.00 63.89  ? 764 HOH C O     1 
HETATM 12712 O  O     . HOH P 5 .   ? -33.852 24.860  -57.929  1.00 44.94  ? 765 HOH C O     1 
HETATM 12713 O  O     . HOH P 5 .   ? -20.558 9.987   -93.029  1.00 68.96  ? 766 HOH C O     1 
HETATM 12714 O  O     . HOH P 5 .   ? -22.760 11.873  -62.678  1.00 58.43  ? 767 HOH C O     1 
HETATM 12715 O  O     . HOH P 5 .   ? -24.704 16.800  -57.222  1.00 53.70  ? 768 HOH C O     1 
HETATM 12716 O  O     . HOH P 5 .   ? -1.162  -7.443  -50.990  1.00 65.76  ? 769 HOH C O     1 
HETATM 12717 O  O     . HOH P 5 .   ? -13.723 -22.555 -60.280  1.00 70.39  ? 770 HOH C O     1 
# 
