data_8S7S
# 
_entry.id   8S7S 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8S7S         pdb_00008s7s 10.2210/pdb8s7s/pdb 
WWPDB D_1292137020 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2025-01-15 
2 'Structure model' 1 1 2025-01-22 
3 'Structure model' 1 2 2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 3 'Structure model' citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
2 2 'Structure model' '_citation.title'                   
3 3 'Structure model' '_citation.journal_volume'          
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8S7S 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-04 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              andrea.mattevi@unipv.it 
_pdbx_contact_author.name_first         Mattevi 
_pdbx_contact_author.name_last          Andrea 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-9523-7128 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Guerriere, T.B.' 1 0009-0003-3232-6822 
'Mattevi, A.'     2 0000-0002-9523-7128 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Catalysis' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2155-5435 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                1046 
_citation.page_last                 1060 
_citation.title                     
'Dehydrogenase versus oxidase function: the interplay between substrate binding and flavin microenvironment.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acscatal.4c05944 
_citation.pdbx_database_id_PubMed   39781101 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Guerriere, T.B.' 1  ? 
primary 'Vancheri, A.'    2  ? 
primary 'Ricotti, I.'     3  ? 
primary 'Serapian, S.A.'  4  ? 
primary 'Eggerichs, D.'   5  ? 
primary 'Tischler, D.'    6  ? 
primary 'Colombo, G.'     7  ? 
primary 'Mascotti, M.L.'  8  ? 
primary 'Fraaije, M.W.'   9  ? 
primary 'Mattevi, A.'     10 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man Oxidoreductase                58205.738 3   ? ? ? ? 
2 non-polymer syn 'FLAVIN-ADENINE DINUCLEOTIDE' 785.550   3   ? ? ? ? 
3 water       nat water                         18.015    242 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAAPLPEGVSAEAMSSALDRFARIVGADWVFTEDKITPYEDPYTISNDETEHRPYAAVAPASTEEVQEIVRVANEFGVPL
WPVSRGKNFAYGGAAPVMSGTVVLDMNRMNRILEVNEEFGYALVEPGVSYFELYDYIQEKGLKLWIDVPDGGWGSVVGNA
LDHGIGYTPYGDHFAMQCGMEVVLPNGEVVRTGMGAMPGNNTWQLFKYGYGPYVDGIFSQSNFGVVTKMGIWLMPEPAGY
RPYLITFENEDDIETVTERLRPLKVAGVIQNGATVRSLVLDAAITRTKSQYYDGDGPIPPSVAKTMMADLDLGMWNFCGA
LYGPPPVMDTLWTAIRDSFADIPGVKFYFPEDRRHKVDLLLHRAETMKGVPKLTEFNFLNWDGGGGHVGFSPVSPITGKD
AIKQYNMVSSRVREYGFDYMGLLAIGWRDLHHVTVIVYDKTDPDERKKLDELFNILVDEAAAEGYGEYRTHIRYMDRIAK
TYSWNDNALWKMHETIKDALDPNGILAPGKSGIWGKNRRKA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAAPLPEGVSAEAMSSALDRFARIVGADWVFTEDKITPYEDPYTISNDETEHRPYAAVAPASTEEVQEIVRVANEFGVPL
WPVSRGKNFAYGGAAPVMSGTVVLDMNRMNRILEVNEEFGYALVEPGVSYFELYDYIQEKGLKLWIDVPDGGWGSVVGNA
LDHGIGYTPYGDHFAMQCGMEVVLPNGEVVRTGMGAMPGNNTWQLFKYGYGPYVDGIFSQSNFGVVTKMGIWLMPEPAGY
RPYLITFENEDDIETVTERLRPLKVAGVIQNGATVRSLVLDAAITRTKSQYYDGDGPIPPSVAKTMMADLDLGMWNFCGA
LYGPPPVMDTLWTAIRDSFADIPGVKFYFPEDRRHKVDLLLHRAETMKGVPKLTEFNFLNWDGGGGHVGFSPVSPITGKD
AIKQYNMVSSRVREYGFDYMGLLAIGWRDLHHVTVIVYDKTDPDERKKLDELFNILVDEAAAEGYGEYRTHIRYMDRIAK
TYSWNDNALWKMHETIKDALDPNGILAPGKSGIWGKNRRKA
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'FLAVIN-ADENINE DINUCLEOTIDE' FAD 
3 water                         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   ALA n 
1 4   PRO n 
1 5   LEU n 
1 6   PRO n 
1 7   GLU n 
1 8   GLY n 
1 9   VAL n 
1 10  SER n 
1 11  ALA n 
1 12  GLU n 
1 13  ALA n 
1 14  MET n 
1 15  SER n 
1 16  SER n 
1 17  ALA n 
1 18  LEU n 
1 19  ASP n 
1 20  ARG n 
1 21  PHE n 
1 22  ALA n 
1 23  ARG n 
1 24  ILE n 
1 25  VAL n 
1 26  GLY n 
1 27  ALA n 
1 28  ASP n 
1 29  TRP n 
1 30  VAL n 
1 31  PHE n 
1 32  THR n 
1 33  GLU n 
1 34  ASP n 
1 35  LYS n 
1 36  ILE n 
1 37  THR n 
1 38  PRO n 
1 39  TYR n 
1 40  GLU n 
1 41  ASP n 
1 42  PRO n 
1 43  TYR n 
1 44  THR n 
1 45  ILE n 
1 46  SER n 
1 47  ASN n 
1 48  ASP n 
1 49  GLU n 
1 50  THR n 
1 51  GLU n 
1 52  HIS n 
1 53  ARG n 
1 54  PRO n 
1 55  TYR n 
1 56  ALA n 
1 57  ALA n 
1 58  VAL n 
1 59  ALA n 
1 60  PRO n 
1 61  ALA n 
1 62  SER n 
1 63  THR n 
1 64  GLU n 
1 65  GLU n 
1 66  VAL n 
1 67  GLN n 
1 68  GLU n 
1 69  ILE n 
1 70  VAL n 
1 71  ARG n 
1 72  VAL n 
1 73  ALA n 
1 74  ASN n 
1 75  GLU n 
1 76  PHE n 
1 77  GLY n 
1 78  VAL n 
1 79  PRO n 
1 80  LEU n 
1 81  TRP n 
1 82  PRO n 
1 83  VAL n 
1 84  SER n 
1 85  ARG n 
1 86  GLY n 
1 87  LYS n 
1 88  ASN n 
1 89  PHE n 
1 90  ALA n 
1 91  TYR n 
1 92  GLY n 
1 93  GLY n 
1 94  ALA n 
1 95  ALA n 
1 96  PRO n 
1 97  VAL n 
1 98  MET n 
1 99  SER n 
1 100 GLY n 
1 101 THR n 
1 102 VAL n 
1 103 VAL n 
1 104 LEU n 
1 105 ASP n 
1 106 MET n 
1 107 ASN n 
1 108 ARG n 
1 109 MET n 
1 110 ASN n 
1 111 ARG n 
1 112 ILE n 
1 113 LEU n 
1 114 GLU n 
1 115 VAL n 
1 116 ASN n 
1 117 GLU n 
1 118 GLU n 
1 119 PHE n 
1 120 GLY n 
1 121 TYR n 
1 122 ALA n 
1 123 LEU n 
1 124 VAL n 
1 125 GLU n 
1 126 PRO n 
1 127 GLY n 
1 128 VAL n 
1 129 SER n 
1 130 TYR n 
1 131 PHE n 
1 132 GLU n 
1 133 LEU n 
1 134 TYR n 
1 135 ASP n 
1 136 TYR n 
1 137 ILE n 
1 138 GLN n 
1 139 GLU n 
1 140 LYS n 
1 141 GLY n 
1 142 LEU n 
1 143 LYS n 
1 144 LEU n 
1 145 TRP n 
1 146 ILE n 
1 147 ASP n 
1 148 VAL n 
1 149 PRO n 
1 150 ASP n 
1 151 GLY n 
1 152 GLY n 
1 153 TRP n 
1 154 GLY n 
1 155 SER n 
1 156 VAL n 
1 157 VAL n 
1 158 GLY n 
1 159 ASN n 
1 160 ALA n 
1 161 LEU n 
1 162 ASP n 
1 163 HIS n 
1 164 GLY n 
1 165 ILE n 
1 166 GLY n 
1 167 TYR n 
1 168 THR n 
1 169 PRO n 
1 170 TYR n 
1 171 GLY n 
1 172 ASP n 
1 173 HIS n 
1 174 PHE n 
1 175 ALA n 
1 176 MET n 
1 177 GLN n 
1 178 CYS n 
1 179 GLY n 
1 180 MET n 
1 181 GLU n 
1 182 VAL n 
1 183 VAL n 
1 184 LEU n 
1 185 PRO n 
1 186 ASN n 
1 187 GLY n 
1 188 GLU n 
1 189 VAL n 
1 190 VAL n 
1 191 ARG n 
1 192 THR n 
1 193 GLY n 
1 194 MET n 
1 195 GLY n 
1 196 ALA n 
1 197 MET n 
1 198 PRO n 
1 199 GLY n 
1 200 ASN n 
1 201 ASN n 
1 202 THR n 
1 203 TRP n 
1 204 GLN n 
1 205 LEU n 
1 206 PHE n 
1 207 LYS n 
1 208 TYR n 
1 209 GLY n 
1 210 TYR n 
1 211 GLY n 
1 212 PRO n 
1 213 TYR n 
1 214 VAL n 
1 215 ASP n 
1 216 GLY n 
1 217 ILE n 
1 218 PHE n 
1 219 SER n 
1 220 GLN n 
1 221 SER n 
1 222 ASN n 
1 223 PHE n 
1 224 GLY n 
1 225 VAL n 
1 226 VAL n 
1 227 THR n 
1 228 LYS n 
1 229 MET n 
1 230 GLY n 
1 231 ILE n 
1 232 TRP n 
1 233 LEU n 
1 234 MET n 
1 235 PRO n 
1 236 GLU n 
1 237 PRO n 
1 238 ALA n 
1 239 GLY n 
1 240 TYR n 
1 241 ARG n 
1 242 PRO n 
1 243 TYR n 
1 244 LEU n 
1 245 ILE n 
1 246 THR n 
1 247 PHE n 
1 248 GLU n 
1 249 ASN n 
1 250 GLU n 
1 251 ASP n 
1 252 ASP n 
1 253 ILE n 
1 254 GLU n 
1 255 THR n 
1 256 VAL n 
1 257 THR n 
1 258 GLU n 
1 259 ARG n 
1 260 LEU n 
1 261 ARG n 
1 262 PRO n 
1 263 LEU n 
1 264 LYS n 
1 265 VAL n 
1 266 ALA n 
1 267 GLY n 
1 268 VAL n 
1 269 ILE n 
1 270 GLN n 
1 271 ASN n 
1 272 GLY n 
1 273 ALA n 
1 274 THR n 
1 275 VAL n 
1 276 ARG n 
1 277 SER n 
1 278 LEU n 
1 279 VAL n 
1 280 LEU n 
1 281 ASP n 
1 282 ALA n 
1 283 ALA n 
1 284 ILE n 
1 285 THR n 
1 286 ARG n 
1 287 THR n 
1 288 LYS n 
1 289 SER n 
1 290 GLN n 
1 291 TYR n 
1 292 TYR n 
1 293 ASP n 
1 294 GLY n 
1 295 ASP n 
1 296 GLY n 
1 297 PRO n 
1 298 ILE n 
1 299 PRO n 
1 300 PRO n 
1 301 SER n 
1 302 VAL n 
1 303 ALA n 
1 304 LYS n 
1 305 THR n 
1 306 MET n 
1 307 MET n 
1 308 ALA n 
1 309 ASP n 
1 310 LEU n 
1 311 ASP n 
1 312 LEU n 
1 313 GLY n 
1 314 MET n 
1 315 TRP n 
1 316 ASN n 
1 317 PHE n 
1 318 CYS n 
1 319 GLY n 
1 320 ALA n 
1 321 LEU n 
1 322 TYR n 
1 323 GLY n 
1 324 PRO n 
1 325 PRO n 
1 326 PRO n 
1 327 VAL n 
1 328 MET n 
1 329 ASP n 
1 330 THR n 
1 331 LEU n 
1 332 TRP n 
1 333 THR n 
1 334 ALA n 
1 335 ILE n 
1 336 ARG n 
1 337 ASP n 
1 338 SER n 
1 339 PHE n 
1 340 ALA n 
1 341 ASP n 
1 342 ILE n 
1 343 PRO n 
1 344 GLY n 
1 345 VAL n 
1 346 LYS n 
1 347 PHE n 
1 348 TYR n 
1 349 PHE n 
1 350 PRO n 
1 351 GLU n 
1 352 ASP n 
1 353 ARG n 
1 354 ARG n 
1 355 HIS n 
1 356 LYS n 
1 357 VAL n 
1 358 ASP n 
1 359 LEU n 
1 360 LEU n 
1 361 LEU n 
1 362 HIS n 
1 363 ARG n 
1 364 ALA n 
1 365 GLU n 
1 366 THR n 
1 367 MET n 
1 368 LYS n 
1 369 GLY n 
1 370 VAL n 
1 371 PRO n 
1 372 LYS n 
1 373 LEU n 
1 374 THR n 
1 375 GLU n 
1 376 PHE n 
1 377 ASN n 
1 378 PHE n 
1 379 LEU n 
1 380 ASN n 
1 381 TRP n 
1 382 ASP n 
1 383 GLY n 
1 384 GLY n 
1 385 GLY n 
1 386 GLY n 
1 387 HIS n 
1 388 VAL n 
1 389 GLY n 
1 390 PHE n 
1 391 SER n 
1 392 PRO n 
1 393 VAL n 
1 394 SER n 
1 395 PRO n 
1 396 ILE n 
1 397 THR n 
1 398 GLY n 
1 399 LYS n 
1 400 ASP n 
1 401 ALA n 
1 402 ILE n 
1 403 LYS n 
1 404 GLN n 
1 405 TYR n 
1 406 ASN n 
1 407 MET n 
1 408 VAL n 
1 409 SER n 
1 410 SER n 
1 411 ARG n 
1 412 VAL n 
1 413 ARG n 
1 414 GLU n 
1 415 TYR n 
1 416 GLY n 
1 417 PHE n 
1 418 ASP n 
1 419 TYR n 
1 420 MET n 
1 421 GLY n 
1 422 LEU n 
1 423 LEU n 
1 424 ALA n 
1 425 ILE n 
1 426 GLY n 
1 427 TRP n 
1 428 ARG n 
1 429 ASP n 
1 430 LEU n 
1 431 HIS n 
1 432 HIS n 
1 433 VAL n 
1 434 THR n 
1 435 VAL n 
1 436 ILE n 
1 437 VAL n 
1 438 TYR n 
1 439 ASP n 
1 440 LYS n 
1 441 THR n 
1 442 ASP n 
1 443 PRO n 
1 444 ASP n 
1 445 GLU n 
1 446 ARG n 
1 447 LYS n 
1 448 LYS n 
1 449 LEU n 
1 450 ASP n 
1 451 GLU n 
1 452 LEU n 
1 453 PHE n 
1 454 ASN n 
1 455 ILE n 
1 456 LEU n 
1 457 VAL n 
1 458 ASP n 
1 459 GLU n 
1 460 ALA n 
1 461 ALA n 
1 462 ALA n 
1 463 GLU n 
1 464 GLY n 
1 465 TYR n 
1 466 GLY n 
1 467 GLU n 
1 468 TYR n 
1 469 ARG n 
1 470 THR n 
1 471 HIS n 
1 472 ILE n 
1 473 ARG n 
1 474 TYR n 
1 475 MET n 
1 476 ASP n 
1 477 ARG n 
1 478 ILE n 
1 479 ALA n 
1 480 LYS n 
1 481 THR n 
1 482 TYR n 
1 483 SER n 
1 484 TRP n 
1 485 ASN n 
1 486 ASP n 
1 487 ASN n 
1 488 ALA n 
1 489 LEU n 
1 490 TRP n 
1 491 LYS n 
1 492 MET n 
1 493 HIS n 
1 494 GLU n 
1 495 THR n 
1 496 ILE n 
1 497 LYS n 
1 498 ASP n 
1 499 ALA n 
1 500 LEU n 
1 501 ASP n 
1 502 PRO n 
1 503 ASN n 
1 504 GLY n 
1 505 ILE n 
1 506 LEU n 
1 507 ALA n 
1 508 PRO n 
1 509 GLY n 
1 510 LYS n 
1 511 SER n 
1 512 GLY n 
1 513 ILE n 
1 514 TRP n 
1 515 GLY n 
1 516 LYS n 
1 517 ASN n 
1 518 ARG n 
1 519 ARG n 
1 520 LYS n 
1 521 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   521 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 CW354_13745 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Marinicaulis flavus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2058213 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                       ? 'C3 H7 N O2'        89.093  
ARG 'L-peptide linking' y ARGININE                      ? 'C6 H15 N4 O2 1'    175.209 
ASN 'L-peptide linking' y ASPARAGINE                    ? 'C4 H8 N2 O3'       132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'               ? 'C4 H7 N O4'        133.103 
CYS 'L-peptide linking' y CYSTEINE                      ? 'C3 H7 N O2 S'      121.158 
FAD non-polymer         . 'FLAVIN-ADENINE DINUCLEOTIDE' ? 'C27 H33 N9 O15 P2' 785.550 
GLN 'L-peptide linking' y GLUTAMINE                     ? 'C5 H10 N2 O3'      146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'               ? 'C5 H9 N O4'        147.129 
GLY 'peptide linking'   y GLYCINE                       ? 'C2 H5 N O2'        75.067  
HIS 'L-peptide linking' y HISTIDINE                     ? 'C6 H10 N3 O2 1'    156.162 
HOH non-polymer         . WATER                         ? 'H2 O'              18.015  
ILE 'L-peptide linking' y ISOLEUCINE                    ? 'C6 H13 N O2'       131.173 
LEU 'L-peptide linking' y LEUCINE                       ? 'C6 H13 N O2'       131.173 
LYS 'L-peptide linking' y LYSINE                        ? 'C6 H15 N2 O2 1'    147.195 
MET 'L-peptide linking' y METHIONINE                    ? 'C5 H11 N O2 S'     149.211 
PHE 'L-peptide linking' y PHENYLALANINE                 ? 'C9 H11 N O2'       165.189 
PRO 'L-peptide linking' y PROLINE                       ? 'C5 H9 N O2'        115.130 
SER 'L-peptide linking' y SERINE                        ? 'C3 H7 N O3'        105.093 
THR 'L-peptide linking' y THREONINE                     ? 'C4 H9 N O3'        119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                    ? 'C11 H12 N2 O2'     204.225 
TYR 'L-peptide linking' y TYROSINE                      ? 'C9 H11 N O3'       181.189 
VAL 'L-peptide linking' y VALINE                        ? 'C5 H11 N O2'       117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   2   ALA ALA A . n 
A 1 3   ALA 3   3   3   ALA ALA A . n 
A 1 4   PRO 4   4   4   PRO PRO A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   PRO 6   6   6   PRO PRO A . n 
A 1 7   GLU 7   7   7   GLU GLU A . n 
A 1 8   GLY 8   8   8   GLY GLY A . n 
A 1 9   VAL 9   9   9   VAL VAL A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  GLU 12  12  12  GLU GLU A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  MET 14  14  14  MET MET A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  SER 16  16  16  SER SER A . n 
A 1 17  ALA 17  17  17  ALA ALA A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  ASP 19  19  19  ASP ASP A . n 
A 1 20  ARG 20  20  20  ARG ARG A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  ALA 22  22  22  ALA ALA A . n 
A 1 23  ARG 23  23  23  ARG ARG A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  ASP 28  28  28  ASP ASP A . n 
A 1 29  TRP 29  29  29  TRP TRP A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  PHE 31  31  31  PHE PHE A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  LYS 35  35  35  LYS LYS A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  THR 37  37  37  THR THR A . n 
A 1 38  PRO 38  38  38  PRO PRO A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  GLU 40  40  40  GLU GLU A . n 
A 1 41  ASP 41  41  41  ASP ASP A . n 
A 1 42  PRO 42  42  42  PRO PRO A . n 
A 1 43  TYR 43  43  43  TYR TYR A . n 
A 1 44  THR 44  44  44  THR THR A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  ASP 48  48  48  ASP ASP A . n 
A 1 49  GLU 49  49  49  GLU GLU A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  HIS 52  52  52  HIS HIS A . n 
A 1 53  ARG 53  53  53  ARG ARG A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  VAL 58  58  58  VAL VAL A . n 
A 1 59  ALA 59  59  59  ALA ALA A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  ALA 61  61  61  ALA ALA A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  GLU 64  64  64  GLU GLU A . n 
A 1 65  GLU 65  65  65  GLU GLU A . n 
A 1 66  VAL 66  66  66  VAL VAL A . n 
A 1 67  GLN 67  67  67  GLN GLN A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  VAL 70  70  70  VAL VAL A . n 
A 1 71  ARG 71  71  71  ARG ARG A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  ALA 73  73  73  ALA ALA A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  PHE 76  76  76  PHE PHE A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  VAL 78  78  78  VAL VAL A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  TRP 81  81  81  TRP TRP A . n 
A 1 82  PRO 82  82  82  PRO PRO A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  ARG 85  85  85  ARG ARG A . n 
A 1 86  GLY 86  86  86  GLY GLY A . n 
A 1 87  LYS 87  87  87  LYS LYS A . n 
A 1 88  ASN 88  88  88  ASN ASN A . n 
A 1 89  PHE 89  89  89  PHE PHE A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  TYR 91  91  91  TYR TYR A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  ALA 94  94  94  ALA ALA A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  VAL 97  97  97  VAL VAL A . n 
A 1 98  MET 98  98  98  MET MET A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 VAL 103 103 103 VAL VAL A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 MET 106 106 106 MET MET A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 MET 109 109 109 MET MET A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 ILE 112 112 112 ILE ILE A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 GLU 114 114 114 GLU GLU A . n 
A 1 115 VAL 115 115 115 VAL VAL A . n 
A 1 116 ASN 116 116 116 ASN ASN A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 PHE 119 119 119 PHE PHE A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 TYR 121 121 121 TYR TYR A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 PRO 126 126 126 PRO PRO A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 SER 129 129 129 SER SER A . n 
A 1 130 TYR 130 130 130 TYR TYR A . n 
A 1 131 PHE 131 131 131 PHE PHE A . n 
A 1 132 GLU 132 132 132 GLU GLU A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 TYR 134 134 134 TYR TYR A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 TYR 136 136 136 TYR TYR A . n 
A 1 137 ILE 137 137 137 ILE ILE A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 GLY 141 141 141 GLY GLY A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 LYS 143 143 143 LYS LYS A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 TRP 145 145 145 TRP TRP A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 PRO 149 149 149 PRO PRO A . n 
A 1 150 ASP 150 150 150 ASP ASP A . n 
A 1 151 GLY 151 151 151 GLY GLY A . n 
A 1 152 GLY 152 152 152 GLY GLY A . n 
A 1 153 TRP 153 153 153 TRP TRP A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 ASN 159 159 159 ASN ASN A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 ASP 162 162 162 ASP ASP A . n 
A 1 163 HIS 163 163 163 HIS HIS A . n 
A 1 164 GLY 164 164 164 GLY GLY A . n 
A 1 165 ILE 165 165 165 ILE ILE A . n 
A 1 166 GLY 166 166 166 GLY GLY A . n 
A 1 167 TYR 167 167 167 TYR TYR A . n 
A 1 168 THR 168 168 168 THR THR A . n 
A 1 169 PRO 169 169 169 PRO PRO A . n 
A 1 170 TYR 170 170 170 TYR TYR A . n 
A 1 171 GLY 171 171 171 GLY GLY A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 HIS 173 173 173 HIS HIS A . n 
A 1 174 PHE 174 174 174 PHE PHE A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 CYS 178 178 178 CYS CYS A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 MET 180 180 180 MET MET A . n 
A 1 181 GLU 181 181 181 GLU GLU A . n 
A 1 182 VAL 182 182 182 VAL VAL A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 PRO 185 185 185 PRO PRO A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 GLU 188 188 188 GLU GLU A . n 
A 1 189 VAL 189 189 189 VAL VAL A . n 
A 1 190 VAL 190 190 190 VAL VAL A . n 
A 1 191 ARG 191 191 191 ARG ARG A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 MET 194 194 194 MET MET A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 ALA 196 196 196 ALA ALA A . n 
A 1 197 MET 197 197 197 MET MET A . n 
A 1 198 PRO 198 198 198 PRO PRO A . n 
A 1 199 GLY 199 199 199 GLY GLY A . n 
A 1 200 ASN 200 200 200 ASN ASN A . n 
A 1 201 ASN 201 201 201 ASN ASN A . n 
A 1 202 THR 202 202 202 THR THR A . n 
A 1 203 TRP 203 203 203 TRP TRP A . n 
A 1 204 GLN 204 204 204 GLN GLN A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 PHE 206 206 206 PHE PHE A . n 
A 1 207 LYS 207 207 207 LYS LYS A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 TYR 210 210 210 TYR TYR A . n 
A 1 211 GLY 211 211 211 GLY GLY A . n 
A 1 212 PRO 212 212 212 PRO PRO A . n 
A 1 213 TYR 213 213 213 TYR TYR A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 ASP 215 215 215 ASP ASP A . n 
A 1 216 GLY 216 216 216 GLY GLY A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 PHE 218 218 218 PHE PHE A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 GLN 220 220 220 GLN GLN A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 ASN 222 222 222 ASN ASN A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 THR 227 227 227 THR THR A . n 
A 1 228 LYS 228 228 228 LYS LYS A . n 
A 1 229 MET 229 229 229 MET MET A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 ILE 231 231 231 ILE ILE A . n 
A 1 232 TRP 232 232 232 TRP TRP A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 MET 234 234 234 MET MET A . n 
A 1 235 PRO 235 235 235 PRO PRO A . n 
A 1 236 GLU 236 236 236 GLU GLU A . n 
A 1 237 PRO 237 237 237 PRO PRO A . n 
A 1 238 ALA 238 238 238 ALA ALA A . n 
A 1 239 GLY 239 239 239 GLY GLY A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 ARG 241 241 241 ARG ARG A . n 
A 1 242 PRO 242 242 242 PRO PRO A . n 
A 1 243 TYR 243 243 243 TYR TYR A . n 
A 1 244 LEU 244 244 244 LEU LEU A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 THR 246 246 246 THR THR A . n 
A 1 247 PHE 247 247 247 PHE PHE A . n 
A 1 248 GLU 248 248 248 GLU GLU A . n 
A 1 249 ASN 249 249 249 ASN ASN A . n 
A 1 250 GLU 250 250 250 GLU GLU A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 ASP 252 252 252 ASP ASP A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 GLU 254 254 254 GLU GLU A . n 
A 1 255 THR 255 255 255 THR THR A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 ARG 259 259 259 ARG ARG A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 ARG 261 261 261 ARG ARG A . n 
A 1 262 PRO 262 262 262 PRO PRO A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 LYS 264 264 264 LYS LYS A . n 
A 1 265 VAL 265 265 265 VAL VAL A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 GLY 267 267 267 GLY GLY A . n 
A 1 268 VAL 268 268 268 VAL VAL A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 GLN 270 270 270 GLN GLN A . n 
A 1 271 ASN 271 271 271 ASN ASN A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 THR 274 274 274 THR THR A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 SER 277 277 277 SER SER A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 VAL 279 279 279 VAL VAL A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 ASP 281 281 281 ASP ASP A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 ILE 284 284 284 ILE ILE A . n 
A 1 285 THR 285 285 285 THR THR A . n 
A 1 286 ARG 286 286 286 ARG ARG A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 LYS 288 288 288 LYS LYS A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 GLN 290 290 290 GLN GLN A . n 
A 1 291 TYR 291 291 291 TYR TYR A . n 
A 1 292 TYR 292 292 292 TYR TYR A . n 
A 1 293 ASP 293 293 293 ASP ASP A . n 
A 1 294 GLY 294 294 294 GLY GLY A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 PRO 297 297 297 PRO PRO A . n 
A 1 298 ILE 298 298 298 ILE ILE A . n 
A 1 299 PRO 299 299 299 PRO PRO A . n 
A 1 300 PRO 300 300 300 PRO PRO A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 VAL 302 302 302 VAL VAL A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 LYS 304 304 304 LYS LYS A . n 
A 1 305 THR 305 305 305 THR THR A . n 
A 1 306 MET 306 306 306 MET MET A . n 
A 1 307 MET 307 307 307 MET MET A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 ASP 309 309 309 ASP ASP A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ASP 311 311 311 ASP ASP A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 GLY 313 313 313 GLY GLY A . n 
A 1 314 MET 314 314 314 MET MET A . n 
A 1 315 TRP 315 315 315 TRP TRP A . n 
A 1 316 ASN 316 316 316 ASN ASN A . n 
A 1 317 PHE 317 317 317 PHE PHE A . n 
A 1 318 CYS 318 318 318 CYS CYS A . n 
A 1 319 GLY 319 319 319 GLY GLY A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 TYR 322 322 322 TYR TYR A . n 
A 1 323 GLY 323 323 323 GLY GLY A . n 
A 1 324 PRO 324 324 324 PRO PRO A . n 
A 1 325 PRO 325 325 325 PRO PRO A . n 
A 1 326 PRO 326 326 326 PRO PRO A . n 
A 1 327 VAL 327 327 327 VAL VAL A . n 
A 1 328 MET 328 328 328 MET MET A . n 
A 1 329 ASP 329 329 329 ASP ASP A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 TRP 332 332 332 TRP TRP A . n 
A 1 333 THR 333 333 333 THR THR A . n 
A 1 334 ALA 334 334 334 ALA ALA A . n 
A 1 335 ILE 335 335 335 ILE ILE A . n 
A 1 336 ARG 336 336 336 ARG ARG A . n 
A 1 337 ASP 337 337 337 ASP ASP A . n 
A 1 338 SER 338 338 338 SER SER A . n 
A 1 339 PHE 339 339 339 PHE PHE A . n 
A 1 340 ALA 340 340 340 ALA ALA A . n 
A 1 341 ASP 341 341 341 ASP ASP A . n 
A 1 342 ILE 342 342 342 ILE ILE A . n 
A 1 343 PRO 343 343 343 PRO PRO A . n 
A 1 344 GLY 344 344 344 GLY GLY A . n 
A 1 345 VAL 345 345 345 VAL VAL A . n 
A 1 346 LYS 346 346 346 LYS LYS A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 TYR 348 348 348 TYR TYR A . n 
A 1 349 PHE 349 349 349 PHE PHE A . n 
A 1 350 PRO 350 350 350 PRO PRO A . n 
A 1 351 GLU 351 351 351 GLU GLU A . n 
A 1 352 ASP 352 352 352 ASP ASP A . n 
A 1 353 ARG 353 353 353 ARG ARG A . n 
A 1 354 ARG 354 354 354 ARG ARG A . n 
A 1 355 HIS 355 355 355 HIS HIS A . n 
A 1 356 LYS 356 356 356 LYS LYS A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 ASP 358 358 358 ASP ASP A . n 
A 1 359 LEU 359 359 359 LEU LEU A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 HIS 362 362 362 HIS HIS A . n 
A 1 363 ARG 363 363 363 ARG ARG A . n 
A 1 364 ALA 364 364 364 ALA ALA A . n 
A 1 365 GLU 365 365 365 GLU GLU A . n 
A 1 366 THR 366 366 366 THR THR A . n 
A 1 367 MET 367 367 367 MET MET A . n 
A 1 368 LYS 368 368 368 LYS LYS A . n 
A 1 369 GLY 369 369 369 GLY GLY A . n 
A 1 370 VAL 370 370 370 VAL VAL A . n 
A 1 371 PRO 371 371 371 PRO PRO A . n 
A 1 372 LYS 372 372 372 LYS LYS A . n 
A 1 373 LEU 373 373 373 LEU LEU A . n 
A 1 374 THR 374 374 374 THR THR A . n 
A 1 375 GLU 375 375 375 GLU GLU A . n 
A 1 376 PHE 376 376 376 PHE PHE A . n 
A 1 377 ASN 377 377 377 ASN ASN A . n 
A 1 378 PHE 378 378 378 PHE PHE A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 ASN 380 380 380 ASN ASN A . n 
A 1 381 TRP 381 381 381 TRP TRP A . n 
A 1 382 ASP 382 382 382 ASP ASP A . n 
A 1 383 GLY 383 383 383 GLY GLY A . n 
A 1 384 GLY 384 384 384 GLY GLY A . n 
A 1 385 GLY 385 385 385 GLY GLY A . n 
A 1 386 GLY 386 386 386 GLY GLY A . n 
A 1 387 HIS 387 387 387 HIS HIS A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 GLY 389 389 389 GLY GLY A . n 
A 1 390 PHE 390 390 390 PHE PHE A . n 
A 1 391 SER 391 391 391 SER SER A . n 
A 1 392 PRO 392 392 392 PRO PRO A . n 
A 1 393 VAL 393 393 393 VAL VAL A . n 
A 1 394 SER 394 394 394 SER SER A . n 
A 1 395 PRO 395 395 395 PRO PRO A . n 
A 1 396 ILE 396 396 396 ILE ILE A . n 
A 1 397 THR 397 397 397 THR THR A . n 
A 1 398 GLY 398 398 398 GLY GLY A . n 
A 1 399 LYS 399 399 399 LYS LYS A . n 
A 1 400 ASP 400 400 400 ASP ASP A . n 
A 1 401 ALA 401 401 401 ALA ALA A . n 
A 1 402 ILE 402 402 402 ILE ILE A . n 
A 1 403 LYS 403 403 403 LYS LYS A . n 
A 1 404 GLN 404 404 404 GLN GLN A . n 
A 1 405 TYR 405 405 405 TYR TYR A . n 
A 1 406 ASN 406 406 406 ASN ASN A . n 
A 1 407 MET 407 407 407 MET MET A . n 
A 1 408 VAL 408 408 408 VAL VAL A . n 
A 1 409 SER 409 409 409 SER SER A . n 
A 1 410 SER 410 410 410 SER SER A . n 
A 1 411 ARG 411 411 411 ARG ARG A . n 
A 1 412 VAL 412 412 412 VAL VAL A . n 
A 1 413 ARG 413 413 413 ARG ARG A . n 
A 1 414 GLU 414 414 414 GLU GLU A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 GLY 416 416 416 GLY GLY A . n 
A 1 417 PHE 417 417 417 PHE PHE A . n 
A 1 418 ASP 418 418 418 ASP ASP A . n 
A 1 419 TYR 419 419 419 TYR TYR A . n 
A 1 420 MET 420 420 420 MET MET A . n 
A 1 421 GLY 421 421 421 GLY GLY A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 LEU 423 423 423 LEU LEU A . n 
A 1 424 ALA 424 424 424 ALA ALA A . n 
A 1 425 ILE 425 425 425 ILE ILE A . n 
A 1 426 GLY 426 426 426 GLY GLY A . n 
A 1 427 TRP 427 427 427 TRP TRP A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 ASP 429 429 429 ASP ASP A . n 
A 1 430 LEU 430 430 430 LEU LEU A . n 
A 1 431 HIS 431 431 431 HIS HIS A . n 
A 1 432 HIS 432 432 432 HIS HIS A . n 
A 1 433 VAL 433 433 433 VAL VAL A . n 
A 1 434 THR 434 434 434 THR THR A . n 
A 1 435 VAL 435 435 435 VAL VAL A . n 
A 1 436 ILE 436 436 436 ILE ILE A . n 
A 1 437 VAL 437 437 437 VAL VAL A . n 
A 1 438 TYR 438 438 438 TYR TYR A . n 
A 1 439 ASP 439 439 439 ASP ASP A . n 
A 1 440 LYS 440 440 440 LYS LYS A . n 
A 1 441 THR 441 441 441 THR THR A . n 
A 1 442 ASP 442 442 442 ASP ASP A . n 
A 1 443 PRO 443 443 443 PRO PRO A . n 
A 1 444 ASP 444 444 444 ASP ASP A . n 
A 1 445 GLU 445 445 445 GLU GLU A . n 
A 1 446 ARG 446 446 446 ARG ARG A . n 
A 1 447 LYS 447 447 447 LYS LYS A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 ASP 450 450 450 ASP ASP A . n 
A 1 451 GLU 451 451 451 GLU GLU A . n 
A 1 452 LEU 452 452 452 LEU LEU A . n 
A 1 453 PHE 453 453 453 PHE PHE A . n 
A 1 454 ASN 454 454 454 ASN ASN A . n 
A 1 455 ILE 455 455 455 ILE ILE A . n 
A 1 456 LEU 456 456 456 LEU LEU A . n 
A 1 457 VAL 457 457 457 VAL VAL A . n 
A 1 458 ASP 458 458 458 ASP ASP A . n 
A 1 459 GLU 459 459 459 GLU GLU A . n 
A 1 460 ALA 460 460 460 ALA ALA A . n 
A 1 461 ALA 461 461 461 ALA ALA A . n 
A 1 462 ALA 462 462 462 ALA ALA A . n 
A 1 463 GLU 463 463 463 GLU GLU A . n 
A 1 464 GLY 464 464 464 GLY GLY A . n 
A 1 465 TYR 465 465 465 TYR TYR A . n 
A 1 466 GLY 466 466 466 GLY GLY A . n 
A 1 467 GLU 467 467 467 GLU GLU A . n 
A 1 468 TYR 468 468 468 TYR TYR A . n 
A 1 469 ARG 469 469 469 ARG ARG A . n 
A 1 470 THR 470 470 470 THR THR A . n 
A 1 471 HIS 471 471 471 HIS HIS A . n 
A 1 472 ILE 472 472 472 ILE ILE A . n 
A 1 473 ARG 473 473 473 ARG ARG A . n 
A 1 474 TYR 474 474 474 TYR TYR A . n 
A 1 475 MET 475 475 475 MET MET A . n 
A 1 476 ASP 476 476 476 ASP ASP A . n 
A 1 477 ARG 477 477 477 ARG ARG A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 ALA 479 479 479 ALA ALA A . n 
A 1 480 LYS 480 480 480 LYS LYS A . n 
A 1 481 THR 481 481 481 THR THR A . n 
A 1 482 TYR 482 482 482 TYR TYR A . n 
A 1 483 SER 483 483 483 SER SER A . n 
A 1 484 TRP 484 484 484 TRP TRP A . n 
A 1 485 ASN 485 485 485 ASN ASN A . n 
A 1 486 ASP 486 486 486 ASP ASP A . n 
A 1 487 ASN 487 487 487 ASN ASN A . n 
A 1 488 ALA 488 488 488 ALA ALA A . n 
A 1 489 LEU 489 489 489 LEU LEU A . n 
A 1 490 TRP 490 490 490 TRP TRP A . n 
A 1 491 LYS 491 491 491 LYS LYS A . n 
A 1 492 MET 492 492 492 MET MET A . n 
A 1 493 HIS 493 493 493 HIS HIS A . n 
A 1 494 GLU 494 494 494 GLU GLU A . n 
A 1 495 THR 495 495 495 THR THR A . n 
A 1 496 ILE 496 496 496 ILE ILE A . n 
A 1 497 LYS 497 497 497 LYS LYS A . n 
A 1 498 ASP 498 498 498 ASP ASP A . n 
A 1 499 ALA 499 499 499 ALA ALA A . n 
A 1 500 LEU 500 500 500 LEU LEU A . n 
A 1 501 ASP 501 501 501 ASP ASP A . n 
A 1 502 PRO 502 502 502 PRO PRO A . n 
A 1 503 ASN 503 503 503 ASN ASN A . n 
A 1 504 GLY 504 504 504 GLY GLY A . n 
A 1 505 ILE 505 505 505 ILE ILE A . n 
A 1 506 LEU 506 506 506 LEU LEU A . n 
A 1 507 ALA 507 507 507 ALA ALA A . n 
A 1 508 PRO 508 508 508 PRO PRO A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 LYS 510 510 510 LYS LYS A . n 
A 1 511 SER 511 511 511 SER SER A . n 
A 1 512 GLY 512 512 512 GLY GLY A . n 
A 1 513 ILE 513 513 513 ILE ILE A . n 
A 1 514 TRP 514 514 514 TRP TRP A . n 
A 1 515 GLY 515 515 515 GLY GLY A . n 
A 1 516 LYS 516 516 516 LYS LYS A . n 
A 1 517 ASN 517 517 517 ASN ASN A . n 
A 1 518 ARG 518 518 518 ARG ARG A . n 
A 1 519 ARG 519 519 519 ARG ARG A . n 
A 1 520 LYS 520 520 ?   ?   ?   A . n 
A 1 521 ALA 521 521 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   2   ALA ALA B . n 
B 1 3   ALA 3   3   3   ALA ALA B . n 
B 1 4   PRO 4   4   4   PRO PRO B . n 
B 1 5   LEU 5   5   5   LEU LEU B . n 
B 1 6   PRO 6   6   6   PRO PRO B . n 
B 1 7   GLU 7   7   7   GLU GLU B . n 
B 1 8   GLY 8   8   8   GLY GLY B . n 
B 1 9   VAL 9   9   9   VAL VAL B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  ALA 11  11  11  ALA ALA B . n 
B 1 12  GLU 12  12  12  GLU GLU B . n 
B 1 13  ALA 13  13  13  ALA ALA B . n 
B 1 14  MET 14  14  14  MET MET B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  SER 16  16  16  SER SER B . n 
B 1 17  ALA 17  17  17  ALA ALA B . n 
B 1 18  LEU 18  18  18  LEU LEU B . n 
B 1 19  ASP 19  19  19  ASP ASP B . n 
B 1 20  ARG 20  20  20  ARG ARG B . n 
B 1 21  PHE 21  21  21  PHE PHE B . n 
B 1 22  ALA 22  22  22  ALA ALA B . n 
B 1 23  ARG 23  23  23  ARG ARG B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  VAL 25  25  25  VAL VAL B . n 
B 1 26  GLY 26  26  26  GLY GLY B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  ASP 28  28  28  ASP ASP B . n 
B 1 29  TRP 29  29  29  TRP TRP B . n 
B 1 30  VAL 30  30  30  VAL VAL B . n 
B 1 31  PHE 31  31  31  PHE PHE B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  GLU 33  33  33  GLU GLU B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  LYS 35  35  35  LYS LYS B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  THR 37  37  37  THR THR B . n 
B 1 38  PRO 38  38  38  PRO PRO B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  GLU 40  40  40  GLU GLU B . n 
B 1 41  ASP 41  41  41  ASP ASP B . n 
B 1 42  PRO 42  42  42  PRO PRO B . n 
B 1 43  TYR 43  43  43  TYR TYR B . n 
B 1 44  THR 44  44  44  THR THR B . n 
B 1 45  ILE 45  45  45  ILE ILE B . n 
B 1 46  SER 46  46  46  SER SER B . n 
B 1 47  ASN 47  47  47  ASN ASN B . n 
B 1 48  ASP 48  48  48  ASP ASP B . n 
B 1 49  GLU 49  49  49  GLU GLU B . n 
B 1 50  THR 50  50  50  THR THR B . n 
B 1 51  GLU 51  51  51  GLU GLU B . n 
B 1 52  HIS 52  52  52  HIS HIS B . n 
B 1 53  ARG 53  53  53  ARG ARG B . n 
B 1 54  PRO 54  54  54  PRO PRO B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  ALA 56  56  56  ALA ALA B . n 
B 1 57  ALA 57  57  57  ALA ALA B . n 
B 1 58  VAL 58  58  58  VAL VAL B . n 
B 1 59  ALA 59  59  59  ALA ALA B . n 
B 1 60  PRO 60  60  60  PRO PRO B . n 
B 1 61  ALA 61  61  61  ALA ALA B . n 
B 1 62  SER 62  62  62  SER SER B . n 
B 1 63  THR 63  63  63  THR THR B . n 
B 1 64  GLU 64  64  64  GLU GLU B . n 
B 1 65  GLU 65  65  65  GLU GLU B . n 
B 1 66  VAL 66  66  66  VAL VAL B . n 
B 1 67  GLN 67  67  67  GLN GLN B . n 
B 1 68  GLU 68  68  68  GLU GLU B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  VAL 70  70  70  VAL VAL B . n 
B 1 71  ARG 71  71  71  ARG ARG B . n 
B 1 72  VAL 72  72  72  VAL VAL B . n 
B 1 73  ALA 73  73  73  ALA ALA B . n 
B 1 74  ASN 74  74  74  ASN ASN B . n 
B 1 75  GLU 75  75  75  GLU GLU B . n 
B 1 76  PHE 76  76  76  PHE PHE B . n 
B 1 77  GLY 77  77  77  GLY GLY B . n 
B 1 78  VAL 78  78  78  VAL VAL B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  TRP 81  81  81  TRP TRP B . n 
B 1 82  PRO 82  82  82  PRO PRO B . n 
B 1 83  VAL 83  83  83  VAL VAL B . n 
B 1 84  SER 84  84  84  SER SER B . n 
B 1 85  ARG 85  85  85  ARG ARG B . n 
B 1 86  GLY 86  86  86  GLY GLY B . n 
B 1 87  LYS 87  87  87  LYS LYS B . n 
B 1 88  ASN 88  88  88  ASN ASN B . n 
B 1 89  PHE 89  89  89  PHE PHE B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  TYR 91  91  91  TYR TYR B . n 
B 1 92  GLY 92  92  92  GLY GLY B . n 
B 1 93  GLY 93  93  93  GLY GLY B . n 
B 1 94  ALA 94  94  94  ALA ALA B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  VAL 97  97  97  VAL VAL B . n 
B 1 98  MET 98  98  98  MET MET B . n 
B 1 99  SER 99  99  99  SER SER B . n 
B 1 100 GLY 100 100 100 GLY GLY B . n 
B 1 101 THR 101 101 101 THR THR B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 VAL 103 103 103 VAL VAL B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 MET 106 106 106 MET MET B . n 
B 1 107 ASN 107 107 107 ASN ASN B . n 
B 1 108 ARG 108 108 108 ARG ARG B . n 
B 1 109 MET 109 109 109 MET MET B . n 
B 1 110 ASN 110 110 110 ASN ASN B . n 
B 1 111 ARG 111 111 111 ARG ARG B . n 
B 1 112 ILE 112 112 112 ILE ILE B . n 
B 1 113 LEU 113 113 113 LEU LEU B . n 
B 1 114 GLU 114 114 114 GLU GLU B . n 
B 1 115 VAL 115 115 115 VAL VAL B . n 
B 1 116 ASN 116 116 116 ASN ASN B . n 
B 1 117 GLU 117 117 117 GLU GLU B . n 
B 1 118 GLU 118 118 118 GLU GLU B . n 
B 1 119 PHE 119 119 119 PHE PHE B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 TYR 121 121 121 TYR TYR B . n 
B 1 122 ALA 122 122 122 ALA ALA B . n 
B 1 123 LEU 123 123 123 LEU LEU B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 PRO 126 126 126 PRO PRO B . n 
B 1 127 GLY 127 127 127 GLY GLY B . n 
B 1 128 VAL 128 128 128 VAL VAL B . n 
B 1 129 SER 129 129 129 SER SER B . n 
B 1 130 TYR 130 130 130 TYR TYR B . n 
B 1 131 PHE 131 131 131 PHE PHE B . n 
B 1 132 GLU 132 132 132 GLU GLU B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 TYR 134 134 134 TYR TYR B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 TYR 136 136 136 TYR TYR B . n 
B 1 137 ILE 137 137 137 ILE ILE B . n 
B 1 138 GLN 138 138 138 GLN GLN B . n 
B 1 139 GLU 139 139 139 GLU GLU B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 GLY 141 141 141 GLY GLY B . n 
B 1 142 LEU 142 142 142 LEU LEU B . n 
B 1 143 LYS 143 143 143 LYS LYS B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 TRP 145 145 145 TRP TRP B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 ASP 147 147 147 ASP ASP B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 PRO 149 149 149 PRO PRO B . n 
B 1 150 ASP 150 150 150 ASP ASP B . n 
B 1 151 GLY 151 151 151 GLY GLY B . n 
B 1 152 GLY 152 152 152 GLY GLY B . n 
B 1 153 TRP 153 153 153 TRP TRP B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 SER 155 155 155 SER SER B . n 
B 1 156 VAL 156 156 156 VAL VAL B . n 
B 1 157 VAL 157 157 157 VAL VAL B . n 
B 1 158 GLY 158 158 158 GLY GLY B . n 
B 1 159 ASN 159 159 159 ASN ASN B . n 
B 1 160 ALA 160 160 160 ALA ALA B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 ASP 162 162 162 ASP ASP B . n 
B 1 163 HIS 163 163 163 HIS HIS B . n 
B 1 164 GLY 164 164 164 GLY GLY B . n 
B 1 165 ILE 165 165 165 ILE ILE B . n 
B 1 166 GLY 166 166 166 GLY GLY B . n 
B 1 167 TYR 167 167 167 TYR TYR B . n 
B 1 168 THR 168 168 168 THR THR B . n 
B 1 169 PRO 169 169 169 PRO PRO B . n 
B 1 170 TYR 170 170 170 TYR TYR B . n 
B 1 171 GLY 171 171 171 GLY GLY B . n 
B 1 172 ASP 172 172 172 ASP ASP B . n 
B 1 173 HIS 173 173 173 HIS HIS B . n 
B 1 174 PHE 174 174 174 PHE PHE B . n 
B 1 175 ALA 175 175 175 ALA ALA B . n 
B 1 176 MET 176 176 176 MET MET B . n 
B 1 177 GLN 177 177 177 GLN GLN B . n 
B 1 178 CYS 178 178 178 CYS CYS B . n 
B 1 179 GLY 179 179 179 GLY GLY B . n 
B 1 180 MET 180 180 180 MET MET B . n 
B 1 181 GLU 181 181 181 GLU GLU B . n 
B 1 182 VAL 182 182 182 VAL VAL B . n 
B 1 183 VAL 183 183 183 VAL VAL B . n 
B 1 184 LEU 184 184 184 LEU LEU B . n 
B 1 185 PRO 185 185 185 PRO PRO B . n 
B 1 186 ASN 186 186 186 ASN ASN B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 GLU 188 188 188 GLU GLU B . n 
B 1 189 VAL 189 189 189 VAL VAL B . n 
B 1 190 VAL 190 190 190 VAL VAL B . n 
B 1 191 ARG 191 191 191 ARG ARG B . n 
B 1 192 THR 192 192 192 THR THR B . n 
B 1 193 GLY 193 193 193 GLY GLY B . n 
B 1 194 MET 194 194 194 MET MET B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 ALA 196 196 196 ALA ALA B . n 
B 1 197 MET 197 197 197 MET MET B . n 
B 1 198 PRO 198 198 198 PRO PRO B . n 
B 1 199 GLY 199 199 199 GLY GLY B . n 
B 1 200 ASN 200 200 200 ASN ASN B . n 
B 1 201 ASN 201 201 201 ASN ASN B . n 
B 1 202 THR 202 202 202 THR THR B . n 
B 1 203 TRP 203 203 203 TRP TRP B . n 
B 1 204 GLN 204 204 204 GLN GLN B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 PHE 206 206 206 PHE PHE B . n 
B 1 207 LYS 207 207 207 LYS LYS B . n 
B 1 208 TYR 208 208 208 TYR TYR B . n 
B 1 209 GLY 209 209 209 GLY GLY B . n 
B 1 210 TYR 210 210 210 TYR TYR B . n 
B 1 211 GLY 211 211 211 GLY GLY B . n 
B 1 212 PRO 212 212 212 PRO PRO B . n 
B 1 213 TYR 213 213 213 TYR TYR B . n 
B 1 214 VAL 214 214 214 VAL VAL B . n 
B 1 215 ASP 215 215 215 ASP ASP B . n 
B 1 216 GLY 216 216 216 GLY GLY B . n 
B 1 217 ILE 217 217 217 ILE ILE B . n 
B 1 218 PHE 218 218 218 PHE PHE B . n 
B 1 219 SER 219 219 219 SER SER B . n 
B 1 220 GLN 220 220 220 GLN GLN B . n 
B 1 221 SER 221 221 221 SER SER B . n 
B 1 222 ASN 222 222 222 ASN ASN B . n 
B 1 223 PHE 223 223 223 PHE PHE B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 VAL 226 226 226 VAL VAL B . n 
B 1 227 THR 227 227 227 THR THR B . n 
B 1 228 LYS 228 228 228 LYS LYS B . n 
B 1 229 MET 229 229 229 MET MET B . n 
B 1 230 GLY 230 230 230 GLY GLY B . n 
B 1 231 ILE 231 231 231 ILE ILE B . n 
B 1 232 TRP 232 232 232 TRP TRP B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 MET 234 234 234 MET MET B . n 
B 1 235 PRO 235 235 235 PRO PRO B . n 
B 1 236 GLU 236 236 236 GLU GLU B . n 
B 1 237 PRO 237 237 237 PRO PRO B . n 
B 1 238 ALA 238 238 238 ALA ALA B . n 
B 1 239 GLY 239 239 239 GLY GLY B . n 
B 1 240 TYR 240 240 240 TYR TYR B . n 
B 1 241 ARG 241 241 241 ARG ARG B . n 
B 1 242 PRO 242 242 242 PRO PRO B . n 
B 1 243 TYR 243 243 243 TYR TYR B . n 
B 1 244 LEU 244 244 244 LEU LEU B . n 
B 1 245 ILE 245 245 245 ILE ILE B . n 
B 1 246 THR 246 246 246 THR THR B . n 
B 1 247 PHE 247 247 247 PHE PHE B . n 
B 1 248 GLU 248 248 248 GLU GLU B . n 
B 1 249 ASN 249 249 249 ASN ASN B . n 
B 1 250 GLU 250 250 250 GLU GLU B . n 
B 1 251 ASP 251 251 251 ASP ASP B . n 
B 1 252 ASP 252 252 252 ASP ASP B . n 
B 1 253 ILE 253 253 253 ILE ILE B . n 
B 1 254 GLU 254 254 254 GLU GLU B . n 
B 1 255 THR 255 255 255 THR THR B . n 
B 1 256 VAL 256 256 256 VAL VAL B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLU 258 258 258 GLU GLU B . n 
B 1 259 ARG 259 259 259 ARG ARG B . n 
B 1 260 LEU 260 260 260 LEU LEU B . n 
B 1 261 ARG 261 261 261 ARG ARG B . n 
B 1 262 PRO 262 262 262 PRO PRO B . n 
B 1 263 LEU 263 263 263 LEU LEU B . n 
B 1 264 LYS 264 264 264 LYS LYS B . n 
B 1 265 VAL 265 265 265 VAL VAL B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 GLY 267 267 267 GLY GLY B . n 
B 1 268 VAL 268 268 268 VAL VAL B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 GLN 270 270 270 GLN GLN B . n 
B 1 271 ASN 271 271 271 ASN ASN B . n 
B 1 272 GLY 272 272 272 GLY GLY B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 THR 274 274 274 THR THR B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 SER 277 277 277 SER SER B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 VAL 279 279 279 VAL VAL B . n 
B 1 280 LEU 280 280 280 LEU LEU B . n 
B 1 281 ASP 281 281 281 ASP ASP B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 ALA 283 283 283 ALA ALA B . n 
B 1 284 ILE 284 284 284 ILE ILE B . n 
B 1 285 THR 285 285 285 THR THR B . n 
B 1 286 ARG 286 286 286 ARG ARG B . n 
B 1 287 THR 287 287 287 THR THR B . n 
B 1 288 LYS 288 288 288 LYS LYS B . n 
B 1 289 SER 289 289 289 SER SER B . n 
B 1 290 GLN 290 290 290 GLN GLN B . n 
B 1 291 TYR 291 291 291 TYR TYR B . n 
B 1 292 TYR 292 292 292 TYR TYR B . n 
B 1 293 ASP 293 293 293 ASP ASP B . n 
B 1 294 GLY 294 294 294 GLY GLY B . n 
B 1 295 ASP 295 295 295 ASP ASP B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 PRO 297 297 297 PRO PRO B . n 
B 1 298 ILE 298 298 298 ILE ILE B . n 
B 1 299 PRO 299 299 299 PRO PRO B . n 
B 1 300 PRO 300 300 300 PRO PRO B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 VAL 302 302 302 VAL VAL B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 LYS 304 304 304 LYS LYS B . n 
B 1 305 THR 305 305 305 THR THR B . n 
B 1 306 MET 306 306 306 MET MET B . n 
B 1 307 MET 307 307 307 MET MET B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 ASP 309 309 309 ASP ASP B . n 
B 1 310 LEU 310 310 310 LEU LEU B . n 
B 1 311 ASP 311 311 311 ASP ASP B . n 
B 1 312 LEU 312 312 312 LEU LEU B . n 
B 1 313 GLY 313 313 313 GLY GLY B . n 
B 1 314 MET 314 314 314 MET MET B . n 
B 1 315 TRP 315 315 315 TRP TRP B . n 
B 1 316 ASN 316 316 316 ASN ASN B . n 
B 1 317 PHE 317 317 317 PHE PHE B . n 
B 1 318 CYS 318 318 318 CYS CYS B . n 
B 1 319 GLY 319 319 319 GLY GLY B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 LEU 321 321 321 LEU LEU B . n 
B 1 322 TYR 322 322 322 TYR TYR B . n 
B 1 323 GLY 323 323 323 GLY GLY B . n 
B 1 324 PRO 324 324 324 PRO PRO B . n 
B 1 325 PRO 325 325 325 PRO PRO B . n 
B 1 326 PRO 326 326 326 PRO PRO B . n 
B 1 327 VAL 327 327 327 VAL VAL B . n 
B 1 328 MET 328 328 328 MET MET B . n 
B 1 329 ASP 329 329 329 ASP ASP B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 LEU 331 331 331 LEU LEU B . n 
B 1 332 TRP 332 332 332 TRP TRP B . n 
B 1 333 THR 333 333 333 THR THR B . n 
B 1 334 ALA 334 334 334 ALA ALA B . n 
B 1 335 ILE 335 335 335 ILE ILE B . n 
B 1 336 ARG 336 336 336 ARG ARG B . n 
B 1 337 ASP 337 337 337 ASP ASP B . n 
B 1 338 SER 338 338 338 SER SER B . n 
B 1 339 PHE 339 339 339 PHE PHE B . n 
B 1 340 ALA 340 340 340 ALA ALA B . n 
B 1 341 ASP 341 341 341 ASP ASP B . n 
B 1 342 ILE 342 342 342 ILE ILE B . n 
B 1 343 PRO 343 343 343 PRO PRO B . n 
B 1 344 GLY 344 344 344 GLY GLY B . n 
B 1 345 VAL 345 345 345 VAL VAL B . n 
B 1 346 LYS 346 346 346 LYS LYS B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 TYR 348 348 348 TYR TYR B . n 
B 1 349 PHE 349 349 349 PHE PHE B . n 
B 1 350 PRO 350 350 350 PRO PRO B . n 
B 1 351 GLU 351 351 351 GLU GLU B . n 
B 1 352 ASP 352 352 352 ASP ASP B . n 
B 1 353 ARG 353 353 353 ARG ARG B . n 
B 1 354 ARG 354 354 354 ARG ARG B . n 
B 1 355 HIS 355 355 355 HIS HIS B . n 
B 1 356 LYS 356 356 356 LYS LYS B . n 
B 1 357 VAL 357 357 357 VAL VAL B . n 
B 1 358 ASP 358 358 358 ASP ASP B . n 
B 1 359 LEU 359 359 359 LEU LEU B . n 
B 1 360 LEU 360 360 360 LEU LEU B . n 
B 1 361 LEU 361 361 361 LEU LEU B . n 
B 1 362 HIS 362 362 362 HIS HIS B . n 
B 1 363 ARG 363 363 363 ARG ARG B . n 
B 1 364 ALA 364 364 364 ALA ALA B . n 
B 1 365 GLU 365 365 365 GLU GLU B . n 
B 1 366 THR 366 366 366 THR THR B . n 
B 1 367 MET 367 367 367 MET MET B . n 
B 1 368 LYS 368 368 368 LYS LYS B . n 
B 1 369 GLY 369 369 369 GLY GLY B . n 
B 1 370 VAL 370 370 370 VAL VAL B . n 
B 1 371 PRO 371 371 371 PRO PRO B . n 
B 1 372 LYS 372 372 372 LYS LYS B . n 
B 1 373 LEU 373 373 373 LEU LEU B . n 
B 1 374 THR 374 374 374 THR THR B . n 
B 1 375 GLU 375 375 375 GLU GLU B . n 
B 1 376 PHE 376 376 376 PHE PHE B . n 
B 1 377 ASN 377 377 377 ASN ASN B . n 
B 1 378 PHE 378 378 378 PHE PHE B . n 
B 1 379 LEU 379 379 379 LEU LEU B . n 
B 1 380 ASN 380 380 380 ASN ASN B . n 
B 1 381 TRP 381 381 381 TRP TRP B . n 
B 1 382 ASP 382 382 382 ASP ASP B . n 
B 1 383 GLY 383 383 383 GLY GLY B . n 
B 1 384 GLY 384 384 384 GLY GLY B . n 
B 1 385 GLY 385 385 385 GLY GLY B . n 
B 1 386 GLY 386 386 386 GLY GLY B . n 
B 1 387 HIS 387 387 387 HIS HIS B . n 
B 1 388 VAL 388 388 388 VAL VAL B . n 
B 1 389 GLY 389 389 389 GLY GLY B . n 
B 1 390 PHE 390 390 390 PHE PHE B . n 
B 1 391 SER 391 391 391 SER SER B . n 
B 1 392 PRO 392 392 392 PRO PRO B . n 
B 1 393 VAL 393 393 393 VAL VAL B . n 
B 1 394 SER 394 394 394 SER SER B . n 
B 1 395 PRO 395 395 395 PRO PRO B . n 
B 1 396 ILE 396 396 396 ILE ILE B . n 
B 1 397 THR 397 397 397 THR THR B . n 
B 1 398 GLY 398 398 398 GLY GLY B . n 
B 1 399 LYS 399 399 399 LYS LYS B . n 
B 1 400 ASP 400 400 400 ASP ASP B . n 
B 1 401 ALA 401 401 401 ALA ALA B . n 
B 1 402 ILE 402 402 402 ILE ILE B . n 
B 1 403 LYS 403 403 403 LYS LYS B . n 
B 1 404 GLN 404 404 404 GLN GLN B . n 
B 1 405 TYR 405 405 405 TYR TYR B . n 
B 1 406 ASN 406 406 406 ASN ASN B . n 
B 1 407 MET 407 407 407 MET MET B . n 
B 1 408 VAL 408 408 408 VAL VAL B . n 
B 1 409 SER 409 409 409 SER SER B . n 
B 1 410 SER 410 410 410 SER SER B . n 
B 1 411 ARG 411 411 411 ARG ARG B . n 
B 1 412 VAL 412 412 412 VAL VAL B . n 
B 1 413 ARG 413 413 413 ARG ARG B . n 
B 1 414 GLU 414 414 414 GLU GLU B . n 
B 1 415 TYR 415 415 415 TYR TYR B . n 
B 1 416 GLY 416 416 416 GLY GLY B . n 
B 1 417 PHE 417 417 417 PHE PHE B . n 
B 1 418 ASP 418 418 418 ASP ASP B . n 
B 1 419 TYR 419 419 419 TYR TYR B . n 
B 1 420 MET 420 420 420 MET MET B . n 
B 1 421 GLY 421 421 421 GLY GLY B . n 
B 1 422 LEU 422 422 422 LEU LEU B . n 
B 1 423 LEU 423 423 423 LEU LEU B . n 
B 1 424 ALA 424 424 424 ALA ALA B . n 
B 1 425 ILE 425 425 425 ILE ILE B . n 
B 1 426 GLY 426 426 426 GLY GLY B . n 
B 1 427 TRP 427 427 427 TRP TRP B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 ASP 429 429 429 ASP ASP B . n 
B 1 430 LEU 430 430 430 LEU LEU B . n 
B 1 431 HIS 431 431 431 HIS HIS B . n 
B 1 432 HIS 432 432 432 HIS HIS B . n 
B 1 433 VAL 433 433 433 VAL VAL B . n 
B 1 434 THR 434 434 434 THR THR B . n 
B 1 435 VAL 435 435 435 VAL VAL B . n 
B 1 436 ILE 436 436 436 ILE ILE B . n 
B 1 437 VAL 437 437 437 VAL VAL B . n 
B 1 438 TYR 438 438 438 TYR TYR B . n 
B 1 439 ASP 439 439 439 ASP ASP B . n 
B 1 440 LYS 440 440 440 LYS LYS B . n 
B 1 441 THR 441 441 441 THR THR B . n 
B 1 442 ASP 442 442 442 ASP ASP B . n 
B 1 443 PRO 443 443 443 PRO PRO B . n 
B 1 444 ASP 444 444 444 ASP ASP B . n 
B 1 445 GLU 445 445 445 GLU GLU B . n 
B 1 446 ARG 446 446 446 ARG ARG B . n 
B 1 447 LYS 447 447 447 LYS LYS B . n 
B 1 448 LYS 448 448 448 LYS LYS B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 ASP 450 450 450 ASP ASP B . n 
B 1 451 GLU 451 451 451 GLU GLU B . n 
B 1 452 LEU 452 452 452 LEU LEU B . n 
B 1 453 PHE 453 453 453 PHE PHE B . n 
B 1 454 ASN 454 454 454 ASN ASN B . n 
B 1 455 ILE 455 455 455 ILE ILE B . n 
B 1 456 LEU 456 456 456 LEU LEU B . n 
B 1 457 VAL 457 457 457 VAL VAL B . n 
B 1 458 ASP 458 458 458 ASP ASP B . n 
B 1 459 GLU 459 459 459 GLU GLU B . n 
B 1 460 ALA 460 460 460 ALA ALA B . n 
B 1 461 ALA 461 461 461 ALA ALA B . n 
B 1 462 ALA 462 462 462 ALA ALA B . n 
B 1 463 GLU 463 463 463 GLU GLU B . n 
B 1 464 GLY 464 464 464 GLY GLY B . n 
B 1 465 TYR 465 465 465 TYR TYR B . n 
B 1 466 GLY 466 466 466 GLY GLY B . n 
B 1 467 GLU 467 467 467 GLU GLU B . n 
B 1 468 TYR 468 468 468 TYR TYR B . n 
B 1 469 ARG 469 469 469 ARG ARG B . n 
B 1 470 THR 470 470 470 THR THR B . n 
B 1 471 HIS 471 471 471 HIS HIS B . n 
B 1 472 ILE 472 472 472 ILE ILE B . n 
B 1 473 ARG 473 473 473 ARG ARG B . n 
B 1 474 TYR 474 474 474 TYR TYR B . n 
B 1 475 MET 475 475 475 MET MET B . n 
B 1 476 ASP 476 476 476 ASP ASP B . n 
B 1 477 ARG 477 477 477 ARG ARG B . n 
B 1 478 ILE 478 478 478 ILE ILE B . n 
B 1 479 ALA 479 479 479 ALA ALA B . n 
B 1 480 LYS 480 480 480 LYS LYS B . n 
B 1 481 THR 481 481 481 THR THR B . n 
B 1 482 TYR 482 482 482 TYR TYR B . n 
B 1 483 SER 483 483 483 SER SER B . n 
B 1 484 TRP 484 484 484 TRP TRP B . n 
B 1 485 ASN 485 485 485 ASN ASN B . n 
B 1 486 ASP 486 486 486 ASP ASP B . n 
B 1 487 ASN 487 487 487 ASN ASN B . n 
B 1 488 ALA 488 488 488 ALA ALA B . n 
B 1 489 LEU 489 489 489 LEU LEU B . n 
B 1 490 TRP 490 490 490 TRP TRP B . n 
B 1 491 LYS 491 491 491 LYS LYS B . n 
B 1 492 MET 492 492 492 MET MET B . n 
B 1 493 HIS 493 493 493 HIS HIS B . n 
B 1 494 GLU 494 494 494 GLU GLU B . n 
B 1 495 THR 495 495 495 THR THR B . n 
B 1 496 ILE 496 496 496 ILE ILE B . n 
B 1 497 LYS 497 497 497 LYS LYS B . n 
B 1 498 ASP 498 498 498 ASP ASP B . n 
B 1 499 ALA 499 499 499 ALA ALA B . n 
B 1 500 LEU 500 500 500 LEU LEU B . n 
B 1 501 ASP 501 501 501 ASP ASP B . n 
B 1 502 PRO 502 502 502 PRO PRO B . n 
B 1 503 ASN 503 503 503 ASN ASN B . n 
B 1 504 GLY 504 504 504 GLY GLY B . n 
B 1 505 ILE 505 505 505 ILE ILE B . n 
B 1 506 LEU 506 506 506 LEU LEU B . n 
B 1 507 ALA 507 507 507 ALA ALA B . n 
B 1 508 PRO 508 508 508 PRO PRO B . n 
B 1 509 GLY 509 509 509 GLY GLY B . n 
B 1 510 LYS 510 510 510 LYS LYS B . n 
B 1 511 SER 511 511 511 SER SER B . n 
B 1 512 GLY 512 512 512 GLY GLY B . n 
B 1 513 ILE 513 513 513 ILE ILE B . n 
B 1 514 TRP 514 514 514 TRP TRP B . n 
B 1 515 GLY 515 515 515 GLY GLY B . n 
B 1 516 LYS 516 516 516 LYS LYS B . n 
B 1 517 ASN 517 517 517 ASN ASN B . n 
B 1 518 ARG 518 518 518 ARG ARG B . n 
B 1 519 ARG 519 519 519 ARG ARG B . n 
B 1 520 LYS 520 520 ?   ?   ?   B . n 
B 1 521 ALA 521 521 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   ALA 2   2   2   ALA ALA C . n 
C 1 3   ALA 3   3   3   ALA ALA C . n 
C 1 4   PRO 4   4   4   PRO PRO C . n 
C 1 5   LEU 5   5   5   LEU LEU C . n 
C 1 6   PRO 6   6   6   PRO PRO C . n 
C 1 7   GLU 7   7   7   GLU GLU C . n 
C 1 8   GLY 8   8   8   GLY GLY C . n 
C 1 9   VAL 9   9   9   VAL VAL C . n 
C 1 10  SER 10  10  10  SER SER C . n 
C 1 11  ALA 11  11  11  ALA ALA C . n 
C 1 12  GLU 12  12  12  GLU GLU C . n 
C 1 13  ALA 13  13  13  ALA ALA C . n 
C 1 14  MET 14  14  14  MET MET C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  SER 16  16  16  SER SER C . n 
C 1 17  ALA 17  17  17  ALA ALA C . n 
C 1 18  LEU 18  18  18  LEU LEU C . n 
C 1 19  ASP 19  19  19  ASP ASP C . n 
C 1 20  ARG 20  20  20  ARG ARG C . n 
C 1 21  PHE 21  21  21  PHE PHE C . n 
C 1 22  ALA 22  22  22  ALA ALA C . n 
C 1 23  ARG 23  23  23  ARG ARG C . n 
C 1 24  ILE 24  24  24  ILE ILE C . n 
C 1 25  VAL 25  25  25  VAL VAL C . n 
C 1 26  GLY 26  26  26  GLY GLY C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  ASP 28  28  28  ASP ASP C . n 
C 1 29  TRP 29  29  29  TRP TRP C . n 
C 1 30  VAL 30  30  30  VAL VAL C . n 
C 1 31  PHE 31  31  31  PHE PHE C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  GLU 33  33  33  GLU GLU C . n 
C 1 34  ASP 34  34  34  ASP ASP C . n 
C 1 35  LYS 35  35  35  LYS LYS C . n 
C 1 36  ILE 36  36  36  ILE ILE C . n 
C 1 37  THR 37  37  37  THR THR C . n 
C 1 38  PRO 38  38  38  PRO PRO C . n 
C 1 39  TYR 39  39  39  TYR TYR C . n 
C 1 40  GLU 40  40  40  GLU GLU C . n 
C 1 41  ASP 41  41  41  ASP ASP C . n 
C 1 42  PRO 42  42  42  PRO PRO C . n 
C 1 43  TYR 43  43  43  TYR TYR C . n 
C 1 44  THR 44  44  44  THR THR C . n 
C 1 45  ILE 45  45  45  ILE ILE C . n 
C 1 46  SER 46  46  46  SER SER C . n 
C 1 47  ASN 47  47  47  ASN ASN C . n 
C 1 48  ASP 48  48  48  ASP ASP C . n 
C 1 49  GLU 49  49  49  GLU GLU C . n 
C 1 50  THR 50  50  50  THR THR C . n 
C 1 51  GLU 51  51  51  GLU GLU C . n 
C 1 52  HIS 52  52  52  HIS HIS C . n 
C 1 53  ARG 53  53  53  ARG ARG C . n 
C 1 54  PRO 54  54  54  PRO PRO C . n 
C 1 55  TYR 55  55  55  TYR TYR C . n 
C 1 56  ALA 56  56  56  ALA ALA C . n 
C 1 57  ALA 57  57  57  ALA ALA C . n 
C 1 58  VAL 58  58  58  VAL VAL C . n 
C 1 59  ALA 59  59  59  ALA ALA C . n 
C 1 60  PRO 60  60  60  PRO PRO C . n 
C 1 61  ALA 61  61  61  ALA ALA C . n 
C 1 62  SER 62  62  62  SER SER C . n 
C 1 63  THR 63  63  63  THR THR C . n 
C 1 64  GLU 64  64  64  GLU GLU C . n 
C 1 65  GLU 65  65  65  GLU GLU C . n 
C 1 66  VAL 66  66  66  VAL VAL C . n 
C 1 67  GLN 67  67  67  GLN GLN C . n 
C 1 68  GLU 68  68  68  GLU GLU C . n 
C 1 69  ILE 69  69  69  ILE ILE C . n 
C 1 70  VAL 70  70  70  VAL VAL C . n 
C 1 71  ARG 71  71  71  ARG ARG C . n 
C 1 72  VAL 72  72  72  VAL VAL C . n 
C 1 73  ALA 73  73  73  ALA ALA C . n 
C 1 74  ASN 74  74  74  ASN ASN C . n 
C 1 75  GLU 75  75  75  GLU GLU C . n 
C 1 76  PHE 76  76  76  PHE PHE C . n 
C 1 77  GLY 77  77  77  GLY GLY C . n 
C 1 78  VAL 78  78  78  VAL VAL C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  LEU 80  80  80  LEU LEU C . n 
C 1 81  TRP 81  81  81  TRP TRP C . n 
C 1 82  PRO 82  82  82  PRO PRO C . n 
C 1 83  VAL 83  83  83  VAL VAL C . n 
C 1 84  SER 84  84  84  SER SER C . n 
C 1 85  ARG 85  85  85  ARG ARG C . n 
C 1 86  GLY 86  86  86  GLY GLY C . n 
C 1 87  LYS 87  87  87  LYS LYS C . n 
C 1 88  ASN 88  88  88  ASN ASN C . n 
C 1 89  PHE 89  89  89  PHE PHE C . n 
C 1 90  ALA 90  90  90  ALA ALA C . n 
C 1 91  TYR 91  91  91  TYR TYR C . n 
C 1 92  GLY 92  92  92  GLY GLY C . n 
C 1 93  GLY 93  93  93  GLY GLY C . n 
C 1 94  ALA 94  94  94  ALA ALA C . n 
C 1 95  ALA 95  95  95  ALA ALA C . n 
C 1 96  PRO 96  96  96  PRO PRO C . n 
C 1 97  VAL 97  97  97  VAL VAL C . n 
C 1 98  MET 98  98  98  MET MET C . n 
C 1 99  SER 99  99  99  SER SER C . n 
C 1 100 GLY 100 100 100 GLY GLY C . n 
C 1 101 THR 101 101 101 THR THR C . n 
C 1 102 VAL 102 102 102 VAL VAL C . n 
C 1 103 VAL 103 103 103 VAL VAL C . n 
C 1 104 LEU 104 104 104 LEU LEU C . n 
C 1 105 ASP 105 105 105 ASP ASP C . n 
C 1 106 MET 106 106 106 MET MET C . n 
C 1 107 ASN 107 107 107 ASN ASN C . n 
C 1 108 ARG 108 108 108 ARG ARG C . n 
C 1 109 MET 109 109 109 MET MET C . n 
C 1 110 ASN 110 110 110 ASN ASN C . n 
C 1 111 ARG 111 111 111 ARG ARG C . n 
C 1 112 ILE 112 112 112 ILE ILE C . n 
C 1 113 LEU 113 113 113 LEU LEU C . n 
C 1 114 GLU 114 114 114 GLU GLU C . n 
C 1 115 VAL 115 115 115 VAL VAL C . n 
C 1 116 ASN 116 116 116 ASN ASN C . n 
C 1 117 GLU 117 117 117 GLU GLU C . n 
C 1 118 GLU 118 118 118 GLU GLU C . n 
C 1 119 PHE 119 119 119 PHE PHE C . n 
C 1 120 GLY 120 120 120 GLY GLY C . n 
C 1 121 TYR 121 121 121 TYR TYR C . n 
C 1 122 ALA 122 122 122 ALA ALA C . n 
C 1 123 LEU 123 123 123 LEU LEU C . n 
C 1 124 VAL 124 124 124 VAL VAL C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 PRO 126 126 126 PRO PRO C . n 
C 1 127 GLY 127 127 127 GLY GLY C . n 
C 1 128 VAL 128 128 128 VAL VAL C . n 
C 1 129 SER 129 129 129 SER SER C . n 
C 1 130 TYR 130 130 130 TYR TYR C . n 
C 1 131 PHE 131 131 131 PHE PHE C . n 
C 1 132 GLU 132 132 132 GLU GLU C . n 
C 1 133 LEU 133 133 133 LEU LEU C . n 
C 1 134 TYR 134 134 134 TYR TYR C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 TYR 136 136 136 TYR TYR C . n 
C 1 137 ILE 137 137 137 ILE ILE C . n 
C 1 138 GLN 138 138 138 GLN GLN C . n 
C 1 139 GLU 139 139 139 GLU GLU C . n 
C 1 140 LYS 140 140 140 LYS LYS C . n 
C 1 141 GLY 141 141 141 GLY GLY C . n 
C 1 142 LEU 142 142 142 LEU LEU C . n 
C 1 143 LYS 143 143 143 LYS LYS C . n 
C 1 144 LEU 144 144 144 LEU LEU C . n 
C 1 145 TRP 145 145 145 TRP TRP C . n 
C 1 146 ILE 146 146 146 ILE ILE C . n 
C 1 147 ASP 147 147 147 ASP ASP C . n 
C 1 148 VAL 148 148 148 VAL VAL C . n 
C 1 149 PRO 149 149 149 PRO PRO C . n 
C 1 150 ASP 150 150 150 ASP ASP C . n 
C 1 151 GLY 151 151 151 GLY GLY C . n 
C 1 152 GLY 152 152 152 GLY GLY C . n 
C 1 153 TRP 153 153 153 TRP TRP C . n 
C 1 154 GLY 154 154 154 GLY GLY C . n 
C 1 155 SER 155 155 155 SER SER C . n 
C 1 156 VAL 156 156 156 VAL VAL C . n 
C 1 157 VAL 157 157 157 VAL VAL C . n 
C 1 158 GLY 158 158 158 GLY GLY C . n 
C 1 159 ASN 159 159 159 ASN ASN C . n 
C 1 160 ALA 160 160 160 ALA ALA C . n 
C 1 161 LEU 161 161 161 LEU LEU C . n 
C 1 162 ASP 162 162 162 ASP ASP C . n 
C 1 163 HIS 163 163 163 HIS HIS C . n 
C 1 164 GLY 164 164 164 GLY GLY C . n 
C 1 165 ILE 165 165 165 ILE ILE C . n 
C 1 166 GLY 166 166 166 GLY GLY C . n 
C 1 167 TYR 167 167 167 TYR TYR C . n 
C 1 168 THR 168 168 168 THR THR C . n 
C 1 169 PRO 169 169 169 PRO PRO C . n 
C 1 170 TYR 170 170 170 TYR TYR C . n 
C 1 171 GLY 171 171 171 GLY GLY C . n 
C 1 172 ASP 172 172 172 ASP ASP C . n 
C 1 173 HIS 173 173 173 HIS HIS C . n 
C 1 174 PHE 174 174 174 PHE PHE C . n 
C 1 175 ALA 175 175 175 ALA ALA C . n 
C 1 176 MET 176 176 176 MET MET C . n 
C 1 177 GLN 177 177 177 GLN GLN C . n 
C 1 178 CYS 178 178 178 CYS CYS C . n 
C 1 179 GLY 179 179 179 GLY GLY C . n 
C 1 180 MET 180 180 180 MET MET C . n 
C 1 181 GLU 181 181 181 GLU GLU C . n 
C 1 182 VAL 182 182 182 VAL VAL C . n 
C 1 183 VAL 183 183 183 VAL VAL C . n 
C 1 184 LEU 184 184 184 LEU LEU C . n 
C 1 185 PRO 185 185 185 PRO PRO C . n 
C 1 186 ASN 186 186 186 ASN ASN C . n 
C 1 187 GLY 187 187 187 GLY GLY C . n 
C 1 188 GLU 188 188 188 GLU GLU C . n 
C 1 189 VAL 189 189 189 VAL VAL C . n 
C 1 190 VAL 190 190 190 VAL VAL C . n 
C 1 191 ARG 191 191 191 ARG ARG C . n 
C 1 192 THR 192 192 192 THR THR C . n 
C 1 193 GLY 193 193 193 GLY GLY C . n 
C 1 194 MET 194 194 194 MET MET C . n 
C 1 195 GLY 195 195 195 GLY GLY C . n 
C 1 196 ALA 196 196 196 ALA ALA C . n 
C 1 197 MET 197 197 197 MET MET C . n 
C 1 198 PRO 198 198 198 PRO PRO C . n 
C 1 199 GLY 199 199 199 GLY GLY C . n 
C 1 200 ASN 200 200 200 ASN ASN C . n 
C 1 201 ASN 201 201 201 ASN ASN C . n 
C 1 202 THR 202 202 202 THR THR C . n 
C 1 203 TRP 203 203 203 TRP TRP C . n 
C 1 204 GLN 204 204 204 GLN GLN C . n 
C 1 205 LEU 205 205 205 LEU LEU C . n 
C 1 206 PHE 206 206 206 PHE PHE C . n 
C 1 207 LYS 207 207 207 LYS LYS C . n 
C 1 208 TYR 208 208 208 TYR TYR C . n 
C 1 209 GLY 209 209 209 GLY GLY C . n 
C 1 210 TYR 210 210 210 TYR TYR C . n 
C 1 211 GLY 211 211 211 GLY GLY C . n 
C 1 212 PRO 212 212 212 PRO PRO C . n 
C 1 213 TYR 213 213 213 TYR TYR C . n 
C 1 214 VAL 214 214 214 VAL VAL C . n 
C 1 215 ASP 215 215 215 ASP ASP C . n 
C 1 216 GLY 216 216 216 GLY GLY C . n 
C 1 217 ILE 217 217 217 ILE ILE C . n 
C 1 218 PHE 218 218 218 PHE PHE C . n 
C 1 219 SER 219 219 219 SER SER C . n 
C 1 220 GLN 220 220 220 GLN GLN C . n 
C 1 221 SER 221 221 221 SER SER C . n 
C 1 222 ASN 222 222 222 ASN ASN C . n 
C 1 223 PHE 223 223 223 PHE PHE C . n 
C 1 224 GLY 224 224 224 GLY GLY C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 VAL 226 226 226 VAL VAL C . n 
C 1 227 THR 227 227 227 THR THR C . n 
C 1 228 LYS 228 228 228 LYS LYS C . n 
C 1 229 MET 229 229 229 MET MET C . n 
C 1 230 GLY 230 230 230 GLY GLY C . n 
C 1 231 ILE 231 231 231 ILE ILE C . n 
C 1 232 TRP 232 232 232 TRP TRP C . n 
C 1 233 LEU 233 233 233 LEU LEU C . n 
C 1 234 MET 234 234 234 MET MET C . n 
C 1 235 PRO 235 235 235 PRO PRO C . n 
C 1 236 GLU 236 236 236 GLU GLU C . n 
C 1 237 PRO 237 237 237 PRO PRO C . n 
C 1 238 ALA 238 238 238 ALA ALA C . n 
C 1 239 GLY 239 239 239 GLY GLY C . n 
C 1 240 TYR 240 240 240 TYR TYR C . n 
C 1 241 ARG 241 241 241 ARG ARG C . n 
C 1 242 PRO 242 242 242 PRO PRO C . n 
C 1 243 TYR 243 243 243 TYR TYR C . n 
C 1 244 LEU 244 244 244 LEU LEU C . n 
C 1 245 ILE 245 245 245 ILE ILE C . n 
C 1 246 THR 246 246 246 THR THR C . n 
C 1 247 PHE 247 247 247 PHE PHE C . n 
C 1 248 GLU 248 248 248 GLU GLU C . n 
C 1 249 ASN 249 249 249 ASN ASN C . n 
C 1 250 GLU 250 250 250 GLU GLU C . n 
C 1 251 ASP 251 251 251 ASP ASP C . n 
C 1 252 ASP 252 252 252 ASP ASP C . n 
C 1 253 ILE 253 253 253 ILE ILE C . n 
C 1 254 GLU 254 254 254 GLU GLU C . n 
C 1 255 THR 255 255 255 THR THR C . n 
C 1 256 VAL 256 256 256 VAL VAL C . n 
C 1 257 THR 257 257 257 THR THR C . n 
C 1 258 GLU 258 258 258 GLU GLU C . n 
C 1 259 ARG 259 259 259 ARG ARG C . n 
C 1 260 LEU 260 260 260 LEU LEU C . n 
C 1 261 ARG 261 261 261 ARG ARG C . n 
C 1 262 PRO 262 262 262 PRO PRO C . n 
C 1 263 LEU 263 263 263 LEU LEU C . n 
C 1 264 LYS 264 264 264 LYS LYS C . n 
C 1 265 VAL 265 265 265 VAL VAL C . n 
C 1 266 ALA 266 266 266 ALA ALA C . n 
C 1 267 GLY 267 267 267 GLY GLY C . n 
C 1 268 VAL 268 268 268 VAL VAL C . n 
C 1 269 ILE 269 269 269 ILE ILE C . n 
C 1 270 GLN 270 270 270 GLN GLN C . n 
C 1 271 ASN 271 271 271 ASN ASN C . n 
C 1 272 GLY 272 272 272 GLY GLY C . n 
C 1 273 ALA 273 273 273 ALA ALA C . n 
C 1 274 THR 274 274 274 THR THR C . n 
C 1 275 VAL 275 275 275 VAL VAL C . n 
C 1 276 ARG 276 276 276 ARG ARG C . n 
C 1 277 SER 277 277 277 SER SER C . n 
C 1 278 LEU 278 278 278 LEU LEU C . n 
C 1 279 VAL 279 279 279 VAL VAL C . n 
C 1 280 LEU 280 280 280 LEU LEU C . n 
C 1 281 ASP 281 281 281 ASP ASP C . n 
C 1 282 ALA 282 282 282 ALA ALA C . n 
C 1 283 ALA 283 283 283 ALA ALA C . n 
C 1 284 ILE 284 284 284 ILE ILE C . n 
C 1 285 THR 285 285 285 THR THR C . n 
C 1 286 ARG 286 286 286 ARG ARG C . n 
C 1 287 THR 287 287 287 THR THR C . n 
C 1 288 LYS 288 288 288 LYS LYS C . n 
C 1 289 SER 289 289 289 SER SER C . n 
C 1 290 GLN 290 290 290 GLN GLN C . n 
C 1 291 TYR 291 291 291 TYR TYR C . n 
C 1 292 TYR 292 292 292 TYR TYR C . n 
C 1 293 ASP 293 293 293 ASP ASP C . n 
C 1 294 GLY 294 294 294 GLY GLY C . n 
C 1 295 ASP 295 295 295 ASP ASP C . n 
C 1 296 GLY 296 296 296 GLY GLY C . n 
C 1 297 PRO 297 297 297 PRO PRO C . n 
C 1 298 ILE 298 298 298 ILE ILE C . n 
C 1 299 PRO 299 299 299 PRO PRO C . n 
C 1 300 PRO 300 300 300 PRO PRO C . n 
C 1 301 SER 301 301 301 SER SER C . n 
C 1 302 VAL 302 302 302 VAL VAL C . n 
C 1 303 ALA 303 303 303 ALA ALA C . n 
C 1 304 LYS 304 304 304 LYS LYS C . n 
C 1 305 THR 305 305 305 THR THR C . n 
C 1 306 MET 306 306 306 MET MET C . n 
C 1 307 MET 307 307 307 MET MET C . n 
C 1 308 ALA 308 308 308 ALA ALA C . n 
C 1 309 ASP 309 309 309 ASP ASP C . n 
C 1 310 LEU 310 310 310 LEU LEU C . n 
C 1 311 ASP 311 311 311 ASP ASP C . n 
C 1 312 LEU 312 312 312 LEU LEU C . n 
C 1 313 GLY 313 313 313 GLY GLY C . n 
C 1 314 MET 314 314 314 MET MET C . n 
C 1 315 TRP 315 315 315 TRP TRP C . n 
C 1 316 ASN 316 316 316 ASN ASN C . n 
C 1 317 PHE 317 317 317 PHE PHE C . n 
C 1 318 CYS 318 318 318 CYS CYS C . n 
C 1 319 GLY 319 319 319 GLY GLY C . n 
C 1 320 ALA 320 320 320 ALA ALA C . n 
C 1 321 LEU 321 321 321 LEU LEU C . n 
C 1 322 TYR 322 322 322 TYR TYR C . n 
C 1 323 GLY 323 323 323 GLY GLY C . n 
C 1 324 PRO 324 324 324 PRO PRO C . n 
C 1 325 PRO 325 325 325 PRO PRO C . n 
C 1 326 PRO 326 326 326 PRO PRO C . n 
C 1 327 VAL 327 327 327 VAL VAL C . n 
C 1 328 MET 328 328 328 MET MET C . n 
C 1 329 ASP 329 329 329 ASP ASP C . n 
C 1 330 THR 330 330 330 THR THR C . n 
C 1 331 LEU 331 331 331 LEU LEU C . n 
C 1 332 TRP 332 332 332 TRP TRP C . n 
C 1 333 THR 333 333 333 THR THR C . n 
C 1 334 ALA 334 334 334 ALA ALA C . n 
C 1 335 ILE 335 335 335 ILE ILE C . n 
C 1 336 ARG 336 336 336 ARG ARG C . n 
C 1 337 ASP 337 337 337 ASP ASP C . n 
C 1 338 SER 338 338 338 SER SER C . n 
C 1 339 PHE 339 339 339 PHE PHE C . n 
C 1 340 ALA 340 340 340 ALA ALA C . n 
C 1 341 ASP 341 341 341 ASP ASP C . n 
C 1 342 ILE 342 342 342 ILE ILE C . n 
C 1 343 PRO 343 343 343 PRO PRO C . n 
C 1 344 GLY 344 344 344 GLY GLY C . n 
C 1 345 VAL 345 345 345 VAL VAL C . n 
C 1 346 LYS 346 346 346 LYS LYS C . n 
C 1 347 PHE 347 347 347 PHE PHE C . n 
C 1 348 TYR 348 348 348 TYR TYR C . n 
C 1 349 PHE 349 349 349 PHE PHE C . n 
C 1 350 PRO 350 350 350 PRO PRO C . n 
C 1 351 GLU 351 351 351 GLU GLU C . n 
C 1 352 ASP 352 352 352 ASP ASP C . n 
C 1 353 ARG 353 353 353 ARG ARG C . n 
C 1 354 ARG 354 354 354 ARG ARG C . n 
C 1 355 HIS 355 355 355 HIS HIS C . n 
C 1 356 LYS 356 356 356 LYS LYS C . n 
C 1 357 VAL 357 357 357 VAL VAL C . n 
C 1 358 ASP 358 358 358 ASP ASP C . n 
C 1 359 LEU 359 359 359 LEU LEU C . n 
C 1 360 LEU 360 360 360 LEU LEU C . n 
C 1 361 LEU 361 361 361 LEU LEU C . n 
C 1 362 HIS 362 362 362 HIS HIS C . n 
C 1 363 ARG 363 363 363 ARG ARG C . n 
C 1 364 ALA 364 364 364 ALA ALA C . n 
C 1 365 GLU 365 365 365 GLU GLU C . n 
C 1 366 THR 366 366 366 THR THR C . n 
C 1 367 MET 367 367 367 MET MET C . n 
C 1 368 LYS 368 368 368 LYS LYS C . n 
C 1 369 GLY 369 369 369 GLY GLY C . n 
C 1 370 VAL 370 370 370 VAL VAL C . n 
C 1 371 PRO 371 371 371 PRO PRO C . n 
C 1 372 LYS 372 372 372 LYS LYS C . n 
C 1 373 LEU 373 373 373 LEU LEU C . n 
C 1 374 THR 374 374 374 THR THR C . n 
C 1 375 GLU 375 375 375 GLU GLU C . n 
C 1 376 PHE 376 376 376 PHE PHE C . n 
C 1 377 ASN 377 377 377 ASN ASN C . n 
C 1 378 PHE 378 378 378 PHE PHE C . n 
C 1 379 LEU 379 379 379 LEU LEU C . n 
C 1 380 ASN 380 380 380 ASN ASN C . n 
C 1 381 TRP 381 381 381 TRP TRP C . n 
C 1 382 ASP 382 382 382 ASP ASP C . n 
C 1 383 GLY 383 383 383 GLY GLY C . n 
C 1 384 GLY 384 384 384 GLY GLY C . n 
C 1 385 GLY 385 385 385 GLY GLY C . n 
C 1 386 GLY 386 386 386 GLY GLY C . n 
C 1 387 HIS 387 387 387 HIS HIS C . n 
C 1 388 VAL 388 388 388 VAL VAL C . n 
C 1 389 GLY 389 389 389 GLY GLY C . n 
C 1 390 PHE 390 390 390 PHE PHE C . n 
C 1 391 SER 391 391 391 SER SER C . n 
C 1 392 PRO 392 392 392 PRO PRO C . n 
C 1 393 VAL 393 393 393 VAL VAL C . n 
C 1 394 SER 394 394 394 SER SER C . n 
C 1 395 PRO 395 395 395 PRO PRO C . n 
C 1 396 ILE 396 396 396 ILE ILE C . n 
C 1 397 THR 397 397 397 THR THR C . n 
C 1 398 GLY 398 398 398 GLY GLY C . n 
C 1 399 LYS 399 399 399 LYS LYS C . n 
C 1 400 ASP 400 400 400 ASP ASP C . n 
C 1 401 ALA 401 401 401 ALA ALA C . n 
C 1 402 ILE 402 402 402 ILE ILE C . n 
C 1 403 LYS 403 403 403 LYS LYS C . n 
C 1 404 GLN 404 404 404 GLN GLN C . n 
C 1 405 TYR 405 405 405 TYR TYR C . n 
C 1 406 ASN 406 406 406 ASN ASN C . n 
C 1 407 MET 407 407 407 MET MET C . n 
C 1 408 VAL 408 408 408 VAL VAL C . n 
C 1 409 SER 409 409 409 SER SER C . n 
C 1 410 SER 410 410 410 SER SER C . n 
C 1 411 ARG 411 411 411 ARG ARG C . n 
C 1 412 VAL 412 412 412 VAL VAL C . n 
C 1 413 ARG 413 413 413 ARG ARG C . n 
C 1 414 GLU 414 414 414 GLU GLU C . n 
C 1 415 TYR 415 415 415 TYR TYR C . n 
C 1 416 GLY 416 416 416 GLY GLY C . n 
C 1 417 PHE 417 417 417 PHE PHE C . n 
C 1 418 ASP 418 418 418 ASP ASP C . n 
C 1 419 TYR 419 419 419 TYR TYR C . n 
C 1 420 MET 420 420 420 MET MET C . n 
C 1 421 GLY 421 421 421 GLY GLY C . n 
C 1 422 LEU 422 422 422 LEU LEU C . n 
C 1 423 LEU 423 423 423 LEU LEU C . n 
C 1 424 ALA 424 424 424 ALA ALA C . n 
C 1 425 ILE 425 425 425 ILE ILE C . n 
C 1 426 GLY 426 426 426 GLY GLY C . n 
C 1 427 TRP 427 427 427 TRP TRP C . n 
C 1 428 ARG 428 428 428 ARG ARG C . n 
C 1 429 ASP 429 429 429 ASP ASP C . n 
C 1 430 LEU 430 430 430 LEU LEU C . n 
C 1 431 HIS 431 431 431 HIS HIS C . n 
C 1 432 HIS 432 432 432 HIS HIS C . n 
C 1 433 VAL 433 433 433 VAL VAL C . n 
C 1 434 THR 434 434 434 THR THR C . n 
C 1 435 VAL 435 435 435 VAL VAL C . n 
C 1 436 ILE 436 436 436 ILE ILE C . n 
C 1 437 VAL 437 437 437 VAL VAL C . n 
C 1 438 TYR 438 438 438 TYR TYR C . n 
C 1 439 ASP 439 439 439 ASP ASP C . n 
C 1 440 LYS 440 440 440 LYS LYS C . n 
C 1 441 THR 441 441 441 THR THR C . n 
C 1 442 ASP 442 442 442 ASP ASP C . n 
C 1 443 PRO 443 443 443 PRO PRO C . n 
C 1 444 ASP 444 444 444 ASP ASP C . n 
C 1 445 GLU 445 445 445 GLU GLU C . n 
C 1 446 ARG 446 446 446 ARG ARG C . n 
C 1 447 LYS 447 447 447 LYS LYS C . n 
C 1 448 LYS 448 448 448 LYS LYS C . n 
C 1 449 LEU 449 449 449 LEU LEU C . n 
C 1 450 ASP 450 450 450 ASP ASP C . n 
C 1 451 GLU 451 451 451 GLU GLU C . n 
C 1 452 LEU 452 452 452 LEU LEU C . n 
C 1 453 PHE 453 453 453 PHE PHE C . n 
C 1 454 ASN 454 454 454 ASN ASN C . n 
C 1 455 ILE 455 455 455 ILE ILE C . n 
C 1 456 LEU 456 456 456 LEU LEU C . n 
C 1 457 VAL 457 457 457 VAL VAL C . n 
C 1 458 ASP 458 458 458 ASP ASP C . n 
C 1 459 GLU 459 459 459 GLU GLU C . n 
C 1 460 ALA 460 460 460 ALA ALA C . n 
C 1 461 ALA 461 461 461 ALA ALA C . n 
C 1 462 ALA 462 462 462 ALA ALA C . n 
C 1 463 GLU 463 463 463 GLU GLU C . n 
C 1 464 GLY 464 464 464 GLY GLY C . n 
C 1 465 TYR 465 465 465 TYR TYR C . n 
C 1 466 GLY 466 466 466 GLY GLY C . n 
C 1 467 GLU 467 467 467 GLU GLU C . n 
C 1 468 TYR 468 468 468 TYR TYR C . n 
C 1 469 ARG 469 469 469 ARG ARG C . n 
C 1 470 THR 470 470 470 THR THR C . n 
C 1 471 HIS 471 471 471 HIS HIS C . n 
C 1 472 ILE 472 472 472 ILE ILE C . n 
C 1 473 ARG 473 473 473 ARG ARG C . n 
C 1 474 TYR 474 474 474 TYR TYR C . n 
C 1 475 MET 475 475 475 MET MET C . n 
C 1 476 ASP 476 476 476 ASP ASP C . n 
C 1 477 ARG 477 477 477 ARG ARG C . n 
C 1 478 ILE 478 478 478 ILE ILE C . n 
C 1 479 ALA 479 479 479 ALA ALA C . n 
C 1 480 LYS 480 480 480 LYS LYS C . n 
C 1 481 THR 481 481 481 THR THR C . n 
C 1 482 TYR 482 482 482 TYR TYR C . n 
C 1 483 SER 483 483 483 SER SER C . n 
C 1 484 TRP 484 484 484 TRP TRP C . n 
C 1 485 ASN 485 485 485 ASN ASN C . n 
C 1 486 ASP 486 486 486 ASP ASP C . n 
C 1 487 ASN 487 487 487 ASN ASN C . n 
C 1 488 ALA 488 488 488 ALA ALA C . n 
C 1 489 LEU 489 489 489 LEU LEU C . n 
C 1 490 TRP 490 490 490 TRP TRP C . n 
C 1 491 LYS 491 491 491 LYS LYS C . n 
C 1 492 MET 492 492 492 MET MET C . n 
C 1 493 HIS 493 493 493 HIS HIS C . n 
C 1 494 GLU 494 494 494 GLU GLU C . n 
C 1 495 THR 495 495 495 THR THR C . n 
C 1 496 ILE 496 496 496 ILE ILE C . n 
C 1 497 LYS 497 497 497 LYS LYS C . n 
C 1 498 ASP 498 498 498 ASP ASP C . n 
C 1 499 ALA 499 499 499 ALA ALA C . n 
C 1 500 LEU 500 500 500 LEU LEU C . n 
C 1 501 ASP 501 501 501 ASP ASP C . n 
C 1 502 PRO 502 502 502 PRO PRO C . n 
C 1 503 ASN 503 503 503 ASN ASN C . n 
C 1 504 GLY 504 504 504 GLY GLY C . n 
C 1 505 ILE 505 505 505 ILE ILE C . n 
C 1 506 LEU 506 506 506 LEU LEU C . n 
C 1 507 ALA 507 507 507 ALA ALA C . n 
C 1 508 PRO 508 508 508 PRO PRO C . n 
C 1 509 GLY 509 509 509 GLY GLY C . n 
C 1 510 LYS 510 510 510 LYS LYS C . n 
C 1 511 SER 511 511 511 SER SER C . n 
C 1 512 GLY 512 512 512 GLY GLY C . n 
C 1 513 ILE 513 513 513 ILE ILE C . n 
C 1 514 TRP 514 514 514 TRP TRP C . n 
C 1 515 GLY 515 515 515 GLY GLY C . n 
C 1 516 LYS 516 516 516 LYS LYS C . n 
C 1 517 ASN 517 517 517 ASN ASN C . n 
C 1 518 ARG 518 518 518 ARG ARG C . n 
C 1 519 ARG 519 519 519 ARG ARG C . n 
C 1 520 LYS 520 520 ?   ?   ?   C . n 
C 1 521 ALA 521 521 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        FAD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   FAD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 FAD 1   601 601 FAD FAD A . 
E 2 FAD 1   601 601 FAD FAD B . 
F 2 FAD 1   601 601 FAD FAD C . 
G 3 HOH 1   701 45  HOH HOH A . 
G 3 HOH 2   702 109 HOH HOH A . 
G 3 HOH 3   703 99  HOH HOH A . 
G 3 HOH 4   704 237 HOH HOH A . 
G 3 HOH 5   705 66  HOH HOH A . 
G 3 HOH 6   706 74  HOH HOH A . 
G 3 HOH 7   707 67  HOH HOH A . 
G 3 HOH 8   708 165 HOH HOH A . 
G 3 HOH 9   709 175 HOH HOH A . 
G 3 HOH 10  710 55  HOH HOH A . 
G 3 HOH 11  711 85  HOH HOH A . 
G 3 HOH 12  712 68  HOH HOH A . 
G 3 HOH 13  713 127 HOH HOH A . 
G 3 HOH 14  714 2   HOH HOH A . 
G 3 HOH 15  715 42  HOH HOH A . 
G 3 HOH 16  716 183 HOH HOH A . 
G 3 HOH 17  717 88  HOH HOH A . 
G 3 HOH 18  718 101 HOH HOH A . 
G 3 HOH 19  719 70  HOH HOH A . 
G 3 HOH 20  720 148 HOH HOH A . 
G 3 HOH 21  721 59  HOH HOH A . 
G 3 HOH 22  722 206 HOH HOH A . 
G 3 HOH 23  723 171 HOH HOH A . 
G 3 HOH 24  724 100 HOH HOH A . 
G 3 HOH 25  725 21  HOH HOH A . 
G 3 HOH 26  726 50  HOH HOH A . 
G 3 HOH 27  727 118 HOH HOH A . 
G 3 HOH 28  728 110 HOH HOH A . 
G 3 HOH 29  729 30  HOH HOH A . 
G 3 HOH 30  730 60  HOH HOH A . 
G 3 HOH 31  731 189 HOH HOH A . 
G 3 HOH 32  732 46  HOH HOH A . 
G 3 HOH 33  733 139 HOH HOH A . 
G 3 HOH 34  734 16  HOH HOH A . 
G 3 HOH 35  735 89  HOH HOH A . 
G 3 HOH 36  736 39  HOH HOH A . 
G 3 HOH 37  737 31  HOH HOH A . 
G 3 HOH 38  738 199 HOH HOH A . 
G 3 HOH 39  739 97  HOH HOH A . 
G 3 HOH 40  740 138 HOH HOH A . 
G 3 HOH 41  741 11  HOH HOH A . 
G 3 HOH 42  742 132 HOH HOH A . 
G 3 HOH 43  743 43  HOH HOH A . 
G 3 HOH 44  744 82  HOH HOH A . 
G 3 HOH 45  745 102 HOH HOH A . 
G 3 HOH 46  746 27  HOH HOH A . 
G 3 HOH 47  747 26  HOH HOH A . 
G 3 HOH 48  748 129 HOH HOH A . 
G 3 HOH 49  749 152 HOH HOH A . 
G 3 HOH 50  750 76  HOH HOH A . 
G 3 HOH 51  751 10  HOH HOH A . 
G 3 HOH 52  752 145 HOH HOH A . 
G 3 HOH 53  753 65  HOH HOH A . 
G 3 HOH 54  754 35  HOH HOH A . 
G 3 HOH 55  755 208 HOH HOH A . 
G 3 HOH 56  756 134 HOH HOH A . 
G 3 HOH 57  757 232 HOH HOH A . 
G 3 HOH 58  758 156 HOH HOH A . 
G 3 HOH 59  759 154 HOH HOH A . 
G 3 HOH 60  760 106 HOH HOH A . 
G 3 HOH 61  761 33  HOH HOH A . 
G 3 HOH 62  762 20  HOH HOH A . 
G 3 HOH 63  763 112 HOH HOH A . 
G 3 HOH 64  764 236 HOH HOH A . 
G 3 HOH 65  765 48  HOH HOH A . 
G 3 HOH 66  766 61  HOH HOH A . 
G 3 HOH 67  767 8   HOH HOH A . 
G 3 HOH 68  768 32  HOH HOH A . 
G 3 HOH 69  769 123 HOH HOH A . 
G 3 HOH 70  770 15  HOH HOH A . 
G 3 HOH 71  771 54  HOH HOH A . 
G 3 HOH 72  772 120 HOH HOH A . 
G 3 HOH 73  773 141 HOH HOH A . 
G 3 HOH 74  774 164 HOH HOH A . 
G 3 HOH 75  775 186 HOH HOH A . 
G 3 HOH 76  776 4   HOH HOH A . 
G 3 HOH 77  777 71  HOH HOH A . 
G 3 HOH 78  778 151 HOH HOH A . 
G 3 HOH 79  779 116 HOH HOH A . 
G 3 HOH 80  780 80  HOH HOH A . 
G 3 HOH 81  781 150 HOH HOH A . 
G 3 HOH 82  782 136 HOH HOH A . 
G 3 HOH 83  783 133 HOH HOH A . 
G 3 HOH 84  784 22  HOH HOH A . 
G 3 HOH 85  785 153 HOH HOH A . 
G 3 HOH 86  786 126 HOH HOH A . 
G 3 HOH 87  787 86  HOH HOH A . 
G 3 HOH 88  788 130 HOH HOH A . 
G 3 HOH 89  789 96  HOH HOH A . 
G 3 HOH 90  790 113 HOH HOH A . 
G 3 HOH 91  791 104 HOH HOH A . 
G 3 HOH 92  792 192 HOH HOH A . 
G 3 HOH 93  793 142 HOH HOH A . 
G 3 HOH 94  794 181 HOH HOH A . 
G 3 HOH 95  795 227 HOH HOH A . 
G 3 HOH 96  796 231 HOH HOH A . 
G 3 HOH 97  797 209 HOH HOH A . 
G 3 HOH 98  798 235 HOH HOH A . 
G 3 HOH 99  799 238 HOH HOH A . 
G 3 HOH 100 800 47  HOH HOH A . 
G 3 HOH 101 801 203 HOH HOH A . 
G 3 HOH 102 802 217 HOH HOH A . 
G 3 HOH 103 803 202 HOH HOH A . 
G 3 HOH 104 804 200 HOH HOH A . 
G 3 HOH 105 805 128 HOH HOH A . 
G 3 HOH 106 806 210 HOH HOH A . 
G 3 HOH 107 807 223 HOH HOH A . 
G 3 HOH 108 808 216 HOH HOH A . 
G 3 HOH 109 809 213 HOH HOH A . 
G 3 HOH 110 810 220 HOH HOH A . 
G 3 HOH 111 811 214 HOH HOH A . 
G 3 HOH 112 812 215 HOH HOH A . 
G 3 HOH 113 813 211 HOH HOH A . 
H 3 HOH 1   701 204 HOH HOH B . 
H 3 HOH 2   702 194 HOH HOH B . 
H 3 HOH 3   703 177 HOH HOH B . 
H 3 HOH 4   704 64  HOH HOH B . 
H 3 HOH 5   705 174 HOH HOH B . 
H 3 HOH 6   706 178 HOH HOH B . 
H 3 HOH 7   707 78  HOH HOH B . 
H 3 HOH 8   708 51  HOH HOH B . 
H 3 HOH 9   709 125 HOH HOH B . 
H 3 HOH 10  710 190 HOH HOH B . 
H 3 HOH 11  711 34  HOH HOH B . 
H 3 HOH 12  712 147 HOH HOH B . 
H 3 HOH 13  713 94  HOH HOH B . 
H 3 HOH 14  714 137 HOH HOH B . 
H 3 HOH 15  715 83  HOH HOH B . 
H 3 HOH 16  716 162 HOH HOH B . 
H 3 HOH 17  717 163 HOH HOH B . 
H 3 HOH 18  718 91  HOH HOH B . 
H 3 HOH 19  719 173 HOH HOH B . 
H 3 HOH 20  720 111 HOH HOH B . 
H 3 HOH 21  721 14  HOH HOH B . 
H 3 HOH 22  722 98  HOH HOH B . 
H 3 HOH 23  723 49  HOH HOH B . 
H 3 HOH 24  724 56  HOH HOH B . 
H 3 HOH 25  725 77  HOH HOH B . 
H 3 HOH 26  726 84  HOH HOH B . 
H 3 HOH 27  727 114 HOH HOH B . 
H 3 HOH 28  728 176 HOH HOH B . 
H 3 HOH 29  729 198 HOH HOH B . 
H 3 HOH 30  730 131 HOH HOH B . 
H 3 HOH 31  731 81  HOH HOH B . 
H 3 HOH 32  732 18  HOH HOH B . 
H 3 HOH 33  733 196 HOH HOH B . 
H 3 HOH 34  734 143 HOH HOH B . 
H 3 HOH 35  735 117 HOH HOH B . 
H 3 HOH 36  736 172 HOH HOH B . 
H 3 HOH 37  737 44  HOH HOH B . 
H 3 HOH 38  738 92  HOH HOH B . 
H 3 HOH 39  739 122 HOH HOH B . 
H 3 HOH 40  740 7   HOH HOH B . 
H 3 HOH 41  741 105 HOH HOH B . 
H 3 HOH 42  742 25  HOH HOH B . 
H 3 HOH 43  743 36  HOH HOH B . 
H 3 HOH 44  744 149 HOH HOH B . 
H 3 HOH 45  745 159 HOH HOH B . 
H 3 HOH 46  746 158 HOH HOH B . 
H 3 HOH 47  747 179 HOH HOH B . 
H 3 HOH 48  748 195 HOH HOH B . 
H 3 HOH 49  749 140 HOH HOH B . 
H 3 HOH 50  750 13  HOH HOH B . 
H 3 HOH 51  751 75  HOH HOH B . 
H 3 HOH 52  752 184 HOH HOH B . 
H 3 HOH 53  753 29  HOH HOH B . 
H 3 HOH 54  754 241 HOH HOH B . 
H 3 HOH 55  755 108 HOH HOH B . 
H 3 HOH 56  756 63  HOH HOH B . 
H 3 HOH 57  757 169 HOH HOH B . 
H 3 HOH 58  758 90  HOH HOH B . 
H 3 HOH 59  759 180 HOH HOH B . 
H 3 HOH 60  760 119 HOH HOH B . 
H 3 HOH 61  761 144 HOH HOH B . 
H 3 HOH 62  762 167 HOH HOH B . 
H 3 HOH 63  763 157 HOH HOH B . 
H 3 HOH 64  764 146 HOH HOH B . 
H 3 HOH 65  765 57  HOH HOH B . 
H 3 HOH 66  766 103 HOH HOH B . 
H 3 HOH 67  767 197 HOH HOH B . 
H 3 HOH 68  768 218 HOH HOH B . 
H 3 HOH 69  769 239 HOH HOH B . 
H 3 HOH 70  770 205 HOH HOH B . 
H 3 HOH 71  771 207 HOH HOH B . 
H 3 HOH 72  772 222 HOH HOH B . 
H 3 HOH 73  773 224 HOH HOH B . 
H 3 HOH 74  774 225 HOH HOH B . 
H 3 HOH 75  775 242 HOH HOH B . 
H 3 HOH 76  776 219 HOH HOH B . 
I 3 HOH 1   701 166 HOH HOH C . 
I 3 HOH 2   702 52  HOH HOH C . 
I 3 HOH 3   703 155 HOH HOH C . 
I 3 HOH 4   704 37  HOH HOH C . 
I 3 HOH 5   705 95  HOH HOH C . 
I 3 HOH 6   706 17  HOH HOH C . 
I 3 HOH 7   707 28  HOH HOH C . 
I 3 HOH 8   708 1   HOH HOH C . 
I 3 HOH 9   709 58  HOH HOH C . 
I 3 HOH 10  710 124 HOH HOH C . 
I 3 HOH 11  711 5   HOH HOH C . 
I 3 HOH 12  712 3   HOH HOH C . 
I 3 HOH 13  713 73  HOH HOH C . 
I 3 HOH 14  714 12  HOH HOH C . 
I 3 HOH 15  715 79  HOH HOH C . 
I 3 HOH 16  716 38  HOH HOH C . 
I 3 HOH 17  717 188 HOH HOH C . 
I 3 HOH 18  718 201 HOH HOH C . 
I 3 HOH 19  719 87  HOH HOH C . 
I 3 HOH 20  720 161 HOH HOH C . 
I 3 HOH 21  721 69  HOH HOH C . 
I 3 HOH 22  722 187 HOH HOH C . 
I 3 HOH 23  723 168 HOH HOH C . 
I 3 HOH 24  724 62  HOH HOH C . 
I 3 HOH 25  725 19  HOH HOH C . 
I 3 HOH 26  726 182 HOH HOH C . 
I 3 HOH 27  727 107 HOH HOH C . 
I 3 HOH 28  728 23  HOH HOH C . 
I 3 HOH 29  729 72  HOH HOH C . 
I 3 HOH 30  730 135 HOH HOH C . 
I 3 HOH 31  731 115 HOH HOH C . 
I 3 HOH 32  732 93  HOH HOH C . 
I 3 HOH 33  733 160 HOH HOH C . 
I 3 HOH 34  734 170 HOH HOH C . 
I 3 HOH 35  735 9   HOH HOH C . 
I 3 HOH 36  736 24  HOH HOH C . 
I 3 HOH 37  737 53  HOH HOH C . 
I 3 HOH 38  738 40  HOH HOH C . 
I 3 HOH 39  739 191 HOH HOH C . 
I 3 HOH 40  740 6   HOH HOH C . 
I 3 HOH 41  741 193 HOH HOH C . 
I 3 HOH 42  742 226 HOH HOH C . 
I 3 HOH 43  743 41  HOH HOH C . 
I 3 HOH 44  744 121 HOH HOH C . 
I 3 HOH 45  745 240 HOH HOH C . 
I 3 HOH 46  746 185 HOH HOH C . 
I 3 HOH 47  747 228 HOH HOH C . 
I 3 HOH 48  748 229 HOH HOH C . 
I 3 HOH 49  749 221 HOH HOH C . 
I 3 HOH 50  750 212 HOH HOH C . 
I 3 HOH 51  751 234 HOH HOH C . 
I 3 HOH 52  752 233 HOH HOH C . 
I 3 HOH 53  753 230 HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0403 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8S7S 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     90.804 
_cell.length_a_esd                 ? 
_cell.length_b                     144.145 
_cell.length_b_esd                 ? 
_cell.length_c                     289.452 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8S7S 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8S7S 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.71 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          54.65 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          EVAPORATION 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'G4 condition of the morpheus crystal screen by Hampton Research' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 2M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-03-31 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.967700 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE MASSIF-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.967700 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   MASSIF-1 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8S7S 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.50 
_reflns.d_resolution_low                               64.60 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     66056 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                22.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.5 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.98 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.207 
_reflns.pdbx_Rpim_I_all                                0.043 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.202 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.50 
_reflns_shell.d_res_low                                     2.56 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           103437 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4381 
_reflns_shell.percent_possible_obs                          100.0 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               23.6 
_reflns_shell.pdbx_chi_squared                              0.91 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     1.2 
_reflns_shell.pdbx_Rrim_I_all                               3.346 
_reflns_shell.pdbx_Rpim_I_all                               0.686 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.605 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  3.274 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            2.80 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            -0.00 
_refine.aniso_B[2][2]                            -0.13 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            -2.67 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               56.371 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.955 
_refine.correlation_coeff_Fo_to_Fc_free          0.922 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8S7S 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.50 
_refine.ls_d_res_low                             64.60 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     62822 
_refine.ls_number_reflns_R_free                  3182 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.98 
_refine.ls_percent_reflns_R_free                 4.8 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.19494 
_refine.ls_R_factor_R_free                       0.25173 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.19200 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.495 
_refine.pdbx_overall_ESU_R_Free                  0.287 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             10.276 
_refine.overall_SU_ML                            0.216 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.50 
_refine_hist.d_res_low                        64.60 
_refine_hist.number_atoms_solvent             242 
_refine_hist.number_atoms_total               12635 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        12234 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         159 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  12756 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  11637 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.515  1.651  17394 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.506  1.568  26823 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 7.820  5.000  1551  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 8.265  5.000  78    ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 16.184 10.000 1971  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.070  0.200  1824  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020  14928 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  2961  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 5.161  5.556  6213  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.161  5.556  6213  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 7.339  9.994  7761  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 7.339  9.994  7762  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.725  6.001  6543  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.725  6.000  6540  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 8.366  10.839 9634  ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 10.365 54.39  14578 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 10.367 54.41  14563 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.500 
_refine_ls_shell.d_res_low                        2.565 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             224 
_refine_ls_shell.number_reflns_R_work             4605 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.582 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.607 
# 
_struct.entry_id                     8S7S 
_struct.title                        'Vanillyl-alcohol dehydrogenase from Marinicaulis flavus: P151G mutant' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8S7S 
_struct_keywords.text            'FAD, flavin, oxidase, alcohol, enzyme mechanism, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A2S7K3M2_9PROT 
_struct_ref.pdbx_db_accession          A0A2S7K3M2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MAAPLPEGVSAEAMSSALDRFARIVGADWVFTEDKITPYEDPYTISNDETEHRPYAAVAPASTEEVQEIVRVANEFGVPL
WPVSRGKNFAYGGAAPVMSGTVVLDMNRMNRILEVNEEFGYALVEPGVSYFELYDYIQEKGLKLWIDVPDPGWGSVVGNA
LDHGIGYTPYGDHFAMQCGMEVVLPNGEVVRTGMGAMPGNNTWQLFKYGYGPYVDGIFSQSNFGVVTKMGIWLMPEPAGY
RPYLITFENEDDIETVTERLRPLKVAGVIQNGATVRSLVLDAAITRTKSQYYDGDGPIPPSVAKTMMADLDLGMWNFCGA
LYGPPPVMDTLWTAIRDSFADIPGVKFYFPEDRRHKVDLLLHRAETMKGVPKLTEFNFLNWDGGGGHVGFSPVSPITGKD
AIKQYNMVSSRVREYGFDYMGLLAIGWRDLHHVTVIVYDKTDPDERKKLDELFNILVDEAAAEGYGEYRTHIRYMDRIAK
TYSWNDNALWKMHETIKDALDPNGILAPGKSGIWGKNRRKA
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8S7S A 1 ? 521 ? A0A2S7K3M2 1 ? 521 ? 1 521 
2 1 8S7S B 1 ? 521 ? A0A2S7K3M2 1 ? 521 ? 1 521 
3 1 8S7S C 1 ? 521 ? A0A2S7K3M2 1 ? 521 ? 1 521 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8S7S GLY A 151 ? UNP A0A2S7K3M2 PRO 151 'engineered mutation' 151 1 
2 8S7S GLY B 151 ? UNP A0A2S7K3M2 PRO 151 'engineered mutation' 151 2 
3 8S7S GLY C 151 ? UNP A0A2S7K3M2 PRO 151 'engineered mutation' 151 3 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 9890  ? 
1 MORE         -81   ? 
1 'SSA (A^2)'  34520 ? 
2 'ABSA (A^2)' 9910  ? 
2 MORE         -84   ? 
2 'SSA (A^2)'  34340 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1,2 A,D,G       
2 1   B,C,E,F,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z   1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000 
2 'crystal symmetry operation' 4_555 x,-y,-z 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 10  ? GLY A 26  ? SER A 10  GLY A 26  1 ? 17 
HELX_P HELX_P2  AA2 THR A 32  ? THR A 37  ? THR A 32  THR A 37  5 ? 6  
HELX_P HELX_P3  AA3 SER A 62  ? PHE A 76  ? SER A 62  PHE A 76  1 ? 15 
HELX_P HELX_P4  AA4 SER A 129 ? LYS A 140 ? SER A 129 LYS A 140 1 ? 12 
HELX_P HELX_P5  AA5 SER A 155 ? ASP A 162 ? SER A 155 ASP A 162 1 ? 8  
HELX_P HELX_P6  AA6 HIS A 173 ? ALA A 175 ? HIS A 173 ALA A 175 5 ? 3  
HELX_P HELX_P7  AA7 GLY A 193 ? MET A 197 ? GLY A 193 MET A 197 5 ? 5  
HELX_P HELX_P8  AA8 VAL A 214 ? SER A 219 ? VAL A 214 SER A 219 5 ? 6  
HELX_P HELX_P9  AA9 ASN A 249 ? ASP A 251 ? ASN A 249 ASP A 251 5 ? 3  
HELX_P HELX_P10 AB1 ASP A 252 ? ALA A 266 ? ASP A 252 ALA A 266 1 ? 15 
HELX_P HELX_P11 AB2 LEU A 278 ? ALA A 283 ? LEU A 278 ALA A 283 1 ? 6  
HELX_P HELX_P12 AB3 THR A 287 ? TYR A 291 ? THR A 287 TYR A 291 5 ? 5  
HELX_P HELX_P13 AB4 PRO A 299 ? ASP A 311 ? PRO A 299 ASP A 311 1 ? 13 
HELX_P HELX_P14 AB5 PRO A 324 ? SER A 338 ? PRO A 324 SER A 338 1 ? 15 
HELX_P HELX_P15 AB6 PHE A 349 ? ARG A 353 ? PHE A 349 ARG A 353 5 ? 5  
HELX_P HELX_P16 AB7 ASP A 358 ? MET A 367 ? ASP A 358 MET A 367 1 ? 10 
HELX_P HELX_P17 AB8 LEU A 373 ? TRP A 381 ? LEU A 373 TRP A 381 5 ? 9  
HELX_P HELX_P18 AB9 THR A 397 ? TYR A 415 ? THR A 397 TYR A 415 1 ? 19 
HELX_P HELX_P19 AC1 ASP A 442 ? ALA A 462 ? ASP A 442 ALA A 462 1 ? 21 
HELX_P HELX_P20 AC2 HIS A 471 ? ARG A 473 ? HIS A 471 ARG A 473 5 ? 3  
HELX_P HELX_P21 AC3 TYR A 474 ? LYS A 480 ? TYR A 474 LYS A 480 1 ? 7  
HELX_P HELX_P22 AC4 SER A 483 ? ASP A 501 ? SER A 483 ASP A 501 1 ? 19 
HELX_P HELX_P23 AC5 GLY A 509 ? ILE A 513 ? GLY A 509 ILE A 513 5 ? 5  
HELX_P HELX_P24 AC6 SER B 10  ? GLY B 26  ? SER B 10  GLY B 26  1 ? 17 
HELX_P HELX_P25 AC7 ILE B 36  ? GLU B 40  ? ILE B 36  GLU B 40  5 ? 5  
HELX_P HELX_P26 AC8 SER B 62  ? GLY B 77  ? SER B 62  GLY B 77  1 ? 16 
HELX_P HELX_P27 AC9 SER B 129 ? LYS B 140 ? SER B 129 LYS B 140 1 ? 12 
HELX_P HELX_P28 AD1 SER B 155 ? ASP B 162 ? SER B 155 ASP B 162 1 ? 8  
HELX_P HELX_P29 AD2 ASP B 172 ? ALA B 175 ? ASP B 172 ALA B 175 5 ? 4  
HELX_P HELX_P30 AD3 GLY B 193 ? MET B 197 ? GLY B 193 MET B 197 5 ? 5  
HELX_P HELX_P31 AD4 VAL B 214 ? SER B 219 ? VAL B 214 SER B 219 5 ? 6  
HELX_P HELX_P32 AD5 ASN B 249 ? ASP B 251 ? ASN B 249 ASP B 251 5 ? 3  
HELX_P HELX_P33 AD6 ASP B 252 ? ALA B 266 ? ASP B 252 ALA B 266 1 ? 15 
HELX_P HELX_P34 AD7 LEU B 278 ? ALA B 283 ? LEU B 278 ALA B 283 1 ? 6  
HELX_P HELX_P35 AD8 THR B 287 ? TYR B 291 ? THR B 287 TYR B 291 5 ? 5  
HELX_P HELX_P36 AD9 PRO B 299 ? ASP B 311 ? PRO B 299 ASP B 311 1 ? 13 
HELX_P HELX_P37 AE1 PRO B 324 ? SER B 338 ? PRO B 324 SER B 338 1 ? 15 
HELX_P HELX_P38 AE2 PHE B 349 ? ARG B 353 ? PHE B 349 ARG B 353 5 ? 5  
HELX_P HELX_P39 AE3 ASP B 358 ? MET B 367 ? ASP B 358 MET B 367 1 ? 10 
HELX_P HELX_P40 AE4 LEU B 373 ? TRP B 381 ? LEU B 373 TRP B 381 5 ? 9  
HELX_P HELX_P41 AE5 THR B 397 ? TYR B 415 ? THR B 397 TYR B 415 1 ? 19 
HELX_P HELX_P42 AE6 ASP B 442 ? ALA B 462 ? ASP B 442 ALA B 462 1 ? 21 
HELX_P HELX_P43 AE7 HIS B 471 ? ARG B 473 ? HIS B 471 ARG B 473 5 ? 3  
HELX_P HELX_P44 AE8 TYR B 474 ? LYS B 480 ? TYR B 474 LYS B 480 1 ? 7  
HELX_P HELX_P45 AE9 SER B 483 ? ASP B 501 ? SER B 483 ASP B 501 1 ? 19 
HELX_P HELX_P46 AF1 GLY B 509 ? ILE B 513 ? GLY B 509 ILE B 513 5 ? 5  
HELX_P HELX_P47 AF2 GLY B 515 ? ARG B 519 ? GLY B 515 ARG B 519 5 ? 5  
HELX_P HELX_P48 AF3 SER C 10  ? GLY C 26  ? SER C 10  GLY C 26  1 ? 17 
HELX_P HELX_P49 AF4 THR C 32  ? GLU C 40  ? THR C 32  GLU C 40  5 ? 9  
HELX_P HELX_P50 AF5 SER C 62  ? PHE C 76  ? SER C 62  PHE C 76  1 ? 15 
HELX_P HELX_P51 AF6 SER C 129 ? LYS C 140 ? SER C 129 LYS C 140 1 ? 12 
HELX_P HELX_P52 AF7 SER C 155 ? ASP C 162 ? SER C 155 ASP C 162 1 ? 8  
HELX_P HELX_P53 AF8 HIS C 173 ? ALA C 175 ? HIS C 173 ALA C 175 5 ? 3  
HELX_P HELX_P54 AF9 GLY C 193 ? MET C 197 ? GLY C 193 MET C 197 5 ? 5  
HELX_P HELX_P55 AG1 VAL C 214 ? SER C 219 ? VAL C 214 SER C 219 5 ? 6  
HELX_P HELX_P56 AG2 ASP C 251 ? ALA C 266 ? ASP C 251 ALA C 266 1 ? 16 
HELX_P HELX_P57 AG3 LEU C 278 ? ALA C 283 ? LEU C 278 ALA C 283 1 ? 6  
HELX_P HELX_P58 AG4 THR C 287 ? TYR C 291 ? THR C 287 TYR C 291 5 ? 5  
HELX_P HELX_P59 AG5 PRO C 299 ? ASP C 311 ? PRO C 299 ASP C 311 1 ? 13 
HELX_P HELX_P60 AG6 PRO C 324 ? ALA C 340 ? PRO C 324 ALA C 340 1 ? 17 
HELX_P HELX_P61 AG7 PHE C 349 ? ARG C 353 ? PHE C 349 ARG C 353 5 ? 5  
HELX_P HELX_P62 AG8 ASP C 358 ? MET C 367 ? ASP C 358 MET C 367 1 ? 10 
HELX_P HELX_P63 AG9 LEU C 373 ? GLY C 384 ? LEU C 373 GLY C 384 5 ? 12 
HELX_P HELX_P64 AH1 THR C 397 ? TYR C 415 ? THR C 397 TYR C 415 1 ? 19 
HELX_P HELX_P65 AH2 ASP C 442 ? GLU C 463 ? ASP C 442 GLU C 463 1 ? 22 
HELX_P HELX_P66 AH3 HIS C 471 ? ARG C 473 ? HIS C 471 ARG C 473 5 ? 3  
HELX_P HELX_P67 AH4 TYR C 474 ? THR C 481 ? TYR C 474 THR C 481 1 ? 8  
HELX_P HELX_P68 AH5 SER C 483 ? ASP C 501 ? SER C 483 ASP C 501 1 ? 19 
HELX_P HELX_P69 AH6 GLY C 509 ? ILE C 513 ? GLY C 509 ILE C 513 5 ? 5  
HELX_P HELX_P70 AH7 GLY C 515 ? ARG C 519 ? GLY C 515 ARG C 519 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
AA4 ? 7 ? 
AA5 ? 7 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 7 ? 
AA9 ? 7 ? 
AB1 ? 4 ? 
AB2 ? 5 ? 
AB3 ? 2 ? 
AB4 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA5 6 7 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 6 7 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB1 3 4 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB4 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 30  ? PHE A 31  ? VAL A 30  PHE A 31  
AA1 2 ALA A 56  ? VAL A 58  ? ALA A 56  VAL A 58  
AA1 3 VAL A 102 ? ASP A 105 ? VAL A 102 ASP A 105 
AA1 4 LEU A 80  ? VAL A 83  ? LEU A 80  VAL A 83  
AA2 1 ILE A 112 ? ASN A 116 ? ILE A 112 ASN A 116 
AA2 2 TYR A 121 ? VAL A 124 ? TYR A 121 VAL A 124 
AA2 3 VAL A 225 ? TRP A 232 ? VAL A 225 TRP A 232 
AA2 4 GLN A 177 ? VAL A 183 ? GLN A 177 VAL A 183 
AA2 5 VAL A 189 ? ARG A 191 ? VAL A 189 ARG A 191 
AA3 1 LEU A 144 ? TRP A 145 ? LEU A 144 TRP A 145 
AA3 2 MET A 234 ? PRO A 235 ? MET A 234 PRO A 235 
AA4 1 LYS A 346 ? TYR A 348 ? LYS A 346 TYR A 348 
AA4 2 TYR A 240 ? PHE A 247 ? TYR A 240 PHE A 247 
AA4 3 TRP A 315 ? TYR A 322 ? TRP A 315 TYR A 322 
AA4 4 ALA A 273 ? SER A 277 ? ALA A 273 SER A 277 
AA4 5 MET A 420 ? ILE A 425 ? MET A 420 ILE A 425 
AA4 6 ASP A 429 ? TYR A 438 ? ASP A 429 TYR A 438 
AA4 7 GLY A 386 ? PHE A 390 ? GLY A 386 PHE A 390 
AA5 1 LYS A 346 ? TYR A 348 ? LYS A 346 TYR A 348 
AA5 2 TYR A 240 ? PHE A 247 ? TYR A 240 PHE A 247 
AA5 3 TRP A 315 ? TYR A 322 ? TRP A 315 TYR A 322 
AA5 4 ALA A 273 ? SER A 277 ? ALA A 273 SER A 277 
AA5 5 MET A 420 ? ILE A 425 ? MET A 420 ILE A 425 
AA5 6 ASP A 429 ? TYR A 438 ? ASP A 429 TYR A 438 
AA5 7 VAL A 393 ? PRO A 395 ? VAL A 393 PRO A 395 
AA6 1 VAL B 30  ? PHE B 31  ? VAL B 30  PHE B 31  
AA6 2 ALA B 57  ? VAL B 58  ? ALA B 57  VAL B 58  
AA6 3 VAL B 102 ? ASP B 105 ? VAL B 102 ASP B 105 
AA6 4 LEU B 80  ? VAL B 83  ? LEU B 80  VAL B 83  
AA7 1 ILE B 112 ? ASN B 116 ? ILE B 112 ASN B 116 
AA7 2 TYR B 121 ? VAL B 124 ? TYR B 121 VAL B 124 
AA7 3 VAL B 225 ? TRP B 232 ? VAL B 225 TRP B 232 
AA7 4 GLN B 177 ? VAL B 183 ? GLN B 177 VAL B 183 
AA7 5 VAL B 189 ? ARG B 191 ? VAL B 189 ARG B 191 
AA8 1 LYS B 346 ? TYR B 348 ? LYS B 346 TYR B 348 
AA8 2 TYR B 240 ? PHE B 247 ? TYR B 240 PHE B 247 
AA8 3 TRP B 315 ? TYR B 322 ? TRP B 315 TYR B 322 
AA8 4 ALA B 273 ? SER B 277 ? ALA B 273 SER B 277 
AA8 5 MET B 420 ? ILE B 425 ? MET B 420 ILE B 425 
AA8 6 ASP B 429 ? TYR B 438 ? ASP B 429 TYR B 438 
AA8 7 GLY B 386 ? PHE B 390 ? GLY B 386 PHE B 390 
AA9 1 LYS B 346 ? TYR B 348 ? LYS B 346 TYR B 348 
AA9 2 TYR B 240 ? PHE B 247 ? TYR B 240 PHE B 247 
AA9 3 TRP B 315 ? TYR B 322 ? TRP B 315 TYR B 322 
AA9 4 ALA B 273 ? SER B 277 ? ALA B 273 SER B 277 
AA9 5 MET B 420 ? ILE B 425 ? MET B 420 ILE B 425 
AA9 6 ASP B 429 ? TYR B 438 ? ASP B 429 TYR B 438 
AA9 7 VAL B 393 ? PRO B 395 ? VAL B 393 PRO B 395 
AB1 1 VAL C 30  ? PHE C 31  ? VAL C 30  PHE C 31  
AB1 2 PRO C 54  ? VAL C 58  ? PRO C 54  VAL C 58  
AB1 3 THR C 101 ? ASP C 105 ? THR C 101 ASP C 105 
AB1 4 LEU C 80  ? VAL C 83  ? LEU C 80  VAL C 83  
AB2 1 ILE C 112 ? ASN C 116 ? ILE C 112 ASN C 116 
AB2 2 TYR C 121 ? VAL C 124 ? TYR C 121 VAL C 124 
AB2 3 VAL C 225 ? TRP C 232 ? VAL C 225 TRP C 232 
AB2 4 GLN C 177 ? VAL C 183 ? GLN C 177 VAL C 183 
AB2 5 VAL C 189 ? ARG C 191 ? VAL C 189 ARG C 191 
AB3 1 LEU C 144 ? TRP C 145 ? LEU C 144 TRP C 145 
AB3 2 MET C 234 ? PRO C 235 ? MET C 234 PRO C 235 
AB4 1 LYS C 346 ? TYR C 348 ? LYS C 346 TYR C 348 
AB4 2 TYR C 240 ? PHE C 247 ? TYR C 240 PHE C 247 
AB4 3 TRP C 315 ? TYR C 322 ? TRP C 315 TYR C 322 
AB4 4 ALA C 273 ? SER C 277 ? ALA C 273 SER C 277 
AB4 5 MET C 420 ? ILE C 425 ? MET C 420 ILE C 425 
AB4 6 LEU C 430 ? TYR C 438 ? LEU C 430 TYR C 438 
AB4 7 GLY C 386 ? PHE C 390 ? GLY C 386 PHE C 390 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 31  ? N PHE A 31  O ALA A 57  ? O ALA A 57  
AA1 2 3 N VAL A 58  ? N VAL A 58  O ASP A 105 ? O ASP A 105 
AA1 3 4 O LEU A 104 ? O LEU A 104 N VAL A 83  ? N VAL A 83  
AA2 1 2 N GLU A 114 ? N GLU A 114 O LEU A 123 ? O LEU A 123 
AA2 2 3 N VAL A 124 ? N VAL A 124 O MET A 229 ? O MET A 229 
AA2 3 4 O VAL A 225 ? O VAL A 225 N VAL A 183 ? N VAL A 183 
AA2 4 5 N VAL A 182 ? N VAL A 182 O VAL A 190 ? O VAL A 190 
AA3 1 2 N TRP A 145 ? N TRP A 145 O MET A 234 ? O MET A 234 
AA4 1 2 O TYR A 348 ? O TYR A 348 N LEU A 244 ? N LEU A 244 
AA4 2 3 N ILE A 245 ? N ILE A 245 O PHE A 317 ? O PHE A 317 
AA4 3 4 O ASN A 316 ? O ASN A 316 N ARG A 276 ? N ARG A 276 
AA4 4 5 N SER A 277 ? N SER A 277 O GLY A 421 ? O GLY A 421 
AA4 5 6 N ALA A 424 ? N ALA A 424 O HIS A 431 ? O HIS A 431 
AA4 6 7 O ILE A 436 ? O ILE A 436 N VAL A 388 ? N VAL A 388 
AA5 1 2 O TYR A 348 ? O TYR A 348 N LEU A 244 ? N LEU A 244 
AA5 2 3 N ILE A 245 ? N ILE A 245 O PHE A 317 ? O PHE A 317 
AA5 3 4 O ASN A 316 ? O ASN A 316 N ARG A 276 ? N ARG A 276 
AA5 4 5 N SER A 277 ? N SER A 277 O GLY A 421 ? O GLY A 421 
AA5 5 6 N ALA A 424 ? N ALA A 424 O HIS A 431 ? O HIS A 431 
AA5 6 7 O LEU A 430 ? O LEU A 430 N SER A 394 ? N SER A 394 
AA6 1 2 N PHE B 31  ? N PHE B 31  O ALA B 57  ? O ALA B 57  
AA6 2 3 N VAL B 58  ? N VAL B 58  O VAL B 103 ? O VAL B 103 
AA6 3 4 O LEU B 104 ? O LEU B 104 N VAL B 83  ? N VAL B 83  
AA7 1 2 N GLU B 114 ? N GLU B 114 O LEU B 123 ? O LEU B 123 
AA7 2 3 N ALA B 122 ? N ALA B 122 O ILE B 231 ? O ILE B 231 
AA7 3 4 O VAL B 225 ? O VAL B 225 N VAL B 183 ? N VAL B 183 
AA7 4 5 N VAL B 182 ? N VAL B 182 O VAL B 190 ? O VAL B 190 
AA8 1 2 O LYS B 346 ? O LYS B 346 N THR B 246 ? N THR B 246 
AA8 2 3 N ILE B 245 ? N ILE B 245 O PHE B 317 ? O PHE B 317 
AA8 3 4 O ASN B 316 ? O ASN B 316 N ARG B 276 ? N ARG B 276 
AA8 4 5 N SER B 277 ? N SER B 277 O GLY B 421 ? O GLY B 421 
AA8 5 6 N MET B 420 ? N MET B 420 O VAL B 435 ? O VAL B 435 
AA8 6 7 O THR B 434 ? O THR B 434 N PHE B 390 ? N PHE B 390 
AA9 1 2 O LYS B 346 ? O LYS B 346 N THR B 246 ? N THR B 246 
AA9 2 3 N ILE B 245 ? N ILE B 245 O PHE B 317 ? O PHE B 317 
AA9 3 4 O ASN B 316 ? O ASN B 316 N ARG B 276 ? N ARG B 276 
AA9 4 5 N SER B 277 ? N SER B 277 O GLY B 421 ? O GLY B 421 
AA9 5 6 N MET B 420 ? N MET B 420 O VAL B 435 ? O VAL B 435 
AA9 6 7 O LEU B 430 ? O LEU B 430 N SER B 394 ? N SER B 394 
AB1 1 2 N PHE C 31  ? N PHE C 31  O ALA C 57  ? O ALA C 57  
AB1 2 3 N ALA C 56  ? N ALA C 56  O VAL C 103 ? O VAL C 103 
AB1 3 4 O LEU C 104 ? O LEU C 104 N VAL C 83  ? N VAL C 83  
AB2 1 2 N GLU C 114 ? N GLU C 114 O LEU C 123 ? O LEU C 123 
AB2 2 3 N ALA C 122 ? N ALA C 122 O ILE C 231 ? O ILE C 231 
AB2 3 4 O GLY C 230 ? O GLY C 230 N GLY C 179 ? N GLY C 179 
AB2 4 5 N VAL C 182 ? N VAL C 182 O VAL C 190 ? O VAL C 190 
AB3 1 2 N TRP C 145 ? N TRP C 145 O MET C 234 ? O MET C 234 
AB4 1 2 O TYR C 348 ? O TYR C 348 N LEU C 244 ? N LEU C 244 
AB4 2 3 N ILE C 245 ? N ILE C 245 O PHE C 317 ? O PHE C 317 
AB4 3 4 O ASN C 316 ? O ASN C 316 N ARG C 276 ? N ARG C 276 
AB4 4 5 N SER C 277 ? N SER C 277 O GLY C 421 ? O GLY C 421 
AB4 5 6 N LEU C 422 ? N LEU C 422 O VAL C 433 ? O VAL C 433 
AB4 6 7 O ILE C 436 ? O ILE C 436 N VAL C 388 ? N VAL C 388 
# 
_pdbx_entry_details.entry_id                   8S7S 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NE2 C HIS 387 ? ? C8M C FAD 601 ? ? 1.49 
2 1 NE2 A HIS 387 ? ? C8M A FAD 601 ? ? 1.50 
3 1 NE2 B HIS 387 ? ? C8M B FAD 601 ? ? 1.51 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 5   ? ? -49.28  150.46  
2  1 GLU A 33  ? ? 58.67   -111.05 
3  1 LYS A 87  ? ? -96.40  42.27   
4  1 ALA A 90  ? ? 81.58   -4.45   
5  1 HIS A 163 ? ? 71.82   40.42   
6  1 GLN A 220 ? ? 37.25   54.03   
7  1 TYR A 240 ? ? -168.25 115.23  
8  1 PHE A 376 ? ? -59.84  3.84    
9  1 TRP A 427 ? ? -143.34 -64.52  
10 1 ALA A 507 ? ? 30.70   64.91   
11 1 SER A 511 ? ? 55.90   18.79   
12 1 THR B 32  ? ? -94.11  -154.33 
13 1 ASP B 34  ? ? 73.69   -42.79  
14 1 LYS B 87  ? ? -95.14  37.60   
15 1 ALA B 90  ? ? 88.46   -6.05   
16 1 GLU B 114 ? ? -173.39 133.51  
17 1 LYS B 143 ? ? -95.40  59.61   
18 1 TYR B 170 ? ? -94.10  31.10   
19 1 CYS B 178 ? ? -164.34 96.89   
20 1 GLN B 220 ? ? 37.00   62.11   
21 1 PHE B 376 ? ? -55.78  0.95    
22 1 TRP B 427 ? ? -128.77 -63.42  
23 1 TYR B 482 ? ? -97.52  57.95   
24 1 ASP B 501 ? ? -118.38 67.26   
25 1 ALA B 507 ? ? 33.89   61.87   
26 1 THR C 32  ? ? -128.98 -157.26 
27 1 GLU C 33  ? ? 54.05   -134.23 
28 1 ASP C 41  ? ? -40.56  108.38  
29 1 ARG C 85  ? ? -141.77 -16.21  
30 1 LYS C 87  ? ? -102.89 42.13   
31 1 ALA C 90  ? ? 86.30   -5.36   
32 1 VAL C 97  ? ? -27.59  -61.14  
33 1 TYR C 170 ? ? -89.59  31.71   
34 1 CYS C 178 ? ? -163.58 108.86  
35 1 GLN C 220 ? ? 34.61   57.96   
36 1 ASN C 271 ? ? -109.23 -168.86 
37 1 ASP C 311 ? ? 70.77   42.10   
38 1 PHE C 376 ? ? -57.54  2.51    
39 1 LEU C 422 ? ? -177.61 110.79  
40 1 TYR C 482 ? ? -102.90 65.24   
41 1 SER C 511 ? ? 54.52   17.23   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   GLY 
_pdbx_validate_peptide_omega.auth_asym_id_1   C 
_pdbx_validate_peptide_omega.auth_seq_id_1    515 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   LYS 
_pdbx_validate_peptide_omega.auth_asym_id_2   C 
_pdbx_validate_peptide_omega.auth_seq_id_2    516 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -148.83 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 241 ? ? 0.072 'SIDE CHAIN' 
2 1 ARG A 354 ? ? 0.098 'SIDE CHAIN' 
3 1 ARG A 411 ? ? 0.122 'SIDE CHAIN' 
4 1 ARG A 413 ? ? 0.082 'SIDE CHAIN' 
5 1 ARG B 353 ? ? 0.084 'SIDE CHAIN' 
6 1 ARG B 519 ? ? 0.086 'SIDE CHAIN' 
7 1 ARG C 191 ? ? 0.089 'SIDE CHAIN' 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A HOH 754 ? G HOH . 
2 1 A HOH 813 ? G HOH . 
3 1 B HOH 764 ? H HOH . 
4 1 C HOH 707 ? I HOH . 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 813 ? 6.86 . 
2 1 O ? C HOH 753 ? 6.70 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A MET 1   ? A MET 1   
2 1 Y 1 A LYS 520 ? A LYS 520 
3 1 Y 1 A ALA 521 ? A ALA 521 
4 1 Y 1 B MET 1   ? B MET 1   
5 1 Y 1 B LYS 520 ? B LYS 520 
6 1 Y 1 B ALA 521 ? B ALA 521 
7 1 Y 1 C MET 1   ? C MET 1   
8 1 Y 1 C LYS 520 ? C LYS 520 
9 1 Y 1 C ALA 521 ? C ALA 521 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
FAD PA     P N R 88  
FAD O1A    O N N 89  
FAD O2A    O N N 90  
FAD O5B    O N N 91  
FAD C5B    C N N 92  
FAD C4B    C N R 93  
FAD O4B    O N N 94  
FAD C3B    C N S 95  
FAD O3B    O N N 96  
FAD C2B    C N R 97  
FAD O2B    O N N 98  
FAD C1B    C N R 99  
FAD N9A    N Y N 100 
FAD C8A    C Y N 101 
FAD N7A    N Y N 102 
FAD C5A    C Y N 103 
FAD C6A    C Y N 104 
FAD N6A    N N N 105 
FAD N1A    N Y N 106 
FAD C2A    C Y N 107 
FAD N3A    N Y N 108 
FAD C4A    C Y N 109 
FAD N1     N N N 110 
FAD C2     C N N 111 
FAD O2     O N N 112 
FAD N3     N N N 113 
FAD C4     C N N 114 
FAD O4     O N N 115 
FAD C4X    C N N 116 
FAD N5     N N N 117 
FAD C5X    C Y N 118 
FAD C6     C Y N 119 
FAD C7     C Y N 120 
FAD C7M    C N N 121 
FAD C8     C Y N 122 
FAD C8M    C N N 123 
FAD C9     C Y N 124 
FAD C9A    C Y N 125 
FAD N10    N N N 126 
FAD C10    C N N 127 
FAD "C1'"  C N N 128 
FAD "C2'"  C N S 129 
FAD "O2'"  O N N 130 
FAD "C3'"  C N S 131 
FAD "O3'"  O N N 132 
FAD "C4'"  C N R 133 
FAD "O4'"  O N N 134 
FAD "C5'"  C N N 135 
FAD "O5'"  O N N 136 
FAD P      P N R 137 
FAD O1P    O N N 138 
FAD O2P    O N N 139 
FAD O3P    O N N 140 
FAD HOA2   H N N 141 
FAD H51A   H N N 142 
FAD H52A   H N N 143 
FAD H4B    H N N 144 
FAD H3B    H N N 145 
FAD HO3A   H N N 146 
FAD H2B    H N N 147 
FAD HO2A   H N N 148 
FAD H1B    H N N 149 
FAD H8A    H N N 150 
FAD H61A   H N N 151 
FAD H62A   H N N 152 
FAD H2A    H N N 153 
FAD HN3    H N N 154 
FAD H6     H N N 155 
FAD HM71   H N N 156 
FAD HM72   H N N 157 
FAD HM73   H N N 158 
FAD HM81   H N N 159 
FAD HM82   H N N 160 
FAD HM83   H N N 161 
FAD H9     H N N 162 
FAD "H1'1" H N N 163 
FAD "H1'2" H N N 164 
FAD "H2'"  H N N 165 
FAD "HO2'" H N N 166 
FAD "H3'"  H N N 167 
FAD "HO3'" H N N 168 
FAD "H4'"  H N N 169 
FAD "HO4'" H N N 170 
FAD "H5'1" H N N 171 
FAD "H5'2" H N N 172 
FAD HOP2   H N N 173 
GLN N      N N N 174 
GLN CA     C N S 175 
GLN C      C N N 176 
GLN O      O N N 177 
GLN CB     C N N 178 
GLN CG     C N N 179 
GLN CD     C N N 180 
GLN OE1    O N N 181 
GLN NE2    N N N 182 
GLN OXT    O N N 183 
GLN H      H N N 184 
GLN H2     H N N 185 
GLN HA     H N N 186 
GLN HB2    H N N 187 
GLN HB3    H N N 188 
GLN HG2    H N N 189 
GLN HG3    H N N 190 
GLN HE21   H N N 191 
GLN HE22   H N N 192 
GLN HXT    H N N 193 
GLU N      N N N 194 
GLU CA     C N S 195 
GLU C      C N N 196 
GLU O      O N N 197 
GLU CB     C N N 198 
GLU CG     C N N 199 
GLU CD     C N N 200 
GLU OE1    O N N 201 
GLU OE2    O N N 202 
GLU OXT    O N N 203 
GLU H      H N N 204 
GLU H2     H N N 205 
GLU HA     H N N 206 
GLU HB2    H N N 207 
GLU HB3    H N N 208 
GLU HG2    H N N 209 
GLU HG3    H N N 210 
GLU HE2    H N N 211 
GLU HXT    H N N 212 
GLY N      N N N 213 
GLY CA     C N N 214 
GLY C      C N N 215 
GLY O      O N N 216 
GLY OXT    O N N 217 
GLY H      H N N 218 
GLY H2     H N N 219 
GLY HA2    H N N 220 
GLY HA3    H N N 221 
GLY HXT    H N N 222 
HIS N      N N N 223 
HIS CA     C N S 224 
HIS C      C N N 225 
HIS O      O N N 226 
HIS CB     C N N 227 
HIS CG     C Y N 228 
HIS ND1    N Y N 229 
HIS CD2    C Y N 230 
HIS CE1    C Y N 231 
HIS NE2    N Y N 232 
HIS OXT    O N N 233 
HIS H      H N N 234 
HIS H2     H N N 235 
HIS HA     H N N 236 
HIS HB2    H N N 237 
HIS HB3    H N N 238 
HIS HD1    H N N 239 
HIS HD2    H N N 240 
HIS HE1    H N N 241 
HIS HE2    H N N 242 
HIS HXT    H N N 243 
HOH O      O N N 244 
HOH H1     H N N 245 
HOH H2     H N N 246 
ILE N      N N N 247 
ILE CA     C N S 248 
ILE C      C N N 249 
ILE O      O N N 250 
ILE CB     C N S 251 
ILE CG1    C N N 252 
ILE CG2    C N N 253 
ILE CD1    C N N 254 
ILE OXT    O N N 255 
ILE H      H N N 256 
ILE H2     H N N 257 
ILE HA     H N N 258 
ILE HB     H N N 259 
ILE HG12   H N N 260 
ILE HG13   H N N 261 
ILE HG21   H N N 262 
ILE HG22   H N N 263 
ILE HG23   H N N 264 
ILE HD11   H N N 265 
ILE HD12   H N N 266 
ILE HD13   H N N 267 
ILE HXT    H N N 268 
LEU N      N N N 269 
LEU CA     C N S 270 
LEU C      C N N 271 
LEU O      O N N 272 
LEU CB     C N N 273 
LEU CG     C N N 274 
LEU CD1    C N N 275 
LEU CD2    C N N 276 
LEU OXT    O N N 277 
LEU H      H N N 278 
LEU H2     H N N 279 
LEU HA     H N N 280 
LEU HB2    H N N 281 
LEU HB3    H N N 282 
LEU HG     H N N 283 
LEU HD11   H N N 284 
LEU HD12   H N N 285 
LEU HD13   H N N 286 
LEU HD21   H N N 287 
LEU HD22   H N N 288 
LEU HD23   H N N 289 
LEU HXT    H N N 290 
LYS N      N N N 291 
LYS CA     C N S 292 
LYS C      C N N 293 
LYS O      O N N 294 
LYS CB     C N N 295 
LYS CG     C N N 296 
LYS CD     C N N 297 
LYS CE     C N N 298 
LYS NZ     N N N 299 
LYS OXT    O N N 300 
LYS H      H N N 301 
LYS H2     H N N 302 
LYS HA     H N N 303 
LYS HB2    H N N 304 
LYS HB3    H N N 305 
LYS HG2    H N N 306 
LYS HG3    H N N 307 
LYS HD2    H N N 308 
LYS HD3    H N N 309 
LYS HE2    H N N 310 
LYS HE3    H N N 311 
LYS HZ1    H N N 312 
LYS HZ2    H N N 313 
LYS HZ3    H N N 314 
LYS HXT    H N N 315 
MET N      N N N 316 
MET CA     C N S 317 
MET C      C N N 318 
MET O      O N N 319 
MET CB     C N N 320 
MET CG     C N N 321 
MET SD     S N N 322 
MET CE     C N N 323 
MET OXT    O N N 324 
MET H      H N N 325 
MET H2     H N N 326 
MET HA     H N N 327 
MET HB2    H N N 328 
MET HB3    H N N 329 
MET HG2    H N N 330 
MET HG3    H N N 331 
MET HE1    H N N 332 
MET HE2    H N N 333 
MET HE3    H N N 334 
MET HXT    H N N 335 
PHE N      N N N 336 
PHE CA     C N S 337 
PHE C      C N N 338 
PHE O      O N N 339 
PHE CB     C N N 340 
PHE CG     C Y N 341 
PHE CD1    C Y N 342 
PHE CD2    C Y N 343 
PHE CE1    C Y N 344 
PHE CE2    C Y N 345 
PHE CZ     C Y N 346 
PHE OXT    O N N 347 
PHE H      H N N 348 
PHE H2     H N N 349 
PHE HA     H N N 350 
PHE HB2    H N N 351 
PHE HB3    H N N 352 
PHE HD1    H N N 353 
PHE HD2    H N N 354 
PHE HE1    H N N 355 
PHE HE2    H N N 356 
PHE HZ     H N N 357 
PHE HXT    H N N 358 
PRO N      N N N 359 
PRO CA     C N S 360 
PRO C      C N N 361 
PRO O      O N N 362 
PRO CB     C N N 363 
PRO CG     C N N 364 
PRO CD     C N N 365 
PRO OXT    O N N 366 
PRO H      H N N 367 
PRO HA     H N N 368 
PRO HB2    H N N 369 
PRO HB3    H N N 370 
PRO HG2    H N N 371 
PRO HG3    H N N 372 
PRO HD2    H N N 373 
PRO HD3    H N N 374 
PRO HXT    H N N 375 
SER N      N N N 376 
SER CA     C N S 377 
SER C      C N N 378 
SER O      O N N 379 
SER CB     C N N 380 
SER OG     O N N 381 
SER OXT    O N N 382 
SER H      H N N 383 
SER H2     H N N 384 
SER HA     H N N 385 
SER HB2    H N N 386 
SER HB3    H N N 387 
SER HG     H N N 388 
SER HXT    H N N 389 
THR N      N N N 390 
THR CA     C N S 391 
THR C      C N N 392 
THR O      O N N 393 
THR CB     C N R 394 
THR OG1    O N N 395 
THR CG2    C N N 396 
THR OXT    O N N 397 
THR H      H N N 398 
THR H2     H N N 399 
THR HA     H N N 400 
THR HB     H N N 401 
THR HG1    H N N 402 
THR HG21   H N N 403 
THR HG22   H N N 404 
THR HG23   H N N 405 
THR HXT    H N N 406 
TRP N      N N N 407 
TRP CA     C N S 408 
TRP C      C N N 409 
TRP O      O N N 410 
TRP CB     C N N 411 
TRP CG     C Y N 412 
TRP CD1    C Y N 413 
TRP CD2    C Y N 414 
TRP NE1    N Y N 415 
TRP CE2    C Y N 416 
TRP CE3    C Y N 417 
TRP CZ2    C Y N 418 
TRP CZ3    C Y N 419 
TRP CH2    C Y N 420 
TRP OXT    O N N 421 
TRP H      H N N 422 
TRP H2     H N N 423 
TRP HA     H N N 424 
TRP HB2    H N N 425 
TRP HB3    H N N 426 
TRP HD1    H N N 427 
TRP HE1    H N N 428 
TRP HE3    H N N 429 
TRP HZ2    H N N 430 
TRP HZ3    H N N 431 
TRP HH2    H N N 432 
TRP HXT    H N N 433 
TYR N      N N N 434 
TYR CA     C N S 435 
TYR C      C N N 436 
TYR O      O N N 437 
TYR CB     C N N 438 
TYR CG     C Y N 439 
TYR CD1    C Y N 440 
TYR CD2    C Y N 441 
TYR CE1    C Y N 442 
TYR CE2    C Y N 443 
TYR CZ     C Y N 444 
TYR OH     O N N 445 
TYR OXT    O N N 446 
TYR H      H N N 447 
TYR H2     H N N 448 
TYR HA     H N N 449 
TYR HB2    H N N 450 
TYR HB3    H N N 451 
TYR HD1    H N N 452 
TYR HD2    H N N 453 
TYR HE1    H N N 454 
TYR HE2    H N N 455 
TYR HH     H N N 456 
TYR HXT    H N N 457 
VAL N      N N N 458 
VAL CA     C N S 459 
VAL C      C N N 460 
VAL O      O N N 461 
VAL CB     C N N 462 
VAL CG1    C N N 463 
VAL CG2    C N N 464 
VAL OXT    O N N 465 
VAL H      H N N 466 
VAL H2     H N N 467 
VAL HA     H N N 468 
VAL HB     H N N 469 
VAL HG11   H N N 470 
VAL HG12   H N N 471 
VAL HG13   H N N 472 
VAL HG21   H N N 473 
VAL HG22   H N N 474 
VAL HG23   H N N 475 
VAL HXT    H N N 476 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
FAD PA    O1A    doub N N 83  
FAD PA    O2A    sing N N 84  
FAD PA    O5B    sing N N 85  
FAD PA    O3P    sing N N 86  
FAD O2A   HOA2   sing N N 87  
FAD O5B   C5B    sing N N 88  
FAD C5B   C4B    sing N N 89  
FAD C5B   H51A   sing N N 90  
FAD C5B   H52A   sing N N 91  
FAD C4B   O4B    sing N N 92  
FAD C4B   C3B    sing N N 93  
FAD C4B   H4B    sing N N 94  
FAD O4B   C1B    sing N N 95  
FAD C3B   O3B    sing N N 96  
FAD C3B   C2B    sing N N 97  
FAD C3B   H3B    sing N N 98  
FAD O3B   HO3A   sing N N 99  
FAD C2B   O2B    sing N N 100 
FAD C2B   C1B    sing N N 101 
FAD C2B   H2B    sing N N 102 
FAD O2B   HO2A   sing N N 103 
FAD C1B   N9A    sing N N 104 
FAD C1B   H1B    sing N N 105 
FAD N9A   C8A    sing Y N 106 
FAD N9A   C4A    sing Y N 107 
FAD C8A   N7A    doub Y N 108 
FAD C8A   H8A    sing N N 109 
FAD N7A   C5A    sing Y N 110 
FAD C5A   C6A    sing Y N 111 
FAD C5A   C4A    doub Y N 112 
FAD C6A   N6A    sing N N 113 
FAD C6A   N1A    doub Y N 114 
FAD N6A   H61A   sing N N 115 
FAD N6A   H62A   sing N N 116 
FAD N1A   C2A    sing Y N 117 
FAD C2A   N3A    doub Y N 118 
FAD C2A   H2A    sing N N 119 
FAD N3A   C4A    sing Y N 120 
FAD N1    C2     sing N N 121 
FAD N1    C10    doub N N 122 
FAD C2    O2     doub N N 123 
FAD C2    N3     sing N N 124 
FAD N3    C4     sing N N 125 
FAD N3    HN3    sing N N 126 
FAD C4    O4     doub N N 127 
FAD C4    C4X    sing N N 128 
FAD C4X   N5     doub N N 129 
FAD C4X   C10    sing N N 130 
FAD N5    C5X    sing N N 131 
FAD C5X   C6     doub Y N 132 
FAD C5X   C9A    sing Y N 133 
FAD C6    C7     sing Y N 134 
FAD C6    H6     sing N N 135 
FAD C7    C7M    sing N N 136 
FAD C7    C8     doub Y N 137 
FAD C7M   HM71   sing N N 138 
FAD C7M   HM72   sing N N 139 
FAD C7M   HM73   sing N N 140 
FAD C8    C8M    sing N N 141 
FAD C8    C9     sing Y N 142 
FAD C8M   HM81   sing N N 143 
FAD C8M   HM82   sing N N 144 
FAD C8M   HM83   sing N N 145 
FAD C9    C9A    doub Y N 146 
FAD C9    H9     sing N N 147 
FAD C9A   N10    sing N N 148 
FAD N10   C10    sing N N 149 
FAD N10   "C1'"  sing N N 150 
FAD "C1'" "C2'"  sing N N 151 
FAD "C1'" "H1'1" sing N N 152 
FAD "C1'" "H1'2" sing N N 153 
FAD "C2'" "O2'"  sing N N 154 
FAD "C2'" "C3'"  sing N N 155 
FAD "C2'" "H2'"  sing N N 156 
FAD "O2'" "HO2'" sing N N 157 
FAD "C3'" "O3'"  sing N N 158 
FAD "C3'" "C4'"  sing N N 159 
FAD "C3'" "H3'"  sing N N 160 
FAD "O3'" "HO3'" sing N N 161 
FAD "C4'" "O4'"  sing N N 162 
FAD "C4'" "C5'"  sing N N 163 
FAD "C4'" "H4'"  sing N N 164 
FAD "O4'" "HO4'" sing N N 165 
FAD "C5'" "O5'"  sing N N 166 
FAD "C5'" "H5'1" sing N N 167 
FAD "C5'" "H5'2" sing N N 168 
FAD "O5'" P      sing N N 169 
FAD P     O1P    doub N N 170 
FAD P     O2P    sing N N 171 
FAD P     O3P    sing N N 172 
FAD O2P   HOP2   sing N N 173 
GLN N     CA     sing N N 174 
GLN N     H      sing N N 175 
GLN N     H2     sing N N 176 
GLN CA    C      sing N N 177 
GLN CA    CB     sing N N 178 
GLN CA    HA     sing N N 179 
GLN C     O      doub N N 180 
GLN C     OXT    sing N N 181 
GLN CB    CG     sing N N 182 
GLN CB    HB2    sing N N 183 
GLN CB    HB3    sing N N 184 
GLN CG    CD     sing N N 185 
GLN CG    HG2    sing N N 186 
GLN CG    HG3    sing N N 187 
GLN CD    OE1    doub N N 188 
GLN CD    NE2    sing N N 189 
GLN NE2   HE21   sing N N 190 
GLN NE2   HE22   sing N N 191 
GLN OXT   HXT    sing N N 192 
GLU N     CA     sing N N 193 
GLU N     H      sing N N 194 
GLU N     H2     sing N N 195 
GLU CA    C      sing N N 196 
GLU CA    CB     sing N N 197 
GLU CA    HA     sing N N 198 
GLU C     O      doub N N 199 
GLU C     OXT    sing N N 200 
GLU CB    CG     sing N N 201 
GLU CB    HB2    sing N N 202 
GLU CB    HB3    sing N N 203 
GLU CG    CD     sing N N 204 
GLU CG    HG2    sing N N 205 
GLU CG    HG3    sing N N 206 
GLU CD    OE1    doub N N 207 
GLU CD    OE2    sing N N 208 
GLU OE2   HE2    sing N N 209 
GLU OXT   HXT    sing N N 210 
GLY N     CA     sing N N 211 
GLY N     H      sing N N 212 
GLY N     H2     sing N N 213 
GLY CA    C      sing N N 214 
GLY CA    HA2    sing N N 215 
GLY CA    HA3    sing N N 216 
GLY C     O      doub N N 217 
GLY C     OXT    sing N N 218 
GLY OXT   HXT    sing N N 219 
HIS N     CA     sing N N 220 
HIS N     H      sing N N 221 
HIS N     H2     sing N N 222 
HIS CA    C      sing N N 223 
HIS CA    CB     sing N N 224 
HIS CA    HA     sing N N 225 
HIS C     O      doub N N 226 
HIS C     OXT    sing N N 227 
HIS CB    CG     sing N N 228 
HIS CB    HB2    sing N N 229 
HIS CB    HB3    sing N N 230 
HIS CG    ND1    sing Y N 231 
HIS CG    CD2    doub Y N 232 
HIS ND1   CE1    doub Y N 233 
HIS ND1   HD1    sing N N 234 
HIS CD2   NE2    sing Y N 235 
HIS CD2   HD2    sing N N 236 
HIS CE1   NE2    sing Y N 237 
HIS CE1   HE1    sing N N 238 
HIS NE2   HE2    sing N N 239 
HIS OXT   HXT    sing N N 240 
HOH O     H1     sing N N 241 
HOH O     H2     sing N N 242 
ILE N     CA     sing N N 243 
ILE N     H      sing N N 244 
ILE N     H2     sing N N 245 
ILE CA    C      sing N N 246 
ILE CA    CB     sing N N 247 
ILE CA    HA     sing N N 248 
ILE C     O      doub N N 249 
ILE C     OXT    sing N N 250 
ILE CB    CG1    sing N N 251 
ILE CB    CG2    sing N N 252 
ILE CB    HB     sing N N 253 
ILE CG1   CD1    sing N N 254 
ILE CG1   HG12   sing N N 255 
ILE CG1   HG13   sing N N 256 
ILE CG2   HG21   sing N N 257 
ILE CG2   HG22   sing N N 258 
ILE CG2   HG23   sing N N 259 
ILE CD1   HD11   sing N N 260 
ILE CD1   HD12   sing N N 261 
ILE CD1   HD13   sing N N 262 
ILE OXT   HXT    sing N N 263 
LEU N     CA     sing N N 264 
LEU N     H      sing N N 265 
LEU N     H2     sing N N 266 
LEU CA    C      sing N N 267 
LEU CA    CB     sing N N 268 
LEU CA    HA     sing N N 269 
LEU C     O      doub N N 270 
LEU C     OXT    sing N N 271 
LEU CB    CG     sing N N 272 
LEU CB    HB2    sing N N 273 
LEU CB    HB3    sing N N 274 
LEU CG    CD1    sing N N 275 
LEU CG    CD2    sing N N 276 
LEU CG    HG     sing N N 277 
LEU CD1   HD11   sing N N 278 
LEU CD1   HD12   sing N N 279 
LEU CD1   HD13   sing N N 280 
LEU CD2   HD21   sing N N 281 
LEU CD2   HD22   sing N N 282 
LEU CD2   HD23   sing N N 283 
LEU OXT   HXT    sing N N 284 
LYS N     CA     sing N N 285 
LYS N     H      sing N N 286 
LYS N     H2     sing N N 287 
LYS CA    C      sing N N 288 
LYS CA    CB     sing N N 289 
LYS CA    HA     sing N N 290 
LYS C     O      doub N N 291 
LYS C     OXT    sing N N 292 
LYS CB    CG     sing N N 293 
LYS CB    HB2    sing N N 294 
LYS CB    HB3    sing N N 295 
LYS CG    CD     sing N N 296 
LYS CG    HG2    sing N N 297 
LYS CG    HG3    sing N N 298 
LYS CD    CE     sing N N 299 
LYS CD    HD2    sing N N 300 
LYS CD    HD3    sing N N 301 
LYS CE    NZ     sing N N 302 
LYS CE    HE2    sing N N 303 
LYS CE    HE3    sing N N 304 
LYS NZ    HZ1    sing N N 305 
LYS NZ    HZ2    sing N N 306 
LYS NZ    HZ3    sing N N 307 
LYS OXT   HXT    sing N N 308 
MET N     CA     sing N N 309 
MET N     H      sing N N 310 
MET N     H2     sing N N 311 
MET CA    C      sing N N 312 
MET CA    CB     sing N N 313 
MET CA    HA     sing N N 314 
MET C     O      doub N N 315 
MET C     OXT    sing N N 316 
MET CB    CG     sing N N 317 
MET CB    HB2    sing N N 318 
MET CB    HB3    sing N N 319 
MET CG    SD     sing N N 320 
MET CG    HG2    sing N N 321 
MET CG    HG3    sing N N 322 
MET SD    CE     sing N N 323 
MET CE    HE1    sing N N 324 
MET CE    HE2    sing N N 325 
MET CE    HE3    sing N N 326 
MET OXT   HXT    sing N N 327 
PHE N     CA     sing N N 328 
PHE N     H      sing N N 329 
PHE N     H2     sing N N 330 
PHE CA    C      sing N N 331 
PHE CA    CB     sing N N 332 
PHE CA    HA     sing N N 333 
PHE C     O      doub N N 334 
PHE C     OXT    sing N N 335 
PHE CB    CG     sing N N 336 
PHE CB    HB2    sing N N 337 
PHE CB    HB3    sing N N 338 
PHE CG    CD1    doub Y N 339 
PHE CG    CD2    sing Y N 340 
PHE CD1   CE1    sing Y N 341 
PHE CD1   HD1    sing N N 342 
PHE CD2   CE2    doub Y N 343 
PHE CD2   HD2    sing N N 344 
PHE CE1   CZ     doub Y N 345 
PHE CE1   HE1    sing N N 346 
PHE CE2   CZ     sing Y N 347 
PHE CE2   HE2    sing N N 348 
PHE CZ    HZ     sing N N 349 
PHE OXT   HXT    sing N N 350 
PRO N     CA     sing N N 351 
PRO N     CD     sing N N 352 
PRO N     H      sing N N 353 
PRO CA    C      sing N N 354 
PRO CA    CB     sing N N 355 
PRO CA    HA     sing N N 356 
PRO C     O      doub N N 357 
PRO C     OXT    sing N N 358 
PRO CB    CG     sing N N 359 
PRO CB    HB2    sing N N 360 
PRO CB    HB3    sing N N 361 
PRO CG    CD     sing N N 362 
PRO CG    HG2    sing N N 363 
PRO CG    HG3    sing N N 364 
PRO CD    HD2    sing N N 365 
PRO CD    HD3    sing N N 366 
PRO OXT   HXT    sing N N 367 
SER N     CA     sing N N 368 
SER N     H      sing N N 369 
SER N     H2     sing N N 370 
SER CA    C      sing N N 371 
SER CA    CB     sing N N 372 
SER CA    HA     sing N N 373 
SER C     O      doub N N 374 
SER C     OXT    sing N N 375 
SER CB    OG     sing N N 376 
SER CB    HB2    sing N N 377 
SER CB    HB3    sing N N 378 
SER OG    HG     sing N N 379 
SER OXT   HXT    sing N N 380 
THR N     CA     sing N N 381 
THR N     H      sing N N 382 
THR N     H2     sing N N 383 
THR CA    C      sing N N 384 
THR CA    CB     sing N N 385 
THR CA    HA     sing N N 386 
THR C     O      doub N N 387 
THR C     OXT    sing N N 388 
THR CB    OG1    sing N N 389 
THR CB    CG2    sing N N 390 
THR CB    HB     sing N N 391 
THR OG1   HG1    sing N N 392 
THR CG2   HG21   sing N N 393 
THR CG2   HG22   sing N N 394 
THR CG2   HG23   sing N N 395 
THR OXT   HXT    sing N N 396 
TRP N     CA     sing N N 397 
TRP N     H      sing N N 398 
TRP N     H2     sing N N 399 
TRP CA    C      sing N N 400 
TRP CA    CB     sing N N 401 
TRP CA    HA     sing N N 402 
TRP C     O      doub N N 403 
TRP C     OXT    sing N N 404 
TRP CB    CG     sing N N 405 
TRP CB    HB2    sing N N 406 
TRP CB    HB3    sing N N 407 
TRP CG    CD1    doub Y N 408 
TRP CG    CD2    sing Y N 409 
TRP CD1   NE1    sing Y N 410 
TRP CD1   HD1    sing N N 411 
TRP CD2   CE2    doub Y N 412 
TRP CD2   CE3    sing Y N 413 
TRP NE1   CE2    sing Y N 414 
TRP NE1   HE1    sing N N 415 
TRP CE2   CZ2    sing Y N 416 
TRP CE3   CZ3    doub Y N 417 
TRP CE3   HE3    sing N N 418 
TRP CZ2   CH2    doub Y N 419 
TRP CZ2   HZ2    sing N N 420 
TRP CZ3   CH2    sing Y N 421 
TRP CZ3   HZ3    sing N N 422 
TRP CH2   HH2    sing N N 423 
TRP OXT   HXT    sing N N 424 
TYR N     CA     sing N N 425 
TYR N     H      sing N N 426 
TYR N     H2     sing N N 427 
TYR CA    C      sing N N 428 
TYR CA    CB     sing N N 429 
TYR CA    HA     sing N N 430 
TYR C     O      doub N N 431 
TYR C     OXT    sing N N 432 
TYR CB    CG     sing N N 433 
TYR CB    HB2    sing N N 434 
TYR CB    HB3    sing N N 435 
TYR CG    CD1    doub Y N 436 
TYR CG    CD2    sing Y N 437 
TYR CD1   CE1    sing Y N 438 
TYR CD1   HD1    sing N N 439 
TYR CD2   CE2    doub Y N 440 
TYR CD2   HD2    sing N N 441 
TYR CE1   CZ     doub Y N 442 
TYR CE1   HE1    sing N N 443 
TYR CE2   CZ     sing Y N 444 
TYR CE2   HE2    sing N N 445 
TYR CZ    OH     sing N N 446 
TYR OH    HH     sing N N 447 
TYR OXT   HXT    sing N N 448 
VAL N     CA     sing N N 449 
VAL N     H      sing N N 450 
VAL N     H2     sing N N 451 
VAL CA    C      sing N N 452 
VAL CA    CB     sing N N 453 
VAL CA    HA     sing N N 454 
VAL C     O      doub N N 455 
VAL C     OXT    sing N N 456 
VAL CB    CG1    sing N N 457 
VAL CB    CG2    sing N N 458 
VAL CB    HB     sing N N 459 
VAL CG1   HG11   sing N N 460 
VAL CG1   HG12   sing N N 461 
VAL CG1   HG13   sing N N 462 
VAL CG2   HG21   sing N N 463 
VAL CG2   HG22   sing N N 464 
VAL CG2   HG23   sing N N 465 
VAL OXT   HXT    sing N N 466 
# 
_pdbx_audit_support.funding_organization   'European Commission' 
_pdbx_audit_support.country                'European Union' 
_pdbx_audit_support.grant_number           'B-Ligzymes (GA 824017)' 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8S7S 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011013 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006937 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.003455 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N     . ALA A 1 2   ? -14.831 -31.565 -20.142  1.00 97.46  ? 2   ALA A N     1 
ATOM   2     C CA    . ALA A 1 2   ? -14.824 -31.175 -18.709  1.00 99.24  ? 2   ALA A CA    1 
ATOM   3     C C     . ALA A 1 2   ? -14.837 -29.647 -18.610  1.00 103.64 ? 2   ALA A C     1 
ATOM   4     O O     . ALA A 1 2   ? -14.913 -28.967 -19.637  1.00 83.72  ? 2   ALA A O     1 
ATOM   5     C CB    . ALA A 1 2   ? -13.630 -31.795 -18.006  1.00 90.04  ? 2   ALA A CB    1 
ATOM   6     N N     . ALA A 1 3   ? -14.787 -29.134 -17.365  1.00 120.07 ? 3   ALA A N     1 
ATOM   7     C CA    . ALA A 1 3   ? -14.678 -27.708 -17.061  1.00 100.85 ? 3   ALA A CA    1 
ATOM   8     C C     . ALA A 1 3   ? -13.232 -27.355 -16.708  1.00 75.28  ? 3   ALA A C     1 
ATOM   9     O O     . ALA A 1 3   ? -12.548 -28.105 -16.000  1.00 75.50  ? 3   ALA A O     1 
ATOM   10    C CB    . ALA A 1 3   ? -15.613 -27.327 -15.926  1.00 100.49 ? 3   ALA A CB    1 
ATOM   11    N N     . PRO A 1 4   ? -12.722 -26.200 -17.185  1.00 71.44  ? 4   PRO A N     1 
ATOM   12    C CA    . PRO A 1 4   ? -11.348 -25.786 -16.887  1.00 83.60  ? 4   PRO A CA    1 
ATOM   13    C C     . PRO A 1 4   ? -11.201 -25.074 -15.540  1.00 80.93  ? 4   PRO A C     1 
ATOM   14    O O     . PRO A 1 4   ? -12.158 -24.490 -15.042  1.00 98.32  ? 4   PRO A O     1 
ATOM   15    C CB    . PRO A 1 4   ? -11.019 -24.828 -18.053  1.00 90.87  ? 4   PRO A CB    1 
ATOM   16    C CG    . PRO A 1 4   ? -12.363 -24.231 -18.474  1.00 88.13  ? 4   PRO A CG    1 
ATOM   17    C CD    . PRO A 1 4   ? -13.420 -25.247 -18.069  1.00 84.06  ? 4   PRO A CD    1 
ATOM   18    N N     . LEU A 1 5   ? -9.998  -25.138 -14.960  1.00 72.78  ? 5   LEU A N     1 
ATOM   19    C CA    . LEU A 1 5   ? -9.606  -24.306 -13.837  1.00 69.19  ? 5   LEU A CA    1 
ATOM   20    C C     . LEU A 1 5   ? -9.936  -22.840 -14.131  1.00 83.18  ? 5   LEU A C     1 
ATOM   21    O O     . LEU A 1 5   ? -9.950  -22.427 -15.288  1.00 81.91  ? 5   LEU A O     1 
ATOM   22    C CB    . LEU A 1 5   ? -8.099  -24.455 -13.622  1.00 78.18  ? 5   LEU A CB    1 
ATOM   23    C CG    . LEU A 1 5   ? -7.574  -25.863 -13.340  1.00 82.51  ? 5   LEU A CG    1 
ATOM   24    C CD1   . LEU A 1 5   ? -6.086  -25.823 -13.007  1.00 80.62  ? 5   LEU A CD1   1 
ATOM   25    C CD2   . LEU A 1 5   ? -8.355  -26.527 -12.215  1.00 85.83  ? 5   LEU A CD2   1 
ATOM   26    N N     . PRO A 1 6   ? -10.232 -21.998 -13.109  1.00 96.99  ? 6   PRO A N     1 
ATOM   27    C CA    . PRO A 1 6   ? -10.467 -20.569 -13.340  1.00 86.96  ? 6   PRO A CA    1 
ATOM   28    C C     . PRO A 1 6   ? -9.122  -19.861 -13.506  1.00 86.08  ? 6   PRO A C     1 
ATOM   29    O O     . PRO A 1 6   ? -8.154  -20.231 -12.840  1.00 85.65  ? 6   PRO A O     1 
ATOM   30    C CB    . PRO A 1 6   ? -11.231 -20.128 -12.089  1.00 83.36  ? 6   PRO A CB    1 
ATOM   31    C CG    . PRO A 1 6   ? -10.773 -21.097 -10.990  1.00 85.97  ? 6   PRO A CG    1 
ATOM   32    C CD    . PRO A 1 6   ? -10.355 -22.376 -11.687  1.00 91.39  ? 6   PRO A CD    1 
ATOM   33    N N     . GLU A 1 7   ? -9.052  -18.875 -14.415  1.00 83.36  ? 7   GLU A N     1 
ATOM   34    C CA    . GLU A 1 7   ? -7.765  -18.322 -14.806  1.00 84.08  ? 7   GLU A CA    1 
ATOM   35    C C     . GLU A 1 7   ? -7.063  -17.754 -13.573  1.00 77.89  ? 7   GLU A C     1 
ATOM   36    O O     . GLU A 1 7   ? -7.672  -17.046 -12.784  1.00 79.36  ? 7   GLU A O     1 
ATOM   37    C CB    . GLU A 1 7   ? -7.895  -17.244 -15.882  1.00 88.88  ? 7   GLU A CB    1 
ATOM   38    C CG    . GLU A 1 7   ? -6.541  -16.681 -16.305  1.00 98.47  ? 7   GLU A CG    1 
ATOM   39    C CD    . GLU A 1 7   ? -6.560  -15.656 -17.429  1.00 107.25 ? 7   GLU A CD    1 
ATOM   40    O OE1   . GLU A 1 7   ? -7.667  -15.335 -17.929  1.00 108.23 ? 7   GLU A OE1   1 
ATOM   41    O OE2   . GLU A 1 7   ? -5.464  -15.176 -17.805  1.00 98.93  ? 7   GLU A OE2   1 
ATOM   42    N N     . GLY A 1 8   ? -5.783  -18.095 -13.408  1.00 74.38  ? 8   GLY A N     1 
ATOM   43    C CA    . GLY A 1 8   ? -4.972  -17.563 -12.328  1.00 67.27  ? 8   GLY A CA    1 
ATOM   44    C C     . GLY A 1 8   ? -4.892  -18.497 -11.123  1.00 66.07  ? 8   GLY A C     1 
ATOM   45    O O     . GLY A 1 8   ? -4.322  -18.108 -10.111  1.00 66.52  ? 8   GLY A O     1 
ATOM   46    N N     . VAL A 1 9   ? -5.426  -19.724 -11.238  1.00 65.91  ? 9   VAL A N     1 
ATOM   47    C CA    . VAL A 1 9   ? -5.588  -20.602 -10.084  1.00 72.52  ? 9   VAL A CA    1 
ATOM   48    C C     . VAL A 1 9   ? -4.897  -21.927 -10.361  1.00 79.25  ? 9   VAL A C     1 
ATOM   49    O O     . VAL A 1 9   ? -5.383  -22.700 -11.179  1.00 76.17  ? 9   VAL A O     1 
ATOM   50    C CB    . VAL A 1 9   ? -7.076  -20.850 -9.759   1.00 82.06  ? 9   VAL A CB    1 
ATOM   51    C CG1   . VAL A 1 9   ? -7.265  -21.821 -8.595   1.00 76.48  ? 9   VAL A CG1   1 
ATOM   52    C CG2   . VAL A 1 9   ? -7.813  -19.542 -9.490   1.00 81.63  ? 9   VAL A CG2   1 
ATOM   53    N N     . SER A 1 10  ? -3.805  -22.207 -9.637   1.00 86.22  ? 10  SER A N     1 
ATOM   54    C CA    . SER A 1 10  ? -3.046  -23.427 -9.865   1.00 80.27  ? 10  SER A CA    1 
ATOM   55    C C     . SER A 1 10  ? -3.909  -24.653 -9.535   1.00 83.38  ? 10  SER A C     1 
ATOM   56    O O     . SER A 1 10  ? -4.810  -24.574 -8.707   1.00 78.34  ? 10  SER A O     1 
ATOM   57    C CB    . SER A 1 10  ? -1.746  -23.414 -9.088   1.00 75.29  ? 10  SER A CB    1 
ATOM   58    O OG    . SER A 1 10  ? -1.901  -23.983 -7.799   1.00 80.94  ? 10  SER A OG    1 
ATOM   59    N N     . ALA A 1 11  ? -3.626  -25.782 -10.198  1.00 83.94  ? 11  ALA A N     1 
ATOM   60    C CA    . ALA A 1 11  ? -4.330  -27.035 -9.967   1.00 83.65  ? 11  ALA A CA    1 
ATOM   61    C C     . ALA A 1 11  ? -4.029  -27.578 -8.567   1.00 77.34  ? 11  ALA A C     1 
ATOM   62    O O     . ALA A 1 11  ? -4.850  -28.300 -8.005   1.00 74.61  ? 11  ALA A O     1 
ATOM   63    C CB    . ALA A 1 11  ? -3.969  -28.046 -11.040  1.00 78.90  ? 11  ALA A CB    1 
ATOM   64    N N     . GLU A 1 12  ? -2.861  -27.247 -8.002   1.00 79.78  ? 12  GLU A N     1 
ATOM   65    C CA    . GLU A 1 12  ? -2.540  -27.686 -6.647   1.00 101.65 ? 12  GLU A CA    1 
ATOM   66    C C     . GLU A 1 12  ? -3.444  -26.951 -5.660   1.00 107.66 ? 12  GLU A C     1 
ATOM   67    O O     . GLU A 1 12  ? -4.054  -27.574 -4.791   1.00 113.98 ? 12  GLU A O     1 
ATOM   68    C CB    . GLU A 1 12  ? -1.089  -27.401 -6.239   1.00 106.24 ? 12  GLU A CB    1 
ATOM   69    C CG    . GLU A 1 12  ? -0.047  -28.184 -7.015   1.00 108.26 ? 12  GLU A CG    1 
ATOM   70    C CD    . GLU A 1 12  ? 0.244   -27.624 -8.396   1.00 107.09 ? 12  GLU A CD    1 
ATOM   71    O OE1   . GLU A 1 12  ? 0.162   -28.400 -9.374   1.00 95.88  ? 12  GLU A OE1   1 
ATOM   72    O OE2   . GLU A 1 12  ? 0.527   -26.403 -8.489   1.00 101.66 ? 12  GLU A OE2   1 
ATOM   73    N N     . ALA A 1 13  ? -3.507  -25.619 -5.825   1.00 101.72 ? 13  ALA A N     1 
ATOM   74    C CA    . ALA A 1 13  ? -4.225  -24.724 -4.931   1.00 81.04  ? 13  ALA A CA    1 
ATOM   75    C C     . ALA A 1 13  ? -5.714  -25.067 -4.912   1.00 77.38  ? 13  ALA A C     1 
ATOM   76    O O     . ALA A 1 13  ? -6.363  -24.943 -3.873   1.00 74.24  ? 13  ALA A O     1 
ATOM   77    C CB    . ALA A 1 13  ? -3.984  -23.290 -5.345   1.00 75.06  ? 13  ALA A CB    1 
ATOM   78    N N     . MET A 1 14  ? -6.238  -25.513 -6.061   1.00 75.29  ? 14  MET A N     1 
ATOM   79    C CA    . MET A 1 14  ? -7.638  -25.878 -6.184   1.00 72.57  ? 14  MET A CA    1 
ATOM   80    C C     . MET A 1 14  ? -7.913  -27.168 -5.427   1.00 76.51  ? 14  MET A C     1 
ATOM   81    O O     . MET A 1 14  ? -8.976  -27.297 -4.829   1.00 92.48  ? 14  MET A O     1 
ATOM   82    C CB    . MET A 1 14  ? -8.067  -26.071 -7.639   1.00 64.80  ? 14  MET A CB    1 
ATOM   83    C CG    . MET A 1 14  ? -9.490  -26.590 -7.787   1.00 77.21  ? 14  MET A CG    1 
ATOM   84    S SD    . MET A 1 14  ? -10.776 -25.411 -7.220   1.00 76.80  ? 14  MET A SD    1 
ATOM   85    C CE    . MET A 1 14  ? -11.248 -24.661 -8.780   1.00 82.71  ? 14  MET A CE    1 
ATOM   86    N N     . SER A 1 15  ? -6.987  -28.127 -5.478   1.00 87.95  ? 15  SER A N     1 
ATOM   87    C CA    . SER A 1 15  ? -7.225  -29.409 -4.826   1.00 92.09  ? 15  SER A CA    1 
ATOM   88    C C     . SER A 1 15  ? -6.946  -29.293 -3.321   1.00 73.58  ? 15  SER A C     1 
ATOM   89    O O     . SER A 1 15  ? -7.509  -30.050 -2.538   1.00 75.93  ? 15  SER A O     1 
ATOM   90    C CB    . SER A 1 15  ? -6.450  -30.530 -5.491   1.00 87.03  ? 15  SER A CB    1 
ATOM   91    O OG    . SER A 1 15  ? -5.098  -30.512 -5.067   1.00 90.22  ? 15  SER A OG    1 
ATOM   92    N N     . SER A 1 16  ? -6.092  -28.345 -2.913   1.00 63.41  ? 16  SER A N     1 
ATOM   93    C CA    . SER A 1 16  ? -5.927  -28.003 -1.503   1.00 75.61  ? 16  SER A CA    1 
ATOM   94    C C     . SER A 1 16  ? -7.221  -27.408 -0.932   1.00 85.01  ? 16  SER A C     1 
ATOM   95    O O     . SER A 1 16  ? -7.626  -27.714 0.189    1.00 95.82  ? 16  SER A O     1 
ATOM   96    C CB    . SER A 1 16  ? -4.792  -27.021 -1.301   1.00 79.45  ? 16  SER A CB    1 
ATOM   97    O OG    . SER A 1 16  ? -3.630  -27.406 -2.016   1.00 84.24  ? 16  SER A OG    1 
ATOM   98    N N     . ALA A 1 17  ? -7.832  -26.510 -1.711   1.00 73.43  ? 17  ALA A N     1 
ATOM   99    C CA    . ALA A 1 17  ? -9.090  -25.881 -1.373   1.00 65.35  ? 17  ALA A CA    1 
ATOM   100   C C     . ALA A 1 17  ? -10.191 -26.926 -1.236   1.00 68.21  ? 17  ALA A C     1 
ATOM   101   O O     . ALA A 1 17  ? -10.953 -26.883 -0.270   1.00 76.02  ? 17  ALA A O     1 
ATOM   102   C CB    . ALA A 1 17  ? -9.437  -24.853 -2.425   1.00 69.62  ? 17  ALA A CB    1 
ATOM   103   N N     . LEU A 1 18  ? -10.280 -27.860 -2.191   1.00 58.79  ? 18  LEU A N     1 
ATOM   104   C CA    . LEU A 1 18  ? -11.360 -28.828 -2.172   1.00 58.24  ? 18  LEU A CA    1 
ATOM   105   C C     . LEU A 1 18  ? -11.222 -29.728 -0.948   1.00 62.85  ? 18  LEU A C     1 
ATOM   106   O O     . LEU A 1 18  ? -12.217 -30.193 -0.399   1.00 67.53  ? 18  LEU A O     1 
ATOM   107   C CB    . LEU A 1 18  ? -11.374 -29.644 -3.469   1.00 71.59  ? 18  LEU A CB    1 
ATOM   108   C CG    . LEU A 1 18  ? -11.760 -28.886 -4.745   1.00 86.22  ? 18  LEU A CG    1 
ATOM   109   C CD1   . LEU A 1 18  ? -12.040 -29.854 -5.886   1.00 93.50  ? 18  LEU A CD1   1 
ATOM   110   C CD2   . LEU A 1 18  ? -12.963 -27.975 -4.531   1.00 86.21  ? 18  LEU A CD2   1 
ATOM   111   N N     . ASP A 1 19  ? -9.991  -29.966 -0.500   1.00 69.40  ? 19  ASP A N     1 
ATOM   112   C CA    . ASP A 1 19  ? -9.782  -30.847 0.634    1.00 79.18  ? 19  ASP A CA    1 
ATOM   113   C C     . ASP A 1 19  ? -10.197 -30.109 1.902    1.00 76.40  ? 19  ASP A C     1 
ATOM   114   O O     . ASP A 1 19  ? -10.894 -30.681 2.738    1.00 68.51  ? 19  ASP A O     1 
ATOM   115   C CB    . ASP A 1 19  ? -8.346  -31.377 0.671    1.00 89.10  ? 19  ASP A CB    1 
ATOM   116   C CG    . ASP A 1 19  ? -8.064  -32.413 -0.407   1.00 100.52 ? 19  ASP A CG    1 
ATOM   117   O OD1   . ASP A 1 19  ? -9.008  -32.758 -1.169   1.00 100.48 ? 19  ASP A OD1   1 
ATOM   118   O OD2   . ASP A 1 19  ? -6.905  -32.874 -0.479   1.00 116.43 ? 19  ASP A OD2   1 
ATOM   119   N N     . ARG A 1 20  ? -9.820  -28.824 2.015    1.00 68.33  ? 20  ARG A N     1 
ATOM   120   C CA    . ARG A 1 20  ? -10.120 -28.080 3.227    1.00 62.12  ? 20  ARG A CA    1 
ATOM   121   C C     . ARG A 1 20  ? -11.619 -27.736 3.277    1.00 62.22  ? 20  ARG A C     1 
ATOM   122   O O     . ARG A 1 20  ? -12.184 -27.657 4.369    1.00 56.52  ? 20  ARG A O     1 
ATOM   123   C CB    . ARG A 1 20  ? -9.149  -26.912 3.391    1.00 55.83  ? 20  ARG A CB    1 
ATOM   124   C CG    . ARG A 1 20  ? -8.785  -26.642 4.848    1.00 70.74  ? 20  ARG A CG    1 
ATOM   125   C CD    . ARG A 1 20  ? -7.591  -25.716 5.066    1.00 74.68  ? 20  ARG A CD    1 
ATOM   126   N NE    . ARG A 1 20  ? -6.374  -26.279 4.496    1.00 83.99  ? 20  ARG A NE    1 
ATOM   127   C CZ    . ARG A 1 20  ? -5.174  -25.692 4.489    1.00 100.49 ? 20  ARG A CZ    1 
ATOM   128   N NH1   . ARG A 1 20  ? -5.004  -24.488 5.016    1.00 101.41 ? 20  ARG A NH1   1 
ATOM   129   N NH2   . ARG A 1 20  ? -4.139  -26.324 3.951    1.00 88.83  ? 20  ARG A NH2   1 
ATOM   130   N N     . PHE A 1 21  ? -12.285 -27.612 2.115    1.00 54.80  ? 21  PHE A N     1 
ATOM   131   C CA    . PHE A 1 21  ? -13.742 -27.537 2.080    1.00 56.79  ? 21  PHE A CA    1 
ATOM   132   C C     . PHE A 1 21  ? -14.358 -28.829 2.607    1.00 63.84  ? 21  PHE A C     1 
ATOM   133   O O     . PHE A 1 21  ? -15.447 -28.811 3.163    1.00 68.77  ? 21  PHE A O     1 
ATOM   134   C CB    . PHE A 1 21  ? -14.303 -27.379 0.658    1.00 60.49  ? 21  PHE A CB    1 
ATOM   135   C CG    . PHE A 1 21  ? -14.030 -26.084 -0.083   1.00 60.91  ? 21  PHE A CG    1 
ATOM   136   C CD1   . PHE A 1 21  ? -13.729 -24.900 0.578    1.00 52.87  ? 21  PHE A CD1   1 
ATOM   137   C CD2   . PHE A 1 21  ? -14.088 -26.051 -1.468   1.00 57.56  ? 21  PHE A CD2   1 
ATOM   138   C CE1   . PHE A 1 21  ? -13.477 -23.738 -0.127   1.00 49.71  ? 21  PHE A CE1   1 
ATOM   139   C CE2   . PHE A 1 21  ? -13.828 -24.885 -2.170   1.00 57.24  ? 21  PHE A CE2   1 
ATOM   140   C CZ    . PHE A 1 21  ? -13.518 -23.734 -1.499   1.00 52.63  ? 21  PHE A CZ    1 
ATOM   141   N N     . ALA A 1 22  ? -13.698 -29.962 2.337    1.00 74.85  ? 22  ALA A N     1 
ATOM   142   C CA    . ALA A 1 22  ? -14.271 -31.269 2.615    1.00 73.15  ? 22  ALA A CA    1 
ATOM   143   C C     . ALA A 1 22  ? -14.154 -31.563 4.099    1.00 59.92  ? 22  ALA A C     1 
ATOM   144   O O     . ALA A 1 22  ? -14.966 -32.313 4.619    1.00 64.34  ? 22  ALA A O     1 
ATOM   145   C CB    . ALA A 1 22  ? -13.602 -32.343 1.801    1.00 82.23  ? 22  ALA A CB    1 
ATOM   146   N N     . ARG A 1 23  ? -13.153 -30.960 4.745    1.00 58.42  ? 23  ARG A N     1 
ATOM   147   C CA    . ARG A 1 23  ? -13.013 -31.037 6.188    1.00 72.04  ? 23  ARG A CA    1 
ATOM   148   C C     . ARG A 1 23  ? -14.153 -30.244 6.819    1.00 73.33  ? 23  ARG A C     1 
ATOM   149   O O     . ARG A 1 23  ? -14.654 -30.620 7.877    1.00 68.53  ? 23  ARG A O     1 
ATOM   150   C CB    . ARG A 1 23  ? -11.646 -30.513 6.661    1.00 78.56  ? 23  ARG A CB    1 
ATOM   151   C CG    . ARG A 1 23  ? -10.528 -31.548 6.671    1.00 93.98  ? 23  ARG A CG    1 
ATOM   152   C CD    . ARG A 1 23  ? -9.118  -30.978 6.530    1.00 104.82 ? 23  ARG A CD    1 
ATOM   153   N NE    . ARG A 1 23  ? -8.178  -31.986 6.016    1.00 112.19 ? 23  ARG A NE    1 
ATOM   154   C CZ    . ARG A 1 23  ? -7.542  -31.970 4.835    1.00 103.92 ? 23  ARG A CZ    1 
ATOM   155   N NH1   . ARG A 1 23  ? -7.583  -30.925 4.027    1.00 91.11  ? 23  ARG A NH1   1 
ATOM   156   N NH2   . ARG A 1 23  ? -6.826  -33.018 4.466    1.00 109.08 ? 23  ARG A NH2   1 
ATOM   157   N N     . ILE A 1 24  ? -14.539 -29.138 6.163    1.00 66.66  ? 24  ILE A N     1 
ATOM   158   C CA    . ILE A 1 24  ? -15.494 -28.209 6.738    1.00 55.35  ? 24  ILE A CA    1 
ATOM   159   C C     . ILE A 1 24  ? -16.894 -28.793 6.679    1.00 53.81  ? 24  ILE A C     1 
ATOM   160   O O     . ILE A 1 24  ? -17.603 -28.719 7.671    1.00 58.13  ? 24  ILE A O     1 
ATOM   161   C CB    . ILE A 1 24  ? -15.450 -26.834 6.051    1.00 57.13  ? 24  ILE A CB    1 
ATOM   162   C CG1   . ILE A 1 24  ? -14.189 -26.062 6.435    1.00 51.69  ? 24  ILE A CG1   1 
ATOM   163   C CG2   . ILE A 1 24  ? -16.706 -26.031 6.382    1.00 59.24  ? 24  ILE A CG2   1 
ATOM   164   C CD1   . ILE A 1 24  ? -13.805 -25.002 5.424    1.00 56.68  ? 24  ILE A CD1   1 
ATOM   165   N N     . VAL A 1 25  ? -17.303 -29.335 5.525    1.00 54.62  ? 25  VAL A N     1 
ATOM   166   C CA    . VAL A 1 25  ? -18.688 -29.749 5.358    1.00 56.84  ? 25  VAL A CA    1 
ATOM   167   C C     . VAL A 1 25  ? -18.798 -31.263 5.397    1.00 58.92  ? 25  VAL A C     1 
ATOM   168   O O     . VAL A 1 25  ? -19.899 -31.792 5.309    1.00 68.46  ? 25  VAL A O     1 
ATOM   169   C CB    . VAL A 1 25  ? -19.293 -29.186 4.059    1.00 63.96  ? 25  VAL A CB    1 
ATOM   170   C CG1   . VAL A 1 25  ? -19.194 -27.661 4.024    1.00 64.02  ? 25  VAL A CG1   1 
ATOM   171   C CG2   . VAL A 1 25  ? -18.674 -29.793 2.808    1.00 64.09  ? 25  VAL A CG2   1 
ATOM   172   N N     . GLY A 1 26  ? -17.657 -31.950 5.501    1.00 69.35  ? 26  GLY A N     1 
ATOM   173   C CA    . GLY A 1 26  ? -17.620 -33.396 5.357    1.00 75.08  ? 26  GLY A CA    1 
ATOM   174   C C     . GLY A 1 26  ? -17.531 -33.804 3.890    1.00 76.42  ? 26  GLY A C     1 
ATOM   175   O O     . GLY A 1 26  ? -18.128 -33.158 3.029    1.00 63.74  ? 26  GLY A O     1 
ATOM   176   N N     . ALA A 1 27  ? -16.829 -34.915 3.634    1.00 78.88  ? 27  ALA A N     1 
ATOM   177   C CA    . ALA A 1 27  ? -16.516 -35.350 2.282    1.00 75.02  ? 27  ALA A CA    1 
ATOM   178   C C     . ALA A 1 27  ? -17.767 -35.578 1.425    1.00 61.36  ? 27  ALA A C     1 
ATOM   179   O O     . ALA A 1 27  ? -17.687 -35.387 0.222    1.00 68.82  ? 27  ALA A O     1 
ATOM   180   C CB    . ALA A 1 27  ? -15.646 -36.579 2.334    1.00 79.77  ? 27  ALA A CB    1 
ATOM   181   N N     . ASP A 1 28  ? -18.922 -35.928 2.008    1.00 64.54  ? 28  ASP A N     1 
ATOM   182   C CA    . ASP A 1 28  ? -20.135 -36.212 1.232    1.00 79.44  ? 28  ASP A CA    1 
ATOM   183   C C     . ASP A 1 28  ? -20.652 -34.998 0.442    1.00 81.33  ? 28  ASP A C     1 
ATOM   184   O O     . ASP A 1 28  ? -21.517 -35.158 -0.423   1.00 84.23  ? 28  ASP A O     1 
ATOM   185   C CB    . ASP A 1 28  ? -21.349 -36.612 2.094    1.00 86.58  ? 28  ASP A CB    1 
ATOM   186   C CG    . ASP A 1 28  ? -21.255 -37.901 2.894    1.00 88.45  ? 28  ASP A CG    1 
ATOM   187   O OD1   . ASP A 1 28  ? -21.053 -38.945 2.270    1.00 84.86  ? 28  ASP A OD1   1 
ATOM   188   O OD2   . ASP A 1 28  ? -21.439 -37.847 4.137    1.00 83.29  ? 28  ASP A OD2   1 
ATOM   189   N N     . TRP A 1 29  ? -20.183 -33.783 0.779    1.00 80.95  ? 29  TRP A N     1 
ATOM   190   C CA    . TRP A 1 29  ? -20.839 -32.543 0.374    1.00 71.79  ? 29  TRP A CA    1 
ATOM   191   C C     . TRP A 1 29  ? -19.921 -31.680 -0.515   1.00 74.95  ? 29  TRP A C     1 
ATOM   192   O O     . TRP A 1 29  ? -20.149 -30.484 -0.690   1.00 67.14  ? 29  TRP A O     1 
ATOM   193   C CB    . TRP A 1 29  ? -21.343 -31.837 1.653    1.00 62.81  ? 29  TRP A CB    1 
ATOM   194   C CG    . TRP A 1 29  ? -22.370 -32.639 2.405    1.00 56.53  ? 29  TRP A CG    1 
ATOM   195   C CD1   . TRP A 1 29  ? -22.227 -33.225 3.638    1.00 52.50  ? 29  TRP A CD1   1 
ATOM   196   C CD2   . TRP A 1 29  ? -23.691 -33.007 1.936    1.00 49.28  ? 29  TRP A CD2   1 
ATOM   197   N NE1   . TRP A 1 29  ? -23.362 -33.926 3.966    1.00 50.25  ? 29  TRP A NE1   1 
ATOM   198   C CE2   . TRP A 1 29  ? -24.280 -33.800 2.946    1.00 48.67  ? 29  TRP A CE2   1 
ATOM   199   C CE3   . TRP A 1 29  ? -24.424 -32.757 0.762    1.00 47.75  ? 29  TRP A CE3   1 
ATOM   200   C CZ2   . TRP A 1 29  ? -25.569 -34.322 2.813    1.00 45.46  ? 29  TRP A CZ2   1 
ATOM   201   C CZ3   . TRP A 1 29  ? -25.709 -33.254 0.641    1.00 47.16  ? 29  TRP A CZ3   1 
ATOM   202   C CH2   . TRP A 1 29  ? -26.273 -34.028 1.660    1.00 46.55  ? 29  TRP A CH2   1 
ATOM   203   N N     . VAL A 1 30  ? -18.907 -32.314 -1.131   1.00 71.82  ? 30  VAL A N     1 
ATOM   204   C CA    . VAL A 1 30  ? -18.068 -31.704 -2.148   1.00 67.16  ? 30  VAL A CA    1 
ATOM   205   C C     . VAL A 1 30  ? -18.209 -32.504 -3.437   1.00 66.78  ? 30  VAL A C     1 
ATOM   206   O O     . VAL A 1 30  ? -17.940 -33.693 -3.447   1.00 82.82  ? 30  VAL A O     1 
ATOM   207   C CB    . VAL A 1 30  ? -16.604 -31.652 -1.692   1.00 69.01  ? 30  VAL A CB    1 
ATOM   208   C CG1   . VAL A 1 30  ? -15.716 -31.022 -2.750   1.00 72.78  ? 30  VAL A CG1   1 
ATOM   209   C CG2   . VAL A 1 30  ? -16.448 -30.916 -0.370   1.00 69.65  ? 30  VAL A CG2   1 
ATOM   210   N N     . PHE A 1 31  ? -18.646 -31.845 -4.515   1.00 75.85  ? 31  PHE A N     1 
ATOM   211   C CA    . PHE A 1 31  ? -19.079 -32.495 -5.747   1.00 71.71  ? 31  PHE A CA    1 
ATOM   212   C C     . PHE A 1 31  ? -18.143 -32.129 -6.901   1.00 72.29  ? 31  PHE A C     1 
ATOM   213   O O     . PHE A 1 31  ? -17.827 -30.961 -7.089   1.00 66.84  ? 31  PHE A O     1 
ATOM   214   C CB    . PHE A 1 31  ? -20.487 -32.043 -6.143   1.00 69.83  ? 31  PHE A CB    1 
ATOM   215   C CG    . PHE A 1 31  ? -21.575 -32.207 -5.109   1.00 82.44  ? 31  PHE A CG    1 
ATOM   216   C CD1   . PHE A 1 31  ? -21.389 -32.955 -3.954   1.00 87.81  ? 31  PHE A CD1   1 
ATOM   217   C CD2   . PHE A 1 31  ? -22.809 -31.597 -5.303   1.00 95.13  ? 31  PHE A CD2   1 
ATOM   218   C CE1   . PHE A 1 31  ? -22.417 -33.101 -3.032   1.00 91.86  ? 31  PHE A CE1   1 
ATOM   219   C CE2   . PHE A 1 31  ? -23.835 -31.735 -4.377   1.00 96.12  ? 31  PHE A CE2   1 
ATOM   220   C CZ    . PHE A 1 31  ? -23.638 -32.494 -3.244   1.00 98.25  ? 31  PHE A CZ    1 
ATOM   221   N N     . THR A 1 32  ? -17.738 -33.134 -7.691   1.00 85.92  ? 32  THR A N     1 
ATOM   222   C CA    . THR A 1 32  ? -16.853 -32.964 -8.839   1.00 88.53  ? 32  THR A CA    1 
ATOM   223   C C     . THR A 1 32  ? -17.423 -33.754 -10.021  1.00 93.39  ? 32  THR A C     1 
ATOM   224   O O     . THR A 1 32  ? -18.431 -34.437 -9.858   1.00 85.83  ? 32  THR A O     1 
ATOM   225   C CB    . THR A 1 32  ? -15.416 -33.385 -8.486   1.00 80.50  ? 32  THR A CB    1 
ATOM   226   O OG1   . THR A 1 32  ? -15.491 -34.559 -7.682   1.00 69.37  ? 32  THR A OG1   1 
ATOM   227   C CG2   . THR A 1 32  ? -14.639 -32.348 -7.705   1.00 81.78  ? 32  THR A CG2   1 
ATOM   228   N N     . GLU A 1 33  ? -16.811 -33.598 -11.210  1.00 105.89 ? 33  GLU A N     1 
ATOM   229   C CA    . GLU A 1 33  ? -16.911 -34.542 -12.322  1.00 105.11 ? 33  GLU A CA    1 
ATOM   230   C C     . GLU A 1 33  ? -18.367 -34.733 -12.759  1.00 106.24 ? 33  GLU A C     1 
ATOM   231   O O     . GLU A 1 33  ? -18.933 -33.805 -13.324  1.00 109.06 ? 33  GLU A O     1 
ATOM   232   C CB    . GLU A 1 33  ? -16.165 -35.832 -11.962  1.00 105.62 ? 33  GLU A CB    1 
ATOM   233   C CG    . GLU A 1 33  ? -14.653 -35.677 -12.070  1.00 116.63 ? 33  GLU A CG    1 
ATOM   234   C CD    . GLU A 1 33  ? -13.842 -36.160 -10.877  1.00 119.21 ? 33  GLU A CD    1 
ATOM   235   O OE1   . GLU A 1 33  ? -12.944 -35.401 -10.430  1.00 118.18 ? 33  GLU A OE1   1 
ATOM   236   O OE2   . GLU A 1 33  ? -14.115 -37.279 -10.384  1.00 101.64 ? 33  GLU A OE2   1 
ATOM   237   N N     . ASP A 1 34  ? -18.957 -35.920 -12.525  1.00 113.72 ? 34  ASP A N     1 
ATOM   238   C CA    . ASP A 1 34  ? -20.263 -36.288 -13.079  1.00 122.79 ? 34  ASP A CA    1 
ATOM   239   C C     . ASP A 1 34  ? -21.420 -35.807 -12.200  1.00 115.08 ? 34  ASP A C     1 
ATOM   240   O O     . ASP A 1 34  ? -22.574 -35.779 -12.637  1.00 102.62 ? 34  ASP A O     1 
ATOM   241   C CB    . ASP A 1 34  ? -20.435 -37.807 -13.240  1.00 135.53 ? 34  ASP A CB    1 
ATOM   242   C CG    . ASP A 1 34  ? -20.112 -38.370 -14.617  1.00 131.51 ? 34  ASP A CG    1 
ATOM   243   O OD1   . ASP A 1 34  ? -20.556 -37.772 -15.628  1.00 106.07 ? 34  ASP A OD1   1 
ATOM   244   O OD2   . ASP A 1 34  ? -19.457 -39.438 -14.666  1.00 129.72 ? 34  ASP A OD2   1 
ATOM   245   N N     . LYS A 1 35  ? -21.106 -35.446 -10.953  1.00 109.12 ? 35  LYS A N     1 
ATOM   246   C CA    . LYS A 1 35  ? -22.087 -34.961 -9.996   1.00 105.90 ? 35  LYS A CA    1 
ATOM   247   C C     . LYS A 1 35  ? -22.541 -33.525 -10.316  1.00 103.58 ? 35  LYS A C     1 
ATOM   248   O O     . LYS A 1 35  ? -23.518 -33.058 -9.723   1.00 87.29  ? 35  LYS A O     1 
ATOM   249   C CB    . LYS A 1 35  ? -21.462 -35.080 -8.599   1.00 111.24 ? 35  LYS A CB    1 
ATOM   250   C CG    . LYS A 1 35  ? -21.594 -36.435 -7.906   1.00 109.53 ? 35  LYS A CG    1 
ATOM   251   C CD    . LYS A 1 35  ? -22.419 -36.342 -6.622   1.00 111.93 ? 35  LYS A CD    1 
ATOM   252   C CE    . LYS A 1 35  ? -22.557 -37.635 -5.845   1.00 100.29 ? 35  LYS A CE    1 
ATOM   253   N NZ    . LYS A 1 35  ? -23.730 -38.409 -6.316   1.00 95.61  ? 35  LYS A NZ    1 
ATOM   254   N N     . ILE A 1 36  ? -21.884 -32.861 -11.295  1.00 107.66 ? 36  ILE A N     1 
ATOM   255   C CA    . ILE A 1 36  ? -21.914 -31.408 -11.473  1.00 101.76 ? 36  ILE A CA    1 
ATOM   256   C C     . ILE A 1 36  ? -22.883 -30.975 -12.580  1.00 88.41  ? 36  ILE A C     1 
ATOM   257   O O     . ILE A 1 36  ? -22.879 -29.800 -12.940  1.00 77.66  ? 36  ILE A O     1 
ATOM   258   C CB    . ILE A 1 36  ? -20.493 -30.855 -11.767  1.00 96.90  ? 36  ILE A CB    1 
ATOM   259   C CG1   . ILE A 1 36  ? -20.290 -29.436 -11.229  1.00 92.39  ? 36  ILE A CG1   1 
ATOM   260   C CG2   . ILE A 1 36  ? -20.140 -30.924 -13.251  1.00 94.47  ? 36  ILE A CG2   1 
ATOM   261   C CD1   . ILE A 1 36  ? -20.054 -29.377 -9.746   1.00 90.79  ? 36  ILE A CD1   1 
ATOM   262   N N     . THR A 1 37  ? -23.683 -31.893 -13.145  1.00 86.27  ? 37  THR A N     1 
ATOM   263   C CA    . THR A 1 37  ? -24.518 -31.551 -14.293  1.00 93.02  ? 37  THR A CA    1 
ATOM   264   C C     . THR A 1 37  ? -25.854 -30.938 -13.846  1.00 90.34  ? 37  THR A C     1 
ATOM   265   O O     . THR A 1 37  ? -26.429 -30.133 -14.587  1.00 72.97  ? 37  THR A O     1 
ATOM   266   C CB    . THR A 1 37  ? -24.610 -32.719 -15.292  1.00 91.96  ? 37  THR A CB    1 
ATOM   267   O OG1   . THR A 1 37  ? -24.323 -33.920 -14.579  1.00 97.66  ? 37  THR A OG1   1 
ATOM   268   C CG2   . THR A 1 37  ? -23.637 -32.607 -16.452  1.00 85.54  ? 37  THR A CG2   1 
ATOM   269   N N     . PRO A 1 38  ? -26.407 -31.227 -12.638  1.00 90.30  ? 38  PRO A N     1 
ATOM   270   C CA    . PRO A 1 38  ? -27.446 -30.359 -12.072  1.00 81.53  ? 38  PRO A CA    1 
ATOM   271   C C     . PRO A 1 38  ? -27.135 -28.853 -12.146  1.00 75.05  ? 38  PRO A C     1 
ATOM   272   O O     . PRO A 1 38  ? -28.058 -28.056 -12.297  1.00 62.09  ? 38  PRO A O     1 
ATOM   273   C CB    . PRO A 1 38  ? -27.554 -30.851 -10.612  1.00 79.51  ? 38  PRO A CB    1 
ATOM   274   C CG    . PRO A 1 38  ? -27.180 -32.323 -10.678  1.00 77.25  ? 38  PRO A CG    1 
ATOM   275   C CD    . PRO A 1 38  ? -26.153 -32.412 -11.795  1.00 82.12  ? 38  PRO A CD    1 
ATOM   276   N N     . TYR A 1 39  ? -25.849 -28.455 -12.058  1.00 70.75  ? 39  TYR A N     1 
ATOM   277   C CA    . TYR A 1 39  ? -25.465 -27.046 -11.951  1.00 76.80  ? 39  TYR A CA    1 
ATOM   278   C C     . TYR A 1 39  ? -25.070 -26.430 -13.296  1.00 73.08  ? 39  TYR A C     1 
ATOM   279   O O     . TYR A 1 39  ? -24.462 -25.362 -13.303  1.00 66.11  ? 39  TYR A O     1 
ATOM   280   C CB    . TYR A 1 39  ? -24.291 -26.849 -10.983  1.00 74.12  ? 39  TYR A CB    1 
ATOM   281   C CG    . TYR A 1 39  ? -24.523 -27.388 -9.598   1.00 75.26  ? 39  TYR A CG    1 
ATOM   282   C CD1   . TYR A 1 39  ? -25.394 -26.757 -8.723   1.00 77.81  ? 39  TYR A CD1   1 
ATOM   283   C CD2   . TYR A 1 39  ? -23.899 -28.549 -9.171   1.00 74.35  ? 39  TYR A CD2   1 
ATOM   284   C CE1   . TYR A 1 39  ? -25.624 -27.254 -7.449   1.00 78.12  ? 39  TYR A CE1   1 
ATOM   285   C CE2   . TYR A 1 39  ? -24.124 -29.065 -7.906   1.00 76.85  ? 39  TYR A CE2   1 
ATOM   286   C CZ    . TYR A 1 39  ? -24.987 -28.411 -7.042   1.00 80.03  ? 39  TYR A CZ    1 
ATOM   287   O OH    . TYR A 1 39  ? -25.206 -28.909 -5.793   1.00 83.99  ? 39  TYR A OH    1 
ATOM   288   N N     . GLU A 1 40  ? -25.374 -27.111 -14.414  1.00 76.69  ? 40  GLU A N     1 
ATOM   289   C CA    . GLU A 1 40  ? -25.246 -26.532 -15.744  1.00 73.50  ? 40  GLU A CA    1 
ATOM   290   C C     . GLU A 1 40  ? -26.441 -25.626 -16.002  1.00 76.16  ? 40  GLU A C     1 
ATOM   291   O O     . GLU A 1 40  ? -27.528 -25.847 -15.469  1.00 66.74  ? 40  GLU A O     1 
ATOM   292   C CB    . GLU A 1 40  ? -25.282 -27.576 -16.870  1.00 76.11  ? 40  GLU A CB    1 
ATOM   293   C CG    . GLU A 1 40  ? -24.154 -28.588 -16.869  1.00 79.00  ? 40  GLU A CG    1 
ATOM   294   C CD    . GLU A 1 40  ? -22.783 -27.968 -16.690  1.00 79.36  ? 40  GLU A CD    1 
ATOM   295   O OE1   . GLU A 1 40  ? -22.491 -26.949 -17.360  1.00 73.97  ? 40  GLU A OE1   1 
ATOM   296   O OE2   . GLU A 1 40  ? -22.024 -28.493 -15.865  1.00 91.51  ? 40  GLU A OE2   1 
ATOM   297   N N     . ASP A 1 41  ? -26.236 -24.640 -16.873  1.00 78.44  ? 41  ASP A N     1 
ATOM   298   C CA    . ASP A 1 41  ? -27.348 -23.927 -17.475  1.00 83.72  ? 41  ASP A CA    1 
ATOM   299   C C     . ASP A 1 41  ? -28.283 -24.950 -18.148  1.00 85.01  ? 41  ASP A C     1 
ATOM   300   O O     . ASP A 1 41  ? -27.866 -25.606 -19.102  1.00 70.37  ? 41  ASP A O     1 
ATOM   301   C CB    . ASP A 1 41  ? -26.775 -22.863 -18.421  1.00 84.40  ? 41  ASP A CB    1 
ATOM   302   C CG    . ASP A 1 41  ? -27.747 -21.791 -18.893  1.00 83.41  ? 41  ASP A CG    1 
ATOM   303   O OD1   . ASP A 1 41  ? -28.989 -21.874 -18.545  1.00 57.45  ? 41  ASP A OD1   1 
ATOM   304   O OD2   . ASP A 1 41  ? -27.254 -20.873 -19.607  1.00 86.97  ? 41  ASP A OD2   1 
ATOM   305   N N     . PRO A 1 42  ? -29.559 -25.140 -17.693  1.00 95.50  ? 42  PRO A N     1 
ATOM   306   C CA    . PRO A 1 42  ? -30.508 -26.037 -18.375  1.00 84.42  ? 42  PRO A CA    1 
ATOM   307   C C     . PRO A 1 42  ? -31.019 -25.556 -19.737  1.00 85.64  ? 42  PRO A C     1 
ATOM   308   O O     . PRO A 1 42  ? -31.381 -26.379 -20.580  1.00 86.42  ? 42  PRO A O     1 
ATOM   309   C CB    . PRO A 1 42  ? -31.704 -26.124 -17.410  1.00 81.56  ? 42  PRO A CB    1 
ATOM   310   C CG    . PRO A 1 42  ? -31.650 -24.814 -16.627  1.00 88.96  ? 42  PRO A CG    1 
ATOM   311   C CD    . PRO A 1 42  ? -30.168 -24.511 -16.500  1.00 95.76  ? 42  PRO A CD    1 
ATOM   312   N N     . TYR A 1 43  ? -31.079 -24.225 -19.928  1.00 84.22  ? 43  TYR A N     1 
ATOM   313   C CA    . TYR A 1 43  ? -31.447 -23.622 -21.205  1.00 82.74  ? 43  TYR A CA    1 
ATOM   314   C C     . TYR A 1 43  ? -30.194 -23.029 -21.869  1.00 86.40  ? 43  TYR A C     1 
ATOM   315   O O     . TYR A 1 43  ? -29.959 -21.818 -21.779  1.00 82.58  ? 43  TYR A O     1 
ATOM   316   C CB    . TYR A 1 43  ? -32.576 -22.588 -21.037  1.00 75.67  ? 43  TYR A CB    1 
ATOM   317   C CG    . TYR A 1 43  ? -33.796 -23.028 -20.252  1.00 80.55  ? 43  TYR A CG    1 
ATOM   318   C CD1   . TYR A 1 43  ? -34.299 -24.327 -20.318  1.00 80.37  ? 43  TYR A CD1   1 
ATOM   319   C CD2   . TYR A 1 43  ? -34.498 -22.119 -19.470  1.00 77.79  ? 43  TYR A CD2   1 
ATOM   320   C CE1   . TYR A 1 43  ? -35.427 -24.711 -19.600  1.00 77.45  ? 43  TYR A CE1   1 
ATOM   321   C CE2   . TYR A 1 43  ? -35.623 -22.488 -18.747  1.00 74.08  ? 43  TYR A CE2   1 
ATOM   322   C CZ    . TYR A 1 43  ? -36.089 -23.792 -18.803  1.00 77.57  ? 43  TYR A CZ    1 
ATOM   323   O OH    . TYR A 1 43  ? -37.211 -24.139 -18.083  1.00 75.29  ? 43  TYR A OH    1 
ATOM   324   N N     . THR A 1 44  ? -29.413 -23.907 -22.539  1.00 90.43  ? 44  THR A N     1 
ATOM   325   C CA    . THR A 1 44  ? -28.198 -23.557 -23.279  1.00 87.06  ? 44  THR A CA    1 
ATOM   326   C C     . THR A 1 44  ? -28.505 -22.431 -24.277  1.00 79.60  ? 44  THR A C     1 
ATOM   327   O O     . THR A 1 44  ? -29.481 -22.511 -25.030  1.00 74.47  ? 44  THR A O     1 
ATOM   328   C CB    . THR A 1 44  ? -27.593 -24.783 -24.007  1.00 82.37  ? 44  THR A CB    1 
ATOM   329   O OG1   . THR A 1 44  ? -27.896 -25.963 -23.267  1.00 75.40  ? 44  THR A OG1   1 
ATOM   330   C CG2   . THR A 1 44  ? -26.090 -24.729 -24.229  1.00 71.97  ? 44  THR A CG2   1 
ATOM   331   N N     . ILE A 1 45  ? -27.689 -21.363 -24.240  1.00 74.21  ? 45  ILE A N     1 
ATOM   332   C CA    . ILE A 1 45  ? -27.728 -20.285 -25.222  1.00 77.98  ? 45  ILE A CA    1 
ATOM   333   C C     . ILE A 1 45  ? -26.417 -20.282 -26.014  1.00 73.86  ? 45  ILE A C     1 
ATOM   334   O O     . ILE A 1 45  ? -26.426 -20.015 -27.210  1.00 65.37  ? 45  ILE A O     1 
ATOM   335   C CB    . ILE A 1 45  ? -27.986 -18.912 -24.556  1.00 75.54  ? 45  ILE A CB    1 
ATOM   336   C CG1   . ILE A 1 45  ? -29.292 -18.887 -23.762  1.00 73.21  ? 45  ILE A CG1   1 
ATOM   337   C CG2   . ILE A 1 45  ? -27.947 -17.785 -25.583  1.00 76.54  ? 45  ILE A CG2   1 
ATOM   338   C CD1   . ILE A 1 45  ? -29.355 -17.795 -22.732  1.00 72.72  ? 45  ILE A CD1   1 
ATOM   339   N N     . SER A 1 46  ? -25.294 -20.572 -25.341  1.00 73.63  ? 46  SER A N     1 
ATOM   340   C CA    . SER A 1 46  ? -23.986 -20.542 -25.974  1.00 84.69  ? 46  SER A CA    1 
ATOM   341   C C     . SER A 1 46  ? -23.751 -21.798 -26.820  1.00 92.49  ? 46  SER A C     1 
ATOM   342   O O     . SER A 1 46  ? -24.199 -22.892 -26.454  1.00 96.98  ? 46  SER A O     1 
ATOM   343   C CB    . SER A 1 46  ? -22.910 -20.386 -24.934  1.00 82.57  ? 46  SER A CB    1 
ATOM   344   O OG    . SER A 1 46  ? -21.652 -20.195 -25.565  1.00 77.41  ? 46  SER A OG    1 
ATOM   345   N N     . ASN A 1 47  ? -23.019 -21.626 -27.937  1.00 80.15  ? 47  ASN A N     1 
ATOM   346   C CA    . ASN A 1 47  ? -22.524 -22.739 -28.742  1.00 80.33  ? 47  ASN A CA    1 
ATOM   347   C C     . ASN A 1 47  ? -21.101 -23.133 -28.312  1.00 82.65  ? 47  ASN A C     1 
ATOM   348   O O     . ASN A 1 47  ? -20.601 -24.183 -28.729  1.00 76.83  ? 47  ASN A O     1 
ATOM   349   C CB    . ASN A 1 47  ? -22.616 -22.451 -30.250  1.00 73.87  ? 47  ASN A CB    1 
ATOM   350   C CG    . ASN A 1 47  ? -24.032 -22.533 -30.795  1.00 67.05  ? 47  ASN A CG    1 
ATOM   351   O OD1   . ASN A 1 47  ? -24.802 -23.406 -30.408  1.00 67.43  ? 47  ASN A OD1   1 
ATOM   352   N ND2   . ASN A 1 47  ? -24.399 -21.641 -31.700  1.00 63.54  ? 47  ASN A ND2   1 
ATOM   353   N N     . ASP A 1 48  ? -20.473 -22.317 -27.445  1.00 84.73  ? 48  ASP A N     1 
ATOM   354   C CA    . ASP A 1 48  ? -19.115 -22.544 -26.960  1.00 88.83  ? 48  ASP A CA    1 
ATOM   355   C C     . ASP A 1 48  ? -19.184 -23.261 -25.607  1.00 89.04  ? 48  ASP A C     1 
ATOM   356   O O     . ASP A 1 48  ? -19.748 -22.709 -24.661  1.00 80.79  ? 48  ASP A O     1 
ATOM   357   C CB    . ASP A 1 48  ? -18.376 -21.202 -26.856  1.00 92.28  ? 48  ASP A CB    1 
ATOM   358   C CG    . ASP A 1 48  ? -16.850 -21.250 -26.826  1.00 98.11  ? 48  ASP A CG    1 
ATOM   359   O OD1   . ASP A 1 48  ? -16.270 -21.923 -25.938  1.00 82.55  ? 48  ASP A OD1   1 
ATOM   360   O OD2   . ASP A 1 48  ? -16.241 -20.558 -27.666  1.00 108.30 ? 48  ASP A OD2   1 
ATOM   361   N N     . GLU A 1 49  ? -18.563 -24.454 -25.507  1.00 83.51  ? 49  GLU A N     1 
ATOM   362   C CA    . GLU A 1 49  ? -18.653 -25.310 -24.326  1.00 87.76  ? 49  GLU A CA    1 
ATOM   363   C C     . GLU A 1 49  ? -17.508 -25.089 -23.328  1.00 87.97  ? 49  GLU A C     1 
ATOM   364   O O     . GLU A 1 49  ? -17.140 -26.006 -22.588  1.00 87.87  ? 49  GLU A O     1 
ATOM   365   C CB    . GLU A 1 49  ? -18.693 -26.771 -24.776  1.00 95.76  ? 49  GLU A CB    1 
ATOM   366   C CG    . GLU A 1 49  ? -20.007 -27.139 -25.437  1.00 101.38 ? 49  GLU A CG    1 
ATOM   367   C CD    . GLU A 1 49  ? -20.170 -28.623 -25.695  1.00 101.41 ? 49  GLU A CD    1 
ATOM   368   O OE1   . GLU A 1 49  ? -19.171 -29.351 -25.559  1.00 102.37 ? 49  GLU A OE1   1 
ATOM   369   O OE2   . GLU A 1 49  ? -21.295 -29.041 -26.011  1.00 97.48  ? 49  GLU A OE2   1 
ATOM   370   N N     . THR A 1 50  ? -16.968 -23.864 -23.291  1.00 90.06  ? 50  THR A N     1 
ATOM   371   C CA    . THR A 1 50  ? -15.965 -23.460 -22.313  1.00 91.56  ? 50  THR A CA    1 
ATOM   372   C C     . THR A 1 50  ? -16.518 -22.319 -21.443  1.00 82.52  ? 50  THR A C     1 
ATOM   373   O O     . THR A 1 50  ? -15.794 -21.795 -20.599  1.00 71.96  ? 50  THR A O     1 
ATOM   374   C CB    . THR A 1 50  ? -14.641 -23.096 -23.018  1.00 87.97  ? 50  THR A CB    1 
ATOM   375   O OG1   . THR A 1 50  ? -14.799 -21.902 -23.787  1.00 76.96  ? 50  THR A OG1   1 
ATOM   376   C CG2   . THR A 1 50  ? -14.128 -24.177 -23.949  1.00 82.90  ? 50  THR A CG2   1 
ATOM   377   N N     . GLU A 1 51  ? -17.807 -21.966 -21.635  1.00 78.95  ? 51  GLU A N     1 
ATOM   378   C CA    . GLU A 1 51  ? -18.424 -20.764 -21.078  1.00 87.01  ? 51  GLU A CA    1 
ATOM   379   C C     . GLU A 1 51  ? -19.511 -21.135 -20.063  1.00 82.22  ? 51  GLU A C     1 
ATOM   380   O O     . GLU A 1 51  ? -20.270 -22.081 -20.286  1.00 61.59  ? 51  GLU A O     1 
ATOM   381   C CB    . GLU A 1 51  ? -19.031 -19.892 -22.185  1.00 90.99  ? 51  GLU A CB    1 
ATOM   382   C CG    . GLU A 1 51  ? -18.003 -19.147 -23.031  1.00 98.25  ? 51  GLU A CG    1 
ATOM   383   C CD    . GLU A 1 51  ? -18.555 -18.254 -24.137  1.00 99.93  ? 51  GLU A CD    1 
ATOM   384   O OE1   . GLU A 1 51  ? -19.794 -18.127 -24.265  1.00 94.91  ? 51  GLU A OE1   1 
ATOM   385   O OE2   . GLU A 1 51  ? -17.738 -17.681 -24.877  1.00 100.07 ? 51  GLU A OE2   1 
ATOM   386   N N     . HIS A 1 52  ? -19.586 -20.371 -18.957  1.00 75.49  ? 52  HIS A N     1 
ATOM   387   C CA    . HIS A 1 52  ? -20.509 -20.660 -17.869  1.00 76.88  ? 52  HIS A CA    1 
ATOM   388   C C     . HIS A 1 52  ? -20.450 -22.133 -17.428  1.00 86.14  ? 52  HIS A C     1 
ATOM   389   O O     . HIS A 1 52  ? -21.502 -22.750 -17.218  1.00 77.32  ? 52  HIS A O     1 
ATOM   390   C CB    . HIS A 1 52  ? -21.936 -20.289 -18.286  1.00 72.64  ? 52  HIS A CB    1 
ATOM   391   C CG    . HIS A 1 52  ? -21.952 -19.163 -19.239  1.00 70.86  ? 52  HIS A CG    1 
ATOM   392   N ND1   . HIS A 1 52  ? -21.294 -17.986 -18.978  1.00 81.74  ? 52  HIS A ND1   1 
ATOM   393   C CD2   . HIS A 1 52  ? -22.487 -19.041 -20.450  1.00 80.85  ? 52  HIS A CD2   1 
ATOM   394   C CE1   . HIS A 1 52  ? -21.463 -17.165 -20.001  1.00 89.69  ? 52  HIS A CE1   1 
ATOM   395   N NE2   . HIS A 1 52  ? -22.179 -17.791 -20.911  1.00 94.86  ? 52  HIS A NE2   1 
ATOM   396   N N     . ARG A 1 53  ? -19.223 -22.674 -17.268  1.00 87.40  ? 53  ARG A N     1 
ATOM   397   C CA    . ARG A 1 53  ? -18.987 -24.047 -16.830  1.00 83.63  ? 53  ARG A CA    1 
ATOM   398   C C     . ARG A 1 53  ? -18.489 -24.058 -15.381  1.00 82.21  ? 53  ARG A C     1 
ATOM   399   O O     . ARG A 1 53  ? -17.349 -23.676 -15.106  1.00 83.88  ? 53  ARG A O     1 
ATOM   400   C CB    . ARG A 1 53  ? -17.976 -24.759 -17.738  1.00 83.41  ? 53  ARG A CB    1 
ATOM   401   C CG    . ARG A 1 53  ? -18.316 -24.716 -19.222  1.00 92.51  ? 53  ARG A CG    1 
ATOM   402   C CD    . ARG A 1 53  ? -19.777 -24.989 -19.571  1.00 91.14  ? 53  ARG A CD    1 
ATOM   403   N NE    . ARG A 1 53  ? -20.202 -26.355 -19.297  1.00 102.35 ? 53  ARG A NE    1 
ATOM   404   C CZ    . ARG A 1 53  ? -19.836 -27.432 -19.993  1.00 99.94  ? 53  ARG A CZ    1 
ATOM   405   N NH1   . ARG A 1 53  ? -19.094 -27.312 -21.083  1.00 96.56  ? 53  ARG A NH1   1 
ATOM   406   N NH2   . ARG A 1 53  ? -20.229 -28.632 -19.593  1.00 87.16  ? 53  ARG A NH2   1 
ATOM   407   N N     . PRO A 1 54  ? -19.331 -24.495 -14.409  1.00 70.33  ? 54  PRO A N     1 
ATOM   408   C CA    . PRO A 1 54  ? -18.890 -24.678 -13.021  1.00 57.80  ? 54  PRO A CA    1 
ATOM   409   C C     . PRO A 1 54  ? -17.953 -25.858 -12.821  1.00 57.65  ? 54  PRO A C     1 
ATOM   410   O O     . PRO A 1 54  ? -18.171 -26.898 -13.442  1.00 64.54  ? 54  PRO A O     1 
ATOM   411   C CB    . PRO A 1 54  ? -20.191 -24.975 -12.273  1.00 62.21  ? 54  PRO A CB    1 
ATOM   412   C CG    . PRO A 1 54  ? -21.111 -25.554 -13.333  1.00 67.68  ? 54  PRO A CG    1 
ATOM   413   C CD    . PRO A 1 54  ? -20.760 -24.811 -14.603  1.00 62.08  ? 54  PRO A CD    1 
ATOM   414   N N     . TYR A 1 55  ? -16.971 -25.697 -11.914  1.00 50.78  ? 55  TYR A N     1 
ATOM   415   C CA    . TYR A 1 55  ? -15.870 -26.638 -11.762  1.00 57.42  ? 55  TYR A CA    1 
ATOM   416   C C     . TYR A 1 55  ? -16.096 -27.644 -10.633  1.00 67.24  ? 55  TYR A C     1 
ATOM   417   O O     . TYR A 1 55  ? -15.570 -28.747 -10.704  1.00 66.38  ? 55  TYR A O     1 
ATOM   418   C CB    . TYR A 1 55  ? -14.566 -25.922 -11.400  1.00 60.46  ? 55  TYR A CB    1 
ATOM   419   C CG    . TYR A 1 55  ? -13.392 -26.853 -11.202  1.00 72.02  ? 55  TYR A CG    1 
ATOM   420   C CD1   . TYR A 1 55  ? -12.633 -27.316 -12.273  1.00 84.81  ? 55  TYR A CD1   1 
ATOM   421   C CD2   . TYR A 1 55  ? -13.063 -27.318 -9.941   1.00 79.51  ? 55  TYR A CD2   1 
ATOM   422   C CE1   . TYR A 1 55  ? -11.561 -28.181 -12.087  1.00 83.42  ? 55  TYR A CE1   1 
ATOM   423   C CE2   . TYR A 1 55  ? -11.996 -28.178 -9.734   1.00 84.30  ? 55  TYR A CE2   1 
ATOM   424   C CZ    . TYR A 1 55  ? -11.245 -28.613 -10.809  1.00 82.56  ? 55  TYR A CZ    1 
ATOM   425   O OH    . TYR A 1 55  ? -10.211 -29.468 -10.546  1.00 86.74  ? 55  TYR A OH    1 
ATOM   426   N N     . ALA A 1 56  ? -16.738 -27.202 -9.538   1.00 73.74  ? 56  ALA A N     1 
ATOM   427   C CA    . ALA A 1 56  ? -17.077 -28.050 -8.395   1.00 65.81  ? 56  ALA A CA    1 
ATOM   428   C C     . ALA A 1 56  ? -18.263 -27.432 -7.642   1.00 60.06  ? 56  ALA A C     1 
ATOM   429   O O     . ALA A 1 56  ? -18.720 -26.354 -7.994   1.00 56.89  ? 56  ALA A O     1 
ATOM   430   C CB    . ALA A 1 56  ? -15.875 -28.243 -7.499   1.00 52.90  ? 56  ALA A CB    1 
ATOM   431   N N     . ALA A 1 57  ? -18.811 -28.141 -6.655   1.00 50.10  ? 57  ALA A N     1 
ATOM   432   C CA    . ALA A 1 57  ? -19.840 -27.580 -5.798   1.00 50.46  ? 57  ALA A CA    1 
ATOM   433   C C     . ALA A 1 57  ? -19.566 -27.988 -4.361   1.00 51.38  ? 57  ALA A C     1 
ATOM   434   O O     . ALA A 1 57  ? -19.016 -29.056 -4.136   1.00 60.90  ? 57  ALA A O     1 
ATOM   435   C CB    . ALA A 1 57  ? -21.210 -28.017 -6.221   1.00 51.79  ? 57  ALA A CB    1 
ATOM   436   N N     . VAL A 1 58  ? -19.876 -27.093 -3.412   1.00 60.42  ? 58  VAL A N     1 
ATOM   437   C CA    . VAL A 1 58  ? -19.762 -27.354 -1.977   1.00 57.04  ? 58  VAL A CA    1 
ATOM   438   C C     . VAL A 1 58  ? -21.076 -26.929 -1.328   1.00 53.04  ? 58  VAL A C     1 
ATOM   439   O O     . VAL A 1 58  ? -21.657 -25.918 -1.709   1.00 67.28  ? 58  VAL A O     1 
ATOM   440   C CB    . VAL A 1 58  ? -18.540 -26.659 -1.347   1.00 61.14  ? 58  VAL A CB    1 
ATOM   441   C CG1   . VAL A 1 58  ? -18.527 -25.160 -1.590   1.00 76.13  ? 58  VAL A CG1   1 
ATOM   442   C CG2   . VAL A 1 58  ? -18.436 -26.928 0.144    1.00 65.27  ? 58  VAL A CG2   1 
ATOM   443   N N     . ALA A 1 59  ? -21.592 -27.753 -0.416   1.00 49.20  ? 59  ALA A N     1 
ATOM   444   C CA    . ALA A 1 59  ? -22.941 -27.567 0.097    1.00 42.97  ? 59  ALA A CA    1 
ATOM   445   C C     . ALA A 1 59  ? -22.912 -27.523 1.618    1.00 44.32  ? 59  ALA A C     1 
ATOM   446   O O     . ALA A 1 59  ? -23.071 -28.548 2.252    1.00 46.66  ? 59  ALA A O     1 
ATOM   447   C CB    . ALA A 1 59  ? -23.823 -28.680 -0.387   1.00 39.23  ? 59  ALA A CB    1 
ATOM   448   N N     . PRO A 1 60  ? -22.752 -26.346 2.259    1.00 51.43  ? 60  PRO A N     1 
ATOM   449   C CA    . PRO A 1 60  ? -22.630 -26.290 3.717    1.00 50.28  ? 60  PRO A CA    1 
ATOM   450   C C     . PRO A 1 60  ? -23.969 -26.432 4.443    1.00 48.59  ? 60  PRO A C     1 
ATOM   451   O O     . PRO A 1 60  ? -25.054 -26.395 3.836    1.00 44.13  ? 60  PRO A O     1 
ATOM   452   C CB    . PRO A 1 60  ? -21.931 -24.933 3.952    1.00 50.54  ? 60  PRO A CB    1 
ATOM   453   C CG    . PRO A 1 60  ? -22.300 -24.077 2.753    1.00 51.73  ? 60  PRO A CG    1 
ATOM   454   C CD    . PRO A 1 60  ? -22.705 -25.016 1.635    1.00 52.24  ? 60  PRO A CD    1 
ATOM   455   N N     . ALA A 1 61  ? -23.863 -26.653 5.758    1.00 52.58  ? 61  ALA A N     1 
ATOM   456   C CA    . ALA A 1 61  ? -25.006 -26.987 6.598    1.00 51.36  ? 61  ALA A CA    1 
ATOM   457   C C     . ALA A 1 61  ? -25.458 -25.759 7.383    1.00 53.04  ? 61  ALA A C     1 
ATOM   458   O O     . ALA A 1 61  ? -26.613 -25.689 7.799    1.00 40.54  ? 61  ALA A O     1 
ATOM   459   C CB    . ALA A 1 61  ? -24.641 -28.102 7.543    1.00 43.45  ? 61  ALA A CB    1 
ATOM   460   N N     . SER A 1 62  ? -24.543 -24.794 7.546    1.00 50.27  ? 62  SER A N     1 
ATOM   461   C CA    . SER A 1 62  ? -24.700 -23.760 8.555    1.00 50.10  ? 62  SER A CA    1 
ATOM   462   C C     . SER A 1 62  ? -24.047 -22.462 8.097    1.00 40.05  ? 62  SER A C     1 
ATOM   463   O O     . SER A 1 62  ? -23.238 -22.443 7.197    1.00 49.25  ? 62  SER A O     1 
ATOM   464   C CB    . SER A 1 62  ? -24.091 -24.213 9.858    1.00 48.28  ? 62  SER A CB    1 
ATOM   465   O OG    . SER A 1 62  ? -22.674 -24.081 9.798    1.00 47.91  ? 62  SER A OG    1 
ATOM   466   N N     . THR A 1 63  ? -24.356 -21.372 8.771    1.00 42.12  ? 63  THR A N     1 
ATOM   467   C CA    . THR A 1 63  ? -23.758 -20.088 8.462    1.00 43.48  ? 63  THR A CA    1 
ATOM   468   C C     . THR A 1 63  ? -22.247 -20.181 8.683    1.00 48.90  ? 63  THR A C     1 
ATOM   469   O O     . THR A 1 63  ? -21.466 -19.696 7.858    1.00 54.49  ? 63  THR A O     1 
ATOM   470   C CB    . THR A 1 63  ? -24.452 -18.986 9.282    1.00 41.96  ? 63  THR A CB    1 
ATOM   471   O OG1   . THR A 1 63  ? -25.745 -18.789 8.694    1.00 46.21  ? 63  THR A OG1   1 
ATOM   472   C CG2   . THR A 1 63  ? -23.677 -17.683 9.337    1.00 37.47  ? 63  THR A CG2   1 
ATOM   473   N N     . GLU A 1 64  ? -21.847 -20.827 9.788    1.00 43.86  ? 64  GLU A N     1 
ATOM   474   C CA    . GLU A 1 64  ? -20.450 -20.887 10.191   1.00 46.86  ? 64  GLU A CA    1 
ATOM   475   C C     . GLU A 1 64  ? -19.626 -21.700 9.180    1.00 48.85  ? 64  GLU A C     1 
ATOM   476   O O     . GLU A 1 64  ? -18.463 -21.357 8.946    1.00 47.56  ? 64  GLU A O     1 
ATOM   477   C CB    . GLU A 1 64  ? -20.325 -21.431 11.621   1.00 50.07  ? 64  GLU A CB    1 
ATOM   478   C CG    . GLU A 1 64  ? -19.111 -20.902 12.386   1.00 58.68  ? 64  GLU A CG    1 
ATOM   479   C CD    . GLU A 1 64  ? -17.736 -21.470 12.038   1.00 53.17  ? 64  GLU A CD    1 
ATOM   480   O OE1   . GLU A 1 64  ? -17.638 -22.702 11.925   1.00 47.77  ? 64  GLU A OE1   1 
ATOM   481   O OE2   . GLU A 1 64  ? -16.767 -20.676 11.950   1.00 53.95  ? 64  GLU A OE2   1 
ATOM   482   N N     . GLU A 1 65  ? -20.221 -22.742 8.565    1.00 41.54  ? 65  GLU A N     1 
ATOM   483   C CA    . GLU A 1 65  ? -19.539 -23.492 7.521    1.00 43.88  ? 65  GLU A CA    1 
ATOM   484   C C     . GLU A 1 65  ? -19.302 -22.564 6.329    1.00 46.92  ? 65  GLU A C     1 
ATOM   485   O O     . GLU A 1 65  ? -18.180 -22.492 5.823    1.00 55.09  ? 65  GLU A O     1 
ATOM   486   C CB    . GLU A 1 65  ? -20.267 -24.801 7.178    1.00 47.91  ? 65  GLU A CB    1 
ATOM   487   C CG    . GLU A 1 65  ? -20.196 -25.833 8.305    1.00 52.59  ? 65  GLU A CG    1 
ATOM   488   C CD    . GLU A 1 65  ? -20.917 -27.177 8.172    1.00 61.31  ? 65  GLU A CD    1 
ATOM   489   O OE1   . GLU A 1 65  ? -21.354 -27.536 7.041    1.00 54.34  ? 65  GLU A OE1   1 
ATOM   490   O OE2   . GLU A 1 65  ? -21.024 -27.892 9.226    1.00 57.16  ? 65  GLU A OE2   1 
ATOM   491   N N     . VAL A 1 66  ? -20.322 -21.782 5.943    1.00 47.88  ? 66  VAL A N     1 
ATOM   492   C CA    . VAL A 1 66  ? -20.168 -20.765 4.910    1.00 41.14  ? 66  VAL A CA    1 
ATOM   493   C C     . VAL A 1 66  ? -18.969 -19.869 5.215    1.00 47.15  ? 66  VAL A C     1 
ATOM   494   O O     . VAL A 1 66  ? -18.160 -19.589 4.332    1.00 47.65  ? 66  VAL A O     1 
ATOM   495   C CB    . VAL A 1 66  ? -21.425 -19.892 4.730    1.00 40.46  ? 66  VAL A CB    1 
ATOM   496   C CG1   . VAL A 1 66  ? -21.153 -18.788 3.721    1.00 41.95  ? 66  VAL A CG1   1 
ATOM   497   C CG2   . VAL A 1 66  ? -22.657 -20.688 4.319    1.00 38.99  ? 66  VAL A CG2   1 
ATOM   498   N N     . GLN A 1 67  ? -18.847 -19.374 6.452    1.00 42.05  ? 67  GLN A N     1 
ATOM   499   C CA    . GLN A 1 67  ? -17.759 -18.451 6.702    1.00 45.59  ? 67  GLN A CA    1 
ATOM   500   C C     . GLN A 1 67  ? -16.416 -19.146 6.480    1.00 44.21  ? 67  GLN A C     1 
ATOM   501   O O     . GLN A 1 67  ? -15.456 -18.486 6.078    1.00 46.27  ? 67  GLN A O     1 
ATOM   502   C CB    . GLN A 1 67  ? -17.813 -17.862 8.115    1.00 49.26  ? 67  GLN A CB    1 
ATOM   503   C CG    . GLN A 1 67  ? -19.000 -16.939 8.379    1.00 47.06  ? 67  GLN A CG    1 
ATOM   504   C CD    . GLN A 1 67  ? -19.186 -16.752 9.869    1.00 43.72  ? 67  GLN A CD    1 
ATOM   505   O OE1   . GLN A 1 67  ? -19.983 -17.438 10.496   1.00 46.34  ? 67  GLN A OE1   1 
ATOM   506   N NE2   . GLN A 1 67  ? -18.416 -15.858 10.470   1.00 40.99  ? 67  GLN A NE2   1 
ATOM   507   N N     . GLU A 1 68  ? -16.346 -20.447 6.817    1.00 49.46  ? 68  GLU A N     1 
ATOM   508   C CA    . GLU A 1 68  ? -15.089 -21.191 6.841    1.00 52.25  ? 68  GLU A CA    1 
ATOM   509   C C     . GLU A 1 68  ? -14.651 -21.383 5.390    1.00 52.06  ? 68  GLU A C     1 
ATOM   510   O O     . GLU A 1 68  ? -13.508 -21.077 5.022    1.00 45.21  ? 68  GLU A O     1 
ATOM   511   C CB    . GLU A 1 68  ? -15.240 -22.507 7.613    1.00 49.38  ? 68  GLU A CB    1 
ATOM   512   C CG    . GLU A 1 68  ? -14.942 -22.407 9.112    1.00 60.48  ? 68  GLU A CG    1 
ATOM   513   C CD    . GLU A 1 68  ? -15.039 -23.707 9.921    1.00 63.03  ? 68  GLU A CD    1 
ATOM   514   O OE1   . GLU A 1 68  ? -14.183 -24.607 9.763    1.00 62.03  ? 68  GLU A OE1   1 
ATOM   515   O OE2   . GLU A 1 68  ? -15.986 -23.838 10.715   1.00 65.72  ? 68  GLU A OE2   1 
ATOM   516   N N     . ILE A 1 69  ? -15.613 -21.795 4.554    1.00 41.92  ? 69  ILE A N     1 
ATOM   517   C CA    . ILE A 1 69  ? -15.381 -21.840 3.121    1.00 44.64  ? 69  ILE A CA    1 
ATOM   518   C C     . ILE A 1 69  ? -14.845 -20.501 2.634    1.00 42.88  ? 69  ILE A C     1 
ATOM   519   O O     . ILE A 1 69  ? -13.853 -20.442 1.917    1.00 48.03  ? 69  ILE A O     1 
ATOM   520   C CB    . ILE A 1 69  ? -16.664 -22.230 2.385    1.00 47.06  ? 69  ILE A CB    1 
ATOM   521   C CG1   . ILE A 1 69  ? -16.971 -23.709 2.606    1.00 47.22  ? 69  ILE A CG1   1 
ATOM   522   C CG2   . ILE A 1 69  ? -16.573 -21.864 0.915    1.00 50.13  ? 69  ILE A CG2   1 
ATOM   523   C CD1   . ILE A 1 69  ? -18.419 -24.032 2.490    1.00 47.63  ? 69  ILE A CD1   1 
ATOM   524   N N     . VAL A 1 70  ? -15.500 -19.420 3.021    1.00 40.11  ? 70  VAL A N     1 
ATOM   525   C CA    . VAL A 1 70  ? -15.138 -18.131 2.465    1.00 40.08  ? 70  VAL A CA    1 
ATOM   526   C C     . VAL A 1 70  ? -13.716 -17.796 2.906    1.00 40.57  ? 70  VAL A C     1 
ATOM   527   O O     . VAL A 1 70  ? -12.967 -17.146 2.162    1.00 46.30  ? 70  VAL A O     1 
ATOM   528   C CB    . VAL A 1 70  ? -16.178 -17.040 2.799    1.00 36.25  ? 70  VAL A CB    1 
ATOM   529   C CG1   . VAL A 1 70  ? -15.688 -15.629 2.500    1.00 37.35  ? 70  VAL A CG1   1 
ATOM   530   C CG2   . VAL A 1 70  ? -17.490 -17.297 2.072    1.00 34.77  ? 70  VAL A CG2   1 
ATOM   531   N N     . ARG A 1 71  ? -13.333 -18.226 4.107    1.00 41.41  ? 71  ARG A N     1 
ATOM   532   C CA    . ARG A 1 71  ? -11.999 -17.887 4.578    1.00 44.59  ? 71  ARG A CA    1 
ATOM   533   C C     . ARG A 1 71  ? -10.980 -18.712 3.784    1.00 44.78  ? 71  ARG A C     1 
ATOM   534   O O     . ARG A 1 71  ? -9.948  -18.193 3.374    1.00 43.26  ? 71  ARG A O     1 
ATOM   535   C CB    . ARG A 1 71  ? -11.855 -18.104 6.089    1.00 46.63  ? 71  ARG A CB    1 
ATOM   536   C CG    . ARG A 1 71  ? -12.432 -17.003 6.968    1.00 53.86  ? 71  ARG A CG    1 
ATOM   537   C CD    . ARG A 1 71  ? -12.489 -17.368 8.450    1.00 55.63  ? 71  ARG A CD    1 
ATOM   538   N NE    . ARG A 1 71  ? -13.259 -16.394 9.210    1.00 57.92  ? 71  ARG A NE    1 
ATOM   539   C CZ    . ARG A 1 71  ? -14.176 -16.666 10.143   1.00 59.03  ? 71  ARG A CZ    1 
ATOM   540   N NH1   . ARG A 1 71  ? -14.333 -17.891 10.610   1.00 61.74  ? 71  ARG A NH1   1 
ATOM   541   N NH2   . ARG A 1 71  ? -14.913 -15.682 10.646   1.00 55.93  ? 71  ARG A NH2   1 
ATOM   542   N N     . VAL A 1 72  ? -11.305 -19.992 3.554    1.00 43.22  ? 72  VAL A N     1 
ATOM   543   C CA    . VAL A 1 72  ? -10.493 -20.895 2.754    1.00 44.21  ? 72  VAL A CA    1 
ATOM   544   C C     . VAL A 1 72  ? -10.351 -20.318 1.340    1.00 47.03  ? 72  VAL A C     1 
ATOM   545   O O     . VAL A 1 72  ? -9.237  -20.124 0.842    1.00 43.27  ? 72  VAL A O     1 
ATOM   546   C CB    . VAL A 1 72  ? -11.114 -22.312 2.763    1.00 45.33  ? 72  VAL A CB    1 
ATOM   547   C CG1   . VAL A 1 72  ? -10.726 -23.140 1.540    1.00 42.82  ? 72  VAL A CG1   1 
ATOM   548   C CG2   . VAL A 1 72  ? -10.806 -23.075 4.056    1.00 42.53  ? 72  VAL A CG2   1 
ATOM   549   N N     . ALA A 1 73  ? -11.496 -20.009 0.718    1.00 44.91  ? 73  ALA A N     1 
ATOM   550   C CA    . ALA A 1 73  ? -11.527 -19.456 -0.623   1.00 45.55  ? 73  ALA A CA    1 
ATOM   551   C C     . ALA A 1 73  ? -10.564 -18.286 -0.752   1.00 47.17  ? 73  ALA A C     1 
ATOM   552   O O     . ALA A 1 73  ? -9.928  -18.149 -1.793   1.00 53.53  ? 73  ALA A O     1 
ATOM   553   C CB    . ALA A 1 73  ? -12.924 -19.034 -0.986   1.00 49.49  ? 73  ALA A CB    1 
ATOM   554   N N     . ASN A 1 74  ? -10.459 -17.460 0.298    1.00 45.93  ? 74  ASN A N     1 
ATOM   555   C CA    . ASN A 1 74  ? -9.482  -16.382 0.325    1.00 50.03  ? 74  ASN A CA    1 
ATOM   556   C C     . ASN A 1 74  ? -8.045  -16.931 0.305    1.00 52.25  ? 74  ASN A C     1 
ATOM   557   O O     . ASN A 1 74  ? -7.219  -16.477 -0.477   1.00 54.60  ? 74  ASN A O     1 
ATOM   558   C CB    . ASN A 1 74  ? -9.720  -15.432 1.514    1.00 49.53  ? 74  ASN A CB    1 
ATOM   559   C CG    . ASN A 1 74  ? -10.755 -14.364 1.224    1.00 46.72  ? 74  ASN A CG    1 
ATOM   560   O OD1   . ASN A 1 74  ? -10.437 -13.332 0.649    1.00 47.05  ? 74  ASN A OD1   1 
ATOM   561   N ND2   . ASN A 1 74  ? -12.002 -14.606 1.600    1.00 47.78  ? 74  ASN A ND2   1 
ATOM   562   N N     . GLU A 1 75  ? -7.734  -17.893 1.174    1.00 59.94  ? 75  GLU A N     1 
ATOM   563   C CA    . GLU A 1 75  ? -6.373  -18.383 1.331    1.00 73.85  ? 75  GLU A CA    1 
ATOM   564   C C     . GLU A 1 75  ? -5.808  -18.857 -0.011   1.00 67.78  ? 75  GLU A C     1 
ATOM   565   O O     . GLU A 1 75  ? -4.685  -18.497 -0.356   1.00 62.36  ? 75  GLU A O     1 
ATOM   566   C CB    . GLU A 1 75  ? -6.360  -19.499 2.374    1.00 89.04  ? 75  GLU A CB    1 
ATOM   567   C CG    . GLU A 1 75  ? -5.084  -19.574 3.186    1.00 105.75 ? 75  GLU A CG    1 
ATOM   568   C CD    . GLU A 1 75  ? -5.171  -20.535 4.362    1.00 128.92 ? 75  GLU A CD    1 
ATOM   569   O OE1   . GLU A 1 75  ? -4.113  -20.795 4.971    1.00 126.97 ? 75  GLU A OE1   1 
ATOM   570   O OE2   . GLU A 1 75  ? -6.298  -21.016 4.678    1.00 123.51 ? 75  GLU A OE2   1 
ATOM   571   N N     . PHE A 1 76  ? -6.611  -19.605 -0.786   1.00 58.94  ? 76  PHE A N     1 
ATOM   572   C CA    . PHE A 1 76  ? -6.171  -20.190 -2.051   1.00 60.04  ? 76  PHE A CA    1 
ATOM   573   C C     . PHE A 1 76  ? -6.641  -19.428 -3.293   1.00 55.73  ? 76  PHE A C     1 
ATOM   574   O O     . PHE A 1 76  ? -6.491  -19.946 -4.393   1.00 59.18  ? 76  PHE A O     1 
ATOM   575   C CB    . PHE A 1 76  ? -6.699  -21.620 -2.166   1.00 54.95  ? 76  PHE A CB    1 
ATOM   576   C CG    . PHE A 1 76  ? -6.163  -22.484 -1.070   1.00 62.62  ? 76  PHE A CG    1 
ATOM   577   C CD1   . PHE A 1 76  ? -4.850  -22.937 -1.120   1.00 66.09  ? 76  PHE A CD1   1 
ATOM   578   C CD2   . PHE A 1 76  ? -6.918  -22.744 0.058    1.00 65.00  ? 76  PHE A CD2   1 
ATOM   579   C CE1   . PHE A 1 76  ? -4.320  -23.693 -0.086   1.00 65.56  ? 76  PHE A CE1   1 
ATOM   580   C CE2   . PHE A 1 76  ? -6.386  -23.504 1.090    1.00 74.90  ? 76  PHE A CE2   1 
ATOM   581   C CZ    . PHE A 1 76  ? -5.088  -23.973 1.021    1.00 71.13  ? 76  PHE A CZ    1 
ATOM   582   N N     . GLY A 1 77  ? -7.253  -18.248 -3.124   1.00 50.70  ? 77  GLY A N     1 
ATOM   583   C CA    . GLY A 1 77  ? -7.755  -17.441 -4.226   1.00 42.42  ? 77  GLY A CA    1 
ATOM   584   C C     . GLY A 1 77  ? -8.692  -18.193 -5.164   1.00 43.88  ? 77  GLY A C     1 
ATOM   585   O O     . GLY A 1 77  ? -8.607  -17.976 -6.354   1.00 49.05  ? 77  GLY A O     1 
ATOM   586   N N     . VAL A 1 78  ? -9.593  -19.041 -4.642   1.00 48.97  ? 78  VAL A N     1 
ATOM   587   C CA    . VAL A 1 78  ? -10.586 -19.732 -5.464   1.00 52.48  ? 78  VAL A CA    1 
ATOM   588   C C     . VAL A 1 78  ? -11.926 -18.990 -5.431   1.00 50.60  ? 78  VAL A C     1 
ATOM   589   O O     . VAL A 1 78  ? -12.424 -18.600 -4.384   1.00 52.99  ? 78  VAL A O     1 
ATOM   590   C CB    . VAL A 1 78  ? -10.810 -21.186 -5.002   1.00 55.76  ? 78  VAL A CB    1 
ATOM   591   C CG1   . VAL A 1 78  ? -12.144 -21.745 -5.489   1.00 55.49  ? 78  VAL A CG1   1 
ATOM   592   C CG2   . VAL A 1 78  ? -9.676  -22.102 -5.422   1.00 56.58  ? 78  VAL A CG2   1 
ATOM   593   N N     . PRO A 1 79  ? -12.608 -18.815 -6.573   1.00 49.73  ? 79  PRO A N     1 
ATOM   594   C CA    . PRO A 1 79  ? -13.879 -18.103 -6.588   1.00 48.37  ? 79  PRO A CA    1 
ATOM   595   C C     . PRO A 1 79  ? -15.083 -18.997 -6.329   1.00 49.69  ? 79  PRO A C     1 
ATOM   596   O O     . PRO A 1 79  ? -15.080 -20.175 -6.673   1.00 52.39  ? 79  PRO A O     1 
ATOM   597   C CB    . PRO A 1 79  ? -13.888 -17.525 -8.014   1.00 55.17  ? 79  PRO A CB    1 
ATOM   598   C CG    . PRO A 1 79  ? -13.179 -18.568 -8.838   1.00 52.46  ? 79  PRO A CG    1 
ATOM   599   C CD    . PRO A 1 79  ? -12.136 -19.164 -7.917   1.00 52.02  ? 79  PRO A CD    1 
ATOM   600   N N     . LEU A 1 80  ? -16.105 -18.405 -5.702   1.00 53.12  ? 80  LEU A N     1 
ATOM   601   C CA    . LEU A 1 80  ? -17.316 -19.105 -5.311   1.00 49.86  ? 80  LEU A CA    1 
ATOM   602   C C     . LEU A 1 80  ? -18.488 -18.451 -6.023   1.00 49.40  ? 80  LEU A C     1 
ATOM   603   O O     . LEU A 1 80  ? -18.455 -17.243 -6.281   1.00 47.84  ? 80  LEU A O     1 
ATOM   604   C CB    . LEU A 1 80  ? -17.521 -19.014 -3.793   1.00 48.25  ? 80  LEU A CB    1 
ATOM   605   C CG    . LEU A 1 80  ? -16.374 -19.542 -2.946   1.00 45.29  ? 80  LEU A CG    1 
ATOM   606   C CD1   . LEU A 1 80  ? -16.621 -19.291 -1.475   1.00 45.16  ? 80  LEU A CD1   1 
ATOM   607   C CD2   . LEU A 1 80  ? -16.204 -21.012 -3.201   1.00 46.02  ? 80  LEU A CD2   1 
ATOM   608   N N     . TRP A 1 81  ? -19.510 -19.272 -6.309   1.00 47.15  ? 81  TRP A N     1 
ATOM   609   C CA    . TRP A 1 81  ? -20.720 -18.807 -6.955   1.00 43.87  ? 81  TRP A CA    1 
ATOM   610   C C     . TRP A 1 81  ? -21.902 -19.283 -6.136   1.00 42.83  ? 81  TRP A C     1 
ATOM   611   O O     . TRP A 1 81  ? -22.302 -20.426 -6.297   1.00 44.71  ? 81  TRP A O     1 
ATOM   612   C CB    . TRP A 1 81  ? -20.832 -19.281 -8.417   1.00 43.75  ? 81  TRP A CB    1 
ATOM   613   C CG    . TRP A 1 81  ? -21.919 -18.536 -9.115   1.00 44.05  ? 81  TRP A CG    1 
ATOM   614   C CD1   . TRP A 1 81  ? -23.252 -18.752 -8.990   1.00 48.80  ? 81  TRP A CD1   1 
ATOM   615   C CD2   . TRP A 1 81  ? -21.786 -17.333 -9.884   1.00 45.36  ? 81  TRP A CD2   1 
ATOM   616   N NE1   . TRP A 1 81  ? -23.956 -17.810 -9.684   1.00 54.63  ? 81  TRP A NE1   1 
ATOM   617   C CE2   . TRP A 1 81  ? -23.084 -16.935 -10.255  1.00 47.00  ? 81  TRP A CE2   1 
ATOM   618   C CE3   . TRP A 1 81  ? -20.694 -16.593 -10.345  1.00 48.89  ? 81  TRP A CE3   1 
ATOM   619   C CZ2   . TRP A 1 81  ? -23.336 -15.811 -11.033  1.00 49.74  ? 81  TRP A CZ2   1 
ATOM   620   C CZ3   . TRP A 1 81  ? -20.935 -15.475 -11.109  1.00 49.92  ? 81  TRP A CZ3   1 
ATOM   621   C CH2   . TRP A 1 81  ? -22.239 -15.078 -11.421  1.00 51.27  ? 81  TRP A CH2   1 
ATOM   622   N N     . PRO A 1 82  ? -22.493 -18.442 -5.254   1.00 46.80  ? 82  PRO A N     1 
ATOM   623   C CA    . PRO A 1 82  ? -23.554 -18.871 -4.349   1.00 47.25  ? 82  PRO A CA    1 
ATOM   624   C C     . PRO A 1 82  ? -24.895 -18.946 -5.045   1.00 50.92  ? 82  PRO A C     1 
ATOM   625   O O     . PRO A 1 82  ? -25.268 -18.029 -5.775   1.00 58.94  ? 82  PRO A O     1 
ATOM   626   C CB    . PRO A 1 82  ? -23.671 -17.772 -3.287   1.00 45.60  ? 82  PRO A CB    1 
ATOM   627   C CG    . PRO A 1 82  ? -22.546 -16.819 -3.597   1.00 44.33  ? 82  PRO A CG    1 
ATOM   628   C CD    . PRO A 1 82  ? -22.198 -17.020 -5.056   1.00 48.04  ? 82  PRO A CD    1 
ATOM   629   N N     . VAL A 1 83  ? -25.596 -20.045 -4.783   1.00 60.01  ? 83  VAL A N     1 
ATOM   630   C CA    . VAL A 1 83  ? -26.992 -20.188 -5.154   1.00 60.21  ? 83  VAL A CA    1 
ATOM   631   C C     . VAL A 1 83  ? -27.754 -20.620 -3.904   1.00 62.15  ? 83  VAL A C     1 
ATOM   632   O O     . VAL A 1 83  ? -27.229 -21.393 -3.093   1.00 63.26  ? 83  VAL A O     1 
ATOM   633   C CB    . VAL A 1 83  ? -27.151 -21.206 -6.286   1.00 56.59  ? 83  VAL A CB    1 
ATOM   634   C CG1   . VAL A 1 83  ? -26.278 -20.866 -7.495   1.00 57.74  ? 83  VAL A CG1   1 
ATOM   635   C CG2   . VAL A 1 83  ? -26.861 -22.602 -5.772   1.00 61.97  ? 83  VAL A CG2   1 
ATOM   636   N N     . SER A 1 84  ? -28.976 -20.087 -3.749   1.00 55.75  ? 84  SER A N     1 
ATOM   637   C CA    . SER A 1 84  ? -29.822 -20.447 -2.627   1.00 64.57  ? 84  SER A CA    1 
ATOM   638   C C     . SER A 1 84  ? -30.401 -21.833 -2.881   1.00 68.21  ? 84  SER A C     1 
ATOM   639   O O     . SER A 1 84  ? -30.229 -22.720 -2.049   1.00 64.97  ? 84  SER A O     1 
ATOM   640   C CB    . SER A 1 84  ? -30.881 -19.410 -2.357   1.00 61.77  ? 84  SER A CB    1 
ATOM   641   O OG    . SER A 1 84  ? -30.261 -18.166 -2.075   1.00 64.75  ? 84  SER A OG    1 
ATOM   642   N N     . ARG A 1 85  ? -31.066 -21.990 -4.032   1.00 66.68  ? 85  ARG A N     1 
ATOM   643   C CA    . ARG A 1 85  ? -31.485 -23.287 -4.537   1.00 66.64  ? 85  ARG A CA    1 
ATOM   644   C C     . ARG A 1 85  ? -31.072 -23.459 -5.999   1.00 75.62  ? 85  ARG A C     1 
ATOM   645   O O     . ARG A 1 85  ? -30.939 -24.599 -6.457   1.00 74.58  ? 85  ARG A O     1 
ATOM   646   C CB    . ARG A 1 85  ? -32.997 -23.450 -4.368   1.00 63.41  ? 85  ARG A CB    1 
ATOM   647   C CG    . ARG A 1 85  ? -33.413 -23.666 -2.921   1.00 57.22  ? 85  ARG A CG    1 
ATOM   648   C CD    . ARG A 1 85  ? -34.911 -23.780 -2.797   1.00 57.70  ? 85  ARG A CD    1 
ATOM   649   N NE    . ARG A 1 85  ? -35.446 -24.931 -3.498   1.00 65.26  ? 85  ARG A NE    1 
ATOM   650   C CZ    . ARG A 1 85  ? -35.475 -26.184 -3.043   1.00 65.95  ? 85  ARG A CZ    1 
ATOM   651   N NH1   . ARG A 1 85  ? -35.009 -26.519 -1.847   1.00 59.51  ? 85  ARG A NH1   1 
ATOM   652   N NH2   . ARG A 1 85  ? -35.983 -27.113 -3.829   1.00 68.86  ? 85  ARG A NH2   1 
ATOM   653   N N     . GLY A 1 86  ? -30.911 -22.330 -6.716   1.00 77.33  ? 86  GLY A N     1 
ATOM   654   C CA    . GLY A 1 86  ? -30.317 -22.307 -8.046   1.00 77.11  ? 86  GLY A CA    1 
ATOM   655   C C     . GLY A 1 86  ? -31.306 -22.734 -9.129   1.00 74.59  ? 86  GLY A C     1 
ATOM   656   O O     . GLY A 1 86  ? -30.889 -23.234 -10.169  1.00 72.21  ? 86  GLY A O     1 
ATOM   657   N N     . LYS A 1 87  ? -32.607 -22.521 -8.854   1.00 76.31  ? 87  LYS A N     1 
ATOM   658   C CA    . LYS A 1 87  ? -33.711 -22.804 -9.764   1.00 67.34  ? 87  LYS A CA    1 
ATOM   659   C C     . LYS A 1 87  ? -34.122 -21.531 -10.529  1.00 63.05  ? 87  LYS A C     1 
ATOM   660   O O     . LYS A 1 87  ? -35.311 -21.279 -10.758  1.00 57.93  ? 87  LYS A O     1 
ATOM   661   C CB    . LYS A 1 87  ? -34.849 -23.411 -8.937   1.00 72.07  ? 87  LYS A CB    1 
ATOM   662   C CG    . LYS A 1 87  ? -34.504 -24.702 -8.191   1.00 74.30  ? 87  LYS A CG    1 
ATOM   663   C CD    . LYS A 1 87  ? -34.798 -25.977 -8.978   1.00 79.71  ? 87  LYS A CD    1 
ATOM   664   C CE    . LYS A 1 87  ? -34.587 -27.268 -8.209   1.00 79.30  ? 87  LYS A CE    1 
ATOM   665   N NZ    . LYS A 1 87  ? -33.206 -27.787 -8.368   1.00 86.74  ? 87  LYS A NZ    1 
ATOM   666   N N     . ASN A 1 88  ? -33.095 -20.778 -10.971  1.00 63.76  ? 88  ASN A N     1 
ATOM   667   C CA    . ASN A 1 88  ? -33.207 -19.488 -11.638  1.00 66.09  ? 88  ASN A CA    1 
ATOM   668   C C     . ASN A 1 88  ? -33.278 -19.717 -13.151  1.00 71.79  ? 88  ASN A C     1 
ATOM   669   O O     . ASN A 1 88  ? -32.337 -19.415 -13.891  1.00 59.24  ? 88  ASN A O     1 
ATOM   670   C CB    . ASN A 1 88  ? -32.041 -18.553 -11.263  1.00 61.52  ? 88  ASN A CB    1 
ATOM   671   C CG    . ASN A 1 88  ? -32.349 -17.064 -11.377  1.00 64.83  ? 88  ASN A CG    1 
ATOM   672   O OD1   . ASN A 1 88  ? -33.502 -16.656 -11.514  1.00 61.68  ? 88  ASN A OD1   1 
ATOM   673   N ND2   . ASN A 1 88  ? -31.325 -16.228 -11.307  1.00 64.97  ? 88  ASN A ND2   1 
ATOM   674   N N     . PHE A 1 89  ? -34.426 -20.225 -13.605  1.00 79.64  ? 89  PHE A N     1 
ATOM   675   C CA    . PHE A 1 89  ? -34.596 -20.629 -14.993  1.00 86.91  ? 89  PHE A CA    1 
ATOM   676   C C     . PHE A 1 89  ? -34.763 -19.372 -15.870  1.00 89.72  ? 89  PHE A C     1 
ATOM   677   O O     . PHE A 1 89  ? -35.397 -18.391 -15.455  1.00 75.63  ? 89  PHE A O     1 
ATOM   678   C CB    . PHE A 1 89  ? -35.719 -21.679 -15.038  1.00 86.54  ? 89  PHE A CB    1 
ATOM   679   C CG    . PHE A 1 89  ? -35.470 -22.936 -14.230  1.00 99.69  ? 89  PHE A CG    1 
ATOM   680   C CD1   . PHE A 1 89  ? -34.184 -23.420 -14.009  1.00 111.46 ? 89  PHE A CD1   1 
ATOM   681   C CD2   . PHE A 1 89  ? -36.527 -23.636 -13.664  1.00 103.12 ? 89  PHE A CD2   1 
ATOM   682   C CE1   . PHE A 1 89  ? -33.972 -24.574 -13.265  1.00 114.21 ? 89  PHE A CE1   1 
ATOM   683   C CE2   . PHE A 1 89  ? -36.314 -24.786 -12.917  1.00 96.41  ? 89  PHE A CE2   1 
ATOM   684   C CZ    . PHE A 1 89  ? -35.038 -25.255 -12.718  1.00 102.70 ? 89  PHE A CZ    1 
ATOM   685   N N     . ALA A 1 90  ? -34.123 -19.403 -17.063  1.00 91.05  ? 90  ALA A N     1 
ATOM   686   C CA    . ALA A 1 90  ? -34.077 -18.323 -18.058  1.00 82.42  ? 90  ALA A CA    1 
ATOM   687   C C     . ALA A 1 90  ? -33.019 -17.266 -17.721  1.00 76.86  ? 90  ALA A C     1 
ATOM   688   O O     . ALA A 1 90  ? -32.772 -16.352 -18.524  1.00 56.43  ? 90  ALA A O     1 
ATOM   689   C CB    . ALA A 1 90  ? -35.425 -17.673 -18.249  1.00 81.44  ? 90  ALA A CB    1 
ATOM   690   N N     . TYR A 1 91  ? -32.379 -17.433 -16.551  1.00 73.51  ? 91  TYR A N     1 
ATOM   691   C CA    . TYR A 1 91  ? -31.356 -16.523 -16.066  1.00 69.68  ? 91  TYR A CA    1 
ATOM   692   C C     . TYR A 1 91  ? -29.993 -17.222 -15.950  1.00 59.47  ? 91  TYR A C     1 
ATOM   693   O O     . TYR A 1 91  ? -28.994 -16.564 -15.707  1.00 59.13  ? 91  TYR A O     1 
ATOM   694   C CB    . TYR A 1 91  ? -31.882 -15.846 -14.792  1.00 69.55  ? 91  TYR A CB    1 
ATOM   695   C CG    . TYR A 1 91  ? -33.108 -14.996 -15.048  1.00 74.19  ? 91  TYR A CG    1 
ATOM   696   C CD1   . TYR A 1 91  ? -33.049 -13.919 -15.919  1.00 78.76  ? 91  TYR A CD1   1 
ATOM   697   C CD2   . TYR A 1 91  ? -34.343 -15.289 -14.485  1.00 64.98  ? 91  TYR A CD2   1 
ATOM   698   C CE1   . TYR A 1 91  ? -34.168 -13.153 -16.209  1.00 77.75  ? 91  TYR A CE1   1 
ATOM   699   C CE2   . TYR A 1 91  ? -35.465 -14.509 -14.737  1.00 62.49  ? 91  TYR A CE2   1 
ATOM   700   C CZ    . TYR A 1 91  ? -35.376 -13.430 -15.598  1.00 66.19  ? 91  TYR A CZ    1 
ATOM   701   O OH    . TYR A 1 91  ? -36.448 -12.622 -15.886  1.00 65.33  ? 91  TYR A OH    1 
ATOM   702   N N     . GLY A 1 92  ? -29.910 -18.529 -16.230  1.00 66.12  ? 92  GLY A N     1 
ATOM   703   C CA    . GLY A 1 92  ? -28.659 -19.265 -16.084  1.00 66.41  ? 92  GLY A CA    1 
ATOM   704   C C     . GLY A 1 92  ? -28.763 -20.527 -15.211  1.00 69.25  ? 92  GLY A C     1 
ATOM   705   O O     . GLY A 1 92  ? -27.806 -21.307 -15.134  1.00 64.10  ? 92  GLY A O     1 
ATOM   706   N N     . GLY A 1 93  ? -29.925 -20.745 -14.570  1.00 72.71  ? 93  GLY A N     1 
ATOM   707   C CA    . GLY A 1 93  ? -30.079 -21.792 -13.568  1.00 68.04  ? 93  GLY A CA    1 
ATOM   708   C C     . GLY A 1 93  ? -29.132 -21.575 -12.385  1.00 65.32  ? 93  GLY A C     1 
ATOM   709   O O     . GLY A 1 93  ? -29.226 -20.582 -11.666  1.00 70.16  ? 93  GLY A O     1 
ATOM   710   N N     . ALA A 1 94  ? -28.200 -22.507 -12.210  1.00 62.44  ? 94  ALA A N     1 
ATOM   711   C CA    . ALA A 1 94  ? -27.282 -22.472 -11.090  1.00 65.76  ? 94  ALA A CA    1 
ATOM   712   C C     . ALA A 1 94  ? -25.883 -22.104 -11.580  1.00 67.49  ? 94  ALA A C     1 
ATOM   713   O O     . ALA A 1 94  ? -24.943 -22.069 -10.790  1.00 72.09  ? 94  ALA A O     1 
ATOM   714   C CB    . ALA A 1 94  ? -27.298 -23.817 -10.392  1.00 63.16  ? 94  ALA A CB    1 
ATOM   715   N N     . ALA A 1 95  ? -25.739 -21.830 -12.884  1.00 72.02  ? 95  ALA A N     1 
ATOM   716   C CA    . ALA A 1 95  ? -24.416 -21.786 -13.498  1.00 78.11  ? 95  ALA A CA    1 
ATOM   717   C C     . ALA A 1 95  ? -23.744 -20.426 -13.257  1.00 71.28  ? 95  ALA A C     1 
ATOM   718   O O     . ALA A 1 95  ? -24.428 -19.411 -13.159  1.00 71.89  ? 95  ALA A O     1 
ATOM   719   C CB    . ALA A 1 95  ? -24.531 -22.127 -14.971  1.00 77.14  ? 95  ALA A CB    1 
ATOM   720   N N     . PRO A 1 96  ? -22.394 -20.360 -13.158  1.00 65.20  ? 96  PRO A N     1 
ATOM   721   C CA    . PRO A 1 96  ? -21.668 -19.094 -13.024  1.00 73.96  ? 96  PRO A CA    1 
ATOM   722   C C     . PRO A 1 96  ? -21.285 -18.414 -14.345  1.00 84.77  ? 96  PRO A C     1 
ATOM   723   O O     . PRO A 1 96  ? -21.026 -19.095 -15.336  1.00 105.48 ? 96  PRO A O     1 
ATOM   724   C CB    . PRO A 1 96  ? -20.393 -19.592 -12.326  1.00 70.00  ? 96  PRO A CB    1 
ATOM   725   C CG    . PRO A 1 96  ? -20.096 -20.893 -13.023  1.00 66.54  ? 96  PRO A CG    1 
ATOM   726   C CD    . PRO A 1 96  ? -21.473 -21.506 -13.191  1.00 69.30  ? 96  PRO A CD    1 
ATOM   727   N N     . VAL A 1 97  ? -21.205 -17.072 -14.349  1.00 71.17  ? 97  VAL A N     1 
ATOM   728   C CA    . VAL A 1 97  ? -20.763 -16.310 -15.514  1.00 69.14  ? 97  VAL A CA    1 
ATOM   729   C C     . VAL A 1 97  ? -19.371 -16.754 -15.967  1.00 64.57  ? 97  VAL A C     1 
ATOM   730   O O     . VAL A 1 97  ? -19.145 -17.125 -17.126  1.00 53.23  ? 97  VAL A O     1 
ATOM   731   C CB    . VAL A 1 97  ? -20.743 -14.807 -15.202  1.00 76.30  ? 97  VAL A CB    1 
ATOM   732   C CG1   . VAL A 1 97  ? -19.967 -14.044 -16.264  1.00 82.26  ? 97  VAL A CG1   1 
ATOM   733   C CG2   . VAL A 1 97  ? -22.151 -14.234 -15.011  1.00 80.87  ? 97  VAL A CG2   1 
ATOM   734   N N     . MET A 1 98  ? -18.418 -16.684 -15.040  1.00 67.25  ? 98  MET A N     1 
ATOM   735   C CA    . MET A 1 98  ? -17.080 -17.150 -15.346  1.00 77.77  ? 98  MET A CA    1 
ATOM   736   C C     . MET A 1 98  ? -17.037 -18.666 -15.138  1.00 79.80  ? 98  MET A C     1 
ATOM   737   O O     . MET A 1 98  ? -17.682 -19.192 -14.226  1.00 72.80  ? 98  MET A O     1 
ATOM   738   C CB    . MET A 1 98  ? -16.052 -16.437 -14.466  1.00 78.60  ? 98  MET A CB    1 
ATOM   739   C CG    . MET A 1 98  ? -14.621 -16.550 -14.972  1.00 76.21  ? 98  MET A CG    1 
ATOM   740   S SD    . MET A 1 98  ? -13.401 -15.785 -13.839  1.00 77.69  ? 98  MET A SD    1 
ATOM   741   C CE    . MET A 1 98  ? -13.541 -16.855 -12.403  1.00 67.67  ? 98  MET A CE    1 
ATOM   742   N N     . SER A 1 99  ? -16.328 -19.353 -16.051  1.00 75.07  ? 99  SER A N     1 
ATOM   743   C CA    . SER A 1 99  ? -15.979 -20.763 -15.915  1.00 70.34  ? 99  SER A CA    1 
ATOM   744   C C     . SER A 1 99  ? -14.983 -20.930 -14.779  1.00 58.94  ? 99  SER A C     1 
ATOM   745   O O     . SER A 1 99  ? -14.227 -20.021 -14.468  1.00 66.05  ? 99  SER A O     1 
ATOM   746   C CB    . SER A 1 99  ? -15.384 -21.330 -17.198  1.00 72.59  ? 99  SER A CB    1 
ATOM   747   O OG    . SER A 1 99  ? -16.382 -21.586 -18.179  1.00 74.58  ? 99  SER A OG    1 
ATOM   748   N N     . GLY A 1 100 ? -14.968 -22.112 -14.179  1.00 63.01  ? 100 GLY A N     1 
ATOM   749   C CA    . GLY A 1 100 ? -13.950 -22.436 -13.193  1.00 63.04  ? 100 GLY A CA    1 
ATOM   750   C C     . GLY A 1 100 ? -14.461 -22.212 -11.779  1.00 57.19  ? 100 GLY A C     1 
ATOM   751   O O     . GLY A 1 100 ? -13.798 -22.525 -10.803  1.00 48.82  ? 100 GLY A O     1 
ATOM   752   N N     . THR A 1 101 ? -15.685 -21.707 -11.682  1.00 63.16  ? 101 THR A N     1 
ATOM   753   C CA    . THR A 1 101 ? -16.174 -21.213 -10.416  1.00 63.72  ? 101 THR A CA    1 
ATOM   754   C C     . THR A 1 101 ? -16.704 -22.395 -9.620   1.00 61.01  ? 101 THR A C     1 
ATOM   755   O O     . THR A 1 101 ? -17.422 -23.208 -10.184  1.00 78.16  ? 101 THR A O     1 
ATOM   756   C CB    . THR A 1 101 ? -17.208 -20.125 -10.696  1.00 68.66  ? 101 THR A CB    1 
ATOM   757   O OG1   . THR A 1 101 ? -16.611 -19.198 -11.605  1.00 66.33  ? 101 THR A OG1   1 
ATOM   758   C CG2   . THR A 1 101 ? -17.652 -19.406 -9.446   1.00 76.41  ? 101 THR A CG2   1 
ATOM   759   N N     . VAL A 1 102 ? -16.323 -22.495 -8.337   1.00 63.52  ? 102 VAL A N     1 
ATOM   760   C CA    . VAL A 1 102 ? -16.919 -23.449 -7.406   1.00 59.07  ? 102 VAL A CA    1 
ATOM   761   C C     . VAL A 1 102 ? -18.280 -22.906 -6.965   1.00 58.49  ? 102 VAL A C     1 
ATOM   762   O O     . VAL A 1 102 ? -18.358 -21.787 -6.467   1.00 53.78  ? 102 VAL A O     1 
ATOM   763   C CB    . VAL A 1 102 ? -16.039 -23.697 -6.167   1.00 60.67  ? 102 VAL A CB    1 
ATOM   764   C CG1   . VAL A 1 102 ? -16.543 -24.892 -5.369   1.00 62.11  ? 102 VAL A CG1   1 
ATOM   765   C CG2   . VAL A 1 102 ? -14.563 -23.862 -6.507   1.00 61.13  ? 102 VAL A CG2   1 
ATOM   766   N N     . VAL A 1 103 ? -19.345 -23.691 -7.188   1.00 53.26  ? 103 VAL A N     1 
ATOM   767   C CA    . VAL A 1 103 ? -20.690 -23.331 -6.777   1.00 53.07  ? 103 VAL A CA    1 
ATOM   768   C C     . VAL A 1 103 ? -20.866 -23.604 -5.283   1.00 57.99  ? 103 VAL A C     1 
ATOM   769   O O     . VAL A 1 103 ? -20.672 -24.725 -4.827   1.00 51.35  ? 103 VAL A O     1 
ATOM   770   C CB    . VAL A 1 103 ? -21.748 -24.087 -7.593   1.00 53.02  ? 103 VAL A CB    1 
ATOM   771   C CG1   . VAL A 1 103 ? -23.158 -23.851 -7.058   1.00 58.20  ? 103 VAL A CG1   1 
ATOM   772   C CG2   . VAL A 1 103 ? -21.680 -23.711 -9.055   1.00 48.91  ? 103 VAL A CG2   1 
ATOM   773   N N     . LEU A 1 104 ? -21.235 -22.551 -4.536   1.00 53.37  ? 104 LEU A N     1 
ATOM   774   C CA    . LEU A 1 104 ? -21.595 -22.672 -3.136   1.00 48.39  ? 104 LEU A CA    1 
ATOM   775   C C     . LEU A 1 104 ? -23.105 -22.878 -3.071   1.00 48.57  ? 104 LEU A C     1 
ATOM   776   O O     . LEU A 1 104 ? -23.866 -21.967 -3.348   1.00 49.41  ? 104 LEU A O     1 
ATOM   777   C CB    . LEU A 1 104 ? -21.148 -21.397 -2.427   1.00 48.90  ? 104 LEU A CB    1 
ATOM   778   C CG    . LEU A 1 104 ? -21.538 -21.231 -0.959   1.00 48.46  ? 104 LEU A CG    1 
ATOM   779   C CD1   . LEU A 1 104 ? -20.830 -22.236 -0.074   1.00 48.99  ? 104 LEU A CD1   1 
ATOM   780   C CD2   . LEU A 1 104 ? -21.209 -19.817 -0.492   1.00 52.68  ? 104 LEU A CD2   1 
ATOM   781   N N     . ASP A 1 105 ? -23.519 -24.103 -2.763   1.00 46.73  ? 105 ASP A N     1 
ATOM   782   C CA    . ASP A 1 105 ? -24.906 -24.506 -2.876   1.00 47.64  ? 105 ASP A CA    1 
ATOM   783   C C     . ASP A 1 105 ? -25.507 -24.491 -1.486   1.00 47.33  ? 105 ASP A C     1 
ATOM   784   O O     . ASP A 1 105 ? -24.964 -25.123 -0.583   1.00 46.08  ? 105 ASP A O     1 
ATOM   785   C CB    . ASP A 1 105 ? -25.017 -25.922 -3.444   1.00 48.68  ? 105 ASP A CB    1 
ATOM   786   C CG    . ASP A 1 105 ? -26.433 -26.367 -3.762   1.00 54.45  ? 105 ASP A CG    1 
ATOM   787   O OD1   . ASP A 1 105 ? -27.375 -25.669 -3.363   1.00 60.97  ? 105 ASP A OD1   1 
ATOM   788   O OD2   . ASP A 1 105 ? -26.580 -27.397 -4.438   1.00 61.65  ? 105 ASP A OD2   1 
ATOM   789   N N     . MET A 1 106 ? -26.634 -23.798 -1.321   1.00 45.56  ? 106 MET A N     1 
ATOM   790   C CA    . MET A 1 106 ? -27.119 -23.590 0.026    1.00 47.04  ? 106 MET A CA    1 
ATOM   791   C C     . MET A 1 106 ? -28.477 -24.248 0.236    1.00 51.93  ? 106 MET A C     1 
ATOM   792   O O     . MET A 1 106 ? -29.138 -23.981 1.237    1.00 54.62  ? 106 MET A O     1 
ATOM   793   C CB    . MET A 1 106 ? -27.107 -22.103 0.345    1.00 47.12  ? 106 MET A CB    1 
ATOM   794   C CG    . MET A 1 106 ? -25.677 -21.594 0.486    1.00 51.48  ? 106 MET A CG    1 
ATOM   795   S SD    . MET A 1 106 ? -25.625 -20.079 1.403    1.00 60.16  ? 106 MET A SD    1 
ATOM   796   C CE    . MET A 1 106 ? -26.209 -19.041 0.068    1.00 75.66  ? 106 MET A CE    1 
ATOM   797   N N     . ASN A 1 107 ? -28.783 -25.226 -0.624   1.00 50.79  ? 107 ASN A N     1 
ATOM   798   C CA    . ASN A 1 107 ? -29.980 -26.044 -0.507   1.00 58.21  ? 107 ASN A CA    1 
ATOM   799   C C     . ASN A 1 107 ? -30.157 -26.587 0.903    1.00 50.08  ? 107 ASN A C     1 
ATOM   800   O O     . ASN A 1 107 ? -31.261 -26.611 1.419    1.00 51.45  ? 107 ASN A O     1 
ATOM   801   C CB    . ASN A 1 107 ? -29.965 -27.220 -1.487   1.00 60.90  ? 107 ASN A CB    1 
ATOM   802   C CG    . ASN A 1 107 ? -30.471 -26.779 -2.838   1.00 80.03  ? 107 ASN A CG    1 
ATOM   803   O OD1   . ASN A 1 107 ? -29.707 -26.290 -3.677   1.00 77.18  ? 107 ASN A OD1   1 
ATOM   804   N ND2   . ASN A 1 107 ? -31.781 -26.872 -3.015   1.00 96.41  ? 107 ASN A ND2   1 
ATOM   805   N N     . ARG A 1 108 ? -29.084 -27.082 1.505    1.00 47.13  ? 108 ARG A N     1 
ATOM   806   C CA    . ARG A 1 108 ? -29.250 -27.855 2.723    1.00 50.68  ? 108 ARG A CA    1 
ATOM   807   C C     . ARG A 1 108 ? -29.709 -26.934 3.851    1.00 48.90  ? 108 ARG A C     1 
ATOM   808   O O     . ARG A 1 108 ? -30.352 -27.394 4.777    1.00 48.89  ? 108 ARG A O     1 
ATOM   809   C CB    . ARG A 1 108 ? -27.961 -28.608 3.059    1.00 53.52  ? 108 ARG A CB    1 
ATOM   810   C CG    . ARG A 1 108 ? -27.543 -29.644 2.015    1.00 54.28  ? 108 ARG A CG    1 
ATOM   811   C CD    . ARG A 1 108 ? -26.193 -30.258 2.361    1.00 56.26  ? 108 ARG A CD    1 
ATOM   812   N NE    . ARG A 1 108 ? -26.248 -30.951 3.654    1.00 59.54  ? 108 ARG A NE    1 
ATOM   813   C CZ    . ARG A 1 108 ? -25.356 -30.824 4.632    1.00 55.85  ? 108 ARG A CZ    1 
ATOM   814   N NH1   . ARG A 1 108 ? -24.205 -30.215 4.423    1.00 53.47  ? 108 ARG A NH1   1 
ATOM   815   N NH2   . ARG A 1 108 ? -25.579 -31.387 5.805    1.00 57.21  ? 108 ARG A NH2   1 
ATOM   816   N N     . MET A 1 109 ? -29.375 -25.638 3.752    1.00 51.59  ? 109 MET A N     1 
ATOM   817   C CA    . MET A 1 109 ? -29.754 -24.626 4.731    1.00 44.55  ? 109 MET A CA    1 
ATOM   818   C C     . MET A 1 109 ? -31.181 -24.186 4.432    1.00 43.78  ? 109 MET A C     1 
ATOM   819   O O     . MET A 1 109 ? -31.408 -23.150 3.804    1.00 45.79  ? 109 MET A O     1 
ATOM   820   C CB    . MET A 1 109 ? -28.798 -23.423 4.682    1.00 47.38  ? 109 MET A CB    1 
ATOM   821   C CG    . MET A 1 109 ? -27.410 -23.720 5.277    1.00 47.83  ? 109 MET A CG    1 
ATOM   822   S SD    . MET A 1 109 ? -26.141 -22.456 4.908    1.00 50.26  ? 109 MET A SD    1 
ATOM   823   C CE    . MET A 1 109 ? -26.714 -21.186 6.042    1.00 58.07  ? 109 MET A CE    1 
ATOM   824   N N     . ASN A 1 110 ? -32.136 -24.988 4.920    1.00 46.46  ? 110 ASN A N     1 
ATOM   825   C CA    . ASN A 1 110 ? -33.526 -24.932 4.497    1.00 47.17  ? 110 ASN A CA    1 
ATOM   826   C C     . ASN A 1 110 ? -34.464 -24.902 5.696    1.00 39.54  ? 110 ASN A C     1 
ATOM   827   O O     . ASN A 1 110 ? -35.595 -25.374 5.609    1.00 39.28  ? 110 ASN A O     1 
ATOM   828   C CB    . ASN A 1 110 ? -33.898 -26.152 3.641    1.00 50.13  ? 110 ASN A CB    1 
ATOM   829   C CG    . ASN A 1 110 ? -33.792 -27.469 4.393    1.00 48.57  ? 110 ASN A CG    1 
ATOM   830   O OD1   . ASN A 1 110 ? -33.230 -27.541 5.479    1.00 48.23  ? 110 ASN A OD1   1 
ATOM   831   N ND2   . ASN A 1 110 ? -34.350 -28.525 3.835    1.00 50.44  ? 110 ASN A ND2   1 
ATOM   832   N N     . ARG A 1 111 ? -33.988 -24.404 6.825    1.00 44.20  ? 111 ARG A N     1 
ATOM   833   C CA    . ARG A 1 111 ? -34.839 -24.328 7.997    1.00 50.18  ? 111 ARG A CA    1 
ATOM   834   C C     . ARG A 1 111 ? -35.724 -23.075 7.884    1.00 53.47  ? 111 ARG A C     1 
ATOM   835   O O     . ARG A 1 111 ? -35.299 -22.016 7.421    1.00 50.40  ? 111 ARG A O     1 
ATOM   836   C CB    . ARG A 1 111 ? -33.947 -24.397 9.234    1.00 55.60  ? 111 ARG A CB    1 
ATOM   837   C CG    . ARG A 1 111 ? -34.438 -25.369 10.301   1.00 76.62  ? 111 ARG A CG    1 
ATOM   838   C CD    . ARG A 1 111 ? -33.713 -25.188 11.627   1.00 83.69  ? 111 ARG A CD    1 
ATOM   839   N NE    . ARG A 1 111 ? -32.307 -24.892 11.381   1.00 84.23  ? 111 ARG A NE    1 
ATOM   840   C CZ    . ARG A 1 111 ? -31.541 -24.154 12.170   1.00 92.75  ? 111 ARG A CZ    1 
ATOM   841   N NH1   . ARG A 1 111 ? -31.940 -23.865 13.399   1.00 84.82  ? 111 ARG A NH1   1 
ATOM   842   N NH2   . ARG A 1 111 ? -30.369 -23.730 11.722   1.00 95.79  ? 111 ARG A NH2   1 
ATOM   843   N N     . ILE A 1 112 ? -36.997 -23.208 8.256    1.00 48.22  ? 112 ILE A N     1 
ATOM   844   C CA    . ILE A 1 112 ? -37.849 -22.052 8.478    1.00 39.38  ? 112 ILE A CA    1 
ATOM   845   C C     . ILE A 1 112 ? -37.745 -21.654 9.951    1.00 38.18  ? 112 ILE A C     1 
ATOM   846   O O     . ILE A 1 112 ? -38.292 -22.326 10.802   1.00 43.00  ? 112 ILE A O     1 
ATOM   847   C CB    . ILE A 1 112 ? -39.293 -22.393 8.082    1.00 37.34  ? 112 ILE A CB    1 
ATOM   848   C CG1   . ILE A 1 112 ? -39.387 -22.841 6.613    1.00 42.18  ? 112 ILE A CG1   1 
ATOM   849   C CG2   . ILE A 1 112 ? -40.222 -21.234 8.408    1.00 39.75  ? 112 ILE A CG2   1 
ATOM   850   C CD1   . ILE A 1 112 ? -40.756 -23.423 6.209    1.00 36.60  ? 112 ILE A CD1   1 
ATOM   851   N N     . LEU A 1 113 ? -37.073 -20.546 10.248   1.00 40.11  ? 113 LEU A N     1 
ATOM   852   C CA    . LEU A 1 113 ? -36.689 -20.212 11.609   1.00 39.46  ? 113 LEU A CA    1 
ATOM   853   C C     . LEU A 1 113 ? -37.878 -19.650 12.368   1.00 39.12  ? 113 LEU A C     1 
ATOM   854   O O     . LEU A 1 113 ? -38.056 -19.958 13.536   1.00 46.39  ? 113 LEU A O     1 
ATOM   855   C CB    . LEU A 1 113 ? -35.523 -19.229 11.558   1.00 44.32  ? 113 LEU A CB    1 
ATOM   856   C CG    . LEU A 1 113 ? -34.203 -19.810 11.024   1.00 45.90  ? 113 LEU A CG    1 
ATOM   857   C CD1   . LEU A 1 113 ? -33.231 -18.723 10.630   1.00 45.37  ? 113 LEU A CD1   1 
ATOM   858   C CD2   . LEU A 1 113 ? -33.533 -20.687 12.058   1.00 46.88  ? 113 LEU A CD2   1 
ATOM   859   N N     . GLU A 1 114 ? -38.731 -18.893 11.684   1.00 40.67  ? 114 GLU A N     1 
ATOM   860   C CA    . GLU A 1 114 ? -39.936 -18.358 12.294   1.00 38.87  ? 114 GLU A CA    1 
ATOM   861   C C     . GLU A 1 114 ? -40.958 -18.002 11.219   1.00 39.85  ? 114 GLU A C     1 
ATOM   862   O O     . GLU A 1 114 ? -40.610 -17.566 10.120   1.00 39.61  ? 114 GLU A O     1 
ATOM   863   C CB    . GLU A 1 114 ? -39.637 -17.122 13.141   1.00 43.56  ? 114 GLU A CB    1 
ATOM   864   C CG    . GLU A 1 114 ? -40.794 -16.745 14.056   1.00 56.08  ? 114 GLU A CG    1 
ATOM   865   C CD    . GLU A 1 114 ? -40.621 -15.500 14.925   1.00 65.30  ? 114 GLU A CD    1 
ATOM   866   O OE1   . GLU A 1 114 ? -39.543 -14.799 14.817   1.00 52.99  ? 114 GLU A OE1   1 
ATOM   867   O OE2   . GLU A 1 114 ? -41.585 -15.220 15.706   1.00 58.02  ? 114 GLU A OE2   1 
ATOM   868   N N     . VAL A 1 115 ? -42.227 -18.249 11.551   1.00 38.68  ? 115 VAL A N     1 
ATOM   869   C CA    . VAL A 1 115 ? -43.356 -17.687 10.843   1.00 39.21  ? 115 VAL A CA    1 
ATOM   870   C C     . VAL A 1 115 ? -44.241 -17.120 11.921   1.00 38.52  ? 115 VAL A C     1 
ATOM   871   O O     . VAL A 1 115 ? -44.632 -17.853 12.806   1.00 41.77  ? 115 VAL A O     1 
ATOM   872   C CB    . VAL A 1 115 ? -44.144 -18.701 10.002   1.00 44.57  ? 115 VAL A CB    1 
ATOM   873   C CG1   . VAL A 1 115 ? -45.422 -18.096 9.456    1.00 43.94  ? 115 VAL A CG1   1 
ATOM   874   C CG2   . VAL A 1 115 ? -43.290 -19.267 8.882    1.00 50.48  ? 115 VAL A CG2   1 
ATOM   875   N N     . ASN A 1 116 ? -44.482 -15.815 11.864   1.00 41.06  ? 116 ASN A N     1 
ATOM   876   C CA    . ASN A 1 116 ? -45.189 -15.139 12.924   1.00 38.60  ? 116 ASN A CA    1 
ATOM   877   C C     . ASN A 1 116 ? -46.523 -14.671 12.359   1.00 40.64  ? 116 ASN A C     1 
ATOM   878   O O     . ASN A 1 116 ? -46.544 -13.982 11.351   1.00 43.88  ? 116 ASN A O     1 
ATOM   879   C CB    . ASN A 1 116 ? -44.318 -14.019 13.484   1.00 40.74  ? 116 ASN A CB    1 
ATOM   880   C CG    . ASN A 1 116 ? -44.995 -13.295 14.618   1.00 42.42  ? 116 ASN A CG    1 
ATOM   881   O OD1   . ASN A 1 116 ? -46.174 -12.930 14.526   1.00 45.22  ? 116 ASN A OD1   1 
ATOM   882   N ND2   . ASN A 1 116 ? -44.270 -13.156 15.711   1.00 43.59  ? 116 ASN A ND2   1 
ATOM   883   N N     . GLU A 1 117 ? -47.629 -15.032 13.014   1.00 44.85  ? 117 GLU A N     1 
ATOM   884   C CA    . GLU A 1 117 ? -48.932 -14.717 12.466   1.00 44.83  ? 117 GLU A CA    1 
ATOM   885   C C     . GLU A 1 117 ? -49.367 -13.320 12.908   1.00 40.51  ? 117 GLU A C     1 
ATOM   886   O O     . GLU A 1 117 ? -49.923 -12.604 12.097   1.00 38.93  ? 117 GLU A O     1 
ATOM   887   C CB    . GLU A 1 117 ? -49.942 -15.795 12.857   1.00 48.93  ? 117 GLU A CB    1 
ATOM   888   C CG    . GLU A 1 117 ? -51.359 -15.501 12.362   1.00 49.15  ? 117 GLU A CG    1 
ATOM   889   C CD    . GLU A 1 117 ? -52.338 -16.625 12.662   1.00 49.52  ? 117 GLU A CD    1 
ATOM   890   O OE1   . GLU A 1 117 ? -52.451 -16.990 13.835   1.00 54.15  ? 117 GLU A OE1   1 
ATOM   891   O OE2   . GLU A 1 117 ? -52.970 -17.141 11.727   1.00 46.05  ? 117 GLU A OE2   1 
ATOM   892   N N     . GLU A 1 118 ? -49.163 -12.945 14.178   1.00 38.47  ? 118 GLU A N     1 
ATOM   893   C CA    . GLU A 1 118 ? -49.570 -11.622 14.650   1.00 43.75  ? 118 GLU A CA    1 
ATOM   894   C C     . GLU A 1 118 ? -48.957 -10.486 13.805   1.00 43.54  ? 118 GLU A C     1 
ATOM   895   O O     . GLU A 1 118 ? -49.553 -9.443  13.651   1.00 42.71  ? 118 GLU A O     1 
ATOM   896   C CB    . GLU A 1 118 ? -48.991 -11.300 16.030   1.00 52.32  ? 118 GLU A CB    1 
ATOM   897   C CG    . GLU A 1 118 ? -49.570 -11.993 17.241   1.00 62.12  ? 118 GLU A CG    1 
ATOM   898   C CD    . GLU A 1 118 ? -48.860 -11.562 18.525   1.00 70.79  ? 118 GLU A CD    1 
ATOM   899   O OE1   . GLU A 1 118 ? -47.583 -11.507 18.535   1.00 61.94  ? 118 GLU A OE1   1 
ATOM   900   O OE2   . GLU A 1 118 ? -49.569 -11.269 19.518   1.00 71.57  ? 118 GLU A OE2   1 
ATOM   901   N N     . PHE A 1 119 ? -47.693 -10.641 13.379   1.00 44.61  ? 119 PHE A N     1 
ATOM   902   C CA    . PHE A 1 119 ? -46.918 -9.598  12.737   1.00 40.65  ? 119 PHE A CA    1 
ATOM   903   C C     . PHE A 1 119 ? -46.745 -9.824  11.236   1.00 40.00  ? 119 PHE A C     1 
ATOM   904   O O     . PHE A 1 119 ? -46.127 -9.013  10.568   1.00 39.46  ? 119 PHE A O     1 
ATOM   905   C CB    . PHE A 1 119 ? -45.547 -9.506  13.402   1.00 45.74  ? 119 PHE A CB    1 
ATOM   906   C CG    . PHE A 1 119 ? -45.597 -9.212  14.881   1.00 48.07  ? 119 PHE A CG    1 
ATOM   907   C CD1   . PHE A 1 119 ? -46.454 -8.247  15.388   1.00 48.97  ? 119 PHE A CD1   1 
ATOM   908   C CD2   . PHE A 1 119 ? -44.766 -9.887  15.768   1.00 49.23  ? 119 PHE A CD2   1 
ATOM   909   C CE1   . PHE A 1 119 ? -46.493 -7.976  16.748   1.00 49.24  ? 119 PHE A CE1   1 
ATOM   910   C CE2   . PHE A 1 119 ? -44.814 -9.624  17.128   1.00 50.25  ? 119 PHE A CE2   1 
ATOM   911   C CZ    . PHE A 1 119 ? -45.679 -8.663  17.616   1.00 48.94  ? 119 PHE A CZ    1 
ATOM   912   N N     . GLY A 1 120 ? -47.265 -10.929 10.692   1.00 45.17  ? 120 GLY A N     1 
ATOM   913   C CA    . GLY A 1 120 ? -47.214 -11.180 9.260    1.00 39.66  ? 120 GLY A CA    1 
ATOM   914   C C     . GLY A 1 120 ? -45.783 -11.172 8.715    1.00 41.02  ? 120 GLY A C     1 
ATOM   915   O O     . GLY A 1 120 ? -45.467 -10.369 7.863    1.00 43.46  ? 120 GLY A O     1 
ATOM   916   N N     . TYR A 1 121 ? -44.910 -12.057 9.210    1.00 43.24  ? 121 TYR A N     1 
ATOM   917   C CA    . TYR A 1 121 ? -43.597 -12.229 8.608    1.00 43.64  ? 121 TYR A CA    1 
ATOM   918   C C     . TYR A 1 121 ? -43.102 -13.665 8.730    1.00 40.10  ? 121 TYR A C     1 
ATOM   919   O O     . TYR A 1 121 ? -43.726 -14.482 9.394    1.00 36.01  ? 121 TYR A O     1 
ATOM   920   C CB    . TYR A 1 121 ? -42.586 -11.275 9.241    1.00 45.48  ? 121 TYR A CB    1 
ATOM   921   C CG    . TYR A 1 121 ? -42.125 -11.589 10.643   1.00 40.95  ? 121 TYR A CG    1 
ATOM   922   C CD1   . TYR A 1 121 ? -41.163 -12.557 10.890   1.00 44.77  ? 121 TYR A CD1   1 
ATOM   923   C CD2   . TYR A 1 121 ? -42.566 -10.834 11.712   1.00 39.46  ? 121 TYR A CD2   1 
ATOM   924   C CE1   . TYR A 1 121 ? -40.701 -12.807 12.177   1.00 46.66  ? 121 TYR A CE1   1 
ATOM   925   C CE2   . TYR A 1 121 ? -42.106 -11.061 13.001   1.00 43.62  ? 121 TYR A CE2   1 
ATOM   926   C CZ    . TYR A 1 121 ? -41.184 -12.063 13.243   1.00 41.63  ? 121 TYR A CZ    1 
ATOM   927   O OH    . TYR A 1 121 ? -40.719 -12.260 14.513   1.00 39.22  ? 121 TYR A OH    1 
ATOM   928   N N     . ALA A 1 122 ? -41.958 -13.923 8.078    1.00 41.84  ? 122 ALA A N     1 
ATOM   929   C CA    . ALA A 1 122 ? -41.213 -15.175 8.166    1.00 37.72  ? 122 ALA A CA    1 
ATOM   930   C C     . ALA A 1 122 ? -39.716 -14.881 8.172    1.00 36.61  ? 122 ALA A C     1 
ATOM   931   O O     . ALA A 1 122 ? -39.267 -13.873 7.635    1.00 37.58  ? 122 ALA A O     1 
ATOM   932   C CB    . ALA A 1 122 ? -41.585 -16.073 7.008    1.00 39.36  ? 122 ALA A CB    1 
ATOM   933   N N     . LEU A 1 123 ? -38.952 -15.732 8.855    1.00 44.04  ? 123 LEU A N     1 
ATOM   934   C CA    . LEU A 1 123 ? -37.499 -15.700 8.809    1.00 41.22  ? 123 LEU A CA    1 
ATOM   935   C C     . LEU A 1 123 ? -37.036 -17.044 8.267    1.00 45.56  ? 123 LEU A C     1 
ATOM   936   O O     . LEU A 1 123 ? -37.316 -18.076 8.890    1.00 41.19  ? 123 LEU A O     1 
ATOM   937   C CB    . LEU A 1 123 ? -36.934 -15.469 10.210   1.00 37.69  ? 123 LEU A CB    1 
ATOM   938   C CG    . LEU A 1 123 ? -35.415 -15.345 10.291   1.00 33.60  ? 123 LEU A CG    1 
ATOM   939   C CD1   . LEU A 1 123 ? -34.918 -14.108 9.599    1.00 36.99  ? 123 LEU A CD1   1 
ATOM   940   C CD2   . LEU A 1 123 ? -34.970 -15.286 11.711   1.00 36.93  ? 123 LEU A CD2   1 
ATOM   941   N N     . VAL A 1 124 ? -36.330 -17.000 7.124    1.00 43.91  ? 124 VAL A N     1 
ATOM   942   C CA    . VAL A 1 124 ? -36.029 -18.192 6.353    1.00 42.66  ? 124 VAL A CA    1 
ATOM   943   C C     . VAL A 1 124 ? -34.559 -18.215 5.952    1.00 39.44  ? 124 VAL A C     1 
ATOM   944   O O     . VAL A 1 124 ? -33.949 -17.168 5.755    1.00 38.24  ? 124 VAL A O     1 
ATOM   945   C CB    . VAL A 1 124 ? -36.921 -18.294 5.111    1.00 44.29  ? 124 VAL A CB    1 
ATOM   946   C CG1   . VAL A 1 124 ? -38.385 -18.509 5.483    1.00 48.43  ? 124 VAL A CG1   1 
ATOM   947   C CG2   . VAL A 1 124 ? -36.745 -17.078 4.212    1.00 45.61  ? 124 VAL A CG2   1 
ATOM   948   N N     . GLU A 1 125 ? -34.027 -19.443 5.815    1.00 36.41  ? 125 GLU A N     1 
ATOM   949   C CA    . GLU A 1 125 ? -32.712 -19.685 5.248    1.00 36.05  ? 125 GLU A CA    1 
ATOM   950   C C     . GLU A 1 125 ? -32.851 -19.805 3.735    1.00 31.02  ? 125 GLU A C     1 
ATOM   951   O O     . GLU A 1 125 ? -33.966 -19.897 3.211    1.00 31.98  ? 125 GLU A O     1 
ATOM   952   C CB    . GLU A 1 125 ? -32.087 -20.949 5.834    1.00 38.65  ? 125 GLU A CB    1 
ATOM   953   C CG    . GLU A 1 125 ? -31.911 -20.930 7.335    1.00 40.87  ? 125 GLU A CG    1 
ATOM   954   C CD    . GLU A 1 125 ? -31.054 -22.057 7.902    1.00 45.82  ? 125 GLU A CD    1 
ATOM   955   O OE1   . GLU A 1 125 ? -31.162 -23.223 7.452    1.00 49.98  ? 125 GLU A OE1   1 
ATOM   956   O OE2   . GLU A 1 125 ? -30.300 -21.784 8.825    1.00 51.70  ? 125 GLU A OE2   1 
ATOM   957   N N     . PRO A 1 126 ? -31.739 -19.776 2.980    1.00 31.81  ? 126 PRO A N     1 
ATOM   958   C CA    . PRO A 1 126 ? -31.807 -19.766 1.516    1.00 35.21  ? 126 PRO A CA    1 
ATOM   959   C C     . PRO A 1 126 ? -32.393 -21.021 0.857    1.00 36.59  ? 126 PRO A C     1 
ATOM   960   O O     . PRO A 1 126 ? -32.959 -20.954 -0.239   1.00 38.39  ? 126 PRO A O     1 
ATOM   961   C CB    . PRO A 1 126 ? -30.323 -19.630 1.123    1.00 37.35  ? 126 PRO A CB    1 
ATOM   962   C CG    . PRO A 1 126 ? -29.671 -19.020 2.322    1.00 35.02  ? 126 PRO A CG    1 
ATOM   963   C CD    . PRO A 1 126 ? -30.358 -19.705 3.477    1.00 34.95  ? 126 PRO A CD    1 
ATOM   964   N N     . GLY A 1 127 ? -32.243 -22.171 1.530    1.00 38.17  ? 127 GLY A N     1 
ATOM   965   C CA    . GLY A 1 127 ? -32.737 -23.449 1.034    1.00 40.94  ? 127 GLY A CA    1 
ATOM   966   C C     . GLY A 1 127 ? -34.265 -23.587 0.943    1.00 43.46  ? 127 GLY A C     1 
ATOM   967   O O     . GLY A 1 127 ? -34.750 -24.506 0.275    1.00 47.64  ? 127 GLY A O     1 
ATOM   968   N N     . VAL A 1 128 ? -35.027 -22.723 1.641    1.00 42.61  ? 128 VAL A N     1 
ATOM   969   C CA    . VAL A 1 128 ? -36.482 -22.831 1.707    1.00 35.30  ? 128 VAL A CA    1 
ATOM   970   C C     . VAL A 1 128 ? -37.090 -22.347 0.393    1.00 36.74  ? 128 VAL A C     1 
ATOM   971   O O     . VAL A 1 128 ? -36.846 -21.237 -0.072   1.00 34.67  ? 128 VAL A O     1 
ATOM   972   C CB    . VAL A 1 128 ? -37.070 -22.002 2.855    1.00 33.99  ? 128 VAL A CB    1 
ATOM   973   C CG1   . VAL A 1 128 ? -38.598 -22.077 2.899    1.00 30.82  ? 128 VAL A CG1   1 
ATOM   974   C CG2   . VAL A 1 128 ? -36.438 -22.356 4.186    1.00 38.89  ? 128 VAL A CG2   1 
ATOM   975   N N     . SER A 1 129 ? -37.930 -23.197 -0.171   1.00 38.10  ? 129 SER A N     1 
ATOM   976   C CA    . SER A 1 129 ? -38.612 -22.932 -1.423   1.00 40.50  ? 129 SER A CA    1 
ATOM   977   C C     . SER A 1 129 ? -40.008 -22.400 -1.105   1.00 39.14  ? 129 SER A C     1 
ATOM   978   O O     . SER A 1 129 ? -40.492 -22.593 0.008    1.00 32.69  ? 129 SER A O     1 
ATOM   979   C CB    . SER A 1 129 ? -38.745 -24.229 -2.199   1.00 39.55  ? 129 SER A CB    1 
ATOM   980   O OG    . SER A 1 129 ? -39.609 -25.128 -1.477   1.00 37.91  ? 129 SER A OG    1 
ATOM   981   N N     . TYR A 1 130 ? -40.675 -21.885 -2.144   1.00 37.01  ? 130 TYR A N     1 
ATOM   982   C CA    . TYR A 1 130 ? -42.038 -21.419 -2.058   1.00 39.32  ? 130 TYR A CA    1 
ATOM   983   C C     . TYR A 1 130 ? -42.934 -22.594 -1.682   1.00 41.90  ? 130 TYR A C     1 
ATOM   984   O O     . TYR A 1 130 ? -43.802 -22.434 -0.830   1.00 42.31  ? 130 TYR A O     1 
ATOM   985   C CB    . TYR A 1 130 ? -42.428 -20.686 -3.348   1.00 42.92  ? 130 TYR A CB    1 
ATOM   986   C CG    . TYR A 1 130 ? -41.690 -19.392 -3.651   1.00 46.22  ? 130 TYR A CG    1 
ATOM   987   C CD1   . TYR A 1 130 ? -41.990 -18.212 -2.986   1.00 42.02  ? 130 TYR A CD1   1 
ATOM   988   C CD2   . TYR A 1 130 ? -40.684 -19.333 -4.612   1.00 46.70  ? 130 TYR A CD2   1 
ATOM   989   C CE1   . TYR A 1 130 ? -41.320 -17.025 -3.259   1.00 42.31  ? 130 TYR A CE1   1 
ATOM   990   C CE2   . TYR A 1 130 ? -39.997 -18.154 -4.886   1.00 48.83  ? 130 TYR A CE2   1 
ATOM   991   C CZ    . TYR A 1 130 ? -40.314 -16.987 -4.209   1.00 48.94  ? 130 TYR A CZ    1 
ATOM   992   O OH    . TYR A 1 130 ? -39.653 -15.793 -4.489   1.00 40.44  ? 130 TYR A OH    1 
ATOM   993   N N     . PHE A 1 131 ? -42.674 -23.786 -2.248   1.00 45.49  ? 131 PHE A N     1 
ATOM   994   C CA    . PHE A 1 131 ? -43.462 -24.973 -1.920   1.00 40.14  ? 131 PHE A CA    1 
ATOM   995   C C     . PHE A 1 131 ? -43.352 -25.301 -0.436   1.00 40.67  ? 131 PHE A C     1 
ATOM   996   O O     . PHE A 1 131 ? -44.376 -25.528 0.185    1.00 45.59  ? 131 PHE A O     1 
ATOM   997   C CB    . PHE A 1 131 ? -43.091 -26.190 -2.772   1.00 39.54  ? 131 PHE A CB    1 
ATOM   998   C CG    . PHE A 1 131 ? -43.761 -26.217 -4.120   1.00 37.99  ? 131 PHE A CG    1 
ATOM   999   C CD1   . PHE A 1 131 ? -45.141 -26.271 -4.221   1.00 42.70  ? 131 PHE A CD1   1 
ATOM   1000  C CD2   . PHE A 1 131 ? -43.027 -26.136 -5.283   1.00 39.96  ? 131 PHE A CD2   1 
ATOM   1001  C CE1   . PHE A 1 131 ? -45.774 -26.262 -5.458   1.00 43.23  ? 131 PHE A CE1   1 
ATOM   1002  C CE2   . PHE A 1 131 ? -43.657 -26.094 -6.517   1.00 46.11  ? 131 PHE A CE2   1 
ATOM   1003  C CZ    . PHE A 1 131 ? -45.032 -26.164 -6.606   1.00 46.56  ? 131 PHE A CZ    1 
ATOM   1004  N N     . GLU A 1 132 ? -42.141 -25.281 0.137    1.00 43.35  ? 132 GLU A N     1 
ATOM   1005  C CA    . GLU A 1 132 ? -41.955 -25.642 1.539    1.00 45.76  ? 132 GLU A CA    1 
ATOM   1006  C C     . GLU A 1 132 ? -42.636 -24.624 2.447    1.00 43.59  ? 132 GLU A C     1 
ATOM   1007  O O     . GLU A 1 132 ? -43.259 -24.997 3.420    1.00 43.77  ? 132 GLU A O     1 
ATOM   1008  C CB    . GLU A 1 132 ? -40.469 -25.777 1.891    1.00 50.36  ? 132 GLU A CB    1 
ATOM   1009  C CG    . GLU A 1 132 ? -39.783 -26.915 1.138    1.00 61.46  ? 132 GLU A CG    1 
ATOM   1010  C CD    . GLU A 1 132 ? -38.258 -26.916 1.112    1.00 69.67  ? 132 GLU A CD    1 
ATOM   1011  O OE1   . GLU A 1 132 ? -37.639 -26.032 1.737    1.00 72.08  ? 132 GLU A OE1   1 
ATOM   1012  O OE2   . GLU A 1 132 ? -37.690 -27.825 0.485    1.00 75.38  ? 132 GLU A OE2   1 
ATOM   1013  N N     . LEU A 1 133 ? -42.553 -23.333 2.095    1.00 46.99  ? 133 LEU A N     1 
ATOM   1014  C CA    . LEU A 1 133 ? -43.095 -22.287 2.941    1.00 42.43  ? 133 LEU A CA    1 
ATOM   1015  C C     . LEU A 1 133 ? -44.623 -22.310 2.889    1.00 45.20  ? 133 LEU A C     1 
ATOM   1016  O O     . LEU A 1 133 ? -45.253 -22.127 3.926    1.00 42.62  ? 133 LEU A O     1 
ATOM   1017  C CB    . LEU A 1 133 ? -42.532 -20.931 2.514    1.00 43.40  ? 133 LEU A CB    1 
ATOM   1018  C CG    . LEU A 1 133 ? -42.991 -19.729 3.343    1.00 45.55  ? 133 LEU A CG    1 
ATOM   1019  C CD1   . LEU A 1 133 ? -42.618 -19.895 4.804    1.00 42.35  ? 133 LEU A CD1   1 
ATOM   1020  C CD2   . LEU A 1 133 ? -42.393 -18.440 2.795    1.00 46.64  ? 133 LEU A CD2   1 
ATOM   1021  N N     . TYR A 1 134 ? -45.207 -22.482 1.691    1.00 41.73  ? 134 TYR A N     1 
ATOM   1022  C CA    . TYR A 1 134 ? -46.649 -22.595 1.542    1.00 41.90  ? 134 TYR A CA    1 
ATOM   1023  C C     . TYR A 1 134 ? -47.151 -23.782 2.374    1.00 50.81  ? 134 TYR A C     1 
ATOM   1024  O O     . TYR A 1 134 ? -48.114 -23.653 3.130    1.00 49.04  ? 134 TYR A O     1 
ATOM   1025  C CB    . TYR A 1 134 ? -47.031 -22.724 0.064    1.00 43.91  ? 134 TYR A CB    1 
ATOM   1026  C CG    . TYR A 1 134 ? -48.514 -22.855 -0.202   1.00 45.26  ? 134 TYR A CG    1 
ATOM   1027  C CD1   . TYR A 1 134 ? -49.341 -21.755 -0.209   1.00 42.79  ? 134 TYR A CD1   1 
ATOM   1028  C CD2   . TYR A 1 134 ? -49.098 -24.094 -0.436   1.00 44.21  ? 134 TYR A CD2   1 
ATOM   1029  C CE1   . TYR A 1 134 ? -50.704 -21.880 -0.439   1.00 42.64  ? 134 TYR A CE1   1 
ATOM   1030  C CE2   . TYR A 1 134 ? -50.454 -24.236 -0.663   1.00 39.04  ? 134 TYR A CE2   1 
ATOM   1031  C CZ    . TYR A 1 134 ? -51.268 -23.120 -0.672   1.00 42.55  ? 134 TYR A CZ    1 
ATOM   1032  O OH    . TYR A 1 134 ? -52.634 -23.233 -0.850   1.00 40.87  ? 134 TYR A OH    1 
ATOM   1033  N N     . ASP A 1 135 ? -46.467 -24.931 2.278    1.00 52.56  ? 135 ASP A N     1 
ATOM   1034  C CA    . ASP A 1 135 ? -46.961 -26.163 2.892    1.00 56.02  ? 135 ASP A CA    1 
ATOM   1035  C C     . ASP A 1 135 ? -46.896 -26.050 4.430    1.00 52.40  ? 135 ASP A C     1 
ATOM   1036  O O     . ASP A 1 135 ? -47.807 -26.475 5.141    1.00 49.37  ? 135 ASP A O     1 
ATOM   1037  C CB    . ASP A 1 135 ? -46.244 -27.406 2.326    1.00 53.24  ? 135 ASP A CB    1 
ATOM   1038  C CG    . ASP A 1 135 ? -46.475 -27.780 0.854    1.00 53.07  ? 135 ASP A CG    1 
ATOM   1039  O OD1   . ASP A 1 135 ? -47.472 -27.359 0.234    1.00 55.87  ? 135 ASP A OD1   1 
ATOM   1040  O OD2   . ASP A 1 135 ? -45.622 -28.487 0.311    1.00 59.51  ? 135 ASP A OD2   1 
ATOM   1041  N N     . TYR A 1 136 ? -45.824 -25.447 4.947    1.00 49.05  ? 136 TYR A N     1 
ATOM   1042  C CA    . TYR A 1 136 ? -45.661 -25.204 6.373    1.00 54.04  ? 136 TYR A CA    1 
ATOM   1043  C C     . TYR A 1 136 ? -46.826 -24.344 6.885    1.00 52.04  ? 136 TYR A C     1 
ATOM   1044  O O     . TYR A 1 136 ? -47.406 -24.619 7.941    1.00 53.83  ? 136 TYR A O     1 
ATOM   1045  C CB    . TYR A 1 136 ? -44.259 -24.615 6.648    1.00 51.15  ? 136 TYR A CB    1 
ATOM   1046  C CG    . TYR A 1 136 ? -43.996 -24.255 8.094    1.00 56.62  ? 136 TYR A CG    1 
ATOM   1047  C CD1   . TYR A 1 136 ? -44.604 -23.143 8.665    1.00 59.46  ? 136 TYR A CD1   1 
ATOM   1048  C CD2   . TYR A 1 136 ? -43.153 -25.011 8.903    1.00 57.68  ? 136 TYR A CD2   1 
ATOM   1049  C CE1   . TYR A 1 136 ? -44.397 -22.800 9.991    1.00 56.61  ? 136 TYR A CE1   1 
ATOM   1050  C CE2   . TYR A 1 136 ? -42.928 -24.680 10.232   1.00 55.84  ? 136 TYR A CE2   1 
ATOM   1051  C CZ    . TYR A 1 136 ? -43.568 -23.577 10.779   1.00 60.88  ? 136 TYR A CZ    1 
ATOM   1052  O OH    . TYR A 1 136 ? -43.399 -23.167 12.072   1.00 57.63  ? 136 TYR A OH    1 
ATOM   1053  N N     . ILE A 1 137 ? -47.160 -23.297 6.127    1.00 47.89  ? 137 ILE A N     1 
ATOM   1054  C CA    . ILE A 1 137 ? -48.163 -22.343 6.546    1.00 47.97  ? 137 ILE A CA    1 
ATOM   1055  C C     . ILE A 1 137 ? -49.498 -23.066 6.591    1.00 43.64  ? 137 ILE A C     1 
ATOM   1056  O O     . ILE A 1 137 ? -50.235 -22.820 7.531    1.00 41.57  ? 137 ILE A O     1 
ATOM   1057  C CB    . ILE A 1 137 ? -48.187 -21.069 5.659    1.00 47.78  ? 137 ILE A CB    1 
ATOM   1058  C CG1   . ILE A 1 137 ? -47.007 -20.160 5.987    1.00 43.73  ? 137 ILE A CG1   1 
ATOM   1059  C CG2   . ILE A 1 137 ? -49.489 -20.289 5.813    1.00 46.56  ? 137 ILE A CG2   1 
ATOM   1060  C CD1   . ILE A 1 137 ? -46.755 -19.110 4.964    1.00 45.09  ? 137 ILE A CD1   1 
ATOM   1061  N N     . GLN A 1 138 ? -49.785 -23.938 5.602    1.00 50.70  ? 138 GLN A N     1 
ATOM   1062  C CA    . GLN A 1 138 ? -51.087 -24.592 5.498    1.00 51.55  ? 138 GLN A CA    1 
ATOM   1063  C C     . GLN A 1 138 ? -51.222 -25.585 6.644    1.00 58.64  ? 138 GLN A C     1 
ATOM   1064  O O     . GLN A 1 138 ? -52.300 -25.685 7.230    1.00 62.31  ? 138 GLN A O     1 
ATOM   1065  C CB    . GLN A 1 138 ? -51.311 -25.310 4.165    1.00 52.44  ? 138 GLN A CB    1 
ATOM   1066  C CG    . GLN A 1 138 ? -51.530 -24.387 2.968    1.00 68.60  ? 138 GLN A CG    1 
ATOM   1067  C CD    . GLN A 1 138 ? -52.812 -23.569 3.005    1.00 83.34  ? 138 GLN A CD    1 
ATOM   1068  O OE1   . GLN A 1 138 ? -53.924 -24.098 3.083    1.00 84.31  ? 138 GLN A OE1   1 
ATOM   1069  N NE2   . GLN A 1 138 ? -52.675 -22.254 2.909    1.00 67.04  ? 138 GLN A NE2   1 
ATOM   1070  N N     . GLU A 1 139 ? -50.114 -26.272 6.956    1.00 58.70  ? 139 GLU A N     1 
ATOM   1071  C CA    . GLU A 1 139 ? -50.099 -27.375 7.904    1.00 67.38  ? 139 GLU A CA    1 
ATOM   1072  C C     . GLU A 1 139 ? -50.367 -26.844 9.307    1.00 62.57  ? 139 GLU A C     1 
ATOM   1073  O O     . GLU A 1 139 ? -51.007 -27.521 10.090   1.00 61.17  ? 139 GLU A O     1 
ATOM   1074  C CB    . GLU A 1 139 ? -48.751 -28.113 7.901    1.00 86.29  ? 139 GLU A CB    1 
ATOM   1075  C CG    . GLU A 1 139 ? -48.476 -28.990 6.669    1.00 109.07 ? 139 GLU A CG    1 
ATOM   1076  C CD    . GLU A 1 139 ? -47.024 -29.441 6.450    1.00 125.93 ? 139 GLU A CD    1 
ATOM   1077  O OE1   . GLU A 1 139 ? -46.737 -30.092 5.400    1.00 104.74 ? 139 GLU A OE1   1 
ATOM   1078  O OE2   . GLU A 1 139 ? -46.160 -29.155 7.321    1.00 123.97 ? 139 GLU A OE2   1 
ATOM   1079  N N     . LYS A 1 140 ? -49.852 -25.650 9.630    1.00 68.10  ? 140 LYS A N     1 
ATOM   1080  C CA    . LYS A 1 140 ? -49.974 -25.080 10.968   1.00 58.99  ? 140 LYS A CA    1 
ATOM   1081  C C     . LYS A 1 140 ? -51.248 -24.243 11.080   1.00 49.60  ? 140 LYS A C     1 
ATOM   1082  O O     . LYS A 1 140 ? -51.542 -23.726 12.157   1.00 51.66  ? 140 LYS A O     1 
ATOM   1083  C CB    . LYS A 1 140 ? -48.769 -24.201 11.316   1.00 61.61  ? 140 LYS A CB    1 
ATOM   1084  C CG    . LYS A 1 140 ? -47.414 -24.892 11.315   1.00 72.75  ? 140 LYS A CG    1 
ATOM   1085  C CD    . LYS A 1 140 ? -47.195 -25.813 12.498   1.00 82.59  ? 140 LYS A CD    1 
ATOM   1086  C CE    . LYS A 1 140 ? -46.114 -26.847 12.253   1.00 86.24  ? 140 LYS A CE    1 
ATOM   1087  N NZ    . LYS A 1 140 ? -46.021 -27.822 13.365   1.00 81.09  ? 140 LYS A NZ    1 
ATOM   1088  N N     . GLY A 1 141 ? -51.975 -24.086 9.966    1.00 45.55  ? 141 GLY A N     1 
ATOM   1089  C CA    . GLY A 1 141 ? -53.260 -23.392 9.936    1.00 49.69  ? 141 GLY A CA    1 
ATOM   1090  C C     . GLY A 1 141 ? -53.179 -21.860 9.990    1.00 51.02  ? 141 GLY A C     1 
ATOM   1091  O O     . GLY A 1 141 ? -54.209 -21.213 10.187   1.00 54.37  ? 141 GLY A O     1 
ATOM   1092  N N     . LEU A 1 142 ? -51.990 -21.278 9.734    1.00 51.30  ? 142 LEU A N     1 
ATOM   1093  C CA    . LEU A 1 142 ? -51.769 -19.835 9.839    1.00 49.24  ? 142 LEU A CA    1 
ATOM   1094  C C     . LEU A 1 142 ? -52.433 -19.083 8.679    1.00 46.79  ? 142 LEU A C     1 
ATOM   1095  O O     . LEU A 1 142 ? -52.357 -19.526 7.537    1.00 49.89  ? 142 LEU A O     1 
ATOM   1096  C CB    . LEU A 1 142 ? -50.266 -19.550 9.867    1.00 45.50  ? 142 LEU A CB    1 
ATOM   1097  C CG    . LEU A 1 142 ? -49.448 -20.278 10.938   1.00 44.80  ? 142 LEU A CG    1 
ATOM   1098  C CD1   . LEU A 1 142 ? -47.967 -19.938 10.819   1.00 44.70  ? 142 LEU A CD1   1 
ATOM   1099  C CD2   . LEU A 1 142 ? -49.936 -19.937 12.330   1.00 45.97  ? 142 LEU A CD2   1 
ATOM   1100  N N     . LYS A 1 143 ? -53.071 -17.938 8.991    1.00 49.41  ? 143 LYS A N     1 
ATOM   1101  C CA    . LYS A 1 143 ? -53.821 -17.130 8.029    1.00 56.33  ? 143 LYS A CA    1 
ATOM   1102  C C     . LYS A 1 143 ? -52.904 -16.106 7.329    1.00 45.09  ? 143 LYS A C     1 
ATOM   1103  O O     . LYS A 1 143 ? -53.063 -14.896 7.444    1.00 43.46  ? 143 LYS A O     1 
ATOM   1104  C CB    . LYS A 1 143 ? -54.997 -16.430 8.733    1.00 59.81  ? 143 LYS A CB    1 
ATOM   1105  C CG    . LYS A 1 143 ? -55.883 -17.303 9.599    1.00 64.99  ? 143 LYS A CG    1 
ATOM   1106  C CD    . LYS A 1 143 ? -56.208 -18.642 8.954    1.00 85.50  ? 143 LYS A CD    1 
ATOM   1107  C CE    . LYS A 1 143 ? -57.280 -19.424 9.691    1.00 97.88  ? 143 LYS A CE    1 
ATOM   1108  N NZ    . LYS A 1 143 ? -57.530 -20.736 9.052    1.00 97.05  ? 143 LYS A NZ    1 
ATOM   1109  N N     . LEU A 1 144 ? -51.930 -16.605 6.581    1.00 39.68  ? 144 LEU A N     1 
ATOM   1110  C CA    . LEU A 1 144 ? -50.981 -15.773 5.884    1.00 40.73  ? 144 LEU A CA    1 
ATOM   1111  C C     . LEU A 1 144 ? -50.932 -16.272 4.454    1.00 41.17  ? 144 LEU A C     1 
ATOM   1112  O O     . LEU A 1 144 ? -51.033 -17.473 4.255    1.00 36.95  ? 144 LEU A O     1 
ATOM   1113  C CB    . LEU A 1 144 ? -49.610 -15.930 6.532    1.00 36.66  ? 144 LEU A CB    1 
ATOM   1114  C CG    . LEU A 1 144 ? -49.459 -15.498 7.989    1.00 37.86  ? 144 LEU A CG    1 
ATOM   1115  C CD1   . LEU A 1 144 ? -48.086 -15.881 8.472    1.00 39.22  ? 144 LEU A CD1   1 
ATOM   1116  C CD2   . LEU A 1 144 ? -49.657 -13.991 8.174    1.00 38.71  ? 144 LEU A CD2   1 
ATOM   1117  N N     . TRP A 1 145 ? -50.790 -15.342 3.503    1.00 42.27  ? 145 TRP A N     1 
ATOM   1118  C CA    . TRP A 1 145 ? -50.505 -15.667 2.114    1.00 38.01  ? 145 TRP A CA    1 
ATOM   1119  C C     . TRP A 1 145 ? -49.033 -15.428 1.836    1.00 40.94  ? 145 TRP A C     1 
ATOM   1120  O O     . TRP A 1 145 ? -48.376 -14.610 2.495    1.00 44.77  ? 145 TRP A O     1 
ATOM   1121  C CB    . TRP A 1 145 ? -51.356 -14.821 1.175    1.00 41.17  ? 145 TRP A CB    1 
ATOM   1122  C CG    . TRP A 1 145 ? -52.794 -15.236 1.136    1.00 43.76  ? 145 TRP A CG    1 
ATOM   1123  C CD1   . TRP A 1 145 ? -53.413 -16.170 1.920    1.00 44.22  ? 145 TRP A CD1   1 
ATOM   1124  C CD2   . TRP A 1 145 ? -53.797 -14.739 0.235    1.00 42.48  ? 145 TRP A CD2   1 
ATOM   1125  N NE1   . TRP A 1 145 ? -54.732 -16.281 1.565    1.00 49.64  ? 145 TRP A NE1   1 
ATOM   1126  C CE2   . TRP A 1 145 ? -54.993 -15.433 0.528    1.00 46.75  ? 145 TRP A CE2   1 
ATOM   1127  C CE3   . TRP A 1 145 ? -53.793 -13.781 -0.788   1.00 38.84  ? 145 TRP A CE3   1 
ATOM   1128  C CZ2   . TRP A 1 145 ? -56.184 -15.188 -0.151   1.00 47.73  ? 145 TRP A CZ2   1 
ATOM   1129  C CZ3   . TRP A 1 145 ? -54.963 -13.539 -1.459   1.00 44.10  ? 145 TRP A CZ3   1 
ATOM   1130  C CH2   . TRP A 1 145 ? -56.140 -14.242 -1.153   1.00 46.75  ? 145 TRP A CH2   1 
ATOM   1131  N N     . ILE A 1 146 ? -48.512 -16.183 0.867    1.00 39.43  ? 146 ILE A N     1 
ATOM   1132  C CA    . ILE A 1 146 ? -47.174 -15.918 0.390    1.00 35.09  ? 146 ILE A CA    1 
ATOM   1133  C C     . ILE A 1 146 ? -47.351 -15.279 -0.971   1.00 37.10  ? 146 ILE A C     1 
ATOM   1134  O O     . ILE A 1 146 ? -48.485 -15.043 -1.403   1.00 34.94  ? 146 ILE A O     1 
ATOM   1135  C CB    . ILE A 1 146 ? -46.287 -17.173 0.433    1.00 40.05  ? 146 ILE A CB    1 
ATOM   1136  C CG1   . ILE A 1 146 ? -46.742 -18.284 -0.511   1.00 39.11  ? 146 ILE A CG1   1 
ATOM   1137  C CG2   . ILE A 1 146 ? -46.183 -17.722 1.853    1.00 41.63  ? 146 ILE A CG2   1 
ATOM   1138  C CD1   . ILE A 1 146 ? -45.646 -19.285 -0.756   1.00 36.29  ? 146 ILE A CD1   1 
ATOM   1139  N N     . ASP A 1 147 ? -46.236 -14.885 -1.582   1.00 43.64  ? 147 ASP A N     1 
ATOM   1140  C CA    . ASP A 1 147 ? -46.291 -14.308 -2.912   1.00 43.20  ? 147 ASP A CA    1 
ATOM   1141  C C     . ASP A 1 147 ? -45.311 -15.067 -3.806   1.00 40.65  ? 147 ASP A C     1 
ATOM   1142  O O     . ASP A 1 147 ? -44.109 -15.096 -3.552   1.00 36.00  ? 147 ASP A O     1 
ATOM   1143  C CB    . ASP A 1 147 ? -46.019 -12.807 -2.834   1.00 43.02  ? 147 ASP A CB    1 
ATOM   1144  C CG    . ASP A 1 147 ? -46.211 -12.141 -4.187   1.00 45.42  ? 147 ASP A CG    1 
ATOM   1145  O OD1   . ASP A 1 147 ? -45.366 -12.403 -5.099   1.00 37.85  ? 147 ASP A OD1   1 
ATOM   1146  O OD2   . ASP A 1 147 ? -47.224 -11.398 -4.326   1.00 43.23  ? 147 ASP A OD2   1 
ATOM   1147  N N     . VAL A 1 148 ? -45.838 -15.724 -4.836   1.00 38.22  ? 148 VAL A N     1 
ATOM   1148  C CA    . VAL A 1 148 ? -45.029 -16.687 -5.563   1.00 35.95  ? 148 VAL A CA    1 
ATOM   1149  C C     . VAL A 1 148 ? -44.797 -16.174 -6.963   1.00 41.09  ? 148 VAL A C     1 
ATOM   1150  O O     . VAL A 1 148 ? -45.662 -15.492 -7.534   1.00 44.33  ? 148 VAL A O     1 
ATOM   1151  C CB    . VAL A 1 148 ? -45.675 -18.080 -5.612   1.00 36.71  ? 148 VAL A CB    1 
ATOM   1152  C CG1   . VAL A 1 148 ? -45.796 -18.676 -4.209   1.00 40.00  ? 148 VAL A CG1   1 
ATOM   1153  C CG2   . VAL A 1 148 ? -47.037 -18.053 -6.309   1.00 36.99  ? 148 VAL A CG2   1 
ATOM   1154  N N     . PRO A 1 149 ? -43.631 -16.529 -7.543   1.00 45.26  ? 149 PRO A N     1 
ATOM   1155  C CA    . PRO A 1 149 ? -43.412 -16.398 -8.985   1.00 51.23  ? 149 PRO A CA    1 
ATOM   1156  C C     . PRO A 1 149 ? -44.219 -17.491 -9.670   1.00 56.74  ? 149 PRO A C     1 
ATOM   1157  O O     . PRO A 1 149 ? -44.933 -18.229 -9.004   1.00 61.28  ? 149 PRO A O     1 
ATOM   1158  C CB    . PRO A 1 149 ? -41.897 -16.570 -9.103   1.00 49.05  ? 149 PRO A CB    1 
ATOM   1159  C CG    . PRO A 1 149 ? -41.551 -17.501 -7.955   1.00 53.03  ? 149 PRO A CG    1 
ATOM   1160  C CD    . PRO A 1 149 ? -42.471 -17.085 -6.831   1.00 46.37  ? 149 PRO A CD    1 
ATOM   1161  N N     . ASP A 1 150 ? -44.066 -17.640 -10.985  1.00 72.32  ? 150 ASP A N     1 
ATOM   1162  C CA    . ASP A 1 150 ? -44.846 -18.619 -11.725  1.00 71.78  ? 150 ASP A CA    1 
ATOM   1163  C C     . ASP A 1 150 ? -44.328 -20.038 -11.486  1.00 74.26  ? 150 ASP A C     1 
ATOM   1164  O O     . ASP A 1 150 ? -45.068 -20.992 -11.703  1.00 104.81 ? 150 ASP A O     1 
ATOM   1165  C CB    . ASP A 1 150 ? -44.899 -18.264 -13.212  1.00 80.15  ? 150 ASP A CB    1 
ATOM   1166  C CG    . ASP A 1 150 ? -45.953 -17.229 -13.599  1.00 85.67  ? 150 ASP A CG    1 
ATOM   1167  O OD1   . ASP A 1 150 ? -47.171 -17.451 -13.279  1.00 78.87  ? 150 ASP A OD1   1 
ATOM   1168  O OD2   . ASP A 1 150 ? -45.564 -16.230 -14.269  1.00 78.36  ? 150 ASP A OD2   1 
ATOM   1169  N N     . GLY A 1 151 ? -43.090 -20.206 -11.003  1.00 78.10  ? 151 GLY A N     1 
ATOM   1170  C CA    . GLY A 1 151 ? -42.658 -21.514 -10.512  1.00 75.40  ? 151 GLY A CA    1 
ATOM   1171  C C     . GLY A 1 151 ? -42.176 -21.508 -9.055   1.00 68.64  ? 151 GLY A C     1 
ATOM   1172  O O     . GLY A 1 151 ? -41.153 -20.891 -8.700   1.00 79.04  ? 151 GLY A O     1 
ATOM   1173  N N     . GLY A 1 152 ? -42.852 -22.321 -8.244   1.00 55.38  ? 152 GLY A N     1 
ATOM   1174  C CA    . GLY A 1 152 ? -42.647 -22.343 -6.799   1.00 60.22  ? 152 GLY A CA    1 
ATOM   1175  C C     . GLY A 1 152 ? -41.600 -23.332 -6.263   1.00 59.83  ? 152 GLY A C     1 
ATOM   1176  O O     . GLY A 1 152 ? -41.487 -23.513 -5.046   1.00 57.03  ? 152 GLY A O     1 
ATOM   1177  N N     . TRP A 1 153 ? -40.767 -23.912 -7.132   1.00 64.57  ? 153 TRP A N     1 
ATOM   1178  C CA    . TRP A 1 153 ? -39.702 -24.813 -6.692   1.00 80.36  ? 153 TRP A CA    1 
ATOM   1179  C C     . TRP A 1 153 ? -38.438 -24.046 -6.301   1.00 70.95  ? 153 TRP A C     1 
ATOM   1180  O O     . TRP A 1 153 ? -37.487 -24.692 -5.835   1.00 65.19  ? 153 TRP A O     1 
ATOM   1181  C CB    . TRP A 1 153 ? -39.378 -25.849 -7.775   1.00 97.41  ? 153 TRP A CB    1 
ATOM   1182  C CG    . TRP A 1 153 ? -39.356 -25.256 -9.153   1.00 127.24 ? 153 TRP A CG    1 
ATOM   1183  C CD1   . TRP A 1 153 ? -38.928 -24.006 -9.516   1.00 126.29 ? 153 TRP A CD1   1 
ATOM   1184  C CD2   . TRP A 1 153 ? -39.801 -25.896 -10.362  1.00 137.08 ? 153 TRP A CD2   1 
ATOM   1185  N NE1   . TRP A 1 153 ? -39.078 -23.822 -10.862  1.00 122.34 ? 153 TRP A NE1   1 
ATOM   1186  C CE2   . TRP A 1 153 ? -39.601 -24.968 -11.406  1.00 135.56 ? 153 TRP A CE2   1 
ATOM   1187  C CE3   . TRP A 1 153 ? -40.334 -27.157 -10.661  1.00 129.72 ? 153 TRP A CE3   1 
ATOM   1188  C CZ2   . TRP A 1 153 ? -39.913 -25.277 -12.728  1.00 143.55 ? 153 TRP A CZ2   1 
ATOM   1189  C CZ3   . TRP A 1 153 ? -40.637 -27.459 -11.970  1.00 129.26 ? 153 TRP A CZ3   1 
ATOM   1190  C CH2   . TRP A 1 153 ? -40.431 -26.527 -12.987  1.00 133.91 ? 153 TRP A CH2   1 
ATOM   1191  N N     . GLY A 1 154 ? -38.470 -22.707 -6.514   1.00 53.99  ? 154 GLY A N     1 
ATOM   1192  C CA    . GLY A 1 154 ? -37.361 -21.795 -6.295   1.00 51.96  ? 154 GLY A CA    1 
ATOM   1193  C C     . GLY A 1 154 ? -37.377 -21.166 -4.899   1.00 51.45  ? 154 GLY A C     1 
ATOM   1194  O O     . GLY A 1 154 ? -38.223 -21.488 -4.064   1.00 51.99  ? 154 GLY A O     1 
ATOM   1195  N N     . SER A 1 155 ? -36.393 -20.291 -4.655   1.00 42.88  ? 155 SER A N     1 
ATOM   1196  C CA    . SER A 1 155 ? -35.993 -19.845 -3.327   1.00 40.03  ? 155 SER A CA    1 
ATOM   1197  C C     . SER A 1 155 ? -36.650 -18.518 -2.953   1.00 38.13  ? 155 SER A C     1 
ATOM   1198  O O     . SER A 1 155 ? -36.489 -17.513 -3.652   1.00 43.27  ? 155 SER A O     1 
ATOM   1199  C CB    . SER A 1 155 ? -34.498 -19.682 -3.314   1.00 43.94  ? 155 SER A CB    1 
ATOM   1200  O OG    . SER A 1 155 ? -34.052 -19.130 -2.080   1.00 48.23  ? 155 SER A OG    1 
ATOM   1201  N N     . VAL A 1 156 ? -37.344 -18.486 -1.823   1.00 37.59  ? 156 VAL A N     1 
ATOM   1202  C CA    . VAL A 1 156 ? -37.837 -17.227 -1.278   1.00 38.28  ? 156 VAL A CA    1 
ATOM   1203  C C     . VAL A 1 156 ? -36.703 -16.203 -1.223   1.00 39.16  ? 156 VAL A C     1 
ATOM   1204  O O     . VAL A 1 156 ? -36.892 -15.062 -1.629   1.00 36.52  ? 156 VAL A O     1 
ATOM   1205  C CB    . VAL A 1 156 ? -38.449 -17.429 0.115    1.00 39.19  ? 156 VAL A CB    1 
ATOM   1206  C CG1   . VAL A 1 156 ? -38.912 -16.112 0.719    1.00 44.24  ? 156 VAL A CG1   1 
ATOM   1207  C CG2   . VAL A 1 156 ? -39.605 -18.395 0.058    1.00 42.34  ? 156 VAL A CG2   1 
ATOM   1208  N N     . VAL A 1 157 ? -35.516 -16.618 -0.736   1.00 38.77  ? 157 VAL A N     1 
ATOM   1209  C CA    . VAL A 1 157 ? -34.377 -15.715 -0.633   1.00 35.61  ? 157 VAL A CA    1 
ATOM   1210  C C     . VAL A 1 157 ? -33.859 -15.335 -2.025   1.00 38.33  ? 157 VAL A C     1 
ATOM   1211  O O     . VAL A 1 157 ? -33.852 -14.165 -2.403   1.00 44.78  ? 157 VAL A O     1 
ATOM   1212  C CB    . VAL A 1 157 ? -33.271 -16.296 0.271    1.00 30.02  ? 157 VAL A CB    1 
ATOM   1213  C CG1   . VAL A 1 157 ? -32.022 -15.444 0.294    1.00 30.01  ? 157 VAL A CG1   1 
ATOM   1214  C CG2   . VAL A 1 157 ? -33.760 -16.459 1.692    1.00 31.85  ? 157 VAL A CG2   1 
ATOM   1215  N N     . GLY A 1 158 ? -33.415 -16.324 -2.797   1.00 42.76  ? 158 GLY A N     1 
ATOM   1216  C CA    . GLY A 1 158 ? -32.714 -16.078 -4.052   1.00 42.95  ? 158 GLY A CA    1 
ATOM   1217  C C     . GLY A 1 158 ? -33.519 -15.238 -5.033   1.00 34.39  ? 158 GLY A C     1 
ATOM   1218  O O     . GLY A 1 158 ? -33.029 -14.328 -5.669   1.00 36.03  ? 158 GLY A O     1 
ATOM   1219  N N     . ASN A 1 159 ? -34.801 -15.518 -5.098   1.00 40.01  ? 159 ASN A N     1 
ATOM   1220  C CA    . ASN A 1 159 ? -35.668 -14.764 -5.975   1.00 38.44  ? 159 ASN A CA    1 
ATOM   1221  C C     . ASN A 1 159 ? -35.765 -13.311 -5.494   1.00 37.77  ? 159 ASN A C     1 
ATOM   1222  O O     . ASN A 1 159 ? -35.730 -12.376 -6.297   1.00 41.53  ? 159 ASN A O     1 
ATOM   1223  C CB    . ASN A 1 159 ? -36.997 -15.496 -6.063   1.00 40.56  ? 159 ASN A CB    1 
ATOM   1224  C CG    . ASN A 1 159 ? -38.039 -14.659 -6.748   1.00 45.56  ? 159 ASN A CG    1 
ATOM   1225  O OD1   . ASN A 1 159 ? -38.487 -13.655 -6.196   1.00 56.13  ? 159 ASN A OD1   1 
ATOM   1226  N ND2   . ASN A 1 159 ? -38.419 -15.068 -7.937   1.00 41.34  ? 159 ASN A ND2   1 
ATOM   1227  N N     . ALA A 1 160 ? -35.877 -13.096 -4.177   1.00 36.07  ? 160 ALA A N     1 
ATOM   1228  C CA    . ALA A 1 160 ? -35.968 -11.744 -3.656   1.00 29.61  ? 160 ALA A CA    1 
ATOM   1229  C C     . ALA A 1 160 ? -34.633 -11.060 -3.911   1.00 32.68  ? 160 ALA A C     1 
ATOM   1230  O O     . ALA A 1 160 ? -34.597 -9.904  -4.313   1.00 32.44  ? 160 ALA A O     1 
ATOM   1231  C CB    . ALA A 1 160 ? -36.330 -11.754 -2.195   1.00 29.83  ? 160 ALA A CB    1 
ATOM   1232  N N     . LEU A 1 161 ? -33.512 -11.782 -3.763   1.00 33.16  ? 161 LEU A N     1 
ATOM   1233  C CA    . LEU A 1 161 ? -32.263 -11.072 -3.937   1.00 35.26  ? 161 LEU A CA    1 
ATOM   1234  C C     . LEU A 1 161 ? -32.138 -10.666 -5.393   1.00 38.65  ? 161 LEU A C     1 
ATOM   1235  O O     . LEU A 1 161 ? -31.516 -9.636  -5.666   1.00 37.91  ? 161 LEU A O     1 
ATOM   1236  C CB    . LEU A 1 161 ? -31.085 -11.901 -3.419   1.00 38.29  ? 161 LEU A CB    1 
ATOM   1237  C CG    . LEU A 1 161 ? -31.087 -12.067 -1.894   1.00 39.16  ? 161 LEU A CG    1 
ATOM   1238  C CD1   . LEU A 1 161 ? -29.954 -12.964 -1.479   1.00 46.38  ? 161 LEU A CD1   1 
ATOM   1239  C CD2   . LEU A 1 161 ? -30.967 -10.723 -1.169   1.00 36.47  ? 161 LEU A CD2   1 
ATOM   1240  N N     . ASP A 1 162 ? -32.792 -11.413 -6.305   1.00 38.94  ? 162 ASP A N     1 
ATOM   1241  C CA    . ASP A 1 162 ? -32.647 -11.097 -7.723   1.00 44.58  ? 162 ASP A CA    1 
ATOM   1242  C C     . ASP A 1 162 ? -33.689 -10.080 -8.195   1.00 38.58  ? 162 ASP A C     1 
ATOM   1243  O O     . ASP A 1 162 ? -33.783 -9.840  -9.382   1.00 41.99  ? 162 ASP A O     1 
ATOM   1244  C CB    . ASP A 1 162 ? -32.682 -12.352 -8.610   1.00 44.77  ? 162 ASP A CB    1 
ATOM   1245  C CG    . ASP A 1 162 ? -31.689 -12.316 -9.771   1.00 50.22  ? 162 ASP A CG    1 
ATOM   1246  O OD1   . ASP A 1 162 ? -30.734 -11.498 -9.694   1.00 54.98  ? 162 ASP A OD1   1 
ATOM   1247  O OD2   . ASP A 1 162 ? -31.829 -13.145 -10.725  1.00 51.27  ? 162 ASP A OD2   1 
ATOM   1248  N N     . HIS A 1 163 ? -34.463 -9.496  -7.286   1.00 36.42  ? 163 HIS A N     1 
ATOM   1249  C CA    . HIS A 1 163 ? -35.509 -8.524  -7.617   1.00 38.62  ? 163 HIS A CA    1 
ATOM   1250  C C     . HIS A 1 163 ? -36.705 -9.191  -8.291   1.00 40.61  ? 163 HIS A C     1 
ATOM   1251  O O     . HIS A 1 163 ? -37.336 -8.611  -9.166   1.00 46.35  ? 163 HIS A O     1 
ATOM   1252  C CB    . HIS A 1 163 ? -34.992 -7.316  -8.408   1.00 37.06  ? 163 HIS A CB    1 
ATOM   1253  C CG    . HIS A 1 163 ? -33.969 -6.535  -7.673   1.00 35.83  ? 163 HIS A CG    1 
ATOM   1254  N ND1   . HIS A 1 163 ? -33.119 -5.675  -8.308   1.00 31.70  ? 163 HIS A ND1   1 
ATOM   1255  C CD2   . HIS A 1 163 ? -33.586 -6.563  -6.372   1.00 36.83  ? 163 HIS A CD2   1 
ATOM   1256  C CE1   . HIS A 1 163 ? -32.296 -5.153  -7.404   1.00 37.57  ? 163 HIS A CE1   1 
ATOM   1257  N NE2   . HIS A 1 163 ? -32.576 -5.665  -6.211   1.00 35.01  ? 163 HIS A NE2   1 
ATOM   1258  N N     . GLY A 1 164 ? -37.079 -10.372 -7.797   1.00 45.83  ? 164 GLY A N     1 
ATOM   1259  C CA    . GLY A 1 164 ? -38.200 -11.126 -8.334   1.00 49.42  ? 164 GLY A CA    1 
ATOM   1260  C C     . GLY A 1 164 ? -39.551 -10.473 -8.081   1.00 47.67  ? 164 GLY A C     1 
ATOM   1261  O O     . GLY A 1 164 ? -39.680 -9.621  -7.211   1.00 59.22  ? 164 GLY A O     1 
ATOM   1262  N N     . ILE A 1 165 ? -40.554 -10.927 -8.835   1.00 50.95  ? 165 ILE A N     1 
ATOM   1263  C CA    . ILE A 1 165 ? -41.914 -10.414 -8.745   1.00 52.81  ? 165 ILE A CA    1 
ATOM   1264  C C     . ILE A 1 165 ? -42.910 -11.560 -8.584   1.00 50.87  ? 165 ILE A C     1 
ATOM   1265  O O     . ILE A 1 165 ? -42.681 -12.688 -9.017   1.00 59.27  ? 165 ILE A O     1 
ATOM   1266  C CB    . ILE A 1 165 ? -42.284 -9.593  -9.991   1.00 53.48  ? 165 ILE A CB    1 
ATOM   1267  C CG1   . ILE A 1 165 ? -42.266 -10.484 -11.244  1.00 66.75  ? 165 ILE A CG1   1 
ATOM   1268  C CG2   . ILE A 1 165 ? -41.383 -8.367  -10.089  1.00 50.14  ? 165 ILE A CG2   1 
ATOM   1269  C CD1   . ILE A 1 165 ? -43.092 -9.980  -12.432  1.00 81.58  ? 165 ILE A CD1   1 
ATOM   1270  N N     . GLY A 1 166 ? -44.067 -11.214 -8.034   1.00 42.89  ? 166 GLY A N     1 
ATOM   1271  C CA    . GLY A 1 166 ? -45.222 -12.086 -7.999   1.00 35.86  ? 166 GLY A CA    1 
ATOM   1272  C C     . GLY A 1 166 ? -46.469 -11.283 -8.329   1.00 36.52  ? 166 GLY A C     1 
ATOM   1273  O O     . GLY A 1 166 ? -46.365 -10.201 -8.917   1.00 35.69  ? 166 GLY A O     1 
ATOM   1274  N N     . TYR A 1 167 ? -47.634 -11.834 -7.958   1.00 35.14  ? 167 TYR A N     1 
ATOM   1275  C CA    . TYR A 1 167 ? -48.894 -11.417 -8.551   1.00 35.16  ? 167 TYR A CA    1 
ATOM   1276  C C     . TYR A 1 167 ? -49.944 -11.131 -7.478   1.00 35.01  ? 167 TYR A C     1 
ATOM   1277  O O     . TYR A 1 167 ? -51.112 -11.066 -7.809   1.00 34.12  ? 167 TYR A O     1 
ATOM   1278  C CB    . TYR A 1 167 ? -49.334 -12.480 -9.565   1.00 38.02  ? 167 TYR A CB    1 
ATOM   1279  C CG    . TYR A 1 167 ? -48.282 -12.751 -10.602  1.00 38.96  ? 167 TYR A CG    1 
ATOM   1280  C CD1   . TYR A 1 167 ? -48.129 -11.919 -11.702  1.00 44.06  ? 167 TYR A CD1   1 
ATOM   1281  C CD2   . TYR A 1 167 ? -47.366 -13.778 -10.430  1.00 41.07  ? 167 TYR A CD2   1 
ATOM   1282  C CE1   . TYR A 1 167 ? -47.109 -12.115 -12.626  1.00 45.34  ? 167 TYR A CE1   1 
ATOM   1283  C CE2   . TYR A 1 167 ? -46.347 -13.997 -11.343  1.00 43.08  ? 167 TYR A CE2   1 
ATOM   1284  C CZ    . TYR A 1 167 ? -46.217 -13.169 -12.455  1.00 52.49  ? 167 TYR A CZ    1 
ATOM   1285  O OH    . TYR A 1 167 ? -45.193 -13.416 -13.377  1.00 50.12  ? 167 TYR A OH    1 
ATOM   1286  N N     . THR A 1 168 ? -49.512 -10.959 -6.220   1.00 37.21  ? 168 THR A N     1 
ATOM   1287  C CA    . THR A 1 168 ? -50.331 -10.410 -5.153   1.00 38.70  ? 168 THR A CA    1 
ATOM   1288  C C     . THR A 1 168 ? -49.844 -9.004  -4.812   1.00 38.61  ? 168 THR A C     1 
ATOM   1289  O O     . THR A 1 168 ? -48.812 -8.504  -5.295   1.00 31.43  ? 168 THR A O     1 
ATOM   1290  C CB    . THR A 1 168 ? -50.315 -11.297 -3.882   1.00 40.86  ? 168 THR A CB    1 
ATOM   1291  O OG1   . THR A 1 168 ? -49.290 -10.940 -2.950   1.00 37.11  ? 168 THR A OG1   1 
ATOM   1292  C CG2   . THR A 1 168 ? -50.186 -12.779 -4.195   1.00 40.02  ? 168 THR A CG2   1 
ATOM   1293  N N     . PRO A 1 169 ? -50.517 -8.316  -3.870   1.00 38.94  ? 169 PRO A N     1 
ATOM   1294  C CA    . PRO A 1 169 ? -50.042 -6.996  -3.469   1.00 39.25  ? 169 PRO A CA    1 
ATOM   1295  C C     . PRO A 1 169 ? -48.623 -7.019  -2.878   1.00 38.27  ? 169 PRO A C     1 
ATOM   1296  O O     . PRO A 1 169 ? -47.991 -5.959  -2.731   1.00 33.69  ? 169 PRO A O     1 
ATOM   1297  C CB    . PRO A 1 169 ? -51.124 -6.571  -2.475   1.00 37.37  ? 169 PRO A CB    1 
ATOM   1298  C CG    . PRO A 1 169 ? -52.348 -7.369  -2.887   1.00 39.30  ? 169 PRO A CG    1 
ATOM   1299  C CD    . PRO A 1 169 ? -51.748 -8.722  -3.186   1.00 41.02  ? 169 PRO A CD    1 
ATOM   1300  N N     . TYR A 1 170 ? -48.138 -8.220  -2.508   1.00 31.19  ? 170 TYR A N     1 
ATOM   1301  C CA    . TYR A 1 170 ? -46.789 -8.363  -2.007   1.00 31.61  ? 170 TYR A CA    1 
ATOM   1302  C C     . TYR A 1 170 ? -45.869 -8.774  -3.153   1.00 32.72  ? 170 TYR A C     1 
ATOM   1303  O O     . TYR A 1 170 ? -44.781 -9.325  -2.953   1.00 34.46  ? 170 TYR A O     1 
ATOM   1304  C CB    . TYR A 1 170 ? -46.753 -9.265  -0.772   1.00 32.23  ? 170 TYR A CB    1 
ATOM   1305  C CG    . TYR A 1 170 ? -47.210 -8.669  0.539    1.00 31.04  ? 170 TYR A CG    1 
ATOM   1306  C CD1   . TYR A 1 170 ? -48.316 -7.856  0.620    1.00 37.55  ? 170 TYR A CD1   1 
ATOM   1307  C CD2   . TYR A 1 170 ? -46.560 -8.961  1.732    1.00 37.85  ? 170 TYR A CD2   1 
ATOM   1308  C CE1   . TYR A 1 170 ? -48.767 -7.356  1.837    1.00 38.47  ? 170 TYR A CE1   1 
ATOM   1309  C CE2   . TYR A 1 170 ? -46.969 -8.447  2.958    1.00 34.27  ? 170 TYR A CE2   1 
ATOM   1310  C CZ    . TYR A 1 170 ? -48.111 -7.681  3.009    1.00 32.64  ? 170 TYR A CZ    1 
ATOM   1311  O OH    . TYR A 1 170 ? -48.580 -7.186  4.163    1.00 28.01  ? 170 TYR A OH    1 
ATOM   1312  N N     . GLY A 1 171 ? -46.250 -8.359  -4.365   1.00 37.61  ? 171 GLY A N     1 
ATOM   1313  C CA    . GLY A 1 171 ? -45.571 -8.785  -5.583   1.00 34.14  ? 171 GLY A CA    1 
ATOM   1314  C C     . GLY A 1 171 ? -44.118 -8.344  -5.655   1.00 33.22  ? 171 GLY A C     1 
ATOM   1315  O O     . GLY A 1 171 ? -43.339 -8.976  -6.346   1.00 37.96  ? 171 GLY A O     1 
ATOM   1316  N N     . ASP A 1 172 ? -43.751 -7.237  -5.012   1.00 35.42  ? 172 ASP A N     1 
ATOM   1317  C CA    . ASP A 1 172 ? -42.370 -6.773  -5.096   1.00 37.24  ? 172 ASP A CA    1 
ATOM   1318  C C     . ASP A 1 172 ? -41.556 -7.456  -3.984   1.00 39.35  ? 172 ASP A C     1 
ATOM   1319  O O     . ASP A 1 172 ? -41.448 -6.940  -2.874   1.00 39.78  ? 172 ASP A O     1 
ATOM   1320  C CB    . ASP A 1 172 ? -42.316 -5.237  -5.119   1.00 33.19  ? 172 ASP A CB    1 
ATOM   1321  C CG    . ASP A 1 172 ? -40.935 -4.611  -5.352   1.00 37.16  ? 172 ASP A CG    1 
ATOM   1322  O OD1   . ASP A 1 172 ? -39.895 -5.310  -5.142   1.00 38.54  ? 172 ASP A OD1   1 
ATOM   1323  O OD2   . ASP A 1 172 ? -40.892 -3.419  -5.765   1.00 37.75  ? 172 ASP A OD2   1 
ATOM   1324  N N     . HIS A 1 173 ? -40.920 -8.592  -4.303   1.00 38.13  ? 173 HIS A N     1 
ATOM   1325  C CA    . HIS A 1 173 ? -40.344 -9.451  -3.273   1.00 38.96  ? 173 HIS A CA    1 
ATOM   1326  C C     . HIS A 1 173 ? -39.259 -8.745  -2.459   1.00 37.87  ? 173 HIS A C     1 
ATOM   1327  O O     . HIS A 1 173 ? -39.201 -8.837  -1.241   1.00 39.41  ? 173 HIS A O     1 
ATOM   1328  C CB    . HIS A 1 173 ? -39.827 -10.766 -3.871   1.00 37.53  ? 173 HIS A CB    1 
ATOM   1329  C CG    . HIS A 1 173 ? -40.897 -11.622 -4.440   1.00 36.31  ? 173 HIS A CG    1 
ATOM   1330  N ND1   . HIS A 1 173 ? -40.610 -12.711 -5.217   1.00 37.32  ? 173 HIS A ND1   1 
ATOM   1331  C CD2   . HIS A 1 173 ? -42.245 -11.552 -4.389   1.00 43.48  ? 173 HIS A CD2   1 
ATOM   1332  C CE1   . HIS A 1 173 ? -41.739 -13.260 -5.634   1.00 39.99  ? 173 HIS A CE1   1 
ATOM   1333  N NE2   . HIS A 1 173 ? -42.753 -12.574 -5.140   1.00 42.75  ? 173 HIS A NE2   1 
ATOM   1334  N N     . PHE A 1 174 ? -38.337 -8.063  -3.109   1.00 37.91  ? 174 PHE A N     1 
ATOM   1335  C CA    . PHE A 1 174 ? -37.274 -7.486  -2.313   1.00 40.78  ? 174 PHE A CA    1 
ATOM   1336  C C     . PHE A 1 174 ? -37.846 -6.349  -1.465   1.00 40.89  ? 174 PHE A C     1 
ATOM   1337  O O     . PHE A 1 174 ? -37.346 -6.061  -0.386   1.00 38.49  ? 174 PHE A O     1 
ATOM   1338  C CB    . PHE A 1 174 ? -36.083 -7.056  -3.173   1.00 42.98  ? 174 PHE A CB    1 
ATOM   1339  C CG    . PHE A 1 174 ? -34.884 -6.757  -2.322   1.00 45.53  ? 174 PHE A CG    1 
ATOM   1340  C CD1   . PHE A 1 174 ? -34.289 -7.769  -1.580   1.00 49.43  ? 174 PHE A CD1   1 
ATOM   1341  C CD2   . PHE A 1 174 ? -34.439 -5.460  -2.160   1.00 42.37  ? 174 PHE A CD2   1 
ATOM   1342  C CE1   . PHE A 1 174 ? -33.235 -7.493  -0.725   1.00 43.75  ? 174 PHE A CE1   1 
ATOM   1343  C CE2   . PHE A 1 174 ? -33.385 -5.192  -1.306   1.00 44.17  ? 174 PHE A CE2   1 
ATOM   1344  C CZ    . PHE A 1 174 ? -32.787 -6.204  -0.595   1.00 41.97  ? 174 PHE A CZ    1 
ATOM   1345  N N     . ALA A 1 175 ? -38.916 -5.705  -1.941   1.00 41.28  ? 175 ALA A N     1 
ATOM   1346  C CA    . ALA A 1 175 ? -39.472 -4.575  -1.209   1.00 34.70  ? 175 ALA A CA    1 
ATOM   1347  C C     . ALA A 1 175 ? -40.015 -5.036  0.138    1.00 36.15  ? 175 ALA A C     1 
ATOM   1348  O O     . ALA A 1 175 ? -40.099 -4.238  1.057    1.00 33.94  ? 175 ALA A O     1 
ATOM   1349  C CB    . ALA A 1 175 ? -40.545 -3.898  -2.017   1.00 33.23  ? 175 ALA A CB    1 
ATOM   1350  N N     . MET A 1 176 ? -40.384 -6.324  0.232    1.00 37.82  ? 176 MET A N     1 
ATOM   1351  C CA    . MET A 1 176 ? -41.025 -6.869  1.418    1.00 36.11  ? 176 MET A CA    1 
ATOM   1352  C C     . MET A 1 176 ? -39.983 -7.554  2.295    1.00 34.44  ? 176 MET A C     1 
ATOM   1353  O O     . MET A 1 176 ? -40.336 -8.097  3.343    1.00 33.99  ? 176 MET A O     1 
ATOM   1354  C CB    . MET A 1 176 ? -42.111 -7.892  1.046    1.00 35.76  ? 176 MET A CB    1 
ATOM   1355  C CG    . MET A 1 176 ? -43.237 -7.351  0.197    1.00 34.77  ? 176 MET A CG    1 
ATOM   1356  S SD    . MET A 1 176 ? -44.288 -6.083  0.968    1.00 41.02  ? 176 MET A SD    1 
ATOM   1357  C CE    . MET A 1 176 ? -43.466 -4.582  0.446    1.00 40.49  ? 176 MET A CE    1 
ATOM   1358  N N     . GLN A 1 177 ? -38.712 -7.544  1.849    1.00 37.88  ? 177 GLN A N     1 
ATOM   1359  C CA    . GLN A 1 177 ? -37.604 -8.100  2.615    1.00 33.11  ? 177 GLN A CA    1 
ATOM   1360  C C     . GLN A 1 177 ? -37.362 -7.228  3.834    1.00 32.92  ? 177 GLN A C     1 
ATOM   1361  O O     . GLN A 1 177 ? -37.403 -6.011  3.757    1.00 31.62  ? 177 GLN A O     1 
ATOM   1362  C CB    . GLN A 1 177 ? -36.332 -8.173  1.779    1.00 33.04  ? 177 GLN A CB    1 
ATOM   1363  C CG    . GLN A 1 177 ? -35.110 -8.705  2.524    1.00 37.99  ? 177 GLN A CG    1 
ATOM   1364  C CD    . GLN A 1 177 ? -34.258 -7.613  3.115    1.00 35.40  ? 177 GLN A CD    1 
ATOM   1365  O OE1   . GLN A 1 177 ? -34.118 -6.541  2.557    1.00 43.48  ? 177 GLN A OE1   1 
ATOM   1366  N NE2   . GLN A 1 177 ? -33.719 -7.837  4.293    1.00 45.41  ? 177 GLN A NE2   1 
ATOM   1367  N N     . CYS A 1 178 ? -37.100 -7.862  4.970    1.00 34.35  ? 178 CYS A N     1 
ATOM   1368  C CA    . CYS A 1 178 ? -36.864 -7.120  6.195    1.00 34.02  ? 178 CYS A CA    1 
ATOM   1369  C C     . CYS A 1 178 ? -35.878 -7.884  7.069    1.00 35.62  ? 178 CYS A C     1 
ATOM   1370  O O     . CYS A 1 178 ? -36.249 -8.853  7.724    1.00 29.05  ? 178 CYS A O     1 
ATOM   1371  C CB    . CYS A 1 178 ? -38.167 -6.868  6.946    1.00 35.00  ? 178 CYS A CB    1 
ATOM   1372  S SG    . CYS A 1 178 ? -37.978 -5.678  8.304    1.00 36.33  ? 178 CYS A SG    1 
ATOM   1373  N N     . GLY A 1 179 ? -34.620 -7.416  7.085    1.00 43.06  ? 179 GLY A N     1 
ATOM   1374  C CA    . GLY A 1 179 ? -33.592 -8.029  7.921    1.00 42.21  ? 179 GLY A CA    1 
ATOM   1375  C C     . GLY A 1 179 ? -32.850 -9.131  7.169    1.00 39.62  ? 179 GLY A C     1 
ATOM   1376  O O     . GLY A 1 179 ? -33.485 -9.935  6.495    1.00 31.91  ? 179 GLY A O     1 
ATOM   1377  N N     . MET A 1 180 ? -31.509 -9.144  7.268    1.00 39.32  ? 180 MET A N     1 
ATOM   1378  C CA    . MET A 1 180 ? -30.745 -10.243 6.723    1.00 38.44  ? 180 MET A CA    1 
ATOM   1379  C C     . MET A 1 180 ? -29.472 -10.469 7.529    1.00 39.67  ? 180 MET A C     1 
ATOM   1380  O O     . MET A 1 180 ? -28.918 -9.558  8.156    1.00 40.14  ? 180 MET A O     1 
ATOM   1381  C CB    . MET A 1 180 ? -30.407 -10.042 5.238    1.00 36.67  ? 180 MET A CB    1 
ATOM   1382  C CG    . MET A 1 180 ? -29.579 -8.839  4.920    1.00 37.73  ? 180 MET A CG    1 
ATOM   1383  S SD    . MET A 1 180 ? -29.052 -8.708  3.136    1.00 40.06  ? 180 MET A SD    1 
ATOM   1384  C CE    . MET A 1 180 ? -30.602 -8.433  2.282    1.00 40.88  ? 180 MET A CE    1 
ATOM   1385  N N     . GLU A 1 181 ? -29.022 -11.730 7.494    1.00 40.20  ? 181 GLU A N     1 
ATOM   1386  C CA    . GLU A 1 181 ? -27.706 -12.087 7.991    1.00 35.36  ? 181 GLU A CA    1 
ATOM   1387  C C     . GLU A 1 181 ? -26.876 -12.325 6.758    1.00 34.13  ? 181 GLU A C     1 
ATOM   1388  O O     . GLU A 1 181 ? -27.397 -12.979 5.866    1.00 36.48  ? 181 GLU A O     1 
ATOM   1389  C CB    . GLU A 1 181 ? -27.755 -13.342 8.858    1.00 34.41  ? 181 GLU A CB    1 
ATOM   1390  C CG    . GLU A 1 181 ? -26.413 -13.743 9.478    1.00 37.88  ? 181 GLU A CG    1 
ATOM   1391  C CD    . GLU A 1 181 ? -26.523 -14.981 10.373   1.00 45.81  ? 181 GLU A CD    1 
ATOM   1392  O OE1   . GLU A 1 181 ? -26.503 -14.824 11.643   1.00 40.10  ? 181 GLU A OE1   1 
ATOM   1393  O OE2   . GLU A 1 181 ? -26.696 -16.116 9.805    1.00 43.35  ? 181 GLU A OE2   1 
ATOM   1394  N N     . VAL A 1 182 ? -25.621 -11.842 6.761    1.00 31.94  ? 182 VAL A N     1 
ATOM   1395  C CA    . VAL A 1 182 ? -24.765 -11.879 5.593    1.00 33.24  ? 182 VAL A CA    1 
ATOM   1396  C C     . VAL A 1 182 ? -23.349 -12.299 5.968    1.00 37.43  ? 182 VAL A C     1 
ATOM   1397  O O     . VAL A 1 182 ? -22.762 -11.786 6.915    1.00 37.65  ? 182 VAL A O     1 
ATOM   1398  C CB    . VAL A 1 182 ? -24.752 -10.502 4.907    1.00 36.91  ? 182 VAL A CB    1 
ATOM   1399  C CG1   . VAL A 1 182 ? -23.939 -10.515 3.625    1.00 37.87  ? 182 VAL A CG1   1 
ATOM   1400  C CG2   . VAL A 1 182 ? -26.167 -10.020 4.625    1.00 41.51  ? 182 VAL A CG2   1 
ATOM   1401  N N     . VAL A 1 183 ? -22.779 -13.228 5.206    1.00 37.87  ? 183 VAL A N     1 
ATOM   1402  C CA    . VAL A 1 183 ? -21.366 -13.489 5.371    1.00 38.99  ? 183 VAL A CA    1 
ATOM   1403  C C     . VAL A 1 183 ? -20.655 -12.638 4.331    1.00 35.22  ? 183 VAL A C     1 
ATOM   1404  O O     . VAL A 1 183 ? -20.842 -12.824 3.142    1.00 31.78  ? 183 VAL A O     1 
ATOM   1405  C CB    . VAL A 1 183 ? -21.006 -14.984 5.242    1.00 41.43  ? 183 VAL A CB    1 
ATOM   1406  C CG1   . VAL A 1 183 ? -19.499 -15.189 5.187    1.00 39.59  ? 183 VAL A CG1   1 
ATOM   1407  C CG2   . VAL A 1 183 ? -21.610 -15.837 6.353    1.00 40.38  ? 183 VAL A CG2   1 
ATOM   1408  N N     . LEU A 1 184 ? -19.810 -11.728 4.794    1.00 37.12  ? 184 LEU A N     1 
ATOM   1409  C CA    . LEU A 1 184 ? -19.092 -10.844 3.900    1.00 42.22  ? 184 LEU A CA    1 
ATOM   1410  C C     . LEU A 1 184 ? -18.035 -11.638 3.133    1.00 40.99  ? 184 LEU A C     1 
ATOM   1411  O O     . LEU A 1 184 ? -17.663 -12.725 3.516    1.00 42.55  ? 184 LEU A O     1 
ATOM   1412  C CB    . LEU A 1 184 ? -18.474 -9.702  4.716    1.00 41.54  ? 184 LEU A CB    1 
ATOM   1413  C CG    . LEU A 1 184 ? -19.469 -8.769  5.409    1.00 44.46  ? 184 LEU A CG    1 
ATOM   1414  C CD1   . LEU A 1 184 ? -18.753 -7.735  6.285    1.00 41.48  ? 184 LEU A CD1   1 
ATOM   1415  C CD2   . LEU A 1 184 ? -20.350 -8.063  4.387    1.00 42.36  ? 184 LEU A CD2   1 
ATOM   1416  N N     . PRO A 1 185 ? -17.470 -11.100 2.041    1.00 45.64  ? 185 PRO A N     1 
ATOM   1417  C CA    . PRO A 1 185 ? -16.438 -11.825 1.293    1.00 50.03  ? 185 PRO A CA    1 
ATOM   1418  C C     . PRO A 1 185 ? -15.139 -12.101 2.057    1.00 45.72  ? 185 PRO A C     1 
ATOM   1419  O O     . PRO A 1 185 ? -14.377 -12.964 1.633    1.00 52.15  ? 185 PRO A O     1 
ATOM   1420  C CB    . PRO A 1 185 ? -16.175 -10.928 0.066    1.00 44.92  ? 185 PRO A CB    1 
ATOM   1421  C CG    . PRO A 1 185 ? -17.421 -10.040 0.006    1.00 48.27  ? 185 PRO A CG    1 
ATOM   1422  C CD    . PRO A 1 185 ? -17.782 -9.784  1.460    1.00 43.72  ? 185 PRO A CD    1 
ATOM   1423  N N     . ASN A 1 186 ? -14.908 -11.424 3.190    1.00 42.78  ? 186 ASN A N     1 
ATOM   1424  C CA    . ASN A 1 186 ? -13.796 -11.754 4.081    1.00 45.33  ? 186 ASN A CA    1 
ATOM   1425  C C     . ASN A 1 186 ? -14.171 -12.877 5.043    1.00 40.04  ? 186 ASN A C     1 
ATOM   1426  O O     . ASN A 1 186 ? -13.321 -13.313 5.797    1.00 44.81  ? 186 ASN A O     1 
ATOM   1427  C CB    . ASN A 1 186 ? -13.273 -10.580 4.917    1.00 42.66  ? 186 ASN A CB    1 
ATOM   1428  C CG    . ASN A 1 186 ? -14.370 -9.910  5.734    1.00 51.17  ? 186 ASN A CG    1 
ATOM   1429  O OD1   . ASN A 1 186 ? -15.434 -10.481 5.947    1.00 48.46  ? 186 ASN A OD1   1 
ATOM   1430  N ND2   . ASN A 1 186 ? -14.134 -8.698  6.212    1.00 49.04  ? 186 ASN A ND2   1 
ATOM   1431  N N     . GLY A 1 187 ? -15.433 -13.314 5.076    1.00 38.48  ? 187 GLY A N     1 
ATOM   1432  C CA    . GLY A 1 187 ? -15.830 -14.349 6.033    1.00 39.34  ? 187 GLY A CA    1 
ATOM   1433  C C     . GLY A 1 187 ? -16.403 -13.841 7.371    1.00 37.83  ? 187 GLY A C     1 
ATOM   1434  O O     . GLY A 1 187 ? -16.729 -14.648 8.227    1.00 39.87  ? 187 GLY A O     1 
ATOM   1435  N N     . GLU A 1 188 ? -16.560 -12.525 7.574    1.00 37.37  ? 188 GLU A N     1 
ATOM   1436  C CA    . GLU A 1 188 ? -17.190 -12.013 8.785    1.00 42.83  ? 188 GLU A CA    1 
ATOM   1437  C C     . GLU A 1 188 ? -18.707 -12.096 8.637    1.00 42.67  ? 188 GLU A C     1 
ATOM   1438  O O     . GLU A 1 188 ? -19.214 -12.044 7.523    1.00 38.87  ? 188 GLU A O     1 
ATOM   1439  C CB    . GLU A 1 188 ? -16.849 -10.541 9.034    1.00 45.00  ? 188 GLU A CB    1 
ATOM   1440  C CG    . GLU A 1 188 ? -15.361 -10.266 9.205    1.00 49.32  ? 188 GLU A CG    1 
ATOM   1441  C CD    . GLU A 1 188 ? -14.739 -10.698 10.521   1.00 52.83  ? 188 GLU A CD    1 
ATOM   1442  O OE1   . GLU A 1 188 ? -15.239 -10.263 11.572   1.00 58.54  ? 188 GLU A OE1   1 
ATOM   1443  O OE2   . GLU A 1 188 ? -13.740 -11.458 10.490   1.00 62.75  ? 188 GLU A OE2   1 
ATOM   1444  N N     . VAL A 1 189 ? -19.433 -12.183 9.760    1.00 39.13  ? 189 VAL A N     1 
ATOM   1445  C CA    . VAL A 1 189 ? -20.885 -12.285 9.693    1.00 38.34  ? 189 VAL A CA    1 
ATOM   1446  C C     . VAL A 1 189 ? -21.493 -11.000 10.261   1.00 39.35  ? 189 VAL A C     1 
ATOM   1447  O O     . VAL A 1 189 ? -20.952 -10.475 11.224   1.00 41.10  ? 189 VAL A O     1 
ATOM   1448  C CB    . VAL A 1 189 ? -21.359 -13.566 10.381   1.00 35.93  ? 189 VAL A CB    1 
ATOM   1449  C CG1   . VAL A 1 189 ? -21.077 -13.544 11.857   1.00 41.14  ? 189 VAL A CG1   1 
ATOM   1450  C CG2   . VAL A 1 189 ? -22.816 -13.823 10.111   1.00 45.41  ? 189 VAL A CG2   1 
ATOM   1451  N N     . VAL A 1 190 ? -22.473 -10.414 9.545    1.00 37.15  ? 190 VAL A N     1 
ATOM   1452  C CA    . VAL A 1 190 ? -23.198 -9.226  9.979    1.00 38.20  ? 190 VAL A CA    1 
ATOM   1453  C C     . VAL A 1 190 ? -24.697 -9.507  9.912    1.00 37.26  ? 190 VAL A C     1 
ATOM   1454  O O     . VAL A 1 190 ? -25.162 -10.305 9.104    1.00 37.27  ? 190 VAL A O     1 
ATOM   1455  C CB    . VAL A 1 190 ? -22.899 -7.961  9.151    1.00 37.30  ? 190 VAL A CB    1 
ATOM   1456  C CG1   . VAL A 1 190 ? -21.458 -7.533  9.285    1.00 45.43  ? 190 VAL A CG1   1 
ATOM   1457  C CG2   . VAL A 1 190 ? -23.242 -8.125  7.687    1.00 39.81  ? 190 VAL A CG2   1 
ATOM   1458  N N     . ARG A 1 191 ? -25.456 -8.761  10.710   1.00 36.92  ? 191 ARG A N     1 
ATOM   1459  C CA    . ARG A 1 191 ? -26.897 -8.676  10.540   1.00 36.62  ? 191 ARG A CA    1 
ATOM   1460  C C     . ARG A 1 191 ? -27.266 -7.212  10.370   1.00 33.83  ? 191 ARG A C     1 
ATOM   1461  O O     . ARG A 1 191 ? -26.721 -6.338  11.036   1.00 34.44  ? 191 ARG A O     1 
ATOM   1462  C CB    . ARG A 1 191 ? -27.625 -9.284  11.733   1.00 33.75  ? 191 ARG A CB    1 
ATOM   1463  C CG    . ARG A 1 191 ? -27.210 -10.718 11.996   1.00 34.56  ? 191 ARG A CG    1 
ATOM   1464  C CD    . ARG A 1 191 ? -27.750 -11.237 13.300   1.00 34.81  ? 191 ARG A CD    1 
ATOM   1465  N NE    . ARG A 1 191 ? -27.514 -12.667 13.356   1.00 42.14  ? 191 ARG A NE    1 
ATOM   1466  C CZ    . ARG A 1 191 ? -28.095 -13.498 14.217   1.00 41.11  ? 191 ARG A CZ    1 
ATOM   1467  N NH1   . ARG A 1 191 ? -29.016 -13.055 15.043   1.00 35.95  ? 191 ARG A NH1   1 
ATOM   1468  N NH2   . ARG A 1 191 ? -27.787 -14.783 14.212   1.00 44.14  ? 191 ARG A NH2   1 
ATOM   1469  N N     . THR A 1 192 ? -28.172 -6.980  9.439    1.00 30.77  ? 192 THR A N     1 
ATOM   1470  C CA    . THR A 1 192 ? -28.609 -5.646  9.103    1.00 32.68  ? 192 THR A CA    1 
ATOM   1471  C C     . THR A 1 192 ? -29.808 -5.235  9.964    1.00 34.79  ? 192 THR A C     1 
ATOM   1472  O O     . THR A 1 192 ? -30.448 -6.080  10.605   1.00 32.92  ? 192 THR A O     1 
ATOM   1473  C CB    . THR A 1 192 ? -29.009 -5.605  7.629    1.00 30.81  ? 192 THR A CB    1 
ATOM   1474  O OG1   . THR A 1 192 ? -30.283 -6.259  7.512    1.00 24.58  ? 192 THR A OG1   1 
ATOM   1475  C CG2   . THR A 1 192 ? -27.942 -6.234  6.771    1.00 28.30  ? 192 THR A CG2   1 
ATOM   1476  N N     . GLY A 1 193 ? -30.126 -3.927  9.920    1.00 33.16  ? 193 GLY A N     1 
ATOM   1477  C CA    . GLY A 1 193 ? -31.303 -3.414  10.595   1.00 37.12  ? 193 GLY A CA    1 
ATOM   1478  C C     . GLY A 1 193 ? -31.250 -3.724  12.092   1.00 34.66  ? 193 GLY A C     1 
ATOM   1479  O O     . GLY A 1 193 ? -30.179 -3.692  12.684   1.00 31.24  ? 193 GLY A O     1 
ATOM   1480  N N     . MET A 1 194 ? -32.406 -4.043  12.677   1.00 33.43  ? 194 MET A N     1 
ATOM   1481  C CA    . MET A 1 194 ? -32.505 -4.210  14.113   1.00 34.54  ? 194 MET A CA    1 
ATOM   1482  C C     . MET A 1 194 ? -31.788 -5.471  14.559   1.00 36.53  ? 194 MET A C     1 
ATOM   1483  O O     . MET A 1 194 ? -31.528 -5.599  15.759   1.00 39.29  ? 194 MET A O     1 
ATOM   1484  C CB    . MET A 1 194 ? -33.955 -4.331  14.582   1.00 37.07  ? 194 MET A CB    1 
ATOM   1485  C CG    . MET A 1 194 ? -34.828 -3.147  14.208   1.00 40.77  ? 194 MET A CG    1 
ATOM   1486  S SD    . MET A 1 194 ? -34.134 -1.547  14.630   1.00 39.20  ? 194 MET A SD    1 
ATOM   1487  C CE    . MET A 1 194 ? -33.727 -1.764  16.364   1.00 31.94  ? 194 MET A CE    1 
ATOM   1488  N N     . GLY A 1 195 ? -31.488 -6.392  13.628   1.00 31.74  ? 195 GLY A N     1 
ATOM   1489  C CA    . GLY A 1 195 ? -30.806 -7.631  13.992   1.00 34.23  ? 195 GLY A CA    1 
ATOM   1490  C C     . GLY A 1 195 ? -29.377 -7.413  14.499   1.00 37.98  ? 195 GLY A C     1 
ATOM   1491  O O     . GLY A 1 195 ? -28.825 -8.254  15.227   1.00 37.46  ? 195 GLY A O     1 
ATOM   1492  N N     . ALA A 1 196 ? -28.790 -6.261  14.115   1.00 38.21  ? 196 ALA A N     1 
ATOM   1493  C CA    . ALA A 1 196 ? -27.556 -5.760  14.697   1.00 35.47  ? 196 ALA A CA    1 
ATOM   1494  C C     . ALA A 1 196 ? -27.717 -5.421  16.174   1.00 37.35  ? 196 ALA A C     1 
ATOM   1495  O O     . ALA A 1 196 ? -26.736 -5.162  16.870   1.00 36.70  ? 196 ALA A O     1 
ATOM   1496  C CB    . ALA A 1 196 ? -27.086 -4.556  13.941   1.00 35.38  ? 196 ALA A CB    1 
ATOM   1497  N N     . MET A 1 197 ? -28.944 -5.362  16.670   1.00 39.98  ? 197 MET A N     1 
ATOM   1498  C CA    . MET A 1 197 ? -29.102 -4.966  18.058   1.00 42.87  ? 197 MET A CA    1 
ATOM   1499  C C     . MET A 1 197 ? -29.404 -6.216  18.859   1.00 41.33  ? 197 MET A C     1 
ATOM   1500  O O     . MET A 1 197 ? -30.430 -6.853  18.645   1.00 45.49  ? 197 MET A O     1 
ATOM   1501  C CB    . MET A 1 197 ? -30.210 -3.938  18.287   1.00 43.02  ? 197 MET A CB    1 
ATOM   1502  C CG    . MET A 1 197 ? -30.445 -3.745  19.748   1.00 50.33  ? 197 MET A CG    1 
ATOM   1503  S SD    . MET A 1 197 ? -31.849 -2.722  20.117   1.00 46.51  ? 197 MET A SD    1 
ATOM   1504  C CE    . MET A 1 197 ? -31.796 -2.853  21.900   1.00 58.91  ? 197 MET A CE    1 
ATOM   1505  N N     . PRO A 1 198 ? -28.510 -6.610  19.787   1.00 44.10  ? 198 PRO A N     1 
ATOM   1506  C CA    . PRO A 1 198 ? -28.682 -7.854  20.543   1.00 43.79  ? 198 PRO A CA    1 
ATOM   1507  C C     . PRO A 1 198 ? -29.918 -7.740  21.404   1.00 35.54  ? 198 PRO A C     1 
ATOM   1508  O O     . PRO A 1 198 ? -30.190 -6.659  21.891   1.00 49.16  ? 198 PRO A O     1 
ATOM   1509  C CB    . PRO A 1 198 ? -27.436 -7.935  21.424   1.00 46.79  ? 198 PRO A CB    1 
ATOM   1510  C CG    . PRO A 1 198 ? -26.456 -6.975  20.812   1.00 44.58  ? 198 PRO A CG    1 
ATOM   1511  C CD    . PRO A 1 198 ? -27.279 -5.899  20.145   1.00 44.52  ? 198 PRO A CD    1 
ATOM   1512  N N     . GLY A 1 199 ? -30.703 -8.805  21.490   1.00 43.00  ? 199 GLY A N     1 
ATOM   1513  C CA    . GLY A 1 199 ? -31.935 -8.797  22.285   1.00 43.19  ? 199 GLY A CA    1 
ATOM   1514  C C     . GLY A 1 199 ? -33.158 -8.185  21.590   1.00 41.53  ? 199 GLY A C     1 
ATOM   1515  O O     . GLY A 1 199 ? -34.248 -8.147  22.171   1.00 39.60  ? 199 GLY A O     1 
ATOM   1516  N N     . ASN A 1 200 ? -33.014 -7.756  20.329   1.00 40.77  ? 200 ASN A N     1 
ATOM   1517  C CA    . ASN A 1 200 ? -34.152 -7.204  19.607   1.00 38.52  ? 200 ASN A CA    1 
ATOM   1518  C C     . ASN A 1 200 ? -35.202 -8.299  19.402   1.00 41.52  ? 200 ASN A C     1 
ATOM   1519  O O     . ASN A 1 200 ? -34.893 -9.483  19.279   1.00 39.02  ? 200 ASN A O     1 
ATOM   1520  C CB    . ASN A 1 200 ? -33.777 -6.654  18.229   1.00 33.42  ? 200 ASN A CB    1 
ATOM   1521  C CG    . ASN A 1 200 ? -33.593 -7.778  17.234   1.00 34.27  ? 200 ASN A CG    1 
ATOM   1522  O OD1   . ASN A 1 200 ? -34.538 -8.230  16.598   1.00 37.99  ? 200 ASN A OD1   1 
ATOM   1523  N ND2   . ASN A 1 200 ? -32.370 -8.261  17.092   1.00 40.52  ? 200 ASN A ND2   1 
ATOM   1524  N N     . ASN A 1 201 ? -36.461 -7.869  19.301   1.00 42.78  ? 201 ASN A N     1 
ATOM   1525  C CA    . ASN A 1 201 ? -37.537 -8.711  18.824   1.00 35.87  ? 201 ASN A CA    1 
ATOM   1526  C C     . ASN A 1 201 ? -38.139 -8.018  17.606   1.00 32.19  ? 201 ASN A C     1 
ATOM   1527  O O     . ASN A 1 201 ? -39.330 -8.145  17.348   1.00 31.81  ? 201 ASN A O     1 
ATOM   1528  C CB    . ASN A 1 201 ? -38.547 -8.937  19.948   1.00 41.84  ? 201 ASN A CB    1 
ATOM   1529  C CG    . ASN A 1 201 ? -38.082 -9.963  20.955   1.00 43.89  ? 201 ASN A CG    1 
ATOM   1530  O OD1   . ASN A 1 201 ? -37.788 -9.635  22.093   1.00 54.84  ? 201 ASN A OD1   1 
ATOM   1531  N ND2   . ASN A 1 201 ? -37.991 -11.212 20.551   1.00 49.81  ? 201 ASN A ND2   1 
ATOM   1532  N N     . THR A 1 202 ? -37.310 -7.264  16.871   1.00 28.63  ? 202 THR A N     1 
ATOM   1533  C CA    . THR A 1 202 ? -37.814 -6.350  15.866   1.00 32.68  ? 202 THR A CA    1 
ATOM   1534  C C     . THR A 1 202 ? -37.101 -6.507  14.532   1.00 34.02  ? 202 THR A C     1 
ATOM   1535  O O     . THR A 1 202 ? -37.313 -5.680  13.645   1.00 32.71  ? 202 THR A O     1 
ATOM   1536  C CB    . THR A 1 202 ? -37.692 -4.889  16.319   1.00 30.24  ? 202 THR A CB    1 
ATOM   1537  O OG1   . THR A 1 202 ? -36.427 -4.699  16.929   1.00 30.16  ? 202 THR A OG1   1 
ATOM   1538  C CG2   . THR A 1 202 ? -38.751 -4.504  17.320   1.00 31.16  ? 202 THR A CG2   1 
ATOM   1539  N N     . TRP A 1 203 ? -36.318 -7.582  14.371   1.00 37.17  ? 203 TRP A N     1 
ATOM   1540  C CA    . TRP A 1 203 ? -35.529 -7.775  13.158   1.00 38.18  ? 203 TRP A CA    1 
ATOM   1541  C C     . TRP A 1 203 ? -36.395 -7.732  11.895   1.00 36.77  ? 203 TRP A C     1 
ATOM   1542  O O     . TRP A 1 203 ? -35.995 -7.148  10.892   1.00 37.78  ? 203 TRP A O     1 
ATOM   1543  C CB    . TRP A 1 203 ? -34.750 -9.086  13.227   1.00 39.41  ? 203 TRP A CB    1 
ATOM   1544  C CG    . TRP A 1 203 ? -33.567 -9.149  12.317   1.00 34.73  ? 203 TRP A CG    1 
ATOM   1545  C CD1   . TRP A 1 203 ? -33.067 -8.151  11.537   1.00 36.44  ? 203 TRP A CD1   1 
ATOM   1546  C CD2   . TRP A 1 203 ? -32.752 -10.301 12.067   1.00 36.61  ? 203 TRP A CD2   1 
ATOM   1547  N NE1   . TRP A 1 203 ? -31.976 -8.593  10.844   1.00 40.98  ? 203 TRP A NE1   1 
ATOM   1548  C CE2   . TRP A 1 203 ? -31.756 -9.908  11.154   1.00 37.59  ? 203 TRP A CE2   1 
ATOM   1549  C CE3   . TRP A 1 203 ? -32.748 -11.616 12.547   1.00 36.43  ? 203 TRP A CE3   1 
ATOM   1550  C CZ2   . TRP A 1 203 ? -30.777 -10.789 10.706   1.00 36.56  ? 203 TRP A CZ2   1 
ATOM   1551  C CZ3   . TRP A 1 203 ? -31.773 -12.479 12.118   1.00 34.02  ? 203 TRP A CZ3   1 
ATOM   1552  C CH2   . TRP A 1 203 ? -30.798 -12.066 11.216   1.00 36.06  ? 203 TRP A CH2   1 
ATOM   1553  N N     . GLN A 1 204 ? -37.600 -8.312  11.962   1.00 39.22  ? 204 GLN A N     1 
ATOM   1554  C CA    . GLN A 1 204 ? -38.483 -8.442  10.807   1.00 36.85  ? 204 GLN A CA    1 
ATOM   1555  C C     . GLN A 1 204 ? -39.660 -7.457  10.852   1.00 38.25  ? 204 GLN A C     1 
ATOM   1556  O O     . GLN A 1 204 ? -40.708 -7.704  10.218   1.00 32.16  ? 204 GLN A O     1 
ATOM   1557  C CB    . GLN A 1 204 ? -39.053 -9.869  10.802   1.00 37.70  ? 204 GLN A CB    1 
ATOM   1558  C CG    . GLN A 1 204 ? -38.177 -10.873 10.088   1.00 35.69  ? 204 GLN A CG    1 
ATOM   1559  C CD    . GLN A 1 204 ? -36.834 -11.145 10.725   1.00 34.03  ? 204 GLN A CD    1 
ATOM   1560  O OE1   . GLN A 1 204 ? -36.696 -11.879 11.709   1.00 38.61  ? 204 GLN A OE1   1 
ATOM   1561  N NE2   . GLN A 1 204 ? -35.808 -10.625 10.093   1.00 34.87  ? 204 GLN A NE2   1 
ATOM   1562  N N     . LEU A 1 205 ? -39.513 -6.370  11.641   1.00 37.33  ? 205 LEU A N     1 
ATOM   1563  C CA    . LEU A 1 205 ? -40.605 -5.436  11.867   1.00 33.14  ? 205 LEU A CA    1 
ATOM   1564  C C     . LEU A 1 205 ? -40.263 -4.048  11.325   1.00 36.13  ? 205 LEU A C     1 
ATOM   1565  O O     . LEU A 1 205 ? -41.163 -3.282  10.983   1.00 36.20  ? 205 LEU A O     1 
ATOM   1566  C CB    . LEU A 1 205 ? -40.900 -5.365  13.362   1.00 36.32  ? 205 LEU A CB    1 
ATOM   1567  C CG    . LEU A 1 205 ? -41.432 -6.634  14.040   1.00 38.05  ? 205 LEU A CG    1 
ATOM   1568  C CD1   . LEU A 1 205 ? -41.974 -6.302  15.407   1.00 37.14  ? 205 LEU A CD1   1 
ATOM   1569  C CD2   . LEU A 1 205 ? -42.520 -7.315  13.252   1.00 35.87  ? 205 LEU A CD2   1 
ATOM   1570  N N     . PHE A 1 206 ? -38.971 -3.728  11.226   1.00 32.13  ? 206 PHE A N     1 
ATOM   1571  C CA    . PHE A 1 206 ? -38.547 -2.378  10.921   1.00 33.17  ? 206 PHE A CA    1 
ATOM   1572  C C     . PHE A 1 206 ? -37.316 -2.517  10.053   1.00 33.45  ? 206 PHE A C     1 
ATOM   1573  O O     . PHE A 1 206 ? -36.352 -3.110  10.502   1.00 41.01  ? 206 PHE A O     1 
ATOM   1574  C CB    . PHE A 1 206 ? -38.227 -1.598  12.210   1.00 34.13  ? 206 PHE A CB    1 
ATOM   1575  C CG    . PHE A 1 206 ? -37.824 -0.167  11.975   1.00 35.53  ? 206 PHE A CG    1 
ATOM   1576  C CD1   . PHE A 1 206 ? -38.725 0.742   11.441   1.00 34.90  ? 206 PHE A CD1   1 
ATOM   1577  C CD2   . PHE A 1 206 ? -36.528 0.255   12.203   1.00 39.18  ? 206 PHE A CD2   1 
ATOM   1578  C CE1   . PHE A 1 206 ? -38.351 2.051   11.178   1.00 32.83  ? 206 PHE A CE1   1 
ATOM   1579  C CE2   . PHE A 1 206 ? -36.152 1.571   11.943   1.00 38.80  ? 206 PHE A CE2   1 
ATOM   1580  C CZ    . PHE A 1 206 ? -37.057 2.466   11.414   1.00 34.78  ? 206 PHE A CZ    1 
ATOM   1581  N N     . LYS A 1 207 ? -37.376 -2.040  8.814    1.00 31.59  ? 207 LYS A N     1 
ATOM   1582  C CA    . LYS A 1 207 ? -36.341 -2.340  7.841    1.00 34.38  ? 207 LYS A CA    1 
ATOM   1583  C C     . LYS A 1 207 ? -35.006 -1.699  8.195    1.00 37.32  ? 207 LYS A C     1 
ATOM   1584  O O     . LYS A 1 207 ? -33.965 -2.331  8.056    1.00 45.56  ? 207 LYS A O     1 
ATOM   1585  C CB    . LYS A 1 207 ? -36.692 -1.779  6.465    1.00 36.88  ? 207 LYS A CB    1 
ATOM   1586  C CG    . LYS A 1 207 ? -37.711 -2.575  5.673    1.00 41.61  ? 207 LYS A CG    1 
ATOM   1587  C CD    . LYS A 1 207 ? -37.958 -1.918  4.324    1.00 43.31  ? 207 LYS A CD    1 
ATOM   1588  C CE    . LYS A 1 207 ? -38.688 -2.793  3.336    1.00 42.19  ? 207 LYS A CE    1 
ATOM   1589  N NZ    . LYS A 1 207 ? -37.720 -3.498  2.467    1.00 45.65  ? 207 LYS A NZ    1 
ATOM   1590  N N     . TYR A 1 208 ? -35.043 -0.424  8.590    1.00 37.40  ? 208 TYR A N     1 
ATOM   1591  C CA    . TYR A 1 208 ? -33.873 0.427   8.501    1.00 38.25  ? 208 TYR A CA    1 
ATOM   1592  C C     . TYR A 1 208 ? -32.867 0.144   9.600    1.00 36.28  ? 208 TYR A C     1 
ATOM   1593  O O     . TYR A 1 208 ? -31.677 0.188   9.358    1.00 40.83  ? 208 TYR A O     1 
ATOM   1594  C CB    . TYR A 1 208 ? -34.245 1.908   8.594    1.00 39.25  ? 208 TYR A CB    1 
ATOM   1595  C CG    . TYR A 1 208 ? -35.093 2.425   7.460    1.00 42.09  ? 208 TYR A CG    1 
ATOM   1596  C CD1   . TYR A 1 208 ? -34.797 2.152   6.143    1.00 46.42  ? 208 TYR A CD1   1 
ATOM   1597  C CD2   . TYR A 1 208 ? -36.213 3.196   7.711    1.00 49.85  ? 208 TYR A CD2   1 
ATOM   1598  C CE1   . TYR A 1 208 ? -35.600 2.615   5.108    1.00 50.93  ? 208 TYR A CE1   1 
ATOM   1599  C CE2   . TYR A 1 208 ? -36.993 3.714   6.697    1.00 54.55  ? 208 TYR A CE2   1 
ATOM   1600  C CZ    . TYR A 1 208 ? -36.684 3.426   5.385    1.00 52.67  ? 208 TYR A CZ    1 
ATOM   1601  O OH    . TYR A 1 208 ? -37.468 3.960   4.412    1.00 52.49  ? 208 TYR A OH    1 
ATOM   1602  N N     . GLY A 1 209 ? -33.334 -0.071  10.825   1.00 36.54  ? 209 GLY A N     1 
ATOM   1603  C CA    . GLY A 1 209 ? -32.458 0.105   11.969   1.00 38.11  ? 209 GLY A CA    1 
ATOM   1604  C C     . GLY A 1 209 ? -31.942 1.544   12.041   1.00 38.52  ? 209 GLY A C     1 
ATOM   1605  O O     . GLY A 1 209 ? -32.713 2.500   11.989   1.00 38.42  ? 209 GLY A O     1 
ATOM   1606  N N     . TYR A 1 210 ? -30.622 1.682   12.122   1.00 37.52  ? 210 TYR A N     1 
ATOM   1607  C CA    . TYR A 1 210 ? -30.005 2.968   12.313   1.00 36.05  ? 210 TYR A CA    1 
ATOM   1608  C C     . TYR A 1 210 ? -28.783 3.115   11.424   1.00 33.96  ? 210 TYR A C     1 
ATOM   1609  O O     . TYR A 1 210 ? -28.013 2.187   11.284   1.00 38.53  ? 210 TYR A O     1 
ATOM   1610  C CB    . TYR A 1 210 ? -29.549 3.097   13.761   1.00 39.21  ? 210 TYR A CB    1 
ATOM   1611  C CG    . TYR A 1 210 ? -28.806 4.375   14.013   1.00 37.24  ? 210 TYR A CG    1 
ATOM   1612  C CD1   . TYR A 1 210 ? -29.409 5.603   13.786   1.00 36.89  ? 210 TYR A CD1   1 
ATOM   1613  C CD2   . TYR A 1 210 ? -27.491 4.352   14.452   1.00 40.13  ? 210 TYR A CD2   1 
ATOM   1614  C CE1   . TYR A 1 210 ? -28.731 6.784   14.049   1.00 43.73  ? 210 TYR A CE1   1 
ATOM   1615  C CE2   . TYR A 1 210 ? -26.793 5.520   14.716   1.00 41.54  ? 210 TYR A CE2   1 
ATOM   1616  C CZ    . TYR A 1 210 ? -27.420 6.736   14.511   1.00 45.07  ? 210 TYR A CZ    1 
ATOM   1617  O OH    . TYR A 1 210 ? -26.720 7.870   14.765   1.00 50.64  ? 210 TYR A OH    1 
ATOM   1618  N N     . GLY A 1 211 ? -28.595 4.298   10.841   1.00 34.70  ? 211 GLY A N     1 
ATOM   1619  C CA    . GLY A 1 211 ? -27.474 4.535   9.950    1.00 35.12  ? 211 GLY A CA    1 
ATOM   1620  C C     . GLY A 1 211 ? -27.756 4.028   8.538    1.00 35.54  ? 211 GLY A C     1 
ATOM   1621  O O     . GLY A 1 211 ? -28.917 3.828   8.162    1.00 36.88  ? 211 GLY A O     1 
ATOM   1622  N N     . PRO A 1 212 ? -26.697 3.877   7.711    1.00 34.68  ? 212 PRO A N     1 
ATOM   1623  C CA    . PRO A 1 212 ? -26.852 3.621   6.286    1.00 33.27  ? 212 PRO A CA    1 
ATOM   1624  C C     . PRO A 1 212 ? -27.659 2.359   6.072    1.00 33.07  ? 212 PRO A C     1 
ATOM   1625  O O     . PRO A 1 212 ? -27.376 1.349   6.696    1.00 33.12  ? 212 PRO A O     1 
ATOM   1626  C CB    . PRO A 1 212 ? -25.435 3.396   5.745    1.00 34.70  ? 212 PRO A CB    1 
ATOM   1627  C CG    . PRO A 1 212 ? -24.488 3.880   6.841    1.00 36.37  ? 212 PRO A CG    1 
ATOM   1628  C CD    . PRO A 1 212 ? -25.285 3.951   8.119    1.00 36.18  ? 212 PRO A CD    1 
ATOM   1629  N N     . TYR A 1 213 ? -28.654 2.436   5.187    1.00 37.48  ? 213 TYR A N     1 
ATOM   1630  C CA    . TYR A 1 213 ? -29.477 1.277   4.839    1.00 42.86  ? 213 TYR A CA    1 
ATOM   1631  C C     . TYR A 1 213 ? -28.805 0.423   3.757    1.00 39.35  ? 213 TYR A C     1 
ATOM   1632  O O     . TYR A 1 213 ? -28.781 0.856   2.604    1.00 48.59  ? 213 TYR A O     1 
ATOM   1633  C CB    . TYR A 1 213 ? -30.830 1.801   4.351    1.00 42.07  ? 213 TYR A CB    1 
ATOM   1634  C CG    . TYR A 1 213 ? -31.822 0.744   3.990    1.00 42.43  ? 213 TYR A CG    1 
ATOM   1635  C CD1   . TYR A 1 213 ? -31.947 -0.384  4.773    1.00 46.83  ? 213 TYR A CD1   1 
ATOM   1636  C CD2   . TYR A 1 213 ? -32.663 0.885   2.910    1.00 48.38  ? 213 TYR A CD2   1 
ATOM   1637  C CE1   . TYR A 1 213 ? -32.872 -1.361  4.484    1.00 44.28  ? 213 TYR A CE1   1 
ATOM   1638  C CE2   . TYR A 1 213 ? -33.598 -0.089  2.602    1.00 51.58  ? 213 TYR A CE2   1 
ATOM   1639  C CZ    . TYR A 1 213 ? -33.680 -1.223  3.382    1.00 44.96  ? 213 TYR A CZ    1 
ATOM   1640  O OH    . TYR A 1 213 ? -34.563 -2.229  3.161    1.00 53.85  ? 213 TYR A OH    1 
ATOM   1641  N N     . VAL A 1 214 ? -28.332 -0.793  4.098    1.00 34.95  ? 214 VAL A N     1 
ATOM   1642  C CA    . VAL A 1 214 ? -27.398 -1.547  3.255    1.00 34.06  ? 214 VAL A CA    1 
ATOM   1643  C C     . VAL A 1 214 ? -27.964 -2.868  2.720    1.00 34.15  ? 214 VAL A C     1 
ATOM   1644  O O     . VAL A 1 214 ? -27.330 -3.510  1.885    1.00 34.75  ? 214 VAL A O     1 
ATOM   1645  C CB    . VAL A 1 214 ? -26.076 -1.794  4.006    1.00 37.13  ? 214 VAL A CB    1 
ATOM   1646  C CG1   . VAL A 1 214 ? -25.401 -0.491  4.343    1.00 39.05  ? 214 VAL A CG1   1 
ATOM   1647  C CG2   . VAL A 1 214 ? -26.271 -2.601  5.271    1.00 38.97  ? 214 VAL A CG2   1 
ATOM   1648  N N     . ASP A 1 215 ? -29.154 -3.298  3.170    1.00 33.50  ? 215 ASP A N     1 
ATOM   1649  C CA    . ASP A 1 215 ? -29.748 -4.535  2.692    1.00 31.94  ? 215 ASP A CA    1 
ATOM   1650  C C     . ASP A 1 215 ? -29.640 -4.626  1.175    1.00 34.03  ? 215 ASP A C     1 
ATOM   1651  O O     . ASP A 1 215 ? -29.241 -5.650  0.619    1.00 37.78  ? 215 ASP A O     1 
ATOM   1652  C CB    . ASP A 1 215 ? -31.182 -4.673  3.195    1.00 31.74  ? 215 ASP A CB    1 
ATOM   1653  C CG    . ASP A 1 215 ? -31.233 -4.832  4.719    1.00 38.24  ? 215 ASP A CG    1 
ATOM   1654  O OD1   . ASP A 1 215 ? -30.874 -3.837  5.418    1.00 33.95  ? 215 ASP A OD1   1 
ATOM   1655  O OD2   . ASP A 1 215 ? -31.602 -5.966  5.222    1.00 38.56  ? 215 ASP A OD2   1 
ATOM   1656  N N     . GLY A 1 216 ? -30.038 -3.547  0.506    1.00 36.82  ? 216 GLY A N     1 
ATOM   1657  C CA    . GLY A 1 216 ? -30.093 -3.495  -0.942   1.00 35.54  ? 216 GLY A CA    1 
ATOM   1658  C C     . GLY A 1 216 ? -28.759 -3.792  -1.619   1.00 37.11  ? 216 GLY A C     1 
ATOM   1659  O O     . GLY A 1 216 ? -28.807 -4.253  -2.756   1.00 35.12  ? 216 GLY A O     1 
ATOM   1660  N N     . ILE A 1 217 ? -27.602 -3.551  -0.953   1.00 32.23  ? 217 ILE A N     1 
ATOM   1661  C CA    . ILE A 1 217 ? -26.316 -3.764  -1.619   1.00 38.09  ? 217 ILE A CA    1 
ATOM   1662  C C     . ILE A 1 217 ? -25.989 -5.257  -1.791   1.00 39.34  ? 217 ILE A C     1 
ATOM   1663  O O     . ILE A 1 217 ? -25.077 -5.587  -2.553   1.00 39.37  ? 217 ILE A O     1 
ATOM   1664  C CB    . ILE A 1 217 ? -25.134 -3.039  -0.943   1.00 37.19  ? 217 ILE A CB    1 
ATOM   1665  C CG1   . ILE A 1 217 ? -24.699 -3.717  0.354    1.00 36.90  ? 217 ILE A CG1   1 
ATOM   1666  C CG2   . ILE A 1 217 ? -25.426 -1.580  -0.731   1.00 41.33  ? 217 ILE A CG2   1 
ATOM   1667  C CD1   . ILE A 1 217 ? -23.374 -3.241  0.860    1.00 36.16  ? 217 ILE A CD1   1 
ATOM   1668  N N     . PHE A 1 218 ? -26.703 -6.135  -1.072   1.00 36.09  ? 218 PHE A N     1 
ATOM   1669  C CA    . PHE A 1 218 ? -26.570 -7.570  -1.198   1.00 36.29  ? 218 PHE A CA    1 
ATOM   1670  C C     . PHE A 1 218 ? -27.602 -8.185  -2.151   1.00 41.77  ? 218 PHE A C     1 
ATOM   1671  O O     . PHE A 1 218 ? -27.668 -9.422  -2.282   1.00 40.07  ? 218 PHE A O     1 
ATOM   1672  C CB    . PHE A 1 218 ? -26.650 -8.192  0.196    1.00 33.65  ? 218 PHE A CB    1 
ATOM   1673  C CG    . PHE A 1 218 ? -25.587 -7.639  1.084    1.00 35.01  ? 218 PHE A CG    1 
ATOM   1674  C CD1   . PHE A 1 218 ? -24.247 -7.766  0.736    1.00 35.18  ? 218 PHE A CD1   1 
ATOM   1675  C CD2   . PHE A 1 218 ? -25.919 -6.935  2.226    1.00 38.29  ? 218 PHE A CD2   1 
ATOM   1676  C CE1   . PHE A 1 218 ? -23.263 -7.219  1.549    1.00 39.24  ? 218 PHE A CE1   1 
ATOM   1677  C CE2   . PHE A 1 218 ? -24.927 -6.344  3.005    1.00 38.44  ? 218 PHE A CE2   1 
ATOM   1678  C CZ    . PHE A 1 218 ? -23.600 -6.508  2.688    1.00 33.63  ? 218 PHE A CZ    1 
ATOM   1679  N N     . SER A 1 219 ? -28.393 -7.345  -2.836   1.00 38.80  ? 219 SER A N     1 
ATOM   1680  C CA    . SER A 1 219 ? -29.270 -7.858  -3.879   1.00 38.38  ? 219 SER A CA    1 
ATOM   1681  C C     . SER A 1 219 ? -28.607 -7.634  -5.253   1.00 36.23  ? 219 SER A C     1 
ATOM   1682  O O     . SER A 1 219 ? -27.818 -6.712  -5.376   1.00 35.10  ? 219 SER A O     1 
ATOM   1683  C CB    . SER A 1 219 ? -30.679 -7.285  -3.715   1.00 37.66  ? 219 SER A CB    1 
ATOM   1684  O OG    . SER A 1 219 ? -30.768 -5.900  -4.008   1.00 41.36  ? 219 SER A OG    1 
ATOM   1685  N N     . GLN A 1 220 ? -28.867 -8.510  -6.246   1.00 32.99  ? 220 GLN A N     1 
ATOM   1686  C CA    . GLN A 1 220 ? -28.209 -8.526  -7.558   1.00 31.65  ? 220 GLN A CA    1 
ATOM   1687  C C     . GLN A 1 220 ? -26.728 -8.171  -7.453   1.00 35.45  ? 220 GLN A C     1 
ATOM   1688  O O     . GLN A 1 220 ? -26.230 -7.282  -8.154   1.00 31.25  ? 220 GLN A O     1 
ATOM   1689  C CB    . GLN A 1 220 ? -28.866 -7.592  -8.567   1.00 32.32  ? 220 GLN A CB    1 
ATOM   1690  C CG    . GLN A 1 220 ? -30.223 -8.082  -9.054   1.00 39.00  ? 220 GLN A CG    1 
ATOM   1691  C CD    . GLN A 1 220 ? -30.813 -7.379  -10.262  1.00 41.53  ? 220 GLN A CD    1 
ATOM   1692  O OE1   . GLN A 1 220 ? -30.312 -6.363  -10.735  1.00 45.16  ? 220 GLN A OE1   1 
ATOM   1693  N NE2   . GLN A 1 220 ? -31.932 -7.902  -10.754  1.00 41.12  ? 220 GLN A NE2   1 
ATOM   1694  N N     . SER A 1 221 ? -26.016 -8.904  -6.593   1.00 33.02  ? 221 SER A N     1 
ATOM   1695  C CA    . SER A 1 221 ? -24.732 -8.429  -6.132   1.00 37.65  ? 221 SER A CA    1 
ATOM   1696  C C     . SER A 1 221 ? -23.803 -9.605  -5.842   1.00 35.38  ? 221 SER A C     1 
ATOM   1697  O O     . SER A 1 221 ? -24.219 -10.746 -5.692   1.00 38.17  ? 221 SER A O     1 
ATOM   1698  C CB    . SER A 1 221 ? -24.969 -7.528  -4.899   1.00 42.29  ? 221 SER A CB    1 
ATOM   1699  O OG    . SER A 1 221 ? -23.790 -7.282  -4.138   1.00 38.82  ? 221 SER A OG    1 
ATOM   1700  N N     . ASN A 1 222 ? -22.521 -9.290  -5.739   1.00 37.57  ? 222 ASN A N     1 
ATOM   1701  C CA    . ASN A 1 222 ? -21.547 -10.232 -5.233   1.00 37.05  ? 222 ASN A CA    1 
ATOM   1702  C C     . ASN A 1 222 ? -20.766 -9.591  -4.082   1.00 35.14  ? 222 ASN A C     1 
ATOM   1703  O O     . ASN A 1 222 ? -19.566 -9.823  -3.979   1.00 35.85  ? 222 ASN A O     1 
ATOM   1704  C CB    . ASN A 1 222 ? -20.642 -10.709 -6.375   1.00 38.34  ? 222 ASN A CB    1 
ATOM   1705  C CG    . ASN A 1 222 ? -19.964 -9.577  -7.120   1.00 40.08  ? 222 ASN A CG    1 
ATOM   1706  O OD1   . ASN A 1 222 ? -19.942 -8.435  -6.657   1.00 38.15  ? 222 ASN A OD1   1 
ATOM   1707  N ND2   . ASN A 1 222 ? -19.417 -9.886  -8.289   1.00 43.43  ? 222 ASN A ND2   1 
ATOM   1708  N N     . PHE A 1 223 ? -21.439 -8.784  -3.244   1.00 34.31  ? 223 PHE A N     1 
ATOM   1709  C CA    . PHE A 1 223 ? -20.839 -8.181  -2.062   1.00 34.05  ? 223 PHE A CA    1 
ATOM   1710  C C     . PHE A 1 223 ? -21.038 -9.045  -0.824   1.00 33.40  ? 223 PHE A C     1 
ATOM   1711  O O     . PHE A 1 223 ? -20.525 -8.707  0.239    1.00 34.93  ? 223 PHE A O     1 
ATOM   1712  C CB    . PHE A 1 223 ? -21.441 -6.814  -1.761   1.00 37.75  ? 223 PHE A CB    1 
ATOM   1713  C CG    . PHE A 1 223 ? -21.273 -5.807  -2.864   1.00 43.66  ? 223 PHE A CG    1 
ATOM   1714  C CD1   . PHE A 1 223 ? -20.346 -5.999  -3.882   1.00 43.85  ? 223 PHE A CD1   1 
ATOM   1715  C CD2   . PHE A 1 223 ? -22.067 -4.670  -2.901   1.00 40.30  ? 223 PHE A CD2   1 
ATOM   1716  C CE1   . PHE A 1 223 ? -20.201 -5.058  -4.895   1.00 43.31  ? 223 PHE A CE1   1 
ATOM   1717  C CE2   . PHE A 1 223 ? -21.934 -3.744  -3.928   1.00 40.64  ? 223 PHE A CE2   1 
ATOM   1718  C CZ    . PHE A 1 223 ? -21.003 -3.939  -4.922   1.00 43.39  ? 223 PHE A CZ    1 
ATOM   1719  N N     . GLY A 1 224 ? -21.777 -10.152 -0.929   1.00 32.58  ? 224 GLY A N     1 
ATOM   1720  C CA    . GLY A 1 224 ? -21.882 -11.048 0.212    1.00 32.40  ? 224 GLY A CA    1 
ATOM   1721  C C     . GLY A 1 224 ? -22.745 -12.276 -0.061   1.00 37.67  ? 224 GLY A C     1 
ATOM   1722  O O     . GLY A 1 224 ? -23.396 -12.385 -1.093   1.00 47.50  ? 224 GLY A O     1 
ATOM   1723  N N     . VAL A 1 225 ? -22.729 -13.211 0.897    1.00 40.75  ? 225 VAL A N     1 
ATOM   1724  C CA    . VAL A 1 225 ? -23.593 -14.373 0.883    1.00 40.13  ? 225 VAL A CA    1 
ATOM   1725  C C     . VAL A 1 225 ? -24.672 -14.203 1.950    1.00 41.06  ? 225 VAL A C     1 
ATOM   1726  O O     . VAL A 1 225 ? -24.343 -14.202 3.137    1.00 41.88  ? 225 VAL A O     1 
ATOM   1727  C CB    . VAL A 1 225 ? -22.804 -15.662 1.168    1.00 43.61  ? 225 VAL A CB    1 
ATOM   1728  C CG1   . VAL A 1 225 ? -23.699 -16.873 0.942    1.00 41.48  ? 225 VAL A CG1   1 
ATOM   1729  C CG2   . VAL A 1 225 ? -21.528 -15.756 0.349    1.00 41.28  ? 225 VAL A CG2   1 
ATOM   1730  N N     . VAL A 1 226 ? -25.942 -14.127 1.519    1.00 35.44  ? 226 VAL A N     1 
ATOM   1731  C CA    . VAL A 1 226 ? -27.064 -14.074 2.432    1.00 32.78  ? 226 VAL A CA    1 
ATOM   1732  C C     . VAL A 1 226 ? -27.398 -15.479 2.963    1.00 37.46  ? 226 VAL A C     1 
ATOM   1733  O O     . VAL A 1 226 ? -27.718 -16.394 2.183    1.00 36.68  ? 226 VAL A O     1 
ATOM   1734  C CB    . VAL A 1 226 ? -28.270 -13.445 1.722    1.00 31.53  ? 226 VAL A CB    1 
ATOM   1735  C CG1   . VAL A 1 226 ? -29.496 -13.483 2.618    1.00 34.31  ? 226 VAL A CG1   1 
ATOM   1736  C CG2   . VAL A 1 226 ? -27.997 -12.025 1.243    1.00 33.21  ? 226 VAL A CG2   1 
ATOM   1737  N N     . THR A 1 227 ? -27.384 -15.618 4.300    1.00 38.67  ? 227 THR A N     1 
ATOM   1738  C CA    . THR A 1 227 ? -27.603 -16.882 5.005    1.00 40.73  ? 227 THR A CA    1 
ATOM   1739  C C     . THR A 1 227 ? -28.920 -16.906 5.790    1.00 40.48  ? 227 THR A C     1 
ATOM   1740  O O     . THR A 1 227 ? -29.417 -17.968 6.136    1.00 40.16  ? 227 THR A O     1 
ATOM   1741  C CB    . THR A 1 227 ? -26.495 -17.142 6.030    1.00 44.01  ? 227 THR A CB    1 
ATOM   1742  O OG1   . THR A 1 227 ? -26.326 -15.970 6.834    1.00 43.51  ? 227 THR A OG1   1 
ATOM   1743  C CG2   . THR A 1 227 ? -25.166 -17.477 5.396    1.00 43.99  ? 227 THR A CG2   1 
ATOM   1744  N N     . LYS A 1 228 ? -29.479 -15.739 6.115    1.00 41.10  ? 228 LYS A N     1 
ATOM   1745  C CA    . LYS A 1 228 ? -30.837 -15.664 6.634    1.00 41.81  ? 228 LYS A CA    1 
ATOM   1746  C C     . LYS A 1 228 ? -31.487 -14.371 6.137    1.00 42.55  ? 228 LYS A C     1 
ATOM   1747  O O     . LYS A 1 228 ? -30.808 -13.340 5.982    1.00 35.22  ? 228 LYS A O     1 
ATOM   1748  C CB    . LYS A 1 228 ? -30.864 -15.630 8.171    1.00 42.20  ? 228 LYS A CB    1 
ATOM   1749  C CG    . LYS A 1 228 ? -30.185 -16.760 8.920    1.00 40.82  ? 228 LYS A CG    1 
ATOM   1750  C CD    . LYS A 1 228 ? -30.164 -16.487 10.420   1.00 49.10  ? 228 LYS A CD    1 
ATOM   1751  C CE    . LYS A 1 228 ? -29.802 -17.691 11.259   1.00 43.62  ? 228 LYS A CE    1 
ATOM   1752  N NZ    . LYS A 1 228 ? -28.409 -18.087 10.998   1.00 44.71  ? 228 LYS A NZ    1 
ATOM   1753  N N     . MET A 1 229 ? -32.818 -14.415 5.970    1.00 37.83  ? 229 MET A N     1 
ATOM   1754  C CA    . MET A 1 229 ? -33.531 -13.281 5.417    1.00 38.46  ? 229 MET A CA    1 
ATOM   1755  C C     . MET A 1 229 ? -34.975 -13.350 5.876    1.00 37.12  ? 229 MET A C     1 
ATOM   1756  O O     . MET A 1 229 ? -35.581 -14.405 5.846    1.00 31.31  ? 229 MET A O     1 
ATOM   1757  C CB    . MET A 1 229 ? -33.506 -13.275 3.884    1.00 38.54  ? 229 MET A CB    1 
ATOM   1758  C CG    . MET A 1 229 ? -34.029 -11.987 3.273    1.00 40.73  ? 229 MET A CG    1 
ATOM   1759  S SD    . MET A 1 229 ? -34.284 -12.183 1.478    1.00 41.39  ? 229 MET A SD    1 
ATOM   1760  C CE    . MET A 1 229 ? -35.998 -12.713 1.439    1.00 38.70  ? 229 MET A CE    1 
ATOM   1761  N N     . GLY A 1 230 ? -35.490 -12.184 6.283    1.00 39.88  ? 230 GLY A N     1 
ATOM   1762  C CA    . GLY A 1 230 ? -36.873 -12.006 6.683    1.00 35.69  ? 230 GLY A CA    1 
ATOM   1763  C C     . GLY A 1 230 ? -37.688 -11.455 5.528    1.00 32.37  ? 230 GLY A C     1 
ATOM   1764  O O     . GLY A 1 230 ? -37.162 -10.758 4.667    1.00 32.68  ? 230 GLY A O     1 
ATOM   1765  N N     . ILE A 1 231 ? -38.971 -11.804 5.492    1.00 34.11  ? 231 ILE A N     1 
ATOM   1766  C CA    . ILE A 1 231 ? -39.834 -11.278 4.451    1.00 36.28  ? 231 ILE A CA    1 
ATOM   1767  C C     . ILE A 1 231 ? -41.215 -11.106 5.057    1.00 34.71  ? 231 ILE A C     1 
ATOM   1768  O O     . ILE A 1 231 ? -41.665 -11.955 5.807    1.00 42.68  ? 231 ILE A O     1 
ATOM   1769  C CB    . ILE A 1 231 ? -39.867 -12.191 3.197    1.00 36.44  ? 231 ILE A CB    1 
ATOM   1770  C CG1   . ILE A 1 231 ? -40.681 -11.567 2.066    1.00 36.58  ? 231 ILE A CG1   1 
ATOM   1771  C CG2   . ILE A 1 231 ? -40.405 -13.575 3.564    1.00 42.30  ? 231 ILE A CG2   1 
ATOM   1772  C CD1   . ILE A 1 231 ? -40.431 -12.136 0.676    1.00 39.68  ? 231 ILE A CD1   1 
ATOM   1773  N N     . TRP A 1 232 ? -41.874 -10.005 4.708    1.00 38.43  ? 232 TRP A N     1 
ATOM   1774  C CA    . TRP A 1 232 ? -43.200 -9.716  5.199    1.00 32.85  ? 232 TRP A CA    1 
ATOM   1775  C C     . TRP A 1 232 ? -44.190 -10.548 4.414    1.00 34.71  ? 232 TRP A C     1 
ATOM   1776  O O     . TRP A 1 232 ? -43.985 -10.714 3.203    1.00 36.91  ? 232 TRP A O     1 
ATOM   1777  C CB    . TRP A 1 232 ? -43.477 -8.225  5.063    1.00 33.42  ? 232 TRP A CB    1 
ATOM   1778  C CG    . TRP A 1 232 ? -42.694 -7.342  5.982    1.00 34.05  ? 232 TRP A CG    1 
ATOM   1779  C CD1   . TRP A 1 232 ? -42.114 -7.657  7.170    1.00 34.59  ? 232 TRP A CD1   1 
ATOM   1780  C CD2   . TRP A 1 232 ? -42.369 -5.971  5.739    1.00 33.66  ? 232 TRP A CD2   1 
ATOM   1781  N NE1   . TRP A 1 232 ? -41.451 -6.580  7.684    1.00 36.54  ? 232 TRP A NE1   1 
ATOM   1782  C CE2   . TRP A 1 232 ? -41.590 -5.534  6.817    1.00 34.93  ? 232 TRP A CE2   1 
ATOM   1783  C CE3   . TRP A 1 232 ? -42.661 -5.087  4.701    1.00 36.54  ? 232 TRP A CE3   1 
ATOM   1784  C CZ2   . TRP A 1 232 ? -41.120 -4.235  6.907    1.00 39.18  ? 232 TRP A CZ2   1 
ATOM   1785  C CZ3   . TRP A 1 232 ? -42.176 -3.799  4.780    1.00 40.96  ? 232 TRP A CZ3   1 
ATOM   1786  C CH2   . TRP A 1 232 ? -41.420 -3.385  5.870    1.00 41.86  ? 232 TRP A CH2   1 
ATOM   1787  N N     . LEU A 1 233 ? -45.273 -10.955 5.106    1.00 34.50  ? 233 LEU A N     1 
ATOM   1788  C CA    . LEU A 1 233 ? -46.299 -11.857 4.583    1.00 38.77  ? 233 LEU A CA    1 
ATOM   1789  C C     . LEU A 1 233 ? -47.676 -11.235 4.716    1.00 34.63  ? 233 LEU A C     1 
ATOM   1790  O O     . LEU A 1 233 ? -48.009 -10.757 5.787    1.00 34.82  ? 233 LEU A O     1 
ATOM   1791  C CB    . LEU A 1 233 ? -46.273 -13.161 5.393    1.00 39.86  ? 233 LEU A CB    1 
ATOM   1792  C CG    . LEU A 1 233 ? -45.067 -14.048 5.102    1.00 36.48  ? 233 LEU A CG    1 
ATOM   1793  C CD1   . LEU A 1 233 ? -45.075 -15.245 5.999    1.00 35.34  ? 233 LEU A CD1   1 
ATOM   1794  C CD2   . LEU A 1 233 ? -45.065 -14.473 3.638    1.00 36.37  ? 233 LEU A CD2   1 
ATOM   1795  N N     . MET A 1 234 ? -48.474 -11.301 3.644    1.00 34.60  ? 234 MET A N     1 
ATOM   1796  C CA    . MET A 1 234 ? -49.768 -10.644 3.616    1.00 39.28  ? 234 MET A CA    1 
ATOM   1797  C C     . MET A 1 234 ? -50.709 -11.405 4.529    1.00 35.34  ? 234 MET A C     1 
ATOM   1798  O O     . MET A 1 234 ? -50.884 -12.607 4.354    1.00 42.04  ? 234 MET A O     1 
ATOM   1799  C CB    . MET A 1 234 ? -50.335 -10.573 2.190    1.00 40.67  ? 234 MET A CB    1 
ATOM   1800  C CG    . MET A 1 234 ? -51.688 -9.894  2.119    1.00 38.37  ? 234 MET A CG    1 
ATOM   1801  S SD    . MET A 1 234 ? -52.281 -9.412  0.459    1.00 46.81  ? 234 MET A SD    1 
ATOM   1802  C CE    . MET A 1 234 ? -52.141 -10.988 -0.371   1.00 56.91  ? 234 MET A CE    1 
ATOM   1803  N N     . PRO A 1 235 ? -51.323 -10.770 5.556    1.00 44.35  ? 235 PRO A N     1 
ATOM   1804  C CA    . PRO A 1 235 ? -52.437 -11.400 6.290    1.00 43.22  ? 235 PRO A CA    1 
ATOM   1805  C C     . PRO A 1 235 ? -53.476 -11.857 5.283    1.00 39.47  ? 235 PRO A C     1 
ATOM   1806  O O     . PRO A 1 235 ? -53.704 -11.138 4.331    1.00 42.92  ? 235 PRO A O     1 
ATOM   1807  C CB    . PRO A 1 235 ? -53.016 -10.293 7.186    1.00 36.89  ? 235 PRO A CB    1 
ATOM   1808  C CG    . PRO A 1 235 ? -51.822 -9.368  7.382    1.00 42.44  ? 235 PRO A CG    1 
ATOM   1809  C CD    . PRO A 1 235 ? -51.016 -9.432  6.084    1.00 42.89  ? 235 PRO A CD    1 
ATOM   1810  N N     . GLU A 1 236 ? -54.049 -13.048 5.476    1.00 48.25  ? 236 GLU A N     1 
ATOM   1811  C CA    . GLU A 1 236 ? -55.192 -13.500 4.700    1.00 49.83  ? 236 GLU A CA    1 
ATOM   1812  C C     . GLU A 1 236 ? -56.275 -12.428 4.676    1.00 42.41  ? 236 GLU A C     1 
ATOM   1813  O O     . GLU A 1 236 ? -56.727 -12.000 5.721    1.00 41.74  ? 236 GLU A O     1 
ATOM   1814  C CB    . GLU A 1 236 ? -55.771 -14.751 5.341    1.00 62.52  ? 236 GLU A CB    1 
ATOM   1815  C CG    . GLU A 1 236 ? -56.904 -15.371 4.541    1.00 70.46  ? 236 GLU A CG    1 
ATOM   1816  C CD    . GLU A 1 236 ? -57.345 -16.705 5.122    1.00 70.09  ? 236 GLU A CD    1 
ATOM   1817  O OE1   . GLU A 1 236 ? -57.719 -16.750 6.327    1.00 65.65  ? 236 GLU A OE1   1 
ATOM   1818  O OE2   . GLU A 1 236 ? -57.300 -17.686 4.378    1.00 66.75  ? 236 GLU A OE2   1 
ATOM   1819  N N     . PRO A 1 237 ? -56.686 -11.933 3.491    1.00 41.25  ? 237 PRO A N     1 
ATOM   1820  C CA    . PRO A 1 237 ? -57.711 -10.899 3.378    1.00 42.02  ? 237 PRO A CA    1 
ATOM   1821  C C     . PRO A 1 237 ? -59.119 -11.472 3.499    1.00 44.45  ? 237 PRO A C     1 
ATOM   1822  O O     . PRO A 1 237 ? -59.289 -12.689 3.508    1.00 41.32  ? 237 PRO A O     1 
ATOM   1823  C CB    . PRO A 1 237 ? -57.474 -10.376 1.959    1.00 42.64  ? 237 PRO A CB    1 
ATOM   1824  C CG    . PRO A 1 237 ? -57.115 -11.635 1.210    1.00 42.39  ? 237 PRO A CG    1 
ATOM   1825  C CD    . PRO A 1 237 ? -56.199 -12.373 2.170    1.00 43.58  ? 237 PRO A CD    1 
ATOM   1826  N N     . ALA A 1 238 ? -60.117 -10.581 3.560    1.00 48.98  ? 238 ALA A N     1 
ATOM   1827  C CA    . ALA A 1 238 ? -61.485 -10.994 3.855    1.00 46.94  ? 238 ALA A CA    1 
ATOM   1828  C C     . ALA A 1 238 ? -62.251 -11.293 2.575    1.00 47.12  ? 238 ALA A C     1 
ATOM   1829  O O     . ALA A 1 238 ? -63.466 -11.281 2.578    1.00 54.91  ? 238 ALA A O     1 
ATOM   1830  C CB    . ALA A 1 238 ? -62.180 -9.891  4.618    1.00 44.09  ? 238 ALA A CB    1 
ATOM   1831  N N     . GLY A 1 239 ? -61.550 -11.481 1.464    1.00 55.54  ? 239 GLY A N     1 
ATOM   1832  C CA    . GLY A 1 239 ? -62.209 -11.597 0.170    1.00 59.02  ? 239 GLY A CA    1 
ATOM   1833  C C     . GLY A 1 239 ? -61.193 -11.555 -0.967   1.00 50.28  ? 239 GLY A C     1 
ATOM   1834  O O     . GLY A 1 239 ? -60.097 -11.045 -0.794   1.00 48.46  ? 239 GLY A O     1 
ATOM   1835  N N     . TYR A 1 240 ? -61.586 -12.073 -2.125   1.00 48.94  ? 240 TYR A N     1 
ATOM   1836  C CA    . TYR A 1 240 ? -60.657 -12.325 -3.208   1.00 47.03  ? 240 TYR A CA    1 
ATOM   1837  C C     . TYR A 1 240 ? -61.426 -12.637 -4.476   1.00 44.21  ? 240 TYR A C     1 
ATOM   1838  O O     . TYR A 1 240 ? -62.073 -13.663 -4.530   1.00 49.00  ? 240 TYR A O     1 
ATOM   1839  C CB    . TYR A 1 240 ? -59.797 -13.552 -2.908   1.00 47.26  ? 240 TYR A CB    1 
ATOM   1840  C CG    . TYR A 1 240 ? -58.873 -13.911 -4.044   1.00 51.51  ? 240 TYR A CG    1 
ATOM   1841  C CD1   . TYR A 1 240 ? -57.970 -12.986 -4.559   1.00 47.59  ? 240 TYR A CD1   1 
ATOM   1842  C CD2   . TYR A 1 240 ? -58.889 -15.180 -4.595   1.00 47.43  ? 240 TYR A CD2   1 
ATOM   1843  C CE1   . TYR A 1 240 ? -57.115 -13.312 -5.606   1.00 46.05  ? 240 TYR A CE1   1 
ATOM   1844  C CE2   . TYR A 1 240 ? -58.049 -15.516 -5.642   1.00 53.94  ? 240 TYR A CE2   1 
ATOM   1845  C CZ    . TYR A 1 240 ? -57.173 -14.577 -6.166   1.00 50.41  ? 240 TYR A CZ    1 
ATOM   1846  O OH    . TYR A 1 240 ? -56.357 -14.961 -7.210   1.00 42.40  ? 240 TYR A OH    1 
ATOM   1847  N N     . ARG A 1 241 ? -61.325 -11.791 -5.500   1.00 45.09  ? 241 ARG A N     1 
ATOM   1848  C CA    . ARG A 1 241 ? -62.074 -12.012 -6.727   1.00 46.00  ? 241 ARG A CA    1 
ATOM   1849  C C     . ARG A 1 241 ? -61.143 -11.810 -7.913   1.00 42.48  ? 241 ARG A C     1 
ATOM   1850  O O     . ARG A 1 241 ? -60.757 -10.687 -8.215   1.00 39.57  ? 241 ARG A O     1 
ATOM   1851  C CB    . ARG A 1 241 ? -63.254 -11.035 -6.795   1.00 59.14  ? 241 ARG A CB    1 
ATOM   1852  C CG    . ARG A 1 241 ? -64.381 -11.288 -5.803   1.00 62.50  ? 241 ARG A CG    1 
ATOM   1853  C CD    . ARG A 1 241 ? -65.314 -12.368 -6.333   1.00 79.07  ? 241 ARG A CD    1 
ATOM   1854  N NE    . ARG A 1 241 ? -66.138 -11.878 -7.441   1.00 85.98  ? 241 ARG A NE    1 
ATOM   1855  C CZ    . ARG A 1 241 ? -66.780 -12.626 -8.338   1.00 74.07  ? 241 ARG A CZ    1 
ATOM   1856  N NH1   . ARG A 1 241 ? -66.468 -13.897 -8.528   1.00 65.27  ? 241 ARG A NH1   1 
ATOM   1857  N NH2   . ARG A 1 241 ? -67.703 -12.065 -9.097   1.00 78.28  ? 241 ARG A NH2   1 
ATOM   1858  N N     . PRO A 1 242 ? -60.669 -12.878 -8.587   1.00 47.07  ? 242 PRO A N     1 
ATOM   1859  C CA    . PRO A 1 242 ? -59.819 -12.701 -9.770   1.00 39.86  ? 242 PRO A CA    1 
ATOM   1860  C C     . PRO A 1 242 ? -60.681 -12.468 -10.999  1.00 42.37  ? 242 PRO A C     1 
ATOM   1861  O O     . PRO A 1 242 ? -61.848 -12.866 -11.016  1.00 44.89  ? 242 PRO A O     1 
ATOM   1862  C CB    . PRO A 1 242 ? -59.017 -13.994 -9.817   1.00 36.16  ? 242 PRO A CB    1 
ATOM   1863  C CG    . PRO A 1 242 ? -59.917 -15.003 -9.158   1.00 42.28  ? 242 PRO A CG    1 
ATOM   1864  C CD    . PRO A 1 242 ? -60.786 -14.274 -8.164   1.00 41.00  ? 242 PRO A CD    1 
ATOM   1865  N N     . TYR A 1 243 ? -60.119 -11.778 -11.999  1.00 41.38  ? 243 TYR A N     1 
ATOM   1866  C CA    . TYR A 1 243 ? -60.875 -11.459 -13.200  1.00 42.57  ? 243 TYR A CA    1 
ATOM   1867  C C     . TYR A 1 243 ? -60.015 -11.549 -14.462  1.00 44.05  ? 243 TYR A C     1 
ATOM   1868  O O     . TYR A 1 243 ? -58.784 -11.594 -14.436  1.00 38.89  ? 243 TYR A O     1 
ATOM   1869  C CB    . TYR A 1 243 ? -61.551 -10.096 -13.035  1.00 43.99  ? 243 TYR A CB    1 
ATOM   1870  C CG    . TYR A 1 243 ? -60.624 -8.935  -12.773  1.00 47.63  ? 243 TYR A CG    1 
ATOM   1871  C CD1   . TYR A 1 243 ? -59.979 -8.288  -13.814  1.00 44.08  ? 243 TYR A CD1   1 
ATOM   1872  C CD2   . TYR A 1 243 ? -60.381 -8.494  -11.478  1.00 50.49  ? 243 TYR A CD2   1 
ATOM   1873  C CE1   . TYR A 1 243 ? -59.123 -7.230  -13.566  1.00 44.68  ? 243 TYR A CE1   1 
ATOM   1874  C CE2   . TYR A 1 243 ? -59.517 -7.448  -11.213  1.00 48.98  ? 243 TYR A CE2   1 
ATOM   1875  C CZ    . TYR A 1 243 ? -58.901 -6.801  -12.272  1.00 45.38  ? 243 TYR A CZ    1 
ATOM   1876  O OH    . TYR A 1 243 ? -58.064 -5.744  -12.051  1.00 40.49  ? 243 TYR A OH    1 
ATOM   1877  N N     . LEU A 1 244 ? -60.688 -11.569 -15.606  1.00 44.39  ? 244 LEU A N     1 
ATOM   1878  C CA    . LEU A 1 244 ? -59.986 -11.425 -16.865  1.00 42.96  ? 244 LEU A CA    1 
ATOM   1879  C C     . LEU A 1 244 ? -60.773 -10.458 -17.737  1.00 48.18  ? 244 LEU A C     1 
ATOM   1880  O O     . LEU A 1 244 ? -61.989 -10.617 -17.917  1.00 50.62  ? 244 LEU A O     1 
ATOM   1881  C CB    . LEU A 1 244 ? -59.873 -12.800 -17.500  1.00 41.61  ? 244 LEU A CB    1 
ATOM   1882  C CG    . LEU A 1 244 ? -59.413 -12.833 -18.951  1.00 47.27  ? 244 LEU A CG    1 
ATOM   1883  C CD1   . LEU A 1 244 ? -57.975 -12.354 -19.076  1.00 45.77  ? 244 LEU A CD1   1 
ATOM   1884  C CD2   . LEU A 1 244 ? -59.543 -14.250 -19.516  1.00 49.34  ? 244 LEU A CD2   1 
ATOM   1885  N N     . ILE A 1 245 ? -60.071 -9.434  -18.232  1.00 39.74  ? 245 ILE A N     1 
ATOM   1886  C CA    . ILE A 1 245 ? -60.633 -8.567  -19.252  1.00 41.57  ? 245 ILE A CA    1 
ATOM   1887  C C     . ILE A 1 245 ? -59.889 -8.855  -20.560  1.00 38.98  ? 245 ILE A C     1 
ATOM   1888  O O     . ILE A 1 245 ? -58.665 -8.856  -20.551  1.00 41.78  ? 245 ILE A O     1 
ATOM   1889  C CB    . ILE A 1 245 ? -60.511 -7.091  -18.807  1.00 42.86  ? 245 ILE A CB    1 
ATOM   1890  C CG1   . ILE A 1 245 ? -61.064 -6.876  -17.390  1.00 46.50  ? 245 ILE A CG1   1 
ATOM   1891  C CG2   . ILE A 1 245 ? -61.149 -6.169  -19.844  1.00 44.91  ? 245 ILE A CG2   1 
ATOM   1892  C CD1   . ILE A 1 245 ? -60.754 -5.530  -16.772  1.00 45.38  ? 245 ILE A CD1   1 
ATOM   1893  N N     . THR A 1 246 ? -60.599 -9.111  -21.668  1.00 37.98  ? 246 THR A N     1 
ATOM   1894  C CA    . THR A 1 246 ? -59.952 -9.392  -22.955  1.00 38.46  ? 246 THR A CA    1 
ATOM   1895  C C     . THR A 1 246 ? -60.225 -8.248  -23.926  1.00 36.85  ? 246 THR A C     1 
ATOM   1896  O O     . THR A 1 246 ? -61.243 -7.574  -23.788  1.00 35.90  ? 246 THR A O     1 
ATOM   1897  C CB    . THR A 1 246 ? -60.443 -10.722 -23.551  1.00 42.07  ? 246 THR A CB    1 
ATOM   1898  O OG1   . THR A 1 246 ? -61.862 -10.740 -23.756  1.00 40.59  ? 246 THR A OG1   1 
ATOM   1899  C CG2   . THR A 1 246 ? -60.118 -11.909 -22.674  1.00 45.64  ? 246 THR A CG2   1 
ATOM   1900  N N     . PHE A 1 247 ? -59.335 -8.067  -24.914  1.00 39.99  ? 247 PHE A N     1 
ATOM   1901  C CA    . PHE A 1 247 ? -59.495 -7.063  -25.967  1.00 40.00  ? 247 PHE A CA    1 
ATOM   1902  C C     . PHE A 1 247 ? -59.226 -7.677  -27.351  1.00 45.37  ? 247 PHE A C     1 
ATOM   1903  O O     . PHE A 1 247 ? -58.251 -8.427  -27.502  1.00 50.54  ? 247 PHE A O     1 
ATOM   1904  C CB    . PHE A 1 247 ? -58.508 -5.931  -25.714  1.00 38.87  ? 247 PHE A CB    1 
ATOM   1905  C CG    . PHE A 1 247 ? -58.567 -5.349  -24.327  1.00 45.17  ? 247 PHE A CG    1 
ATOM   1906  C CD1   . PHE A 1 247 ? -59.545 -4.434  -23.974  1.00 42.14  ? 247 PHE A CD1   1 
ATOM   1907  C CD2   . PHE A 1 247 ? -57.641 -5.722  -23.359  1.00 46.13  ? 247 PHE A CD2   1 
ATOM   1908  C CE1   . PHE A 1 247 ? -59.592 -3.923  -22.688  1.00 44.39  ? 247 PHE A CE1   1 
ATOM   1909  C CE2   . PHE A 1 247 ? -57.689 -5.190  -22.078  1.00 42.77  ? 247 PHE A CE2   1 
ATOM   1910  C CZ    . PHE A 1 247 ? -58.650 -4.283  -21.750  1.00 41.75  ? 247 PHE A CZ    1 
ATOM   1911  N N     . GLU A 1 248 ? -60.054 -7.313  -28.356  1.00 46.03  ? 248 GLU A N     1 
ATOM   1912  C CA    . GLU A 1 248 ? -60.083 -7.926  -29.689  1.00 47.51  ? 248 GLU A CA    1 
ATOM   1913  C C     . GLU A 1 248 ? -58.889 -7.579  -30.594  1.00 47.75  ? 248 GLU A C     1 
ATOM   1914  O O     . GLU A 1 248 ? -58.451 -8.425  -31.371  1.00 44.73  ? 248 GLU A O     1 
ATOM   1915  C CB    . GLU A 1 248 ? -61.333 -7.508  -30.468  1.00 54.31  ? 248 GLU A CB    1 
ATOM   1916  C CG    . GLU A 1 248 ? -62.573 -8.285  -30.089  1.00 71.14  ? 248 GLU A CG    1 
ATOM   1917  C CD    . GLU A 1 248 ? -62.506 -9.764  -30.452  1.00 84.56  ? 248 GLU A CD    1 
ATOM   1918  O OE1   . GLU A 1 248 ? -62.489 -10.054 -31.669  1.00 87.17  ? 248 GLU A OE1   1 
ATOM   1919  O OE2   . GLU A 1 248 ? -62.456 -10.629 -29.523  1.00 70.02  ? 248 GLU A OE2   1 
ATOM   1920  N N     . ASN A 1 249 ? -58.367 -6.345  -30.551  1.00 48.06  ? 249 ASN A N     1 
ATOM   1921  C CA    . ASN A 1 249 ? -57.403 -5.883  -31.552  1.00 46.34  ? 249 ASN A CA    1 
ATOM   1922  C C     . ASN A 1 249 ? -56.014 -5.650  -30.940  1.00 46.49  ? 249 ASN A C     1 
ATOM   1923  O O     . ASN A 1 249 ? -55.887 -5.336  -29.753  1.00 52.35  ? 249 ASN A O     1 
ATOM   1924  C CB    . ASN A 1 249 ? -57.924 -4.613  -32.212  1.00 47.21  ? 249 ASN A CB    1 
ATOM   1925  C CG    . ASN A 1 249 ? -59.376 -4.779  -32.599  1.00 50.73  ? 249 ASN A CG    1 
ATOM   1926  O OD1   . ASN A 1 249 ? -59.678 -5.529  -33.523  1.00 51.74  ? 249 ASN A OD1   1 
ATOM   1927  N ND2   . ASN A 1 249 ? -60.270 -4.135  -31.858  1.00 46.34  ? 249 ASN A ND2   1 
ATOM   1928  N N     . GLU A 1 250 ? -54.965 -5.800  -31.753  1.00 41.88  ? 250 GLU A N     1 
ATOM   1929  C CA    . GLU A 1 250 ? -53.607 -5.681  -31.240  1.00 46.78  ? 250 GLU A CA    1 
ATOM   1930  C C     . GLU A 1 250 ? -53.333 -4.217  -30.900  1.00 51.78  ? 250 GLU A C     1 
ATOM   1931  O O     . GLU A 1 250 ? -52.619 -3.961  -29.931  1.00 51.12  ? 250 GLU A O     1 
ATOM   1932  C CB    . GLU A 1 250 ? -52.543 -6.271  -32.178  1.00 50.48  ? 250 GLU A CB    1 
ATOM   1933  C CG    . GLU A 1 250 ? -52.767 -5.940  -33.642  1.00 61.03  ? 250 GLU A CG    1 
ATOM   1934  C CD    . GLU A 1 250 ? -51.659 -6.231  -34.643  1.00 62.73  ? 250 GLU A CD    1 
ATOM   1935  O OE1   . GLU A 1 250 ? -50.561 -6.659  -34.255  1.00 74.46  ? 250 GLU A OE1   1 
ATOM   1936  O OE2   . GLU A 1 250 ? -51.906 -5.986  -35.825  1.00 67.18  ? 250 GLU A OE2   1 
ATOM   1937  N N     . ASP A 1 251 ? -53.956 -3.273  -31.634  1.00 50.81  ? 251 ASP A N     1 
ATOM   1938  C CA    . ASP A 1 251 ? -53.782 -1.843  -31.375  1.00 52.76  ? 251 ASP A CA    1 
ATOM   1939  C C     . ASP A 1 251 ? -54.460 -1.408  -30.057  1.00 48.44  ? 251 ASP A C     1 
ATOM   1940  O O     . ASP A 1 251 ? -54.231 -0.295  -29.570  1.00 43.52  ? 251 ASP A O     1 
ATOM   1941  C CB    . ASP A 1 251 ? -54.265 -1.010  -32.575  1.00 57.05  ? 251 ASP A CB    1 
ATOM   1942  C CG    . ASP A 1 251 ? -53.356 -1.023  -33.809  1.00 63.34  ? 251 ASP A CG    1 
ATOM   1943  O OD1   . ASP A 1 251 ? -52.236 -1.578  -33.762  1.00 59.43  ? 251 ASP A OD1   1 
ATOM   1944  O OD2   . ASP A 1 251 ? -53.771 -0.460  -34.826  1.00 65.55  ? 251 ASP A OD2   1 
ATOM   1945  N N     . ASP A 1 252 ? -55.262 -2.291  -29.447  1.00 39.62  ? 252 ASP A N     1 
ATOM   1946  C CA    . ASP A 1 252 ? -55.981 -1.971  -28.233  1.00 41.93  ? 252 ASP A CA    1 
ATOM   1947  C C     . ASP A 1 252 ? -55.003 -1.685  -27.095  1.00 39.73  ? 252 ASP A C     1 
ATOM   1948  O O     . ASP A 1 252 ? -55.332 -0.957  -26.171  1.00 35.94  ? 252 ASP A O     1 
ATOM   1949  C CB    . ASP A 1 252 ? -56.974 -3.080  -27.871  1.00 48.12  ? 252 ASP A CB    1 
ATOM   1950  C CG    . ASP A 1 252 ? -58.282 -3.086  -28.654  1.00 52.01  ? 252 ASP A CG    1 
ATOM   1951  O OD1   . ASP A 1 252 ? -58.642 -2.040  -29.227  1.00 47.44  ? 252 ASP A OD1   1 
ATOM   1952  O OD2   . ASP A 1 252 ? -58.946 -4.145  -28.670  1.00 54.05  ? 252 ASP A OD2   1 
ATOM   1953  N N     . ILE A 1 253 ? -53.758 -2.154  -27.200  1.00 45.06  ? 253 ILE A N     1 
ATOM   1954  C CA    . ILE A 1 253 ? -52.810 -2.019  -26.092  1.00 45.92  ? 253 ILE A CA    1 
ATOM   1955  C C     . ILE A 1 253 ? -52.447 -0.552  -25.829  1.00 43.29  ? 253 ILE A C     1 
ATOM   1956  O O     . ILE A 1 253 ? -52.131 -0.220  -24.687  1.00 49.17  ? 253 ILE A O     1 
ATOM   1957  C CB    . ILE A 1 253 ? -51.596 -2.978  -26.240  1.00 41.18  ? 253 ILE A CB    1 
ATOM   1958  C CG1   . ILE A 1 253 ? -50.806 -3.144  -24.939  1.00 39.17  ? 253 ILE A CG1   1 
ATOM   1959  C CG2   . ILE A 1 253 ? -50.694 -2.603  -27.410  1.00 40.01  ? 253 ILE A CG2   1 
ATOM   1960  C CD1   . ILE A 1 253 ? -51.621 -3.634  -23.758  1.00 36.77  ? 253 ILE A CD1   1 
ATOM   1961  N N     . GLU A 1 254 ? -52.602 0.354   -26.812  1.00 44.13  ? 254 GLU A N     1 
ATOM   1962  C CA    . GLU A 1 254 ? -52.333 1.777   -26.586  1.00 40.25  ? 254 GLU A CA    1 
ATOM   1963  C C     . GLU A 1 254 ? -53.371 2.384   -25.637  1.00 42.62  ? 254 GLU A C     1 
ATOM   1964  O O     . GLU A 1 254 ? -53.026 2.913   -24.591  1.00 46.28  ? 254 GLU A O     1 
ATOM   1965  C CB    . GLU A 1 254 ? -52.273 2.520   -27.914  1.00 44.63  ? 254 GLU A CB    1 
ATOM   1966  C CG    . GLU A 1 254 ? -51.782 3.962   -27.839  1.00 44.48  ? 254 GLU A CG    1 
ATOM   1967  C CD    . GLU A 1 254 ? -51.655 4.648   -29.199  1.00 48.24  ? 254 GLU A CD    1 
ATOM   1968  O OE1   . GLU A 1 254 ? -51.745 3.958   -30.240  1.00 51.61  ? 254 GLU A OE1   1 
ATOM   1969  O OE2   . GLU A 1 254 ? -51.518 5.878   -29.226  1.00 51.35  ? 254 GLU A OE2   1 
ATOM   1970  N N     . THR A 1 255 ? -54.665 2.286   -25.940  1.00 42.61  ? 255 THR A N     1 
ATOM   1971  C CA    . THR A 1 255 ? -55.641 2.880   -25.040  1.00 38.69  ? 255 THR A CA    1 
ATOM   1972  C C     . THR A 1 255 ? -55.653 2.117   -23.699  1.00 42.13  ? 255 THR A C     1 
ATOM   1973  O O     . THR A 1 255 ? -55.772 2.737   -22.644  1.00 39.02  ? 255 THR A O     1 
ATOM   1974  C CB    . THR A 1 255 ? -57.020 2.998   -25.713  1.00 37.77  ? 255 THR A CB    1 
ATOM   1975  O OG1   . THR A 1 255 ? -57.862 3.830   -24.906  1.00 40.73  ? 255 THR A OG1   1 
ATOM   1976  C CG2   . THR A 1 255 ? -57.729 1.670   -25.891  1.00 43.09  ? 255 THR A CG2   1 
ATOM   1977  N N     . VAL A 1 256 ? -55.498 0.778   -23.727  1.00 40.43  ? 256 VAL A N     1 
ATOM   1978  C CA    . VAL A 1 256 ? -55.553 -0.032  -22.518  1.00 41.45  ? 256 VAL A CA    1 
ATOM   1979  C C     . VAL A 1 256 ? -54.472 0.461   -21.546  1.00 40.95  ? 256 VAL A C     1 
ATOM   1980  O O     . VAL A 1 256 ? -54.742 0.650   -20.361  1.00 35.68  ? 256 VAL A O     1 
ATOM   1981  C CB    . VAL A 1 256 ? -55.413 -1.543  -22.830  1.00 43.67  ? 256 VAL A CB    1 
ATOM   1982  C CG1   . VAL A 1 256 ? -55.132 -2.368  -21.583  1.00 40.60  ? 256 VAL A CG1   1 
ATOM   1983  C CG2   . VAL A 1 256 ? -56.634 -2.116  -23.532  1.00 40.14  ? 256 VAL A CG2   1 
ATOM   1984  N N     . THR A 1 257 ? -53.256 0.731   -22.060  1.00 36.84  ? 257 THR A N     1 
ATOM   1985  C CA    . THR A 1 257 ? -52.176 1.179   -21.203  1.00 34.64  ? 257 THR A CA    1 
ATOM   1986  C C     . THR A 1 257 ? -52.460 2.574   -20.648  1.00 37.11  ? 257 THR A C     1 
ATOM   1987  O O     . THR A 1 257 ? -52.200 2.817   -19.485  1.00 42.76  ? 257 THR A O     1 
ATOM   1988  C CB    . THR A 1 257 ? -50.831 1.096   -21.915  1.00 37.63  ? 257 THR A CB    1 
ATOM   1989  O OG1   . THR A 1 257 ? -50.635 -0.251  -22.335  1.00 34.04  ? 257 THR A OG1   1 
ATOM   1990  C CG2   . THR A 1 257 ? -49.693 1.462   -20.992  1.00 41.65  ? 257 THR A CG2   1 
ATOM   1991  N N     . GLU A 1 258 ? -53.051 3.466   -21.441  1.00 35.53  ? 258 GLU A N     1 
ATOM   1992  C CA    . GLU A 1 258 ? -53.475 4.770   -20.954  1.00 38.55  ? 258 GLU A CA    1 
ATOM   1993  C C     . GLU A 1 258 ? -54.412 4.690   -19.753  1.00 39.78  ? 258 GLU A C     1 
ATOM   1994  O O     . GLU A 1 258 ? -54.278 5.468   -18.817  1.00 39.44  ? 258 GLU A O     1 
ATOM   1995  C CB    . GLU A 1 258 ? -54.126 5.570   -22.080  1.00 39.90  ? 258 GLU A CB    1 
ATOM   1996  C CG    . GLU A 1 258 ? -53.074 6.052   -23.103  1.00 47.67  ? 258 GLU A CG    1 
ATOM   1997  C CD    . GLU A 1 258 ? -52.044 7.019   -22.546  1.00 47.77  ? 258 GLU A CD    1 
ATOM   1998  O OE1   . GLU A 1 258 ? -52.492 8.043   -22.001  1.00 48.13  ? 258 GLU A OE1   1 
ATOM   1999  O OE2   . GLU A 1 258 ? -50.813 6.737   -22.622  1.00 49.42  ? 258 GLU A OE2   1 
ATOM   2000  N N     . ARG A 1 259 ? -55.369 3.770   -19.772  1.00 42.66  ? 259 ARG A N     1 
ATOM   2001  C CA    . ARG A 1 259 ? -56.360 3.694   -18.713  1.00 45.23  ? 259 ARG A CA    1 
ATOM   2002  C C     . ARG A 1 259 ? -55.806 3.011   -17.460  1.00 39.15  ? 259 ARG A C     1 
ATOM   2003  O O     . ARG A 1 259 ? -56.314 3.219   -16.377  1.00 42.99  ? 259 ARG A O     1 
ATOM   2004  C CB    . ARG A 1 259 ? -57.589 2.944   -19.228  1.00 47.31  ? 259 ARG A CB    1 
ATOM   2005  C CG    . ARG A 1 259 ? -58.269 3.640   -20.398  1.00 50.13  ? 259 ARG A CG    1 
ATOM   2006  C CD    . ARG A 1 259 ? -58.609 2.607   -21.461  1.00 57.84  ? 259 ARG A CD    1 
ATOM   2007  N NE    . ARG A 1 259 ? -59.131 3.209   -22.677  1.00 58.79  ? 259 ARG A NE    1 
ATOM   2008  C CZ    . ARG A 1 259 ? -60.415 3.487   -22.881  1.00 57.12  ? 259 ARG A CZ    1 
ATOM   2009  N NH1   . ARG A 1 259 ? -61.342 3.187   -21.987  1.00 57.77  ? 259 ARG A NH1   1 
ATOM   2010  N NH2   . ARG A 1 259 ? -60.782 4.018   -24.020  1.00 52.28  ? 259 ARG A NH2   1 
ATOM   2011  N N     . LEU A 1 260 ? -54.804 2.155   -17.598  1.00 39.39  ? 260 LEU A N     1 
ATOM   2012  C CA    . LEU A 1 260 ? -54.207 1.501   -16.436  1.00 43.81  ? 260 LEU A CA    1 
ATOM   2013  C C     . LEU A 1 260 ? -53.389 2.505   -15.618  1.00 41.27  ? 260 LEU A C     1 
ATOM   2014  O O     . LEU A 1 260 ? -53.250 2.347   -14.403  1.00 40.95  ? 260 LEU A O     1 
ATOM   2015  C CB    . LEU A 1 260 ? -53.321 0.322   -16.885  1.00 41.69  ? 260 LEU A CB    1 
ATOM   2016  C CG    . LEU A 1 260 ? -54.067 -0.930  -17.343  1.00 42.09  ? 260 LEU A CG    1 
ATOM   2017  C CD1   . LEU A 1 260 ? -53.110 -1.925  -17.961  1.00 42.77  ? 260 LEU A CD1   1 
ATOM   2018  C CD2   . LEU A 1 260 ? -54.841 -1.566  -16.190  1.00 43.80  ? 260 LEU A CD2   1 
ATOM   2019  N N     . ARG A 1 261 ? -52.801 3.502   -16.287  1.00 35.34  ? 261 ARG A N     1 
ATOM   2020  C CA    . ARG A 1 261 ? -51.944 4.451   -15.594  1.00 40.46  ? 261 ARG A CA    1 
ATOM   2021  C C     . ARG A 1 261 ? -52.618 4.986   -14.336  1.00 35.84  ? 261 ARG A C     1 
ATOM   2022  O O     . ARG A 1 261 ? -52.198 4.649   -13.242  1.00 34.97  ? 261 ARG A O     1 
ATOM   2023  C CB    . ARG A 1 261 ? -51.532 5.629   -16.472  1.00 41.70  ? 261 ARG A CB    1 
ATOM   2024  C CG    . ARG A 1 261 ? -50.529 6.527   -15.772  1.00 42.66  ? 261 ARG A CG    1 
ATOM   2025  C CD    . ARG A 1 261 ? -50.072 7.671   -16.647  1.00 38.20  ? 261 ARG A CD    1 
ATOM   2026  N NE    . ARG A 1 261 ? -51.122 8.158   -17.510  1.00 35.61  ? 261 ARG A NE    1 
ATOM   2027  C CZ    . ARG A 1 261 ? -51.116 8.077   -18.840  1.00 37.59  ? 261 ARG A CZ    1 
ATOM   2028  N NH1   . ARG A 1 261 ? -50.212 7.373   -19.487  1.00 42.43  ? 261 ARG A NH1   1 
ATOM   2029  N NH2   . ARG A 1 261 ? -52.057 8.672   -19.536  1.00 36.34  ? 261 ARG A NH2   1 
ATOM   2030  N N     . PRO A 1 262 ? -53.725 5.753   -14.418  1.00 36.76  ? 262 PRO A N     1 
ATOM   2031  C CA    . PRO A 1 262 ? -54.339 6.307   -13.214  1.00 36.19  ? 262 PRO A CA    1 
ATOM   2032  C C     . PRO A 1 262 ? -54.732 5.238   -12.192  1.00 36.88  ? 262 PRO A C     1 
ATOM   2033  O O     . PRO A 1 262 ? -54.626 5.487   -10.994  1.00 46.68  ? 262 PRO A O     1 
ATOM   2034  C CB    . PRO A 1 262 ? -55.490 7.165   -13.754  1.00 32.33  ? 262 PRO A CB    1 
ATOM   2035  C CG    . PRO A 1 262 ? -55.840 6.486   -15.057  1.00 34.54  ? 262 PRO A CG    1 
ATOM   2036  C CD    . PRO A 1 262 ? -54.496 6.081   -15.629  1.00 38.74  ? 262 PRO A CD    1 
ATOM   2037  N N     . LEU A 1 263 ? -55.072 4.022   -12.635  1.00 39.50  ? 263 LEU A N     1 
ATOM   2038  C CA    . LEU A 1 263 ? -55.553 2.980   -11.723  1.00 37.03  ? 263 LEU A CA    1 
ATOM   2039  C C     . LEU A 1 263 ? -54.401 2.413   -10.891  1.00 32.97  ? 263 LEU A C     1 
ATOM   2040  O O     . LEU A 1 263 ? -54.528 2.084   -9.709   1.00 36.50  ? 263 LEU A O     1 
ATOM   2041  C CB    . LEU A 1 263 ? -56.214 1.880   -12.564  1.00 38.95  ? 263 LEU A CB    1 
ATOM   2042  C CG    . LEU A 1 263 ? -57.562 2.212   -13.204  1.00 41.28  ? 263 LEU A CG    1 
ATOM   2043  C CD1   . LEU A 1 263 ? -58.065 1.045   -14.063  1.00 41.06  ? 263 LEU A CD1   1 
ATOM   2044  C CD2   . LEU A 1 263 ? -58.588 2.533   -12.131  1.00 38.14  ? 263 LEU A CD2   1 
ATOM   2045  N N     . LYS A 1 264 ? -53.258 2.303   -11.529  1.00 32.21  ? 264 LYS A N     1 
ATOM   2046  C CA    . LYS A 1 264 ? -52.069 1.735   -10.921  1.00 37.60  ? 264 LYS A CA    1 
ATOM   2047  C C     . LYS A 1 264 ? -51.361 2.748   -10.010  1.00 39.25  ? 264 LYS A C     1 
ATOM   2048  O O     . LYS A 1 264 ? -51.055 2.438   -8.867   1.00 43.41  ? 264 LYS A O     1 
ATOM   2049  C CB    . LYS A 1 264 ? -51.185 1.264   -12.072  1.00 43.30  ? 264 LYS A CB    1 
ATOM   2050  C CG    . LYS A 1 264 ? -50.466 -0.046  -11.847  1.00 44.82  ? 264 LYS A CG    1 
ATOM   2051  C CD    . LYS A 1 264 ? -51.341 -1.190  -11.595  1.00 46.27  ? 264 LYS A CD    1 
ATOM   2052  C CE    . LYS A 1 264 ? -50.594 -2.246  -10.808  1.00 50.72  ? 264 LYS A CE    1 
ATOM   2053  N NZ    . LYS A 1 264 ? -50.257 -1.791  -9.435   1.00 46.47  ? 264 LYS A NZ    1 
ATOM   2054  N N     . VAL A 1 265 ? -51.112 3.967   -10.508  1.00 42.52  ? 265 VAL A N     1 
ATOM   2055  C CA    . VAL A 1 265 ? -50.477 5.025   -9.748   1.00 40.55  ? 265 VAL A CA    1 
ATOM   2056  C C     . VAL A 1 265 ? -51.247 5.274   -8.446   1.00 41.90  ? 265 VAL A C     1 
ATOM   2057  O O     . VAL A 1 265 ? -50.645 5.520   -7.413   1.00 40.72  ? 265 VAL A O     1 
ATOM   2058  C CB    . VAL A 1 265 ? -50.375 6.302   -10.612  1.00 40.94  ? 265 VAL A CB    1 
ATOM   2059  C CG1   . VAL A 1 265 ? -49.964 7.528   -9.811   1.00 40.65  ? 265 VAL A CG1   1 
ATOM   2060  C CG2   . VAL A 1 265 ? -49.431 6.121   -11.782  1.00 39.01  ? 265 VAL A CG2   1 
ATOM   2061  N N     . ALA A 1 266 ? -52.583 5.226   -8.502   1.00 43.16  ? 266 ALA A N     1 
ATOM   2062  C CA    . ALA A 1 266 ? -53.419 5.509   -7.343   1.00 40.50  ? 266 ALA A CA    1 
ATOM   2063  C C     . ALA A 1 266 ? -53.550 4.279   -6.453   1.00 40.43  ? 266 ALA A C     1 
ATOM   2064  O O     . ALA A 1 266 ? -53.907 4.419   -5.305   1.00 48.75  ? 266 ALA A O     1 
ATOM   2065  C CB    . ALA A 1 266 ? -54.783 5.991   -7.770   1.00 37.42  ? 266 ALA A CB    1 
ATOM   2066  N N     . GLY A 1 267 ? -53.301 3.083   -6.988   1.00 46.04  ? 267 GLY A N     1 
ATOM   2067  C CA    . GLY A 1 267 ? -53.416 1.836   -6.245   1.00 42.59  ? 267 GLY A CA    1 
ATOM   2068  C C     . GLY A 1 267 ? -54.831 1.240   -6.229   1.00 42.33  ? 267 GLY A C     1 
ATOM   2069  O O     . GLY A 1 267 ? -55.127 0.463   -5.341   1.00 42.28  ? 267 GLY A O     1 
ATOM   2070  N N     . VAL A 1 268 ? -55.697 1.588   -7.190   1.00 41.14  ? 268 VAL A N     1 
ATOM   2071  C CA    . VAL A 1 268 ? -57.046 1.032   -7.287   1.00 46.82  ? 268 VAL A CA    1 
ATOM   2072  C C     . VAL A 1 268 ? -56.943 -0.464  -7.636   1.00 47.92  ? 268 VAL A C     1 
ATOM   2073  O O     . VAL A 1 268 ? -57.654 -1.293  -7.089   1.00 48.45  ? 268 VAL A O     1 
ATOM   2074  C CB    . VAL A 1 268 ? -57.884 1.846   -8.318   1.00 47.04  ? 268 VAL A CB    1 
ATOM   2075  C CG1   . VAL A 1 268 ? -59.256 1.250   -8.620   1.00 45.29  ? 268 VAL A CG1   1 
ATOM   2076  C CG2   . VAL A 1 268 ? -58.046 3.292   -7.884   1.00 41.88  ? 268 VAL A CG2   1 
ATOM   2077  N N     . ILE A 1 269 ? -56.062 -0.793  -8.589   1.00 49.19  ? 269 ILE A N     1 
ATOM   2078  C CA    . ILE A 1 269 ? -55.566 -2.140  -8.823   1.00 44.22  ? 269 ILE A CA    1 
ATOM   2079  C C     . ILE A 1 269 ? -54.517 -2.454  -7.760   1.00 39.07  ? 269 ILE A C     1 
ATOM   2080  O O     . ILE A 1 269 ? -53.557 -1.734  -7.621   1.00 43.36  ? 269 ILE A O     1 
ATOM   2081  C CB    . ILE A 1 269 ? -54.996 -2.243  -10.258  1.00 42.43  ? 269 ILE A CB    1 
ATOM   2082  C CG1   . ILE A 1 269 ? -56.096 -2.055  -11.318  1.00 44.05  ? 269 ILE A CG1   1 
ATOM   2083  C CG2   . ILE A 1 269 ? -54.225 -3.537  -10.445  1.00 36.47  ? 269 ILE A CG2   1 
ATOM   2084  C CD1   . ILE A 1 269 ? -55.618 -1.674  -12.724  1.00 39.81  ? 269 ILE A CD1   1 
ATOM   2085  N N     . GLN A 1 270 ? -54.687 -3.547  -7.018   1.00 46.34  ? 270 GLN A N     1 
ATOM   2086  C CA    . GLN A 1 270 ? -53.929 -3.806  -5.803   1.00 40.94  ? 270 GLN A CA    1 
ATOM   2087  C C     . GLN A 1 270 ? -52.714 -4.699  -6.065   1.00 41.52  ? 270 GLN A C     1 
ATOM   2088  O O     . GLN A 1 270 ? -51.803 -4.790  -5.246   1.00 39.41  ? 270 GLN A O     1 
ATOM   2089  C CB    . GLN A 1 270 ? -54.881 -4.471  -4.812   1.00 38.33  ? 270 GLN A CB    1 
ATOM   2090  C CG    . GLN A 1 270 ? -55.974 -3.538  -4.317   1.00 42.26  ? 270 GLN A CG    1 
ATOM   2091  C CD    . GLN A 1 270 ? -57.165 -4.325  -3.827   1.00 46.02  ? 270 GLN A CD    1 
ATOM   2092  O OE1   . GLN A 1 270 ? -57.779 -5.078  -4.583   1.00 47.25  ? 270 GLN A OE1   1 
ATOM   2093  N NE2   . GLN A 1 270 ? -57.489 -4.164  -2.550   1.00 44.51  ? 270 GLN A NE2   1 
ATOM   2094  N N     . ASN A 1 271 ? -52.752 -5.459  -7.160   1.00 44.04  ? 271 ASN A N     1 
ATOM   2095  C CA    . ASN A 1 271 ? -51.621 -6.289  -7.524   1.00 47.35  ? 271 ASN A CA    1 
ATOM   2096  C C     . ASN A 1 271 ? -51.010 -5.706  -8.790   1.00 43.07  ? 271 ASN A C     1 
ATOM   2097  O O     . ASN A 1 271 ? -51.464 -4.679  -9.278   1.00 47.78  ? 271 ASN A O     1 
ATOM   2098  C CB    . ASN A 1 271 ? -51.998 -7.764  -7.641   1.00 46.70  ? 271 ASN A CB    1 
ATOM   2099  C CG    . ASN A 1 271 ? -53.099 -8.019  -8.641   1.00 43.99  ? 271 ASN A CG    1 
ATOM   2100  O OD1   . ASN A 1 271 ? -53.737 -7.093  -9.151   1.00 40.77  ? 271 ASN A OD1   1 
ATOM   2101  N ND2   . ASN A 1 271 ? -53.300 -9.292  -8.932   1.00 43.78  ? 271 ASN A ND2   1 
ATOM   2102  N N     . GLY A 1 272 ? -49.912 -6.296  -9.244   1.00 37.44  ? 272 GLY A N     1 
ATOM   2103  C CA    . GLY A 1 272 ? -49.360 -5.891  -10.516  1.00 39.56  ? 272 GLY A CA    1 
ATOM   2104  C C     . GLY A 1 272 ? -50.415 -6.140  -11.586  1.00 39.20  ? 272 GLY A C     1 
ATOM   2105  O O     . GLY A 1 272 ? -51.131 -7.130  -11.475  1.00 37.98  ? 272 GLY A O     1 
ATOM   2106  N N     . ALA A 1 273 ? -50.554 -5.211  -12.541  1.00 40.01  ? 273 ALA A N     1 
ATOM   2107  C CA    . ALA A 1 273 ? -51.431 -5.413  -13.687  1.00 42.43  ? 273 ALA A CA    1 
ATOM   2108  C C     . ALA A 1 273 ? -50.644 -6.165  -14.736  1.00 42.20  ? 273 ALA A C     1 
ATOM   2109  O O     . ALA A 1 273 ? -49.540 -5.752  -15.036  1.00 48.77  ? 273 ALA A O     1 
ATOM   2110  C CB    . ALA A 1 273 ? -51.931 -4.104  -14.263  1.00 40.94  ? 273 ALA A CB    1 
ATOM   2111  N N     . THR A 1 274 ? -51.220 -7.237  -15.292  1.00 50.49  ? 274 THR A N     1 
ATOM   2112  C CA    . THR A 1 274 ? -50.560 -7.999  -16.341  1.00 46.88  ? 274 THR A CA    1 
ATOM   2113  C C     . THR A 1 274 ? -51.524 -8.104  -17.519  1.00 41.57  ? 274 THR A C     1 
ATOM   2114  O O     . THR A 1 274 ? -52.635 -8.571  -17.345  1.00 49.43  ? 274 THR A O     1 
ATOM   2115  C CB    . THR A 1 274 ? -50.038 -9.313  -15.749  1.00 50.25  ? 274 THR A CB    1 
ATOM   2116  O OG1   . THR A 1 274 ? -51.108 -9.938  -15.050  1.00 63.45  ? 274 THR A OG1   1 
ATOM   2117  C CG2   . THR A 1 274 ? -48.952 -9.108  -14.717  1.00 57.66  ? 274 THR A CG2   1 
ATOM   2118  N N     . VAL A 1 275 ? -51.094 -7.634  -18.692  1.00 37.07  ? 275 VAL A N     1 
ATOM   2119  C CA    . VAL A 1 275 ? -51.830 -7.732  -19.936  1.00 39.31  ? 275 VAL A CA    1 
ATOM   2120  C C     . VAL A 1 275 ? -51.033 -8.604  -20.908  1.00 39.66  ? 275 VAL A C     1 
ATOM   2121  O O     . VAL A 1 275 ? -50.053 -8.143  -21.477  1.00 37.18  ? 275 VAL A O     1 
ATOM   2122  C CB    . VAL A 1 275 ? -52.033 -6.333  -20.544  1.00 42.77  ? 275 VAL A CB    1 
ATOM   2123  C CG1   . VAL A 1 275 ? -52.927 -6.361  -21.779  1.00 43.23  ? 275 VAL A CG1   1 
ATOM   2124  C CG2   . VAL A 1 275 ? -52.558 -5.354  -19.522  1.00 43.44  ? 275 VAL A CG2   1 
ATOM   2125  N N     . ARG A 1 276 ? -51.471 -9.851  -21.122  1.00 40.02  ? 276 ARG A N     1 
ATOM   2126  C CA    . ARG A 1 276 ? -50.659 -10.862 -21.789  1.00 39.11  ? 276 ARG A CA    1 
ATOM   2127  C C     . ARG A 1 276 ? -51.098 -11.025 -23.234  1.00 33.20  ? 276 ARG A C     1 
ATOM   2128  O O     . ARG A 1 276 ? -52.272 -10.939 -23.522  1.00 39.44  ? 276 ARG A O     1 
ATOM   2129  C CB    . ARG A 1 276 ? -50.757 -12.183 -21.033  1.00 41.62  ? 276 ARG A CB    1 
ATOM   2130  C CG    . ARG A 1 276 ? -50.016 -12.171 -19.705  1.00 42.35  ? 276 ARG A CG    1 
ATOM   2131  C CD    . ARG A 1 276 ? -50.354 -13.378 -18.871  1.00 47.59  ? 276 ARG A CD    1 
ATOM   2132  N NE    . ARG A 1 276 ? -49.226 -13.762 -18.058  1.00 54.88  ? 276 ARG A NE    1 
ATOM   2133  C CZ    . ARG A 1 276 ? -49.048 -13.383 -16.803  1.00 67.08  ? 276 ARG A CZ    1 
ATOM   2134  N NH1   . ARG A 1 276 ? -49.932 -12.587 -16.213  1.00 61.37  ? 276 ARG A NH1   1 
ATOM   2135  N NH2   . ARG A 1 276 ? -47.977 -13.811 -16.151  1.00 78.34  ? 276 ARG A NH2   1 
ATOM   2136  N N     . SER A 1 277 ? -50.157 -11.174 -24.155  1.00 38.11  ? 277 SER A N     1 
ATOM   2137  C CA    . SER A 1 277 ? -50.521 -11.392 -25.555  1.00 45.65  ? 277 SER A CA    1 
ATOM   2138  C C     . SER A 1 277 ? -51.236 -12.734 -25.707  1.00 43.19  ? 277 SER A C     1 
ATOM   2139  O O     . SER A 1 277 ? -51.167 -13.609 -24.832  1.00 42.89  ? 277 SER A O     1 
ATOM   2140  C CB    . SER A 1 277 ? -49.316 -11.374 -26.458  1.00 39.95  ? 277 SER A CB    1 
ATOM   2141  O OG    . SER A 1 277 ? -48.553 -12.552 -26.268  1.00 38.63  ? 277 SER A OG    1 
ATOM   2142  N N     . LEU A 1 278 ? -51.882 -12.895 -26.860  1.00 42.57  ? 278 LEU A N     1 
ATOM   2143  C CA    . LEU A 1 278 ? -52.665 -14.086 -27.167  1.00 42.72  ? 278 LEU A CA    1 
ATOM   2144  C C     . LEU A 1 278 ? -51.856 -15.378 -27.039  1.00 41.70  ? 278 LEU A C     1 
ATOM   2145  O O     . LEU A 1 278 ? -52.275 -16.286 -26.353  1.00 40.20  ? 278 LEU A O     1 
ATOM   2146  C CB    . LEU A 1 278 ? -53.228 -13.946 -28.572  1.00 41.89  ? 278 LEU A CB    1 
ATOM   2147  C CG    . LEU A 1 278 ? -53.852 -15.210 -29.140  1.00 45.67  ? 278 LEU A CG    1 
ATOM   2148  C CD1   . LEU A 1 278 ? -54.963 -15.715 -28.221  1.00 44.33  ? 278 LEU A CD1   1 
ATOM   2149  C CD2   . LEU A 1 278 ? -54.344 -14.911 -30.544  1.00 43.59  ? 278 LEU A CD2   1 
ATOM   2150  N N     . VAL A 1 279 ? -50.691 -15.475 -27.681  1.00 43.26  ? 279 VAL A N     1 
ATOM   2151  C CA    . VAL A 1 279 ? -49.975 -16.736 -27.701  1.00 40.25  ? 279 VAL A CA    1 
ATOM   2152  C C     . VAL A 1 279 ? -49.445 -17.059 -26.312  1.00 42.68  ? 279 VAL A C     1 
ATOM   2153  O O     . VAL A 1 279 ? -49.318 -18.233 -25.948  1.00 44.24  ? 279 VAL A O     1 
ATOM   2154  C CB    . VAL A 1 279 ? -48.850 -16.746 -28.751  1.00 41.33  ? 279 VAL A CB    1 
ATOM   2155  C CG1   . VAL A 1 279 ? -47.989 -18.007 -28.670  1.00 42.63  ? 279 VAL A CG1   1 
ATOM   2156  C CG2   . VAL A 1 279 ? -49.408 -16.592 -30.162  1.00 38.20  ? 279 VAL A CG2   1 
ATOM   2157  N N     . LEU A 1 280 ? -49.084 -16.032 -25.540  1.00 49.11  ? 280 LEU A N     1 
ATOM   2158  C CA    . LEU A 1 280 ? -48.506 -16.312 -24.237  1.00 43.30  ? 280 LEU A CA    1 
ATOM   2159  C C     . LEU A 1 280 ? -49.569 -16.956 -23.346  1.00 41.09  ? 280 LEU A C     1 
ATOM   2160  O O     . LEU A 1 280 ? -49.246 -17.914 -22.632  1.00 39.02  ? 280 LEU A O     1 
ATOM   2161  C CB    . LEU A 1 280 ? -47.904 -15.062 -23.602  1.00 41.51  ? 280 LEU A CB    1 
ATOM   2162  C CG    . LEU A 1 280 ? -47.285 -15.310 -22.224  1.00 41.78  ? 280 LEU A CG    1 
ATOM   2163  C CD1   . LEU A 1 280 ? -46.206 -16.375 -22.304  1.00 39.41  ? 280 LEU A CD1   1 
ATOM   2164  C CD2   . LEU A 1 280 ? -46.718 -14.022 -21.631  1.00 39.40  ? 280 LEU A CD2   1 
ATOM   2165  N N     . ASP A 1 281 ? -50.832 -16.508 -23.470  1.00 41.22  ? 281 ASP A N     1 
ATOM   2166  C CA    . ASP A 1 281 ? -51.932 -17.076 -22.684  1.00 43.91  ? 281 ASP A CA    1 
ATOM   2167  C C     . ASP A 1 281 ? -52.374 -18.442 -23.222  1.00 46.35  ? 281 ASP A C     1 
ATOM   2168  O O     . ASP A 1 281 ? -52.430 -19.410 -22.453  1.00 50.89  ? 281 ASP A O     1 
ATOM   2169  C CB    . ASP A 1 281 ? -53.087 -16.075 -22.536  1.00 44.62  ? 281 ASP A CB    1 
ATOM   2170  C CG    . ASP A 1 281 ? -52.895 -15.174 -21.319  1.00 46.79  ? 281 ASP A CG    1 
ATOM   2171  O OD1   . ASP A 1 281 ? -51.909 -15.397 -20.590  1.00 47.13  ? 281 ASP A OD1   1 
ATOM   2172  O OD2   . ASP A 1 281 ? -53.734 -14.265 -21.091  1.00 48.09  ? 281 ASP A OD2   1 
ATOM   2173  N N     . ALA A 1 282 ? -52.633 -18.540 -24.537  1.00 41.59  ? 282 ALA A N     1 
ATOM   2174  C CA    . ALA A 1 282 ? -53.016 -19.793 -25.189  1.00 43.81  ? 282 ALA A CA    1 
ATOM   2175  C C     . ALA A 1 282 ? -52.068 -20.945 -24.850  1.00 44.49  ? 282 ALA A C     1 
ATOM   2176  O O     . ALA A 1 282 ? -52.512 -22.086 -24.699  1.00 47.97  ? 282 ALA A O     1 
ATOM   2177  C CB    . ALA A 1 282 ? -53.050 -19.613 -26.691  1.00 42.36  ? 282 ALA A CB    1 
ATOM   2178  N N     . ALA A 1 283 ? -50.759 -20.657 -24.799  1.00 42.70  ? 283 ALA A N     1 
ATOM   2179  C CA    . ALA A 1 283 ? -49.741 -21.687 -24.671  1.00 41.76  ? 283 ALA A CA    1 
ATOM   2180  C C     . ALA A 1 283 ? -49.773 -22.359 -23.296  1.00 44.55  ? 283 ALA A C     1 
ATOM   2181  O O     . ALA A 1 283 ? -49.053 -23.335 -23.088  1.00 41.90  ? 283 ALA A O     1 
ATOM   2182  C CB    . ALA A 1 283 ? -48.390 -21.095 -24.956  1.00 42.07  ? 283 ALA A CB    1 
ATOM   2183  N N     . ILE A 1 284 ? -50.578 -21.822 -22.361  1.00 49.57  ? 284 ILE A N     1 
ATOM   2184  C CA    . ILE A 1 284 ? -50.817 -22.459 -21.065  1.00 56.78  ? 284 ILE A CA    1 
ATOM   2185  C C     . ILE A 1 284 ? -51.608 -23.763 -21.251  1.00 53.69  ? 284 ILE A C     1 
ATOM   2186  O O     . ILE A 1 284 ? -51.450 -24.704 -20.481  1.00 49.39  ? 284 ILE A O     1 
ATOM   2187  C CB    . ILE A 1 284 ? -51.544 -21.504 -20.085  1.00 59.27  ? 284 ILE A CB    1 
ATOM   2188  C CG1   . ILE A 1 284 ? -50.744 -20.231 -19.781  1.00 58.57  ? 284 ILE A CG1   1 
ATOM   2189  C CG2   . ILE A 1 284 ? -51.929 -22.227 -18.801  1.00 60.65  ? 284 ILE A CG2   1 
ATOM   2190  C CD1   . ILE A 1 284 ? -49.332 -20.482 -19.277  1.00 61.29  ? 284 ILE A CD1   1 
ATOM   2191  N N     . THR A 1 285 ? -52.484 -23.814 -22.258  1.00 47.51  ? 285 THR A N     1 
ATOM   2192  C CA    . THR A 1 285 ? -53.391 -24.937 -22.389  1.00 46.69  ? 285 THR A CA    1 
ATOM   2193  C C     . THR A 1 285 ? -53.425 -25.495 -23.809  1.00 47.14  ? 285 THR A C     1 
ATOM   2194  O O     . THR A 1 285 ? -54.246 -26.363 -24.043  1.00 47.18  ? 285 THR A O     1 
ATOM   2195  C CB    . THR A 1 285 ? -54.828 -24.579 -21.993  1.00 42.20  ? 285 THR A CB    1 
ATOM   2196  O OG1   . THR A 1 285 ? -55.423 -23.717 -22.958  1.00 37.95  ? 285 THR A OG1   1 
ATOM   2197  C CG2   . THR A 1 285 ? -54.909 -23.936 -20.636  1.00 43.07  ? 285 THR A CG2   1 
ATOM   2198  N N     . ARG A 1 286 ? -52.610 -24.968 -24.743  1.00 43.36  ? 286 ARG A N     1 
ATOM   2199  C CA    . ARG A 1 286 ? -52.567 -25.467 -26.104  1.00 38.23  ? 286 ARG A CA    1 
ATOM   2200  C C     . ARG A 1 286 ? -51.140 -25.395 -26.624  1.00 43.34  ? 286 ARG A C     1 
ATOM   2201  O O     . ARG A 1 286 ? -50.266 -24.824 -25.957  1.00 41.74  ? 286 ARG A O     1 
ATOM   2202  C CB    . ARG A 1 286 ? -53.479 -24.649 -27.009  1.00 38.36  ? 286 ARG A CB    1 
ATOM   2203  C CG    . ARG A 1 286 ? -54.952 -24.658 -26.626  1.00 42.38  ? 286 ARG A CG    1 
ATOM   2204  C CD    . ARG A 1 286 ? -55.698 -25.875 -27.153  1.00 45.72  ? 286 ARG A CD    1 
ATOM   2205  N NE    . ARG A 1 286 ? -57.141 -25.833 -26.918  1.00 45.12  ? 286 ARG A NE    1 
ATOM   2206  C CZ    . ARG A 1 286 ? -57.718 -26.001 -25.725  1.00 49.77  ? 286 ARG A CZ    1 
ATOM   2207  N NH1   . ARG A 1 286 ? -56.982 -26.313 -24.669  1.00 49.35  ? 286 ARG A NH1   1 
ATOM   2208  N NH2   . ARG A 1 286 ? -59.029 -25.838 -25.582  1.00 49.40  ? 286 ARG A NH2   1 
ATOM   2209  N N     . THR A 1 287 ? -50.914 -25.997 -27.805  1.00 41.79  ? 287 THR A N     1 
ATOM   2210  C CA    . THR A 1 287 ? -49.615 -25.968 -28.466  1.00 46.81  ? 287 THR A CA    1 
ATOM   2211  C C     . THR A 1 287 ? -49.829 -25.504 -29.901  1.00 47.95  ? 287 THR A C     1 
ATOM   2212  O O     . THR A 1 287 ? -50.960 -25.584 -30.390  1.00 42.14  ? 287 THR A O     1 
ATOM   2213  C CB    . THR A 1 287 ? -48.884 -27.324 -28.466  1.00 48.71  ? 287 THR A CB    1 
ATOM   2214  O OG1   . THR A 1 287 ? -49.539 -28.207 -29.379  1.00 47.46  ? 287 THR A OG1   1 
ATOM   2215  C CG2   . THR A 1 287 ? -48.789 -27.989 -27.109  1.00 45.21  ? 287 THR A CG2   1 
ATOM   2216  N N     . LYS A 1 288 ? -48.739 -25.055 -30.556  1.00 46.14  ? 288 LYS A N     1 
ATOM   2217  C CA    . LYS A 1 288 ? -48.847 -24.404 -31.860  1.00 50.42  ? 288 LYS A CA    1 
ATOM   2218  C C     . LYS A 1 288 ? -49.395 -25.369 -32.900  1.00 43.25  ? 288 LYS A C     1 
ATOM   2219  O O     . LYS A 1 288 ? -50.152 -24.962 -33.779  1.00 52.82  ? 288 LYS A O     1 
ATOM   2220  C CB    . LYS A 1 288 ? -47.511 -23.870 -32.399  1.00 53.03  ? 288 LYS A CB    1 
ATOM   2221  C CG    . LYS A 1 288 ? -47.626 -23.340 -33.819  1.00 56.14  ? 288 LYS A CG    1 
ATOM   2222  C CD    . LYS A 1 288 ? -46.511 -22.451 -34.308  1.00 59.09  ? 288 LYS A CD    1 
ATOM   2223  C CE    . LYS A 1 288 ? -45.211 -23.172 -34.545  1.00 57.61  ? 288 LYS A CE    1 
ATOM   2224  N NZ    . LYS A 1 288 ? -44.554 -22.634 -35.759  1.00 56.11  ? 288 LYS A NZ    1 
ATOM   2225  N N     . SER A 1 289 ? -48.973 -26.627 -32.811  1.00 43.53  ? 289 SER A N     1 
ATOM   2226  C CA    . SER A 1 289 ? -49.258 -27.618 -33.844  1.00 50.42  ? 289 SER A CA    1 
ATOM   2227  C C     . SER A 1 289 ? -50.727 -28.062 -33.812  1.00 50.53  ? 289 SER A C     1 
ATOM   2228  O O     . SER A 1 289 ? -51.214 -28.673 -34.763  1.00 48.44  ? 289 SER A O     1 
ATOM   2229  C CB    . SER A 1 289 ? -48.352 -28.792 -33.672  1.00 50.02  ? 289 SER A CB    1 
ATOM   2230  O OG    . SER A 1 289 ? -48.622 -29.438 -32.427  1.00 49.09  ? 289 SER A OG    1 
ATOM   2231  N N     . GLN A 1 290 ? -51.434 -27.731 -32.725  1.00 44.35  ? 290 GLN A N     1 
ATOM   2232  C CA    . GLN A 1 290 ? -52.861 -27.978 -32.619  1.00 42.35  ? 290 GLN A CA    1 
ATOM   2233  C C     . GLN A 1 290 ? -53.643 -26.957 -33.430  1.00 43.40  ? 290 GLN A C     1 
ATOM   2234  O O     . GLN A 1 290 ? -54.860 -27.069 -33.541  1.00 47.84  ? 290 GLN A O     1 
ATOM   2235  C CB    . GLN A 1 290 ? -53.307 -27.907 -31.156  1.00 42.44  ? 290 GLN A CB    1 
ATOM   2236  C CG    . GLN A 1 290 ? -52.613 -28.928 -30.267  1.00 41.92  ? 290 GLN A CG    1 
ATOM   2237  C CD    . GLN A 1 290 ? -53.065 -28.886 -28.826  1.00 47.98  ? 290 GLN A CD    1 
ATOM   2238  O OE1   . GLN A 1 290 ? -52.850 -27.929 -28.085  1.00 55.84  ? 290 GLN A OE1   1 
ATOM   2239  N NE2   . GLN A 1 290 ? -53.683 -29.964 -28.390  1.00 53.36  ? 290 GLN A NE2   1 
ATOM   2240  N N     . TYR A 1 291 ? -52.949 -25.938 -33.956  1.00 45.47  ? 291 TYR A N     1 
ATOM   2241  C CA    . TYR A 1 291 ? -53.614 -24.873 -34.694  1.00 43.23  ? 291 TYR A CA    1 
ATOM   2242  C C     . TYR A 1 291 ? -52.961 -24.580 -36.050  1.00 42.03  ? 291 TYR A C     1 
ATOM   2243  O O     . TYR A 1 291 ? -53.637 -24.034 -36.915  1.00 39.18  ? 291 TYR A O     1 
ATOM   2244  C CB    . TYR A 1 291 ? -53.681 -23.596 -33.854  1.00 40.68  ? 291 TYR A CB    1 
ATOM   2245  C CG    . TYR A 1 291 ? -54.770 -23.603 -32.830  1.00 40.96  ? 291 TYR A CG    1 
ATOM   2246  C CD1   . TYR A 1 291 ? -56.087 -23.276 -33.163  1.00 40.62  ? 291 TYR A CD1   1 
ATOM   2247  C CD2   . TYR A 1 291 ? -54.489 -24.011 -31.533  1.00 44.64  ? 291 TYR A CD2   1 
ATOM   2248  C CE1   . TYR A 1 291 ? -57.107 -23.309 -32.211  1.00 39.72  ? 291 TYR A CE1   1 
ATOM   2249  C CE2   . TYR A 1 291 ? -55.502 -24.087 -30.585  1.00 49.69  ? 291 TYR A CE2   1 
ATOM   2250  C CZ    . TYR A 1 291 ? -56.807 -23.740 -30.924  1.00 42.77  ? 291 TYR A CZ    1 
ATOM   2251  O OH    . TYR A 1 291 ? -57.748 -23.809 -29.933  1.00 48.26  ? 291 TYR A OH    1 
ATOM   2252  N N     . TYR A 1 292 ? -51.669 -24.878 -36.235  1.00 44.48  ? 292 TYR A N     1 
ATOM   2253  C CA    . TYR A 1 292 ? -51.030 -24.519 -37.483  1.00 47.83  ? 292 TYR A CA    1 
ATOM   2254  C C     . TYR A 1 292 ? -49.919 -25.506 -37.829  1.00 53.22  ? 292 TYR A C     1 
ATOM   2255  O O     . TYR A 1 292 ? -49.111 -25.856 -36.979  1.00 54.83  ? 292 TYR A O     1 
ATOM   2256  C CB    . TYR A 1 292 ? -50.552 -23.071 -37.385  1.00 51.71  ? 292 TYR A CB    1 
ATOM   2257  C CG    . TYR A 1 292 ? -49.772 -22.541 -38.565  1.00 53.37  ? 292 TYR A CG    1 
ATOM   2258  C CD1   . TYR A 1 292 ? -50.382 -22.297 -39.789  1.00 56.95  ? 292 TYR A CD1   1 
ATOM   2259  C CD2   . TYR A 1 292 ? -48.424 -22.225 -38.444  1.00 52.82  ? 292 TYR A CD2   1 
ATOM   2260  C CE1   . TYR A 1 292 ? -49.669 -21.814 -40.880  1.00 53.40  ? 292 TYR A CE1   1 
ATOM   2261  C CE2   . TYR A 1 292 ? -47.700 -21.714 -39.510  1.00 54.75  ? 292 TYR A CE2   1 
ATOM   2262  C CZ    . TYR A 1 292 ? -48.322 -21.523 -40.736  1.00 60.75  ? 292 TYR A CZ    1 
ATOM   2263  O OH    . TYR A 1 292 ? -47.593 -21.016 -41.782  1.00 65.59  ? 292 TYR A OH    1 
ATOM   2264  N N     . ASP A 1 293 ? -49.877 -25.874 -39.116  1.00 62.94  ? 293 ASP A N     1 
ATOM   2265  C CA    . ASP A 1 293 ? -48.911 -26.801 -39.683  1.00 80.94  ? 293 ASP A CA    1 
ATOM   2266  C C     . ASP A 1 293 ? -47.525 -26.177 -39.872  1.00 74.51  ? 293 ASP A C     1 
ATOM   2267  O O     . ASP A 1 293 ? -46.530 -26.881 -39.752  1.00 81.26  ? 293 ASP A O     1 
ATOM   2268  C CB    . ASP A 1 293 ? -49.331 -27.256 -41.090  1.00 94.12  ? 293 ASP A CB    1 
ATOM   2269  C CG    . ASP A 1 293 ? -50.546 -28.167 -41.151  1.00 108.23 ? 293 ASP A CG    1 
ATOM   2270  O OD1   . ASP A 1 293 ? -50.491 -29.274 -40.570  1.00 102.81 ? 293 ASP A OD1   1 
ATOM   2271  O OD2   . ASP A 1 293 ? -51.530 -27.777 -41.810  1.00 117.38 ? 293 ASP A OD2   1 
ATOM   2272  N N     . GLY A 1 294 ? -47.451 -24.909 -40.296  1.00 65.18  ? 294 GLY A N     1 
ATOM   2273  C CA    . GLY A 1 294 ? -46.209 -24.360 -40.832  1.00 68.98  ? 294 GLY A CA    1 
ATOM   2274  C C     . GLY A 1 294 ? -45.120 -24.188 -39.769  1.00 65.79  ? 294 GLY A C     1 
ATOM   2275  O O     . GLY A 1 294 ? -45.440 -24.074 -38.585  1.00 57.63  ? 294 GLY A O     1 
ATOM   2276  N N     . ASP A 1 295 ? -43.842 -24.154 -40.201  1.00 69.00  ? 295 ASP A N     1 
ATOM   2277  C CA    . ASP A 1 295 ? -42.707 -23.937 -39.297  1.00 78.64  ? 295 ASP A CA    1 
ATOM   2278  C C     . ASP A 1 295 ? -42.630 -22.470 -38.849  1.00 77.05  ? 295 ASP A C     1 
ATOM   2279  O O     . ASP A 1 295 ? -41.958 -22.158 -37.858  1.00 67.23  ? 295 ASP A O     1 
ATOM   2280  C CB    . ASP A 1 295 ? -41.352 -24.323 -39.909  1.00 76.44  ? 295 ASP A CB    1 
ATOM   2281  C CG    . ASP A 1 295 ? -41.343 -25.645 -40.659  1.00 93.12  ? 295 ASP A CG    1 
ATOM   2282  O OD1   . ASP A 1 295 ? -41.580 -26.688 -40.009  1.00 100.40 ? 295 ASP A OD1   1 
ATOM   2283  O OD2   . ASP A 1 295 ? -41.107 -25.620 -41.899  1.00 91.46  ? 295 ASP A OD2   1 
ATOM   2284  N N     . GLY A 1 296 ? -43.313 -21.573 -39.581  1.00 72.34  ? 296 GLY A N     1 
ATOM   2285  C CA    . GLY A 1 296 ? -43.266 -20.154 -39.277  1.00 82.79  ? 296 GLY A CA    1 
ATOM   2286  C C     . GLY A 1 296 ? -44.091 -19.784 -38.044  1.00 78.67  ? 296 GLY A C     1 
ATOM   2287  O O     . GLY A 1 296 ? -44.672 -20.637 -37.373  1.00 78.46  ? 296 GLY A O     1 
ATOM   2288  N N     . PRO A 1 297 ? -44.173 -18.481 -37.709  1.00 60.54  ? 297 PRO A N     1 
ATOM   2289  C CA    . PRO A 1 297 ? -45.073 -18.016 -36.660  1.00 55.15  ? 297 PRO A CA    1 
ATOM   2290  C C     . PRO A 1 297 ? -46.480 -18.036 -37.246  1.00 51.15  ? 297 PRO A C     1 
ATOM   2291  O O     . PRO A 1 297 ? -46.626 -18.153 -38.463  1.00 41.56  ? 297 PRO A O     1 
ATOM   2292  C CB    . PRO A 1 297 ? -44.534 -16.607 -36.348  1.00 56.15  ? 297 PRO A CB    1 
ATOM   2293  C CG    . PRO A 1 297 ? -43.900 -16.125 -37.644  1.00 51.85  ? 297 PRO A CG    1 
ATOM   2294  C CD    . PRO A 1 297 ? -43.414 -17.388 -38.331  1.00 58.94  ? 297 PRO A CD    1 
ATOM   2295  N N     . ILE A 1 298 ? -47.482 -17.852 -36.380  1.00 50.10  ? 298 ILE A N     1 
ATOM   2296  C CA    . ILE A 1 298 ? -48.871 -18.087 -36.741  1.00 47.06  ? 298 ILE A CA    1 
ATOM   2297  C C     . ILE A 1 298 ? -49.367 -16.928 -37.585  1.00 50.08  ? 298 ILE A C     1 
ATOM   2298  O O     . ILE A 1 298 ? -49.111 -15.763 -37.281  1.00 55.96  ? 298 ILE A O     1 
ATOM   2299  C CB    . ILE A 1 298 ? -49.791 -18.343 -35.519  1.00 46.75  ? 298 ILE A CB    1 
ATOM   2300  C CG1   . ILE A 1 298 ? -49.868 -17.166 -34.539  1.00 49.95  ? 298 ILE A CG1   1 
ATOM   2301  C CG2   . ILE A 1 298 ? -49.386 -19.626 -34.793  1.00 46.92  ? 298 ILE A CG2   1 
ATOM   2302  C CD1   . ILE A 1 298 ? -51.094 -17.197 -33.640  1.00 48.92  ? 298 ILE A CD1   1 
ATOM   2303  N N     . PRO A 1 299 ? -50.084 -17.221 -38.691  1.00 57.96  ? 299 PRO A N     1 
ATOM   2304  C CA    . PRO A 1 299 ? -50.789 -16.183 -39.442  1.00 58.91  ? 299 PRO A CA    1 
ATOM   2305  C C     . PRO A 1 299 ? -51.988 -15.638 -38.679  1.00 49.96  ? 299 PRO A C     1 
ATOM   2306  O O     . PRO A 1 299 ? -52.463 -16.293 -37.754  1.00 45.87  ? 299 PRO A O     1 
ATOM   2307  C CB    . PRO A 1 299 ? -51.254 -16.878 -40.735  1.00 53.60  ? 299 PRO A CB    1 
ATOM   2308  C CG    . PRO A 1 299 ? -51.243 -18.352 -40.400  1.00 52.91  ? 299 PRO A CG    1 
ATOM   2309  C CD    . PRO A 1 299 ? -50.178 -18.537 -39.341  1.00 53.01  ? 299 PRO A CD    1 
ATOM   2310  N N     . PRO A 1 300 ? -52.495 -14.439 -39.062  1.00 54.18  ? 300 PRO A N     1 
ATOM   2311  C CA    . PRO A 1 300 ? -53.683 -13.836 -38.450  1.00 59.51  ? 300 PRO A CA    1 
ATOM   2312  C C     . PRO A 1 300 ? -54.936 -14.694 -38.378  1.00 51.55  ? 300 PRO A C     1 
ATOM   2313  O O     . PRO A 1 300 ? -55.713 -14.522 -37.443  1.00 53.63  ? 300 PRO A O     1 
ATOM   2314  C CB    . PRO A 1 300 ? -54.004 -12.638 -39.367  1.00 53.63  ? 300 PRO A CB    1 
ATOM   2315  C CG    . PRO A 1 300 ? -52.643 -12.225 -39.863  1.00 52.98  ? 300 PRO A CG    1 
ATOM   2316  C CD    . PRO A 1 300 ? -51.897 -13.531 -40.052  1.00 50.69  ? 300 PRO A CD    1 
ATOM   2317  N N     . SER A 1 301 ? -55.174 -15.520 -39.404  1.00 48.18  ? 301 SER A N     1 
ATOM   2318  C CA    . SER A 1 301 ? -56.406 -16.301 -39.455  1.00 48.58  ? 301 SER A CA    1 
ATOM   2319  C C     . SER A 1 301 ? -56.413 -17.334 -38.322  1.00 48.21  ? 301 SER A C     1 
ATOM   2320  O O     . SER A 1 301 ? -57.487 -17.664 -37.789  1.00 43.21  ? 301 SER A O     1 
ATOM   2321  C CB    . SER A 1 301 ? -56.585 -16.969 -40.787  1.00 42.33  ? 301 SER A CB    1 
ATOM   2322  O OG    . SER A 1 301 ? -55.409 -17.687 -41.100  1.00 43.90  ? 301 SER A OG    1 
ATOM   2323  N N     . VAL A 1 302 ? -55.211 -17.832 -37.963  1.00 39.44  ? 302 VAL A N     1 
ATOM   2324  C CA    . VAL A 1 302 ? -55.087 -18.805 -36.896  1.00 43.80  ? 302 VAL A CA    1 
ATOM   2325  C C     . VAL A 1 302 ? -55.300 -18.095 -35.565  1.00 50.33  ? 302 VAL A C     1 
ATOM   2326  O O     . VAL A 1 302 ? -56.009 -18.600 -34.702  1.00 60.76  ? 302 VAL A O     1 
ATOM   2327  C CB    . VAL A 1 302 ? -53.736 -19.539 -36.913  1.00 49.09  ? 302 VAL A CB    1 
ATOM   2328  C CG1   . VAL A 1 302 ? -53.448 -20.248 -35.586  1.00 44.74  ? 302 VAL A CG1   1 
ATOM   2329  C CG2   . VAL A 1 302 ? -53.639 -20.507 -38.084  1.00 49.74  ? 302 VAL A CG2   1 
ATOM   2330  N N     . ALA A 1 303 ? -54.676 -16.924 -35.398  1.00 55.70  ? 303 ALA A N     1 
ATOM   2331  C CA    . ALA A 1 303 ? -54.919 -16.107 -34.219  1.00 46.41  ? 303 ALA A CA    1 
ATOM   2332  C C     . ALA A 1 303 ? -56.422 -16.005 -33.945  1.00 44.79  ? 303 ALA A C     1 
ATOM   2333  O O     . ALA A 1 303 ? -56.833 -16.210 -32.804  1.00 43.54  ? 303 ALA A O     1 
ATOM   2334  C CB    . ALA A 1 303 ? -54.269 -14.762 -34.384  1.00 48.04  ? 303 ALA A CB    1 
ATOM   2335  N N     . LYS A 1 304 ? -57.244 -15.736 -34.976  1.00 47.12  ? 304 LYS A N     1 
ATOM   2336  C CA    . LYS A 1 304 ? -58.682 -15.581 -34.774  1.00 55.18  ? 304 LYS A CA    1 
ATOM   2337  C C     . LYS A 1 304 ? -59.281 -16.886 -34.260  1.00 51.75  ? 304 LYS A C     1 
ATOM   2338  O O     . LYS A 1 304 ? -60.095 -16.868 -33.345  1.00 46.83  ? 304 LYS A O     1 
ATOM   2339  C CB    . LYS A 1 304 ? -59.409 -15.097 -36.033  1.00 60.66  ? 304 LYS A CB    1 
ATOM   2340  C CG    . LYS A 1 304 ? -59.540 -13.580 -36.103  1.00 87.95  ? 304 LYS A CG    1 
ATOM   2341  C CD    . LYS A 1 304 ? -59.569 -12.981 -37.495  1.00 94.83  ? 304 LYS A CD    1 
ATOM   2342  C CE    . LYS A 1 304 ? -59.608 -11.467 -37.460  1.00 91.84  ? 304 LYS A CE    1 
ATOM   2343  N NZ    . LYS A 1 304 ? -59.347 -10.900 -38.802  1.00 88.62  ? 304 LYS A NZ    1 
ATOM   2344  N N     . THR A 1 305 ? -58.859 -18.007 -34.841  1.00 47.77  ? 305 THR A N     1 
ATOM   2345  C CA    . THR A 1 305 ? -59.357 -19.311 -34.436  1.00 56.61  ? 305 THR A CA    1 
ATOM   2346  C C     . THR A 1 305 ? -59.135 -19.487 -32.918  1.00 51.32  ? 305 THR A C     1 
ATOM   2347  O O     . THR A 1 305 ? -60.055 -19.827 -32.157  1.00 41.99  ? 305 THR A O     1 
ATOM   2348  C CB    . THR A 1 305 ? -58.735 -20.383 -35.358  1.00 60.14  ? 305 THR A CB    1 
ATOM   2349  O OG1   . THR A 1 305 ? -59.217 -20.181 -36.691  1.00 63.79  ? 305 THR A OG1   1 
ATOM   2350  C CG2   . THR A 1 305 ? -59.012 -21.807 -34.923  1.00 55.76  ? 305 THR A CG2   1 
ATOM   2351  N N     . MET A 1 306 ? -57.898 -19.227 -32.483  1.00 44.69  ? 306 MET A N     1 
ATOM   2352  C CA    . MET A 1 306 ? -57.506 -19.418 -31.099  1.00 50.00  ? 306 MET A CA    1 
ATOM   2353  C C     . MET A 1 306 ? -58.329 -18.508 -30.188  1.00 43.91  ? 306 MET A C     1 
ATOM   2354  O O     . MET A 1 306 ? -58.760 -18.931 -29.136  1.00 44.67  ? 306 MET A O     1 
ATOM   2355  C CB    . MET A 1 306 ? -56.017 -19.117 -30.913  1.00 49.15  ? 306 MET A CB    1 
ATOM   2356  C CG    . MET A 1 306 ? -55.132 -20.219 -31.400  1.00 51.69  ? 306 MET A CG    1 
ATOM   2357  S SD    . MET A 1 306 ? -53.464 -19.642 -31.749  1.00 57.18  ? 306 MET A SD    1 
ATOM   2358  C CE    . MET A 1 306 ? -52.849 -19.514 -30.075  1.00 63.20  ? 306 MET A CE    1 
ATOM   2359  N N     . MET A 1 307 ? -58.545 -17.264 -30.594  1.00 38.33  ? 307 MET A N     1 
ATOM   2360  C CA    . MET A 1 307 ? -59.360 -16.359 -29.814  1.00 41.55  ? 307 MET A CA    1 
ATOM   2361  C C     . MET A 1 307 ? -60.769 -16.920 -29.614  1.00 38.70  ? 307 MET A C     1 
ATOM   2362  O O     . MET A 1 307 ? -61.254 -16.936 -28.495  1.00 40.13  ? 307 MET A O     1 
ATOM   2363  C CB    . MET A 1 307 ? -59.442 -14.987 -30.492  1.00 42.64  ? 307 MET A CB    1 
ATOM   2364  C CG    . MET A 1 307 ? -58.129 -14.241 -30.458  1.00 43.88  ? 307 MET A CG    1 
ATOM   2365  S SD    . MET A 1 307 ? -58.117 -12.744 -31.499  1.00 47.29  ? 307 MET A SD    1 
ATOM   2366  C CE    . MET A 1 307 ? -59.688 -11.997 -31.061  1.00 42.92  ? 307 MET A CE    1 
ATOM   2367  N N     . ALA A 1 308 ? -61.429 -17.363 -30.686  1.00 47.18  ? 308 ALA A N     1 
ATOM   2368  C CA    . ALA A 1 308 ? -62.794 -17.889 -30.620  1.00 49.03  ? 308 ALA A CA    1 
ATOM   2369  C C     . ALA A 1 308 ? -62.874 -19.188 -29.820  1.00 49.15  ? 308 ALA A C     1 
ATOM   2370  O O     . ALA A 1 308 ? -63.833 -19.357 -29.071  1.00 46.99  ? 308 ALA A O     1 
ATOM   2371  C CB    . ALA A 1 308 ? -63.347 -18.107 -31.999  1.00 48.58  ? 308 ALA A CB    1 
ATOM   2372  N N     . ASP A 1 309 ? -61.880 -20.086 -29.948  1.00 43.39  ? 309 ASP A N     1 
ATOM   2373  C CA    . ASP A 1 309 ? -61.910 -21.329 -29.186  1.00 48.06  ? 309 ASP A CA    1 
ATOM   2374  C C     . ASP A 1 309 ? -61.753 -21.095 -27.682  1.00 57.03  ? 309 ASP A C     1 
ATOM   2375  O O     . ASP A 1 309 ? -62.438 -21.706 -26.868  1.00 55.49  ? 309 ASP A O     1 
ATOM   2376  C CB    . ASP A 1 309 ? -60.789 -22.293 -29.568  1.00 46.77  ? 309 ASP A CB    1 
ATOM   2377  C CG    . ASP A 1 309 ? -61.021 -23.048 -30.860  1.00 54.48  ? 309 ASP A CG    1 
ATOM   2378  O OD1   . ASP A 1 309 ? -62.012 -22.694 -31.582  1.00 57.32  ? 309 ASP A OD1   1 
ATOM   2379  O OD2   . ASP A 1 309 ? -60.211 -23.983 -31.130  1.00 52.85  ? 309 ASP A OD2   1 
ATOM   2380  N N     . LEU A 1 310 ? -60.796 -20.239 -27.316  1.00 58.24  ? 310 LEU A N     1 
ATOM   2381  C CA    . LEU A 1 310 ? -60.265 -20.205 -25.968  1.00 47.60  ? 310 LEU A CA    1 
ATOM   2382  C C     . LEU A 1 310 ? -60.939 -19.117 -25.134  1.00 45.19  ? 310 LEU A C     1 
ATOM   2383  O O     . LEU A 1 310 ? -60.695 -19.099 -23.928  1.00 46.52  ? 310 LEU A O     1 
ATOM   2384  C CB    . LEU A 1 310 ? -58.762 -19.954 -26.051  1.00 44.51  ? 310 LEU A CB    1 
ATOM   2385  C CG    . LEU A 1 310 ? -57.945 -21.061 -26.690  1.00 47.57  ? 310 LEU A CG    1 
ATOM   2386  C CD1   . LEU A 1 310 ? -56.575 -20.556 -27.101  1.00 46.84  ? 310 LEU A CD1   1 
ATOM   2387  C CD2   . LEU A 1 310 ? -57.814 -22.223 -25.716  1.00 58.28  ? 310 LEU A CD2   1 
ATOM   2388  N N     . ASP A 1 311 ? -61.788 -18.279 -25.769  1.00 43.63  ? 311 ASP A N     1 
ATOM   2389  C CA    . ASP A 1 311 ? -62.313 -17.028 -25.204  1.00 48.99  ? 311 ASP A CA    1 
ATOM   2390  C C     . ASP A 1 311 ? -61.180 -16.161 -24.611  1.00 49.08  ? 311 ASP A C     1 
ATOM   2391  O O     . ASP A 1 311 ? -61.130 -15.895 -23.407  1.00 50.60  ? 311 ASP A O     1 
ATOM   2392  C CB    . ASP A 1 311 ? -63.435 -17.283 -24.197  1.00 49.80  ? 311 ASP A CB    1 
ATOM   2393  C CG    . ASP A 1 311 ? -64.722 -17.885 -24.744  1.00 52.42  ? 311 ASP A CG    1 
ATOM   2394  O OD1   . ASP A 1 311 ? -64.773 -18.185 -25.943  1.00 50.45  ? 311 ASP A OD1   1 
ATOM   2395  O OD2   . ASP A 1 311 ? -65.692 -18.017 -23.948  1.00 51.66  ? 311 ASP A OD2   1 
ATOM   2396  N N     . LEU A 1 312 ? -60.252 -15.765 -25.492  1.00 41.23  ? 312 LEU A N     1 
ATOM   2397  C CA    . LEU A 1 312 ? -59.117 -14.909 -25.209  1.00 46.31  ? 312 LEU A CA    1 
ATOM   2398  C C     . LEU A 1 312 ? -59.110 -13.838 -26.294  1.00 47.88  ? 312 LEU A C     1 
ATOM   2399  O O     . LEU A 1 312 ? -59.573 -14.095 -27.415  1.00 40.56  ? 312 LEU A O     1 
ATOM   2400  C CB    . LEU A 1 312 ? -57.801 -15.703 -25.269  1.00 46.29  ? 312 LEU A CB    1 
ATOM   2401  C CG    . LEU A 1 312 ? -57.603 -16.837 -24.261  1.00 52.20  ? 312 LEU A CG    1 
ATOM   2402  C CD1   . LEU A 1 312 ? -56.303 -17.587 -24.527  1.00 48.69  ? 312 LEU A CD1   1 
ATOM   2403  C CD2   . LEU A 1 312 ? -57.599 -16.319 -22.825  1.00 59.82  ? 312 LEU A CD2   1 
ATOM   2404  N N     . GLY A 1 313 ? -58.596 -12.651 -25.949  1.00 43.90  ? 313 GLY A N     1 
ATOM   2405  C CA    . GLY A 1 313 ? -58.412 -11.588 -26.925  1.00 47.92  ? 313 GLY A CA    1 
ATOM   2406  C C     . GLY A 1 313 ? -56.984 -11.598 -27.467  1.00 53.19  ? 313 GLY A C     1 
ATOM   2407  O O     . GLY A 1 313 ? -56.205 -12.529 -27.198  1.00 48.42  ? 313 GLY A O     1 
ATOM   2408  N N     . MET A 1 314 ? -56.629 -10.534 -28.196  1.00 48.70  ? 314 MET A N     1 
ATOM   2409  C CA    . MET A 1 314 ? -55.245 -10.342 -28.619  1.00 46.62  ? 314 MET A CA    1 
ATOM   2410  C C     . MET A 1 314 ? -54.438 -9.851  -27.421  1.00 40.80  ? 314 MET A C     1 
ATOM   2411  O O     . MET A 1 314 ? -53.268 -10.199 -27.259  1.00 40.25  ? 314 MET A O     1 
ATOM   2412  C CB    . MET A 1 314 ? -55.159 -9.328  -29.761  1.00 51.58  ? 314 MET A CB    1 
ATOM   2413  C CG    . MET A 1 314 ? -55.738 -9.853  -31.066  1.00 51.53  ? 314 MET A CG    1 
ATOM   2414  S SD    . MET A 1 314 ? -54.725 -11.171 -31.736  1.00 57.67  ? 314 MET A SD    1 
ATOM   2415  C CE    . MET A 1 314 ? -53.287 -10.246 -32.294  1.00 61.27  ? 314 MET A CE    1 
ATOM   2416  N N     . TRP A 1 315 ? -55.122 -9.109  -26.540  1.00 41.65  ? 315 TRP A N     1 
ATOM   2417  C CA    . TRP A 1 315 ? -54.597 -8.787  -25.218  1.00 41.28  ? 315 TRP A CA    1 
ATOM   2418  C C     . TRP A 1 315 ? -55.553 -9.251  -24.123  1.00 39.63  ? 315 TRP A C     1 
ATOM   2419  O O     . TRP A 1 315 ? -56.769 -9.152  -24.264  1.00 45.84  ? 315 TRP A O     1 
ATOM   2420  C CB    . TRP A 1 315 ? -54.363 -7.279  -25.125  1.00 42.21  ? 315 TRP A CB    1 
ATOM   2421  C CG    . TRP A 1 315 ? -53.363 -6.815  -26.126  1.00 35.99  ? 315 TRP A CG    1 
ATOM   2422  C CD1   . TRP A 1 315 ? -53.627 -6.183  -27.301  1.00 35.14  ? 315 TRP A CD1   1 
ATOM   2423  C CD2   . TRP A 1 315 ? -51.946 -7.042  -26.087  1.00 28.68  ? 315 TRP A CD2   1 
ATOM   2424  N NE1   . TRP A 1 315 ? -52.447 -5.961  -27.969  1.00 37.67  ? 315 TRP A NE1   1 
ATOM   2425  C CE2   . TRP A 1 315 ? -51.405 -6.483  -27.253  1.00 32.58  ? 315 TRP A CE2   1 
ATOM   2426  C CE3   . TRP A 1 315 ? -51.083 -7.664  -25.195  1.00 31.29  ? 315 TRP A CE3   1 
ATOM   2427  C CZ2   . TRP A 1 315 ? -50.038 -6.472  -27.515  1.00 37.08  ? 315 TRP A CZ2   1 
ATOM   2428  C CZ3   . TRP A 1 315 ? -49.730 -7.666  -25.451  1.00 33.62  ? 315 TRP A CZ3   1 
ATOM   2429  C CH2   . TRP A 1 315 ? -49.206 -7.066  -26.594  1.00 32.60  ? 315 TRP A CH2   1 
ATOM   2430  N N     . ASN A 1 316 ? -54.962 -9.691  -23.017  1.00 37.29  ? 316 ASN A N     1 
ATOM   2431  C CA    . ASN A 1 316 ? -55.667 -10.347 -21.938  1.00 39.53  ? 316 ASN A CA    1 
ATOM   2432  C C     . ASN A 1 316 ? -55.190 -9.765  -20.609  1.00 36.56  ? 316 ASN A C     1 
ATOM   2433  O O     . ASN A 1 316 ? -54.060 -9.990  -20.211  1.00 36.68  ? 316 ASN A O     1 
ATOM   2434  C CB    . ASN A 1 316 ? -55.434 -11.855 -22.051  1.00 41.65  ? 316 ASN A CB    1 
ATOM   2435  C CG    . ASN A 1 316 ? -55.964 -12.385 -23.365  1.00 46.21  ? 316 ASN A CG    1 
ATOM   2436  O OD1   . ASN A 1 316 ? -57.169 -12.590 -23.532  1.00 48.65  ? 316 ASN A OD1   1 
ATOM   2437  N ND2   . ASN A 1 316 ? -55.072 -12.568 -24.323  1.00 48.18  ? 316 ASN A ND2   1 
ATOM   2438  N N     . PHE A 1 317 ? -56.055 -9.014  -19.927  1.00 36.15  ? 317 PHE A N     1 
ATOM   2439  C CA    . PHE A 1 317 ? -55.701 -8.369  -18.671  1.00 38.40  ? 317 PHE A CA    1 
ATOM   2440  C C     . PHE A 1 317 ? -56.237 -9.220  -17.518  1.00 37.61  ? 317 PHE A C     1 
ATOM   2441  O O     . PHE A 1 317 ? -57.453 -9.338  -17.365  1.00 41.83  ? 317 PHE A O     1 
ATOM   2442  C CB    . PHE A 1 317 ? -56.212 -6.927  -18.663  1.00 37.84  ? 317 PHE A CB    1 
ATOM   2443  C CG    . PHE A 1 317 ? -56.177 -6.252  -17.313  1.00 43.73  ? 317 PHE A CG    1 
ATOM   2444  C CD1   . PHE A 1 317 ? -55.190 -6.543  -16.391  1.00 47.41  ? 317 PHE A CD1   1 
ATOM   2445  C CD2   . PHE A 1 317 ? -57.136 -5.312  -16.966  1.00 40.52  ? 317 PHE A CD2   1 
ATOM   2446  C CE1   . PHE A 1 317 ? -55.182 -5.922  -15.154  1.00 42.75  ? 317 PHE A CE1   1 
ATOM   2447  C CE2   . PHE A 1 317 ? -57.118 -4.691  -15.734  1.00 35.39  ? 317 PHE A CE2   1 
ATOM   2448  C CZ    . PHE A 1 317 ? -56.154 -5.012  -14.830  1.00 35.63  ? 317 PHE A CZ    1 
ATOM   2449  N N     . CYS A 1 318 ? -55.327 -9.891  -16.803  1.00 36.45  ? 318 CYS A N     1 
ATOM   2450  C CA    . CYS A 1 318 ? -55.685 -10.744 -15.678  1.00 48.05  ? 318 CYS A CA    1 
ATOM   2451  C C     . CYS A 1 318 ? -55.302 -10.009 -14.394  1.00 45.97  ? 318 CYS A C     1 
ATOM   2452  O O     . CYS A 1 318 ? -54.173 -9.564  -14.209  1.00 47.34  ? 318 CYS A O     1 
ATOM   2453  C CB    . CYS A 1 318 ? -55.156 -12.189 -15.772  1.00 47.58  ? 318 CYS A CB    1 
ATOM   2454  S SG    . CYS A 1 318 ? -53.368 -12.404 -16.046  1.00 53.68  ? 318 CYS A SG    1 
ATOM   2455  N N     . GLY A 1 319 ? -56.316 -9.773  -13.565  1.00 47.27  ? 319 GLY A N     1 
ATOM   2456  C CA    . GLY A 1 319 ? -56.139 -9.013  -12.340  1.00 51.33  ? 319 GLY A CA    1 
ATOM   2457  C C     . GLY A 1 319 ? -56.886 -9.655  -11.183  1.00 48.61  ? 319 GLY A C     1 
ATOM   2458  O O     . GLY A 1 319 ? -57.474 -10.714 -11.363  1.00 43.83  ? 319 GLY A O     1 
ATOM   2459  N N     . ALA A 1 320 ? -56.827 -9.013  -10.007  1.00 45.37  ? 320 ALA A N     1 
ATOM   2460  C CA    . ALA A 1 320 ? -57.532 -9.523  -8.856   1.00 43.02  ? 320 ALA A CA    1 
ATOM   2461  C C     . ALA A 1 320 ? -57.831 -8.420  -7.842   1.00 39.82  ? 320 ALA A C     1 
ATOM   2462  O O     . ALA A 1 320 ? -56.969 -7.628  -7.521   1.00 36.67  ? 320 ALA A O     1 
ATOM   2463  C CB    . ALA A 1 320 ? -56.734 -10.652 -8.254   1.00 43.38  ? 320 ALA A CB    1 
ATOM   2464  N N     . LEU A 1 321 ? -59.065 -8.443  -7.332   1.00 35.83  ? 321 LEU A N     1 
ATOM   2465  C CA    . LEU A 1 321 ? -59.525 -7.650  -6.220   1.00 38.99  ? 321 LEU A CA    1 
ATOM   2466  C C     . LEU A 1 321 ? -59.263 -8.386  -4.907   1.00 43.52  ? 321 LEU A C     1 
ATOM   2467  O O     . LEU A 1 321 ? -59.382 -9.617  -4.835   1.00 40.21  ? 321 LEU A O     1 
ATOM   2468  C CB    . LEU A 1 321 ? -61.022 -7.432  -6.413   1.00 40.24  ? 321 LEU A CB    1 
ATOM   2469  C CG    . LEU A 1 321 ? -61.418 -6.846  -7.772   1.00 40.11  ? 321 LEU A CG    1 
ATOM   2470  C CD1   . LEU A 1 321 ? -62.933 -6.856  -7.955   1.00 39.31  ? 321 LEU A CD1   1 
ATOM   2471  C CD2   . LEU A 1 321 ? -60.904 -5.422  -7.916   1.00 38.61  ? 321 LEU A CD2   1 
ATOM   2472  N N     . TYR A 1 322 ? -58.906 -7.595  -3.878   1.00 40.70  ? 322 TYR A N     1 
ATOM   2473  C CA    . TYR A 1 322 ? -58.610 -8.096  -2.542   1.00 40.73  ? 322 TYR A CA    1 
ATOM   2474  C C     . TYR A 1 322 ? -59.337 -7.240  -1.520   1.00 37.48  ? 322 TYR A C     1 
ATOM   2475  O O     . TYR A 1 322 ? -59.436 -6.042  -1.699   1.00 36.74  ? 322 TYR A O     1 
ATOM   2476  C CB    . TYR A 1 322 ? -57.105 -8.038  -2.223   1.00 40.71  ? 322 TYR A CB    1 
ATOM   2477  C CG    . TYR A 1 322 ? -56.224 -8.765  -3.213   1.00 39.15  ? 322 TYR A CG    1 
ATOM   2478  C CD1   . TYR A 1 322 ? -55.880 -8.156  -4.412   1.00 36.23  ? 322 TYR A CD1   1 
ATOM   2479  C CD2   . TYR A 1 322 ? -55.782 -10.067 -2.989   1.00 33.69  ? 322 TYR A CD2   1 
ATOM   2480  C CE1   . TYR A 1 322 ? -55.065 -8.788  -5.333   1.00 37.88  ? 322 TYR A CE1   1 
ATOM   2481  C CE2   . TYR A 1 322 ? -54.953 -10.708 -3.900   1.00 32.44  ? 322 TYR A CE2   1 
ATOM   2482  C CZ    . TYR A 1 322 ? -54.616 -10.077 -5.090   1.00 37.16  ? 322 TYR A CZ    1 
ATOM   2483  O OH    . TYR A 1 322 ? -53.837 -10.692 -6.060   1.00 35.68  ? 322 TYR A OH    1 
ATOM   2484  N N     . GLY A 1 323 ? -59.839 -7.866  -0.448   1.00 47.48  ? 323 GLY A N     1 
ATOM   2485  C CA    . GLY A 1 323 ? -60.450 -7.129  0.654    1.00 54.05  ? 323 GLY A CA    1 
ATOM   2486  C C     . GLY A 1 323 ? -61.933 -7.454  0.825    1.00 52.34  ? 323 GLY A C     1 
ATOM   2487  O O     . GLY A 1 323 ? -62.445 -8.358  0.164    1.00 49.43  ? 323 GLY A O     1 
ATOM   2488  N N     . PRO A 1 324 ? -62.652 -6.765  1.746    1.00 54.59  ? 324 PRO A N     1 
ATOM   2489  C CA    . PRO A 1 324 ? -64.060 -7.076  2.009    1.00 56.21  ? 324 PRO A CA    1 
ATOM   2490  C C     . PRO A 1 324 ? -64.936 -6.787  0.788    1.00 57.77  ? 324 PRO A C     1 
ATOM   2491  O O     . PRO A 1 324 ? -64.612 -5.912  -0.011   1.00 48.24  ? 324 PRO A O     1 
ATOM   2492  C CB    . PRO A 1 324 ? -64.471 -6.185  3.174    1.00 53.59  ? 324 PRO A CB    1 
ATOM   2493  C CG    . PRO A 1 324 ? -63.325 -5.209  3.391    1.00 55.19  ? 324 PRO A CG    1 
ATOM   2494  C CD    . PRO A 1 324 ? -62.148 -5.650  2.550    1.00 51.75  ? 324 PRO A CD    1 
ATOM   2495  N N     . PRO A 1 325 ? -66.069 -7.503  0.608    1.00 57.80  ? 325 PRO A N     1 
ATOM   2496  C CA    . PRO A 1 325 ? -66.887 -7.357  -0.594   1.00 54.57  ? 325 PRO A CA    1 
ATOM   2497  C C     . PRO A 1 325 ? -67.238 -5.915  -0.965   1.00 53.22  ? 325 PRO A C     1 
ATOM   2498  O O     . PRO A 1 325 ? -67.238 -5.583  -2.145   1.00 54.55  ? 325 PRO A O     1 
ATOM   2499  C CB    . PRO A 1 325 ? -68.132 -8.184  -0.241   1.00 56.80  ? 325 PRO A CB    1 
ATOM   2500  C CG    . PRO A 1 325 ? -67.586 -9.270  0.658    1.00 55.90  ? 325 PRO A CG    1 
ATOM   2501  C CD    . PRO A 1 325 ? -66.610 -8.512  1.536    1.00 60.46  ? 325 PRO A CD    1 
ATOM   2502  N N     . PRO A 1 326 ? -67.608 -5.020  -0.020   1.00 52.99  ? 326 PRO A N     1 
ATOM   2503  C CA    . PRO A 1 326 ? -67.869 -3.621  -0.367   1.00 53.97  ? 326 PRO A CA    1 
ATOM   2504  C C     . PRO A 1 326 ? -66.701 -2.890  -1.042   1.00 60.74  ? 326 PRO A C     1 
ATOM   2505  O O     . PRO A 1 326 ? -66.905 -2.107  -1.979   1.00 57.78  ? 326 PRO A O     1 
ATOM   2506  C CB    . PRO A 1 326 ? -68.250 -2.980  0.975    1.00 51.56  ? 326 PRO A CB    1 
ATOM   2507  C CG    . PRO A 1 326 ? -68.813 -4.125  1.780    1.00 54.81  ? 326 PRO A CG    1 
ATOM   2508  C CD    . PRO A 1 326 ? -67.965 -5.317  1.379    1.00 61.53  ? 326 PRO A CD    1 
ATOM   2509  N N     . VAL A 1 327 ? -65.465 -3.152  -0.598   1.00 58.25  ? 327 VAL A N     1 
ATOM   2510  C CA    . VAL A 1 327 ? -64.312 -2.502  -1.217   1.00 51.39  ? 327 VAL A CA    1 
ATOM   2511  C C     . VAL A 1 327 ? -64.109 -3.049  -2.630   1.00 51.11  ? 327 VAL A C     1 
ATOM   2512  O O     . VAL A 1 327 ? -63.923 -2.290  -3.586   1.00 56.18  ? 327 VAL A O     1 
ATOM   2513  C CB    . VAL A 1 327 ? -63.056 -2.650  -0.343   1.00 51.97  ? 327 VAL A CB    1 
ATOM   2514  C CG1   . VAL A 1 327 ? -61.825 -2.023  -0.992   1.00 53.82  ? 327 VAL A CG1   1 
ATOM   2515  C CG2   . VAL A 1 327 ? -63.285 -2.046  1.037    1.00 55.52  ? 327 VAL A CG2   1 
ATOM   2516  N N     . MET A 1 328 ? -64.218 -4.373  -2.760   1.00 46.80  ? 328 MET A N     1 
ATOM   2517  C CA    . MET A 1 328 ? -64.081 -5.053  -4.037   1.00 47.63  ? 328 MET A CA    1 
ATOM   2518  C C     . MET A 1 328 ? -65.117 -4.526  -5.031   1.00 46.41  ? 328 MET A C     1 
ATOM   2519  O O     . MET A 1 328 ? -64.750 -4.167  -6.145   1.00 46.36  ? 328 MET A O     1 
ATOM   2520  C CB    . MET A 1 328 ? -64.180 -6.572  -3.843   1.00 45.02  ? 328 MET A CB    1 
ATOM   2521  C CG    . MET A 1 328 ? -62.933 -7.137  -3.136   1.00 49.06  ? 328 MET A CG    1 
ATOM   2522  S SD    . MET A 1 328 ? -62.681 -8.947  -3.234   1.00 52.58  ? 328 MET A SD    1 
ATOM   2523  C CE    . MET A 1 328 ? -64.295 -9.504  -2.676   1.00 46.46  ? 328 MET A CE    1 
ATOM   2524  N N     . ASP A 1 329 ? -66.380 -4.412  -4.603   1.00 46.14  ? 329 ASP A N     1 
ATOM   2525  C CA    . ASP A 1 329 ? -67.433 -3.908  -5.468   1.00 50.17  ? 329 ASP A CA    1 
ATOM   2526  C C     . ASP A 1 329 ? -67.052 -2.528  -5.959   1.00 48.98  ? 329 ASP A C     1 
ATOM   2527  O O     . ASP A 1 329 ? -67.104 -2.273  -7.146   1.00 58.52  ? 329 ASP A O     1 
ATOM   2528  C CB    . ASP A 1 329 ? -68.793 -3.836  -4.773   1.00 53.18  ? 329 ASP A CB    1 
ATOM   2529  C CG    . ASP A 1 329 ? -69.420 -5.197  -4.528   1.00 66.19  ? 329 ASP A CG    1 
ATOM   2530  O OD1   . ASP A 1 329 ? -68.949 -6.204  -5.122   1.00 70.17  ? 329 ASP A OD1   1 
ATOM   2531  O OD2   . ASP A 1 329 ? -70.344 -5.252  -3.710   1.00 81.63  ? 329 ASP A OD2   1 
ATOM   2532  N N     . THR A 1 330 ? -66.632 -1.666  -5.038   1.00 49.74  ? 330 THR A N     1 
ATOM   2533  C CA    . THR A 1 330 ? -66.246 -0.318  -5.402   1.00 51.49  ? 330 THR A CA    1 
ATOM   2534  C C     . THR A 1 330 ? -65.064 -0.294  -6.377   1.00 52.31  ? 330 THR A C     1 
ATOM   2535  O O     . THR A 1 330 ? -65.088 0.491   -7.326   1.00 55.38  ? 330 THR A O     1 
ATOM   2536  C CB    . THR A 1 330 ? -65.905 0.517   -4.163   1.00 49.73  ? 330 THR A CB    1 
ATOM   2537  O OG1   . THR A 1 330 ? -67.039 0.492   -3.306   1.00 50.00  ? 330 THR A OG1   1 
ATOM   2538  C CG2   . THR A 1 330 ? -65.556 1.953   -4.500   1.00 47.67  ? 330 THR A CG2   1 
ATOM   2539  N N     . LEU A 1 331 ? -64.009 -1.088  -6.126   1.00 44.38  ? 331 LEU A N     1 
ATOM   2540  C CA    . LEU A 1 331 ? -62.824 -1.026  -6.976   1.00 45.50  ? 331 LEU A CA    1 
ATOM   2541  C C     . LEU A 1 331 ? -63.163 -1.557  -8.375   1.00 46.48  ? 331 LEU A C     1 
ATOM   2542  O O     . LEU A 1 331 ? -62.689 -1.060  -9.399   1.00 43.01  ? 331 LEU A O     1 
ATOM   2543  C CB    . LEU A 1 331 ? -61.695 -1.866  -6.357   1.00 48.10  ? 331 LEU A CB    1 
ATOM   2544  C CG    . LEU A 1 331 ? -61.053 -1.398  -5.048   1.00 44.89  ? 331 LEU A CG    1 
ATOM   2545  C CD1   . LEU A 1 331 ? -59.871 -2.294  -4.726   1.00 50.08  ? 331 LEU A CD1   1 
ATOM   2546  C CD2   . LEU A 1 331 ? -60.621 0.071   -5.078   1.00 44.60  ? 331 LEU A CD2   1 
ATOM   2547  N N     . TRP A 1 332 ? -64.006 -2.592  -8.406   1.00 48.06  ? 332 TRP A N     1 
ATOM   2548  C CA    . TRP A 1 332 ? -64.459 -3.172  -9.653   1.00 45.10  ? 332 TRP A CA    1 
ATOM   2549  C C     . TRP A 1 332 ? -65.202 -2.138  -10.508  1.00 49.31  ? 332 TRP A C     1 
ATOM   2550  O O     . TRP A 1 332 ? -64.947 -2.047  -11.717  1.00 47.04  ? 332 TRP A O     1 
ATOM   2551  C CB    . TRP A 1 332 ? -65.290 -4.420  -9.378   1.00 43.69  ? 332 TRP A CB    1 
ATOM   2552  C CG    . TRP A 1 332 ? -65.755 -5.044  -10.650  1.00 46.45  ? 332 TRP A CG    1 
ATOM   2553  C CD1   . TRP A 1 332 ? -67.045 -5.208  -11.052  1.00 42.56  ? 332 TRP A CD1   1 
ATOM   2554  C CD2   . TRP A 1 332 ? -64.922 -5.552  -11.713  1.00 45.78  ? 332 TRP A CD2   1 
ATOM   2555  N NE1   . TRP A 1 332 ? -67.071 -5.775  -12.300  1.00 49.32  ? 332 TRP A NE1   1 
ATOM   2556  C CE2   . TRP A 1 332 ? -65.787 -5.986  -12.740  1.00 45.58  ? 332 TRP A CE2   1 
ATOM   2557  C CE3   . TRP A 1 332 ? -63.547 -5.647  -11.912  1.00 42.17  ? 332 TRP A CE3   1 
ATOM   2558  C CZ2   . TRP A 1 332 ? -65.323 -6.502  -13.944  1.00 38.98  ? 332 TRP A CZ2   1 
ATOM   2559  C CZ3   . TRP A 1 332 ? -63.087 -6.140  -13.111  1.00 46.05  ? 332 TRP A CZ3   1 
ATOM   2560  C CH2   . TRP A 1 332 ? -63.962 -6.582  -14.100  1.00 44.46  ? 332 TRP A CH2   1 
ATOM   2561  N N     . THR A 1 333 ? -66.074 -1.327  -9.888   1.00 45.53  ? 333 THR A N     1 
ATOM   2562  C CA    . THR A 1 333 ? -66.802 -0.302  -10.630  1.00 50.23  ? 333 THR A CA    1 
ATOM   2563  C C     . THR A 1 333 ? -65.815 0.641   -11.316  1.00 47.74  ? 333 THR A C     1 
ATOM   2564  O O     . THR A 1 333 ? -65.958 0.938   -12.494  1.00 50.65  ? 333 THR A O     1 
ATOM   2565  C CB    . THR A 1 333 ? -67.832 0.442   -9.762   1.00 49.71  ? 333 THR A CB    1 
ATOM   2566  O OG1   . THR A 1 333 ? -68.778 -0.547  -9.374   1.00 49.15  ? 333 THR A OG1   1 
ATOM   2567  C CG2   . THR A 1 333 ? -68.567 1.565   -10.468  1.00 46.78  ? 333 THR A CG2   1 
ATOM   2568  N N     . ALA A 1 334 ? -64.785 1.068   -10.595  1.00 42.17  ? 334 ALA A N     1 
ATOM   2569  C CA    . ALA A 1 334 ? -63.765 1.927   -11.167  1.00 41.91  ? 334 ALA A CA    1 
ATOM   2570  C C     . ALA A 1 334 ? -62.979 1.228   -12.286  1.00 45.26  ? 334 ALA A C     1 
ATOM   2571  O O     . ALA A 1 334 ? -62.640 1.859   -13.290  1.00 44.39  ? 334 ALA A O     1 
ATOM   2572  C CB    . ALA A 1 334 ? -62.843 2.357   -10.061  1.00 42.76  ? 334 ALA A CB    1 
ATOM   2573  N N     . ILE A 1 335 ? -62.626 -0.054  -12.087  1.00 44.24  ? 335 ILE A N     1 
ATOM   2574  C CA    . ILE A 1 335 ? -61.801 -0.769  -13.050  1.00 44.29  ? 335 ILE A CA    1 
ATOM   2575  C C     . ILE A 1 335 ? -62.607 -1.007  -14.322  1.00 46.27  ? 335 ILE A C     1 
ATOM   2576  O O     . ILE A 1 335 ? -62.153 -0.683  -15.404  1.00 49.77  ? 335 ILE A O     1 
ATOM   2577  C CB    . ILE A 1 335 ? -61.245 -2.079  -12.458  1.00 45.37  ? 335 ILE A CB    1 
ATOM   2578  C CG1   . ILE A 1 335 ? -60.205 -1.797  -11.374  1.00 44.71  ? 335 ILE A CG1   1 
ATOM   2579  C CG2   . ILE A 1 335 ? -60.651 -2.956  -13.547  1.00 49.40  ? 335 ILE A CG2   1 
ATOM   2580  C CD1   . ILE A 1 335 ? -59.858 -2.980  -10.481  1.00 43.29  ? 335 ILE A CD1   1 
ATOM   2581  N N     . ARG A 1 336 ? -63.794 -1.609  -14.183  1.00 52.52  ? 336 ARG A N     1 
ATOM   2582  C CA    . ARG A 1 336 ? -64.620 -1.984  -15.317  1.00 46.02  ? 336 ARG A CA    1 
ATOM   2583  C C     . ARG A 1 336 ? -64.940 -0.764  -16.160  1.00 42.52  ? 336 ARG A C     1 
ATOM   2584  O O     . ARG A 1 336 ? -64.791 -0.809  -17.375  1.00 38.79  ? 336 ARG A O     1 
ATOM   2585  C CB    . ARG A 1 336 ? -65.936 -2.610  -14.852  1.00 54.88  ? 336 ARG A CB    1 
ATOM   2586  C CG    . ARG A 1 336 ? -66.786 -3.206  -15.966  1.00 53.72  ? 336 ARG A CG    1 
ATOM   2587  C CD    . ARG A 1 336 ? -68.259 -3.145  -15.609  1.00 58.76  ? 336 ARG A CD    1 
ATOM   2588  N NE    . ARG A 1 336 ? -68.974 -4.262  -16.202  1.00 62.03  ? 336 ARG A NE    1 
ATOM   2589  C CZ    . ARG A 1 336 ? -69.322 -4.338  -17.474  1.00 68.92  ? 336 ARG A CZ    1 
ATOM   2590  N NH1   . ARG A 1 336 ? -69.319 -3.245  -18.224  1.00 73.96  ? 336 ARG A NH1   1 
ATOM   2591  N NH2   . ARG A 1 336 ? -69.717 -5.500  -17.967  1.00 62.19  ? 336 ARG A NH2   1 
ATOM   2592  N N     . ASP A 1 337 ? -65.386 0.309   -15.499  1.00 46.97  ? 337 ASP A N     1 
ATOM   2593  C CA    . ASP A 1 337 ? -65.801 1.536   -16.168  1.00 48.99  ? 337 ASP A CA    1 
ATOM   2594  C C     . ASP A 1 337 ? -64.666 2.139   -16.984  1.00 49.50  ? 337 ASP A C     1 
ATOM   2595  O O     . ASP A 1 337 ? -64.957 2.754   -18.004  1.00 51.22  ? 337 ASP A O     1 
ATOM   2596  C CB    . ASP A 1 337 ? -66.348 2.570   -15.180  1.00 51.01  ? 337 ASP A CB    1 
ATOM   2597  C CG    . ASP A 1 337 ? -67.753 2.224   -14.711  1.00 62.92  ? 337 ASP A CG    1 
ATOM   2598  O OD1   . ASP A 1 337 ? -68.300 1.150   -15.153  1.00 74.17  ? 337 ASP A OD1   1 
ATOM   2599  O OD2   . ASP A 1 337 ? -68.271 2.979   -13.880  1.00 61.79  ? 337 ASP A OD2   1 
ATOM   2600  N N     . SER A 1 338 ? -63.407 1.925   -16.542  1.00 45.52  ? 338 SER A N     1 
ATOM   2601  C CA    . SER A 1 338 ? -62.221 2.397   -17.242  1.00 44.39  ? 338 SER A CA    1 
ATOM   2602  C C     . SER A 1 338 ? -62.041 1.740   -18.606  1.00 43.00  ? 338 SER A C     1 
ATOM   2603  O O     . SER A 1 338 ? -61.327 2.287   -19.452  1.00 39.60  ? 338 SER A O     1 
ATOM   2604  C CB    . SER A 1 338 ? -60.985 2.202   -16.422  1.00 44.45  ? 338 SER A CB    1 
ATOM   2605  O OG    . SER A 1 338 ? -61.066 2.963   -15.234  1.00 46.25  ? 338 SER A OG    1 
ATOM   2606  N N     . PHE A 1 339 ? -62.684 0.585   -18.806  1.00 44.04  ? 339 PHE A N     1 
ATOM   2607  C CA    . PHE A 1 339 ? -62.490 -0.192  -20.017  1.00 43.85  ? 339 PHE A CA    1 
ATOM   2608  C C     . PHE A 1 339 ? -63.764 -0.403  -20.838  1.00 39.27  ? 339 PHE A C     1 
ATOM   2609  O O     . PHE A 1 339 ? -63.632 -0.807  -21.986  1.00 43.84  ? 339 PHE A O     1 
ATOM   2610  C CB    . PHE A 1 339 ? -61.859 -1.536  -19.657  1.00 47.05  ? 339 PHE A CB    1 
ATOM   2611  C CG    . PHE A 1 339 ? -60.473 -1.397  -19.085  1.00 46.85  ? 339 PHE A CG    1 
ATOM   2612  C CD1   . PHE A 1 339 ? -59.400 -1.114  -19.910  1.00 43.05  ? 339 PHE A CD1   1 
ATOM   2613  C CD2   . PHE A 1 339 ? -60.254 -1.516  -17.721  1.00 46.41  ? 339 PHE A CD2   1 
ATOM   2614  C CE1   . PHE A 1 339 ? -58.129 -0.959  -19.382  1.00 47.31  ? 339 PHE A CE1   1 
ATOM   2615  C CE2   . PHE A 1 339 ? -58.984 -1.362  -17.199  1.00 48.88  ? 339 PHE A CE2   1 
ATOM   2616  C CZ    . PHE A 1 339 ? -57.924 -1.057  -18.025  1.00 46.93  ? 339 PHE A CZ    1 
ATOM   2617  N N     . ALA A 1 340 ? -64.955 -0.094  -20.303  1.00 41.17  ? 340 ALA A N     1 
ATOM   2618  C CA    . ALA A 1 340 ? -66.226 -0.462  -20.935  1.00 44.45  ? 340 ALA A CA    1 
ATOM   2619  C C     . ALA A 1 340 ? -66.411 0.092   -22.348  1.00 46.77  ? 340 ALA A C     1 
ATOM   2620  O O     . ALA A 1 340 ? -66.990 -0.589  -23.179  1.00 53.99  ? 340 ALA A O     1 
ATOM   2621  C CB    . ALA A 1 340 ? -67.394 -0.017  -20.111  1.00 43.25  ? 340 ALA A CB    1 
ATOM   2622  N N     . ASP A 1 341 ? -65.943 1.305   -22.643  1.00 45.93  ? 341 ASP A N     1 
ATOM   2623  C CA    . ASP A 1 341 ? -66.221 1.921   -23.932  1.00 45.97  ? 341 ASP A CA    1 
ATOM   2624  C C     . ASP A 1 341 ? -65.318 1.407   -25.065  1.00 45.50  ? 341 ASP A C     1 
ATOM   2625  O O     . ASP A 1 341 ? -65.311 1.991   -26.138  1.00 59.25  ? 341 ASP A O     1 
ATOM   2626  C CB    . ASP A 1 341 ? -66.111 3.447   -23.807  1.00 48.28  ? 341 ASP A CB    1 
ATOM   2627  C CG    . ASP A 1 341 ? -64.686 3.987   -23.722  1.00 57.08  ? 341 ASP A CG    1 
ATOM   2628  O OD1   . ASP A 1 341 ? -63.749 3.209   -23.467  1.00 55.66  ? 341 ASP A OD1   1 
ATOM   2629  O OD2   . ASP A 1 341 ? -64.510 5.191   -23.939  1.00 69.66  ? 341 ASP A OD2   1 
ATOM   2630  N N     . ILE A 1 342 ? -64.507 0.361   -24.875  1.00 48.44  ? 342 ILE A N     1 
ATOM   2631  C CA    . ILE A 1 342 ? -63.568 -0.071  -25.911  1.00 47.08  ? 342 ILE A CA    1 
ATOM   2632  C C     . ILE A 1 342 ? -64.214 -1.170  -26.748  1.00 51.53  ? 342 ILE A C     1 
ATOM   2633  O O     . ILE A 1 342 ? -64.427 -2.258  -26.220  1.00 46.85  ? 342 ILE A O     1 
ATOM   2634  C CB    . ILE A 1 342 ? -62.251 -0.618  -25.311  1.00 48.22  ? 342 ILE A CB    1 
ATOM   2635  C CG1   . ILE A 1 342 ? -61.494 0.429   -24.496  1.00 48.63  ? 342 ILE A CG1   1 
ATOM   2636  C CG2   . ILE A 1 342 ? -61.349 -1.252  -26.375  1.00 43.88  ? 342 ILE A CG2   1 
ATOM   2637  C CD1   . ILE A 1 342 ? -60.567 -0.159  -23.441  1.00 49.96  ? 342 ILE A CD1   1 
ATOM   2638  N N     . PRO A 1 343 ? -64.438 -0.976  -28.072  1.00 55.67  ? 343 PRO A N     1 
ATOM   2639  C CA    . PRO A 1 343 ? -65.062 -2.004  -28.911  1.00 49.52  ? 343 PRO A CA    1 
ATOM   2640  C C     . PRO A 1 343 ? -64.427 -3.390  -28.740  1.00 46.68  ? 343 PRO A C     1 
ATOM   2641  O O     . PRO A 1 343 ? -63.204 -3.561  -28.833  1.00 45.32  ? 343 PRO A O     1 
ATOM   2642  C CB    . PRO A 1 343 ? -64.839 -1.533  -30.369  1.00 49.95  ? 343 PRO A CB    1 
ATOM   2643  C CG    . PRO A 1 343 ? -64.373 -0.093  -30.305  1.00 53.68  ? 343 PRO A CG    1 
ATOM   2644  C CD    . PRO A 1 343 ? -64.050 0.214   -28.846  1.00 58.53  ? 343 PRO A CD    1 
ATOM   2645  N N     . GLY A 1 344 ? -65.271 -4.394  -28.493  1.00 39.51  ? 344 GLY A N     1 
ATOM   2646  C CA    . GLY A 1 344 ? -64.797 -5.768  -28.440  1.00 41.27  ? 344 GLY A CA    1 
ATOM   2647  C C     . GLY A 1 344 ? -64.435 -6.230  -27.030  1.00 45.65  ? 344 GLY A C     1 
ATOM   2648  O O     . GLY A 1 344 ? -64.206 -7.418  -26.825  1.00 46.25  ? 344 GLY A O     1 
ATOM   2649  N N     . VAL A 1 345 ? -64.393 -5.305  -26.060  1.00 43.40  ? 345 VAL A N     1 
ATOM   2650  C CA    . VAL A 1 345 ? -63.941 -5.652  -24.723  1.00 48.00  ? 345 VAL A CA    1 
ATOM   2651  C C     . VAL A 1 345 ? -64.869 -6.729  -24.151  1.00 47.13  ? 345 VAL A C     1 
ATOM   2652  O O     . VAL A 1 345 ? -66.088 -6.658  -24.334  1.00 50.66  ? 345 VAL A O     1 
ATOM   2653  C CB    . VAL A 1 345 ? -63.876 -4.395  -23.824  1.00 47.88  ? 345 VAL A CB    1 
ATOM   2654  C CG1   . VAL A 1 345 ? -65.268 -3.899  -23.428  1.00 46.57  ? 345 VAL A CG1   1 
ATOM   2655  C CG2   . VAL A 1 345 ? -63.020 -4.613  -22.586  1.00 45.78  ? 345 VAL A CG2   1 
ATOM   2656  N N     . LYS A 1 346 ? -64.302 -7.706  -23.432  1.00 43.04  ? 346 LYS A N     1 
ATOM   2657  C CA    . LYS A 1 346 ? -65.134 -8.651  -22.686  1.00 49.37  ? 346 LYS A CA    1 
ATOM   2658  C C     . LYS A 1 346 ? -64.636 -8.803  -21.242  1.00 51.30  ? 346 LYS A C     1 
ATOM   2659  O O     . LYS A 1 346 ? -63.424 -8.840  -20.999  1.00 53.19  ? 346 LYS A O     1 
ATOM   2660  C CB    . LYS A 1 346 ? -65.183 -9.994  -23.429  1.00 50.16  ? 346 LYS A CB    1 
ATOM   2661  C CG    . LYS A 1 346 ? -65.979 -9.997  -24.732  1.00 58.47  ? 346 LYS A CG    1 
ATOM   2662  C CD    . LYS A 1 346 ? -65.739 -11.228 -25.599  1.00 71.97  ? 346 LYS A CD    1 
ATOM   2663  C CE    . LYS A 1 346 ? -66.361 -11.142 -26.982  1.00 74.85  ? 346 LYS A CE    1 
ATOM   2664  N NZ    . LYS A 1 346 ? -65.528 -10.337 -27.920  1.00 79.50  ? 346 LYS A NZ    1 
ATOM   2665  N N     . PHE A 1 347 ? -65.579 -8.941  -20.288  1.00 54.29  ? 347 PHE A N     1 
ATOM   2666  C CA    . PHE A 1 347 ? -65.261 -9.070  -18.864  1.00 50.13  ? 347 PHE A CA    1 
ATOM   2667  C C     . PHE A 1 347 ? -65.673 -10.421 -18.289  1.00 44.18  ? 347 PHE A C     1 
ATOM   2668  O O     . PHE A 1 347 ? -66.836 -10.770 -18.334  1.00 47.04  ? 347 PHE A O     1 
ATOM   2669  C CB    . PHE A 1 347 ? -65.980 -8.010  -18.033  1.00 42.85  ? 347 PHE A CB    1 
ATOM   2670  C CG    . PHE A 1 347 ? -65.709 -6.599  -18.467  1.00 46.99  ? 347 PHE A CG    1 
ATOM   2671  C CD1   . PHE A 1 347 ? -66.418 -6.030  -19.512  1.00 52.06  ? 347 PHE A CD1   1 
ATOM   2672  C CD2   . PHE A 1 347 ? -64.698 -5.858  -17.870  1.00 51.20  ? 347 PHE A CD2   1 
ATOM   2673  C CE1   . PHE A 1 347 ? -66.170 -4.725  -19.912  1.00 52.33  ? 347 PHE A CE1   1 
ATOM   2674  C CE2   . PHE A 1 347 ? -64.449 -4.555  -18.270  1.00 49.64  ? 347 PHE A CE2   1 
ATOM   2675  C CZ    . PHE A 1 347 ? -65.194 -3.986  -19.282  1.00 53.37  ? 347 PHE A CZ    1 
ATOM   2676  N N     . TYR A 1 348 ? -64.737 -11.122 -17.649  1.00 44.85  ? 348 TYR A N     1 
ATOM   2677  C CA    . TYR A 1 348 ? -65.016 -12.431 -17.079  1.00 44.04  ? 348 TYR A CA    1 
ATOM   2678  C C     . TYR A 1 348 ? -64.581 -12.494 -15.612  1.00 45.24  ? 348 TYR A C     1 
ATOM   2679  O O     . TYR A 1 348 ? -63.483 -12.050 -15.273  1.00 46.09  ? 348 TYR A O     1 
ATOM   2680  C CB    . TYR A 1 348 ? -64.229 -13.517 -17.824  1.00 47.24  ? 348 TYR A CB    1 
ATOM   2681  C CG    . TYR A 1 348 ? -64.406 -13.604 -19.324  1.00 47.21  ? 348 TYR A CG    1 
ATOM   2682  C CD1   . TYR A 1 348 ? -63.769 -12.712 -20.175  1.00 45.58  ? 348 TYR A CD1   1 
ATOM   2683  C CD2   . TYR A 1 348 ? -65.199 -14.594 -19.900  1.00 43.37  ? 348 TYR A CD2   1 
ATOM   2684  C CE1   . TYR A 1 348 ? -63.889 -12.824 -21.555  1.00 46.00  ? 348 TYR A CE1   1 
ATOM   2685  C CE2   . TYR A 1 348 ? -65.364 -14.687 -21.274  1.00 42.40  ? 348 TYR A CE2   1 
ATOM   2686  C CZ    . TYR A 1 348 ? -64.697 -13.808 -22.112  1.00 45.51  ? 348 TYR A CZ    1 
ATOM   2687  O OH    . TYR A 1 348 ? -64.863 -13.875 -23.486  1.00 44.89  ? 348 TYR A OH    1 
ATOM   2688  N N     . PHE A 1 349 ? -65.437 -13.072 -14.757  1.00 44.30  ? 349 PHE A N     1 
ATOM   2689  C CA    . PHE A 1 349 ? -65.035 -13.665 -13.485  1.00 43.20  ? 349 PHE A CA    1 
ATOM   2690  C C     . PHE A 1 349 ? -64.936 -15.183 -13.672  1.00 45.18  ? 349 PHE A C     1 
ATOM   2691  O O     . PHE A 1 349 ? -65.297 -15.683 -14.735  1.00 46.82  ? 349 PHE A O     1 
ATOM   2692  C CB    . PHE A 1 349 ? -66.010 -13.219 -12.396  1.00 47.04  ? 349 PHE A CB    1 
ATOM   2693  C CG    . PHE A 1 349 ? -65.896 -11.760 -12.041  1.00 53.36  ? 349 PHE A CG    1 
ATOM   2694  C CD1   . PHE A 1 349 ? -64.824 -11.299 -11.288  1.00 64.98  ? 349 PHE A CD1   1 
ATOM   2695  C CD2   . PHE A 1 349 ? -66.828 -10.844 -12.483  1.00 57.90  ? 349 PHE A CD2   1 
ATOM   2696  C CE1   . PHE A 1 349 ? -64.703 -9.957  -10.968  1.00 61.98  ? 349 PHE A CE1   1 
ATOM   2697  C CE2   . PHE A 1 349 ? -66.701 -9.500  -12.167  1.00 62.61  ? 349 PHE A CE2   1 
ATOM   2698  C CZ    . PHE A 1 349 ? -65.640 -9.058  -11.414  1.00 61.53  ? 349 PHE A CZ    1 
ATOM   2699  N N     . PRO A 1 350 ? -64.409 -15.995 -12.717  1.00 46.01  ? 350 PRO A N     1 
ATOM   2700  C CA    . PRO A 1 350 ? -64.190 -17.427 -12.971  1.00 48.69  ? 350 PRO A CA    1 
ATOM   2701  C C     . PRO A 1 350 ? -65.461 -18.198 -13.340  1.00 47.42  ? 350 PRO A C     1 
ATOM   2702  O O     . PRO A 1 350 ? -65.401 -19.101 -14.161  1.00 47.94  ? 350 PRO A O     1 
ATOM   2703  C CB    . PRO A 1 350 ? -63.608 -17.946 -11.648  1.00 42.12  ? 350 PRO A CB    1 
ATOM   2704  C CG    . PRO A 1 350 ? -63.004 -16.722 -11.038  1.00 41.77  ? 350 PRO A CG    1 
ATOM   2705  C CD    . PRO A 1 350 ? -63.997 -15.626 -11.362  1.00 41.64  ? 350 PRO A CD    1 
ATOM   2706  N N     . GLU A 1 351 ? -66.592 -17.846 -12.715  1.00 46.74  ? 351 GLU A N     1 
ATOM   2707  C CA    . GLU A 1 351 ? -67.884 -18.463 -13.000  1.00 45.97  ? 351 GLU A CA    1 
ATOM   2708  C C     . GLU A 1 351 ? -68.220 -18.312 -14.474  1.00 46.19  ? 351 GLU A C     1 
ATOM   2709  O O     . GLU A 1 351 ? -68.848 -19.198 -15.014  1.00 52.44  ? 351 GLU A O     1 
ATOM   2710  C CB    . GLU A 1 351 ? -69.024 -17.868 -12.170  1.00 46.56  ? 351 GLU A CB    1 
ATOM   2711  C CG    . GLU A 1 351 ? -69.104 -16.327 -12.211  1.00 64.05  ? 351 GLU A CG    1 
ATOM   2712  C CD    . GLU A 1 351 ? -68.429 -15.540 -11.072  1.00 72.07  ? 351 GLU A CD    1 
ATOM   2713  O OE1   . GLU A 1 351 ? -67.385 -16.017 -10.516  1.00 61.20  ? 351 GLU A OE1   1 
ATOM   2714  O OE2   . GLU A 1 351 ? -68.916 -14.413 -10.748  1.00 62.36  ? 351 GLU A OE2   1 
ATOM   2715  N N     . ASP A 1 352 ? -67.803 -17.217 -15.124  1.00 50.84  ? 352 ASP A N     1 
ATOM   2716  C CA    . ASP A 1 352 ? -68.186 -16.954 -16.505  1.00 51.53  ? 352 ASP A CA    1 
ATOM   2717  C C     . ASP A 1 352 ? -67.193 -17.553 -17.505  1.00 51.47  ? 352 ASP A C     1 
ATOM   2718  O O     . ASP A 1 352 ? -67.293 -17.261 -18.694  1.00 54.39  ? 352 ASP A O     1 
ATOM   2719  C CB    . ASP A 1 352 ? -68.277 -15.460 -16.847  1.00 58.42  ? 352 ASP A CB    1 
ATOM   2720  C CG    . ASP A 1 352 ? -68.939 -14.545 -15.834  1.00 61.42  ? 352 ASP A CG    1 
ATOM   2721  O OD1   . ASP A 1 352 ? -70.141 -14.747 -15.530  1.00 64.37  ? 352 ASP A OD1   1 
ATOM   2722  O OD2   . ASP A 1 352 ? -68.249 -13.599 -15.396  1.00 58.52  ? 352 ASP A OD2   1 
ATOM   2723  N N     . ARG A 1 353 ? -66.237 -18.387 -17.061  1.00 52.51  ? 353 ARG A N     1 
ATOM   2724  C CA    . ARG A 1 353 ? -65.320 -19.040 -17.984  1.00 48.49  ? 353 ARG A CA    1 
ATOM   2725  C C     . ARG A 1 353 ? -65.871 -20.428 -18.312  1.00 51.88  ? 353 ARG A C     1 
ATOM   2726  O O     . ARG A 1 353 ? -66.081 -21.240 -17.433  1.00 46.52  ? 353 ARG A O     1 
ATOM   2727  C CB    . ARG A 1 353 ? -63.909 -19.092 -17.397  1.00 47.03  ? 353 ARG A CB    1 
ATOM   2728  C CG    . ARG A 1 353 ? -63.306 -17.718 -17.124  1.00 45.80  ? 353 ARG A CG    1 
ATOM   2729  C CD    . ARG A 1 353 ? -63.113 -16.934 -18.410  1.00 45.59  ? 353 ARG A CD    1 
ATOM   2730  N NE    . ARG A 1 353 ? -62.031 -17.504 -19.206  1.00 45.43  ? 353 ARG A NE    1 
ATOM   2731  C CZ    . ARG A 1 353 ? -61.738 -17.136 -20.441  1.00 43.50  ? 353 ARG A CZ    1 
ATOM   2732  N NH1   . ARG A 1 353 ? -62.391 -16.139 -21.002  1.00 54.01  ? 353 ARG A NH1   1 
ATOM   2733  N NH2   . ARG A 1 353 ? -60.758 -17.718 -21.097  1.00 41.98  ? 353 ARG A NH2   1 
ATOM   2734  N N     . ARG A 1 354 ? -66.118 -20.715 -19.588  1.00 48.10  ? 354 ARG A N     1 
ATOM   2735  C CA    . ARG A 1 354 ? -66.887 -21.901 -19.910  1.00 48.94  ? 354 ARG A CA    1 
ATOM   2736  C C     . ARG A 1 354 ? -65.975 -23.117 -19.982  1.00 45.67  ? 354 ARG A C     1 
ATOM   2737  O O     . ARG A 1 354 ? -66.476 -24.219 -19.955  1.00 50.62  ? 354 ARG A O     1 
ATOM   2738  C CB    . ARG A 1 354 ? -67.708 -21.712 -21.194  1.00 45.88  ? 354 ARG A CB    1 
ATOM   2739  C CG    . ARG A 1 354 ? -66.899 -21.465 -22.460  1.00 41.90  ? 354 ARG A CG    1 
ATOM   2740  C CD    . ARG A 1 354 ? -67.832 -20.973 -23.549  1.00 41.75  ? 354 ARG A CD    1 
ATOM   2741  N NE    . ARG A 1 354 ? -67.084 -20.569 -24.721  1.00 48.02  ? 354 ARG A NE    1 
ATOM   2742  C CZ    . ARG A 1 354 ? -66.482 -21.402 -25.551  1.00 51.49  ? 354 ARG A CZ    1 
ATOM   2743  N NH1   . ARG A 1 354 ? -66.854 -22.670 -25.614  1.00 62.01  ? 354 ARG A NH1   1 
ATOM   2744  N NH2   . ARG A 1 354 ? -65.523 -20.950 -26.333  1.00 54.71  ? 354 ARG A NH2   1 
ATOM   2745  N N     . HIS A 1 355 ? -64.662 -22.922 -20.100  1.00 49.19  ? 355 HIS A N     1 
ATOM   2746  C CA    . HIS A 1 355 ? -63.711 -24.017 -20.039  1.00 42.51  ? 355 HIS A CA    1 
ATOM   2747  C C     . HIS A 1 355 ? -63.291 -24.273 -18.590  1.00 51.18  ? 355 HIS A C     1 
ATOM   2748  O O     . HIS A 1 355 ? -63.162 -23.357 -17.782  1.00 62.02  ? 355 HIS A O     1 
ATOM   2749  C CB    . HIS A 1 355 ? -62.461 -23.705 -20.859  1.00 43.32  ? 355 HIS A CB    1 
ATOM   2750  C CG    . HIS A 1 355 ? -62.700 -23.455 -22.307  1.00 49.63  ? 355 HIS A CG    1 
ATOM   2751  N ND1   . HIS A 1 355 ? -62.440 -24.416 -23.267  1.00 51.40  ? 355 HIS A ND1   1 
ATOM   2752  C CD2   . HIS A 1 355 ? -63.160 -22.379 -22.964  1.00 42.95  ? 355 HIS A CD2   1 
ATOM   2753  C CE1   . HIS A 1 355 ? -62.735 -23.914 -24.458  1.00 47.93  ? 355 HIS A CE1   1 
ATOM   2754  N NE2   . HIS A 1 355 ? -63.160 -22.680 -24.298  1.00 44.27  ? 355 HIS A NE2   1 
ATOM   2755  N N     . LYS A 1 356 ? -63.068 -25.545 -18.267  1.00 50.57  ? 356 LYS A N     1 
ATOM   2756  C CA    . LYS A 1 356 ? -62.725 -25.960 -16.926  1.00 53.30  ? 356 LYS A CA    1 
ATOM   2757  C C     . LYS A 1 356 ? -61.214 -26.121 -16.837  1.00 49.40  ? 356 LYS A C     1 
ATOM   2758  O O     . LYS A 1 356 ? -60.696 -26.335 -15.752  1.00 48.93  ? 356 LYS A O     1 
ATOM   2759  C CB    . LYS A 1 356 ? -63.471 -27.252 -16.595  1.00 60.68  ? 356 LYS A CB    1 
ATOM   2760  C CG    . LYS A 1 356 ? -64.975 -27.077 -16.479  1.00 73.28  ? 356 LYS A CG    1 
ATOM   2761  C CD    . LYS A 1 356 ? -65.733 -28.371 -16.245  1.00 82.85  ? 356 LYS A CD    1 
ATOM   2762  C CE    . LYS A 1 356 ? -65.445 -29.019 -14.906  1.00 78.20  ? 356 LYS A CE    1 
ATOM   2763  N NZ    . LYS A 1 356 ? -66.550 -29.926 -14.534  1.00 76.92  ? 356 LYS A NZ    1 
ATOM   2764  N N     . VAL A 1 357 ? -60.527 -26.044 -17.984  1.00 45.62  ? 357 VAL A N     1 
ATOM   2765  C CA    . VAL A 1 357 ? -59.078 -25.854 -18.031  1.00 45.70  ? 357 VAL A CA    1 
ATOM   2766  C C     . VAL A 1 357 ? -58.811 -24.534 -18.778  1.00 48.88  ? 357 VAL A C     1 
ATOM   2767  O O     . VAL A 1 357 ? -58.888 -24.430 -20.012  1.00 50.24  ? 357 VAL A O     1 
ATOM   2768  C CB    . VAL A 1 357 ? -58.341 -27.081 -18.625  1.00 46.44  ? 357 VAL A CB    1 
ATOM   2769  C CG1   . VAL A 1 357 ? -56.844 -26.865 -18.781  1.00 51.75  ? 357 VAL A CG1   1 
ATOM   2770  C CG2   . VAL A 1 357 ? -58.560 -28.329 -17.787  1.00 45.03  ? 357 VAL A CG2   1 
ATOM   2771  N N     . ASP A 1 358 ? -58.520 -23.496 -17.997  1.00 43.01  ? 358 ASP A N     1 
ATOM   2772  C CA    . ASP A 1 358 ? -58.663 -22.144 -18.495  1.00 48.18  ? 358 ASP A CA    1 
ATOM   2773  C C     . ASP A 1 358 ? -57.606 -21.258 -17.858  1.00 56.18  ? 358 ASP A C     1 
ATOM   2774  O O     . ASP A 1 358 ? -57.198 -21.487 -16.710  1.00 52.27  ? 358 ASP A O     1 
ATOM   2775  C CB    . ASP A 1 358 ? -60.044 -21.575 -18.186  1.00 43.89  ? 358 ASP A CB    1 
ATOM   2776  C CG    . ASP A 1 358 ? -60.377 -20.247 -18.839  1.00 45.32  ? 358 ASP A CG    1 
ATOM   2777  O OD1   . ASP A 1 358 ? -60.734 -20.239 -20.040  1.00 42.18  ? 358 ASP A OD1   1 
ATOM   2778  O OD2   . ASP A 1 358 ? -60.294 -19.222 -18.143  1.00 58.33  ? 358 ASP A OD2   1 
ATOM   2779  N N     . LEU A 1 359 ? -57.200 -20.246 -18.638  1.00 52.62  ? 359 LEU A N     1 
ATOM   2780  C CA    . LEU A 1 359 ? -56.219 -19.275 -18.197  1.00 50.14  ? 359 LEU A CA    1 
ATOM   2781  C C     . LEU A 1 359 ? -56.602 -18.695 -16.837  1.00 43.41  ? 359 LEU A C     1 
ATOM   2782  O O     . LEU A 1 359 ? -55.780 -18.648 -15.928  1.00 39.99  ? 359 LEU A O     1 
ATOM   2783  C CB    . LEU A 1 359 ? -56.128 -18.140 -19.219  1.00 53.84  ? 359 LEU A CB    1 
ATOM   2784  C CG    . LEU A 1 359 ? -55.315 -16.958 -18.705  1.00 55.24  ? 359 LEU A CG    1 
ATOM   2785  C CD1   . LEU A 1 359 ? -53.836 -17.208 -18.931  1.00 56.99  ? 359 LEU A CD1   1 
ATOM   2786  C CD2   . LEU A 1 359 ? -55.781 -15.683 -19.346  1.00 59.75  ? 359 LEU A CD2   1 
ATOM   2787  N N     . LEU A 1 360 ? -57.838 -18.208 -16.720  1.00 36.37  ? 360 LEU A N     1 
ATOM   2788  C CA    . LEU A 1 360 ? -58.227 -17.505 -15.511  1.00 44.02  ? 360 LEU A CA    1 
ATOM   2789  C C     . LEU A 1 360 ? -58.175 -18.427 -14.293  1.00 41.65  ? 360 LEU A C     1 
ATOM   2790  O O     . LEU A 1 360 ? -57.967 -17.985 -13.176  1.00 48.04  ? 360 LEU A O     1 
ATOM   2791  C CB    . LEU A 1 360 ? -59.624 -16.888 -15.688  1.00 44.24  ? 360 LEU A CB    1 
ATOM   2792  C CG    . LEU A 1 360 ? -60.077 -16.028 -14.513  1.00 45.12  ? 360 LEU A CG    1 
ATOM   2793  C CD1   . LEU A 1 360 ? -58.993 -15.020 -14.154  1.00 49.53  ? 360 LEU A CD1   1 
ATOM   2794  C CD2   . LEU A 1 360 ? -61.375 -15.301 -14.806  1.00 44.13  ? 360 LEU A CD2   1 
ATOM   2795  N N     . LEU A 1 361 ? -58.437 -19.712 -14.475  1.00 51.07  ? 361 LEU A N     1 
ATOM   2796  C CA    . LEU A 1 361 ? -58.484 -20.594 -13.329  1.00 52.80  ? 361 LEU A CA    1 
ATOM   2797  C C     . LEU A 1 361 ? -57.061 -20.980 -12.955  1.00 52.42  ? 361 LEU A C     1 
ATOM   2798  O O     . LEU A 1 361 ? -56.797 -21.234 -11.789  1.00 46.19  ? 361 LEU A O     1 
ATOM   2799  C CB    . LEU A 1 361 ? -59.361 -21.799 -13.648  1.00 53.26  ? 361 LEU A CB    1 
ATOM   2800  C CG    . LEU A 1 361 ? -60.768 -21.466 -14.137  1.00 59.45  ? 361 LEU A CG    1 
ATOM   2801  C CD1   . LEU A 1 361 ? -61.603 -22.734 -14.226  1.00 70.36  ? 361 LEU A CD1   1 
ATOM   2802  C CD2   . LEU A 1 361 ? -61.448 -20.452 -13.250  1.00 58.24  ? 361 LEU A CD2   1 
ATOM   2803  N N     . HIS A 1 362 ? -56.134 -20.950 -13.923  1.00 59.93  ? 362 HIS A N     1 
ATOM   2804  C CA    . HIS A 1 362 ? -54.729 -21.113 -13.575  1.00 60.54  ? 362 HIS A CA    1 
ATOM   2805  C C     . HIS A 1 362 ? -54.231 -19.922 -12.742  1.00 61.33  ? 362 HIS A C     1 
ATOM   2806  O O     . HIS A 1 362 ? -53.570 -20.134 -11.723  1.00 62.85  ? 362 HIS A O     1 
ATOM   2807  C CB    . HIS A 1 362 ? -53.843 -21.399 -14.787  1.00 54.08  ? 362 HIS A CB    1 
ATOM   2808  C CG    . HIS A 1 362 ? -52.388 -21.270 -14.429  1.00 81.05  ? 362 HIS A CG    1 
ATOM   2809  N ND1   . HIS A 1 362 ? -51.505 -20.408 -15.055  1.00 85.99  ? 362 HIS A ND1   1 
ATOM   2810  C CD2   . HIS A 1 362 ? -51.676 -21.864 -13.451  1.00 89.38  ? 362 HIS A CD2   1 
ATOM   2811  C CE1   . HIS A 1 362 ? -50.306 -20.499 -14.494  1.00 77.20  ? 362 HIS A CE1   1 
ATOM   2812  N NE2   . HIS A 1 362 ? -50.388 -21.385 -13.523  1.00 86.60  ? 362 HIS A NE2   1 
ATOM   2813  N N     . ARG A 1 363 ? -54.561 -18.686 -13.159  1.00 53.63  ? 363 ARG A N     1 
ATOM   2814  C CA    . ARG A 1 363 ? -53.942 -17.483 -12.604  1.00 59.00  ? 363 ARG A CA    1 
ATOM   2815  C C     . ARG A 1 363 ? -54.644 -16.976 -11.336  1.00 54.48  ? 363 ARG A C     1 
ATOM   2816  O O     . ARG A 1 363 ? -54.028 -16.252 -10.558  1.00 51.05  ? 363 ARG A O     1 
ATOM   2817  C CB    . ARG A 1 363 ? -53.819 -16.380 -13.663  1.00 57.31  ? 363 ARG A CB    1 
ATOM   2818  C CG    . ARG A 1 363 ? -52.417 -16.297 -14.247  1.00 63.59  ? 363 ARG A CG    1 
ATOM   2819  C CD    . ARG A 1 363 ? -52.445 -15.541 -15.547  1.00 80.54  ? 363 ARG A CD    1 
ATOM   2820  N NE    . ARG A 1 363 ? -51.201 -15.650 -16.289  1.00 93.04  ? 363 ARG A NE    1 
ATOM   2821  C CZ    . ARG A 1 363 ? -50.709 -16.760 -16.825  1.00 98.07  ? 363 ARG A CZ    1 
ATOM   2822  N NH1   . ARG A 1 363 ? -51.311 -17.921 -16.651  1.00 119.98 ? 363 ARG A NH1   1 
ATOM   2823  N NH2   . ARG A 1 363 ? -49.601 -16.707 -17.543  1.00 105.78 ? 363 ARG A NH2   1 
ATOM   2824  N N     . ALA A 1 364 ? -55.906 -17.358 -11.126  1.00 48.00  ? 364 ALA A N     1 
ATOM   2825  C CA    . ALA A 1 364 ? -56.541 -17.272 -9.821   1.00 53.21  ? 364 ALA A CA    1 
ATOM   2826  C C     . ALA A 1 364 ? -55.671 -17.921 -8.739   1.00 48.13  ? 364 ALA A C     1 
ATOM   2827  O O     . ALA A 1 364 ? -55.557 -17.387 -7.647   1.00 56.39  ? 364 ALA A O     1 
ATOM   2828  C CB    . ALA A 1 364 ? -57.929 -17.880 -9.864   1.00 48.65  ? 364 ALA A CB    1 
ATOM   2829  N N     . GLU A 1 365 ? -55.018 -19.041 -9.029   1.00 46.93  ? 365 GLU A N     1 
ATOM   2830  C CA    . GLU A 1 365 ? -54.177 -19.668 -8.026   1.00 53.61  ? 365 GLU A CA    1 
ATOM   2831  C C     . GLU A 1 365 ? -52.959 -18.787 -7.765   1.00 50.17  ? 365 GLU A C     1 
ATOM   2832  O O     . GLU A 1 365 ? -52.555 -18.625 -6.619   1.00 53.10  ? 365 GLU A O     1 
ATOM   2833  C CB    . GLU A 1 365 ? -53.746 -21.082 -8.437   1.00 59.58  ? 365 GLU A CB    1 
ATOM   2834  C CG    . GLU A 1 365 ? -54.903 -22.065 -8.688   1.00 67.98  ? 365 GLU A CG    1 
ATOM   2835  C CD    . GLU A 1 365 ? -55.651 -22.642 -7.485   1.00 72.92  ? 365 GLU A CD    1 
ATOM   2836  O OE1   . GLU A 1 365 ? -55.894 -23.874 -7.480   1.00 84.25  ? 365 GLU A OE1   1 
ATOM   2837  O OE2   . GLU A 1 365 ? -56.039 -21.872 -6.578   1.00 62.29  ? 365 GLU A OE2   1 
ATOM   2838  N N     . THR A 1 366 ? -52.368 -18.225 -8.827   1.00 45.88  ? 366 THR A N     1 
ATOM   2839  C CA    . THR A 1 366 ? -51.129 -17.470 -8.684   1.00 45.24  ? 366 THR A CA    1 
ATOM   2840  C C     . THR A 1 366 ? -51.361 -16.162 -7.923   1.00 41.09  ? 366 THR A C     1 
ATOM   2841  O O     . THR A 1 366 ? -50.514 -15.692 -7.152   1.00 33.31  ? 366 THR A O     1 
ATOM   2842  C CB    . THR A 1 366 ? -50.505 -17.179 -10.053  1.00 46.90  ? 366 THR A CB    1 
ATOM   2843  O OG1   . THR A 1 366 ? -50.429 -18.358 -10.846  1.00 44.43  ? 366 THR A OG1   1 
ATOM   2844  C CG2   . THR A 1 366 ? -49.092 -16.673 -9.914   1.00 51.15  ? 366 THR A CG2   1 
ATOM   2845  N N     . MET A 1 367 ? -52.537 -15.569 -8.156   1.00 35.99  ? 367 MET A N     1 
ATOM   2846  C CA    . MET A 1 367 ? -52.821 -14.243 -7.664   1.00 33.07  ? 367 MET A CA    1 
ATOM   2847  C C     . MET A 1 367 ? -53.303 -14.326 -6.222   1.00 34.22  ? 367 MET A C     1 
ATOM   2848  O O     . MET A 1 367 ? -53.488 -13.272 -5.610   1.00 37.31  ? 367 MET A O     1 
ATOM   2849  C CB    . MET A 1 367 ? -53.806 -13.502 -8.580   1.00 34.92  ? 367 MET A CB    1 
ATOM   2850  C CG    . MET A 1 367 ? -53.145 -13.068 -9.901   1.00 37.57  ? 367 MET A CG    1 
ATOM   2851  S SD    . MET A 1 367 ? -54.166 -12.014 -11.003  1.00 41.54  ? 367 MET A SD    1 
ATOM   2852  C CE    . MET A 1 367 ? -55.579 -13.087 -11.291  1.00 46.52  ? 367 MET A CE    1 
ATOM   2853  N N     . LYS A 1 368 ? -53.421 -15.546 -5.644   1.00 37.50  ? 368 LYS A N     1 
ATOM   2854  C CA    . LYS A 1 368 ? -53.584 -15.669 -4.194   1.00 39.81  ? 368 LYS A CA    1 
ATOM   2855  C C     . LYS A 1 368 ? -52.459 -16.481 -3.560   1.00 38.43  ? 368 LYS A C     1 
ATOM   2856  O O     . LYS A 1 368 ? -52.598 -17.003 -2.457   1.00 41.31  ? 368 LYS A O     1 
ATOM   2857  C CB    . LYS A 1 368 ? -54.964 -16.198 -3.813   1.00 47.84  ? 368 LYS A CB    1 
ATOM   2858  C CG    . LYS A 1 368 ? -55.267 -17.657 -4.106   1.00 58.72  ? 368 LYS A CG    1 
ATOM   2859  C CD    . LYS A 1 368 ? -56.605 -18.101 -3.545   1.00 62.29  ? 368 LYS A CD    1 
ATOM   2860  C CE    . LYS A 1 368 ? -56.915 -19.537 -3.906   1.00 72.32  ? 368 LYS A CE    1 
ATOM   2861  N NZ    . LYS A 1 368 ? -57.969 -20.108 -3.031   1.00 82.14  ? 368 LYS A NZ    1 
ATOM   2862  N N     . GLY A 1 369 ? -51.301 -16.499 -4.218   1.00 37.25  ? 369 GLY A N     1 
ATOM   2863  C CA    . GLY A 1 369 ? -50.080 -16.975 -3.583   1.00 41.37  ? 369 GLY A CA    1 
ATOM   2864  C C     . GLY A 1 369 ? -49.985 -18.493 -3.474   1.00 40.89  ? 369 GLY A C     1 
ATOM   2865  O O     . GLY A 1 369 ? -49.343 -18.988 -2.563   1.00 46.13  ? 369 GLY A O     1 
ATOM   2866  N N     . VAL A 1 370 ? -50.598 -19.210 -4.421   1.00 44.26  ? 370 VAL A N     1 
ATOM   2867  C CA    . VAL A 1 370 ? -50.537 -20.660 -4.449   1.00 45.56  ? 370 VAL A CA    1 
ATOM   2868  C C     . VAL A 1 370 ? -49.502 -21.046 -5.497   1.00 43.04  ? 370 VAL A C     1 
ATOM   2869  O O     . VAL A 1 370 ? -49.708 -20.831 -6.688   1.00 44.69  ? 370 VAL A O     1 
ATOM   2870  C CB    . VAL A 1 370 ? -51.913 -21.343 -4.699   1.00 50.54  ? 370 VAL A CB    1 
ATOM   2871  C CG1   . VAL A 1 370 ? -51.793 -22.854 -4.770   1.00 49.90  ? 370 VAL A CG1   1 
ATOM   2872  C CG2   . VAL A 1 370 ? -52.964 -21.010 -3.635   1.00 47.25  ? 370 VAL A CG2   1 
ATOM   2873  N N     . PRO A 1 371 ? -48.377 -21.671 -5.081   1.00 43.13  ? 371 PRO A N     1 
ATOM   2874  C CA    . PRO A 1 371 ? -47.330 -22.074 -6.010   1.00 48.22  ? 371 PRO A CA    1 
ATOM   2875  C C     . PRO A 1 371 ? -47.799 -23.307 -6.775   1.00 48.29  ? 371 PRO A C     1 
ATOM   2876  O O     . PRO A 1 371 ? -48.493 -24.124 -6.190   1.00 48.47  ? 371 PRO A O     1 
ATOM   2877  C CB    . PRO A 1 371 ? -46.155 -22.395 -5.083   1.00 43.65  ? 371 PRO A CB    1 
ATOM   2878  C CG    . PRO A 1 371 ? -46.822 -22.935 -3.843   1.00 43.58  ? 371 PRO A CG    1 
ATOM   2879  C CD    . PRO A 1 371 ? -48.085 -22.110 -3.705   1.00 45.63  ? 371 PRO A CD    1 
ATOM   2880  N N     . LYS A 1 372 ? -47.396 -23.398 -8.051   1.00 59.86  ? 372 LYS A N     1 
ATOM   2881  C CA    . LYS A 1 372 ? -47.928 -24.322 -9.049   1.00 62.83  ? 372 LYS A CA    1 
ATOM   2882  C C     . LYS A 1 372 ? -46.922 -24.412 -10.200  1.00 69.81  ? 372 LYS A C     1 
ATOM   2883  O O     . LYS A 1 372 ? -46.143 -23.484 -10.415  1.00 73.27  ? 372 LYS A O     1 
ATOM   2884  C CB    . LYS A 1 372 ? -49.309 -23.876 -9.553   1.00 59.47  ? 372 LYS A CB    1 
ATOM   2885  C CG    . LYS A 1 372 ? -50.508 -24.267 -8.690   1.00 60.10  ? 372 LYS A CG    1 
ATOM   2886  C CD    . LYS A 1 372 ? -50.868 -25.750 -8.798   1.00 69.34  ? 372 LYS A CD    1 
ATOM   2887  C CE    . LYS A 1 372 ? -51.593 -26.315 -7.592   1.00 77.84  ? 372 LYS A CE    1 
ATOM   2888  N NZ    . LYS A 1 372 ? -52.982 -25.810 -7.488   1.00 79.99  ? 372 LYS A NZ    1 
ATOM   2889  N N     . LEU A 1 373 ? -46.955 -25.541 -10.933  1.00 90.50  ? 373 LEU A N     1 
ATOM   2890  C CA    . LEU A 1 373 ? -45.947 -25.909 -11.928  1.00 87.56  ? 373 LEU A CA    1 
ATOM   2891  C C     . LEU A 1 373 ? -46.359 -25.471 -13.337  1.00 80.41  ? 373 LEU A C     1 
ATOM   2892  O O     . LEU A 1 373 ? -45.517 -25.313 -14.226  1.00 74.42  ? 373 LEU A O     1 
ATOM   2893  C CB    . LEU A 1 373 ? -45.782 -27.430 -11.859  1.00 89.77  ? 373 LEU A CB    1 
ATOM   2894  C CG    . LEU A 1 373 ? -45.245 -27.948 -10.526  1.00 100.21 ? 373 LEU A CG    1 
ATOM   2895  C CD1   . LEU A 1 373 ? -45.579 -29.421 -10.312  1.00 108.49 ? 373 LEU A CD1   1 
ATOM   2896  C CD2   . LEU A 1 373 ? -43.741 -27.719 -10.452  1.00 102.45 ? 373 LEU A CD2   1 
ATOM   2897  N N     . THR A 1 374 ? -47.660 -25.192 -13.495  1.00 84.52  ? 374 THR A N     1 
ATOM   2898  C CA    . THR A 1 374 ? -48.367 -25.258 -14.765  1.00 86.27  ? 374 THR A CA    1 
ATOM   2899  C C     . THR A 1 374 ? -48.135 -24.021 -15.646  1.00 85.27  ? 374 THR A C     1 
ATOM   2900  O O     . THR A 1 374 ? -48.554 -24.029 -16.803  1.00 85.87  ? 374 THR A O     1 
ATOM   2901  C CB    . THR A 1 374 ? -49.860 -25.537 -14.509  1.00 88.71  ? 374 THR A CB    1 
ATOM   2902  O OG1   . THR A 1 374 ? -50.419 -24.443 -13.783  1.00 87.07  ? 374 THR A OG1   1 
ATOM   2903  C CG2   . THR A 1 374 ? -50.116 -26.827 -13.747  1.00 87.75  ? 374 THR A CG2   1 
ATOM   2904  N N     . GLU A 1 375 ? -47.465 -22.965 -15.150  1.00 86.47  ? 375 GLU A N     1 
ATOM   2905  C CA    . GLU A 1 375 ? -47.095 -21.862 -16.033  1.00 88.51  ? 375 GLU A CA    1 
ATOM   2906  C C     . GLU A 1 375 ? -46.074 -22.331 -17.066  1.00 87.58  ? 375 GLU A C     1 
ATOM   2907  O O     . GLU A 1 375 ? -46.112 -21.886 -18.211  1.00 94.41  ? 375 GLU A O     1 
ATOM   2908  C CB    . GLU A 1 375 ? -46.484 -20.661 -15.312  1.00 81.76  ? 375 GLU A CB    1 
ATOM   2909  C CG    . GLU A 1 375 ? -45.933 -19.591 -16.282  1.00 82.50  ? 375 GLU A CG    1 
ATOM   2910  C CD    . GLU A 1 375 ? -46.920 -18.633 -16.947  1.00 75.10  ? 375 GLU A CD    1 
ATOM   2911  O OE1   . GLU A 1 375 ? -48.047 -18.472 -16.420  1.00 87.04  ? 375 GLU A OE1   1 
ATOM   2912  O OE2   . GLU A 1 375 ? -46.567 -18.042 -17.995  1.00 62.59  ? 375 GLU A OE2   1 
ATOM   2913  N N     . PHE A 1 376 ? -45.194 -23.257 -16.658  1.00 85.96  ? 376 PHE A N     1 
ATOM   2914  C CA    . PHE A 1 376 ? -44.096 -23.732 -17.489  1.00 73.28  ? 376 PHE A CA    1 
ATOM   2915  C C     . PHE A 1 376 ? -44.593 -24.366 -18.787  1.00 61.39  ? 376 PHE A C     1 
ATOM   2916  O O     . PHE A 1 376 ? -43.782 -24.833 -19.575  1.00 61.11  ? 376 PHE A O     1 
ATOM   2917  C CB    . PHE A 1 376 ? -43.209 -24.671 -16.668  1.00 77.52  ? 376 PHE A CB    1 
ATOM   2918  C CG    . PHE A 1 376 ? -42.132 -23.920 -15.930  1.00 85.55  ? 376 PHE A CG    1 
ATOM   2919  C CD1   . PHE A 1 376 ? -42.463 -22.884 -15.067  1.00 82.78  ? 376 PHE A CD1   1 
ATOM   2920  C CD2   . PHE A 1 376 ? -40.791 -24.184 -16.174  1.00 92.66  ? 376 PHE A CD2   1 
ATOM   2921  C CE1   . PHE A 1 376 ? -41.477 -22.164 -14.423  1.00 85.99  ? 376 PHE A CE1   1 
ATOM   2922  C CE2   . PHE A 1 376 ? -39.801 -23.460 -15.535  1.00 87.44  ? 376 PHE A CE2   1 
ATOM   2923  C CZ    . PHE A 1 376 ? -40.150 -22.460 -14.652  1.00 99.24  ? 376 PHE A CZ    1 
ATOM   2924  N N     . ASN A 1 377 ? -45.914 -24.323 -19.007  1.00 61.70  ? 377 ASN A N     1 
ATOM   2925  C CA    . ASN A 1 377 ? -46.579 -24.979 -20.118  1.00 65.15  ? 377 ASN A CA    1 
ATOM   2926  C C     . ASN A 1 377 ? -46.307 -24.205 -21.408  1.00 57.17  ? 377 ASN A C     1 
ATOM   2927  O O     . ASN A 1 377 ? -46.269 -24.800 -22.485  1.00 51.68  ? 377 ASN A O     1 
ATOM   2928  C CB    . ASN A 1 377 ? -48.090 -25.137 -19.867  1.00 70.39  ? 377 ASN A CB    1 
ATOM   2929  C CG    . ASN A 1 377 ? -48.484 -26.269 -18.927  1.00 74.58  ? 377 ASN A CG    1 
ATOM   2930  O OD1   . ASN A 1 377 ? -47.665 -27.057 -18.451  1.00 68.59  ? 377 ASN A OD1   1 
ATOM   2931  N ND2   . ASN A 1 377 ? -49.771 -26.359 -18.643  1.00 71.47  ? 377 ASN A ND2   1 
ATOM   2932  N N     . PHE A 1 378 ? -46.098 -22.887 -21.298  1.00 50.97  ? 378 PHE A N     1 
ATOM   2933  C CA    . PHE A 1 378 ? -45.801 -22.104 -22.485  1.00 54.00  ? 378 PHE A CA    1 
ATOM   2934  C C     . PHE A 1 378 ? -44.525 -22.631 -23.136  1.00 49.32  ? 378 PHE A C     1 
ATOM   2935  O O     . PHE A 1 378 ? -44.354 -22.457 -24.335  1.00 51.68  ? 378 PHE A O     1 
ATOM   2936  C CB    . PHE A 1 378 ? -45.787 -20.596 -22.205  1.00 52.97  ? 378 PHE A CB    1 
ATOM   2937  C CG    . PHE A 1 378 ? -44.565 -20.030 -21.538  1.00 53.15  ? 378 PHE A CG    1 
ATOM   2938  C CD1   . PHE A 1 378 ? -43.354 -19.963 -22.207  1.00 50.49  ? 378 PHE A CD1   1 
ATOM   2939  C CD2   . PHE A 1 378 ? -44.651 -19.486 -20.261  1.00 55.73  ? 378 PHE A CD2   1 
ATOM   2940  C CE1   . PHE A 1 378 ? -42.232 -19.429 -21.588  1.00 54.24  ? 378 PHE A CE1   1 
ATOM   2941  C CE2   . PHE A 1 378 ? -43.528 -18.950 -19.645  1.00 58.23  ? 378 PHE A CE2   1 
ATOM   2942  C CZ    . PHE A 1 378 ? -42.318 -18.914 -20.311  1.00 53.26  ? 378 PHE A CZ    1 
ATOM   2943  N N     . LEU A 1 379 ? -43.700 -23.353 -22.369  1.00 47.72  ? 379 LEU A N     1 
ATOM   2944  C CA    . LEU A 1 379 ? -42.489 -23.955 -22.890  1.00 49.99  ? 379 LEU A CA    1 
ATOM   2945  C C     . LEU A 1 379 ? -42.787 -24.989 -23.967  1.00 52.18  ? 379 LEU A C     1 
ATOM   2946  O O     . LEU A 1 379 ? -41.909 -25.244 -24.789  1.00 50.54  ? 379 LEU A O     1 
ATOM   2947  C CB    . LEU A 1 379 ? -41.674 -24.570 -21.744  1.00 49.68  ? 379 LEU A CB    1 
ATOM   2948  C CG    . LEU A 1 379 ? -40.923 -23.554 -20.879  1.00 57.40  ? 379 LEU A CG    1 
ATOM   2949  C CD1   . LEU A 1 379 ? -39.898 -24.211 -19.974  1.00 57.31  ? 379 LEU A CD1   1 
ATOM   2950  C CD2   . LEU A 1 379 ? -40.233 -22.504 -21.743  1.00 58.70  ? 379 LEU A CD2   1 
ATOM   2951  N N     . ASN A 1 380 ? -44.010 -25.547 -23.992  1.00 54.54  ? 380 ASN A N     1 
ATOM   2952  C CA    . ASN A 1 380 ? -44.318 -26.629 -24.918  1.00 58.26  ? 380 ASN A CA    1 
ATOM   2953  C C     . ASN A 1 380 ? -44.926 -26.132 -26.219  1.00 56.60  ? 380 ASN A C     1 
ATOM   2954  O O     . ASN A 1 380 ? -45.133 -26.949 -27.113  1.00 62.35  ? 380 ASN A O     1 
ATOM   2955  C CB    . ASN A 1 380 ? -45.266 -27.666 -24.325  1.00 65.84  ? 380 ASN A CB    1 
ATOM   2956  C CG    . ASN A 1 380 ? -44.583 -28.456 -23.238  1.00 65.85  ? 380 ASN A CG    1 
ATOM   2957  O OD1   . ASN A 1 380 ? -43.414 -28.825 -23.368  1.00 75.65  ? 380 ASN A OD1   1 
ATOM   2958  N ND2   . ASN A 1 380 ? -45.279 -28.647 -22.137  1.00 59.84  ? 380 ASN A ND2   1 
ATOM   2959  N N     . TRP A 1 381 ? -45.151 -24.816 -26.335  1.00 51.75  ? 381 TRP A N     1 
ATOM   2960  C CA    . TRP A 1 381 ? -45.811 -24.219 -27.497  1.00 51.93  ? 381 TRP A CA    1 
ATOM   2961  C C     . TRP A 1 381 ? -45.350 -24.798 -28.843  1.00 48.12  ? 381 TRP A C     1 
ATOM   2962  O O     . TRP A 1 381 ? -46.152 -25.031 -29.751  1.00 44.60  ? 381 TRP A O     1 
ATOM   2963  C CB    . TRP A 1 381 ? -45.594 -22.706 -27.480  1.00 46.68  ? 381 TRP A CB    1 
ATOM   2964  C CG    . TRP A 1 381 ? -46.195 -22.034 -28.667  1.00 39.87  ? 381 TRP A CG    1 
ATOM   2965  C CD1   . TRP A 1 381 ? -45.522 -21.452 -29.704  1.00 35.71  ? 381 TRP A CD1   1 
ATOM   2966  C CD2   . TRP A 1 381 ? -47.596 -21.927 -28.973  1.00 40.95  ? 381 TRP A CD2   1 
ATOM   2967  N NE1   . TRP A 1 381 ? -46.410 -20.949 -30.617  1.00 37.24  ? 381 TRP A NE1   1 
ATOM   2968  C CE2   . TRP A 1 381 ? -47.689 -21.232 -30.206  1.00 37.84  ? 381 TRP A CE2   1 
ATOM   2969  C CE3   . TRP A 1 381 ? -48.776 -22.355 -28.344  1.00 42.25  ? 381 TRP A CE3   1 
ATOM   2970  C CZ2   . TRP A 1 381 ? -48.913 -20.955 -30.808  1.00 35.24  ? 381 TRP A CZ2   1 
ATOM   2971  C CZ3   . TRP A 1 381 ? -49.997 -22.085 -28.944  1.00 40.78  ? 381 TRP A CZ3   1 
ATOM   2972  C CH2   . TRP A 1 381 ? -50.055 -21.397 -30.164  1.00 41.65  ? 381 TRP A CH2   1 
ATOM   2973  N N     . ASP A 1 382 ? -44.054 -25.050 -28.957  1.00 46.49  ? 382 ASP A N     1 
ATOM   2974  C CA    . ASP A 1 382 ? -43.443 -25.332 -30.232  1.00 53.93  ? 382 ASP A CA    1 
ATOM   2975  C C     . ASP A 1 382 ? -42.690 -26.663 -30.156  1.00 53.11  ? 382 ASP A C     1 
ATOM   2976  O O     . ASP A 1 382 ? -41.692 -26.864 -30.838  1.00 52.21  ? 382 ASP A O     1 
ATOM   2977  C CB    . ASP A 1 382 ? -42.564 -24.135 -30.600  1.00 66.69  ? 382 ASP A CB    1 
ATOM   2978  C CG    . ASP A 1 382 ? -42.073 -24.140 -32.033  1.00 74.78  ? 382 ASP A CG    1 
ATOM   2979  O OD1   . ASP A 1 382 ? -42.636 -24.897 -32.846  1.00 75.67  ? 382 ASP A OD1   1 
ATOM   2980  O OD2   . ASP A 1 382 ? -41.092 -23.421 -32.304  1.00 97.72  ? 382 ASP A OD2   1 
ATOM   2981  N N     . GLY A 1 383 ? -43.166 -27.584 -29.317  1.00 52.50  ? 383 GLY A N     1 
ATOM   2982  C CA    . GLY A 1 383 ? -42.605 -28.924 -29.290  1.00 57.56  ? 383 GLY A CA    1 
ATOM   2983  C C     . GLY A 1 383 ? -41.713 -29.188 -28.077  1.00 64.97  ? 383 GLY A C     1 
ATOM   2984  O O     . GLY A 1 383 ? -41.369 -30.338 -27.824  1.00 57.45  ? 383 GLY A O     1 
ATOM   2985  N N     . GLY A 1 384 ? -41.359 -28.130 -27.327  1.00 68.59  ? 384 GLY A N     1 
ATOM   2986  C CA    . GLY A 1 384 ? -40.575 -28.260 -26.107  1.00 70.12  ? 384 GLY A CA    1 
ATOM   2987  C C     . GLY A 1 384 ? -39.186 -27.642 -26.265  1.00 69.92  ? 384 GLY A C     1 
ATOM   2988  O O     . GLY A 1 384 ? -38.382 -28.135 -27.045  1.00 73.70  ? 384 GLY A O     1 
ATOM   2989  N N     . GLY A 1 385 ? -38.918 -26.548 -25.543  1.00 65.02  ? 385 GLY A N     1 
ATOM   2990  C CA    . GLY A 1 385 ? -37.566 -26.025 -25.457  1.00 67.77  ? 385 GLY A CA    1 
ATOM   2991  C C     . GLY A 1 385 ? -37.323 -25.201 -24.191  1.00 66.71  ? 385 GLY A C     1 
ATOM   2992  O O     . GLY A 1 385 ? -37.980 -25.415 -23.178  1.00 60.96  ? 385 GLY A O     1 
ATOM   2993  N N     . GLY A 1 386 ? -36.357 -24.269 -24.276  1.00 66.14  ? 386 GLY A N     1 
ATOM   2994  C CA    . GLY A 1 386 ? -36.078 -23.312 -23.218  1.00 62.82  ? 386 GLY A CA    1 
ATOM   2995  C C     . GLY A 1 386 ? -36.708 -21.957 -23.522  1.00 57.15  ? 386 GLY A C     1 
ATOM   2996  O O     . GLY A 1 386 ? -37.250 -21.785 -24.606  1.00 46.49  ? 386 GLY A O     1 
ATOM   2997  N N     . HIS A 1 387 ? -36.654 -21.036 -22.541  1.00 61.30  ? 387 HIS A N     1 
ATOM   2998  C CA    . HIS A 1 387 ? -37.131 -19.669 -22.703  1.00 56.16  ? 387 HIS A CA    1 
ATOM   2999  C C     . HIS A 1 387 ? -35.997 -18.685 -22.433  1.00 57.38  ? 387 HIS A C     1 
ATOM   3000  O O     . HIS A 1 387 ? -35.084 -18.994 -21.673  1.00 55.46  ? 387 HIS A O     1 
ATOM   3001  C CB    . HIS A 1 387 ? -38.353 -19.350 -21.824  1.00 48.58  ? 387 HIS A CB    1 
ATOM   3002  C CG    . HIS A 1 387 ? -38.236 -19.349 -20.315  1.00 58.54  ? 387 HIS A CG    1 
ATOM   3003  N ND1   . HIS A 1 387 ? -38.590 -18.196 -19.647  1.00 64.62  ? 387 HIS A ND1   1 
ATOM   3004  C CD2   . HIS A 1 387 ? -37.957 -20.274 -19.344  1.00 66.64  ? 387 HIS A CD2   1 
ATOM   3005  C CE1   . HIS A 1 387 ? -38.523 -18.374 -18.334  1.00 69.07  ? 387 HIS A CE1   1 
ATOM   3006  N NE2   . HIS A 1 387 ? -38.136 -19.686 -18.060  1.00 68.97  ? 387 HIS A NE2   1 
ATOM   3007  N N     . VAL A 1 388 ? -36.081 -17.516 -23.090  1.00 52.44  ? 388 VAL A N     1 
ATOM   3008  C CA    . VAL A 1 388 ? -35.380 -16.309 -22.689  1.00 52.61  ? 388 VAL A CA    1 
ATOM   3009  C C     . VAL A 1 388 ? -36.399 -15.196 -22.442  1.00 55.46  ? 388 VAL A C     1 
ATOM   3010  O O     . VAL A 1 388 ? -37.367 -15.059 -23.197  1.00 52.14  ? 388 VAL A O     1 
ATOM   3011  C CB    . VAL A 1 388 ? -34.367 -15.878 -23.758  1.00 59.93  ? 388 VAL A CB    1 
ATOM   3012  C CG1   . VAL A 1 388 ? -34.035 -14.412 -23.651  1.00 73.40  ? 388 VAL A CG1   1 
ATOM   3013  C CG2   . VAL A 1 388 ? -33.094 -16.681 -23.638  1.00 75.42  ? 388 VAL A CG2   1 
ATOM   3014  N N     . GLY A 1 389 ? -36.147 -14.388 -21.399  1.00 54.89  ? 389 GLY A N     1 
ATOM   3015  C CA    . GLY A 1 389 ? -36.950 -13.207 -21.101  1.00 57.78  ? 389 GLY A CA    1 
ATOM   3016  C C     . GLY A 1 389 ? -36.180 -11.891 -21.282  1.00 56.61  ? 389 GLY A C     1 
ATOM   3017  O O     . GLY A 1 389 ? -34.976 -11.801 -21.012  1.00 55.24  ? 389 GLY A O     1 
ATOM   3018  N N     . PHE A 1 390 ? -36.904 -10.863 -21.749  1.00 48.13  ? 390 PHE A N     1 
ATOM   3019  C CA    . PHE A 1 390 ? -36.371 -9.513  -21.828  1.00 41.96  ? 390 PHE A CA    1 
ATOM   3020  C C     . PHE A 1 390 ? -37.445 -8.545  -21.367  1.00 40.78  ? 390 PHE A C     1 
ATOM   3021  O O     . PHE A 1 390 ? -38.491 -8.442  -22.010  1.00 43.84  ? 390 PHE A O     1 
ATOM   3022  C CB    . PHE A 1 390 ? -35.897 -9.206  -23.247  1.00 43.89  ? 390 PHE A CB    1 
ATOM   3023  C CG    . PHE A 1 390 ? -35.408 -7.798  -23.440  1.00 43.15  ? 390 PHE A CG    1 
ATOM   3024  C CD1   . PHE A 1 390 ? -34.290 -7.342  -22.761  1.00 41.70  ? 390 PHE A CD1   1 
ATOM   3025  C CD2   . PHE A 1 390 ? -36.081 -6.922  -24.289  1.00 45.01  ? 390 PHE A CD2   1 
ATOM   3026  C CE1   . PHE A 1 390 ? -33.842 -6.046  -22.954  1.00 41.85  ? 390 PHE A CE1   1 
ATOM   3027  C CE2   . PHE A 1 390 ? -35.624 -5.635  -24.497  1.00 36.54  ? 390 PHE A CE2   1 
ATOM   3028  C CZ    . PHE A 1 390 ? -34.519 -5.198  -23.814  1.00 41.32  ? 390 PHE A CZ    1 
ATOM   3029  N N     . SER A 1 391 ? -37.169 -7.833  -20.265  1.00 37.45  ? 391 SER A N     1 
ATOM   3030  C CA    . SER A 1 391 ? -38.216 -7.125  -19.545  1.00 39.70  ? 391 SER A CA    1 
ATOM   3031  C C     . SER A 1 391 ? -37.825 -5.689  -19.167  1.00 36.56  ? 391 SER A C     1 
ATOM   3032  O O     . SER A 1 391 ? -37.906 -5.284  -18.007  1.00 35.71  ? 391 SER A O     1 
ATOM   3033  C CB    . SER A 1 391 ? -38.602 -7.950  -18.317  1.00 43.83  ? 391 SER A CB    1 
ATOM   3034  O OG    . SER A 1 391 ? -37.453 -8.326  -17.573  1.00 42.94  ? 391 SER A OG    1 
ATOM   3035  N N     . PRO A 1 392 ? -37.423 -4.823  -20.113  1.00 34.63  ? 392 PRO A N     1 
ATOM   3036  C CA    . PRO A 1 392 ? -36.959 -3.486  -19.759  1.00 36.64  ? 392 PRO A CA    1 
ATOM   3037  C C     . PRO A 1 392 ? -38.071 -2.612  -19.185  1.00 39.62  ? 392 PRO A C     1 
ATOM   3038  O O     . PRO A 1 392 ? -39.260 -2.926  -19.309  1.00 40.51  ? 392 PRO A O     1 
ATOM   3039  C CB    . PRO A 1 392 ? -36.462 -2.941  -21.113  1.00 35.11  ? 392 PRO A CB    1 
ATOM   3040  C CG    . PRO A 1 392 ? -37.348 -3.604  -22.076  1.00 32.75  ? 392 PRO A CG    1 
ATOM   3041  C CD    . PRO A 1 392 ? -37.400 -5.036  -21.556  1.00 35.87  ? 392 PRO A CD    1 
ATOM   3042  N N     . VAL A 1 393 ? -37.649 -1.497  -18.586  1.00 34.23  ? 393 VAL A N     1 
ATOM   3043  C CA    . VAL A 1 393 ? -38.543 -0.559  -17.944  1.00 34.51  ? 393 VAL A CA    1 
ATOM   3044  C C     . VAL A 1 393 ? -38.888 0.610   -18.871  1.00 34.58  ? 393 VAL A C     1 
ATOM   3045  O O     . VAL A 1 393 ? -38.011 1.087   -19.576  1.00 32.91  ? 393 VAL A O     1 
ATOM   3046  C CB    . VAL A 1 393 ? -37.856 -0.007  -16.697  1.00 37.61  ? 393 VAL A CB    1 
ATOM   3047  C CG1   . VAL A 1 393 ? -38.834 0.833   -15.915  1.00 42.23  ? 393 VAL A CG1   1 
ATOM   3048  C CG2   . VAL A 1 393 ? -37.300 -1.135  -15.863  1.00 47.00  ? 393 VAL A CG2   1 
ATOM   3049  N N     . SER A 1 394 ? -40.120 1.129   -18.740  1.00 30.86  ? 394 SER A N     1 
ATOM   3050  C CA    . SER A 1 394 ? -40.638 2.218   -19.542  1.00 36.13  ? 394 SER A CA    1 
ATOM   3051  C C     . SER A 1 394 ? -41.738 2.993   -18.791  1.00 35.49  ? 394 SER A C     1 
ATOM   3052  O O     . SER A 1 394 ? -42.310 2.552   -17.812  1.00 38.81  ? 394 SER A O     1 
ATOM   3053  C CB    . SER A 1 394 ? -41.130 1.681   -20.845  1.00 41.38  ? 394 SER A CB    1 
ATOM   3054  O OG    . SER A 1 394 ? -42.106 0.670   -20.634  1.00 45.19  ? 394 SER A OG    1 
ATOM   3055  N N     . PRO A 1 395 ? -41.997 4.255   -19.137  1.00 34.57  ? 395 PRO A N     1 
ATOM   3056  C CA    . PRO A 1 395 ? -43.145 4.974   -18.594  1.00 38.23  ? 395 PRO A CA    1 
ATOM   3057  C C     . PRO A 1 395 ? -44.464 4.307   -18.980  1.00 42.69  ? 395 PRO A C     1 
ATOM   3058  O O     . PRO A 1 395 ? -44.588 3.738   -20.071  1.00 44.51  ? 395 PRO A O     1 
ATOM   3059  C CB    . PRO A 1 395 ? -43.087 6.361   -19.277  1.00 37.05  ? 395 PRO A CB    1 
ATOM   3060  C CG    . PRO A 1 395 ? -41.688 6.468   -19.853  1.00 33.24  ? 395 PRO A CG    1 
ATOM   3061  C CD    . PRO A 1 395 ? -41.210 5.053   -20.083  1.00 34.93  ? 395 PRO A CD    1 
ATOM   3062  N N     . ILE A 1 396 ? -45.452 4.405   -18.090  1.00 39.76  ? 396 ILE A N     1 
ATOM   3063  C CA    . ILE A 1 396 ? -46.752 3.807   -18.346  1.00 39.24  ? 396 ILE A CA    1 
ATOM   3064  C C     . ILE A 1 396 ? -47.500 4.687   -19.342  1.00 38.83  ? 396 ILE A C     1 
ATOM   3065  O O     . ILE A 1 396 ? -48.273 5.556   -18.932  1.00 32.38  ? 396 ILE A O     1 
ATOM   3066  C CB    . ILE A 1 396 ? -47.598 3.615   -17.075  1.00 38.42  ? 396 ILE A CB    1 
ATOM   3067  C CG1   . ILE A 1 396 ? -46.907 2.776   -15.999  1.00 38.45  ? 396 ILE A CG1   1 
ATOM   3068  C CG2   . ILE A 1 396 ? -48.931 2.997   -17.448  1.00 41.00  ? 396 ILE A CG2   1 
ATOM   3069  C CD1   . ILE A 1 396 ? -47.549 2.890   -14.625  1.00 36.17  ? 396 ILE A CD1   1 
ATOM   3070  N N     . THR A 1 397 ? -47.313 4.374   -20.634  1.00 39.42  ? 397 THR A N     1 
ATOM   3071  C CA    . THR A 1 397 ? -47.841 5.163   -21.750  1.00 42.10  ? 397 THR A CA    1 
ATOM   3072  C C     . THR A 1 397 ? -48.262 4.253   -22.912  1.00 39.85  ? 397 THR A C     1 
ATOM   3073  O O     . THR A 1 397 ? -47.513 3.367   -23.312  1.00 45.87  ? 397 THR A O     1 
ATOM   3074  C CB    . THR A 1 397 ? -46.710 6.135   -22.093  1.00 40.34  ? 397 THR A CB    1 
ATOM   3075  O OG1   . THR A 1 397 ? -46.871 7.243   -21.198  1.00 45.36  ? 397 THR A OG1   1 
ATOM   3076  C CG2   . THR A 1 397 ? -46.667 6.549   -23.529  1.00 35.80  ? 397 THR A CG2   1 
ATOM   3077  N N     . GLY A 1 398 ? -49.457 4.457   -23.464  1.00 39.85  ? 398 GLY A N     1 
ATOM   3078  C CA    . GLY A 1 398 ? -49.887 3.780   -24.681  1.00 34.91  ? 398 GLY A CA    1 
ATOM   3079  C C     . GLY A 1 398 ? -48.817 3.778   -25.778  1.00 37.17  ? 398 GLY A C     1 
ATOM   3080  O O     . GLY A 1 398 ? -48.534 2.753   -26.392  1.00 43.37  ? 398 GLY A O     1 
ATOM   3081  N N     . LYS A 1 399 ? -48.234 4.951   -25.993  1.00 38.73  ? 399 LYS A N     1 
ATOM   3082  C CA    . LYS A 1 399 ? -47.200 5.235   -26.972  1.00 45.00  ? 399 LYS A CA    1 
ATOM   3083  C C     . LYS A 1 399 ? -45.951 4.381   -26.711  1.00 40.15  ? 399 LYS A C     1 
ATOM   3084  O O     . LYS A 1 399 ? -45.387 3.814   -27.630  1.00 41.42  ? 399 LYS A O     1 
ATOM   3085  C CB    . LYS A 1 399 ? -46.997 6.760   -26.942  1.00 48.43  ? 399 LYS A CB    1 
ATOM   3086  C CG    . LYS A 1 399 ? -46.226 7.374   -28.100  1.00 65.79  ? 399 LYS A CG    1 
ATOM   3087  C CD    . LYS A 1 399 ? -44.744 7.674   -27.792  1.00 83.70  ? 399 LYS A CD    1 
ATOM   3088  C CE    . LYS A 1 399 ? -44.025 8.461   -28.880  1.00 89.86  ? 399 LYS A CE    1 
ATOM   3089  N NZ    . LYS A 1 399 ? -43.862 7.702   -30.154  1.00 87.77  ? 399 LYS A NZ    1 
ATOM   3090  N N     . ASP A 1 400 ? -45.546 4.193   -25.453  1.00 44.23  ? 400 ASP A N     1 
ATOM   3091  C CA    . ASP A 1 400 ? -44.399 3.349   -25.136  1.00 42.29  ? 400 ASP A CA    1 
ATOM   3092  C C     . ASP A 1 400 ? -44.776 1.876   -25.247  1.00 41.02  ? 400 ASP A C     1 
ATOM   3093  O O     . ASP A 1 400 ? -43.958 1.062   -25.679  1.00 37.05  ? 400 ASP A O     1 
ATOM   3094  C CB    . ASP A 1 400 ? -43.863 3.621   -23.735  1.00 41.00  ? 400 ASP A CB    1 
ATOM   3095  C CG    . ASP A 1 400 ? -43.187 4.977   -23.605  1.00 41.64  ? 400 ASP A CG    1 
ATOM   3096  O OD1   . ASP A 1 400 ? -42.091 5.127   -24.134  1.00 49.95  ? 400 ASP A OD1   1 
ATOM   3097  O OD2   . ASP A 1 400 ? -43.772 5.870   -22.995  1.00 37.94  ? 400 ASP A OD2   1 
ATOM   3098  N N     . ALA A 1 401 ? -46.021 1.558   -24.861  1.00 40.39  ? 401 ALA A N     1 
ATOM   3099  C CA    . ALA A 1 401 ? -46.521 0.204   -24.940  1.00 39.11  ? 401 ALA A CA    1 
ATOM   3100  C C     . ALA A 1 401 ? -46.479 -0.259  -26.395  1.00 44.51  ? 401 ALA A C     1 
ATOM   3101  O O     . ALA A 1 401 ? -45.855 -1.272  -26.694  1.00 47.38  ? 401 ALA A O     1 
ATOM   3102  C CB    . ALA A 1 401 ? -47.904 0.130   -24.364  1.00 40.18  ? 401 ALA A CB    1 
ATOM   3103  N N     . ILE A 1 402 ? -47.101 0.497   -27.302  1.00 42.68  ? 402 ILE A N     1 
ATOM   3104  C CA    . ILE A 1 402 ? -47.255 0.043   -28.671  1.00 43.49  ? 402 ILE A CA    1 
ATOM   3105  C C     . ILE A 1 402 ? -45.942 0.124   -29.446  1.00 42.82  ? 402 ILE A C     1 
ATOM   3106  O O     . ILE A 1 402 ? -45.687 -0.731  -30.297  1.00 41.07  ? 402 ILE A O     1 
ATOM   3107  C CB    . ILE A 1 402 ? -48.410 0.768   -29.388  1.00 49.20  ? 402 ILE A CB    1 
ATOM   3108  C CG1   . ILE A 1 402 ? -48.846 -0.023  -30.621  1.00 51.79  ? 402 ILE A CG1   1 
ATOM   3109  C CG2   . ILE A 1 402 ? -48.064 2.203   -29.733  1.00 47.95  ? 402 ILE A CG2   1 
ATOM   3110  C CD1   . ILE A 1 402 ? -50.331 -0.160  -30.747  1.00 52.94  ? 402 ILE A CD1   1 
ATOM   3111  N N     . LYS A 1 403 ? -45.094 1.117   -29.150  1.00 40.25  ? 403 LYS A N     1 
ATOM   3112  C CA    . LYS A 1 403 ? -43.793 1.151   -29.793  1.00 45.80  ? 403 LYS A CA    1 
ATOM   3113  C C     . LYS A 1 403 ? -43.034 -0.146  -29.494  1.00 41.87  ? 403 LYS A C     1 
ATOM   3114  O O     . LYS A 1 403 ? -42.437 -0.754  -30.379  1.00 37.91  ? 403 LYS A O     1 
ATOM   3115  C CB    . LYS A 1 403 ? -42.953 2.358   -29.353  1.00 49.55  ? 403 LYS A CB    1 
ATOM   3116  C CG    . LYS A 1 403 ? -41.787 2.696   -30.278  1.00 47.60  ? 403 LYS A CG    1 
ATOM   3117  C CD    . LYS A 1 403 ? -40.668 3.345   -29.549  1.00 60.69  ? 403 LYS A CD    1 
ATOM   3118  C CE    . LYS A 1 403 ? -41.006 4.738   -29.045  1.00 67.06  ? 403 LYS A CE    1 
ATOM   3119  N NZ    . LYS A 1 403 ? -40.016 5.211   -28.042  1.00 60.80  ? 403 LYS A NZ    1 
ATOM   3120  N N     . GLN A 1 404 ? -43.063 -0.571  -28.233  1.00 37.17  ? 404 GLN A N     1 
ATOM   3121  C CA    . GLN A 1 404 ? -42.328 -1.752  -27.841  1.00 38.94  ? 404 GLN A CA    1 
ATOM   3122  C C     . GLN A 1 404 ? -42.921 -2.990  -28.496  1.00 38.45  ? 404 GLN A C     1 
ATOM   3123  O O     . GLN A 1 404 ? -42.159 -3.839  -28.949  1.00 42.29  ? 404 GLN A O     1 
ATOM   3124  C CB    . GLN A 1 404 ? -42.261 -1.852  -26.320  1.00 39.90  ? 404 GLN A CB    1 
ATOM   3125  C CG    . GLN A 1 404 ? -41.319 -0.811  -25.752  1.00 39.21  ? 404 GLN A CG    1 
ATOM   3126  C CD    . GLN A 1 404 ? -41.331 -0.854  -24.250  1.00 42.03  ? 404 GLN A CD    1 
ATOM   3127  O OE1   . GLN A 1 404 ? -40.436 -1.433  -23.641  1.00 37.96  ? 404 GLN A OE1   1 
ATOM   3128  N NE2   . GLN A 1 404 ? -42.376 -0.287  -23.659  1.00 37.97  ? 404 GLN A NE2   1 
ATOM   3129  N N     . TYR A 1 405 ? -44.256 -3.095  -28.492  1.00 34.45  ? 405 TYR A N     1 
ATOM   3130  C CA    . TYR A 1 405 ? -44.947 -4.173  -29.162  1.00 35.39  ? 405 TYR A CA    1 
ATOM   3131  C C     . TYR A 1 405 ? -44.506 -4.263  -30.641  1.00 41.41  ? 405 TYR A C     1 
ATOM   3132  O O     . TYR A 1 405 ? -44.047 -5.310  -31.090  1.00 40.72  ? 405 TYR A O     1 
ATOM   3133  C CB    . TYR A 1 405 ? -46.459 -3.989  -29.018  1.00 37.82  ? 405 TYR A CB    1 
ATOM   3134  C CG    . TYR A 1 405 ? -47.260 -4.904  -29.905  1.00 43.28  ? 405 TYR A CG    1 
ATOM   3135  C CD1   . TYR A 1 405 ? -47.288 -6.269  -29.660  1.00 50.53  ? 405 TYR A CD1   1 
ATOM   3136  C CD2   . TYR A 1 405 ? -47.854 -4.440  -31.067  1.00 55.15  ? 405 TYR A CD2   1 
ATOM   3137  C CE1   . TYR A 1 405 ? -47.943 -7.144  -30.512  1.00 51.60  ? 405 TYR A CE1   1 
ATOM   3138  C CE2   . TYR A 1 405 ? -48.547 -5.297  -31.913  1.00 62.10  ? 405 TYR A CE2   1 
ATOM   3139  C CZ    . TYR A 1 405 ? -48.577 -6.654  -31.637  1.00 52.30  ? 405 TYR A CZ    1 
ATOM   3140  O OH    . TYR A 1 405 ? -49.234 -7.523  -32.431  1.00 51.13  ? 405 TYR A OH    1 
ATOM   3141  N N     . ASN A 1 406 ? -44.595 -3.169  -31.404  1.00 38.93  ? 406 ASN A N     1 
ATOM   3142  C CA    . ASN A 1 406 ? -44.274 -3.216  -32.823  1.00 38.44  ? 406 ASN A CA    1 
ATOM   3143  C C     . ASN A 1 406 ? -42.820 -3.576  -33.049  1.00 41.62  ? 406 ASN A C     1 
ATOM   3144  O O     . ASN A 1 406 ? -42.526 -4.404  -33.926  1.00 45.10  ? 406 ASN A O     1 
ATOM   3145  C CB    . ASN A 1 406 ? -44.494 -1.893  -33.545  1.00 37.24  ? 406 ASN A CB    1 
ATOM   3146  C CG    . ASN A 1 406 ? -45.950 -1.522  -33.567  1.00 40.56  ? 406 ASN A CG    1 
ATOM   3147  O OD1   . ASN A 1 406 ? -46.812 -2.389  -33.636  1.00 50.43  ? 406 ASN A OD1   1 
ATOM   3148  N ND2   . ASN A 1 406 ? -46.230 -0.248  -33.421  1.00 49.15  ? 406 ASN A ND2   1 
ATOM   3149  N N     . MET A 1 407 ? -41.936 -2.938  -32.268  1.00 39.61  ? 407 MET A N     1 
ATOM   3150  C CA    . MET A 1 407 ? -40.499 -3.142  -32.405  1.00 44.57  ? 407 MET A CA    1 
ATOM   3151  C C     . MET A 1 407 ? -40.173 -4.620  -32.251  1.00 41.45  ? 407 MET A C     1 
ATOM   3152  O O     . MET A 1 407 ? -39.452 -5.160  -33.067  1.00 50.91  ? 407 MET A O     1 
ATOM   3153  C CB    . MET A 1 407 ? -39.709 -2.417  -31.315  1.00 48.62  ? 407 MET A CB    1 
ATOM   3154  C CG    . MET A 1 407 ? -39.531 -0.962  -31.536  1.00 52.17  ? 407 MET A CG    1 
ATOM   3155  S SD    . MET A 1 407 ? -38.828 -0.261  -30.027  1.00 52.84  ? 407 MET A SD    1 
ATOM   3156  C CE    . MET A 1 407 ? -37.091 -0.675  -30.209  1.00 44.68  ? 407 MET A CE    1 
ATOM   3157  N N     . VAL A 1 408 ? -40.681 -5.230  -31.174  1.00 40.94  ? 408 VAL A N     1 
ATOM   3158  C CA    . VAL A 1 408 ? -40.281 -6.562  -30.762  1.00 45.58  ? 408 VAL A CA    1 
ATOM   3159  C C     . VAL A 1 408 ? -40.989 -7.595  -31.631  1.00 47.01  ? 408 VAL A C     1 
ATOM   3160  O O     . VAL A 1 408 ? -40.319 -8.462  -32.198  1.00 48.23  ? 408 VAL A O     1 
ATOM   3161  C CB    . VAL A 1 408 ? -40.578 -6.828  -29.274  1.00 48.04  ? 408 VAL A CB    1 
ATOM   3162  C CG1   . VAL A 1 408 ? -40.335 -8.287  -28.901  1.00 50.13  ? 408 VAL A CG1   1 
ATOM   3163  C CG2   . VAL A 1 408 ? -39.770 -5.927  -28.367  1.00 46.54  ? 408 VAL A CG2   1 
ATOM   3164  N N     . SER A 1 409 ? -42.330 -7.509  -31.722  1.00 43.25  ? 409 SER A N     1 
ATOM   3165  C CA    . SER A 1 409 ? -43.084 -8.488  -32.494  1.00 44.49  ? 409 SER A CA    1 
ATOM   3166  C C     . SER A 1 409 ? -42.494 -8.656  -33.907  1.00 47.74  ? 409 SER A C     1 
ATOM   3167  O O     . SER A 1 409 ? -42.233 -9.782  -34.316  1.00 52.10  ? 409 SER A O     1 
ATOM   3168  C CB    . SER A 1 409 ? -44.553 -8.208  -32.506  1.00 44.59  ? 409 SER A CB    1 
ATOM   3169  O OG    . SER A 1 409 ? -44.848 -6.983  -33.166  1.00 47.17  ? 409 SER A OG    1 
ATOM   3170  N N     . SER A 1 410 ? -42.189 -7.577  -34.634  1.00 42.09  ? 410 SER A N     1 
ATOM   3171  C CA    . SER A 1 410 ? -41.659 -7.723  -35.988  1.00 48.34  ? 410 SER A CA    1 
ATOM   3172  C C     . SER A 1 410 ? -40.377 -8.559  -36.018  1.00 47.40  ? 410 SER A C     1 
ATOM   3173  O O     . SER A 1 410 ? -40.212 -9.427  -36.865  1.00 58.45  ? 410 SER A O     1 
ATOM   3174  C CB    . SER A 1 410 ? -41.390 -6.397  -36.620  1.00 49.60  ? 410 SER A CB    1 
ATOM   3175  O OG    . SER A 1 410 ? -42.520 -5.585  -36.463  1.00 57.21  ? 410 SER A OG    1 
ATOM   3176  N N     . ARG A 1 411 ? -39.435 -8.264  -35.138  1.00 38.55  ? 411 ARG A N     1 
ATOM   3177  C CA    . ARG A 1 411 ? -38.144 -8.922  -35.199  1.00 43.53  ? 411 ARG A CA    1 
ATOM   3178  C C     . ARG A 1 411 ? -38.283 -10.359 -34.710  1.00 38.76  ? 411 ARG A C     1 
ATOM   3179  O O     . ARG A 1 411 ? -37.767 -11.275 -35.309  1.00 42.89  ? 411 ARG A O     1 
ATOM   3180  C CB    . ARG A 1 411 ? -37.081 -8.142  -34.399  1.00 45.62  ? 411 ARG A CB    1 
ATOM   3181  C CG    . ARG A 1 411 ? -36.702 -6.832  -35.076  1.00 50.26  ? 411 ARG A CG    1 
ATOM   3182  C CD    . ARG A 1 411 ? -35.455 -6.219  -34.499  1.00 57.05  ? 411 ARG A CD    1 
ATOM   3183  N NE    . ARG A 1 411 ? -34.854 -5.181  -35.323  1.00 51.55  ? 411 ARG A NE    1 
ATOM   3184  C CZ    . ARG A 1 411 ? -34.098 -5.399  -36.390  1.00 46.76  ? 411 ARG A CZ    1 
ATOM   3185  N NH1   . ARG A 1 411 ? -34.245 -6.481  -37.125  1.00 39.61  ? 411 ARG A NH1   1 
ATOM   3186  N NH2   . ARG A 1 411 ? -33.228 -4.481  -36.757  1.00 57.09  ? 411 ARG A NH2   1 
ATOM   3187  N N     . VAL A 1 412 ? -38.961 -10.561 -33.597  1.00 38.79  ? 412 VAL A N     1 
ATOM   3188  C CA    . VAL A 1 412 ? -39.177 -11.912 -33.136  1.00 42.33  ? 412 VAL A CA    1 
ATOM   3189  C C     . VAL A 1 412 ? -39.758 -12.769 -34.266  1.00 42.03  ? 412 VAL A C     1 
ATOM   3190  O O     . VAL A 1 412 ? -39.293 -13.886 -34.488  1.00 41.58  ? 412 VAL A O     1 
ATOM   3191  C CB    . VAL A 1 412 ? -40.036 -11.900 -31.866  1.00 38.68  ? 412 VAL A CB    1 
ATOM   3192  C CG1   . VAL A 1 412 ? -40.567 -13.266 -31.545  1.00 38.44  ? 412 VAL A CG1   1 
ATOM   3193  C CG2   . VAL A 1 412 ? -39.232 -11.365 -30.696  1.00 37.40  ? 412 VAL A CG2   1 
ATOM   3194  N N     . ARG A 1 413 ? -40.720 -12.223 -35.012  1.00 40.59  ? 413 ARG A N     1 
ATOM   3195  C CA    . ARG A 1 413 ? -41.429 -12.976 -36.034  1.00 42.10  ? 413 ARG A CA    1 
ATOM   3196  C C     . ARG A 1 413 ? -40.608 -13.108 -37.324  1.00 44.64  ? 413 ARG A C     1 
ATOM   3197  O O     . ARG A 1 413 ? -40.787 -14.086 -38.039  1.00 51.90  ? 413 ARG A O     1 
ATOM   3198  C CB    . ARG A 1 413 ? -42.825 -12.373 -36.265  1.00 42.31  ? 413 ARG A CB    1 
ATOM   3199  C CG    . ARG A 1 413 ? -43.861 -12.747 -35.208  1.00 43.29  ? 413 ARG A CG    1 
ATOM   3200  C CD    . ARG A 1 413 ? -45.135 -11.900 -35.230  1.00 47.51  ? 413 ARG A CD    1 
ATOM   3201  N NE    . ARG A 1 413 ? -45.979 -12.084 -36.401  1.00 52.01  ? 413 ARG A NE    1 
ATOM   3202  C CZ    . ARG A 1 413 ? -46.619 -13.213 -36.746  1.00 57.70  ? 413 ARG A CZ    1 
ATOM   3203  N NH1   . ARG A 1 413 ? -46.822 -14.191 -35.871  1.00 57.06  ? 413 ARG A NH1   1 
ATOM   3204  N NH2   . ARG A 1 413 ? -47.069 -13.353 -37.984  1.00 46.69  ? 413 ARG A NH2   1 
ATOM   3205  N N     . GLU A 1 414 ? -39.691 -12.179 -37.625  1.00 47.17  ? 414 GLU A N     1 
ATOM   3206  C CA    . GLU A 1 414 ? -38.847 -12.291 -38.807  1.00 48.38  ? 414 GLU A CA    1 
ATOM   3207  C C     . GLU A 1 414 ? -37.859 -13.432 -38.595  1.00 47.88  ? 414 GLU A C     1 
ATOM   3208  O O     . GLU A 1 414 ? -37.443 -14.127 -39.534  1.00 48.10  ? 414 GLU A O     1 
ATOM   3209  C CB    . GLU A 1 414 ? -38.102 -10.982 -39.086  1.00 54.18  ? 414 GLU A CB    1 
ATOM   3210  C CG    . GLU A 1 414 ? -37.332 -10.977 -40.417  1.00 60.44  ? 414 GLU A CG    1 
ATOM   3211  C CD    . GLU A 1 414 ? -36.617 -9.674  -40.776  1.00 64.79  ? 414 GLU A CD    1 
ATOM   3212  O OE1   . GLU A 1 414 ? -37.322 -8.702  -41.123  1.00 72.11  ? 414 GLU A OE1   1 
ATOM   3213  O OE2   . GLU A 1 414 ? -35.353 -9.613  -40.680  1.00 55.72  ? 414 GLU A OE2   1 
ATOM   3214  N N     . TYR A 1 415 ? -37.501 -13.613 -37.327  1.00 42.61  ? 415 TYR A N     1 
ATOM   3215  C CA    . TYR A 1 415 ? -36.584 -14.658 -36.920  1.00 43.69  ? 415 TYR A CA    1 
ATOM   3216  C C     . TYR A 1 415 ? -37.298 -16.008 -36.847  1.00 45.93  ? 415 TYR A C     1 
ATOM   3217  O O     . TYR A 1 415 ? -36.671 -17.017 -36.516  1.00 51.79  ? 415 TYR A O     1 
ATOM   3218  C CB    . TYR A 1 415 ? -35.934 -14.267 -35.585  1.00 45.00  ? 415 TYR A CB    1 
ATOM   3219  C CG    . TYR A 1 415 ? -34.753 -13.336 -35.735  1.00 44.27  ? 415 TYR A CG    1 
ATOM   3220  C CD1   . TYR A 1 415 ? -34.931 -12.023 -36.149  1.00 40.96  ? 415 TYR A CD1   1 
ATOM   3221  C CD2   . TYR A 1 415 ? -33.454 -13.778 -35.514  1.00 42.23  ? 415 TYR A CD2   1 
ATOM   3222  C CE1   . TYR A 1 415 ? -33.859 -11.169 -36.335  1.00 43.58  ? 415 TYR A CE1   1 
ATOM   3223  C CE2   . TYR A 1 415 ? -32.377 -12.917 -35.675  1.00 50.83  ? 415 TYR A CE2   1 
ATOM   3224  C CZ    . TYR A 1 415 ? -32.570 -11.610 -36.103  1.00 44.76  ? 415 TYR A CZ    1 
ATOM   3225  O OH    . TYR A 1 415 ? -31.494 -10.749 -36.311  1.00 40.98  ? 415 TYR A OH    1 
ATOM   3226  N N     . GLY A 1 416 ? -38.615 -16.022 -37.095  1.00 43.85  ? 416 GLY A N     1 
ATOM   3227  C CA    . GLY A 1 416 ? -39.380 -17.260 -37.156  1.00 46.71  ? 416 GLY A CA    1 
ATOM   3228  C C     . GLY A 1 416 ? -39.969 -17.730 -35.814  1.00 44.37  ? 416 GLY A C     1 
ATOM   3229  O O     . GLY A 1 416 ? -40.711 -18.707 -35.771  1.00 49.18  ? 416 GLY A O     1 
ATOM   3230  N N     . PHE A 1 417 ? -39.652 -17.048 -34.715  1.00 41.04  ? 417 PHE A N     1 
ATOM   3231  C CA    . PHE A 1 417 ? -40.317 -17.297 -33.446  1.00 39.43  ? 417 PHE A CA    1 
ATOM   3232  C C     . PHE A 1 417 ? -41.689 -16.634 -33.391  1.00 39.33  ? 417 PHE A C     1 
ATOM   3233  O O     . PHE A 1 417 ? -41.935 -15.663 -34.089  1.00 50.27  ? 417 PHE A O     1 
ATOM   3234  C CB    . PHE A 1 417 ? -39.485 -16.715 -32.323  1.00 38.41  ? 417 PHE A CB    1 
ATOM   3235  C CG    . PHE A 1 417 ? -38.093 -17.255 -32.259  1.00 40.71  ? 417 PHE A CG    1 
ATOM   3236  C CD1   . PHE A 1 417 ? -37.861 -18.508 -31.741  1.00 43.30  ? 417 PHE A CD1   1 
ATOM   3237  C CD2   . PHE A 1 417 ? -37.027 -16.514 -32.737  1.00 41.34  ? 417 PHE A CD2   1 
ATOM   3238  C CE1   . PHE A 1 417 ? -36.571 -18.987 -31.640  1.00 44.98  ? 417 PHE A CE1   1 
ATOM   3239  C CE2   . PHE A 1 417 ? -35.745 -17.010 -32.670  1.00 42.19  ? 417 PHE A CE2   1 
ATOM   3240  C CZ    . PHE A 1 417 ? -35.522 -18.248 -32.117  1.00 44.33  ? 417 PHE A CZ    1 
ATOM   3241  N N     . ASP A 1 418 ? -42.574 -17.140 -32.532  1.00 45.12  ? 418 ASP A N     1 
ATOM   3242  C CA    . ASP A 1 418 ? -43.861 -16.491 -32.283  1.00 50.32  ? 418 ASP A CA    1 
ATOM   3243  C C     . ASP A 1 418 ? -43.644 -15.407 -31.222  1.00 47.72  ? 418 ASP A C     1 
ATOM   3244  O O     . ASP A 1 418 ? -42.900 -15.613 -30.250  1.00 39.14  ? 418 ASP A O     1 
ATOM   3245  C CB    . ASP A 1 418 ? -44.958 -17.473 -31.822  1.00 49.26  ? 418 ASP A CB    1 
ATOM   3246  C CG    . ASP A 1 418 ? -45.801 -18.141 -32.900  1.00 43.58  ? 418 ASP A CG    1 
ATOM   3247  O OD1   . ASP A 1 418 ? -46.710 -17.470 -33.433  1.00 38.09  ? 418 ASP A OD1   1 
ATOM   3248  O OD2   . ASP A 1 418 ? -45.575 -19.354 -33.147  1.00 40.31  ? 418 ASP A OD2   1 
ATOM   3249  N N     . TYR A 1 419 ? -44.318 -14.271 -31.441  1.00 46.46  ? 419 TYR A N     1 
ATOM   3250  C CA    . TYR A 1 419 ? -44.365 -13.185 -30.481  1.00 41.67  ? 419 TYR A CA    1 
ATOM   3251  C C     . TYR A 1 419 ? -45.140 -13.641 -29.253  1.00 38.92  ? 419 TYR A C     1 
ATOM   3252  O O     . TYR A 1 419 ? -46.340 -13.911 -29.351  1.00 34.85  ? 419 TYR A O     1 
ATOM   3253  C CB    . TYR A 1 419 ? -45.045 -11.927 -31.043  1.00 38.49  ? 419 TYR A CB    1 
ATOM   3254  C CG    . TYR A 1 419 ? -45.241 -10.849 -30.000  1.00 37.28  ? 419 TYR A CG    1 
ATOM   3255  C CD1   . TYR A 1 419 ? -44.155 -10.204 -29.416  1.00 39.72  ? 419 TYR A CD1   1 
ATOM   3256  C CD2   . TYR A 1 419 ? -46.494 -10.561 -29.511  1.00 34.06  ? 419 TYR A CD2   1 
ATOM   3257  C CE1   . TYR A 1 419 ? -44.310 -9.258  -28.421  1.00 38.24  ? 419 TYR A CE1   1 
ATOM   3258  C CE2   . TYR A 1 419 ? -46.670 -9.640  -28.495  1.00 40.38  ? 419 TYR A CE2   1 
ATOM   3259  C CZ    . TYR A 1 419 ? -45.580 -8.982  -27.953  1.00 41.74  ? 419 TYR A CZ    1 
ATOM   3260  O OH    . TYR A 1 419 ? -45.805 -8.064  -26.967  1.00 40.29  ? 419 TYR A OH    1 
ATOM   3261  N N     . MET A 1 420 ? -44.444 -13.704 -28.108  1.00 38.01  ? 420 MET A N     1 
ATOM   3262  C CA    . MET A 1 420 ? -45.100 -13.907 -26.820  1.00 41.84  ? 420 MET A CA    1 
ATOM   3263  C C     . MET A 1 420 ? -44.687 -12.772 -25.887  1.00 42.18  ? 420 MET A C     1 
ATOM   3264  O O     . MET A 1 420 ? -43.528 -12.616 -25.496  1.00 47.07  ? 420 MET A O     1 
ATOM   3265  C CB    . MET A 1 420 ? -44.693 -15.226 -26.159  1.00 46.12  ? 420 MET A CB    1 
ATOM   3266  C CG    . MET A 1 420 ? -45.233 -16.495 -26.811  1.00 47.84  ? 420 MET A CG    1 
ATOM   3267  S SD    . MET A 1 420 ? -44.348 -17.908 -26.101  1.00 49.99  ? 420 MET A SD    1 
ATOM   3268  C CE    . MET A 1 420 ? -44.839 -19.202 -27.231  1.00 55.23  ? 420 MET A CE    1 
ATOM   3269  N N     . GLY A 1 421 ? -45.642 -11.938 -25.553  1.00 38.89  ? 421 GLY A N     1 
ATOM   3270  C CA    . GLY A 1 421 ? -45.302 -10.771 -24.790  1.00 41.23  ? 421 GLY A CA    1 
ATOM   3271  C C     . GLY A 1 421 ? -46.360 -10.459 -23.756  1.00 43.21  ? 421 GLY A C     1 
ATOM   3272  O O     . GLY A 1 421 ? -47.479 -10.960 -23.803  1.00 48.38  ? 421 GLY A O     1 
ATOM   3273  N N     . LEU A 1 422 ? -45.990 -9.524  -22.904  1.00 42.77  ? 422 LEU A N     1 
ATOM   3274  C CA    . LEU A 1 422 ? -46.737 -9.218  -21.709  1.00 44.83  ? 422 LEU A CA    1 
ATOM   3275  C C     . LEU A 1 422 ? -46.451 -7.738  -21.396  1.00 46.35  ? 422 LEU A C     1 
ATOM   3276  O O     . LEU A 1 422 ? -45.312 -7.257  -21.492  1.00 38.81  ? 422 LEU A O     1 
ATOM   3277  C CB    . LEU A 1 422 ? -46.172 -10.248 -20.732  1.00 49.46  ? 422 LEU A CB    1 
ATOM   3278  C CG    . LEU A 1 422 ? -46.634 -10.238 -19.291  1.00 51.42  ? 422 LEU A CG    1 
ATOM   3279  C CD1   . LEU A 1 422 ? -45.915 -11.334 -18.534  1.00 50.91  ? 422 LEU A CD1   1 
ATOM   3280  C CD2   . LEU A 1 422 ? -46.354 -8.888  -18.665  1.00 52.92  ? 422 LEU A CD2   1 
ATOM   3281  N N     . LEU A 1 423 ? -47.501 -6.956  -21.130  1.00 43.52  ? 423 LEU A N     1 
ATOM   3282  C CA    . LEU A 1 423 ? -47.284 -5.654  -20.530  1.00 44.05  ? 423 LEU A CA    1 
ATOM   3283  C C     . LEU A 1 423 ? -47.601 -5.679  -19.038  1.00 42.58  ? 423 LEU A C     1 
ATOM   3284  O O     . LEU A 1 423 ? -48.746 -5.842  -18.644  1.00 46.03  ? 423 LEU A O     1 
ATOM   3285  C CB    . LEU A 1 423 ? -48.059 -4.624  -21.342  1.00 45.80  ? 423 LEU A CB    1 
ATOM   3286  C CG    . LEU A 1 423 ? -47.295 -4.305  -22.629  1.00 55.19  ? 423 LEU A CG    1 
ATOM   3287  C CD1   . LEU A 1 423 ? -47.978 -4.947  -23.822  1.00 62.19  ? 423 LEU A CD1   1 
ATOM   3288  C CD2   . LEU A 1 423 ? -47.076 -2.815  -22.822  1.00 57.03  ? 423 LEU A CD2   1 
ATOM   3289  N N     . ALA A 1 424 ? -46.555 -5.595  -18.213  1.00 42.67  ? 424 ALA A N     1 
ATOM   3290  C CA    . ALA A 1 424 ? -46.714 -5.629  -16.757  1.00 48.98  ? 424 ALA A CA    1 
ATOM   3291  C C     . ALA A 1 424 ? -46.514 -4.232  -16.157  1.00 44.82  ? 424 ALA A C     1 
ATOM   3292  O O     . ALA A 1 424 ? -45.697 -3.457  -16.636  1.00 44.46  ? 424 ALA A O     1 
ATOM   3293  C CB    . ALA A 1 424 ? -45.754 -6.602  -16.118  1.00 41.31  ? 424 ALA A CB    1 
ATOM   3294  N N     . ILE A 1 425 ? -47.260 -3.936  -15.095  1.00 41.48  ? 425 ILE A N     1 
ATOM   3295  C CA    . ILE A 1 425 ? -47.047 -2.718  -14.338  1.00 42.77  ? 425 ILE A CA    1 
ATOM   3296  C C     . ILE A 1 425 ? -46.900 -3.049  -12.865  1.00 39.85  ? 425 ILE A C     1 
ATOM   3297  O O     . ILE A 1 425 ? -47.778 -3.660  -12.290  1.00 45.59  ? 425 ILE A O     1 
ATOM   3298  C CB    . ILE A 1 425 ? -48.199 -1.722  -14.537  1.00 43.32  ? 425 ILE A CB    1 
ATOM   3299  C CG1   . ILE A 1 425 ? -48.555 -1.537  -16.014  1.00 43.45  ? 425 ILE A CG1   1 
ATOM   3300  C CG2   . ILE A 1 425 ? -47.815 -0.422  -13.865  1.00 45.62  ? 425 ILE A CG2   1 
ATOM   3301  C CD1   . ILE A 1 425 ? -49.708 -0.603  -16.225  1.00 44.69  ? 425 ILE A CD1   1 
ATOM   3302  N N     . GLY A 1 426 ? -45.817 -2.579  -12.257  1.00 41.13  ? 426 GLY A N     1 
ATOM   3303  C CA    . GLY A 1 426 ? -45.602 -2.760  -10.837  1.00 45.21  ? 426 GLY A CA    1 
ATOM   3304  C C     . GLY A 1 426 ? -46.409 -1.749  -10.034  1.00 49.05  ? 426 GLY A C     1 
ATOM   3305  O O     . GLY A 1 426 ? -47.389 -2.128  -9.400   1.00 48.39  ? 426 GLY A O     1 
ATOM   3306  N N     . TRP A 1 427 ? -45.995 -0.476  -10.115  1.00 43.66  ? 427 TRP A N     1 
ATOM   3307  C CA    . TRP A 1 427 ? -46.692 0.631   -9.472   1.00 45.62  ? 427 TRP A CA    1 
ATOM   3308  C C     . TRP A 1 427 ? -46.632 1.875   -10.365  1.00 39.14  ? 427 TRP A C     1 
ATOM   3309  O O     . TRP A 1 427 ? -47.642 2.291   -10.899  1.00 44.19  ? 427 TRP A O     1 
ATOM   3310  C CB    . TRP A 1 427 ? -46.158 0.876   -8.041   1.00 43.02  ? 427 TRP A CB    1 
ATOM   3311  C CG    . TRP A 1 427 ? -46.989 1.829   -7.240   1.00 44.52  ? 427 TRP A CG    1 
ATOM   3312  C CD1   . TRP A 1 427 ? -48.151 2.437   -7.629   1.00 48.66  ? 427 TRP A CD1   1 
ATOM   3313  C CD2   . TRP A 1 427 ? -46.711 2.333   -5.925   1.00 46.21  ? 427 TRP A CD2   1 
ATOM   3314  N NE1   . TRP A 1 427 ? -48.640 3.232   -6.627   1.00 47.17  ? 427 TRP A NE1   1 
ATOM   3315  C CE2   . TRP A 1 427 ? -47.763 3.212   -5.581   1.00 45.21  ? 427 TRP A CE2   1 
ATOM   3316  C CE3   . TRP A 1 427 ? -45.676 2.148   -5.005   1.00 44.83  ? 427 TRP A CE3   1 
ATOM   3317  C CZ2   . TRP A 1 427 ? -47.803 3.890   -4.364   1.00 44.93  ? 427 TRP A CZ2   1 
ATOM   3318  C CZ3   . TRP A 1 427 ? -45.717 2.831   -3.809   1.00 43.27  ? 427 TRP A CZ3   1 
ATOM   3319  C CH2   . TRP A 1 427 ? -46.761 3.694   -3.493   1.00 41.75  ? 427 TRP A CH2   1 
ATOM   3320  N N     . ARG A 1 428 ? -45.450 2.433   -10.614  1.00 37.89  ? 428 ARG A N     1 
ATOM   3321  C CA    . ARG A 1 428 ? -45.329 3.510   -11.596  1.00 40.75  ? 428 ARG A CA    1 
ATOM   3322  C C     . ARG A 1 428 ? -44.550 3.065   -12.845  1.00 39.31  ? 428 ARG A C     1 
ATOM   3323  O O     . ARG A 1 428 ? -44.311 3.869   -13.751  1.00 35.15  ? 428 ARG A O     1 
ATOM   3324  C CB    . ARG A 1 428 ? -44.661 4.705   -10.900  1.00 40.23  ? 428 ARG A CB    1 
ATOM   3325  C CG    . ARG A 1 428 ? -45.490 5.333   -9.785   1.00 37.87  ? 428 ARG A CG    1 
ATOM   3326  C CD    . ARG A 1 428 ? -44.795 6.503   -9.113   1.00 40.22  ? 428 ARG A CD    1 
ATOM   3327  N NE    . ARG A 1 428 ? -45.724 7.352   -8.388   1.00 37.50  ? 428 ARG A NE    1 
ATOM   3328  C CZ    . ARG A 1 428 ? -46.250 7.059   -7.212   1.00 43.37  ? 428 ARG A CZ    1 
ATOM   3329  N NH1   . ARG A 1 428 ? -46.035 5.885   -6.636   1.00 42.04  ? 428 ARG A NH1   1 
ATOM   3330  N NH2   . ARG A 1 428 ? -46.992 7.966   -6.601   1.00 50.86  ? 428 ARG A NH2   1 
ATOM   3331  N N     . ASP A 1 429 ? -44.193 1.769   -12.911  1.00 36.35  ? 429 ASP A N     1 
ATOM   3332  C CA    . ASP A 1 429 ? -43.255 1.242   -13.887  1.00 37.46  ? 429 ASP A CA    1 
ATOM   3333  C C     . ASP A 1 429 ? -43.970 0.276   -14.846  1.00 41.00  ? 429 ASP A C     1 
ATOM   3334  O O     . ASP A 1 429 ? -44.612 -0.684  -14.408  1.00 37.31  ? 429 ASP A O     1 
ATOM   3335  C CB    . ASP A 1 429 ? -42.085 0.573   -13.157  1.00 39.25  ? 429 ASP A CB    1 
ATOM   3336  C CG    . ASP A 1 429 ? -42.491 -0.541  -12.202  1.00 42.63  ? 429 ASP A CG    1 
ATOM   3337  O OD1   . ASP A 1 429 ? -43.483 -0.347  -11.457  1.00 42.89  ? 429 ASP A OD1   1 
ATOM   3338  O OD2   . ASP A 1 429 ? -41.855 -1.614  -12.239  1.00 41.96  ? 429 ASP A OD2   1 
ATOM   3339  N N     . LEU A 1 430 ? -43.851 0.518   -16.165  1.00 40.12  ? 430 LEU A N     1 
ATOM   3340  C CA    . LEU A 1 430 ? -44.320 -0.436  -17.162  1.00 35.25  ? 430 LEU A CA    1 
ATOM   3341  C C     . LEU A 1 430 ? -43.141 -1.288  -17.590  1.00 35.58  ? 430 LEU A C     1 
ATOM   3342  O O     . LEU A 1 430 ? -42.056 -0.768  -17.794  1.00 33.63  ? 430 LEU A O     1 
ATOM   3343  C CB    . LEU A 1 430 ? -44.910 0.293   -18.368  1.00 39.77  ? 430 LEU A CB    1 
ATOM   3344  C CG    . LEU A 1 430 ? -45.453 -0.600  -19.487  1.00 43.76  ? 430 LEU A CG    1 
ATOM   3345  C CD1   . LEU A 1 430 ? -46.838 -1.122  -19.147  1.00 46.98  ? 430 LEU A CD1   1 
ATOM   3346  C CD2   . LEU A 1 430 ? -45.532 0.158   -20.795  1.00 45.25  ? 430 LEU A CD2   1 
ATOM   3347  N N     . HIS A 1 431 ? -43.364 -2.601  -17.700  1.00 37.22  ? 431 HIS A N     1 
ATOM   3348  C CA    . HIS A 1 431 ? -42.448 -3.456  -18.435  1.00 42.60  ? 431 HIS A CA    1 
ATOM   3349  C C     . HIS A 1 431 ? -43.177 -4.125  -19.584  1.00 37.89  ? 431 HIS A C     1 
ATOM   3350  O O     . HIS A 1 431 ? -44.246 -4.699  -19.373  1.00 41.55  ? 431 HIS A O     1 
ATOM   3351  C CB    . HIS A 1 431 ? -41.807 -4.547  -17.574  1.00 41.02  ? 431 HIS A CB    1 
ATOM   3352  C CG    . HIS A 1 431 ? -41.345 -4.003  -16.287  1.00 37.10  ? 431 HIS A CG    1 
ATOM   3353  N ND1   . HIS A 1 431 ? -40.067 -4.188  -15.855  1.00 36.57  ? 431 HIS A ND1   1 
ATOM   3354  C CD2   . HIS A 1 431 ? -41.980 -3.294  -15.353  1.00 37.99  ? 431 HIS A CD2   1 
ATOM   3355  C CE1   . HIS A 1 431 ? -39.952 -3.614  -14.672  1.00 42.83  ? 431 HIS A CE1   1 
ATOM   3356  N NE2   . HIS A 1 431 ? -41.106 -3.058  -14.360  1.00 40.77  ? 431 HIS A NE2   1 
ATOM   3357  N N     . HIS A 1 432 ? -42.596 -3.984  -20.782  1.00 40.30  ? 432 HIS A N     1 
ATOM   3358  C CA    . HIS A 1 432 ? -42.882 -4.860  -21.907  1.00 42.11  ? 432 HIS A CA    1 
ATOM   3359  C C     . HIS A 1 432 ? -41.982 -6.092  -21.808  1.00 39.46  ? 432 HIS A C     1 
ATOM   3360  O O     . HIS A 1 432 ? -40.793 -6.014  -22.100  1.00 38.83  ? 432 HIS A O     1 
ATOM   3361  C CB    . HIS A 1 432 ? -42.693 -4.124  -23.235  1.00 40.84  ? 432 HIS A CB    1 
ATOM   3362  C CG    . HIS A 1 432 ? -42.947 -5.015  -24.423  1.00 46.83  ? 432 HIS A CG    1 
ATOM   3363  N ND1   . HIS A 1 432 ? -41.977 -5.802  -25.008  1.00 45.70  ? 432 HIS A ND1   1 
ATOM   3364  C CD2   . HIS A 1 432 ? -44.092 -5.307  -25.057  1.00 44.79  ? 432 HIS A CD2   1 
ATOM   3365  C CE1   . HIS A 1 432 ? -42.532 -6.520  -25.969  1.00 49.03  ? 432 HIS A CE1   1 
ATOM   3366  N NE2   . HIS A 1 432 ? -43.809 -6.226  -26.020  1.00 45.93  ? 432 HIS A NE2   1 
ATOM   3367  N N     . VAL A 1 433 ? -42.563 -7.224  -21.396  1.00 37.35  ? 433 VAL A N     1 
ATOM   3368  C CA    . VAL A 1 433 ? -41.834 -8.482  -21.299  1.00 40.16  ? 433 VAL A CA    1 
ATOM   3369  C C     . VAL A 1 433 ? -42.019 -9.330  -22.578  1.00 38.44  ? 433 VAL A C     1 
ATOM   3370  O O     . VAL A 1 433 ? -43.125 -9.662  -22.982  1.00 32.86  ? 433 VAL A O     1 
ATOM   3371  C CB    . VAL A 1 433 ? -42.224 -9.271  -20.033  1.00 40.40  ? 433 VAL A CB    1 
ATOM   3372  C CG1   . VAL A 1 433 ? -41.372 -10.531 -19.874  1.00 38.74  ? 433 VAL A CG1   1 
ATOM   3373  C CG2   . VAL A 1 433 ? -42.135 -8.423  -18.763  1.00 41.55  ? 433 VAL A CG2   1 
ATOM   3374  N N     . THR A 1 434 ? -40.890 -9.643  -23.210  1.00 37.90  ? 434 THR A N     1 
ATOM   3375  C CA    . THR A 1 434 ? -40.783 -10.490 -24.374  1.00 45.09  ? 434 THR A CA    1 
ATOM   3376  C C     . THR A 1 434 ? -40.323 -11.849 -23.865  1.00 43.71  ? 434 THR A C     1 
ATOM   3377  O O     . THR A 1 434 ? -39.308 -11.908 -23.184  1.00 43.67  ? 434 THR A O     1 
ATOM   3378  C CB    . THR A 1 434 ? -39.711 -9.973  -25.351  1.00 45.71  ? 434 THR A CB    1 
ATOM   3379  O OG1   . THR A 1 434 ? -39.888 -8.593  -25.643  1.00 48.89  ? 434 THR A OG1   1 
ATOM   3380  C CG2   . THR A 1 434 ? -39.694 -10.729 -26.661  1.00 50.05  ? 434 THR A CG2   1 
ATOM   3381  N N     . VAL A 1 435 ? -41.053 -12.924 -24.172  1.00 44.63  ? 435 VAL A N     1 
ATOM   3382  C CA    . VAL A 1 435 ? -40.532 -14.239 -23.839  1.00 47.14  ? 435 VAL A CA    1 
ATOM   3383  C C     . VAL A 1 435 ? -40.373 -15.004 -25.142  1.00 40.27  ? 435 VAL A C     1 
ATOM   3384  O O     . VAL A 1 435 ? -41.229 -14.931 -26.012  1.00 36.27  ? 435 VAL A O     1 
ATOM   3385  C CB    . VAL A 1 435 ? -41.331 -14.949 -22.723  1.00 48.38  ? 435 VAL A CB    1 
ATOM   3386  C CG1   . VAL A 1 435 ? -42.547 -14.141 -22.299  1.00 50.00  ? 435 VAL A CG1   1 
ATOM   3387  C CG2   . VAL A 1 435 ? -41.691 -16.391 -23.035  1.00 46.57  ? 435 VAL A CG2   1 
ATOM   3388  N N     . ILE A 1 436 ? -39.191 -15.583 -25.321  1.00 37.59  ? 436 ILE A N     1 
ATOM   3389  C CA    . ILE A 1 436 ? -38.903 -16.314 -26.544  1.00 47.75  ? 436 ILE A CA    1 
ATOM   3390  C C     . ILE A 1 436 ? -38.608 -17.773 -26.214  1.00 47.11  ? 436 ILE A C     1 
ATOM   3391  O O     . ILE A 1 436 ? -37.578 -18.068 -25.626  1.00 42.10  ? 436 ILE A O     1 
ATOM   3392  C CB    . ILE A 1 436 ? -37.720 -15.726 -27.315  1.00 48.88  ? 436 ILE A CB    1 
ATOM   3393  C CG1   . ILE A 1 436 ? -37.750 -14.198 -27.302  1.00 52.41  ? 436 ILE A CG1   1 
ATOM   3394  C CG2   . ILE A 1 436 ? -37.693 -16.314 -28.726  1.00 56.41  ? 436 ILE A CG2   1 
ATOM   3395  C CD1   . ILE A 1 436 ? -36.398 -13.587 -27.502  1.00 52.57  ? 436 ILE A CD1   1 
ATOM   3396  N N     . VAL A 1 437 ? -39.513 -18.658 -26.644  1.00 44.57  ? 437 VAL A N     1 
ATOM   3397  C CA    . VAL A 1 437 ? -39.340 -20.094 -26.538  1.00 45.22  ? 437 VAL A CA    1 
ATOM   3398  C C     . VAL A 1 437 ? -38.525 -20.571 -27.733  1.00 43.82  ? 437 VAL A C     1 
ATOM   3399  O O     . VAL A 1 437 ? -38.836 -20.223 -28.875  1.00 45.97  ? 437 VAL A O     1 
ATOM   3400  C CB    . VAL A 1 437 ? -40.725 -20.747 -26.506  1.00 46.69  ? 437 VAL A CB    1 
ATOM   3401  C CG1   . VAL A 1 437 ? -40.640 -22.244 -26.362  1.00 53.19  ? 437 VAL A CG1   1 
ATOM   3402  C CG2   . VAL A 1 437 ? -41.572 -20.155 -25.390  1.00 49.38  ? 437 VAL A CG2   1 
ATOM   3403  N N     . TYR A 1 438 ? -37.457 -21.324 -27.468  1.00 43.32  ? 438 TYR A N     1 
ATOM   3404  C CA    . TYR A 1 438 ? -36.548 -21.747 -28.527  1.00 50.62  ? 438 TYR A CA    1 
ATOM   3405  C C     . TYR A 1 438 ? -36.086 -23.167 -28.249  1.00 50.02  ? 438 TYR A C     1 
ATOM   3406  O O     . TYR A 1 438 ? -36.138 -23.626 -27.114  1.00 49.26  ? 438 TYR A O     1 
ATOM   3407  C CB    . TYR A 1 438 ? -35.323 -20.827 -28.661  1.00 53.27  ? 438 TYR A CB    1 
ATOM   3408  C CG    . TYR A 1 438 ? -34.405 -20.795 -27.465  1.00 50.24  ? 438 TYR A CG    1 
ATOM   3409  C CD1   . TYR A 1 438 ? -34.854 -20.350 -26.236  1.00 60.07  ? 438 TYR A CD1   1 
ATOM   3410  C CD2   . TYR A 1 438 ? -33.099 -21.240 -27.541  1.00 53.69  ? 438 TYR A CD2   1 
ATOM   3411  C CE1   . TYR A 1 438 ? -34.042 -20.352 -25.112  1.00 70.77  ? 438 TYR A CE1   1 
ATOM   3412  C CE2   . TYR A 1 438 ? -32.265 -21.238 -26.426  1.00 63.35  ? 438 TYR A CE2   1 
ATOM   3413  C CZ    . TYR A 1 438 ? -32.735 -20.797 -25.200  1.00 66.13  ? 438 TYR A CZ    1 
ATOM   3414  O OH    . TYR A 1 438 ? -31.958 -20.764 -24.058  1.00 63.01  ? 438 TYR A OH    1 
ATOM   3415  N N     . ASP A 1 439 ? -35.589 -23.817 -29.300  1.00 58.60  ? 439 ASP A N     1 
ATOM   3416  C CA    . ASP A 1 439 ? -35.060 -25.164 -29.213  1.00 55.03  ? 439 ASP A CA    1 
ATOM   3417  C C     . ASP A 1 439 ? -33.606 -25.141 -28.739  1.00 56.43  ? 439 ASP A C     1 
ATOM   3418  O O     . ASP A 1 439 ? -32.702 -24.951 -29.549  1.00 51.20  ? 439 ASP A O     1 
ATOM   3419  C CB    . ASP A 1 439 ? -35.146 -25.827 -30.581  1.00 52.40  ? 439 ASP A CB    1 
ATOM   3420  C CG    . ASP A 1 439 ? -34.670 -27.258 -30.555  1.00 53.85  ? 439 ASP A CG    1 
ATOM   3421  O OD1   . ASP A 1 439 ? -34.173 -27.686 -29.484  1.00 56.56  ? 439 ASP A OD1   1 
ATOM   3422  O OD2   . ASP A 1 439 ? -34.807 -27.919 -31.600  1.00 56.08  ? 439 ASP A OD2   1 
ATOM   3423  N N     . LYS A 1 440 ? -33.399 -25.429 -27.446  1.00 58.49  ? 440 LYS A N     1 
ATOM   3424  C CA    . LYS A 1 440 ? -32.117 -25.272 -26.771  1.00 66.02  ? 440 LYS A CA    1 
ATOM   3425  C C     . LYS A 1 440 ? -31.095 -26.291 -27.275  1.00 67.54  ? 440 LYS A C     1 
ATOM   3426  O O     . LYS A 1 440 ? -29.926 -26.175 -26.922  1.00 67.34  ? 440 LYS A O     1 
ATOM   3427  C CB    . LYS A 1 440 ? -32.279 -25.443 -25.251  1.00 70.71  ? 440 LYS A CB    1 
ATOM   3428  C CG    . LYS A 1 440 ? -32.843 -26.804 -24.849  1.00 89.32  ? 440 LYS A CG    1 
ATOM   3429  C CD    . LYS A 1 440 ? -32.711 -27.199 -23.393  1.00 100.58 ? 440 LYS A CD    1 
ATOM   3430  C CE    . LYS A 1 440 ? -33.343 -28.551 -23.116  1.00 101.79 ? 440 LYS A CE    1 
ATOM   3431  N NZ    . LYS A 1 440 ? -33.678 -28.723 -21.682  1.00 104.33 ? 440 LYS A NZ    1 
ATOM   3432  N N     . THR A 1 441 ? -31.542 -27.305 -28.038  1.00 66.53  ? 441 THR A N     1 
ATOM   3433  C CA    . THR A 1 441 ? -30.701 -28.433 -28.426  1.00 65.39  ? 441 THR A CA    1 
ATOM   3434  C C     . THR A 1 441 ? -30.145 -28.246 -29.841  1.00 71.60  ? 441 THR A C     1 
ATOM   3435  O O     . THR A 1 441 ? -29.277 -29.000 -30.277  1.00 79.27  ? 441 THR A O     1 
ATOM   3436  C CB    . THR A 1 441 ? -31.464 -29.770 -28.329  1.00 59.72  ? 441 THR A CB    1 
ATOM   3437  O OG1   . THR A 1 441 ? -32.521 -29.813 -29.289  1.00 53.01  ? 441 THR A OG1   1 
ATOM   3438  C CG2   . THR A 1 441 ? -32.061 -30.033 -26.961  1.00 60.36  ? 441 THR A CG2   1 
ATOM   3439  N N     . ASP A 1 442 ? -30.663 -27.247 -30.563  1.00 74.81  ? 442 ASP A N     1 
ATOM   3440  C CA    . ASP A 1 442 ? -30.330 -27.032 -31.962  1.00 64.87  ? 442 ASP A CA    1 
ATOM   3441  C C     . ASP A 1 442 ? -29.387 -25.831 -32.040  1.00 64.75  ? 442 ASP A C     1 
ATOM   3442  O O     . ASP A 1 442 ? -29.830 -24.727 -31.778  1.00 60.64  ? 442 ASP A O     1 
ATOM   3443  C CB    . ASP A 1 442 ? -31.626 -26.851 -32.761  1.00 54.31  ? 442 ASP A CB    1 
ATOM   3444  C CG    . ASP A 1 442 ? -31.425 -26.382 -34.191  1.00 60.41  ? 442 ASP A CG    1 
ATOM   3445  O OD1   . ASP A 1 442 ? -30.275 -26.125 -34.563  1.00 69.75  ? 442 ASP A OD1   1 
ATOM   3446  O OD2   . ASP A 1 442 ? -32.424 -26.269 -34.922  1.00 62.35  ? 442 ASP A OD2   1 
ATOM   3447  N N     . PRO A 1 443 ? -28.089 -25.976 -32.414  1.00 68.48  ? 443 PRO A N     1 
ATOM   3448  C CA    . PRO A 1 443 ? -27.152 -24.843 -32.446  1.00 61.81  ? 443 PRO A CA    1 
ATOM   3449  C C     . PRO A 1 443 ? -27.470 -23.720 -33.438  1.00 60.70  ? 443 PRO A C     1 
ATOM   3450  O O     . PRO A 1 443 ? -27.055 -22.576 -33.237  1.00 61.50  ? 443 PRO A O     1 
ATOM   3451  C CB    . PRO A 1 443 ? -25.795 -25.467 -32.819  1.00 59.72  ? 443 PRO A CB    1 
ATOM   3452  C CG    . PRO A 1 443 ? -25.968 -26.934 -32.521  1.00 66.73  ? 443 PRO A CG    1 
ATOM   3453  C CD    . PRO A 1 443 ? -27.431 -27.233 -32.796  1.00 68.74  ? 443 PRO A CD    1 
ATOM   3454  N N     . ASP A 1 444 ? -28.202 -24.035 -34.509  1.00 54.51  ? 444 ASP A N     1 
ATOM   3455  C CA    . ASP A 1 444 ? -28.596 -23.009 -35.457  1.00 60.12  ? 444 ASP A CA    1 
ATOM   3456  C C     . ASP A 1 444 ? -29.643 -22.084 -34.847  1.00 52.32  ? 444 ASP A C     1 
ATOM   3457  O O     . ASP A 1 444 ? -29.615 -20.900 -35.118  1.00 55.61  ? 444 ASP A O     1 
ATOM   3458  C CB    . ASP A 1 444 ? -29.079 -23.591 -36.787  1.00 65.44  ? 444 ASP A CB    1 
ATOM   3459  C CG    . ASP A 1 444 ? -27.975 -24.323 -37.530  1.00 74.81  ? 444 ASP A CG    1 
ATOM   3460  O OD1   . ASP A 1 444 ? -26.804 -23.858 -37.471  1.00 70.54  ? 444 ASP A OD1   1 
ATOM   3461  O OD2   . ASP A 1 444 ? -28.295 -25.339 -38.169  1.00 83.18  ? 444 ASP A OD2   1 
ATOM   3462  N N     . GLU A 1 445 ? -30.570 -22.609 -34.047  1.00 52.30  ? 445 GLU A N     1 
ATOM   3463  C CA    . GLU A 1 445 ? -31.530 -21.770 -33.343  1.00 51.95  ? 445 GLU A CA    1 
ATOM   3464  C C     . GLU A 1 445 ? -30.870 -21.041 -32.167  1.00 50.82  ? 445 GLU A C     1 
ATOM   3465  O O     . GLU A 1 445 ? -31.306 -19.973 -31.792  1.00 53.31  ? 445 GLU A O     1 
ATOM   3466  C CB    . GLU A 1 445 ? -32.696 -22.619 -32.848  1.00 54.12  ? 445 GLU A CB    1 
ATOM   3467  C CG    . GLU A 1 445 ? -33.651 -23.009 -33.948  1.00 61.95  ? 445 GLU A CG    1 
ATOM   3468  C CD    . GLU A 1 445 ? -34.979 -22.283 -33.854  1.00 80.38  ? 445 GLU A CD    1 
ATOM   3469  O OE1   . GLU A 1 445 ? -35.686 -22.443 -32.772  1.00 74.71  ? 445 GLU A OE1   1 
ATOM   3470  O OE2   . GLU A 1 445 ? -35.308 -21.571 -34.852  1.00 73.81  ? 445 GLU A OE2   1 
ATOM   3471  N N     . ARG A 1 446 ? -29.811 -21.592 -31.570  1.00 49.66  ? 446 ARG A N     1 
ATOM   3472  C CA    . ARG A 1 446 ? -29.079 -20.853 -30.553  1.00 54.67  ? 446 ARG A CA    1 
ATOM   3473  C C     . ARG A 1 446 ? -28.407 -19.634 -31.176  1.00 49.27  ? 446 ARG A C     1 
ATOM   3474  O O     . ARG A 1 446 ? -28.450 -18.565 -30.598  1.00 60.91  ? 446 ARG A O     1 
ATOM   3475  C CB    . ARG A 1 446 ? -28.069 -21.730 -29.799  1.00 56.20  ? 446 ARG A CB    1 
ATOM   3476  C CG    . ARG A 1 446 ? -28.725 -22.767 -28.890  1.00 58.42  ? 446 ARG A CG    1 
ATOM   3477  C CD    . ARG A 1 446 ? -27.794 -23.449 -27.900  1.00 60.76  ? 446 ARG A CD    1 
ATOM   3478  N NE    . ARG A 1 446 ? -26.672 -24.136 -28.522  1.00 66.19  ? 446 ARG A NE    1 
ATOM   3479  C CZ    . ARG A 1 446 ? -26.382 -25.434 -28.398  1.00 67.66  ? 446 ARG A CZ    1 
ATOM   3480  N NH1   . ARG A 1 446 ? -27.188 -26.250 -27.744  1.00 62.70  ? 446 ARG A NH1   1 
ATOM   3481  N NH2   . ARG A 1 446 ? -25.279 -25.915 -28.955  1.00 69.25  ? 446 ARG A NH2   1 
ATOM   3482  N N     . LYS A 1 447 ? -27.803 -19.762 -32.356  1.00 51.80  ? 447 LYS A N     1 
ATOM   3483  C CA    . LYS A 1 447 ? -27.137 -18.608 -32.949  1.00 53.87  ? 447 LYS A CA    1 
ATOM   3484  C C     . LYS A 1 447 ? -28.190 -17.528 -33.168  1.00 51.74  ? 447 LYS A C     1 
ATOM   3485  O O     . LYS A 1 447 ? -27.977 -16.386 -32.768  1.00 56.49  ? 447 LYS A O     1 
ATOM   3486  C CB    . LYS A 1 447 ? -26.343 -18.984 -34.209  1.00 54.77  ? 447 LYS A CB    1 
ATOM   3487  C CG    . LYS A 1 447 ? -25.860 -17.841 -35.100  1.00 57.59  ? 447 LYS A CG    1 
ATOM   3488  C CD    . LYS A 1 447 ? -24.975 -16.775 -34.457  1.00 62.43  ? 447 LYS A CD    1 
ATOM   3489  C CE    . LYS A 1 447 ? -23.556 -16.788 -34.992  1.00 71.51  ? 447 LYS A CE    1 
ATOM   3490  N NZ    . LYS A 1 447 ? -22.681 -15.770 -34.347  1.00 66.15  ? 447 LYS A NZ    1 
ATOM   3491  N N     . LYS A 1 448 ? -29.339 -17.932 -33.724  1.00 48.74  ? 448 LYS A N     1 
ATOM   3492  C CA    . LYS A 1 448 ? -30.445 -17.031 -34.047  1.00 53.46  ? 448 LYS A CA    1 
ATOM   3493  C C     . LYS A 1 448 ? -30.948 -16.282 -32.815  1.00 49.46  ? 448 LYS A C     1 
ATOM   3494  O O     . LYS A 1 448 ? -31.121 -15.071 -32.873  1.00 52.33  ? 448 LYS A O     1 
ATOM   3495  C CB    . LYS A 1 448 ? -31.634 -17.780 -34.670  1.00 48.20  ? 448 LYS A CB    1 
ATOM   3496  C CG    . LYS A 1 448 ? -31.460 -18.079 -36.155  1.00 51.79  ? 448 LYS A CG    1 
ATOM   3497  C CD    . LYS A 1 448 ? -32.459 -19.059 -36.710  1.00 48.79  ? 448 LYS A CD    1 
ATOM   3498  C CE    . LYS A 1 448 ? -33.856 -18.482 -36.755  1.00 54.90  ? 448 LYS A CE    1 
ATOM   3499  N NZ    . LYS A 1 448 ? -34.872 -19.517 -37.049  1.00 53.49  ? 448 LYS A NZ    1 
ATOM   3500  N N     . LEU A 1 449 ? -31.248 -17.019 -31.745  1.00 45.92  ? 449 LEU A N     1 
ATOM   3501  C CA    . LEU A 1 449 ? -31.780 -16.434 -30.530  1.00 51.64  ? 449 LEU A CA    1 
ATOM   3502  C C     . LEU A 1 449 ? -30.789 -15.453 -29.899  1.00 47.64  ? 449 LEU A C     1 
ATOM   3503  O O     . LEU A 1 449 ? -31.210 -14.402 -29.453  1.00 45.44  ? 449 LEU A O     1 
ATOM   3504  C CB    . LEU A 1 449 ? -32.100 -17.529 -29.513  1.00 54.00  ? 449 LEU A CB    1 
ATOM   3505  C CG    . LEU A 1 449 ? -32.351 -16.956 -28.119  1.00 54.95  ? 449 LEU A CG    1 
ATOM   3506  C CD1   . LEU A 1 449 ? -33.818 -16.615 -27.940  1.00 53.22  ? 449 LEU A CD1   1 
ATOM   3507  C CD2   . LEU A 1 449 ? -31.860 -17.892 -27.043  1.00 63.60  ? 449 LEU A CD2   1 
ATOM   3508  N N     . ASP A 1 450 ? -29.501 -15.817 -29.815  1.00 49.25  ? 450 ASP A N     1 
ATOM   3509  C CA    . ASP A 1 450 ? -28.481 -14.945 -29.247  1.00 56.10  ? 450 ASP A CA    1 
ATOM   3510  C C     . ASP A 1 450 ? -28.436 -13.609 -30.001  1.00 53.38  ? 450 ASP A C     1 
ATOM   3511  O O     . ASP A 1 450 ? -28.448 -12.541 -29.388  1.00 52.96  ? 450 ASP A O     1 
ATOM   3512  C CB    . ASP A 1 450 ? -27.121 -15.644 -29.205  1.00 62.08  ? 450 ASP A CB    1 
ATOM   3513  C CG    . ASP A 1 450 ? -26.032 -14.890 -28.443  1.00 72.75  ? 450 ASP A CG    1 
ATOM   3514  O OD1   . ASP A 1 450 ? -26.275 -14.477 -27.276  1.00 79.18  ? 450 ASP A OD1   1 
ATOM   3515  O OD2   . ASP A 1 450 ? -24.918 -14.755 -28.995  1.00 73.65  ? 450 ASP A OD2   1 
ATOM   3516  N N     . GLU A 1 451 ? -28.448 -13.666 -31.333  1.00 50.74  ? 451 GLU A N     1 
ATOM   3517  C CA    . GLU A 1 451 ? -28.377 -12.470 -32.167  1.00 50.39  ? 451 GLU A CA    1 
ATOM   3518  C C     . GLU A 1 451 ? -29.606 -11.591 -31.937  1.00 44.80  ? 451 GLU A C     1 
ATOM   3519  O O     . GLU A 1 451 ? -29.456 -10.414 -31.614  1.00 49.04  ? 451 GLU A O     1 
ATOM   3520  C CB    . GLU A 1 451 ? -28.190 -12.862 -33.636  1.00 43.60  ? 451 GLU A CB    1 
ATOM   3521  C CG    . GLU A 1 451 ? -28.391 -11.726 -34.600  1.00 43.73  ? 451 GLU A CG    1 
ATOM   3522  C CD    . GLU A 1 451 ? -28.313 -12.161 -36.054  1.00 49.94  ? 451 GLU A CD    1 
ATOM   3523  O OE1   . GLU A 1 451 ? -27.271 -12.760 -36.420  1.00 45.91  ? 451 GLU A OE1   1 
ATOM   3524  O OE2   . GLU A 1 451 ? -29.315 -11.939 -36.804  1.00 50.06  ? 451 GLU A OE2   1 
ATOM   3525  N N     . LEU A 1 452 ? -30.796 -12.192 -32.050  1.00 38.88  ? 452 LEU A N     1 
ATOM   3526  C CA    . LEU A 1 452 ? -32.080 -11.536 -31.794  1.00 40.63  ? 452 LEU A CA    1 
ATOM   3527  C C     . LEU A 1 452 ? -32.086 -10.815 -30.445  1.00 36.40  ? 452 LEU A C     1 
ATOM   3528  O O     . LEU A 1 452 ? -32.473 -9.656  -30.375  1.00 30.38  ? 452 LEU A O     1 
ATOM   3529  C CB    . LEU A 1 452 ? -33.183 -12.600 -31.815  1.00 42.03  ? 452 LEU A CB    1 
ATOM   3530  C CG    . LEU A 1 452 ? -34.581 -12.145 -31.395  1.00 43.35  ? 452 LEU A CG    1 
ATOM   3531  C CD1   . LEU A 1 452 ? -35.044 -10.963 -32.225  1.00 42.22  ? 452 LEU A CD1   1 
ATOM   3532  C CD2   . LEU A 1 452 ? -35.579 -13.289 -31.533  1.00 37.95  ? 452 LEU A CD2   1 
ATOM   3533  N N     . PHE A 1 453 ? -31.627 -11.504 -29.393  1.00 35.82  ? 453 PHE A N     1 
ATOM   3534  C CA    . PHE A 1 453 ? -31.619 -10.946 -28.059  1.00 38.50  ? 453 PHE A CA    1 
ATOM   3535  C C     . PHE A 1 453 ? -30.752 -9.696  -28.003  1.00 39.47  ? 453 PHE A C     1 
ATOM   3536  O O     . PHE A 1 453 ? -31.216 -8.655  -27.529  1.00 38.26  ? 453 PHE A O     1 
ATOM   3537  C CB    . PHE A 1 453 ? -31.102 -11.951 -27.031  1.00 45.02  ? 453 PHE A CB    1 
ATOM   3538  C CG    . PHE A 1 453 ? -31.274 -11.477 -25.610  1.00 44.97  ? 453 PHE A CG    1 
ATOM   3539  C CD1   . PHE A 1 453 ? -30.319 -10.688 -25.002  1.00 43.62  ? 453 PHE A CD1   1 
ATOM   3540  C CD2   . PHE A 1 453 ? -32.441 -11.746 -24.918  1.00 48.15  ? 453 PHE A CD2   1 
ATOM   3541  C CE1   . PHE A 1 453 ? -30.498 -10.233 -23.704  1.00 49.82  ? 453 PHE A CE1   1 
ATOM   3542  C CE2   . PHE A 1 453 ? -32.614 -11.298 -23.615  1.00 52.15  ? 453 PHE A CE2   1 
ATOM   3543  C CZ    . PHE A 1 453 ? -31.649 -10.534 -23.012  1.00 46.73  ? 453 PHE A CZ    1 
ATOM   3544  N N     . ASN A 1 454 ? -29.510 -9.823  -28.492  1.00 36.44  ? 454 ASN A N     1 
ATOM   3545  C CA    . ASN A 1 454 ? -28.598 -8.697  -28.585  1.00 37.85  ? 454 ASN A CA    1 
ATOM   3546  C C     . ASN A 1 454 ? -29.272 -7.518  -29.302  1.00 41.37  ? 454 ASN A C     1 
ATOM   3547  O O     . ASN A 1 454 ? -29.195 -6.378  -28.846  1.00 39.88  ? 454 ASN A O     1 
ATOM   3548  C CB    . ASN A 1 454 ? -27.270 -9.080  -29.246  1.00 37.64  ? 454 ASN A CB    1 
ATOM   3549  C CG    . ASN A 1 454 ? -26.316 -9.762  -28.294  1.00 38.30  ? 454 ASN A CG    1 
ATOM   3550  O OD1   . ASN A 1 454 ? -25.920 -9.208  -27.268  1.00 60.86  ? 454 ASN A OD1   1 
ATOM   3551  N ND2   . ASN A 1 454 ? -25.911 -10.961 -28.632  1.00 41.68  ? 454 ASN A ND2   1 
ATOM   3552  N N     . ILE A 1 455 ? -29.969 -7.773  -30.411  1.00 39.94  ? 455 ILE A N     1 
ATOM   3553  C CA    . ILE A 1 455 ? -30.538 -6.670  -31.167  1.00 37.64  ? 455 ILE A CA    1 
ATOM   3554  C C     . ILE A 1 455 ? -31.677 -6.057  -30.362  1.00 37.16  ? 455 ILE A C     1 
ATOM   3555  O O     . ILE A 1 455 ? -31.860 -4.829  -30.340  1.00 39.88  ? 455 ILE A O     1 
ATOM   3556  C CB    . ILE A 1 455 ? -30.949 -7.120  -32.588  1.00 36.55  ? 455 ILE A CB    1 
ATOM   3557  C CG1   . ILE A 1 455 ? -29.702 -7.333  -33.441  1.00 39.31  ? 455 ILE A CG1   1 
ATOM   3558  C CG2   . ILE A 1 455 ? -31.922 -6.159  -33.271  1.00 37.62  ? 455 ILE A CG2   1 
ATOM   3559  C CD1   . ILE A 1 455 ? -29.978 -7.983  -34.783  1.00 45.06  ? 455 ILE A CD1   1 
ATOM   3560  N N     . LEU A 1 456 ? -32.497 -6.901  -29.742  1.00 34.60  ? 456 LEU A N     1 
ATOM   3561  C CA    . LEU A 1 456 ? -33.638 -6.333  -29.051  1.00 37.19  ? 456 LEU A CA    1 
ATOM   3562  C C     . LEU A 1 456 ? -33.114 -5.346  -27.991  1.00 34.94  ? 456 LEU A C     1 
ATOM   3563  O O     . LEU A 1 456 ? -33.565 -4.205  -27.912  1.00 34.76  ? 456 LEU A O     1 
ATOM   3564  C CB    . LEU A 1 456 ? -34.487 -7.443  -28.423  1.00 37.96  ? 456 LEU A CB    1 
ATOM   3565  C CG    . LEU A 1 456 ? -35.282 -8.330  -29.372  1.00 40.66  ? 456 LEU A CG    1 
ATOM   3566  C CD1   . LEU A 1 456 ? -36.001 -9.406  -28.571  1.00 45.27  ? 456 LEU A CD1   1 
ATOM   3567  C CD2   . LEU A 1 456 ? -36.282 -7.559  -30.211  1.00 36.67  ? 456 LEU A CD2   1 
ATOM   3568  N N     . VAL A 1 457 ? -32.142 -5.798  -27.197  1.00 34.87  ? 457 VAL A N     1 
ATOM   3569  C CA    . VAL A 1 457 ? -31.557 -5.009  -26.120  1.00 38.33  ? 457 VAL A CA    1 
ATOM   3570  C C     . VAL A 1 457 ? -31.065 -3.679  -26.682  1.00 39.26  ? 457 VAL A C     1 
ATOM   3571  O O     . VAL A 1 457 ? -31.435 -2.613  -26.175  1.00 39.77  ? 457 VAL A O     1 
ATOM   3572  C CB    . VAL A 1 457 ? -30.431 -5.786  -25.397  1.00 41.67  ? 457 VAL A CB    1 
ATOM   3573  C CG1   . VAL A 1 457 ? -29.641 -4.910  -24.448  1.00 47.59  ? 457 VAL A CG1   1 
ATOM   3574  C CG2   . VAL A 1 457 ? -30.974 -6.969  -24.614  1.00 42.01  ? 457 VAL A CG2   1 
ATOM   3575  N N     . ASP A 1 458 ? -30.252 -3.762  -27.746  1.00 38.43  ? 458 ASP A N     1 
ATOM   3576  C CA    . ASP A 1 458 ? -29.716 -2.602  -28.439  1.00 37.11  ? 458 ASP A CA    1 
ATOM   3577  C C     . ASP A 1 458 ? -30.827 -1.625  -28.834  1.00 35.55  ? 458 ASP A C     1 
ATOM   3578  O O     . ASP A 1 458 ? -30.741 -0.449  -28.500  1.00 38.34  ? 458 ASP A O     1 
ATOM   3579  C CB    . ASP A 1 458 ? -28.881 -3.045  -29.633  1.00 39.08  ? 458 ASP A CB    1 
ATOM   3580  C CG    . ASP A 1 458 ? -27.532 -3.664  -29.286  1.00 40.73  ? 458 ASP A CG    1 
ATOM   3581  O OD1   . ASP A 1 458 ? -27.046 -3.446  -28.150  1.00 48.29  ? 458 ASP A OD1   1 
ATOM   3582  O OD2   . ASP A 1 458 ? -26.964 -4.358  -30.162  1.00 39.65  ? 458 ASP A OD2   1 
ATOM   3583  N N     . GLU A 1 459 ? -31.919 -2.100  -29.444  1.00 38.71  ? 459 GLU A N     1 
ATOM   3584  C CA    . GLU A 1 459 ? -32.936 -1.181  -29.945  1.00 38.08  ? 459 GLU A CA    1 
ATOM   3585  C C     . GLU A 1 459 ? -33.788 -0.612  -28.807  1.00 38.44  ? 459 GLU A C     1 
ATOM   3586  O O     . GLU A 1 459 ? -34.158 0.564   -28.831  1.00 43.91  ? 459 GLU A O     1 
ATOM   3587  C CB    . GLU A 1 459 ? -33.706 -1.834  -31.087  1.00 38.15  ? 459 GLU A CB    1 
ATOM   3588  C CG    . GLU A 1 459 ? -32.781 -2.077  -32.276  1.00 42.13  ? 459 GLU A CG    1 
ATOM   3589  C CD    . GLU A 1 459 ? -33.312 -2.729  -33.549  1.00 44.48  ? 459 GLU A CD    1 
ATOM   3590  O OE1   . GLU A 1 459 ? -34.424 -3.298  -33.539  1.00 40.63  ? 459 GLU A OE1   1 
ATOM   3591  O OE2   . GLU A 1 459 ? -32.595 -2.643  -34.564  1.00 44.73  ? 459 GLU A OE2   1 
ATOM   3592  N N     . ALA A 1 460 ? -34.013 -1.400  -27.760  1.00 38.44  ? 460 ALA A N     1 
ATOM   3593  C CA    . ALA A 1 460 ? -34.762 -0.944  -26.602  1.00 38.08  ? 460 ALA A CA    1 
ATOM   3594  C C     . ALA A 1 460 ? -33.986 0.131   -25.827  1.00 39.67  ? 460 ALA A C     1 
ATOM   3595  O O     . ALA A 1 460 ? -34.519 1.189   -25.498  1.00 36.71  ? 460 ALA A O     1 
ATOM   3596  C CB    . ALA A 1 460 ? -35.072 -2.143  -25.746  1.00 41.14  ? 460 ALA A CB    1 
ATOM   3597  N N     . ALA A 1 461 ? -32.700 -0.102  -25.544  1.00 43.52  ? 461 ALA A N     1 
ATOM   3598  C CA    . ALA A 1 461 ? -31.911 0.895   -24.825  1.00 40.87  ? 461 ALA A CA    1 
ATOM   3599  C C     . ALA A 1 461 ? -31.954 2.255   -25.545  1.00 44.08  ? 461 ALA A C     1 
ATOM   3600  O O     . ALA A 1 461 ? -32.138 3.304   -24.929  1.00 43.75  ? 461 ALA A O     1 
ATOM   3601  C CB    . ALA A 1 461 ? -30.498 0.391   -24.627  1.00 37.73  ? 461 ALA A CB    1 
ATOM   3602  N N     . ALA A 1 462 ? -31.826 2.245   -26.873  1.00 47.54  ? 462 ALA A N     1 
ATOM   3603  C CA    . ALA A 1 462 ? -31.756 3.474   -27.650  1.00 43.07  ? 462 ALA A CA    1 
ATOM   3604  C C     . ALA A 1 462 ? -33.021 4.312   -27.520  1.00 41.60  ? 462 ALA A C     1 
ATOM   3605  O O     . ALA A 1 462 ? -33.013 5.485   -27.861  1.00 40.02  ? 462 ALA A O     1 
ATOM   3606  C CB    . ALA A 1 462 ? -31.513 3.138   -29.092  1.00 37.17  ? 462 ALA A CB    1 
ATOM   3607  N N     . GLU A 1 463 ? -34.114 3.691   -27.072  1.00 51.13  ? 463 GLU A N     1 
ATOM   3608  C CA    . GLU A 1 463 ? -35.391 4.379   -26.918  1.00 47.18  ? 463 GLU A CA    1 
ATOM   3609  C C     . GLU A 1 463 ? -35.634 4.695   -25.444  1.00 41.19  ? 463 GLU A C     1 
ATOM   3610  O O     . GLU A 1 463 ? -36.690 5.200   -25.093  1.00 43.32  ? 463 GLU A O     1 
ATOM   3611  C CB    . GLU A 1 463 ? -36.528 3.497   -27.437  1.00 44.73  ? 463 GLU A CB    1 
ATOM   3612  C CG    . GLU A 1 463 ? -36.457 3.159   -28.908  1.00 50.32  ? 463 GLU A CG    1 
ATOM   3613  C CD    . GLU A 1 463 ? -36.882 4.266   -29.864  1.00 55.91  ? 463 GLU A CD    1 
ATOM   3614  O OE1   . GLU A 1 463 ? -37.811 5.021   -29.523  1.00 56.40  ? 463 GLU A OE1   1 
ATOM   3615  O OE2   . GLU A 1 463 ? -36.342 4.319   -30.994  1.00 71.00  ? 463 GLU A OE2   1 
ATOM   3616  N N     . GLY A 1 464 ? -34.695 4.325   -24.576  1.00 39.66  ? 464 GLY A N     1 
ATOM   3617  C CA    . GLY A 1 464 ? -34.763 4.702   -23.173  1.00 46.60  ? 464 GLY A CA    1 
ATOM   3618  C C     . GLY A 1 464 ? -35.159 3.556   -22.242  1.00 44.07  ? 464 GLY A C     1 
ATOM   3619  O O     . GLY A 1 464 ? -35.292 3.758   -21.040  1.00 47.01  ? 464 GLY A O     1 
ATOM   3620  N N     . TYR A 1 465 ? -35.259 2.340   -22.777  1.00 42.44  ? 465 TYR A N     1 
ATOM   3621  C CA    . TYR A 1 465 ? -35.790 1.213   -22.023  1.00 38.15  ? 465 TYR A CA    1 
ATOM   3622  C C     . TYR A 1 465 ? -34.667 0.296   -21.599  1.00 35.51  ? 465 TYR A C     1 
ATOM   3623  O O     . TYR A 1 465 ? -33.981 -0.219  -22.474  1.00 38.47  ? 465 TYR A O     1 
ATOM   3624  C CB    . TYR A 1 465 ? -36.731 0.395   -22.886  1.00 35.72  ? 465 TYR A CB    1 
ATOM   3625  C CG    . TYR A 1 465 ? -37.750 1.238   -23.596  1.00 36.41  ? 465 TYR A CG    1 
ATOM   3626  C CD1   . TYR A 1 465 ? -38.316 2.344   -22.974  1.00 34.52  ? 465 TYR A CD1   1 
ATOM   3627  C CD2   . TYR A 1 465 ? -38.180 0.910   -24.871  1.00 32.95  ? 465 TYR A CD2   1 
ATOM   3628  C CE1   . TYR A 1 465 ? -39.287 3.115   -23.606  1.00 35.08  ? 465 TYR A CE1   1 
ATOM   3629  C CE2   . TYR A 1 465 ? -39.145 1.680   -25.513  1.00 36.87  ? 465 TYR A CE2   1 
ATOM   3630  C CZ    . TYR A 1 465 ? -39.693 2.798   -24.888  1.00 36.61  ? 465 TYR A CZ    1 
ATOM   3631  O OH    . TYR A 1 465 ? -40.682 3.545   -25.508  1.00 35.62  ? 465 TYR A OH    1 
ATOM   3632  N N     . GLY A 1 466 ? -34.490 0.144   -20.278  1.00 33.70  ? 466 GLY A N     1 
ATOM   3633  C CA    . GLY A 1 466 ? -33.373 -0.611  -19.729  1.00 38.59  ? 466 GLY A CA    1 
ATOM   3634  C C     . GLY A 1 466 ? -33.810 -1.818  -18.884  1.00 40.99  ? 466 GLY A C     1 
ATOM   3635  O O     . GLY A 1 466 ? -34.824 -1.766  -18.189  1.00 42.40  ? 466 GLY A O     1 
ATOM   3636  N N     . GLU A 1 467 ? -33.003 -2.890  -18.945  1.00 39.94  ? 467 GLU A N     1 
ATOM   3637  C CA    . GLU A 1 467 ? -33.308 -4.187  -18.375  1.00 37.43  ? 467 GLU A CA    1 
ATOM   3638  C C     . GLU A 1 467 ? -32.985 -4.122  -16.890  1.00 37.72  ? 467 GLU A C     1 
ATOM   3639  O O     . GLU A 1 467 ? -32.079 -3.414  -16.517  1.00 43.08  ? 467 GLU A O     1 
ATOM   3640  C CB    . GLU A 1 467 ? -32.502 -5.274  -19.096  1.00 39.38  ? 467 GLU A CB    1 
ATOM   3641  C CG    . GLU A 1 467 ? -32.677 -6.678  -18.499  1.00 45.25  ? 467 GLU A CG    1 
ATOM   3642  C CD    . GLU A 1 467 ? -34.112 -7.216  -18.475  1.00 52.77  ? 467 GLU A CD    1 
ATOM   3643  O OE1   . GLU A 1 467 ? -34.414 -8.061  -19.387  1.00 48.49  ? 467 GLU A OE1   1 
ATOM   3644  O OE2   . GLU A 1 467 ? -34.939 -6.825  -17.544  1.00 38.39  ? 467 GLU A OE2   1 
ATOM   3645  N N     . TYR A 1 468 ? -33.740 -4.826  -16.043  1.00 40.59  ? 468 TYR A N     1 
ATOM   3646  C CA    . TYR A 1 468 ? -33.483 -4.786  -14.613  1.00 42.90  ? 468 TYR A CA    1 
ATOM   3647  C C     . TYR A 1 468 ? -33.062 -6.143  -14.057  1.00 40.24  ? 468 TYR A C     1 
ATOM   3648  O O     . TYR A 1 468 ? -32.590 -6.205  -12.923  1.00 41.03  ? 468 TYR A O     1 
ATOM   3649  C CB    . TYR A 1 468 ? -34.705 -4.311  -13.842  1.00 42.54  ? 468 TYR A CB    1 
ATOM   3650  C CG    . TYR A 1 468 ? -35.811 -5.320  -13.691  1.00 42.78  ? 468 TYR A CG    1 
ATOM   3651  C CD1   . TYR A 1 468 ? -36.736 -5.519  -14.697  1.00 43.03  ? 468 TYR A CD1   1 
ATOM   3652  C CD2   . TYR A 1 468 ? -35.987 -6.000  -12.502  1.00 41.58  ? 468 TYR A CD2   1 
ATOM   3653  C CE1   . TYR A 1 468 ? -37.776 -6.413  -14.550  1.00 40.45  ? 468 TYR A CE1   1 
ATOM   3654  C CE2   . TYR A 1 468 ? -37.025 -6.894  -12.337  1.00 40.34  ? 468 TYR A CE2   1 
ATOM   3655  C CZ    . TYR A 1 468 ? -37.910 -7.107  -13.367  1.00 39.92  ? 468 TYR A CZ    1 
ATOM   3656  O OH    . TYR A 1 468 ? -38.938 -7.987  -13.207  1.00 50.35  ? 468 TYR A OH    1 
ATOM   3657  N N     . ARG A 1 469 ? -33.222 -7.187  -14.863  1.00 36.24  ? 469 ARG A N     1 
ATOM   3658  C CA    . ARG A 1 469 ? -32.931 -8.554  -14.475  1.00 38.32  ? 469 ARG A CA    1 
ATOM   3659  C C     . ARG A 1 469 ? -32.597 -9.370  -15.717  1.00 38.92  ? 469 ARG A C     1 
ATOM   3660  O O     . ARG A 1 469 ? -33.327 -9.346  -16.693  1.00 39.74  ? 469 ARG A O     1 
ATOM   3661  C CB    . ARG A 1 469 ? -34.172 -9.170  -13.840  1.00 42.90  ? 469 ARG A CB    1 
ATOM   3662  C CG    . ARG A 1 469 ? -33.886 -10.492 -13.151  1.00 54.10  ? 469 ARG A CG    1 
ATOM   3663  C CD    . ARG A 1 469 ? -35.017 -10.926 -12.223  1.00 56.40  ? 469 ARG A CD    1 
ATOM   3664  N NE    . ARG A 1 469 ? -34.658 -12.213 -11.640  1.00 51.87  ? 469 ARG A NE    1 
ATOM   3665  C CZ    . ARG A 1 469 ? -35.529 -13.175 -11.385  1.00 53.01  ? 469 ARG A CZ    1 
ATOM   3666  N NH1   . ARG A 1 469 ? -36.830 -12.913 -11.442  1.00 51.44  ? 469 ARG A NH1   1 
ATOM   3667  N NH2   . ARG A 1 469 ? -35.087 -14.376 -11.038  1.00 51.52  ? 469 ARG A NH2   1 
ATOM   3668  N N     . THR A 1 470 ? -31.512 -10.120 -15.682  1.00 42.56  ? 470 THR A N     1 
ATOM   3669  C CA    . THR A 1 470 ? -31.061 -10.779 -16.888  1.00 48.17  ? 470 THR A CA    1 
ATOM   3670  C C     . THR A 1 470 ? -30.350 -12.109 -16.593  1.00 51.43  ? 470 THR A C     1 
ATOM   3671  O O     . THR A 1 470 ? -30.119 -12.466 -15.442  1.00 49.05  ? 470 THR A O     1 
ATOM   3672  C CB    . THR A 1 470 ? -30.148 -9.832  -17.667  1.00 46.76  ? 470 THR A CB    1 
ATOM   3673  O OG1   . THR A 1 470 ? -30.236 -10.279 -19.024  1.00 43.65  ? 470 THR A OG1   1 
ATOM   3674  C CG2   . THR A 1 470 ? -28.750 -9.826  -17.078  1.00 44.34  ? 470 THR A CG2   1 
ATOM   3675  N N     . HIS A 1 471 ? -30.042 -12.820 -17.690  1.00 47.82  ? 471 HIS A N     1 
ATOM   3676  C CA    . HIS A 1 471 ? -29.404 -14.126 -17.719  1.00 44.52  ? 471 HIS A CA    1 
ATOM   3677  C C     . HIS A 1 471 ? -27.913 -13.897 -17.486  1.00 42.93  ? 471 HIS A C     1 
ATOM   3678  O O     . HIS A 1 471 ? -27.364 -12.857 -17.905  1.00 41.28  ? 471 HIS A O     1 
ATOM   3679  C CB    . HIS A 1 471 ? -29.791 -14.830 -19.050  1.00 52.42  ? 471 HIS A CB    1 
ATOM   3680  C CG    . HIS A 1 471 ? -29.177 -16.167 -19.321  1.00 55.95  ? 471 HIS A CG    1 
ATOM   3681  N ND1   . HIS A 1 471 ? -27.854 -16.330 -19.678  1.00 57.15  ? 471 HIS A ND1   1 
ATOM   3682  C CD2   . HIS A 1 471 ? -29.687 -17.413 -19.239  1.00 61.01  ? 471 HIS A CD2   1 
ATOM   3683  C CE1   . HIS A 1 471 ? -27.577 -17.631 -19.778  1.00 57.27  ? 471 HIS A CE1   1 
ATOM   3684  N NE2   . HIS A 1 471 ? -28.675 -18.309 -19.510  1.00 63.37  ? 471 HIS A NE2   1 
ATOM   3685  N N     . ILE A 1 472 ? -27.264 -14.879 -16.833  1.00 42.99  ? 472 ILE A N     1 
ATOM   3686  C CA    . ILE A 1 472 ? -25.835 -14.807 -16.525  1.00 42.91  ? 472 ILE A CA    1 
ATOM   3687  C C     . ILE A 1 472 ? -25.061 -14.398 -17.763  1.00 42.90  ? 472 ILE A C     1 
ATOM   3688  O O     . ILE A 1 472 ? -24.043 -13.717 -17.679  1.00 54.91  ? 472 ILE A O     1 
ATOM   3689  C CB    . ILE A 1 472 ? -25.252 -16.121 -15.973  1.00 45.32  ? 472 ILE A CB    1 
ATOM   3690  C CG1   . ILE A 1 472 ? -25.633 -17.312 -16.845  1.00 59.05  ? 472 ILE A CG1   1 
ATOM   3691  C CG2   . ILE A 1 472 ? -25.622 -16.361 -14.522  1.00 40.72  ? 472 ILE A CG2   1 
ATOM   3692  C CD1   . ILE A 1 472 ? -24.907 -18.590 -16.484  1.00 72.29  ? 472 ILE A CD1   1 
ATOM   3693  N N     . ARG A 1 473 ? -25.533 -14.858 -18.913  1.00 44.43  ? 473 ARG A N     1 
ATOM   3694  C CA    . ARG A 1 473 ? -24.788 -14.704 -20.140  1.00 44.67  ? 473 ARG A CA    1 
ATOM   3695  C C     . ARG A 1 473 ? -24.761 -13.229 -20.511  1.00 37.38  ? 473 ARG A C     1 
ATOM   3696  O O     . ARG A 1 473 ? -23.815 -12.799 -21.125  1.00 36.01  ? 473 ARG A O     1 
ATOM   3697  C CB    . ARG A 1 473 ? -25.409 -15.588 -21.231  1.00 56.06  ? 473 ARG A CB    1 
ATOM   3698  C CG    . ARG A 1 473 ? -24.840 -15.348 -22.620  1.00 68.87  ? 473 ARG A CG    1 
ATOM   3699  C CD    . ARG A 1 473 ? -25.404 -16.291 -23.670  1.00 79.64  ? 473 ARG A CD    1 
ATOM   3700  N NE    . ARG A 1 473 ? -24.860 -16.028 -25.003  1.00 78.27  ? 473 ARG A NE    1 
ATOM   3701  C CZ    . ARG A 1 473 ? -23.599 -16.249 -25.365  1.00 71.08  ? 473 ARG A CZ    1 
ATOM   3702  N NH1   . ARG A 1 473 ? -22.721 -16.710 -24.490  1.00 76.54  ? 473 ARG A NH1   1 
ATOM   3703  N NH2   . ARG A 1 473 ? -23.225 -16.027 -26.613  1.00 66.08  ? 473 ARG A NH2   1 
ATOM   3704  N N     . TYR A 1 474 ? -25.791 -12.454 -20.150  1.00 43.25  ? 474 TYR A N     1 
ATOM   3705  C CA    . TYR A 1 474 ? -25.941 -11.101 -20.678  1.00 46.17  ? 474 TYR A CA    1 
ATOM   3706  C C     . TYR A 1 474 ? -25.612 -10.040 -19.626  1.00 41.42  ? 474 TYR A C     1 
ATOM   3707  O O     . TYR A 1 474 ? -25.752 -8.858  -19.907  1.00 41.88  ? 474 TYR A O     1 
ATOM   3708  C CB    . TYR A 1 474 ? -27.348 -10.910 -21.255  1.00 47.88  ? 474 TYR A CB    1 
ATOM   3709  C CG    . TYR A 1 474 ? -27.663 -11.865 -22.379  1.00 52.37  ? 474 TYR A CG    1 
ATOM   3710  C CD1   . TYR A 1 474 ? -26.911 -11.872 -23.542  1.00 52.27  ? 474 TYR A CD1   1 
ATOM   3711  C CD2   . TYR A 1 474 ? -28.706 -12.771 -22.277  1.00 55.71  ? 474 TYR A CD2   1 
ATOM   3712  C CE1   . TYR A 1 474 ? -27.173 -12.768 -24.565  1.00 57.23  ? 474 TYR A CE1   1 
ATOM   3713  C CE2   . TYR A 1 474 ? -28.995 -13.663 -23.293  1.00 54.83  ? 474 TYR A CE2   1 
ATOM   3714  C CZ    . TYR A 1 474 ? -28.212 -13.677 -24.436  1.00 62.57  ? 474 TYR A CZ    1 
ATOM   3715  O OH    . TYR A 1 474 ? -28.499 -14.576 -25.449  1.00 63.69  ? 474 TYR A OH    1 
ATOM   3716  N N     . MET A 1 475 ? -25.144 -10.462 -18.445  1.00 36.43  ? 475 MET A N     1 
ATOM   3717  C CA    . MET A 1 475 ? -24.940 -9.566  -17.319  1.00 37.12  ? 475 MET A CA    1 
ATOM   3718  C C     . MET A 1 475 ? -24.053 -8.376  -17.673  1.00 40.06  ? 475 MET A C     1 
ATOM   3719  O O     . MET A 1 475 ? -24.419 -7.258  -17.322  1.00 45.89  ? 475 MET A O     1 
ATOM   3720  C CB    . MET A 1 475 ? -24.337 -10.311 -16.124  1.00 36.75  ? 475 MET A CB    1 
ATOM   3721  C CG    . MET A 1 475 ? -25.420 -10.945 -15.286  1.00 37.14  ? 475 MET A CG    1 
ATOM   3722  S SD    . MET A 1 475 ? -24.899 -12.158 -14.078  1.00 41.54  ? 475 MET A SD    1 
ATOM   3723  C CE    . MET A 1 475 ? -26.522 -12.640 -13.489  1.00 42.97  ? 475 MET A CE    1 
ATOM   3724  N N     . ASP A 1 476 ? -22.904 -8.598  -18.326  1.00 39.62  ? 476 ASP A N     1 
ATOM   3725  C CA    . ASP A 1 476 ? -22.025 -7.499  -18.716  1.00 45.71  ? 476 ASP A CA    1 
ATOM   3726  C C     . ASP A 1 476 ? -22.721 -6.543  -19.673  1.00 43.16  ? 476 ASP A C     1 
ATOM   3727  O O     . ASP A 1 476 ? -22.601 -5.325  -19.555  1.00 44.33  ? 476 ASP A O     1 
ATOM   3728  C CB    . ASP A 1 476 ? -20.741 -7.934  -19.429  1.00 45.47  ? 476 ASP A CB    1 
ATOM   3729  C CG    . ASP A 1 476 ? -19.673 -8.448  -18.485  1.00 55.97  ? 476 ASP A CG    1 
ATOM   3730  O OD1   . ASP A 1 476 ? -19.428 -7.775  -17.449  1.00 60.15  ? 476 ASP A OD1   1 
ATOM   3731  O OD2   . ASP A 1 476 ? -19.067 -9.488  -18.813  1.00 73.05  ? 476 ASP A OD2   1 
ATOM   3732  N N     . ARG A 1 477 ? -23.435 -7.122  -20.632  1.00 47.56  ? 477 ARG A N     1 
ATOM   3733  C CA    . ARG A 1 477 ? -24.073 -6.337  -21.668  1.00 47.03  ? 477 ARG A CA    1 
ATOM   3734  C C     . ARG A 1 477 ? -25.101 -5.408  -21.021  1.00 40.10  ? 477 ARG A C     1 
ATOM   3735  O O     . ARG A 1 477 ? -25.239 -4.255  -21.428  1.00 31.71  ? 477 ARG A O     1 
ATOM   3736  C CB    . ARG A 1 477 ? -24.681 -7.272  -22.723  1.00 47.49  ? 477 ARG A CB    1 
ATOM   3737  C CG    . ARG A 1 477 ? -25.558 -6.550  -23.738  1.00 56.83  ? 477 ARG A CG    1 
ATOM   3738  C CD    . ARG A 1 477 ? -24.791 -5.576  -24.630  1.00 62.87  ? 477 ARG A CD    1 
ATOM   3739  N NE    . ARG A 1 477 ? -25.668 -4.627  -25.303  1.00 58.60  ? 477 ARG A NE    1 
ATOM   3740  C CZ    . ARG A 1 477 ? -26.101 -3.489  -24.775  1.00 58.30  ? 477 ARG A CZ    1 
ATOM   3741  N NH1   . ARG A 1 477 ? -25.710 -3.118  -23.572  1.00 66.01  ? 477 ARG A NH1   1 
ATOM   3742  N NH2   . ARG A 1 477 ? -26.896 -2.695  -25.464  1.00 60.39  ? 477 ARG A NH2   1 
ATOM   3743  N N     . ILE A 1 478 ? -25.822 -5.922  -20.018  1.00 38.02  ? 478 ILE A N     1 
ATOM   3744  C CA    . ILE A 1 478 ? -26.909 -5.167  -19.416  1.00 39.13  ? 478 ILE A CA    1 
ATOM   3745  C C     . ILE A 1 478 ? -26.308 -4.083  -18.531  1.00 38.78  ? 478 ILE A C     1 
ATOM   3746  O O     . ILE A 1 478 ? -26.877 -2.989  -18.470  1.00 37.78  ? 478 ILE A O     1 
ATOM   3747  C CB    . ILE A 1 478 ? -27.907 -6.093  -18.687  1.00 39.29  ? 478 ILE A CB    1 
ATOM   3748  C CG1   . ILE A 1 478 ? -28.623 -7.007  -19.671  1.00 37.92  ? 478 ILE A CG1   1 
ATOM   3749  C CG2   . ILE A 1 478 ? -28.910 -5.317  -17.863  1.00 42.72  ? 478 ILE A CG2   1 
ATOM   3750  C CD1   . ILE A 1 478 ? -29.122 -6.243  -20.859  1.00 40.95  ? 478 ILE A CD1   1 
ATOM   3751  N N     . ALA A 1 479 ? -25.120 -4.358  -17.951  1.00 40.36  ? 479 ALA A N     1 
ATOM   3752  C CA    . ALA A 1 479 ? -24.402 -3.369  -17.148  1.00 40.89  ? 479 ALA A CA    1 
ATOM   3753  C C     . ALA A 1 479 ? -23.986 -2.186  -18.017  1.00 37.69  ? 479 ALA A C     1 
ATOM   3754  O O     . ALA A 1 479 ? -24.055 -1.032  -17.597  1.00 44.00  ? 479 ALA A O     1 
ATOM   3755  C CB    . ALA A 1 479 ? -23.199 -3.983  -16.468  1.00 44.64  ? 479 ALA A CB    1 
ATOM   3756  N N     . LYS A 1 480 ? -23.571 -2.470  -19.244  1.00 40.08  ? 480 LYS A N     1 
ATOM   3757  C CA    . LYS A 1 480 ? -23.042 -1.421  -20.101  1.00 45.18  ? 480 LYS A CA    1 
ATOM   3758  C C     . LYS A 1 480 ? -24.167 -0.500  -20.546  1.00 37.58  ? 480 LYS A C     1 
ATOM   3759  O O     . LYS A 1 480 ? -23.874 0.511   -21.147  1.00 35.18  ? 480 LYS A O     1 
ATOM   3760  C CB    . LYS A 1 480 ? -22.286 -1.986  -21.312  1.00 49.07  ? 480 LYS A CB    1 
ATOM   3761  C CG    . LYS A 1 480 ? -21.032 -2.804  -20.993  1.00 53.20  ? 480 LYS A CG    1 
ATOM   3762  C CD    . LYS A 1 480 ? -20.208 -3.136  -22.243  1.00 68.58  ? 480 LYS A CD    1 
ATOM   3763  C CE    . LYS A 1 480 ? -19.857 -4.602  -22.444  1.00 83.93  ? 480 LYS A CE    1 
ATOM   3764  N NZ    . LYS A 1 480 ? -18.713 -5.044  -21.608  1.00 87.36  ? 480 LYS A NZ    1 
ATOM   3765  N N     . THR A 1 481 ? -25.436 -0.808  -20.228  1.00 43.35  ? 481 THR A N     1 
ATOM   3766  C CA    . THR A 1 481 ? -26.535 0.076   -20.613  1.00 44.21  ? 481 THR A CA    1 
ATOM   3767  C C     . THR A 1 481 ? -26.619 1.254   -19.649  1.00 39.33  ? 481 THR A C     1 
ATOM   3768  O O     . THR A 1 481 ? -27.057 2.315   -20.061  1.00 50.61  ? 481 THR A O     1 
ATOM   3769  C CB    . THR A 1 481 ? -27.870 -0.666  -20.809  1.00 48.46  ? 481 THR A CB    1 
ATOM   3770  O OG1   . THR A 1 481 ? -28.334 -1.397  -19.698  1.00 42.42  ? 481 THR A OG1   1 
ATOM   3771  C CG2   . THR A 1 481 ? -27.781 -1.747  -21.858  1.00 65.07  ? 481 THR A CG2   1 
ATOM   3772  N N     . TYR A 1 482 ? -26.116 1.081   -18.425  1.00 39.60  ? 482 TYR A N     1 
ATOM   3773  C CA    . TYR A 1 482 ? -26.184 2.059   -17.350  1.00 41.33  ? 482 TYR A CA    1 
ATOM   3774  C C     . TYR A 1 482 ? -24.889 2.881   -17.294  1.00 44.91  ? 482 TYR A C     1 
ATOM   3775  O O     . TYR A 1 482 ? -24.194 2.906   -16.278  1.00 41.64  ? 482 TYR A O     1 
ATOM   3776  C CB    . TYR A 1 482 ? -26.477 1.290   -16.054  1.00 42.39  ? 482 TYR A CB    1 
ATOM   3777  C CG    . TYR A 1 482 ? -27.864 0.692   -16.043  1.00 40.31  ? 482 TYR A CG    1 
ATOM   3778  C CD1   . TYR A 1 482 ? -28.960 1.440   -15.642  1.00 34.95  ? 482 TYR A CD1   1 
ATOM   3779  C CD2   . TYR A 1 482 ? -28.103 -0.579  -16.560  1.00 37.56  ? 482 TYR A CD2   1 
ATOM   3780  C CE1   . TYR A 1 482 ? -30.253 0.926   -15.716  1.00 40.68  ? 482 TYR A CE1   1 
ATOM   3781  C CE2   . TYR A 1 482 ? -29.382 -1.112  -16.614  1.00 35.85  ? 482 TYR A CE2   1 
ATOM   3782  C CZ    . TYR A 1 482 ? -30.470 -0.365  -16.185  1.00 40.80  ? 482 TYR A CZ    1 
ATOM   3783  O OH    . TYR A 1 482 ? -31.767 -0.872  -16.244  1.00 37.87  ? 482 TYR A OH    1 
ATOM   3784  N N     . SER A 1 483 ? -24.626 3.632   -18.372  1.00 43.93  ? 483 SER A N     1 
ATOM   3785  C CA    . SER A 1 483 ? -23.285 4.098   -18.703  1.00 43.58  ? 483 SER A CA    1 
ATOM   3786  C C     . SER A 1 483 ? -23.070 5.606   -18.495  1.00 36.03  ? 483 SER A C     1 
ATOM   3787  O O     . SER A 1 483 ? -22.054 6.156   -18.921  1.00 39.73  ? 483 SER A O     1 
ATOM   3788  C CB    . SER A 1 483 ? -23.004 3.759   -20.155  1.00 41.94  ? 483 SER A CB    1 
ATOM   3789  O OG    . SER A 1 483 ? -23.824 4.553   -21.005  1.00 38.65  ? 483 SER A OG    1 
ATOM   3790  N N     . TRP A 1 484 ? -24.035 6.299   -17.910  1.00 34.60  ? 484 TRP A N     1 
ATOM   3791  C CA    . TRP A 1 484 ? -23.941 7.740   -17.777  1.00 32.93  ? 484 TRP A CA    1 
ATOM   3792  C C     . TRP A 1 484 ? -22.662 8.119   -17.031  1.00 36.78  ? 484 TRP A C     1 
ATOM   3793  O O     . TRP A 1 484 ? -22.340 7.487   -16.016  1.00 34.65  ? 484 TRP A O     1 
ATOM   3794  C CB    . TRP A 1 484 ? -25.152 8.276   -17.072  1.00 33.33  ? 484 TRP A CB    1 
ATOM   3795  C CG    . TRP A 1 484 ? -25.163 9.767   -16.910  1.00 39.98  ? 484 TRP A CG    1 
ATOM   3796  C CD1   . TRP A 1 484 ? -25.607 10.679  -17.817  1.00 36.77  ? 484 TRP A CD1   1 
ATOM   3797  C CD2   . TRP A 1 484 ? -24.765 10.521  -15.746  1.00 36.27  ? 484 TRP A CD2   1 
ATOM   3798  N NE1   . TRP A 1 484 ? -25.502 11.935  -17.297  1.00 35.09  ? 484 TRP A NE1   1 
ATOM   3799  C CE2   . TRP A 1 484 ? -24.975 11.877  -16.043  1.00 35.10  ? 484 TRP A CE2   1 
ATOM   3800  C CE3   . TRP A 1 484 ? -24.262 10.184  -14.489  1.00 35.81  ? 484 TRP A CE3   1 
ATOM   3801  C CZ2   . TRP A 1 484 ? -24.698 12.903  -15.140  1.00 37.29  ? 484 TRP A CZ2   1 
ATOM   3802  C CZ3   . TRP A 1 484 ? -23.996 11.195  -13.588  1.00 40.71  ? 484 TRP A CZ3   1 
ATOM   3803  C CH2   . TRP A 1 484 ? -24.211 12.539  -13.911  1.00 37.01  ? 484 TRP A CH2   1 
ATOM   3804  N N     . ASN A 1 485 ? -21.937 9.100   -17.607  1.00 32.19  ? 485 ASN A N     1 
ATOM   3805  C CA    . ASN A 1 485 ? -20.713 9.662   -17.047  1.00 38.64  ? 485 ASN A CA    1 
ATOM   3806  C C     . ASN A 1 485 ? -19.622 8.605   -17.014  1.00 35.02  ? 485 ASN A C     1 
ATOM   3807  O O     . ASN A 1 485 ? -19.151 8.229   -15.946  1.00 34.91  ? 485 ASN A O     1 
ATOM   3808  C CB    . ASN A 1 485 ? -20.914 10.278  -15.658  1.00 40.00  ? 485 ASN A CB    1 
ATOM   3809  C CG    . ASN A 1 485 ? -19.660 10.993  -15.196  1.00 42.78  ? 485 ASN A CG    1 
ATOM   3810  O OD1   . ASN A 1 485 ? -18.886 11.472  -16.020  1.00 44.52  ? 485 ASN A OD1   1 
ATOM   3811  N ND2   . ASN A 1 485 ? -19.450 11.075  -13.892  1.00 41.64  ? 485 ASN A ND2   1 
ATOM   3812  N N     . ASP A 1 486 ? -19.305 8.087   -18.202  1.00 40.41  ? 486 ASP A N     1 
ATOM   3813  C CA    . ASP A 1 486 ? -18.332 7.026   -18.395  1.00 39.39  ? 486 ASP A CA    1 
ATOM   3814  C C     . ASP A 1 486 ? -18.457 5.946   -17.316  1.00 40.54  ? 486 ASP A C     1 
ATOM   3815  O O     . ASP A 1 486 ? -17.455 5.542   -16.726  1.00 38.92  ? 486 ASP A O     1 
ATOM   3816  C CB    . ASP A 1 486 ? -16.917 7.599   -18.462  1.00 42.80  ? 486 ASP A CB    1 
ATOM   3817  C CG    . ASP A 1 486 ? -15.871 6.600   -18.939  1.00 48.74  ? 486 ASP A CG    1 
ATOM   3818  O OD1   . ASP A 1 486 ? -16.180 5.806   -19.865  1.00 48.72  ? 486 ASP A OD1   1 
ATOM   3819  O OD2   . ASP A 1 486 ? -14.753 6.626   -18.389  1.00 46.95  ? 486 ASP A OD2   1 
ATOM   3820  N N     . ASN A 1 487 ? -19.676 5.427   -17.106  1.00 37.09  ? 487 ASN A N     1 
ATOM   3821  C CA    . ASN A 1 487 ? -19.886 4.240   -16.286  1.00 37.08  ? 487 ASN A CA    1 
ATOM   3822  C C     . ASN A 1 487 ? -19.595 4.566   -14.818  1.00 40.55  ? 487 ASN A C     1 
ATOM   3823  O O     . ASN A 1 487 ? -18.973 3.776   -14.094  1.00 43.20  ? 487 ASN A O     1 
ATOM   3824  C CB    . ASN A 1 487 ? -19.108 3.012   -16.781  1.00 34.72  ? 487 ASN A CB    1 
ATOM   3825  C CG    . ASN A 1 487 ? -19.449 2.621   -18.208  1.00 42.09  ? 487 ASN A CG    1 
ATOM   3826  O OD1   . ASN A 1 487 ? -18.636 2.779   -19.121  1.00 41.54  ? 487 ASN A OD1   1 
ATOM   3827  N ND2   . ASN A 1 487 ? -20.666 2.145   -18.427  1.00 42.57  ? 487 ASN A ND2   1 
ATOM   3828  N N     . ALA A 1 488 ? -20.103 5.712   -14.357  1.00 36.70  ? 488 ALA A N     1 
ATOM   3829  C CA    . ALA A 1 488 ? -19.717 6.205   -13.042  1.00 36.77  ? 488 ALA A CA    1 
ATOM   3830  C C     . ALA A 1 488 ? -20.288 5.292   -11.972  1.00 36.53  ? 488 ALA A C     1 
ATOM   3831  O O     . ALA A 1 488 ? -19.623 5.022   -10.975  1.00 37.62  ? 488 ALA A O     1 
ATOM   3832  C CB    . ALA A 1 488 ? -20.136 7.635   -12.833  1.00 35.32  ? 488 ALA A CB    1 
ATOM   3833  N N     . LEU A 1 489 ? -21.467 4.730   -12.254  1.00 40.72  ? 489 LEU A N     1 
ATOM   3834  C CA    . LEU A 1 489 ? -22.144 3.908   -11.264  1.00 40.95  ? 489 LEU A CA    1 
ATOM   3835  C C     . LEU A 1 489 ? -21.382 2.607   -11.023  1.00 38.28  ? 489 LEU A C     1 
ATOM   3836  O O     . LEU A 1 489 ? -21.100 2.244   -9.882   1.00 40.06  ? 489 LEU A O     1 
ATOM   3837  C CB    . LEU A 1 489 ? -23.595 3.672   -11.698  1.00 39.08  ? 489 LEU A CB    1 
ATOM   3838  C CG    . LEU A 1 489 ? -24.415 2.767   -10.792  1.00 35.90  ? 489 LEU A CG    1 
ATOM   3839  C CD1   . LEU A 1 489 ? -24.392 3.255   -9.357   1.00 36.24  ? 489 LEU A CD1   1 
ATOM   3840  C CD2   . LEU A 1 489 ? -25.844 2.686   -11.292  1.00 39.64  ? 489 LEU A CD2   1 
ATOM   3841  N N     . TRP A 1 490 ? -21.061 1.898   -12.100  1.00 37.42  ? 490 TRP A N     1 
ATOM   3842  C CA    . TRP A 1 490 ? -20.336 0.645   -11.967  1.00 38.15  ? 490 TRP A CA    1 
ATOM   3843  C C     . TRP A 1 490 ? -18.950 0.875   -11.381  1.00 34.92  ? 490 TRP A C     1 
ATOM   3844  O O     . TRP A 1 490 ? -18.430 -0.037  -10.748  1.00 35.46  ? 490 TRP A O     1 
ATOM   3845  C CB    . TRP A 1 490 ? -20.256 -0.145  -13.296  1.00 36.88  ? 490 TRP A CB    1 
ATOM   3846  C CG    . TRP A 1 490 ? -21.181 -1.324  -13.287  1.00 36.02  ? 490 TRP A CG    1 
ATOM   3847  C CD1   . TRP A 1 490 ? -20.836 -2.642  -13.289  1.00 32.82  ? 490 TRP A CD1   1 
ATOM   3848  C CD2   . TRP A 1 490 ? -22.616 -1.284  -13.177  1.00 34.31  ? 490 TRP A CD2   1 
ATOM   3849  N NE1   . TRP A 1 490 ? -21.958 -3.423  -13.202  1.00 34.13  ? 490 TRP A NE1   1 
ATOM   3850  C CE2   . TRP A 1 490 ? -23.063 -2.618  -13.135  1.00 33.92  ? 490 TRP A CE2   1 
ATOM   3851  C CE3   . TRP A 1 490 ? -23.554 -0.259  -13.077  1.00 32.42  ? 490 TRP A CE3   1 
ATOM   3852  C CZ2   . TRP A 1 490 ? -24.411 -2.948  -12.992  1.00 32.34  ? 490 TRP A CZ2   1 
ATOM   3853  C CZ3   . TRP A 1 490 ? -24.889 -0.589  -12.992  1.00 32.64  ? 490 TRP A CZ3   1 
ATOM   3854  C CH2   . TRP A 1 490 ? -25.306 -1.913  -12.897  1.00 29.13  ? 490 TRP A CH2   1 
ATOM   3855  N N     . LYS A 1 491 ? -18.346 2.046   -11.626  1.00 35.43  ? 491 LYS A N     1 
ATOM   3856  C CA    . LYS A 1 491 ? -17.046 2.329   -11.025  1.00 40.10  ? 491 LYS A CA    1 
ATOM   3857  C C     . LYS A 1 491 ? -17.180 2.368   -9.506   1.00 41.58  ? 491 LYS A C     1 
ATOM   3858  O O     . LYS A 1 491 ? -16.292 1.891   -8.810   1.00 37.98  ? 491 LYS A O     1 
ATOM   3859  C CB    . LYS A 1 491 ? -16.448 3.642   -11.531  1.00 40.89  ? 491 LYS A CB    1 
ATOM   3860  C CG    . LYS A 1 491 ? -15.806 3.553   -12.911  1.00 42.12  ? 491 LYS A CG    1 
ATOM   3861  C CD    . LYS A 1 491 ? -15.472 4.904   -13.468  1.00 44.31  ? 491 LYS A CD    1 
ATOM   3862  C CE    . LYS A 1 491 ? -14.947 4.811   -14.888  1.00 49.97  ? 491 LYS A CE    1 
ATOM   3863  N NZ    . LYS A 1 491 ? -14.926 6.150   -15.533  1.00 49.64  ? 491 LYS A NZ    1 
ATOM   3864  N N     . MET A 1 492 ? -18.306 2.913   -9.011   1.00 41.35  ? 492 MET A N     1 
ATOM   3865  C CA    . MET A 1 492 ? -18.555 2.926   -7.584   1.00 43.18  ? 492 MET A CA    1 
ATOM   3866  C C     . MET A 1 492 ? -18.768 1.494   -7.083   1.00 44.84  ? 492 MET A C     1 
ATOM   3867  O O     . MET A 1 492 ? -18.139 1.098   -6.092   1.00 45.30  ? 492 MET A O     1 
ATOM   3868  C CB    . MET A 1 492 ? -19.749 3.810   -7.221   1.00 40.91  ? 492 MET A CB    1 
ATOM   3869  C CG    . MET A 1 492 ? -20.016 3.860   -5.729   1.00 38.91  ? 492 MET A CG    1 
ATOM   3870  S SD    . MET A 1 492 ? -21.550 4.714   -5.367   1.00 45.50  ? 492 MET A SD    1 
ATOM   3871  C CE    . MET A 1 492 ? -22.722 3.411   -5.709   1.00 42.16  ? 492 MET A CE    1 
ATOM   3872  N N     . HIS A 1 493 ? -19.608 0.708   -7.779   1.00 41.15  ? 493 HIS A N     1 
ATOM   3873  C CA    . HIS A 1 493 ? -19.705 -0.718  -7.498   1.00 41.16  ? 493 HIS A CA    1 
ATOM   3874  C C     . HIS A 1 493 ? -18.317 -1.377  -7.429   1.00 42.09  ? 493 HIS A C     1 
ATOM   3875  O O     . HIS A 1 493 ? -18.015 -2.130  -6.498   1.00 42.37  ? 493 HIS A O     1 
ATOM   3876  C CB    . HIS A 1 493 ? -20.603 -1.432  -8.500   1.00 38.76  ? 493 HIS A CB    1 
ATOM   3877  C CG    . HIS A 1 493 ? -22.020 -1.033  -8.482   1.00 38.28  ? 493 HIS A CG    1 
ATOM   3878  N ND1   . HIS A 1 493 ? -22.635 -0.478  -7.400   1.00 40.85  ? 493 HIS A ND1   1 
ATOM   3879  C CD2   . HIS A 1 493 ? -22.981 -1.140  -9.425   1.00 44.39  ? 493 HIS A CD2   1 
ATOM   3880  C CE1   . HIS A 1 493 ? -23.919 -0.266  -7.675   1.00 40.40  ? 493 HIS A CE1   1 
ATOM   3881  N NE2   . HIS A 1 493 ? -24.153 -0.634  -8.907   1.00 36.68  ? 493 HIS A NE2   1 
ATOM   3882  N N     . GLU A 1 494 ? -17.445 -1.085  -8.392   1.00 48.24  ? 494 GLU A N     1 
ATOM   3883  C CA    . GLU A 1 494 ? -16.098 -1.656  -8.388   1.00 48.65  ? 494 GLU A CA    1 
ATOM   3884  C C     . GLU A 1 494 ? -15.336 -1.207  -7.130   1.00 47.92  ? 494 GLU A C     1 
ATOM   3885  O O     . GLU A 1 494 ? -14.628 -1.995  -6.486   1.00 42.44  ? 494 GLU A O     1 
ATOM   3886  C CB    . GLU A 1 494 ? -15.375 -1.270  -9.678   1.00 53.38  ? 494 GLU A CB    1 
ATOM   3887  C CG    . GLU A 1 494 ? -15.983 -1.821  -10.978  1.00 59.93  ? 494 GLU A CG    1 
ATOM   3888  C CD    . GLU A 1 494 ? -15.909 -3.337  -11.177  1.00 78.28  ? 494 GLU A CD    1 
ATOM   3889  O OE1   . GLU A 1 494 ? -15.297 -4.060  -10.322  1.00 76.66  ? 494 GLU A OE1   1 
ATOM   3890  O OE2   . GLU A 1 494 ? -16.467 -3.824  -12.198  1.00 88.48  ? 494 GLU A OE2   1 
ATOM   3891  N N     . THR A 1 495 ? -15.514 0.059   -6.721   1.00 45.94  ? 495 THR A N     1 
ATOM   3892  C CA    . THR A 1 495 ? -14.855 0.546   -5.519   1.00 42.29  ? 495 THR A CA    1 
ATOM   3893  C C     . THR A 1 495 ? -15.288 -0.223  -4.264   1.00 41.61  ? 495 THR A C     1 
ATOM   3894  O O     . THR A 1 495 ? -14.465 -0.597  -3.439   1.00 42.11  ? 495 THR A O     1 
ATOM   3895  C CB    . THR A 1 495 ? -15.133 2.030   -5.307   1.00 46.35  ? 495 THR A CB    1 
ATOM   3896  O OG1   . THR A 1 495 ? -14.452 2.768   -6.323   1.00 47.59  ? 495 THR A OG1   1 
ATOM   3897  C CG2   . THR A 1 495 ? -14.727 2.494   -3.920   1.00 44.50  ? 495 THR A CG2   1 
ATOM   3898  N N     . ILE A 1 496 ? -16.590 -0.466  -4.109   1.00 38.95  ? 496 ILE A N     1 
ATOM   3899  C CA    . ILE A 1 496 ? -17.107 -1.163  -2.941   1.00 34.52  ? 496 ILE A CA    1 
ATOM   3900  C C     . ILE A 1 496 ? -16.701 -2.630  -2.974   1.00 39.60  ? 496 ILE A C     1 
ATOM   3901  O O     . ILE A 1 496 ? -16.400 -3.219  -1.932   1.00 42.83  ? 496 ILE A O     1 
ATOM   3902  C CB    . ILE A 1 496 ? -18.630 -1.011  -2.926   1.00 33.88  ? 496 ILE A CB    1 
ATOM   3903  C CG1   . ILE A 1 496 ? -19.006 0.459   -2.717   1.00 33.58  ? 496 ILE A CG1   1 
ATOM   3904  C CG2   . ILE A 1 496 ? -19.277 -1.968  -1.936   1.00 32.45  ? 496 ILE A CG2   1 
ATOM   3905  C CD1   . ILE A 1 496 ? -20.492 0.691   -2.752   1.00 39.52  ? 496 ILE A CD1   1 
ATOM   3906  N N     . LYS A 1 497 ? -16.732 -3.207  -4.186   1.00 39.70  ? 497 LYS A N     1 
ATOM   3907  C CA    . LYS A 1 497 ? -16.288 -4.568  -4.442   1.00 40.55  ? 497 LYS A CA    1 
ATOM   3908  C C     . LYS A 1 497 ? -14.867 -4.835  -3.960   1.00 37.43  ? 497 LYS A C     1 
ATOM   3909  O O     . LYS A 1 497 ? -14.609 -5.876  -3.386   1.00 41.94  ? 497 LYS A O     1 
ATOM   3910  C CB    . LYS A 1 497 ? -16.297 -4.852  -5.944   1.00 39.25  ? 497 LYS A CB    1 
ATOM   3911  C CG    . LYS A 1 497 ? -15.952 -6.274  -6.304   1.00 37.60  ? 497 LYS A CG    1 
ATOM   3912  C CD    . LYS A 1 497 ? -16.759 -7.329  -5.591   1.00 38.25  ? 497 LYS A CD    1 
ATOM   3913  C CE    . LYS A 1 497 ? -16.664 -8.631  -6.364   1.00 42.87  ? 497 LYS A CE    1 
ATOM   3914  N NZ    . LYS A 1 497 ? -16.963 -9.794  -5.508   1.00 48.52  ? 497 LYS A NZ    1 
ATOM   3915  N N     . ASP A 1 498 ? -13.937 -3.944  -4.285   1.00 38.44  ? 498 ASP A N     1 
ATOM   3916  C CA    . ASP A 1 498 ? -12.536 -4.125  -3.932   1.00 39.58  ? 498 ASP A CA    1 
ATOM   3917  C C     . ASP A 1 498 ? -12.330 -3.937  -2.435   1.00 39.14  ? 498 ASP A C     1 
ATOM   3918  O O     . ASP A 1 498 ? -11.331 -4.379  -1.916   1.00 48.18  ? 498 ASP A O     1 
ATOM   3919  C CB    . ASP A 1 498 ? -11.645 -3.136  -4.701   1.00 38.49  ? 498 ASP A CB    1 
ATOM   3920  C CG    . ASP A 1 498 ? -11.606 -3.367  -6.211   1.00 40.04  ? 498 ASP A CG    1 
ATOM   3921  O OD1   . ASP A 1 498 ? -11.962 -4.476  -6.667   1.00 43.39  ? 498 ASP A OD1   1 
ATOM   3922  O OD2   . ASP A 1 498 ? -11.248 -2.430  -6.932   1.00 44.83  ? 498 ASP A OD2   1 
ATOM   3923  N N     . ALA A 1 499 ? -13.229 -3.206  -1.767   1.00 41.90  ? 499 ALA A N     1 
ATOM   3924  C CA    . ALA A 1 499 ? -13.137 -2.972  -0.337   1.00 40.45  ? 499 ALA A CA    1 
ATOM   3925  C C     . ALA A 1 499 ? -13.687 -4.163  0.423    1.00 37.01  ? 499 ALA A C     1 
ATOM   3926  O O     . ALA A 1 499 ? -13.142 -4.519  1.434    1.00 44.96  ? 499 ALA A O     1 
ATOM   3927  C CB    . ALA A 1 499 ? -13.894 -1.730  0.039    1.00 39.89  ? 499 ALA A CB    1 
ATOM   3928  N N     . LEU A 1 500 ? -14.816 -4.711  -0.010   1.00 41.03  ? 500 LEU A N     1 
ATOM   3929  C CA    . LEU A 1 500 ? -15.398 -5.850  0.679    1.00 46.69  ? 500 LEU A CA    1 
ATOM   3930  C C     . LEU A 1 500 ? -14.743 -7.154  0.239    1.00 48.23  ? 500 LEU A C     1 
ATOM   3931  O O     . LEU A 1 500 ? -14.721 -8.088  1.032    1.00 45.20  ? 500 LEU A O     1 
ATOM   3932  C CB    . LEU A 1 500 ? -16.899 -5.928  0.403    1.00 47.23  ? 500 LEU A CB    1 
ATOM   3933  C CG    . LEU A 1 500 ? -17.718 -4.780  0.976    1.00 50.61  ? 500 LEU A CG    1 
ATOM   3934  C CD1   . LEU A 1 500 ? -19.175 -4.884  0.550    1.00 51.29  ? 500 LEU A CD1   1 
ATOM   3935  C CD2   . LEU A 1 500 ? -17.601 -4.765  2.490    1.00 50.05  ? 500 LEU A CD2   1 
ATOM   3936  N N     . ASP A 1 501 ? -14.265 -7.221  -1.020   1.00 51.19  ? 501 ASP A N     1 
ATOM   3937  C CA    . ASP A 1 501 ? -13.752 -8.460  -1.598   1.00 46.74  ? 501 ASP A CA    1 
ATOM   3938  C C     . ASP A 1 501 ? -12.400 -8.265  -2.281   1.00 41.24  ? 501 ASP A C     1 
ATOM   3939  O O     . ASP A 1 501 ? -12.260 -8.544  -3.459   1.00 40.93  ? 501 ASP A O     1 
ATOM   3940  C CB    . ASP A 1 501 ? -14.741 -9.041  -2.599   1.00 40.92  ? 501 ASP A CB    1 
ATOM   3941  C CG    . ASP A 1 501 ? -14.467 -10.490 -2.930   1.00 43.88  ? 501 ASP A CG    1 
ATOM   3942  O OD1   . ASP A 1 501 ? -13.443 -11.035 -2.433   1.00 45.62  ? 501 ASP A OD1   1 
ATOM   3943  O OD2   . ASP A 1 501 ? -15.277 -11.054 -3.688   1.00 42.81  ? 501 ASP A OD2   1 
ATOM   3944  N N     . PRO A 1 502 ? -11.328 -7.892  -1.558   1.00 45.08  ? 502 PRO A N     1 
ATOM   3945  C CA    . PRO A 1 502 ? -10.073 -7.529  -2.211   1.00 46.26  ? 502 PRO A CA    1 
ATOM   3946  C C     . PRO A 1 502 ? -9.480  -8.650  -3.066   1.00 45.70  ? 502 PRO A C     1 
ATOM   3947  O O     . PRO A 1 502 ? -8.781  -8.347  -4.019   1.00 54.15  ? 502 PRO A O     1 
ATOM   3948  C CB    . PRO A 1 502 ? -9.092  -7.204  -1.074   1.00 42.83  ? 502 PRO A CB    1 
ATOM   3949  C CG    . PRO A 1 502 ? -9.737  -7.657  0.199    1.00 40.38  ? 502 PRO A CG    1 
ATOM   3950  C CD    . PRO A 1 502 ? -11.220 -7.885  -0.090   1.00 46.84  ? 502 PRO A CD    1 
ATOM   3951  N N     . ASN A 1 503 ? -9.756  -9.921  -2.730   1.00 43.42  ? 503 ASN A N     1 
ATOM   3952  C CA    . ASN A 1 503 ? -9.209  -11.058 -3.462   1.00 43.70  ? 503 ASN A CA    1 
ATOM   3953  C C     . ASN A 1 503 ? -10.183 -11.545 -4.525   1.00 45.29  ? 503 ASN A C     1 
ATOM   3954  O O     . ASN A 1 503 ? -9.873  -12.478 -5.249   1.00 50.82  ? 503 ASN A O     1 
ATOM   3955  C CB    . ASN A 1 503 ? -8.797  -12.225 -2.558   1.00 41.19  ? 503 ASN A CB    1 
ATOM   3956  C CG    . ASN A 1 503 ? -7.751  -11.828 -1.532   1.00 44.96  ? 503 ASN A CG    1 
ATOM   3957  O OD1   . ASN A 1 503 ? -6.746  -11.195 -1.858   1.00 42.26  ? 503 ASN A OD1   1 
ATOM   3958  N ND2   . ASN A 1 503 ? -8.025  -12.120 -0.271   1.00 41.56  ? 503 ASN A ND2   1 
ATOM   3959  N N     . GLY A 1 504 ? -11.372 -10.946 -4.579   1.00 52.64  ? 504 GLY A N     1 
ATOM   3960  C CA    . GLY A 1 504 ? -12.308 -11.180 -5.663   1.00 44.05  ? 504 GLY A CA    1 
ATOM   3961  C C     . GLY A 1 504 ? -12.740 -12.629 -5.726   1.00 38.47  ? 504 GLY A C     1 
ATOM   3962  O O     . GLY A 1 504 ? -12.668 -13.242 -6.773   1.00 40.95  ? 504 GLY A O     1 
ATOM   3963  N N     . ILE A 1 505 ? -13.190 -13.188 -4.607   1.00 40.51  ? 505 ILE A N     1 
ATOM   3964  C CA    . ILE A 1 505 ? -13.472 -14.616 -4.617   1.00 45.93  ? 505 ILE A CA    1 
ATOM   3965  C C     . ILE A 1 505 ? -14.976 -14.882 -4.564   1.00 46.94  ? 505 ILE A C     1 
ATOM   3966  O O     . ILE A 1 505 ? -15.356 -16.035 -4.389   1.00 49.62  ? 505 ILE A O     1 
ATOM   3967  C CB    . ILE A 1 505 ? -12.679 -15.335 -3.505   1.00 56.01  ? 505 ILE A CB    1 
ATOM   3968  C CG1   . ILE A 1 505 ? -13.015 -14.836 -2.097   1.00 54.51  ? 505 ILE A CG1   1 
ATOM   3969  C CG2   . ILE A 1 505 ? -11.185 -15.223 -3.774   1.00 55.07  ? 505 ILE A CG2   1 
ATOM   3970  C CD1   . ILE A 1 505 ? -14.360 -15.288 -1.625   1.00 58.49  ? 505 ILE A CD1   1 
ATOM   3971  N N     . LEU A 1 506 ? -15.809 -13.835 -4.753   1.00 48.29  ? 506 LEU A N     1 
ATOM   3972  C CA    . LEU A 1 506 ? -17.269 -13.950 -4.780   1.00 48.34  ? 506 LEU A CA    1 
ATOM   3973  C C     . LEU A 1 506 ? -17.877 -13.557 -6.136   1.00 45.67  ? 506 LEU A C     1 
ATOM   3974  O O     . LEU A 1 506 ? -17.828 -12.398 -6.568   1.00 37.69  ? 506 LEU A O     1 
ATOM   3975  C CB    . LEU A 1 506 ? -17.895 -13.093 -3.676   1.00 52.36  ? 506 LEU A CB    1 
ATOM   3976  C CG    . LEU A 1 506 ? -18.386 -13.810 -2.418   1.00 63.26  ? 506 LEU A CG    1 
ATOM   3977  C CD1   . LEU A 1 506 ? -19.437 -12.967 -1.711   1.00 65.69  ? 506 LEU A CD1   1 
ATOM   3978  C CD2   . LEU A 1 506 ? -18.957 -15.182 -2.726   1.00 68.04  ? 506 LEU A CD2   1 
ATOM   3979  N N     . ALA A 1 507 ? -18.504 -14.562 -6.769   1.00 45.39  ? 507 ALA A N     1 
ATOM   3980  C CA    . ALA A 1 507 ? -19.249 -14.440 -8.012   1.00 42.33  ? 507 ALA A CA    1 
ATOM   3981  C C     . ALA A 1 507 ? -18.676 -13.340 -8.900   1.00 40.63  ? 507 ALA A C     1 
ATOM   3982  O O     . ALA A 1 507 ? -19.347 -12.350 -9.202   1.00 40.49  ? 507 ALA A O     1 
ATOM   3983  C CB    . ALA A 1 507 ? -20.720 -14.231 -7.730   1.00 45.79  ? 507 ALA A CB    1 
ATOM   3984  N N     . PRO A 1 508 ? -17.428 -13.514 -9.379   1.00 42.27  ? 508 PRO A N     1 
ATOM   3985  C CA    . PRO A 1 508 ? -16.848 -12.596 -10.355  1.00 47.93  ? 508 PRO A CA    1 
ATOM   3986  C C     . PRO A 1 508 ? -17.747 -12.483 -11.577  1.00 47.88  ? 508 PRO A C     1 
ATOM   3987  O O     . PRO A 1 508 ? -18.075 -13.498 -12.198  1.00 58.21  ? 508 PRO A O     1 
ATOM   3988  C CB    . PRO A 1 508 ? -15.509 -13.260 -10.711  1.00 48.57  ? 508 PRO A CB    1 
ATOM   3989  C CG    . PRO A 1 508 ? -15.183 -14.058 -9.463   1.00 46.48  ? 508 PRO A CG    1 
ATOM   3990  C CD    . PRO A 1 508 ? -16.517 -14.624 -9.044   1.00 44.02  ? 508 PRO A CD    1 
ATOM   3991  N N     . GLY A 1 509 ? -18.181 -11.259 -11.887  1.00 37.40  ? 509 GLY A N     1 
ATOM   3992  C CA    . GLY A 1 509 ? -19.019 -11.072 -13.057  1.00 36.23  ? 509 GLY A CA    1 
ATOM   3993  C C     . GLY A 1 509 ? -20.524 -10.970 -12.795  1.00 34.23  ? 509 GLY A C     1 
ATOM   3994  O O     . GLY A 1 509 ? -21.253 -10.602 -13.699  1.00 42.89  ? 509 GLY A O     1 
ATOM   3995  N N     . LYS A 1 510 ? -21.020 -11.278 -11.603  1.00 32.27  ? 510 LYS A N     1 
ATOM   3996  C CA    . LYS A 1 510 ? -22.421 -11.021 -11.295  1.00 38.41  ? 510 LYS A CA    1 
ATOM   3997  C C     . LYS A 1 510 ? -22.708 -9.530  -11.509  1.00 40.24  ? 510 LYS A C     1 
ATOM   3998  O O     . LYS A 1 510 ? -21.935 -8.673  -11.091  1.00 38.65  ? 510 LYS A O     1 
ATOM   3999  C CB    . LYS A 1 510 ? -22.744 -11.498 -9.865   1.00 46.79  ? 510 LYS A CB    1 
ATOM   4000  C CG    . LYS A 1 510 ? -24.175 -11.283 -9.357   1.00 50.84  ? 510 LYS A CG    1 
ATOM   4001  C CD    . LYS A 1 510 ? -25.236 -12.165 -9.991   1.00 53.92  ? 510 LYS A CD    1 
ATOM   4002  C CE    . LYS A 1 510 ? -26.663 -11.925 -9.531   1.00 54.77  ? 510 LYS A CE    1 
ATOM   4003  N NZ    . LYS A 1 510 ? -27.492 -11.218 -10.532  1.00 58.83  ? 510 LYS A NZ    1 
ATOM   4004  N N     . SER A 1 511 ? -23.788 -9.230  -12.247  1.00 43.09  ? 511 SER A N     1 
ATOM   4005  C CA    . SER A 1 511 ? -24.219 -7.864  -12.535  1.00 42.89  ? 511 SER A CA    1 
ATOM   4006  C C     . SER A 1 511 ? -23.112 -7.044  -13.195  1.00 44.33  ? 511 SER A C     1 
ATOM   4007  O O     . SER A 1 511 ? -23.168 -5.812  -13.232  1.00 40.16  ? 511 SER A O     1 
ATOM   4008  C CB    . SER A 1 511 ? -24.742 -7.185  -11.292  1.00 44.75  ? 511 SER A CB    1 
ATOM   4009  O OG    . SER A 1 511 ? -25.733 -7.988  -10.657  1.00 43.24  ? 511 SER A OG    1 
ATOM   4010  N N     . GLY A 1 512 ? -22.123 -7.749  -13.750  1.00 39.32  ? 512 GLY A N     1 
ATOM   4011  C CA    . GLY A 1 512 ? -21.050 -7.112  -14.475  1.00 41.83  ? 512 GLY A CA    1 
ATOM   4012  C C     . GLY A 1 512 ? -20.061 -6.382  -13.577  1.00 41.38  ? 512 GLY A C     1 
ATOM   4013  O O     . GLY A 1 512 ? -19.471 -5.403  -14.038  1.00 42.81  ? 512 GLY A O     1 
ATOM   4014  N N     . ILE A 1 513 ? -19.874 -6.906  -12.350  1.00 43.50  ? 513 ILE A N     1 
ATOM   4015  C CA    . ILE A 1 513 ? -18.902 -6.430  -11.366  1.00 42.33  ? 513 ILE A CA    1 
ATOM   4016  C C     . ILE A 1 513 ? -17.764 -7.450  -11.230  1.00 41.98  ? 513 ILE A C     1 
ATOM   4017  O O     . ILE A 1 513 ? -18.013 -8.596  -10.891  1.00 42.28  ? 513 ILE A O     1 
ATOM   4018  C CB    . ILE A 1 513 ? -19.650 -6.247  -10.029  1.00 40.12  ? 513 ILE A CB    1 
ATOM   4019  C CG1   . ILE A 1 513 ? -20.913 -5.405  -10.210  1.00 43.02  ? 513 ILE A CG1   1 
ATOM   4020  C CG2   . ILE A 1 513 ? -18.755 -5.678  -8.955   1.00 37.36  ? 513 ILE A CG2   1 
ATOM   4021  C CD1   . ILE A 1 513 ? -21.867 -5.442  -9.018   1.00 42.86  ? 513 ILE A CD1   1 
ATOM   4022  N N     . TRP A 1 514 ? -16.487 -7.068  -11.392  1.00 50.00  ? 514 TRP A N     1 
ATOM   4023  C CA    . TRP A 1 514 ? -15.456 -8.105  -11.535  1.00 51.25  ? 514 TRP A CA    1 
ATOM   4024  C C     . TRP A 1 514 ? -14.470 -8.236  -10.342  1.00 61.74  ? 514 TRP A C     1 
ATOM   4025  O O     . TRP A 1 514 ? -14.202 -9.386  -9.754   1.00 52.78  ? 514 TRP A O     1 
ATOM   4026  C CB    . TRP A 1 514 ? -14.811 -7.858  -12.905  1.00 50.57  ? 514 TRP A CB    1 
ATOM   4027  C CG    . TRP A 1 514 ? -15.644 -8.443  -14.016  1.00 48.69  ? 514 TRP A CG    1 
ATOM   4028  C CD1   . TRP A 1 514 ? -16.579 -7.820  -14.791  1.00 47.01  ? 514 TRP A CD1   1 
ATOM   4029  C CD2   . TRP A 1 514 ? -15.671 -9.826  -14.415  1.00 46.50  ? 514 TRP A CD2   1 
ATOM   4030  N NE1   . TRP A 1 514 ? -17.153 -8.707  -15.663  1.00 48.13  ? 514 TRP A NE1   1 
ATOM   4031  C CE2   . TRP A 1 514 ? -16.594 -9.942  -15.474  1.00 46.99  ? 514 TRP A CE2   1 
ATOM   4032  C CE3   . TRP A 1 514 ? -14.995 -10.974 -13.987  1.00 44.34  ? 514 TRP A CE3   1 
ATOM   4033  C CZ2   . TRP A 1 514 ? -16.844 -11.162 -16.108  1.00 47.05  ? 514 TRP A CZ2   1 
ATOM   4034  C CZ3   . TRP A 1 514 ? -15.239 -12.175 -14.618  1.00 40.04  ? 514 TRP A CZ3   1 
ATOM   4035  C CH2   . TRP A 1 514 ? -16.158 -12.268 -15.656  1.00 40.45  ? 514 TRP A CH2   1 
ATOM   4036  N N     . GLY A 1 515 ? -14.004 -7.012  -9.974   1.00 45.84  ? 515 GLY A N     1 
ATOM   4037  C CA    . GLY A 1 515 ? -12.968 -6.812  -8.972   1.00 45.97  ? 515 GLY A CA    1 
ATOM   4038  C C     . GLY A 1 515 ? -11.604 -6.617  -9.615   1.00 41.13  ? 515 GLY A C     1 
ATOM   4039  O O     . GLY A 1 515 ? -11.452 -6.933  -10.772  1.00 51.57  ? 515 GLY A O     1 
ATOM   4040  N N     . LYS A 1 516 ? -10.607 -6.129  -8.875   1.00 51.37  ? 516 LYS A N     1 
ATOM   4041  C CA    . LYS A 1 516 ? -9.427  -5.531  -9.496   1.00 52.48  ? 516 LYS A CA    1 
ATOM   4042  C C     . LYS A 1 516 ? -8.574  -6.604  -10.173  1.00 52.28  ? 516 LYS A C     1 
ATOM   4043  O O     . LYS A 1 516 ? -7.902  -6.320  -11.159  1.00 56.02  ? 516 LYS A O     1 
ATOM   4044  C CB    . LYS A 1 516 ? -8.616  -4.663  -8.517   1.00 57.96  ? 516 LYS A CB    1 
ATOM   4045  C CG    . LYS A 1 516 ? -8.237  -5.294  -7.181   1.00 67.02  ? 516 LYS A CG    1 
ATOM   4046  C CD    . LYS A 1 516 ? -7.153  -4.531  -6.414   1.00 80.69  ? 516 LYS A CD    1 
ATOM   4047  C CE    . LYS A 1 516 ? -7.162  -4.745  -4.906   1.00 87.67  ? 516 LYS A CE    1 
ATOM   4048  N NZ    . LYS A 1 516 ? -6.686  -6.090  -4.481   1.00 85.12  ? 516 LYS A NZ    1 
ATOM   4049  N N     . ASN A 1 517 ? -8.645  -7.847  -9.690   1.00 54.49  ? 517 ASN A N     1 
ATOM   4050  C CA    . ASN A 1 517 ? -7.826  -8.922  -10.230  1.00 53.29  ? 517 ASN A CA    1 
ATOM   4051  C C     . ASN A 1 517 ? -8.325  -9.419  -11.595  1.00 55.37  ? 517 ASN A C     1 
ATOM   4052  O O     . ASN A 1 517 ? -7.546  -10.019 -12.317  1.00 67.04  ? 517 ASN A O     1 
ATOM   4053  C CB    . ASN A 1 517 ? -7.712  -10.105 -9.253   1.00 50.38  ? 517 ASN A CB    1 
ATOM   4054  C CG    . ASN A 1 517 ? -7.033  -9.746  -7.944   1.00 58.87  ? 517 ASN A CG    1 
ATOM   4055  O OD1   . ASN A 1 517 ? -6.083  -8.968  -7.917   1.00 67.60  ? 517 ASN A OD1   1 
ATOM   4056  N ND2   . ASN A 1 517 ? -7.528  -10.277 -6.838   1.00 61.80  ? 517 ASN A ND2   1 
ATOM   4057  N N     . ARG A 1 518 ? -9.608  -9.250  -11.951  1.00 62.12  ? 518 ARG A N     1 
ATOM   4058  C CA    . ARG A 1 518 ? -10.122 -9.787  -13.212  1.00 64.17  ? 518 ARG A CA    1 
ATOM   4059  C C     . ARG A 1 518 ? -10.489 -8.628  -14.143  1.00 60.98  ? 518 ARG A C     1 
ATOM   4060  O O     . ARG A 1 518 ? -11.013 -8.809  -15.231  1.00 69.46  ? 518 ARG A O     1 
ATOM   4061  C CB    . ARG A 1 518 ? -11.246 -10.807 -12.946  1.00 60.00  ? 518 ARG A CB    1 
ATOM   4062  C CG    . ARG A 1 518 ? -10.727 -12.114 -12.363  1.00 64.32  ? 518 ARG A CG    1 
ATOM   4063  C CD    . ARG A 1 518 ? -11.771 -13.124 -11.933  1.00 80.28  ? 518 ARG A CD    1 
ATOM   4064  N NE    . ARG A 1 518 ? -11.429 -13.772 -10.656  1.00 90.15  ? 518 ARG A NE    1 
ATOM   4065  C CZ    . ARG A 1 518 ? -10.929 -15.003 -10.500  1.00 100.74 ? 518 ARG A CZ    1 
ATOM   4066  N NH1   . ARG A 1 518 ? -10.556 -15.735 -11.540  1.00 95.14  ? 518 ARG A NH1   1 
ATOM   4067  N NH2   . ARG A 1 518 ? -10.770 -15.493 -9.281   1.00 110.72 ? 518 ARG A NH2   1 
ATOM   4068  N N     . ARG A 1 519 ? -10.118 -7.423  -13.743  1.00 67.86  ? 519 ARG A N     1 
ATOM   4069  C CA    . ARG A 1 519 ? -10.468 -6.213  -14.455  1.00 68.89  ? 519 ARG A CA    1 
ATOM   4070  C C     . ARG A 1 519 ? -9.134  -5.572  -14.871  1.00 59.72  ? 519 ARG A C     1 
ATOM   4071  O O     . ARG A 1 519 ? -8.980  -5.318  -16.067  1.00 63.02  ? 519 ARG A O     1 
ATOM   4072  C CB    . ARG A 1 519 ? -11.361 -5.422  -13.486  1.00 61.43  ? 519 ARG A CB    1 
ATOM   4073  C CG    . ARG A 1 519 ? -11.878 -4.085  -13.989  1.00 64.92  ? 519 ARG A CG    1 
ATOM   4074  C CD    . ARG A 1 519 ? -12.617 -3.326  -12.888  1.00 62.93  ? 519 ARG A CD    1 
ATOM   4075  N NE    . ARG A 1 519 ? -11.771 -2.576  -11.953  1.00 60.17  ? 519 ARG A NE    1 
ATOM   4076  C CZ    . ARG A 1 519 ? -11.764 -2.688  -10.613  1.00 58.58  ? 519 ARG A CZ    1 
ATOM   4077  N NH1   . ARG A 1 519 ? -12.615 -3.470  -9.968   1.00 53.03  ? 519 ARG A NH1   1 
ATOM   4078  N NH2   . ARG A 1 519 ? -10.868 -2.022  -9.904   1.00 59.20  ? 519 ARG A NH2   1 
ATOM   4079  N N     . ALA B 1 2   ? 9.233   10.280  -19.073  1.00 107.25 ? 2   ALA B N     1 
ATOM   4080  C CA    . ALA B 1 2   ? 9.870   9.250   -19.934  1.00 123.39 ? 2   ALA B CA    1 
ATOM   4081  C C     . ALA B 1 2   ? 8.834   8.183   -20.284  1.00 136.27 ? 2   ALA B C     1 
ATOM   4082  O O     . ALA B 1 2   ? 7.968   7.880   -19.464  1.00 123.74 ? 2   ALA B O     1 
ATOM   4083  C CB    . ALA B 1 2   ? 11.083  8.652   -19.250  1.00 118.69 ? 2   ALA B CB    1 
ATOM   4084  N N     . ALA B 1 3   ? 8.937   7.617   -21.498  1.00 134.50 ? 3   ALA B N     1 
ATOM   4085  C CA    . ALA B 1 3   ? 7.899   6.765   -22.062  1.00 118.20 ? 3   ALA B CA    1 
ATOM   4086  C C     . ALA B 1 3   ? 8.292   5.286   -21.963  1.00 98.48  ? 3   ALA B C     1 
ATOM   4087  O O     . ALA B 1 3   ? 9.445   4.920   -22.223  1.00 75.37  ? 3   ALA B O     1 
ATOM   4088  C CB    . ALA B 1 3   ? 7.624   7.186   -23.490  1.00 124.00 ? 3   ALA B CB    1 
ATOM   4089  N N     . PRO B 1 4   ? 7.347   4.394   -21.561  1.00 94.89  ? 4   PRO B N     1 
ATOM   4090  C CA    . PRO B 1 4   ? 7.641   2.967   -21.408  1.00 96.02  ? 4   PRO B CA    1 
ATOM   4091  C C     . PRO B 1 4   ? 7.607   2.219   -22.738  1.00 85.83  ? 4   PRO B C     1 
ATOM   4092  O O     . PRO B 1 4   ? 7.223   2.776   -23.761  1.00 80.84  ? 4   PRO B O     1 
ATOM   4093  C CB    . PRO B 1 4   ? 6.543   2.467   -20.446  1.00 95.02  ? 4   PRO B CB    1 
ATOM   4094  C CG    . PRO B 1 4   ? 5.368   3.414   -20.658  1.00 99.22  ? 4   PRO B CG    1 
ATOM   4095  C CD    . PRO B 1 4   ? 5.958   4.713   -21.177  1.00 98.46  ? 4   PRO B CD    1 
ATOM   4096  N N     . LEU B 1 5   ? 8.019   0.949   -22.699  1.00 87.82  ? 5   LEU B N     1 
ATOM   4097  C CA    . LEU B 1 5   ? 7.940   0.071   -23.857  1.00 89.53  ? 5   LEU B CA    1 
ATOM   4098  C C     . LEU B 1 5   ? 6.478   -0.236  -24.171  1.00 88.27  ? 5   LEU B C     1 
ATOM   4099  O O     . LEU B 1 5   ? 5.632   -0.186  -23.282  1.00 93.84  ? 5   LEU B O     1 
ATOM   4100  C CB    . LEU B 1 5   ? 8.699   -1.234  -23.577  1.00 86.68  ? 5   LEU B CB    1 
ATOM   4101  C CG    . LEU B 1 5   ? 10.226  -1.154  -23.574  1.00 86.89  ? 5   LEU B CG    1 
ATOM   4102  C CD1   . LEU B 1 5   ? 10.827  -2.514  -23.253  1.00 96.94  ? 5   LEU B CD1   1 
ATOM   4103  C CD2   . LEU B 1 5   ? 10.774  -0.654  -24.902  1.00 81.49  ? 5   LEU B CD2   1 
ATOM   4104  N N     . PRO B 1 6   ? 6.136   -0.569  -25.439  1.00 88.90  ? 6   PRO B N     1 
ATOM   4105  C CA    . PRO B 1 6   ? 4.849   -1.186  -25.752  1.00 83.62  ? 6   PRO B CA    1 
ATOM   4106  C C     . PRO B 1 6   ? 4.792   -2.630  -25.257  1.00 83.86  ? 6   PRO B C     1 
ATOM   4107  O O     . PRO B 1 6   ? 5.727   -3.416  -25.433  1.00 82.45  ? 6   PRO B O     1 
ATOM   4108  C CB    . PRO B 1 6   ? 4.764   -1.115  -27.278  1.00 88.27  ? 6   PRO B CB    1 
ATOM   4109  C CG    . PRO B 1 6   ? 6.214   -1.095  -27.729  1.00 89.79  ? 6   PRO B CG    1 
ATOM   4110  C CD    . PRO B 1 6   ? 6.966   -0.370  -26.636  1.00 85.90  ? 6   PRO B CD    1 
ATOM   4111  N N     . GLU B 1 7   ? 3.670   -2.940  -24.615  1.00 78.26  ? 7   GLU B N     1 
ATOM   4112  C CA    . GLU B 1 7   ? 3.408   -4.228  -24.002  1.00 85.02  ? 7   GLU B CA    1 
ATOM   4113  C C     . GLU B 1 7   ? 3.700   -5.359  -24.993  1.00 82.82  ? 7   GLU B C     1 
ATOM   4114  O O     . GLU B 1 7   ? 3.225   -5.333  -26.124  1.00 93.95  ? 7   GLU B O     1 
ATOM   4115  C CB    . GLU B 1 7   ? 1.950   -4.191  -23.533  1.00 97.89  ? 7   GLU B CB    1 
ATOM   4116  C CG    . GLU B 1 7   ? 1.528   -5.353  -22.665  1.00 107.53 ? 7   GLU B CG    1 
ATOM   4117  C CD    . GLU B 1 7   ? 0.158   -5.157  -22.041  1.00 116.71 ? 7   GLU B CD    1 
ATOM   4118  O OE1   . GLU B 1 7   ? -0.393  -4.045  -22.159  1.00 129.21 ? 7   GLU B OE1   1 
ATOM   4119  O OE2   . GLU B 1 7   ? -0.357  -6.117  -21.448  1.00 113.56 ? 7   GLU B OE2   1 
ATOM   4120  N N     . GLY B 1 8   ? 4.492   -6.348  -24.550  1.00 83.17  ? 8   GLY B N     1 
ATOM   4121  C CA    . GLY B 1 8   ? 4.868   -7.505  -25.350  1.00 72.32  ? 8   GLY B CA    1 
ATOM   4122  C C     . GLY B 1 8   ? 6.226   -7.320  -26.021  1.00 74.06  ? 8   GLY B C     1 
ATOM   4123  O O     . GLY B 1 8   ? 6.750   -8.250  -26.616  1.00 73.86  ? 8   GLY B O     1 
ATOM   4124  N N     . VAL B 1 9   ? 6.782   -6.105  -25.938  1.00 76.81  ? 9   VAL B N     1 
ATOM   4125  C CA    . VAL B 1 9   ? 7.991   -5.769  -26.672  1.00 84.79  ? 9   VAL B CA    1 
ATOM   4126  C C     . VAL B 1 9   ? 9.149   -5.579  -25.689  1.00 90.82  ? 9   VAL B C     1 
ATOM   4127  O O     . VAL B 1 9   ? 9.118   -4.723  -24.798  1.00 78.86  ? 9   VAL B O     1 
ATOM   4128  C CB    . VAL B 1 9   ? 7.791   -4.521  -27.552  1.00 81.92  ? 9   VAL B CB    1 
ATOM   4129  C CG1   . VAL B 1 9   ? 8.974   -4.294  -28.483  1.00 71.77  ? 9   VAL B CG1   1 
ATOM   4130  C CG2   . VAL B 1 9   ? 6.495   -4.605  -28.340  1.00 81.03  ? 9   VAL B CG2   1 
ATOM   4131  N N     . SER B 1 10  ? 10.184  -6.398  -25.896  1.00 93.91  ? 10  SER B N     1 
ATOM   4132  C CA    . SER B 1 10  ? 11.399  -6.343  -25.109  1.00 91.23  ? 10  SER B CA    1 
ATOM   4133  C C     . SER B 1 10  ? 12.251  -5.163  -25.560  1.00 98.54  ? 10  SER B C     1 
ATOM   4134  O O     . SER B 1 10  ? 12.028  -4.604  -26.631  1.00 110.46 ? 10  SER B O     1 
ATOM   4135  C CB    . SER B 1 10  ? 12.144  -7.645  -25.215  1.00 87.27  ? 10  SER B CB    1 
ATOM   4136  O OG    . SER B 1 10  ? 12.304  -8.026  -26.567  1.00 76.22  ? 10  SER B OG    1 
ATOM   4137  N N     . ALA B 1 11  ? 13.223  -4.793  -24.722  1.00 100.25 ? 11  ALA B N     1 
ATOM   4138  C CA    . ALA B 1 11  ? 14.113  -3.680  -25.005  1.00 90.14  ? 11  ALA B CA    1 
ATOM   4139  C C     . ALA B 1 11  ? 15.086  -4.045  -26.124  1.00 84.66  ? 11  ALA B C     1 
ATOM   4140  O O     . ALA B 1 11  ? 15.528  -3.144  -26.834  1.00 88.41  ? 11  ALA B O     1 
ATOM   4141  C CB    . ALA B 1 11  ? 14.834  -3.268  -23.744  1.00 89.29  ? 11  ALA B CB    1 
ATOM   4142  N N     . GLU B 1 12  ? 15.395  -5.346  -26.291  1.00 91.77  ? 12  GLU B N     1 
ATOM   4143  C CA    . GLU B 1 12  ? 16.311  -5.798  -27.338  1.00 111.07 ? 12  GLU B CA    1 
ATOM   4144  C C     . GLU B 1 12  ? 15.626  -5.716  -28.696  1.00 110.36 ? 12  GLU B C     1 
ATOM   4145  O O     . GLU B 1 12  ? 16.228  -5.272  -29.674  1.00 102.90 ? 12  GLU B O     1 
ATOM   4146  C CB    . GLU B 1 12  ? 16.769  -7.257  -27.213  1.00 116.29 ? 12  GLU B CB    1 
ATOM   4147  C CG    . GLU B 1 12  ? 17.493  -7.589  -25.927  1.00 123.87 ? 12  GLU B CG    1 
ATOM   4148  C CD    . GLU B 1 12  ? 16.534  -7.826  -24.778  1.00 124.05 ? 12  GLU B CD    1 
ATOM   4149  O OE1   . GLU B 1 12  ? 16.648  -7.129  -23.751  1.00 117.30 ? 12  GLU B OE1   1 
ATOM   4150  O OE2   . GLU B 1 12  ? 15.644  -8.679  -24.941  1.00 118.96 ? 12  GLU B OE2   1 
ATOM   4151  N N     . ALA B 1 13  ? 14.380  -6.205  -28.744  1.00 111.84 ? 13  ALA B N     1 
ATOM   4152  C CA    . ALA B 1 13  ? 13.576  -6.143  -29.953  1.00 110.23 ? 13  ALA B CA    1 
ATOM   4153  C C     . ALA B 1 13  ? 13.399  -4.683  -30.385  1.00 111.53 ? 13  ALA B C     1 
ATOM   4154  O O     . ALA B 1 13  ? 13.409  -4.393  -31.578  1.00 113.94 ? 13  ALA B O     1 
ATOM   4155  C CB    . ALA B 1 13  ? 12.253  -6.849  -29.743  1.00 94.51  ? 13  ALA B CB    1 
ATOM   4156  N N     . MET B 1 14  ? 13.282  -3.758  -29.421  1.00 106.82 ? 14  MET B N     1 
ATOM   4157  C CA    . MET B 1 14  ? 13.199  -2.337  -29.729  1.00 103.19 ? 14  MET B CA    1 
ATOM   4158  C C     . MET B 1 14  ? 14.537  -1.850  -30.291  1.00 111.86 ? 14  MET B C     1 
ATOM   4159  O O     . MET B 1 14  ? 14.576  -1.384  -31.431  1.00 98.24  ? 14  MET B O     1 
ATOM   4160  C CB    . MET B 1 14  ? 12.820  -1.518  -28.487  1.00 104.95 ? 14  MET B CB    1 
ATOM   4161  C CG    . MET B 1 14  ? 12.663  -0.020  -28.747  1.00 110.73 ? 14  MET B CG    1 
ATOM   4162  S SD    . MET B 1 14  ? 11.370  0.386   -29.975  1.00 101.37 ? 14  MET B SD    1 
ATOM   4163  C CE    . MET B 1 14  ? 9.896   0.228   -28.969  1.00 96.68  ? 14  MET B CE    1 
ATOM   4164  N N     . SER B 1 15  ? 15.620  -1.992  -29.502  1.00 116.48 ? 15  SER B N     1 
ATOM   4165  C CA    . SER B 1 15  ? 16.954  -1.520  -29.869  1.00 105.57 ? 15  SER B CA    1 
ATOM   4166  C C     . SER B 1 15  ? 17.344  -1.959  -31.280  1.00 99.52  ? 15  SER B C     1 
ATOM   4167  O O     . SER B 1 15  ? 17.850  -1.151  -32.050  1.00 98.79  ? 15  SER B O     1 
ATOM   4168  C CB    . SER B 1 15  ? 17.991  -1.984  -28.883  1.00 97.95  ? 15  SER B CB    1 
ATOM   4169  O OG    . SER B 1 15  ? 17.624  -1.608  -27.571  1.00 95.65  ? 15  SER B OG    1 
ATOM   4170  N N     . SER B 1 16  ? 17.133  -3.242  -31.600  1.00 97.51  ? 16  SER B N     1 
ATOM   4171  C CA    . SER B 1 16  ? 17.518  -3.796  -32.891  1.00 105.23 ? 16  SER B CA    1 
ATOM   4172  C C     . SER B 1 16  ? 16.676  -3.192  -34.016  1.00 107.03 ? 16  SER B C     1 
ATOM   4173  O O     . SER B 1 16  ? 17.150  -3.061  -35.147  1.00 115.29 ? 16  SER B O     1 
ATOM   4174  C CB    . SER B 1 16  ? 17.399  -5.302  -32.894  1.00 107.76 ? 16  SER B CB    1 
ATOM   4175  O OG    . SER B 1 16  ? 17.876  -5.848  -31.678  1.00 112.70 ? 16  SER B OG    1 
ATOM   4176  N N     . ALA B 1 17  ? 15.417  -2.850  -33.698  1.00 98.63  ? 17  ALA B N     1 
ATOM   4177  C CA    . ALA B 1 17  ? 14.482  -2.319  -34.677  1.00 80.64  ? 17  ALA B CA    1 
ATOM   4178  C C     . ALA B 1 17  ? 14.771  -0.844  -34.957  1.00 67.51  ? 17  ALA B C     1 
ATOM   4179  O O     . ALA B 1 17  ? 14.812  -0.451  -36.126  1.00 64.55  ? 17  ALA B O     1 
ATOM   4180  C CB    . ALA B 1 17  ? 13.064  -2.529  -34.214  1.00 84.01  ? 17  ALA B CB    1 
ATOM   4181  N N     . LEU B 1 18  ? 14.977  -0.040  -33.900  1.00 62.89  ? 18  LEU B N     1 
ATOM   4182  C CA    . LEU B 1 18  ? 15.398  1.350   -34.071  1.00 75.64  ? 18  LEU B CA    1 
ATOM   4183  C C     . LEU B 1 18  ? 16.716  1.421   -34.839  1.00 77.27  ? 18  LEU B C     1 
ATOM   4184  O O     . LEU B 1 18  ? 17.052  2.475   -35.363  1.00 69.96  ? 18  LEU B O     1 
ATOM   4185  C CB    . LEU B 1 18  ? 15.588  2.054   -32.720  1.00 73.57  ? 18  LEU B CB    1 
ATOM   4186  C CG    . LEU B 1 18  ? 14.330  2.388   -31.916  1.00 77.73  ? 18  LEU B CG    1 
ATOM   4187  C CD1   . LEU B 1 18  ? 14.693  2.854   -30.511  1.00 82.73  ? 18  LEU B CD1   1 
ATOM   4188  C CD2   . LEU B 1 18  ? 13.493  3.460   -32.596  1.00 77.83  ? 18  LEU B CD2   1 
ATOM   4189  N N     . ASP B 1 19  ? 17.483  0.320   -34.846  1.00 81.33  ? 19  ASP B N     1 
ATOM   4190  C CA    . ASP B 1 19  ? 18.813  0.337   -35.425  1.00 87.95  ? 19  ASP B CA    1 
ATOM   4191  C C     . ASP B 1 19  ? 18.680  0.050   -36.910  1.00 77.76  ? 19  ASP B C     1 
ATOM   4192  O O     . ASP B 1 19  ? 19.298  0.723   -37.736  1.00 80.15  ? 19  ASP B O     1 
ATOM   4193  C CB    . ASP B 1 19  ? 19.765  -0.653  -34.748  1.00 103.19 ? 19  ASP B CB    1 
ATOM   4194  C CG    . ASP B 1 19  ? 21.186  -0.124  -34.690  1.00 107.30 ? 19  ASP B CG    1 
ATOM   4195  O OD1   . ASP B 1 19  ? 21.440  0.719   -33.806  1.00 95.66  ? 19  ASP B OD1   1 
ATOM   4196  O OD2   . ASP B 1 19  ? 22.004  -0.509  -35.565  1.00 112.07 ? 19  ASP B OD2   1 
ATOM   4197  N N     . ARG B 1 20  ? 17.853  -0.945  -37.231  1.00 74.21  ? 20  ARG B N     1 
ATOM   4198  C CA    . ARG B 1 20  ? 17.457  -1.155  -38.615  1.00 81.95  ? 20  ARG B CA    1 
ATOM   4199  C C     . ARG B 1 20  ? 16.703  0.065   -39.189  1.00 75.80  ? 20  ARG B C     1 
ATOM   4200  O O     . ARG B 1 20  ? 16.754  0.294   -40.389  1.00 68.31  ? 20  ARG B O     1 
ATOM   4201  C CB    . ARG B 1 20  ? 16.646  -2.448  -38.731  1.00 87.40  ? 20  ARG B CB    1 
ATOM   4202  C CG    . ARG B 1 20  ? 17.451  -3.745  -38.734  1.00 83.44  ? 20  ARG B CG    1 
ATOM   4203  C CD    . ARG B 1 20  ? 16.674  -4.725  -39.592  1.00 80.46  ? 20  ARG B CD    1 
ATOM   4204  N NE    . ARG B 1 20  ? 17.052  -6.124  -39.550  1.00 85.14  ? 20  ARG B NE    1 
ATOM   4205  C CZ    . ARG B 1 20  ? 16.540  -7.062  -40.354  1.00 99.13  ? 20  ARG B CZ    1 
ATOM   4206  N NH1   . ARG B 1 20  ? 15.696  -6.718  -41.313  1.00 99.02  ? 20  ARG B NH1   1 
ATOM   4207  N NH2   . ARG B 1 20  ? 16.883  -8.337  -40.224  1.00 95.48  ? 20  ARG B NH2   1 
ATOM   4208  N N     . PHE B 1 21  ? 15.993  0.868   -38.379  1.00 71.31  ? 21  PHE B N     1 
ATOM   4209  C CA    . PHE B 1 21  ? 15.299  2.033   -38.916  1.00 68.83  ? 21  PHE B CA    1 
ATOM   4210  C C     . PHE B 1 21  ? 16.335  3.061   -39.363  1.00 77.44  ? 21  PHE B C     1 
ATOM   4211  O O     . PHE B 1 21  ? 16.151  3.737   -40.379  1.00 70.43  ? 21  PHE B O     1 
ATOM   4212  C CB    . PHE B 1 21  ? 14.321  2.663   -37.907  1.00 67.09  ? 21  PHE B CB    1 
ATOM   4213  C CG    . PHE B 1 21  ? 13.093  1.868   -37.510  1.00 60.76  ? 21  PHE B CG    1 
ATOM   4214  C CD1   . PHE B 1 21  ? 12.565  0.868   -38.310  1.00 64.80  ? 21  PHE B CD1   1 
ATOM   4215  C CD2   . PHE B 1 21  ? 12.454  2.127   -36.309  1.00 67.25  ? 21  PHE B CD2   1 
ATOM   4216  C CE1   . PHE B 1 21  ? 11.446  0.142   -37.921  1.00 66.23  ? 21  PHE B CE1   1 
ATOM   4217  C CE2   . PHE B 1 21  ? 11.343  1.393   -35.914  1.00 69.31  ? 21  PHE B CE2   1 
ATOM   4218  C CZ    . PHE B 1 21  ? 10.844  0.395   -36.717  1.00 64.16  ? 21  PHE B CZ    1 
ATOM   4219  N N     . ALA B 1 22  ? 17.433  3.146   -38.594  1.00 86.89  ? 22  ALA B N     1 
ATOM   4220  C CA    . ALA B 1 22  ? 18.501  4.109   -38.825  1.00 78.42  ? 22  ALA B CA    1 
ATOM   4221  C C     . ALA B 1 22  ? 19.276  3.774   -40.097  1.00 68.97  ? 22  ALA B C     1 
ATOM   4222  O O     . ALA B 1 22  ? 19.725  4.671   -40.797  1.00 71.72  ? 22  ALA B O     1 
ATOM   4223  C CB    . ALA B 1 22  ? 19.402  4.150   -37.622  1.00 75.14  ? 22  ALA B CB    1 
ATOM   4224  N N     . ARG B 1 23  ? 19.402  2.487   -40.415  1.00 70.89  ? 23  ARG B N     1 
ATOM   4225  C CA    . ARG B 1 23  ? 20.046  2.075   -41.653  1.00 90.83  ? 23  ARG B CA    1 
ATOM   4226  C C     . ARG B 1 23  ? 19.217  2.511   -42.865  1.00 96.76  ? 23  ARG B C     1 
ATOM   4227  O O     . ARG B 1 23  ? 19.773  2.805   -43.924  1.00 101.67 ? 23  ARG B O     1 
ATOM   4228  C CB    . ARG B 1 23  ? 20.274  0.557   -41.677  1.00 108.17 ? 23  ARG B CB    1 
ATOM   4229  C CG    . ARG B 1 23  ? 21.244  0.034   -40.622  1.00 123.09 ? 23  ARG B CG    1 
ATOM   4230  C CD    . ARG B 1 23  ? 21.377  -1.486  -40.642  1.00 131.86 ? 23  ARG B CD    1 
ATOM   4231  N NE    . ARG B 1 23  ? 21.834  -2.023  -39.361  1.00 139.60 ? 23  ARG B NE    1 
ATOM   4232  C CZ    . ARG B 1 23  ? 21.755  -3.301  -38.984  1.00 127.30 ? 23  ARG B CZ    1 
ATOM   4233  N NH1   . ARG B 1 23  ? 21.250  -4.219  -39.792  1.00 109.75 ? 23  ARG B NH1   1 
ATOM   4234  N NH2   . ARG B 1 23  ? 22.186  -3.657  -37.785  1.00 122.12 ? 23  ARG B NH2   1 
ATOM   4235  N N     . ILE B 1 24  ? 17.886  2.561   -42.708  1.00 96.01  ? 24  ILE B N     1 
ATOM   4236  C CA    . ILE B 1 24  ? 16.979  2.790   -43.825  1.00 77.98  ? 24  ILE B CA    1 
ATOM   4237  C C     . ILE B 1 24  ? 16.880  4.287   -44.139  1.00 73.99  ? 24  ILE B C     1 
ATOM   4238  O O     . ILE B 1 24  ? 16.988  4.671   -45.301  1.00 79.10  ? 24  ILE B O     1 
ATOM   4239  C CB    . ILE B 1 24  ? 15.602  2.152   -43.541  1.00 77.21  ? 24  ILE B CB    1 
ATOM   4240  C CG1   . ILE B 1 24  ? 15.688  0.622   -43.450  1.00 84.39  ? 24  ILE B CG1   1 
ATOM   4241  C CG2   . ILE B 1 24  ? 14.590  2.578   -44.588  1.00 73.61  ? 24  ILE B CG2   1 
ATOM   4242  C CD1   . ILE B 1 24  ? 14.517  -0.052  -42.733  1.00 85.16  ? 24  ILE B CD1   1 
ATOM   4243  N N     . VAL B 1 25  ? 16.676  5.132   -43.114  1.00 69.36  ? 25  VAL B N     1 
ATOM   4244  C CA    . VAL B 1 25  ? 16.327  6.532   -43.339  1.00 73.78  ? 25  VAL B CA    1 
ATOM   4245  C C     . VAL B 1 25  ? 17.510  7.449   -43.053  1.00 74.87  ? 25  VAL B C     1 
ATOM   4246  O O     . VAL B 1 25  ? 17.440  8.627   -43.377  1.00 81.65  ? 25  VAL B O     1 
ATOM   4247  C CB    . VAL B 1 25  ? 15.112  6.969   -42.491  1.00 78.43  ? 25  VAL B CB    1 
ATOM   4248  C CG1   . VAL B 1 25  ? 13.899  6.072   -42.724  1.00 84.53  ? 25  VAL B CG1   1 
ATOM   4249  C CG2   . VAL B 1 25  ? 15.426  7.057   -41.002  1.00 74.76  ? 25  VAL B CG2   1 
ATOM   4250  N N     . GLY B 1 26  ? 18.559  6.914   -42.413  1.00 92.57  ? 26  GLY B N     1 
ATOM   4251  C CA    . GLY B 1 26  ? 19.667  7.703   -41.897  1.00 91.69  ? 26  GLY B CA    1 
ATOM   4252  C C     . GLY B 1 26  ? 19.642  7.773   -40.373  1.00 93.24  ? 26  GLY B C     1 
ATOM   4253  O O     . GLY B 1 26  ? 18.624  7.497   -39.749  1.00 96.55  ? 26  GLY B O     1 
ATOM   4254  N N     . ALA B 1 27  ? 20.782  8.140   -39.782  1.00 100.18 ? 27  ALA B N     1 
ATOM   4255  C CA    . ALA B 1 27  ? 20.894  8.271   -38.340  1.00 97.58  ? 27  ALA B CA    1 
ATOM   4256  C C     . ALA B 1 27  ? 20.255  9.583   -37.893  1.00 92.55  ? 27  ALA B C     1 
ATOM   4257  O O     . ALA B 1 27  ? 19.849  9.715   -36.741  1.00 93.57  ? 27  ALA B O     1 
ATOM   4258  C CB    . ALA B 1 27  ? 22.345  8.191   -37.927  1.00 97.16  ? 27  ALA B CB    1 
ATOM   4259  N N     . ASP B 1 28  ? 20.142  10.540  -38.820  1.00 91.11  ? 28  ASP B N     1 
ATOM   4260  C CA    . ASP B 1 28  ? 19.716  11.888  -38.480  1.00 89.80  ? 28  ASP B CA    1 
ATOM   4261  C C     . ASP B 1 28  ? 18.205  11.965  -38.326  1.00 84.95  ? 28  ASP B C     1 
ATOM   4262  O O     . ASP B 1 28  ? 17.700  12.940  -37.770  1.00 75.69  ? 28  ASP B O     1 
ATOM   4263  C CB    . ASP B 1 28  ? 20.142  12.891  -39.553  1.00 99.09  ? 28  ASP B CB    1 
ATOM   4264  C CG    . ASP B 1 28  ? 21.644  13.093  -39.643  1.00 95.59  ? 28  ASP B CG    1 
ATOM   4265  O OD1   . ASP B 1 28  ? 22.374  12.500  -38.810  1.00 84.49  ? 28  ASP B OD1   1 
ATOM   4266  O OD2   . ASP B 1 28  ? 22.067  13.835  -40.548  1.00 81.48  ? 28  ASP B OD2   1 
ATOM   4267  N N     . TRP B 1 29  ? 17.503  10.951  -38.853  1.00 91.16  ? 29  TRP B N     1 
ATOM   4268  C CA    . TRP B 1 29  ? 16.050  10.963  -38.900  1.00 86.64  ? 29  TRP B CA    1 
ATOM   4269  C C     . TRP B 1 29  ? 15.457  9.840   -38.059  1.00 82.29  ? 29  TRP B C     1 
ATOM   4270  O O     . TRP B 1 29  ? 14.549  9.162   -38.534  1.00 75.46  ? 29  TRP B O     1 
ATOM   4271  C CB    . TRP B 1 29  ? 15.592  10.846  -40.352  1.00 83.83  ? 29  TRP B CB    1 
ATOM   4272  C CG    . TRP B 1 29  ? 16.236  11.849  -41.254  1.00 73.37  ? 29  TRP B CG    1 
ATOM   4273  C CD1   . TRP B 1 29  ? 17.189  11.603  -42.199  1.00 61.61  ? 29  TRP B CD1   1 
ATOM   4274  C CD2   . TRP B 1 29  ? 15.951  13.260  -41.314  1.00 64.21  ? 29  TRP B CD2   1 
ATOM   4275  N NE1   . TRP B 1 29  ? 17.519  12.768  -42.842  1.00 70.37  ? 29  TRP B NE1   1 
ATOM   4276  C CE2   . TRP B 1 29  ? 16.786  13.803  -42.323  1.00 65.34  ? 29  TRP B CE2   1 
ATOM   4277  C CE3   . TRP B 1 29  ? 15.070  14.112  -40.634  1.00 58.38  ? 29  TRP B CE3   1 
ATOM   4278  C CZ2   . TRP B 1 29  ? 16.773  15.156  -42.661  1.00 58.91  ? 29  TRP B CZ2   1 
ATOM   4279  C CZ3   . TRP B 1 29  ? 15.048  15.455  -40.976  1.00 64.07  ? 29  TRP B CZ3   1 
ATOM   4280  C CH2   . TRP B 1 29  ? 15.901  15.970  -41.964  1.00 62.20  ? 29  TRP B CH2   1 
ATOM   4281  N N     . VAL B 1 30  ? 15.973  9.651   -36.832  1.00 73.42  ? 30  VAL B N     1 
ATOM   4282  C CA    . VAL B 1 30  ? 15.378  8.730   -35.877  1.00 74.07  ? 30  VAL B CA    1 
ATOM   4283  C C     . VAL B 1 30  ? 15.402  9.382   -34.500  1.00 73.75  ? 30  VAL B C     1 
ATOM   4284  O O     . VAL B 1 30  ? 16.391  9.266   -33.798  1.00 94.50  ? 30  VAL B O     1 
ATOM   4285  C CB    . VAL B 1 30  ? 16.083  7.360   -35.851  1.00 71.28  ? 30  VAL B CB    1 
ATOM   4286  C CG1   . VAL B 1 30  ? 15.476  6.424   -34.811  1.00 64.48  ? 30  VAL B CG1   1 
ATOM   4287  C CG2   . VAL B 1 30  ? 16.096  6.698   -37.222  1.00 77.21  ? 30  VAL B CG2   1 
ATOM   4288  N N     . PHE B 1 31  ? 14.286  9.996   -34.098  1.00 74.76  ? 31  PHE B N     1 
ATOM   4289  C CA    . PHE B 1 31  ? 14.238  10.843  -32.920  1.00 79.51  ? 31  PHE B CA    1 
ATOM   4290  C C     . PHE B 1 31  ? 13.811  10.047  -31.689  1.00 88.16  ? 31  PHE B C     1 
ATOM   4291  O O     . PHE B 1 31  ? 12.658  9.637   -31.603  1.00 91.58  ? 31  PHE B O     1 
ATOM   4292  C CB    . PHE B 1 31  ? 13.281  12.003  -33.188  1.00 87.67  ? 31  PHE B CB    1 
ATOM   4293  C CG    . PHE B 1 31  ? 13.562  12.727  -34.483  1.00 90.37  ? 31  PHE B CG    1 
ATOM   4294  C CD1   . PHE B 1 31  ? 14.785  13.337  -34.704  1.00 81.12  ? 31  PHE B CD1   1 
ATOM   4295  C CD2   . PHE B 1 31  ? 12.611  12.778  -35.491  1.00 99.64  ? 31  PHE B CD2   1 
ATOM   4296  C CE1   . PHE B 1 31  ? 15.043  13.996  -35.895  1.00 85.91  ? 31  PHE B CE1   1 
ATOM   4297  C CE2   . PHE B 1 31  ? 12.867  13.447  -36.677  1.00 97.32  ? 31  PHE B CE2   1 
ATOM   4298  C CZ    . PHE B 1 31  ? 14.085  14.050  -36.879  1.00 93.44  ? 31  PHE B CZ    1 
ATOM   4299  N N     . THR B 1 32  ? 14.763  9.828   -30.762  1.00 101.05 ? 32  THR B N     1 
ATOM   4300  C CA    . THR B 1 32  ? 14.485  9.365   -29.406  1.00 103.41 ? 32  THR B CA    1 
ATOM   4301  C C     . THR B 1 32  ? 14.378  10.596  -28.491  1.00 114.58 ? 32  THR B C     1 
ATOM   4302  O O     . THR B 1 32  ? 14.093  11.691  -28.976  1.00 114.23 ? 32  THR B O     1 
ATOM   4303  C CB    . THR B 1 32  ? 15.489  8.280   -28.975  1.00 90.65  ? 32  THR B CB    1 
ATOM   4304  O OG1   . THR B 1 32  ? 16.805  8.823   -29.034  1.00 83.38  ? 32  THR B OG1   1 
ATOM   4305  C CG2   . THR B 1 32  ? 15.444  7.033   -29.832  1.00 85.68  ? 32  THR B CG2   1 
ATOM   4306  N N     . GLU B 1 33  ? 14.651  10.426  -27.184  1.00 120.89 ? 33  GLU B N     1 
ATOM   4307  C CA    . GLU B 1 33  ? 14.063  11.225  -26.110  1.00 119.75 ? 33  GLU B CA    1 
ATOM   4308  C C     . GLU B 1 33  ? 14.395  12.713  -26.238  1.00 116.41 ? 33  GLU B C     1 
ATOM   4309  O O     . GLU B 1 33  ? 15.382  13.072  -26.870  1.00 115.62 ? 33  GLU B O     1 
ATOM   4310  C CB    . GLU B 1 33  ? 14.556  10.691  -24.765  1.00 128.96 ? 33  GLU B CB    1 
ATOM   4311  C CG    . GLU B 1 33  ? 14.097  9.267   -24.489  1.00 128.82 ? 33  GLU B CG    1 
ATOM   4312  C CD    . GLU B 1 33  ? 14.972  8.483   -23.527  1.00 136.51 ? 33  GLU B CD    1 
ATOM   4313  O OE1   . GLU B 1 33  ? 16.107  8.138   -23.915  1.00 148.75 ? 33  GLU B OE1   1 
ATOM   4314  O OE2   . GLU B 1 33  ? 14.514  8.216   -22.402  1.00 118.75 ? 33  GLU B OE2   1 
ATOM   4315  N N     . ASP B 1 34  ? 13.543  13.569  -25.644  1.00 117.19 ? 34  ASP B N     1 
ATOM   4316  C CA    . ASP B 1 34  ? 13.737  15.018  -25.610  1.00 122.38 ? 34  ASP B CA    1 
ATOM   4317  C C     . ASP B 1 34  ? 13.445  15.606  -26.995  1.00 121.78 ? 34  ASP B C     1 
ATOM   4318  O O     . ASP B 1 34  ? 12.801  16.648  -27.128  1.00 104.80 ? 34  ASP B O     1 
ATOM   4319  C CB    . ASP B 1 34  ? 15.144  15.390  -25.115  1.00 128.09 ? 34  ASP B CB    1 
ATOM   4320  C CG    . ASP B 1 34  ? 15.303  16.815  -24.596  1.00 124.51 ? 34  ASP B CG    1 
ATOM   4321  O OD1   . ASP B 1 34  ? 14.862  17.082  -23.453  1.00 108.94 ? 34  ASP B OD1   1 
ATOM   4322  O OD2   . ASP B 1 34  ? 15.870  17.653  -25.338  1.00 117.61 ? 34  ASP B OD2   1 
ATOM   4323  N N     . LYS B 1 35  ? 13.932  14.925  -28.036  1.00 116.28 ? 35  LYS B N     1 
ATOM   4324  C CA    . LYS B 1 35  ? 13.547  15.221  -29.402  1.00 105.25 ? 35  LYS B CA    1 
ATOM   4325  C C     . LYS B 1 35  ? 12.163  14.642  -29.698  1.00 97.66  ? 35  LYS B C     1 
ATOM   4326  O O     . LYS B 1 35  ? 11.746  14.643  -30.848  1.00 87.76  ? 35  LYS B O     1 
ATOM   4327  C CB    . LYS B 1 35  ? 14.556  14.604  -30.370  1.00 104.79 ? 35  LYS B CB    1 
ATOM   4328  C CG    . LYS B 1 35  ? 16.017  14.937  -30.108  1.00 113.67 ? 35  LYS B CG    1 
ATOM   4329  C CD    . LYS B 1 35  ? 16.925  14.195  -31.061  1.00 120.86 ? 35  LYS B CD    1 
ATOM   4330  C CE    . LYS B 1 35  ? 18.140  14.990  -31.477  1.00 115.42 ? 35  LYS B CE    1 
ATOM   4331  N NZ    . LYS B 1 35  ? 18.494  14.688  -32.882  1.00 109.02 ? 35  LYS B NZ    1 
ATOM   4332  N N     . ILE B 1 36  ? 11.473  14.130  -28.665  1.00 105.10 ? 36  ILE B N     1 
ATOM   4333  C CA    . ILE B 1 36  ? 10.167  13.500  -28.809  1.00 99.79  ? 36  ILE B CA    1 
ATOM   4334  C C     . ILE B 1 36  ? 9.044   14.466  -28.402  1.00 97.82  ? 36  ILE B C     1 
ATOM   4335  O O     . ILE B 1 36  ? 7.876   14.183  -28.663  1.00 99.93  ? 36  ILE B O     1 
ATOM   4336  C CB    . ILE B 1 36  ? 10.117  12.194  -27.985  1.00 92.92  ? 36  ILE B CB    1 
ATOM   4337  C CG1   . ILE B 1 36  ? 9.143   11.162  -28.571  1.00 91.09  ? 36  ILE B CG1   1 
ATOM   4338  C CG2   . ILE B 1 36  ? 9.817   12.492  -26.517  1.00 98.18  ? 36  ILE B CG2   1 
ATOM   4339  C CD1   . ILE B 1 36  ? 9.655   10.419  -29.796  1.00 89.35  ? 36  ILE B CD1   1 
ATOM   4340  N N     . THR B 1 37  ? 9.375   15.606  -27.774  1.00 91.94  ? 37  THR B N     1 
ATOM   4341  C CA    . THR B 1 37  ? 8.356   16.436  -27.141  1.00 96.68  ? 37  THR B CA    1 
ATOM   4342  C C     . THR B 1 37  ? 7.509   17.166  -28.193  1.00 87.70  ? 37  THR B C     1 
ATOM   4343  O O     . THR B 1 37  ? 6.378   17.537  -27.892  1.00 82.20  ? 37  THR B O     1 
ATOM   4344  C CB    . THR B 1 37  ? 8.936   17.347  -26.039  1.00 93.44  ? 37  THR B CB    1 
ATOM   4345  O OG1   . THR B 1 37  ? 10.123  17.955  -26.546  1.00 88.05  ? 37  THR B OG1   1 
ATOM   4346  C CG2   . THR B 1 37  ? 9.242   16.621  -24.739  1.00 81.50  ? 37  THR B CG2   1 
ATOM   4347  N N     . PRO B 1 38  ? 7.951   17.381  -29.458  1.00 92.24  ? 38  PRO B N     1 
ATOM   4348  C CA    . PRO B 1 38  ? 7.025   17.839  -30.507  1.00 93.92  ? 38  PRO B CA    1 
ATOM   4349  C C     . PRO B 1 38  ? 5.857   16.895  -30.835  1.00 91.94  ? 38  PRO B C     1 
ATOM   4350  O O     . PRO B 1 38  ? 4.838   17.356  -31.350  1.00 79.27  ? 38  PRO B O     1 
ATOM   4351  C CB    . PRO B 1 38  ? 7.925   18.007  -31.747  1.00 92.79  ? 38  PRO B CB    1 
ATOM   4352  C CG    . PRO B 1 38  ? 9.324   18.177  -31.179  1.00 95.51  ? 38  PRO B CG    1 
ATOM   4353  C CD    . PRO B 1 38  ? 9.344   17.312  -29.935  1.00 91.93  ? 38  PRO B CD    1 
ATOM   4354  N N     . TYR B 1 39  ? 6.011   15.587  -30.531  1.00 86.49  ? 39  TYR B N     1 
ATOM   4355  C CA    . TYR B 1 39  ? 5.081   14.537  -30.936  1.00 83.84  ? 39  TYR B CA    1 
ATOM   4356  C C     . TYR B 1 39  ? 4.119   14.166  -29.810  1.00 82.63  ? 39  TYR B C     1 
ATOM   4357  O O     . TYR B 1 39  ? 3.288   13.282  -30.005  1.00 77.21  ? 39  TYR B O     1 
ATOM   4358  C CB    . TYR B 1 39  ? 5.819   13.266  -31.378  1.00 82.84  ? 39  TYR B CB    1 
ATOM   4359  C CG    . TYR B 1 39  ? 6.691   13.449  -32.595  1.00 87.01  ? 39  TYR B CG    1 
ATOM   4360  C CD1   . TYR B 1 39  ? 6.151   13.582  -33.863  1.00 86.31  ? 39  TYR B CD1   1 
ATOM   4361  C CD2   . TYR B 1 39  ? 8.062   13.555  -32.466  1.00 88.62  ? 39  TYR B CD2   1 
ATOM   4362  C CE1   . TYR B 1 39  ? 6.951   13.789  -34.973  1.00 90.65  ? 39  TYR B CE1   1 
ATOM   4363  C CE2   . TYR B 1 39  ? 8.876   13.771  -33.561  1.00 95.88  ? 39  TYR B CE2   1 
ATOM   4364  C CZ    . TYR B 1 39  ? 8.323   13.883  -34.820  1.00 94.94  ? 39  TYR B CZ    1 
ATOM   4365  O OH    . TYR B 1 39  ? 9.187   14.082  -35.870  1.00 92.97  ? 39  TYR B OH    1 
ATOM   4366  N N     . GLU B 1 40  ? 4.249   14.829  -28.651  1.00 78.59  ? 40  GLU B N     1 
ATOM   4367  C CA    . GLU B 1 40  ? 3.303   14.708  -27.552  1.00 88.27  ? 40  GLU B CA    1 
ATOM   4368  C C     . GLU B 1 40  ? 1.994   15.391  -27.946  1.00 84.89  ? 40  GLU B C     1 
ATOM   4369  O O     . GLU B 1 40  ? 1.949   16.112  -28.942  1.00 87.56  ? 40  GLU B O     1 
ATOM   4370  C CB    . GLU B 1 40  ? 3.836   15.378  -26.276  1.00 94.45  ? 40  GLU B CB    1 
ATOM   4371  C CG    . GLU B 1 40  ? 5.171   14.845  -25.778  1.00 88.42  ? 40  GLU B CG    1 
ATOM   4372  C CD    . GLU B 1 40  ? 5.174   13.449  -25.177  1.00 88.47  ? 40  GLU B CD    1 
ATOM   4373  O OE1   . GLU B 1 40  ? 4.076   12.851  -24.969  1.00 83.18  ? 40  GLU B OE1   1 
ATOM   4374  O OE2   . GLU B 1 40  ? 6.290   12.957  -24.921  1.00 90.74  ? 40  GLU B OE2   1 
ATOM   4375  N N     . ASP B 1 41  ? 0.938   15.168  -27.151  1.00 80.46  ? 41  ASP B N     1 
ATOM   4376  C CA    . ASP B 1 41  ? -0.309  15.900  -27.320  1.00 86.72  ? 41  ASP B CA    1 
ATOM   4377  C C     . ASP B 1 41  ? -0.078  17.357  -26.894  1.00 75.82  ? 41  ASP B C     1 
ATOM   4378  O O     . ASP B 1 41  ? 0.199   17.646  -25.728  1.00 63.48  ? 41  ASP B O     1 
ATOM   4379  C CB    . ASP B 1 41  ? -1.441  15.190  -26.560  1.00 93.72  ? 41  ASP B CB    1 
ATOM   4380  C CG    . ASP B 1 41  ? -2.832  15.827  -26.597  1.00 97.03  ? 41  ASP B CG    1 
ATOM   4381  O OD1   . ASP B 1 41  ? -3.096  16.749  -27.455  1.00 70.62  ? 41  ASP B OD1   1 
ATOM   4382  O OD2   . ASP B 1 41  ? -3.659  15.396  -25.739  1.00 99.69  ? 41  ASP B OD2   1 
ATOM   4383  N N     . PRO B 1 42  ? -0.191  18.345  -27.813  1.00 80.93  ? 42  PRO B N     1 
ATOM   4384  C CA    . PRO B 1 42  ? -0.080  19.749  -27.402  1.00 79.33  ? 42  PRO B CA    1 
ATOM   4385  C C     . PRO B 1 42  ? -1.124  20.176  -26.357  1.00 80.85  ? 42  PRO B C     1 
ATOM   4386  O O     . PRO B 1 42  ? -0.824  21.048  -25.536  1.00 75.98  ? 42  PRO B O     1 
ATOM   4387  C CB    . PRO B 1 42  ? -0.178  20.563  -28.709  1.00 72.79  ? 42  PRO B CB    1 
ATOM   4388  C CG    . PRO B 1 42  ? -0.552  19.568  -29.815  1.00 70.14  ? 42  PRO B CG    1 
ATOM   4389  C CD    . PRO B 1 42  ? -0.421  18.165  -29.261  1.00 74.08  ? 42  PRO B CD    1 
ATOM   4390  N N     . TYR B 1 43  ? -2.327  19.552  -26.375  1.00 85.52  ? 43  TYR B N     1 
ATOM   4391  C CA    . TYR B 1 43  ? -3.428  19.879  -25.461  1.00 88.54  ? 43  TYR B CA    1 
ATOM   4392  C C     . TYR B 1 43  ? -3.800  18.670  -24.582  1.00 82.04  ? 43  TYR B C     1 
ATOM   4393  O O     . TYR B 1 43  ? -4.798  17.983  -24.836  1.00 75.53  ? 43  TYR B O     1 
ATOM   4394  C CB    . TYR B 1 43  ? -4.675  20.396  -26.210  1.00 85.27  ? 43  TYR B CB    1 
ATOM   4395  C CG    . TYR B 1 43  ? -4.446  21.384  -27.334  1.00 74.44  ? 43  TYR B CG    1 
ATOM   4396  C CD1   . TYR B 1 43  ? -3.495  22.396  -27.243  1.00 78.98  ? 43  TYR B CD1   1 
ATOM   4397  C CD2   . TYR B 1 43  ? -5.212  21.327  -28.486  1.00 64.64  ? 43  TYR B CD2   1 
ATOM   4398  C CE1   . TYR B 1 43  ? -3.279  23.287  -28.284  1.00 80.68  ? 43  TYR B CE1   1 
ATOM   4399  C CE2   . TYR B 1 43  ? -5.007  22.205  -29.537  1.00 66.24  ? 43  TYR B CE2   1 
ATOM   4400  C CZ    . TYR B 1 43  ? -4.038  23.188  -29.439  1.00 80.11  ? 43  TYR B CZ    1 
ATOM   4401  O OH    . TYR B 1 43  ? -3.857  24.075  -30.475  1.00 75.48  ? 43  TYR B OH    1 
ATOM   4402  N N     . THR B 1 44  ? -3.011  18.460  -23.515  1.00 74.18  ? 44  THR B N     1 
ATOM   4403  C CA    . THR B 1 44  ? -3.173  17.367  -22.561  1.00 73.80  ? 44  THR B CA    1 
ATOM   4404  C C     . THR B 1 44  ? -4.583  17.357  -21.956  1.00 74.75  ? 44  THR B C     1 
ATOM   4405  O O     . THR B 1 44  ? -5.134  18.424  -21.664  1.00 69.40  ? 44  THR B O     1 
ATOM   4406  C CB    . THR B 1 44  ? -2.123  17.510  -21.445  1.00 71.23  ? 44  THR B CB    1 
ATOM   4407  O OG1   . THR B 1 44  ? -0.974  18.115  -22.045  1.00 68.87  ? 44  THR B OG1   1 
ATOM   4408  C CG2   . THR B 1 44  ? -1.772  16.204  -20.753  1.00 62.31  ? 44  THR B CG2   1 
ATOM   4409  N N     . ILE B 1 45  ? -5.161  16.146  -21.796  1.00 77.53  ? 45  ILE B N     1 
ATOM   4410  C CA    . ILE B 1 45  ? -6.419  15.923  -21.076  1.00 82.54  ? 45  ILE B CA    1 
ATOM   4411  C C     . ILE B 1 45  ? -6.193  14.944  -19.914  1.00 76.19  ? 45  ILE B C     1 
ATOM   4412  O O     . ILE B 1 45  ? -6.862  15.038  -18.884  1.00 69.28  ? 45  ILE B O     1 
ATOM   4413  C CB    . ILE B 1 45  ? -7.552  15.415  -22.007  1.00 80.77  ? 45  ILE B CB    1 
ATOM   4414  C CG1   . ILE B 1 45  ? -7.706  16.241  -23.287  1.00 78.58  ? 45  ILE B CG1   1 
ATOM   4415  C CG2   . ILE B 1 45  ? -8.879  15.343  -21.259  1.00 79.32  ? 45  ILE B CG2   1 
ATOM   4416  C CD1   . ILE B 1 45  ? -8.462  15.522  -24.384  1.00 78.09  ? 45  ILE B CD1   1 
ATOM   4417  N N     . SER B 1 46  ? -5.278  13.983  -20.122  1.00 77.37  ? 46  SER B N     1 
ATOM   4418  C CA    . SER B 1 46  ? -4.914  12.960  -19.155  1.00 77.69  ? 46  SER B CA    1 
ATOM   4419  C C     . SER B 1 46  ? -4.085  13.566  -18.018  1.00 85.68  ? 46  SER B C     1 
ATOM   4420  O O     . SER B 1 46  ? -3.134  14.310  -18.272  1.00 96.77  ? 46  SER B O     1 
ATOM   4421  C CB    . SER B 1 46  ? -4.149  11.852  -19.871  1.00 82.67  ? 46  SER B CB    1 
ATOM   4422  O OG    . SER B 1 46  ? -3.988  10.702  -19.051  1.00 80.15  ? 46  SER B OG    1 
ATOM   4423  N N     . ASN B 1 47  ? -4.439  13.216  -16.769  1.00 81.56  ? 47  ASN B N     1 
ATOM   4424  C CA    . ASN B 1 47  ? -3.685  13.575  -15.574  1.00 76.84  ? 47  ASN B CA    1 
ATOM   4425  C C     . ASN B 1 47  ? -2.645  12.501  -15.224  1.00 75.63  ? 47  ASN B C     1 
ATOM   4426  O O     . ASN B 1 47  ? -1.675  12.773  -14.512  1.00 79.86  ? 47  ASN B O     1 
ATOM   4427  C CB    . ASN B 1 47  ? -4.630  13.849  -14.398  1.00 73.16  ? 47  ASN B CB    1 
ATOM   4428  C CG    . ASN B 1 47  ? -5.139  15.275  -14.371  1.00 67.03  ? 47  ASN B CG    1 
ATOM   4429  O OD1   . ASN B 1 47  ? -4.402  16.202  -14.687  1.00 76.66  ? 47  ASN B OD1   1 
ATOM   4430  N ND2   . ASN B 1 47  ? -6.386  15.478  -13.986  1.00 62.03  ? 47  ASN B ND2   1 
ATOM   4431  N N     . ASP B 1 48  ? -2.870  11.275  -15.708  1.00 77.27  ? 48  ASP B N     1 
ATOM   4432  C CA    . ASP B 1 48  ? -1.873  10.219  -15.682  1.00 80.24  ? 48  ASP B CA    1 
ATOM   4433  C C     . ASP B 1 48  ? -0.959  10.410  -16.882  1.00 81.78  ? 48  ASP B C     1 
ATOM   4434  O O     . ASP B 1 48  ? -1.443  10.385  -18.013  1.00 79.80  ? 48  ASP B O     1 
ATOM   4435  C CB    . ASP B 1 48  ? -2.509  8.824   -15.752  1.00 84.59  ? 48  ASP B CB    1 
ATOM   4436  C CG    . ASP B 1 48  ? -1.519  7.681   -15.947  1.00 89.62  ? 48  ASP B CG    1 
ATOM   4437  O OD1   . ASP B 1 48  ? -0.315  7.868   -15.660  1.00 89.40  ? 48  ASP B OD1   1 
ATOM   4438  O OD2   . ASP B 1 48  ? -1.947  6.612   -16.417  1.00 94.96  ? 48  ASP B OD2   1 
ATOM   4439  N N     . GLU B 1 49  ? 0.356   10.501  -16.607  1.00 89.86  ? 49  GLU B N     1 
ATOM   4440  C CA    . GLU B 1 49  ? 1.370   10.858  -17.590  1.00 84.50  ? 49  GLU B CA    1 
ATOM   4441  C C     . GLU B 1 49  ? 1.964   9.636   -18.288  1.00 80.73  ? 49  GLU B C     1 
ATOM   4442  O O     . GLU B 1 49  ? 3.012   9.757   -18.907  1.00 80.99  ? 49  GLU B O     1 
ATOM   4443  C CB    . GLU B 1 49  ? 2.507   11.616  -16.909  1.00 90.11  ? 49  GLU B CB    1 
ATOM   4444  C CG    . GLU B 1 49  ? 2.071   12.933  -16.295  1.00 106.63 ? 49  GLU B CG    1 
ATOM   4445  C CD    . GLU B 1 49  ? 3.238   13.833  -15.929  1.00 108.13 ? 49  GLU B CD    1 
ATOM   4446  O OE1   . GLU B 1 49  ? 3.890   14.346  -16.868  1.00 97.55  ? 49  GLU B OE1   1 
ATOM   4447  O OE2   . GLU B 1 49  ? 3.513   13.987  -14.714  1.00 95.41  ? 49  GLU B OE2   1 
ATOM   4448  N N     . THR B 1 50  ? 1.298   8.477   -18.206  1.00 91.42  ? 50  THR B N     1 
ATOM   4449  C CA    . THR B 1 50  ? 1.791   7.244   -18.806  1.00 91.06  ? 50  THR B CA    1 
ATOM   4450  C C     . THR B 1 50  ? 0.992   6.906   -20.073  1.00 88.50  ? 50  THR B C     1 
ATOM   4451  O O     . THR B 1 50  ? 1.300   5.911   -20.720  1.00 83.85  ? 50  THR B O     1 
ATOM   4452  C CB    . THR B 1 50  ? 1.780   6.079   -17.787  1.00 99.37  ? 50  THR B CB    1 
ATOM   4453  O OG1   . THR B 1 50  ? 0.462   5.853   -17.270  1.00 88.21  ? 50  THR B OG1   1 
ATOM   4454  C CG2   . THR B 1 50  ? 2.722   6.282   -16.615  1.00 90.54  ? 50  THR B CG2   1 
ATOM   4455  N N     . GLU B 1 51  ? -0.024  7.719   -20.431  1.00 91.84  ? 51  GLU B N     1 
ATOM   4456  C CA    . GLU B 1 51  ? -0.941  7.406   -21.526  1.00 89.06  ? 51  GLU B CA    1 
ATOM   4457  C C     . GLU B 1 51  ? -0.654  8.312   -22.719  1.00 77.04  ? 51  GLU B C     1 
ATOM   4458  O O     . GLU B 1 51  ? -0.357  9.479   -22.499  1.00 71.53  ? 51  GLU B O     1 
ATOM   4459  C CB    . GLU B 1 51  ? -2.397  7.640   -21.117  1.00 96.58  ? 51  GLU B CB    1 
ATOM   4460  C CG    . GLU B 1 51  ? -2.823  6.949   -19.826  1.00 95.75  ? 51  GLU B CG    1 
ATOM   4461  C CD    . GLU B 1 51  ? -4.266  7.210   -19.411  1.00 90.46  ? 51  GLU B CD    1 
ATOM   4462  O OE1   . GLU B 1 51  ? -4.947  7.985   -20.106  1.00 93.35  ? 51  GLU B OE1   1 
ATOM   4463  O OE2   . GLU B 1 51  ? -4.713  6.638   -18.397  1.00 90.70  ? 51  GLU B OE2   1 
ATOM   4464  N N     . HIS B 1 52  ? -0.769  7.778   -23.953  1.00 72.98  ? 52  HIS B N     1 
ATOM   4465  C CA    . HIS B 1 52  ? -0.547  8.528   -25.192  1.00 72.12  ? 52  HIS B CA    1 
ATOM   4466  C C     . HIS B 1 52  ? 0.863   9.137   -25.292  1.00 76.26  ? 52  HIS B C     1 
ATOM   4467  O O     . HIS B 1 52  ? 0.998   10.310  -25.671  1.00 68.00  ? 52  HIS B O     1 
ATOM   4468  C CB    . HIS B 1 52  ? -1.605  9.629   -25.356  1.00 72.08  ? 52  HIS B CB    1 
ATOM   4469  C CG    . HIS B 1 52  ? -2.950  9.198   -24.898  1.00 86.82  ? 52  HIS B CG    1 
ATOM   4470  N ND1   . HIS B 1 52  ? -3.715  8.276   -25.577  1.00 100.89 ? 52  HIS B ND1   1 
ATOM   4471  C CD2   . HIS B 1 52  ? -3.651  9.534   -23.809  1.00 104.39 ? 52  HIS B CD2   1 
ATOM   4472  C CE1   . HIS B 1 52  ? -4.847  8.073   -24.916  1.00 106.62 ? 52  HIS B CE1   1 
ATOM   4473  N NE2   . HIS B 1 52  ? -4.830  8.827   -23.836  1.00 114.48 ? 52  HIS B NE2   1 
ATOM   4474  N N     . ARG B 1 53  ? 1.899   8.317   -24.993  1.00 84.26  ? 53  ARG B N     1 
ATOM   4475  C CA    . ARG B 1 53  ? 3.315   8.708   -24.938  1.00 86.00  ? 53  ARG B CA    1 
ATOM   4476  C C     . ARG B 1 53  ? 4.114   7.993   -26.031  1.00 75.25  ? 53  ARG B C     1 
ATOM   4477  O O     . ARG B 1 53  ? 4.305   6.779   -25.970  1.00 78.32  ? 53  ARG B O     1 
ATOM   4478  C CB    . ARG B 1 53  ? 3.994   8.329   -23.606  1.00 82.95  ? 53  ARG B CB    1 
ATOM   4479  C CG    . ARG B 1 53  ? 3.227   8.700   -22.346  1.00 83.05  ? 53  ARG B CG    1 
ATOM   4480  C CD    . ARG B 1 53  ? 2.813   10.163  -22.318  1.00 98.39  ? 53  ARG B CD    1 
ATOM   4481  N NE    . ARG B 1 53  ? 3.930   11.085  -22.475  1.00 100.01 ? 53  ARG B NE    1 
ATOM   4482  C CZ    . ARG B 1 53  ? 4.830   11.362  -21.536  1.00 96.03  ? 53  ARG B CZ    1 
ATOM   4483  N NH1   . ARG B 1 53  ? 4.649   10.979  -20.283  1.00 82.35  ? 53  ARG B NH1   1 
ATOM   4484  N NH2   . ARG B 1 53  ? 5.905   12.060  -21.856  1.00 102.35 ? 53  ARG B NH2   1 
ATOM   4485  N N     . PRO B 1 54  ? 4.640   8.703   -27.053  1.00 73.65  ? 54  PRO B N     1 
ATOM   4486  C CA    . PRO B 1 54  ? 5.419   8.046   -28.102  1.00 71.86  ? 54  PRO B CA    1 
ATOM   4487  C C     . PRO B 1 54  ? 6.798   7.674   -27.568  1.00 67.48  ? 54  PRO B C     1 
ATOM   4488  O O     . PRO B 1 54  ? 7.275   8.322   -26.647  1.00 72.90  ? 54  PRO B O     1 
ATOM   4489  C CB    . PRO B 1 54  ? 5.461   9.062   -29.255  1.00 68.98  ? 54  PRO B CB    1 
ATOM   4490  C CG    . PRO B 1 54  ? 5.123   10.418  -28.626  1.00 72.92  ? 54  PRO B CG    1 
ATOM   4491  C CD    . PRO B 1 54  ? 4.486   10.149  -27.275  1.00 75.23  ? 54  PRO B CD    1 
ATOM   4492  N N     . TYR B 1 55  ? 7.385   6.603   -28.123  1.00 73.15  ? 55  TYR B N     1 
ATOM   4493  C CA    . TYR B 1 55  ? 8.689   6.105   -27.712  1.00 76.32  ? 55  TYR B CA    1 
ATOM   4494  C C     . TYR B 1 55  ? 9.786   6.647   -28.622  1.00 81.59  ? 55  TYR B C     1 
ATOM   4495  O O     . TYR B 1 55  ? 10.824  7.089   -28.146  1.00 92.92  ? 55  TYR B O     1 
ATOM   4496  C CB    . TYR B 1 55  ? 8.759   4.578   -27.764  1.00 81.22  ? 55  TYR B CB    1 
ATOM   4497  C CG    . TYR B 1 55  ? 9.978   3.995   -27.090  1.00 92.07  ? 55  TYR B CG    1 
ATOM   4498  C CD1   . TYR B 1 55  ? 10.028  3.832   -25.708  1.00 96.60  ? 55  TYR B CD1   1 
ATOM   4499  C CD2   . TYR B 1 55  ? 11.100  3.634   -27.825  1.00 96.26  ? 55  TYR B CD2   1 
ATOM   4500  C CE1   . TYR B 1 55  ? 11.150  3.311   -25.078  1.00 99.89  ? 55  TYR B CE1   1 
ATOM   4501  C CE2   . TYR B 1 55  ? 12.230  3.115   -27.212  1.00 102.49 ? 55  TYR B CE2   1 
ATOM   4502  C CZ    . TYR B 1 55  ? 12.255  2.954   -25.836  1.00 102.94 ? 55  TYR B CZ    1 
ATOM   4503  O OH    . TYR B 1 55  ? 13.383  2.457   -25.237  1.00 106.09 ? 55  TYR B OH    1 
ATOM   4504  N N     . ALA B 1 56  ? 9.573   6.557   -29.938  1.00 82.31  ? 56  ALA B N     1 
ATOM   4505  C CA    . ALA B 1 56  ? 10.530  7.074   -30.902  1.00 71.05  ? 56  ALA B CA    1 
ATOM   4506  C C     . ALA B 1 56  ? 9.788   7.542   -32.145  1.00 70.55  ? 56  ALA B C     1 
ATOM   4507  O O     . ALA B 1 56  ? 8.613   7.239   -32.316  1.00 83.51  ? 56  ALA B O     1 
ATOM   4508  C CB    . ALA B 1 56  ? 11.537  6.007   -31.239  1.00 71.16  ? 56  ALA B CB    1 
ATOM   4509  N N     . ALA B 1 57  ? 10.481  8.293   -32.999  1.00 64.17  ? 57  ALA B N     1 
ATOM   4510  C CA    . ALA B 1 57  ? 9.928   8.695   -34.277  1.00 61.10  ? 57  ALA B CA    1 
ATOM   4511  C C     . ALA B 1 57  ? 10.953  8.407   -35.362  1.00 60.19  ? 57  ALA B C     1 
ATOM   4512  O O     . ALA B 1 57  ? 12.137  8.565   -35.107  1.00 69.54  ? 57  ALA B O     1 
ATOM   4513  C CB    . ALA B 1 57  ? 9.546   10.152  -34.237  1.00 60.32  ? 57  ALA B CB    1 
ATOM   4514  N N     . VAL B 1 58  ? 10.487  7.947   -36.532  1.00 55.29  ? 58  VAL B N     1 
ATOM   4515  C CA    . VAL B 1 58  ? 11.319  7.704   -37.704  1.00 56.43  ? 58  VAL B CA    1 
ATOM   4516  C C     . VAL B 1 58  ? 10.649  8.440   -38.856  1.00 64.25  ? 58  VAL B C     1 
ATOM   4517  O O     . VAL B 1 58  ? 9.432   8.604   -38.841  1.00 71.87  ? 58  VAL B O     1 
ATOM   4518  C CB    . VAL B 1 58  ? 11.527  6.203   -38.014  1.00 59.59  ? 58  VAL B CB    1 
ATOM   4519  C CG1   . VAL B 1 58  ? 10.318  5.358   -37.674  1.00 70.65  ? 58  VAL B CG1   1 
ATOM   4520  C CG2   . VAL B 1 58  ? 11.920  5.937   -39.458  1.00 57.64  ? 58  VAL B CG2   1 
ATOM   4521  N N     . ALA B 1 59  ? 11.442  8.925   -39.821  1.00 57.54  ? 59  ALA B N     1 
ATOM   4522  C CA    . ALA B 1 59  ? 10.955  9.964   -40.707  1.00 52.79  ? 59  ALA B CA    1 
ATOM   4523  C C     . ALA B 1 59  ? 11.510  9.734   -42.100  1.00 53.86  ? 59  ALA B C     1 
ATOM   4524  O O     . ALA B 1 59  ? 12.496  10.356  -42.463  1.00 61.96  ? 59  ALA B O     1 
ATOM   4525  C CB    . ALA B 1 59  ? 11.340  11.318  -40.175  1.00 47.34  ? 59  ALA B CB    1 
ATOM   4526  N N     . PRO B 1 60  ? 10.876  8.863   -42.912  1.00 55.85  ? 60  PRO B N     1 
ATOM   4527  C CA    . PRO B 1 60  ? 11.403  8.485   -44.228  1.00 58.75  ? 60  PRO B CA    1 
ATOM   4528  C C     . PRO B 1 60  ? 11.175  9.514   -45.331  1.00 54.29  ? 60  PRO B C     1 
ATOM   4529  O O     . PRO B 1 60  ? 10.472  10.503  -45.130  1.00 50.04  ? 60  PRO B O     1 
ATOM   4530  C CB    . PRO B 1 60  ? 10.659  7.193   -44.583  1.00 60.44  ? 60  PRO B CB    1 
ATOM   4531  C CG    . PRO B 1 60  ? 9.379   7.240   -43.756  1.00 66.28  ? 60  PRO B CG    1 
ATOM   4532  C CD    . PRO B 1 60  ? 9.624   8.170   -42.583  1.00 59.82  ? 60  PRO B CD    1 
ATOM   4533  N N     . ALA B 1 61  ? 11.809  9.268   -46.485  1.00 61.66  ? 61  ALA B N     1 
ATOM   4534  C CA    . ALA B 1 61  ? 11.845  10.243  -47.573  1.00 71.30  ? 61  ALA B CA    1 
ATOM   4535  C C     . ALA B 1 61  ? 11.203  9.671   -48.832  1.00 65.66  ? 61  ALA B C     1 
ATOM   4536  O O     . ALA B 1 61  ? 11.258  10.300  -49.883  1.00 62.57  ? 61  ALA B O     1 
ATOM   4537  C CB    . ALA B 1 61  ? 13.267  10.685  -47.860  1.00 65.79  ? 61  ALA B CB    1 
ATOM   4538  N N     . SER B 1 62  ? 10.581  8.494   -48.723  1.00 64.85  ? 62  SER B N     1 
ATOM   4539  C CA    . SER B 1 62  ? 10.112  7.814   -49.913  1.00 63.87  ? 62  SER B CA    1 
ATOM   4540  C C     . SER B 1 62  ? 9.306   6.571   -49.552  1.00 67.81  ? 62  SER B C     1 
ATOM   4541  O O     . SER B 1 62  ? 9.402   6.029   -48.450  1.00 62.33  ? 62  SER B O     1 
ATOM   4542  C CB    . SER B 1 62  ? 11.270  7.428   -50.798  1.00 64.13  ? 62  SER B CB    1 
ATOM   4543  O OG    . SER B 1 62  ? 11.925  6.261   -50.309  1.00 65.71  ? 62  SER B OG    1 
ATOM   4544  N N     . THR B 1 63  ? 8.599   6.073   -50.567  1.00 61.69  ? 63  THR B N     1 
ATOM   4545  C CA    . THR B 1 63  ? 7.676   4.981   -50.408  1.00 54.23  ? 63  THR B CA    1 
ATOM   4546  C C     . THR B 1 63  ? 8.437   3.708   -50.075  1.00 64.29  ? 63  THR B C     1 
ATOM   4547  O O     . THR B 1 63  ? 7.930   2.901   -49.297  1.00 75.73  ? 63  THR B O     1 
ATOM   4548  C CB    . THR B 1 63  ? 6.806   4.861   -51.657  1.00 56.56  ? 63  THR B CB    1 
ATOM   4549  O OG1   . THR B 1 63  ? 5.972   6.023   -51.674  1.00 62.38  ? 63  THR B OG1   1 
ATOM   4550  C CG2   . THR B 1 63  ? 5.965   3.605   -51.694  1.00 55.42  ? 63  THR B CG2   1 
ATOM   4551  N N     . GLU B 1 64  ? 9.645   3.537   -50.636  1.00 67.36  ? 64  GLU B N     1 
ATOM   4552  C CA    . GLU B 1 64  ? 10.400  2.302   -50.436  1.00 62.69  ? 64  GLU B CA    1 
ATOM   4553  C C     . GLU B 1 64  ? 10.967  2.286   -49.016  1.00 57.37  ? 64  GLU B C     1 
ATOM   4554  O O     . GLU B 1 64  ? 11.055  1.232   -48.397  1.00 56.59  ? 64  GLU B O     1 
ATOM   4555  C CB    . GLU B 1 64  ? 11.502  2.109   -51.480  1.00 68.77  ? 64  GLU B CB    1 
ATOM   4556  C CG    . GLU B 1 64  ? 11.016  2.204   -52.924  1.00 85.79  ? 64  GLU B CG    1 
ATOM   4557  C CD    . GLU B 1 64  ? 10.460  3.561   -53.348  1.00 94.36  ? 64  GLU B CD    1 
ATOM   4558  O OE1   . GLU B 1 64  ? 11.075  4.607   -52.998  1.00 104.84 ? 64  GLU B OE1   1 
ATOM   4559  O OE2   . GLU B 1 64  ? 9.410   3.578   -54.031  1.00 84.23  ? 64  GLU B OE2   1 
ATOM   4560  N N     . GLU B 1 65  ? 11.286  3.460   -48.462  1.00 52.71  ? 65  GLU B N     1 
ATOM   4561  C CA    . GLU B 1 65  ? 11.739  3.527   -47.084  1.00 57.94  ? 65  GLU B CA    1 
ATOM   4562  C C     . GLU B 1 65  ? 10.583  3.165   -46.141  1.00 64.17  ? 65  GLU B C     1 
ATOM   4563  O O     . GLU B 1 65  ? 10.789  2.443   -45.153  1.00 57.52  ? 65  GLU B O     1 
ATOM   4564  C CB    . GLU B 1 65  ? 12.384  4.890   -46.814  1.00 67.78  ? 65  GLU B CB    1 
ATOM   4565  C CG    . GLU B 1 65  ? 13.704  5.093   -47.565  1.00 73.80  ? 65  GLU B CG    1 
ATOM   4566  C CD    . GLU B 1 65  ? 14.458  6.417   -47.414  1.00 77.30  ? 65  GLU B CD    1 
ATOM   4567  O OE1   . GLU B 1 65  ? 14.016  7.295   -46.616  1.00 66.25  ? 65  GLU B OE1   1 
ATOM   4568  O OE2   . GLU B 1 65  ? 15.506  6.571   -48.113  1.00 67.00  ? 65  GLU B OE2   1 
ATOM   4569  N N     . VAL B 1 66  ? 9.357   3.619   -46.469  1.00 60.35  ? 66  VAL B N     1 
ATOM   4570  C CA    . VAL B 1 66  ? 8.176   3.253   -45.693  1.00 54.65  ? 66  VAL B CA    1 
ATOM   4571  C C     . VAL B 1 66  ? 8.006   1.735   -45.696  1.00 57.06  ? 66  VAL B C     1 
ATOM   4572  O O     . VAL B 1 66  ? 7.725   1.139   -44.646  1.00 58.41  ? 66  VAL B O     1 
ATOM   4573  C CB    . VAL B 1 66  ? 6.899   3.964   -46.184  1.00 58.42  ? 66  VAL B CB    1 
ATOM   4574  C CG1   . VAL B 1 66  ? 5.640   3.373   -45.555  1.00 61.95  ? 66  VAL B CG1   1 
ATOM   4575  C CG2   . VAL B 1 66  ? 6.949   5.465   -45.929  1.00 53.44  ? 66  VAL B CG2   1 
ATOM   4576  N N     . GLN B 1 67  ? 8.205   1.124   -46.871  1.00 54.49  ? 67  GLN B N     1 
ATOM   4577  C CA    . GLN B 1 67  ? 8.037   -0.310  -47.031  1.00 58.45  ? 67  GLN B CA    1 
ATOM   4578  C C     . GLN B 1 67  ? 9.056   -1.058  -46.176  1.00 67.52  ? 67  GLN B C     1 
ATOM   4579  O O     . GLN B 1 67  ? 8.711   -2.057  -45.543  1.00 74.41  ? 67  GLN B O     1 
ATOM   4580  C CB    . GLN B 1 67  ? 8.183   -0.718  -48.497  1.00 59.88  ? 67  GLN B CB    1 
ATOM   4581  C CG    . GLN B 1 67  ? 7.168   -0.065  -49.417  1.00 60.68  ? 67  GLN B CG    1 
ATOM   4582  C CD    . GLN B 1 67  ? 7.295   -0.512  -50.857  1.00 62.30  ? 67  GLN B CD    1 
ATOM   4583  O OE1   . GLN B 1 67  ? 7.701   0.251   -51.737  1.00 68.44  ? 67  GLN B OE1   1 
ATOM   4584  N NE2   . GLN B 1 67  ? 6.935   -1.758  -51.111  1.00 54.47  ? 67  GLN B NE2   1 
ATOM   4585  N N     . GLU B 1 68  ? 10.308  -0.569  -46.164  1.00 75.92  ? 68  GLU B N     1 
ATOM   4586  C CA    . GLU B 1 68  ? 11.384  -1.182  -45.390  1.00 80.98  ? 68  GLU B CA    1 
ATOM   4587  C C     . GLU B 1 68  ? 11.031  -1.133  -43.896  1.00 73.86  ? 68  GLU B C     1 
ATOM   4588  O O     . GLU B 1 68  ? 11.049  -2.144  -43.184  1.00 62.92  ? 68  GLU B O     1 
ATOM   4589  C CB    . GLU B 1 68  ? 12.704  -0.449  -45.667  1.00 92.86  ? 68  GLU B CB    1 
ATOM   4590  C CG    . GLU B 1 68  ? 13.303  -0.645  -47.062  1.00 96.05  ? 68  GLU B CG    1 
ATOM   4591  C CD    . GLU B 1 68  ? 14.390  -1.707  -47.192  1.00 108.27 ? 68  GLU B CD    1 
ATOM   4592  O OE1   . GLU B 1 68  ? 14.602  -2.482  -46.224  1.00 102.40 ? 68  GLU B OE1   1 
ATOM   4593  O OE2   . GLU B 1 68  ? 15.038  -1.755  -48.263  1.00 112.39 ? 68  GLU B OE2   1 
ATOM   4594  N N     . ILE B 1 69  ? 10.659  0.068   -43.442  1.00 63.66  ? 69  ILE B N     1 
ATOM   4595  C CA    . ILE B 1 69  ? 10.295  0.292   -42.054  1.00 63.01  ? 69  ILE B CA    1 
ATOM   4596  C C     . ILE B 1 69  ? 9.237   -0.724  -41.644  1.00 58.21  ? 69  ILE B C     1 
ATOM   4597  O O     . ILE B 1 69  ? 9.371   -1.363  -40.611  1.00 54.88  ? 69  ILE B O     1 
ATOM   4598  C CB    . ILE B 1 69  ? 9.824   1.747   -41.855  1.00 56.17  ? 69  ILE B CB    1 
ATOM   4599  C CG1   . ILE B 1 69  ? 10.956  2.744   -42.101  1.00 51.85  ? 69  ILE B CG1   1 
ATOM   4600  C CG2   . ILE B 1 69  ? 9.207   1.941   -40.485  1.00 50.46  ? 69  ILE B CG2   1 
ATOM   4601  C CD1   . ILE B 1 69  ? 10.488  4.148   -42.392  1.00 56.29  ? 69  ILE B CD1   1 
ATOM   4602  N N     . VAL B 1 70  ? 8.223   -0.906  -42.490  1.00 53.35  ? 70  VAL B N     1 
ATOM   4603  C CA    . VAL B 1 70  ? 7.090   -1.735  -42.127  1.00 54.37  ? 70  VAL B CA    1 
ATOM   4604  C C     . VAL B 1 70  ? 7.504   -3.203  -42.047  1.00 53.41  ? 70  VAL B C     1 
ATOM   4605  O O     . VAL B 1 70  ? 7.023   -3.957  -41.185  1.00 53.66  ? 70  VAL B O     1 
ATOM   4606  C CB    . VAL B 1 70  ? 5.927   -1.508  -43.113  1.00 54.20  ? 70  VAL B CB    1 
ATOM   4607  C CG1   . VAL B 1 70  ? 4.845   -2.580  -43.008  1.00 49.60  ? 70  VAL B CG1   1 
ATOM   4608  C CG2   . VAL B 1 70  ? 5.335   -0.108  -42.956  1.00 49.23  ? 70  VAL B CG2   1 
ATOM   4609  N N     . ARG B 1 71  ? 8.356   -3.636  -42.978  1.00 55.36  ? 71  ARG B N     1 
ATOM   4610  C CA    . ARG B 1 71  ? 8.786   -5.024  -42.976  1.00 52.70  ? 71  ARG B CA    1 
ATOM   4611  C C     . ARG B 1 71  ? 9.563   -5.302  -41.688  1.00 59.26  ? 71  ARG B C     1 
ATOM   4612  O O     . ARG B 1 71  ? 9.438   -6.364  -41.075  1.00 54.32  ? 71  ARG B O     1 
ATOM   4613  C CB    . ARG B 1 71  ? 9.665   -5.314  -44.183  1.00 57.99  ? 71  ARG B CB    1 
ATOM   4614  C CG    . ARG B 1 71  ? 8.957   -5.280  -45.524  1.00 66.58  ? 71  ARG B CG    1 
ATOM   4615  C CD    . ARG B 1 71  ? 9.788   -6.085  -46.515  1.00 78.40  ? 71  ARG B CD    1 
ATOM   4616  N NE    . ARG B 1 71  ? 9.463   -5.831  -47.911  1.00 81.49  ? 71  ARG B NE    1 
ATOM   4617  C CZ    . ARG B 1 71  ? 9.781   -4.731  -48.585  1.00 68.53  ? 71  ARG B CZ    1 
ATOM   4618  N NH1   . ARG B 1 71  ? 10.611  -3.837  -48.075  1.00 62.01  ? 71  ARG B NH1   1 
ATOM   4619  N NH2   . ARG B 1 71  ? 9.270   -4.546  -49.789  1.00 71.52  ? 71  ARG B NH2   1 
ATOM   4620  N N     . VAL B 1 72  ? 10.349  -4.313  -41.257  1.00 56.05  ? 72  VAL B N     1 
ATOM   4621  C CA    . VAL B 1 72  ? 11.116  -4.439  -40.033  1.00 59.62  ? 72  VAL B CA    1 
ATOM   4622  C C     . VAL B 1 72  ? 10.188  -4.456  -38.819  1.00 63.39  ? 72  VAL B C     1 
ATOM   4623  O O     . VAL B 1 72  ? 10.300  -5.345  -37.968  1.00 69.31  ? 72  VAL B O     1 
ATOM   4624  C CB    . VAL B 1 72  ? 12.162  -3.316  -39.953  1.00 64.94  ? 72  VAL B CB    1 
ATOM   4625  C CG1   . VAL B 1 72  ? 12.824  -3.244  -38.590  1.00 64.37  ? 72  VAL B CG1   1 
ATOM   4626  C CG2   . VAL B 1 72  ? 13.195  -3.477  -41.063  1.00 71.49  ? 72  VAL B CG2   1 
ATOM   4627  N N     . ALA B 1 73  ? 9.287   -3.462  -38.737  1.00 65.53  ? 73  ALA B N     1 
ATOM   4628  C CA    . ALA B 1 73  ? 8.282   -3.408  -37.683  1.00 62.87  ? 73  ALA B CA    1 
ATOM   4629  C C     . ALA B 1 73  ? 7.632   -4.781  -37.521  1.00 59.13  ? 73  ALA B C     1 
ATOM   4630  O O     . ALA B 1 73  ? 7.417   -5.246  -36.397  1.00 52.23  ? 73  ALA B O     1 
ATOM   4631  C CB    . ALA B 1 73  ? 7.250   -2.353  -37.995  1.00 61.38  ? 73  ALA B CB    1 
ATOM   4632  N N     . ASN B 1 74  ? 7.348   -5.428  -38.661  1.00 53.55  ? 74  ASN B N     1 
ATOM   4633  C CA    . ASN B 1 74  ? 6.844   -6.791  -38.649  1.00 63.43  ? 74  ASN B CA    1 
ATOM   4634  C C     . ASN B 1 74  ? 7.836   -7.710  -37.949  1.00 65.04  ? 74  ASN B C     1 
ATOM   4635  O O     . ASN B 1 74  ? 7.461   -8.410  -37.020  1.00 61.77  ? 74  ASN B O     1 
ATOM   4636  C CB    . ASN B 1 74  ? 6.520   -7.308  -40.054  1.00 65.09  ? 74  ASN B CB    1 
ATOM   4637  C CG    . ASN B 1 74  ? 5.142   -6.877  -40.489  1.00 60.77  ? 74  ASN B CG    1 
ATOM   4638  O OD1   . ASN B 1 74  ? 4.155   -7.345  -39.922  1.00 50.50  ? 74  ASN B OD1   1 
ATOM   4639  N ND2   . ASN B 1 74  ? 5.082   -5.943  -41.425  1.00 62.69  ? 74  ASN B ND2   1 
ATOM   4640  N N     . GLU B 1 75  ? 9.100   -7.657  -38.386  1.00 76.50  ? 75  GLU B N     1 
ATOM   4641  C CA    . GLU B 1 75  ? 10.113  -8.608  -37.971  1.00 79.67  ? 75  GLU B CA    1 
ATOM   4642  C C     . GLU B 1 75  ? 10.304  -8.566  -36.456  1.00 76.65  ? 75  GLU B C     1 
ATOM   4643  O O     . GLU B 1 75  ? 10.728  -9.568  -35.897  1.00 79.09  ? 75  GLU B O     1 
ATOM   4644  C CB    . GLU B 1 75  ? 11.422  -8.329  -38.713  1.00 90.49  ? 75  GLU B CB    1 
ATOM   4645  C CG    . GLU B 1 75  ? 12.376  -9.514  -38.765  1.00 99.89  ? 75  GLU B CG    1 
ATOM   4646  C CD    . GLU B 1 75  ? 13.601  -9.274  -39.635  1.00 103.97 ? 75  GLU B CD    1 
ATOM   4647  O OE1   . GLU B 1 75  ? 14.693  -9.791  -39.304  1.00 89.82  ? 75  GLU B OE1   1 
ATOM   4648  O OE2   . GLU B 1 75  ? 13.461  -8.544  -40.638  1.00 107.69 ? 75  GLU B OE2   1 
ATOM   4649  N N     . PHE B 1 76  ? 9.962   -7.445  -35.794  1.00 79.11  ? 76  PHE B N     1 
ATOM   4650  C CA    . PHE B 1 76  ? 10.236  -7.278  -34.370  1.00 79.99  ? 76  PHE B CA    1 
ATOM   4651  C C     . PHE B 1 76  ? 8.990   -6.992  -33.530  1.00 72.24  ? 76  PHE B C     1 
ATOM   4652  O O     . PHE B 1 76  ? 9.127   -6.661  -32.354  1.00 72.39  ? 76  PHE B O     1 
ATOM   4653  C CB    . PHE B 1 76  ? 11.261  -6.157  -34.185  1.00 83.38  ? 76  PHE B CB    1 
ATOM   4654  C CG    . PHE B 1 76  ? 12.635  -6.543  -34.666  1.00 83.11  ? 76  PHE B CG    1 
ATOM   4655  C CD1   . PHE B 1 76  ? 13.394  -7.472  -33.963  1.00 82.72  ? 76  PHE B CD1   1 
ATOM   4656  C CD2   . PHE B 1 76  ? 13.142  -6.028  -35.849  1.00 79.40  ? 76  PHE B CD2   1 
ATOM   4657  C CE1   . PHE B 1 76  ? 14.649  -7.853  -34.417  1.00 83.85  ? 76  PHE B CE1   1 
ATOM   4658  C CE2   . PHE B 1 76  ? 14.391  -6.420  -36.309  1.00 91.05  ? 76  PHE B CE2   1 
ATOM   4659  C CZ    . PHE B 1 76  ? 15.140  -7.332  -35.595  1.00 88.07  ? 76  PHE B CZ    1 
ATOM   4660  N N     . GLY B 1 77  ? 7.789   -7.122  -34.110  1.00 62.72  ? 77  GLY B N     1 
ATOM   4661  C CA    . GLY B 1 77  ? 6.551   -6.867  -33.387  1.00 57.83  ? 77  GLY B CA    1 
ATOM   4662  C C     . GLY B 1 77  ? 6.443   -5.460  -32.782  1.00 67.19  ? 77  GLY B C     1 
ATOM   4663  O O     . GLY B 1 77  ? 5.755   -5.279  -31.768  1.00 60.53  ? 77  GLY B O     1 
ATOM   4664  N N     . VAL B 1 78  ? 7.052   -4.466  -33.454  1.00 62.93  ? 78  VAL B N     1 
ATOM   4665  C CA    . VAL B 1 78  ? 7.086   -3.089  -32.990  1.00 60.24  ? 78  VAL B CA    1 
ATOM   4666  C C     . VAL B 1 78  ? 5.978   -2.288  -33.653  1.00 52.49  ? 78  VAL B C     1 
ATOM   4667  O O     . VAL B 1 78  ? 6.015   -2.087  -34.848  1.00 58.19  ? 78  VAL B O     1 
ATOM   4668  C CB    . VAL B 1 78  ? 8.443   -2.436  -33.307  1.00 57.81  ? 78  VAL B CB    1 
ATOM   4669  C CG1   . VAL B 1 78  ? 8.423   -0.928  -33.112  1.00 53.57  ? 78  VAL B CG1   1 
ATOM   4670  C CG2   . VAL B 1 78  ? 9.527   -3.069  -32.468  1.00 68.70  ? 78  VAL B CG2   1 
ATOM   4671  N N     . PRO B 1 79  ? 5.033   -1.701  -32.900  1.00 63.48  ? 79  PRO B N     1 
ATOM   4672  C CA    . PRO B 1 79  ? 3.975   -0.889  -33.504  1.00 66.89  ? 79  PRO B CA    1 
ATOM   4673  C C     . PRO B 1 79  ? 4.386   0.521   -33.943  1.00 60.02  ? 79  PRO B C     1 
ATOM   4674  O O     . PRO B 1 79  ? 5.270   1.134   -33.342  1.00 61.31  ? 79  PRO B O     1 
ATOM   4675  C CB    . PRO B 1 79  ? 2.899   -0.853  -32.403  1.00 64.93  ? 79  PRO B CB    1 
ATOM   4676  C CG    . PRO B 1 79  ? 3.653   -1.037  -31.105  1.00 67.68  ? 79  PRO B CG    1 
ATOM   4677  C CD    . PRO B 1 79  ? 4.883   -1.849  -31.447  1.00 69.69  ? 79  PRO B CD    1 
ATOM   4678  N N     . LEU B 1 80  ? 3.676   1.013   -34.976  1.00 52.92  ? 80  LEU B N     1 
ATOM   4679  C CA    . LEU B 1 80  ? 3.936   2.266   -35.671  1.00 51.54  ? 80  LEU B CA    1 
ATOM   4680  C C     . LEU B 1 80  ? 2.669   3.118   -35.674  1.00 55.78  ? 80  LEU B C     1 
ATOM   4681  O O     . LEU B 1 80  ? 1.572   2.588   -35.857  1.00 53.57  ? 80  LEU B O     1 
ATOM   4682  C CB    . LEU B 1 80  ? 4.287   1.948   -37.124  1.00 52.27  ? 80  LEU B CB    1 
ATOM   4683  C CG    . LEU B 1 80  ? 5.560   1.150   -37.390  1.00 52.62  ? 80  LEU B CG    1 
ATOM   4684  C CD1   . LEU B 1 80  ? 5.687   0.840   -38.862  1.00 49.17  ? 80  LEU B CD1   1 
ATOM   4685  C CD2   . LEU B 1 80  ? 6.797   1.914   -36.933  1.00 59.88  ? 80  LEU B CD2   1 
ATOM   4686  N N     . TRP B 1 81  ? 2.836   4.438   -35.542  1.00 55.47  ? 81  TRP B N     1 
ATOM   4687  C CA    . TRP B 1 81  ? 1.723   5.370   -35.621  1.00 50.35  ? 81  TRP B CA    1 
ATOM   4688  C C     . TRP B 1 81  ? 1.947   6.318   -36.791  1.00 49.72  ? 81  TRP B C     1 
ATOM   4689  O O     . TRP B 1 81  ? 2.580   7.343   -36.607  1.00 55.78  ? 81  TRP B O     1 
ATOM   4690  C CB    . TRP B 1 81  ? 1.549   6.168   -34.321  1.00 48.39  ? 81  TRP B CB    1 
ATOM   4691  C CG    . TRP B 1 81  ? 0.274   6.955   -34.300  1.00 50.61  ? 81  TRP B CG    1 
ATOM   4692  C CD1   . TRP B 1 81  ? 0.094   8.259   -34.663  1.00 60.96  ? 81  TRP B CD1   1 
ATOM   4693  C CD2   . TRP B 1 81  ? -1.023  6.481   -33.891  1.00 51.70  ? 81  TRP B CD2   1 
ATOM   4694  N NE1   . TRP B 1 81  ? -1.222  8.628   -34.514  1.00 60.01  ? 81  TRP B NE1   1 
ATOM   4695  C CE2   . TRP B 1 81  ? -1.924  7.557   -34.035  1.00 52.17  ? 81  TRP B CE2   1 
ATOM   4696  C CE3   . TRP B 1 81  ? -1.495  5.268   -33.377  1.00 52.30  ? 81  TRP B CE3   1 
ATOM   4697  C CZ2   . TRP B 1 81  ? -3.270  7.435   -33.723  1.00 54.33  ? 81  TRP B CZ2   1 
ATOM   4698  C CZ3   . TRP B 1 81  ? -2.827  5.151   -33.065  1.00 46.25  ? 81  TRP B CZ3   1 
ATOM   4699  C CH2   . TRP B 1 81  ? -3.693  6.220   -33.237  1.00 49.07  ? 81  TRP B CH2   1 
ATOM   4700  N N     . PRO B 1 82  ? 1.402   6.064   -38.002  1.00 52.99  ? 82  PRO B N     1 
ATOM   4701  C CA    . PRO B 1 82  ? 1.660   6.918   -39.156  1.00 50.23  ? 82  PRO B CA    1 
ATOM   4702  C C     . PRO B 1 82  ? 0.968   8.263   -39.017  1.00 51.76  ? 82  PRO B C     1 
ATOM   4703  O O     . PRO B 1 82  ? -0.182  8.328   -38.601  1.00 62.07  ? 82  PRO B O     1 
ATOM   4704  C CB    . PRO B 1 82  ? 1.038   6.190   -40.347  1.00 58.49  ? 82  PRO B CB    1 
ATOM   4705  C CG    . PRO B 1 82  ? 0.715   4.804   -39.815  1.00 68.50  ? 82  PRO B CG    1 
ATOM   4706  C CD    . PRO B 1 82  ? 0.477   4.977   -38.328  1.00 61.16  ? 82  PRO B CD    1 
ATOM   4707  N N     . VAL B 1 83  ? 1.701   9.328   -39.324  1.00 53.45  ? 83  VAL B N     1 
ATOM   4708  C CA    . VAL B 1 83  ? 1.117   10.654  -39.407  1.00 58.28  ? 83  VAL B CA    1 
ATOM   4709  C C     . VAL B 1 83  ? 1.749   11.358  -40.606  1.00 59.64  ? 83  VAL B C     1 
ATOM   4710  O O     . VAL B 1 83  ? 2.921   11.137  -40.900  1.00 52.53  ? 83  VAL B O     1 
ATOM   4711  C CB    . VAL B 1 83  ? 1.300   11.455  -38.104  1.00 57.65  ? 83  VAL B CB    1 
ATOM   4712  C CG1   . VAL B 1 83  ? 1.077   10.591  -36.868  1.00 56.03  ? 83  VAL B CG1   1 
ATOM   4713  C CG2   . VAL B 1 83  ? 2.666   12.116  -38.040  1.00 65.02  ? 83  VAL B CG2   1 
ATOM   4714  N N     . SER B 1 84  ? 0.949   12.201  -41.272  1.00 64.00  ? 84  SER B N     1 
ATOM   4715  C CA    . SER B 1 84  ? 1.358   12.875  -42.490  1.00 73.19  ? 84  SER B CA    1 
ATOM   4716  C C     . SER B 1 84  ? 2.232   14.071  -42.132  1.00 73.49  ? 84  SER B C     1 
ATOM   4717  O O     . SER B 1 84  ? 3.347   14.203  -42.632  1.00 80.99  ? 84  SER B O     1 
ATOM   4718  C CB    . SER B 1 84  ? 0.166   13.283  -43.335  1.00 66.20  ? 84  SER B CB    1 
ATOM   4719  O OG    . SER B 1 84  ? -0.577  12.147  -43.753  1.00 57.33  ? 84  SER B OG    1 
ATOM   4720  N N     . ARG B 1 85  ? 1.703   14.937  -41.271  1.00 72.89  ? 85  ARG B N     1 
ATOM   4721  C CA    . ARG B 1 85  ? 2.471   16.056  -40.744  1.00 74.08  ? 85  ARG B CA    1 
ATOM   4722  C C     . ARG B 1 85  ? 2.365   16.098  -39.222  1.00 79.59  ? 85  ARG B C     1 
ATOM   4723  O O     . ARG B 1 85  ? 3.328   16.459  -38.540  1.00 76.54  ? 85  ARG B O     1 
ATOM   4724  C CB    . ARG B 1 85  ? 2.027   17.342  -41.437  1.00 66.55  ? 85  ARG B CB    1 
ATOM   4725  C CG    . ARG B 1 85  ? 2.720   17.525  -42.780  1.00 70.19  ? 85  ARG B CG    1 
ATOM   4726  C CD    . ARG B 1 85  ? 2.281   18.740  -43.567  1.00 73.60  ? 85  ARG B CD    1 
ATOM   4727  N NE    . ARG B 1 85  ? 1.936   19.896  -42.756  1.00 81.18  ? 85  ARG B NE    1 
ATOM   4728  C CZ    . ARG B 1 85  ? 2.808   20.783  -42.289  1.00 80.55  ? 85  ARG B CZ    1 
ATOM   4729  N NH1   . ARG B 1 85  ? 4.094   20.611  -42.592  1.00 58.97  ? 85  ARG B NH1   1 
ATOM   4730  N NH2   . ARG B 1 85  ? 2.362   21.815  -41.556  1.00 61.78  ? 85  ARG B NH2   1 
ATOM   4731  N N     . GLY B 1 86  ? 1.200   15.683  -38.711  1.00 81.97  ? 86  GLY B N     1 
ATOM   4732  C CA    . GLY B 1 86  ? 0.999   15.469  -37.288  1.00 82.95  ? 86  GLY B CA    1 
ATOM   4733  C C     . GLY B 1 86  ? 0.356   16.679  -36.615  1.00 80.15  ? 86  GLY B C     1 
ATOM   4734  O O     . GLY B 1 86  ? 0.410   16.787  -35.391  1.00 73.81  ? 86  GLY B O     1 
ATOM   4735  N N     . LYS B 1 87  ? -0.277  17.549  -37.425  1.00 72.86  ? 87  LYS B N     1 
ATOM   4736  C CA    . LYS B 1 87  ? -0.815  18.818  -36.958  1.00 69.91  ? 87  LYS B CA    1 
ATOM   4737  C C     . LYS B 1 87  ? -2.299  18.645  -36.622  1.00 73.77  ? 87  LYS B C     1 
ATOM   4738  O O     . LYS B 1 87  ? -3.103  19.561  -36.845  1.00 57.11  ? 87  LYS B O     1 
ATOM   4739  C CB    . LYS B 1 87  ? -0.571  19.908  -38.010  1.00 70.77  ? 87  LYS B CB    1 
ATOM   4740  C CG    . LYS B 1 87  ? 0.893   20.106  -38.400  1.00 72.29  ? 87  LYS B CG    1 
ATOM   4741  C CD    . LYS B 1 87  ? 1.715   20.935  -37.418  1.00 76.90  ? 87  LYS B CD    1 
ATOM   4742  C CE    . LYS B 1 87  ? 3.207   20.951  -37.707  1.00 71.46  ? 87  LYS B CE    1 
ATOM   4743  N NZ    . LYS B 1 87  ? 3.947   19.942  -36.905  1.00 71.66  ? 87  LYS B NZ    1 
ATOM   4744  N N     . ASN B 1 88  ? -2.619  17.465  -36.051  1.00 71.70  ? 88  ASN B N     1 
ATOM   4745  C CA    . ASN B 1 88  ? -3.974  17.075  -35.707  1.00 69.62  ? 88  ASN B CA    1 
ATOM   4746  C C     . ASN B 1 88  ? -4.279  17.616  -34.308  1.00 75.35  ? 88  ASN B C     1 
ATOM   4747  O O     . ASN B 1 88  ? -4.206  16.896  -33.316  1.00 75.33  ? 88  ASN B O     1 
ATOM   4748  C CB    . ASN B 1 88  ? -4.167  15.554  -35.817  1.00 60.63  ? 88  ASN B CB    1 
ATOM   4749  C CG    . ASN B 1 88  ? -5.595  15.143  -36.173  1.00 68.86  ? 88  ASN B CG    1 
ATOM   4750  O OD1   . ASN B 1 88  ? -6.455  15.964  -36.508  1.00 61.58  ? 88  ASN B OD1   1 
ATOM   4751  N ND2   . ASN B 1 88  ? -5.863  13.851  -36.145  1.00 67.48  ? 88  ASN B ND2   1 
ATOM   4752  N N     . PHE B 1 89  ? -4.627  18.901  -34.239  1.00 72.85  ? 89  PHE B N     1 
ATOM   4753  C CA    . PHE B 1 89  ? -4.815  19.571  -32.964  1.00 70.32  ? 89  PHE B CA    1 
ATOM   4754  C C     . PHE B 1 89  ? -6.280  19.424  -32.539  1.00 72.26  ? 89  PHE B C     1 
ATOM   4755  O O     . PHE B 1 89  ? -7.177  19.513  -33.380  1.00 68.21  ? 89  PHE B O     1 
ATOM   4756  C CB    . PHE B 1 89  ? -4.330  21.022  -33.077  1.00 72.45  ? 89  PHE B CB    1 
ATOM   4757  C CG    . PHE B 1 89  ? -2.882  21.181  -33.477  1.00 87.73  ? 89  PHE B CG    1 
ATOM   4758  C CD1   . PHE B 1 89  ? -1.864  20.619  -32.715  1.00 93.44  ? 89  PHE B CD1   1 
ATOM   4759  C CD2   . PHE B 1 89  ? -2.532  21.884  -34.630  1.00 97.64  ? 89  PHE B CD2   1 
ATOM   4760  C CE1   . PHE B 1 89  ? -0.533  20.750  -33.093  1.00 99.71  ? 89  PHE B CE1   1 
ATOM   4761  C CE2   . PHE B 1 89  ? -1.200  22.025  -35.003  1.00 98.16  ? 89  PHE B CE2   1 
ATOM   4762  C CZ    . PHE B 1 89  ? -0.201  21.462  -34.230  1.00 103.76 ? 89  PHE B CZ    1 
ATOM   4763  N N     . ALA B 1 90  ? -6.505  19.197  -31.225  1.00 70.14  ? 90  ALA B N     1 
ATOM   4764  C CA    . ALA B 1 90  ? -7.830  18.979  -30.637  1.00 74.01  ? 90  ALA B CA    1 
ATOM   4765  C C     . ALA B 1 90  ? -8.188  17.488  -30.682  1.00 73.46  ? 90  ALA B C     1 
ATOM   4766  O O     . ALA B 1 90  ? -9.183  17.052  -30.072  1.00 50.91  ? 90  ALA B O     1 
ATOM   4767  C CB    . ALA B 1 90  ? -8.890  19.827  -31.307  1.00 70.47  ? 90  ALA B CB    1 
ATOM   4768  N N     . TYR B 1 91  ? -7.292  16.739  -31.352  1.00 74.01  ? 91  TYR B N     1 
ATOM   4769  C CA    . TYR B 1 91  ? -7.440  15.329  -31.653  1.00 71.68  ? 91  TYR B CA    1 
ATOM   4770  C C     . TYR B 1 91  ? -6.189  14.556  -31.215  1.00 62.32  ? 91  TYR B C     1 
ATOM   4771  O O     . TYR B 1 91  ? -6.164  13.319  -31.247  1.00 66.71  ? 91  TYR B O     1 
ATOM   4772  C CB    . TYR B 1 91  ? -7.763  15.170  -33.145  1.00 69.14  ? 91  TYR B CB    1 
ATOM   4773  C CG    . TYR B 1 91  ? -9.061  15.804  -33.608  1.00 73.01  ? 91  TYR B CG    1 
ATOM   4774  C CD1   . TYR B 1 91  ? -10.284 15.488  -33.018  1.00 80.55  ? 91  TYR B CD1   1 
ATOM   4775  C CD2   . TYR B 1 91  ? -9.083  16.679  -34.684  1.00 64.33  ? 91  TYR B CD2   1 
ATOM   4776  C CE1   . TYR B 1 91  ? -11.478 16.045  -33.457  1.00 68.96  ? 91  TYR B CE1   1 
ATOM   4777  C CE2   . TYR B 1 91  ? -10.267 17.234  -35.143  1.00 62.53  ? 91  TYR B CE2   1 
ATOM   4778  C CZ    . TYR B 1 91  ? -11.465 16.916  -34.530  1.00 62.16  ? 91  TYR B CZ    1 
ATOM   4779  O OH    . TYR B 1 91  ? -12.610 17.499  -34.995  1.00 56.58  ? 91  TYR B OH    1 
ATOM   4780  N N     . GLY B 1 92  ? -5.156  15.277  -30.776  1.00 59.69  ? 92  GLY B N     1 
ATOM   4781  C CA    . GLY B 1 92  ? -4.013  14.652  -30.124  1.00 66.55  ? 92  GLY B CA    1 
ATOM   4782  C C     . GLY B 1 92  ? -2.642  15.004  -30.711  1.00 68.77  ? 92  GLY B C     1 
ATOM   4783  O O     . GLY B 1 92  ? -1.645  14.426  -30.279  1.00 68.39  ? 92  GLY B O     1 
ATOM   4784  N N     . GLY B 1 93  ? -2.580  15.958  -31.656  1.00 71.91  ? 93  GLY B N     1 
ATOM   4785  C CA    . GLY B 1 93  ? -1.376  16.214  -32.437  1.00 73.01  ? 93  GLY B CA    1 
ATOM   4786  C C     . GLY B 1 93  ? -0.896  14.966  -33.188  1.00 64.79  ? 93  GLY B C     1 
ATOM   4787  O O     . GLY B 1 93  ? -1.649  14.333  -33.930  1.00 74.81  ? 93  GLY B O     1 
ATOM   4788  N N     . ALA B 1 94  ? 0.361   14.597  -32.945  1.00 56.34  ? 94  ALA B N     1 
ATOM   4789  C CA    . ALA B 1 94  ? 0.965   13.429  -33.554  1.00 57.25  ? 94  ALA B CA    1 
ATOM   4790  C C     . ALA B 1 94  ? 0.962   12.225  -32.606  1.00 60.21  ? 94  ALA B C     1 
ATOM   4791  O O     . ALA B 1 94  ? 1.372   11.143  -33.007  1.00 68.49  ? 94  ALA B O     1 
ATOM   4792  C CB    . ALA B 1 94  ? 2.376   13.780  -33.972  1.00 60.96  ? 94  ALA B CB    1 
ATOM   4793  N N     . ALA B 1 95  ? 0.494   12.386  -31.358  1.00 69.50  ? 95  ALA B N     1 
ATOM   4794  C CA    . ALA B 1 95  ? 0.645   11.345  -30.343  1.00 74.08  ? 95  ALA B CA    1 
ATOM   4795  C C     . ALA B 1 95  ? -0.203  10.107  -30.686  1.00 67.95  ? 95  ALA B C     1 
ATOM   4796  O O     . ALA B 1 95  ? -1.224  10.217  -31.361  1.00 63.22  ? 95  ALA B O     1 
ATOM   4797  C CB    . ALA B 1 95  ? 0.311   11.912  -28.961  1.00 67.22  ? 95  ALA B CB    1 
ATOM   4798  N N     . PRO B 1 96  ? 0.168   8.900   -30.191  1.00 67.22  ? 96  PRO B N     1 
ATOM   4799  C CA    . PRO B 1 96  ? -0.670  7.698   -30.285  1.00 75.86  ? 96  PRO B CA    1 
ATOM   4800  C C     . PRO B 1 96  ? -1.602  7.368   -29.104  1.00 78.93  ? 96  PRO B C     1 
ATOM   4801  O O     . PRO B 1 96  ? -1.343  7.772   -27.969  1.00 72.76  ? 96  PRO B O     1 
ATOM   4802  C CB    . PRO B 1 96  ? 0.443   6.649   -30.313  1.00 70.33  ? 96  PRO B CB    1 
ATOM   4803  C CG    . PRO B 1 96  ? 1.393   7.138   -29.247  1.00 71.28  ? 96  PRO B CG    1 
ATOM   4804  C CD    . PRO B 1 96  ? 1.412   8.636   -29.456  1.00 72.26  ? 96  PRO B CD    1 
ATOM   4805  N N     . VAL B 1 97  ? -2.678  6.610   -29.384  1.00 72.86  ? 97  VAL B N     1 
ATOM   4806  C CA    . VAL B 1 97  ? -3.574  6.074   -28.365  1.00 62.69  ? 97  VAL B CA    1 
ATOM   4807  C C     . VAL B 1 97  ? -2.744  5.278   -27.360  1.00 61.95  ? 97  VAL B C     1 
ATOM   4808  O O     . VAL B 1 97  ? -2.801  5.520   -26.153  1.00 59.77  ? 97  VAL B O     1 
ATOM   4809  C CB    . VAL B 1 97  ? -4.659  5.169   -28.988  1.00 67.27  ? 97  VAL B CB    1 
ATOM   4810  C CG1   . VAL B 1 97  ? -5.480  4.452   -27.932  1.00 72.61  ? 97  VAL B CG1   1 
ATOM   4811  C CG2   . VAL B 1 97  ? -5.598  5.917   -29.922  1.00 72.45  ? 97  VAL B CG2   1 
ATOM   4812  N N     . MET B 1 98  ? -1.972  4.319   -27.885  1.00 63.82  ? 98  MET B N     1 
ATOM   4813  C CA    . MET B 1 98  ? -1.180  3.433   -27.051  1.00 72.46  ? 98  MET B CA    1 
ATOM   4814  C C     . MET B 1 98  ? 0.204   4.043   -26.805  1.00 85.57  ? 98  MET B C     1 
ATOM   4815  O O     . MET B 1 98  ? 0.778   4.696   -27.678  1.00 94.86  ? 98  MET B O     1 
ATOM   4816  C CB    . MET B 1 98  ? -1.044  2.055   -27.702  1.00 67.98  ? 98  MET B CB    1 
ATOM   4817  C CG    . MET B 1 98  ? -0.495  0.997   -26.760  1.00 68.83  ? 98  MET B CG    1 
ATOM   4818  S SD    . MET B 1 98  ? -0.443  -0.676  -27.492  1.00 82.41  ? 98  MET B SD    1 
ATOM   4819  C CE    . MET B 1 98  ? 1.034   -0.548  -28.503  1.00 75.45  ? 98  MET B CE    1 
ATOM   4820  N N     . SER B 1 99  ? 0.727   3.821   -25.592  1.00 84.84  ? 99  SER B N     1 
ATOM   4821  C CA    . SER B 1 99  ? 2.066   4.253   -25.211  1.00 85.12  ? 99  SER B CA    1 
ATOM   4822  C C     . SER B 1 99  ? 3.110   3.303   -25.784  1.00 82.83  ? 99  SER B C     1 
ATOM   4823  O O     . SER B 1 99  ? 2.861   2.103   -25.871  1.00 81.38  ? 99  SER B O     1 
ATOM   4824  C CB    . SER B 1 99  ? 2.216   4.327   -23.712  1.00 81.67  ? 99  SER B CB    1 
ATOM   4825  O OG    . SER B 1 99  ? 1.609   5.502   -23.203  1.00 85.25  ? 99  SER B OG    1 
ATOM   4826  N N     . GLY B 1 100 ? 4.284   3.854   -26.121  1.00 73.08  ? 100 GLY B N     1 
ATOM   4827  C CA    . GLY B 1 100 ? 5.409   3.061   -26.592  1.00 73.75  ? 100 GLY B CA    1 
ATOM   4828  C C     . GLY B 1 100 ? 5.430   2.914   -28.114  1.00 74.91  ? 100 GLY B C     1 
ATOM   4829  O O     . GLY B 1 100 ? 6.249   2.187   -28.674  1.00 79.45  ? 100 GLY B O     1 
ATOM   4830  N N     . THR B 1 101 ? 4.513   3.601   -28.791  1.00 70.65  ? 101 THR B N     1 
ATOM   4831  C CA    . THR B 1 101 ? 4.362   3.407   -30.215  1.00 67.11  ? 101 THR B CA    1 
ATOM   4832  C C     . THR B 1 101 ? 5.375   4.289   -30.920  1.00 67.55  ? 101 THR B C     1 
ATOM   4833  O O     . THR B 1 101 ? 5.514   5.453   -30.572  1.00 72.46  ? 101 THR B O     1 
ATOM   4834  C CB    . THR B 1 101 ? 2.938   3.737   -30.654  1.00 70.58  ? 101 THR B CB    1 
ATOM   4835  O OG1   . THR B 1 101 ? 2.016   2.977   -29.866  1.00 71.03  ? 101 THR B OG1   1 
ATOM   4836  C CG2   . THR B 1 101 ? 2.730   3.458   -32.124  1.00 79.05  ? 101 THR B CG2   1 
ATOM   4837  N N     . VAL B 1 102 ? 6.066   3.723   -31.910  1.00 68.03  ? 102 VAL B N     1 
ATOM   4838  C CA    . VAL B 1 102 ? 7.025   4.481   -32.689  1.00 65.64  ? 102 VAL B CA    1 
ATOM   4839  C C     . VAL B 1 102 ? 6.269   5.282   -33.739  1.00 59.98  ? 102 VAL B C     1 
ATOM   4840  O O     . VAL B 1 102 ? 5.594   4.693   -34.573  1.00 67.91  ? 102 VAL B O     1 
ATOM   4841  C CB    . VAL B 1 102 ? 8.064   3.566   -33.353  1.00 72.18  ? 102 VAL B CB    1 
ATOM   4842  C CG1   . VAL B 1 102 ? 8.901   4.330   -34.376  1.00 71.24  ? 102 VAL B CG1   1 
ATOM   4843  C CG2   . VAL B 1 102 ? 8.943   2.878   -32.314  1.00 67.74  ? 102 VAL B CG2   1 
ATOM   4844  N N     . VAL B 1 103 ? 6.408   6.614   -33.701  1.00 54.37  ? 103 VAL B N     1 
ATOM   4845  C CA    . VAL B 1 103 ? 5.718   7.460   -34.646  1.00 53.02  ? 103 VAL B CA    1 
ATOM   4846  C C     . VAL B 1 103 ? 6.383   7.361   -36.007  1.00 55.41  ? 103 VAL B C     1 
ATOM   4847  O O     . VAL B 1 103 ? 7.592   7.524   -36.094  1.00 50.97  ? 103 VAL B O     1 
ATOM   4848  C CB    . VAL B 1 103 ? 5.713   8.924   -34.228  1.00 51.19  ? 103 VAL B CB    1 
ATOM   4849  C CG1   . VAL B 1 103 ? 5.166   9.788   -35.360  1.00 56.12  ? 103 VAL B CG1   1 
ATOM   4850  C CG2   . VAL B 1 103 ? 4.913   9.114   -32.969  1.00 54.87  ? 103 VAL B CG2   1 
ATOM   4851  N N     . LEU B 1 104 ? 5.559   7.172   -37.048  1.00 57.79  ? 104 LEU B N     1 
ATOM   4852  C CA    . LEU B 1 104 ? 6.022   7.149   -38.430  1.00 58.36  ? 104 LEU B CA    1 
ATOM   4853  C C     . LEU B 1 104 ? 5.596   8.461   -39.077  1.00 54.84  ? 104 LEU B C     1 
ATOM   4854  O O     . LEU B 1 104 ? 4.503   8.581   -39.630  1.00 58.76  ? 104 LEU B O     1 
ATOM   4855  C CB    . LEU B 1 104 ? 5.490   5.903   -39.158  1.00 55.82  ? 104 LEU B CB    1 
ATOM   4856  C CG    . LEU B 1 104 ? 5.695   5.858   -40.672  1.00 61.99  ? 104 LEU B CG    1 
ATOM   4857  C CD1   . LEU B 1 104 ? 7.172   5.910   -41.026  1.00 70.10  ? 104 LEU B CD1   1 
ATOM   4858  C CD2   . LEU B 1 104 ? 5.032   4.621   -41.273  1.00 57.06  ? 104 LEU B CD2   1 
ATOM   4859  N N     . ASP B 1 105 ? 6.488   9.445   -38.959  1.00 50.84  ? 105 ASP B N     1 
ATOM   4860  C CA    . ASP B 1 105 ? 6.271   10.795  -39.442  1.00 53.98  ? 105 ASP B CA    1 
ATOM   4861  C C     . ASP B 1 105 ? 6.627   10.907  -40.920  1.00 52.86  ? 105 ASP B C     1 
ATOM   4862  O O     . ASP B 1 105 ? 7.671   10.401  -41.338  1.00 58.68  ? 105 ASP B O     1 
ATOM   4863  C CB    . ASP B 1 105 ? 7.163   11.714  -38.622  1.00 56.39  ? 105 ASP B CB    1 
ATOM   4864  C CG    . ASP B 1 105 ? 6.955   13.194  -38.812  1.00 60.39  ? 105 ASP B CG    1 
ATOM   4865  O OD1   . ASP B 1 105 ? 6.021   13.602  -39.547  1.00 65.25  ? 105 ASP B OD1   1 
ATOM   4866  O OD2   . ASP B 1 105 ? 7.742   13.914  -38.203  1.00 70.65  ? 105 ASP B OD2   1 
ATOM   4867  N N     . MET B 1 106 ? 5.807   11.631  -41.697  1.00 55.15  ? 106 MET B N     1 
ATOM   4868  C CA    . MET B 1 106 ? 6.020   11.682  -43.140  1.00 55.82  ? 106 MET B CA    1 
ATOM   4869  C C     . MET B 1 106 ? 6.094   13.122  -43.650  1.00 55.13  ? 106 MET B C     1 
ATOM   4870  O O     . MET B 1 106 ? 5.907   13.377  -44.839  1.00 58.92  ? 106 MET B O     1 
ATOM   4871  C CB    . MET B 1 106 ? 4.940   10.863  -43.846  1.00 56.60  ? 106 MET B CB    1 
ATOM   4872  C CG    . MET B 1 106 ? 5.006   9.428   -43.367  1.00 65.09  ? 106 MET B CG    1 
ATOM   4873  S SD    . MET B 1 106 ? 4.272   8.184   -44.418  1.00 73.38  ? 106 MET B SD    1 
ATOM   4874  C CE    . MET B 1 106 ? 2.603   8.817   -44.527  1.00 89.74  ? 106 MET B CE    1 
ATOM   4875  N N     . ASN B 1 107 ? 6.508   14.027  -42.757  1.00 58.13  ? 107 ASN B N     1 
ATOM   4876  C CA    . ASN B 1 107 ? 6.860   15.397  -43.095  1.00 61.21  ? 107 ASN B CA    1 
ATOM   4877  C C     . ASN B 1 107 ? 7.687   15.455  -44.365  1.00 50.57  ? 107 ASN B C     1 
ATOM   4878  O O     . ASN B 1 107 ? 7.500   16.360  -45.143  1.00 47.90  ? 107 ASN B O     1 
ATOM   4879  C CB    . ASN B 1 107 ? 7.690   16.092  -42.002  1.00 66.89  ? 107 ASN B CB    1 
ATOM   4880  C CG    . ASN B 1 107 ? 6.856   17.032  -41.163  1.00 88.44  ? 107 ASN B CG    1 
ATOM   4881  O OD1   . ASN B 1 107 ? 6.423   16.676  -40.069  1.00 112.39 ? 107 ASN B OD1   1 
ATOM   4882  N ND2   . ASN B 1 107 ? 6.567   18.209  -41.696  1.00 90.41  ? 107 ASN B ND2   1 
ATOM   4883  N N     . ARG B 1 108 ? 8.660   14.551  -44.501  1.00 58.61  ? 108 ARG B N     1 
ATOM   4884  C CA    . ARG B 1 108 ? 9.735   14.723  -45.467  1.00 64.18  ? 108 ARG B CA    1 
ATOM   4885  C C     . ARG B 1 108 ? 9.254   14.349  -46.864  1.00 63.71  ? 108 ARG B C     1 
ATOM   4886  O O     . ARG B 1 108 ? 9.712   14.917  -47.845  1.00 56.55  ? 108 ARG B O     1 
ATOM   4887  C CB    . ARG B 1 108 ? 10.951  13.876  -45.075  1.00 67.63  ? 108 ARG B CB    1 
ATOM   4888  C CG    . ARG B 1 108 ? 11.634  14.346  -43.799  1.00 68.36  ? 108 ARG B CG    1 
ATOM   4889  C CD    . ARG B 1 108 ? 12.773  13.435  -43.385  1.00 68.62  ? 108 ARG B CD    1 
ATOM   4890  N NE    . ARG B 1 108 ? 13.884  13.495  -44.320  1.00 67.47  ? 108 ARG B NE    1 
ATOM   4891  C CZ    . ARG B 1 108 ? 14.569  12.448  -44.758  1.00 65.43  ? 108 ARG B CZ    1 
ATOM   4892  N NH1   . ARG B 1 108 ? 14.352  11.247  -44.264  1.00 63.76  ? 108 ARG B NH1   1 
ATOM   4893  N NH2   . ARG B 1 108 ? 15.505  12.607  -45.676  1.00 70.15  ? 108 ARG B NH2   1 
ATOM   4894  N N     . MET B 1 109 ? 8.345   13.374  -46.935  1.00 62.72  ? 109 MET B N     1 
ATOM   4895  C CA    . MET B 1 109 ? 7.634   13.071  -48.162  1.00 54.85  ? 109 MET B CA    1 
ATOM   4896  C C     . MET B 1 109 ? 6.636   14.192  -48.464  1.00 52.95  ? 109 MET B C     1 
ATOM   4897  O O     . MET B 1 109 ? 5.443   14.056  -48.224  1.00 62.06  ? 109 MET B O     1 
ATOM   4898  C CB    . MET B 1 109 ? 6.912   11.729  -47.997  1.00 54.79  ? 109 MET B CB    1 
ATOM   4899  C CG    . MET B 1 109 ? 7.846   10.541  -48.018  1.00 52.68  ? 109 MET B CG    1 
ATOM   4900  S SD    . MET B 1 109 ? 7.120   9.014   -47.374  1.00 61.35  ? 109 MET B SD    1 
ATOM   4901  C CE    . MET B 1 109 ? 6.309   8.375   -48.841  1.00 62.76  ? 109 MET B CE    1 
ATOM   4902  N N     . ASN B 1 110 ? 7.126   15.295  -49.036  1.00 54.75  ? 110 ASN B N     1 
ATOM   4903  C CA    . ASN B 1 110 ? 6.322   16.492  -49.269  1.00 51.25  ? 110 ASN B CA    1 
ATOM   4904  C C     . ASN B 1 110 ? 6.364   16.952  -50.739  1.00 46.34  ? 110 ASN B C     1 
ATOM   4905  O O     . ASN B 1 110 ? 6.125   18.133  -51.003  1.00 44.21  ? 110 ASN B O     1 
ATOM   4906  C CB    . ASN B 1 110 ? 6.777   17.612  -48.328  1.00 55.59  ? 110 ASN B CB    1 
ATOM   4907  C CG    . ASN B 1 110 ? 8.206   18.044  -48.599  1.00 56.52  ? 110 ASN B CG    1 
ATOM   4908  O OD1   . ASN B 1 110 ? 9.020   17.219  -48.999  1.00 50.68  ? 110 ASN B OD1   1 
ATOM   4909  N ND2   . ASN B 1 110 ? 8.491   19.334  -48.495  1.00 54.31  ? 110 ASN B ND2   1 
ATOM   4910  N N     . ARG B 1 111 ? 6.624   16.025  -51.687  1.00 49.72  ? 111 ARG B N     1 
ATOM   4911  C CA    . ARG B 1 111 ? 6.516   16.281  -53.124  1.00 59.78  ? 111 ARG B CA    1 
ATOM   4912  C C     . ARG B 1 111 ? 5.076   16.595  -53.548  1.00 63.46  ? 111 ARG B C     1 
ATOM   4913  O O     . ARG B 1 111 ? 4.167   15.771  -53.366  1.00 62.39  ? 111 ARG B O     1 
ATOM   4914  C CB    . ARG B 1 111 ? 6.969   15.065  -53.945  1.00 63.95  ? 111 ARG B CB    1 
ATOM   4915  C CG    . ARG B 1 111 ? 8.366   15.161  -54.546  1.00 78.78  ? 111 ARG B CG    1 
ATOM   4916  C CD    . ARG B 1 111 ? 9.116   13.839  -54.427  1.00 93.98  ? 111 ARG B CD    1 
ATOM   4917  N NE    . ARG B 1 111 ? 9.306   13.473  -53.018  1.00 97.35  ? 111 ARG B NE    1 
ATOM   4918  C CZ    . ARG B 1 111 ? 10.041  12.460  -52.563  1.00 90.17  ? 111 ARG B CZ    1 
ATOM   4919  N NH1   . ARG B 1 111 ? 10.804  11.751  -53.379  1.00 82.63  ? 111 ARG B NH1   1 
ATOM   4920  N NH2   . ARG B 1 111 ? 10.023  12.183  -51.270  1.00 83.48  ? 111 ARG B NH2   1 
ATOM   4921  N N     . ILE B 1 112 ? 4.872   17.767  -54.165  1.00 54.19  ? 112 ILE B N     1 
ATOM   4922  C CA    . ILE B 1 112 ? 3.690   17.957  -54.989  1.00 51.92  ? 112 ILE B CA    1 
ATOM   4923  C C     . ILE B 1 112 ? 3.923   17.258  -56.324  1.00 54.20  ? 112 ILE B C     1 
ATOM   4924  O O     . ILE B 1 112 ? 4.627   17.778  -57.168  1.00 55.08  ? 112 ILE B O     1 
ATOM   4925  C CB    . ILE B 1 112 ? 3.388   19.444  -55.212  1.00 53.34  ? 112 ILE B CB    1 
ATOM   4926  C CG1   . ILE B 1 112 ? 3.046   20.159  -53.900  1.00 56.42  ? 112 ILE B CG1   1 
ATOM   4927  C CG2   . ILE B 1 112 ? 2.284   19.589  -56.257  1.00 54.64  ? 112 ILE B CG2   1 
ATOM   4928  C CD1   . ILE B 1 112 ? 2.957   21.665  -54.040  1.00 54.12  ? 112 ILE B CD1   1 
ATOM   4929  N N     . LEU B 1 113 ? 3.334   16.085  -56.528  1.00 51.93  ? 113 LEU B N     1 
ATOM   4930  C CA    . LEU B 1 113 ? 3.668   15.291  -57.696  1.00 50.05  ? 113 LEU B CA    1 
ATOM   4931  C C     . LEU B 1 113 ? 3.050   15.849  -58.985  1.00 51.18  ? 113 LEU B C     1 
ATOM   4932  O O     . LEU B 1 113 ? 3.576   15.630  -60.073  1.00 42.48  ? 113 LEU B O     1 
ATOM   4933  C CB    . LEU B 1 113 ? 3.208   13.859  -57.422  1.00 48.57  ? 113 LEU B CB    1 
ATOM   4934  C CG    . LEU B 1 113 ? 3.952   13.130  -56.303  1.00 47.94  ? 113 LEU B CG    1 
ATOM   4935  C CD1   . LEU B 1 113 ? 3.286   11.803  -55.990  1.00 50.82  ? 113 LEU B CD1   1 
ATOM   4936  C CD2   . LEU B 1 113 ? 5.414   12.883  -56.642  1.00 46.01  ? 113 LEU B CD2   1 
ATOM   4937  N N     . GLU B 1 114 ? 1.924   16.563  -58.874  1.00 56.89  ? 114 GLU B N     1 
ATOM   4938  C CA    . GLU B 1 114 ? 1.272   17.144  -60.035  1.00 50.96  ? 114 GLU B CA    1 
ATOM   4939  C C     . GLU B 1 114 ? 0.105   18.040  -59.622  1.00 51.86  ? 114 GLU B C     1 
ATOM   4940  O O     . GLU B 1 114 ? -0.731  17.679  -58.806  1.00 46.16  ? 114 GLU B O     1 
ATOM   4941  C CB    . GLU B 1 114 ? 0.760   16.063  -60.980  1.00 51.64  ? 114 GLU B CB    1 
ATOM   4942  C CG    . GLU B 1 114 ? -0.392  16.546  -61.833  1.00 62.06  ? 114 GLU B CG    1 
ATOM   4943  C CD    . GLU B 1 114 ? -0.502  15.930  -63.215  1.00 71.79  ? 114 GLU B CD    1 
ATOM   4944  O OE1   . GLU B 1 114 ? -0.430  14.670  -63.299  1.00 69.50  ? 114 GLU B OE1   1 
ATOM   4945  O OE2   . GLU B 1 114 ? -0.685  16.724  -64.197  1.00 66.19  ? 114 GLU B OE2   1 
ATOM   4946  N N     . VAL B 1 115 ? 0.053   19.228  -60.224  1.00 50.75  ? 115 VAL B N     1 
ATOM   4947  C CA    . VAL B 1 115 ? -1.152  20.014  -60.249  1.00 45.83  ? 115 VAL B CA    1 
ATOM   4948  C C     . VAL B 1 115 ? -1.512  20.270  -61.709  1.00 54.65  ? 115 VAL B C     1 
ATOM   4949  O O     . VAL B 1 115 ? -0.738  20.872  -62.436  1.00 55.00  ? 115 VAL B O     1 
ATOM   4950  C CB    . VAL B 1 115 ? -1.009  21.324  -59.475  1.00 47.58  ? 115 VAL B CB    1 
ATOM   4951  C CG1   . VAL B 1 115 ? -2.288  22.141  -59.562  1.00 48.67  ? 115 VAL B CG1   1 
ATOM   4952  C CG2   . VAL B 1 115 ? -0.652  21.049  -58.024  1.00 53.60  ? 115 VAL B CG2   1 
ATOM   4953  N N     . ASN B 1 116 ? -2.738  19.853  -62.060  1.00 56.95  ? 116 ASN B N     1 
ATOM   4954  C CA    . ASN B 1 116 ? -3.306  19.908  -63.383  1.00 47.81  ? 116 ASN B CA    1 
ATOM   4955  C C     . ASN B 1 116 ? -4.500  20.855  -63.430  1.00 46.31  ? 116 ASN B C     1 
ATOM   4956  O O     . ASN B 1 116 ? -5.550  20.553  -62.892  1.00 43.63  ? 116 ASN B O     1 
ATOM   4957  C CB    . ASN B 1 116 ? -3.752  18.511  -63.752  1.00 49.88  ? 116 ASN B CB    1 
ATOM   4958  C CG    . ASN B 1 116 ? -4.223  18.450  -65.177  1.00 48.20  ? 116 ASN B CG    1 
ATOM   4959  O OD1   . ASN B 1 116 ? -4.989  19.301  -65.617  1.00 49.24  ? 116 ASN B OD1   1 
ATOM   4960  N ND2   . ASN B 1 116 ? -3.756  17.450  -65.894  1.00 53.79  ? 116 ASN B ND2   1 
ATOM   4961  N N     . GLU B 1 117 ? -4.364  21.967  -64.152  1.00 52.85  ? 117 GLU B N     1 
ATOM   4962  C CA    . GLU B 1 117 ? -5.354  23.036  -64.173  1.00 51.43  ? 117 GLU B CA    1 
ATOM   4963  C C     . GLU B 1 117 ? -6.590  22.656  -64.988  1.00 52.27  ? 117 GLU B C     1 
ATOM   4964  O O     . GLU B 1 117 ? -7.707  23.038  -64.621  1.00 46.52  ? 117 GLU B O     1 
ATOM   4965  C CB    . GLU B 1 117 ? -4.681  24.283  -64.744  1.00 51.01  ? 117 GLU B CB    1 
ATOM   4966  C CG    . GLU B 1 117 ? -5.569  25.507  -64.917  1.00 54.19  ? 117 GLU B CG    1 
ATOM   4967  C CD    . GLU B 1 117 ? -4.777  26.680  -65.483  1.00 62.64  ? 117 GLU B CD    1 
ATOM   4968  O OE1   . GLU B 1 117 ? -4.166  26.496  -66.556  1.00 66.74  ? 117 GLU B OE1   1 
ATOM   4969  O OE2   . GLU B 1 117 ? -4.692  27.743  -64.822  1.00 65.48  ? 117 GLU B OE2   1 
ATOM   4970  N N     . GLU B 1 118 ? -6.380  21.939  -66.105  1.00 51.99  ? 118 GLU B N     1 
ATOM   4971  C CA    . GLU B 1 118 ? -7.441  21.747  -67.082  1.00 58.29  ? 118 GLU B CA    1 
ATOM   4972  C C     . GLU B 1 118 ? -8.442  20.695  -66.596  1.00 60.78  ? 118 GLU B C     1 
ATOM   4973  O O     . GLU B 1 118 ? -9.626  20.764  -66.939  1.00 56.81  ? 118 GLU B O     1 
ATOM   4974  C CB    . GLU B 1 118 ? -6.897  21.405  -68.479  1.00 67.21  ? 118 GLU B CB    1 
ATOM   4975  C CG    . GLU B 1 118 ? -5.878  20.271  -68.547  1.00 74.40  ? 118 GLU B CG    1 
ATOM   4976  C CD    . GLU B 1 118 ? -5.656  19.614  -69.911  1.00 76.85  ? 118 GLU B CD    1 
ATOM   4977  O OE1   . GLU B 1 118 ? -6.429  19.879  -70.862  1.00 68.04  ? 118 GLU B OE1   1 
ATOM   4978  O OE2   . GLU B 1 118 ? -4.705  18.811  -70.024  1.00 74.65  ? 118 GLU B OE2   1 
ATOM   4979  N N     . PHE B 1 119 ? -7.945  19.706  -65.839  1.00 58.78  ? 119 PHE B N     1 
ATOM   4980  C CA    . PHE B 1 119 ? -8.780  18.689  -65.216  1.00 59.20  ? 119 PHE B CA    1 
ATOM   4981  C C     . PHE B 1 119 ? -9.056  19.013  -63.739  1.00 53.31  ? 119 PHE B C     1 
ATOM   4982  O O     . PHE B 1 119 ? -9.775  18.266  -63.080  1.00 45.62  ? 119 PHE B O     1 
ATOM   4983  C CB    . PHE B 1 119 ? -8.118  17.308  -65.280  1.00 60.91  ? 119 PHE B CB    1 
ATOM   4984  C CG    . PHE B 1 119 ? -7.781  16.784  -66.651  1.00 61.36  ? 119 PHE B CG    1 
ATOM   4985  C CD1   . PHE B 1 119 ? -8.679  16.897  -67.697  1.00 62.20  ? 119 PHE B CD1   1 
ATOM   4986  C CD2   . PHE B 1 119 ? -6.577  16.131  -66.876  1.00 65.28  ? 119 PHE B CD2   1 
ATOM   4987  C CE1   . PHE B 1 119 ? -8.354  16.414  -68.949  1.00 58.55  ? 119 PHE B CE1   1 
ATOM   4988  C CE2   . PHE B 1 119 ? -6.252  15.642  -68.130  1.00 60.96  ? 119 PHE B CE2   1 
ATOM   4989  C CZ    . PHE B 1 119 ? -7.146  15.789  -69.161  1.00 60.37  ? 119 PHE B CZ    1 
ATOM   4990  N N     . GLY B 1 120 ? -8.485  20.108  -63.221  1.00 46.82  ? 120 GLY B N     1 
ATOM   4991  C CA    . GLY B 1 120 ? -8.745  20.549  -61.857  1.00 48.12  ? 120 GLY B CA    1 
ATOM   4992  C C     . GLY B 1 120 ? -8.357  19.502  -60.812  1.00 46.36  ? 120 GLY B C     1 
ATOM   4993  O O     . GLY B 1 120 ? -9.228  19.003  -60.121  1.00 45.32  ? 120 GLY B O     1 
ATOM   4994  N N     . TYR B 1 121 ? -7.069  19.158  -60.683  1.00 43.54  ? 121 TYR B N     1 
ATOM   4995  C CA    . TYR B 1 121 ? -6.700  18.196  -59.664  1.00 48.36  ? 121 TYR B CA    1 
ATOM   4996  C C     . TYR B 1 121 ? -5.258  18.363  -59.213  1.00 49.37  ? 121 TYR B C     1 
ATOM   4997  O O     . TYR B 1 121 ? -4.494  18.994  -59.911  1.00 54.82  ? 121 TYR B O     1 
ATOM   4998  C CB    . TYR B 1 121 ? -6.969  16.779  -60.160  1.00 45.06  ? 121 TYR B CB    1 
ATOM   4999  C CG    . TYR B 1 121 ? -5.952  16.138  -61.068  1.00 43.61  ? 121 TYR B CG    1 
ATOM   5000  C CD1   . TYR B 1 121 ? -4.740  15.687  -60.588  1.00 40.98  ? 121 TYR B CD1   1 
ATOM   5001  C CD2   . TYR B 1 121 ? -6.261  15.868  -62.394  1.00 42.49  ? 121 TYR B CD2   1 
ATOM   5002  C CE1   . TYR B 1 121 ? -3.858  14.993  -61.404  1.00 46.47  ? 121 TYR B CE1   1 
ATOM   5003  C CE2   . TYR B 1 121 ? -5.376  15.228  -63.235  1.00 39.95  ? 121 TYR B CE2   1 
ATOM   5004  C CZ    . TYR B 1 121 ? -4.173  14.761  -62.736  1.00 47.51  ? 121 TYR B CZ    1 
ATOM   5005  O OH    . TYR B 1 121 ? -3.285  14.094  -63.559  1.00 39.88  ? 121 TYR B OH    1 
ATOM   5006  N N     . ALA B 1 122 ? -4.919  17.797  -58.038  1.00 50.72  ? 122 ALA B N     1 
ATOM   5007  C CA    . ALA B 1 122 ? -3.531  17.595  -57.646  1.00 47.31  ? 122 ALA B CA    1 
ATOM   5008  C C     . ALA B 1 122 ? -3.286  16.145  -57.244  1.00 50.59  ? 122 ALA B C     1 
ATOM   5009  O O     . ALA B 1 122 ? -4.218  15.423  -56.897  1.00 50.54  ? 122 ALA B O     1 
ATOM   5010  C CB    . ALA B 1 122 ? -3.156  18.506  -56.521  1.00 51.33  ? 122 ALA B CB    1 
ATOM   5011  N N     . LEU B 1 123 ? -2.014  15.734  -57.347  1.00 48.76  ? 123 LEU B N     1 
ATOM   5012  C CA    . LEU B 1 123 ? -1.518  14.521  -56.732  1.00 49.80  ? 123 LEU B CA    1 
ATOM   5013  C C     . LEU B 1 123 ? -0.409  14.907  -55.752  1.00 54.68  ? 123 LEU B C     1 
ATOM   5014  O O     . LEU B 1 123 ? 0.582   15.510  -56.148  1.00 62.07  ? 123 LEU B O     1 
ATOM   5015  C CB    . LEU B 1 123 ? -1.017  13.572  -57.826  1.00 49.87  ? 123 LEU B CB    1 
ATOM   5016  C CG    . LEU B 1 123 ? -0.401  12.262  -57.313  1.00 50.00  ? 123 LEU B CG    1 
ATOM   5017  C CD1   . LEU B 1 123 ? -1.443  11.377  -56.629  1.00 47.12  ? 123 LEU B CD1   1 
ATOM   5018  C CD2   . LEU B 1 123 ? 0.298   11.494  -58.426  1.00 46.52  ? 123 LEU B CD2   1 
ATOM   5019  N N     . VAL B 1 124 ? -0.578  14.551  -54.471  1.00 60.32  ? 124 VAL B N     1 
ATOM   5020  C CA    . VAL B 1 124 ? 0.277   15.048  -53.399  1.00 54.89  ? 124 VAL B CA    1 
ATOM   5021  C C     . VAL B 1 124 ? 0.724   13.891  -52.511  1.00 53.93  ? 124 VAL B C     1 
ATOM   5022  O O     . VAL B 1 124 ? -0.005  12.906  -52.346  1.00 50.00  ? 124 VAL B O     1 
ATOM   5023  C CB    . VAL B 1 124 ? -0.469  16.089  -52.561  1.00 58.33  ? 124 VAL B CB    1 
ATOM   5024  C CG1   . VAL B 1 124 ? -0.691  17.383  -53.337  1.00 61.19  ? 124 VAL B CG1   1 
ATOM   5025  C CG2   . VAL B 1 124 ? -1.789  15.509  -52.053  1.00 58.28  ? 124 VAL B CG2   1 
ATOM   5026  N N     . GLU B 1 125 ? 1.936   14.043  -51.960  1.00 50.30  ? 125 GLU B N     1 
ATOM   5027  C CA    . GLU B 1 125 ? 2.439   13.192  -50.894  1.00 49.68  ? 125 GLU B CA    1 
ATOM   5028  C C     . GLU B 1 125 ? 1.928   13.698  -49.536  1.00 44.18  ? 125 GLU B C     1 
ATOM   5029  O O     . GLU B 1 125 ? 1.420   14.823  -49.403  1.00 35.66  ? 125 GLU B O     1 
ATOM   5030  C CB    . GLU B 1 125 ? 3.973   13.195  -50.911  1.00 56.86  ? 125 GLU B CB    1 
ATOM   5031  C CG    . GLU B 1 125 ? 4.611   12.550  -52.141  1.00 59.78  ? 125 GLU B CG    1 
ATOM   5032  C CD    . GLU B 1 125 ? 6.100   12.245  -51.988  1.00 63.05  ? 125 GLU B CD    1 
ATOM   5033  O OE1   . GLU B 1 125 ? 6.816   13.077  -51.362  1.00 53.20  ? 125 GLU B OE1   1 
ATOM   5034  O OE2   . GLU B 1 125 ? 6.557   11.192  -52.506  1.00 58.61  ? 125 GLU B OE2   1 
ATOM   5035  N N     . PRO B 1 126 ? 2.040   12.890  -48.455  1.00 41.85  ? 126 PRO B N     1 
ATOM   5036  C CA    . PRO B 1 126 ? 1.494   13.285  -47.156  1.00 42.93  ? 126 PRO B CA    1 
ATOM   5037  C C     . PRO B 1 126 ? 2.036   14.559  -46.512  1.00 45.17  ? 126 PRO B C     1 
ATOM   5038  O O     . PRO B 1 126 ? 1.299   15.232  -45.807  1.00 50.25  ? 126 PRO B O     1 
ATOM   5039  C CB    . PRO B 1 126 ? 1.806   12.068  -46.302  1.00 44.33  ? 126 PRO B CB    1 
ATOM   5040  C CG    . PRO B 1 126 ? 1.800   10.931  -47.304  1.00 44.63  ? 126 PRO B CG    1 
ATOM   5041  C CD    . PRO B 1 126 ? 2.591   11.530  -48.437  1.00 43.34  ? 126 PRO B CD    1 
ATOM   5042  N N     . GLY B 1 127 ? 3.280   14.936  -46.825  1.00 46.10  ? 127 GLY B N     1 
ATOM   5043  C CA    . GLY B 1 127 ? 3.936   16.084  -46.219  1.00 41.42  ? 127 GLY B CA    1 
ATOM   5044  C C     . GLY B 1 127 ? 3.500   17.430  -46.792  1.00 44.37  ? 127 GLY B C     1 
ATOM   5045  O O     . GLY B 1 127 ? 3.890   18.487  -46.290  1.00 47.86  ? 127 GLY B O     1 
ATOM   5046  N N     . VAL B 1 128 ? 2.695   17.420  -47.850  1.00 50.32  ? 128 VAL B N     1 
ATOM   5047  C CA    . VAL B 1 128 ? 2.333   18.677  -48.483  1.00 51.97  ? 128 VAL B CA    1 
ATOM   5048  C C     . VAL B 1 128 ? 1.375   19.392  -47.543  1.00 48.91  ? 128 VAL B C     1 
ATOM   5049  O O     . VAL B 1 128 ? 0.281   18.902  -47.280  1.00 60.25  ? 128 VAL B O     1 
ATOM   5050  C CB    . VAL B 1 128 ? 1.728   18.494  -49.892  1.00 47.51  ? 128 VAL B CB    1 
ATOM   5051  C CG1   . VAL B 1 128 ? 1.240   19.813  -50.490  1.00 44.94  ? 128 VAL B CG1   1 
ATOM   5052  C CG2   . VAL B 1 128 ? 2.712   17.826  -50.832  1.00 49.88  ? 128 VAL B CG2   1 
ATOM   5053  N N     . SER B 1 129 ? 1.792   20.537  -47.028  1.00 47.76  ? 129 SER B N     1 
ATOM   5054  C CA    . SER B 1 129 ? 0.854   21.334  -46.262  1.00 55.41  ? 129 SER B CA    1 
ATOM   5055  C C     . SER B 1 129 ? -0.090  22.012  -47.229  1.00 49.35  ? 129 SER B C     1 
ATOM   5056  O O     . SER B 1 129 ? 0.237   22.148  -48.403  1.00 52.51  ? 129 SER B O     1 
ATOM   5057  C CB    . SER B 1 129 ? 1.536   22.371  -45.429  1.00 59.30  ? 129 SER B CB    1 
ATOM   5058  O OG    . SER B 1 129 ? 2.203   23.309  -46.264  1.00 64.41  ? 129 SER B OG    1 
ATOM   5059  N N     . TYR B 1 130 ? -1.197  22.511  -46.685  1.00 46.36  ? 130 TYR B N     1 
ATOM   5060  C CA    . TYR B 1 130 ? -2.056  23.436  -47.404  1.00 47.32  ? 130 TYR B CA    1 
ATOM   5061  C C     . TYR B 1 130 ? -1.288  24.695  -47.808  1.00 45.80  ? 130 TYR B C     1 
ATOM   5062  O O     . TYR B 1 130 ? -1.485  25.196  -48.914  1.00 49.19  ? 130 TYR B O     1 
ATOM   5063  C CB    . TYR B 1 130 ? -3.284  23.814  -46.571  1.00 46.35  ? 130 TYR B CB    1 
ATOM   5064  C CG    . TYR B 1 130 ? -4.230  22.684  -46.256  1.00 48.39  ? 130 TYR B CG    1 
ATOM   5065  C CD1   . TYR B 1 130 ? -5.113  22.211  -47.223  1.00 49.67  ? 130 TYR B CD1   1 
ATOM   5066  C CD2   . TYR B 1 130 ? -4.264  22.099  -44.990  1.00 48.43  ? 130 TYR B CD2   1 
ATOM   5067  C CE1   . TYR B 1 130 ? -6.017  21.201  -46.952  1.00 47.02  ? 130 TYR B CE1   1 
ATOM   5068  C CE2   . TYR B 1 130 ? -5.130  21.047  -44.717  1.00 47.12  ? 130 TYR B CE2   1 
ATOM   5069  C CZ    . TYR B 1 130 ? -6.011  20.607  -45.698  1.00 49.71  ? 130 TYR B CZ    1 
ATOM   5070  O OH    . TYR B 1 130 ? -6.894  19.583  -45.460  1.00 48.51  ? 130 TYR B OH    1 
ATOM   5071  N N     . PHE B 1 131 ? -0.435  25.226  -46.917  1.00 50.75  ? 131 PHE B N     1 
ATOM   5072  C CA    . PHE B 1 131 ? 0.405   26.379  -47.259  1.00 50.59  ? 131 PHE B CA    1 
ATOM   5073  C C     . PHE B 1 131 ? 1.258   26.116  -48.506  1.00 41.66  ? 131 PHE B C     1 
ATOM   5074  O O     . PHE B 1 131 ? 1.240   26.912  -49.436  1.00 38.42  ? 131 PHE B O     1 
ATOM   5075  C CB    . PHE B 1 131 ? 1.279   26.818  -46.083  1.00 47.08  ? 131 PHE B CB    1 
ATOM   5076  C CG    . PHE B 1 131 ? 0.553   27.685  -45.092  1.00 49.85  ? 131 PHE B CG    1 
ATOM   5077  C CD1   . PHE B 1 131 ? 0.082   28.930  -45.463  1.00 60.99  ? 131 PHE B CD1   1 
ATOM   5078  C CD2   . PHE B 1 131 ? 0.304   27.250  -43.807  1.00 53.67  ? 131 PHE B CD2   1 
ATOM   5079  C CE1   . PHE B 1 131 ? -0.598  29.732  -44.556  1.00 59.81  ? 131 PHE B CE1   1 
ATOM   5080  C CE2   . PHE B 1 131 ? -0.393  28.042  -42.907  1.00 55.70  ? 131 PHE B CE2   1 
ATOM   5081  C CZ    . PHE B 1 131 ? -0.849  29.277  -43.288  1.00 57.75  ? 131 PHE B CZ    1 
ATOM   5082  N N     . GLU B 1 132 ? 1.949   24.978  -48.548  1.00 39.81  ? 132 GLU B N     1 
ATOM   5083  C CA    . GLU B 1 132 ? 2.780   24.636  -49.687  1.00 49.70  ? 132 GLU B CA    1 
ATOM   5084  C C     . GLU B 1 132 ? 1.939   24.603  -50.959  1.00 51.89  ? 132 GLU B C     1 
ATOM   5085  O O     . GLU B 1 132 ? 2.347   25.187  -51.953  1.00 58.92  ? 132 GLU B O     1 
ATOM   5086  C CB    . GLU B 1 132 ? 3.506   23.298  -49.522  1.00 61.61  ? 132 GLU B CB    1 
ATOM   5087  C CG    . GLU B 1 132 ? 4.603   23.283  -48.461  1.00 68.00  ? 132 GLU B CG    1 
ATOM   5088  C CD    . GLU B 1 132 ? 5.287   21.930  -48.298  1.00 78.59  ? 132 GLU B CD    1 
ATOM   5089  O OE1   . GLU B 1 132 ? 5.202   21.056  -49.241  1.00 70.10  ? 132 GLU B OE1   1 
ATOM   5090  O OE2   . GLU B 1 132 ? 5.911   21.743  -47.230  1.00 82.24  ? 132 GLU B OE2   1 
ATOM   5091  N N     . LEU B 1 133 ? 0.762   23.961  -50.922  1.00 58.35  ? 133 LEU B N     1 
ATOM   5092  C CA    . LEU B 1 133 ? -0.013  23.745  -52.136  1.00 53.17  ? 133 LEU B CA    1 
ATOM   5093  C C     . LEU B 1 133 ? -0.635  25.054  -52.619  1.00 52.88  ? 133 LEU B C     1 
ATOM   5094  O O     . LEU B 1 133 ? -0.668  25.298  -53.820  1.00 58.25  ? 133 LEU B O     1 
ATOM   5095  C CB    . LEU B 1 133 ? -1.075  22.670  -51.891  1.00 54.84  ? 133 LEU B CB    1 
ATOM   5096  C CG    . LEU B 1 133 ? -2.007  22.350  -53.067  1.00 48.35  ? 133 LEU B CG    1 
ATOM   5097  C CD1   . LEU B 1 133 ? -1.247  21.787  -54.230  1.00 52.69  ? 133 LEU B CD1   1 
ATOM   5098  C CD2   . LEU B 1 133 ? -3.078  21.373  -52.664  1.00 44.11  ? 133 LEU B CD2   1 
ATOM   5099  N N     . TYR B 1 134 ? -1.120  25.901  -51.703  1.00 54.36  ? 134 TYR B N     1 
ATOM   5100  C CA    . TYR B 1 134 ? -1.610  27.219  -52.094  1.00 55.38  ? 134 TYR B CA    1 
ATOM   5101  C C     . TYR B 1 134 ? -0.471  28.002  -52.749  1.00 51.61  ? 134 TYR B C     1 
ATOM   5102  O O     . TYR B 1 134 ? -0.658  28.609  -53.796  1.00 45.22  ? 134 TYR B O     1 
ATOM   5103  C CB    . TYR B 1 134 ? -2.148  27.997  -50.887  1.00 58.07  ? 134 TYR B CB    1 
ATOM   5104  C CG    . TYR B 1 134 ? -2.699  29.379  -51.172  1.00 59.39  ? 134 TYR B CG    1 
ATOM   5105  C CD1   . TYR B 1 134 ? -3.980  29.555  -51.704  1.00 51.70  ? 134 TYR B CD1   1 
ATOM   5106  C CD2   . TYR B 1 134 ? -1.950  30.524  -50.888  1.00 55.02  ? 134 TYR B CD2   1 
ATOM   5107  C CE1   . TYR B 1 134 ? -4.504  30.824  -51.938  1.00 52.89  ? 134 TYR B CE1   1 
ATOM   5108  C CE2   . TYR B 1 134 ? -2.460  31.799  -51.120  1.00 51.06  ? 134 TYR B CE2   1 
ATOM   5109  C CZ    . TYR B 1 134 ? -3.731  31.946  -51.663  1.00 56.62  ? 134 TYR B CZ    1 
ATOM   5110  O OH    . TYR B 1 134 ? -4.219  33.197  -51.938  1.00 58.46  ? 134 TYR B OH    1 
ATOM   5111  N N     . ASP B 1 135 ? 0.715   27.948  -52.125  1.00 51.18  ? 135 ASP B N     1 
ATOM   5112  C CA    . ASP B 1 135 ? 1.855   28.740  -52.554  1.00 55.54  ? 135 ASP B CA    1 
ATOM   5113  C C     . ASP B 1 135 ? 2.321   28.242  -53.920  1.00 56.69  ? 135 ASP B C     1 
ATOM   5114  O O     . ASP B 1 135 ? 2.429   29.042  -54.842  1.00 57.43  ? 135 ASP B O     1 
ATOM   5115  C CB    . ASP B 1 135 ? 2.927   28.806  -51.457  1.00 55.79  ? 135 ASP B CB    1 
ATOM   5116  C CG    . ASP B 1 135 ? 2.561   29.739  -50.300  1.00 55.06  ? 135 ASP B CG    1 
ATOM   5117  O OD1   . ASP B 1 135 ? 1.675   30.610  -50.461  1.00 55.36  ? 135 ASP B OD1   1 
ATOM   5118  O OD2   . ASP B 1 135 ? 3.139   29.570  -49.228  1.00 54.82  ? 135 ASP B OD2   1 
ATOM   5119  N N     . TYR B 1 136 ? 2.484   26.919  -54.074  1.00 57.29  ? 136 TYR B N     1 
ATOM   5120  C CA    . TYR B 1 136 ? 2.836   26.314  -55.351  1.00 49.98  ? 136 TYR B CA    1 
ATOM   5121  C C     . TYR B 1 136 ? 1.865   26.715  -56.460  1.00 55.48  ? 136 TYR B C     1 
ATOM   5122  O O     . TYR B 1 136 ? 2.299   26.862  -57.601  1.00 64.18  ? 136 TYR B O     1 
ATOM   5123  C CB    . TYR B 1 136 ? 2.947   24.799  -55.211  1.00 50.24  ? 136 TYR B CB    1 
ATOM   5124  C CG    . TYR B 1 136 ? 3.290   24.070  -56.485  1.00 59.44  ? 136 TYR B CG    1 
ATOM   5125  C CD1   . TYR B 1 136 ? 2.341   23.881  -57.474  1.00 59.20  ? 136 TYR B CD1   1 
ATOM   5126  C CD2   . TYR B 1 136 ? 4.566   23.584  -56.718  1.00 64.68  ? 136 TYR B CD2   1 
ATOM   5127  C CE1   . TYR B 1 136 ? 2.646   23.224  -58.650  1.00 65.91  ? 136 TYR B CE1   1 
ATOM   5128  C CE2   . TYR B 1 136 ? 4.889   22.923  -57.893  1.00 63.91  ? 136 TYR B CE2   1 
ATOM   5129  C CZ    . TYR B 1 136 ? 3.920   22.735  -58.859  1.00 65.24  ? 136 TYR B CZ    1 
ATOM   5130  O OH    . TYR B 1 136 ? 4.178   22.064  -60.023  1.00 65.21  ? 136 TYR B OH    1 
ATOM   5131  N N     . ILE B 1 137 ? 0.573   26.887  -56.131  1.00 59.69  ? 137 ILE B N     1 
ATOM   5132  C CA    . ILE B 1 137 ? -0.441  27.297  -57.101  1.00 59.43  ? 137 ILE B CA    1 
ATOM   5133  C C     . ILE B 1 137 ? -0.317  28.791  -57.398  1.00 54.72  ? 137 ILE B C     1 
ATOM   5134  O O     . ILE B 1 137 ? -0.408  29.177  -58.562  1.00 57.19  ? 137 ILE B O     1 
ATOM   5135  C CB    . ILE B 1 137 ? -1.878  26.904  -56.661  1.00 60.25  ? 137 ILE B CB    1 
ATOM   5136  C CG1   . ILE B 1 137 ? -2.212  25.456  -57.027  1.00 55.40  ? 137 ILE B CG1   1 
ATOM   5137  C CG2   . ILE B 1 137 ? -2.935  27.834  -57.248  1.00 59.92  ? 137 ILE B CG2   1 
ATOM   5138  C CD1   . ILE B 1 137 ? -3.205  24.787  -56.118  1.00 54.29  ? 137 ILE B CD1   1 
ATOM   5139  N N     . GLN B 1 138 ? -0.114  29.634  -56.376  1.00 54.69  ? 138 GLN B N     1 
ATOM   5140  C CA    . GLN B 1 138 ? -0.033  31.076  -56.610  1.00 59.12  ? 138 GLN B CA    1 
ATOM   5141  C C     . GLN B 1 138 ? 1.167   31.417  -57.496  1.00 62.94  ? 138 GLN B C     1 
ATOM   5142  O O     . GLN B 1 138 ? 0.990   32.154  -58.468  1.00 61.88  ? 138 GLN B O     1 
ATOM   5143  C CB    . GLN B 1 138 ? 0.026   31.893  -55.317  1.00 57.20  ? 138 GLN B CB    1 
ATOM   5144  C CG    . GLN B 1 138 ? -1.286  31.924  -54.533  1.00 71.45  ? 138 GLN B CG    1 
ATOM   5145  C CD    . GLN B 1 138 ? -2.551  32.113  -55.348  1.00 76.75  ? 138 GLN B CD    1 
ATOM   5146  O OE1   . GLN B 1 138 ? -2.812  33.179  -55.900  1.00 77.40  ? 138 GLN B OE1   1 
ATOM   5147  N NE2   . GLN B 1 138 ? -3.378  31.080  -55.402  1.00 78.47  ? 138 GLN B NE2   1 
ATOM   5148  N N     . GLU B 1 139 ? 2.349   30.843  -57.181  1.00 66.32  ? 139 GLU B N     1 
ATOM   5149  C CA    . GLU B 1 139 ? 3.594   31.072  -57.905  1.00 64.51  ? 139 GLU B CA    1 
ATOM   5150  C C     . GLU B 1 139 ? 3.437   30.668  -59.369  1.00 62.08  ? 139 GLU B C     1 
ATOM   5151  O O     . GLU B 1 139 ? 3.835   31.419  -60.249  1.00 71.51  ? 139 GLU B O     1 
ATOM   5152  C CB    . GLU B 1 139 ? 4.774   30.307  -57.290  1.00 79.28  ? 139 GLU B CB    1 
ATOM   5153  C CG    . GLU B 1 139 ? 5.335   30.906  -55.999  1.00 96.08  ? 139 GLU B CG    1 
ATOM   5154  C CD    . GLU B 1 139 ? 6.109   29.942  -55.092  1.00 116.24 ? 139 GLU B CD    1 
ATOM   5155  O OE1   . GLU B 1 139 ? 6.374   30.309  -53.903  1.00 90.93  ? 139 GLU B OE1   1 
ATOM   5156  O OE2   . GLU B 1 139 ? 6.444   28.811  -55.551  1.00 110.81 ? 139 GLU B OE2   1 
ATOM   5157  N N     . LYS B 1 140 ? 2.855   29.495  -59.643  1.00 63.12  ? 140 LYS B N     1 
ATOM   5158  C CA    . LYS B 1 140 ? 2.683   29.052  -61.022  1.00 58.33  ? 140 LYS B CA    1 
ATOM   5159  C C     . LYS B 1 140 ? 1.498   29.746  -61.690  1.00 50.96  ? 140 LYS B C     1 
ATOM   5160  O O     . LYS B 1 140 ? 1.236   29.471  -62.844  1.00 53.52  ? 140 LYS B O     1 
ATOM   5161  C CB    . LYS B 1 140 ? 2.458   27.542  -61.122  1.00 59.59  ? 140 LYS B CB    1 
ATOM   5162  C CG    . LYS B 1 140 ? 3.560   26.660  -60.563  1.00 68.84  ? 140 LYS B CG    1 
ATOM   5163  C CD    . LYS B 1 140 ? 4.846   26.701  -61.349  1.00 77.42  ? 140 LYS B CD    1 
ATOM   5164  C CE    . LYS B 1 140 ? 6.042   26.279  -60.514  1.00 91.17  ? 140 LYS B CE    1 
ATOM   5165  N NZ    . LYS B 1 140 ? 7.318   26.837  -61.027  1.00 88.76  ? 140 LYS B NZ    1 
ATOM   5166  N N     . GLY B 1 141 ? 0.748   30.596  -60.982  1.00 50.78  ? 141 GLY B N     1 
ATOM   5167  C CA    . GLY B 1 141 ? -0.362  31.324  -61.585  1.00 53.03  ? 141 GLY B CA    1 
ATOM   5168  C C     . GLY B 1 141 ? -1.560  30.459  -62.024  1.00 58.78  ? 141 GLY B C     1 
ATOM   5169  O O     . GLY B 1 141 ? -2.448  30.986  -62.694  1.00 52.72  ? 141 GLY B O     1 
ATOM   5170  N N     . LEU B 1 142 ? -1.641  29.178  -61.591  1.00 57.51  ? 142 LEU B N     1 
ATOM   5171  C CA    . LEU B 1 142 ? -2.727  28.249  -61.936  1.00 53.97  ? 142 LEU B CA    1 
ATOM   5172  C C     . LEU B 1 142 ? -4.090  28.734  -61.421  1.00 50.23  ? 142 LEU B C     1 
ATOM   5173  O O     . LEU B 1 142 ? -4.181  29.291  -60.338  1.00 52.55  ? 142 LEU B O     1 
ATOM   5174  C CB    . LEU B 1 142 ? -2.408  26.866  -61.352  1.00 49.93  ? 142 LEU B CB    1 
ATOM   5175  C CG    . LEU B 1 142 ? -1.125  26.211  -61.875  1.00 56.22  ? 142 LEU B CG    1 
ATOM   5176  C CD1   . LEU B 1 142 ? -0.949  24.808  -61.330  1.00 55.03  ? 142 LEU B CD1   1 
ATOM   5177  C CD2   . LEU B 1 142 ? -1.070  26.180  -63.399  1.00 58.82  ? 142 LEU B CD2   1 
ATOM   5178  N N     . LYS B 1 143 ? -5.163  28.500  -62.188  1.00 52.23  ? 143 LYS B N     1 
ATOM   5179  C CA    . LYS B 1 143 ? -6.476  29.058  -61.887  1.00 62.68  ? 143 LYS B CA    1 
ATOM   5180  C C     . LYS B 1 143 ? -7.328  28.050  -61.097  1.00 57.65  ? 143 LYS B C     1 
ATOM   5181  O O     . LYS B 1 143 ? -8.435  27.709  -61.491  1.00 55.51  ? 143 LYS B O     1 
ATOM   5182  C CB    . LYS B 1 143 ? -7.192  29.468  -63.177  1.00 69.52  ? 143 LYS B CB    1 
ATOM   5183  C CG    . LYS B 1 143 ? -6.328  30.106  -64.256  1.00 79.90  ? 143 LYS B CG    1 
ATOM   5184  C CD    . LYS B 1 143 ? -6.671  31.544  -64.620  1.00 95.91  ? 143 LYS B CD    1 
ATOM   5185  C CE    . LYS B 1 143 ? -6.119  31.906  -65.991  1.00 104.07 ? 143 LYS B CE    1 
ATOM   5186  N NZ    . LYS B 1 143 ? -6.691  33.162  -66.527  1.00 104.88 ? 143 LYS B NZ    1 
ATOM   5187  N N     . LEU B 1 144 ? -6.837  27.646  -59.923  1.00 52.02  ? 144 LEU B N     1 
ATOM   5188  C CA    . LEU B 1 144 ? -7.495  26.678  -59.068  1.00 50.00  ? 144 LEU B CA    1 
ATOM   5189  C C     . LEU B 1 144 ? -7.577  27.226  -57.657  1.00 52.73  ? 144 LEU B C     1 
ATOM   5190  O O     . LEU B 1 144 ? -6.670  27.903  -57.206  1.00 58.57  ? 144 LEU B O     1 
ATOM   5191  C CB    . LEU B 1 144 ? -6.650  25.416  -59.027  1.00 44.75  ? 144 LEU B CB    1 
ATOM   5192  C CG    . LEU B 1 144 ? -6.333  24.837  -60.392  1.00 46.12  ? 144 LEU B CG    1 
ATOM   5193  C CD1   . LEU B 1 144 ? -5.254  23.767  -60.262  1.00 42.22  ? 144 LEU B CD1   1 
ATOM   5194  C CD2   . LEU B 1 144 ? -7.609  24.288  -61.031  1.00 42.94  ? 144 LEU B CD2   1 
ATOM   5195  N N     . TRP B 1 145 ? -8.631  26.845  -56.944  1.00 51.79  ? 145 TRP B N     1 
ATOM   5196  C CA    . TRP B 1 145 ? -8.688  27.046  -55.509  1.00 47.58  ? 145 TRP B CA    1 
ATOM   5197  C C     . TRP B 1 145 ? -8.384  25.747  -54.778  1.00 42.19  ? 145 TRP B C     1 
ATOM   5198  O O     . TRP B 1 145 ? -8.526  24.675  -55.355  1.00 47.68  ? 145 TRP B O     1 
ATOM   5199  C CB    . TRP B 1 145 ? -10.056 27.589  -55.151  1.00 46.63  ? 145 TRP B CB    1 
ATOM   5200  C CG    . TRP B 1 145 ? -10.224 29.005  -55.585  1.00 46.30  ? 145 TRP B CG    1 
ATOM   5201  C CD1   . TRP B 1 145 ? -9.342  29.796  -56.267  1.00 42.19  ? 145 TRP B CD1   1 
ATOM   5202  C CD2   . TRP B 1 145 ? -11.353 29.831  -55.253  1.00 50.27  ? 145 TRP B CD2   1 
ATOM   5203  N NE1   . TRP B 1 145 ? -9.876  31.051  -56.417  1.00 44.68  ? 145 TRP B NE1   1 
ATOM   5204  C CE2   . TRP B 1 145 ? -11.091 31.109  -55.788  1.00 46.11  ? 145 TRP B CE2   1 
ATOM   5205  C CE3   . TRP B 1 145 ? -12.542 29.609  -54.537  1.00 48.65  ? 145 TRP B CE3   1 
ATOM   5206  C CZ2   . TRP B 1 145 ? -12.009 32.150  -55.666  1.00 54.59  ? 145 TRP B CZ2   1 
ATOM   5207  C CZ3   . TRP B 1 145 ? -13.450 30.638  -54.421  1.00 51.57  ? 145 TRP B CZ3   1 
ATOM   5208  C CH2   . TRP B 1 145 ? -13.177 31.894  -54.975  1.00 53.63  ? 145 TRP B CH2   1 
ATOM   5209  N N     . ILE B 1 146 ? -7.864  25.847  -53.553  1.00 40.41  ? 146 ILE B N     1 
ATOM   5210  C CA    . ILE B 1 146 ? -7.828  24.687  -52.685  1.00 40.25  ? 146 ILE B CA    1 
ATOM   5211  C C     . ILE B 1 146 ? -8.976  24.888  -51.711  1.00 44.19  ? 146 ILE B C     1 
ATOM   5212  O O     . ILE B 1 146 ? -9.718  25.875  -51.843  1.00 41.69  ? 146 ILE B O     1 
ATOM   5213  C CB    . ILE B 1 146 ? -6.463  24.481  -52.019  1.00 43.25  ? 146 ILE B CB    1 
ATOM   5214  C CG1   . ILE B 1 146 ? -6.110  25.618  -51.069  1.00 52.03  ? 146 ILE B CG1   1 
ATOM   5215  C CG2   . ILE B 1 146 ? -5.390  24.327  -53.083  1.00 46.65  ? 146 ILE B CG2   1 
ATOM   5216  C CD1   . ILE B 1 146 ? -4.961  25.281  -50.161  1.00 55.18  ? 146 ILE B CD1   1 
ATOM   5217  N N     . ASP B 1 147 ? -9.193  23.890  -50.843  1.00 46.29  ? 147 ASP B N     1 
ATOM   5218  C CA    . ASP B 1 147 ? -10.209 24.011  -49.806  1.00 48.34  ? 147 ASP B CA    1 
ATOM   5219  C C     . ASP B 1 147 ? -9.575  23.748  -48.431  1.00 43.41  ? 147 ASP B C     1 
ATOM   5220  O O     . ASP B 1 147 ? -9.018  22.681  -48.192  1.00 41.33  ? 147 ASP B O     1 
ATOM   5221  C CB    . ASP B 1 147 ? -11.407 23.120  -50.126  1.00 50.31  ? 147 ASP B CB    1 
ATOM   5222  C CG    . ASP B 1 147 ? -12.467 23.267  -49.057  1.00 52.36  ? 147 ASP B CG    1 
ATOM   5223  O OD1   . ASP B 1 147 ? -12.156 22.855  -47.909  1.00 43.98  ? 147 ASP B OD1   1 
ATOM   5224  O OD2   . ASP B 1 147 ? -13.560 23.852  -49.366  1.00 48.78  ? 147 ASP B OD2   1 
ATOM   5225  N N     . VAL B 1 148 ? -9.618  24.737  -47.527  1.00 41.55  ? 148 VAL B N     1 
ATOM   5226  C CA    . VAL B 1 148 ? -8.715  24.708  -46.381  1.00 44.65  ? 148 VAL B CA    1 
ATOM   5227  C C     . VAL B 1 148 ? -9.514  24.579  -45.106  1.00 42.73  ? 148 VAL B C     1 
ATOM   5228  O O     . VAL B 1 148 ? -10.556 25.203  -44.942  1.00 46.45  ? 148 VAL B O     1 
ATOM   5229  C CB    . VAL B 1 148 ? -7.788  25.938  -46.280  1.00 43.26  ? 148 VAL B CB    1 
ATOM   5230  C CG1   . VAL B 1 148 ? -6.803  25.987  -47.434  1.00 40.54  ? 148 VAL B CG1   1 
ATOM   5231  C CG2   . VAL B 1 148 ? -8.581  27.244  -46.179  1.00 43.16  ? 148 VAL B CG2   1 
ATOM   5232  N N     . PRO B 1 149 ? -8.972  23.848  -44.126  1.00 51.17  ? 149 PRO B N     1 
ATOM   5233  C CA    . PRO B 1 149 ? -9.423  23.984  -42.743  1.00 57.54  ? 149 PRO B CA    1 
ATOM   5234  C C     . PRO B 1 149 ? -8.915  25.295  -42.160  1.00 59.81  ? 149 PRO B C     1 
ATOM   5235  O O     . PRO B 1 149 ? -8.247  26.063  -42.848  1.00 65.10  ? 149 PRO B O     1 
ATOM   5236  C CB    . PRO B 1 149 ? -8.750  22.788  -42.060  1.00 60.49  ? 149 PRO B CB    1 
ATOM   5237  C CG    . PRO B 1 149 ? -7.469  22.600  -42.839  1.00 58.15  ? 149 PRO B CG    1 
ATOM   5238  C CD    . PRO B 1 149 ? -7.850  22.916  -44.275  1.00 53.97  ? 149 PRO B CD    1 
ATOM   5239  N N     . ASP B 1 150 ? -9.146  25.483  -40.860  1.00 73.39  ? 150 ASP B N     1 
ATOM   5240  C CA    . ASP B 1 150 ? -8.803  26.714  -40.172  1.00 81.95  ? 150 ASP B CA    1 
ATOM   5241  C C     . ASP B 1 150 ? -7.295  26.841  -39.935  1.00 81.44  ? 150 ASP B C     1 
ATOM   5242  O O     . ASP B 1 150 ? -6.792  27.947  -39.768  1.00 87.07  ? 150 ASP B O     1 
ATOM   5243  C CB    . ASP B 1 150 ? -9.605  26.820  -38.877  1.00 88.57  ? 150 ASP B CB    1 
ATOM   5244  C CG    . ASP B 1 150 ? -11.081 27.131  -39.096  1.00 96.90  ? 150 ASP B CG    1 
ATOM   5245  O OD1   . ASP B 1 150 ? -11.365 28.068  -39.910  1.00 85.03  ? 150 ASP B OD1   1 
ATOM   5246  O OD2   . ASP B 1 150 ? -11.941 26.468  -38.419  1.00 78.75  ? 150 ASP B OD2   1 
ATOM   5247  N N     . GLY B 1 151 ? -6.555  25.733  -39.944  1.00 90.01  ? 151 GLY B N     1 
ATOM   5248  C CA    . GLY B 1 151 ? -5.103  25.809  -39.839  1.00 96.75  ? 151 GLY B CA    1 
ATOM   5249  C C     . GLY B 1 151 ? -4.410  25.299  -41.099  1.00 87.12  ? 151 GLY B C     1 
ATOM   5250  O O     . GLY B 1 151 ? -4.392  24.094  -41.345  1.00 91.58  ? 151 GLY B O     1 
ATOM   5251  N N     . GLY B 1 152 ? -3.813  26.222  -41.857  1.00 75.09  ? 152 GLY B N     1 
ATOM   5252  C CA    . GLY B 1 152 ? -3.109  25.898  -43.090  1.00 78.58  ? 152 GLY B CA    1 
ATOM   5253  C C     . GLY B 1 152 ? -1.892  24.985  -42.898  1.00 82.91  ? 152 GLY B C     1 
ATOM   5254  O O     . GLY B 1 152 ? -1.442  24.314  -43.839  1.00 68.48  ? 152 GLY B O     1 
ATOM   5255  N N     . TRP B 1 153 ? -1.305  24.992  -41.695  1.00 88.67  ? 153 TRP B N     1 
ATOM   5256  C CA    . TRP B 1 153 ? -0.486  23.853  -41.327  1.00 99.33  ? 153 TRP B CA    1 
ATOM   5257  C C     . TRP B 1 153 ? -1.489  22.735  -41.036  1.00 88.69  ? 153 TRP B C     1 
ATOM   5258  O O     . TRP B 1 153 ? -2.537  22.929  -40.412  1.00 86.59  ? 153 TRP B O     1 
ATOM   5259  C CB    . TRP B 1 153 ? 0.513   24.136  -40.186  1.00 111.24 ? 153 TRP B CB    1 
ATOM   5260  C CG    . TRP B 1 153 ? 1.600   25.139  -40.472  1.00 131.10 ? 153 TRP B CG    1 
ATOM   5261  C CD1   . TRP B 1 153 ? 1.882   26.228  -39.697  1.00 140.86 ? 153 TRP B CD1   1 
ATOM   5262  C CD2   . TRP B 1 153 ? 2.570   25.171  -41.552  1.00 142.07 ? 153 TRP B CD2   1 
ATOM   5263  N NE1   . TRP B 1 153 ? 2.934   26.937  -40.214  1.00 142.13 ? 153 TRP B NE1   1 
ATOM   5264  C CE2   . TRP B 1 153 ? 3.378   26.318  -41.351  1.00 142.10 ? 153 TRP B CE2   1 
ATOM   5265  C CE3   . TRP B 1 153 ? 2.841   24.372  -42.676  1.00 134.34 ? 153 TRP B CE3   1 
ATOM   5266  C CZ2   . TRP B 1 153 ? 4.418   26.672  -42.216  1.00 133.63 ? 153 TRP B CZ2   1 
ATOM   5267  C CZ3   . TRP B 1 153 ? 3.872   24.717  -43.531  1.00 116.01 ? 153 TRP B CZ3   1 
ATOM   5268  C CH2   . TRP B 1 153 ? 4.646   25.856  -43.303  1.00 131.11 ? 153 TRP B CH2   1 
ATOM   5269  N N     . GLY B 1 154 ? -1.174  21.566  -41.573  1.00 67.63  ? 154 GLY B N     1 
ATOM   5270  C CA    . GLY B 1 154 ? -2.157  20.537  -41.825  1.00 58.54  ? 154 GLY B CA    1 
ATOM   5271  C C     . GLY B 1 154 ? -1.813  19.880  -43.152  1.00 52.56  ? 154 GLY B C     1 
ATOM   5272  O O     . GLY B 1 154 ? -1.386  20.568  -44.083  1.00 51.71  ? 154 GLY B O     1 
ATOM   5273  N N     . SER B 1 155 ? -1.913  18.550  -43.194  1.00 47.16  ? 155 SER B N     1 
ATOM   5274  C CA    . SER B 1 155 ? -1.697  17.804  -44.418  1.00 42.24  ? 155 SER B CA    1 
ATOM   5275  C C     . SER B 1 155 ? -2.997  17.760  -45.228  1.00 49.34  ? 155 SER B C     1 
ATOM   5276  O O     . SER B 1 155 ? -4.041  17.325  -44.730  1.00 45.67  ? 155 SER B O     1 
ATOM   5277  C CB    . SER B 1 155 ? -1.194  16.439  -44.090  1.00 45.64  ? 155 SER B CB    1 
ATOM   5278  O OG    . SER B 1 155 ? -1.138  15.609  -45.256  1.00 57.33  ? 155 SER B OG    1 
ATOM   5279  N N     . VAL B 1 156 ? -2.923  18.218  -46.486  1.00 52.17  ? 156 VAL B N     1 
ATOM   5280  C CA    . VAL B 1 156 ? -3.907  17.884  -47.505  1.00 46.66  ? 156 VAL B CA    1 
ATOM   5281  C C     . VAL B 1 156 ? -4.301  16.408  -47.375  1.00 43.00  ? 156 VAL B C     1 
ATOM   5282  O O     . VAL B 1 156 ? -5.490  16.085  -47.366  1.00 36.84  ? 156 VAL B O     1 
ATOM   5283  C CB    . VAL B 1 156 ? -3.381  18.179  -48.925  1.00 48.43  ? 156 VAL B CB    1 
ATOM   5284  C CG1   . VAL B 1 156 ? -4.400  17.809  -49.986  1.00 57.32  ? 156 VAL B CG1   1 
ATOM   5285  C CG2   . VAL B 1 156 ? -2.983  19.631  -49.096  1.00 50.75  ? 156 VAL B CG2   1 
ATOM   5286  N N     . VAL B 1 157 ? -3.316  15.502  -47.288  1.00 43.92  ? 157 VAL B N     1 
ATOM   5287  C CA    . VAL B 1 157 ? -3.624  14.073  -47.148  1.00 50.86  ? 157 VAL B CA    1 
ATOM   5288  C C     . VAL B 1 157 ? -4.215  13.752  -45.759  1.00 47.34  ? 157 VAL B C     1 
ATOM   5289  O O     . VAL B 1 157 ? -5.351  13.299  -45.646  1.00 52.23  ? 157 VAL B O     1 
ATOM   5290  C CB    . VAL B 1 157 ? -2.393  13.188  -47.443  1.00 52.36  ? 157 VAL B CB    1 
ATOM   5291  C CG1   . VAL B 1 157 ? -2.660  11.727  -47.133  1.00 46.46  ? 157 VAL B CG1   1 
ATOM   5292  C CG2   . VAL B 1 157 ? -1.890  13.345  -48.878  1.00 54.30  ? 157 VAL B CG2   1 
ATOM   5293  N N     . GLY B 1 158 ? -3.425  13.920  -44.694  1.00 49.12  ? 158 GLY B N     1 
ATOM   5294  C CA    . GLY B 1 158 ? -3.835  13.586  -43.335  1.00 46.61  ? 158 GLY B CA    1 
ATOM   5295  C C     . GLY B 1 158 ? -5.250  14.072  -43.003  1.00 44.20  ? 158 GLY B C     1 
ATOM   5296  O O     . GLY B 1 158 ? -6.037  13.345  -42.397  1.00 44.67  ? 158 GLY B O     1 
ATOM   5297  N N     . ASN B 1 159 ? -5.575  15.290  -43.424  1.00 39.37  ? 159 ASN B N     1 
ATOM   5298  C CA    . ASN B 1 159 ? -6.852  15.889  -43.081  1.00 46.15  ? 159 ASN B CA    1 
ATOM   5299  C C     . ASN B 1 159 ? -8.018  15.176  -43.763  1.00 47.68  ? 159 ASN B C     1 
ATOM   5300  O O     . ASN B 1 159 ? -8.972  14.782  -43.121  1.00 49.32  ? 159 ASN B O     1 
ATOM   5301  C CB    . ASN B 1 159 ? -6.902  17.353  -43.483  1.00 44.03  ? 159 ASN B CB    1 
ATOM   5302  C CG    . ASN B 1 159 ? -8.248  17.969  -43.193  1.00 46.23  ? 159 ASN B CG    1 
ATOM   5303  O OD1   . ASN B 1 159 ? -9.183  17.877  -43.984  1.00 55.01  ? 159 ASN B OD1   1 
ATOM   5304  N ND2   . ASN B 1 159 ? -8.338  18.652  -42.074  1.00 50.03  ? 159 ASN B ND2   1 
ATOM   5305  N N     . ALA B 1 160 ? -7.965  15.060  -45.084  1.00 49.56  ? 160 ALA B N     1 
ATOM   5306  C CA    . ALA B 1 160 ? -8.940  14.284  -45.824  1.00 47.53  ? 160 ALA B CA    1 
ATOM   5307  C C     . ALA B 1 160 ? -9.128  12.885  -45.217  1.00 47.44  ? 160 ALA B C     1 
ATOM   5308  O O     . ALA B 1 160 ? -10.255 12.384  -45.117  1.00 42.79  ? 160 ALA B O     1 
ATOM   5309  C CB    . ALA B 1 160 ? -8.475  14.217  -47.263  1.00 47.16  ? 160 ALA B CB    1 
ATOM   5310  N N     . LEU B 1 161 ? -8.028  12.235  -44.817  1.00 43.79  ? 161 LEU B N     1 
ATOM   5311  C CA    . LEU B 1 161 ? -8.103  10.864  -44.332  1.00 44.17  ? 161 LEU B CA    1 
ATOM   5312  C C     . LEU B 1 161 ? -8.851  10.757  -43.003  1.00 43.42  ? 161 LEU B C     1 
ATOM   5313  O O     . LEU B 1 161 ? -9.316  9.683   -42.658  1.00 42.58  ? 161 LEU B O     1 
ATOM   5314  C CB    . LEU B 1 161 ? -6.684  10.326  -44.161  1.00 46.84  ? 161 LEU B CB    1 
ATOM   5315  C CG    . LEU B 1 161 ? -5.915  9.973   -45.433  1.00 47.84  ? 161 LEU B CG    1 
ATOM   5316  C CD1   . LEU B 1 161 ? -4.619  9.272   -45.062  1.00 50.06  ? 161 LEU B CD1   1 
ATOM   5317  C CD2   . LEU B 1 161 ? -6.713  9.075   -46.357  1.00 48.11  ? 161 LEU B CD2   1 
ATOM   5318  N N     . ASP B 1 162 ? -8.906  11.845  -42.224  1.00 43.88  ? 162 ASP B N     1 
ATOM   5319  C CA    . ASP B 1 162 ? -9.638  11.873  -40.970  1.00 42.80  ? 162 ASP B CA    1 
ATOM   5320  C C     . ASP B 1 162 ? -10.991 12.548  -41.186  1.00 39.65  ? 162 ASP B C     1 
ATOM   5321  O O     . ASP B 1 162 ? -11.625 12.937  -40.233  1.00 41.73  ? 162 ASP B O     1 
ATOM   5322  C CB    . ASP B 1 162 ? -8.840  12.587  -39.867  1.00 45.98  ? 162 ASP B CB    1 
ATOM   5323  C CG    . ASP B 1 162 ? -9.027  12.012  -38.462  1.00 56.93  ? 162 ASP B CG    1 
ATOM   5324  O OD1   . ASP B 1 162 ? -8.889  10.745  -38.271  1.00 56.20  ? 162 ASP B OD1   1 
ATOM   5325  O OD2   . ASP B 1 162 ? -9.252  12.828  -37.544  1.00 63.75  ? 162 ASP B OD2   1 
ATOM   5326  N N     . HIS B 1 163 ? -11.434 12.667  -42.438  1.00 40.16  ? 163 HIS B N     1 
ATOM   5327  C CA    . HIS B 1 163 ? -12.783 13.091  -42.793  1.00 38.27  ? 163 HIS B CA    1 
ATOM   5328  C C     . HIS B 1 163 ? -12.920 14.556  -42.421  1.00 38.03  ? 163 HIS B C     1 
ATOM   5329  O O     . HIS B 1 163 ? -13.995 15.020  -42.034  1.00 41.59  ? 163 HIS B O     1 
ATOM   5330  C CB    . HIS B 1 163 ? -13.888 12.167  -42.256  1.00 35.44  ? 163 HIS B CB    1 
ATOM   5331  C CG    . HIS B 1 163 ? -13.812 10.721  -42.684  1.00 40.57  ? 163 HIS B CG    1 
ATOM   5332  N ND1   . HIS B 1 163 ? -14.286 9.690   -41.888  1.00 35.44  ? 163 HIS B ND1   1 
ATOM   5333  C CD2   . HIS B 1 163 ? -13.274 10.117  -43.767  1.00 44.50  ? 163 HIS B CD2   1 
ATOM   5334  C CE1   . HIS B 1 163 ? -14.113 8.528   -42.515  1.00 37.98  ? 163 HIS B CE1   1 
ATOM   5335  N NE2   . HIS B 1 163 ? -13.472 8.752   -43.639  1.00 41.88  ? 163 HIS B NE2   1 
ATOM   5336  N N     . GLY B 1 164 ? -11.851 15.302  -42.694  1.00 37.29  ? 164 GLY B N     1 
ATOM   5337  C CA    . GLY B 1 164 ? -11.802 16.721  -42.372  1.00 39.20  ? 164 GLY B CA    1 
ATOM   5338  C C     . GLY B 1 164 ? -12.600 17.572  -43.347  1.00 40.49  ? 164 GLY B C     1 
ATOM   5339  O O     . GLY B 1 164 ? -12.910 17.086  -44.432  1.00 40.00  ? 164 GLY B O     1 
ATOM   5340  N N     . ILE B 1 165 ? -12.914 18.820  -42.929  1.00 47.50  ? 165 ILE B N     1 
ATOM   5341  C CA    . ILE B 1 165 ? -13.790 19.727  -43.660  1.00 48.81  ? 165 ILE B CA    1 
ATOM   5342  C C     . ILE B 1 165 ? -13.140 21.095  -43.877  1.00 52.58  ? 165 ILE B C     1 
ATOM   5343  O O     . ILE B 1 165 ? -12.202 21.482  -43.194  1.00 59.90  ? 165 ILE B O     1 
ATOM   5344  C CB    . ILE B 1 165 ? -15.150 19.893  -42.964  1.00 56.90  ? 165 ILE B CB    1 
ATOM   5345  C CG1   . ILE B 1 165 ? -15.021 20.531  -41.578  1.00 74.62  ? 165 ILE B CG1   1 
ATOM   5346  C CG2   . ILE B 1 165 ? -15.886 18.569  -42.917  1.00 59.28  ? 165 ILE B CG2   1 
ATOM   5347  C CD1   . ILE B 1 165 ? -16.249 21.338  -41.162  1.00 83.70  ? 165 ILE B CD1   1 
ATOM   5348  N N     . GLY B 1 166 ? -13.665 21.816  -44.871  1.00 53.44  ? 166 GLY B N     1 
ATOM   5349  C CA    . GLY B 1 166 ? -13.349 23.208  -45.125  1.00 43.48  ? 166 GLY B CA    1 
ATOM   5350  C C     . GLY B 1 166 ? -14.618 23.952  -45.509  1.00 37.91  ? 166 GLY B C     1 
ATOM   5351  O O     . GLY B 1 166 ? -15.710 23.525  -45.176  1.00 40.13  ? 166 GLY B O     1 
ATOM   5352  N N     . TYR B 1 167 ? -14.484 25.063  -46.225  1.00 39.41  ? 167 TYR B N     1 
ATOM   5353  C CA    . TYR B 1 167 ? -15.534 26.066  -46.210  1.00 40.02  ? 167 TYR B CA    1 
ATOM   5354  C C     . TYR B 1 167 ? -15.781 26.597  -47.612  1.00 39.20  ? 167 TYR B C     1 
ATOM   5355  O O     . TYR B 1 167 ? -16.431 27.625  -47.749  1.00 39.48  ? 167 TYR B O     1 
ATOM   5356  C CB    . TYR B 1 167 ? -15.197 27.149  -45.175  1.00 44.08  ? 167 TYR B CB    1 
ATOM   5357  C CG    . TYR B 1 167 ? -14.988 26.591  -43.791  1.00 49.97  ? 167 TYR B CG    1 
ATOM   5358  C CD1   . TYR B 1 167 ? -16.066 26.280  -42.970  1.00 51.60  ? 167 TYR B CD1   1 
ATOM   5359  C CD2   . TYR B 1 167 ? -13.717 26.259  -43.345  1.00 49.72  ? 167 TYR B CD2   1 
ATOM   5360  C CE1   . TYR B 1 167 ? -15.889 25.710  -41.719  1.00 49.73  ? 167 TYR B CE1   1 
ATOM   5361  C CE2   . TYR B 1 167 ? -13.520 25.688  -42.098  1.00 54.94  ? 167 TYR B CE2   1 
ATOM   5362  C CZ    . TYR B 1 167 ? -14.609 25.403  -41.283  1.00 58.67  ? 167 TYR B CZ    1 
ATOM   5363  O OH    . TYR B 1 167 ? -14.397 24.832  -40.049  1.00 59.04  ? 167 TYR B OH    1 
ATOM   5364  N N     . THR B 1 168 ? -15.384 25.835  -48.645  1.00 47.34  ? 168 THR B N     1 
ATOM   5365  C CA    . THR B 1 168 ? -15.827 26.112  -50.010  1.00 48.60  ? 168 THR B CA    1 
ATOM   5366  C C     . THR B 1 168 ? -16.770 24.994  -50.469  1.00 44.83  ? 168 THR B C     1 
ATOM   5367  O O     . THR B 1 168 ? -17.017 24.051  -49.734  1.00 45.06  ? 168 THR B O     1 
ATOM   5368  C CB    . THR B 1 168 ? -14.612 26.312  -50.932  1.00 52.61  ? 168 THR B CB    1 
ATOM   5369  O OG1   . THR B 1 168 ? -14.222 25.048  -51.477  1.00 49.22  ? 168 THR B OG1   1 
ATOM   5370  C CG2   . THR B 1 168 ? -13.447 26.977  -50.225  1.00 51.83  ? 168 THR B CG2   1 
ATOM   5371  N N     . PRO B 1 169 ? -17.279 24.986  -51.722  1.00 45.51  ? 169 PRO B N     1 
ATOM   5372  C CA    . PRO B 1 169 ? -18.063 23.847  -52.206  1.00 42.82  ? 169 PRO B CA    1 
ATOM   5373  C C     . PRO B 1 169 ? -17.315 22.516  -52.205  1.00 39.10  ? 169 PRO B C     1 
ATOM   5374  O O     . PRO B 1 169 ? -17.945 21.481  -52.292  1.00 41.91  ? 169 PRO B O     1 
ATOM   5375  C CB    . PRO B 1 169 ? -18.438 24.252  -53.644  1.00 39.64  ? 169 PRO B CB    1 
ATOM   5376  C CG    . PRO B 1 169 ? -18.370 25.772  -53.603  1.00 41.69  ? 169 PRO B CG    1 
ATOM   5377  C CD    . PRO B 1 169 ? -17.155 26.046  -52.739  1.00 42.44  ? 169 PRO B CD    1 
ATOM   5378  N N     . TYR B 1 170 ? -15.982 22.559  -52.130  1.00 37.95  ? 170 TYR B N     1 
ATOM   5379  C CA    . TYR B 1 170 ? -15.134 21.383  -52.045  1.00 39.19  ? 170 TYR B CA    1 
ATOM   5380  C C     . TYR B 1 170 ? -14.827 21.064  -50.574  1.00 39.33  ? 170 TYR B C     1 
ATOM   5381  O O     . TYR B 1 170 ? -13.837 20.420  -50.263  1.00 41.47  ? 170 TYR B O     1 
ATOM   5382  C CB    . TYR B 1 170 ? -13.873 21.557  -52.905  1.00 38.04  ? 170 TYR B CB    1 
ATOM   5383  C CG    . TYR B 1 170 ? -14.074 21.362  -54.390  1.00 40.51  ? 170 TYR B CG    1 
ATOM   5384  C CD1   . TYR B 1 170 ? -15.096 22.017  -55.076  1.00 43.63  ? 170 TYR B CD1   1 
ATOM   5385  C CD2   . TYR B 1 170 ? -13.256 20.510  -55.124  1.00 46.94  ? 170 TYR B CD2   1 
ATOM   5386  C CE1   . TYR B 1 170 ? -15.292 21.847  -56.444  1.00 43.46  ? 170 TYR B CE1   1 
ATOM   5387  C CE2   . TYR B 1 170 ? -13.435 20.331  -56.496  1.00 54.15  ? 170 TYR B CE2   1 
ATOM   5388  C CZ    . TYR B 1 170 ? -14.454 21.011  -57.158  1.00 48.99  ? 170 TYR B CZ    1 
ATOM   5389  O OH    . TYR B 1 170 ? -14.635 20.880  -58.506  1.00 50.98  ? 170 TYR B OH    1 
ATOM   5390  N N     . GLY B 1 171 ? -15.768 21.384  -49.685  1.00 40.11  ? 171 GLY B N     1 
ATOM   5391  C CA    . GLY B 1 171 ? -15.552 21.288  -48.258  1.00 40.73  ? 171 GLY B CA    1 
ATOM   5392  C C     . GLY B 1 171 ? -15.384 19.860  -47.763  1.00 41.46  ? 171 GLY B C     1 
ATOM   5393  O O     . GLY B 1 171 ? -14.675 19.670  -46.787  1.00 44.28  ? 171 GLY B O     1 
ATOM   5394  N N     . ASP B 1 172 ? -16.013 18.867  -48.414  1.00 41.16  ? 172 ASP B N     1 
ATOM   5395  C CA    . ASP B 1 172 ? -15.903 17.500  -47.929  1.00 35.91  ? 172 ASP B CA    1 
ATOM   5396  C C     . ASP B 1 172 ? -14.616 16.871  -48.478  1.00 40.20  ? 172 ASP B C     1 
ATOM   5397  O O     . ASP B 1 172 ? -14.599 16.235  -49.532  1.00 42.06  ? 172 ASP B O     1 
ATOM   5398  C CB    . ASP B 1 172 ? -17.185 16.725  -48.200  1.00 33.51  ? 172 ASP B CB    1 
ATOM   5399  C CG    . ASP B 1 172 ? -17.168 15.311  -47.611  1.00 43.43  ? 172 ASP B CG    1 
ATOM   5400  O OD1   . ASP B 1 172 ? -16.060 14.825  -47.172  1.00 39.34  ? 172 ASP B OD1   1 
ATOM   5401  O OD2   . ASP B 1 172 ? -18.251 14.677  -47.598  1.00 40.33  ? 172 ASP B OD2   1 
ATOM   5402  N N     . HIS B 1 173 ? -13.516 17.001  -47.729  1.00 38.67  ? 173 HIS B N     1 
ATOM   5403  C CA    . HIS B 1 173 ? -12.213 16.796  -48.333  1.00 42.43  ? 173 HIS B CA    1 
ATOM   5404  C C     . HIS B 1 173 ? -12.105 15.368  -48.850  1.00 44.87  ? 173 HIS B C     1 
ATOM   5405  O O     . HIS B 1 173 ? -11.546 15.132  -49.917  1.00 42.16  ? 173 HIS B O     1 
ATOM   5406  C CB    . HIS B 1 173 ? -11.077 17.177  -47.372  1.00 44.29  ? 173 HIS B CB    1 
ATOM   5407  C CG    . HIS B 1 173 ? -11.049 18.628  -46.998  1.00 46.97  ? 173 HIS B CG    1 
ATOM   5408  N ND1   . HIS B 1 173 ? -10.242 19.137  -46.000  1.00 45.50  ? 173 HIS B ND1   1 
ATOM   5409  C CD2   . HIS B 1 173 ? -11.761 19.670  -47.480  1.00 47.23  ? 173 HIS B CD2   1 
ATOM   5410  C CE1   . HIS B 1 173 ? -10.481 20.435  -45.885  1.00 52.34  ? 173 HIS B CE1   1 
ATOM   5411  N NE2   . HIS B 1 173 ? -11.403 20.781  -46.772  1.00 50.75  ? 173 HIS B NE2   1 
ATOM   5412  N N     . PHE B 1 174 ? -12.621 14.404  -48.082  1.00 45.23  ? 174 PHE B N     1 
ATOM   5413  C CA    . PHE B 1 174 ? -12.465 13.014  -48.475  1.00 45.91  ? 174 PHE B CA    1 
ATOM   5414  C C     . PHE B 1 174 ? -13.349 12.660  -49.676  1.00 44.82  ? 174 PHE B C     1 
ATOM   5415  O O     . PHE B 1 174 ? -13.024 11.732  -50.409  1.00 44.33  ? 174 PHE B O     1 
ATOM   5416  C CB    . PHE B 1 174 ? -12.724 12.035  -47.328  1.00 42.25  ? 174 PHE B CB    1 
ATOM   5417  C CG    . PHE B 1 174 ? -12.291 10.650  -47.716  1.00 41.49  ? 174 PHE B CG    1 
ATOM   5418  C CD1   . PHE B 1 174 ? -10.960 10.379  -47.960  1.00 42.54  ? 174 PHE B CD1   1 
ATOM   5419  C CD2   . PHE B 1 174 ? -13.221 9.670   -48.001  1.00 46.96  ? 174 PHE B CD2   1 
ATOM   5420  C CE1   . PHE B 1 174 ? -10.554 9.126   -48.394  1.00 41.91  ? 174 PHE B CE1   1 
ATOM   5421  C CE2   . PHE B 1 174 ? -12.819 8.418   -48.440  1.00 46.86  ? 174 PHE B CE2   1 
ATOM   5422  C CZ    . PHE B 1 174 ? -11.482 8.149   -48.631  1.00 48.46  ? 174 PHE B CZ    1 
ATOM   5423  N N     . ALA B 1 175 ? -14.446 13.392  -49.889  1.00 40.77  ? 175 ALA B N     1 
ATOM   5424  C CA    . ALA B 1 175 ? -15.295 13.168  -51.051  1.00 42.15  ? 175 ALA B CA    1 
ATOM   5425  C C     . ALA B 1 175 ? -14.592 13.603  -52.342  1.00 41.81  ? 175 ALA B C     1 
ATOM   5426  O O     . ALA B 1 175 ? -14.923 13.107  -53.404  1.00 45.38  ? 175 ALA B O     1 
ATOM   5427  C CB    . ALA B 1 175 ? -16.600 13.941  -50.883  1.00 45.39  ? 175 ALA B CB    1 
ATOM   5428  N N     . MET B 1 176 ? -13.668 14.568  -52.241  1.00 42.18  ? 176 MET B N     1 
ATOM   5429  C CA    . MET B 1 176 ? -12.921 15.101  -53.367  1.00 42.87  ? 176 MET B CA    1 
ATOM   5430  C C     . MET B 1 176 ? -11.635 14.313  -53.568  1.00 39.11  ? 176 MET B C     1 
ATOM   5431  O O     . MET B 1 176 ? -10.925 14.543  -54.532  1.00 45.42  ? 176 MET B O     1 
ATOM   5432  C CB    . MET B 1 176 ? -12.565 16.576  -53.159  1.00 40.03  ? 176 MET B CB    1 
ATOM   5433  C CG    . MET B 1 176 ? -13.782 17.459  -52.913  1.00 42.48  ? 176 MET B CG    1 
ATOM   5434  S SD    . MET B 1 176 ? -14.987 17.537  -54.289  1.00 46.47  ? 176 MET B SD    1 
ATOM   5435  C CE    . MET B 1 176 ? -16.232 16.395  -53.704  1.00 53.76  ? 176 MET B CE    1 
ATOM   5436  N N     . GLN B 1 177 ? -11.356 13.349  -52.696  1.00 41.67  ? 177 GLN B N     1 
ATOM   5437  C CA    . GLN B 1 177 ? -10.220 12.459  -52.909  1.00 41.44  ? 177 GLN B CA    1 
ATOM   5438  C C     . GLN B 1 177 ? -10.485 11.547  -54.111  1.00 45.26  ? 177 GLN B C     1 
ATOM   5439  O O     . GLN B 1 177 ? -11.627 11.243  -54.457  1.00 49.29  ? 177 GLN B O     1 
ATOM   5440  C CB    . GLN B 1 177 ? -9.926  11.698  -51.623  1.00 40.00  ? 177 GLN B CB    1 
ATOM   5441  C CG    . GLN B 1 177 ? -8.812  10.678  -51.732  1.00 46.43  ? 177 GLN B CG    1 
ATOM   5442  C CD    . GLN B 1 177 ? -9.234  9.294   -52.171  1.00 44.87  ? 177 GLN B CD    1 
ATOM   5443  O OE1   . GLN B 1 177 ? -10.348 8.835   -51.937  1.00 48.04  ? 177 GLN B OE1   1 
ATOM   5444  N NE2   . GLN B 1 177 ? -8.297  8.580   -52.761  1.00 45.10  ? 177 GLN B NE2   1 
ATOM   5445  N N     . CYS B 1 178 ? -9.407  11.149  -54.784  1.00 43.76  ? 178 CYS B N     1 
ATOM   5446  C CA    . CYS B 1 178 ? -9.510  10.390  -56.013  1.00 42.59  ? 178 CYS B CA    1 
ATOM   5447  C C     . CYS B 1 178 ? -8.165  9.755   -56.340  1.00 43.95  ? 178 CYS B C     1 
ATOM   5448  O O     . CYS B 1 178 ? -7.295  10.410  -56.912  1.00 39.54  ? 178 CYS B O     1 
ATOM   5449  C CB    . CYS B 1 178 ? -9.911  11.275  -57.179  1.00 43.36  ? 178 CYS B CB    1 
ATOM   5450  S SG    . CYS B 1 178 ? -10.239 10.288  -58.659  1.00 47.23  ? 178 CYS B SG    1 
ATOM   5451  N N     . GLY B 1 179 ? -8.019  8.478   -55.955  1.00 40.66  ? 179 GLY B N     1 
ATOM   5452  C CA    . GLY B 1 179 ? -6.837  7.685   -56.236  1.00 33.94  ? 179 GLY B CA    1 
ATOM   5453  C C     . GLY B 1 179 ? -5.849  7.790   -55.088  1.00 34.76  ? 179 GLY B C     1 
ATOM   5454  O O     . GLY B 1 179 ? -5.652  8.869   -54.556  1.00 36.50  ? 179 GLY B O     1 
ATOM   5455  N N     . MET B 1 180 ? -5.285  6.660   -54.665  1.00 38.06  ? 180 MET B N     1 
ATOM   5456  C CA    . MET B 1 180 ? -4.238  6.702   -53.668  1.00 44.11  ? 180 MET B CA    1 
ATOM   5457  C C     . MET B 1 180 ? -3.288  5.518   -53.836  1.00 42.37  ? 180 MET B C     1 
ATOM   5458  O O     . MET B 1 180 ? -3.606  4.507   -54.485  1.00 36.71  ? 180 MET B O     1 
ATOM   5459  C CB    . MET B 1 180 ? -4.812  6.724   -52.248  1.00 47.41  ? 180 MET B CB    1 
ATOM   5460  C CG    . MET B 1 180 ? -5.769  5.598   -51.950  1.00 48.81  ? 180 MET B CG    1 
ATOM   5461  S SD    . MET B 1 180 ? -6.082  5.388   -50.150  1.00 51.13  ? 180 MET B SD    1 
ATOM   5462  C CE    . MET B 1 180 ? -7.097  6.825   -49.781  1.00 52.10  ? 180 MET B CE    1 
ATOM   5463  N N     . GLU B 1 181 ? -2.091  5.712   -53.276  1.00 41.20  ? 181 GLU B N     1 
ATOM   5464  C CA    . GLU B 1 181 ? -1.144  4.635   -53.059  1.00 41.52  ? 181 GLU B CA    1 
ATOM   5465  C C     . GLU B 1 181 ? -1.016  4.394   -51.563  1.00 43.13  ? 181 GLU B C     1 
ATOM   5466  O O     . GLU B 1 181 ? -0.984  5.345   -50.777  1.00 49.67  ? 181 GLU B O     1 
ATOM   5467  C CB    . GLU B 1 181 ? 0.216   5.036   -53.603  1.00 47.97  ? 181 GLU B CB    1 
ATOM   5468  C CG    . GLU B 1 181 ? 1.237   3.914   -53.638  1.00 51.39  ? 181 GLU B CG    1 
ATOM   5469  C CD    . GLU B 1 181 ? 2.569   4.409   -54.177  1.00 59.90  ? 181 GLU B CD    1 
ATOM   5470  O OE1   . GLU B 1 181 ? 2.823   4.227   -55.394  1.00 61.98  ? 181 GLU B OE1   1 
ATOM   5471  O OE2   . GLU B 1 181 ? 3.331   5.023   -53.388  1.00 62.97  ? 181 GLU B OE2   1 
ATOM   5472  N N     . VAL B 1 182 ? -0.892  3.117   -51.205  1.00 41.28  ? 182 VAL B N     1 
ATOM   5473  C CA    . VAL B 1 182 ? -0.972  2.666   -49.830  1.00 43.87  ? 182 VAL B CA    1 
ATOM   5474  C C     . VAL B 1 182 ? 0.084   1.588   -49.622  1.00 45.41  ? 182 VAL B C     1 
ATOM   5475  O O     . VAL B 1 182 ? 0.169   0.632   -50.390  1.00 45.70  ? 182 VAL B O     1 
ATOM   5476  C CB    . VAL B 1 182 ? -2.366  2.101   -49.484  1.00 46.75  ? 182 VAL B CB    1 
ATOM   5477  C CG1   . VAL B 1 182 ? -2.398  1.596   -48.054  1.00 48.34  ? 182 VAL B CG1   1 
ATOM   5478  C CG2   . VAL B 1 182 ? -3.507  3.099   -49.712  1.00 48.04  ? 182 VAL B CG2   1 
ATOM   5479  N N     . VAL B 1 183 ? 0.850   1.704   -48.541  1.00 44.07  ? 183 VAL B N     1 
ATOM   5480  C CA    . VAL B 1 183 ? 1.678   0.600   -48.114  1.00 45.89  ? 183 VAL B CA    1 
ATOM   5481  C C     . VAL B 1 183 ? 0.882   -0.231  -47.121  1.00 44.94  ? 183 VAL B C     1 
ATOM   5482  O O     . VAL B 1 183 ? 0.483   0.266   -46.070  1.00 48.76  ? 183 VAL B O     1 
ATOM   5483  C CB    . VAL B 1 183 ? 2.997   1.104   -47.520  1.00 52.81  ? 183 VAL B CB    1 
ATOM   5484  C CG1   . VAL B 1 183 ? 3.890   -0.055  -47.116  1.00 62.94  ? 183 VAL B CG1   1 
ATOM   5485  C CG2   . VAL B 1 183 ? 3.712   2.021   -48.495  1.00 54.24  ? 183 VAL B CG2   1 
ATOM   5486  N N     . LEU B 1 184 ? 0.631   -1.486  -47.489  1.00 46.61  ? 184 LEU B N     1 
ATOM   5487  C CA    . LEU B 1 184 ? -0.113  -2.407  -46.647  1.00 54.76  ? 184 LEU B CA    1 
ATOM   5488  C C     . LEU B 1 184 ? 0.745   -2.826  -45.443  1.00 53.75  ? 184 LEU B C     1 
ATOM   5489  O O     . LEU B 1 184 ? 1.971   -2.719  -45.443  1.00 53.90  ? 184 LEU B O     1 
ATOM   5490  C CB    . LEU B 1 184 ? -0.522  -3.628  -47.485  1.00 61.92  ? 184 LEU B CB    1 
ATOM   5491  C CG    . LEU B 1 184 ? -1.273  -3.372  -48.795  1.00 57.25  ? 184 LEU B CG    1 
ATOM   5492  C CD1   . LEU B 1 184 ? -1.803  -4.693  -49.372  1.00 54.45  ? 184 LEU B CD1   1 
ATOM   5493  C CD2   . LEU B 1 184 ? -2.406  -2.388  -48.575  1.00 56.63  ? 184 LEU B CD2   1 
ATOM   5494  N N     . PRO B 1 185 ? 0.137   -3.334  -44.358  1.00 54.77  ? 185 PRO B N     1 
ATOM   5495  C CA    . PRO B 1 185 ? 0.893   -3.722  -43.169  1.00 57.67  ? 185 PRO B CA    1 
ATOM   5496  C C     . PRO B 1 185 ? 2.010   -4.735  -43.379  1.00 58.94  ? 185 PRO B C     1 
ATOM   5497  O O     . PRO B 1 185 ? 2.864   -4.865  -42.514  1.00 55.46  ? 185 PRO B O     1 
ATOM   5498  C CB    . PRO B 1 185 ? -0.167  -4.364  -42.267  1.00 57.69  ? 185 PRO B CB    1 
ATOM   5499  C CG    . PRO B 1 185 ? -1.456  -3.710  -42.687  1.00 59.70  ? 185 PRO B CG    1 
ATOM   5500  C CD    . PRO B 1 185 ? -1.307  -3.514  -44.181  1.00 58.95  ? 185 PRO B CD    1 
ATOM   5501  N N     . ASN B 1 186 ? 1.985   -5.464  -44.503  1.00 58.70  ? 186 ASN B N     1 
ATOM   5502  C CA    . ASN B 1 186 ? 3.010   -6.455  -44.795  1.00 57.48  ? 186 ASN B CA    1 
ATOM   5503  C C     . ASN B 1 186 ? 4.170   -5.848  -45.588  1.00 59.10  ? 186 ASN B C     1 
ATOM   5504  O O     . ASN B 1 186 ? 5.189   -6.509  -45.785  1.00 65.16  ? 186 ASN B O     1 
ATOM   5505  C CB    . ASN B 1 186 ? 2.440   -7.655  -45.553  1.00 57.77  ? 186 ASN B CB    1 
ATOM   5506  C CG    . ASN B 1 186 ? 1.990   -7.315  -46.955  1.00 58.83  ? 186 ASN B CG    1 
ATOM   5507  O OD1   . ASN B 1 186 ? 2.004   -6.145  -47.339  1.00 68.02  ? 186 ASN B OD1   1 
ATOM   5508  N ND2   . ASN B 1 186 ? 1.558   -8.317  -47.704  1.00 54.75  ? 186 ASN B ND2   1 
ATOM   5509  N N     . GLY B 1 187 ? 4.009   -4.616  -46.082  1.00 56.43  ? 187 GLY B N     1 
ATOM   5510  C CA    . GLY B 1 187 ? 5.094   -3.942  -46.776  1.00 58.07  ? 187 GLY B CA    1 
ATOM   5511  C C     . GLY B 1 187 ? 4.874   -3.765  -48.282  1.00 55.77  ? 187 GLY B C     1 
ATOM   5512  O O     . GLY B 1 187 ? 5.538   -2.944  -48.897  1.00 56.62  ? 187 GLY B O     1 
ATOM   5513  N N     . GLU B 1 188 ? 3.919   -4.494  -48.868  1.00 58.69  ? 188 GLU B N     1 
ATOM   5514  C CA    . GLU B 1 188 ? 3.616   -4.384  -50.292  1.00 60.46  ? 188 GLU B CA    1 
ATOM   5515  C C     . GLU B 1 188 ? 2.899   -3.057  -50.585  1.00 53.02  ? 188 GLU B C     1 
ATOM   5516  O O     . GLU B 1 188 ? 2.205   -2.526  -49.726  1.00 60.76  ? 188 GLU B O     1 
ATOM   5517  C CB    . GLU B 1 188 ? 2.787   -5.597  -50.740  1.00 57.83  ? 188 GLU B CB    1 
ATOM   5518  C CG    . GLU B 1 188 ? 3.430   -6.944  -50.416  1.00 67.74  ? 188 GLU B CG    1 
ATOM   5519  C CD    . GLU B 1 188 ? 4.828   -7.202  -50.963  1.00 76.57  ? 188 GLU B CD    1 
ATOM   5520  O OE1   . GLU B 1 188 ? 4.972   -7.276  -52.198  1.00 81.21  ? 188 GLU B OE1   1 
ATOM   5521  O OE2   . GLU B 1 188 ? 5.773   -7.350  -50.150  1.00 90.08  ? 188 GLU B OE2   1 
ATOM   5522  N N     . VAL B 1 189 ? 3.033   -2.541  -51.815  1.00 52.26  ? 189 VAL B N     1 
ATOM   5523  C CA    . VAL B 1 189 ? 2.422   -1.272  -52.201  1.00 52.98  ? 189 VAL B CA    1 
ATOM   5524  C C     . VAL B 1 189 ? 1.311   -1.553  -53.204  1.00 48.25  ? 189 VAL B C     1 
ATOM   5525  O O     . VAL B 1 189 ? 1.439   -2.477  -53.983  1.00 57.67  ? 189 VAL B O     1 
ATOM   5526  C CB    . VAL B 1 189 ? 3.469   -0.278  -52.750  1.00 49.84  ? 189 VAL B CB    1 
ATOM   5527  C CG1   . VAL B 1 189 ? 4.110   -0.781  -54.020  1.00 48.16  ? 189 VAL B CG1   1 
ATOM   5528  C CG2   . VAL B 1 189 ? 2.891   1.115   -52.971  1.00 50.55  ? 189 VAL B CG2   1 
ATOM   5529  N N     . VAL B 1 190 ? 0.204   -0.795  -53.130  1.00 53.32  ? 190 VAL B N     1 
ATOM   5530  C CA    . VAL B 1 190 ? -0.980  -0.987  -53.972  1.00 52.75  ? 190 VAL B CA    1 
ATOM   5531  C C     . VAL B 1 190 ? -1.510  0.375   -54.387  1.00 48.22  ? 190 VAL B C     1 
ATOM   5532  O O     . VAL B 1 190 ? -1.423  1.323   -53.625  1.00 47.24  ? 190 VAL B O     1 
ATOM   5533  C CB    . VAL B 1 190 ? -2.134  -1.722  -53.269  1.00 54.76  ? 190 VAL B CB    1 
ATOM   5534  C CG1   . VAL B 1 190 ? -1.775  -3.163  -52.942  1.00 65.30  ? 190 VAL B CG1   1 
ATOM   5535  C CG2   . VAL B 1 190 ? -2.606  -0.975  -52.022  1.00 55.77  ? 190 VAL B CG2   1 
ATOM   5536  N N     . ARG B 1 191 ? -2.112  0.433   -55.568  1.00 43.12  ? 191 ARG B N     1 
ATOM   5537  C CA    . ARG B 1 191 ? -2.767  1.635   -56.016  1.00 43.23  ? 191 ARG B CA    1 
ATOM   5538  C C     . ARG B 1 191 ? -4.243  1.345   -56.277  1.00 45.81  ? 191 ARG B C     1 
ATOM   5539  O O     . ARG B 1 191 ? -4.585  0.329   -56.904  1.00 41.42  ? 191 ARG B O     1 
ATOM   5540  C CB    . ARG B 1 191 ? -2.047  2.133   -57.259  1.00 47.77  ? 191 ARG B CB    1 
ATOM   5541  C CG    . ARG B 1 191 ? -0.690  2.731   -56.949  1.00 49.44  ? 191 ARG B CG    1 
ATOM   5542  C CD    . ARG B 1 191 ? -0.124  3.528   -58.099  1.00 53.91  ? 191 ARG B CD    1 
ATOM   5543  N NE    . ARG B 1 191 ? 1.253   3.872   -57.793  1.00 60.05  ? 191 ARG B NE    1 
ATOM   5544  C CZ    . ARG B 1 191 ? 2.036   4.622   -58.550  1.00 60.41  ? 191 ARG B CZ    1 
ATOM   5545  N NH1   . ARG B 1 191 ? 1.571   5.202   -59.638  1.00 70.71  ? 191 ARG B NH1   1 
ATOM   5546  N NH2   . ARG B 1 191 ? 3.273   4.848   -58.167  1.00 59.85  ? 191 ARG B NH2   1 
ATOM   5547  N N     . THR B 1 192 ? -5.097  2.267   -55.799  1.00 43.29  ? 192 THR B N     1 
ATOM   5548  C CA    . THR B 1 192 ? -6.541  2.138   -55.965  1.00 41.03  ? 192 THR B CA    1 
ATOM   5549  C C     . THR B 1 192 ? -6.978  2.766   -57.280  1.00 40.68  ? 192 THR B C     1 
ATOM   5550  O O     . THR B 1 192 ? -6.205  3.513   -57.887  1.00 40.61  ? 192 THR B O     1 
ATOM   5551  C CB    . THR B 1 192 ? -7.338  2.886   -54.901  1.00 36.24  ? 192 THR B CB    1 
ATOM   5552  O OG1   . THR B 1 192 ? -6.962  4.243   -55.156  1.00 34.70  ? 192 THR B OG1   1 
ATOM   5553  C CG2   . THR B 1 192 ? -7.042  2.425   -53.489  1.00 39.04  ? 192 THR B CG2   1 
ATOM   5554  N N     . GLY B 1 193 ? -8.228  2.469   -57.667  1.00 35.50  ? 193 GLY B N     1 
ATOM   5555  C CA    . GLY B 1 193 ? -8.844  3.103   -58.813  1.00 41.44  ? 193 GLY B CA    1 
ATOM   5556  C C     . GLY B 1 193 ? -8.129  2.738   -60.121  1.00 45.06  ? 193 GLY B C     1 
ATOM   5557  O O     . GLY B 1 193 ? -7.650  1.604   -60.292  1.00 43.85  ? 193 GLY B O     1 
ATOM   5558  N N     . MET B 1 194 ? -8.053  3.740   -61.007  1.00 40.64  ? 194 MET B N     1 
ATOM   5559  C CA    . MET B 1 194 ? -7.422  3.619   -62.307  1.00 44.95  ? 194 MET B CA    1 
ATOM   5560  C C     . MET B 1 194 ? -5.898  3.490   -62.161  1.00 46.81  ? 194 MET B C     1 
ATOM   5561  O O     . MET B 1 194 ? -5.214  3.100   -63.105  1.00 43.70  ? 194 MET B O     1 
ATOM   5562  C CB    . MET B 1 194 ? -7.733  4.860   -63.158  1.00 48.55  ? 194 MET B CB    1 
ATOM   5563  C CG    . MET B 1 194 ? -9.195  5.062   -63.452  1.00 49.40  ? 194 MET B CG    1 
ATOM   5564  S SD    . MET B 1 194 ? -9.999  3.550   -64.024  1.00 55.06  ? 194 MET B SD    1 
ATOM   5565  C CE    . MET B 1 194 ? -9.039  3.155   -65.482  1.00 56.65  ? 194 MET B CE    1 
ATOM   5566  N N     . GLY B 1 195 ? -5.347  3.799   -60.983  1.00 43.05  ? 195 GLY B N     1 
ATOM   5567  C CA    . GLY B 1 195 ? -3.916  3.690   -60.794  1.00 42.18  ? 195 GLY B CA    1 
ATOM   5568  C C     . GLY B 1 195 ? -3.454  2.236   -60.769  1.00 46.12  ? 195 GLY B C     1 
ATOM   5569  O O     . GLY B 1 195 ? -2.248  1.974   -60.822  1.00 54.59  ? 195 GLY B O     1 
ATOM   5570  N N     . ALA B 1 196 ? -4.404  1.294   -60.685  1.00 42.66  ? 196 ALA B N     1 
ATOM   5571  C CA    . ALA B 1 196 ? -4.052  -0.120  -60.763  1.00 47.61  ? 196 ALA B CA    1 
ATOM   5572  C C     . ALA B 1 196 ? -3.849  -0.560  -62.219  1.00 51.41  ? 196 ALA B C     1 
ATOM   5573  O O     . ALA B 1 196 ? -3.540  -1.722  -62.483  1.00 47.33  ? 196 ALA B O     1 
ATOM   5574  C CB    . ALA B 1 196 ? -5.089  -0.981  -60.083  1.00 44.80  ? 196 ALA B CB    1 
ATOM   5575  N N     . MET B 1 197 ? -4.035  0.364   -63.162  1.00 50.90  ? 197 MET B N     1 
ATOM   5576  C CA    . MET B 1 197 ? -3.896  0.061   -64.576  1.00 55.06  ? 197 MET B CA    1 
ATOM   5577  C C     . MET B 1 197 ? -2.635  0.744   -65.119  1.00 57.98  ? 197 MET B C     1 
ATOM   5578  O O     . MET B 1 197 ? -2.501  1.982   -65.128  1.00 49.35  ? 197 MET B O     1 
ATOM   5579  C CB    . MET B 1 197 ? -5.139  0.511   -65.350  1.00 55.36  ? 197 MET B CB    1 
ATOM   5580  C CG    . MET B 1 197 ? -4.831  1.247   -66.621  1.00 58.03  ? 197 MET B CG    1 
ATOM   5581  S SD    . MET B 1 197 ? -5.973  0.855   -67.919  1.00 63.71  ? 197 MET B SD    1 
ATOM   5582  C CE    . MET B 1 197 ? -5.775  -0.928  -67.996  1.00 61.70  ? 197 MET B CE    1 
ATOM   5583  N N     . PRO B 1 198 ? -1.656  -0.062  -65.582  1.00 53.31  ? 198 PRO B N     1 
ATOM   5584  C CA    . PRO B 1 198 ? -0.468  0.472   -66.232  1.00 50.90  ? 198 PRO B CA    1 
ATOM   5585  C C     . PRO B 1 198 ? -0.838  1.371   -67.400  1.00 50.03  ? 198 PRO B C     1 
ATOM   5586  O O     . PRO B 1 198 ? -1.699  1.001   -68.193  1.00 48.89  ? 198 PRO B O     1 
ATOM   5587  C CB    . PRO B 1 198 ? 0.197   -0.778  -66.802  1.00 56.25  ? 198 PRO B CB    1 
ATOM   5588  C CG    . PRO B 1 198 ? -0.240  -1.890  -65.882  1.00 56.46  ? 198 PRO B CG    1 
ATOM   5589  C CD    . PRO B 1 198 ? -1.671  -1.532  -65.545  1.00 55.64  ? 198 PRO B CD    1 
ATOM   5590  N N     . GLY B 1 199 ? -0.204  2.544   -67.478  1.00 45.86  ? 199 GLY B N     1 
ATOM   5591  C CA    . GLY B 1 199 ? -0.302  3.378   -68.663  1.00 50.94  ? 199 GLY B CA    1 
ATOM   5592  C C     . GLY B 1 199 ? -1.480  4.332   -68.612  1.00 50.34  ? 199 GLY B C     1 
ATOM   5593  O O     . GLY B 1 199 ? -1.707  5.098   -69.540  1.00 52.71  ? 199 GLY B O     1 
ATOM   5594  N N     . ASN B 1 200 ? -2.203  4.317   -67.497  1.00 56.55  ? 200 ASN B N     1 
ATOM   5595  C CA    . ASN B 1 200 ? -3.377  5.163   -67.375  1.00 53.96  ? 200 ASN B CA    1 
ATOM   5596  C C     . ASN B 1 200 ? -2.959  6.624   -67.254  1.00 49.94  ? 200 ASN B C     1 
ATOM   5597  O O     . ASN B 1 200 ? -1.856  6.932   -66.810  1.00 56.21  ? 200 ASN B O     1 
ATOM   5598  C CB    . ASN B 1 200 ? -4.234  4.760   -66.173  1.00 50.86  ? 200 ASN B CB    1 
ATOM   5599  C CG    . ASN B 1 200 ? -3.685  5.281   -64.866  1.00 47.70  ? 200 ASN B CG    1 
ATOM   5600  O OD1   . ASN B 1 200 ? -3.982  6.412   -64.487  1.00 49.58  ? 200 ASN B OD1   1 
ATOM   5601  N ND2   . ASN B 1 200 ? -2.915  4.454   -64.171  1.00 46.40  ? 200 ASN B ND2   1 
ATOM   5602  N N     . ASN B 1 201 ? -3.898  7.511   -67.586  1.00 49.16  ? 201 ASN B N     1 
ATOM   5603  C CA    . ASN B 1 201 ? -3.783  8.920   -67.280  1.00 47.11  ? 201 ASN B CA    1 
ATOM   5604  C C     . ASN B 1 201 ? -5.071  9.356   -66.598  1.00 45.99  ? 201 ASN B C     1 
ATOM   5605  O O     . ASN B 1 201 ? -5.524  10.484  -66.791  1.00 49.91  ? 201 ASN B O     1 
ATOM   5606  C CB    . ASN B 1 201 ? -3.466  9.724   -68.542  1.00 51.38  ? 201 ASN B CB    1 
ATOM   5607  C CG    . ASN B 1 201 ? -2.060  9.455   -69.054  1.00 55.09  ? 201 ASN B CG    1 
ATOM   5608  O OD1   . ASN B 1 201 ? -1.872  8.801   -70.076  1.00 58.93  ? 201 ASN B OD1   1 
ATOM   5609  N ND2   . ASN B 1 201 ? -1.051  9.941   -68.354  1.00 60.69  ? 201 ASN B ND2   1 
ATOM   5610  N N     . THR B 1 202 ? -5.645  8.458   -65.785  1.00 44.92  ? 202 THR B N     1 
ATOM   5611  C CA    . THR B 1 202 ? -6.985  8.687   -65.260  1.00 47.23  ? 202 THR B CA    1 
ATOM   5612  C C     . THR B 1 202 ? -7.097  8.465   -63.755  1.00 45.98  ? 202 THR B C     1 
ATOM   5613  O O     . THR B 1 202 ? -8.212  8.486   -63.243  1.00 53.36  ? 202 THR B O     1 
ATOM   5614  C CB    . THR B 1 202 ? -8.006  7.794   -65.962  1.00 38.41  ? 202 THR B CB    1 
ATOM   5615  O OG1   . THR B 1 202 ? -7.388  6.519   -66.029  1.00 39.24  ? 202 THR B OG1   1 
ATOM   5616  C CG2   . THR B 1 202 ? -8.366  8.306   -67.329  1.00 40.62  ? 202 THR B CG2   1 
ATOM   5617  N N     . TRP B 1 203 ? -5.955  8.356   -63.063  1.00 48.34  ? 203 TRP B N     1 
ATOM   5618  C CA    . TRP B 1 203 ? -5.878  8.155   -61.615  1.00 46.28  ? 203 TRP B CA    1 
ATOM   5619  C C     . TRP B 1 203 ? -6.690  9.179   -60.830  1.00 43.99  ? 203 TRP B C     1 
ATOM   5620  O O     . TRP B 1 203 ? -7.312  8.818   -59.830  1.00 44.80  ? 203 TRP B O     1 
ATOM   5621  C CB    . TRP B 1 203 ? -4.432  8.218   -61.117  1.00 46.84  ? 203 TRP B CB    1 
ATOM   5622  C CG    . TRP B 1 203 ? -4.175  7.406   -59.889  1.00 48.91  ? 203 TRP B CG    1 
ATOM   5623  C CD1   . TRP B 1 203 ? -5.035  6.573   -59.233  1.00 49.37  ? 203 TRP B CD1   1 
ATOM   5624  C CD2   . TRP B 1 203 ? -2.932  7.334   -59.181  1.00 57.07  ? 203 TRP B CD2   1 
ATOM   5625  N NE1   . TRP B 1 203 ? -4.415  6.001   -58.155  1.00 51.74  ? 203 TRP B NE1   1 
ATOM   5626  C CE2   . TRP B 1 203 ? -3.123  6.442   -58.104  1.00 59.67  ? 203 TRP B CE2   1 
ATOM   5627  C CE3   . TRP B 1 203 ? -1.682  7.935   -59.357  1.00 55.25  ? 203 TRP B CE3   1 
ATOM   5628  C CZ2   . TRP B 1 203 ? -2.097  6.132   -57.216  1.00 61.95  ? 203 TRP B CZ2   1 
ATOM   5629  C CZ3   . TRP B 1 203 ? -0.663  7.615   -58.493  1.00 59.99  ? 203 TRP B CZ3   1 
ATOM   5630  C CH2   . TRP B 1 203 ? -0.879  6.744   -57.424  1.00 67.81  ? 203 TRP B CH2   1 
ATOM   5631  N N     . GLN B 1 204 ? -6.648  10.440  -61.264  1.00 38.01  ? 204 GLN B N     1 
ATOM   5632  C CA    . GLN B 1 204 ? -7.260  11.518  -60.521  1.00 40.28  ? 204 GLN B CA    1 
ATOM   5633  C C     . GLN B 1 204 ? -8.523  11.941  -61.253  1.00 37.86  ? 204 GLN B C     1 
ATOM   5634  O O     . GLN B 1 204 ? -9.045  13.039  -61.035  1.00 37.26  ? 204 GLN B O     1 
ATOM   5635  C CB    . GLN B 1 204 ? -6.260  12.671  -60.366  1.00 41.54  ? 204 GLN B CB    1 
ATOM   5636  C CG    . GLN B 1 204 ? -5.344  12.526  -59.162  1.00 36.88  ? 204 GLN B CG    1 
ATOM   5637  C CD    . GLN B 1 204 ? -4.494  11.288  -59.258  1.00 42.37  ? 204 GLN B CD    1 
ATOM   5638  O OE1   . GLN B 1 204 ? -3.493  11.219  -59.973  1.00 47.14  ? 204 GLN B OE1   1 
ATOM   5639  N NE2   . GLN B 1 204 ? -4.875  10.281  -58.500  1.00 50.38  ? 204 GLN B NE2   1 
ATOM   5640  N N     . LEU B 1 205 ? -9.002  11.072  -62.145  1.00 37.28  ? 205 LEU B N     1 
ATOM   5641  C CA    . LEU B 1 205 ? -10.092 11.476  -63.026  1.00 41.21  ? 205 LEU B CA    1 
ATOM   5642  C C     . LEU B 1 205 ? -11.370 10.701  -62.751  1.00 37.93  ? 205 LEU B C     1 
ATOM   5643  O O     . LEU B 1 205 ? -12.434 11.225  -63.025  1.00 40.29  ? 205 LEU B O     1 
ATOM   5644  C CB    . LEU B 1 205 ? -9.643  11.300  -64.477  1.00 46.25  ? 205 LEU B CB    1 
ATOM   5645  C CG    . LEU B 1 205 ? -8.618  12.330  -64.941  1.00 54.00  ? 205 LEU B CG    1 
ATOM   5646  C CD1   . LEU B 1 205 ? -8.399  12.270  -66.450  1.00 61.87  ? 205 LEU B CD1   1 
ATOM   5647  C CD2   . LEU B 1 205 ? -9.052  13.724  -64.526  1.00 57.27  ? 205 LEU B CD2   1 
ATOM   5648  N N     . PHE B 1 206 ? -11.247 9.471   -62.236  1.00 40.44  ? 206 PHE B N     1 
ATOM   5649  C CA    . PHE B 1 206 ? -12.375 8.601   -61.971  1.00 40.14  ? 206 PHE B CA    1 
ATOM   5650  C C     . PHE B 1 206 ? -12.081 7.762   -60.719  1.00 45.84  ? 206 PHE B C     1 
ATOM   5651  O O     . PHE B 1 206 ? -11.048 7.073   -60.650  1.00 44.26  ? 206 PHE B O     1 
ATOM   5652  C CB    . PHE B 1 206 ? -12.610 7.772   -63.231  1.00 42.64  ? 206 PHE B CB    1 
ATOM   5653  C CG    . PHE B 1 206 ? -13.734 6.767   -63.153  1.00 43.61  ? 206 PHE B CG    1 
ATOM   5654  C CD1   . PHE B 1 206 ? -15.056 7.185   -63.236  1.00 39.30  ? 206 PHE B CD1   1 
ATOM   5655  C CD2   . PHE B 1 206 ? -13.467 5.405   -63.012  1.00 44.45  ? 206 PHE B CD2   1 
ATOM   5656  C CE1   . PHE B 1 206 ? -16.094 6.268   -63.140  1.00 38.56  ? 206 PHE B CE1   1 
ATOM   5657  C CE2   . PHE B 1 206 ? -14.505 4.490   -62.919  1.00 40.48  ? 206 PHE B CE2   1 
ATOM   5658  C CZ    . PHE B 1 206 ? -15.815 4.926   -62.996  1.00 40.06  ? 206 PHE B CZ    1 
ATOM   5659  N N     . LYS B 1 207 ? -12.988 7.841   -59.720  1.00 48.85  ? 207 LYS B N     1 
ATOM   5660  C CA    . LYS B 1 207 ? -12.738 7.305   -58.385  1.00 43.38  ? 207 LYS B CA    1 
ATOM   5661  C C     . LYS B 1 207 ? -12.669 5.775   -58.376  1.00 50.41  ? 207 LYS B C     1 
ATOM   5662  O O     . LYS B 1 207 ? -11.789 5.202   -57.733  1.00 58.44  ? 207 LYS B O     1 
ATOM   5663  C CB    . LYS B 1 207 ? -13.838 7.722   -57.416  1.00 43.10  ? 207 LYS B CB    1 
ATOM   5664  C CG    . LYS B 1 207 ? -13.824 9.165   -56.922  1.00 42.93  ? 207 LYS B CG    1 
ATOM   5665  C CD    . LYS B 1 207 ? -14.998 9.438   -56.010  1.00 44.64  ? 207 LYS B CD    1 
ATOM   5666  C CE    . LYS B 1 207 ? -14.876 10.689  -55.162  1.00 49.49  ? 207 LYS B CE    1 
ATOM   5667  N NZ    . LYS B 1 207 ? -14.089 10.425  -53.926  1.00 49.76  ? 207 LYS B NZ    1 
ATOM   5668  N N     . TYR B 1 208 ? -13.587 5.109   -59.096  1.00 54.08  ? 208 TYR B N     1 
ATOM   5669  C CA    . TYR B 1 208 ? -13.907 3.713   -58.815  1.00 51.47  ? 208 TYR B CA    1 
ATOM   5670  C C     . TYR B 1 208 ? -12.823 2.761   -59.323  1.00 51.92  ? 208 TYR B C     1 
ATOM   5671  O O     . TYR B 1 208 ? -12.457 1.792   -58.659  1.00 54.59  ? 208 TYR B O     1 
ATOM   5672  C CB    . TYR B 1 208 ? -15.272 3.334   -59.401  1.00 49.16  ? 208 TYR B CB    1 
ATOM   5673  C CG    . TYR B 1 208 ? -16.438 4.159   -58.904  1.00 57.24  ? 208 TYR B CG    1 
ATOM   5674  C CD1   . TYR B 1 208 ? -16.649 4.373   -57.546  1.00 64.21  ? 208 TYR B CD1   1 
ATOM   5675  C CD2   . TYR B 1 208 ? -17.330 4.754   -59.782  1.00 60.83  ? 208 TYR B CD2   1 
ATOM   5676  C CE1   . TYR B 1 208 ? -17.715 5.127   -57.073  1.00 61.39  ? 208 TYR B CE1   1 
ATOM   5677  C CE2   . TYR B 1 208 ? -18.411 5.496   -59.327  1.00 69.99  ? 208 TYR B CE2   1 
ATOM   5678  C CZ    . TYR B 1 208 ? -18.614 5.677   -57.968  1.00 66.85  ? 208 TYR B CZ    1 
ATOM   5679  O OH    . TYR B 1 208 ? -19.666 6.431   -57.519  1.00 56.38  ? 208 TYR B OH    1 
ATOM   5680  N N     . GLY B 1 209 ? -12.307 3.013   -60.520  1.00 47.18  ? 209 GLY B N     1 
ATOM   5681  C CA    . GLY B 1 209 ? -11.691 1.934   -61.259  1.00 43.18  ? 209 GLY B CA    1 
ATOM   5682  C C     . GLY B 1 209 ? -12.708 0.817   -61.489  1.00 44.05  ? 209 GLY B C     1 
ATOM   5683  O O     . GLY B 1 209 ? -13.849 1.065   -61.864  1.00 49.74  ? 209 GLY B O     1 
ATOM   5684  N N     . TYR B 1 210 ? -12.308 -0.409  -61.202  1.00 39.75  ? 210 TYR B N     1 
ATOM   5685  C CA    . TYR B 1 210 ? -13.149 -1.557  -61.457  1.00 39.13  ? 210 TYR B CA    1 
ATOM   5686  C C     . TYR B 1 210 ? -13.150 -2.406  -60.197  1.00 39.81  ? 210 TYR B C     1 
ATOM   5687  O O     . TYR B 1 210 ? -12.098 -2.654  -59.638  1.00 42.52  ? 210 TYR B O     1 
ATOM   5688  C CB    . TYR B 1 210 ? -12.603 -2.359  -62.645  1.00 36.86  ? 210 TYR B CB    1 
ATOM   5689  C CG    . TYR B 1 210 ? -13.247 -3.706  -62.848  1.00 37.66  ? 210 TYR B CG    1 
ATOM   5690  C CD1   . TYR B 1 210 ? -14.596 -3.801  -63.166  1.00 37.23  ? 210 TYR B CD1   1 
ATOM   5691  C CD2   . TYR B 1 210 ? -12.534 -4.881  -62.678  1.00 38.15  ? 210 TYR B CD2   1 
ATOM   5692  C CE1   . TYR B 1 210 ? -15.218 -5.027  -63.325  1.00 37.78  ? 210 TYR B CE1   1 
ATOM   5693  C CE2   . TYR B 1 210 ? -13.142 -6.120  -62.843  1.00 41.44  ? 210 TYR B CE2   1 
ATOM   5694  C CZ    . TYR B 1 210 ? -14.485 -6.187  -63.183  1.00 42.72  ? 210 TYR B CZ    1 
ATOM   5695  O OH    . TYR B 1 210 ? -15.142 -7.374  -63.367  1.00 48.44  ? 210 TYR B OH    1 
ATOM   5696  N N     . GLY B 1 211 ? -14.315 -2.871  -59.744  1.00 43.99  ? 211 GLY B N     1 
ATOM   5697  C CA    . GLY B 1 211 ? -14.343 -3.766  -58.587  1.00 43.87  ? 211 GLY B CA    1 
ATOM   5698  C C     . GLY B 1 211 ? -14.540 -3.019  -57.271  1.00 41.03  ? 211 GLY B C     1 
ATOM   5699  O O     . GLY B 1 211 ? -14.909 -1.853  -57.253  1.00 44.64  ? 211 GLY B O     1 
ATOM   5700  N N     . PRO B 1 212 ? -14.310 -3.676  -56.121  1.00 45.68  ? 212 PRO B N     1 
ATOM   5701  C CA    . PRO B 1 212 ? -14.611 -3.083  -54.822  1.00 41.88  ? 212 PRO B CA    1 
ATOM   5702  C C     . PRO B 1 212 ? -14.017 -1.695  -54.635  1.00 38.66  ? 212 PRO B C     1 
ATOM   5703  O O     . PRO B 1 212 ? -12.822 -1.514  -54.772  1.00 41.47  ? 212 PRO B O     1 
ATOM   5704  C CB    . PRO B 1 212 ? -13.980 -4.068  -53.828  1.00 49.52  ? 212 PRO B CB    1 
ATOM   5705  C CG    . PRO B 1 212 ? -13.919 -5.393  -54.546  1.00 50.91  ? 212 PRO B CG    1 
ATOM   5706  C CD    . PRO B 1 212 ? -13.780 -5.045  -56.015  1.00 51.13  ? 212 PRO B CD    1 
ATOM   5707  N N     . TYR B 1 213 ? -14.848 -0.710  -54.312  1.00 42.41  ? 213 TYR B N     1 
ATOM   5708  C CA    . TYR B 1 213 ? -14.343 0.621   -53.991  1.00 45.21  ? 213 TYR B CA    1 
ATOM   5709  C C     . TYR B 1 213 ? -13.789 0.553   -52.564  1.00 43.63  ? 213 TYR B C     1 
ATOM   5710  O O     . TYR B 1 213 ? -14.554 0.305   -51.636  1.00 32.84  ? 213 TYR B O     1 
ATOM   5711  C CB    . TYR B 1 213 ? -15.453 1.649   -54.221  1.00 42.83  ? 213 TYR B CB    1 
ATOM   5712  C CG    . TYR B 1 213 ? -15.073 3.097   -54.038  1.00 49.70  ? 213 TYR B CG    1 
ATOM   5713  C CD1   . TYR B 1 213 ? -13.837 3.567   -54.433  1.00 48.94  ? 213 TYR B CD1   1 
ATOM   5714  C CD2   . TYR B 1 213 ? -15.976 4.028   -53.533  1.00 54.79  ? 213 TYR B CD2   1 
ATOM   5715  C CE1   . TYR B 1 213 ? -13.476 4.889   -54.255  1.00 52.56  ? 213 TYR B CE1   1 
ATOM   5716  C CE2   . TYR B 1 213 ? -15.632 5.361   -53.361  1.00 57.13  ? 213 TYR B CE2   1 
ATOM   5717  C CZ    . TYR B 1 213 ? -14.370 5.795   -53.721  1.00 54.85  ? 213 TYR B CZ    1 
ATOM   5718  O OH    . TYR B 1 213 ? -13.950 7.102   -53.613  1.00 67.24  ? 213 TYR B OH    1 
ATOM   5719  N N     . VAL B 1 214 ? -12.453 0.707   -52.427  1.00 38.78  ? 214 VAL B N     1 
ATOM   5720  C CA    . VAL B 1 214 ? -11.761 0.424   -51.187  1.00 40.58  ? 214 VAL B CA    1 
ATOM   5721  C C     . VAL B 1 214 ? -11.011 1.630   -50.624  1.00 44.59  ? 214 VAL B C     1 
ATOM   5722  O O     . VAL B 1 214 ? -10.483 1.536   -49.509  1.00 49.03  ? 214 VAL B O     1 
ATOM   5723  C CB    . VAL B 1 214 ? -10.799 -0.756  -51.350  1.00 42.59  ? 214 VAL B CB    1 
ATOM   5724  C CG1   . VAL B 1 214 ? -11.575 -2.031  -51.582  1.00 41.71  ? 214 VAL B CG1   1 
ATOM   5725  C CG2   . VAL B 1 214 ? -9.785  -0.505  -52.453  1.00 46.48  ? 214 VAL B CG2   1 
ATOM   5726  N N     . ASP B 1 215 ? -10.990 2.760   -51.342  1.00 42.60  ? 215 ASP B N     1 
ATOM   5727  C CA    . ASP B 1 215 ? -10.260 3.939   -50.887  1.00 43.17  ? 215 ASP B CA    1 
ATOM   5728  C C     . ASP B 1 215 ? -10.672 4.365   -49.476  1.00 40.61  ? 215 ASP B C     1 
ATOM   5729  O O     . ASP B 1 215 ? -9.841  4.776   -48.678  1.00 41.58  ? 215 ASP B O     1 
ATOM   5730  C CB    . ASP B 1 215 ? -10.426 5.080   -51.879  1.00 45.22  ? 215 ASP B CB    1 
ATOM   5731  C CG    . ASP B 1 215 ? -9.730  4.814   -53.206  1.00 48.13  ? 215 ASP B CG    1 
ATOM   5732  O OD1   . ASP B 1 215 ? -10.100 3.832   -53.887  1.00 50.73  ? 215 ASP B OD1   1 
ATOM   5733  O OD2   . ASP B 1 215 ? -8.826  5.604   -53.561  1.00 49.32  ? 215 ASP B OD2   1 
ATOM   5734  N N     . GLY B 1 216 ? -11.953 4.211   -49.152  1.00 39.97  ? 216 GLY B N     1 
ATOM   5735  C CA    . GLY B 1 216 ? -12.479 4.610   -47.858  1.00 40.76  ? 216 GLY B CA    1 
ATOM   5736  C C     . GLY B 1 216 ? -11.947 3.786   -46.677  1.00 42.53  ? 216 GLY B C     1 
ATOM   5737  O O     . GLY B 1 216 ? -11.971 4.272   -45.536  1.00 39.31  ? 216 GLY B O     1 
ATOM   5738  N N     . ILE B 1 217 ? -11.438 2.564   -46.919  1.00 39.42  ? 217 ILE B N     1 
ATOM   5739  C CA    . ILE B 1 217 ? -11.082 1.720   -45.787  1.00 42.49  ? 217 ILE B CA    1 
ATOM   5740  C C     . ILE B 1 217 ? -9.762  2.204   -45.192  1.00 42.19  ? 217 ILE B C     1 
ATOM   5741  O O     . ILE B 1 217 ? -9.386  1.742   -44.121  1.00 42.30  ? 217 ILE B O     1 
ATOM   5742  C CB    . ILE B 1 217 ? -11.043 0.206   -46.108  1.00 42.73  ? 217 ILE B CB    1 
ATOM   5743  C CG1   . ILE B 1 217 ? -9.754  -0.227  -46.819  1.00 46.75  ? 217 ILE B CG1   1 
ATOM   5744  C CG2   . ILE B 1 217 ? -12.292 -0.228  -46.856  1.00 41.27  ? 217 ILE B CG2   1 
ATOM   5745  C CD1   . ILE B 1 217 ? -9.621  -1.722  -46.975  1.00 42.40  ? 217 ILE B CD1   1 
ATOM   5746  N N     . PHE B 1 218 ? -9.058  3.101   -45.891  1.00 39.62  ? 218 PHE B N     1 
ATOM   5747  C CA    . PHE B 1 218 ? -7.816  3.645   -45.378  1.00 38.38  ? 218 PHE B CA    1 
ATOM   5748  C C     . PHE B 1 218 ? -8.023  5.043   -44.800  1.00 40.74  ? 218 PHE B C     1 
ATOM   5749  O O     . PHE B 1 218 ? -7.043  5.756   -44.556  1.00 39.86  ? 218 PHE B O     1 
ATOM   5750  C CB    . PHE B 1 218 ? -6.784  3.678   -46.500  1.00 40.39  ? 218 PHE B CB    1 
ATOM   5751  C CG    . PHE B 1 218 ? -6.514  2.332   -47.106  1.00 38.10  ? 218 PHE B CG    1 
ATOM   5752  C CD1   . PHE B 1 218 ? -5.820  1.374   -46.395  1.00 42.26  ? 218 PHE B CD1   1 
ATOM   5753  C CD2   . PHE B 1 218 ? -6.969  2.023   -48.381  1.00 39.97  ? 218 PHE B CD2   1 
ATOM   5754  C CE1   . PHE B 1 218 ? -5.602  0.112   -46.938  1.00 45.77  ? 218 PHE B CE1   1 
ATOM   5755  C CE2   . PHE B 1 218 ? -6.729  0.776   -48.934  1.00 40.26  ? 218 PHE B CE2   1 
ATOM   5756  C CZ    . PHE B 1 218 ? -6.048  -0.179  -48.211  1.00 42.88  ? 218 PHE B CZ    1 
ATOM   5757  N N     . SER B 1 219 ? -9.291  5.452   -44.634  1.00 38.64  ? 219 SER B N     1 
ATOM   5758  C CA    . SER B 1 219 ? -9.615  6.655   -43.878  1.00 38.72  ? 219 SER B CA    1 
ATOM   5759  C C     . SER B 1 219 ? -10.055 6.267   -42.451  1.00 34.66  ? 219 SER B C     1 
ATOM   5760  O O     . SER B 1 219 ? -10.677 5.242   -42.251  1.00 38.43  ? 219 SER B O     1 
ATOM   5761  C CB    . SER B 1 219 ? -10.639 7.516   -44.627  1.00 40.79  ? 219 SER B CB    1 
ATOM   5762  O OG    . SER B 1 219 ? -11.904 6.879   -44.766  1.00 39.14  ? 219 SER B OG    1 
ATOM   5763  N N     . GLN B 1 220 ? -9.767  7.118   -41.457  1.00 34.36  ? 220 GLN B N     1 
ATOM   5764  C CA    . GLN B 1 220 ? -9.973  6.859   -40.035  1.00 32.74  ? 220 GLN B CA    1 
ATOM   5765  C C     . GLN B 1 220 ? -9.672  5.400   -39.711  1.00 38.70  ? 220 GLN B C     1 
ATOM   5766  O O     . GLN B 1 220 ? -10.570 4.661   -39.251  1.00 36.87  ? 220 GLN B O     1 
ATOM   5767  C CB    . GLN B 1 220 ? -11.377 7.295   -39.607  1.00 34.04  ? 220 GLN B CB    1 
ATOM   5768  C CG    . GLN B 1 220 ? -11.529 8.812   -39.496  1.00 39.12  ? 220 GLN B CG    1 
ATOM   5769  C CD    . GLN B 1 220 ? -12.863 9.277   -38.951  1.00 42.68  ? 220 GLN B CD    1 
ATOM   5770  O OE1   . GLN B 1 220 ? -13.783 8.493   -38.729  1.00 44.25  ? 220 GLN B OE1   1 
ATOM   5771  N NE2   . GLN B 1 220 ? -13.003 10.589  -38.799  1.00 46.77  ? 220 GLN B NE2   1 
ATOM   5772  N N     . SER B 1 221 ? -8.405  5.002   -39.938  1.00 37.91  ? 221 SER B N     1 
ATOM   5773  C CA    . SER B 1 221 ? -8.105  3.591   -40.109  1.00 44.58  ? 221 SER B CA    1 
ATOM   5774  C C     . SER B 1 221 ? -6.634  3.263   -39.838  1.00 43.43  ? 221 SER B C     1 
ATOM   5775  O O     . SER B 1 221 ? -5.778  4.129   -39.928  1.00 35.49  ? 221 SER B O     1 
ATOM   5776  C CB    . SER B 1 221 ? -8.517  3.204   -41.516  1.00 53.05  ? 221 SER B CB    1 
ATOM   5777  O OG    . SER B 1 221 ? -8.065  1.900   -41.848  1.00 62.39  ? 221 SER B OG    1 
ATOM   5778  N N     . ASN B 1 222 ? -6.356  1.987   -39.536  1.00 42.11  ? 222 ASN B N     1 
ATOM   5779  C CA    . ASN B 1 222 ? -5.007  1.496   -39.313  1.00 40.80  ? 222 ASN B CA    1 
ATOM   5780  C C     . ASN B 1 222 ? -4.702  0.309   -40.225  1.00 41.27  ? 222 ASN B C     1 
ATOM   5781  O O     . ASN B 1 222 ? -4.054  -0.637  -39.789  1.00 41.08  ? 222 ASN B O     1 
ATOM   5782  C CB    . ASN B 1 222 ? -4.815  1.094   -37.846  1.00 43.09  ? 222 ASN B CB    1 
ATOM   5783  C CG    . ASN B 1 222 ? -5.868  0.156   -37.275  1.00 48.53  ? 222 ASN B CG    1 
ATOM   5784  O OD1   . ASN B 1 222 ? -6.698  -0.401  -37.987  1.00 60.54  ? 222 ASN B OD1   1 
ATOM   5785  N ND2   . ASN B 1 222 ? -5.864  -0.021  -35.964  1.00 51.34  ? 222 ASN B ND2   1 
ATOM   5786  N N     . PHE B 1 223 ? -5.221  0.344   -41.460  1.00 43.82  ? 223 PHE B N     1 
ATOM   5787  C CA    . PHE B 1 223 ? -5.191  -0.778  -42.388  1.00 39.10  ? 223 PHE B CA    1 
ATOM   5788  C C     . PHE B 1 223 ? -4.096  -0.574  -43.425  1.00 41.39  ? 223 PHE B C     1 
ATOM   5789  O O     . PHE B 1 223 ? -3.871  -1.452  -44.261  1.00 42.35  ? 223 PHE B O     1 
ATOM   5790  C CB    . PHE B 1 223 ? -6.470  -0.909  -43.220  1.00 37.45  ? 223 PHE B CB    1 
ATOM   5791  C CG    . PHE B 1 223 ? -7.733  -1.292  -42.513  1.00 39.79  ? 223 PHE B CG    1 
ATOM   5792  C CD1   . PHE B 1 223 ? -7.729  -1.818  -41.228  1.00 48.18  ? 223 PHE B CD1   1 
ATOM   5793  C CD2   . PHE B 1 223 ? -8.953  -1.095  -43.133  1.00 46.70  ? 223 PHE B CD2   1 
ATOM   5794  C CE1   . PHE B 1 223 ? -8.917  -2.148  -40.585  1.00 44.12  ? 223 PHE B CE1   1 
ATOM   5795  C CE2   . PHE B 1 223 ? -10.140 -1.391  -42.471  1.00 52.88  ? 223 PHE B CE2   1 
ATOM   5796  C CZ    . PHE B 1 223 ? -10.121 -1.926  -41.200  1.00 42.95  ? 223 PHE B CZ    1 
ATOM   5797  N N     . GLY B 1 224 ? -3.450  0.595   -43.393  1.00 41.90  ? 224 GLY B N     1 
ATOM   5798  C CA    . GLY B 1 224 ? -2.442  0.914   -44.386  1.00 41.33  ? 224 GLY B CA    1 
ATOM   5799  C C     . GLY B 1 224 ? -1.892  2.322   -44.233  1.00 44.93  ? 224 GLY B C     1 
ATOM   5800  O O     . GLY B 1 224 ? -2.491  3.179   -43.587  1.00 50.20  ? 224 GLY B O     1 
ATOM   5801  N N     . VAL B 1 225 ? -0.734  2.545   -44.856  1.00 49.02  ? 225 VAL B N     1 
ATOM   5802  C CA    . VAL B 1 225 ? -0.088  3.844   -44.821  1.00 47.06  ? 225 VAL B CA    1 
ATOM   5803  C C     . VAL B 1 225 ? -0.221  4.484   -46.191  1.00 47.16  ? 225 VAL B C     1 
ATOM   5804  O O     . VAL B 1 225 ? 0.300   3.977   -47.181  1.00 46.93  ? 225 VAL B O     1 
ATOM   5805  C CB    . VAL B 1 225 ? 1.396   3.728   -44.443  1.00 46.61  ? 225 VAL B CB    1 
ATOM   5806  C CG1   . VAL B 1 225 ? 1.989   5.097   -44.189  1.00 45.65  ? 225 VAL B CG1   1 
ATOM   5807  C CG2   . VAL B 1 225 ? 1.603   2.800   -43.260  1.00 49.78  ? 225 VAL B CG2   1 
ATOM   5808  N N     . VAL B 1 226 ? -0.864  5.643   -46.232  1.00 46.51  ? 226 VAL B N     1 
ATOM   5809  C CA    . VAL B 1 226 ? -1.050  6.310   -47.499  1.00 43.48  ? 226 VAL B CA    1 
ATOM   5810  C C     . VAL B 1 226 ? 0.198   7.130   -47.852  1.00 48.48  ? 226 VAL B C     1 
ATOM   5811  O O     . VAL B 1 226 ? 0.652   7.996   -47.100  1.00 47.13  ? 226 VAL B O     1 
ATOM   5812  C CB    . VAL B 1 226 ? -2.329  7.137   -47.417  1.00 38.11  ? 226 VAL B CB    1 
ATOM   5813  C CG1   . VAL B 1 226 ? -2.617  7.869   -48.711  1.00 42.71  ? 226 VAL B CG1   1 
ATOM   5814  C CG2   . VAL B 1 226 ? -3.483  6.239   -47.029  1.00 41.63  ? 226 VAL B CG2   1 
ATOM   5815  N N     . THR B 1 227 ? 0.735   6.865   -49.042  1.00 51.17  ? 227 THR B N     1 
ATOM   5816  C CA    . THR B 1 227 ? 1.959   7.515   -49.483  1.00 51.73  ? 227 THR B CA    1 
ATOM   5817  C C     . THR B 1 227 ? 1.720   8.459   -50.656  1.00 51.10  ? 227 THR B C     1 
ATOM   5818  O O     . THR B 1 227 ? 2.607   9.234   -50.966  1.00 47.34  ? 227 THR B O     1 
ATOM   5819  C CB    . THR B 1 227 ? 3.004   6.467   -49.852  1.00 48.65  ? 227 THR B CB    1 
ATOM   5820  O OG1   . THR B 1 227 ? 2.357   5.525   -50.714  1.00 50.04  ? 227 THR B OG1   1 
ATOM   5821  C CG2   . THR B 1 227 ? 3.547   5.765   -48.626  1.00 52.33  ? 227 THR B CG2   1 
ATOM   5822  N N     . LYS B 1 228 ? 0.553   8.378   -51.314  1.00 53.87  ? 228 LYS B N     1 
ATOM   5823  C CA    . LYS B 1 228 ? 0.137   9.380   -52.294  1.00 49.20  ? 228 LYS B CA    1 
ATOM   5824  C C     . LYS B 1 228 ? -1.388  9.401   -52.356  1.00 50.77  ? 228 LYS B C     1 
ATOM   5825  O O     . LYS B 1 228 ? -2.070  8.375   -52.120  1.00 44.59  ? 228 LYS B O     1 
ATOM   5826  C CB    . LYS B 1 228 ? 0.635   9.074   -53.717  1.00 52.84  ? 228 LYS B CB    1 
ATOM   5827  C CG    . LYS B 1 228 ? 2.091   8.651   -53.848  1.00 59.53  ? 228 LYS B CG    1 
ATOM   5828  C CD    . LYS B 1 228 ? 2.457   8.089   -55.205  1.00 64.84  ? 228 LYS B CD    1 
ATOM   5829  C CE    . LYS B 1 228 ? 3.952   8.082   -55.458  1.00 59.02  ? 228 LYS B CE    1 
ATOM   5830  N NZ    . LYS B 1 228 ? 4.701   7.558   -54.291  1.00 62.75  ? 228 LYS B NZ    1 
ATOM   5831  N N     . MET B 1 229 ? -1.915  10.575  -52.717  1.00 44.41  ? 229 MET B N     1 
ATOM   5832  C CA    . MET B 1 229 ? -3.352  10.735  -52.748  1.00 42.16  ? 229 MET B CA    1 
ATOM   5833  C C     . MET B 1 229 ? -3.658  11.886  -53.673  1.00 41.46  ? 229 MET B C     1 
ATOM   5834  O O     . MET B 1 229 ? -3.015  12.920  -53.591  1.00 41.71  ? 229 MET B O     1 
ATOM   5835  C CB    . MET B 1 229 ? -3.927  11.040  -51.364  1.00 46.67  ? 229 MET B CB    1 
ATOM   5836  C CG    . MET B 1 229 ? -5.431  11.142  -51.328  1.00 45.59  ? 229 MET B CG    1 
ATOM   5837  S SD    . MET B 1 229 ? -6.031  11.859  -49.783  1.00 45.24  ? 229 MET B SD    1 
ATOM   5838  C CE    . MET B 1 229 ? -6.147  13.587  -50.239  1.00 41.32  ? 229 MET B CE    1 
ATOM   5839  N N     . GLY B 1 230 ? -4.600  11.632  -54.585  1.00 47.37  ? 230 GLY B N     1 
ATOM   5840  C CA    . GLY B 1 230 ? -5.084  12.642  -55.498  1.00 47.55  ? 230 GLY B CA    1 
ATOM   5841  C C     . GLY B 1 230 ? -6.267  13.336  -54.863  1.00 46.28  ? 230 GLY B C     1 
ATOM   5842  O O     . GLY B 1 230 ? -6.951  12.698  -54.077  1.00 46.06  ? 230 GLY B O     1 
ATOM   5843  N N     . ILE B 1 231 ? -6.428  14.635  -55.146  1.00 46.47  ? 231 ILE B N     1 
ATOM   5844  C CA    . ILE B 1 231 ? -7.596  15.371  -54.719  1.00 44.54  ? 231 ILE B CA    1 
ATOM   5845  C C     . ILE B 1 231 ? -8.037  16.258  -55.868  1.00 43.45  ? 231 ILE B C     1 
ATOM   5846  O O     . ILE B 1 231 ? -7.201  16.749  -56.616  1.00 44.15  ? 231 ILE B O     1 
ATOM   5847  C CB    . ILE B 1 231 ? -7.347  16.184  -53.433  1.00 48.74  ? 231 ILE B CB    1 
ATOM   5848  C CG1   . ILE B 1 231 ? -8.671  16.554  -52.758  1.00 46.38  ? 231 ILE B CG1   1 
ATOM   5849  C CG2   . ILE B 1 231 ? -6.497  17.410  -53.711  1.00 51.26  ? 231 ILE B CG2   1 
ATOM   5850  C CD1   . ILE B 1 231 ? -8.518  17.261  -51.427  1.00 49.48  ? 231 ILE B CD1   1 
ATOM   5851  N N     . TRP B 1 232 ? -9.364  16.398  -55.984  1.00 43.86  ? 232 TRP B N     1 
ATOM   5852  C CA    . TRP B 1 232 ? -10.006 17.326  -56.881  1.00 42.81  ? 232 TRP B CA    1 
ATOM   5853  C C     . TRP B 1 232 ? -9.929  18.733  -56.292  1.00 46.53  ? 232 TRP B C     1 
ATOM   5854  O O     . TRP B 1 232 ? -10.117 18.914  -55.083  1.00 44.63  ? 232 TRP B O     1 
ATOM   5855  C CB    . TRP B 1 232 ? -11.453 16.883  -57.151  1.00 41.14  ? 232 TRP B CB    1 
ATOM   5856  C CG    . TRP B 1 232 ? -11.562 15.600  -57.911  1.00 44.59  ? 232 TRP B CG    1 
ATOM   5857  C CD1   . TRP B 1 232 ? -10.587 14.994  -58.652  1.00 44.84  ? 232 TRP B CD1   1 
ATOM   5858  C CD2   . TRP B 1 232 ? -12.692 14.706  -57.951  1.00 47.78  ? 232 TRP B CD2   1 
ATOM   5859  N NE1   . TRP B 1 232 ? -11.030 13.797  -59.156  1.00 48.49  ? 232 TRP B NE1   1 
ATOM   5860  C CE2   . TRP B 1 232 ? -12.313 13.586  -58.729  1.00 44.20  ? 232 TRP B CE2   1 
ATOM   5861  C CE3   . TRP B 1 232 ? -13.952 14.706  -57.348  1.00 49.89  ? 232 TRP B CE3   1 
ATOM   5862  C CZ2   . TRP B 1 232 ? -13.171 12.522  -58.976  1.00 41.96  ? 232 TRP B CZ2   1 
ATOM   5863  C CZ3   . TRP B 1 232 ? -14.792 13.639  -57.570  1.00 48.31  ? 232 TRP B CZ3   1 
ATOM   5864  C CH2   . TRP B 1 232 ? -14.418 12.578  -58.396  1.00 45.26  ? 232 TRP B CH2   1 
ATOM   5865  N N     . LEU B 1 233 ? -9.650  19.699  -57.184  1.00 42.31  ? 233 LEU B N     1 
ATOM   5866  C CA    . LEU B 1 233 ? -9.565  21.123  -56.877  1.00 46.29  ? 233 LEU B CA    1 
ATOM   5867  C C     . LEU B 1 233 ? -10.591 21.871  -57.720  1.00 44.28  ? 233 LEU B C     1 
ATOM   5868  O O     . LEU B 1 233 ? -10.749 21.553  -58.897  1.00 41.28  ? 233 LEU B O     1 
ATOM   5869  C CB    . LEU B 1 233 ? -8.161  21.638  -57.241  1.00 48.17  ? 233 LEU B CB    1 
ATOM   5870  C CG    . LEU B 1 233 ? -6.991  20.926  -56.567  1.00 49.74  ? 233 LEU B CG    1 
ATOM   5871  C CD1   . LEU B 1 233 ? -5.671  21.327  -57.200  1.00 47.47  ? 233 LEU B CD1   1 
ATOM   5872  C CD2   . LEU B 1 233 ? -6.978  21.239  -55.074  1.00 50.14  ? 233 LEU B CD2   1 
ATOM   5873  N N     . MET B 1 234 ? -11.198 22.920  -57.152  1.00 41.75  ? 234 MET B N     1 
ATOM   5874  C CA    . MET B 1 234 ? -12.235 23.664  -57.853  1.00 45.98  ? 234 MET B CA    1 
ATOM   5875  C C     . MET B 1 234 ? -11.614 24.661  -58.828  1.00 47.68  ? 234 MET B C     1 
ATOM   5876  O O     . MET B 1 234 ? -10.703 25.379  -58.431  1.00 60.75  ? 234 MET B O     1 
ATOM   5877  C CB    . MET B 1 234 ? -13.080 24.431  -56.838  1.00 46.39  ? 234 MET B CB    1 
ATOM   5878  C CG    . MET B 1 234 ? -14.078 25.356  -57.452  1.00 49.15  ? 234 MET B CG    1 
ATOM   5879  S SD    . MET B 1 234 ? -15.263 26.009  -56.262  1.00 50.30  ? 234 MET B SD    1 
ATOM   5880  C CE    . MET B 1 234 ? -14.160 26.874  -55.154  1.00 59.87  ? 234 MET B CE    1 
ATOM   5881  N N     . PRO B 1 235 ? -12.074 24.789  -60.103  1.00 50.76  ? 235 PRO B N     1 
ATOM   5882  C CA    . PRO B 1 235 ? -11.627 25.871  -60.989  1.00 49.55  ? 235 PRO B CA    1 
ATOM   5883  C C     . PRO B 1 235 ? -11.975 27.217  -60.387  1.00 45.89  ? 235 PRO B C     1 
ATOM   5884  O O     . PRO B 1 235 ? -13.077 27.351  -59.873  1.00 51.58  ? 235 PRO B O     1 
ATOM   5885  C CB    . PRO B 1 235 ? -12.463 25.746  -62.268  1.00 45.82  ? 235 PRO B CB    1 
ATOM   5886  C CG    . PRO B 1 235 ? -12.929 24.311  -62.246  1.00 49.81  ? 235 PRO B CG    1 
ATOM   5887  C CD    . PRO B 1 235 ? -13.060 23.938  -60.775  1.00 51.78  ? 235 PRO B CD    1 
ATOM   5888  N N     . GLU B 1 236 ? -11.050 28.182  -60.475  1.00 46.63  ? 236 GLU B N     1 
ATOM   5889  C CA    . GLU B 1 236 ? -11.317 29.562  -60.072  1.00 51.74  ? 236 GLU B CA    1 
ATOM   5890  C C     . GLU B 1 236 ? -12.686 29.929  -60.597  1.00 43.06  ? 236 GLU B C     1 
ATOM   5891  O O     . GLU B 1 236 ? -12.924 29.743  -61.763  1.00 52.71  ? 236 GLU B O     1 
ATOM   5892  C CB    . GLU B 1 236 ? -10.249 30.494  -60.646  1.00 63.08  ? 236 GLU B CB    1 
ATOM   5893  C CG    . GLU B 1 236 ? -10.271 31.933  -60.146  1.00 64.81  ? 236 GLU B CG    1 
ATOM   5894  C CD    . GLU B 1 236 ? -8.963  32.681  -60.390  1.00 66.71  ? 236 GLU B CD    1 
ATOM   5895  O OE1   . GLU B 1 236 ? -8.500  32.726  -61.548  1.00 66.37  ? 236 GLU B OE1   1 
ATOM   5896  O OE2   . GLU B 1 236 ? -8.380  33.187  -59.415  1.00 78.50  ? 236 GLU B OE2   1 
ATOM   5897  N N     . PRO B 1 237 ? -13.675 30.282  -59.766  1.00 50.51  ? 237 PRO B N     1 
ATOM   5898  C CA    . PRO B 1 237 ? -14.977 30.703  -60.273  1.00 51.17  ? 237 PRO B CA    1 
ATOM   5899  C C     . PRO B 1 237 ? -14.944 32.126  -60.812  1.00 54.99  ? 237 PRO B C     1 
ATOM   5900  O O     . PRO B 1 237 ? -13.944 32.821  -60.682  1.00 51.37  ? 237 PRO B O     1 
ATOM   5901  C CB    . PRO B 1 237 ? -15.892 30.644  -59.040  1.00 52.17  ? 237 PRO B CB    1 
ATOM   5902  C CG    . PRO B 1 237 ? -14.953 30.853  -57.886  1.00 51.86  ? 237 PRO B CG    1 
ATOM   5903  C CD    . PRO B 1 237 ? -13.638 30.223  -58.302  1.00 50.58  ? 237 PRO B CD    1 
ATOM   5904  N N     . ALA B 1 238 ? -16.079 32.569  -61.353  1.00 59.52  ? 238 ALA B N     1 
ATOM   5905  C CA    . ALA B 1 238 ? -16.123 33.828  -62.075  1.00 65.04  ? 238 ALA B CA    1 
ATOM   5906  C C     . ALA B 1 238 ? -16.481 34.980  -61.140  1.00 61.01  ? 238 ALA B C     1 
ATOM   5907  O O     . ALA B 1 238 ? -16.590 36.119  -61.576  1.00 70.38  ? 238 ALA B O     1 
ATOM   5908  C CB    . ALA B 1 238 ? -17.107 33.704  -63.221  1.00 62.11  ? 238 ALA B CB    1 
ATOM   5909  N N     . GLY B 1 239 ? -16.687 34.684  -59.858  1.00 62.30  ? 239 GLY B N     1 
ATOM   5910  C CA    . GLY B 1 239 ? -17.186 35.665  -58.903  1.00 62.07  ? 239 GLY B CA    1 
ATOM   5911  C C     . GLY B 1 239 ? -17.266 35.053  -57.509  1.00 62.37  ? 239 GLY B C     1 
ATOM   5912  O O     . GLY B 1 239 ? -17.393 33.842  -57.390  1.00 67.04  ? 239 GLY B O     1 
ATOM   5913  N N     . TYR B 1 240 ? -17.171 35.890  -56.473  1.00 64.40  ? 240 TYR B N     1 
ATOM   5914  C CA    . TYR B 1 240 ? -17.183 35.459  -55.081  1.00 55.96  ? 240 TYR B CA    1 
ATOM   5915  C C     . TYR B 1 240 ? -17.788 36.595  -54.263  1.00 56.63  ? 240 TYR B C     1 
ATOM   5916  O O     . TYR B 1 240 ? -17.300 37.705  -54.355  1.00 58.51  ? 240 TYR B O     1 
ATOM   5917  C CB    . TYR B 1 240 ? -15.754 35.089  -54.663  1.00 54.76  ? 240 TYR B CB    1 
ATOM   5918  C CG    . TYR B 1 240 ? -15.512 34.774  -53.203  1.00 60.16  ? 240 TYR B CG    1 
ATOM   5919  C CD1   . TYR B 1 240 ? -16.112 33.678  -52.600  1.00 58.21  ? 240 TYR B CD1   1 
ATOM   5920  C CD2   . TYR B 1 240 ? -14.658 35.543  -52.422  1.00 62.93  ? 240 TYR B CD2   1 
ATOM   5921  C CE1   . TYR B 1 240 ? -15.885 33.357  -51.273  1.00 54.13  ? 240 TYR B CE1   1 
ATOM   5922  C CE2   . TYR B 1 240 ? -14.440 35.252  -51.081  1.00 62.40  ? 240 TYR B CE2   1 
ATOM   5923  C CZ    . TYR B 1 240 ? -15.060 34.155  -50.497  1.00 61.42  ? 240 TYR B CZ    1 
ATOM   5924  O OH    . TYR B 1 240 ? -14.861 33.805  -49.171  1.00 50.66  ? 240 TYR B OH    1 
ATOM   5925  N N     . ARG B 1 241 ? -18.888 36.340  -53.537  1.00 62.70  ? 241 ARG B N     1 
ATOM   5926  C CA    . ARG B 1 241 ? -19.505 37.305  -52.632  1.00 61.33  ? 241 ARG B CA    1 
ATOM   5927  C C     . ARG B 1 241 ? -19.665 36.678  -51.232  1.00 57.29  ? 241 ARG B C     1 
ATOM   5928  O O     . ARG B 1 241 ? -20.609 35.931  -50.945  1.00 49.59  ? 241 ARG B O     1 
ATOM   5929  C CB    . ARG B 1 241 ? -20.854 37.778  -53.202  1.00 69.95  ? 241 ARG B CB    1 
ATOM   5930  C CG    . ARG B 1 241 ? -20.783 38.698  -54.419  1.00 83.84  ? 241 ARG B CG    1 
ATOM   5931  C CD    . ARG B 1 241 ? -20.399 40.131  -54.075  1.00 108.19 ? 241 ARG B CD    1 
ATOM   5932  N NE    . ARG B 1 241 ? -21.481 40.928  -53.485  1.00 119.25 ? 241 ARG B NE    1 
ATOM   5933  C CZ    . ARG B 1 241 ? -21.318 42.072  -52.811  1.00 103.17 ? 241 ARG B CZ    1 
ATOM   5934  N NH1   . ARG B 1 241 ? -20.110 42.495  -52.479  1.00 93.60  ? 241 ARG B NH1   1 
ATOM   5935  N NH2   . ARG B 1 241 ? -22.375 42.775  -52.432  1.00 97.76  ? 241 ARG B NH2   1 
ATOM   5936  N N     . PRO B 1 242 ? -18.741 36.914  -50.281  1.00 52.91  ? 242 PRO B N     1 
ATOM   5937  C CA    . PRO B 1 242 ? -18.945 36.457  -48.904  1.00 52.22  ? 242 PRO B CA    1 
ATOM   5938  C C     . PRO B 1 242 ? -19.893 37.370  -48.138  1.00 52.34  ? 242 PRO B C     1 
ATOM   5939  O O     . PRO B 1 242 ? -20.005 38.548  -48.448  1.00 55.28  ? 242 PRO B O     1 
ATOM   5940  C CB    . PRO B 1 242 ? -17.536 36.490  -48.322  1.00 51.35  ? 242 PRO B CB    1 
ATOM   5941  C CG    . PRO B 1 242 ? -16.902 37.632  -49.060  1.00 55.32  ? 242 PRO B CG    1 
ATOM   5942  C CD    . PRO B 1 242 ? -17.421 37.513  -50.479  1.00 56.41  ? 242 PRO B CD    1 
ATOM   5943  N N     . TYR B 1 243 ? -20.601 36.800  -47.160  1.00 48.48  ? 243 TYR B N     1 
ATOM   5944  C CA    . TYR B 1 243 ? -21.593 37.548  -46.419  1.00 44.84  ? 243 TYR B CA    1 
ATOM   5945  C C     . TYR B 1 243 ? -21.708 37.037  -44.990  1.00 39.20  ? 243 TYR B C     1 
ATOM   5946  O O     . TYR B 1 243 ? -21.235 35.958  -44.688  1.00 40.88  ? 243 TYR B O     1 
ATOM   5947  C CB    . TYR B 1 243 ? -22.933 37.465  -47.131  1.00 49.18  ? 243 TYR B CB    1 
ATOM   5948  C CG    . TYR B 1 243 ? -23.519 36.084  -47.240  1.00 57.87  ? 243 TYR B CG    1 
ATOM   5949  C CD1   . TYR B 1 243 ? -24.104 35.436  -46.161  1.00 61.27  ? 243 TYR B CD1   1 
ATOM   5950  C CD2   . TYR B 1 243 ? -23.504 35.425  -48.456  1.00 61.73  ? 243 TYR B CD2   1 
ATOM   5951  C CE1   . TYR B 1 243 ? -24.660 34.171  -46.304  1.00 68.66  ? 243 TYR B CE1   1 
ATOM   5952  C CE2   . TYR B 1 243 ? -24.052 34.163  -48.610  1.00 66.16  ? 243 TYR B CE2   1 
ATOM   5953  C CZ    . TYR B 1 243 ? -24.645 33.534  -47.538  1.00 65.06  ? 243 TYR B CZ    1 
ATOM   5954  O OH    . TYR B 1 243 ? -25.187 32.296  -47.790  1.00 59.87  ? 243 TYR B OH    1 
ATOM   5955  N N     . LEU B 1 244 ? -22.347 37.837  -44.133  1.00 41.50  ? 244 LEU B N     1 
ATOM   5956  C CA    . LEU B 1 244 ? -22.640 37.480  -42.758  1.00 43.78  ? 244 LEU B CA    1 
ATOM   5957  C C     . LEU B 1 244 ? -24.042 37.948  -42.413  1.00 46.63  ? 244 LEU B C     1 
ATOM   5958  O O     . LEU B 1 244 ? -24.308 39.139  -42.567  1.00 49.18  ? 244 LEU B O     1 
ATOM   5959  C CB    . LEU B 1 244 ? -21.642 38.158  -41.831  1.00 44.58  ? 244 LEU B CB    1 
ATOM   5960  C CG    . LEU B 1 244 ? -22.008 38.125  -40.348  1.00 54.13  ? 244 LEU B CG    1 
ATOM   5961  C CD1   . LEU B 1 244 ? -21.860 36.720  -39.777  1.00 53.18  ? 244 LEU B CD1   1 
ATOM   5962  C CD2   . LEU B 1 244 ? -21.144 39.095  -39.547  1.00 52.29  ? 244 LEU B CD2   1 
ATOM   5963  N N     . ILE B 1 245 ? -24.886 37.008  -41.936  1.00 46.77  ? 245 ILE B N     1 
ATOM   5964  C CA    . ILE B 1 245 ? -26.235 37.289  -41.449  1.00 46.73  ? 245 ILE B CA    1 
ATOM   5965  C C     . ILE B 1 245 ? -26.273 37.069  -39.935  1.00 43.71  ? 245 ILE B C     1 
ATOM   5966  O O     . ILE B 1 245 ? -25.983 35.970  -39.469  1.00 51.42  ? 245 ILE B O     1 
ATOM   5967  C CB    . ILE B 1 245 ? -27.277 36.379  -42.132  1.00 45.52  ? 245 ILE B CB    1 
ATOM   5968  C CG1   . ILE B 1 245 ? -27.140 36.355  -43.652  1.00 46.10  ? 245 ILE B CG1   1 
ATOM   5969  C CG2   . ILE B 1 245 ? -28.681 36.763  -41.707  1.00 46.93  ? 245 ILE B CG2   1 
ATOM   5970  C CD1   . ILE B 1 245 ? -28.276 35.662  -44.365  1.00 41.81  ? 245 ILE B CD1   1 
ATOM   5971  N N     . THR B 1 246 ? -26.674 38.088  -39.168  1.00 41.26  ? 246 THR B N     1 
ATOM   5972  C CA    . THR B 1 246 ? -26.659 37.987  -37.710  1.00 41.64  ? 246 THR B CA    1 
ATOM   5973  C C     . THR B 1 246 ? -28.081 37.920  -37.148  1.00 40.73  ? 246 THR B C     1 
ATOM   5974  O O     . THR B 1 246 ? -29.030 38.389  -37.781  1.00 37.18  ? 246 THR B O     1 
ATOM   5975  C CB    . THR B 1 246 ? -25.814 39.113  -37.091  1.00 43.33  ? 246 THR B CB    1 
ATOM   5976  O OG1   . THR B 1 246 ? -26.436 40.390  -37.244  1.00 42.08  ? 246 THR B OG1   1 
ATOM   5977  C CG2   . THR B 1 246 ? -24.438 39.181  -37.710  1.00 42.07  ? 246 THR B CG2   1 
ATOM   5978  N N     . PHE B 1 247 ? -28.210 37.319  -35.949  1.00 47.55  ? 247 PHE B N     1 
ATOM   5979  C CA    . PHE B 1 247 ? -29.490 37.173  -35.265  1.00 50.82  ? 247 PHE B CA    1 
ATOM   5980  C C     . PHE B 1 247 ? -29.339 37.541  -33.784  1.00 47.19  ? 247 PHE B C     1 
ATOM   5981  O O     . PHE B 1 247 ? -28.399 37.077  -33.138  1.00 45.81  ? 247 PHE B O     1 
ATOM   5982  C CB    . PHE B 1 247 ? -29.994 35.735  -35.452  1.00 56.74  ? 247 PHE B CB    1 
ATOM   5983  C CG    . PHE B 1 247 ? -30.095 35.251  -36.882  1.00 48.84  ? 247 PHE B CG    1 
ATOM   5984  C CD1   . PHE B 1 247 ? -31.192 35.568  -37.667  1.00 44.39  ? 247 PHE B CD1   1 
ATOM   5985  C CD2   . PHE B 1 247 ? -29.100 34.459  -37.437  1.00 49.55  ? 247 PHE B CD2   1 
ATOM   5986  C CE1   . PHE B 1 247 ? -31.280 35.116  -38.980  1.00 43.47  ? 247 PHE B CE1   1 
ATOM   5987  C CE2   . PHE B 1 247 ? -29.178 34.020  -38.753  1.00 48.21  ? 247 PHE B CE2   1 
ATOM   5988  C CZ    . PHE B 1 247 ? -30.270 34.351  -39.522  1.00 44.09  ? 247 PHE B CZ    1 
ATOM   5989  N N     . GLU B 1 248 ? -30.294 38.319  -33.245  1.00 44.05  ? 248 GLU B N     1 
ATOM   5990  C CA    . GLU B 1 248 ? -30.244 38.860  -31.891  1.00 48.88  ? 248 GLU B CA    1 
ATOM   5991  C C     . GLU B 1 248 ? -30.392 37.822  -30.775  1.00 51.88  ? 248 GLU B C     1 
ATOM   5992  O O     . GLU B 1 248 ? -29.796 37.975  -29.707  1.00 55.12  ? 248 GLU B O     1 
ATOM   5993  C CB    . GLU B 1 248 ? -31.388 39.853  -31.653  1.00 62.51  ? 248 GLU B CB    1 
ATOM   5994  C CG    . GLU B 1 248 ? -31.096 41.255  -32.157  1.00 73.50  ? 248 GLU B CG    1 
ATOM   5995  C CD    . GLU B 1 248 ? -29.797 41.872  -31.658  1.00 75.91  ? 248 GLU B CD    1 
ATOM   5996  O OE1   . GLU B 1 248 ? -29.764 42.281  -30.480  1.00 75.53  ? 248 GLU B OE1   1 
ATOM   5997  O OE2   . GLU B 1 248 ? -28.809 41.916  -32.446  1.00 69.06  ? 248 GLU B OE2   1 
ATOM   5998  N N     . ASN B 1 249 ? -31.231 36.804  -30.975  1.00 51.86  ? 249 ASN B N     1 
ATOM   5999  C CA    . ASN B 1 249 ? -31.724 35.993  -29.871  1.00 53.60  ? 249 ASN B CA    1 
ATOM   6000  C C     . ASN B 1 249 ? -31.211 34.555  -29.925  1.00 50.62  ? 249 ASN B C     1 
ATOM   6001  O O     . ASN B 1 249 ? -31.118 33.935  -30.981  1.00 53.35  ? 249 ASN B O     1 
ATOM   6002  C CB    . ASN B 1 249 ? -33.250 35.992  -29.845  1.00 57.50  ? 249 ASN B CB    1 
ATOM   6003  C CG    . ASN B 1 249 ? -33.823 37.383  -29.967  1.00 48.62  ? 249 ASN B CG    1 
ATOM   6004  O OD1   . ASN B 1 249 ? -33.932 38.105  -28.991  1.00 55.84  ? 249 ASN B OD1   1 
ATOM   6005  N ND2   . ASN B 1 249 ? -34.200 37.768  -31.162  1.00 51.59  ? 249 ASN B ND2   1 
ATOM   6006  N N     . GLU B 1 250 ? -30.909 34.006  -28.753  1.00 46.05  ? 250 GLU B N     1 
ATOM   6007  C CA    . GLU B 1 250 ? -30.396 32.650  -28.678  1.00 50.32  ? 250 GLU B CA    1 
ATOM   6008  C C     . GLU B 1 250 ? -31.400 31.673  -29.299  1.00 49.42  ? 250 GLU B C     1 
ATOM   6009  O O     . GLU B 1 250 ? -30.965 30.788  -30.005  1.00 45.68  ? 250 GLU B O     1 
ATOM   6010  C CB    . GLU B 1 250 ? -30.044 32.272  -27.235  1.00 53.04  ? 250 GLU B CB    1 
ATOM   6011  C CG    . GLU B 1 250 ? -31.223 32.338  -26.284  1.00 60.69  ? 250 GLU B CG    1 
ATOM   6012  C CD    . GLU B 1 250 ? -30.910 31.969  -24.847  1.00 63.23  ? 250 GLU B CD    1 
ATOM   6013  O OE1   . GLU B 1 250 ? -29.801 31.445  -24.580  1.00 61.22  ? 250 GLU B OE1   1 
ATOM   6014  O OE2   . GLU B 1 250 ? -31.787 32.199  -24.003  1.00 61.45  ? 250 GLU B OE2   1 
ATOM   6015  N N     . ASP B 1 251 ? -32.722 31.861  -29.090  1.00 49.10  ? 251 ASP B N     1 
ATOM   6016  C CA    . ASP B 1 251 ? -33.760 30.981  -29.618  1.00 42.22  ? 251 ASP B CA    1 
ATOM   6017  C C     . ASP B 1 251 ? -33.968 31.084  -31.123  1.00 44.15  ? 251 ASP B C     1 
ATOM   6018  O O     . ASP B 1 251 ? -34.715 30.297  -31.692  1.00 49.43  ? 251 ASP B O     1 
ATOM   6019  C CB    . ASP B 1 251 ? -35.128 31.308  -29.033  1.00 43.87  ? 251 ASP B CB    1 
ATOM   6020  C CG    . ASP B 1 251 ? -35.269 30.832  -27.607  1.00 55.14  ? 251 ASP B CG    1 
ATOM   6021  O OD1   . ASP B 1 251 ? -34.300 30.223  -27.076  1.00 53.23  ? 251 ASP B OD1   1 
ATOM   6022  O OD2   . ASP B 1 251 ? -36.360 31.052  -27.049  1.00 70.59  ? 251 ASP B OD2   1 
ATOM   6023  N N     . ASP B 1 252 ? -33.386 32.096  -31.760  1.00 43.26  ? 252 ASP B N     1 
ATOM   6024  C CA    . ASP B 1 252 ? -33.471 32.219  -33.196  1.00 41.37  ? 252 ASP B CA    1 
ATOM   6025  C C     . ASP B 1 252 ? -32.894 30.976  -33.878  1.00 47.37  ? 252 ASP B C     1 
ATOM   6026  O O     . ASP B 1 252 ? -33.180 30.740  -35.060  1.00 41.98  ? 252 ASP B O     1 
ATOM   6027  C CB    . ASP B 1 252 ? -32.764 33.489  -33.687  1.00 43.92  ? 252 ASP B CB    1 
ATOM   6028  C CG    . ASP B 1 252 ? -33.511 34.811  -33.516  1.00 51.02  ? 252 ASP B CG    1 
ATOM   6029  O OD1   . ASP B 1 252 ? -34.795 34.826  -33.404  1.00 46.48  ? 252 ASP B OD1   1 
ATOM   6030  O OD2   . ASP B 1 252 ? -32.802 35.840  -33.516  1.00 51.25  ? 252 ASP B OD2   1 
ATOM   6031  N N     . ILE B 1 253 ? -32.056 30.186  -33.180  1.00 46.68  ? 253 ILE B N     1 
ATOM   6032  C CA    . ILE B 1 253 ? -31.357 29.124  -33.888  1.00 45.84  ? 253 ILE B CA    1 
ATOM   6033  C C     . ILE B 1 253 ? -32.350 28.082  -34.415  1.00 45.73  ? 253 ILE B C     1 
ATOM   6034  O O     . ILE B 1 253 ? -32.036 27.356  -35.365  1.00 45.85  ? 253 ILE B O     1 
ATOM   6035  C CB    . ILE B 1 253 ? -30.239 28.485  -33.043  1.00 43.76  ? 253 ILE B CB    1 
ATOM   6036  C CG1   . ILE B 1 253 ? -29.361 27.559  -33.880  1.00 43.00  ? 253 ILE B CG1   1 
ATOM   6037  C CG2   . ILE B 1 253 ? -30.785 27.718  -31.868  1.00 43.68  ? 253 ILE B CG2   1 
ATOM   6038  C CD1   . ILE B 1 253 ? -28.873 28.124  -35.194  1.00 42.83  ? 253 ILE B CD1   1 
ATOM   6039  N N     . GLU B 1 254 ? -33.560 28.040  -33.831  1.00 44.84  ? 254 GLU B N     1 
ATOM   6040  C CA    . GLU B 1 254 ? -34.578 27.079  -34.227  1.00 44.10  ? 254 GLU B CA    1 
ATOM   6041  C C     . GLU B 1 254 ? -35.089 27.423  -35.626  1.00 44.85  ? 254 GLU B C     1 
ATOM   6042  O O     . GLU B 1 254 ? -34.856 26.697  -36.580  1.00 50.84  ? 254 GLU B O     1 
ATOM   6043  C CB    . GLU B 1 254 ? -35.677 27.051  -33.174  1.00 46.80  ? 254 GLU B CB    1 
ATOM   6044  C CG    . GLU B 1 254 ? -36.612 25.872  -33.329  1.00 56.99  ? 254 GLU B CG    1 
ATOM   6045  C CD    . GLU B 1 254 ? -37.720 25.783  -32.297  1.00 56.56  ? 254 GLU B CD    1 
ATOM   6046  O OE1   . GLU B 1 254 ? -37.652 26.475  -31.270  1.00 55.22  ? 254 GLU B OE1   1 
ATOM   6047  O OE2   . GLU B 1 254 ? -38.646 25.024  -32.543  1.00 66.72  ? 254 GLU B OE2   1 
ATOM   6048  N N     . THR B 1 255 ? -35.665 28.602  -35.788  1.00 44.71  ? 255 THR B N     1 
ATOM   6049  C CA    . THR B 1 255 ? -36.187 28.994  -37.083  1.00 48.54  ? 255 THR B CA    1 
ATOM   6050  C C     . THR B 1 255 ? -35.068 29.072  -38.127  1.00 44.85  ? 255 THR B C     1 
ATOM   6051  O O     . THR B 1 255 ? -35.276 28.790  -39.295  1.00 46.34  ? 255 THR B O     1 
ATOM   6052  C CB    . THR B 1 255 ? -36.996 30.284  -36.930  1.00 52.51  ? 255 THR B CB    1 
ATOM   6053  O OG1   . THR B 1 255 ? -37.858 30.390  -38.054  1.00 53.99  ? 255 THR B OG1   1 
ATOM   6054  C CG2   . THR B 1 255 ? -36.130 31.515  -36.835  1.00 63.15  ? 255 THR B CG2   1 
ATOM   6055  N N     . VAL B 1 256 ? -33.854 29.420  -37.714  1.00 46.37  ? 256 VAL B N     1 
ATOM   6056  C CA    . VAL B 1 256 ? -32.771 29.595  -38.657  1.00 42.53  ? 256 VAL B CA    1 
ATOM   6057  C C     . VAL B 1 256 ? -32.437 28.247  -39.278  1.00 42.66  ? 256 VAL B C     1 
ATOM   6058  O O     . VAL B 1 256 ? -32.209 28.181  -40.486  1.00 38.37  ? 256 VAL B O     1 
ATOM   6059  C CB    . VAL B 1 256 ? -31.552 30.275  -38.007  1.00 48.82  ? 256 VAL B CB    1 
ATOM   6060  C CG1   . VAL B 1 256 ? -30.246 29.973  -38.725  1.00 48.74  ? 256 VAL B CG1   1 
ATOM   6061  C CG2   . VAL B 1 256 ? -31.759 31.781  -37.920  1.00 46.20  ? 256 VAL B CG2   1 
ATOM   6062  N N     . THR B 1 257 ? -32.396 27.176  -38.466  1.00 50.35  ? 257 THR B N     1 
ATOM   6063  C CA    . THR B 1 257 ? -32.033 25.852  -38.979  1.00 40.73  ? 257 THR B CA    1 
ATOM   6064  C C     . THR B 1 257 ? -33.129 25.332  -39.911  1.00 36.29  ? 257 THR B C     1 
ATOM   6065  O O     . THR B 1 257 ? -32.818 24.810  -40.967  1.00 34.35  ? 257 THR B O     1 
ATOM   6066  C CB    . THR B 1 257 ? -31.770 24.859  -37.845  1.00 41.58  ? 257 THR B CB    1 
ATOM   6067  O OG1   . THR B 1 257 ? -30.719 25.370  -37.013  1.00 42.16  ? 257 THR B OG1   1 
ATOM   6068  C CG2   . THR B 1 257 ? -31.405 23.485  -38.374  1.00 40.12  ? 257 THR B CG2   1 
ATOM   6069  N N     . GLU B 1 258 ? -34.405 25.533  -39.544  1.00 34.51  ? 258 GLU B N     1 
ATOM   6070  C CA    . GLU B 1 258 ? -35.539 25.176  -40.396  1.00 43.30  ? 258 GLU B CA    1 
ATOM   6071  C C     . GLU B 1 258 ? -35.380 25.733  -41.813  1.00 42.64  ? 258 GLU B C     1 
ATOM   6072  O O     . GLU B 1 258 ? -35.673 25.024  -42.771  1.00 43.45  ? 258 GLU B O     1 
ATOM   6073  C CB    . GLU B 1 258 ? -36.901 25.654  -39.856  1.00 37.37  ? 258 GLU B CB    1 
ATOM   6074  C CG    . GLU B 1 258 ? -37.436 24.826  -38.702  1.00 38.30  ? 258 GLU B CG    1 
ATOM   6075  C CD    . GLU B 1 258 ? -37.710 23.361  -39.007  1.00 44.13  ? 258 GLU B CD    1 
ATOM   6076  O OE1   . GLU B 1 258 ? -38.751 23.060  -39.619  1.00 50.30  ? 258 GLU B OE1   1 
ATOM   6077  O OE2   . GLU B 1 258 ? -36.879 22.513  -38.636  1.00 46.78  ? 258 GLU B OE2   1 
ATOM   6078  N N     . ARG B 1 259 ? -34.984 27.008  -41.909  1.00 44.31  ? 259 ARG B N     1 
ATOM   6079  C CA    . ARG B 1 259 ? -34.888 27.734  -43.160  1.00 43.85  ? 259 ARG B CA    1 
ATOM   6080  C C     . ARG B 1 259 ? -33.598 27.382  -43.895  1.00 46.55  ? 259 ARG B C     1 
ATOM   6081  O O     . ARG B 1 259 ? -33.536 27.495  -45.115  1.00 45.88  ? 259 ARG B O     1 
ATOM   6082  C CB    . ARG B 1 259 ? -34.926 29.231  -42.868  1.00 45.14  ? 259 ARG B CB    1 
ATOM   6083  C CG    . ARG B 1 259 ? -36.248 29.697  -42.283  1.00 48.44  ? 259 ARG B CG    1 
ATOM   6084  C CD    . ARG B 1 259 ? -36.030 30.896  -41.377  1.00 52.99  ? 259 ARG B CD    1 
ATOM   6085  N NE    . ARG B 1 259 ? -37.268 31.370  -40.764  1.00 48.33  ? 259 ARG B NE    1 
ATOM   6086  C CZ    . ARG B 1 259 ? -37.906 32.464  -41.146  1.00 52.31  ? 259 ARG B CZ    1 
ATOM   6087  N NH1   . ARG B 1 259 ? -37.484 33.133  -42.197  1.00 55.93  ? 259 ARG B NH1   1 
ATOM   6088  N NH2   . ARG B 1 259 ? -38.975 32.885  -40.501  1.00 57.45  ? 259 ARG B NH2   1 
ATOM   6089  N N     . LEU B 1 260 ? -32.564 26.951  -43.167  1.00 41.48  ? 260 LEU B N     1 
ATOM   6090  C CA    . LEU B 1 260 ? -31.350 26.545  -43.844  1.00 42.67  ? 260 LEU B CA    1 
ATOM   6091  C C     . LEU B 1 260 ? -31.563 25.238  -44.604  1.00 42.79  ? 260 LEU B C     1 
ATOM   6092  O O     . LEU B 1 260 ? -30.918 25.018  -45.641  1.00 43.55  ? 260 LEU B O     1 
ATOM   6093  C CB    . LEU B 1 260 ? -30.210 26.419  -42.836  1.00 42.47  ? 260 LEU B CB    1 
ATOM   6094  C CG    . LEU B 1 260 ? -29.516 27.739  -42.519  1.00 50.73  ? 260 LEU B CG    1 
ATOM   6095  C CD1   . LEU B 1 260 ? -28.584 27.582  -41.320  1.00 49.89  ? 260 LEU B CD1   1 
ATOM   6096  C CD2   . LEU B 1 260 ? -28.749 28.267  -43.734  1.00 49.21  ? 260 LEU B CD2   1 
ATOM   6097  N N     . ARG B 1 261 ? -32.443 24.377  -44.066  1.00 43.63  ? 261 ARG B N     1 
ATOM   6098  C CA    . ARG B 1 261 ? -32.610 23.018  -44.574  1.00 47.69  ? 261 ARG B CA    1 
ATOM   6099  C C     . ARG B 1 261 ? -32.864 23.019  -46.093  1.00 45.85  ? 261 ARG B C     1 
ATOM   6100  O O     . ARG B 1 261 ? -32.030 22.498  -46.857  1.00 38.10  ? 261 ARG B O     1 
ATOM   6101  C CB    . ARG B 1 261 ? -33.698 22.270  -43.796  1.00 42.16  ? 261 ARG B CB    1 
ATOM   6102  C CG    . ARG B 1 261 ? -34.065 20.912  -44.388  1.00 40.45  ? 261 ARG B CG    1 
ATOM   6103  C CD    . ARG B 1 261 ? -35.141 20.127  -43.620  1.00 36.88  ? 261 ARG B CD    1 
ATOM   6104  N NE    . ARG B 1 261 ? -36.381 20.883  -43.408  1.00 36.59  ? 261 ARG B NE    1 
ATOM   6105  C CZ    . ARG B 1 261 ? -36.834 21.269  -42.208  1.00 41.61  ? 261 ARG B CZ    1 
ATOM   6106  N NH1   . ARG B 1 261 ? -36.196 20.911  -41.111  1.00 46.21  ? 261 ARG B NH1   1 
ATOM   6107  N NH2   . ARG B 1 261 ? -37.917 22.018  -42.078  1.00 39.66  ? 261 ARG B NH2   1 
ATOM   6108  N N     . PRO B 1 262 ? -33.997 23.578  -46.588  1.00 37.59  ? 262 PRO B N     1 
ATOM   6109  C CA    . PRO B 1 262 ? -34.327 23.509  -48.015  1.00 40.09  ? 262 PRO B CA    1 
ATOM   6110  C C     . PRO B 1 262 ? -33.197 24.045  -48.888  1.00 44.29  ? 262 PRO B C     1 
ATOM   6111  O O     . PRO B 1 262 ? -32.825 23.429  -49.892  1.00 46.36  ? 262 PRO B O     1 
ATOM   6112  C CB    . PRO B 1 262 ? -35.615 24.320  -48.214  1.00 34.34  ? 262 PRO B CB    1 
ATOM   6113  C CG    . PRO B 1 262 ? -35.923 24.931  -46.859  1.00 39.16  ? 262 PRO B CG    1 
ATOM   6114  C CD    . PRO B 1 262 ? -35.050 24.241  -45.816  1.00 38.23  ? 262 PRO B CD    1 
ATOM   6115  N N     . LEU B 1 263 ? -32.616 25.161  -48.444  1.00 47.16  ? 263 LEU B N     1 
ATOM   6116  C CA    . LEU B 1 263 ? -31.520 25.816  -49.148  1.00 48.43  ? 263 LEU B CA    1 
ATOM   6117  C C     . LEU B 1 263 ? -30.325 24.881  -49.308  1.00 49.01  ? 263 LEU B C     1 
ATOM   6118  O O     . LEU B 1 263 ? -29.602 24.916  -50.318  1.00 44.76  ? 263 LEU B O     1 
ATOM   6119  C CB    . LEU B 1 263 ? -31.141 27.065  -48.352  1.00 45.77  ? 263 LEU B CB    1 
ATOM   6120  C CG    . LEU B 1 263 ? -32.154 28.197  -48.473  1.00 46.61  ? 263 LEU B CG    1 
ATOM   6121  C CD1   . LEU B 1 263 ? -31.908 29.260  -47.419  1.00 48.08  ? 263 LEU B CD1   1 
ATOM   6122  C CD2   . LEU B 1 263 ? -32.088 28.793  -49.869  1.00 45.63  ? 263 LEU B CD2   1 
ATOM   6123  N N     . LYS B 1 264 ? -30.152 24.017  -48.309  1.00 47.16  ? 264 LYS B N     1 
ATOM   6124  C CA    . LYS B 1 264 ? -28.991 23.158  -48.275  1.00 46.54  ? 264 LYS B CA    1 
ATOM   6125  C C     . LYS B 1 264 ? -29.207 21.838  -49.031  1.00 45.91  ? 264 LYS B C     1 
ATOM   6126  O O     . LYS B 1 264 ? -28.284 21.353  -49.701  1.00 40.85  ? 264 LYS B O     1 
ATOM   6127  C CB    . LYS B 1 264 ? -28.623 22.985  -46.810  1.00 50.02  ? 264 LYS B CB    1 
ATOM   6128  C CG    . LYS B 1 264 ? -27.154 22.698  -46.606  1.00 54.60  ? 264 LYS B CG    1 
ATOM   6129  C CD    . LYS B 1 264 ? -26.277 23.865  -46.907  1.00 49.95  ? 264 LYS B CD    1 
ATOM   6130  C CE    . LYS B 1 264 ? -24.855 23.399  -47.147  1.00 54.25  ? 264 LYS B CE    1 
ATOM   6131  N NZ    . LYS B 1 264 ? -24.637 22.848  -48.503  1.00 51.84  ? 264 LYS B NZ    1 
ATOM   6132  N N     . VAL B 1 265 ? -30.411 21.248  -48.940  1.00 45.11  ? 265 VAL B N     1 
ATOM   6133  C CA    . VAL B 1 265 ? -30.672 19.974  -49.600  1.00 45.62  ? 265 VAL B CA    1 
ATOM   6134  C C     . VAL B 1 265 ? -30.645 20.177  -51.120  1.00 50.74  ? 265 VAL B C     1 
ATOM   6135  O O     . VAL B 1 265 ? -30.084 19.350  -51.846  1.00 46.14  ? 265 VAL B O     1 
ATOM   6136  C CB    . VAL B 1 265 ? -32.005 19.356  -49.133  1.00 45.06  ? 265 VAL B CB    1 
ATOM   6137  C CG1   . VAL B 1 265 ? -32.404 18.160  -49.985  1.00 39.37  ? 265 VAL B CG1   1 
ATOM   6138  C CG2   . VAL B 1 265 ? -31.971 18.979  -47.649  1.00 47.26  ? 265 VAL B CG2   1 
ATOM   6139  N N     . ALA B 1 266 ? -31.204 21.313  -51.578  1.00 48.32  ? 266 ALA B N     1 
ATOM   6140  C CA    . ALA B 1 266 ? -31.289 21.633  -52.994  1.00 49.04  ? 266 ALA B CA    1 
ATOM   6141  C C     . ALA B 1 266 ? -29.999 22.228  -53.564  1.00 51.41  ? 266 ALA B C     1 
ATOM   6142  O O     . ALA B 1 266 ? -29.916 22.420  -54.766  1.00 55.34  ? 266 ALA B O     1 
ATOM   6143  C CB    . ALA B 1 266 ? -32.448 22.569  -53.199  1.00 51.28  ? 266 ALA B CB    1 
ATOM   6144  N N     . GLY B 1 267 ? -28.993 22.532  -52.734  1.00 51.15  ? 267 GLY B N     1 
ATOM   6145  C CA    . GLY B 1 267 ? -27.723 23.054  -53.228  1.00 52.03  ? 267 GLY B CA    1 
ATOM   6146  C C     . GLY B 1 267 ? -27.723 24.557  -53.567  1.00 54.52  ? 267 GLY B C     1 
ATOM   6147  O O     . GLY B 1 267 ? -26.857 25.032  -54.295  1.00 53.46  ? 267 GLY B O     1 
ATOM   6148  N N     . VAL B 1 268 ? -28.670 25.322  -53.021  1.00 55.49  ? 268 VAL B N     1 
ATOM   6149  C CA    . VAL B 1 268 ? -28.735 26.755  -53.249  1.00 57.77  ? 268 VAL B CA    1 
ATOM   6150  C C     . VAL B 1 268 ? -27.602 27.442  -52.485  1.00 62.39  ? 268 VAL B C     1 
ATOM   6151  O O     . VAL B 1 268 ? -27.048 28.435  -52.943  1.00 74.22  ? 268 VAL B O     1 
ATOM   6152  C CB    . VAL B 1 268 ? -30.111 27.294  -52.820  1.00 59.08  ? 268 VAL B CB    1 
ATOM   6153  C CG1   . VAL B 1 268 ? -30.174 28.810  -52.863  1.00 61.24  ? 268 VAL B CG1   1 
ATOM   6154  C CG2   . VAL B 1 268 ? -31.229 26.679  -53.653  1.00 55.74  ? 268 VAL B CG2   1 
ATOM   6155  N N     . ILE B 1 269 ? -27.286 26.941  -51.291  1.00 52.86  ? 269 ILE B N     1 
ATOM   6156  C CA    . ILE B 1 269 ? -26.120 27.389  -50.564  1.00 46.16  ? 269 ILE B CA    1 
ATOM   6157  C C     . ILE B 1 269 ? -24.977 26.444  -50.929  1.00 49.26  ? 269 ILE B C     1 
ATOM   6158  O O     . ILE B 1 269 ? -25.029 25.255  -50.658  1.00 50.85  ? 269 ILE B O     1 
ATOM   6159  C CB    . ILE B 1 269 ? -26.436 27.410  -49.058  1.00 48.54  ? 269 ILE B CB    1 
ATOM   6160  C CG1   . ILE B 1 269 ? -27.353 28.577  -48.706  1.00 47.02  ? 269 ILE B CG1   1 
ATOM   6161  C CG2   . ILE B 1 269 ? -25.167 27.412  -48.216  1.00 43.56  ? 269 ILE B CG2   1 
ATOM   6162  C CD1   . ILE B 1 269 ? -27.868 28.515  -47.287  1.00 47.46  ? 269 ILE B CD1   1 
ATOM   6163  N N     . GLN B 1 270 ? -23.942 26.983  -51.569  1.00 50.74  ? 270 GLN B N     1 
ATOM   6164  C CA    . GLN B 1 270 ? -23.020 26.174  -52.344  1.00 50.59  ? 270 GLN B CA    1 
ATOM   6165  C C     . GLN B 1 270 ? -21.935 25.593  -51.443  1.00 48.18  ? 270 GLN B C     1 
ATOM   6166  O O     . GLN B 1 270 ? -21.333 24.598  -51.787  1.00 47.26  ? 270 GLN B O     1 
ATOM   6167  C CB    . GLN B 1 270 ? -22.419 27.023  -53.474  1.00 49.64  ? 270 GLN B CB    1 
ATOM   6168  C CG    . GLN B 1 270 ? -23.458 27.510  -54.466  1.00 48.29  ? 270 GLN B CG    1 
ATOM   6169  C CD    . GLN B 1 270 ? -23.085 28.829  -55.099  1.00 50.99  ? 270 GLN B CD    1 
ATOM   6170  O OE1   . GLN B 1 270 ? -23.276 29.911  -54.541  1.00 48.41  ? 270 GLN B OE1   1 
ATOM   6171  N NE2   . GLN B 1 270 ? -22.583 28.747  -56.311  1.00 52.92  ? 270 GLN B NE2   1 
ATOM   6172  N N     . ASN B 1 271 ? -21.643 26.230  -50.309  1.00 51.07  ? 271 ASN B N     1 
ATOM   6173  C CA    . ASN B 1 271 ? -20.664 25.672  -49.392  1.00 48.94  ? 271 ASN B CA    1 
ATOM   6174  C C     . ASN B 1 271 ? -21.368 25.144  -48.143  1.00 46.07  ? 271 ASN B C     1 
ATOM   6175  O O     . ASN B 1 271 ? -22.590 25.232  -48.022  1.00 47.53  ? 271 ASN B O     1 
ATOM   6176  C CB    . ASN B 1 271 ? -19.544 26.671  -49.080  1.00 51.24  ? 271 ASN B CB    1 
ATOM   6177  C CG    . ASN B 1 271 ? -19.998 27.969  -48.446  1.00 49.42  ? 271 ASN B CG    1 
ATOM   6178  O OD1   . ASN B 1 271 ? -21.168 28.363  -48.515  1.00 42.81  ? 271 ASN B OD1   1 
ATOM   6179  N ND2   . ASN B 1 271 ? -19.040 28.649  -47.830  1.00 50.65  ? 271 ASN B ND2   1 
ATOM   6180  N N     . GLY B 1 272 ? -20.582 24.546  -47.236  1.00 43.92  ? 272 GLY B N     1 
ATOM   6181  C CA    . GLY B 1 272 ? -21.013 24.340  -45.860  1.00 43.21  ? 272 GLY B CA    1 
ATOM   6182  C C     . GLY B 1 272 ? -21.561 25.629  -45.239  1.00 43.33  ? 272 GLY B C     1 
ATOM   6183  O O     . GLY B 1 272 ? -20.944 26.683  -45.323  1.00 42.99  ? 272 GLY B O     1 
ATOM   6184  N N     . ALA B 1 273 ? -22.777 25.546  -44.705  1.00 41.50  ? 273 ALA B N     1 
ATOM   6185  C CA    . ALA B 1 273 ? -23.359 26.617  -43.936  1.00 44.91  ? 273 ALA B CA    1 
ATOM   6186  C C     . ALA B 1 273 ? -22.948 26.459  -42.474  1.00 46.49  ? 273 ALA B C     1 
ATOM   6187  O O     . ALA B 1 273 ? -23.246 25.449  -41.834  1.00 42.80  ? 273 ALA B O     1 
ATOM   6188  C CB    . ALA B 1 273 ? -24.863 26.589  -44.074  1.00 46.40  ? 273 ALA B CB    1 
ATOM   6189  N N     . THR B 1 274 ? -22.346 27.526  -41.945  1.00 48.80  ? 274 THR B N     1 
ATOM   6190  C CA    . THR B 1 274 ? -21.922 27.593  -40.561  1.00 49.48  ? 274 THR B CA    1 
ATOM   6191  C C     . THR B 1 274 ? -22.697 28.704  -39.855  1.00 42.99  ? 274 THR B C     1 
ATOM   6192  O O     . THR B 1 274 ? -22.724 29.818  -40.342  1.00 48.32  ? 274 THR B O     1 
ATOM   6193  C CB    . THR B 1 274 ? -20.401 27.795  -40.538  1.00 54.91  ? 274 THR B CB    1 
ATOM   6194  O OG1   . THR B 1 274 ? -20.097 28.818  -41.482  1.00 61.91  ? 274 THR B OG1   1 
ATOM   6195  C CG2   . THR B 1 274 ? -19.625 26.569  -40.961  1.00 63.02  ? 274 THR B CG2   1 
ATOM   6196  N N     . VAL B 1 275 ? -23.264 28.427  -38.674  1.00 42.25  ? 275 VAL B N     1 
ATOM   6197  C CA    . VAL B 1 275 ? -23.893 29.463  -37.862  1.00 44.81  ? 275 VAL B CA    1 
ATOM   6198  C C     . VAL B 1 275 ? -23.279 29.431  -36.470  1.00 46.58  ? 275 VAL B C     1 
ATOM   6199  O O     . VAL B 1 275 ? -23.618 28.550  -35.680  1.00 45.15  ? 275 VAL B O     1 
ATOM   6200  C CB    . VAL B 1 275 ? -25.414 29.268  -37.740  1.00 43.88  ? 275 VAL B CB    1 
ATOM   6201  C CG1   . VAL B 1 275 ? -26.053 30.381  -36.938  1.00 44.70  ? 275 VAL B CG1   1 
ATOM   6202  C CG2   . VAL B 1 275 ? -26.085 29.129  -39.086  1.00 39.35  ? 275 VAL B CG2   1 
ATOM   6203  N N     . ARG B 1 276 ? -22.427 30.425  -36.186  1.00 46.15  ? 276 ARG B N     1 
ATOM   6204  C CA    . ARG B 1 276 ? -21.578 30.436  -35.004  1.00 45.22  ? 276 ARG B CA    1 
ATOM   6205  C C     . ARG B 1 276 ? -22.184 31.302  -33.905  1.00 43.78  ? 276 ARG B C     1 
ATOM   6206  O O     . ARG B 1 276 ? -22.912 32.248  -34.182  1.00 49.73  ? 276 ARG B O     1 
ATOM   6207  C CB    . ARG B 1 276 ? -20.180 30.955  -35.345  1.00 51.50  ? 276 ARG B CB    1 
ATOM   6208  C CG    . ARG B 1 276 ? -19.363 29.992  -36.199  1.00 55.65  ? 276 ARG B CG    1 
ATOM   6209  C CD    . ARG B 1 276 ? -18.117 30.600  -36.808  1.00 57.60  ? 276 ARG B CD    1 
ATOM   6210  N NE    . ARG B 1 276 ? -17.157 29.569  -37.142  1.00 61.44  ? 276 ARG B NE    1 
ATOM   6211  C CZ    . ARG B 1 276 ? -17.074 28.998  -38.334  1.00 68.79  ? 276 ARG B CZ    1 
ATOM   6212  N NH1   . ARG B 1 276 ? -17.896 29.393  -39.291  1.00 67.48  ? 276 ARG B NH1   1 
ATOM   6213  N NH2   . ARG B 1 276 ? -16.189 28.033  -38.555  1.00 71.62  ? 276 ARG B NH2   1 
ATOM   6214  N N     . SER B 1 277 ? -21.884 30.930  -32.657  1.00 42.00  ? 277 SER B N     1 
ATOM   6215  C CA    . SER B 1 277 ? -22.373 31.634  -31.484  1.00 40.37  ? 277 SER B CA    1 
ATOM   6216  C C     . SER B 1 277 ? -21.464 32.812  -31.189  1.00 41.67  ? 277 SER B C     1 
ATOM   6217  O O     . SER B 1 277 ? -20.289 32.792  -31.561  1.00 38.93  ? 277 SER B O     1 
ATOM   6218  C CB    . SER B 1 277 ? -22.456 30.733  -30.288  1.00 37.34  ? 277 SER B CB    1 
ATOM   6219  O OG    . SER B 1 277 ? -21.165 30.363  -29.864  1.00 35.08  ? 277 SER B OG    1 
ATOM   6220  N N     . LEU B 1 278 ? -22.045 33.786  -30.472  1.00 42.91  ? 278 LEU B N     1 
ATOM   6221  C CA    . LEU B 1 278 ? -21.434 35.070  -30.188  1.00 48.89  ? 278 LEU B CA    1 
ATOM   6222  C C     . LEU B 1 278 ? -19.977 34.893  -29.769  1.00 47.23  ? 278 LEU B C     1 
ATOM   6223  O O     . LEU B 1 278 ? -19.099 35.537  -30.347  1.00 43.84  ? 278 LEU B O     1 
ATOM   6224  C CB    . LEU B 1 278 ? -22.226 35.792  -29.091  1.00 56.26  ? 278 LEU B CB    1 
ATOM   6225  C CG    . LEU B 1 278 ? -21.486 36.954  -28.414  1.00 54.62  ? 278 LEU B CG    1 
ATOM   6226  C CD1   . LEU B 1 278 ? -21.252 38.090  -29.400  1.00 54.45  ? 278 LEU B CD1   1 
ATOM   6227  C CD2   . LEU B 1 278 ? -22.248 37.451  -27.199  1.00 56.55  ? 278 LEU B CD2   1 
ATOM   6228  N N     . VAL B 1 279 ? -19.747 34.035  -28.770  1.00 44.34  ? 279 VAL B N     1 
ATOM   6229  C CA    . VAL B 1 279 ? -18.445 33.947  -28.131  1.00 45.68  ? 279 VAL B CA    1 
ATOM   6230  C C     . VAL B 1 279 ? -17.425 33.338  -29.087  1.00 46.83  ? 279 VAL B C     1 
ATOM   6231  O O     . VAL B 1 279 ? -16.242 33.686  -29.037  1.00 54.41  ? 279 VAL B O     1 
ATOM   6232  C CB    . VAL B 1 279 ? -18.491 33.195  -26.782  1.00 46.46  ? 279 VAL B CB    1 
ATOM   6233  C CG1   . VAL B 1 279 ? -17.108 32.925  -26.211  1.00 49.65  ? 279 VAL B CG1   1 
ATOM   6234  C CG2   . VAL B 1 279 ? -19.301 33.964  -25.755  1.00 47.73  ? 279 VAL B CG2   1 
ATOM   6235  N N     . LEU B 1 280 ? -17.860 32.438  -29.966  1.00 50.33  ? 280 LEU B N     1 
ATOM   6236  C CA    . LEU B 1 280 ? -16.894 31.708  -30.775  1.00 46.53  ? 280 LEU B CA    1 
ATOM   6237  C C     . LEU B 1 280 ? -16.393 32.637  -31.875  1.00 43.32  ? 280 LEU B C     1 
ATOM   6238  O O     . LEU B 1 280 ? -15.186 32.652  -32.173  1.00 43.67  ? 280 LEU B O     1 
ATOM   6239  C CB    . LEU B 1 280 ? -17.505 30.412  -31.317  1.00 43.07  ? 280 LEU B CB    1 
ATOM   6240  C CG    . LEU B 1 280 ? -16.682 29.679  -32.373  1.00 42.26  ? 280 LEU B CG    1 
ATOM   6241  C CD1   . LEU B 1 280 ? -15.378 29.134  -31.827  1.00 42.52  ? 280 LEU B CD1   1 
ATOM   6242  C CD2   . LEU B 1 280 ? -17.489 28.553  -32.949  1.00 45.81  ? 280 LEU B CD2   1 
ATOM   6243  N N     . ASP B 1 281 ? -17.312 33.465  -32.388  1.00 39.74  ? 281 ASP B N     1 
ATOM   6244  C CA    . ASP B 1 281 ? -16.953 34.555  -33.290  1.00 45.16  ? 281 ASP B CA    1 
ATOM   6245  C C     . ASP B 1 281 ? -16.130 35.647  -32.599  1.00 49.10  ? 281 ASP B C     1 
ATOM   6246  O O     . ASP B 1 281 ? -15.056 36.013  -33.092  1.00 49.57  ? 281 ASP B O     1 
ATOM   6247  C CB    . ASP B 1 281 ? -18.191 35.101  -33.996  1.00 43.32  ? 281 ASP B CB    1 
ATOM   6248  C CG    . ASP B 1 281 ? -18.498 34.211  -35.192  1.00 47.95  ? 281 ASP B CG    1 
ATOM   6249  O OD1   . ASP B 1 281 ? -17.708 33.241  -35.384  1.00 43.78  ? 281 ASP B OD1   1 
ATOM   6250  O OD2   . ASP B 1 281 ? -19.530 34.450  -35.894  1.00 45.85  ? 281 ASP B OD2   1 
ATOM   6251  N N     . ALA B 1 282 ? -16.632 36.162  -31.471  1.00 46.20  ? 282 ALA B N     1 
ATOM   6252  C CA    . ALA B 1 282 ? -15.932 37.202  -30.735  1.00 47.70  ? 282 ALA B CA    1 
ATOM   6253  C C     . ALA B 1 282 ? -14.508 36.769  -30.411  1.00 46.29  ? 282 ALA B C     1 
ATOM   6254  O O     . ALA B 1 282 ? -13.600 37.585  -30.380  1.00 41.41  ? 282 ALA B O     1 
ATOM   6255  C CB    . ALA B 1 282 ? -16.666 37.534  -29.472  1.00 49.29  ? 282 ALA B CB    1 
ATOM   6256  N N     . ALA B 1 283 ? -14.302 35.476  -30.151  1.00 51.84  ? 283 ALA B N     1 
ATOM   6257  C CA    . ALA B 1 283 ? -13.006 35.024  -29.671  1.00 47.07  ? 283 ALA B CA    1 
ATOM   6258  C C     . ALA B 1 283 ? -11.949 35.125  -30.774  1.00 45.97  ? 283 ALA B C     1 
ATOM   6259  O O     . ALA B 1 283 ? -10.764 34.921  -30.509  1.00 48.76  ? 283 ALA B O     1 
ATOM   6260  C CB    . ALA B 1 283 ? -13.120 33.636  -29.110  1.00 43.97  ? 283 ALA B CB    1 
ATOM   6261  N N     . ILE B 1 284 ? -12.379 35.482  -31.992  1.00 49.07  ? 284 ILE B N     1 
ATOM   6262  C CA    . ILE B 1 284 ? -11.454 35.653  -33.099  1.00 53.00  ? 284 ILE B CA    1 
ATOM   6263  C C     . ILE B 1 284 ? -10.695 36.960  -32.902  1.00 50.96  ? 284 ILE B C     1 
ATOM   6264  O O     . ILE B 1 284 ? -9.507  36.972  -33.206  1.00 54.07  ? 284 ILE B O     1 
ATOM   6265  C CB    . ILE B 1 284 ? -12.140 35.589  -34.486  1.00 60.41  ? 284 ILE B CB    1 
ATOM   6266  C CG1   . ILE B 1 284 ? -12.735 34.209  -34.776  1.00 55.67  ? 284 ILE B CG1   1 
ATOM   6267  C CG2   . ILE B 1 284 ? -11.165 36.005  -35.589  1.00 62.45  ? 284 ILE B CG2   1 
ATOM   6268  C CD1   . ILE B 1 284 ? -11.795 33.050  -34.395  1.00 60.38  ? 284 ILE B CD1   1 
ATOM   6269  N N     . THR B 1 285 ? -11.353 38.007  -32.357  1.00 45.66  ? 285 THR B N     1 
ATOM   6270  C CA    . THR B 1 285 ? -10.743 39.327  -32.280  1.00 47.59  ? 285 THR B CA    1 
ATOM   6271  C C     . THR B 1 285 ? -10.682 39.914  -30.868  1.00 50.02  ? 285 THR B C     1 
ATOM   6272  O O     . THR B 1 285 ? -10.260 41.050  -30.739  1.00 48.08  ? 285 THR B O     1 
ATOM   6273  C CB    . THR B 1 285 ? -11.421 40.333  -33.217  1.00 50.80  ? 285 THR B CB    1 
ATOM   6274  O OG1   . THR B 1 285 ? -12.628 40.812  -32.634  1.00 51.27  ? 285 THR B OG1   1 
ATOM   6275  C CG2   . THR B 1 285 ? -11.694 39.773  -34.600  1.00 47.69  ? 285 THR B CG2   1 
ATOM   6276  N N     . ARG B 1 286 ? -11.039 39.149  -29.825  1.00 50.75  ? 286 ARG B N     1 
ATOM   6277  C CA    . ARG B 1 286 ? -11.192 39.663  -28.470  1.00 46.64  ? 286 ARG B CA    1 
ATOM   6278  C C     . ARG B 1 286 ? -11.013 38.540  -27.447  1.00 46.65  ? 286 ARG B C     1 
ATOM   6279  O O     . ARG B 1 286 ? -11.124 37.366  -27.792  1.00 48.91  ? 286 ARG B O     1 
ATOM   6280  C CB    . ARG B 1 286 ? -12.582 40.273  -28.259  1.00 48.99  ? 286 ARG B CB    1 
ATOM   6281  C CG    . ARG B 1 286 ? -12.899 41.465  -29.154  1.00 50.09  ? 286 ARG B CG    1 
ATOM   6282  C CD    . ARG B 1 286 ? -12.135 42.734  -28.795  1.00 51.39  ? 286 ARG B CD    1 
ATOM   6283  N NE    . ARG B 1 286 ? -12.636 43.919  -29.499  1.00 51.89  ? 286 ARG B NE    1 
ATOM   6284  C CZ    . ARG B 1 286 ? -12.336 44.255  -30.760  1.00 42.22  ? 286 ARG B CZ    1 
ATOM   6285  N NH1   . ARG B 1 286 ? -11.420 43.589  -31.432  1.00 36.65  ? 286 ARG B NH1   1 
ATOM   6286  N NH2   . ARG B 1 286 ? -12.935 45.280  -31.344  1.00 42.97  ? 286 ARG B NH2   1 
ATOM   6287  N N     . THR B 1 287 ? -10.748 38.911  -26.180  1.00 47.97  ? 287 THR B N     1 
ATOM   6288  C CA    . THR B 1 287 ? -10.595 37.950  -25.097  1.00 44.57  ? 287 THR B CA    1 
ATOM   6289  C C     . THR B 1 287 ? -11.648 38.219  -24.028  1.00 44.04  ? 287 THR B C     1 
ATOM   6290  O O     . THR B 1 287 ? -12.202 39.302  -23.994  1.00 45.19  ? 287 THR B O     1 
ATOM   6291  C CB    . THR B 1 287 ? -9.173  37.949  -24.512  1.00 46.39  ? 287 THR B CB    1 
ATOM   6292  O OG1   . THR B 1 287 ? -8.970  39.199  -23.850  1.00 56.14  ? 287 THR B OG1   1 
ATOM   6293  C CG2   . THR B 1 287 ? -8.103  37.723  -25.553  1.00 46.11  ? 287 THR B CG2   1 
ATOM   6294  N N     . LYS B 1 288 ? -11.908 37.214  -23.172  1.00 46.87  ? 288 LYS B N     1 
ATOM   6295  C CA    . LYS B 1 288 ? -12.862 37.332  -22.082  1.00 49.60  ? 288 LYS B CA    1 
ATOM   6296  C C     . LYS B 1 288 ? -12.493 38.512  -21.176  1.00 44.20  ? 288 LYS B C     1 
ATOM   6297  O O     . LYS B 1 288 ? -13.357 39.291  -20.787  1.00 41.83  ? 288 LYS B O     1 
ATOM   6298  C CB    . LYS B 1 288 ? -12.941 36.047  -21.233  1.00 50.84  ? 288 LYS B CB    1 
ATOM   6299  C CG    . LYS B 1 288 ? -13.975 36.141  -20.109  1.00 51.31  ? 288 LYS B CG    1 
ATOM   6300  C CD    . LYS B 1 288 ? -14.457 34.887  -19.405  1.00 46.71  ? 288 LYS B CD    1 
ATOM   6301  C CE    . LYS B 1 288 ? -13.494 34.353  -18.374  1.00 52.93  ? 288 LYS B CE    1 
ATOM   6302  N NZ    . LYS B 1 288 ? -14.206 33.594  -17.320  1.00 54.73  ? 288 LYS B NZ    1 
ATOM   6303  N N     . SER B 1 289 ? -11.209 38.635  -20.834  1.00 45.35  ? 289 SER B N     1 
ATOM   6304  C CA    . SER B 1 289 ? -10.779 39.523  -19.760  1.00 47.11  ? 289 SER B CA    1 
ATOM   6305  C C     . SER B 1 289 ? -10.846 40.980  -20.208  1.00 43.43  ? 289 SER B C     1 
ATOM   6306  O O     . SER B 1 289 ? -10.800 41.872  -19.382  1.00 49.25  ? 289 SER B O     1 
ATOM   6307  C CB    . SER B 1 289 ? -9.401  39.179  -19.298  1.00 46.33  ? 289 SER B CB    1 
ATOM   6308  O OG    . SER B 1 289 ? -8.503  39.450  -20.353  1.00 52.59  ? 289 SER B OG    1 
ATOM   6309  N N     . GLN B 1 290 ? -11.032 41.202  -21.504  1.00 40.80  ? 290 GLN B N     1 
ATOM   6310  C CA    . GLN B 1 290 ? -11.381 42.512  -22.024  1.00 39.82  ? 290 GLN B CA    1 
ATOM   6311  C C     . GLN B 1 290 ? -12.866 42.851  -21.870  1.00 40.15  ? 290 GLN B C     1 
ATOM   6312  O O     . GLN B 1 290 ? -13.236 43.997  -22.152  1.00 43.35  ? 290 GLN B O     1 
ATOM   6313  C CB    . GLN B 1 290 ? -10.990 42.578  -23.500  1.00 38.54  ? 290 GLN B CB    1 
ATOM   6314  C CG    . GLN B 1 290 ? -9.491  42.397  -23.727  1.00 39.04  ? 290 GLN B CG    1 
ATOM   6315  C CD    . GLN B 1 290 ? -9.181  42.198  -25.191  1.00 46.65  ? 290 GLN B CD    1 
ATOM   6316  O OE1   . GLN B 1 290 ? -10.067 42.014  -26.023  1.00 48.43  ? 290 GLN B OE1   1 
ATOM   6317  N NE2   . GLN B 1 290 ? -7.907  42.214  -25.523  1.00 52.69  ? 290 GLN B NE2   1 
ATOM   6318  N N     . TYR B 1 291 ? -13.731 41.900  -21.458  1.00 40.70  ? 291 TYR B N     1 
ATOM   6319  C CA    . TYR B 1 291 ? -15.156 42.228  -21.299  1.00 42.15  ? 291 TYR B CA    1 
ATOM   6320  C C     . TYR B 1 291 ? -15.737 41.844  -19.943  1.00 41.68  ? 291 TYR B C     1 
ATOM   6321  O O     . TYR B 1 291 ? -16.790 42.349  -19.588  1.00 45.54  ? 291 TYR B O     1 
ATOM   6322  C CB    . TYR B 1 291 ? -16.006 41.562  -22.374  1.00 40.64  ? 291 TYR B CB    1 
ATOM   6323  C CG    . TYR B 1 291 ? -16.048 42.294  -23.688  1.00 38.73  ? 291 TYR B CG    1 
ATOM   6324  C CD1   . TYR B 1 291 ? -16.900 43.373  -23.869  1.00 38.77  ? 291 TYR B CD1   1 
ATOM   6325  C CD2   . TYR B 1 291 ? -15.232 41.925  -24.742  1.00 39.45  ? 291 TYR B CD2   1 
ATOM   6326  C CE1   . TYR B 1 291 ? -16.960 44.058  -25.071  1.00 41.53  ? 291 TYR B CE1   1 
ATOM   6327  C CE2   . TYR B 1 291 ? -15.254 42.628  -25.948  1.00 42.37  ? 291 TYR B CE2   1 
ATOM   6328  C CZ    . TYR B 1 291 ? -16.139 43.678  -26.121  1.00 44.94  ? 291 TYR B CZ    1 
ATOM   6329  O OH    . TYR B 1 291 ? -16.174 44.374  -27.303  1.00 54.65  ? 291 TYR B OH    1 
ATOM   6330  N N     . TYR B 1 292 ? -15.045 40.983  -19.180  1.00 50.86  ? 292 TYR B N     1 
ATOM   6331  C CA    . TYR B 1 292 ? -15.552 40.465  -17.916  1.00 48.55  ? 292 TYR B CA    1 
ATOM   6332  C C     . TYR B 1 292 ? -14.377 40.012  -17.053  1.00 53.86  ? 292 TYR B C     1 
ATOM   6333  O O     . TYR B 1 292 ? -13.413 39.436  -17.552  1.00 47.35  ? 292 TYR B O     1 
ATOM   6334  C CB    . TYR B 1 292 ? -16.546 39.331  -18.183  1.00 52.63  ? 292 TYR B CB    1 
ATOM   6335  C CG    . TYR B 1 292 ? -17.199 38.728  -16.968  1.00 53.53  ? 292 TYR B CG    1 
ATOM   6336  C CD1   . TYR B 1 292 ? -17.938 39.511  -16.091  1.00 50.17  ? 292 TYR B CD1   1 
ATOM   6337  C CD2   . TYR B 1 292 ? -17.096 37.366  -16.706  1.00 47.74  ? 292 TYR B CD2   1 
ATOM   6338  C CE1   . TYR B 1 292 ? -18.541 38.962  -14.969  1.00 47.54  ? 292 TYR B CE1   1 
ATOM   6339  C CE2   . TYR B 1 292 ? -17.696 36.806  -15.592  1.00 48.37  ? 292 TYR B CE2   1 
ATOM   6340  C CZ    . TYR B 1 292 ? -18.425 37.607  -14.727  1.00 49.81  ? 292 TYR B CZ    1 
ATOM   6341  O OH    . TYR B 1 292 ? -19.026 37.065  -13.626  1.00 55.14  ? 292 TYR B OH    1 
ATOM   6342  N N     . ASP B 1 293 ? -14.490 40.289  -15.749  1.00 66.14  ? 293 ASP B N     1 
ATOM   6343  C CA    . ASP B 1 293 ? -13.411 40.082  -14.805  1.00 64.20  ? 293 ASP B CA    1 
ATOM   6344  C C     . ASP B 1 293 ? -13.602 38.762  -14.052  1.00 67.47  ? 293 ASP B C     1 
ATOM   6345  O O     . ASP B 1 293 ? -12.661 38.290  -13.430  1.00 76.84  ? 293 ASP B O     1 
ATOM   6346  C CB    . ASP B 1 293 ? -13.326 41.269  -13.838  1.00 68.62  ? 293 ASP B CB    1 
ATOM   6347  C CG    . ASP B 1 293 ? -11.894 41.689  -13.539  1.00 84.34  ? 293 ASP B CG    1 
ATOM   6348  O OD1   . ASP B 1 293 ? -11.069 40.794  -13.175  1.00 77.95  ? 293 ASP B OD1   1 
ATOM   6349  O OD2   . ASP B 1 293 ? -11.591 42.900  -13.714  1.00 88.12  ? 293 ASP B OD2   1 
ATOM   6350  N N     . GLY B 1 294 ? -14.807 38.167  -14.098  1.00 69.77  ? 294 GLY B N     1 
ATOM   6351  C CA    . GLY B 1 294 ? -15.157 37.010  -13.277  1.00 61.96  ? 294 GLY B CA    1 
ATOM   6352  C C     . GLY B 1 294 ? -14.499 35.715  -13.754  1.00 58.60  ? 294 GLY B C     1 
ATOM   6353  O O     . GLY B 1 294 ? -14.022 35.647  -14.889  1.00 52.44  ? 294 GLY B O     1 
ATOM   6354  N N     . ASP B 1 295 ? -14.482 34.695  -12.872  1.00 59.27  ? 295 ASP B N     1 
ATOM   6355  C CA    . ASP B 1 295 ? -13.868 33.403  -13.173  1.00 62.14  ? 295 ASP B CA    1 
ATOM   6356  C C     . ASP B 1 295 ? -14.827 32.557  -14.016  1.00 60.86  ? 295 ASP B C     1 
ATOM   6357  O O     . ASP B 1 295 ? -14.396 31.683  -14.778  1.00 54.07  ? 295 ASP B O     1 
ATOM   6358  C CB    . ASP B 1 295 ? -13.425 32.661  -11.904  1.00 67.14  ? 295 ASP B CB    1 
ATOM   6359  C CG    . ASP B 1 295 ? -12.166 33.216  -11.244  1.00 84.98  ? 295 ASP B CG    1 
ATOM   6360  O OD1   . ASP B 1 295 ? -11.188 33.539  -11.974  1.00 81.30  ? 295 ASP B OD1   1 
ATOM   6361  O OD2   . ASP B 1 295 ? -12.144 33.291  -9.994   1.00 86.80  ? 295 ASP B OD2   1 
ATOM   6362  N N     . GLY B 1 296 ? -16.132 32.837  -13.874  1.00 56.09  ? 296 GLY B N     1 
ATOM   6363  C CA    . GLY B 1 296 ? -17.178 32.067  -14.518  1.00 52.83  ? 296 GLY B CA    1 
ATOM   6364  C C     . GLY B 1 296 ? -17.418 32.523  -15.955  1.00 57.77  ? 296 GLY B C     1 
ATOM   6365  O O     . GLY B 1 296 ? -16.683 33.329  -16.528  1.00 60.06  ? 296 GLY B O     1 
ATOM   6366  N N     . PRO B 1 297 ? -18.479 32.013  -16.592  1.00 49.86  ? 297 PRO B N     1 
ATOM   6367  C CA    . PRO B 1 297 ? -18.786 32.398  -17.959  1.00 51.71  ? 297 PRO B CA    1 
ATOM   6368  C C     . PRO B 1 297 ? -19.479 33.746  -17.913  1.00 50.40  ? 297 PRO B C     1 
ATOM   6369  O O     . PRO B 1 297 ? -19.954 34.152  -16.853  1.00 55.12  ? 297 PRO B O     1 
ATOM   6370  C CB    . PRO B 1 297 ? -19.737 31.282  -18.406  1.00 58.32  ? 297 PRO B CB    1 
ATOM   6371  C CG    . PRO B 1 297 ? -20.487 30.921  -17.118  1.00 52.99  ? 297 PRO B CG    1 
ATOM   6372  C CD    . PRO B 1 297 ? -19.447 31.063  -16.027  1.00 50.17  ? 297 PRO B CD    1 
ATOM   6373  N N     . ILE B 1 298 ? -19.607 34.360  -19.089  1.00 43.66  ? 298 ILE B N     1 
ATOM   6374  C CA    . ILE B 1 298 ? -20.027 35.739  -19.206  1.00 43.58  ? 298 ILE B CA    1 
ATOM   6375  C C     . ILE B 1 298 ? -21.504 35.810  -18.908  1.00 44.91  ? 298 ILE B C     1 
ATOM   6376  O O     . ILE B 1 298 ? -22.229 34.898  -19.264  1.00 47.63  ? 298 ILE B O     1 
ATOM   6377  C CB    . ILE B 1 298 ? -19.705 36.327  -20.598  1.00 45.85  ? 298 ILE B CB    1 
ATOM   6378  C CG1   . ILE B 1 298 ? -20.479 35.653  -21.731  1.00 40.57  ? 298 ILE B CG1   1 
ATOM   6379  C CG2   . ILE B 1 298 ? -18.208 36.260  -20.828  1.00 46.12  ? 298 ILE B CG2   1 
ATOM   6380  C CD1   . ILE B 1 298 ? -20.201 36.228  -23.087  1.00 41.33  ? 298 ILE B CD1   1 
ATOM   6381  N N     . PRO B 1 299 ? -21.975 36.872  -18.222  1.00 50.28  ? 299 PRO B N     1 
ATOM   6382  C CA    . PRO B 1 299 ? -23.400 37.079  -18.013  1.00 47.88  ? 299 PRO B CA    1 
ATOM   6383  C C     . PRO B 1 299 ? -24.059 37.706  -19.228  1.00 47.11  ? 299 PRO B C     1 
ATOM   6384  O O     . PRO B 1 299 ? -23.389 38.208  -20.112  1.00 44.22  ? 299 PRO B O     1 
ATOM   6385  C CB    . PRO B 1 299 ? -23.423 38.020  -16.805  1.00 53.95  ? 299 PRO B CB    1 
ATOM   6386  C CG    . PRO B 1 299 ? -22.192 38.834  -16.986  1.00 56.58  ? 299 PRO B CG    1 
ATOM   6387  C CD    . PRO B 1 299 ? -21.160 37.851  -17.499  1.00 53.92  ? 299 PRO B CD    1 
ATOM   6388  N N     . PRO B 1 300 ? -25.398 37.622  -19.342  1.00 59.67  ? 300 PRO B N     1 
ATOM   6389  C CA    . PRO B 1 300 ? -26.087 38.139  -20.524  1.00 59.23  ? 300 PRO B CA    1 
ATOM   6390  C C     . PRO B 1 300 ? -25.762 39.601  -20.830  1.00 52.07  ? 300 PRO B C     1 
ATOM   6391  O O     . PRO B 1 300 ? -25.665 39.977  -21.992  1.00 50.16  ? 300 PRO B O     1 
ATOM   6392  C CB    . PRO B 1 300 ? -27.582 37.912  -20.205  1.00 59.17  ? 300 PRO B CB    1 
ATOM   6393  C CG    . PRO B 1 300 ? -27.575 36.735  -19.223  1.00 61.42  ? 300 PRO B CG    1 
ATOM   6394  C CD    . PRO B 1 300 ? -26.297 36.897  -18.418  1.00 58.18  ? 300 PRO B CD    1 
ATOM   6395  N N     . SER B 1 301 ? -25.601 40.425  -19.797  1.00 47.97  ? 301 SER B N     1 
ATOM   6396  C CA    . SER B 1 301 ? -25.376 41.847  -20.000  1.00 49.37  ? 301 SER B CA    1 
ATOM   6397  C C     . SER B 1 301 ? -24.069 42.105  -20.748  1.00 42.02  ? 301 SER B C     1 
ATOM   6398  O O     . SER B 1 301 ? -24.008 43.000  -21.583  1.00 50.79  ? 301 SER B O     1 
ATOM   6399  C CB    . SER B 1 301 ? -25.393 42.589  -18.686  1.00 53.77  ? 301 SER B CB    1 
ATOM   6400  O OG    . SER B 1 301 ? -24.382 42.088  -17.833  1.00 64.27  ? 301 SER B OG    1 
ATOM   6401  N N     . VAL B 1 302 ? -23.017 41.336  -20.454  1.00 41.94  ? 302 VAL B N     1 
ATOM   6402  C CA    . VAL B 1 302 ? -21.755 41.457  -21.177  1.00 43.25  ? 302 VAL B CA    1 
ATOM   6403  C C     . VAL B 1 302 ? -21.966 41.069  -22.638  1.00 49.88  ? 302 VAL B C     1 
ATOM   6404  O O     . VAL B 1 302 ? -21.360 41.663  -23.532  1.00 48.07  ? 302 VAL B O     1 
ATOM   6405  C CB    . VAL B 1 302 ? -20.637 40.610  -20.546  1.00 45.63  ? 302 VAL B CB    1 
ATOM   6406  C CG1   . VAL B 1 302 ? -19.428 40.474  -21.452  1.00 48.73  ? 302 VAL B CG1   1 
ATOM   6407  C CG2   . VAL B 1 302 ? -20.209 41.151  -19.200  1.00 48.34  ? 302 VAL B CG2   1 
ATOM   6408  N N     . ALA B 1 303 ? -22.820 40.056  -22.861  1.00 48.15  ? 303 ALA B N     1 
ATOM   6409  C CA    . ALA B 1 303 ? -23.033 39.519  -24.192  1.00 48.01  ? 303 ALA B CA    1 
ATOM   6410  C C     . ALA B 1 303 ? -23.658 40.589  -25.092  1.00 47.99  ? 303 ALA B C     1 
ATOM   6411  O O     . ALA B 1 303 ? -23.198 40.779  -26.230  1.00 37.41  ? 303 ALA B O     1 
ATOM   6412  C CB    . ALA B 1 303 ? -23.862 38.263  -24.106  1.00 43.64  ? 303 ALA B CB    1 
ATOM   6413  N N     . LYS B 1 304 ? -24.676 41.284  -24.549  1.00 43.84  ? 304 LYS B N     1 
ATOM   6414  C CA    . LYS B 1 304 ? -25.368 42.361  -25.243  1.00 51.83  ? 304 LYS B CA    1 
ATOM   6415  C C     . LYS B 1 304 ? -24.374 43.426  -25.696  1.00 48.40  ? 304 LYS B C     1 
ATOM   6416  O O     . LYS B 1 304 ? -24.527 44.016  -26.747  1.00 54.09  ? 304 LYS B O     1 
ATOM   6417  C CB    . LYS B 1 304 ? -26.437 42.970  -24.330  1.00 56.45  ? 304 LYS B CB    1 
ATOM   6418  C CG    . LYS B 1 304 ? -27.693 42.117  -24.180  1.00 67.34  ? 304 LYS B CG    1 
ATOM   6419  C CD    . LYS B 1 304 ? -28.369 42.235  -22.833  1.00 85.72  ? 304 LYS B CD    1 
ATOM   6420  C CE    . LYS B 1 304 ? -29.230 43.466  -22.684  1.00 93.62  ? 304 LYS B CE    1 
ATOM   6421  N NZ    . LYS B 1 304 ? -30.542 43.241  -23.323  1.00 100.15 ? 304 LYS B NZ    1 
ATOM   6422  N N     . THR B 1 305 ? -23.340 43.606  -24.888  1.00 49.00  ? 305 THR B N     1 
ATOM   6423  C CA    . THR B 1 305 ? -22.335 44.632  -25.032  1.00 49.60  ? 305 THR B CA    1 
ATOM   6424  C C     . THR B 1 305 ? -21.302 44.202  -26.062  1.00 46.42  ? 305 THR B C     1 
ATOM   6425  O O     . THR B 1 305 ? -20.829 45.029  -26.843  1.00 43.74  ? 305 THR B O     1 
ATOM   6426  C CB    . THR B 1 305 ? -21.745 44.915  -23.636  1.00 55.52  ? 305 THR B CB    1 
ATOM   6427  O OG1   . THR B 1 305 ? -22.536 45.958  -23.050  1.00 62.73  ? 305 THR B OG1   1 
ATOM   6428  C CG2   . THR B 1 305 ? -20.278 45.284  -23.651  1.00 50.31  ? 305 THR B CG2   1 
ATOM   6429  N N     . MET B 1 306 ? -20.928 42.914  -26.039  1.00 46.95  ? 306 MET B N     1 
ATOM   6430  C CA    . MET B 1 306 ? -20.051 42.372  -27.069  1.00 47.80  ? 306 MET B CA    1 
ATOM   6431  C C     . MET B 1 306 ? -20.707 42.494  -28.454  1.00 45.22  ? 306 MET B C     1 
ATOM   6432  O O     . MET B 1 306 ? -20.024 42.806  -29.425  1.00 51.58  ? 306 MET B O     1 
ATOM   6433  C CB    . MET B 1 306 ? -19.714 40.914  -26.779  1.00 49.65  ? 306 MET B CB    1 
ATOM   6434  C CG    . MET B 1 306 ? -18.759 40.756  -25.631  1.00 54.63  ? 306 MET B CG    1 
ATOM   6435  S SD    . MET B 1 306 ? -18.490 39.020  -25.197  1.00 53.03  ? 306 MET B SD    1 
ATOM   6436  C CE    . MET B 1 306 ? -17.236 38.635  -26.406  1.00 60.76  ? 306 MET B CE    1 
ATOM   6437  N N     . MET B 1 307 ? -22.037 42.331  -28.508  1.00 43.08  ? 307 MET B N     1 
ATOM   6438  C CA    . MET B 1 307 ? -22.828 42.355  -29.733  1.00 48.44  ? 307 MET B CA    1 
ATOM   6439  C C     . MET B 1 307 ? -22.883 43.751  -30.342  1.00 47.14  ? 307 MET B C     1 
ATOM   6440  O O     . MET B 1 307 ? -22.778 43.875  -31.558  1.00 43.29  ? 307 MET B O     1 
ATOM   6441  C CB    . MET B 1 307 ? -24.268 41.896  -29.464  1.00 51.64  ? 307 MET B CB    1 
ATOM   6442  C CG    . MET B 1 307 ? -24.365 40.380  -29.240  1.00 57.62  ? 307 MET B CG    1 
ATOM   6443  S SD    . MET B 1 307 ? -25.897 39.889  -28.421  1.00 53.20  ? 307 MET B SD    1 
ATOM   6444  C CE    . MET B 1 307 ? -27.063 40.360  -29.698  1.00 46.86  ? 307 MET B CE    1 
ATOM   6445  N N     . ALA B 1 308 ? -23.072 44.784  -29.503  1.00 49.49  ? 308 ALA B N     1 
ATOM   6446  C CA    . ALA B 1 308 ? -23.111 46.160  -29.986  1.00 46.22  ? 308 ALA B CA    1 
ATOM   6447  C C     . ALA B 1 308 ? -21.703 46.563  -30.400  1.00 43.12  ? 308 ALA B C     1 
ATOM   6448  O O     . ALA B 1 308 ? -21.500 47.108  -31.464  1.00 40.31  ? 308 ALA B O     1 
ATOM   6449  C CB    . ALA B 1 308 ? -23.692 47.088  -28.954  1.00 45.13  ? 308 ALA B CB    1 
ATOM   6450  N N     . ASP B 1 309 ? -20.701 46.197  -29.611  1.00 41.95  ? 309 ASP B N     1 
ATOM   6451  C CA    . ASP B 1 309 ? -19.357 46.612  -29.983  1.00 51.33  ? 309 ASP B CA    1 
ATOM   6452  C C     . ASP B 1 309 ? -18.955 46.016  -31.330  1.00 55.73  ? 309 ASP B C     1 
ATOM   6453  O O     . ASP B 1 309 ? -18.275 46.672  -32.116  1.00 54.04  ? 309 ASP B O     1 
ATOM   6454  C CB    . ASP B 1 309 ? -18.307 46.219  -28.942  1.00 51.54  ? 309 ASP B CB    1 
ATOM   6455  C CG    . ASP B 1 309 ? -18.335 47.029  -27.653  1.00 58.25  ? 309 ASP B CG    1 
ATOM   6456  O OD1   . ASP B 1 309 ? -19.263 47.875  -27.490  1.00 51.68  ? 309 ASP B OD1   1 
ATOM   6457  O OD2   . ASP B 1 309 ? -17.411 46.808  -26.818  1.00 57.13  ? 309 ASP B OD2   1 
ATOM   6458  N N     . LEU B 1 310 ? -19.287 44.736  -31.547  1.00 58.12  ? 310 LEU B N     1 
ATOM   6459  C CA    . LEU B 1 310 ? -18.612 43.963  -32.579  1.00 54.81  ? 310 LEU B CA    1 
ATOM   6460  C C     . LEU B 1 310 ? -19.514 43.780  -33.803  1.00 47.77  ? 310 LEU B C     1 
ATOM   6461  O O     . LEU B 1 310 ? -19.072 43.186  -34.767  1.00 39.01  ? 310 LEU B O     1 
ATOM   6462  C CB    . LEU B 1 310 ? -18.171 42.611  -31.998  1.00 56.29  ? 310 LEU B CB    1 
ATOM   6463  C CG    . LEU B 1 310 ? -17.156 42.674  -30.855  1.00 62.41  ? 310 LEU B CG    1 
ATOM   6464  C CD1   . LEU B 1 310 ? -16.736 41.274  -30.423  1.00 56.42  ? 310 LEU B CD1   1 
ATOM   6465  C CD2   . LEU B 1 310 ? -15.926 43.492  -31.258  1.00 66.80  ? 310 LEU B CD2   1 
ATOM   6466  N N     . ASP B 1 311 ? -20.764 44.271  -33.747  1.00 47.53  ? 311 ASP B N     1 
ATOM   6467  C CA    . ASP B 1 311 ? -21.774 44.016  -34.763  1.00 48.18  ? 311 ASP B CA    1 
ATOM   6468  C C     . ASP B 1 311 ? -21.838 42.513  -35.073  1.00 51.56  ? 311 ASP B C     1 
ATOM   6469  O O     . ASP B 1 311 ? -21.620 42.103  -36.212  1.00 49.79  ? 311 ASP B O     1 
ATOM   6470  C CB    . ASP B 1 311 ? -21.505 44.898  -35.992  1.00 54.42  ? 311 ASP B CB    1 
ATOM   6471  C CG    . ASP B 1 311 ? -21.739 46.401  -35.818  1.00 58.28  ? 311 ASP B CG    1 
ATOM   6472  O OD1   . ASP B 1 311 ? -22.132 46.863  -34.688  1.00 57.52  ? 311 ASP B OD1   1 
ATOM   6473  O OD2   . ASP B 1 311 ? -21.548 47.118  -36.823  1.00 57.91  ? 311 ASP B OD2   1 
ATOM   6474  N N     . LEU B 1 312 ? -22.051 41.700  -34.021  1.00 53.29  ? 312 LEU B N     1 
ATOM   6475  C CA    . LEU B 1 312 ? -22.354 40.272  -34.091  1.00 43.61  ? 312 LEU B CA    1 
ATOM   6476  C C     . LEU B 1 312 ? -23.674 40.015  -33.365  1.00 40.05  ? 312 LEU B C     1 
ATOM   6477  O O     . LEU B 1 312 ? -24.016 40.723  -32.425  1.00 40.82  ? 312 LEU B O     1 
ATOM   6478  C CB    . LEU B 1 312 ? -21.271 39.460  -33.381  1.00 41.30  ? 312 LEU B CB    1 
ATOM   6479  C CG    . LEU B 1 312 ? -19.862 39.558  -33.936  1.00 45.00  ? 312 LEU B CG    1 
ATOM   6480  C CD1   . LEU B 1 312 ? -18.895 38.784  -33.052  1.00 46.68  ? 312 LEU B CD1   1 
ATOM   6481  C CD2   . LEU B 1 312 ? -19.812 39.036  -35.358  1.00 48.57  ? 312 LEU B CD2   1 
ATOM   6482  N N     . GLY B 1 313 ? -24.374 38.949  -33.751  1.00 43.41  ? 313 GLY B N     1 
ATOM   6483  C CA    . GLY B 1 313 ? -25.542 38.480  -33.018  1.00 46.26  ? 313 GLY B CA    1 
ATOM   6484  C C     . GLY B 1 313 ? -25.206 37.367  -32.025  1.00 41.12  ? 313 GLY B C     1 
ATOM   6485  O O     . GLY B 1 313 ? -24.041 36.997  -31.868  1.00 40.39  ? 313 GLY B O     1 
ATOM   6486  N N     . MET B 1 314 ? -26.248 36.830  -31.374  1.00 40.29  ? 314 MET B N     1 
ATOM   6487  C CA    . MET B 1 314 ? -26.130 35.579  -30.624  1.00 45.48  ? 314 MET B CA    1 
ATOM   6488  C C     . MET B 1 314 ? -25.802 34.390  -31.544  1.00 38.57  ? 314 MET B C     1 
ATOM   6489  O O     . MET B 1 314 ? -25.095 33.460  -31.161  1.00 40.24  ? 314 MET B O     1 
ATOM   6490  C CB    . MET B 1 314 ? -27.423 35.310  -29.856  1.00 45.89  ? 314 MET B CB    1 
ATOM   6491  C CG    . MET B 1 314 ? -27.567 36.219  -28.648  1.00 49.28  ? 314 MET B CG    1 
ATOM   6492  S SD    . MET B 1 314 ? -26.274 35.909  -27.399  1.00 52.10  ? 314 MET B SD    1 
ATOM   6493  C CE    . MET B 1 314 ? -26.587 34.202  -26.942  1.00 51.56  ? 314 MET B CE    1 
ATOM   6494  N N     . TRP B 1 315 ? -26.291 34.428  -32.774  1.00 38.72  ? 315 TRP B N     1 
ATOM   6495  C CA    . TRP B 1 315 ? -25.945 33.453  -33.799  1.00 39.38  ? 315 TRP B CA    1 
ATOM   6496  C C     . TRP B 1 315 ? -25.470 34.211  -35.036  1.00 41.54  ? 315 TRP B C     1 
ATOM   6497  O O     . TRP B 1 315 ? -26.114 35.191  -35.420  1.00 46.59  ? 315 TRP B O     1 
ATOM   6498  C CB    . TRP B 1 315 ? -27.183 32.589  -34.128  1.00 37.50  ? 315 TRP B CB    1 
ATOM   6499  C CG    . TRP B 1 315 ? -27.571 31.696  -33.009  1.00 33.42  ? 315 TRP B CG    1 
ATOM   6500  C CD1   . TRP B 1 315 ? -28.594 31.851  -32.128  1.00 35.66  ? 315 TRP B CD1   1 
ATOM   6501  C CD2   . TRP B 1 315 ? -26.841 30.544  -32.583  1.00 34.33  ? 315 TRP B CD2   1 
ATOM   6502  N NE1   . TRP B 1 315 ? -28.511 30.896  -31.147  1.00 37.47  ? 315 TRP B NE1   1 
ATOM   6503  C CE2   . TRP B 1 315 ? -27.477 30.057  -31.428  1.00 33.25  ? 315 TRP B CE2   1 
ATOM   6504  C CE3   . TRP B 1 315 ? -25.658 29.949  -33.009  1.00 31.41  ? 315 TRP B CE3   1 
ATOM   6505  C CZ2   . TRP B 1 315 ? -27.020 28.945  -30.738  1.00 38.07  ? 315 TRP B CZ2   1 
ATOM   6506  C CZ3   . TRP B 1 315 ? -25.220 28.830  -32.341  1.00 36.75  ? 315 TRP B CZ3   1 
ATOM   6507  C CH2   . TRP B 1 315 ? -25.895 28.329  -31.226  1.00 36.13  ? 315 TRP B CH2   1 
ATOM   6508  N N     . ASN B 1 316 ? -24.434 33.685  -35.708  1.00 41.62  ? 316 ASN B N     1 
ATOM   6509  C CA    . ASN B 1 316 ? -23.757 34.394  -36.793  1.00 42.35  ? 316 ASN B CA    1 
ATOM   6510  C C     . ASN B 1 316 ? -23.517 33.478  -38.005  1.00 43.24  ? 316 ASN B C     1 
ATOM   6511  O O     . ASN B 1 316 ? -22.572 32.676  -38.048  1.00 38.00  ? 316 ASN B O     1 
ATOM   6512  C CB    . ASN B 1 316 ? -22.442 35.003  -36.283  1.00 40.01  ? 316 ASN B CB    1 
ATOM   6513  C CG    . ASN B 1 316 ? -22.665 36.008  -35.167  1.00 42.71  ? 316 ASN B CG    1 
ATOM   6514  O OD1   . ASN B 1 316 ? -23.097 37.129  -35.416  1.00 48.26  ? 316 ASN B OD1   1 
ATOM   6515  N ND2   . ASN B 1 316 ? -22.434 35.609  -33.929  1.00 43.26  ? 316 ASN B ND2   1 
ATOM   6516  N N     . PHE B 1 317 ? -24.329 33.702  -39.045  1.00 39.85  ? 317 PHE B N     1 
ATOM   6517  C CA    . PHE B 1 317 ? -24.323 32.875  -40.231  1.00 40.07  ? 317 PHE B CA    1 
ATOM   6518  C C     . PHE B 1 317 ? -23.367 33.453  -41.264  1.00 43.69  ? 317 PHE B C     1 
ATOM   6519  O O     . PHE B 1 317 ? -23.700 34.443  -41.930  1.00 42.72  ? 317 PHE B O     1 
ATOM   6520  C CB    . PHE B 1 317 ? -25.749 32.797  -40.783  1.00 46.79  ? 317 PHE B CB    1 
ATOM   6521  C CG    . PHE B 1 317 ? -25.898 32.044  -42.084  1.00 45.45  ? 317 PHE B CG    1 
ATOM   6522  C CD1   . PHE B 1 317 ? -24.955 31.117  -42.496  1.00 49.20  ? 317 PHE B CD1   1 
ATOM   6523  C CD2   . PHE B 1 317 ? -26.989 32.269  -42.902  1.00 41.44  ? 317 PHE B CD2   1 
ATOM   6524  C CE1   . PHE B 1 317 ? -25.099 30.451  -43.702  1.00 50.42  ? 317 PHE B CE1   1 
ATOM   6525  C CE2   . PHE B 1 317 ? -27.112 31.626  -44.120  1.00 41.17  ? 317 PHE B CE2   1 
ATOM   6526  C CZ    . PHE B 1 317 ? -26.159 30.731  -44.525  1.00 42.45  ? 317 PHE B CZ    1 
ATOM   6527  N N     . CYS B 1 318 ? -22.212 32.794  -41.426  1.00 46.34  ? 318 CYS B N     1 
ATOM   6528  C CA    . CYS B 1 318 ? -21.223 33.211  -42.408  1.00 52.98  ? 318 CYS B CA    1 
ATOM   6529  C C     . CYS B 1 318 ? -21.200 32.218  -43.583  1.00 57.96  ? 318 CYS B C     1 
ATOM   6530  O O     . CYS B 1 318 ? -21.131 31.004  -43.403  1.00 55.68  ? 318 CYS B O     1 
ATOM   6531  C CB    . CYS B 1 318 ? -19.859 33.438  -41.753  1.00 52.62  ? 318 CYS B CB    1 
ATOM   6532  S SG    . CYS B 1 318 ? -19.144 31.976  -40.961  1.00 53.50  ? 318 CYS B SG    1 
ATOM   6533  N N     . GLY B 1 319 ? -21.313 32.761  -44.805  1.00 59.79  ? 319 GLY B N     1 
ATOM   6534  C CA    . GLY B 1 319 ? -21.426 31.974  -46.019  1.00 55.34  ? 319 GLY B CA    1 
ATOM   6535  C C     . GLY B 1 319 ? -20.888 32.730  -47.225  1.00 52.50  ? 319 GLY B C     1 
ATOM   6536  O O     . GLY B 1 319 ? -20.280 33.791  -47.084  1.00 46.36  ? 319 GLY B O     1 
ATOM   6537  N N     . ALA B 1 320 ? -21.110 32.175  -48.419  1.00 50.08  ? 320 ALA B N     1 
ATOM   6538  C CA    . ALA B 1 320 ? -20.522 32.766  -49.606  1.00 48.55  ? 320 ALA B CA    1 
ATOM   6539  C C     . ALA B 1 320 ? -21.229 32.289  -50.863  1.00 45.19  ? 320 ALA B C     1 
ATOM   6540  O O     . ALA B 1 320 ? -21.396 31.101  -51.067  1.00 43.98  ? 320 ALA B O     1 
ATOM   6541  C CB    . ALA B 1 320 ? -19.044 32.430  -49.678  1.00 47.40  ? 320 ALA B CB    1 
ATOM   6542  N N     . LEU B 1 321 ? -21.526 33.241  -51.737  1.00 47.32  ? 321 LEU B N     1 
ATOM   6543  C CA    . LEU B 1 321 ? -21.957 32.962  -53.096  1.00 50.44  ? 321 LEU B CA    1 
ATOM   6544  C C     . LEU B 1 321 ? -20.740 32.756  -53.993  1.00 53.56  ? 321 LEU B C     1 
ATOM   6545  O O     . LEU B 1 321 ? -19.696 33.369  -53.784  1.00 56.53  ? 321 LEU B O     1 
ATOM   6546  C CB    . LEU B 1 321 ? -22.800 34.149  -53.535  1.00 48.22  ? 321 LEU B CB    1 
ATOM   6547  C CG    . LEU B 1 321 ? -23.814 34.556  -52.465  1.00 50.07  ? 321 LEU B CG    1 
ATOM   6548  C CD1   . LEU B 1 321 ? -24.555 35.825  -52.853  1.00 51.24  ? 321 LEU B CD1   1 
ATOM   6549  C CD2   . LEU B 1 321 ? -24.782 33.412  -52.181  1.00 48.73  ? 321 LEU B CD2   1 
ATOM   6550  N N     . TYR B 1 322 ? -20.865 31.852  -54.967  1.00 53.35  ? 322 TYR B N     1 
ATOM   6551  C CA    . TYR B 1 322 ? -19.803 31.601  -55.935  1.00 52.48  ? 322 TYR B CA    1 
ATOM   6552  C C     . TYR B 1 322 ? -20.417 31.623  -57.332  1.00 52.71  ? 322 TYR B C     1 
ATOM   6553  O O     . TYR B 1 322 ? -21.591 31.328  -57.484  1.00 66.01  ? 322 TYR B O     1 
ATOM   6554  C CB    . TYR B 1 322 ? -19.120 30.257  -55.673  1.00 54.09  ? 322 TYR B CB    1 
ATOM   6555  C CG    . TYR B 1 322 ? -18.606 30.045  -54.266  1.00 53.00  ? 322 TYR B CG    1 
ATOM   6556  C CD1   . TYR B 1 322 ? -19.472 29.810  -53.207  1.00 48.13  ? 322 TYR B CD1   1 
ATOM   6557  C CD2   . TYR B 1 322 ? -17.240 30.082  -53.997  1.00 50.76  ? 322 TYR B CD2   1 
ATOM   6558  C CE1   . TYR B 1 322 ? -18.998 29.623  -51.917  1.00 48.09  ? 322 TYR B CE1   1 
ATOM   6559  C CE2   . TYR B 1 322 ? -16.750 29.862  -52.726  1.00 45.70  ? 322 TYR B CE2   1 
ATOM   6560  C CZ    . TYR B 1 322 ? -17.635 29.648  -51.680  1.00 48.24  ? 322 TYR B CZ    1 
ATOM   6561  O OH    . TYR B 1 322 ? -17.138 29.452  -50.413  1.00 51.36  ? 322 TYR B OH    1 
ATOM   6562  N N     . GLY B 1 323 ? -19.656 32.038  -58.337  1.00 52.84  ? 323 GLY B N     1 
ATOM   6563  C CA    . GLY B 1 323 ? -20.114 31.973  -59.718  1.00 58.09  ? 323 GLY B CA    1 
ATOM   6564  C C     . GLY B 1 323 ? -20.397 33.347  -60.315  1.00 59.32  ? 323 GLY B C     1 
ATOM   6565  O O     . GLY B 1 323 ? -20.145 34.365  -59.677  1.00 64.88  ? 323 GLY B O     1 
ATOM   6566  N N     . PRO B 1 324 ? -20.895 33.413  -61.574  1.00 74.64  ? 324 PRO B N     1 
ATOM   6567  C CA    . PRO B 1 324 ? -21.085 34.686  -62.269  1.00 69.81  ? 324 PRO B CA    1 
ATOM   6568  C C     . PRO B 1 324 ? -22.082 35.544  -61.500  1.00 68.53  ? 324 PRO B C     1 
ATOM   6569  O O     . PRO B 1 324 ? -23.007 34.998  -60.895  1.00 58.33  ? 324 PRO B O     1 
ATOM   6570  C CB    . PRO B 1 324 ? -21.667 34.314  -63.642  1.00 65.64  ? 324 PRO B CB    1 
ATOM   6571  C CG    . PRO B 1 324 ? -21.396 32.838  -63.807  1.00 66.49  ? 324 PRO B CG    1 
ATOM   6572  C CD    . PRO B 1 324 ? -21.303 32.264  -62.405  1.00 74.80  ? 324 PRO B CD    1 
ATOM   6573  N N     . PRO B 1 325 ? -21.913 36.891  -61.507  1.00 66.33  ? 325 PRO B N     1 
ATOM   6574  C CA    . PRO B 1 325 ? -22.843 37.815  -60.838  1.00 60.04  ? 325 PRO B CA    1 
ATOM   6575  C C     . PRO B 1 325 ? -24.340 37.590  -61.015  1.00 60.99  ? 325 PRO B C     1 
ATOM   6576  O O     . PRO B 1 325 ? -25.069 37.606  -60.034  1.00 64.15  ? 325 PRO B O     1 
ATOM   6577  C CB    . PRO B 1 325 ? -22.400 39.168  -61.387  1.00 60.35  ? 325 PRO B CB    1 
ATOM   6578  C CG    . PRO B 1 325 ? -20.877 38.982  -61.463  1.00 65.93  ? 325 PRO B CG    1 
ATOM   6579  C CD    . PRO B 1 325 ? -20.731 37.586  -62.046  1.00 63.42  ? 325 PRO B CD    1 
ATOM   6580  N N     . PRO B 1 326 ? -24.874 37.372  -62.237  1.00 73.87  ? 326 PRO B N     1 
ATOM   6581  C CA    . PRO B 1 326 ? -26.294 37.011  -62.388  1.00 66.88  ? 326 PRO B CA    1 
ATOM   6582  C C     . PRO B 1 326 ? -26.752 35.794  -61.573  1.00 71.79  ? 326 PRO B C     1 
ATOM   6583  O O     . PRO B 1 326 ? -27.916 35.747  -61.156  1.00 62.08  ? 326 PRO B O     1 
ATOM   6584  C CB    . PRO B 1 326 ? -26.411 36.714  -63.894  1.00 57.57  ? 326 PRO B CB    1 
ATOM   6585  C CG    . PRO B 1 326 ? -25.323 37.578  -64.507  1.00 62.47  ? 326 PRO B CG    1 
ATOM   6586  C CD    . PRO B 1 326 ? -24.176 37.516  -63.526  1.00 64.71  ? 326 PRO B CD    1 
ATOM   6587  N N     . VAL B 1 327 ? -25.835 34.817  -61.374  1.00 69.86  ? 327 VAL B N     1 
ATOM   6588  C CA    . VAL B 1 327 ? -26.095 33.619  -60.584  1.00 68.79  ? 327 VAL B CA    1 
ATOM   6589  C C     . VAL B 1 327 ? -26.118 34.010  -59.108  1.00 63.96  ? 327 VAL B C     1 
ATOM   6590  O O     . VAL B 1 327 ? -27.131 33.836  -58.435  1.00 57.24  ? 327 VAL B O     1 
ATOM   6591  C CB    . VAL B 1 327 ? -25.051 32.511  -60.834  1.00 69.83  ? 327 VAL B CB    1 
ATOM   6592  C CG1   . VAL B 1 327 ? -25.387 31.228  -60.087  1.00 69.60  ? 327 VAL B CG1   1 
ATOM   6593  C CG2   . VAL B 1 327 ? -24.887 32.217  -62.314  1.00 74.78  ? 327 VAL B CG2   1 
ATOM   6594  N N     . MET B 1 328 ? -25.001 34.585  -58.647  1.00 53.87  ? 328 MET B N     1 
ATOM   6595  C CA    . MET B 1 328 ? -24.854 35.076  -57.287  1.00 57.78  ? 328 MET B CA    1 
ATOM   6596  C C     . MET B 1 328 ? -26.068 35.914  -56.871  1.00 57.76  ? 328 MET B C     1 
ATOM   6597  O O     . MET B 1 328 ? -26.593 35.683  -55.795  1.00 56.19  ? 328 MET B O     1 
ATOM   6598  C CB    . MET B 1 328 ? -23.546 35.872  -57.121  1.00 56.95  ? 328 MET B CB    1 
ATOM   6599  C CG    . MET B 1 328 ? -22.315 34.965  -56.976  1.00 57.53  ? 328 MET B CG    1 
ATOM   6600  S SD    . MET B 1 328 ? -20.683 35.740  -56.684  1.00 64.61  ? 328 MET B SD    1 
ATOM   6601  C CE    . MET B 1 328 ? -20.722 37.164  -57.773  1.00 66.99  ? 328 MET B CE    1 
ATOM   6602  N N     . ASP B 1 329 ? -26.533 36.840  -57.725  1.00 62.52  ? 329 ASP B N     1 
ATOM   6603  C CA    . ASP B 1 329 ? -27.713 37.656  -57.449  1.00 66.03  ? 329 ASP B CA    1 
ATOM   6604  C C     . ASP B 1 329 ? -28.917 36.801  -57.095  1.00 60.22  ? 329 ASP B C     1 
ATOM   6605  O O     . ASP B 1 329 ? -29.644 37.119  -56.164  1.00 69.73  ? 329 ASP B O     1 
ATOM   6606  C CB    . ASP B 1 329 ? -28.203 38.480  -58.647  1.00 70.57  ? 329 ASP B CB    1 
ATOM   6607  C CG    . ASP B 1 329 ? -27.398 39.733  -58.928  1.00 77.09  ? 329 ASP B CG    1 
ATOM   6608  O OD1   . ASP B 1 329 ? -26.421 39.978  -58.185  1.00 84.01  ? 329 ASP B OD1   1 
ATOM   6609  O OD2   . ASP B 1 329 ? -27.746 40.444  -59.895  1.00 78.42  ? 329 ASP B OD2   1 
ATOM   6610  N N     . THR B 1 330 ? -29.144 35.766  -57.898  1.00 59.79  ? 330 THR B N     1 
ATOM   6611  C CA    . THR B 1 330 ? -30.357 34.964  -57.829  1.00 64.33  ? 330 THR B CA    1 
ATOM   6612  C C     . THR B 1 330 ? -30.371 34.096  -56.573  1.00 59.16  ? 330 THR B C     1 
ATOM   6613  O O     . THR B 1 330 ? -31.406 34.023  -55.908  1.00 60.57  ? 330 THR B O     1 
ATOM   6614  C CB    . THR B 1 330 ? -30.481 34.085  -59.081  1.00 67.37  ? 330 THR B CB    1 
ATOM   6615  O OG1   . THR B 1 330 ? -30.702 34.955  -60.192  1.00 62.51  ? 330 THR B OG1   1 
ATOM   6616  C CG2   . THR B 1 330 ? -31.589 33.061  -58.985  1.00 69.78  ? 330 THR B CG2   1 
ATOM   6617  N N     . LEU B 1 331 ? -29.234 33.416  -56.317  1.00 50.58  ? 331 LEU B N     1 
ATOM   6618  C CA    . LEU B 1 331 ? -28.959 32.747  -55.058  1.00 52.55  ? 331 LEU B CA    1 
ATOM   6619  C C     . LEU B 1 331 ? -29.185 33.736  -53.911  1.00 54.39  ? 331 LEU B C     1 
ATOM   6620  O O     . LEU B 1 331 ? -30.027 33.495  -53.068  1.00 54.77  ? 331 LEU B O     1 
ATOM   6621  C CB    . LEU B 1 331 ? -27.524 32.200  -55.064  1.00 53.24  ? 331 LEU B CB    1 
ATOM   6622  C CG    . LEU B 1 331 ? -27.210 31.153  -56.139  1.00 55.81  ? 331 LEU B CG    1 
ATOM   6623  C CD1   . LEU B 1 331 ? -25.846 30.508  -55.925  1.00 57.06  ? 331 LEU B CD1   1 
ATOM   6624  C CD2   . LEU B 1 331 ? -28.274 30.075  -56.210  1.00 55.36  ? 331 LEU B CD2   1 
ATOM   6625  N N     . TRP B 1 332 ? -28.536 34.908  -53.938  1.00 56.29  ? 332 TRP B N     1 
ATOM   6626  C CA    . TRP B 1 332 ? -28.669 35.871  -52.853  1.00 55.92  ? 332 TRP B CA    1 
ATOM   6627  C C     . TRP B 1 332 ? -30.134 36.210  -52.562  1.00 56.78  ? 332 TRP B C     1 
ATOM   6628  O O     . TRP B 1 332 ? -30.518 36.366  -51.399  1.00 62.12  ? 332 TRP B O     1 
ATOM   6629  C CB    . TRP B 1 332 ? -27.868 37.153  -53.082  1.00 48.03  ? 332 TRP B CB    1 
ATOM   6630  C CG    . TRP B 1 332 ? -27.995 38.081  -51.912  1.00 57.79  ? 332 TRP B CG    1 
ATOM   6631  C CD1   . TRP B 1 332 ? -28.567 39.318  -51.903  1.00 57.87  ? 332 TRP B CD1   1 
ATOM   6632  C CD2   . TRP B 1 332 ? -27.665 37.787  -50.535  1.00 64.75  ? 332 TRP B CD2   1 
ATOM   6633  N NE1   . TRP B 1 332 ? -28.559 39.842  -50.638  1.00 63.69  ? 332 TRP B NE1   1 
ATOM   6634  C CE2   . TRP B 1 332 ? -28.000 38.934  -49.776  1.00 66.80  ? 332 TRP B CE2   1 
ATOM   6635  C CE3   . TRP B 1 332 ? -27.100 36.687  -49.873  1.00 53.56  ? 332 TRP B CE3   1 
ATOM   6636  C CZ2   . TRP B 1 332 ? -27.765 39.013  -48.401  1.00 61.68  ? 332 TRP B CZ2   1 
ATOM   6637  C CZ3   . TRP B 1 332 ? -26.869 36.761  -48.513  1.00 55.19  ? 332 TRP B CZ3   1 
ATOM   6638  C CH2   . TRP B 1 332 ? -27.210 37.907  -47.788  1.00 63.53  ? 332 TRP B CH2   1 
ATOM   6639  N N     . THR B 1 333 ? -30.949 36.334  -53.611  1.00 56.15  ? 333 THR B N     1 
ATOM   6640  C CA    . THR B 1 333 ? -32.344 36.713  -53.445  1.00 54.45  ? 333 THR B CA    1 
ATOM   6641  C C     . THR B 1 333 ? -33.044 35.643  -52.611  1.00 51.40  ? 333 THR B C     1 
ATOM   6642  O O     . THR B 1 333 ? -33.756 35.978  -51.664  1.00 53.93  ? 333 THR B O     1 
ATOM   6643  C CB    . THR B 1 333 ? -32.988 37.007  -54.810  1.00 56.71  ? 333 THR B CB    1 
ATOM   6644  O OG1   . THR B 1 333 ? -32.369 38.194  -55.324  1.00 61.32  ? 333 THR B OG1   1 
ATOM   6645  C CG2   . THR B 1 333 ? -34.489 37.196  -54.748  1.00 48.09  ? 333 THR B CG2   1 
ATOM   6646  N N     . ALA B 1 334 ? -32.760 34.361  -52.910  1.00 45.01  ? 334 ALA B N     1 
ATOM   6647  C CA    . ALA B 1 334 ? -33.436 33.254  -52.240  1.00 43.03  ? 334 ALA B CA    1 
ATOM   6648  C C     . ALA B 1 334 ? -32.998 33.111  -50.780  1.00 42.75  ? 334 ALA B C     1 
ATOM   6649  O O     . ALA B 1 334 ? -33.816 32.761  -49.918  1.00 38.17  ? 334 ALA B O     1 
ATOM   6650  C CB    . ALA B 1 334 ? -33.204 31.970  -52.986  1.00 41.47  ? 334 ALA B CB    1 
ATOM   6651  N N     . ILE B 1 335 ? -31.706 33.354  -50.526  1.00 41.48  ? 335 ILE B N     1 
ATOM   6652  C CA    . ILE B 1 335 ? -31.138 33.203  -49.197  1.00 49.94  ? 335 ILE B CA    1 
ATOM   6653  C C     . ILE B 1 335 ? -31.681 34.311  -48.311  1.00 49.46  ? 335 ILE B C     1 
ATOM   6654  O O     . ILE B 1 335 ? -32.278 34.035  -47.292  1.00 54.41  ? 335 ILE B O     1 
ATOM   6655  C CB    . ILE B 1 335 ? -29.601 33.210  -49.230  1.00 52.86  ? 335 ILE B CB    1 
ATOM   6656  C CG1   . ILE B 1 335 ? -29.045 31.969  -49.938  1.00 49.06  ? 335 ILE B CG1   1 
ATOM   6657  C CG2   . ILE B 1 335 ? -29.054 33.362  -47.816  1.00 55.05  ? 335 ILE B CG2   1 
ATOM   6658  C CD1   . ILE B 1 335 ? -27.673 32.172  -50.503  1.00 48.87  ? 335 ILE B CD1   1 
ATOM   6659  N N     . ARG B 1 336 ? -31.515 35.553  -48.751  1.00 58.33  ? 336 ARG B N     1 
ATOM   6660  C CA    . ARG B 1 336 ? -31.967 36.708  -48.002  1.00 62.75  ? 336 ARG B CA    1 
ATOM   6661  C C     . ARG B 1 336 ? -33.462 36.585  -47.696  1.00 62.63  ? 336 ARG B C     1 
ATOM   6662  O O     . ARG B 1 336 ? -33.895 36.768  -46.556  1.00 59.28  ? 336 ARG B O     1 
ATOM   6663  C CB    . ARG B 1 336 ? -31.639 37.971  -48.807  1.00 79.43  ? 336 ARG B CB    1 
ATOM   6664  C CG    . ARG B 1 336 ? -31.752 39.274  -48.030  1.00 77.99  ? 336 ARG B CG    1 
ATOM   6665  C CD    . ARG B 1 336 ? -31.938 40.470  -48.936  1.00 79.41  ? 336 ARG B CD    1 
ATOM   6666  N NE    . ARG B 1 336 ? -32.282 41.599  -48.091  1.00 90.63  ? 336 ARG B NE    1 
ATOM   6667  C CZ    . ARG B 1 336 ? -31.412 42.490  -47.628  1.00 82.39  ? 336 ARG B CZ    1 
ATOM   6668  N NH1   . ARG B 1 336 ? -30.190 42.581  -48.140  1.00 73.26  ? 336 ARG B NH1   1 
ATOM   6669  N NH2   . ARG B 1 336 ? -31.795 43.294  -46.651  1.00 73.65  ? 336 ARG B NH2   1 
ATOM   6670  N N     . ASP B 1 337 ? -34.265 36.251  -48.709  1.00 62.39  ? 337 ASP B N     1 
ATOM   6671  C CA    . ASP B 1 337 ? -35.699 36.229  -48.499  1.00 56.73  ? 337 ASP B CA    1 
ATOM   6672  C C     . ASP B 1 337 ? -36.076 35.105  -47.535  1.00 59.77  ? 337 ASP B C     1 
ATOM   6673  O O     . ASP B 1 337 ? -37.166 35.145  -46.956  1.00 64.38  ? 337 ASP B O     1 
ATOM   6674  C CB    . ASP B 1 337 ? -36.458 36.223  -49.823  1.00 55.91  ? 337 ASP B CB    1 
ATOM   6675  C CG    . ASP B 1 337 ? -36.550 37.616  -50.418  1.00 71.35  ? 337 ASP B CG    1 
ATOM   6676  O OD1   . ASP B 1 337 ? -37.082 38.516  -49.718  1.00 85.38  ? 337 ASP B OD1   1 
ATOM   6677  O OD2   . ASP B 1 337 ? -36.064 37.810  -51.548  1.00 68.76  ? 337 ASP B OD2   1 
ATOM   6678  N N     . SER B 1 338 ? -35.179 34.124  -47.321  1.00 52.08  ? 338 SER B N     1 
ATOM   6679  C CA    . SER B 1 338 ? -35.477 33.059  -46.369  1.00 48.37  ? 338 SER B CA    1 
ATOM   6680  C C     . SER B 1 338 ? -35.307 33.550  -44.935  1.00 48.22  ? 338 SER B C     1 
ATOM   6681  O O     . SER B 1 338 ? -35.752 32.856  -44.042  1.00 49.02  ? 338 SER B O     1 
ATOM   6682  C CB    . SER B 1 338 ? -34.631 31.838  -46.566  1.00 47.03  ? 338 SER B CB    1 
ATOM   6683  O OG    . SER B 1 338 ? -34.622 31.409  -47.915  1.00 48.96  ? 338 SER B OG    1 
ATOM   6684  N N     . PHE B 1 339 ? -34.655 34.709  -44.716  1.00 48.81  ? 339 PHE B N     1 
ATOM   6685  C CA    . PHE B 1 339 ? -34.332 35.165  -43.371  1.00 52.17  ? 339 PHE B CA    1 
ATOM   6686  C C     . PHE B 1 339 ? -34.892 36.552  -43.040  1.00 45.47  ? 339 PHE B C     1 
ATOM   6687  O O     . PHE B 1 339 ? -34.983 36.877  -41.863  1.00 47.60  ? 339 PHE B O     1 
ATOM   6688  C CB    . PHE B 1 339 ? -32.812 35.146  -43.154  1.00 54.36  ? 339 PHE B CB    1 
ATOM   6689  C CG    . PHE B 1 339 ? -32.182 33.776  -43.180  1.00 51.80  ? 339 PHE B CG    1 
ATOM   6690  C CD1   . PHE B 1 339 ? -32.365 32.890  -42.132  1.00 50.96  ? 339 PHE B CD1   1 
ATOM   6691  C CD2   . PHE B 1 339 ? -31.425 33.362  -44.271  1.00 51.49  ? 339 PHE B CD2   1 
ATOM   6692  C CE1   . PHE B 1 339 ? -31.767 31.636  -42.159  1.00 53.35  ? 339 PHE B CE1   1 
ATOM   6693  C CE2   . PHE B 1 339 ? -30.861 32.098  -44.313  1.00 51.01  ? 339 PHE B CE2   1 
ATOM   6694  C CZ    . PHE B 1 339 ? -31.027 31.237  -43.253  1.00 54.58  ? 339 PHE B CZ    1 
ATOM   6695  N N     . ALA B 1 340 ? -35.264 37.355  -44.044  1.00 47.36  ? 340 ALA B N     1 
ATOM   6696  C CA    . ALA B 1 340 ? -35.738 38.738  -43.878  1.00 56.53  ? 340 ALA B CA    1 
ATOM   6697  C C     . ALA B 1 340 ? -36.699 38.988  -42.707  1.00 54.65  ? 340 ALA B C     1 
ATOM   6698  O O     . ALA B 1 340 ? -36.522 39.972  -41.989  1.00 52.08  ? 340 ALA B O     1 
ATOM   6699  C CB    . ALA B 1 340 ? -36.434 39.199  -45.133  1.00 59.36  ? 340 ALA B CB    1 
ATOM   6700  N N     . ASP B 1 341 ? -37.757 38.174  -42.558  1.00 58.89  ? 341 ASP B N     1 
ATOM   6701  C CA    . ASP B 1 341 ? -38.847 38.473  -41.621  1.00 59.07  ? 341 ASP B CA    1 
ATOM   6702  C C     . ASP B 1 341 ? -38.539 38.092  -40.159  1.00 61.87  ? 341 ASP B C     1 
ATOM   6703  O O     . ASP B 1 341 ? -39.382 38.312  -39.291  1.00 57.55  ? 341 ASP B O     1 
ATOM   6704  C CB    . ASP B 1 341 ? -40.147 37.787  -42.052  1.00 60.42  ? 341 ASP B CB    1 
ATOM   6705  C CG    . ASP B 1 341 ? -40.147 36.276  -41.855  1.00 64.89  ? 341 ASP B CG    1 
ATOM   6706  O OD1   . ASP B 1 341 ? -39.185 35.644  -42.273  1.00 61.66  ? 341 ASP B OD1   1 
ATOM   6707  O OD2   . ASP B 1 341 ? -41.110 35.746  -41.281  1.00 68.65  ? 341 ASP B OD2   1 
ATOM   6708  N N     . ILE B 1 342 ? -37.345 37.553  -39.846  1.00 57.52  ? 342 ILE B N     1 
ATOM   6709  C CA    . ILE B 1 342 ? -36.955 37.355  -38.451  1.00 61.30  ? 342 ILE B CA    1 
ATOM   6710  C C     . ILE B 1 342 ? -36.654 38.710  -37.784  1.00 60.10  ? 342 ILE B C     1 
ATOM   6711  O O     . ILE B 1 342 ? -35.826 39.512  -38.241  1.00 47.55  ? 342 ILE B O     1 
ATOM   6712  C CB    . ILE B 1 342 ? -35.753 36.389  -38.326  1.00 61.95  ? 342 ILE B CB    1 
ATOM   6713  C CG1   . ILE B 1 342 ? -36.015 35.033  -38.995  1.00 57.73  ? 342 ILE B CG1   1 
ATOM   6714  C CG2   . ILE B 1 342 ? -35.354 36.212  -36.866  1.00 60.18  ? 342 ILE B CG2   1 
ATOM   6715  C CD1   . ILE B 1 342 ? -34.763 34.276  -39.376  1.00 54.22  ? 342 ILE B CD1   1 
ATOM   6716  N N     . PRO B 1 343 ? -37.330 39.031  -36.662  1.00 55.72  ? 343 PRO B N     1 
ATOM   6717  C CA    . PRO B 1 343 ? -36.913 40.146  -35.811  1.00 54.19  ? 343 PRO B CA    1 
ATOM   6718  C C     . PRO B 1 343 ? -35.436 40.145  -35.406  1.00 54.39  ? 343 PRO B C     1 
ATOM   6719  O O     . PRO B 1 343 ? -34.936 39.190  -34.809  1.00 54.20  ? 343 PRO B O     1 
ATOM   6720  C CB    . PRO B 1 343 ? -37.815 39.953  -34.585  1.00 56.16  ? 343 PRO B CB    1 
ATOM   6721  C CG    . PRO B 1 343 ? -39.087 39.424  -35.195  1.00 55.08  ? 343 PRO B CG    1 
ATOM   6722  C CD    . PRO B 1 343 ? -38.576 38.409  -36.200  1.00 57.80  ? 343 PRO B CD    1 
ATOM   6723  N N     . GLY B 1 344 ? -34.749 41.239  -35.760  1.00 50.40  ? 344 GLY B N     1 
ATOM   6724  C CA    . GLY B 1 344 ? -33.408 41.535  -35.301  1.00 43.66  ? 344 GLY B CA    1 
ATOM   6725  C C     . GLY B 1 344 ? -32.360 41.146  -36.335  1.00 48.42  ? 344 GLY B C     1 
ATOM   6726  O O     . GLY B 1 344 ? -31.168 41.304  -36.085  1.00 48.70  ? 344 GLY B O     1 
ATOM   6727  N N     . VAL B 1 345 ? -32.799 40.607  -37.478  1.00 47.95  ? 345 VAL B N     1 
ATOM   6728  C CA    . VAL B 1 345 ? -31.847 40.088  -38.439  1.00 47.67  ? 345 VAL B CA    1 
ATOM   6729  C C     . VAL B 1 345 ? -31.146 41.262  -39.112  1.00 49.69  ? 345 VAL B C     1 
ATOM   6730  O O     . VAL B 1 345 ? -31.776 42.272  -39.430  1.00 52.36  ? 345 VAL B O     1 
ATOM   6731  C CB    . VAL B 1 345 ? -32.502 39.159  -39.479  1.00 49.14  ? 345 VAL B CB    1 
ATOM   6732  C CG1   . VAL B 1 345 ? -33.393 39.907  -40.455  1.00 45.94  ? 345 VAL B CG1   1 
ATOM   6733  C CG2   . VAL B 1 345 ? -31.455 38.361  -40.242  1.00 49.35  ? 345 VAL B CG2   1 
ATOM   6734  N N     . LYS B 1 346 ? -29.838 41.087  -39.337  1.00 50.17  ? 346 LYS B N     1 
ATOM   6735  C CA    . LYS B 1 346 ? -29.035 42.075  -40.037  1.00 53.28  ? 346 LYS B CA    1 
ATOM   6736  C C     . LYS B 1 346 ? -28.188 41.352  -41.078  1.00 47.42  ? 346 LYS B C     1 
ATOM   6737  O O     . LYS B 1 346 ? -27.664 40.276  -40.798  1.00 46.83  ? 346 LYS B O     1 
ATOM   6738  C CB    . LYS B 1 346 ? -28.178 42.878  -39.048  1.00 56.37  ? 346 LYS B CB    1 
ATOM   6739  C CG    . LYS B 1 346 ? -28.932 43.629  -37.946  1.00 56.55  ? 346 LYS B CG    1 
ATOM   6740  C CD    . LYS B 1 346 ? -28.002 44.361  -36.979  1.00 62.92  ? 346 LYS B CD    1 
ATOM   6741  C CE    . LYS B 1 346 ? -28.568 45.634  -36.368  1.00 61.16  ? 346 LYS B CE    1 
ATOM   6742  N NZ    . LYS B 1 346 ? -28.987 45.449  -34.959  1.00 59.24  ? 346 LYS B NZ    1 
ATOM   6743  N N     . PHE B 1 347 ? -28.060 41.956  -42.271  1.00 47.06  ? 347 PHE B N     1 
ATOM   6744  C CA    . PHE B 1 347 ? -27.274 41.370  -43.351  1.00 49.40  ? 347 PHE B CA    1 
ATOM   6745  C C     . PHE B 1 347 ? -26.042 42.218  -43.629  1.00 44.96  ? 347 PHE B C     1 
ATOM   6746  O O     . PHE B 1 347 ? -26.135 43.433  -43.658  1.00 47.63  ? 347 PHE B O     1 
ATOM   6747  C CB    . PHE B 1 347 ? -28.112 41.237  -44.621  1.00 46.82  ? 347 PHE B CB    1 
ATOM   6748  C CG    . PHE B 1 347 ? -29.442 40.555  -44.425  1.00 47.54  ? 347 PHE B CG    1 
ATOM   6749  C CD1   . PHE B 1 347 ? -30.522 41.243  -43.898  1.00 45.49  ? 347 PHE B CD1   1 
ATOM   6750  C CD2   . PHE B 1 347 ? -29.606 39.214  -44.757  1.00 49.41  ? 347 PHE B CD2   1 
ATOM   6751  C CE1   . PHE B 1 347 ? -31.755 40.619  -43.759  1.00 52.99  ? 347 PHE B CE1   1 
ATOM   6752  C CE2   . PHE B 1 347 ? -30.829 38.582  -44.585  1.00 46.89  ? 347 PHE B CE2   1 
ATOM   6753  C CZ    . PHE B 1 347 ? -31.908 39.287  -44.105  1.00 47.27  ? 347 PHE B CZ    1 
ATOM   6754  N N     . TYR B 1 348 ? -24.897 41.574  -43.855  1.00 45.42  ? 348 TYR B N     1 
ATOM   6755  C CA    . TYR B 1 348 ? -23.639 42.297  -43.992  1.00 49.53  ? 348 TYR B CA    1 
ATOM   6756  C C     . TYR B 1 348 ? -22.847 41.727  -45.159  1.00 49.75  ? 348 TYR B C     1 
ATOM   6757  O O     . TYR B 1 348 ? -22.613 40.525  -45.206  1.00 41.44  ? 348 TYR B O     1 
ATOM   6758  C CB    . TYR B 1 348 ? -22.771 42.179  -42.724  1.00 57.60  ? 348 TYR B CB    1 
ATOM   6759  C CG    . TYR B 1 348 ? -23.318 42.825  -41.465  1.00 59.01  ? 348 TYR B CG    1 
ATOM   6760  C CD1   . TYR B 1 348 ? -23.214 44.189  -41.249  1.00 56.30  ? 348 TYR B CD1   1 
ATOM   6761  C CD2   . TYR B 1 348 ? -23.941 42.070  -40.484  1.00 57.29  ? 348 TYR B CD2   1 
ATOM   6762  C CE1   . TYR B 1 348 ? -23.700 44.779  -40.098  1.00 55.84  ? 348 TYR B CE1   1 
ATOM   6763  C CE2   . TYR B 1 348 ? -24.430 42.640  -39.323  1.00 52.65  ? 348 TYR B CE2   1 
ATOM   6764  C CZ    . TYR B 1 348 ? -24.312 44.003  -39.132  1.00 61.45  ? 348 TYR B CZ    1 
ATOM   6765  O OH    . TYR B 1 348 ? -24.806 44.581  -37.991  1.00 58.06  ? 348 TYR B OH    1 
ATOM   6766  N N     . PHE B 1 349 ? -22.446 42.598  -46.093  1.00 52.56  ? 349 PHE B N     1 
ATOM   6767  C CA    . PHE B 1 349 ? -21.351 42.281  -46.991  1.00 51.63  ? 349 PHE B CA    1 
ATOM   6768  C C     . PHE B 1 349 ? -20.063 42.900  -46.428  1.00 48.18  ? 349 PHE B C     1 
ATOM   6769  O O     . PHE B 1 349 ? -20.115 43.751  -45.545  1.00 48.15  ? 349 PHE B O     1 
ATOM   6770  C CB    . PHE B 1 349 ? -21.767 42.704  -48.401  1.00 62.72  ? 349 PHE B CB    1 
ATOM   6771  C CG    . PHE B 1 349 ? -22.905 41.897  -48.983  1.00 68.54  ? 349 PHE B CG    1 
ATOM   6772  C CD1   . PHE B 1 349 ? -22.721 40.562  -49.331  1.00 70.48  ? 349 PHE B CD1   1 
ATOM   6773  C CD2   . PHE B 1 349 ? -24.155 42.466  -49.177  1.00 72.85  ? 349 PHE B CD2   1 
ATOM   6774  C CE1   . PHE B 1 349 ? -23.760 39.813  -49.853  1.00 69.40  ? 349 PHE B CE1   1 
ATOM   6775  C CE2   . PHE B 1 349 ? -25.192 41.716  -49.704  1.00 80.03  ? 349 PHE B CE2   1 
ATOM   6776  C CZ    . PHE B 1 349 ? -24.996 40.391  -50.031  1.00 77.11  ? 349 PHE B CZ    1 
ATOM   6777  N N     . PRO B 1 350 ? -18.854 42.530  -46.900  1.00 41.07  ? 350 PRO B N     1 
ATOM   6778  C CA    . PRO B 1 350 ? -17.617 43.052  -46.310  1.00 45.33  ? 350 PRO B CA    1 
ATOM   6779  C C     . PRO B 1 350 ? -17.475 44.578  -46.273  1.00 55.29  ? 350 PRO B C     1 
ATOM   6780  O O     . PRO B 1 350 ? -16.952 45.134  -45.296  1.00 59.99  ? 350 PRO B O     1 
ATOM   6781  C CB    . PRO B 1 350 ? -16.524 42.428  -47.192  1.00 44.50  ? 350 PRO B CB    1 
ATOM   6782  C CG    . PRO B 1 350 ? -17.176 41.182  -47.764  1.00 43.68  ? 350 PRO B CG    1 
ATOM   6783  C CD    . PRO B 1 350 ? -18.609 41.605  -48.015  1.00 41.72  ? 350 PRO B CD    1 
ATOM   6784  N N     . GLU B 1 351 ? -17.941 45.252  -47.336  1.00 58.27  ? 351 GLU B N     1 
ATOM   6785  C CA    . GLU B 1 351 ? -18.053 46.704  -47.354  1.00 60.74  ? 351 GLU B CA    1 
ATOM   6786  C C     . GLU B 1 351 ? -18.930 47.221  -46.204  1.00 60.53  ? 351 GLU B C     1 
ATOM   6787  O O     . GLU B 1 351 ? -18.690 48.326  -45.737  1.00 60.49  ? 351 GLU B O     1 
ATOM   6788  C CB    . GLU B 1 351 ? -18.571 47.233  -48.698  1.00 64.81  ? 351 GLU B CB    1 
ATOM   6789  C CG    . GLU B 1 351 ? -19.947 46.724  -49.113  1.00 70.51  ? 351 GLU B CG    1 
ATOM   6790  C CD    . GLU B 1 351 ? -19.978 45.451  -49.954  1.00 74.05  ? 351 GLU B CD    1 
ATOM   6791  O OE1   . GLU B 1 351 ? -18.947 44.747  -50.039  1.00 66.70  ? 351 GLU B OE1   1 
ATOM   6792  O OE2   . GLU B 1 351 ? -21.049 45.153  -50.522  1.00 74.08  ? 351 GLU B OE2   1 
ATOM   6793  N N     . ASP B 1 352 ? -19.909 46.445  -45.711  1.00 54.63  ? 352 ASP B N     1 
ATOM   6794  C CA    . ASP B 1 352 ? -20.762 46.902  -44.621  1.00 53.77  ? 352 ASP B CA    1 
ATOM   6795  C C     . ASP B 1 352 ? -20.143 46.697  -43.229  1.00 48.28  ? 352 ASP B C     1 
ATOM   6796  O O     . ASP B 1 352 ? -20.767 47.057  -42.230  1.00 44.82  ? 352 ASP B O     1 
ATOM   6797  C CB    . ASP B 1 352 ? -22.112 46.194  -44.626  1.00 57.91  ? 352 ASP B CB    1 
ATOM   6798  C CG    . ASP B 1 352 ? -22.821 46.287  -45.955  1.00 63.27  ? 352 ASP B CG    1 
ATOM   6799  O OD1   . ASP B 1 352 ? -23.217 47.412  -46.297  1.00 63.15  ? 352 ASP B OD1   1 
ATOM   6800  O OD2   . ASP B 1 352 ? -22.945 45.225  -46.631  1.00 58.19  ? 352 ASP B OD2   1 
ATOM   6801  N N     . ARG B 1 353 ? -18.932 46.138  -43.137  1.00 48.23  ? 353 ARG B N     1 
ATOM   6802  C CA    . ARG B 1 353 ? -18.285 45.944  -41.846  1.00 52.16  ? 353 ARG B CA    1 
ATOM   6803  C C     . ARG B 1 353 ? -17.421 47.157  -41.493  1.00 51.71  ? 353 ARG B C     1 
ATOM   6804  O O     . ARG B 1 353 ? -16.504 47.521  -42.219  1.00 52.99  ? 353 ARG B O     1 
ATOM   6805  C CB    . ARG B 1 353 ? -17.405 44.691  -41.840  1.00 49.53  ? 353 ARG B CB    1 
ATOM   6806  C CG    . ARG B 1 353 ? -18.122 43.406  -42.223  1.00 49.09  ? 353 ARG B CG    1 
ATOM   6807  C CD    . ARG B 1 353 ? -19.276 43.032  -41.305  1.00 45.40  ? 353 ARG B CD    1 
ATOM   6808  N NE    . ARG B 1 353 ? -18.837 42.495  -40.024  1.00 37.23  ? 353 ARG B NE    1 
ATOM   6809  C CZ    . ARG B 1 353 ? -19.611 42.447  -38.951  1.00 36.36  ? 353 ARG B CZ    1 
ATOM   6810  N NH1   . ARG B 1 353 ? -20.930 42.521  -39.070  1.00 33.19  ? 353 ARG B NH1   1 
ATOM   6811  N NH2   . ARG B 1 353 ? -19.063 42.249  -37.770  1.00 35.55  ? 353 ARG B NH2   1 
ATOM   6812  N N     . ARG B 1 354 ? -17.693 47.752  -40.334  1.00 55.43  ? 354 ARG B N     1 
ATOM   6813  C CA    . ARG B 1 354 ? -17.051 48.997  -39.951  1.00 51.16  ? 354 ARG B CA    1 
ATOM   6814  C C     . ARG B 1 354 ? -15.685 48.728  -39.316  1.00 51.43  ? 354 ARG B C     1 
ATOM   6815  O O     . ARG B 1 354 ? -14.838 49.606  -39.303  1.00 51.54  ? 354 ARG B O     1 
ATOM   6816  C CB    . ARG B 1 354 ? -18.011 49.823  -39.089  1.00 52.64  ? 354 ARG B CB    1 
ATOM   6817  C CG    . ARG B 1 354 ? -18.406 49.214  -37.752  1.00 51.72  ? 354 ARG B CG    1 
ATOM   6818  C CD    . ARG B 1 354 ? -19.567 50.000  -37.173  1.00 50.68  ? 354 ARG B CD    1 
ATOM   6819  N NE    . ARG B 1 354 ? -20.026 49.499  -35.883  1.00 54.42  ? 354 ARG B NE    1 
ATOM   6820  C CZ    . ARG B 1 354 ? -19.381 49.618  -34.730  1.00 71.13  ? 354 ARG B CZ    1 
ATOM   6821  N NH1   . ARG B 1 354 ? -18.336 50.418  -34.621  1.00 91.24  ? 354 ARG B NH1   1 
ATOM   6822  N NH2   . ARG B 1 354 ? -19.806 48.969  -33.661  1.00 81.10  ? 354 ARG B NH2   1 
ATOM   6823  N N     . HIS B 1 355 ? -15.420 47.516  -38.837  1.00 49.29  ? 355 HIS B N     1 
ATOM   6824  C CA    . HIS B 1 355 ? -14.112 47.229  -38.282  1.00 46.36  ? 355 HIS B CA    1 
ATOM   6825  C C     . HIS B 1 355 ? -13.189 46.623  -39.340  1.00 44.02  ? 355 HIS B C     1 
ATOM   6826  O O     . HIS B 1 355 ? -13.600 45.767  -40.099  1.00 58.59  ? 355 HIS B O     1 
ATOM   6827  C CB    . HIS B 1 355 ? -14.224 46.263  -37.091  1.00 48.41  ? 355 HIS B CB    1 
ATOM   6828  C CG    . HIS B 1 355 ? -15.215 46.610  -36.033  1.00 41.74  ? 355 HIS B CG    1 
ATOM   6829  N ND1   . HIS B 1 355 ? -14.815 46.850  -34.742  1.00 39.74  ? 355 HIS B ND1   1 
ATOM   6830  C CD2   . HIS B 1 355 ? -16.571 46.651  -36.017  1.00 45.53  ? 355 HIS B CD2   1 
ATOM   6831  C CE1   . HIS B 1 355 ? -15.894 47.092  -33.987  1.00 46.35  ? 355 HIS B CE1   1 
ATOM   6832  N NE2   . HIS B 1 355 ? -16.977 46.962  -34.738  1.00 43.60  ? 355 HIS B NE2   1 
ATOM   6833  N N     . LYS B 1 356 ? -11.918 47.034  -39.333  1.00 55.87  ? 356 LYS B N     1 
ATOM   6834  C CA    . LYS B 1 356 ? -10.909 46.619  -40.300  1.00 54.23  ? 356 LYS B CA    1 
ATOM   6835  C C     . LYS B 1 356 ? -10.413 45.233  -39.937  1.00 51.40  ? 356 LYS B C     1 
ATOM   6836  O O     . LYS B 1 356 ? -9.925  44.511  -40.811  1.00 52.78  ? 356 LYS B O     1 
ATOM   6837  C CB    . LYS B 1 356 ? -9.677  47.540  -40.332  1.00 55.36  ? 356 LYS B CB    1 
ATOM   6838  C CG    . LYS B 1 356 ? -9.764  48.725  -41.291  1.00 70.54  ? 356 LYS B CG    1 
ATOM   6839  C CD    . LYS B 1 356 ? -8.470  49.009  -42.069  1.00 77.42  ? 356 LYS B CD    1 
ATOM   6840  C CE    . LYS B 1 356 ? -8.654  49.901  -43.284  1.00 79.44  ? 356 LYS B CE    1 
ATOM   6841  N NZ    . LYS B 1 356 ? -8.228  51.296  -43.027  1.00 76.58  ? 356 LYS B NZ    1 
ATOM   6842  N N     . VAL B 1 357 ? -10.463 44.937  -38.631  1.00 49.73  ? 357 VAL B N     1 
ATOM   6843  C CA    . VAL B 1 357 ? -10.171 43.616  -38.097  1.00 53.95  ? 357 VAL B CA    1 
ATOM   6844  C C     . VAL B 1 357 ? -11.505 43.068  -37.617  1.00 49.90  ? 357 VAL B C     1 
ATOM   6845  O O     . VAL B 1 357 ? -12.182 43.733  -36.849  1.00 54.02  ? 357 VAL B O     1 
ATOM   6846  C CB    . VAL B 1 357 ? -9.097  43.659  -36.990  1.00 62.10  ? 357 VAL B CB    1 
ATOM   6847  C CG1   . VAL B 1 357 ? -9.030  42.361  -36.193  1.00 66.85  ? 357 VAL B CG1   1 
ATOM   6848  C CG2   . VAL B 1 357 ? -7.722  44.001  -37.545  1.00 51.59  ? 357 VAL B CG2   1 
ATOM   6849  N N     . ASP B 1 358 ? -11.941 41.945  -38.196  1.00 49.75  ? 358 ASP B N     1 
ATOM   6850  C CA    . ASP B 1 358 ? -13.360 41.617  -38.192  1.00 50.61  ? 358 ASP B CA    1 
ATOM   6851  C C     . ASP B 1 358 ? -13.596 40.174  -38.637  1.00 54.75  ? 358 ASP B C     1 
ATOM   6852  O O     . ASP B 1 358 ? -12.839 39.607  -39.435  1.00 56.60  ? 358 ASP B O     1 
ATOM   6853  C CB    . ASP B 1 358 ? -14.143 42.598  -39.056  1.00 46.25  ? 358 ASP B CB    1 
ATOM   6854  C CG    . ASP B 1 358 ? -15.641 42.374  -39.036  1.00 51.86  ? 358 ASP B CG    1 
ATOM   6855  O OD1   . ASP B 1 358 ? -16.070 41.418  -39.676  1.00 62.00  ? 358 ASP B OD1   1 
ATOM   6856  O OD2   . ASP B 1 358 ? -16.373 43.163  -38.369  1.00 46.62  ? 358 ASP B OD2   1 
ATOM   6857  N N     . LEU B 1 359 ? -14.673 39.592  -38.098  1.00 53.12  ? 359 LEU B N     1 
ATOM   6858  C CA    . LEU B 1 359 ? -14.987 38.195  -38.336  1.00 54.54  ? 359 LEU B CA    1 
ATOM   6859  C C     . LEU B 1 359 ? -15.200 37.906  -39.828  1.00 52.53  ? 359 LEU B C     1 
ATOM   6860  O O     . LEU B 1 359 ? -14.619 36.956  -40.356  1.00 47.26  ? 359 LEU B O     1 
ATOM   6861  C CB    . LEU B 1 359 ? -16.250 37.809  -37.562  1.00 57.70  ? 359 LEU B CB    1 
ATOM   6862  C CG    . LEU B 1 359 ? -16.824 36.473  -38.028  1.00 63.38  ? 359 LEU B CG    1 
ATOM   6863  C CD1   . LEU B 1 359 ? -16.067 35.323  -37.371  1.00 57.90  ? 359 LEU B CD1   1 
ATOM   6864  C CD2   . LEU B 1 359 ? -18.319 36.415  -37.811  1.00 64.29  ? 359 LEU B CD2   1 
ATOM   6865  N N     . LEU B 1 360 ? -16.102 38.658  -40.477  1.00 50.67  ? 360 LEU B N     1 
ATOM   6866  C CA    . LEU B 1 360 ? -16.412 38.457  -41.889  1.00 53.03  ? 360 LEU B CA    1 
ATOM   6867  C C     . LEU B 1 360 ? -15.167 38.619  -42.764  1.00 55.10  ? 360 LEU B C     1 
ATOM   6868  O O     . LEU B 1 360 ? -15.038 37.906  -43.765  1.00 61.06  ? 360 LEU B O     1 
ATOM   6869  C CB    . LEU B 1 360 ? -17.522 39.411  -42.355  1.00 51.85  ? 360 LEU B CB    1 
ATOM   6870  C CG    . LEU B 1 360 ? -17.885 39.308  -43.840  1.00 54.35  ? 360 LEU B CG    1 
ATOM   6871  C CD1   . LEU B 1 360 ? -18.252 37.874  -44.226  1.00 54.39  ? 360 LEU B CD1   1 
ATOM   6872  C CD2   . LEU B 1 360 ? -19.035 40.244  -44.203  1.00 51.80  ? 360 LEU B CD2   1 
ATOM   6873  N N     . LEU B 1 361 ? -14.250 39.536  -42.412  1.00 50.75  ? 361 LEU B N     1 
ATOM   6874  C CA    . LEU B 1 361 ? -13.102 39.751  -43.274  1.00 50.20  ? 361 LEU B CA    1 
ATOM   6875  C C     . LEU B 1 361 ? -12.146 38.575  -43.145  1.00 49.20  ? 361 LEU B C     1 
ATOM   6876  O O     . LEU B 1 361 ? -11.461 38.257  -44.120  1.00 46.75  ? 361 LEU B O     1 
ATOM   6877  C CB    . LEU B 1 361 ? -12.435 41.095  -42.962  1.00 52.89  ? 361 LEU B CB    1 
ATOM   6878  C CG    . LEU B 1 361 ? -13.326 42.335  -43.104  1.00 56.61  ? 361 LEU B CG    1 
ATOM   6879  C CD1   . LEU B 1 361 ? -12.495 43.569  -43.402  1.00 60.88  ? 361 LEU B CD1   1 
ATOM   6880  C CD2   . LEU B 1 361 ? -14.398 42.179  -44.171  1.00 58.66  ? 361 LEU B CD2   1 
ATOM   6881  N N     . HIS B 1 362 ? -12.094 37.952  -41.948  1.00 54.06  ? 362 HIS B N     1 
ATOM   6882  C CA    . HIS B 1 362 ? -11.281 36.750  -41.743  1.00 61.13  ? 362 HIS B CA    1 
ATOM   6883  C C     . HIS B 1 362 ? -11.910 35.543  -42.461  1.00 55.12  ? 362 HIS B C     1 
ATOM   6884  O O     . HIS B 1 362 ? -11.193 34.740  -43.047  1.00 52.02  ? 362 HIS B O     1 
ATOM   6885  C CB    . HIS B 1 362 ? -10.909 36.517  -40.263  1.00 61.94  ? 362 HIS B CB    1 
ATOM   6886  C CG    . HIS B 1 362 ? -9.976  37.571  -39.676  1.00 97.60  ? 362 HIS B CG    1 
ATOM   6887  N ND1   . HIS B 1 362 ? -9.373  37.478  -38.430  1.00 93.99  ? 362 HIS B ND1   1 
ATOM   6888  C CD2   . HIS B 1 362 ? -9.548  38.764  -40.179  1.00 102.35 ? 362 HIS B CD2   1 
ATOM   6889  C CE1   . HIS B 1 362 ? -8.635  38.561  -38.196  1.00 74.01  ? 362 HIS B CE1   1 
ATOM   6890  N NE2   . HIS B 1 362 ? -8.733  39.357  -39.243  1.00 87.97  ? 362 HIS B NE2   1 
ATOM   6891  N N     . ARG B 1 363 ? -13.242 35.400  -42.433  1.00 47.93  ? 363 ARG B N     1 
ATOM   6892  C CA    . ARG B 1 363 ? -13.886 34.220  -42.978  1.00 50.97  ? 363 ARG B CA    1 
ATOM   6893  C C     . ARG B 1 363 ? -13.992 34.301  -44.508  1.00 55.32  ? 363 ARG B C     1 
ATOM   6894  O O     . ARG B 1 363 ? -14.013 33.270  -45.198  1.00 47.91  ? 363 ARG B O     1 
ATOM   6895  C CB    . ARG B 1 363 ? -15.216 34.022  -42.254  1.00 55.03  ? 363 ARG B CB    1 
ATOM   6896  C CG    . ARG B 1 363 ? -15.023 33.732  -40.774  1.00 65.66  ? 363 ARG B CG    1 
ATOM   6897  C CD    . ARG B 1 363 ? -15.982 32.705  -40.233  1.00 74.53  ? 363 ARG B CD    1 
ATOM   6898  N NE    . ARG B 1 363 ? -15.592 31.402  -40.730  1.00 85.34  ? 363 ARG B NE    1 
ATOM   6899  C CZ    . ARG B 1 363 ? -14.564 30.690  -40.276  1.00 90.82  ? 363 ARG B CZ    1 
ATOM   6900  N NH1   . ARG B 1 363 ? -13.889 31.102  -39.211  1.00 89.24  ? 363 ARG B NH1   1 
ATOM   6901  N NH2   . ARG B 1 363 ? -14.264 29.536  -40.858  1.00 78.40  ? 363 ARG B NH2   1 
ATOM   6902  N N     . ALA B 1 364 ? -13.988 35.530  -45.040  1.00 57.39  ? 364 ALA B N     1 
ATOM   6903  C CA    . ALA B 1 364 ? -13.920 35.743  -46.475  1.00 58.70  ? 364 ALA B CA    1 
ATOM   6904  C C     . ALA B 1 364 ? -12.665 35.093  -47.051  1.00 55.15  ? 364 ALA B C     1 
ATOM   6905  O O     . ALA B 1 364 ? -12.685 34.624  -48.180  1.00 69.03  ? 364 ALA B O     1 
ATOM   6906  C CB    . ALA B 1 364 ? -13.990 37.214  -46.815  1.00 56.44  ? 364 ALA B CB    1 
ATOM   6907  N N     . GLU B 1 365 ? -11.592 35.009  -46.270  1.00 53.47  ? 365 GLU B N     1 
ATOM   6908  C CA    . GLU B 1 365 ? -10.357 34.416  -46.759  1.00 54.06  ? 365 GLU B CA    1 
ATOM   6909  C C     . GLU B 1 365 ? -10.479 32.894  -46.728  1.00 57.25  ? 365 GLU B C     1 
ATOM   6910  O O     . GLU B 1 365 ? -9.968  32.218  -47.626  1.00 62.07  ? 365 GLU B O     1 
ATOM   6911  C CB    . GLU B 1 365 ? -9.156  34.956  -45.963  1.00 60.45  ? 365 GLU B CB    1 
ATOM   6912  C CG    . GLU B 1 365 ? -8.868  36.457  -46.204  1.00 67.75  ? 365 GLU B CG    1 
ATOM   6913  C CD    . GLU B 1 365 ? -8.413  36.868  -47.609  1.00 75.20  ? 365 GLU B CD    1 
ATOM   6914  O OE1   . GLU B 1 365 ? -7.212  36.681  -47.910  1.00 74.57  ? 365 GLU B OE1   1 
ATOM   6915  O OE2   . GLU B 1 365 ? -9.258  37.363  -48.426  1.00 79.81  ? 365 GLU B OE2   1 
ATOM   6916  N N     . THR B 1 366 ? -11.172 32.358  -45.712  1.00 49.27  ? 366 THR B N     1 
ATOM   6917  C CA    . THR B 1 366 ? -11.294 30.914  -45.562  1.00 50.63  ? 366 THR B CA    1 
ATOM   6918  C C     . THR B 1 366 ? -12.240 30.325  -46.612  1.00 44.95  ? 366 THR B C     1 
ATOM   6919  O O     . THR B 1 366 ? -12.061 29.212  -47.107  1.00 40.17  ? 366 THR B O     1 
ATOM   6920  C CB    . THR B 1 366 ? -11.788 30.554  -44.153  1.00 53.12  ? 366 THR B CB    1 
ATOM   6921  O OG1   . THR B 1 366 ? -11.042 31.313  -43.204  1.00 52.31  ? 366 THR B OG1   1 
ATOM   6922  C CG2   . THR B 1 366 ? -11.603 29.093  -43.830  1.00 47.74  ? 366 THR B CG2   1 
ATOM   6923  N N     . MET B 1 367 ? -13.293 31.071  -46.917  1.00 42.07  ? 367 MET B N     1 
ATOM   6924  C CA    . MET B 1 367 ? -14.340 30.560  -47.763  1.00 38.97  ? 367 MET B CA    1 
ATOM   6925  C C     . MET B 1 367 ? -13.944 30.640  -49.250  1.00 52.38  ? 367 MET B C     1 
ATOM   6926  O O     . MET B 1 367 ? -14.688 30.124  -50.100  1.00 47.12  ? 367 MET B O     1 
ATOM   6927  C CB    . MET B 1 367 ? -15.615 31.342  -47.448  1.00 41.37  ? 367 MET B CB    1 
ATOM   6928  C CG    . MET B 1 367 ? -16.380 30.739  -46.265  1.00 42.30  ? 367 MET B CG    1 
ATOM   6929  S SD    . MET B 1 367 ? -17.971 31.523  -45.904  1.00 47.35  ? 367 MET B SD    1 
ATOM   6930  C CE    . MET B 1 367 ? -17.444 33.234  -45.842  1.00 46.64  ? 367 MET B CE    1 
ATOM   6931  N N     . LYS B 1 368 ? -12.751 31.202  -49.574  1.00 48.86  ? 368 LYS B N     1 
ATOM   6932  C CA    . LYS B 1 368 ? -12.207 31.059  -50.920  1.00 47.06  ? 368 LYS B CA    1 
ATOM   6933  C C     . LYS B 1 368 ? -10.884 30.315  -50.889  1.00 48.03  ? 368 LYS B C     1 
ATOM   6934  O O     . LYS B 1 368 ? -10.147 30.293  -51.869  1.00 50.81  ? 368 LYS B O     1 
ATOM   6935  C CB    . LYS B 1 368 ? -12.057 32.388  -51.664  1.00 53.12  ? 368 LYS B CB    1 
ATOM   6936  C CG    . LYS B 1 368 ? -11.015 33.362  -51.138  1.00 61.49  ? 368 LYS B CG    1 
ATOM   6937  C CD    . LYS B 1 368 ? -10.822 34.564  -52.043  1.00 66.82  ? 368 LYS B CD    1 
ATOM   6938  C CE    . LYS B 1 368 ? -10.135 35.718  -51.347  1.00 75.09  ? 368 LYS B CE    1 
ATOM   6939  N NZ    . LYS B 1 368 ? -9.928  36.853  -52.271  1.00 81.29  ? 368 LYS B NZ    1 
ATOM   6940  N N     . GLY B 1 369 ? -10.594 29.666  -49.768  1.00 48.34  ? 369 GLY B N     1 
ATOM   6941  C CA    . GLY B 1 369 ? -9.559  28.648  -49.758  1.00 45.64  ? 369 GLY B CA    1 
ATOM   6942  C C     . GLY B 1 369 ? -8.154  29.177  -49.471  1.00 47.97  ? 369 GLY B C     1 
ATOM   6943  O O     . GLY B 1 369 ? -7.198  28.449  -49.742  1.00 53.86  ? 369 GLY B O     1 
ATOM   6944  N N     . VAL B 1 370 ? -8.042  30.374  -48.855  1.00 47.51  ? 370 VAL B N     1 
ATOM   6945  C CA    . VAL B 1 370 ? -6.751  30.939  -48.482  1.00 48.34  ? 370 VAL B CA    1 
ATOM   6946  C C     . VAL B 1 370 ? -6.400  30.499  -47.063  1.00 46.26  ? 370 VAL B C     1 
ATOM   6947  O O     . VAL B 1 370 ? -7.093  30.803  -46.116  1.00 47.58  ? 370 VAL B O     1 
ATOM   6948  C CB    . VAL B 1 370 ? -6.691  32.474  -48.599  1.00 50.59  ? 370 VAL B CB    1 
ATOM   6949  C CG1   . VAL B 1 370 ? -5.274  32.954  -48.303  1.00 49.17  ? 370 VAL B CG1   1 
ATOM   6950  C CG2   . VAL B 1 370 ? -7.158  32.992  -49.966  1.00 46.39  ? 370 VAL B CG2   1 
ATOM   6951  N N     . PRO B 1 371 ? -5.302  29.756  -46.860  1.00 50.24  ? 371 PRO B N     1 
ATOM   6952  C CA    . PRO B 1 371 ? -4.948  29.287  -45.530  1.00 57.58  ? 371 PRO B CA    1 
ATOM   6953  C C     . PRO B 1 371 ? -4.334  30.419  -44.721  1.00 57.57  ? 371 PRO B C     1 
ATOM   6954  O O     . PRO B 1 371 ? -3.376  31.019  -45.188  1.00 47.86  ? 371 PRO B O     1 
ATOM   6955  C CB    . PRO B 1 371 ? -3.945  28.147  -45.813  1.00 52.05  ? 371 PRO B CB    1 
ATOM   6956  C CG    . PRO B 1 371 ? -3.292  28.537  -47.123  1.00 53.06  ? 371 PRO B CG    1 
ATOM   6957  C CD    . PRO B 1 371 ? -4.380  29.254  -47.897  1.00 54.20  ? 371 PRO B CD    1 
ATOM   6958  N N     . LYS B 1 372 ? -4.935  30.694  -43.551  1.00 70.39  ? 372 LYS B N     1 
ATOM   6959  C CA    . LYS B 1 372 ? -4.434  31.639  -42.561  1.00 77.25  ? 372 LYS B CA    1 
ATOM   6960  C C     . LYS B 1 372 ? -4.330  30.910  -41.219  1.00 79.90  ? 372 LYS B C     1 
ATOM   6961  O O     . LYS B 1 372 ? -4.772  29.769  -41.098  1.00 83.02  ? 372 LYS B O     1 
ATOM   6962  C CB    . LYS B 1 372 ? -5.367  32.854  -42.471  1.00 75.70  ? 372 LYS B CB    1 
ATOM   6963  C CG    . LYS B 1 372 ? -5.398  33.791  -43.677  1.00 85.31  ? 372 LYS B CG    1 
ATOM   6964  C CD    . LYS B 1 372 ? -6.437  34.935  -43.558  1.00 103.95 ? 372 LYS B CD    1 
ATOM   6965  C CE    . LYS B 1 372 ? -6.077  36.039  -42.571  1.00 108.74 ? 372 LYS B CE    1 
ATOM   6966  N NZ    . LYS B 1 372 ? -7.205  36.957  -42.248  1.00 93.72  ? 372 LYS B NZ    1 
ATOM   6967  N N     . LEU B 1 373 ? -3.747  31.570  -40.209  1.00 97.35  ? 373 LEU B N     1 
ATOM   6968  C CA    . LEU B 1 373 ? -3.555  30.962  -38.898  1.00 94.20  ? 373 LEU B CA    1 
ATOM   6969  C C     . LEU B 1 373 ? -4.499  31.563  -37.862  1.00 86.30  ? 373 LEU B C     1 
ATOM   6970  O O     . LEU B 1 373 ? -4.524  31.099  -36.728  1.00 84.06  ? 373 LEU B O     1 
ATOM   6971  C CB    . LEU B 1 373 ? -2.099  31.159  -38.459  1.00 93.77  ? 373 LEU B CB    1 
ATOM   6972  C CG    . LEU B 1 373 ? -1.092  30.164  -39.040  1.00 100.13 ? 373 LEU B CG    1 
ATOM   6973  C CD1   . LEU B 1 373 ? 0.324   30.498  -38.584  1.00 90.10  ? 373 LEU B CD1   1 
ATOM   6974  C CD2   . LEU B 1 373 ? -1.457  28.718  -38.681  1.00 100.01 ? 373 LEU B CD2   1 
ATOM   6975  N N     . THR B 1 374 ? -5.307  32.546  -38.269  1.00 86.49  ? 374 THR B N     1 
ATOM   6976  C CA    . THR B 1 374 ? -5.941  33.460  -37.332  1.00 93.11  ? 374 THR B CA    1 
ATOM   6977  C C     . THR B 1 374 ? -7.144  32.841  -36.612  1.00 90.28  ? 374 THR B C     1 
ATOM   6978  O O     . THR B 1 374 ? -7.726  33.505  -35.752  1.00 102.51 ? 374 THR B O     1 
ATOM   6979  C CB    . THR B 1 374 ? -6.338  34.777  -38.019  1.00 98.84  ? 374 THR B CB    1 
ATOM   6980  O OG1   . THR B 1 374 ? -7.412  34.524  -38.926  1.00 101.11 ? 374 THR B OG1   1 
ATOM   6981  C CG2   . THR B 1 374 ? -5.178  35.438  -38.740  1.00 102.07 ? 374 THR B CG2   1 
ATOM   6982  N N     . GLU B 1 375 ? -7.526  31.587  -36.908  1.00 84.27  ? 375 GLU B N     1 
ATOM   6983  C CA    . GLU B 1 375 ? -8.633  30.990  -36.167  1.00 88.57  ? 375 GLU B CA    1 
ATOM   6984  C C     . GLU B 1 375 ? -8.166  30.520  -34.783  1.00 88.83  ? 375 GLU B C     1 
ATOM   6985  O O     . GLU B 1 375 ? -8.918  30.676  -33.816  1.00 89.45  ? 375 GLU B O     1 
ATOM   6986  C CB    . GLU B 1 375 ? -9.305  29.861  -36.945  1.00 82.34  ? 375 GLU B CB    1 
ATOM   6987  C CG    . GLU B 1 375 ? -10.429 29.162  -36.164  1.00 80.87  ? 375 GLU B CG    1 
ATOM   6988  C CD    . GLU B 1 375 ? -11.844 29.732  -36.210  1.00 77.29  ? 375 GLU B CD    1 
ATOM   6989  O OE1   . GLU B 1 375 ? -12.113 30.670  -37.007  1.00 72.64  ? 375 GLU B OE1   1 
ATOM   6990  O OE2   . GLU B 1 375 ? -12.690 29.216  -35.447  1.00 68.34  ? 375 GLU B OE2   1 
ATOM   6991  N N     . PHE B 1 376 ? -6.922  30.004  -34.684  1.00 78.63  ? 376 PHE B N     1 
ATOM   6992  C CA    . PHE B 1 376 ? -6.330  29.560  -33.422  1.00 77.47  ? 376 PHE B CA    1 
ATOM   6993  C C     . PHE B 1 376 ? -6.334  30.674  -32.362  1.00 71.09  ? 376 PHE B C     1 
ATOM   6994  O O     . PHE B 1 376 ? -5.874  30.466  -31.235  1.00 64.81  ? 376 PHE B O     1 
ATOM   6995  C CB    . PHE B 1 376 ? -4.906  29.018  -33.634  1.00 78.36  ? 376 PHE B CB    1 
ATOM   6996  C CG    . PHE B 1 376 ? -4.790  27.635  -34.243  1.00 80.46  ? 376 PHE B CG    1 
ATOM   6997  C CD1   . PHE B 1 376 ? -5.216  27.373  -35.542  1.00 73.15  ? 376 PHE B CD1   1 
ATOM   6998  C CD2   . PHE B 1 376 ? -4.227  26.588  -33.520  1.00 74.85  ? 376 PHE B CD2   1 
ATOM   6999  C CE1   . PHE B 1 376 ? -5.088  26.108  -36.096  1.00 66.40  ? 376 PHE B CE1   1 
ATOM   7000  C CE2   . PHE B 1 376 ? -4.090  25.322  -34.082  1.00 71.64  ? 376 PHE B CE2   1 
ATOM   7001  C CZ    . PHE B 1 376 ? -4.516  25.087  -35.372  1.00 68.20  ? 376 PHE B CZ    1 
ATOM   7002  N N     . ASN B 1 377 ? -6.877  31.846  -32.721  1.00 66.87  ? 377 ASN B N     1 
ATOM   7003  C CA    . ASN B 1 377 ? -7.036  32.966  -31.809  1.00 76.29  ? 377 ASN B CA    1 
ATOM   7004  C C     . ASN B 1 377 ? -8.103  32.695  -30.750  1.00 72.51  ? 377 ASN B C     1 
ATOM   7005  O O     . ASN B 1 377 ? -8.043  33.313  -29.686  1.00 75.03  ? 377 ASN B O     1 
ATOM   7006  C CB    . ASN B 1 377 ? -7.365  34.267  -32.550  1.00 78.17  ? 377 ASN B CB    1 
ATOM   7007  C CG    . ASN B 1 377 ? -6.200  34.802  -33.363  1.00 77.13  ? 377 ASN B CG    1 
ATOM   7008  O OD1   . ASN B 1 377 ? -5.086  34.276  -33.338  1.00 82.66  ? 377 ASN B OD1   1 
ATOM   7009  N ND2   . ASN B 1 377 ? -6.456  35.844  -34.126  1.00 71.38  ? 377 ASN B ND2   1 
ATOM   7010  N N     . PHE B 1 378 ? -9.067  31.797  -31.025  1.00 67.63  ? 378 PHE B N     1 
ATOM   7011  C CA    . PHE B 1 378 ? -10.095 31.487  -30.033  1.00 64.61  ? 378 PHE B CA    1 
ATOM   7012  C C     . PHE B 1 378 ? -9.475  30.794  -28.809  1.00 58.14  ? 378 PHE B C     1 
ATOM   7013  O O     . PHE B 1 378 ? -10.055 30.845  -27.727  1.00 59.76  ? 378 PHE B O     1 
ATOM   7014  C CB    . PHE B 1 378 ? -11.308 30.757  -30.645  1.00 69.23  ? 378 PHE B CB    1 
ATOM   7015  C CG    . PHE B 1 378 ? -11.183 29.280  -30.964  1.00 64.02  ? 378 PHE B CG    1 
ATOM   7016  C CD1   . PHE B 1 378 ? -10.843 28.346  -29.991  1.00 56.90  ? 378 PHE B CD1   1 
ATOM   7017  C CD2   . PHE B 1 378 ? -11.472 28.814  -32.237  1.00 63.91  ? 378 PHE B CD2   1 
ATOM   7018  C CE1   . PHE B 1 378 ? -10.711 27.000  -30.294  1.00 53.32  ? 378 PHE B CE1   1 
ATOM   7019  C CE2   . PHE B 1 378 ? -11.376 27.460  -32.533  1.00 64.64  ? 378 PHE B CE2   1 
ATOM   7020  C CZ    . PHE B 1 378 ? -10.997 26.555  -31.558  1.00 61.49  ? 378 PHE B CZ    1 
ATOM   7021  N N     . LEU B 1 379 ? -8.295  30.177  -28.963  1.00 55.54  ? 379 LEU B N     1 
ATOM   7022  C CA    . LEU B 1 379 ? -7.602  29.547  -27.847  1.00 56.33  ? 379 LEU B CA    1 
ATOM   7023  C C     . LEU B 1 379 ? -7.135  30.575  -26.813  1.00 58.10  ? 379 LEU B C     1 
ATOM   7024  O O     . LEU B 1 379 ? -6.901  30.193  -25.660  1.00 63.05  ? 379 LEU B O     1 
ATOM   7025  C CB    . LEU B 1 379 ? -6.413  28.728  -28.372  1.00 60.06  ? 379 LEU B CB    1 
ATOM   7026  C CG    . LEU B 1 379 ? -6.743  27.565  -29.319  1.00 64.77  ? 379 LEU B CG    1 
ATOM   7027  C CD1   . LEU B 1 379 ? -5.510  26.735  -29.636  1.00 60.31  ? 379 LEU B CD1   1 
ATOM   7028  C CD2   . LEU B 1 379 ? -7.800  26.643  -28.741  1.00 73.55  ? 379 LEU B CD2   1 
ATOM   7029  N N     . ASN B 1 380 ? -7.011  31.860  -27.208  1.00 52.35  ? 380 ASN B N     1 
ATOM   7030  C CA    . ASN B 1 380 ? -6.565  32.919  -26.306  1.00 52.97  ? 380 ASN B CA    1 
ATOM   7031  C C     . ASN B 1 380 ? -7.716  33.464  -25.464  1.00 54.94  ? 380 ASN B C     1 
ATOM   7032  O O     . ASN B 1 380 ? -7.483  34.307  -24.600  1.00 52.40  ? 380 ASN B O     1 
ATOM   7033  C CB    . ASN B 1 380 ? -5.933  34.119  -27.028  1.00 64.12  ? 380 ASN B CB    1 
ATOM   7034  C CG    . ASN B 1 380 ? -4.684  33.765  -27.817  1.00 69.17  ? 380 ASN B CG    1 
ATOM   7035  O OD1   . ASN B 1 380 ? -3.841  32.998  -27.350  1.00 74.89  ? 380 ASN B OD1   1 
ATOM   7036  N ND2   . ASN B 1 380 ? -4.578  34.283  -29.030  1.00 64.86  ? 380 ASN B ND2   1 
ATOM   7037  N N     . TRP B 1 381 ? -8.940  32.962  -25.689  1.00 49.87  ? 381 TRP B N     1 
ATOM   7038  C CA    . TRP B 1 381 ? -10.134 33.549  -25.104  1.00 45.28  ? 381 TRP B CA    1 
ATOM   7039  C C     . TRP B 1 381 ? -10.054 33.687  -23.586  1.00 46.56  ? 381 TRP B C     1 
ATOM   7040  O O     . TRP B 1 381 ? -10.469 34.714  -23.064  1.00 50.80  ? 381 TRP B O     1 
ATOM   7041  C CB    . TRP B 1 381 ? -11.376 32.748  -25.484  1.00 41.86  ? 381 TRP B CB    1 
ATOM   7042  C CG    . TRP B 1 381 ? -12.583 33.227  -24.752  1.00 37.61  ? 381 TRP B CG    1 
ATOM   7043  C CD1   . TRP B 1 381 ? -13.216 32.590  -23.729  1.00 45.24  ? 381 TRP B CD1   1 
ATOM   7044  C CD2   . TRP B 1 381 ? -13.332 34.423  -24.995  1.00 32.55  ? 381 TRP B CD2   1 
ATOM   7045  N NE1   . TRP B 1 381 ? -14.305 33.311  -23.318  1.00 42.11  ? 381 TRP B NE1   1 
ATOM   7046  C CE2   . TRP B 1 381 ? -14.410 34.426  -24.097  1.00 36.31  ? 381 TRP B CE2   1 
ATOM   7047  C CE3   . TRP B 1 381 ? -13.207 35.487  -25.891  1.00 37.58  ? 381 TRP B CE3   1 
ATOM   7048  C CZ2   . TRP B 1 381 ? -15.333 35.464  -24.038  1.00 44.80  ? 381 TRP B CZ2   1 
ATOM   7049  C CZ3   . TRP B 1 381 ? -14.138 36.505  -25.861  1.00 39.77  ? 381 TRP B CZ3   1 
ATOM   7050  C CH2   . TRP B 1 381 ? -15.186 36.488  -24.943  1.00 44.25  ? 381 TRP B CH2   1 
ATOM   7051  N N     . ASP B 1 382 ? -9.584  32.649  -22.882  1.00 54.34  ? 382 ASP B N     1 
ATOM   7052  C CA    . ASP B 1 382 ? -9.505  32.685  -21.425  1.00 61.28  ? 382 ASP B CA    1 
ATOM   7053  C C     . ASP B 1 382 ? -8.039  32.619  -20.979  1.00 62.23  ? 382 ASP B C     1 
ATOM   7054  O O     . ASP B 1 382 ? -7.725  32.067  -19.927  1.00 54.68  ? 382 ASP B O     1 
ATOM   7055  C CB    . ASP B 1 382 ? -10.371 31.586  -20.785  1.00 66.00  ? 382 ASP B CB    1 
ATOM   7056  C CG    . ASP B 1 382 ? -10.548 31.714  -19.276  1.00 70.72  ? 382 ASP B CG    1 
ATOM   7057  O OD1   . ASP B 1 382 ? -10.360 32.823  -18.748  1.00 84.38  ? 382 ASP B OD1   1 
ATOM   7058  O OD2   . ASP B 1 382 ? -10.854 30.704  -18.627  1.00 77.55  ? 382 ASP B OD2   1 
ATOM   7059  N N     . GLY B 1 383 ? -7.134  33.193  -21.784  1.00 73.79  ? 383 GLY B N     1 
ATOM   7060  C CA    . GLY B 1 383 ? -5.787  33.507  -21.327  1.00 73.16  ? 383 GLY B CA    1 
ATOM   7061  C C     . GLY B 1 383 ? -4.719  32.594  -21.920  1.00 73.53  ? 383 GLY B C     1 
ATOM   7062  O O     . GLY B 1 383 ? -3.537  32.771  -21.644  1.00 89.86  ? 383 GLY B O     1 
ATOM   7063  N N     . GLY B 1 384 ? -5.129  31.635  -22.748  1.00 72.23  ? 384 GLY B N     1 
ATOM   7064  C CA    . GLY B 1 384 ? -4.215  30.616  -23.228  1.00 73.07  ? 384 GLY B CA    1 
ATOM   7065  C C     . GLY B 1 384 ? -4.627  29.234  -22.726  1.00 76.26  ? 384 GLY B C     1 
ATOM   7066  O O     . GLY B 1 384 ? -4.718  28.976  -21.520  1.00 62.54  ? 384 GLY B O     1 
ATOM   7067  N N     . GLY B 1 385 ? -4.893  28.346  -23.683  1.00 67.19  ? 385 GLY B N     1 
ATOM   7068  C CA    . GLY B 1 385 ? -5.201  26.973  -23.359  1.00 69.88  ? 385 GLY B CA    1 
ATOM   7069  C C     . GLY B 1 385 ? -5.248  26.094  -24.601  1.00 65.71  ? 385 GLY B C     1 
ATOM   7070  O O     . GLY B 1 385 ? -4.911  26.521  -25.703  1.00 61.27  ? 385 GLY B O     1 
ATOM   7071  N N     . GLY B 1 386 ? -5.668  24.852  -24.391  1.00 61.52  ? 386 GLY B N     1 
ATOM   7072  C CA    . GLY B 1 386 ? -6.024  23.990  -25.498  1.00 69.06  ? 386 GLY B CA    1 
ATOM   7073  C C     . GLY B 1 386 ? -7.537  23.936  -25.682  1.00 67.16  ? 386 GLY B C     1 
ATOM   7074  O O     . GLY B 1 386 ? -8.293  24.432  -24.834  1.00 60.66  ? 386 GLY B O     1 
ATOM   7075  N N     . HIS B 1 387 ? -7.944  23.329  -26.803  1.00 61.65  ? 387 HIS B N     1 
ATOM   7076  C CA    . HIS B 1 387 ? -9.345  23.079  -27.065  1.00 55.48  ? 387 HIS B CA    1 
ATOM   7077  C C     . HIS B 1 387 ? -9.602  21.579  -27.077  1.00 59.34  ? 387 HIS B C     1 
ATOM   7078  O O     . HIS B 1 387 ? -8.705  20.738  -27.220  1.00 59.10  ? 387 HIS B O     1 
ATOM   7079  C CB    . HIS B 1 387 ? -9.846  23.784  -28.335  1.00 53.75  ? 387 HIS B CB    1 
ATOM   7080  C CG    . HIS B 1 387 ? -9.331  23.410  -29.703  1.00 65.33  ? 387 HIS B CG    1 
ATOM   7081  N ND1   . HIS B 1 387 ? -10.257 23.107  -30.681  1.00 66.28  ? 387 HIS B ND1   1 
ATOM   7082  C CD2   . HIS B 1 387 ? -8.104  23.440  -30.328  1.00 82.01  ? 387 HIS B CD2   1 
ATOM   7083  C CE1   . HIS B 1 387 ? -9.641  22.909  -31.854  1.00 85.20  ? 387 HIS B CE1   1 
ATOM   7084  N NE2   . HIS B 1 387 ? -8.251  23.115  -31.719  1.00 82.13  ? 387 HIS B NE2   1 
ATOM   7085  N N     . VAL B 1 388 ? -10.875 21.270  -26.879  1.00 58.54  ? 388 VAL B N     1 
ATOM   7086  C CA    . VAL B 1 388 ? -11.427 20.035  -27.388  1.00 55.75  ? 388 VAL B CA    1 
ATOM   7087  C C     . VAL B 1 388 ? -12.773 20.375  -28.011  1.00 45.42  ? 388 VAL B C     1 
ATOM   7088  O O     . VAL B 1 388 ? -13.449 21.306  -27.591  1.00 48.15  ? 388 VAL B O     1 
ATOM   7089  C CB    . VAL B 1 388 ? -11.516 18.951  -26.298  1.00 58.05  ? 388 VAL B CB    1 
ATOM   7090  C CG1   . VAL B 1 388 ? -12.800 19.073  -25.490  1.00 58.58  ? 388 VAL B CG1   1 
ATOM   7091  C CG2   . VAL B 1 388 ? -11.358 17.572  -26.919  1.00 60.18  ? 388 VAL B CG2   1 
ATOM   7092  N N     . GLY B 1 389 ? -13.098 19.651  -29.072  1.00 42.41  ? 389 GLY B N     1 
ATOM   7093  C CA    . GLY B 1 389 ? -14.365 19.832  -29.734  1.00 43.51  ? 389 GLY B CA    1 
ATOM   7094  C C     . GLY B 1 389 ? -15.133 18.517  -29.859  1.00 44.82  ? 389 GLY B C     1 
ATOM   7095  O O     . GLY B 1 389 ? -14.545 17.439  -29.863  1.00 42.33  ? 389 GLY B O     1 
ATOM   7096  N N     . PHE B 1 390 ? -16.451 18.660  -29.985  1.00 39.18  ? 390 PHE B N     1 
ATOM   7097  C CA    . PHE B 1 390 ? -17.370 17.555  -30.053  1.00 43.05  ? 390 PHE B CA    1 
ATOM   7098  C C     . PHE B 1 390 ? -18.400 17.915  -31.110  1.00 40.71  ? 390 PHE B C     1 
ATOM   7099  O O     . PHE B 1 390 ? -19.107 18.897  -30.937  1.00 36.67  ? 390 PHE B O     1 
ATOM   7100  C CB    . PHE B 1 390 ? -18.006 17.346  -28.675  1.00 44.14  ? 390 PHE B CB    1 
ATOM   7101  C CG    . PHE B 1 390 ? -19.098 16.304  -28.585  1.00 43.64  ? 390 PHE B CG    1 
ATOM   7102  C CD1   . PHE B 1 390 ? -18.847 14.980  -28.920  1.00 40.53  ? 390 PHE B CD1   1 
ATOM   7103  C CD2   . PHE B 1 390 ? -20.378 16.652  -28.148  1.00 46.77  ? 390 PHE B CD2   1 
ATOM   7104  C CE1   . PHE B 1 390 ? -19.850 14.028  -28.820  1.00 45.01  ? 390 PHE B CE1   1 
ATOM   7105  C CE2   . PHE B 1 390 ? -21.388 15.705  -28.060  1.00 46.32  ? 390 PHE B CE2   1 
ATOM   7106  C CZ    . PHE B 1 390 ? -21.119 14.391  -28.395  1.00 49.84  ? 390 PHE B CZ    1 
ATOM   7107  N N     . SER B 1 391 ? -18.537 17.078  -32.143  1.00 38.74  ? 391 SER B N     1 
ATOM   7108  C CA    . SER B 1 391 ? -19.284 17.481  -33.326  1.00 45.74  ? 391 SER B CA    1 
ATOM   7109  C C     . SER B 1 391 ? -20.218 16.371  -33.820  1.00 42.41  ? 391 SER B C     1 
ATOM   7110  O O     . SER B 1 391 ? -20.204 15.986  -34.976  1.00 42.59  ? 391 SER B O     1 
ATOM   7111  C CB    . SER B 1 391 ? -18.311 17.868  -34.391  1.00 42.18  ? 391 SER B CB    1 
ATOM   7112  O OG    . SER B 1 391 ? -17.451 16.752  -34.602  1.00 42.42  ? 391 SER B OG    1 
ATOM   7113  N N     . PRO B 1 392 ? -21.144 15.875  -32.994  1.00 45.84  ? 392 PRO B N     1 
ATOM   7114  C CA    . PRO B 1 392 ? -22.045 14.814  -33.439  1.00 46.46  ? 392 PRO B CA    1 
ATOM   7115  C C     . PRO B 1 392 ? -22.992 15.199  -34.581  1.00 41.69  ? 392 PRO B C     1 
ATOM   7116  O O     . PRO B 1 392 ? -23.292 16.360  -34.799  1.00 38.22  ? 392 PRO B O     1 
ATOM   7117  C CB    . PRO B 1 392 ? -22.818 14.543  -32.143  1.00 50.54  ? 392 PRO B CB    1 
ATOM   7118  C CG    . PRO B 1 392 ? -22.840 15.874  -31.454  1.00 44.42  ? 392 PRO B CG    1 
ATOM   7119  C CD    . PRO B 1 392 ? -21.412 16.328  -31.620  1.00 46.37  ? 392 PRO B CD    1 
ATOM   7120  N N     . VAL B 1 393 ? -23.472 14.176  -35.286  1.00 40.69  ? 393 VAL B N     1 
ATOM   7121  C CA    . VAL B 1 393 ? -24.373 14.311  -36.416  1.00 39.23  ? 393 VAL B CA    1 
ATOM   7122  C C     . VAL B 1 393 ? -25.834 14.232  -35.967  1.00 39.96  ? 393 VAL B C     1 
ATOM   7123  O O     . VAL B 1 393 ? -26.206 13.410  -35.132  1.00 33.47  ? 393 VAL B O     1 
ATOM   7124  C CB    . VAL B 1 393 ? -24.165 13.179  -37.429  1.00 39.33  ? 393 VAL B CB    1 
ATOM   7125  C CG1   . VAL B 1 393 ? -24.990 13.448  -38.660  1.00 44.16  ? 393 VAL B CG1   1 
ATOM   7126  C CG2   . VAL B 1 393 ? -22.710 12.974  -37.784  1.00 43.82  ? 393 VAL B CG2   1 
ATOM   7127  N N     . SER B 1 394 ? -26.670 15.022  -36.637  1.00 36.18  ? 394 SER B N     1 
ATOM   7128  C CA    . SER B 1 394 ? -28.076 15.090  -36.327  1.00 35.57  ? 394 SER B CA    1 
ATOM   7129  C C     . SER B 1 394 ? -28.790 15.550  -37.586  1.00 38.68  ? 394 SER B C     1 
ATOM   7130  O O     . SER B 1 394 ? -28.128 16.019  -38.501  1.00 40.58  ? 394 SER B O     1 
ATOM   7131  C CB    . SER B 1 394 ? -28.347 15.979  -35.140  1.00 36.85  ? 394 SER B CB    1 
ATOM   7132  O OG    . SER B 1 394 ? -28.127 17.351  -35.408  1.00 36.51  ? 394 SER B OG    1 
ATOM   7133  N N     . PRO B 1 395 ? -30.115 15.325  -37.683  1.00 34.24  ? 395 PRO B N     1 
ATOM   7134  C CA    . PRO B 1 395 ? -30.922 15.849  -38.773  1.00 35.14  ? 395 PRO B CA    1 
ATOM   7135  C C     . PRO B 1 395 ? -30.997 17.373  -38.727  1.00 39.36  ? 395 PRO B C     1 
ATOM   7136  O O     . PRO B 1 395 ? -30.981 17.957  -37.636  1.00 39.23  ? 395 PRO B O     1 
ATOM   7137  C CB    . PRO B 1 395 ? -32.342 15.281  -38.499  1.00 37.58  ? 395 PRO B CB    1 
ATOM   7138  C CG    . PRO B 1 395 ? -32.161 14.180  -37.452  1.00 37.11  ? 395 PRO B CG    1 
ATOM   7139  C CD    . PRO B 1 395 ? -30.888 14.518  -36.723  1.00 37.19  ? 395 PRO B CD    1 
ATOM   7140  N N     . ILE B 1 396 ? -31.107 17.990  -39.910  1.00 37.97  ? 396 ILE B N     1 
ATOM   7141  C CA    . ILE B 1 396 ? -31.262 19.435  -40.039  1.00 41.34  ? 396 ILE B CA    1 
ATOM   7142  C C     . ILE B 1 396 ? -32.699 19.828  -39.659  1.00 39.17  ? 396 ILE B C     1 
ATOM   7143  O O     . ILE B 1 396 ? -33.549 20.028  -40.508  1.00 39.96  ? 396 ILE B O     1 
ATOM   7144  C CB    . ILE B 1 396 ? -30.929 19.952  -41.460  1.00 38.11  ? 396 ILE B CB    1 
ATOM   7145  C CG1   . ILE B 1 396 ? -29.633 19.377  -42.034  1.00 40.80  ? 396 ILE B CG1   1 
ATOM   7146  C CG2   . ILE B 1 396 ? -30.900 21.478  -41.464  1.00 39.73  ? 396 ILE B CG2   1 
ATOM   7147  C CD1   . ILE B 1 396 ? -29.465 19.602  -43.532  1.00 39.31  ? 396 ILE B CD1   1 
ATOM   7148  N N     . THR B 1 397 ? -32.907 20.074  -38.375  1.00 43.00  ? 397 THR B N     1 
ATOM   7149  C CA    . THR B 1 397 ? -34.183 20.411  -37.776  1.00 44.08  ? 397 THR B CA    1 
ATOM   7150  C C     . THR B 1 397 ? -33.924 21.459  -36.706  1.00 42.28  ? 397 THR B C     1 
ATOM   7151  O O     . THR B 1 397 ? -32.907 21.379  -36.021  1.00 43.64  ? 397 THR B O     1 
ATOM   7152  C CB    . THR B 1 397 ? -34.740 19.128  -37.154  1.00 48.50  ? 397 THR B CB    1 
ATOM   7153  O OG1   . THR B 1 397 ? -35.392 18.451  -38.224  1.00 53.43  ? 397 THR B OG1   1 
ATOM   7154  C CG2   . THR B 1 397 ? -35.678 19.327  -36.001  1.00 52.09  ? 397 THR B CG2   1 
ATOM   7155  N N     . GLY B 1 398 ? -34.852 22.405  -36.572  1.00 41.79  ? 398 GLY B N     1 
ATOM   7156  C CA    . GLY B 1 398 ? -34.880 23.373  -35.492  1.00 39.28  ? 398 GLY B CA    1 
ATOM   7157  C C     . GLY B 1 398 ? -34.862 22.689  -34.132  1.00 42.03  ? 398 GLY B C     1 
ATOM   7158  O O     . GLY B 1 398 ? -33.940 22.896  -33.356  1.00 52.03  ? 398 GLY B O     1 
ATOM   7159  N N     . LYS B 1 399 ? -35.866 21.852  -33.883  1.00 45.59  ? 399 LYS B N     1 
ATOM   7160  C CA    . LYS B 1 399 ? -36.010 21.092  -32.648  1.00 53.32  ? 399 LYS B CA    1 
ATOM   7161  C C     . LYS B 1 399 ? -34.662 20.460  -32.252  1.00 48.47  ? 399 LYS B C     1 
ATOM   7162  O O     . LYS B 1 399 ? -34.236 20.555  -31.101  1.00 47.90  ? 399 LYS B O     1 
ATOM   7163  C CB    . LYS B 1 399 ? -37.211 20.158  -32.845  1.00 55.71  ? 399 LYS B CB    1 
ATOM   7164  C CG    . LYS B 1 399 ? -37.445 19.109  -31.773  1.00 78.06  ? 399 LYS B CG    1 
ATOM   7165  C CD    . LYS B 1 399 ? -38.511 18.090  -32.162  1.00 92.45  ? 399 LYS B CD    1 
ATOM   7166  C CE    . LYS B 1 399 ? -38.728 17.036  -31.094  1.00 106.24 ? 399 LYS B CE    1 
ATOM   7167  N NZ    . LYS B 1 399 ? -39.956 16.243  -31.344  1.00 108.18 ? 399 LYS B NZ    1 
ATOM   7168  N N     . ASP B 1 400 ? -33.937 19.906  -33.223  1.00 41.82  ? 400 ASP B N     1 
ATOM   7169  C CA    . ASP B 1 400 ? -32.685 19.214  -32.968  1.00 46.93  ? 400 ASP B CA    1 
ATOM   7170  C C     . ASP B 1 400 ? -31.554 20.183  -32.614  1.00 48.24  ? 400 ASP B C     1 
ATOM   7171  O O     . ASP B 1 400 ? -30.691 19.871  -31.794  1.00 48.13  ? 400 ASP B O     1 
ATOM   7172  C CB    . ASP B 1 400 ? -32.263 18.424  -34.208  1.00 47.35  ? 400 ASP B CB    1 
ATOM   7173  C CG    . ASP B 1 400 ? -32.940 17.075  -34.299  1.00 42.60  ? 400 ASP B CG    1 
ATOM   7174  O OD1   . ASP B 1 400 ? -32.806 16.342  -33.317  1.00 39.90  ? 400 ASP B OD1   1 
ATOM   7175  O OD2   . ASP B 1 400 ? -33.584 16.782  -35.341  1.00 40.92  ? 400 ASP B OD2   1 
ATOM   7176  N N     . ALA B 1 401 ? -31.543 21.342  -33.278  1.00 44.67  ? 401 ALA B N     1 
ATOM   7177  C CA    . ALA B 1 401 ? -30.506 22.334  -33.070  1.00 45.48  ? 401 ALA B CA    1 
ATOM   7178  C C     . ALA B 1 401 ? -30.645 22.979  -31.688  1.00 43.25  ? 401 ALA B C     1 
ATOM   7179  O O     . ALA B 1 401 ? -29.658 23.136  -30.971  1.00 40.64  ? 401 ALA B O     1 
ATOM   7180  C CB    . ALA B 1 401 ? -30.557 23.353  -34.179  1.00 46.97  ? 401 ALA B CB    1 
ATOM   7181  N N     . ILE B 1 402 ? -31.868 23.349  -31.321  1.00 38.19  ? 402 ILE B N     1 
ATOM   7182  C CA    . ILE B 1 402 ? -32.064 24.104  -30.112  1.00 43.98  ? 402 ILE B CA    1 
ATOM   7183  C C     . ILE B 1 402 ? -31.921 23.158  -28.922  1.00 45.99  ? 402 ILE B C     1 
ATOM   7184  O O     . ILE B 1 402 ? -31.401 23.558  -27.875  1.00 42.24  ? 402 ILE B O     1 
ATOM   7185  C CB    . ILE B 1 402 ? -33.420 24.846  -30.115  1.00 56.26  ? 402 ILE B CB    1 
ATOM   7186  C CG1   . ILE B 1 402 ? -33.474 25.840  -28.949  1.00 62.32  ? 402 ILE B CG1   1 
ATOM   7187  C CG2   . ILE B 1 402 ? -34.597 23.877  -30.074  1.00 49.24  ? 402 ILE B CG2   1 
ATOM   7188  C CD1   . ILE B 1 402 ? -34.227 27.098  -29.237  1.00 68.79  ? 402 ILE B CD1   1 
ATOM   7189  N N     . LYS B 1 403 ? -32.383 21.909  -29.089  1.00 41.10  ? 403 LYS B N     1 
ATOM   7190  C CA    . LYS B 1 403 ? -32.195 20.908  -28.058  1.00 39.94  ? 403 LYS B CA    1 
ATOM   7191  C C     . LYS B 1 403 ? -30.694 20.736  -27.807  1.00 45.41  ? 403 LYS B C     1 
ATOM   7192  O O     . LYS B 1 403 ? -30.251 20.737  -26.656  1.00 42.86  ? 403 LYS B O     1 
ATOM   7193  C CB    . LYS B 1 403 ? -32.839 19.570  -28.446  1.00 46.27  ? 403 LYS B CB    1 
ATOM   7194  C CG    . LYS B 1 403 ? -33.098 18.597  -27.301  1.00 50.24  ? 403 LYS B CG    1 
ATOM   7195  C CD    . LYS B 1 403 ? -32.868 17.156  -27.674  1.00 62.57  ? 403 LYS B CD    1 
ATOM   7196  C CE    . LYS B 1 403 ? -33.994 16.567  -28.503  1.00 77.28  ? 403 LYS B CE    1 
ATOM   7197  N NZ    . LYS B 1 403 ? -33.562 15.357  -29.247  1.00 78.03  ? 403 LYS B NZ    1 
ATOM   7198  N N     . GLN B 1 404 ? -29.893 20.604  -28.876  1.00 41.72  ? 404 GLN B N     1 
ATOM   7199  C CA    . GLN B 1 404 ? -28.465 20.407  -28.669  1.00 44.15  ? 404 GLN B CA    1 
ATOM   7200  C C     . GLN B 1 404 ? -27.824 21.648  -28.061  1.00 43.84  ? 404 GLN B C     1 
ATOM   7201  O O     . GLN B 1 404 ? -26.888 21.521  -27.279  1.00 41.81  ? 404 GLN B O     1 
ATOM   7202  C CB    . GLN B 1 404 ? -27.751 19.989  -29.951  1.00 40.55  ? 404 GLN B CB    1 
ATOM   7203  C CG    . GLN B 1 404 ? -27.939 18.509  -30.232  1.00 41.44  ? 404 GLN B CG    1 
ATOM   7204  C CD    . GLN B 1 404 ? -27.299 18.124  -31.535  1.00 41.12  ? 404 GLN B CD    1 
ATOM   7205  O OE1   . GLN B 1 404 ? -26.152 17.682  -31.573  1.00 45.93  ? 404 GLN B OE1   1 
ATOM   7206  N NE2   . GLN B 1 404 ? -28.024 18.348  -32.615  1.00 43.17  ? 404 GLN B NE2   1 
ATOM   7207  N N     . TYR B 1 405 ? -28.330 22.832  -28.422  1.00 43.15  ? 405 TYR B N     1 
ATOM   7208  C CA    . TYR B 1 405 ? -27.831 24.070  -27.847  1.00 49.41  ? 405 TYR B CA    1 
ATOM   7209  C C     . TYR B 1 405 ? -28.166 24.117  -26.345  1.00 43.46  ? 405 TYR B C     1 
ATOM   7210  O O     . TYR B 1 405 ? -27.304 24.416  -25.526  1.00 41.00  ? 405 TYR B O     1 
ATOM   7211  C CB    . TYR B 1 405 ? -28.340 25.288  -28.636  1.00 48.22  ? 405 TYR B CB    1 
ATOM   7212  C CG    . TYR B 1 405 ? -28.211 26.588  -27.882  1.00 47.08  ? 405 TYR B CG    1 
ATOM   7213  C CD1   . TYR B 1 405 ? -26.960 27.150  -27.645  1.00 49.81  ? 405 TYR B CD1   1 
ATOM   7214  C CD2   . TYR B 1 405 ? -29.332 27.223  -27.353  1.00 44.86  ? 405 TYR B CD2   1 
ATOM   7215  C CE1   . TYR B 1 405 ? -26.831 28.319  -26.911  1.00 47.69  ? 405 TYR B CE1   1 
ATOM   7216  C CE2   . TYR B 1 405 ? -29.221 28.388  -26.613  1.00 42.03  ? 405 TYR B CE2   1 
ATOM   7217  C CZ    . TYR B 1 405 ? -27.962 28.930  -26.396  1.00 43.53  ? 405 TYR B CZ    1 
ATOM   7218  O OH    . TYR B 1 405 ? -27.819 30.056  -25.649  1.00 45.14  ? 405 TYR B OH    1 
ATOM   7219  N N     . ASN B 1 406 ? -29.408 23.796  -25.996  1.00 37.71  ? 406 ASN B N     1 
ATOM   7220  C CA    . ASN B 1 406 ? -29.850 23.826  -24.617  1.00 42.65  ? 406 ASN B CA    1 
ATOM   7221  C C     . ASN B 1 406 ? -29.052 22.840  -23.772  1.00 42.47  ? 406 ASN B C     1 
ATOM   7222  O O     . ASN B 1 406 ? -28.635 23.196  -22.680  1.00 41.08  ? 406 ASN B O     1 
ATOM   7223  C CB    . ASN B 1 406 ? -31.365 23.625  -24.511  1.00 44.84  ? 406 ASN B CB    1 
ATOM   7224  C CG    . ASN B 1 406 ? -32.145 24.846  -24.961  1.00 50.78  ? 406 ASN B CG    1 
ATOM   7225  O OD1   . ASN B 1 406 ? -31.659 25.974  -24.888  1.00 57.82  ? 406 ASN B OD1   1 
ATOM   7226  N ND2   . ASN B 1 406 ? -33.374 24.645  -25.403  1.00 49.54  ? 406 ASN B ND2   1 
ATOM   7227  N N     . MET B 1 407 ? -28.834 21.625  -24.279  1.00 46.76  ? 407 MET B N     1 
ATOM   7228  C CA    . MET B 1 407 ? -28.185 20.549  -23.539  1.00 49.93  ? 407 MET B CA    1 
ATOM   7229  C C     . MET B 1 407 ? -26.742 20.928  -23.182  1.00 52.99  ? 407 MET B C     1 
ATOM   7230  O O     . MET B 1 407 ? -26.273 20.648  -22.078  1.00 51.92  ? 407 MET B O     1 
ATOM   7231  C CB    . MET B 1 407 ? -28.103 19.278  -24.397  1.00 49.78  ? 407 MET B CB    1 
ATOM   7232  C CG    . MET B 1 407 ? -29.393 18.519  -24.544  1.00 53.22  ? 407 MET B CG    1 
ATOM   7233  S SD    . MET B 1 407 ? -29.203 17.093  -25.633  1.00 51.25  ? 407 MET B SD    1 
ATOM   7234  C CE    . MET B 1 407 ? -28.406 15.963  -24.487  1.00 46.05  ? 407 MET B CE    1 
ATOM   7235  N N     . VAL B 1 408 ? -26.018 21.480  -24.163  1.00 51.05  ? 408 VAL B N     1 
ATOM   7236  C CA    . VAL B 1 408 ? -24.584 21.702  -24.061  1.00 47.35  ? 408 VAL B CA    1 
ATOM   7237  C C     . VAL B 1 408 ? -24.273 22.990  -23.300  1.00 47.84  ? 408 VAL B C     1 
ATOM   7238  O O     . VAL B 1 408 ? -23.420 22.971  -22.417  1.00 50.81  ? 408 VAL B O     1 
ATOM   7239  C CB    . VAL B 1 408 ? -23.946 21.786  -25.447  1.00 43.68  ? 408 VAL B CB    1 
ATOM   7240  C CG1   . VAL B 1 408 ? -22.470 22.155  -25.326  1.00 46.56  ? 408 VAL B CG1   1 
ATOM   7241  C CG2   . VAL B 1 408 ? -24.148 20.496  -26.212  1.00 40.50  ? 408 VAL B CG2   1 
ATOM   7242  N N     . SER B 1 409 ? -24.926 24.100  -23.674  1.00 45.60  ? 409 SER B N     1 
ATOM   7243  C CA    . SER B 1 409 ? -24.669 25.395  -23.049  1.00 51.45  ? 409 SER B CA    1 
ATOM   7244  C C     . SER B 1 409 ? -24.999 25.381  -21.544  1.00 48.66  ? 409 SER B C     1 
ATOM   7245  O O     . SER B 1 409 ? -24.252 25.966  -20.777  1.00 39.11  ? 409 SER B O     1 
ATOM   7246  C CB    . SER B 1 409 ? -25.361 26.537  -23.773  1.00 49.98  ? 409 SER B CB    1 
ATOM   7247  O OG    . SER B 1 409 ? -26.780 26.346  -23.840  1.00 52.05  ? 409 SER B OG    1 
ATOM   7248  N N     . SER B 1 410 ? -26.094 24.730  -21.118  1.00 46.50  ? 410 SER B N     1 
ATOM   7249  C CA    . SER B 1 410 ? -26.341 24.419  -19.711  1.00 46.06  ? 410 SER B CA    1 
ATOM   7250  C C     . SER B 1 410 ? -25.127 23.768  -19.079  1.00 44.97  ? 410 SER B C     1 
ATOM   7251  O O     . SER B 1 410 ? -24.667 24.192  -18.022  1.00 50.73  ? 410 SER B O     1 
ATOM   7252  C CB    . SER B 1 410 ? -27.480 23.466  -19.508  1.00 47.55  ? 410 SER B CB    1 
ATOM   7253  O OG    . SER B 1 410 ? -28.655 23.985  -20.091  1.00 64.63  ? 410 SER B OG    1 
ATOM   7254  N N     . ARG B 1 411 ? -24.659 22.693  -19.698  1.00 39.47  ? 411 ARG B N     1 
ATOM   7255  C CA    . ARG B 1 411 ? -23.684 21.856  -19.034  1.00 44.03  ? 411 ARG B CA    1 
ATOM   7256  C C     . ARG B 1 411 ? -22.353 22.586  -18.934  1.00 43.86  ? 411 ARG B C     1 
ATOM   7257  O O     . ARG B 1 411 ? -21.784 22.639  -17.843  1.00 45.10  ? 411 ARG B O     1 
ATOM   7258  C CB    . ARG B 1 411 ? -23.533 20.546  -19.799  1.00 48.35  ? 411 ARG B CB    1 
ATOM   7259  C CG    . ARG B 1 411 ? -24.712 19.607  -19.592  1.00 53.86  ? 411 ARG B CG    1 
ATOM   7260  C CD    . ARG B 1 411 ? -24.350 18.598  -18.532  1.00 55.19  ? 411 ARG B CD    1 
ATOM   7261  N NE    . ARG B 1 411 ? -25.362 17.603  -18.245  1.00 49.76  ? 411 ARG B NE    1 
ATOM   7262  C CZ    . ARG B 1 411 ? -25.520 17.063  -17.040  1.00 53.34  ? 411 ARG B CZ    1 
ATOM   7263  N NH1   . ARG B 1 411 ? -24.785 17.483  -16.031  1.00 42.96  ? 411 ARG B NH1   1 
ATOM   7264  N NH2   . ARG B 1 411 ? -26.415 16.112  -16.838  1.00 68.17  ? 411 ARG B NH2   1 
ATOM   7265  N N     . VAL B 1 412 ? -21.885 23.108  -20.085  1.00 42.20  ? 412 VAL B N     1 
ATOM   7266  C CA    . VAL B 1 412 ? -20.620 23.835  -20.232  1.00 44.23  ? 412 VAL B CA    1 
ATOM   7267  C C     . VAL B 1 412 ? -20.545 25.045  -19.272  1.00 40.78  ? 412 VAL B C     1 
ATOM   7268  O O     . VAL B 1 412 ? -19.494 25.289  -18.661  1.00 33.43  ? 412 VAL B O     1 
ATOM   7269  C CB    . VAL B 1 412 ? -20.413 24.246  -21.711  1.00 42.11  ? 412 VAL B CB    1 
ATOM   7270  C CG1   . VAL B 1 412 ? -19.283 25.221  -21.913  1.00 46.25  ? 412 VAL B CG1   1 
ATOM   7271  C CG2   . VAL B 1 412 ? -20.171 23.037  -22.584  1.00 42.72  ? 412 VAL B CG2   1 
ATOM   7272  N N     . ARG B 1 413 ? -21.655 25.785  -19.119  1.00 34.86  ? 413 ARG B N     1 
ATOM   7273  C CA    . ARG B 1 413 ? -21.682 26.962  -18.263  1.00 38.18  ? 413 ARG B CA    1 
ATOM   7274  C C     . ARG B 1 413 ? -21.816 26.572  -16.797  1.00 41.92  ? 413 ARG B C     1 
ATOM   7275  O O     . ARG B 1 413 ? -21.386 27.315  -15.934  1.00 45.47  ? 413 ARG B O     1 
ATOM   7276  C CB    . ARG B 1 413 ? -22.761 27.959  -18.692  1.00 37.68  ? 413 ARG B CB    1 
ATOM   7277  C CG    . ARG B 1 413 ? -22.482 28.626  -20.040  1.00 41.20  ? 413 ARG B CG    1 
ATOM   7278  C CD    . ARG B 1 413 ? -23.641 29.425  -20.613  1.00 38.21  ? 413 ARG B CD    1 
ATOM   7279  N NE    . ARG B 1 413 ? -24.109 30.425  -19.650  1.00 43.94  ? 413 ARG B NE    1 
ATOM   7280  C CZ    . ARG B 1 413 ? -23.533 31.607  -19.395  1.00 47.06  ? 413 ARG B CZ    1 
ATOM   7281  N NH1   . ARG B 1 413 ? -22.452 32.011  -20.036  1.00 55.31  ? 413 ARG B NH1   1 
ATOM   7282  N NH2   . ARG B 1 413 ? -24.071 32.426  -18.516  1.00 47.07  ? 413 ARG B NH2   1 
ATOM   7283  N N     . GLU B 1 414 ? -22.354 25.389  -16.496  1.00 54.43  ? 414 GLU B N     1 
ATOM   7284  C CA    . GLU B 1 414 ? -22.368 24.926  -15.117  1.00 48.52  ? 414 GLU B CA    1 
ATOM   7285  C C     . GLU B 1 414 ? -20.941 24.622  -14.665  1.00 42.53  ? 414 GLU B C     1 
ATOM   7286  O O     . GLU B 1 414 ? -20.582 24.893  -13.524  1.00 41.64  ? 414 GLU B O     1 
ATOM   7287  C CB    . GLU B 1 414 ? -23.277 23.718  -14.936  1.00 50.94  ? 414 GLU B CB    1 
ATOM   7288  C CG    . GLU B 1 414 ? -23.157 23.135  -13.531  1.00 63.72  ? 414 GLU B CG    1 
ATOM   7289  C CD    . GLU B 1 414 ? -24.121 22.020  -13.152  1.00 67.81  ? 414 GLU B CD    1 
ATOM   7290  O OE1   . GLU B 1 414 ? -25.336 22.146  -13.467  1.00 75.00  ? 414 GLU B OE1   1 
ATOM   7291  O OE2   . GLU B 1 414 ? -23.661 21.041  -12.517  1.00 64.82  ? 414 GLU B OE2   1 
ATOM   7292  N N     . TYR B 1 415 ? -20.124 24.109  -15.582  1.00 40.90  ? 415 TYR B N     1 
ATOM   7293  C CA    . TYR B 1 415 ? -18.752 23.711  -15.280  1.00 44.14  ? 415 TYR B CA    1 
ATOM   7294  C C     . TYR B 1 415 ? -17.809 24.917  -15.288  1.00 44.33  ? 415 TYR B C     1 
ATOM   7295  O O     . TYR B 1 415 ? -16.634 24.709  -15.073  1.00 41.04  ? 415 TYR B O     1 
ATOM   7296  C CB    . TYR B 1 415 ? -18.248 22.636  -16.268  1.00 45.86  ? 415 TYR B CB    1 
ATOM   7297  C CG    . TYR B 1 415 ? -18.651 21.214  -15.924  1.00 40.45  ? 415 TYR B CG    1 
ATOM   7298  C CD1   . TYR B 1 415 ? -19.983 20.841  -15.870  1.00 33.83  ? 415 TYR B CD1   1 
ATOM   7299  C CD2   . TYR B 1 415 ? -17.696 20.249  -15.624  1.00 40.15  ? 415 TYR B CD2   1 
ATOM   7300  C CE1   . TYR B 1 415 ? -20.369 19.577  -15.466  1.00 37.09  ? 415 TYR B CE1   1 
ATOM   7301  C CE2   . TYR B 1 415 ? -18.059 18.960  -15.280  1.00 46.08  ? 415 TYR B CE2   1 
ATOM   7302  C CZ    . TYR B 1 415 ? -19.403 18.627  -15.182  1.00 47.35  ? 415 TYR B CZ    1 
ATOM   7303  O OH    . TYR B 1 415 ? -19.754 17.342  -14.826  1.00 47.24  ? 415 TYR B OH    1 
ATOM   7304  N N     . GLY B 1 416 ? -18.306 26.146  -15.561  1.00 46.48  ? 416 GLY B N     1 
ATOM   7305  C CA    . GLY B 1 416 ? -17.502 27.365  -15.515  1.00 46.23  ? 416 GLY B CA    1 
ATOM   7306  C C     . GLY B 1 416 ? -16.900 27.821  -16.863  1.00 51.10  ? 416 GLY B C     1 
ATOM   7307  O O     . GLY B 1 416 ? -16.197 28.830  -16.914  1.00 48.90  ? 416 GLY B O     1 
ATOM   7308  N N     . PHE B 1 417 ? -17.176 27.112  -17.967  1.00 46.99  ? 417 PHE B N     1 
ATOM   7309  C CA    . PHE B 1 417 ? -16.659 27.486  -19.270  1.00 45.23  ? 417 PHE B CA    1 
ATOM   7310  C C     . PHE B 1 417 ? -17.666 28.332  -20.032  1.00 41.52  ? 417 PHE B C     1 
ATOM   7311  O O     . PHE B 1 417 ? -18.868 28.265  -19.782  1.00 43.48  ? 417 PHE B O     1 
ATOM   7312  C CB    . PHE B 1 417 ? -16.370 26.239  -20.092  1.00 49.59  ? 417 PHE B CB    1 
ATOM   7313  C CG    . PHE B 1 417 ? -15.410 25.276  -19.456  1.00 46.83  ? 417 PHE B CG    1 
ATOM   7314  C CD1   . PHE B 1 417 ? -14.046 25.484  -19.538  1.00 48.74  ? 417 PHE B CD1   1 
ATOM   7315  C CD2   . PHE B 1 417 ? -15.873 24.136  -18.819  1.00 47.83  ? 417 PHE B CD2   1 
ATOM   7316  C CE1   . PHE B 1 417 ? -13.160 24.572  -18.978  1.00 52.78  ? 417 PHE B CE1   1 
ATOM   7317  C CE2   . PHE B 1 417 ? -14.990 23.200  -18.300  1.00 46.56  ? 417 PHE B CE2   1 
ATOM   7318  C CZ    . PHE B 1 417 ? -13.636 23.428  -18.364  1.00 52.36  ? 417 PHE B CZ    1 
ATOM   7319  N N     . ASP B 1 418 ? -17.180 29.107  -21.006  1.00 43.38  ? 418 ASP B N     1 
ATOM   7320  C CA    . ASP B 1 418 ? -18.101 29.828  -21.876  1.00 45.68  ? 418 ASP B CA    1 
ATOM   7321  C C     . ASP B 1 418 ? -18.564 28.857  -22.955  1.00 41.75  ? 418 ASP B C     1 
ATOM   7322  O O     . ASP B 1 418 ? -17.804 27.995  -23.372  1.00 35.13  ? 418 ASP B O     1 
ATOM   7323  C CB    . ASP B 1 418 ? -17.526 31.111  -22.473  1.00 41.50  ? 418 ASP B CB    1 
ATOM   7324  C CG    . ASP B 1 418 ? -17.540 32.314  -21.541  1.00 41.24  ? 418 ASP B CG    1 
ATOM   7325  O OD1   . ASP B 1 418 ? -18.626 32.846  -21.272  1.00 39.70  ? 418 ASP B OD1   1 
ATOM   7326  O OD2   . ASP B 1 418 ? -16.450 32.720  -21.112  1.00 38.72  ? 418 ASP B OD2   1 
ATOM   7327  N N     . TYR B 1 419 ? -19.824 29.014  -23.360  1.00 45.41  ? 419 TYR B N     1 
ATOM   7328  C CA    . TYR B 1 419 ? -20.382 28.247  -24.455  1.00 44.90  ? 419 TYR B CA    1 
ATOM   7329  C C     . TYR B 1 419 ? -19.844 28.788  -25.782  1.00 46.67  ? 419 TYR B C     1 
ATOM   7330  O O     . TYR B 1 419 ? -20.180 29.902  -26.186  1.00 40.05  ? 419 TYR B O     1 
ATOM   7331  C CB    . TYR B 1 419 ? -21.914 28.291  -24.449  1.00 39.08  ? 419 TYR B CB    1 
ATOM   7332  C CG    . TYR B 1 419 ? -22.497 27.684  -25.692  1.00 42.97  ? 419 TYR B CG    1 
ATOM   7333  C CD1   . TYR B 1 419 ? -22.391 26.326  -25.951  1.00 40.18  ? 419 TYR B CD1   1 
ATOM   7334  C CD2   . TYR B 1 419 ? -23.034 28.492  -26.676  1.00 44.86  ? 419 TYR B CD2   1 
ATOM   7335  C CE1   . TYR B 1 419 ? -22.870 25.783  -27.136  1.00 47.93  ? 419 TYR B CE1   1 
ATOM   7336  C CE2   . TYR B 1 419 ? -23.538 27.959  -27.850  1.00 47.64  ? 419 TYR B CE2   1 
ATOM   7337  C CZ    . TYR B 1 419 ? -23.460 26.602  -28.089  1.00 48.48  ? 419 TYR B CZ    1 
ATOM   7338  O OH    . TYR B 1 419 ? -23.992 26.121  -29.265  1.00 43.27  ? 419 TYR B OH    1 
ATOM   7339  N N     . MET B 1 420 ? -19.005 27.980  -26.448  1.00 51.38  ? 420 MET B N     1 
ATOM   7340  C CA    . MET B 1 420 ? -18.594 28.225  -27.826  1.00 51.20  ? 420 MET B CA    1 
ATOM   7341  C C     . MET B 1 420 ? -19.147 27.125  -28.731  1.00 48.04  ? 420 MET B C     1 
ATOM   7342  O O     . MET B 1 420 ? -18.702 25.977  -28.685  1.00 48.13  ? 420 MET B O     1 
ATOM   7343  C CB    . MET B 1 420 ? -17.070 28.215  -27.923  1.00 50.54  ? 420 MET B CB    1 
ATOM   7344  C CG    . MET B 1 420 ? -16.430 29.490  -27.513  1.00 47.96  ? 420 MET B CG    1 
ATOM   7345  S SD    . MET B 1 420 ? -14.687 29.180  -27.206  1.00 55.32  ? 420 MET B SD    1 
ATOM   7346  C CE    . MET B 1 420 ? -14.183 30.833  -26.736  1.00 61.03  ? 420 MET B CE    1 
ATOM   7347  N N     . GLY B 1 421 ? -20.143 27.471  -29.534  1.00 49.99  ? 421 GLY B N     1 
ATOM   7348  C CA    . GLY B 1 421 ? -20.810 26.491  -30.363  1.00 48.79  ? 421 GLY B CA    1 
ATOM   7349  C C     . GLY B 1 421 ? -20.990 27.002  -31.790  1.00 54.88  ? 421 GLY B C     1 
ATOM   7350  O O     . GLY B 1 421 ? -21.050 28.212  -32.027  1.00 54.02  ? 421 GLY B O     1 
ATOM   7351  N N     . LEU B 1 422 ? -21.198 26.023  -32.677  1.00 54.56  ? 422 LEU B N     1 
ATOM   7352  C CA    . LEU B 1 422 ? -21.224 26.142  -34.127  1.00 59.58  ? 422 LEU B CA    1 
ATOM   7353  C C     . LEU B 1 422 ? -22.345 25.226  -34.632  1.00 55.81  ? 422 LEU B C     1 
ATOM   7354  O O     . LEU B 1 422 ? -22.390 24.062  -34.226  1.00 47.26  ? 422 LEU B O     1 
ATOM   7355  C CB    . LEU B 1 422 ? -19.859 25.606  -34.573  1.00 65.98  ? 422 LEU B CB    1 
ATOM   7356  C CG    . LEU B 1 422 ? -19.317 26.022  -35.931  1.00 70.61  ? 422 LEU B CG    1 
ATOM   7357  C CD1   . LEU B 1 422 ? -17.931 25.434  -36.109  1.00 74.13  ? 422 LEU B CD1   1 
ATOM   7358  C CD2   . LEU B 1 422 ? -20.226 25.595  -37.064  1.00 70.75  ? 422 LEU B CD2   1 
ATOM   7359  N N     . LEU B 1 423 ? -23.262 25.712  -35.480  1.00 51.91  ? 423 LEU B N     1 
ATOM   7360  C CA    . LEU B 1 423 ? -24.148 24.800  -36.205  1.00 45.60  ? 423 LEU B CA    1 
ATOM   7361  C C     . LEU B 1 423 ? -23.726 24.755  -37.661  1.00 41.43  ? 423 LEU B C     1 
ATOM   7362  O O     . LEU B 1 423 ? -23.808 25.756  -38.363  1.00 44.78  ? 423 LEU B O     1 
ATOM   7363  C CB    . LEU B 1 423 ? -25.622 25.165  -36.033  1.00 43.36  ? 423 LEU B CB    1 
ATOM   7364  C CG    . LEU B 1 423 ? -26.129 24.747  -34.649  1.00 54.97  ? 423 LEU B CG    1 
ATOM   7365  C CD1   . LEU B 1 423 ? -27.047 25.780  -34.064  1.00 57.02  ? 423 LEU B CD1   1 
ATOM   7366  C CD2   . LEU B 1 423 ? -26.834 23.404  -34.663  1.00 55.14  ? 423 LEU B CD2   1 
ATOM   7367  N N     . ALA B 1 424 ? -23.221 23.578  -38.037  1.00 39.85  ? 424 ALA B N     1 
ATOM   7368  C CA    . ALA B 1 424 ? -22.648 23.296  -39.340  1.00 44.85  ? 424 ALA B CA    1 
ATOM   7369  C C     . ALA B 1 424 ? -23.587 22.364  -40.107  1.00 43.85  ? 424 ALA B C     1 
ATOM   7370  O O     . ALA B 1 424 ? -24.047 21.355  -39.559  1.00 41.15  ? 424 ALA B O     1 
ATOM   7371  C CB    . ALA B 1 424 ? -21.297 22.655  -39.141  1.00 41.08  ? 424 ALA B CB    1 
ATOM   7372  N N     . ILE B 1 425 ? -23.844 22.700  -41.375  1.00 41.67  ? 425 ILE B N     1 
ATOM   7373  C CA    . ILE B 1 425 ? -24.558 21.801  -42.274  1.00 43.76  ? 425 ILE B CA    1 
ATOM   7374  C C     . ILE B 1 425 ? -23.672 21.556  -43.475  1.00 38.58  ? 425 ILE B C     1 
ATOM   7375  O O     . ILE B 1 425 ? -23.195 22.514  -44.055  1.00 42.62  ? 425 ILE B O     1 
ATOM   7376  C CB    . ILE B 1 425 ? -25.924 22.351  -42.727  1.00 44.30  ? 425 ILE B CB    1 
ATOM   7377  C CG1   . ILE B 1 425 ? -26.801 22.741  -41.540  1.00 49.45  ? 425 ILE B CG1   1 
ATOM   7378  C CG2   . ILE B 1 425 ? -26.611 21.330  -43.612  1.00 45.82  ? 425 ILE B CG2   1 
ATOM   7379  C CD1   . ILE B 1 425 ? -28.063 23.491  -41.924  1.00 55.48  ? 425 ILE B CD1   1 
ATOM   7380  N N     . GLY B 1 426 ? -23.505 20.289  -43.849  1.00 40.51  ? 426 GLY B N     1 
ATOM   7381  C CA    . GLY B 1 426 ? -22.655 19.912  -44.965  1.00 45.91  ? 426 GLY B CA    1 
ATOM   7382  C C     . GLY B 1 426 ? -23.450 19.846  -46.274  1.00 54.71  ? 426 GLY B C     1 
ATOM   7383  O O     . GLY B 1 426 ? -23.330 20.723  -47.155  1.00 48.05  ? 426 GLY B O     1 
ATOM   7384  N N     . TRP B 1 427 ? -24.280 18.799  -46.370  1.00 44.12  ? 427 TRP B N     1 
ATOM   7385  C CA    . TRP B 1 427 ? -25.277 18.736  -47.419  1.00 46.85  ? 427 TRP B CA    1 
ATOM   7386  C C     . TRP B 1 427 ? -26.643 18.439  -46.808  1.00 43.15  ? 427 TRP B C     1 
ATOM   7387  O O     . TRP B 1 427 ? -27.537 19.278  -46.864  1.00 46.38  ? 427 TRP B O     1 
ATOM   7388  C CB    . TRP B 1 427 ? -24.846 17.708  -48.475  1.00 50.58  ? 427 TRP B CB    1 
ATOM   7389  C CG    . TRP B 1 427 ? -25.649 17.772  -49.732  1.00 47.01  ? 427 TRP B CG    1 
ATOM   7390  C CD1   . TRP B 1 427 ? -26.737 18.564  -49.982  1.00 47.97  ? 427 TRP B CD1   1 
ATOM   7391  C CD2   . TRP B 1 427 ? -25.421 17.003  -50.917  1.00 45.01  ? 427 TRP B CD2   1 
ATOM   7392  N NE1   . TRP B 1 427 ? -27.205 18.333  -51.249  1.00 49.17  ? 427 TRP B NE1   1 
ATOM   7393  C CE2   . TRP B 1 427 ? -26.416 17.377  -51.845  1.00 49.11  ? 427 TRP B CE2   1 
ATOM   7394  C CE3   . TRP B 1 427 ? -24.503 16.015  -51.272  1.00 48.98  ? 427 TRP B CE3   1 
ATOM   7395  C CZ2   . TRP B 1 427 ? -26.492 16.811  -53.115  1.00 47.12  ? 427 TRP B CZ2   1 
ATOM   7396  C CZ3   . TRP B 1 427 ? -24.589 15.447  -52.524  1.00 46.33  ? 427 TRP B CZ3   1 
ATOM   7397  C CH2   . TRP B 1 427 ? -25.567 15.845  -53.430  1.00 47.76  ? 427 TRP B CH2   1 
ATOM   7398  N N     . ARG B 1 428 ? -26.766 17.257  -46.191  1.00 43.61  ? 428 ARG B N     1 
ATOM   7399  C CA    . ARG B 1 428 ? -27.995 16.795  -45.565  1.00 43.88  ? 428 ARG B CA    1 
ATOM   7400  C C     . ARG B 1 428 ? -27.816 16.613  -44.055  1.00 41.07  ? 428 ARG B C     1 
ATOM   7401  O O     . ARG B 1 428 ? -28.790 16.338  -43.345  1.00 36.63  ? 428 ARG B O     1 
ATOM   7402  C CB    . ARG B 1 428 ? -28.407 15.470  -46.219  1.00 44.03  ? 428 ARG B CB    1 
ATOM   7403  C CG    . ARG B 1 428 ? -29.192 15.622  -47.517  1.00 45.68  ? 428 ARG B CG    1 
ATOM   7404  C CD    . ARG B 1 428 ? -29.444 14.282  -48.202  1.00 43.16  ? 428 ARG B CD    1 
ATOM   7405  N NE    . ARG B 1 428 ? -30.329 14.389  -49.352  1.00 40.92  ? 428 ARG B NE    1 
ATOM   7406  C CZ    . ARG B 1 428 ? -29.959 14.779  -50.569  1.00 43.61  ? 428 ARG B CZ    1 
ATOM   7407  N NH1   . ARG B 1 428 ? -28.709 15.104  -50.838  1.00 44.62  ? 428 ARG B NH1   1 
ATOM   7408  N NH2   . ARG B 1 428 ? -30.856 14.880  -51.528  1.00 49.79  ? 428 ARG B NH2   1 
ATOM   7409  N N     . ASP B 1 429 ? -26.573 16.769  -43.577  1.00 36.97  ? 429 ASP B N     1 
ATOM   7410  C CA    . ASP B 1 429 ? -26.179 16.451  -42.208  1.00 39.53  ? 429 ASP B CA    1 
ATOM   7411  C C     . ASP B 1 429 ? -26.021 17.731  -41.361  1.00 46.10  ? 429 ASP B C     1 
ATOM   7412  O O     . ASP B 1 429 ? -25.307 18.645  -41.759  1.00 47.92  ? 429 ASP B O     1 
ATOM   7413  C CB    . ASP B 1 429 ? -24.877 15.647  -42.257  1.00 41.78  ? 429 ASP B CB    1 
ATOM   7414  C CG    . ASP B 1 429 ? -23.720 16.272  -43.041  1.00 44.62  ? 429 ASP B CG    1 
ATOM   7415  O OD1   . ASP B 1 429 ? -23.936 16.772  -44.150  1.00 41.58  ? 429 ASP B OD1   1 
ATOM   7416  O OD2   . ASP B 1 429 ? -22.579 16.185  -42.567  1.00 53.76  ? 429 ASP B OD2   1 
ATOM   7417  N N     . LEU B 1 430 ? -26.686 17.816  -40.192  1.00 46.36  ? 430 LEU B N     1 
ATOM   7418  C CA    . LEU B 1 430 ? -26.443 18.881  -39.215  1.00 41.72  ? 430 LEU B CA    1 
ATOM   7419  C C     . LEU B 1 430 ? -25.413 18.404  -38.191  1.00 38.56  ? 430 LEU B C     1 
ATOM   7420  O O     . LEU B 1 430 ? -25.461 17.273  -37.754  1.00 35.79  ? 430 LEU B O     1 
ATOM   7421  C CB    . LEU B 1 430 ? -27.754 19.297  -38.527  1.00 37.45  ? 430 LEU B CB    1 
ATOM   7422  C CG    . LEU B 1 430 ? -27.629 20.380  -37.449  1.00 43.90  ? 430 LEU B CG    1 
ATOM   7423  C CD1   . LEU B 1 430 ? -27.325 21.735  -38.060  1.00 42.46  ? 430 LEU B CD1   1 
ATOM   7424  C CD2   . LEU B 1 430 ? -28.880 20.494  -36.574  1.00 40.98  ? 430 LEU B CD2   1 
ATOM   7425  N N     . HIS B 1 431 ? -24.470 19.277  -37.819  1.00 39.28  ? 431 HIS B N     1 
ATOM   7426  C CA    . HIS B 1 431 ? -23.593 19.038  -36.684  1.00 39.88  ? 431 HIS B CA    1 
ATOM   7427  C C     . HIS B 1 431 ? -23.620 20.225  -35.740  1.00 40.78  ? 431 HIS B C     1 
ATOM   7428  O O     . HIS B 1 431 ? -23.305 21.334  -36.167  1.00 39.67  ? 431 HIS B O     1 
ATOM   7429  C CB    . HIS B 1 431 ? -22.120 18.929  -37.090  1.00 38.54  ? 431 HIS B CB    1 
ATOM   7430  C CG    . HIS B 1 431 ? -21.831 17.855  -38.079  1.00 41.24  ? 431 HIS B CG    1 
ATOM   7431  N ND1   . HIS B 1 431 ? -22.223 17.918  -39.401  1.00 45.15  ? 431 HIS B ND1   1 
ATOM   7432  C CD2   . HIS B 1 431 ? -21.138 16.727  -37.954  1.00 43.33  ? 431 HIS B CD2   1 
ATOM   7433  C CE1   . HIS B 1 431 ? -21.746 16.879  -40.052  1.00 40.28  ? 431 HIS B CE1   1 
ATOM   7434  N NE2   . HIS B 1 431 ? -21.083 16.146  -39.195  1.00 45.93  ? 431 HIS B NE2   1 
ATOM   7435  N N     . HIS B 1 432 ? -23.957 19.968  -34.466  1.00 41.37  ? 432 HIS B N     1 
ATOM   7436  C CA    . HIS B 1 432 ? -23.756 20.937  -33.403  1.00 36.13  ? 432 HIS B CA    1 
ATOM   7437  C C     . HIS B 1 432 ? -22.369 20.682  -32.817  1.00 39.75  ? 432 HIS B C     1 
ATOM   7438  O O     . HIS B 1 432 ? -22.176 19.737  -32.054  1.00 37.96  ? 432 HIS B O     1 
ATOM   7439  C CB    . HIS B 1 432 ? -24.850 20.836  -32.351  1.00 39.34  ? 432 HIS B CB    1 
ATOM   7440  C CG    . HIS B 1 432 ? -24.640 21.790  -31.239  1.00 42.92  ? 432 HIS B CG    1 
ATOM   7441  N ND1   . HIS B 1 432 ? -23.865 21.468  -30.160  1.00 38.73  ? 432 HIS B ND1   1 
ATOM   7442  C CD2   . HIS B 1 432 ? -24.999 23.076  -31.070  1.00 46.83  ? 432 HIS B CD2   1 
ATOM   7443  C CE1   . HIS B 1 432 ? -23.774 22.530  -29.369  1.00 43.80  ? 432 HIS B CE1   1 
ATOM   7444  N NE2   . HIS B 1 432 ? -24.440 23.526  -29.905  1.00 41.27  ? 432 HIS B NE2   1 
ATOM   7445  N N     . VAL B 1 433 ? -21.393 21.489  -33.271  1.00 41.95  ? 433 VAL B N     1 
ATOM   7446  C CA    . VAL B 1 433 ? -20.008 21.430  -32.824  1.00 37.96  ? 433 VAL B CA    1 
ATOM   7447  C C     . VAL B 1 433 ? -19.860 22.267  -31.547  1.00 42.00  ? 433 VAL B C     1 
ATOM   7448  O O     . VAL B 1 433 ? -20.105 23.471  -31.545  1.00 46.30  ? 433 VAL B O     1 
ATOM   7449  C CB    . VAL B 1 433 ? -19.046 21.958  -33.899  1.00 38.07  ? 433 VAL B CB    1 
ATOM   7450  C CG1   . VAL B 1 433 ? -17.602 21.777  -33.470  1.00 39.23  ? 433 VAL B CG1   1 
ATOM   7451  C CG2   . VAL B 1 433 ? -19.290 21.352  -35.276  1.00 39.87  ? 433 VAL B CG2   1 
ATOM   7452  N N     . THR B 1 434 ? -19.501 21.613  -30.444  1.00 41.90  ? 434 THR B N     1 
ATOM   7453  C CA    . THR B 1 434 ? -19.166 22.280  -29.204  1.00 39.60  ? 434 THR B CA    1 
ATOM   7454  C C     . THR B 1 434 ? -17.663 22.464  -29.154  1.00 40.34  ? 434 THR B C     1 
ATOM   7455  O O     . THR B 1 434 ? -16.932 21.502  -29.350  1.00 38.63  ? 434 THR B O     1 
ATOM   7456  C CB    . THR B 1 434 ? -19.510 21.393  -28.016  1.00 43.79  ? 434 THR B CB    1 
ATOM   7457  O OG1   . THR B 1 434 ? -20.912 21.145  -28.097  1.00 47.52  ? 434 THR B OG1   1 
ATOM   7458  C CG2   . THR B 1 434 ? -19.107 22.010  -26.696  1.00 44.98  ? 434 THR B CG2   1 
ATOM   7459  N N     . VAL B 1 435 ? -17.225 23.679  -28.829  1.00 42.26  ? 435 VAL B N     1 
ATOM   7460  C CA    . VAL B 1 435 ? -15.814 23.977  -28.648  1.00 40.49  ? 435 VAL B CA    1 
ATOM   7461  C C     . VAL B 1 435 ? -15.582 24.442  -27.215  1.00 40.11  ? 435 VAL B C     1 
ATOM   7462  O O     . VAL B 1 435 ? -16.271 25.349  -26.774  1.00 40.07  ? 435 VAL B O     1 
ATOM   7463  C CB    . VAL B 1 435 ? -15.401 25.053  -29.654  1.00 43.74  ? 435 VAL B CB    1 
ATOM   7464  C CG1   . VAL B 1 435 ? -13.943 25.447  -29.487  1.00 45.92  ? 435 VAL B CG1   1 
ATOM   7465  C CG2   . VAL B 1 435 ? -15.717 24.597  -31.076  1.00 44.38  ? 435 VAL B CG2   1 
ATOM   7466  N N     . ILE B 1 436 ? -14.657 23.785  -26.502  1.00 39.66  ? 436 ILE B N     1 
ATOM   7467  C CA    . ILE B 1 436 ? -14.369 24.083  -25.104  1.00 39.96  ? 436 ILE B CA    1 
ATOM   7468  C C     . ILE B 1 436 ? -12.877 24.376  -24.981  1.00 48.79  ? 436 ILE B C     1 
ATOM   7469  O O     . ILE B 1 436 ? -12.036 23.522  -25.288  1.00 48.41  ? 436 ILE B O     1 
ATOM   7470  C CB    . ILE B 1 436 ? -14.704 22.931  -24.134  1.00 41.95  ? 436 ILE B CB    1 
ATOM   7471  C CG1   . ILE B 1 436 ? -16.095 22.334  -24.339  1.00 48.87  ? 436 ILE B CG1   1 
ATOM   7472  C CG2   . ILE B 1 436 ? -14.523 23.380  -22.702  1.00 41.96  ? 436 ILE B CG2   1 
ATOM   7473  C CD1   . ILE B 1 436 ? -16.192 20.901  -23.856  1.00 50.40  ? 436 ILE B CD1   1 
ATOM   7474  N N     . VAL B 1 437 ? -12.594 25.560  -24.431  1.00 47.09  ? 437 VAL B N     1 
ATOM   7475  C CA    . VAL B 1 437 ? -11.258 26.064  -24.220  1.00 46.60  ? 437 VAL B CA    1 
ATOM   7476  C C     . VAL B 1 437 ? -10.936 25.984  -22.721  1.00 42.49  ? 437 VAL B C     1 
ATOM   7477  O O     . VAL B 1 437 ? -11.715 26.414  -21.886  1.00 37.67  ? 437 VAL B O     1 
ATOM   7478  C CB    . VAL B 1 437 ? -11.193 27.491  -24.794  1.00 50.42  ? 437 VAL B CB    1 
ATOM   7479  C CG1   . VAL B 1 437 ? -9.984  28.266  -24.312  1.00 57.99  ? 437 VAL B CG1   1 
ATOM   7480  C CG2   . VAL B 1 437 ? -11.230 27.451  -26.312  1.00 52.55  ? 437 VAL B CG2   1 
ATOM   7481  N N     . TYR B 1 438 ? -9.761  25.443  -22.393  1.00 41.14  ? 438 TYR B N     1 
ATOM   7482  C CA    . TYR B 1 438 ? -9.436  25.038  -21.037  1.00 45.91  ? 438 TYR B CA    1 
ATOM   7483  C C     . TYR B 1 438 ? -7.931  25.219  -20.790  1.00 48.46  ? 438 TYR B C     1 
ATOM   7484  O O     . TYR B 1 438 ? -7.099  25.073  -21.705  1.00 45.25  ? 438 TYR B O     1 
ATOM   7485  C CB    . TYR B 1 438 ? -9.905  23.583  -20.813  1.00 46.82  ? 438 TYR B CB    1 
ATOM   7486  C CG    . TYR B 1 438 ? -9.237  22.525  -21.665  1.00 46.89  ? 438 TYR B CG    1 
ATOM   7487  C CD1   . TYR B 1 438 ? -9.556  22.374  -23.006  1.00 51.73  ? 438 TYR B CD1   1 
ATOM   7488  C CD2   . TYR B 1 438 ? -8.260  21.683  -21.150  1.00 49.46  ? 438 TYR B CD2   1 
ATOM   7489  C CE1   . TYR B 1 438 ? -8.940  21.419  -23.803  1.00 54.47  ? 438 TYR B CE1   1 
ATOM   7490  C CE2   . TYR B 1 438 ? -7.624  20.726  -21.940  1.00 52.84  ? 438 TYR B CE2   1 
ATOM   7491  C CZ    . TYR B 1 438 ? -7.963  20.593  -23.277  1.00 57.86  ? 438 TYR B CZ    1 
ATOM   7492  O OH    . TYR B 1 438 ? -7.359  19.668  -24.109  1.00 67.17  ? 438 TYR B OH    1 
ATOM   7493  N N     . ASP B 1 439 ? -7.580  25.481  -19.527  1.00 48.49  ? 439 ASP B N     1 
ATOM   7494  C CA    . ASP B 1 439 ? -6.189  25.505  -19.111  1.00 49.50  ? 439 ASP B CA    1 
ATOM   7495  C C     . ASP B 1 439 ? -5.629  24.072  -19.090  1.00 52.32  ? 439 ASP B C     1 
ATOM   7496  O O     . ASP B 1 439 ? -5.830  23.325  -18.142  1.00 53.55  ? 439 ASP B O     1 
ATOM   7497  C CB    . ASP B 1 439 ? -6.083  26.241  -17.774  1.00 52.62  ? 439 ASP B CB    1 
ATOM   7498  C CG    . ASP B 1 439 ? -4.671  26.488  -17.248  1.00 60.08  ? 439 ASP B CG    1 
ATOM   7499  O OD1   . ASP B 1 439 ? -3.717  25.740  -17.634  1.00 51.54  ? 439 ASP B OD1   1 
ATOM   7500  O OD2   . ASP B 1 439 ? -4.533  27.444  -16.444  1.00 63.41  ? 439 ASP B OD2   1 
ATOM   7501  N N     . LYS B 1 440 ? -4.854  23.712  -20.117  1.00 58.48  ? 440 LYS B N     1 
ATOM   7502  C CA    . LYS B 1 440 ? -4.257  22.387  -20.244  1.00 63.45  ? 440 LYS B CA    1 
ATOM   7503  C C     . LYS B 1 440 ? -3.080  22.185  -19.287  1.00 61.99  ? 440 LYS B C     1 
ATOM   7504  O O     . LYS B 1 440 ? -2.476  21.118  -19.298  1.00 58.29  ? 440 LYS B O     1 
ATOM   7505  C CB    . LYS B 1 440 ? -3.755  22.165  -21.679  1.00 70.21  ? 440 LYS B CB    1 
ATOM   7506  C CG    . LYS B 1 440 ? -2.990  23.348  -22.257  1.00 83.51  ? 440 LYS B CG    1 
ATOM   7507  C CD    . LYS B 1 440 ? -1.815  22.986  -23.127  1.00 94.85  ? 440 LYS B CD    1 
ATOM   7508  C CE    . LYS B 1 440 ? -0.948  24.187  -23.441  1.00 95.57  ? 440 LYS B CE    1 
ATOM   7509  N NZ    . LYS B 1 440 ? 0.302   23.762  -24.101  1.00 96.97  ? 440 LYS B NZ    1 
ATOM   7510  N N     . THR B 1 441 ? -2.741  23.191  -18.468  1.00 70.34  ? 441 THR B N     1 
ATOM   7511  C CA    . THR B 1 441 ? -1.649  23.076  -17.503  1.00 68.43  ? 441 THR B CA    1 
ATOM   7512  C C     . THR B 1 441 ? -2.178  22.837  -16.082  1.00 63.43  ? 441 THR B C     1 
ATOM   7513  O O     . THR B 1 441 ? -1.406  22.526  -15.186  1.00 61.28  ? 441 THR B O     1 
ATOM   7514  C CB    . THR B 1 441 ? -0.764  24.332  -17.524  1.00 56.14  ? 441 THR B CB    1 
ATOM   7515  O OG1   . THR B 1 441 ? -1.347  25.359  -16.721  1.00 48.95  ? 441 THR B OG1   1 
ATOM   7516  C CG2   . THR B 1 441 ? -0.539  24.863  -18.921  1.00 55.25  ? 441 THR B CG2   1 
ATOM   7517  N N     . ASP B 1 442 ? -3.488  23.012  -15.877  1.00 65.13  ? 442 ASP B N     1 
ATOM   7518  C CA    . ASP B 1 442 ? -4.104  22.934  -14.560  1.00 64.84  ? 442 ASP B CA    1 
ATOM   7519  C C     . ASP B 1 442 ? -4.842  21.601  -14.426  1.00 66.26  ? 442 ASP B C     1 
ATOM   7520  O O     . ASP B 1 442 ? -5.882  21.401  -15.049  1.00 62.88  ? 442 ASP B O     1 
ATOM   7521  C CB    . ASP B 1 442 ? -5.034  24.133  -14.356  1.00 58.27  ? 442 ASP B CB    1 
ATOM   7522  C CG    . ASP B 1 442 ? -5.706  24.172  -12.993  1.00 61.31  ? 442 ASP B CG    1 
ATOM   7523  O OD1   . ASP B 1 442 ? -5.467  23.248  -12.197  1.00 73.44  ? 442 ASP B OD1   1 
ATOM   7524  O OD2   . ASP B 1 442 ? -6.472  25.120  -12.742  1.00 57.41  ? 442 ASP B OD2   1 
ATOM   7525  N N     . PRO B 1 443 ? -4.335  20.643  -13.620  1.00 66.18  ? 443 PRO B N     1 
ATOM   7526  C CA    . PRO B 1 443 ? -4.983  19.334  -13.457  1.00 65.67  ? 443 PRO B CA    1 
ATOM   7527  C C     . PRO B 1 443 ? -6.431  19.303  -12.939  1.00 63.64  ? 443 PRO B C     1 
ATOM   7528  O O     . PRO B 1 443 ? -7.205  18.416  -13.303  1.00 58.90  ? 443 PRO B O     1 
ATOM   7529  C CB    . PRO B 1 443 ? -4.047  18.623  -12.459  1.00 60.34  ? 443 PRO B CB    1 
ATOM   7530  C CG    . PRO B 1 443 ? -2.710  19.281  -12.680  1.00 61.69  ? 443 PRO B CG    1 
ATOM   7531  C CD    . PRO B 1 443 ? -3.065  20.737  -12.891  1.00 62.48  ? 443 PRO B CD    1 
ATOM   7532  N N     . ASP B 1 444 ? -6.800  20.243  -12.063  1.00 54.87  ? 444 ASP B N     1 
ATOM   7533  C CA    . ASP B 1 444 ? -8.175  20.339  -11.608  1.00 57.91  ? 444 ASP B CA    1 
ATOM   7534  C C     . ASP B 1 444 ? -9.086  20.700  -12.777  1.00 55.79  ? 444 ASP B C     1 
ATOM   7535  O O     . ASP B 1 444 ? -10.225 20.256  -12.814  1.00 62.95  ? 444 ASP B O     1 
ATOM   7536  C CB    . ASP B 1 444 ? -8.361  21.383  -10.496  1.00 69.18  ? 444 ASP B CB    1 
ATOM   7537  C CG    . ASP B 1 444 ? -7.760  20.997  -9.154   1.00 76.80  ? 444 ASP B CG    1 
ATOM   7538  O OD1   . ASP B 1 444 ? -6.527  20.819  -9.105   1.00 85.33  ? 444 ASP B OD1   1 
ATOM   7539  O OD2   . ASP B 1 444 ? -8.523  20.890  -8.166   1.00 82.75  ? 444 ASP B OD2   1 
ATOM   7540  N N     . GLU B 1 445 ? -8.603  21.572  -13.673  1.00 55.87  ? 445 GLU B N     1 
ATOM   7541  C CA    . GLU B 1 445 ? -9.359  22.050  -14.819  1.00 51.74  ? 445 GLU B CA    1 
ATOM   7542  C C     . GLU B 1 445 ? -9.443  20.937  -15.861  1.00 48.00  ? 445 GLU B C     1 
ATOM   7543  O O     . GLU B 1 445 ? -10.502 20.716  -16.434  1.00 42.69  ? 445 GLU B O     1 
ATOM   7544  C CB    . GLU B 1 445 ? -8.708  23.307  -15.390  1.00 56.16  ? 445 GLU B CB    1 
ATOM   7545  C CG    . GLU B 1 445 ? -9.404  23.899  -16.611  1.00 64.70  ? 445 GLU B CG    1 
ATOM   7546  C CD    . GLU B 1 445 ? -10.120 25.231  -16.426  1.00 68.35  ? 445 GLU B CD    1 
ATOM   7547  O OE1   . GLU B 1 445 ? -10.012 26.108  -17.352  1.00 53.43  ? 445 GLU B OE1   1 
ATOM   7548  O OE2   . GLU B 1 445 ? -10.788 25.386  -15.365  1.00 62.94  ? 445 GLU B OE2   1 
ATOM   7549  N N     . ARG B 1 446 ? -8.336  20.222  -16.059  1.00 44.15  ? 446 ARG B N     1 
ATOM   7550  C CA    . ARG B 1 446 ? -8.299  19.057  -16.934  1.00 53.04  ? 446 ARG B CA    1 
ATOM   7551  C C     . ARG B 1 446 ? -9.321  18.002  -16.511  1.00 54.68  ? 446 ARG B C     1 
ATOM   7552  O O     . ARG B 1 446 ? -9.854  17.285  -17.351  1.00 57.98  ? 446 ARG B O     1 
ATOM   7553  C CB    . ARG B 1 446 ? -6.911  18.395  -16.950  1.00 55.57  ? 446 ARG B CB    1 
ATOM   7554  C CG    . ARG B 1 446 ? -5.849  19.176  -17.717  1.00 59.10  ? 446 ARG B CG    1 
ATOM   7555  C CD    . ARG B 1 446 ? -4.706  18.291  -18.192  1.00 63.68  ? 446 ARG B CD    1 
ATOM   7556  N NE    . ARG B 1 446 ? -3.949  17.807  -17.058  1.00 75.21  ? 446 ARG B NE    1 
ATOM   7557  C CZ    . ARG B 1 446 ? -2.742  18.240  -16.696  1.00 80.96  ? 446 ARG B CZ    1 
ATOM   7558  N NH1   . ARG B 1 446 ? -2.041  19.034  -17.488  1.00 77.68  ? 446 ARG B NH1   1 
ATOM   7559  N NH2   . ARG B 1 446 ? -2.225  17.840  -15.547  1.00 76.40  ? 446 ARG B NH2   1 
ATOM   7560  N N     . LYS B 1 447 ? -9.543  17.860  -15.206  1.00 58.02  ? 447 LYS B N     1 
ATOM   7561  C CA    . LYS B 1 447 ? -10.445 16.841  -14.706  1.00 62.91  ? 447 LYS B CA    1 
ATOM   7562  C C     . LYS B 1 447 ? -11.881 17.242  -15.067  1.00 54.96  ? 447 LYS B C     1 
ATOM   7563  O O     . LYS B 1 447 ? -12.650 16.459  -15.600  1.00 58.66  ? 447 LYS B O     1 
ATOM   7564  C CB    . LYS B 1 447 ? -10.177 16.633  -13.207  1.00 63.66  ? 447 LYS B CB    1 
ATOM   7565  C CG    . LYS B 1 447 ? -11.090 15.648  -12.489  1.00 62.51  ? 447 LYS B CG    1 
ATOM   7566  C CD    . LYS B 1 447 ? -10.920 14.216  -12.949  1.00 75.19  ? 447 LYS B CD    1 
ATOM   7567  C CE    . LYS B 1 447 ? -11.844 13.232  -12.253  1.00 75.24  ? 447 LYS B CE    1 
ATOM   7568  N NZ    . LYS B 1 447 ? -13.226 13.326  -12.773  1.00 79.14  ? 447 LYS B NZ    1 
ATOM   7569  N N     . LYS B 1 448 ? -12.243 18.480  -14.776  1.00 52.86  ? 448 LYS B N     1 
ATOM   7570  C CA    . LYS B 1 448 ? -13.552 19.002  -15.126  1.00 56.36  ? 448 LYS B CA    1 
ATOM   7571  C C     . LYS B 1 448 ? -13.843 18.805  -16.614  1.00 50.52  ? 448 LYS B C     1 
ATOM   7572  O O     . LYS B 1 448 ? -14.946 18.420  -16.970  1.00 54.32  ? 448 LYS B O     1 
ATOM   7573  C CB    . LYS B 1 448 ? -13.634 20.497  -14.794  1.00 54.40  ? 448 LYS B CB    1 
ATOM   7574  C CG    . LYS B 1 448 ? -13.540 20.841  -13.311  1.00 55.48  ? 448 LYS B CG    1 
ATOM   7575  C CD    . LYS B 1 448 ? -13.311 22.322  -13.019  1.00 57.18  ? 448 LYS B CD    1 
ATOM   7576  C CE    . LYS B 1 448 ? -14.239 23.246  -13.783  1.00 54.80  ? 448 LYS B CE    1 
ATOM   7577  N NZ    . LYS B 1 448 ? -13.912 24.671  -13.553  1.00 56.40  ? 448 LYS B NZ    1 
ATOM   7578  N N     . LEU B 1 449 ? -12.882 19.120  -17.481  1.00 44.90  ? 449 LEU B N     1 
ATOM   7579  C CA    . LEU B 1 449 ? -13.112 19.008  -18.904  1.00 46.49  ? 449 LEU B CA    1 
ATOM   7580  C C     . LEU B 1 449 ? -13.384 17.551  -19.264  1.00 48.12  ? 449 LEU B C     1 
ATOM   7581  O O     . LEU B 1 449 ? -14.330 17.239  -19.978  1.00 50.10  ? 449 LEU B O     1 
ATOM   7582  C CB    . LEU B 1 449 ? -11.897 19.488  -19.699  1.00 45.22  ? 449 LEU B CB    1 
ATOM   7583  C CG    . LEU B 1 449 ? -12.094 19.329  -21.206  1.00 48.98  ? 449 LEU B CG    1 
ATOM   7584  C CD1   . LEU B 1 449 ? -12.815 20.523  -21.798  1.00 49.96  ? 449 LEU B CD1   1 
ATOM   7585  C CD2   . LEU B 1 449 ? -10.793 19.094  -21.911  1.00 54.57  ? 449 LEU B CD2   1 
ATOM   7586  N N     . ASP B 1 450 ? -12.516 16.665  -18.796  1.00 44.10  ? 450 ASP B N     1 
ATOM   7587  C CA    . ASP B 1 450 ? -12.584 15.259  -19.150  1.00 47.76  ? 450 ASP B CA    1 
ATOM   7588  C C     . ASP B 1 450 ? -13.979 14.707  -18.816  1.00 48.37  ? 450 ASP B C     1 
ATOM   7589  O O     . ASP B 1 450 ? -14.601 13.962  -19.586  1.00 41.76  ? 450 ASP B O     1 
ATOM   7590  C CB    . ASP B 1 450 ? -11.444 14.514  -18.449  1.00 50.80  ? 450 ASP B CB    1 
ATOM   7591  C CG    . ASP B 1 450 ? -11.289 13.074  -18.884  1.00 59.68  ? 450 ASP B CG    1 
ATOM   7592  O OD1   . ASP B 1 450 ? -11.736 12.745  -20.006  1.00 63.69  ? 450 ASP B OD1   1 
ATOM   7593  O OD2   . ASP B 1 450 ? -10.723 12.296  -18.092  1.00 72.47  ? 450 ASP B OD2   1 
ATOM   7594  N N     . GLU B 1 451 ? -14.471 15.121  -17.650  1.00 42.15  ? 451 GLU B N     1 
ATOM   7595  C CA    . GLU B 1 451 ? -15.731 14.655  -17.123  1.00 40.16  ? 451 GLU B CA    1 
ATOM   7596  C C     . GLU B 1 451 ? -16.858 15.226  -17.960  1.00 39.50  ? 451 GLU B C     1 
ATOM   7597  O O     . GLU B 1 451 ? -17.799 14.524  -18.284  1.00 42.32  ? 451 GLU B O     1 
ATOM   7598  C CB    . GLU B 1 451 ? -15.845 15.077  -15.660  1.00 39.56  ? 451 GLU B CB    1 
ATOM   7599  C CG    . GLU B 1 451 ? -17.178 14.774  -15.065  1.00 39.20  ? 451 GLU B CG    1 
ATOM   7600  C CD    . GLU B 1 451 ? -17.333 15.312  -13.655  1.00 51.56  ? 451 GLU B CD    1 
ATOM   7601  O OE1   . GLU B 1 451 ? -16.577 14.812  -12.744  1.00 45.64  ? 451 GLU B OE1   1 
ATOM   7602  O OE2   . GLU B 1 451 ? -18.223 16.218  -13.465  1.00 47.76  ? 451 GLU B OE2   1 
ATOM   7603  N N     . LEU B 1 452 ? -16.766 16.524  -18.255  1.00 44.02  ? 452 LEU B N     1 
ATOM   7604  C CA    . LEU B 1 452 ? -17.799 17.237  -18.981  1.00 38.42  ? 452 LEU B CA    1 
ATOM   7605  C C     . LEU B 1 452 ? -17.915 16.635  -20.375  1.00 41.01  ? 452 LEU B C     1 
ATOM   7606  O O     . LEU B 1 452 ? -19.015 16.409  -20.872  1.00 43.38  ? 452 LEU B O     1 
ATOM   7607  C CB    . LEU B 1 452 ? -17.392 18.704  -19.030  1.00 37.09  ? 452 LEU B CB    1 
ATOM   7608  C CG    . LEU B 1 452 ? -18.123 19.559  -20.052  1.00 38.17  ? 452 LEU B CG    1 
ATOM   7609  C CD1   . LEU B 1 452 ? -19.590 19.665  -19.731  1.00 37.66  ? 452 LEU B CD1   1 
ATOM   7610  C CD2   . LEU B 1 452 ? -17.498 20.931  -20.115  1.00 38.43  ? 452 LEU B CD2   1 
ATOM   7611  N N     . PHE B 1 453 ? -16.763 16.313  -20.969  1.00 41.46  ? 453 PHE B N     1 
ATOM   7612  C CA    . PHE B 1 453 ? -16.732 15.688  -22.279  1.00 43.77  ? 453 PHE B CA    1 
ATOM   7613  C C     . PHE B 1 453 ? -17.546 14.395  -22.272  1.00 48.75  ? 453 PHE B C     1 
ATOM   7614  O O     . PHE B 1 453 ? -18.350 14.178  -23.187  1.00 43.52  ? 453 PHE B O     1 
ATOM   7615  C CB    . PHE B 1 453 ? -15.307 15.355  -22.725  1.00 41.79  ? 453 PHE B CB    1 
ATOM   7616  C CG    . PHE B 1 453 ? -15.250 14.948  -24.171  1.00 42.45  ? 453 PHE B CG    1 
ATOM   7617  C CD1   . PHE B 1 453 ? -15.335 15.901  -25.180  1.00 43.29  ? 453 PHE B CD1   1 
ATOM   7618  C CD2   . PHE B 1 453 ? -15.190 13.607  -24.528  1.00 44.57  ? 453 PHE B CD2   1 
ATOM   7619  C CE1   . PHE B 1 453 ? -15.322 15.514  -26.512  1.00 42.62  ? 453 PHE B CE1   1 
ATOM   7620  C CE2   . PHE B 1 453 ? -15.199 13.224  -25.867  1.00 44.55  ? 453 PHE B CE2   1 
ATOM   7621  C CZ    . PHE B 1 453 ? -15.250 14.180  -26.855  1.00 38.70  ? 453 PHE B CZ    1 
ATOM   7622  N N     . ASN B 1 454 ? -17.297 13.548  -21.250  1.00 44.81  ? 454 ASN B N     1 
ATOM   7623  C CA    . ASN B 1 454 ? -17.893 12.221  -21.159  1.00 42.06  ? 454 ASN B CA    1 
ATOM   7624  C C     . ASN B 1 454 ? -19.418 12.344  -21.064  1.00 38.78  ? 454 ASN B C     1 
ATOM   7625  O O     . ASN B 1 454 ? -20.156 11.660  -21.762  1.00 45.97  ? 454 ASN B O     1 
ATOM   7626  C CB    . ASN B 1 454 ? -17.262 11.390  -20.037  1.00 41.08  ? 454 ASN B CB    1 
ATOM   7627  C CG    . ASN B 1 454 ? -15.959 10.718  -20.434  1.00 42.01  ? 454 ASN B CG    1 
ATOM   7628  O OD1   . ASN B 1 454 ? -15.908 9.854   -21.306  1.00 59.04  ? 454 ASN B OD1   1 
ATOM   7629  N ND2   . ASN B 1 454 ? -14.876 11.101  -19.806  1.00 49.02  ? 454 ASN B ND2   1 
ATOM   7630  N N     . ILE B 1 455 ? -19.887 13.322  -20.321  1.00 34.39  ? 455 ILE B N     1 
ATOM   7631  C CA    . ILE B 1 455 ? -21.309 13.506  -20.131  1.00 35.09  ? 455 ILE B CA    1 
ATOM   7632  C C     . ILE B 1 455 ? -21.940 14.010  -21.427  1.00 34.17  ? 455 ILE B C     1 
ATOM   7633  O O     . ILE B 1 455 ? -23.071 13.657  -21.759  1.00 34.18  ? 455 ILE B O     1 
ATOM   7634  C CB    . ILE B 1 455 ? -21.546 14.425  -18.903  1.00 34.26  ? 455 ILE B CB    1 
ATOM   7635  C CG1   . ILE B 1 455 ? -21.079 13.735  -17.618  1.00 33.37  ? 455 ILE B CG1   1 
ATOM   7636  C CG2   . ILE B 1 455 ? -22.995 14.889  -18.773  1.00 37.18  ? 455 ILE B CG2   1 
ATOM   7637  C CD1   . ILE B 1 455 ? -21.392 14.466  -16.325  1.00 33.35  ? 455 ILE B CD1   1 
ATOM   7638  N N     . LEU B 1 456 ? -21.241 14.867  -22.167  1.00 40.20  ? 456 LEU B N     1 
ATOM   7639  C CA    . LEU B 1 456 ? -21.811 15.393  -23.404  1.00 36.64  ? 456 LEU B CA    1 
ATOM   7640  C C     . LEU B 1 456 ? -21.959 14.247  -24.407  1.00 36.67  ? 456 LEU B C     1 
ATOM   7641  O O     . LEU B 1 456 ? -23.010 14.081  -25.032  1.00 45.89  ? 456 LEU B O     1 
ATOM   7642  C CB    . LEU B 1 456 ? -20.918 16.507  -23.961  1.00 40.62  ? 456 LEU B CB    1 
ATOM   7643  C CG    . LEU B 1 456 ? -20.847 17.817  -23.167  1.00 38.63  ? 456 LEU B CG    1 
ATOM   7644  C CD1   . LEU B 1 456 ? -19.764 18.732  -23.746  1.00 36.25  ? 456 LEU B CD1   1 
ATOM   7645  C CD2   . LEU B 1 456 ? -22.171 18.535  -23.139  1.00 29.00  ? 456 LEU B CD2   1 
ATOM   7646  N N     . VAL B 1 457 ? -20.935 13.406  -24.519  1.00 33.40  ? 457 VAL B N     1 
ATOM   7647  C CA    . VAL B 1 457 ? -20.983 12.280  -25.454  1.00 38.84  ? 457 VAL B CA    1 
ATOM   7648  C C     . VAL B 1 457 ? -22.135 11.346  -25.064  1.00 42.09  ? 457 VAL B C     1 
ATOM   7649  O O     . VAL B 1 457 ? -22.856 10.824  -25.921  1.00 40.03  ? 457 VAL B O     1 
ATOM   7650  C CB    . VAL B 1 457 ? -19.632 11.528  -25.542  1.00 32.90  ? 457 VAL B CB    1 
ATOM   7651  C CG1   . VAL B 1 457 ? -19.695 10.287  -26.385  1.00 31.31  ? 457 VAL B CG1   1 
ATOM   7652  C CG2   . VAL B 1 457 ? -18.499 12.407  -26.062  1.00 32.46  ? 457 VAL B CG2   1 
ATOM   7653  N N     . ASP B 1 458 ? -22.289 11.136  -23.753  1.00 42.73  ? 458 ASP B N     1 
ATOM   7654  C CA    . ASP B 1 458 ? -23.318 10.251  -23.239  1.00 40.03  ? 458 ASP B CA    1 
ATOM   7655  C C     . ASP B 1 458 ? -24.705 10.840  -23.514  1.00 41.94  ? 458 ASP B C     1 
ATOM   7656  O O     . ASP B 1 458 ? -25.571 10.184  -24.092  1.00 39.77  ? 458 ASP B O     1 
ATOM   7657  C CB    . ASP B 1 458 ? -23.106 9.991   -21.748  1.00 38.50  ? 458 ASP B CB    1 
ATOM   7658  C CG    . ASP B 1 458 ? -21.916 9.113   -21.386  1.00 35.27  ? 458 ASP B CG    1 
ATOM   7659  O OD1   . ASP B 1 458 ? -21.394 8.446   -22.285  1.00 31.31  ? 458 ASP B OD1   1 
ATOM   7660  O OD2   . ASP B 1 458 ? -21.511 9.119   -20.180  1.00 36.17  ? 458 ASP B OD2   1 
ATOM   7661  N N     . GLU B 1 459 ? -24.930 12.088  -23.099  1.00 45.08  ? 459 GLU B N     1 
ATOM   7662  C CA    . GLU B 1 459 ? -26.273 12.656  -23.180  1.00 46.65  ? 459 GLU B CA    1 
ATOM   7663  C C     . GLU B 1 459 ? -26.717 12.833  -24.646  1.00 41.96  ? 459 GLU B C     1 
ATOM   7664  O O     . GLU B 1 459 ? -27.891 12.680  -24.959  1.00 45.18  ? 459 GLU B O     1 
ATOM   7665  C CB    . GLU B 1 459 ? -26.337 13.925  -22.334  1.00 42.70  ? 459 GLU B CB    1 
ATOM   7666  C CG    . GLU B 1 459 ? -26.060 13.661  -20.861  1.00 46.30  ? 459 GLU B CG    1 
ATOM   7667  C CD    . GLU B 1 459 ? -26.351 14.759  -19.841  1.00 42.78  ? 459 GLU B CD    1 
ATOM   7668  O OE1   . GLU B 1 459 ? -26.394 15.963  -20.189  1.00 44.13  ? 459 GLU B OE1   1 
ATOM   7669  O OE2   . GLU B 1 459 ? -26.565 14.393  -18.689  1.00 43.93  ? 459 GLU B OE2   1 
ATOM   7670  N N     . ALA B 1 460 ? -25.771 13.072  -25.551  1.00 43.06  ? 460 ALA B N     1 
ATOM   7671  C CA    . ALA B 1 460 ? -26.041 13.260  -26.970  1.00 43.01  ? 460 ALA B CA    1 
ATOM   7672  C C     . ALA B 1 460 ? -26.259 11.913  -27.676  1.00 45.02  ? 460 ALA B C     1 
ATOM   7673  O O     . ALA B 1 460 ? -27.166 11.810  -28.495  1.00 43.19  ? 460 ALA B O     1 
ATOM   7674  C CB    . ALA B 1 460 ? -24.886 14.010  -27.595  1.00 41.12  ? 460 ALA B CB    1 
ATOM   7675  N N     . ALA B 1 461 ? -25.473 10.868  -27.348  1.00 36.53  ? 461 ALA B N     1 
ATOM   7676  C CA    . ALA B 1 461 ? -25.684 9.564   -27.967  1.00 36.43  ? 461 ALA B CA    1 
ATOM   7677  C C     . ALA B 1 461 ? -27.088 9.061   -27.688  1.00 36.42  ? 461 ALA B C     1 
ATOM   7678  O O     . ALA B 1 461 ? -27.804 8.661   -28.594  1.00 43.65  ? 461 ALA B O     1 
ATOM   7679  C CB    . ALA B 1 461 ? -24.666 8.575   -27.542  1.00 35.46  ? 461 ALA B CB    1 
ATOM   7680  N N     . ALA B 1 462 ? -27.527 9.257   -26.458  1.00 45.15  ? 462 ALA B N     1 
ATOM   7681  C CA    . ALA B 1 462 ? -28.841 8.826   -26.022  1.00 45.77  ? 462 ALA B CA    1 
ATOM   7682  C C     . ALA B 1 462 ? -29.952 9.556   -26.775  1.00 38.20  ? 462 ALA B C     1 
ATOM   7683  O O     . ALA B 1 462 ? -31.057 9.071   -26.780  1.00 39.40  ? 462 ALA B O     1 
ATOM   7684  C CB    . ALA B 1 462 ? -28.972 9.022   -24.533  1.00 42.14  ? 462 ALA B CB    1 
ATOM   7685  N N     . GLU B 1 463 ? -29.670 10.704  -27.387  1.00 39.84  ? 463 GLU B N     1 
ATOM   7686  C CA    . GLU B 1 463 ? -30.641 11.372  -28.232  1.00 37.54  ? 463 GLU B CA    1 
ATOM   7687  C C     . GLU B 1 463 ? -30.381 11.029  -29.691  1.00 35.08  ? 463 GLU B C     1 
ATOM   7688  O O     . GLU B 1 463 ? -30.890 11.680  -30.586  1.00 42.64  ? 463 GLU B O     1 
ATOM   7689  C CB    . GLU B 1 463 ? -30.549 12.884  -28.079  1.00 48.02  ? 463 GLU B CB    1 
ATOM   7690  C CG    . GLU B 1 463 ? -30.665 13.416  -26.654  1.00 51.23  ? 463 GLU B CG    1 
ATOM   7691  C CD    . GLU B 1 463 ? -32.022 13.250  -26.006  1.00 58.90  ? 463 GLU B CD    1 
ATOM   7692  O OE1   . GLU B 1 463 ? -33.059 13.518  -26.696  1.00 45.71  ? 463 GLU B OE1   1 
ATOM   7693  O OE2   . GLU B 1 463 ? -32.027 12.893  -24.794  1.00 66.34  ? 463 GLU B OE2   1 
ATOM   7694  N N     . GLY B 1 464 ? -29.524 10.048  -29.949  1.00 37.76  ? 464 GLY B N     1 
ATOM   7695  C CA    . GLY B 1 464 ? -29.291 9.633   -31.324  1.00 46.23  ? 464 GLY B CA    1 
ATOM   7696  C C     . GLY B 1 464 ? -28.247 10.458  -32.083  1.00 48.58  ? 464 GLY B C     1 
ATOM   7697  O O     . GLY B 1 464 ? -28.124 10.304  -33.303  1.00 52.45  ? 464 GLY B O     1 
ATOM   7698  N N     . TYR B 1 465 ? -27.473 11.289  -31.370  1.00 41.60  ? 465 TYR B N     1 
ATOM   7699  C CA    . TYR B 1 465 ? -26.418 12.059  -32.006  1.00 41.86  ? 465 TYR B CA    1 
ATOM   7700  C C     . TYR B 1 465 ? -25.046 11.453  -31.718  1.00 39.47  ? 465 TYR B C     1 
ATOM   7701  O O     . TYR B 1 465 ? -24.616 11.457  -30.559  1.00 40.02  ? 465 TYR B O     1 
ATOM   7702  C CB    . TYR B 1 465 ? -26.445 13.505  -31.528  1.00 42.83  ? 465 TYR B CB    1 
ATOM   7703  C CG    . TYR B 1 465 ? -27.809 14.130  -31.494  1.00 37.59  ? 465 TYR B CG    1 
ATOM   7704  C CD1   . TYR B 1 465 ? -28.714 13.962  -32.534  1.00 34.43  ? 465 TYR B CD1   1 
ATOM   7705  C CD2   . TYR B 1 465 ? -28.189 14.897  -30.406  1.00 31.96  ? 465 TYR B CD2   1 
ATOM   7706  C CE1   . TYR B 1 465 ? -29.973 14.557  -32.498  1.00 32.27  ? 465 TYR B CE1   1 
ATOM   7707  C CE2   . TYR B 1 465 ? -29.460 15.454  -30.339  1.00 36.73  ? 465 TYR B CE2   1 
ATOM   7708  C CZ    . TYR B 1 465 ? -30.351 15.305  -31.395  1.00 34.60  ? 465 TYR B CZ    1 
ATOM   7709  O OH    . TYR B 1 465 ? -31.574 15.943  -31.309  1.00 33.40  ? 465 TYR B OH    1 
ATOM   7710  N N     . GLY B 1 466 ? -24.373 10.994  -32.796  1.00 34.01  ? 466 GLY B N     1 
ATOM   7711  C CA    . GLY B 1 466 ? -23.083 10.318  -32.721  1.00 33.25  ? 466 GLY B CA    1 
ATOM   7712  C C     . GLY B 1 466 ? -21.925 11.047  -33.421  1.00 32.16  ? 466 GLY B C     1 
ATOM   7713  O O     . GLY B 1 466 ? -22.040 11.564  -34.522  1.00 33.27  ? 466 GLY B O     1 
ATOM   7714  N N     . GLU B 1 467 ? -20.746 10.970  -32.804  1.00 37.54  ? 467 GLU B N     1 
ATOM   7715  C CA    . GLU B 1 467 ? -19.551 11.687  -33.229  1.00 34.88  ? 467 GLU B CA    1 
ATOM   7716  C C     . GLU B 1 467 ? -18.982 11.015  -34.477  1.00 35.97  ? 467 GLU B C     1 
ATOM   7717  O O     . GLU B 1 467 ? -19.104 9.814   -34.631  1.00 42.12  ? 467 GLU B O     1 
ATOM   7718  C CB    . GLU B 1 467 ? -18.568 11.723  -32.050  1.00 33.67  ? 467 GLU B CB    1 
ATOM   7719  C CG    . GLU B 1 467 ? -17.270 12.468  -32.290  1.00 38.01  ? 467 GLU B CG    1 
ATOM   7720  C CD    . GLU B 1 467 ? -17.406 13.895  -32.811  1.00 43.17  ? 467 GLU B CD    1 
ATOM   7721  O OE1   . GLU B 1 467 ? -17.682 14.059  -34.037  1.00 41.31  ? 467 GLU B OE1   1 
ATOM   7722  O OE2   . GLU B 1 467 ? -17.282 14.847  -31.980  1.00 45.55  ? 467 GLU B OE2   1 
ATOM   7723  N N     . TYR B 1 468 ? -18.321 11.799  -35.341  1.00 41.69  ? 468 TYR B N     1 
ATOM   7724  C CA    . TYR B 1 468 ? -17.724 11.284  -36.564  1.00 42.76  ? 468 TYR B CA    1 
ATOM   7725  C C     . TYR B 1 468 ? -16.205 11.419  -36.530  1.00 46.47  ? 468 TYR B C     1 
ATOM   7726  O O     . TYR B 1 468 ? -15.520 10.818  -37.356  1.00 45.11  ? 468 TYR B O     1 
ATOM   7727  C CB    . TYR B 1 468 ? -18.317 11.976  -37.794  1.00 39.89  ? 468 TYR B CB    1 
ATOM   7728  C CG    . TYR B 1 468 ? -17.810 13.357  -38.121  1.00 42.49  ? 468 TYR B CG    1 
ATOM   7729  C CD1   . TYR B 1 468 ? -18.213 14.478  -37.409  1.00 47.90  ? 468 TYR B CD1   1 
ATOM   7730  C CD2   . TYR B 1 468 ? -16.956 13.555  -39.193  1.00 41.73  ? 468 TYR B CD2   1 
ATOM   7731  C CE1   . TYR B 1 468 ? -17.775 15.756  -37.743  1.00 49.83  ? 468 TYR B CE1   1 
ATOM   7732  C CE2   . TYR B 1 468 ? -16.499 14.815  -39.534  1.00 42.04  ? 468 TYR B CE2   1 
ATOM   7733  C CZ    . TYR B 1 468 ? -16.909 15.925  -38.813  1.00 50.55  ? 468 TYR B CZ    1 
ATOM   7734  O OH    . TYR B 1 468 ? -16.431 17.169  -39.180  1.00 45.74  ? 468 TYR B OH    1 
ATOM   7735  N N     . ARG B 1 469 ? -15.680 12.186  -35.569  1.00 49.13  ? 469 ARG B N     1 
ATOM   7736  C CA    . ARG B 1 469 ? -14.247 12.445  -35.514  1.00 49.75  ? 469 ARG B CA    1 
ATOM   7737  C C     . ARG B 1 469 ? -13.861 12.974  -34.140  1.00 42.74  ? 469 ARG B C     1 
ATOM   7738  O O     . ARG B 1 469 ? -14.566 13.826  -33.602  1.00 40.23  ? 469 ARG B O     1 
ATOM   7739  C CB    . ARG B 1 469 ? -13.916 13.515  -36.542  1.00 51.97  ? 469 ARG B CB    1 
ATOM   7740  C CG    . ARG B 1 469 ? -12.434 13.633  -36.831  1.00 59.26  ? 469 ARG B CG    1 
ATOM   7741  C CD    . ARG B 1 469 ? -12.203 14.851  -37.704  1.00 64.56  ? 469 ARG B CD    1 
ATOM   7742  N NE    . ARG B 1 469 ? -10.778 15.082  -37.873  1.00 68.71  ? 469 ARG B NE    1 
ATOM   7743  C CZ    . ARG B 1 469 ? -10.265 16.195  -38.364  1.00 56.42  ? 469 ARG B CZ    1 
ATOM   7744  N NH1   . ARG B 1 469 ? -11.082 17.124  -38.816  1.00 49.76  ? 469 ARG B NH1   1 
ATOM   7745  N NH2   . ARG B 1 469 ? -8.953  16.364  -38.381  1.00 60.68  ? 469 ARG B NH2   1 
ATOM   7746  N N     . THR B 1 470 ? -12.730 12.501  -33.613  1.00 43.04  ? 470 THR B N     1 
ATOM   7747  C CA    . THR B 1 470 ? -12.420 12.676  -32.202  1.00 48.20  ? 470 THR B CA    1 
ATOM   7748  C C     . THR B 1 470 ? -10.931 12.540  -31.890  1.00 49.50  ? 470 THR B C     1 
ATOM   7749  O O     . THR B 1 470 ? -10.145 12.084  -32.726  1.00 50.84  ? 470 THR B O     1 
ATOM   7750  C CB    . THR B 1 470 ? -13.192 11.662  -31.350  1.00 48.72  ? 470 THR B CB    1 
ATOM   7751  O OG1   . THR B 1 470 ? -13.341 12.206  -30.039  1.00 38.28  ? 470 THR B OG1   1 
ATOM   7752  C CG2   . THR B 1 470 ? -12.518 10.304  -31.322  1.00 48.68  ? 470 THR B CG2   1 
ATOM   7753  N N     . HIS B 1 471 ? -10.609 12.951  -30.644  1.00 51.73  ? 471 HIS B N     1 
ATOM   7754  C CA    . HIS B 1 471 ? -9.286  12.970  -30.022  1.00 46.25  ? 471 HIS B CA    1 
ATOM   7755  C C     . HIS B 1 471 ? -8.800  11.544  -29.765  1.00 44.32  ? 471 HIS B C     1 
ATOM   7756  O O     . HIS B 1 471 ? -9.600  10.701  -29.384  1.00 50.98  ? 471 HIS B O     1 
ATOM   7757  C CB    . HIS B 1 471 ? -9.401  13.768  -28.701  1.00 55.73  ? 471 HIS B CB    1 
ATOM   7758  C CG    . HIS B 1 471 ? -8.110  13.972  -27.967  1.00 61.38  ? 471 HIS B CG    1 
ATOM   7759  N ND1   . HIS B 1 471 ? -7.461  12.974  -27.270  1.00 60.02  ? 471 HIS B ND1   1 
ATOM   7760  C CD2   . HIS B 1 471 ? -7.309  15.057  -27.880  1.00 68.22  ? 471 HIS B CD2   1 
ATOM   7761  C CE1   . HIS B 1 471 ? -6.312  13.446  -26.797  1.00 65.44  ? 471 HIS B CE1   1 
ATOM   7762  N NE2   . HIS B 1 471 ? -6.194  14.700  -27.169  1.00 62.37  ? 471 HIS B NE2   1 
ATOM   7763  N N     . ILE B 1 472 ? -7.493  11.258  -29.923  1.00 48.15  ? 472 ILE B N     1 
ATOM   7764  C CA    . ILE B 1 472 ? -6.960  9.921   -29.636  1.00 45.39  ? 472 ILE B CA    1 
ATOM   7765  C C     . ILE B 1 472 ? -7.500  9.359   -28.323  1.00 47.74  ? 472 ILE B C     1 
ATOM   7766  O O     . ILE B 1 472 ? -7.775  8.157   -28.225  1.00 51.65  ? 472 ILE B O     1 
ATOM   7767  C CB    . ILE B 1 472 ? -5.418  9.873   -29.608  1.00 54.04  ? 472 ILE B CB    1 
ATOM   7768  C CG1   . ILE B 1 472 ? -4.809  10.933  -28.689  1.00 58.13  ? 472 ILE B CG1   1 
ATOM   7769  C CG2   . ILE B 1 472 ? -4.804  9.925   -31.009  1.00 48.53  ? 472 ILE B CG2   1 
ATOM   7770  C CD1   . ILE B 1 472 ? -3.309  10.756  -28.509  1.00 62.79  ? 472 ILE B CD1   1 
ATOM   7771  N N     . ARG B 1 473 ? -7.591  10.202  -27.288  1.00 50.89  ? 473 ARG B N     1 
ATOM   7772  C CA    . ARG B 1 473 ? -8.016  9.748   -25.969  1.00 56.60  ? 473 ARG B CA    1 
ATOM   7773  C C     . ARG B 1 473 ? -9.405  9.104   -25.998  1.00 54.01  ? 473 ARG B C     1 
ATOM   7774  O O     . ARG B 1 473 ? -9.725  8.293   -25.133  1.00 48.80  ? 473 ARG B O     1 
ATOM   7775  C CB    . ARG B 1 473 ? -8.060  10.935  -24.996  1.00 69.90  ? 473 ARG B CB    1 
ATOM   7776  C CG    . ARG B 1 473 ? -8.721  10.627  -23.651  1.00 76.81  ? 473 ARG B CG    1 
ATOM   7777  C CD    . ARG B 1 473 ? -8.485  11.715  -22.615  1.00 81.35  ? 473 ARG B CD    1 
ATOM   7778  N NE    . ARG B 1 473 ? -9.003  11.399  -21.289  1.00 75.51  ? 473 ARG B NE    1 
ATOM   7779  C CZ    . ARG B 1 473 ? -8.465  10.514  -20.463  1.00 70.61  ? 473 ARG B CZ    1 
ATOM   7780  N NH1   . ARG B 1 473 ? -7.434  9.788   -20.860  1.00 73.15  ? 473 ARG B NH1   1 
ATOM   7781  N NH2   . ARG B 1 473 ? -8.958  10.354  -19.247  1.00 61.82  ? 473 ARG B NH2   1 
ATOM   7782  N N     . TYR B 1 474 ? -10.256 9.503   -26.956  1.00 46.33  ? 474 TYR B N     1 
ATOM   7783  C CA    . TYR B 1 474 ? -11.667 9.182   -26.888  1.00 45.97  ? 474 TYR B CA    1 
ATOM   7784  C C     . TYR B 1 474 ? -12.072 8.221   -28.005  1.00 43.50  ? 474 TYR B C     1 
ATOM   7785  O O     . TYR B 1 474 ? -13.257 7.965   -28.213  1.00 48.37  ? 474 TYR B O     1 
ATOM   7786  C CB    . TYR B 1 474 ? -12.472 10.482  -26.946  1.00 45.22  ? 474 TYR B CB    1 
ATOM   7787  C CG    . TYR B 1 474 ? -12.237 11.410  -25.786  1.00 49.05  ? 474 TYR B CG    1 
ATOM   7788  C CD1   . TYR B 1 474 ? -12.401 10.962  -24.484  1.00 58.93  ? 474 TYR B CD1   1 
ATOM   7789  C CD2   . TYR B 1 474 ? -11.900 12.741  -25.976  1.00 53.17  ? 474 TYR B CD2   1 
ATOM   7790  C CE1   . TYR B 1 474 ? -12.207 11.801  -23.397  1.00 66.18  ? 474 TYR B CE1   1 
ATOM   7791  C CE2   . TYR B 1 474 ? -11.717 13.602  -24.899  1.00 59.01  ? 474 TYR B CE2   1 
ATOM   7792  C CZ    . TYR B 1 474 ? -11.867 13.131  -23.599  1.00 70.65  ? 474 TYR B CZ    1 
ATOM   7793  O OH    . TYR B 1 474 ? -11.694 13.944  -22.480  1.00 64.12  ? 474 TYR B OH    1 
ATOM   7794  N N     . MET B 1 475 ? -11.096 7.633   -28.684  1.00 37.72  ? 475 MET B N     1 
ATOM   7795  C CA    . MET B 1 475 ? -11.381 6.858   -29.877  1.00 39.20  ? 475 MET B CA    1 
ATOM   7796  C C     . MET B 1 475 ? -12.149 5.573   -29.562  1.00 42.23  ? 475 MET B C     1 
ATOM   7797  O O     . MET B 1 475 ? -12.962 5.162   -30.386  1.00 40.83  ? 475 MET B O     1 
ATOM   7798  C CB    . MET B 1 475 ? -10.082 6.490   -30.591  1.00 36.48  ? 475 MET B CB    1 
ATOM   7799  C CG    . MET B 1 475 ? -9.486  7.648   -31.290  1.00 37.73  ? 475 MET B CG    1 
ATOM   7800  S SD    . MET B 1 475 ? -8.057  7.193   -32.288  1.00 51.16  ? 475 MET B SD    1 
ATOM   7801  C CE    . MET B 1 475 ? -7.916  8.790   -33.102  1.00 49.36  ? 475 MET B CE    1 
ATOM   7802  N N     . ASP B 1 476 ? -11.816 4.888   -28.456  1.00 40.91  ? 476 ASP B N     1 
ATOM   7803  C CA    . ASP B 1 476 ? -12.550 3.698   -28.043  1.00 44.71  ? 476 ASP B CA    1 
ATOM   7804  C C     . ASP B 1 476 ? -13.941 4.129   -27.604  1.00 43.50  ? 476 ASP B C     1 
ATOM   7805  O O     . ASP B 1 476 ? -14.911 3.402   -27.764  1.00 43.30  ? 476 ASP B O     1 
ATOM   7806  C CB    . ASP B 1 476 ? -11.999 2.959   -26.812  1.00 46.28  ? 476 ASP B CB    1 
ATOM   7807  C CG    . ASP B 1 476 ? -10.858 1.967   -26.986  1.00 51.96  ? 476 ASP B CG    1 
ATOM   7808  O OD1   . ASP B 1 476 ? -10.184 1.964   -28.012  1.00 51.06  ? 476 ASP B OD1   1 
ATOM   7809  O OD2   . ASP B 1 476 ? -10.638 1.205   -26.041  1.00 68.90  ? 476 ASP B OD2   1 
ATOM   7810  N N     . ARG B 1 477 ? -14.016 5.287   -26.958  1.00 42.30  ? 477 ARG B N     1 
ATOM   7811  C CA    . ARG B 1 477 ? -15.284 5.714   -26.411  1.00 45.39  ? 477 ARG B CA    1 
ATOM   7812  C C     . ARG B 1 477 ? -16.228 5.964   -27.585  1.00 40.35  ? 477 ARG B C     1 
ATOM   7813  O O     . ARG B 1 477 ? -17.333 5.464   -27.585  1.00 39.05  ? 477 ARG B O     1 
ATOM   7814  C CB    . ARG B 1 477 ? -15.090 6.907   -25.468  1.00 46.05  ? 477 ARG B CB    1 
ATOM   7815  C CG    . ARG B 1 477 ? -16.390 7.503   -24.950  1.00 57.72  ? 477 ARG B CG    1 
ATOM   7816  C CD    . ARG B 1 477 ? -17.304 6.555   -24.174  1.00 62.42  ? 477 ARG B CD    1 
ATOM   7817  N NE    . ARG B 1 477 ? -18.670 7.079   -24.106  1.00 56.21  ? 477 ARG B NE    1 
ATOM   7818  C CZ    . ARG B 1 477 ? -19.659 6.739   -24.937  1.00 62.77  ? 477 ARG B CZ    1 
ATOM   7819  N NH1   . ARG B 1 477 ? -19.481 5.817   -25.869  1.00 64.80  ? 477 ARG B NH1   1 
ATOM   7820  N NH2   . ARG B 1 477 ? -20.846 7.309   -24.831  1.00 62.37  ? 477 ARG B NH2   1 
ATOM   7821  N N     . ILE B 1 478 ? -15.769 6.671   -28.621  1.00 41.85  ? 478 ILE B N     1 
ATOM   7822  C CA    . ILE B 1 478 ? -16.608 6.930   -29.777  1.00 38.79  ? 478 ILE B CA    1 
ATOM   7823  C C     . ILE B 1 478 ? -16.971 5.644   -30.515  1.00 35.64  ? 478 ILE B C     1 
ATOM   7824  O O     . ILE B 1 478 ? -18.134 5.477   -30.867  1.00 35.67  ? 478 ILE B O     1 
ATOM   7825  C CB    . ILE B 1 478 ? -15.968 7.982   -30.680  1.00 42.56  ? 478 ILE B CB    1 
ATOM   7826  C CG1   . ILE B 1 478 ? -15.773 9.290   -29.902  1.00 48.42  ? 478 ILE B CG1   1 
ATOM   7827  C CG2   . ILE B 1 478 ? -16.804 8.167   -31.934  1.00 42.80  ? 478 ILE B CG2   1 
ATOM   7828  C CD1   . ILE B 1 478 ? -17.042 9.828   -29.227  1.00 46.86  ? 478 ILE B CD1   1 
ATOM   7829  N N     . ALA B 1 479 ? -16.033 4.711   -30.684  1.00 34.69  ? 479 ALA B N     1 
ATOM   7830  C CA    . ALA B 1 479 ? -16.342 3.426   -31.319  1.00 38.56  ? 479 ALA B CA    1 
ATOM   7831  C C     . ALA B 1 479 ? -17.526 2.756   -30.644  1.00 40.10  ? 479 ALA B C     1 
ATOM   7832  O O     . ALA B 1 479 ? -18.360 2.160   -31.320  1.00 46.41  ? 479 ALA B O     1 
ATOM   7833  C CB    . ALA B 1 479 ? -15.179 2.465   -31.283  1.00 39.68  ? 479 ALA B CB    1 
ATOM   7834  N N     . LYS B 1 480 ? -17.587 2.851   -29.316  1.00 41.47  ? 480 LYS B N     1 
ATOM   7835  C CA    . LYS B 1 480 ? -18.582 2.122   -28.550  1.00 48.00  ? 480 LYS B CA    1 
ATOM   7836  C C     . LYS B 1 480 ? -19.971 2.721   -28.755  1.00 41.86  ? 480 LYS B C     1 
ATOM   7837  O O     . LYS B 1 480 ? -20.933 2.115   -28.333  1.00 40.69  ? 480 LYS B O     1 
ATOM   7838  C CB    . LYS B 1 480 ? -18.287 2.095   -27.045  1.00 60.97  ? 480 LYS B CB    1 
ATOM   7839  C CG    . LYS B 1 480 ? -17.047 1.345   -26.559  1.00 66.09  ? 480 LYS B CG    1 
ATOM   7840  C CD    . LYS B 1 480 ? -16.803 1.630   -25.051  1.00 84.47  ? 480 LYS B CD    1 
ATOM   7841  C CE    . LYS B 1 480 ? -15.354 1.632   -24.598  1.00 95.74  ? 480 LYS B CE    1 
ATOM   7842  N NZ    . LYS B 1 480 ? -14.721 0.301   -24.779  1.00 100.11 ? 480 LYS B NZ    1 
ATOM   7843  N N     . THR B 1 481 ? -20.116 3.840   -29.470  1.00 44.45  ? 481 THR B N     1 
ATOM   7844  C CA    . THR B 1 481 ? -21.459 4.319   -29.762  1.00 46.58  ? 481 THR B CA    1 
ATOM   7845  C C     . THR B 1 481 ? -22.028 3.627   -30.995  1.00 42.04  ? 481 THR B C     1 
ATOM   7846  O O     . THR B 1 481 ? -23.236 3.634   -31.176  1.00 38.57  ? 481 THR B O     1 
ATOM   7847  C CB    . THR B 1 481 ? -21.538 5.852   -29.819  1.00 56.70  ? 481 THR B CB    1 
ATOM   7848  O OG1   . THR B 1 481 ? -20.439 6.365   -30.550  1.00 50.21  ? 481 THR B OG1   1 
ATOM   7849  C CG2   . THR B 1 481 ? -21.507 6.481   -28.438  1.00 69.61  ? 481 THR B CG2   1 
ATOM   7850  N N     . TYR B 1 482 ? -21.181 2.973   -31.797  1.00 45.77  ? 482 TYR B N     1 
ATOM   7851  C CA    . TYR B 1 482 ? -21.627 2.330   -33.029  1.00 41.59  ? 482 TYR B CA    1 
ATOM   7852  C C     . TYR B 1 482 ? -21.856 0.838   -32.769  1.00 41.73  ? 482 TYR B C     1 
ATOM   7853  O O     . TYR B 1 482 ? -21.329 -0.013  -33.483  1.00 37.94  ? 482 TYR B O     1 
ATOM   7854  C CB    . TYR B 1 482 ? -20.648 2.698   -34.143  1.00 40.25  ? 482 TYR B CB    1 
ATOM   7855  C CG    . TYR B 1 482 ? -20.735 4.164   -34.495  1.00 45.90  ? 482 TYR B CG    1 
ATOM   7856  C CD1   . TYR B 1 482 ? -21.764 4.648   -35.276  1.00 45.51  ? 482 TYR B CD1   1 
ATOM   7857  C CD2   . TYR B 1 482 ? -19.853 5.094   -33.957  1.00 52.28  ? 482 TYR B CD2   1 
ATOM   7858  C CE1   . TYR B 1 482 ? -21.896 6.000   -35.537  1.00 47.47  ? 482 TYR B CE1   1 
ATOM   7859  C CE2   . TYR B 1 482 ? -19.941 6.447   -34.249  1.00 46.37  ? 482 TYR B CE2   1 
ATOM   7860  C CZ    . TYR B 1 482 ? -20.971 6.901   -35.043  1.00 47.08  ? 482 TYR B CZ    1 
ATOM   7861  O OH    . TYR B 1 482 ? -21.097 8.233   -35.327  1.00 46.82  ? 482 TYR B OH    1 
ATOM   7862  N N     . SER B 1 483 ? -22.749 0.555   -31.800  1.00 40.04  ? 483 SER B N     1 
ATOM   7863  C CA    . SER B 1 483 ? -22.782 -0.706  -31.081  1.00 39.90  ? 483 SER B CA    1 
ATOM   7864  C C     . SER B 1 483 ? -23.902 -1.632  -31.566  1.00 38.86  ? 483 SER B C     1 
ATOM   7865  O O     . SER B 1 483 ? -24.160 -2.664  -30.944  1.00 42.96  ? 483 SER B O     1 
ATOM   7866  C CB    . SER B 1 483 ? -22.927 -0.419  -29.586  1.00 41.12  ? 483 SER B CB    1 
ATOM   7867  O OG    . SER B 1 483 ? -24.221 0.090   -29.285  1.00 41.48  ? 483 SER B OG    1 
ATOM   7868  N N     . TRP B 1 484 ? -24.612 -1.262  -32.639  1.00 40.16  ? 484 TRP B N     1 
ATOM   7869  C CA    . TRP B 1 484 ? -25.717 -2.087  -33.128  1.00 40.57  ? 484 TRP B CA    1 
ATOM   7870  C C     . TRP B 1 484 ? -25.305 -3.557  -33.347  1.00 43.64  ? 484 TRP B C     1 
ATOM   7871  O O     . TRP B 1 484 ? -24.228 -3.866  -33.891  1.00 39.63  ? 484 TRP B O     1 
ATOM   7872  C CB    . TRP B 1 484 ? -26.273 -1.482  -34.409  1.00 39.00  ? 484 TRP B CB    1 
ATOM   7873  C CG    . TRP B 1 484 ? -27.562 -2.104  -34.824  1.00 40.90  ? 484 TRP B CG    1 
ATOM   7874  C CD1   . TRP B 1 484 ? -28.791 -1.855  -34.295  1.00 41.93  ? 484 TRP B CD1   1 
ATOM   7875  C CD2   . TRP B 1 484 ? -27.747 -3.117  -35.821  1.00 40.66  ? 484 TRP B CD2   1 
ATOM   7876  N NE1   . TRP B 1 484 ? -29.736 -2.611  -34.925  1.00 39.24  ? 484 TRP B NE1   1 
ATOM   7877  C CE2   . TRP B 1 484 ? -29.127 -3.404  -35.862  1.00 40.35  ? 484 TRP B CE2   1 
ATOM   7878  C CE3   . TRP B 1 484 ? -26.886 -3.830  -36.661  1.00 41.04  ? 484 TRP B CE3   1 
ATOM   7879  C CZ2   . TRP B 1 484 ? -29.668 -4.360  -36.728  1.00 37.87  ? 484 TRP B CZ2   1 
ATOM   7880  C CZ3   . TRP B 1 484 ? -27.422 -4.777  -37.513  1.00 40.35  ? 484 TRP B CZ3   1 
ATOM   7881  C CH2   . TRP B 1 484 ? -28.793 -5.059  -37.527  1.00 36.69  ? 484 TRP B CH2   1 
ATOM   7882  N N     . ASN B 1 485 ? -26.176 -4.462  -32.879  1.00 36.73  ? 485 ASN B N     1 
ATOM   7883  C CA    . ASN B 1 485 ? -26.005 -5.909  -32.990  1.00 40.24  ? 485 ASN B CA    1 
ATOM   7884  C C     . ASN B 1 485 ? -24.691 -6.331  -32.344  1.00 39.95  ? 485 ASN B C     1 
ATOM   7885  O O     . ASN B 1 485 ? -23.825 -6.901  -32.990  1.00 47.79  ? 485 ASN B O     1 
ATOM   7886  C CB    . ASN B 1 485 ? -26.136 -6.392  -34.437  1.00 41.83  ? 485 ASN B CB    1 
ATOM   7887  C CG    . ASN B 1 485 ? -26.088 -7.901  -34.604  1.00 42.07  ? 485 ASN B CG    1 
ATOM   7888  O OD1   . ASN B 1 485 ? -26.411 -8.650  -33.692  1.00 41.76  ? 485 ASN B OD1   1 
ATOM   7889  N ND2   . ASN B 1 485 ? -25.656 -8.359  -35.770  1.00 44.44  ? 485 ASN B ND2   1 
ATOM   7890  N N     . ASP B 1 486 ? -24.571 -6.037  -31.052  1.00 40.19  ? 486 ASP B N     1 
ATOM   7891  C CA    . ASP B 1 486 ? -23.379 -6.300  -30.271  1.00 40.50  ? 486 ASP B CA    1 
ATOM   7892  C C     . ASP B 1 486 ? -22.069 -5.938  -30.988  1.00 35.59  ? 486 ASP B C     1 
ATOM   7893  O O     . ASP B 1 486 ? -21.154 -6.734  -31.028  1.00 41.47  ? 486 ASP B O     1 
ATOM   7894  C CB    . ASP B 1 486 ? -23.431 -7.747  -29.788  1.00 44.91  ? 486 ASP B CB    1 
ATOM   7895  C CG    . ASP B 1 486 ? -22.324 -8.089  -28.805  1.00 50.58  ? 486 ASP B CG    1 
ATOM   7896  O OD1   . ASP B 1 486 ? -21.961 -7.210  -27.951  1.00 55.88  ? 486 ASP B OD1   1 
ATOM   7897  O OD2   . ASP B 1 486 ? -21.823 -9.206  -28.907  1.00 46.57  ? 486 ASP B OD2   1 
ATOM   7898  N N     . ASN B 1 487 ? -21.917 -4.704  -31.463  1.00 40.77  ? 487 ASN B N     1 
ATOM   7899  C CA    . ASN B 1 487 ? -20.659 -4.215  -32.029  1.00 42.50  ? 487 ASN B CA    1 
ATOM   7900  C C     . ASN B 1 487 ? -20.279 -5.025  -33.263  1.00 41.80  ? 487 ASN B C     1 
ATOM   7901  O O     . ASN B 1 487 ? -19.110 -5.306  -33.490  1.00 46.05  ? 487 ASN B O     1 
ATOM   7902  C CB    . ASN B 1 487 ? -19.518 -4.168  -31.006  1.00 36.67  ? 487 ASN B CB    1 
ATOM   7903  C CG    . ASN B 1 487 ? -19.941 -3.489  -29.713  1.00 39.79  ? 487 ASN B CG    1 
ATOM   7904  O OD1   . ASN B 1 487 ? -20.274 -4.171  -28.764  1.00 50.86  ? 487 ASN B OD1   1 
ATOM   7905  N ND2   . ASN B 1 487 ? -20.031 -2.173  -29.665  1.00 39.97  ? 487 ASN B ND2   1 
ATOM   7906  N N     . ALA B 1 488 ? -21.282 -5.312  -34.088  1.00 37.78  ? 488 ALA B N     1 
ATOM   7907  C CA    . ALA B 1 488 ? -21.130 -6.068  -35.320  1.00 34.34  ? 488 ALA B CA    1 
ATOM   7908  C C     . ALA B 1 488 ? -20.184 -5.401  -36.313  1.00 37.31  ? 488 ALA B C     1 
ATOM   7909  O O     . ALA B 1 488 ? -19.397 -6.098  -36.961  1.00 39.03  ? 488 ALA B O     1 
ATOM   7910  C CB    . ALA B 1 488 ? -22.482 -6.253  -35.945  1.00 33.49  ? 488 ALA B CB    1 
ATOM   7911  N N     . LEU B 1 489 ? -20.264 -4.067  -36.459  1.00 40.49  ? 489 LEU B N     1 
ATOM   7912  C CA    . LEU B 1 489 ? -19.404 -3.384  -37.420  1.00 37.50  ? 489 LEU B CA    1 
ATOM   7913  C C     . LEU B 1 489 ? -17.938 -3.531  -37.014  1.00 38.23  ? 489 LEU B C     1 
ATOM   7914  O O     . LEU B 1 489 ? -17.110 -3.884  -37.838  1.00 42.09  ? 489 LEU B O     1 
ATOM   7915  C CB    . LEU B 1 489 ? -19.825 -1.922  -37.557  1.00 34.67  ? 489 LEU B CB    1 
ATOM   7916  C CG    . LEU B 1 489 ? -19.046 -1.070  -38.551  1.00 39.38  ? 489 LEU B CG    1 
ATOM   7917  C CD1   . LEU B 1 489 ? -19.033 -1.710  -39.943  1.00 49.45  ? 489 LEU B CD1   1 
ATOM   7918  C CD2   . LEU B 1 489 ? -19.638 0.328   -38.662  1.00 42.34  ? 489 LEU B CD2   1 
ATOM   7919  N N     . TRP B 1 490 ? -17.619 -3.278  -35.742  1.00 43.00  ? 490 TRP B N     1 
ATOM   7920  C CA    . TRP B 1 490 ? -16.240 -3.229  -35.291  1.00 39.00  ? 490 TRP B CA    1 
ATOM   7921  C C     . TRP B 1 490 ? -15.646 -4.629  -35.347  1.00 36.94  ? 490 TRP B C     1 
ATOM   7922  O O     . TRP B 1 490 ? -14.484 -4.805  -35.647  1.00 36.54  ? 490 TRP B O     1 
ATOM   7923  C CB    . TRP B 1 490 ? -16.139 -2.592  -33.894  1.00 39.78  ? 490 TRP B CB    1 
ATOM   7924  C CG    . TRP B 1 490 ? -15.487 -1.255  -33.988  1.00 37.85  ? 490 TRP B CG    1 
ATOM   7925  C CD1   . TRP B 1 490 ? -14.213 -0.940  -33.609  1.00 34.70  ? 490 TRP B CD1   1 
ATOM   7926  C CD2   . TRP B 1 490 ? -16.016 -0.094  -34.649  1.00 36.69  ? 490 TRP B CD2   1 
ATOM   7927  N NE1   . TRP B 1 490 ? -13.933 0.353   -33.962  1.00 38.58  ? 490 TRP B NE1   1 
ATOM   7928  C CE2   . TRP B 1 490 ? -15.000 0.884   -34.638  1.00 35.51  ? 490 TRP B CE2   1 
ATOM   7929  C CE3   . TRP B 1 490 ? -17.226 0.204   -35.274  1.00 35.60  ? 490 TRP B CE3   1 
ATOM   7930  C CZ2   . TRP B 1 490 ? -15.172 2.143   -35.209  1.00 37.92  ? 490 TRP B CZ2   1 
ATOM   7931  C CZ3   . TRP B 1 490 ? -17.388 1.446   -35.852  1.00 35.82  ? 490 TRP B CZ3   1 
ATOM   7932  C CH2   . TRP B 1 490 ? -16.381 2.408   -35.817  1.00 35.96  ? 490 TRP B CH2   1 
ATOM   7933  N N     . LYS B 1 491 ? -16.478 -5.622  -35.107  1.00 38.59  ? 491 LYS B N     1 
ATOM   7934  C CA    . LYS B 1 491 ? -16.094 -7.004  -35.309  1.00 42.56  ? 491 LYS B CA    1 
ATOM   7935  C C     . LYS B 1 491 ? -15.658 -7.226  -36.751  1.00 42.43  ? 491 LYS B C     1 
ATOM   7936  O O     . LYS B 1 491 ? -14.661 -7.910  -36.974  1.00 44.33  ? 491 LYS B O     1 
ATOM   7937  C CB    . LYS B 1 491 ? -17.239 -7.947  -34.914  1.00 39.48  ? 491 LYS B CB    1 
ATOM   7938  C CG    . LYS B 1 491 ? -17.276 -8.189  -33.419  1.00 43.04  ? 491 LYS B CG    1 
ATOM   7939  C CD    . LYS B 1 491 ? -18.370 -9.100  -32.967  1.00 47.97  ? 491 LYS B CD    1 
ATOM   7940  C CE    . LYS B 1 491 ? -18.667 -8.912  -31.496  1.00 45.59  ? 491 LYS B CE    1 
ATOM   7941  N NZ    . LYS B 1 491 ? -19.999 -9.461  -31.178  1.00 46.47  ? 491 LYS B NZ    1 
ATOM   7942  N N     . MET B 1 492 ? -16.391 -6.654  -37.710  1.00 41.59  ? 492 MET B N     1 
ATOM   7943  C CA    . MET B 1 492 ? -15.960 -6.731  -39.098  1.00 44.02  ? 492 MET B CA    1 
ATOM   7944  C C     . MET B 1 492 ? -14.604 -6.042  -39.307  1.00 43.87  ? 492 MET B C     1 
ATOM   7945  O O     . MET B 1 492 ? -13.719 -6.618  -39.947  1.00 51.41  ? 492 MET B O     1 
ATOM   7946  C CB    . MET B 1 492 ? -16.978 -6.122  -40.066  1.00 47.26  ? 492 MET B CB    1 
ATOM   7947  C CG    . MET B 1 492 ? -16.598 -6.383  -41.515  1.00 50.92  ? 492 MET B CG    1 
ATOM   7948  S SD    . MET B 1 492 ? -17.647 -5.563  -42.658  1.00 55.50  ? 492 MET B SD    1 
ATOM   7949  C CE    . MET B 1 492 ? -16.982 -3.908  -42.589  1.00 51.55  ? 492 MET B CE    1 
ATOM   7950  N N     . HIS B 1 493 ? -14.434 -4.808  -38.807  1.00 44.02  ? 493 HIS B N     1 
ATOM   7951  C CA    . HIS B 1 493 ? -13.162 -4.094  -38.890  1.00 42.57  ? 493 HIS B CA    1 
ATOM   7952  C C     . HIS B 1 493 ? -12.012 -4.913  -38.288  1.00 45.50  ? 493 HIS B C     1 
ATOM   7953  O O     . HIS B 1 493 ? -10.934 -4.972  -38.858  1.00 41.81  ? 493 HIS B O     1 
ATOM   7954  C CB    . HIS B 1 493 ? -13.239 -2.721  -38.218  1.00 44.23  ? 493 HIS B CB    1 
ATOM   7955  C CG    . HIS B 1 493 ? -14.227 -1.747  -38.784  1.00 46.73  ? 493 HIS B CG    1 
ATOM   7956  N ND1   . HIS B 1 493 ? -14.440 -1.524  -40.129  1.00 45.82  ? 493 HIS B ND1   1 
ATOM   7957  C CD2   . HIS B 1 493 ? -15.023 -0.879  -38.124  1.00 41.80  ? 493 HIS B CD2   1 
ATOM   7958  C CE1   . HIS B 1 493 ? -15.352 -0.561  -40.255  1.00 48.11  ? 493 HIS B CE1   1 
ATOM   7959  N NE2   . HIS B 1 493 ? -15.718 -0.155  -39.044  1.00 40.17  ? 493 HIS B NE2   1 
ATOM   7960  N N     . GLU B 1 494 ? -12.244 -5.577  -37.146  1.00 51.95  ? 494 GLU B N     1 
ATOM   7961  C CA    . GLU B 1 494 ? -11.238 -6.437  -36.539  1.00 54.02  ? 494 GLU B CA    1 
ATOM   7962  C C     . GLU B 1 494 ? -10.922 -7.604  -37.488  1.00 51.13  ? 494 GLU B C     1 
ATOM   7963  O O     . GLU B 1 494 ? -9.775  -8.042  -37.587  1.00 52.35  ? 494 GLU B O     1 
ATOM   7964  C CB    . GLU B 1 494 ? -11.650 -6.939  -35.138  1.00 58.11  ? 494 GLU B CB    1 
ATOM   7965  C CG    . GLU B 1 494 ? -12.079 -5.868  -34.117  1.00 63.12  ? 494 GLU B CG    1 
ATOM   7966  C CD    . GLU B 1 494 ? -11.038 -5.115  -33.283  1.00 85.60  ? 494 GLU B CD    1 
ATOM   7967  O OE1   . GLU B 1 494 ? -9.770  -5.280  -33.497  1.00 66.65  ? 494 GLU B OE1   1 
ATOM   7968  O OE2   . GLU B 1 494 ? -11.503 -4.343  -32.379  1.00 85.40  ? 494 GLU B OE2   1 
ATOM   7969  N N     . THR B 1 495 ? -11.925 -8.136  -38.200  1.00 51.04  ? 495 THR B N     1 
ATOM   7970  C CA    . THR B 1 495 ? -11.667 -9.216  -39.140  1.00 44.28  ? 495 THR B CA    1 
ATOM   7971  C C     . THR B 1 495 ? -10.720 -8.757  -40.251  1.00 45.60  ? 495 THR B C     1 
ATOM   7972  O O     . THR B 1 495 ? -9.849  -9.523  -40.638  1.00 47.18  ? 495 THR B O     1 
ATOM   7973  C CB    . THR B 1 495 ? -12.949 -9.752  -39.779  1.00 45.60  ? 495 THR B CB    1 
ATOM   7974  O OG1   . THR B 1 495 ? -13.770 -10.327 -38.767  1.00 46.99  ? 495 THR B OG1   1 
ATOM   7975  C CG2   . THR B 1 495 ? -12.681 -10.811 -40.828  1.00 45.68  ? 495 THR B CG2   1 
ATOM   7976  N N     . ILE B 1 496 ? -10.899 -7.528  -40.766  1.00 44.91  ? 496 ILE B N     1 
ATOM   7977  C CA    . ILE B 1 496 ? -10.121 -7.018  -41.892  1.00 43.63  ? 496 ILE B CA    1 
ATOM   7978  C C     . ILE B 1 496 ? -8.707  -6.701  -41.417  1.00 43.35  ? 496 ILE B C     1 
ATOM   7979  O O     . ILE B 1 496 ? -7.724  -7.003  -42.105  1.00 49.71  ? 496 ILE B O     1 
ATOM   7980  C CB    . ILE B 1 496 ? -10.826 -5.789  -42.508  1.00 45.57  ? 496 ILE B CB    1 
ATOM   7981  C CG1   . ILE B 1 496 ? -11.982 -6.203  -43.410  1.00 47.01  ? 496 ILE B CG1   1 
ATOM   7982  C CG2   . ILE B 1 496 ? -9.875  -4.873  -43.262  1.00 47.66  ? 496 ILE B CG2   1 
ATOM   7983  C CD1   . ILE B 1 496 ? -12.939 -5.074  -43.665  1.00 54.72  ? 496 ILE B CD1   1 
ATOM   7984  N N     . LYS B 1 497 ? -8.642  -6.076  -40.238  1.00 38.87  ? 497 LYS B N     1 
ATOM   7985  C CA    . LYS B 1 497 ? -7.407  -5.725  -39.568  1.00 42.99  ? 497 LYS B CA    1 
ATOM   7986  C C     . LYS B 1 497 ? -6.483  -6.936  -39.389  1.00 44.52  ? 497 LYS B C     1 
ATOM   7987  O O     . LYS B 1 497 ? -5.280  -6.802  -39.513  1.00 53.16  ? 497 LYS B O     1 
ATOM   7988  C CB    . LYS B 1 497 ? -7.758  -5.119  -38.209  1.00 43.99  ? 497 LYS B CB    1 
ATOM   7989  C CG    . LYS B 1 497 ? -6.568  -4.715  -37.345  1.00 49.72  ? 497 LYS B CG    1 
ATOM   7990  C CD    . LYS B 1 497 ? -5.652  -3.623  -37.888  1.00 47.48  ? 497 LYS B CD    1 
ATOM   7991  C CE    . LYS B 1 497 ? -4.543  -3.302  -36.901  1.00 42.82  ? 497 LYS B CE    1 
ATOM   7992  N NZ    . LYS B 1 497 ? -3.491  -2.427  -37.472  1.00 42.49  ? 497 LYS B NZ    1 
ATOM   7993  N N     . ASP B 1 498 ? -7.035  -8.103  -39.065  1.00 45.81  ? 498 ASP B N     1 
ATOM   7994  C CA    . ASP B 1 498 ? -6.255  -9.286  -38.747  1.00 48.42  ? 498 ASP B CA    1 
ATOM   7995  C C     . ASP B 1 498 ? -5.794  -9.981  -40.025  1.00 53.91  ? 498 ASP B C     1 
ATOM   7996  O O     . ASP B 1 498 ? -4.760  -10.665 -40.035  1.00 53.87  ? 498 ASP B O     1 
ATOM   7997  C CB    . ASP B 1 498 ? -7.064  -10.244 -37.871  1.00 46.16  ? 498 ASP B CB    1 
ATOM   7998  C CG    . ASP B 1 498 ? -7.288  -9.757  -36.447  1.00 54.54  ? 498 ASP B CG    1 
ATOM   7999  O OD1   . ASP B 1 498 ? -6.574  -8.798  -35.983  1.00 53.00  ? 498 ASP B OD1   1 
ATOM   8000  O OD2   . ASP B 1 498 ? -8.197  -10.324 -35.804  1.00 62.76  ? 498 ASP B OD2   1 
ATOM   8001  N N     . ALA B 1 499 ? -6.598  -9.824  -41.085  1.00 52.51  ? 499 ALA B N     1 
ATOM   8002  C CA    . ALA B 1 499 ? -6.230  -10.272 -42.413  1.00 49.38  ? 499 ALA B CA    1 
ATOM   8003  C C     . ALA B 1 499 ? -5.071  -9.435  -42.959  1.00 46.70  ? 499 ALA B C     1 
ATOM   8004  O O     . ALA B 1 499 ? -4.101  -10.012 -43.403  1.00 55.65  ? 499 ALA B O     1 
ATOM   8005  C CB    . ALA B 1 499 ? -7.435  -10.202 -43.313  1.00 52.07  ? 499 ALA B CB    1 
ATOM   8006  N N     . LEU B 1 500 ? -5.170  -8.096  -42.923  1.00 43.82  ? 500 LEU B N     1 
ATOM   8007  C CA    . LEU B 1 500 ? -4.169  -7.229  -43.539  1.00 42.58  ? 500 LEU B CA    1 
ATOM   8008  C C     . LEU B 1 500 ? -2.932  -7.059  -42.656  1.00 50.41  ? 500 LEU B C     1 
ATOM   8009  O O     . LEU B 1 500 ? -1.819  -7.053  -43.178  1.00 49.20  ? 500 LEU B O     1 
ATOM   8010  C CB    . LEU B 1 500 ? -4.750  -5.841  -43.816  1.00 38.65  ? 500 LEU B CB    1 
ATOM   8011  C CG    . LEU B 1 500 ? -5.840  -5.778  -44.878  1.00 37.87  ? 500 LEU B CG    1 
ATOM   8012  C CD1   . LEU B 1 500 ? -6.395  -4.373  -44.976  1.00 37.45  ? 500 LEU B CD1   1 
ATOM   8013  C CD2   . LEU B 1 500 ? -5.290  -6.224  -46.218  1.00 41.53  ? 500 LEU B CD2   1 
ATOM   8014  N N     . ASP B 1 501 ? -3.144  -6.841  -41.345  1.00 52.23  ? 501 ASP B N     1 
ATOM   8015  C CA    . ASP B 1 501 ? -2.082  -6.612  -40.380  1.00 43.98  ? 501 ASP B CA    1 
ATOM   8016  C C     . ASP B 1 501 ? -2.086  -7.704  -39.316  1.00 43.10  ? 501 ASP B C     1 
ATOM   8017  O O     . ASP B 1 501 ? -2.360  -7.438  -38.157  1.00 42.39  ? 501 ASP B O     1 
ATOM   8018  C CB    . ASP B 1 501 ? -2.265  -5.269  -39.678  1.00 45.96  ? 501 ASP B CB    1 
ATOM   8019  C CG    . ASP B 1 501 ? -1.082  -4.875  -38.807  1.00 51.57  ? 501 ASP B CG    1 
ATOM   8020  O OD1   . ASP B 1 501 ? -0.074  -5.656  -38.771  1.00 57.40  ? 501 ASP B OD1   1 
ATOM   8021  O OD2   . ASP B 1 501 ? -1.162  -3.779  -38.185  1.00 53.28  ? 501 ASP B OD2   1 
ATOM   8022  N N     . PRO B 1 502 ? -1.769  -8.971  -39.641  1.00 49.91  ? 502 PRO B N     1 
ATOM   8023  C CA    . PRO B 1 502 ? -1.761  -10.023 -38.622  1.00 45.41  ? 502 PRO B CA    1 
ATOM   8024  C C     . PRO B 1 502 ? -0.857  -9.743  -37.416  1.00 51.65  ? 502 PRO B C     1 
ATOM   8025  O O     . PRO B 1 502 ? -1.176  -10.182 -36.319  1.00 58.66  ? 502 PRO B O     1 
ATOM   8026  C CB    . PRO B 1 502 ? -1.318  -11.280 -39.394  1.00 43.40  ? 502 PRO B CB    1 
ATOM   8027  C CG    . PRO B 1 502 ? -0.710  -10.759 -40.692  1.00 42.93  ? 502 PRO B CG    1 
ATOM   8028  C CD    . PRO B 1 502 ? -1.446  -9.475  -40.988  1.00 46.92  ? 502 PRO B CD    1 
ATOM   8029  N N     . ASN B 1 503 ? 0.254   -9.010  -37.578  1.00 52.80  ? 503 ASN B N     1 
ATOM   8030  C CA    . ASN B 1 503 ? 1.157   -8.792  -36.455  1.00 49.51  ? 503 ASN B CA    1 
ATOM   8031  C C     . ASN B 1 503 ? 0.795   -7.558  -35.650  1.00 56.75  ? 503 ASN B C     1 
ATOM   8032  O O     . ASN B 1 503 ? 1.484   -7.279  -34.674  1.00 65.25  ? 503 ASN B O     1 
ATOM   8033  C CB    . ASN B 1 503 ? 2.615   -8.609  -36.872  1.00 54.76  ? 503 ASN B CB    1 
ATOM   8034  C CG    . ASN B 1 503 ? 3.141   -9.860  -37.535  1.00 55.89  ? 503 ASN B CG    1 
ATOM   8035  O OD1   . ASN B 1 503 ? 2.890   -10.963 -37.046  1.00 53.55  ? 503 ASN B OD1   1 
ATOM   8036  N ND2   . ASN B 1 503 ? 3.769   -9.694  -38.691  1.00 49.14  ? 503 ASN B ND2   1 
ATOM   8037  N N     . GLY B 1 504 ? -0.252  -6.831  -36.062  1.00 57.69  ? 504 GLY B N     1 
ATOM   8038  C CA    . GLY B 1 504 ? -0.765  -5.696  -35.311  1.00 52.67  ? 504 GLY B CA    1 
ATOM   8039  C C     . GLY B 1 504 ? 0.273   -4.590  -35.080  1.00 55.03  ? 504 GLY B C     1 
ATOM   8040  O O     . GLY B 1 504 ? 0.291   -4.022  -33.982  1.00 53.45  ? 504 GLY B O     1 
ATOM   8041  N N     . ILE B 1 505 ? 1.069   -4.255  -36.125  1.00 54.44  ? 505 ILE B N     1 
ATOM   8042  C CA    . ILE B 1 505 ? 2.060   -3.182  -36.062  1.00 56.50  ? 505 ILE B CA    1 
ATOM   8043  C C     . ILE B 1 505 ? 1.583   -1.843  -36.637  1.00 49.04  ? 505 ILE B C     1 
ATOM   8044  O O     . ILE B 1 505 ? 2.391   -0.934  -36.758  1.00 56.72  ? 505 ILE B O     1 
ATOM   8045  C CB    . ILE B 1 505 ? 3.395   -3.607  -36.713  1.00 63.45  ? 505 ILE B CB    1 
ATOM   8046  C CG1   . ILE B 1 505 ? 3.250   -4.091  -38.164  1.00 64.81  ? 505 ILE B CG1   1 
ATOM   8047  C CG2   . ILE B 1 505 ? 4.061   -4.665  -35.847  1.00 64.57  ? 505 ILE B CG2   1 
ATOM   8048  C CD1   . ILE B 1 505 ? 2.733   -3.069  -39.141  1.00 59.86  ? 505 ILE B CD1   1 
ATOM   8049  N N     . LEU B 1 506 ? 0.304   -1.652  -36.963  1.00 53.12  ? 506 LEU B N     1 
ATOM   8050  C CA    . LEU B 1 506 ? -0.138  -0.340  -37.436  1.00 58.36  ? 506 LEU B CA    1 
ATOM   8051  C C     . LEU B 1 506 ? -1.141  0.329   -36.486  1.00 54.52  ? 506 LEU B C     1 
ATOM   8052  O O     . LEU B 1 506 ? -2.236  -0.178  -36.250  1.00 53.70  ? 506 LEU B O     1 
ATOM   8053  C CB    . LEU B 1 506 ? -0.739  -0.474  -38.842  1.00 65.22  ? 506 LEU B CB    1 
ATOM   8054  C CG    . LEU B 1 506 ? 0.203   -0.226  -40.023  1.00 73.23  ? 506 LEU B CG    1 
ATOM   8055  C CD1   . LEU B 1 506 ? -0.580  0.206   -41.266  1.00 70.10  ? 506 LEU B CD1   1 
ATOM   8056  C CD2   . LEU B 1 506 ? 1.258   0.818   -39.685  1.00 78.62  ? 506 LEU B CD2   1 
ATOM   8057  N N     . ALA B 1 507 ? -0.747  1.495   -35.950  1.00 52.61  ? 507 ALA B N     1 
ATOM   8058  C CA    . ALA B 1 507 ? -1.598  2.372   -35.151  1.00 45.55  ? 507 ALA B CA    1 
ATOM   8059  C C     . ALA B 1 507 ? -2.593  1.574   -34.314  1.00 42.55  ? 507 ALA B C     1 
ATOM   8060  O O     . ALA B 1 507 ? -3.797  1.693   -34.457  1.00 36.12  ? 507 ALA B O     1 
ATOM   8061  C CB    . ALA B 1 507 ? -2.304  3.364   -36.039  1.00 44.71  ? 507 ALA B CB    1 
ATOM   8062  N N     . PRO B 1 508 ? -2.123  0.723   -33.390  1.00 48.26  ? 508 PRO B N     1 
ATOM   8063  C CA    . PRO B 1 508 ? -3.041  0.038   -32.481  1.00 50.56  ? 508 PRO B CA    1 
ATOM   8064  C C     . PRO B 1 508 ? -3.986  0.986   -31.747  1.00 50.11  ? 508 PRO B C     1 
ATOM   8065  O O     . PRO B 1 508 ? -3.541  1.958   -31.121  1.00 59.73  ? 508 PRO B O     1 
ATOM   8066  C CB    . PRO B 1 508 ? -2.068  -0.661  -31.520  1.00 53.64  ? 508 PRO B CB    1 
ATOM   8067  C CG    . PRO B 1 508 ? -0.835  -0.922  -32.384  1.00 48.86  ? 508 PRO B CG    1 
ATOM   8068  C CD    . PRO B 1 508 ? -0.708  0.351   -33.185  1.00 46.10  ? 508 PRO B CD    1 
ATOM   8069  N N     . GLY B 1 509 ? -5.288  0.701   -31.872  1.00 44.89  ? 509 GLY B N     1 
ATOM   8070  C CA    . GLY B 1 509 ? -6.328  1.447   -31.175  1.00 46.22  ? 509 GLY B CA    1 
ATOM   8071  C C     . GLY B 1 509 ? -6.917  2.627   -31.953  1.00 44.83  ? 509 GLY B C     1 
ATOM   8072  O O     . GLY B 1 509 ? -7.790  3.316   -31.426  1.00 50.23  ? 509 GLY B O     1 
ATOM   8073  N N     . LYS B 1 510 ? -6.455  2.855   -33.194  1.00 47.55  ? 510 LYS B N     1 
ATOM   8074  C CA    . LYS B 1 510 ? -6.975  3.897   -34.075  1.00 43.64  ? 510 LYS B CA    1 
ATOM   8075  C C     . LYS B 1 510 ? -8.440  3.596   -34.396  1.00 40.41  ? 510 LYS B C     1 
ATOM   8076  O O     . LYS B 1 510 ? -8.765  2.495   -34.839  1.00 35.75  ? 510 LYS B O     1 
ATOM   8077  C CB    . LYS B 1 510 ? -6.117  3.944   -35.346  1.00 55.17  ? 510 LYS B CB    1 
ATOM   8078  C CG    . LYS B 1 510 ? -6.559  4.899   -36.449  1.00 57.68  ? 510 LYS B CG    1 
ATOM   8079  C CD    . LYS B 1 510 ? -6.613  6.354   -36.045  1.00 58.59  ? 510 LYS B CD    1 
ATOM   8080  C CE    . LYS B 1 510 ? -7.247  7.215   -37.120  1.00 62.05  ? 510 LYS B CE    1 
ATOM   8081  N NZ    . LYS B 1 510 ? -8.112  8.291   -36.573  1.00 58.31  ? 510 LYS B NZ    1 
ATOM   8082  N N     . SER B 1 511 ? -9.333  4.544   -34.079  1.00 37.50  ? 511 SER B N     1 
ATOM   8083  C CA    . SER B 1 511 ? -10.758 4.377   -34.312  1.00 36.80  ? 511 SER B CA    1 
ATOM   8084  C C     . SER B 1 511 ? -11.304 3.210   -33.511  1.00 40.56  ? 511 SER B C     1 
ATOM   8085  O O     . SER B 1 511 ? -12.389 2.743   -33.814  1.00 43.12  ? 511 SER B O     1 
ATOM   8086  C CB    . SER B 1 511 ? -11.080 4.208   -35.784  1.00 36.09  ? 511 SER B CB    1 
ATOM   8087  O OG    . SER B 1 511 ? -10.598 5.321   -36.552  1.00 36.50  ? 511 SER B OG    1 
ATOM   8088  N N     . GLY B 1 512 ? -10.557 2.770   -32.487  1.00 42.76  ? 512 GLY B N     1 
ATOM   8089  C CA    . GLY B 1 512 ? -10.957 1.645   -31.661  1.00 40.85  ? 512 GLY B CA    1 
ATOM   8090  C C     . GLY B 1 512 ? -10.725 0.260   -32.265  1.00 41.56  ? 512 GLY B C     1 
ATOM   8091  O O     . GLY B 1 512 ? -11.367 -0.698  -31.818  1.00 51.16  ? 512 GLY B O     1 
ATOM   8092  N N     . ILE B 1 513 ? -9.755  0.123   -33.183  1.00 41.43  ? 513 ILE B N     1 
ATOM   8093  C CA    . ILE B 1 513 ? -9.450  -1.144  -33.834  1.00 41.05  ? 513 ILE B CA    1 
ATOM   8094  C C     . ILE B 1 513 ? -8.104  -1.700  -33.351  1.00 46.30  ? 513 ILE B C     1 
ATOM   8095  O O     . ILE B 1 513 ? -7.071  -1.103  -33.668  1.00 49.01  ? 513 ILE B O     1 
ATOM   8096  C CB    . ILE B 1 513 ? -9.442  -0.891  -35.350  1.00 42.57  ? 513 ILE B CB    1 
ATOM   8097  C CG1   . ILE B 1 513 ? -10.768 -0.289  -35.826  1.00 46.74  ? 513 ILE B CG1   1 
ATOM   8098  C CG2   . ILE B 1 513 ? -9.082  -2.161  -36.110  1.00 43.97  ? 513 ILE B CG2   1 
ATOM   8099  C CD1   . ILE B 1 513 ? -10.748 0.314   -37.259  1.00 44.28  ? 513 ILE B CD1   1 
ATOM   8100  N N     . TRP B 1 514 ? -8.059  -2.875  -32.671  1.00 49.21  ? 514 TRP B N     1 
ATOM   8101  C CA    . TRP B 1 514 ? -6.832  -3.236  -31.945  1.00 52.99  ? 514 TRP B CA    1 
ATOM   8102  C C     . TRP B 1 514 ? -5.941  -4.300  -32.640  1.00 61.41  ? 514 TRP B C     1 
ATOM   8103  O O     . TRP B 1 514 ? -4.656  -4.163  -32.774  1.00 56.88  ? 514 TRP B O     1 
ATOM   8104  C CB    . TRP B 1 514 ? -7.218  -3.558  -30.482  1.00 46.24  ? 514 TRP B CB    1 
ATOM   8105  C CG    . TRP B 1 514 ? -7.527  -2.314  -29.703  1.00 40.58  ? 514 TRP B CG    1 
ATOM   8106  C CD1   . TRP B 1 514 ? -8.746  -1.745  -29.554  1.00 38.02  ? 514 TRP B CD1   1 
ATOM   8107  C CD2   . TRP B 1 514 ? -6.601  -1.422  -29.048  1.00 37.86  ? 514 TRP B CD2   1 
ATOM   8108  N NE1   . TRP B 1 514 ? -8.653  -0.585  -28.843  1.00 41.49  ? 514 TRP B NE1   1 
ATOM   8109  C CE2   . TRP B 1 514 ? -7.347  -0.370  -28.508  1.00 40.18  ? 514 TRP B CE2   1 
ATOM   8110  C CE3   . TRP B 1 514 ? -5.221  -1.422  -28.841  1.00 38.98  ? 514 TRP B CE3   1 
ATOM   8111  C CZ2   . TRP B 1 514 ? -6.761  0.674   -27.799  1.00 43.93  ? 514 TRP B CZ2   1 
ATOM   8112  C CZ3   . TRP B 1 514 ? -4.632  -0.397  -28.140  1.00 37.52  ? 514 TRP B CZ3   1 
ATOM   8113  C CH2   . TRP B 1 514 ? -5.396  0.635   -27.618  1.00 41.89  ? 514 TRP B CH2   1 
ATOM   8114  N N     . GLY B 1 515 ? -6.661  -5.347  -33.091  1.00 54.71  ? 515 GLY B N     1 
ATOM   8115  C CA    . GLY B 1 515 ? -6.077  -6.575  -33.632  1.00 62.65  ? 515 GLY B CA    1 
ATOM   8116  C C     . GLY B 1 515 ? -6.028  -7.698  -32.589  1.00 59.11  ? 515 GLY B C     1 
ATOM   8117  O O     . GLY B 1 515 ? -5.937  -7.390  -31.402  1.00 59.91  ? 515 GLY B O     1 
ATOM   8118  N N     . LYS B 1 516 ? -6.012  -8.976  -33.032  1.00 62.30  ? 516 LYS B N     1 
ATOM   8119  C CA    . LYS B 1 516 ? -6.042  -10.147 -32.145  1.00 63.13  ? 516 LYS B CA    1 
ATOM   8120  C C     . LYS B 1 516 ? -4.944  -10.143 -31.072  1.00 58.34  ? 516 LYS B C     1 
ATOM   8121  O O     . LYS B 1 516 ? -5.167  -10.644 -29.972  1.00 53.99  ? 516 LYS B O     1 
ATOM   8122  C CB    . LYS B 1 516 ? -6.010  -11.502 -32.873  1.00 65.15  ? 516 LYS B CB    1 
ATOM   8123  C CG    . LYS B 1 516 ? -4.876  -11.779 -33.861  1.00 77.73  ? 516 LYS B CG    1 
ATOM   8124  C CD    . LYS B 1 516 ? -4.777  -13.271 -34.286  1.00 88.58  ? 516 LYS B CD    1 
ATOM   8125  C CE    . LYS B 1 516 ? -4.846  -13.543 -35.785  1.00 91.69  ? 516 LYS B CE    1 
ATOM   8126  N NZ    . LYS B 1 516 ? -3.636  -13.120 -36.532  1.00 89.00  ? 516 LYS B NZ    1 
ATOM   8127  N N     . ASN B 1 517 ? -3.768  -9.574  -31.338  1.00 55.47  ? 517 ASN B N     1 
ATOM   8128  C CA    . ASN B 1 517 ? -2.706  -9.633  -30.339  1.00 61.30  ? 517 ASN B CA    1 
ATOM   8129  C C     . ASN B 1 517 ? -3.021  -8.830  -29.079  1.00 61.79  ? 517 ASN B C     1 
ATOM   8130  O O     . ASN B 1 517 ? -2.350  -9.074  -28.091  1.00 67.82  ? 517 ASN B O     1 
ATOM   8131  C CB    . ASN B 1 517 ? -1.362  -9.128  -30.867  1.00 61.93  ? 517 ASN B CB    1 
ATOM   8132  C CG    . ASN B 1 517 ? -0.772  -10.088 -31.868  1.00 64.88  ? 517 ASN B CG    1 
ATOM   8133  O OD1   . ASN B 1 517 ? -1.026  -11.290 -31.787  1.00 65.55  ? 517 ASN B OD1   1 
ATOM   8134  N ND2   . ASN B 1 517 ? 0.004   -9.564  -32.805  1.00 61.33  ? 517 ASN B ND2   1 
ATOM   8135  N N     . ARG B 1 518 ? -3.967  -7.867  -29.123  1.00 68.28  ? 518 ARG B N     1 
ATOM   8136  C CA    . ARG B 1 518 ? -4.191  -6.935  -28.022  1.00 61.04  ? 518 ARG B CA    1 
ATOM   8137  C C     . ARG B 1 518 ? -5.668  -6.721  -27.666  1.00 59.26  ? 518 ARG B C     1 
ATOM   8138  O O     . ARG B 1 518 ? -5.952  -5.734  -27.009  1.00 60.85  ? 518 ARG B O     1 
ATOM   8139  C CB    . ARG B 1 518 ? -3.629  -5.547  -28.363  1.00 67.23  ? 518 ARG B CB    1 
ATOM   8140  C CG    . ARG B 1 518 ? -2.210  -5.555  -28.913  1.00 75.04  ? 518 ARG B CG    1 
ATOM   8141  C CD    . ARG B 1 518 ? -1.446  -4.247  -28.750  1.00 75.71  ? 518 ARG B CD    1 
ATOM   8142  N NE    . ARG B 1 518 ? -0.626  -4.017  -29.942  1.00 98.65  ? 518 ARG B NE    1 
ATOM   8143  C CZ    . ARG B 1 518 ? 0.707   -3.938  -29.993  1.00 105.81 ? 518 ARG B CZ    1 
ATOM   8144  N NH1   . ARG B 1 518 ? 1.437   -3.922  -28.885  1.00 101.36 ? 518 ARG B NH1   1 
ATOM   8145  N NH2   . ARG B 1 518 ? 1.300   -3.857  -31.176  1.00 89.99  ? 518 ARG B NH2   1 
ATOM   8146  N N     . ARG B 1 519 ? -6.624  -7.585  -28.049  1.00 62.79  ? 519 ARG B N     1 
ATOM   8147  C CA    . ARG B 1 519 ? -8.018  -7.304  -27.706  1.00 70.20  ? 519 ARG B CA    1 
ATOM   8148  C C     . ARG B 1 519 ? -8.682  -8.512  -27.039  1.00 68.61  ? 519 ARG B C     1 
ATOM   8149  O O     . ARG B 1 519 ? -7.964  -9.215  -26.328  1.00 72.15  ? 519 ARG B O     1 
ATOM   8150  C CB    . ARG B 1 519 ? -8.820  -6.893  -28.945  1.00 67.29  ? 519 ARG B CB    1 
ATOM   8151  C CG    . ARG B 1 519 ? -9.205  -8.064  -29.826  1.00 64.62  ? 519 ARG B CG    1 
ATOM   8152  C CD    . ARG B 1 519 ? -10.176 -7.752  -30.943  1.00 60.22  ? 519 ARG B CD    1 
ATOM   8153  N NE    . ARG B 1 519 ? -10.249 -8.994  -31.721  1.00 59.85  ? 519 ARG B NE    1 
ATOM   8154  C CZ    . ARG B 1 519 ? -9.575  -9.272  -32.839  1.00 62.42  ? 519 ARG B CZ    1 
ATOM   8155  N NH1   . ARG B 1 519 ? -9.060  -8.316  -33.600  1.00 69.29  ? 519 ARG B NH1   1 
ATOM   8156  N NH2   . ARG B 1 519 ? -9.475  -10.529 -33.235  1.00 56.74  ? 519 ARG B NH2   1 
ATOM   8157  N N     . ALA C 1 2   ? -29.252 -29.677 -68.585  1.00 104.08 ? 2   ALA C N     1 
ATOM   8158  C CA    . ALA C 1 2   ? -29.000 -29.574 -67.128  1.00 104.81 ? 2   ALA C CA    1 
ATOM   8159  C C     . ALA C 1 2   ? -27.878 -28.569 -66.895  1.00 116.98 ? 2   ALA C C     1 
ATOM   8160  O O     . ALA C 1 2   ? -27.182 -28.166 -67.827  1.00 110.27 ? 2   ALA C O     1 
ATOM   8161  C CB    . ALA C 1 2   ? -28.652 -30.930 -66.542  1.00 95.93  ? 2   ALA C CB    1 
ATOM   8162  N N     . ALA C 1 3   ? -27.736 -28.158 -65.634  1.00 121.29 ? 3   ALA C N     1 
ATOM   8163  C CA    . ALA C 1 3   ? -26.519 -27.520 -65.165  1.00 117.26 ? 3   ALA C CA    1 
ATOM   8164  C C     . ALA C 1 3   ? -25.809 -28.467 -64.188  1.00 109.12 ? 3   ALA C C     1 
ATOM   8165  O O     . ALA C 1 3   ? -26.449 -29.218 -63.435  1.00 81.18  ? 3   ALA C O     1 
ATOM   8166  C CB    . ALA C 1 3   ? -26.842 -26.175 -64.555  1.00 120.71 ? 3   ALA C CB    1 
ATOM   8167  N N     . PRO C 1 4   ? -24.453 -28.478 -64.200  1.00 95.96  ? 4   PRO C N     1 
ATOM   8168  C CA    . PRO C 1 4   ? -23.679 -29.418 -63.388  1.00 89.57  ? 4   PRO C CA    1 
ATOM   8169  C C     . PRO C 1 4   ? -23.551 -28.973 -61.935  1.00 84.58  ? 4   PRO C C     1 
ATOM   8170  O O     . PRO C 1 4   ? -23.701 -27.791 -61.643  1.00 86.93  ? 4   PRO C O     1 
ATOM   8171  C CB    . PRO C 1 4   ? -22.305 -29.394 -64.086  1.00 93.50  ? 4   PRO C CB    1 
ATOM   8172  C CG    . PRO C 1 4   ? -22.181 -27.975 -64.633  1.00 94.43  ? 4   PRO C CG    1 
ATOM   8173  C CD    . PRO C 1 4   ? -23.596 -27.583 -65.007  1.00 95.47  ? 4   PRO C CD    1 
ATOM   8174  N N     . LEU C 1 5   ? -23.255 -29.920 -61.035  1.00 82.70  ? 5   LEU C N     1 
ATOM   8175  C CA    . LEU C 1 5   ? -22.820 -29.580 -59.688  1.00 78.99  ? 5   LEU C CA    1 
ATOM   8176  C C     . LEU C 1 5   ? -21.598 -28.670 -59.825  1.00 79.75  ? 5   LEU C C     1 
ATOM   8177  O O     . LEU C 1 5   ? -20.958 -28.669 -60.867  1.00 73.52  ? 5   LEU C O     1 
ATOM   8178  C CB    . LEU C 1 5   ? -22.502 -30.849 -58.883  1.00 79.46  ? 5   LEU C CB    1 
ATOM   8179  C CG    . LEU C 1 5   ? -23.674 -31.784 -58.557  1.00 81.40  ? 5   LEU C CG    1 
ATOM   8180  C CD1   . LEU C 1 5   ? -23.198 -33.048 -57.849  1.00 79.83  ? 5   LEU C CD1   1 
ATOM   8181  C CD2   . LEU C 1 5   ? -24.722 -31.095 -57.699  1.00 86.40  ? 5   LEU C CD2   1 
ATOM   8182  N N     . PRO C 1 6   ? -21.288 -27.794 -58.844  1.00 82.06  ? 6   PRO C N     1 
ATOM   8183  C CA    . PRO C 1 6   ? -20.118 -26.933 -58.954  1.00 83.77  ? 6   PRO C CA    1 
ATOM   8184  C C     . PRO C 1 6   ? -18.909 -27.667 -58.378  1.00 80.97  ? 6   PRO C C     1 
ATOM   8185  O O     . PRO C 1 6   ? -19.060 -28.511 -57.498  1.00 67.18  ? 6   PRO C O     1 
ATOM   8186  C CB    . PRO C 1 6   ? -20.559 -25.694 -58.160  1.00 80.71  ? 6   PRO C CB    1 
ATOM   8187  C CG    . PRO C 1 6   ? -21.451 -26.263 -57.058  1.00 85.80  ? 6   PRO C CG    1 
ATOM   8188  C CD    . PRO C 1 6   ? -22.050 -27.542 -57.608  1.00 85.59  ? 6   PRO C CD    1 
ATOM   8189  N N     . GLU C 1 7   ? -17.727 -27.308 -58.894  1.00 90.90  ? 7   GLU C N     1 
ATOM   8190  C CA    . GLU C 1 7   ? -16.445 -27.912 -58.555  1.00 99.80  ? 7   GLU C CA    1 
ATOM   8191  C C     . GLU C 1 7   ? -16.273 -28.016 -57.039  1.00 84.51  ? 7   GLU C C     1 
ATOM   8192  O O     . GLU C 1 7   ? -16.300 -26.999 -56.354  1.00 89.94  ? 7   GLU C O     1 
ATOM   8193  C CB    . GLU C 1 7   ? -15.329 -27.037 -59.141  1.00 108.26 ? 7   GLU C CB    1 
ATOM   8194  C CG    . GLU C 1 7   ? -13.971 -27.711 -59.189  1.00 118.30 ? 7   GLU C CG    1 
ATOM   8195  C CD    . GLU C 1 7   ? -13.717 -28.565 -60.420  1.00 127.22 ? 7   GLU C CD    1 
ATOM   8196  O OE1   . GLU C 1 7   ? -14.590 -28.587 -61.323  1.00 123.51 ? 7   GLU C OE1   1 
ATOM   8197  O OE2   . GLU C 1 7   ? -12.635 -29.204 -60.476  1.00 121.11 ? 7   GLU C OE2   1 
ATOM   8198  N N     . GLY C 1 8   ? -16.078 -29.240 -56.528  1.00 74.37  ? 8   GLY C N     1 
ATOM   8199  C CA    . GLY C 1 8   ? -15.838 -29.467 -55.105  1.00 75.90  ? 8   GLY C CA    1 
ATOM   8200  C C     . GLY C 1 8   ? -17.055 -29.970 -54.307  1.00 73.26  ? 8   GLY C C     1 
ATOM   8201  O O     . GLY C 1 8   ? -16.880 -30.449 -53.188  1.00 72.52  ? 8   GLY C O     1 
ATOM   8202  N N     . VAL C 1 9   ? -18.273 -29.903 -54.875  1.00 68.65  ? 9   VAL C N     1 
ATOM   8203  C CA    . VAL C 1 9   ? -19.498 -30.170 -54.130  1.00 73.20  ? 9   VAL C CA    1 
ATOM   8204  C C     . VAL C 1 9   ? -20.163 -31.475 -54.573  1.00 79.12  ? 9   VAL C C     1 
ATOM   8205  O O     . VAL C 1 9   ? -20.435 -31.668 -55.755  1.00 71.03  ? 9   VAL C O     1 
ATOM   8206  C CB    . VAL C 1 9   ? -20.485 -29.009 -54.309  1.00 70.99  ? 9   VAL C CB    1 
ATOM   8207  C CG1   . VAL C 1 9   ? -21.660 -29.137 -53.352  1.00 76.89  ? 9   VAL C CG1   1 
ATOM   8208  C CG2   . VAL C 1 9   ? -19.794 -27.668 -54.151  1.00 70.27  ? 9   VAL C CG2   1 
ATOM   8209  N N     . SER C 1 10  ? -20.527 -32.311 -53.591  1.00 78.71  ? 10  SER C N     1 
ATOM   8210  C CA    . SER C 1 10  ? -21.151 -33.602 -53.844  1.00 80.78  ? 10  SER C CA    1 
ATOM   8211  C C     . SER C 1 10  ? -22.616 -33.424 -54.257  1.00 83.18  ? 10  SER C C     1 
ATOM   8212  O O     . SER C 1 10  ? -23.101 -32.304 -54.381  1.00 86.63  ? 10  SER C O     1 
ATOM   8213  C CB    . SER C 1 10  ? -21.027 -34.500 -52.622  1.00 82.37  ? 10  SER C CB    1 
ATOM   8214  O OG    . SER C 1 10  ? -22.256 -34.572 -51.919  1.00 80.30  ? 10  SER C OG    1 
ATOM   8215  N N     . ALA C 1 11  ? -23.326 -34.535 -54.491  1.00 88.34  ? 11  ALA C N     1 
ATOM   8216  C CA    . ALA C 1 11  ? -24.762 -34.476 -54.732  1.00 92.40  ? 11  ALA C CA    1 
ATOM   8217  C C     . ALA C 1 11  ? -25.525 -34.620 -53.414  1.00 90.24  ? 11  ALA C C     1 
ATOM   8218  O O     . ALA C 1 11  ? -26.620 -34.073 -53.283  1.00 72.84  ? 11  ALA C O     1 
ATOM   8219  C CB    . ALA C 1 11  ? -25.192 -35.526 -55.726  1.00 83.03  ? 11  ALA C CB    1 
ATOM   8220  N N     . GLU C 1 12  ? -24.952 -35.354 -52.447  1.00 90.69  ? 12  GLU C N     1 
ATOM   8221  C CA    . GLU C 1 12  ? -25.560 -35.468 -51.126  1.00 98.53  ? 12  GLU C CA    1 
ATOM   8222  C C     . GLU C 1 12  ? -25.588 -34.093 -50.462  1.00 97.96  ? 12  GLU C C     1 
ATOM   8223  O O     . GLU C 1 12  ? -26.567 -33.744 -49.802  1.00 91.89  ? 12  GLU C O     1 
ATOM   8224  C CB    . GLU C 1 12  ? -24.820 -36.457 -50.216  1.00 109.78 ? 12  GLU C CB    1 
ATOM   8225  C CG    . GLU C 1 12  ? -25.236 -37.915 -50.390  1.00 127.27 ? 12  GLU C CG    1 
ATOM   8226  C CD    . GLU C 1 12  ? -24.384 -38.736 -51.348  1.00 134.18 ? 12  GLU C CD    1 
ATOM   8227  O OE1   . GLU C 1 12  ? -24.893 -39.111 -52.431  1.00 123.19 ? 12  GLU C OE1   1 
ATOM   8228  O OE2   . GLU C 1 12  ? -23.214 -39.019 -50.997  1.00 123.88 ? 12  GLU C OE2   1 
ATOM   8229  N N     . ALA C 1 13  ? -24.496 -33.335 -50.655  1.00 94.67  ? 13  ALA C N     1 
ATOM   8230  C CA    . ALA C 1 13  ? -24.315 -32.016 -50.069  1.00 85.40  ? 13  ALA C CA    1 
ATOM   8231  C C     . ALA C 1 13  ? -25.307 -31.024 -50.679  1.00 84.33  ? 13  ALA C C     1 
ATOM   8232  O O     . ALA C 1 13  ? -26.056 -30.362 -49.968  1.00 90.13  ? 13  ALA C O     1 
ATOM   8233  C CB    . ALA C 1 13  ? -22.885 -31.568 -50.270  1.00 80.71  ? 13  ALA C CB    1 
ATOM   8234  N N     . MET C 1 14  ? -25.332 -30.952 -52.010  1.00 78.89  ? 14  MET C N     1 
ATOM   8235  C CA    . MET C 1 14  ? -26.210 -30.040 -52.718  1.00 77.03  ? 14  MET C CA    1 
ATOM   8236  C C     . MET C 1 14  ? -27.668 -30.356 -52.393  1.00 76.25  ? 14  MET C C     1 
ATOM   8237  O O     . MET C 1 14  ? -28.517 -29.466 -52.359  1.00 78.84  ? 14  MET C O     1 
ATOM   8238  C CB    . MET C 1 14  ? -25.973 -30.142 -54.231  1.00 75.32  ? 14  MET C CB    1 
ATOM   8239  C CG    . MET C 1 14  ? -26.870 -29.240 -55.079  1.00 78.11  ? 14  MET C CG    1 
ATOM   8240  S SD    . MET C 1 14  ? -26.675 -27.455 -54.768  1.00 72.27  ? 14  MET C SD    1 
ATOM   8241  C CE    . MET C 1 14  ? -25.129 -27.106 -55.608  1.00 76.25  ? 14  MET C CE    1 
ATOM   8242  N N     . SER C 1 15  ? -27.962 -31.633 -52.160  1.00 85.91  ? 15  SER C N     1 
ATOM   8243  C CA    . SER C 1 15  ? -29.337 -32.054 -51.955  1.00 88.02  ? 15  SER C CA    1 
ATOM   8244  C C     . SER C 1 15  ? -29.810 -31.634 -50.565  1.00 79.73  ? 15  SER C C     1 
ATOM   8245  O O     . SER C 1 15  ? -30.936 -31.178 -50.419  1.00 79.10  ? 15  SER C O     1 
ATOM   8246  C CB    . SER C 1 15  ? -29.481 -33.540 -52.177  1.00 83.23  ? 15  SER C CB    1 
ATOM   8247  O OG    . SER C 1 15  ? -30.804 -33.856 -52.553  1.00 88.01  ? 15  SER C OG    1 
ATOM   8248  N N     . SER C 1 16  ? -28.942 -31.782 -49.555  1.00 73.64  ? 16  SER C N     1 
ATOM   8249  C CA    . SER C 1 16  ? -29.303 -31.495 -48.174  1.00 84.25  ? 16  SER C CA    1 
ATOM   8250  C C     . SER C 1 16  ? -29.315 -29.987 -47.912  1.00 88.34  ? 16  SER C C     1 
ATOM   8251  O O     . SER C 1 16  ? -30.002 -29.503 -47.007  1.00 74.08  ? 16  SER C O     1 
ATOM   8252  C CB    . SER C 1 16  ? -28.373 -32.202 -47.233  1.00 84.73  ? 16  SER C CB    1 
ATOM   8253  O OG    . SER C 1 16  ? -28.226 -33.555 -47.630  1.00 84.14  ? 16  SER C OG    1 
ATOM   8254  N N     . ALA C 1 17  ? -28.549 -29.248 -48.720  1.00 83.88  ? 17  ALA C N     1 
ATOM   8255  C CA    . ALA C 1 17  ? -28.561 -27.800 -48.661  1.00 78.46  ? 17  ALA C CA    1 
ATOM   8256  C C     . ALA C 1 17  ? -29.866 -27.245 -49.237  1.00 77.49  ? 17  ALA C C     1 
ATOM   8257  O O     . ALA C 1 17  ? -30.378 -26.260 -48.705  1.00 81.87  ? 17  ALA C O     1 
ATOM   8258  C CB    . ALA C 1 17  ? -27.345 -27.231 -49.348  1.00 76.59  ? 17  ALA C CB    1 
ATOM   8259  N N     . LEU C 1 18  ? -30.417 -27.860 -50.296  1.00 70.80  ? 18  LEU C N     1 
ATOM   8260  C CA    . LEU C 1 18  ? -31.677 -27.389 -50.865  1.00 70.30  ? 18  LEU C CA    1 
ATOM   8261  C C     . LEU C 1 18  ? -32.849 -27.763 -49.960  1.00 71.14  ? 18  LEU C C     1 
ATOM   8262  O O     . LEU C 1 18  ? -33.897 -27.131 -50.005  1.00 72.97  ? 18  LEU C O     1 
ATOM   8263  C CB    . LEU C 1 18  ? -31.861 -27.977 -52.265  1.00 76.29  ? 18  LEU C CB    1 
ATOM   8264  C CG    . LEU C 1 18  ? -30.829 -27.541 -53.308  1.00 81.80  ? 18  LEU C CG    1 
ATOM   8265  C CD1   . LEU C 1 18  ? -30.925 -28.403 -54.563  1.00 77.30  ? 18  LEU C CD1   1 
ATOM   8266  C CD2   . LEU C 1 18  ? -30.987 -26.067 -53.661  1.00 73.24  ? 18  LEU C CD2   1 
ATOM   8267  N N     . ASP C 1 19  ? -32.663 -28.807 -49.148  1.00 78.58  ? 19  ASP C N     1 
ATOM   8268  C CA    . ASP C 1 19  ? -33.625 -29.187 -48.127  1.00 87.76  ? 19  ASP C CA    1 
ATOM   8269  C C     . ASP C 1 19  ? -33.730 -28.071 -47.094  1.00 77.34  ? 19  ASP C C     1 
ATOM   8270  O O     . ASP C 1 19  ? -34.819 -27.599 -46.775  1.00 70.73  ? 19  ASP C O     1 
ATOM   8271  C CB    . ASP C 1 19  ? -33.222 -30.490 -47.421  1.00 93.81  ? 19  ASP C CB    1 
ATOM   8272  C CG    . ASP C 1 19  ? -33.779 -31.758 -48.050  1.00 96.19  ? 19  ASP C CG    1 
ATOM   8273  O OD1   . ASP C 1 19  ? -33.501 -32.012 -49.253  1.00 78.00  ? 19  ASP C OD1   1 
ATOM   8274  O OD2   . ASP C 1 19  ? -34.485 -32.490 -47.324  1.00 102.57 ? 19  ASP C OD2   1 
ATOM   8275  N N     . ARG C 1 20  ? -32.568 -27.671 -46.568  1.00 74.56  ? 20  ARG C N     1 
ATOM   8276  C CA    . ARG C 1 20  ? -32.522 -26.732 -45.463  1.00 68.03  ? 20  ARG C CA    1 
ATOM   8277  C C     . ARG C 1 20  ? -32.953 -25.353 -45.966  1.00 60.26  ? 20  ARG C C     1 
ATOM   8278  O O     . ARG C 1 20  ? -33.602 -24.627 -45.223  1.00 62.41  ? 20  ARG C O     1 
ATOM   8279  C CB    . ARG C 1 20  ? -31.150 -26.801 -44.779  1.00 73.95  ? 20  ARG C CB    1 
ATOM   8280  C CG    . ARG C 1 20  ? -31.215 -26.857 -43.252  1.00 82.27  ? 20  ARG C CG    1 
ATOM   8281  C CD    . ARG C 1 20  ? -29.848 -27.187 -42.680  1.00 92.11  ? 20  ARG C CD    1 
ATOM   8282  N NE    . ARG C 1 20  ? -29.848 -27.797 -41.359  1.00 102.70 ? 20  ARG C NE    1 
ATOM   8283  C CZ    . ARG C 1 20  ? -28.840 -28.513 -40.852  1.00 106.76 ? 20  ARG C CZ    1 
ATOM   8284  N NH1   . ARG C 1 20  ? -27.701 -28.625 -41.517  1.00 102.95 ? 20  ARG C NH1   1 
ATOM   8285  N NH2   . ARG C 1 20  ? -28.973 -29.123 -39.683  1.00 96.70  ? 20  ARG C NH2   1 
ATOM   8286  N N     . PHE C 1 21  ? -32.667 -25.028 -47.241  1.00 57.21  ? 21  PHE C N     1 
ATOM   8287  C CA    . PHE C 1 21  ? -33.158 -23.809 -47.871  1.00 52.07  ? 21  PHE C CA    1 
ATOM   8288  C C     . PHE C 1 21  ? -34.677 -23.824 -47.861  1.00 61.29  ? 21  PHE C C     1 
ATOM   8289  O O     . PHE C 1 21  ? -35.302 -22.824 -47.522  1.00 68.92  ? 21  PHE C O     1 
ATOM   8290  C CB    . PHE C 1 21  ? -32.685 -23.626 -49.324  1.00 54.17  ? 21  PHE C CB    1 
ATOM   8291  C CG    . PHE C 1 21  ? -31.205 -23.378 -49.560  1.00 53.51  ? 21  PHE C CG    1 
ATOM   8292  C CD1   . PHE C 1 21  ? -30.305 -23.197 -48.520  1.00 50.67  ? 21  PHE C CD1   1 
ATOM   8293  C CD2   . PHE C 1 21  ? -30.698 -23.363 -50.851  1.00 57.92  ? 21  PHE C CD2   1 
ATOM   8294  C CE1   . PHE C 1 21  ? -28.954 -23.003 -48.770  1.00 54.97  ? 21  PHE C CE1   1 
ATOM   8295  C CE2   . PHE C 1 21  ? -29.343 -23.173 -51.099  1.00 58.86  ? 21  PHE C CE2   1 
ATOM   8296  C CZ    . PHE C 1 21  ? -28.471 -22.994 -50.057  1.00 52.72  ? 21  PHE C CZ    1 
ATOM   8297  N N     . ALA C 1 22  ? -35.262 -24.969 -48.220  1.00 72.55  ? 22  ALA C N     1 
ATOM   8298  C CA    . ALA C 1 22  ? -36.706 -25.083 -48.325  1.00 73.80  ? 22  ALA C CA    1 
ATOM   8299  C C     . ALA C 1 22  ? -37.352 -24.903 -46.954  1.00 59.82  ? 22  ALA C C     1 
ATOM   8300  O O     . ALA C 1 22  ? -38.374 -24.246 -46.859  1.00 62.66  ? 22  ALA C O     1 
ATOM   8301  C CB    . ALA C 1 22  ? -37.081 -26.398 -48.959  1.00 83.43  ? 22  ALA C CB    1 
ATOM   8302  N N     . ARG C 1 23  ? -36.747 -25.432 -45.889  1.00 62.84  ? 23  ARG C N     1 
ATOM   8303  C CA    . ARG C 1 23  ? -37.265 -25.182 -44.550  1.00 73.60  ? 23  ARG C CA    1 
ATOM   8304  C C     . ARG C 1 23  ? -37.257 -23.679 -44.269  1.00 72.33  ? 23  ARG C C     1 
ATOM   8305  O O     . ARG C 1 23  ? -38.188 -23.161 -43.666  1.00 77.15  ? 23  ARG C O     1 
ATOM   8306  C CB    . ARG C 1 23  ? -36.457 -25.915 -43.469  1.00 84.08  ? 23  ARG C CB    1 
ATOM   8307  C CG    . ARG C 1 23  ? -36.582 -27.432 -43.516  1.00 97.23  ? 23  ARG C CG    1 
ATOM   8308  C CD    . ARG C 1 23  ? -35.603 -28.182 -42.623  1.00 109.21 ? 23  ARG C CD    1 
ATOM   8309  N NE    . ARG C 1 23  ? -35.119 -29.408 -43.267  1.00 122.26 ? 23  ARG C NE    1 
ATOM   8310  C CZ    . ARG C 1 23  ? -34.229 -30.272 -42.764  1.00 118.94 ? 23  ARG C CZ    1 
ATOM   8311  N NH1   . ARG C 1 23  ? -33.875 -30.236 -41.487  1.00 112.95 ? 23  ARG C NH1   1 
ATOM   8312  N NH2   . ARG C 1 23  ? -33.721 -31.208 -43.550  1.00 107.60 ? 23  ARG C NH2   1 
ATOM   8313  N N     . ILE C 1 24  ? -36.200 -22.982 -44.702  1.00 66.32  ? 24  ILE C N     1 
ATOM   8314  C CA    . ILE C 1 24  ? -36.021 -21.576 -44.370  1.00 60.46  ? 24  ILE C CA    1 
ATOM   8315  C C     . ILE C 1 24  ? -37.047 -20.731 -45.111  1.00 57.55  ? 24  ILE C C     1 
ATOM   8316  O O     . ILE C 1 24  ? -37.689 -19.892 -44.492  1.00 67.86  ? 24  ILE C O     1 
ATOM   8317  C CB    . ILE C 1 24  ? -34.590 -21.080 -44.671  1.00 55.73  ? 24  ILE C CB    1 
ATOM   8318  C CG1   . ILE C 1 24  ? -33.534 -21.765 -43.794  1.00 52.49  ? 24  ILE C CG1   1 
ATOM   8319  C CG2   . ILE C 1 24  ? -34.528 -19.564 -44.557  1.00 43.76  ? 24  ILE C CG2   1 
ATOM   8320  C CD1   . ILE C 1 24  ? -32.161 -21.845 -44.443  1.00 57.35  ? 24  ILE C CD1   1 
ATOM   8321  N N     . VAL C 1 25  ? -37.175 -20.911 -46.429  1.00 56.03  ? 25  VAL C N     1 
ATOM   8322  C CA    . VAL C 1 25  ? -37.934 -19.954 -47.218  1.00 56.75  ? 25  VAL C CA    1 
ATOM   8323  C C     . VAL C 1 25  ? -39.321 -20.486 -47.536  1.00 58.77  ? 25  VAL C C     1 
ATOM   8324  O O     . VAL C 1 25  ? -40.122 -19.732 -48.060  1.00 57.60  ? 25  VAL C O     1 
ATOM   8325  C CB    . VAL C 1 25  ? -37.198 -19.569 -48.511  1.00 63.35  ? 25  VAL C CB    1 
ATOM   8326  C CG1   . VAL C 1 25  ? -35.868 -18.875 -48.212  1.00 66.85  ? 25  VAL C CG1   1 
ATOM   8327  C CG2   . VAL C 1 25  ? -37.002 -20.762 -49.433  1.00 66.03  ? 25  VAL C CG2   1 
ATOM   8328  N N     . GLY C 1 26  ? -39.589 -21.766 -47.236  1.00 68.17  ? 26  GLY C N     1 
ATOM   8329  C CA    . GLY C 1 26  ? -40.734 -22.472 -47.801  1.00 76.69  ? 26  GLY C CA    1 
ATOM   8330  C C     . GLY C 1 26  ? -40.398 -23.124 -49.145  1.00 82.14  ? 26  GLY C C     1 
ATOM   8331  O O     . GLY C 1 26  ? -39.726 -22.521 -49.980  1.00 76.64  ? 26  GLY C O     1 
ATOM   8332  N N     . ALA C 1 27  ? -40.894 -24.352 -49.363  1.00 86.21  ? 27  ALA C N     1 
ATOM   8333  C CA    . ALA C 1 27  ? -40.474 -25.175 -50.493  1.00 91.25  ? 27  ALA C CA    1 
ATOM   8334  C C     . ALA C 1 27  ? -40.852 -24.543 -51.838  1.00 80.18  ? 27  ALA C C     1 
ATOM   8335  O O     . ALA C 1 27  ? -40.258 -24.903 -52.850  1.00 91.71  ? 27  ALA C O     1 
ATOM   8336  C CB    . ALA C 1 27  ? -41.039 -26.576 -50.359  1.00 93.31  ? 27  ALA C CB    1 
ATOM   8337  N N     . ASP C 1 28  ? -41.783 -23.575 -51.847  1.00 64.19  ? 28  ASP C N     1 
ATOM   8338  C CA    . ASP C 1 28  ? -42.257 -22.935 -53.068  1.00 68.27  ? 28  ASP C CA    1 
ATOM   8339  C C     . ASP C 1 28  ? -41.283 -21.867 -53.585  1.00 67.89  ? 28  ASP C C     1 
ATOM   8340  O O     . ASP C 1 28  ? -41.492 -21.305 -54.664  1.00 60.23  ? 28  ASP C O     1 
ATOM   8341  C CB    . ASP C 1 28  ? -43.647 -22.322 -52.852  1.00 74.73  ? 28  ASP C CB    1 
ATOM   8342  C CG    . ASP C 1 28  ? -44.646 -23.304 -52.266  1.00 81.49  ? 28  ASP C CG    1 
ATOM   8343  O OD1   . ASP C 1 28  ? -44.201 -24.222 -51.562  1.00 102.28 ? 28  ASP C OD1   1 
ATOM   8344  O OD2   . ASP C 1 28  ? -45.851 -23.174 -52.550  1.00 78.50  ? 28  ASP C OD2   1 
ATOM   8345  N N     . TRP C 1 29  ? -40.223 -21.577 -52.816  1.00 67.66  ? 29  TRP C N     1 
ATOM   8346  C CA    . TRP C 1 29  ? -39.285 -20.513 -53.143  1.00 61.38  ? 29  TRP C CA    1 
ATOM   8347  C C     . TRP C 1 29  ? -37.858 -21.045 -53.341  1.00 64.64  ? 29  TRP C C     1 
ATOM   8348  O O     . TRP C 1 29  ? -36.930 -20.253 -53.355  1.00 51.51  ? 29  TRP C O     1 
ATOM   8349  C CB    . TRP C 1 29  ? -39.347 -19.445 -52.041  1.00 58.51  ? 29  TRP C CB    1 
ATOM   8350  C CG    . TRP C 1 29  ? -40.704 -18.835 -51.871  1.00 54.80  ? 29  TRP C CG    1 
ATOM   8351  C CD1   . TRP C 1 29  ? -41.522 -18.949 -50.785  1.00 52.14  ? 29  TRP C CD1   1 
ATOM   8352  C CD2   . TRP C 1 29  ? -41.426 -18.039 -52.831  1.00 53.46  ? 29  TRP C CD2   1 
ATOM   8353  N NE1   . TRP C 1 29  ? -42.697 -18.276 -50.995  1.00 51.27  ? 29  TRP C NE1   1 
ATOM   8354  C CE2   . TRP C 1 29  ? -42.662 -17.691 -52.232  1.00 51.28  ? 29  TRP C CE2   1 
ATOM   8355  C CE3   . TRP C 1 29  ? -41.135 -17.552 -54.112  1.00 50.16  ? 29  TRP C CE3   1 
ATOM   8356  C CZ2   . TRP C 1 29  ? -43.613 -16.904 -52.878  1.00 51.97  ? 29  TRP C CZ2   1 
ATOM   8357  C CZ3   . TRP C 1 29  ? -42.074 -16.765 -54.746  1.00 53.57  ? 29  TRP C CZ3   1 
ATOM   8358  C CH2   . TRP C 1 29  ? -43.304 -16.468 -54.150  1.00 54.64  ? 29  TRP C CH2   1 
ATOM   8359  N N     . VAL C 1 30  ? -37.682 -22.376 -53.453  1.00 74.37  ? 30  VAL C N     1 
ATOM   8360  C CA    . VAL C 1 30  ? -36.499 -22.985 -54.048  1.00 71.39  ? 30  VAL C CA    1 
ATOM   8361  C C     . VAL C 1 30  ? -36.880 -23.451 -55.451  1.00 63.77  ? 30  VAL C C     1 
ATOM   8362  O O     . VAL C 1 30  ? -38.002 -23.865 -55.662  1.00 66.57  ? 30  VAL C O     1 
ATOM   8363  C CB    . VAL C 1 30  ? -35.965 -24.166 -53.220  1.00 69.97  ? 30  VAL C CB    1 
ATOM   8364  C CG1   . VAL C 1 30  ? -34.551 -24.545 -53.642  1.00 70.43  ? 30  VAL C CG1   1 
ATOM   8365  C CG2   . VAL C 1 30  ? -36.012 -23.889 -51.730  1.00 75.60  ? 30  VAL C CG2   1 
ATOM   8366  N N     . PHE C 1 31  ? -35.962 -23.357 -56.415  1.00 71.83  ? 31  PHE C N     1 
ATOM   8367  C CA    . PHE C 1 31  ? -36.297 -23.560 -57.818  1.00 73.11  ? 31  PHE C CA    1 
ATOM   8368  C C     . PHE C 1 31  ? -35.200 -24.376 -58.487  1.00 80.07  ? 31  PHE C C     1 
ATOM   8369  O O     . PHE C 1 31  ? -34.042 -23.975 -58.464  1.00 75.05  ? 31  PHE C O     1 
ATOM   8370  C CB    . PHE C 1 31  ? -36.475 -22.219 -58.536  1.00 78.29  ? 31  PHE C CB    1 
ATOM   8371  C CG    . PHE C 1 31  ? -37.537 -21.328 -57.936  1.00 84.46  ? 31  PHE C CG    1 
ATOM   8372  C CD1   . PHE C 1 31  ? -38.877 -21.681 -57.989  1.00 88.73  ? 31  PHE C CD1   1 
ATOM   8373  C CD2   . PHE C 1 31  ? -37.199 -20.152 -57.286  1.00 85.16  ? 31  PHE C CD2   1 
ATOM   8374  C CE1   . PHE C 1 31  ? -39.853 -20.863 -57.437  1.00 91.00  ? 31  PHE C CE1   1 
ATOM   8375  C CE2   . PHE C 1 31  ? -38.175 -19.344 -56.721  1.00 94.06  ? 31  PHE C CE2   1 
ATOM   8376  C CZ    . PHE C 1 31  ? -39.502 -19.697 -56.800  1.00 90.66  ? 31  PHE C CZ    1 
ATOM   8377  N N     . THR C 1 32  ? -35.596 -25.515 -59.078  1.00 100.90 ? 32  THR C N     1 
ATOM   8378  C CA    . THR C 1 32  ? -34.690 -26.479 -59.691  1.00 97.00  ? 32  THR C CA    1 
ATOM   8379  C C     . THR C 1 32  ? -35.190 -26.783 -61.105  1.00 95.21  ? 32  THR C C     1 
ATOM   8380  O O     . THR C 1 32  ? -35.891 -25.956 -61.680  1.00 88.02  ? 32  THR C O     1 
ATOM   8381  C CB    . THR C 1 32  ? -34.598 -27.739 -58.819  1.00 94.65  ? 32  THR C CB    1 
ATOM   8382  O OG1   . THR C 1 32  ? -35.868 -28.390 -58.902  1.00 91.15  ? 32  THR C OG1   1 
ATOM   8383  C CG2   . THR C 1 32  ? -34.244 -27.446 -57.375  1.00 92.29  ? 32  THR C CG2   1 
ATOM   8384  N N     . GLU C 1 33  ? -34.801 -27.952 -61.653  1.00 110.21 ? 33  GLU C N     1 
ATOM   8385  C CA    . GLU C 1 33  ? -35.417 -28.549 -62.835  1.00 104.58 ? 33  GLU C CA    1 
ATOM   8386  C C     . GLU C 1 33  ? -35.403 -27.516 -63.966  1.00 109.29 ? 33  GLU C C     1 
ATOM   8387  O O     . GLU C 1 33  ? -34.385 -26.852 -64.172  1.00 89.88  ? 33  GLU C O     1 
ATOM   8388  C CB    . GLU C 1 33  ? -36.815 -29.104 -62.499  1.00 109.68 ? 33  GLU C CB    1 
ATOM   8389  C CG    . GLU C 1 33  ? -36.841 -30.270 -61.503  1.00 111.14 ? 33  GLU C CG    1 
ATOM   8390  C CD    . GLU C 1 33  ? -36.645 -31.672 -62.075  1.00 112.75 ? 33  GLU C CD    1 
ATOM   8391  O OE1   . GLU C 1 33  ? -35.638 -32.322 -61.722  1.00 101.46 ? 33  GLU C OE1   1 
ATOM   8392  O OE2   . GLU C 1 33  ? -37.508 -32.134 -62.859  1.00 93.77  ? 33  GLU C OE2   1 
ATOM   8393  N N     . ASP C 1 34  ? -36.538 -27.359 -64.675  1.00 127.33 ? 34  ASP C N     1 
ATOM   8394  C CA    . ASP C 1 34  ? -36.642 -26.436 -65.801  1.00 139.13 ? 34  ASP C CA    1 
ATOM   8395  C C     . ASP C 1 34  ? -37.371 -25.154 -65.384  1.00 131.46 ? 34  ASP C C     1 
ATOM   8396  O O     . ASP C 1 34  ? -37.853 -24.413 -66.239  1.00 117.73 ? 34  ASP C O     1 
ATOM   8397  C CB    . ASP C 1 34  ? -37.311 -27.096 -67.017  1.00 138.89 ? 34  ASP C CB    1 
ATOM   8398  C CG    . ASP C 1 34  ? -38.799 -27.385 -66.863  1.00 137.71 ? 34  ASP C CG    1 
ATOM   8399  O OD1   . ASP C 1 34  ? -39.289 -27.401 -65.709  1.00 130.14 ? 34  ASP C OD1   1 
ATOM   8400  O OD2   . ASP C 1 34  ? -39.467 -27.570 -67.903  1.00 111.22 ? 34  ASP C OD2   1 
ATOM   8401  N N     . LYS C 1 35  ? -37.431 -24.886 -64.071  1.00 128.66 ? 35  LYS C N     1 
ATOM   8402  C CA    . LYS C 1 35  ? -37.877 -23.603 -63.541  1.00 127.42 ? 35  LYS C CA    1 
ATOM   8403  C C     . LYS C 1 35  ? -36.715 -22.600 -63.528  1.00 130.70 ? 35  LYS C C     1 
ATOM   8404  O O     . LYS C 1 35  ? -36.889 -21.447 -63.135  1.00 119.02 ? 35  LYS C O     1 
ATOM   8405  C CB    . LYS C 1 35  ? -38.464 -23.811 -62.139  1.00 114.77 ? 35  LYS C CB    1 
ATOM   8406  C CG    . LYS C 1 35  ? -39.984 -23.785 -62.042  1.00 107.58 ? 35  LYS C CG    1 
ATOM   8407  C CD    . LYS C 1 35  ? -40.516 -22.435 -61.602  1.00 111.43 ? 35  LYS C CD    1 
ATOM   8408  C CE    . LYS C 1 35  ? -41.995 -22.442 -61.278  1.00 112.30 ? 35  LYS C CE    1 
ATOM   8409  N NZ    . LYS C 1 35  ? -42.800 -22.402 -62.520  1.00 111.57 ? 35  LYS C NZ    1 
ATOM   8410  N N     . ILE C 1 36  ? -35.539 -23.023 -64.011  1.00 126.47 ? 36  ILE C N     1 
ATOM   8411  C CA    . ILE C 1 36  ? -34.305 -22.283 -63.810  1.00 117.60 ? 36  ILE C CA    1 
ATOM   8412  C C     . ILE C 1 36  ? -33.945 -21.454 -65.050  1.00 122.63 ? 36  ILE C C     1 
ATOM   8413  O O     . ILE C 1 36  ? -32.833 -20.929 -65.111  1.00 131.01 ? 36  ILE C O     1 
ATOM   8414  C CB    . ILE C 1 36  ? -33.182 -23.270 -63.408  1.00 111.88 ? 36  ILE C CB    1 
ATOM   8415  C CG1   . ILE C 1 36  ? -32.109 -22.602 -62.547  1.00 111.05 ? 36  ILE C CG1   1 
ATOM   8416  C CG2   . ILE C 1 36  ? -32.572 -23.980 -64.609  1.00 107.88 ? 36  ILE C CG2   1 
ATOM   8417  C CD1   . ILE C 1 36  ? -32.578 -22.267 -61.151  1.00 113.04 ? 36  ILE C CD1   1 
ATOM   8418  N N     . THR C 1 37  ? -34.870 -21.304 -66.020  1.00 117.76 ? 37  THR C N     1 
ATOM   8419  C CA    . THR C 1 37  ? -34.536 -20.699 -67.310  1.00 123.38 ? 37  THR C CA    1 
ATOM   8420  C C     . THR C 1 37  ? -34.671 -19.170 -67.324  1.00 118.78 ? 37  THR C C     1 
ATOM   8421  O O     . THR C 1 37  ? -34.043 -18.532 -68.168  1.00 106.65 ? 37  THR C O     1 
ATOM   8422  C CB    . THR C 1 37  ? -35.330 -21.296 -68.483  1.00 112.37 ? 37  THR C CB    1 
ATOM   8423  O OG1   . THR C 1 37  ? -36.727 -21.191 -68.210  1.00 107.75 ? 37  THR C OG1   1 
ATOM   8424  C CG2   . THR C 1 37  ? -34.946 -22.733 -68.769  1.00 105.44 ? 37  THR C CG2   1 
ATOM   8425  N N     . PRO C 1 38  ? -35.481 -18.508 -66.457  1.00 114.53 ? 38  PRO C N     1 
ATOM   8426  C CA    . PRO C 1 38  ? -35.404 -17.046 -66.316  1.00 104.33 ? 38  PRO C CA    1 
ATOM   8427  C C     . PRO C 1 38  ? -34.078 -16.490 -65.763  1.00 93.18  ? 38  PRO C C     1 
ATOM   8428  O O     . PRO C 1 38  ? -33.808 -15.286 -65.858  1.00 68.04  ? 38  PRO C O     1 
ATOM   8429  C CB    . PRO C 1 38  ? -36.570 -16.716 -65.363  1.00 103.63 ? 38  PRO C CB    1 
ATOM   8430  C CG    . PRO C 1 38  ? -37.491 -17.918 -65.435  1.00 100.89 ? 38  PRO C CG    1 
ATOM   8431  C CD    . PRO C 1 38  ? -36.567 -19.094 -65.649  1.00 106.66 ? 38  PRO C CD    1 
ATOM   8432  N N     . TYR C 1 39  ? -33.235 -17.367 -65.195  1.00 88.42  ? 39  TYR C N     1 
ATOM   8433  C CA    . TYR C 1 39  ? -31.944 -16.965 -64.652  1.00 99.18  ? 39  TYR C CA    1 
ATOM   8434  C C     . TYR C 1 39  ? -30.814 -17.229 -65.653  1.00 96.06  ? 39  TYR C C     1 
ATOM   8435  O O     . TYR C 1 39  ? -29.660 -16.897 -65.377  1.00 86.88  ? 39  TYR C O     1 
ATOM   8436  C CB    . TYR C 1 39  ? -31.707 -17.644 -63.296  1.00 95.90  ? 39  TYR C CB    1 
ATOM   8437  C CG    . TYR C 1 39  ? -32.797 -17.369 -62.293  1.00 99.02  ? 39  TYR C CG    1 
ATOM   8438  C CD1   . TYR C 1 39  ? -32.928 -16.128 -61.681  1.00 100.13 ? 39  TYR C CD1   1 
ATOM   8439  C CD2   . TYR C 1 39  ? -33.755 -18.331 -62.014  1.00 113.92 ? 39  TYR C CD2   1 
ATOM   8440  C CE1   . TYR C 1 39  ? -33.959 -15.865 -60.788  1.00 97.87  ? 39  TYR C CE1   1 
ATOM   8441  C CE2   . TYR C 1 39  ? -34.790 -18.087 -61.124  1.00 110.85 ? 39  TYR C CE2   1 
ATOM   8442  C CZ    . TYR C 1 39  ? -34.891 -16.853 -60.508  1.00 99.30  ? 39  TYR C CZ    1 
ATOM   8443  O OH    . TYR C 1 39  ? -35.933 -16.677 -59.640  1.00 83.21  ? 39  TYR C OH    1 
ATOM   8444  N N     . GLU C 1 40  ? -31.143 -17.812 -66.816  1.00 95.90  ? 40  GLU C N     1 
ATOM   8445  C CA    . GLU C 1 40  ? -30.181 -17.953 -67.901  1.00 98.30  ? 40  GLU C CA    1 
ATOM   8446  C C     . GLU C 1 40  ? -29.868 -16.568 -68.469  1.00 90.28  ? 40  GLU C C     1 
ATOM   8447  O O     . GLU C 1 40  ? -30.777 -15.766 -68.671  1.00 88.24  ? 40  GLU C O     1 
ATOM   8448  C CB    . GLU C 1 40  ? -30.708 -18.903 -68.988  1.00 89.39  ? 40  GLU C CB    1 
ATOM   8449  C CG    . GLU C 1 40  ? -30.800 -20.355 -68.532  1.00 83.77  ? 40  GLU C CG    1 
ATOM   8450  C CD    . GLU C 1 40  ? -29.475 -20.999 -68.146  1.00 81.64  ? 40  GLU C CD    1 
ATOM   8451  O OE1   . GLU C 1 40  ? -28.429 -20.436 -68.514  1.00 72.20  ? 40  GLU C OE1   1 
ATOM   8452  O OE2   . GLU C 1 40  ? -29.481 -22.054 -67.456  1.00 82.19  ? 40  GLU C OE2   1 
ATOM   8453  N N     . ASP C 1 41  ? -28.573 -16.293 -68.684  1.00 84.39  ? 41  ASP C N     1 
ATOM   8454  C CA    . ASP C 1 41  ? -28.114 -15.128 -69.429  1.00 91.48  ? 41  ASP C CA    1 
ATOM   8455  C C     . ASP C 1 41  ? -29.038 -14.932 -70.640  1.00 104.13 ? 41  ASP C C     1 
ATOM   8456  O O     . ASP C 1 41  ? -29.009 -15.748 -71.568  1.00 92.85  ? 41  ASP C O     1 
ATOM   8457  C CB    . ASP C 1 41  ? -26.635 -15.329 -69.792  1.00 92.50  ? 41  ASP C CB    1 
ATOM   8458  C CG    . ASP C 1 41  ? -25.900 -14.176 -70.465  1.00 92.01  ? 41  ASP C CG    1 
ATOM   8459  O OD1   . ASP C 1 41  ? -26.490 -13.067 -70.607  1.00 79.54  ? 41  ASP C OD1   1 
ATOM   8460  O OD2   . ASP C 1 41  ? -24.725 -14.406 -70.851  1.00 88.57  ? 41  ASP C OD2   1 
ATOM   8461  N N     . PRO C 1 42  ? -29.916 -13.884 -70.654  1.00 111.98 ? 42  PRO C N     1 
ATOM   8462  C CA    . PRO C 1 42  ? -30.857 -13.674 -71.760  1.00 99.73  ? 42  PRO C CA    1 
ATOM   8463  C C     . PRO C 1 42  ? -30.180 -13.271 -73.073  1.00 101.44 ? 42  PRO C C     1 
ATOM   8464  O O     . PRO C 1 42  ? -30.756 -13.477 -74.136  1.00 114.95 ? 42  PRO C O     1 
ATOM   8465  C CB    . PRO C 1 42  ? -31.806 -12.562 -71.267  1.00 90.12  ? 42  PRO C CB    1 
ATOM   8466  C CG    . PRO C 1 42  ? -31.009 -11.820 -70.207  1.00 96.10  ? 42  PRO C CG    1 
ATOM   8467  C CD    . PRO C 1 42  ? -30.055 -12.842 -69.614  1.00 104.14 ? 42  PRO C CD    1 
ATOM   8468  N N     . TYR C 1 43  ? -28.967 -12.701 -73.004  1.00 93.48  ? 43  TYR C N     1 
ATOM   8469  C CA    . TYR C 1 43  ? -28.153 -12.456 -74.188  1.00 93.99  ? 43  TYR C CA    1 
ATOM   8470  C C     . TYR C 1 43  ? -26.902 -13.338 -74.142  1.00 104.61 ? 43  TYR C C     1 
ATOM   8471  O O     . TYR C 1 43  ? -25.874 -12.926 -73.602  1.00 121.58 ? 43  TYR C O     1 
ATOM   8472  C CB    . TYR C 1 43  ? -27.746 -10.980 -74.278  1.00 93.90  ? 43  TYR C CB    1 
ATOM   8473  C CG    . TYR C 1 43  ? -28.850 -9.950  -74.215  1.00 91.88  ? 43  TYR C CG    1 
ATOM   8474  C CD1   . TYR C 1 43  ? -30.167 -10.231 -74.553  1.00 87.80  ? 43  TYR C CD1   1 
ATOM   8475  C CD2   . TYR C 1 43  ? -28.563 -8.663  -73.793  1.00 91.30  ? 43  TYR C CD2   1 
ATOM   8476  C CE1   . TYR C 1 43  ? -31.153 -9.257  -74.491  1.00 79.07  ? 43  TYR C CE1   1 
ATOM   8477  C CE2   . TYR C 1 43  ? -29.534 -7.680  -73.724  1.00 81.11  ? 43  TYR C CE2   1 
ATOM   8478  C CZ    . TYR C 1 43  ? -30.836 -7.974  -74.074  1.00 83.52  ? 43  TYR C CZ    1 
ATOM   8479  O OH    . TYR C 1 43  ? -31.770 -6.960  -73.986  1.00 93.52  ? 43  TYR C OH    1 
ATOM   8480  N N     . THR C 1 44  ? -26.999 -14.553 -74.713  1.00 113.69 ? 44  THR C N     1 
ATOM   8481  C CA    . THR C 1 44  ? -25.945 -15.566 -74.642  1.00 109.23 ? 44  THR C CA    1 
ATOM   8482  C C     . THR C 1 44  ? -24.748 -15.100 -75.488  1.00 111.08 ? 44  THR C C     1 
ATOM   8483  O O     . THR C 1 44  ? -24.937 -14.433 -76.504  1.00 118.96 ? 44  THR C O     1 
ATOM   8484  C CB    . THR C 1 44  ? -26.512 -16.973 -74.944  1.00 93.13  ? 44  THR C CB    1 
ATOM   8485  O OG1   . THR C 1 44  ? -25.452 -17.874 -75.249  1.00 87.30  ? 44  THR C OG1   1 
ATOM   8486  C CG2   . THR C 1 44  ? -27.460 -17.067 -76.117  1.00 90.67  ? 44  THR C CG2   1 
ATOM   8487  N N     . ILE C 1 45  ? -23.518 -15.405 -75.030  1.00 111.78 ? 45  ILE C N     1 
ATOM   8488  C CA    . ILE C 1 45  ? -22.286 -14.962 -75.686  1.00 117.51 ? 45  ILE C CA    1 
ATOM   8489  C C     . ILE C 1 45  ? -21.360 -16.142 -76.015  1.00 105.77 ? 45  ILE C C     1 
ATOM   8490  O O     . ILE C 1 45  ? -20.666 -16.104 -77.032  1.00 106.19 ? 45  ILE C O     1 
ATOM   8491  C CB    . ILE C 1 45  ? -21.545 -13.894 -74.846  1.00 131.25 ? 45  ILE C CB    1 
ATOM   8492  C CG1   . ILE C 1 45  ? -22.408 -12.645 -74.632  1.00 124.09 ? 45  ILE C CG1   1 
ATOM   8493  C CG2   . ILE C 1 45  ? -20.195 -13.552 -75.479  1.00 132.36 ? 45  ILE C CG2   1 
ATOM   8494  C CD1   . ILE C 1 45  ? -21.679 -11.466 -74.010  1.00 120.89 ? 45  ILE C CD1   1 
ATOM   8495  N N     . SER C 1 46  ? -21.294 -17.159 -75.146  1.00 102.43 ? 46  SER C N     1 
ATOM   8496  C CA    . SER C 1 46  ? -20.435 -18.308 -75.396  1.00 108.31 ? 46  SER C CA    1 
ATOM   8497  C C     . SER C 1 46  ? -21.198 -19.376 -76.176  1.00 114.02 ? 46  SER C C     1 
ATOM   8498  O O     . SER C 1 46  ? -22.422 -19.487 -76.069  1.00 98.56  ? 46  SER C O     1 
ATOM   8499  C CB    . SER C 1 46  ? -19.832 -18.874 -74.121  1.00 107.18 ? 46  SER C CB    1 
ATOM   8500  O OG    . SER C 1 46  ? -20.769 -19.640 -73.384  1.00 99.23  ? 46  SER C OG    1 
ATOM   8501  N N     . ASN C 1 47  ? -20.433 -20.134 -76.976  1.00 126.69 ? 47  ASN C N     1 
ATOM   8502  C CA    . ASN C 1 47  ? -20.925 -21.283 -77.722  1.00 117.77 ? 47  ASN C CA    1 
ATOM   8503  C C     . ASN C 1 47  ? -20.908 -22.519 -76.831  1.00 106.49 ? 47  ASN C C     1 
ATOM   8504  O O     . ASN C 1 47  ? -21.463 -23.550 -77.201  1.00 101.85 ? 47  ASN C O     1 
ATOM   8505  C CB    . ASN C 1 47  ? -20.105 -21.528 -78.995  1.00 111.98 ? 47  ASN C CB    1 
ATOM   8506  C CG    . ASN C 1 47  ? -20.356 -20.477 -80.055  1.00 102.40 ? 47  ASN C CG    1 
ATOM   8507  O OD1   . ASN C 1 47  ? -21.507 -20.157 -80.344  1.00 95.00  ? 47  ASN C OD1   1 
ATOM   8508  N ND2   . ASN C 1 47  ? -19.298 -19.919 -80.622  1.00 101.49 ? 47  ASN C ND2   1 
ATOM   8509  N N     . ASP C 1 48  ? -20.241 -22.411 -75.676  1.00 113.85 ? 48  ASP C N     1 
ATOM   8510  C CA    . ASP C 1 48  ? -20.240 -23.471 -74.681  1.00 117.72 ? 48  ASP C CA    1 
ATOM   8511  C C     . ASP C 1 48  ? -21.523 -23.328 -73.861  1.00 115.98 ? 48  ASP C C     1 
ATOM   8512  O O     . ASP C 1 48  ? -21.868 -22.229 -73.435  1.00 111.54 ? 48  ASP C O     1 
ATOM   8513  C CB    . ASP C 1 48  ? -18.961 -23.421 -73.833  1.00 112.40 ? 48  ASP C CB    1 
ATOM   8514  C CG    . ASP C 1 48  ? -18.396 -24.774 -73.413  1.00 107.04 ? 48  ASP C CG    1 
ATOM   8515  O OD1   . ASP C 1 48  ? -19.183 -25.661 -73.009  1.00 115.00 ? 48  ASP C OD1   1 
ATOM   8516  O OD2   . ASP C 1 48  ? -17.164 -24.921 -73.456  1.00 86.69  ? 48  ASP C OD2   1 
ATOM   8517  N N     . GLU C 1 49  ? -22.235 -24.447 -73.676  1.00 118.79 ? 49  GLU C N     1 
ATOM   8518  C CA    . GLU C 1 49  ? -23.498 -24.468 -72.955  1.00 116.30 ? 49  GLU C CA    1 
ATOM   8519  C C     . GLU C 1 49  ? -23.303 -25.122 -71.586  1.00 127.50 ? 49  GLU C C     1 
ATOM   8520  O O     . GLU C 1 49  ? -24.276 -25.456 -70.912  1.00 129.31 ? 49  GLU C O     1 
ATOM   8521  C CB    . GLU C 1 49  ? -24.545 -25.188 -73.804  1.00 111.28 ? 49  GLU C CB    1 
ATOM   8522  C CG    . GLU C 1 49  ? -24.588 -24.682 -75.236  1.00 109.13 ? 49  GLU C CG    1 
ATOM   8523  C CD    . GLU C 1 49  ? -25.897 -24.927 -75.965  1.00 99.94  ? 49  GLU C CD    1 
ATOM   8524  O OE1   . GLU C 1 49  ? -26.373 -26.078 -75.941  1.00 90.08  ? 49  GLU C OE1   1 
ATOM   8525  O OE2   . GLU C 1 49  ? -26.431 -23.961 -76.556  1.00 88.89  ? 49  GLU C OE2   1 
ATOM   8526  N N     . THR C 1 50  ? -22.035 -25.281 -71.178  1.00 136.64 ? 50  THR C N     1 
ATOM   8527  C CA    . THR C 1 50  ? -21.678 -25.701 -69.830  1.00 127.43 ? 50  THR C CA    1 
ATOM   8528  C C     . THR C 1 50  ? -21.314 -24.490 -68.965  1.00 129.38 ? 50  THR C C     1 
ATOM   8529  O O     . THR C 1 50  ? -20.948 -24.679 -67.809  1.00 134.69 ? 50  THR C O     1 
ATOM   8530  C CB    . THR C 1 50  ? -20.506 -26.693 -69.859  1.00 114.60 ? 50  THR C CB    1 
ATOM   8531  O OG1   . THR C 1 50  ? -19.301 -25.990 -70.173  1.00 96.52  ? 50  THR C OG1   1 
ATOM   8532  C CG2   . THR C 1 50  ? -20.714 -27.812 -70.857  1.00 115.70 ? 50  THR C CG2   1 
ATOM   8533  N N     . GLU C 1 51  ? -21.431 -23.265 -69.518  1.00 123.99 ? 51  GLU C N     1 
ATOM   8534  C CA    . GLU C 1 51  ? -20.941 -22.044 -68.885  1.00 123.01 ? 51  GLU C CA    1 
ATOM   8535  C C     . GLU C 1 51  ? -22.089 -21.094 -68.525  1.00 114.26 ? 51  GLU C C     1 
ATOM   8536  O O     . GLU C 1 51  ? -23.038 -20.955 -69.296  1.00 89.58  ? 51  GLU C O     1 
ATOM   8537  C CB    . GLU C 1 51  ? -19.966 -21.319 -69.815  1.00 124.78 ? 51  GLU C CB    1 
ATOM   8538  C CG    . GLU C 1 51  ? -18.666 -22.069 -70.049  1.00 121.54 ? 51  GLU C CG    1 
ATOM   8539  C CD    . GLU C 1 51  ? -17.579 -21.191 -70.640  1.00 116.57 ? 51  GLU C CD    1 
ATOM   8540  O OE1   . GLU C 1 51  ? -17.864 -20.494 -71.640  1.00 110.61 ? 51  GLU C OE1   1 
ATOM   8541  O OE2   . GLU C 1 51  ? -16.461 -21.197 -70.092  1.00 115.37 ? 51  GLU C OE2   1 
ATOM   8542  N N     . HIS C 1 52  ? -21.967 -20.436 -67.353  1.00 106.16 ? 52  HIS C N     1 
ATOM   8543  C CA    . HIS C 1 52  ? -22.938 -19.478 -66.827  1.00 89.69  ? 52  HIS C CA    1 
ATOM   8544  C C     . HIS C 1 52  ? -24.319 -20.107 -66.618  1.00 89.15  ? 52  HIS C C     1 
ATOM   8545  O O     . HIS C 1 52  ? -25.323 -19.447 -66.886  1.00 86.27  ? 52  HIS C O     1 
ATOM   8546  C CB    . HIS C 1 52  ? -22.993 -18.223 -67.704  1.00 83.46  ? 52  HIS C CB    1 
ATOM   8547  C CG    . HIS C 1 52  ? -21.626 -17.707 -68.000  1.00 89.45  ? 52  HIS C CG    1 
ATOM   8548  N ND1   . HIS C 1 52  ? -20.598 -17.825 -67.086  1.00 90.93  ? 52  HIS C ND1   1 
ATOM   8549  C CD2   . HIS C 1 52  ? -21.092 -17.149 -69.097  1.00 93.75  ? 52  HIS C CD2   1 
ATOM   8550  C CE1   . HIS C 1 52  ? -19.491 -17.311 -67.605  1.00 93.33  ? 52  HIS C CE1   1 
ATOM   8551  N NE2   . HIS C 1 52  ? -19.768 -16.899 -68.829  1.00 101.20 ? 52  HIS C NE2   1 
ATOM   8552  N N     . ARG C 1 53  ? -24.337 -21.357 -66.107  1.00 92.53  ? 53  ARG C N     1 
ATOM   8553  C CA    . ARG C 1 53  ? -25.541 -22.141 -65.835  1.00 93.83  ? 53  ARG C CA    1 
ATOM   8554  C C     . ARG C 1 53  ? -25.742 -22.241 -64.324  1.00 95.66  ? 53  ARG C C     1 
ATOM   8555  O O     . ARG C 1 53  ? -24.845 -22.705 -63.618  1.00 106.84 ? 53  ARG C O     1 
ATOM   8556  C CB    . ARG C 1 53  ? -25.428 -23.589 -66.342  1.00 97.27  ? 53  ARG C CB    1 
ATOM   8557  C CG    . ARG C 1 53  ? -24.842 -23.758 -67.737  1.00 97.26  ? 53  ARG C CG    1 
ATOM   8558  C CD    . ARG C 1 53  ? -25.622 -22.982 -68.780  1.00 104.62 ? 53  ARG C CD    1 
ATOM   8559  N NE    . ARG C 1 53  ? -27.028 -23.368 -68.823  1.00 108.03 ? 53  ARG C NE    1 
ATOM   8560  C CZ    . ARG C 1 53  ? -27.630 -23.924 -69.869  1.00 110.59 ? 53  ARG C CZ    1 
ATOM   8561  N NH1   . ARG C 1 53  ? -26.950 -24.179 -70.971  1.00 118.04 ? 53  ARG C NH1   1 
ATOM   8562  N NH2   . ARG C 1 53  ? -28.918 -24.212 -69.821  1.00 112.28 ? 53  ARG C NH2   1 
ATOM   8563  N N     . PRO C 1 54  ? -26.892 -21.793 -63.766  1.00 76.89  ? 54  PRO C N     1 
ATOM   8564  C CA    . PRO C 1 54  ? -27.146 -21.917 -62.332  1.00 65.56  ? 54  PRO C CA    1 
ATOM   8565  C C     . PRO C 1 54  ? -27.821 -23.236 -61.971  1.00 65.14  ? 54  PRO C C     1 
ATOM   8566  O O     . PRO C 1 54  ? -28.737 -23.668 -62.656  1.00 66.13  ? 54  PRO C O     1 
ATOM   8567  C CB    . PRO C 1 54  ? -28.051 -20.714 -62.056  1.00 67.12  ? 54  PRO C CB    1 
ATOM   8568  C CG    . PRO C 1 54  ? -28.813 -20.499 -63.346  1.00 74.07  ? 54  PRO C CG    1 
ATOM   8569  C CD    . PRO C 1 54  ? -27.950 -21.052 -64.462  1.00 76.48  ? 54  PRO C CD    1 
ATOM   8570  N N     . TYR C 1 55  ? -27.360 -23.879 -60.894  1.00 61.87  ? 55  TYR C N     1 
ATOM   8571  C CA    . TYR C 1 55  ? -27.931 -25.147 -60.490  1.00 64.03  ? 55  TYR C CA    1 
ATOM   8572  C C     . TYR C 1 55  ? -29.345 -24.926 -59.957  1.00 67.92  ? 55  TYR C C     1 
ATOM   8573  O O     . TYR C 1 55  ? -30.264 -25.636 -60.346  1.00 70.71  ? 55  TYR C O     1 
ATOM   8574  C CB    . TYR C 1 55  ? -27.054 -25.855 -59.457  1.00 64.44  ? 55  TYR C CB    1 
ATOM   8575  C CG    . TYR C 1 55  ? -27.477 -27.273 -59.163  1.00 78.44  ? 55  TYR C CG    1 
ATOM   8576  C CD1   . TYR C 1 55  ? -28.535 -27.537 -58.306  1.00 89.88  ? 55  TYR C CD1   1 
ATOM   8577  C CD2   . TYR C 1 55  ? -26.853 -28.359 -59.769  1.00 91.46  ? 55  TYR C CD2   1 
ATOM   8578  C CE1   . TYR C 1 55  ? -28.948 -28.834 -58.033  1.00 96.12  ? 55  TYR C CE1   1 
ATOM   8579  C CE2   . TYR C 1 55  ? -27.259 -29.667 -59.514  1.00 94.13  ? 55  TYR C CE2   1 
ATOM   8580  C CZ    . TYR C 1 55  ? -28.312 -29.904 -58.641  1.00 97.74  ? 55  TYR C CZ    1 
ATOM   8581  O OH    . TYR C 1 55  ? -28.754 -31.169 -58.334  1.00 87.19  ? 55  TYR C OH    1 
ATOM   8582  N N     . ALA C 1 56  ? -29.508 -23.956 -59.045  1.00 67.70  ? 56  ALA C N     1 
ATOM   8583  C CA    . ALA C 1 56  ? -30.798 -23.683 -58.429  1.00 58.86  ? 56  ALA C CA    1 
ATOM   8584  C C     . ALA C 1 56  ? -30.929 -22.195 -58.101  1.00 62.70  ? 56  ALA C C     1 
ATOM   8585  O O     . ALA C 1 56  ? -30.035 -21.403 -58.380  1.00 72.57  ? 56  ALA C O     1 
ATOM   8586  C CB    . ALA C 1 56  ? -30.979 -24.541 -57.202  1.00 52.77  ? 56  ALA C CB    1 
ATOM   8587  N N     . ALA C 1 57  ? -32.099 -21.822 -57.576  1.00 61.43  ? 57  ALA C N     1 
ATOM   8588  C CA    . ALA C 1 57  ? -32.369 -20.477 -57.109  1.00 58.14  ? 57  ALA C CA    1 
ATOM   8589  C C     . ALA C 1 57  ? -33.176 -20.566 -55.824  1.00 61.19  ? 57  ALA C C     1 
ATOM   8590  O O     . ALA C 1 57  ? -33.877 -21.546 -55.594  1.00 58.75  ? 57  ALA C O     1 
ATOM   8591  C CB    . ALA C 1 57  ? -33.102 -19.683 -58.151  1.00 53.06  ? 57  ALA C CB    1 
ATOM   8592  N N     . VAL C 1 58  ? -33.032 -19.540 -54.987  1.00 62.29  ? 58  VAL C N     1 
ATOM   8593  C CA    . VAL C 1 58  ? -33.791 -19.436 -53.757  1.00 59.07  ? 58  VAL C CA    1 
ATOM   8594  C C     . VAL C 1 58  ? -34.162 -17.962 -53.587  1.00 58.01  ? 58  VAL C C     1 
ATOM   8595  O O     . VAL C 1 58  ? -33.354 -17.073 -53.878  1.00 60.79  ? 58  VAL C O     1 
ATOM   8596  C CB    . VAL C 1 58  ? -33.002 -20.045 -52.580  1.00 66.84  ? 58  VAL C CB    1 
ATOM   8597  C CG1   . VAL C 1 58  ? -31.544 -19.615 -52.587  1.00 74.36  ? 58  VAL C CG1   1 
ATOM   8598  C CG2   . VAL C 1 58  ? -33.636 -19.759 -51.231  1.00 62.20  ? 58  VAL C CG2   1 
ATOM   8599  N N     . ALA C 1 59  ? -35.419 -17.716 -53.197  1.00 54.29  ? 59  ALA C N     1 
ATOM   8600  C CA    . ALA C 1 59  ? -35.967 -16.372 -53.120  1.00 55.77  ? 59  ALA C CA    1 
ATOM   8601  C C     . ALA C 1 59  ? -36.401 -16.038 -51.694  1.00 55.70  ? 59  ALA C C     1 
ATOM   8602  O O     . ALA C 1 59  ? -37.584 -16.148 -51.366  1.00 61.49  ? 59  ALA C O     1 
ATOM   8603  C CB    . ALA C 1 59  ? -37.122 -16.235 -54.086  1.00 52.75  ? 59  ALA C CB    1 
ATOM   8604  N N     . PRO C 1 60  ? -35.505 -15.534 -50.812  1.00 60.21  ? 60  PRO C N     1 
ATOM   8605  C CA    . PRO C 1 60  ? -35.884 -15.275 -49.418  1.00 54.68  ? 60  PRO C CA    1 
ATOM   8606  C C     . PRO C 1 60  ? -36.789 -14.059 -49.282  1.00 49.31  ? 60  PRO C C     1 
ATOM   8607  O O     . PRO C 1 60  ? -36.804 -13.194 -50.158  1.00 51.21  ? 60  PRO C O     1 
ATOM   8608  C CB    . PRO C 1 60  ? -34.546 -15.072 -48.709  1.00 49.87  ? 60  PRO C CB    1 
ATOM   8609  C CG    . PRO C 1 60  ? -33.652 -14.522 -49.792  1.00 55.26  ? 60  PRO C CG    1 
ATOM   8610  C CD    . PRO C 1 60  ? -34.110 -15.164 -51.087  1.00 55.33  ? 60  PRO C CD    1 
ATOM   8611  N N     . ALA C 1 61  ? -37.527 -14.019 -48.171  1.00 48.02  ? 61  ALA C N     1 
ATOM   8612  C CA    . ALA C 1 61  ? -38.487 -12.962 -47.897  1.00 56.46  ? 61  ALA C CA    1 
ATOM   8613  C C     . ALA C 1 61  ? -37.886 -11.810 -47.075  1.00 52.19  ? 61  ALA C C     1 
ATOM   8614  O O     . ALA C 1 61  ? -38.510 -10.760 -46.945  1.00 52.66  ? 61  ALA C O     1 
ATOM   8615  C CB    . ALA C 1 61  ? -39.675 -13.579 -47.185  1.00 59.18  ? 61  ALA C CB    1 
ATOM   8616  N N     . SER C 1 62  ? -36.689 -11.984 -46.507  1.00 46.71  ? 62  SER C N     1 
ATOM   8617  C CA    . SER C 1 62  ? -36.202 -11.056 -45.497  1.00 44.05  ? 62  SER C CA    1 
ATOM   8618  C C     . SER C 1 62  ? -34.707 -11.225 -45.261  1.00 45.62  ? 62  SER C C     1 
ATOM   8619  O O     . SER C 1 62  ? -34.104 -12.246 -45.613  1.00 49.21  ? 62  SER C O     1 
ATOM   8620  C CB    . SER C 1 62  ? -36.933 -11.261 -44.194  1.00 47.71  ? 62  SER C CB    1 
ATOM   8621  O OG    . SER C 1 62  ? -36.458 -12.440 -43.536  1.00 47.04  ? 62  SER C OG    1 
ATOM   8622  N N     . THR C 1 63  ? -34.143 -10.222 -44.590  1.00 48.94  ? 63  THR C N     1 
ATOM   8623  C CA    . THR C 1 63  ? -32.737 -10.201 -44.230  1.00 49.15  ? 63  THR C CA    1 
ATOM   8624  C C     . THR C 1 63  ? -32.378 -11.478 -43.471  1.00 51.06  ? 63  THR C C     1 
ATOM   8625  O O     . THR C 1 63  ? -31.356 -12.090 -43.761  1.00 52.71  ? 63  THR C O     1 
ATOM   8626  C CB    . THR C 1 63  ? -32.424 -8.956  -43.383  1.00 45.54  ? 63  THR C CB    1 
ATOM   8627  O OG1   . THR C 1 63  ? -32.673 -7.813  -44.187  1.00 45.40  ? 63  THR C OG1   1 
ATOM   8628  C CG2   . THR C 1 63  ? -30.994 -8.894  -42.898  1.00 47.15  ? 63  THR C CG2   1 
ATOM   8629  N N     . GLU C 1 64  ? -33.209 -11.853 -42.485  1.00 50.03  ? 64  GLU C N     1 
ATOM   8630  C CA    . GLU C 1 64  ? -32.869 -12.913 -41.539  1.00 52.29  ? 64  GLU C CA    1 
ATOM   8631  C C     . GLU C 1 64  ? -32.932 -14.287 -42.218  1.00 50.57  ? 64  GLU C C     1 
ATOM   8632  O O     . GLU C 1 64  ? -32.093 -15.130 -41.955  1.00 43.79  ? 64  GLU C O     1 
ATOM   8633  C CB    . GLU C 1 64  ? -33.781 -12.846 -40.308  1.00 52.10  ? 64  GLU C CB    1 
ATOM   8634  C CG    . GLU C 1 64  ? -33.196 -13.486 -39.063  1.00 50.26  ? 64  GLU C CG    1 
ATOM   8635  C CD    . GLU C 1 64  ? -33.072 -15.002 -39.121  1.00 52.25  ? 64  GLU C CD    1 
ATOM   8636  O OE1   . GLU C 1 64  ? -33.937 -15.633 -39.752  1.00 48.96  ? 64  GLU C OE1   1 
ATOM   8637  O OE2   . GLU C 1 64  ? -32.123 -15.551 -38.513  1.00 54.62  ? 64  GLU C OE2   1 
ATOM   8638  N N     . GLU C 1 65  ? -33.883 -14.510 -43.132  1.00 53.73  ? 65  GLU C N     1 
ATOM   8639  C CA    . GLU C 1 65  ? -33.793 -15.658 -44.035  1.00 54.56  ? 65  GLU C CA    1 
ATOM   8640  C C     . GLU C 1 65  ? -32.444 -15.701 -44.770  1.00 54.87  ? 65  GLU C C     1 
ATOM   8641  O O     . GLU C 1 65  ? -31.807 -16.760 -44.812  1.00 48.53  ? 65  GLU C O     1 
ATOM   8642  C CB    . GLU C 1 65  ? -34.965 -15.667 -45.020  1.00 53.33  ? 65  GLU C CB    1 
ATOM   8643  C CG    . GLU C 1 65  ? -36.205 -16.304 -44.402  1.00 58.28  ? 65  GLU C CG    1 
ATOM   8644  C CD    . GLU C 1 65  ? -37.535 -16.012 -45.076  1.00 56.84  ? 65  GLU C CD    1 
ATOM   8645  O OE1   . GLU C 1 65  ? -37.582 -16.018 -46.317  1.00 57.93  ? 65  GLU C OE1   1 
ATOM   8646  O OE2   . GLU C 1 65  ? -38.527 -15.816 -44.350  1.00 58.54  ? 65  GLU C OE2   1 
ATOM   8647  N N     . VAL C 1 66  ? -32.020 -14.560 -45.353  1.00 47.19  ? 66  VAL C N     1 
ATOM   8648  C CA    . VAL C 1 66  ? -30.782 -14.466 -46.109  1.00 42.01  ? 66  VAL C CA    1 
ATOM   8649  C C     . VAL C 1 66  ? -29.609 -14.932 -45.248  1.00 42.59  ? 66  VAL C C     1 
ATOM   8650  O O     . VAL C 1 66  ? -28.757 -15.688 -45.699  1.00 48.70  ? 66  VAL C O     1 
ATOM   8651  C CB    . VAL C 1 66  ? -30.550 -13.037 -46.639  1.00 47.64  ? 66  VAL C CB    1 
ATOM   8652  C CG1   . VAL C 1 66  ? -29.140 -12.878 -47.182  1.00 50.30  ? 66  VAL C CG1   1 
ATOM   8653  C CG2   . VAL C 1 66  ? -31.572 -12.620 -47.696  1.00 46.12  ? 66  VAL C CG2   1 
ATOM   8654  N N     . GLN C 1 67  ? -29.580 -14.525 -43.984  1.00 46.42  ? 67  GLN C N     1 
ATOM   8655  C CA    . GLN C 1 67  ? -28.522 -14.950 -43.079  1.00 44.50  ? 67  GLN C CA    1 
ATOM   8656  C C     . GLN C 1 67  ? -28.544 -16.458 -42.861  1.00 42.44  ? 67  GLN C C     1 
ATOM   8657  O O     . GLN C 1 67  ? -27.479 -17.078 -42.795  1.00 41.01  ? 67  GLN C O     1 
ATOM   8658  C CB    . GLN C 1 67  ? -28.657 -14.300 -41.705  1.00 43.65  ? 67  GLN C CB    1 
ATOM   8659  C CG    . GLN C 1 67  ? -28.549 -12.783 -41.715  1.00 42.94  ? 67  GLN C CG    1 
ATOM   8660  C CD    . GLN C 1 67  ? -28.912 -12.249 -40.346  1.00 40.14  ? 67  GLN C CD    1 
ATOM   8661  O OE1   . GLN C 1 67  ? -29.985 -11.686 -40.130  1.00 41.02  ? 67  GLN C OE1   1 
ATOM   8662  N NE2   . GLN C 1 67  ? -28.006 -12.430 -39.402  1.00 36.66  ? 67  GLN C NE2   1 
ATOM   8663  N N     . GLU C 1 68  ? -29.745 -17.034 -42.691  1.00 48.33  ? 68  GLU C N     1 
ATOM   8664  C CA    . GLU C 1 68  ? -29.894 -18.474 -42.462  1.00 51.29  ? 68  GLU C CA    1 
ATOM   8665  C C     . GLU C 1 68  ? -29.376 -19.257 -43.668  1.00 45.80  ? 68  GLU C C     1 
ATOM   8666  O O     . GLU C 1 68  ? -28.549 -20.139 -43.488  1.00 39.34  ? 68  GLU C O     1 
ATOM   8667  C CB    . GLU C 1 68  ? -31.345 -18.855 -42.162  1.00 54.14  ? 68  GLU C CB    1 
ATOM   8668  C CG    . GLU C 1 68  ? -31.819 -18.402 -40.790  1.00 61.24  ? 68  GLU C CG    1 
ATOM   8669  C CD    . GLU C 1 68  ? -33.206 -18.892 -40.402  1.00 66.69  ? 68  GLU C CD    1 
ATOM   8670  O OE1   . GLU C 1 68  ? -34.146 -18.057 -40.314  1.00 66.22  ? 68  GLU C OE1   1 
ATOM   8671  O OE2   . GLU C 1 68  ? -33.345 -20.112 -40.177  1.00 73.00  ? 68  GLU C OE2   1 
ATOM   8672  N N     . ILE C 1 69  ? -29.798 -18.853 -44.881  1.00 43.48  ? 69  ILE C N     1 
ATOM   8673  C CA    . ILE C 1 69  ? -29.294 -19.409 -46.127  1.00 40.28  ? 69  ILE C CA    1 
ATOM   8674  C C     . ILE C 1 69  ? -27.776 -19.389 -46.147  1.00 44.81  ? 69  ILE C C     1 
ATOM   8675  O O     . ILE C 1 69  ? -27.142 -20.416 -46.353  1.00 50.87  ? 69  ILE C O     1 
ATOM   8676  C CB    . ILE C 1 69  ? -29.847 -18.642 -47.328  1.00 39.65  ? 69  ILE C CB    1 
ATOM   8677  C CG1   . ILE C 1 69  ? -31.344 -18.908 -47.492  1.00 44.03  ? 69  ILE C CG1   1 
ATOM   8678  C CG2   . ILE C 1 69  ? -29.087 -19.017 -48.573  1.00 44.11  ? 69  ILE C CG2   1 
ATOM   8679  C CD1   . ILE C 1 69  ? -32.073 -17.890 -48.306  1.00 43.95  ? 69  ILE C CD1   1 
ATOM   8680  N N     . VAL C 1 70  ? -27.202 -18.212 -45.924  1.00 43.47  ? 70  VAL C N     1 
ATOM   8681  C CA    . VAL C 1 70  ? -25.764 -18.067 -45.997  1.00 41.40  ? 70  VAL C CA    1 
ATOM   8682  C C     . VAL C 1 70  ? -25.079 -19.023 -45.034  1.00 40.73  ? 70  VAL C C     1 
ATOM   8683  O O     . VAL C 1 70  ? -23.972 -19.454 -45.327  1.00 42.67  ? 70  VAL C O     1 
ATOM   8684  C CB    . VAL C 1 70  ? -25.317 -16.613 -45.738  1.00 43.24  ? 70  VAL C CB    1 
ATOM   8685  C CG1   . VAL C 1 70  ? -23.804 -16.518 -45.575  1.00 45.76  ? 70  VAL C CG1   1 
ATOM   8686  C CG2   . VAL C 1 70  ? -25.764 -15.683 -46.856  1.00 44.21  ? 70  VAL C CG2   1 
ATOM   8687  N N     . ARG C 1 71  ? -25.690 -19.285 -43.871  1.00 46.04  ? 71  ARG C N     1 
ATOM   8688  C CA    . ARG C 1 71  ? -25.069 -20.129 -42.852  1.00 49.01  ? 71  ARG C CA    1 
ATOM   8689  C C     . ARG C 1 71  ? -25.038 -21.572 -43.337  1.00 51.03  ? 71  ARG C C     1 
ATOM   8690  O O     . ARG C 1 71  ? -24.020 -22.249 -43.175  1.00 56.53  ? 71  ARG C O     1 
ATOM   8691  C CB    . ARG C 1 71  ? -25.782 -20.047 -41.495  1.00 49.27  ? 71  ARG C CB    1 
ATOM   8692  C CG    . ARG C 1 71  ? -25.388 -18.834 -40.664  1.00 48.92  ? 71  ARG C CG    1 
ATOM   8693  C CD    . ARG C 1 71  ? -26.296 -18.560 -39.476  1.00 49.98  ? 71  ARG C CD    1 
ATOM   8694  N NE    . ARG C 1 71  ? -25.880 -17.337 -38.790  1.00 53.97  ? 71  ARG C NE    1 
ATOM   8695  C CZ    . ARG C 1 71  ? -26.693 -16.351 -38.411  1.00 49.29  ? 71  ARG C CZ    1 
ATOM   8696  N NH1   . ARG C 1 71  ? -27.993 -16.562 -38.356  1.00 50.90  ? 71  ARG C NH1   1 
ATOM   8697  N NH2   . ARG C 1 71  ? -26.203 -15.183 -38.013  1.00 45.92  ? 71  ARG C NH2   1 
ATOM   8698  N N     . VAL C 1 72  ? -26.147 -21.994 -43.952  1.00 47.88  ? 72  VAL C N     1 
ATOM   8699  C CA    . VAL C 1 72  ? -26.269 -23.294 -44.578  1.00 56.20  ? 72  VAL C CA    1 
ATOM   8700  C C     . VAL C 1 72  ? -25.267 -23.470 -45.724  1.00 59.78  ? 72  VAL C C     1 
ATOM   8701  O O     . VAL C 1 72  ? -24.675 -24.539 -45.843  1.00 56.45  ? 72  VAL C O     1 
ATOM   8702  C CB    . VAL C 1 72  ? -27.717 -23.521 -45.045  1.00 66.83  ? 72  VAL C CB    1 
ATOM   8703  C CG1   . VAL C 1 72  ? -27.830 -24.621 -46.097  1.00 70.58  ? 72  VAL C CG1   1 
ATOM   8704  C CG2   . VAL C 1 72  ? -28.608 -23.809 -43.849  1.00 64.04  ? 72  VAL C CG2   1 
ATOM   8705  N N     . ALA C 1 73  ? -25.060 -22.445 -46.563  1.00 57.88  ? 73  ALA C N     1 
ATOM   8706  C CA    . ALA C 1 73  ? -24.076 -22.537 -47.636  1.00 48.09  ? 73  ALA C CA    1 
ATOM   8707  C C     . ALA C 1 73  ? -22.671 -22.744 -47.087  1.00 47.75  ? 73  ALA C C     1 
ATOM   8708  O O     . ALA C 1 73  ? -21.898 -23.487 -47.670  1.00 53.49  ? 73  ALA C O     1 
ATOM   8709  C CB    . ALA C 1 73  ? -24.117 -21.349 -48.546  1.00 42.85  ? 73  ALA C CB    1 
ATOM   8710  N N     . ASN C 1 74  ? -22.335 -22.149 -45.947  1.00 56.54  ? 74  ASN C N     1 
ATOM   8711  C CA    . ASN C 1 74  ? -21.039 -22.431 -45.337  1.00 64.19  ? 74  ASN C CA    1 
ATOM   8712  C C     . ASN C 1 74  ? -20.995 -23.893 -44.881  1.00 65.98  ? 74  ASN C C     1 
ATOM   8713  O O     . ASN C 1 74  ? -19.944 -24.522 -44.895  1.00 60.25  ? 74  ASN C O     1 
ATOM   8714  C CB    . ASN C 1 74  ? -20.709 -21.486 -44.171  1.00 60.04  ? 74  ASN C CB    1 
ATOM   8715  C CG    . ASN C 1 74  ? -20.196 -20.138 -44.621  1.00 61.25  ? 74  ASN C CG    1 
ATOM   8716  O OD1   . ASN C 1 74  ? -19.007 -19.986 -44.889  1.00 61.37  ? 74  ASN C OD1   1 
ATOM   8717  N ND2   . ASN C 1 74  ? -21.088 -19.161 -44.711  1.00 60.02  ? 74  ASN C ND2   1 
ATOM   8718  N N     . GLU C 1 75  ? -22.149 -24.428 -44.472  1.00 69.82  ? 75  GLU C N     1 
ATOM   8719  C CA    . GLU C 1 75  ? -22.212 -25.709 -43.785  1.00 79.80  ? 75  GLU C CA    1 
ATOM   8720  C C     . GLU C 1 75  ? -21.924 -26.868 -44.759  1.00 71.59  ? 75  GLU C C     1 
ATOM   8721  O O     . GLU C 1 75  ? -21.526 -27.933 -44.312  1.00 74.88  ? 75  GLU C O     1 
ATOM   8722  C CB    . GLU C 1 75  ? -23.598 -25.794 -43.137  1.00 90.78  ? 75  GLU C CB    1 
ATOM   8723  C CG    . GLU C 1 75  ? -23.645 -26.332 -41.720  1.00 96.59  ? 75  GLU C CG    1 
ATOM   8724  C CD    . GLU C 1 75  ? -24.951 -25.960 -41.029  1.00 107.87 ? 75  GLU C CD    1 
ATOM   8725  O OE1   . GLU C 1 75  ? -25.978 -26.621 -41.302  1.00 107.66 ? 75  GLU C OE1   1 
ATOM   8726  O OE2   . GLU C 1 75  ? -24.958 -24.969 -40.260  1.00 106.19 ? 75  GLU C OE2   1 
ATOM   8727  N N     . PHE C 1 76  ? -22.094 -26.637 -46.075  1.00 61.98  ? 76  PHE C N     1 
ATOM   8728  C CA    . PHE C 1 76  ? -22.130 -27.646 -47.125  1.00 56.68  ? 76  PHE C CA    1 
ATOM   8729  C C     . PHE C 1 76  ? -21.323 -27.212 -48.350  1.00 55.84  ? 76  PHE C C     1 
ATOM   8730  O O     . PHE C 1 76  ? -21.524 -27.740 -49.443  1.00 57.68  ? 76  PHE C O     1 
ATOM   8731  C CB    . PHE C 1 76  ? -23.587 -27.846 -47.565  1.00 57.91  ? 76  PHE C CB    1 
ATOM   8732  C CG    . PHE C 1 76  ? -24.484 -28.463 -46.514  1.00 72.67  ? 76  PHE C CG    1 
ATOM   8733  C CD1   . PHE C 1 76  ? -24.319 -29.796 -46.127  1.00 70.91  ? 76  PHE C CD1   1 
ATOM   8734  C CD2   . PHE C 1 76  ? -25.486 -27.722 -45.902  1.00 67.42  ? 76  PHE C CD2   1 
ATOM   8735  C CE1   . PHE C 1 76  ? -25.141 -30.372 -45.169  1.00 65.23  ? 76  PHE C CE1   1 
ATOM   8736  C CE2   . PHE C 1 76  ? -26.294 -28.295 -44.931  1.00 68.66  ? 76  PHE C CE2   1 
ATOM   8737  C CZ    . PHE C 1 76  ? -26.118 -29.614 -44.564  1.00 72.70  ? 76  PHE C CZ    1 
ATOM   8738  N N     . GLY C 1 77  ? -20.469 -26.193 -48.177  1.00 58.91  ? 77  GLY C N     1 
ATOM   8739  C CA    . GLY C 1 77  ? -19.778 -25.498 -49.261  1.00 55.93  ? 77  GLY C CA    1 
ATOM   8740  C C     . GLY C 1 77  ? -20.588 -25.263 -50.549  1.00 55.48  ? 77  GLY C C     1 
ATOM   8741  O O     . GLY C 1 77  ? -20.039 -25.357 -51.633  1.00 57.48  ? 77  GLY C O     1 
ATOM   8742  N N     . VAL C 1 78  ? -21.860 -24.867 -50.472  1.00 55.10  ? 78  VAL C N     1 
ATOM   8743  C CA    . VAL C 1 78  ? -22.585 -24.508 -51.685  1.00 61.14  ? 78  VAL C CA    1 
ATOM   8744  C C     . VAL C 1 78  ? -22.467 -23.004 -51.989  1.00 62.93  ? 78  VAL C C     1 
ATOM   8745  O O     . VAL C 1 78  ? -22.907 -22.149 -51.220  1.00 57.74  ? 78  VAL C O     1 
ATOM   8746  C CB    . VAL C 1 78  ? -24.061 -24.942 -51.571  1.00 63.99  ? 78  VAL C CB    1 
ATOM   8747  C CG1   . VAL C 1 78  ? -24.900 -24.464 -52.761  1.00 61.44  ? 78  VAL C CG1   1 
ATOM   8748  C CG2   . VAL C 1 78  ? -24.166 -26.455 -51.405  1.00 66.42  ? 78  VAL C CG2   1 
ATOM   8749  N N     . PRO C 1 79  ? -21.953 -22.611 -53.173  1.00 60.84  ? 79  PRO C N     1 
ATOM   8750  C CA    . PRO C 1 79  ? -21.795 -21.197 -53.510  1.00 58.35  ? 79  PRO C CA    1 
ATOM   8751  C C     . PRO C 1 79  ? -23.082 -20.536 -53.985  1.00 55.64  ? 79  PRO C C     1 
ATOM   8752  O O     . PRO C 1 79  ? -23.948 -21.239 -54.488  1.00 50.40  ? 79  PRO C O     1 
ATOM   8753  C CB    . PRO C 1 79  ? -20.762 -21.229 -54.640  1.00 59.90  ? 79  PRO C CB    1 
ATOM   8754  C CG    . PRO C 1 79  ? -21.030 -22.535 -55.333  1.00 63.67  ? 79  PRO C CG    1 
ATOM   8755  C CD    . PRO C 1 79  ? -21.460 -23.496 -54.238  1.00 64.20  ? 79  PRO C CD    1 
ATOM   8756  N N     . LEU C 1 80  ? -23.138 -19.186 -53.858  1.00 57.51  ? 80  LEU C N     1 
ATOM   8757  C CA    . LEU C 1 80  ? -24.349 -18.382 -53.992  1.00 52.25  ? 80  LEU C CA    1 
ATOM   8758  C C     . LEU C 1 80  ? -24.099 -17.198 -54.910  1.00 52.84  ? 80  LEU C C     1 
ATOM   8759  O O     . LEU C 1 80  ? -23.076 -16.543 -54.763  1.00 56.66  ? 80  LEU C O     1 
ATOM   8760  C CB    . LEU C 1 80  ? -24.753 -17.839 -52.617  1.00 53.15  ? 80  LEU C CB    1 
ATOM   8761  C CG    . LEU C 1 80  ? -25.334 -18.860 -51.646  1.00 58.10  ? 80  LEU C CG    1 
ATOM   8762  C CD1   . LEU C 1 80  ? -25.540 -18.247 -50.269  1.00 58.83  ? 80  LEU C CD1   1 
ATOM   8763  C CD2   . LEU C 1 80  ? -26.647 -19.418 -52.182  1.00 60.09  ? 80  LEU C CD2   1 
ATOM   8764  N N     . TRP C 1 81  ? -25.081 -16.861 -55.762  1.00 48.77  ? 81  TRP C N     1 
ATOM   8765  C CA    . TRP C 1 81  ? -24.964 -15.700 -56.626  1.00 45.91  ? 81  TRP C CA    1 
ATOM   8766  C C     . TRP C 1 81  ? -26.098 -14.720 -56.344  1.00 47.92  ? 81  TRP C C     1 
ATOM   8767  O O     . TRP C 1 81  ? -27.231 -14.944 -56.732  1.00 48.52  ? 81  TRP C O     1 
ATOM   8768  C CB    . TRP C 1 81  ? -24.927 -16.095 -58.107  1.00 47.76  ? 81  TRP C CB    1 
ATOM   8769  C CG    . TRP C 1 81  ? -24.471 -14.964 -58.971  1.00 55.10  ? 81  TRP C CG    1 
ATOM   8770  C CD1   . TRP C 1 81  ? -25.233 -13.971 -59.516  1.00 60.76  ? 81  TRP C CD1   1 
ATOM   8771  C CD2   . TRP C 1 81  ? -23.113 -14.666 -59.337  1.00 52.58  ? 81  TRP C CD2   1 
ATOM   8772  N NE1   . TRP C 1 81  ? -24.443 -13.089 -60.210  1.00 62.28  ? 81  TRP C NE1   1 
ATOM   8773  C CE2   . TRP C 1 81  ? -23.142 -13.490 -60.113  1.00 50.97  ? 81  TRP C CE2   1 
ATOM   8774  C CE3   . TRP C 1 81  ? -21.892 -15.296 -59.101  1.00 52.57  ? 81  TRP C CE3   1 
ATOM   8775  C CZ2   . TRP C 1 81  ? -21.995 -12.918 -60.632  1.00 50.95  ? 81  TRP C CZ2   1 
ATOM   8776  C CZ3   . TRP C 1 81  ? -20.753 -14.723 -59.609  1.00 53.44  ? 81  TRP C CZ3   1 
ATOM   8777  C CH2   . TRP C 1 81  ? -20.810 -13.550 -60.353  1.00 47.95  ? 81  TRP C CH2   1 
ATOM   8778  N N     . PRO C 1 82  ? -25.846 -13.598 -55.638  1.00 53.96  ? 82  PRO C N     1 
ATOM   8779  C CA    . PRO C 1 82  ? -26.905 -12.672 -55.258  1.00 52.72  ? 82  PRO C CA    1 
ATOM   8780  C C     . PRO C 1 82  ? -27.326 -11.800 -56.416  1.00 60.77  ? 82  PRO C C     1 
ATOM   8781  O O     . PRO C 1 82  ? -26.473 -11.255 -57.120  1.00 68.35  ? 82  PRO C O     1 
ATOM   8782  C CB    . PRO C 1 82  ? -26.260 -11.755 -54.224  1.00 51.18  ? 82  PRO C CB    1 
ATOM   8783  C CG    . PRO C 1 82  ? -25.025 -12.499 -53.818  1.00 50.25  ? 82  PRO C CG    1 
ATOM   8784  C CD    . PRO C 1 82  ? -24.560 -13.198 -55.069  1.00 51.41  ? 82  PRO C CD    1 
ATOM   8785  N N     . VAL C 1 83  ? -28.641 -11.656 -56.550  1.00 62.40  ? 83  VAL C N     1 
ATOM   8786  C CA    . VAL C 1 83  ? -29.213 -10.739 -57.514  1.00 64.65  ? 83  VAL C CA    1 
ATOM   8787  C C     . VAL C 1 83  ? -30.383 -10.008 -56.852  1.00 65.76  ? 83  VAL C C     1 
ATOM   8788  O O     . VAL C 1 83  ? -31.169 -10.612 -56.125  1.00 71.26  ? 83  VAL C O     1 
ATOM   8789  C CB    . VAL C 1 83  ? -29.601 -11.513 -58.782  1.00 58.73  ? 83  VAL C CB    1 
ATOM   8790  C CG1   . VAL C 1 83  ? -28.403 -12.272 -59.329  1.00 60.15  ? 83  VAL C CG1   1 
ATOM   8791  C CG2   . VAL C 1 83  ? -30.735 -12.480 -58.530  1.00 59.11  ? 83  VAL C CG2   1 
ATOM   8792  N N     . SER C 1 84  ? -30.447 -8.687  -57.049  1.00 56.33  ? 84  SER C N     1 
ATOM   8793  C CA    . SER C 1 84  ? -31.502 -7.889  -56.452  1.00 62.75  ? 84  SER C CA    1 
ATOM   8794  C C     . SER C 1 84  ? -32.795 -8.182  -57.212  1.00 58.44  ? 84  SER C C     1 
ATOM   8795  O O     . SER C 1 84  ? -33.828 -8.490  -56.636  1.00 53.45  ? 84  SER C O     1 
ATOM   8796  C CB    . SER C 1 84  ? -31.155 -6.386  -56.444  1.00 62.58  ? 84  SER C CB    1 
ATOM   8797  O OG    . SER C 1 84  ? -30.095 -6.060  -55.547  1.00 52.64  ? 84  SER C OG    1 
ATOM   8798  N N     . ARG C 1 85  ? -32.703 -8.060  -58.534  1.00 68.19  ? 85  ARG C N     1 
ATOM   8799  C CA    . ARG C 1 85  ? -33.825 -8.258  -59.434  1.00 66.41  ? 85  ARG C CA    1 
ATOM   8800  C C     . ARG C 1 85  ? -33.372 -8.962  -60.702  1.00 66.06  ? 85  ARG C C     1 
ATOM   8801  O O     . ARG C 1 85  ? -34.218 -9.435  -61.452  1.00 61.10  ? 85  ARG C O     1 
ATOM   8802  C CB    . ARG C 1 85  ? -34.466 -6.929  -59.818  1.00 61.59  ? 85  ARG C CB    1 
ATOM   8803  C CG    . ARG C 1 85  ? -35.464 -6.430  -58.790  1.00 61.00  ? 85  ARG C CG    1 
ATOM   8804  C CD    . ARG C 1 85  ? -36.016 -5.104  -59.245  1.00 58.38  ? 85  ARG C CD    1 
ATOM   8805  N NE    . ARG C 1 85  ? -36.820 -5.238  -60.437  1.00 62.18  ? 85  ARG C NE    1 
ATOM   8806  C CZ    . ARG C 1 85  ? -38.072 -5.672  -60.470  1.00 58.69  ? 85  ARG C CZ    1 
ATOM   8807  N NH1   . ARG C 1 85  ? -38.732 -5.907  -59.358  1.00 59.40  ? 85  ARG C NH1   1 
ATOM   8808  N NH2   . ARG C 1 85  ? -38.673 -5.841  -61.631  1.00 61.45  ? 85  ARG C NH2   1 
ATOM   8809  N N     . GLY C 1 86  ? -32.055 -8.974  -60.940  1.00 72.66  ? 86  GLY C N     1 
ATOM   8810  C CA    . GLY C 1 86  ? -31.455 -9.849  -61.932  1.00 82.30  ? 86  GLY C CA    1 
ATOM   8811  C C     . GLY C 1 86  ? -31.724 -9.380  -63.361  1.00 84.91  ? 86  GLY C C     1 
ATOM   8812  O O     . GLY C 1 86  ? -31.626 -10.168 -64.306  1.00 88.01  ? 86  GLY C O     1 
ATOM   8813  N N     . LYS C 1 87  ? -32.042 -8.086  -63.500  1.00 89.54  ? 87  LYS C N     1 
ATOM   8814  C CA    . LYS C 1 87  ? -32.443 -7.515  -64.773  1.00 91.62  ? 87  LYS C CA    1 
ATOM   8815  C C     . LYS C 1 87  ? -31.272 -6.730  -65.363  1.00 81.57  ? 87  LYS C C     1 
ATOM   8816  O O     . LYS C 1 87  ? -31.488 -5.663  -65.941  1.00 82.07  ? 87  LYS C O     1 
ATOM   8817  C CB    . LYS C 1 87  ? -33.690 -6.650  -64.556  1.00 94.34  ? 87  LYS C CB    1 
ATOM   8818  C CG    . LYS C 1 87  ? -34.936 -7.410  -64.110  1.00 95.22  ? 87  LYS C CG    1 
ATOM   8819  C CD    . LYS C 1 87  ? -35.627 -8.135  -65.248  1.00 107.40 ? 87  LYS C CD    1 
ATOM   8820  C CE    . LYS C 1 87  ? -37.030 -8.604  -64.922  1.00 98.46  ? 87  LYS C CE    1 
ATOM   8821  N NZ    . LYS C 1 87  ? -36.998 -9.750  -63.988  1.00 87.18  ? 87  LYS C NZ    1 
ATOM   8822  N N     . ASN C 1 88  ? -30.060 -7.312  -65.258  1.00 80.52  ? 88  ASN C N     1 
ATOM   8823  C CA    . ASN C 1 88  ? -28.799 -6.672  -65.632  1.00 87.09  ? 88  ASN C CA    1 
ATOM   8824  C C     . ASN C 1 88  ? -28.394 -7.097  -67.049  1.00 89.92  ? 88  ASN C C     1 
ATOM   8825  O O     . ASN C 1 88  ? -27.347 -7.714  -67.245  1.00 82.08  ? 88  ASN C O     1 
ATOM   8826  C CB    . ASN C 1 88  ? -27.691 -6.984  -64.612  1.00 79.44  ? 88  ASN C CB    1 
ATOM   8827  C CG    . ASN C 1 88  ? -26.520 -6.012  -64.604  1.00 78.27  ? 88  ASN C CG    1 
ATOM   8828  O OD1   . ASN C 1 88  ? -26.586 -4.896  -65.129  1.00 79.15  ? 88  ASN C OD1   1 
ATOM   8829  N ND2   . ASN C 1 88  ? -25.438 -6.420  -63.963  1.00 70.58  ? 88  ASN C ND2   1 
ATOM   8830  N N     . PHE C 1 89  ? -29.229 -6.724  -68.032  1.00 92.86  ? 89  PHE C N     1 
ATOM   8831  C CA    . PHE C 1 89  ? -29.044 -7.086  -69.429  1.00 87.14  ? 89  PHE C CA    1 
ATOM   8832  C C     . PHE C 1 89  ? -27.760 -6.429  -69.945  1.00 83.66  ? 89  PHE C C     1 
ATOM   8833  O O     . PHE C 1 89  ? -27.451 -5.297  -69.557  1.00 69.63  ? 89  PHE C O     1 
ATOM   8834  C CB    . PHE C 1 89  ? -30.295 -6.694  -70.229  1.00 98.31  ? 89  PHE C CB    1 
ATOM   8835  C CG    . PHE C 1 89  ? -31.606 -7.233  -69.697  1.00 101.88 ? 89  PHE C CG    1 
ATOM   8836  C CD1   . PHE C 1 89  ? -31.798 -8.598  -69.511  1.00 104.73 ? 89  PHE C CD1   1 
ATOM   8837  C CD2   . PHE C 1 89  ? -32.654 -6.378  -69.380  1.00 104.95 ? 89  PHE C CD2   1 
ATOM   8838  C CE1   . PHE C 1 89  ? -32.996 -9.095  -69.012  1.00 103.05 ? 89  PHE C CE1   1 
ATOM   8839  C CE2   . PHE C 1 89  ? -33.855 -6.878  -68.889  1.00 109.91 ? 89  PHE C CE2   1 
ATOM   8840  C CZ    . PHE C 1 89  ? -34.027 -8.235  -68.710  1.00 101.28 ? 89  PHE C CZ    1 
ATOM   8841  N N     . ALA C 1 90  ? -27.007 -7.186  -70.771  1.00 83.73  ? 90  ALA C N     1 
ATOM   8842  C CA    . ALA C 1 90  ? -25.753 -6.778  -71.412  1.00 85.45  ? 90  ALA C CA    1 
ATOM   8843  C C     . ALA C 1 90  ? -24.529 -7.021  -70.519  1.00 92.46  ? 90  ALA C C     1 
ATOM   8844  O O     . ALA C 1 90  ? -23.389 -6.800  -70.960  1.00 75.97  ? 90  ALA C O     1 
ATOM   8845  C CB    . ALA C 1 90  ? -25.801 -5.339  -71.865  1.00 82.19  ? 90  ALA C CB    1 
ATOM   8846  N N     . TYR C 1 91  ? -24.781 -7.453  -69.270  1.00 91.23  ? 91  TYR C N     1 
ATOM   8847  C CA    . TYR C 1 91  ? -23.740 -7.742  -68.292  1.00 84.24  ? 91  TYR C CA    1 
ATOM   8848  C C     . TYR C 1 91  ? -23.912 -9.169  -67.755  1.00 76.90  ? 91  TYR C C     1 
ATOM   8849  O O     . TYR C 1 91  ? -23.069 -9.641  -66.996  1.00 69.22  ? 91  TYR C O     1 
ATOM   8850  C CB    . TYR C 1 91  ? -23.723 -6.659  -67.200  1.00 85.25  ? 91  TYR C CB    1 
ATOM   8851  C CG    . TYR C 1 91  ? -23.484 -5.264  -67.725  1.00 81.66  ? 91  TYR C CG    1 
ATOM   8852  C CD1   . TYR C 1 91  ? -22.203 -4.803  -67.990  1.00 81.51  ? 91  TYR C CD1   1 
ATOM   8853  C CD2   . TYR C 1 91  ? -24.545 -4.429  -68.038  1.00 79.97  ? 91  TYR C CD2   1 
ATOM   8854  C CE1   . TYR C 1 91  ? -21.982 -3.540  -68.519  1.00 76.97  ? 91  TYR C CE1   1 
ATOM   8855  C CE2   . TYR C 1 91  ? -24.341 -3.166  -68.570  1.00 78.84  ? 91  TYR C CE2   1 
ATOM   8856  C CZ    . TYR C 1 91  ? -23.055 -2.719  -68.816  1.00 80.22  ? 91  TYR C CZ    1 
ATOM   8857  O OH    . TYR C 1 91  ? -22.864 -1.465  -69.358  1.00 92.27  ? 91  TYR C OH    1 
ATOM   8858  N N     . GLY C 1 92  ? -24.961 -9.878  -68.202  1.00 73.31  ? 92  GLY C N     1 
ATOM   8859  C CA    . GLY C 1 92  ? -25.104 -11.300 -67.926  1.00 78.23  ? 92  GLY C CA    1 
ATOM   8860  C C     . GLY C 1 92  ? -26.527 -11.708 -67.536  1.00 79.67  ? 92  GLY C C     1 
ATOM   8861  O O     . GLY C 1 92  ? -26.831 -12.905 -67.398  1.00 69.98  ? 92  GLY C O     1 
ATOM   8862  N N     . GLY C 1 93  ? -27.392 -10.705 -67.356  1.00 71.16  ? 93  GLY C N     1 
ATOM   8863  C CA    . GLY C 1 93  ? -28.675 -10.936 -66.721  1.00 84.89  ? 93  GLY C CA    1 
ATOM   8864  C C     . GLY C 1 93  ? -28.497 -11.408 -65.278  1.00 78.41  ? 93  GLY C C     1 
ATOM   8865  O O     . GLY C 1 93  ? -27.818 -10.742 -64.500  1.00 70.13  ? 93  GLY C O     1 
ATOM   8866  N N     . ALA C 1 94  ? -29.074 -12.578 -64.966  1.00 82.97  ? 94  ALA C N     1 
ATOM   8867  C CA    . ALA C 1 94  ? -29.127 -13.101 -63.606  1.00 83.45  ? 94  ALA C CA    1 
ATOM   8868  C C     . ALA C 1 94  ? -28.172 -14.279 -63.420  1.00 77.40  ? 94  ALA C C     1 
ATOM   8869  O O     . ALA C 1 94  ? -28.262 -14.948 -62.396  1.00 78.72  ? 94  ALA C O     1 
ATOM   8870  C CB    . ALA C 1 94  ? -30.542 -13.529 -63.271  1.00 82.47  ? 94  ALA C CB    1 
ATOM   8871  N N     . ALA C 1 95  ? -27.255 -14.512 -64.377  1.00 77.13  ? 95  ALA C N     1 
ATOM   8872  C CA    . ALA C 1 95  ? -26.478 -15.750 -64.428  1.00 80.31  ? 95  ALA C CA    1 
ATOM   8873  C C     . ALA C 1 95  ? -25.145 -15.658 -63.665  1.00 72.78  ? 95  ALA C C     1 
ATOM   8874  O O     . ALA C 1 95  ? -24.468 -14.631 -63.649  1.00 79.85  ? 95  ALA C O     1 
ATOM   8875  C CB    . ALA C 1 95  ? -26.251 -16.127 -65.876  1.00 82.41  ? 95  ALA C CB    1 
ATOM   8876  N N     . PRO C 1 96  ? -24.669 -16.766 -63.066  1.00 65.76  ? 96  PRO C N     1 
ATOM   8877  C CA    . PRO C 1 96  ? -23.367 -16.804 -62.395  1.00 71.88  ? 96  PRO C CA    1 
ATOM   8878  C C     . PRO C 1 96  ? -22.138 -17.184 -63.236  1.00 76.51  ? 96  PRO C C     1 
ATOM   8879  O O     . PRO C 1 96  ? -22.111 -18.238 -63.868  1.00 83.36  ? 96  PRO C O     1 
ATOM   8880  C CB    . PRO C 1 96  ? -23.622 -17.917 -61.367  1.00 68.61  ? 96  PRO C CB    1 
ATOM   8881  C CG    . PRO C 1 96  ? -24.457 -18.924 -62.133  1.00 68.56  ? 96  PRO C CG    1 
ATOM   8882  C CD    . PRO C 1 96  ? -25.352 -18.063 -63.007  1.00 70.95  ? 96  PRO C CD    1 
ATOM   8883  N N     . VAL C 1 97  ? -21.102 -16.327 -63.179  1.00 69.91  ? 97  VAL C N     1 
ATOM   8884  C CA    . VAL C 1 97  ? -19.759 -16.589 -63.687  1.00 63.53  ? 97  VAL C CA    1 
ATOM   8885  C C     . VAL C 1 97  ? -19.467 -18.085 -63.662  1.00 66.69  ? 97  VAL C C     1 
ATOM   8886  O O     . VAL C 1 97  ? -19.243 -18.694 -64.711  1.00 60.23  ? 97  VAL C O     1 
ATOM   8887  C CB    . VAL C 1 97  ? -18.701 -15.804 -62.888  1.00 63.63  ? 97  VAL C CB    1 
ATOM   8888  C CG1   . VAL C 1 97  ? -17.303 -16.341 -63.104  1.00 66.05  ? 97  VAL C CG1   1 
ATOM   8889  C CG2   . VAL C 1 97  ? -18.744 -14.310 -63.209  1.00 74.48  ? 97  VAL C CG2   1 
ATOM   8890  N N     . MET C 1 98  ? -19.496 -18.668 -62.459  1.00 65.55  ? 98  MET C N     1 
ATOM   8891  C CA    . MET C 1 98  ? -19.230 -20.086 -62.337  1.00 75.31  ? 98  MET C CA    1 
ATOM   8892  C C     . MET C 1 98  ? -20.566 -20.810 -62.439  1.00 88.95  ? 98  MET C C     1 
ATOM   8893  O O     . MET C 1 98  ? -21.585 -20.307 -61.972  1.00 97.56  ? 98  MET C O     1 
ATOM   8894  C CB    . MET C 1 98  ? -18.526 -20.420 -61.018  1.00 71.82  ? 98  MET C CB    1 
ATOM   8895  C CG    . MET C 1 98  ? -17.870 -21.799 -61.017  1.00 67.95  ? 98  MET C CG    1 
ATOM   8896  S SD    . MET C 1 98  ? -17.048 -22.228 -59.441  1.00 78.75  ? 98  MET C SD    1 
ATOM   8897  C CE    . MET C 1 98  ? -18.473 -22.369 -58.356  1.00 61.40  ? 98  MET C CE    1 
ATOM   8898  N N     . SER C 1 99  ? -20.551 -21.976 -63.087  1.00 92.91  ? 99  SER C N     1 
ATOM   8899  C CA    . SER C 1 99  ? -21.728 -22.820 -63.165  1.00 85.18  ? 99  SER C CA    1 
ATOM   8900  C C     . SER C 1 99  ? -21.863 -23.630 -61.882  1.00 80.74  ? 99  SER C C     1 
ATOM   8901  O O     . SER C 1 99  ? -20.869 -23.924 -61.203  1.00 67.16  ? 99  SER C O     1 
ATOM   8902  C CB    . SER C 1 99  ? -21.663 -23.730 -64.364  1.00 90.63  ? 99  SER C CB    1 
ATOM   8903  O OG    . SER C 1 99  ? -21.738 -22.986 -65.567  1.00 93.41  ? 99  SER C OG    1 
ATOM   8904  N N     . GLY C 1 100 ? -23.113 -24.025 -61.604  1.00 80.90  ? 100 GLY C N     1 
ATOM   8905  C CA    . GLY C 1 100 ? -23.448 -24.811 -60.427  1.00 77.26  ? 100 GLY C CA    1 
ATOM   8906  C C     . GLY C 1 100 ? -23.675 -23.928 -59.204  1.00 77.28  ? 100 GLY C C     1 
ATOM   8907  O O     . GLY C 1 100 ? -23.821 -24.435 -58.092  1.00 83.00  ? 100 GLY C O     1 
ATOM   8908  N N     . THR C 1 101 ? -23.678 -22.607 -59.435  1.00 76.57  ? 101 THR C N     1 
ATOM   8909  C CA    . THR C 1 101 ? -23.916 -21.624 -58.398  1.00 69.59  ? 101 THR C CA    1 
ATOM   8910  C C     . THR C 1 101 ? -25.420 -21.535 -58.200  1.00 73.23  ? 101 THR C C     1 
ATOM   8911  O O     . THR C 1 101 ? -26.145 -21.494 -59.193  1.00 80.22  ? 101 THR C O     1 
ATOM   8912  C CB    . THR C 1 101 ? -23.338 -20.261 -58.797  1.00 64.26  ? 101 THR C CB    1 
ATOM   8913  O OG1   . THR C 1 101 ? -21.998 -20.466 -59.234  1.00 58.92  ? 101 THR C OG1   1 
ATOM   8914  C CG2   . THR C 1 101 ? -23.331 -19.269 -57.658  1.00 68.78  ? 101 THR C CG2   1 
ATOM   8915  N N     . VAL C 1 102 ? -25.866 -21.539 -56.935  1.00 62.19  ? 102 VAL C N     1 
ATOM   8916  C CA    . VAL C 1 102 ? -27.260 -21.310 -56.600  1.00 52.41  ? 102 VAL C CA    1 
ATOM   8917  C C     . VAL C 1 102 ? -27.489 -19.800 -56.613  1.00 54.39  ? 102 VAL C C     1 
ATOM   8918  O O     . VAL C 1 102 ? -26.738 -19.052 -55.993  1.00 55.64  ? 102 VAL C O     1 
ATOM   8919  C CB    . VAL C 1 102 ? -27.603 -21.919 -55.233  1.00 57.86  ? 102 VAL C CB    1 
ATOM   8920  C CG1   . VAL C 1 102 ? -29.042 -21.657 -54.826  1.00 63.44  ? 102 VAL C CG1   1 
ATOM   8921  C CG2   . VAL C 1 102 ? -27.315 -23.404 -55.185  1.00 63.20  ? 102 VAL C CG2   1 
ATOM   8922  N N     . VAL C 1 103 ? -28.500 -19.348 -57.363  1.00 53.49  ? 103 VAL C N     1 
ATOM   8923  C CA    . VAL C 1 103 ? -28.851 -17.940 -57.387  1.00 57.46  ? 103 VAL C CA    1 
ATOM   8924  C C     . VAL C 1 103 ? -29.567 -17.585 -56.089  1.00 62.21  ? 103 VAL C C     1 
ATOM   8925  O O     . VAL C 1 103 ? -30.488 -18.300 -55.680  1.00 60.38  ? 103 VAL C O     1 
ATOM   8926  C CB    . VAL C 1 103 ? -29.715 -17.581 -58.607  1.00 58.29  ? 103 VAL C CB    1 
ATOM   8927  C CG1   . VAL C 1 103 ? -30.404 -16.237 -58.435  1.00 61.36  ? 103 VAL C CG1   1 
ATOM   8928  C CG2   . VAL C 1 103 ? -28.905 -17.596 -59.891  1.00 61.51  ? 103 VAL C CG2   1 
ATOM   8929  N N     . LEU C 1 104 ? -29.132 -16.479 -55.455  1.00 59.49  ? 104 LEU C N     1 
ATOM   8930  C CA    . LEU C 1 104 ? -29.879 -15.890 -54.361  1.00 50.56  ? 104 LEU C CA    1 
ATOM   8931  C C     . LEU C 1 104 ? -30.665 -14.719 -54.925  1.00 54.09  ? 104 LEU C C     1 
ATOM   8932  O O     . LEU C 1 104 ? -30.111 -13.661 -55.205  1.00 55.38  ? 104 LEU C O     1 
ATOM   8933  C CB    . LEU C 1 104 ? -28.960 -15.467 -53.216  1.00 51.87  ? 104 LEU C CB    1 
ATOM   8934  C CG    . LEU C 1 104 ? -29.692 -14.939 -51.976  1.00 54.30  ? 104 LEU C CG    1 
ATOM   8935  C CD1   . LEU C 1 104 ? -30.220 -16.070 -51.127  1.00 56.03  ? 104 LEU C CD1   1 
ATOM   8936  C CD2   . LEU C 1 104 ? -28.793 -14.070 -51.122  1.00 57.28  ? 104 LEU C CD2   1 
ATOM   8937  N N     . ASP C 1 105 ? -31.970 -14.944 -55.103  1.00 56.06  ? 105 ASP C N     1 
ATOM   8938  C CA    . ASP C 1 105 ? -32.817 -13.984 -55.780  1.00 54.63  ? 105 ASP C CA    1 
ATOM   8939  C C     . ASP C 1 105 ? -33.562 -13.199 -54.717  1.00 56.94  ? 105 ASP C C     1 
ATOM   8940  O O     . ASP C 1 105 ? -34.263 -13.789 -53.901  1.00 59.29  ? 105 ASP C O     1 
ATOM   8941  C CB    . ASP C 1 105 ? -33.770 -14.696 -56.735  1.00 50.79  ? 105 ASP C CB    1 
ATOM   8942  C CG    . ASP C 1 105 ? -34.669 -13.748 -57.496  1.00 56.08  ? 105 ASP C CG    1 
ATOM   8943  O OD1   . ASP C 1 105 ? -34.592 -12.527 -57.226  1.00 60.49  ? 105 ASP C OD1   1 
ATOM   8944  O OD2   . ASP C 1 105 ? -35.432 -14.239 -58.369  1.00 65.66  ? 105 ASP C OD2   1 
ATOM   8945  N N     . MET C 1 106 ? -33.410 -11.874 -54.717  1.00 57.23  ? 106 MET C N     1 
ATOM   8946  C CA    . MET C 1 106 ? -33.955 -11.091 -53.615  1.00 60.82  ? 106 MET C CA    1 
ATOM   8947  C C     . MET C 1 106 ? -35.086 -10.208 -54.111  1.00 56.37  ? 106 MET C C     1 
ATOM   8948  O O     . MET C 1 106 ? -35.385 -9.198  -53.486  1.00 62.52  ? 106 MET C O     1 
ATOM   8949  C CB    . MET C 1 106 ? -32.859 -10.279 -52.919  1.00 60.87  ? 106 MET C CB    1 
ATOM   8950  C CG    . MET C 1 106 ? -32.238 -11.068 -51.770  1.00 62.68  ? 106 MET C CG    1 
ATOM   8951  S SD    . MET C 1 106 ? -30.639 -10.466 -51.230  1.00 63.66  ? 106 MET C SD    1 
ATOM   8952  C CE    . MET C 1 106 ? -29.841 -10.279 -52.823  1.00 73.81  ? 106 MET C CE    1 
ATOM   8953  N N     . ASN C 1 107 ? -35.743 -10.672 -55.182  1.00 58.18  ? 107 ASN C N     1 
ATOM   8954  C CA    . ASN C 1 107 ? -36.930 -10.050 -55.747  1.00 64.43  ? 107 ASN C CA    1 
ATOM   8955  C C     . ASN C 1 107 ? -38.021 -9.755  -54.723  1.00 50.66  ? 107 ASN C C     1 
ATOM   8956  O O     . ASN C 1 107 ? -38.700 -8.755  -54.852  1.00 44.91  ? 107 ASN C O     1 
ATOM   8957  C CB    . ASN C 1 107 ? -37.579 -10.941 -56.806  1.00 75.00  ? 107 ASN C CB    1 
ATOM   8958  C CG    . ASN C 1 107 ? -37.224 -10.453 -58.186  1.00 92.81  ? 107 ASN C CG    1 
ATOM   8959  O OD1   . ASN C 1 107 ? -36.510 -11.129 -58.923  1.00 113.08 ? 107 ASN C OD1   1 
ATOM   8960  N ND2   . ASN C 1 107 ? -37.683 -9.255  -58.512  1.00 95.83  ? 107 ASN C ND2   1 
ATOM   8961  N N     . ARG C 1 108 ? -38.226 -10.660 -53.769  1.00 51.49  ? 108 ARG C N     1 
ATOM   8962  C CA    . ARG C 1 108 ? -39.394 -10.611 -52.902  1.00 59.25  ? 108 ARG C CA    1 
ATOM   8963  C C     . ARG C 1 108 ? -39.179 -9.564  -51.820  1.00 56.22  ? 108 ARG C C     1 
ATOM   8964  O O     . ARG C 1 108 ? -40.132 -9.070  -51.233  1.00 48.11  ? 108 ARG C O     1 
ATOM   8965  C CB    . ARG C 1 108 ? -39.658 -11.975 -52.256  1.00 54.12  ? 108 ARG C CB    1 
ATOM   8966  C CG    . ARG C 1 108 ? -40.132 -13.025 -53.249  1.00 54.88  ? 108 ARG C CG    1 
ATOM   8967  C CD    . ARG C 1 108 ? -40.181 -14.402 -52.624  1.00 57.18  ? 108 ARG C CD    1 
ATOM   8968  N NE    . ARG C 1 108 ? -41.185 -14.457 -51.575  1.00 55.87  ? 108 ARG C NE    1 
ATOM   8969  C CZ    . ARG C 1 108 ? -41.085 -15.152 -50.451  1.00 53.31  ? 108 ARG C CZ    1 
ATOM   8970  N NH1   . ARG C 1 108 ? -39.988 -15.842 -50.154  1.00 45.07  ? 108 ARG C NH1   1 
ATOM   8971  N NH2   . ARG C 1 108 ? -42.133 -15.178 -49.649  1.00 50.45  ? 108 ARG C NH2   1 
ATOM   8972  N N     . MET C 1 109 ? -37.907 -9.294  -51.530  1.00 56.38  ? 109 MET C N     1 
ATOM   8973  C CA    . MET C 1 109 ? -37.542 -8.279  -50.567  1.00 52.92  ? 109 MET C CA    1 
ATOM   8974  C C     . MET C 1 109 ? -37.618 -6.939  -51.289  1.00 49.95  ? 109 MET C C     1 
ATOM   8975  O O     . MET C 1 109 ? -36.590 -6.420  -51.738  1.00 50.34  ? 109 MET C O     1 
ATOM   8976  C CB    . MET C 1 109 ? -36.132 -8.551  -50.033  1.00 51.34  ? 109 MET C CB    1 
ATOM   8977  C CG    . MET C 1 109 ? -36.088 -9.737  -49.093  1.00 52.99  ? 109 MET C CG    1 
ATOM   8978  S SD    . MET C 1 109 ? -34.397 -10.304 -48.767  1.00 57.20  ? 109 MET C SD    1 
ATOM   8979  C CE    . MET C 1 109 ? -33.747 -8.856  -47.936  1.00 55.70  ? 109 MET C CE    1 
ATOM   8980  N N     . ASN C 1 110 ? -38.852 -6.417  -51.407  1.00 42.91  ? 110 ASN C N     1 
ATOM   8981  C CA    . ASN C 1 110 ? -39.145 -5.292  -52.277  1.00 46.26  ? 110 ASN C CA    1 
ATOM   8982  C C     . ASN C 1 110 ? -39.840 -4.130  -51.545  1.00 40.74  ? 110 ASN C C     1 
ATOM   8983  O O     . ASN C 1 110 ? -40.533 -3.336  -52.171  1.00 40.78  ? 110 ASN C O     1 
ATOM   8984  C CB    . ASN C 1 110 ? -39.984 -5.811  -53.442  1.00 48.36  ? 110 ASN C CB    1 
ATOM   8985  C CG    . ASN C 1 110 ? -41.361 -6.210  -52.969  1.00 48.55  ? 110 ASN C CG    1 
ATOM   8986  O OD1   . ASN C 1 110 ? -41.530 -6.641  -51.841  1.00 54.98  ? 110 ASN C OD1   1 
ATOM   8987  N ND2   . ASN C 1 110 ? -42.370 -5.934  -53.756  1.00 49.53  ? 110 ASN C ND2   1 
ATOM   8988  N N     . ARG C 1 111 ? -39.665 -3.997  -50.232  1.00 43.38  ? 111 ARG C N     1 
ATOM   8989  C CA    . ARG C 1 111 ? -40.326 -2.933  -49.501  1.00 45.16  ? 111 ARG C CA    1 
ATOM   8990  C C     . ARG C 1 111 ? -39.573 -1.623  -49.725  1.00 46.44  ? 111 ARG C C     1 
ATOM   8991  O O     . ARG C 1 111 ? -38.349 -1.609  -49.744  1.00 46.94  ? 111 ARG C O     1 
ATOM   8992  C CB    . ARG C 1 111 ? -40.357 -3.260  -48.007  1.00 53.17  ? 111 ARG C CB    1 
ATOM   8993  C CG    . ARG C 1 111 ? -41.156 -4.500  -47.628  1.00 59.25  ? 111 ARG C CG    1 
ATOM   8994  C CD    . ARG C 1 111 ? -41.093 -4.867  -46.144  1.00 68.72  ? 111 ARG C CD    1 
ATOM   8995  N NE    . ARG C 1 111 ? -39.953 -5.708  -45.752  1.00 88.67  ? 111 ARG C NE    1 
ATOM   8996  C CZ    . ARG C 1 111 ? -39.693 -6.947  -46.208  1.00 99.64  ? 111 ARG C CZ    1 
ATOM   8997  N NH1   . ARG C 1 111 ? -40.452 -7.493  -47.147  1.00 94.86  ? 111 ARG C NH1   1 
ATOM   8998  N NH2   . ARG C 1 111 ? -38.657 -7.637  -45.740  1.00 85.42  ? 111 ARG C NH2   1 
ATOM   8999  N N     . ILE C 1 112 ? -40.307 -0.524  -49.915  1.00 45.33  ? 112 ILE C N     1 
ATOM   9000  C CA    . ILE C 1 112 ? -39.769 0.823   -49.730  1.00 47.10  ? 112 ILE C CA    1 
ATOM   9001  C C     . ILE C 1 112 ? -39.892 1.236   -48.256  1.00 41.67  ? 112 ILE C C     1 
ATOM   9002  O O     . ILE C 1 112 ? -40.969 1.575   -47.813  1.00 41.02  ? 112 ILE C O     1 
ATOM   9003  C CB    . ILE C 1 112 ? -40.509 1.803   -50.661  1.00 45.25  ? 112 ILE C CB    1 
ATOM   9004  C CG1   . ILE C 1 112 ? -40.304 1.431   -52.134  1.00 43.50  ? 112 ILE C CG1   1 
ATOM   9005  C CG2   . ILE C 1 112 ? -40.087 3.235   -50.369  1.00 44.64  ? 112 ILE C CG2   1 
ATOM   9006  C CD1   . ILE C 1 112 ? -41.222 2.167   -53.096  1.00 42.50  ? 112 ILE C CD1   1 
ATOM   9007  N N     . LEU C 1 113 ? -38.807 1.183   -47.473  1.00 43.77  ? 113 LEU C N     1 
ATOM   9008  C CA    . LEU C 1 113 ? -38.896 1.345   -46.021  1.00 44.54  ? 113 LEU C CA    1 
ATOM   9009  C C     . LEU C 1 113 ? -39.075 2.810   -45.610  1.00 46.30  ? 113 LEU C C     1 
ATOM   9010  O O     . LEU C 1 113 ? -39.702 3.088   -44.602  1.00 53.14  ? 113 LEU C O     1 
ATOM   9011  C CB    . LEU C 1 113 ? -37.650 0.725   -45.378  1.00 44.42  ? 113 LEU C CB    1 
ATOM   9012  C CG    . LEU C 1 113 ? -37.563 -0.799  -45.491  1.00 46.00  ? 113 LEU C CG    1 
ATOM   9013  C CD1   . LEU C 1 113 ? -36.156 -1.295  -45.200  1.00 47.92  ? 113 LEU C CD1   1 
ATOM   9014  C CD2   . LEU C 1 113 ? -38.573 -1.477  -44.557  1.00 45.85  ? 113 LEU C CD2   1 
ATOM   9015  N N     . GLU C 1 114 ? -38.535 3.757   -46.378  1.00 49.00  ? 114 GLU C N     1 
ATOM   9016  C CA    . GLU C 1 114 ? -38.807 5.169   -46.158  1.00 48.52  ? 114 GLU C CA    1 
ATOM   9017  C C     . GLU C 1 114 ? -38.539 5.964   -47.442  1.00 43.17  ? 114 GLU C C     1 
ATOM   9018  O O     . GLU C 1 114 ? -37.633 5.685   -48.223  1.00 39.13  ? 114 GLU C O     1 
ATOM   9019  C CB    . GLU C 1 114 ? -37.966 5.680   -44.988  1.00 47.06  ? 114 GLU C CB    1 
ATOM   9020  C CG    . GLU C 1 114 ? -38.511 6.927   -44.327  1.00 58.29  ? 114 GLU C CG    1 
ATOM   9021  C CD    . GLU C 1 114 ? -37.542 7.639   -43.382  1.00 63.73  ? 114 GLU C CD    1 
ATOM   9022  O OE1   . GLU C 1 114 ? -36.493 7.035   -42.975  1.00 55.10  ? 114 GLU C OE1   1 
ATOM   9023  O OE2   . GLU C 1 114 ? -37.806 8.825   -43.082  1.00 59.80  ? 114 GLU C OE2   1 
ATOM   9024  N N     . VAL C 1 115 ? -39.374 6.964   -47.658  1.00 41.09  ? 115 VAL C N     1 
ATOM   9025  C CA    . VAL C 1 115 ? -39.050 8.058   -48.553  1.00 41.24  ? 115 VAL C CA    1 
ATOM   9026  C C     . VAL C 1 115 ? -39.369 9.348   -47.800  1.00 43.03  ? 115 VAL C C     1 
ATOM   9027  O O     . VAL C 1 115 ? -40.510 9.570   -47.394  1.00 37.94  ? 115 VAL C O     1 
ATOM   9028  C CB    . VAL C 1 115 ? -39.838 7.961   -49.871  1.00 41.66  ? 115 VAL C CB    1 
ATOM   9029  C CG1   . VAL C 1 115 ? -39.591 9.149   -50.791  1.00 42.34  ? 115 VAL C CG1   1 
ATOM   9030  C CG2   . VAL C 1 115 ? -39.541 6.653   -50.584  1.00 44.43  ? 115 VAL C CG2   1 
ATOM   9031  N N     . ASN C 1 116 ? -38.338 10.195  -47.660  1.00 52.60  ? 116 ASN C N     1 
ATOM   9032  C CA    . ASN C 1 116 ? -38.350 11.400  -46.843  1.00 42.90  ? 116 ASN C CA    1 
ATOM   9033  C C     . ASN C 1 116 ? -38.207 12.603  -47.755  1.00 37.27  ? 116 ASN C C     1 
ATOM   9034  O O     . ASN C 1 116 ? -37.173 12.762  -48.393  1.00 40.18  ? 116 ASN C O     1 
ATOM   9035  C CB    . ASN C 1 116 ? -37.199 11.384  -45.844  1.00 41.70  ? 116 ASN C CB    1 
ATOM   9036  C CG    . ASN C 1 116 ? -37.269 12.533  -44.879  1.00 42.87  ? 116 ASN C CG    1 
ATOM   9037  O OD1   . ASN C 1 116 ? -37.142 13.694  -45.264  1.00 49.57  ? 116 ASN C OD1   1 
ATOM   9038  N ND2   . ASN C 1 116 ? -37.476 12.214  -43.620  1.00 45.31  ? 116 ASN C ND2   1 
ATOM   9039  N N     . GLU C 1 117 ? -39.226 13.464  -47.777  1.00 40.25  ? 117 GLU C N     1 
ATOM   9040  C CA    . GLU C 1 117 ? -39.246 14.607  -48.677  1.00 41.91  ? 117 GLU C CA    1 
ATOM   9041  C C     . GLU C 1 117 ? -38.345 15.747  -48.167  1.00 50.86  ? 117 GLU C C     1 
ATOM   9042  O O     . GLU C 1 117 ? -37.621 16.339  -48.979  1.00 51.11  ? 117 GLU C O     1 
ATOM   9043  C CB    . GLU C 1 117 ? -40.691 15.050  -48.895  1.00 43.60  ? 117 GLU C CB    1 
ATOM   9044  C CG    . GLU C 1 117 ? -40.837 16.266  -49.809  1.00 53.78  ? 117 GLU C CG    1 
ATOM   9045  C CD    . GLU C 1 117 ? -42.284 16.681  -50.040  1.00 59.18  ? 117 GLU C CD    1 
ATOM   9046  O OE1   . GLU C 1 117 ? -43.032 16.757  -49.019  1.00 56.37  ? 117 GLU C OE1   1 
ATOM   9047  O OE2   . GLU C 1 117 ? -42.660 16.916  -51.230  1.00 49.89  ? 117 GLU C OE2   1 
ATOM   9048  N N     . GLU C 1 118 ? -38.397 16.083  -46.857  1.00 43.98  ? 118 GLU C N     1 
ATOM   9049  C CA    . GLU C 1 118 ? -37.700 17.264  -46.353  1.00 44.75  ? 118 GLU C CA    1 
ATOM   9050  C C     . GLU C 1 118 ? -36.185 17.068  -46.485  1.00 48.54  ? 118 GLU C C     1 
ATOM   9051  O O     . GLU C 1 118 ? -35.476 18.040  -46.727  1.00 50.55  ? 118 GLU C O     1 
ATOM   9052  C CB    . GLU C 1 118 ? -38.081 17.654  -44.910  1.00 48.89  ? 118 GLU C CB    1 
ATOM   9053  C CG    . GLU C 1 118 ? -37.997 16.531  -43.862  1.00 59.27  ? 118 GLU C CG    1 
ATOM   9054  C CD    . GLU C 1 118 ? -38.245 16.901  -42.398  1.00 61.48  ? 118 GLU C CD    1 
ATOM   9055  O OE1   . GLU C 1 118 ? -38.271 15.992  -41.541  1.00 61.05  ? 118 GLU C OE1   1 
ATOM   9056  O OE2   . GLU C 1 118 ? -38.409 18.095  -42.097  1.00 61.27  ? 118 GLU C OE2   1 
ATOM   9057  N N     . PHE C 1 119 ? -35.693 15.821  -46.357  1.00 44.32  ? 119 PHE C N     1 
ATOM   9058  C CA    . PHE C 1 119 ? -34.269 15.544  -46.434  1.00 40.57  ? 119 PHE C CA    1 
ATOM   9059  C C     . PHE C 1 119 ? -33.868 14.873  -47.749  1.00 46.41  ? 119 PHE C C     1 
ATOM   9060  O O     . PHE C 1 119 ? -32.685 14.589  -47.963  1.00 43.71  ? 119 PHE C O     1 
ATOM   9061  C CB    . PHE C 1 119 ? -33.835 14.635  -45.289  1.00 36.56  ? 119 PHE C CB    1 
ATOM   9062  C CG    . PHE C 1 119 ? -34.188 15.131  -43.921  1.00 37.45  ? 119 PHE C CG    1 
ATOM   9063  C CD1   . PHE C 1 119 ? -33.920 16.425  -43.544  1.00 43.27  ? 119 PHE C CD1   1 
ATOM   9064  C CD2   . PHE C 1 119 ? -34.702 14.273  -42.969  1.00 38.44  ? 119 PHE C CD2   1 
ATOM   9065  C CE1   . PHE C 1 119 ? -34.234 16.865  -42.268  1.00 43.63  ? 119 PHE C CE1   1 
ATOM   9066  C CE2   . PHE C 1 119 ? -35.015 14.710  -41.700  1.00 37.70  ? 119 PHE C CE2   1 
ATOM   9067  C CZ    . PHE C 1 119 ? -34.776 16.008  -41.348  1.00 40.39  ? 119 PHE C CZ    1 
ATOM   9068  N N     . GLY C 1 120 ? -34.850 14.577  -48.610  1.00 48.87  ? 120 GLY C N     1 
ATOM   9069  C CA    . GLY C 1 120 ? -34.576 14.060  -49.944  1.00 44.94  ? 120 GLY C CA    1 
ATOM   9070  C C     . GLY C 1 120 ? -33.821 12.731  -49.933  1.00 45.16  ? 120 GLY C C     1 
ATOM   9071  O O     . GLY C 1 120 ? -32.677 12.664  -50.363  1.00 41.30  ? 120 GLY C O     1 
ATOM   9072  N N     . TYR C 1 121 ? -34.457 11.656  -49.459  1.00 41.87  ? 121 TYR C N     1 
ATOM   9073  C CA    . TYR C 1 121 ? -33.803 10.366  -49.491  1.00 38.52  ? 121 TYR C CA    1 
ATOM   9074  C C     . TYR C 1 121 ? -34.823 9.247   -49.529  1.00 37.83  ? 121 TYR C C     1 
ATOM   9075  O O     . TYR C 1 121 ? -35.989 9.466   -49.240  1.00 39.40  ? 121 TYR C O     1 
ATOM   9076  C CB    . TYR C 1 121 ? -32.884 10.220  -48.282  1.00 41.39  ? 121 TYR C CB    1 
ATOM   9077  C CG    . TYR C 1 121 ? -33.492 10.007  -46.909  1.00 42.75  ? 121 TYR C CG    1 
ATOM   9078  C CD1   . TYR C 1 121 ? -33.991 8.776   -46.529  1.00 44.46  ? 121 TYR C CD1   1 
ATOM   9079  C CD2   . TYR C 1 121 ? -33.399 10.982  -45.920  1.00 36.87  ? 121 TYR C CD2   1 
ATOM   9080  C CE1   . TYR C 1 121 ? -34.438 8.531   -45.239  1.00 44.17  ? 121 TYR C CE1   1 
ATOM   9081  C CE2   . TYR C 1 121 ? -33.856 10.764  -44.635  1.00 40.67  ? 121 TYR C CE2   1 
ATOM   9082  C CZ    . TYR C 1 121 ? -34.369 9.524   -44.279  1.00 49.03  ? 121 TYR C CZ    1 
ATOM   9083  O OH    . TYR C 1 121 ? -34.805 9.250   -42.987  1.00 39.29  ? 121 TYR C OH    1 
ATOM   9084  N N     . ALA C 1 122 ? -34.350 8.050   -49.882  1.00 40.28  ? 122 ALA C N     1 
ATOM   9085  C CA    . ALA C 1 122 ? -35.127 6.831   -49.707  1.00 43.67  ? 122 ALA C CA    1 
ATOM   9086  C C     . ALA C 1 122 ? -34.280 5.717   -49.117  1.00 36.97  ? 122 ALA C C     1 
ATOM   9087  O O     . ALA C 1 122 ? -33.081 5.669   -49.322  1.00 40.00  ? 122 ALA C O     1 
ATOM   9088  C CB    . ALA C 1 122 ? -35.710 6.366   -51.016  1.00 47.13  ? 122 ALA C CB    1 
ATOM   9089  N N     . LEU C 1 123 ? -34.964 4.796   -48.441  1.00 38.56  ? 123 LEU C N     1 
ATOM   9090  C CA    . LEU C 1 123 ? -34.387 3.565   -47.930  1.00 38.19  ? 123 LEU C CA    1 
ATOM   9091  C C     . LEU C 1 123 ? -35.178 2.411   -48.542  1.00 40.32  ? 123 LEU C C     1 
ATOM   9092  O O     . LEU C 1 123 ? -36.405 2.385   -48.407  1.00 48.55  ? 123 LEU C O     1 
ATOM   9093  C CB    . LEU C 1 123 ? -34.497 3.571   -46.399  1.00 33.86  ? 123 LEU C CB    1 
ATOM   9094  C CG    . LEU C 1 123 ? -34.025 2.312   -45.676  1.00 33.50  ? 123 LEU C CG    1 
ATOM   9095  C CD1   . LEU C 1 123 ? -32.517 2.087   -45.871  1.00 32.57  ? 123 LEU C CD1   1 
ATOM   9096  C CD2   . LEU C 1 123 ? -34.372 2.388   -44.199  1.00 31.86  ? 123 LEU C CD2   1 
ATOM   9097  N N     . VAL C 1 124 ? -34.475 1.493   -49.217  1.00 32.84  ? 124 VAL C N     1 
ATOM   9098  C CA    . VAL C 1 124 ? -35.091 0.528   -50.110  1.00 32.47  ? 124 VAL C CA    1 
ATOM   9099  C C     . VAL C 1 124 ? -34.442 -0.839  -49.932  1.00 35.33  ? 124 VAL C C     1 
ATOM   9100  O O     . VAL C 1 124 ? -33.248 -0.946  -49.658  1.00 37.86  ? 124 VAL C O     1 
ATOM   9101  C CB    . VAL C 1 124 ? -34.993 0.978   -51.582  1.00 35.42  ? 124 VAL C CB    1 
ATOM   9102  C CG1   . VAL C 1 124 ? -36.002 2.048   -51.964  1.00 33.62  ? 124 VAL C CG1   1 
ATOM   9103  C CG2   . VAL C 1 124 ? -33.600 1.453   -51.941  1.00 40.08  ? 124 VAL C CG2   1 
ATOM   9104  N N     . GLU C 1 125 ? -35.249 -1.888  -50.125  1.00 40.35  ? 125 GLU C N     1 
ATOM   9105  C CA    . GLU C 1 125 ? -34.749 -3.251  -50.224  1.00 43.76  ? 125 GLU C CA    1 
ATOM   9106  C C     . GLU C 1 125 ? -34.354 -3.540  -51.676  1.00 40.25  ? 125 GLU C C     1 
ATOM   9107  O O     . GLU C 1 125 ? -34.697 -2.806  -52.605  1.00 37.53  ? 125 GLU C O     1 
ATOM   9108  C CB    . GLU C 1 125 ? -35.805 -4.227  -49.707  1.00 50.03  ? 125 GLU C CB    1 
ATOM   9109  C CG    . GLU C 1 125 ? -36.159 -4.019  -48.242  1.00 55.85  ? 125 GLU C CG    1 
ATOM   9110  C CD    . GLU C 1 125 ? -37.004 -5.120  -47.610  1.00 60.27  ? 125 GLU C CD    1 
ATOM   9111  O OE1   . GLU C 1 125 ? -38.068 -5.523  -48.203  1.00 62.77  ? 125 GLU C OE1   1 
ATOM   9112  O OE2   . GLU C 1 125 ? -36.609 -5.569  -46.523  1.00 56.28  ? 125 GLU C OE2   1 
ATOM   9113  N N     . PRO C 1 126 ? -33.557 -4.588  -51.934  1.00 37.88  ? 126 PRO C N     1 
ATOM   9114  C CA    . PRO C 1 126 ? -33.005 -4.797  -53.270  1.00 44.46  ? 126 PRO C CA    1 
ATOM   9115  C C     . PRO C 1 126 ? -34.049 -4.948  -54.375  1.00 49.92  ? 126 PRO C C     1 
ATOM   9116  O O     . PRO C 1 126 ? -33.797 -4.531  -55.501  1.00 53.17  ? 126 PRO C O     1 
ATOM   9117  C CB    . PRO C 1 126 ? -32.203 -6.098  -53.101  1.00 47.55  ? 126 PRO C CB    1 
ATOM   9118  C CG    . PRO C 1 126 ? -31.857 -6.086  -51.620  1.00 43.93  ? 126 PRO C CG    1 
ATOM   9119  C CD    . PRO C 1 126 ? -33.141 -5.611  -50.976  1.00 38.52  ? 126 PRO C CD    1 
ATOM   9120  N N     . GLY C 1 127 ? -35.207 -5.540  -54.039  1.00 46.80  ? 127 GLY C N     1 
ATOM   9121  C CA    . GLY C 1 127 ? -36.240 -5.874  -55.003  1.00 43.42  ? 127 GLY C CA    1 
ATOM   9122  C C     . GLY C 1 127 ? -36.992 -4.667  -55.550  1.00 47.75  ? 127 GLY C C     1 
ATOM   9123  O O     . GLY C 1 127 ? -37.717 -4.768  -56.540  1.00 52.54  ? 127 GLY C O     1 
ATOM   9124  N N     . VAL C 1 128 ? -36.858 -3.515  -54.908  1.00 48.05  ? 128 VAL C N     1 
ATOM   9125  C CA    . VAL C 1 128 ? -37.535 -2.343  -55.420  1.00 47.41  ? 128 VAL C CA    1 
ATOM   9126  C C     . VAL C 1 128 ? -36.940 -1.970  -56.771  1.00 53.05  ? 128 VAL C C     1 
ATOM   9127  O O     . VAL C 1 128 ? -35.725 -1.864  -56.915  1.00 57.85  ? 128 VAL C O     1 
ATOM   9128  C CB    . VAL C 1 128 ? -37.435 -1.159  -54.453  1.00 47.10  ? 128 VAL C CB    1 
ATOM   9129  C CG1   . VAL C 1 128 ? -38.071 0.083   -55.065  1.00 44.55  ? 128 VAL C CG1   1 
ATOM   9130  C CG2   . VAL C 1 128 ? -38.026 -1.486  -53.089  1.00 43.76  ? 128 VAL C CG2   1 
ATOM   9131  N N     . SER C 1 129 ? -37.826 -1.759  -57.746  1.00 58.72  ? 129 SER C N     1 
ATOM   9132  C CA    . SER C 1 129 ? -37.442 -1.298  -59.071  1.00 58.15  ? 129 SER C CA    1 
ATOM   9133  C C     . SER C 1 129 ? -37.560 0.223   -59.128  1.00 50.14  ? 129 SER C C     1 
ATOM   9134  O O     . SER C 1 129 ? -38.229 0.821   -58.304  1.00 41.69  ? 129 SER C O     1 
ATOM   9135  C CB    . SER C 1 129 ? -38.323 -1.921  -60.127  1.00 52.93  ? 129 SER C CB    1 
ATOM   9136  O OG    . SER C 1 129 ? -39.628 -1.338  -60.062  1.00 52.68  ? 129 SER C OG    1 
ATOM   9137  N N     . TYR C 1 130 ? -36.992 0.813   -60.183  1.00 47.62  ? 130 TYR C N     1 
ATOM   9138  C CA    . TYR C 1 130 ? -37.199 2.210   -60.489  1.00 47.80  ? 130 TYR C CA    1 
ATOM   9139  C C     . TYR C 1 130 ? -38.689 2.487   -60.668  1.00 49.28  ? 130 TYR C C     1 
ATOM   9140  O O     . TYR C 1 130 ? -39.193 3.469   -60.125  1.00 54.70  ? 130 TYR C O     1 
ATOM   9141  C CB    . TYR C 1 130 ? -36.340 2.586   -61.691  1.00 45.33  ? 130 TYR C CB    1 
ATOM   9142  C CG    . TYR C 1 130 ? -34.857 2.489   -61.427  1.00 44.62  ? 130 TYR C CG    1 
ATOM   9143  C CD1   . TYR C 1 130 ? -34.208 3.467   -60.695  1.00 47.43  ? 130 TYR C CD1   1 
ATOM   9144  C CD2   . TYR C 1 130 ? -34.095 1.440   -61.910  1.00 45.51  ? 130 TYR C CD2   1 
ATOM   9145  C CE1   . TYR C 1 130 ? -32.851 3.417   -60.450  1.00 48.47  ? 130 TYR C CE1   1 
ATOM   9146  C CE2   . TYR C 1 130 ? -32.730 1.377   -61.683  1.00 49.15  ? 130 TYR C CE2   1 
ATOM   9147  C CZ    . TYR C 1 130 ? -32.104 2.351   -60.919  1.00 53.97  ? 130 TYR C CZ    1 
ATOM   9148  O OH    . TYR C 1 130 ? -30.741 2.326   -60.640  1.00 45.92  ? 130 TYR C OH    1 
ATOM   9149  N N     . PHE C 1 131 ? -39.395 1.610   -61.389  1.00 50.25  ? 131 PHE C N     1 
ATOM   9150  C CA    . PHE C 1 131 ? -40.813 1.820   -61.665  1.00 53.45  ? 131 PHE C CA    1 
ATOM   9151  C C     . PHE C 1 131 ? -41.561 1.921   -60.347  1.00 49.24  ? 131 PHE C C     1 
ATOM   9152  O O     . PHE C 1 131 ? -42.300 2.876   -60.123  1.00 41.81  ? 131 PHE C O     1 
ATOM   9153  C CB    . PHE C 1 131 ? -41.432 0.714   -62.537  1.00 54.59  ? 131 PHE C CB    1 
ATOM   9154  C CG    . PHE C 1 131 ? -41.166 0.868   -64.012  1.00 50.92  ? 131 PHE C CG    1 
ATOM   9155  C CD1   . PHE C 1 131 ? -41.652 1.965   -64.705  1.00 61.29  ? 131 PHE C CD1   1 
ATOM   9156  C CD2   . PHE C 1 131 ? -40.391 -0.047  -64.702  1.00 55.34  ? 131 PHE C CD2   1 
ATOM   9157  C CE1   . PHE C 1 131 ? -41.365 2.143   -66.054  1.00 62.75  ? 131 PHE C CE1   1 
ATOM   9158  C CE2   . PHE C 1 131 ? -40.114 0.121   -66.054  1.00 58.65  ? 131 PHE C CE2   1 
ATOM   9159  C CZ    . PHE C 1 131 ? -40.589 1.222   -66.727  1.00 60.25  ? 131 PHE C CZ    1 
ATOM   9160  N N     . GLU C 1 132 ? -41.329 0.941   -59.469  1.00 54.81  ? 132 GLU C N     1 
ATOM   9161  C CA    . GLU C 1 132 ? -41.977 0.941   -58.166  1.00 58.70  ? 132 GLU C CA    1 
ATOM   9162  C C     . GLU C 1 132 ? -41.732 2.252   -57.398  1.00 63.05  ? 132 GLU C C     1 
ATOM   9163  O O     . GLU C 1 132 ? -42.667 2.748   -56.770  1.00 58.95  ? 132 GLU C O     1 
ATOM   9164  C CB    . GLU C 1 132 ? -41.517 -0.270  -57.364  1.00 61.11  ? 132 GLU C CB    1 
ATOM   9165  C CG    . GLU C 1 132 ? -42.166 -1.567  -57.787  1.00 67.76  ? 132 GLU C CG    1 
ATOM   9166  C CD    . GLU C 1 132 ? -41.552 -2.753  -57.063  1.00 82.18  ? 132 GLU C CD    1 
ATOM   9167  O OE1   . GLU C 1 132 ? -41.458 -2.713  -55.790  1.00 88.19  ? 132 GLU C OE1   1 
ATOM   9168  O OE2   . GLU C 1 132 ? -41.125 -3.689  -57.761  1.00 73.05  ? 132 GLU C OE2   1 
ATOM   9169  N N     . LEU C 1 133 ? -40.496 2.804   -57.443  1.00 56.54  ? 133 LEU C N     1 
ATOM   9170  C CA    . LEU C 1 133 ? -40.095 3.933   -56.609  1.00 51.65  ? 133 LEU C CA    1 
ATOM   9171  C C     . LEU C 1 133 ? -40.627 5.246   -57.184  1.00 52.98  ? 133 LEU C C     1 
ATOM   9172  O O     . LEU C 1 133 ? -41.095 6.098   -56.426  1.00 50.88  ? 133 LEU C O     1 
ATOM   9173  C CB    . LEU C 1 133 ? -38.563 3.972   -56.471  1.00 54.83  ? 133 LEU C CB    1 
ATOM   9174  C CG    . LEU C 1 133 ? -37.982 5.118   -55.627  1.00 52.72  ? 133 LEU C CG    1 
ATOM   9175  C CD1   . LEU C 1 133 ? -38.413 5.013   -54.166  1.00 47.71  ? 133 LEU C CD1   1 
ATOM   9176  C CD2   . LEU C 1 133 ? -36.456 5.154   -55.715  1.00 51.00  ? 133 LEU C CD2   1 
ATOM   9177  N N     . TYR C 1 134 ? -40.532 5.415   -58.511  1.00 46.10  ? 134 TYR C N     1 
ATOM   9178  C CA    . TYR C 1 134 ? -41.215 6.506   -59.183  1.00 52.88  ? 134 TYR C CA    1 
ATOM   9179  C C     . TYR C 1 134 ? -42.711 6.526   -58.829  1.00 58.29  ? 134 TYR C C     1 
ATOM   9180  O O     . TYR C 1 134 ? -43.248 7.568   -58.465  1.00 59.56  ? 134 TYR C O     1 
ATOM   9181  C CB    . TYR C 1 134 ? -41.052 6.373   -60.697  1.00 56.68  ? 134 TYR C CB    1 
ATOM   9182  C CG    . TYR C 1 134 ? -41.599 7.542   -61.467  1.00 61.36  ? 134 TYR C CG    1 
ATOM   9183  C CD1   . TYR C 1 134 ? -40.849 8.696   -61.610  1.00 62.76  ? 134 TYR C CD1   1 
ATOM   9184  C CD2   . TYR C 1 134 ? -42.859 7.507   -62.052  1.00 65.17  ? 134 TYR C CD2   1 
ATOM   9185  C CE1   . TYR C 1 134 ? -41.314 9.778   -62.337  1.00 68.19  ? 134 TYR C CE1   1 
ATOM   9186  C CE2   . TYR C 1 134 ? -43.342 8.583   -62.788  1.00 63.80  ? 134 TYR C CE2   1 
ATOM   9187  C CZ    . TYR C 1 134 ? -42.566 9.724   -62.923  1.00 68.41  ? 134 TYR C CZ    1 
ATOM   9188  O OH    . TYR C 1 134 ? -42.985 10.834  -63.599  1.00 63.08  ? 134 TYR C OH    1 
ATOM   9189  N N     . ASP C 1 135 ? -43.371 5.360   -58.911  1.00 56.31  ? 135 ASP C N     1 
ATOM   9190  C CA    . ASP C 1 135 ? -44.806 5.243   -58.692  1.00 60.55  ? 135 ASP C CA    1 
ATOM   9191  C C     . ASP C 1 135 ? -45.172 5.482   -57.225  1.00 56.98  ? 135 ASP C C     1 
ATOM   9192  O O     . ASP C 1 135 ? -46.227 6.036   -56.971  1.00 53.10  ? 135 ASP C O     1 
ATOM   9193  C CB    . ASP C 1 135 ? -45.326 3.915   -59.262  1.00 60.08  ? 135 ASP C CB    1 
ATOM   9194  C CG    . ASP C 1 135 ? -45.223 3.869   -60.787  1.00 63.63  ? 135 ASP C CG    1 
ATOM   9195  O OD1   . ASP C 1 135 ? -45.170 4.956   -61.408  1.00 61.02  ? 135 ASP C OD1   1 
ATOM   9196  O OD2   . ASP C 1 135 ? -45.137 2.757   -61.355  1.00 66.23  ? 135 ASP C OD2   1 
ATOM   9197  N N     . TYR C 1 136 ? -44.300 5.114   -56.270  1.00 61.79  ? 136 TYR C N     1 
ATOM   9198  C CA    . TYR C 1 136 ? -44.520 5.379   -54.854  1.00 51.97  ? 136 TYR C CA    1 
ATOM   9199  C C     . TYR C 1 136 ? -44.419 6.867   -54.603  1.00 56.66  ? 136 TYR C C     1 
ATOM   9200  O O     . TYR C 1 136 ? -45.295 7.437   -53.973  1.00 62.68  ? 136 TYR C O     1 
ATOM   9201  C CB    . TYR C 1 136 ? -43.459 4.736   -53.971  1.00 56.19  ? 136 TYR C CB    1 
ATOM   9202  C CG    . TYR C 1 136 ? -43.682 4.889   -52.485  1.00 66.29  ? 136 TYR C CG    1 
ATOM   9203  C CD1   . TYR C 1 136 ? -44.490 3.995   -51.791  1.00 68.91  ? 136 TYR C CD1   1 
ATOM   9204  C CD2   . TYR C 1 136 ? -43.081 5.909   -51.762  1.00 55.68  ? 136 TYR C CD2   1 
ATOM   9205  C CE1   . TYR C 1 136 ? -44.695 4.104   -50.426  1.00 68.20  ? 136 TYR C CE1   1 
ATOM   9206  C CE2   . TYR C 1 136 ? -43.271 6.028   -50.393  1.00 57.13  ? 136 TYR C CE2   1 
ATOM   9207  C CZ    . TYR C 1 136 ? -44.082 5.125   -49.724  1.00 67.68  ? 136 TYR C CZ    1 
ATOM   9208  O OH    . TYR C 1 136 ? -44.284 5.200   -48.371  1.00 68.15  ? 136 TYR C OH    1 
ATOM   9209  N N     . ILE C 1 137 ? -43.363 7.482   -55.145  1.00 52.89  ? 137 ILE C N     1 
ATOM   9210  C CA    . ILE C 1 137 ? -43.170 8.917   -55.012  1.00 51.11  ? 137 ILE C CA    1 
ATOM   9211  C C     . ILE C 1 137 ? -44.378 9.685   -55.562  1.00 59.04  ? 137 ILE C C     1 
ATOM   9212  O O     . ILE C 1 137 ? -44.748 10.735  -55.026  1.00 66.16  ? 137 ILE C O     1 
ATOM   9213  C CB    . ILE C 1 137 ? -41.825 9.337   -55.657  1.00 50.55  ? 137 ILE C CB    1 
ATOM   9214  C CG1   . ILE C 1 137 ? -40.644 8.890   -54.792  1.00 49.51  ? 137 ILE C CG1   1 
ATOM   9215  C CG2   . ILE C 1 137 ? -41.732 10.837  -55.926  1.00 51.13  ? 137 ILE C CG2   1 
ATOM   9216  C CD1   . ILE C 1 137 ? -39.325 8.867   -55.486  1.00 46.31  ? 137 ILE C CD1   1 
ATOM   9217  N N     . GLN C 1 138 ? -44.974 9.207   -56.661  1.00 70.36  ? 138 GLN C N     1 
ATOM   9218  C CA    . GLN C 1 138 ? -46.024 9.965   -57.335  1.00 67.24  ? 138 GLN C CA    1 
ATOM   9219  C C     . GLN C 1 138 ? -47.340 9.816   -56.563  1.00 65.09  ? 138 GLN C C     1 
ATOM   9220  O O     . GLN C 1 138 ? -48.002 10.809  -56.272  1.00 68.64  ? 138 GLN C O     1 
ATOM   9221  C CB    . GLN C 1 138 ? -46.063 9.571   -58.809  1.00 58.44  ? 138 GLN C CB    1 
ATOM   9222  C CG    . GLN C 1 138 ? -44.722 9.802   -59.506  1.00 64.53  ? 138 GLN C CG    1 
ATOM   9223  C CD    . GLN C 1 138 ? -44.382 11.247  -59.797  1.00 70.16  ? 138 GLN C CD    1 
ATOM   9224  O OE1   . GLN C 1 138 ? -45.205 12.139  -59.635  1.00 70.38  ? 138 GLN C OE1   1 
ATOM   9225  N NE2   . GLN C 1 138 ? -43.165 11.497  -60.262  1.00 72.91  ? 138 GLN C NE2   1 
ATOM   9226  N N     . GLU C 1 139 ? -47.672 8.598   -56.139  1.00 60.67  ? 139 GLU C N     1 
ATOM   9227  C CA    . GLU C 1 139 ? -48.814 8.387   -55.264  1.00 71.52  ? 139 GLU C CA    1 
ATOM   9228  C C     . GLU C 1 139 ? -48.826 9.406   -54.125  1.00 76.75  ? 139 GLU C C     1 
ATOM   9229  O O     . GLU C 1 139 ? -49.797 10.153  -53.969  1.00 77.51  ? 139 GLU C O     1 
ATOM   9230  C CB    . GLU C 1 139 ? -48.803 6.987   -54.646  1.00 75.18  ? 139 GLU C CB    1 
ATOM   9231  C CG    . GLU C 1 139 ? -49.551 5.951   -55.463  1.00 82.75  ? 139 GLU C CG    1 
ATOM   9232  C CD    . GLU C 1 139 ? -49.390 4.512   -54.994  1.00 99.37  ? 139 GLU C CD    1 
ATOM   9233  O OE1   . GLU C 1 139 ? -50.131 3.644   -55.511  1.00 95.88  ? 139 GLU C OE1   1 
ATOM   9234  O OE2   . GLU C 1 139 ? -48.518 4.255   -54.122  1.00 106.87 ? 139 GLU C OE2   1 
ATOM   9235  N N     . LYS C 1 140 ? -47.750 9.407   -53.324  1.00 70.65  ? 140 LYS C N     1 
ATOM   9236  C CA    . LYS C 1 140 ? -47.718 10.142  -52.066  1.00 71.88  ? 140 LYS C CA    1 
ATOM   9237  C C     . LYS C 1 140 ? -47.479 11.632  -52.321  1.00 62.32  ? 140 LYS C C     1 
ATOM   9238  O O     . LYS C 1 140 ? -47.472 12.394  -51.359  1.00 60.31  ? 140 LYS C O     1 
ATOM   9239  C CB    . LYS C 1 140 ? -46.631 9.635   -51.099  1.00 73.25  ? 140 LYS C CB    1 
ATOM   9240  C CG    . LYS C 1 140 ? -46.704 8.173   -50.667  1.00 74.65  ? 140 LYS C CG    1 
ATOM   9241  C CD    . LYS C 1 140 ? -47.700 7.857   -49.571  1.00 80.06  ? 140 LYS C CD    1 
ATOM   9242  C CE    . LYS C 1 140 ? -48.143 6.405   -49.622  1.00 85.97  ? 140 LYS C CE    1 
ATOM   9243  N NZ    . LYS C 1 140 ? -48.702 5.934   -48.336  1.00 78.21  ? 140 LYS C NZ    1 
ATOM   9244  N N     . GLY C 1 141 ? -47.227 12.026  -53.581  1.00 58.26  ? 141 GLY C N     1 
ATOM   9245  C CA    . GLY C 1 141 ? -47.185 13.431  -53.972  1.00 64.24  ? 141 GLY C CA    1 
ATOM   9246  C C     . GLY C 1 141 ? -45.889 14.147  -53.573  1.00 66.30  ? 141 GLY C C     1 
ATOM   9247  O O     . GLY C 1 141 ? -45.806 15.373  -53.595  1.00 62.05  ? 141 GLY C O     1 
ATOM   9248  N N     . LEU C 1 142 ? -44.845 13.371  -53.285  1.00 63.33  ? 142 LEU C N     1 
ATOM   9249  C CA    . LEU C 1 142 ? -43.585 13.903  -52.801  1.00 56.19  ? 142 LEU C CA    1 
ATOM   9250  C C     . LEU C 1 142 ? -42.844 14.577  -53.955  1.00 55.43  ? 142 LEU C C     1 
ATOM   9251  O O     . LEU C 1 142 ? -42.761 14.013  -55.029  1.00 46.56  ? 142 LEU C O     1 
ATOM   9252  C CB    . LEU C 1 142 ? -42.796 12.725  -52.225  1.00 61.01  ? 142 LEU C CB    1 
ATOM   9253  C CG    . LEU C 1 142 ? -43.531 11.885  -51.167  1.00 60.25  ? 142 LEU C CG    1 
ATOM   9254  C CD1   . LEU C 1 142 ? -42.662 10.727  -50.666  1.00 57.00  ? 142 LEU C CD1   1 
ATOM   9255  C CD2   . LEU C 1 142 ? -44.001 12.745  -49.997  1.00 54.16  ? 142 LEU C CD2   1 
ATOM   9256  N N     . LYS C 1 143 ? -42.290 15.773  -53.709  1.00 60.03  ? 143 LYS C N     1 
ATOM   9257  C CA    . LYS C 1 143 ? -41.602 16.568  -54.707  1.00 52.06  ? 143 LYS C CA    1 
ATOM   9258  C C     . LYS C 1 143 ? -40.129 16.168  -54.813  1.00 56.94  ? 143 LYS C C     1 
ATOM   9259  O O     . LYS C 1 143 ? -39.232 16.952  -54.479  1.00 53.37  ? 143 LYS C O     1 
ATOM   9260  C CB    . LYS C 1 143 ? -41.682 18.043  -54.317  1.00 60.04  ? 143 LYS C CB    1 
ATOM   9261  C CG    . LYS C 1 143 ? -43.084 18.589  -54.158  1.00 71.58  ? 143 LYS C CG    1 
ATOM   9262  C CD    . LYS C 1 143 ? -43.140 20.050  -53.779  1.00 84.76  ? 143 LYS C CD    1 
ATOM   9263  C CE    . LYS C 1 143 ? -44.418 20.392  -53.033  1.00 97.98  ? 143 LYS C CE    1 
ATOM   9264  N NZ    . LYS C 1 143 ? -44.961 21.716  -53.423  1.00 111.43 ? 143 LYS C NZ    1 
ATOM   9265  N N     . LEU C 1 144 ? -39.888 14.958  -55.333  1.00 56.30  ? 144 LEU C N     1 
ATOM   9266  C CA    . LEU C 1 144 ? -38.548 14.395  -55.451  1.00 54.38  ? 144 LEU C CA    1 
ATOM   9267  C C     . LEU C 1 144 ? -38.413 13.802  -56.839  1.00 55.43  ? 144 LEU C C     1 
ATOM   9268  O O     . LEU C 1 144 ? -39.413 13.350  -57.380  1.00 49.98  ? 144 LEU C O     1 
ATOM   9269  C CB    . LEU C 1 144 ? -38.368 13.276  -54.426  1.00 51.50  ? 144 LEU C CB    1 
ATOM   9270  C CG    . LEU C 1 144 ? -38.523 13.669  -52.955  1.00 55.64  ? 144 LEU C CG    1 
ATOM   9271  C CD1   . LEU C 1 144 ? -38.563 12.429  -52.077  1.00 55.58  ? 144 LEU C CD1   1 
ATOM   9272  C CD2   . LEU C 1 144 ? -37.390 14.588  -52.507  1.00 56.45  ? 144 LEU C CD2   1 
ATOM   9273  N N     . TRP C 1 145 ? -37.191 13.806  -57.389  1.00 51.02  ? 145 TRP C N     1 
ATOM   9274  C CA    . TRP C 1 145 ? -36.866 12.986  -58.544  1.00 45.33  ? 145 TRP C CA    1 
ATOM   9275  C C     . TRP C 1 145 ? -35.969 11.815  -58.173  1.00 42.05  ? 145 TRP C C     1 
ATOM   9276  O O     . TRP C 1 145 ? -35.097 11.910  -57.326  1.00 49.84  ? 145 TRP C O     1 
ATOM   9277  C CB    . TRP C 1 145 ? -36.183 13.801  -59.630  1.00 49.49  ? 145 TRP C CB    1 
ATOM   9278  C CG    . TRP C 1 145 ? -37.041 14.834  -60.289  1.00 51.07  ? 145 TRP C CG    1 
ATOM   9279  C CD1   . TRP C 1 145 ? -38.333 15.165  -60.009  1.00 51.90  ? 145 TRP C CD1   1 
ATOM   9280  C CD2   . TRP C 1 145 ? -36.634 15.677  -61.377  1.00 52.75  ? 145 TRP C CD2   1 
ATOM   9281  N NE1   . TRP C 1 145 ? -38.748 16.174  -60.836  1.00 57.56  ? 145 TRP C NE1   1 
ATOM   9282  C CE2   . TRP C 1 145 ? -37.729 16.507  -61.687  1.00 52.41  ? 145 TRP C CE2   1 
ATOM   9283  C CE3   . TRP C 1 145 ? -35.440 15.833  -62.090  1.00 62.76  ? 145 TRP C CE3   1 
ATOM   9284  C CZ2   . TRP C 1 145 ? -37.671 17.465  -62.696  1.00 55.11  ? 145 TRP C CZ2   1 
ATOM   9285  C CZ3   . TRP C 1 145 ? -35.389 16.776  -63.099  1.00 65.85  ? 145 TRP C CZ3   1 
ATOM   9286  C CH2   . TRP C 1 145 ? -36.491 17.578  -63.396  1.00 56.67  ? 145 TRP C CH2   1 
ATOM   9287  N N     . ILE C 1 146 ? -36.149 10.721  -58.902  1.00 48.41  ? 146 ILE C N     1 
ATOM   9288  C CA    . ILE C 1 146 ? -35.223 9.606   -58.909  1.00 46.29  ? 146 ILE C CA    1 
ATOM   9289  C C     . ILE C 1 146 ? -34.300 9.793   -60.111  1.00 48.74  ? 146 ILE C C     1 
ATOM   9290  O O     . ILE C 1 146 ? -34.514 10.687  -60.921  1.00 46.13  ? 146 ILE C O     1 
ATOM   9291  C CB    . ILE C 1 146 ? -35.991 8.274   -58.938  1.00 49.86  ? 146 ILE C CB    1 
ATOM   9292  C CG1   . ILE C 1 146 ? -36.760 8.067   -60.243  1.00 53.24  ? 146 ILE C CG1   1 
ATOM   9293  C CG2   . ILE C 1 146 ? -36.917 8.153   -57.736  1.00 53.86  ? 146 ILE C CG2   1 
ATOM   9294  C CD1   . ILE C 1 146 ? -37.267 6.656   -60.425  1.00 58.72  ? 146 ILE C CD1   1 
ATOM   9295  N N     . ASP C 1 147 ? -33.244 8.980   -60.191  1.00 50.49  ? 147 ASP C N     1 
ATOM   9296  C CA    . ASP C 1 147 ? -32.330 9.032   -61.310  1.00 48.76  ? 147 ASP C CA    1 
ATOM   9297  C C     . ASP C 1 147 ? -32.223 7.630   -61.903  1.00 51.18  ? 147 ASP C C     1 
ATOM   9298  O O     . ASP C 1 147 ? -31.737 6.699   -61.251  1.00 63.48  ? 147 ASP C O     1 
ATOM   9299  C CB    . ASP C 1 147 ? -30.978 9.615   -60.900  1.00 49.36  ? 147 ASP C CB    1 
ATOM   9300  C CG    . ASP C 1 147 ? -30.008 9.710   -62.073  1.00 47.44  ? 147 ASP C CG    1 
ATOM   9301  O OD1   . ASP C 1 147 ? -29.561 8.631   -62.570  1.00 46.53  ? 147 ASP C OD1   1 
ATOM   9302  O OD2   . ASP C 1 147 ? -29.701 10.843  -62.484  1.00 36.89  ? 147 ASP C OD2   1 
ATOM   9303  N N     . VAL C 1 148 ? -32.632 7.507   -63.172  1.00 49.37  ? 148 VAL C N     1 
ATOM   9304  C CA    . VAL C 1 148 ? -32.882 6.192   -63.745  1.00 53.09  ? 148 VAL C CA    1 
ATOM   9305  C C     . VAL C 1 148 ? -31.892 5.908   -64.863  1.00 49.39  ? 148 VAL C C     1 
ATOM   9306  O O     . VAL C 1 148 ? -31.482 6.809   -65.594  1.00 52.07  ? 148 VAL C O     1 
ATOM   9307  C CB    . VAL C 1 148 ? -34.325 6.044   -64.261  1.00 50.25  ? 148 VAL C CB    1 
ATOM   9308  C CG1   . VAL C 1 148 ? -35.328 6.340   -63.158  1.00 51.81  ? 148 VAL C CG1   1 
ATOM   9309  C CG2   . VAL C 1 148 ? -34.569 6.929   -65.479  1.00 54.28  ? 148 VAL C CG2   1 
ATOM   9310  N N     . PRO C 1 149 ? -31.517 4.627   -65.021  1.00 50.05  ? 149 PRO C N     1 
ATOM   9311  C CA    . PRO C 1 149 ? -30.894 4.141   -66.252  1.00 60.53  ? 149 PRO C CA    1 
ATOM   9312  C C     . PRO C 1 149 ? -31.933 4.073   -67.376  1.00 61.35  ? 149 PRO C C     1 
ATOM   9313  O O     . PRO C 1 149 ? -33.071 4.485   -67.190  1.00 66.77  ? 149 PRO C O     1 
ATOM   9314  C CB    . PRO C 1 149 ? -30.381 2.760   -65.816  1.00 57.33  ? 149 PRO C CB    1 
ATOM   9315  C CG    . PRO C 1 149 ? -31.389 2.295   -64.809  1.00 58.61  ? 149 PRO C CG    1 
ATOM   9316  C CD    . PRO C 1 149 ? -31.741 3.557   -64.044  1.00 56.08  ? 149 PRO C CD    1 
ATOM   9317  N N     . ASP C 1 150 ? -31.568 3.539   -68.542  1.00 67.41  ? 150 ASP C N     1 
ATOM   9318  C CA    . ASP C 1 150 ? -32.520 3.435   -69.637  1.00 75.45  ? 150 ASP C CA    1 
ATOM   9319  C C     . ASP C 1 150 ? -33.657 2.478   -69.277  1.00 84.88  ? 150 ASP C C     1 
ATOM   9320  O O     . ASP C 1 150 ? -34.825 2.808   -69.485  1.00 88.38  ? 150 ASP C O     1 
ATOM   9321  C CB    . ASP C 1 150 ? -31.812 3.113   -70.950  1.00 85.68  ? 150 ASP C CB    1 
ATOM   9322  C CG    . ASP C 1 150 ? -31.300 4.381   -71.624  1.00 101.31 ? 150 ASP C CG    1 
ATOM   9323  O OD1   . ASP C 1 150 ? -32.150 5.174   -72.139  1.00 89.77  ? 150 ASP C OD1   1 
ATOM   9324  O OD2   . ASP C 1 150 ? -30.062 4.600   -71.591  1.00 97.96  ? 150 ASP C OD2   1 
ATOM   9325  N N     . GLY C 1 151 ? -33.337 1.325   -68.682  1.00 79.06  ? 151 GLY C N     1 
ATOM   9326  C CA    . GLY C 1 151 ? -34.388 0.409   -68.259  1.00 80.08  ? 151 GLY C CA    1 
ATOM   9327  C C     . GLY C 1 151 ? -34.845 0.617   -66.811  1.00 74.70  ? 151 GLY C C     1 
ATOM   9328  O O     . GLY C 1 151 ? -34.075 0.380   -65.876  1.00 79.50  ? 151 GLY C O     1 
ATOM   9329  N N     . GLY C 1 152 ? -36.139 0.937   -66.657  1.00 63.14  ? 152 GLY C N     1 
ATOM   9330  C CA    . GLY C 1 152 ? -36.759 1.228   -65.378  1.00 62.57  ? 152 GLY C CA    1 
ATOM   9331  C C     . GLY C 1 152 ? -37.070 -0.007  -64.524  1.00 63.79  ? 152 GLY C C     1 
ATOM   9332  O O     . GLY C 1 152 ? -37.462 0.130   -63.366  1.00 65.56  ? 152 GLY C O     1 
ATOM   9333  N N     . TRP C 1 153 ? -36.871 -1.209  -65.071  1.00 62.28  ? 153 TRP C N     1 
ATOM   9334  C CA    . TRP C 1 153 ? -37.310 -2.454  -64.438  1.00 73.52  ? 153 TRP C CA    1 
ATOM   9335  C C     . TRP C 1 153 ? -36.209 -2.966  -63.512  1.00 63.02  ? 153 TRP C C     1 
ATOM   9336  O O     . TRP C 1 153 ? -36.423 -3.956  -62.808  1.00 60.10  ? 153 TRP C O     1 
ATOM   9337  C CB    . TRP C 1 153 ? -37.680 -3.520  -65.499  1.00 79.78  ? 153 TRP C CB    1 
ATOM   9338  C CG    . TRP C 1 153 ? -36.665 -3.497  -66.603  1.00 101.58 ? 153 TRP C CG    1 
ATOM   9339  C CD1   . TRP C 1 153 ? -35.339 -3.831  -66.525  1.00 109.10 ? 153 TRP C CD1   1 
ATOM   9340  C CD2   . TRP C 1 153 ? -36.845 -2.917  -67.906  1.00 94.46  ? 153 TRP C CD2   1 
ATOM   9341  N NE1   . TRP C 1 153 ? -34.699 -3.551  -67.704  1.00 97.37  ? 153 TRP C NE1   1 
ATOM   9342  C CE2   . TRP C 1 153 ? -35.603 -2.986  -68.563  1.00 87.85  ? 153 TRP C CE2   1 
ATOM   9343  C CE3   . TRP C 1 153 ? -37.938 -2.359  -68.572  1.00 87.68  ? 153 TRP C CE3   1 
ATOM   9344  C CZ2   . TRP C 1 153 ? -35.444 -2.550  -69.869  1.00 101.39 ? 153 TRP C CZ2   1 
ATOM   9345  C CZ3   . TRP C 1 153 ? -37.770 -1.911  -69.856  1.00 89.79  ? 153 TRP C CZ3   1 
ATOM   9346  C CH2   . TRP C 1 153 ? -36.542 -2.016  -70.500  1.00 101.06 ? 153 TRP C CH2   1 
ATOM   9347  N N     . GLY C 1 154 ? -35.028 -2.325  -63.585  1.00 57.40  ? 154 GLY C N     1 
ATOM   9348  C CA    . GLY C 1 154 ? -33.871 -2.671  -62.767  1.00 56.68  ? 154 GLY C CA    1 
ATOM   9349  C C     . GLY C 1 154 ? -34.027 -2.271  -61.297  1.00 51.26  ? 154 GLY C C     1 
ATOM   9350  O O     . GLY C 1 154 ? -35.009 -1.637  -60.912  1.00 48.50  ? 154 GLY C O     1 
ATOM   9351  N N     . SER C 1 155 ? -33.071 -2.730  -60.480  1.00 50.86  ? 155 SER C N     1 
ATOM   9352  C CA    . SER C 1 155 ? -33.027 -2.491  -59.039  1.00 49.54  ? 155 SER C CA    1 
ATOM   9353  C C     . SER C 1 155 ? -32.276 -1.204  -58.706  1.00 48.04  ? 155 SER C C     1 
ATOM   9354  O O     . SER C 1 155 ? -31.079 -1.052  -58.998  1.00 46.21  ? 155 SER C O     1 
ATOM   9355  C CB    . SER C 1 155 ? -32.348 -3.619  -58.331  1.00 48.15  ? 155 SER C CB    1 
ATOM   9356  O OG    . SER C 1 155 ? -32.144 -3.254  -56.979  1.00 54.58  ? 155 SER C OG    1 
ATOM   9357  N N     . VAL C 1 156 ? -32.966 -0.302  -58.029  1.00 41.46  ? 156 VAL C N     1 
ATOM   9358  C CA    . VAL C 1 156 ? -32.281 0.828   -57.438  1.00 42.61  ? 156 VAL C CA    1 
ATOM   9359  C C     . VAL C 1 156 ? -30.967 0.356   -56.800  1.00 45.65  ? 156 VAL C C     1 
ATOM   9360  O O     . VAL C 1 156 ? -29.914 0.905   -57.099  1.00 45.34  ? 156 VAL C O     1 
ATOM   9361  C CB    . VAL C 1 156 ? -33.192 1.509   -56.416  1.00 44.02  ? 156 VAL C CB    1 
ATOM   9362  C CG1   . VAL C 1 156 ? -32.650 2.866   -56.028  1.00 53.99  ? 156 VAL C CG1   1 
ATOM   9363  C CG2   . VAL C 1 156 ? -34.603 1.655   -56.952  1.00 47.92  ? 156 VAL C CG2   1 
ATOM   9364  N N     . VAL C 1 157 ? -31.014 -0.696  -55.955  1.00 41.57  ? 157 VAL C N     1 
ATOM   9365  C CA    . VAL C 1 157 ? -29.849 -1.137  -55.210  1.00 37.62  ? 157 VAL C CA    1 
ATOM   9366  C C     . VAL C 1 157 ? -28.824 -1.790  -56.135  1.00 41.74  ? 157 VAL C C     1 
ATOM   9367  O O     . VAL C 1 157 ? -27.680 -1.343  -56.212  1.00 46.84  ? 157 VAL C O     1 
ATOM   9368  C CB    . VAL C 1 157 ? -30.224 -2.091  -54.062  1.00 38.29  ? 157 VAL C CB    1 
ATOM   9369  C CG1   . VAL C 1 157 ? -29.007 -2.787  -53.509  1.00 38.64  ? 157 VAL C CG1   1 
ATOM   9370  C CG2   . VAL C 1 157 ? -30.939 -1.393  -52.925  1.00 40.39  ? 157 VAL C CG2   1 
ATOM   9371  N N     . GLY C 1 158 ? -29.224 -2.878  -56.802  1.00 42.45  ? 158 GLY C N     1 
ATOM   9372  C CA    . GLY C 1 158 ? -28.329 -3.652  -57.648  1.00 39.79  ? 158 GLY C CA    1 
ATOM   9373  C C     . GLY C 1 158 ? -27.547 -2.763  -58.614  1.00 41.25  ? 158 GLY C C     1 
ATOM   9374  O O     . GLY C 1 158 ? -26.334 -2.873  -58.755  1.00 41.29  ? 158 GLY C O     1 
ATOM   9375  N N     . ASN C 1 159 ? -28.256 -1.850  -59.263  1.00 44.72  ? 159 ASN C N     1 
ATOM   9376  C CA    . ASN C 1 159 ? -27.648 -1.001  -60.269  1.00 45.71  ? 159 ASN C CA    1 
ATOM   9377  C C     . ASN C 1 159 ? -26.640 -0.054  -59.624  1.00 43.59  ? 159 ASN C C     1 
ATOM   9378  O O     . ASN C 1 159 ? -25.519 0.111   -60.125  1.00 41.80  ? 159 ASN C O     1 
ATOM   9379  C CB    . ASN C 1 159 ? -28.736 -0.279  -61.058  1.00 50.14  ? 159 ASN C CB    1 
ATOM   9380  C CG    . ASN C 1 159 ? -28.154 0.841   -61.865  1.00 52.95  ? 159 ASN C CG    1 
ATOM   9381  O OD1   . ASN C 1 159 ? -27.748 1.840   -61.276  1.00 58.76  ? 159 ASN C OD1   1 
ATOM   9382  N ND2   . ASN C 1 159 ? -28.099 0.668   -63.176  1.00 46.97  ? 159 ASN C ND2   1 
ATOM   9383  N N     . ALA C 1 160 ? -27.026 0.550   -58.491  1.00 44.08  ? 160 ALA C N     1 
ATOM   9384  C CA    . ALA C 1 160 ? -26.099 1.374   -57.723  1.00 42.85  ? 160 ALA C CA    1 
ATOM   9385  C C     . ALA C 1 160 ? -24.852 0.579   -57.339  1.00 41.41  ? 160 ALA C C     1 
ATOM   9386  O O     . ALA C 1 160 ? -23.743 1.059   -57.503  1.00 41.53  ? 160 ALA C O     1 
ATOM   9387  C CB    . ALA C 1 160 ? -26.789 1.921   -56.505  1.00 49.41  ? 160 ALA C CB    1 
ATOM   9388  N N     . LEU C 1 161 ? -25.031 -0.653  -56.836  1.00 41.28  ? 161 LEU C N     1 
ATOM   9389  C CA    . LEU C 1 161 ? -23.902 -1.470  -56.446  1.00 39.31  ? 161 LEU C CA    1 
ATOM   9390  C C     . LEU C 1 161 ? -23.000 -1.834  -57.628  1.00 42.33  ? 161 LEU C C     1 
ATOM   9391  O O     . LEU C 1 161 ? -21.849 -2.209  -57.402  1.00 44.19  ? 161 LEU C O     1 
ATOM   9392  C CB    . LEU C 1 161 ? -24.427 -2.741  -55.789  1.00 39.23  ? 161 LEU C CB    1 
ATOM   9393  C CG    . LEU C 1 161 ? -25.097 -2.595  -54.431  1.00 45.70  ? 161 LEU C CG    1 
ATOM   9394  C CD1   . LEU C 1 161 ? -25.160 -3.948  -53.720  1.00 46.20  ? 161 LEU C CD1   1 
ATOM   9395  C CD2   . LEU C 1 161 ? -24.390 -1.575  -53.565  1.00 46.78  ? 161 LEU C CD2   1 
ATOM   9396  N N     . ASP C 1 162 ? -23.518 -1.833  -58.868  1.00 47.05  ? 162 ASP C N     1 
ATOM   9397  C CA    . ASP C 1 162 ? -22.707 -2.207  -60.029  1.00 56.61  ? 162 ASP C CA    1 
ATOM   9398  C C     . ASP C 1 162 ? -22.106 -0.968  -60.700  1.00 48.52  ? 162 ASP C C     1 
ATOM   9399  O O     . ASP C 1 162 ? -21.710 -1.051  -61.857  1.00 53.25  ? 162 ASP C O     1 
ATOM   9400  C CB    . ASP C 1 162 ? -23.499 -3.055  -61.045  1.00 63.71  ? 162 ASP C CB    1 
ATOM   9401  C CG    . ASP C 1 162 ? -22.664 -3.986  -61.924  1.00 68.71  ? 162 ASP C CG    1 
ATOM   9402  O OD1   . ASP C 1 162 ? -21.776 -4.706  -61.374  1.00 66.79  ? 162 ASP C OD1   1 
ATOM   9403  O OD2   . ASP C 1 162 ? -22.936 -4.031  -63.141  1.00 68.62  ? 162 ASP C OD2   1 
ATOM   9404  N N     . HIS C 1 163 ? -22.032 0.134   -59.941  1.00 42.42  ? 163 HIS C N     1 
ATOM   9405  C CA    . HIS C 1 163 ? -21.476 1.428   -60.314  1.00 40.29  ? 163 HIS C CA    1 
ATOM   9406  C C     . HIS C 1 163 ? -22.236 2.015   -61.478  1.00 44.38  ? 163 HIS C C     1 
ATOM   9407  O O     . HIS C 1 163 ? -21.635 2.632   -62.341  1.00 48.74  ? 163 HIS C O     1 
ATOM   9408  C CB    . HIS C 1 163 ? -19.972 1.375   -60.572  1.00 43.23  ? 163 HIS C CB    1 
ATOM   9409  C CG    . HIS C 1 163 ? -19.195 1.042   -59.351  1.00 42.30  ? 163 HIS C CG    1 
ATOM   9410  N ND1   . HIS C 1 163 ? -17.982 0.405   -59.390  1.00 45.42  ? 163 HIS C ND1   1 
ATOM   9411  C CD2   . HIS C 1 163 ? -19.507 1.161   -58.066  1.00 43.09  ? 163 HIS C CD2   1 
ATOM   9412  C CE1   . HIS C 1 163 ? -17.571 0.187   -58.152  1.00 46.43  ? 163 HIS C CE1   1 
ATOM   9413  N NE2   . HIS C 1 163 ? -18.471 0.659   -57.332  1.00 42.10  ? 163 HIS C NE2   1 
ATOM   9414  N N     . GLY C 1 164 ? -23.566 1.880   -61.423  1.00 53.90  ? 164 GLY C N     1 
ATOM   9415  C CA    . GLY C 1 164 ? -24.439 2.335   -62.489  1.00 50.66  ? 164 GLY C CA    1 
ATOM   9416  C C     . GLY C 1 164 ? -24.511 3.856   -62.594  1.00 46.21  ? 164 GLY C C     1 
ATOM   9417  O O     . GLY C 1 164 ? -24.274 4.540   -61.610  1.00 44.29  ? 164 GLY C O     1 
ATOM   9418  N N     . ILE C 1 165 ? -24.906 4.342   -63.783  1.00 50.21  ? 165 ILE C N     1 
ATOM   9419  C CA    . ILE C 1 165 ? -25.089 5.758   -64.072  1.00 53.58  ? 165 ILE C CA    1 
ATOM   9420  C C     . ILE C 1 165 ? -26.506 6.022   -64.572  1.00 52.51  ? 165 ILE C C     1 
ATOM   9421  O O     . ILE C 1 165 ? -27.218 5.092   -64.963  1.00 58.77  ? 165 ILE C O     1 
ATOM   9422  C CB    . ILE C 1 165 ? -24.046 6.251   -65.095  1.00 58.35  ? 165 ILE C CB    1 
ATOM   9423  C CG1   . ILE C 1 165 ? -24.228 5.575   -66.463  1.00 72.20  ? 165 ILE C CG1   1 
ATOM   9424  C CG2   . ILE C 1 165 ? -22.647 6.061   -64.515  1.00 59.68  ? 165 ILE C CG2   1 
ATOM   9425  C CD1   . ILE C 1 165 ? -23.409 6.177   -67.596  1.00 78.16  ? 165 ILE C CD1   1 
ATOM   9426  N N     . GLY C 1 166 ? -26.868 7.315   -64.595  1.00 47.98  ? 166 GLY C N     1 
ATOM   9427  C CA    . GLY C 1 166 ? -28.113 7.808   -65.178  1.00 42.70  ? 166 GLY C CA    1 
ATOM   9428  C C     . GLY C 1 166 ? -27.926 9.238   -65.674  1.00 41.58  ? 166 GLY C C     1 
ATOM   9429  O O     . GLY C 1 166 ? -26.781 9.642   -65.887  1.00 38.09  ? 166 GLY C O     1 
ATOM   9430  N N     . TYR C 1 167 ? -29.019 10.015  -65.814  1.00 42.63  ? 167 TYR C N     1 
ATOM   9431  C CA    . TYR C 1 167 ? -28.980 11.150  -66.737  1.00 48.59  ? 167 TYR C CA    1 
ATOM   9432  C C     . TYR C 1 167 ? -29.452 12.461  -66.096  1.00 47.74  ? 167 TYR C C     1 
ATOM   9433  O O     . TYR C 1 167 ? -29.639 13.450  -66.812  1.00 53.55  ? 167 TYR C O     1 
ATOM   9434  C CB    . TYR C 1 167 ? -29.715 10.764  -68.036  1.00 49.65  ? 167 TYR C CB    1 
ATOM   9435  C CG    . TYR C 1 167 ? -29.110 9.549   -68.711  1.00 61.34  ? 167 TYR C CG    1 
ATOM   9436  C CD1   . TYR C 1 167 ? -28.057 9.668   -69.608  1.00 60.78  ? 167 TYR C CD1   1 
ATOM   9437  C CD2   . TYR C 1 167 ? -29.504 8.260   -68.360  1.00 61.00  ? 167 TYR C CD2   1 
ATOM   9438  C CE1   . TYR C 1 167 ? -27.445 8.554   -70.156  1.00 63.71  ? 167 TYR C CE1   1 
ATOM   9439  C CE2   . TYR C 1 167 ? -28.898 7.136   -68.901  1.00 57.70  ? 167 TYR C CE2   1 
ATOM   9440  C CZ    . TYR C 1 167 ? -27.858 7.285   -69.794  1.00 62.40  ? 167 TYR C CZ    1 
ATOM   9441  O OH    . TYR C 1 167 ? -27.269 6.180   -70.347  1.00 64.44  ? 167 TYR C OH    1 
ATOM   9442  N N     . THR C 1 168 ? -29.580 12.503  -64.761  1.00 45.29  ? 168 THR C N     1 
ATOM   9443  C CA    . THR C 1 168 ? -29.831 13.751  -64.033  1.00 48.71  ? 168 THR C CA    1 
ATOM   9444  C C     . THR C 1 168 ? -28.572 14.232  -63.297  1.00 46.34  ? 168 THR C C     1 
ATOM   9445  O O     . THR C 1 168 ? -27.538 13.575  -63.279  1.00 45.48  ? 168 THR C O     1 
ATOM   9446  C CB    . THR C 1 168 ? -30.986 13.587  -63.038  1.00 49.41  ? 168 THR C CB    1 
ATOM   9447  O OG1   . THR C 1 168 ? -30.431 13.079  -61.816  1.00 44.41  ? 168 THR C OG1   1 
ATOM   9448  C CG2   . THR C 1 168 ? -32.095 12.705  -63.583  1.00 49.77  ? 168 THR C CG2   1 
ATOM   9449  N N     . PRO C 1 169 ? -28.587 15.396  -62.614  1.00 45.25  ? 169 PRO C N     1 
ATOM   9450  C CA    . PRO C 1 169 ? -27.458 15.761  -61.749  1.00 43.26  ? 169 PRO C CA    1 
ATOM   9451  C C     . PRO C 1 169 ? -27.115 14.702  -60.694  1.00 38.56  ? 169 PRO C C     1 
ATOM   9452  O O     . PRO C 1 169 ? -25.958 14.603  -60.315  1.00 37.69  ? 169 PRO C O     1 
ATOM   9453  C CB    . PRO C 1 169 ? -27.912 17.088  -61.121  1.00 43.61  ? 169 PRO C CB    1 
ATOM   9454  C CG    . PRO C 1 169 ? -28.883 17.640  -62.151  1.00 43.98  ? 169 PRO C CG    1 
ATOM   9455  C CD    . PRO C 1 169 ? -29.648 16.415  -62.615  1.00 42.58  ? 169 PRO C CD    1 
ATOM   9456  N N     . TYR C 1 170 ? -28.078 13.858  -60.296  1.00 38.62  ? 170 TYR C N     1 
ATOM   9457  C CA    . TYR C 1 170 ? -27.831 12.719  -59.415  1.00 40.83  ? 170 TYR C CA    1 
ATOM   9458  C C     . TYR C 1 170 ? -27.472 11.449  -60.188  1.00 39.92  ? 170 TYR C C     1 
ATOM   9459  O O     . TYR C 1 170 ? -27.746 10.356  -59.715  1.00 40.19  ? 170 TYR C O     1 
ATOM   9460  C CB    . TYR C 1 170 ? -29.051 12.445  -58.517  1.00 46.33  ? 170 TYR C CB    1 
ATOM   9461  C CG    . TYR C 1 170 ? -29.203 13.369  -57.327  1.00 45.18  ? 170 TYR C CG    1 
ATOM   9462  C CD1   . TYR C 1 170 ? -28.996 14.728  -57.453  1.00 41.80  ? 170 TYR C CD1   1 
ATOM   9463  C CD2   . TYR C 1 170 ? -29.536 12.885  -56.068  1.00 46.33  ? 170 TYR C CD2   1 
ATOM   9464  C CE1   . TYR C 1 170 ? -29.122 15.583  -56.376  1.00 45.51  ? 170 TYR C CE1   1 
ATOM   9465  C CE2   . TYR C 1 170 ? -29.674 13.732  -54.979  1.00 42.42  ? 170 TYR C CE2   1 
ATOM   9466  C CZ    . TYR C 1 170 ? -29.458 15.088  -55.129  1.00 42.13  ? 170 TYR C CZ    1 
ATOM   9467  O OH    . TYR C 1 170 ? -29.596 15.994  -54.094  1.00 41.20  ? 170 TYR C OH    1 
ATOM   9468  N N     . GLY C 1 171 ? -26.807 11.579  -61.348  1.00 45.91  ? 171 GLY C N     1 
ATOM   9469  C CA    . GLY C 1 171 ? -26.569 10.459  -62.258  1.00 39.76  ? 171 GLY C CA    1 
ATOM   9470  C C     . GLY C 1 171 ? -25.526 9.442   -61.781  1.00 44.24  ? 171 GLY C C     1 
ATOM   9471  O O     . GLY C 1 171 ? -25.533 8.317   -62.266  1.00 41.39  ? 171 GLY C O     1 
ATOM   9472  N N     . ASP C 1 172 ? -24.632 9.796   -60.836  1.00 49.27  ? 172 ASP C N     1 
ATOM   9473  C CA    . ASP C 1 172 ? -23.682 8.814   -60.308  1.00 45.25  ? 172 ASP C CA    1 
ATOM   9474  C C     . ASP C 1 172 ? -24.312 8.081   -59.113  1.00 41.73  ? 172 ASP C C     1 
ATOM   9475  O O     . ASP C 1 172 ? -24.368 8.605   -58.011  1.00 44.83  ? 172 ASP C O     1 
ATOM   9476  C CB    . ASP C 1 172 ? -22.338 9.471   -59.986  1.00 40.79  ? 172 ASP C CB    1 
ATOM   9477  C CG    . ASP C 1 172 ? -21.298 8.528   -59.401  1.00 44.65  ? 172 ASP C CG    1 
ATOM   9478  O OD1   . ASP C 1 172 ? -21.659 7.337   -59.058  1.00 44.71  ? 172 ASP C OD1   1 
ATOM   9479  O OD2   . ASP C 1 172 ? -20.126 8.976   -59.290  1.00 42.71  ? 172 ASP C OD2   1 
ATOM   9480  N N     . HIS C 1 173 ? -24.793 6.856   -59.329  1.00 41.00  ? 173 HIS C N     1 
ATOM   9481  C CA    . HIS C 1 173 ? -25.779 6.274   -58.439  1.00 42.70  ? 173 HIS C CA    1 
ATOM   9482  C C     . HIS C 1 173 ? -25.123 5.865   -57.130  1.00 45.52  ? 173 HIS C C     1 
ATOM   9483  O O     . HIS C 1 173 ? -25.702 6.096   -56.078  1.00 42.30  ? 173 HIS C O     1 
ATOM   9484  C CB    . HIS C 1 173 ? -26.503 5.095   -59.092  1.00 46.64  ? 173 HIS C CB    1 
ATOM   9485  C CG    . HIS C 1 173 ? -27.399 5.490   -60.220  1.00 52.10  ? 173 HIS C CG    1 
ATOM   9486  N ND1   . HIS C 1 173 ? -28.012 4.564   -61.026  1.00 54.18  ? 173 HIS C ND1   1 
ATOM   9487  C CD2   . HIS C 1 173 ? -27.772 6.683   -60.707  1.00 62.87  ? 173 HIS C CD2   1 
ATOM   9488  C CE1   . HIS C 1 173 ? -28.763 5.183   -61.929  1.00 58.55  ? 173 HIS C CE1   1 
ATOM   9489  N NE2   . HIS C 1 173 ? -28.625 6.468   -61.770  1.00 57.63  ? 173 HIS C NE2   1 
ATOM   9490  N N     . PHE C 1 174 ? -23.929 5.255   -57.193  1.00 49.19  ? 174 PHE C N     1 
ATOM   9491  C CA    . PHE C 1 174 ? -23.291 4.786   -55.974  1.00 48.87  ? 174 PHE C CA    1 
ATOM   9492  C C     . PHE C 1 174 ? -22.748 5.959   -55.166  1.00 46.13  ? 174 PHE C C     1 
ATOM   9493  O O     . PHE C 1 174 ? -22.644 5.881   -53.950  1.00 51.97  ? 174 PHE C O     1 
ATOM   9494  C CB    . PHE C 1 174 ? -22.189 3.758   -56.216  1.00 46.23  ? 174 PHE C CB    1 
ATOM   9495  C CG    . PHE C 1 174 ? -21.708 3.149   -54.921  1.00 47.05  ? 174 PHE C CG    1 
ATOM   9496  C CD1   . PHE C 1 174 ? -22.553 2.361   -54.157  1.00 44.28  ? 174 PHE C CD1   1 
ATOM   9497  C CD2   . PHE C 1 174 ? -20.442 3.428   -54.425  1.00 51.27  ? 174 PHE C CD2   1 
ATOM   9498  C CE1   . PHE C 1 174 ? -22.141 1.849   -52.937  1.00 46.04  ? 174 PHE C CE1   1 
ATOM   9499  C CE2   . PHE C 1 174 ? -20.025 2.906   -53.210  1.00 52.43  ? 174 PHE C CE2   1 
ATOM   9500  C CZ    . PHE C 1 174 ? -20.874 2.108   -52.471  1.00 50.92  ? 174 PHE C CZ    1 
ATOM   9501  N N     . ALA C 1 175 ? -22.455 7.065   -55.838  1.00 42.13  ? 175 ALA C N     1 
ATOM   9502  C CA    . ALA C 1 175 ? -22.050 8.277   -55.151  1.00 41.13  ? 175 ALA C CA    1 
ATOM   9503  C C     . ALA C 1 175 ? -23.145 8.773   -54.199  1.00 42.67  ? 175 ALA C C     1 
ATOM   9504  O O     . ALA C 1 175 ? -22.845 9.378   -53.163  1.00 46.52  ? 175 ALA C O     1 
ATOM   9505  C CB    . ALA C 1 175 ? -21.698 9.325   -56.190  1.00 40.59  ? 175 ALA C CB    1 
ATOM   9506  N N     . MET C 1 176 ? -24.407 8.565   -54.593  1.00 40.95  ? 176 MET C N     1 
ATOM   9507  C CA    . MET C 1 176 ? -25.564 9.072   -53.883  1.00 39.72  ? 176 MET C CA    1 
ATOM   9508  C C     . MET C 1 176 ? -26.027 8.051   -52.840  1.00 39.22  ? 176 MET C C     1 
ATOM   9509  O O     . MET C 1 176 ? -26.974 8.309   -52.094  1.00 40.00  ? 176 MET C O     1 
ATOM   9510  C CB    . MET C 1 176 ? -26.724 9.349   -54.845  1.00 42.82  ? 176 MET C CB    1 
ATOM   9511  C CG    . MET C 1 176 ? -26.414 10.418  -55.922  1.00 44.54  ? 176 MET C CG    1 
ATOM   9512  S SD    . MET C 1 176 ? -26.096 12.077  -55.274  1.00 47.58  ? 176 MET C SD    1 
ATOM   9513  C CE    . MET C 1 176 ? -24.322 12.131  -55.501  1.00 54.08  ? 176 MET C CE    1 
ATOM   9514  N N     . GLN C 1 177 ? -25.372 6.891   -52.769  1.00 36.64  ? 177 GLN C N     1 
ATOM   9515  C CA    . GLN C 1 177 ? -25.755 5.913   -51.761  1.00 42.55  ? 177 GLN C CA    1 
ATOM   9516  C C     . GLN C 1 177 ? -25.352 6.419   -50.380  1.00 40.35  ? 177 GLN C C     1 
ATOM   9517  O O     . GLN C 1 177 ? -24.413 7.182   -50.258  1.00 41.95  ? 177 GLN C O     1 
ATOM   9518  C CB    . GLN C 1 177 ? -25.111 4.552   -52.013  1.00 41.44  ? 177 GLN C CB    1 
ATOM   9519  C CG    . GLN C 1 177 ? -25.336 3.535   -50.898  1.00 43.41  ? 177 GLN C CG    1 
ATOM   9520  C CD    . GLN C 1 177 ? -24.197 3.397   -49.914  1.00 48.42  ? 177 GLN C CD    1 
ATOM   9521  O OE1   . GLN C 1 177 ? -23.048 3.730   -50.202  1.00 54.73  ? 177 GLN C OE1   1 
ATOM   9522  N NE2   . GLN C 1 177 ? -24.495 2.804   -48.766  1.00 52.01  ? 177 GLN C NE2   1 
ATOM   9523  N N     . CYS C 1 178 ? -26.075 5.985   -49.347  1.00 39.56  ? 178 CYS C N     1 
ATOM   9524  C CA    . CYS C 1 178 ? -25.809 6.442   -48.002  1.00 35.89  ? 178 CYS C CA    1 
ATOM   9525  C C     . CYS C 1 178 ? -26.475 5.519   -46.987  1.00 32.91  ? 178 CYS C C     1 
ATOM   9526  O O     . CYS C 1 178 ? -27.701 5.500   -46.829  1.00 34.83  ? 178 CYS C O     1 
ATOM   9527  C CB    . CYS C 1 178 ? -26.277 7.884   -47.866  1.00 38.86  ? 178 CYS C CB    1 
ATOM   9528  S SG    . CYS C 1 178 ? -25.936 8.558   -46.227  1.00 41.10  ? 178 CYS C SG    1 
ATOM   9529  N N     . GLY C 1 179 ? -25.646 4.754   -46.289  1.00 34.78  ? 179 GLY C N     1 
ATOM   9530  C CA    . GLY C 1 179 ? -26.139 3.699   -45.418  1.00 40.94  ? 179 GLY C CA    1 
ATOM   9531  C C     . GLY C 1 179 ? -26.522 2.427   -46.188  1.00 39.22  ? 179 GLY C C     1 
ATOM   9532  O O     . GLY C 1 179 ? -27.203 2.494   -47.215  1.00 38.48  ? 179 GLY C O     1 
ATOM   9533  N N     . MET C 1 180 ? -26.074 1.273   -45.676  1.00 36.97  ? 180 MET C N     1 
ATOM   9534  C CA    . MET C 1 180 ? -26.548 -0.026  -46.137  1.00 36.81  ? 180 MET C CA    1 
ATOM   9535  C C     . MET C 1 180 ? -26.535 -0.994  -44.961  1.00 40.41  ? 180 MET C C     1 
ATOM   9536  O O     . MET C 1 180 ? -25.877 -0.733  -43.950  1.00 44.60  ? 180 MET C O     1 
ATOM   9537  C CB    . MET C 1 180 ? -25.717 -0.605  -47.281  1.00 38.13  ? 180 MET C CB    1 
ATOM   9538  C CG    . MET C 1 180 ? -24.246 -0.738  -46.966  1.00 42.66  ? 180 MET C CG    1 
ATOM   9539  S SD    . MET C 1 180 ? -23.289 -1.455  -48.328  1.00 48.46  ? 180 MET C SD    1 
ATOM   9540  C CE    . MET C 1 180 ? -23.533 -0.238  -49.616  1.00 51.14  ? 180 MET C CE    1 
ATOM   9541  N N     . GLU C 1 181 ? -27.375 -2.035  -45.065  1.00 46.61  ? 181 GLU C N     1 
ATOM   9542  C CA    . GLU C 1 181 ? -27.286 -3.229  -44.232  1.00 40.80  ? 181 GLU C CA    1 
ATOM   9543  C C     . GLU C 1 181 ? -26.754 -4.351  -45.100  1.00 37.21  ? 181 GLU C C     1 
ATOM   9544  O O     . GLU C 1 181 ? -27.166 -4.482  -46.252  1.00 36.49  ? 181 GLU C O     1 
ATOM   9545  C CB    . GLU C 1 181 ? -28.653 -3.612  -43.679  1.00 40.71  ? 181 GLU C CB    1 
ATOM   9546  C CG    . GLU C 1 181 ? -28.655 -4.801  -42.742  1.00 42.64  ? 181 GLU C CG    1 
ATOM   9547  C CD    . GLU C 1 181 ? -30.059 -5.163  -42.281  1.00 46.97  ? 181 GLU C CD    1 
ATOM   9548  O OE1   . GLU C 1 181 ? -30.332 -5.128  -41.061  1.00 62.34  ? 181 GLU C OE1   1 
ATOM   9549  O OE2   . GLU C 1 181 ? -30.895 -5.440  -43.139  1.00 48.83  ? 181 GLU C OE2   1 
ATOM   9550  N N     . VAL C 1 182 ? -25.858 -5.154  -44.516  1.00 42.11  ? 182 VAL C N     1 
ATOM   9551  C CA    . VAL C 1 182 ? -25.133 -6.188  -45.236  1.00 37.78  ? 182 VAL C CA    1 
ATOM   9552  C C     . VAL C 1 182 ? -25.153 -7.465  -44.410  1.00 35.68  ? 182 VAL C C     1 
ATOM   9553  O O     . VAL C 1 182 ? -24.883 -7.437  -43.214  1.00 36.47  ? 182 VAL C O     1 
ATOM   9554  C CB    . VAL C 1 182 ? -23.694 -5.719  -45.510  1.00 40.96  ? 182 VAL C CB    1 
ATOM   9555  C CG1   . VAL C 1 182 ? -22.974 -6.629  -46.487  1.00 38.93  ? 182 VAL C CG1   1 
ATOM   9556  C CG2   . VAL C 1 182 ? -23.695 -4.281  -46.012  1.00 44.26  ? 182 VAL C CG2   1 
ATOM   9557  N N     . VAL C 1 183 ? -25.484 -8.578  -45.067  1.00 39.77  ? 183 VAL C N     1 
ATOM   9558  C CA    . VAL C 1 183 ? -25.230 -9.909  -44.538  1.00 39.06  ? 183 VAL C CA    1 
ATOM   9559  C C     . VAL C 1 183 ? -23.847 -10.316 -45.023  1.00 39.84  ? 183 VAL C C     1 
ATOM   9560  O O     . VAL C 1 183 ? -23.616 -10.397 -46.229  1.00 45.59  ? 183 VAL C O     1 
ATOM   9561  C CB    . VAL C 1 183 ? -26.285 -10.930 -44.999  1.00 37.48  ? 183 VAL C CB    1 
ATOM   9562  C CG1   . VAL C 1 183 ? -25.927 -12.325 -44.533  1.00 42.62  ? 183 VAL C CG1   1 
ATOM   9563  C CG2   . VAL C 1 183 ? -27.687 -10.574 -44.557  1.00 39.24  ? 183 VAL C CG2   1 
ATOM   9564  N N     . LEU C 1 184 ? -22.922 -10.530 -44.092  1.00 40.35  ? 184 LEU C N     1 
ATOM   9565  C CA    . LEU C 1 184 ? -21.555 -10.887 -44.447  1.00 41.87  ? 184 LEU C CA    1 
ATOM   9566  C C     . LEU C 1 184 ? -21.529 -12.372 -44.788  1.00 45.05  ? 184 LEU C C     1 
ATOM   9567  O O     . LEU C 1 184 ? -22.486 -13.086 -44.497  1.00 44.91  ? 184 LEU C O     1 
ATOM   9568  C CB    . LEU C 1 184 ? -20.595 -10.554 -43.297  1.00 39.40  ? 184 LEU C CB    1 
ATOM   9569  C CG    . LEU C 1 184 ? -20.496 -9.082  -42.884  1.00 39.51  ? 184 LEU C CG    1 
ATOM   9570  C CD1   . LEU C 1 184 ? -19.696 -8.914  -41.595  1.00 36.47  ? 184 LEU C CD1   1 
ATOM   9571  C CD2   . LEU C 1 184 ? -19.889 -8.230  -43.983  1.00 40.17  ? 184 LEU C CD2   1 
ATOM   9572  N N     . PRO C 1 185 ? -20.446 -12.874 -45.420  1.00 49.70  ? 185 PRO C N     1 
ATOM   9573  C CA    . PRO C 1 185 ? -20.358 -14.273 -45.835  1.00 52.46  ? 185 PRO C CA    1 
ATOM   9574  C C     . PRO C 1 185 ? -20.317 -15.318 -44.716  1.00 50.69  ? 185 PRO C C     1 
ATOM   9575  O O     . PRO C 1 185 ? -20.483 -16.503 -44.984  1.00 53.57  ? 185 PRO C O     1 
ATOM   9576  C CB    . PRO C 1 185 ? -19.048 -14.307 -46.638  1.00 48.02  ? 185 PRO C CB    1 
ATOM   9577  C CG    . PRO C 1 185 ? -18.840 -12.896 -47.068  1.00 48.98  ? 185 PRO C CG    1 
ATOM   9578  C CD    . PRO C 1 185 ? -19.280 -12.102 -45.864  1.00 52.66  ? 185 PRO C CD    1 
ATOM   9579  N N     . ASN C 1 186 ? -20.113 -14.887 -43.469  1.00 49.43  ? 186 ASN C N     1 
ATOM   9580  C CA    . ASN C 1 186 ? -20.285 -15.755 -42.299  1.00 47.73  ? 186 ASN C CA    1 
ATOM   9581  C C     . ASN C 1 186 ? -21.742 -15.751 -41.792  1.00 49.67  ? 186 ASN C C     1 
ATOM   9582  O O     . ASN C 1 186 ? -22.061 -16.455 -40.832  1.00 47.85  ? 186 ASN C O     1 
ATOM   9583  C CB    . ASN C 1 186 ? -19.298 -15.366 -41.191  1.00 41.53  ? 186 ASN C CB    1 
ATOM   9584  C CG    . ASN C 1 186 ? -19.477 -13.951 -40.655  1.00 50.48  ? 186 ASN C CG    1 
ATOM   9585  O OD1   . ASN C 1 186 ? -20.426 -13.238 -41.005  1.00 50.13  ? 186 ASN C OD1   1 
ATOM   9586  N ND2   . ASN C 1 186 ? -18.604 -13.544 -39.747  1.00 48.69  ? 186 ASN C ND2   1 
ATOM   9587  N N     . GLY C 1 187 ? -22.626 -14.942 -42.408  1.00 43.54  ? 187 GLY C N     1 
ATOM   9588  C CA    . GLY C 1 187 ? -24.026 -14.867 -42.015  1.00 45.82  ? 187 GLY C CA    1 
ATOM   9589  C C     . GLY C 1 187 ? -24.358 -13.851 -40.911  1.00 48.27  ? 187 GLY C C     1 
ATOM   9590  O O     . GLY C 1 187 ? -25.518 -13.793 -40.494  1.00 47.45  ? 187 GLY C O     1 
ATOM   9591  N N     . GLU C 1 188 ? -23.383 -13.040 -40.462  1.00 43.79  ? 188 GLU C N     1 
ATOM   9592  C CA    . GLU C 1 188 ? -23.637 -11.969 -39.498  1.00 45.66  ? 188 GLU C CA    1 
ATOM   9593  C C     . GLU C 1 188 ? -24.148 -10.737 -40.236  1.00 47.00  ? 188 GLU C C     1 
ATOM   9594  O O     . GLU C 1 188 ? -23.719 -10.503 -41.355  1.00 47.03  ? 188 GLU C O     1 
ATOM   9595  C CB    . GLU C 1 188 ? -22.360 -11.455 -38.825  1.00 41.90  ? 188 GLU C CB    1 
ATOM   9596  C CG    . GLU C 1 188 ? -21.568 -12.505 -38.108  1.00 41.33  ? 188 GLU C CG    1 
ATOM   9597  C CD    . GLU C 1 188 ? -22.344 -13.022 -36.922  1.00 50.73  ? 188 GLU C CD    1 
ATOM   9598  O OE1   . GLU C 1 188 ? -22.376 -12.298 -35.912  1.00 54.88  ? 188 GLU C OE1   1 
ATOM   9599  O OE2   . GLU C 1 188 ? -22.962 -14.110 -37.042  1.00 57.42  ? 188 GLU C OE2   1 
ATOM   9600  N N     . VAL C 1 189 ? -24.993 -9.920  -39.588  1.00 45.11  ? 189 VAL C N     1 
ATOM   9601  C CA    . VAL C 1 189 ? -25.520 -8.716  -40.220  1.00 40.30  ? 189 VAL C CA    1 
ATOM   9602  C C     . VAL C 1 189 ? -24.847 -7.485  -39.607  1.00 43.12  ? 189 VAL C C     1 
ATOM   9603  O O     . VAL C 1 189 ? -24.521 -7.511  -38.418  1.00 38.29  ? 189 VAL C O     1 
ATOM   9604  C CB    . VAL C 1 189 ? -27.053 -8.664  -40.116  1.00 38.26  ? 189 VAL C CB    1 
ATOM   9605  C CG1   . VAL C 1 189 ? -27.531 -8.751  -38.682  1.00 41.55  ? 189 VAL C CG1   1 
ATOM   9606  C CG2   . VAL C 1 189 ? -27.650 -7.444  -40.809  1.00 37.68  ? 189 VAL C CG2   1 
ATOM   9607  N N     . VAL C 1 190 ? -24.610 -6.457  -40.454  1.00 40.77  ? 190 VAL C N     1 
ATOM   9608  C CA    . VAL C 1 190 ? -24.008 -5.188  -40.065  1.00 41.98  ? 190 VAL C CA    1 
ATOM   9609  C C     . VAL C 1 190 ? -24.746 -4.054  -40.776  1.00 40.83  ? 190 VAL C C     1 
ATOM   9610  O O     . VAL C 1 190 ? -25.217 -4.207  -41.902  1.00 42.50  ? 190 VAL C O     1 
ATOM   9611  C CB    . VAL C 1 190 ? -22.502 -5.064  -40.400  1.00 40.08  ? 190 VAL C CB    1 
ATOM   9612  C CG1   . VAL C 1 190 ? -21.643 -6.014  -39.626  1.00 42.32  ? 190 VAL C CG1   1 
ATOM   9613  C CG2   . VAL C 1 190 ? -22.241 -5.259  -41.871  1.00 47.16  ? 190 VAL C CG2   1 
ATOM   9614  N N     . ARG C 1 191 ? -24.723 -2.887  -40.130  1.00 35.91  ? 191 ARG C N     1 
ATOM   9615  C CA    . ARG C 1 191 ? -25.144 -1.647  -40.723  1.00 35.48  ? 191 ARG C CA    1 
ATOM   9616  C C     . ARG C 1 191 ? -23.951 -0.702  -40.726  1.00 36.42  ? 191 ARG C C     1 
ATOM   9617  O O     . ARG C 1 191 ? -23.187 -0.623  -39.768  1.00 38.19  ? 191 ARG C O     1 
ATOM   9618  C CB    . ARG C 1 191 ? -26.318 -1.076  -39.937  1.00 38.48  ? 191 ARG C CB    1 
ATOM   9619  C CG    . ARG C 1 191 ? -27.522 -1.998  -39.866  1.00 40.99  ? 191 ARG C CG    1 
ATOM   9620  C CD    . ARG C 1 191 ? -28.816 -1.382  -39.342  1.00 40.03  ? 191 ARG C CD    1 
ATOM   9621  N NE    . ARG C 1 191 ? -29.846 -2.404  -39.468  1.00 43.78  ? 191 ARG C NE    1 
ATOM   9622  C CZ    . ARG C 1 191 ? -31.136 -2.221  -39.226  1.00 45.28  ? 191 ARG C CZ    1 
ATOM   9623  N NH1   . ARG C 1 191 ? -31.527 -1.193  -38.506  1.00 45.29  ? 191 ARG C NH1   1 
ATOM   9624  N NH2   . ARG C 1 191 ? -32.034 -3.069  -39.698  1.00 42.66  ? 191 ARG C NH2   1 
ATOM   9625  N N     . THR C 1 192 ? -23.796 -0.016  -41.847  1.00 37.14  ? 192 THR C N     1 
ATOM   9626  C CA    . THR C 1 192 ? -22.694 0.902   -42.042  1.00 38.99  ? 192 THR C CA    1 
ATOM   9627  C C     . THR C 1 192 ? -23.097 2.299   -41.615  1.00 35.83  ? 192 THR C C     1 
ATOM   9628  O O     . THR C 1 192 ? -24.289 2.579   -41.472  1.00 33.35  ? 192 THR C O     1 
ATOM   9629  C CB    . THR C 1 192 ? -22.290 0.975   -43.518  1.00 39.23  ? 192 THR C CB    1 
ATOM   9630  O OG1   . THR C 1 192 ? -23.399 1.544   -44.228  1.00 36.75  ? 192 THR C OG1   1 
ATOM   9631  C CG2   . THR C 1 192 ? -21.898 -0.387  -44.038  1.00 40.52  ? 192 THR C CG2   1 
ATOM   9632  N N     . GLY C 1 193 ? -22.081 3.166   -41.496  1.00 31.26  ? 193 GLY C N     1 
ATOM   9633  C CA    . GLY C 1 193 ? -22.327 4.570   -41.283  1.00 31.76  ? 193 GLY C CA    1 
ATOM   9634  C C     . GLY C 1 193 ? -23.067 4.764   -39.975  1.00 33.39  ? 193 GLY C C     1 
ATOM   9635  O O     . GLY C 1 193 ? -22.772 4.069   -39.003  1.00 28.78  ? 193 GLY C O     1 
ATOM   9636  N N     . MET C 1 194 ? -24.026 5.699   -39.967  1.00 36.89  ? 194 MET C N     1 
ATOM   9637  C CA    . MET C 1 194 ? -24.673 6.112   -38.726  1.00 37.18  ? 194 MET C CA    1 
ATOM   9638  C C     . MET C 1 194 ? -25.624 5.026   -38.253  1.00 39.12  ? 194 MET C C     1 
ATOM   9639  O O     . MET C 1 194 ? -26.048 5.092   -37.105  1.00 42.91  ? 194 MET C O     1 
ATOM   9640  C CB    . MET C 1 194 ? -25.492 7.400   -38.896  1.00 39.09  ? 194 MET C CB    1 
ATOM   9641  C CG    . MET C 1 194 ? -24.665 8.621   -39.227  1.00 41.22  ? 194 MET C CG    1 
ATOM   9642  S SD    . MET C 1 194 ? -23.240 8.818   -38.151  1.00 42.45  ? 194 MET C SD    1 
ATOM   9643  C CE    . MET C 1 194 ? -24.047 8.951   -36.552  1.00 41.21  ? 194 MET C CE    1 
ATOM   9644  N N     . GLY C 1 195 ? -25.975 4.085   -39.153  1.00 36.98  ? 195 GLY C N     1 
ATOM   9645  C CA    . GLY C 1 195 ? -26.811 2.928   -38.854  1.00 37.05  ? 195 GLY C CA    1 
ATOM   9646  C C     . GLY C 1 195 ? -26.206 1.930   -37.847  1.00 40.95  ? 195 GLY C C     1 
ATOM   9647  O O     . GLY C 1 195 ? -26.929 1.138   -37.238  1.00 39.01  ? 195 GLY C O     1 
ATOM   9648  N N     . ALA C 1 196 ? -24.877 1.924   -37.673  1.00 39.94  ? 196 ALA C N     1 
ATOM   9649  C CA    . ALA C 1 196 ? -24.261 1.159   -36.597  1.00 36.21  ? 196 ALA C CA    1 
ATOM   9650  C C     . ALA C 1 196 ? -24.635 1.741   -35.226  1.00 39.83  ? 196 ALA C C     1 
ATOM   9651  O O     . ALA C 1 196 ? -24.470 1.075   -34.194  1.00 35.38  ? 196 ALA C O     1 
ATOM   9652  C CB    . ALA C 1 196 ? -22.756 1.100   -36.779  1.00 35.46  ? 196 ALA C CB    1 
ATOM   9653  N N     . MET C 1 197 ? -25.136 2.989   -35.198  1.00 43.64  ? 197 MET C N     1 
ATOM   9654  C CA    . MET C 1 197 ? -25.538 3.597   -33.934  1.00 44.18  ? 197 MET C CA    1 
ATOM   9655  C C     . MET C 1 197 ? -27.026 3.313   -33.705  1.00 42.91  ? 197 MET C C     1 
ATOM   9656  O O     . MET C 1 197 ? -27.882 3.766   -34.441  1.00 40.82  ? 197 MET C O     1 
ATOM   9657  C CB    . MET C 1 197 ? -25.265 5.111   -33.879  1.00 39.58  ? 197 MET C CB    1 
ATOM   9658  C CG    . MET C 1 197 ? -26.080 5.824   -32.818  1.00 42.79  ? 197 MET C CG    1 
ATOM   9659  S SD    . MET C 1 197 ? -25.743 7.592   -32.521  1.00 45.02  ? 197 MET C SD    1 
ATOM   9660  C CE    . MET C 1 197 ? -24.237 7.410   -31.572  1.00 61.83  ? 197 MET C CE    1 
ATOM   9661  N N     . PRO C 1 198 ? -27.417 2.595   -32.639  1.00 44.08  ? 198 PRO C N     1 
ATOM   9662  C CA    . PRO C 1 198 ? -28.839 2.489   -32.321  1.00 44.95  ? 198 PRO C CA    1 
ATOM   9663  C C     . PRO C 1 198 ? -29.400 3.859   -31.919  1.00 43.94  ? 198 PRO C C     1 
ATOM   9664  O O     . PRO C 1 198 ? -28.706 4.681   -31.307  1.00 44.84  ? 198 PRO C O     1 
ATOM   9665  C CB    . PRO C 1 198 ? -28.896 1.495   -31.143  1.00 45.93  ? 198 PRO C CB    1 
ATOM   9666  C CG    . PRO C 1 198 ? -27.474 0.979   -30.943  1.00 47.69  ? 198 PRO C CG    1 
ATOM   9667  C CD    . PRO C 1 198 ? -26.539 1.947   -31.648  1.00 42.55  ? 198 PRO C CD    1 
ATOM   9668  N N     . GLY C 1 199 ? -30.660 4.101   -32.286  1.00 40.19  ? 199 GLY C N     1 
ATOM   9669  C CA    . GLY C 1 199 ? -31.362 5.300   -31.883  1.00 44.77  ? 199 GLY C CA    1 
ATOM   9670  C C     . GLY C 1 199 ? -31.149 6.480   -32.825  1.00 49.92  ? 199 GLY C C     1 
ATOM   9671  O O     . GLY C 1 199 ? -31.683 7.555   -32.576  1.00 57.95  ? 199 GLY C O     1 
ATOM   9672  N N     . ASN C 1 200 ? -30.406 6.271   -33.913  1.00 49.38  ? 200 ASN C N     1 
ATOM   9673  C CA    . ASN C 1 200 ? -30.035 7.342   -34.825  1.00 48.15  ? 200 ASN C CA    1 
ATOM   9674  C C     . ASN C 1 200 ? -31.231 7.687   -35.706  1.00 43.84  ? 200 ASN C C     1 
ATOM   9675  O O     . ASN C 1 200 ? -32.053 6.835   -35.981  1.00 39.31  ? 200 ASN C O     1 
ATOM   9676  C CB    . ASN C 1 200 ? -28.878 6.944   -35.753  1.00 48.13  ? 200 ASN C CB    1 
ATOM   9677  C CG    . ASN C 1 200 ? -29.342 6.040   -36.889  1.00 47.80  ? 200 ASN C CG    1 
ATOM   9678  O OD1   . ASN C 1 200 ? -29.985 6.495   -37.837  1.00 55.04  ? 200 ASN C OD1   1 
ATOM   9679  N ND2   . ASN C 1 200 ? -29.086 4.747   -36.785  1.00 40.21  ? 200 ASN C ND2   1 
ATOM   9680  N N     . ASN C 1 201 ? -31.243 8.910   -36.232  1.00 46.74  ? 201 ASN C N     1 
ATOM   9681  C CA    . ASN C 1 201 ? -32.109 9.254   -37.342  1.00 44.98  ? 201 ASN C CA    1 
ATOM   9682  C C     . ASN C 1 201 ? -31.277 9.801   -38.489  1.00 43.88  ? 201 ASN C C     1 
ATOM   9683  O O     . ASN C 1 201 ? -31.802 10.608  -39.250  1.00 50.36  ? 201 ASN C O     1 
ATOM   9684  C CB    . ASN C 1 201 ? -33.154 10.295  -36.942  1.00 46.73  ? 201 ASN C CB    1 
ATOM   9685  C CG    . ASN C 1 201 ? -34.175 9.715   -35.994  1.00 45.79  ? 201 ASN C CG    1 
ATOM   9686  O OD1   . ASN C 1 201 ? -34.075 9.894   -34.791  1.00 51.81  ? 201 ASN C OD1   1 
ATOM   9687  N ND2   . ASN C 1 201 ? -35.122 8.967   -36.521  1.00 44.46  ? 201 ASN C ND2   1 
ATOM   9688  N N     . THR C 1 202 ? -30.010 9.360   -38.596  1.00 40.08  ? 202 THR C N     1 
ATOM   9689  C CA    . THR C 1 202 ? -29.070 9.950   -39.540  1.00 43.44  ? 202 THR C CA    1 
ATOM   9690  C C     . THR C 1 202 ? -28.473 8.981   -40.571  1.00 36.47  ? 202 THR C C     1 
ATOM   9691  O O     . THR C 1 202 ? -27.600 9.397   -41.325  1.00 35.88  ? 202 THR C O     1 
ATOM   9692  C CB    . THR C 1 202 ? -27.939 10.635  -38.766  1.00 44.33  ? 202 THR C CB    1 
ATOM   9693  O OG1   . THR C 1 202 ? -27.296 9.670   -37.925  1.00 41.36  ? 202 THR C OG1   1 
ATOM   9694  C CG2   . THR C 1 202 ? -28.482 11.789  -37.959  1.00 48.29  ? 202 THR C CG2   1 
ATOM   9695  N N     . TRP C 1 203 ? -28.933 7.723   -40.611  1.00 37.13  ? 203 TRP C N     1 
ATOM   9696  C CA    . TRP C 1 203 ? -28.460 6.697   -41.548  1.00 38.22  ? 203 TRP C CA    1 
ATOM   9697  C C     . TRP C 1 203 ? -28.343 7.222   -42.980  1.00 36.76  ? 203 TRP C C     1 
ATOM   9698  O O     . TRP C 1 203 ? -27.357 6.979   -43.658  1.00 34.85  ? 203 TRP C O     1 
ATOM   9699  C CB    . TRP C 1 203 ? -29.416 5.496   -41.561  1.00 36.88  ? 203 TRP C CB    1 
ATOM   9700  C CG    . TRP C 1 203 ? -28.781 4.197   -41.922  1.00 34.55  ? 203 TRP C CG    1 
ATOM   9701  C CD1   . TRP C 1 203 ? -27.455 3.959   -42.137  1.00 37.28  ? 203 TRP C CD1   1 
ATOM   9702  C CD2   . TRP C 1 203 ? -29.436 2.922   -41.979  1.00 33.13  ? 203 TRP C CD2   1 
ATOM   9703  N NE1   . TRP C 1 203 ? -27.249 2.620   -42.346  1.00 36.19  ? 203 TRP C NE1   1 
ATOM   9704  C CE2   . TRP C 1 203 ? -28.445 1.959   -42.262  1.00 35.59  ? 203 TRP C CE2   1 
ATOM   9705  C CE3   . TRP C 1 203 ? -30.760 2.492   -41.822  1.00 35.46  ? 203 TRP C CE3   1 
ATOM   9706  C CZ2   . TRP C 1 203 ? -28.739 0.594   -42.371  1.00 42.65  ? 203 TRP C CZ2   1 
ATOM   9707  C CZ3   . TRP C 1 203 ? -31.061 1.151   -41.978  1.00 35.98  ? 203 TRP C CZ3   1 
ATOM   9708  C CH2   . TRP C 1 203 ? -30.062 0.210   -42.234  1.00 39.01  ? 203 TRP C CH2   1 
ATOM   9709  N N     . GLN C 1 204 ? -29.390 7.897   -43.451  1.00 36.47  ? 204 GLN C N     1 
ATOM   9710  C CA    . GLN C 1 204 ? -29.447 8.361   -44.832  1.00 37.62  ? 204 GLN C CA    1 
ATOM   9711  C C     . GLN C 1 204 ? -28.985 9.813   -44.950  1.00 36.52  ? 204 GLN C C     1 
ATOM   9712  O O     . GLN C 1 204 ? -29.218 10.433  -45.986  1.00 40.60  ? 204 GLN C O     1 
ATOM   9713  C CB    . GLN C 1 204 ? -30.886 8.154   -45.342  1.00 35.45  ? 204 GLN C CB    1 
ATOM   9714  C CG    . GLN C 1 204 ? -31.175 6.728   -45.834  1.00 34.86  ? 204 GLN C CG    1 
ATOM   9715  C CD    . GLN C 1 204 ? -31.095 5.626   -44.796  1.00 33.95  ? 204 GLN C CD    1 
ATOM   9716  O OE1   . GLN C 1 204 ? -31.930 5.507   -43.905  1.00 41.21  ? 204 GLN C OE1   1 
ATOM   9717  N NE2   . GLN C 1 204 ? -30.065 4.804   -44.869  1.00 32.87  ? 204 GLN C NE2   1 
ATOM   9718  N N     . LEU C 1 205 ? -28.348 10.386  -43.912  1.00 32.24  ? 205 LEU C N     1 
ATOM   9719  C CA    . LEU C 1 205 ? -28.047 11.805  -43.954  1.00 32.94  ? 205 LEU C CA    1 
ATOM   9720  C C     . LEU C 1 205 ? -26.556 12.089  -43.965  1.00 36.20  ? 205 LEU C C     1 
ATOM   9721  O O     . LEU C 1 205 ? -26.147 13.187  -44.354  1.00 37.18  ? 205 LEU C O     1 
ATOM   9722  C CB    . LEU C 1 205 ? -28.658 12.488  -42.746  1.00 40.21  ? 205 LEU C CB    1 
ATOM   9723  C CG    . LEU C 1 205 ? -30.177 12.451  -42.624  1.00 36.26  ? 205 LEU C CG    1 
ATOM   9724  C CD1   . LEU C 1 205 ? -30.563 13.114  -41.311  1.00 35.38  ? 205 LEU C CD1   1 
ATOM   9725  C CD2   . LEU C 1 205 ? -30.855 13.154  -43.790  1.00 37.83  ? 205 LEU C CD2   1 
ATOM   9726  N N     . PHE C 1 206 ? -25.755 11.105  -43.556  1.00 37.85  ? 206 PHE C N     1 
ATOM   9727  C CA    . PHE C 1 206 ? -24.321 11.298  -43.396  1.00 37.13  ? 206 PHE C CA    1 
ATOM   9728  C C     . PHE C 1 206 ? -23.644 9.965   -43.678  1.00 36.02  ? 206 PHE C C     1 
ATOM   9729  O O     . PHE C 1 206 ? -23.906 9.014   -42.966  1.00 40.99  ? 206 PHE C O     1 
ATOM   9730  C CB    . PHE C 1 206 ? -24.038 11.810  -41.980  1.00 37.26  ? 206 PHE C CB    1 
ATOM   9731  C CG    . PHE C 1 206 ? -22.587 12.035  -41.666  1.00 33.89  ? 206 PHE C CG    1 
ATOM   9732  C CD1   . PHE C 1 206 ? -21.912 13.116  -42.207  1.00 32.58  ? 206 PHE C CD1   1 
ATOM   9733  C CD2   . PHE C 1 206 ? -21.884 11.138  -40.869  1.00 35.44  ? 206 PHE C CD2   1 
ATOM   9734  C CE1   . PHE C 1 206 ? -20.557 13.305  -41.956  1.00 33.00  ? 206 PHE C CE1   1 
ATOM   9735  C CE2   . PHE C 1 206 ? -20.523 11.314  -40.628  1.00 37.60  ? 206 PHE C CE2   1 
ATOM   9736  C CZ    . PHE C 1 206 ? -19.859 12.414  -41.164  1.00 34.63  ? 206 PHE C CZ    1 
ATOM   9737  N N     . LYS C 1 207 ? -22.820 9.905   -44.731  1.00 39.01  ? 207 LYS C N     1 
ATOM   9738  C CA    . LYS C 1 207 ? -22.275 8.662   -45.253  1.00 35.19  ? 207 LYS C CA    1 
ATOM   9739  C C     . LYS C 1 207 ? -21.310 7.977   -44.287  1.00 40.55  ? 207 LYS C C     1 
ATOM   9740  O O     . LYS C 1 207 ? -21.333 6.753   -44.179  1.00 40.66  ? 207 LYS C O     1 
ATOM   9741  C CB    . LYS C 1 207 ? -21.435 8.914   -46.504  1.00 33.25  ? 207 LYS C CB    1 
ATOM   9742  C CG    . LYS C 1 207 ? -22.228 9.132   -47.776  1.00 34.89  ? 207 LYS C CG    1 
ATOM   9743  C CD    . LYS C 1 207 ? -21.320 9.582   -48.897  1.00 35.10  ? 207 LYS C CD    1 
ATOM   9744  C CE    . LYS C 1 207 ? -21.954 9.512   -50.267  1.00 36.09  ? 207 LYS C CE    1 
ATOM   9745  N NZ    . LYS C 1 207 ? -21.551 8.271   -50.962  1.00 39.02  ? 207 LYS C NZ    1 
ATOM   9746  N N     . TYR C 1 208 ? -20.397 8.733   -43.650  1.00 43.85  ? 208 TYR C N     1 
ATOM   9747  C CA    . TYR C 1 208 ? -19.191 8.105   -43.112  1.00 43.38  ? 208 TYR C CA    1 
ATOM   9748  C C     . TYR C 1 208 ? -19.474 7.281   -41.870  1.00 41.73  ? 208 TYR C C     1 
ATOM   9749  O O     . TYR C 1 208 ? -18.915 6.208   -41.705  1.00 43.05  ? 208 TYR C O     1 
ATOM   9750  C CB    . TYR C 1 208 ? -18.099 9.119   -42.764  1.00 45.22  ? 208 TYR C CB    1 
ATOM   9751  C CG    . TYR C 1 208 ? -17.582 9.854   -43.969  1.00 49.05  ? 208 TYR C CG    1 
ATOM   9752  C CD1   . TYR C 1 208 ? -17.209 9.173   -45.121  1.00 48.91  ? 208 TYR C CD1   1 
ATOM   9753  C CD2   . TYR C 1 208 ? -17.539 11.236  -43.990  1.00 52.26  ? 208 TYR C CD2   1 
ATOM   9754  C CE1   . TYR C 1 208 ? -16.771 9.855   -46.245  1.00 53.78  ? 208 TYR C CE1   1 
ATOM   9755  C CE2   . TYR C 1 208 ? -17.101 11.930  -45.106  1.00 54.93  ? 208 TYR C CE2   1 
ATOM   9756  C CZ    . TYR C 1 208 ? -16.707 11.237  -46.232  1.00 50.78  ? 208 TYR C CZ    1 
ATOM   9757  O OH    . TYR C 1 208 ? -16.245 11.942  -47.297  1.00 53.06  ? 208 TYR C OH    1 
ATOM   9758  N N     . GLY C 1 209 ? -20.326 7.802   -40.989  1.00 43.39  ? 209 GLY C N     1 
ATOM   9759  C CA    . GLY C 1 209 ? -20.263 7.387   -39.598  1.00 47.27  ? 209 GLY C CA    1 
ATOM   9760  C C     . GLY C 1 209 ? -18.884 7.702   -39.023  1.00 41.62  ? 209 GLY C C     1 
ATOM   9761  O O     . GLY C 1 209 ? -18.335 8.776   -39.260  1.00 46.22  ? 209 GLY C O     1 
ATOM   9762  N N     . TYR C 1 210 ? -18.313 6.727   -38.326  1.00 38.70  ? 210 TYR C N     1 
ATOM   9763  C CA    . TYR C 1 210 ? -17.016 6.878   -37.693  1.00 37.49  ? 210 TYR C CA    1 
ATOM   9764  C C     . TYR C 1 210 ? -16.181 5.681   -38.099  1.00 33.83  ? 210 TYR C C     1 
ATOM   9765  O O     . TYR C 1 210 ? -16.715 4.587   -38.293  1.00 34.86  ? 210 TYR C O     1 
ATOM   9766  C CB    . TYR C 1 210 ? -17.197 6.936   -36.179  1.00 39.86  ? 210 TYR C CB    1 
ATOM   9767  C CG    . TYR C 1 210 ? -15.928 6.867   -35.374  1.00 41.61  ? 210 TYR C CG    1 
ATOM   9768  C CD1   . TYR C 1 210 ? -14.971 7.865   -35.463  1.00 42.85  ? 210 TYR C CD1   1 
ATOM   9769  C CD2   . TYR C 1 210 ? -15.704 5.818   -34.496  1.00 44.51  ? 210 TYR C CD2   1 
ATOM   9770  C CE1   . TYR C 1 210 ? -13.822 7.833   -34.695  1.00 41.18  ? 210 TYR C CE1   1 
ATOM   9771  C CE2   . TYR C 1 210 ? -14.574 5.780   -33.701  1.00 45.17  ? 210 TYR C CE2   1 
ATOM   9772  C CZ    . TYR C 1 210 ? -13.632 6.791   -33.808  1.00 47.10  ? 210 TYR C CZ    1 
ATOM   9773  O OH    . TYR C 1 210 ? -12.492 6.740   -33.054  1.00 52.73  ? 210 TYR C OH    1 
ATOM   9774  N N     . GLY C 1 211 ? -14.887 5.911   -38.288  1.00 32.26  ? 211 GLY C N     1 
ATOM   9775  C CA    . GLY C 1 211 ? -13.981 4.814   -38.590  1.00 36.28  ? 211 GLY C CA    1 
ATOM   9776  C C     . GLY C 1 211 ? -13.872 4.522   -40.086  1.00 35.17  ? 211 GLY C C     1 
ATOM   9777  O O     . GLY C 1 211 ? -14.175 5.370   -40.907  1.00 34.03  ? 211 GLY C O     1 
ATOM   9778  N N     . PRO C 1 212 ? -13.333 3.357   -40.484  1.00 38.91  ? 212 PRO C N     1 
ATOM   9779  C CA    . PRO C 1 212 ? -13.157 3.042   -41.899  1.00 41.01  ? 212 PRO C CA    1 
ATOM   9780  C C     . PRO C 1 212 ? -14.456 3.198   -42.691  1.00 42.39  ? 212 PRO C C     1 
ATOM   9781  O O     . PRO C 1 212 ? -15.528 2.759   -42.252  1.00 47.74  ? 212 PRO C O     1 
ATOM   9782  C CB    . PRO C 1 212 ? -12.707 1.573   -41.852  1.00 49.24  ? 212 PRO C CB    1 
ATOM   9783  C CG    . PRO C 1 212 ? -12.029 1.402   -40.512  1.00 47.66  ? 212 PRO C CG    1 
ATOM   9784  C CD    . PRO C 1 212 ? -12.817 2.306   -39.588  1.00 45.58  ? 212 PRO C CD    1 
ATOM   9785  N N     . TYR C 1 213 ? -14.360 3.857   -43.845  1.00 38.37  ? 213 TYR C N     1 
ATOM   9786  C CA    . TYR C 1 213 ? -15.473 3.963   -44.763  1.00 42.52  ? 213 TYR C CA    1 
ATOM   9787  C C     . TYR C 1 213 ? -15.476 2.723   -45.660  1.00 40.24  ? 213 TYR C C     1 
ATOM   9788  O O     . TYR C 1 213 ? -14.630 2.611   -46.540  1.00 44.90  ? 213 TYR C O     1 
ATOM   9789  C CB    . TYR C 1 213 ? -15.402 5.268   -45.563  1.00 44.80  ? 213 TYR C CB    1 
ATOM   9790  C CG    . TYR C 1 213 ? -16.596 5.521   -46.458  1.00 49.77  ? 213 TYR C CG    1 
ATOM   9791  C CD1   . TYR C 1 213 ? -17.876 5.220   -46.035  1.00 40.94  ? 213 TYR C CD1   1 
ATOM   9792  C CD2   . TYR C 1 213 ? -16.458 6.109   -47.708  1.00 58.76  ? 213 TYR C CD2   1 
ATOM   9793  C CE1   . TYR C 1 213 ? -18.972 5.461   -46.837  1.00 50.37  ? 213 TYR C CE1   1 
ATOM   9794  C CE2   . TYR C 1 213 ? -17.549 6.379   -48.519  1.00 55.38  ? 213 TYR C CE2   1 
ATOM   9795  C CZ    . TYR C 1 213 ? -18.815 6.035   -48.087  1.00 53.19  ? 213 TYR C CZ    1 
ATOM   9796  O OH    . TYR C 1 213 ? -19.956 6.281   -48.808  1.00 54.40  ? 213 TYR C OH    1 
ATOM   9797  N N     . VAL C 1 214 ? -16.464 1.843   -45.450  1.00 37.99  ? 214 VAL C N     1 
ATOM   9798  C CA    . VAL C 1 214 ? -16.503 0.503   -46.003  1.00 40.15  ? 214 VAL C CA    1 
ATOM   9799  C C     . VAL C 1 214 ? -17.703 0.261   -46.923  1.00 40.13  ? 214 VAL C C     1 
ATOM   9800  O O     . VAL C 1 214 ? -17.838 -0.853  -47.403  1.00 41.13  ? 214 VAL C O     1 
ATOM   9801  C CB    . VAL C 1 214 ? -16.582 -0.529  -44.872  1.00 44.70  ? 214 VAL C CB    1 
ATOM   9802  C CG1   . VAL C 1 214 ? -15.302 -0.567  -44.046  1.00 52.17  ? 214 VAL C CG1   1 
ATOM   9803  C CG2   . VAL C 1 214 ? -17.819 -0.292  -44.016  1.00 41.40  ? 214 VAL C CG2   1 
ATOM   9804  N N     . ASP C 1 215 ? -18.624 1.213   -47.133  1.00 40.96  ? 215 ASP C N     1 
ATOM   9805  C CA    . ASP C 1 215 ? -19.778 0.904   -47.981  1.00 44.04  ? 215 ASP C CA    1 
ATOM   9806  C C     . ASP C 1 215 ? -19.260 0.441   -49.349  1.00 41.76  ? 215 ASP C C     1 
ATOM   9807  O O     . ASP C 1 215 ? -19.744 -0.554  -49.905  1.00 37.84  ? 215 ASP C O     1 
ATOM   9808  C CB    . ASP C 1 215 ? -20.780 2.060   -48.117  1.00 39.88  ? 215 ASP C CB    1 
ATOM   9809  C CG    . ASP C 1 215 ? -21.431 2.425   -46.798  1.00 42.24  ? 215 ASP C CG    1 
ATOM   9810  O OD1   . ASP C 1 215 ? -20.689 2.907   -45.941  1.00 49.77  ? 215 ASP C OD1   1 
ATOM   9811  O OD2   . ASP C 1 215 ? -22.694 2.242   -46.631  1.00 42.09  ? 215 ASP C OD2   1 
ATOM   9812  N N     . GLY C 1 216 ? -18.210 1.131   -49.827  1.00 37.85  ? 216 GLY C N     1 
ATOM   9813  C CA    . GLY C 1 216 ? -17.616 0.899   -51.140  1.00 39.22  ? 216 GLY C CA    1 
ATOM   9814  C C     . GLY C 1 216 ? -17.226 -0.561  -51.367  1.00 41.51  ? 216 GLY C C     1 
ATOM   9815  O O     . GLY C 1 216 ? -17.300 -1.047  -52.501  1.00 44.82  ? 216 GLY C O     1 
ATOM   9816  N N     . ILE C 1 217 ? -16.873 -1.276  -50.288  1.00 36.75  ? 217 ILE C N     1 
ATOM   9817  C CA    . ILE C 1 217 ? -16.306 -2.601  -50.468  1.00 41.62  ? 217 ILE C CA    1 
ATOM   9818  C C     . ILE C 1 217 ? -17.402 -3.603  -50.826  1.00 43.33  ? 217 ILE C C     1 
ATOM   9819  O O     . ILE C 1 217 ? -17.085 -4.689  -51.296  1.00 48.18  ? 217 ILE C O     1 
ATOM   9820  C CB    . ILE C 1 217 ? -15.431 -3.068  -49.280  1.00 42.06  ? 217 ILE C CB    1 
ATOM   9821  C CG1   . ILE C 1 217 ? -16.231 -3.595  -48.087  1.00 42.73  ? 217 ILE C CG1   1 
ATOM   9822  C CG2   . ILE C 1 217 ? -14.430 -1.992  -48.867  1.00 42.48  ? 217 ILE C CG2   1 
ATOM   9823  C CD1   . ILE C 1 217 ? -15.423 -4.519  -47.200  1.00 41.82  ? 217 ILE C CD1   1 
ATOM   9824  N N     . PHE C 1 218 ? -18.676 -3.228  -50.655  1.00 46.87  ? 218 PHE C N     1 
ATOM   9825  C CA    . PHE C 1 218 ? -19.785 -4.093  -51.027  1.00 45.29  ? 218 PHE C CA    1 
ATOM   9826  C C     . PHE C 1 218 ? -20.369 -3.731  -52.390  1.00 47.24  ? 218 PHE C C     1 
ATOM   9827  O O     . PHE C 1 218 ? -21.428 -4.258  -52.725  1.00 47.88  ? 218 PHE C O     1 
ATOM   9828  C CB    . PHE C 1 218 ? -20.877 -4.022  -49.957  1.00 43.85  ? 218 PHE C CB    1 
ATOM   9829  C CG    . PHE C 1 218 ? -20.354 -4.432  -48.609  1.00 43.63  ? 218 PHE C CG    1 
ATOM   9830  C CD1   . PHE C 1 218 ? -19.869 -5.704  -48.412  1.00 40.37  ? 218 PHE C CD1   1 
ATOM   9831  C CD2   . PHE C 1 218 ? -20.251 -3.521  -47.580  1.00 41.33  ? 218 PHE C CD2   1 
ATOM   9832  C CE1   . PHE C 1 218 ? -19.340 -6.078  -47.192  1.00 42.55  ? 218 PHE C CE1   1 
ATOM   9833  C CE2   . PHE C 1 218 ? -19.695 -3.891  -46.373  1.00 40.76  ? 218 PHE C CE2   1 
ATOM   9834  C CZ    . PHE C 1 218 ? -19.244 -5.166  -46.182  1.00 41.09  ? 218 PHE C CZ    1 
ATOM   9835  N N     . SER C 1 219 ? -19.717 -2.821  -53.144  1.00 47.93  ? 219 SER C N     1 
ATOM   9836  C CA    . SER C 1 219 ? -20.097 -2.548  -54.526  1.00 41.46  ? 219 SER C CA    1 
ATOM   9837  C C     . SER C 1 219 ? -19.156 -3.311  -55.459  1.00 43.28  ? 219 SER C C     1 
ATOM   9838  O O     . SER C 1 219 ? -17.998 -3.530  -55.116  1.00 39.67  ? 219 SER C O     1 
ATOM   9839  C CB    . SER C 1 219 ? -20.129 -1.064  -54.802  1.00 41.12  ? 219 SER C CB    1 
ATOM   9840  O OG    . SER C 1 219 ? -18.834 -0.528  -54.972  1.00 42.18  ? 219 SER C OG    1 
ATOM   9841  N N     . GLN C 1 220 ? -19.671 -3.738  -56.627  1.00 45.59  ? 220 GLN C N     1 
ATOM   9842  C CA    . GLN C 1 220 ? -18.982 -4.652  -57.542  1.00 42.97  ? 220 GLN C CA    1 
ATOM   9843  C C     . GLN C 1 220 ? -18.149 -5.666  -56.768  1.00 49.41  ? 220 GLN C C     1 
ATOM   9844  O O     . GLN C 1 220 ? -16.945 -5.813  -57.007  1.00 49.05  ? 220 GLN C O     1 
ATOM   9845  C CB    . GLN C 1 220 ? -18.097 -3.932  -58.557  1.00 44.08  ? 220 GLN C CB    1 
ATOM   9846  C CG    . GLN C 1 220 ? -18.907 -3.290  -59.664  1.00 48.42  ? 220 GLN C CG    1 
ATOM   9847  C CD    . GLN C 1 220 ? -18.071 -2.639  -60.733  1.00 46.74  ? 220 GLN C CD    1 
ATOM   9848  O OE1   . GLN C 1 220 ? -16.841 -2.640  -60.691  1.00 44.02  ? 220 GLN C OE1   1 
ATOM   9849  N NE2   . GLN C 1 220 ? -18.767 -2.036  -61.684  1.00 47.34  ? 220 GLN C NE2   1 
ATOM   9850  N N     . SER C 1 221 ? -18.822 -6.419  -55.894  1.00 48.27  ? 221 SER C N     1 
ATOM   9851  C CA    . SER C 1 221 ? -18.105 -7.142  -54.862  1.00 52.41  ? 221 SER C CA    1 
ATOM   9852  C C     . SER C 1 221 ? -18.716 -8.515  -54.662  1.00 42.04  ? 221 SER C C     1 
ATOM   9853  O O     . SER C 1 221 ? -19.885 -8.694  -54.937  1.00 45.88  ? 221 SER C O     1 
ATOM   9854  C CB    . SER C 1 221 ? -18.108 -6.337  -53.585  1.00 54.68  ? 221 SER C CB    1 
ATOM   9855  O OG    . SER C 1 221 ? -17.787 -7.160  -52.480  1.00 64.54  ? 221 SER C OG    1 
ATOM   9856  N N     . ASN C 1 222 ? -17.936 -9.464  -54.143  1.00 42.70  ? 222 ASN C N     1 
ATOM   9857  C CA    . ASN C 1 222 ? -18.540 -10.639 -53.529  1.00 42.96  ? 222 ASN C CA    1 
ATOM   9858  C C     . ASN C 1 222 ? -18.211 -10.698 -52.036  1.00 44.45  ? 222 ASN C C     1 
ATOM   9859  O O     . ASN C 1 222 ? -17.953 -11.782 -51.522  1.00 49.96  ? 222 ASN C O     1 
ATOM   9860  C CB    . ASN C 1 222 ? -18.155 -11.913 -54.281  1.00 40.15  ? 222 ASN C CB    1 
ATOM   9861  C CG    . ASN C 1 222 ? -16.665 -12.113 -54.433  1.00 44.91  ? 222 ASN C CG    1 
ATOM   9862  O OD1   . ASN C 1 222 ? -15.849 -11.333 -53.946  1.00 47.45  ? 222 ASN C OD1   1 
ATOM   9863  N ND2   . ASN C 1 222 ? -16.297 -13.183 -55.111  1.00 51.37  ? 222 ASN C ND2   1 
ATOM   9864  N N     . PHE C 1 223 ? -18.242 -9.546  -51.333  1.00 47.52  ? 223 PHE C N     1 
ATOM   9865  C CA    . PHE C 1 223 ? -17.848 -9.474  -49.925  1.00 46.78  ? 223 PHE C CA    1 
ATOM   9866  C C     . PHE C 1 223 ? -19.038 -9.500  -48.971  1.00 43.42  ? 223 PHE C C     1 
ATOM   9867  O O     . PHE C 1 223 ? -18.836 -9.597  -47.773  1.00 44.37  ? 223 PHE C O     1 
ATOM   9868  C CB    . PHE C 1 223 ? -17.058 -8.203  -49.626  1.00 47.16  ? 223 PHE C CB    1 
ATOM   9869  C CG    . PHE C 1 223 ? -15.700 -8.163  -50.273  1.00 45.53  ? 223 PHE C CG    1 
ATOM   9870  C CD1   . PHE C 1 223 ? -15.129 -9.310  -50.809  1.00 44.55  ? 223 PHE C CD1   1 
ATOM   9871  C CD2   . PHE C 1 223 ? -15.011 -6.968  -50.363  1.00 40.84  ? 223 PHE C CD2   1 
ATOM   9872  C CE1   . PHE C 1 223 ? -13.892 -9.255  -51.429  1.00 43.21  ? 223 PHE C CE1   1 
ATOM   9873  C CE2   . PHE C 1 223 ? -13.777 -6.913  -50.985  1.00 43.74  ? 223 PHE C CE2   1 
ATOM   9874  C CZ    . PHE C 1 223 ? -13.221 -8.054  -51.510  1.00 46.31  ? 223 PHE C CZ    1 
ATOM   9875  N N     . GLY C 1 224 ? -20.259 -9.387  -49.501  1.00 37.33  ? 224 GLY C N     1 
ATOM   9876  C CA    . GLY C 1 224 ? -21.446 -9.438  -48.677  1.00 37.10  ? 224 GLY C CA    1 
ATOM   9877  C C     . GLY C 1 224 ? -22.712 -9.287  -49.515  1.00 37.71  ? 224 GLY C C     1 
ATOM   9878  O O     . GLY C 1 224 ? -22.658 -8.901  -50.674  1.00 43.07  ? 224 GLY C O     1 
ATOM   9879  N N     . VAL C 1 225 ? -23.868 -9.558  -48.900  1.00 42.93  ? 225 VAL C N     1 
ATOM   9880  C CA    . VAL C 1 225 ? -25.143 -9.381  -49.566  1.00 44.23  ? 225 VAL C CA    1 
ATOM   9881  C C     . VAL C 1 225 ? -25.866 -8.203  -48.932  1.00 44.51  ? 225 VAL C C     1 
ATOM   9882  O O     . VAL C 1 225 ? -26.146 -8.202  -47.747  1.00 45.25  ? 225 VAL C O     1 
ATOM   9883  C CB    . VAL C 1 225 ? -25.960 -10.672 -49.446  1.00 52.85  ? 225 VAL C CB    1 
ATOM   9884  C CG1   . VAL C 1 225 ? -27.332 -10.535 -50.104  1.00 50.44  ? 225 VAL C CG1   1 
ATOM   9885  C CG2   . VAL C 1 225 ? -25.166 -11.856 -49.996  1.00 53.53  ? 225 VAL C CG2   1 
ATOM   9886  N N     . VAL C 1 226 ? -26.172 -7.204  -49.747  1.00 43.79  ? 226 VAL C N     1 
ATOM   9887  C CA    . VAL C 1 226 ? -26.796 -5.985  -49.280  1.00 39.15  ? 226 VAL C CA    1 
ATOM   9888  C C     . VAL C 1 226 ? -28.301 -6.202  -49.215  1.00 42.04  ? 226 VAL C C     1 
ATOM   9889  O O     . VAL C 1 226 ? -28.913 -6.514  -50.228  1.00 38.07  ? 226 VAL C O     1 
ATOM   9890  C CB    . VAL C 1 226 ? -26.436 -4.842  -50.241  1.00 39.61  ? 226 VAL C CB    1 
ATOM   9891  C CG1   . VAL C 1 226 ? -27.143 -3.550  -49.880  1.00 42.61  ? 226 VAL C CG1   1 
ATOM   9892  C CG2   . VAL C 1 226 ? -24.930 -4.627  -50.306  1.00 36.26  ? 226 VAL C CG2   1 
ATOM   9893  N N     . THR C 1 227 ? -28.909 -5.926  -48.049  1.00 47.09  ? 227 THR C N     1 
ATOM   9894  C CA    . THR C 1 227 ? -30.334 -6.173  -47.841  1.00 40.81  ? 227 THR C CA    1 
ATOM   9895  C C     . THR C 1 227 ? -31.157 -4.894  -47.729  1.00 40.85  ? 227 THR C C     1 
ATOM   9896  O O     . THR C 1 227 ? -32.378 -4.939  -47.855  1.00 44.81  ? 227 THR C O     1 
ATOM   9897  C CB    . THR C 1 227 ? -30.534 -7.021  -46.587  1.00 40.72  ? 227 THR C CB    1 
ATOM   9898  O OG1   . THR C 1 227 ? -29.803 -6.373  -45.553  1.00 39.20  ? 227 THR C OG1   1 
ATOM   9899  C CG2   . THR C 1 227 ? -30.021 -8.433  -46.751  1.00 42.10  ? 227 THR C CG2   1 
ATOM   9900  N N     . LYS C 1 228 ? -30.512 -3.771  -47.407  1.00 43.67  ? 228 LYS C N     1 
ATOM   9901  C CA    . LYS C 1 228 ? -31.165 -2.467  -47.362  1.00 39.96  ? 228 LYS C CA    1 
ATOM   9902  C C     . LYS C 1 228 ? -30.142 -1.444  -47.837  1.00 38.98  ? 228 LYS C C     1 
ATOM   9903  O O     . LYS C 1 228 ? -28.956 -1.639  -47.616  1.00 34.79  ? 228 LYS C O     1 
ATOM   9904  C CB    . LYS C 1 228 ? -31.564 -2.025  -45.952  1.00 38.75  ? 228 LYS C CB    1 
ATOM   9905  C CG    . LYS C 1 228 ? -32.456 -2.945  -45.141  1.00 39.78  ? 228 LYS C CG    1 
ATOM   9906  C CD    . LYS C 1 228 ? -32.795 -2.327  -43.765  1.00 45.02  ? 228 LYS C CD    1 
ATOM   9907  C CE    . LYS C 1 228 ? -33.902 -3.037  -43.015  1.00 47.67  ? 228 LYS C CE    1 
ATOM   9908  N NZ    . LYS C 1 228 ? -33.600 -4.485  -42.898  1.00 47.31  ? 228 LYS C NZ    1 
ATOM   9909  N N     . MET C 1 229 ? -30.591 -0.352  -48.454  1.00 38.58  ? 229 MET C N     1 
ATOM   9910  C CA    . MET C 1 229 ? -29.640 0.653   -48.879  1.00 39.87  ? 229 MET C CA    1 
ATOM   9911  C C     . MET C 1 229 ? -30.313 2.028   -48.906  1.00 41.71  ? 229 MET C C     1 
ATOM   9912  O O     . MET C 1 229 ? -31.401 2.177   -49.464  1.00 35.32  ? 229 MET C O     1 
ATOM   9913  C CB    . MET C 1 229 ? -29.108 0.300   -50.271  1.00 42.17  ? 229 MET C CB    1 
ATOM   9914  C CG    . MET C 1 229 ? -28.061 1.263   -50.779  1.00 42.05  ? 229 MET C CG    1 
ATOM   9915  S SD    . MET C 1 229 ? -27.473 0.867   -52.439  1.00 46.79  ? 229 MET C SD    1 
ATOM   9916  C CE    . MET C 1 229 ? -28.532 1.937   -53.409  1.00 45.29  ? 229 MET C CE    1 
ATOM   9917  N N     . GLY C 1 230 ? -29.649 3.029   -48.299  1.00 36.65  ? 230 GLY C N     1 
ATOM   9918  C CA    . GLY C 1 230 ? -30.052 4.413   -48.481  1.00 36.69  ? 230 GLY C CA    1 
ATOM   9919  C C     . GLY C 1 230 ? -29.630 4.937   -49.852  1.00 37.19  ? 230 GLY C C     1 
ATOM   9920  O O     . GLY C 1 230 ? -28.544 4.609   -50.314  1.00 36.55  ? 230 GLY C O     1 
ATOM   9921  N N     . ILE C 1 231 ? -30.440 5.821   -50.445  1.00 38.56  ? 231 ILE C N     1 
ATOM   9922  C CA    . ILE C 1 231 ? -29.975 6.643   -51.560  1.00 43.60  ? 231 ILE C CA    1 
ATOM   9923  C C     . ILE C 1 231 ? -30.578 8.048   -51.454  1.00 40.85  ? 231 ILE C C     1 
ATOM   9924  O O     . ILE C 1 231 ? -31.720 8.222   -51.057  1.00 43.08  ? 231 ILE C O     1 
ATOM   9925  C CB    . ILE C 1 231 ? -30.292 5.997   -52.927  1.00 45.94  ? 231 ILE C CB    1 
ATOM   9926  C CG1   . ILE C 1 231 ? -29.533 6.687   -54.061  1.00 50.48  ? 231 ILE C CG1   1 
ATOM   9927  C CG2   . ILE C 1 231 ? -31.795 5.986   -53.202  1.00 49.14  ? 231 ILE C CG2   1 
ATOM   9928  C CD1   . ILE C 1 231 ? -29.568 5.929   -55.388  1.00 52.97  ? 231 ILE C CD1   1 
ATOM   9929  N N     . TRP C 1 232 ? -29.801 9.047   -51.868  1.00 40.06  ? 232 TRP C N     1 
ATOM   9930  C CA    . TRP C 1 232 ? -30.240 10.420  -51.876  1.00 43.19  ? 232 TRP C CA    1 
ATOM   9931  C C     . TRP C 1 232 ? -31.054 10.690  -53.136  1.00 44.88  ? 232 TRP C C     1 
ATOM   9932  O O     . TRP C 1 232 ? -30.695 10.206  -54.205  1.00 52.06  ? 232 TRP C O     1 
ATOM   9933  C CB    . TRP C 1 232 ? -29.031 11.355  -51.774  1.00 45.43  ? 232 TRP C CB    1 
ATOM   9934  C CG    . TRP C 1 232 ? -28.299 11.292  -50.466  1.00 47.26  ? 232 TRP C CG    1 
ATOM   9935  C CD1   . TRP C 1 232 ? -28.792 10.900  -49.257  1.00 42.91  ? 232 TRP C CD1   1 
ATOM   9936  C CD2   . TRP C 1 232 ? -26.914 11.617  -50.247  1.00 45.54  ? 232 TRP C CD2   1 
ATOM   9937  N NE1   . TRP C 1 232 ? -27.817 10.975  -48.306  1.00 45.83  ? 232 TRP C NE1   1 
ATOM   9938  C CE2   . TRP C 1 232 ? -26.656 11.414  -48.878  1.00 43.18  ? 232 TRP C CE2   1 
ATOM   9939  C CE3   . TRP C 1 232 ? -25.871 12.049  -51.077  1.00 42.36  ? 232 TRP C CE3   1 
ATOM   9940  C CZ2   . TRP C 1 232 ? -25.405 11.649  -48.306  1.00 44.28  ? 232 TRP C CZ2   1 
ATOM   9941  C CZ3   . TRP C 1 232 ? -24.629 12.254  -50.514  1.00 50.20  ? 232 TRP C CZ3   1 
ATOM   9942  C CH2   . TRP C 1 232 ? -24.394 12.042  -49.147  1.00 43.24  ? 232 TRP C CH2   1 
ATOM   9943  N N     . LEU C 1 233 ? -32.081 11.540  -52.974  1.00 43.99  ? 233 LEU C N     1 
ATOM   9944  C CA    . LEU C 1 233 ? -33.060 11.886  -53.984  1.00 45.15  ? 233 LEU C CA    1 
ATOM   9945  C C     . LEU C 1 233 ? -33.043 13.396  -54.228  1.00 43.83  ? 233 LEU C C     1 
ATOM   9946  O O     . LEU C 1 233 ? -33.271 14.178  -53.310  1.00 38.60  ? 233 LEU C O     1 
ATOM   9947  C CB    . LEU C 1 233 ? -34.444 11.422  -53.503  1.00 45.07  ? 233 LEU C CB    1 
ATOM   9948  C CG    . LEU C 1 233 ? -34.655 9.905   -53.438  1.00 48.56  ? 233 LEU C CG    1 
ATOM   9949  C CD1   . LEU C 1 233 ? -36.101 9.580   -53.128  1.00 47.23  ? 233 LEU C CD1   1 
ATOM   9950  C CD2   . LEU C 1 233 ? -34.246 9.181   -54.718  1.00 44.78  ? 233 LEU C CD2   1 
ATOM   9951  N N     . MET C 1 234 ? -32.827 13.793  -55.490  1.00 44.70  ? 234 MET C N     1 
ATOM   9952  C CA    . MET C 1 234 ? -32.813 15.200  -55.863  1.00 48.59  ? 234 MET C CA    1 
ATOM   9953  C C     . MET C 1 234 ? -34.187 15.795  -55.627  1.00 43.14  ? 234 MET C C     1 
ATOM   9954  O O     . MET C 1 234 ? -35.161 15.224  -56.071  1.00 43.16  ? 234 MET C O     1 
ATOM   9955  C CB    . MET C 1 234 ? -32.491 15.409  -57.343  1.00 51.32  ? 234 MET C CB    1 
ATOM   9956  C CG    . MET C 1 234 ? -32.320 16.868  -57.711  1.00 52.76  ? 234 MET C CG    1 
ATOM   9957  S SD    . MET C 1 234 ? -31.649 17.092  -59.373  1.00 49.12  ? 234 MET C SD    1 
ATOM   9958  C CE    . MET C 1 234 ? -33.142 17.519  -60.262  1.00 61.54  ? 234 MET C CE    1 
ATOM   9959  N N     . PRO C 1 235 ? -34.306 16.924  -54.896  1.00 43.62  ? 235 PRO C N     1 
ATOM   9960  C CA    . PRO C 1 235 ? -35.577 17.631  -54.789  1.00 42.40  ? 235 PRO C CA    1 
ATOM   9961  C C     . PRO C 1 235 ? -35.966 18.231  -56.139  1.00 49.62  ? 235 PRO C C     1 
ATOM   9962  O O     . PRO C 1 235 ? -35.097 18.636  -56.920  1.00 50.91  ? 235 PRO C O     1 
ATOM   9963  C CB    . PRO C 1 235 ? -35.392 18.735  -53.735  1.00 37.98  ? 235 PRO C CB    1 
ATOM   9964  C CG    . PRO C 1 235 ? -33.905 18.778  -53.468  1.00 42.31  ? 235 PRO C CG    1 
ATOM   9965  C CD    . PRO C 1 235 ? -33.257 17.527  -54.063  1.00 43.55  ? 235 PRO C CD    1 
ATOM   9966  N N     . GLU C 1 236 ? -37.288 18.286  -56.365  1.00 46.27  ? 236 GLU C N     1 
ATOM   9967  C CA    . GLU C 1 236 ? -37.847 18.805  -57.587  1.00 50.56  ? 236 GLU C CA    1 
ATOM   9968  C C     . GLU C 1 236 ? -37.302 20.197  -57.844  1.00 47.50  ? 236 GLU C C     1 
ATOM   9969  O O     . GLU C 1 236 ? -37.529 21.104  -57.053  1.00 47.38  ? 236 GLU C O     1 
ATOM   9970  C CB    . GLU C 1 236 ? -39.368 18.886  -57.483  1.00 61.43  ? 236 GLU C CB    1 
ATOM   9971  C CG    . GLU C 1 236 ? -40.044 19.421  -58.745  1.00 69.27  ? 236 GLU C CG    1 
ATOM   9972  C CD    . GLU C 1 236 ? -41.553 19.218  -58.752  1.00 71.36  ? 236 GLU C CD    1 
ATOM   9973  O OE1   . GLU C 1 236 ? -42.245 19.996  -58.086  1.00 68.70  ? 236 GLU C OE1   1 
ATOM   9974  O OE2   . GLU C 1 236 ? -42.024 18.244  -59.378  1.00 70.08  ? 236 GLU C OE2   1 
ATOM   9975  N N     . PRO C 1 237 ? -36.631 20.424  -58.988  1.00 49.99  ? 237 PRO C N     1 
ATOM   9976  C CA    . PRO C 1 237 ? -36.110 21.747  -59.319  1.00 50.72  ? 237 PRO C CA    1 
ATOM   9977  C C     . PRO C 1 237 ? -37.226 22.705  -59.688  1.00 52.31  ? 237 PRO C C     1 
ATOM   9978  O O     . PRO C 1 237 ? -38.342 22.286  -59.962  1.00 59.48  ? 237 PRO C O     1 
ATOM   9979  C CB    . PRO C 1 237 ? -35.164 21.496  -60.497  1.00 46.92  ? 237 PRO C CB    1 
ATOM   9980  C CG    . PRO C 1 237 ? -35.688 20.239  -61.129  1.00 51.38  ? 237 PRO C CG    1 
ATOM   9981  C CD    . PRO C 1 237 ? -36.306 19.423  -60.010  1.00 52.04  ? 237 PRO C CD    1 
ATOM   9982  N N     . ALA C 1 238 ? -36.888 23.992  -59.699  1.00 56.84  ? 238 ALA C N     1 
ATOM   9983  C CA    . ALA C 1 238 ? -37.845 25.024  -60.049  1.00 60.62  ? 238 ALA C CA    1 
ATOM   9984  C C     . ALA C 1 238 ? -37.922 25.204  -61.562  1.00 66.43  ? 238 ALA C C     1 
ATOM   9985  O O     . ALA C 1 238 ? -38.584 26.135  -62.003  1.00 78.98  ? 238 ALA C O     1 
ATOM   9986  C CB    . ALA C 1 238 ? -37.469 26.320  -59.364  1.00 60.28  ? 238 ALA C CB    1 
ATOM   9987  N N     . GLY C 1 239 ? -37.242 24.352  -62.351  1.00 71.72  ? 239 GLY C N     1 
ATOM   9988  C CA    . GLY C 1 239 ? -37.287 24.458  -63.804  1.00 70.42  ? 239 GLY C CA    1 
ATOM   9989  C C     . GLY C 1 239 ? -36.508 23.353  -64.516  1.00 70.95  ? 239 GLY C C     1 
ATOM   9990  O O     . GLY C 1 239 ? -35.544 22.823  -63.965  1.00 75.93  ? 239 GLY C O     1 
ATOM   9991  N N     . TYR C 1 240 ? -36.913 23.046  -65.761  1.00 65.41  ? 240 TYR C N     1 
ATOM   9992  C CA    . TYR C 1 240 ? -36.275 22.005  -66.550  1.00 62.79  ? 240 TYR C CA    1 
ATOM   9993  C C     . TYR C 1 240 ? -36.393 22.335  -68.035  1.00 60.08  ? 240 TYR C C     1 
ATOM   9994  O O     . TYR C 1 240 ? -37.509 22.435  -68.530  1.00 63.41  ? 240 TYR C O     1 
ATOM   9995  C CB    . TYR C 1 240 ? -36.931 20.659  -66.226  1.00 55.41  ? 240 TYR C CB    1 
ATOM   9996  C CG    . TYR C 1 240 ? -36.453 19.476  -67.032  1.00 51.73  ? 240 TYR C CG    1 
ATOM   9997  C CD1   . TYR C 1 240 ? -35.120 19.100  -67.040  1.00 56.81  ? 240 TYR C CD1   1 
ATOM   9998  C CD2   . TYR C 1 240 ? -37.331 18.709  -67.773  1.00 48.20  ? 240 TYR C CD2   1 
ATOM   9999  C CE1   . TYR C 1 240 ? -34.671 18.003  -67.764  1.00 50.98  ? 240 TYR C CE1   1 
ATOM   10000 C CE2   . TYR C 1 240 ? -36.900 17.619  -68.519  1.00 49.28  ? 240 TYR C CE2   1 
ATOM   10001 C CZ    . TYR C 1 240 ? -35.562 17.269  -68.524  1.00 51.18  ? 240 TYR C CZ    1 
ATOM   10002 O OH    . TYR C 1 240 ? -35.115 16.176  -69.234  1.00 56.53  ? 240 TYR C OH    1 
ATOM   10003 N N     . ARG C 1 241 ? -35.247 22.489  -68.723  1.00 59.71  ? 241 ARG C N     1 
ATOM   10004 C CA    . ARG C 1 241 ? -35.197 22.678  -70.172  1.00 59.58  ? 241 ARG C CA    1 
ATOM   10005 C C     . ARG C 1 241 ? -34.228 21.692  -70.817  1.00 59.57  ? 241 ARG C C     1 
ATOM   10006 O O     . ARG C 1 241 ? -33.011 21.857  -70.738  1.00 67.45  ? 241 ARG C O     1 
ATOM   10007 C CB    . ARG C 1 241 ? -34.714 24.075  -70.563  1.00 59.14  ? 241 ARG C CB    1 
ATOM   10008 C CG    . ARG C 1 241 ? -35.690 25.190  -70.229  1.00 70.00  ? 241 ARG C CG    1 
ATOM   10009 C CD    . ARG C 1 241 ? -35.141 26.573  -70.572  1.00 81.74  ? 241 ARG C CD    1 
ATOM   10010 N NE    . ARG C 1 241 ? -35.889 27.616  -69.871  1.00 90.16  ? 241 ARG C NE    1 
ATOM   10011 C CZ    . ARG C 1 241 ? -35.435 28.833  -69.586  1.00 106.13 ? 241 ARG C CZ    1 
ATOM   10012 N NH1   . ARG C 1 241 ? -34.276 29.247  -70.074  1.00 117.83 ? 241 ARG C NH1   1 
ATOM   10013 N NH2   . ARG C 1 241 ? -36.145 29.629  -68.800  1.00 97.80  ? 241 ARG C NH2   1 
ATOM   10014 N N     . PRO C 1 242 ? -34.715 20.609  -71.457  1.00 59.14  ? 242 PRO C N     1 
ATOM   10015 C CA    . PRO C 1 242 ? -33.851 19.775  -72.299  1.00 60.24  ? 242 PRO C CA    1 
ATOM   10016 C C     . PRO C 1 242 ? -33.475 20.465  -73.610  1.00 64.96  ? 242 PRO C C     1 
ATOM   10017 O O     . PRO C 1 242 ? -34.056 21.487  -73.976  1.00 71.68  ? 242 PRO C O     1 
ATOM   10018 C CB    . PRO C 1 242 ? -34.678 18.505  -72.512  1.00 57.69  ? 242 PRO C CB    1 
ATOM   10019 C CG    . PRO C 1 242 ? -36.115 18.919  -72.280  1.00 53.54  ? 242 PRO C CG    1 
ATOM   10020 C CD    . PRO C 1 242 ? -36.069 20.073  -71.312  1.00 53.28  ? 242 PRO C CD    1 
ATOM   10021 N N     . TYR C 1 243 ? -32.443 19.936  -74.274  1.00 68.84  ? 243 TYR C N     1 
ATOM   10022 C CA    . TYR C 1 243 ? -31.887 20.562  -75.461  1.00 64.09  ? 243 TYR C CA    1 
ATOM   10023 C C     . TYR C 1 243 ? -31.055 19.552  -76.241  1.00 69.61  ? 243 TYR C C     1 
ATOM   10024 O O     . TYR C 1 243 ? -30.624 18.541  -75.688  1.00 67.71  ? 243 TYR C O     1 
ATOM   10025 C CB    . TYR C 1 243 ? -31.046 21.789  -75.090  1.00 68.06  ? 243 TYR C CB    1 
ATOM   10026 C CG    . TYR C 1 243 ? -29.768 21.540  -74.317  1.00 62.11  ? 243 TYR C CG    1 
ATOM   10027 C CD1   . TYR C 1 243 ? -28.607 21.110  -74.938  1.00 62.14  ? 243 TYR C CD1   1 
ATOM   10028 C CD2   . TYR C 1 243 ? -29.701 21.791  -72.959  1.00 63.08  ? 243 TYR C CD2   1 
ATOM   10029 C CE1   . TYR C 1 243 ? -27.432 20.908  -74.225  1.00 60.80  ? 243 TYR C CE1   1 
ATOM   10030 C CE2   . TYR C 1 243 ? -28.538 21.593  -72.229  1.00 56.54  ? 243 TYR C CE2   1 
ATOM   10031 C CZ    . TYR C 1 243 ? -27.397 21.150  -72.865  1.00 56.14  ? 243 TYR C CZ    1 
ATOM   10032 O OH    . TYR C 1 243 ? -26.257 20.959  -72.129  1.00 57.16  ? 243 TYR C OH    1 
ATOM   10033 N N     . LEU C 1 244 ? -30.825 19.853  -77.529  1.00 81.90  ? 244 LEU C N     1 
ATOM   10034 C CA    . LEU C 1 244 ? -30.061 18.970  -78.402  1.00 74.29  ? 244 LEU C CA    1 
ATOM   10035 C C     . LEU C 1 244 ? -29.166 19.789  -79.332  1.00 63.76  ? 244 LEU C C     1 
ATOM   10036 O O     . LEU C 1 244 ? -29.600 20.791  -79.888  1.00 64.60  ? 244 LEU C O     1 
ATOM   10037 C CB    . LEU C 1 244 ? -31.035 18.082  -79.181  1.00 67.74  ? 244 LEU C CB    1 
ATOM   10038 C CG    . LEU C 1 244 ? -30.419 17.248  -80.298  1.00 68.46  ? 244 LEU C CG    1 
ATOM   10039 C CD1   . LEU C 1 244 ? -29.472 16.200  -79.739  1.00 78.15  ? 244 LEU C CD1   1 
ATOM   10040 C CD2   . LEU C 1 244 ? -31.493 16.586  -81.133  1.00 59.26  ? 244 LEU C CD2   1 
ATOM   10041 N N     . ILE C 1 245 ? -27.906 19.357  -79.472  1.00 57.17  ? 245 ILE C N     1 
ATOM   10042 C CA    . ILE C 1 245 ? -26.968 20.011  -80.372  1.00 66.62  ? 245 ILE C CA    1 
ATOM   10043 C C     . ILE C 1 245 ? -26.379 18.964  -81.324  1.00 71.79  ? 245 ILE C C     1 
ATOM   10044 O O     . ILE C 1 245 ? -25.777 17.978  -80.884  1.00 69.44  ? 245 ILE C O     1 
ATOM   10045 C CB    . ILE C 1 245 ? -25.894 20.768  -79.564  1.00 67.03  ? 245 ILE C CB    1 
ATOM   10046 C CG1   . ILE C 1 245 ? -26.567 21.655  -78.514  1.00 71.29  ? 245 ILE C CG1   1 
ATOM   10047 C CG2   . ILE C 1 245 ? -24.943 21.563  -80.466  1.00 61.53  ? 245 ILE C CG2   1 
ATOM   10048 C CD1   . ILE C 1 245 ? -25.624 22.317  -77.544  1.00 72.11  ? 245 ILE C CD1   1 
ATOM   10049 N N     . THR C 1 246 ? -26.573 19.199  -82.635  1.00 66.38  ? 246 THR C N     1 
ATOM   10050 C CA    . THR C 1 246 ? -26.080 18.322  -83.692  1.00 59.64  ? 246 THR C CA    1 
ATOM   10051 C C     . THR C 1 246 ? -24.826 18.933  -84.320  1.00 57.62  ? 246 THR C C     1 
ATOM   10052 O O     . THR C 1 246 ? -24.695 20.158  -84.417  1.00 58.73  ? 246 THR C O     1 
ATOM   10053 C CB    . THR C 1 246 ? -27.179 18.047  -84.735  1.00 62.46  ? 246 THR C CB    1 
ATOM   10054 O OG1   . THR C 1 246 ? -27.683 19.263  -85.292  1.00 58.19  ? 246 THR C OG1   1 
ATOM   10055 C CG2   . THR C 1 246 ? -28.358 17.288  -84.160  1.00 64.46  ? 246 THR C CG2   1 
ATOM   10056 N N     . PHE C 1 247 ? -23.917 18.048  -84.752  1.00 61.61  ? 247 PHE C N     1 
ATOM   10057 C CA    . PHE C 1 247 ? -22.720 18.406  -85.503  1.00 61.95  ? 247 PHE C CA    1 
ATOM   10058 C C     . PHE C 1 247 ? -22.647 17.526  -86.751  1.00 60.59  ? 247 PHE C C     1 
ATOM   10059 O O     . PHE C 1 247 ? -22.926 16.333  -86.648  1.00 51.62  ? 247 PHE C O     1 
ATOM   10060 C CB    . PHE C 1 247 ? -21.496 18.193  -84.609  1.00 66.41  ? 247 PHE C CB    1 
ATOM   10061 C CG    . PHE C 1 247 ? -21.620 18.774  -83.225  1.00 64.15  ? 247 PHE C CG    1 
ATOM   10062 C CD1   . PHE C 1 247 ? -21.266 20.089  -82.970  1.00 65.21  ? 247 PHE C CD1   1 
ATOM   10063 C CD2   . PHE C 1 247 ? -22.119 18.014  -82.177  1.00 63.94  ? 247 PHE C CD2   1 
ATOM   10064 C CE1   . PHE C 1 247 ? -21.407 20.626  -81.698  1.00 61.04  ? 247 PHE C CE1   1 
ATOM   10065 C CE2   . PHE C 1 247 ? -22.251 18.552  -80.906  1.00 60.78  ? 247 PHE C CE2   1 
ATOM   10066 C CZ    . PHE C 1 247 ? -21.891 19.857  -80.668  1.00 58.64  ? 247 PHE C CZ    1 
ATOM   10067 N N     . GLU C 1 248 ? -22.250 18.096  -87.906  1.00 67.37  ? 248 GLU C N     1 
ATOM   10068 C CA    . GLU C 1 248 ? -22.373 17.433  -89.208  1.00 63.22  ? 248 GLU C CA    1 
ATOM   10069 C C     . GLU C 1 248 ? -21.276 16.404  -89.455  1.00 61.19  ? 248 GLU C C     1 
ATOM   10070 O O     . GLU C 1 248 ? -21.535 15.347  -90.040  1.00 62.42  ? 248 GLU C O     1 
ATOM   10071 C CB    . GLU C 1 248 ? -22.298 18.414  -90.379  1.00 73.27  ? 248 GLU C CB    1 
ATOM   10072 C CG    . GLU C 1 248 ? -23.567 19.233  -90.568  1.00 94.25  ? 248 GLU C CG    1 
ATOM   10073 C CD    . GLU C 1 248 ? -23.942 19.558  -92.005  1.00 105.47 ? 248 GLU C CD    1 
ATOM   10074 O OE1   . GLU C 1 248 ? -23.321 18.976  -92.937  1.00 93.62  ? 248 GLU C OE1   1 
ATOM   10075 O OE2   . GLU C 1 248 ? -24.866 20.387  -92.189  1.00 117.21 ? 248 GLU C OE2   1 
ATOM   10076 N N     . ASN C 1 249 ? -20.056 16.718  -89.010  1.00 58.00  ? 249 ASN C N     1 
ATOM   10077 C CA    . ASN C 1 249 ? -18.884 15.955  -89.404  1.00 62.53  ? 249 ASN C CA    1 
ATOM   10078 C C     . ASN C 1 249 ? -18.417 15.039  -88.278  1.00 66.76  ? 249 ASN C C     1 
ATOM   10079 O O     . ASN C 1 249 ? -18.438 15.415  -87.107  1.00 84.52  ? 249 ASN C O     1 
ATOM   10080 C CB    . ASN C 1 249 ? -17.765 16.895  -89.846  1.00 63.83  ? 249 ASN C CB    1 
ATOM   10081 C CG    . ASN C 1 249 ? -18.232 17.780  -90.979  1.00 67.62  ? 249 ASN C CG    1 
ATOM   10082 O OD1   . ASN C 1 249 ? -18.296 17.341  -92.129  1.00 69.84  ? 249 ASN C OD1   1 
ATOM   10083 N ND2   . ASN C 1 249 ? -18.600 19.010  -90.651  1.00 59.29  ? 249 ASN C ND2   1 
ATOM   10084 N N     . GLU C 1 250 ? -17.942 13.851  -88.654  1.00 62.53  ? 250 GLU C N     1 
ATOM   10085 C CA    . GLU C 1 250 ? -17.433 12.911  -87.677  1.00 64.72  ? 250 GLU C CA    1 
ATOM   10086 C C     . GLU C 1 250 ? -16.236 13.505  -86.928  1.00 71.13  ? 250 GLU C C     1 
ATOM   10087 O O     . GLU C 1 250 ? -16.054 13.184  -85.753  1.00 71.74  ? 250 GLU C O     1 
ATOM   10088 C CB    . GLU C 1 250 ? -17.143 11.549  -88.310  1.00 74.47  ? 250 GLU C CB    1 
ATOM   10089 C CG    . GLU C 1 250 ? -16.422 11.579  -89.651  1.00 87.09  ? 250 GLU C CG    1 
ATOM   10090 C CD    . GLU C 1 250 ? -15.959 10.196  -90.088  1.00 88.65  ? 250 GLU C CD    1 
ATOM   10091 O OE1   . GLU C 1 250 ? -16.733 9.239   -89.894  1.00 80.52  ? 250 GLU C OE1   1 
ATOM   10092 O OE2   . GLU C 1 250 ? -14.832 10.071  -90.608  1.00 89.59  ? 250 GLU C OE2   1 
ATOM   10093 N N     . ASP C 1 251 ? -15.448 14.399  -87.557  1.00 64.65  ? 251 ASP C N     1 
ATOM   10094 C CA    . ASP C 1 251 ? -14.248 14.910  -86.906  1.00 65.51  ? 251 ASP C CA    1 
ATOM   10095 C C     . ASP C 1 251 ? -14.586 15.998  -85.872  1.00 68.24  ? 251 ASP C C     1 
ATOM   10096 O O     . ASP C 1 251 ? -13.717 16.458  -85.129  1.00 64.80  ? 251 ASP C O     1 
ATOM   10097 C CB    . ASP C 1 251 ? -13.219 15.424  -87.922  1.00 73.15  ? 251 ASP C CB    1 
ATOM   10098 C CG    . ASP C 1 251 ? -12.586 14.391  -88.853  1.00 77.86  ? 251 ASP C CG    1 
ATOM   10099 O OD1   . ASP C 1 251 ? -12.097 13.338  -88.370  1.00 59.17  ? 251 ASP C OD1   1 
ATOM   10100 O OD2   . ASP C 1 251 ? -12.521 14.684  -90.064  1.00 92.37  ? 251 ASP C OD2   1 
ATOM   10101 N N     . ASP C 1 252 ? -15.849 16.429  -85.822  1.00 65.08  ? 252 ASP C N     1 
ATOM   10102 C CA    . ASP C 1 252 ? -16.261 17.488  -84.916  1.00 64.28  ? 252 ASP C CA    1 
ATOM   10103 C C     . ASP C 1 252 ? -16.179 17.023  -83.461  1.00 60.96  ? 252 ASP C C     1 
ATOM   10104 O O     . ASP C 1 252 ? -16.189 17.859  -82.556  1.00 49.16  ? 252 ASP C O     1 
ATOM   10105 C CB    . ASP C 1 252 ? -17.698 17.930  -85.206  1.00 66.41  ? 252 ASP C CB    1 
ATOM   10106 C CG    . ASP C 1 252 ? -17.896 18.787  -86.445  1.00 64.40  ? 252 ASP C CG    1 
ATOM   10107 O OD1   . ASP C 1 252 ? -16.937 19.470  -86.851  1.00 61.21  ? 252 ASP C OD1   1 
ATOM   10108 O OD2   . ASP C 1 252 ? -19.039 18.786  -86.971  1.00 64.41  ? 252 ASP C OD2   1 
ATOM   10109 N N     . ILE C 1 253 ? -16.136 15.697  -83.238  1.00 54.19  ? 253 ILE C N     1 
ATOM   10110 C CA    . ILE C 1 253 ? -16.096 15.165  -81.883  1.00 58.69  ? 253 ILE C CA    1 
ATOM   10111 C C     . ILE C 1 253 ? -14.813 15.635  -81.194  1.00 58.07  ? 253 ILE C C     1 
ATOM   10112 O O     . ILE C 1 253 ? -14.812 15.830  -79.982  1.00 61.50  ? 253 ILE C O     1 
ATOM   10113 C CB    . ILE C 1 253 ? -16.264 13.624  -81.827  1.00 59.56  ? 253 ILE C CB    1 
ATOM   10114 C CG1   . ILE C 1 253 ? -16.509 13.125  -80.399  1.00 59.03  ? 253 ILE C CG1   1 
ATOM   10115 C CG2   . ILE C 1 253 ? -15.084 12.884  -82.438  1.00 60.82  ? 253 ILE C CG2   1 
ATOM   10116 C CD1   . ILE C 1 253 ? -17.897 13.378  -79.868  1.00 62.90  ? 253 ILE C CD1   1 
ATOM   10117 N N     . GLU C 1 254 ? -13.723 15.815  -81.946  1.00 58.41  ? 254 GLU C N     1 
ATOM   10118 C CA    . GLU C 1 254 ? -12.479 16.258  -81.335  1.00 63.29  ? 254 GLU C CA    1 
ATOM   10119 C C     . GLU C 1 254 ? -12.686 17.625  -80.683  1.00 62.45  ? 254 GLU C C     1 
ATOM   10120 O O     . GLU C 1 254 ? -12.437 17.787  -79.490  1.00 63.52  ? 254 GLU C O     1 
ATOM   10121 C CB    . GLU C 1 254 ? -11.328 16.279  -82.337  1.00 60.28  ? 254 GLU C CB    1 
ATOM   10122 C CG    . GLU C 1 254 ? -10.055 16.932  -81.816  1.00 62.54  ? 254 GLU C CG    1 
ATOM   10123 C CD    . GLU C 1 254 ? -8.789  16.624  -82.610  1.00 68.72  ? 254 GLU C CD    1 
ATOM   10124 O OE1   . GLU C 1 254 ? -8.896  16.181  -83.781  1.00 68.10  ? 254 GLU C OE1   1 
ATOM   10125 O OE2   . GLU C 1 254 ? -7.685  16.780  -82.039  1.00 71.09  ? 254 GLU C OE2   1 
ATOM   10126 N N     . THR C 1 255 ? -13.175 18.593  -81.451  1.00 52.75  ? 255 THR C N     1 
ATOM   10127 C CA    . THR C 1 255 ? -13.315 19.941  -80.926  1.00 53.22  ? 255 THR C CA    1 
ATOM   10128 C C     . THR C 1 255 ? -14.415 19.998  -79.861  1.00 52.71  ? 255 THR C C     1 
ATOM   10129 O O     . THR C 1 255 ? -14.343 20.832  -78.960  1.00 55.10  ? 255 THR C O     1 
ATOM   10130 C CB    . THR C 1 255 ? -13.590 20.955  -82.046  1.00 48.83  ? 255 THR C CB    1 
ATOM   10131 O OG1   . THR C 1 255 ? -13.446 22.277  -81.526  1.00 52.19  ? 255 THR C OG1   1 
ATOM   10132 C CG2   . THR C 1 255 ? -14.982 20.841  -82.622  1.00 56.48  ? 255 THR C CG2   1 
ATOM   10133 N N     . VAL C 1 256 ? -15.429 19.124  -79.972  1.00 51.09  ? 256 VAL C N     1 
ATOM   10134 C CA    . VAL C 1 256 ? -16.584 19.153  -79.079  1.00 54.19  ? 256 VAL C CA    1 
ATOM   10135 C C     . VAL C 1 256 ? -16.184 18.680  -77.675  1.00 49.93  ? 256 VAL C C     1 
ATOM   10136 O O     . VAL C 1 256 ? -16.600 19.262  -76.671  1.00 40.24  ? 256 VAL C O     1 
ATOM   10137 C CB    . VAL C 1 256 ? -17.757 18.330  -79.652  1.00 54.95  ? 256 VAL C CB    1 
ATOM   10138 C CG1   . VAL C 1 256 ? -18.653 17.717  -78.578  1.00 58.12  ? 256 VAL C CG1   1 
ATOM   10139 C CG2   . VAL C 1 256 ? -18.592 19.153  -80.606  1.00 55.86  ? 256 VAL C CG2   1 
ATOM   10140 N N     . THR C 1 257 ? -15.380 17.623  -77.615  1.00 46.45  ? 257 THR C N     1 
ATOM   10141 C CA    . THR C 1 257 ? -14.868 17.153  -76.351  1.00 55.41  ? 257 THR C CA    1 
ATOM   10142 C C     . THR C 1 257 ? -14.037 18.265  -75.715  1.00 60.05  ? 257 THR C C     1 
ATOM   10143 O O     . THR C 1 257 ? -14.107 18.449  -74.502  1.00 60.43  ? 257 THR C O     1 
ATOM   10144 C CB    . THR C 1 257 ? -14.149 15.810  -76.530  1.00 64.59  ? 257 THR C CB    1 
ATOM   10145 O OG1   . THR C 1 257 ? -15.034 14.895  -77.187  1.00 62.11  ? 257 THR C OG1   1 
ATOM   10146 C CG2   . THR C 1 257 ? -13.711 15.195  -75.217  1.00 69.41  ? 257 THR C CG2   1 
ATOM   10147 N N     . GLU C 1 258 ? -13.308 19.048  -76.528  1.00 59.92  ? 258 GLU C N     1 
ATOM   10148 C CA    . GLU C 1 258 ? -12.408 20.062  -75.993  1.00 55.83  ? 258 GLU C CA    1 
ATOM   10149 C C     . GLU C 1 258 ? -13.207 21.124  -75.261  1.00 53.23  ? 258 GLU C C     1 
ATOM   10150 O O     . GLU C 1 258 ? -12.728 21.616  -74.243  1.00 61.91  ? 258 GLU C O     1 
ATOM   10151 C CB    . GLU C 1 258 ? -11.540 20.747  -77.054  1.00 53.20  ? 258 GLU C CB    1 
ATOM   10152 C CG    . GLU C 1 258 ? -10.326 19.932  -77.445  1.00 59.43  ? 258 GLU C CG    1 
ATOM   10153 C CD    . GLU C 1 258 ? -9.353  19.590  -76.328  1.00 62.47  ? 258 GLU C CD    1 
ATOM   10154 O OE1   . GLU C 1 258 ? -8.692  20.525  -75.838  1.00 58.02  ? 258 GLU C OE1   1 
ATOM   10155 O OE2   . GLU C 1 258 ? -9.238  18.385  -75.970  1.00 60.21  ? 258 GLU C OE2   1 
ATOM   10156 N N     . ARG C 1 259 ? -14.377 21.482  -75.809  1.00 52.76  ? 259 ARG C N     1 
ATOM   10157 C CA    . ARG C 1 259 ? -15.214 22.550  -75.265  1.00 54.81  ? 259 ARG C CA    1 
ATOM   10158 C C     . ARG C 1 259 ? -16.038 22.079  -74.070  1.00 54.61  ? 259 ARG C C     1 
ATOM   10159 O O     . ARG C 1 259 ? -16.410 22.887  -73.221  1.00 66.23  ? 259 ARG C O     1 
ATOM   10160 C CB    . ARG C 1 259 ? -16.178 23.080  -76.326  1.00 48.82  ? 259 ARG C CB    1 
ATOM   10161 C CG    . ARG C 1 259 ? -15.467 23.845  -77.429  1.00 59.08  ? 259 ARG C CG    1 
ATOM   10162 C CD    . ARG C 1 259 ? -16.006 23.462  -78.800  1.00 71.57  ? 259 ARG C CD    1 
ATOM   10163 N NE    . ARG C 1 259 ? -15.133 23.907  -79.879  1.00 65.01  ? 259 ARG C NE    1 
ATOM   10164 C CZ    . ARG C 1 259 ? -15.355 24.973  -80.631  1.00 60.89  ? 259 ARG C CZ    1 
ATOM   10165 N NH1   . ARG C 1 259 ? -16.341 25.810  -80.363  1.00 65.10  ? 259 ARG C NH1   1 
ATOM   10166 N NH2   . ARG C 1 259 ? -14.570 25.205  -81.656  1.00 64.56  ? 259 ARG C NH2   1 
ATOM   10167 N N     . LEU C 1 260 ? -16.371 20.788  -74.054  1.00 53.04  ? 260 LEU C N     1 
ATOM   10168 C CA    . LEU C 1 260 ? -17.151 20.206  -72.979  1.00 53.28  ? 260 LEU C CA    1 
ATOM   10169 C C     . LEU C 1 260 ? -16.327 20.192  -71.692  1.00 52.81  ? 260 LEU C C     1 
ATOM   10170 O O     . LEU C 1 260 ? -16.879 20.455  -70.634  1.00 62.95  ? 260 LEU C O     1 
ATOM   10171 C CB    . LEU C 1 260 ? -17.575 18.792  -73.383  1.00 49.39  ? 260 LEU C CB    1 
ATOM   10172 C CG    . LEU C 1 260 ? -18.818 18.714  -74.267  1.00 52.55  ? 260 LEU C CG    1 
ATOM   10173 C CD1   . LEU C 1 260 ? -19.020 17.307  -74.793  1.00 52.02  ? 260 LEU C CD1   1 
ATOM   10174 C CD2   . LEU C 1 260 ? -20.057 19.168  -73.510  1.00 51.46  ? 260 LEU C CD2   1 
ATOM   10175 N N     . ARG C 1 261 ? -15.017 19.946  -71.799  1.00 46.37  ? 261 ARG C N     1 
ATOM   10176 C CA    . ARG C 1 261 ? -14.141 19.808  -70.646  1.00 51.82  ? 261 ARG C CA    1 
ATOM   10177 C C     . ARG C 1 261 ? -14.359 20.910  -69.605  1.00 54.62  ? 261 ARG C C     1 
ATOM   10178 O O     . ARG C 1 261 ? -14.752 20.616  -68.493  1.00 51.98  ? 261 ARG C O     1 
ATOM   10179 C CB    . ARG C 1 261 ? -12.664 19.761  -71.039  1.00 50.78  ? 261 ARG C CB    1 
ATOM   10180 C CG    . ARG C 1 261 ? -11.757 19.428  -69.863  1.00 56.19  ? 261 ARG C CG    1 
ATOM   10181 C CD    . ARG C 1 261 ? -10.314 19.195  -70.251  1.00 54.08  ? 261 ARG C CD    1 
ATOM   10182 N NE    . ARG C 1 261 ? -9.824  20.319  -71.041  1.00 58.56  ? 261 ARG C NE    1 
ATOM   10183 C CZ    . ARG C 1 261 ? -9.455  20.267  -72.319  1.00 57.44  ? 261 ARG C CZ    1 
ATOM   10184 N NH1   . ARG C 1 261 ? -9.563  19.145  -73.009  1.00 64.55  ? 261 ARG C NH1   1 
ATOM   10185 N NH2   . ARG C 1 261 ? -8.995  21.352  -72.916  1.00 55.54  ? 261 ARG C NH2   1 
ATOM   10186 N N     . PRO C 1 262 ? -14.076 22.203  -69.852  1.00 59.17  ? 262 PRO C N     1 
ATOM   10187 C CA    . PRO C 1 262 ? -14.267 23.200  -68.800  1.00 60.83  ? 262 PRO C CA    1 
ATOM   10188 C C     . PRO C 1 262 ? -15.716 23.273  -68.317  1.00 54.32  ? 262 PRO C C     1 
ATOM   10189 O O     . PRO C 1 262 ? -15.942 23.457  -67.124  1.00 56.04  ? 262 PRO C O     1 
ATOM   10190 C CB    . PRO C 1 262 ? -13.793 24.523  -69.432  1.00 59.52  ? 262 PRO C CB    1 
ATOM   10191 C CG    . PRO C 1 262 ? -13.883 24.254  -70.925  1.00 61.47  ? 262 PRO C CG    1 
ATOM   10192 C CD    . PRO C 1 262 ? -13.550 22.787  -71.094  1.00 58.10  ? 262 PRO C CD    1 
ATOM   10193 N N     . LEU C 1 263 ? -16.682 23.151  -69.233  1.00 52.52  ? 263 LEU C N     1 
ATOM   10194 C CA    . LEU C 1 263 ? -18.087 23.316  -68.880  1.00 53.62  ? 263 LEU C CA    1 
ATOM   10195 C C     . LEU C 1 263 ? -18.509 22.245  -67.876  1.00 54.18  ? 263 LEU C C     1 
ATOM   10196 O O     . LEU C 1 263 ? -19.404 22.449  -67.051  1.00 54.14  ? 263 LEU C O     1 
ATOM   10197 C CB    . LEU C 1 263 ? -18.951 23.197  -70.137  1.00 52.62  ? 263 LEU C CB    1 
ATOM   10198 C CG    . LEU C 1 263 ? -18.933 24.415  -71.056  1.00 56.03  ? 263 LEU C CG    1 
ATOM   10199 C CD1   . LEU C 1 263 ? -19.898 24.235  -72.235  1.00 51.68  ? 263 LEU C CD1   1 
ATOM   10200 C CD2   . LEU C 1 263 ? -19.249 25.683  -70.263  1.00 52.35  ? 263 LEU C CD2   1 
ATOM   10201 N N     . LYS C 1 264 ? -17.862 21.092  -67.987  1.00 44.30  ? 264 LYS C N     1 
ATOM   10202 C CA    . LYS C 1 264 ? -18.216 19.927  -67.207  1.00 52.59  ? 264 LYS C CA    1 
ATOM   10203 C C     . LYS C 1 264 ? -17.442 19.958  -65.883  1.00 56.29  ? 264 LYS C C     1 
ATOM   10204 O O     . LYS C 1 264 ? -18.016 19.724  -64.822  1.00 54.26  ? 264 LYS C O     1 
ATOM   10205 C CB    . LYS C 1 264 ? -17.948 18.706  -68.093  1.00 56.72  ? 264 LYS C CB    1 
ATOM   10206 C CG    . LYS C 1 264 ? -18.725 17.452  -67.747  1.00 61.66  ? 264 LYS C CG    1 
ATOM   10207 C CD    . LYS C 1 264 ? -20.169 17.540  -68.052  1.00 63.54  ? 264 LYS C CD    1 
ATOM   10208 C CE    . LYS C 1 264 ? -20.928 16.446  -67.343  1.00 65.01  ? 264 LYS C CE    1 
ATOM   10209 N NZ    . LYS C 1 264 ? -21.019 16.710  -65.892  1.00 60.26  ? 264 LYS C NZ    1 
ATOM   10210 N N     . VAL C 1 265 ? -16.158 20.342  -65.954  1.00 57.87  ? 265 VAL C N     1 
ATOM   10211 C CA    . VAL C 1 265 ? -15.276 20.368  -64.809  1.00 53.23  ? 265 VAL C CA    1 
ATOM   10212 C C     . VAL C 1 265 ? -15.748 21.402  -63.800  1.00 50.34  ? 265 VAL C C     1 
ATOM   10213 O O     . VAL C 1 265 ? -15.747 21.123  -62.607  1.00 52.80  ? 265 VAL C O     1 
ATOM   10214 C CB    . VAL C 1 265 ? -13.818 20.615  -65.207  1.00 53.72  ? 265 VAL C CB    1 
ATOM   10215 C CG1   . VAL C 1 265 ? -12.979 20.939  -63.978  1.00 59.52  ? 265 VAL C CG1   1 
ATOM   10216 C CG2   . VAL C 1 265 ? -13.243 19.424  -65.951  1.00 50.74  ? 265 VAL C CG2   1 
ATOM   10217 N N     . ALA C 1 266 ? -16.203 22.550  -64.283  1.00 49.22  ? 266 ALA C N     1 
ATOM   10218 C CA    . ALA C 1 266 ? -16.682 23.607  -63.405  1.00 46.96  ? 266 ALA C CA    1 
ATOM   10219 C C     . ALA C 1 266 ? -18.156 23.428  -63.078  1.00 48.43  ? 266 ALA C C     1 
ATOM   10220 O O     . ALA C 1 266 ? -18.744 24.315  -62.476  1.00 58.36  ? 266 ALA C O     1 
ATOM   10221 C CB    . ALA C 1 266 ? -16.477 24.962  -64.037  1.00 45.45  ? 266 ALA C CB    1 
ATOM   10222 N N     . GLY C 1 267 ? -18.772 22.335  -63.520  1.00 50.57  ? 267 GLY C N     1 
ATOM   10223 C CA    . GLY C 1 267 ? -20.168 22.076  -63.190  1.00 49.53  ? 267 GLY C CA    1 
ATOM   10224 C C     . GLY C 1 267 ? -21.175 23.017  -63.855  1.00 48.76  ? 267 GLY C C     1 
ATOM   10225 O O     . GLY C 1 267 ? -22.268 23.137  -63.340  1.00 50.09  ? 267 GLY C O     1 
ATOM   10226 N N     . VAL C 1 268 ? -20.865 23.584  -65.039  1.00 53.64  ? 268 VAL C N     1 
ATOM   10227 C CA    . VAL C 1 268 ? -21.801 24.413  -65.801  1.00 55.39  ? 268 VAL C CA    1 
ATOM   10228 C C     . VAL C 1 268 ? -22.896 23.549  -66.444  1.00 52.99  ? 268 VAL C C     1 
ATOM   10229 O O     . VAL C 1 268 ? -24.082 23.836  -66.343  1.00 57.35  ? 268 VAL C O     1 
ATOM   10230 C CB    . VAL C 1 268 ? -21.052 25.260  -66.850  1.00 52.46  ? 268 VAL C CB    1 
ATOM   10231 C CG1   . VAL C 1 268 ? -22.003 25.980  -67.785  1.00 50.72  ? 268 VAL C CG1   1 
ATOM   10232 C CG2   . VAL C 1 268 ? -20.100 26.251  -66.186  1.00 53.64  ? 268 VAL C CG2   1 
ATOM   10233 N N     . ILE C 1 269 ? -22.502 22.485  -67.131  1.00 46.99  ? 269 ILE C N     1 
ATOM   10234 C CA    . ILE C 1 269 ? -23.423 21.403  -67.404  1.00 47.47  ? 269 ILE C CA    1 
ATOM   10235 C C     . ILE C 1 269 ? -23.610 20.592  -66.122  1.00 48.18  ? 269 ILE C C     1 
ATOM   10236 O O     . ILE C 1 269 ? -22.634 20.114  -65.557  1.00 52.22  ? 269 ILE C O     1 
ATOM   10237 C CB    . ILE C 1 269 ? -22.869 20.534  -68.538  1.00 47.66  ? 269 ILE C CB    1 
ATOM   10238 C CG1   . ILE C 1 269 ? -22.792 21.315  -69.843  1.00 49.30  ? 269 ILE C CG1   1 
ATOM   10239 C CG2   . ILE C 1 269 ? -23.679 19.260  -68.694  1.00 48.66  ? 269 ILE C CG2   1 
ATOM   10240 C CD1   . ILE C 1 269 ? -22.028 20.568  -70.882  1.00 52.15  ? 269 ILE C CD1   1 
ATOM   10241 N N     . GLN C 1 270 ? -24.865 20.367  -65.727  1.00 50.22  ? 270 GLN C N     1 
ATOM   10242 C CA    . GLN C 1 270 ? -25.201 19.895  -64.388  1.00 56.35  ? 270 GLN C CA    1 
ATOM   10243 C C     . GLN C 1 270 ? -25.412 18.373  -64.309  1.00 59.77  ? 270 GLN C C     1 
ATOM   10244 O O     . GLN C 1 270 ? -25.339 17.791  -63.219  1.00 55.94  ? 270 GLN C O     1 
ATOM   10245 C CB    . GLN C 1 270 ? -26.470 20.611  -63.921  1.00 51.87  ? 270 GLN C CB    1 
ATOM   10246 C CG    . GLN C 1 270 ? -26.350 22.127  -63.913  1.00 49.79  ? 270 GLN C CG    1 
ATOM   10247 C CD    . GLN C 1 270 ? -27.672 22.743  -64.299  1.00 55.29  ? 270 GLN C CD    1 
ATOM   10248 O OE1   . GLN C 1 270 ? -28.094 22.698  -65.456  1.00 67.34  ? 270 GLN C OE1   1 
ATOM   10249 N NE2   . GLN C 1 270 ? -28.358 23.313  -63.328  1.00 52.38  ? 270 GLN C NE2   1 
ATOM   10250 N N     . ASN C 1 271 ? -25.719 17.729  -65.446  1.00 58.14  ? 271 ASN C N     1 
ATOM   10251 C CA    . ASN C 1 271 ? -25.871 16.283  -65.495  1.00 53.27  ? 271 ASN C CA    1 
ATOM   10252 C C     . ASN C 1 271 ? -24.698 15.670  -66.260  1.00 53.41  ? 271 ASN C C     1 
ATOM   10253 O O     . ASN C 1 271 ? -23.689 16.332  -66.501  1.00 45.71  ? 271 ASN C O     1 
ATOM   10254 C CB    . ASN C 1 271 ? -27.223 15.887  -66.093  1.00 55.51  ? 271 ASN C CB    1 
ATOM   10255 C CG    . ASN C 1 271 ? -27.424 16.382  -67.513  1.00 53.01  ? 271 ASN C CG    1 
ATOM   10256 O OD1   . ASN C 1 271 ? -26.736 17.293  -67.966  1.00 49.33  ? 271 ASN C OD1   1 
ATOM   10257 N ND2   . ASN C 1 271 ? -28.393 15.807  -68.205  1.00 49.26  ? 271 ASN C ND2   1 
ATOM   10258 N N     . GLY C 1 272 ? -24.811 14.376  -66.589  1.00 58.62  ? 272 GLY C N     1 
ATOM   10259 C CA    . GLY C 1 272 ? -23.862 13.753  -67.491  1.00 62.09  ? 272 GLY C CA    1 
ATOM   10260 C C     . GLY C 1 272 ? -24.070 14.266  -68.912  1.00 61.99  ? 272 GLY C C     1 
ATOM   10261 O O     . GLY C 1 272 ? -25.208 14.462  -69.341  1.00 60.01  ? 272 GLY C O     1 
ATOM   10262 N N     . ALA C 1 273 ? -22.956 14.518  -69.602  1.00 63.93  ? 273 ALA C N     1 
ATOM   10263 C CA    . ALA C 1 273 ? -22.960 14.969  -70.986  1.00 67.03  ? 273 ALA C CA    1 
ATOM   10264 C C     . ALA C 1 273 ? -22.835 13.763  -71.915  1.00 70.08  ? 273 ALA C C     1 
ATOM   10265 O O     . ALA C 1 273 ? -21.810 13.050  -71.887  1.00 55.85  ? 273 ALA C O     1 
ATOM   10266 C CB    . ALA C 1 273 ? -21.820 15.939  -71.216  1.00 65.89  ? 273 ALA C CB    1 
ATOM   10267 N N     . THR C 1 274 ? -23.885 13.570  -72.737  1.00 68.55  ? 274 THR C N     1 
ATOM   10268 C CA    . THR C 1 274 ? -23.923 12.499  -73.720  1.00 65.29  ? 274 THR C CA    1 
ATOM   10269 C C     . THR C 1 274 ? -23.842 13.071  -75.139  1.00 59.00  ? 274 THR C C     1 
ATOM   10270 O O     . THR C 1 274 ? -24.630 13.934  -75.529  1.00 62.36  ? 274 THR C O     1 
ATOM   10271 C CB    . THR C 1 274 ? -25.151 11.622  -73.482  1.00 69.04  ? 274 THR C CB    1 
ATOM   10272 O OG1   . THR C 1 274 ? -26.263 12.508  -73.416  1.00 84.96  ? 274 THR C OG1   1 
ATOM   10273 C CG2   . THR C 1 274 ? -25.054 10.820  -72.205  1.00 71.92  ? 274 THR C CG2   1 
ATOM   10274 N N     . VAL C 1 275 ? -22.854 12.583  -75.894  1.00 54.72  ? 275 VAL C N     1 
ATOM   10275 C CA    . VAL C 1 275 ? -22.710 12.876  -77.309  1.00 53.53  ? 275 VAL C CA    1 
ATOM   10276 C C     . VAL C 1 275 ? -22.738 11.556  -78.067  1.00 57.68  ? 275 VAL C C     1 
ATOM   10277 O O     . VAL C 1 275 ? -21.781 10.776  -78.004  1.00 53.10  ? 275 VAL C O     1 
ATOM   10278 C CB    . VAL C 1 275 ? -21.406 13.629  -77.583  1.00 51.69  ? 275 VAL C CB    1 
ATOM   10279 C CG1   . VAL C 1 275 ? -21.367 14.151  -79.005  1.00 51.57  ? 275 VAL C CG1   1 
ATOM   10280 C CG2   . VAL C 1 275 ? -21.206 14.752  -76.580  1.00 56.57  ? 275 VAL C CG2   1 
ATOM   10281 N N     . ARG C 1 276 ? -23.862 11.320  -78.755  1.00 58.92  ? 276 ARG C N     1 
ATOM   10282 C CA    . ARG C 1 276 ? -24.199 10.018  -79.312  1.00 59.16  ? 276 ARG C CA    1 
ATOM   10283 C C     . ARG C 1 276 ? -24.023 10.075  -80.833  1.00 58.20  ? 276 ARG C C     1 
ATOM   10284 O O     . ARG C 1 276 ? -24.300 11.115  -81.456  1.00 54.49  ? 276 ARG C O     1 
ATOM   10285 C CB    . ARG C 1 276 ? -25.625 9.665   -78.858  1.00 68.62  ? 276 ARG C CB    1 
ATOM   10286 C CG    . ARG C 1 276 ? -25.875 9.918   -77.371  1.00 79.56  ? 276 ARG C CG    1 
ATOM   10287 C CD    . ARG C 1 276 ? -27.301 9.818   -76.850  1.00 87.83  ? 276 ARG C CD    1 
ATOM   10288 N NE    . ARG C 1 276 ? -27.672 8.432   -76.600  1.00 87.50  ? 276 ARG C NE    1 
ATOM   10289 C CZ    . ARG C 1 276 ? -27.754 7.869   -75.398  1.00 89.08  ? 276 ARG C CZ    1 
ATOM   10290 N NH1   . ARG C 1 276 ? -27.692 8.632   -74.320  1.00 84.78  ? 276 ARG C NH1   1 
ATOM   10291 N NH2   . ARG C 1 276 ? -27.897 6.551   -75.285  1.00 85.22  ? 276 ARG C NH2   1 
ATOM   10292 N N     . SER C 1 277 ? -23.546 8.954   -81.414  1.00 63.29  ? 277 SER C N     1 
ATOM   10293 C CA    . SER C 1 277 ? -23.279 8.833   -82.852  1.00 60.40  ? 277 SER C CA    1 
ATOM   10294 C C     . SER C 1 277 ? -24.580 8.685   -83.639  1.00 57.28  ? 277 SER C C     1 
ATOM   10295 O O     . SER C 1 277 ? -25.617 8.303   -83.100  1.00 53.23  ? 277 SER C O     1 
ATOM   10296 C CB    . SER C 1 277 ? -22.361 7.670   -83.161  1.00 57.88  ? 277 SER C CB    1 
ATOM   10297 O OG    . SER C 1 277 ? -23.045 6.436   -82.979  1.00 54.11  ? 277 SER C OG    1 
ATOM   10298 N N     . LEU C 1 278 ? -24.496 8.961   -84.940  1.00 61.45  ? 278 LEU C N     1 
ATOM   10299 C CA    . LEU C 1 278 ? -25.664 9.023   -85.803  1.00 62.31  ? 278 LEU C CA    1 
ATOM   10300 C C     . LEU C 1 278 ? -26.526 7.763   -85.699  1.00 57.83  ? 278 LEU C C     1 
ATOM   10301 O O     . LEU C 1 278 ? -27.736 7.846   -85.517  1.00 52.51  ? 278 LEU C O     1 
ATOM   10302 C CB    . LEU C 1 278 ? -25.182 9.196   -87.237  1.00 61.93  ? 278 LEU C CB    1 
ATOM   10303 C CG    . LEU C 1 278 ? -26.282 9.030   -88.279  1.00 70.60  ? 278 LEU C CG    1 
ATOM   10304 C CD1   . LEU C 1 278 ? -27.297 10.164  -88.161  1.00 73.67  ? 278 LEU C CD1   1 
ATOM   10305 C CD2   . LEU C 1 278 ? -25.683 8.948   -89.675  1.00 67.21  ? 278 LEU C CD2   1 
ATOM   10306 N N     . VAL C 1 279 ? -25.895 6.598   -85.838  1.00 59.59  ? 279 VAL C N     1 
ATOM   10307 C CA    . VAL C 1 279 ? -26.631 5.352   -85.949  1.00 57.97  ? 279 VAL C CA    1 
ATOM   10308 C C     . VAL C 1 279 ? -27.315 5.044   -84.627  1.00 61.62  ? 279 VAL C C     1 
ATOM   10309 O O     . VAL C 1 279 ? -28.438 4.554   -84.619  1.00 77.94  ? 279 VAL C O     1 
ATOM   10310 C CB    . VAL C 1 279 ? -25.725 4.179   -86.354  1.00 55.01  ? 279 VAL C CB    1 
ATOM   10311 C CG1   . VAL C 1 279 ? -26.482 2.867   -86.364  1.00 48.93  ? 279 VAL C CG1   1 
ATOM   10312 C CG2   . VAL C 1 279 ? -25.067 4.422   -87.698  1.00 59.32  ? 279 VAL C CG2   1 
ATOM   10313 N N     . LEU C 1 280 ? -26.623 5.280   -83.513  1.00 68.79  ? 280 LEU C N     1 
ATOM   10314 C CA    . LEU C 1 280 ? -27.172 4.910   -82.221  1.00 67.30  ? 280 LEU C CA    1 
ATOM   10315 C C     . LEU C 1 280 ? -28.430 5.723   -81.947  1.00 65.84  ? 280 LEU C C     1 
ATOM   10316 O O     . LEU C 1 280 ? -29.431 5.161   -81.520  1.00 65.06  ? 280 LEU C O     1 
ATOM   10317 C CB    . LEU C 1 280 ? -26.142 5.134   -81.117  1.00 63.55  ? 280 LEU C CB    1 
ATOM   10318 C CG    . LEU C 1 280 ? -26.636 4.830   -79.706  1.00 60.43  ? 280 LEU C CG    1 
ATOM   10319 C CD1   . LEU C 1 280 ? -27.131 3.394   -79.599  1.00 58.55  ? 280 LEU C CD1   1 
ATOM   10320 C CD2   . LEU C 1 280 ? -25.523 5.083   -78.698  1.00 66.21  ? 280 LEU C CD2   1 
ATOM   10321 N N     . ASP C 1 281 ? -28.374 7.032   -82.215  1.00 61.75  ? 281 ASP C N     1 
ATOM   10322 C CA    . ASP C 1 281 ? -29.527 7.889   -81.989  1.00 65.89  ? 281 ASP C CA    1 
ATOM   10323 C C     . ASP C 1 281 ? -30.599 7.538   -83.016  1.00 65.21  ? 281 ASP C C     1 
ATOM   10324 O O     . ASP C 1 281 ? -31.776 7.510   -82.686  1.00 79.03  ? 281 ASP C O     1 
ATOM   10325 C CB    . ASP C 1 281 ? -29.139 9.378   -81.926  1.00 74.58  ? 281 ASP C CB    1 
ATOM   10326 C CG    . ASP C 1 281 ? -28.745 9.887   -80.532  1.00 87.80  ? 281 ASP C CG    1 
ATOM   10327 O OD1   . ASP C 1 281 ? -28.820 9.087   -79.554  1.00 84.76  ? 281 ASP C OD1   1 
ATOM   10328 O OD2   . ASP C 1 281 ? -28.363 11.090  -80.407  1.00 85.78  ? 281 ASP C OD2   1 
ATOM   10329 N N     . ALA C 1 282 ? -30.197 7.218   -84.248  1.00 63.96  ? 282 ALA C N     1 
ATOM   10330 C CA    . ALA C 1 282 ? -31.166 6.897   -85.281  1.00 57.69  ? 282 ALA C CA    1 
ATOM   10331 C C     . ALA C 1 282 ? -31.924 5.618   -84.954  1.00 52.59  ? 282 ALA C C     1 
ATOM   10332 O O     . ALA C 1 282 ? -33.092 5.500   -85.283  1.00 52.62  ? 282 ALA C O     1 
ATOM   10333 C CB    . ALA C 1 282 ? -30.480 6.770   -86.605  1.00 58.51  ? 282 ALA C CB    1 
ATOM   10334 N N     . ALA C 1 283 ? -31.258 4.644   -84.336  1.00 63.22  ? 283 ALA C N     1 
ATOM   10335 C CA    . ALA C 1 283 ? -31.826 3.306   -84.209  1.00 64.65  ? 283 ALA C CA    1 
ATOM   10336 C C     . ALA C 1 283 ? -32.940 3.285   -83.174  1.00 64.76  ? 283 ALA C C     1 
ATOM   10337 O O     . ALA C 1 283 ? -33.550 2.238   -82.937  1.00 66.28  ? 283 ALA C O     1 
ATOM   10338 C CB    . ALA C 1 283 ? -30.768 2.289   -83.866  1.00 61.18  ? 283 ALA C CB    1 
ATOM   10339 N N     . ILE C 1 284 ? -33.190 4.450   -82.568  1.00 72.61  ? 284 ILE C N     1 
ATOM   10340 C CA    . ILE C 1 284 ? -34.327 4.613   -81.680  1.00 84.61  ? 284 ILE C CA    1 
ATOM   10341 C C     . ILE C 1 284 ? -35.625 4.614   -82.498  1.00 72.46  ? 284 ILE C C     1 
ATOM   10342 O O     . ILE C 1 284 ? -36.567 3.956   -82.089  1.00 77.78  ? 284 ILE C O     1 
ATOM   10343 C CB    . ILE C 1 284 ? -34.166 5.866   -80.786  1.00 90.40  ? 284 ILE C CB    1 
ATOM   10344 C CG1   . ILE C 1 284 ? -32.825 5.884   -80.042  1.00 87.20  ? 284 ILE C CG1   1 
ATOM   10345 C CG2   . ILE C 1 284 ? -35.327 5.986   -79.809  1.00 91.31  ? 284 ILE C CG2   1 
ATOM   10346 C CD1   . ILE C 1 284 ? -32.623 4.728   -79.082  1.00 90.34  ? 284 ILE C CD1   1 
ATOM   10347 N N     . THR C 1 285 ? -35.669 5.300   -83.654  1.00 73.34  ? 285 THR C N     1 
ATOM   10348 C CA    . THR C 1 285 ? -36.912 5.492   -84.400  1.00 76.37  ? 285 THR C CA    1 
ATOM   10349 C C     . THR C 1 285 ? -36.810 4.990   -85.844  1.00 74.55  ? 285 THR C C     1 
ATOM   10350 O O     . THR C 1 285 ? -37.623 5.387   -86.687  1.00 67.52  ? 285 THR C O     1 
ATOM   10351 C CB    . THR C 1 285 ? -37.368 6.963   -84.379  1.00 79.94  ? 285 THR C CB    1 
ATOM   10352 O OG1   . THR C 1 285 ? -36.454 7.801   -85.091  1.00 87.62  ? 285 THR C OG1   1 
ATOM   10353 C CG2   . THR C 1 285 ? -37.525 7.509   -82.976  1.00 86.83  ? 285 THR C CG2   1 
ATOM   10354 N N     . ARG C 1 286 ? -35.839 4.108   -86.129  1.00 72.44  ? 286 ARG C N     1 
ATOM   10355 C CA    . ARG C 1 286 ? -35.690 3.540   -87.462  1.00 68.48  ? 286 ARG C CA    1 
ATOM   10356 C C     . ARG C 1 286 ? -35.016 2.172   -87.391  1.00 69.60  ? 286 ARG C C     1 
ATOM   10357 O O     . ARG C 1 286 ? -34.529 1.760   -86.342  1.00 79.95  ? 286 ARG C O     1 
ATOM   10358 C CB    . ARG C 1 286 ? -34.868 4.473   -88.354  1.00 72.41  ? 286 ARG C CB    1 
ATOM   10359 C CG    . ARG C 1 286 ? -35.547 5.787   -88.732  1.00 78.88  ? 286 ARG C CG    1 
ATOM   10360 C CD    . ARG C 1 286 ? -36.786 5.705   -89.615  1.00 76.23  ? 286 ARG C CD    1 
ATOM   10361 N NE    . ARG C 1 286 ? -37.295 7.025   -90.010  1.00 80.23  ? 286 ARG C NE    1 
ATOM   10362 C CZ    . ARG C 1 286 ? -37.936 7.894   -89.218  1.00 66.83  ? 286 ARG C CZ    1 
ATOM   10363 N NH1   . ARG C 1 286 ? -38.273 7.567   -87.980  1.00 57.16  ? 286 ARG C NH1   1 
ATOM   10364 N NH2   . ARG C 1 286 ? -38.253 9.094   -89.679  1.00 63.57  ? 286 ARG C NH2   1 
ATOM   10365 N N     . THR C 1 287 ? -35.015 1.463   -88.526  1.00 72.67  ? 287 THR C N     1 
ATOM   10366 C CA    . THR C 1 287 ? -34.165 0.300   -88.732  1.00 77.82  ? 287 THR C CA    1 
ATOM   10367 C C     . THR C 1 287 ? -33.297 0.499   -89.975  1.00 82.30  ? 287 THR C C     1 
ATOM   10368 O O     . THR C 1 287 ? -33.540 1.399   -90.781  1.00 96.14  ? 287 THR C O     1 
ATOM   10369 C CB    . THR C 1 287 ? -34.990 -0.980  -88.866  1.00 84.45  ? 287 THR C CB    1 
ATOM   10370 O OG1   . THR C 1 287 ? -35.786 -0.818  -90.042  1.00 77.33  ? 287 THR C OG1   1 
ATOM   10371 C CG2   . THR C 1 287 ? -35.822 -1.261  -87.633  1.00 82.66  ? 287 THR C CG2   1 
ATOM   10372 N N     . LYS C 1 288 ? -32.275 -0.355  -90.115  1.00 78.18  ? 288 LYS C N     1 
ATOM   10373 C CA    . LYS C 1 288 ? -31.323 -0.264  -91.212  1.00 77.27  ? 288 LYS C CA    1 
ATOM   10374 C C     . LYS C 1 288 ? -32.033 -0.422  -92.556  1.00 76.94  ? 288 LYS C C     1 
ATOM   10375 O O     . LYS C 1 288 ? -31.754 0.315   -93.496  1.00 71.00  ? 288 LYS C O     1 
ATOM   10376 C CB    . LYS C 1 288 ? -30.239 -1.336  -91.055  1.00 76.61  ? 288 LYS C CB    1 
ATOM   10377 C CG    . LYS C 1 288 ? -29.048 -1.197  -91.993  1.00 74.98  ? 288 LYS C CG    1 
ATOM   10378 C CD    . LYS C 1 288 ? -27.900 -2.139  -91.672  1.00 81.99  ? 288 LYS C CD    1 
ATOM   10379 C CE    . LYS C 1 288 ? -28.288 -3.600  -91.647  1.00 90.12  ? 288 LYS C CE    1 
ATOM   10380 N NZ    . LYS C 1 288 ? -27.087 -4.466  -91.702  1.00 98.45  ? 288 LYS C NZ    1 
ATOM   10381 N N     . SER C 1 289 ? -32.968 -1.379  -92.628  1.00 82.42  ? 289 SER C N     1 
ATOM   10382 C CA    . SER C 1 289 ? -33.639 -1.741  -93.869  1.00 83.59  ? 289 SER C CA    1 
ATOM   10383 C C     . SER C 1 289 ? -34.385 -0.561  -94.508  1.00 85.44  ? 289 SER C C     1 
ATOM   10384 O O     . SER C 1 289 ? -34.583 -0.569  -95.726  1.00 84.90  ? 289 SER C O     1 
ATOM   10385 C CB    . SER C 1 289 ? -34.573 -2.899  -93.639  1.00 81.55  ? 289 SER C CB    1 
ATOM   10386 O OG    . SER C 1 289 ? -35.672 -2.488  -92.841  1.00 89.63  ? 289 SER C OG    1 
ATOM   10387 N N     . GLN C 1 290 ? -34.790 0.447   -93.713  1.00 69.24  ? 290 GLN C N     1 
ATOM   10388 C CA    . GLN C 1 290 ? -35.538 1.577   -94.246  1.00 67.34  ? 290 GLN C CA    1 
ATOM   10389 C C     . GLN C 1 290 ? -34.614 2.569   -94.942  1.00 71.61  ? 290 GLN C C     1 
ATOM   10390 O O     . GLN C 1 290 ? -35.117 3.573   -95.447  1.00 72.86  ? 290 GLN C O     1 
ATOM   10391 C CB    . GLN C 1 290 ? -36.282 2.326   -93.145  1.00 64.69  ? 290 GLN C CB    1 
ATOM   10392 C CG    . GLN C 1 290 ? -37.183 1.430   -92.308  1.00 69.65  ? 290 GLN C CG    1 
ATOM   10393 C CD    . GLN C 1 290 ? -37.566 2.109   -91.016  1.00 78.45  ? 290 GLN C CD    1 
ATOM   10394 O OE1   . GLN C 1 290 ? -36.708 2.608   -90.291  1.00 89.77  ? 290 GLN C OE1   1 
ATOM   10395 N NE2   . GLN C 1 290 ? -38.855 2.149   -90.711  1.00 79.24  ? 290 GLN C NE2   1 
ATOM   10396 N N     . TYR C 1 291 ? -33.290 2.298   -94.927  1.00 69.03  ? 291 TYR C N     1 
ATOM   10397 C CA    . TYR C 1 291 ? -32.279 3.162   -95.537  1.00 64.34  ? 291 TYR C CA    1 
ATOM   10398 C C     . TYR C 1 291 ? -31.236 2.402   -96.373  1.00 69.85  ? 291 TYR C C     1 
ATOM   10399 O O     . TYR C 1 291 ? -30.619 3.030   -97.239  1.00 68.04  ? 291 TYR C O     1 
ATOM   10400 C CB    . TYR C 1 291 ? -31.517 3.955   -94.469  1.00 67.32  ? 291 TYR C CB    1 
ATOM   10401 C CG    . TYR C 1 291 ? -32.307 5.031   -93.762  1.00 69.41  ? 291 TYR C CG    1 
ATOM   10402 C CD1   . TYR C 1 291 ? -32.645 6.213   -94.404  1.00 66.67  ? 291 TYR C CD1   1 
ATOM   10403 C CD2   . TYR C 1 291 ? -32.717 4.873   -92.448  1.00 65.91  ? 291 TYR C CD2   1 
ATOM   10404 C CE1   . TYR C 1 291 ? -33.374 7.202   -93.766  1.00 68.29  ? 291 TYR C CE1   1 
ATOM   10405 C CE2   . TYR C 1 291 ? -33.449 5.852   -91.795  1.00 61.95  ? 291 TYR C CE2   1 
ATOM   10406 C CZ    . TYR C 1 291 ? -33.770 7.024   -92.451  1.00 70.93  ? 291 TYR C CZ    1 
ATOM   10407 O OH    . TYR C 1 291 ? -34.505 8.004   -91.821  1.00 77.25  ? 291 TYR C OH    1 
ATOM   10408 N N     . TYR C 1 292 ? -31.011 1.088   -96.126  1.00 68.00  ? 292 TYR C N     1 
ATOM   10409 C CA    . TYR C 1 292 ? -29.956 0.341   -96.814  1.00 74.76  ? 292 TYR C CA    1 
ATOM   10410 C C     . TYR C 1 292 ? -30.306 -1.150  -96.986  1.00 79.95  ? 292 TYR C C     1 
ATOM   10411 O O     . TYR C 1 292 ? -30.694 -1.826  -96.032  1.00 70.12  ? 292 TYR C O     1 
ATOM   10412 C CB    . TYR C 1 292 ? -28.630 0.549   -96.065  1.00 76.01  ? 292 TYR C CB    1 
ATOM   10413 C CG    . TYR C 1 292 ? -27.445 -0.210  -96.612  1.00 72.41  ? 292 TYR C CG    1 
ATOM   10414 C CD1   . TYR C 1 292 ? -26.871 0.131   -97.830  1.00 68.78  ? 292 TYR C CD1   1 
ATOM   10415 C CD2   . TYR C 1 292 ? -26.910 -1.291  -95.921  1.00 82.66  ? 292 TYR C CD2   1 
ATOM   10416 C CE1   . TYR C 1 292 ? -25.799 -0.578  -98.350  1.00 62.57  ? 292 TYR C CE1   1 
ATOM   10417 C CE2   . TYR C 1 292 ? -25.837 -2.011  -96.428  1.00 82.95  ? 292 TYR C CE2   1 
ATOM   10418 C CZ    . TYR C 1 292 ? -25.279 -1.649  -97.645  1.00 74.01  ? 292 TYR C CZ    1 
ATOM   10419 O OH    . TYR C 1 292 ? -24.220 -2.363  -98.149  1.00 80.01  ? 292 TYR C OH    1 
ATOM   10420 N N     . ASP C 1 293 ? -30.098 -1.679  -98.210  1.00 84.19  ? 293 ASP C N     1 
ATOM   10421 C CA    . ASP C 1 293 ? -30.471 -3.049  -98.555  1.00 92.62  ? 293 ASP C CA    1 
ATOM   10422 C C     . ASP C 1 293 ? -29.501 -4.058  -97.952  1.00 82.79  ? 293 ASP C C     1 
ATOM   10423 O O     . ASP C 1 293 ? -29.938 -4.979  -97.272  1.00 76.61  ? 293 ASP C O     1 
ATOM   10424 C CB    . ASP C 1 293 ? -30.512 -3.295  -100.073 1.00 105.30 ? 293 ASP C CB    1 
ATOM   10425 C CG    . ASP C 1 293 ? -31.904 -3.377  -100.695 1.00 119.78 ? 293 ASP C CG    1 
ATOM   10426 O OD1   . ASP C 1 293 ? -32.903 -3.361  -99.945  1.00 127.22 ? 293 ASP C OD1   1 
ATOM   10427 O OD2   . ASP C 1 293 ? -31.985 -3.469  -101.938 1.00 116.15 ? 293 ASP C OD2   1 
ATOM   10428 N N     . GLY C 1 294 ? -28.201 -3.862  -98.230  1.00 87.74  ? 294 GLY C N     1 
ATOM   10429 C CA    . GLY C 1 294 ? -27.161 -4.876  -98.102  1.00 85.04  ? 294 GLY C CA    1 
ATOM   10430 C C     . GLY C 1 294 ? -26.978 -5.406  -96.682  1.00 92.77  ? 294 GLY C C     1 
ATOM   10431 O O     . GLY C 1 294 ? -27.466 -4.809  -95.725  1.00 97.69  ? 294 GLY C O     1 
ATOM   10432 N N     . ASP C 1 295 ? -26.243 -6.527  -96.571  1.00 108.14 ? 295 ASP C N     1 
ATOM   10433 C CA    . ASP C 1 295 ? -26.087 -7.260  -95.318  1.00 117.65 ? 295 ASP C CA    1 
ATOM   10434 C C     . ASP C 1 295 ? -24.987 -6.617  -94.456  1.00 110.13 ? 295 ASP C C     1 
ATOM   10435 O O     . ASP C 1 295 ? -24.950 -6.821  -93.230  1.00 82.07  ? 295 ASP C O     1 
ATOM   10436 C CB    . ASP C 1 295 ? -25.788 -8.754  -95.551  1.00 119.74 ? 295 ASP C CB    1 
ATOM   10437 C CG    . ASP C 1 295 ? -26.629 -9.493  -96.590  1.00 115.68 ? 295 ASP C CG    1 
ATOM   10438 O OD1   . ASP C 1 295 ? -27.877 -9.371  -96.573  1.00 113.23 ? 295 ASP C OD1   1 
ATOM   10439 O OD2   . ASP C 1 295 ? -26.029 -10.232 -97.388  1.00 94.81  ? 295 ASP C OD2   1 
ATOM   10440 N N     . GLY C 1 296 ? -24.095 -5.838  -95.101  1.00 92.43  ? 296 GLY C N     1 
ATOM   10441 C CA    . GLY C 1 296 ? -22.960 -5.223  -94.430  1.00 87.88  ? 296 GLY C CA    1 
ATOM   10442 C C     . GLY C 1 296 ? -23.355 -4.033  -93.554  1.00 88.06  ? 296 GLY C C     1 
ATOM   10443 O O     . GLY C 1 296 ? -24.532 -3.722  -93.400  1.00 101.27 ? 296 GLY C O     1 
ATOM   10444 N N     . PRO C 1 297 ? -22.382 -3.367  -92.890  1.00 87.94  ? 297 PRO C N     1 
ATOM   10445 C CA    . PRO C 1 297 ? -22.619 -2.066  -92.257  1.00 82.62  ? 297 PRO C CA    1 
ATOM   10446 C C     . PRO C 1 297 ? -22.843 -0.931  -93.263  1.00 77.69  ? 297 PRO C C     1 
ATOM   10447 O O     . PRO C 1 297 ? -22.355 -0.976  -94.389  1.00 71.46  ? 297 PRO C O     1 
ATOM   10448 C CB    . PRO C 1 297 ? -21.335 -1.793  -91.443  1.00 91.48  ? 297 PRO C CB    1 
ATOM   10449 C CG    . PRO C 1 297 ? -20.576 -3.113  -91.409  1.00 91.89  ? 297 PRO C CG    1 
ATOM   10450 C CD    . PRO C 1 297 ? -21.026 -3.879  -92.637  1.00 92.41  ? 297 PRO C CD    1 
ATOM   10451 N N     . ILE C 1 298 ? -23.525 0.127   -92.815  1.00 75.15  ? 298 ILE C N     1 
ATOM   10452 C CA    . ILE C 1 298 ? -23.987 1.182   -93.702  1.00 74.42  ? 298 ILE C CA    1 
ATOM   10453 C C     . ILE C 1 298 ? -22.788 1.901   -94.315  1.00 72.90  ? 298 ILE C C     1 
ATOM   10454 O O     . ILE C 1 298 ? -21.768 2.113   -93.661  1.00 71.23  ? 298 ILE C O     1 
ATOM   10455 C CB    . ILE C 1 298 ? -24.939 2.161   -92.978  1.00 84.23  ? 298 ILE C CB    1 
ATOM   10456 C CG1   . ILE C 1 298 ? -24.220 3.050   -91.963  1.00 84.95  ? 298 ILE C CG1   1 
ATOM   10457 C CG2   . ILE C 1 298 ? -26.110 1.435   -92.323  1.00 87.66  ? 298 ILE C CG2   1 
ATOM   10458 C CD1   . ILE C 1 298 ? -25.033 4.239   -91.539  1.00 85.11  ? 298 ILE C CD1   1 
ATOM   10459 N N     . PRO C 1 299 ? -22.860 2.259   -95.615  1.00 80.65  ? 299 PRO C N     1 
ATOM   10460 C CA    . PRO C 1 299 ? -21.884 3.166   -96.233  1.00 80.81  ? 299 PRO C CA    1 
ATOM   10461 C C     . PRO C 1 299 ? -22.166 4.658   -96.030  1.00 78.27  ? 299 PRO C C     1 
ATOM   10462 O O     . PRO C 1 299 ? -23.246 5.044   -95.590  1.00 74.79  ? 299 PRO C O     1 
ATOM   10463 C CB    . PRO C 1 299 ? -21.983 2.791   -97.718  1.00 81.14  ? 299 PRO C CB    1 
ATOM   10464 C CG    . PRO C 1 299 ? -23.420 2.319   -97.905  1.00 80.24  ? 299 PRO C CG    1 
ATOM   10465 C CD    . PRO C 1 299 ? -23.832 1.719   -96.577  1.00 79.36  ? 299 PRO C CD    1 
ATOM   10466 N N     . PRO C 1 300 ? -21.209 5.552   -96.372  1.00 83.43  ? 300 PRO C N     1 
ATOM   10467 C CA    . PRO C 1 300 ? -21.246 6.941   -95.912  1.00 89.36  ? 300 PRO C CA    1 
ATOM   10468 C C     . PRO C 1 300 ? -22.309 7.814   -96.575  1.00 94.61  ? 300 PRO C C     1 
ATOM   10469 O O     . PRO C 1 300 ? -22.696 8.847   -96.020  1.00 90.64  ? 300 PRO C O     1 
ATOM   10470 C CB    . PRO C 1 300 ? -19.860 7.522   -96.253  1.00 84.96  ? 300 PRO C CB    1 
ATOM   10471 C CG    . PRO C 1 300 ? -19.085 6.410   -96.950  1.00 87.87  ? 300 PRO C CG    1 
ATOM   10472 C CD    . PRO C 1 300 ? -20.055 5.283   -97.241  1.00 86.59  ? 300 PRO C CD    1 
ATOM   10473 N N     . SER C 1 301 ? -22.731 7.405   -97.780  1.00 98.78  ? 301 SER C N     1 
ATOM   10474 C CA    . SER C 1 301 ? -23.722 8.122   -98.569  1.00 88.64  ? 301 SER C CA    1 
ATOM   10475 C C     . SER C 1 301 ? -25.108 7.956   -97.944  1.00 77.12  ? 301 SER C C     1 
ATOM   10476 O O     . SER C 1 301 ? -25.924 8.878   -98.000  1.00 76.48  ? 301 SER C O     1 
ATOM   10477 C CB    . SER C 1 301 ? -23.701 7.636   -100.000 1.00 85.24  ? 301 SER C CB    1 
ATOM   10478 O OG    . SER C 1 301 ? -24.219 6.314   -100.088 1.00 81.22  ? 301 SER C OG    1 
ATOM   10479 N N     . VAL C 1 302 ? -25.347 6.767   -97.372  1.00 63.89  ? 302 VAL C N     1 
ATOM   10480 C CA    . VAL C 1 302 ? -26.575 6.451   -96.667  1.00 77.01  ? 302 VAL C CA    1 
ATOM   10481 C C     . VAL C 1 302 ? -26.607 7.158   -95.312  1.00 92.18  ? 302 VAL C C     1 
ATOM   10482 O O     . VAL C 1 302 ? -27.681 7.371   -94.742  1.00 91.49  ? 302 VAL C O     1 
ATOM   10483 C CB    . VAL C 1 302 ? -26.728 4.931   -96.489  1.00 79.25  ? 302 VAL C CB    1 
ATOM   10484 C CG1   . VAL C 1 302 ? -27.805 4.594   -95.469  1.00 83.62  ? 302 VAL C CG1   1 
ATOM   10485 C CG2   . VAL C 1 302 ? -27.007 4.232   -97.812  1.00 85.29  ? 302 VAL C CG2   1 
ATOM   10486 N N     . ALA C 1 303 ? -25.423 7.479   -94.777  1.00 94.74  ? 303 ALA C N     1 
ATOM   10487 C CA    . ALA C 1 303 ? -25.338 8.265   -93.560  1.00 90.49  ? 303 ALA C CA    1 
ATOM   10488 C C     . ALA C 1 303 ? -25.890 9.672   -93.810  1.00 86.87  ? 303 ALA C C     1 
ATOM   10489 O O     . ALA C 1 303 ? -26.713 10.147  -93.037  1.00 90.43  ? 303 ALA C O     1 
ATOM   10490 C CB    . ALA C 1 303 ? -23.916 8.277   -93.051  1.00 81.83  ? 303 ALA C CB    1 
ATOM   10491 N N     . LYS C 1 304 ? -25.449 10.334  -94.889  1.00 83.00  ? 304 LYS C N     1 
ATOM   10492 C CA    . LYS C 1 304 ? -25.851 11.705  -95.174  1.00 86.12  ? 304 LYS C CA    1 
ATOM   10493 C C     . LYS C 1 304 ? -27.365 11.779  -95.367  1.00 80.60  ? 304 LYS C C     1 
ATOM   10494 O O     . LYS C 1 304 ? -27.996 12.767  -94.990  1.00 76.52  ? 304 LYS C O     1 
ATOM   10495 C CB    . LYS C 1 304 ? -25.084 12.223  -96.394  1.00 96.74  ? 304 LYS C CB    1 
ATOM   10496 C CG    . LYS C 1 304 ? -23.705 12.804  -96.091  1.00 113.24 ? 304 LYS C CG    1 
ATOM   10497 C CD    . LYS C 1 304 ? -22.552 12.201  -96.902  1.00 134.04 ? 304 LYS C CD    1 
ATOM   10498 C CE    . LYS C 1 304 ? -22.803 12.043  -98.395  1.00 138.70 ? 304 LYS C CE    1 
ATOM   10499 N NZ    . LYS C 1 304 ? -21.724 12.633  -99.231  1.00 125.00 ? 304 LYS C NZ    1 
ATOM   10500 N N     . THR C 1 305 ? -27.938 10.707  -95.923  1.00 74.72  ? 305 THR C N     1 
ATOM   10501 C CA    . THR C 1 305 ? -29.378 10.597  -96.103  1.00 80.99  ? 305 THR C CA    1 
ATOM   10502 C C     . THR C 1 305 ? -30.107 10.569  -94.756  1.00 77.59  ? 305 THR C C     1 
ATOM   10503 O O     . THR C 1 305 ? -31.001 11.388  -94.531  1.00 80.48  ? 305 THR C O     1 
ATOM   10504 C CB    . THR C 1 305 ? -29.703 9.361   -96.955  1.00 84.19  ? 305 THR C CB    1 
ATOM   10505 O OG1   . THR C 1 305 ? -29.112 9.602   -98.229  1.00 75.98  ? 305 THR C OG1   1 
ATOM   10506 C CG2   . THR C 1 305 ? -31.184 9.075   -97.114  1.00 83.78  ? 305 THR C CG2   1 
ATOM   10507 N N     . MET C 1 306 ? -29.723 9.621   -93.880  1.00 70.88  ? 306 MET C N     1 
ATOM   10508 C CA    . MET C 1 306 ? -30.313 9.423   -92.553  1.00 70.56  ? 306 MET C CA    1 
ATOM   10509 C C     . MET C 1 306 ? -30.356 10.711  -91.731  1.00 69.77  ? 306 MET C C     1 
ATOM   10510 O O     . MET C 1 306 ? -31.250 10.846  -90.902  1.00 67.10  ? 306 MET C O     1 
ATOM   10511 C CB    . MET C 1 306 ? -29.514 8.395   -91.748  1.00 78.24  ? 306 MET C CB    1 
ATOM   10512 C CG    . MET C 1 306 ? -29.772 6.955   -92.161  1.00 86.66  ? 306 MET C CG    1 
ATOM   10513 S SD    . MET C 1 306 ? -28.640 5.761   -91.393  1.00 81.60  ? 306 MET C SD    1 
ATOM   10514 C CE    . MET C 1 306 ? -29.409 5.659   -89.777  1.00 82.41  ? 306 MET C CE    1 
ATOM   10515 N N     . MET C 1 307 ? -29.397 11.623  -91.984  1.00 67.78  ? 307 MET C N     1 
ATOM   10516 C CA    . MET C 1 307 ? -29.187 12.856  -91.237  1.00 74.82  ? 307 MET C CA    1 
ATOM   10517 C C     . MET C 1 307 ? -30.183 13.941  -91.643  1.00 82.76  ? 307 MET C C     1 
ATOM   10518 O O     . MET C 1 307 ? -30.795 14.573  -90.780  1.00 85.75  ? 307 MET C O     1 
ATOM   10519 C CB    . MET C 1 307 ? -27.771 13.392  -91.492  1.00 77.35  ? 307 MET C CB    1 
ATOM   10520 C CG    . MET C 1 307 ? -26.728 12.831  -90.546  1.00 74.40  ? 307 MET C CG    1 
ATOM   10521 S SD    . MET C 1 307 ? -25.043 13.233  -91.040  1.00 75.94  ? 307 MET C SD    1 
ATOM   10522 C CE    . MET C 1 307 ? -25.082 15.025  -90.939  1.00 70.60  ? 307 MET C CE    1 
ATOM   10523 N N     . ALA C 1 308 ? -30.277 14.204  -92.956  1.00 89.65  ? 308 ALA C N     1 
ATOM   10524 C CA    . ALA C 1 308 ? -31.263 15.133  -93.488  1.00 83.58  ? 308 ALA C CA    1 
ATOM   10525 C C     . ALA C 1 308 ? -32.675 14.615  -93.207  1.00 73.06  ? 308 ALA C C     1 
ATOM   10526 O O     . ALA C 1 308 ? -33.574 15.399  -92.915  1.00 70.53  ? 308 ALA C O     1 
ATOM   10527 C CB    . ALA C 1 308 ? -31.028 15.350  -94.962  1.00 84.65  ? 308 ALA C CB    1 
ATOM   10528 N N     . ASP C 1 309 ? -32.860 13.288  -93.232  1.00 70.75  ? 309 ASP C N     1 
ATOM   10529 C CA    . ASP C 1 309 ? -34.168 12.699  -92.966  1.00 77.67  ? 309 ASP C CA    1 
ATOM   10530 C C     . ASP C 1 309 ? -34.599 12.921  -91.512  1.00 76.65  ? 309 ASP C C     1 
ATOM   10531 O O     . ASP C 1 309 ? -35.722 13.361  -91.266  1.00 95.83  ? 309 ASP C O     1 
ATOM   10532 C CB    . ASP C 1 309 ? -34.192 11.208  -93.317  1.00 78.42  ? 309 ASP C CB    1 
ATOM   10533 C CG    . ASP C 1 309 ? -35.583 10.596  -93.359  1.00 82.54  ? 309 ASP C CG    1 
ATOM   10534 O OD1   . ASP C 1 309 ? -36.564 11.363  -93.450  1.00 84.99  ? 309 ASP C OD1   1 
ATOM   10535 O OD2   . ASP C 1 309 ? -35.676 9.354   -93.290  1.00 88.71  ? 309 ASP C OD2   1 
ATOM   10536 N N     . LEU C 1 310 ? -33.714 12.613  -90.551  1.00 74.37  ? 310 LEU C N     1 
ATOM   10537 C CA    . LEU C 1 310 ? -34.092 12.519  -89.145  1.00 71.95  ? 310 LEU C CA    1 
ATOM   10538 C C     . LEU C 1 310 ? -33.768 13.790  -88.362  1.00 69.61  ? 310 LEU C C     1 
ATOM   10539 O O     . LEU C 1 310 ? -34.167 13.883  -87.205  1.00 61.35  ? 310 LEU C O     1 
ATOM   10540 C CB    . LEU C 1 310 ? -33.341 11.351  -88.503  1.00 63.96  ? 310 LEU C CB    1 
ATOM   10541 C CG    . LEU C 1 310 ? -33.739 9.952   -88.940  1.00 62.06  ? 310 LEU C CG    1 
ATOM   10542 C CD1   . LEU C 1 310 ? -32.664 8.951   -88.538  1.00 67.78  ? 310 LEU C CD1   1 
ATOM   10543 C CD2   . LEU C 1 310 ? -35.069 9.556   -88.320  1.00 68.98  ? 310 LEU C CD2   1 
ATOM   10544 N N     . ASP C 1 311 ? -33.011 14.718  -88.971  1.00 80.47  ? 311 ASP C N     1 
ATOM   10545 C CA    . ASP C 1 311 ? -32.578 15.961  -88.335  1.00 92.56  ? 311 ASP C CA    1 
ATOM   10546 C C     . ASP C 1 311 ? -31.529 15.668  -87.261  1.00 87.44  ? 311 ASP C C     1 
ATOM   10547 O O     . ASP C 1 311 ? -31.521 16.279  -86.197  1.00 87.37  ? 311 ASP C O     1 
ATOM   10548 C CB    . ASP C 1 311 ? -33.757 16.797  -87.806  1.00 89.16  ? 311 ASP C CB    1 
ATOM   10549 C CG    . ASP C 1 311 ? -34.347 17.729  -88.849  1.00 88.87  ? 311 ASP C CG    1 
ATOM   10550 O OD1   . ASP C 1 311 ? -33.739 17.840  -89.927  1.00 92.61  ? 311 ASP C OD1   1 
ATOM   10551 O OD2   . ASP C 1 311 ? -35.403 18.337  -88.575  1.00 92.80  ? 311 ASP C OD2   1 
ATOM   10552 N N     . LEU C 1 312 ? -30.609 14.764  -87.594  1.00 81.21  ? 312 LEU C N     1 
ATOM   10553 C CA    . LEU C 1 312 ? -29.478 14.452  -86.746  1.00 72.54  ? 312 LEU C CA    1 
ATOM   10554 C C     . LEU C 1 312 ? -28.187 14.872  -87.453  1.00 76.35  ? 312 LEU C C     1 
ATOM   10555 O O     . LEU C 1 312 ? -28.184 15.167  -88.657  1.00 71.01  ? 312 LEU C O     1 
ATOM   10556 C CB    . LEU C 1 312 ? -29.532 12.956  -86.428  1.00 66.28  ? 312 LEU C CB    1 
ATOM   10557 C CG    . LEU C 1 312 ? -30.840 12.493  -85.770  1.00 67.99  ? 312 LEU C CG    1 
ATOM   10558 C CD1   . LEU C 1 312 ? -30.835 10.999  -85.489  1.00 65.24  ? 312 LEU C CD1   1 
ATOM   10559 C CD2   . LEU C 1 312 ? -31.119 13.242  -84.475  1.00 67.69  ? 312 LEU C CD2   1 
ATOM   10560 N N     . GLY C 1 313 ? -27.127 15.002  -86.642  1.00 69.55  ? 313 GLY C N     1 
ATOM   10561 C CA    . GLY C 1 313 ? -25.749 15.080  -87.098  1.00 61.23  ? 313 GLY C CA    1 
ATOM   10562 C C     . GLY C 1 313 ? -25.063 13.714  -87.010  1.00 62.72  ? 313 GLY C C     1 
ATOM   10563 O O     . GLY C 1 313 ? -25.700 12.690  -86.758  1.00 61.49  ? 313 GLY C O     1 
ATOM   10564 N N     . MET C 1 314 ? -23.755 13.694  -87.271  1.00 64.13  ? 314 MET C N     1 
ATOM   10565 C CA    . MET C 1 314 ? -22.955 12.506  -87.039  1.00 57.90  ? 314 MET C CA    1 
ATOM   10566 C C     . MET C 1 314 ? -22.791 12.341  -85.524  1.00 60.69  ? 314 MET C C     1 
ATOM   10567 O O     . MET C 1 314 ? -22.714 11.223  -85.007  1.00 50.03  ? 314 MET C O     1 
ATOM   10568 C CB    . MET C 1 314 ? -21.609 12.639  -87.760  1.00 61.53  ? 314 MET C CB    1 
ATOM   10569 C CG    . MET C 1 314 ? -21.735 12.531  -89.294  1.00 68.91  ? 314 MET C CG    1 
ATOM   10570 S SD    . MET C 1 314 ? -22.058 10.840  -90.006  1.00 75.59  ? 314 MET C SD    1 
ATOM   10571 C CE    . MET C 1 314 ? -20.820 9.814   -89.211  1.00 85.83  ? 314 MET C CE    1 
ATOM   10572 N N     . TRP C 1 315 ? -22.807 13.483  -84.816  1.00 63.71  ? 315 TRP C N     1 
ATOM   10573 C CA    . TRP C 1 315 ? -22.730 13.533  -83.361  1.00 64.94  ? 315 TRP C CA    1 
ATOM   10574 C C     . TRP C 1 315 ? -23.884 14.367  -82.813  1.00 61.28  ? 315 TRP C C     1 
ATOM   10575 O O     . TRP C 1 315 ? -24.152 15.449  -83.315  1.00 50.16  ? 315 TRP C O     1 
ATOM   10576 C CB    . TRP C 1 315 ? -21.370 14.077  -82.904  1.00 59.78  ? 315 TRP C CB    1 
ATOM   10577 C CG    . TRP C 1 315 ? -20.251 13.156  -83.269  1.00 58.52  ? 315 TRP C CG    1 
ATOM   10578 C CD1   . TRP C 1 315 ? -19.303 13.342  -84.233  1.00 61.78  ? 315 TRP C CD1   1 
ATOM   10579 C CD2   . TRP C 1 315 ? -19.993 11.864  -82.704  1.00 52.21  ? 315 TRP C CD2   1 
ATOM   10580 N NE1   . TRP C 1 315 ? -18.467 12.260  -84.298  1.00 56.15  ? 315 TRP C NE1   1 
ATOM   10581 C CE2   . TRP C 1 315 ? -18.864 11.339  -83.369  1.00 58.28  ? 315 TRP C CE2   1 
ATOM   10582 C CE3   . TRP C 1 315 ? -20.602 11.107  -81.705  1.00 50.38  ? 315 TRP C CE3   1 
ATOM   10583 C CZ2   . TRP C 1 315 ? -18.318 10.098  -83.049  1.00 57.77  ? 315 TRP C CZ2   1 
ATOM   10584 C CZ3   . TRP C 1 315 ? -20.066 9.878   -81.393  1.00 56.73  ? 315 TRP C CZ3   1 
ATOM   10585 C CH2   . TRP C 1 315 ? -18.947 9.378   -82.062  1.00 56.43  ? 315 TRP C CH2   1 
ATOM   10586 N N     . ASN C 1 316 ? -24.553 13.835  -81.775  1.00 69.35  ? 316 ASN C N     1 
ATOM   10587 C CA    . ASN C 1 316 ? -25.748 14.443  -81.212  1.00 69.28  ? 316 ASN C CA    1 
ATOM   10588 C C     . ASN C 1 316 ? -25.610 14.506  -79.693  1.00 66.97  ? 316 ASN C C     1 
ATOM   10589 O O     . ASN C 1 316 ? -25.585 13.461  -79.039  1.00 64.90  ? 316 ASN C O     1 
ATOM   10590 C CB    . ASN C 1 316 ? -26.982 13.652  -81.637  1.00 69.46  ? 316 ASN C CB    1 
ATOM   10591 C CG    . ASN C 1 316 ? -26.915 13.289  -83.103  1.00 72.29  ? 316 ASN C CG    1 
ATOM   10592 O OD1   . ASN C 1 316 ? -27.259 14.106  -83.955  1.00 64.33  ? 316 ASN C OD1   1 
ATOM   10593 N ND2   . ASN C 1 316 ? -26.434 12.088  -83.401  1.00 74.21  ? 316 ASN C ND2   1 
ATOM   10594 N N     . PHE C 1 317 ? -25.536 15.746  -79.174  1.00 62.66  ? 317 PHE C N     1 
ATOM   10595 C CA    . PHE C 1 317 ? -25.321 16.041  -77.767  1.00 52.57  ? 317 PHE C CA    1 
ATOM   10596 C C     . PHE C 1 317 ? -26.649 16.396  -77.120  1.00 50.87  ? 317 PHE C C     1 
ATOM   10597 O O     . PHE C 1 317 ? -27.134 17.487  -77.338  1.00 51.29  ? 317 PHE C O     1 
ATOM   10598 C CB    . PHE C 1 317 ? -24.322 17.189  -77.660  1.00 55.27  ? 317 PHE C CB    1 
ATOM   10599 C CG    . PHE C 1 317 ? -24.246 17.918  -76.341  1.00 58.43  ? 317 PHE C CG    1 
ATOM   10600 C CD1   . PHE C 1 317 ? -24.390 17.257  -75.134  1.00 58.42  ? 317 PHE C CD1   1 
ATOM   10601 C CD2   . PHE C 1 317 ? -23.961 19.275  -76.309  1.00 58.77  ? 317 PHE C CD2   1 
ATOM   10602 C CE1   . PHE C 1 317 ? -24.287 17.936  -73.930  1.00 52.09  ? 317 PHE C CE1   1 
ATOM   10603 C CE2   . PHE C 1 317 ? -23.863 19.953  -75.104  1.00 53.29  ? 317 PHE C CE2   1 
ATOM   10604 C CZ    . PHE C 1 317 ? -24.025 19.278  -73.918  1.00 53.20  ? 317 PHE C CZ    1 
ATOM   10605 N N     . CYS C 1 318 ? -27.238 15.452  -76.371  1.00 61.07  ? 318 CYS C N     1 
ATOM   10606 C CA    . CYS C 1 318 ? -28.440 15.695  -75.578  1.00 66.11  ? 318 CYS C CA    1 
ATOM   10607 C C     . CYS C 1 318 ? -28.041 15.988  -74.121  1.00 65.25  ? 318 CYS C C     1 
ATOM   10608 O O     . CYS C 1 318 ? -27.216 15.297  -73.511  1.00 49.90  ? 318 CYS C O     1 
ATOM   10609 C CB    . CYS C 1 318 ? -29.475 14.568  -75.706  1.00 63.99  ? 318 CYS C CB    1 
ATOM   10610 S SG    . CYS C 1 318 ? -28.844 12.882  -75.463  1.00 74.15  ? 318 CYS C SG    1 
ATOM   10611 N N     . GLY C 1 319 ? -28.591 17.094  -73.601  1.00 66.19  ? 319 GLY C N     1 
ATOM   10612 C CA    . GLY C 1 319 ? -28.333 17.560  -72.247  1.00 65.32  ? 319 GLY C CA    1 
ATOM   10613 C C     . GLY C 1 319 ? -29.552 18.280  -71.680  1.00 64.62  ? 319 GLY C C     1 
ATOM   10614 O O     . GLY C 1 319 ? -30.609 18.348  -72.327  1.00 68.03  ? 319 GLY C O     1 
ATOM   10615 N N     . ALA C 1 320 ? -29.388 18.831  -70.476  1.00 54.47  ? 320 ALA C N     1 
ATOM   10616 C CA    . ALA C 1 320 ? -30.491 19.490  -69.805  1.00 53.05  ? 320 ALA C CA    1 
ATOM   10617 C C     . ALA C 1 320 ? -29.995 20.552  -68.833  1.00 57.88  ? 320 ALA C C     1 
ATOM   10618 O O     . ALA C 1 320 ? -28.981 20.374  -68.158  1.00 51.53  ? 320 ALA C O     1 
ATOM   10619 C CB    . ALA C 1 320 ? -31.300 18.470  -69.073  1.00 59.97  ? 320 ALA C CB    1 
ATOM   10620 N N     . LEU C 1 321 ? -30.778 21.637  -68.764  1.00 56.63  ? 321 LEU C N     1 
ATOM   10621 C CA    . LEU C 1 321 ? -30.617 22.681  -67.778  1.00 54.07  ? 321 LEU C CA    1 
ATOM   10622 C C     . LEU C 1 321 ? -31.607 22.418  -66.654  1.00 54.11  ? 321 LEU C C     1 
ATOM   10623 O O     . LEU C 1 321 ? -32.721 21.982  -66.914  1.00 61.13  ? 321 LEU C O     1 
ATOM   10624 C CB    . LEU C 1 321 ? -30.905 24.027  -68.442  1.00 60.06  ? 321 LEU C CB    1 
ATOM   10625 C CG    . LEU C 1 321 ? -30.251 24.229  -69.805  1.00 60.14  ? 321 LEU C CG    1 
ATOM   10626 C CD1   . LEU C 1 321 ? -30.683 25.554  -70.411  1.00 62.82  ? 321 LEU C CD1   1 
ATOM   10627 C CD2   . LEU C 1 321 ? -28.733 24.162  -69.680  1.00 63.28  ? 321 LEU C CD2   1 
ATOM   10628 N N     . TYR C 1 322 ? -31.182 22.674  -65.411  1.00 56.63  ? 322 TYR C N     1 
ATOM   10629 C CA    . TYR C 1 322 ? -32.045 22.517  -64.255  1.00 56.76  ? 322 TYR C CA    1 
ATOM   10630 C C     . TYR C 1 322 ? -31.945 23.781  -63.412  1.00 60.06  ? 322 TYR C C     1 
ATOM   10631 O O     . TYR C 1 322 ? -30.851 24.311  -63.267  1.00 57.49  ? 322 TYR C O     1 
ATOM   10632 C CB    . TYR C 1 322 ? -31.652 21.290  -63.440  1.00 52.55  ? 322 TYR C CB    1 
ATOM   10633 C CG    . TYR C 1 322 ? -31.495 20.006  -64.218  1.00 48.53  ? 322 TYR C CG    1 
ATOM   10634 C CD1   . TYR C 1 322 ? -30.356 19.768  -64.969  1.00 43.80  ? 322 TYR C CD1   1 
ATOM   10635 C CD2   . TYR C 1 322 ? -32.438 18.994  -64.136  1.00 47.18  ? 322 TYR C CD2   1 
ATOM   10636 C CE1   . TYR C 1 322 ? -30.169 18.576  -65.651  1.00 50.23  ? 322 TYR C CE1   1 
ATOM   10637 C CE2   . TYR C 1 322 ? -32.275 17.799  -64.829  1.00 52.40  ? 322 TYR C CE2   1 
ATOM   10638 C CZ    . TYR C 1 322 ? -31.137 17.587  -65.596  1.00 50.94  ? 322 TYR C CZ    1 
ATOM   10639 O OH    . TYR C 1 322 ? -30.934 16.401  -66.275  1.00 52.30  ? 322 TYR C OH    1 
ATOM   10640 N N     . GLY C 1 323 ? -33.097 24.285  -62.937  1.00 57.26  ? 323 GLY C N     1 
ATOM   10641 C CA    . GLY C 1 323 ? -33.133 25.376  -61.980  1.00 51.87  ? 323 GLY C CA    1 
ATOM   10642 C C     . GLY C 1 323 ? -34.153 26.461  -62.331  1.00 59.81  ? 323 GLY C C     1 
ATOM   10643 O O     . GLY C 1 323 ? -34.991 26.308  -63.228  1.00 58.50  ? 323 GLY C O     1 
ATOM   10644 N N     . PRO C 1 324 ? -34.109 27.604  -61.602  1.00 62.30  ? 324 PRO C N     1 
ATOM   10645 C CA    . PRO C 1 324 ? -35.016 28.714  -61.851  1.00 63.34  ? 324 PRO C CA    1 
ATOM   10646 C C     . PRO C 1 324 ? -34.729 29.292  -63.229  1.00 62.89  ? 324 PRO C C     1 
ATOM   10647 O O     . PRO C 1 324 ? -33.577 29.311  -63.644  1.00 60.37  ? 324 PRO C O     1 
ATOM   10648 C CB    . PRO C 1 324 ? -34.716 29.762  -60.766  1.00 60.91  ? 324 PRO C CB    1 
ATOM   10649 C CG    . PRO C 1 324 ? -33.570 29.227  -59.932  1.00 61.32  ? 324 PRO C CG    1 
ATOM   10650 C CD    . PRO C 1 324 ? -33.164 27.883  -60.503  1.00 63.47  ? 324 PRO C CD    1 
ATOM   10651 N N     . PRO C 1 325 ? -35.748 29.789  -63.963  1.00 76.24  ? 325 PRO C N     1 
ATOM   10652 C CA    . PRO C 1 325 ? -35.530 30.412  -65.282  1.00 93.58  ? 325 PRO C CA    1 
ATOM   10653 C C     . PRO C 1 325 ? -34.375 31.424  -65.438  1.00 88.30  ? 325 PRO C C     1 
ATOM   10654 O O     . PRO C 1 325 ? -33.650 31.364  -66.431  1.00 73.41  ? 325 PRO C O     1 
ATOM   10655 C CB    . PRO C 1 325 ? -36.909 31.036  -65.573  1.00 87.52  ? 325 PRO C CB    1 
ATOM   10656 C CG    . PRO C 1 325 ? -37.876 30.082  -64.896  1.00 84.89  ? 325 PRO C CG    1 
ATOM   10657 C CD    . PRO C 1 325 ? -37.174 29.707  -63.602  1.00 75.21  ? 325 PRO C CD    1 
ATOM   10658 N N     . PRO C 1 326 ? -34.114 32.377  -64.507  1.00 86.48  ? 326 PRO C N     1 
ATOM   10659 C CA    . PRO C 1 326 ? -32.884 33.178  -64.580  1.00 85.47  ? 326 PRO C CA    1 
ATOM   10660 C C     . PRO C 1 326 ? -31.575 32.394  -64.734  1.00 83.42  ? 326 PRO C C     1 
ATOM   10661 O O     . PRO C 1 326 ? -30.689 32.833  -65.465  1.00 80.58  ? 326 PRO C O     1 
ATOM   10662 C CB    . PRO C 1 326 ? -32.857 33.942  -63.245  1.00 78.55  ? 326 PRO C CB    1 
ATOM   10663 C CG    . PRO C 1 326 ? -34.314 34.016  -62.805  1.00 82.20  ? 326 PRO C CG    1 
ATOM   10664 C CD    . PRO C 1 326 ? -34.989 32.792  -63.396  1.00 83.24  ? 326 PRO C CD    1 
ATOM   10665 N N     . VAL C 1 327 ? -31.461 31.247  -64.033  1.00 86.27  ? 327 VAL C N     1 
ATOM   10666 C CA    . VAL C 1 327 ? -30.218 30.485  -63.905  1.00 78.54  ? 327 VAL C CA    1 
ATOM   10667 C C     . VAL C 1 327 ? -30.001 29.642  -65.167  1.00 70.84  ? 327 VAL C C     1 
ATOM   10668 O O     . VAL C 1 327 ? -28.862 29.452  -65.616  1.00 59.47  ? 327 VAL C O     1 
ATOM   10669 C CB    . VAL C 1 327 ? -30.206 29.609  -62.622  1.00 73.29  ? 327 VAL C CB    1 
ATOM   10670 C CG1   . VAL C 1 327 ? -29.135 28.529  -62.651  1.00 66.33  ? 327 VAL C CG1   1 
ATOM   10671 C CG2   . VAL C 1 327 ? -30.028 30.432  -61.354  1.00 69.93  ? 327 VAL C CG2   1 
ATOM   10672 N N     . MET C 1 328 ? -31.107 29.127  -65.718  1.00 63.86  ? 328 MET C N     1 
ATOM   10673 C CA    . MET C 1 328 ? -31.068 28.337  -66.934  1.00 70.09  ? 328 MET C CA    1 
ATOM   10674 C C     . MET C 1 328 ? -30.659 29.207  -68.121  1.00 67.67  ? 328 MET C C     1 
ATOM   10675 O O     . MET C 1 328 ? -29.951 28.728  -68.997  1.00 83.58  ? 328 MET C O     1 
ATOM   10676 C CB    . MET C 1 328 ? -32.416 27.650  -67.183  1.00 72.74  ? 328 MET C CB    1 
ATOM   10677 C CG    . MET C 1 328 ? -32.612 26.459  -66.232  1.00 75.24  ? 328 MET C CG    1 
ATOM   10678 S SD    . MET C 1 328 ? -34.043 25.378  -66.510  1.00 66.30  ? 328 MET C SD    1 
ATOM   10679 C CE    . MET C 1 328 ? -35.380 26.557  -66.660  1.00 63.56  ? 328 MET C CE    1 
ATOM   10680 N N     . ASP C 1 329 ? -31.059 30.485  -68.131  1.00 71.56  ? 329 ASP C N     1 
ATOM   10681 C CA    . ASP C 1 329 ? -30.648 31.406  -69.183  1.00 75.28  ? 329 ASP C CA    1 
ATOM   10682 C C     . ASP C 1 329 ? -29.126 31.562  -69.126  1.00 70.56  ? 329 ASP C C     1 
ATOM   10683 O O     . ASP C 1 329 ? -28.452 31.448  -70.153  1.00 64.19  ? 329 ASP C O     1 
ATOM   10684 C CB    . ASP C 1 329 ? -31.373 32.759  -69.093  1.00 72.80  ? 329 ASP C CB    1 
ATOM   10685 C CG    . ASP C 1 329 ? -32.884 32.689  -69.255  1.00 78.01  ? 329 ASP C CG    1 
ATOM   10686 O OD1   . ASP C 1 329 ? -33.373 31.648  -69.751  1.00 76.22  ? 329 ASP C OD1   1 
ATOM   10687 O OD2   . ASP C 1 329 ? -33.572 33.666  -68.841  1.00 76.42  ? 329 ASP C OD2   1 
ATOM   10688 N N     . THR C 1 330 ? -28.579 31.786  -67.920  1.00 60.12  ? 330 THR C N     1 
ATOM   10689 C CA    . THR C 1 330 ? -27.154 32.056  -67.801  1.00 63.94  ? 330 THR C CA    1 
ATOM   10690 C C     . THR C 1 330 ? -26.352 30.903  -68.402  1.00 63.81  ? 330 THR C C     1 
ATOM   10691 O O     . THR C 1 330 ? -25.383 31.145  -69.135  1.00 55.50  ? 330 THR C O     1 
ATOM   10692 C CB    . THR C 1 330 ? -26.723 32.360  -66.360  1.00 55.90  ? 330 THR C CB    1 
ATOM   10693 O OG1   . THR C 1 330 ? -27.360 33.575  -65.992  1.00 65.12  ? 330 THR C OG1   1 
ATOM   10694 C CG2   . THR C 1 330 ? -25.231 32.568  -66.204  1.00 56.19  ? 330 THR C CG2   1 
ATOM   10695 N N     . LEU C 1 331 ? -26.764 29.670  -68.060  1.00 63.29  ? 331 LEU C N     1 
ATOM   10696 C CA    . LEU C 1 331 ? -25.989 28.487  -68.398  1.00 69.17  ? 331 LEU C CA    1 
ATOM   10697 C C     . LEU C 1 331 ? -26.070 28.234  -69.906  1.00 67.01  ? 331 LEU C C     1 
ATOM   10698 O O     . LEU C 1 331 ? -25.045 28.039  -70.557  1.00 66.99  ? 331 LEU C O     1 
ATOM   10699 C CB    . LEU C 1 331 ? -26.472 27.292  -67.566  1.00 65.22  ? 331 LEU C CB    1 
ATOM   10700 C CG    . LEU C 1 331 ? -26.183 27.366  -66.061  1.00 69.68  ? 331 LEU C CG    1 
ATOM   10701 C CD1   . LEU C 1 331 ? -26.891 26.241  -65.321  1.00 71.21  ? 331 LEU C CD1   1 
ATOM   10702 C CD2   . LEU C 1 331 ? -24.694 27.309  -65.751  1.00 67.97  ? 331 LEU C CD2   1 
ATOM   10703 N N     . TRP C 1 332 ? -27.279 28.290  -70.464  1.00 59.88  ? 332 TRP C N     1 
ATOM   10704 C CA    . TRP C 1 332 ? -27.462 28.135  -71.893  1.00 64.38  ? 332 TRP C CA    1 
ATOM   10705 C C     . TRP C 1 332 ? -26.535 29.054  -72.696  1.00 68.09  ? 332 TRP C C     1 
ATOM   10706 O O     . TRP C 1 332 ? -25.840 28.582  -73.591  1.00 69.38  ? 332 TRP C O     1 
ATOM   10707 C CB    . TRP C 1 332 ? -28.920 28.378  -72.268  1.00 65.18  ? 332 TRP C CB    1 
ATOM   10708 C CG    . TRP C 1 332 ? -29.129 28.137  -73.724  1.00 69.68  ? 332 TRP C CG    1 
ATOM   10709 C CD1   . TRP C 1 332 ? -29.545 29.034  -74.665  1.00 76.34  ? 332 TRP C CD1   1 
ATOM   10710 C CD2   . TRP C 1 332 ? -28.874 26.904  -74.409  1.00 69.26  ? 332 TRP C CD2   1 
ATOM   10711 N NE1   . TRP C 1 332 ? -29.584 28.433  -75.892  1.00 78.54  ? 332 TRP C NE1   1 
ATOM   10712 C CE2   . TRP C 1 332 ? -29.178 27.127  -75.769  1.00 73.46  ? 332 TRP C CE2   1 
ATOM   10713 C CE3   . TRP C 1 332 ? -28.409 25.642  -74.010  1.00 68.21  ? 332 TRP C CE3   1 
ATOM   10714 C CZ2   . TRP C 1 332 ? -29.043 26.123  -76.731  1.00 68.07  ? 332 TRP C CZ2   1 
ATOM   10715 C CZ3   . TRP C 1 332 ? -28.275 24.652  -74.960  1.00 67.96  ? 332 TRP C CZ3   1 
ATOM   10716 C CH2   . TRP C 1 332 ? -28.590 24.892  -76.302  1.00 66.62  ? 332 TRP C CH2   1 
ATOM   10717 N N     . THR C 1 333 ? -26.534 30.358  -72.381  1.00 62.38  ? 333 THR C N     1 
ATOM   10718 C CA    . THR C 1 333 ? -25.575 31.296  -72.938  1.00 62.67  ? 333 THR C CA    1 
ATOM   10719 C C     . THR C 1 333 ? -24.153 30.734  -72.946  1.00 60.28  ? 333 THR C C     1 
ATOM   10720 O O     . THR C 1 333 ? -23.429 30.865  -73.924  1.00 73.61  ? 333 THR C O     1 
ATOM   10721 C CB    . THR C 1 333 ? -25.524 32.594  -72.133  1.00 64.30  ? 333 THR C CB    1 
ATOM   10722 O OG1   . THR C 1 333 ? -26.825 33.149  -72.274  1.00 68.40  ? 333 THR C OG1   1 
ATOM   10723 C CG2   . THR C 1 333 ? -24.456 33.556  -72.608  1.00 61.25  ? 333 THR C CG2   1 
ATOM   10724 N N     . ALA C 1 334 ? -23.709 30.193  -71.826  1.00 55.64  ? 334 ALA C N     1 
ATOM   10725 C CA    . ALA C 1 334 ? -22.343 29.711  -71.744  1.00 61.64  ? 334 ALA C CA    1 
ATOM   10726 C C     . ALA C 1 334 ? -22.176 28.494  -72.641  1.00 57.50  ? 334 ALA C C     1 
ATOM   10727 O O     . ALA C 1 334 ? -21.102 28.291  -73.201  1.00 56.46  ? 334 ALA C O     1 
ATOM   10728 C CB    . ALA C 1 334 ? -21.999 29.348  -70.325  1.00 67.18  ? 334 ALA C CB    1 
ATOM   10729 N N     . ILE C 1 335 ? -23.238 27.688  -72.730  1.00 52.62  ? 335 ILE C N     1 
ATOM   10730 C CA    . ILE C 1 335 ? -23.185 26.421  -73.434  1.00 56.18  ? 335 ILE C CA    1 
ATOM   10731 C C     . ILE C 1 335 ? -23.297 26.657  -74.944  1.00 63.49  ? 335 ILE C C     1 
ATOM   10732 O O     . ILE C 1 335 ? -22.521 26.061  -75.695  1.00 66.98  ? 335 ILE C O     1 
ATOM   10733 C CB    . ILE C 1 335 ? -24.246 25.437  -72.901  1.00 55.59  ? 335 ILE C CB    1 
ATOM   10734 C CG1   . ILE C 1 335 ? -24.012 25.070  -71.434  1.00 55.53  ? 335 ILE C CG1   1 
ATOM   10735 C CG2   . ILE C 1 335 ? -24.280 24.176  -73.744  1.00 60.98  ? 335 ILE C CG2   1 
ATOM   10736 C CD1   . ILE C 1 335 ? -25.027 24.092  -70.868  1.00 54.34  ? 335 ILE C CD1   1 
ATOM   10737 N N     . ARG C 1 336 ? -24.243 27.505  -75.392  1.00 62.08  ? 336 ARG C N     1 
ATOM   10738 C CA    . ARG C 1 336 ? -24.349 27.861  -76.803  1.00 61.51  ? 336 ARG C CA    1 
ATOM   10739 C C     . ARG C 1 336 ? -23.044 28.502  -77.311  1.00 65.42  ? 336 ARG C C     1 
ATOM   10740 O O     . ARG C 1 336 ? -22.481 28.037  -78.305  1.00 61.05  ? 336 ARG C O     1 
ATOM   10741 C CB    . ARG C 1 336 ? -25.586 28.726  -77.052  1.00 67.64  ? 336 ARG C CB    1 
ATOM   10742 C CG    . ARG C 1 336 ? -25.453 29.704  -78.212  1.00 83.55  ? 336 ARG C CG    1 
ATOM   10743 C CD    . ARG C 1 336 ? -26.671 30.594  -78.379  1.00 89.20  ? 336 ARG C CD    1 
ATOM   10744 N NE    . ARG C 1 336 ? -27.750 29.843  -79.006  1.00 92.13  ? 336 ARG C NE    1 
ATOM   10745 C CZ    . ARG C 1 336 ? -27.778 29.480  -80.287  1.00 89.50  ? 336 ARG C CZ    1 
ATOM   10746 N NH1   . ARG C 1 336 ? -26.851 29.914  -81.128  1.00 74.36  ? 336 ARG C NH1   1 
ATOM   10747 N NH2   . ARG C 1 336 ? -28.756 28.704  -80.733  1.00 89.78  ? 336 ARG C NH2   1 
ATOM   10748 N N     . ASP C 1 337 ? -22.502 29.524  -76.628  1.00 64.39  ? 337 ASP C N     1 
ATOM   10749 C CA    . ASP C 1 337 ? -21.362 30.272  -77.166  1.00 64.39  ? 337 ASP C CA    1 
ATOM   10750 C C     . ASP C 1 337 ? -20.104 29.398  -77.225  1.00 57.43  ? 337 ASP C C     1 
ATOM   10751 O O     . ASP C 1 337 ? -19.198 29.663  -78.006  1.00 63.63  ? 337 ASP C O     1 
ATOM   10752 C CB    . ASP C 1 337 ? -21.093 31.572  -76.390  1.00 65.55  ? 337 ASP C CB    1 
ATOM   10753 C CG    . ASP C 1 337 ? -22.312 32.459  -76.155  1.00 66.15  ? 337 ASP C CG    1 
ATOM   10754 O OD1   . ASP C 1 337 ? -23.341 32.264  -76.853  1.00 63.38  ? 337 ASP C OD1   1 
ATOM   10755 O OD2   . ASP C 1 337 ? -22.242 33.312  -75.237  1.00 64.80  ? 337 ASP C OD2   1 
ATOM   10756 N N     . SER C 1 338 ? -20.046 28.357  -76.391  1.00 58.88  ? 338 SER C N     1 
ATOM   10757 C CA    . SER C 1 338 ? -19.006 27.338  -76.444  1.00 53.39  ? 338 SER C CA    1 
ATOM   10758 C C     . SER C 1 338 ? -19.032 26.548  -77.749  1.00 52.46  ? 338 SER C C     1 
ATOM   10759 O O     . SER C 1 338 ? -18.008 26.004  -78.111  1.00 52.22  ? 338 SER C O     1 
ATOM   10760 C CB    . SER C 1 338 ? -19.118 26.374  -75.272  1.00 51.00  ? 338 SER C CB    1 
ATOM   10761 O OG    . SER C 1 338 ? -18.543 26.940  -74.105  1.00 49.70  ? 338 SER C OG    1 
ATOM   10762 N N     . PHE C 1 339 ? -20.189 26.423  -78.419  1.00 55.68  ? 339 PHE C N     1 
ATOM   10763 C CA    . PHE C 1 339 ? -20.298 25.549  -79.580  1.00 61.13  ? 339 PHE C CA    1 
ATOM   10764 C C     . PHE C 1 339 ? -20.644 26.282  -80.893  1.00 67.74  ? 339 PHE C C     1 
ATOM   10765 O O     . PHE C 1 339 ? -20.676 25.634  -81.942  1.00 66.05  ? 339 PHE C O     1 
ATOM   10766 C CB    . PHE C 1 339 ? -21.319 24.450  -79.269  1.00 56.36  ? 339 PHE C CB    1 
ATOM   10767 C CG    . PHE C 1 339 ? -20.836 23.404  -78.295  1.00 57.65  ? 339 PHE C CG    1 
ATOM   10768 C CD1   . PHE C 1 339 ? -19.883 22.467  -78.667  1.00 63.38  ? 339 PHE C CD1   1 
ATOM   10769 C CD2   . PHE C 1 339 ? -21.306 23.376  -76.987  1.00 58.27  ? 339 PHE C CD2   1 
ATOM   10770 C CE1   . PHE C 1 339 ? -19.428 21.512  -77.764  1.00 59.95  ? 339 PHE C CE1   1 
ATOM   10771 C CE2   . PHE C 1 339 ? -20.834 22.442  -76.086  1.00 50.65  ? 339 PHE C CE2   1 
ATOM   10772 C CZ    . PHE C 1 339 ? -19.902 21.507  -76.477  1.00 50.85  ? 339 PHE C CZ    1 
ATOM   10773 N N     . ALA C 1 340 ? -20.840 27.615  -80.880  1.00 66.76  ? 340 ALA C N     1 
ATOM   10774 C CA    . ALA C 1 340 ? -21.593 28.290  -81.936  1.00 71.10  ? 340 ALA C CA    1 
ATOM   10775 C C     . ALA C 1 340 ? -20.797 28.462  -83.237  1.00 75.15  ? 340 ALA C C     1 
ATOM   10776 O O     . ALA C 1 340 ? -21.387 28.700  -84.282  1.00 90.47  ? 340 ALA C O     1 
ATOM   10777 C CB    . ALA C 1 340 ? -22.083 29.630  -81.450  1.00 67.08  ? 340 ALA C CB    1 
ATOM   10778 N N     . ASP C 1 341 ? -19.475 28.315  -83.187  1.00 66.39  ? 341 ASP C N     1 
ATOM   10779 C CA    . ASP C 1 341 ? -18.590 28.627  -84.296  1.00 62.80  ? 341 ASP C CA    1 
ATOM   10780 C C     . ASP C 1 341 ? -18.089 27.355  -84.981  1.00 68.35  ? 341 ASP C C     1 
ATOM   10781 O O     . ASP C 1 341 ? -17.116 27.383  -85.728  1.00 67.53  ? 341 ASP C O     1 
ATOM   10782 C CB    . ASP C 1 341 ? -17.408 29.442  -83.773  1.00 64.09  ? 341 ASP C CB    1 
ATOM   10783 C CG    . ASP C 1 341 ? -16.722 28.827  -82.561  1.00 68.59  ? 341 ASP C CG    1 
ATOM   10784 O OD1   . ASP C 1 341 ? -17.402 28.552  -81.534  1.00 79.10  ? 341 ASP C OD1   1 
ATOM   10785 O OD2   . ASP C 1 341 ? -15.518 28.639  -82.634  1.00 69.35  ? 341 ASP C OD2   1 
ATOM   10786 N N     . ILE C 1 342 ? -18.746 26.227  -84.714  1.00 70.61  ? 342 ILE C N     1 
ATOM   10787 C CA    . ILE C 1 342 ? -18.423 24.973  -85.371  1.00 66.47  ? 342 ILE C CA    1 
ATOM   10788 C C     . ILE C 1 342 ? -19.289 24.872  -86.617  1.00 67.56  ? 342 ILE C C     1 
ATOM   10789 O O     . ILE C 1 342 ? -20.503 24.675  -86.497  1.00 56.41  ? 342 ILE C O     1 
ATOM   10790 C CB    . ILE C 1 342 ? -18.668 23.785  -84.418  1.00 64.51  ? 342 ILE C CB    1 
ATOM   10791 C CG1   . ILE C 1 342 ? -17.586 23.694  -83.344  1.00 61.30  ? 342 ILE C CG1   1 
ATOM   10792 C CG2   . ILE C 1 342 ? -18.819 22.467  -85.164  1.00 63.10  ? 342 ILE C CG2   1 
ATOM   10793 C CD1   . ILE C 1 342 ? -18.032 22.939  -82.105  1.00 67.99  ? 342 ILE C CD1   1 
ATOM   10794 N N     . PRO C 1 343 ? -18.684 24.955  -87.825  1.00 69.74  ? 343 PRO C N     1 
ATOM   10795 C CA    . PRO C 1 343 ? -19.415 24.787  -89.082  1.00 62.11  ? 343 PRO C CA    1 
ATOM   10796 C C     . PRO C 1 343 ? -20.350 23.593  -89.010  1.00 62.15  ? 343 PRO C C     1 
ATOM   10797 O O     . PRO C 1 343 ? -19.915 22.500  -88.661  1.00 74.81  ? 343 PRO C O     1 
ATOM   10798 C CB    . PRO C 1 343 ? -18.326 24.489  -90.118  1.00 62.98  ? 343 PRO C CB    1 
ATOM   10799 C CG    . PRO C 1 343 ? -17.092 25.163  -89.550  1.00 70.16  ? 343 PRO C CG    1 
ATOM   10800 C CD    . PRO C 1 343 ? -17.243 25.134  -88.040  1.00 68.57  ? 343 PRO C CD    1 
ATOM   10801 N N     . GLY C 1 344 ? -21.639 23.830  -89.272  1.00 63.51  ? 344 GLY C N     1 
ATOM   10802 C CA    . GLY C 1 344 ? -22.617 22.757  -89.365  1.00 60.06  ? 344 GLY C CA    1 
ATOM   10803 C C     . GLY C 1 344 ? -23.407 22.532  -88.078  1.00 61.82  ? 344 GLY C C     1 
ATOM   10804 O O     . GLY C 1 344 ? -24.194 21.591  -88.027  1.00 67.15  ? 344 GLY C O     1 
ATOM   10805 N N     . VAL C 1 345 ? -23.210 23.383  -87.054  1.00 63.86  ? 345 VAL C N     1 
ATOM   10806 C CA    . VAL C 1 345 ? -23.850 23.176  -85.760  1.00 64.28  ? 345 VAL C CA    1 
ATOM   10807 C C     . VAL C 1 345 ? -25.282 23.675  -85.821  1.00 63.42  ? 345 VAL C C     1 
ATOM   10808 O O     . VAL C 1 345 ? -25.535 24.763  -86.338  1.00 59.40  ? 345 VAL C O     1 
ATOM   10809 C CB    . VAL C 1 345 ? -23.135 23.871  -84.585  1.00 69.38  ? 345 VAL C CB    1 
ATOM   10810 C CG1   . VAL C 1 345 ? -23.235 25.394  -84.620  1.00 61.91  ? 345 VAL C CG1   1 
ATOM   10811 C CG2   . VAL C 1 345 ? -23.659 23.351  -83.258  1.00 67.22  ? 345 VAL C CG2   1 
ATOM   10812 N N     . LYS C 1 346 ? -26.180 22.882  -85.233  1.00 62.13  ? 346 LYS C N     1 
ATOM   10813 C CA    . LYS C 1 346 ? -27.581 23.255  -85.123  1.00 76.17  ? 346 LYS C CA    1 
ATOM   10814 C C     . LYS C 1 346 ? -28.010 23.108  -83.662  1.00 79.67  ? 346 LYS C C     1 
ATOM   10815 O O     . LYS C 1 346 ? -27.540 22.211  -82.956  1.00 81.71  ? 346 LYS C O     1 
ATOM   10816 C CB    . LYS C 1 346 ? -28.430 22.427  -86.100  1.00 78.79  ? 346 LYS C CB    1 
ATOM   10817 C CG    . LYS C 1 346 ? -28.106 22.663  -87.574  1.00 86.48  ? 346 LYS C CG    1 
ATOM   10818 C CD    . LYS C 1 346 ? -29.011 21.928  -88.552  1.00 97.28  ? 346 LYS C CD    1 
ATOM   10819 C CE    . LYS C 1 346 ? -28.735 22.236  -90.014  1.00 95.10  ? 346 LYS C CE    1 
ATOM   10820 N NZ    . LYS C 1 346 ? -27.553 21.508  -90.541  1.00 86.55  ? 346 LYS C NZ    1 
ATOM   10821 N N     . PHE C 1 347 ? -28.888 24.019  -83.219  1.00 70.65  ? 347 PHE C N     1 
ATOM   10822 C CA    . PHE C 1 347 ? -29.356 24.065  -81.845  1.00 65.59  ? 347 PHE C CA    1 
ATOM   10823 C C     . PHE C 1 347 ? -30.862 23.844  -81.803  1.00 68.80  ? 347 PHE C C     1 
ATOM   10824 O O     . PHE C 1 347 ? -31.613 24.526  -82.485  1.00 66.40  ? 347 PHE C O     1 
ATOM   10825 C CB    . PHE C 1 347 ? -29.003 25.411  -81.214  1.00 60.92  ? 347 PHE C CB    1 
ATOM   10826 C CG    . PHE C 1 347 ? -27.519 25.599  -81.062  1.00 64.80  ? 347 PHE C CG    1 
ATOM   10827 C CD1   . PHE C 1 347 ? -26.827 24.985  -80.029  1.00 61.87  ? 347 PHE C CD1   1 
ATOM   10828 C CD2   . PHE C 1 347 ? -26.807 26.328  -81.994  1.00 61.03  ? 347 PHE C CD2   1 
ATOM   10829 C CE1   . PHE C 1 347 ? -25.460 25.140  -79.905  1.00 54.91  ? 347 PHE C CE1   1 
ATOM   10830 C CE2   . PHE C 1 347 ? -25.441 26.488  -81.863  1.00 57.25  ? 347 PHE C CE2   1 
ATOM   10831 C CZ    . PHE C 1 347 ? -24.772 25.888  -80.823  1.00 62.65  ? 347 PHE C CZ    1 
ATOM   10832 N N     . TYR C 1 348 ? -31.290 22.893  -80.974  1.00 73.72  ? 348 TYR C N     1 
ATOM   10833 C CA    . TYR C 1 348 ? -32.699 22.579  -80.860  1.00 81.17  ? 348 TYR C CA    1 
ATOM   10834 C C     . TYR C 1 348 ? -33.103 22.604  -79.390  1.00 80.57  ? 348 TYR C C     1 
ATOM   10835 O O     . TYR C 1 348 ? -32.379 22.088  -78.541  1.00 83.17  ? 348 TYR C O     1 
ATOM   10836 C CB    . TYR C 1 348 ? -33.008 21.208  -81.469  1.00 80.77  ? 348 TYR C CB    1 
ATOM   10837 C CG    . TYR C 1 348 ? -32.617 21.002  -82.913  1.00 85.67  ? 348 TYR C CG    1 
ATOM   10838 C CD1   . TYR C 1 348 ? -31.308 20.705  -83.261  1.00 87.32  ? 348 TYR C CD1   1 
ATOM   10839 C CD2   . TYR C 1 348 ? -33.558 21.051  -83.935  1.00 80.67  ? 348 TYR C CD2   1 
ATOM   10840 C CE1   . TYR C 1 348 ? -30.939 20.475  -84.579  1.00 90.15  ? 348 TYR C CE1   1 
ATOM   10841 C CE2   . TYR C 1 348 ? -33.203 20.839  -85.260  1.00 76.25  ? 348 TYR C CE2   1 
ATOM   10842 C CZ    . TYR C 1 348 ? -31.892 20.540  -85.581  1.00 86.72  ? 348 TYR C CZ    1 
ATOM   10843 O OH    . TYR C 1 348 ? -31.501 20.310  -86.871  1.00 77.72  ? 348 TYR C OH    1 
ATOM   10844 N N     . PHE C 1 349 ? -34.253 23.240  -79.123  1.00 74.91  ? 349 PHE C N     1 
ATOM   10845 C CA    . PHE C 1 349 ? -35.093 22.928  -77.978  1.00 78.09  ? 349 PHE C CA    1 
ATOM   10846 C C     . PHE C 1 349 ? -36.248 22.049  -78.457  1.00 72.65  ? 349 PHE C C     1 
ATOM   10847 O O     . PHE C 1 349 ? -36.500 21.959  -79.655  1.00 64.81  ? 349 PHE C O     1 
ATOM   10848 C CB    . PHE C 1 349 ? -35.585 24.222  -77.329  1.00 79.72  ? 349 PHE C CB    1 
ATOM   10849 C CG    . PHE C 1 349 ? -34.485 25.064  -76.743  1.00 82.92  ? 349 PHE C CG    1 
ATOM   10850 C CD1   . PHE C 1 349 ? -33.802 24.640  -75.612  1.00 87.82  ? 349 PHE C CD1   1 
ATOM   10851 C CD2   . PHE C 1 349 ? -34.122 26.270  -77.326  1.00 91.70  ? 349 PHE C CD2   1 
ATOM   10852 C CE1   . PHE C 1 349 ? -32.791 25.416  -75.059  1.00 92.44  ? 349 PHE C CE1   1 
ATOM   10853 C CE2   . PHE C 1 349 ? -33.114 27.045  -76.772  1.00 97.73  ? 349 PHE C CE2   1 
ATOM   10854 C CZ    . PHE C 1 349 ? -32.446 26.614  -75.642  1.00 93.41  ? 349 PHE C CZ    1 
ATOM   10855 N N     . PRO C 1 350 ? -36.994 21.368  -77.561  1.00 66.46  ? 350 PRO C N     1 
ATOM   10856 C CA    . PRO C 1 350 ? -38.067 20.467  -77.996  1.00 76.61  ? 350 PRO C CA    1 
ATOM   10857 C C     . PRO C 1 350 ? -39.054 21.041  -79.027  1.00 88.55  ? 350 PRO C C     1 
ATOM   10858 O O     . PRO C 1 350 ? -39.409 20.375  -80.004  1.00 81.76  ? 350 PRO C O     1 
ATOM   10859 C CB    . PRO C 1 350 ? -38.779 20.161  -76.674  1.00 73.99  ? 350 PRO C CB    1 
ATOM   10860 C CG    . PRO C 1 350 ? -37.697 20.295  -75.620  1.00 74.08  ? 350 PRO C CG    1 
ATOM   10861 C CD    . PRO C 1 350 ? -36.857 21.450  -76.101  1.00 69.25  ? 350 PRO C CD    1 
ATOM   10862 N N     . GLU C 1 351 ? -39.488 22.293  -78.813  1.00 99.66  ? 351 GLU C N     1 
ATOM   10863 C CA    . GLU C 1 351 ? -40.453 22.958  -79.682  1.00 92.46  ? 351 GLU C CA    1 
ATOM   10864 C C     . GLU C 1 351 ? -39.885 23.152  -81.088  1.00 89.09  ? 351 GLU C C     1 
ATOM   10865 O O     . GLU C 1 351 ? -40.652 23.425  -82.000  1.00 85.17  ? 351 GLU C O     1 
ATOM   10866 C CB    . GLU C 1 351 ? -40.880 24.316  -79.108  1.00 93.78  ? 351 GLU C CB    1 
ATOM   10867 C CG    . GLU C 1 351 ? -39.735 25.307  -78.894  1.00 101.45 ? 351 GLU C CG    1 
ATOM   10868 C CD    . GLU C 1 351 ? -39.157 25.424  -77.484  1.00 105.42 ? 351 GLU C CD    1 
ATOM   10869 O OE1   . GLU C 1 351 ? -39.035 24.377  -76.792  1.00 90.70  ? 351 GLU C OE1   1 
ATOM   10870 O OE2   . GLU C 1 351 ? -38.788 26.568  -77.083  1.00 92.66  ? 351 GLU C OE2   1 
ATOM   10871 N N     . ASP C 1 352 ? -38.556 23.018  -81.251  1.00 91.45  ? 352 ASP C N     1 
ATOM   10872 C CA    . ASP C 1 352 ? -37.879 23.207  -82.529  1.00 80.85  ? 352 ASP C CA    1 
ATOM   10873 C C     . ASP C 1 352 ? -37.724 21.893  -83.310  1.00 85.44  ? 352 ASP C C     1 
ATOM   10874 O O     . ASP C 1 352 ? -37.094 21.914  -84.364  1.00 98.15  ? 352 ASP C O     1 
ATOM   10875 C CB    . ASP C 1 352 ? -36.458 23.776  -82.367  1.00 81.22  ? 352 ASP C CB    1 
ATOM   10876 C CG    . ASP C 1 352 ? -36.305 25.090  -81.613  1.00 85.08  ? 352 ASP C CG    1 
ATOM   10877 O OD1   . ASP C 1 352 ? -36.974 26.061  -81.998  1.00 81.93  ? 352 ASP C OD1   1 
ATOM   10878 O OD2   . ASP C 1 352 ? -35.460 25.152  -80.684  1.00 80.67  ? 352 ASP C OD2   1 
ATOM   10879 N N     . ARG C 1 353 ? -38.235 20.748  -82.819  1.00 77.64  ? 353 ARG C N     1 
ATOM   10880 C CA    . ARG C 1 353 ? -38.151 19.493  -83.571  1.00 82.06  ? 353 ARG C CA    1 
ATOM   10881 C C     . ARG C 1 353 ? -39.451 19.228  -84.338  1.00 93.18  ? 353 ARG C C     1 
ATOM   10882 O O     . ARG C 1 353 ? -40.514 19.148  -83.724  1.00 95.07  ? 353 ARG C O     1 
ATOM   10883 C CB    . ARG C 1 353 ? -37.932 18.280  -82.653  1.00 81.31  ? 353 ARG C CB    1 
ATOM   10884 C CG    . ARG C 1 353 ? -36.733 18.363  -81.720  1.00 77.44  ? 353 ARG C CG    1 
ATOM   10885 C CD    . ARG C 1 353 ? -35.403 18.300  -82.450  1.00 74.79  ? 353 ARG C CD    1 
ATOM   10886 N NE    . ARG C 1 353 ? -35.131 17.012  -83.077  1.00 66.44  ? 353 ARG C NE    1 
ATOM   10887 C CZ    . ARG C 1 353 ? -34.101 16.781  -83.892  1.00 71.08  ? 353 ARG C CZ    1 
ATOM   10888 N NH1   . ARG C 1 353 ? -33.265 17.758  -84.214  1.00 70.38  ? 353 ARG C NH1   1 
ATOM   10889 N NH2   . ARG C 1 353 ? -33.900 15.570  -84.383  1.00 69.87  ? 353 ARG C NH2   1 
ATOM   10890 N N     . ARG C 1 354 ? -39.359 18.997  -85.659  1.00 103.83 ? 354 ARG C N     1 
ATOM   10891 C CA    . ARG C 1 354 ? -40.539 18.773  -86.494  1.00 102.97 ? 354 ARG C CA    1 
ATOM   10892 C C     . ARG C 1 354 ? -41.136 17.372  -86.272  1.00 99.38  ? 354 ARG C C     1 
ATOM   10893 O O     . ARG C 1 354 ? -42.358 17.238  -86.241  1.00 97.29  ? 354 ARG C O     1 
ATOM   10894 C CB    . ARG C 1 354 ? -40.252 19.091  -87.969  1.00 94.87  ? 354 ARG C CB    1 
ATOM   10895 C CG    . ARG C 1 354 ? -39.067 18.366  -88.590  1.00 100.44 ? 354 ARG C CG    1 
ATOM   10896 C CD    . ARG C 1 354 ? -38.760 18.882  -89.989  1.00 104.07 ? 354 ARG C CD    1 
ATOM   10897 N NE    . ARG C 1 354 ? -37.637 18.193  -90.627  1.00 110.99 ? 354 ARG C NE    1 
ATOM   10898 C CZ    . ARG C 1 354 ? -37.674 16.979  -91.191  1.00 110.42 ? 354 ARG C CZ    1 
ATOM   10899 N NH1   . ARG C 1 354 ? -38.812 16.319  -91.335  1.00 104.43 ? 354 ARG C NH1   1 
ATOM   10900 N NH2   . ARG C 1 354 ? -36.556 16.431  -91.639  1.00 103.63 ? 354 ARG C NH2   1 
ATOM   10901 N N     . HIS C 1 355 ? -40.308 16.331  -86.087  1.00 91.60  ? 355 HIS C N     1 
ATOM   10902 C CA    . HIS C 1 355 ? -40.817 15.009  -85.730  1.00 98.36  ? 355 HIS C CA    1 
ATOM   10903 C C     . HIS C 1 355 ? -41.347 15.036  -84.291  1.00 100.43 ? 355 HIS C C     1 
ATOM   10904 O O     . HIS C 1 355 ? -40.742 15.657  -83.420  1.00 99.29  ? 355 HIS C O     1 
ATOM   10905 C CB    . HIS C 1 355 ? -39.756 13.906  -85.904  1.00 100.22 ? 355 HIS C CB    1 
ATOM   10906 C CG    . HIS C 1 355 ? -39.147 13.741  -87.271  1.00 104.96 ? 355 HIS C CG    1 
ATOM   10907 N ND1   . HIS C 1 355 ? -39.491 12.707  -88.120  1.00 94.92  ? 355 HIS C ND1   1 
ATOM   10908 C CD2   . HIS C 1 355 ? -38.196 14.453  -87.925  1.00 98.71  ? 355 HIS C CD2   1 
ATOM   10909 C CE1   . HIS C 1 355 ? -38.780 12.803  -89.242  1.00 97.75  ? 355 HIS C CE1   1 
ATOM   10910 N NE2   . HIS C 1 355 ? -37.985 13.854  -89.145  1.00 90.87  ? 355 HIS C NE2   1 
ATOM   10911 N N     . LYS C 1 356 ? -42.489 14.371  -84.051  1.00 95.68  ? 356 LYS C N     1 
ATOM   10912 C CA    . LYS C 1 356 ? -43.146 14.389  -82.748  1.00 104.71 ? 356 LYS C CA    1 
ATOM   10913 C C     . LYS C 1 356 ? -42.881 13.082  -82.002  1.00 98.73  ? 356 LYS C C     1 
ATOM   10914 O O     . LYS C 1 356 ? -43.108 12.988  -80.802  1.00 88.57  ? 356 LYS C O     1 
ATOM   10915 C CB    . LYS C 1 356 ? -44.659 14.637  -82.873  1.00 117.00 ? 356 LYS C CB    1 
ATOM   10916 C CG    . LYS C 1 356 ? -45.100 16.081  -83.122  1.00 119.76 ? 356 LYS C CG    1 
ATOM   10917 C CD    . LYS C 1 356 ? -46.536 16.400  -82.688  1.00 114.67 ? 356 LYS C CD    1 
ATOM   10918 C CE    . LYS C 1 356 ? -47.614 15.551  -83.338  1.00 112.68 ? 356 LYS C CE    1 
ATOM   10919 N NZ    . LYS C 1 356 ? -47.850 15.935  -84.749  1.00 108.14 ? 356 LYS C NZ    1 
ATOM   10920 N N     . VAL C 1 357 ? -42.475 12.042  -82.727  1.00 104.83 ? 357 VAL C N     1 
ATOM   10921 C CA    . VAL C 1 357 ? -41.767 10.926  -82.127  1.00 109.70 ? 357 VAL C CA    1 
ATOM   10922 C C     . VAL C 1 357 ? -40.305 11.151  -82.506  1.00 116.46 ? 357 VAL C C     1 
ATOM   10923 O O     . VAL C 1 357 ? -39.923 11.000  -83.666  1.00 118.72 ? 357 VAL C O     1 
ATOM   10924 C CB    . VAL C 1 357 ? -42.332 9.558   -82.581  1.00 108.83 ? 357 VAL C CB    1 
ATOM   10925 C CG1   . VAL C 1 357 ? -41.489 8.370   -82.120  1.00 104.32 ? 357 VAL C CG1   1 
ATOM   10926 C CG2   . VAL C 1 357 ? -43.774 9.380   -82.131  1.00 106.35 ? 357 VAL C CG2   1 
ATOM   10927 N N     . ASP C 1 358 ? -39.519 11.602  -81.523  1.00 118.66 ? 358 ASP C N     1 
ATOM   10928 C CA    . ASP C 1 358 ? -38.184 12.119  -81.774  1.00 114.07 ? 358 ASP C CA    1 
ATOM   10929 C C     . ASP C 1 358 ? -37.253 11.628  -80.669  1.00 112.09 ? 358 ASP C C     1 
ATOM   10930 O O     . ASP C 1 358 ? -37.706 11.298  -79.569  1.00 106.67 ? 358 ASP C O     1 
ATOM   10931 C CB    . ASP C 1 358 ? -38.203 13.651  -81.855  1.00 107.90 ? 358 ASP C CB    1 
ATOM   10932 C CG    . ASP C 1 358 ? -36.972 14.264  -82.496  1.00 95.17  ? 358 ASP C CG    1 
ATOM   10933 O OD1   . ASP C 1 358 ? -36.623 13.842  -83.604  1.00 91.96  ? 358 ASP C OD1   1 
ATOM   10934 O OD2   . ASP C 1 358 ? -36.397 15.185  -81.897  1.00 100.12 ? 358 ASP C OD2   1 
ATOM   10935 N N     . LEU C 1 359 ? -35.957 11.575  -80.997  1.00 99.75  ? 359 LEU C N     1 
ATOM   10936 C CA    . LEU C 1 359 ? -34.911 11.310  -80.026  1.00 97.16  ? 359 LEU C CA    1 
ATOM   10937 C C     . LEU C 1 359 ? -35.076 12.225  -78.807  1.00 92.55  ? 359 LEU C C     1 
ATOM   10938 O O     . LEU C 1 359 ? -35.267 11.756  -77.685  1.00 78.77  ? 359 LEU C O     1 
ATOM   10939 C CB    . LEU C 1 359 ? -33.562 11.534  -80.719  1.00 102.22 ? 359 LEU C CB    1 
ATOM   10940 C CG    . LEU C 1 359 ? -32.353 11.629  -79.790  1.00 100.57 ? 359 LEU C CG    1 
ATOM   10941 C CD1   . LEU C 1 359 ? -31.957 10.253  -79.270  1.00 92.38  ? 359 LEU C CD1   1 
ATOM   10942 C CD2   . LEU C 1 359 ? -31.191 12.309  -80.495  1.00 107.75 ? 359 LEU C CD2   1 
ATOM   10943 N N     . LEU C 1 360 ? -34.999 13.542  -79.026  1.00 84.22  ? 360 LEU C N     1 
ATOM   10944 C CA    . LEU C 1 360 ? -35.029 14.490  -77.926  1.00 87.57  ? 360 LEU C CA    1 
ATOM   10945 C C     . LEU C 1 360 ? -36.153 14.148  -76.946  1.00 88.24  ? 360 LEU C C     1 
ATOM   10946 O O     . LEU C 1 360 ? -35.917 14.046  -75.749  1.00 89.08  ? 360 LEU C O     1 
ATOM   10947 C CB    . LEU C 1 360 ? -35.187 15.909  -78.478  1.00 84.68  ? 360 LEU C CB    1 
ATOM   10948 C CG    . LEU C 1 360 ? -35.018 17.035  -77.456  1.00 86.81  ? 360 LEU C CG    1 
ATOM   10949 C CD1   . LEU C 1 360 ? -33.871 16.741  -76.490  1.00 95.26  ? 360 LEU C CD1   1 
ATOM   10950 C CD2   . LEU C 1 360 ? -34.767 18.374  -78.147  1.00 79.30  ? 360 LEU C CD2   1 
ATOM   10951 N N     . LEU C 1 361 ? -37.374 13.945  -77.443  1.00 86.85  ? 361 LEU C N     1 
ATOM   10952 C CA    . LEU C 1 361 ? -38.513 13.860  -76.545  1.00 87.03  ? 361 LEU C CA    1 
ATOM   10953 C C     . LEU C 1 361 ? -38.375 12.630  -75.655  1.00 76.28  ? 361 LEU C C     1 
ATOM   10954 O O     . LEU C 1 361 ? -38.569 12.737  -74.452  1.00 77.31  ? 361 LEU C O     1 
ATOM   10955 C CB    . LEU C 1 361 ? -39.828 13.882  -77.338  1.00 91.14  ? 361 LEU C CB    1 
ATOM   10956 C CG    . LEU C 1 361 ? -40.043 15.115  -78.226  1.00 97.14  ? 361 LEU C CG    1 
ATOM   10957 C CD1   . LEU C 1 361 ? -41.416 15.082  -78.874  1.00 92.47  ? 361 LEU C CD1   1 
ATOM   10958 C CD2   . LEU C 1 361 ? -39.859 16.423  -77.460  1.00 97.08  ? 361 LEU C CD2   1 
ATOM   10959 N N     . HIS C 1 362 ? -37.979 11.486  -76.222  1.00 86.83  ? 362 HIS C N     1 
ATOM   10960 C CA    . HIS C 1 362 ? -37.831 10.266  -75.436  1.00 91.65  ? 362 HIS C CA    1 
ATOM   10961 C C     . HIS C 1 362 ? -36.714 10.448  -74.414  1.00 80.67  ? 362 HIS C C     1 
ATOM   10962 O O     . HIS C 1 362 ? -36.847 9.974   -73.303  1.00 74.52  ? 362 HIS C O     1 
ATOM   10963 C CB    . HIS C 1 362 ? -37.689 9.010   -76.314  1.00 99.91  ? 362 HIS C CB    1 
ATOM   10964 C CG    . HIS C 1 362 ? -38.967 8.648   -77.030  1.00 126.40 ? 362 HIS C CG    1 
ATOM   10965 N ND1   . HIS C 1 362 ? -40.186 8.552   -76.382  1.00 130.11 ? 362 HIS C ND1   1 
ATOM   10966 C CD2   . HIS C 1 362 ? -39.227 8.404   -78.329  1.00 115.14 ? 362 HIS C CD2   1 
ATOM   10967 C CE1   . HIS C 1 362 ? -41.135 8.252   -77.258  1.00 122.85 ? 362 HIS C CE1   1 
ATOM   10968 N NE2   . HIS C 1 362 ? -40.575 8.161   -78.447  1.00 123.36 ? 362 HIS C NE2   1 
ATOM   10969 N N     . ARG C 1 363 ? -35.653 11.177  -74.777  1.00 82.78  ? 363 ARG C N     1 
ATOM   10970 C CA    . ARG C 1 363 ? -34.502 11.378  -73.906  1.00 82.07  ? 363 ARG C CA    1 
ATOM   10971 C C     . ARG C 1 363 ? -34.786 12.457  -72.858  1.00 78.82  ? 363 ARG C C     1 
ATOM   10972 O O     . ARG C 1 363 ? -34.139 12.455  -71.810  1.00 75.27  ? 363 ARG C O     1 
ATOM   10973 C CB    . ARG C 1 363 ? -33.238 11.729  -74.709  1.00 83.26  ? 363 ARG C CB    1 
ATOM   10974 C CG    . ARG C 1 363 ? -32.772 10.616  -75.641  1.00 91.66  ? 363 ARG C CG    1 
ATOM   10975 C CD    . ARG C 1 363 ? -31.276 10.377  -75.685  1.00 93.90  ? 363 ARG C CD    1 
ATOM   10976 N NE    . ARG C 1 363 ? -30.796 10.012  -74.361  1.00 115.16 ? 363 ARG C NE    1 
ATOM   10977 C CZ    . ARG C 1 363 ? -31.104 8.887   -73.717  1.00 119.74 ? 363 ARG C CZ    1 
ATOM   10978 N NH1   . ARG C 1 363 ? -31.700 7.900   -74.366  1.00 114.19 ? 363 ARG C NH1   1 
ATOM   10979 N NH2   . ARG C 1 363 ? -30.771 8.735   -72.440  1.00 110.69 ? 363 ARG C NH2   1 
ATOM   10980 N N     . ALA C 1 364 ? -35.748 13.355  -73.132  1.00 68.70  ? 364 ALA C N     1 
ATOM   10981 C CA    . ALA C 1 364 ? -36.102 14.425  -72.208  1.00 62.83  ? 364 ALA C CA    1 
ATOM   10982 C C     . ALA C 1 364 ? -36.764 13.851  -70.952  1.00 64.61  ? 364 ALA C C     1 
ATOM   10983 O O     . ALA C 1 364 ? -36.673 14.439  -69.873  1.00 64.06  ? 364 ALA C O     1 
ATOM   10984 C CB    . ALA C 1 364 ? -37.008 15.424  -72.888  1.00 55.74  ? 364 ALA C CB    1 
ATOM   10985 N N     . GLU C 1 365 ? -37.454 12.720  -71.130  1.00 57.56  ? 365 GLU C N     1 
ATOM   10986 C CA    . GLU C 1 365 ? -38.068 11.967  -70.052  1.00 63.52  ? 365 GLU C CA    1 
ATOM   10987 C C     . GLU C 1 365 ? -36.994 11.441  -69.094  1.00 58.61  ? 365 GLU C C     1 
ATOM   10988 O O     . GLU C 1 365 ? -37.048 11.698  -67.902  1.00 50.69  ? 365 GLU C O     1 
ATOM   10989 C CB    . GLU C 1 365 ? -38.854 10.796  -70.656  1.00 72.46  ? 365 GLU C CB    1 
ATOM   10990 C CG    . GLU C 1 365 ? -40.000 11.211  -71.569  1.00 74.16  ? 365 GLU C CG    1 
ATOM   10991 C CD    . GLU C 1 365 ? -41.159 11.848  -70.827  1.00 80.98  ? 365 GLU C CD    1 
ATOM   10992 O OE1   . GLU C 1 365 ? -41.269 13.103  -70.845  1.00 84.84  ? 365 GLU C OE1   1 
ATOM   10993 O OE2   . GLU C 1 365 ? -41.942 11.087  -70.228  1.00 82.89  ? 365 GLU C OE2   1 
ATOM   10994 N N     . THR C 1 366 ? -36.021 10.702  -69.641  1.00 59.76  ? 366 THR C N     1 
ATOM   10995 C CA    . THR C 1 366 ? -34.919 10.118  -68.891  1.00 59.48  ? 366 THR C CA    1 
ATOM   10996 C C     . THR C 1 366 ? -34.219 11.176  -68.041  1.00 57.71  ? 366 THR C C     1 
ATOM   10997 O O     . THR C 1 366 ? -33.935 10.924  -66.869  1.00 57.54  ? 366 THR C O     1 
ATOM   10998 C CB    . THR C 1 366 ? -33.848 9.506   -69.813  1.00 62.66  ? 366 THR C CB    1 
ATOM   10999 O OG1   . THR C 1 366 ? -34.436 8.858   -70.943  1.00 57.59  ? 366 THR C OG1   1 
ATOM   11000 C CG2   . THR C 1 366 ? -32.973 8.504   -69.088  1.00 61.67  ? 366 THR C CG2   1 
ATOM   11001 N N     . MET C 1 367 ? -33.929 12.339  -68.656  1.00 55.70  ? 367 MET C N     1 
ATOM   11002 C CA    . MET C 1 367 ? -33.119 13.379  -68.045  1.00 49.73  ? 367 MET C CA    1 
ATOM   11003 C C     . MET C 1 367 ? -33.915 14.190  -67.022  1.00 50.31  ? 367 MET C C     1 
ATOM   11004 O O     . MET C 1 367 ? -33.380 15.141  -66.462  1.00 51.05  ? 367 MET C O     1 
ATOM   11005 C CB    . MET C 1 367 ? -32.564 14.306  -69.118  1.00 47.03  ? 367 MET C CB    1 
ATOM   11006 C CG    . MET C 1 367 ? -31.498 13.627  -69.986  1.00 51.95  ? 367 MET C CG    1 
ATOM   11007 S SD    . MET C 1 367 ? -30.640 14.780  -71.148  1.00 57.29  ? 367 MET C SD    1 
ATOM   11008 C CE    . MET C 1 367 ? -32.054 15.534  -71.955  1.00 63.70  ? 367 MET C CE    1 
ATOM   11009 N N     . LYS C 1 368 ? -35.186 13.833  -66.784  1.00 49.21  ? 368 LYS C N     1 
ATOM   11010 C CA    . LYS C 1 368 ? -35.869 14.251  -65.567  1.00 59.33  ? 368 LYS C CA    1 
ATOM   11011 C C     . LYS C 1 368 ? -36.209 13.051  -64.662  1.00 56.09  ? 368 LYS C C     1 
ATOM   11012 O O     . LYS C 1 368 ? -37.026 13.144  -63.753  1.00 51.45  ? 368 LYS C O     1 
ATOM   11013 C CB    . LYS C 1 368 ? -37.086 15.102  -65.927  1.00 60.47  ? 368 LYS C CB    1 
ATOM   11014 C CG    . LYS C 1 368 ? -38.260 14.370  -66.551  1.00 67.63  ? 368 LYS C CG    1 
ATOM   11015 C CD    . LYS C 1 368 ? -39.497 15.249  -66.693  1.00 84.14  ? 368 LYS C CD    1 
ATOM   11016 C CE    . LYS C 1 368 ? -40.694 14.498  -67.252  1.00 95.85  ? 368 LYS C CE    1 
ATOM   11017 N NZ    . LYS C 1 368 ? -41.697 15.410  -67.854  1.00 94.00  ? 368 LYS C NZ    1 
ATOM   11018 N N     . GLY C 1 369 ? -35.530 11.925  -64.869  1.00 57.36  ? 369 GLY C N     1 
ATOM   11019 C CA    . GLY C 1 369 ? -35.677 10.759  -64.011  1.00 57.54  ? 369 GLY C CA    1 
ATOM   11020 C C     . GLY C 1 369 ? -37.042 10.082  -64.125  1.00 56.02  ? 369 GLY C C     1 
ATOM   11021 O O     . GLY C 1 369 ? -37.546 9.613   -63.113  1.00 51.28  ? 369 GLY C O     1 
ATOM   11022 N N     . VAL C 1 370 ? -37.618 10.018  -65.347  1.00 55.57  ? 370 VAL C N     1 
ATOM   11023 C CA    . VAL C 1 370 ? -38.798 9.203   -65.613  1.00 53.83  ? 370 VAL C CA    1 
ATOM   11024 C C     . VAL C 1 370 ? -38.392 7.860   -66.218  1.00 52.72  ? 370 VAL C C     1 
ATOM   11025 O O     . VAL C 1 370 ? -37.893 7.759   -67.330  1.00 55.03  ? 370 VAL C O     1 
ATOM   11026 C CB    . VAL C 1 370 ? -39.827 9.907   -66.517  1.00 62.51  ? 370 VAL C CB    1 
ATOM   11027 C CG1   . VAL C 1 370 ? -41.095 9.074   -66.709  1.00 61.19  ? 370 VAL C CG1   1 
ATOM   11028 C CG2   . VAL C 1 370 ? -40.186 11.278  -65.975  1.00 74.99  ? 370 VAL C CG2   1 
ATOM   11029 N N     . PRO C 1 371 ? -38.676 6.734   -65.546  1.00 57.98  ? 371 PRO C N     1 
ATOM   11030 C CA    . PRO C 1 371 ? -38.293 5.439   -66.094  1.00 61.43  ? 371 PRO C CA    1 
ATOM   11031 C C     . PRO C 1 371 ? -39.157 5.092   -67.305  1.00 61.54  ? 371 PRO C C     1 
ATOM   11032 O O     . PRO C 1 371 ? -40.365 5.312   -67.296  1.00 58.54  ? 371 PRO C O     1 
ATOM   11033 C CB    . PRO C 1 371 ? -38.543 4.507   -64.911  1.00 56.79  ? 371 PRO C CB    1 
ATOM   11034 C CG    . PRO C 1 371 ? -39.720 5.150   -64.219  1.00 58.19  ? 371 PRO C CG    1 
ATOM   11035 C CD    . PRO C 1 371 ? -39.466 6.637   -64.314  1.00 57.34  ? 371 PRO C CD    1 
ATOM   11036 N N     . LYS C 1 372 ? -38.499 4.583   -68.346  1.00 68.79  ? 372 LYS C N     1 
ATOM   11037 C CA    . LYS C 1 372 ? -39.147 4.099   -69.548  1.00 74.05  ? 372 LYS C CA    1 
ATOM   11038 C C     . LYS C 1 372 ? -38.465 2.805   -69.982  1.00 89.72  ? 372 LYS C C     1 
ATOM   11039 O O     . LYS C 1 372 ? -37.509 2.350   -69.353  1.00 84.48  ? 372 LYS C O     1 
ATOM   11040 C CB    . LYS C 1 372 ? -39.036 5.156   -70.648  1.00 75.57  ? 372 LYS C CB    1 
ATOM   11041 C CG    . LYS C 1 372 ? -39.779 6.452   -70.374  1.00 78.69  ? 372 LYS C CG    1 
ATOM   11042 C CD    . LYS C 1 372 ? -41.291 6.355   -70.533  1.00 80.61  ? 372 LYS C CD    1 
ATOM   11043 C CE    . LYS C 1 372 ? -42.023 7.458   -69.796  1.00 73.87  ? 372 LYS C CE    1 
ATOM   11044 N NZ    . LYS C 1 372 ? -43.264 7.879   -70.480  1.00 67.17  ? 372 LYS C NZ    1 
ATOM   11045 N N     . LEU C 1 373 ? -38.970 2.232   -71.078  1.00 114.49 ? 373 LEU C N     1 
ATOM   11046 C CA    . LEU C 1 373 ? -38.389 1.043   -71.682  1.00 119.81 ? 373 LEU C CA    1 
ATOM   11047 C C     . LEU C 1 373 ? -37.855 1.354   -73.082  1.00 112.26 ? 373 LEU C C     1 
ATOM   11048 O O     . LEU C 1 373 ? -37.159 0.531   -73.669  1.00 113.01 ? 373 LEU C O     1 
ATOM   11049 C CB    . LEU C 1 373 ? -39.463 -0.053  -71.698  1.00 133.44 ? 373 LEU C CB    1 
ATOM   11050 C CG    . LEU C 1 373 ? -40.805 0.289   -72.350  1.00 155.36 ? 373 LEU C CG    1 
ATOM   11051 C CD1   . LEU C 1 373 ? -40.983 -0.463  -73.669  1.00 157.99 ? 373 LEU C CD1   1 
ATOM   11052 C CD2   . LEU C 1 373 ? -41.957 -0.007  -71.392  1.00 142.81 ? 373 LEU C CD2   1 
ATOM   11053 N N     . THR C 1 374 ? -38.104 2.577   -73.572  1.00 115.18 ? 374 THR C N     1 
ATOM   11054 C CA    . THR C 1 374 ? -38.149 2.846   -75.002  1.00 115.09 ? 374 THR C CA    1 
ATOM   11055 C C     . THR C 1 374 ? -36.740 3.000   -75.602  1.00 115.13 ? 374 THR C C     1 
ATOM   11056 O O     . THR C 1 374 ? -36.614 3.066   -76.824  1.00 120.12 ? 374 THR C O     1 
ATOM   11057 C CB    . THR C 1 374 ? -39.105 4.018   -75.311  1.00 118.78 ? 374 THR C CB    1 
ATOM   11058 O OG1   . THR C 1 374 ? -38.611 5.255   -74.794  1.00 122.86 ? 374 THR C OG1   1 
ATOM   11059 C CG2   . THR C 1 374 ? -40.507 3.822   -74.765  1.00 113.26 ? 374 THR C CG2   1 
ATOM   11060 N N     . GLU C 1 375 ? -35.666 3.016   -74.791  1.00 106.75 ? 375 GLU C N     1 
ATOM   11061 C CA    . GLU C 1 375 ? -34.326 3.072   -75.365  1.00 111.70 ? 375 GLU C CA    1 
ATOM   11062 C C     . GLU C 1 375 ? -34.031 1.735   -76.041  1.00 121.75 ? 375 GLU C C     1 
ATOM   11063 O O     . GLU C 1 375 ? -33.358 1.713   -77.068  1.00 133.63 ? 375 GLU C O     1 
ATOM   11064 C CB    . GLU C 1 375 ? -33.263 3.445   -74.325  1.00 116.36 ? 375 GLU C CB    1 
ATOM   11065 C CG    . GLU C 1 375 ? -31.799 3.204   -74.749  1.00 116.53 ? 375 GLU C CG    1 
ATOM   11066 C CD    . GLU C 1 375 ? -30.980 4.312   -75.419  1.00 109.89 ? 375 GLU C CD    1 
ATOM   11067 O OE1   . GLU C 1 375 ? -31.565 5.321   -75.888  1.00 97.58  ? 375 GLU C OE1   1 
ATOM   11068 O OE2   . GLU C 1 375 ? -29.721 4.175   -75.453  1.00 91.67  ? 375 GLU C OE2   1 
ATOM   11069 N N     . PHE C 1 376 ? -34.600 0.646   -75.497  1.00 120.80 ? 376 PHE C N     1 
ATOM   11070 C CA    . PHE C 1 376 ? -34.360 -0.720  -75.960  1.00 111.65 ? 376 PHE C CA    1 
ATOM   11071 C C     . PHE C 1 376 ? -34.696 -0.943  -77.439  1.00 89.17  ? 376 PHE C C     1 
ATOM   11072 O O     . PHE C 1 376 ? -34.548 -2.065  -77.913  1.00 74.17  ? 376 PHE C O     1 
ATOM   11073 C CB    . PHE C 1 376 ? -35.163 -1.721  -75.118  1.00 115.38 ? 376 PHE C CB    1 
ATOM   11074 C CG    . PHE C 1 376 ? -34.447 -2.240  -73.896  1.00 125.21 ? 376 PHE C CG    1 
ATOM   11075 C CD1   . PHE C 1 376 ? -33.847 -1.368  -72.996  1.00 115.10 ? 376 PHE C CD1   1 
ATOM   11076 C CD2   . PHE C 1 376 ? -34.381 -3.607  -73.640  1.00 133.90 ? 376 PHE C CD2   1 
ATOM   11077 C CE1   . PHE C 1 376 ? -33.176 -1.853  -71.884  1.00 118.26 ? 376 PHE C CE1   1 
ATOM   11078 C CE2   . PHE C 1 376 ? -33.719 -4.092  -72.521  1.00 132.48 ? 376 PHE C CE2   1 
ATOM   11079 C CZ    . PHE C 1 376 ? -33.110 -3.213  -71.649  1.00 133.00 ? 376 PHE C CZ    1 
ATOM   11080 N N     . ASN C 1 377 ? -35.115 0.105   -78.169  1.00 92.61  ? 377 ASN C N     1 
ATOM   11081 C CA    . ASN C 1 377 ? -35.497 -0.011  -79.574  1.00 93.69  ? 377 ASN C CA    1 
ATOM   11082 C C     . ASN C 1 377 ? -34.281 -0.207  -80.486  1.00 82.48  ? 377 ASN C C     1 
ATOM   11083 O O     . ASN C 1 377 ? -34.414 -0.771  -81.564  1.00 82.82  ? 377 ASN C O     1 
ATOM   11084 C CB    . ASN C 1 377 ? -36.268 1.219   -80.078  1.00 97.43  ? 377 ASN C CB    1 
ATOM   11085 C CG    . ASN C 1 377 ? -37.622 1.443   -79.428  1.00 90.79  ? 377 ASN C CG    1 
ATOM   11086 O OD1   . ASN C 1 377 ? -38.334 0.503   -79.086  1.00 84.72  ? 377 ASN C OD1   1 
ATOM   11087 N ND2   . ASN C 1 377 ? -38.003 2.701   -79.274  1.00 86.85  ? 377 ASN C ND2   1 
ATOM   11088 N N     . PHE C 1 378 ? -33.098 0.272   -80.079  1.00 82.75  ? 378 PHE C N     1 
ATOM   11089 C CA    . PHE C 1 378 ? -31.914 0.202   -80.926  1.00 83.14  ? 378 PHE C CA    1 
ATOM   11090 C C     . PHE C 1 378 ? -31.534 -1.250  -81.211  1.00 82.08  ? 378 PHE C C     1 
ATOM   11091 O O     . PHE C 1 378 ? -30.755 -1.503  -82.126  1.00 89.10  ? 378 PHE C O     1 
ATOM   11092 C CB    . PHE C 1 378 ? -30.751 1.005   -80.327  1.00 84.79  ? 378 PHE C CB    1 
ATOM   11093 C CG    . PHE C 1 378 ? -30.175 0.528   -79.011  1.00 95.12  ? 378 PHE C CG    1 
ATOM   11094 C CD1   . PHE C 1 378 ? -29.562 -0.714  -78.896  1.00 86.95  ? 378 PHE C CD1   1 
ATOM   11095 C CD2   . PHE C 1 378 ? -30.178 1.355   -77.892  1.00 94.88  ? 378 PHE C CD2   1 
ATOM   11096 C CE1   . PHE C 1 378 ? -29.002 -1.128  -77.693  1.00 81.78  ? 378 PHE C CE1   1 
ATOM   11097 C CE2   . PHE C 1 378 ? -29.618 0.938   -76.692  1.00 83.44  ? 378 PHE C CE2   1 
ATOM   11098 C CZ    . PHE C 1 378 ? -29.031 -0.303  -76.595  1.00 79.62  ? 378 PHE C CZ    1 
ATOM   11099 N N     . LEU C 1 379 ? -32.085 -2.188  -80.426  1.00 82.04  ? 379 LEU C N     1 
ATOM   11100 C CA    . LEU C 1 379 ? -31.966 -3.617  -80.685  1.00 87.90  ? 379 LEU C CA    1 
ATOM   11101 C C     . LEU C 1 379 ? -32.570 -4.011  -82.042  1.00 87.32  ? 379 LEU C C     1 
ATOM   11102 O O     . LEU C 1 379 ? -32.053 -4.937  -82.668  1.00 98.99  ? 379 LEU C O     1 
ATOM   11103 C CB    . LEU C 1 379 ? -32.637 -4.393  -79.541  1.00 89.81  ? 379 LEU C CB    1 
ATOM   11104 C CG    . LEU C 1 379 ? -31.969 -4.322  -78.163  1.00 86.39  ? 379 LEU C CG    1 
ATOM   11105 C CD1   . LEU C 1 379 ? -32.737 -5.156  -77.147  1.00 83.94  ? 379 LEU C CD1   1 
ATOM   11106 C CD2   . LEU C 1 379 ? -30.516 -4.786  -78.204  1.00 93.36  ? 379 LEU C CD2   1 
ATOM   11107 N N     . ASN C 1 380 ? -33.634 -3.311  -82.492  1.00 85.37  ? 380 ASN C N     1 
ATOM   11108 C CA    . ASN C 1 380 ? -34.377 -3.636  -83.710  1.00 88.41  ? 380 ASN C CA    1 
ATOM   11109 C C     . ASN C 1 380 ? -33.574 -3.344  -84.976  1.00 87.96  ? 380 ASN C C     1 
ATOM   11110 O O     . ASN C 1 380 ? -33.902 -3.866  -86.043  1.00 101.87 ? 380 ASN C O     1 
ATOM   11111 C CB    . ASN C 1 380 ? -35.679 -2.839  -83.876  1.00 93.89  ? 380 ASN C CB    1 
ATOM   11112 C CG    . ASN C 1 380 ? -36.716 -3.136  -82.814  1.00 96.48  ? 380 ASN C CG    1 
ATOM   11113 O OD1   . ASN C 1 380 ? -37.083 -4.289  -82.609  1.00 83.58  ? 380 ASN C OD1   1 
ATOM   11114 N ND2   . ASN C 1 380 ? -37.189 -2.105  -82.130  1.00 102.04 ? 380 ASN C ND2   1 
ATOM   11115 N N     . TRP C 1 381 ? -32.585 -2.447  -84.881  1.00 71.97  ? 381 TRP C N     1 
ATOM   11116 C CA    . TRP C 1 381 ? -31.615 -2.289  -85.948  1.00 74.18  ? 381 TRP C CA    1 
ATOM   11117 C C     . TRP C 1 381 ? -31.159 -3.679  -86.380  1.00 92.87  ? 381 TRP C C     1 
ATOM   11118 O O     . TRP C 1 381 ? -30.841 -4.514  -85.533  1.00 122.20 ? 381 TRP C O     1 
ATOM   11119 C CB    . TRP C 1 381 ? -30.428 -1.467  -85.448  1.00 72.41  ? 381 TRP C CB    1 
ATOM   11120 C CG    . TRP C 1 381 ? -29.632 -0.829  -86.537  1.00 65.98  ? 381 TRP C CG    1 
ATOM   11121 C CD1   . TRP C 1 381 ? -28.442 -1.238  -87.074  1.00 67.09  ? 381 TRP C CD1   1 
ATOM   11122 C CD2   . TRP C 1 381 ? -29.955 0.406   -87.183  1.00 65.26  ? 381 TRP C CD2   1 
ATOM   11123 N NE1   . TRP C 1 381 ? -28.021 -0.357  -88.042  1.00 55.28  ? 381 TRP C NE1   1 
ATOM   11124 C CE2   . TRP C 1 381 ? -28.929 0.664   -88.123  1.00 56.42  ? 381 TRP C CE2   1 
ATOM   11125 C CE3   . TRP C 1 381 ? -31.020 1.303   -87.060  1.00 61.20  ? 381 TRP C CE3   1 
ATOM   11126 C CZ2   . TRP C 1 381 ? -28.955 1.780   -88.949  1.00 58.48  ? 381 TRP C CZ2   1 
ATOM   11127 C CZ3   . TRP C 1 381 ? -31.036 2.412   -87.872  1.00 66.04  ? 381 TRP C CZ3   1 
ATOM   11128 C CH2   . TRP C 1 381 ? -30.022 2.638   -88.808  1.00 66.40  ? 381 TRP C CH2   1 
ATOM   11129 N N     . ASP C 1 382 ? -31.164 -3.946  -87.685  1.00 86.77  ? 382 ASP C N     1 
ATOM   11130 C CA    . ASP C 1 382 ? -30.668 -5.210  -88.222  1.00 91.00  ? 382 ASP C CA    1 
ATOM   11131 C C     . ASP C 1 382 ? -31.406 -6.417  -87.633  1.00 86.71  ? 382 ASP C C     1 
ATOM   11132 O O     . ASP C 1 382 ? -30.791 -7.457  -87.389  1.00 82.17  ? 382 ASP C O     1 
ATOM   11133 C CB    . ASP C 1 382 ? -29.151 -5.362  -88.035  1.00 88.68  ? 382 ASP C CB    1 
ATOM   11134 C CG    . ASP C 1 382 ? -28.440 -6.066  -89.188  1.00 98.53  ? 382 ASP C CG    1 
ATOM   11135 O OD1   . ASP C 1 382 ? -29.083 -6.293  -90.255  1.00 92.80  ? 382 ASP C OD1   1 
ATOM   11136 O OD2   . ASP C 1 382 ? -27.236 -6.359  -89.032  1.00 90.53  ? 382 ASP C OD2   1 
ATOM   11137 N N     . GLY C 1 383 ? -32.725 -6.287  -87.434  1.00 83.23  ? 383 GLY C N     1 
ATOM   11138 C CA    . GLY C 1 383 ? -33.601 -7.442  -87.294  1.00 92.44  ? 383 GLY C CA    1 
ATOM   11139 C C     . GLY C 1 383 ? -33.664 -8.044  -85.886  1.00 101.01 ? 383 GLY C C     1 
ATOM   11140 O O     . GLY C 1 383 ? -34.234 -9.125  -85.728  1.00 87.49  ? 383 GLY C O     1 
ATOM   11141 N N     . GLY C 1 384 ? -33.079 -7.367  -84.879  1.00 106.32 ? 384 GLY C N     1 
ATOM   11142 C CA    . GLY C 1 384 ? -33.301 -7.701  -83.476  1.00 99.26  ? 384 GLY C CA    1 
ATOM   11143 C C     . GLY C 1 384 ? -32.312 -8.724  -82.909  1.00 98.25  ? 384 GLY C C     1 
ATOM   11144 O O     . GLY C 1 384 ? -31.997 -9.733  -83.537  1.00 105.62 ? 384 GLY C O     1 
ATOM   11145 N N     . GLY C 1 385 ? -31.854 -8.471  -81.680  1.00 90.59  ? 385 GLY C N     1 
ATOM   11146 C CA    . GLY C 1 385 ? -31.117 -9.460  -80.909  1.00 88.10  ? 385 GLY C CA    1 
ATOM   11147 C C     . GLY C 1 385 ? -30.692 -8.889  -79.558  1.00 90.13  ? 385 GLY C C     1 
ATOM   11148 O O     . GLY C 1 385 ? -31.379 -8.025  -79.014  1.00 80.31  ? 385 GLY C O     1 
ATOM   11149 N N     . GLY C 1 386 ? -29.542 -9.355  -79.045  1.00 87.36  ? 386 GLY C N     1 
ATOM   11150 C CA    . GLY C 1 386 ? -28.988 -8.865  -77.788  1.00 83.63  ? 386 GLY C CA    1 
ATOM   11151 C C     . GLY C 1 386 ? -28.032 -7.678  -77.951  1.00 81.45  ? 386 GLY C C     1 
ATOM   11152 O O     . GLY C 1 386 ? -27.731 -7.245  -79.069  1.00 70.33  ? 386 GLY C O     1 
ATOM   11153 N N     . HIS C 1 387 ? -27.551 -7.149  -76.813  1.00 72.57  ? 387 HIS C N     1 
ATOM   11154 C CA    . HIS C 1 387 ? -26.498 -6.146  -76.845  1.00 73.95  ? 387 HIS C CA    1 
ATOM   11155 C C     . HIS C 1 387 ? -25.373 -6.515  -75.881  1.00 71.22  ? 387 HIS C C     1 
ATOM   11156 O O     . HIS C 1 387 ? -25.513 -7.398  -75.037  1.00 60.54  ? 387 HIS C O     1 
ATOM   11157 C CB    . HIS C 1 387 ? -27.041 -4.713  -76.689  1.00 85.91  ? 387 HIS C CB    1 
ATOM   11158 C CG    . HIS C 1 387 ? -27.504 -4.254  -75.336  1.00 94.85  ? 387 HIS C CG    1 
ATOM   11159 N ND1   . HIS C 1 387 ? -26.815 -3.285  -74.637  1.00 95.42  ? 387 HIS C ND1   1 
ATOM   11160 C CD2   . HIS C 1 387 ? -28.597 -4.558  -74.602  1.00 108.51 ? 387 HIS C CD2   1 
ATOM   11161 C CE1   . HIS C 1 387 ? -27.441 -3.021  -73.496  1.00 115.02 ? 387 HIS C CE1   1 
ATOM   11162 N NE2   . HIS C 1 387 ? -28.584 -3.797  -73.418  1.00 119.80 ? 387 HIS C NE2   1 
ATOM   11163 N N     . VAL C 1 388 ? -24.224 -5.863  -76.097  1.00 72.53  ? 388 VAL C N     1 
ATOM   11164 C CA    . VAL C 1 388 ? -23.149 -5.801  -75.123  1.00 67.67  ? 388 VAL C CA    1 
ATOM   11165 C C     . VAL C 1 388 ? -22.469 -4.443  -75.284  1.00 63.35  ? 388 VAL C C     1 
ATOM   11166 O O     . VAL C 1 388 ? -22.453 -3.881  -76.379  1.00 61.63  ? 388 VAL C O     1 
ATOM   11167 C CB    . VAL C 1 388 ? -22.157 -6.974  -75.261  1.00 75.44  ? 388 VAL C CB    1 
ATOM   11168 C CG1   . VAL C 1 388 ? -21.042 -6.676  -76.250  1.00 79.55  ? 388 VAL C CG1   1 
ATOM   11169 C CG2   . VAL C 1 388 ? -21.563 -7.363  -73.918  1.00 81.88  ? 388 VAL C CG2   1 
ATOM   11170 N N     . GLY C 1 389 ? -21.953 -3.926  -74.159  1.00 65.50  ? 389 GLY C N     1 
ATOM   11171 C CA    . GLY C 1 389 ? -21.351 -2.607  -74.067  1.00 55.36  ? 389 GLY C CA    1 
ATOM   11172 C C     . GLY C 1 389 ? -19.865 -2.714  -73.728  1.00 53.14  ? 389 GLY C C     1 
ATOM   11173 O O     . GLY C 1 389 ? -19.403 -3.724  -73.194  1.00 45.12  ? 389 GLY C O     1 
ATOM   11174 N N     . PHE C 1 390 ? -19.116 -1.670  -74.092  1.00 58.47  ? 390 PHE C N     1 
ATOM   11175 C CA    . PHE C 1 390 ? -17.741 -1.493  -73.652  1.00 60.40  ? 390 PHE C CA    1 
ATOM   11176 C C     . PHE C 1 390 ? -17.598 -0.006  -73.346  1.00 63.74  ? 390 PHE C C     1 
ATOM   11177 O O     . PHE C 1 390 ? -17.881 0.815   -74.229  1.00 66.59  ? 390 PHE C O     1 
ATOM   11178 C CB    . PHE C 1 390 ? -16.767 -2.027  -74.709  1.00 60.58  ? 390 PHE C CB    1 
ATOM   11179 C CG    . PHE C 1 390 ? -15.308 -1.971  -74.334  1.00 59.47  ? 390 PHE C CG    1 
ATOM   11180 C CD1   . PHE C 1 390 ? -14.823 -2.701  -73.262  1.00 63.15  ? 390 PHE C CD1   1 
ATOM   11181 C CD2   . PHE C 1 390 ? -14.414 -1.194  -75.059  1.00 55.97  ? 390 PHE C CD2   1 
ATOM   11182 C CE1   . PHE C 1 390 ? -13.485 -2.622  -72.898  1.00 61.27  ? 390 PHE C CE1   1 
ATOM   11183 C CE2   . PHE C 1 390 ? -13.076 -1.124  -74.708  1.00 50.14  ? 390 PHE C CE2   1 
ATOM   11184 C CZ    . PHE C 1 390 ? -12.608 -1.856  -73.641  1.00 60.31  ? 390 PHE C CZ    1 
ATOM   11185 N N     . SER C 1 391 ? -17.218 0.314   -72.089  1.00 59.10  ? 391 SER C N     1 
ATOM   11186 C CA    . SER C 1 391 ? -17.254 1.681   -71.564  1.00 59.12  ? 391 SER C CA    1 
ATOM   11187 C C     . SER C 1 391 ? -15.984 2.047   -70.782  1.00 60.97  ? 391 SER C C     1 
ATOM   11188 O O     . SER C 1 391 ? -16.043 2.501   -69.640  1.00 60.94  ? 391 SER C O     1 
ATOM   11189 C CB    . SER C 1 391 ? -18.464 1.833   -70.704  1.00 50.36  ? 391 SER C CB    1 
ATOM   11190 O OG    . SER C 1 391 ? -18.602 0.662   -69.917  1.00 56.55  ? 391 SER C OG    1 
ATOM   11191 N N     . PRO C 1 392 ? -14.776 1.936   -71.372  1.00 55.76  ? 392 PRO C N     1 
ATOM   11192 C CA    . PRO C 1 392 ? -13.557 2.333   -70.668  1.00 55.16  ? 392 PRO C CA    1 
ATOM   11193 C C     . PRO C 1 392 ? -13.485 3.824   -70.351  1.00 47.23  ? 392 PRO C C     1 
ATOM   11194 O O     . PRO C 1 392 ? -14.337 4.609   -70.753  1.00 52.21  ? 392 PRO C O     1 
ATOM   11195 C CB    . PRO C 1 392 ? -12.443 1.906   -71.634  1.00 52.05  ? 392 PRO C CB    1 
ATOM   11196 C CG    . PRO C 1 392 ? -13.097 1.976   -72.972  1.00 54.89  ? 392 PRO C CG    1 
ATOM   11197 C CD    . PRO C 1 392 ? -14.510 1.482   -72.742  1.00 52.48  ? 392 PRO C CD    1 
ATOM   11198 N N     . VAL C 1 393 ? -12.454 4.186   -69.594  1.00 46.20  ? 393 VAL C N     1 
ATOM   11199 C CA    . VAL C 1 393 ? -12.315 5.522   -69.040  1.00 50.17  ? 393 VAL C CA    1 
ATOM   11200 C C     . VAL C 1 393 ? -11.047 6.155   -69.610  1.00 52.41  ? 393 VAL C C     1 
ATOM   11201 O O     . VAL C 1 393 ? -10.002 5.481   -69.689  1.00 47.95  ? 393 VAL C O     1 
ATOM   11202 C CB    . VAL C 1 393 ? -12.214 5.484   -67.504  1.00 55.03  ? 393 VAL C CB    1 
ATOM   11203 C CG1   . VAL C 1 393 ? -12.184 6.883   -66.914  1.00 53.03  ? 393 VAL C CG1   1 
ATOM   11204 C CG2   . VAL C 1 393 ? -13.327 4.657   -66.891  1.00 63.24  ? 393 VAL C CG2   1 
ATOM   11205 N N     . SER C 1 394 ? -11.156 7.468   -69.877  1.00 44.95  ? 394 SER C N     1 
ATOM   11206 C CA    . SER C 1 394 ? -10.137 8.239   -70.558  1.00 49.23  ? 394 SER C CA    1 
ATOM   11207 C C     . SER C 1 394 ? -10.225 9.692   -70.117  1.00 53.76  ? 394 SER C C     1 
ATOM   11208 O O     . SER C 1 394 ? -11.179 10.135  -69.469  1.00 51.85  ? 394 SER C O     1 
ATOM   11209 C CB    . SER C 1 394 ? -10.276 8.140   -72.070  1.00 54.64  ? 394 SER C CB    1 
ATOM   11210 O OG    . SER C 1 394 ? -11.503 8.703   -72.547  1.00 49.76  ? 394 SER C OG    1 
ATOM   11211 N N     . PRO C 1 395 ? -9.175  10.472  -70.402  1.00 52.85  ? 395 PRO C N     1 
ATOM   11212 C CA    . PRO C 1 395 ? -9.244  11.922  -70.203  1.00 51.72  ? 395 PRO C CA    1 
ATOM   11213 C C     . PRO C 1 395 ? -10.243 12.586  -71.138  1.00 47.88  ? 395 PRO C C     1 
ATOM   11214 O O     . PRO C 1 395 ? -10.445 12.115  -72.249  1.00 50.59  ? 395 PRO C O     1 
ATOM   11215 C CB    . PRO C 1 395 ? -7.797  12.378  -70.486  1.00 48.27  ? 395 PRO C CB    1 
ATOM   11216 C CG    . PRO C 1 395 ? -6.971  11.139  -70.160  1.00 48.98  ? 395 PRO C CG    1 
ATOM   11217 C CD    . PRO C 1 395 ? -7.817  9.981   -70.655  1.00 48.04  ? 395 PRO C CD    1 
ATOM   11218 N N     . ILE C 1 396 ? -10.818 13.705  -70.689  1.00 50.35  ? 396 ILE C N     1 
ATOM   11219 C CA    . ILE C 1 396 ? -11.666 14.534  -71.532  1.00 47.83  ? 396 ILE C CA    1 
ATOM   11220 C C     . ILE C 1 396 ? -10.748 15.375  -72.413  1.00 52.02  ? 396 ILE C C     1 
ATOM   11221 O O     . ILE C 1 396 ? -10.442 16.527  -72.082  1.00 45.40  ? 396 ILE C O     1 
ATOM   11222 C CB    . ILE C 1 396 ? -12.640 15.415  -70.728  1.00 46.89  ? 396 ILE C CB    1 
ATOM   11223 C CG1   . ILE C 1 396 ? -13.422 14.633  -69.671  1.00 47.13  ? 396 ILE C CG1   1 
ATOM   11224 C CG2   . ILE C 1 396 ? -13.582 16.125  -71.671  1.00 45.33  ? 396 ILE C CG2   1 
ATOM   11225 C CD1   . ILE C 1 396 ? -14.043 15.510  -68.619  1.00 49.75  ? 396 ILE C CD1   1 
ATOM   11226 N N     . THR C 1 397 ? -10.362 14.753  -73.542  1.00 53.28  ? 397 THR C N     1 
ATOM   11227 C CA    . THR C 1 397 ? -9.463  15.296  -74.552  1.00 53.32  ? 397 THR C CA    1 
ATOM   11228 C C     . THR C 1 397 ? -10.016 14.961  -75.936  1.00 52.92  ? 397 THR C C     1 
ATOM   11229 O O     . THR C 1 397 ? -10.342 13.798  -76.211  1.00 49.15  ? 397 THR C O     1 
ATOM   11230 C CB    . THR C 1 397 ? -8.081  14.693  -74.288  1.00 53.31  ? 397 THR C CB    1 
ATOM   11231 O OG1   . THR C 1 397 ? -7.533  15.461  -73.228  1.00 52.56  ? 397 THR C OG1   1 
ATOM   11232 C CG2   . THR C 1 397 ? -7.119  14.714  -75.436  1.00 56.07  ? 397 THR C CG2   1 
ATOM   11233 N N     . GLY C 1 398 ? -10.119 15.983  -76.794  1.00 55.40  ? 398 GLY C N     1 
ATOM   11234 C CA    . GLY C 1 398 ? -10.529 15.808  -78.184  1.00 53.59  ? 398 GLY C CA    1 
ATOM   11235 C C     . GLY C 1 398 ? -9.815  14.627  -78.843  1.00 52.37  ? 398 GLY C C     1 
ATOM   11236 O O     . GLY C 1 398 ? -10.431 13.766  -79.468  1.00 52.76  ? 398 GLY C O     1 
ATOM   11237 N N     . LYS C 1 399 ? -8.505  14.597  -78.620  1.00 51.80  ? 399 LYS C N     1 
ATOM   11238 C CA    . LYS C 1 399 ? -7.573  13.628  -79.159  1.00 58.05  ? 399 LYS C CA    1 
ATOM   11239 C C     . LYS C 1 399 ? -7.894  12.222  -78.649  1.00 53.47  ? 399 LYS C C     1 
ATOM   11240 O O     . LYS C 1 399 ? -7.809  11.284  -79.446  1.00 58.31  ? 399 LYS C O     1 
ATOM   11241 C CB    . LYS C 1 399 ? -6.156  14.123  -78.820  1.00 71.04  ? 399 LYS C CB    1 
ATOM   11242 C CG    . LYS C 1 399 ? -4.967  13.348  -79.378  1.00 88.39  ? 399 LYS C CG    1 
ATOM   11243 C CD    . LYS C 1 399 ? -3.650  13.817  -78.752  1.00 100.26 ? 399 LYS C CD    1 
ATOM   11244 C CE    . LYS C 1 399 ? -2.662  12.704  -78.470  1.00 101.81 ? 399 LYS C CE    1 
ATOM   11245 N NZ    . LYS C 1 399 ? -1.647  12.572  -79.538  1.00 104.05 ? 399 LYS C NZ    1 
ATOM   11246 N N     . ASP C 1 400 ? -8.256  12.065  -77.358  1.00 55.32  ? 400 ASP C N     1 
ATOM   11247 C CA    . ASP C 1 400 ? -8.656  10.765  -76.813  1.00 51.99  ? 400 ASP C CA    1 
ATOM   11248 C C     . ASP C 1 400 ? -10.014 10.324  -77.381  1.00 54.09  ? 400 ASP C C     1 
ATOM   11249 O O     . ASP C 1 400 ? -10.226 9.147   -77.700  1.00 47.49  ? 400 ASP C O     1 
ATOM   11250 C CB    . ASP C 1 400 ? -8.766  10.790  -75.292  1.00 49.99  ? 400 ASP C CB    1 
ATOM   11251 C CG    . ASP C 1 400 ? -7.450  10.840  -74.547  1.00 49.32  ? 400 ASP C CG    1 
ATOM   11252 O OD1   . ASP C 1 400 ? -6.685  9.869   -74.650  1.00 49.95  ? 400 ASP C OD1   1 
ATOM   11253 O OD2   . ASP C 1 400 ? -7.217  11.840  -73.838  1.00 49.44  ? 400 ASP C OD2   1 
ATOM   11254 N N     . ALA C 1 401 ? -10.950 11.279  -77.481  1.00 53.10  ? 401 ALA C N     1 
ATOM   11255 C CA    . ALA C 1 401 ? -12.263 11.027  -78.057  1.00 57.78  ? 401 ALA C CA    1 
ATOM   11256 C C     . ALA C 1 401 ? -12.115 10.444  -79.460  1.00 62.82  ? 401 ALA C C     1 
ATOM   11257 O O     . ALA C 1 401 ? -12.566 9.323   -79.722  1.00 55.52  ? 401 ALA C O     1 
ATOM   11258 C CB    . ALA C 1 401 ? -13.056 12.311  -78.101  1.00 59.89  ? 401 ALA C CB    1 
ATOM   11259 N N     . ILE C 1 402 ? -11.477 11.218  -80.357  1.00 59.96  ? 402 ILE C N     1 
ATOM   11260 C CA    . ILE C 1 402 ? -11.420 10.824  -81.754  1.00 61.36  ? 402 ILE C CA    1 
ATOM   11261 C C     . ILE C 1 402 ? -10.548 9.578   -81.908  1.00 57.49  ? 402 ILE C C     1 
ATOM   11262 O O     . ILE C 1 402 ? -10.851 8.718   -82.730  1.00 56.76  ? 402 ILE C O     1 
ATOM   11263 C CB    . ILE C 1 402 ? -10.970 11.965  -82.681  1.00 56.88  ? 402 ILE C CB    1 
ATOM   11264 C CG1   . ILE C 1 402 ? -11.317 11.665  -84.150  1.00 53.52  ? 402 ILE C CG1   1 
ATOM   11265 C CG2   . ILE C 1 402 ? -9.492  12.242  -82.481  1.00 53.76  ? 402 ILE C CG2   1 
ATOM   11266 C CD1   . ILE C 1 402 ? -11.269 12.882  -85.059  1.00 56.83  ? 402 ILE C CD1   1 
ATOM   11267 N N     . LYS C 1 403 ? -9.498  9.453   -81.095  1.00 51.87  ? 403 LYS C N     1 
ATOM   11268 C CA    . LYS C 1 403 ? -8.689  8.247   -81.131  1.00 49.71  ? 403 LYS C CA    1 
ATOM   11269 C C     . LYS C 1 403 ? -9.586  7.027   -80.922  1.00 49.52  ? 403 LYS C C     1 
ATOM   11270 O O     . LYS C 1 403 ? -9.448  6.018   -81.616  1.00 56.50  ? 403 LYS C O     1 
ATOM   11271 C CB    . LYS C 1 403 ? -7.552  8.320   -80.104  1.00 51.07  ? 403 LYS C CB    1 
ATOM   11272 C CG    . LYS C 1 403 ? -6.472  7.277   -80.319  1.00 55.87  ? 403 LYS C CG    1 
ATOM   11273 C CD    . LYS C 1 403 ? -5.896  6.664   -79.067  1.00 58.69  ? 403 LYS C CD    1 
ATOM   11274 C CE    . LYS C 1 403 ? -4.568  7.264   -78.678  1.00 62.77  ? 403 LYS C CE    1 
ATOM   11275 N NZ    . LYS C 1 403 ? -4.024  6.516   -77.527  1.00 66.39  ? 403 LYS C NZ    1 
ATOM   11276 N N     . GLN C 1 404 ? -10.519 7.108   -79.972  1.00 51.81  ? 404 GLN C N     1 
ATOM   11277 C CA    . GLN C 1 404 ? -11.305 5.935   -79.601  1.00 59.19  ? 404 GLN C CA    1 
ATOM   11278 C C     . GLN C 1 404 ? -12.446 5.700   -80.597  1.00 55.47  ? 404 GLN C C     1 
ATOM   11279 O O     . GLN C 1 404 ? -12.755 4.558   -80.916  1.00 63.22  ? 404 GLN C O     1 
ATOM   11280 C CB    . GLN C 1 404 ? -11.819 6.068   -78.165  1.00 58.43  ? 404 GLN C CB    1 
ATOM   11281 C CG    . GLN C 1 404 ? -10.766 5.772   -77.115  1.00 55.00  ? 404 GLN C CG    1 
ATOM   11282 C CD    . GLN C 1 404 ? -11.268 6.093   -75.729  1.00 58.11  ? 404 GLN C CD    1 
ATOM   11283 O OE1   . GLN C 1 404 ? -11.678 5.209   -74.968  1.00 54.80  ? 404 GLN C OE1   1 
ATOM   11284 N NE2   . GLN C 1 404 ? -11.290 7.383   -75.429  1.00 61.00  ? 404 GLN C NE2   1 
ATOM   11285 N N     . TYR C 1 405 ? -13.085 6.771   -81.081  1.00 54.45  ? 405 TYR C N     1 
ATOM   11286 C CA    . TYR C 1 405 ? -13.928 6.689   -82.267  1.00 56.61  ? 405 TYR C CA    1 
ATOM   11287 C C     . TYR C 1 405 ? -13.265 5.834   -83.355  1.00 54.70  ? 405 TYR C C     1 
ATOM   11288 O O     . TYR C 1 405 ? -13.797 4.807   -83.765  1.00 65.62  ? 405 TYR C O     1 
ATOM   11289 C CB    . TYR C 1 405 ? -14.223 8.085   -82.830  1.00 57.37  ? 405 TYR C CB    1 
ATOM   11290 C CG    . TYR C 1 405 ? -14.988 8.053   -84.128  1.00 57.61  ? 405 TYR C CG    1 
ATOM   11291 C CD1   . TYR C 1 405 ? -16.212 7.409   -84.218  1.00 63.97  ? 405 TYR C CD1   1 
ATOM   11292 C CD2   . TYR C 1 405 ? -14.492 8.643   -85.268  1.00 58.15  ? 405 TYR C CD2   1 
ATOM   11293 C CE1   . TYR C 1 405 ? -16.927 7.361   -85.400  1.00 55.25  ? 405 TYR C CE1   1 
ATOM   11294 C CE2   . TYR C 1 405 ? -15.194 8.602   -86.458  1.00 58.08  ? 405 TYR C CE2   1 
ATOM   11295 C CZ    . TYR C 1 405 ? -16.401 7.939   -86.527  1.00 53.91  ? 405 TYR C CZ    1 
ATOM   11296 O OH    . TYR C 1 405 ? -17.093 7.869   -87.699  1.00 69.70  ? 405 TYR C OH    1 
ATOM   11297 N N     . ASN C 1 406 ? -12.092 6.263   -83.820  1.00 48.87  ? 406 ASN C N     1 
ATOM   11298 C CA    . ASN C 1 406 ? -11.396 5.596   -84.901  1.00 48.01  ? 406 ASN C CA    1 
ATOM   11299 C C     . ASN C 1 406 ? -11.016 4.170   -84.527  1.00 50.94  ? 406 ASN C C     1 
ATOM   11300 O O     . ASN C 1 406 ? -11.172 3.271   -85.350  1.00 50.12  ? 406 ASN C O     1 
ATOM   11301 C CB    . ASN C 1 406 ? -10.162 6.372   -85.338  1.00 50.12  ? 406 ASN C CB    1 
ATOM   11302 C CG    . ASN C 1 406 ? -10.517 7.426   -86.357  1.00 55.21  ? 406 ASN C CG    1 
ATOM   11303 O OD1   . ASN C 1 406 ? -10.889 7.100   -87.487  1.00 70.77  ? 406 ASN C OD1   1 
ATOM   11304 N ND2   . ASN C 1 406 ? -10.413 8.679   -85.965  1.00 53.70  ? 406 ASN C ND2   1 
ATOM   11305 N N     . MET C 1 407 ? -10.484 3.967   -83.322  1.00 51.31  ? 407 MET C N     1 
ATOM   11306 C CA    . MET C 1 407 ? -10.099 2.627   -82.897  1.00 58.27  ? 407 MET C CA    1 
ATOM   11307 C C     . MET C 1 407 ? -11.282 1.687   -83.084  1.00 54.22  ? 407 MET C C     1 
ATOM   11308 O O     . MET C 1 407 ? -11.133 0.619   -83.690  1.00 50.23  ? 407 MET C O     1 
ATOM   11309 C CB    . MET C 1 407 ? -9.694  2.588   -81.418  1.00 66.02  ? 407 MET C CB    1 
ATOM   11310 C CG    . MET C 1 407 ? -8.215  2.850   -81.173  1.00 70.89  ? 407 MET C CG    1 
ATOM   11311 S SD    . MET C 1 407 ? -7.813  3.079   -79.407  1.00 68.04  ? 407 MET C SD    1 
ATOM   11312 C CE    . MET C 1 407 ? -7.890  1.388   -78.809  1.00 57.61  ? 407 MET C CE    1 
ATOM   11313 N N     . VAL C 1 408 ? -12.453 2.110   -82.571  1.00 49.90  ? 408 VAL C N     1 
ATOM   11314 C CA    . VAL C 1 408 ? -13.562 1.189   -82.382  1.00 54.85  ? 408 VAL C CA    1 
ATOM   11315 C C     . VAL C 1 408 ? -14.366 1.055   -83.673  1.00 52.37  ? 408 VAL C C     1 
ATOM   11316 O O     . VAL C 1 408 ? -14.609 -0.057  -84.109  1.00 54.50  ? 408 VAL C O     1 
ATOM   11317 C CB    . VAL C 1 408 ? -14.468 1.576   -81.200  1.00 60.13  ? 408 VAL C CB    1 
ATOM   11318 C CG1   . VAL C 1 408 ? -15.665 0.638   -81.104  1.00 62.18  ? 408 VAL C CG1   1 
ATOM   11319 C CG2   . VAL C 1 408 ? -13.713 1.583   -79.876  1.00 59.58  ? 408 VAL C CG2   1 
ATOM   11320 N N     . SER C 1 409 ? -14.767 2.167   -84.295  1.00 56.67  ? 409 SER C N     1 
ATOM   11321 C CA    . SER C 1 409 ? -15.578 2.059   -85.497  1.00 60.34  ? 409 SER C CA    1 
ATOM   11322 C C     . SER C 1 409 ? -14.861 1.151   -86.488  1.00 55.81  ? 409 SER C C     1 
ATOM   11323 O O     . SER C 1 409 ? -15.477 0.227   -86.981  1.00 71.09  ? 409 SER C O     1 
ATOM   11324 C CB    . SER C 1 409 ? -15.950 3.387   -86.105  1.00 54.63  ? 409 SER C CB    1 
ATOM   11325 O OG    . SER C 1 409 ? -14.791 4.151   -86.368  1.00 55.79  ? 409 SER C OG    1 
ATOM   11326 N N     . SER C 1 410 ? -13.556 1.341   -86.712  1.00 62.36  ? 410 SER C N     1 
ATOM   11327 C CA    . SER C 1 410 ? -12.829 0.528   -87.690  1.00 60.37  ? 410 SER C CA    1 
ATOM   11328 C C     . SER C 1 410 ? -12.933 -0.963  -87.372  1.00 59.85  ? 410 SER C C     1 
ATOM   11329 O O     . SER C 1 410 ? -13.117 -1.774  -88.277  1.00 62.07  ? 410 SER C O     1 
ATOM   11330 C CB    . SER C 1 410 ? -11.394 0.927   -87.812  1.00 60.40  ? 410 SER C CB    1 
ATOM   11331 O OG    . SER C 1 410 ? -10.670 0.522   -86.659  1.00 67.70  ? 410 SER C OG    1 
ATOM   11332 N N     . ARG C 1 411 ? -12.820 -1.318  -86.090  1.00 55.27  ? 411 ARG C N     1 
ATOM   11333 C CA    . ARG C 1 411 ? -12.791 -2.715  -85.703  1.00 60.16  ? 411 ARG C CA    1 
ATOM   11334 C C     . ARG C 1 411 ? -14.183 -3.324  -85.769  1.00 63.49  ? 411 ARG C C     1 
ATOM   11335 O O     . ARG C 1 411 ? -14.326 -4.486  -86.169  1.00 61.28  ? 411 ARG C O     1 
ATOM   11336 C CB    . ARG C 1 411 ? -12.267 -2.873  -84.276  1.00 61.48  ? 411 ARG C CB    1 
ATOM   11337 C CG    . ARG C 1 411 ? -10.772 -2.651  -84.172  1.00 58.47  ? 411 ARG C CG    1 
ATOM   11338 C CD    . ARG C 1 411 ? -10.123 -3.928  -84.616  1.00 61.64  ? 411 ARG C CD    1 
ATOM   11339 N NE    . ARG C 1 411 ? -8.691  -3.839  -84.447  1.00 57.51  ? 411 ARG C NE    1 
ATOM   11340 C CZ    . ARG C 1 411 ? -7.820  -4.231  -85.352  1.00 60.22  ? 411 ARG C CZ    1 
ATOM   11341 N NH1   . ARG C 1 411 ? -8.247  -4.768  -86.482  1.00 62.69  ? 411 ARG C NH1   1 
ATOM   11342 N NH2   . ARG C 1 411 ? -6.526  -4.064  -85.131  1.00 65.19  ? 411 ARG C NH2   1 
ATOM   11343 N N     . VAL C 1 412 ? -15.174 -2.554  -85.304  1.00 59.08  ? 412 VAL C N     1 
ATOM   11344 C CA    . VAL C 1 412 ? -16.556 -3.005  -85.279  1.00 63.98  ? 412 VAL C CA    1 
ATOM   11345 C C     . VAL C 1 412 ? -17.025 -3.279  -86.717  1.00 58.78  ? 412 VAL C C     1 
ATOM   11346 O O     . VAL C 1 412 ? -17.503 -4.373  -87.014  1.00 46.56  ? 412 VAL C O     1 
ATOM   11347 C CB    . VAL C 1 412 ? -17.452 -2.000  -84.523  1.00 72.64  ? 412 VAL C CB    1 
ATOM   11348 C CG1   . VAL C 1 412 ? -18.928 -2.326  -84.659  1.00 88.93  ? 412 VAL C CG1   1 
ATOM   11349 C CG2   . VAL C 1 412 ? -17.096 -1.930  -83.047  1.00 80.17  ? 412 VAL C CG2   1 
ATOM   11350 N N     . ARG C 1 413 ? -16.844 -2.300  -87.617  1.00 53.68  ? 413 ARG C N     1 
ATOM   11351 C CA    . ARG C 1 413 ? -17.273 -2.426  -89.000  1.00 52.10  ? 413 ARG C CA    1 
ATOM   11352 C C     . ARG C 1 413 ? -16.496 -3.555  -89.667  1.00 51.96  ? 413 ARG C C     1 
ATOM   11353 O O     . ARG C 1 413 ? -17.089 -4.347  -90.379  1.00 54.16  ? 413 ARG C O     1 
ATOM   11354 C CB    . ARG C 1 413 ? -17.166 -1.082  -89.723  1.00 50.54  ? 413 ARG C CB    1 
ATOM   11355 C CG    . ARG C 1 413 ? -18.191 -0.055  -89.249  1.00 52.74  ? 413 ARG C CG    1 
ATOM   11356 C CD    . ARG C 1 413 ? -17.801 1.369   -89.608  1.00 58.99  ? 413 ARG C CD    1 
ATOM   11357 N NE    . ARG C 1 413 ? -17.720 1.560   -91.055  1.00 71.98  ? 413 ARG C NE    1 
ATOM   11358 C CZ    . ARG C 1 413 ? -18.750 1.650   -91.900  1.00 69.75  ? 413 ARG C CZ    1 
ATOM   11359 N NH1   . ARG C 1 413 ? -19.994 1.806   -91.461  1.00 73.22  ? 413 ARG C NH1   1 
ATOM   11360 N NH2   . ARG C 1 413 ? -18.511 1.633   -93.200  1.00 65.80  ? 413 ARG C NH2   1 
ATOM   11361 N N     . GLU C 1 414 ? -15.199 -3.678  -89.358  1.00 57.03  ? 414 GLU C N     1 
ATOM   11362 C CA    . GLU C 1 414 ? -14.388 -4.801  -89.811  1.00 57.65  ? 414 GLU C CA    1 
ATOM   11363 C C     . GLU C 1 414 ? -15.120 -6.121  -89.553  1.00 55.52  ? 414 GLU C C     1 
ATOM   11364 O O     . GLU C 1 414 ? -15.131 -6.963  -90.443  1.00 64.31  ? 414 GLU C O     1 
ATOM   11365 C CB    . GLU C 1 414 ? -12.983 -4.760  -89.191  1.00 58.82  ? 414 GLU C CB    1 
ATOM   11366 C CG    . GLU C 1 414 ? -12.158 -6.029  -89.394  1.00 65.04  ? 414 GLU C CG    1 
ATOM   11367 C CD    . GLU C 1 414 ? -10.790 -6.115  -88.717  1.00 70.43  ? 414 GLU C CD    1 
ATOM   11368 O OE1   . GLU C 1 414 ? -10.365 -5.152  -88.043  1.00 68.98  ? 414 GLU C OE1   1 
ATOM   11369 O OE2   . GLU C 1 414 ? -10.148 -7.165  -88.849  1.00 70.22  ? 414 GLU C OE2   1 
ATOM   11370 N N     . TYR C 1 415 ? -15.759 -6.277  -88.383  1.00 61.74  ? 415 TYR C N     1 
ATOM   11371 C CA    . TYR C 1 415 ? -16.391 -7.537  -87.976  1.00 68.09  ? 415 TYR C CA    1 
ATOM   11372 C C     . TYR C 1 415 ? -17.886 -7.598  -88.329  1.00 67.26  ? 415 TYR C C     1 
ATOM   11373 O O     . TYR C 1 415 ? -18.608 -8.462  -87.823  1.00 58.94  ? 415 TYR C O     1 
ATOM   11374 C CB    . TYR C 1 415 ? -16.195 -7.807  -86.475  1.00 57.50  ? 415 TYR C CB    1 
ATOM   11375 C CG    . TYR C 1 415 ? -14.868 -8.439  -86.144  1.00 56.74  ? 415 TYR C CG    1 
ATOM   11376 C CD1   . TYR C 1 415 ? -13.705 -7.682  -86.176  1.00 58.67  ? 415 TYR C CD1   1 
ATOM   11377 C CD2   . TYR C 1 415 ? -14.755 -9.796  -85.862  1.00 50.45  ? 415 TYR C CD2   1 
ATOM   11378 C CE1   . TYR C 1 415 ? -12.467 -8.251  -85.911  1.00 59.92  ? 415 TYR C CE1   1 
ATOM   11379 C CE2   . TYR C 1 415 ? -13.523 -10.377 -85.594  1.00 49.76  ? 415 TYR C CE2   1 
ATOM   11380 C CZ    . TYR C 1 415 ? -12.375 -9.602  -85.624  1.00 57.70  ? 415 TYR C CZ    1 
ATOM   11381 O OH    . TYR C 1 415 ? -11.122 -10.104 -85.359  1.00 60.92  ? 415 TYR C OH    1 
ATOM   11382 N N     . GLY C 1 416 ? -18.352 -6.687  -89.192  1.00 62.36  ? 416 GLY C N     1 
ATOM   11383 C CA    . GLY C 1 416 ? -19.672 -6.799  -89.795  1.00 71.06  ? 416 GLY C CA    1 
ATOM   11384 C C     . GLY C 1 416 ? -20.814 -6.390  -88.866  1.00 70.50  ? 416 GLY C C     1 
ATOM   11385 O O     . GLY C 1 416 ? -21.897 -6.972  -88.927  1.00 75.93  ? 416 GLY C O     1 
ATOM   11386 N N     . PHE C 1 417 ? -20.547 -5.388  -88.019  1.00 64.21  ? 417 PHE C N     1 
ATOM   11387 C CA    . PHE C 1 417 ? -21.559 -4.734  -87.212  1.00 58.36  ? 417 PHE C CA    1 
ATOM   11388 C C     . PHE C 1 417 ? -21.545 -3.232  -87.500  1.00 56.21  ? 417 PHE C C     1 
ATOM   11389 O O     . PHE C 1 417 ? -20.528 -2.691  -87.925  1.00 56.89  ? 417 PHE C O     1 
ATOM   11390 C CB    . PHE C 1 417 ? -21.305 -4.969  -85.730  1.00 50.20  ? 417 PHE C CB    1 
ATOM   11391 C CG    . PHE C 1 417 ? -21.169 -6.395  -85.285  1.00 48.27  ? 417 PHE C CG    1 
ATOM   11392 C CD1   . PHE C 1 417 ? -22.288 -7.168  -85.030  1.00 58.75  ? 417 PHE C CD1   1 
ATOM   11393 C CD2   . PHE C 1 417 ? -19.925 -6.931  -85.001  1.00 52.03  ? 417 PHE C CD2   1 
ATOM   11394 C CE1   . PHE C 1 417 ? -22.170 -8.476  -84.575  1.00 52.30  ? 417 PHE C CE1   1 
ATOM   11395 C CE2   . PHE C 1 417 ? -19.800 -8.232  -84.529  1.00 54.74  ? 417 PHE C CE2   1 
ATOM   11396 C CZ    . PHE C 1 417 ? -20.926 -9.003  -84.322  1.00 57.13  ? 417 PHE C CZ    1 
ATOM   11397 N N     . ASP C 1 418 ? -22.674 -2.557  -87.259  1.00 56.39  ? 418 ASP C N     1 
ATOM   11398 C CA    . ASP C 1 418 ? -22.703 -1.105  -87.355  1.00 66.55  ? 418 ASP C CA    1 
ATOM   11399 C C     . ASP C 1 418 ? -22.092 -0.507  -86.082  1.00 68.41  ? 418 ASP C C     1 
ATOM   11400 O O     . ASP C 1 418 ? -22.236 -1.061  -84.984  1.00 63.90  ? 418 ASP C O     1 
ATOM   11401 C CB    . ASP C 1 418 ? -24.111 -0.552  -87.610  1.00 61.63  ? 418 ASP C CB    1 
ATOM   11402 C CG    . ASP C 1 418 ? -24.517 -0.450  -89.074  1.00 61.48  ? 418 ASP C CG    1 
ATOM   11403 O OD1   . ASP C 1 418 ? -24.000 0.442   -89.779  1.00 57.50  ? 418 ASP C OD1   1 
ATOM   11404 O OD2   . ASP C 1 418 ? -25.397 -1.232  -89.484  1.00 66.90  ? 418 ASP C OD2   1 
ATOM   11405 N N     . TYR C 1 419 ? -21.410 0.636   -86.266  1.00 58.05  ? 419 TYR C N     1 
ATOM   11406 C CA    . TYR C 1 419 ? -20.838 1.381   -85.167  1.00 56.70  ? 419 TYR C CA    1 
ATOM   11407 C C     . TYR C 1 419 ? -21.897 2.240   -84.480  1.00 64.17  ? 419 TYR C C     1 
ATOM   11408 O O     . TYR C 1 419 ? -22.412 3.215   -85.049  1.00 57.58  ? 419 TYR C O     1 
ATOM   11409 C CB    . TYR C 1 419 ? -19.748 2.346   -85.613  1.00 55.11  ? 419 TYR C CB    1 
ATOM   11410 C CG    . TYR C 1 419 ? -19.355 3.298   -84.513  1.00 53.99  ? 419 TYR C CG    1 
ATOM   11411 C CD1   . TYR C 1 419 ? -18.807 2.822   -83.339  1.00 51.12  ? 419 TYR C CD1   1 
ATOM   11412 C CD2   . TYR C 1 419 ? -19.595 4.659   -84.614  1.00 60.43  ? 419 TYR C CD2   1 
ATOM   11413 C CE1   . TYR C 1 419 ? -18.445 3.675   -82.315  1.00 55.01  ? 419 TYR C CE1   1 
ATOM   11414 C CE2   . TYR C 1 419 ? -19.250 5.526   -83.593  1.00 67.27  ? 419 TYR C CE2   1 
ATOM   11415 C CZ    . TYR C 1 419 ? -18.657 5.032   -82.444  1.00 60.43  ? 419 TYR C CZ    1 
ATOM   11416 O OH    . TYR C 1 419 ? -18.295 5.872   -81.424  1.00 57.14  ? 419 TYR C OH    1 
ATOM   11417 N N     . MET C 1 420 ? -22.154 1.864   -83.222  1.00 63.51  ? 420 MET C N     1 
ATOM   11418 C CA    . MET C 1 420 ? -23.069 2.558   -82.340  1.00 58.90  ? 420 MET C CA    1 
ATOM   11419 C C     . MET C 1 420 ? -22.242 3.062   -81.165  1.00 59.28  ? 420 MET C C     1 
ATOM   11420 O O     . MET C 1 420 ? -21.665 2.271   -80.410  1.00 57.71  ? 420 MET C O     1 
ATOM   11421 C CB    . MET C 1 420 ? -24.171 1.601   -81.869  1.00 54.22  ? 420 MET C CB    1 
ATOM   11422 C CG    . MET C 1 420 ? -25.000 1.065   -83.023  1.00 55.16  ? 420 MET C CG    1 
ATOM   11423 S SD    . MET C 1 420 ? -26.511 0.261   -82.475  1.00 72.32  ? 420 MET C SD    1 
ATOM   11424 C CE    . MET C 1 420 ? -27.077 -0.527  -83.983  1.00 80.99  ? 420 MET C CE    1 
ATOM   11425 N N     . GLY C 1 421 ? -22.151 4.388   -81.058  1.00 61.57  ? 421 GLY C N     1 
ATOM   11426 C CA    . GLY C 1 421 ? -21.228 5.004   -80.125  1.00 61.55  ? 421 GLY C CA    1 
ATOM   11427 C C     . GLY C 1 421 ? -21.800 6.247   -79.463  1.00 59.79  ? 421 GLY C C     1 
ATOM   11428 O O     . GLY C 1 421 ? -22.833 6.765   -79.870  1.00 63.97  ? 421 GLY C O     1 
ATOM   11429 N N     . LEU C 1 422 ? -21.020 6.751   -78.512  1.00 68.77  ? 422 LEU C N     1 
ATOM   11430 C CA    . LEU C 1 422 ? -21.481 7.573   -77.409  1.00 73.55  ? 422 LEU C CA    1 
ATOM   11431 C C     . LEU C 1 422 ? -20.255 7.986   -76.588  1.00 66.41  ? 422 LEU C C     1 
ATOM   11432 O O     . LEU C 1 422 ? -19.610 7.154   -75.954  1.00 65.75  ? 422 LEU C O     1 
ATOM   11433 C CB    . LEU C 1 422 ? -22.438 6.696   -76.592  1.00 79.25  ? 422 LEU C CB    1 
ATOM   11434 C CG    . LEU C 1 422 ? -23.297 7.384   -75.541  1.00 77.88  ? 422 LEU C CG    1 
ATOM   11435 C CD1   . LEU C 1 422 ? -24.215 6.371   -74.879  1.00 79.56  ? 422 LEU C CD1   1 
ATOM   11436 C CD2   . LEU C 1 422 ? -22.448 8.077   -74.502  1.00 82.64  ? 422 LEU C CD2   1 
ATOM   11437 N N     . LEU C 1 423 ? -19.911 9.268   -76.632  1.00 58.96  ? 423 LEU C N     1 
ATOM   11438 C CA    . LEU C 1 423 ? -19.022 9.844   -75.642  1.00 57.28  ? 423 LEU C CA    1 
ATOM   11439 C C     . LEU C 1 423 ? -19.867 10.380  -74.492  1.00 56.69  ? 423 LEU C C     1 
ATOM   11440 O O     . LEU C 1 423 ? -20.723 11.234  -74.719  1.00 63.02  ? 423 LEU C O     1 
ATOM   11441 C CB    . LEU C 1 423 ? -18.189 10.947  -76.297  1.00 56.29  ? 423 LEU C CB    1 
ATOM   11442 C CG    . LEU C 1 423 ? -17.249 10.476  -77.409  1.00 69.45  ? 423 LEU C CG    1 
ATOM   11443 C CD1   . LEU C 1 423 ? -16.108 11.445  -77.589  1.00 83.08  ? 423 LEU C CD1   1 
ATOM   11444 C CD2   . LEU C 1 423 ? -16.671 9.097   -77.145  1.00 77.67  ? 423 LEU C CD2   1 
ATOM   11445 N N     . ALA C 1 424 ? -19.654 9.825   -73.285  1.00 55.79  ? 424 ALA C N     1 
ATOM   11446 C CA    . ALA C 1 424 ? -20.334 10.248  -72.059  1.00 54.63  ? 424 ALA C CA    1 
ATOM   11447 C C     . ALA C 1 424 ? -19.312 10.826  -71.082  1.00 57.49  ? 424 ALA C C     1 
ATOM   11448 O O     . ALA C 1 424 ? -18.228 10.258  -70.890  1.00 51.21  ? 424 ALA C O     1 
ATOM   11449 C CB    . ALA C 1 424 ? -21.074 9.096   -71.421  1.00 50.27  ? 424 ALA C CB    1 
ATOM   11450 N N     . ILE C 1 425 ? -19.651 11.984  -70.500  1.00 61.42  ? 425 ILE C N     1 
ATOM   11451 C CA    . ILE C 1 425 ? -18.796 12.585  -69.493  1.00 61.97  ? 425 ILE C CA    1 
ATOM   11452 C C     . ILE C 1 425 ? -19.530 12.650  -68.160  1.00 61.21  ? 425 ILE C C     1 
ATOM   11453 O O     . ILE C 1 425 ? -20.669 13.112  -68.090  1.00 66.14  ? 425 ILE C O     1 
ATOM   11454 C CB    . ILE C 1 425 ? -18.292 13.968  -69.928  1.00 64.25  ? 425 ILE C CB    1 
ATOM   11455 C CG1   . ILE C 1 425 ? -17.646 13.907  -71.312  1.00 69.67  ? 425 ILE C CG1   1 
ATOM   11456 C CG2   . ILE C 1 425 ? -17.333 14.508  -68.877  1.00 67.06  ? 425 ILE C CG2   1 
ATOM   11457 C CD1   . ILE C 1 425 ? -17.295 15.251  -71.900  1.00 70.29  ? 425 ILE C CD1   1 
ATOM   11458 N N     . GLY C 1 426 ? -18.829 12.202  -67.114  1.00 60.81  ? 426 GLY C N     1 
ATOM   11459 C CA    . GLY C 1 426 ? -19.317 12.248  -65.744  1.00 65.65  ? 426 GLY C CA    1 
ATOM   11460 C C     . GLY C 1 426 ? -19.019 13.603  -65.118  1.00 65.15  ? 426 GLY C C     1 
ATOM   11461 O O     . GLY C 1 426 ? -19.767 14.548  -65.345  1.00 84.27  ? 426 GLY C O     1 
ATOM   11462 N N     . TRP C 1 427 ? -17.896 13.706  -64.395  1.00 54.16  ? 427 TRP C N     1 
ATOM   11463 C CA    . TRP C 1 427 ? -17.430 15.000  -63.912  1.00 51.20  ? 427 TRP C CA    1 
ATOM   11464 C C     . TRP C 1 427 ? -16.092 15.346  -64.569  1.00 47.46  ? 427 TRP C C     1 
ATOM   11465 O O     . TRP C 1 427 ? -16.061 16.268  -65.382  1.00 52.28  ? 427 TRP C O     1 
ATOM   11466 C CB    . TRP C 1 427 ? -17.372 15.023  -62.378  1.00 46.24  ? 427 TRP C CB    1 
ATOM   11467 C CG    . TRP C 1 427 ? -17.296 16.391  -61.782  1.00 45.91  ? 427 TRP C CG    1 
ATOM   11468 C CD1   . TRP C 1 427 ? -17.301 17.592  -62.439  1.00 48.15  ? 427 TRP C CD1   1 
ATOM   11469 C CD2   . TRP C 1 427 ? -17.184 16.704  -60.384  1.00 43.61  ? 427 TRP C CD2   1 
ATOM   11470 N NE1   . TRP C 1 427 ? -17.199 18.624  -61.543  1.00 45.66  ? 427 TRP C NE1   1 
ATOM   11471 C CE2   . TRP C 1 427 ? -17.123 18.111  -60.277  1.00 41.55  ? 427 TRP C CE2   1 
ATOM   11472 C CE3   . TRP C 1 427 ? -17.150 15.935  -59.216  1.00 46.04  ? 427 TRP C CE3   1 
ATOM   11473 C CZ2   . TRP C 1 427 ? -17.046 18.762  -59.051  1.00 45.31  ? 427 TRP C CZ2   1 
ATOM   11474 C CZ3   . TRP C 1 427 ? -17.042 16.580  -58.003  1.00 50.51  ? 427 TRP C CZ3   1 
ATOM   11475 C CH2   . TRP C 1 427 ? -17.007 17.979  -57.923  1.00 44.77  ? 427 TRP C CH2   1 
ATOM   11476 N N     . ARG C 1 428 ? -15.037 14.562  -64.258  1.00 43.48  ? 428 ARG C N     1 
ATOM   11477 C CA    . ARG C 1 428 ? -13.716 14.705  -64.859  1.00 47.30  ? 428 ARG C CA    1 
ATOM   11478 C C     . ARG C 1 428 ? -13.344 13.483  -65.721  1.00 46.86  ? 428 ARG C C     1 
ATOM   11479 O O     . ARG C 1 428 ? -12.165 13.265  -66.036  1.00 50.64  ? 428 ARG C O     1 
ATOM   11480 C CB    . ARG C 1 428 ? -12.676 14.917  -63.742  1.00 44.04  ? 428 ARG C CB    1 
ATOM   11481 C CG    . ARG C 1 428 ? -12.802 16.241  -62.984  1.00 46.75  ? 428 ARG C CG    1 
ATOM   11482 C CD    . ARG C 1 428 ? -12.033 16.218  -61.658  1.00 49.64  ? 428 ARG C CD    1 
ATOM   11483 N NE    . ARG C 1 428 ? -11.762 17.528  -61.060  1.00 46.94  ? 428 ARG C NE    1 
ATOM   11484 C CZ    . ARG C 1 428 ? -12.650 18.293  -60.428  1.00 51.53  ? 428 ARG C CZ    1 
ATOM   11485 N NH1   . ARG C 1 428 ? -13.864 17.843  -60.147  1.00 58.70  ? 428 ARG C NH1   1 
ATOM   11486 N NH2   . ARG C 1 428 ? -12.312 19.517  -60.064  1.00 51.84  ? 428 ARG C NH2   1 
ATOM   11487 N N     . ASP C 1 429 ? -14.340 12.673  -66.094  1.00 42.95  ? 429 ASP C N     1 
ATOM   11488 C CA    . ASP C 1 429 ? -14.103 11.356  -66.678  1.00 50.77  ? 429 ASP C CA    1 
ATOM   11489 C C     . ASP C 1 429 ? -14.839 11.285  -68.029  1.00 54.43  ? 429 ASP C C     1 
ATOM   11490 O O     . ASP C 1 429 ? -16.015 11.650  -68.117  1.00 49.44  ? 429 ASP C O     1 
ATOM   11491 C CB    . ASP C 1 429 ? -14.495 10.223  -65.703  1.00 48.95  ? 429 ASP C CB    1 
ATOM   11492 C CG    . ASP C 1 429 ? -15.967 10.197  -65.269  1.00 50.57  ? 429 ASP C CG    1 
ATOM   11493 O OD1   . ASP C 1 429 ? -16.530 11.285  -64.984  1.00 47.91  ? 429 ASP C OD1   1 
ATOM   11494 O OD2   . ASP C 1 429 ? -16.560 9.101   -65.214  1.00 47.23  ? 429 ASP C OD2   1 
ATOM   11495 N N     . LEU C 1 430 ? -14.124 10.838  -69.078  1.00 53.58  ? 430 LEU C N     1 
ATOM   11496 C CA    . LEU C 1 430 ? -14.716 10.541  -70.374  1.00 55.62  ? 430 LEU C CA    1 
ATOM   11497 C C     . LEU C 1 430 ? -14.844 9.034   -70.544  1.00 55.32  ? 430 LEU C C     1 
ATOM   11498 O O     . LEU C 1 430 ? -13.911 8.297   -70.230  1.00 57.20  ? 430 LEU C O     1 
ATOM   11499 C CB    . LEU C 1 430 ? -13.818 11.108  -71.473  1.00 64.19  ? 430 LEU C CB    1 
ATOM   11500 C CG    . LEU C 1 430 ? -14.379 10.998  -72.893  1.00 66.61  ? 430 LEU C CG    1 
ATOM   11501 C CD1   . LEU C 1 430 ? -15.632 11.851  -73.055  1.00 58.74  ? 430 LEU C CD1   1 
ATOM   11502 C CD2   . LEU C 1 430 ? -13.324 11.388  -73.918  1.00 65.54  ? 430 LEU C CD2   1 
ATOM   11503 N N     . HIS C 1 431 ? -16.014 8.592   -71.020  1.00 59.45  ? 431 HIS C N     1 
ATOM   11504 C CA    . HIS C 1 431 ? -16.217 7.213   -71.448  1.00 58.88  ? 431 HIS C CA    1 
ATOM   11505 C C     . HIS C 1 431 ? -16.612 7.170   -72.927  1.00 58.47  ? 431 HIS C C     1 
ATOM   11506 O O     . HIS C 1 431 ? -17.677 7.635   -73.291  1.00 56.00  ? 431 HIS C O     1 
ATOM   11507 C CB    . HIS C 1 431 ? -17.328 6.552   -70.628  1.00 56.22  ? 431 HIS C CB    1 
ATOM   11508 C CG    . HIS C 1 431 ? -17.084 6.605   -69.159  1.00 58.44  ? 431 HIS C CG    1 
ATOM   11509 N ND1   . HIS C 1 431 ? -16.686 5.512   -68.415  1.00 53.20  ? 431 HIS C ND1   1 
ATOM   11510 C CD2   . HIS C 1 431 ? -17.144 7.638   -68.316  1.00 54.02  ? 431 HIS C CD2   1 
ATOM   11511 C CE1   . HIS C 1 431 ? -16.533 5.889   -67.160  1.00 52.15  ? 431 HIS C CE1   1 
ATOM   11512 N NE2   . HIS C 1 431 ? -16.803 7.177   -67.078  1.00 51.84  ? 431 HIS C NE2   1 
ATOM   11513 N N     . HIS C 1 432 ? -15.752 6.628   -73.794  1.00 60.14  ? 432 HIS C N     1 
ATOM   11514 C CA    . HIS C 1 432 ? -16.194 6.231   -75.116  1.00 55.26  ? 432 HIS C CA    1 
ATOM   11515 C C     . HIS C 1 432 ? -16.939 4.921   -74.964  1.00 53.79  ? 432 HIS C C     1 
ATOM   11516 O O     . HIS C 1 432 ? -16.357 3.946   -74.497  1.00 61.21  ? 432 HIS C O     1 
ATOM   11517 C CB    . HIS C 1 432 ? -15.031 6.018   -76.083  1.00 58.70  ? 432 HIS C CB    1 
ATOM   11518 C CG    . HIS C 1 432 ? -15.542 5.440   -77.356  1.00 58.01  ? 432 HIS C CG    1 
ATOM   11519 N ND1   . HIS C 1 432 ? -15.963 6.242   -78.394  1.00 53.07  ? 432 HIS C ND1   1 
ATOM   11520 C CD2   . HIS C 1 432 ? -15.813 4.172   -77.727  1.00 55.32  ? 432 HIS C CD2   1 
ATOM   11521 C CE1   . HIS C 1 432 ? -16.422 5.471   -79.376  1.00 55.14  ? 432 HIS C CE1   1 
ATOM   11522 N NE2   . HIS C 1 432 ? -16.338 4.211   -79.001  1.00 54.14  ? 432 HIS C NE2   1 
ATOM   11523 N N     . VAL C 1 433 ? -18.222 4.922   -75.326  1.00 59.23  ? 433 VAL C N     1 
ATOM   11524 C CA    . VAL C 1 433 ? -19.083 3.775   -75.065  1.00 62.80  ? 433 VAL C CA    1 
ATOM   11525 C C     . VAL C 1 433 ? -19.520 3.186   -76.399  1.00 57.23  ? 433 VAL C C     1 
ATOM   11526 O O     . VAL C 1 433 ? -20.237 3.832   -77.160  1.00 62.93  ? 433 VAL C O     1 
ATOM   11527 C CB    . VAL C 1 433 ? -20.302 4.157   -74.201  1.00 63.94  ? 433 VAL C CB    1 
ATOM   11528 C CG1   . VAL C 1 433 ? -21.242 2.981   -73.950  1.00 56.01  ? 433 VAL C CG1   1 
ATOM   11529 C CG2   . VAL C 1 433 ? -19.866 4.796   -72.895  1.00 62.27  ? 433 VAL C CG2   1 
ATOM   11530 N N     . THR C 1 434 ? -19.077 1.957   -76.654  1.00 56.77  ? 434 THR C N     1 
ATOM   11531 C CA    . THR C 1 434 ? -19.528 1.160   -77.783  1.00 61.59  ? 434 THR C CA    1 
ATOM   11532 C C     . THR C 1 434 ? -20.735 0.297   -77.402  1.00 67.69  ? 434 THR C C     1 
ATOM   11533 O O     . THR C 1 434 ? -20.640 -0.541  -76.500  1.00 68.05  ? 434 THR C O     1 
ATOM   11534 C CB    . THR C 1 434 ? -18.419 0.197   -78.203  1.00 62.84  ? 434 THR C CB    1 
ATOM   11535 O OG1   . THR C 1 434 ? -17.188 0.898   -78.043  1.00 60.01  ? 434 THR C OG1   1 
ATOM   11536 C CG2   . THR C 1 434 ? -18.607 -0.327  -79.608  1.00 73.89  ? 434 THR C CG2   1 
ATOM   11537 N N     . VAL C 1 435 ? -21.868 0.452   -78.097  1.00 61.69  ? 435 VAL C N     1 
ATOM   11538 C CA    . VAL C 1 435 ? -22.881 -0.580  -77.959  1.00 68.28  ? 435 VAL C CA    1 
ATOM   11539 C C     . VAL C 1 435 ? -22.852 -1.413  -79.236  1.00 56.32  ? 435 VAL C C     1 
ATOM   11540 O O     . VAL C 1 435 ? -22.804 -0.860  -80.313  1.00 52.98  ? 435 VAL C O     1 
ATOM   11541 C CB    . VAL C 1 435 ? -24.279 -0.035  -77.602  1.00 69.00  ? 435 VAL C CB    1 
ATOM   11542 C CG1   . VAL C 1 435 ? -24.189 1.387   -77.069  1.00 78.04  ? 435 VAL C CG1   1 
ATOM   11543 C CG2   . VAL C 1 435 ? -25.270 -0.130  -78.748  1.00 62.75  ? 435 VAL C CG2   1 
ATOM   11544 N N     . ILE C 1 436 ? -22.808 -2.736  -79.081  1.00 55.54  ? 436 ILE C N     1 
ATOM   11545 C CA    . ILE C 1 436 ? -22.750 -3.659  -80.197  1.00 60.05  ? 436 ILE C CA    1 
ATOM   11546 C C     . ILE C 1 436 ? -23.968 -4.573  -80.172  1.00 58.83  ? 436 ILE C C     1 
ATOM   11547 O O     . ILE C 1 436 ? -24.096 -5.401  -79.270  1.00 57.26  ? 436 ILE C O     1 
ATOM   11548 C CB    . ILE C 1 436 ? -21.469 -4.499  -80.128  1.00 61.80  ? 436 ILE C CB    1 
ATOM   11549 C CG1   . ILE C 1 436 ? -20.225 -3.606  -80.133  1.00 58.23  ? 436 ILE C CG1   1 
ATOM   11550 C CG2   . ILE C 1 436 ? -21.487 -5.522  -81.252  1.00 66.43  ? 436 ILE C CG2   1 
ATOM   11551 C CD1   . ILE C 1 436 ? -18.936 -4.343  -79.909  1.00 55.08  ? 436 ILE C CD1   1 
ATOM   11552 N N     . VAL C 1 437 ? -24.812 -4.429  -81.199  1.00 56.93  ? 437 VAL C N     1 
ATOM   11553 C CA    . VAL C 1 437 ? -26.040 -5.188  -81.333  1.00 60.30  ? 437 VAL C CA    1 
ATOM   11554 C C     . VAL C 1 437 ? -25.806 -6.405  -82.218  1.00 63.45  ? 437 VAL C C     1 
ATOM   11555 O O     . VAL C 1 437 ? -25.446 -6.269  -83.385  1.00 56.01  ? 437 VAL C O     1 
ATOM   11556 C CB    . VAL C 1 437 ? -27.139 -4.320  -81.940  1.00 61.17  ? 437 VAL C CB    1 
ATOM   11557 C CG1   . VAL C 1 437 ? -28.390 -5.140  -82.181  1.00 68.32  ? 437 VAL C CG1   1 
ATOM   11558 C CG2   . VAL C 1 437 ? -27.427 -3.116  -81.063  1.00 64.47  ? 437 VAL C CG2   1 
ATOM   11559 N N     . TYR C 1 438 ? -26.052 -7.588  -81.660  1.00 63.09  ? 438 TYR C N     1 
ATOM   11560 C CA    . TYR C 1 438 ? -25.748 -8.815  -82.368  1.00 68.18  ? 438 TYR C CA    1 
ATOM   11561 C C     . TYR C 1 438 ? -26.922 -9.782  -82.239  1.00 80.20  ? 438 TYR C C     1 
ATOM   11562 O O     . TYR C 1 438 ? -27.676 -9.709  -81.269  1.00 102.13 ? 438 TYR C O     1 
ATOM   11563 C CB    . TYR C 1 438 ? -24.441 -9.396  -81.832  1.00 62.23  ? 438 TYR C CB    1 
ATOM   11564 C CG    . TYR C 1 438 ? -24.527 -9.924  -80.429  1.00 63.88  ? 438 TYR C CG    1 
ATOM   11565 C CD1   . TYR C 1 438 ? -24.688 -9.052  -79.367  1.00 70.00  ? 438 TYR C CD1   1 
ATOM   11566 C CD2   . TYR C 1 438 ? -24.493 -11.290 -80.165  1.00 65.47  ? 438 TYR C CD2   1 
ATOM   11567 C CE1   . TYR C 1 438 ? -24.790 -9.517  -78.065  1.00 74.09  ? 438 TYR C CE1   1 
ATOM   11568 C CE2   . TYR C 1 438 ? -24.589 -11.773 -78.867  1.00 79.03  ? 438 TYR C CE2   1 
ATOM   11569 C CZ    . TYR C 1 438 ? -24.731 -10.877 -77.813  1.00 81.75  ? 438 TYR C CZ    1 
ATOM   11570 O OH    . TYR C 1 438 ? -24.826 -11.279 -76.501  1.00 85.52  ? 438 TYR C OH    1 
ATOM   11571 N N     . ASP C 1 439 ? -27.063 -10.688 -83.219  1.00 80.74  ? 439 ASP C N     1 
ATOM   11572 C CA    . ASP C 1 439 ? -28.081 -11.726 -83.168  1.00 83.17  ? 439 ASP C CA    1 
ATOM   11573 C C     . ASP C 1 439 ? -27.629 -12.771 -82.151  1.00 73.89  ? 439 ASP C C     1 
ATOM   11574 O O     . ASP C 1 439 ? -26.709 -13.525 -82.420  1.00 69.46  ? 439 ASP C O     1 
ATOM   11575 C CB    . ASP C 1 439 ? -28.353 -12.322 -84.558  1.00 91.55  ? 439 ASP C CB    1 
ATOM   11576 C CG    . ASP C 1 439 ? -29.548 -13.266 -84.647  1.00 96.28  ? 439 ASP C CG    1 
ATOM   11577 O OD1   . ASP C 1 439 ? -30.315 -13.356 -83.656  1.00 92.75  ? 439 ASP C OD1   1 
ATOM   11578 O OD2   . ASP C 1 439 ? -29.702 -13.917 -85.712  1.00 80.62  ? 439 ASP C OD2   1 
ATOM   11579 N N     . LYS C 1 440 ? -28.283 -12.776 -80.984  1.00 87.10  ? 440 LYS C N     1 
ATOM   11580 C CA    . LYS C 1 440 ? -28.103 -13.778 -79.946  1.00 99.56  ? 440 LYS C CA    1 
ATOM   11581 C C     . LYS C 1 440 ? -28.136 -15.198 -80.523  1.00 106.46 ? 440 LYS C C     1 
ATOM   11582 O O     . LYS C 1 440 ? -27.345 -16.045 -80.101  1.00 103.53 ? 440 LYS C O     1 
ATOM   11583 C CB    . LYS C 1 440 ? -29.217 -13.622 -78.899  1.00 116.29 ? 440 LYS C CB    1 
ATOM   11584 C CG    . LYS C 1 440 ? -29.274 -14.721 -77.839  1.00 129.64 ? 440 LYS C CG    1 
ATOM   11585 C CD    . LYS C 1 440 ? -30.668 -15.090 -77.319  1.00 116.73 ? 440 LYS C CD    1 
ATOM   11586 C CE    . LYS C 1 440 ? -30.666 -16.403 -76.555  1.00 101.23 ? 440 LYS C CE    1 
ATOM   11587 N NZ    . LYS C 1 440 ? -31.765 -16.470 -75.570  1.00 94.98  ? 440 LYS C NZ    1 
ATOM   11588 N N     . THR C 1 441 ? -29.075 -15.460 -81.457  1.00 112.04 ? 441 THR C N     1 
ATOM   11589 C CA    . THR C 1 441 ? -29.417 -16.815 -81.887  1.00 102.08 ? 441 THR C CA    1 
ATOM   11590 C C     . THR C 1 441 ? -28.231 -17.470 -82.595  1.00 93.72  ? 441 THR C C     1 
ATOM   11591 O O     . THR C 1 441 ? -27.844 -18.586 -82.256  1.00 89.17  ? 441 THR C O     1 
ATOM   11592 C CB    . THR C 1 441 ? -30.671 -16.858 -82.783  1.00 92.81  ? 441 THR C CB    1 
ATOM   11593 O OG1   . THR C 1 441 ? -30.414 -16.215 -84.035  1.00 91.35  ? 441 THR C OG1   1 
ATOM   11594 C CG2   . THR C 1 441 ? -31.888 -16.232 -82.133  1.00 83.53  ? 441 THR C CG2   1 
ATOM   11595 N N     . ASP C 1 442 ? -27.646 -16.751 -83.556  1.00 81.69  ? 442 ASP C N     1 
ATOM   11596 C CA    . ASP C 1 442 ? -26.665 -17.324 -84.458  1.00 89.32  ? 442 ASP C CA    1 
ATOM   11597 C C     . ASP C 1 442 ? -25.343 -17.578 -83.726  1.00 90.65  ? 442 ASP C C     1 
ATOM   11598 O O     . ASP C 1 442 ? -24.774 -16.654 -83.157  1.00 91.60  ? 442 ASP C O     1 
ATOM   11599 C CB    . ASP C 1 442 ? -26.468 -16.389 -85.649  1.00 88.48  ? 442 ASP C CB    1 
ATOM   11600 C CG    . ASP C 1 442 ? -25.563 -16.976 -86.713  1.00 89.65  ? 442 ASP C CG    1 
ATOM   11601 O OD1   . ASP C 1 442 ? -25.160 -18.152 -86.558  1.00 81.11  ? 442 ASP C OD1   1 
ATOM   11602 O OD2   . ASP C 1 442 ? -25.263 -16.245 -87.677  1.00 97.77  ? 442 ASP C OD2   1 
ATOM   11603 N N     . PRO C 1 443 ? -24.818 -18.827 -83.691  1.00 90.72  ? 443 PRO C N     1 
ATOM   11604 C CA    . PRO C 1 443 ? -23.479 -19.108 -83.149  1.00 93.05  ? 443 PRO C CA    1 
ATOM   11605 C C     . PRO C 1 443 ? -22.262 -18.539 -83.885  1.00 85.88  ? 443 PRO C C     1 
ATOM   11606 O O     . PRO C 1 443 ? -21.172 -18.436 -83.322  1.00 78.35  ? 443 PRO C O     1 
ATOM   11607 C CB    . PRO C 1 443 ? -23.386 -20.645 -83.219  1.00 94.44  ? 443 PRO C CB    1 
ATOM   11608 C CG    . PRO C 1 443 ? -24.828 -21.094 -83.181  1.00 95.67  ? 443 PRO C CG    1 
ATOM   11609 C CD    . PRO C 1 443 ? -25.534 -20.062 -84.036  1.00 96.51  ? 443 PRO C CD    1 
ATOM   11610 N N     . ASP C 1 444 ? -22.433 -18.204 -85.164  1.00 89.81  ? 444 ASP C N     1 
ATOM   11611 C CA    . ASP C 1 444 ? -21.334 -17.684 -85.956  1.00 87.88  ? 444 ASP C CA    1 
ATOM   11612 C C     . ASP C 1 444 ? -21.144 -16.222 -85.574  1.00 77.50  ? 444 ASP C C     1 
ATOM   11613 O O     . ASP C 1 444 ? -20.022 -15.750 -85.489  1.00 82.22  ? 444 ASP C O     1 
ATOM   11614 C CB    . ASP C 1 444 ? -21.565 -17.926 -87.456  1.00 105.52 ? 444 ASP C CB    1 
ATOM   11615 C CG    . ASP C 1 444 ? -21.817 -19.391 -87.813  1.00 116.15 ? 444 ASP C CG    1 
ATOM   11616 O OD1   . ASP C 1 444 ? -20.891 -20.209 -87.610  1.00 101.72 ? 444 ASP C OD1   1 
ATOM   11617 O OD2   . ASP C 1 444 ? -22.953 -19.721 -88.267  1.00 101.49 ? 444 ASP C OD2   1 
ATOM   11618 N N     . GLU C 1 445 ? -22.250 -15.517 -85.322  1.00 80.36  ? 445 GLU C N     1 
ATOM   11619 C CA    . GLU C 1 445 ? -22.203 -14.117 -84.928  1.00 86.21  ? 445 GLU C CA    1 
ATOM   11620 C C     . GLU C 1 445 ? -21.758 -13.995 -83.466  1.00 85.12  ? 445 GLU C C     1 
ATOM   11621 O O     . GLU C 1 445 ? -21.166 -12.986 -83.084  1.00 82.00  ? 445 GLU C O     1 
ATOM   11622 C CB    . GLU C 1 445 ? -23.552 -13.442 -85.203  1.00 87.18  ? 445 GLU C CB    1 
ATOM   11623 C CG    . GLU C 1 445 ? -23.706 -12.926 -86.628  1.00 89.75  ? 445 GLU C CG    1 
ATOM   11624 C CD    . GLU C 1 445 ? -23.540 -11.420 -86.782  1.00 108.14 ? 445 GLU C CD    1 
ATOM   11625 O OE1   . GLU C 1 445 ? -24.233 -10.685 -86.038  1.00 108.76 ? 445 GLU C OE1   1 
ATOM   11626 O OE2   . GLU C 1 445 ? -22.745 -10.977 -87.656  1.00 105.84 ? 445 GLU C OE2   1 
ATOM   11627 N N     . ARG C 1 446 ? -22.005 -15.031 -82.657  1.00 76.03  ? 446 ARG C N     1 
ATOM   11628 C CA    . ARG C 1 446 ? -21.560 -15.046 -81.274  1.00 73.09  ? 446 ARG C CA    1 
ATOM   11629 C C     . ARG C 1 446 ? -20.060 -15.343 -81.146  1.00 78.76  ? 446 ARG C C     1 
ATOM   11630 O O     . ARG C 1 446 ? -19.483 -15.052 -80.101  1.00 90.04  ? 446 ARG C O     1 
ATOM   11631 C CB    . ARG C 1 446 ? -22.315 -16.113 -80.477  1.00 74.47  ? 446 ARG C CB    1 
ATOM   11632 C CG    . ARG C 1 446 ? -23.782 -15.822 -80.201  1.00 71.89  ? 446 ARG C CG    1 
ATOM   11633 C CD    . ARG C 1 446 ? -24.319 -16.746 -79.112  1.00 75.71  ? 446 ARG C CD    1 
ATOM   11634 N NE    . ARG C 1 446 ? -24.001 -18.160 -79.321  1.00 84.16  ? 446 ARG C NE    1 
ATOM   11635 C CZ    . ARG C 1 446 ? -24.898 -19.128 -79.466  1.00 80.21  ? 446 ARG C CZ    1 
ATOM   11636 N NH1   . ARG C 1 446 ? -26.183 -18.870 -79.314  1.00 80.69  ? 446 ARG C NH1   1 
ATOM   11637 N NH2   . ARG C 1 446 ? -24.504 -20.353 -79.760  1.00 76.68  ? 446 ARG C NH2   1 
ATOM   11638 N N     . LYS C 1 447 ? -19.442 -15.988 -82.149  1.00 82.91  ? 447 LYS C N     1 
ATOM   11639 C CA    . LYS C 1 447 ? -17.997 -16.201 -82.168  1.00 77.65  ? 447 LYS C CA    1 
ATOM   11640 C C     . LYS C 1 447 ? -17.308 -14.910 -82.631  1.00 66.89  ? 447 LYS C C     1 
ATOM   11641 O O     . LYS C 1 447 ? -16.335 -14.473 -82.031  1.00 66.15  ? 447 LYS C O     1 
ATOM   11642 C CB    . LYS C 1 447 ? -17.625 -17.402 -83.048  1.00 82.73  ? 447 LYS C CB    1 
ATOM   11643 C CG    . LYS C 1 447 ? -16.395 -18.190 -82.602  1.00 92.70  ? 447 LYS C CG    1 
ATOM   11644 C CD    . LYS C 1 447 ? -16.149 -19.454 -83.435  1.00 112.93 ? 447 LYS C CD    1 
ATOM   11645 C CE    . LYS C 1 447 ? -15.639 -20.665 -82.664  1.00 117.19 ? 447 LYS C CE    1 
ATOM   11646 N NZ    . LYS C 1 447 ? -14.165 -20.817 -82.737  1.00 112.44 ? 447 LYS C NZ    1 
ATOM   11647 N N     . LYS C 1 448 ? -17.832 -14.281 -83.688  1.00 67.66  ? 448 LYS C N     1 
ATOM   11648 C CA    . LYS C 1 448 ? -17.336 -12.999 -84.162  1.00 73.75  ? 448 LYS C CA    1 
ATOM   11649 C C     . LYS C 1 448 ? -17.340 -11.984 -83.015  1.00 72.47  ? 448 LYS C C     1 
ATOM   11650 O O     . LYS C 1 448 ? -16.365 -11.274 -82.818  1.00 65.92  ? 448 LYS C O     1 
ATOM   11651 C CB    . LYS C 1 448 ? -18.165 -12.486 -85.352  1.00 77.98  ? 448 LYS C CB    1 
ATOM   11652 C CG    . LYS C 1 448 ? -17.906 -13.176 -86.691  1.00 91.65  ? 448 LYS C CG    1 
ATOM   11653 C CD    . LYS C 1 448 ? -18.965 -12.924 -87.778  1.00 96.84  ? 448 LYS C CD    1 
ATOM   11654 C CE    . LYS C 1 448 ? -18.698 -11.713 -88.652  1.00 94.67  ? 448 LYS C CE    1 
ATOM   11655 N NZ    . LYS C 1 448 ? -19.960 -11.091 -89.125  1.00 89.88  ? 448 LYS C NZ    1 
ATOM   11656 N N     . LEU C 1 449 ? -18.448 -11.900 -82.267  1.00 80.57  ? 449 LEU C N     1 
ATOM   11657 C CA    . LEU C 1 449 ? -18.599 -10.889 -81.232  1.00 70.82  ? 449 LEU C CA    1 
ATOM   11658 C C     . LEU C 1 449 ? -17.543 -11.068 -80.146  1.00 60.64  ? 449 LEU C C     1 
ATOM   11659 O O     . LEU C 1 449 ? -16.934 -10.104 -79.708  1.00 52.78  ? 449 LEU C O     1 
ATOM   11660 C CB    . LEU C 1 449 ? -19.991 -10.971 -80.599  1.00 68.22  ? 449 LEU C CB    1 
ATOM   11661 C CG    . LEU C 1 449 ? -20.191 -10.011 -79.425  1.00 70.81  ? 449 LEU C CG    1 
ATOM   11662 C CD1   . LEU C 1 449 ? -20.444 -8.593  -79.924  1.00 66.37  ? 449 LEU C CD1   1 
ATOM   11663 C CD2   . LEU C 1 449 ? -21.316 -10.476 -78.517  1.00 70.17  ? 449 LEU C CD2   1 
ATOM   11664 N N     . ASP C 1 450 ? -17.383 -12.304 -79.684  1.00 64.11  ? 450 ASP C N     1 
ATOM   11665 C CA    . ASP C 1 450 ? -16.468 -12.592 -78.604  1.00 63.51  ? 450 ASP C CA    1 
ATOM   11666 C C     . ASP C 1 450 ? -15.055 -12.223 -79.035  1.00 70.41  ? 450 ASP C C     1 
ATOM   11667 O O     . ASP C 1 450 ? -14.284 -11.675 -78.255  1.00 68.14  ? 450 ASP C O     1 
ATOM   11668 C CB    . ASP C 1 450 ? -16.554 -14.051 -78.186  1.00 59.30  ? 450 ASP C CB    1 
ATOM   11669 C CG    . ASP C 1 450 ? -15.702 -14.310 -76.963  1.00 69.87  ? 450 ASP C CG    1 
ATOM   11670 O OD1   . ASP C 1 450 ? -15.903 -13.604 -75.945  1.00 70.55  ? 450 ASP C OD1   1 
ATOM   11671 O OD2   . ASP C 1 450 ? -14.844 -15.197 -77.041  1.00 75.53  ? 450 ASP C OD2   1 
ATOM   11672 N N     . GLU C 1 451 ? -14.736 -12.504 -80.295  1.00 76.27  ? 451 GLU C N     1 
ATOM   11673 C CA    . GLU C 1 451 ? -13.404 -12.264 -80.820  1.00 78.19  ? 451 GLU C CA    1 
ATOM   11674 C C     . GLU C 1 451 ? -13.120 -10.753 -80.856  1.00 72.54  ? 451 GLU C C     1 
ATOM   11675 O O     . GLU C 1 451 ? -11.981 -10.329 -80.642  1.00 73.31  ? 451 GLU C O     1 
ATOM   11676 C CB    . GLU C 1 451 ? -13.319 -12.969 -82.177  1.00 82.69  ? 451 GLU C CB    1 
ATOM   11677 C CG    . GLU C 1 451 ? -11.903 -13.165 -82.684  1.00 106.31 ? 451 GLU C CG    1 
ATOM   11678 C CD    . GLU C 1 451 ? -11.827 -13.671 -84.116  1.00 115.41 ? 451 GLU C CD    1 
ATOM   11679 O OE1   . GLU C 1 451 ? -12.482 -14.710 -84.397  1.00 110.63 ? 451 GLU C OE1   1 
ATOM   11680 O OE2   . GLU C 1 451 ? -11.118 -13.025 -84.947  1.00 92.48  ? 451 GLU C OE2   1 
ATOM   11681 N N     . LEU C 1 452 ? -14.176 -9.957  -81.102  1.00 64.46  ? 452 LEU C N     1 
ATOM   11682 C CA    . LEU C 1 452 ? -14.117 -8.514  -81.292  1.00 57.22  ? 452 LEU C CA    1 
ATOM   11683 C C     . LEU C 1 452 ? -14.036 -7.789  -79.958  1.00 62.77  ? 452 LEU C C     1 
ATOM   11684 O O     . LEU C 1 452 ? -13.285 -6.828  -79.800  1.00 63.93  ? 452 LEU C O     1 
ATOM   11685 C CB    . LEU C 1 452 ? -15.386 -8.057  -82.011  1.00 51.66  ? 452 LEU C CB    1 
ATOM   11686 C CG    . LEU C 1 452 ? -15.607 -6.547  -82.066  1.00 55.33  ? 452 LEU C CG    1 
ATOM   11687 C CD1   . LEU C 1 452 ? -14.573 -5.879  -82.956  1.00 54.69  ? 452 LEU C CD1   1 
ATOM   11688 C CD2   . LEU C 1 452 ? -17.005 -6.221  -82.571  1.00 57.56  ? 452 LEU C CD2   1 
ATOM   11689 N N     . PHE C 1 453 ? -14.883 -8.221  -79.028  1.00 61.83  ? 453 PHE C N     1 
ATOM   11690 C CA    . PHE C 1 453 ? -14.835 -7.718  -77.667  1.00 63.59  ? 453 PHE C CA    1 
ATOM   11691 C C     . PHE C 1 453 ? -13.425 -7.895  -77.081  1.00 58.18  ? 453 PHE C C     1 
ATOM   11692 O O     . PHE C 1 453 ? -12.923 -7.011  -76.399  1.00 54.52  ? 453 PHE C O     1 
ATOM   11693 C CB    . PHE C 1 453 ? -15.930 -8.381  -76.825  1.00 56.11  ? 453 PHE C CB    1 
ATOM   11694 C CG    . PHE C 1 453 ? -16.202 -7.653  -75.539  1.00 54.94  ? 453 PHE C CG    1 
ATOM   11695 C CD1   . PHE C 1 453 ? -17.081 -6.586  -75.510  1.00 61.30  ? 453 PHE C CD1   1 
ATOM   11696 C CD2   . PHE C 1 453 ? -15.524 -7.985  -74.378  1.00 58.56  ? 453 PHE C CD2   1 
ATOM   11697 C CE1   . PHE C 1 453 ? -17.295 -5.874  -74.344  1.00 59.81  ? 453 PHE C CE1   1 
ATOM   11698 C CE2   . PHE C 1 453 ? -15.750 -7.279  -73.208  1.00 63.22  ? 453 PHE C CE2   1 
ATOM   11699 C CZ    . PHE C 1 453 ? -16.626 -6.218  -73.198  1.00 63.10  ? 453 PHE C CZ    1 
ATOM   11700 N N     . ASN C 1 454 ? -12.755 -9.015  -77.376  1.00 59.66  ? 454 ASN C N     1 
ATOM   11701 C CA    . ASN C 1 454 ? -11.397 -9.245  -76.896  1.00 59.76  ? 454 ASN C CA    1 
ATOM   11702 C C     . ASN C 1 454 ? -10.433 -8.238  -77.524  1.00 61.48  ? 454 ASN C C     1 
ATOM   11703 O O     . ASN C 1 454 ? -9.523  -7.749  -76.860  1.00 59.08  ? 454 ASN C O     1 
ATOM   11704 C CB    . ASN C 1 454 ? -10.911 -10.680 -77.138  1.00 55.38  ? 454 ASN C CB    1 
ATOM   11705 C CG    . ASN C 1 454 ? -11.677 -11.705 -76.321  1.00 61.68  ? 454 ASN C CG    1 
ATOM   11706 O OD1   . ASN C 1 454 ? -11.663 -11.689 -75.090  1.00 59.06  ? 454 ASN C OD1   1 
ATOM   11707 N ND2   . ASN C 1 454 ? -12.384 -12.596 -76.999  1.00 78.14  ? 454 ASN C ND2   1 
ATOM   11708 N N     . ILE C 1 455 ? -10.630 -7.913  -78.801  1.00 55.28  ? 455 ILE C N     1 
ATOM   11709 C CA    . ILE C 1 455 ? -9.736  -6.957  -79.424  1.00 55.84  ? 455 ILE C CA    1 
ATOM   11710 C C     . ILE C 1 455 ? -9.987  -5.572  -78.829  1.00 46.44  ? 455 ILE C C     1 
ATOM   11711 O O     . ILE C 1 455 ? -9.041  -4.851  -78.569  1.00 47.09  ? 455 ILE C O     1 
ATOM   11712 C CB    . ILE C 1 455 ? -9.850  -7.006  -80.964  1.00 53.54  ? 455 ILE C CB    1 
ATOM   11713 C CG1   . ILE C 1 455 ? -9.357  -8.362  -81.482  1.00 51.71  ? 455 ILE C CG1   1 
ATOM   11714 C CG2   . ILE C 1 455 ? -9.120  -5.836  -81.636  1.00 47.49  ? 455 ILE C CG2   1 
ATOM   11715 C CD1   . ILE C 1 455 ? -9.968  -8.783  -82.823  1.00 54.68  ? 455 ILE C CD1   1 
ATOM   11716 N N     . LEU C 1 456 ? -11.246 -5.205  -78.595  1.00 48.83  ? 456 LEU C N     1 
ATOM   11717 C CA    . LEU C 1 456 ? -11.592 -3.895  -78.042  1.00 50.00  ? 456 LEU C CA    1 
ATOM   11718 C C     . LEU C 1 456 ? -10.939 -3.681  -76.676  1.00 47.41  ? 456 LEU C C     1 
ATOM   11719 O O     . LEU C 1 456 ? -10.389 -2.620  -76.425  1.00 47.63  ? 456 LEU C O     1 
ATOM   11720 C CB    . LEU C 1 456 ? -13.117 -3.796  -77.942  1.00 54.50  ? 456 LEU C CB    1 
ATOM   11721 C CG    . LEU C 1 456 ? -13.859 -3.712  -79.279  1.00 52.52  ? 456 LEU C CG    1 
ATOM   11722 C CD1   . LEU C 1 456 ? -15.343 -3.484  -79.061  1.00 54.55  ? 456 LEU C CD1   1 
ATOM   11723 C CD2   . LEU C 1 456 ? -13.294 -2.597  -80.143  1.00 46.93  ? 456 LEU C CD2   1 
ATOM   11724 N N     . VAL C 1 457 ? -10.932 -4.718  -75.834  1.00 46.88  ? 457 VAL C N     1 
ATOM   11725 C CA    . VAL C 1 457 ? -10.328 -4.636  -74.517  1.00 56.03  ? 457 VAL C CA    1 
ATOM   11726 C C     . VAL C 1 457 ? -8.803  -4.498  -74.588  1.00 55.42  ? 457 VAL C C     1 
ATOM   11727 O O     . VAL C 1 457 ? -8.260  -3.606  -73.930  1.00 52.47  ? 457 VAL C O     1 
ATOM   11728 C CB    . VAL C 1 457 ? -10.706 -5.850  -73.657  1.00 59.05  ? 457 VAL C CB    1 
ATOM   11729 C CG1   . VAL C 1 457 ? -9.816  -5.952  -72.412  1.00 52.96  ? 457 VAL C CG1   1 
ATOM   11730 C CG2   . VAL C 1 457 ? -12.191 -5.837  -73.312  1.00 55.79  ? 457 VAL C CG2   1 
ATOM   11731 N N     . ASP C 1 458 ? -8.129  -5.429  -75.293  1.00 55.11  ? 458 ASP C N     1 
ATOM   11732 C CA    . ASP C 1 458 ? -6.676  -5.412  -75.470  1.00 52.91  ? 458 ASP C CA    1 
ATOM   11733 C C     . ASP C 1 458 ? -6.215  -4.051  -75.985  1.00 53.58  ? 458 ASP C C     1 
ATOM   11734 O O     . ASP C 1 458 ? -5.301  -3.453  -75.423  1.00 54.32  ? 458 ASP C O     1 
ATOM   11735 C CB    . ASP C 1 458 ? -6.193  -6.511  -76.421  1.00 59.12  ? 458 ASP C CB    1 
ATOM   11736 C CG    . ASP C 1 458 ? -6.121  -7.916  -75.826  1.00 65.55  ? 458 ASP C CG    1 
ATOM   11737 O OD1   . ASP C 1 458 ? -6.353  -8.064  -74.626  1.00 73.96  ? 458 ASP C OD1   1 
ATOM   11738 O OD2   . ASP C 1 458 ? -5.827  -8.864  -76.575  1.00 78.07  ? 458 ASP C OD2   1 
ATOM   11739 N N     . GLU C 1 459 ? -6.901  -3.522  -77.004  1.00 55.24  ? 459 GLU C N     1 
ATOM   11740 C CA    . GLU C 1 459 ? -6.447  -2.300  -77.654  1.00 59.55  ? 459 GLU C CA    1 
ATOM   11741 C C     . GLU C 1 459 ? -6.723  -1.096  -76.759  1.00 52.26  ? 459 GLU C C     1 
ATOM   11742 O O     . GLU C 1 459 ? -5.895  -0.201  -76.702  1.00 48.93  ? 459 GLU C O     1 
ATOM   11743 C CB    . GLU C 1 459 ? -7.039  -2.111  -79.058  1.00 50.15  ? 459 GLU C CB    1 
ATOM   11744 C CG    . GLU C 1 459 ? -6.767  -3.317  -79.933  1.00 52.79  ? 459 GLU C CG    1 
ATOM   11745 C CD    . GLU C 1 459 ? -6.992  -3.119  -81.418  1.00 53.40  ? 459 GLU C CD    1 
ATOM   11746 O OE1   . GLU C 1 459 ? -7.948  -2.421  -81.780  1.00 58.13  ? 459 GLU C OE1   1 
ATOM   11747 O OE2   . GLU C 1 459 ? -6.207  -3.686  -82.197  1.00 58.94  ? 459 GLU C OE2   1 
ATOM   11748 N N     . ALA C 1 460 ? -7.877  -1.064  -76.097  1.00 46.53  ? 460 ALA C N     1 
ATOM   11749 C CA    . ALA C 1 460 ? -8.157  0.036   -75.184  1.00 51.18  ? 460 ALA C CA    1 
ATOM   11750 C C     . ALA C 1 460 ? -7.168  -0.024  -74.014  1.00 46.00  ? 460 ALA C C     1 
ATOM   11751 O O     . ALA C 1 460 ? -6.577  0.991   -73.639  1.00 39.95  ? 460 ALA C O     1 
ATOM   11752 C CB    . ALA C 1 460 ? -9.612  0.029   -74.733  1.00 46.62  ? 460 ALA C CB    1 
ATOM   11753 N N     . ALA C 1 461 ? -6.935  -1.222  -73.479  1.00 44.96  ? 461 ALA C N     1 
ATOM   11754 C CA    . ALA C 1 461 ? -6.022  -1.347  -72.348  1.00 63.30  ? 461 ALA C CA    1 
ATOM   11755 C C     . ALA C 1 461 ? -4.645  -0.799  -72.735  1.00 58.12  ? 461 ALA C C     1 
ATOM   11756 O O     . ALA C 1 461 ? -4.011  -0.059  -71.971  1.00 57.18  ? 461 ALA C O     1 
ATOM   11757 C CB    . ALA C 1 461 ? -5.948  -2.782  -71.860  1.00 62.37  ? 461 ALA C CB    1 
ATOM   11758 N N     . ALA C 1 462 ? -4.237  -1.106  -73.965  1.00 51.80  ? 462 ALA C N     1 
ATOM   11759 C CA    . ALA C 1 462 ? -2.904  -0.777  -74.438  1.00 56.67  ? 462 ALA C CA    1 
ATOM   11760 C C     . ALA C 1 462 ? -2.695  0.742   -74.512  1.00 54.33  ? 462 ALA C C     1 
ATOM   11761 O O     . ALA C 1 462 ? -1.565  1.208   -74.398  1.00 52.69  ? 462 ALA C O     1 
ATOM   11762 C CB    . ALA C 1 462 ? -2.671  -1.474  -75.758  1.00 54.71  ? 462 ALA C CB    1 
ATOM   11763 N N     . GLU C 1 463 ? -3.780  1.523   -74.630  1.00 48.41  ? 463 GLU C N     1 
ATOM   11764 C CA    . GLU C 1 463 ? -3.688  2.979   -74.594  1.00 49.59  ? 463 GLU C CA    1 
ATOM   11765 C C     . GLU C 1 463 ? -3.944  3.527   -73.174  1.00 47.47  ? 463 GLU C C     1 
ATOM   11766 O O     . GLU C 1 463 ? -4.020  4.739   -72.970  1.00 40.96  ? 463 GLU C O     1 
ATOM   11767 C CB    . GLU C 1 463 ? -4.680  3.573   -75.603  1.00 49.02  ? 463 GLU C CB    1 
ATOM   11768 C CG    . GLU C 1 463 ? -4.499  3.097   -77.053  1.00 53.61  ? 463 GLU C CG    1 
ATOM   11769 C CD    . GLU C 1 463 ? -3.133  3.279   -77.726  1.00 55.39  ? 463 GLU C CD    1 
ATOM   11770 O OE1   . GLU C 1 463 ? -2.535  4.383   -77.602  1.00 50.76  ? 463 GLU C OE1   1 
ATOM   11771 O OE2   . GLU C 1 463 ? -2.678  2.331   -78.430  1.00 53.14  ? 463 GLU C OE2   1 
ATOM   11772 N N     . GLY C 1 464 ? -4.109  2.636   -72.188  1.00 49.82  ? 464 GLY C N     1 
ATOM   11773 C CA    . GLY C 1 464 ? -4.334  3.035   -70.805  1.00 54.93  ? 464 GLY C CA    1 
ATOM   11774 C C     . GLY C 1 464 ? -5.803  3.342   -70.496  1.00 57.84  ? 464 GLY C C     1 
ATOM   11775 O O     . GLY C 1 464 ? -6.113  4.147   -69.615  1.00 68.82  ? 464 GLY C O     1 
ATOM   11776 N N     . TYR C 1 465 ? -6.718  2.697   -71.222  1.00 57.91  ? 465 TYR C N     1 
ATOM   11777 C CA    . TYR C 1 465 ? -8.148  2.876   -70.998  1.00 56.13  ? 465 TYR C CA    1 
ATOM   11778 C C     . TYR C 1 465 ? -8.739  1.564   -70.496  1.00 51.66  ? 465 TYR C C     1 
ATOM   11779 O O     . TYR C 1 465 ? -8.767  0.579   -71.232  1.00 52.89  ? 465 TYR C O     1 
ATOM   11780 C CB    . TYR C 1 465 ? -8.896  3.269   -72.273  1.00 49.64  ? 465 TYR C CB    1 
ATOM   11781 C CG    . TYR C 1 465 ? -8.330  4.400   -73.087  1.00 46.97  ? 465 TYR C CG    1 
ATOM   11782 C CD1   . TYR C 1 465 ? -7.914  5.615   -72.538  1.00 43.57  ? 465 TYR C CD1   1 
ATOM   11783 C CD2   . TYR C 1 465 ? -8.281  4.265   -74.466  1.00 50.43  ? 465 TYR C CD2   1 
ATOM   11784 C CE1   . TYR C 1 465 ? -7.432  6.646   -73.351  1.00 45.54  ? 465 TYR C CE1   1 
ATOM   11785 C CE2   . TYR C 1 465 ? -7.801  5.275   -75.293  1.00 49.96  ? 465 TYR C CE2   1 
ATOM   11786 C CZ    . TYR C 1 465 ? -7.387  6.476   -74.739  1.00 52.92  ? 465 TYR C CZ    1 
ATOM   11787 O OH    . TYR C 1 465 ? -6.963  7.390   -75.680  1.00 46.54  ? 465 TYR C OH    1 
ATOM   11788 N N     . GLY C 1 466 ? -9.196  1.566   -69.239  1.00 54.84  ? 466 GLY C N     1 
ATOM   11789 C CA    . GLY C 1 466 ? -9.705  0.365   -68.595  1.00 51.89  ? 466 GLY C CA    1 
ATOM   11790 C C     . GLY C 1 466 ? -11.199 0.484   -68.348  1.00 49.00  ? 466 GLY C C     1 
ATOM   11791 O O     . GLY C 1 466 ? -11.685 1.577   -68.127  1.00 51.19  ? 466 GLY C O     1 
ATOM   11792 N N     . GLU C 1 467 ? -11.898 -0.649  -68.401  1.00 57.68  ? 467 GLU C N     1 
ATOM   11793 C CA    . GLU C 1 467 ? -13.341 -0.739  -68.206  1.00 51.82  ? 467 GLU C CA    1 
ATOM   11794 C C     . GLU C 1 467 ? -13.679 -0.573  -66.711  1.00 53.06  ? 467 GLU C C     1 
ATOM   11795 O O     . GLU C 1 467 ? -12.889 -0.897  -65.836  1.00 49.26  ? 467 GLU C O     1 
ATOM   11796 C CB    . GLU C 1 467 ? -13.766 -2.090  -68.807  1.00 51.36  ? 467 GLU C CB    1 
ATOM   11797 C CG    . GLU C 1 467 ? -15.254 -2.426  -68.734  1.00 52.88  ? 467 GLU C CG    1 
ATOM   11798 C CD    . GLU C 1 467 ? -16.205 -1.454  -69.423  1.00 56.28  ? 467 GLU C CD    1 
ATOM   11799 O OE1   . GLU C 1 467 ? -16.284 -0.273  -68.973  1.00 55.62  ? 467 GLU C OE1   1 
ATOM   11800 O OE2   . GLU C 1 467 ? -16.889 -1.873  -70.406  1.00 56.30  ? 467 GLU C OE2   1 
ATOM   11801 N N     . TYR C 1 468 ? -14.872 -0.055  -66.405  1.00 57.15  ? 468 TYR C N     1 
ATOM   11802 C CA    . TYR C 1 468 ? -15.319 0.089   -65.033  1.00 54.90  ? 468 TYR C CA    1 
ATOM   11803 C C     . TYR C 1 468 ? -16.531 -0.787  -64.738  1.00 59.37  ? 468 TYR C C     1 
ATOM   11804 O O     . TYR C 1 468 ? -16.925 -0.905  -63.580  1.00 63.69  ? 468 TYR C O     1 
ATOM   11805 C CB    . TYR C 1 468 ? -15.699 1.534   -64.734  1.00 51.77  ? 468 TYR C CB    1 
ATOM   11806 C CG    . TYR C 1 468 ? -17.040 1.971   -65.251  1.00 51.11  ? 468 TYR C CG    1 
ATOM   11807 C CD1   . TYR C 1 468 ? -17.194 2.404   -66.549  1.00 59.50  ? 468 TYR C CD1   1 
ATOM   11808 C CD2   . TYR C 1 468 ? -18.144 2.006   -64.427  1.00 55.79  ? 468 TYR C CD2   1 
ATOM   11809 C CE1   . TYR C 1 468 ? -18.415 2.850   -67.023  1.00 65.92  ? 468 TYR C CE1   1 
ATOM   11810 C CE2   . TYR C 1 468 ? -19.379 2.443   -64.882  1.00 59.45  ? 468 TYR C CE2   1 
ATOM   11811 C CZ    . TYR C 1 468 ? -19.518 2.854   -66.193  1.00 63.67  ? 468 TYR C CZ    1 
ATOM   11812 O OH    . TYR C 1 468 ? -20.724 3.288   -66.681  1.00 56.85  ? 468 TYR C OH    1 
ATOM   11813 N N     . ARG C 1 469 ? -17.107 -1.393  -65.782  1.00 63.35  ? 469 ARG C N     1 
ATOM   11814 C CA    . ARG C 1 469 ? -18.290 -2.231  -65.661  1.00 58.79  ? 469 ARG C CA    1 
ATOM   11815 C C     . ARG C 1 469 ? -18.344 -3.229  -66.803  1.00 59.95  ? 469 ARG C C     1 
ATOM   11816 O O     . ARG C 1 469 ? -18.254 -2.806  -67.948  1.00 60.16  ? 469 ARG C O     1 
ATOM   11817 C CB    . ARG C 1 469 ? -19.527 -1.357  -65.807  1.00 57.63  ? 469 ARG C CB    1 
ATOM   11818 C CG    . ARG C 1 469 ? -20.783 -2.064  -65.355  1.00 64.27  ? 469 ARG C CG    1 
ATOM   11819 C CD    . ARG C 1 469 ? -21.914 -1.081  -65.176  1.00 61.72  ? 469 ARG C CD    1 
ATOM   11820 N NE    . ARG C 1 469 ? -23.067 -1.864  -64.779  1.00 63.36  ? 469 ARG C NE    1 
ATOM   11821 C CZ    . ARG C 1 469 ? -24.310 -1.424  -64.824  1.00 65.10  ? 469 ARG C CZ    1 
ATOM   11822 N NH1   . ARG C 1 469 ? -24.542 -0.200  -65.269  1.00 52.95  ? 469 ARG C NH1   1 
ATOM   11823 N NH2   . ARG C 1 469 ? -25.298 -2.217  -64.432  1.00 78.14  ? 469 ARG C NH2   1 
ATOM   11824 N N     . THR C 1 470 ? -18.548 -4.520  -66.510  1.00 62.30  ? 470 THR C N     1 
ATOM   11825 C CA    . THR C 1 470 ? -18.467 -5.527  -67.560  1.00 60.77  ? 470 THR C CA    1 
ATOM   11826 C C     . THR C 1 470 ? -19.450 -6.673  -67.328  1.00 58.09  ? 470 THR C C     1 
ATOM   11827 O O     . THR C 1 470 ? -20.135 -6.717  -66.315  1.00 58.88  ? 470 THR C O     1 
ATOM   11828 C CB    . THR C 1 470 ? -17.038 -6.071  -67.704  1.00 65.98  ? 470 THR C CB    1 
ATOM   11829 O OG1   . THR C 1 470 ? -16.907 -6.743  -68.964  1.00 61.80  ? 470 THR C OG1   1 
ATOM   11830 C CG2   . THR C 1 470 ? -16.654 -6.998  -66.572  1.00 65.71  ? 470 THR C CG2   1 
ATOM   11831 N N     . HIS C 1 471 ? -19.484 -7.575  -68.322  1.00 56.35  ? 471 HIS C N     1 
ATOM   11832 C CA    . HIS C 1 471 ? -20.395 -8.702  -68.436  1.00 50.37  ? 471 HIS C CA    1 
ATOM   11833 C C     . HIS C 1 471 ? -19.754 -9.858  -67.683  1.00 50.83  ? 471 HIS C C     1 
ATOM   11834 O O     . HIS C 1 471 ? -18.521 -9.924  -67.612  1.00 48.11  ? 471 HIS C O     1 
ATOM   11835 C CB    . HIS C 1 471 ? -20.668 -8.957  -69.941  1.00 58.61  ? 471 HIS C CB    1 
ATOM   11836 C CG    . HIS C 1 471 ? -21.433 -10.190 -70.281  1.00 55.00  ? 471 HIS C CG    1 
ATOM   11837 N ND1   . HIS C 1 471 ? -20.975 -11.462 -70.007  1.00 63.02  ? 471 HIS C ND1   1 
ATOM   11838 C CD2   . HIS C 1 471 ? -22.679 -10.346 -70.786  1.00 63.63  ? 471 HIS C CD2   1 
ATOM   11839 C CE1   . HIS C 1 471 ? -21.911 -12.357 -70.345  1.00 67.82  ? 471 HIS C CE1   1 
ATOM   11840 N NE2   . HIS C 1 471 ? -22.969 -11.701 -70.804  1.00 64.51  ? 471 HIS C NE2   1 
ATOM   11841 N N     . ILE C 1 472 ? -20.588 -10.761 -67.134  1.00 57.51  ? 472 ILE C N     1 
ATOM   11842 C CA    . ILE C 1 472 ? -20.107 -11.852 -66.287  1.00 61.02  ? 472 ILE C CA    1 
ATOM   11843 C C     . ILE C 1 472 ? -18.994 -12.620 -66.995  1.00 65.67  ? 472 ILE C C     1 
ATOM   11844 O O     . ILE C 1 472 ? -18.061 -13.097 -66.347  1.00 64.67  ? 472 ILE C O     1 
ATOM   11845 C CB    . ILE C 1 472 ? -21.223 -12.822 -65.846  1.00 64.75  ? 472 ILE C CB    1 
ATOM   11846 C CG1   . ILE C 1 472 ? -22.056 -13.315 -67.031  1.00 73.69  ? 472 ILE C CG1   1 
ATOM   11847 C CG2   . ILE C 1 472 ? -22.104 -12.233 -64.753  1.00 63.71  ? 472 ILE C CG2   1 
ATOM   11848 C CD1   . ILE C 1 472 ? -22.911 -14.530 -66.711  1.00 80.95  ? 472 ILE C CD1   1 
ATOM   11849 N N     . ARG C 1 473 ? -19.109 -12.738 -68.323  1.00 62.79  ? 473 ARG C N     1 
ATOM   11850 C CA    . ARG C 1 473 ? -18.209 -13.565 -69.108  1.00 67.15  ? 473 ARG C CA    1 
ATOM   11851 C C     . ARG C 1 473 ? -16.784 -13.000 -69.074  1.00 59.24  ? 473 ARG C C     1 
ATOM   11852 O O     . ARG C 1 473 ? -15.835 -13.774 -69.106  1.00 52.07  ? 473 ARG C O     1 
ATOM   11853 C CB    . ARG C 1 473 ? -18.771 -13.703 -70.529  1.00 84.17  ? 473 ARG C CB    1 
ATOM   11854 C CG    . ARG C 1 473 ? -17.857 -14.413 -71.524  1.00 103.81 ? 473 ARG C CG    1 
ATOM   11855 C CD    . ARG C 1 473 ? -18.583 -14.806 -72.811  1.00 109.86 ? 473 ARG C CD    1 
ATOM   11856 N NE    . ARG C 1 473 ? -17.699 -15.316 -73.859  1.00 97.74  ? 473 ARG C NE    1 
ATOM   11857 C CZ    . ARG C 1 473 ? -16.973 -16.428 -73.771  1.00 97.78  ? 473 ARG C CZ    1 
ATOM   11858 N NH1   . ARG C 1 473 ? -17.015 -17.181 -72.688  1.00 103.21 ? 473 ARG C NH1   1 
ATOM   11859 N NH2   . ARG C 1 473 ? -16.202 -16.800 -74.776  1.00 93.22  ? 473 ARG C NH2   1 
ATOM   11860 N N     . TYR C 1 474 ? -16.640 -11.667 -68.973  1.00 51.66  ? 474 TYR C N     1 
ATOM   11861 C CA    . TYR C 1 474 ? -15.355 -11.007 -69.132  1.00 48.16  ? 474 TYR C CA    1 
ATOM   11862 C C     . TYR C 1 474 ? -14.843 -10.412 -67.825  1.00 50.62  ? 474 TYR C C     1 
ATOM   11863 O O     . TYR C 1 474 ? -13.970 -9.553  -67.855  1.00 55.39  ? 474 TYR C O     1 
ATOM   11864 C CB    . TYR C 1 474 ? -15.465 -9.878  -70.162  1.00 53.68  ? 474 TYR C CB    1 
ATOM   11865 C CG    . TYR C 1 474 ? -15.940 -10.336 -71.516  1.00 64.25  ? 474 TYR C CG    1 
ATOM   11866 C CD1   . TYR C 1 474 ? -15.123 -11.118 -72.317  1.00 68.02  ? 474 TYR C CD1   1 
ATOM   11867 C CD2   . TYR C 1 474 ? -17.218 -10.039 -71.977  1.00 62.39  ? 474 TYR C CD2   1 
ATOM   11868 C CE1   . TYR C 1 474 ? -15.551 -11.574 -73.552  1.00 69.11  ? 474 TYR C CE1   1 
ATOM   11869 C CE2   . TYR C 1 474 ? -17.663 -10.491 -73.210  1.00 60.99  ? 474 TYR C CE2   1 
ATOM   11870 C CZ    . TYR C 1 474 ? -16.822 -11.257 -73.999  1.00 68.54  ? 474 TYR C CZ    1 
ATOM   11871 O OH    . TYR C 1 474 ? -17.220 -11.725 -75.228  1.00 87.07  ? 474 TYR C OH    1 
ATOM   11872 N N     . MET C 1 475 ? -15.339 -10.853 -66.669  1.00 47.72  ? 475 MET C N     1 
ATOM   11873 C CA    . MET C 1 475 ? -14.876 -10.240 -65.434  1.00 46.91  ? 475 MET C CA    1 
ATOM   11874 C C     . MET C 1 475 ? -13.403 -10.555 -65.212  1.00 52.49  ? 475 MET C C     1 
ATOM   11875 O O     . MET C 1 475 ? -12.657 -9.664  -64.814  1.00 61.18  ? 475 MET C O     1 
ATOM   11876 C CB    . MET C 1 475 ? -15.687 -10.683 -64.217  1.00 43.45  ? 475 MET C CB    1 
ATOM   11877 C CG    . MET C 1 475 ? -17.038 -10.006 -64.181  1.00 45.36  ? 475 MET C CG    1 
ATOM   11878 S SD    . MET C 1 475 ? -18.237 -10.734 -63.054  1.00 47.81  ? 475 MET C SD    1 
ATOM   11879 C CE    . MET C 1 475 ? -19.612 -9.652  -63.451  1.00 51.04  ? 475 MET C CE    1 
ATOM   11880 N N     . ASP C 1 476 ? -12.987 -11.801 -65.470  1.00 56.14  ? 476 ASP C N     1 
ATOM   11881 C CA    . ASP C 1 476 ? -11.595 -12.177 -65.270  1.00 58.33  ? 476 ASP C CA    1 
ATOM   11882 C C     . ASP C 1 476 ? -10.699 -11.327 -66.170  1.00 69.28  ? 476 ASP C C     1 
ATOM   11883 O O     . ASP C 1 476 ? -9.700  -10.759 -65.700  1.00 58.86  ? 476 ASP C O     1 
ATOM   11884 C CB    . ASP C 1 476 ? -11.368 -13.672 -65.474  1.00 58.14  ? 476 ASP C CB    1 
ATOM   11885 C CG    . ASP C 1 476 ? -11.616 -14.510 -64.226  1.00 69.20  ? 476 ASP C CG    1 
ATOM   11886 O OD1   . ASP C 1 476 ? -11.771 -13.923 -63.133  1.00 64.39  ? 476 ASP C OD1   1 
ATOM   11887 O OD2   . ASP C 1 476 ? -11.659 -15.762 -64.346  1.00 75.96  ? 476 ASP C OD2   1 
ATOM   11888 N N     . ARG C 1 477 ? -11.109 -11.182 -67.442  1.00 69.11  ? 477 ARG C N     1 
ATOM   11889 C CA    . ARG C 1 477 ? -10.311 -10.457 -68.421  1.00 66.35  ? 477 ARG C CA    1 
ATOM   11890 C C     . ARG C 1 477 ? -10.083 -9.009  -67.979  1.00 56.24  ? 477 ARG C C     1 
ATOM   11891 O O     . ARG C 1 477 ? -8.942  -8.567  -67.903  1.00 56.24  ? 477 ARG C O     1 
ATOM   11892 C CB    . ARG C 1 477 ? -10.957 -10.527 -69.807  1.00 69.75  ? 477 ARG C CB    1 
ATOM   11893 C CG    . ARG C 1 477 ? -9.953  -10.426 -70.943  1.00 79.29  ? 477 ARG C CG    1 
ATOM   11894 C CD    . ARG C 1 477 ? -10.661 -10.327 -72.280  1.00 101.38 ? 477 ARG C CD    1 
ATOM   11895 N NE    . ARG C 1 477 ? -9.887  -10.896 -73.376  1.00 104.26 ? 477 ARG C NE    1 
ATOM   11896 C CZ    . ARG C 1 477 ? -8.687  -10.475 -73.756  1.00 107.34 ? 477 ARG C CZ    1 
ATOM   11897 N NH1   . ARG C 1 477 ? -8.100  -9.485  -73.102  1.00 105.74 ? 477 ARG C NH1   1 
ATOM   11898 N NH2   . ARG C 1 477 ? -8.075  -11.056 -74.777  1.00 103.33 ? 477 ARG C NH2   1 
ATOM   11899 N N     . ILE C 1 478 ? -11.165 -8.281  -67.678  1.00 51.85  ? 478 ILE C N     1 
ATOM   11900 C CA    . ILE C 1 478 ? -11.090 -6.890  -67.253  1.00 47.76  ? 478 ILE C CA    1 
ATOM   11901 C C     . ILE C 1 478 ? -10.286 -6.751  -65.946  1.00 51.27  ? 478 ILE C C     1 
ATOM   11902 O O     . ILE C 1 478 ? -9.504  -5.802  -65.796  1.00 48.03  ? 478 ILE C O     1 
ATOM   11903 C CB    . ILE C 1 478 ? -12.498 -6.289  -67.095  1.00 44.71  ? 478 ILE C CB    1 
ATOM   11904 C CG1   . ILE C 1 478 ? -13.332 -6.355  -68.377  1.00 45.85  ? 478 ILE C CG1   1 
ATOM   11905 C CG2   . ILE C 1 478 ? -12.410 -4.879  -66.542  1.00 45.86  ? 478 ILE C CG2   1 
ATOM   11906 C CD1   . ILE C 1 478 ? -12.770 -5.600  -69.551  1.00 50.55  ? 478 ILE C CD1   1 
ATOM   11907 N N     . ALA C 1 479 ? -10.434 -7.690  -64.997  1.00 42.33  ? 479 ALA C N     1 
ATOM   11908 C CA    . ALA C 1 479 ? -9.597  -7.634  -63.801  1.00 48.78  ? 479 ALA C CA    1 
ATOM   11909 C C     . ALA C 1 479 ? -8.112  -7.757  -64.165  1.00 50.71  ? 479 ALA C C     1 
ATOM   11910 O O     . ALA C 1 479 ? -7.274  -7.041  -63.614  1.00 51.09  ? 479 ALA C O     1 
ATOM   11911 C CB    . ALA C 1 479 ? -9.997  -8.675  -62.769  1.00 47.79  ? 479 ALA C CB    1 
ATOM   11912 N N     . LYS C 1 480 ? -7.785  -8.634  -65.122  1.00 58.66  ? 480 LYS C N     1 
ATOM   11913 C CA    . LYS C 1 480 ? -6.389  -8.906  -65.445  1.00 58.08  ? 480 LYS C CA    1 
ATOM   11914 C C     . LYS C 1 480 ? -5.737  -7.666  -66.050  1.00 51.75  ? 480 LYS C C     1 
ATOM   11915 O O     . LYS C 1 480 ? -4.519  -7.583  -66.015  1.00 46.66  ? 480 LYS C O     1 
ATOM   11916 C CB    . LYS C 1 480 ? -6.227  -10.208 -66.245  1.00 58.47  ? 480 LYS C CB    1 
ATOM   11917 C CG    . LYS C 1 480 ? -6.232  -11.461 -65.354  1.00 68.25  ? 480 LYS C CG    1 
ATOM   11918 C CD    . LYS C 1 480 ? -6.113  -12.827 -66.058  1.00 80.83  ? 480 LYS C CD    1 
ATOM   11919 C CE    . LYS C 1 480 ? -7.424  -13.315 -66.651  1.00 86.28  ? 480 LYS C CE    1 
ATOM   11920 N NZ    . LYS C 1 480 ? -7.273  -14.503 -67.526  1.00 82.27  ? 480 LYS C NZ    1 
ATOM   11921 N N     . THR C 1 481 ? -6.530  -6.642  -66.417  1.00 52.60  ? 481 THR C N     1 
ATOM   11922 C CA    . THR C 1 481 ? -5.974  -5.403  -66.954  1.00 51.25  ? 481 THR C CA    1 
ATOM   11923 C C     . THR C 1 481 ? -5.551  -4.406  -65.868  1.00 51.11  ? 481 THR C C     1 
ATOM   11924 O O     . THR C 1 481 ? -4.921  -3.399  -66.186  1.00 55.28  ? 481 THR C O     1 
ATOM   11925 C CB    . THR C 1 481 ? -6.951  -4.737  -67.941  1.00 52.83  ? 481 THR C CB    1 
ATOM   11926 O OG1   . THR C 1 481 ? -8.077  -4.161  -67.255  1.00 46.97  ? 481 THR C OG1   1 
ATOM   11927 C CG2   . THR C 1 481 ? -7.387  -5.703  -69.032  1.00 45.36  ? 481 THR C CG2   1 
ATOM   11928 N N     . TYR C 1 482 ? -5.894  -4.665  -64.599  1.00 54.61  ? 482 TYR C N     1 
ATOM   11929 C CA    . TYR C 1 482 ? -5.540  -3.771  -63.500  1.00 54.14  ? 482 TYR C CA    1 
ATOM   11930 C C     . TYR C 1 482 ? -4.353  -4.377  -62.736  1.00 60.16  ? 482 TYR C C     1 
ATOM   11931 O O     . TYR C 1 482 ? -4.432  -4.702  -61.543  1.00 59.91  ? 482 TYR C O     1 
ATOM   11932 C CB    . TYR C 1 482 ? -6.778  -3.490  -62.631  1.00 57.28  ? 482 TYR C CB    1 
ATOM   11933 C CG    . TYR C 1 482 ? -7.805  -2.574  -63.259  1.00 51.42  ? 482 TYR C CG    1 
ATOM   11934 C CD1   . TYR C 1 482 ? -7.742  -1.187  -63.166  1.00 43.80  ? 482 TYR C CD1   1 
ATOM   11935 C CD2   . TYR C 1 482 ? -8.825  -3.127  -64.017  1.00 48.54  ? 482 TYR C CD2   1 
ATOM   11936 C CE1   . TYR C 1 482 ? -8.693  -0.390  -63.795  1.00 48.14  ? 482 TYR C CE1   1 
ATOM   11937 C CE2   . TYR C 1 482 ? -9.767  -2.348  -64.661  1.00 41.72  ? 482 TYR C CE2   1 
ATOM   11938 C CZ    . TYR C 1 482 ? -9.710  -0.980  -64.543  1.00 46.75  ? 482 TYR C CZ    1 
ATOM   11939 O OH    . TYR C 1 482 ? -10.700 -0.335  -65.249  1.00 50.48  ? 482 TYR C OH    1 
ATOM   11940 N N     . SER C 1 483 ? -3.217  -4.457  -63.441  1.00 57.72  ? 483 SER C N     1 
ATOM   11941 C CA    . SER C 1 483 ? -2.193  -5.453  -63.184  1.00 53.26  ? 483 SER C CA    1 
ATOM   11942 C C     . SER C 1 483 ? -0.959  -4.837  -62.522  1.00 48.29  ? 483 SER C C     1 
ATOM   11943 O O     . SER C 1 483 ? -0.007  -5.543  -62.176  1.00 53.91  ? 483 SER C O     1 
ATOM   11944 C CB    . SER C 1 483 ? -1.845  -6.116  -64.483  1.00 53.60  ? 483 SER C CB    1 
ATOM   11945 O OG    . SER C 1 483 ? -1.393  -5.133  -65.412  1.00 54.39  ? 483 SER C OG    1 
ATOM   11946 N N     . TRP C 1 484 ? -0.992  -3.528  -62.303  1.00 40.88  ? 484 TRP C N     1 
ATOM   11947 C CA    . TRP C 1 484 ? 0.113   -2.824  -61.670  1.00 46.41  ? 484 TRP C CA    1 
ATOM   11948 C C     . TRP C 1 484 ? 0.710   -3.567  -60.470  1.00 52.72  ? 484 TRP C C     1 
ATOM   11949 O O     . TRP C 1 484 ? 0.002   -4.036  -59.560  1.00 43.12  ? 484 TRP C O     1 
ATOM   11950 C CB    . TRP C 1 484 ? -0.337  -1.429  -61.267  1.00 45.15  ? 484 TRP C CB    1 
ATOM   11951 C CG    . TRP C 1 484 ? 0.789   -0.524  -60.895  1.00 50.63  ? 484 TRP C CG    1 
ATOM   11952 C CD1   . TRP C 1 484 ? 1.576   0.215   -61.728  1.00 45.74  ? 484 TRP C CD1   1 
ATOM   11953 C CD2   . TRP C 1 484 ? 1.241   -0.255  -59.556  1.00 53.48  ? 484 TRP C CD2   1 
ATOM   11954 N NE1   . TRP C 1 484 ? 2.453   0.968   -60.987  1.00 48.51  ? 484 TRP C NE1   1 
ATOM   11955 C CE2   . TRP C 1 484 ? 2.296   0.669   -59.660  1.00 48.77  ? 484 TRP C CE2   1 
ATOM   11956 C CE3   . TRP C 1 484 ? 0.847   -0.700  -58.291  1.00 50.86  ? 484 TRP C CE3   1 
ATOM   11957 C CZ2   . TRP C 1 484 ? 2.965   1.139   -58.538  1.00 53.19  ? 484 TRP C CZ2   1 
ATOM   11958 C CZ3   . TRP C 1 484 ? 1.494   -0.217  -57.177  1.00 51.08  ? 484 TRP C CZ3   1 
ATOM   11959 C CH2   . TRP C 1 484 ? 2.542   0.685   -57.306  1.00 55.39  ? 484 TRP C CH2   1 
ATOM   11960 N N     . ASN C 1 485 ? 2.053   -3.647  -60.496  1.00 50.61  ? 485 ASN C N     1 
ATOM   11961 C CA    . ASN C 1 485 ? 2.839   -4.291  -59.458  1.00 46.03  ? 485 ASN C CA    1 
ATOM   11962 C C     . ASN C 1 485 ? 2.384   -5.746  -59.283  1.00 53.59  ? 485 ASN C C     1 
ATOM   11963 O O     . ASN C 1 485 ? 2.017   -6.171  -58.189  1.00 62.28  ? 485 ASN C O     1 
ATOM   11964 C CB    . ASN C 1 485 ? 2.788   -3.438  -58.197  1.00 45.08  ? 485 ASN C CB    1 
ATOM   11965 C CG    . ASN C 1 485 ? 3.725   -3.935  -57.123  1.00 49.53  ? 485 ASN C CG    1 
ATOM   11966 O OD1   . ASN C 1 485 ? 4.670   -4.670  -57.409  1.00 52.43  ? 485 ASN C OD1   1 
ATOM   11967 N ND2   . ASN C 1 485 ? 3.484   -3.527  -55.889  1.00 45.06  ? 485 ASN C ND2   1 
ATOM   11968 N N     . ASP C 1 486 ? 2.440   -6.507  -60.386  1.00 51.86  ? 486 ASP C N     1 
ATOM   11969 C CA    . ASP C 1 486 ? 1.978   -7.888  -60.475  1.00 55.46  ? 486 ASP C CA    1 
ATOM   11970 C C     . ASP C 1 486 ? 0.614   -8.068  -59.799  1.00 50.18  ? 486 ASP C C     1 
ATOM   11971 O O     . ASP C 1 486 ? 0.469   -8.942  -58.952  1.00 54.41  ? 486 ASP C O     1 
ATOM   11972 C CB    . ASP C 1 486 ? 3.010   -8.903  -59.940  1.00 51.89  ? 486 ASP C CB    1 
ATOM   11973 C CG    . ASP C 1 486 ? 2.650   -10.380 -60.188  1.00 64.81  ? 486 ASP C CG    1 
ATOM   11974 O OD1   . ASP C 1 486 ? 1.882   -10.676 -61.138  1.00 70.45  ? 486 ASP C OD1   1 
ATOM   11975 O OD2   . ASP C 1 486 ? 3.073   -11.244 -59.391  1.00 61.33  ? 486 ASP C OD2   1 
ATOM   11976 N N     . ASN C 1 487 ? -0.399  -7.296  -60.209  1.00 49.33  ? 487 ASN C N     1 
ATOM   11977 C CA    . ASN C 1 487 ? -1.770  -7.445  -59.700  1.00 48.17  ? 487 ASN C CA    1 
ATOM   11978 C C     . ASN C 1 487 ? -1.834  -7.206  -58.185  1.00 45.95  ? 487 ASN C C     1 
ATOM   11979 O O     . ASN C 1 487 ? -2.458  -7.957  -57.442  1.00 49.54  ? 487 ASN C O     1 
ATOM   11980 C CB    . ASN C 1 487 ? -2.395  -8.820  -59.998  1.00 45.85  ? 487 ASN C CB    1 
ATOM   11981 C CG    . ASN C 1 487 ? -2.241  -9.286  -61.434  1.00 49.68  ? 487 ASN C CG    1 
ATOM   11982 O OD1   . ASN C 1 487 ? -1.747  -10.383 -61.673  1.00 56.96  ? 487 ASN C OD1   1 
ATOM   11983 N ND2   . ASN C 1 487 ? -2.662  -8.483  -62.398  1.00 49.77  ? 487 ASN C ND2   1 
ATOM   11984 N N     . ALA C 1 488 ? -1.141  -6.182  -57.709  1.00 47.11  ? 488 ALA C N     1 
ATOM   11985 C CA    . ALA C 1 488 ? -1.123  -5.890  -56.293  1.00 45.52  ? 488 ALA C CA    1 
ATOM   11986 C C     . ALA C 1 488 ? -2.551  -5.661  -55.803  1.00 48.28  ? 488 ALA C C     1 
ATOM   11987 O O     . ALA C 1 488 ? -2.901  -6.125  -54.713  1.00 48.66  ? 488 ALA C O     1 
ATOM   11988 C CB    . ALA C 1 488 ? -0.243  -4.696  -56.033  1.00 47.93  ? 488 ALA C CB    1 
ATOM   11989 N N     . LEU C 1 489 ? -3.383  -4.985  -56.612  1.00 47.32  ? 489 LEU C N     1 
ATOM   11990 C CA    . LEU C 1 489 ? -4.695  -4.606  -56.106  1.00 51.25  ? 489 LEU C CA    1 
ATOM   11991 C C     . LEU C 1 489 ? -5.569  -5.845  -55.965  1.00 49.12  ? 489 LEU C C     1 
ATOM   11992 O O     . LEU C 1 489 ? -6.265  -5.977  -54.962  1.00 50.02  ? 489 LEU C O     1 
ATOM   11993 C CB    . LEU C 1 489 ? -5.377  -3.532  -56.960  1.00 51.28  ? 489 LEU C CB    1 
ATOM   11994 C CG    . LEU C 1 489 ? -6.796  -3.132  -56.520  1.00 56.11  ? 489 LEU C CG    1 
ATOM   11995 C CD1   . LEU C 1 489 ? -6.862  -2.748  -55.045  1.00 58.85  ? 489 LEU C CD1   1 
ATOM   11996 C CD2   . LEU C 1 489 ? -7.326  -1.976  -57.352  1.00 50.16  ? 489 LEU C CD2   1 
ATOM   11997 N N     . TRP C 1 490 ? -5.515  -6.758  -56.940  1.00 51.84  ? 490 TRP C N     1 
ATOM   11998 C CA    . TRP C 1 490 ? -6.362  -7.949  -56.884  1.00 46.29  ? 490 TRP C CA    1 
ATOM   11999 C C     . TRP C 1 490 ? -5.900  -8.873  -55.768  1.00 43.89  ? 490 TRP C C     1 
ATOM   12000 O O     . TRP C 1 490 ? -6.732  -9.562  -55.190  1.00 46.20  ? 490 TRP C O     1 
ATOM   12001 C CB    . TRP C 1 490 ? -6.532  -8.681  -58.243  1.00 44.68  ? 490 TRP C CB    1 
ATOM   12002 C CG    . TRP C 1 490 ? -7.925  -8.465  -58.773  1.00 40.02  ? 490 TRP C CG    1 
ATOM   12003 C CD1   . TRP C 1 490 ? -8.945  -9.377  -58.828  1.00 38.45  ? 490 TRP C CD1   1 
ATOM   12004 C CD2   . TRP C 1 490 ? -8.503  -7.200  -59.154  1.00 35.07  ? 490 TRP C CD2   1 
ATOM   12005 N NE1   . TRP C 1 490 ? -10.113 -8.767  -59.222  1.00 39.68  ? 490 TRP C NE1   1 
ATOM   12006 C CE2   . TRP C 1 490 ? -9.866  -7.431  -59.434  1.00 39.60  ? 490 TRP C CE2   1 
ATOM   12007 C CE3   . TRP C 1 490 ? -8.008  -5.903  -59.277  1.00 34.15  ? 490 TRP C CE3   1 
ATOM   12008 C CZ2   . TRP C 1 490 ? -10.715 -6.407  -59.853  1.00 36.74  ? 490 TRP C CZ2   1 
ATOM   12009 C CZ3   . TRP C 1 490 ? -8.847  -4.887  -59.680  1.00 34.05  ? 490 TRP C CZ3   1 
ATOM   12010 C CH2   . TRP C 1 490 ? -10.186 -5.143  -59.964  1.00 36.12  ? 490 TRP C CH2   1 
ATOM   12011 N N     . LYS C 1 491 ? -4.601  -8.849  -55.434  1.00 48.16  ? 491 LYS C N     1 
ATOM   12012 C CA    . LYS C 1 491 ? -4.069  -9.693  -54.369  1.00 49.38  ? 491 LYS C CA    1 
ATOM   12013 C C     . LYS C 1 491 ? -4.587  -9.233  -53.014  1.00 45.10  ? 491 LYS C C     1 
ATOM   12014 O O     . LYS C 1 491 ? -4.891  -10.076 -52.188  1.00 45.15  ? 491 LYS C O     1 
ATOM   12015 C CB    . LYS C 1 491 ? -2.535  -9.659  -54.340  1.00 58.86  ? 491 LYS C CB    1 
ATOM   12016 C CG    . LYS C 1 491 ? -1.863  -10.511 -55.399  1.00 62.57  ? 491 LYS C CG    1 
ATOM   12017 C CD    . LYS C 1 491 ? -0.381  -10.310 -55.548  1.00 64.03  ? 491 LYS C CD    1 
ATOM   12018 C CE    . LYS C 1 491 ? 0.101   -11.075 -56.762  1.00 65.48  ? 491 LYS C CE    1 
ATOM   12019 N NZ    . LYS C 1 491 ? 1.572   -11.070 -56.875  1.00 69.90  ? 491 LYS C NZ    1 
ATOM   12020 N N     . MET C 1 492 ? -4.664  -7.905  -52.795  1.00 47.10  ? 492 MET C N     1 
ATOM   12021 C CA    . MET C 1 492 ? -5.317  -7.364  -51.612  1.00 47.01  ? 492 MET C CA    1 
ATOM   12022 C C     . MET C 1 492 ? -6.776  -7.813  -51.541  1.00 51.24  ? 492 MET C C     1 
ATOM   12023 O O     . MET C 1 492 ? -7.212  -8.254  -50.478  1.00 49.28  ? 492 MET C O     1 
ATOM   12024 C CB    . MET C 1 492 ? -5.274  -5.843  -51.582  1.00 47.46  ? 492 MET C CB    1 
ATOM   12025 C CG    . MET C 1 492 ? -5.723  -5.275  -50.268  1.00 49.34  ? 492 MET C CG    1 
ATOM   12026 S SD    . MET C 1 492 ? -5.898  -3.460  -50.245  1.00 52.43  ? 492 MET C SD    1 
ATOM   12027 C CE    . MET C 1 492 ? -7.425  -3.293  -51.163  1.00 55.42  ? 492 MET C CE    1 
ATOM   12028 N N     . HIS C 1 493 ? -7.514  -7.743  -52.665  1.00 51.37  ? 493 HIS C N     1 
ATOM   12029 C CA    . HIS C 1 493 ? -8.931  -8.099  -52.667  1.00 50.80  ? 493 HIS C CA    1 
ATOM   12030 C C     . HIS C 1 493 ? -9.132  -9.558  -52.265  1.00 51.86  ? 493 HIS C C     1 
ATOM   12031 O O     . HIS C 1 493 ? -10.129 -9.875  -51.623  1.00 54.24  ? 493 HIS C O     1 
ATOM   12032 C CB    . HIS C 1 493 ? -9.616  -7.913  -54.023  1.00 50.56  ? 493 HIS C CB    1 
ATOM   12033 C CG    . HIS C 1 493 ? -9.814  -6.512  -54.527  1.00 54.26  ? 493 HIS C CG    1 
ATOM   12034 N ND1   . HIS C 1 493 ? -10.219 -5.452  -53.751  1.00 49.54  ? 493 HIS C ND1   1 
ATOM   12035 C CD2   . HIS C 1 493 ? -9.703  -6.019  -55.792  1.00 52.99  ? 493 HIS C CD2   1 
ATOM   12036 C CE1   . HIS C 1 493 ? -10.342 -4.369  -54.519  1.00 53.46  ? 493 HIS C CE1   1 
ATOM   12037 N NE2   . HIS C 1 493 ? -10.023 -4.685  -55.754  1.00 52.74  ? 493 HIS C NE2   1 
ATOM   12038 N N     . GLU C 1 494 ? -8.195  -10.439 -52.652  1.00 50.02  ? 494 GLU C N     1 
ATOM   12039 C CA    . GLU C 1 494 ? -8.289  -11.863 -52.350  1.00 51.79  ? 494 GLU C CA    1 
ATOM   12040 C C     . GLU C 1 494 ? -8.053  -12.081 -50.848  1.00 52.64  ? 494 GLU C C     1 
ATOM   12041 O O     . GLU C 1 494 ? -8.645  -12.951 -50.219  1.00 63.40  ? 494 GLU C O     1 
ATOM   12042 C CB    . GLU C 1 494 ? -7.266  -12.694 -53.147  1.00 62.67  ? 494 GLU C CB    1 
ATOM   12043 C CG    . GLU C 1 494 ? -7.315  -12.601 -54.681  1.00 71.52  ? 494 GLU C CG    1 
ATOM   12044 C CD    . GLU C 1 494 ? -8.244  -13.524 -55.465  1.00 91.17  ? 494 GLU C CD    1 
ATOM   12045 O OE1   . GLU C 1 494 ? -8.974  -14.367 -54.841  1.00 89.31  ? 494 GLU C OE1   1 
ATOM   12046 O OE2   . GLU C 1 494 ? -8.261  -13.386 -56.726  1.00 92.23  ? 494 GLU C OE2   1 
ATOM   12047 N N     . THR C 1 495 ? -7.123  -11.315 -50.280  1.00 60.85  ? 495 THR C N     1 
ATOM   12048 C CA    . THR C 1 495 ? -6.860  -11.299 -48.851  1.00 57.35  ? 495 THR C CA    1 
ATOM   12049 C C     . THR C 1 495 ? -8.134  -10.977 -48.077  1.00 53.35  ? 495 THR C C     1 
ATOM   12050 O O     . THR C 1 495 ? -8.447  -11.650 -47.095  1.00 51.88  ? 495 THR C O     1 
ATOM   12051 C CB    . THR C 1 495 ? -5.818  -10.228 -48.515  1.00 57.41  ? 495 THR C CB    1 
ATOM   12052 O OG1   . THR C 1 495 ? -4.662  -10.560 -49.271  1.00 54.92  ? 495 THR C OG1   1 
ATOM   12053 C CG2   . THR C 1 495 ? -5.500  -10.157 -47.040  1.00 66.54  ? 495 THR C CG2   1 
ATOM   12054 N N     . ILE C 1 496 ? -8.829  -9.922  -48.527  1.00 48.63  ? 496 ILE C N     1 
ATOM   12055 C CA    . ILE C 1 496 ? -10.046 -9.473  -47.884  1.00 49.87  ? 496 ILE C CA    1 
ATOM   12056 C C     . ILE C 1 496 ? -11.105 -10.547 -48.058  1.00 42.52  ? 496 ILE C C     1 
ATOM   12057 O O     . ILE C 1 496 ? -11.733 -10.949 -47.078  1.00 47.78  ? 496 ILE C O     1 
ATOM   12058 C CB    . ILE C 1 496 ? -10.512 -8.104  -48.408  1.00 49.46  ? 496 ILE C CB    1 
ATOM   12059 C CG1   . ILE C 1 496 ? -9.511  -6.998  -48.077  1.00 44.64  ? 496 ILE C CG1   1 
ATOM   12060 C CG2   . ILE C 1 496 ? -11.890 -7.767  -47.876  1.00 47.17  ? 496 ILE C CG2   1 
ATOM   12061 C CD1   . ILE C 1 496 ? -9.867  -5.667  -48.714  1.00 44.15  ? 496 ILE C CD1   1 
ATOM   12062 N N     . LYS C 1 497 ? -11.206 -11.056 -49.282  1.00 40.62  ? 497 LYS C N     1 
ATOM   12063 C CA    . LYS C 1 497 ? -12.126 -12.140 -49.611  1.00 41.20  ? 497 LYS C CA    1 
ATOM   12064 C C     . LYS C 1 497 ? -11.921 -13.344 -48.709  1.00 38.75  ? 497 LYS C C     1 
ATOM   12065 O O     . LYS C 1 497 ? -12.882 -13.992 -48.298  1.00 43.76  ? 497 LYS C O     1 
ATOM   12066 C CB    . LYS C 1 497 ? -11.921 -12.613 -51.046  1.00 41.34  ? 497 LYS C CB    1 
ATOM   12067 C CG    . LYS C 1 497 ? -12.811 -13.770 -51.460  1.00 45.98  ? 497 LYS C CG    1 
ATOM   12068 C CD    . LYS C 1 497 ? -14.299 -13.524 -51.363  1.00 43.59  ? 497 LYS C CD    1 
ATOM   12069 C CE    . LYS C 1 497 ? -15.007 -14.448 -52.329  1.00 48.73  ? 497 LYS C CE    1 
ATOM   12070 N NZ    . LYS C 1 497 ? -16.479 -14.332 -52.284  1.00 54.55  ? 497 LYS C NZ    1 
ATOM   12071 N N     . ASP C 1 498 ? -10.664 -13.660 -48.427  1.00 37.58  ? 498 ASP C N     1 
ATOM   12072 C CA    . ASP C 1 498 ? -10.365 -14.853 -47.657  1.00 47.54  ? 498 ASP C CA    1 
ATOM   12073 C C     . ASP C 1 498 ? -10.747 -14.673 -46.171  1.00 55.15  ? 498 ASP C C     1 
ATOM   12074 O O     . ASP C 1 498 ? -11.055 -15.650 -45.484  1.00 57.90  ? 498 ASP C O     1 
ATOM   12075 C CB    . ASP C 1 498 ? -8.897  -15.240 -47.896  1.00 50.00  ? 498 ASP C CB    1 
ATOM   12076 C CG    . ASP C 1 498 ? -8.652  -16.037 -49.170  1.00 49.30  ? 498 ASP C CG    1 
ATOM   12077 O OD1   . ASP C 1 498 ? -9.639  -16.463 -49.788  1.00 55.48  ? 498 ASP C OD1   1 
ATOM   12078 O OD2   . ASP C 1 498 ? -7.480  -16.232 -49.538  1.00 50.70  ? 498 ASP C OD2   1 
ATOM   12079 N N     . ALA C 1 499 ? -10.712 -13.434 -45.656  1.00 51.72  ? 499 ALA C N     1 
ATOM   12080 C CA    . ALA C 1 499 ? -11.016 -13.157 -44.259  1.00 52.59  ? 499 ALA C CA    1 
ATOM   12081 C C     . ALA C 1 499 ? -12.523 -13.135 -44.019  1.00 51.95  ? 499 ALA C C     1 
ATOM   12082 O O     . ALA C 1 499 ? -12.993 -13.645 -43.014  1.00 51.99  ? 499 ALA C O     1 
ATOM   12083 C CB    . ALA C 1 499 ? -10.422 -11.824 -43.887  1.00 58.02  ? 499 ALA C CB    1 
ATOM   12084 N N     . LEU C 1 500 ? -13.261 -12.513 -44.946  1.00 51.92  ? 500 LEU C N     1 
ATOM   12085 C CA    . LEU C 1 500 ? -14.705 -12.400 -44.857  1.00 52.48  ? 500 LEU C CA    1 
ATOM   12086 C C     . LEU C 1 500 ? -15.368 -13.694 -45.324  1.00 51.65  ? 500 LEU C C     1 
ATOM   12087 O O     . LEU C 1 500 ? -16.430 -14.048 -44.833  1.00 49.71  ? 500 LEU C O     1 
ATOM   12088 C CB    . LEU C 1 500 ? -15.167 -11.227 -45.732  1.00 54.97  ? 500 LEU C CB    1 
ATOM   12089 C CG    . LEU C 1 500 ? -14.757 -9.819  -45.282  1.00 56.40  ? 500 LEU C CG    1 
ATOM   12090 C CD1   . LEU C 1 500 ? -15.186 -8.777  -46.307  1.00 58.58  ? 500 LEU C CD1   1 
ATOM   12091 C CD2   . LEU C 1 500 ? -15.333 -9.468  -43.913  1.00 52.28  ? 500 LEU C CD2   1 
ATOM   12092 N N     . ASP C 1 501 ? -14.782 -14.380 -46.307  1.00 54.64  ? 501 ASP C N     1 
ATOM   12093 C CA    . ASP C 1 501 ? -15.476 -15.493 -46.941  1.00 55.83  ? 501 ASP C CA    1 
ATOM   12094 C C     . ASP C 1 501 ? -14.559 -16.705 -47.078  1.00 53.53  ? 501 ASP C C     1 
ATOM   12095 O O     . ASP C 1 501 ? -14.245 -17.135 -48.188  1.00 43.65  ? 501 ASP C O     1 
ATOM   12096 C CB    . ASP C 1 501 ? -16.012 -15.081 -48.306  1.00 51.24  ? 501 ASP C CB    1 
ATOM   12097 C CG    . ASP C 1 501 ? -17.024 -16.057 -48.873  1.00 53.97  ? 501 ASP C CG    1 
ATOM   12098 O OD1   . ASP C 1 501 ? -17.294 -17.094 -48.209  1.00 56.81  ? 501 ASP C OD1   1 
ATOM   12099 O OD2   . ASP C 1 501 ? -17.537 -15.766 -49.980  1.00 56.50  ? 501 ASP C OD2   1 
ATOM   12100 N N     . PRO C 1 502 ? -14.120 -17.294 -45.942  1.00 54.17  ? 502 PRO C N     1 
ATOM   12101 C CA    . PRO C 1 502 ? -13.118 -18.354 -45.964  1.00 53.25  ? 502 PRO C CA    1 
ATOM   12102 C C     . PRO C 1 502 ? -13.563 -19.612 -46.703  1.00 49.15  ? 502 PRO C C     1 
ATOM   12103 O O     . PRO C 1 502 ? -12.715 -20.353 -47.185  1.00 53.84  ? 502 PRO C O     1 
ATOM   12104 C CB    . PRO C 1 502 ? -12.814 -18.623 -44.468  1.00 56.19  ? 502 PRO C CB    1 
ATOM   12105 C CG    . PRO C 1 502 ? -13.952 -18.007 -43.675  1.00 51.31  ? 502 PRO C CG    1 
ATOM   12106 C CD    . PRO C 1 502 ? -14.506 -16.918 -44.571  1.00 58.00  ? 502 PRO C CD    1 
ATOM   12107 N N     . ASN C 1 503 ? -14.879 -19.834 -46.804  1.00 56.54  ? 503 ASN C N     1 
ATOM   12108 C CA    . ASN C 1 503 ? -15.427 -21.014 -47.465  1.00 57.15  ? 503 ASN C CA    1 
ATOM   12109 C C     . ASN C 1 503 ? -15.805 -20.737 -48.924  1.00 59.88  ? 503 ASN C C     1 
ATOM   12110 O O     . ASN C 1 503 ? -16.230 -21.652 -49.639  1.00 54.00  ? 503 ASN C O     1 
ATOM   12111 C CB    . ASN C 1 503 ? -16.611 -21.583 -46.675  1.00 54.20  ? 503 ASN C CB    1 
ATOM   12112 C CG    . ASN C 1 503 ? -16.141 -22.105 -45.336  1.00 52.55  ? 503 ASN C CG    1 
ATOM   12113 O OD1   . ASN C 1 503 ? -15.040 -22.640 -45.254  1.00 52.98  ? 503 ASN C OD1   1 
ATOM   12114 N ND2   . ASN C 1 503 ? -16.919 -21.903 -44.286  1.00 46.03  ? 503 ASN C ND2   1 
ATOM   12115 N N     . GLY C 1 504 ? -15.608 -19.489 -49.364  1.00 57.64  ? 504 GLY C N     1 
ATOM   12116 C CA    . GLY C 1 504 ? -15.822 -19.105 -50.750  1.00 55.05  ? 504 GLY C CA    1 
ATOM   12117 C C     . GLY C 1 504 ? -17.231 -19.437 -51.233  1.00 52.91  ? 504 GLY C C     1 
ATOM   12118 O O     . GLY C 1 504 ? -17.366 -20.163 -52.210  1.00 69.59  ? 504 GLY C O     1 
ATOM   12119 N N     . ILE C 1 505 ? -18.263 -18.909 -50.561  1.00 48.45  ? 505 ILE C N     1 
ATOM   12120 C CA    . ILE C 1 505 ? -19.638 -19.269 -50.868  1.00 51.63  ? 505 ILE C CA    1 
ATOM   12121 C C     . ILE C 1 505 ? -20.414 -18.118 -51.513  1.00 50.55  ? 505 ILE C C     1 
ATOM   12122 O O     . ILE C 1 505 ? -21.508 -18.345 -52.012  1.00 54.17  ? 505 ILE C O     1 
ATOM   12123 C CB    . ILE C 1 505 ? -20.356 -19.834 -49.625  1.00 64.79  ? 505 ILE C CB    1 
ATOM   12124 C CG1   . ILE C 1 505 ? -20.154 -18.995 -48.364  1.00 66.77  ? 505 ILE C CG1   1 
ATOM   12125 C CG2   . ILE C 1 505 ? -19.941 -21.281 -49.382  1.00 69.75  ? 505 ILE C CG2   1 
ATOM   12126 C CD1   . ILE C 1 505 ? -21.078 -17.835 -48.271  1.00 71.18  ? 505 ILE C CD1   1 
ATOM   12127 N N     . LEU C 1 506 ? -19.865 -16.895 -51.515  1.00 47.13  ? 506 LEU C N     1 
ATOM   12128 C CA    . LEU C 1 506 ? -20.494 -15.763 -52.170  1.00 47.85  ? 506 LEU C CA    1 
ATOM   12129 C C     . LEU C 1 506 ? -19.857 -15.520 -53.536  1.00 51.95  ? 506 LEU C C     1 
ATOM   12130 O O     . LEU C 1 506 ? -18.721 -15.074 -53.622  1.00 46.01  ? 506 LEU C O     1 
ATOM   12131 C CB    . LEU C 1 506 ? -20.354 -14.506 -51.315  1.00 49.32  ? 506 LEU C CB    1 
ATOM   12132 C CG    . LEU C 1 506 ? -21.536 -14.144 -50.424  1.00 59.42  ? 506 LEU C CG    1 
ATOM   12133 C CD1   . LEU C 1 506 ? -21.395 -12.715 -49.932  1.00 62.21  ? 506 LEU C CD1   1 
ATOM   12134 C CD2   . LEU C 1 506 ? -22.870 -14.313 -51.141  1.00 63.34  ? 506 LEU C CD2   1 
ATOM   12135 N N     . ALA C 1 507 ? -20.624 -15.838 -54.586  1.00 63.02  ? 507 ALA C N     1 
ATOM   12136 C CA    . ALA C 1 507 ? -20.457 -15.322 -55.941  1.00 59.23  ? 507 ALA C CA    1 
ATOM   12137 C C     . ALA C 1 507 ? -19.030 -15.510 -56.458  1.00 48.31  ? 507 ALA C C     1 
ATOM   12138 O O     . ALA C 1 507 ? -18.411 -14.566 -56.949  1.00 42.88  ? 507 ALA C O     1 
ATOM   12139 C CB    . ALA C 1 507 ? -20.878 -13.866 -55.969  1.00 57.98  ? 507 ALA C CB    1 
ATOM   12140 N N     . PRO C 1 508 ? -18.470 -16.733 -56.430  1.00 49.53  ? 508 PRO C N     1 
ATOM   12141 C CA    . PRO C 1 508 ? -17.081 -16.928 -56.828  1.00 48.69  ? 508 PRO C CA    1 
ATOM   12142 C C     . PRO C 1 508 ? -16.976 -16.495 -58.275  1.00 52.78  ? 508 PRO C C     1 
ATOM   12143 O O     . PRO C 1 508 ? -17.858 -16.840 -59.068  1.00 60.06  ? 508 PRO C O     1 
ATOM   12144 C CB    . PRO C 1 508 ? -16.814 -18.419 -56.646  1.00 51.85  ? 508 PRO C CB    1 
ATOM   12145 C CG    . PRO C 1 508 ? -17.984 -18.919 -55.816  1.00 50.86  ? 508 PRO C CG    1 
ATOM   12146 C CD    . PRO C 1 508 ? -19.145 -18.005 -56.144  1.00 53.24  ? 508 PRO C CD    1 
ATOM   12147 N N     . GLY C 1 509 ? -15.955 -15.653 -58.523  1.00 55.87  ? 509 GLY C N     1 
ATOM   12148 C CA    . GLY C 1 509 ? -15.626 -15.079 -59.819  1.00 50.75  ? 509 GLY C CA    1 
ATOM   12149 C C     . GLY C 1 509 ? -15.991 -13.596 -59.965  1.00 56.29  ? 509 GLY C C     1 
ATOM   12150 O O     . GLY C 1 509 ? -15.477 -12.911 -60.853  1.00 73.67  ? 509 GLY C O     1 
ATOM   12151 N N     . LYS C 1 510 ? -16.921 -13.102 -59.146  1.00 51.77  ? 510 LYS C N     1 
ATOM   12152 C CA    . LYS C 1 510 ? -17.431 -11.747 -59.308  1.00 53.56  ? 510 LYS C CA    1 
ATOM   12153 C C     . LYS C 1 510 ? -16.251 -10.780 -59.330  1.00 49.80  ? 510 LYS C C     1 
ATOM   12154 O O     . LYS C 1 510 ? -15.357 -10.914 -58.498  1.00 52.50  ? 510 LYS C O     1 
ATOM   12155 C CB    . LYS C 1 510 ? -18.443 -11.494 -58.187  1.00 56.15  ? 510 LYS C CB    1 
ATOM   12156 C CG    . LYS C 1 510 ? -19.032 -10.104 -58.118  1.00 56.42  ? 510 LYS C CG    1 
ATOM   12157 C CD    . LYS C 1 510 ? -19.763 -9.664  -59.336  1.00 61.05  ? 510 LYS C CD    1 
ATOM   12158 C CE    . LYS C 1 510 ? -20.049 -8.171  -59.295  1.00 70.32  ? 510 LYS C CE    1 
ATOM   12159 N NZ    . LYS C 1 510 ? -20.005 -7.539  -60.642  1.00 67.33  ? 510 LYS C NZ    1 
ATOM   12160 N N     . SER C 1 511 ? -16.215 -9.892  -60.341  1.00 42.70  ? 511 SER C N     1 
ATOM   12161 C CA    . SER C 1 511 ? -15.156 -8.907  -60.552  1.00 44.81  ? 511 SER C CA    1 
ATOM   12162 C C     . SER C 1 511 ? -13.766 -9.557  -60.612  1.00 45.94  ? 511 SER C C     1 
ATOM   12163 O O     . SER C 1 511 ? -12.746 -8.879  -60.505  1.00 46.40  ? 511 SER C O     1 
ATOM   12164 C CB    . SER C 1 511 ? -15.153 -7.778  -59.514  1.00 47.66  ? 511 SER C CB    1 
ATOM   12165 O OG    . SER C 1 511 ? -16.392 -7.089  -59.420  1.00 46.81  ? 511 SER C OG    1 
ATOM   12166 N N     . GLY C 1 512 ? -13.705 -10.869 -60.824  1.00 45.25  ? 512 GLY C N     1 
ATOM   12167 C CA    . GLY C 1 512 ? -12.423 -11.543 -60.940  1.00 48.04  ? 512 GLY C CA    1 
ATOM   12168 C C     . GLY C 1 512 ? -11.810 -11.926 -59.596  1.00 47.32  ? 512 GLY C C     1 
ATOM   12169 O O     . GLY C 1 512 ? -10.590 -12.056 -59.502  1.00 39.64  ? 512 GLY C O     1 
ATOM   12170 N N     . ILE C 1 513 ? -12.674 -12.151 -58.588  1.00 51.65  ? 513 ILE C N     1 
ATOM   12171 C CA    . ILE C 1 513 ? -12.246 -12.460 -57.227  1.00 50.34  ? 513 ILE C CA    1 
ATOM   12172 C C     . ILE C 1 513 ? -12.742 -13.855 -56.843  1.00 48.98  ? 513 ILE C C     1 
ATOM   12173 O O     . ILE C 1 513 ? -13.937 -14.128 -56.893  1.00 50.67  ? 513 ILE C O     1 
ATOM   12174 C CB    . ILE C 1 513 ? -12.776 -11.371 -56.271  1.00 54.22  ? 513 ILE C CB    1 
ATOM   12175 C CG1   . ILE C 1 513 ? -12.297 -9.978  -56.699  1.00 57.01  ? 513 ILE C CG1   1 
ATOM   12176 C CG2   . ILE C 1 513 ? -12.425 -11.679 -54.823  1.00 47.92  ? 513 ILE C CG2   1 
ATOM   12177 C CD1   . ILE C 1 513 ? -13.054 -8.829  -56.064  1.00 52.86  ? 513 ILE C CD1   1 
ATOM   12178 N N     . TRP C 1 514 ? -11.832 -14.738 -56.412  1.00 53.18  ? 514 TRP C N     1 
ATOM   12179 C CA    . TRP C 1 514 ? -12.153 -16.157 -56.344  1.00 54.61  ? 514 TRP C CA    1 
ATOM   12180 C C     . TRP C 1 514 ? -12.082 -16.699 -54.908  1.00 68.98  ? 514 TRP C C     1 
ATOM   12181 O O     . TRP C 1 514 ? -13.026 -17.403 -54.437  1.00 76.57  ? 514 TRP C O     1 
ATOM   12182 C CB    . TRP C 1 514 ? -11.245 -16.900 -57.340  1.00 56.11  ? 514 TRP C CB    1 
ATOM   12183 C CG    . TRP C 1 514 ? -11.678 -16.672 -58.755  1.00 50.25  ? 514 TRP C CG    1 
ATOM   12184 C CD1   . TRP C 1 514 ? -11.239 -15.714 -59.628  1.00 55.48  ? 514 TRP C CD1   1 
ATOM   12185 C CD2   . TRP C 1 514 ? -12.693 -17.409 -59.450  1.00 49.94  ? 514 TRP C CD2   1 
ATOM   12186 N NE1   . TRP C 1 514 ? -11.920 -15.801 -60.818  1.00 51.65  ? 514 TRP C NE1   1 
ATOM   12187 C CE2   . TRP C 1 514 ? -12.812 -16.836 -60.736  1.00 49.97  ? 514 TRP C CE2   1 
ATOM   12188 C CE3   . TRP C 1 514 ? -13.483 -18.515 -59.112  1.00 51.22  ? 514 TRP C CE3   1 
ATOM   12189 C CZ2   . TRP C 1 514 ? -13.716 -17.315 -61.677  1.00 51.74  ? 514 TRP C CZ2   1 
ATOM   12190 C CZ3   . TRP C 1 514 ? -14.377 -18.988 -60.043  1.00 57.57  ? 514 TRP C CZ3   1 
ATOM   12191 C CH2   . TRP C 1 514 ? -14.492 -18.388 -61.305  1.00 54.37  ? 514 TRP C CH2   1 
ATOM   12192 N N     . GLY C 1 515 ? -10.962 -16.370 -54.232  1.00 58.13  ? 515 GLY C N     1 
ATOM   12193 C CA    . GLY C 1 515 ? -10.730 -16.836 -52.873  1.00 63.57  ? 515 GLY C CA    1 
ATOM   12194 C C     . GLY C 1 515 ? -10.122 -18.233 -52.869  1.00 60.26  ? 515 GLY C C     1 
ATOM   12195 O O     . GLY C 1 515 ? -10.247 -18.935 -53.858  1.00 66.29  ? 515 GLY C O     1 
ATOM   12196 N N     . LYS C 1 516 ? -9.471  -18.628 -51.763  1.00 64.43  ? 516 LYS C N     1 
ATOM   12197 C CA    . LYS C 1 516 ? -8.342  -19.554 -51.833  1.00 67.78  ? 516 LYS C CA    1 
ATOM   12198 C C     . LYS C 1 516 ? -8.769  -20.931 -52.330  1.00 66.25  ? 516 LYS C C     1 
ATOM   12199 O O     . LYS C 1 516 ? -7.993  -21.595 -53.004  1.00 61.98  ? 516 LYS C O     1 
ATOM   12200 C CB    . LYS C 1 516 ? -7.571  -19.674 -50.509  1.00 69.35  ? 516 LYS C CB    1 
ATOM   12201 C CG    . LYS C 1 516 ? -8.376  -19.891 -49.236  1.00 75.94  ? 516 LYS C CG    1 
ATOM   12202 C CD    . LYS C 1 516 ? -7.461  -20.056 -48.014  1.00 94.77  ? 516 LYS C CD    1 
ATOM   12203 C CE    . LYS C 1 516 ? -8.046  -19.570 -46.699  1.00 97.55  ? 516 LYS C CE    1 
ATOM   12204 N NZ    . LYS C 1 516 ? -9.377  -20.166 -46.429  1.00 96.22  ? 516 LYS C NZ    1 
ATOM   12205 N N     . ASN C 1 517 ? -9.996  -21.341 -52.002  1.00 67.87  ? 517 ASN C N     1 
ATOM   12206 C CA    . ASN C 1 517 ? -10.505 -22.649 -52.372  1.00 67.53  ? 517 ASN C CA    1 
ATOM   12207 C C     . ASN C 1 517 ? -10.424 -22.906 -53.878  1.00 64.60  ? 517 ASN C C     1 
ATOM   12208 O O     . ASN C 1 517 ? -10.413 -24.071 -54.283  1.00 64.75  ? 517 ASN C O     1 
ATOM   12209 C CB    . ASN C 1 517 ? -11.956 -22.822 -51.912  1.00 67.04  ? 517 ASN C CB    1 
ATOM   12210 C CG    . ASN C 1 517 ? -12.066 -23.137 -50.440  1.00 69.72  ? 517 ASN C CG    1 
ATOM   12211 O OD1   . ASN C 1 517 ? -11.101 -23.575 -49.820  1.00 65.10  ? 517 ASN C OD1   1 
ATOM   12212 N ND2   . ASN C 1 517 ? -13.247 -22.938 -49.881  1.00 70.18  ? 517 ASN C ND2   1 
ATOM   12213 N N     . ARG C 1 518 ? -10.399 -21.837 -54.690  1.00 56.42  ? 518 ARG C N     1 
ATOM   12214 C CA    . ARG C 1 518 ? -10.727 -21.938 -56.100  1.00 54.88  ? 518 ARG C CA    1 
ATOM   12215 C C     . ARG C 1 518 ? -9.780  -21.183 -57.031  1.00 59.68  ? 518 ARG C C     1 
ATOM   12216 O O     . ARG C 1 518 ? -10.069 -21.137 -58.218  1.00 79.98  ? 518 ARG C O     1 
ATOM   12217 C CB    . ARG C 1 518 ? -12.111 -21.338 -56.363  1.00 55.59  ? 518 ARG C CB    1 
ATOM   12218 C CG    . ARG C 1 518 ? -13.285 -22.118 -55.794  1.00 57.89  ? 518 ARG C CG    1 
ATOM   12219 C CD    . ARG C 1 518 ? -14.604 -21.458 -56.171  1.00 65.33  ? 518 ARG C CD    1 
ATOM   12220 N NE    . ARG C 1 518 ? -15.751 -22.033 -55.480  1.00 73.89  ? 518 ARG C NE    1 
ATOM   12221 C CZ    . ARG C 1 518 ? -16.265 -23.234 -55.741  1.00 87.58  ? 518 ARG C CZ    1 
ATOM   12222 N NH1   . ARG C 1 518 ? -15.899 -23.899 -56.827  1.00 95.60  ? 518 ARG C NH1   1 
ATOM   12223 N NH2   . ARG C 1 518 ? -17.176 -23.751 -54.932  1.00 85.59  ? 518 ARG C NH2   1 
ATOM   12224 N N     . ARG C 1 519 ? -8.683  -20.573 -56.572  1.00 67.21  ? 519 ARG C N     1 
ATOM   12225 C CA    . ARG C 1 519 ? -7.865  -19.800 -57.504  1.00 80.23  ? 519 ARG C CA    1 
ATOM   12226 C C     . ARG C 1 519 ? -6.628  -20.603 -57.931  1.00 79.74  ? 519 ARG C C     1 
ATOM   12227 O O     . ARG C 1 519 ? -6.084  -21.307 -57.054  1.00 80.57  ? 519 ARG C O     1 
ATOM   12228 C CB    . ARG C 1 519 ? -7.512  -18.414 -56.946  1.00 82.48  ? 519 ARG C CB    1 
ATOM   12229 C CG    . ARG C 1 519 ? -6.647  -18.387 -55.696  1.00 81.68  ? 519 ARG C CG    1 
ATOM   12230 C CD    . ARG C 1 519 ? -6.298  -16.962 -55.262  1.00 82.61  ? 519 ARG C CD    1 
ATOM   12231 N NE    . ARG C 1 519 ? -5.591  -16.967 -53.977  1.00 85.33  ? 519 ARG C NE    1 
ATOM   12232 C CZ    . ARG C 1 519 ? -6.136  -16.704 -52.786  1.00 88.78  ? 519 ARG C CZ    1 
ATOM   12233 N NH1   . ARG C 1 519 ? -7.335  -16.149 -52.681  1.00 88.15  ? 519 ARG C NH1   1 
ATOM   12234 N NH2   . ARG C 1 519 ? -5.460  -16.984 -51.686  1.00 91.83  ? 519 ARG C NH2   1 
HETATM 12235 P PA    . FAD D 2 .   ? -31.433 -18.715 -6.962   1.00 67.01  ? 601 FAD A PA    1 
HETATM 12236 O O1A   . FAD D 2 .   ? -31.115 -19.461 -8.228   1.00 54.28  ? 601 FAD A O1A   1 
HETATM 12237 O O2A   . FAD D 2 .   ? -31.049 -19.338 -5.662   1.00 66.62  ? 601 FAD A O2A   1 
HETATM 12238 O O5B   . FAD D 2 .   ? -30.834 -17.214 -6.974   1.00 63.57  ? 601 FAD A O5B   1 
HETATM 12239 C C5B   . FAD D 2 .   ? -30.827 -16.379 -8.163   1.00 64.16  ? 601 FAD A C5B   1 
HETATM 12240 C C4B   . FAD D 2 .   ? -29.522 -15.616 -8.198   1.00 62.17  ? 601 FAD A C4B   1 
HETATM 12241 O O4B   . FAD D 2 .   ? -29.426 -14.760 -7.025   1.00 56.24  ? 601 FAD A O4B   1 
HETATM 12242 C C3B   . FAD D 2 .   ? -28.247 -16.477 -8.176   1.00 62.75  ? 601 FAD A C3B   1 
HETATM 12243 O O3B   . FAD D 2 .   ? -27.715 -16.741 -9.464   1.00 65.49  ? 601 FAD A O3B   1 
HETATM 12244 C C2B   . FAD D 2 .   ? -27.216 -15.608 -7.449   1.00 61.22  ? 601 FAD A C2B   1 
HETATM 12245 O O2B   . FAD D 2 .   ? -26.430 -14.811 -8.317   1.00 70.43  ? 601 FAD A O2B   1 
HETATM 12246 C C1B   . FAD D 2 .   ? -28.100 -14.805 -6.502   1.00 60.36  ? 601 FAD A C1B   1 
HETATM 12247 N N9A   . FAD D 2 .   ? -28.160 -15.398 -5.148   1.00 58.03  ? 601 FAD A N9A   1 
HETATM 12248 C C8A   . FAD D 2 .   ? -28.996 -16.413 -4.698   1.00 57.21  ? 601 FAD A C8A   1 
HETATM 12249 N N7A   . FAD D 2 .   ? -28.839 -16.681 -3.428   1.00 45.83  ? 601 FAD A N7A   1 
HETATM 12250 C C5A   . FAD D 2 .   ? -27.858 -15.792 -3.018   1.00 56.09  ? 601 FAD A C5A   1 
HETATM 12251 C C6A   . FAD D 2 .   ? -27.267 -15.573 -1.760   1.00 52.79  ? 601 FAD A C6A   1 
HETATM 12252 N N6A   . FAD D 2 .   ? -27.626 -16.266 -0.679   1.00 49.14  ? 601 FAD A N6A   1 
HETATM 12253 N N1A   . FAD D 2 .   ? -26.320 -14.600 -1.679   1.00 46.21  ? 601 FAD A N1A   1 
HETATM 12254 C C2A   . FAD D 2 .   ? -25.999 -13.927 -2.798   1.00 59.04  ? 601 FAD A C2A   1 
HETATM 12255 N N3A   . FAD D 2 .   ? -26.503 -14.032 -4.030   1.00 61.96  ? 601 FAD A N3A   1 
HETATM 12256 C C4A   . FAD D 2 .   ? -27.438 -14.996 -4.067   1.00 53.23  ? 601 FAD A C4A   1 
HETATM 12257 N N1    . FAD D 2 .   ? -39.259 -15.250 -11.581  1.00 56.53  ? 601 FAD A N1    1 
HETATM 12258 C C2    . FAD D 2 .   ? -40.102 -14.394 -10.950  1.00 60.17  ? 601 FAD A C2    1 
HETATM 12259 O O2    . FAD D 2 .   ? -39.673 -13.592 -10.117  1.00 49.60  ? 601 FAD A O2    1 
HETATM 12260 N N3    . FAD D 2 .   ? -41.476 -14.393 -11.201  1.00 65.21  ? 601 FAD A N3    1 
HETATM 12261 C C4    . FAD D 2 .   ? -42.048 -15.240 -12.127  1.00 61.98  ? 601 FAD A C4    1 
HETATM 12262 O O4    . FAD D 2 .   ? -43.261 -15.230 -12.318  1.00 56.55  ? 601 FAD A O4    1 
HETATM 12263 C C4X   . FAD D 2 .   ? -41.186 -16.114 -12.820  1.00 71.03  ? 601 FAD A C4X   1 
HETATM 12264 N N5    . FAD D 2 .   ? -41.712 -16.901 -13.723  1.00 78.42  ? 601 FAD A N5    1 
HETATM 12265 C C5X   . FAD D 2 .   ? -40.869 -17.735 -14.406  1.00 78.70  ? 601 FAD A C5X   1 
HETATM 12266 C C6    . FAD D 2 .   ? -41.429 -18.580 -15.379  1.00 78.18  ? 601 FAD A C6    1 
HETATM 12267 C C7    . FAD D 2 .   ? -40.666 -19.460 -16.103  1.00 75.45  ? 601 FAD A C7    1 
HETATM 12268 C C7M   . FAD D 2 .   ? -41.338 -20.355 -17.114  1.00 80.37  ? 601 FAD A C7M   1 
HETATM 12269 C C8    . FAD D 2 .   ? -39.261 -19.508 -15.883  1.00 74.64  ? 601 FAD A C8    1 
HETATM 12270 C C8M   . FAD D 2 .   ? -38.368 -20.376 -16.753  1.00 75.33  ? 601 FAD A C8M   1 
HETATM 12271 C C9    . FAD D 2 .   ? -38.695 -18.650 -14.945  1.00 80.80  ? 601 FAD A C9    1 
HETATM 12272 C C9A   . FAD D 2 .   ? -39.481 -17.766 -14.174  1.00 76.61  ? 601 FAD A C9A   1 
HETATM 12273 N N10   . FAD D 2 .   ? -38.957 -16.902 -13.205  1.00 68.72  ? 601 FAD A N10   1 
HETATM 12274 C C10   . FAD D 2 .   ? -39.780 -16.062 -12.485  1.00 69.04  ? 601 FAD A C10   1 
HETATM 12275 C "C1'" . FAD D 2 .   ? -37.523 -16.940 -12.875  1.00 70.06  ? 601 FAD A "C1'" 1 
HETATM 12276 C "C2'" . FAD D 2 .   ? -37.309 -18.033 -11.803  1.00 75.26  ? 601 FAD A "C2'" 1 
HETATM 12277 O "O2'" . FAD D 2 .   ? -38.188 -19.144 -12.032  1.00 79.25  ? 601 FAD A "O2'" 1 
HETATM 12278 C "C3'" . FAD D 2 .   ? -37.579 -17.603 -10.353  1.00 64.89  ? 601 FAD A "C3'" 1 
HETATM 12279 O "O3'" . FAD D 2 .   ? -37.238 -16.236 -10.192  1.00 63.93  ? 601 FAD A "O3'" 1 
HETATM 12280 C "C4'" . FAD D 2 .   ? -36.810 -18.470 -9.347   1.00 56.55  ? 601 FAD A "C4'" 1 
HETATM 12281 O "O4'" . FAD D 2 .   ? -37.535 -18.546 -8.121   1.00 53.29  ? 601 FAD A "O4'" 1 
HETATM 12282 C "C5'" . FAD D 2 .   ? -35.401 -17.976 -9.088   1.00 54.44  ? 601 FAD A "C5'" 1 
HETATM 12283 O "O5'" . FAD D 2 .   ? -34.511 -19.095 -8.739   1.00 52.43  ? 601 FAD A "O5'" 1 
HETATM 12284 P P     . FAD D 2 .   ? -34.210 -19.408 -7.195   1.00 55.51  ? 601 FAD A P     1 
HETATM 12285 O O1P   . FAD D 2 .   ? -35.468 -18.942 -6.513   1.00 48.63  ? 601 FAD A O1P   1 
HETATM 12286 O O2P   . FAD D 2 .   ? -33.604 -20.775 -7.018   1.00 46.42  ? 601 FAD A O2P   1 
HETATM 12287 O O3P   . FAD D 2 .   ? -33.005 -18.407 -6.905   1.00 62.02  ? 601 FAD A O3P   1 
HETATM 12288 P PA    . FAD E 2 .   ? -2.229  14.220  -39.472  1.00 65.25  ? 601 FAD B PA    1 
HETATM 12289 O O1A   . FAD E 2 .   ? -1.943  14.434  -38.016  1.00 70.47  ? 601 FAD B O1A   1 
HETATM 12290 O O2A   . FAD E 2 .   ? -1.058  14.150  -40.401  1.00 71.18  ? 601 FAD B O2A   1 
HETATM 12291 O O5B   . FAD E 2 .   ? -3.135  12.898  -39.633  1.00 73.99  ? 601 FAD B O5B   1 
HETATM 12292 C C5B   . FAD E 2 .   ? -4.334  12.686  -38.815  1.00 74.78  ? 601 FAD B C5B   1 
HETATM 12293 C C4B   . FAD E 2 .   ? -4.477  11.216  -38.502  1.00 71.16  ? 601 FAD B C4B   1 
HETATM 12294 O O4B   . FAD E 2 .   ? -4.856  10.511  -39.714  1.00 74.85  ? 601 FAD B O4B   1 
HETATM 12295 C C3B   . FAD E 2 .   ? -3.209  10.495  -38.014  1.00 70.56  ? 601 FAD B C3B   1 
HETATM 12296 O O3B   . FAD E 2 .   ? -3.044  10.520  -36.604  1.00 74.53  ? 601 FAD B O3B   1 
HETATM 12297 C C2B   . FAD E 2 .   ? -3.429  9.056   -38.491  1.00 68.07  ? 601 FAD B C2B   1 
HETATM 12298 O O2B   . FAD E 2 .   ? -4.244  8.229   -37.687  1.00 65.37  ? 601 FAD B O2B   1 
HETATM 12299 C C1B   . FAD E 2 .   ? -4.104  9.314   -39.826  1.00 69.93  ? 601 FAD B C1B   1 
HETATM 12300 N N9A   . FAD E 2 .   ? -3.160  9.465   -40.925  1.00 67.47  ? 601 FAD B N9A   1 
HETATM 12301 C C8A   . FAD E 2 .   ? -2.618  10.639  -41.424  1.00 66.87  ? 601 FAD B C8A   1 
HETATM 12302 N N7A   . FAD E 2 .   ? -1.818  10.436  -42.443  1.00 59.39  ? 601 FAD B N7A   1 
HETATM 12303 C C5A   . FAD E 2 .   ? -1.862  9.059   -42.637  1.00 65.10  ? 601 FAD B C5A   1 
HETATM 12304 C C6A   . FAD E 2 .   ? -1.268  8.232   -43.606  1.00 53.96  ? 601 FAD B C6A   1 
HETATM 12305 N N6A   . FAD E 2 .   ? -0.481  8.715   -44.563  1.00 49.48  ? 601 FAD B N6A   1 
HETATM 12306 N N1A   . FAD E 2 .   ? -1.540  6.901   -43.548  1.00 50.92  ? 601 FAD B N1A   1 
HETATM 12307 C C2A   . FAD E 2 .   ? -2.337  6.451   -42.564  1.00 58.58  ? 601 FAD B C2A   1 
HETATM 12308 N N3A   . FAD E 2 .   ? -2.963  7.134   -41.607  1.00 61.48  ? 601 FAD B N3A   1 
HETATM 12309 C C4A   . FAD E 2 .   ? -2.685  8.449   -41.709  1.00 66.67  ? 601 FAD B C4A   1 
HETATM 12310 N N1    . FAD E 2 .   ? -10.064 20.307  -38.936  1.00 67.03  ? 601 FAD B N1    1 
HETATM 12311 C C2    . FAD E 2 .   ? -10.815 20.475  -40.042  1.00 64.38  ? 601 FAD B C2    1 
HETATM 12312 O O2    . FAD E 2 .   ? -11.038 19.534  -40.806  1.00 66.16  ? 601 FAD B O2    1 
HETATM 12313 N N3    . FAD E 2 .   ? -11.340 21.674  -40.382  1.00 67.53  ? 601 FAD B N3    1 
HETATM 12314 C C4    . FAD E 2 .   ? -11.162 22.789  -39.609  1.00 67.08  ? 601 FAD B C4    1 
HETATM 12315 O O4    . FAD E 2 .   ? -11.676 23.851  -39.940  1.00 64.67  ? 601 FAD B O4    1 
HETATM 12316 C C4X   . FAD E 2 .   ? -10.396 22.652  -38.440  1.00 75.39  ? 601 FAD B C4X   1 
HETATM 12317 N N5    . FAD E 2 .   ? -10.223 23.703  -37.692  1.00 78.33  ? 601 FAD B N5    1 
HETATM 12318 C C5X   . FAD E 2 .   ? -9.473  23.549  -36.559  1.00 73.41  ? 601 FAD B C5X   1 
HETATM 12319 C C6    . FAD E 2 .   ? -9.291  24.687  -35.764  1.00 74.10  ? 601 FAD B C6    1 
HETATM 12320 C C7    . FAD E 2 .   ? -8.564  24.664  -34.607  1.00 65.23  ? 601 FAD B C7    1 
HETATM 12321 C C7M   . FAD E 2 .   ? -8.401  25.954  -33.841  1.00 65.83  ? 601 FAD B C7M   1 
HETATM 12322 C C8    . FAD E 2 .   ? -7.982  23.441  -34.180  1.00 67.31  ? 601 FAD B C8    1 
HETATM 12323 C C8M   . FAD E 2 .   ? -7.271  23.342  -32.839  1.00 73.14  ? 601 FAD B C8M   1 
HETATM 12324 C C9    . FAD E 2 .   ? -8.167  22.300  -34.959  1.00 73.33  ? 601 FAD B C9    1 
HETATM 12325 C C9A   . FAD E 2 .   ? -8.902  22.322  -36.167  1.00 76.69  ? 601 FAD B C9A   1 
HETATM 12326 N N10   . FAD E 2 .   ? -9.107  21.211  -37.008  1.00 72.22  ? 601 FAD B N10   1 
HETATM 12327 C C10   . FAD E 2 .   ? -9.866  21.344  -38.157  1.00 71.19  ? 601 FAD B C10   1 
HETATM 12328 C "C1'" . FAD E 2 .   ? -8.545  19.880  -36.694  1.00 65.87  ? 601 FAD B "C1'" 1 
HETATM 12329 C "C2'" . FAD E 2 .   ? -7.089  19.694  -37.205  1.00 69.96  ? 601 FAD B "C2'" 1 
HETATM 12330 O "O2'" . FAD E 2 .   ? -6.237  20.659  -36.607  1.00 73.43  ? 601 FAD B "O2'" 1 
HETATM 12331 C "C3'" . FAD E 2 .   ? -6.894  19.763  -38.733  1.00 73.05  ? 601 FAD B "C3'" 1 
HETATM 12332 O "O3'" . FAD E 2 .   ? -7.739  18.794  -39.367  1.00 73.11  ? 601 FAD B "O3'" 1 
HETATM 12333 C "C4'" . FAD E 2 .   ? -5.464  19.502  -39.232  1.00 59.97  ? 601 FAD B "C4'" 1 
HETATM 12334 O "O4'" . FAD E 2 .   ? -5.279  20.115  -40.502  1.00 55.95  ? 601 FAD B "O4'" 1 
HETATM 12335 C "C5'" . FAD E 2 .   ? -5.155  18.029  -39.385  1.00 64.95  ? 601 FAD B "C5'" 1 
HETATM 12336 O "O5'" . FAD E 2 .   ? -3.740  17.718  -39.144  1.00 68.31  ? 601 FAD B "O5'" 1 
HETATM 12337 P P     . FAD E 2 .   ? -2.864  16.954  -40.257  1.00 63.35  ? 601 FAD B P     1 
HETATM 12338 O O1P   . FAD E 2 .   ? -3.476  17.462  -41.523  1.00 75.69  ? 601 FAD B O1P   1 
HETATM 12339 O O2P   . FAD E 2 .   ? -1.404  17.167  -39.984  1.00 62.20  ? 601 FAD B O2P   1 
HETATM 12340 O O3P   . FAD E 2 .   ? -3.189  15.399  -40.013  1.00 56.62  ? 601 FAD B O3P   1 
HETATM 12341 P PA    . FAD F 2 .   ? -28.968 -6.794  -60.572  1.00 70.56  ? 601 FAD C PA    1 
HETATM 12342 O O1A   . FAD F 2 .   ? -29.088 -7.744  -61.714  1.00 94.72  ? 601 FAD C O1A   1 
HETATM 12343 O O2A   . FAD F 2 .   ? -29.978 -6.967  -59.497  1.00 68.57  ? 601 FAD C O2A   1 
HETATM 12344 O O5B   . FAD F 2 .   ? -27.477 -6.886  -59.958  1.00 72.19  ? 601 FAD C O5B   1 
HETATM 12345 C C5B   . FAD F 2 .   ? -26.290 -6.784  -60.797  1.00 71.30  ? 601 FAD C C5B   1 
HETATM 12346 C C4B   . FAD F 2 .   ? -25.100 -7.372  -60.073  1.00 70.80  ? 601 FAD C C4B   1 
HETATM 12347 O O4B   . FAD F 2 .   ? -24.921 -6.659  -58.826  1.00 70.14  ? 601 FAD C O4B   1 
HETATM 12348 C C3B   . FAD F 2 .   ? -25.192 -8.855  -59.673  1.00 77.29  ? 601 FAD C C3B   1 
HETATM 12349 O O3B   . FAD F 2 .   ? -24.634 -9.730  -60.649  1.00 73.44  ? 601 FAD C O3B   1 
HETATM 12350 C C2B   . FAD F 2 .   ? -24.362 -8.936  -58.382  1.00 73.96  ? 601 FAD C C2B   1 
HETATM 12351 O O2B   . FAD F 2 .   ? -22.986 -9.223  -58.595  1.00 62.66  ? 601 FAD C O2B   1 
HETATM 12352 C C1B   . FAD F 2 .   ? -24.582 -7.550  -57.777  1.00 67.38  ? 601 FAD C C1B   1 
HETATM 12353 N N9A   . FAD F 2 .   ? -25.624 -7.447  -56.762  1.00 60.32  ? 601 FAD C N9A   1 
HETATM 12354 C C8A   . FAD F 2 .   ? -26.950 -7.042  -56.928  1.00 61.59  ? 601 FAD C C8A   1 
HETATM 12355 N N7A   . FAD F 2 .   ? -27.623 -7.001  -55.798  1.00 51.16  ? 601 FAD C N7A   1 
HETATM 12356 C C5A   . FAD F 2 .   ? -26.688 -7.384  -54.837  1.00 63.42  ? 601 FAD C C5A   1 
HETATM 12357 C C6A   . FAD F 2 .   ? -26.771 -7.506  -53.432  1.00 58.57  ? 601 FAD C C6A   1 
HETATM 12358 N N6A   . FAD F 2 .   ? -27.900 -7.312  -52.751  1.00 52.56  ? 601 FAD C N6A   1 
HETATM 12359 N N1A   . FAD F 2 .   ? -25.643 -7.864  -52.767  1.00 54.30  ? 601 FAD C N1A   1 
HETATM 12360 C C2A   . FAD F 2 .   ? -24.531 -8.095  -53.478  1.00 58.98  ? 601 FAD C C2A   1 
HETATM 12361 N N3A   . FAD F 2 .   ? -24.336 -8.012  -54.796  1.00 60.22  ? 601 FAD C N3A   1 
HETATM 12362 C C4A   . FAD F 2 .   ? -25.461 -7.648  -55.421  1.00 56.05  ? 601 FAD C C4A   1 
HETATM 12363 N N1    . FAD F 2 .   ? -27.138 0.353   -66.875  1.00 83.64  ? 601 FAD C N1    1 
HETATM 12364 C C2    . FAD F 2 .   ? -26.954 1.579   -66.330  1.00 80.30  ? 601 FAD C C2    1 
HETATM 12365 O O2    . FAD F 2 .   ? -26.410 1.705   -65.244  1.00 84.96  ? 601 FAD C O2    1 
HETATM 12366 N N3    . FAD F 2 .   ? -27.357 2.724   -66.928  1.00 84.14  ? 601 FAD C N3    1 
HETATM 12367 C C4    . FAD F 2 .   ? -27.999 2.723   -68.138  1.00 86.56  ? 601 FAD C C4    1 
HETATM 12368 O O4    . FAD F 2 .   ? -28.351 3.798   -68.624  1.00 76.92  ? 601 FAD C O4    1 
HETATM 12369 C C4X   . FAD F 2 .   ? -28.247 1.439   -68.746  1.00 97.26  ? 601 FAD C C4X   1 
HETATM 12370 N N5    . FAD F 2 .   ? -28.866 1.384   -69.903  1.00 113.06 ? 601 FAD C N5    1 
HETATM 12371 C C5X   . FAD F 2 .   ? -29.064 0.149   -70.464  1.00 103.38 ? 601 FAD C C5X   1 
HETATM 12372 C C6    . FAD F 2 .   ? -29.709 0.084   -71.709  1.00 97.05  ? 601 FAD C C6    1 
HETATM 12373 C C7    . FAD F 2 .   ? -29.945 -1.112  -72.339  1.00 96.92  ? 601 FAD C C7    1 
HETATM 12374 C C7M   . FAD F 2 .   ? -30.641 -1.113  -73.676  1.00 103.61 ? 601 FAD C C7M   1 
HETATM 12375 C C8    . FAD F 2 .   ? -29.531 -2.319  -71.717  1.00 99.81  ? 601 FAD C C8    1 
HETATM 12376 C C8M   . FAD F 2 .   ? -29.682 -3.647  -72.422  1.00 113.50 ? 601 FAD C C8M   1 
HETATM 12377 C C9    . FAD F 2 .   ? -28.873 -2.268  -70.508  1.00 100.08 ? 601 FAD C C9    1 
HETATM 12378 C C9A   . FAD F 2 .   ? -28.635 -1.045  -69.852  1.00 107.42 ? 601 FAD C C9A   1 
HETATM 12379 N N10   . FAD F 2 .   ? -27.966 -0.947  -68.632  1.00 102.07 ? 601 FAD C N10   1 
HETATM 12380 C C10   . FAD F 2 .   ? -27.769 0.282   -68.027  1.00 96.63  ? 601 FAD C C10   1 
HETATM 12381 C "C1'" . FAD F 2 .   ? -27.571 -2.173  -67.921  1.00 99.54  ? 601 FAD C "C1'" 1 
HETATM 12382 C "C2'" . FAD F 2 .   ? -28.786 -2.710  -67.128  1.00 99.91  ? 601 FAD C "C2'" 1 
HETATM 12383 O "O2'" . FAD F 2 .   ? -30.000 -2.782  -67.931  1.00 87.04  ? 601 FAD C "O2'" 1 
HETATM 12384 C "C3'" . FAD F 2 .   ? -29.088 -1.839  -65.904  1.00 81.80  ? 601 FAD C "C3'" 1 
HETATM 12385 O "O3'" . FAD F 2 .   ? -27.885 -1.526  -65.243  1.00 74.92  ? 601 FAD C "O3'" 1 
HETATM 12386 C "C4'" . FAD F 2 .   ? -30.046 -2.478  -64.894  1.00 82.43  ? 601 FAD C "C4'" 1 
HETATM 12387 O "O4'" . FAD F 2 .   ? -30.930 -1.465  -64.405  1.00 98.69  ? 601 FAD C "O4'" 1 
HETATM 12388 C "C5'" . FAD F 2 .   ? -29.338 -3.160  -63.740  1.00 79.27  ? 601 FAD C "C5'" 1 
HETATM 12389 O "O5'" . FAD F 2 .   ? -29.943 -4.456  -63.401  1.00 69.39  ? 601 FAD C "O5'" 1 
HETATM 12390 P P     . FAD F 2 .   ? -30.421 -4.778  -61.896  1.00 70.51  ? 601 FAD C P     1 
HETATM 12391 O O1P   . FAD F 2 .   ? -30.821 -3.480  -61.274  1.00 69.13  ? 601 FAD C O1P   1 
HETATM 12392 O O2P   . FAD F 2 .   ? -31.422 -5.893  -61.964  1.00 61.23  ? 601 FAD C O2P   1 
HETATM 12393 O O3P   . FAD F 2 .   ? -29.095 -5.311  -61.161  1.00 67.68  ? 601 FAD C O3P   1 
HETATM 12394 O O     . HOH G 3 .   ? -35.693 -8.046  -38.095  1.00 49.25  ? 701 HOH A O     1 
HETATM 12395 O O     . HOH G 3 .   ? -32.494 -10.014 -19.647  1.00 45.46  ? 702 HOH A O     1 
HETATM 12396 O O     . HOH G 3 .   ? -50.506 -5.976  4.828    1.00 32.57  ? 703 HOH A O     1 
HETATM 12397 O O     . HOH G 3 .   ? -23.305 6.154   -22.687  1.00 34.29  ? 704 HOH A O     1 
HETATM 12398 O O     . HOH G 3 .   ? -49.284 -12.430 -1.054   1.00 44.62  ? 705 HOH A O     1 
HETATM 12399 O O     . HOH G 3 .   ? -40.384 -19.935 -11.404  1.00 51.67  ? 706 HOH A O     1 
HETATM 12400 O O     . HOH G 3 .   ? -36.204 2.521   -18.836  1.00 36.09  ? 707 HOH A O     1 
HETATM 12401 O O     . HOH G 3 .   ? -62.994 -13.183 -24.880  1.00 48.53  ? 708 HOH A O     1 
HETATM 12402 O O     . HOH G 3 .   ? -34.871 -4.293  4.417    1.00 43.64  ? 709 HOH A O     1 
HETATM 12403 O O     . HOH G 3 .   ? -63.127 -20.226 -20.679  1.00 36.59  ? 710 HOH A O     1 
HETATM 12404 O O     . HOH G 3 .   ? -26.121 -26.444 1.205    1.00 43.06  ? 711 HOH A O     1 
HETATM 12405 O O     . HOH G 3 .   ? -33.119 4.648   10.742   1.00 32.12  ? 712 HOH A O     1 
HETATM 12406 O O     . HOH G 3 .   ? -54.135 -21.321 -0.192   1.00 45.90  ? 713 HOH A O     1 
HETATM 12407 O O     . HOH G 3 .   ? -48.758 -13.510 -28.742  1.00 32.91  ? 714 HOH A O     1 
HETATM 12408 O O     . HOH G 3 .   ? -33.660 -4.424  6.671    1.00 33.07  ? 715 HOH A O     1 
HETATM 12409 O O     . HOH G 3 .   ? -56.324 -12.356 8.217    1.00 45.56  ? 716 HOH A O     1 
HETATM 12410 O O     . HOH G 3 .   ? -47.850 -14.553 -6.599   1.00 51.05  ? 717 HOH A O     1 
HETATM 12411 O O     . HOH G 3 .   ? -50.286 -18.206 -0.317   1.00 39.94  ? 718 HOH A O     1 
HETATM 12412 O O     . HOH G 3 .   ? -41.589 -13.403 -28.037  1.00 40.37  ? 719 HOH A O     1 
HETATM 12413 O O     . HOH G 3 .   ? -28.548 0.557   -27.623  1.00 46.33  ? 720 HOH A O     1 
HETATM 12414 O O     . HOH G 3 .   ? -40.954 -1.599  -21.001  1.00 32.78  ? 721 HOH A O     1 
HETATM 12415 O O     . HOH G 3 .   ? -29.707 -10.466 16.244   1.00 36.06  ? 722 HOH A O     1 
HETATM 12416 O O     . HOH G 3 .   ? -35.956 -10.436 -17.359  1.00 46.07  ? 723 HOH A O     1 
HETATM 12417 O O     . HOH G 3 .   ? -22.023 2.242   -15.018  1.00 37.54  ? 724 HOH A O     1 
HETATM 12418 O O     . HOH G 3 .   ? -42.058 -17.322 -28.463  1.00 38.11  ? 725 HOH A O     1 
HETATM 12419 O O     . HOH G 3 .   ? -24.984 -7.045  12.860   1.00 34.57  ? 726 HOH A O     1 
HETATM 12420 O O     . HOH G 3 .   ? -47.901 -25.262 -24.921  1.00 38.98  ? 727 HOH A O     1 
HETATM 12421 O O     . HOH G 3 .   ? -61.400 -4.921  -27.503  1.00 55.53  ? 728 HOH A O     1 
HETATM 12422 O O     . HOH G 3 .   ? -37.341 -19.972 -35.294  1.00 51.74  ? 729 HOH A O     1 
HETATM 12423 O O     . HOH G 3 .   ? -53.618 -12.765 -18.941  1.00 32.77  ? 730 HOH A O     1 
HETATM 12424 O O     . HOH G 3 .   ? -21.697 0.367   -16.789  1.00 50.97  ? 731 HOH A O     1 
HETATM 12425 O O     . HOH G 3 .   ? -39.247 -6.415  -24.299  1.00 34.02  ? 732 HOH A O     1 
HETATM 12426 O O     . HOH G 3 .   ? -42.968 -1.915  9.618    1.00 42.78  ? 733 HOH A O     1 
HETATM 12427 O O     . HOH G 3 .   ? -53.211 -18.572 -0.409   1.00 36.16  ? 734 HOH A O     1 
HETATM 12428 O O     . HOH G 3 .   ? -61.207 -1.999  -29.905  1.00 36.36  ? 735 HOH A O     1 
HETATM 12429 O O     . HOH G 3 .   ? -47.437 -12.493 1.182    1.00 35.06  ? 736 HOH A O     1 
HETATM 12430 O O     . HOH G 3 .   ? -19.395 -4.677  -16.601  1.00 48.04  ? 737 HOH A O     1 
HETATM 12431 O O     . HOH G 3 .   ? -33.980 -13.628 -19.343  1.00 71.13  ? 738 HOH A O     1 
HETATM 12432 O O     . HOH G 3 .   ? -44.140 -14.656 0.060    1.00 45.80  ? 739 HOH A O     1 
HETATM 12433 O O     . HOH G 3 .   ? -30.944 2.125   7.658    1.00 38.41  ? 740 HOH A O     1 
HETATM 12434 O O     . HOH G 3 .   ? -34.262 -5.128  10.532   1.00 36.16  ? 741 HOH A O     1 
HETATM 12435 O O     . HOH G 3 .   ? -58.531 4.726   -16.072  1.00 50.52  ? 742 HOH A O     1 
HETATM 12436 O O     . HOH G 3 .   ? -39.294 -14.010 -2.496   1.00 26.54  ? 743 HOH A O     1 
HETATM 12437 O O     . HOH G 3 .   ? -29.881 -14.542 -37.261  1.00 57.59  ? 744 HOH A O     1 
HETATM 12438 O O     . HOH G 3 .   ? -26.885 0.457   9.203    1.00 38.82  ? 745 HOH A O     1 
HETATM 12439 O O     . HOH G 3 .   ? -65.125 -18.402 -21.325  1.00 43.16  ? 746 HOH A O     1 
HETATM 12440 O O     . HOH G 3 .   ? -45.178 -5.600  -3.339   1.00 36.91  ? 747 HOH A O     1 
HETATM 12441 O O     . HOH G 3 .   ? -58.294 -23.583 -22.556  1.00 35.94  ? 748 HOH A O     1 
HETATM 12442 O O     . HOH G 3 .   ? -22.322 -26.090 11.645   1.00 40.74  ? 749 HOH A O     1 
HETATM 12443 O O     . HOH G 3 .   ? -35.414 -19.113 0.934    1.00 45.18  ? 750 HOH A O     1 
HETATM 12444 O O     . HOH G 3 .   ? -37.545 5.260   -20.547  1.00 47.77  ? 751 HOH A O     1 
HETATM 12445 O O     . HOH G 3 .   ? -13.279 -13.694 8.656    1.00 49.52  ? 752 HOH A O     1 
HETATM 12446 O O     . HOH G 3 .   ? -45.427 5.714   -15.664  1.00 43.69  ? 753 HOH A O     1 
HETATM 12447 O O     . HOH G 3 .   ? -29.103 -0.000  -0.000   0.50 56.09  ? 754 HOH A O     1 
HETATM 12448 O O     . HOH G 3 .   ? -48.213 -8.315  -7.996   1.00 26.98  ? 755 HOH A O     1 
HETATM 12449 O O     . HOH G 3 .   ? -23.366 5.315   -14.630  1.00 38.48  ? 756 HOH A O     1 
HETATM 12450 O O     . HOH G 3 .   ? -62.051 -14.906 -33.216  1.00 39.02  ? 757 HOH A O     1 
HETATM 12451 O O     . HOH G 3 .   ? -16.685 8.012   -14.446  1.00 34.75  ? 758 HOH A O     1 
HETATM 12452 O O     . HOH G 3 .   ? -28.773 -19.458 8.589    1.00 34.15  ? 759 HOH A O     1 
HETATM 12453 O O     . HOH G 3 .   ? -46.666 -14.598 -32.929  1.00 48.86  ? 760 HOH A O     1 
HETATM 12454 O O     . HOH G 3 .   ? -29.664 -1.835  6.965    1.00 36.52  ? 761 HOH A O     1 
HETATM 12455 O O     . HOH G 3 .   ? -38.217 -7.557  -5.990   1.00 30.72  ? 762 HOH A O     1 
HETATM 12456 O O     . HOH G 3 .   ? -29.080 -1.364  9.385    1.00 41.04  ? 763 HOH A O     1 
HETATM 12457 O O     . HOH G 3 .   ? -27.296 -10.859 -4.693   1.00 38.80  ? 764 HOH A O     1 
HETATM 12458 O O     . HOH G 3 .   ? -43.203 -1.856  -5.275   1.00 38.87  ? 765 HOH A O     1 
HETATM 12459 O O     . HOH G 3 .   ? -30.782 -2.988  -20.734  1.00 39.86  ? 766 HOH A O     1 
HETATM 12460 O O     . HOH G 3 .   ? -44.529 -11.966 0.697    1.00 34.62  ? 767 HOH A O     1 
HETATM 12461 O O     . HOH G 3 .   ? -41.268 -10.164 16.702   1.00 42.91  ? 768 HOH A O     1 
HETATM 12462 O O     . HOH G 3 .   ? -17.742 6.931   -9.911   1.00 37.30  ? 769 HOH A O     1 
HETATM 12463 O O     . HOH G 3 .   ? -41.574 -1.764  1.255    1.00 44.10  ? 770 HOH A O     1 
HETATM 12464 O O     . HOH G 3 .   ? -39.682 -0.498  8.005    1.00 34.69  ? 771 HOH A O     1 
HETATM 12465 O O     . HOH G 3 .   ? -20.789 -10.777 -16.556  1.00 48.21  ? 772 HOH A O     1 
HETATM 12466 O O     . HOH G 3 .   ? -69.702 -0.836  -13.545  1.00 51.19  ? 773 HOH A O     1 
HETATM 12467 O O     . HOH G 3 .   ? -28.019 2.873   -22.773  1.00 34.23  ? 774 HOH A O     1 
HETATM 12468 O O     . HOH G 3 .   ? -19.051 -27.316 -16.212  1.00 50.67  ? 775 HOH A O     1 
HETATM 12469 O O     . HOH G 3 .   ? -32.158 -2.433  -23.126  1.00 34.31  ? 776 HOH A O     1 
HETATM 12470 O O     . HOH G 3 .   ? -31.589 -20.320 -18.248  1.00 60.72  ? 777 HOH A O     1 
HETATM 12471 O O     . HOH G 3 .   ? -41.380 -25.154 -27.707  1.00 44.16  ? 778 HOH A O     1 
HETATM 12472 O O     . HOH G 3 .   ? -43.277 -11.173 -1.196   1.00 33.58  ? 779 HOH A O     1 
HETATM 12473 O O     . HOH G 3 .   ? -41.882 -13.739 -2.124   1.00 40.58  ? 780 HOH A O     1 
HETATM 12474 O O     . HOH G 3 .   ? -69.375 -24.489 -19.249  1.00 45.18  ? 781 HOH A O     1 
HETATM 12475 O O     . HOH G 3 .   ? -28.860 -0.982  12.418   1.00 38.73  ? 782 HOH A O     1 
HETATM 12476 O O     . HOH G 3 .   ? -44.810 -12.687 18.826   1.00 42.42  ? 783 HOH A O     1 
HETATM 12477 O O     . HOH G 3 .   ? -38.829 -9.673  14.385   1.00 33.94  ? 784 HOH A O     1 
HETATM 12478 O O     . HOH G 3 .   ? -56.214 1.848   -28.585  1.00 43.29  ? 785 HOH A O     1 
HETATM 12479 O O     . HOH G 3 .   ? -24.590 -9.865  -2.593   1.00 52.02  ? 786 HOH A O     1 
HETATM 12480 O O     . HOH G 3 .   ? -48.343 -28.033 -9.626   1.00 39.49  ? 787 HOH A O     1 
HETATM 12481 O O     . HOH G 3 .   ? -22.914 -13.407 -4.061   1.00 51.17  ? 788 HOH A O     1 
HETATM 12482 O O     . HOH G 3 .   ? -44.436 2.471   -33.341  1.00 41.36  ? 789 HOH A O     1 
HETATM 12483 O O     . HOH G 3 .   ? -54.039 -15.028 -42.445  1.00 45.45  ? 790 HOH A O     1 
HETATM 12484 O O     . HOH G 3 .   ? -38.932 -21.621 -36.683  1.00 44.59  ? 791 HOH A O     1 
HETATM 12485 O O     . HOH G 3 .   ? -38.879 -24.947 -28.436  1.00 48.35  ? 792 HOH A O     1 
HETATM 12486 O O     . HOH G 3 .   ? -48.200 -15.180 16.538   1.00 50.66  ? 793 HOH A O     1 
HETATM 12487 O O     . HOH G 3 .   ? -13.597 -8.172  -17.337  1.00 46.95  ? 794 HOH A O     1 
HETATM 12488 O O     . HOH G 3 .   ? -64.707 -13.429 -1.859   1.00 42.68  ? 795 HOH A O     1 
HETATM 12489 O O     . HOH G 3 .   ? -62.459 -19.044 -36.670  1.00 16.39  ? 796 HOH A O     1 
HETATM 12490 O O     . HOH G 3 .   ? -56.330 -24.545 -15.252  1.00 44.33  ? 797 HOH A O     1 
HETATM 12491 O O     . HOH G 3 .   ? -15.861 -5.975  7.619    1.00 18.65  ? 798 HOH A O     1 
HETATM 12492 O O     . HOH G 3 .   ? -29.194 -11.454 19.722   1.00 37.70  ? 799 HOH A O     1 
HETATM 12493 O O     . HOH G 3 .   ? -66.518 -9.442  -4.903   1.00 57.30  ? 800 HOH A O     1 
HETATM 12494 O O     . HOH G 3 .   ? -29.664 -27.577 -8.231   1.00 51.00  ? 801 HOH A O     1 
HETATM 12495 O O     . HOH G 3 .   ? -31.683 0.892   -34.149  1.00 36.16  ? 802 HOH A O     1 
HETATM 12496 O O     . HOH G 3 .   ? -28.233 3.258   -26.871  1.00 47.93  ? 803 HOH A O     1 
HETATM 12497 O O     . HOH G 3 .   ? -58.719 -6.999  4.478    1.00 27.74  ? 804 HOH A O     1 
HETATM 12498 O O     . HOH G 3 .   ? -41.776 -0.104  -3.569   1.00 42.27  ? 805 HOH A O     1 
HETATM 12499 O O     . HOH G 3 .   ? -54.080 -24.639 -15.641  1.00 37.24  ? 806 HOH A O     1 
HETATM 12500 O O     . HOH G 3 .   ? -49.495 -3.502  0.285    1.00 43.55  ? 807 HOH A O     1 
HETATM 12501 O O     . HOH G 3 .   ? -49.100 0.126   -3.851   1.00 45.63  ? 808 HOH A O     1 
HETATM 12502 O O     . HOH G 3 .   ? -50.099 -13.401 -33.032  1.00 27.20  ? 809 HOH A O     1 
HETATM 12503 O O     . HOH G 3 .   ? -16.516 0.059   -15.250  1.00 41.06  ? 810 HOH A O     1 
HETATM 12504 O O     . HOH G 3 .   ? -32.259 -16.578 14.316   1.00 30.74  ? 811 HOH A O     1 
HETATM 12505 O O     . HOH G 3 .   ? -60.720 -18.167 -7.003   1.00 26.53  ? 812 HOH A O     1 
HETATM 12506 O O     . HOH G 3 .   ? -50.030 0.000   0.000    0.50 31.88  ? 813 HOH A O     1 
HETATM 12507 O O     . HOH H 3 .   ? -16.018 22.058  -60.005  1.00 44.92  ? 701 HOH B O     1 
HETATM 12508 O O     . HOH H 3 .   ? -35.665 37.051  -33.836  1.00 51.04  ? 702 HOH B O     1 
HETATM 12509 O O     . HOH H 3 .   ? -20.491 6.475   -21.120  1.00 40.86  ? 703 HOH B O     1 
HETATM 12510 O O     . HOH H 3 .   ? -15.728 9.912   -39.883  1.00 42.25  ? 704 HOH B O     1 
HETATM 12511 O O     . HOH H 3 .   ? -12.143 25.314  -52.809  1.00 47.33  ? 705 HOH B O     1 
HETATM 12512 O O     . HOH H 3 .   ? 9.414   11.732  -43.240  1.00 52.21  ? 706 HOH B O     1 
HETATM 12513 O O     . HOH H 3 .   ? -26.501 10.929  -35.330  1.00 34.21  ? 707 HOH B O     1 
HETATM 12514 O O     . HOH H 3 .   ? -7.406  17.700  -47.490  1.00 33.16  ? 708 HOH B O     1 
HETATM 12515 O O     . HOH H 3 .   ? -11.002 1.668   -54.785  1.00 49.91  ? 709 HOH B O     1 
HETATM 12516 O O     . HOH H 3 .   ? -29.704 18.599  -54.225  1.00 36.38  ? 710 HOH B O     1 
HETATM 12517 O O     . HOH H 3 .   ? 0.793   12.782  -25.179  1.00 62.63  ? 711 HOH B O     1 
HETATM 12518 O O     . HOH H 3 .   ? 5.229   8.859   -52.175  1.00 34.69  ? 712 HOH B O     1 
HETATM 12519 O O     . HOH H 3 .   ? -17.656 45.368  -38.295  1.00 42.94  ? 713 HOH B O     1 
HETATM 12520 O O     . HOH H 3 .   ? -10.146 6.250   -55.650  1.00 62.83  ? 714 HOH B O     1 
HETATM 12521 O O     . HOH H 3 .   ? -16.359 0.688   -61.555  1.00 43.70  ? 715 HOH B O     1 
HETATM 12522 O O     . HOH H 3 .   ? -18.565 8.789   -22.200  1.00 34.98  ? 716 HOH B O     1 
HETATM 12523 O O     . HOH H 3 .   ? -8.457  31.235  -53.572  1.00 48.55  ? 717 HOH B O     1 
HETATM 12524 O O     . HOH H 3 .   ? -22.131 19.202  -29.531  1.00 46.44  ? 718 HOH B O     1 
HETATM 12525 O O     . HOH H 3 .   ? -0.473  16.580  -48.114  1.00 59.47  ? 719 HOH B O     1 
HETATM 12526 O O     . HOH H 3 .   ? -9.455  -8.275  -24.430  1.00 58.21  ? 720 HOH B O     1 
HETATM 12527 O O     . HOH H 3 .   ? -19.575 -8.485  -37.956  1.00 39.34  ? 721 HOH B O     1 
HETATM 12528 O O     . HOH H 3 .   ? -21.265 31.779  -27.613  1.00 37.58  ? 722 HOH B O     1 
HETATM 12529 O O     . HOH H 3 .   ? -28.616 40.848  -35.875  1.00 38.51  ? 723 HOH B O     1 
HETATM 12530 O O     . HOH H 3 .   ? -25.565 17.441  -34.117  1.00 32.48  ? 724 HOH B O     1 
HETATM 12531 O O     . HOH H 3 .   ? -2.758  -1.323  -57.761  1.00 49.42  ? 725 HOH B O     1 
HETATM 12532 O O     . HOH H 3 .   ? -11.649 26.337  -47.154  1.00 46.79  ? 726 HOH B O     1 
HETATM 12533 O O     . HOH H 3 .   ? -36.336 30.403  -33.738  1.00 54.05  ? 727 HOH B O     1 
HETATM 12534 O O     . HOH H 3 .   ? -22.374 -2.402  -35.016  1.00 40.31  ? 728 HOH B O     1 
HETATM 12535 O O     . HOH H 3 .   ? -6.793  23.217  -39.263  1.00 70.29  ? 729 HOH B O     1 
HETATM 12536 O O     . HOH H 3 .   ? -8.236  3.523   -28.852  1.00 44.49  ? 730 HOH B O     1 
HETATM 12537 O O     . HOH H 3 .   ? -19.940 33.105  -38.132  1.00 43.54  ? 731 HOH B O     1 
HETATM 12538 O O     . HOH H 3 .   ? -8.746  6.244   -59.640  1.00 35.22  ? 732 HOH B O     1 
HETATM 12539 O O     . HOH H 3 .   ? -17.364 12.320  -12.304  1.00 40.06  ? 733 HOH B O     1 
HETATM 12540 O O     . HOH H 3 .   ? -32.620 37.938  -35.191  1.00 42.19  ? 734 HOH B O     1 
HETATM 12541 O O     . HOH H 3 .   ? -13.218 9.266   -51.481  1.00 37.50  ? 735 HOH B O     1 
HETATM 12542 O O     . HOH H 3 .   ? -14.591 46.156  -23.047  1.00 38.39  ? 736 HOH B O     1 
HETATM 12543 O O     . HOH H 3 .   ? -11.881 17.580  -30.366  1.00 47.37  ? 737 HOH B O     1 
HETATM 12544 O O     . HOH H 3 .   ? -13.966 14.759  -45.368  1.00 32.22  ? 738 HOH B O     1 
HETATM 12545 O O     . HOH H 3 .   ? -24.981 42.689  -36.029  1.00 40.40  ? 739 HOH B O     1 
HETATM 12546 O O     . HOH H 3 .   ? -13.530 29.181  -15.492  1.00 51.48  ? 740 HOH B O     1 
HETATM 12547 O O     . HOH H 3 .   ? -11.217 19.637  -50.656  1.00 39.97  ? 741 HOH B O     1 
HETATM 12548 O O     . HOH H 3 .   ? -25.633 45.254  -47.351  1.00 61.02  ? 742 HOH B O     1 
HETATM 12549 O O     . HOH H 3 .   ? -20.605 9.594   -30.381  1.00 33.64  ? 743 HOH B O     1 
HETATM 12550 O O     . HOH H 3 .   ? -33.916 33.785  -27.447  1.00 52.51  ? 744 HOH B O     1 
HETATM 12551 O O     . HOH H 3 .   ? -35.388 28.865  -47.006  1.00 51.55  ? 745 HOH B O     1 
HETATM 12552 O O     . HOH H 3 .   ? -25.030 15.045  -46.154  1.00 42.68  ? 746 HOH B O     1 
HETATM 12553 O O     . HOH H 3 .   ? -10.204 20.864  -53.058  1.00 39.91  ? 747 HOH B O     1 
HETATM 12554 O O     . HOH H 3 .   ? -29.813 12.458  -22.915  1.00 41.53  ? 748 HOH B O     1 
HETATM 12555 O O     . HOH H 3 .   ? -7.899  30.394  -22.897  1.00 53.84  ? 749 HOH B O     1 
HETATM 12556 O O     . HOH H 3 .   ? -7.554  28.918  -52.498  1.00 45.90  ? 750 HOH B O     1 
HETATM 12557 O O     . HOH H 3 .   ? -31.455 16.373  -42.427  1.00 46.89  ? 751 HOH B O     1 
HETATM 12558 O O     . HOH H 3 .   ? -19.351 12.135  -48.183  1.00 44.49  ? 752 HOH B O     1 
HETATM 12559 O O     . HOH H 3 .   ? -25.755 31.891  -28.882  1.00 50.11  ? 753 HOH B O     1 
HETATM 12560 O O     . HOH H 3 .   ? -24.253 47.794  -24.417  1.00 30.86  ? 754 HOH B O     1 
HETATM 12561 O O     . HOH H 3 .   ? -11.594 6.101   -25.393  1.00 45.95  ? 755 HOH B O     1 
HETATM 12562 O O     . HOH H 3 .   ? -22.331 10.767  -28.906  1.00 40.35  ? 756 HOH B O     1 
HETATM 12563 O O     . HOH H 3 .   ? -6.603  6.601   -41.799  1.00 39.97  ? 757 HOH B O     1 
HETATM 12564 O O     . HOH H 3 .   ? -8.699  19.811  -48.891  1.00 42.98  ? 758 HOH B O     1 
HETATM 12565 O O     . HOH H 3 .   ? -12.723 22.307  -32.152  1.00 58.70  ? 759 HOH B O     1 
HETATM 12566 O O     . HOH H 3 .   ? -24.256 39.921  -53.976  1.00 53.77  ? 760 HOH B O     1 
HETATM 12567 O O     . HOH H 3 .   ? 4.367   17.117  -35.618  1.00 48.12  ? 761 HOH B O     1 
HETATM 12568 O O     . HOH H 3 .   ? -11.017 23.294  -53.952  1.00 48.52  ? 762 HOH B O     1 
HETATM 12569 O O     . HOH H 3 .   ? -10.391 33.358  -39.381  1.00 51.07  ? 763 HOH B O     1 
HETATM 12570 O O     . HOH H 3 .   ? 0.000   7.466   -72.363  0.50 48.45  ? 764 HOH B O     1 
HETATM 12571 O O     . HOH H 3 .   ? -1.338  33.606  -41.179  1.00 47.74  ? 765 HOH B O     1 
HETATM 12572 O O     . HOH H 3 .   ? 7.263   19.922  -55.087  1.00 49.57  ? 766 HOH B O     1 
HETATM 12573 O O     . HOH H 3 .   ? -26.751 39.913  -16.614  1.00 27.03  ? 767 HOH B O     1 
HETATM 12574 O O     . HOH H 3 .   ? -18.175 29.850  -62.218  1.00 34.21  ? 768 HOH B O     1 
HETATM 12575 O O     . HOH H 3 .   ? -29.910 39.356  -26.391  1.00 42.24  ? 769 HOH B O     1 
HETATM 12576 O O     . HOH H 3 .   ? -27.378 5.533   -25.782  1.00 44.05  ? 770 HOH B O     1 
HETATM 12577 O O     . HOH H 3 .   ? -29.366 42.320  -19.633  1.00 39.63  ? 771 HOH B O     1 
HETATM 12578 O O     . HOH H 3 .   ? -7.104  37.832  -30.103  1.00 49.71  ? 772 HOH B O     1 
HETATM 12579 O O     . HOH H 3 .   ? 3.037   9.165   -60.089  1.00 45.03  ? 773 HOH B O     1 
HETATM 12580 O O     . HOH H 3 .   ? -23.720 20.038  -53.430  1.00 48.37  ? 774 HOH B O     1 
HETATM 12581 O O     . HOH H 3 .   ? -23.319 33.534  -24.170  1.00 11.44  ? 775 HOH B O     1 
HETATM 12582 O O     . HOH H 3 .   ? -14.051 39.308  -50.419  1.00 35.54  ? 776 HOH B O     1 
HETATM 12583 O O     . HOH I 3 .   ? -22.482 -9.739  -61.596  1.00 62.40  ? 701 HOH C O     1 
HETATM 12584 O O     . HOH I 3 .   ? -38.197 -13.654 -42.350  1.00 37.03  ? 702 HOH C O     1 
HETATM 12585 O O     . HOH I 3 .   ? -4.034  -21.326 -58.485  1.00 55.09  ? 703 HOH C O     1 
HETATM 12586 O O     . HOH I 3 .   ? -29.562 3.250   -58.624  1.00 33.97  ? 704 HOH C O     1 
HETATM 12587 O O     . HOH I 3 .   ? -31.926 6.411   -39.446  1.00 46.77  ? 705 HOH C O     1 
HETATM 12588 O O     . HOH I 3 .   ? -31.202 -9.774  -38.943  1.00 33.63  ? 706 HOH C O     1 
HETATM 12589 O O     . HOH I 3 .   ? 0.000   1.179   -72.363  0.50 67.45  ? 707 HOH C O     1 
HETATM 12590 O O     . HOH I 3 .   ? -36.549 -13.021 -53.005  1.00 44.05  ? 708 HOH C O     1 
HETATM 12591 O O     . HOH I 3 .   ? -24.934 6.541   -42.794  1.00 40.18  ? 709 HOH C O     1 
HETATM 12592 O O     . HOH I 3 .   ? -22.635 1.770   -65.711  1.00 57.15  ? 710 HOH C O     1 
HETATM 12593 O O     . HOH I 3 .   ? -22.505 4.610   -59.653  1.00 32.38  ? 711 HOH C O     1 
HETATM 12594 O O     . HOH I 3 .   ? -31.770 -0.584  -67.716  1.00 49.34  ? 712 HOH C O     1 
HETATM 12595 O O     . HOH I 3 .   ? -32.714 12.801  -60.465  1.00 42.79  ? 713 HOH C O     1 
HETATM 12596 O O     . HOH I 3 .   ? -16.912 2.510   -39.961  1.00 35.34  ? 714 HOH C O     1 
HETATM 12597 O O     . HOH I 3 .   ? -24.776 -9.459  -73.487  1.00 50.77  ? 715 HOH C O     1 
HETATM 12598 O O     . HOH I 3 .   ? -32.457 11.756  -57.827  1.00 34.96  ? 716 HOH C O     1 
HETATM 12599 O O     . HOH I 3 .   ? -23.651 -2.109  -37.568  1.00 44.21  ? 717 HOH C O     1 
HETATM 12600 O O     . HOH I 3 .   ? -12.918 6.389   -72.727  1.00 49.51  ? 718 HOH C O     1 
HETATM 12601 O O     . HOH I 3 .   ? -4.655  -6.533  -59.527  1.00 51.40  ? 719 HOH C O     1 
HETATM 12602 O O     . HOH I 3 .   ? -13.211 -13.398 -68.362  1.00 46.06  ? 720 HOH C O     1 
HETATM 12603 O O     . HOH I 3 .   ? -2.880  -3.824  -59.435  1.00 49.90  ? 721 HOH C O     1 
HETATM 12604 O O     . HOH I 3 .   ? -15.348 1.715   -76.146  1.00 55.90  ? 722 HOH C O     1 
HETATM 12605 O O     . HOH I 3 .   ? -10.277 -26.732 -53.491  1.00 47.38  ? 723 HOH C O     1 
HETATM 12606 O O     . HOH I 3 .   ? -26.071 -10.258 -70.734  1.00 60.46  ? 724 HOH C O     1 
HETATM 12607 O O     . HOH I 3 .   ? -34.118 11.151  -40.744  1.00 34.99  ? 725 HOH C O     1 
HETATM 12608 O O     . HOH I 3 .   ? -21.359 1.951   -89.006  1.00 63.91  ? 726 HOH C O     1 
HETATM 12609 O O     . HOH I 3 .   ? -22.802 5.044   -45.888  1.00 38.67  ? 727 HOH C O     1 
HETATM 12610 O O     . HOH I 3 .   ? -29.200 33.711  -63.207  1.00 48.24  ? 728 HOH C O     1 
HETATM 12611 O O     . HOH I 3 .   ? -33.566 -1.631  -54.983  1.00 49.61  ? 729 HOH C O     1 
HETATM 12612 O O     . HOH I 3 .   ? -19.950 3.998   -38.252  1.00 39.62  ? 730 HOH C O     1 
HETATM 12613 O O     . HOH I 3 .   ? -19.236 3.229   -40.821  1.00 42.71  ? 731 HOH C O     1 
HETATM 12614 O O     . HOH I 3 .   ? -19.681 11.878  -59.349  1.00 45.08  ? 732 HOH C O     1 
HETATM 12615 O O     . HOH I 3 .   ? -30.498 5.658   -58.754  1.00 38.03  ? 733 HOH C O     1 
HETATM 12616 O O     . HOH I 3 .   ? -31.712 8.873   -41.852  1.00 45.99  ? 734 HOH C O     1 
HETATM 12617 O O     . HOH I 3 .   ? -36.959 -17.058 -40.259  1.00 51.98  ? 735 HOH C O     1 
HETATM 12618 O O     . HOH I 3 .   ? -34.097 9.070   -83.755  1.00 48.83  ? 736 HOH C O     1 
HETATM 12619 O O     . HOH I 3 .   ? -43.450 -0.417  -50.286  1.00 43.60  ? 737 HOH C O     1 
HETATM 12620 O O     . HOH I 3 .   ? -20.483 5.809   -68.759  1.00 48.61  ? 738 HOH C O     1 
HETATM 12621 O O     . HOH I 3 .   ? -41.369 13.627  -62.776  1.00 61.84  ? 739 HOH C O     1 
HETATM 12622 O O     . HOH I 3 .   ? -17.173 -10.627 -38.923  1.00 27.10  ? 740 HOH C O     1 
HETATM 12623 O O     . HOH I 3 .   ? -10.600 -19.660 -61.210  1.00 52.59  ? 741 HOH C O     1 
HETATM 12624 O O     . HOH I 3 .   ? -7.371  -0.536  -87.467  1.00 43.40  ? 742 HOH C O     1 
HETATM 12625 O O     . HOH I 3 .   ? -42.508 2.621   -70.822  1.00 49.11  ? 743 HOH C O     1 
HETATM 12626 O O     . HOH I 3 .   ? -8.444  -18.746 -60.361  1.00 45.93  ? 744 HOH C O     1 
HETATM 12627 O O     . HOH I 3 .   ? -12.065 -10.134 -89.745  1.00 42.23  ? 745 HOH C O     1 
HETATM 12628 O O     . HOH I 3 .   ? -2.980  10.353  -76.769  1.00 64.31  ? 746 HOH C O     1 
HETATM 12629 O O     . HOH I 3 .   ? -33.809 24.872  -57.559  1.00 44.29  ? 747 HOH C O     1 
HETATM 12630 O O     . HOH I 3 .   ? -6.549  8.530   -84.991  1.00 41.20  ? 748 HOH C O     1 
HETATM 12631 O O     . HOH I 3 .   ? -25.369 17.602  -57.538  1.00 38.03  ? 749 HOH C O     1 
HETATM 12632 O O     . HOH I 3 .   ? -35.067 -0.248  -41.029  1.00 26.12  ? 750 HOH C O     1 
HETATM 12633 O O     . HOH I 3 .   ? -30.041 22.423  -59.345  1.00 39.96  ? 751 HOH C O     1 
HETATM 12634 O O     . HOH I 3 .   ? -21.769 30.282  -66.080  1.00 47.05  ? 752 HOH C O     1 
HETATM 12635 O O     . HOH I 3 .   ? -22.989 19.745  -57.209  1.00 39.59  ? 753 HOH C O     1 
# 
