data_8S53
# 
_entry.id   8S53 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8S53         pdb_00008s53 10.2210/pdb8s53/pdb 
WWPDB D_1292136788 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-29 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8S53 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB 'Apo structure of CYP142'                                    2XKR unspecified 
PDB '7P5T contains CYP142 in complex with a different inhibitor' 7P5T unspecified 
PDB '7QQ7contains CYP142 in complex with a different inhibitor'  7QQ7 unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              david.leys@manchester.ac.uk 
_pdbx_contact_author.name_first         David 
_pdbx_contact_author.name_last          Leys 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4845-8443 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Snee, M.'     1 0000-0003-3138-4994 
'Kavanagh, M.' 2 0000-0002-4735-1559 
'Levy, C.'     3 0000-0002-9724-310X 
'Leys, D.'     4 0000-0003-4845-8443 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? US ? ? primary Biorxiv                                          ?      ?    2692-8205 ? ? ?  ? ?   ?   
'Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism.' 2024 ? 
10.1101/2024.10.28.620643 39803573 ? ? 
? ? ? ? ? ? ? DK ? ? 1       'Acta Crystallogr., Sect. D: Biol. Crystallogr.' ABCRE6 0766 0907-4449 ? ? 75 ? 861 877 
'Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix'           2019 ? ? ? 
? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kavanagh, M.E.'      1  0000-0002-4735-1559 
primary 'McLean, K.J.'        2  0000-0002-7193-5044 
primary 'Gilbert, S.H.'       3  0000-0002-2760-9890 
primary 'Amadi, C.'           4  ?                   
primary 'Snee, M.'            5  0000-0003-3138-4994 
primary 'Tunnicliffe, R.B.'   6  0000-0003-0499-4113 
primary 'Arora, K.'           7  ?                   
primary 'Boshoff, H.I.'       8  0000-0002-4333-206X 
primary 'Fanourakis, A.'      9  ?                   
primary 'Rebello-Lopez, M.J.' 10 ?                   
primary 'Ortega-Muro, F.'     11 ?                   
primary 'Levy, C.W.'          12 0000-0002-9724-310X 
primary 'Munro, A.W.'         13 ?                   
primary 'Leys, D.'            14 ?                   
primary 'Abell, C.'           15 ?                   
primary 'Coyne, A.G.'         16 0000-0003-0205-5630 
1       'Liebschner, D.'      17 ?                   
1       'Afonine, P.'         18 ?                   
1       'Baker, M.'           19 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Steroid C26-monooxygenase'       46616.746 1   1.14.15.28 ? ? ? 
2 non-polymer syn 4-benzylpyridine                  169.222   2   ?          ? ? ? 
3 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE' 616.487   1   ?          ? ? ? 
4 water       nat water                             18.015    425 ?          ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Cholest-4-en-3-one C26-monooxygenase,Cholest-4-en-3-one C26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming],Cholesterol C26-monooxygenase,Cholesterol C26-monooxygenase [(25R)-3beta-hydroxycholest-5-en-26-oate forming],Cytochrome P450 142,Steroid C27-monooxygenase
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGLVPRGSHMTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFS
NAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGD
MLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDEL
VMETLLILIGGDETTRHTLSGGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEK
MMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANF
VSGLESMPVVFTPSPPLG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGLVPRGSHMTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFS
NAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGD
MLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDEL
VMETLLILIGGDETTRHTLSGGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEK
MMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANF
VSGLESMPVVFTPSPPLG
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 4-benzylpyridine                  3QO 
3 'PROTOPORPHYRIN IX CONTAINING FE' HEM 
4 water                             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  THR n 
1 23  GLU n 
1 24  ALA n 
1 25  PRO n 
1 26  ASP n 
1 27  VAL n 
1 28  ASP n 
1 29  LEU n 
1 30  ALA n 
1 31  ASP n 
1 32  GLY n 
1 33  ASN n 
1 34  PHE n 
1 35  TYR n 
1 36  ALA n 
1 37  SER n 
1 38  ARG n 
1 39  GLU n 
1 40  ALA n 
1 41  ARG n 
1 42  ALA n 
1 43  ALA n 
1 44  TYR n 
1 45  ARG n 
1 46  TRP n 
1 47  MET n 
1 48  ARG n 
1 49  ALA n 
1 50  ASN n 
1 51  GLN n 
1 52  PRO n 
1 53  VAL n 
1 54  PHE n 
1 55  ARG n 
1 56  ASP n 
1 57  ARG n 
1 58  ASN n 
1 59  GLY n 
1 60  LEU n 
1 61  ALA n 
1 62  ALA n 
1 63  ALA n 
1 64  SER n 
1 65  THR n 
1 66  TYR n 
1 67  GLN n 
1 68  ALA n 
1 69  VAL n 
1 70  ILE n 
1 71  ASP n 
1 72  ALA n 
1 73  GLU n 
1 74  ARG n 
1 75  GLN n 
1 76  PRO n 
1 77  GLU n 
1 78  LEU n 
1 79  PHE n 
1 80  SER n 
1 81  ASN n 
1 82  ALA n 
1 83  GLY n 
1 84  GLY n 
1 85  ILE n 
1 86  ARG n 
1 87  PRO n 
1 88  ASP n 
1 89  GLN n 
1 90  PRO n 
1 91  ALA n 
1 92  LEU n 
1 93  PRO n 
1 94  MET n 
1 95  MET n 
1 96  ILE n 
1 97  ASP n 
1 98  MET n 
1 99  ASP n 
1 100 ASP n 
1 101 PRO n 
1 102 ALA n 
1 103 HIS n 
1 104 LEU n 
1 105 LEU n 
1 106 ARG n 
1 107 ARG n 
1 108 LYS n 
1 109 LEU n 
1 110 VAL n 
1 111 ASN n 
1 112 ALA n 
1 113 GLY n 
1 114 PHE n 
1 115 THR n 
1 116 ARG n 
1 117 LYS n 
1 118 ARG n 
1 119 VAL n 
1 120 LYS n 
1 121 ASP n 
1 122 LYS n 
1 123 GLU n 
1 124 ALA n 
1 125 SER n 
1 126 ILE n 
1 127 ALA n 
1 128 ALA n 
1 129 LEU n 
1 130 CYS n 
1 131 ASP n 
1 132 THR n 
1 133 LEU n 
1 134 ILE n 
1 135 ASP n 
1 136 ALA n 
1 137 VAL n 
1 138 CYS n 
1 139 GLU n 
1 140 ARG n 
1 141 GLY n 
1 142 GLU n 
1 143 CYS n 
1 144 ASP n 
1 145 PHE n 
1 146 VAL n 
1 147 ARG n 
1 148 ASP n 
1 149 LEU n 
1 150 ALA n 
1 151 ALA n 
1 152 PRO n 
1 153 LEU n 
1 154 PRO n 
1 155 MET n 
1 156 ALA n 
1 157 VAL n 
1 158 ILE n 
1 159 GLY n 
1 160 ASP n 
1 161 MET n 
1 162 LEU n 
1 163 GLY n 
1 164 VAL n 
1 165 ARG n 
1 166 PRO n 
1 167 GLU n 
1 168 GLN n 
1 169 ARG n 
1 170 ASP n 
1 171 MET n 
1 172 PHE n 
1 173 LEU n 
1 174 ARG n 
1 175 TRP n 
1 176 SER n 
1 177 ASP n 
1 178 ASP n 
1 179 LEU n 
1 180 VAL n 
1 181 THR n 
1 182 PHE n 
1 183 LEU n 
1 184 SER n 
1 185 SER n 
1 186 HIS n 
1 187 VAL n 
1 188 SER n 
1 189 GLN n 
1 190 GLU n 
1 191 ASP n 
1 192 PHE n 
1 193 GLN n 
1 194 ILE n 
1 195 THR n 
1 196 MET n 
1 197 ASP n 
1 198 ALA n 
1 199 PHE n 
1 200 ALA n 
1 201 ALA n 
1 202 TYR n 
1 203 ASN n 
1 204 ASP n 
1 205 PHE n 
1 206 THR n 
1 207 ARG n 
1 208 ALA n 
1 209 THR n 
1 210 ILE n 
1 211 ALA n 
1 212 ALA n 
1 213 ARG n 
1 214 ARG n 
1 215 ALA n 
1 216 ASP n 
1 217 PRO n 
1 218 THR n 
1 219 ASP n 
1 220 ASP n 
1 221 LEU n 
1 222 VAL n 
1 223 SER n 
1 224 VAL n 
1 225 LEU n 
1 226 VAL n 
1 227 SER n 
1 228 SER n 
1 229 GLU n 
1 230 VAL n 
1 231 ASP n 
1 232 GLY n 
1 233 GLU n 
1 234 ARG n 
1 235 LEU n 
1 236 SER n 
1 237 ASP n 
1 238 ASP n 
1 239 GLU n 
1 240 LEU n 
1 241 VAL n 
1 242 MET n 
1 243 GLU n 
1 244 THR n 
1 245 LEU n 
1 246 LEU n 
1 247 ILE n 
1 248 LEU n 
1 249 ILE n 
1 250 GLY n 
1 251 GLY n 
1 252 ASP n 
1 253 GLU n 
1 254 THR n 
1 255 THR n 
1 256 ARG n 
1 257 HIS n 
1 258 THR n 
1 259 LEU n 
1 260 SER n 
1 261 GLY n 
1 262 GLY n 
1 263 THR n 
1 264 GLU n 
1 265 GLN n 
1 266 LEU n 
1 267 LEU n 
1 268 ARG n 
1 269 ASN n 
1 270 ARG n 
1 271 ASP n 
1 272 GLN n 
1 273 TRP n 
1 274 ASP n 
1 275 LEU n 
1 276 LEU n 
1 277 GLN n 
1 278 ARG n 
1 279 ASP n 
1 280 PRO n 
1 281 SER n 
1 282 LEU n 
1 283 LEU n 
1 284 PRO n 
1 285 GLY n 
1 286 ALA n 
1 287 ILE n 
1 288 GLU n 
1 289 GLU n 
1 290 MET n 
1 291 LEU n 
1 292 ARG n 
1 293 TRP n 
1 294 THR n 
1 295 ALA n 
1 296 PRO n 
1 297 VAL n 
1 298 LYS n 
1 299 ASN n 
1 300 MET n 
1 301 CYS n 
1 302 ARG n 
1 303 VAL n 
1 304 LEU n 
1 305 THR n 
1 306 ALA n 
1 307 ASP n 
1 308 THR n 
1 309 GLU n 
1 310 PHE n 
1 311 HIS n 
1 312 GLY n 
1 313 THR n 
1 314 ALA n 
1 315 LEU n 
1 316 CYS n 
1 317 ALA n 
1 318 GLY n 
1 319 GLU n 
1 320 LYS n 
1 321 MET n 
1 322 MET n 
1 323 LEU n 
1 324 LEU n 
1 325 PHE n 
1 326 GLU n 
1 327 SER n 
1 328 ALA n 
1 329 ASN n 
1 330 PHE n 
1 331 ASP n 
1 332 GLU n 
1 333 ALA n 
1 334 VAL n 
1 335 PHE n 
1 336 CYS n 
1 337 GLU n 
1 338 PRO n 
1 339 GLU n 
1 340 LYS n 
1 341 PHE n 
1 342 ASP n 
1 343 VAL n 
1 344 GLN n 
1 345 ARG n 
1 346 ASN n 
1 347 PRO n 
1 348 ASN n 
1 349 SER n 
1 350 HIS n 
1 351 LEU n 
1 352 ALA n 
1 353 PHE n 
1 354 GLY n 
1 355 PHE n 
1 356 GLY n 
1 357 THR n 
1 358 HIS n 
1 359 PHE n 
1 360 CYS n 
1 361 LEU n 
1 362 GLY n 
1 363 ASN n 
1 364 GLN n 
1 365 LEU n 
1 366 ALA n 
1 367 ARG n 
1 368 LEU n 
1 369 GLU n 
1 370 LEU n 
1 371 SER n 
1 372 LEU n 
1 373 MET n 
1 374 THR n 
1 375 GLU n 
1 376 ARG n 
1 377 VAL n 
1 378 LEU n 
1 379 ARG n 
1 380 ARG n 
1 381 LEU n 
1 382 PRO n 
1 383 ASP n 
1 384 LEU n 
1 385 ARG n 
1 386 LEU n 
1 387 VAL n 
1 388 ALA n 
1 389 ASP n 
1 390 ASP n 
1 391 SER n 
1 392 VAL n 
1 393 LEU n 
1 394 PRO n 
1 395 LEU n 
1 396 ARG n 
1 397 PRO n 
1 398 ALA n 
1 399 ASN n 
1 400 PHE n 
1 401 VAL n 
1 402 SER n 
1 403 GLY n 
1 404 LEU n 
1 405 GLU n 
1 406 SER n 
1 407 MET n 
1 408 PRO n 
1 409 VAL n 
1 410 VAL n 
1 411 PHE n 
1 412 THR n 
1 413 PRO n 
1 414 SER n 
1 415 PRO n 
1 416 PRO n 
1 417 LEU n 
1 418 GLY n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   418 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'cyp142, cyp142A1, Rv3518c, MTV023.25c' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Mycobacterium tuberculosis H37Rv' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     83332 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 25618 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              C41 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
3QO non-polymer         . 4-benzylpyridine                  ?    'C12 H11 N'        169.222 
ALA 'L-peptide linking' y ALANINE                           ?    'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                          ?    'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ?    'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ?    'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE                          ?    'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ?    'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ?    'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                           ?    'C2 H5 N O2'       75.067  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE' HEME 'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                         ?    'C6 H10 N3 O2 1'   156.162 
HOH non-polymer         . WATER                             ?    'H2 O'             18.015  
ILE 'L-peptide linking' y ISOLEUCINE                        ?    'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                           ?    'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                            ?    'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                        ?    'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE                     ?    'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                           ?    'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                            ?    'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                         ?    'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ?    'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                          ?    'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                            ?    'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -19 ?   ?   ?   A . n 
A 1 2   GLY 2   -18 ?   ?   ?   A . n 
A 1 3   SER 3   -17 ?   ?   ?   A . n 
A 1 4   SER 4   -16 ?   ?   ?   A . n 
A 1 5   HIS 5   -15 ?   ?   ?   A . n 
A 1 6   HIS 6   -14 ?   ?   ?   A . n 
A 1 7   HIS 7   -13 ?   ?   ?   A . n 
A 1 8   HIS 8   -12 ?   ?   ?   A . n 
A 1 9   HIS 9   -11 ?   ?   ?   A . n 
A 1 10  HIS 10  -10 ?   ?   ?   A . n 
A 1 11  SER 11  -9  ?   ?   ?   A . n 
A 1 12  SER 12  -8  ?   ?   ?   A . n 
A 1 13  GLY 13  -7  ?   ?   ?   A . n 
A 1 14  LEU 14  -6  ?   ?   ?   A . n 
A 1 15  VAL 15  -5  ?   ?   ?   A . n 
A 1 16  PRO 16  -4  ?   ?   ?   A . n 
A 1 17  ARG 17  -3  ?   ?   ?   A . n 
A 1 18  GLY 18  -2  ?   ?   ?   A . n 
A 1 19  SER 19  -1  ?   ?   ?   A . n 
A 1 20  HIS 20  0   ?   ?   ?   A . n 
A 1 21  MET 21  1   ?   ?   ?   A . n 
A 1 22  THR 22  2   ?   ?   ?   A . n 
A 1 23  GLU 23  3   3   GLU GLU A . n 
A 1 24  ALA 24  4   4   ALA ALA A . n 
A 1 25  PRO 25  5   5   PRO PRO A . n 
A 1 26  ASP 26  6   6   ASP ASP A . n 
A 1 27  VAL 27  7   7   VAL VAL A . n 
A 1 28  ASP 28  8   8   ASP ASP A . n 
A 1 29  LEU 29  9   9   LEU LEU A . n 
A 1 30  ALA 30  10  10  ALA ALA A . n 
A 1 31  ASP 31  11  11  ASP ASP A . n 
A 1 32  GLY 32  12  12  GLY GLY A . n 
A 1 33  ASN 33  13  13  ASN ASN A . n 
A 1 34  PHE 34  14  14  PHE PHE A . n 
A 1 35  TYR 35  15  15  TYR TYR A . n 
A 1 36  ALA 36  16  16  ALA ALA A . n 
A 1 37  SER 37  17  17  SER SER A . n 
A 1 38  ARG 38  18  18  ARG ARG A . n 
A 1 39  GLU 39  19  19  GLU GLU A . n 
A 1 40  ALA 40  20  20  ALA ALA A . n 
A 1 41  ARG 41  21  21  ARG ARG A . n 
A 1 42  ALA 42  22  22  ALA ALA A . n 
A 1 43  ALA 43  23  23  ALA ALA A . n 
A 1 44  TYR 44  24  24  TYR TYR A . n 
A 1 45  ARG 45  25  25  ARG ARG A . n 
A 1 46  TRP 46  26  26  TRP TRP A . n 
A 1 47  MET 47  27  27  MET MET A . n 
A 1 48  ARG 48  28  28  ARG ARG A . n 
A 1 49  ALA 49  29  29  ALA ALA A . n 
A 1 50  ASN 50  30  30  ASN ASN A . n 
A 1 51  GLN 51  31  31  GLN GLN A . n 
A 1 52  PRO 52  32  32  PRO PRO A . n 
A 1 53  VAL 53  33  33  VAL VAL A . n 
A 1 54  PHE 54  34  34  PHE PHE A . n 
A 1 55  ARG 55  35  35  ARG ARG A . n 
A 1 56  ASP 56  36  36  ASP ASP A . n 
A 1 57  ARG 57  37  37  ARG ARG A . n 
A 1 58  ASN 58  38  38  ASN ASN A . n 
A 1 59  GLY 59  39  39  GLY GLY A . n 
A 1 60  LEU 60  40  40  LEU LEU A . n 
A 1 61  ALA 61  41  41  ALA ALA A . n 
A 1 62  ALA 62  42  42  ALA ALA A . n 
A 1 63  ALA 63  43  43  ALA ALA A . n 
A 1 64  SER 64  44  44  SER SER A . n 
A 1 65  THR 65  45  45  THR THR A . n 
A 1 66  TYR 66  46  46  TYR TYR A . n 
A 1 67  GLN 67  47  47  GLN GLN A . n 
A 1 68  ALA 68  48  48  ALA ALA A . n 
A 1 69  VAL 69  49  49  VAL VAL A . n 
A 1 70  ILE 70  50  50  ILE ILE A . n 
A 1 71  ASP 71  51  51  ASP ASP A . n 
A 1 72  ALA 72  52  52  ALA ALA A . n 
A 1 73  GLU 73  53  53  GLU GLU A . n 
A 1 74  ARG 74  54  54  ARG ARG A . n 
A 1 75  GLN 75  55  55  GLN GLN A . n 
A 1 76  PRO 76  56  56  PRO PRO A . n 
A 1 77  GLU 77  57  57  GLU GLU A . n 
A 1 78  LEU 78  58  58  LEU LEU A . n 
A 1 79  PHE 79  59  59  PHE PHE A . n 
A 1 80  SER 80  60  60  SER SER A . n 
A 1 81  ASN 81  61  61  ASN ASN A . n 
A 1 82  ALA 82  62  62  ALA ALA A . n 
A 1 83  GLY 83  63  63  GLY GLY A . n 
A 1 84  GLY 84  64  64  GLY GLY A . n 
A 1 85  ILE 85  65  65  ILE ILE A . n 
A 1 86  ARG 86  66  66  ARG ARG A . n 
A 1 87  PRO 87  67  67  PRO PRO A . n 
A 1 88  ASP 88  68  68  ASP ASP A . n 
A 1 89  GLN 89  69  69  GLN GLN A . n 
A 1 90  PRO 90  70  70  PRO PRO A . n 
A 1 91  ALA 91  71  71  ALA ALA A . n 
A 1 92  LEU 92  72  72  LEU LEU A . n 
A 1 93  PRO 93  73  73  PRO PRO A . n 
A 1 94  MET 94  74  74  MET MET A . n 
A 1 95  MET 95  75  75  MET MET A . n 
A 1 96  ILE 96  76  76  ILE ILE A . n 
A 1 97  ASP 97  77  77  ASP ASP A . n 
A 1 98  MET 98  78  78  MET MET A . n 
A 1 99  ASP 99  79  79  ASP ASP A . n 
A 1 100 ASP 100 80  80  ASP ASP A . n 
A 1 101 PRO 101 81  81  PRO PRO A . n 
A 1 102 ALA 102 82  82  ALA ALA A . n 
A 1 103 HIS 103 83  83  HIS HIS A . n 
A 1 104 LEU 104 84  84  LEU LEU A . n 
A 1 105 LEU 105 85  85  LEU LEU A . n 
A 1 106 ARG 106 86  86  ARG ARG A . n 
A 1 107 ARG 107 87  87  ARG ARG A . n 
A 1 108 LYS 108 88  88  LYS LYS A . n 
A 1 109 LEU 109 89  89  LEU LEU A . n 
A 1 110 VAL 110 90  90  VAL VAL A . n 
A 1 111 ASN 111 91  91  ASN ASN A . n 
A 1 112 ALA 112 92  92  ALA ALA A . n 
A 1 113 GLY 113 93  93  GLY GLY A . n 
A 1 114 PHE 114 94  94  PHE PHE A . n 
A 1 115 THR 115 95  95  THR THR A . n 
A 1 116 ARG 116 96  96  ARG ARG A . n 
A 1 117 LYS 117 97  97  LYS LYS A . n 
A 1 118 ARG 118 98  98  ARG ARG A . n 
A 1 119 VAL 119 99  99  VAL VAL A . n 
A 1 120 LYS 120 100 100 LYS LYS A . n 
A 1 121 ASP 121 101 101 ASP ASP A . n 
A 1 122 LYS 122 102 102 LYS LYS A . n 
A 1 123 GLU 123 103 103 GLU GLU A . n 
A 1 124 ALA 124 104 104 ALA ALA A . n 
A 1 125 SER 125 105 105 SER SER A . n 
A 1 126 ILE 126 106 106 ILE ILE A . n 
A 1 127 ALA 127 107 107 ALA ALA A . n 
A 1 128 ALA 128 108 108 ALA ALA A . n 
A 1 129 LEU 129 109 109 LEU LEU A . n 
A 1 130 CYS 130 110 110 CYS CYS A . n 
A 1 131 ASP 131 111 111 ASP ASP A . n 
A 1 132 THR 132 112 112 THR THR A . n 
A 1 133 LEU 133 113 113 LEU LEU A . n 
A 1 134 ILE 134 114 114 ILE ILE A . n 
A 1 135 ASP 135 115 115 ASP ASP A . n 
A 1 136 ALA 136 116 116 ALA ALA A . n 
A 1 137 VAL 137 117 117 VAL VAL A . n 
A 1 138 CYS 138 118 118 CYS CYS A . n 
A 1 139 GLU 139 119 119 GLU GLU A . n 
A 1 140 ARG 140 120 120 ARG ARG A . n 
A 1 141 GLY 141 121 121 GLY GLY A . n 
A 1 142 GLU 142 122 122 GLU GLU A . n 
A 1 143 CYS 143 123 123 CYS CYS A . n 
A 1 144 ASP 144 124 124 ASP ASP A . n 
A 1 145 PHE 145 125 125 PHE PHE A . n 
A 1 146 VAL 146 126 126 VAL VAL A . n 
A 1 147 ARG 147 127 127 ARG ARG A . n 
A 1 148 ASP 148 128 128 ASP ASP A . n 
A 1 149 LEU 149 129 129 LEU LEU A . n 
A 1 150 ALA 150 130 130 ALA ALA A . n 
A 1 151 ALA 151 131 131 ALA ALA A . n 
A 1 152 PRO 152 132 132 PRO PRO A . n 
A 1 153 LEU 153 133 133 LEU LEU A . n 
A 1 154 PRO 154 134 134 PRO PRO A . n 
A 1 155 MET 155 135 135 MET MET A . n 
A 1 156 ALA 156 136 136 ALA ALA A . n 
A 1 157 VAL 157 137 137 VAL VAL A . n 
A 1 158 ILE 158 138 138 ILE ILE A . n 
A 1 159 GLY 159 139 139 GLY GLY A . n 
A 1 160 ASP 160 140 140 ASP ASP A . n 
A 1 161 MET 161 141 141 MET MET A . n 
A 1 162 LEU 162 142 142 LEU LEU A . n 
A 1 163 GLY 163 143 143 GLY GLY A . n 
A 1 164 VAL 164 144 144 VAL VAL A . n 
A 1 165 ARG 165 145 145 ARG ARG A . n 
A 1 166 PRO 166 146 146 PRO PRO A . n 
A 1 167 GLU 167 147 147 GLU GLU A . n 
A 1 168 GLN 168 148 148 GLN GLN A . n 
A 1 169 ARG 169 149 149 ARG ARG A . n 
A 1 170 ASP 170 150 150 ASP ASP A . n 
A 1 171 MET 171 151 151 MET MET A . n 
A 1 172 PHE 172 152 152 PHE PHE A . n 
A 1 173 LEU 173 153 153 LEU LEU A . n 
A 1 174 ARG 174 154 154 ARG ARG A . n 
A 1 175 TRP 175 155 155 TRP TRP A . n 
A 1 176 SER 176 156 156 SER SER A . n 
A 1 177 ASP 177 157 157 ASP ASP A . n 
A 1 178 ASP 178 158 158 ASP ASP A . n 
A 1 179 LEU 179 159 159 LEU LEU A . n 
A 1 180 VAL 180 160 160 VAL VAL A . n 
A 1 181 THR 181 161 161 THR THR A . n 
A 1 182 PHE 182 162 162 PHE PHE A . n 
A 1 183 LEU 183 163 163 LEU LEU A . n 
A 1 184 SER 184 164 164 SER SER A . n 
A 1 185 SER 185 165 165 SER SER A . n 
A 1 186 HIS 186 166 166 HIS HIS A . n 
A 1 187 VAL 187 167 167 VAL VAL A . n 
A 1 188 SER 188 168 168 SER SER A . n 
A 1 189 GLN 189 169 169 GLN GLN A . n 
A 1 190 GLU 190 170 170 GLU GLU A . n 
A 1 191 ASP 191 171 171 ASP ASP A . n 
A 1 192 PHE 192 172 172 PHE PHE A . n 
A 1 193 GLN 193 173 173 GLN GLN A . n 
A 1 194 ILE 194 174 174 ILE ILE A . n 
A 1 195 THR 195 175 175 THR THR A . n 
A 1 196 MET 196 176 176 MET MET A . n 
A 1 197 ASP 197 177 177 ASP ASP A . n 
A 1 198 ALA 198 178 178 ALA ALA A . n 
A 1 199 PHE 199 179 179 PHE PHE A . n 
A 1 200 ALA 200 180 180 ALA ALA A . n 
A 1 201 ALA 201 181 181 ALA ALA A . n 
A 1 202 TYR 202 182 182 TYR TYR A . n 
A 1 203 ASN 203 183 183 ASN ASN A . n 
A 1 204 ASP 204 184 184 ASP ASP A . n 
A 1 205 PHE 205 185 185 PHE PHE A . n 
A 1 206 THR 206 186 186 THR THR A . n 
A 1 207 ARG 207 187 187 ARG ARG A . n 
A 1 208 ALA 208 188 188 ALA ALA A . n 
A 1 209 THR 209 189 189 THR THR A . n 
A 1 210 ILE 210 190 190 ILE ILE A . n 
A 1 211 ALA 211 191 191 ALA ALA A . n 
A 1 212 ALA 212 192 192 ALA ALA A . n 
A 1 213 ARG 213 193 193 ARG ARG A . n 
A 1 214 ARG 214 194 194 ARG ARG A . n 
A 1 215 ALA 215 195 195 ALA ALA A . n 
A 1 216 ASP 216 196 196 ASP ASP A . n 
A 1 217 PRO 217 197 197 PRO PRO A . n 
A 1 218 THR 218 198 198 THR THR A . n 
A 1 219 ASP 219 199 199 ASP ASP A . n 
A 1 220 ASP 220 200 200 ASP ASP A . n 
A 1 221 LEU 221 201 201 LEU LEU A . n 
A 1 222 VAL 222 202 202 VAL VAL A . n 
A 1 223 SER 223 203 203 SER SER A . n 
A 1 224 VAL 224 204 204 VAL VAL A . n 
A 1 225 LEU 225 205 205 LEU LEU A . n 
A 1 226 VAL 226 206 206 VAL VAL A . n 
A 1 227 SER 227 207 207 SER SER A . n 
A 1 228 SER 228 208 208 SER SER A . n 
A 1 229 GLU 229 209 209 GLU GLU A . n 
A 1 230 VAL 230 210 210 VAL VAL A . n 
A 1 231 ASP 231 211 211 ASP ASP A . n 
A 1 232 GLY 232 212 212 GLY GLY A . n 
A 1 233 GLU 233 213 213 GLU GLU A . n 
A 1 234 ARG 234 214 214 ARG ARG A . n 
A 1 235 LEU 235 215 215 LEU LEU A . n 
A 1 236 SER 236 216 216 SER SER A . n 
A 1 237 ASP 237 217 217 ASP ASP A . n 
A 1 238 ASP 238 218 218 ASP ASP A . n 
A 1 239 GLU 239 219 219 GLU GLU A . n 
A 1 240 LEU 240 220 220 LEU LEU A . n 
A 1 241 VAL 241 221 221 VAL VAL A . n 
A 1 242 MET 242 222 222 MET MET A . n 
A 1 243 GLU 243 223 223 GLU GLU A . n 
A 1 244 THR 244 224 224 THR THR A . n 
A 1 245 LEU 245 225 225 LEU LEU A . n 
A 1 246 LEU 246 226 226 LEU LEU A . n 
A 1 247 ILE 247 227 227 ILE ILE A . n 
A 1 248 LEU 248 228 228 LEU LEU A . n 
A 1 249 ILE 249 229 229 ILE ILE A . n 
A 1 250 GLY 250 230 230 GLY GLY A . n 
A 1 251 GLY 251 231 231 GLY GLY A . n 
A 1 252 ASP 252 232 232 ASP ASP A . n 
A 1 253 GLU 253 233 233 GLU GLU A . n 
A 1 254 THR 254 234 234 THR THR A . n 
A 1 255 THR 255 235 235 THR THR A . n 
A 1 256 ARG 256 236 236 ARG ARG A . n 
A 1 257 HIS 257 237 237 HIS HIS A . n 
A 1 258 THR 258 238 238 THR THR A . n 
A 1 259 LEU 259 239 239 LEU LEU A . n 
A 1 260 SER 260 240 240 SER SER A . n 
A 1 261 GLY 261 241 241 GLY GLY A . n 
A 1 262 GLY 262 242 242 GLY GLY A . n 
A 1 263 THR 263 243 243 THR THR A . n 
A 1 264 GLU 264 244 244 GLU GLU A . n 
A 1 265 GLN 265 245 245 GLN GLN A . n 
A 1 266 LEU 266 246 246 LEU LEU A . n 
A 1 267 LEU 267 247 247 LEU LEU A . n 
A 1 268 ARG 268 248 248 ARG ARG A . n 
A 1 269 ASN 269 249 249 ASN ASN A . n 
A 1 270 ARG 270 250 250 ARG ARG A . n 
A 1 271 ASP 271 251 251 ASP ASP A . n 
A 1 272 GLN 272 252 252 GLN GLN A . n 
A 1 273 TRP 273 253 253 TRP TRP A . n 
A 1 274 ASP 274 254 254 ASP ASP A . n 
A 1 275 LEU 275 255 255 LEU LEU A . n 
A 1 276 LEU 276 256 256 LEU LEU A . n 
A 1 277 GLN 277 257 257 GLN GLN A . n 
A 1 278 ARG 278 258 258 ARG ARG A . n 
A 1 279 ASP 279 259 259 ASP ASP A . n 
A 1 280 PRO 280 260 260 PRO PRO A . n 
A 1 281 SER 281 261 261 SER SER A . n 
A 1 282 LEU 282 262 262 LEU LEU A . n 
A 1 283 LEU 283 263 263 LEU LEU A . n 
A 1 284 PRO 284 264 264 PRO PRO A . n 
A 1 285 GLY 285 265 265 GLY GLY A . n 
A 1 286 ALA 286 266 266 ALA ALA A . n 
A 1 287 ILE 287 267 267 ILE ILE A . n 
A 1 288 GLU 288 268 268 GLU GLU A . n 
A 1 289 GLU 289 269 269 GLU GLU A . n 
A 1 290 MET 290 270 270 MET MET A . n 
A 1 291 LEU 291 271 271 LEU LEU A . n 
A 1 292 ARG 292 272 272 ARG ARG A . n 
A 1 293 TRP 293 273 273 TRP TRP A . n 
A 1 294 THR 294 274 274 THR THR A . n 
A 1 295 ALA 295 275 275 ALA ALA A . n 
A 1 296 PRO 296 276 276 PRO PRO A . n 
A 1 297 VAL 297 277 277 VAL VAL A . n 
A 1 298 LYS 298 278 278 LYS LYS A . n 
A 1 299 ASN 299 279 279 ASN ASN A . n 
A 1 300 MET 300 280 280 MET MET A . n 
A 1 301 CYS 301 281 281 CYS CYS A . n 
A 1 302 ARG 302 282 282 ARG ARG A . n 
A 1 303 VAL 303 283 283 VAL VAL A . n 
A 1 304 LEU 304 284 284 LEU LEU A . n 
A 1 305 THR 305 285 285 THR THR A . n 
A 1 306 ALA 306 286 286 ALA ALA A . n 
A 1 307 ASP 307 287 287 ASP ASP A . n 
A 1 308 THR 308 288 288 THR THR A . n 
A 1 309 GLU 309 289 289 GLU GLU A . n 
A 1 310 PHE 310 290 290 PHE PHE A . n 
A 1 311 HIS 311 291 291 HIS HIS A . n 
A 1 312 GLY 312 292 292 GLY GLY A . n 
A 1 313 THR 313 293 293 THR THR A . n 
A 1 314 ALA 314 294 294 ALA ALA A . n 
A 1 315 LEU 315 295 295 LEU LEU A . n 
A 1 316 CYS 316 296 296 CYS CYS A . n 
A 1 317 ALA 317 297 297 ALA ALA A . n 
A 1 318 GLY 318 298 298 GLY GLY A . n 
A 1 319 GLU 319 299 299 GLU GLU A . n 
A 1 320 LYS 320 300 300 LYS LYS A . n 
A 1 321 MET 321 301 301 MET MET A . n 
A 1 322 MET 322 302 302 MET MET A . n 
A 1 323 LEU 323 303 303 LEU LEU A . n 
A 1 324 LEU 324 304 304 LEU LEU A . n 
A 1 325 PHE 325 305 305 PHE PHE A . n 
A 1 326 GLU 326 306 306 GLU GLU A . n 
A 1 327 SER 327 307 307 SER SER A . n 
A 1 328 ALA 328 308 308 ALA ALA A . n 
A 1 329 ASN 329 309 309 ASN ASN A . n 
A 1 330 PHE 330 310 310 PHE PHE A . n 
A 1 331 ASP 331 311 311 ASP ASP A . n 
A 1 332 GLU 332 312 312 GLU GLU A . n 
A 1 333 ALA 333 313 313 ALA ALA A . n 
A 1 334 VAL 334 314 314 VAL VAL A . n 
A 1 335 PHE 335 315 315 PHE PHE A . n 
A 1 336 CYS 336 316 316 CYS CYS A . n 
A 1 337 GLU 337 317 317 GLU GLU A . n 
A 1 338 PRO 338 318 318 PRO PRO A . n 
A 1 339 GLU 339 319 319 GLU GLU A . n 
A 1 340 LYS 340 320 320 LYS LYS A . n 
A 1 341 PHE 341 321 321 PHE PHE A . n 
A 1 342 ASP 342 322 322 ASP ASP A . n 
A 1 343 VAL 343 323 323 VAL VAL A . n 
A 1 344 GLN 344 324 324 GLN GLN A . n 
A 1 345 ARG 345 325 325 ARG ARG A . n 
A 1 346 ASN 346 326 326 ASN ASN A . n 
A 1 347 PRO 347 327 327 PRO PRO A . n 
A 1 348 ASN 348 328 328 ASN ASN A . n 
A 1 349 SER 349 329 329 SER SER A . n 
A 1 350 HIS 350 330 330 HIS HIS A . n 
A 1 351 LEU 351 331 331 LEU LEU A . n 
A 1 352 ALA 352 332 332 ALA ALA A . n 
A 1 353 PHE 353 333 333 PHE PHE A . n 
A 1 354 GLY 354 334 334 GLY GLY A . n 
A 1 355 PHE 355 335 335 PHE PHE A . n 
A 1 356 GLY 356 336 336 GLY GLY A . n 
A 1 357 THR 357 337 337 THR THR A . n 
A 1 358 HIS 358 338 338 HIS HIS A . n 
A 1 359 PHE 359 339 339 PHE PHE A . n 
A 1 360 CYS 360 340 340 CYS CYS A . n 
A 1 361 LEU 361 341 341 LEU LEU A . n 
A 1 362 GLY 362 342 342 GLY GLY A . n 
A 1 363 ASN 363 343 343 ASN ASN A . n 
A 1 364 GLN 364 344 344 GLN GLN A . n 
A 1 365 LEU 365 345 345 LEU LEU A . n 
A 1 366 ALA 366 346 346 ALA ALA A . n 
A 1 367 ARG 367 347 347 ARG ARG A . n 
A 1 368 LEU 368 348 348 LEU LEU A . n 
A 1 369 GLU 369 349 349 GLU GLU A . n 
A 1 370 LEU 370 350 350 LEU LEU A . n 
A 1 371 SER 371 351 351 SER SER A . n 
A 1 372 LEU 372 352 352 LEU LEU A . n 
A 1 373 MET 373 353 353 MET MET A . n 
A 1 374 THR 374 354 354 THR THR A . n 
A 1 375 GLU 375 355 355 GLU GLU A . n 
A 1 376 ARG 376 356 356 ARG ARG A . n 
A 1 377 VAL 377 357 357 VAL VAL A . n 
A 1 378 LEU 378 358 358 LEU LEU A . n 
A 1 379 ARG 379 359 359 ARG ARG A . n 
A 1 380 ARG 380 360 360 ARG ARG A . n 
A 1 381 LEU 381 361 361 LEU LEU A . n 
A 1 382 PRO 382 362 362 PRO PRO A . n 
A 1 383 ASP 383 363 363 ASP ASP A . n 
A 1 384 LEU 384 364 364 LEU LEU A . n 
A 1 385 ARG 385 365 365 ARG ARG A . n 
A 1 386 LEU 386 366 366 LEU LEU A . n 
A 1 387 VAL 387 367 367 VAL VAL A . n 
A 1 388 ALA 388 368 368 ALA ALA A . n 
A 1 389 ASP 389 369 369 ASP ASP A . n 
A 1 390 ASP 390 370 370 ASP ASP A . n 
A 1 391 SER 391 371 371 SER SER A . n 
A 1 392 VAL 392 372 372 VAL VAL A . n 
A 1 393 LEU 393 373 373 LEU LEU A . n 
A 1 394 PRO 394 374 374 PRO PRO A . n 
A 1 395 LEU 395 375 375 LEU LEU A . n 
A 1 396 ARG 396 376 376 ARG ARG A . n 
A 1 397 PRO 397 377 377 PRO PRO A . n 
A 1 398 ALA 398 378 378 ALA ALA A . n 
A 1 399 ASN 399 379 379 ASN ASN A . n 
A 1 400 PHE 400 380 380 PHE PHE A . n 
A 1 401 VAL 401 381 381 VAL VAL A . n 
A 1 402 SER 402 382 382 SER SER A . n 
A 1 403 GLY 403 383 383 GLY GLY A . n 
A 1 404 LEU 404 384 384 LEU LEU A . n 
A 1 405 GLU 405 385 385 GLU GLU A . n 
A 1 406 SER 406 386 386 SER SER A . n 
A 1 407 MET 407 387 387 MET MET A . n 
A 1 408 PRO 408 388 388 PRO PRO A . n 
A 1 409 VAL 409 389 389 VAL VAL A . n 
A 1 410 VAL 410 390 390 VAL VAL A . n 
A 1 411 PHE 411 391 391 PHE PHE A . n 
A 1 412 THR 412 392 392 THR THR A . n 
A 1 413 PRO 413 393 393 PRO PRO A . n 
A 1 414 SER 414 394 394 SER SER A . n 
A 1 415 PRO 415 395 395 PRO PRO A . n 
A 1 416 PRO 416 396 396 PRO PRO A . n 
A 1 417 LEU 417 397 397 LEU LEU A . n 
A 1 418 GLY 418 398 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        3QO 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   3QO 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 3QO 1   401 401 3QO 170 A . 
C 2 3QO 1   402 402 3QO 170 A . 
D 3 HEM 1   403 1   HEM HEM A . 
E 4 HOH 1   501 50  HOH HOH A . 
E 4 HOH 2   502 170 HOH HOH A . 
E 4 HOH 3   503 227 HOH HOH A . 
E 4 HOH 4   504 218 HOH HOH A . 
E 4 HOH 5   505 272 HOH HOH A . 
E 4 HOH 6   506 415 HOH HOH A . 
E 4 HOH 7   507 403 HOH HOH A . 
E 4 HOH 8   508 244 HOH HOH A . 
E 4 HOH 9   509 104 HOH HOH A . 
E 4 HOH 10  510 427 HOH HOH A . 
E 4 HOH 11  511 320 HOH HOH A . 
E 4 HOH 12  512 312 HOH HOH A . 
E 4 HOH 13  513 322 HOH HOH A . 
E 4 HOH 14  514 87  HOH HOH A . 
E 4 HOH 15  515 228 HOH HOH A . 
E 4 HOH 16  516 120 HOH HOH A . 
E 4 HOH 17  517 211 HOH HOH A . 
E 4 HOH 18  518 336 HOH HOH A . 
E 4 HOH 19  519 115 HOH HOH A . 
E 4 HOH 20  520 248 HOH HOH A . 
E 4 HOH 21  521 131 HOH HOH A . 
E 4 HOH 22  522 38  HOH HOH A . 
E 4 HOH 23  523 310 HOH HOH A . 
E 4 HOH 24  524 331 HOH HOH A . 
E 4 HOH 25  525 19  HOH HOH A . 
E 4 HOH 26  526 235 HOH HOH A . 
E 4 HOH 27  527 421 HOH HOH A . 
E 4 HOH 28  528 145 HOH HOH A . 
E 4 HOH 29  529 64  HOH HOH A . 
E 4 HOH 30  530 40  HOH HOH A . 
E 4 HOH 31  531 417 HOH HOH A . 
E 4 HOH 32  532 201 HOH HOH A . 
E 4 HOH 33  533 143 HOH HOH A . 
E 4 HOH 34  534 14  HOH HOH A . 
E 4 HOH 35  535 27  HOH HOH A . 
E 4 HOH 36  536 327 HOH HOH A . 
E 4 HOH 37  537 367 HOH HOH A . 
E 4 HOH 38  538 135 HOH HOH A . 
E 4 HOH 39  539 66  HOH HOH A . 
E 4 HOH 40  540 12  HOH HOH A . 
E 4 HOH 41  541 332 HOH HOH A . 
E 4 HOH 42  542 226 HOH HOH A . 
E 4 HOH 43  543 9   HOH HOH A . 
E 4 HOH 44  544 76  HOH HOH A . 
E 4 HOH 45  545 372 HOH HOH A . 
E 4 HOH 46  546 71  HOH HOH A . 
E 4 HOH 47  547 32  HOH HOH A . 
E 4 HOH 48  548 412 HOH HOH A . 
E 4 HOH 49  549 114 HOH HOH A . 
E 4 HOH 50  550 204 HOH HOH A . 
E 4 HOH 51  551 41  HOH HOH A . 
E 4 HOH 52  552 325 HOH HOH A . 
E 4 HOH 53  553 174 HOH HOH A . 
E 4 HOH 54  554 383 HOH HOH A . 
E 4 HOH 55  555 53  HOH HOH A . 
E 4 HOH 56  556 317 HOH HOH A . 
E 4 HOH 57  557 247 HOH HOH A . 
E 4 HOH 58  558 44  HOH HOH A . 
E 4 HOH 59  559 354 HOH HOH A . 
E 4 HOH 60  560 37  HOH HOH A . 
E 4 HOH 61  561 24  HOH HOH A . 
E 4 HOH 62  562 129 HOH HOH A . 
E 4 HOH 63  563 254 HOH HOH A . 
E 4 HOH 64  564 92  HOH HOH A . 
E 4 HOH 65  565 55  HOH HOH A . 
E 4 HOH 66  566 105 HOH HOH A . 
E 4 HOH 67  567 54  HOH HOH A . 
E 4 HOH 68  568 65  HOH HOH A . 
E 4 HOH 69  569 158 HOH HOH A . 
E 4 HOH 70  570 353 HOH HOH A . 
E 4 HOH 71  571 430 HOH HOH A . 
E 4 HOH 72  572 11  HOH HOH A . 
E 4 HOH 73  573 185 HOH HOH A . 
E 4 HOH 74  574 82  HOH HOH A . 
E 4 HOH 75  575 39  HOH HOH A . 
E 4 HOH 76  576 399 HOH HOH A . 
E 4 HOH 77  577 363 HOH HOH A . 
E 4 HOH 78  578 152 HOH HOH A . 
E 4 HOH 79  579 315 HOH HOH A . 
E 4 HOH 80  580 196 HOH HOH A . 
E 4 HOH 81  581 95  HOH HOH A . 
E 4 HOH 82  582 238 HOH HOH A . 
E 4 HOH 83  583 376 HOH HOH A . 
E 4 HOH 84  584 48  HOH HOH A . 
E 4 HOH 85  585 175 HOH HOH A . 
E 4 HOH 86  586 15  HOH HOH A . 
E 4 HOH 87  587 197 HOH HOH A . 
E 4 HOH 88  588 200 HOH HOH A . 
E 4 HOH 89  589 375 HOH HOH A . 
E 4 HOH 90  590 232 HOH HOH A . 
E 4 HOH 91  591 333 HOH HOH A . 
E 4 HOH 92  592 70  HOH HOH A . 
E 4 HOH 93  593 108 HOH HOH A . 
E 4 HOH 94  594 106 HOH HOH A . 
E 4 HOH 95  595 62  HOH HOH A . 
E 4 HOH 96  596 100 HOH HOH A . 
E 4 HOH 97  597 29  HOH HOH A . 
E 4 HOH 98  598 374 HOH HOH A . 
E 4 HOH 99  599 31  HOH HOH A . 
E 4 HOH 100 600 8   HOH HOH A . 
E 4 HOH 101 601 258 HOH HOH A . 
E 4 HOH 102 602 20  HOH HOH A . 
E 4 HOH 103 603 150 HOH HOH A . 
E 4 HOH 104 604 406 HOH HOH A . 
E 4 HOH 105 605 144 HOH HOH A . 
E 4 HOH 106 606 291 HOH HOH A . 
E 4 HOH 107 607 180 HOH HOH A . 
E 4 HOH 108 608 225 HOH HOH A . 
E 4 HOH 109 609 3   HOH HOH A . 
E 4 HOH 110 610 307 HOH HOH A . 
E 4 HOH 111 611 217 HOH HOH A . 
E 4 HOH 112 612 122 HOH HOH A . 
E 4 HOH 113 613 164 HOH HOH A . 
E 4 HOH 114 614 6   HOH HOH A . 
E 4 HOH 115 615 343 HOH HOH A . 
E 4 HOH 116 616 83  HOH HOH A . 
E 4 HOH 117 617 68  HOH HOH A . 
E 4 HOH 118 618 149 HOH HOH A . 
E 4 HOH 119 619 262 HOH HOH A . 
E 4 HOH 120 620 128 HOH HOH A . 
E 4 HOH 121 621 25  HOH HOH A . 
E 4 HOH 122 622 73  HOH HOH A . 
E 4 HOH 123 623 109 HOH HOH A . 
E 4 HOH 124 624 146 HOH HOH A . 
E 4 HOH 125 625 34  HOH HOH A . 
E 4 HOH 126 626 293 HOH HOH A . 
E 4 HOH 127 627 416 HOH HOH A . 
E 4 HOH 128 628 373 HOH HOH A . 
E 4 HOH 129 629 113 HOH HOH A . 
E 4 HOH 130 630 396 HOH HOH A . 
E 4 HOH 131 631 299 HOH HOH A . 
E 4 HOH 132 632 157 HOH HOH A . 
E 4 HOH 133 633 43  HOH HOH A . 
E 4 HOH 134 634 309 HOH HOH A . 
E 4 HOH 135 635 234 HOH HOH A . 
E 4 HOH 136 636 231 HOH HOH A . 
E 4 HOH 137 637 330 HOH HOH A . 
E 4 HOH 138 638 271 HOH HOH A . 
E 4 HOH 139 639 362 HOH HOH A . 
E 4 HOH 140 640 318 HOH HOH A . 
E 4 HOH 141 641 212 HOH HOH A . 
E 4 HOH 142 642 36  HOH HOH A . 
E 4 HOH 143 643 350 HOH HOH A . 
E 4 HOH 144 644 13  HOH HOH A . 
E 4 HOH 145 645 10  HOH HOH A . 
E 4 HOH 146 646 46  HOH HOH A . 
E 4 HOH 147 647 342 HOH HOH A . 
E 4 HOH 148 648 58  HOH HOH A . 
E 4 HOH 149 649 107 HOH HOH A . 
E 4 HOH 150 650 305 HOH HOH A . 
E 4 HOH 151 651 188 HOH HOH A . 
E 4 HOH 152 652 352 HOH HOH A . 
E 4 HOH 153 653 165 HOH HOH A . 
E 4 HOH 154 654 45  HOH HOH A . 
E 4 HOH 155 655 61  HOH HOH A . 
E 4 HOH 156 656 290 HOH HOH A . 
E 4 HOH 157 657 90  HOH HOH A . 
E 4 HOH 158 658 326 HOH HOH A . 
E 4 HOH 159 659 209 HOH HOH A . 
E 4 HOH 160 660 136 HOH HOH A . 
E 4 HOH 161 661 132 HOH HOH A . 
E 4 HOH 162 662 101 HOH HOH A . 
E 4 HOH 163 663 208 HOH HOH A . 
E 4 HOH 164 664 86  HOH HOH A . 
E 4 HOH 165 665 97  HOH HOH A . 
E 4 HOH 166 666 23  HOH HOH A . 
E 4 HOH 167 667 116 HOH HOH A . 
E 4 HOH 168 668 426 HOH HOH A . 
E 4 HOH 169 669 98  HOH HOH A . 
E 4 HOH 170 670 321 HOH HOH A . 
E 4 HOH 171 671 151 HOH HOH A . 
E 4 HOH 172 672 17  HOH HOH A . 
E 4 HOH 173 673 246 HOH HOH A . 
E 4 HOH 174 674 141 HOH HOH A . 
E 4 HOH 175 675 99  HOH HOH A . 
E 4 HOH 176 676 74  HOH HOH A . 
E 4 HOH 177 677 88  HOH HOH A . 
E 4 HOH 178 678 94  HOH HOH A . 
E 4 HOH 179 679 75  HOH HOH A . 
E 4 HOH 180 680 191 HOH HOH A . 
E 4 HOH 181 681 261 HOH HOH A . 
E 4 HOH 182 682 26  HOH HOH A . 
E 4 HOH 183 683 124 HOH HOH A . 
E 4 HOH 184 684 288 HOH HOH A . 
E 4 HOH 185 685 77  HOH HOH A . 
E 4 HOH 186 686 193 HOH HOH A . 
E 4 HOH 187 687 2   HOH HOH A . 
E 4 HOH 188 688 127 HOH HOH A . 
E 4 HOH 189 689 319 HOH HOH A . 
E 4 HOH 190 690 267 HOH HOH A . 
E 4 HOH 191 691 21  HOH HOH A . 
E 4 HOH 192 692 118 HOH HOH A . 
E 4 HOH 193 693 33  HOH HOH A . 
E 4 HOH 194 694 16  HOH HOH A . 
E 4 HOH 195 695 283 HOH HOH A . 
E 4 HOH 196 696 400 HOH HOH A . 
E 4 HOH 197 697 296 HOH HOH A . 
E 4 HOH 198 698 22  HOH HOH A . 
E 4 HOH 199 699 194 HOH HOH A . 
E 4 HOH 200 700 253 HOH HOH A . 
E 4 HOH 201 701 63  HOH HOH A . 
E 4 HOH 202 702 18  HOH HOH A . 
E 4 HOH 203 703 237 HOH HOH A . 
E 4 HOH 204 704 178 HOH HOH A . 
E 4 HOH 205 705 281 HOH HOH A . 
E 4 HOH 206 706 47  HOH HOH A . 
E 4 HOH 207 707 162 HOH HOH A . 
E 4 HOH 208 708 85  HOH HOH A . 
E 4 HOH 209 709 142 HOH HOH A . 
E 4 HOH 210 710 279 HOH HOH A . 
E 4 HOH 211 711 422 HOH HOH A . 
E 4 HOH 212 712 324 HOH HOH A . 
E 4 HOH 213 713 169 HOH HOH A . 
E 4 HOH 214 714 52  HOH HOH A . 
E 4 HOH 215 715 166 HOH HOH A . 
E 4 HOH 216 716 155 HOH HOH A . 
E 4 HOH 217 717 339 HOH HOH A . 
E 4 HOH 218 718 51  HOH HOH A . 
E 4 HOH 219 719 219 HOH HOH A . 
E 4 HOH 220 720 111 HOH HOH A . 
E 4 HOH 221 721 79  HOH HOH A . 
E 4 HOH 222 722 7   HOH HOH A . 
E 4 HOH 223 723 49  HOH HOH A . 
E 4 HOH 224 724 137 HOH HOH A . 
E 4 HOH 225 725 91  HOH HOH A . 
E 4 HOH 226 726 126 HOH HOH A . 
E 4 HOH 227 727 179 HOH HOH A . 
E 4 HOH 228 728 4   HOH HOH A . 
E 4 HOH 229 729 96  HOH HOH A . 
E 4 HOH 230 730 28  HOH HOH A . 
E 4 HOH 231 731 59  HOH HOH A . 
E 4 HOH 232 732 172 HOH HOH A . 
E 4 HOH 233 733 213 HOH HOH A . 
E 4 HOH 234 734 5   HOH HOH A . 
E 4 HOH 235 735 210 HOH HOH A . 
E 4 HOH 236 736 335 HOH HOH A . 
E 4 HOH 237 737 298 HOH HOH A . 
E 4 HOH 238 738 286 HOH HOH A . 
E 4 HOH 239 739 171 HOH HOH A . 
E 4 HOH 240 740 35  HOH HOH A . 
E 4 HOH 241 741 112 HOH HOH A . 
E 4 HOH 242 742 263 HOH HOH A . 
E 4 HOH 243 743 140 HOH HOH A . 
E 4 HOH 244 744 138 HOH HOH A . 
E 4 HOH 245 745 203 HOH HOH A . 
E 4 HOH 246 746 428 HOH HOH A . 
E 4 HOH 247 747 110 HOH HOH A . 
E 4 HOH 248 748 266 HOH HOH A . 
E 4 HOH 249 749 176 HOH HOH A . 
E 4 HOH 250 750 177 HOH HOH A . 
E 4 HOH 251 751 84  HOH HOH A . 
E 4 HOH 252 752 56  HOH HOH A . 
E 4 HOH 253 753 198 HOH HOH A . 
E 4 HOH 254 754 394 HOH HOH A . 
E 4 HOH 255 755 60  HOH HOH A . 
E 4 HOH 256 756 30  HOH HOH A . 
E 4 HOH 257 757 260 HOH HOH A . 
E 4 HOH 258 758 328 HOH HOH A . 
E 4 HOH 259 759 202 HOH HOH A . 
E 4 HOH 260 760 282 HOH HOH A . 
E 4 HOH 261 761 93  HOH HOH A . 
E 4 HOH 262 762 81  HOH HOH A . 
E 4 HOH 263 763 80  HOH HOH A . 
E 4 HOH 264 764 139 HOH HOH A . 
E 4 HOH 265 765 365 HOH HOH A . 
E 4 HOH 266 766 395 HOH HOH A . 
E 4 HOH 267 767 130 HOH HOH A . 
E 4 HOH 268 768 366 HOH HOH A . 
E 4 HOH 269 769 334 HOH HOH A . 
E 4 HOH 270 770 413 HOH HOH A . 
E 4 HOH 271 771 134 HOH HOH A . 
E 4 HOH 272 772 313 HOH HOH A . 
E 4 HOH 273 773 190 HOH HOH A . 
E 4 HOH 274 774 287 HOH HOH A . 
E 4 HOH 275 775 123 HOH HOH A . 
E 4 HOH 276 776 159 HOH HOH A . 
E 4 HOH 277 777 78  HOH HOH A . 
E 4 HOH 278 778 329 HOH HOH A . 
E 4 HOH 279 779 121 HOH HOH A . 
E 4 HOH 280 780 371 HOH HOH A . 
E 4 HOH 281 781 316 HOH HOH A . 
E 4 HOH 282 782 221 HOH HOH A . 
E 4 HOH 283 783 242 HOH HOH A . 
E 4 HOH 284 784 229 HOH HOH A . 
E 4 HOH 285 785 214 HOH HOH A . 
E 4 HOH 286 786 89  HOH HOH A . 
E 4 HOH 287 787 392 HOH HOH A . 
E 4 HOH 288 788 379 HOH HOH A . 
E 4 HOH 289 789 377 HOH HOH A . 
E 4 HOH 290 790 215 HOH HOH A . 
E 4 HOH 291 791 183 HOH HOH A . 
E 4 HOH 292 792 189 HOH HOH A . 
E 4 HOH 293 793 160 HOH HOH A . 
E 4 HOH 294 794 323 HOH HOH A . 
E 4 HOH 295 795 42  HOH HOH A . 
E 4 HOH 296 796 360 HOH HOH A . 
E 4 HOH 297 797 161 HOH HOH A . 
E 4 HOH 298 798 205 HOH HOH A . 
E 4 HOH 299 799 163 HOH HOH A . 
E 4 HOH 300 800 276 HOH HOH A . 
E 4 HOH 301 801 429 HOH HOH A . 
E 4 HOH 302 802 297 HOH HOH A . 
E 4 HOH 303 803 1   HOH HOH A . 
E 4 HOH 304 804 341 HOH HOH A . 
E 4 HOH 305 805 57  HOH HOH A . 
E 4 HOH 306 806 133 HOH HOH A . 
E 4 HOH 307 807 390 HOH HOH A . 
E 4 HOH 308 808 236 HOH HOH A . 
E 4 HOH 309 809 259 HOH HOH A . 
E 4 HOH 310 810 277 HOH HOH A . 
E 4 HOH 311 811 220 HOH HOH A . 
E 4 HOH 312 812 239 HOH HOH A . 
E 4 HOH 313 813 348 HOH HOH A . 
E 4 HOH 314 814 409 HOH HOH A . 
E 4 HOH 315 815 404 HOH HOH A . 
E 4 HOH 316 816 72  HOH HOH A . 
E 4 HOH 317 817 398 HOH HOH A . 
E 4 HOH 318 818 187 HOH HOH A . 
E 4 HOH 319 819 397 HOH HOH A . 
E 4 HOH 320 820 154 HOH HOH A . 
E 4 HOH 321 821 391 HOH HOH A . 
E 4 HOH 322 822 186 HOH HOH A . 
E 4 HOH 323 823 199 HOH HOH A . 
E 4 HOH 324 824 361 HOH HOH A . 
E 4 HOH 325 825 407 HOH HOH A . 
E 4 HOH 326 826 284 HOH HOH A . 
E 4 HOH 327 827 411 HOH HOH A . 
E 4 HOH 328 828 389 HOH HOH A . 
E 4 HOH 329 829 401 HOH HOH A . 
E 4 HOH 330 830 356 HOH HOH A . 
E 4 HOH 331 831 292 HOH HOH A . 
E 4 HOH 332 832 385 HOH HOH A . 
E 4 HOH 333 833 303 HOH HOH A . 
E 4 HOH 334 834 206 HOH HOH A . 
E 4 HOH 335 835 405 HOH HOH A . 
E 4 HOH 336 836 125 HOH HOH A . 
E 4 HOH 337 837 69  HOH HOH A . 
E 4 HOH 338 838 300 HOH HOH A . 
E 4 HOH 339 839 355 HOH HOH A . 
E 4 HOH 340 840 351 HOH HOH A . 
E 4 HOH 341 841 230 HOH HOH A . 
E 4 HOH 342 842 251 HOH HOH A . 
E 4 HOH 343 843 268 HOH HOH A . 
E 4 HOH 344 844 153 HOH HOH A . 
E 4 HOH 345 845 280 HOH HOH A . 
E 4 HOH 346 846 245 HOH HOH A . 
E 4 HOH 347 847 306 HOH HOH A . 
E 4 HOH 348 848 344 HOH HOH A . 
E 4 HOH 349 849 358 HOH HOH A . 
E 4 HOH 350 850 425 HOH HOH A . 
E 4 HOH 351 851 402 HOH HOH A . 
E 4 HOH 352 852 252 HOH HOH A . 
E 4 HOH 353 853 173 HOH HOH A . 
E 4 HOH 354 854 278 HOH HOH A . 
E 4 HOH 355 855 233 HOH HOH A . 
E 4 HOH 356 856 222 HOH HOH A . 
E 4 HOH 357 857 314 HOH HOH A . 
E 4 HOH 358 858 304 HOH HOH A . 
E 4 HOH 359 859 301 HOH HOH A . 
E 4 HOH 360 860 103 HOH HOH A . 
E 4 HOH 361 861 419 HOH HOH A . 
E 4 HOH 362 862 207 HOH HOH A . 
E 4 HOH 363 863 311 HOH HOH A . 
E 4 HOH 364 864 255 HOH HOH A . 
E 4 HOH 365 865 347 HOH HOH A . 
E 4 HOH 366 866 195 HOH HOH A . 
E 4 HOH 367 867 265 HOH HOH A . 
E 4 HOH 368 868 249 HOH HOH A . 
E 4 HOH 369 869 289 HOH HOH A . 
E 4 HOH 370 870 216 HOH HOH A . 
E 4 HOH 371 871 378 HOH HOH A . 
E 4 HOH 372 872 274 HOH HOH A . 
E 4 HOH 373 873 269 HOH HOH A . 
E 4 HOH 374 874 295 HOH HOH A . 
E 4 HOH 375 875 346 HOH HOH A . 
E 4 HOH 376 876 270 HOH HOH A . 
E 4 HOH 377 877 240 HOH HOH A . 
E 4 HOH 378 878 384 HOH HOH A . 
E 4 HOH 379 879 243 HOH HOH A . 
E 4 HOH 380 880 156 HOH HOH A . 
E 4 HOH 381 881 148 HOH HOH A . 
E 4 HOH 382 882 345 HOH HOH A . 
E 4 HOH 383 883 386 HOH HOH A . 
E 4 HOH 384 884 223 HOH HOH A . 
E 4 HOH 385 885 167 HOH HOH A . 
E 4 HOH 386 886 294 HOH HOH A . 
E 4 HOH 387 887 408 HOH HOH A . 
E 4 HOH 388 888 241 HOH HOH A . 
E 4 HOH 389 889 250 HOH HOH A . 
E 4 HOH 390 890 117 HOH HOH A . 
E 4 HOH 391 891 381 HOH HOH A . 
E 4 HOH 392 892 349 HOH HOH A . 
E 4 HOH 393 893 364 HOH HOH A . 
E 4 HOH 394 894 273 HOH HOH A . 
E 4 HOH 395 895 147 HOH HOH A . 
E 4 HOH 396 896 168 HOH HOH A . 
E 4 HOH 397 897 302 HOH HOH A . 
E 4 HOH 398 898 102 HOH HOH A . 
E 4 HOH 399 899 368 HOH HOH A . 
E 4 HOH 400 900 119 HOH HOH A . 
E 4 HOH 401 901 369 HOH HOH A . 
E 4 HOH 402 902 224 HOH HOH A . 
E 4 HOH 403 903 256 HOH HOH A . 
E 4 HOH 404 904 418 HOH HOH A . 
E 4 HOH 405 905 264 HOH HOH A . 
E 4 HOH 406 906 308 HOH HOH A . 
E 4 HOH 407 907 370 HOH HOH A . 
E 4 HOH 408 908 181 HOH HOH A . 
E 4 HOH 409 909 337 HOH HOH A . 
E 4 HOH 410 910 414 HOH HOH A . 
E 4 HOH 411 911 285 HOH HOH A . 
E 4 HOH 412 912 184 HOH HOH A . 
E 4 HOH 413 913 410 HOH HOH A . 
E 4 HOH 414 914 192 HOH HOH A . 
E 4 HOH 415 915 387 HOH HOH A . 
E 4 HOH 416 916 182 HOH HOH A . 
E 4 HOH 417 917 275 HOH HOH A . 
E 4 HOH 418 918 393 HOH HOH A . 
E 4 HOH 419 919 420 HOH HOH A . 
E 4 HOH 420 920 380 HOH HOH A . 
E 4 HOH 421 921 340 HOH HOH A . 
E 4 HOH 422 922 382 HOH HOH A . 
E 4 HOH 423 923 257 HOH HOH A . 
E 4 HOH 424 924 424 HOH HOH A . 
E 4 HOH 425 925 423 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 96  ? CG  ? A ARG 116 CG  
2  1 Y 1 A ARG 96  ? CD  ? A ARG 116 CD  
3  1 Y 1 A ARG 96  ? NE  ? A ARG 116 NE  
4  1 Y 1 A ARG 96  ? CZ  ? A ARG 116 CZ  
5  1 Y 1 A ARG 96  ? NH1 ? A ARG 116 NH1 
6  1 Y 1 A ARG 96  ? NH2 ? A ARG 116 NH2 
7  1 Y 1 A LYS 97  ? CG  ? A LYS 117 CG  
8  1 Y 1 A LYS 97  ? CD  ? A LYS 117 CD  
9  1 Y 1 A LYS 97  ? CE  ? A LYS 117 CE  
10 1 Y 1 A LYS 97  ? NZ  ? A LYS 117 NZ  
11 1 Y 1 A GLU 170 ? CG  ? A GLU 190 CG  
12 1 Y 1 A GLU 170 ? CD  ? A GLU 190 CD  
13 1 Y 1 A GLU 170 ? OE1 ? A GLU 190 OE1 
14 1 Y 1 A GLU 170 ? OE2 ? A GLU 190 OE2 
15 1 Y 1 A ASP 196 ? CG  ? A ASP 216 CG  
16 1 Y 1 A ASP 196 ? OD1 ? A ASP 216 OD1 
17 1 Y 1 A ASP 196 ? OD2 ? A ASP 216 OD2 
18 1 Y 1 A ASP 369 ? CG  ? A ASP 389 CG  
19 1 Y 1 A ASP 369 ? OD1 ? A ASP 389 OD1 
20 1 Y 1 A ASP 369 ? OD2 ? A ASP 389 OD2 
21 1 N 1 A 3QO 402 ? CAA ? C 3QO 1   CAA 
22 1 N 1 A 3QO 402 ? CAB ? C 3QO 1   CAB 
23 1 N 1 A 3QO 402 ? CAC ? C 3QO 1   CAC 
24 1 N 1 A 3QO 402 ? CAF ? C 3QO 1   CAF 
25 1 N 1 A 3QO 402 ? CAG ? C 3QO 1   CAG 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DIALS   ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8S53 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     55.458 
_cell.length_a_esd                 ? 
_cell.length_b                     65.772 
_cell.length_b_esd                 ? 
_cell.length_c                     130.655 
_cell.length_c_esd                 ? 
_cell.volume                       476576.296 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8S53 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8S53 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.56 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          51.87 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'10% PEG 550MME WITH 100 MM POTASSIUM THIOCYANATE AND 0.1 M SODIUM ACETATE AT A PH RANGE OF 5.0-6.0.' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     99 
_diffrn.ambient_temp_details             'N2 cryostream' 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'ADSC QUANTUM 315' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2013-06-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.92 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I04' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.92 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I04 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          24.61 
_reflns.entry_id                                       8S53 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.6 
_reflns.d_resolution_low                               65.77 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     62563 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                7.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          17 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.066 
_reflns.pdbx_Rpim_I_all                                0.023 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.062 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.6 
_reflns_shell.d_res_low                                     1.63 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.3 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2491 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               0.925 
_reflns_shell.pdbx_Rpim_I_all                               0.390 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.657 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.831 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               32.11 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8S53 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.60 
_refine.ls_d_res_low                             65.33 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     62483 
_refine.ls_number_reflns_R_free                  3120 
_refine.ls_number_reflns_R_work                  59363 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.84 
_refine.ls_percent_reflns_R_free                 4.99 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1571 
_refine.ls_R_factor_R_free                       0.1749 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1562 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 16.3619 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1757 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.60 
_refine_hist.d_res_low                        65.33 
_refine_hist.number_atoms_solvent             425 
_refine_hist.number_atoms_total               3560 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3071 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         64 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0116 ? 3234 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.1536 ? 4407 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0638 ? 485  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0136 ? 584  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 7.7624 ? 471  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.60 1.63  . . 113 2151 79.36  . . . . 0.2302 . . . . . . . . . . . 0.2203 
'X-RAY DIFFRACTION' 1.63 1.65  . . 144 2304 85.56  . . . . 0.2193 . . . . . . . . . . . 0.2565 
'X-RAY DIFFRACTION' 1.65 1.68  . . 130 2478 90.62  . . . . 0.2309 . . . . . . . . . . . 0.2436 
'X-RAY DIFFRACTION' 1.68 1.71  . . 140 2595 96.88  . . . . 0.2417 . . . . . . . . . . . 0.2639 
'X-RAY DIFFRACTION' 1.71 1.74  . . 130 2752 99.90  . . . . 0.2820 . . . . . . . . . . . 0.3094 
'X-RAY DIFFRACTION' 1.74 1.78  . . 156 2715 99.97  . . . . 0.2401 . . . . . . . . . . . 0.2268 
'X-RAY DIFFRACTION' 1.78 1.82  . . 129 2743 99.97  . . . . 0.2013 . . . . . . . . . . . 0.2480 
'X-RAY DIFFRACTION' 1.82 1.86  . . 143 2717 100.00 . . . . 0.1753 . . . . . . . . . . . 0.2097 
'X-RAY DIFFRACTION' 1.86 1.91  . . 129 2761 99.97  . . . . 0.1492 . . . . . . . . . . . 0.1609 
'X-RAY DIFFRACTION' 1.91 1.96  . . 133 2728 100.00 . . . . 0.1443 . . . . . . . . . . . 0.1694 
'X-RAY DIFFRACTION' 1.96 2.02  . . 143 2731 100.00 . . . . 0.1540 . . . . . . . . . . . 0.1799 
'X-RAY DIFFRACTION' 2.02 2.08  . . 153 2739 100.00 . . . . 0.1655 . . . . . . . . . . . 0.1881 
'X-RAY DIFFRACTION' 2.08 2.16  . . 139 2757 100.00 . . . . 0.1763 . . . . . . . . . . . 0.2018 
'X-RAY DIFFRACTION' 2.16 2.24  . . 162 2726 100.00 . . . . 0.1345 . . . . . . . . . . . 0.1728 
'X-RAY DIFFRACTION' 2.24 2.34  . . 132 2772 100.00 . . . . 0.1284 . . . . . . . . . . . 0.1453 
'X-RAY DIFFRACTION' 2.34 2.47  . . 143 2742 100.00 . . . . 0.1362 . . . . . . . . . . . 0.1391 
'X-RAY DIFFRACTION' 2.47 2.62  . . 133 2801 99.97  . . . . 0.1392 . . . . . . . . . . . 0.1691 
'X-RAY DIFFRACTION' 2.62 2.82  . . 138 2765 100.00 . . . . 0.1493 . . . . . . . . . . . 0.1993 
'X-RAY DIFFRACTION' 2.82 3.11  . . 156 2790 99.97  . . . . 0.1557 . . . . . . . . . . . 0.1577 
'X-RAY DIFFRACTION' 3.11 3.56  . . 166 2784 100.00 . . . . 0.1556 . . . . . . . . . . . 0.1907 
'X-RAY DIFFRACTION' 3.56 4.48  . . 156 2834 100.00 . . . . 0.1330 . . . . . . . . . . . 0.1408 
'X-RAY DIFFRACTION' 4.48 65.33 . . 152 2978 99.71  . . . . 0.1629 . . . . . . . . . . . 0.1683 
# 
_struct.entry_id                     8S53 
_struct.title                        
'X-ray crystal structure of CYP142 from Mycobacterium tuberculosis in complex with a fragment bound in two poses' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8S53 
_struct_keywords.text            
'CYP142, P450, cholesterol, cytochrome, tuberculosis, fragment, heme, CYP, iron, drug, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CP142_MYCTU 
_struct_ref.pdbx_db_accession          P9WPL5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFSNAGGIRPDQPALPMMIDMDD
PAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLV
TFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLS
GGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEK
FDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8S53 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 21 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 418 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P9WPL5 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  398 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       398 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8S53 MET A 1  ? UNP P9WPL5 ? ? 'initiating methionine' -19 1  
1 8S53 GLY A 2  ? UNP P9WPL5 ? ? 'expression tag'        -18 2  
1 8S53 SER A 3  ? UNP P9WPL5 ? ? 'expression tag'        -17 3  
1 8S53 SER A 4  ? UNP P9WPL5 ? ? 'expression tag'        -16 4  
1 8S53 HIS A 5  ? UNP P9WPL5 ? ? 'expression tag'        -15 5  
1 8S53 HIS A 6  ? UNP P9WPL5 ? ? 'expression tag'        -14 6  
1 8S53 HIS A 7  ? UNP P9WPL5 ? ? 'expression tag'        -13 7  
1 8S53 HIS A 8  ? UNP P9WPL5 ? ? 'expression tag'        -12 8  
1 8S53 HIS A 9  ? UNP P9WPL5 ? ? 'expression tag'        -11 9  
1 8S53 HIS A 10 ? UNP P9WPL5 ? ? 'expression tag'        -10 10 
1 8S53 SER A 11 ? UNP P9WPL5 ? ? 'expression tag'        -9  11 
1 8S53 SER A 12 ? UNP P9WPL5 ? ? 'expression tag'        -8  12 
1 8S53 GLY A 13 ? UNP P9WPL5 ? ? 'expression tag'        -7  13 
1 8S53 LEU A 14 ? UNP P9WPL5 ? ? 'expression tag'        -6  14 
1 8S53 VAL A 15 ? UNP P9WPL5 ? ? 'expression tag'        -5  15 
1 8S53 PRO A 16 ? UNP P9WPL5 ? ? 'expression tag'        -4  16 
1 8S53 ARG A 17 ? UNP P9WPL5 ? ? 'expression tag'        -3  17 
1 8S53 GLY A 18 ? UNP P9WPL5 ? ? 'expression tag'        -2  18 
1 8S53 SER A 19 ? UNP P9WPL5 ? ? 'expression tag'        -1  19 
1 8S53 HIS A 20 ? UNP P9WPL5 ? ? 'expression tag'        0   20 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1200  ? 
1 MORE         -26   ? 
1 'SSA (A^2)'  16040 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 31  ? SER A 37  ? ASP A 11  SER A 17  1 ? 7  
HELX_P HELX_P2  AA2 GLU A 39  ? GLN A 51  ? GLU A 19  GLN A 31  1 ? 13 
HELX_P HELX_P3  AA3 THR A 65  ? ARG A 74  ? THR A 45  ARG A 54  1 ? 10 
HELX_P HELX_P4  AA4 MET A 94  ? MET A 98  ? MET A 74  MET A 78  5 ? 5  
HELX_P HELX_P5  AA5 PRO A 101 ? ASN A 111 ? PRO A 81  ASN A 91  1 ? 11 
HELX_P HELX_P6  AA6 ALA A 112 ? PHE A 114 ? ALA A 92  PHE A 94  5 ? 3  
HELX_P HELX_P7  AA7 THR A 115 ? ASP A 121 ? THR A 95  ASP A 101 1 ? 7  
HELX_P HELX_P8  AA8 LYS A 122 ? ALA A 136 ? LYS A 102 ALA A 116 1 ? 15 
HELX_P HELX_P9  AA9 PHE A 145 ? LEU A 149 ? PHE A 125 LEU A 129 1 ? 5  
HELX_P HELX_P10 AB1 ALA A 151 ? GLY A 163 ? ALA A 131 GLY A 143 1 ? 13 
HELX_P HELX_P11 AB2 ARG A 165 ? GLU A 167 ? ARG A 145 GLU A 147 5 ? 3  
HELX_P HELX_P12 AB3 GLN A 168 ? SER A 184 ? GLN A 148 SER A 164 1 ? 17 
HELX_P HELX_P13 AB4 SER A 188 ? ASP A 216 ? SER A 168 ASP A 196 1 ? 29 
HELX_P HELX_P14 AB5 ASP A 220 ? SER A 228 ? ASP A 200 SER A 208 1 ? 9  
HELX_P HELX_P15 AB6 SER A 236 ? THR A 254 ? SER A 216 THR A 234 1 ? 19 
HELX_P HELX_P16 AB7 THR A 254 ? ASN A 269 ? THR A 234 ASN A 249 1 ? 16 
HELX_P HELX_P17 AB8 ASN A 269 ? ASP A 279 ? ASN A 249 ASP A 259 1 ? 11 
HELX_P HELX_P18 AB9 LEU A 282 ? ALA A 295 ? LEU A 262 ALA A 275 1 ? 14 
HELX_P HELX_P19 AC1 PHE A 325 ? PHE A 330 ? PHE A 305 PHE A 310 1 ? 6  
HELX_P HELX_P20 AC2 GLY A 362 ? LEU A 381 ? GLY A 342 LEU A 361 1 ? 20 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A CYS 360 SG  ? ? ? 1_555 D HEM . FE ? ? A CYS 340 A HEM 403 1_555 ? ? ? ? ? ? ? 2.345 ? ? 
metalc2 metalc ? ? B 3QO .   NAK ? ? ? 1_555 D HEM . FE ? ? A 3QO 401 A HEM 403 1_555 ? ? ? ? ? ? ? 2.071 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  SG ? A CYS 360 ? A CYS 340 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NA  ? D HEM . ? A HEM 403 ? 1_555 95.7  ? 
2  SG ? A CYS 360 ? A CYS 340 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NB  ? D HEM . ? A HEM 403 ? 1_555 85.5  ? 
3  NA ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NB  ? D HEM . ? A HEM 403 ? 1_555 90.1  ? 
4  SG ? A CYS 360 ? A CYS 340 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NC  ? D HEM . ? A HEM 403 ? 1_555 83.7  ? 
5  NA ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NC  ? D HEM . ? A HEM 403 ? 1_555 178.8 ? 
6  NB ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NC  ? D HEM . ? A HEM 403 ? 1_555 90.8  ? 
7  SG ? A CYS 360 ? A CYS 340 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 ND  ? D HEM . ? A HEM 403 ? 1_555 94.1  ? 
8  NA ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 ND  ? D HEM . ? A HEM 403 ? 1_555 90.7  ? 
9  NB ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 ND  ? D HEM . ? A HEM 403 ? 1_555 179.1 ? 
10 NC ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 ND  ? D HEM . ? A HEM 403 ? 1_555 88.3  ? 
11 SG ? A CYS 360 ? A CYS 340 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NAK ? B 3QO . ? A 3QO 401 ? 1_555 176.2 ? 
12 NA ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NAK ? B 3QO . ? A 3QO 401 ? 1_555 88.0  ? 
13 NB ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NAK ? B 3QO . ? A 3QO 401 ? 1_555 93.5  ? 
14 NC ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NAK ? B 3QO . ? A 3QO 401 ? 1_555 92.7  ? 
15 ND ? D HEM .   ? A HEM 403 ? 1_555 FE ? D HEM . ? A HEM 403 ? 1_555 NAK ? B 3QO . ? A 3QO 401 ? 1_555 86.9  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASP 100 A . ? ASP 80  A PRO 101 A ? PRO 81  A 1 5.72  
2 ASN 346 A . ? ASN 326 A PRO 347 A ? PRO 327 A 1 -1.75 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 53  ? ARG A 55  ? VAL A 33  ARG A 35  
AA1 2 ALA A 61  ? ALA A 63  ? ALA A 41  ALA A 43  
AA1 3 LYS A 320 ? LEU A 324 ? LYS A 300 LEU A 304 
AA1 4 ASN A 299 ? LEU A 304 ? ASN A 279 LEU A 284 
AA1 5 PHE A 79  ? SER A 80  ? PHE A 59  SER A 60  
AA2 1 GLU A 142 ? ASP A 144 ? GLU A 122 ASP A 124 
AA2 2 PRO A 408 ? VAL A 410 ? PRO A 388 VAL A 390 
AA2 3 ARG A 385 ? LEU A 386 ? ARG A 365 LEU A 366 
AA3 1 THR A 308 ? PHE A 310 ? THR A 288 PHE A 290 
AA3 2 THR A 313 ? LEU A 315 ? THR A 293 LEU A 295 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 54  ? N PHE A 34  O ALA A 62  ? O ALA A 42  
AA1 2 3 N ALA A 63  ? N ALA A 43  O MET A 322 ? O MET A 302 
AA1 3 4 O MET A 321 ? O MET A 301 N ARG A 302 ? N ARG A 282 
AA1 4 5 O VAL A 303 ? O VAL A 283 N SER A 80  ? N SER A 60  
AA2 1 2 N CYS A 143 ? N CYS A 123 O VAL A 409 ? O VAL A 389 
AA2 2 3 O VAL A 410 ? O VAL A 390 N ARG A 385 ? N ARG A 365 
AA3 1 2 N THR A 308 ? N THR A 288 O LEU A 315 ? O LEU A 295 
# 
_pdbx_entry_details.entry_id                   8S53 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 HH22 A ARG 258 ? ? O A HOH 509 ? ? 1.58 
2  1 HE   A ARG 359 ? ? O A HOH 505 ? ? 1.60 
3  1 OE2  A GLU 312 ? ? O A HOH 501 ? ? 1.85 
4  1 O    A HOH 774 ? ? O A HOH 891 ? ? 1.93 
5  1 O    A HOH 827 ? ? O A HOH 913 ? ? 2.01 
6  1 O    A HOH 501 ? ? O A HOH 628 ? ? 2.08 
7  1 NH1  A ARG 376 ? ? O A HOH 502 ? ? 2.08 
8  1 O    A HOH 587 ? ? O A HOH 736 ? ? 2.10 
9  1 O    A HOH 797 ? ? O A HOH 806 ? ? 2.11 
10 1 O    A HOH 630 ? ? O A HOH 683 ? ? 2.12 
11 1 O    A HOH 874 ? ? O A HOH 882 ? ? 2.15 
12 1 O    A HOH 802 ? ? O A HOH 841 ? ? 2.18 
13 1 O    A HOH 924 ? ? O A HOH 925 ? ? 2.18 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    HOH 
_pdbx_validate_symm_contact.auth_seq_id_1     512 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    A 
_pdbx_validate_symm_contact.auth_comp_id_2    HOH 
_pdbx_validate_symm_contact.auth_seq_id_2     868 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   3_544 
_pdbx_validate_symm_contact.dist              2.10 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_1              157 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CG 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_2              157 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             OD1 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_3              157 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                124.78 
_pdbx_validate_rmsd_angle.angle_target_value         118.30 
_pdbx_validate_rmsd_angle.angle_deviation            6.48 
_pdbx_validate_rmsd_angle.angle_standard_deviation   0.90 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLN A 31  ? ? -156.68 78.63   
2 1 LEU A 129 ? ? -130.54 -51.32  
3 1 SER A 168 ? ? -68.47  -178.58 
4 1 THR A 198 ? ? -122.38 -155.15 
5 1 ALA A 275 ? ? 28.07   69.92   
6 1 LEU A 361 ? ? -119.83 57.47   
7 1 PHE A 380 ? ? -127.21 -67.04  
8 1 MET A 387 ? ? -154.32 80.63   
9 1 MET A 387 ? ? -154.83 81.66   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
_pdbx_refine_tls.id               1 
_pdbx_refine_tls.pdbx_refine_id   'X-RAY DIFFRACTION' 
_pdbx_refine_tls.details          ? 
_pdbx_refine_tls.method           refined 
_pdbx_refine_tls.origin_x         15.2656435981 
_pdbx_refine_tls.origin_y         -11.4137079102 
_pdbx_refine_tls.origin_z         -17.5817235028 
_pdbx_refine_tls.T[1][1]          0.149856788238 
_pdbx_refine_tls.T[1][1]_esd      ? 
_pdbx_refine_tls.T[1][2]          -0.000522536466275 
_pdbx_refine_tls.T[1][2]_esd      ? 
_pdbx_refine_tls.T[1][3]          0.0120551019352 
_pdbx_refine_tls.T[1][3]_esd      ? 
_pdbx_refine_tls.T[2][2]          0.158330900138 
_pdbx_refine_tls.T[2][2]_esd      ? 
_pdbx_refine_tls.T[2][3]          0.00117760871682 
_pdbx_refine_tls.T[2][3]_esd      ? 
_pdbx_refine_tls.T[3][3]          0.111949660139 
_pdbx_refine_tls.T[3][3]_esd      ? 
_pdbx_refine_tls.L[1][1]          1.09331412997 
_pdbx_refine_tls.L[1][1]_esd      ? 
_pdbx_refine_tls.L[1][2]          -0.296788069688 
_pdbx_refine_tls.L[1][2]_esd      ? 
_pdbx_refine_tls.L[1][3]          0.388230881605 
_pdbx_refine_tls.L[1][3]_esd      ? 
_pdbx_refine_tls.L[2][2]          1.46287027988 
_pdbx_refine_tls.L[2][2]_esd      ? 
_pdbx_refine_tls.L[2][3]          -0.192030334079 
_pdbx_refine_tls.L[2][3]_esd      ? 
_pdbx_refine_tls.L[3][3]          1.17225359972 
_pdbx_refine_tls.L[3][3]_esd      ? 
_pdbx_refine_tls.S[1][1]          -0.0560713875308 
_pdbx_refine_tls.S[1][1]_esd      ? 
_pdbx_refine_tls.S[1][2]          0.0351766668585 
_pdbx_refine_tls.S[1][2]_esd      ? 
_pdbx_refine_tls.S[1][3]          0.0252162723463 
_pdbx_refine_tls.S[1][3]_esd      ? 
_pdbx_refine_tls.S[2][1]          0.0425986598878 
_pdbx_refine_tls.S[2][1]_esd      ? 
_pdbx_refine_tls.S[2][2]          0.0129613622763 
_pdbx_refine_tls.S[2][2]_esd      ? 
_pdbx_refine_tls.S[2][3]          -0.0682393401165 
_pdbx_refine_tls.S[2][3]_esd      ? 
_pdbx_refine_tls.S[3][1]          0.00280572675941 
_pdbx_refine_tls.S[3][1]_esd      ? 
_pdbx_refine_tls.S[3][2]          0.144733383601 
_pdbx_refine_tls.S[3][2]_esd      ? 
_pdbx_refine_tls.S[3][3]          0.037249297829 
_pdbx_refine_tls.S[3][3]_esd      ? 
# 
_pdbx_refine_tls_group.id                  1 
_pdbx_refine_tls_group.pdbx_refine_id      'X-RAY DIFFRACTION' 
_pdbx_refine_tls_group.refine_tls_id       1 
_pdbx_refine_tls_group.beg_label_asym_id   A 
_pdbx_refine_tls_group.beg_label_seq_id    1 
_pdbx_refine_tls_group.beg_auth_asym_id    A 
_pdbx_refine_tls_group.beg_auth_seq_id     3 
_pdbx_refine_tls_group.beg_PDB_ins_code    ? 
_pdbx_refine_tls_group.end_label_asym_id   E 
_pdbx_refine_tls_group.end_label_seq_id    ? 
_pdbx_refine_tls_group.end_auth_asym_id    S 
_pdbx_refine_tls_group.end_auth_seq_id     430 
_pdbx_refine_tls_group.end_PDB_ins_code    ? 
_pdbx_refine_tls_group.selection           ? 
_pdbx_refine_tls_group.selection_details   all 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 921 ? 5.97 . 
2 1 O ? A HOH 922 ? 6.29 . 
3 1 O ? A HOH 923 ? 6.56 . 
4 1 O ? A HOH 924 ? 6.63 . 
5 1 O ? A HOH 925 ? 6.73 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET -19 ? A MET 1   
2  1 Y 1 A GLY -18 ? A GLY 2   
3  1 Y 1 A SER -17 ? A SER 3   
4  1 Y 1 A SER -16 ? A SER 4   
5  1 Y 1 A HIS -15 ? A HIS 5   
6  1 Y 1 A HIS -14 ? A HIS 6   
7  1 Y 1 A HIS -13 ? A HIS 7   
8  1 Y 1 A HIS -12 ? A HIS 8   
9  1 Y 1 A HIS -11 ? A HIS 9   
10 1 Y 1 A HIS -10 ? A HIS 10  
11 1 Y 1 A SER -9  ? A SER 11  
12 1 Y 1 A SER -8  ? A SER 12  
13 1 Y 1 A GLY -7  ? A GLY 13  
14 1 Y 1 A LEU -6  ? A LEU 14  
15 1 Y 1 A VAL -5  ? A VAL 15  
16 1 Y 1 A PRO -4  ? A PRO 16  
17 1 Y 1 A ARG -3  ? A ARG 17  
18 1 Y 1 A GLY -2  ? A GLY 18  
19 1 Y 1 A SER -1  ? A SER 19  
20 1 Y 1 A HIS 0   ? A HIS 20  
21 1 Y 1 A MET 1   ? A MET 21  
22 1 Y 1 A THR 2   ? A THR 22  
23 1 Y 1 A GLY 398 ? A GLY 418 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
3QO CAA  C  Y N 1   
3QO CAB  C  Y N 2   
3QO CAC  C  Y N 3   
3QO CAD  C  Y N 4   
3QO CAE  C  Y N 5   
3QO CAF  C  Y N 6   
3QO CAG  C  Y N 7   
3QO CAH  C  Y N 8   
3QO CAI  C  Y N 9   
3QO CAJ  C  N N 10  
3QO NAK  N  Y N 11  
3QO CAL  C  Y N 12  
3QO CAM  C  Y N 13  
3QO HAA  H  N N 14  
3QO HAB  H  N N 15  
3QO HAC  H  N N 16  
3QO HAD  H  N N 17  
3QO HAE  H  N N 18  
3QO HAF  H  N N 19  
3QO HAG  H  N N 20  
3QO HAH  H  N N 21  
3QO HAI  H  N N 22  
3QO HAJ  H  N N 23  
3QO HAJA H  N N 24  
ALA N    N  N N 25  
ALA CA   C  N S 26  
ALA C    C  N N 27  
ALA O    O  N N 28  
ALA CB   C  N N 29  
ALA OXT  O  N N 30  
ALA H    H  N N 31  
ALA H2   H  N N 32  
ALA HA   H  N N 33  
ALA HB1  H  N N 34  
ALA HB2  H  N N 35  
ALA HB3  H  N N 36  
ALA HXT  H  N N 37  
ARG N    N  N N 38  
ARG CA   C  N S 39  
ARG C    C  N N 40  
ARG O    O  N N 41  
ARG CB   C  N N 42  
ARG CG   C  N N 43  
ARG CD   C  N N 44  
ARG NE   N  N N 45  
ARG CZ   C  N N 46  
ARG NH1  N  N N 47  
ARG NH2  N  N N 48  
ARG OXT  O  N N 49  
ARG H    H  N N 50  
ARG H2   H  N N 51  
ARG HA   H  N N 52  
ARG HB2  H  N N 53  
ARG HB3  H  N N 54  
ARG HG2  H  N N 55  
ARG HG3  H  N N 56  
ARG HD2  H  N N 57  
ARG HD3  H  N N 58  
ARG HE   H  N N 59  
ARG HH11 H  N N 60  
ARG HH12 H  N N 61  
ARG HH21 H  N N 62  
ARG HH22 H  N N 63  
ARG HXT  H  N N 64  
ASN N    N  N N 65  
ASN CA   C  N S 66  
ASN C    C  N N 67  
ASN O    O  N N 68  
ASN CB   C  N N 69  
ASN CG   C  N N 70  
ASN OD1  O  N N 71  
ASN ND2  N  N N 72  
ASN OXT  O  N N 73  
ASN H    H  N N 74  
ASN H2   H  N N 75  
ASN HA   H  N N 76  
ASN HB2  H  N N 77  
ASN HB3  H  N N 78  
ASN HD21 H  N N 79  
ASN HD22 H  N N 80  
ASN HXT  H  N N 81  
ASP N    N  N N 82  
ASP CA   C  N S 83  
ASP C    C  N N 84  
ASP O    O  N N 85  
ASP CB   C  N N 86  
ASP CG   C  N N 87  
ASP OD1  O  N N 88  
ASP OD2  O  N N 89  
ASP OXT  O  N N 90  
ASP H    H  N N 91  
ASP H2   H  N N 92  
ASP HA   H  N N 93  
ASP HB2  H  N N 94  
ASP HB3  H  N N 95  
ASP HD2  H  N N 96  
ASP HXT  H  N N 97  
CYS N    N  N N 98  
CYS CA   C  N R 99  
CYS C    C  N N 100 
CYS O    O  N N 101 
CYS CB   C  N N 102 
CYS SG   S  N N 103 
CYS OXT  O  N N 104 
CYS H    H  N N 105 
CYS H2   H  N N 106 
CYS HA   H  N N 107 
CYS HB2  H  N N 108 
CYS HB3  H  N N 109 
CYS HG   H  N N 110 
CYS HXT  H  N N 111 
GLN N    N  N N 112 
GLN CA   C  N S 113 
GLN C    C  N N 114 
GLN O    O  N N 115 
GLN CB   C  N N 116 
GLN CG   C  N N 117 
GLN CD   C  N N 118 
GLN OE1  O  N N 119 
GLN NE2  N  N N 120 
GLN OXT  O  N N 121 
GLN H    H  N N 122 
GLN H2   H  N N 123 
GLN HA   H  N N 124 
GLN HB2  H  N N 125 
GLN HB3  H  N N 126 
GLN HG2  H  N N 127 
GLN HG3  H  N N 128 
GLN HE21 H  N N 129 
GLN HE22 H  N N 130 
GLN HXT  H  N N 131 
GLU N    N  N N 132 
GLU CA   C  N S 133 
GLU C    C  N N 134 
GLU O    O  N N 135 
GLU CB   C  N N 136 
GLU CG   C  N N 137 
GLU CD   C  N N 138 
GLU OE1  O  N N 139 
GLU OE2  O  N N 140 
GLU OXT  O  N N 141 
GLU H    H  N N 142 
GLU H2   H  N N 143 
GLU HA   H  N N 144 
GLU HB2  H  N N 145 
GLU HB3  H  N N 146 
GLU HG2  H  N N 147 
GLU HG3  H  N N 148 
GLU HE2  H  N N 149 
GLU HXT  H  N N 150 
GLY N    N  N N 151 
GLY CA   C  N N 152 
GLY C    C  N N 153 
GLY O    O  N N 154 
GLY OXT  O  N N 155 
GLY H    H  N N 156 
GLY H2   H  N N 157 
GLY HA2  H  N N 158 
GLY HA3  H  N N 159 
GLY HXT  H  N N 160 
HEM CHA  C  N N 161 
HEM CHB  C  N N 162 
HEM CHC  C  N N 163 
HEM CHD  C  N N 164 
HEM C1A  C  Y N 165 
HEM C2A  C  Y N 166 
HEM C3A  C  Y N 167 
HEM C4A  C  Y N 168 
HEM CMA  C  N N 169 
HEM CAA  C  N N 170 
HEM CBA  C  N N 171 
HEM CGA  C  N N 172 
HEM O1A  O  N N 173 
HEM O2A  O  N N 174 
HEM C1B  C  N N 175 
HEM C2B  C  N N 176 
HEM C3B  C  N N 177 
HEM C4B  C  N N 178 
HEM CMB  C  N N 179 
HEM CAB  C  N N 180 
HEM CBB  C  N N 181 
HEM C1C  C  Y N 182 
HEM C2C  C  Y N 183 
HEM C3C  C  Y N 184 
HEM C4C  C  Y N 185 
HEM CMC  C  N N 186 
HEM CAC  C  N N 187 
HEM CBC  C  N N 188 
HEM C1D  C  N N 189 
HEM C2D  C  N N 190 
HEM C3D  C  N N 191 
HEM C4D  C  N N 192 
HEM CMD  C  N N 193 
HEM CAD  C  N N 194 
HEM CBD  C  N N 195 
HEM CGD  C  N N 196 
HEM O1D  O  N N 197 
HEM O2D  O  N N 198 
HEM NA   N  Y N 199 
HEM NB   N  N N 200 
HEM NC   N  Y N 201 
HEM ND   N  N N 202 
HEM FE   FE N N 203 
HEM HHB  H  N N 204 
HEM HHC  H  N N 205 
HEM HHD  H  N N 206 
HEM HMA  H  N N 207 
HEM HMAA H  N N 208 
HEM HMAB H  N N 209 
HEM HAA  H  N N 210 
HEM HAAA H  N N 211 
HEM HBA  H  N N 212 
HEM HBAA H  N N 213 
HEM HMB  H  N N 214 
HEM HMBA H  N N 215 
HEM HMBB H  N N 216 
HEM HAB  H  N N 217 
HEM HBB  H  N N 218 
HEM HBBA H  N N 219 
HEM HMC  H  N N 220 
HEM HMCA H  N N 221 
HEM HMCB H  N N 222 
HEM HAC  H  N N 223 
HEM HBC  H  N N 224 
HEM HBCA H  N N 225 
HEM HMD  H  N N 226 
HEM HMDA H  N N 227 
HEM HMDB H  N N 228 
HEM HAD  H  N N 229 
HEM HADA H  N N 230 
HEM HBD  H  N N 231 
HEM HBDA H  N N 232 
HEM H2A  H  N N 233 
HEM H2D  H  N N 234 
HEM HHA  H  N N 235 
HIS N    N  N N 236 
HIS CA   C  N S 237 
HIS C    C  N N 238 
HIS O    O  N N 239 
HIS CB   C  N N 240 
HIS CG   C  Y N 241 
HIS ND1  N  Y N 242 
HIS CD2  C  Y N 243 
HIS CE1  C  Y N 244 
HIS NE2  N  Y N 245 
HIS OXT  O  N N 246 
HIS H    H  N N 247 
HIS H2   H  N N 248 
HIS HA   H  N N 249 
HIS HB2  H  N N 250 
HIS HB3  H  N N 251 
HIS HD1  H  N N 252 
HIS HD2  H  N N 253 
HIS HE1  H  N N 254 
HIS HE2  H  N N 255 
HIS HXT  H  N N 256 
HOH O    O  N N 257 
HOH H1   H  N N 258 
HOH H2   H  N N 259 
ILE N    N  N N 260 
ILE CA   C  N S 261 
ILE C    C  N N 262 
ILE O    O  N N 263 
ILE CB   C  N S 264 
ILE CG1  C  N N 265 
ILE CG2  C  N N 266 
ILE CD1  C  N N 267 
ILE OXT  O  N N 268 
ILE H    H  N N 269 
ILE H2   H  N N 270 
ILE HA   H  N N 271 
ILE HB   H  N N 272 
ILE HG12 H  N N 273 
ILE HG13 H  N N 274 
ILE HG21 H  N N 275 
ILE HG22 H  N N 276 
ILE HG23 H  N N 277 
ILE HD11 H  N N 278 
ILE HD12 H  N N 279 
ILE HD13 H  N N 280 
ILE HXT  H  N N 281 
LEU N    N  N N 282 
LEU CA   C  N S 283 
LEU C    C  N N 284 
LEU O    O  N N 285 
LEU CB   C  N N 286 
LEU CG   C  N N 287 
LEU CD1  C  N N 288 
LEU CD2  C  N N 289 
LEU OXT  O  N N 290 
LEU H    H  N N 291 
LEU H2   H  N N 292 
LEU HA   H  N N 293 
LEU HB2  H  N N 294 
LEU HB3  H  N N 295 
LEU HG   H  N N 296 
LEU HD11 H  N N 297 
LEU HD12 H  N N 298 
LEU HD13 H  N N 299 
LEU HD21 H  N N 300 
LEU HD22 H  N N 301 
LEU HD23 H  N N 302 
LEU HXT  H  N N 303 
LYS N    N  N N 304 
LYS CA   C  N S 305 
LYS C    C  N N 306 
LYS O    O  N N 307 
LYS CB   C  N N 308 
LYS CG   C  N N 309 
LYS CD   C  N N 310 
LYS CE   C  N N 311 
LYS NZ   N  N N 312 
LYS OXT  O  N N 313 
LYS H    H  N N 314 
LYS H2   H  N N 315 
LYS HA   H  N N 316 
LYS HB2  H  N N 317 
LYS HB3  H  N N 318 
LYS HG2  H  N N 319 
LYS HG3  H  N N 320 
LYS HD2  H  N N 321 
LYS HD3  H  N N 322 
LYS HE2  H  N N 323 
LYS HE3  H  N N 324 
LYS HZ1  H  N N 325 
LYS HZ2  H  N N 326 
LYS HZ3  H  N N 327 
LYS HXT  H  N N 328 
MET N    N  N N 329 
MET CA   C  N S 330 
MET C    C  N N 331 
MET O    O  N N 332 
MET CB   C  N N 333 
MET CG   C  N N 334 
MET SD   S  N N 335 
MET CE   C  N N 336 
MET OXT  O  N N 337 
MET H    H  N N 338 
MET H2   H  N N 339 
MET HA   H  N N 340 
MET HB2  H  N N 341 
MET HB3  H  N N 342 
MET HG2  H  N N 343 
MET HG3  H  N N 344 
MET HE1  H  N N 345 
MET HE2  H  N N 346 
MET HE3  H  N N 347 
MET HXT  H  N N 348 
PHE N    N  N N 349 
PHE CA   C  N S 350 
PHE C    C  N N 351 
PHE O    O  N N 352 
PHE CB   C  N N 353 
PHE CG   C  Y N 354 
PHE CD1  C  Y N 355 
PHE CD2  C  Y N 356 
PHE CE1  C  Y N 357 
PHE CE2  C  Y N 358 
PHE CZ   C  Y N 359 
PHE OXT  O  N N 360 
PHE H    H  N N 361 
PHE H2   H  N N 362 
PHE HA   H  N N 363 
PHE HB2  H  N N 364 
PHE HB3  H  N N 365 
PHE HD1  H  N N 366 
PHE HD2  H  N N 367 
PHE HE1  H  N N 368 
PHE HE2  H  N N 369 
PHE HZ   H  N N 370 
PHE HXT  H  N N 371 
PRO N    N  N N 372 
PRO CA   C  N S 373 
PRO C    C  N N 374 
PRO O    O  N N 375 
PRO CB   C  N N 376 
PRO CG   C  N N 377 
PRO CD   C  N N 378 
PRO OXT  O  N N 379 
PRO H    H  N N 380 
PRO HA   H  N N 381 
PRO HB2  H  N N 382 
PRO HB3  H  N N 383 
PRO HG2  H  N N 384 
PRO HG3  H  N N 385 
PRO HD2  H  N N 386 
PRO HD3  H  N N 387 
PRO HXT  H  N N 388 
SER N    N  N N 389 
SER CA   C  N S 390 
SER C    C  N N 391 
SER O    O  N N 392 
SER CB   C  N N 393 
SER OG   O  N N 394 
SER OXT  O  N N 395 
SER H    H  N N 396 
SER H2   H  N N 397 
SER HA   H  N N 398 
SER HB2  H  N N 399 
SER HB3  H  N N 400 
SER HG   H  N N 401 
SER HXT  H  N N 402 
THR N    N  N N 403 
THR CA   C  N S 404 
THR C    C  N N 405 
THR O    O  N N 406 
THR CB   C  N R 407 
THR OG1  O  N N 408 
THR CG2  C  N N 409 
THR OXT  O  N N 410 
THR H    H  N N 411 
THR H2   H  N N 412 
THR HA   H  N N 413 
THR HB   H  N N 414 
THR HG1  H  N N 415 
THR HG21 H  N N 416 
THR HG22 H  N N 417 
THR HG23 H  N N 418 
THR HXT  H  N N 419 
TRP N    N  N N 420 
TRP CA   C  N S 421 
TRP C    C  N N 422 
TRP O    O  N N 423 
TRP CB   C  N N 424 
TRP CG   C  Y N 425 
TRP CD1  C  Y N 426 
TRP CD2  C  Y N 427 
TRP NE1  N  Y N 428 
TRP CE2  C  Y N 429 
TRP CE3  C  Y N 430 
TRP CZ2  C  Y N 431 
TRP CZ3  C  Y N 432 
TRP CH2  C  Y N 433 
TRP OXT  O  N N 434 
TRP H    H  N N 435 
TRP H2   H  N N 436 
TRP HA   H  N N 437 
TRP HB2  H  N N 438 
TRP HB3  H  N N 439 
TRP HD1  H  N N 440 
TRP HE1  H  N N 441 
TRP HE3  H  N N 442 
TRP HZ2  H  N N 443 
TRP HZ3  H  N N 444 
TRP HH2  H  N N 445 
TRP HXT  H  N N 446 
TYR N    N  N N 447 
TYR CA   C  N S 448 
TYR C    C  N N 449 
TYR O    O  N N 450 
TYR CB   C  N N 451 
TYR CG   C  Y N 452 
TYR CD1  C  Y N 453 
TYR CD2  C  Y N 454 
TYR CE1  C  Y N 455 
TYR CE2  C  Y N 456 
TYR CZ   C  Y N 457 
TYR OH   O  N N 458 
TYR OXT  O  N N 459 
TYR H    H  N N 460 
TYR H2   H  N N 461 
TYR HA   H  N N 462 
TYR HB2  H  N N 463 
TYR HB3  H  N N 464 
TYR HD1  H  N N 465 
TYR HD2  H  N N 466 
TYR HE1  H  N N 467 
TYR HE2  H  N N 468 
TYR HH   H  N N 469 
TYR HXT  H  N N 470 
VAL N    N  N N 471 
VAL CA   C  N S 472 
VAL C    C  N N 473 
VAL O    O  N N 474 
VAL CB   C  N N 475 
VAL CG1  C  N N 476 
VAL CG2  C  N N 477 
VAL OXT  O  N N 478 
VAL H    H  N N 479 
VAL H2   H  N N 480 
VAL HA   H  N N 481 
VAL HB   H  N N 482 
VAL HG11 H  N N 483 
VAL HG12 H  N N 484 
VAL HG13 H  N N 485 
VAL HG21 H  N N 486 
VAL HG22 H  N N 487 
VAL HG23 H  N N 488 
VAL HXT  H  N N 489 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
3QO CAB CAA  doub Y N 1   
3QO CAA CAC  sing Y N 2   
3QO CAA HAA  sing N N 3   
3QO CAB CAF  sing Y N 4   
3QO CAB HAB  sing N N 5   
3QO CAC CAG  doub Y N 6   
3QO CAC HAC  sing N N 7   
3QO CAH CAD  doub Y N 8   
3QO CAD NAK  sing Y N 9   
3QO CAD HAD  sing N N 10  
3QO CAI CAE  sing Y N 11  
3QO NAK CAE  doub Y N 12  
3QO CAE HAE  sing N N 13  
3QO CAF CAL  doub Y N 14  
3QO CAF HAF  sing N N 15  
3QO CAL CAG  sing Y N 16  
3QO CAG HAG  sing N N 17  
3QO CAH CAM  sing Y N 18  
3QO CAH HAH  sing N N 19  
3QO CAM CAI  doub Y N 20  
3QO CAI HAI  sing N N 21  
3QO CAL CAJ  sing N N 22  
3QO CAJ CAM  sing N N 23  
3QO CAJ HAJ  sing N N 24  
3QO CAJ HAJA sing N N 25  
ALA N   CA   sing N N 26  
ALA N   H    sing N N 27  
ALA N   H2   sing N N 28  
ALA CA  C    sing N N 29  
ALA CA  CB   sing N N 30  
ALA CA  HA   sing N N 31  
ALA C   O    doub N N 32  
ALA C   OXT  sing N N 33  
ALA CB  HB1  sing N N 34  
ALA CB  HB2  sing N N 35  
ALA CB  HB3  sing N N 36  
ALA OXT HXT  sing N N 37  
ARG N   CA   sing N N 38  
ARG N   H    sing N N 39  
ARG N   H2   sing N N 40  
ARG CA  C    sing N N 41  
ARG CA  CB   sing N N 42  
ARG CA  HA   sing N N 43  
ARG C   O    doub N N 44  
ARG C   OXT  sing N N 45  
ARG CB  CG   sing N N 46  
ARG CB  HB2  sing N N 47  
ARG CB  HB3  sing N N 48  
ARG CG  CD   sing N N 49  
ARG CG  HG2  sing N N 50  
ARG CG  HG3  sing N N 51  
ARG CD  NE   sing N N 52  
ARG CD  HD2  sing N N 53  
ARG CD  HD3  sing N N 54  
ARG NE  CZ   sing N N 55  
ARG NE  HE   sing N N 56  
ARG CZ  NH1  sing N N 57  
ARG CZ  NH2  doub N N 58  
ARG NH1 HH11 sing N N 59  
ARG NH1 HH12 sing N N 60  
ARG NH2 HH21 sing N N 61  
ARG NH2 HH22 sing N N 62  
ARG OXT HXT  sing N N 63  
ASN N   CA   sing N N 64  
ASN N   H    sing N N 65  
ASN N   H2   sing N N 66  
ASN CA  C    sing N N 67  
ASN CA  CB   sing N N 68  
ASN CA  HA   sing N N 69  
ASN C   O    doub N N 70  
ASN C   OXT  sing N N 71  
ASN CB  CG   sing N N 72  
ASN CB  HB2  sing N N 73  
ASN CB  HB3  sing N N 74  
ASN CG  OD1  doub N N 75  
ASN CG  ND2  sing N N 76  
ASN ND2 HD21 sing N N 77  
ASN ND2 HD22 sing N N 78  
ASN OXT HXT  sing N N 79  
ASP N   CA   sing N N 80  
ASP N   H    sing N N 81  
ASP N   H2   sing N N 82  
ASP CA  C    sing N N 83  
ASP CA  CB   sing N N 84  
ASP CA  HA   sing N N 85  
ASP C   O    doub N N 86  
ASP C   OXT  sing N N 87  
ASP CB  CG   sing N N 88  
ASP CB  HB2  sing N N 89  
ASP CB  HB3  sing N N 90  
ASP CG  OD1  doub N N 91  
ASP CG  OD2  sing N N 92  
ASP OD2 HD2  sing N N 93  
ASP OXT HXT  sing N N 94  
CYS N   CA   sing N N 95  
CYS N   H    sing N N 96  
CYS N   H2   sing N N 97  
CYS CA  C    sing N N 98  
CYS CA  CB   sing N N 99  
CYS CA  HA   sing N N 100 
CYS C   O    doub N N 101 
CYS C   OXT  sing N N 102 
CYS CB  SG   sing N N 103 
CYS CB  HB2  sing N N 104 
CYS CB  HB3  sing N N 105 
CYS SG  HG   sing N N 106 
CYS OXT HXT  sing N N 107 
GLN N   CA   sing N N 108 
GLN N   H    sing N N 109 
GLN N   H2   sing N N 110 
GLN CA  C    sing N N 111 
GLN CA  CB   sing N N 112 
GLN CA  HA   sing N N 113 
GLN C   O    doub N N 114 
GLN C   OXT  sing N N 115 
GLN CB  CG   sing N N 116 
GLN CB  HB2  sing N N 117 
GLN CB  HB3  sing N N 118 
GLN CG  CD   sing N N 119 
GLN CG  HG2  sing N N 120 
GLN CG  HG3  sing N N 121 
GLN CD  OE1  doub N N 122 
GLN CD  NE2  sing N N 123 
GLN NE2 HE21 sing N N 124 
GLN NE2 HE22 sing N N 125 
GLN OXT HXT  sing N N 126 
GLU N   CA   sing N N 127 
GLU N   H    sing N N 128 
GLU N   H2   sing N N 129 
GLU CA  C    sing N N 130 
GLU CA  CB   sing N N 131 
GLU CA  HA   sing N N 132 
GLU C   O    doub N N 133 
GLU C   OXT  sing N N 134 
GLU CB  CG   sing N N 135 
GLU CB  HB2  sing N N 136 
GLU CB  HB3  sing N N 137 
GLU CG  CD   sing N N 138 
GLU CG  HG2  sing N N 139 
GLU CG  HG3  sing N N 140 
GLU CD  OE1  doub N N 141 
GLU CD  OE2  sing N N 142 
GLU OE2 HE2  sing N N 143 
GLU OXT HXT  sing N N 144 
GLY N   CA   sing N N 145 
GLY N   H    sing N N 146 
GLY N   H2   sing N N 147 
GLY CA  C    sing N N 148 
GLY CA  HA2  sing N N 149 
GLY CA  HA3  sing N N 150 
GLY C   O    doub N N 151 
GLY C   OXT  sing N N 152 
GLY OXT HXT  sing N N 153 
HEM CHA C1A  sing N N 154 
HEM CHA C4D  doub N N 155 
HEM CHA HHA  sing N N 156 
HEM CHB C4A  sing N N 157 
HEM CHB C1B  doub N N 158 
HEM CHB HHB  sing N N 159 
HEM CHC C4B  sing N N 160 
HEM CHC C1C  doub N N 161 
HEM CHC HHC  sing N N 162 
HEM CHD C4C  doub N N 163 
HEM CHD C1D  sing N N 164 
HEM CHD HHD  sing N N 165 
HEM C1A C2A  doub Y N 166 
HEM C1A NA   sing Y N 167 
HEM C2A C3A  sing Y N 168 
HEM C2A CAA  sing N N 169 
HEM C3A C4A  doub Y N 170 
HEM C3A CMA  sing N N 171 
HEM C4A NA   sing Y N 172 
HEM CMA HMA  sing N N 173 
HEM CMA HMAA sing N N 174 
HEM CMA HMAB sing N N 175 
HEM CAA CBA  sing N N 176 
HEM CAA HAA  sing N N 177 
HEM CAA HAAA sing N N 178 
HEM CBA CGA  sing N N 179 
HEM CBA HBA  sing N N 180 
HEM CBA HBAA sing N N 181 
HEM CGA O1A  doub N N 182 
HEM CGA O2A  sing N N 183 
HEM C1B C2B  sing N N 184 
HEM C1B NB   sing N N 185 
HEM C2B C3B  doub N N 186 
HEM C2B CMB  sing N N 187 
HEM C3B C4B  sing N N 188 
HEM C3B CAB  sing N N 189 
HEM C4B NB   doub N N 190 
HEM CMB HMB  sing N N 191 
HEM CMB HMBA sing N N 192 
HEM CMB HMBB sing N N 193 
HEM CAB CBB  doub N N 194 
HEM CAB HAB  sing N N 195 
HEM CBB HBB  sing N N 196 
HEM CBB HBBA sing N N 197 
HEM C1C C2C  sing Y N 198 
HEM C1C NC   sing Y N 199 
HEM C2C C3C  doub Y N 200 
HEM C2C CMC  sing N N 201 
HEM C3C C4C  sing Y N 202 
HEM C3C CAC  sing N N 203 
HEM C4C NC   sing Y N 204 
HEM CMC HMC  sing N N 205 
HEM CMC HMCA sing N N 206 
HEM CMC HMCB sing N N 207 
HEM CAC CBC  doub N N 208 
HEM CAC HAC  sing N N 209 
HEM CBC HBC  sing N N 210 
HEM CBC HBCA sing N N 211 
HEM C1D C2D  sing N N 212 
HEM C1D ND   doub N N 213 
HEM C2D C3D  doub N N 214 
HEM C2D CMD  sing N N 215 
HEM C3D C4D  sing N N 216 
HEM C3D CAD  sing N N 217 
HEM C4D ND   sing N N 218 
HEM CMD HMD  sing N N 219 
HEM CMD HMDA sing N N 220 
HEM CMD HMDB sing N N 221 
HEM CAD CBD  sing N N 222 
HEM CAD HAD  sing N N 223 
HEM CAD HADA sing N N 224 
HEM CBD CGD  sing N N 225 
HEM CBD HBD  sing N N 226 
HEM CBD HBDA sing N N 227 
HEM CGD O1D  doub N N 228 
HEM CGD O2D  sing N N 229 
HEM O2A H2A  sing N N 230 
HEM O2D H2D  sing N N 231 
HEM FE  NA   sing N N 232 
HEM FE  NB   sing N N 233 
HEM FE  NC   sing N N 234 
HEM FE  ND   sing N N 235 
HIS N   CA   sing N N 236 
HIS N   H    sing N N 237 
HIS N   H2   sing N N 238 
HIS CA  C    sing N N 239 
HIS CA  CB   sing N N 240 
HIS CA  HA   sing N N 241 
HIS C   O    doub N N 242 
HIS C   OXT  sing N N 243 
HIS CB  CG   sing N N 244 
HIS CB  HB2  sing N N 245 
HIS CB  HB3  sing N N 246 
HIS CG  ND1  sing Y N 247 
HIS CG  CD2  doub Y N 248 
HIS ND1 CE1  doub Y N 249 
HIS ND1 HD1  sing N N 250 
HIS CD2 NE2  sing Y N 251 
HIS CD2 HD2  sing N N 252 
HIS CE1 NE2  sing Y N 253 
HIS CE1 HE1  sing N N 254 
HIS NE2 HE2  sing N N 255 
HIS OXT HXT  sing N N 256 
HOH O   H1   sing N N 257 
HOH O   H2   sing N N 258 
ILE N   CA   sing N N 259 
ILE N   H    sing N N 260 
ILE N   H2   sing N N 261 
ILE CA  C    sing N N 262 
ILE CA  CB   sing N N 263 
ILE CA  HA   sing N N 264 
ILE C   O    doub N N 265 
ILE C   OXT  sing N N 266 
ILE CB  CG1  sing N N 267 
ILE CB  CG2  sing N N 268 
ILE CB  HB   sing N N 269 
ILE CG1 CD1  sing N N 270 
ILE CG1 HG12 sing N N 271 
ILE CG1 HG13 sing N N 272 
ILE CG2 HG21 sing N N 273 
ILE CG2 HG22 sing N N 274 
ILE CG2 HG23 sing N N 275 
ILE CD1 HD11 sing N N 276 
ILE CD1 HD12 sing N N 277 
ILE CD1 HD13 sing N N 278 
ILE OXT HXT  sing N N 279 
LEU N   CA   sing N N 280 
LEU N   H    sing N N 281 
LEU N   H2   sing N N 282 
LEU CA  C    sing N N 283 
LEU CA  CB   sing N N 284 
LEU CA  HA   sing N N 285 
LEU C   O    doub N N 286 
LEU C   OXT  sing N N 287 
LEU CB  CG   sing N N 288 
LEU CB  HB2  sing N N 289 
LEU CB  HB3  sing N N 290 
LEU CG  CD1  sing N N 291 
LEU CG  CD2  sing N N 292 
LEU CG  HG   sing N N 293 
LEU CD1 HD11 sing N N 294 
LEU CD1 HD12 sing N N 295 
LEU CD1 HD13 sing N N 296 
LEU CD2 HD21 sing N N 297 
LEU CD2 HD22 sing N N 298 
LEU CD2 HD23 sing N N 299 
LEU OXT HXT  sing N N 300 
LYS N   CA   sing N N 301 
LYS N   H    sing N N 302 
LYS N   H2   sing N N 303 
LYS CA  C    sing N N 304 
LYS CA  CB   sing N N 305 
LYS CA  HA   sing N N 306 
LYS C   O    doub N N 307 
LYS C   OXT  sing N N 308 
LYS CB  CG   sing N N 309 
LYS CB  HB2  sing N N 310 
LYS CB  HB3  sing N N 311 
LYS CG  CD   sing N N 312 
LYS CG  HG2  sing N N 313 
LYS CG  HG3  sing N N 314 
LYS CD  CE   sing N N 315 
LYS CD  HD2  sing N N 316 
LYS CD  HD3  sing N N 317 
LYS CE  NZ   sing N N 318 
LYS CE  HE2  sing N N 319 
LYS CE  HE3  sing N N 320 
LYS NZ  HZ1  sing N N 321 
LYS NZ  HZ2  sing N N 322 
LYS NZ  HZ3  sing N N 323 
LYS OXT HXT  sing N N 324 
MET N   CA   sing N N 325 
MET N   H    sing N N 326 
MET N   H2   sing N N 327 
MET CA  C    sing N N 328 
MET CA  CB   sing N N 329 
MET CA  HA   sing N N 330 
MET C   O    doub N N 331 
MET C   OXT  sing N N 332 
MET CB  CG   sing N N 333 
MET CB  HB2  sing N N 334 
MET CB  HB3  sing N N 335 
MET CG  SD   sing N N 336 
MET CG  HG2  sing N N 337 
MET CG  HG3  sing N N 338 
MET SD  CE   sing N N 339 
MET CE  HE1  sing N N 340 
MET CE  HE2  sing N N 341 
MET CE  HE3  sing N N 342 
MET OXT HXT  sing N N 343 
PHE N   CA   sing N N 344 
PHE N   H    sing N N 345 
PHE N   H2   sing N N 346 
PHE CA  C    sing N N 347 
PHE CA  CB   sing N N 348 
PHE CA  HA   sing N N 349 
PHE C   O    doub N N 350 
PHE C   OXT  sing N N 351 
PHE CB  CG   sing N N 352 
PHE CB  HB2  sing N N 353 
PHE CB  HB3  sing N N 354 
PHE CG  CD1  doub Y N 355 
PHE CG  CD2  sing Y N 356 
PHE CD1 CE1  sing Y N 357 
PHE CD1 HD1  sing N N 358 
PHE CD2 CE2  doub Y N 359 
PHE CD2 HD2  sing N N 360 
PHE CE1 CZ   doub Y N 361 
PHE CE1 HE1  sing N N 362 
PHE CE2 CZ   sing Y N 363 
PHE CE2 HE2  sing N N 364 
PHE CZ  HZ   sing N N 365 
PHE OXT HXT  sing N N 366 
PRO N   CA   sing N N 367 
PRO N   CD   sing N N 368 
PRO N   H    sing N N 369 
PRO CA  C    sing N N 370 
PRO CA  CB   sing N N 371 
PRO CA  HA   sing N N 372 
PRO C   O    doub N N 373 
PRO C   OXT  sing N N 374 
PRO CB  CG   sing N N 375 
PRO CB  HB2  sing N N 376 
PRO CB  HB3  sing N N 377 
PRO CG  CD   sing N N 378 
PRO CG  HG2  sing N N 379 
PRO CG  HG3  sing N N 380 
PRO CD  HD2  sing N N 381 
PRO CD  HD3  sing N N 382 
PRO OXT HXT  sing N N 383 
SER N   CA   sing N N 384 
SER N   H    sing N N 385 
SER N   H2   sing N N 386 
SER CA  C    sing N N 387 
SER CA  CB   sing N N 388 
SER CA  HA   sing N N 389 
SER C   O    doub N N 390 
SER C   OXT  sing N N 391 
SER CB  OG   sing N N 392 
SER CB  HB2  sing N N 393 
SER CB  HB3  sing N N 394 
SER OG  HG   sing N N 395 
SER OXT HXT  sing N N 396 
THR N   CA   sing N N 397 
THR N   H    sing N N 398 
THR N   H2   sing N N 399 
THR CA  C    sing N N 400 
THR CA  CB   sing N N 401 
THR CA  HA   sing N N 402 
THR C   O    doub N N 403 
THR C   OXT  sing N N 404 
THR CB  OG1  sing N N 405 
THR CB  CG2  sing N N 406 
THR CB  HB   sing N N 407 
THR OG1 HG1  sing N N 408 
THR CG2 HG21 sing N N 409 
THR CG2 HG22 sing N N 410 
THR CG2 HG23 sing N N 411 
THR OXT HXT  sing N N 412 
TRP N   CA   sing N N 413 
TRP N   H    sing N N 414 
TRP N   H2   sing N N 415 
TRP CA  C    sing N N 416 
TRP CA  CB   sing N N 417 
TRP CA  HA   sing N N 418 
TRP C   O    doub N N 419 
TRP C   OXT  sing N N 420 
TRP CB  CG   sing N N 421 
TRP CB  HB2  sing N N 422 
TRP CB  HB3  sing N N 423 
TRP CG  CD1  doub Y N 424 
TRP CG  CD2  sing Y N 425 
TRP CD1 NE1  sing Y N 426 
TRP CD1 HD1  sing N N 427 
TRP CD2 CE2  doub Y N 428 
TRP CD2 CE3  sing Y N 429 
TRP NE1 CE2  sing Y N 430 
TRP NE1 HE1  sing N N 431 
TRP CE2 CZ2  sing Y N 432 
TRP CE3 CZ3  doub Y N 433 
TRP CE3 HE3  sing N N 434 
TRP CZ2 CH2  doub Y N 435 
TRP CZ2 HZ2  sing N N 436 
TRP CZ3 CH2  sing Y N 437 
TRP CZ3 HZ3  sing N N 438 
TRP CH2 HH2  sing N N 439 
TRP OXT HXT  sing N N 440 
TYR N   CA   sing N N 441 
TYR N   H    sing N N 442 
TYR N   H2   sing N N 443 
TYR CA  C    sing N N 444 
TYR CA  CB   sing N N 445 
TYR CA  HA   sing N N 446 
TYR C   O    doub N N 447 
TYR C   OXT  sing N N 448 
TYR CB  CG   sing N N 449 
TYR CB  HB2  sing N N 450 
TYR CB  HB3  sing N N 451 
TYR CG  CD1  doub Y N 452 
TYR CG  CD2  sing Y N 453 
TYR CD1 CE1  sing Y N 454 
TYR CD1 HD1  sing N N 455 
TYR CD2 CE2  doub Y N 456 
TYR CD2 HD2  sing N N 457 
TYR CE1 CZ   doub Y N 458 
TYR CE1 HE1  sing N N 459 
TYR CE2 CZ   sing Y N 460 
TYR CE2 HE2  sing N N 461 
TYR CZ  OH   sing N N 462 
TYR OH  HH   sing N N 463 
TYR OXT HXT  sing N N 464 
VAL N   CA   sing N N 465 
VAL N   H    sing N N 466 
VAL N   H2   sing N N 467 
VAL CA  C    sing N N 468 
VAL CA  CB   sing N N 469 
VAL CA  HA   sing N N 470 
VAL C   O    doub N N 471 
VAL C   OXT  sing N N 472 
VAL CB  CG1  sing N N 473 
VAL CB  CG2  sing N N 474 
VAL CB  HB   sing N N 475 
VAL CG1 HG11 sing N N 476 
VAL CG1 HG12 sing N N 477 
VAL CG1 HG13 sing N N 478 
VAL CG2 HG21 sing N N 479 
VAL CG2 HG22 sing N N 480 
VAL CG2 HG23 sing N N 481 
VAL OXT HXT  sing N N 482 
# 
_pdbx_audit_support.funding_organization   'Biotechnology and Biological Sciences Research Council (BBSRC)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2XKR 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8S53 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.018032 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015204 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007654 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
FE ? ? 20.90327 4.99816 ? ? 2.55100  38.46870 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345  0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . GLU A 1 23  ? -12.96001 4.98636   -20.17782 1.000 48.53566  ? 3   GLU A N    1 
ATOM   2    C  CA   . GLU A 1 23  ? -11.91051 5.89900   -19.71307 1.000 49.21991  ? 3   GLU A CA   1 
ATOM   3    C  C    . GLU A 1 23  ? -10.59535 5.14810   -19.44511 1.000 45.77351  ? 3   GLU A C    1 
ATOM   4    O  O    . GLU A 1 23  ? -10.60196 3.95061   -19.22703 1.000 43.50075  ? 3   GLU A O    1 
ATOM   5    C  CB   . GLU A 1 23  ? -12.35694 6.62505   -18.44987 1.000 51.16064  ? 3   GLU A CB   1 
ATOM   6    C  CG   . GLU A 1 23  ? -11.32826 7.62045   -17.93940 1.000 69.55452  ? 3   GLU A CG   1 
ATOM   7    C  CD   . GLU A 1 23  ? -10.88200 8.60690   -19.01325 1.000 75.90392  ? 3   GLU A CD   1 
ATOM   8    O  OE1  . GLU A 1 23  ? -11.64075 8.82911   -19.98401 1.000 79.27823  ? 3   GLU A OE1  1 
ATOM   9    O  OE2  . GLU A 1 23  ? -9.75289  9.13048   -18.90206 1.000 71.41067  ? 3   GLU A OE2  1 
ATOM   10   H  HA   . GLU A 1 23  ? -11.74406 6.55962   -20.40356 1.000 59.08765  ? 3   GLU A HA   1 
ATOM   11   N  N    . ALA A 1 24  ? -9.47316  5.86476   -19.43635 1.000 39.89129  ? 4   ALA A N    1 
ATOM   12   C  CA   . ALA A 1 24  ? -8.16918  5.20710   -19.32032 1.000 38.54379  ? 4   ALA A CA   1 
ATOM   13   C  C    . ALA A 1 24  ? -8.00890  4.53379   -17.95406 1.000 37.35291  ? 4   ALA A C    1 
ATOM   14   O  O    . ALA A 1 24  ? -8.54215  5.00109   -16.94766 1.000 39.52611  ? 4   ALA A O    1 
ATOM   15   C  CB   . ALA A 1 24  ? -7.03795  6.21353   -19.51025 1.000 38.26672  ? 4   ALA A CB   1 
ATOM   16   H  H    . ALA A 1 24  ? -9.43716  6.72198   -19.49531 1.000 47.89332  ? 4   ALA A H    1 
ATOM   17   H  HA   . ALA A 1 24  ? -8.10538  4.52649   -20.00850 1.000 46.27631  ? 4   ALA A HA   1 
ATOM   18   H  HB1  . ALA A 1 24  ? -6.18836  5.75120   -19.43720 1.000 45.94383  ? 4   ALA A HB1  1 
ATOM   19   H  HB2  . ALA A 1 24  ? -7.11971  6.61864   -20.38780 1.000 45.94383  ? 4   ALA A HB2  1 
ATOM   20   H  HB3  . ALA A 1 24  ? -7.10348  6.89558   -18.82366 1.000 45.94383  ? 4   ALA A HB3  1 
ATOM   21   N  N    . PRO A 1 25  ? -7.26297  3.44048   -17.88420 1.000 38.70942  ? 5   PRO A N    1 
ATOM   22   C  CA   . PRO A 1 25  ? -6.91102  2.88400   -16.57094 1.000 35.61897  ? 5   PRO A CA   1 
ATOM   23   C  C    . PRO A 1 25  ? -6.07652  3.88574   -15.78326 1.000 35.92217  ? 5   PRO A C    1 
ATOM   24   O  O    . PRO A 1 25  ? -5.22436  4.58368   -16.33518 1.000 36.72948  ? 5   PRO A O    1 
ATOM   25   C  CB   . PRO A 1 25  ? -6.10858  1.62599   -16.91885 1.000 39.15316  ? 5   PRO A CB   1 
ATOM   26   C  CG   . PRO A 1 25  ? -5.63825  1.84142   -18.30229 1.000 35.42052  ? 5   PRO A CG   1 
ATOM   27   C  CD   . PRO A 1 25  ? -6.61903  2.72175   -18.99358 1.000 34.10685  ? 5   PRO A CD   1 
ATOM   28   H  HA   . PRO A 1 25  ? -7.70032  2.63106   -16.06704 1.000 42.76652  ? 5   PRO A HA   1 
ATOM   29   H  HB2  . PRO A 1 25  ? -5.36038  1.53266   -16.30862 1.000 47.00756  ? 5   PRO A HB2  1 
ATOM   30   H  HB3  . PRO A 1 25  ? -6.68045  0.84438   -16.86458 1.000 47.00756  ? 5   PRO A HB3  1 
ATOM   31   H  HG2  . PRO A 1 25  ? -4.76599  2.26511   -18.27896 1.000 42.52838  ? 5   PRO A HG2  1 
ATOM   32   H  HG3  . PRO A 1 25  ? -5.57930  0.98542   -18.75473 1.000 42.52838  ? 5   PRO A HG3  1 
ATOM   33   H  HD2  . PRO A 1 25  ? -6.16854  3.33942   -19.59062 1.000 40.95199  ? 5   PRO A HD2  1 
ATOM   34   H  HD3  . PRO A 1 25  ? -7.26740  2.19603   -19.48768 1.000 40.95199  ? 5   PRO A HD3  1 
ATOM   35   N  N    . ASP A 1 26  ? -6.34947  3.97375   -14.48562 1.000 33.53001  ? 6   ASP A N    1 
ATOM   36   C  CA   . ASP A 1 26  ? -5.66564  4.91527   -13.60352 1.000 32.05014  ? 6   ASP A CA   1 
ATOM   37   C  C    . ASP A 1 26  ? -4.47302  4.18897   -13.03211 1.000 34.62785  ? 6   ASP A C    1 
ATOM   38   O  O    . ASP A 1 26  ? -4.57049  3.50366   -12.01424 1.000 36.73266  ? 6   ASP A O    1 
ATOM   39   C  CB   . ASP A 1 26  ? -6.60752  5.41579   -12.51488 1.000 36.05102  ? 6   ASP A CB   1 
ATOM   40   C  CG   . ASP A 1 26  ? -5.93594  6.35406   -11.53827 1.000 46.30661  ? 6   ASP A CG   1 
ATOM   41   O  OD1  . ASP A 1 26  ? -4.92414  6.97796   -11.89224 1.000 40.44135  ? 6   ASP A OD1  1 
ATOM   42   O  OD2  . ASP A 1 26  ? -6.45459  6.48495   -10.40520 1.000 54.04426  ? 6   ASP A OD2  1 
ATOM   43   H  H    . ASP A 1 26  ? -6.93711  3.49050   -14.08468 1.000 40.25978  ? 6   ASP A H    1 
ATOM   44   H  HA   . ASP A 1 26  ? -5.35868  5.68604   -14.10609 1.000 38.48393  ? 6   ASP A HA   1 
ATOM   45   H  HB2  . ASP A 1 26  ? -7.34342  5.89262   -12.92958 1.000 43.28498  ? 6   ASP A HB2  1 
ATOM   46   H  HB3  . ASP A 1 26  ? -6.94429  4.65548   -12.01547 1.000 43.28498  ? 6   ASP A HB3  1 
ATOM   47   N  N    . VAL A 1 27  ? -3.33660  4.29012   -13.73169 1.000 28.54440  ? 7   VAL A N    1 
ATOM   48   C  CA   . VAL A 1 27  ? -2.18565  3.48808   -13.37506 1.000 28.75356  ? 7   VAL A CA   1 
ATOM   49   C  C    . VAL A 1 27  ? -0.93492  4.34402   -13.34970 1.000 27.34937  ? 7   VAL A C    1 
ATOM   50   O  O    . VAL A 1 27  ? -0.84617  5.38575   -14.00220 1.000 28.10091  ? 7   VAL A O    1 
ATOM   51   C  CB   . VAL A 1 27  ? -1.97301  2.30472   -14.33927 1.000 29.00508  ? 7   VAL A CB   1 
ATOM   52   C  CG1  . VAL A 1 27  ? -3.14358  1.32254   -14.23642 1.000 33.60508  ? 7   VAL A CG1  1 
ATOM   53   C  CG2  . VAL A 1 27  ? -1.80072  2.79594   -15.76986 1.000 29.86627  ? 7   VAL A CG2  1 
ATOM   54   H  H    . VAL A 1 27  ? -3.22041  4.81183   -14.40543 1.000 34.27704  ? 7   VAL A H    1 
ATOM   55   H  HA   . VAL A 1 27  ? -2.33228  3.14888   -12.47821 1.000 34.52804  ? 7   VAL A HA   1 
ATOM   56   H  HB   . VAL A 1 27  ? -1.16048  1.83739   -14.08970 1.000 34.82985  ? 7   VAL A HB   1 
ATOM   57   H  HG11 . VAL A 1 27  ? -2.96689  0.55961   -14.80880 1.000 40.34986  ? 7   VAL A HG11 1 
ATOM   58   H  HG12 . VAL A 1 27  ? -3.23172  1.03162   -13.31529 1.000 40.34986  ? 7   VAL A HG12 1 
ATOM   59   H  HG13 . VAL A 1 27  ? -3.95625  1.76881   -14.52157 1.000 40.34986  ? 7   VAL A HG13 1 
ATOM   60   H  HG21 . VAL A 1 27  ? -1.76251  2.03031   -16.36421 1.000 35.86328  ? 7   VAL A HG21 1 
ATOM   61   H  HG22 . VAL A 1 27  ? -2.55538  3.35876   -16.00355 1.000 35.86328  ? 7   VAL A HG22 1 
ATOM   62   H  HG23 . VAL A 1 27  ? -0.97704  3.30444   -15.83212 1.000 35.86328  ? 7   VAL A HG23 1 
ATOM   63   N  N    . ASP A 1 28  ? 0.03830   3.86865   -12.56724 1.000 26.77086  ? 8   ASP A N    1 
ATOM   64   C  CA   . ASP A 1 28  ? 1.38208   4.43616   -12.47291 1.000 27.82345  ? 8   ASP A CA   1 
ATOM   65   C  C    . ASP A 1 28  ? 2.35352   3.35912   -12.95802 1.000 26.17469  ? 8   ASP A C    1 
ATOM   66   O  O    . ASP A 1 28  ? 2.60663   2.36653   -12.26033 1.000 24.12803  ? 8   ASP A O    1 
ATOM   67   C  CB   . ASP A 1 28  ? 1.64692   4.89604   -11.03708 1.000 29.42025  ? 8   ASP A CB   1 
ATOM   68   C  CG   . ASP A 1 28  ? 3.03417   5.42528   -10.82222 1.000 29.05746  ? 8   ASP A CG   1 
ATOM   69   O  OD1  . ASP A 1 28  ? 3.90591   5.25073   -11.69716 1.000 27.78091  ? 8   ASP A OD1  1 
ATOM   70   O  OD2  . ASP A 1 28  ? 3.26998   6.00689   -9.73278  1.000 33.61959  ? 8   ASP A OD2  1 
ATOM   71   H  H    . ASP A 1 28  ? -0.06357  3.18373   -12.05724 1.000 32.14880  ? 8   ASP A H    1 
ATOM   72   H  HA   . ASP A 1 28  ? 1.49585   5.20876   -13.04828 1.000 33.41191  ? 8   ASP A HA   1 
ATOM   73   H  HB2  . ASP A 1 28  ? 1.02199   5.60386   -10.81496 1.000 35.32806  ? 8   ASP A HB2  1 
ATOM   74   H  HB3  . ASP A 1 28  ? 1.52119   4.14273   -10.43907 1.000 35.32806  ? 8   ASP A HB3  1 
ATOM   75   N  N    . LEU A 1 29  ? 2.89460   3.54077   -14.17362 1.000 22.79714  ? 9   LEU A N    1 
ATOM   76   C  CA   . LEU A 1 29  ? 3.76847   2.51832   -14.76948 1.000 23.38775  ? 9   LEU A CA   1 
ATOM   77   C  C    . LEU A 1 29  ? 5.15370   2.47938   -14.14724 1.000 22.91654  ? 9   LEU A C    1 
ATOM   78   O  O    . LEU A 1 29  ? 5.93298   1.60029   -14.49370 1.000 22.45584  ? 9   LEU A O    1 
ATOM   79   C  CB   . LEU A 1 29  ? 3.85149   2.74026   -16.28881 1.000 21.96620  ? 9   LEU A CB   1 
ATOM   80   C  CG   . LEU A 1 29  ? 2.53004   2.44549   -16.99404 1.000 26.05101  ? 9   LEU A CG   1 
ATOM   81   C  CD1  . LEU A 1 29  ? 2.70938   2.76822   -18.48211 1.000 26.91545  ? 9   LEU A CD1  1 
ATOM   82   C  CD2  . LEU A 1 29  ? 2.07264   0.98412   -16.81068 1.000 25.08975  ? 9   LEU A CD2  1 
ATOM   83   H  H    . LEU A 1 29  ? 2.77250   4.23621   -14.66460 1.000 27.38033  ? 9   LEU A H    1 
ATOM   84   H  HA   . LEU A 1 29  ? 3.37873   1.64203   -14.62414 1.000 28.08906  ? 9   LEU A HA   1 
ATOM   85   H  HB2  . LEU A 1 29  ? 4.08616   3.66558   -16.46088 1.000 26.38321  ? 9   LEU A HB2  1 
ATOM   86   H  HB3  . LEU A 1 29  ? 4.52885   2.15209   -16.65778 1.000 26.38321  ? 9   LEU A HB3  1 
ATOM   87   H  HG   . LEU A 1 29  ? 1.82920   2.99221   -16.60569 1.000 31.28497  ? 9   LEU A HG   1 
ATOM   88   H  HD11 . LEU A 1 29  ? 1.88023   2.57878   -18.94850 1.000 32.32231  ? 9   LEU A HD11 1 
ATOM   89   H  HD12 . LEU A 1 29  ? 2.93512   3.70683   -18.57672 1.000 32.32231  ? 9   LEU A HD12 1 
ATOM   90   H  HD13 . LEU A 1 29  ? 3.42362   2.21847   -18.84064 1.000 32.32231  ? 9   LEU A HD13 1 
ATOM   91   H  HD21 . LEU A 1 29  ? 1.39610   0.77926   -17.47493 1.000 30.13146  ? 9   LEU A HD21 1 
ATOM   92   H  HD22 . LEU A 1 29  ? 2.83661   0.39741   -16.92481 1.000 30.13146  ? 9   LEU A HD22 1 
ATOM   93   H  HD23 . LEU A 1 29  ? 1.70423   0.87796   -15.91967 1.000 30.13146  ? 9   LEU A HD23 1 
ATOM   94   N  N    . ALA A 1 30  ? 5.47273   3.37228   -13.22741 1.000 22.57393  ? 10  ALA A N    1 
ATOM   95   C  CA   . ALA A 1 30  ? 6.69026   3.29282   -12.43138 1.000 25.30553  ? 10  ALA A CA   1 
ATOM   96   C  C    . ALA A 1 30  ? 6.45064   2.68070   -11.05113 1.000 25.39853  ? 10  ALA A C    1 
ATOM   97   O  O    . ALA A 1 30  ? 7.38182   2.59642   -10.24213 1.000 25.41728  ? 10  ALA A O    1 
ATOM   98   C  CB   . ALA A 1 30  ? 7.30918   4.69079   -12.29295 1.000 29.02120  ? 10  ALA A CB   1 
ATOM   99   H  H    . ALA A 1 30  ? 4.98677   4.05597   -13.03763 1.000 27.11248  ? 10  ALA A H    1 
ATOM   100  H  HA   . ALA A 1 30  ? 7.33503   2.73065   -12.88871 1.000 30.39040  ? 10  ALA A HA   1 
ATOM   101  H  HB1  . ALA A 1 30  ? 8.11247   4.62845   -11.75283 1.000 34.84920  ? 10  ALA A HB1  1 
ATOM   102  H  HB2  . ALA A 1 30  ? 7.52936   5.02749   -13.17560 1.000 34.84920  ? 10  ALA A HB2  1 
ATOM   103  H  HB3  . ALA A 1 30  ? 6.66767   5.27920   -11.86500 1.000 34.84920  ? 10  ALA A HB3  1 
ATOM   104  N  N    . ASP A 1 31  ? 5.22401   2.26843   -10.75201 1.000 24.54633  ? 11  ASP A N    1 
ATOM   105  C  CA   . ASP A 1 31  ? 4.88230   1.68873   -9.46119  1.000 25.68934  ? 11  ASP A CA   1 
ATOM   106  C  C    . ASP A 1 31  ? 4.96827   0.16545   -9.54793  1.000 25.45584  ? 11  ASP A C    1 
ATOM   107  O  O    . ASP A 1 31  ? 4.26050   -0.47109  -10.34050 1.000 25.13082  ? 11  ASP A O    1 
ATOM   108  C  CB   . ASP A 1 31  ? 3.47950   2.15181   -9.08984  1.000 26.85378  ? 11  ASP A CB   1 
ATOM   109  C  CG   . ASP A 1 31  ? 3.00127   1.67582   -7.73237  1.000 33.15808  ? 11  ASP A CG   1 
ATOM   110  O  OD1  . ASP A 1 31  ? 3.61526   0.80091   -7.10512  1.000 29.94259  ? 11  ASP A OD1  1 
ATOM   111  O  OD2  . ASP A 1 31  ? 1.99798   2.25473   -7.28288  1.000 40.80352  ? 11  ASP A OD2  1 
ATOM   112  H  H    . ASP A 1 31  ? 4.55752   2.31544   -11.29348 1.000 29.47935  ? 11  ASP A H    1 
ATOM   113  H  HA   . ASP A 1 31  ? 5.50681   1.96679   -8.77302  1.000 30.85097  ? 11  ASP A HA   1 
ATOM   114  H  HB2  . ASP A 1 31  ? 3.46555   3.12168   -9.08170  1.000 32.24830  ? 11  ASP A HB2  1 
ATOM   115  H  HB3  . ASP A 1 31  ? 2.85682   1.81662   -9.75377  1.000 32.24830  ? 11  ASP A HB3  1 
ATOM   116  N  N    . GLY A 1 32  ? 5.83194   -0.42489  -8.72727  1.000 23.93637  ? 12  GLY A N    1 
ATOM   117  C  CA   . GLY A 1 32  ? 5.95910   -1.88533  -8.74667  1.000 23.27033  ? 12  GLY A CA   1 
ATOM   118  C  C    . GLY A 1 32  ? 4.66985   -2.62821  -8.44400  1.000 23.40216  ? 12  GLY A C    1 
ATOM   119  O  O    . GLY A 1 32  ? 4.50698   -3.76952  -8.89593  1.000 23.53398  ? 12  GLY A O    1 
ATOM   120  H  H    . GLY A 1 32  ? 6.34161   -0.01896  -8.16597  1.000 28.74740  ? 12  GLY A H    1 
ATOM   121  H  HA2  . GLY A 1 32  ? 6.26301   -2.16165  -9.62541  1.000 27.94816  ? 12  GLY A HA2  1 
ATOM   122  H  HA3  . GLY A 1 32  ? 6.61823   -2.15116  -8.08653  1.000 27.94816  ? 12  GLY A HA3  1 
ATOM   123  N  N    . ASN A 1 33  ? 3.73807   -1.99846  -7.72441  1.000 23.05805  ? 13  ASN A N    1 
ATOM   124  C  CA   . ASN A 1 33  ? 2.46218   -2.66262  -7.44752  1.000 25.98738  ? 13  ASN A CA   1 
ATOM   125  C  C    . ASN A 1 33  ? 1.62851   -2.88746  -8.71102  1.000 25.14479  ? 13  ASN A C    1 
ATOM   126  O  O    . ASN A 1 33  ? 0.82467   -3.84142  -8.76259  1.000 24.82270  ? 13  ASN A O    1 
ATOM   127  C  CB   . ASN A 1 33  ? 1.68277   -1.85723  -6.43002  1.000 26.87152  ? 13  ASN A CB   1 
ATOM   128  C  CG   . ASN A 1 33  ? 2.28419   -1.96513  -5.03180  1.000 30.47849  ? 13  ASN A CG   1 
ATOM   129  O  OD1  . ASN A 1 33  ? 2.76582   -3.02235  -4.64389  1.000 30.38135  ? 13  ASN A OD1  1 
ATOM   130  N  ND2  . ASN A 1 33  ? 2.28144   -0.87450  -4.30020  1.000 39.90533  ? 13  ASN A ND2  1 
ATOM   131  H  H    . ASN A 1 33  ? 3.81656   -1.20845  -7.39377  1.000 27.69343  ? 13  ASN A H    1 
ATOM   132  H  HA   . ASN A 1 33  ? 2.64548   -3.53818  -7.07242  1.000 31.20861  ? 13  ASN A HA   1 
ATOM   133  H  HB2  . ASN A 1 33  ? 1.68834   -0.92300  -6.69093  1.000 32.26959  ? 13  ASN A HB2  1 
ATOM   134  H  HB3  . ASN A 1 33  ? 0.77096   -2.18615  -6.39381  1.000 32.26959  ? 13  ASN A HB3  1 
ATOM   135  H  HD21 . ASN A 1 33  ? 2.61021   -0.88888  -3.50565  1.000 47.91016  ? 13  ASN A HD21 1 
ATOM   136  H  HD22 . ASN A 1 33  ? 1.95088   -0.14593  -4.61566  1.000 47.91016  ? 13  ASN A HD22 1 
ATOM   137  N  N    . PHE A 1 34  ? 1.79886   -2.04751  -9.74130  1.000 22.56062  ? 14  PHE A N    1 
ATOM   138  C  CA   . PHE A 1 34  ? 1.11563   -2.29851  -11.00643 1.000 21.86181  ? 14  PHE A CA   1 
ATOM   139  C  C    . PHE A 1 34  ? 1.49583   -3.65099  -11.59428 1.000 21.95181  ? 14  PHE A C    1 
ATOM   140  O  O    . PHE A 1 34  ? 0.63417   -4.38887  -12.08334 1.000 23.20831  ? 14  PHE A O    1 
ATOM   141  C  CB   . PHE A 1 34  ? 1.42678   -1.17140  -12.00417 1.000 22.05170  ? 14  PHE A CB   1 
ATOM   142  C  CG   . PHE A 1 34  ? 0.91774   -1.42952  -13.39469 1.000 21.60517  ? 14  PHE A CG   1 
ATOM   143  C  CD1  . PHE A 1 34  ? -0.39365  -1.16401  -13.73010 1.000 23.78878  ? 14  PHE A CD1  1 
ATOM   144  C  CD2  . PHE A 1 34  ? 1.73079   -1.98187  -14.35805 1.000 20.60106  ? 14  PHE A CD2  1 
ATOM   145  C  CE1  . PHE A 1 34  ? -0.87646  -1.41816  -14.98872 1.000 25.49913  ? 14  PHE A CE1  1 
ATOM   146  C  CE2  . PHE A 1 34  ? 1.26180   -2.25893  -15.64149 1.000 22.81111  ? 14  PHE A CE2  1 
ATOM   147  C  CZ   . PHE A 1 34  ? -0.04481  -1.96885  -15.97697 1.000 23.72916  ? 14  PHE A CZ   1 
ATOM   148  H  H    . PHE A 1 34  ? 2.29313   -1.34383  -9.72985  1.000 27.09650  ? 14  PHE A H    1 
ATOM   149  H  HA   . PHE A 1 34  ? 0.15951   -2.30616  -10.84312 1.000 26.25793  ? 14  PHE A HA   1 
ATOM   150  H  HB2  . PHE A 1 34  ? 1.01545   -0.35237  -11.68652 1.000 26.48580  ? 14  PHE A HB2  1 
ATOM   151  H  HB3  . PHE A 1 34  ? 2.38889   -1.06028  -12.05791 1.000 26.48580  ? 14  PHE A HB3  1 
ATOM   152  H  HD1  . PHE A 1 34  ? -0.96317  -0.80468  -13.08867 1.000 28.57030  ? 14  PHE A HD1  1 
ATOM   153  H  HD2  . PHE A 1 34  ? 2.61576   -2.17528  -14.14752 1.000 24.74504  ? 14  PHE A HD2  1 
ATOM   154  H  HE1  . PHE A 1 34  ? -1.76349  -1.22378  -15.18944 1.000 30.62272  ? 14  PHE A HE1  1 
ATOM   155  H  HE2  . PHE A 1 34  ? 1.82994   -2.63947  -16.27182 1.000 27.39709  ? 14  PHE A HE2  1 
ATOM   156  H  HZ   . PHE A 1 34  ? -0.36582  -2.13355  -16.83413 1.000 28.49876  ? 14  PHE A HZ   1 
ATOM   157  N  N    . TYR A 1 35  ? 2.78317   -4.00125  -11.56490 1.000 21.01394  ? 15  TYR A N    1 
ATOM   158  C  CA   . TYR A 1 35  ? 3.28562   -5.19818  -12.21981 1.000 21.85062  ? 15  TYR A CA   1 
ATOM   159  C  C    . TYR A 1 35  ? 3.04756   -6.44345  -11.39039 1.000 24.17700  ? 15  TYR A C    1 
ATOM   160  O  O    . TYR A 1 35  ? 3.10058   -7.54663  -11.94202 1.000 24.11611  ? 15  TYR A O    1 
ATOM   161  C  CB   . TYR A 1 35  ? 4.77767   -5.02857  -12.55281 1.000 21.17410  ? 15  TYR A CB   1 
ATOM   162  C  CG   . TYR A 1 35  ? 4.98418   -3.85042  -13.49060 1.000 20.46571  ? 15  TYR A CG   1 
ATOM   163  C  CD1  . TYR A 1 35  ? 4.83049   -3.98890  -14.85518 1.000 19.23562  ? 15  TYR A CD1  1 
ATOM   164  C  CD2  . TYR A 1 35  ? 5.29856   -2.59331  -12.99098 1.000 20.15210  ? 15  TYR A CD2  1 
ATOM   165  C  CE1  . TYR A 1 35  ? 5.01967   -2.88685  -15.71417 1.000 19.05082  ? 15  TYR A CE1  1 
ATOM   166  C  CE2  . TYR A 1 35  ? 5.44212   -1.52652  -13.80823 1.000 20.38315  ? 15  TYR A CE2  1 
ATOM   167  C  CZ   . TYR A 1 35  ? 5.31295   -1.68116  -15.16522 1.000 20.96358  ? 15  TYR A CZ   1 
ATOM   168  O  OH   . TYR A 1 35  ? 5.44320   -0.59568  -16.03030 1.000 22.96861  ? 15  TYR A OH   1 
ATOM   169  H  H    . TYR A 1 35  ? 3.39457   -3.54968  -11.16257 1.000 25.24049  ? 15  TYR A H    1 
ATOM   170  H  HA   . TYR A 1 35  ? 2.82908   -5.32603  -13.06606 1.000 26.24450  ? 15  TYR A HA   1 
ATOM   171  H  HB2  . TYR A 1 35  ? 5.27555   -4.86551  -11.73646 1.000 25.43269  ? 15  TYR A HB2  1 
ATOM   172  H  HB3  . TYR A 1 35  ? 5.10623   -5.83129  -12.98706 1.000 25.43269  ? 15  TYR A HB3  1 
ATOM   173  H  HD1  . TYR A 1 35  ? 4.60008   -4.81653  -15.21133 1.000 23.10651  ? 15  TYR A HD1  1 
ATOM   174  H  HD2  . TYR A 1 35  ? 5.41271   -2.48325  -12.07460 1.000 24.20629  ? 15  TYR A HD2  1 
ATOM   175  H  HE1  . TYR A 1 35  ? 4.94513   -2.98416  -16.63606 1.000 22.88475  ? 15  TYR A HE1  1 
ATOM   176  H  HE2  . TYR A 1 35  ? 5.62833   -0.68830  -13.45099 1.000 24.48355  ? 15  TYR A HE2  1 
ATOM   177  H  HH   . TYR A 1 35  ? 5.59287   0.10491   -15.59169 1.000 27.58610  ? 15  TYR A HH   1 
ATOM   178  N  N    . ALA A 1 36  ? 2.69294   -6.27851  -10.12444 1.000 23.03615  ? 16  ALA A N    1 
ATOM   179  C  CA   . ALA A 1 36  ? 2.35577   -7.41133  -9.28303  1.000 24.03478  ? 16  ALA A CA   1 
ATOM   180  C  C    . ALA A 1 36  ? 0.87316   -7.68499  -9.35963  1.000 28.73800  ? 16  ALA A C    1 
ATOM   181  O  O    . ALA A 1 36  ? 0.42275   -8.70584  -8.83566  1.000 27.33107  ? 16  ALA A O    1 
ATOM   182  C  CB   . ALA A 1 36  ? 2.80969   -7.16690  -7.83516  1.000 26.57359  ? 16  ALA A CB   1 
ATOM   183  H  H    . ALA A 1 36  ? 2.64037   -5.51636  -9.72953  1.000 27.66715  ? 16  ALA A H    1 
ATOM   184  H  HA   . ALA A 1 36  ? 2.83388   -8.20810  -9.56137  1.000 28.86549  ? 16  ALA A HA   1 
ATOM   185  H  HB1  . ALA A 1 36  ? 2.53691   -7.91950  -7.28736  1.000 31.91207  ? 16  ALA A HB1  1 
ATOM   186  H  HB2  . ALA A 1 36  ? 3.77545   -7.07792  -7.81773  1.000 31.91207  ? 16  ALA A HB2  1 
ATOM   187  H  HB3  . ALA A 1 36  ? 2.39653   -6.35260  -7.50787  1.000 31.91207  ? 16  ALA A HB3  1 
ATOM   188  N  N    . SER A 1 37  ? 0.12317   -6.81728  -10.05579 1.000 26.17925  ? 17  SER A N    1 
ATOM   189  C  CA   . SER A 1 37  ? -1.31260  -6.97793  -10.25246 1.000 32.16968  ? 17  SER A CA   1 
ATOM   190  C  C    . SER A 1 37  ? -1.58324  -7.86123  -11.47684 1.000 27.76350  ? 17  SER A C    1 
ATOM   191  O  O    . SER A 1 37  ? -1.03651  -7.63782  -12.57941 1.000 31.58845  ? 17  SER A O    1 
ATOM   192  C  CB   . SER A 1 37  ? -1.98391  -5.60096  -10.43284 1.000 28.83660  ? 17  SER A CB   1 
ATOM   193  O  OG   . SER A 1 37  ? -3.32386  -5.82175  -10.88815 1.000 37.48438  ? 17  SER A OG   1 
ATOM   194  H  H    . SER A 1 37  ? 0.43783   -6.11055  -10.43145 1.000 31.43886  ? 17  SER A H    1 
ATOM   195  H  HA   . SER A 1 37  ? -1.69709  -7.41329  -9.47558  1.000 38.62738  ? 17  SER A HA   1 
ATOM   196  H  HB2  . SER A 1 37  ? -1.99947  -5.13050  -9.58471  1.000 34.62769  ? 17  SER A HB2  1 
ATOM   197  H  HB3  . SER A 1 37  ? -1.49557  -5.08217  -11.09108 1.000 34.62769  ? 17  SER A HB3  1 
ATOM   198  H  HG   . SER A 1 37  ? -3.71507  -5.08645  -10.99719 1.000 45.00502  ? 17  SER A HG   1 
ATOM   199  N  N    . ARG A 1 38  ? -2.43720  -8.85138  -11.29653 1.000 33.24626  ? 18  ARG A N    1 
ATOM   200  C  CA   . ARG A 1 38  ? -2.92309  -9.64750  -12.39888 1.000 34.95649  ? 18  ARG A CA   1 
ATOM   201  C  C    . ARG A 1 38  ? -3.99769  -8.91847  -13.20462 1.000 32.60520  ? 18  ARG A C    1 
ATOM   202  O  O    . ARG A 1 38  ? -4.64311  -9.54288  -14.05710 1.000 38.42196  ? 18  ARG A O    1 
ATOM   203  C  CB   . ARG A 1 38  ? -3.43380  -10.97429 -11.85712 1.000 38.39660  ? 18  ARG A CB   1 
ATOM   204  C  CG   . ARG A 1 38  ? -2.28804  -11.71467 -11.13187 1.000 40.26581  ? 18  ARG A CG   1 
ATOM   205  C  CD   . ARG A 1 38  ? -2.64758  -13.12127 -10.74708 1.000 44.26899  ? 18  ARG A CD   1 
ATOM   206  N  NE   . ARG A 1 38  ? -1.48901  -13.80945 -10.18944 1.000 40.36671  ? 18  ARG A NE   1 
ATOM   207  C  CZ   . ARG A 1 38  ? -0.58528  -14.44943 -10.91106 1.000 44.35288  ? 18  ARG A CZ   1 
ATOM   208  N  NH1  . ARG A 1 38  ? -0.64964  -14.46822 -12.23244 1.000 54.74166  ? 18  ARG A NH1  1 
ATOM   209  N  NH2  . ARG A 1 38  ? 0.40307   -15.09159 -10.29101 1.000 35.52247  ? 18  ARG A NH2  1 
ATOM   210  H  H    . ARG A 1 38  ? -2.75365  -9.08339  -10.53126 1.000 39.91927  ? 18  ARG A H    1 
ATOM   211  H  HA   . ARG A 1 38  ? -2.20209  -9.84747  -13.01619 1.000 41.97155  ? 18  ARG A HA   1 
ATOM   212  H  HB2  . ARG A 1 38  ? -4.15317  -10.81537 -11.22613 1.000 46.09968  ? 18  ARG A HB2  1 
ATOM   213  H  HB3  . ARG A 1 38  ? -3.75034  -11.52684 -12.58883 1.000 46.09968  ? 18  ARG A HB3  1 
ATOM   214  H  HG2  . ARG A 1 38  ? -1.51667  -11.75387 -11.71868 1.000 48.34273  ? 18  ARG A HG2  1 
ATOM   215  H  HG3  . ARG A 1 38  ? -2.06389  -11.23167 -10.32108 1.000 48.34273  ? 18  ARG A HG3  1 
ATOM   216  H  HD2  . ARG A 1 38  ? -3.34983  -13.10582 -10.07813 1.000 53.14655  ? 18  ARG A HD2  1 
ATOM   217  H  HD3  . ARG A 1 38  ? -2.94746  -13.60632 -11.53175 1.000 53.14655  ? 18  ARG A HD3  1 
ATOM   218  H  HE   . ARG A 1 38  ? -1.38720  -13.79814 -9.33556  1.000 48.46381  ? 18  ARG A HE   1 
ATOM   219  H  HH11 . ARG A 1 38  ? -1.28825  -14.05890 -12.63770 1.000 65.71375  ? 18  ARG A HH11 1 
ATOM   220  H  HH12 . ARG A 1 38  ? -0.05287  -14.88975 -12.68606 1.000 65.71375  ? 18  ARG A HH12 1 
ATOM   221  H  HH21 . ARG A 1 38  ? 0.44719   -15.08620 -9.43216  1.000 42.65072  ? 18  ARG A HH21 1 
ATOM   222  H  HH22 . ARG A 1 38  ? 0.99717   -15.51166 -10.74947 1.000 42.65072  ? 18  ARG A HH22 1 
ATOM   223  N  N    . GLU A 1 39  ? -4.16312  -7.63387  -12.95319 1.000 32.95449  ? 19  GLU A N    1 
ATOM   224  C  CA   . GLU A 1 39  ? -4.94137  -6.75718  -13.81380 1.000 38.32064  ? 19  GLU A CA   1 
ATOM   225  C  C    . GLU A 1 39  ? -4.08834  -5.85087  -14.70920 1.000 30.83388  ? 19  GLU A C    1 
ATOM   226  O  O    . GLU A 1 39  ? -4.65010  -5.04797  -15.46522 1.000 29.63970  ? 19  GLU A O    1 
ATOM   227  C  CB   . GLU A 1 39  ? -5.90234  -5.93001  -12.95228 1.000 40.39777  ? 19  GLU A CB   1 
ATOM   228  C  CG   . GLU A 1 39  ? -6.71338  -6.81020  -11.96609 1.000 57.46623  ? 19  GLU A CG   1 
ATOM   229  C  CD   . GLU A 1 39  ? -7.98231  -6.14984  -11.43690 1.000 66.59127  ? 19  GLU A CD   1 
ATOM   230  O  OE1  . GLU A 1 39  ? -8.09290  -5.94499  -10.20907 1.000 69.32900  ? 19  GLU A OE1  1 
ATOM   231  O  OE2  . GLU A 1 39  ? -8.88093  -5.84861  -12.24552 1.000 72.78504  ? 19  GLU A OE2  1 
ATOM   232  H  H    . GLU A 1 39  ? -3.82589  -7.23267  -12.27134 1.000 39.56915  ? 19  GLU A H    1 
ATOM   233  H  HA   . GLU A 1 39  ? -5.47324  -7.29848  -14.41797 1.000 46.00852  ? 19  GLU A HA   1 
ATOM   234  H  HB2  . GLU A 1 39  ? -5.39199  -5.28760  -12.43483 1.000 48.50109  ? 19  GLU A HB2  1 
ATOM   235  H  HB3  . GLU A 1 39  ? -6.52899  -5.46744  -13.53041 1.000 48.50109  ? 19  GLU A HB3  1 
ATOM   236  H  HG2  . GLU A 1 39  ? -6.97460  -7.62618  -12.42089 1.000 68.98324  ? 19  GLU A HG2  1 
ATOM   237  H  HG3  . GLU A 1 39  ? -6.15179  -7.02054  -11.20367 1.000 68.98324  ? 19  GLU A HG3  1 
ATOM   238  N  N    . ALA A 1 40  ? -2.75982  -6.00264  -14.70839 1.000 27.77355  ? 20  ALA A N    1 
ATOM   239  C  CA   . ALA A 1 40  ? -1.92471  -5.24980  -15.63781 1.000 26.75071  ? 20  ALA A CA   1 
ATOM   240  C  C    . ALA A 1 40  ? -2.31190  -5.55904  -17.08841 1.000 24.17581  ? 20  ALA A C    1 
ATOM   241  O  O    . ALA A 1 40  ? -2.35680  -4.66312  -17.95231 1.000 23.95522  ? 20  ALA A O    1 
ATOM   242  C  CB   . ALA A 1 40  ? -0.44312  -5.57598  -15.39570 1.000 28.27868  ? 20  ALA A CB   1 
ATOM   243  H  H    . ALA A 1 40  ? -2.32551  -6.52922  -14.18523 1.000 33.35203  ? 20  ALA A H    1 
ATOM   244  H  HA   . ALA A 1 40  ? -2.05175  -4.30080  -15.48238 1.000 32.12461  ? 20  ALA A HA   1 
ATOM   245  H  HB1  . ALA A 1 40  ? 0.09742   -5.07791  -16.02867 1.000 33.95818  ? 20  ALA A HB1  1 
ATOM   246  H  HB2  . ALA A 1 40  ? -0.20814  -5.32316  -14.48919 1.000 33.95818  ? 20  ALA A HB2  1 
ATOM   247  H  HB3  . ALA A 1 40  ? -0.30496  -6.52801  -15.51994 1.000 33.95818  ? 20  ALA A HB3  1 
ATOM   248  N  N    . ARG A 1 41  ? -2.53394  -6.83250  -17.40234 1.000 23.94878  ? 21  ARG A N    1 
ATOM   249  C  CA   . ARG A 1 41  ? -2.78330  -7.14203  -18.80541 1.000 22.63543  ? 21  ARG A CA   1 
ATOM   250  C  C    . ARG A 1 41  ? -4.09786  -6.52794  -19.27511 1.000 22.77332  ? 21  ARG A C    1 
ATOM   251  O  O    . ARG A 1 41  ? -4.19394  -6.14812  -20.44629 1.000 21.67532  ? 21  ARG A O    1 
ATOM   252  C  CB   . ARG A 1 41  ? -2.72851  -8.64665  -19.06056 1.000 22.65587  ? 21  ARG A CB   1 
ATOM   253  C  CG   . ARG A 1 41  ? -1.25115  -9.14563  -18.98919 1.000 24.11645  ? 21  ARG A CG   1 
ATOM   254  C  CD   . ARG A 1 41  ? -0.92938  -10.23128 -19.98517 1.000 27.55799  ? 21  ARG A CD   1 
ATOM   255  N  NE   . ARG A 1 41  ? -1.53091  -11.50659 -19.60181 1.000 27.48291  ? 21  ARG A NE   1 
ATOM   256  C  CZ   . ARG A 1 41  ? -0.91873  -12.43031 -18.87351 1.000 31.74310  ? 21  ARG A CZ   1 
ATOM   257  N  NH1  . ARG A 1 41  ? 0.27026   -12.22203 -18.34647 1.000 29.81051  ? 21  ARG A NH1  1 
ATOM   258  N  NH2  . ARG A 1 41  ? -1.49295  -13.61024 -18.70803 1.000 29.29797  ? 21  ARG A NH2  1 
ATOM   259  H  H    . ARG A 1 41  ? -2.54498  -7.49598  -16.85528 1.000 28.76229  ? 21  ARG A H    1 
ATOM   260  H  HA   . ARG A 1 41  ? -2.07208  -6.76102  -19.34384 1.000 27.18628  ? 21  ARG A HA   1 
ATOM   261  H  HB2  . ARG A 1 41  ? -3.24784  -9.11125  -18.38576 1.000 27.21081  ? 21  ARG A HB2  1 
ATOM   262  H  HB3  . ARG A 1 41  ? -3.08138  -8.84113  -19.94292 1.000 27.21081  ? 21  ARG A HB3  1 
ATOM   263  H  HG2  . ARG A 1 41  ? -0.65937  -8.39764  -19.16589 1.000 28.96350  ? 21  ARG A HG2  1 
ATOM   264  H  HG3  . ARG A 1 41  ? -1.08288  -9.49935  -18.10180 1.000 28.96350  ? 21  ARG A HG3  1 
ATOM   265  H  HD2  . ARG A 1 41  ? -1.27523  -9.98061  -20.85606 1.000 33.09335  ? 21  ARG A HD2  1 
ATOM   266  H  HD3  . ARG A 1 41  ? 0.03227   -10.34948 -20.03156 1.000 33.09335  ? 21  ARG A HD3  1 
ATOM   267  H  HE   . ARG A 1 41  ? -2.33335  -11.66846 -19.86541 1.000 33.00325  ? 21  ARG A HE   1 
ATOM   268  H  HH11 . ARG A 1 41  ? 0.67024   -11.47096 -18.47100 1.000 35.79638  ? 21  ARG A HH11 1 
ATOM   269  H  HH12 . ARG A 1 41  ? 0.64661   -12.83711 -17.87781 1.000 35.79638  ? 21  ARG A HH12 1 
ATOM   270  H  HH21 . ARG A 1 41  ? -2.25561  -13.77201 -19.07105 1.000 35.18132  ? 21  ARG A HH21 1 
ATOM   271  H  HH22 . ARG A 1 41  ? -1.10366  -14.21569 -18.23741 1.000 35.18132  ? 21  ARG A HH22 1 
ATOM   272  N  N    . ALA A 1 42  ? -5.09730  -6.37167  -18.39280 1.000 23.01763  ? 22  ALA A N    1 
ATOM   273  C  CA   . ALA A 1 42  ? -6.31359  -5.65099  -18.77936 1.000 25.64606  ? 22  ALA A CA   1 
ATOM   274  C  C    . ALA A 1 42  ? -6.02006  -4.18853  -19.11849 1.000 24.82314  ? 22  ALA A C    1 
ATOM   275  O  O    . ALA A 1 42  ? -6.62504  -3.60683  -20.04668 1.000 26.45555  ? 22  ALA A O    1 
ATOM   276  C  CB   . ALA A 1 42  ? -7.35861  -5.74615  -17.66863 1.000 28.33927  ? 22  ALA A CB   1 
ATOM   277  H  H    . ALA A 1 42  ? -5.09403  -6.66670  -17.58500 1.000 27.64492  ? 22  ALA A H    1 
ATOM   278  H  HA   . ALA A 1 42  ? -6.67924  -6.07098  -19.57360 1.000 30.79904  ? 22  ALA A HA   1 
ATOM   279  H  HB1  . ALA A 1 42  ? -8.15739  -5.27022  -17.94494 1.000 34.03088  ? 22  ALA A HB1  1 
ATOM   280  H  HB2  . ALA A 1 42  ? -7.56790  -6.68012  -17.51112 1.000 34.03088  ? 22  ALA A HB2  1 
ATOM   281  H  HB3  . ALA A 1 42  ? -6.99849  -5.34713  -16.86118 1.000 34.03088  ? 22  ALA A HB3  1 
ATOM   282  N  N    . ALA A 1 43  ? -5.12634  -3.57021  -18.34670 1.000 22.49253  ? 23  ALA A N    1 
ATOM   283  C  CA   . ALA A 1 43  ? -4.73036  -2.19219  -18.60320 1.000 24.70693  ? 23  ALA A CA   1 
ATOM   284  C  C    . ALA A 1 43  ? -3.98454  -2.09148  -19.92493 1.000 22.78887  ? 23  ALA A C    1 
ATOM   285  O  O    . ALA A 1 43  ? -4.26867  -1.20581  -20.73024 1.000 22.22267  ? 23  ALA A O    1 
ATOM   286  C  CB   . ALA A 1 43  ? -3.84715  -1.65786  -17.47717 1.000 24.31337  ? 23  ALA A CB   1 
ATOM   287  H  H    . ALA A 1 43  ? -4.73565  -3.92762  -17.66904 1.000 27.01480  ? 23  ALA A H    1 
ATOM   288  H  HA   . ALA A 1 43  ? -5.53112  -1.64585  -18.63775 1.000 29.67208  ? 23  ALA A HA   1 
ATOM   289  H  HB1  . ALA A 1 43  ? -3.58074  -0.74948  -17.68876 1.000 29.19981  ? 23  ALA A HB1  1 
ATOM   290  H  HB2  . ALA A 1 43  ? -4.35046  -1.67034  -16.64806 1.000 29.19981  ? 23  ALA A HB2  1 
ATOM   291  H  HB3  . ALA A 1 43  ? -3.06249  -2.22237  -17.39633 1.000 29.19981  ? 23  ALA A HB3  1 
ATOM   292  N  N    . TYR A 1 44  ? -3.06345  -3.01797  -20.18953 1.000 21.69637  ? 24  TYR A N    1 
ATOM   293  C  CA   . TYR A 1 44  ? -2.34790  -3.00300  -21.46125 1.000 21.55580  ? 24  TYR A CA   1 
ATOM   294  C  C    . TYR A 1 44  ? -3.30251  -3.14796  -22.63528 1.000 23.14212  ? 24  TYR A C    1 
ATOM   295  O  O    . TYR A 1 44  ? -3.10516  -2.52143  -23.68883 1.000 21.69932  ? 24  TYR A O    1 
ATOM   296  C  CB   . TYR A 1 44  ? -1.37530  -4.16219  -21.53188 1.000 20.92306  ? 24  TYR A CB   1 
ATOM   297  C  CG   . TYR A 1 44  ? -0.21903  -4.20633  -20.58315 1.000 19.58172  ? 24  TYR A CG   1 
ATOM   298  C  CD1  . TYR A 1 44  ? 0.39824   -3.06420  -20.11822 1.000 19.92220  ? 24  TYR A CD1  1 
ATOM   299  C  CD2  . TYR A 1 44  ? 0.27284   -5.44152  -20.18911 1.000 19.90309  ? 24  TYR A CD2  1 
ATOM   300  C  CE1  . TYR A 1 44  ? 1.50572   -3.15921  -19.23782 1.000 20.45780  ? 24  TYR A CE1  1 
ATOM   301  C  CE2  . TYR A 1 44  ? 1.37513   -5.53708  -19.35470 1.000 19.66682  ? 24  TYR A CE2  1 
ATOM   302  C  CZ   . TYR A 1 44  ? 1.95526   -4.42000  -18.85976 1.000 20.57688  ? 24  TYR A CZ   1 
ATOM   303  O  OH   . TYR A 1 44  ? 3.06095   -4.51304  -18.03603 1.000 20.92385  ? 24  TYR A OH   1 
ATOM   304  H  H    . TYR A 1 44  ? -2.83816  -3.65544  -19.65805 1.000 26.05941  ? 24  TYR A H    1 
ATOM   305  H  HA   . TYR A 1 44  ? -1.87105  -2.16005  -21.51563 1.000 25.89073  ? 24  TYR A HA   1 
ATOM   306  H  HB2  . TYR A 1 44  ? -1.88188  -4.97560  -21.38145 1.000 25.13143  ? 24  TYR A HB2  1 
ATOM   307  H  HB3  . TYR A 1 44  ? -0.99535  -4.16823  -22.42435 1.000 25.13143  ? 24  TYR A HB3  1 
ATOM   308  H  HD1  . TYR A 1 44  ? 0.08710   -2.22874  -20.38301 1.000 23.93040  ? 24  TYR A HD1  1 
ATOM   309  H  HD2  . TYR A 1 44  ? -0.14316  -6.21725  -20.48925 1.000 23.90747  ? 24  TYR A HD2  1 
ATOM   310  H  HE1  . TYR A 1 44  ? 1.92402   -2.39226  -18.91890 1.000 24.57313  ? 24  TYR A HE1  1 
ATOM   311  H  HE2  . TYR A 1 44  ? 1.71754   -6.37312  -19.13404 1.000 23.62395  ? 24  TYR A HE2  1 
ATOM   312  H  HH   . TYR A 1 44  ? 3.32185   -5.31041  -17.99431 1.000 25.13239  ? 24  TYR A HH   1 
ATOM   313  N  N    . ARG A 1 45  ? -4.32486  -3.99811  -22.48814 1.000 20.82870  ? 25  ARG A N    1 
ATOM   314  C  CA   . ARG A 1 45  ? -5.31531  -4.17127  -23.54114 1.000 23.38648  ? 25  ARG A CA   1 
ATOM   315  C  C    . ARG A 1 45  ? -5.96685  -2.83271  -23.90836 1.000 22.33333  ? 25  ARG A C    1 
ATOM   316  O  O    . ARG A 1 45  ? -6.15965  -2.51647  -25.09482 1.000 23.62959  ? 25  ARG A O    1 
ATOM   317  C  CB   . ARG A 1 45  ? -6.39724  -5.16492  -23.08265 1.000 29.92154  ? 25  ARG A CB   1 
ATOM   318  C  CG   . ARG A 1 45  ? -6.10028  -6.62083  -23.37978 1.000 37.94499  ? 25  ARG A CG   1 
ATOM   319  C  CD   . ARG A 1 45  ? -7.39575  -7.45056  -23.50945 1.000 44.79305  ? 25  ARG A CD   1 
ATOM   320  N  NE   . ARG A 1 45  ? -8.17874  -7.45907  -22.27608 1.000 48.88221  ? 25  ARG A NE   1 
ATOM   321  C  CZ   . ARG A 1 45  ? -7.84095  -8.09430  -21.15578 1.000 50.39504  ? 25  ARG A CZ   1 
ATOM   322  N  NH1  . ARG A 1 45  ? -6.75654  -8.85014  -21.07647 1.000 39.56560  ? 25  ARG A NH1  1 
ATOM   323  N  NH2  . ARG A 1 45  ? -8.62332  -7.98496  -20.08893 1.000 56.60644  ? 25  ARG A NH2  1 
ATOM   324  H  H    . ARG A 1 45  ? -4.46278  -4.48160  -21.79042 1.000 25.01820  ? 25  ARG A H    1 
ATOM   325  H  HA   . ARG A 1 45  ? -4.87273  -4.52911  -24.32662 1.000 28.08754  ? 25  ARG A HA   1 
ATOM   326  H  HB2  . ARG A 1 45  ? -6.50390  -5.08043  -22.12224 1.000 35.92961  ? 25  ARG A HB2  1 
ATOM   327  H  HB3  . ARG A 1 45  ? -7.22843  -4.94097  -23.52973 1.000 35.92961  ? 25  ARG A HB3  1 
ATOM   328  H  HG2  . ARG A 1 45  ? -5.61294  -6.68471  -24.21603 1.000 45.55775  ? 25  ARG A HG2  1 
ATOM   329  H  HG3  . ARG A 1 45  ? -5.57075  -6.99410  -22.65786 1.000 45.55775  ? 25  ARG A HG3  1 
ATOM   330  H  HD2  . ARG A 1 45  ? -7.94611  -7.07201  -24.21281 1.000 53.77542  ? 25  ARG A HD2  1 
ATOM   331  H  HD3  . ARG A 1 45  ? -7.16509  -8.36753  -23.72593 1.000 53.77542  ? 25  ARG A HD3  1 
ATOM   332  H  HE   . ARG A 1 45  ? -8.91722  -7.01834  -22.27346 1.000 58.68241  ? 25  ARG A HE   1 
ATOM   333  H  HH11 . ARG A 1 45  ? -6.24564  -8.94243  -21.76208 1.000 47.50249  ? 25  ARG A HH11 1 
ATOM   334  H  HH12 . ARG A 1 45  ? -6.56318  -9.24872  -20.33935 1.000 47.50249  ? 25  ARG A HH12 1 
ATOM   335  H  HH21 . ARG A 1 45  ? -9.33816  -7.50836  -20.12695 1.000 67.95149  ? 25  ARG A HH21 1 
ATOM   336  H  HH22 . ARG A 1 45  ? -8.41533  -8.39073  -19.35976 1.000 67.95149  ? 25  ARG A HH22 1 
ATOM   337  N  N    . TRP A 1 46  ? -6.36430  -2.06094  -22.88974 1.000 24.32507  ? 26  TRP A N    1 
ATOM   338  C  CA   . TRP A 1 46  ? -6.96574  -0.74510  -23.12515 1.000 22.66642  ? 26  TRP A CA   1 
ATOM   339  C  C    . TRP A 1 46  ? -5.99783  0.15797   -23.89359 1.000 22.08506  ? 26  TRP A C    1 
ATOM   340  O  O    . TRP A 1 46  ? -6.38222  0.81499   -24.87875 1.000 23.20646  ? 26  TRP A O    1 
ATOM   341  C  CB   . TRP A 1 46  ? -7.39864  -0.09449  -21.80050 1.000 24.79593  ? 26  TRP A CB   1 
ATOM   342  C  CG   . TRP A 1 46  ? -8.24302  1.11553   -22.02608 1.000 24.62327  ? 26  TRP A CG   1 
ATOM   343  C  CD1  . TRP A 1 46  ? -9.60899  1.15612   -22.07428 1.000 27.92228  ? 26  TRP A CD1  1 
ATOM   344  C  CD2  . TRP A 1 46  ? -7.79537  2.45466   -22.30666 1.000 27.42215  ? 26  TRP A CD2  1 
ATOM   345  N  NE1  . TRP A 1 46  ? -10.03967 2.43420   -22.36605 1.000 31.03703  ? 26  TRP A NE1  1 
ATOM   346  C  CE2  . TRP A 1 46  ? -8.94003  3.24864   -22.49875 1.000 28.36525  ? 26  TRP A CE2  1 
ATOM   347  C  CE3  . TRP A 1 46  ? -6.54075  3.05678   -22.40417 1.000 27.07083  ? 26  TRP A CE3  1 
ATOM   348  C  CZ2  . TRP A 1 46  ? -8.86281  4.61220   -22.78439 1.000 33.54129  ? 26  TRP A CZ2  1 
ATOM   349  C  CZ3  . TRP A 1 46  ? -6.46911  4.40515   -22.67651 1.000 28.02979  ? 26  TRP A CZ3  1 
ATOM   350  C  CH2  . TRP A 1 46  ? -7.61923  5.17260   -22.86426 1.000 28.86296  ? 26  TRP A CH2  1 
ATOM   351  H  H    . TRP A 1 46  ? -6.29730  -2.27448  -22.05938 1.000 29.21385  ? 26  TRP A H    1 
ATOM   352  H  HA   . TRP A 1 46  ? -7.76767  -0.85997  -23.65865 1.000 27.22346  ? 26  TRP A HA   1 
ATOM   353  H  HB2  . TRP A 1 46  ? -7.91466  -0.73353  -21.28450 1.000 29.77888  ? 26  TRP A HB2  1 
ATOM   354  H  HB3  . TRP A 1 46  ? -6.60986  0.17342   -21.30355 1.000 29.77888  ? 26  TRP A HB3  1 
ATOM   355  H  HD1  . TRP A 1 46  ? -10.16781 0.42668   -21.93092 1.000 33.53049  ? 26  TRP A HD1  1 
ATOM   356  H  HE1  . TRP A 1 46  ? -10.85935 2.68027   -22.45077 1.000 37.26820  ? 26  TRP A HE1  1 
ATOM   357  H  HE3  . TRP A 1 46  ? -5.76572  2.55622   -22.28725 1.000 32.50876  ? 26  TRP A HE3  1 
ATOM   358  H  HZ2  . TRP A 1 46  ? -9.63001  5.12118   -22.91567 1.000 40.27331  ? 26  TRP A HZ2  1 
ATOM   359  H  HZ3  . TRP A 1 46  ? -5.63554  4.81313   -22.73660 1.000 33.65951  ? 26  TRP A HZ3  1 
ATOM   360  H  HH2  . TRP A 1 46  ? -7.53798  6.08088   -23.04683 1.000 34.65932  ? 26  TRP A HH2  1 
ATOM   361  N  N    . MET A 1 47  ? -4.72238  0.18968   -23.45668 1.000 21.53936  ? 27  MET A N    1 
ATOM   362  C  CA   . MET A 1 47  ? -3.71038  1.02096   -24.11824 1.000 21.41348  ? 27  MET A CA   1 
ATOM   363  C  C    . MET A 1 47  ? -3.60487  0.66308   -25.59231 1.000 22.32599  ? 27  MET A C    1 
ATOM   364  O  O    . MET A 1 47  ? -3.67532  1.53983   -26.47171 1.000 21.98559  ? 27  MET A O    1 
ATOM   365  C  CB   . MET A 1 47  ? -2.34636  0.84566   -23.43293 1.000 21.75371  ? 27  MET A CB   1 
ATOM   366  C  CG   . MET A 1 47  ? -2.32838  1.12993   -21.94025 1.000 22.96011  ? 27  MET A CG   1 
ATOM   367  S  SD   . MET A 1 47  ? -0.66262  0.73428   -21.33524 1.000 22.68330  ? 27  MET A SD   1 
ATOM   368  C  CE   . MET A 1 47  ? -0.98838  0.72938   -19.59730 1.000 24.58378  ? 27  MET A CE   1 
ATOM   369  H  H    . MET A 1 47  ? -4.42499  -0.25818  -22.78543 1.000 25.87100  ? 27  MET A H    1 
ATOM   370  H  HA   . MET A 1 47  ? -3.97059  1.95110   -24.02861 1.000 25.71994  ? 27  MET A HA   1 
ATOM   371  H  HB2  . MET A 1 47  ? -2.05779  -0.07215  -23.55640 1.000 26.12822  ? 27  MET A HB2  1 
ATOM   372  H  HB3  . MET A 1 47  ? -1.71416  1.45124   -23.85066 1.000 26.12822  ? 27  MET A HB3  1 
ATOM   373  H  HG2  . MET A 1 47  ? -2.51829  2.06643   -21.77347 1.000 27.57590  ? 27  MET A HG2  1 
ATOM   374  H  HG3  . MET A 1 47  ? -2.97827  0.57318   -21.48355 1.000 27.57590  ? 27  MET A HG3  1 
ATOM   375  H  HE1  . MET A 1 47  ? -0.16388  0.54184   -19.12199 1.000 29.52430  ? 27  MET A HE1  1 
ATOM   376  H  HE2  . MET A 1 47  ? -1.32941  1.59949   -19.33747 1.000 29.52430  ? 27  MET A HE2  1 
ATOM   377  H  HE3  . MET A 1 47  ? -1.64640  0.04419   -19.40127 1.000 29.52430  ? 27  MET A HE3  1 
ATOM   378  N  N    . ARG A 1 48  ? -3.49996  -0.63275  -25.88810 1.000 21.09231  ? 28  ARG A N    1 
ATOM   379  C  CA   . ARG A 1 48  ? -3.26824  -1.03905  -27.26514 1.000 21.61579  ? 28  ARG A CA   1 
ATOM   380  C  C    . ARG A 1 48  ? -4.46223  -0.68815  -28.14130 1.000 24.00070  ? 28  ARG A C    1 
ATOM   381  O  O    . ARG A 1 48  ? -4.28978  -0.38641  -29.32229 1.000 25.48877  ? 28  ARG A O    1 
ATOM   382  C  CB   . ARG A 1 48  ? -2.99553  -2.53991  -27.36658 1.000 22.01843  ? 28  ARG A CB   1 
ATOM   383  C  CG   . ARG A 1 48  ? -1.70091  -2.97581  -26.64722 1.000 20.86129  ? 28  ARG A CG   1 
ATOM   384  C  CD   . ARG A 1 48  ? -1.21910  -4.37369  -27.04577 1.000 22.88737  ? 28  ARG A CD   1 
ATOM   385  N  NE   . ARG A 1 48  ? -2.27466  -5.35998  -26.82730 1.000 24.13965  ? 28  ARG A NE   1 
ATOM   386  C  CZ   . ARG A 1 48  ? -2.45955  -5.99762  -25.67298 1.000 23.35345  ? 28  ARG A CZ   1 
ATOM   387  N  NH1  . ARG A 1 48  ? -1.59851  -5.89457  -24.66834 1.000 22.08419  ? 28  ARG A NH1  1 
ATOM   388  N  NH2  . ARG A 1 48  ? -3.55152  -6.74552  -25.51845 1.000 24.05874  ? 28  ARG A NH2  1 
ATOM   389  H  H    . ARG A 1 48  ? -3.55816  -1.27764  -25.32212 1.000 25.33453  ? 28  ARG A H    1 
ATOM   390  H  HA   . ARG A 1 48  ? -2.47846  -0.57539  -27.58478 1.000 25.96271  ? 28  ARG A HA   1 
ATOM   391  H  HB2  . ARG A 1 48  ? -3.73599  -3.02092  -26.96502 1.000 26.44588  ? 28  ARG A HB2  1 
ATOM   392  H  HB3  . ARG A 1 48  ? -2.91199  -2.78080  -28.30247 1.000 26.44588  ? 28  ARG A HB3  1 
ATOM   393  H  HG2  . ARG A 1 48  ? -0.99515  -2.34661  -26.86378 1.000 25.05731  ? 28  ARG A HG2  1 
ATOM   394  H  HG3  . ARG A 1 48  ? -1.86017  -2.97930  -25.69039 1.000 25.05731  ? 28  ARG A HG3  1 
ATOM   395  H  HD2  . ARG A 1 48  ? -0.98027  -4.37932  -27.98589 1.000 27.48861  ? 28  ARG A HD2  1 
ATOM   396  H  HD3  . ARG A 1 48  ? -0.45068  -4.61848  -26.50679 1.000 27.48861  ? 28  ARG A HD3  1 
ATOM   397  H  HE   . ARG A 1 48  ? -2.80559  -5.53847  -27.47987 1.000 28.99134  ? 28  ARG A HE   1 
ATOM   398  H  HH11 . ARG A 1 48  ? -0.89651  -5.40490  -24.75219 1.000 26.52478  ? 28  ARG A HH11 1 
ATOM   399  H  HH12 . ARG A 1 48  ? -1.74255  -6.31745  -23.93348 1.000 26.52478  ? 28  ARG A HH12 1 
ATOM   400  H  HH21 . ARG A 1 48  ? -4.12251  -6.81018  -26.15828 1.000 28.89425  ? 28  ARG A HH21 1 
ATOM   401  H  HH22 . ARG A 1 48  ? -3.68527  -7.16355  -24.77887 1.000 28.89425  ? 28  ARG A HH22 1 
ATOM   402  N  N    . ALA A 1 49  ? -5.68416  -0.71612  -27.58487 1.000 22.24680  ? 29  ALA A N    1 
ATOM   403  C  CA   . ALA A 1 49  ? -6.87696  -0.44194  -28.37102 1.000 23.47264  ? 29  ALA A CA   1 
ATOM   404  C  C    . ALA A 1 49  ? -7.21029  1.03952   -28.47954 1.000 26.68663  ? 29  ALA A C    1 
ATOM   405  O  O    . ALA A 1 49  ? -7.92944  1.41611   -29.41935 1.000 29.93808  ? 29  ALA A O    1 
ATOM   406  C  CB   . ALA A 1 49  ? -8.09051  -1.16804  -27.77234 1.000 25.45542  ? 29  ALA A CB   1 
ATOM   407  H  H    . ALA A 1 49  ? -5.83855  -0.89141  -26.75720 1.000 26.71993  ? 29  ALA A H    1 
ATOM   408  H  HA   . ALA A 1 49  ? -6.72481  -0.78127  -29.26690 1.000 28.19093  ? 29  ALA A HA   1 
ATOM   409  H  HB1  . ALA A 1 49  ? -8.88051  -0.93983  -28.28685 1.000 30.57026  ? 29  ALA A HB1  1 
ATOM   410  H  HB2  . ALA A 1 49  ? -7.93621  -2.12495  -27.81008 1.000 30.57026  ? 29  ALA A HB2  1 
ATOM   411  H  HB3  . ALA A 1 49  ? -8.20347  -0.88730  -26.85076 1.000 30.57026  ? 29  ALA A HB3  1 
ATOM   412  N  N    . ASN A 1 50  ? -6.71108  1.88409   -27.56450 1.000 23.89679  ? 30  ASN A N    1 
ATOM   413  C  CA   . ASN A 1 50  ? -7.17557  3.26319   -27.46168 1.000 23.95577  ? 30  ASN A CA   1 
ATOM   414  C  C    . ASN A 1 50  ? -6.09944  4.34947   -27.51380 1.000 25.83695  ? 30  ASN A C    1 
ATOM   415  O  O    . ASN A 1 50  ? -6.37805  5.47930   -27.95777 1.000 26.05070  ? 30  ASN A O    1 
ATOM   416  C  CB   . ASN A 1 50  ? -7.96247  3.44690   -26.15405 1.000 26.85793  ? 30  ASN A CB   1 
ATOM   417  C  CG   . ASN A 1 50  ? -9.22860  2.63530   -26.11828 1.000 26.40419  ? 30  ASN A CG   1 
ATOM   418  O  OD1  . ASN A 1 50  ? -10.24409 3.03702   -26.66855 1.000 30.91983  ? 30  ASN A OD1  1 
ATOM   419  N  ND2  . ASN A 1 50  ? -9.18317  1.50104   -25.47341 1.000 28.14922  ? 30  ASN A ND2  1 
ATOM   420  H  H    . ASN A 1 50  ? -6.10209  1.67643   -26.99387 1.000 28.69991  ? 30  ASN A H    1 
ATOM   421  H  HA   . ASN A 1 50  ? -7.72358  3.39862   -28.25050 1.000 28.77069  ? 30  ASN A HA   1 
ATOM   422  H  HB2  . ASN A 1 50  ? -7.40689  3.16907   -25.40903 1.000 32.25327  ? 30  ASN A HB2  1 
ATOM   423  H  HB3  . ASN A 1 50  ? -8.20262  4.38181   -26.05826 1.000 32.25327  ? 30  ASN A HB3  1 
ATOM   424  H  HD21 . ASN A 1 50  ? -9.88371  1.00434   -25.42715 1.000 33.80283  ? 30  ASN A HD21 1 
ATOM   425  H  HD22 . ASN A 1 50  ? -8.45271  1.25057   -25.09487 1.000 33.80283  ? 30  ASN A HD22 1 
ATOM   426  N  N    . GLN A 1 51  ? -4.88402  4.04455   -27.03056 1.000 25.60488  ? 31  GLN A N    1 
ATOM   427  C  CA   . GLN A 1 51  ? -3.79950  5.02145   -27.04251 1.000 24.26384  ? 31  GLN A CA   1 
ATOM   428  C  C    . GLN A 1 51  ? -2.48686  4.25399   -26.99933 1.000 19.69043  ? 31  GLN A C    1 
ATOM   429  O  O    . GLN A 1 51  ? -1.89377  4.07351   -25.92905 1.000 22.02441  ? 31  GLN A O    1 
ATOM   430  C  CB   . GLN A 1 51  ? -3.86967  5.99497   -25.87053 1.000 25.74658  ? 31  GLN A CB   1 
ATOM   431  C  CG   . GLN A 1 51  ? -2.96768  7.23799   -26.09228 1.000 28.98723  ? 31  GLN A CG   1 
ATOM   432  C  CD   . GLN A 1 51  ? -2.82505  8.13369   -24.86843 1.000 37.95714  ? 31  GLN A CD   1 
ATOM   433  O  OE1  . GLN A 1 51  ? -2.77973  7.66381   -23.72924 1.000 34.74476  ? 31  GLN A OE1  1 
ATOM   434  N  NE2  . GLN A 1 51  ? -2.70730  9.43599   -25.10506 1.000 39.07613  ? 31  GLN A NE2  1 
ATOM   435  H  H    . GLN A 1 51  ? -4.67067  3.28232   -26.69428 1.000 30.74962  ? 31  GLN A H    1 
ATOM   436  H  HA   . GLN A 1 51  ? -3.86223  5.55855   -27.84780 1.000 29.14037  ? 31  GLN A HA   1 
ATOM   437  H  HB2  . GLN A 1 51  ? -4.78453  6.29903   -25.76333 1.000 30.91965  ? 31  GLN A HB2  1 
ATOM   438  H  HB3  . GLN A 1 51  ? -3.57309  5.54468   -25.06419 1.000 30.91965  ? 31  GLN A HB3  1 
ATOM   439  H  HG2  . GLN A 1 51  ? -2.07974  6.93677   -26.34074 1.000 34.80844  ? 31  GLN A HG2  1 
ATOM   440  H  HG3  . GLN A 1 51  ? -3.34788  7.77404   -26.80572 1.000 34.80844  ? 31  GLN A HG3  1 
ATOM   441  H  HE21 . GLN A 1 51  ? -2.71445  9.72846   -25.91377 1.000 46.91511  ? 31  GLN A HE21 1 
ATOM   442  H  HE22 . GLN A 1 51  ? -2.62395  9.98634   -24.44950 1.000 46.91511  ? 31  GLN A HE22 1 
ATOM   443  N  N    . PRO A 1 52  ? -2.06738  3.71263   -28.14640 1.000 21.63946  ? 32  PRO A N    1 
ATOM   444  C  CA   . PRO A 1 52  ? -0.96319  2.73163   -28.13653 1.000 21.04839  ? 32  PRO A CA   1 
ATOM   445  C  C    . PRO A 1 52  ? 0.31572   3.27084   -27.50773 1.000 21.39351  ? 32  PRO A C    1 
ATOM   446  O  O    . PRO A 1 52  ? 1.08966   2.52133   -26.89585 1.000 20.60533  ? 32  PRO A O    1 
ATOM   447  C  CB   . PRO A 1 52  ? -0.78622  2.41530   -29.63950 1.000 24.61127  ? 32  PRO A CB   1 
ATOM   448  C  CG   . PRO A 1 52  ? -2.11636  2.71274   -30.25054 1.000 28.25269  ? 32  PRO A CG   1 
ATOM   449  C  CD   . PRO A 1 52  ? -2.72928  3.82836   -29.46531 1.000 25.47147  ? 32  PRO A CD   1 
ATOM   450  H  HA   . PRO A 1 52  ? -1.23044  1.92777   -27.66400 1.000 25.28183  ? 32  PRO A HA   1 
ATOM   451  H  HB2  . PRO A 1 52  ? -0.09516  2.98120   -30.01778 1.000 29.55728  ? 32  PRO A HB2  1 
ATOM   452  H  HB3  . PRO A 1 52  ? -0.55087  1.48150   -29.75579 1.000 29.55728  ? 32  PRO A HB3  1 
ATOM   453  H  HG2  . PRO A 1 52  ? -1.99252  2.97857   -31.17515 1.000 33.92699  ? 32  PRO A HG2  1 
ATOM   454  H  HG3  . PRO A 1 52  ? -2.67473  1.92088   -30.20495 1.000 33.92699  ? 32  PRO A HG3  1 
ATOM   455  H  HD2  . PRO A 1 52  ? -2.53691  4.68632   -29.87495 1.000 30.58953  ? 32  PRO A HD2  1 
ATOM   456  H  HD3  . PRO A 1 52  ? -3.68821  3.70757   -29.38305 1.000 30.58953  ? 32  PRO A HD3  1 
ATOM   457  N  N    . VAL A 1 53  ? 0.63710   4.53436   -27.74809 1.000 19.74741  ? 33  VAL A N    1 
ATOM   458  C  CA   . VAL A 1 53  ? 1.69236   5.22205   -27.02755 1.000 21.89592  ? 33  VAL A CA   1 
ATOM   459  C  C    . VAL A 1 53  ? 0.98587   5.99157   -25.91690 1.000 20.36437  ? 33  VAL A C    1 
ATOM   460  O  O    . VAL A 1 53  ? 0.46456   7.10775   -26.09618 1.000 22.66356  ? 33  VAL A O    1 
ATOM   461  C  CB   . VAL A 1 53  ? 2.53736   6.09153   -27.95000 1.000 22.05061  ? 33  VAL A CB   1 
ATOM   462  C  CG1  . VAL A 1 53  ? 3.62913   6.80330   -27.14903 1.000 22.53664  ? 33  VAL A CG1  1 
ATOM   463  C  CG2  . VAL A 1 53  ? 3.17073   5.17687   -29.04407 1.000 22.37273  ? 33  VAL A CG2  1 
ATOM   464  H  H    . VAL A 1 53  ? 0.24778   5.02405   -28.33820 1.000 23.72066  ? 33  VAL A H    1 
ATOM   465  H  HA   . VAL A 1 53  ? 2.29419   4.58519   -26.61150 1.000 26.29886  ? 33  VAL A HA   1 
ATOM   466  H  HB   . VAL A 1 53  ? 1.98901   6.77120   -28.37222 1.000 26.48450  ? 33  VAL A HB   1 
ATOM   467  H  HG11 . VAL A 1 53  ? 4.20859   7.28265   -27.76168 1.000 27.06774  ? 33  VAL A HG11 1 
ATOM   468  H  HG12 . VAL A 1 53  ? 3.21325   7.42545   -26.53188 1.000 27.06774  ? 33  VAL A HG12 1 
ATOM   469  H  HG13 . VAL A 1 53  ? 4.14171   6.14260   -26.65746 1.000 27.06774  ? 33  VAL A HG13 1 
ATOM   470  H  HG21 . VAL A 1 53  ? 3.78637   5.70303   -29.57795 1.000 26.87103  ? 33  VAL A HG21 1 
ATOM   471  H  HG22 . VAL A 1 53  ? 3.64572   4.44995   -28.61177 1.000 26.87103  ? 33  VAL A HG22 1 
ATOM   472  H  HG23 . VAL A 1 53  ? 2.46467   4.82225   -29.60676 1.000 26.87103  ? 33  VAL A HG23 1 
ATOM   473  N  N    . PHE A 1 54  ? 0.91577   5.32188   -24.75933 1.000 22.59335  ? 34  PHE A N    1 
ATOM   474  C  CA   . PHE A 1 54  ? 0.07570   5.68968   -23.63076 1.000 22.14507  ? 34  PHE A CA   1 
ATOM   475  C  C    . PHE A 1 54  ? 0.80762   6.65894   -22.72334 1.000 22.67464  ? 34  PHE A C    1 
ATOM   476  O  O    . PHE A 1 54  ? 2.01394   6.54257   -22.51752 1.000 24.69792  ? 34  PHE A O    1 
ATOM   477  C  CB   . PHE A 1 54  ? -0.30316  4.38268   -22.89301 1.000 21.19149  ? 34  PHE A CB   1 
ATOM   478  C  CG   . PHE A 1 54  ? -1.12109  4.56248   -21.65289 1.000 22.62903  ? 34  PHE A CG   1 
ATOM   479  C  CD1  . PHE A 1 54  ? -2.44125  4.91363   -21.77273 1.000 24.46022  ? 34  PHE A CD1  1 
ATOM   480  C  CD2  . PHE A 1 54  ? -0.59478  4.28287   -20.40198 1.000 23.69552  ? 34  PHE A CD2  1 
ATOM   481  C  CE1  . PHE A 1 54  ? -3.23520  5.07557   -20.64250 1.000 28.09213  ? 34  PHE A CE1  1 
ATOM   482  C  CE2  . PHE A 1 54  ? -1.37478  4.41212   -19.27570 1.000 25.69127  ? 34  PHE A CE2  1 
ATOM   483  C  CZ   . PHE A 1 54  ? -2.70151  4.81525   -19.41411 1.000 25.22418  ? 34  PHE A CZ   1 
ATOM   484  H  H    . PHE A 1 54  ? 1.37417   4.61158   -24.60141 1.000 27.13578  ? 34  PHE A H    1 
ATOM   485  H  HA   . PHE A 1 54  ? -0.73534  6.14454   -23.90684 1.000 26.59785  ? 34  PHE A HA   1 
ATOM   486  H  HB2  . PHE A 1 54  ? -0.81613  3.82649   -23.49997 1.000 25.45355  ? 34  PHE A HB2  1 
ATOM   487  H  HB3  . PHE A 1 54  ? 0.51447   3.92786   -22.63706 1.000 25.45355  ? 34  PHE A HB3  1 
ATOM   488  H  HD1  . PHE A 1 54  ? -2.80872  5.04458   -22.61696 1.000 29.37603  ? 34  PHE A HD1  1 
ATOM   489  H  HD2  . PHE A 1 54  ? 0.28973   4.00657   -20.32320 1.000 28.45839  ? 34  PHE A HD2  1 
ATOM   490  H  HE1  . PHE A 1 54  ? -4.11780  5.35743   -20.72288 1.000 33.73432  ? 34  PHE A HE1  1 
ATOM   491  H  HE2  . PHE A 1 54  ? -1.02157  4.23301   -18.43424 1.000 30.85329  ? 34  PHE A HE2  1 
ATOM   492  H  HZ   . PHE A 1 54  ? -3.23228  4.90844   -18.65615 1.000 30.29278  ? 34  PHE A HZ   1 
ATOM   493  N  N    . ARG A 1 55  ? 0.06672   7.58425   -22.12810 1.000 24.35594  ? 35  ARG A N    1 
ATOM   494  C  CA   . ARG A 1 55  ? 0.59353   8.33646   -20.98796 1.000 22.86410  ? 35  ARG A CA   1 
ATOM   495  C  C    . ARG A 1 55  ? -0.14922  7.94788   -19.71936 1.000 24.69332  ? 35  ARG A C    1 
ATOM   496  O  O    . ARG A 1 55  ? -1.38539  7.99101   -19.69080 1.000 26.47746  ? 35  ARG A O    1 
ATOM   497  C  CB   . ARG A 1 55  ? 0.46481   9.83881   -21.20214 1.000 27.49522  ? 35  ARG A CB   1 
ATOM   498  C  CG   . ARG A 1 55  ? 1.43396   10.34868  -22.29162 1.000 29.69214  ? 35  ARG A CG   1 
ATOM   499  C  CD   . ARG A 1 55  ? 1.63526   11.82072  -22.17896 1.000 29.24706  ? 35  ARG A CD   1 
ATOM   500  N  NE   . ARG A 1 55  ? 2.51148   12.33091  -23.22470 1.000 29.83668  ? 35  ARG A NE   1 
ATOM   501  C  CZ   . ARG A 1 55  ? 3.82574   12.43758  -23.11302 1.000 27.94758  ? 35  ARG A CZ   1 
ATOM   502  N  NH1  . ARG A 1 55  ? 4.46161   12.07565  -22.01352 1.000 27.16667  ? 35  ARG A NH1  1 
ATOM   503  N  NH2  . ARG A 1 55  ? 4.52186   12.95385  -24.12324 1.000 27.69168  ? 35  ARG A NH2  1 
ATOM   504  H  H    . ARG A 1 55  ? -0.73412  7.79397   -22.36105 1.000 29.25089  ? 35  ARG A H    1 
ATOM   505  H  HA   . ARG A 1 55  ? 1.53173   8.11367   -20.88282 1.000 27.46068  ? 35  ARG A HA   1 
ATOM   506  H  HB2  . ARG A 1 55  ? -0.44130  10.04517  -21.48010 1.000 33.01803  ? 35  ARG A HB2  1 
ATOM   507  H  HB3  . ARG A 1 55  ? 0.67022   10.29826  -20.37291 1.000 33.01803  ? 35  ARG A HB3  1 
ATOM   508  H  HG2  . ARG A 1 55  ? 2.29417   9.91229   -22.18919 1.000 35.65433  ? 35  ARG A HG2  1 
ATOM   509  H  HG3  . ARG A 1 55  ? 1.06603   10.15515  -23.16802 1.000 35.65433  ? 35  ARG A HG3  1 
ATOM   510  H  HD2  . ARG A 1 55  ? 0.77777   12.26741  -22.25696 1.000 35.12023  ? 35  ARG A HD2  1 
ATOM   511  H  HD3  . ARG A 1 55  ? 2.03799   12.02337  -21.32009 1.000 35.12023  ? 35  ARG A HD3  1 
ATOM   512  H  HE   . ARG A 1 55  ? 2.15038   12.57956  -23.96455 1.000 35.82778  ? 35  ARG A HE   1 
ATOM   513  H  HH11 . ARG A 1 55  ? 4.02067   11.76085  -21.34563 1.000 32.62376  ? 35  ARG A HH11 1 
ATOM   514  H  HH12 . ARG A 1 55  ? 5.31661   12.15477  -21.96544 1.000 32.62376  ? 35  ARG A HH12 1 
ATOM   515  H  HH21 . ARG A 1 55  ? 4.11702   13.21282  -24.83643 1.000 33.25378  ? 35  ARG A HH21 1 
ATOM   516  H  HH22 . ARG A 1 55  ? 5.37649   13.02844  -24.06277 1.000 33.25378  ? 35  ARG A HH22 1 
ATOM   517  N  N    . ASP A 1 56  ? 0.60939   7.60702   -18.67465 1.000 25.65612  ? 36  ASP A N    1 
ATOM   518  C  CA   . ASP A 1 56  ? -0.00071  7.13748   -17.43248 1.000 25.08542  ? 36  ASP A CA   1 
ATOM   519  C  C    . ASP A 1 56  ? -0.47677  8.33331   -16.59671 1.000 25.06579  ? 36  ASP A C    1 
ATOM   520  O  O    . ASP A 1 56  ? -0.52503  9.48815   -17.03771 1.000 27.56248  ? 36  ASP A O    1 
ATOM   521  C  CB   . ASP A 1 56  ? 0.94241   6.20340   -16.66230 1.000 24.83919  ? 36  ASP A CB   1 
ATOM   522  C  CG   . ASP A 1 56  ? 2.07942   6.90212   -15.93989 1.000 26.27692  ? 36  ASP A CG   1 
ATOM   523  O  OD1  . ASP A 1 56  ? 2.18545   8.15289   -15.90420 1.000 26.46363  ? 36  ASP A OD1  1 
ATOM   524  O  OD2  . ASP A 1 56  ? 2.87611   6.13910   -15.35247 1.000 26.95702  ? 36  ASP A OD2  1 
ATOM   525  H  H    . ASP A 1 56  ? 1.46870   7.63916   -18.66240 1.000 30.81110  ? 36  ASP A H    1 
ATOM   526  H  HA   . ASP A 1 56  ? -0.78146  6.61494   -17.67389 1.000 30.12627  ? 36  ASP A HA   1 
ATOM   527  H  HB2  . ASP A 1 56  ? 0.42525   5.72380   -15.99639 1.000 29.83078  ? 36  ASP A HB2  1 
ATOM   528  H  HB3  . ASP A 1 56  ? 1.33685   5.57771   -17.28986 1.000 29.83078  ? 36  ASP A HB3  1 
ATOM   529  N  N    . ARG A 1 57  ? -0.88103  8.05421   -15.35939 1.000 27.40920  ? 37  ARG A N    1 
ATOM   530  C  CA   A ARG A 1 57  ? -1.51475  9.09290   -14.55131 0.502 29.06563  ? 37  ARG A CA   1 
ATOM   531  C  CA   B ARG A 1 57  ? -1.52640  9.11462   -14.59302 0.498 29.06026  ? 37  ARG A CA   1 
ATOM   532  C  C    . ARG A 1 57  ? -0.56134  10.23208  -14.21643 1.000 29.23611  ? 37  ARG A C    1 
ATOM   533  O  O    . ARG A 1 57  ? -1.01540  11.34599  -13.90865 1.000 35.63633  ? 37  ARG A O    1 
ATOM   534  C  CB   A ARG A 1 57  ? -2.07802  8.48891   -13.26342 0.502 33.97187  ? 37  ARG A CB   1 
ATOM   535  C  CB   B ARG A 1 57  ? -2.20457  8.54356   -13.34678 0.498 33.95752  ? 37  ARG A CB   1 
ATOM   536  C  CG   A ARG A 1 57  ? -1.01545  8.11524   -12.24692 0.502 33.03118  ? 37  ARG A CG   1 
ATOM   537  C  CG   B ARG A 1 57  ? -1.28115  8.04906   -12.25269 0.498 33.21070  ? 37  ARG A CG   1 
ATOM   538  C  CD   A ARG A 1 57  ? -1.60749  7.33885   -11.06703 0.502 37.82713  ? 37  ARG A CD   1 
ATOM   539  C  CD   B ARG A 1 57  ? -2.10254  7.28483   -11.20549 0.498 37.71039  ? 37  ARG A CD   1 
ATOM   540  N  NE   A ARG A 1 57  ? -2.64521  8.09876   -10.38235 0.502 35.92641  ? 37  ARG A NE   1 
ATOM   541  N  NE   B ARG A 1 57  ? -1.31930  6.81583   -10.07137 0.498 39.80326  ? 37  ARG A NE   1 
ATOM   542  C  CZ   A ARG A 1 57  ? -2.41385  8.99134   -9.42807  0.502 40.93612  ? 37  ARG A CZ   1 
ATOM   543  C  CZ   B ARG A 1 57  ? -1.63850  5.77236   -9.31802  0.498 37.02900  ? 37  ARG A CZ   1 
ATOM   544  N  NH1  A ARG A 1 57  ? -1.18578  9.25449   -9.00860  0.502 40.53184  ? 37  ARG A NH1  1 
ATOM   545  N  NH1  B ARG A 1 57  ? -2.66487  4.99346   -9.61260  0.498 38.16437  ? 37  ARG A NH1  1 
ATOM   546  N  NH2  A ARG A 1 57  ? -3.44028  9.63237   -8.87814  0.502 41.23951  ? 37  ARG A NH2  1 
ATOM   547  N  NH2  B ARG A 1 57  ? -0.91135  5.50735   -8.24093  0.498 38.99416  ? 37  ARG A NH2  1 
ATOM   548  H  H    A ARG A 1 57  ? -0.80222  7.28993   -14.97305 0.502 32.91480  ? 37  ARG A H    1 
ATOM   549  H  H    B ARG A 1 57  ? -0.79741  7.29671   -14.96090 0.498 32.91480  ? 37  ARG A H    1 
ATOM   550  H  HA   A ARG A 1 57  ? -2.25443  9.46523   -15.05642 0.502 34.90252  ? 37  ARG A HA   1 
ATOM   551  H  HA   B ARG A 1 57  ? -2.22397  9.50717   -15.14092 0.498 34.89608  ? 37  ARG A HA   1 
ATOM   552  H  HB2  A ARG A 1 57  ? -2.66994  9.13583   -12.84867 0.502 40.79000  ? 37  ARG A HB2  1 
ATOM   553  H  HB2  B ARG A 1 57  ? -2.76048  9.23788   -12.95975 0.498 40.77279  ? 37  ARG A HB2  1 
ATOM   554  H  HB3  A ARG A 1 57  ? -2.57066  7.68360   -13.48631 0.502 40.79000  ? 37  ARG A HB3  1 
ATOM   555  H  HB3  B ARG A 1 57  ? -2.75396  7.79185   -13.61882 0.498 40.77279  ? 37  ARG A HB3  1 
ATOM   556  H  HG2  A ARG A 1 57  ? -0.34656  7.55682   -12.67315 0.502 39.66118  ? 37  ARG A HG2  1 
ATOM   557  H  HG2  B ARG A 1 57  ? -0.61568  7.45125   -12.62775 0.498 39.87660  ? 37  ARG A HG2  1 
ATOM   558  H  HG3  A ARG A 1 57  ? -0.60300  8.92296   -11.90288 0.502 39.66118  ? 37  ARG A HG3  1 
ATOM   559  H  HG3  B ARG A 1 57  ? -0.84611  8.80194   -11.82279 0.498 39.87660  ? 37  ARG A HG3  1 
ATOM   560  H  HD2  A ARG A 1 57  ? -2.00031  6.51373   -11.39227 0.502 45.41631  ? 37  ARG A HD2  1 
ATOM   561  H  HD2  B ARG A 1 57  ? -2.79534  7.87129   -10.86344 0.498 45.27623  ? 37  ARG A HD2  1 
ATOM   562  H  HD3  A ARG A 1 57  ? -0.90414  7.14236   -10.42860 0.502 45.41631  ? 37  ARG A HD3  1 
ATOM   563  H  HD3  B ARG A 1 57  ? -2.50331  6.50929   -11.62835 0.498 45.27623  ? 37  ARG A HD3  1 
ATOM   564  H  HE   A ARG A 1 57  ? -3.46219  7.95951   -10.61204 0.502 43.13546  ? 37  ARG A HE   1 
ATOM   565  H  HE   B ARG A 1 57  ? -0.60003  7.24516   -9.87661  0.498 47.78768  ? 37  ARG A HE   1 
ATOM   566  H  HH11 A ARG A 1 57  ? -0.51530  8.84297   -9.35602  0.502 48.66197  ? 37  ARG A HH11 1 
ATOM   567  H  HH11 B ARG A 1 57  ? -3.14416  5.15814   -10.30740 0.498 45.82100  ? 37  ARG A HH11 1 
ATOM   568  H  HH12 A ARG A 1 57  ? -1.05866  9.83692   -8.38875  0.502 48.66197  ? 37  ARG A HH12 1 
ATOM   569  H  HH12 B ARG A 1 57  ? -2.85341  4.32196   -9.10946  0.498 45.82100  ? 37  ARG A HH12 1 
ATOM   570  H  HH21 A ARG A 1 57  ? -4.24193  9.46647   -9.14166  0.502 49.51118  ? 37  ARG A HH21 1 
ATOM   571  H  HH21 B ARG A 1 57  ? -0.24292  6.00943   -8.03917  0.498 46.81675  ? 37  ARG A HH21 1 
ATOM   572  H  HH22 A ARG A 1 57  ? -3.30272  10.21301  -8.25884  0.502 49.51118  ? 37  ARG A HH22 1 
ATOM   573  H  HH22 B ARG A 1 57  ? -1.10829  4.83343   -7.74430  0.498 46.81675  ? 37  ARG A HH22 1 
ATOM   574  N  N    . ASN A 1 58  ? 0.74021   9.98830   -14.27860 1.000 29.65850  ? 38  ASN A N    1 
ATOM   575  C  CA   . ASN A 1 58  ? 1.75899   10.99800  -14.03346 1.000 29.25705  ? 38  ASN A CA   1 
ATOM   576  C  C    . ASN A 1 58  ? 2.36580   11.57070  -15.32452 1.000 31.99198  ? 38  ASN A C    1 
ATOM   577  O  O    . ASN A 1 58  ? 3.32692   12.34169  -15.25922 1.000 33.07367  ? 38  ASN A O    1 
ATOM   578  C  CB   . ASN A 1 58  ? 2.87253   10.41681  -13.17962 1.000 29.96370  ? 38  ASN A CB   1 
ATOM   579  C  CG   . ASN A 1 58  ? 2.37116   9.92552   -11.84413 1.000 31.50213  ? 38  ASN A CG   1 
ATOM   580  O  OD1  . ASN A 1 58  ? 2.65467   8.80556   -11.41879 1.000 37.88574  ? 38  ASN A OD1  1 
ATOM   581  N  ND2  . ASN A 1 58  ? 1.58991   10.74112  -11.21204 1.000 32.70701  ? 38  ASN A ND2  1 
ATOM   582  H  H    . ASN A 1 58  ? 1.07005   9.21699   -14.46801 1.000 35.61397  ? 38  ASN A H    1 
ATOM   583  H  HA   . ASN A 1 58  ? 1.34170   11.72785  -13.54963 1.000 35.13222  ? 38  ASN A HA   1 
ATOM   584  H  HB2  . ASN A 1 58  ? 3.27289   9.66674   -13.64654 1.000 35.98020  ? 38  ASN A HB2  1 
ATOM   585  H  HB3  . ASN A 1 58  ? 3.54015   11.10176  -13.01829 1.000 35.98020  ? 38  ASN A HB3  1 
ATOM   586  H  HD21 . ASN A 1 58  ? 1.26926   10.52173  -10.44481 1.000 39.27218  ? 38  ASN A HD21 1 
ATOM   587  H  HD22 . ASN A 1 58  ? 1.39145   11.50247  -11.55927 1.000 39.27218  ? 38  ASN A HD22 1 
ATOM   588  N  N    . GLY A 1 59  ? 1.83381   11.20483  -16.47559 1.000 28.74024  ? 39  GLY A N    1 
ATOM   589  C  CA   . GLY A 1 59  ? 2.31290   11.65960  -17.76453 1.000 29.00655  ? 39  GLY A CA   1 
ATOM   590  C  C    . GLY A 1 59  ? 3.43830   10.85202  -18.36786 1.000 27.41166  ? 39  GLY A C    1 
ATOM   591  O  O    . GLY A 1 59  ? 3.98506   11.27096  -19.39878 1.000 27.10187  ? 39  GLY A O    1 
ATOM   592  H  H    . GLY A 1 59  ? 1.16385   10.66940  -16.53934 1.000 34.51205  ? 39  GLY A H    1 
ATOM   593  H  HA2  . GLY A 1 59  ? 1.57249   11.64234  -18.39094 1.000 34.83162  ? 39  GLY A HA2  1 
ATOM   594  H  HA3  . GLY A 1 59  ? 2.62618   12.57284  -17.67099 1.000 34.83162  ? 39  GLY A HA3  1 
ATOM   595  N  N    . LEU A 1 60  ? 3.83624   9.74860   -17.74178 1.000 24.26412  ? 40  LEU A N    1 
ATOM   596  C  CA   . LEU A 1 60  ? 4.92314   8.91412   -18.25505 1.000 23.80781  ? 40  LEU A CA   1 
ATOM   597  C  C    . LEU A 1 60  ? 4.46234   8.17913   -19.51920 1.000 23.91885  ? 40  LEU A C    1 
ATOM   598  O  O    . LEU A 1 60  ? 3.42440   7.50223   -19.52511 1.000 24.31873  ? 40  LEU A O    1 
ATOM   599  C  CB   . LEU A 1 60  ? 5.38044   7.90596   -17.18930 1.000 24.80294  ? 40  LEU A CB   1 
ATOM   600  C  CG   . LEU A 1 60  ? 6.47955   6.92183   -17.59047 1.000 27.73811  ? 40  LEU A CG   1 
ATOM   601  C  CD1  . LEU A 1 60  ? 7.74755   7.63624   -18.04530 1.000 32.87066  ? 40  LEU A CD1  1 
ATOM   602  C  CD2  . LEU A 1 60  ? 6.77935   6.00712   -16.42332 1.000 32.00846  ? 40  LEU A CD2  1 
ATOM   603  H  H    . LEU A 1 60  ? 3.49134   9.45606   -17.01030 1.000 29.14071  ? 40  LEU A H    1 
ATOM   604  H  HA   . LEU A 1 60  ? 5.68207   9.47510   -18.47916 1.000 28.59313  ? 40  LEU A HA   1 
ATOM   605  H  HB2  . LEU A 1 60  ? 5.71327   8.40675   -16.42816 1.000 29.78730  ? 40  LEU A HB2  1 
ATOM   606  H  HB3  . LEU A 1 60  ? 4.60983   7.37806   -16.92780 1.000 29.78730  ? 40  LEU A HB3  1 
ATOM   607  H  HG   . LEU A 1 60  ? 6.16946   6.39656   -18.34468 1.000 33.30949  ? 40  LEU A HG   1 
ATOM   608  H  HD11 . LEU A 1 60  ? 8.44664   6.97899   -18.18743 1.000 39.46855  ? 40  LEU A HD11 1 
ATOM   609  H  HD12 . LEU A 1 60  ? 7.56447   8.10857   -18.87252 1.000 39.46855  ? 40  LEU A HD12 1 
ATOM   610  H  HD13 . LEU A 1 60  ? 8.01937   8.26504   -17.35855 1.000 39.46855  ? 40  LEU A HD13 1 
ATOM   611  H  HD21 . LEU A 1 60  ? 7.46320   5.37192   -16.68745 1.000 38.43391  ? 40  LEU A HD21 1 
ATOM   612  H  HD22 . LEU A 1 60  ? 7.09399   6.54054   -15.67675 1.000 38.43391  ? 40  LEU A HD22 1 
ATOM   613  H  HD23 . LEU A 1 60  ? 5.96860   5.53610   -16.17487 1.000 38.43391  ? 40  LEU A HD23 1 
ATOM   614  N  N    . ALA A 1 61  ? 5.23913   8.32911   -20.59198 1.000 23.67664  ? 41  ALA A N    1 
ATOM   615  C  CA   . ALA A 1 61  ? 4.91788   7.73368   -21.88860 1.000 22.46363  ? 41  ALA A CA   1 
ATOM   616  C  C    . ALA A 1 61  ? 5.38003   6.28217   -21.97847 1.000 20.72536  ? 41  ALA A C    1 
ATOM   617  O  O    . ALA A 1 61  ? 6.41454   5.90430   -21.43194 1.000 23.21125  ? 41  ALA A O    1 
ATOM   618  C  CB   . ALA A 1 61  ? 5.60118   8.50405   -23.00177 1.000 24.65213  ? 41  ALA A CB   1 
ATOM   619  H  H    . ALA A 1 61  ? 5.97168   8.77961   -20.59539 1.000 28.43574  ? 41  ALA A H    1 
ATOM   620  H  HA   . ALA A 1 61  ? 3.95489   7.76171   -22.00153 1.000 26.98011  ? 41  ALA A HA   1 
ATOM   621  H  HB1  . ALA A 1 61  ? 5.38552   8.08903   -23.85157 1.000 29.60631  ? 41  ALA A HB1  1 
ATOM   622  H  HB2  . ALA A 1 61  ? 5.28474   9.42093   -22.99169 1.000 29.60631  ? 41  ALA A HB2  1 
ATOM   623  H  HB3  . ALA A 1 61  ? 6.56017   8.48350   -22.85754 1.000 29.60631  ? 41  ALA A HB3  1 
ATOM   624  N  N    . ALA A 1 62  ? 4.59766   5.46409   -22.68090 1.000 19.68375  ? 42  ALA A N    1 
ATOM   625  C  CA   . ALA A 1 62  ? 4.89608   4.03425   -22.78219 1.000 19.09878  ? 42  ALA A CA   1 
ATOM   626  C  C    . ALA A 1 62  ? 4.34093   3.46963   -24.08296 1.000 22.66935  ? 42  ALA A C    1 
ATOM   627  O  O    . ALA A 1 62  ? 3.16588   3.65278   -24.40784 1.000 22.38074  ? 42  ALA A O    1 
ATOM   628  C  CB   . ALA A 1 62  ? 4.32646   3.25340   -21.59471 1.000 22.74025  ? 42  ALA A CB   1 
ATOM   629  H  H    . ALA A 1 62  ? 3.89182   5.71047   -23.10596 1.000 23.64426  ? 42  ALA A H    1 
ATOM   630  H  HA   . ALA A 1 62  ? 5.86016   3.92822   -22.79631 1.000 22.94230  ? 42  ALA A HA   1 
ATOM   631  H  HB1  . ALA A 1 62  ? 4.52200   2.31078   -21.71356 1.000 27.31207  ? 42  ALA A HB1  1 
ATOM   632  H  HB2  . ALA A 1 62  ? 4.73807   3.57618   -20.77783 1.000 27.31207  ? 42  ALA A HB2  1 
ATOM   633  H  HB3  . ALA A 1 62  ? 3.36684   3.39009   -21.55796 1.000 27.31207  ? 42  ALA A HB3  1 
ATOM   634  N  N    . ALA A 1 63  ? 5.18115   2.74548   -24.80490 1.000 19.02653  ? 43  ALA A N    1 
ATOM   635  C  CA   . ALA A 1 63  ? 4.81215   2.06049   -26.03835 1.000 17.97592  ? 43  ALA A CA   1 
ATOM   636  C  C    . ALA A 1 63  ? 4.24245   0.69382   -25.67061 1.000 18.16289  ? 43  ALA A C    1 
ATOM   637  O  O    . ALA A 1 63  ? 4.94881   -0.15877  -25.10561 1.000 18.86877  ? 43  ALA A O    1 
ATOM   638  C  CB   . ALA A 1 63  ? 6.04176   1.95183   -26.93569 1.000 20.24556  ? 43  ALA A CB   1 
ATOM   639  H  H    . ALA A 1 63  ? 6.00679   2.62910   -24.59423 1.000 22.85559  ? 43  ALA A H    1 
ATOM   640  H  HA   . ALA A 1 63  ? 4.12303   2.54652   -26.51771 1.000 21.59487  ? 43  ALA A HA   1 
ATOM   641  H  HB1  . ALA A 1 63  ? 5.80563   1.45810   -27.73655 1.000 24.31844  ? 43  ALA A HB1  1 
ATOM   642  H  HB2  . ALA A 1 63  ? 6.33946   2.84403   -27.17287 1.000 24.31844  ? 43  ALA A HB2  1 
ATOM   643  H  HB3  . ALA A 1 63  ? 6.74353   1.48590   -26.45472 1.000 24.31844  ? 43  ALA A HB3  1 
ATOM   644  N  N    . SER A 1 64  ? 2.93745   0.50048   -25.95442 1.000 18.66283  ? 44  SER A N    1 
ATOM   645  C  CA   . SER A 1 64  ? 2.21265   -0.70188  -25.52472 1.000 18.00803  ? 44  SER A CA   1 
ATOM   646  C  C    . SER A 1 64  ? 2.00102   -1.73474  -26.62575 1.000 20.57134  ? 44  SER A C    1 
ATOM   647  O  O    . SER A 1 64  ? 1.71208   -2.89946  -26.31540 1.000 19.98982  ? 44  SER A O    1 
ATOM   648  C  CB   . SER A 1 64  ? 0.84905   -0.32476  -24.95732 1.000 19.62223  ? 44  SER A CB   1 
ATOM   649  O  OG   . SER A 1 64  ? -0.06114  0.14618   -25.94010 1.000 20.45451  ? 44  SER A OG   1 
ATOM   650  H  H    . SER A 1 64  ? 2.45302   1.05671   -26.39661 1.000 22.41916  ? 44  SER A H    1 
ATOM   651  H  HA   . SER A 1 64  ? 2.73501   -1.12327  -24.82438 1.000 21.63340  ? 44  SER A HA   1 
ATOM   652  H  HB2  . SER A 1 64  ? 0.46528   -1.11039  -24.53731 1.000 23.57044  ? 44  SER A HB2  1 
ATOM   653  H  HB3  . SER A 1 64  ? 0.97574   0.37542   -24.29807 1.000 23.57044  ? 44  SER A HB3  1 
ATOM   654  H  HG   . SER A 1 64  ? 0.24913   0.83128   -26.31423 1.000 24.56917  ? 44  SER A HG   1 
ATOM   655  N  N    . THR A 1 65  ? 2.12098   -1.36198  -27.89302 1.000 19.76947  ? 45  THR A N    1 
ATOM   656  C  CA   . THR A 1 65  ? 1.89667   -2.30468  -28.98528 1.000 20.24361  ? 45  THR A CA   1 
ATOM   657  C  C    . THR A 1 65  ? 3.22907   -2.86107  -29.46941 1.000 20.31773  ? 45  THR A C    1 
ATOM   658  O  O    . THR A 1 65  ? 4.29383   -2.22755  -29.33042 1.000 20.70948  ? 45  THR A O    1 
ATOM   659  C  CB   . THR A 1 65  ? 1.20341   -1.63934  -30.16564 1.000 21.47023  ? 45  THR A CB   1 
ATOM   660  O  OG1  . THR A 1 65  ? 2.02668   -0.52772  -30.55998 1.000 22.40240  ? 45  THR A OG1  1 
ATOM   661  C  CG2  . THR A 1 65  ? -0.20341  -1.15887  -29.77472 1.000 24.22102  ? 45  THR A CG2  1 
ATOM   662  H  H    . THR A 1 65  ? 2.33153   -0.56797  -28.14761 1.000 23.74713  ? 45  THR A H    1 
ATOM   663  H  HA   . THR A 1 65  ? 1.33437   -3.02568  -28.66144 1.000 24.31610  ? 45  THR A HA   1 
ATOM   664  H  HB   . THR A 1 65  ? 1.08726   -2.25723  -30.90431 1.000 25.78803  ? 45  THR A HB   1 
ATOM   665  H  HG1  . THR A 1 65  ? 1.72712   -0.18446  -31.26569 1.000 26.90664  ? 45  THR A HG1  1 
ATOM   666  H  HG21 . THR A 1 65  ? -0.59761  -0.65722  -30.50537 1.000 29.08898  ? 45  THR A HG21 1 
ATOM   667  H  HG22 . THR A 1 65  ? -0.77003  -1.92008  -29.57372 1.000 29.08898  ? 45  THR A HG22 1 
ATOM   668  H  HG23 . THR A 1 65  ? -0.15348  -0.58820  -28.99194 1.000 29.08898  ? 45  THR A HG23 1 
ATOM   669  N  N    . TYR A 1 66  ? 3.15783   -4.06036  -30.03900 1.000 19.61208  ? 46  TYR A N    1 
ATOM   670  C  CA   . TYR A 1 66  ? 4.32222   -4.66287  -30.65793 1.000 19.94259  ? 46  TYR A CA   1 
ATOM   671  C  C    . TYR A 1 66  ? 4.90653   -3.75223  -31.72376 1.000 21.06878  ? 46  TYR A C    1 
ATOM   672  O  O    . TYR A 1 66  ? 6.12292   -3.52491  -31.75246 1.000 21.20507  ? 46  TYR A O    1 
ATOM   673  C  CB   . TYR A 1 66  ? 3.92019   -6.00531  -31.24801 1.000 21.00103  ? 46  TYR A CB   1 
ATOM   674  C  CG   . TYR A 1 66  ? 5.01186   -6.93530  -31.73199 1.000 19.56303  ? 46  TYR A CG   1 
ATOM   675  C  CD1  . TYR A 1 66  ? 5.62878   -6.73032  -32.93303 1.000 21.94097  ? 46  TYR A CD1  1 
ATOM   676  C  CD2  . TYR A 1 66  ? 5.37501   -8.04686  -30.97793 1.000 19.81914  ? 46  TYR A CD2  1 
ATOM   677  C  CE1  . TYR A 1 66  ? 6.58768   -7.59589  -33.41173 1.000 22.64910  ? 46  TYR A CE1  1 
ATOM   678  C  CE2  . TYR A 1 66  ? 6.34397   -8.93324  -31.43178 1.000 20.27710  ? 46  TYR A CE2  1 
ATOM   679  C  CZ   . TYR A 1 66  ? 6.94028   -8.70395  -32.65879 1.000 21.96743  ? 46  TYR A CZ   1 
ATOM   680  O  OH   . TYR A 1 66  ? 7.88150   -9.53345  -33.17311 1.000 24.00037  ? 46  TYR A OH   1 
ATOM   681  H  H    . TYR A 1 66  ? 2.44658   -4.54218  -30.07857 1.000 23.55826  ? 46  TYR A H    1 
ATOM   682  H  HA   . TYR A 1 66  ? 5.01134   -4.80988  -29.99130 1.000 23.95487  ? 46  TYR A HA   1 
ATOM   683  H  HB2  . TYR A 1 66  ? 3.42703   -6.48940  -30.56730 1.000 25.22500  ? 46  TYR A HB2  1 
ATOM   684  H  HB3  . TYR A 1 66  ? 3.34777   -5.83089  -32.01143 1.000 25.22500  ? 46  TYR A HB3  1 
ATOM   685  H  HD1  . TYR A 1 66  ? 5.39549   -5.98704  -33.44098 1.000 26.35292  ? 46  TYR A HD1  1 
ATOM   686  H  HD2  . TYR A 1 66  ? 4.96310   -8.19875  -30.15807 1.000 23.80673  ? 46  TYR A HD2  1 
ATOM   687  H  HE1  . TYR A 1 66  ? 6.99459   -7.43777  -34.23291 1.000 27.20268  ? 46  TYR A HE1  1 
ATOM   688  H  HE2  . TYR A 1 66  ? 6.58792   -9.66942  -30.91852 1.000 24.35628  ? 46  TYR A HE2  1 
ATOM   689  H  HH   . TYR A 1 66  ? 8.00489   -10.18374 -32.65591 1.000 28.82421  ? 46  TYR A HH   1 
ATOM   690  N  N    . GLN A 1 67  ? 4.03872   -3.17438  -32.55995 1.000 21.53818  ? 47  GLN A N    1 
ATOM   691  C  CA   . GLN A 1 67  ? 4.51337   -2.29003  -33.61716 1.000 22.82890  ? 47  GLN A CA   1 
ATOM   692  C  C    . GLN A 1 67  ? 5.25406   -1.08288  -33.05683 1.000 21.97614  ? 47  GLN A C    1 
ATOM   693  O  O    . GLN A 1 67  ? 6.30742   -0.70732  -33.58010 1.000 21.54714  ? 47  GLN A O    1 
ATOM   694  C  CB   . GLN A 1 67  ? 3.34269   -1.82695  -34.48990 1.000 26.67305  ? 47  GLN A CB   1 
ATOM   695  C  CG   . GLN A 1 67  ? 3.82210   -1.04365  -35.68981 1.000 28.51738  ? 47  GLN A CG   1 
ATOM   696  C  CD   . GLN A 1 67  ? 4.49292   -1.93634  -36.69178 1.000 39.90992  ? 47  GLN A CD   1 
ATOM   697  O  OE1  . GLN A 1 67  ? 3.88979   -2.90543  -37.16801 1.000 45.27975  ? 47  GLN A OE1  1 
ATOM   698  N  NE2  . GLN A 1 67  ? 5.70903   -1.58505  -37.08575 1.000 41.59118  ? 47  GLN A NE2  1 
ATOM   699  H  H    . GLN A 1 67  ? 3.18538   -3.27810  -32.53442 1.000 25.86958  ? 47  GLN A H    1 
ATOM   700  H  HA   . GLN A 1 67  ? 5.13092   -2.79178  -34.17193 1.000 27.41844  ? 47  GLN A HA   1 
ATOM   701  H  HB2  . GLN A 1 67  ? 2.85292   -2.60199  -34.80665 1.000 32.03142  ? 47  GLN A HB2  1 
ATOM   702  H  HB3  . GLN A 1 67  ? 2.75849   -1.25663  -33.96612 1.000 32.03142  ? 47  GLN A HB3  1 
ATOM   703  H  HG2  . GLN A 1 67  ? 3.06406   -0.61714  -36.11918 1.000 34.24461  ? 47  GLN A HG2  1 
ATOM   704  H  HG3  . GLN A 1 67  ? 4.46082   -0.37289  -35.40167 1.000 34.24461  ? 47  GLN A HG3  1 
ATOM   705  H  HE21 . GLN A 1 67  ? 6.07557   -0.87488  -36.76806 1.000 49.93317  ? 47  GLN A HE21 1 
ATOM   706  H  HE22 . GLN A 1 67  ? 6.13140   -2.06733  -37.65900 1.000 49.93317  ? 47  GLN A HE22 1 
ATOM   707  N  N    . ALA A 1 68  ? 4.71340   -0.44609  -32.01047 1.000 21.40695  ? 48  ALA A N    1 
ATOM   708  C  CA   . ALA A 1 68  ? 5.36701   0.73306   -31.45073 1.000 20.53730  ? 48  ALA A CA   1 
ATOM   709  C  C    . ALA A 1 68  ? 6.69383   0.36530   -30.78801 1.000 20.85399  ? 48  ALA A C    1 
ATOM   710  O  O    . ALA A 1 68  ? 7.67926   1.10777   -30.88897 1.000 21.46545  ? 48  ALA A O    1 
ATOM   711  C  CB   . ALA A 1 68  ? 4.46829   1.42766   -30.43819 1.000 20.95808  ? 48  ALA A CB   1 
ATOM   712  H  H    . ALA A 1 68  ? 3.98374   -0.67444  -31.61670 1.000 25.71210  ? 48  ALA A H    1 
ATOM   713  H  HA   . ALA A 1 68  ? 5.53472   1.35248   -32.17812 1.000 24.66852  ? 48  ALA A HA   1 
ATOM   714  H  HB1  . ALA A 1 68  ? 4.95361   2.16722   -30.04017 1.000 25.17346  ? 48  ALA A HB1  1 
ATOM   715  H  HB2  . ALA A 1 68  ? 3.67701   1.75739   -30.89213 1.000 25.17346  ? 48  ALA A HB2  1 
ATOM   716  H  HB3  . ALA A 1 68  ? 4.21468   0.79086   -29.75185 1.000 25.17346  ? 48  ALA A HB3  1 
ATOM   717  N  N    . VAL A 1 69  ? 6.74903   -0.76880  -30.10035 1.000 19.79668  ? 49  VAL A N    1 
ATOM   718  C  CA   . VAL A 1 69  ? 8.02007   -1.16695  -29.48231 1.000 19.04394  ? 49  VAL A CA   1 
ATOM   719  C  C    . VAL A 1 69  ? 9.07472   -1.40530  -30.56276 1.000 21.39035  ? 49  VAL A C    1 
ATOM   720  O  O    . VAL A 1 69  ? 10.19952  -0.89385  -30.46249 1.000 21.01820  ? 49  VAL A O    1 
ATOM   721  C  CB   . VAL A 1 69  ? 7.83595   -2.39961  -28.56617 1.000 19.95131  ? 49  VAL A CB   1 
ATOM   722  C  CG1  . VAL A 1 69  ? 9.19457   -2.95392  -28.14191 1.000 21.16158  ? 49  VAL A CG1  1 
ATOM   723  C  CG2  . VAL A 1 69  ? 6.94686   -2.03276  -27.34430 1.000 19.08192  ? 49  VAL A CG2  1 
ATOM   724  H  H    . VAL A 1 69  ? 6.09235   -1.31036  -29.97750 1.000 23.77978  ? 49  VAL A H    1 
ATOM   725  H  HA   . VAL A 1 69  ? 8.32690   -0.44018  -28.91790 1.000 22.87649  ? 49  VAL A HA   1 
ATOM   726  H  HB   . VAL A 1 69  ? 7.37983   -3.10363  -29.05320 1.000 23.96533  ? 49  VAL A HB   1 
ATOM   727  H  HG11 . VAL A 1 69  ? 9.06274   -3.60934  -27.43910 1.000 25.41765  ? 49  VAL A HG11 1 
ATOM   728  H  HG12 . VAL A 1 69  ? 9.61861   -3.37120  -28.90805 1.000 25.41765  ? 49  VAL A HG12 1 
ATOM   729  H  HG13 . VAL A 1 69  ? 9.74505   -2.22502  -27.81543 1.000 25.41765  ? 49  VAL A HG13 1 
ATOM   730  H  HG21 . VAL A 1 69  ? 6.82738   -2.82153  -26.79252 1.000 22.92206  ? 49  VAL A HG21 1 
ATOM   731  H  HG22 . VAL A 1 69  ? 7.38525   -1.33470  -26.83299 1.000 22.92206  ? 49  VAL A HG22 1 
ATOM   732  H  HG23 . VAL A 1 69  ? 6.08627   -1.71853  -27.66295 1.000 22.92206  ? 49  VAL A HG23 1 
ATOM   733  N  N    . ILE A 1 70  ? 8.74358   -2.20418  -31.59079 1.000 20.04632  ? 50  ILE A N    1 
ATOM   734  C  CA   . ILE A 1 70  ? 9.68307   -2.46681  -32.70145 1.000 23.40565  ? 50  ILE A CA   1 
ATOM   735  C  C    . ILE A 1 70  ? 10.13716  -1.17076  -33.36125 1.000 23.28761  ? 50  ILE A C    1 
ATOM   736  O  O    . ILE A 1 70  ? 11.33080  -0.96826  -33.64167 1.000 24.81519  ? 50  ILE A O    1 
ATOM   737  C  CB   . ILE A 1 70  ? 9.06792   -3.41068  -33.75158 1.000 26.97099  ? 50  ILE A CB   1 
ATOM   738  C  CG1  . ILE A 1 70  ? 8.92897   -4.81752  -33.19624 1.000 29.58474  ? 50  ILE A CG1  1 
ATOM   739  C  CG2  . ILE A 1 70  ? 9.90711   -3.40470  -35.03324 1.000 34.55538  ? 50  ILE A CG2  1 
ATOM   740  C  CD1  . ILE A 1 70  ? 10.20509  -5.44149  -32.78210 1.000 37.69812  ? 50  ILE A CD1  1 
ATOM   741  H  H    . ILE A 1 70  ? 7.98701   -2.60504  -31.67148 1.000 24.07934  ? 50  ILE A H    1 
ATOM   742  H  HA   . ILE A 1 70  ? 10.45675  -2.90295  -32.31145 1.000 28.11054  ? 50  ILE A HA   1 
ATOM   743  H  HB   . ILE A 1 70  ? 8.17925   -3.08760  -33.96787 1.000 32.38895  ? 50  ILE A HB   1 
ATOM   744  H  HG12 . ILE A 1 70  ? 8.35146   -4.78685  -32.41750 1.000 35.52545  ? 50  ILE A HG12 1 
ATOM   745  H  HG13 . ILE A 1 70  ? 8.53488   -5.38209  -33.87951 1.000 35.52545  ? 50  ILE A HG13 1 
ATOM   746  H  HG21 . ILE A 1 70  ? 9.71842   -4.21122  -35.53803 1.000 41.49022  ? 50  ILE A HG21 1 
ATOM   747  H  HG22 . ILE A 1 70  ? 9.67489   -2.62340  -35.55912 1.000 41.49022  ? 50  ILE A HG22 1 
ATOM   748  H  HG23 . ILE A 1 70  ? 10.84700  -3.37577  -34.79517 1.000 41.49022  ? 50  ILE A HG23 1 
ATOM   749  H  HD11 . ILE A 1 70  ? 10.07100  -6.39671  -32.67983 1.000 45.26151  ? 50  ILE A HD11 1 
ATOM   750  H  HD12 . ILE A 1 70  ? 10.87487  -5.27253  -33.46309 1.000 45.26151  ? 50  ILE A HD12 1 
ATOM   751  H  HD13 . ILE A 1 70  ? 10.48649  -5.05474  -31.93822 1.000 45.26151  ? 50  ILE A HD13 1 
ATOM   752  N  N    . ASP A 1 71  ? 9.19158   -0.26838  -33.63646 1.000 21.32534  ? 51  ASP A N    1 
ATOM   753  C  CA   . ASP A 1 71  ? 9.54389   0.94815   -34.33754 1.000 24.08797  ? 51  ASP A CA   1 
ATOM   754  C  C    . ASP A 1 71  ? 10.48673  1.80955   -33.50489 1.000 24.50794  ? 51  ASP A C    1 
ATOM   755  O  O    . ASP A 1 71  ? 11.37284  2.46345   -34.06614 1.000 26.07238  ? 51  ASP A O    1 
ATOM   756  C  CB   . ASP A 1 71  ? 8.29109   1.73317   -34.72555 1.000 26.61919  ? 51  ASP A CB   1 
ATOM   757  C  CG   . ASP A 1 71  ? 7.53286   1.11077   -35.88737 1.000 29.22306  ? 51  ASP A CG   1 
ATOM   758  O  OD1  . ASP A 1 71  ? 8.08849   0.21317   -36.57265 1.000 31.32612  ? 51  ASP A OD1  1 
ATOM   759  O  OD2  . ASP A 1 71  ? 6.37201   1.53328   -36.17808 1.000 28.80149  ? 51  ASP A OD2  1 
ATOM   760  H  H    . ASP A 1 71  ? 8.36006   -0.34200  -33.42968 1.000 25.61417  ? 51  ASP A H    1 
ATOM   761  H  HA   . ASP A 1 71  ? 9.99991   0.70760   -35.15917 1.000 28.92932  ? 51  ASP A HA   1 
ATOM   762  H  HB2  . ASP A 1 71  ? 7.69263   1.76787   -33.96296 1.000 31.96680  ? 51  ASP A HB2  1 
ATOM   763  H  HB3  . ASP A 1 71  ? 8.55016   2.63118   -34.98509 1.000 31.96680  ? 51  ASP A HB3  1 
ATOM   764  N  N    . ALA A 1 72  ? 10.30954  1.83514   -32.18294 1.000 22.28224  ? 52  ALA A N    1 
ATOM   765  C  CA   . ALA A 1 72  ? 11.21670  2.58421   -31.33207 1.000 21.96144  ? 52  ALA A CA   1 
ATOM   766  C  C    . ALA A 1 72  ? 12.59251  1.91229   -31.26732 1.000 22.79678  ? 52  ALA A C    1 
ATOM   767  O  O    . ALA A 1 72  ? 13.63050  2.59300   -31.36605 1.000 22.37038  ? 52  ALA A O    1 
ATOM   768  C  CB   . ALA A 1 72  ? 10.60705  2.73115   -29.91644 1.000 22.40257  ? 52  ALA A CB   1 
ATOM   769  H  H    . ALA A 1 72  ? 9.67758   1.43028   -31.76303 1.000 26.76245  ? 52  ALA A H    1 
ATOM   770  H  HA   . ALA A 1 72  ? 11.33701  3.47388   -31.69935 1.000 26.37749  ? 52  ALA A HA   1 
ATOM   771  H  HB1  . ALA A 1 72  ? 11.23306  3.21019   -29.35117 1.000 26.90685  ? 52  ALA A HB1  1 
ATOM   772  H  HB2  . ALA A 1 72  ? 9.77468   3.22504   -29.98078 1.000 26.90685  ? 52  ALA A HB2  1 
ATOM   773  H  HB3  . ALA A 1 72  ? 10.44036  1.84815   -29.55117 1.000 26.90685  ? 52  ALA A HB3  1 
ATOM   774  N  N    . GLU A 1 73  ? 12.60456  0.58233   -31.13745 1.000 23.71594  ? 53  GLU A N    1 
ATOM   775  C  CA   . GLU A 1 73  ? 13.85848  -0.17714  -31.11038 1.000 23.46699  ? 53  GLU A CA   1 
ATOM   776  C  C    . GLU A 1 73  ? 14.67570  0.03585   -32.38541 1.000 24.40199  ? 53  GLU A C    1 
ATOM   777  O  O    . GLU A 1 73  ? 15.91503  0.10018   -32.33031 1.000 27.52304  ? 53  GLU A O    1 
ATOM   778  C  CB   . GLU A 1 73  ? 13.57865  -1.67443  -30.94683 1.000 22.83256  ? 53  GLU A CB   1 
ATOM   779  C  CG   . GLU A 1 73  ? 12.99122  -2.09837  -29.61624 1.000 23.06809  ? 53  GLU A CG   1 
ATOM   780  C  CD   . GLU A 1 73  ? 14.04252  -2.28759  -28.54596 1.000 23.59778  ? 53  GLU A CD   1 
ATOM   781  O  OE1  . GLU A 1 73  ? 15.03163  -1.50515  -28.58350 1.000 24.20501  ? 53  GLU A OE1  1 
ATOM   782  O  OE2  . GLU A 1 73  ? 13.85654  -3.20171  -27.70240 1.000 22.63739  ? 53  GLU A OE2  1 
ATOM   783  H  H    . GLU A 1 73  ? 11.90041  0.09423   -31.06304 1.000 28.48289  ? 53  GLU A H    1 
ATOM   784  H  HA   . GLU A 1 73  ? 14.37181  0.13402   -30.34843 1.000 28.18415  ? 53  GLU A HA   1 
ATOM   785  H  HB2  . GLU A 1 73  ? 12.95066  -1.94247  -31.63580 1.000 27.42283  ? 53  GLU A HB2  1 
ATOM   786  H  HB3  . GLU A 1 73  ? 14.41532  -2.15289  -31.05622 1.000 27.42283  ? 53  GLU A HB3  1 
ATOM   787  H  HG2  . GLU A 1 73  ? 12.37291  -1.41576  -29.31188 1.000 27.70547  ? 53  GLU A HG2  1 
ATOM   788  H  HG3  . GLU A 1 73  ? 12.52486  -2.94116  -29.73081 1.000 27.70547  ? 53  GLU A HG3  1 
ATOM   789  N  N    . ARG A 1 74  ? 13.99853  0.17934   -33.53927 1.000 23.09317  ? 54  ARG A N    1 
ATOM   790  C  CA   . ARG A 1 74  ? 14.66581  0.35085   -34.82948 1.000 25.19418  ? 54  ARG A CA   1 
ATOM   791  C  C    . ARG A 1 74  ? 15.18269  1.76766   -35.05967 1.000 27.57999  ? 54  ARG A C    1 
ATOM   792  O  O    . ARG A 1 74  ? 15.85949  2.02316   -36.06590 1.000 30.56785  ? 54  ARG A O    1 
ATOM   793  C  CB   . ARG A 1 74  ? 13.73125  -0.05313  -35.97620 1.000 29.24141  ? 54  ARG A CB   1 
ATOM   794  C  CG   . ARG A 1 74  ? 13.60566  -1.53270  -36.11568 1.000 37.40152  ? 54  ARG A CG   1 
ATOM   795  C  CD   . ARG A 1 74  ? 12.49204  -1.91527  -37.07362 1.000 44.04715  ? 54  ARG A CD   1 
ATOM   796  N  NE   . ARG A 1 74  ? 12.73231  -3.23395  -37.64424 1.000 65.24598  ? 54  ARG A NE   1 
ATOM   797  C  CZ   . ARG A 1 74  ? 11.84374  -3.90916  -38.35782 1.000 63.81610  ? 54  ARG A CZ   1 
ATOM   798  N  NH1  . ARG A 1 74  ? 10.63998  -3.41866  -38.59727 1.000 58.94822  ? 54  ARG A NH1  1 
ATOM   799  N  NH2  . ARG A 1 74  ? 12.16605  -5.11430  -38.82329 1.000 64.30927  ? 54  ARG A NH2  1 
ATOM   800  H  H    . ARG A 1 74  ? 13.14033  0.17986   -33.59498 1.000 27.73557  ? 54  ARG A H    1 
ATOM   801  H  HA   . ARG A 1 74  ? 15.43054  -0.24548  -34.85152 1.000 30.25678  ? 54  ARG A HA   1 
ATOM   802  H  HB2  . ARG A 1 74  ? 12.84771  0.30988   -35.80748 1.000 35.11345  ? 54  ARG A HB2  1 
ATOM   803  H  HB3  . ARG A 1 74  ? 14.08132  0.29960   -36.80923 1.000 35.11345  ? 54  ARG A HB3  1 
ATOM   804  H  HG2  . ARG A 1 74  ? 14.43825  -1.89396  -36.45803 1.000 44.90558  ? 54  ARG A HG2  1 
ATOM   805  H  HG3  . ARG A 1 74  ? 13.40730  -1.92043  -35.24895 1.000 44.90558  ? 54  ARG A HG3  1 
ATOM   806  H  HD2  . ARG A 1 74  ? 11.64736  -1.93487  -36.59715 1.000 52.88034  ? 54  ARG A HD2  1 
ATOM   807  H  HD3  . ARG A 1 74  ? 12.45037  -1.26964  -37.79634 1.000 52.88034  ? 54  ARG A HD3  1 
ATOM   808  H  HE   . ARG A 1 74  ? 13.50003  -3.59723  -37.50920 1.000 78.31894  ? 54  ARG A HE   1 
ATOM   809  H  HH11 . ARG A 1 74  ? 10.42074  -2.64686  -38.28767 1.000 70.76162  ? 54  ARG A HH11 1 
ATOM   810  H  HH12 . ARG A 1 74  ? 10.07597  -3.87132  -39.06267 1.000 70.76162  ? 54  ARG A HH12 1 
ATOM   811  H  HH21 . ARG A 1 74  ? 12.94287  -5.44492  -38.65944 1.000 77.19489  ? 54  ARG A HH21 1 
ATOM   812  H  HH22 . ARG A 1 74  ? 11.59740  -5.56207  -39.28777 1.000 77.19489  ? 54  ARG A HH22 1 
ATOM   813  N  N    . GLN A 1 75  ? 14.90888  2.68894   -34.14456 1.000 26.45682  ? 55  GLN A N    1 
ATOM   814  C  CA   . GLN A 1 75  ? 15.29592  4.08686   -34.27537 1.000 26.36223  ? 55  GLN A CA   1 
ATOM   815  C  C    . GLN A 1 75  ? 16.11405  4.53026   -33.07035 1.000 27.22382  ? 55  GLN A C    1 
ATOM   816  O  O    . GLN A 1 75  ? 15.71105  5.44154   -32.34046 1.000 25.02587  ? 55  GLN A O    1 
ATOM   817  C  CB   . GLN A 1 75  ? 14.06624  4.97363   -34.45727 1.000 27.94771  ? 55  GLN A CB   1 
ATOM   818  C  CG   . GLN A 1 75  ? 13.28489  4.68170   -35.74671 1.000 29.28708  ? 55  GLN A CG   1 
ATOM   819  C  CD   . GLN A 1 75  ? 12.07185  5.57177   -35.84164 1.000 34.75159  ? 55  GLN A CD   1 
ATOM   820  O  OE1  . GLN A 1 75  ? 10.96546  5.17023   -35.51065 1.000 36.21914  ? 55  GLN A OE1  1 
ATOM   821  N  NE2  . GLN A 1 75  ? 12.27716  6.77470   -36.31495 1.000 33.43297  ? 55  GLN A NE2  1 
ATOM   822  H  H    . GLN A 1 75  ? 14.48550  2.52195   -33.41486 1.000 31.77195  ? 55  GLN A H    1 
ATOM   823  H  HA   . GLN A 1 75  ? 15.85768  4.18118   -35.06050 1.000 31.65844  ? 55  GLN A HA   1 
ATOM   824  H  HB2  . GLN A 1 75  ? 13.46618  4.83353   -33.70814 1.000 33.56101  ? 55  GLN A HB2  1 
ATOM   825  H  HB3  . GLN A 1 75  ? 14.35067  5.90055   -34.48568 1.000 33.56101  ? 55  GLN A HB3  1 
ATOM   826  H  HG2  . GLN A 1 75  ? 13.85246  4.84906   -36.51531 1.000 35.16825  ? 55  GLN A HG2  1 
ATOM   827  H  HG3  . GLN A 1 75  ? 12.99116  3.75725   -35.74621 1.000 35.16825  ? 55  GLN A HG3  1 
ATOM   828  H  HE21 . GLN A 1 75  ? 13.06877  7.01503   -36.54989 1.000 40.14333  ? 55  GLN A HE21 1 
ATOM   829  H  HE22 . GLN A 1 75  ? 11.62045  7.32475   -36.39100 1.000 40.14333  ? 55  GLN A HE22 1 
ATOM   830  N  N    . PRO A 1 76  ? 17.29151  3.93015   -32.84820 1.000 28.01789  ? 56  PRO A N    1 
ATOM   831  C  CA   . PRO A 1 76  ? 18.05937  4.29235   -31.65265 1.000 27.80069  ? 56  PRO A CA   1 
ATOM   832  C  C    . PRO A 1 76  ? 18.55624  5.73004   -31.64098 1.000 28.44115  ? 56  PRO A C    1 
ATOM   833  O  O    . PRO A 1 76  ? 18.85193  6.23551   -30.53745 1.000 30.48614  ? 56  PRO A O    1 
ATOM   834  C  CB   . PRO A 1 76  ? 19.24146  3.30101   -31.66200 1.000 30.28738  ? 56  PRO A CB   1 
ATOM   835  C  CG   . PRO A 1 76  ? 19.37054  2.90051   -33.12234 1.000 30.89296  ? 56  PRO A CG   1 
ATOM   836  C  CD   . PRO A 1 76  ? 17.96146  2.89165   -33.65876 1.000 28.71633  ? 56  PRO A CD   1 
ATOM   837  H  HA   . PRO A 1 76  ? 17.51490  4.13714   -30.86502 1.000 33.38459  ? 56  PRO A HA   1 
ATOM   838  H  HB2  . PRO A 1 76  ? 20.04732  3.73825   -31.34527 1.000 36.36862  ? 56  PRO A HB2  1 
ATOM   839  H  HB3  . PRO A 1 76  ? 19.03912  2.53377   -31.10406 1.000 36.36862  ? 56  PRO A HB3  1 
ATOM   840  H  HG2  . PRO A 1 76  ? 19.91600  3.54880   -33.59468 1.000 37.09532  ? 56  PRO A HG2  1 
ATOM   841  H  HG3  . PRO A 1 76  ? 19.77083  2.01941   -33.18808 1.000 37.09532  ? 56  PRO A HG3  1 
ATOM   842  H  HD2  . PRO A 1 76  ? 17.94769  3.12454   -34.60029 1.000 34.48335  ? 56  PRO A HD2  1 
ATOM   843  H  HD3  . PRO A 1 76  ? 17.54528  2.02573   -33.52508 1.000 34.48335  ? 56  PRO A HD3  1 
ATOM   844  N  N    . GLU A 1 77  ? 18.69559  6.38649   -32.80884 1.000 30.70962  ? 57  GLU A N    1 
ATOM   845  C  CA   . GLU A 1 77  ? 19.12912  7.77717   -32.81992 1.000 32.40821  ? 57  GLU A CA   1 
ATOM   846  C  C    . GLU A 1 77  ? 18.06306  8.70039   -32.25311 1.000 35.52600  ? 57  GLU A C    1 
ATOM   847  O  O    . GLU A 1 77  ? 18.39367  9.77805   -31.74852 1.000 36.37176  ? 57  GLU A O    1 
ATOM   848  C  CB   . GLU A 1 77  ? 19.54445  8.19932   -34.24601 1.000 35.23683  ? 57  GLU A CB   1 
ATOM   849  C  CG   . GLU A 1 77  ? 20.69982  7.33436   -34.75836 1.000 43.09848  ? 57  GLU A CG   1 
ATOM   850  C  CD   . GLU A 1 77  ? 21.20735  7.72527   -36.13391 1.000 55.74063  ? 57  GLU A CD   1 
ATOM   851  O  OE1  . GLU A 1 77  ? 20.79827  8.79043   -36.65899 1.000 49.54168  ? 57  GLU A OE1  1 
ATOM   852  O  OE2  . GLU A 1 77  ? 22.05030  6.96454   -36.66170 1.000 48.99920  ? 57  GLU A OE2  1 
ATOM   853  H  H    . GLU A 1 77  ? 18.54650  6.04866   -33.58553 1.000 36.87530  ? 57  GLU A H    1 
ATOM   854  H  HA   . GLU A 1 77  ? 19.91950  7.87482   -32.26615 1.000 38.91361  ? 57  GLU A HA   1 
ATOM   855  H  HB2  . GLU A 1 77  ? 18.79016  8.09286   -34.84652 1.000 42.30796  ? 57  GLU A HB2  1 
ATOM   856  H  HB3  . GLU A 1 77  ? 19.83331  9.12527   -34.23711 1.000 42.30796  ? 57  GLU A HB3  1 
ATOM   857  H  HG2  . GLU A 1 77  ? 21.44246  7.40967   -34.13892 1.000 51.74193  ? 57  GLU A HG2  1 
ATOM   858  H  HG3  . GLU A 1 77  ? 20.40023  6.41305   -34.80669 1.000 51.74193  ? 57  GLU A HG3  1 
ATOM   859  N  N    . LEU A 1 78  ? 16.80492  8.29828   -32.30495 1.000 29.81878  ? 58  LEU A N    1 
ATOM   860  C  CA   . LEU A 1 78  ? 15.69220  9.06703   -31.73907 1.000 28.64350  ? 58  LEU A CA   1 
ATOM   861  C  C    . LEU A 1 78  ? 15.30752  8.59571   -30.34640 1.000 26.39730  ? 58  LEU A C    1 
ATOM   862  O  O    . LEU A 1 78  ? 15.02332  9.42168   -29.46430 1.000 25.86349  ? 58  LEU A O    1 
ATOM   863  C  CB   . LEU A 1 78  ? 14.48959  8.95522   -32.67299 1.000 30.14306  ? 58  LEU A CB   1 
ATOM   864  C  CG   . LEU A 1 78  ? 13.21923  9.68905   -32.27594 1.000 32.28580  ? 58  LEU A CG   1 
ATOM   865  C  CD1  . LEU A 1 78  ? 13.49714  11.16833  -32.06261 1.000 34.03070  ? 58  LEU A CD1  1 
ATOM   866  C  CD2  . LEU A 1 78  ? 12.15132  9.49259   -33.38579 1.000 32.54403  ? 58  LEU A CD2  1 
ATOM   867  H  H    . LEU A 1 78  ? 16.55516  7.56194   -32.67242 1.000 35.80630  ? 58  LEU A H    1 
ATOM   868  H  HA   . LEU A 1 78  ? 15.93793  10.00277  -31.66907 1.000 34.39596  ? 58  LEU A HA   1 
ATOM   869  H  HB2  . LEU A 1 78  ? 14.75431  9.30179   -33.53943 1.000 36.19543  ? 58  LEU A HB2  1 
ATOM   870  H  HB3  . LEU A 1 78  ? 14.25902  8.01599   -32.74770 1.000 36.19543  ? 58  LEU A HB3  1 
ATOM   871  H  HG   . LEU A 1 78  ? 12.88090  9.33136   -31.44019 1.000 38.76672  ? 58  LEU A HG   1 
ATOM   872  H  HD11 . LEU A 1 78  ? 12.66079  11.62321  -31.87688 1.000 40.86060  ? 58  LEU A HD11 1 
ATOM   873  H  HD12 . LEU A 1 78  ? 14.10316  11.27079  -31.31218 1.000 40.86060  ? 58  LEU A HD12 1 
ATOM   874  H  HD13 . LEU A 1 78  ? 13.90068  11.53288  -32.86583 1.000 40.86060  ? 58  LEU A HD13 1 
ATOM   875  H  HD21 . LEU A 1 78  ? 11.35984  10.00438  -33.15662 1.000 39.07659  ? 58  LEU A HD21 1 
ATOM   876  H  HD22 . LEU A 1 78  ? 12.51296  9.80322   -34.23055 1.000 39.07659  ? 58  LEU A HD22 1 
ATOM   877  H  HD23 . LEU A 1 78  ? 11.92956  8.55029   -33.44741 1.000 39.07659  ? 58  LEU A HD23 1 
ATOM   878  N  N    . PHE A 1 79  ? 15.35552  7.29116   -30.12585 1.000 24.96540  ? 59  PHE A N    1 
ATOM   879  C  CA   . PHE A 1 79  ? 15.03095  6.64400   -28.85838 1.000 23.96653  ? 59  PHE A CA   1 
ATOM   880  C  C    . PHE A 1 79  ? 16.32412  6.05860   -28.29314 1.000 22.52507  ? 59  PHE A C    1 
ATOM   881  O  O    . PHE A 1 79  ? 16.68326  4.91093   -28.58743 1.000 23.48777  ? 59  PHE A O    1 
ATOM   882  C  CB   . PHE A 1 79  ? 13.99371  5.56112   -29.09055 1.000 23.09945  ? 59  PHE A CB   1 
ATOM   883  C  CG   . PHE A 1 79  ? 12.64563  6.07836   -29.55125 1.000 24.30973  ? 59  PHE A CG   1 
ATOM   884  C  CD1  . PHE A 1 79  ? 11.71082  6.51089   -28.62266 1.000 25.76564  ? 59  PHE A CD1  1 
ATOM   885  C  CD2  . PHE A 1 79  ? 12.30749  6.10178   -30.89685 1.000 25.00773  ? 59  PHE A CD2  1 
ATOM   886  C  CE1  . PHE A 1 79  ? 10.46714  7.00052   -29.05298 1.000 23.50247  ? 59  PHE A CE1  1 
ATOM   887  C  CE2  . PHE A 1 79  ? 11.05231  6.57625   -31.31966 1.000 25.40929  ? 59  PHE A CE2  1 
ATOM   888  C  CZ   . PHE A 1 79  ? 10.13121  6.99909   -30.37670 1.000 24.42636  ? 59  PHE A CZ   1 
ATOM   889  H  H    . PHE A 1 79  ? 15.58687  6.72419   -30.72968 1.000 29.98225  ? 59  PHE A H    1 
ATOM   890  H  HA   . PHE A 1 79  ? 14.68664  7.29547   -28.22756 1.000 28.78360  ? 59  PHE A HA   1 
ATOM   891  H  HB2  . PHE A 1 79  ? 14.32488  4.95584   -29.77236 1.000 27.74310  ? 59  PHE A HB2  1 
ATOM   892  H  HB3  . PHE A 1 79  ? 13.85571  5.08081   -28.25919 1.000 27.74310  ? 59  PHE A HB3  1 
ATOM   893  H  HD1  . PHE A 1 79  ? 11.90776  6.47663   -27.71440 1.000 30.94253  ? 59  PHE A HD1  1 
ATOM   894  H  HD2  . PHE A 1 79  ? 12.91952  5.79941   -31.52843 1.000 30.03304  ? 59  PHE A HD2  1 
ATOM   895  H  HE1  . PHE A 1 79  ? 9.86334   7.33062   -28.42739 1.000 28.22673  ? 59  PHE A HE1  1 
ATOM   896  H  HE2  . PHE A 1 79  ? 10.84309  6.60558   -32.22535 1.000 30.51491  ? 59  PHE A HE2  1 
ATOM   897  H  HZ   . PHE A 1 79  ? 9.28628   7.28131   -30.64381 1.000 29.33539  ? 59  PHE A HZ   1 
ATOM   898  N  N    . SER A 1 80  ? 17.01141  6.85688   -27.47126 1.000 23.84865  ? 60  SER A N    1 
ATOM   899  C  CA   . SER A 1 80  ? 18.36422  6.56932   -27.02023 1.000 24.90318  ? 60  SER A CA   1 
ATOM   900  C  C    . SER A 1 80  ? 18.39413  5.79566   -25.70312 1.000 23.95258  ? 60  SER A C    1 
ATOM   901  O  O    . SER A 1 80  ? 17.50182  5.90019   -24.85675 1.000 23.70564  ? 60  SER A O    1 
ATOM   902  C  CB   . SER A 1 80  ? 19.10281  7.89663   -26.89507 1.000 26.64314  ? 60  SER A CB   1 
ATOM   903  O  OG   . SER A 1 80  ? 20.34671  7.81028   -26.21236 1.000 26.54930  ? 60  SER A OG   1 
ATOM   904  H  H    . SER A 1 80  ? 16.70104  7.59344   -27.15386 1.000 28.64215  ? 60  SER A H    1 
ATOM   905  H  HA   . SER A 1 80  ? 18.81680  5.99364   -27.65637 1.000 29.90758  ? 60  SER A HA   1 
ATOM   906  H  HB2  . SER A 1 80  ? 19.27156  8.23383   -27.78878 1.000 31.99553  ? 60  SER A HB2  1 
ATOM   907  H  HB3  . SER A 1 80  ? 18.53394  8.51420   -26.40939 1.000 31.99553  ? 60  SER A HB3  1 
ATOM   908  H  HG   . SER A 1 80  ? 20.77831  7.14316   -26.48488 1.000 31.88292  ? 60  SER A HG   1 
ATOM   909  N  N    . ASN A 1 81  ? 19.47213  5.05267   -25.50828 1.000 23.80527  ? 61  ASN A N    1 
ATOM   910  C  CA   . ASN A 1 81  ? 19.73845  4.38175   -24.23681 1.000 24.19411  ? 61  ASN A CA   1 
ATOM   911  C  C    . ASN A 1 81  ? 20.65768  5.19883   -23.34285 1.000 26.11322  ? 61  ASN A C    1 
ATOM   912  O  O    . ASN A 1 81  ? 20.90549  4.80116   -22.20108 1.000 25.21729  ? 61  ASN A O    1 
ATOM   913  C  CB   . ASN A 1 81  ? 20.37990  3.00737   -24.48773 1.000 24.03994  ? 61  ASN A CB   1 
ATOM   914  C  CG   . ASN A 1 81  ? 19.34773  1.92612   -24.81131 1.000 23.50676  ? 61  ASN A CG   1 
ATOM   915  O  OD1  . ASN A 1 81  ? 18.49603  2.08140   -25.67624 1.000 23.92519  ? 61  ASN A OD1  1 
ATOM   916  N  ND2  . ASN A 1 81  ? 19.45602  0.80770   -24.12180 1.000 23.14769  ? 61  ASN A ND2  1 
ATOM   917  H  H    . ASN A 1 81  ? 20.07697  4.91682   -26.10436 1.000 28.59009  ? 61  ASN A H    1 
ATOM   918  H  HA   . ASN A 1 81  ? 18.90015  4.23601   -23.77109 1.000 29.05669  ? 61  ASN A HA   1 
ATOM   919  H  HB2  . ASN A 1 81  ? 20.98968  3.07506   -25.23905 1.000 28.87169  ? 61  ASN A HB2  1 
ATOM   920  H  HB3  . ASN A 1 81  ? 20.86268  2.73340   -23.69226 1.000 28.87169  ? 61  ASN A HB3  1 
ATOM   921  H  HD21 . ASN A 1 81  ? 18.90409  0.16266   -24.25924 1.000 27.80099  ? 61  ASN A HD21 1 
ATOM   922  H  HD22 . ASN A 1 81  ? 20.07860  0.72316   -23.53455 1.000 27.80099  ? 61  ASN A HD22 1 
ATOM   923  N  N    . ALA A 1 82  ? 21.18895  6.30915   -23.85043 1.000 24.93232  ? 62  ALA A N    1 
ATOM   924  C  CA   . ALA A 1 82  ? 22.24955  7.01268   -23.13853 1.000 27.72323  ? 62  ALA A CA   1 
ATOM   925  C  C    . ALA A 1 82  ? 21.75494  7.84842   -21.96065 1.000 27.22087  ? 62  ALA A C    1 
ATOM   926  O  O    . ALA A 1 82  ? 22.59903  8.38957   -21.21531 1.000 29.57112  ? 62  ALA A O    1 
ATOM   927  C  CB   . ALA A 1 82  ? 23.02715  7.89318   -24.12196 1.000 28.83512  ? 62  ALA A CB   1 
ATOM   928  H  H    . ALA A 1 82  ? 20.95447  6.66902   -24.59549 1.000 29.94254  ? 62  ALA A H    1 
ATOM   929  H  HA   . ALA A 1 82  ? 22.86071  6.35521   -22.77094 1.000 33.29163  ? 62  ALA A HA   1 
ATOM   930  H  HB1  . ALA A 1 82  ? 23.73279  8.35489   -23.64260 1.000 34.62591  ? 62  ALA A HB1  1 
ATOM   931  H  HB2  . ALA A 1 82  ? 23.41004  7.33158   -24.81400 1.000 34.62591  ? 62  ALA A HB2  1 
ATOM   932  H  HB3  . ALA A 1 82  ? 22.41950  8.53757   -24.51746 1.000 34.62591  ? 62  ALA A HB3  1 
ATOM   933  N  N    . GLY A 1 83  ? 20.44672  7.94411   -21.74125 1.000 27.09817  ? 63  GLY A N    1 
ATOM   934  C  CA   . GLY A 1 83  ? 19.92338  8.52241   -20.52405 1.000 27.30730  ? 63  GLY A CA   1 
ATOM   935  C  C    . GLY A 1 83  ? 19.68270  7.52207   -19.40495 1.000 28.59554  ? 63  GLY A C    1 
ATOM   936  O  O    . GLY A 1 83  ? 19.24949  7.91484   -18.30982 1.000 29.20855  ? 63  GLY A O    1 
ATOM   937  H  H    . GLY A 1 83  ? 19.84258  7.67662   -22.29177 1.000 32.54157  ? 63  GLY A H    1 
ATOM   938  H  HA2  . GLY A 1 83  ? 20.55086  9.18706   -20.19939 1.000 32.79252  ? 63  GLY A HA2  1 
ATOM   939  H  HA3  . GLY A 1 83  ? 19.07868  8.95597   -20.72258 1.000 32.79252  ? 63  GLY A HA3  1 
ATOM   940  N  N    . GLY A 1 84  ? 20.00701  6.25446   -19.64180 1.000 26.26698  ? 64  GLY A N    1 
ATOM   941  C  CA   . GLY A 1 84  ? 19.68856  5.17414   -18.71658 1.000 24.86037  ? 64  GLY A CA   1 
ATOM   942  C  C    . GLY A 1 84  ? 18.36791  4.50095   -19.04091 1.000 23.78577  ? 64  GLY A C    1 
ATOM   943  O  O    . GLY A 1 84  ? 17.45637  5.10104   -19.61816 1.000 24.13195  ? 64  GLY A O    1 
ATOM   944  H  H    . GLY A 1 84  ? 20.42103  5.98776   -20.34682 1.000 31.54413  ? 64  GLY A H    1 
ATOM   945  H  HA2  . GLY A 1 84  ? 20.38928  4.50437   -18.75258 1.000 29.85621  ? 64  GLY A HA2  1 
ATOM   946  H  HA3  . GLY A 1 84  ? 19.63682  5.52892   -17.81527 1.000 29.85621  ? 64  GLY A HA3  1 
ATOM   947  N  N    . ILE A 1 85  ? 18.25085  3.23412   -18.63444 1.000 22.12130  ? 65  ILE A N    1 
ATOM   948  C  CA   . ILE A 1 85  ? 17.09658  2.42625   -19.04109 1.000 19.61485  ? 65  ILE A CA   1 
ATOM   949  C  C    . ILE A 1 85  ? 16.01561  2.32955   -17.94984 1.000 22.14674  ? 65  ILE A C    1 
ATOM   950  O  O    . ILE A 1 85  ? 15.03096  1.59236   -18.13736 1.000 20.67540  ? 65  ILE A O    1 
ATOM   951  C  CB   . ILE A 1 85  ? 17.49480  1.03084   -19.56264 1.000 20.23003  ? 65  ILE A CB   1 
ATOM   952  C  CG1  . ILE A 1 85  ? 18.46399  0.27107   -18.65028 1.000 22.07442  ? 65  ILE A CG1  1 
ATOM   953  C  CG2  . ILE A 1 85  ? 18.14383  1.16522   -20.96388 1.000 22.49842  ? 65  ILE A CG2  1 
ATOM   954  C  CD1  . ILE A 1 85  ? 17.88505  -0.16996  -17.37349 1.000 23.46097  ? 65  ILE A CD1  1 
ATOM   955  H  H    . ILE A 1 85  ? 18.81700  2.82673   -18.13134 1.000 26.56932  ? 65  ILE A H    1 
ATOM   956  H  HA   . ILE A 1 85  ? 16.69296  2.89468   -19.78846 1.000 23.56158  ? 65  ILE A HA   1 
ATOM   957  H  HB   . ILE A 1 85  ? 16.67148  0.51877   -19.59131 1.000 24.29980  ? 65  ILE A HB   1 
ATOM   958  H  HG12 . ILE A 1 85  ? 18.77367  -0.51947  -19.11937 1.000 26.51306  ? 65  ILE A HG12 1 
ATOM   959  H  HG13 . ILE A 1 85  ? 19.21430  0.85097   -18.44620 1.000 26.51306  ? 65  ILE A HG13 1 
ATOM   960  H  HG21 . ILE A 1 85  ? 18.40526  0.28500   -21.27655 1.000 27.02186  ? 65  ILE A HG21 1 
ATOM   961  H  HG22 . ILE A 1 85  ? 17.49889  1.55511   -21.57457 1.000 27.02186  ? 65  ILE A HG22 1 
ATOM   962  H  HG23 . ILE A 1 85  ? 18.92402  1.73769   -20.89696 1.000 27.02186  ? 65  ILE A HG23 1 
ATOM   963  H  HD11 . ILE A 1 85  ? 18.45911  -0.84784  -16.98384 1.000 28.17693  ? 65  ILE A HD11 1 
ATOM   964  H  HD12 . ILE A 1 85  ? 17.82018  0.59168   -16.77632 1.000 28.17693  ? 65  ILE A HD12 1 
ATOM   965  H  HD13 . ILE A 1 85  ? 17.00265  -0.53800  -17.53722 1.000 28.17693  ? 65  ILE A HD13 1 
ATOM   966  N  N    . ARG A 1 86  ? 16.10602  3.12282   -16.87557 1.000 21.80946  ? 66  ARG A N    1 
ATOM   967  C  CA   . ARG A 1 86  ? 15.03742  3.24921   -15.86473 1.000 22.07151  ? 66  ARG A CA   1 
ATOM   968  C  C    . ARG A 1 86  ? 14.38618  4.63642   -15.89259 1.000 26.21008  ? 66  ARG A C    1 
ATOM   969  O  O    . ARG A 1 86  ? 14.99837  5.60979   -16.33722 1.000 28.52714  ? 66  ARG A O    1 
ATOM   970  C  CB   . ARG A 1 86  ? 15.57304  2.97569   -14.45761 1.000 22.20104  ? 66  ARG A CB   1 
ATOM   971  C  CG   . ARG A 1 86  ? 16.17553  1.58510   -14.23849 1.000 22.88069  ? 66  ARG A CG   1 
ATOM   972  C  CD   . ARG A 1 86  ? 15.36800  0.45044   -14.85473 1.000 22.24129  ? 66  ARG A CD   1 
ATOM   973  N  NE   . ARG A 1 86  ? 13.98631  0.44363   -14.38322 1.000 20.17743  ? 66  ARG A NE   1 
ATOM   974  C  CZ   . ARG A 1 86  ? 12.93449  0.25301   -15.17477 1.000 22.34854  ? 66  ARG A CZ   1 
ATOM   975  N  NH1  . ARG A 1 86  ? 13.05400  0.19154   -16.48501 1.000 20.56149  ? 66  ARG A NH1  1 
ATOM   976  N  NH2  . ARG A 1 86  ? 11.72752  0.10230   -14.63426 1.000 21.65225  ? 66  ARG A NH2  1 
ATOM   977  H  H    . ARG A 1 86  ? 16.79259  3.61124   -16.70335 1.000 26.19512  ? 66  ARG A H    1 
ATOM   978  H  HA   . ARG A 1 86  ? 14.35253  2.59190   -16.06414 1.000 26.50958  ? 66  ARG A HA   1 
ATOM   979  H  HB2  . ARG A 1 86  ? 16.26766  3.62462   -14.26447 1.000 26.66501  ? 66  ARG A HB2  1 
ATOM   980  H  HB3  . ARG A 1 86  ? 14.84159  3.07546   -13.82839 1.000 26.66501  ? 66  ARG A HB3  1 
ATOM   981  H  HG2  . ARG A 1 86  ? 17.06075  1.56387   -14.63452 1.000 27.48059  ? 66  ARG A HG2  1 
ATOM   982  H  HG3  . ARG A 1 86  ? 16.23471  1.41867   -13.28471 1.000 27.48059  ? 66  ARG A HG3  1 
ATOM   983  H  HD2  . ARG A 1 86  ? 15.35844  0.55270   -15.81928 1.000 26.71331  ? 66  ARG A HD2  1 
ATOM   984  H  HD3  . ARG A 1 86  ? 15.77411  -0.39720  -14.61499 1.000 26.71331  ? 66  ARG A HD3  1 
ATOM   985  H  HE   . ARG A 1 86  ? 13.84415  0.57027   -13.54456 1.000 24.23668  ? 66  ARG A HE   1 
ATOM   986  H  HH11 . ARG A 1 86  ? 13.82787  0.27550   -16.85062 1.000 24.69755  ? 66  ARG A HH11 1 
ATOM   987  H  HH12 . ARG A 1 86  ? 12.35816  0.06743   -16.97492 1.000 24.69755  ? 66  ARG A HH12 1 
ATOM   988  H  HH21 . ARG A 1 86  ? 11.63264  0.12856   -13.77992 1.000 26.00647  ? 66  ARG A HH21 1 
ATOM   989  H  HH22 . ARG A 1 86  ? 11.04256  -0.02135  -15.13938 1.000 26.00647  ? 66  ARG A HH22 1 
ATOM   990  N  N    . PRO A 1 87  ? 13.15053  4.77568   -15.39967 1.000 26.02337  ? 67  PRO A N    1 
ATOM   991  C  CA   . PRO A 1 87  ? 12.42878  6.03499   -15.63852 1.000 30.77937  ? 67  PRO A CA   1 
ATOM   992  C  C    . PRO A 1 87  ? 12.95477  7.20508   -14.83400 1.000 36.55727  ? 67  PRO A C    1 
ATOM   993  O  O    . PRO A 1 87  ? 12.82700  8.35104   -15.28154 1.000 39.08294  ? 67  PRO A O    1 
ATOM   994  C  CB   . PRO A 1 87  ? 10.97526  5.68960   -15.26921 1.000 33.69374  ? 67  PRO A CB   1 
ATOM   995  C  CG   . PRO A 1 87  ? 11.07106  4.45647   -14.38589 1.000 28.95358  ? 67  PRO A CG   1 
ATOM   996  C  CD   . PRO A 1 87  ? 12.26866  3.70166   -14.88433 1.000 25.43727  ? 67  PRO A CD   1 
ATOM   997  H  HA   . PRO A 1 87  ? 12.47176  6.26114   -16.58081 1.000 36.95900  ? 67  PRO A HA   1 
ATOM   998  H  HB2  . PRO A 1 87  ? 10.57282  6.42973   -14.78843 1.000 40.45625  ? 67  PRO A HB2  1 
ATOM   999  H  HB3  . PRO A 1 87  ? 10.46700  5.50094   -16.07356 1.000 40.45625  ? 67  PRO A HB3  1 
ATOM   1000 H  HG2  . PRO A 1 87  ? 11.19122  4.72280   -13.46094 1.000 34.76806  ? 67  PRO A HG2  1 
ATOM   1001 H  HG3  . PRO A 1 87  ? 10.26533  3.92391   -14.47579 1.000 34.76806  ? 67  PRO A HG3  1 
ATOM   1002 H  HD2  . PRO A 1 87  ? 12.69834  3.21791   -14.16166 1.000 30.54848  ? 67  PRO A HD2  1 
ATOM   1003 H  HD3  . PRO A 1 87  ? 12.02049  3.08766   -15.59308 1.000 30.54848  ? 67  PRO A HD3  1 
ATOM   1004 N  N    . ASP A 1 88  ? 13.56604  6.95563   -13.68792 1.000 33.30158  ? 68  ASP A N    1 
ATOM   1005 C  CA   . ASP A 1 88  ? 13.86087  8.01090   -12.71665 1.000 41.77740  ? 68  ASP A CA   1 
ATOM   1006 C  C    . ASP A 1 88  ? 15.30890  7.94899   -12.24317 1.000 37.94682  ? 68  ASP A C    1 
ATOM   1007 O  O    . ASP A 1 88  ? 15.61169  8.37042   -11.12167 1.000 40.06451  ? 68  ASP A O    1 
ATOM   1008 C  CB   . ASP A 1 88  ? 12.93133  7.88489   -11.51024 1.000 50.00295  ? 68  ASP A CB   1 
ATOM   1009 C  CG   . ASP A 1 88  ? 12.88166  6.43890   -10.95534 1.000 69.71452  ? 68  ASP A CG   1 
ATOM   1010 O  OD1  . ASP A 1 88  ? 13.41377  5.49035   -11.61980 1.000 51.99719  ? 68  ASP A OD1  1 
ATOM   1011 O  OD2  . ASP A 1 88  ? 12.33901  6.25246   -9.83571  1.000 79.41135  ? 68  ASP A OD2  1 
ATOM   1012 H  H    . ASP A 1 88  ? 13.82598  6.17389   -13.44108 1.000 39.98566  ? 68  ASP A H    1 
ATOM   1013 H  HA   . ASP A 1 88  ? 13.72273  8.86960   -13.14612 1.000 50.15664  ? 68  ASP A HA   1 
ATOM   1014 H  HB2  . ASP A 1 88  ? 13.24718  8.46898   -10.80315 1.000 60.02730  ? 68  ASP A HB2  1 
ATOM   1015 H  HB3  . ASP A 1 88  ? 12.03277  8.13837   -11.77337 1.000 60.02730  ? 68  ASP A HB3  1 
ATOM   1016 N  N    . GLN A 1 89  ? 16.20891  7.40644   -13.06376 1.000 32.23124  ? 69  GLN A N    1 
ATOM   1017 C  CA   . GLN A 1 89  ? 17.60250  7.19199   -12.68611 1.000 32.86498  ? 69  GLN A CA   1 
ATOM   1018 C  C    . GLN A 1 89  ? 18.50371  7.54925   -13.85671 1.000 30.36376  ? 69  GLN A C    1 
ATOM   1019 O  O    . GLN A 1 89  ? 18.12569  7.34444   -15.01857 1.000 30.06219  ? 69  GLN A O    1 
ATOM   1020 C  CB   . GLN A 1 89  ? 17.83242  5.72464   -12.27748 1.000 35.68610  ? 69  GLN A CB   1 
ATOM   1021 C  CG   . GLN A 1 89  ? 16.93114  5.29697   -11.10800 1.000 38.13508  ? 69  GLN A CG   1 
ATOM   1022 C  CD   . GLN A 1 89  ? 16.96364  3.80874   -10.81333 1.000 39.60459  ? 69  GLN A CD   1 
ATOM   1023 O  OE1  . GLN A 1 89  ? 17.85477  3.09147   -11.25785 1.000 40.12194  ? 69  GLN A OE1  1 
ATOM   1024 N  NE2  . GLN A 1 89  ? 15.95528  3.33313   -10.07685 1.000 41.64581  ? 69  GLN A NE2  1 
ATOM   1025 H  H    . GLN A 1 89  ? 16.02953  7.14860   -13.86435 1.000 38.70125  ? 69  GLN A H    1 
ATOM   1026 H  HA   . GLN A 1 89  ? 17.84274  7.76748   -11.94315 1.000 39.46174  ? 69  GLN A HA   1 
ATOM   1027 H  HB2  . GLN A 1 89  ? 17.63833  5.15014   -13.03457 1.000 42.84708  ? 69  GLN A HB2  1 
ATOM   1028 H  HB3  . GLN A 1 89  ? 18.75626  5.61230   -12.00401 1.000 42.84708  ? 69  GLN A HB3  1 
ATOM   1029 H  HG2  . GLN A 1 89  ? 17.21945  5.76194   -10.30701 1.000 45.78585  ? 69  GLN A HG2  1 
ATOM   1030 H  HG3  . GLN A 1 89  ? 16.01472  5.53539   -11.31830 1.000 45.78585  ? 69  GLN A HG3  1 
ATOM   1031 H  HE21 . GLN A 1 89  ? 15.33766  3.86357   -9.79977  1.000 49.99874  ? 69  GLN A HE21 1 
ATOM   1032 H  HE22 . GLN A 1 89  ? 15.92390  2.49657   -9.87991  1.000 49.99874  ? 69  GLN A HE22 1 
ATOM   1033 N  N    . PRO A 1 90  ? 19.69106  8.08543   -13.57946 1.000 32.30248  ? 70  PRO A N    1 
ATOM   1034 C  CA   . PRO A 1 90  ? 20.62232  8.46768   -14.64746 1.000 32.17218  ? 70  PRO A CA   1 
ATOM   1035 C  C    . PRO A 1 90  ? 21.37178  7.25434   -15.17466 1.000 32.34465  ? 70  PRO A C    1 
ATOM   1036 O  O    . PRO A 1 90  ? 21.32518  6.16770   -14.60963 1.000 32.09459  ? 70  PRO A O    1 
ATOM   1037 C  CB   . PRO A 1 90  ? 21.59091  9.43004   -13.94288 1.000 37.75031  ? 70  PRO A CB   1 
ATOM   1038 C  CG   . PRO A 1 90  ? 21.56971  8.98912   -12.49875 1.000 40.63012  ? 70  PRO A CG   1 
ATOM   1039 C  CD   . PRO A 1 90  ? 20.15949  8.51668   -12.24194 1.000 33.26373  ? 70  PRO A CD   1 
ATOM   1040 H  HA   . PRO A 1 90  ? 20.16066  8.92300   -15.36889 1.000 38.63038  ? 70  PRO A HA   1 
ATOM   1041 H  HB2  . PRO A 1 90  ? 22.47978  9.34443   -14.32166 1.000 45.32413  ? 70  PRO A HB2  1 
ATOM   1042 H  HB3  . PRO A 1 90  ? 21.27793  10.34361  -14.03423 1.000 45.32413  ? 70  PRO A HB3  1 
ATOM   1043 H  HG2  . PRO A 1 90  ? 22.20457  8.26783   -12.36606 1.000 48.77990  ? 70  PRO A HG2  1 
ATOM   1044 H  HG3  . PRO A 1 90  ? 21.79282  9.73750   -11.92338 1.000 48.77990  ? 70  PRO A HG3  1 
ATOM   1045 H  HD2  . PRO A 1 90  ? 20.15322  7.77355   -11.61854 1.000 39.94024  ? 70  PRO A HD2  1 
ATOM   1046 H  HD3  . PRO A 1 90  ? 19.61041  9.24012   -11.90129 1.000 39.94024  ? 70  PRO A HD3  1 
ATOM   1047 N  N    . ALA A 1 91  ? 22.07968  7.47555   -16.27356 1.000 33.16623  ? 71  ALA A N    1 
ATOM   1048 C  CA   . ALA A 1 91  ? 22.84580  6.41741   -16.91326 1.000 30.86302  ? 71  ALA A CA   1 
ATOM   1049 C  C    . ALA A 1 91  ? 23.98747  5.92716   -16.02404 1.000 29.88728  ? 71  ALA A C    1 
ATOM   1050 O  O    . ALA A 1 91  ? 24.62247  6.70989   -15.29327 1.000 34.16856  ? 71  ALA A O    1 
ATOM   1051 C  CB   . ALA A 1 91  ? 23.42241  6.91391   -18.24209 1.000 33.67976  ? 71  ALA A CB   1 
ATOM   1052 H  H    . ALA A 1 91  ? 22.13360  8.23571   -16.67211 1.000 39.82324  ? 71  ALA A H    1 
ATOM   1053 H  HA   . ALA A 1 91  ? 22.25476  5.66676   -17.08088 1.000 37.05939  ? 71  ALA A HA   1 
ATOM   1054 H  HB1  . ALA A 1 91  ? 23.96654  6.21200   -18.63215 1.000 40.43947  ? 71  ALA A HB1  1 
ATOM   1055 H  HB2  . ALA A 1 91  ? 22.69168  7.13672   -18.83983 1.000 40.43947  ? 71  ALA A HB2  1 
ATOM   1056 H  HB3  . ALA A 1 91  ? 23.96576  7.70019   -18.07645 1.000 40.43947  ? 71  ALA A HB3  1 
ATOM   1057 N  N    . LEU A 1 92  ? 24.27385  4.63467   -16.14859 1.000 32.17588  ? 72  LEU A N    1 
ATOM   1058 C  CA   . LEU A 1 92  ? 25.46764  4.00131   -15.59133 1.000 33.43433  ? 72  LEU A CA   1 
ATOM   1059 C  C    . LEU A 1 92  ? 26.45645  3.69337   -16.70211 1.000 36.61621  ? 72  LEU A C    1 
ATOM   1060 O  O    . LEU A 1 92  ? 26.07054  3.53304   -17.86024 1.000 30.52252  ? 72  LEU A O    1 
ATOM   1061 C  CB   . LEU A 1 92  ? 25.10032  2.68729   -14.89377 1.000 36.70463  ? 72  LEU A CB   1 
ATOM   1062 C  CG   . LEU A 1 92  ? 24.10669  2.74142   -13.72315 1.000 38.09438  ? 72  LEU A CG   1 
ATOM   1063 C  CD1  . LEU A 1 92  ? 23.88465  1.37275   -13.15673 1.000 44.50392  ? 72  LEU A CD1  1 
ATOM   1064 C  CD2  . LEU A 1 92  ? 24.66375  3.68693   -12.65419 1.000 48.01842  ? 72  LEU A CD2  1 
ATOM   1065 H  H    . LEU A 1 92  ? 23.77012  4.07942   -16.56995 1.000 38.63482  ? 72  LEU A H    1 
ATOM   1066 H  HA   . LEU A 1 92  ? 25.87977  4.59324   -14.94273 1.000 40.14496  ? 72  LEU A HA   1 
ATOM   1067 H  HB2  . LEU A 1 92  ? 24.71258  2.09899   -15.56044 1.000 44.06932  ? 72  LEU A HB2  1 
ATOM   1068 H  HB3  . LEU A 1 92  ? 25.91894  2.30041   -14.54578 1.000 44.06932  ? 72  LEU A HB3  1 
ATOM   1069 H  HG   . LEU A 1 92  ? 23.24614  3.07051   -14.02655 1.000 45.73702  ? 72  LEU A HG   1 
ATOM   1070 H  HD11 . LEU A 1 92  ? 23.24902  1.43250   -12.42645 1.000 53.42846  ? 72  LEU A HD11 1 
ATOM   1071 H  HD12 . LEU A 1 92  ? 23.53475  0.79560   -13.85341 1.000 53.42846  ? 72  LEU A HD12 1 
ATOM   1072 H  HD13 . LEU A 1 92  ? 24.72972  1.02442   -12.83205 1.000 53.42846  ? 72  LEU A HD13 1 
ATOM   1073 H  HD21 . LEU A 1 92  ? 24.04636  3.71723   -11.90665 1.000 57.64587  ? 72  LEU A HD21 1 
ATOM   1074 H  HD22 . LEU A 1 92  ? 25.52594  3.35567   -12.35789 1.000 57.64587  ? 72  LEU A HD22 1 
ATOM   1075 H  HD23 . LEU A 1 92  ? 24.76345  4.57263   -13.03696 1.000 57.64587  ? 72  LEU A HD23 1 
ATOM   1076 N  N    . PRO A 1 93  ? 27.71598  3.53855   -16.38587 1.000 32.57955  ? 73  PRO A N    1 
ATOM   1077 C  CA   . PRO A 1 93  ? 28.73938  3.27321   -17.42126 1.000 36.33313  ? 73  PRO A CA   1 
ATOM   1078 C  C    . PRO A 1 93  ? 28.80278  1.80233   -17.82119 1.000 35.17584  ? 73  PRO A C    1 
ATOM   1079 O  O    . PRO A 1 93  ? 29.78477  1.08737   -17.57694 1.000 34.10414  ? 73  PRO A O    1 
ATOM   1080 C  CB   . PRO A 1 93  ? 30.02610  3.74899   -16.73477 1.000 36.68901  ? 73  PRO A CB   1 
ATOM   1081 C  CG   . PRO A 1 93  ? 29.77500  3.54545   -15.30987 1.000 36.15748  ? 73  PRO A CG   1 
ATOM   1082 C  CD   . PRO A 1 93  ? 28.31407  3.78214   -15.05515 1.000 36.21460  ? 73  PRO A CD   1 
ATOM   1083 H  HA   . PRO A 1 93  ? 28.56354  3.81430   -18.20688 1.000 43.62352  ? 73  PRO A HA   1 
ATOM   1084 H  HB2  . PRO A 1 93  ? 30.77966  3.21764   -17.03598 1.000 44.05058  ? 73  PRO A HB2  1 
ATOM   1085 H  HB3  . PRO A 1 93  ? 30.18107  4.68606   -16.93172 1.000 44.05058  ? 73  PRO A HB3  1 
ATOM   1086 H  HG2  . PRO A 1 93  ? 30.01379  2.63597   -15.07170 1.000 43.41274  ? 73  PRO A HG2  1 
ATOM   1087 H  HG3  . PRO A 1 93  ? 30.31026  4.17338   -14.79985 1.000 43.41274  ? 73  PRO A HG3  1 
ATOM   1088 H  HD2  . PRO A 1 93  ? 27.96905  3.15738   -14.39823 1.000 43.48128  ? 73  PRO A HD2  1 
ATOM   1089 H  HD3  . PRO A 1 93  ? 28.15431  4.69307   -14.76260 1.000 43.48128  ? 73  PRO A HD3  1 
ATOM   1090 N  N    . MET A 1 94  ? 27.74433  1.33446   -18.47346 1.000 30.95111  ? 74  MET A N    1 
ATOM   1091 C  CA   . MET A 1 94  ? 27.63768  -0.04289  -18.95574 1.000 27.62281  ? 74  MET A CA   1 
ATOM   1092 C  C    . MET A 1 94  ? 26.95585  -0.05046  -20.31025 1.000 25.55514  ? 74  MET A C    1 
ATOM   1093 O  O    . MET A 1 94  ? 26.30932  0.92567   -20.69461 1.000 27.68936  ? 74  MET A O    1 
ATOM   1094 C  CB   . MET A 1 94  ? 26.94343  -0.93481  -17.91581 1.000 34.49228  ? 74  MET A CB   1 
ATOM   1095 C  CG   . MET A 1 94  ? 25.89900  -0.29324  -17.06426 1.000 40.90931  ? 74  MET A CG   1 
ATOM   1096 S  SD   . MET A 1 94  ? 24.77153  -1.48938  -16.29056 1.000 36.25578  ? 74  MET A SD   1 
ATOM   1097 C  CE   . MET A 1 94  ? 25.44636  -1.84841  -14.74547 1.000 37.74987  ? 74  MET A CE   1 
ATOM   1098 H  H    . MET A 1 94  ? 27.05073  1.80890   -18.65630 1.000 37.16509  ? 74  MET A H    1 
ATOM   1099 H  HA   . MET A 1 94  ? 28.51787  -0.42565  -19.09593 1.000 33.17114  ? 74  MET A HA   1 
ATOM   1100 H  HB2  . MET A 1 94  ? 26.51377  -1.66559  -18.38725 1.000 41.41449  ? 74  MET A HB2  1 
ATOM   1101 H  HB3  . MET A 1 94  ? 27.62319  -1.28072  -17.31651 1.000 41.41449  ? 74  MET A HB3  1 
ATOM   1102 H  HG2  . MET A 1 94  ? 26.33434  0.20695   -16.35632 1.000 49.11493  ? 74  MET A HG2  1 
ATOM   1103 H  HG3  . MET A 1 94  ? 25.36821  0.30391   -17.61433 1.000 49.11493  ? 74  MET A HG3  1 
ATOM   1104 H  HE1  . MET A 1 94  ? 24.89054  -2.50950  -14.30399 1.000 45.32361  ? 74  MET A HE1  1 
ATOM   1105 H  HE2  . MET A 1 94  ? 26.34325  -2.19763  -14.86601 1.000 45.32361  ? 74  MET A HE2  1 
ATOM   1106 H  HE3  . MET A 1 94  ? 25.47618  -1.03539  -14.21724 1.000 45.32361  ? 74  MET A HE3  1 
ATOM   1107 N  N    . MET A 1 95  ? 27.16285  -1.17713  -21.03080 1.000 25.56993  ? 75  MET A N    1 
ATOM   1108 C  CA   A MET A 1 95  ? 26.70939  -1.35035  -22.41535 0.336 25.98553  ? 75  MET A CA   1 
ATOM   1109 C  CA   B MET A 1 95  ? 26.73863  -1.27908  -22.43368 0.664 25.84829  ? 75  MET A CA   1 
ATOM   1110 C  C    . MET A 1 95  ? 25.26750  -0.91955  -22.60117 1.000 25.84685  ? 75  MET A C    1 
ATOM   1111 O  O    . MET A 1 95  ? 24.89765  -0.28291  -23.60068 1.000 25.39705  ? 75  MET A O    1 
ATOM   1112 C  CB   A MET A 1 95  ? 26.81500  -2.83463  -22.74007 0.336 28.32671  ? 75  MET A CB   1 
ATOM   1113 C  CB   B MET A 1 95  ? 27.05251  -2.65399  -23.03127 0.664 28.35220  ? 75  MET A CB   1 
ATOM   1114 C  CG   A MET A 1 95  ? 27.19411  -3.28150  -24.10012 0.336 28.83356  ? 75  MET A CG   1 
ATOM   1115 C  CG   B MET A 1 95  ? 26.12124  -3.77995  -22.74312 0.664 26.58499  ? 75  MET A CG   1 
ATOM   1116 S  SD   A MET A 1 95  ? 26.71562  -5.02458  -24.18503 0.336 24.47228  ? 75  MET A SD   1 
ATOM   1117 S  SD   B MET A 1 95  ? 26.39509  -5.18485  -23.86744 0.664 23.88063  ? 75  MET A SD   1 
ATOM   1118 C  CE   A MET A 1 95  ? 27.97861  -5.79642  -23.17410 0.336 26.53691  ? 75  MET A CE   1 
ATOM   1119 C  CE   B MET A 1 95  ? 27.92956  -5.75585  -23.14338 0.664 26.46695  ? 75  MET A CE   1 
ATOM   1120 H  H    . MET A 1 95  ? 27.54318  -1.88788  -20.73115 1.000 30.70767  ? 75  MET A H    1 
ATOM   1121 H  HA   . MET A 1 95  ? 27.26841  -0.81883  -23.00347 1.000 31.04171  ? 75  MET A HA   1 
ATOM   1122 H  HB2  A MET A 1 95  ? 27.47843  -3.21122  -22.14096 0.336 34.01581  ? 75  MET A HB2  1 
ATOM   1123 H  HB2  B MET A 1 95  ? 27.07756  -2.55623  -23.99600 0.664 34.04640  ? 75  MET A HB2  1 
ATOM   1124 H  HB3  A MET A 1 95  ? 25.94630  -3.22799  -22.56252 0.336 34.01581  ? 75  MET A HB3  1 
ATOM   1125 H  HB3  B MET A 1 95  ? 27.92388  -2.92521  -22.70255 0.664 34.04640  ? 75  MET A HB3  1 
ATOM   1126 H  HG2  A MET A 1 95  ? 26.71549  -2.77440  -24.77442 0.336 34.62404  ? 75  MET A HG2  1 
ATOM   1127 H  HG2  B MET A 1 95  ? 26.26123  -4.08630  -21.83348 0.664 31.92575  ? 75  MET A HG2  1 
ATOM   1128 H  HG3  A MET A 1 95  ? 28.15055  -3.19454  -24.23636 0.336 34.62404  ? 75  MET A HG3  1 
ATOM   1129 H  HG3  B MET A 1 95  ? 25.20695  -3.47539  -22.85363 0.664 31.92575  ? 75  MET A HG3  1 
ATOM   1130 H  HE1  A MET A 1 95  ? 27.78291  -6.74295  -23.09233 0.336 31.86806  ? 75  MET A HE1  1 
ATOM   1131 H  HE1  B MET A 1 95  ? 28.63953  -5.13901  -23.38075 0.664 31.78410  ? 75  MET A HE1  1 
ATOM   1132 H  HE2  A MET A 1 95  ? 28.84207  -5.67263  -23.59839 0.336 31.86806  ? 75  MET A HE2  1 
ATOM   1133 H  HE2  B MET A 1 95  ? 27.83010  -5.79048  -22.17912 0.664 31.78410  ? 75  MET A HE2  1 
ATOM   1134 H  HE3  A MET A 1 95  ? 27.97842  -5.38165  -22.29725 0.336 31.86806  ? 75  MET A HE3  1 
ATOM   1135 H  HE3  B MET A 1 95  ? 28.13109  -6.64024  -23.48711 0.664 31.78410  ? 75  MET A HE3  1 
ATOM   1136 N  N    . ILE A 1 96  ? 24.42559  -1.30900  -21.66051 1.000 22.46147  ? 76  ILE A N    1 
ATOM   1137 C  CA   . ILE A 1 96  ? 22.99643  -1.15411  -21.85630 1.000 23.43379  ? 76  ILE A CA   1 
ATOM   1138 C  C    . ILE A 1 96  ? 22.58701  0.29733   -21.77960 1.000 23.31608  ? 76  ILE A C    1 
ATOM   1139 O  O    . ILE A 1 96  ? 21.49489  0.64171   -22.24407 1.000 23.93926  ? 76  ILE A O    1 
ATOM   1140 C  CB   . ILE A 1 96  ? 22.24853  -2.05306  -20.85292 1.000 19.63683  ? 76  ILE A CB   1 
ATOM   1141 C  CG1  . ILE A 1 96  ? 20.80656  -2.29409  -21.31887 1.000 21.60470  ? 76  ILE A CG1  1 
ATOM   1142 C  CG2  . ILE A 1 96  ? 22.24157  -1.48189  -19.44984 1.000 22.12261  ? 76  ILE A CG2  1 
ATOM   1143 C  CD1  . ILE A 1 96  ? 20.08984  -3.42381  -20.53240 1.000 21.50194  ? 76  ILE A CD1  1 
ATOM   1144 H  H    . ILE A 1 96  ? 24.65219  -1.66131  -20.90942 1.000 26.97752  ? 76  ILE A H    1 
ATOM   1145 H  HA   . ILE A 1 96  ? 22.74443  -1.45155  -22.74452 1.000 28.14431  ? 76  ILE A HA   1 
ATOM   1146 H  HB   . ILE A 1 96  ? 22.73088  -2.89419  -20.82571 1.000 23.58795  ? 76  ILE A HB   1 
ATOM   1147 H  HG12 . ILE A 1 96  ? 20.29715  -1.47743  -21.19860 1.000 25.94940  ? 76  ILE A HG12 1 
ATOM   1148 H  HG13 . ILE A 1 96  ? 20.81709  -2.54354  -22.25619 1.000 25.94940  ? 76  ILE A HG13 1 
ATOM   1149 H  HG21 . ILE A 1 96  ? 21.98323  -2.17872  -18.82648 1.000 26.57090  ? 76  ILE A HG21 1 
ATOM   1150 H  HG22 . ILE A 1 96  ? 23.13104  -1.15960  -19.23566 1.000 26.57090  ? 76  ILE A HG22 1 
ATOM   1151 H  HG23 . ILE A 1 96  ? 21.60609  -0.75013  -19.40992 1.000 26.57090  ? 76  ILE A HG23 1 
ATOM   1152 H  HD11 . ILE A 1 96  ? 19.20215  -3.55170  -20.90191 1.000 25.82609  ? 76  ILE A HD11 1 
ATOM   1153 H  HD12 . ILE A 1 96  ? 20.60400  -4.24207  -20.61605 1.000 25.82609  ? 76  ILE A HD12 1 
ATOM   1154 H  HD13 . ILE A 1 96  ? 20.02584  -3.16732  -19.59912 1.000 25.82609  ? 76  ILE A HD13 1 
ATOM   1155 N  N    . ASP A 1 97  ? 23.41906  1.17336   -21.23428 1.000 23.94106  ? 77  ASP A N    1 
ATOM   1156 C  CA   . ASP A 1 97  ? 23.14093  2.60551   -21.16497 1.000 25.55185  ? 77  ASP A CA   1 
ATOM   1157 C  C    . ASP A 1 97  ? 23.98777  3.40853   -22.15161 1.000 26.65025  ? 77  ASP A C    1 
ATOM   1158 O  O    . ASP A 1 97  ? 24.29483  4.57932   -21.90787 1.000 28.51370  ? 77  ASP A O    1 
ATOM   1159 C  CB   . ASP A 1 97  ? 23.38157  3.12667   -19.74689 1.000 28.06601  ? 77  ASP A CB   1 
ATOM   1160 C  CG   . ASP A 1 97  ? 22.34400  2.68811   -18.74914 1.000 28.96484  ? 77  ASP A CG   1 
ATOM   1161 O  OD1  . ASP A 1 97  ? 21.29011  2.15496   -19.13802 1.000 26.88110  ? 77  ASP A OD1  1 
ATOM   1162 O  OD2  . ASP A 1 97  ? 22.57468  2.88408   -17.53914 1.000 31.18505  ? 77  ASP A OD2  1 
ATOM   1163 H  H    . ASP A 1 97  ? 24.17537  0.95795   -20.88615 1.000 28.75304  ? 77  ASP A H    1 
ATOM   1164 H  HA   . ASP A 1 97  ? 22.20780  2.73876   -21.39390 1.000 30.68598  ? 77  ASP A HA   1 
ATOM   1165 H  HB2  . ASP A 1 97  ? 24.24237  2.80315   -19.43826 1.000 33.70298  ? 77  ASP A HB2  1 
ATOM   1166 H  HB3  . ASP A 1 97  ? 23.37946  4.09646   -19.76713 1.000 33.70298  ? 77  ASP A HB3  1 
ATOM   1167 N  N    . MET A 1 98  ? 24.39366  2.78319   -23.25507 1.000 26.33500  ? 78  MET A N    1 
ATOM   1168 C  CA   . MET A 1 98  ? 25.19002  3.39772   -24.29712 1.000 26.37269  ? 78  MET A CA   1 
ATOM   1169 C  C    . MET A 1 98  ? 24.53601  3.26251   -25.66456 1.000 25.58594  ? 78  MET A C    1 
ATOM   1170 O  O    . MET A 1 98  ? 23.78851  2.32328   -25.92858 1.000 25.28741  ? 78  MET A O    1 
ATOM   1171 C  CB   . MET A 1 98  ? 26.58483  2.77425   -24.36115 1.000 31.33742  ? 78  MET A CB   1 
ATOM   1172 C  CG   . MET A 1 98  ? 27.36800  2.89568   -23.07058 1.000 32.28764  ? 78  MET A CG   1 
ATOM   1173 S  SD   . MET A 1 98  ? 28.84640  1.86336   -22.96371 1.000 34.47940  ? 78  MET A SD   1 
ATOM   1174 C  CE   . MET A 1 98  ? 29.81648  2.61035   -24.24961 1.000 37.34927  ? 78  MET A CE   1 
ATOM   1175 H  H    . MET A 1 98  ? 24.20749  1.96101   -23.42527 1.000 31.62576  ? 78  MET A H    1 
ATOM   1176 H  HA   . MET A 1 98  ? 25.26089  4.34301   -24.09145 1.000 31.67099  ? 78  MET A HA   1 
ATOM   1177 H  HB2  . MET A 1 98  ? 26.49519  1.83022   -24.56531 1.000 37.62867  ? 78  MET A HB2  1 
ATOM   1178 H  HB3  . MET A 1 98  ? 27.09275  3.21771   -25.05847 1.000 37.62867  ? 78  MET A HB3  1 
ATOM   1179 H  HG2  . MET A 1 98  ? 27.65161  3.81784   -22.97023 1.000 38.76894  ? 78  MET A HG2  1 
ATOM   1180 H  HG3  . MET A 1 98  ? 26.78702  2.64537   -22.33525 1.000 38.76894  ? 78  MET A HG3  1 
ATOM   1181 H  HE1  . MET A 1 98  ? 30.66562  2.14600   -24.31482 1.000 44.84289  ? 78  MET A HE1  1 
ATOM   1182 H  HE2  . MET A 1 98  ? 29.33573  2.54008   -25.08916 1.000 44.84289  ? 78  MET A HE2  1 
ATOM   1183 H  HE3  . MET A 1 98  ? 29.96571  3.54353   -24.03100 1.000 44.84289  ? 78  MET A HE3  1 
ATOM   1184 N  N    . ASP A 1 99  ? 24.84114  4.22391   -26.52901 1.000 29.19911  ? 79  ASP A N    1 
ATOM   1185 C  CA   . ASP A 1 99  ? 24.48520  4.17566   -27.94242 1.000 27.92310  ? 79  ASP A CA   1 
ATOM   1186 C  C    . ASP A 1 99  ? 25.70434  3.83802   -28.78937 1.000 27.65173  ? 79  ASP A C    1 
ATOM   1187 O  O    . ASP A 1 99  ? 26.85966  4.03150   -28.37471 1.000 28.98076  ? 79  ASP A O    1 
ATOM   1188 C  CB   . ASP A 1 99  ? 23.88620  5.49983   -28.41910 1.000 32.10534  ? 79  ASP A CB   1 
ATOM   1189 C  CG   . ASP A 1 99  ? 22.60263  5.91497   -27.69634 1.000 27.09857  ? 79  ASP A CG   1 
ATOM   1190 O  OD1  . ASP A 1 99  ? 21.82254  5.01388   -27.30092 1.000 25.61121  ? 79  ASP A OD1  1 
ATOM   1191 O  OD2  . ASP A 1 99  ? 22.33466  7.14790   -27.60247 1.000 29.94879  ? 79  ASP A OD2  1 
ATOM   1192 H  H    . ASP A 1 99  ? 25.26853  4.93834   -26.31331 1.000 35.06269  ? 79  ASP A H    1 
ATOM   1193 H  HA   . ASP A 1 99  ? 23.81592  3.48437   -28.06525 1.000 33.53149  ? 79  ASP A HA   1 
ATOM   1194 H  HB2  . ASP A 1 99  ? 24.54011  6.20265   -28.28003 1.000 38.55017  ? 79  ASP A HB2  1 
ATOM   1195 H  HB3  . ASP A 1 99  ? 23.67785  5.42263   -29.36331 1.000 38.55017  ? 79  ASP A HB3  1 
ATOM   1196 N  N    . ASP A 1 100 ? 25.42663  3.35894   -30.00604 1.000 33.24888  ? 80  ASP A N    1 
ATOM   1197 C  CA   . ASP A 1 100 ? 26.47154  3.18312   -31.00557 1.000 32.52040  ? 80  ASP A CA   1 
ATOM   1198 C  C    . ASP A 1 100 ? 27.04373  4.53999   -31.42698 1.000 35.85999  ? 80  ASP A C    1 
ATOM   1199 O  O    . ASP A 1 100 ? 26.33823  5.55269   -31.41261 1.000 36.05714  ? 80  ASP A O    1 
ATOM   1200 C  CB   . ASP A 1 100 ? 25.90824  2.44082   -32.21892 1.000 32.63359  ? 80  ASP A CB   1 
ATOM   1201 C  CG   . ASP A 1 100 ? 25.59676  0.98099   -31.92339 1.000 35.55665  ? 80  ASP A CG   1 
ATOM   1202 O  OD1  . ASP A 1 100 ? 26.10953  0.43577   -30.94544 1.000 31.92007  ? 80  ASP A OD1  1 
ATOM   1203 O  OD2  . ASP A 1 100 ? 24.86954  0.33261   -32.69263 1.000 42.40737  ? 80  ASP A OD2  1 
ATOM   1204 H  H    . ASP A 1 100 ? 24.64187  3.12997   -30.27309 1.000 39.92241  ? 80  ASP A H    1 
ATOM   1205 H  HA   . ASP A 1 100 ? 27.20025  2.65880   -30.63819 1.000 39.04825  ? 80  ASP A HA   1 
ATOM   1206 H  HB2  . ASP A 1 100 ? 25.08597  2.87209   -32.49959 1.000 39.18407  ? 80  ASP A HB2  1 
ATOM   1207 H  HB3  . ASP A 1 100 ? 26.55958  2.46909   -32.93715 1.000 39.18407  ? 80  ASP A HB3  1 
ATOM   1208 N  N    . PRO A 1 101 ? 28.34112  4.59710   -31.79515 1.000 36.36402  ? 81  PRO A N    1 
ATOM   1209 C  CA   . PRO A 1 101 ? 29.21086  3.42267   -31.93389 1.000 32.88486  ? 81  PRO A CA   1 
ATOM   1210 C  C    . PRO A 1 101 ? 29.86990  2.91102   -30.64843 1.000 39.44816  ? 81  PRO A C    1 
ATOM   1211 O  O    . PRO A 1 101 ? 30.38879  1.79430   -30.68551 1.000 35.24865  ? 81  PRO A O    1 
ATOM   1212 C  CB   . PRO A 1 101 ? 30.30273  3.91296   -32.90830 1.000 38.91179  ? 81  PRO A CB   1 
ATOM   1213 C  CG   . PRO A 1 101 ? 30.44372  5.36593   -32.52813 1.000 39.03459  ? 81  PRO A CG   1 
ATOM   1214 C  CD   . PRO A 1 101 ? 29.04612  5.84387   -32.17058 1.000 38.09265  ? 81  PRO A CD   1 
ATOM   1215 H  HA   . PRO A 1 101 ? 28.68421  2.69956   -32.30892 1.000 39.48559  ? 81  PRO A HA   1 
ATOM   1216 H  HB2  . PRO A 1 101 ? 31.12936  3.42537   -32.76748 1.000 46.71791  ? 81  PRO A HB2  1 
ATOM   1217 H  HB3  . PRO A 1 101 ? 30.01007  3.81134   -33.82749 1.000 46.71791  ? 81  PRO A HB3  1 
ATOM   1218 H  HG2  . PRO A 1 101 ? 31.03929  5.44783   -31.76689 1.000 46.86527  ? 81  PRO A HG2  1 
ATOM   1219 H  HG3  . PRO A 1 101 ? 30.79564  5.86743   -33.28016 1.000 46.86527  ? 81  PRO A HG3  1 
ATOM   1220 H  HD2  . PRO A 1 101 ? 29.07392  6.46228   -31.42379 1.000 45.73494  ? 81  PRO A HD2  1 
ATOM   1221 H  HD3  . PRO A 1 101 ? 28.61992  6.26431   -32.93379 1.000 45.73494  ? 81  PRO A HD3  1 
ATOM   1222 N  N    . ALA A 1 102 ? 29.85844  3.69140   -29.56186 1.000 34.96929  ? 82  ALA A N    1 
ATOM   1223 C  CA   . ALA A 1 102 ? 30.53463  3.25323   -28.34706 1.000 36.25844  ? 82  ALA A CA   1 
ATOM   1224 C  C    . ALA A 1 102 ? 29.94668  1.95272   -27.83713 1.000 33.93257  ? 82  ALA A C    1 
ATOM   1225 O  O    . ALA A 1 102 ? 30.67835  1.07152   -27.36122 1.000 32.52842  ? 82  ALA A O    1 
ATOM   1226 C  CB   . ALA A 1 102 ? 30.44986  4.31614   -27.25736 1.000 33.87009  ? 82  ALA A CB   1 
ATOM   1227 H  H    . ALA A 1 102 ? 29.47489  4.45918   -29.50718 1.000 41.98691  ? 82  ALA A H    1 
ATOM   1228 H  HA   . ALA A 1 102 ? 31.47148  3.11836   -28.55921 1.000 43.53389  ? 82  ALA A HA   1 
ATOM   1229 H  HB1  . ALA A 1 102 ? 30.93537  4.00726   -26.47648 1.000 40.66787  ? 82  ALA A HB1  1 
ATOM   1230 H  HB2  . ALA A 1 102 ? 30.84344  5.13895   -27.58749 1.000 40.66787  ? 82  ALA A HB2  1 
ATOM   1231 H  HB3  . ALA A 1 102 ? 29.51811  4.46271   -27.03096 1.000 40.66787  ? 82  ALA A HB3  1 
ATOM   1232 N  N    . HIS A 1 103 ? 28.61813  1.83149   -27.89815 1.000 29.35773  ? 83  HIS A N    1 
ATOM   1233 C  CA   . HIS A 1 103 ? 27.96281  0.61159   -27.43651 1.000 25.80469  ? 83  HIS A CA   1 
ATOM   1234 C  C    . HIS A 1 103 ? 28.46151  -0.61547  -28.19919 1.000 28.66579  ? 83  HIS A C    1 
ATOM   1235 O  O    . HIS A 1 103 ? 28.63773  -1.69875  -27.61508 1.000 29.09244  ? 83  HIS A O    1 
ATOM   1236 C  CB   . HIS A 1 103 ? 26.45363  0.73463   -27.61829 1.000 26.98797  ? 83  HIS A CB   1 
ATOM   1237 C  CG   . HIS A 1 103 ? 25.75525  -0.58538  -27.65250 1.000 25.55757  ? 83  HIS A CG   1 
ATOM   1238 N  ND1  . HIS A 1 103 ? 25.49559  -1.24852  -28.83039 1.000 27.35728  ? 83  HIS A ND1  1 
ATOM   1239 C  CD2  . HIS A 1 103 ? 25.26626  -1.37035  -26.65957 1.000 25.32562  ? 83  HIS A CD2  1 
ATOM   1240 C  CE1  . HIS A 1 103 ? 24.86105  -2.38012  -28.56626 1.000 26.79106  ? 83  HIS A CE1  1 
ATOM   1241 N  NE2  . HIS A 1 103 ? 24.73537  -2.49337  -27.25689 1.000 25.87279  ? 83  HIS A NE2  1 
ATOM   1242 H  H    . HIS A 1 103 ? 28.08229  2.43332   -28.19860 1.000 35.25304  ? 83  HIS A H    1 
ATOM   1243 H  HA   . HIS A 1 103 ? 28.16385  0.49591   -26.49465 1.000 30.98939  ? 83  HIS A HA   1 
ATOM   1244 H  HB2  . HIS A 1 103 ? 26.08898  1.24605   -26.87912 1.000 32.40933  ? 83  HIS A HB2  1 
ATOM   1245 H  HB3  . HIS A 1 103 ? 26.27431  1.18887   -28.45639 1.000 32.40933  ? 83  HIS A HB3  1 
ATOM   1246 H  HD1  . HIS A 1 103 ? 25.71174  -0.97116  -29.61522 1.000 32.85249  ? 83  HIS A HD1  1 
ATOM   1247 H  HD2  . HIS A 1 103 ? 25.28566  -1.18557  -25.74832 1.000 30.41451  ? 83  HIS A HD2  1 
ATOM   1248 H  HE1  . HIS A 1 103 ? 24.55548  -2.99187  -29.19658 1.000 32.17303  ? 83  HIS A HE1  1 
ATOM   1249 H  HE2  . HIS A 1 103 ? 24.38029  -3.15906  -26.84412 1.000 31.07110  ? 83  HIS A HE2  1 
ATOM   1250 N  N    . LEU A 1 104 ? 28.61329  -0.48598  -29.51905 1.000 29.81770  ? 84  LEU A N    1 
ATOM   1251 C  CA   . LEU A 1 104 ? 28.99785  -1.64464  -30.32052 1.000 35.56488  ? 84  LEU A CA   1 
ATOM   1252 C  C    . LEU A 1 104 ? 30.37623  -2.16795  -29.92095 1.000 33.56893  ? 84  LEU A C    1 
ATOM   1253 O  O    . LEU A 1 104 ? 30.59364  -3.38516  -29.86976 1.000 33.54022  ? 84  LEU A O    1 
ATOM   1254 C  CB   . LEU A 1 104 ? 28.99826  -1.27740  -31.80041 1.000 41.07356  ? 84  LEU A CB   1 
ATOM   1255 C  CG   . LEU A 1 104 ? 29.12762  -2.45215  -32.77453 1.000 40.77106  ? 84  LEU A CG   1 
ATOM   1256 C  CD1  . LEU A 1 104 ? 28.14980  -3.54619  -32.44431 1.000 45.83430  ? 84  LEU A CD1  1 
ATOM   1257 C  CD2  . LEU A 1 104 ? 28.93959  -1.95829  -34.20987 1.000 46.43835  ? 84  LEU A CD2  1 
ATOM   1258 H  H    . LEU A 1 104 ? 28.50232  0.24269   -29.96214 1.000 35.80500  ? 84  LEU A H    1 
ATOM   1259 H  HA   . LEU A 1 104 ? 28.34691  -2.34841  -30.17260 1.000 42.70162  ? 84  LEU A HA   1 
ATOM   1260 H  HB2  . LEU A 1 104 ? 28.16366  -0.82593  -32.00167 1.000 49.31203  ? 84  LEU A HB2  1 
ATOM   1261 H  HB3  . LEU A 1 104 ? 29.74584  -0.68175  -31.96544 1.000 49.31203  ? 84  LEU A HB3  1 
ATOM   1262 H  HG   . LEU A 1 104 ? 30.01531  -2.83511  -32.69557 1.000 48.94904  ? 84  LEU A HG   1 
ATOM   1263 H  HD11 . LEU A 1 104 ? 28.21477  -4.24158  -33.11745 1.000 55.02492  ? 84  LEU A HD11 1 
ATOM   1264 H  HD12 . LEU A 1 104 ? 28.36561  -3.90971  -31.57129 1.000 55.02492  ? 84  LEU A HD12 1 
ATOM   1265 H  HD13 . LEU A 1 104 ? 27.25308  -3.17643  -32.43620 1.000 55.02492  ? 84  LEU A HD13 1 
ATOM   1266 H  HD21 . LEU A 1 104 ? 29.04805  -2.70621  -34.81794 1.000 55.74978  ? 84  LEU A HD21 1 
ATOM   1267 H  HD22 . LEU A 1 104 ? 28.04926  -1.58426  -34.30107 1.000 55.74978  ? 84  LEU A HD22 1 
ATOM   1268 H  HD23 . LEU A 1 104 ? 29.60499  -1.27850  -34.39967 1.000 55.74978  ? 84  LEU A HD23 1 
ATOM   1269 N  N    . LEU A 1 105 ? 31.32104  -1.26494  -29.66188 1.000 31.09437  ? 85  LEU A N    1 
ATOM   1270 C  CA   . LEU A 1 105 ? 32.66141  -1.67694  -29.22928 1.000 30.88290  ? 85  LEU A CA   1 
ATOM   1271 C  C    . LEU A 1 105 ? 32.58722  -2.40340  -27.89357 1.000 31.57811  ? 85  LEU A C    1 
ATOM   1272 O  O    . LEU A 1 105 ? 33.19993  -3.45908  -27.70028 1.000 31.20599  ? 85  LEU A O    1 
ATOM   1273 C  CB   . LEU A 1 105 ? 33.58392  -0.46556  -29.13217 1.000 34.83172  ? 85  LEU A CB   1 
ATOM   1274 C  CG   . LEU A 1 105 ? 34.94444  -0.81576  -28.51024 1.000 36.44012  ? 85  LEU A CG   1 
ATOM   1275 C  CD1  . LEU A 1 105 ? 35.68325  -1.84661  -29.33694 1.000 41.25267  ? 85  LEU A CD1  1 
ATOM   1276 C  CD2  . LEU A 1 105 ? 35.79011  0.46141   -28.37068 1.000 38.59085  ? 85  LEU A CD2  1 
ATOM   1277 H  H    . LEU A 1 105 ? 31.21620  -0.41386  -29.72717 1.000 37.33701  ? 85  LEU A H    1 
ATOM   1278 H  HA   . LEU A 1 105 ? 33.03619  -2.27919  -29.89090 1.000 37.08324  ? 85  LEU A HA   1 
ATOM   1279 H  HB2  . LEU A 1 105 ? 33.73963  -0.11395  -30.02269 1.000 41.82183  ? 85  LEU A HB2  1 
ATOM   1280 H  HB3  . LEU A 1 105 ? 33.16248  0.20974   -28.57786 1.000 41.82183  ? 85  LEU A HB3  1 
ATOM   1281 H  HG   . LEU A 1 105 ? 34.79889  -1.20149  -27.63221 1.000 43.75190  ? 85  LEU A HG   1 
ATOM   1282 H  HD11 . LEU A 1 105 ? 36.53691  -2.03549  -28.91684 1.000 49.52697  ? 85  LEU A HD11 1 
ATOM   1283 H  HD12 . LEU A 1 105 ? 35.15054  -2.65598  -29.38210 1.000 49.52697  ? 85  LEU A HD12 1 
ATOM   1284 H  HD13 . LEU A 1 105 ? 35.82465  -1.49347  -30.22924 1.000 49.52697  ? 85  LEU A HD13 1 
ATOM   1285 H  HD21 . LEU A 1 105 ? 36.65334  0.22901   -27.99421 1.000 46.33278  ? 85  LEU A HD21 1 
ATOM   1286 H  HD22 . LEU A 1 105 ? 35.90793  0.85951   -29.24734 1.000 46.33278  ? 85  LEU A HD22 1 
ATOM   1287 H  HD23 . LEU A 1 105 ? 35.32996  1.08237   -27.78454 1.000 46.33278  ? 85  LEU A HD23 1 
ATOM   1288 N  N    . ARG A 1 106 ? 31.83534  -1.83810  -26.95060 1.000 31.25146  ? 86  ARG A N    1 
ATOM   1289 C  CA   . ARG A 1 106 ? 31.69913  -2.46920  -25.64353 1.000 28.58301  ? 86  ARG A CA   1 
ATOM   1290 C  C    . ARG A 1 106 ? 31.06389  -3.83910  -25.76217 1.000 30.52431  ? 86  ARG A C    1 
ATOM   1291 O  O    . ARG A 1 106 ? 31.50834  -4.80553  -25.13282 1.000 28.82346  ? 86  ARG A O    1 
ATOM   1292 C  CB   . ARG A 1 106 ? 30.86106  -1.57140  -24.72736 1.000 30.30688  ? 86  ARG A CB   1 
ATOM   1293 C  CG   . ARG A 1 106 ? 30.75433  -2.06566  -23.30653 1.000 28.71394  ? 86  ARG A CG   1 
ATOM   1294 C  CD   . ARG A 1 106 ? 32.08653  -1.95683  -22.53343 1.000 31.62340  ? 86  ARG A CD   1 
ATOM   1295 N  NE   . ARG A 1 106 ? 32.54622  -0.57814  -22.40274 1.000 34.32940  ? 86  ARG A NE   1 
ATOM   1296 C  CZ   . ARG A 1 106 ? 32.13213  0.27428   -21.46907 1.000 35.71288  ? 86  ARG A CZ   1 
ATOM   1297 N  NH1  . ARG A 1 106 ? 31.34888  -0.11418  -20.47878 1.000 34.91891  ? 86  ARG A NH1  1 
ATOM   1298 N  NH2  . ARG A 1 106 ? 32.49493  1.55827   -21.54737 1.000 43.31684  ? 86  ARG A NH2  1 
ATOM   1299 H  H    . ARG A 1 106 ? 31.40107  -1.10138  -27.04139 1.000 37.52551  ? 86  ARG A H    1 
ATOM   1300 H  HA   . ARG A 1 106 ? 32.57863  -2.57838  -25.24925 1.000 34.32338  ? 86  ARG A HA   1 
ATOM   1301 H  HB2  . ARG A 1 106 ? 31.26535  -0.69002  -24.70269 1.000 36.39202  ? 86  ARG A HB2  1 
ATOM   1302 H  HB3  . ARG A 1 106 ? 29.96212  -1.51410  -25.08726 1.000 36.39202  ? 86  ARG A HB3  1 
ATOM   1303 H  HG2  . ARG A 1 106 ? 30.09131  -1.53625  -22.83640 1.000 34.48050  ? 86  ARG A HG2  1 
ATOM   1304 H  HG3  . ARG A 1 106 ? 30.48864  -2.99853  -23.31524 1.000 34.48050  ? 86  ARG A HG3  1 
ATOM   1305 H  HD2  . ARG A 1 106 ? 31.96634  -2.31952  -21.64185 1.000 37.97184  ? 86  ARG A HD2  1 
ATOM   1306 H  HD3  . ARG A 1 106 ? 32.76939  -2.45795  -23.00617 1.000 37.97184  ? 86  ARG A HD3  1 
ATOM   1307 H  HE   . ARG A 1 106 ? 33.12716  -0.29606  -22.97067 1.000 41.21904  ? 86  ARG A HE   1 
ATOM   1308 H  HH11 . ARG A 1 106 ? 31.09533  -0.93435  -20.42745 1.000 41.92645  ? 86  ARG A HH11 1 
ATOM   1309 H  HH12 . ARG A 1 106 ? 31.09252  0.45309   -19.88542 1.000 41.92645  ? 86  ARG A HH12 1 
ATOM   1310 H  HH21 . ARG A 1 106 ? 32.99119  1.82606   -22.19668 1.000 52.00397  ? 86  ARG A HH21 1 
ATOM   1311 H  HH22 . ARG A 1 106 ? 32.23210  2.11666   -20.94843 1.000 52.00397  ? 86  ARG A HH22 1 
ATOM   1312 N  N    . ARG A 1 107 ? 30.01580  -3.94116  -26.57444 1.000 27.90021  ? 87  ARG A N    1 
ATOM   1313 C  CA   . ARG A 1 107 ? 29.33928  -5.22164  -26.73919 1.000 26.06369  ? 87  ARG A CA   1 
ATOM   1314 C  C    . ARG A 1 107 ? 30.25667  -6.24794  -27.39628 1.000 28.26217  ? 87  ARG A C    1 
ATOM   1315 O  O    . ARG A 1 107 ? 30.25357  -7.42308  -27.01181 1.000 29.71309  ? 87  ARG A O    1 
ATOM   1316 C  CB   . ARG A 1 107 ? 28.05603  -5.06476  -27.56371 1.000 25.61350  ? 87  ARG A CB   1 
ATOM   1317 C  CG   . ARG A 1 107 ? 27.30831  -6.38805  -27.67798 1.000 29.62120  ? 87  ARG A CG   1 
ATOM   1318 C  CD   . ARG A 1 107 ? 25.95317  -6.21296  -28.28033 1.000 34.99207  ? 87  ARG A CD   1 
ATOM   1319 N  NE   . ARG A 1 107 ? 25.28070  -7.48593  -28.52990 1.000 30.50377  ? 87  ARG A NE   1 
ATOM   1320 C  CZ   . ARG A 1 107 ? 24.05709  -7.77817  -28.12141 1.000 28.34208  ? 87  ARG A CZ   1 
ATOM   1321 N  NH1  . ARG A 1 107 ? 23.36414  -6.93156  -27.38020 1.000 24.98816  ? 87  ARG A NH1  1 
ATOM   1322 N  NH2  . ARG A 1 107 ? 23.52433  -8.96028  -28.45658 1.000 29.18173  ? 87  ARG A NH2  1 
ATOM   1323 H  H    . ARG A 1 107 ? 29.68208  -3.29529  -27.03389 1.000 33.50401  ? 87  ARG A H    1 
ATOM   1324 H  HA   . ARG A 1 107 ? 29.08830  -5.54248  -25.85886 1.000 31.30018  ? 87  ARG A HA   1 
ATOM   1325 H  HB2  . ARG A 1 107 ? 27.47383  -4.41958  -27.13280 1.000 30.75996  ? 87  ARG A HB2  1 
ATOM   1326 H  HB3  . ARG A 1 107 ? 28.28278  -4.76231  -28.45702 1.000 30.75996  ? 87  ARG A HB3  1 
ATOM   1327 H  HG2  . ARG A 1 107 ? 27.81457  -6.99358  -28.24183 1.000 35.56920  ? 87  ARG A HG2  1 
ATOM   1328 H  HG3  . ARG A 1 107 ? 27.19955  -6.77114  -26.79350 1.000 35.56920  ? 87  ARG A HG3  1 
ATOM   1329 H  HD2  . ARG A 1 107 ? 25.40109  -5.69551  -27.67339 1.000 42.01425  ? 87  ARG A HD2  1 
ATOM   1330 H  HD3  . ARG A 1 107 ? 26.04051  -5.74826  -29.12728 1.000 42.01425  ? 87  ARG A HD3  1 
ATOM   1331 H  HE   . ARG A 1 107 ? 25.70956  -8.08583  -28.97239 1.000 36.62829  ? 87  ARG A HE   1 
ATOM   1332 H  HH11 . ARG A 1 107 ? 23.70770  -6.17585  -27.15554 1.000 30.00955  ? 87  ARG A HH11 1 
ATOM   1333 H  HH12 . ARG A 1 107 ? 22.56961  -7.13630  -27.12250 1.000 30.00955  ? 87  ARG A HH12 1 
ATOM   1334 H  HH21 . ARG A 1 107 ? 23.97686  -9.51690  -28.93092 1.000 35.04184  ? 87  ARG A HH21 1 
ATOM   1335 H  HH22 . ARG A 1 107 ? 22.72968  -9.16277  -28.19747 1.000 35.04184  ? 87  ARG A HH22 1 
ATOM   1336 N  N    . LYS A 1 108 ? 31.01955  -5.82433  -28.40725 1.000 28.76885  ? 88  LYS A N    1 
ATOM   1337 C  CA   . LYS A 1 108 ? 31.93858  -6.73935  -29.07007 1.000 30.64962  ? 88  LYS A CA   1 
ATOM   1338 C  C    . LYS A 1 108 ? 32.96298  -7.28047  -28.09035 1.000 34.47189  ? 88  LYS A C    1 
ATOM   1339 O  O    . LYS A 1 108 ? 33.35387  -8.45876  -28.16324 1.000 32.34425  ? 88  LYS A O    1 
ATOM   1340 C  CB   . LYS A 1 108 ? 32.64310  -6.04263  -30.22824 1.000 37.13137  ? 88  LYS A CB   1 
ATOM   1341 C  CG   . LYS A 1 108 ? 31.77529  -5.84884  -31.46211 1.000 44.44740  ? 88  LYS A CG   1 
ATOM   1342 C  CD   . LYS A 1 108 ? 32.63803  -5.25030  -32.59492 1.000 48.16109  ? 88  LYS A CD   1 
ATOM   1343 C  CE   . LYS A 1 108 ? 31.95699  -5.34725  -33.94632 1.000 56.51619  ? 88  LYS A CE   1 
ATOM   1344 N  NZ   . LYS A 1 108 ? 32.35849  -4.18954  -34.83450 1.000 61.65676  ? 88  LYS A NZ   1 
ATOM   1345 H  H    . LYS A 1 108 ? 31.02166  -5.02375  -28.72136 1.000 34.54638  ? 88  LYS A H    1 
ATOM   1346 H  HA   . LYS A 1 108 ? 31.42828  -7.48091  -29.43145 1.000 36.80331  ? 88  LYS A HA   1 
ATOM   1347 H  HB2  . LYS A 1 108 ? 32.93300  -5.16563  -29.93205 1.000 44.58141  ? 88  LYS A HB2  1 
ATOM   1348 H  HB3  . LYS A 1 108 ? 33.41068  -6.57511  -30.48938 1.000 44.58141  ? 88  LYS A HB3  1 
ATOM   1349 H  HG2  . LYS A 1 108 ? 31.42002  -6.70292  -31.75406 1.000 53.36064  ? 88  LYS A HG2  1 
ATOM   1350 H  HG3  . LYS A 1 108 ? 31.04869  -5.23793  -31.26280 1.000 53.36064  ? 88  LYS A HG3  1 
ATOM   1351 H  HD2  . LYS A 1 108 ? 32.80462  -4.31330  -32.40738 1.000 57.81707  ? 88  LYS A HD2  1 
ATOM   1352 H  HD3  . LYS A 1 108 ? 33.47787  -5.73308  -32.64481 1.000 57.81707  ? 88  LYS A HD3  1 
ATOM   1353 H  HE2  . LYS A 1 108 ? 32.21734  -6.17410  -34.38157 1.000 67.84319  ? 88  LYS A HE2  1 
ATOM   1354 H  HE3  . LYS A 1 108 ? 30.99471  -5.32417  -33.82640 1.000 67.84319  ? 88  LYS A HE3  1 
ATOM   1355 H  HZ1  . LYS A 1 108 ? 31.96423  -4.26434  -35.62890 1.000 74.01187  ? 88  LYS A HZ1  1 
ATOM   1356 H  HZ2  . LYS A 1 108 ? 32.11245  -3.41995  -34.46126 1.000 74.01187  ? 88  LYS A HZ2  1 
ATOM   1357 H  HZ3  . LYS A 1 108 ? 33.24105  -4.18574  -34.94927 1.000 74.01187  ? 88  LYS A HZ3  1 
ATOM   1358 N  N    . LEU A 1 109 ? 33.45286  -6.41368  -27.20229 1.000 30.73153  ? 89  LEU A N    1 
ATOM   1359 C  CA   . LEU A 1 109 ? 34.45038  -6.84445  -26.23354 1.000 28.40200  ? 89  LEU A CA   1 
ATOM   1360 C  C    . LEU A 1 109 ? 33.85665  -7.87769  -25.28756 1.000 28.75729  ? 89  LEU A C    1 
ATOM   1361 O  O    . LEU A 1 109 ? 34.48519  -8.90096  -25.00550 1.000 31.62372  ? 89  LEU A O    1 
ATOM   1362 C  CB   . LEU A 1 109 ? 34.97792  -5.63587  -25.45795 1.000 28.77500  ? 89  LEU A CB   1 
ATOM   1363 C  CG   . LEU A 1 109 ? 35.98097  -4.75672  -26.17963 1.000 30.84233  ? 89  LEU A CG   1 
ATOM   1364 C  CD1  . LEU A 1 109 ? 36.13095  -3.41425  -25.49558 1.000 36.08282  ? 89  LEU A CD1  1 
ATOM   1365 C  CD2  . LEU A 1 109 ? 37.34282  -5.44748  -26.25920 1.000 31.94875  ? 89  LEU A CD2  1 
ATOM   1366 H  H    . LEU A 1 109 ? 33.22638  -5.58615  -27.14322 1.000 36.90159  ? 89  LEU A H    1 
ATOM   1367 H  HA   . LEU A 1 109 ? 35.19975  -7.24873  -26.69819 1.000 34.10616  ? 89  LEU A HA   1 
ATOM   1368 H  HB2  . LEU A 1 109 ? 34.22188  -5.07453  -25.22514 1.000 34.55376  ? 89  LEU A HB2  1 
ATOM   1369 H  HB3  . LEU A 1 109 ? 35.41039  -5.96065  -24.65272 1.000 34.55376  ? 89  LEU A HB3  1 
ATOM   1370 H  HG   . LEU A 1 109 ? 35.65246  -4.60270  -27.07922 1.000 37.03456  ? 89  LEU A HG   1 
ATOM   1371 H  HD11 . LEU A 1 109 ? 36.80065  -2.89332  -25.96572 1.000 43.32315  ? 89  LEU A HD11 1 
ATOM   1372 H  HD12 . LEU A 1 109 ? 35.27822  -2.95237  -25.51604 1.000 43.32315  ? 89  LEU A HD12 1 
ATOM   1373 H  HD13 . LEU A 1 109 ? 36.40782  -3.55706  -24.57697 1.000 43.32315  ? 89  LEU A HD13 1 
ATOM   1374 H  HD21 . LEU A 1 109 ? 37.96142  -4.87205  -26.73577 1.000 38.36227  ? 89  LEU A HD21 1 
ATOM   1375 H  HD22 . LEU A 1 109 ? 37.66778  -5.60947  -25.35972 1.000 38.36227  ? 89  LEU A HD22 1 
ATOM   1376 H  HD23 . LEU A 1 109 ? 37.24303  -6.28888  -26.73140 1.000 38.36227  ? 89  LEU A HD23 1 
ATOM   1377 N  N    . VAL A 1 110 ? 32.66860  -7.59774  -24.75162 1.000 26.90833  ? 90  VAL A N    1 
ATOM   1378 C  CA   . VAL A 1 110 ? 32.02812  -8.52569  -23.82201 1.000 25.79852  ? 90  VAL A CA   1 
ATOM   1379 C  C    . VAL A 1 110 ? 31.54775  -9.77837  -24.53529 1.000 29.64820  ? 90  VAL A C    1 
ATOM   1380 O  O    . VAL A 1 110 ? 31.47643  -10.84746 -23.92614 1.000 28.56717  ? 90  VAL A O    1 
ATOM   1381 C  CB   . VAL A 1 110 ? 30.87265  -7.82953  -23.09375 1.000 24.37058  ? 90  VAL A CB   1 
ATOM   1382 C  CG1  . VAL A 1 110 ? 30.11747  -8.80415  -22.18455 1.000 27.36195  ? 90  VAL A CG1  1 
ATOM   1383 C  CG2  . VAL A 1 110 ? 31.39194  -6.61578  -22.33033 1.000 27.37223  ? 90  VAL A CG2  1 
ATOM   1384 H  H    . VAL A 1 110 ? 32.21587  -6.88351  -24.90818 1.000 32.31376  ? 90  VAL A H    1 
ATOM   1385 H  HA   . VAL A 1 110 ? 32.68949  -8.79558  -23.16577 1.000 30.98199  ? 90  VAL A HA   1 
ATOM   1386 H  HB   . VAL A 1 110 ? 30.22910  -7.51379  -23.74724 1.000 29.26846  ? 90  VAL A HB   1 
ATOM   1387 H  HG11 . VAL A 1 110 ? 29.51779  -8.30128  -21.61148 1.000 32.85810  ? 90  VAL A HG11 1 
ATOM   1388 H  HG12 . VAL A 1 110 ? 29.60959  -9.42053  -22.73503 1.000 32.85810  ? 90  VAL A HG12 1 
ATOM   1389 H  HG13 . VAL A 1 110 ? 30.75801  -9.29338  -21.64485 1.000 32.85810  ? 90  VAL A HG13 1 
ATOM   1390 H  HG21 . VAL A 1 110 ? 30.65948  -6.21734  -21.83471 1.000 32.87044  ? 90  VAL A HG21 1 
ATOM   1391 H  HG22 . VAL A 1 110 ? 32.08836  -6.90168  -21.71864 1.000 32.87044  ? 90  VAL A HG22 1 
ATOM   1392 H  HG23 . VAL A 1 110 ? 31.75060  -5.97427  -22.96337 1.000 32.87044  ? 90  VAL A HG23 1 
ATOM   1393 N  N    . ASN A 1 111 ? 31.25595  -9.68268  -25.83226 1.000 29.38144  ? 91  ASN A N    1 
ATOM   1394 C  CA   . ASN A 1 111 ? 30.76488  -10.83941 -26.57005 1.000 32.71750  ? 91  ASN A CA   1 
ATOM   1395 C  C    . ASN A 1 111 ? 31.73641  -12.01227 -26.54041 1.000 32.03336  ? 91  ASN A C    1 
ATOM   1396 O  O    . ASN A 1 111 ? 31.32112  -13.14927 -26.78786 1.000 34.77153  ? 91  ASN A O    1 
ATOM   1397 C  CB   . ASN A 1 111 ? 30.50057  -10.46032 -28.02911 1.000 35.80641  ? 91  ASN A CB   1 
ATOM   1398 C  CG   . ASN A 1 111 ? 29.81986  -11.55601 -28.80415 1.000 42.01833  ? 91  ASN A CG   1 
ATOM   1399 O  OD1  . ASN A 1 111 ? 28.62358  -11.74111 -28.70551 1.000 38.78987  ? 91  ASN A OD1  1 
ATOM   1400 N  ND2  . ASN A 1 111 ? 30.59908  -12.31039 -29.56796 1.000 42.11845  ? 91  ASN A ND2  1 
ATOM   1401 H  H    . ASN A 1 111 ? 31.33332  -8.96626  -26.30168 1.000 35.28148  ? 91  ASN A H    1 
ATOM   1402 H  HA   . ASN A 1 111 ? 29.93191  -11.12056 -26.16016 1.000 39.28476  ? 91  ASN A HA   1 
ATOM   1403 H  HB2  . ASN A 1 111 ? 29.92898  -9.67699  -28.05313 1.000 42.99146  ? 91  ASN A HB2  1 
ATOM   1404 H  HB3  . ASN A 1 111 ? 31.34625  -10.26737 -28.46327 1.000 42.99146  ? 91  ASN A HB3  1 
ATOM   1405 H  HD21 . ASN A 1 111 ? 30.25816  -12.95003 -30.03083 1.000 50.56590  ? 91  ASN A HD21 1 
ATOM   1406 H  HD22 . ASN A 1 111 ? 31.44518  -12.15984 -29.60029 1.000 50.56590  ? 91  ASN A HD22 1 
ATOM   1407 N  N    . ALA A 1 112 ? 33.01471  -11.77354 -26.26427 1.000 31.40110  ? 92  ALA A N    1 
ATOM   1408 C  CA   . ALA A 1 112 ? 33.96527  -12.87626 -26.21502 1.000 34.22360  ? 92  ALA A CA   1 
ATOM   1409 C  C    . ALA A 1 112 ? 33.53434  -13.93324 -25.20681 1.000 34.33954  ? 92  ALA A C    1 
ATOM   1410 O  O    . ALA A 1 112 ? 33.88372  -15.11744 -25.35789 1.000 38.31401  ? 92  ALA A O    1 
ATOM   1411 C  CB   . ALA A 1 112 ? 35.36084  -12.35288 -25.86941 1.000 37.72621  ? 92  ALA A CB   1 
ATOM   1412 H  H    . ALA A 1 112 ? 33.35046  -10.99801 -26.10483 1.000 37.70509  ? 92  ALA A H    1 
ATOM   1413 H  HA   . ALA A 1 112 ? 34.01009  -13.29154 -27.09048 1.000 41.09208  ? 92  ALA A HA   1 
ATOM   1414 H  HB1  . ALA A 1 112 ? 35.97937  -13.09945 -25.83837 1.000 45.29522  ? 92  ALA A HB1  1 
ATOM   1415 H  HB2  . ALA A 1 112 ? 35.63889  -11.72108 -26.55089 1.000 45.29522  ? 92  ALA A HB2  1 
ATOM   1416 H  HB3  . ALA A 1 112 ? 35.32842  -11.91403 -25.00497 1.000 45.29522  ? 92  ALA A HB3  1 
ATOM   1417 N  N    . GLY A 1 113 ? 32.78554  -13.52875 -24.17161 1.000 31.91194  ? 93  GLY A N    1 
ATOM   1418 C  CA   . GLY A 1 113 ? 32.30638  -14.47941 -23.18235 1.000 32.13550  ? 93  GLY A CA   1 
ATOM   1419 C  C    . GLY A 1 113 ? 31.04062  -15.20719 -23.55889 1.000 31.22720  ? 93  GLY A C    1 
ATOM   1420 O  O    . GLY A 1 113 ? 30.60378  -16.10045 -22.81381 1.000 32.98159  ? 93  GLY A O    1 
ATOM   1421 H  H    . GLY A 1 113 ? 32.54780  -12.71481 -24.02816 1.000 38.31809  ? 93  GLY A H    1 
ATOM   1422 H  HA2  . GLY A 1 113 ? 32.99606  -15.14478 -23.03229 1.000 38.58636  ? 93  GLY A HA2  1 
ATOM   1423 H  HA3  . GLY A 1 113 ? 32.13886  -14.00555 -22.35271 1.000 38.58636  ? 93  GLY A HA3  1 
ATOM   1424 N  N    . PHE A 1 114 ? 30.42825  -14.83783 -24.69027 1.000 30.44630  ? 94  PHE A N    1 
ATOM   1425 C  CA   . PHE A 1 114 ? 29.09207  -15.32412 -25.02983 1.000 29.70404  ? 94  PHE A CA   1 
ATOM   1426 C  C    . PHE A 1 114 ? 28.99734  -15.74588 -26.48518 1.000 30.09830  ? 94  PHE A C    1 
ATOM   1427 O  O    . PHE A 1 114 ? 27.91779  -15.65643 -27.10130 1.000 31.06998  ? 94  PHE A O    1 
ATOM   1428 C  CB   . PHE A 1 114 ? 28.03292  -14.26757 -24.69207 1.000 30.29508  ? 94  PHE A CB   1 
ATOM   1429 C  CG   . PHE A 1 114 ? 27.95454  -13.98418 -23.24810 1.000 29.35957  ? 94  PHE A CG   1 
ATOM   1430 C  CD1  . PHE A 1 114 ? 27.10033  -14.70585 -22.44238 1.000 30.09964  ? 94  PHE A CD1  1 
ATOM   1431 C  CD2  . PHE A 1 114 ? 28.79220  -13.02697 -22.66186 1.000 34.33932  ? 94  PHE A CD2  1 
ATOM   1432 C  CE1  . PHE A 1 114 ? 27.07179  -14.47414 -21.06858 1.000 40.96815  ? 94  PHE A CE1  1 
ATOM   1433 C  CE2  . PHE A 1 114 ? 28.75244  -12.79778 -21.30746 1.000 34.93546  ? 94  PHE A CE2  1 
ATOM   1434 C  CZ   . PHE A 1 114 ? 27.90633  -13.52075 -20.51178 1.000 36.97589  ? 94  PHE A CZ   1 
ATOM   1435 H  H    . PHE A 1 114 ? 30.76815  -14.30675 -25.27509 1.000 36.55932  ? 94  PHE A H    1 
ATOM   1436 H  HA   . PHE A 1 114 ? 28.90194  -16.11493 -24.50127 1.000 35.66860  ? 94  PHE A HA   1 
ATOM   1437 H  HB2  . PHE A 1 114 ? 28.25378  -13.44106 -25.14923 1.000 36.37786  ? 94  PHE A HB2  1 
ATOM   1438 H  HB3  . PHE A 1 114 ? 27.16435  -14.58610 -24.98365 1.000 36.37786  ? 94  PHE A HB3  1 
ATOM   1439 H  HD1  . PHE A 1 114 ? 26.54190  -15.34868 -22.81630 1.000 36.14333  ? 94  PHE A HD1  1 
ATOM   1440 H  HD2  . PHE A 1 114 ? 29.38077  -12.54198 -23.19409 1.000 41.23095  ? 94  PHE A HD2  1 
ATOM   1441 H  HE1  . PHE A 1 114 ? 26.49265  -14.95959 -20.52652 1.000 49.18554  ? 94  PHE A HE1  1 
ATOM   1442 H  HE2  . PHE A 1 114 ? 29.30233  -12.14930 -20.93065 1.000 41.94631  ? 94  PHE A HE2  1 
ATOM   1443 H  HZ   . PHE A 1 114 ? 27.89190  -13.37111 -19.59401 1.000 44.39483  ? 94  PHE A HZ   1 
ATOM   1444 N  N    . THR A 1 115 ? 30.10890  -16.21861 -27.04979 1.000 30.45984  ? 95  THR A N    1 
ATOM   1445 C  CA   . THR A 1 115 ? 30.05172  -16.79068 -28.38822 1.000 34.31432  ? 95  THR A CA   1 
ATOM   1446 C  C    . THR A 1 115 ? 29.15908  -18.02658 -28.37543 1.000 34.41056  ? 95  THR A C    1 
ATOM   1447 O  O    . THR A 1 115 ? 28.92297  -18.64015 -27.32489 1.000 32.99875  ? 95  THR A O    1 
ATOM   1448 C  CB   . THR A 1 115 ? 31.42983  -17.16608 -28.87890 1.000 35.95219  ? 95  THR A CB   1 
ATOM   1449 O  OG1  . THR A 1 115 ? 31.96950  -18.17770 -28.04192 1.000 36.06272  ? 95  THR A OG1  1 
ATOM   1450 C  CG2  . THR A 1 115 ? 32.33958  -15.93096 -28.86726 1.000 41.92961  ? 95  THR A CG2  1 
ATOM   1451 H  H    . THR A 1 115 ? 30.88807  -16.21862 -26.68581 1.000 36.57557  ? 95  THR A H    1 
ATOM   1452 H  HA   . THR A 1 115 ? 29.68876  -16.13597 -29.00507 1.000 41.20095  ? 95  THR A HA   1 
ATOM   1453 H  HB   . THR A 1 115 ? 31.38429  -17.50293 -29.78740 1.000 43.16639  ? 95  THR A HB   1 
ATOM   1454 H  HG1  . THR A 1 115 ? 32.71855  -18.42214 -28.33306 1.000 43.29903  ? 95  THR A HG1  1 
ATOM   1455 H  HG21 . THR A 1 115 ? 33.20080  -16.14958 -29.25639 1.000 50.33929  ? 95  THR A HG21 1 
ATOM   1456 H  HG22 . THR A 1 115 ? 31.93421  -15.21547 -29.38171 1.000 50.33929  ? 95  THR A HG22 1 
ATOM   1457 H  HG23 . THR A 1 115 ? 32.47398  -15.62648 -27.95615 1.000 50.33929  ? 95  THR A HG23 1 
ATOM   1458 N  N    . ARG A 1 116 ? 28.62176  -18.36468 -29.55325 1.000 34.67744  ? 96  ARG A N    1 
ATOM   1459 C  CA   . ARG A 1 116 ? 27.69444  -19.49119 -29.62013 1.000 33.39657  ? 96  ARG A CA   1 
ATOM   1460 C  C    . ARG A 1 116 ? 28.37899  -20.75624 -29.13715 1.000 34.64212  ? 96  ARG A C    1 
ATOM   1461 O  O    . ARG A 1 116 ? 27.77271  -21.55285 -28.40474 1.000 32.94052  ? 96  ARG A O    1 
ATOM   1462 C  CB   . ARG A 1 116 ? 27.14075  -19.67199 -31.04307 1.000 38.24026  ? 96  ARG A CB   1 
ATOM   1463 H  H    . ARG A 1 116 ? 28.77418  -17.96970 -30.30182 1.000 41.63669  ? 96  ARG A H    1 
ATOM   1464 H  HA   . ARG A 1 116 ? 26.93185  -19.30761 -29.04947 1.000 40.09965  ? 96  ARG A HA   1 
ATOM   1465 N  N    . LYS A 1 117 ? 29.66624  -20.92551 -29.48478 1.000 36.89381  ? 97  LYS A N    1 
ATOM   1466 C  CA   . LYS A 1 117 ? 30.41594  -22.10476 -29.06292 1.000 35.30924  ? 97  LYS A CA   1 
ATOM   1467 C  C    . LYS A 1 117 ? 30.64299  -22.11771 -27.55665 1.000 41.04882  ? 97  LYS A C    1 
ATOM   1468 O  O    . LYS A 1 117 ? 30.48129  -23.16089 -26.90688 1.000 39.12380  ? 97  LYS A O    1 
ATOM   1469 C  CB   . LYS A 1 117 ? 31.76644  -22.17270 -29.79910 1.000 38.38276  ? 97  LYS A CB   1 
ATOM   1470 H  H    . LYS A 1 117 ? 30.12042  -20.37231 -29.96153 1.000 44.29634  ? 97  LYS A H    1 
ATOM   1471 H  HA   . LYS A 1 117 ? 29.89878  -22.89064 -29.29921 1.000 42.39485  ? 97  LYS A HA   1 
ATOM   1472 N  N    . ARG A 1 118 ? 31.01545  -20.97488 -26.97276 1.000 37.30563  ? 98  ARG A N    1 
ATOM   1473 C  CA   . ARG A 1 118 ? 31.29191  -20.95894 -25.54019 1.000 35.52614  ? 98  ARG A CA   1 
ATOM   1474 C  C    . ARG A 1 118 ? 30.02966  -21.24566 -24.71970 1.000 34.24375  ? 98  ARG A C    1 
ATOM   1475 O  O    . ARG A 1 118 ? 30.08900  -21.89169 -23.66489 1.000 34.51313  ? 98  ARG A O    1 
ATOM   1476 C  CB   . ARG A 1 118 ? 31.86401  -19.60475 -25.13272 1.000 40.44524  ? 98  ARG A CB   1 
ATOM   1477 C  CG   . ARG A 1 118 ? 33.38078  -19.59963 -25.08148 1.000 51.91777  ? 98  ARG A CG   1 
ATOM   1478 C  CD   . ARG A 1 118 ? 33.86565  -18.37058 -24.38202 1.000 48.60208  ? 98  ARG A CD   1 
ATOM   1479 N  NE   . ARG A 1 118 ? 34.02223  -18.61478 -22.96035 1.000 52.68569  ? 98  ARG A NE   1 
ATOM   1480 C  CZ   . ARG A 1 118 ? 35.06911  -19.22009 -22.42076 1.000 58.15404  ? 98  ARG A CZ   1 
ATOM   1481 N  NH1  . ARG A 1 118 ? 36.07617  -19.65713 -23.16510 1.000 57.57290  ? 98  ARG A NH1  1 
ATOM   1482 N  NH2  . ARG A 1 118 ? 35.11141  -19.38212 -21.10238 1.000 57.15603  ? 98  ARG A NH2  1 
ATOM   1483 H  H    . ARG A 1 118 ? 31.11180  -20.21988 -27.37314 1.000 44.79051  ? 98  ARG A H    1 
ATOM   1484 H  HA   . ARG A 1 118 ? 31.94773  -21.64821 -25.35123 1.000 42.65513  ? 98  ARG A HA   1 
ATOM   1485 H  HB2  . ARG A 1 118 ? 31.58297  -18.93651 -25.77721 1.000 48.55805  ? 98  ARG A HB2  1 
ATOM   1486 H  HB3  . ARG A 1 118 ? 31.53287  -19.37472 -24.25049 1.000 48.55805  ? 98  ARG A HB3  1 
ATOM   1487 H  HG2  . ARG A 1 118 ? 33.69401  -20.37825 -24.59511 1.000 62.32509  ? 98  ARG A HG2  1 
ATOM   1488 H  HG3  . ARG A 1 118 ? 33.73829  -19.60576 -25.98318 1.000 62.32509  ? 98  ARG A HG3  1 
ATOM   1489 H  HD2  . ARG A 1 118 ? 34.72577  -18.10885 -24.74616 1.000 58.34626  ? 98  ARG A HD2  1 
ATOM   1490 H  HD3  . ARG A 1 118 ? 33.22257  -17.65446 -24.50255 1.000 58.34626  ? 98  ARG A HD3  1 
ATOM   1491 H  HE   . ARG A 1 118 ? 33.39532  -18.34957 -22.43476 1.000 63.24659  ? 98  ARG A HE   1 
ATOM   1492 H  HH11 . ARG A 1 118 ? 36.05849  -19.54989 -24.01821 1.000 69.11124  ? 98  ARG A HH11 1 
ATOM   1493 H  HH12 . ARG A 1 118 ? 36.74681  -20.04774 -22.79462 1.000 69.11124  ? 98  ARG A HH12 1 
ATOM   1494 H  HH21 . ARG A 1 118 ? 34.46490  -19.09560 -20.61297 1.000 68.61099  ? 98  ARG A HH21 1 
ATOM   1495 H  HH22 . ARG A 1 118 ? 35.78530  -19.77349 -20.73865 1.000 68.61099  ? 98  ARG A HH22 1 
ATOM   1496 N  N    . VAL A 1 119 ? 28.88123  -20.76118 -25.17866 1.000 33.95782  ? 99  VAL A N    1 
ATOM   1497 C  CA   . VAL A 1 119 ? 27.64833  -21.00071 -24.44543 1.000 28.38294  ? 99  VAL A CA   1 
ATOM   1498 C  C    . VAL A 1 119 ? 27.20272  -22.44307 -24.59625 1.000 31.50157  ? 99  VAL A C    1 
ATOM   1499 O  O    . VAL A 1 119 ? 26.88859  -23.11932 -23.60826 1.000 28.78291  ? 99  VAL A O    1 
ATOM   1500 C  CB   . VAL A 1 119 ? 26.55079  -20.03474 -24.90701 1.000 27.47738  ? 99  VAL A CB   1 
ATOM   1501 C  CG1  . VAL A 1 119 ? 25.23121  -20.42543 -24.24641 1.000 29.37924  ? 99  VAL A CG1  1 
ATOM   1502 C  CG2  . VAL A 1 119 ? 26.93280  -18.59041 -24.55762 1.000 32.81887  ? 99  VAL A CG2  1 
ATOM   1503 H  H    . VAL A 1 119 ? 28.79143  -20.29943 -25.89860 1.000 40.77314  ? 99  VAL A H    1 
ATOM   1504 H  HA   . VAL A 1 119 ? 27.82372  -20.83713 -23.50555 1.000 34.08329  ? 99  VAL A HA   1 
ATOM   1505 H  HB   . VAL A 1 119 ? 26.44558  -20.08579 -25.86993 1.000 32.99662  ? 99  VAL A HB   1 
ATOM   1506 H  HG11 . VAL A 1 119 ? 24.61703  -19.67660 -24.30063 1.000 35.27885  ? 99  VAL A HG11 1 
ATOM   1507 H  HG12 . VAL A 1 119 ? 24.86020  -21.19184 -24.71102 1.000 35.27885  ? 99  VAL A HG12 1 
ATOM   1508 H  HG13 . VAL A 1 119 ? 25.39744  -20.65031 -23.31759 1.000 35.27885  ? 99  VAL A HG13 1 
ATOM   1509 H  HG21 . VAL A 1 119 ? 26.21397  -17.99888 -24.83016 1.000 39.40640  ? 99  VAL A HG21 1 
ATOM   1510 H  HG22 . VAL A 1 119 ? 27.07133  -18.52325 -23.59992 1.000 39.40640  ? 99  VAL A HG22 1 
ATOM   1511 H  HG23 . VAL A 1 119 ? 27.74900  -18.35726 -25.02705 1.000 39.40640  ? 99  VAL A HG23 1 
ATOM   1512 N  N    . LYS A 1 120 ? 27.19595  -22.95060 -25.83373 1.000 33.25129  ? 100 LYS A N    1 
ATOM   1513 C  CA   . LYS A 1 120 ? 26.76536  -24.32410 -26.04462 1.000 31.87217  ? 100 LYS A CA   1 
ATOM   1514 C  C    . LYS A 1 120 ? 27.64241  -25.30674 -25.29595 1.000 31.82708  ? 100 LYS A C    1 
ATOM   1515 O  O    . LYS A 1 120 ? 27.14797  -26.33669 -24.82674 1.000 35.53745  ? 100 LYS A O    1 
ATOM   1516 C  CB   . LYS A 1 120 ? 26.76738  -24.65008 -27.53534 1.000 36.26615  ? 100 LYS A CB   1 
ATOM   1517 C  CG   . LYS A 1 120 ? 25.61884  -25.52355 -27.98610 1.000 58.09669  ? 100 LYS A CG   1 
ATOM   1518 C  CD   . LYS A 1 120 ? 25.96920  -27.00131 -27.89089 1.000 63.42326  ? 100 LYS A CD   1 
ATOM   1519 C  CE   . LYS A 1 120 ? 25.03336  -27.83878 -28.76147 1.000 58.48281  ? 100 LYS A CE   1 
ATOM   1520 N  NZ   . LYS A 1 120 ? 23.69693  -28.01428 -28.11534 1.000 65.59541  ? 100 LYS A NZ   1 
ATOM   1521 H  H    . LYS A 1 120 ? 27.43039  -22.52813 -26.54518 1.000 39.92531  ? 100 LYS A H    1 
ATOM   1522 H  HA   . LYS A 1 120 ? 25.85811  -24.41820 -25.71457 1.000 38.27037  ? 100 LYS A HA   1 
ATOM   1523 H  HB2  . LYS A 1 120 ? 26.71705  -23.81931 -28.03353 1.000 43.54314  ? 100 LYS A HB2  1 
ATOM   1524 H  HB3  . LYS A 1 120 ? 27.59115  -25.11559 -27.74889 1.000 43.54314  ? 100 LYS A HB3  1 
ATOM   1525 H  HG2  . LYS A 1 120 ? 24.84770  -25.35638 -27.42192 1.000 69.73979  ? 100 LYS A HG2  1 
ATOM   1526 H  HG3  . LYS A 1 120 ? 25.40427  -25.32030 -28.90999 1.000 69.73979  ? 100 LYS A HG3  1 
ATOM   1527 H  HD2  . LYS A 1 120 ? 26.87932  -27.13874 -28.19697 1.000 76.13167  ? 100 LYS A HD2  1 
ATOM   1528 H  HD3  . LYS A 1 120 ? 25.88032  -27.29661 -26.97122 1.000 76.13167  ? 100 LYS A HD3  1 
ATOM   1529 H  HE2  . LYS A 1 120 ? 24.90425  -27.39454 -29.61404 1.000 70.20313  ? 100 LYS A HE2  1 
ATOM   1530 H  HE3  . LYS A 1 120 ? 25.42294  -28.71621 -28.90020 1.000 70.20313  ? 100 LYS A HE3  1 
ATOM   1531 H  HZ1  . LYS A 1 120 ? 23.16677  -28.50018 -28.63968 1.000 78.73825  ? 100 LYS A HZ1  1 
ATOM   1532 H  HZ2  . LYS A 1 120 ? 23.78899  -28.42940 -27.33348 1.000 78.73825  ? 100 LYS A HZ2  1 
ATOM   1533 H  HZ3  . LYS A 1 120 ? 23.31857  -27.22049 -27.97811 1.000 78.73825  ? 100 LYS A HZ3  1 
ATOM   1534 N  N    . ASP A 1 121 ? 28.92649  -24.98529 -25.11946 1.000 31.48272  ? 101 ASP A N    1 
ATOM   1535 C  CA   . ASP A 1 121 ? 29.83995  -25.84647 -24.38750 1.000 32.92725  ? 101 ASP A CA   1 
ATOM   1536 C  C    . ASP A 1 121 ? 29.55401  -25.92681 -22.89141 1.000 33.13742  ? 101 ASP A C    1 
ATOM   1537 O  O    . ASP A 1 121 ? 30.10632  -26.81885 -22.22994 1.000 36.42362  ? 101 ASP A O    1 
ATOM   1538 C  CB   . ASP A 1 121 ? 31.28343  -25.38269 -24.58111 1.000 35.22488  ? 101 ASP A CB   1 
ATOM   1539 C  CG   . ASP A 1 121 ? 31.84173  -25.70684 -25.97208 1.000 48.77200  ? 101 ASP A CG   1 
ATOM   1540 O  OD1  . ASP A 1 121 ? 31.22573  -26.48166 -26.73462 1.000 47.34909  ? 101 ASP A OD1  1 
ATOM   1541 O  OD2  . ASP A 1 121 ? 32.89483  -25.14330 -26.30665 1.000 46.41643  ? 101 ASP A OD2  1 
ATOM   1542 H  H    . ASP A 1 121 ? 29.29134  -24.26625 -25.41858 1.000 37.80302  ? 101 ASP A H    1 
ATOM   1543 H  HA   . ASP A 1 121 ? 29.74408  -26.73825 -24.75687 1.000 39.53646  ? 101 ASP A HA   1 
ATOM   1544 H  HB2  . ASP A 1 121 ? 31.32332  -24.42101 -24.46081 1.000 42.29362  ? 101 ASP A HB2  1 
ATOM   1545 H  HB3  . ASP A 1 121 ? 31.84564  -25.82278 -23.92450 1.000 42.29362  ? 101 ASP A HB3  1 
ATOM   1546 N  N    . LYS A 1 122 ? 28.70832  -25.04141 -22.34973 1.000 33.20681  ? 102 LYS A N    1 
ATOM   1547 C  CA   . LYS A 1 122 ? 28.33220  -25.08191 -20.94515 1.000 31.46085  ? 102 LYS A CA   1 
ATOM   1548 C  C    . LYS A 1 122 ? 27.26534  -26.13068 -20.65763 1.000 31.40418  ? 102 LYS A C    1 
ATOM   1549 O  O    . LYS A 1 122 ? 26.92298  -26.35156 -19.48201 1.000 28.94174  ? 102 LYS A O    1 
ATOM   1550 C  CB   . LYS A 1 122 ? 27.84014  -23.69138 -20.51197 1.000 31.33590  ? 102 LYS A CB   1 
ATOM   1551 C  CG   . LYS A 1 122 ? 28.95915  -22.72717 -20.02529 1.000 41.28804  ? 102 LYS A CG   1 
ATOM   1552 C  CD   . LYS A 1 122 ? 28.56898  -21.95630 -18.71941 1.000 57.64411  ? 102 LYS A CD   1 
ATOM   1553 C  CE   . LYS A 1 122 ? 29.14448  -22.60387 -17.40756 1.000 66.02462  ? 102 LYS A CE   1 
ATOM   1554 N  NZ   . LYS A 1 122 ? 28.61367  -22.07137 -16.00665 1.000 41.87141  ? 102 LYS A NZ   1 
ATOM   1555 H  H    . LYS A 1 122 ? 28.33693  -24.40066 -22.78690 1.000 39.87194  ? 102 LYS A H    1 
ATOM   1556 H  HA   . LYS A 1 122 ? 29.10764  -25.30365 -20.40623 1.000 37.77678  ? 102 LYS A HA   1 
ATOM   1557 H  HB2  . LYS A 1 122 ? 27.40088  -23.27095 -21.26774 1.000 37.62685  ? 102 LYS A HB2  1 
ATOM   1558 H  HB3  . LYS A 1 122 ? 27.21126  -23.80099 -19.78164 1.000 37.62685  ? 102 LYS A HB3  1 
ATOM   1559 H  HG2  . LYS A 1 122 ? 29.76145  -23.24049 -19.84167 1.000 49.56941  ? 102 LYS A HG2  1 
ATOM   1560 H  HG3  . LYS A 1 122 ? 29.13587  -22.07196 -20.71838 1.000 49.56941  ? 102 LYS A HG3  1 
ATOM   1561 H  HD2  . LYS A 1 122 ? 28.91135  -21.05054 -18.77663 1.000 69.19670  ? 102 LYS A HD2  1 
ATOM   1562 H  HD3  . LYS A 1 122 ? 27.60219  -21.94126 -18.64199 1.000 69.19670  ? 102 LYS A HD3  1 
ATOM   1563 H  HE2  . LYS A 1 122 ? 28.94459  -23.55264 -17.43527 1.000 79.25331  ? 102 LYS A HE2  1 
ATOM   1564 H  HE3  . LYS A 1 122 ? 30.10478  -22.46699 -17.40833 1.000 79.25331  ? 102 LYS A HE3  1 
ATOM   1565 H  HZ1  . LYS A 1 122 ? 28.20295  -21.28916 -16.11413 1.000 50.26945  ? 102 LYS A HZ1  1 
ATOM   1566 H  HZ2  . LYS A 1 122 ? 28.03854  -22.65404 -15.65762 1.000 50.26945  ? 102 LYS A HZ2  1 
ATOM   1567 H  HZ3  . LYS A 1 122 ? 29.29465  -21.96507 -15.44356 1.000 50.26945  ? 102 LYS A HZ3  1 
ATOM   1568 N  N    . GLU A 1 123 ? 26.73145  -26.77476 -21.69516 1.000 30.08754  ? 103 GLU A N    1 
ATOM   1569 C  CA   . GLU A 1 123 ? 25.58398  -27.66746 -21.51724 1.000 28.72525  ? 103 GLU A CA   1 
ATOM   1570 C  C    . GLU A 1 123 ? 25.80972  -28.73242 -20.43717 1.000 28.23303  ? 103 GLU A C    1 
ATOM   1571 O  O    . GLU A 1 123 ? 24.96869  -28.91464 -19.54511 1.000 28.43692  ? 103 GLU A O    1 
ATOM   1572 C  CB   . GLU A 1 123 ? 25.23254  -28.33823 -22.85225 1.000 32.79647  ? 103 GLU A CB   1 
ATOM   1573 C  CG   . GLU A 1 123 ? 24.06015  -29.28480 -22.73405 1.000 31.68896  ? 103 GLU A CG   1 
ATOM   1574 C  CD   . GLU A 1 123 ? 23.42163  -29.61866 -24.07970 1.000 48.77171  ? 103 GLU A CD   1 
ATOM   1575 O  OE1  . GLU A 1 123 ? 23.78344  -28.99010 -25.10405 1.000 54.49075  ? 103 GLU A OE1  1 
ATOM   1576 O  OE2  . GLU A 1 123 ? 22.50990  -30.47135 -24.09014 1.000 54.79403  ? 103 GLU A OE2  1 
ATOM   1577 H  H    . GLU A 1 123 ? 27.01105  -26.71397 -22.50617 1.000 36.12881  ? 103 GLU A H    1 
ATOM   1578 H  HA   . GLU A 1 123 ? 24.83699  -27.12137 -21.22623 1.000 34.49406  ? 103 GLU A HA   1 
ATOM   1579 H  HB2  . GLU A 1 123 ? 25.00285  -27.65346 -23.49972 1.000 39.37953  ? 103 GLU A HB2  1 
ATOM   1580 H  HB3  . GLU A 1 123 ? 25.99890  -28.84511 -23.16319 1.000 39.37953  ? 103 GLU A HB3  1 
ATOM   1581 H  HG2  . GLU A 1 123 ? 24.36455  -30.11444 -22.33413 1.000 38.05052  ? 103 GLU A HG2  1 
ATOM   1582 H  HG3  . GLU A 1 123 ? 23.38107  -28.87640 -22.17462 1.000 38.05052  ? 103 GLU A HG3  1 
ATOM   1583 N  N    . ALA A 1 124 ? 26.93490  -29.44315 -20.48601 1.000 29.80146  ? 104 ALA A N    1 
ATOM   1584 C  CA   . ALA A 1 124 ? 27.16520  -30.51357 -19.51504 1.000 30.45366  ? 104 ALA A CA   1 
ATOM   1585 C  C    . ALA A 1 124 ? 27.18114  -29.98627 -18.08061 1.000 29.87722  ? 104 ALA A C    1 
ATOM   1586 O  O    . ALA A 1 124 ? 26.61240  -30.60668 -17.16580 1.000 30.04651  ? 104 ALA A O    1 
ATOM   1587 C  CB   . ALA A 1 124 ? 28.48716  -31.21840 -19.80818 1.000 31.24814  ? 104 ALA A CB   1 
ATOM   1588 H  H    . ALA A 1 124 ? 27.56760  -29.32993 -21.05739 1.000 35.78552  ? 104 ALA A H    1 
ATOM   1589 H  HA   . ALA A 1 124 ? 26.44063  -31.15269 -19.60112 1.000 36.56816  ? 104 ALA A HA   1 
ATOM   1590 H  HB1  . ALA A 1 124 ? 28.62072  -31.92334 -19.15541 1.000 37.52153  ? 104 ALA A HB1  1 
ATOM   1591 H  HB2  . ALA A 1 124 ? 28.45234  -31.59641 -20.70082 1.000 37.52153  ? 104 ALA A HB2  1 
ATOM   1592 H  HB3  . ALA A 1 124 ? 29.20885  -30.57287 -19.75025 1.000 37.52153  ? 104 ALA A HB3  1 
ATOM   1593 N  N    . SER A 1 125 ? 27.81893  -28.83684 -17.86359 1.000 27.66473  ? 105 SER A N    1 
ATOM   1594 C  CA   . SER A 1 125 ? 27.92224  -28.32531 -16.50655 1.000 28.01468  ? 105 SER A CA   1 
ATOM   1595 C  C    . SER A 1 125 ? 26.58006  -27.81697 -16.00214 1.000 26.22622  ? 105 SER A C    1 
ATOM   1596 O  O    . SER A 1 125 ? 26.25609  -28.00243 -14.81885 1.000 26.47610  ? 105 SER A O    1 
ATOM   1597 C  CB   . SER A 1 125 ? 28.99152  -27.23850 -16.43981 1.000 34.99479  ? 105 SER A CB   1 
ATOM   1598 O  OG   . SER A 1 125 ? 28.69245  -26.12823 -17.23562 1.000 36.35412  ? 105 SER A OG   1 
ATOM   1599 H  H    . SER A 1 125 ? 28.18867  -28.35039 -18.46877 1.000 33.22144  ? 105 SER A H    1 
ATOM   1600 H  HA   . SER A 1 125 ? 28.19880  -29.04395 -15.91665 1.000 33.64137  ? 105 SER A HA   1 
ATOM   1601 H  HB2  . SER A 1 125 ? 29.07265  -26.94362 -15.51928 1.000 42.01751  ? 105 SER A HB2  1 
ATOM   1602 H  HB3  . SER A 1 125 ? 29.83225  -27.61585 -16.74261 1.000 42.01751  ? 105 SER A HB3  1 
ATOM   1603 H  HG   . SER A 1 125 ? 28.61877  -26.36209 -18.03903 1.000 43.64870  ? 105 SER A HG   1 
ATOM   1604 N  N    . ILE A 1 126 ? 25.79287  -27.16607 -16.86940 1.000 26.43179  ? 106 ILE A N    1 
ATOM   1605 C  CA   . ILE A 1 126 ? 24.44785  -26.70952 -16.47870 1.000 25.85445  ? 106 ILE A CA   1 
ATOM   1606 C  C    . ILE A 1 126 ? 23.56536  -27.90040 -16.12464 1.000 24.33821  ? 106 ILE A C    1 
ATOM   1607 O  O    . ILE A 1 126 ? 22.82157  -27.87831 -15.13018 1.000 23.32901  ? 106 ILE A O    1 
ATOM   1608 C  CB   . ILE A 1 126 ? 23.81990  -25.86843 -17.60276 1.000 22.49772  ? 106 ILE A CB   1 
ATOM   1609 C  CG1  . ILE A 1 126 ? 24.64788  -24.62526 -17.83905 1.000 24.92223  ? 106 ILE A CG1  1 
ATOM   1610 C  CG2  . ILE A 1 126 ? 22.39774  -25.50210 -17.20333 1.000 24.27742  ? 106 ILE A CG2  1 
ATOM   1611 C  CD1  . ILE A 1 126 ? 24.24231  -23.85018 -19.03855 1.000 27.50913  ? 106 ILE A CD1  1 
ATOM   1612 H  H    . ILE A 1 126 ? 26.00890  -26.97749 -17.68018 1.000 31.74191  ? 106 ILE A H    1 
ATOM   1613 H  HA   . ILE A 1 126 ? 24.53162  -26.15023 -15.69062 1.000 31.04910  ? 106 ILE A HA   1 
ATOM   1614 H  HB   . ILE A 1 126 ? 23.80089  -26.37905 -18.42726 1.000 27.02102  ? 106 ILE A HB   1 
ATOM   1615 H  HG12 . ILE A 1 126 ? 24.56171  -24.04285 -17.06816 1.000 29.93044  ? 106 ILE A HG12 1 
ATOM   1616 H  HG13 . ILE A 1 126 ? 25.57479  -24.88628 -17.95569 1.000 29.93044  ? 106 ILE A HG13 1 
ATOM   1617 H  HG21 . ILE A 1 126 ? 22.08148  -24.78913 -17.78000 1.000 29.15667  ? 106 ILE A HG21 1 
ATOM   1618 H  HG22 . ILE A 1 126 ? 21.83097  -26.28312 -17.30172 1.000 29.15667  ? 106 ILE A HG22 1 
ATOM   1619 H  HG23 . ILE A 1 126 ? 22.39549  -25.20601 -16.27963 1.000 29.15667  ? 106 ILE A HG23 1 
ATOM   1620 H  HD11 . ILE A 1 126 ? 24.96287  -23.24927 -19.28475 1.000 33.03472  ? 106 ILE A HD11 1 
ATOM   1621 H  HD12 . ILE A 1 126 ? 24.06178  -24.46575 -19.76614 1.000 33.03472  ? 106 ILE A HD12 1 
ATOM   1622 H  HD13 . ILE A 1 126 ? 23.44348  -23.34090 -18.83024 1.000 33.03472  ? 106 ILE A HD13 1 
ATOM   1623 N  N    . ALA A 1 127 ? 23.60545  -28.94482 -16.95000 1.000 25.36146  ? 107 ALA A N    1 
ATOM   1624 C  CA   . ALA A 1 127 ? 22.81353  -30.14284 -16.69087 1.000 27.51889  ? 107 ALA A CA   1 
ATOM   1625 C  C    . ALA A 1 127 ? 23.17880  -30.76326 -15.33972 1.000 25.91870  ? 107 ALA A C    1 
ATOM   1626 O  O    . ALA A 1 127 ? 22.30205  -31.22542 -14.59588 1.000 26.25347  ? 107 ALA A O    1 
ATOM   1627 C  CB   . ALA A 1 127 ? 23.03650  -31.14829 -17.82516 1.000 29.97312  ? 107 ALA A CB   1 
ATOM   1628 H  H    . ALA A 1 127 ? 24.08164  -28.98520 -17.66499 1.000 30.45752  ? 107 ALA A H    1 
ATOM   1629 H  HA   . ALA A 1 127 ? 21.87226  -29.90996 -16.66495 1.000 33.04643  ? 107 ALA A HA   1 
ATOM   1630 H  HB1  . ALA A 1 127 ? 22.52233  -31.95015 -17.64200 1.000 35.99150  ? 107 ALA A HB1  1 
ATOM   1631 H  HB2  . ALA A 1 127 ? 22.74430  -30.75164 -18.66074 1.000 35.99150  ? 107 ALA A HB2  1 
ATOM   1632 H  HB3  . ALA A 1 127 ? 23.98076  -31.36481 -17.87416 1.000 35.99150  ? 107 ALA A HB3  1 
ATOM   1633 N  N    . ALA A 1 128 ? 24.47259  -30.83152 -15.03205 1.000 27.69856  ? 108 ALA A N    1 
ATOM   1634 C  CA   . ALA A 1 128 ? 24.88581  -31.37601 -13.74957 1.000 28.61356  ? 108 ALA A CA   1 
ATOM   1635 C  C    . ALA A 1 128 ? 24.29532  -30.57737 -12.59110 1.000 27.43667  ? 108 ALA A C    1 
ATOM   1636 O  O    . ALA A 1 128 ? 23.89082  -31.16430 -11.57273 1.000 27.60974  ? 108 ALA A O    1 
ATOM   1637 C  CB   . ALA A 1 128 ? 26.41440  -31.43236 -13.66843 1.000 29.85749  ? 108 ALA A CB   1 
ATOM   1638 H  H    . ALA A 1 128 ? 25.11653  -30.57354 -15.54037 1.000 33.26204  ? 108 ALA A H    1 
ATOM   1639 H  HA   . ALA A 1 128 ? 24.55710  -32.28533 -13.67216 1.000 34.36004  ? 108 ALA A HA   1 
ATOM   1640 H  HB1  . ALA A 1 128 ? 26.67195  -31.78090 -12.80062 1.000 35.85274  ? 108 ALA A HB1  1 
ATOM   1641 H  HB2  . ALA A 1 128 ? 26.74668  -32.01369 -14.37025 1.000 35.85274  ? 108 ALA A HB2  1 
ATOM   1642 H  HB3  . ALA A 1 128 ? 26.77000  -30.53736 -13.78423 1.000 35.85274  ? 108 ALA A HB3  1 
ATOM   1643 N  N    . LEU A 1 129 ? 24.27051  -29.24534 -12.71038 1.000 25.45132  ? 109 LEU A N    1 
ATOM   1644 C  CA   . LEU A 1 129 ? 23.67217  -28.41452 -11.66527 1.000 22.90731  ? 109 LEU A CA   1 
ATOM   1645 C  C    . LEU A 1 129 ? 22.18190  -28.66295 -11.53927 1.000 25.71246  ? 109 LEU A C    1 
ATOM   1646 O  O    . LEU A 1 129 ? 21.63918  -28.70490 -10.41916 1.000 25.20365  ? 109 LEU A O    1 
ATOM   1647 C  CB   . LEU A 1 129 ? 23.96417  -26.94142 -11.92071 1.000 24.45351  ? 109 LEU A CB   1 
ATOM   1648 C  CG   . LEU A 1 129 ? 25.38326  -26.47459 -11.57040 1.000 25.98195  ? 109 LEU A CG   1 
ATOM   1649 C  CD1  . LEU A 1 129 ? 25.61693  -25.11178 -12.20234 1.000 27.61532  ? 109 LEU A CD1  1 
ATOM   1650 C  CD2  . LEU A 1 129 ? 25.59270  -26.43519 -10.06240 1.000 30.82536  ? 109 LEU A CD2  1 
ATOM   1651 H  H    . LEU A 1 129 ? 24.58896  -28.80535 -13.37717 1.000 30.56534  ? 109 LEU A H    1 
ATOM   1652 H  HA   . LEU A 1 129 ? 24.08042  -28.64828 -10.81698 1.000 27.51254  ? 109 LEU A HA   1 
ATOM   1653 H  HB2  . LEU A 1 129 ? 23.82659  -26.76374 -12.86432 1.000 29.36798  ? 109 LEU A HB2  1 
ATOM   1654 H  HB3  . LEU A 1 129 ? 23.34737  -26.41314 -11.39026 1.000 29.36798  ? 109 LEU A HB3  1 
ATOM   1655 H  HG   . LEU A 1 129 ? 26.03715  -27.09994 -11.92006 1.000 31.20211  ? 109 LEU A HG   1 
ATOM   1656 H  HD11 . LEU A 1 129 ? 26.49975  -24.79573 -11.95407 1.000 33.16215  ? 109 LEU A HD11 1 
ATOM   1657 H  HD12 . LEU A 1 129 ? 25.55484  -25.19601 -13.16668 1.000 33.16215  ? 109 LEU A HD12 1 
ATOM   1658 H  HD13 . LEU A 1 129 ? 24.94181  -24.49430 -11.88009 1.000 33.16215  ? 109 LEU A HD13 1 
ATOM   1659 H  HD21 . LEU A 1 129 ? 26.46165  -26.04731 -9.87428  1.000 37.01420  ? 109 LEU A HD21 1 
ATOM   1660 H  HD22 . LEU A 1 129 ? 24.89498  -25.89415 -9.66069  1.000 37.01420  ? 109 LEU A HD22 1 
ATOM   1661 H  HD23 . LEU A 1 129 ? 25.55176  -27.33959 -9.71414  1.000 37.01420  ? 109 LEU A HD23 1 
ATOM   1662 N  N    . CYS A 1 130 ? 21.51160  -28.85304 -12.66522 1.000 23.42847  ? 110 CYS A N    1 
ATOM   1663 C  CA   . CYS A 1 130 ? 20.08689  -29.15932 -12.61659 1.000 23.65936  ? 110 CYS A CA   1 
ATOM   1664 C  C    . CYS A 1 130 ? 19.85771  -30.45638 -11.85520 1.000 26.77936  ? 110 CYS A C    1 
ATOM   1665 O  O    . CYS A 1 130 ? 18.95398  -30.56053 -11.00872 1.000 26.17683  ? 110 CYS A O    1 
ATOM   1666 C  CB   . CYS A 1 130 ? 19.53486  -29.29867 -14.05001 1.000 23.52877  ? 110 CYS A CB   1 
ATOM   1667 S  SG   . CYS A 1 130 ? 19.42016  -27.82659 -15.06014 1.000 24.92784  ? 110 CYS A SG   1 
ATOM   1668 H  H    . CYS A 1 130 ? 21.84802  -28.81190 -13.45562 1.000 28.13793  ? 110 CYS A H    1 
ATOM   1669 H  HA   . CYS A 1 130 ? 19.61620  -28.43677 -12.17244 1.000 28.41500  ? 110 CYS A HA   1 
ATOM   1670 H  HB2  . CYS A 1 130 ? 20.10896  -29.91789 -14.52737 1.000 28.25828  ? 110 CYS A HB2  1 
ATOM   1671 H  HB3  . CYS A 1 130 ? 18.63729  -29.66079 -13.98560 1.000 28.25828  ? 110 CYS A HB3  1 
ATOM   1672 H  HG   . CYS A 1 130 ? 20.50640  -27.32319 -15.14179 1.000 29.93716  ? 110 CYS A HG   1 
ATOM   1673 N  N    . ASP A 1 131 ? 20.66904  -31.46464 -12.14192 1.000 26.12605  ? 111 ASP A N    1 
ATOM   1674 C  CA   . ASP A 1 131 ? 20.46066  -32.73713 -11.47329 1.000 27.41100  ? 111 ASP A CA   1 
ATOM   1675 C  C    . ASP A 1 131 ? 20.81737  -32.66676 -9.99819  1.000 25.46535  ? 111 ASP A C    1 
ATOM   1676 O  O    . ASP A 1 131 ? 20.18323  -33.35909 -9.20318  1.000 28.46471  ? 111 ASP A O    1 
ATOM   1677 C  CB   . ASP A 1 131 ? 21.25321  -33.82460 -12.19353 1.000 31.91495  ? 111 ASP A CB   1 
ATOM   1678 C  CG   . ASP A 1 131 ? 20.54055  -34.30204 -13.47885 1.000 40.52668  ? 111 ASP A CG   1 
ATOM   1679 O  OD1  . ASP A 1 131 ? 19.30373  -34.55548 -13.47386 1.000 34.51766  ? 111 ASP A OD1  1 
ATOM   1680 O  OD2  . ASP A 1 131 ? 21.21790  -34.33357 -14.52990 1.000 39.67622  ? 111 ASP A OD2  1 
ATOM   1681 H  H    . ASP A 1 131 ? 21.32351  -31.43879 -12.69924 1.000 31.37502  ? 111 ASP A H    1 
ATOM   1682 H  HA   . ASP A 1 131 ? 19.52227  -32.97810 -11.52067 1.000 32.91696  ? 111 ASP A HA   1 
ATOM   1683 H  HB2  . ASP A 1 131 ? 22.12336  -33.47468 -12.44108 1.000 38.32170  ? 111 ASP A HB2  1 
ATOM   1684 H  HB3  . ASP A 1 131 ? 21.35796  -34.58728 -11.60341 1.000 38.32170  ? 111 ASP A HB3  1 
ATOM   1685 N  N    . THR A 1 132 ? 21.82276  -31.85916 -9.60972  1.000 26.33968  ? 112 THR A N    1 
ATOM   1686 C  CA   . THR A 1 132 ? 22.13995  -31.68415 -8.19191  1.000 28.77846  ? 112 THR A CA   1 
ATOM   1687 C  C    . THR A 1 132 ? 20.98126  -31.03367 -7.45114  1.000 25.92292  ? 112 THR A C    1 
ATOM   1688 O  O    . THR A 1 132 ? 20.63013  -31.45428 -6.33879  1.000 28.97505  ? 112 THR A O    1 
ATOM   1689 C  CB   . THR A 1 132 ? 23.40739  -30.83506 -8.03734  1.000 31.07342  ? 112 THR A CB   1 
ATOM   1690 O  OG1  . THR A 1 132 ? 24.53484  -31.56834 -8.56162  1.000 31.60202  ? 112 THR A OG1  1 
ATOM   1691 C  CG2  . THR A 1 132 ? 23.67605  -30.52865 -6.56709  1.000 34.69495  ? 112 THR A CG2  1 
ATOM   1692 H  H    . THR A 1 132 ? 22.32570  -31.41030 -10.14374 1.000 31.63138  ? 112 THR A H    1 
ATOM   1693 H  HA   . THR A 1 132 ? 22.30725  -32.55507 -7.79896  1.000 34.55791  ? 112 THR A HA   1 
ATOM   1694 H  HB   . THR A 1 132 ? 23.29372  -29.99872 -8.51537  1.000 37.31187  ? 112 THR A HB   1 
ATOM   1695 H  HG1  . THR A 1 132 ? 24.41577  -31.73442 -9.37638  1.000 37.94619  ? 112 THR A HG1  1 
ATOM   1696 H  HG21 . THR A 1 132 ? 24.58607  -30.21208 -6.45508  1.000 41.65771  ? 112 THR A HG21 1 
ATOM   1697 H  HG22 . THR A 1 132 ? 23.06395  -29.84461 -6.25353  1.000 41.65771  ? 112 THR A HG22 1 
ATOM   1698 H  HG23 . THR A 1 132 ? 23.55338  -31.32938 -6.03353  1.000 41.65771  ? 112 THR A HG23 1 
ATOM   1699 N  N    . LEU A 1 133 ? 20.39374  -30.01192 -8.05853  1.000 25.01544  ? 113 LEU A N    1 
ATOM   1700 C  CA   . LEU A 1 133 ? 19.28253  -29.29897 -7.42842  1.000 23.18800  ? 113 LEU A CA   1 
ATOM   1701 C  C    . LEU A 1 133 ? 18.06660  -30.20255 -7.29097  1.000 24.35269  ? 113 LEU A C    1 
ATOM   1702 O  O    . LEU A 1 133 ? 17.40737  -30.19222 -6.25107  1.000 26.06794  ? 113 LEU A O    1 
ATOM   1703 C  CB   . LEU A 1 133 ? 18.95033  -28.03429 -8.20019  1.000 23.78347  ? 113 LEU A CB   1 
ATOM   1704 C  CG   . LEU A 1 133 ? 20.00068  -26.92243 -8.03294  1.000 24.39153  ? 113 LEU A CG   1 
ATOM   1705 C  CD1  . LEU A 1 133 ? 19.75381  -25.85387 -9.09599  1.000 23.60852  ? 113 LEU A CD1  1 
ATOM   1706 C  CD2  . LEU A 1 133 ? 19.98044  -26.36357 -6.60178  1.000 27.69927  ? 113 LEU A CD2  1 
ATOM   1707 H  H    . LEU A 1 133 ? 20.61481  -29.70909 -8.83249  1.000 30.04229  ? 113 LEU A H    1 
ATOM   1708 H  HA   . LEU A 1 133 ? 19.55055  -29.02241 -6.53815  1.000 27.84936  ? 113 LEU A HA   1 
ATOM   1709 H  HB2  . LEU A 1 133 ? 18.89236  -28.25030 -9.14405  1.000 28.56393  ? 113 LEU A HB2  1 
ATOM   1710 H  HB3  . LEU A 1 133 ? 18.09953  -27.69062 -7.88565  1.000 28.56393  ? 113 LEU A HB3  1 
ATOM   1711 H  HG   . LEU A 1 133 ? 20.89750  -27.26829 -8.16327  1.000 29.29359  ? 113 LEU A HG   1 
ATOM   1712 H  HD11 . LEU A 1 133 ? 20.36625  -25.11593 -8.95018  1.000 28.35398  ? 113 LEU A HD11 1 
ATOM   1713 H  HD12 . LEU A 1 133 ? 19.90417  -26.24017 -9.97295  1.000 28.35398  ? 113 LEU A HD12 1 
ATOM   1714 H  HD13 . LEU A 1 133 ? 18.83789  -25.54269 -9.02423  1.000 28.35398  ? 113 LEU A HD13 1 
ATOM   1715 H  HD21 . LEU A 1 133 ? 20.48746  -25.53697 -6.57835  1.000 33.26289  ? 113 LEU A HD21 1 
ATOM   1716 H  HD22 . LEU A 1 133 ? 19.06130  -26.19533 -6.34143  1.000 33.26289  ? 113 LEU A HD22 1 
ATOM   1717 H  HD23 . LEU A 1 133 ? 20.38007  -27.01383 -6.00315  1.000 33.26289  ? 113 LEU A HD23 1 
ATOM   1718 N  N    . ILE A 1 134 ? 17.74688  -30.98335 -8.32671  1.000 25.78542  ? 114 ILE A N    1 
ATOM   1719 C  CA   . ILE A 1 134 ? 16.61174  -31.88959 -8.22926  1.000 26.37311  ? 114 ILE A CA   1 
ATOM   1720 C  C    . ILE A 1 134 ? 16.90318  -33.00705 -7.21881  1.000 28.25972  ? 114 ILE A C    1 
ATOM   1721 O  O    . ILE A 1 134 ? 16.00093  -33.46455 -6.50787  1.000 27.56559  ? 114 ILE A O    1 
ATOM   1722 C  CB   . ILE A 1 134 ? 16.26381  -32.45059 -9.61513  1.000 26.30237  ? 114 ILE A CB   1 
ATOM   1723 C  CG1  . ILE A 1 134 ? 15.72698  -31.32549 -10.48343 1.000 26.46643  ? 114 ILE A CG1  1 
ATOM   1724 C  CG2  . ILE A 1 134 ? 15.23443  -33.58997 -9.50097  1.000 24.69224  ? 114 ILE A CG2  1 
ATOM   1725 C  CD1  . ILE A 1 134 ? 15.54684  -31.69949 -11.93709 1.000 28.35624  ? 114 ILE A CD1  1 
ATOM   1726 H  H    . ILE A 1 134 ? 18.16416  -31.00409 -9.07841  1.000 30.96627  ? 114 ILE A H    1 
ATOM   1727 H  HA   . ILE A 1 134 ? 15.84384  -31.39242 -7.90671  1.000 31.67149  ? 114 ILE A HA   1 
ATOM   1728 H  HB   . ILE A 1 134 ? 17.06509  -32.81703 -10.02080 1.000 31.58661  ? 114 ILE A HB   1 
ATOM   1729 H  HG12 . ILE A 1 134 ? 14.86153  -31.05389 -10.13974 1.000 31.78348  ? 114 ILE A HG12 1 
ATOM   1730 H  HG13 . ILE A 1 134 ? 16.34752  -30.58091 -10.44558 1.000 31.78348  ? 114 ILE A HG13 1 
ATOM   1731 H  HG21 . ILE A 1 134 ? 14.88306  -33.78769 -10.38321 1.000 29.65445  ? 114 ILE A HG21 1 
ATOM   1732 H  HG22 . ILE A 1 134 ? 15.67150  -34.37499 -9.13543  1.000 29.65445  ? 114 ILE A HG22 1 
ATOM   1733 H  HG23 . ILE A 1 134 ? 14.51537  -33.30830 -8.91403  1.000 29.65445  ? 114 ILE A HG23 1 
ATOM   1734 H  HD11 . ILE A 1 134 ? 15.43703  -30.89002 -12.46016 1.000 34.05125  ? 114 ILE A HD11 1 
ATOM   1735 H  HD12 . ILE A 1 134 ? 16.33143  -32.18395 -12.23810 1.000 34.05125  ? 114 ILE A HD12 1 
ATOM   1736 H  HD13 . ILE A 1 134 ? 14.75916  -32.25886 -12.02398 1.000 34.05125  ? 114 ILE A HD13 1 
ATOM   1737 N  N    . ASP A 1 135 ? 18.15763  -33.49553 -7.16349  1.000 27.42405  ? 115 ASP A N    1 
ATOM   1738 C  CA   . ASP A 1 135 ? 18.53386  -34.46206 -6.14092  1.000 31.17484  ? 115 ASP A CA   1 
ATOM   1739 C  C    . ASP A 1 135 ? 18.25005  -33.95286 -4.72655  1.000 28.67337  ? 115 ASP A C    1 
ATOM   1740 O  O    . ASP A 1 135 ? 18.00710  -34.74312 -3.81686  1.000 31.22954  ? 115 ASP A O    1 
ATOM   1741 C  CB   . ASP A 1 135 ? 20.03059  -34.79272 -6.23188  1.000 31.39392  ? 115 ASP A CB   1 
ATOM   1742 C  CG   . ASP A 1 135 ? 20.37861  -35.78054 -7.31882  1.000 36.04147  ? 115 ASP A CG   1 
ATOM   1743 O  OD1  . ASP A 1 135 ? 19.49437  -36.35490 -7.97881  1.000 32.34158  ? 115 ASP A OD1  1 
ATOM   1744 O  OD2  . ASP A 1 135 ? 21.60724  -36.02286 -7.48021  1.000 37.45363  ? 115 ASP A OD2  1 
ATOM   1745 H  H    . ASP A 1 135 ? 18.79287  -33.28102 -7.70206  1.000 32.93262  ? 115 ASP A H    1 
ATOM   1746 H  HA   . ASP A 1 135 ? 18.01332  -35.26414 -6.30402  1.000 37.43357  ? 115 ASP A HA   1 
ATOM   1747 H  HB2  . ASP A 1 135 ? 20.51953  -33.97424 -6.41061  1.000 37.69646  ? 115 ASP A HB2  1 
ATOM   1748 H  HB3  . ASP A 1 135 ? 20.31706  -35.17242 -5.38651  1.000 37.69646  ? 115 ASP A HB3  1 
ATOM   1749 N  N    . ALA A 1 136 ? 18.29667  -32.65181 -4.51365  1.000 27.77599  ? 116 ALA A N    1 
ATOM   1750 C  CA   . ALA A 1 136 ? 18.09769  -32.11374 -3.18001  1.000 29.20374  ? 116 ALA A CA   1 
ATOM   1751 C  C    . ALA A 1 136 ? 16.64687  -32.15736 -2.72904  1.000 34.43036  ? 116 ALA A C    1 
ATOM   1752 O  O    . ALA A 1 136 ? 16.40329  -32.05106 -1.52499  1.000 36.93034  ? 116 ALA A O    1 
ATOM   1753 C  CB   . ALA A 1 136 ? 18.60473  -30.67166 -3.09104  1.000 29.95296  ? 116 ALA A CB   1 
ATOM   1754 H  H    . ALA A 1 136 ? 18.44122  -32.06004 -5.12071  1.000 33.35495  ? 116 ALA A H    1 
ATOM   1755 H  HA   . ALA A 1 136 ? 18.62158  -32.65229 -2.56649  1.000 35.06825  ? 116 ALA A HA   1 
ATOM   1756 H  HB1  . ALA A 1 136 ? 18.46466  -30.34273 -2.18933  1.000 35.96731  ? 116 ALA A HB1  1 
ATOM   1757 H  HB2  . ALA A 1 136 ? 19.55052  -30.65563 -3.30580  1.000 35.96731  ? 116 ALA A HB2  1 
ATOM   1758 H  HB3  . ALA A 1 136 ? 18.11272  -30.12437 -3.72294  1.000 35.96731  ? 116 ALA A HB3  1 
ATOM   1759 N  N    . VAL A 1 137 ? 15.68219  -32.30844 -3.63928  1.000 31.26604  ? 117 VAL A N    1 
ATOM   1760 C  CA   . VAL A 1 137 ? 14.27401  -32.31474 -3.25226  1.000 30.87474  ? 117 VAL A CA   1 
ATOM   1761 C  C    . VAL A 1 137 ? 13.52364  -33.56555 -3.66836  1.000 31.64713  ? 117 VAL A C    1 
ATOM   1762 O  O    . VAL A 1 137 ? 12.38518  -33.75933 -3.21457  1.000 29.80849  ? 117 VAL A O    1 
ATOM   1763 C  CB   . VAL A 1 137 ? 13.53863  -31.08179 -3.80665  1.000 31.93588  ? 117 VAL A CB   1 
ATOM   1764 C  CG1  . VAL A 1 137 ? 14.18434  -29.82013 -3.24959  1.000 35.79798  ? 117 VAL A CG1  1 
ATOM   1765 C  CG2  . VAL A 1 137 ? 13.52327  -31.10817 -5.32290  1.000 30.21690  ? 117 VAL A CG2  1 
ATOM   1766 H  H    . VAL A 1 137 ? 15.81946  -32.40839 -4.48235  1.000 37.54302  ? 117 VAL A H    1 
ATOM   1767 H  HA   . VAL A 1 137 ? 14.24639  -32.28231 -2.28320  1.000 37.07345  ? 117 VAL A HA   1 
ATOM   1768 H  HB   . VAL A 1 137 ? 12.61035  -31.08640 -3.52527  1.000 38.34682  ? 117 VAL A HB   1 
ATOM   1769 H  HG11 . VAL A 1 137 ? 13.68550  -29.04749 -3.55796  1.000 42.98134  ? 117 VAL A HG11 1 
ATOM   1770 H  HG12 . VAL A 1 137 ? 14.16860  -29.85878 -2.28049  1.000 42.98134  ? 117 VAL A HG12 1 
ATOM   1771 H  HG13 . VAL A 1 137 ? 15.10064  -29.76919 -3.56376  1.000 42.98134  ? 117 VAL A HG13 1 
ATOM   1772 H  HG21 . VAL A 1 137 ? 13.19886  -30.25467 -5.65033  1.000 36.28405  ? 117 VAL A HG21 1 
ATOM   1773 H  HG22 . VAL A 1 137 ? 14.42460  -31.26513 -5.64517  1.000 36.28405  ? 117 VAL A HG22 1 
ATOM   1774 H  HG23 . VAL A 1 137 ? 12.93675  -31.82117 -5.62042  1.000 36.28405  ? 117 VAL A HG23 1 
ATOM   1775 N  N    . CYS A 1 138 ? 14.09795  -34.40721 -4.52407  1.000 29.90909  ? 118 CYS A N    1 
ATOM   1776 C  CA   . CYS A 1 138 ? 13.30942  -35.45328 -5.15314  1.000 31.06688  ? 118 CYS A CA   1 
ATOM   1777 C  C    . CYS A 1 138 ? 12.82933  -36.49248 -4.13695  1.000 33.17773  ? 118 CYS A C    1 
ATOM   1778 O  O    . CYS A 1 138 ? 11.79779  -37.12077 -4.36257  1.000 32.75337  ? 118 CYS A O    1 
ATOM   1779 C  CB   . CYS A 1 138 ? 14.12605  -36.10422 -6.27730  1.000 31.15974  ? 118 CYS A CB   1 
ATOM   1780 S  SG   . CYS A 1 138 ? 15.67440  -36.90022 -5.78681  1.000 35.70318  ? 118 CYS A SG   1 
ATOM   1781 H  H    . CYS A 1 138 ? 14.92715  -34.39235 -4.75169  1.000 35.91467  ? 118 CYS A H    1 
ATOM   1782 H  HA   . CYS A 1 138 ? 12.51642  -35.06304 -5.55286  1.000 37.30402  ? 118 CYS A HA   1 
ATOM   1783 H  HB2  . CYS A 1 138 ? 13.57536  -36.78480 -6.69499  1.000 37.41545  ? 118 CYS A HB2  1 
ATOM   1784 H  HB3  . CYS A 1 138 ? 14.35107  -35.41680 -6.92362  1.000 37.41545  ? 118 CYS A HB3  1 
ATOM   1785 H  HG   . CYS A 1 138 ? 15.42914  -37.79894 -5.03040  1.000 42.86758  ? 118 CYS A HG   1 
ATOM   1786 N  N    . GLU A 1 139 ? 13.52175  -36.67034 -3.00764  1.000 35.30058  ? 119 GLU A N    1 
ATOM   1787 C  CA   . GLU A 1 139 ? 13.07089  -37.63102 -2.00456  1.000 36.34493  ? 119 GLU A CA   1 
ATOM   1788 C  C    . GLU A 1 139 ? 11.91673  -37.11417 -1.15244  1.000 33.25158  ? 119 GLU A C    1 
ATOM   1789 O  O    . GLU A 1 139 ? 11.27311  -37.92100 -0.46561  1.000 33.67085  ? 119 GLU A O    1 
ATOM   1790 C  CB   . GLU A 1 139 ? 14.23297  -38.01133 -1.07677  1.000 36.57143  ? 119 GLU A CB   1 
ATOM   1791 C  CG   . GLU A 1 139 ? 15.23981  -38.92427 -1.74654  1.000 43.20662  ? 119 GLU A CG   1 
ATOM   1792 C  CD   . GLU A 1 139 ? 16.52692  -39.06124 -0.95428  1.000 47.67102  ? 119 GLU A CD   1 
ATOM   1793 O  OE1  . GLU A 1 139 ? 17.14575  -38.02117 -0.62970  1.000 49.51565  ? 119 GLU A OE1  1 
ATOM   1794 O  OE2  . GLU A 1 139 ? 16.90090  -40.20478 -0.64132  1.000 50.75105  ? 119 GLU A OE2  1 
ATOM   1795 H  H    . GLU A 1 139 ? 14.24489  -36.25152 -2.80452  1.000 42.38445  ? 119 GLU A H    1 
ATOM   1796 H  HA   . GLU A 1 139 ? 12.77151  -38.42895 -2.46779  1.000 43.63768  ? 119 GLU A HA   1 
ATOM   1797 H  HB2  . GLU A 1 139 ? 14.69514  -37.20402 -0.80189  1.000 43.90948  ? 119 GLU A HB2  1 
ATOM   1798 H  HB3  . GLU A 1 139 ? 13.87934  -38.47203 -0.29986  1.000 43.90948  ? 119 GLU A HB3  1 
ATOM   1799 H  HG2  . GLU A 1 139 ? 14.85090  -39.80777 -1.84179  1.000 51.87170  ? 119 GLU A HG2  1 
ATOM   1800 H  HG3  . GLU A 1 139 ? 15.46183  -38.56367 -2.61922  1.000 51.87170  ? 119 GLU A HG3  1 
ATOM   1801 N  N    . ARG A 1 140 ? 11.64701  -35.81353 -1.19028  1.000 33.92290  ? 120 ARG A N    1 
ATOM   1802 C  CA   . ARG A 1 140 ? 10.71761  -35.19222 -0.25295  1.000 32.53102  ? 120 ARG A CA   1 
ATOM   1803 C  C    . ARG A 1 140 ? 9.26893   -35.25095 -0.72109  1.000 34.59659  ? 120 ARG A C    1 
ATOM   1804 O  O    . ARG A 1 140 ? 8.35714   -35.27275 0.11368   1.000 36.18448  ? 120 ARG A O    1 
ATOM   1805 C  CB   . ARG A 1 140 ? 11.08347  -33.72234 -0.03908  1.000 36.82652  ? 120 ARG A CB   1 
ATOM   1806 C  CG   . ARG A 1 140 ? 12.36450  -33.45277 0.71522   1.000 45.21689  ? 120 ARG A CG   1 
ATOM   1807 C  CD   . ARG A 1 140 ? 12.89348  -32.05874 0.35163   1.000 45.11696  ? 120 ARG A CD   1 
ATOM   1808 N  NE   . ARG A 1 140 ? 14.10364  -31.70928 1.08131   1.000 61.44134  ? 120 ARG A NE   1 
ATOM   1809 C  CZ   . ARG A 1 140 ? 14.44204  -30.47823 1.44241   1.000 74.90484  ? 120 ARG A CZ   1 
ATOM   1810 N  NH1  . ARG A 1 140 ? 13.72615  -29.42490 1.07666   1.000 60.18642  ? 120 ARG A NH1  1 
ATOM   1811 N  NH2  . ARG A 1 140 ? 15.53161  -30.29806 2.18406   1.000 83.13033  ? 120 ARG A NH2  1 
ATOM   1812 H  H    . ARG A 1 140 ? 11.99225  -35.26376 -1.75434  1.000 40.73124  ? 120 ARG A H    1 
ATOM   1813 H  HA   . ARG A 1 140 ? 10.79030  -35.66172 0.59274   1.000 39.06099  ? 120 ARG A HA   1 
ATOM   1814 H  HB2  . ARG A 1 140 ? 11.17191  -33.30376 -0.90964  1.000 44.21559  ? 120 ARG A HB2  1 
ATOM   1815 H  HB3  . ARG A 1 140 ? 10.36534  -33.30223 0.45961   1.000 44.21559  ? 120 ARG A HB3  1 
ATOM   1816 H  HG2  . ARG A 1 140 ? 12.19618  -33.48409 1.66999   1.000 54.28403  ? 120 ARG A HG2  1 
ATOM   1817 H  HG3  . ARG A 1 140 ? 13.03267  -34.11337 0.47428   1.000 54.28403  ? 120 ARG A HG3  1 
ATOM   1818 H  HD2  . ARG A 1 140 ? 13.09735  -32.03491 -0.59640  1.000 54.16411  ? 120 ARG A HD2  1 
ATOM   1819 H  HD3  . ARG A 1 140 ? 12.21509  -31.39805 0.56181   1.000 54.16411  ? 120 ARG A HD3  1 
ATOM   1820 H  HE   . ARG A 1 140 ? 14.63880  -32.34798 1.29407   1.000 73.75337  ? 120 ARG A HE   1 
ATOM   1821 H  HH11 . ARG A 1 140 ? 13.02272  -29.52993 0.59317   1.000 72.24747  ? 120 ARG A HH11 1 
ATOM   1822 H  HH12 . ARG A 1 140 ? 13.96495  -28.63622 1.32276   1.000 72.24747  ? 120 ARG A HH12 1 
ATOM   1823 H  HH21 . ARG A 1 140 ? 16.00589  -30.97453 2.42290   1.000 99.78016  ? 120 ARG A HH21 1 
ATOM   1824 H  HH22 . ARG A 1 140 ? 15.76171  -29.50512 2.42468   1.000 99.78016  ? 120 ARG A HH22 1 
ATOM   1825 N  N    . GLY A 1 141 ? 9.02639   -35.22946 -2.02710  1.000 31.20278  ? 121 GLY A N    1 
ATOM   1826 C  CA   . GLY A 1 141 ? 7.66526   -35.18629 -2.52838  1.000 31.24477  ? 121 GLY A CA   1 
ATOM   1827 C  C    . GLY A 1 141 ? 7.03203   -33.81289 -2.56193  1.000 30.05332  ? 121 GLY A C    1 
ATOM   1828 O  O    . GLY A 1 141 ? 5.88415   -33.69436 -3.01198  1.000 29.37475  ? 121 GLY A O    1 
ATOM   1829 H  H    . GLY A 1 141 ? 9.63240   -35.23923 -2.63722  1.000 37.46710  ? 121 GLY A H    1 
ATOM   1830 H  HA2  . GLY A 1 141 ? 7.65826   -35.53542 -3.43335  1.000 37.51748  ? 121 GLY A HA2  1 
ATOM   1831 H  HA3  . GLY A 1 141 ? 7.11154   -35.75169 -1.96748  1.000 37.51748  ? 121 GLY A HA3  1 
ATOM   1832 N  N    . GLU A 1 142 ? 7.73729   -32.78790 -2.09905  1.000 27.17674  ? 122 GLU A N    1 
ATOM   1833 C  CA   . GLU A 1 142 ? 7.26898   -31.41428 -2.11407  1.000 26.00967  ? 122 GLU A CA   1 
ATOM   1834 C  C    . GLU A 1 142 ? 8.47964   -30.51089 -2.16536  1.000 27.44941  ? 122 GLU A C    1 
ATOM   1835 O  O    . GLU A 1 142 ? 9.49880   -30.81845 -1.54122  1.000 29.47801  ? 122 GLU A O    1 
ATOM   1836 C  CB   . GLU A 1 142 ? 6.43618   -31.09213 -0.85327  1.000 28.19179  ? 122 GLU A CB   1 
ATOM   1837 C  CG   . GLU A 1 142 ? 5.56974   -29.81456 -0.99305  1.000 29.70497  ? 122 GLU A CG   1 
ATOM   1838 C  CD   . GLU A 1 142 ? 6.30651   -28.49612 -0.72132  1.000 27.56201  ? 122 GLU A CD   1 
ATOM   1839 O  OE1  . GLU A 1 142 ? 7.47009   -28.52336 -0.27009  1.000 34.14342  ? 122 GLU A OE1  1 
ATOM   1840 O  OE2  . GLU A 1 142 ? 5.70161   -27.40374 -0.95350  1.000 29.66754  ? 122 GLU A OE2  1 
ATOM   1841 H  H    . GLU A 1 142 ? 8.52248   -32.86817 -1.75753  1.000 32.63585  ? 122 GLU A H    1 
ATOM   1842 H  HA   . GLU A 1 142 ? 6.71600   -31.25834 -2.89561  1.000 31.23537  ? 122 GLU A HA   1 
ATOM   1843 H  HB2  . GLU A 1 142 ? 5.84087   -31.83651 -0.67325  1.000 33.85390  ? 122 GLU A HB2  1 
ATOM   1844 H  HB3  . GLU A 1 142 ? 7.03954   -30.96140 -0.10509  1.000 33.85390  ? 122 GLU A HB3  1 
ATOM   1845 H  HG2  . GLU A 1 142 ? 5.22682   -29.77368 -1.89949  1.000 35.66973  ? 122 GLU A HG2  1 
ATOM   1846 H  HG3  . GLU A 1 142 ? 4.83480   -29.87138 -0.36255  1.000 35.66973  ? 122 GLU A HG3  1 
ATOM   1847 N  N    . CYS A 1 143 ? 8.35613   -29.39376 -2.87698  1.000 24.89695  ? 123 CYS A N    1 
ATOM   1848 C  CA   . CYS A 1 143 ? 9.32301   -28.30777 -2.74184  1.000 27.34408  ? 123 CYS A CA   1 
ATOM   1849 C  C    . CYS A 1 143 ? 8.64546   -26.98595 -3.11102  1.000 26.51695  ? 123 CYS A C    1 
ATOM   1850 O  O    . CYS A 1 143 ? 7.50864   -26.93822 -3.59214  1.000 25.95742  ? 123 CYS A O    1 
ATOM   1851 C  CB   . CYS A 1 143 ? 10.57844  -28.52556 -3.60757  1.000 25.47666  ? 123 CYS A CB   1 
ATOM   1852 S  SG   . CYS A 1 143 ? 10.37367  -28.33065 -5.39661  1.000 27.56853  ? 123 CYS A SG   1 
ATOM   1853 H  H    . CYS A 1 143 ? 7.72521   -29.24140 -3.44119  1.000 29.90010  ? 123 CYS A H    1 
ATOM   1854 H  HA   . CYS A 1 143 ? 9.60223   -28.26841 -1.81374  1.000 32.83666  ? 123 CYS A HA   1 
ATOM   1855 H  HB2  . CYS A 1 143 ? 11.25152  -27.88576 -3.32737  1.000 30.59576  ? 123 CYS A HB2  1 
ATOM   1856 H  HB3  . CYS A 1 143 ? 10.89584  -29.42934 -3.45483  1.000 30.59576  ? 123 CYS A HB3  1 
ATOM   1857 H  HG   . CYS A 1 143 ? 11.40098  -28.62609 -5.94191  1.000 33.10600  ? 123 CYS A HG   1 
ATOM   1858 N  N    . ASP A 1 144 ? 9.36105   -25.88624 -2.88154  1.000 26.24946  ? 124 ASP A N    1 
ATOM   1859 C  CA   . ASP A 1 144 ? 8.97556   -24.58813 -3.40656  1.000 22.05141  ? 124 ASP A CA   1 
ATOM   1860 C  C    . ASP A 1 144 ? 9.74467   -24.44199 -4.70857  1.000 22.99597  ? 124 ASP A C    1 
ATOM   1861 O  O    . ASP A 1 144 ? 10.97744  -24.32490 -4.69638  1.000 24.30430  ? 124 ASP A O    1 
ATOM   1862 C  CB   . ASP A 1 144 ? 9.30032   -23.46883 -2.42930  1.000 22.71621  ? 124 ASP A CB   1 
ATOM   1863 C  CG   . ASP A 1 144 ? 8.82879   -22.10792 -2.92057  1.000 25.69193  ? 124 ASP A CG   1 
ATOM   1864 O  OD1  . ASP A 1 144 ? 8.66362   -21.87414 -4.14933  1.000 24.51109  ? 124 ASP A OD1  1 
ATOM   1865 O  OD2  . ASP A 1 144 ? 8.51696   -21.26272 -2.03604  1.000 34.72393  ? 124 ASP A OD2  1 
ATOM   1866 H  H    . ASP A 1 144 ? 10.08445  -25.87117 -2.41672  1.000 31.52311  ? 124 ASP A H    1 
ATOM   1867 H  HA   . ASP A 1 144 ? 8.01956   -24.54021 -3.56360  1.000 26.48546  ? 124 ASP A HA   1 
ATOM   1868 H  HB2  . ASP A 1 144 ? 8.86308   -23.65080 -1.58277  1.000 27.28321  ? 124 ASP A HB2  1 
ATOM   1869 H  HB3  . ASP A 1 144 ? 10.26128  -23.42673 -2.30405  1.000 27.28321  ? 124 ASP A HB3  1 
ATOM   1870 N  N    . PHE A 1 145 ? 9.04069   -24.54692 -5.83454  1.000 22.83009  ? 125 PHE A N    1 
ATOM   1871 C  CA   . PHE A 1 145 ? 9.72839   -24.54565 -7.12471  1.000 22.45115  ? 125 PHE A CA   1 
ATOM   1872 C  C    . PHE A 1 145 ? 10.57014  -23.28844 -7.31363  1.000 21.79453  ? 125 PHE A C    1 
ATOM   1873 O  O    . PHE A 1 145 ? 11.66395  -23.35219 -7.88908  1.000 21.60369  ? 125 PHE A O    1 
ATOM   1874 C  CB   . PHE A 1 145 ? 8.70735   -24.66555 -8.25362  1.000 20.00184  ? 125 PHE A CB   1 
ATOM   1875 C  CG   . PHE A 1 145 ? 9.29511   -25.01297 -9.59628  1.000 21.90599  ? 125 PHE A CG   1 
ATOM   1876 C  CD1  . PHE A 1 145 ? 9.43711   -26.33427 -9.97881  1.000 21.14506  ? 125 PHE A CD1  1 
ATOM   1877 C  CD2  . PHE A 1 145 ? 9.69303   -24.01304 -10.45250 1.000 21.47100  ? 125 PHE A CD2  1 
ATOM   1878 C  CE1  . PHE A 1 145 ? 9.98975   -26.65382 -11.19691 1.000 23.35961  ? 125 PHE A CE1  1 
ATOM   1879 C  CE2  . PHE A 1 145 ? 10.26266  -24.33187 -11.70105 1.000 20.10101  ? 125 PHE A CE2  1 
ATOM   1880 C  CZ   . PHE A 1 145 ? 10.38129  -25.64743 -12.05648 1.000 21.33325  ? 125 PHE A CZ   1 
ATOM   1881 H  H    . PHE A 1 145 ? 8.18482   -24.61840 -5.87914  1.000 27.41987  ? 125 PHE A H    1 
ATOM   1882 H  HA   . PHE A 1 145 ? 10.32148  -25.31224 -7.16319  1.000 26.96514  ? 125 PHE A HA   1 
ATOM   1883 H  HB2  . PHE A 1 145 ? 8.07275   -25.36200 -8.02311  1.000 24.02597  ? 125 PHE A HB2  1 
ATOM   1884 H  HB3  . PHE A 1 145 ? 8.24846   -23.81599 -8.34623  1.000 24.02597  ? 125 PHE A HB3  1 
ATOM   1885 H  HD1  . PHE A 1 145 ? 9.15654   -27.01242 -9.40758  1.000 25.39783  ? 125 PHE A HD1  1 
ATOM   1886 H  HD2  . PHE A 1 145 ? 9.58566   -23.12266 -10.20633 1.000 25.78897  ? 125 PHE A HD2  1 
ATOM   1887 H  HE1  . PHE A 1 145 ? 10.09924  -27.54464 -11.44053 1.000 28.05529  ? 125 PHE A HE1  1 
ATOM   1888 H  HE2  . PHE A 1 145 ? 10.55310  -23.65926 -12.27388 1.000 24.14498  ? 125 PHE A HE2  1 
ATOM   1889 H  HZ   . PHE A 1 145 ? 10.73099  -25.86703 -12.88978 1.000 25.62366  ? 125 PHE A HZ   1 
ATOM   1890 N  N    . VAL A 1 146 ? 10.10824  -22.14874 -6.81712  1.000 22.54353  ? 126 VAL A N    1 
ATOM   1891 C  CA   . VAL A 1 146 ? 10.89220  -20.91991 -6.93454  1.000 22.69436  ? 126 VAL A CA   1 
ATOM   1892 C  C    . VAL A 1 146 ? 12.17417  -21.01398 -6.11371  1.000 23.19500  ? 126 VAL A C    1 
ATOM   1893 O  O    . VAL A 1 146 ? 13.27688  -20.85561 -6.63603  1.000 23.99120  ? 126 VAL A O    1 
ATOM   1894 C  CB   . VAL A 1 146 ? 10.05840  -19.70749 -6.50174  1.000 21.78595  ? 126 VAL A CB   1 
ATOM   1895 C  CG1  . VAL A 1 146 ? 10.95242  -18.45481 -6.39479  1.000 26.85931  ? 126 VAL A CG1  1 
ATOM   1896 C  CG2  . VAL A 1 146 ? 8.86367   -19.47398 -7.46609  1.000 23.40276  ? 126 VAL A CG2  1 
ATOM   1897 H  H    . VAL A 1 146 ? 9.35488   -22.05726 -6.41255  1.000 27.07600  ? 126 VAL A H    1 
ATOM   1898 H  HA   . VAL A 1 146 ? 11.13866  -20.81054 -7.86631  1.000 27.25699  ? 126 VAL A HA   1 
ATOM   1899 H  HB   . VAL A 1 146 ? 9.68309   -19.88225 -5.62452  1.000 26.16690  ? 126 VAL A HB   1 
ATOM   1900 H  HG11 . VAL A 1 146 ? 10.38845  -17.66638 -6.35990  1.000 32.25494  ? 126 VAL A HG11 1 
ATOM   1901 H  HG12 . VAL A 1 146 ? 11.48612  -18.51575 -5.58711  1.000 32.25494  ? 126 VAL A HG12 1 
ATOM   1902 H  HG13 . VAL A 1 146 ? 11.53172  -18.41301 -7.17168  1.000 32.25494  ? 126 VAL A HG13 1 
ATOM   1903 H  HG21 . VAL A 1 146 ? 8.36233   -18.69967 -7.16607  1.000 28.10707  ? 126 VAL A HG21 1 
ATOM   1904 H  HG22 . VAL A 1 146 ? 9.20538   -19.32043 -8.36083  1.000 28.10707  ? 126 VAL A HG22 1 
ATOM   1905 H  HG23 . VAL A 1 146 ? 8.29446   -20.25939 -7.45966  1.000 28.10707  ? 126 VAL A HG23 1 
ATOM   1906 N  N    . ARG A 1 147 ? 12.04555  -21.28849 -4.81218  1.000 23.19235  ? 127 ARG A N    1 
ATOM   1907 C  CA   . ARG A 1 147 ? 13.19552  -21.27800 -3.90496  1.000 22.75837  ? 127 ARG A CA   1 
ATOM   1908 C  C    . ARG A 1 147 ? 14.19638  -22.38020 -4.21875  1.000 24.13634  ? 127 ARG A C    1 
ATOM   1909 O  O    . ARG A 1 147 ? 15.41975  -22.17965 -4.07678  1.000 26.63080  ? 127 ARG A O    1 
ATOM   1910 C  CB   . ARG A 1 147 ? 12.69492  -21.41268 -2.45992  1.000 25.09881  ? 127 ARG A CB   1 
ATOM   1911 C  CG   . ARG A 1 147 ? 13.78169  -21.21480 -1.37969  1.000 30.54473  ? 127 ARG A CG   1 
ATOM   1912 C  CD   . ARG A 1 147 ? 13.31638  -21.68170 -0.00237  1.000 30.90012  ? 127 ARG A CD   1 
ATOM   1913 N  NE   . ARG A 1 147 ? 12.91189  -23.06707 -0.08902  1.000 33.61918  ? 127 ARG A NE   1 
ATOM   1914 C  CZ   . ARG A 1 147 ? 11.87217  -23.60368 0.52352   1.000 35.15374  ? 127 ARG A CZ   1 
ATOM   1915 N  NH1  . ARG A 1 147 ? 11.15254  -22.91475 1.40019   1.000 41.29208  ? 127 ARG A NH1  1 
ATOM   1916 N  NH2  . ARG A 1 147 ? 11.54822  -24.85591 0.24852   1.000 34.18534  ? 127 ARG A NH2  1 
ATOM   1917 H  H    . ARG A 1 147 ? 11.30164  -21.48450 -4.42777  1.000 27.85458  ? 127 ARG A H    1 
ATOM   1918 H  HA   . ARG A 1 147 ? 13.66076  -20.43321 -4.00884  1.000 27.33380  ? 127 ARG A HA   1 
ATOM   1919 H  HB2  . ARG A 1 147 ? 12.00742  -20.74538 -2.30844  1.000 30.14234  ? 127 ARG A HB2  1 
ATOM   1920 H  HB3  . ARG A 1 147 ? 12.32553  -22.30198 -2.34332  1.000 30.14234  ? 127 ARG A HB3  1 
ATOM   1921 H  HG2  . ARG A 1 147 ? 14.56910  -21.72676 -1.62211  1.000 36.67744  ? 127 ARG A HG2  1 
ATOM   1922 H  HG3  . ARG A 1 147 ? 14.00403  -20.27251 -1.32003  1.000 36.67744  ? 127 ARG A HG3  1 
ATOM   1923 H  HD2  . ARG A 1 147 ? 14.04248  -21.60400 0.63610   1.000 37.10391  ? 127 ARG A HD2  1 
ATOM   1924 H  HD3  . ARG A 1 147 ? 12.55976  -21.14940 0.28929   1.000 37.10391  ? 127 ARG A HD3  1 
ATOM   1925 H  HE   . ARG A 1 147 ? 13.38911  -23.58603 -0.58151  1.000 40.36678  ? 127 ARG A HE   1 
ATOM   1926 H  HH11 . ARG A 1 147 ? 11.35956  -22.09976 1.58058   1.000 49.57425  ? 127 ARG A HH11 1 
ATOM   1927 H  HH12 . ARG A 1 147 ? 10.47916  -23.28327 1.78794   1.000 49.57425  ? 127 ARG A HH12 1 
ATOM   1928 H  HH21 . ARG A 1 147 ? 12.01160  -25.30503 -0.31997  1.000 41.04616  ? 127 ARG A HH21 1 
ATOM   1929 H  HH22 . ARG A 1 147 ? 10.87416  -25.22119 0.63816   1.000 41.04616  ? 127 ARG A HH22 1 
ATOM   1930 N  N    . ASP A 1 148 ? 13.70958  -23.55532 -4.62999  1.000 23.69360  ? 128 ASP A N    1 
ATOM   1931 C  CA   . ASP A 1 148 ? 14.54867  -24.74385 -4.67329  1.000 23.10634  ? 128 ASP A CA   1 
ATOM   1932 C  C    . ASP A 1 148 ? 15.05425  -25.10433 -6.06315  1.000 23.87041  ? 128 ASP A C    1 
ATOM   1933 O  O    . ASP A 1 148 ? 16.01798  -25.87493 -6.16137  1.000 24.18597  ? 128 ASP A O    1 
ATOM   1934 C  CB   . ASP A 1 148 ? 13.78687  -25.92288 -4.08688  1.000 25.17144  ? 128 ASP A CB   1 
ATOM   1935 C  CG   . ASP A 1 148 ? 13.38654  -25.67833 -2.63504  1.000 32.31374  ? 128 ASP A CG   1 
ATOM   1936 O  OD1  . ASP A 1 148 ? 14.15347  -24.98447 -1.90125  1.000 31.99036  ? 128 ASP A OD1  1 
ATOM   1937 O  OD2  . ASP A 1 148 ? 12.34031  -26.21904 -2.22204  1.000 28.83483  ? 128 ASP A OD2  1 
ATOM   1938 H  H    . ASP A 1 148 ? 12.89896  -23.68375 -4.88691  1.000 28.45609  ? 128 ASP A H    1 
ATOM   1939 H  HA   . ASP A 1 148 ? 15.33635  -24.58736 -4.12927  1.000 27.75137  ? 128 ASP A HA   1 
ATOM   1940 H  HB2  . ASP A 1 148 ? 12.97921  -26.06982 -4.60359  1.000 30.22949  ? 128 ASP A HB2  1 
ATOM   1941 H  HB3  . ASP A 1 148 ? 14.34873  -26.71299 -4.11762  1.000 30.22949  ? 128 ASP A HB3  1 
ATOM   1942 N  N    . LEU A 1 149 ? 14.41671  -24.59816 -7.12415  1.000 21.60648  ? 129 LEU A N    1 
ATOM   1943 C  CA   . LEU A 1 149 ? 14.82156  -24.95026 -8.48365  1.000 22.04948  ? 129 LEU A CA   1 
ATOM   1944 C  C    . LEU A 1 149 ? 14.99524  -23.72046 -9.35885  1.000 22.19309  ? 129 LEU A C    1 
ATOM   1945 O  O    . LEU A 1 149 ? 16.05222  -23.54566 -9.96904  1.000 22.10962  ? 129 LEU A O    1 
ATOM   1946 C  CB   . LEU A 1 149 ? 13.78796  -25.89342 -9.12491  1.000 22.75780  ? 129 LEU A CB   1 
ATOM   1947 C  CG   . LEU A 1 149 ? 13.71669  -27.24847 -8.45662  1.000 24.58512  ? 129 LEU A CG   1 
ATOM   1948 C  CD1  . LEU A 1 149 ? 12.56926  -28.08682 -8.94433  1.000 25.53507  ? 129 LEU A CD1  1 
ATOM   1949 C  CD2  . LEU A 1 149 ? 14.99970  -28.11860 -8.61875  1.000 28.16754  ? 129 LEU A CD2  1 
ATOM   1950 H  H    . LEU A 1 149 ? 13.75255  -24.05354 -7.08078  1.000 25.95154  ? 129 LEU A H    1 
ATOM   1951 H  HA   . LEU A 1 149 ? 15.67735  -25.40404 -8.43248  1.000 26.48313  ? 129 LEU A HA   1 
ATOM   1952 H  HB2  . LEU A 1 149 ? 12.91074  -25.48397 -9.06377  1.000 27.33312  ? 129 LEU A HB2  1 
ATOM   1953 H  HB3  . LEU A 1 149 ? 14.02550  -26.03156 -10.05518 1.000 27.33312  ? 129 LEU A HB3  1 
ATOM   1954 H  HG   . LEU A 1 149 ? 13.60217  -27.02239 -7.52031  1.000 29.52591  ? 129 LEU A HG   1 
ATOM   1955 H  HD11 . LEU A 1 149 ? 12.54574  -28.91451 -8.43908  1.000 30.66584  ? 129 LEU A HD11 1 
ATOM   1956 H  HD12 . LEU A 1 149 ? 11.74240  -27.59652 -8.81467  1.000 30.66584  ? 129 LEU A HD12 1 
ATOM   1957 H  HD13 . LEU A 1 149 ? 12.69609  -28.27809 -9.88679  1.000 30.66584  ? 129 LEU A HD13 1 
ATOM   1958 H  HD21 . LEU A 1 149 ? 14.81380  -29.01708 -8.30398  1.000 33.82481  ? 129 LEU A HD21 1 
ATOM   1959 H  HD22 . LEU A 1 149 ? 15.24946  -28.14144 -9.55576  1.000 33.82481  ? 129 LEU A HD22 1 
ATOM   1960 H  HD23 . LEU A 1 149 ? 15.71569  -27.72617 -8.09505  1.000 33.82481  ? 129 LEU A HD23 1 
ATOM   1961 N  N    . ALA A 1 150 ? 14.00536  -22.83390 -9.40678  1.000 20.30756  ? 130 ALA A N    1 
ATOM   1962 C  CA   . ALA A 1 150 ? 14.03802  -21.74433 -10.39541 1.000 21.49335  ? 130 ALA A CA   1 
ATOM   1963 C  C    . ALA A 1 150 ? 15.05914  -20.66116 -10.05199 1.000 19.81903  ? 130 ALA A C    1 
ATOM   1964 O  O    . ALA A 1 150 ? 15.78828  -20.20716 -10.95762 1.000 20.56597  ? 130 ALA A O    1 
ATOM   1965 C  CB   . ALA A 1 150 ? 12.65621  -21.10035 -10.56578 1.000 20.35171  ? 130 ALA A CB   1 
ATOM   1966 H  H    . ALA A 1 150 ? 13.31578  -22.83465 -8.89290  1.000 24.39283  ? 130 ALA A H    1 
ATOM   1967 H  HA   . ALA A 1 150 ? 14.29597  -22.15070 -11.23756 1.000 25.81578  ? 130 ALA A HA   1 
ATOM   1968 H  HB1  . ALA A 1 150 ? 12.70653  -20.42344 -11.25871 1.000 24.44581  ? 130 ALA A HB1  1 
ATOM   1969 H  HB2  . ALA A 1 150 ? 12.01752  -21.78535 -10.81829 1.000 24.44581  ? 130 ALA A HB2  1 
ATOM   1970 H  HB3  . ALA A 1 150 ? 12.39115  -20.69455 -9.72557  1.000 24.44581  ? 130 ALA A HB3  1 
ATOM   1971 N  N    . ALA A 1 151 ? 15.15452  -20.25187 -8.79689  1.000 20.85667  ? 131 ALA A N    1 
ATOM   1972 C  CA   . ALA A 1 151 ? 16.14130  -19.23935 -8.44280  1.000 22.57549  ? 131 ALA A CA   1 
ATOM   1973 C  C    . ALA A 1 151 ? 17.55791  -19.80821 -8.34387  1.000 21.41370  ? 131 ALA A C    1 
ATOM   1974 O  O    . ALA A 1 151 ? 18.49648  -19.16467 -8.84274  1.000 21.85731  ? 131 ALA A O    1 
ATOM   1975 C  CB   . ALA A 1 151 ? 15.76555  -18.55225 -7.13330  1.000 24.44091  ? 131 ALA A CB   1 
ATOM   1976 H  H    . ALA A 1 151 ? 14.67127  -20.53730 -8.14527  1.000 25.05176  ? 131 ALA A H    1 
ATOM   1977 H  HA   . ALA A 1 151 ? 16.15026  -18.58544 -9.15919  1.000 27.11435  ? 131 ALA A HA   1 
ATOM   1978 H  HB1  . ALA A 1 151 ? 16.52752  -18.04453 -6.81310  1.000 29.35286  ? 131 ALA A HB1  1 
ATOM   1979 H  HB2  . ALA A 1 151 ? 15.01542  -17.95817 -7.29229  1.000 29.35286  ? 131 ALA A HB2  1 
ATOM   1980 H  HB3  . ALA A 1 151 ? 15.52041  -19.22741 -6.48141  1.000 29.35286  ? 131 ALA A HB3  1 
ATOM   1981 N  N    . PRO A 1 152 ? 17.76821  -21.00324 -7.79286  1.000 22.57931  ? 132 PRO A N    1 
ATOM   1982 C  CA   . PRO A 1 152 ? 19.15961  -21.44517 -7.59685  1.000 21.99043  ? 132 PRO A CA   1 
ATOM   1983 C  C    . PRO A 1 152 ? 19.86507  -21.84478 -8.87732  1.000 21.64304  ? 132 PRO A C    1 
ATOM   1984 O  O    . PRO A 1 152 ? 21.09149  -21.71141 -8.93981  1.000 21.91751  ? 132 PRO A O    1 
ATOM   1985 C  CB   . PRO A 1 152 ? 19.04335  -22.66164 -6.65917  1.000 23.01252  ? 132 PRO A CB   1 
ATOM   1986 C  CG   . PRO A 1 152 ? 17.71034  -22.61439 -6.11272  1.000 30.48796  ? 132 PRO A CG   1 
ATOM   1987 C  CD   . PRO A 1 152 ? 16.81867  -21.77189 -6.96833  1.000 22.92085  ? 132 PRO A CD   1 
ATOM   1988 H  HA   . PRO A 1 152 ? 19.64675  -20.73161 -7.15591  1.000 26.41228  ? 132 PRO A HA   1 
ATOM   1989 H  HB2  . PRO A 1 152 ? 19.17853  -23.47794 -7.16542  1.000 27.63878  ? 132 PRO A HB2  1 
ATOM   1990 H  HB3  . PRO A 1 152 ? 19.70633  -22.59480 -5.95426  1.000 27.63878  ? 132 PRO A HB3  1 
ATOM   1991 H  HG2  . PRO A 1 152 ? 17.36275  -23.51906 -6.07211  1.000 36.60931  ? 132 PRO A HG2  1 
ATOM   1992 H  HG3  . PRO A 1 152 ? 17.75730  -22.23666 -5.22053  1.000 36.60931  ? 132 PRO A HG3  1 
ATOM   1993 H  HD2  . PRO A 1 152 ? 16.24894  -22.32634 -7.52411  1.000 27.52878  ? 132 PRO A HD2  1 
ATOM   1994 H  HD3  . PRO A 1 152 ? 16.27635  -21.17998 -6.42387  1.000 27.52878  ? 132 PRO A HD3  1 
ATOM   1995 N  N    . LEU A 1 153 ? 19.16869  -22.39154 -9.87810  1.000 19.98331  ? 133 LEU A N    1 
ATOM   1996 C  CA   . LEU A 1 153 ? 19.91821  -22.88632 -11.02926 1.000 21.68427  ? 133 LEU A CA   1 
ATOM   1997 C  C    . LEU A 1 153 ? 20.61694  -21.74293 -11.75319 1.000 21.45589  ? 133 LEU A C    1 
ATOM   1998 O  O    . LEU A 1 153 ? 21.84511  -21.84220 -11.96598 1.000 20.59530  ? 133 LEU A O    1 
ATOM   1999 C  CB   . LEU A 1 153 ? 19.01631  -23.71240 -11.96217 1.000 20.30538  ? 133 LEU A CB   1 
ATOM   2000 C  CG   . LEU A 1 153 ? 19.62123  -24.35005 -13.23584 1.000 22.82022  ? 133 LEU A CG   1 
ATOM   2001 C  CD1  . LEU A 1 153 ? 19.71091  -23.28914 -14.31077 1.000 22.62453  ? 133 LEU A CD1  1 
ATOM   2002 C  CD2  . LEU A 1 153 ? 20.98678  -25.02917 -12.97123 1.000 24.27629  ? 133 LEU A CD2  1 
ATOM   2003 H  H    . LEU A 1 153 ? 18.31406  -22.48158 -9.91123  1.000 24.00374  ? 133 LEU A H    1 
ATOM   2004 H  HA   . LEU A 1 153 ? 20.59429  -23.50366 -10.70879 1.000 26.04488  ? 133 LEU A HA   1 
ATOM   2005 H  HB2  . LEU A 1 153 ? 18.65154  -24.44308 -11.43877 1.000 24.39022  ? 133 LEU A HB2  1 
ATOM   2006 H  HB3  . LEU A 1 153 ? 18.30105  -23.13010 -12.26257 1.000 24.39022  ? 133 LEU A HB3  1 
ATOM   2007 H  HG   . LEU A 1 153 ? 19.04433  -25.06641 -13.54391 1.000 27.40802  ? 133 LEU A HG   1 
ATOM   2008 H  HD11 . LEU A 1 153 ? 19.67179  -23.71675 -15.18055 1.000 27.17319  ? 133 LEU A HD11 1 
ATOM   2009 H  HD12 . LEU A 1 153 ? 18.96725  -22.67445 -14.21063 1.000 27.17319  ? 133 LEU A HD12 1 
ATOM   2010 H  HD13 . LEU A 1 153 ? 20.54985  -22.81189 -14.21425 1.000 27.17319  ? 133 LEU A HD13 1 
ATOM   2011 H  HD21 . LEU A 1 153 ? 21.29010  -25.45699 -13.78724 1.000 29.15531  ? 133 LEU A HD21 1 
ATOM   2012 H  HD22 . LEU A 1 153 ? 21.62641  -24.35475 -12.69386 1.000 29.15531  ? 133 LEU A HD22 1 
ATOM   2013 H  HD23 . LEU A 1 153 ? 20.87963  -25.69143 -12.27064 1.000 29.15531  ? 133 LEU A HD23 1 
ATOM   2014 N  N    . PRO A 1 154 ? 19.94328  -20.64959 -12.15252 1.000 20.13667  ? 134 PRO A N    1 
ATOM   2015 C  CA   . PRO A 1 154 ? 20.68198  -19.59119 -12.86429 1.000 19.98673  ? 134 PRO A CA   1 
ATOM   2016 C  C    . PRO A 1 154 ? 21.76982  -18.97007 -11.99225 1.000 20.12439  ? 134 PRO A C    1 
ATOM   2017 O  O    . PRO A 1 154 ? 22.83551  -18.62886 -12.50893 1.000 22.16586  ? 134 PRO A O    1 
ATOM   2018 C  CB   . PRO A 1 154 ? 19.60326  -18.56631 -13.23904 1.000 21.03258  ? 134 PRO A CB   1 
ATOM   2019 C  CG   . PRO A 1 154 ? 18.28701  -19.40407 -13.24165 1.000 21.22223  ? 134 PRO A CG   1 
ATOM   2020 C  CD   . PRO A 1 154 ? 18.49990  -20.34502 -12.04335 1.000 22.48948  ? 134 PRO A CD   1 
ATOM   2021 H  HA   . PRO A 1 154 ? 21.06336  -19.94097 -13.68472 1.000 24.00784  ? 134 PRO A HA   1 
ATOM   2022 H  HB2  . PRO A 1 154 ? 19.56865  -17.85792 -12.57731 1.000 25.26286  ? 134 PRO A HB2  1 
ATOM   2023 H  HB3  . PRO A 1 154 ? 19.78486  -18.19285 -14.11565 1.000 25.26286  ? 134 PRO A HB3  1 
ATOM   2024 H  HG2  . PRO A 1 154 ? 17.51591  -18.83002 -13.11222 1.000 25.49043  ? 134 PRO A HG2  1 
ATOM   2025 H  HG3  . PRO A 1 154 ? 18.19744  -19.89782 -14.07177 1.000 25.49043  ? 134 PRO A HG3  1 
ATOM   2026 H  HD2  . PRO A 1 154 ? 18.29756  -19.89874 -11.20621 1.000 27.01114  ? 134 PRO A HD2  1 
ATOM   2027 H  HD3  . PRO A 1 154 ? 17.96397  -21.14901 -12.12870 1.000 27.01114  ? 134 PRO A HD3  1 
ATOM   2028 N  N    . MET A 1 155 ? 21.54172  -18.87920 -10.68661 1.000 19.95205  ? 135 MET A N    1 
ATOM   2029 C  CA   . MET A 1 155 ? 22.56071  -18.32564 -9.80173  1.000 20.82830  ? 135 MET A CA   1 
ATOM   2030 C  C    . MET A 1 155 ? 23.80251  -19.18393 -9.78413  1.000 23.31374  ? 135 MET A C    1 
ATOM   2031 O  O    . MET A 1 155 ? 24.92253  -18.66552 -9.83558  1.000 23.60022  ? 135 MET A O    1 
ATOM   2032 C  CB   . MET A 1 155 ? 22.03727  -18.08807 -8.41054  1.000 23.06296  ? 135 MET A CB   1 
ATOM   2033 C  CG   . MET A 1 155 ? 23.09891  -17.75527 -7.38796  1.000 23.30685  ? 135 MET A CG   1 
ATOM   2034 S  SD   . MET A 1 155 ? 23.56790  -15.96264 -7.71339  1.000 25.64924  ? 135 MET A SD   1 
ATOM   2035 C  CE   . MET A 1 155 ? 25.30028  -16.10267 -7.98514  1.000 30.29024  ? 135 MET A CE   1 
ATOM   2036 H  H    . MET A 1 155 ? 20.81807  -19.12636 -10.29312 1.000 23.96622  ? 135 MET A H    1 
ATOM   2037 H  HA   . MET A 1 155 ? 22.79309  -17.44940 -10.14684 1.000 25.01772  ? 135 MET A HA   1 
ATOM   2038 H  HB2  . MET A 1 155 ? 21.41420  -17.34515 -8.43791  1.000 27.69931  ? 135 MET A HB2  1 
ATOM   2039 H  HB3  . MET A 1 155 ? 21.58325  -18.89096 -8.11033  1.000 27.69931  ? 135 MET A HB3  1 
ATOM   2040 H  HG2  . MET A 1 155 ? 22.74914  -17.84650 -6.48782  1.000 27.99198  ? 135 MET A HG2  1 
ATOM   2041 H  HG3  . MET A 1 155 ? 23.87555  -18.32521 -7.50146  1.000 27.99198  ? 135 MET A HG3  1 
ATOM   2042 H  HE1  . MET A 1 155 ? 25.68193  -15.21361 -8.05457  1.000 36.37205  ? 135 MET A HE1  1 
ATOM   2043 H  HE2  . MET A 1 155 ? 25.69967  -16.57675 -7.23906  1.000 36.37205  ? 135 MET A HE2  1 
ATOM   2044 H  HE3  . MET A 1 155 ? 25.45222  -16.59306 -8.80814  1.000 36.37205  ? 135 MET A HE3  1 
ATOM   2045 N  N    . ALA A 1 156 ? 23.62780  -20.49914 -9.74023  1.000 21.22288  ? 136 ALA A N    1 
ATOM   2046 C  CA   . ALA A 1 156 ? 24.77877  -21.38040 -9.69525  1.000 22.37965  ? 136 ALA A CA   1 
ATOM   2047 C  C    . ALA A 1 156 ? 25.55314  -21.30761 -11.00928 1.000 22.62634  ? 136 ALA A C    1 
ATOM   2048 O  O    . ALA A 1 156 ? 26.79030  -21.30898 -11.00491 1.000 23.19758  ? 136 ALA A O    1 
ATOM   2049 C  CB   . ALA A 1 156 ? 24.33131  -22.82004 -9.41731  1.000 22.57741  ? 136 ALA A CB   1 
ATOM   2050 H  H    . ALA A 1 156 ? 22.86568  -20.89758 -9.73564  1.000 25.49122  ? 136 ALA A H    1 
ATOM   2051 H  HA   . ALA A 1 156 ? 25.36374  -21.10747 -8.97122  1.000 26.87934  ? 136 ALA A HA   1 
ATOM   2052 H  HB1  . ALA A 1 156 ? 25.11254  -23.39450 -9.39330  1.000 27.11665  ? 136 ALA A HB1  1 
ATOM   2053 H  HB2  . ALA A 1 156 ? 23.87310  -22.84893 -8.56284  1.000 27.11665  ? 136 ALA A HB2  1 
ATOM   2054 H  HB3  . ALA A 1 156 ? 23.73175  -23.10640 -10.12401 1.000 27.11665  ? 136 ALA A HB3  1 
ATOM   2055 N  N    . VAL A 1 157 ? 24.83892  -21.22387 -12.14261 1.000 21.64434  ? 137 VAL A N    1 
ATOM   2056 C  CA   . VAL A 1 157 ? 25.52041  -21.16530 -13.43247 1.000 22.08800  ? 137 VAL A CA   1 
ATOM   2057 C  C    . VAL A 1 157 ? 26.36841  -19.90828 -13.52931 1.000 24.38043  ? 137 VAL A C    1 
ATOM   2058 O  O    . VAL A 1 157 ? 27.56571  -19.96301 -13.87436 1.000 24.02223  ? 137 VAL A O    1 
ATOM   2059 C  CB   . VAL A 1 157 ? 24.50919  -21.22641 -14.58902 1.000 19.77968  ? 137 VAL A CB   1 
ATOM   2060 C  CG1  . VAL A 1 157 ? 25.16463  -20.94050 -15.93341 1.000 23.99034  ? 137 VAL A CG1  1 
ATOM   2061 C  CG2  . VAL A 1 157 ? 23.82125  -22.61299 -14.60786 1.000 22.16437  ? 137 VAL A CG2  1 
ATOM   2062 H  H    . VAL A 1 157 ? 23.98030  -21.20027 -12.18527 1.000 25.99697  ? 137 VAL A H    1 
ATOM   2063 H  HA   . VAL A 1 157 ? 26.10352  -21.93795 -13.49492 1.000 26.52936  ? 137 VAL A HA   1 
ATOM   2064 H  HB   . VAL A 1 157 ? 23.84093  -20.53780 -14.44708 1.000 23.75938  ? 137 VAL A HB   1 
ATOM   2065 H  HG11 . VAL A 1 157 ? 24.57886  -21.24910 -16.64231 1.000 28.81217  ? 137 VAL A HG11 1 
ATOM   2066 H  HG12 . VAL A 1 157 ? 25.31019  -19.98513 -16.01696 1.000 28.81217  ? 137 VAL A HG12 1 
ATOM   2067 H  HG13 . VAL A 1 157 ? 26.01263  -21.40940 -15.97739 1.000 28.81217  ? 137 VAL A HG13 1 
ATOM   2068 H  HG21 . VAL A 1 157 ? 23.18704  -22.64093 -15.34127 1.000 26.62101  ? 137 VAL A HG21 1 
ATOM   2069 H  HG22 . VAL A 1 157 ? 24.49648  -23.29893 -14.72814 1.000 26.62101  ? 137 VAL A HG22 1 
ATOM   2070 H  HG23 . VAL A 1 157 ? 23.35920  -22.74775 -13.76568 1.000 26.62101  ? 137 VAL A HG23 1 
ATOM   2071 N  N    . ILE A 1 158 ? 25.75532  -18.75343 -13.25128 1.000 22.60073  ? 138 ILE A N    1 
ATOM   2072 C  CA   . ILE A 1 158 ? 26.47780  -17.49866 -13.43810 1.000 23.98584  ? 138 ILE A CA   1 
ATOM   2073 C  C    . ILE A 1 158 ? 27.53398  -17.34966 -12.34376 1.000 26.84583  ? 138 ILE A C    1 
ATOM   2074 O  O    . ILE A 1 158 ? 28.62921  -16.82038 -12.59086 1.000 26.66450  ? 138 ILE A O    1 
ATOM   2075 C  CB   . ILE A 1 158 ? 25.50748  -16.31024 -13.50184 1.000 22.78962  ? 138 ILE A CB   1 
ATOM   2076 C  CG1  . ILE A 1 158 ? 26.12045  -15.19668 -14.35765 1.000 27.02005  ? 138 ILE A CG1  1 
ATOM   2077 C  CG2  . ILE A 1 158 ? 25.08775  -15.81768 -12.13491 1.000 23.23860  ? 138 ILE A CG2  1 
ATOM   2078 C  CD1  . ILE A 1 158 ? 26.16186  -15.52726 -15.86412 1.000 28.42095  ? 138 ILE A CD1  1 
ATOM   2079 H  H    . ILE A 1 158 ? 24.94894  -18.67413 -12.96309 1.000 27.14464  ? 138 ILE A H    1 
ATOM   2080 H  HA   . ILE A 1 158 ? 26.93568  -17.51551 -14.29306 1.000 28.80677  ? 138 ILE A HA   1 
ATOM   2081 H  HB   . ILE A 1 158 ? 24.68907  -16.61552 -13.92364 1.000 27.37131  ? 138 ILE A HB   1 
ATOM   2082 H  HG12 . ILE A 1 158 ? 25.59341  -14.39015 -14.24523 1.000 32.44782  ? 138 ILE A HG12 1 
ATOM   2083 H  HG13 . ILE A 1 158 ? 27.03142  -15.04149 -14.06277 1.000 32.44782  ? 138 ILE A HG13 1 
ATOM   2084 H  HG21 . ILE A 1 158 ? 24.30257  -15.25596 -12.22902 1.000 27.91008  ? 138 ILE A HG21 1 
ATOM   2085 H  HG22 . ILE A 1 158 ? 24.88266  -16.58148 -11.57326 1.000 27.91008  ? 138 ILE A HG22 1 
ATOM   2086 H  HG23 . ILE A 1 158 ? 25.81510  -15.30705 -11.74617 1.000 27.91008  ? 138 ILE A HG23 1 
ATOM   2087 H  HD11 . ILE A 1 158 ? 26.47512  -14.74828 -16.34988 1.000 34.12890  ? 138 ILE A HD11 1 
ATOM   2088 H  HD12 . ILE A 1 158 ? 26.76678  -16.27184 -16.00753 1.000 34.12890  ? 138 ILE A HD12 1 
ATOM   2089 H  HD13 . ILE A 1 158 ? 25.26911  -15.76465 -16.16000 1.000 34.12890  ? 138 ILE A HD13 1 
ATOM   2090 N  N    . GLY A 1 159 ? 27.25222  -17.85054 -11.14112 1.000 23.62091  ? 139 GLY A N    1 
ATOM   2091 C  CA   . GLY A 1 159 ? 28.25487  -17.84845 -10.08939 1.000 25.99187  ? 139 GLY A CA   1 
ATOM   2092 C  C    . GLY A 1 159 ? 29.46866  -18.66762 -10.46729 1.000 26.98701  ? 139 GLY A C    1 
ATOM   2093 O  O    . GLY A 1 159 ? 30.61372  -18.23696 -10.28316 1.000 29.15483  ? 139 GLY A O    1 
ATOM   2094 H  H    . GLY A 1 159 ? 26.49649  -18.19260 -10.91425 1.000 28.36885  ? 139 GLY A H    1 
ATOM   2095 H  HA2  . GLY A 1 159 ? 28.53972  -16.93750 -9.91639  1.000 31.21401  ? 139 GLY A HA2  1 
ATOM   2096 H  HA3  . GLY A 1 159 ? 27.87321  -18.21938 -9.27843  1.000 31.21401  ? 139 GLY A HA3  1 
ATOM   2097 N  N    . ASP A 1 160 ? 29.24437  -19.84578 -11.04284 1.000 26.15609  ? 140 ASP A N    1 
ATOM   2098 C  CA   . ASP A 1 160 ? 30.37892  -20.65754 -11.46477 1.000 27.36273  ? 140 ASP A CA   1 
ATOM   2099 C  C    . ASP A 1 160 ? 31.20343  -19.94395 -12.53513 1.000 28.63034  ? 140 ASP A C    1 
ATOM   2100 O  O    . ASP A 1 160 ? 32.44674  -20.03483 -12.52382 1.000 31.25546  ? 140 ASP A O    1 
ATOM   2101 C  CB   . ASP A 1 160 ? 29.90597  -22.02107 -11.95117 1.000 29.11873  ? 140 ASP A CB   1 
ATOM   2102 C  CG   . ASP A 1 160 ? 29.52508  -22.96466 -10.80153 1.000 29.55159  ? 140 ASP A CG   1 
ATOM   2103 O  OD1  . ASP A 1 160 ? 29.57337  -22.57963 -9.60862  1.000 30.60505  ? 140 ASP A OD1  1 
ATOM   2104 O  OD2  . ASP A 1 160 ? 29.16730  -24.12737 -11.09774 1.000 32.52895  ? 140 ASP A OD2  1 
ATOM   2105 H  H    . ASP A 1 160 ? 28.46987  -20.18699 -11.19557 1.000 31.41107  ? 140 ASP A H    1 
ATOM   2106 H  HA   . ASP A 1 160 ? 30.95606  -20.80809 -10.69983 1.000 32.85904  ? 140 ASP A HA   1 
ATOM   2107 H  HB2  . ASP A 1 160 ? 29.12406  -21.90223 -12.51277 1.000 34.96624  ? 140 ASP A HB2  1 
ATOM   2108 H  HB3  . ASP A 1 160 ? 30.61855  -22.43983 -12.45887 1.000 34.96624  ? 140 ASP A HB3  1 
ATOM   2109 N  N    . MET A 1 161 ? 30.53681  -19.23570 -13.45637 1.000 28.33101  ? 141 MET A N    1 
ATOM   2110 C  CA   . MET A 1 161 ? 31.24051  -18.47714 -14.48915 1.000 28.02000  ? 141 MET A CA   1 
ATOM   2111 C  C    . MET A 1 161 ? 32.08954  -17.35412 -13.88442 1.000 30.25353  ? 141 MET A C    1 
ATOM   2112 O  O    . MET A 1 161 ? 33.14222  -16.98341 -14.43494 1.000 30.11509  ? 141 MET A O    1 
ATOM   2113 C  CB   . MET A 1 161 ? 30.23964  -17.88135 -15.47798 1.000 28.69518  ? 141 MET A CB   1 
ATOM   2114 C  CG   . MET A 1 161 ? 29.80932  -18.86814 -16.51889 1.000 32.36320  ? 141 MET A CG   1 
ATOM   2115 S  SD   . MET A 1 161 ? 28.30928  -18.37258 -17.36842 1.000 34.83058  ? 141 MET A SD   1 
ATOM   2116 C  CE   . MET A 1 161 ? 28.77525  -16.79781 -18.04125 1.000 41.44453  ? 141 MET A CE   1 
ATOM   2117 H  H    . MET A 1 161 ? 29.67990  -19.17971 -13.50302 1.000 34.02097  ? 141 MET A H    1 
ATOM   2118 H  HA   . MET A 1 161 ? 31.81799  -19.08951 -14.97125 1.000 33.64776  ? 141 MET A HA   1 
ATOM   2119 H  HB2  . MET A 1 161 ? 29.45114  -17.58984 -14.99406 1.000 34.45798  ? 141 MET A HB2  1 
ATOM   2120 H  HB3  . MET A 1 161 ? 30.65011  -17.12684 -15.92867 1.000 34.45798  ? 141 MET A HB3  1 
ATOM   2121 H  HG2  . MET A 1 161 ? 30.51319  -18.95669 -17.18041 1.000 38.85960  ? 141 MET A HG2  1 
ATOM   2122 H  HG3  . MET A 1 161 ? 29.64414  -19.72414 -16.09359 1.000 38.85960  ? 141 MET A HG3  1 
ATOM   2123 H  HE1  . MET A 1 161 ? 28.03234  -16.44049 -18.55244 1.000 49.75719  ? 141 MET A HE1  1 
ATOM   2124 H  HE2  . MET A 1 161 ? 28.99557  -16.19600 -17.31311 1.000 49.75719  ? 141 MET A HE2  1 
ATOM   2125 H  HE3  . MET A 1 161 ? 29.54658  -16.91629 -18.61736 1.000 49.75719  ? 141 MET A HE3  1 
ATOM   2126 N  N    . LEU A 1 162 ? 31.64039  -16.78117 -12.77329 1.000 29.53964  ? 142 LEU A N    1 
ATOM   2127 C  CA   . LEU A 1 162 ? 32.35813  -15.67528 -12.14667 1.000 33.03160  ? 142 LEU A CA   1 
ATOM   2128 C  C    . LEU A 1 162 ? 33.26328  -16.09906 -10.99209 1.000 34.00038  ? 142 LEU A C    1 
ATOM   2129 O  O    . LEU A 1 162 ? 33.85217  -15.22818 -10.34656 1.000 38.05607  ? 142 LEU A O    1 
ATOM   2130 C  CB   . LEU A 1 162 ? 31.34297  -14.62272 -11.68129 1.000 28.55450  ? 142 LEU A CB   1 
ATOM   2131 C  CG   . LEU A 1 162 ? 30.58312  -13.83659 -12.74352 1.000 30.81630  ? 142 LEU A CG   1 
ATOM   2132 C  CD1  . LEU A 1 162 ? 29.38876  -13.10913 -12.08872 1.000 31.63222  ? 142 LEU A CD1  1 
ATOM   2133 C  CD2  . LEU A 1 162 ? 31.51558  -12.82394 -13.44902 1.000 35.70179  ? 142 LEU A CD2  1 
ATOM   2134 H  H    . LEU A 1 162 ? 30.92175  -17.01513 -12.36290 1.000 35.47133  ? 142 LEU A H    1 
ATOM   2135 H  HA   . LEU A 1 162 ? 32.94299  -15.27257 -12.80748 1.000 39.66168  ? 142 LEU A HA   1 
ATOM   2136 H  HB2  . LEU A 1 162 ? 30.67660  -15.07579 -11.14131 1.000 34.28916  ? 142 LEU A HB2  1 
ATOM   2137 H  HB3  . LEU A 1 162 ? 31.82015  -13.97229 -11.14264 1.000 34.28916  ? 142 LEU A HB3  1 
ATOM   2138 H  HG   . LEU A 1 162 ? 30.24793  -14.44557 -13.42004 1.000 37.00332  ? 142 LEU A HG   1 
ATOM   2139 H  HD11 . LEU A 1 162 ? 28.90796  -12.61440 -12.77060 1.000 37.98243  ? 142 LEU A HD11 1 
ATOM   2140 H  HD12 . LEU A 1 162 ? 28.80289  -13.76667 -11.68214 1.000 37.98243  ? 142 LEU A HD12 1 
ATOM   2141 H  HD13 . LEU A 1 162 ? 29.72265  -12.50002 -11.41167 1.000 37.98243  ? 142 LEU A HD13 1 
ATOM   2142 H  HD21 . LEU A 1 162 ? 30.99056  -12.28406 -14.06040 1.000 42.86590  ? 142 LEU A HD21 1 
ATOM   2143 H  HD22 . LEU A 1 162 ? 31.93026  -12.25721 -12.77987 1.000 42.86590  ? 142 LEU A HD22 1 
ATOM   2144 H  HD23 . LEU A 1 162 ? 32.19702  -13.31032 -13.93889 1.000 42.86590  ? 142 LEU A HD23 1 
ATOM   2145 N  N    . GLY A 1 163 ? 33.40848  -17.40050 -10.71573 1.000 30.11285  ? 143 GLY A N    1 
ATOM   2146 C  CA   . GLY A 1 163 ? 34.32888  -17.85928 -9.68744  1.000 33.18728  ? 143 GLY A CA   1 
ATOM   2147 C  C    . GLY A 1 163 ? 33.80316  -17.80894 -8.26678  1.000 32.86527  ? 143 GLY A C    1 
ATOM   2148 O  O    . GLY A 1 163 ? 34.60268  -17.79715 -7.31441  1.000 36.88557  ? 143 GLY A O    1 
ATOM   2149 H  H    . GLY A 1 163 ? 32.98246  -18.03303 -11.11323 1.000 36.15918  ? 143 GLY A H    1 
ATOM   2150 H  HA2  . GLY A 1 163 ? 34.56886  -18.77961 -9.87796  1.000 39.84849  ? 143 GLY A HA2  1 
ATOM   2151 H  HA3  . GLY A 1 163 ? 35.12804  -17.31067 -9.72309  1.000 39.84849  ? 143 GLY A HA3  1 
ATOM   2152 N  N    . VAL A 1 164 ? 32.47745  -17.76937 -8.09866  1.000 32.46293  ? 144 VAL A N    1 
ATOM   2153 C  CA   . VAL A 1 164 ? 31.84649  -17.70923 -6.78380  1.000 30.06836  ? 144 VAL A CA   1 
ATOM   2154 C  C    . VAL A 1 164 ? 31.81889  -19.10709 -6.17895  1.000 34.33174  ? 144 VAL A C    1 
ATOM   2155 O  O    . VAL A 1 164 ? 31.35251  -20.04958 -6.81932  1.000 33.98171  ? 144 VAL A O    1 
ATOM   2156 C  CB   . VAL A 1 164 ? 30.42046  -17.13029 -6.88651  1.000 30.65632  ? 144 VAL A CB   1 
ATOM   2157 C  CG1  . VAL A 1 164 ? 29.75352  -17.08571 -5.47124  1.000 31.05284  ? 144 VAL A CG1  1 
ATOM   2158 C  CG2  . VAL A 1 164 ? 30.39442  -15.73530 -7.59277  1.000 31.41557  ? 144 VAL A CG2  1 
ATOM   2159 H  H    . VAL A 1 164 ? 31.91217  -17.77658 -8.74674  1.000 38.97927  ? 144 VAL A H    1 
ATOM   2160 H  HA   . VAL A 1 164 ? 32.37360  -17.13296 -6.20850  1.000 36.10580  ? 144 VAL A HA   1 
ATOM   2161 H  HB   . VAL A 1 164 ? 29.89205  -17.71779 -7.44911  1.000 36.81135  ? 144 VAL A HB   1 
ATOM   2162 H  HG11 . VAL A 1 164 ? 28.97598  -16.50684 -5.50664  1.000 37.28717  ? 144 VAL A HG11 1 
ATOM   2163 H  HG12 . VAL A 1 164 ? 29.48626  -17.98358 -5.21965  1.000 37.28717  ? 144 VAL A HG12 1 
ATOM   2164 H  HG13 . VAL A 1 164 ? 30.39461  -16.73972 -4.83078  1.000 37.28717  ? 144 VAL A HG13 1 
ATOM   2165 H  HG21 . VAL A 1 164 ? 29.48697  -15.39279 -7.58205  1.000 37.72245  ? 144 VAL A HG21 1 
ATOM   2166 H  HG22 . VAL A 1 164 ? 30.98250  -15.12890 -7.11595  1.000 37.72245  ? 144 VAL A HG22 1 
ATOM   2167 H  HG23 . VAL A 1 164 ? 30.69803  -15.83907 -8.50817  1.000 37.72245  ? 144 VAL A HG23 1 
ATOM   2168 N  N    . ARG A 1 165 ? 32.31903  -19.24760 -4.94672  1.000 31.60345  ? 145 ARG A N    1 
ATOM   2169 C  CA   . ARG A 1 165 ? 32.25335  -20.52555 -4.24659  1.000 33.57324  ? 145 ARG A CA   1 
ATOM   2170 C  C    . ARG A 1 165 ? 30.79084  -20.90383 -3.99521  1.000 32.20456  ? 145 ARG A C    1 
ATOM   2171 O  O    . ARG A 1 165 ? 29.95760  -20.03104 -3.73258  1.000 31.14218  ? 145 ARG A O    1 
ATOM   2172 C  CB   . ARG A 1 165 ? 33.01544  -20.47292 -2.92220  1.000 37.32597  ? 145 ARG A CB   1 
ATOM   2173 C  CG   . ARG A 1 165 ? 34.50209  -20.22744 -3.10631  1.000 42.78075  ? 145 ARG A CG   1 
ATOM   2174 C  CD   . ARG A 1 165 ? 35.22823  -20.31615 -1.78447  1.000 48.38713  ? 145 ARG A CD   1 
ATOM   2175 N  NE   . ARG A 1 165 ? 35.31476  -21.69684 -1.32955  1.000 50.51156  ? 145 ARG A NE   1 
ATOM   2176 C  CZ   . ARG A 1 165 ? 36.30629  -22.52064 -1.63905  1.000 63.22953  ? 145 ARG A CZ   1 
ATOM   2177 N  NH1  . ARG A 1 165 ? 37.29669  -22.14293 -2.43438  1.000 63.74613  ? 145 ARG A NH1  1 
ATOM   2178 N  NH2  . ARG A 1 165 ? 36.30495  -23.75302 -1.13885  1.000 61.51237  ? 145 ARG A NH2  1 
ATOM   2179 H  H    . ARG A 1 165 ? 32.69916  -18.61955 -4.49877  1.000 37.94790  ? 145 ARG A H    1 
ATOM   2180 H  HA   . ARG A 1 165 ? 32.66523  -21.21031 -4.79645  1.000 40.31165  ? 145 ARG A HA   1 
ATOM   2181 H  HB2  . ARG A 1 165 ? 32.65725  -19.75214 -2.38083  1.000 44.81493  ? 145 ARG A HB2  1 
ATOM   2182 H  HB3  . ARG A 1 165 ? 32.90606  -21.31961 -2.46172  1.000 44.81493  ? 145 ARG A HB3  1 
ATOM   2183 H  HG2  . ARG A 1 165 ? 34.86929  -20.89673 -3.70473  1.000 51.36066  ? 145 ARG A HG2  1 
ATOM   2184 H  HG3  . ARG A 1 165 ? 34.64087  -19.34097 -3.47484  1.000 51.36066  ? 145 ARG A HG3  1 
ATOM   2185 H  HD2  . ARG A 1 165 ? 36.12827  -19.96907 -1.88622  1.000 58.08831  ? 145 ARG A HD2  1 
ATOM   2186 H  HD3  . ARG A 1 165 ? 34.74791  -19.80203 -1.11673  1.000 58.08831  ? 145 ARG A HD3  1 
ATOM   2187 H  HE   . ARG A 1 165 ? 34.68311  -21.99657 -0.82877  1.000 60.63763  ? 145 ARG A HE   1 
ATOM   2188 H  HH11 . ARG A 1 165 ? 37.30563  -21.34788 -2.76214  1.000 76.51912  ? 145 ARG A HH11 1 
ATOM   2189 H  HH12 . ARG A 1 165 ? 37.93048  -22.69285 -2.62277  1.000 76.51912  ? 145 ARG A HH12 1 
ATOM   2190 H  HH21 . ARG A 1 165 ? 35.66624  -24.00652 -0.62175  1.000 73.83861  ? 145 ARG A HH21 1 
ATOM   2191 H  HH22 . ARG A 1 165 ? 36.94279  -24.29639 -1.33251  1.000 73.83861  ? 145 ARG A HH22 1 
ATOM   2192 N  N    . PRO A 1 166 ? 30.44086  -22.19006 -4.08170  1.000 29.82297  ? 146 PRO A N    1 
ATOM   2193 C  CA   . PRO A 1 166 ? 29.03742  -22.56958 -3.86500  1.000 29.25266  ? 146 PRO A CA   1 
ATOM   2194 C  C    . PRO A 1 166 ? 28.44038  -22.02263 -2.58336  1.000 27.56657  ? 146 PRO A C    1 
ATOM   2195 O  O    . PRO A 1 166 ? 27.31463  -21.51648 -2.59482  1.000 28.09017  ? 146 PRO A O    1 
ATOM   2196 C  CB   . PRO A 1 166 ? 29.09133  -24.10426 -3.87962  1.000 29.05777  ? 146 PRO A CB   1 
ATOM   2197 C  CG   . PRO A 1 166 ? 30.25178  -24.42023 -4.77666  1.000 39.82894  ? 146 PRO A CG   1 
ATOM   2198 C  CD   . PRO A 1 166 ? 31.27563  -23.33348 -4.50945  1.000 34.70078  ? 146 PRO A CD   1 
ATOM   2199 H  HA   . PRO A 1 166 ? 28.49796  -22.26297 -4.61058  1.000 35.12695  ? 146 PRO A HA   1 
ATOM   2200 H  HB2  . PRO A 1 166 ? 29.23989  -24.44166 -2.98240  1.000 34.89309  ? 146 PRO A HB2  1 
ATOM   2201 H  HB3  . PRO A 1 166 ? 28.26427  -24.46399 -4.23663  1.000 34.89309  ? 146 PRO A HB3  1 
ATOM   2202 H  HG2  . PRO A 1 166 ? 30.61019  -25.29401 -4.55539  1.000 47.81849  ? 146 PRO A HG2  1 
ATOM   2203 H  HG3  . PRO A 1 166 ? 29.96521  -24.40413 -5.70322  1.000 47.81849  ? 146 PRO A HG3  1 
ATOM   2204 H  HD2  . PRO A 1 166 ? 31.88702  -23.59902 -3.80477  1.000 41.66469  ? 146 PRO A HD2  1 
ATOM   2205 H  HD3  . PRO A 1 166 ? 31.77122  -23.11855 -5.31511  1.000 41.66469  ? 146 PRO A HD3  1 
ATOM   2206 N  N    . GLU A 1 167 ? 29.18958  -22.06879 -1.46376  1.000 28.63505  ? 147 GLU A N    1 
ATOM   2207 C  CA   . GLU A 1 167 ? 28.67139  -21.59127 -0.18350  1.000 29.98904  ? 147 GLU A CA   1 
ATOM   2208 C  C    . GLU A 1 167 ? 28.59416  -20.06282 -0.10207  1.000 27.62694  ? 147 GLU A C    1 
ATOM   2209 O  O    . GLU A 1 167 ? 28.03977  -19.55516 0.86986   1.000 31.28431  ? 147 GLU A O    1 
ATOM   2210 C  CB   . GLU A 1 167 ? 29.53721  -22.13959 0.95989   1.000 36.04467  ? 147 GLU A CB   1 
ATOM   2211 C  CG   . GLU A 1 167 ? 30.97141  -21.60207 1.03823   1.000 36.12541  ? 147 GLU A CG   1 
ATOM   2212 C  CD   . GLU A 1 167 ? 31.99737  -22.38984 0.20718   1.000 42.92072  ? 147 GLU A CD   1 
ATOM   2213 O  OE1  . GLU A 1 167 ? 31.62786  -23.09854 -0.76108  1.000 36.01376  ? 147 GLU A OE1  1 
ATOM   2214 O  OE2  . GLU A 1 167 ? 33.20355  -22.27850 0.52270   1.000 42.93462  ? 147 GLU A OE2  1 
ATOM   2215 H  H    . GLU A 1 167 ? 29.99384  -22.37130 -1.42825  1.000 34.38582  ? 147 GLU A H    1 
ATOM   2216 H  HA   . GLU A 1 167 ? 27.77073  -21.93097 -0.06383  1.000 36.01062  ? 147 GLU A HA   1 
ATOM   2217 H  HB2  . GLU A 1 167 ? 29.10354  -21.92087 1.79953   1.000 43.27737  ? 147 GLU A HB2  1 
ATOM   2218 H  HB3  . GLU A 1 167 ? 29.59775  -23.10239 0.85869   1.000 43.27737  ? 147 GLU A HB3  1 
ATOM   2219 H  HG2  . GLU A 1 167 ? 30.97624  -20.68691 0.71673   1.000 43.37426  ? 147 GLU A HG2  1 
ATOM   2220 H  HG3  . GLU A 1 167 ? 31.26169  -21.63025 1.96335   1.000 43.37426  ? 147 GLU A HG3  1 
ATOM   2221 N  N    . GLN A 1 168 ? 29.04847  -19.32681 -1.12008  1.000 30.09507  ? 148 GLN A N    1 
ATOM   2222 C  CA   . GLN A 1 168 ? 28.87265  -17.88056 -1.19212  1.000 29.43410  ? 148 GLN A CA   1 
ATOM   2223 C  C    . GLN A 1 168 ? 27.81910  -17.45401 -2.21075  1.000 29.26518  ? 148 GLN A C    1 
ATOM   2224 O  O    . GLN A 1 168 ? 27.56896  -16.25427 -2.37667  1.000 28.50898  ? 148 GLN A O    1 
ATOM   2225 C  CB   . GLN A 1 168 ? 30.23154  -17.23777 -1.49311  1.000 35.31126  ? 148 GLN A CB   1 
ATOM   2226 C  CG   . GLN A 1 168 ? 31.19893  -17.54071 -0.32947  1.000 39.43712  ? 148 GLN A CG   1 
ATOM   2227 C  CD   . GLN A 1 168 ? 32.55399  -16.85044 -0.42054  1.000 57.29550  ? 148 GLN A CD   1 
ATOM   2228 O  OE1  . GLN A 1 168 ? 32.74266  -15.94605 -1.24446  1.000 44.85829  ? 148 GLN A OE1  1 
ATOM   2229 N  NE2  . GLN A 1 168 ? 33.52095  -17.29832 0.43008   1.000 46.09424  ? 148 GLN A NE2  1 
ATOM   2230 H  H    . GLN A 1 168 ? 29.47083  -19.65308 -1.79444  1.000 36.13785  ? 148 GLN A H    1 
ATOM   2231 H  HA   . GLN A 1 168 ? 28.56616  -17.54049 -0.33695  1.000 35.34469  ? 148 GLN A HA   1 
ATOM   2232 H  HB2  . GLN A 1 168 ? 30.59702  -17.60680 -2.31233  1.000 42.39727  ? 148 GLN A HB2  1 
ATOM   2233 H  HB3  . GLN A 1 168 ? 30.13050  -16.27681 -1.57824  1.000 42.39727  ? 148 GLN A HB3  1 
ATOM   2234 H  HG2  . GLN A 1 168 ? 30.78262  -17.25447 0.49857   1.000 47.34831  ? 148 GLN A HG2  1 
ATOM   2235 H  HG3  . GLN A 1 168 ? 31.36136  -18.49672 -0.30597  1.000 47.34831  ? 148 GLN A HG3  1 
ATOM   2236 H  HE21 . GLN A 1 168 ? 33.34850  -17.93776 0.97869   1.000 55.33685  ? 148 GLN A HE21 1 
ATOM   2237 H  HE22 . GLN A 1 168 ? 34.30328  -16.94137 0.41797   1.000 55.33685  ? 148 GLN A HE22 1 
ATOM   2238 N  N    . ARG A 1 169 ? 27.16074  -18.40563 -2.87536  1.000 26.54386  ? 149 ARG A N    1 
ATOM   2239 C  CA   . ARG A 1 169 ? 26.13376  -18.04195 -3.83304  1.000 24.31114  ? 149 ARG A CA   1 
ATOM   2240 C  C    . ARG A 1 169 ? 25.04357  -17.21728 -3.17845  1.000 26.03479  ? 149 ARG A C    1 
ATOM   2241 O  O    . ARG A 1 169 ? 24.57620  -16.23021 -3.75348  1.000 23.78530  ? 149 ARG A O    1 
ATOM   2242 C  CB   . ARG A 1 169 ? 25.53683  -19.30107 -4.46866  1.000 24.21507  ? 149 ARG A CB   1 
ATOM   2243 C  CG   . ARG A 1 169 ? 26.43424  -19.93999 -5.51095  1.000 24.32880  ? 149 ARG A CG   1 
ATOM   2244 C  CD   . ARG A 1 169 ? 25.99118  -21.37313 -5.81694  1.000 24.60101  ? 149 ARG A CD   1 
ATOM   2245 N  NE   . ARG A 1 169 ? 26.90109  -22.04563 -6.71975  1.000 24.16508  ? 149 ARG A NE   1 
ATOM   2246 C  CZ   . ARG A 1 169 ? 26.93157  -23.35684 -6.89427  1.000 26.22956  ? 149 ARG A CZ   1 
ATOM   2247 N  NH1  . ARG A 1 169 ? 26.08942  -24.14825 -6.25594  1.000 26.21068  ? 149 ARG A NH1  1 
ATOM   2248 N  NH2  . ARG A 1 169 ? 27.81849  -23.87629 -7.74222  1.000 30.77826  ? 149 ARG A NH2  1 
ATOM   2249 H  H    . ARG A 1 169 ? 27.29126  -19.25115 -2.78785  1.000 31.87640  ? 149 ARG A H    1 
ATOM   2250 H  HA   . ARG A 1 169 ? 26.53811  -17.51008 -4.53626  1.000 29.19713  ? 149 ARG A HA   1 
ATOM   2251 H  HB2  . ARG A 1 169 ? 25.37756  -19.95703 -3.77206  1.000 29.08185  ? 149 ARG A HB2  1 
ATOM   2252 H  HB3  . ARG A 1 169 ? 24.70073  -19.06636 -4.90079  1.000 29.08185  ? 149 ARG A HB3  1 
ATOM   2253 H  HG2  . ARG A 1 169 ? 26.39314  -19.42472 -6.33175  1.000 29.21832  ? 149 ARG A HG2  1 
ATOM   2254 H  HG3  . ARG A 1 169 ? 27.34580  -19.96509 -5.18028  1.000 29.21832  ? 149 ARG A HG3  1 
ATOM   2255 H  HD2  . ARG A 1 169 ? 25.95679  -21.87922 -4.99014  1.000 29.54497  ? 149 ARG A HD2  1 
ATOM   2256 H  HD3  . ARG A 1 169 ? 25.11412  -21.35382 -6.23082  1.000 29.54497  ? 149 ARG A HD3  1 
ATOM   2257 H  HE   . ARG A 1 169 ? 27.45448  -21.56459 -7.16916  1.000 29.02186  ? 149 ARG A HE   1 
ATOM   2258 H  HH11 . ARG A 1 169 ? 25.50925  -23.81327 -5.71670  1.000 31.47657  ? 149 ARG A HH11 1 
ATOM   2259 H  HH12 . ARG A 1 169 ? 26.12103  -24.99876 -6.37938  1.000 31.47657  ? 149 ARG A HH12 1 
ATOM   2260 H  HH21 . ARG A 1 169 ? 28.36047  -23.36090 -8.16676  1.000 36.95768  ? 149 ARG A HH21 1 
ATOM   2261 H  HH22 . ARG A 1 169 ? 27.84895  -24.72694 -7.86496  1.000 36.95768  ? 149 ARG A HH22 1 
ATOM   2262 N  N    . ASP A 1 170 ? 24.61555  -17.60106 -1.98107  1.000 25.34668  ? 150 ASP A N    1 
ATOM   2263 C  CA   . ASP A 1 170 ? 23.51134  -16.89370 -1.32810  1.000 26.24586  ? 150 ASP A CA   1 
ATOM   2264 C  C    . ASP A 1 170 ? 23.85580  -15.43548 -1.03737  1.000 26.80040  ? 150 ASP A C    1 
ATOM   2265 O  O    . ASP A 1 170 ? 22.99920  -14.54446 -1.19122  1.000 27.37678  ? 150 ASP A O    1 
ATOM   2266 C  CB   . ASP A 1 170 ? 23.13172  -17.61719 -0.03872  1.000 30.43419  ? 150 ASP A CB   1 
ATOM   2267 C  CG   . ASP A 1 170 ? 22.21917  -18.80399 -0.29014  1.000 43.24572  ? 150 ASP A CG   1 
ATOM   2268 O  OD1  . ASP A 1 170 ? 21.64358  -18.88040 -1.39646  1.000 51.62162  ? 150 ASP A OD1  1 
ATOM   2269 O  OD2  . ASP A 1 170 ? 22.08746  -19.65350 0.63159   1.000 49.19766  ? 150 ASP A OD2  1 
ATOM   2270 H  H    . ASP A 1 170 ? 24.93916  -18.25695 -1.52864  1.000 30.43978  ? 150 ASP A H    1 
ATOM   2271 H  HA   . ASP A 1 170 ? 22.74757  -16.89776 -1.92605  1.000 31.51879  ? 150 ASP A HA   1 
ATOM   2272 H  HB2  . ASP A 1 170 ? 23.93763  -17.94227 0.39224   1.000 36.54479  ? 150 ASP A HB2  1 
ATOM   2273 H  HB3  . ASP A 1 170 ? 22.66814  -16.99907 0.54772   1.000 36.54479  ? 150 ASP A HB3  1 
ATOM   2274 N  N    . MET A 1 171 ? 25.12557  -15.17407 -0.71933  1.000 27.92471  ? 151 MET A N    1 
ATOM   2275 C  CA   A MET A 1 171 ? 25.58449  -13.80479 -0.52953  0.507 29.30799  ? 151 MET A CA   1 
ATOM   2276 C  CA   B MET A 1 171 ? 25.58980  -13.80019 -0.52588  0.493 29.30874  ? 151 MET A CA   1 
ATOM   2277 C  C    . MET A 1 171 ? 25.43260  -12.99340 -1.80667  1.000 27.35652  ? 151 MET A C    1 
ATOM   2278 O  O    . MET A 1 171 ? 24.91460  -11.86751 -1.79092  1.000 26.77132  ? 151 MET A O    1 
ATOM   2279 C  CB   A MET A 1 171 ? 27.04104  -13.83467 -0.07996  0.507 31.15751  ? 151 MET A CB   1 
ATOM   2280 C  CB   B MET A 1 171 ? 27.06088  -13.78877 -0.08710  0.493 31.14455  ? 151 MET A CB   1 
ATOM   2281 C  CG   A MET A 1 171 ? 27.58961  -12.51162 0.22346   0.507 33.52112  ? 151 MET A CG   1 
ATOM   2282 C  CG   B MET A 1 171 ? 27.33032  -14.49313 1.22657   0.493 33.48832  ? 151 MET A CG   1 
ATOM   2283 S  SD   A MET A 1 171 ? 29.27477  -12.70578 0.78499   0.507 32.71240  ? 151 MET A SD   1 
ATOM   2284 S  SD   B MET A 1 171 ? 29.09334  -14.61304 1.60173   0.493 32.95569  ? 151 MET A SD   1 
ATOM   2285 C  CE   A MET A 1 171 ? 29.23169  -14.10348 1.89384   0.507 36.83617  ? 151 MET A CE   1 
ATOM   2286 C  CE   B MET A 1 171 ? 29.54424  -12.87795 1.56775   0.493 32.60184  ? 151 MET A CE   1 
ATOM   2287 H  H    A MET A 1 171 ? 25.73550  -15.77022 -0.60894  0.507 33.53341  ? 151 MET A H    1 
ATOM   2288 H  H    B MET A 1 171 ? 25.73514  -15.77083 -0.61026  0.493 33.53341  ? 151 MET A H    1 
ATOM   2289 H  HA   A MET A 1 171 ? 25.05378  -13.38139 0.16327   0.507 35.19335  ? 151 MET A HA   1 
ATOM   2290 H  HA   B MET A 1 171 ? 25.06042  -13.40007 0.18163   0.493 35.19425  ? 151 MET A HA   1 
ATOM   2291 H  HB2  A MET A 1 171 ? 27.10896  -14.37506 0.72271   0.507 37.41278  ? 151 MET A HB2  1 
ATOM   2292 H  HB2  B MET A 1 171 ? 27.59027  -14.22975 -0.76988  0.493 37.39722  ? 151 MET A HB2  1 
ATOM   2293 H  HB3  A MET A 1 171 ? 27.57834  -14.22323 -0.78794  0.507 37.41278  ? 151 MET A HB3  1 
ATOM   2294 H  HB3  B MET A 1 171 ? 27.34689  -12.86707 0.01067   0.493 37.39722  ? 151 MET A HB3  1 
ATOM   2295 H  HG2  A MET A 1 171 ? 27.58276  -11.95904 -0.57372  0.507 40.24910  ? 151 MET A HG2  1 
ATOM   2296 H  HG2  B MET A 1 171 ? 26.90327  -13.99933 1.94399   0.493 40.20975  ? 151 MET A HG2  1 
ATOM   2297 H  HG3  A MET A 1 171 ? 27.06858  -12.08939 0.92429   0.507 40.24910  ? 151 MET A HG3  1 
ATOM   2298 H  HG3  B MET A 1 171 ? 26.97042  -15.39284 1.18305   0.493 40.20975  ? 151 MET A HG3  1 
ATOM   2299 H  HE1  A MET A 1 171 ? 30.04094  -14.10739 2.42863   0.507 44.22717  ? 151 MET A HE1  1 
ATOM   2300 H  HE1  B MET A 1 171 ? 30.43248  -12.77507 1.94372   0.493 39.14597  ? 151 MET A HE1  1 
ATOM   2301 H  HE2  A MET A 1 171 ? 28.45501  -14.02590 2.46974   0.507 44.22717  ? 151 MET A HE2  1 
ATOM   2302 H  HE2  B MET A 1 171 ? 29.53601  -12.56746 0.64883   0.493 39.14597  ? 151 MET A HE2  1 
ATOM   2303 H  HE3  A MET A 1 171 ? 29.17624  -14.91915 1.37182   0.507 44.22717  ? 151 MET A HE3  1 
ATOM   2304 H  HE3  B MET A 1 171 ? 28.90249  -12.37455 2.09276   0.493 39.14597  ? 151 MET A HE3  1 
ATOM   2305 N  N    . PHE A 1 172 ? 25.87148  -13.55896 -2.93652  1.000 27.01575  ? 152 PHE A N    1 
ATOM   2306 C  CA   . PHE A 1 172 ? 25.78769  -12.82368 -4.18609  1.000 24.58903  ? 152 PHE A CA   1 
ATOM   2307 C  C    . PHE A 1 172 ? 24.34685  -12.65030 -4.62417  1.000 24.84331  ? 152 PHE A C    1 
ATOM   2308 O  O    . PHE A 1 172 ? 23.99550  -11.61878 -5.20414  1.000 24.36854  ? 152 PHE A O    1 
ATOM   2309 C  CB   . PHE A 1 172 ? 26.56856  -13.54037 -5.27727  1.000 25.98188  ? 152 PHE A CB   1 
ATOM   2310 C  CG   . PHE A 1 172 ? 28.04795  -13.23494 -5.26841  1.000 28.53878  ? 152 PHE A CG   1 
ATOM   2311 C  CD1  . PHE A 1 172 ? 28.86294  -13.72526 -4.27838  1.000 29.43325  ? 152 PHE A CD1  1 
ATOM   2312 C  CD2  . PHE A 1 172 ? 28.59764  -12.45375 -6.26511  1.000 32.48933  ? 152 PHE A CD2  1 
ATOM   2313 C  CE1  . PHE A 1 172 ? 30.21149  -13.44048 -4.26737  1.000 31.75954  ? 152 PHE A CE1  1 
ATOM   2314 C  CE2  . PHE A 1 172 ? 29.94430  -12.19110 -6.28443  1.000 32.28396  ? 152 PHE A CE2  1 
ATOM   2315 C  CZ   . PHE A 1 172 ? 30.75460  -12.69087 -5.29114  1.000 32.39809  ? 152 PHE A CZ   1 
ATOM   2316 H  H    . PHE A 1 172 ? 26.21186  -14.34631 -2.99822  1.000 32.44266  ? 152 PHE A H    1 
ATOM   2317 H  HA   . PHE A 1 172 ? 26.18465  -11.94827 -4.05582  1.000 29.53060  ? 152 PHE A HA   1 
ATOM   2318 H  HB2  . PHE A 1 172 ? 26.46323  -14.49732 -5.15878  1.000 31.20202  ? 152 PHE A HB2  1 
ATOM   2319 H  HB3  . PHE A 1 172 ? 26.21616  -13.27216 -6.14027  1.000 31.20202  ? 152 PHE A HB3  1 
ATOM   2320 H  HD1  . PHE A 1 172 ? 28.50046  -14.25640 -3.60651  1.000 35.34367  ? 152 PHE A HD1  1 
ATOM   2321 H  HD2  . PHE A 1 172 ? 28.05014  -12.10225 -6.92963  1.000 39.01096  ? 152 PHE A HD2  1 
ATOM   2322 H  HE1  . PHE A 1 172 ? 30.75075  -13.75073 -3.57611  1.000 38.13521  ? 152 PHE A HE1  1 
ATOM   2323 H  HE2  . PHE A 1 172 ? 30.30868  -11.67614 -6.96777  1.000 38.76452  ? 152 PHE A HE2  1 
ATOM   2324 H  HZ   . PHE A 1 172 ? 31.66922  -12.52343 -5.30958  1.000 38.90146  ? 152 PHE A HZ   1 
ATOM   2325 N  N    . LEU A 1 173 ? 23.49241  -13.63496 -4.34112  1.000 23.35656  ? 153 LEU A N    1 
ATOM   2326 C  CA   . LEU A 1 173 ? 22.08944  -13.49034 -4.73388  1.000 25.10448  ? 153 LEU A CA   1 
ATOM   2327 C  C    . LEU A 1 173 ? 21.41595  -12.38631 -3.92300  1.000 26.14220  ? 153 LEU A C    1 
ATOM   2328 O  O    . LEU A 1 173 ? 20.56040  -11.66854 -4.46419  1.000 26.65204  ? 153 LEU A O    1 
ATOM   2329 C  CB   . LEU A 1 173 ? 21.34812  -14.81280 -4.55950  1.000 26.96220  ? 153 LEU A CB   1 
ATOM   2330 C  CG   . LEU A 1 173 ? 19.97979  -14.91816 -5.25103  1.000 27.10834  ? 153 LEU A CG   1 
ATOM   2331 C  CD1  . LEU A 1 173 ? 20.04981  -14.58634 -6.70977  1.000 25.08141  ? 153 LEU A CD1  1 
ATOM   2332 C  CD2  . LEU A 1 173 ? 19.42827  -16.33608 -5.01042  1.000 34.78614  ? 153 LEU A CD2  1 
ATOM   2333 H  H    . LEU A 1 173 ? 23.69064  -14.36854 -3.93843  1.000 28.05163  ? 153 LEU A H    1 
ATOM   2334 H  HA   . LEU A 1 173 ? 22.04765  -13.25376 -5.67366  1.000 30.14914  ? 153 LEU A HA   1 
ATOM   2335 H  HB2  . LEU A 1 173 ? 21.90571  -15.52095 -4.91800  1.000 32.37840  ? 153 LEU A HB2  1 
ATOM   2336 H  HB3  . LEU A 1 173 ? 21.20156  -14.95391 -3.61108  1.000 32.37840  ? 153 LEU A HB3  1 
ATOM   2337 H  HG   . LEU A 1 173 ? 19.36969  -14.26495 -4.87423  1.000 32.55377  ? 153 LEU A HG   1 
ATOM   2338 H  HD11 . LEU A 1 173 ? 19.22922  -14.87491 -7.13903  1.000 30.12146  ? 153 LEU A HD11 1 
ATOM   2339 H  HD12 . LEU A 1 173 ? 20.15646  -13.62752 -6.81077  1.000 30.12146  ? 153 LEU A HD12 1 
ATOM   2340 H  HD13 . LEU A 1 173 ? 20.80804  -15.04667 -7.10232  1.000 30.12146  ? 153 LEU A HD13 1 
ATOM   2341 H  HD21 . LEU A 1 173 ? 18.56103  -16.41434 -5.43782  1.000 41.76713  ? 153 LEU A HD21 1 
ATOM   2342 H  HD22 . LEU A 1 173 ? 20.04359  -16.98286 -5.38983  1.000 41.76713  ? 153 LEU A HD22 1 
ATOM   2343 H  HD23 . LEU A 1 173 ? 19.34097  -16.48316 -4.05562  1.000 41.76713  ? 153 LEU A HD23 1 
ATOM   2344 N  N    . ARG A 1 174 ? 21.77505  -12.24208 -2.64227  1.000 25.38257  ? 154 ARG A N    1 
ATOM   2345 C  CA   . ARG A 1 174 ? 21.23570  -11.15175 -1.82003  1.000 27.42788  ? 154 ARG A CA   1 
ATOM   2346 C  C    . ARG A 1 174 ? 21.66314  -9.79012  -2.35258  1.000 27.36665  ? 154 ARG A C    1 
ATOM   2347 O  O    . ARG A 1 174 ? 20.81921  -8.88793  -2.51296  1.000 28.22750  ? 154 ARG A O    1 
ATOM   2348 C  CB   . ARG A 1 174 ? 21.65733  -11.32994 -0.36231  1.000 33.66077  ? 154 ARG A CB   1 
ATOM   2349 C  CG   . ARG A 1 174 ? 20.50428  -11.18578 0.59743   1.000 53.86011  ? 154 ARG A CG   1 
ATOM   2350 C  CD   . ARG A 1 174 ? 20.38869  -9.79164  1.14771   1.000 63.82743  ? 154 ARG A CD   1 
ATOM   2351 N  NE   . ARG A 1 174 ? 19.28472  -9.69263  2.09766   1.000 76.99609  ? 154 ARG A NE   1 
ATOM   2352 C  CZ   . ARG A 1 174 ? 18.69003  -8.55798  2.44114   1.000 83.54505  ? 154 ARG A CZ   1 
ATOM   2353 N  NH1  . ARG A 1 174 ? 19.09009  -7.39061  1.95629   1.000 72.94374  ? 154 ARG A NH1  1 
ATOM   2354 N  NH2  . ARG A 1 174 ? 17.66041  -8.59578  3.28328   1.000 86.96867  ? 154 ARG A NH2  1 
ATOM   2355 H  H    . ARG A 1 174 ? 22.32487  -12.75729 -2.22771  1.000 30.48285  ? 154 ARG A H    1 
ATOM   2356 H  HA   . ARG A 1 174 ? 20.26700  -11.18917 -1.85338  1.000 32.93722  ? 154 ARG A HA   1 
ATOM   2357 H  HB2  . ARG A 1 174 ? 22.03440  -12.21638 -0.24849  1.000 40.41669  ? 154 ARG A HB2  1 
ATOM   2358 H  HB3  . ARG A 1 174 ? 22.31946  -10.65675 -0.14029  1.000 40.41669  ? 154 ARG A HB3  1 
ATOM   2359 H  HG2  . ARG A 1 174 ? 19.67782  -11.39670 0.13550   1.000 64.65589  ? 154 ARG A HG2  1 
ATOM   2360 H  HG3  . ARG A 1 174 ? 20.63256  -11.79384 1.34221   1.000 64.65589  ? 154 ARG A HG3  1 
ATOM   2361 H  HD2  . ARG A 1 174 ? 21.21039  -9.55653  1.60645   1.000 76.61667  ? 154 ARG A HD2  1 
ATOM   2362 H  HD3  . ARG A 1 174 ? 20.22498  -9.17033  0.42102   1.000 76.61667  ? 154 ARG A HD3  1 
ATOM   2363 H  HE   . ARG A 1 174 ? 19.00064  -10.41942 2.45914   1.000 92.41907  ? 154 ARG A HE   1 
ATOM   2364 H  HH11 . ARG A 1 174 ? 19.74969  -7.35705  1.40547   1.000 87.55625  ? 154 ARG A HH11 1 
ATOM   2365 H  HH12 . ARG A 1 174 ? 18.68999  -6.66696  2.19261   1.000 87.55625  ? 154 ARG A HH12 1 
ATOM   2366 H  HH21 . ARG A 1 174 ? 17.38901  -9.34907  3.59711   1.000 104.38617 ? 154 ARG A HH21 1 
ATOM   2367 H  HH22 . ARG A 1 174 ? 17.26638  -7.86691  3.51371   1.000 104.38617 ? 154 ARG A HH22 1 
ATOM   2368 N  N    . TRP A 1 175 ? 22.95281  -9.62894  -2.67640  1.000 25.79636  ? 155 TRP A N    1 
ATOM   2369 C  CA   . TRP A 1 175 ? 23.39674  -8.37759  -3.30277  1.000 26.34744  ? 155 TRP A CA   1 
ATOM   2370 C  C    . TRP A 1 175 ? 22.63339  -8.10001  -4.59505  1.000 24.58528  ? 155 TRP A C    1 
ATOM   2371 O  O    . TRP A 1 175 ? 22.29481  -6.94721  -4.88767  1.000 25.44685  ? 155 TRP A O    1 
ATOM   2372 C  CB   . TRP A 1 175 ? 24.89092  -8.39148  -3.62741  1.000 27.00612  ? 155 TRP A CB   1 
ATOM   2373 C  CG   . TRP A 1 175 ? 25.78217  -8.62145  -2.49203  1.000 26.80363  ? 155 TRP A CG   1 
ATOM   2374 C  CD1  . TRP A 1 175 ? 25.50911  -8.43562  -1.16942  1.000 28.72074  ? 155 TRP A CD1  1 
ATOM   2375 C  CD2  . TRP A 1 175 ? 27.12180  -9.11857  -2.57051  1.000 25.01600  ? 155 TRP A CD2  1 
ATOM   2376 N  NE1  . TRP A 1 175 ? 26.62832  -8.77366  -0.40775  1.000 31.38077  ? 155 TRP A NE1  1 
ATOM   2377 C  CE2  . TRP A 1 175 ? 27.61894  -9.20494  -1.25639  1.000 31.67798  ? 155 TRP A CE2  1 
ATOM   2378 C  CE3  . TRP A 1 175 ? 27.94517  -9.47963  -3.63315  1.000 27.79953  ? 155 TRP A CE3  1 
ATOM   2379 C  CZ2  . TRP A 1 175 ? 28.90037  -9.64684  -0.98509  1.000 36.50419  ? 155 TRP A CZ2  1 
ATOM   2380 C  CZ3  . TRP A 1 175 ? 29.22039  -9.93954  -3.36223  1.000 35.62431  ? 155 TRP A CZ3  1 
ATOM   2381 C  CH2  . TRP A 1 175 ? 29.67869  -10.02052 -2.04473  1.000 31.93755  ? 155 TRP A CH2  1 
ATOM   2382 H  H    . TRP A 1 175 ? 23.57270  -10.21106 -2.54804  1.000 30.97940  ? 155 TRP A H    1 
ATOM   2383 H  HA   . TRP A 1 175 ? 23.23161  -7.67466  -2.65507  1.000 31.64070  ? 155 TRP A HA   1 
ATOM   2384 H  HB2  . TRP A 1 175 ? 25.05632  -9.09800  -4.27112  1.000 32.43110  ? 155 TRP A HB2  1 
ATOM   2385 H  HB3  . TRP A 1 175 ? 25.12763  -7.53209  -4.00991  1.000 32.43110  ? 155 TRP A HB3  1 
ATOM   2386 H  HD1  . TRP A 1 175 ? 24.70022  -8.13013  -0.82699  1.000 34.48866  ? 155 TRP A HD1  1 
ATOM   2387 H  HE1  . TRP A 1 175 ? 26.68797  -8.72092  0.44855   1.000 37.68068  ? 155 TRP A HE1  1 
ATOM   2388 H  HE3  . TRP A 1 175 ? 27.64270  -9.41265  -4.51003  1.000 33.38320  ? 155 TRP A HE3  1 
ATOM   2389 H  HZ2  . TRP A 1 175 ? 29.22127  -9.68837  -0.11319  1.000 43.82879  ? 155 TRP A HZ2  1 
ATOM   2390 H  HZ3  . TRP A 1 175 ? 29.77694  -10.19674 -4.06152  1.000 42.77294  ? 155 TRP A HZ3  1 
ATOM   2391 H  HH2  . TRP A 1 175 ? 30.53802  -10.33781 -1.88420  1.000 38.34882  ? 155 TRP A HH2  1 
ATOM   2392 N  N    . SER A 1 176 ? 22.43110  -9.14131  -5.41186  1.000 23.94333  ? 156 SER A N    1 
ATOM   2393 C  CA   . SER A 1 176 ? 21.73699  -9.00434  -6.67908  1.000 25.40807  ? 156 SER A CA   1 
ATOM   2394 C  C    . SER A 1 176 ? 20.30380  -8.56845  -6.46932  1.000 25.29879  ? 156 SER A C    1 
ATOM   2395 O  O    . SER A 1 176 ? 19.79424  -7.71607  -7.20850  1.000 25.69341  ? 156 SER A O    1 
ATOM   2396 C  CB   . SER A 1 176 ? 21.78850  -10.32372 -7.43094  1.000 22.69249  ? 156 SER A CB   1 
ATOM   2397 O  OG   . SER A 1 176 ? 23.14903  -10.65046 -7.70117  1.000 23.36181  ? 156 SER A OG   1 
ATOM   2398 H  H    . SER A 1 176 ? 22.69171  -9.94413  -5.24707  1.000 28.75576  ? 156 SER A H    1 
ATOM   2399 H  HA   . SER A 1 176 ? 22.18009  -8.32863  -7.21572  1.000 30.51345  ? 156 SER A HA   1 
ATOM   2400 H  HB2  . SER A 1 176 ? 21.39051  -11.02136 -6.88706  1.000 27.25475  ? 156 SER A HB2  1 
ATOM   2401 H  HB3  . SER A 1 176 ? 21.30445  -10.23824 -8.26718  1.000 27.25475  ? 156 SER A HB3  1 
ATOM   2402 H  HG   . SER A 1 176 ? 23.19848  -11.41761 -8.03976  1.000 28.05794  ? 156 SER A HG   1 
ATOM   2403 N  N    . ASP A 1 177 ? 19.64134  -9.15536  -5.46104  1.000 24.90838  ? 157 ASP A N    1 
ATOM   2404 C  CA   . ASP A 1 177 ? 18.25909  -8.79567  -5.15714  1.000 25.52245  ? 157 ASP A CA   1 
ATOM   2405 C  C    . ASP A 1 177 ? 18.19057  -7.32308  -4.75707  1.000 27.38305  ? 157 ASP A C    1 
ATOM   2406 O  O    . ASP A 1 177 ? 17.27614  -6.59216  -5.16927  1.000 27.56226  ? 157 ASP A O    1 
ATOM   2407 C  CB   . ASP A 1 177 ? 17.71846  -9.67411  -4.01939  1.000 30.33223  ? 157 ASP A CB   1 
ATOM   2408 C  CG   . ASP A 1 177 ? 17.50053  -11.18722 -4.38243  1.000 39.40692  ? 157 ASP A CG   1 
ATOM   2409 O  OD1  . ASP A 1 177 ? 17.40755  -11.63915 -5.55557  1.000 32.63751  ? 157 ASP A OD1  1 
ATOM   2410 O  OD2  . ASP A 1 177 ? 17.34141  -11.96776 -3.39827  1.000 37.93426  ? 157 ASP A OD2  1 
ATOM   2411 H  H    . ASP A 1 177 ? 19.97064  -9.75920  -4.94477  1.000 29.91381  ? 157 ASP A H    1 
ATOM   2412 H  HA   . ASP A 1 177 ? 17.70405  -8.94817  -5.93789  1.000 30.65071  ? 157 ASP A HA   1 
ATOM   2413 H  HB2  . ASP A 1 177 ? 18.34812  -9.64183  -3.28225  1.000 36.42243  ? 157 ASP A HB2  1 
ATOM   2414 H  HB3  . ASP A 1 177 ? 16.86085  -9.31804  -3.73897  1.000 36.42243  ? 157 ASP A HB3  1 
ATOM   2415 N  N    . ASP A 1 178 ? 19.16079  -6.86930  -3.96213  1.000 24.71514  ? 158 ASP A N    1 
ATOM   2416 C  CA   . ASP A 1 178 ? 19.20437  -5.47112  -3.53833  1.000 30.16170  ? 158 ASP A CA   1 
ATOM   2417 C  C    . ASP A 1 178 ? 19.38059  -4.54904  -4.73863  1.000 32.53113  ? 158 ASP A C    1 
ATOM   2418 O  O    . ASP A 1 178 ? 18.71979  -3.50542  -4.84673  1.000 29.18335  ? 158 ASP A O    1 
ATOM   2419 C  CB   . ASP A 1 178 ? 20.33686  -5.22781  -2.52674  1.000 27.75031  ? 158 ASP A CB   1 
ATOM   2420 C  CG   . ASP A 1 178 ? 20.12527  -5.92872  -1.18627  1.000 34.58011  ? 158 ASP A CG   1 
ATOM   2421 O  OD1  . ASP A 1 178 ? 18.97843  -6.25427  -0.83367  1.000 39.73739  ? 158 ASP A OD1  1 
ATOM   2422 O  OD2  . ASP A 1 178 ? 21.13273  -6.11844  -0.47606  1.000 42.36390  ? 158 ASP A OD2  1 
ATOM   2423 H  H    . ASP A 1 178 ? 19.80458  -7.34955  -3.65473  1.000 29.68193  ? 158 ASP A H    1 
ATOM   2424 H  HA   . ASP A 1 178 ? 18.36506  -5.26909  -3.09600  1.000 36.21780  ? 158 ASP A HA   1 
ATOM   2425 H  HB2  . ASP A 1 178 ? 21.16825  -5.55562  -2.90389  1.000 33.32413  ? 158 ASP A HB2  1 
ATOM   2426 H  HB3  . ASP A 1 178 ? 20.40313  -4.27539  -2.35524  1.000 33.32413  ? 158 ASP A HB3  1 
ATOM   2427 N  N    . LEU A 1 179 ? 20.32568  -4.88371  -5.61876  1.000 27.02718  ? 159 LEU A N    1 
ATOM   2428 C  CA   . LEU A 1 179 ? 20.60534  -4.04217  -6.78139  1.000 26.55953  ? 159 LEU A CA   1 
ATOM   2429 C  C    . LEU A 1 179 ? 19.42519  -3.98469  -7.74884  1.000 28.44448  ? 159 LEU A C    1 
ATOM   2430 O  O    . LEU A 1 179 ? 19.08041  -2.90348  -8.23307  1.000 29.67666  ? 159 LEU A O    1 
ATOM   2431 C  CB   . LEU A 1 179 ? 21.86879  -4.55721  -7.49512  1.000 27.97623  ? 159 LEU A CB   1 
ATOM   2432 C  CG   . LEU A 1 179 ? 23.12018  -4.36602  -6.63782  1.000 32.66050  ? 159 LEU A CG   1 
ATOM   2433 C  CD1  . LEU A 1 179 ? 24.32136  -5.21978  -7.08201  1.000 34.82053  ? 159 LEU A CD1  1 
ATOM   2434 C  CD2  . LEU A 1 179 ? 23.49526  -2.90197  -6.60121  1.000 34.15116  ? 159 LEU A CD2  1 
ATOM   2435 H  H    . LEU A 1 179 ? 20.81618  -5.58818  -5.56644  1.000 32.45638  ? 159 LEU A H    1 
ATOM   2436 H  HA   . LEU A 1 179 ? 20.76787  -3.13612  -6.47552  1.000 31.89520  ? 159 LEU A HA   1 
ATOM   2437 H  HB2  . LEU A 1 179 ? 21.76714  -5.50393  -7.68030  1.000 33.59524  ? 159 LEU A HB2  1 
ATOM   2438 H  HB3  . LEU A 1 179 ? 21.98881  -4.06803  -8.32409  1.000 33.59524  ? 159 LEU A HB3  1 
ATOM   2439 H  HG   . LEU A 1 179 ? 22.90328  -4.67511  -5.74434  1.000 39.21636  ? 159 LEU A HG   1 
ATOM   2440 H  HD11 . LEU A 1 179 ? 25.02414  -5.14606  -6.41751  1.000 41.80839  ? 159 LEU A HD11 1 
ATOM   2441 H  HD12 . LEU A 1 179 ? 24.03886  -6.14414  -7.16355  1.000 41.80839  ? 159 LEU A HD12 1 
ATOM   2442 H  HD13 . LEU A 1 179 ? 24.64044  -4.89464  -7.93838  1.000 41.80839  ? 159 LEU A HD13 1 
ATOM   2443 H  HD21 . LEU A 1 179 ? 24.41388  -2.81872  -6.30104  1.000 41.00515  ? 159 LEU A HD21 1 
ATOM   2444 H  HD22 . LEU A 1 179 ? 23.40349  -2.53007  -7.49238  1.000 41.00515  ? 159 LEU A HD22 1 
ATOM   2445 H  HD23 . LEU A 1 179 ? 22.90347  -2.43961  -5.98728  1.000 41.00515  ? 159 LEU A HD23 1 
ATOM   2446 N  N    . VAL A 1 180 ? 18.78372  -5.11563  -8.03894  1.000 26.41347  ? 160 VAL A N    1 
ATOM   2447 C  CA   . VAL A 1 180 ? 17.64893  -5.08047  -8.97377  1.000 26.98667  ? 160 VAL A CA   1 
ATOM   2448 C  C    . VAL A 1 180 ? 16.46184  -4.39380  -8.31487  1.000 27.64299  ? 160 VAL A C    1 
ATOM   2449 O  O    . VAL A 1 180 ? 15.67245  -3.73611  -8.99378  1.000 29.30876  ? 160 VAL A O    1 
ATOM   2450 C  CB   . VAL A 1 180 ? 17.30163  -6.49073  -9.46663  1.000 27.19759  ? 160 VAL A CB   1 
ATOM   2451 C  CG1  . VAL A 1 180 ? 16.48107  -7.23416  -8.45032  1.000 27.33148  ? 160 VAL A CG1  1 
ATOM   2452 C  CG2  . VAL A 1 180 ? 16.57386  -6.44149  -10.84738 1.000 31.93937  ? 160 VAL A CG2  1 
ATOM   2453 H  H    . VAL A 1 180 ? 18.97474  -5.89196  -7.72202  1.000 31.71993  ? 160 VAL A H    1 
ATOM   2454 H  HA   . VAL A 1 180 ? 17.90184  -4.56634  -9.75646  1.000 32.40776  ? 160 VAL A HA   1 
ATOM   2455 H  HB   . VAL A 1 180 ? 18.13037  -6.97979  -9.58876  1.000 32.66088  ? 160 VAL A HB   1 
ATOM   2456 H  HG11 . VAL A 1 180 ? 16.47856  -8.17766  -8.67549  1.000 32.82154  ? 160 VAL A HG11 1 
ATOM   2457 H  HG12 . VAL A 1 180 ? 16.87267  -7.10465  -7.57239  1.000 32.82154  ? 160 VAL A HG12 1 
ATOM   2458 H  HG13 . VAL A 1 180 ? 15.57471  -6.88879  -8.46245  1.000 32.82154  ? 160 VAL A HG13 1 
ATOM   2459 H  HG21 . VAL A 1 180 ? 16.36949  -7.34689  -11.12911 1.000 38.35100  ? 160 VAL A HG21 1 
ATOM   2460 H  HG22 . VAL A 1 180 ? 15.75428  -5.93106  -10.75434 1.000 38.35100  ? 160 VAL A HG22 1 
ATOM   2461 H  HG23 . VAL A 1 180 ? 17.15627  -6.01663  -11.49637 1.000 38.35100  ? 160 VAL A HG23 1 
ATOM   2462 N  N    . THR A 1 181 ? 16.33303  -4.49048  -6.99094  1.000 27.36722  ? 161 THR A N    1 
ATOM   2463 C  CA   . THR A 1 181 ? 15.27741  -3.74236  -6.30338  1.000 28.77885  ? 161 THR A CA   1 
ATOM   2464 C  C    . THR A 1 181 ? 15.50051  -2.23214  -6.42009  1.000 30.03480  ? 161 THR A C    1 
ATOM   2465 O  O    . THR A 1 181 ? 14.53697  -1.47013  -6.58409  1.000 29.64932  ? 161 THR A O    1 
ATOM   2466 C  CB   . THR A 1 181 ? 15.17620  -4.18282  -4.84396  1.000 30.88387  ? 161 THR A CB   1 
ATOM   2467 O  OG1  . THR A 1 181 ? 14.71330  -5.54262  -4.79399  1.000 34.49536  ? 161 THR A OG1  1 
ATOM   2468 C  CG2  . THR A 1 181 ? 14.15613  -3.31047  -4.12579  1.000 33.66002  ? 161 THR A CG2  1 
ATOM   2469 H  H    . THR A 1 181 ? 16.83044  -4.96977  -6.47863  1.000 32.86442  ? 161 THR A H    1 
ATOM   2470 H  HA   . THR A 1 181 ? 14.42610  -3.94436  -6.72215  1.000 34.55838  ? 161 THR A HA   1 
ATOM   2471 H  HB   . THR A 1 181 ? 16.04061  -4.10682  -4.41046  1.000 37.08441  ? 161 THR A HB   1 
ATOM   2472 H  HG1  . THR A 1 181 ? 15.21182  -6.03310  -5.25930  1.000 41.41819  ? 161 THR A HG1  1 
ATOM   2473 H  HG21 . THR A 1 181 ? 13.86995  -3.74162  -3.30535  1.000 40.41579  ? 161 THR A HG21 1 
ATOM   2474 H  HG22 . THR A 1 181 ? 14.54907  -2.45053  -3.90901  1.000 40.41579  ? 161 THR A HG22 1 
ATOM   2475 H  HG23 . THR A 1 181 ? 13.38243  -3.16892  -4.69346  1.000 40.41579  ? 161 THR A HG23 1 
ATOM   2476 N  N    . PHE A 1 182 ? 16.76169  -1.77810  -6.37103  1.000 28.56358  ? 162 PHE A N    1 
ATOM   2477 C  CA   . PHE A 1 182 ? 17.07473  -0.36896  -6.56930  1.000 27.60067  ? 162 PHE A CA   1 
ATOM   2478 C  C    . PHE A 1 182 ? 16.61629  0.09912   -7.94781  1.000 30.37105  ? 162 PHE A C    1 
ATOM   2479 O  O    . PHE A 1 182 ? 16.11607  1.22047   -8.10144  1.000 33.07420  ? 162 PHE A O    1 
ATOM   2480 C  CB   . PHE A 1 182 ? 18.58145  -0.14898  -6.41321  1.000 29.86528  ? 162 PHE A CB   1 
ATOM   2481 C  CG   . PHE A 1 182 ? 19.02559  1.25135   -6.70819  1.000 31.15488  ? 162 PHE A CG   1 
ATOM   2482 C  CD1  . PHE A 1 182 ? 18.96349  2.22716   -5.73686  1.000 35.68596  ? 162 PHE A CD1  1 
ATOM   2483 C  CD2  . PHE A 1 182 ? 19.49456  1.58209   -7.96187  1.000 37.92701  ? 162 PHE A CD2  1 
ATOM   2484 C  CE1  . PHE A 1 182 ? 19.36869  3.52512   -6.01613  1.000 42.56601  ? 162 PHE A CE1  1 
ATOM   2485 C  CE2  . PHE A 1 182 ? 19.88252  2.86404   -8.25414  1.000 40.45922  ? 162 PHE A CE2  1 
ATOM   2486 C  CZ   . PHE A 1 182 ? 19.82565  3.84039   -7.27583  1.000 42.22041  ? 162 PHE A CZ   1 
ATOM   2487 H  H    . PHE A 1 182 ? 17.45110  -2.27073  -6.22396  1.000 34.30006  ? 162 PHE A H    1 
ATOM   2488 H  HA   . PHE A 1 182 ? 16.61543  0.15757   -5.89647  1.000 33.14457  ? 162 PHE A HA   1 
ATOM   2489 H  HB2  . PHE A 1 182 ? 18.83236  -0.35175  -5.49843  1.000 35.86210  ? 162 PHE A HB2  1 
ATOM   2490 H  HB3  . PHE A 1 182 ? 19.04727  -0.74127  -7.02404  1.000 35.86210  ? 162 PHE A HB3  1 
ATOM   2491 H  HD1  . PHE A 1 182 ? 18.64788  2.01450   -4.88829  1.000 42.84692  ? 162 PHE A HD1  1 
ATOM   2492 H  HD2  . PHE A 1 182 ? 19.54849  0.92597   -8.61876  1.000 45.53618  ? 162 PHE A HD2  1 
ATOM   2493 H  HE1  . PHE A 1 182 ? 19.33163  4.17856   -5.35542  1.000 51.10297  ? 162 PHE A HE1  1 
ATOM   2494 H  HE2  . PHE A 1 182 ? 20.18323  3.07680   -9.10808  1.000 48.57483  ? 162 PHE A HE2  1 
ATOM   2495 H  HZ   . PHE A 1 182 ? 20.09591  4.70904   -7.46897  1.000 50.68826  ? 162 PHE A HZ   1 
ATOM   2496 N  N    . LEU A 1 183 ? 16.82256  -0.73391  -8.96175  1.000 27.91261  ? 163 LEU A N    1 
ATOM   2497 C  CA   . LEU A 1 183 ? 16.41448  -0.41149  -10.32321 1.000 25.54592  ? 163 LEU A CA   1 
ATOM   2498 C  C    . LEU A 1 183 ? 14.91586  -0.53588  -10.52541 1.000 29.08081  ? 163 LEU A C    1 
ATOM   2499 O  O    . LEU A 1 183 ? 14.38423  0.02985   -11.50577 1.000 26.42707  ? 163 LEU A O    1 
ATOM   2500 C  CB   . LEU A 1 183 ? 17.10022  -1.35819  -11.30703 1.000 28.52414  ? 163 LEU A CB   1 
ATOM   2501 C  CG   . LEU A 1 183 ? 18.62036  -1.42093  -11.36122 1.000 29.41328  ? 163 LEU A CG   1 
ATOM   2502 C  CD1  . LEU A 1 183 ? 19.12365  -2.63333  -12.15327 1.000 30.20147  ? 163 LEU A CD1  1 
ATOM   2503 C  CD2  . LEU A 1 183 ? 19.11478  -0.13655  -11.96465 1.000 31.30792  ? 163 LEU A CD2  1 
ATOM   2504 H  H    . LEU A 1 183 ? 17.20170  -1.50225  -8.88765  1.000 33.51889  ? 163 LEU A H    1 
ATOM   2505 H  HA   . LEU A 1 183 ? 16.68334  0.50196   -10.50820 1.000 30.67886  ? 163 LEU A HA   1 
ATOM   2506 H  HB2  . LEU A 1 183 ? 16.79943  -2.25652  -11.09864 1.000 34.25273  ? 163 LEU A HB2  1 
ATOM   2507 H  HB3  . LEU A 1 183 ? 16.80764  -1.10858  -12.19754 1.000 34.25273  ? 163 LEU A HB3  1 
ATOM   2508 H  HG   . LEU A 1 183 ? 18.97711  -1.52809  -10.46559 1.000 35.31970  ? 163 LEU A HG   1 
ATOM   2509 H  HD11 . LEU A 1 183 ? 20.09294  -2.65151  -12.12082 1.000 36.26552  ? 163 LEU A HD11 1 
ATOM   2510 H  HD12 . LEU A 1 183 ? 18.76415  -3.44172  -11.75558 1.000 36.26552  ? 163 LEU A HD12 1 
ATOM   2511 H  HD13 . LEU A 1 183 ? 18.82487  -2.55595  -13.07286 1.000 36.26552  ? 163 LEU A HD13 1 
ATOM   2512 H  HD21 . LEU A 1 183 ? 20.07640  -0.19122  -12.07957 1.000 37.59327  ? 163 LEU A HD21 1 
ATOM   2513 H  HD22 . LEU A 1 183 ? 18.68575  -0.00600  -12.82476 1.000 37.59327  ? 163 LEU A HD22 1 
ATOM   2514 H  HD23 . LEU A 1 183 ? 18.89390  0.59732   -11.37005 1.000 37.59327  ? 163 LEU A HD23 1 
ATOM   2515 N  N    . SER A 1 184 ? 14.23893  -1.28301  -9.63964  1.000 30.07080  ? 164 SER A N    1 
ATOM   2516 C  CA   . SER A 1 184 ? 12.81053  -1.61586  -9.72679  1.000 30.09114  ? 164 SER A CA   1 
ATOM   2517 C  C    . SER A 1 184 ? 11.92537  -0.68884  -8.89260  1.000 29.13843  ? 164 SER A C    1 
ATOM   2518 O  O    . SER A 1 184 ? 10.71431  -0.94914  -8.74142  1.000 26.66230  ? 164 SER A O    1 
ATOM   2519 C  CB   . SER A 1 184 ? 12.58871  -3.07898  -9.27870  1.000 29.52097  ? 164 SER A CB   1 
ATOM   2520 O  OG   . SER A 1 184 ? 13.04683  -4.11606  -10.19169 1.000 28.69100  ? 164 SER A OG   1 
ATOM   2521 H  H    . SER A 1 184 ? 14.60674  -1.62641  -8.94222  1.000 36.10872  ? 164 SER A H    1 
ATOM   2522 H  HA   . SER A 1 184 ? 12.53550  -1.52783  -10.65280 1.000 36.13313  ? 164 SER A HA   1 
ATOM   2523 H  HB2  . SER A 1 184 ? 13.05693  -3.20162  -8.43809  1.000 35.44892  ? 164 SER A HB2  1 
ATOM   2524 H  HB3  . SER A 1 184 ? 11.63558  -3.20380  -9.14883  1.000 35.44892  ? 164 SER A HB3  1 
ATOM   2525 H  HG   . SER A 1 184 ? 13.88554  -4.10833  -10.23768 1.000 34.45296  ? 164 SER A HG   1 
ATOM   2526 N  N    . SER A 1 185 ? 12.49077  0.37710   -8.32281  1.000 29.69555  ? 165 SER A N    1 
ATOM   2527 C  CA   . SER A 1 185 ? 11.74812  1.20968   -7.39097  1.000 35.40760  ? 165 SER A CA   1 
ATOM   2528 C  C    . SER A 1 185 ? 12.45541  2.54581   -7.23036  1.000 44.92071  ? 165 SER A C    1 
ATOM   2529 O  O    . SER A 1 185 ? 13.44695  2.83719   -7.90436  1.000 44.08301  ? 165 SER A O    1 
ATOM   2530 C  CB   . SER A 1 185 ? 11.58447  0.50021   -6.04288  1.000 47.35999  ? 165 SER A CB   1 
ATOM   2531 O  OG   . SER A 1 185 ? 12.83510  0.35100   -5.36530  1.000 39.45746  ? 165 SER A OG   1 
ATOM   2532 H  H    . SER A 1 185 ? 13.29976  0.63317   -8.46264  1.000 35.65842  ? 165 SER A H    1 
ATOM   2533 H  HA   . SER A 1 185 ? 10.87183  1.38602   -7.76769  1.000 42.51288  ? 165 SER A HA   1 
ATOM   2534 H  HB2  . SER A 1 185 ? 10.98822  1.02402   -5.48520  1.000 56.85575  ? 165 SER A HB2  1 
ATOM   2535 H  HB3  . SER A 1 185 ? 11.20663  -0.37970  -6.19743  1.000 56.85575  ? 165 SER A HB3  1 
ATOM   2536 H  HG   . SER A 1 185 ? 13.40550  0.01884   -5.88483  1.000 47.37271  ? 165 SER A HG   1 
ATOM   2537 N  N    . HIS A 1 186 ? 11.90474  3.37286   -6.34927  1.000 46.18822  ? 166 HIS A N    1 
ATOM   2538 C  CA   . HIS A 1 186 ? 12.51717  4.63224   -5.92278  1.000 50.18257  ? 166 HIS A CA   1 
ATOM   2539 C  C    . HIS A 1 186 ? 12.83843  4.44399   -4.43927  1.000 54.81329  ? 166 HIS A C    1 
ATOM   2540 O  O    . HIS A 1 186 ? 11.94411  4.52377   -3.58829  1.000 59.15121  ? 166 HIS A O    1 
ATOM   2541 C  CB   . HIS A 1 186 ? 11.58524  5.81029   -6.18455  1.000 51.38677  ? 166 HIS A CB   1 
ATOM   2542 C  CG   . HIS A 1 186 ? 12.12169  7.12167   -5.69082  1.000 69.44911  ? 166 HIS A CG   1 
ATOM   2543 N  ND1  . HIS A 1 186 ? 11.68023  7.71216   -4.52482  1.000 68.57178  ? 166 HIS A ND1  1 
ATOM   2544 C  CD2  . HIS A 1 186 ? 13.06171  7.95416   -6.19925  1.000 69.35854  ? 166 HIS A CD2  1 
ATOM   2545 C  CE1  . HIS A 1 186 ? 12.32351  8.85101   -4.33695  1.000 69.95232  ? 166 HIS A CE1  1 
ATOM   2546 N  NE2  . HIS A 1 186 ? 13.16743  9.02186   -5.33876  1.000 69.44617  ? 166 HIS A NE2  1 
ATOM   2547 H  H    . HIS A 1 186 ? 11.14817  3.22284   -5.96889  1.000 55.44962  ? 166 HIS A H    1 
ATOM   2548 H  HA   . HIS A 1 186 ? 13.33633  4.81363   -6.40958  1.000 60.24285  ? 166 HIS A HA   1 
ATOM   2549 N  N    . VAL A 1 187 ? 14.12513  4.16983   -4.12655  1.000 54.11113  ? 167 VAL A N    1 
ATOM   2550 C  CA   . VAL A 1 187 ? 14.49161  3.65908   -2.80613  1.000 54.38607  ? 167 VAL A CA   1 
ATOM   2551 C  C    . VAL A 1 187 ? 14.49233  4.77200   -1.75980  1.000 58.26550  ? 167 VAL A C    1 
ATOM   2552 O  O    . VAL A 1 187 ? 14.71611  5.94813   -2.05714  1.000 50.28716  ? 167 VAL A O    1 
ATOM   2553 C  CB   . VAL A 1 187 ? 15.86568  2.94847   -2.84337  1.000 56.05318  ? 167 VAL A CB   1 
ATOM   2554 C  CG1  . VAL A 1 187 ? 15.83026  1.71716   -3.76541  1.000 47.28848  ? 167 VAL A CG1  1 
ATOM   2555 C  CG2  . VAL A 1 187 ? 16.97970  3.91023   -3.28253  1.000 56.05205  ? 167 VAL A CG2  1 
ATOM   2556 H  H    . VAL A 1 187 ? 14.78950  4.27340   -4.66273  1.000 64.95711  ? 167 VAL A H    1 
ATOM   2557 H  HA   . VAL A 1 187 ? 13.81047  3.01595   -2.55450  1.000 65.28704  ? 167 VAL A HA   1 
ATOM   2558 H  HB   . VAL A 1 187 ? 16.06610  2.64709   -1.94343  1.000 67.28758  ? 167 VAL A HB   1 
ATOM   2559 H  HG11 . VAL A 1 187 ? 16.72167  1.33880   -3.82139  1.000 56.76994  ? 167 VAL A HG11 1 
ATOM   2560 H  HG12 . VAL A 1 187 ? 15.21609  1.06354   -3.39597  1.000 56.76994  ? 167 VAL A HG12 1 
ATOM   2561 H  HG13 . VAL A 1 187 ? 15.53120  1.99098   -4.64660  1.000 56.76994  ? 167 VAL A HG13 1 
ATOM   2562 H  HG21 . VAL A 1 187 ? 17.84001  3.49568   -3.11249  1.000 67.28622  ? 167 VAL A HG21 1 
ATOM   2563 H  HG22 . VAL A 1 187 ? 16.88270  4.09429   -4.22996  1.000 67.28622  ? 167 VAL A HG22 1 
ATOM   2564 H  HG23 . VAL A 1 187 ? 16.90358  4.73399   -2.77605  1.000 67.28622  ? 167 VAL A HG23 1 
ATOM   2565 N  N    . SER A 1 188 ? 14.24834  4.38249   -0.50974  1.000 51.03488  ? 168 SER A N    1 
ATOM   2566 C  CA   . SER A 1 188 ? 14.44639  5.26338   0.63107   1.000 56.30848  ? 168 SER A CA   1 
ATOM   2567 C  C    . SER A 1 188 ? 15.94185  5.53076   0.82347   1.000 63.39163  ? 168 SER A C    1 
ATOM   2568 O  O    . SER A 1 188 ? 16.79682  5.04035   0.07732   1.000 58.68838  ? 168 SER A O    1 
ATOM   2569 C  CB   . SER A 1 188 ? 13.86835  4.63751   1.89697   1.000 55.05438  ? 168 SER A CB   1 
ATOM   2570 O  OG   . SER A 1 188 ? 14.51116  3.40832   2.19997   1.000 53.84301  ? 168 SER A OG   1 
ATOM   2571 H  H    . SER A 1 188 ? 13.96298  3.60008   -0.29528  1.000 61.26562  ? 168 SER A H    1 
ATOM   2572 H  HA   . SER A 1 188 ? 13.98677  6.10001   0.45871   1.000 67.59394  ? 168 SER A HA   1 
ATOM   2573 H  HB2  . SER A 1 188 ? 13.99650  5.25049   2.63773   1.000 66.08902  ? 168 SER A HB2  1 
ATOM   2574 H  HB3  . SER A 1 188 ? 12.92193  4.47281   1.76256   1.000 66.08902  ? 168 SER A HB3  1 
ATOM   2575 H  HG   . SER A 1 188 ? 15.10457  3.53023   2.78187   1.000 64.63537  ? 168 SER A HG   1 
ATOM   2576 N  N    . GLN A 1 189 ? 16.27213  6.30462   1.85805   1.000 55.19991  ? 169 GLN A N    1 
ATOM   2577 C  CA   . GLN A 1 189 ? 17.68117  6.57200   2.12369   1.000 57.26217  ? 169 GLN A CA   1 
ATOM   2578 C  C    . GLN A 1 189 ? 18.36867  5.32129   2.65998   1.000 58.12590  ? 169 GLN A C    1 
ATOM   2579 O  O    . GLN A 1 189 ? 19.50142  5.00953   2.26645   1.000 54.35162  ? 169 GLN A O    1 
ATOM   2580 C  CB   . GLN A 1 189 ? 17.82710  7.73445   3.10636   1.000 56.21866  ? 169 GLN A CB   1 
ATOM   2581 C  CG   . GLN A 1 189 ? 19.27417  8.05668   3.47594   1.000 57.30345  ? 169 GLN A CG   1 
ATOM   2582 C  CD   . GLN A 1 189 ? 20.12823  8.36858   2.25201   1.000 69.16568  ? 169 GLN A CD   1 
ATOM   2583 O  OE1  . GLN A 1 189 ? 19.69956  9.09376   1.34690   1.000 68.33130  ? 169 GLN A OE1  1 
ATOM   2584 N  NE2  . GLN A 1 189 ? 21.34540  7.81578   2.21887   1.000 63.74887  ? 169 GLN A NE2  1 
ATOM   2585 H  H    . GLN A 1 189 ? 15.71771  6.67376   2.40206   1.000 66.26366  ? 169 GLN A H    1 
ATOM   2586 H  HA   . GLN A 1 189 ? 18.11689  6.83434   1.29772   1.000 68.73837  ? 169 GLN A HA   1 
ATOM   2587 N  N    . GLU A 1 190 ? 17.68898  4.58329   3.54630   1.000 61.86072  ? 170 GLU A N    1 
ATOM   2588 C  CA   . GLU A 1 190 ? 18.27004  3.36092   4.08850   1.000 57.76846  ? 170 GLU A CA   1 
ATOM   2589 C  C    . GLU A 1 190 ? 18.52256  2.33944   2.98352   1.000 56.15795  ? 170 GLU A C    1 
ATOM   2590 O  O    . GLU A 1 190 ? 19.58144  1.70174   2.94433   1.000 52.10341  ? 170 GLU A O    1 
ATOM   2591 C  CB   . GLU A 1 190 ? 17.35096  2.77603   5.16120   1.000 54.90950  ? 170 GLU A CB   1 
ATOM   2592 H  H    . GLU A 1 190 ? 16.90318  4.76875   3.84247   1.000 74.25663  ? 170 GLU A H    1 
ATOM   2593 H  HA   . GLU A 1 190 ? 19.12003  3.57271   4.50511   1.000 69.34592  ? 170 GLU A HA   1 
ATOM   2594 N  N    . ASP A 1 191 ? 17.56286  2.17409   2.07079   1.000 45.58187  ? 171 ASP A N    1 
ATOM   2595 C  CA   . ASP A 1 191 ? 17.72518  1.18716   1.00812   1.000 46.55150  ? 171 ASP A CA   1 
ATOM   2596 C  C    . ASP A 1 191 ? 18.72812  1.65395   -0.04680  1.000 44.39658  ? 171 ASP A C    1 
ATOM   2597 O  O    . ASP A 1 191 ? 19.36374  0.82868   -0.71064  1.000 40.52380  ? 171 ASP A O    1 
ATOM   2598 C  CB   . ASP A 1 191 ? 16.36815  0.88551   0.37481   1.000 48.63111  ? 171 ASP A CB   1 
ATOM   2599 C  CG   . ASP A 1 191 ? 15.48573  0.00101   1.26038   1.000 59.32899  ? 171 ASP A CG   1 
ATOM   2600 O  OD1  . ASP A 1 191 ? 16.02678  -0.71136  2.13258   1.000 62.31005  ? 171 ASP A OD1  1 
ATOM   2601 O  OD2  . ASP A 1 191 ? 14.24757  0.01688   1.09022   1.000 61.87659  ? 171 ASP A OD2  1 
ATOM   2602 H  H    . ASP A 1 191 ? 16.82347  2.61259   2.04619   1.000 54.72201  ? 171 ASP A H    1 
ATOM   2603 H  HA   . ASP A 1 191 ? 18.06637  0.36239   1.38791   1.000 55.88557  ? 171 ASP A HA   1 
ATOM   2604 H  HB2  . ASP A 1 191 ? 15.89829  1.72011   0.22124   1.000 58.38110  ? 171 ASP A HB2  1 
ATOM   2605 H  HB3  . ASP A 1 191 ? 16.50753  0.42357   -0.46667  1.000 58.38110  ? 171 ASP A HB3  1 
ATOM   2606 N  N    . PHE A 1 192 ? 18.90508  2.96193   -0.20665  1.000 41.47824  ? 172 PHE A N    1 
ATOM   2607 C  CA   . PHE A 1 192 ? 19.99660  3.43878   -1.04678  1.000 39.19780  ? 172 PHE A CA   1 
ATOM   2608 C  C    . PHE A 1 192 ? 21.35348  3.05966   -0.44652  1.000 38.93150  ? 172 PHE A C    1 
ATOM   2609 O  O    . PHE A 1 192 ? 22.25176  2.59039   -1.15748  1.000 35.65504  ? 172 PHE A O    1 
ATOM   2610 C  CB   . PHE A 1 192 ? 19.89196  4.95193   -1.23263  1.000 40.38746  ? 172 PHE A CB   1 
ATOM   2611 C  CG   . PHE A 1 192 ? 21.00750  5.52591   -2.03647  1.000 46.24562  ? 172 PHE A CG   1 
ATOM   2612 C  CD1  . PHE A 1 192 ? 20.96509  5.48156   -3.42012  1.000 52.77827  ? 172 PHE A CD1  1 
ATOM   2613 C  CD2  . PHE A 1 192 ? 22.09515  6.10825   -1.42207  1.000 51.56586  ? 172 PHE A CD2  1 
ATOM   2614 C  CE1  . PHE A 1 192 ? 22.00033  6.00461   -4.17200  1.000 53.83565  ? 172 PHE A CE1  1 
ATOM   2615 C  CE2  . PHE A 1 192 ? 23.13017  6.63251   -2.16898  1.000 54.58920  ? 172 PHE A CE2  1 
ATOM   2616 C  CZ   . PHE A 1 192 ? 23.08114  6.57737   -3.54936  1.000 51.79066  ? 172 PHE A CZ   1 
ATOM   2617 H  H    . PHE A 1 192 ? 18.42112  3.57691   0.14998   1.000 49.79765  ? 172 PHE A H    1 
ATOM   2618 H  HA   . PHE A 1 192 ? 19.92663  3.02645   -1.92199  1.000 47.06113  ? 172 PHE A HA   1 
ATOM   2619 H  HB2  . PHE A 1 192 ? 19.06056  5.15506   -1.68915  1.000 48.48871  ? 172 PHE A HB2  1 
ATOM   2620 H  HB3  . PHE A 1 192 ? 19.90393  5.37655   -0.36059  1.000 48.48871  ? 172 PHE A HB3  1 
ATOM   2621 H  HD1  . PHE A 1 192 ? 20.23395  5.09663   -3.84691  1.000 63.35769  ? 172 PHE A HD1  1 
ATOM   2622 H  HD2  . PHE A 1 192 ? 22.13188  6.14829   -0.49366  1.000 61.90280  ? 172 PHE A HD2  1 
ATOM   2623 H  HE1  . PHE A 1 192 ? 21.96449  5.96841   -5.10061  1.000 64.62654  ? 172 PHE A HE1  1 
ATOM   2624 H  HE2  . PHE A 1 192 ? 23.85984  7.02248   -1.74424  1.000 65.53081  ? 172 PHE A HE2  1 
ATOM   2625 H  HZ   . PHE A 1 192 ? 23.77879  6.92750   -4.05492  1.000 62.17255  ? 172 PHE A HZ   1 
ATOM   2626 N  N    . GLN A 1 193 ? 21.50660  3.25173   0.85642   1.000 38.25142  ? 173 GLN A N    1 
ATOM   2627 C  CA   . GLN A 1 193 ? 22.74838  2.86846   1.52690   1.000 33.37030  ? 173 GLN A CA   1 
ATOM   2628 C  C    . GLN A 1 193 ? 23.02023  1.37590   1.36643   1.000 35.25988  ? 173 GLN A C    1 
ATOM   2629 O  O    . GLN A 1 193 ? 24.15215  0.96988   1.09112   1.000 35.30271  ? 173 GLN A O    1 
ATOM   2630 C  CB   . GLN A 1 193 ? 22.69990  3.23543   3.00969   1.000 36.07091  ? 173 GLN A CB   1 
ATOM   2631 C  CG   . GLN A 1 193 ? 24.07181  3.08745   3.69569   1.000 37.16930  ? 173 GLN A CG   1 
ATOM   2632 C  CD   . GLN A 1 193 ? 25.12400  3.97514   3.06445   1.000 43.38023  ? 173 GLN A CD   1 
ATOM   2633 O  OE1  . GLN A 1 193 ? 25.06502  5.20493   3.17861   1.000 46.96405  ? 173 GLN A OE1  1 
ATOM   2634 N  NE2  . GLN A 1 193 ? 26.08907  3.36496   2.38788   1.000 46.35459  ? 173 GLN A NE2  1 
ATOM   2635 H  H    . GLN A 1 193 ? 20.91463  3.59881   1.37480   1.000 45.92547  ? 173 GLN A H    1 
ATOM   2636 H  HA   . GLN A 1 193 ? 23.47727  3.36382   1.12165   1.000 40.06812  ? 173 GLN A HA   1 
ATOM   2637 H  HB2  . GLN A 1 193 ? 22.41568  4.15856   3.09881   1.000 43.30885  ? 173 GLN A HB2  1 
ATOM   2638 H  HB3  . GLN A 1 193 ? 22.07187  2.64990   3.46094   1.000 43.30885  ? 173 GLN A HB3  1 
ATOM   2639 H  HG2  . GLN A 1 193 ? 23.98890  3.33400   4.63017   1.000 44.62692  ? 173 GLN A HG2  1 
ATOM   2640 H  HG3  . GLN A 1 193 ? 24.36787  2.16681   3.62049   1.000 44.62692  ? 173 GLN A HG3  1 
ATOM   2641 H  HE21 . GLN A 1 193 ? 26.09443  2.50724   2.32558   1.000 55.64927  ? 173 GLN A HE21 1 
ATOM   2642 H  HE22 . GLN A 1 193 ? 26.70906  3.82730   2.01177   1.000 55.64927  ? 173 GLN A HE22 1 
ATOM   2643 N  N    . ILE A 1 194 ? 21.98498  0.55124   1.48548   1.000 34.65746  ? 174 ILE A N    1 
ATOM   2644 C  CA   . ILE A 1 194 ? 22.15583  -0.89158  1.30183   1.000 36.97825  ? 174 ILE A CA   1 
ATOM   2645 C  C    . ILE A 1 194 ? 22.60491  -1.21771  -0.11701  1.000 36.56494  ? 174 ILE A C    1 
ATOM   2646 O  O    . ILE A 1 194 ? 23.45218  -2.10278  -0.32484  1.000 33.51157  ? 174 ILE A O    1 
ATOM   2647 C  CB   . ILE A 1 194 ? 20.85435  -1.61477  1.69074   1.000 36.90101  ? 174 ILE A CB   1 
ATOM   2648 C  CG1  . ILE A 1 194 ? 20.62016  -1.44881  3.19516   1.000 45.33540  ? 174 ILE A CG1  1 
ATOM   2649 C  CG2  . ILE A 1 194 ? 20.91834  -3.08571  1.28608   1.000 44.99471  ? 174 ILE A CG2  1 
ATOM   2650 C  CD1  . ILE A 1 194 ? 19.36234  -2.12579  3.71248   1.000 48.70361  ? 174 ILE A CD1  1 
ATOM   2651 H  H    . ILE A 1 194 ? 21.18108  0.79494   1.66976   1.000 41.61271  ? 174 ILE A H    1 
ATOM   2652 H  HA   . ILE A 1 194 ? 22.86195  -1.20213  1.88992   1.000 44.39766  ? 174 ILE A HA   1 
ATOM   2653 H  HB   . ILE A 1 194 ? 20.10640  -1.21939  1.21625   1.000 44.30497  ? 174 ILE A HB   1 
ATOM   2654 H  HG12 . ILE A 1 194 ? 21.37513  -1.83042  3.66982   1.000 54.42624  ? 174 ILE A HG12 1 
ATOM   2655 H  HG13 . ILE A 1 194 ? 20.54705  -0.50232  3.39442   1.000 54.42624  ? 174 ILE A HG13 1 
ATOM   2656 H  HG21 . ILE A 1 194 ? 20.12969  -3.54009  1.62143   1.000 54.01742  ? 174 ILE A HG21 1 
ATOM   2657 H  HG22 . ILE A 1 194 ? 20.94846  -3.14602  0.31843   1.000 54.01742  ? 174 ILE A HG22 1 
ATOM   2658 H  HG23 . ILE A 1 194 ? 21.71658  -3.48368  1.66732   1.000 54.01742  ? 174 ILE A HG23 1 
ATOM   2659 H  HD11 . ILE A 1 194 ? 19.12849  -1.74283  4.57245   1.000 58.46810  ? 174 ILE A HD11 1 
ATOM   2660 H  HD12 . ILE A 1 194 ? 18.64227  -1.98071  3.07896   1.000 58.46810  ? 174 ILE A HD12 1 
ATOM   2661 H  HD13 . ILE A 1 194 ? 19.53188  -3.07601  3.80864   1.000 58.46810  ? 174 ILE A HD13 1 
ATOM   2662 N  N    . THR A 1 195 ? 22.05913  -0.50748  -1.11164  1.000 31.35503  ? 175 THR A N    1 
ATOM   2663 C  CA   . THR A 1 195 ? 22.46749  -0.73086  -2.48898  1.000 30.64071  ? 175 THR A CA   1 
ATOM   2664 C  C    . THR A 1 195 ? 23.93862  -0.38225  -2.67034  1.000 30.36544  ? 175 THR A C    1 
ATOM   2665 O  O    . THR A 1 195 ? 24.67476  -1.10055  -3.36073  1.000 28.82353  ? 175 THR A O    1 
ATOM   2666 C  CB   . THR A 1 195 ? 21.58173  0.09304   -3.43049  1.000 36.43647  ? 175 THR A CB   1 
ATOM   2667 O  OG1  . THR A 1 195 ? 20.21702  -0.23999  -3.17372  1.000 40.08167  ? 175 THR A OG1  1 
ATOM   2668 C  CG2  . THR A 1 195 ? 21.88893  -0.22200  -4.86119  1.000 34.20592  ? 175 THR A CG2  1 
ATOM   2669 H  H    . THR A 1 195 ? 21.45893  0.10013   -1.01080  1.000 37.64980  ? 175 THR A H    1 
ATOM   2670 H  HA   . THR A 1 195 ? 22.34998  -1.66569  -2.71960  1.000 36.79261  ? 175 THR A HA   1 
ATOM   2671 H  HB   . THR A 1 195 ? 21.73899  1.03916   -3.28553  1.000 43.74752  ? 175 THR A HB   1 
ATOM   2672 H  HG1  . THR A 1 195 ? 20.01971  -0.05092  -2.37941  1.000 48.12176  ? 175 THR A HG1  1 
ATOM   2673 H  HG21 . THR A 1 195 ? 21.50123  0.45284   -5.44013  1.000 41.07086  ? 175 THR A HG21 1 
ATOM   2674 H  HG22 . THR A 1 195 ? 22.84905  -0.24033  -4.99809  1.000 41.07086  ? 175 THR A HG22 1 
ATOM   2675 H  HG23 . THR A 1 195 ? 21.52079  -1.08798  -5.09664  1.000 41.07086  ? 175 THR A HG23 1 
ATOM   2676 N  N    . MET A 1 196 ? 24.36551  0.74800   -2.11067  1.000 29.88769  ? 176 MET A N    1 
ATOM   2677 C  CA   . MET A 1 196 ? 25.74789  1.15949   -2.27227  1.000 30.19586  ? 176 MET A CA   1 
ATOM   2678 C  C    . MET A 1 196 ? 26.67715  0.16275   -1.58632  1.000 29.86844  ? 176 MET A C    1 
ATOM   2679 O  O    . MET A 1 196 ? 27.77691  -0.11755  -2.08056  1.000 31.01583  ? 176 MET A O    1 
ATOM   2680 C  CB   . MET A 1 196 ? 25.96055  2.56324   -1.70854  1.000 36.71549  ? 176 MET A CB   1 
ATOM   2681 C  CG   . MET A 1 196 ? 25.39399  3.69912   -2.59705  1.000 45.30141  ? 176 MET A CG   1 
ATOM   2682 S  SD   . MET A 1 196 ? 25.40245  3.40314   -4.38627  1.000 71.09068  ? 176 MET A SD   1 
ATOM   2683 C  CE   . MET A 1 196 ? 27.14793  3.65737   -4.74934  1.000 62.50567  ? 176 MET A CE   1 
ATOM   2684 H  H    . MET A 1 196 ? 23.88104  1.28201   -1.64192  1.000 35.88899  ? 176 MET A H    1 
ATOM   2685 H  HA   . MET A 1 196 ? 25.95371  1.19893   -3.21936  1.000 36.25879  ? 176 MET A HA   1 
ATOM   2686 H  HB2  . MET A 1 196 ? 25.52292  2.61973   -0.84471  1.000 44.08235  ? 176 MET A HB2  1 
ATOM   2687 H  HB3  . MET A 1 196 ? 26.91323  2.71581   -1.60841  1.000 44.08235  ? 176 MET A HB3  1 
ATOM   2688 H  HG2  . MET A 1 196 ? 24.47182  3.85322   -2.33865  1.000 54.38545  ? 176 MET A HG2  1 
ATOM   2689 H  HG3  . MET A 1 196 ? 25.92089  4.49794   -2.43845  1.000 54.38545  ? 176 MET A HG3  1 
ATOM   2690 H  HE1  . MET A 1 196 ? 27.29757  3.51374   -5.69691  1.000 75.03056  ? 176 MET A HE1  1 
ATOM   2691 H  HE2  . MET A 1 196 ? 27.39132  4.56529   -4.50991  1.000 75.03056  ? 176 MET A HE2  1 
ATOM   2692 H  HE3  . MET A 1 196 ? 27.67316  3.02680   -4.23221  1.000 75.03056  ? 176 MET A HE3  1 
ATOM   2693 N  N    . ASP A 1 197 ? 26.26736  -0.34160  -0.41836  1.000 30.39393  ? 177 ASP A N    1 
ATOM   2694 C  CA   . ASP A 1 197 ? 27.11733  -1.30371  0.29616   1.000 29.00413  ? 177 ASP A CA   1 
ATOM   2695 C  C    . ASP A 1 197 ? 27.26441  -2.59887  -0.50917  1.000 27.48401  ? 177 ASP A C    1 
ATOM   2696 O  O    . ASP A 1 197 ? 28.35849  -3.19564  -0.51844  1.000 29.90730  ? 177 ASP A O    1 
ATOM   2697 C  CB   . ASP A 1 197 ? 26.52871  -1.60391  1.66559   1.000 31.81339  ? 177 ASP A CB   1 
ATOM   2698 C  CG   . ASP A 1 197 ? 26.46514  -0.39105  2.57138   1.000 34.83141  ? 177 ASP A CG   1 
ATOM   2699 O  OD1  . ASP A 1 197 ? 27.16708  0.65502   2.36864   1.000 36.97591  ? 177 ASP A OD1  1 
ATOM   2700 O  OD2  . ASP A 1 197 ? 25.73234  -0.50149  3.58198   1.000 41.13069  ? 177 ASP A OD2  1 
ATOM   2701 H  H    . ASP A 1 197 ? 25.52514  -0.15064  -0.02818  1.000 36.49647  ? 177 ASP A H    1 
ATOM   2702 H  HA   . ASP A 1 197 ? 27.99647  -0.91416  0.42364   1.000 34.82872  ? 177 ASP A HA   1 
ATOM   2703 H  HB2  . ASP A 1 197 ? 25.62517  -1.93812  1.55233   1.000 38.19983  ? 177 ASP A HB2  1 
ATOM   2704 H  HB3  . ASP A 1 197 ? 27.07763  -2.27334  2.10315   1.000 38.19983  ? 177 ASP A HB3  1 
ATOM   2705 N  N    . ALA A 1 198 ? 26.16322  -3.07106  -1.09317  1.000 27.72260  ? 178 ALA A N    1 
ATOM   2706 C  CA   . ALA A 1 198 ? 26.15709  -4.25179  -1.97067  1.000 26.63093  ? 178 ALA A CA   1 
ATOM   2707 C  C    . ALA A 1 198 ? 27.08101  -4.04147  -3.15721  1.000 30.74249  ? 178 ALA A C    1 
ATOM   2708 O  O    . ALA A 1 198 ? 27.92246  -4.89849  -3.47172  1.000 26.97585  ? 178 ALA A O    1 
ATOM   2709 C  CB   . ALA A 1 198 ? 24.74545  -4.57862  -2.43354  1.000 29.77048  ? 178 ALA A CB   1 
ATOM   2710 H  H    . ALA A 1 198 ? 25.38357  -2.72066  -0.99851  1.000 33.29089  ? 178 ALA A H    1 
ATOM   2711 H  HA   . ALA A 1 198 ? 26.47471  -5.01493  -1.46309  1.000 31.98088  ? 178 ALA A HA   1 
ATOM   2712 H  HB1  . ALA A 1 198 ? 24.76548  -5.39620  -2.95513  1.000 35.74834  ? 178 ALA A HB1  1 
ATOM   2713 H  HB2  . ALA A 1 198 ? 24.17743  -4.69609  -1.65607  1.000 35.74834  ? 178 ALA A HB2  1 
ATOM   2714 H  HB3  . ALA A 1 198 ? 24.41423  -3.84713  -2.97770  1.000 35.74834  ? 178 ALA A HB3  1 
ATOM   2715 N  N    . PHE A 1 199 ? 26.98796  -2.87391  -3.79783  1.000 26.57372  ? 179 PHE A N    1 
ATOM   2716 C  CA   . PHE A 1 199 ? 27.90131  -2.60783  -4.90482  1.000 28.37510  ? 179 PHE A CA   1 
ATOM   2717 C  C    . PHE A 1 199 ? 29.36163  -2.63936  -4.44014  1.000 25.67050  ? 179 PHE A C    1 
ATOM   2718 O  O    . PHE A 1 199 ? 30.22725  -3.20616  -5.12549  1.000 28.32404  ? 179 PHE A O    1 
ATOM   2719 C  CB   . PHE A 1 199 ? 27.56664  -1.26408  -5.58577  1.000 26.76605  ? 179 PHE A CB   1 
ATOM   2720 C  CG   . PHE A 1 199 ? 28.51890  -0.95291  -6.70368  1.000 29.49298  ? 179 PHE A CG   1 
ATOM   2721 C  CD1  . PHE A 1 199 ? 28.33478  -1.52876  -7.94559  1.000 30.98489  ? 179 PHE A CD1  1 
ATOM   2722 C  CD2  . PHE A 1 199 ? 29.64173  -0.18061  -6.48555  1.000 31.91585  ? 179 PHE A CD2  1 
ATOM   2723 C  CE1  . PHE A 1 199 ? 29.25706  -1.29566  -8.95664  1.000 31.86130  ? 179 PHE A CE1  1 
ATOM   2724 C  CE2  . PHE A 1 199 ? 30.55477  0.04454   -7.48778  1.000 33.73381  ? 179 PHE A CE2  1 
ATOM   2725 C  CZ   . PHE A 1 199 ? 30.34504  -0.50249  -8.73590  1.000 32.73207  ? 179 PHE A CZ   1 
ATOM   2726 H  H    . PHE A 1 199 ? 26.42801  -2.24653  -3.61767  1.000 31.91223  ? 179 PHE A H    1 
ATOM   2727 H  HA   . PHE A 1 199 ? 27.78312  -3.30262  -5.57131  1.000 34.07388  ? 179 PHE A HA   1 
ATOM   2728 H  HB2  . PHE A 1 199 ? 26.66984  -1.30673  -5.95297  1.000 32.14302  ? 179 PHE A HB2  1 
ATOM   2729 H  HB3  . PHE A 1 199 ? 27.62326  -0.55113  -4.93049  1.000 32.14302  ? 179 PHE A HB3  1 
ATOM   2730 H  HD1  . PHE A 1 199 ? 27.59571  -2.07063  -8.10386  1.000 37.20563  ? 179 PHE A HD1  1 
ATOM   2731 H  HD2  . PHE A 1 199 ? 29.78291  0.19383   -5.64604  1.000 38.32278  ? 179 PHE A HD2  1 
ATOM   2732 H  HE1  . PHE A 1 199 ? 29.13212  -1.68388  -9.79245  1.000 38.25733  ? 179 PHE A HE1  1 
ATOM   2733 H  HE2  . PHE A 1 199 ? 31.30963  0.56281   -7.32506  1.000 40.50433  ? 179 PHE A HE2  1 
ATOM   2734 H  HZ   . PHE A 1 199 ? 30.94421  -0.33109  -9.42620  1.000 39.30224  ? 179 PHE A HZ   1 
ATOM   2735 N  N    . ALA A 1 200 ? 29.67140  -2.03774  -3.28399  1.000 24.94601  ? 180 ALA A N    1 
ATOM   2736 C  CA   . ALA A 1 200 ? 31.03479  -1.98869  -2.78819  1.000 26.04640  ? 180 ALA A CA   1 
ATOM   2737 C  C    . ALA A 1 200 ? 31.56901  -3.39695  -2.58298  1.000 28.16731  ? 180 ALA A C    1 
ATOM   2738 O  O    . ALA A 1 200 ? 32.74817  -3.65934  -2.81359  1.000 28.16946  ? 180 ALA A O    1 
ATOM   2739 C  CB   . ALA A 1 200 ? 31.11631  -1.20762  -1.47445  1.000 28.50565  ? 180 ALA A CB   1 
ATOM   2740 H  H    . ALA A 1 200 ? 29.10130  -1.65003  -2.76993  1.000 29.95897  ? 180 ALA A H    1 
ATOM   2741 H  HA   . ALA A 1 200 ? 31.58278  -1.52291  -3.43908  1.000 31.27944  ? 180 ALA A HA   1 
ATOM   2742 H  HB1  . ALA A 1 200 ? 32.03649  -1.20083  -1.16766  1.000 34.23054  ? 180 ALA A HB1  1 
ATOM   2743 H  HB2  . ALA A 1 200 ? 30.81198  -0.29942  -1.62761  1.000 34.23054  ? 180 ALA A HB2  1 
ATOM   2744 H  HB3  . ALA A 1 200 ? 30.55091  -1.63913  -0.81489  1.000 34.23054  ? 180 ALA A HB3  1 
ATOM   2745 N  N    . ALA A 1 201 ? 30.72335  -4.29208  -2.08771  1.000 27.09155  ? 181 ALA A N    1 
ATOM   2746 C  CA   . ALA A 1 201 ? 31.16693  -5.66543  -1.84465  1.000 30.26063  ? 181 ALA A CA   1 
ATOM   2747 C  C    . ALA A 1 201 ? 31.41868  -6.40224  -3.15907  1.000 26.22234  ? 181 ALA A C    1 
ATOM   2748 O  O    . ALA A 1 201 ? 32.43743  -7.10985  -3.27990  1.000 29.43917  ? 181 ALA A O    1 
ATOM   2749 C  CB   . ALA A 1 201 ? 30.12009  -6.39953  -0.99495  1.000 28.95056  ? 181 ALA A CB   1 
ATOM   2750 H  H    . ALA A 1 201 ? 29.90179  -4.13717  -1.88610  1.000 32.53362  ? 181 ALA A H    1 
ATOM   2751 H  HA   . ALA A 1 201 ? 32.00100  -5.65212  -1.34963  1.000 36.33651  ? 181 ALA A HA   1 
ATOM   2752 H  HB1  . ALA A 1 201 ? 30.44871  -7.28824  -0.78733  1.000 34.76443  ? 181 ALA A HB1  1 
ATOM   2753 H  HB2  . ALA A 1 201 ? 29.97276  -5.90157  -0.17567  1.000 34.76443  ? 181 ALA A HB2  1 
ATOM   2754 H  HB3  . ALA A 1 201 ? 29.29276  -6.46183  -1.49749  1.000 34.76443  ? 181 ALA A HB3  1 
ATOM   2755 N  N    . TYR A 1 202 ? 30.52712  -6.21503  -4.13618  1.000 26.94029  ? 182 TYR A N    1 
ATOM   2756 C  CA   . TYR A 1 202 ? 30.70068  -6.81421  -5.45577  1.000 23.92881  ? 182 TYR A CA   1 
ATOM   2757 C  C    . TYR A 1 202 ? 31.95675  -6.27390  -6.11364  1.000 26.06060  ? 182 TYR A C    1 
ATOM   2758 O  O    . TYR A 1 202 ? 32.73850  -7.03864  -6.70704  1.000 27.02351  ? 182 TYR A O    1 
ATOM   2759 C  CB   . TYR A 1 202 ? 29.46855  -6.55936  -6.33180  1.000 25.98014  ? 182 TYR A CB   1 
ATOM   2760 C  CG   . TYR A 1 202 ? 29.71000  -7.15366  -7.69893  1.000 25.03305  ? 182 TYR A CG   1 
ATOM   2761 C  CD1  . TYR A 1 202 ? 29.54095  -8.51410  -7.90687  1.000 27.07577  ? 182 TYR A CD1  1 
ATOM   2762 C  CD2  . TYR A 1 202 ? 30.17409  -6.37583  -8.74610  1.000 27.12881  ? 182 TYR A CD2  1 
ATOM   2763 C  CE1  . TYR A 1 202 ? 29.78139  -9.10225  -9.14228  1.000 28.90536  ? 182 TYR A CE1  1 
ATOM   2764 C  CE2  . TYR A 1 202 ? 30.41177  -6.95430  -10.01306 1.000 26.77887  ? 182 TYR A CE2  1 
ATOM   2765 C  CZ   . TYR A 1 202 ? 30.21893  -8.31260  -10.18780 1.000 26.75961  ? 182 TYR A CZ   1 
ATOM   2766 O  OH   . TYR A 1 202 ? 30.51740  -8.94004  -11.36477 1.000 31.07852  ? 182 TYR A OH   1 
ATOM   2767 H  H    . TYR A 1 202 ? 29.81184  -5.74385  -4.05888  1.000 32.35211  ? 182 TYR A H    1 
ATOM   2768 H  HA   . TYR A 1 202 ? 30.78723  -7.77582  -5.36241  1.000 28.73834  ? 182 TYR A HA   1 
ATOM   2769 H  HB2  . TYR A 1 202 ? 28.68919  -6.98052  -5.93667  1.000 31.19993  ? 182 TYR A HB2  1 
ATOM   2770 H  HB3  . TYR A 1 202 ? 29.31954  -5.60524  -6.42318  1.000 31.19993  ? 182 TYR A HB3  1 
ATOM   2771 H  HD1  . TYR A 1 202 ? 29.25868  -9.04780  -7.19948  1.000 32.51468  ? 182 TYR A HD1  1 
ATOM   2772 H  HD2  . TYR A 1 202 ? 30.33010  -5.46844  -8.61494  1.000 32.57834  ? 182 TYR A HD2  1 
ATOM   2773 H  HE1  . TYR A 1 202 ? 29.64962  -10.01483 -9.26370  1.000 34.71019  ? 182 TYR A HE1  1 
ATOM   2774 H  HE2  . TYR A 1 202 ? 30.69562  -6.42591  -10.72379 1.000 32.15841  ? 182 TYR A HE2  1 
ATOM   2775 H  HH   . TYR A 1 202 ? 30.81123  -8.38314  -11.92076 1.000 37.31799  ? 182 TYR A HH   1 
ATOM   2776 N  N    . ASN A 1 203 ? 32.15565  -4.94400  -6.04370  1.000 23.95572  ? 183 ASN A N    1 
ATOM   2777 C  CA   . ASN A 1 203 ? 33.36374  -4.31766  -6.58368  1.000 28.47967  ? 183 ASN A CA   1 
ATOM   2778 C  C    . ASN A 1 203 ? 34.62414  -4.94553  -6.00951  1.000 29.24355  ? 183 ASN A C    1 
ATOM   2779 O  O    . ASN A 1 203 ? 35.60135  -5.20586  -6.72980  1.000 31.99596  ? 183 ASN A O    1 
ATOM   2780 C  CB   . ASN A 1 203 ? 33.31377  -2.80396  -6.30730  1.000 28.82010  ? 183 ASN A CB   1 
ATOM   2781 C  CG   . ASN A 1 203 ? 34.51982  -2.09016  -6.80963  1.000 31.49789  ? 183 ASN A CG   1 
ATOM   2782 O  OD1  . ASN A 1 203 ? 34.70020  -1.96552  -8.01549  1.000 35.77171  ? 183 ASN A OD1  1 
ATOM   2783 N  ND2  . ASN A 1 203 ? 35.34366  -1.57781  -5.90225  1.000 31.60027  ? 183 ASN A ND2  1 
ATOM   2784 H  H    . ASN A 1 203 ? 31.60436  -4.38782  -5.68825  1.000 28.77063  ? 183 ASN A H    1 
ATOM   2785 H  HA   . ASN A 1 203 ? 33.39359  -4.45256  -7.54379  1.000 34.19937  ? 183 ASN A HA   1 
ATOM   2786 H  HB2  . ASN A 1 203 ? 32.53618  -2.42712  -6.74804  1.000 34.60789  ? 183 ASN A HB2  1 
ATOM   2787 H  HB3  . ASN A 1 203 ? 33.25548  -2.65862  -5.35003  1.000 34.60789  ? 183 ASN A HB3  1 
ATOM   2788 H  HD21 . ASN A 1 203 ? 36.05139  -1.15806  -6.15232  1.000 37.94408  ? 183 ASN A HD21 1 
ATOM   2789 H  HD22 . ASN A 1 203 ? 35.16930  -1.66586  -5.06472  1.000 37.94408  ? 183 ASN A HD22 1 
ATOM   2790 N  N    . ASP A 1 204 ? 34.67891  -5.08594  -4.67844  1.000 28.04848  ? 184 ASP A N    1 
ATOM   2791 C  CA   . ASP A 1 204 ? 35.84903  -5.64142  -4.02882  1.000 30.78470  ? 184 ASP A CA   1 
ATOM   2792 C  C    . ASP A 1 204 ? 36.13294  -7.04960  -4.53505  1.000 29.64903  ? 184 ASP A C    1 
ATOM   2793 O  O    . ASP A 1 204 ? 37.27822  -7.37048  -4.89092  1.000 33.30180  ? 184 ASP A O    1 
ATOM   2794 C  CB   . ASP A 1 204 ? 35.62292  -5.64087  -2.51338  1.000 29.51022  ? 184 ASP A CB   1 
ATOM   2795 C  CG   . ASP A 1 204 ? 36.81434  -6.10920  -1.75334  1.000 32.29295  ? 184 ASP A CG   1 
ATOM   2796 O  OD1  . ASP A 1 204 ? 37.86532  -5.41015  -1.70637  1.000 36.21867  ? 184 ASP A OD1  1 
ATOM   2797 O  OD2  . ASP A 1 204 ? 36.73814  -7.22463  -1.18918  1.000 38.78920  ? 184 ASP A OD2  1 
ATOM   2798 H  H    . ASP A 1 204 ? 34.04795  -4.86481  -4.13752  1.000 33.68194  ? 184 ASP A H    1 
ATOM   2799 H  HA   . ASP A 1 204 ? 36.62520  -5.09433  -4.22669  1.000 36.96540  ? 184 ASP A HA   1 
ATOM   2800 H  HB2  . ASP A 1 204 ? 35.41887  -4.73763  -2.22453  1.000 35.43602  ? 184 ASP A HB2  1 
ATOM   2801 H  HB3  . ASP A 1 204 ? 34.88241  -6.23139  -2.30402  1.000 35.43602  ? 184 ASP A HB3  1 
ATOM   2802 N  N    . PHE A 1 205 ? 35.10937  -7.90642  -4.53229  1.000 29.43602  ? 185 PHE A N    1 
ATOM   2803 C  CA   . PHE A 1 205 ? 35.27988  -9.28896  -4.96882  1.000 29.28990  ? 185 PHE A CA   1 
ATOM   2804 C  C    . PHE A 1 205 ? 35.78070  -9.34042  -6.39785  1.000 30.91736  ? 185 PHE A C    1 
ATOM   2805 O  O    . PHE A 1 205 ? 36.75189  -10.05206 -6.70054  1.000 32.58735  ? 185 PHE A O    1 
ATOM   2806 C  CB   . PHE A 1 205 ? 33.95640  -10.04345 -4.83273  1.000 32.66699  ? 185 PHE A CB   1 
ATOM   2807 C  CG   . PHE A 1 205 ? 34.01552  -11.46032 -5.32455  1.000 34.12860  ? 185 PHE A CG   1 
ATOM   2808 C  CD1  . PHE A 1 205 ? 33.76039  -11.74710 -6.66054  1.000 37.48965  ? 185 PHE A CD1  1 
ATOM   2809 C  CD2  . PHE A 1 205 ? 34.31443  -12.49256 -4.46912  1.000 38.84170  ? 185 PHE A CD2  1 
ATOM   2810 C  CE1  . PHE A 1 205 ? 33.83623  -13.05447 -7.11468  1.000 37.97709  ? 185 PHE A CE1  1 
ATOM   2811 C  CE2  . PHE A 1 205 ? 34.36788  -13.79792 -4.93267  1.000 39.23843  ? 185 PHE A CE2  1 
ATOM   2812 C  CZ   . PHE A 1 205 ? 34.16201  -14.06026 -6.24365  1.000 35.93006  ? 185 PHE A CZ   1 
ATOM   2813 H  H    . PHE A 1 205 ? 34.30962  -7.71175  -4.28308  1.000 35.34699  ? 185 PHE A H    1 
ATOM   2814 H  HA   . PHE A 1 205 ? 35.93426  -9.72467  -4.40062  1.000 35.17165  ? 185 PHE A HA   1 
ATOM   2815 H  HB2  . PHE A 1 205 ? 33.70459  -10.06528 -3.89624  1.000 39.22414  ? 185 PHE A HB2  1 
ATOM   2816 H  HB3  . PHE A 1 205 ? 33.27820  -9.57917  -5.34790  1.000 39.22414  ? 185 PHE A HB3  1 
ATOM   2817 H  HD1  . PHE A 1 205 ? 33.53893  -11.06215 -7.24935  1.000 45.01135  ? 185 PHE A HD1  1 
ATOM   2818 H  HD2  . PHE A 1 205 ? 34.48227  -12.31434 -3.57192  1.000 46.63381  ? 185 PHE A HD2  1 
ATOM   2819 H  HE1  . PHE A 1 205 ? 33.66641  -13.24828 -8.00827  1.000 45.59626  ? 185 PHE A HE1  1 
ATOM   2820 H  HE2  . PHE A 1 205 ? 34.54542  -14.49387 -4.34187  1.000 47.10988  ? 185 PHE A HE2  1 
ATOM   2821 H  HZ   . PHE A 1 205 ? 34.24246  -14.93227 -6.55675  1.000 43.13983  ? 185 PHE A HZ   1 
ATOM   2822 N  N    . THR A 1 206 ? 35.15696  -8.55967  -7.27065  1.000 30.33277  ? 186 THR A N    1 
ATOM   2823 C  CA   . THR A 1 206 ? 35.45867  -8.65535  -8.69599  1.000 31.54765  ? 186 THR A CA   1 
ATOM   2824 C  C    . THR A 1 206 ? 36.84915  -8.13285  -8.99606  1.000 29.85068  ? 186 THR A C    1 
ATOM   2825 O  O    . THR A 1 206 ? 37.57586  -8.70905  -9.81762  1.000 35.25601  ? 186 THR A O    1 
ATOM   2826 C  CB   . THR A 1 206 ? 34.39775  -7.91745  -9.50540  1.000 28.80229  ? 186 THR A CB   1 
ATOM   2827 O  OG1  . THR A 1 206 ? 33.10148  -8.40543  -9.15946  1.000 28.53554  ? 186 THR A OG1  1 
ATOM   2828 C  CG2  . THR A 1 206 ? 34.62827  -8.14528  -10.98918 1.000 29.92356  ? 186 THR A CG2  1 
ATOM   2829 H  H    . THR A 1 206 ? 34.56177  -7.97256  -7.06903  1.000 36.42308  ? 186 THR A H    1 
ATOM   2830 H  HA   . THR A 1 206 ? 35.43270  -9.58661  -8.96611  1.000 37.88095  ? 186 THR A HA   1 
ATOM   2831 H  HB   . THR A 1 206 ? 34.44650  -6.96716  -9.31710  1.000 34.58651  ? 186 THR A HB   1 
ATOM   2832 H  HG1  . THR A 1 206 ? 33.07300  -9.23929  -9.25680  1.000 34.26641  ? 186 THR A HG1  1 
ATOM   2833 H  HG21 . THR A 1 206 ? 33.90659  -7.74864  -11.50178 1.000 35.93203  ? 186 THR A HG21 1 
ATOM   2834 H  HG22 . THR A 1 206 ? 35.46682  -7.74027  -11.26067 1.000 35.93203  ? 186 THR A HG22 1 
ATOM   2835 H  HG23 . THR A 1 206 ? 34.66247  -9.09622  -11.17744 1.000 35.93203  ? 186 THR A HG23 1 
ATOM   2836 N  N    . ARG A 1 207 ? 37.29237  -7.08362  -8.30177  1.000 30.71938  ? 187 ARG A N    1 
ATOM   2837 C  CA   . ARG A 1 207 ? 38.64253  -6.58435  -8.57984  1.000 32.85038  ? 187 ARG A CA   1 
ATOM   2838 C  C    . ARG A 1 207 ? 39.70949  -7.54431  -8.08939  1.000 34.28165  ? 187 ARG A C    1 
ATOM   2839 O  O    . ARG A 1 207 ? 40.80172  -7.62640  -8.67826  1.000 38.68322  ? 187 ARG A O    1 
ATOM   2840 C  CB   . ARG A 1 207 ? 38.82873  -5.20002  -7.96607  1.000 37.82243  ? 187 ARG A CB   1 
ATOM   2841 C  CG   . ARG A 1 207 ? 38.16483  -4.10303  -8.80282  1.000 35.40624  ? 187 ARG A CG   1 
ATOM   2842 C  CD   . ARG A 1 207 ? 38.15214  -2.77468  -8.08948  1.000 40.32093  ? 187 ARG A CD   1 
ATOM   2843 N  NE   . ARG A 1 207 ? 37.39771  -1.74623  -8.80301  1.000 38.21154  ? 187 ARG A NE   1 
ATOM   2844 C  CZ   . ARG A 1 207 ? 37.85193  -1.02346  -9.82342  1.000 38.40299  ? 187 ARG A CZ   1 
ATOM   2845 N  NH1  . ARG A 1 207 ? 39.07479  -1.18637  -10.30313 1.000 41.74604  ? 187 ARG A NH1  1 
ATOM   2846 N  NH2  . ARG A 1 207 ? 37.06336  -0.09729  -10.36013 1.000 39.70113  ? 187 ARG A NH2  1 
ATOM   2847 H  H    . ARG A 1 207 ? 36.85431  -6.66189  -7.69361  1.000 36.88702  ? 187 ARG A H    1 
ATOM   2848 H  HA   . ARG A 1 207 ? 38.75125  -6.49462  -9.53954  1.000 39.44422  ? 187 ARG A HA   1 
ATOM   2849 H  HB2  . ARG A 1 207 ? 38.43126  -5.18844  -7.08131  1.000 45.41068  ? 187 ARG A HB2  1 
ATOM   2850 H  HB3  . ARG A 1 207 ? 39.77675  -5.00356  -7.90647  1.000 45.41068  ? 187 ARG A HB3  1 
ATOM   2851 H  HG2  . ARG A 1 207 ? 38.65397  -3.99540  -9.63352  1.000 42.51125  ? 187 ARG A HG2  1 
ATOM   2852 H  HG3  . ARG A 1 207 ? 37.24679  -4.35514  -8.98866  1.000 42.51125  ? 187 ARG A HG3  1 
ATOM   2853 H  HD2  . ARG A 1 207 ? 37.74602  -2.89026  -7.21621  1.000 48.40887  ? 187 ARG A HD2  1 
ATOM   2854 H  HD3  . ARG A 1 207 ? 39.06485  -2.46105  -7.99201  1.000 48.40887  ? 187 ARG A HD3  1 
ATOM   2855 H  HE   . ARG A 1 207 ? 36.59247  -1.59562  -8.54126  1.000 45.87761  ? 187 ARG A HE   1 
ATOM   2856 H  HH11 . ARG A 1 207 ? 39.59909  -1.77201  -9.95422  1.000 50.11900  ? 187 ARG A HH11 1 
ATOM   2857 H  HH12 . ARG A 1 207 ? 39.34501  -0.70659  -10.96373 1.000 50.11900  ? 187 ARG A HH12 1 
ATOM   2858 H  HH21 . ARG A 1 207 ? 36.27208  0.02757   -10.04727 1.000 47.66512  ? 187 ARG A HH21 1 
ATOM   2859 H  HH22 . ARG A 1 207 ? 37.34456  0.37692   -11.02017 1.000 47.66512  ? 187 ARG A HH22 1 
ATOM   2860 N  N    . ALA A 1 208 ? 39.42322  -8.28175  -7.01635  1.000 36.64555  ? 188 ALA A N    1 
ATOM   2861 C  CA   . ALA A 1 208 ? 40.30742  -9.36446  -6.61516  1.000 38.51204  ? 188 ALA A CA   1 
ATOM   2862 C  C    . ALA A 1 208 ? 40.37668  -10.43640 -7.69729  1.000 35.94131  ? 188 ALA A C    1 
ATOM   2863 O  O    . ALA A 1 208 ? 41.47042  -10.93231 -8.00914  1.000 39.15211  ? 188 ALA A O    1 
ATOM   2864 C  CB   . ALA A 1 208 ? 39.83889  -9.95907  -5.29286  1.000 40.55250  ? 188 ALA A CB   1 
ATOM   2865 H  H    . ALA A 1 208 ? 38.73367  -8.17504  -6.51363  1.000 43.99842  ? 188 ALA A H    1 
ATOM   2866 H  HA   . ALA A 1 208 ? 41.20131  -9.01269  -6.48054  1.000 46.23821  ? 188 ALA A HA   1 
ATOM   2867 H  HB1  . ALA A 1 208 ? 40.43635  -10.68083 -5.04184  1.000 48.68676  ? 188 ALA A HB1  1 
ATOM   2868 H  HB2  . ALA A 1 208 ? 39.85212  -9.26718  -4.61315  1.000 48.68676  ? 188 ALA A HB2  1 
ATOM   2869 H  HB3  . ALA A 1 208 ? 38.93689  -10.29893 -5.40140  1.000 48.68676  ? 188 ALA A HB3  1 
ATOM   2870 N  N    . THR A 1 209 ? 39.22903  -10.80152 -8.27480  1.000 37.42110  ? 189 THR A N    1 
ATOM   2871 C  CA   . THR A 1 209 ? 39.21112  -11.80419 -9.33670  1.000 40.44212  ? 189 THR A CA   1 
ATOM   2872 C  C    . THR A 1 209 ? 40.01154  -11.32466 -10.54212 1.000 39.43407  ? 189 THR A C    1 
ATOM   2873 O  O    . THR A 1 209 ? 40.84349  -12.06311 -11.07306 1.000 39.89750  ? 189 THR A O    1 
ATOM   2874 C  CB   . THR A 1 209 ? 37.77644  -12.13786 -9.75386  1.000 43.23048  ? 189 THR A CB   1 
ATOM   2875 O  OG1  . THR A 1 209 ? 37.00132  -12.58178 -8.63003  1.000 35.28951  ? 189 THR A OG1  1 
ATOM   2876 C  CG2  . THR A 1 209 ? 37.77796  -13.22112 -10.83435 1.000 39.54864  ? 189 THR A CG2  1 
ATOM   2877 H  H    . THR A 1 209 ? 38.45533  -10.48610 -8.07108  1.000 44.92908  ? 189 THR A H    1 
ATOM   2878 H  HA   . THR A 1 209 ? 39.61236  -12.61758 -8.99274  1.000 48.55430  ? 189 THR A HA   1 
ATOM   2879 H  HB   . THR A 1 209 ? 37.36144  -11.33695 -10.11052 1.000 51.90034  ? 189 THR A HB   1 
ATOM   2880 H  HG1  . THR A 1 209 ? 37.03145  -12.00925 -8.01611  1.000 42.37117  ? 189 THR A HG1  1 
ATOM   2881 H  HG21 . THR A 1 209 ? 36.88491  -13.58434 -10.94123 1.000 47.48213  ? 189 THR A HG21 1 
ATOM   2882 H  HG22 . THR A 1 209 ? 38.06838  -12.84557 -11.68023 1.000 47.48213  ? 189 THR A HG22 1 
ATOM   2883 H  HG23 . THR A 1 209 ? 38.38159  -13.93811 -10.58445 1.000 47.48213  ? 189 THR A HG23 1 
ATOM   2884 N  N    . ILE A 1 210 ? 39.75352  -10.08819 -10.99754 1.000 37.88775  ? 190 ILE A N    1 
ATOM   2885 C  CA   . ILE A 1 210 ? 40.52279  -9.49805  -12.09573 1.000 44.34163  ? 190 ILE A CA   1 
ATOM   2886 C  C    . ILE A 1 210 ? 42.01358  -9.60738  -11.83067 1.000 46.15800  ? 190 ILE A C    1 
ATOM   2887 O  O    . ILE A 1 210 ? 42.79074  -10.02861 -12.69965 1.000 46.45445  ? 190 ILE A O    1 
ATOM   2888 C  CB   . ILE A 1 210 ? 40.10215  -8.03120  -12.31195 1.000 42.88585  ? 190 ILE A CB   1 
ATOM   2889 C  CG1  . ILE A 1 210 ? 38.62729  -7.94920  -12.72852 1.000 42.38543  ? 190 ILE A CG1  1 
ATOM   2890 C  CG2  . ILE A 1 210 ? 40.98158  -7.36319  -13.35579 1.000 50.72940  ? 190 ILE A CG2  1 
ATOM   2891 C  CD1  . ILE A 1 210 ? 38.08865  -6.52655  -12.82246 1.000 43.45441  ? 190 ILE A CD1  1 
ATOM   2892 H  H    . ILE A 1 210 ? 39.13875  -9.57361  -10.68631 1.000 45.48906  ? 190 ILE A H    1 
ATOM   2893 H  HA   . ILE A 1 210 ? 40.32907  -9.99733  -12.90449 1.000 53.23371  ? 190 ILE A HA   1 
ATOM   2894 H  HB   . ILE A 1 210 ? 40.21447  -7.56269  -11.47006 1.000 51.48678  ? 190 ILE A HB   1 
ATOM   2895 H  HG12 . ILE A 1 210 ? 38.52715  -8.36093  -13.60108 1.000 50.88627  ? 190 ILE A HG12 1 
ATOM   2896 H  HG13 . ILE A 1 210 ? 38.09226  -8.42474  -12.07392 1.000 50.88627  ? 190 ILE A HG13 1 
ATOM   2897 H  HG21 . ILE A 1 210 ? 40.61075  -6.49312  -13.57115 1.000 60.89905  ? 190 ILE A HG21 1 
ATOM   2898 H  HG22 . ILE A 1 210 ? 41.87673  -7.26145  -12.99627 1.000 60.89905  ? 190 ILE A HG22 1 
ATOM   2899 H  HG23 . ILE A 1 210 ? 41.00553  -7.91852  -14.15074 1.000 60.89905  ? 190 ILE A HG23 1 
ATOM   2900 H  HD11 . ILE A 1 210 ? 37.12024  -6.55161  -12.77280 1.000 52.16906  ? 190 ILE A HD11 1 
ATOM   2901 H  HD12 . ILE A 1 210 ? 38.44424  -6.00496  -12.08598 1.000 52.16906  ? 190 ILE A HD12 1 
ATOM   2902 H  HD13 . ILE A 1 210 ? 38.36663  -6.13875  -13.66699 1.000 52.16906  ? 190 ILE A HD13 1 
ATOM   2903 N  N    . ALA A 1 211 ? 42.45511  -9.19312  -10.63857 1.000 42.39402  ? 191 ALA A N    1 
ATOM   2904 C  CA   . ALA A 1 211 ? 43.88738  -9.19410  -10.36028 1.000 47.10124  ? 191 ALA A CA   1 
ATOM   2905 C  C    . ALA A 1 211 ? 44.45863  -10.60619 -10.41810 1.000 48.14629  ? 191 ALA A C    1 
ATOM   2906 O  O    . ALA A 1 211 ? 45.56548  -10.82487 -10.94124 1.000 47.29890  ? 191 ALA A O    1 
ATOM   2907 C  CB   . ALA A 1 211 ? 44.16735  -8.57264  -8.98958  1.000 48.46133  ? 191 ALA A CB   1 
ATOM   2908 H  H    . ALA A 1 211 ? 41.95821  -8.91509  -9.99407  1.000 50.89659  ? 191 ALA A H    1 
ATOM   2909 H  HA   . ALA A 1 211 ? 44.32929  -8.65313  -11.03331 1.000 56.54524  ? 191 ALA A HA   1 
ATOM   2910 H  HB1  . ALA A 1 211 ? 45.12400  -8.57922  -8.82930  1.000 58.17736  ? 191 ALA A HB1  1 
ATOM   2911 H  HB2  . ALA A 1 211 ? 43.83712  -7.66061  -8.98293  1.000 58.17736  ? 191 ALA A HB2  1 
ATOM   2912 H  HB3  . ALA A 1 211 ? 43.71422  -9.09349  -8.30819  1.000 58.17736  ? 191 ALA A HB3  1 
ATOM   2913 N  N    . ALA A 1 212 ? 43.72277  -11.57449 -9.86667  1.000 45.55625  ? 192 ALA A N    1 
ATOM   2914 C  CA   . ALA A 1 212 ? 44.16547  -12.96411 -9.89054  1.000 48.08807  ? 192 ALA A CA   1 
ATOM   2915 C  C    . ALA A 1 212 ? 44.23245  -13.50365 -11.31354 1.000 45.98870  ? 192 ALA A C    1 
ATOM   2916 O  O    . ALA A 1 212 ? 45.18591  -14.20468 -11.67444 1.000 50.41046  ? 192 ALA A O    1 
ATOM   2917 C  CB   . ALA A 1 212 ? 43.22163  -13.82321 -9.03916  1.000 44.90822  ? 192 ALA A CB   1 
ATOM   2918 H  H    . ALA A 1 212 ? 42.96714  -11.45186 -9.47478  1.000 54.69126  ? 192 ALA A H    1 
ATOM   2919 H  HA   . ALA A 1 212 ? 45.05619  -13.01440 -9.50978  1.000 57.72944  ? 192 ALA A HA   1 
ATOM   2920 H  HB1  . ALA A 1 212 ? 43.53581  -14.74089 -9.04779  1.000 53.91363  ? 192 ALA A HB1  1 
ATOM   2921 H  HB2  . ALA A 1 212 ? 43.21834  -13.48325 -8.13069  1.000 53.91363  ? 192 ALA A HB2  1 
ATOM   2922 H  HB3  . ALA A 1 212 ? 42.32791  -13.77603 -9.41324  1.000 53.91363  ? 192 ALA A HB3  1 
ATOM   2923 N  N    . ARG A 1 213 ? 43.21772  -13.20295 -12.13781 1.000 45.62079  ? 193 ARG A N    1 
ATOM   2924 C  CA   . ARG A 1 213 ? 43.21715  -13.74501 -13.49006 1.000 46.75638  ? 193 ARG A CA   1 
ATOM   2925 C  C    . ARG A 1 213 ? 44.20501  -13.02918 -14.39863 1.000 50.73023  ? 193 ARG A C    1 
ATOM   2926 O  O    . ARG A 1 213 ? 44.72126  -13.64144 -15.33951 1.000 53.50191  ? 193 ARG A O    1 
ATOM   2927 C  CB   . ARG A 1 213 ? 41.82773  -13.66325 -14.10030 1.000 42.63931  ? 193 ARG A CB   1 
ATOM   2928 C  CG   . ARG A 1 213 ? 40.77061  -14.39204 -13.32611 1.000 43.20393  ? 193 ARG A CG   1 
ATOM   2929 C  CD   . ARG A 1 213 ? 41.06153  -15.86006 -13.17362 1.000 42.73733  ? 193 ARG A CD   1 
ATOM   2930 N  NE   . ARG A 1 213 ? 39.95978  -16.52855 -12.48278 1.000 47.98382  ? 193 ARG A NE   1 
ATOM   2931 C  CZ   . ARG A 1 213 ? 39.89606  -16.71823 -11.17266 1.000 41.40438  ? 193 ARG A CZ   1 
ATOM   2932 N  NH1  . ARG A 1 213 ? 40.90561  -16.40102 -10.37955 1.000 48.97665  ? 193 ARG A NH1  1 
ATOM   2933 N  NH2  . ARG A 1 213 ? 38.78424  -17.22642 -10.64343 1.000 48.95269  ? 193 ARG A NH2  1 
ATOM   2934 H  H    . ARG A 1 213 ? 42.54525  -12.70497 -11.93936 1.000 54.76871  ? 193 ARG A H    1 
ATOM   2935 H  HA   . ARG A 1 213 ? 43.46988  -14.67990 -13.43534 1.000 56.13141  ? 193 ARG A HA   1 
ATOM   2936 H  HB2  . ARG A 1 213 ? 41.56548  -12.73068 -14.14974 1.000 51.19093  ? 193 ARG A HB2  1 
ATOM   2937 H  HB3  . ARG A 1 213 ? 41.85731  -14.04720 -14.99059 1.000 51.19093  ? 193 ARG A HB3  1 
ATOM   2938 H  HG2  . ARG A 1 213 ? 40.70722  -14.00641 -12.43832 1.000 51.86848  ? 193 ARG A HG2  1 
ATOM   2939 H  HG3  . ARG A 1 213 ? 39.92250  -14.30214 -13.78820 1.000 51.86848  ? 193 ARG A HG3  1 
ATOM   2940 H  HD2  . ARG A 1 213 ? 41.16814  -16.26329 -14.04937 1.000 51.30855  ? 193 ARG A HD2  1 
ATOM   2941 H  HD3  . ARG A 1 213 ? 41.87123  -15.97889 -12.65287 1.000 51.30855  ? 193 ARG A HD3  1 
ATOM   2942 H  HE   . ARG A 1 213 ? 39.30657  -16.81936 -12.96065 1.000 57.60434  ? 193 ARG A HE   1 
ATOM   2943 H  HH11 . ARG A 1 213 ? 41.62366  -16.06364 -10.71150 1.000 58.79575  ? 193 ARG A HH11 1 
ATOM   2944 H  HH12 . ARG A 1 213 ? 40.84410  -16.53211 -9.53183  1.000 58.79575  ? 193 ARG A HH12 1 
ATOM   2945 H  HH21 . ARG A 1 213 ? 38.11932  -17.42701 -11.15062 1.000 58.76699  ? 193 ARG A HH21 1 
ATOM   2946 H  HH22 . ARG A 1 213 ? 38.73138  -17.35392 -9.79458  1.000 58.76699  ? 193 ARG A HH22 1 
ATOM   2947 N  N    . ARG A 1 214 ? 44.48379  -11.74839 -14.13854 1.000 51.99862  ? 194 ARG A N    1 
ATOM   2948 C  CA   . ARG A 1 214 ? 45.55825  -11.08443 -14.86745 1.000 59.11996  ? 194 ARG A CA   1 
ATOM   2949 C  C    . ARG A 1 214 ? 46.90679  -11.72878 -14.58701 1.000 51.02564  ? 194 ARG A C    1 
ATOM   2950 O  O    . ARG A 1 214 ? 47.79218  -11.69407 -15.44574 1.000 57.62177  ? 194 ARG A O    1 
ATOM   2951 C  CB   . ARG A 1 214 ? 45.60847  -9.59471  -14.52531 1.000 59.77174  ? 194 ARG A CB   1 
ATOM   2952 C  CG   . ARG A 1 214 ? 44.62723  -8.75382  -15.32187 1.000 66.23049  ? 194 ARG A CG   1 
ATOM   2953 C  CD   . ARG A 1 214 ? 44.67780  -7.28209  -14.92484 1.000 60.36835  ? 194 ARG A CD   1 
ATOM   2954 N  NE   . ARG A 1 214 ? 43.56867  -6.52824  -15.50272 1.000 59.86975  ? 194 ARG A NE   1 
ATOM   2955 C  CZ   . ARG A 1 214 ? 43.44029  -6.26582  -16.79585 1.000 52.63392  ? 194 ARG A CZ   1 
ATOM   2956 N  NH1  . ARG A 1 214 ? 44.32798  -6.69787  -17.67703 1.000 68.33731  ? 194 ARG A NH1  1 
ATOM   2957 N  NH2  . ARG A 1 214 ? 42.40075  -5.54847  -17.21552 1.000 55.26959  ? 194 ARG A NH2  1 
ATOM   2958 H  H    . ARG A 1 214 ? 44.07616  -11.25824 -13.56130 1.000 62.42211  ? 194 ARG A H    1 
ATOM   2959 H  HA   . ARG A 1 214 ? 45.37186  -11.16283 -15.81614 1.000 70.96772  ? 194 ARG A HA   1 
ATOM   2960 H  HB2  . ARG A 1 214 ? 45.39944  -9.48314  -13.58470 1.000 71.74985  ? 194 ARG A HB2  1 
ATOM   2961 H  HB3  . ARG A 1 214 ? 46.50109  -9.26218  -14.70851 1.000 71.74985  ? 194 ARG A HB3  1 
ATOM   2962 H  HG2  . ARG A 1 214 ? 44.84296  -8.81995  -16.26526 1.000 79.50034  ? 194 ARG A HG2  1 
ATOM   2963 H  HG3  . ARG A 1 214 ? 43.72704  -9.07875  -15.16382 1.000 79.50034  ? 194 ARG A HG3  1 
ATOM   2964 H  HD2  . ARG A 1 214 ? 44.62482  -7.20890  -13.95906 1.000 72.46579  ? 194 ARG A HD2  1 
ATOM   2965 H  HD3  . ARG A 1 214 ? 45.50788  -6.89314  -15.24199 1.000 72.46579  ? 194 ARG A HD3  1 
ATOM   2966 H  HE   . ARG A 1 214 ? 42.95994  -6.23585  -14.97023 1.000 71.86746  ? 194 ARG A HE   1 
ATOM   2967 H  HH11 . ARG A 1 214 ? 45.00497  -7.15884  -17.41477 1.000 82.02853  ? 194 ARG A HH11 1 
ATOM   2968 H  HH12 . ARG A 1 214 ? 44.22789  -6.51766  -18.51196 1.000 82.02853  ? 194 ARG A HH12 1 
ATOM   2969 H  HH21 . ARG A 1 214 ? 41.82073  -5.26022  -16.64976 1.000 66.34728  ? 194 ARG A HH21 1 
ATOM   2970 H  HH22 . ARG A 1 214 ? 42.30906  -5.37318  -18.05246 1.000 66.34728  ? 194 ARG A HH22 1 
ATOM   2971 N  N    . ALA A 1 215 ? 47.08680  -12.32585 -13.40544 1.000 60.30221  ? 195 ALA A N    1 
ATOM   2972 C  CA   . ALA A 1 215 ? 48.35562  -12.96047 -13.05872 1.000 59.82135  ? 195 ALA A CA   1 
ATOM   2973 C  C    . ALA A 1 215 ? 48.38832  -14.44373 -13.41473 1.000 63.74642  ? 195 ALA A C    1 
ATOM   2974 O  O    . ALA A 1 215 ? 49.41559  -14.93806 -13.88889 1.000 56.38619  ? 195 ALA A O    1 
ATOM   2975 C  CB   . ALA A 1 215 ? 48.65490  -12.79585 -11.56434 1.000 58.05920  ? 195 ALA A CB   1 
ATOM   2976 H  H    . ALA A 1 215 ? 46.48846  -12.37549 -12.78970 1.000 72.38642  ? 195 ALA A H    1 
ATOM   2977 H  HA   . ALA A 1 215 ? 49.05619  -12.51149 -13.55724 1.000 71.80938  ? 195 ALA A HA   1 
ATOM   2978 H  HB1  . ALA A 1 215 ? 49.50756  -13.21322 -11.36518 1.000 69.69480  ? 195 ALA A HB1  1 
ATOM   2979 H  HB2  . ALA A 1 215 ? 48.69195  -11.85010 -11.35199 1.000 69.69480  ? 195 ALA A HB2  1 
ATOM   2980 H  HB3  . ALA A 1 215 ? 47.95016  -13.22248 -11.05225 1.000 69.69480  ? 195 ALA A HB3  1 
ATOM   2981 N  N    . ASP A 1 216 ? 47.29259  -15.16765 -13.18807 1.000 54.85985  ? 196 ASP A N    1 
ATOM   2982 C  CA   . ASP A 1 216 ? 47.18290  -16.59118 -13.51902 1.000 59.83260  ? 196 ASP A CA   1 
ATOM   2983 C  C    . ASP A 1 216 ? 45.84922  -16.77149 -14.24298 1.000 54.41848  ? 196 ASP A C    1 
ATOM   2984 O  O    . ASP A 1 216 ? 44.82226  -17.11480 -13.63429 1.000 49.78963  ? 196 ASP A O    1 
ATOM   2985 C  CB   . ASP A 1 216 ? 47.31057  -17.46582 -12.26912 1.000 58.29211  ? 196 ASP A CB   1 
ATOM   2986 H  H    . ASP A 1 216 ? 46.57778  -14.84758 -12.83282 1.000 65.85559  ? 196 ASP A H    1 
ATOM   2987 H  HA   . ASP A 1 216 ? 47.89465  -16.86430 -14.11879 1.000 71.82288  ? 196 ASP A HA   1 
ATOM   2988 N  N    . PRO A 1 217 ? 45.82413  -16.51268 -15.55131 1.000 51.74835  ? 197 PRO A N    1 
ATOM   2989 C  CA   . PRO A 1 217 ? 44.57040  -16.65381 -16.30885 1.000 57.85469  ? 197 PRO A CA   1 
ATOM   2990 C  C    . PRO A 1 217 ? 44.06607  -18.09090 -16.30229 1.000 51.69742  ? 197 PRO A C    1 
ATOM   2991 O  O    . PRO A 1 217 ? 44.84825  -19.04366 -16.35942 1.000 51.33261  ? 197 PRO A O    1 
ATOM   2992 C  CB   . PRO A 1 217 ? 44.94512  -16.21288 -17.72995 1.000 55.39960  ? 197 PRO A CB   1 
ATOM   2993 C  CG   . PRO A 1 217 ? 46.32031  -15.68247 -17.67801 1.000 56.16808  ? 197 PRO A CG   1 
ATOM   2994 C  CD   . PRO A 1 217 ? 46.92867  -15.93758 -16.34382 1.000 59.00333  ? 197 PRO A CD   1 
ATOM   2995 H  HA   . PRO A 1 217 ? 43.89472  -16.06154 -15.94337 1.000 69.44938  ? 197 PRO A HA   1 
ATOM   2996 H  HB2  . PRO A 1 217 ? 44.89950  -16.97741 -18.32519 1.000 66.50329  ? 197 PRO A HB2  1 
ATOM   2997 H  HB3  . PRO A 1 217 ? 44.32805  -15.52520 -18.02528 1.000 66.50329  ? 197 PRO A HB3  1 
ATOM   2998 H  HG2  . PRO A 1 217 ? 46.84556  -16.12152 -18.36520 1.000 67.42546  ? 197 PRO A HG2  1 
ATOM   2999 H  HG3  . PRO A 1 217 ? 46.28818  -14.72740 -17.84447 1.000 67.42546  ? 197 PRO A HG3  1 
ATOM   3000 H  HD2  . PRO A 1 217 ? 47.66222  -16.56803 -16.41681 1.000 70.82776  ? 197 PRO A HD2  1 
ATOM   3001 H  HD3  . PRO A 1 217 ? 47.24091  -15.10990 -15.94589 1.000 70.82776  ? 197 PRO A HD3  1 
ATOM   3002 N  N    . THR A 1 218 ? 42.74206  -18.23316 -16.25916 1.000 47.14890  ? 198 THR A N    1 
ATOM   3003 C  CA   . THR A 1 218 ? 42.07551  -19.52386 -16.35154 1.000 48.79092  ? 198 THR A CA   1 
ATOM   3004 C  C    . THR A 1 218 ? 41.11697  -19.48156 -17.53586 1.000 49.37095  ? 198 THR A C    1 
ATOM   3005 O  O    . THR A 1 218 ? 41.31938  -18.69768 -18.47064 1.000 50.51356  ? 198 THR A O    1 
ATOM   3006 C  CB   . THR A 1 218 ? 41.33988  -19.84913 -15.05518 1.000 42.81977  ? 198 THR A CB   1 
ATOM   3007 O  OG1  . THR A 1 218 ? 40.25000  -18.93258 -14.87703 1.000 47.05484  ? 198 THR A OG1  1 
ATOM   3008 C  CG2  . THR A 1 218 ? 42.28472  -19.77332 -13.86315 1.000 49.32337  ? 198 THR A CG2  1 
ATOM   3009 H  H    . THR A 1 218 ? 42.19375  -17.57609 -16.17428 1.000 56.60244  ? 198 THR A H    1 
ATOM   3010 H  HA   . THR A 1 218 ? 42.72078  -20.23567 -16.48513 1.000 58.57287  ? 198 THR A HA   1 
ATOM   3011 H  HB   . THR A 1 218 ? 40.99074  -20.75307 -15.09869 1.000 51.40749  ? 198 THR A HB   1 
ATOM   3012 H  HG1  . THR A 1 218 ? 39.81619  -19.13285 -14.18616 1.000 56.48957  ? 198 THR A HG1  1 
ATOM   3013 H  HG21 . THR A 1 218 ? 41.81270  -20.01177 -13.04998 1.000 59.21180  ? 198 THR A HG21 1 
ATOM   3014 H  HG22 . THR A 1 218 ? 43.02615  -20.38617 -13.98799 1.000 59.21180  ? 198 THR A HG22 1 
ATOM   3015 H  HG23 . THR A 1 218 ? 42.63277  -18.87247 -13.77246 1.000 59.21180  ? 198 THR A HG23 1 
ATOM   3016 N  N    . ASP A 1 219 ? 40.07250  -20.30672 -17.51998 1.000 51.86118  ? 199 ASP A N    1 
ATOM   3017 C  CA   . ASP A 1 219 ? 39.09190  -20.29710 -18.60117 1.000 54.14731  ? 199 ASP A CA   1 
ATOM   3018 C  C    . ASP A 1 219 ? 37.73603  -19.76000 -18.16144 1.000 50.14246  ? 199 ASP A C    1 
ATOM   3019 O  O    . ASP A 1 219 ? 36.73528  -19.99666 -18.84424 1.000 52.56580  ? 199 ASP A O    1 
ATOM   3020 C  CB   . ASP A 1 219 ? 38.92429  -21.69917 -19.19132 1.000 66.17225  ? 199 ASP A CB   1 
ATOM   3021 C  CG   . ASP A 1 219 ? 38.35357  -21.67899 -20.60469 1.000 67.95135  ? 199 ASP A CG   1 
ATOM   3022 O  OD1  . ASP A 1 219 ? 38.13614  -20.57821 -21.15236 1.000 67.96916  ? 199 ASP A OD1  1 
ATOM   3023 O  OD2  . ASP A 1 219 ? 38.10564  -22.76885 -21.16465 1.000 75.49944  ? 199 ASP A OD2  1 
ATOM   3024 H  H    . ASP A 1 219 ? 39.91206  -20.87749 -16.89702 1.000 62.25718  ? 199 ASP A H    1 
ATOM   3025 H  HA   . ASP A 1 219 ? 39.43071  -19.71296 -19.29751 1.000 65.00053  ? 199 ASP A HA   1 
ATOM   3026 H  HB2  . ASP A 1 219 ? 39.79065  -22.13423 -19.22376 1.000 79.43046  ? 199 ASP A HB2  1 
ATOM   3027 H  HB3  . ASP A 1 219 ? 38.31832  -22.20802 -18.63028 1.000 79.43046  ? 199 ASP A HB3  1 
ATOM   3028 N  N    . ASP A 1 220 ? 37.68465  -19.01862 -17.05889 1.000 43.35494  ? 200 ASP A N    1 
ATOM   3029 C  CA   . ASP A 1 220 ? 36.43087  -18.48474 -16.56459 1.000 42.53779  ? 200 ASP A CA   1 
ATOM   3030 C  C    . ASP A 1 220 ? 36.13099  -17.15530 -17.25304 1.000 37.07492  ? 200 ASP A C    1 
ATOM   3031 O  O    . ASP A 1 220 ? 36.88173  -16.68716 -18.11838 1.000 36.90131  ? 200 ASP A O    1 
ATOM   3032 C  CB   . ASP A 1 220 ? 36.45750  -18.35115 -15.04047 1.000 38.23182  ? 200 ASP A CB   1 
ATOM   3033 C  CG   . ASP A 1 220 ? 37.38443  -17.26460 -14.53417 1.000 42.82873  ? 200 ASP A CG   1 
ATOM   3034 O  OD1  . ASP A 1 220 ? 38.13126  -16.64909 -15.32135 1.000 44.08041  ? 200 ASP A OD1  1 
ATOM   3035 O  OD2  . ASP A 1 220 ? 37.37522  -17.04253 -13.30400 1.000 46.44174  ? 200 ASP A OD2  1 
ATOM   3036 H  H    . ASP A 1 220 ? 38.36869  -18.81238 -16.58018 1.000 52.04969  ? 200 ASP A H    1 
ATOM   3037 H  HA   . ASP A 1 220 ? 35.71698  -19.10448 -16.78182 1.000 51.06911  ? 200 ASP A HA   1 
ATOM   3038 H  HB2  . ASP A 1 220 ? 35.56227  -18.14309 -14.73036 1.000 45.90194  ? 200 ASP A HB2  1 
ATOM   3039 H  HB3  . ASP A 1 220 ? 36.75351  -19.19251 -14.65918 1.000 45.90194  ? 200 ASP A HB3  1 
ATOM   3040 N  N    . LEU A 1 221 ? 34.99197  -16.56845 -16.88959 1.000 35.94319  ? 201 LEU A N    1 
ATOM   3041 C  CA   . LEU A 1 221 ? 34.48524  -15.41174 -17.61372 1.000 30.87811  ? 201 LEU A CA   1 
ATOM   3042 C  C    . LEU A 1 221 ? 35.40203  -14.20868 -17.46361 1.000 34.10373  ? 201 LEU A C    1 
ATOM   3043 O  O    . LEU A 1 221 ? 35.65466  -13.50343 -18.44257 1.000 32.90451  ? 201 LEU A O    1 
ATOM   3044 C  CB   . LEU A 1 221 ? 33.07080  -15.07594 -17.12617 1.000 30.35144  ? 201 LEU A CB   1 
ATOM   3045 C  CG   . LEU A 1 221 ? 32.47788  -13.84171 -17.81061 1.000 28.74438  ? 201 LEU A CG   1 
ATOM   3046 C  CD1  . LEU A 1 221 ? 32.35084  -14.03681 -19.28700 1.000 27.91731  ? 201 LEU A CD1  1 
ATOM   3047 C  CD2  . LEU A 1 221 ? 31.08351  -13.54070 -17.19513 1.000 34.24706  ? 201 LEU A CD2  1 
ATOM   3048 H  H    . LEU A 1 221 ? 34.49835  -16.81994 -16.23181 1.000 43.15559  ? 201 LEU A H    1 
ATOM   3049 H  HA   . LEU A 1 221 ? 34.44071  -15.63028 -18.55773 1.000 37.07750  ? 201 LEU A HA   1 
ATOM   3050 H  HB2  . LEU A 1 221 ? 32.48829  -15.82946 -17.30999 1.000 36.44549  ? 201 LEU A HB2  1 
ATOM   3051 H  HB3  . LEU A 1 221 ? 33.10020  -14.90439 -16.17191 1.000 36.44549  ? 201 LEU A HB3  1 
ATOM   3052 H  HG   . LEU A 1 221 ? 33.07144  -13.08749 -17.67010 1.000 34.51702  ? 201 LEU A HG   1 
ATOM   3053 H  HD11 . LEU A 1 221 ? 31.88758  -13.27430 -19.66761 1.000 33.52453  ? 201 LEU A HD11 1 
ATOM   3054 H  HD12 . LEU A 1 221 ? 33.23753  -14.11163 -19.67312 1.000 33.52453  ? 201 LEU A HD12 1 
ATOM   3055 H  HD13 . LEU A 1 221 ? 31.84689  -14.84819 -19.45612 1.000 33.52453  ? 201 LEU A HD13 1 
ATOM   3056 H  HD21 . LEU A 1 221 ? 30.70296  -12.76655 -17.63872 1.000 41.12024  ? 201 LEU A HD21 1 
ATOM   3057 H  HD22 . LEU A 1 221 ? 30.50860  -14.31135 -17.32355 1.000 41.12024  ? 201 LEU A HD22 1 
ATOM   3058 H  HD23 . LEU A 1 221 ? 31.18866  -13.36066 -16.24781 1.000 41.12024  ? 201 LEU A HD23 1 
ATOM   3059 N  N    . VAL A 1 222 ? 35.88141  -13.92969 -16.24980 1.000 31.93834  ? 202 VAL A N    1 
ATOM   3060 C  CA   . VAL A 1 222 ? 36.77454  -12.78516 -16.08744 1.000 32.71716  ? 202 VAL A CA   1 
ATOM   3061 C  C    . VAL A 1 222 ? 38.03355  -12.99043 -16.93040 1.000 33.75054  ? 202 VAL A C    1 
ATOM   3062 O  O    . VAL A 1 222 ? 38.55769  -12.03988 -17.53166 1.000 35.78632  ? 202 VAL A O    1 
ATOM   3063 C  CB   . VAL A 1 222 ? 37.10419  -12.52980 -14.60114 1.000 32.18706  ? 202 VAL A CB   1 
ATOM   3064 C  CG1  . VAL A 1 222 ? 38.23238  -11.51354 -14.48231 1.000 36.09201  ? 202 VAL A CG1  1 
ATOM   3065 C  CG2  . VAL A 1 222 ? 35.82879  -12.04727 -13.86857 1.000 37.23282  ? 202 VAL A CG2  1 
ATOM   3066 H  H    . VAL A 1 222 ? 35.71085  -14.37120 -15.53176 1.000 38.34977  ? 202 VAL A H    1 
ATOM   3067 H  HA   . VAL A 1 222 ? 36.31625  -11.99223 -16.40703 1.000 39.28436  ? 202 VAL A HA   1 
ATOM   3068 H  HB   . VAL A 1 222 ? 37.40513  -13.34972 -14.17916 1.000 38.64823  ? 202 VAL A HB   1 
ATOM   3069 H  HG11 . VAL A 1 222 ? 38.24552  -11.16047 -13.57894 1.000 43.33417  ? 202 VAL A HG11 1 
ATOM   3070 H  HG12 . VAL A 1 222 ? 39.07485  -11.95261 -14.67814 1.000 43.33417  ? 202 VAL A HG12 1 
ATOM   3071 H  HG13 . VAL A 1 222 ? 38.07853  -10.79538 -15.11593 1.000 43.33417  ? 202 VAL A HG13 1 
ATOM   3072 H  HG21 . VAL A 1 222 ? 36.02039  -11.96613 -12.92114 1.000 44.70314  ? 202 VAL A HG21 1 
ATOM   3073 H  HG22 . VAL A 1 222 ? 35.56521  -11.18563 -14.22771 1.000 44.70314  ? 202 VAL A HG22 1 
ATOM   3074 H  HG23 . VAL A 1 222 ? 35.12019  -12.69473 -14.00847 1.000 44.70314  ? 202 VAL A HG23 1 
ATOM   3075 N  N    . SER A 1 223 ? 38.55966  -14.22916 -16.96778 1.000 35.14307  ? 203 SER A N    1 
ATOM   3076 C  CA   . SER A 1 223 ? 39.75340  -14.48621 -17.76883 1.000 36.12569  ? 203 SER A CA   1 
ATOM   3077 C  C    . SER A 1 223 ? 39.50147  -14.17359 -19.23784 1.000 33.67141  ? 203 SER A C    1 
ATOM   3078 O  O    . SER A 1 223 ? 40.36668  -13.59618 -19.91264 1.000 37.42322  ? 203 SER A O    1 
ATOM   3079 C  CB   . SER A 1 223 ? 40.19451  -15.94675 -17.62081 1.000 40.76827  ? 203 SER A CB   1 
ATOM   3080 O  OG   . SER A 1 223 ? 40.65464  -16.22042 -16.31890 1.000 41.31213  ? 203 SER A OG   1 
ATOM   3081 H  H    . SER A 1 223 ? 38.24882  -14.91277 -16.54867 1.000 42.19545  ? 203 SER A H    1 
ATOM   3082 H  HA   . SER A 1 223 ? 40.46851  -13.91751 -17.44311 1.000 43.37459  ? 203 SER A HA   1 
ATOM   3083 H  HB2  . SER A 1 223 ? 39.43795  -16.52275 -17.81251 1.000 48.94569  ? 203 SER A HB2  1 
ATOM   3084 H  HB3  . SER A 1 223 ? 40.91234  -16.12173 -18.24930 1.000 48.94569  ? 203 SER A HB3  1 
ATOM   3085 H  HG   . SER A 1 223 ? 40.02235  -16.15124 -15.77025 1.000 49.59831  ? 203 SER A HG   1 
ATOM   3086 N  N    . VAL A 1 224 ? 38.34830  -14.59832 -19.76135 1.000 37.76251  ? 204 VAL A N    1 
ATOM   3087 C  CA   . VAL A 1 224 ? 38.03846  -14.35452 -21.16751 1.000 36.72084  ? 204 VAL A CA   1 
ATOM   3088 C  C    . VAL A 1 224 ? 37.86379  -12.86606 -21.42015 1.000 38.17362  ? 204 VAL A C    1 
ATOM   3089 O  O    . VAL A 1 224 ? 38.28705  -12.33896 -22.45428 1.000 37.46320  ? 204 VAL A O    1 
ATOM   3090 C  CB   . VAL A 1 224 ? 36.78212  -15.14835 -21.56971 1.000 41.40214  ? 204 VAL A CB   1 
ATOM   3091 C  CG1  . VAL A 1 224 ? 36.19249  -14.62468 -22.87280 1.000 44.09085  ? 204 VAL A CG1  1 
ATOM   3092 C  CG2  . VAL A 1 224 ? 37.12050  -16.62903 -21.68178 1.000 44.21718  ? 204 VAL A CG2  1 
ATOM   3093 H  H    . VAL A 1 224 ? 37.73850  -15.02350 -19.32896 1.000 45.33877  ? 204 VAL A H    1 
ATOM   3094 H  HA   . VAL A 1 224 ? 38.78048  -14.66314 -21.71071 1.000 44.08876  ? 204 VAL A HA   1 
ATOM   3095 H  HB   . VAL A 1 224 ? 36.10574  -15.03579 -20.88361 1.000 49.70634  ? 204 VAL A HB   1 
ATOM   3096 H  HG11 . VAL A 1 224 ? 35.57127  -15.28129 -23.22470 1.000 52.93278  ? 204 VAL A HG11 1 
ATOM   3097 H  HG12 . VAL A 1 224 ? 35.72846  -13.79121 -22.69701 1.000 52.93278  ? 204 VAL A HG12 1 
ATOM   3098 H  HG13 . VAL A 1 224 ? 36.91100  -14.47580 -23.50721 1.000 52.93278  ? 204 VAL A HG13 1 
ATOM   3099 H  HG21 . VAL A 1 224 ? 36.49134  -17.05183 -22.28700 1.000 53.08438  ? 204 VAL A HG21 1 
ATOM   3100 H  HG22 . VAL A 1 224 ? 38.02297  -16.72163 -22.02512 1.000 53.08438  ? 204 VAL A HG22 1 
ATOM   3101 H  HG23 . VAL A 1 224 ? 37.05770  -17.03473 -20.80294 1.000 53.08438  ? 204 VAL A HG23 1 
ATOM   3102 N  N    . LEU A 1 225 ? 37.20967  -12.16711 -20.49605 1.000 33.35090  ? 205 LEU A N    1 
ATOM   3103 C  CA   . LEU A 1 225 ? 36.96680  -10.74888 -20.70195 1.000 33.48471  ? 205 LEU A CA   1 
ATOM   3104 C  C    . LEU A 1 225 ? 38.25367  -9.94674  -20.59663 1.000 37.53611  ? 205 LEU A C    1 
ATOM   3105 O  O    . LEU A 1 225 ? 38.45426  -8.98087  -21.34493 1.000 37.48173  ? 205 LEU A O    1 
ATOM   3106 C  CB   . LEU A 1 225 ? 35.93724  -10.26539 -19.69164 1.000 29.97143  ? 205 LEU A CB   1 
ATOM   3107 C  CG   . LEU A 1 225 ? 34.54183  -10.80099 -19.93675 1.000 28.85133  ? 205 LEU A CG   1 
ATOM   3108 C  CD1  . LEU A 1 225 ? 33.58066  -10.26033 -18.85781 1.000 31.00182  ? 205 LEU A CD1  1 
ATOM   3109 C  CD2  . LEU A 1 225 ? 33.95720  -10.46035 -21.32183 1.000 31.59376  ? 205 LEU A CD2  1 
ATOM   3110 H  H    . LEU A 1 225 ? 36.90362  -12.48524 -19.75799 1.000 40.04484  ? 205 LEU A H    1 
ATOM   3111 H  HA   . LEU A 1 225 ? 36.60964  -10.60779 -21.59269 1.000 40.20542  ? 205 LEU A HA   1 
ATOM   3112 H  HB2  . LEU A 1 225 ? 36.21289  -10.55002 -18.80625 1.000 35.98947  ? 205 LEU A HB2  1 
ATOM   3113 H  HB3  . LEU A 1 225 ? 35.89433  -9.29712  -19.73046 1.000 35.98947  ? 205 LEU A HB3  1 
ATOM   3114 H  HG   . LEU A 1 225 ? 34.61633  -11.76741 -19.89958 1.000 34.64536  ? 205 LEU A HG   1 
ATOM   3115 H  HD11 . LEU A 1 225 ? 32.69175  -10.61227 -19.02176 1.000 37.22595  ? 205 LEU A HD11 1 
ATOM   3116 H  HD12 . LEU A 1 225 ? 33.89338  -10.54517 -17.98490 1.000 37.22595  ? 205 LEU A HD12 1 
ATOM   3117 H  HD13 . LEU A 1 225 ? 33.56660  -9.29154  -18.90422 1.000 37.22595  ? 205 LEU A HD13 1 
ATOM   3118 H  HD21 . LEU A 1 225 ? 32.99573  -10.58663 -21.29852 1.000 37.93628  ? 205 LEU A HD21 1 
ATOM   3119 H  HD22 . LEU A 1 225 ? 34.16447  -9.53673  -21.53364 1.000 37.93628  ? 205 LEU A HD22 1 
ATOM   3120 H  HD23 . LEU A 1 225 ? 34.35207  -11.04834 -21.98458 1.000 37.93628  ? 205 LEU A HD23 1 
ATOM   3121 N  N    . VAL A 1 226 ? 39.14598  -10.33744 -19.69006 1.000 38.37250  ? 206 VAL A N    1 
ATOM   3122 C  CA   . VAL A 1 226 ? 40.41174  -9.62216  -19.55907 1.000 38.34383  ? 206 VAL A CA   1 
ATOM   3123 C  C    . VAL A 1 226 ? 41.21831  -9.70902  -20.83907 1.000 40.14284  ? 206 VAL A C    1 
ATOM   3124 O  O    . VAL A 1 226 ? 41.94222  -8.77079  -21.18513 1.000 43.96726  ? 206 VAL A O    1 
ATOM   3125 C  CB   . VAL A 1 226 ? 41.22966  -10.15062 -18.36124 1.000 39.53911  ? 206 VAL A CB   1 
ATOM   3126 C  CG1  . VAL A 1 226 ? 42.73034  -9.91036  -18.56015 1.000 48.71090  ? 206 VAL A CG1  1 
ATOM   3127 C  CG2  . VAL A 1 226 ? 40.68366  -9.51863  -17.07262 1.000 37.05578  ? 206 VAL A CG2  1 
ATOM   3128 H  H    . VAL A 1 226 ? 39.04565  -10.99915 -19.15000 1.000 46.07076  ? 206 VAL A H    1 
ATOM   3129 H  HA   . VAL A 1 226 ? 40.20161  -8.69058  -19.38904 1.000 46.03636  ? 206 VAL A HA   1 
ATOM   3130 H  HB   . VAL A 1 226 ? 41.13473  -11.11299 -18.28550 1.000 47.47069  ? 206 VAL A HB   1 
ATOM   3131 H  HG11 . VAL A 1 226 ? 43.18654  -10.04536 -17.71484 1.000 58.47685  ? 206 VAL A HG11 1 
ATOM   3132 H  HG12 . VAL A 1 226 ? 43.06560  -10.53661 -19.22068 1.000 58.47685  ? 206 VAL A HG12 1 
ATOM   3133 H  HG13 . VAL A 1 226 ? 42.86644  -9.00059  -18.86787 1.000 58.47685  ? 206 VAL A HG13 1 
ATOM   3134 H  HG21 . VAL A 1 226 ? 41.18691  -9.85866  -16.31630 1.000 44.49070  ? 206 VAL A HG21 1 
ATOM   3135 H  HG22 . VAL A 1 226 ? 40.78030  -8.55504  -17.12794 1.000 44.49070  ? 206 VAL A HG22 1 
ATOM   3136 H  HG23 . VAL A 1 226 ? 39.74693  -9.75227  -16.97861 1.000 44.49070  ? 206 VAL A HG23 1 
ATOM   3137 N  N    . SER A 1 227 ? 41.12543  -10.82646 -21.55802 1.000 41.68084  ? 207 SER A N    1 
ATOM   3138 C  CA   . SER A 1 227 ? 41.91434  -11.03351 -22.76661 1.000 46.39966  ? 207 SER A CA   1 
ATOM   3139 C  C    . SER A 1 227 ? 41.23501  -10.52490 -24.02928 1.000 44.08686  ? 207 SER A C    1 
ATOM   3140 O  O    . SER A 1 227 ? 41.90497  -10.43301 -25.07521 1.000 43.98969  ? 207 SER A O    1 
ATOM   3141 C  CB   . SER A 1 227 ? 42.22389  -12.52352 -22.93658 1.000 49.98833  ? 207 SER A CB   1 
ATOM   3142 O  OG   . SER A 1 227 ? 43.14672  -12.95253 -21.95113 1.000 68.40411  ? 207 SER A OG   1 
ATOM   3143 H  H    . SER A 1 227 ? 40.60725  -11.48458 -21.36315 1.000 50.04077  ? 207 SER A H    1 
ATOM   3144 H  HA   . SER A 1 227 ? 42.75148  -10.55325 -22.66948 1.000 55.70335  ? 207 SER A HA   1 
ATOM   3145 H  HB2  . SER A 1 227 ? 41.40233  -13.03090 -22.84436 1.000 60.00976  ? 207 SER A HB2  1 
ATOM   3146 H  HB3  . SER A 1 227 ? 42.60726  -12.66979 -23.81552 1.000 60.00976  ? 207 SER A HB3  1 
ATOM   3147 H  HG   . SER A 1 227 ? 43.30309  -13.77286 -22.04169 1.000 82.10870  ? 207 SER A HG   1 
ATOM   3148 N  N    . SER A 1 228 ? 39.94758  -10.17139 -23.94614 1.000 37.89896  ? 208 SER A N    1 
ATOM   3149 C  CA   . SER A 1 228 ? 39.19503  -9.74768  -25.11709 1.000 34.99506  ? 208 SER A CA   1 
ATOM   3150 C  C    . SER A 1 228 ? 39.79324  -8.46904  -25.69805 1.000 38.72236  ? 208 SER A C    1 
ATOM   3151 O  O    . SER A 1 228 ? 40.12757  -7.53266  -24.97220 1.000 39.14796  ? 208 SER A O    1 
ATOM   3152 C  CB   . SER A 1 228 ? 37.73025  -9.54352  -24.72431 1.000 33.73677  ? 208 SER A CB   1 
ATOM   3153 O  OG   . SER A 1 228 ? 36.97540  -9.22576  -25.84804 1.000 35.62750  ? 208 SER A OG   1 
ATOM   3154 H  H    . SER A 1 228 ? 39.48997  -10.17009 -23.21800 1.000 45.50251  ? 208 SER A H    1 
ATOM   3155 H  HA   . SER A 1 228 ? 39.23373  -10.42767 -25.80775 1.000 42.01783  ? 208 SER A HA   1 
ATOM   3156 H  HB2  . SER A 1 228 ? 37.38837  -10.36182 -24.33137 1.000 40.50789  ? 208 SER A HB2  1 
ATOM   3157 H  HB3  . SER A 1 228 ? 37.66998  -8.81753  -24.08385 1.000 40.50789  ? 208 SER A HB3  1 
ATOM   3158 H  HG   . SER A 1 228 ? 36.17192  -9.11130  -25.63144 1.000 42.77676  ? 208 SER A HG   1 
ATOM   3159 N  N    . GLU A 1 229 ? 39.94086  -8.43349  -27.01565 1.000 36.75062  ? 209 GLU A N    1 
ATOM   3160 C  CA   . GLU A 1 229 ? 40.53635  -7.29084  -27.68699 1.000 39.43472  ? 209 GLU A CA   1 
ATOM   3161 C  C    . GLU A 1 229 ? 39.79286  -7.04514  -28.99033 1.000 45.81110  ? 209 GLU A C    1 
ATOM   3162 O  O    . GLU A 1 229 ? 39.43844  -7.98838  -29.70117 1.000 44.26371  ? 209 GLU A O    1 
ATOM   3163 C  CB   . GLU A 1 229 ? 42.03388  -7.50613  -27.95540 1.000 45.37037  ? 209 GLU A CB   1 
ATOM   3164 C  CG   . GLU A 1 229 ? 42.75850  -6.23921  -28.24371 1.000 52.49581  ? 209 GLU A CG   1 
ATOM   3165 C  CD   . GLU A 1 229 ? 44.18122  -6.49502  -28.68018 1.000 62.39167  ? 209 GLU A CD   1 
ATOM   3166 O  OE1  . GLU A 1 229 ? 44.92860  -7.14062  -27.90575 1.000 63.94671  ? 209 GLU A OE1  1 
ATOM   3167 O  OE2  . GLU A 1 229 ? 44.53724  -6.05344  -29.79132 1.000 70.66668  ? 209 GLU A OE2  1 
ATOM   3168 H  H    . GLU A 1 229 ? 39.70099  -9.06617  -27.54648 1.000 44.12450  ? 209 GLU A H    1 
ATOM   3169 H  HA   . GLU A 1 229 ? 40.44956  -6.50007  -27.13196 1.000 47.34542  ? 209 GLU A HA   1 
ATOM   3170 H  HB2  . GLU A 1 229 ? 42.43908  -7.91182  -27.17302 1.000 54.46820  ? 209 GLU A HB2  1 
ATOM   3171 H  HB3  . GLU A 1 229 ? 42.13559  -8.09088  -28.72261 1.000 54.46820  ? 209 GLU A HB3  1 
ATOM   3172 H  HG2  . GLU A 1 229 ? 42.30237  -5.76480  -28.95629 1.000 63.01873  ? 209 GLU A HG2  1 
ATOM   3173 H  HG3  . GLU A 1 229 ? 42.77972  -5.69326  -27.44222 1.000 63.01873  ? 209 GLU A HG3  1 
ATOM   3174 N  N    . VAL A 1 230 ? 39.52504  -5.77489  -29.27516 1.000 43.50183  ? 210 VAL A N    1 
ATOM   3175 C  CA   . VAL A 1 230 ? 38.77497  -5.35515  -30.45726 1.000 41.79572  ? 210 VAL A CA   1 
ATOM   3176 C  C    . VAL A 1 230 ? 39.44346  -4.06919  -30.94860 1.000 56.10863  ? 210 VAL A C    1 
ATOM   3177 O  O    . VAL A 1 230 ? 39.30709  -3.01347  -30.31913 1.000 53.85347  ? 210 VAL A O    1 
ATOM   3178 C  CB   . VAL A 1 230 ? 37.28667  -5.11885  -30.17975 1.000 46.97876  ? 210 VAL A CB   1 
ATOM   3179 C  CG1  . VAL A 1 230 ? 36.58712  -4.61063  -31.43318 1.000 54.84111  ? 210 VAL A CG1  1 
ATOM   3180 C  CG2  . VAL A 1 230 ? 36.59546  -6.39977  -29.68970 1.000 44.68813  ? 210 VAL A CG2  1 
ATOM   3181 H  H    . VAL A 1 230 ? 39.77509  -5.11534  -28.78316 1.000 52.22595  ? 210 VAL A H    1 
ATOM   3182 H  HA   . VAL A 1 230 ? 38.83767  -6.03704  -31.14427 1.000 50.17863  ? 210 VAL A HA   1 
ATOM   3183 H  HB   . VAL A 1 230 ? 37.21688  -4.45064  -29.48009 1.000 56.39828  ? 210 VAL A HB   1 
ATOM   3184 H  HG11 . VAL A 1 230 ? 35.62792  -4.69382  -31.31523 1.000 65.83310  ? 210 VAL A HG11 1 
ATOM   3185 H  HG12 . VAL A 1 230 ? 36.82389  -3.68022  -31.57172 1.000 65.83310  ? 210 VAL A HG12 1 
ATOM   3186 H  HG13 . VAL A 1 230 ? 36.87432  -5.14163  -32.19242 1.000 65.83310  ? 210 VAL A HG13 1 
ATOM   3187 H  HG21 . VAL A 1 230 ? 35.65350  -6.21614  -29.54865 1.000 53.64951  ? 210 VAL A HG21 1 
ATOM   3188 H  HG22 . VAL A 1 230 ? 36.70062  -7.09198  -30.36103 1.000 53.64951  ? 210 VAL A HG22 1 
ATOM   3189 H  HG23 . VAL A 1 230 ? 37.00587  -6.68135  -28.85713 1.000 53.64951  ? 210 VAL A HG23 1 
ATOM   3190 N  N    . ASP A 1 231 ? 40.17177  -4.15430  -32.05639 1.000 56.42583  ? 211 ASP A N    1 
ATOM   3191 C  CA   . ASP A 1 231 ? 40.75522  -2.96822  -32.69040 1.000 58.73986  ? 211 ASP A CA   1 
ATOM   3192 C  C    . ASP A 1 231 ? 41.71872  -2.26717  -31.73627 1.000 60.68780  ? 211 ASP A C    1 
ATOM   3193 O  O    . ASP A 1 231 ? 41.66900  -1.05122  -31.54256 1.000 67.94050  ? 211 ASP A O    1 
ATOM   3194 C  CB   . ASP A 1 231 ? 39.65090  -2.01287  -33.14692 1.000 70.09625  ? 211 ASP A CB   1 
ATOM   3195 C  CG   . ASP A 1 231 ? 38.67695  -2.65943  -34.12388 1.000 76.34703  ? 211 ASP A CG   1 
ATOM   3196 O  OD1  . ASP A 1 231 ? 39.09610  -3.56310  -34.87936 1.000 81.46367  ? 211 ASP A OD1  1 
ATOM   3197 O  OD2  . ASP A 1 231 ? 37.47970  -2.28761  -34.10803 1.000 66.05895  ? 211 ASP A OD2  1 
ATOM   3198 H  H    . ASP A 1 231 ? 40.34543  -4.89071  -32.46522 1.000 67.73476  ? 211 ASP A H    1 
ATOM   3199 H  HA   . ASP A 1 231 ? 41.26251  -3.24381  -33.46989 1.000 70.51159  ? 211 ASP A HA   1 
ATOM   3200 H  HB2  . ASP A 1 231 ? 39.14712  -1.71900  -32.37184 1.000 84.13927  ? 211 ASP A HB2  1 
ATOM   3201 H  HB3  . ASP A 1 231 ? 40.05582  -1.24986  -33.58822 1.000 84.13927  ? 211 ASP A HB3  1 
ATOM   3202 N  N    . GLY A 1 232 ? 42.59576  -3.05418  -31.12477 1.000 52.18196  ? 212 GLY A N    1 
ATOM   3203 C  CA   . GLY A 1 232 ? 43.56322  -2.52948  -30.18352 1.000 59.60798  ? 212 GLY A CA   1 
ATOM   3204 C  C    . GLY A 1 232 ? 42.98338  -2.02502  -28.88576 1.000 53.33953  ? 212 GLY A C    1 
ATOM   3205 O  O    . GLY A 1 232 ? 43.70162  -1.39158  -28.10391 1.000 54.99801  ? 212 GLY A O    1 
ATOM   3206 H  H    . GLY A 1 232 ? 42.64860  -3.90456  -31.24169 1.000 62.64211  ? 212 GLY A H    1 
ATOM   3207 H  HA2  . GLY A 1 232 ? 44.19904  -3.23019  -29.96988 1.000 71.55334  ? 212 GLY A HA2  1 
ATOM   3208 H  HA3  . GLY A 1 232 ? 44.03452  -1.79233  -30.60230 1.000 71.55334  ? 212 GLY A HA3  1 
ATOM   3209 N  N    . GLU A 1 233 ? 41.70948  -2.28971  -28.62485 1.000 46.14128  ? 213 GLU A N    1 
ATOM   3210 C  CA   . GLU A 1 233 ? 41.03208  -1.80496  -27.43770 1.000 48.45734  ? 213 GLU A CA   1 
ATOM   3211 C  C    . GLU A 1 233 ? 40.72970  -2.99333  -26.53691 1.000 45.02035  ? 213 GLU A C    1 
ATOM   3212 O  O    . GLU A 1 233 ? 40.37012  -4.07546  -27.02239 1.000 39.24841  ? 213 GLU A O    1 
ATOM   3213 C  CB   . GLU A 1 233 ? 39.71786  -1.09106  -27.79221 1.000 47.20799  ? 213 GLU A CB   1 
ATOM   3214 C  CG   . GLU A 1 233 ? 39.89974  0.14599   -28.66466 1.000 52.65930  ? 213 GLU A CG   1 
ATOM   3215 C  CD   . GLU A 1 233 ? 40.53960  1.27748   -27.90109 1.000 67.45468  ? 213 GLU A CD   1 
ATOM   3216 O  OE1  . GLU A 1 233 ? 40.80152  1.08414   -26.69828 1.000 69.43243  ? 213 GLU A OE1  1 
ATOM   3217 O  OE2  . GLU A 1 233 ? 40.83533  2.33316   -28.50766 1.000 73.04537  ? 213 GLU A OE2  1 
ATOM   3218 H  H    . GLU A 1 233 ? 41.20541  -2.76180  -29.13734 1.000 55.39329  ? 213 GLU A H    1 
ATOM   3219 H  HA   . GLU A 1 233 ? 41.59869  -1.17199  -26.96951 1.000 58.17257  ? 213 GLU A HA   1 
ATOM   3220 H  HB2  . GLU A 1 233 ? 39.14772  -1.71061  -28.27387 1.000 56.67335  ? 213 GLU A HB2  1 
ATOM   3221 H  HB3  . GLU A 1 233 ? 39.28452  -0.81159  -26.97062 1.000 56.67335  ? 213 GLU A HB3  1 
ATOM   3222 H  HG2  . GLU A 1 233 ? 40.47041  -0.07427  -29.41747 1.000 63.21492  ? 213 GLU A HG2  1 
ATOM   3223 H  HG3  . GLU A 1 233 ? 39.03294  0.44448   -28.98160 1.000 63.21492  ? 213 GLU A HG3  1 
ATOM   3224 N  N    . ARG A 1 234 ? 40.84835  -2.77698  -25.22585 1.000 35.46168  ? 214 ARG A N    1 
ATOM   3225 C  CA   . ARG A 1 234 ? 40.50081  -3.77965  -24.21730 1.000 37.26073  ? 214 ARG A CA   1 
ATOM   3226 C  C    . ARG A 1 234 ? 39.61392  -3.14978  -23.15578 1.000 38.27275  ? 214 ARG A C    1 
ATOM   3227 O  O    . ARG A 1 234 ? 39.43037  -1.93313  -23.11308 1.000 40.63876  ? 214 ARG A O    1 
ATOM   3228 C  CB   . ARG A 1 234 ? 41.76657  -4.37586  -23.57199 1.000 37.27986  ? 214 ARG A CB   1 
ATOM   3229 C  CG   . ARG A 1 234 ? 42.67948  -5.09612  -24.55587 1.000 42.22471  ? 214 ARG A CG   1 
ATOM   3230 C  CD   . ARG A 1 234 ? 43.47212  -6.22478  -23.89963 1.000 51.48488  ? 214 ARG A CD   1 
ATOM   3231 N  NE   . ARG A 1 234 ? 44.20429  -6.98713  -24.90388 1.000 55.84203  ? 214 ARG A NE   1 
ATOM   3232 C  CZ   . ARG A 1 234 ? 44.81120  -8.14582  -24.68936 1.000 56.58225  ? 214 ARG A CZ   1 
ATOM   3233 N  NH1  . ARG A 1 234 ? 44.80506  -8.72370  -23.49602 1.000 52.64436  ? 214 ARG A NH1  1 
ATOM   3234 N  NH2  . ARG A 1 234 ? 45.44130  -8.74039  -25.69922 1.000 63.05163  ? 214 ARG A NH2  1 
ATOM   3235 H  H    . ARG A 1 234 ? 41.13475  -2.03964  -24.88836 1.000 42.57778  ? 214 ARG A H    1 
ATOM   3236 H  HA   . ARG A 1 234 ? 40.00060  -4.49706  -24.63682 1.000 44.73663  ? 214 ARG A HA   1 
ATOM   3237 H  HB2  . ARG A 1 234 ? 42.27706  -3.65766  -23.16642 1.000 44.75960  ? 214 ARG A HB2  1 
ATOM   3238 H  HB3  . ARG A 1 234 ? 41.49852  -5.01607  -22.89437 1.000 44.75960  ? 214 ARG A HB3  1 
ATOM   3239 H  HG2  . ARG A 1 234 ? 42.14124  -5.48007  -25.26564 1.000 50.69341  ? 214 ARG A HG2  1 
ATOM   3240 H  HG3  . ARG A 1 234 ? 43.31185  -4.46044  -24.92590 1.000 50.69341  ? 214 ARG A HG3  1 
ATOM   3241 H  HD2  . ARG A 1 234 ? 44.10880  -5.85119  -23.27037 1.000 61.80562  ? 214 ARG A HD2  1 
ATOM   3242 H  HD3  . ARG A 1 234 ? 42.86368  -6.82403  -23.43964 1.000 61.80562  ? 214 ARG A HD3  1 
ATOM   3243 H  HE   . ARG A 1 234 ? 44.24564  -6.65924  -25.69784 1.000 67.03420  ? 214 ARG A HE   1 
ATOM   3244 H  HH11 . ARG A 1 234 ? 44.40041  -8.34639  -22.83762 1.000 63.19699  ? 214 ARG A HH11 1 
ATOM   3245 H  HH12 . ARG A 1 234 ? 45.20574  -9.47583  -23.38041 1.000 63.19699  ? 214 ARG A HH12 1 
ATOM   3246 H  HH21 . ARG A 1 234 ? 45.45048  -8.37262  -26.47657 1.000 75.68572  ? 214 ARG A HH21 1 
ATOM   3247 H  HH22 . ARG A 1 234 ? 45.83938  -9.49245  -25.57460 1.000 75.68572  ? 214 ARG A HH22 1 
ATOM   3248 N  N    . LEU A 1 235 ? 38.98947  -3.99691  -22.34270 1.000 34.88721  ? 215 LEU A N    1 
ATOM   3249 C  CA   . LEU A 1 235 ? 38.18873  -3.50364  -21.23592 1.000 29.48737  ? 215 LEU A CA   1 
ATOM   3250 C  C    . LEU A 1 235 ? 39.09440  -3.04743  -20.09577 1.000 33.57357  ? 215 LEU A C    1 
ATOM   3251 O  O    . LEU A 1 235 ? 40.02148  -3.75883  -19.70956 1.000 35.78869  ? 215 LEU A O    1 
ATOM   3252 C  CB   . LEU A 1 235 ? 37.24864  -4.59242  -20.73758 1.000 30.71929  ? 215 LEU A CB   1 
ATOM   3253 C  CG   . LEU A 1 235 ? 36.20583  -5.02605  -21.74068 1.000 30.13269  ? 215 LEU A CG   1 
ATOM   3254 C  CD1  . LEU A 1 235 ? 35.53915  -6.35574  -21.31348 1.000 30.97891  ? 215 LEU A CD1  1 
ATOM   3255 C  CD2  . LEU A 1 235 ? 35.13592  -3.93273  -21.94631 1.000 31.91791  ? 215 LEU A CD2  1 
ATOM   3256 H  H    . LEU A 1 235 ? 39.01562  -4.85364  -22.41297 1.000 41.88842  ? 215 LEU A H    1 
ATOM   3257 H  HA   . LEU A 1 235 ? 37.65998  -2.74800  -21.53649 1.000 35.26603  ? 215 LEU A HA   1 
ATOM   3258 H  HB2  . LEU A 1 235 ? 37.77598  -5.37293  -20.50605 1.000 36.88691  ? 215 LEU A HB2  1 
ATOM   3259 H  HB3  . LEU A 1 235 ? 36.78265  -4.26235  -19.95349 1.000 36.88691  ? 215 LEU A HB3  1 
ATOM   3260 H  HG   . LEU A 1 235 ? 36.65116  -5.17131  -22.59008 1.000 36.18299  ? 215 LEU A HG   1 
ATOM   3261 H  HD11 . LEU A 1 235 ? 34.85368  -6.58719  -21.95959 1.000 37.19846  ? 215 LEU A HD11 1 
ATOM   3262 H  HD12 . LEU A 1 235 ? 36.21391  -7.05193  -21.28336 1.000 37.19846  ? 215 LEU A HD12 1 
ATOM   3263 H  HD13 . LEU A 1 235 ? 35.14172  -6.24210  -20.43596 1.000 37.19846  ? 215 LEU A HD13 1 
ATOM   3264 H  HD21 . LEU A 1 235 ? 34.44177  -4.27605  -22.53042 1.000 38.32526  ? 215 LEU A HD21 1 
ATOM   3265 H  HD22 . LEU A 1 235 ? 34.75671  -3.69608  -21.08544 1.000 38.32526  ? 215 LEU A HD22 1 
ATOM   3266 H  HD23 . LEU A 1 235 ? 35.55256  -3.15497  -22.34929 1.000 38.32526  ? 215 LEU A HD23 1 
ATOM   3267 N  N    . SER A 1 236 ? 38.80056  -1.87789  -19.54035 1.000 36.26562  ? 216 SER A N    1 
ATOM   3268 C  CA   . SER A 1 236 ? 39.46839  -1.42844  -18.32688 1.000 35.81658  ? 216 SER A CA   1 
ATOM   3269 C  C    . SER A 1 236 ? 38.89902  -2.14445  -17.10389 1.000 36.31056  ? 216 SER A C    1 
ATOM   3270 O  O    . SER A 1 236 ? 37.86792  -2.78082  -17.16620 1.000 33.11789  ? 216 SER A O    1 
ATOM   3271 C  CB   . SER A 1 236 ? 39.28886  0.07103   -18.14604 1.000 35.00959  ? 216 SER A CB   1 
ATOM   3272 O  OG   . SER A 1 236 ? 37.92988  0.31196   -17.84455 1.000 36.34788  ? 216 SER A OG   1 
ATOM   3273 H  H    . SER A 1 236 ? 38.21723  -1.32564  -19.84751 1.000 43.54251  ? 216 SER A H    1 
ATOM   3274 H  HA   . SER A 1 236 ? 40.41412  -1.63026  -18.40273 1.000 43.00366  ? 216 SER A HA   1 
ATOM   3275 H  HB2  . SER A 1 236 ? 39.84644  0.38189   -17.41571 1.000 42.03526  ? 216 SER A HB2  1 
ATOM   3276 H  HB3  . SER A 1 236 ? 39.52898  0.53082   -18.96570 1.000 42.03526  ? 216 SER A HB3  1 
ATOM   3277 H  HG   . SER A 1 236 ? 37.79783  1.13638   -17.75239 1.000 43.64122  ? 216 SER A HG   1 
ATOM   3278 N  N    . ASP A 1 237 ? 39.58700  -2.01283  -15.95821 1.000 39.23856  ? 217 ASP A N    1 
ATOM   3279 C  CA   . ASP A 1 237 ? 39.08568  -2.65471  -14.74003 1.000 34.69710  ? 217 ASP A CA   1 
ATOM   3280 C  C    . ASP A 1 237 ? 37.73419  -2.08224  -14.32054 1.000 34.63551  ? 217 ASP A C    1 
ATOM   3281 O  O    . ASP A 1 237 ? 36.83470  -2.82264  -13.87444 1.000 34.01205  ? 217 ASP A O    1 
ATOM   3282 C  CB   . ASP A 1 237 ? 40.10777  -2.45253  -13.61553 1.000 38.83694  ? 217 ASP A CB   1 
ATOM   3283 C  CG   . ASP A 1 237 ? 41.33492  -3.36451  -13.71366 1.000 46.42634  ? 217 ASP A CG   1 
ATOM   3284 O  OD1  . ASP A 1 237 ? 41.45558  -4.14534  -14.66990 1.000 43.89241  ? 217 ASP A OD1  1 
ATOM   3285 O  OD2  . ASP A 1 237 ? 42.23644  -3.23619  -12.84775 1.000 45.88827  ? 217 ASP A OD2  1 
ATOM   3286 H  H    . ASP A 1 237 ? 40.31997  -1.57261  -15.86564 1.000 47.11004  ? 217 ASP A H    1 
ATOM   3287 H  HA   . ASP A 1 237 ? 38.97007  -3.60351  -14.90534 1.000 41.66028  ? 217 ASP A HA   1 
ATOM   3288 H  HB2  . ASP A 1 237 ? 40.42058  -1.53471  -13.64108 1.000 46.62809  ? 217 ASP A HB2  1 
ATOM   3289 H  HB3  . ASP A 1 237 ? 39.67505  -2.63203  -12.76616 1.000 46.62809  ? 217 ASP A HB3  1 
ATOM   3290 N  N    . ASP A 1 238 ? 37.56138  -0.75853  -14.44490 1.000 37.97448  ? 218 ASP A N    1 
ATOM   3291 C  CA   . ASP A 1 238 ? 36.25810  -0.16241  -14.16450 1.000 36.94908  ? 218 ASP A CA   1 
ATOM   3292 C  C    . ASP A 1 238 ? 35.17574  -0.77721  -15.04675 1.000 31.68409  ? 218 ASP A C    1 
ATOM   3293 O  O    . ASP A 1 238 ? 34.07131  -1.09061  -14.58016 1.000 30.39576  ? 218 ASP A O    1 
ATOM   3294 C  CB   . ASP A 1 238 ? 36.28544  1.35418   -14.39998 1.000 39.13065  ? 218 ASP A CB   1 
ATOM   3295 C  CG   . ASP A 1 238 ? 37.11434  2.10513   -13.39183 1.000 48.01016  ? 218 ASP A CG   1 
ATOM   3296 O  OD1  . ASP A 1 238 ? 37.50728  1.52382   -12.35701 1.000 43.18779  ? 218 ASP A OD1  1 
ATOM   3297 O  OD2  . ASP A 1 238 ? 37.35986  3.30356   -13.65434 1.000 46.74872  ? 218 ASP A OD2  1 
ATOM   3298 H  H    . ASP A 1 238 ? 38.17031  -0.20050  -14.68448 1.000 45.59313  ? 218 ASP A H    1 
ATOM   3299 H  HA   . ASP A 1 238 ? 36.05253  -0.32636  -13.23082 1.000 44.36266  ? 218 ASP A HA   1 
ATOM   3300 H  HB2  . ASP A 1 238 ? 36.65809  1.52783   -15.27855 1.000 46.98055  ? 218 ASP A HB2  1 
ATOM   3301 H  HB3  . ASP A 1 238 ? 35.37858  1.69491   -14.35100 1.000 46.98055  ? 218 ASP A HB3  1 
ATOM   3302 N  N    . GLU A 1 239 ? 35.47404  -0.93480  -16.34055 1.000 31.32077  ? 219 GLU A N    1 
ATOM   3303 C  CA   . GLU A 1 239 ? 34.49297  -1.48823  -17.26530 1.000 29.71465  ? 219 GLU A CA   1 
ATOM   3304 C  C    . GLU A 1 239 ? 34.21860  -2.95271  -16.97155 1.000 27.34138  ? 219 GLU A C    1 
ATOM   3305 O  O    . GLU A 1 239 ? 33.07922  -3.40711  -17.07846 1.000 28.25800  ? 219 GLU A O    1 
ATOM   3306 C  CB   . GLU A 1 239 ? 34.98158  -1.30171  -18.70648 1.000 32.44757  ? 219 GLU A CB   1 
ATOM   3307 C  CG   . GLU A 1 239 ? 34.93472  0.14573   -19.14568 1.000 33.72253  ? 219 GLU A CG   1 
ATOM   3308 C  CD   . GLU A 1 239 ? 35.76169  0.44648   -20.38506 1.000 39.15232  ? 219 GLU A CD   1 
ATOM   3309 O  OE1  . GLU A 1 239 ? 36.57199  -0.40924  -20.85599 1.000 39.13978  ? 219 GLU A OE1  1 
ATOM   3310 O  OE2  . GLU A 1 239 ? 35.58447  1.57206   -20.89559 1.000 48.09823  ? 219 GLU A OE2  1 
ATOM   3311 H  H    . GLU A 1 239 ? 36.22824  -0.73080  -16.69994 1.000 37.60869  ? 219 GLU A H    1 
ATOM   3312 H  HA   . GLU A 1 239 ? 33.65618  -1.00802  -17.16493 1.000 35.68135  ? 219 GLU A HA   1 
ATOM   3313 H  HB2  . GLU A 1 239 ? 35.89951  -1.60819  -18.77265 1.000 38.96084  ? 219 GLU A HB2  1 
ATOM   3314 H  HB3  . GLU A 1 239 ? 34.41597  -1.81704  -19.30265 1.000 38.96084  ? 219 GLU A HB3  1 
ATOM   3315 H  HG2  . GLU A 1 239 ? 34.01446  0.38126   -19.34197 1.000 40.49080  ? 219 GLU A HG2  1 
ATOM   3316 H  HG3  . GLU A 1 239 ? 35.27262  0.70021   -18.42507 1.000 40.49080  ? 219 GLU A HG3  1 
ATOM   3317 N  N    . LEU A 1 240 ? 35.26191  -3.71086  -16.61823 1.000 27.86589  ? 220 LEU A N    1 
ATOM   3318 C  CA   . LEU A 1 240 ? 35.07490  -5.11830  -16.28364 1.000 28.16496  ? 220 LEU A CA   1 
ATOM   3319 C  C    . LEU A 1 240 ? 34.13468  -5.25542  -15.09188 1.000 27.92396  ? 220 LEU A C    1 
ATOM   3320 O  O    . LEU A 1 240 ? 33.24858  -6.11884  -15.08175 1.000 26.03778  ? 220 LEU A O    1 
ATOM   3321 C  CB   . LEU A 1 240 ? 36.41568  -5.79097  -15.98928 1.000 30.10882  ? 220 LEU A CB   1 
ATOM   3322 C  CG   . LEU A 1 240 ? 37.33538  -6.11943  -17.16564 1.000 36.94328  ? 220 LEU A CG   1 
ATOM   3323 C  CD1  . LEU A 1 240 ? 38.77241  -6.34941  -16.75283 1.000 42.76693  ? 220 LEU A CD1  1 
ATOM   3324 C  CD2  . LEU A 1 240 ? 36.68780  -7.31352  -17.93206 1.000 34.63171  ? 220 LEU A CD2  1 
ATOM   3325 H  H    . LEU A 1 240 ? 36.07509  -3.43584  -16.56611 1.000 33.46283  ? 220 LEU A H    1 
ATOM   3326 H  HA   . LEU A 1 240 ? 34.68753  -5.57474  -17.04686 1.000 33.82171  ? 220 LEU A HA   1 
ATOM   3327 H  HB2  . LEU A 1 240 ? 36.91605  -5.20319  -15.40187 1.000 36.15434  ? 220 LEU A HB2  1 
ATOM   3328 H  HB3  . LEU A 1 240 ? 36.23036  -6.63017  -15.53952 1.000 36.15434  ? 220 LEU A HB3  1 
ATOM   3329 H  HG   . LEU A 1 240 ? 37.41403  -5.36356  -17.76846 1.000 44.35569  ? 220 LEU A HG   1 
ATOM   3330 H  HD11 . LEU A 1 240 ? 39.29304  -6.58202  -17.53752 1.000 51.34408  ? 220 LEU A HD11 1 
ATOM   3331 H  HD12 . LEU A 1 240 ? 39.12038  -5.53653  -16.35403 1.000 51.34408  ? 220 LEU A HD12 1 
ATOM   3332 H  HD13 . LEU A 1 240 ? 38.80381  -7.07372  -16.10840 1.000 51.34408  ? 220 LEU A HD13 1 
ATOM   3333 H  HD21 . LEU A 1 240 ? 37.26579  -7.56660  -18.66879 1.000 41.58182  ? 220 LEU A HD21 1 
ATOM   3334 H  HD22 . LEU A 1 240 ? 36.58290  -8.06053  -17.32224 1.000 41.58182  ? 220 LEU A HD22 1 
ATOM   3335 H  HD23 . LEU A 1 240 ? 35.82135  -7.03877  -18.27069 1.000 41.58182  ? 220 LEU A HD23 1 
ATOM   3336 N  N    . VAL A 1 241 ? 34.29087  -4.39134  -14.07766 1.000 30.07561  ? 221 VAL A N    1 
ATOM   3337 C  CA   . VAL A 1 241 ? 33.36878  -4.46364  -12.93532 1.000 28.23875  ? 221 VAL A CA   1 
ATOM   3338 C  C    . VAL A 1 241 ? 31.92921  -4.21205  -13.36755 1.000 29.57003  ? 221 VAL A C    1 
ATOM   3339 O  O    . VAL A 1 241 ? 31.02073  -4.96556  -13.00534 1.000 24.77805  ? 221 VAL A O    1 
ATOM   3340 C  CB   . VAL A 1 241 ? 33.80699  -3.49245  -11.82251 1.000 29.47969  ? 221 VAL A CB   1 
ATOM   3341 C  CG1  . VAL A 1 241 ? 32.73470  -3.46155  -10.69885 1.000 30.29264  ? 221 VAL A CG1  1 
ATOM   3342 C  CG2  . VAL A 1 241 ? 35.14929  -3.92476  -11.28252 1.000 31.56222  ? 221 VAL A CG2  1 
ATOM   3343 H  H    . VAL A 1 241 ? 34.89530  -3.78151  -14.02904 1.000 36.11449  ? 221 VAL A H    1 
ATOM   3344 H  HA   . VAL A 1 241 ? 33.40785  -5.36570  -12.58084 1.000 33.91026  ? 221 VAL A HA   1 
ATOM   3345 H  HB   . VAL A 1 241 ? 33.89451  -2.59319  -12.17546 1.000 35.39939  ? 221 VAL A HB   1 
ATOM   3346 H  HG11 . VAL A 1 241 ? 33.13309  -3.09927  -9.89204  1.000 36.37493  ? 221 VAL A HG11 1 
ATOM   3347 H  HG12 . VAL A 1 241 ? 31.99551  -2.90143  -10.98305 1.000 36.37493  ? 221 VAL A HG12 1 
ATOM   3348 H  HG13 . VAL A 1 241 ? 32.42158  -4.36510  -10.53621 1.000 36.37493  ? 221 VAL A HG13 1 
ATOM   3349 H  HG21 . VAL A 1 241 ? 35.45106  -3.27458  -10.62899 1.000 37.89843  ? 221 VAL A HG21 1 
ATOM   3350 H  HG22 . VAL A 1 241 ? 35.05610  -4.79512  -10.86455 1.000 37.89843  ? 221 VAL A HG22 1 
ATOM   3351 H  HG23 . VAL A 1 241 ? 35.78287  -3.97582  -12.01523 1.000 37.89843  ? 221 VAL A HG23 1 
ATOM   3352 N  N    . MET A 1 242 ? 31.69362  -3.14843  -14.15136 1.000 27.84989  ? 222 MET A N    1 
ATOM   3353 C  CA   . MET A 1 242 ? 30.34081  -2.77220  -14.50954 1.000 27.38774  ? 222 MET A CA   1 
ATOM   3354 C  C    . MET A 1 242 ? 29.72080  -3.80642  -15.44072 1.000 24.77571  ? 222 MET A C    1 
ATOM   3355 O  O    . MET A 1 242 ? 28.56321  -4.16355  -15.27188 1.000 25.49194  ? 222 MET A O    1 
ATOM   3356 C  CB   . MET A 1 242 ? 30.35323  -1.39855  -15.16301 1.000 30.80007  ? 222 MET A CB   1 
ATOM   3357 C  CG   . MET A 1 242 ? 30.47848  -0.27266  -14.13824 1.000 37.94515  ? 222 MET A CG   1 
ATOM   3358 S  SD   . MET A 1 242 ? 28.89491  -0.05535  -13.25846 1.000 48.76322  ? 222 MET A SD   1 
ATOM   3359 C  CE   . MET A 1 242 ? 29.39495  1.08176   -11.97866 1.000 49.81945  ? 222 MET A CE   1 
ATOM   3360 H  H    . MET A 1 242 ? 32.30224  -2.63824  -14.48134 1.000 33.44364  ? 222 MET A H    1 
ATOM   3361 H  HA   . MET A 1 242 ? 29.80107  -2.71520  -13.70559 1.000 32.88905  ? 222 MET A HA   1 
ATOM   3362 H  HB2  . MET A 1 242 ? 31.10856  -1.34175  -15.76894 1.000 36.98384  ? 222 MET A HB2  1 
ATOM   3363 H  HB3  . MET A 1 242 ? 29.52524  -1.27189  -15.65219 1.000 36.98384  ? 222 MET A HB3  1 
ATOM   3364 H  HG2  . MET A 1 242 ? 31.16684  -0.49401  -13.49167 1.000 45.55794  ? 222 MET A HG2  1 
ATOM   3365 H  HG3  . MET A 1 242 ? 30.70127  0.55674   -14.58920 1.000 45.55794  ? 222 MET A HG3  1 
ATOM   3366 H  HE1  . MET A 1 242 ? 28.62876  1.28466   -11.41948 1.000 59.80710  ? 222 MET A HE1  1 
ATOM   3367 H  HE2  . MET A 1 242 ? 30.09352  0.67041   -11.44603 1.000 59.80710  ? 222 MET A HE2  1 
ATOM   3368 H  HE3  . MET A 1 242 ? 29.72819  1.89423   -12.39066 1.000 59.80710  ? 222 MET A HE3  1 
ATOM   3369 N  N    . GLU A 1 243 ? 30.47418  -4.30343  -16.42114 1.000 24.48455  ? 223 GLU A N    1 
ATOM   3370 C  CA   . GLU A 1 243 ? 29.88105  -5.24102  -17.36139 1.000 24.62460  ? 223 GLU A CA   1 
ATOM   3371 C  C    . GLU A 1 243 ? 29.63228  -6.59435  -16.70459 1.000 24.60397  ? 223 GLU A C    1 
ATOM   3372 O  O    . GLU A 1 243 ? 28.62558  -7.24282  -16.99870 1.000 24.32356  ? 223 GLU A O    1 
ATOM   3373 C  CB   . GLU A 1 243 ? 30.74968  -5.39081  -18.61002 1.000 27.27564  ? 223 GLU A CB   1 
ATOM   3374 C  CG   . GLU A 1 243 ? 30.89794  -4.13048  -19.43212 1.000 26.96551  ? 223 GLU A CG   1 
ATOM   3375 C  CD   . GLU A 1 243 ? 29.56402  -3.56547  -19.94543 1.000 28.00286  ? 223 GLU A CD   1 
ATOM   3376 O  OE1  . GLU A 1 243 ? 28.57954  -4.32119  -20.03524 1.000 29.33893  ? 223 GLU A OE1  1 
ATOM   3377 O  OE2  . GLU A 1 243 ? 29.52239  -2.33387  -20.21152 1.000 29.64401  ? 223 GLU A OE2  1 
ATOM   3378 H  H    . GLU A 1 243 ? 31.30300  -4.11838  -16.55685 1.000 29.40523  ? 223 GLU A H    1 
ATOM   3379 H  HA   . GLU A 1 243 ? 29.02745  -4.88302  -17.65137 1.000 29.57328  ? 223 GLU A HA   1 
ATOM   3380 H  HB2  . GLU A 1 243 ? 31.63824  -5.66683  -18.33583 1.000 32.75453  ? 223 GLU A HB2  1 
ATOM   3381 H  HB3  . GLU A 1 243 ? 30.35369  -6.06728  -19.18141 1.000 32.75453  ? 223 GLU A HB3  1 
ATOM   3382 H  HG2  . GLU A 1 243 ? 31.31697  -3.44810  -18.88469 1.000 32.38237  ? 223 GLU A HG2  1 
ATOM   3383 H  HG3  . GLU A 1 243 ? 31.45329  -4.32434  -20.20342 1.000 32.38237  ? 223 GLU A HG3  1 
ATOM   3384 N  N    . THR A 1 244 ? 30.52746  -7.03754  -15.79859 1.000 23.41935  ? 224 THR A N    1 
ATOM   3385 C  CA   . THR A 1 244 ? 30.24719  -8.30608  -15.14805 1.000 22.47543  ? 224 THR A CA   1 
ATOM   3386 C  C    . THR A 1 244 ? 29.08509  -8.16659  -14.17007 1.000 24.71228  ? 224 THR A C    1 
ATOM   3387 O  O    . THR A 1 244 ? 28.36505  -9.13474  -13.93392 1.000 23.67721  ? 224 THR A O    1 
ATOM   3388 C  CB   . THR A 1 244 ? 31.44912  -8.91112  -14.40444 1.000 25.74072  ? 224 THR A CB   1 
ATOM   3389 O  OG1  . THR A 1 244 ? 31.99259  -8.02928  -13.41081 1.000 27.34614  ? 224 THR A OG1  1 
ATOM   3390 C  CG2  . THR A 1 244 ? 32.56054  -9.31342  -15.36315 1.000 27.70490  ? 224 THR A CG2  1 
ATOM   3391 H  H    . THR A 1 244 ? 31.25374  -6.63995  -15.56615 1.000 28.12698  ? 224 THR A H    1 
ATOM   3392 H  HA   . THR A 1 244 ? 30.03407  -8.92986  -15.85966 1.000 26.99428  ? 224 THR A HA   1 
ATOM   3393 H  HB   . THR A 1 244 ? 31.11691  -9.70272  -13.95290 1.000 30.91263  ? 224 THR A HB   1 
ATOM   3394 H  HG1  . THR A 1 244 ? 32.26238  -7.32064  -13.77226 1.000 32.83913  ? 224 THR A HG1  1 
ATOM   3395 H  HG21 . THR A 1 244 ? 33.29430  -9.71391  -14.87111 1.000 33.26964  ? 224 THR A HG21 1 
ATOM   3396 H  HG22 . THR A 1 244 ? 32.22595  -9.95620  -16.00796 1.000 33.26964  ? 224 THR A HG22 1 
ATOM   3397 H  HG23 . THR A 1 244 ? 32.88820  -8.53324  -15.83734 1.000 33.26964  ? 224 THR A HG23 1 
ATOM   3398 N  N    . LEU A 1 245 ? 28.85586  -6.97296  -13.61530 1.000 24.00967  ? 225 LEU A N    1 
ATOM   3399 C  CA   . LEU A 1 245 ? 27.68263  -6.79145  -12.75776 1.000 23.88006  ? 225 LEU A CA   1 
ATOM   3400 C  C    . LEU A 1 245 ? 26.37794  -6.88204  -13.55619 1.000 22.82632  ? 225 LEU A C    1 
ATOM   3401 O  O    . LEU A 1 245 ? 25.39347  -7.49632  -13.09963 1.000 21.93740  ? 225 LEU A O    1 
ATOM   3402 C  CB   . LEU A 1 245 ? 27.77780  -5.44618  -12.03298 1.000 25.52018  ? 225 LEU A CB   1 
ATOM   3403 C  CG   . LEU A 1 245 ? 26.64559  -5.18242  -11.04060 1.000 25.10589  ? 225 LEU A CG   1 
ATOM   3404 C  CD1  . LEU A 1 245 ? 26.53274  -6.34291  -10.02103 1.000 26.96329  ? 225 LEU A CD1  1 
ATOM   3405 C  CD2  . LEU A 1 245 ? 26.94309  -3.85052  -10.31589 1.000 30.60793  ? 225 LEU A CD2  1 
ATOM   3406 H  H    . LEU A 1 245 ? 29.34779  -6.27477  -13.71598 1.000 28.83537  ? 225 LEU A H    1 
ATOM   3407 H  HA   . LEU A 1 245 ? 27.66936  -7.49824  -12.09355 1.000 28.67984  ? 225 LEU A HA   1 
ATOM   3408 H  HB2  . LEU A 1 245 ? 28.61292  -5.41938  -11.54028 1.000 30.64797  ? 225 LEU A HB2  1 
ATOM   3409 H  HB3  . LEU A 1 245 ? 27.76007  -4.73711  -12.69465 1.000 30.64797  ? 225 LEU A HB3  1 
ATOM   3410 H  HG   . LEU A 1 245 ? 25.79485  -5.12202  -11.50265 1.000 30.15082  ? 225 LEU A HG   1 
ATOM   3411 H  HD11 . LEU A 1 245 ? 25.88774  -6.10153  -9.33794  1.000 32.37971  ? 225 LEU A HD11 1 
ATOM   3412 H  HD12 . LEU A 1 245 ? 26.23988  -7.14311  -10.48451 1.000 32.37971  ? 225 LEU A HD12 1 
ATOM   3413 H  HD13 . LEU A 1 245 ? 27.40156  -6.49392  -9.61700  1.000 32.37971  ? 225 LEU A HD13 1 
ATOM   3414 H  HD21 . LEU A 1 245 ? 26.23464  -3.67327  -9.67748  1.000 36.75327  ? 225 LEU A HD21 1 
ATOM   3415 H  HD22 . LEU A 1 245 ? 27.79309  -3.92503  -9.85454  1.000 36.75327  ? 225 LEU A HD22 1 
ATOM   3416 H  HD23 . LEU A 1 245 ? 26.98395  -3.13664  -10.97133 1.000 36.75327  ? 225 LEU A HD23 1 
ATOM   3417 N  N    . LEU A 1 246 ? 26.34138  -6.25622  -14.74363 1.000 23.01942  ? 226 LEU A N    1 
ATOM   3418 C  CA   . LEU A 1 246 ? 25.20181  -6.38101  -15.64296 1.000 21.10766  ? 226 LEU A CA   1 
ATOM   3419 C  C    . LEU A 1 246 ? 24.93732  -7.84771  -15.94872 1.000 20.75375  ? 226 LEU A C    1 
ATOM   3420 O  O    . LEU A 1 246 ? 23.79969  -8.29029  -15.91397 1.000 21.21176  ? 226 LEU A O    1 
ATOM   3421 C  CB   . LEU A 1 246 ? 25.47826  -5.57538  -16.93349 1.000 21.10961  ? 226 LEU A CB   1 
ATOM   3422 C  CG   . LEU A 1 246 ? 24.38651  -5.62790  -17.99100 1.000 20.97763  ? 226 LEU A CG   1 
ATOM   3423 C  CD1  . LEU A 1 246 ? 23.06287  -5.10142  -17.49032 1.000 23.19916  ? 226 LEU A CD1  1 
ATOM   3424 C  CD2  . LEU A 1 246 ? 24.84671  -4.82717  -19.23110 1.000 23.38712  ? 226 LEU A CD2  1 
ATOM   3425 H  H    . LEU A 1 246 ? 26.96925  -5.75304  -15.04725 1.000 27.64707  ? 226 LEU A H    1 
ATOM   3426 H  HA   . LEU A 1 246 ? 24.40440  -6.01157  -15.23242 1.000 25.35295  ? 226 LEU A HA   1 
ATOM   3427 H  HB2  . LEU A 1 246 ? 25.59930  -4.64428  -16.68994 1.000 25.35529  ? 226 LEU A HB2  1 
ATOM   3428 H  HB3  . LEU A 1 246 ? 26.28919  -5.92039  -17.33878 1.000 25.35529  ? 226 LEU A HB3  1 
ATOM   3429 H  HG   . LEU A 1 246 ? 24.23604  -6.55592  -18.22983 1.000 25.19692  ? 226 LEU A HG   1 
ATOM   3430 H  HD11 . LEU A 1 246 ? 22.43368  -5.07592  -18.22813 1.000 27.86276  ? 226 LEU A HD11 1 
ATOM   3431 H  HD12 . LEU A 1 246 ? 22.73208  -5.68982  -16.79370 1.000 27.86276  ? 226 LEU A HD12 1 
ATOM   3432 H  HD13 . LEU A 1 246 ? 23.19232  -4.20819  -17.13497 1.000 27.86276  ? 226 LEU A HD13 1 
ATOM   3433 H  HD21 . LEU A 1 246 ? 24.14244  -4.84523  -19.89787 1.000 28.08830  ? 226 LEU A HD21 1 
ATOM   3434 H  HD22 . LEU A 1 246 ? 25.02825  -3.91180  -18.96643 1.000 28.08830  ? 226 LEU A HD22 1 
ATOM   3435 H  HD23 . LEU A 1 246 ? 25.65141  -5.23385  -19.58883 1.000 28.08830  ? 226 LEU A HD23 1 
ATOM   3436 N  N    . ILE A 1 247 ? 25.98767  -8.62120  -16.21069 1.000 22.20464  ? 227 ILE A N    1 
ATOM   3437 C  CA   . ILE A 1 247 ? 25.84440  -10.04364 -16.49457 1.000 21.34498  ? 227 ILE A CA   1 
ATOM   3438 C  C    . ILE A 1 247 ? 25.36188  -10.80866 -15.25351 1.000 21.25630  ? 227 ILE A C    1 
ATOM   3439 O  O    . ILE A 1 247 ? 24.56686  -11.73780 -15.36400 1.000 24.34703  ? 227 ILE A O    1 
ATOM   3440 C  CB   . ILE A 1 247 ? 27.20147  -10.56584 -16.99548 1.000 25.58751  ? 227 ILE A CB   1 
ATOM   3441 C  CG1  . ILE A 1 247 ? 27.46693  -10.09847 -18.43535 1.000 24.36005  ? 227 ILE A CG1  1 
ATOM   3442 C  CG2  . ILE A 1 247 ? 27.33868  -12.08405 -16.87608 1.000 23.39762  ? 227 ILE A CG2  1 
ATOM   3443 C  CD1  . ILE A 1 247 ? 28.95480  -10.11755 -18.78424 1.000 25.99738  ? 227 ILE A CD1  1 
ATOM   3444 H  H    . ILE A 1 247 ? 26.80162  -8.34425  -16.23038 1.000 26.66933  ? 227 ILE A H    1 
ATOM   3445 H  HA   . ILE A 1 247 ? 25.17083  -10.17497 -17.18011 1.000 25.63774  ? 227 ILE A HA   1 
ATOM   3446 H  HB   . ILE A 1 247 ? 27.87566  -10.18245 -16.41292 1.000 30.72878  ? 227 ILE A HB   1 
ATOM   3447 H  HG12 . ILE A 1 247 ? 27.00416  -10.68792 -19.05122 1.000 29.25582  ? 227 ILE A HG12 1 
ATOM   3448 H  HG13 . ILE A 1 247 ? 27.14342  -9.18993  -18.53930 1.000 29.25582  ? 227 ILE A HG13 1 
ATOM   3449 H  HG21 . ILE A 1 247 ? 27.98251  -12.39546 -17.53137 1.000 28.10091  ? 227 ILE A HG21 1 
ATOM   3450 H  HG22 . ILE A 1 247 ? 27.64380  -12.30421 -15.98203 1.000 28.10091  ? 227 ILE A HG22 1 
ATOM   3451 H  HG23 . ILE A 1 247 ? 26.47475  -12.49315 -17.04086 1.000 28.10091  ? 227 ILE A HG23 1 
ATOM   3452 H  HD11 . ILE A 1 247 ? 29.06698  -9.83313  -19.70479 1.000 31.22061  ? 227 ILE A HD11 1 
ATOM   3453 H  HD12 . ILE A 1 247 ? 29.42605  -9.51175  -18.19109 1.000 31.22061  ? 227 ILE A HD12 1 
ATOM   3454 H  HD13 . ILE A 1 247 ? 29.29368  -11.01961 -18.67310 1.000 31.22061  ? 227 ILE A HD13 1 
ATOM   3455 N  N    . LEU A 1 248 ? 25.88895  -10.49367 -14.07898 1.000 22.46435  ? 228 LEU A N    1 
ATOM   3456 C  CA   . LEU A 1 248 ? 25.48531  -11.20868 -12.86213 1.000 21.71352  ? 228 LEU A CA   1 
ATOM   3457 C  C    . LEU A 1 248 ? 23.99249  -11.05818 -12.64101 1.000 21.46504  ? 228 LEU A C    1 
ATOM   3458 O  O    . LEU A 1 248 ? 23.27909  -12.04153 -12.40143 1.000 20.25360  ? 228 LEU A O    1 
ATOM   3459 C  CB   . LEU A 1 248 ? 26.23753  -10.66868 -11.65669 1.000 23.12254  ? 228 LEU A CB   1 
ATOM   3460 C  CG   . LEU A 1 248 ? 25.71856  -11.12843 -10.28163 1.000 23.63336  ? 228 LEU A CG   1 
ATOM   3461 C  CD1  . LEU A 1 248 ? 26.03556  -12.56788 -10.11585 1.000 23.92027  ? 228 LEU A CD1  1 
ATOM   3462 C  CD2  . LEU A 1 248 ? 26.32592  -10.31061 -9.14590  1.000 25.09465  ? 228 LEU A CD2  1 
ATOM   3463 H  H    . LEU A 1 248 ? 26.47610  -9.87807  -13.95296 1.000 26.98098  ? 228 LEU A H    1 
ATOM   3464 H  HA   . LEU A 1 248 ? 25.70648  -12.14786 -12.96177 1.000 26.07999  ? 228 LEU A HA   1 
ATOM   3465 H  HB2  . LEU A 1 248 ? 27.16273  -10.95200 -11.72481 1.000 27.77081  ? 228 LEU A HB2  1 
ATOM   3466 H  HB3  . LEU A 1 248 ? 26.18488  -9.70029  -11.67536 1.000 27.77081  ? 228 LEU A HB3  1 
ATOM   3467 H  HG   . LEU A 1 248 ? 24.75895  -10.99457 -10.23547 1.000 28.38379  ? 228 LEU A HG   1 
ATOM   3468 H  HD11 . LEU A 1 248 ? 25.69652  -12.86920 -9.25844  1.000 28.72808  ? 228 LEU A HD11 1 
ATOM   3469 H  HD12 . LEU A 1 248 ? 25.61487  -13.06845 -10.83233 1.000 28.72808  ? 228 LEU A HD12 1 
ATOM   3470 H  HD13 . LEU A 1 248 ? 26.99777  -12.68542 -10.15089 1.000 28.72808  ? 228 LEU A HD13 1 
ATOM   3471 H  HD21 . LEU A 1 248 ? 25.94500  -10.60704 -8.30452  1.000 30.13734  ? 228 LEU A HD21 1 
ATOM   3472 H  HD22 . LEU A 1 248 ? 27.28666  -10.44412 -9.13933  1.000 30.13734  ? 228 LEU A HD22 1 
ATOM   3473 H  HD23 . LEU A 1 248 ? 26.12325  -9.37281  -9.28860  1.000 30.13734  ? 228 LEU A HD23 1 
ATOM   3474 N  N    . ILE A 1 249 ? 23.49347  -9.82802  -12.74654 1.000 20.76209  ? 229 ILE A N    1 
ATOM   3475 C  CA   . ILE A 1 249 ? 22.07360  -9.58417  -12.48981 1.000 20.55051  ? 229 ILE A CA   1 
ATOM   3476 C  C    . ILE A 1 249 ? 21.19061  -10.17248 -13.59799 1.000 21.63275  ? 229 ILE A C    1 
ATOM   3477 O  O    . ILE A 1 249 ? 20.12107  -10.73274 -13.32577 1.000 22.18105  ? 229 ILE A O    1 
ATOM   3478 C  CB   . ILE A 1 249 ? 21.84758  -8.07628  -12.28974 1.000 22.60358  ? 229 ILE A CB   1 
ATOM   3479 C  CG1  . ILE A 1 249 ? 22.65487  -7.53483  -11.12509 1.000 24.04212  ? 229 ILE A CG1  1 
ATOM   3480 C  CG2  . ILE A 1 249 ? 20.36337  -7.80603  -12.00856 1.000 22.56342  ? 229 ILE A CG2  1 
ATOM   3481 C  CD1  . ILE A 1 249 ? 22.73863  -6.02883  -11.05779 1.000 31.73990  ? 229 ILE A CD1  1 
ATOM   3482 H  H    . ILE A 1 249 ? 23.94580  -9.12880  -12.96122 1.000 24.93828  ? 229 ILE A H    1 
ATOM   3483 H  HA   . ILE A 1 249 ? 21.81924  -10.04263 -11.67371 1.000 24.68438  ? 229 ILE A HA   1 
ATOM   3484 H  HB   . ILE A 1 249 ? 22.13476  -7.63498  -13.10441 1.000 27.14806  ? 229 ILE A HB   1 
ATOM   3485 H  HG12 . ILE A 1 249 ? 22.24793  -7.84133  -10.29965 1.000 28.87430  ? 229 ILE A HG12 1 
ATOM   3486 H  HG13 . ILE A 1 249 ? 23.56086  -7.87437  -11.19438 1.000 28.87430  ? 229 ILE A HG13 1 
ATOM   3487 H  HG21 . ILE A 1 249 ? 20.23488  -6.85336  -11.87889 1.000 27.09986  ? 229 ILE A HG21 1 
ATOM   3488 H  HG22 . ILE A 1 249 ? 19.83808  -8.11071  -12.76496 1.000 27.09986  ? 229 ILE A HG22 1 
ATOM   3489 H  HG23 . ILE A 1 249 ? 20.10086  -8.28717  -11.20826 1.000 27.09986  ? 229 ILE A HG23 1 
ATOM   3490 H  HD11 . ILE A 1 249 ? 23.39539  -5.77863  -10.38923 1.000 38.11164  ? 229 ILE A HD11 1 
ATOM   3491 H  HD12 . ILE A 1 249 ? 23.00440  -5.68820  -11.92626 1.000 38.11164  ? 229 ILE A HD12 1 
ATOM   3492 H  HD13 . ILE A 1 249 ? 21.86867  -5.67466  -10.81566 1.000 38.11164  ? 229 ILE A HD13 1 
ATOM   3493 N  N    . GLY A 1 250 ? 21.59095  -10.04243 -14.86884 1.000 19.40145  ? 230 GLY A N    1 
ATOM   3494 C  CA   . GLY A 1 250 ? 20.91182  -10.79589 -15.89896 1.000 20.19791  ? 230 GLY A CA   1 
ATOM   3495 C  C    . GLY A 1 250 ? 20.91238  -12.27410 -15.58269 1.000 22.75840  ? 230 GLY A C    1 
ATOM   3496 O  O    . GLY A 1 250 ? 19.88388  -12.95454 -15.69669 1.000 22.62545  ? 230 GLY A O    1 
ATOM   3497 H  H    . GLY A 1 250 ? 22.23256  -9.53901  -15.14177 1.000 23.30551  ? 230 GLY A H    1 
ATOM   3498 H  HA2  . GLY A 1 250 ? 19.99298  -10.49364 -15.97165 1.000 24.26126  ? 230 GLY A HA2  1 
ATOM   3499 H  HA3  . GLY A 1 250 ? 21.35734  -10.65960 -16.74975 1.000 24.26126  ? 230 GLY A HA3  1 
ATOM   3500 N  N    . GLY A 1 251 ? 22.04472  -12.78176 -15.13324 1.000 20.68917  ? 231 GLY A N    1 
ATOM   3501 C  CA   . GLY A 1 251 ? 22.13497  -14.20388 -14.87187 1.000 23.21514  ? 231 GLY A CA   1 
ATOM   3502 C  C    . GLY A 1 251 ? 21.24495  -14.66306 -13.73478 1.000 24.06407  ? 231 GLY A C    1 
ATOM   3503 O  O    . GLY A 1 251 ? 20.69505  -15.76473 -13.77930 1.000 27.25057  ? 231 GLY A O    1 
ATOM   3504 H  H    . GLY A 1 251 ? 22.76190  -12.33466 -14.97404 1.000 24.85076  ? 231 GLY A H    1 
ATOM   3505 H  HA2  . GLY A 1 251 ? 21.87846  -14.69020 -15.67100 1.000 27.88193  ? 231 GLY A HA2  1 
ATOM   3506 H  HA3  . GLY A 1 251 ? 23.05159  -14.42749 -14.64668 1.000 27.88193  ? 231 GLY A HA3  1 
ATOM   3507 N  N    . ASP A 1 252 ? 21.07273  -13.83934 -12.70523 1.000 20.39161  ? 232 ASP A N    1 
ATOM   3508 C  CA   . ASP A 1 252 ? 20.45105  -14.37290 -11.50549 1.000 17.98180  ? 232 ASP A CA   1 
ATOM   3509 C  C    . ASP A 1 252 ? 19.17379  -13.67770 -11.09920 1.000 22.10855  ? 232 ASP A C    1 
ATOM   3510 O  O    . ASP A 1 252 ? 18.60898  -14.06417 -10.07658 1.000 20.47804  ? 232 ASP A O    1 
ATOM   3511 C  CB   . ASP A 1 252 ? 21.44355  -14.39997 -10.32988 1.000 19.83917  ? 232 ASP A CB   1 
ATOM   3512 C  CG   . ASP A 1 252 ? 21.86763  -13.02057 -9.80801  1.000 22.12911  ? 232 ASP A CG   1 
ATOM   3513 O  OD1  . ASP A 1 252 ? 21.24291  -12.01032 -10.14569 1.000 20.02200  ? 232 ASP A OD1  1 
ATOM   3514 O  OD2  . ASP A 1 252 ? 22.83469  -12.95108 -8.98120  1.000 23.03506  ? 232 ASP A OD2  1 
ATOM   3515 H  H    . ASP A 1 252 ? 21.29758  -13.00957 -12.68217 1.000 24.49369  ? 232 ASP A H    1 
ATOM   3516 H  HA   . ASP A 1 252 ? 20.20658  -15.28998 -11.70573 1.000 21.60192  ? 232 ASP A HA   1 
ATOM   3517 H  HB2  . ASP A 1 252 ? 21.03265  -14.87614 -9.59142  1.000 23.83077  ? 232 ASP A HB2  1 
ATOM   3518 H  HB3  . ASP A 1 252 ? 22.24705  -14.86174 -10.61633 1.000 23.83077  ? 232 ASP A HB3  1 
ATOM   3519 N  N    . GLU A 1 253 ? 18.66120  -12.73409 -11.89207 1.000 20.10378  ? 233 GLU A N    1 
ATOM   3520 C  CA   . GLU A 1 253 ? 17.38773  -12.09299 -11.54645 1.000 20.92540  ? 233 GLU A CA   1 
ATOM   3521 C  C    . GLU A 1 253 ? 16.31789  -12.17261 -12.62826 1.000 21.25634  ? 233 GLU A C    1 
ATOM   3522 O  O    . GLU A 1 253 ? 15.22764  -11.62882 -12.41894 1.000 22.67293  ? 233 GLU A O    1 
ATOM   3523 C  CB   . GLU A 1 253 ? 17.61000  -10.61078 -11.21694 1.000 22.41378  ? 233 GLU A CB   1 
ATOM   3524 C  CG   . GLU A 1 253 ? 18.42401  -10.36385 -9.95950  1.000 23.20941  ? 233 GLU A CG   1 
ATOM   3525 C  CD   . GLU A 1 253 ? 17.77635  -10.88862 -8.69595  1.000 27.79485  ? 233 GLU A CD   1 
ATOM   3526 O  OE1  . GLU A 1 253 ? 16.52331  -11.07849 -8.65155  1.000 27.05681  ? 233 GLU A OE1  1 
ATOM   3527 O  OE2  . GLU A 1 253 ? 18.51897  -11.05918 -7.70611  1.000 27.14666  ? 233 GLU A OE2  1 
ATOM   3528 H  H    . GLU A 1 253 ? 19.02317  -12.45322 -12.61987 1.000 24.14829  ? 233 GLU A H    1 
ATOM   3529 H  HA   . GLU A 1 253 ? 17.04466  -12.54823 -10.76161 1.000 25.13424  ? 233 GLU A HA   1 
ATOM   3530 H  HB2  . GLU A 1 253 ? 18.08036  -10.19640 -11.95718 1.000 26.92030  ? 233 GLU A HB2  1 
ATOM   3531 H  HB3  . GLU A 1 253 ? 16.74559  -10.18796 -11.09478 1.000 26.92030  ? 233 GLU A HB3  1 
ATOM   3532 H  HG2  . GLU A 1 253 ? 19.28412  -10.80222 -10.05404 1.000 27.87506  ? 233 GLU A HG2  1 
ATOM   3533 H  HG3  . GLU A 1 253 ? 18.54887  -9.40797  -9.85185  1.000 27.87506  ? 233 GLU A HG3  1 
ATOM   3534 N  N    . THR A 1 254 ? 16.58295  -12.80633 -13.77051 1.000 18.73708  ? 234 THR A N    1 
ATOM   3535 C  CA   . THR A 1 254 ? 15.65031  -12.83458 -14.89899 1.000 20.30848  ? 234 THR A CA   1 
ATOM   3536 C  C    . THR A 1 254 ? 15.14812  -14.24595 -15.17699 1.000 19.24452  ? 234 THR A C    1 
ATOM   3537 O  O    . THR A 1 254 ? 13.93685  -14.49515 -15.07313 1.000 18.63678  ? 234 THR A O    1 
ATOM   3538 C  CB   . THR A 1 254 ? 16.28956  -12.25634 -16.17006 1.000 20.67569  ? 234 THR A CB   1 
ATOM   3539 O  OG1  . THR A 1 254 ? 17.43363  -13.06133 -16.53523 1.000 20.40925  ? 234 THR A OG1  1 
ATOM   3540 C  CG2  . THR A 1 254 ? 16.68196  -10.80023 -15.97274 1.000 20.93886  ? 234 THR A CG2  1 
ATOM   3541 H  H    . THR A 1 254 ? 17.31196  -13.23710 -13.92080 1.000 22.50825  ? 234 THR A H    1 
ATOM   3542 H  HA   . THR A 1 254 ? 14.89626  -12.27886 -14.64701 1.000 24.39394  ? 234 THR A HA   1 
ATOM   3543 H  HB   . THR A 1 254 ? 15.65126  -12.27394 -16.90024 1.000 24.83459  ? 234 THR A HB   1 
ATOM   3544 H  HG1  . THR A 1 254 ? 17.96637  -13.11382 -15.88791 1.000 24.51486  ? 234 THR A HG1  1 
ATOM   3545 H  HG21 . THR A 1 254 ? 17.11212  -10.46115 -16.77329 1.000 25.15039  ? 234 THR A HG21 1 
ATOM   3546 H  HG22 . THR A 1 254 ? 15.89342  -10.26613 -15.78880 1.000 25.15039  ? 234 THR A HG22 1 
ATOM   3547 H  HG23 . THR A 1 254 ? 17.29713  -10.72054 -15.22701 1.000 25.15039  ? 234 THR A HG23 1 
ATOM   3548 N  N    . THR A 1 255 ? 16.03566  -15.16752 -15.58433 1.000 18.05461  ? 235 THR A N    1 
ATOM   3549 C  CA   . THR A 1 255 ? 15.62948  -16.48388 -16.05488 1.000 18.29975  ? 235 THR A CA   1 
ATOM   3550 C  C    . THR A 1 255 ? 14.78857  -17.19958 -15.03953 1.000 18.24845  ? 235 THR A C    1 
ATOM   3551 O  O    . THR A 1 255 ? 13.87889  -17.94771 -15.41325 1.000 19.22196  ? 235 THR A O    1 
ATOM   3552 C  CB   . THR A 1 255 ? 16.89021  -17.29145 -16.36294 1.000 18.36195  ? 235 THR A CB   1 
ATOM   3553 O  OG1  . THR A 1 255 ? 17.70972  -16.51162 -17.23111 1.000 20.26552  ? 235 THR A OG1  1 
ATOM   3554 C  CG2  . THR A 1 255 ? 16.58669  -18.66069 -16.96399 1.000 23.52915  ? 235 THR A CG2  1 
ATOM   3555 H  H    . THR A 1 255 ? 16.88711  -15.04706 -15.59541 1.000 21.68929  ? 235 THR A H    1 
ATOM   3556 H  HA   . THR A 1 255 ? 15.09631  -16.39355 -16.86017 1.000 21.98346  ? 235 THR A HA   1 
ATOM   3557 H  HB   . THR A 1 255 ? 17.36580  -17.48422 -15.53980 1.000 22.05811  ? 235 THR A HB   1 
ATOM   3558 H  HG1  . THR A 1 255 ? 18.39886  -16.94379 -17.44068 1.000 24.34238  ? 235 THR A HG1  1 
ATOM   3559 H  HG21 . THR A 1 255 ? 17.41328  -19.10980 -17.20052 1.000 28.25875  ? 235 THR A HG21 1 
ATOM   3560 H  HG22 . THR A 1 255 ? 16.10500  -19.20542 -16.32201 1.000 28.25875  ? 235 THR A HG22 1 
ATOM   3561 H  HG23 . THR A 1 255 ? 16.04379  -18.55996 -17.76150 1.000 28.25875  ? 235 THR A HG23 1 
ATOM   3562 N  N    . ARG A 1 256 ? 15.09629  -17.00496 -13.75141 1.000 17.51134  ? 236 ARG A N    1 
ATOM   3563 C  CA   . ARG A 1 256 ? 14.33441  -17.60444 -12.66644 1.000 16.94607  ? 236 ARG A CA   1 
ATOM   3564 C  C    . ARG A 1 256 ? 12.82656  -17.41562 -12.86817 1.000 18.88121  ? 236 ARG A C    1 
ATOM   3565 O  O    . ARG A 1 256 ? 12.04253  -18.30297 -12.54385 1.000 18.42466  ? 236 ARG A O    1 
ATOM   3566 C  CB   . ARG A 1 256 ? 14.77280  -16.99169 -11.32183 1.000 18.97723  ? 236 ARG A CB   1 
ATOM   3567 C  CG   . ARG A 1 256 ? 14.53855  -15.48780 -11.21340 1.000 19.21651  ? 236 ARG A CG   1 
ATOM   3568 C  CD   . ARG A 1 256 ? 15.32867  -14.81409 -10.12457 1.000 21.61909  ? 236 ARG A CD   1 
ATOM   3569 N  NE   . ARG A 1 256 ? 14.86017  -15.15716 -8.79080  1.000 23.39111  ? 236 ARG A NE   1 
ATOM   3570 C  CZ   . ARG A 1 256 ? 15.47225  -14.75968 -7.66442  1.000 26.37057  ? 236 ARG A CZ   1 
ATOM   3571 N  NH1  . ARG A 1 256 ? 16.62997  -14.11804 -7.68270  1.000 25.27324  ? 236 ARG A NH1  1 
ATOM   3572 N  NH2  . ARG A 1 256 ? 14.89739  -14.99288 -6.49301  1.000 27.85193  ? 236 ARG A NH2  1 
ATOM   3573 H  H    . ARG A 1 256 ? 15.75345  -16.52109 -13.48012 1.000 21.03737  ? 236 ARG A H    1 
ATOM   3574 H  HA   . ARG A 1 256 ? 14.51728  -18.55681 -12.64509 1.000 20.35905  ? 236 ARG A HA   1 
ATOM   3575 H  HB2  . ARG A 1 256 ? 14.27336  -17.41939 -10.60871 1.000 22.79644  ? 236 ARG A HB2  1 
ATOM   3576 H  HB3  . ARG A 1 256 ? 15.72232  -17.15082 -11.20352 1.000 22.79644  ? 236 ARG A HB3  1 
ATOM   3577 H  HG2  . ARG A 1 256 ? 14.78698  -15.07350 -12.05455 1.000 23.08358  ? 236 ARG A HG2  1 
ATOM   3578 H  HG3  . ARG A 1 256 ? 13.59844  -15.33236 -11.03192 1.000 23.08358  ? 236 ARG A HG3  1 
ATOM   3579 H  HD2  . ARG A 1 256 ? 16.25741  -15.08514 -10.19441 1.000 25.96666  ? 236 ARG A HD2  1 
ATOM   3580 H  HD3  . ARG A 1 256 ? 15.25488  -13.85262 -10.22953 1.000 25.96666  ? 236 ARG A HD3  1 
ATOM   3581 H  HE   . ARG A 1 256 ? 14.15263  -15.64091 -8.72021  1.000 28.09310  ? 236 ARG A HE   1 
ATOM   3582 H  HH11 . ARG A 1 256 ? 17.01322  -13.94377 -8.43260  1.000 30.35165  ? 236 ARG A HH11 1 
ATOM   3583 H  HH12 . ARG A 1 256 ? 16.99885  -13.87546 -6.94467  1.000 30.35165  ? 236 ARG A HH12 1 
ATOM   3584 H  HH21 . ARG A 1 256 ? 14.13840  -15.39584 -6.45912  1.000 33.44607  ? 236 ARG A HH21 1 
ATOM   3585 H  HH22 . ARG A 1 256 ? 15.28342  -14.74120 -5.76690  1.000 33.44607  ? 236 ARG A HH22 1 
ATOM   3586 N  N    . HIS A 1 257 ? 12.40440  -16.25130 -13.33417 1.000 17.24914  ? 237 HIS A N    1 
ATOM   3587 C  CA   . HIS A 1 257 ? 10.97677  -15.96227 -13.46216 1.000 16.82794  ? 237 HIS A CA   1 
ATOM   3588 C  C    . HIS A 1 257 ? 10.33805  -16.62978 -14.66256 1.000 17.02832  ? 237 HIS A C    1 
ATOM   3589 O  O    . HIS A 1 257 ? 9.13015   -16.90447 -14.61861 1.000 18.57022  ? 237 HIS A O    1 
ATOM   3590 C  CB   . HIS A 1 257 ? 10.76944  -14.44991 -13.52998 1.000 17.66160  ? 237 HIS A CB   1 
ATOM   3591 C  CG   . HIS A 1 257 ? 11.27337  -13.73442 -12.31517 1.000 17.86493  ? 237 HIS A CG   1 
ATOM   3592 N  ND1  . HIS A 1 257 ? 10.91449  -14.08958 -11.03616 1.000 19.57450  ? 237 HIS A ND1  1 
ATOM   3593 C  CD2  . HIS A 1 257 ? 12.13983  -12.69679 -12.18070 1.000 20.37734  ? 237 HIS A CD2  1 
ATOM   3594 C  CE1  . HIS A 1 257 ? 11.55107  -13.32058 -10.15886 1.000 20.99594  ? 237 HIS A CE1  1 
ATOM   3595 N  NE2  . HIS A 1 257 ? 12.28099  -12.44811 -10.83105 1.000 21.39028  ? 237 HIS A NE2  1 
ATOM   3596 H  H    . HIS A 1 257 ? 12.91943  -15.60952 -13.58408 1.000 20.72273  ? 237 HIS A H    1 
ATOM   3597 H  HA   . HIS A 1 257 ? 10.51657  -16.29711 -12.67666 1.000 20.21729  ? 237 HIS A HA   1 
ATOM   3598 H  HB2  . HIS A 1 257 ? 11.24415  -14.10148 -14.30078 1.000 21.21768  ? 237 HIS A HB2  1 
ATOM   3599 H  HB3  . HIS A 1 257 ? 9.82074   -14.26580 -13.61353 1.000 21.21768  ? 237 HIS A HB3  1 
ATOM   3600 H  HD1  . HIS A 1 257 ? 10.36078  -14.71582 -10.83411 1.000 23.51317  ? 237 HIS A HD1  1 
ATOM   3601 H  HD2  . HIS A 1 257 ? 12.56066  -12.23819 -12.87171 1.000 24.47658  ? 237 HIS A HD2  1 
ATOM   3602 H  HE1  . HIS A 1 257 ? 11.49290  -13.38529 -9.23294  1.000 25.21889  ? 237 HIS A HE1  1 
ATOM   3603 N  N    . THR A 1 258 ? 11.12659  -16.93794 -15.69962 1.000 17.78895  ? 238 THR A N    1 
ATOM   3604 C  CA   . THR A 1 258 ? 10.58059  -17.74177 -16.79670 1.000 16.10631  ? 238 THR A CA   1 
ATOM   3605 C  C    . THR A 1 258 ? 10.53113  -19.20717 -16.39623 1.000 18.90326  ? 238 THR A C    1 
ATOM   3606 O  O    . THR A 1 258 ? 9.56773   -19.90568 -16.71050 1.000 19.16963  ? 238 THR A O    1 
ATOM   3607 C  CB   . THR A 1 258 ? 11.39231  -17.53866 -18.06269 1.000 17.31657  ? 238 THR A CB   1 
ATOM   3608 O  OG1  . THR A 1 258 ? 11.31621  -16.14988 -18.44200 1.000 18.65063  ? 238 THR A OG1  1 
ATOM   3609 C  CG2  . THR A 1 258 ? 10.80750  -18.38818 -19.19833 1.000 20.03689  ? 238 THR A CG2  1 
ATOM   3610 H  H    . THR A 1 258 ? 11.94905  -16.70266 -15.78790 1.000 21.37050  ? 238 THR A H    1 
ATOM   3611 H  HA   . THR A 1 258 ? 9.67874   -17.44870 -17.00084 1.000 19.35134  ? 238 THR A HA   1 
ATOM   3612 H  HB   . THR A 1 258 ? 12.31526  -17.79816 -17.91533 1.000 20.80365  ? 238 THR A HB   1 
ATOM   3613 H  HG1  . THR A 1 258 ? 10.51971  -15.88549 -18.40613 1.000 22.40452  ? 238 THR A HG1  1 
ATOM   3614 H  HG21 . THR A 1 258 ? 11.24234  -18.16616 -20.03649 1.000 24.06803  ? 238 THR A HG21 1 
ATOM   3615 H  HG22 . THR A 1 258 ? 10.94468  -19.33026 -19.01239 1.000 24.06803  ? 238 THR A HG22 1 
ATOM   3616 H  HG23 . THR A 1 258 ? 9.85607   -18.21928 -19.28288 1.000 24.06803  ? 238 THR A HG23 1 
ATOM   3617 N  N    . LEU A 1 259 ? 11.51920  -19.67986 -15.63601 1.000 17.10585  ? 239 LEU A N    1 
ATOM   3618 C  CA   . LEU A 1 259 ? 11.45951  -21.05508 -15.13612 1.000 19.23993  ? 239 LEU A CA   1 
ATOM   3619 C  C    . LEU A 1 259 ? 10.21716  -21.27802 -14.28272 1.000 21.56665  ? 239 LEU A C    1 
ATOM   3620 O  O    . LEU A 1 259 ? 9.50131   -22.26335 -14.47462 1.000 20.93364  ? 239 LEU A O    1 
ATOM   3621 C  CB   . LEU A 1 259 ? 12.72107  -21.34052 -14.30571 1.000 21.84686  ? 239 LEU A CB   1 
ATOM   3622 C  CG   . LEU A 1 259 ? 13.90598  -21.87534 -15.08898 1.000 24.99621  ? 239 LEU A CG   1 
ATOM   3623 C  CD1  . LEU A 1 259 ? 15.11532  -22.01538 -14.13545 1.000 25.54255  ? 239 LEU A CD1  1 
ATOM   3624 C  CD2  . LEU A 1 259 ? 13.60377  -23.22744 -15.75706 1.000 25.19782  ? 239 LEU A CD2  1 
ATOM   3625 H  H    . LEU A 1 259 ? 12.21802  -19.23747 -15.40034 1.000 20.55078  ? 239 LEU A H    1 
ATOM   3626 H  HA   . LEU A 1 259 ? 11.42382  -21.66561 -15.88903 1.000 23.11168  ? 239 LEU A HA   1 
ATOM   3627 H  HB2  . LEU A 1 259 ? 13.00182  -20.51373 -13.88323 1.000 26.24000  ? 239 LEU A HB2  1 
ATOM   3628 H  HB3  . LEU A 1 259 ? 12.49872  -21.99967 -13.62970 1.000 26.24000  ? 239 LEU A HB3  1 
ATOM   3629 H  HG   . LEU A 1 259 ? 14.11217  -21.25234 -15.80330 1.000 30.01922  ? 239 LEU A HG   1 
ATOM   3630 H  HD11 . LEU A 1 259 ? 15.87260  -22.35972 -14.63431 1.000 30.67482  ? 239 LEU A HD11 1 
ATOM   3631 H  HD12 . LEU A 1 259 ? 15.33014  -21.14386 -13.76775 1.000 30.67482  ? 239 LEU A HD12 1 
ATOM   3632 H  HD13 . LEU A 1 259 ? 14.88414  -22.62836 -13.42011 1.000 30.67482  ? 239 LEU A HD13 1 
ATOM   3633 H  HD21 . LEU A 1 259 ? 14.43180  -23.60700 -16.09052 1.000 30.26114  ? 239 LEU A HD21 1 
ATOM   3634 H  HD22 . LEU A 1 259 ? 13.20776  -23.82228 -15.10112 1.000 30.26114  ? 239 LEU A HD22 1 
ATOM   3635 H  HD23 . LEU A 1 259 ? 12.98560  -23.08586 -16.49103 1.000 30.26114  ? 239 LEU A HD23 1 
ATOM   3636 N  N    . SER A 1 260 ? 9.94905   -20.37435 -13.34287 1.000 20.18683  ? 240 SER A N    1 
ATOM   3637 C  CA   . SER A 1 260 ? 8.82333   -20.56323 -12.42606 1.000 19.28951  ? 240 SER A CA   1 
ATOM   3638 C  C    . SER A 1 260 ? 7.50724   -20.30994 -13.14979 1.000 19.89712  ? 240 SER A C    1 
ATOM   3639 O  O    . SER A 1 260 ? 6.61097   -21.16225 -13.13490 1.000 20.32278  ? 240 SER A O    1 
ATOM   3640 C  CB   . SER A 1 260 ? 8.97315   -19.67052 -11.18666 1.000 19.84169  ? 240 SER A CB   1 
ATOM   3641 O  OG   . SER A 1 260 ? 8.94146   -18.33285 -11.58526 1.000 19.72533  ? 240 SER A OG   1 
ATOM   3642 H  H    . SER A 1 260 ? 10.39649  -19.65123 -13.21439 1.000 24.24796  ? 240 SER A H    1 
ATOM   3643 H  HA   . SER A 1 260 ? 8.82138   -21.47865 -12.10527 1.000 23.17118  ? 240 SER A HA   1 
ATOM   3644 H  HB2  . SER A 1 260 ? 8.24129   -19.84271 -10.57377 1.000 23.83380  ? 240 SER A HB2  1 
ATOM   3645 H  HB3  . SER A 1 260 ? 9.82021   -19.85873 -10.75310 1.000 23.83380  ? 240 SER A HB3  1 
ATOM   3646 H  HG   . SER A 1 260 ? 9.04435   -17.83197 -10.91883 1.000 23.69416  ? 240 SER A HG   1 
ATOM   3647 N  N    . GLY A 1 261 ? 7.37370   -19.15907 -13.80095 1.000 19.17487  ? 241 GLY A N    1 
ATOM   3648 C  CA   . GLY A 1 261 ? 6.09908   -18.81966 -14.41675 1.000 18.44727  ? 241 GLY A CA   1 
ATOM   3649 C  C    . GLY A 1 261 ? 5.78307   -19.67573 -15.63052 1.000 20.18105  ? 241 GLY A C    1 
ATOM   3650 O  O    . GLY A 1 261 ? 4.59864   -19.94932 -15.91521 1.000 19.86408  ? 241 GLY A O    1 
ATOM   3651 H  H    . GLY A 1 261 ? 7.99258   -18.56995 -13.89852 1.000 23.03360  ? 241 GLY A H    1 
ATOM   3652 H  HA2  . GLY A 1 261 ? 5.38898   -18.93993 -13.76698 1.000 22.16048  ? 241 GLY A HA2  1 
ATOM   3653 H  HA3  . GLY A 1 261 ? 6.11730   -17.89102 -14.69639 1.000 22.16048  ? 241 GLY A HA3  1 
ATOM   3654 N  N    . GLY A 1 262 ? 6.81497   -20.10185 -16.36218 1.000 19.43135  ? 242 GLY A N    1 
ATOM   3655 C  CA   . GLY A 1 262 ? 6.60184   -20.98097 -17.50960 1.000 19.48811  ? 242 GLY A CA   1 
ATOM   3656 C  C    . GLY A 1 262 ? 6.15317   -22.35930 -17.05749 1.000 21.51702  ? 242 GLY A C    1 
ATOM   3657 O  O    . GLY A 1 262 ? 5.19367   -22.91889 -17.59734 1.000 20.20839  ? 242 GLY A O    1 
ATOM   3658 H  H    . GLY A 1 262 ? 7.63804   -19.89907 -16.21713 1.000 23.34138  ? 242 GLY A H    1 
ATOM   3659 H  HA2  . GLY A 1 262 ? 5.92001   -20.60463 -18.08786 1.000 23.40950  ? 242 GLY A HA2  1 
ATOM   3660 H  HA3  . GLY A 1 262 ? 7.42729   -21.07013 -18.01118 1.000 23.40950  ? 242 GLY A HA3  1 
ATOM   3661 N  N    . THR A 1 263 ? 6.83286   -22.91238 -16.05340 1.000 20.85728  ? 243 THR A N    1 
ATOM   3662 C  CA   . THR A 1 263 ? 6.41506   -24.20347 -15.52788 1.000 20.27820  ? 243 THR A CA   1 
ATOM   3663 C  C    . THR A 1 263 ? 5.01579   -24.11582 -14.94349 1.000 23.07076  ? 243 THR A C    1 
ATOM   3664 O  O    . THR A 1 263 ? 4.20845   -25.02697 -15.13307 1.000 21.15500  ? 243 THR A O    1 
ATOM   3665 C  CB   . THR A 1 263 ? 7.41536   -24.68469 -14.48439 1.000 20.31838  ? 243 THR A CB   1 
ATOM   3666 O  OG1  . THR A 1 263 ? 8.72131   -24.75051 -15.06516 1.000 22.31138  ? 243 THR A OG1  1 
ATOM   3667 C  CG2  . THR A 1 263 ? 7.04561   -26.02846 -13.95202 1.000 23.65934  ? 243 THR A CG2  1 
ATOM   3668 H  H    . THR A 1 263 ? 7.52136   -22.56769 -15.67028 1.000 25.05250  ? 243 THR A H    1 
ATOM   3669 H  HA   . THR A 1 263 ? 6.40063   -24.85664 -16.24486 1.000 24.35760  ? 243 THR A HA   1 
ATOM   3670 H  HB   . THR A 1 263 ? 7.41637   -24.06107 -13.74142 1.000 24.40582  ? 243 THR A HB   1 
ATOM   3671 H  HG1  . THR A 1 263 ? 8.95368   -23.99029 -15.33658 1.000 26.79742  ? 243 THR A HG1  1 
ATOM   3672 H  HG21 . THR A 1 263 ? 7.78059   -26.39441 -13.43551 1.000 28.41497  ? 243 THR A HG21 1 
ATOM   3673 H  HG22 . THR A 1 263 ? 6.26498   -25.95572 -13.38085 1.000 28.41497  ? 243 THR A HG22 1 
ATOM   3674 H  HG23 . THR A 1 263 ? 6.84458   -26.63170 -14.68455 1.000 28.41497  ? 243 THR A HG23 1 
ATOM   3675 N  N    . GLU A 1 264 ? 4.68734   -22.99750 -14.28654 1.000 22.75497  ? 244 GLU A N    1 
ATOM   3676 C  CA   . GLU A 1 264 ? 3.33897   -22.80113 -13.75182 1.000 21.82553  ? 244 GLU A CA   1 
ATOM   3677 C  C    . GLU A 1 264 ? 2.28423   -22.94191 -14.85766 1.000 22.25795  ? 244 GLU A C    1 
ATOM   3678 O  O    . GLU A 1 264 ? 1.24470   -23.56868 -14.65319 1.000 24.18931  ? 244 GLU A O    1 
ATOM   3679 C  CB   . GLU A 1 264 ? 3.21104   -21.42322 -13.10005 1.000 23.37273  ? 244 GLU A CB   1 
ATOM   3680 C  CG   . GLU A 1 264 ? 1.85015   -21.25654 -12.43953 1.000 24.41349  ? 244 GLU A CG   1 
ATOM   3681 C  CD   . GLU A 1 264 ? 1.45603   -19.81641 -12.09627 1.000 28.93453  ? 244 GLU A CD   1 
ATOM   3682 O  OE1  . GLU A 1 264 ? 2.06768   -18.85790 -12.61136 1.000 27.49521  ? 244 GLU A OE1  1 
ATOM   3683 O  OE2  . GLU A 1 264 ? 0.48645   -19.65749 -11.31576 1.000 32.86535  ? 244 GLU A OE2  1 
ATOM   3684 H  H    . GLU A 1 264 ? 5.22384   -22.34192 -14.13830 1.000 27.32972  ? 244 GLU A H    1 
ATOM   3685 H  HA   . GLU A 1 264 ? 3.18217   -23.47555 -13.07250 1.000 26.21440  ? 244 GLU A HA   1 
ATOM   3686 H  HB2  . GLU A 1 264 ? 3.89688   -21.32259 -12.42153 1.000 28.07104  ? 244 GLU A HB2  1 
ATOM   3687 H  HB3  . GLU A 1 264 ? 3.31081   -20.73581 -13.77711 1.000 28.07104  ? 244 GLU A HB3  1 
ATOM   3688 H  HG2  . GLU A 1 264 ? 1.17375   -21.60489 -13.04122 1.000 29.31994  ? 244 GLU A HG2  1 
ATOM   3689 H  HG3  . GLU A 1 264 ? 1.84877   -21.76104 -11.61105 1.000 29.31994  ? 244 GLU A HG3  1 
ATOM   3690 N  N    . GLN A 1 265 ? 2.53908   -22.35679 -16.03472 1.000 21.02432  ? 245 GLN A N    1 
ATOM   3691 C  CA   . GLN A 1 265 ? 1.56883   -22.50484 -17.11422 1.000 20.73593  ? 245 GLN A CA   1 
ATOM   3692 C  C    . GLN A 1 265 ? 1.46760   -23.93928 -17.60784 1.000 23.56644  ? 245 GLN A C    1 
ATOM   3693 O  O    . GLN A 1 265 ? 0.37051   -24.36660 -17.97615 1.000 24.65240  ? 245 GLN A O    1 
ATOM   3694 C  CB   . GLN A 1 265 ? 1.92300   -21.57637 -18.28678 1.000 20.61065  ? 245 GLN A CB   1 
ATOM   3695 C  CG   . GLN A 1 265 ? 1.65793   -20.10659 -18.00342 1.000 22.01870  ? 245 GLN A CG   1 
ATOM   3696 C  CD   . GLN A 1 265 ? 0.22762   -19.87221 -17.54152 1.000 24.57835  ? 245 GLN A CD   1 
ATOM   3697 O  OE1  . GLN A 1 265 ? -0.70914  -20.31570 -18.18652 1.000 31.01326  ? 245 GLN A OE1  1 
ATOM   3698 N  NE2  . GLN A 1 265 ? 0.06499   -19.20496 -16.43617 1.000 27.59920  ? 245 GLN A NE2  1 
ATOM   3699 H  H    . GLN A 1 265 ? 3.23674   -21.89006 -16.22190 1.000 25.25295  ? 245 GLN A H    1 
ATOM   3700 H  HA   . GLN A 1 265 ? 0.70053   -22.24424 -16.76919 1.000 24.90687  ? 245 GLN A HA   1 
ATOM   3701 H  HB2  . GLN A 1 265 ? 2.86687   -21.67396 -18.48804 1.000 24.75654  ? 245 GLN A HB2  1 
ATOM   3702 H  HB3  . GLN A 1 265 ? 1.39148   -21.83027 -19.05745 1.000 24.75654  ? 245 GLN A HB3  1 
ATOM   3703 H  HG2  . GLN A 1 265 ? 2.25741   -19.80209 -17.30428 1.000 26.44621  ? 245 GLN A HG2  1 
ATOM   3704 H  HG3  . GLN A 1 265 ? 1.80445   -19.59290 -18.81308 1.000 26.44621  ? 245 GLN A HG3  1 
ATOM   3705 H  HE21 . GLN A 1 265 ? 0.74990   -18.91849 -16.00208 1.000 33.14280  ? 245 GLN A HE21 1 
ATOM   3706 H  HE22 . GLN A 1 265 ? -0.72740  -19.05046 -16.13977 1.000 33.14280  ? 245 GLN A HE22 1 
ATOM   3707 N  N    . LEU A 1 266 ? 2.56777   -24.70492 -17.60124 1.000 22.60159  ? 246 LEU A N    1 
ATOM   3708 C  CA   . LEU A 1 266 ? 2.49144   -26.10961 -17.99547 1.000 22.61629  ? 246 LEU A CA   1 
ATOM   3709 C  C    . LEU A 1 266 ? 1.61469   -26.86726 -17.00837 1.000 23.77674  ? 246 LEU A C    1 
ATOM   3710 O  O    . LEU A 1 266 ? 0.85499   -27.77160 -17.38640 1.000 26.70466  ? 246 LEU A O    1 
ATOM   3711 C  CB   . LEU A 1 266 ? 3.89212   -26.73032 -18.04506 1.000 24.23166  ? 246 LEU A CB   1 
ATOM   3712 C  CG   . LEU A 1 266 ? 4.85905   -26.15232 -19.07032 1.000 23.59325  ? 246 LEU A CG   1 
ATOM   3713 C  CD1  . LEU A 1 266 ? 6.20046   -26.81159 -18.92606 1.000 26.31378  ? 246 LEU A CD1  1 
ATOM   3714 C  CD2  . LEU A 1 266 ? 4.31123   -26.39015 -20.48765 1.000 25.81119  ? 246 LEU A CD2  1 
ATOM   3715 H  H    . LEU A 1 266 ? 3.35355   -24.43723 -17.37651 1.000 27.14567  ? 246 LEU A H    1 
ATOM   3716 H  HA   . LEU A 1 266 ? 2.11265   -26.17692 -18.88592 1.000 27.16332  ? 246 LEU A HA   1 
ATOM   3717 H  HB2  . LEU A 1 266 ? 4.30128   -26.61739 -17.17285 1.000 29.10175  ? 246 LEU A HB2  1 
ATOM   3718 H  HB3  . LEU A 1 266 ? 3.79493   -27.67425 -18.24620 1.000 29.10175  ? 246 LEU A HB3  1 
ATOM   3719 H  HG   . LEU A 1 266 ? 4.96073   -25.19819 -18.92821 1.000 28.33566  ? 246 LEU A HG   1 
ATOM   3720 H  HD11 . LEU A 1 266 ? 6.81087   -26.43132 -19.57698 1.000 31.60029  ? 246 LEU A HD11 1 
ATOM   3721 H  HD12 . LEU A 1 266 ? 6.53427   -26.65536 -18.02881 1.000 31.60029  ? 246 LEU A HD12 1 
ATOM   3722 H  HD13 . LEU A 1 266 ? 6.10256   -27.76406 -19.08139 1.000 31.60029  ? 246 LEU A HD13 1 
ATOM   3723 H  HD21 . LEU A 1 266 ? 4.98809   -26.13653 -21.13452 1.000 30.99719  ? 246 LEU A HD21 1 
ATOM   3724 H  HD22 . LEU A 1 266 ? 4.09312   -27.32994 -20.58834 1.000 30.99719  ? 246 LEU A HD22 1 
ATOM   3725 H  HD23 . LEU A 1 266 ? 3.51503   -25.85051 -20.61316 1.000 30.99719  ? 246 LEU A HD23 1 
ATOM   3726 N  N    . LEU A 1 267 ? 1.73296   -26.52836 -15.72488 1.000 24.40315  ? 247 LEU A N    1 
ATOM   3727 C  CA   . LEU A 1 267 ? 0.98304   -27.23262 -14.68386 1.000 25.21488  ? 247 LEU A CA   1 
ATOM   3728 C  C    . LEU A 1 267 ? -0.48366  -26.81074 -14.64252 1.000 27.19638  ? 247 LEU A C    1 
ATOM   3729 O  O    . LEU A 1 267 ? -1.34448  -27.63923 -14.32402 1.000 33.26308  ? 247 LEU A O    1 
ATOM   3730 C  CB   . LEU A 1 267 ? 1.63282   -27.00556 -13.32420 1.000 26.22859  ? 247 LEU A CB   1 
ATOM   3731 C  CG   . LEU A 1 267 ? 3.06222   -27.51586 -13.20554 1.000 25.47815  ? 247 LEU A CG   1 
ATOM   3732 C  CD1  . LEU A 1 267 ? 3.59924   -27.13319 -11.81908 1.000 26.86867  ? 247 LEU A CD1  1 
ATOM   3733 C  CD2  . LEU A 1 267 ? 3.14601   -29.03498 -13.43701 1.000 30.65137  ? 247 LEU A CD2  1 
ATOM   3734 H  H    . LEU A 1 267 ? 2.23793   -25.89751 -15.43056 1.000 29.30754  ? 247 LEU A H    1 
ATOM   3735 H  HA   . LEU A 1 267 ? 1.01152   -28.18359 -14.87294 1.000 30.28162  ? 247 LEU A HA   1 
ATOM   3736 H  HB2  . LEU A 1 267 ? 1.64720   -26.05214 -13.14622 1.000 31.49807  ? 247 LEU A HB2  1 
ATOM   3737 H  HB3  . LEU A 1 267 ? 1.10321   -27.46077 -12.65100 1.000 31.49807  ? 247 LEU A HB3  1 
ATOM   3738 H  HG   . LEU A 1 267 ? 3.61569   -27.10982 -13.89089 1.000 30.59754  ? 247 LEU A HG   1 
ATOM   3739 H  HD11 . LEU A 1 267 ? 4.51518   -27.44225 -11.73885 1.000 32.26617  ? 247 LEU A HD11 1 
ATOM   3740 H  HD12 . LEU A 1 267 ? 3.56600   -26.16856 -11.72274 1.000 32.26617  ? 247 LEU A HD12 1 
ATOM   3741 H  HD13 . LEU A 1 267 ? 3.04794   -27.55263 -11.14008 1.000 32.26617  ? 247 LEU A HD13 1 
ATOM   3742 H  HD21 . LEU A 1 267 ? 4.03705   -29.34094 -13.20606 1.000 36.80540  ? 247 LEU A HD21 1 
ATOM   3743 H  HD22 . LEU A 1 267 ? 2.48900   -29.47655 -12.87643 1.000 36.80540  ? 247 LEU A HD22 1 
ATOM   3744 H  HD23 . LEU A 1 267 ? 2.96356   -29.22264 -14.37103 1.000 36.80540  ? 247 LEU A HD23 1 
ATOM   3745 N  N    . ARG A 1 268 ? -0.79014  -25.55530 -14.97306 1.000 25.41069  ? 248 ARG A N    1 
ATOM   3746 C  CA   . ARG A 1 268 ? -2.16258  -25.08226 -14.99418 1.000 28.98166  ? 248 ARG A CA   1 
ATOM   3747 C  C    . ARG A 1 268 ? -2.91780  -25.57659 -16.21742 1.000 30.91387  ? 248 ARG A C    1 
ATOM   3748 O  O    . ARG A 1 268 ? -4.15213  -25.67829 -16.16903 1.000 34.14406  ? 248 ARG A O    1 
ATOM   3749 C  CB   . ARG A 1 268 ? -2.19689  -23.56389 -14.95698 1.000 29.73146  ? 248 ARG A CB   1 
ATOM   3750 C  CG   . ARG A 1 268 ? -1.69869  -23.00956 -13.64732 1.000 33.32207  ? 248 ARG A CG   1 
ATOM   3751 C  CD   . ARG A 1 268 ? -2.23343  -21.63728 -13.33051 1.000 41.20094  ? 248 ARG A CD   1 
ATOM   3752 N  NE   . ARG A 1 268 ? -1.73992  -21.21187 -12.02409 1.000 48.08349  ? 248 ARG A NE   1 
ATOM   3753 C  CZ   . ARG A 1 268 ? -2.32788  -21.48578 -10.86372 1.000 44.92419  ? 248 ARG A CZ   1 
ATOM   3754 N  NH1  . ARG A 1 268 ? -3.45640  -22.17345 -10.80512 1.000 44.58434  ? 248 ARG A NH1  1 
ATOM   3755 N  NH2  . ARG A 1 268 ? -1.76084  -21.06415 -9.72961  1.000 41.55141  ? 248 ARG A NH2  1 
ATOM   3756 H  H    . ARG A 1 268 ? -0.21239  -24.95645 -15.19030 1.000 30.51659  ? 248 ARG A H    1 
ATOM   3757 H  HA   . ARG A 1 268 ? -2.61829  -25.40623 -14.20154 1.000 34.80175  ? 248 ARG A HA   1 
ATOM   3758 H  HB2  . ARG A 1 268 ? -1.63294  -23.21667 -15.66571 1.000 35.70151  ? 248 ARG A HB2  1 
ATOM   3759 H  HB3  . ARG A 1 268 ? -3.11078  -23.26433 -15.08336 1.000 35.70151  ? 248 ARG A HB3  1 
ATOM   3760 H  HG2  . ARG A 1 268 ? -1.97001  -23.60535 -12.93155 1.000 40.01024  ? 248 ARG A HG2  1 
ATOM   3761 H  HG3  . ARG A 1 268 ? -0.73111  -22.94972 -13.68034 1.000 40.01024  ? 248 ARG A HG3  1 
ATOM   3762 H  HD2  . ARG A 1 268 ? -1.93205  -21.00422 -14.00080 1.000 49.46489  ? 248 ARG A HD2  1 
ATOM   3763 H  HD3  . ARG A 1 268 ? -3.20290  -21.65953 -13.30733 1.000 49.46489  ? 248 ARG A HD3  1 
ATOM   3764 H  HE   . ARG A 1 268 ? -1.01494  -20.74972 -12.00366 1.000 57.72395  ? 248 ARG A HE   1 
ATOM   3765 H  HH11 . ARG A 1 268 ? -3.82671  -22.45456 -11.52862 1.000 53.52497  ? 248 ARG A HH11 1 
ATOM   3766 H  HH12 . ARG A 1 268 ? -3.81977  -22.33941 -10.04353 1.000 53.52497  ? 248 ARG A HH12 1 
ATOM   3767 H  HH21 . ARG A 1 268 ? -1.02416  -20.62119 -9.75599  1.000 49.88545  ? 248 ARG A HH21 1 
ATOM   3768 H  HH22 . ARG A 1 268 ? -2.13257  -21.23574 -8.97332  1.000 49.88545  ? 248 ARG A HH22 1 
ATOM   3769 N  N    . ASN A 1 269 ? -2.21028  -25.89352 -17.29850 1.000 30.04774  ? 249 ASN A N    1 
ATOM   3770 C  CA   . ASN A 1 269 ? -2.78283  -26.42373 -18.54119 1.000 31.79297  ? 249 ASN A CA   1 
ATOM   3771 C  C    . ASN A 1 269 ? -2.18004  -27.79527 -18.79064 1.000 28.89026  ? 249 ASN A C    1 
ATOM   3772 O  O    . ASN A 1 269 ? -1.22884  -27.90991 -19.56488 1.000 30.90192  ? 249 ASN A O    1 
ATOM   3773 C  CB   . ASN A 1 269 ? -2.45610  -25.43361 -19.71929 1.000 30.60873  ? 249 ASN A CB   1 
ATOM   3774 C  CG   . ASN A 1 269 ? -2.94294  -24.03327 -19.42802 1.000 37.51035  ? 249 ASN A CG   1 
ATOM   3775 O  OD1  . ASN A 1 269 ? -4.14679  -23.78287 -19.51051 1.000 37.11318  ? 249 ASN A OD1  1 
ATOM   3776 N  ND2  . ASN A 1 269 ? -2.02231  -23.10039 -19.13597 1.000 28.59601  ? 249 ASN A ND2  1 
ATOM   3777 H  H    . ASN A 1 269 ? -1.35570  -25.80706 -17.34115 1.000 36.08105  ? 249 ASN A H    1 
ATOM   3778 H  HA   . ASN A 1 269 ? -3.74323  -26.52470 -18.44989 1.000 38.17533  ? 249 ASN A HA   1 
ATOM   3779 H  HB2  . ASN A 1 269 ? -1.49575  -25.40003 -19.85153 1.000 36.75424  ? 249 ASN A HB2  1 
ATOM   3780 H  HB3  . ASN A 1 269 ? -2.89172  -25.74459 -20.52826 1.000 36.75424  ? 249 ASN A HB3  1 
ATOM   3781 H  HD21 . ASN A 1 269 ? -2.26670  -22.29369 -18.96534 1.000 34.33898  ? 249 ASN A HD21 1 
ATOM   3782 H  HD22 . ASN A 1 269 ? -1.18831  -23.30961 -19.11956 1.000 34.33898  ? 249 ASN A HD22 1 
ATOM   3783 N  N    . ARG A 1 270 ? -2.71708  -28.82427 -18.13260 1.000 30.21821  ? 250 ARG A N    1 
ATOM   3784 C  CA   . ARG A 1 270 ? -2.02573  -30.10551 -18.13071 1.000 31.09688  ? 250 ARG A CA   1 
ATOM   3785 C  C    . ARG A 1 270 ? -1.96371  -30.76228 -19.50112 1.000 30.82341  ? 250 ARG A C    1 
ATOM   3786 O  O    . ARG A 1 270 ? -1.08732  -31.60233 -19.71312 1.000 30.36268  ? 250 ARG A O    1 
ATOM   3787 C  CB   . ARG A 1 270 ? -2.63816  -31.06709 -17.11985 1.000 41.61459  ? 250 ARG A CB   1 
ATOM   3788 C  CG   . ARG A 1 270 ? -1.93771  -30.94400 -15.78509 1.000 47.32940  ? 250 ARG A CG   1 
ATOM   3789 C  CD   . ARG A 1 270 ? -2.00886  -32.21846 -14.96097 1.000 51.48790  ? 250 ARG A CD   1 
ATOM   3790 N  NE   . ARG A 1 270 ? -0.75906  -32.95596 -14.89157 1.000 49.12934  ? 250 ARG A NE   1 
ATOM   3791 C  CZ   . ARG A 1 270 ? 0.22905   -32.64856 -14.05933 1.000 38.05003  ? 250 ARG A CZ   1 
ATOM   3792 N  NH1  . ARG A 1 270 ? 0.21777   -31.52610 -13.36151 1.000 36.74298  ? 250 ARG A NH1  1 
ATOM   3793 N  NH2  . ARG A 1 270 ? 1.24504   -33.49334 -13.92084 1.000 41.02307  ? 250 ARG A NH2  1 
ATOM   3794 H  H    . ARG A 1 270 ? -3.45690  -28.80381 -17.69460 1.000 36.28561  ? 250 ARG A H    1 
ATOM   3795 H  HA   . ARG A 1 270 ? -1.11354  -29.93345 -17.84927 1.000 37.34002  ? 250 ARG A HA   1 
ATOM   3796 H  HB2  . ARG A 1 270 ? -3.57709  -30.85603 -16.99834 1.000 49.96126  ? 250 ARG A HB2  1 
ATOM   3797 H  HB3  . ARG A 1 270 ? -2.54143  -31.97819 -17.43834 1.000 49.96126  ? 250 ARG A HB3  1 
ATOM   3798 H  HG2  . ARG A 1 270 ? -1.00209  -30.73797 -15.93697 1.000 56.81905  ? 250 ARG A HG2  1 
ATOM   3799 H  HG3  . ARG A 1 270 ? -2.35509  -30.23339 -15.27348 1.000 56.81905  ? 250 ARG A HG3  1 
ATOM   3800 H  HD2  . ARG A 1 270 ? -2.26387  -31.98772 -14.05398 1.000 61.80925  ? 250 ARG A HD2  1 
ATOM   3801 H  HD3  . ARG A 1 270 ? -2.67410  -32.80518 -15.35355 1.000 61.80925  ? 250 ARG A HD3  1 
ATOM   3802 H  HE   . ARG A 1 270 ? -0.65346  -33.62787 -15.41787 1.000 58.97897  ? 250 ARG A HE   1 
ATOM   3803 H  HH11 . ARG A 1 270 ? -0.43908  -30.97676 -13.44128 1.000 44.11534  ? 250 ARG A HH11 1 
ATOM   3804 H  HH12 . ARG A 1 270 ? 0.86729   -31.34511 -12.82768 1.000 44.11534  ? 250 ARG A HH12 1 
ATOM   3805 H  HH21 . ARG A 1 270 ? 1.25702   -34.22834 -14.36718 1.000 49.25144  ? 250 ARG A HH21 1 
ATOM   3806 H  HH22 . ARG A 1 270 ? 1.89072   -33.30517 -13.38486 1.000 49.25144  ? 250 ARG A HH22 1 
ATOM   3807 N  N    . ASP A 1 271 ? -2.84076  -30.38472 -20.44375 1.000 31.12943  ? 251 ASP A N    1 
ATOM   3808 C  CA   . ASP A 1 271 ? -2.64264  -30.83530 -21.81763 1.000 32.24580  ? 251 ASP A CA   1 
ATOM   3809 C  C    . ASP A 1 271 ? -1.28213  -30.40022 -22.35097 1.000 30.59900  ? 251 ASP A C    1 
ATOM   3810 O  O    . ASP A 1 271 ? -0.66885  -31.12367 -23.15233 1.000 31.20145  ? 251 ASP A O    1 
ATOM   3811 C  CB   . ASP A 1 271 ? -3.75710  -30.29709 -22.72190 1.000 32.35657  ? 251 ASP A CB   1 
ATOM   3812 C  CG   . ASP A 1 271 ? -3.81389  -28.76422 -22.74411 1.000 35.78311  ? 251 ASP A CG   1 
ATOM   3813 O  OD1  . ASP A 1 271 ? -4.02037  -28.14006 -21.67322 1.000 39.95115  ? 251 ASP A OD1  1 
ATOM   3814 O  OD2  . ASP A 1 271 ? -3.63828  -28.16334 -23.83857 1.000 40.47689  ? 251 ASP A OD2  1 
ATOM   3815 H  H    . ASP A 1 271 ? -3.53025  -29.88740 -20.31382 1.000 37.37907  ? 251 ASP A H    1 
ATOM   3816 H  HA   . ASP A 1 271 ? -2.68573  -31.80417 -21.83573 1.000 38.71873  ? 251 ASP A HA   1 
ATOM   3817 H  HB2  . ASP A 1 271 ? -3.60461  -30.60489 -23.62904 1.000 38.85164  ? 251 ASP A HB2  1 
ATOM   3818 H  HB3  . ASP A 1 271 ? -4.61149  -30.62438 -22.39972 1.000 38.85164  ? 251 ASP A HB3  1 
ATOM   3819 N  N    . GLN A 1 272 ? -0.78404  -29.24368 -21.89743 1.000 27.94395  ? 252 GLN A N    1 
ATOM   3820 C  CA   . GLN A 1 272 ? 0.50281   -28.74726 -22.37462 1.000 25.56895  ? 252 GLN A CA   1 
ATOM   3821 C  C    . GLN A 1 272 ? 1.63873   -29.54606 -21.74722 1.000 28.83396  ? 252 GLN A C    1 
ATOM   3822 O  O    . GLN A 1 272 ? 2.57018   -29.97879 -22.43549 1.000 27.35957  ? 252 GLN A O    1 
ATOM   3823 C  CB   . GLN A 1 272 ? 0.62035   -27.25454 -22.09103 1.000 26.62336  ? 252 GLN A CB   1 
ATOM   3824 C  CG   . GLN A 1 272 ? -0.41411  -26.41127 -22.81119 1.000 26.68774  ? 252 GLN A CG   1 
ATOM   3825 C  CD   . GLN A 1 272 ? -0.15765  -26.36367 -24.29239 1.000 29.32708  ? 252 GLN A CD   1 
ATOM   3826 O  OE1  . GLN A 1 272 ? 0.79107   -25.71678 -24.70829 1.000 29.34919  ? 252 GLN A OE1  1 
ATOM   3827 N  NE2  . GLN A 1 272 ? -1.02962  -26.98788 -25.09554 1.000 32.52123  ? 252 GLN A NE2  1 
ATOM   3828 H  H    . GLN A 1 272 ? -1.16944  -28.73597 -21.32011 1.000 33.55651  ? 252 GLN A H    1 
ATOM   3829 H  HA   . GLN A 1 272 ? 0.56625   -28.85388 -23.33666 1.000 30.70650  ? 252 GLN A HA   1 
ATOM   3830 H  HB2  . GLN A 1 272 ? 0.50988   -27.10871 -21.13844 1.000 31.97180  ? 252 GLN A HB2  1 
ATOM   3831 H  HB3  . GLN A 1 272 ? 1.49756   -26.95184 -22.37347 1.000 31.97180  ? 252 GLN A HB3  1 
ATOM   3832 H  HG2  . GLN A 1 272 ? -1.29457  -26.79176 -22.66656 1.000 32.04905  ? 252 GLN A HG2  1 
ATOM   3833 H  HG3  . GLN A 1 272 ? -0.38393  -25.50469 -22.46753 1.000 32.04905  ? 252 GLN A HG3  1 
ATOM   3834 H  HE21 . GLN A 1 272 ? -1.70726  -27.39693 -24.75925 1.000 39.04924  ? 252 GLN A HE21 1 
ATOM   3835 H  HE22 . GLN A 1 272 ? -0.91170  -26.97952 -25.94738 1.000 39.04924  ? 252 GLN A HE22 1 
ATOM   3836 N  N    . TRP A 1 273 ? 1.56218   -29.76587 -20.43242 1.000 27.26251  ? 253 TRP A N    1 
ATOM   3837 C  CA   . TRP A 1 273 ? 2.49020   -30.66866 -19.75949 1.000 27.75742  ? 253 TRP A CA   1 
ATOM   3838 C  C    . TRP A 1 273 ? 2.54058   -32.03889 -20.44029 1.000 27.90379  ? 253 TRP A C    1 
ATOM   3839 O  O    . TRP A 1 273 ? 3.62604   -32.55686 -20.74358 1.000 29.17342  ? 253 TRP A O    1 
ATOM   3840 C  CB   . TRP A 1 273 ? 2.06305   -30.79904 -18.29197 1.000 28.28116  ? 253 TRP A CB   1 
ATOM   3841 C  CG   . TRP A 1 273 ? 2.87405   -31.74774 -17.44989 1.000 26.24122  ? 253 TRP A CG   1 
ATOM   3842 C  CD1  . TRP A 1 273 ? 2.62456   -33.06837 -17.21343 1.000 29.59560  ? 253 TRP A CD1  1 
ATOM   3843 C  CD2  . TRP A 1 273 ? 4.06582   -31.42857 -16.71658 1.000 25.94662  ? 253 TRP A CD2  1 
ATOM   3844 N  NE1  . TRP A 1 273 ? 3.59480   -33.58914 -16.39823 1.000 29.25058  ? 253 TRP A NE1  1 
ATOM   3845 C  CE2  . TRP A 1 273 ? 4.48832   -32.60506 -16.07488 1.000 27.03587  ? 253 TRP A CE2  1 
ATOM   3846 C  CE3  . TRP A 1 273 ? 4.80838   -30.26142 -16.54662 1.000 25.28844  ? 253 TRP A CE3  1 
ATOM   3847 C  CZ2  . TRP A 1 273 ? 5.62351   -32.64916 -15.25585 1.000 28.64495  ? 253 TRP A CZ2  1 
ATOM   3848 C  CZ3  . TRP A 1 273 ? 5.93734   -30.30110 -15.73807 1.000 24.29369  ? 253 TRP A CZ3  1 
ATOM   3849 C  CH2  . TRP A 1 273 ? 6.32837   -31.48911 -15.10085 1.000 24.93381  ? 253 TRP A CH2  1 
ATOM   3850 H  H    . TRP A 1 273 ? 0.98247   -29.40439 -19.91006 1.000 32.73877  ? 253 TRP A H    1 
ATOM   3851 H  HA   . TRP A 1 273 ? 3.38703   -30.30101 -19.79736 1.000 33.33267  ? 253 TRP A HA   1 
ATOM   3852 H  HB2  . TRP A 1 273 ? 2.12655   -29.92372 -17.87883 1.000 33.96115  ? 253 TRP A HB2  1 
ATOM   3853 H  HB3  . TRP A 1 273 ? 1.14463   -31.11039 -18.27007 1.000 33.96115  ? 253 TRP A HB3  1 
ATOM   3854 H  HD1  . TRP A 1 273 ? 1.90253   -33.54459 -17.55518 1.000 35.53848  ? 253 TRP A HD1  1 
ATOM   3855 H  HE1  . TRP A 1 273 ? 3.63565   -34.40582 -16.13183 1.000 35.12446  ? 253 TRP A HE1  1 
ATOM   3856 H  HE3  . TRP A 1 273 ? 4.55313   -29.47166 -16.96620 1.000 30.36988  ? 253 TRP A HE3  1 
ATOM   3857 H  HZ2  . TRP A 1 273 ? 5.88664   -33.43558 -14.83489 1.000 34.39770  ? 253 TRP A HZ2  1 
ATOM   3858 H  HZ3  . TRP A 1 273 ? 6.44156   -29.52906 -15.61717 1.000 29.17619  ? 253 TRP A HZ3  1 
ATOM   3859 H  HH2  . TRP A 1 273 ? 7.08518   -31.48650 -14.56035 1.000 29.94433  ? 253 TRP A HH2  1 
ATOM   3860 N  N    . ASP A 1 274 ? 1.37154   -32.63146 -20.69364 1.000 28.85523  ? 254 ASP A N    1 
ATOM   3861 C  CA   . ASP A 1 274 ? 1.30748   -33.97082 -21.27964 1.000 31.76283  ? 254 ASP A CA   1 
ATOM   3862 C  C    . ASP A 1 274 ? 1.92028   -34.00132 -22.68312 1.000 33.89565  ? 254 ASP A C    1 
ATOM   3863 O  O    . ASP A 1 274 ? 2.61659   -34.96376 -23.04154 1.000 36.25850  ? 254 ASP A O    1 
ATOM   3864 C  CB   . ASP A 1 274 ? -0.13769  -34.47737 -21.31441 1.000 34.87144  ? 254 ASP A CB   1 
ATOM   3865 C  CG   . ASP A 1 274 ? -0.70163  -34.74447 -19.92411 1.000 39.06090  ? 254 ASP A CG   1 
ATOM   3866 O  OD1  . ASP A 1 274 ? 0.09829   -34.90131 -18.98020 1.000 38.99916  ? 254 ASP A OD1  1 
ATOM   3867 O  OD2  . ASP A 1 274 ? -1.93723  -34.84631 -19.78520 1.000 40.07151  ? 254 ASP A OD2  1 
ATOM   3868 H  H    . ASP A 1 274 ? 0.60228   -32.28071 -20.53611 1.000 34.65004  ? 254 ASP A H    1 
ATOM   3869 H  HA   . ASP A 1 274 ? 1.81855   -34.57170 -20.71515 1.000 38.13916  ? 254 ASP A HA   1 
ATOM   3870 H  HB2  . ASP A 1 274 ? -0.69662  -33.80960 -21.74172 1.000 41.86949  ? 254 ASP A HB2  1 
ATOM   3871 H  HB3  . ASP A 1 274 ? -0.16994  -35.30711 -21.81579 1.000 41.86949  ? 254 ASP A HB3  1 
ATOM   3872 N  N    . LEU A 1 275 ? 1.71450   -32.93851 -23.46869 1.000 31.63300  ? 255 LEU A N    1 
ATOM   3873 C  CA   . LEU A 1 275 ? 2.28238   -32.89024 -24.81082 1.000 31.35225  ? 255 LEU A CA   1 
ATOM   3874 C  C    . LEU A 1 275 ? 3.79586   -32.93515 -24.74946 1.000 31.27898  ? 255 LEU A C    1 
ATOM   3875 O  O    . LEU A 1 275 ? 4.44945   -33.65493 -25.51052 1.000 34.56635  ? 255 LEU A O    1 
ATOM   3876 C  CB   . LEU A 1 275 ? 1.84123   -31.62120 -25.52696 1.000 35.57982  ? 255 LEU A CB   1 
ATOM   3877 C  CG   . LEU A 1 275 ? 0.61019   -31.62828 -26.42930 1.000 46.15844  ? 255 LEU A CG   1 
ATOM   3878 C  CD1  . LEU A 1 275 ? 0.32756   -30.17625 -26.88488 1.000 41.05040  ? 255 LEU A CD1  1 
ATOM   3879 C  CD2  . LEU A 1 275 ? 0.79374   -32.53215 -27.62993 1.000 48.41582  ? 255 LEU A CD2  1 
ATOM   3880 H  H    . LEU A 1 275 ? 1.25635   -32.24485 -23.24842 1.000 37.98336  ? 255 LEU A H    1 
ATOM   3881 H  HA   . LEU A 1 275 ? 1.95725   -33.65517 -25.31089 1.000 37.64646  ? 255 LEU A HA   1 
ATOM   3882 H  HB2  . LEU A 1 275 ? 1.66827   -30.95459 -24.84386 1.000 42.71954  ? 255 LEU A HB2  1 
ATOM   3883 H  HB3  . LEU A 1 275 ? 2.58136   -31.33846 -26.08657 1.000 42.71954  ? 255 LEU A HB3  1 
ATOM   3884 H  HG   . LEU A 1 275 ? -0.14866  -31.97656 -25.93560 1.000 55.41389  ? 255 LEU A HG   1 
ATOM   3885 H  HD11 . LEU A 1 275 ? -0.45229  -30.17238 -27.46170 1.000 49.28425  ? 255 LEU A HD11 1 
ATOM   3886 H  HD12 . LEU A 1 275 ? 0.16335   -29.62624 -26.10294 1.000 49.28425  ? 255 LEU A HD12 1 
ATOM   3887 H  HD13 . LEU A 1 275 ? 1.09862   -29.84137 -27.36884 1.000 49.28425  ? 255 LEU A HD13 1 
ATOM   3888 H  HD21 . LEU A 1 275 ? -0.01000  -32.50397 -28.17225 1.000 58.12274  ? 255 LEU A HD21 1 
ATOM   3889 H  HD22 . LEU A 1 275 ? 1.55279   -32.22011 -28.14702 1.000 58.12274  ? 255 LEU A HD22 1 
ATOM   3890 H  HD23 . LEU A 1 275 ? 0.95330   -33.43797 -27.32184 1.000 58.12274  ? 255 LEU A HD23 1 
ATOM   3891 N  N    . LEU A 1 276 ? 4.37432   -32.15494 -23.84125 1.000 30.96570  ? 256 LEU A N    1 
ATOM   3892 C  CA   . LEU A 1 276 ? 5.82345   -32.07242 -23.76826 1.000 32.53688  ? 256 LEU A CA   1 
ATOM   3893 C  C    . LEU A 1 276 ? 6.42696   -33.35528 -23.27053 1.000 36.55292  ? 256 LEU A C    1 
ATOM   3894 O  O    . LEU A 1 276 ? 7.52444   -33.72066 -23.69401 1.000 37.80405  ? 256 LEU A O    1 
ATOM   3895 C  CB   . LEU A 1 276 ? 6.22015   -30.93595 -22.83255 1.000 33.03006  ? 256 LEU A CB   1 
ATOM   3896 C  CG   . LEU A 1 276 ? 6.18798   -29.55077 -23.40176 1.000 36.80527  ? 256 LEU A CG   1 
ATOM   3897 C  CD1  . LEU A 1 276 ? 6.89333   -28.61491 -22.38665 1.000 34.17781  ? 256 LEU A CD1  1 
ATOM   3898 C  CD2  . LEU A 1 276 ? 6.84216   -29.52565 -24.76421 1.000 34.58931  ? 256 LEU A CD2  1 
ATOM   3899 H  H    . LEU A 1 276 ? 3.95570   -31.67182 -23.26596 1.000 37.18261  ? 256 LEU A H    1 
ATOM   3900 H  HA   . LEU A 1 276 ? 6.17104   -31.89214 -24.65572 1.000 39.06801  ? 256 LEU A HA   1 
ATOM   3901 H  HB2  . LEU A 1 276 ? 5.61368   -30.94592 -22.07558 1.000 39.65984  ? 256 LEU A HB2  1 
ATOM   3902 H  HB3  . LEU A 1 276 ? 7.12811   -31.09845 -22.53237 1.000 39.65984  ? 256 LEU A HB3  1 
ATOM   3903 H  HG   . LEU A 1 276 ? 5.28026   -29.23744 -23.53876 1.000 44.19008  ? 256 LEU A HG   1 
ATOM   3904 H  HD11 . LEU A 1 276 ? 6.78931   -27.69596 -22.67925 1.000 41.03713  ? 256 LEU A HD11 1 
ATOM   3905 H  HD12 . LEU A 1 276 ? 6.48684   -28.73215 -21.51377 1.000 41.03713  ? 256 LEU A HD12 1 
ATOM   3906 H  HD13 . LEU A 1 276 ? 7.83486   -28.84475 -22.34664 1.000 41.03713  ? 256 LEU A HD13 1 
ATOM   3907 H  HD21 . LEU A 1 276 ? 7.14680   -28.62401 -24.95168 1.000 41.53094  ? 256 LEU A HD21 1 
ATOM   3908 H  HD22 . LEU A 1 276 ? 7.59597   -30.13612 -24.76390 1.000 41.53094  ? 256 LEU A HD22 1 
ATOM   3909 H  HD23 . LEU A 1 276 ? 6.19374   -29.80106 -25.43100 1.000 41.53094  ? 256 LEU A HD23 1 
ATOM   3910 N  N    . GLN A 1 277 ? 5.74157   -34.04560 -22.36433 1.000 33.39985  ? 257 GLN A N    1 
ATOM   3911 C  CA   . GLN A 1 277 ? 6.29741   -35.27082 -21.82550 1.000 42.10698  ? 257 GLN A CA   1 
ATOM   3912 C  C    . GLN A 1 277 ? 6.34736   -36.37252 -22.86711 1.000 45.76181  ? 257 GLN A C    1 
ATOM   3913 O  O    . GLN A 1 277 ? 7.25622   -37.20703 -22.83347 1.000 50.00505  ? 257 GLN A O    1 
ATOM   3914 C  CB   . GLN A 1 277 ? 5.47673   -35.71439 -20.62457 1.000 41.21273  ? 257 GLN A CB   1 
ATOM   3915 C  CG   . GLN A 1 277 ? 6.34382   -36.18240 -19.47288 1.000 53.45228  ? 257 GLN A CG   1 
ATOM   3916 C  CD   . GLN A 1 277 ? 5.59050   -36.17424 -18.18096 1.000 47.88314  ? 257 GLN A CD   1 
ATOM   3917 O  OE1  . GLN A 1 277 ? 5.98288   -35.50479 -17.23477 1.000 49.04662  ? 257 GLN A OE1  1 
ATOM   3918 N  NE2  . GLN A 1 277 ? 4.46883   -36.88634 -18.14918 1.000 52.29955  ? 257 GLN A NE2  1 
ATOM   3919 H  H    . GLN A 1 277 ? 4.96969   -33.82782 -22.05390 1.000 40.10358  ? 257 GLN A H    1 
ATOM   3920 H  HA   . GLN A 1 277 ? 7.20648   -35.10366 -21.53131 1.000 50.55214  ? 257 GLN A HA   1 
ATOM   3921 H  HB2  . GLN A 1 277 ? 4.93997   -34.96832 -20.31446 1.000 49.47903  ? 257 GLN A HB2  1 
ATOM   3922 H  HB3  . GLN A 1 277 ? 4.90179   -36.44996 -20.88780 1.000 49.47903  ? 257 GLN A HB3  1 
ATOM   3923 H  HG2  . GLN A 1 277 ? 6.64457   -37.08836 -19.64514 1.000 64.16649  ? 257 GLN A HG2  1 
ATOM   3924 H  HG3  . GLN A 1 277 ? 7.10724   -35.59051 -19.38481 1.000 64.16649  ? 257 GLN A HG3  1 
ATOM   3925 H  HE21 . GLN A 1 277 ? 4.21385   -37.31839 -18.84770 1.000 62.78322  ? 257 GLN A HE21 1 
ATOM   3926 H  HE22 . GLN A 1 277 ? 3.99797   -36.91509 -17.43011 1.000 62.78322  ? 257 GLN A HE22 1 
ATOM   3927 N  N    . ARG A 1 278 ? 5.41055   -36.39555 -23.80449 1.000 40.19996  ? 258 ARG A N    1 
ATOM   3928 C  CA   . ARG A 1 278 ? 5.43813   -37.45340 -24.80208 1.000 40.94788  ? 258 ARG A CA   1 
ATOM   3929 C  C    . ARG A 1 278 ? 6.18025   -37.07427 -26.07535 1.000 47.21015  ? 258 ARG A C    1 
ATOM   3930 O  O    . ARG A 1 278 ? 6.33132   -37.93573 -26.94701 1.000 46.41720  ? 258 ARG A O    1 
ATOM   3931 C  CB   . ARG A 1 278 ? 4.02429   -37.90076 -25.16003 1.000 47.74549  ? 258 ARG A CB   1 
ATOM   3932 C  CG   . ARG A 1 278 ? 3.16122   -36.85080 -25.81557 1.000 59.70383  ? 258 ARG A CG   1 
ATOM   3933 C  CD   . ARG A 1 278 ? 1.71021   -37.31889 -25.82045 1.000 62.88507  ? 258 ARG A CD   1 
ATOM   3934 N  NE   . ARG A 1 278 ? 0.84849   -36.63921 -26.78393 1.000 72.81765  ? 258 ARG A NE   1 
ATOM   3935 C  CZ   . ARG A 1 278 ? 1.09596   -36.47173 -28.07633 1.000 69.98974  ? 258 ARG A CZ   1 
ATOM   3936 N  NH1  . ARG A 1 278 ? 2.15643   -37.00777 -28.65719 1.000 70.55659  ? 258 ARG A NH1  1 
ATOM   3937 N  NH2  . ARG A 1 278 ? 0.24148   -35.76135 -28.81113 1.000 60.26664  ? 258 ARG A NH2  1 
ATOM   3938 H  H    . ARG A 1 278 ? 4.76934   -35.82753 -23.88070 1.000 48.26371  ? 258 ARG A H    1 
ATOM   3939 H  HA   . ARG A 1 278 ? 5.89799   -38.21045 -24.40673 1.000 49.16122  ? 258 ARG A HA   1 
ATOM   3940 H  HB2  . ARG A 1 278 ? 4.08674   -38.64885 -25.77433 1.000 57.31836  ? 258 ARG A HB2  1 
ATOM   3941 H  HB3  . ARG A 1 278 ? 3.57567   -38.17687 -24.34553 1.000 57.31836  ? 258 ARG A HB3  1 
ATOM   3942 H  HG2  . ARG A 1 278 ? 3.22084   -36.01912 -25.31995 1.000 71.66835  ? 258 ARG A HG2  1 
ATOM   3943 H  HG3  . ARG A 1 278 ? 3.44929   -36.71260 -26.73144 1.000 71.66835  ? 258 ARG A HG3  1 
ATOM   3944 H  HD2  . ARG A 1 278 ? 1.69255   -38.26541 -26.03181 1.000 75.48585  ? 258 ARG A HD2  1 
ATOM   3945 H  HD3  . ARG A 1 278 ? 1.33513   -37.16883 -24.93857 1.000 75.48585  ? 258 ARG A HD3  1 
ATOM   3946 H  HE   . ARG A 1 278 ? 0.10962   -36.31656 -26.48465 1.000 87.40495  ? 258 ARG A HE   1 
ATOM   3947 H  HH11 . ARG A 1 278 ? 2.70741   -37.47946 -28.19510 1.000 84.69167  ? 258 ARG A HH11 1 
ATOM   3948 H  HH12 . ARG A 1 278 ? 2.29500   -36.88462 -29.49698 1.000 84.69167  ? 258 ARG A HH12 1 
ATOM   3949 H  HH21 . ARG A 1 278 ? -0.45820  -35.41929 -28.44639 1.000 72.34373  ? 258 ARG A HH21 1 
ATOM   3950 H  HH22 . ARG A 1 278 ? 0.38955   -35.64482 -29.65024 1.000 72.34373  ? 258 ARG A HH22 1 
ATOM   3951 N  N    . ASP A 1 279 ? 6.64360   -35.83054 -26.21096 1.000 40.43731  ? 259 ASP A N    1 
ATOM   3952 C  CA   . ASP A 1 279 ? 7.35850   -35.40155 -27.41621 1.000 37.83186  ? 259 ASP A CA   1 
ATOM   3953 C  C    . ASP A 1 279 ? 8.42165   -34.36865 -27.06817 1.000 38.02116  ? 259 ASP A C    1 
ATOM   3954 O  O    . ASP A 1 279 ? 8.16301   -33.15505 -27.07216 1.000 33.60699  ? 259 ASP A O    1 
ATOM   3955 C  CB   . ASP A 1 279 ? 6.39195   -34.83830 -28.45320 1.000 37.41264  ? 259 ASP A CB   1 
ATOM   3956 C  CG   . ASP A 1 279 ? 7.03709   -34.62761 -29.78850 1.000 43.53750  ? 259 ASP A CG   1 
ATOM   3957 O  OD1  . ASP A 1 279 ? 8.27771   -34.73577 -29.86769 1.000 41.84719  ? 259 ASP A OD1  1 
ATOM   3958 O  OD2  . ASP A 1 279 ? 6.31403   -34.27823 -30.74153 1.000 44.77135  ? 259 ASP A OD2  1 
ATOM   3959 H  H    . ASP A 1 279 ? 6.55670   -35.21416 -25.61755 1.000 48.54853  ? 259 ASP A H    1 
ATOM   3960 H  HA   . ASP A 1 279 ? 7.82243   -36.17040 -27.78300 1.000 45.42199  ? 259 ASP A HA   1 
ATOM   3961 H  HB2  . ASP A 1 279 ? 5.65581   -35.45909 -28.56984 1.000 44.91893  ? 259 ASP A HB2  1 
ATOM   3962 H  HB3  . ASP A 1 279 ? 6.05797   -33.98224 -28.14251 1.000 44.91893  ? 259 ASP A HB3  1 
ATOM   3963 N  N    . PRO A 1 280 ? 9.65273   -34.81407 -26.80988 1.000 42.32656  ? 260 PRO A N    1 
ATOM   3964 C  CA   . PRO A 1 280 ? 10.70886  -33.87126 -26.40926 1.000 43.19261  ? 260 PRO A CA   1 
ATOM   3965 C  C    . PRO A 1 280 ? 11.13936  -32.92175 -27.50879 1.000 35.92560  ? 260 PRO A C    1 
ATOM   3966 O  O    . PRO A 1 280 ? 11.78399  -31.90728 -27.20430 1.000 36.32251  ? 260 PRO A O    1 
ATOM   3967 C  CB   . PRO A 1 280 ? 11.87299  -34.79526 -26.00510 1.000 61.56075  ? 260 PRO A CB   1 
ATOM   3968 C  CG   . PRO A 1 280 ? 11.24261  -36.14513 -25.75340 1.000 62.86141  ? 260 PRO A CG   1 
ATOM   3969 C  CD   . PRO A 1 280 ? 10.09566  -36.22221 -26.71957 1.000 48.62246  ? 260 PRO A CD   1 
ATOM   3970 H  HA   . PRO A 1 280 ? 10.41149  -33.35920 -25.64098 1.000 51.85489  ? 260 PRO A HA   1 
ATOM   3971 H  HB2  . PRO A 1 280 ? 12.51945  -34.84448 -26.72660 1.000 73.89666  ? 260 PRO A HB2  1 
ATOM   3972 H  HB3  . PRO A 1 280 ? 12.29783  -34.45662 -25.20152 1.000 73.89666  ? 260 PRO A HB3  1 
ATOM   3973 H  HG2  . PRO A 1 280 ? 11.88801  -36.84883 -25.92415 1.000 75.45746  ? 260 PRO A HG2  1 
ATOM   3974 H  HG3  . PRO A 1 280 ? 10.92862  -36.19812 -24.83716 1.000 75.45746  ? 260 PRO A HG3  1 
ATOM   3975 H  HD2  . PRO A 1 280 ? 10.39041  -36.55002 -27.58361 1.000 58.37071  ? 260 PRO A HD2  1 
ATOM   3976 H  HD3  . PRO A 1 280 ? 9.38750   -36.78792 -26.37407 1.000 58.37071  ? 260 PRO A HD3  1 
ATOM   3977 N  N    . SER A 1 281 ? 10.83431  -33.21842 -28.77193 1.000 34.92239  ? 261 SER A N    1 
ATOM   3978 C  CA   . SER A 1 281 ? 11.16886  -32.29646 -29.83954 1.000 35.68851  ? 261 SER A CA   1 
ATOM   3979 C  C    . SER A 1 281 ? 10.35445  -31.01536 -29.76176 1.000 31.01320  ? 261 SER A C    1 
ATOM   3980 O  O    . SER A 1 281 ? 10.68346  -30.03788 -30.45856 1.000 33.92073  ? 261 SER A O    1 
ATOM   3981 C  CB   . SER A 1 281 ? 10.97742  -32.98050 -31.20809 1.000 42.63298  ? 261 SER A CB   1 
ATOM   3982 O  OG   . SER A 1 281 ? 9.62426   -33.02310 -31.61012 1.000 41.24775  ? 261 SER A OG   1 
ATOM   3983 H  H    . SER A 1 281 ? 10.43926  -33.93844 -29.02709 1.000 41.93063  ? 261 SER A H    1 
ATOM   3984 H  HA   . SER A 1 281 ? 12.10571  -32.05379 -29.77370 1.000 42.84997  ? 261 SER A HA   1 
ATOM   3985 H  HB2  . SER A 1 281 ? 11.48148  -32.48619 -31.87328 1.000 51.18334  ? 261 SER A HB2  1 
ATOM   3986 H  HB3  . SER A 1 281 ? 11.31012  -33.88966 -31.14781 1.000 51.18334  ? 261 SER A HB3  1 
ATOM   3987 H  HG   . SER A 1 281 ? 9.16320   -33.41299 -31.02617 1.000 49.52106  ? 261 SER A HG   1 
ATOM   3988 N  N    . LEU A 1 282 ? 9.31447   -30.98045 -28.91407 1.000 30.56670  ? 262 LEU A N    1 
ATOM   3989 C  CA   . LEU A 1 282 ? 8.53345   -29.75543 -28.70936 1.000 30.99752  ? 262 LEU A CA   1 
ATOM   3990 C  C    . LEU A 1 282 ? 9.14871   -28.80561 -27.68186 1.000 26.59635  ? 262 LEU A C    1 
ATOM   3991 O  O    . LEU A 1 282 ? 8.63512   -27.70327 -27.47676 1.000 25.43091  ? 262 LEU A O    1 
ATOM   3992 C  CB   . LEU A 1 282 ? 7.11585   -30.11140 -28.26219 1.000 28.67396  ? 262 LEU A CB   1 
ATOM   3993 C  CG   . LEU A 1 282 ? 6.21930   -30.88345 -29.21982 1.000 34.25194  ? 262 LEU A CG   1 
ATOM   3994 C  CD1  . LEU A 1 282 ? 4.84409   -31.07833 -28.60966 1.000 35.60606  ? 262 LEU A CD1  1 
ATOM   3995 C  CD2  . LEU A 1 282 ? 6.10463   -30.14139 -30.57028 1.000 37.18099  ? 262 LEU A CD2  1 
ATOM   3996 H  H    . LEU A 1 282 ? 9.04461   -31.65165 -28.44903 1.000 36.70380  ? 262 LEU A H    1 
ATOM   3997 H  HA   . LEU A 1 282 ? 8.48555   -29.28676 -29.55727 1.000 37.22079  ? 262 LEU A HA   1 
ATOM   3998 H  HB2  . LEU A 1 282 ? 7.19000   -30.65049 -27.45921 1.000 34.43251  ? 262 LEU A HB2  1 
ATOM   3999 H  HB3  . LEU A 1 282 ? 6.65567   -29.28106 -28.06301 1.000 34.43251  ? 262 LEU A HB3  1 
ATOM   4000 H  HG   . LEU A 1 282 ? 6.60886   -31.75625 -29.38521 1.000 41.12609  ? 262 LEU A HG   1 
ATOM   4001 H  HD11 . LEU A 1 282 ? 4.29347   -31.58465 -29.22720 1.000 42.75104  ? 262 LEU A HD11 1 
ATOM   4002 H  HD12 . LEU A 1 282 ? 4.93505   -31.56260 -27.77413 1.000 42.75104  ? 262 LEU A HD12 1 
ATOM   4003 H  HD13 . LEU A 1 282 ? 4.44493   -30.20943 -28.44660 1.000 42.75104  ? 262 LEU A HD13 1 
ATOM   4004 H  HD21 . LEU A 1 282 ? 5.39845   -30.54906 -31.09566 1.000 44.64095  ? 262 LEU A HD21 1 
ATOM   4005 H  HD22 . LEU A 1 282 ? 5.89550   -29.20933 -30.40170 1.000 44.64095  ? 262 LEU A HD22 1 
ATOM   4006 H  HD23 . LEU A 1 282 ? 6.94963   -30.21081 -31.04151 1.000 44.64095  ? 262 LEU A HD23 1 
ATOM   4007 N  N    . LEU A 1 283 ? 10.23368  -29.18717 -27.02312 1.000 26.10329  ? 263 LEU A N    1 
ATOM   4008 C  CA   . LEU A 1 283 ? 10.78783  -28.33734 -25.97957 1.000 25.89236  ? 263 LEU A CA   1 
ATOM   4009 C  C    . LEU A 1 283 ? 11.25707  -26.98162 -26.49107 1.000 23.82802  ? 263 LEU A C    1 
ATOM   4010 O  O    . LEU A 1 283 ? 10.97641  -25.97773 -25.81264 1.000 23.31062  ? 263 LEU A O    1 
ATOM   4011 C  CB   . LEU A 1 283 ? 11.91847  -29.11840 -25.28755 1.000 27.13346  ? 263 LEU A CB   1 
ATOM   4012 C  CG   . LEU A 1 283 ? 12.53280  -28.41748 -24.08042 1.000 30.85571  ? 263 LEU A CG   1 
ATOM   4013 C  CD1  . LEU A 1 283 ? 11.49354  -28.20651 -22.97396 1.000 28.70917  ? 263 LEU A CD1  1 
ATOM   4014 C  CD2  . LEU A 1 283 ? 13.71263  -29.24288 -23.55344 1.000 35.24563  ? 263 LEU A CD2  1 
ATOM   4015 H  H    . LEU A 1 283 ? 10.66206  -29.92067 -27.15753 1.000 31.34771  ? 263 LEU A H    1 
ATOM   4016 H  HA   . LEU A 1 283 ? 10.09887  -28.14449 -25.32455 1.000 31.09460  ? 263 LEU A HA   1 
ATOM   4017 H  HB2  . LEU A 1 283 ? 11.56324  -29.96808 -24.98300 1.000 32.58392  ? 263 LEU A HB2  1 
ATOM   4018 H  HB3  . LEU A 1 283 ? 12.62812  -29.26728 -25.93185 1.000 32.58392  ? 263 LEU A HB3  1 
ATOM   4019 H  HG   . LEU A 1 283 ? 12.85219  -27.54206 -24.34971 1.000 37.05061  ? 263 LEU A HG   1 
ATOM   4020 H  HD11 . LEU A 1 283 ? 11.93988  -27.86895 -22.18167 1.000 34.47477  ? 263 LEU A HD11 1 
ATOM   4021 H  HD12 . LEU A 1 283 ? 10.83255  -27.56573 -23.27957 1.000 34.47477  ? 263 LEU A HD12 1 
ATOM   4022 H  HD13 . LEU A 1 283 ? 11.06575  -29.05443 -22.77668 1.000 34.47477  ? 263 LEU A HD13 1 
ATOM   4023 H  HD21 . LEU A 1 283 ? 14.08647  -28.79895 -22.77622 1.000 42.31852  ? 263 LEU A HD21 1 
ATOM   4024 H  HD22 . LEU A 1 283 ? 13.39574  -30.12651 -23.30913 1.000 42.31852  ? 263 LEU A HD22 1 
ATOM   4025 H  HD23 . LEU A 1 283 ? 14.38469  -29.31319 -24.24935 1.000 42.31852  ? 263 LEU A HD23 1 
ATOM   4026 N  N    . PRO A 1 284 ? 11.90765  -26.84826 -27.65840 1.000 25.29523  ? 264 PRO A N    1 
ATOM   4027 C  CA   . PRO A 1 284 ? 12.29647  -25.49016 -28.08823 1.000 25.36076  ? 264 PRO A CA   1 
ATOM   4028 C  C    . PRO A 1 284 ? 11.12962  -24.51778 -28.19177 1.000 23.53929  ? 264 PRO A C    1 
ATOM   4029 O  O    . PRO A 1 284 ? 11.21333  -23.38258 -27.67526 1.000 23.45105  ? 264 PRO A O    1 
ATOM   4030 C  CB   . PRO A 1 284 ? 12.97577  -25.71093 -29.44431 1.000 25.05878  ? 264 PRO A CB   1 
ATOM   4031 C  CG   . PRO A 1 284 ? 13.55153  -27.12208 -29.33227 1.000 29.35151  ? 264 PRO A CG   1 
ATOM   4032 C  CD   . PRO A 1 284 ? 12.49393  -27.89134 -28.52296 1.000 29.31465  ? 264 PRO A CD   1 
ATOM   4033 H  HA   . PRO A 1 284 ? 12.94801  -25.14513 -27.45787 1.000 30.45668  ? 264 PRO A HA   1 
ATOM   4034 H  HB2  . PRO A 1 284 ? 12.32368  -25.65239 -30.16002 1.000 30.09430  ? 264 PRO A HB2  1 
ATOM   4035 H  HB3  . PRO A 1 284 ? 13.67673  -25.05425 -29.57961 1.000 30.09430  ? 264 PRO A HB3  1 
ATOM   4036 H  HG2  . PRO A 1 284 ? 13.66635  -27.50787 -30.21481 1.000 35.24557  ? 264 PRO A HG2  1 
ATOM   4037 H  HG3  . PRO A 1 284 ? 14.40204  -27.10064 -28.86635 1.000 35.24557  ? 264 PRO A HG3  1 
ATOM   4038 H  HD2  . PRO A 1 284 ? 11.82137  -28.27352 -29.10819 1.000 35.20134  ? 264 PRO A HD2  1 
ATOM   4039 H  HD3  . PRO A 1 284 ? 12.90634  -28.58974 -27.99093 1.000 35.20134  ? 264 PRO A HD3  1 
ATOM   4040 N  N    . GLY A 1 285 ? 10.02290  -24.94698 -28.80258 1.000 25.54869  ? 265 GLY A N    1 
ATOM   4041 C  CA   . GLY A 1 285 ? 8.85452   -24.08169 -28.86072 1.000 25.13650  ? 265 GLY A CA   1 
ATOM   4042 C  C    . GLY A 1 285 ? 8.21862   -23.82425 -27.52109 1.000 22.85255  ? 265 GLY A C    1 
ATOM   4043 O  O    . GLY A 1 285 ? 7.70839   -22.70836 -27.25721 1.000 21.04151  ? 265 GLY A O    1 
ATOM   4044 H  H    . GLY A 1 285 ? 9.92884   -25.71416 -29.17965 1.000 30.68219  ? 265 GLY A H    1 
ATOM   4045 H  HA2  . GLY A 1 285 ? 9.11443   -23.22669 -29.23798 1.000 30.18756  ? 265 GLY A HA2  1 
ATOM   4046 H  HA3  . GLY A 1 285 ? 8.18812   -24.49068 -29.43478 1.000 30.18756  ? 265 GLY A HA3  1 
ATOM   4047 N  N    . ALA A 1 286 ? 8.29044   -24.79969 -26.61982 1.000 22.24134  ? 266 ALA A N    1 
ATOM   4048 C  CA   . ALA A 1 286 ? 7.77487   -24.56420 -25.28132 1.000 19.30823  ? 266 ALA A CA   1 
ATOM   4049 C  C    . ALA A 1 286 ? 8.54645   -23.47347 -24.58313 1.000 21.22578  ? 266 ALA A C    1 
ATOM   4050 O  O    . ALA A 1 286 ? 7.94682   -22.64809 -23.88014 1.000 19.46132  ? 266 ALA A O    1 
ATOM   4051 C  CB   . ALA A 1 286 ? 7.83378   -25.84215 -24.44695 1.000 23.06900  ? 266 ALA A CB   1 
ATOM   4052 H  H    . ALA A 1 286 ? 8.62262   -25.58127 -26.75543 1.000 26.71336  ? 266 ALA A H    1 
ATOM   4053 H  HA   . ALA A 1 286 ? 6.84681   -24.29376 -25.36175 1.000 23.19364  ? 266 ALA A HA   1 
ATOM   4054 H  HB1  . ALA A 1 286 ? 7.52494   -25.64712 -23.54835 1.000 27.70656  ? 266 ALA A HB1  1 
ATOM   4055 H  HB2  . ALA A 1 286 ? 7.26308   -26.51215 -24.85475 1.000 27.70656  ? 266 ALA A HB2  1 
ATOM   4056 H  HB3  . ALA A 1 286 ? 8.74988   -26.15988 -24.42019 1.000 27.70656  ? 266 ALA A HB3  1 
ATOM   4057 N  N    . ILE A 1 287 ? 9.88539   -23.49796 -24.70259 1.000 21.08950  ? 267 ILE A N    1 
ATOM   4058 C  CA   . ILE A 1 287 ? 10.68942  -22.49574 -24.02331 1.000 20.26502  ? 267 ILE A CA   1 
ATOM   4059 C  C    . ILE A 1 287 ? 10.34698  -21.10909 -24.55682 1.000 20.56219  ? 267 ILE A C    1 
ATOM   4060 O  O    . ILE A 1 287 ? 10.26577  -20.14511 -23.79852 1.000 19.23780  ? 267 ILE A O    1 
ATOM   4061 C  CB   . ILE A 1 287 ? 12.18503  -22.82883 -24.16236 1.000 22.04268  ? 267 ILE A CB   1 
ATOM   4062 C  CG1  . ILE A 1 287 ? 12.55275  -24.11410 -23.39330 1.000 24.90674  ? 267 ILE A CG1  1 
ATOM   4063 C  CG2  . ILE A 1 287 ? 13.05601  -21.63346 -23.76320 1.000 26.53452  ? 267 ILE A CG2  1 
ATOM   4064 C  CD1  . ILE A 1 287 ? 12.07852  -24.27625 -22.07585 1.000 26.86865  ? 267 ILE A CD1  1 
ATOM   4065 H  H    . ILE A 1 287 ? 10.33159  -24.07281 -25.16090 1.000 25.33116  ? 267 ILE A H    1 
ATOM   4066 H  HA   . ILE A 1 287 ? 10.48144  -22.50598 -23.07593 1.000 24.34179  ? 267 ILE A HA   1 
ATOM   4067 H  HB   . ILE A 1 287 ? 12.36360  -23.00935 -25.09854 1.000 26.47498  ? 267 ILE A HB   1 
ATOM   4068 H  HG12 . ILE A 1 287 ? 12.21202  -24.86650 -23.90193 1.000 29.91185  ? 267 ILE A HG12 1 
ATOM   4069 H  HG13 . ILE A 1 287 ? 13.52049  -24.15814 -23.34375 1.000 29.91185  ? 267 ILE A HG13 1 
ATOM   4070 H  HG21 . ILE A 1 287 ? 13.96819  -21.93673 -23.63338 1.000 31.86518  ? 267 ILE A HG21 1 
ATOM   4071 H  HG22 . ILE A 1 287 ? 13.02540  -20.97028 -24.47042 1.000 31.86518  ? 267 ILE A HG22 1 
ATOM   4072 H  HG23 . ILE A 1 287 ? 12.71308  -21.25411 -22.93895 1.000 31.86518  ? 267 ILE A HG23 1 
ATOM   4073 H  HD11 . ILE A 1 287 ? 12.58130  -24.98460 -21.64417 1.000 32.26614  ? 267 ILE A HD11 1 
ATOM   4074 H  HD12 . ILE A 1 287 ? 12.19812  -23.44382 -21.59246 1.000 32.26614  ? 267 ILE A HD12 1 
ATOM   4075 H  HD13 . ILE A 1 287 ? 11.13740  -24.50931 -22.10542 1.000 32.26614  ? 267 ILE A HD13 1 
ATOM   4076 N  N    . GLU A 1 288 ? 10.12092  -20.99574 -25.86552 1.000 18.35138  ? 268 GLU A N    1 
ATOM   4077 C  CA   . GLU A 1 288 ? 9.76400   -19.69000 -26.43921 1.000 20.38360  ? 268 GLU A CA   1 
ATOM   4078 C  C    . GLU A 1 288 ? 8.40183   -19.21432 -25.93353 1.000 19.60026  ? 268 GLU A C    1 
ATOM   4079 O  O    . GLU A 1 288 ? 8.23387   -18.01942 -25.65216 1.000 18.51850  ? 268 GLU A O    1 
ATOM   4080 C  CB   . GLU A 1 288 ? 9.76472   -19.72366 -27.96237 1.000 20.59088  ? 268 GLU A CB   1 
ATOM   4081 C  CG   . GLU A 1 288 ? 11.10213  -20.03338 -28.55154 1.000 21.07805  ? 268 GLU A CG   1 
ATOM   4082 C  CD   . GLU A 1 288 ? 12.21155  -19.11917 -28.04102 1.000 22.08019  ? 268 GLU A CD   1 
ATOM   4083 O  OE1  . GLU A 1 288 ? 12.05991  -17.87717 -28.16502 1.000 24.36572  ? 268 GLU A OE1  1 
ATOM   4084 O  OE2  . GLU A 1 288 ? 13.20813  -19.63580 -27.43639 1.000 23.64377  ? 268 GLU A OE2  1 
ATOM   4085 H  H    . GLU A 1 288 ? 10.16531  -21.64042 -26.43299 1.000 22.04541  ? 268 GLU A H    1 
ATOM   4086 H  HA   . GLU A 1 288 ? 10.44518  -19.05751 -26.16197 1.000 24.48408  ? 268 GLU A HA   1 
ATOM   4087 H  HB2  . GLU A 1 288 ? 9.14349   -20.40645 -28.26030 1.000 24.73282  ? 268 GLU A HB2  1 
ATOM   4088 H  HB3  . GLU A 1 288 ? 9.48767   -18.85539 -28.29442 1.000 24.73282  ? 268 GLU A HB3  1 
ATOM   4089 H  HG2  . GLU A 1 288 ? 11.34101  -20.94609 -28.32613 1.000 25.31742  ? 268 GLU A HG2  1 
ATOM   4090 H  HG3  . GLU A 1 288 ? 11.05221  -19.93178 -29.51491 1.000 25.31742  ? 268 GLU A HG3  1 
ATOM   4091 N  N    . GLU A 1 289 ? 7.44016   -20.14449 -25.74820 1.000 18.25770  ? 269 GLU A N    1 
ATOM   4092 C  CA   . GLU A 1 289 ? 6.15728   -19.72013 -25.19389 1.000 19.45160  ? 269 GLU A CA   1 
ATOM   4093 C  C    . GLU A 1 289 ? 6.25551   -19.37342 -23.71267 1.000 20.57142  ? 269 GLU A C    1 
ATOM   4094 O  O    . GLU A 1 289 ? 5.56015   -18.46595 -23.24703 1.000 19.84255  ? 269 GLU A O    1 
ATOM   4095 C  CB   . GLU A 1 289 ? 5.09197   -20.78868 -25.48142 1.000 21.28404  ? 269 GLU A CB   1 
ATOM   4096 C  CG   . GLU A 1 289 ? 3.65180   -20.40549 -25.04856 1.000 21.42245  ? 269 GLU A CG   1 
ATOM   4097 C  CD   . GLU A 1 289 ? 2.95360   -19.37969 -25.93241 1.000 21.19548  ? 269 GLU A CD   1 
ATOM   4098 O  OE1  . GLU A 1 289 ? 3.66619   -18.56574 -26.59244 1.000 22.84412  ? 269 GLU A OE1  1 
ATOM   4099 O  OE2  . GLU A 1 289 ? 1.68143   -19.37266 -25.96535 1.000 21.21105  ? 269 GLU A OE2  1 
ATOM   4100 H  H    . GLU A 1 289 ? 7.51068   -20.98233 -25.92888 1.000 21.93301  ? 269 GLU A H    1 
ATOM   4101 H  HA   . GLU A 1 289 ? 5.86658   -18.90705 -25.63580 1.000 23.36569  ? 269 GLU A HA   1 
ATOM   4102 H  HB2  . GLU A 1 289 ? 5.07447   -20.95650 -26.43663 1.000 25.56461  ? 269 GLU A HB2  1 
ATOM   4103 H  HB3  . GLU A 1 289 ? 5.33326   -21.59933 -25.00651 1.000 25.56461  ? 269 GLU A HB3  1 
ATOM   4104 H  HG2  . GLU A 1 289 ? 3.10741   -21.20832 -25.05320 1.000 25.73071  ? 269 GLU A HG2  1 
ATOM   4105 H  HG3  . GLU A 1 289 ? 3.69007   -20.03578 -24.15260 1.000 25.73071  ? 269 GLU A HG3  1 
ATOM   4106 N  N    . MET A 1 290 ? 7.14753   -20.02049 -22.96279 1.000 18.10568  ? 270 MET A N    1 
ATOM   4107 C  CA   . MET A 1 290 ? 7.36563   -19.65259 -21.57432 1.000 17.94521  ? 270 MET A CA   1 
ATOM   4108 C  C    . MET A 1 290 ? 7.92840   -18.22755 -21.50507 1.000 16.68499  ? 270 MET A C    1 
ATOM   4109 O  O    . MET A 1 290 ? 7.49317   -17.42397 -20.66303 1.000 17.23472  ? 270 MET A O    1 
ATOM   4110 C  CB   . MET A 1 290 ? 8.34196   -20.66849 -20.97457 1.000 18.74811  ? 270 MET A CB   1 
ATOM   4111 C  CG   . MET A 1 290 ? 7.68364   -22.01945 -20.76865 1.000 17.43430  ? 270 MET A CG   1 
ATOM   4112 S  SD   . MET A 1 290 ? 8.96343   -23.24072 -20.40462 1.000 29.06437  ? 270 MET A SD   1 
ATOM   4113 C  CE   . MET A 1 290 ? 9.52684   -22.66058 -18.99858 1.000 24.15445  ? 270 MET A CE   1 
ATOM   4114 H  H    . MET A 1 290 ? 7.63588   -20.67338 -23.23636 1.000 21.75058  ? 270 MET A H    1 
ATOM   4115 H  HA   . MET A 1 290 ? 6.54165   -19.68261 -21.06339 1.000 21.55802  ? 270 MET A HA   1 
ATOM   4116 H  HB2  . MET A 1 290 ? 9.09404   -20.78369 -21.57623 1.000 22.52149  ? 270 MET A HB2  1 
ATOM   4117 H  HB3  . MET A 1 290 ? 8.65193   -20.34540 -20.11409 1.000 22.52149  ? 270 MET A HB3  1 
ATOM   4118 H  HG2  . MET A 1 290 ? 7.06566   -21.97638 -20.02224 1.000 20.94493  ? 270 MET A HG2  1 
ATOM   4119 H  HG3  . MET A 1 290 ? 7.21291   -22.28469 -21.57423 1.000 20.94493  ? 270 MET A HG3  1 
ATOM   4120 H  HE1  . MET A 1 290 ? 10.24212  -23.23520 -18.68379 1.000 29.00910  ? 270 MET A HE1  1 
ATOM   4121 H  HE2  . MET A 1 290 ? 9.86262   -21.76157 -19.13975 1.000 29.00910  ? 270 MET A HE2  1 
ATOM   4122 H  HE3  . MET A 1 290 ? 8.80486   -22.64612 -18.35094 1.000 29.00910  ? 270 MET A HE3  1 
ATOM   4123 N  N    . LEU A 1 291 ? 8.85388   -17.89473 -22.43380 1.000 18.01960  ? 271 LEU A N    1 
ATOM   4124 C  CA   . LEU A 1 291 ? 9.43977   -16.56334 -22.51044 1.000 15.30156  ? 271 LEU A CA   1 
ATOM   4125 C  C    . LEU A 1 291 ? 8.40127   -15.51676 -22.89009 1.000 16.10965  ? 271 LEU A C    1 
ATOM   4126 O  O    . LEU A 1 291 ? 8.32609   -14.46918 -22.25388 1.000 16.62701  ? 271 LEU A O    1 
ATOM   4127 C  CB   . LEU A 1 291 ? 10.58446  -16.54356 -23.51576 1.000 16.67928  ? 271 LEU A CB   1 
ATOM   4128 C  CG   . LEU A 1 291 ? 11.87833  -17.22036 -23.04477 1.000 17.47016  ? 271 LEU A CG   1 
ATOM   4129 C  CD1  . LEU A 1 291 ? 12.77513  -17.59976 -24.18803 1.000 17.53718  ? 271 LEU A CD1  1 
ATOM   4130 C  CD2  . LEU A 1 291 ? 12.59977  -16.28821 -22.04236 1.000 19.40247  ? 271 LEU A CD2  1 
ATOM   4131 H  H    . LEU A 1 291 ? 9.15434   -18.43539 -23.03130 1.000 21.64728  ? 271 LEU A H    1 
ATOM   4132 H  HA   . LEU A 1 291 ? 9.79392   -16.34186 -21.63499 1.000 18.38563  ? 271 LEU A HA   1 
ATOM   4133 H  HB2  . LEU A 1 291 ? 10.29301  -17.00118 -24.31984 1.000 20.03890  ? 271 LEU A HB2  1 
ATOM   4134 H  HB3  . LEU A 1 291 ? 10.79708  -15.61917 -23.71870 1.000 20.03890  ? 271 LEU A HB3  1 
ATOM   4135 H  HG   . LEU A 1 291 ? 11.65667  -18.05388 -22.60091 1.000 20.98796  ? 271 LEU A HG   1 
ATOM   4136 H  HD11 . LEU A 1 291 ? 13.55972  -18.05007 -23.83796 1.000 21.06837  ? 271 LEU A HD11 1 
ATOM   4137 H  HD12 . LEU A 1 291 ? 12.29224  -18.19260 -24.78490 1.000 21.06837  ? 271 LEU A HD12 1 
ATOM   4138 H  HD13 . LEU A 1 291 ? 13.03919  -16.79596 -24.66246 1.000 21.06837  ? 271 LEU A HD13 1 
ATOM   4139 H  HD21 . LEU A 1 291 ? 13.43785  -16.69813 -21.77688 1.000 23.30672  ? 271 LEU A HD21 1 
ATOM   4140 H  HD22 . LEU A 1 291 ? 12.77008  -15.43488 -22.47099 1.000 23.30672  ? 271 LEU A HD22 1 
ATOM   4141 H  HD23 . LEU A 1 291 ? 12.03310  -16.16088 -21.26546 1.000 23.30672  ? 271 LEU A HD23 1 
ATOM   4142 N  N    . ARG A 1 292 ? 7.60621   -15.78335 -23.94844 1.000 16.75217  ? 272 ARG A N    1 
ATOM   4143 C  CA   . ARG A 1 292 ? 6.55579   -14.83358 -24.32581 1.000 17.20616  ? 272 ARG A CA   1 
ATOM   4144 C  C    . ARG A 1 292 ? 5.64728   -14.51177 -23.15262 1.000 17.53478  ? 272 ARG A C    1 
ATOM   4145 O  O    . ARG A 1 292 ? 5.34545   -13.34323 -22.87029 1.000 17.36786  ? 272 ARG A O    1 
ATOM   4146 C  CB   . ARG A 1 292 ? 5.71640   -15.40260 -25.47899 1.000 16.18275  ? 272 ARG A CB   1 
ATOM   4147 C  CG   . ARG A 1 292 ? 4.67463   -14.41665 -25.92386 1.000 16.46443  ? 272 ARG A CG   1 
ATOM   4148 C  CD   . ARG A 1 292 ? 3.66593   -14.92909 -27.00089 1.000 18.53313  ? 272 ARG A CD   1 
ATOM   4149 N  NE   . ARG A 1 292 ? 2.72244   -15.91556 -26.47684 1.000 20.14459  ? 272 ARG A NE   1 
ATOM   4150 C  CZ   . ARG A 1 292 ? 1.56834   -15.63364 -25.88520 1.000 20.80940  ? 272 ARG A CZ   1 
ATOM   4151 N  NH1  . ARG A 1 292 ? 1.13419   -14.38417 -25.74613 1.000 19.52875  ? 272 ARG A NH1  1 
ATOM   4152 N  NH2  . ARG A 1 292 ? 0.82249   -16.62768 -25.41281 1.000 19.99609  ? 272 ARG A NH2  1 
ATOM   4153 H  H    . ARG A 1 292 ? 7.65803   -16.48489 -24.44317 1.000 20.12637  ? 272 ARG A H    1 
ATOM   4154 H  HA   . ARG A 1 292 ? 6.98463   -14.01539 -24.62172 1.000 20.67115  ? 272 ARG A HA   1 
ATOM   4155 H  HB2  . ARG A 1 292 ? 6.29499   -15.59988 -26.23213 1.000 19.44307  ? 272 ARG A HB2  1 
ATOM   4156 H  HB3  . ARG A 1 292 ? 5.26892   -16.21098 -25.18372 1.000 19.44307  ? 272 ARG A HB3  1 
ATOM   4157 H  HG2  . ARG A 1 292 ? 4.15526   -14.15202 -25.14854 1.000 19.78107  ? 272 ARG A HG2  1 
ATOM   4158 H  HG3  . ARG A 1 292 ? 5.12664   -13.64499 -26.29952 1.000 19.78107  ? 272 ARG A HG3  1 
ATOM   4159 H  HD2  . ARG A 1 292 ? 3.15491   -14.17653 -27.33765 1.000 22.26352  ? 272 ARG A HD2  1 
ATOM   4160 H  HD3  . ARG A 1 292 ? 4.16103   -15.34425 -27.72436 1.000 22.26352  ? 272 ARG A HD3  1 
ATOM   4161 H  HE   . ARG A 1 292 ? 2.93231   -16.74554 -26.55859 1.000 24.19727  ? 272 ARG A HE   1 
ATOM   4162 H  HH11 . ARG A 1 292 ? 1.60562   -13.72948 -26.04401 1.000 23.45826  ? 272 ARG A HH11 1 
ATOM   4163 H  HH12 . ARG A 1 292 ? 0.38204   -14.23096 -25.35832 1.000 23.45826  ? 272 ARG A HH12 1 
ATOM   4164 H  HH21 . ARG A 1 292 ? 1.08974   -17.44120 -25.49254 1.000 24.01907  ? 272 ARG A HH21 1 
ATOM   4165 H  HH22 . ARG A 1 292 ? 0.07278   -16.45716 -25.02751 1.000 24.01907  ? 272 ARG A HH22 1 
ATOM   4166 N  N    . TRP A 1 293 ? 5.17147   -15.55975 -22.47028 1.000 16.96801  ? 273 TRP A N    1 
ATOM   4167 C  CA   . TRP A 1 293 ? 4.16258   -15.41696 -21.43379 1.000 17.79659  ? 273 TRP A CA   1 
ATOM   4168 C  C    . TRP A 1 293 ? 4.69056   -14.65530 -20.22641 1.000 18.33133  ? 273 TRP A C    1 
ATOM   4169 O  O    . TRP A 1 293 ? 3.97663   -13.82023 -19.66279 1.000 18.02231  ? 273 TRP A O    1 
ATOM   4170 C  CB   . TRP A 1 293 ? 3.69276   -16.80966 -21.01048 1.000 19.34755  ? 273 TRP A CB   1 
ATOM   4171 C  CG   . TRP A 1 293 ? 2.53102   -16.79388 -20.09887 1.000 19.75080  ? 273 TRP A CG   1 
ATOM   4172 C  CD1  . TRP A 1 293 ? 2.54561   -16.65504 -18.74874 1.000 20.40665  ? 273 TRP A CD1  1 
ATOM   4173 C  CD2  . TRP A 1 293 ? 1.15742   -16.88252 -20.48682 1.000 20.27563  ? 273 TRP A CD2  1 
ATOM   4174 N  NE1  . TRP A 1 293 ? 1.26378   -16.67065 -18.26108 1.000 22.41457  ? 273 TRP A NE1  1 
ATOM   4175 C  CE2  . TRP A 1 293 ? 0.39033   -16.80424 -19.31174 1.000 22.08492  ? 273 TRP A CE2  1 
ATOM   4176 C  CE3  . TRP A 1 293 ? 0.49316   -17.00671 -21.73053 1.000 19.98879  ? 273 TRP A CE3  1 
ATOM   4177 C  CZ2  . TRP A 1 293 ? -0.98665  -16.83989 -19.32445 1.000 24.71085  ? 273 TRP A CZ2  1 
ATOM   4178 C  CZ3  . TRP A 1 293 ? -0.90823  -17.08120 -21.72486 1.000 23.81516  ? 273 TRP A CZ3  1 
ATOM   4179 C  CH2  . TRP A 1 293 ? -1.61767  -17.01628 -20.52433 1.000 23.48084  ? 273 TRP A CH2  1 
ATOM   4180 H  H    . TRP A 1 293 ? 5.42343   -16.37261 -22.59427 1.000 20.38537  ? 273 TRP A H    1 
ATOM   4181 H  HA   . TRP A 1 293 ? 3.41276   -14.91494 -21.78967 1.000 21.37967  ? 273 TRP A HA   1 
ATOM   4182 H  HB2  . TRP A 1 293 ? 3.44012   -17.30805 -21.80337 1.000 23.24082  ? 273 TRP A HB2  1 
ATOM   4183 H  HB3  . TRP A 1 293 ? 4.42109   -17.25925 -20.55408 1.000 23.24082  ? 273 TRP A HB3  1 
ATOM   4184 H  HD1  . TRP A 1 293 ? 3.31226   -16.56286 -18.23041 1.000 24.51174  ? 273 TRP A HD1  1 
ATOM   4185 H  HE1  . TRP A 1 293 ? 1.04318   -16.60712 -17.43228 1.000 26.92125  ? 273 TRP A HE1  1 
ATOM   4186 H  HE3  . TRP A 1 293 ? 0.97114   -17.03800 -22.52769 1.000 24.01030  ? 273 TRP A HE3  1 
ATOM   4187 H  HZ2  . TRP A 1 293 ? -1.47397  -16.74648 -18.53788 1.000 29.67678  ? 273 TRP A HZ2  1 
ATOM   4188 H  HZ3  . TRP A 1 293 ? -1.36820  -17.17462 -22.52773 1.000 28.60196  ? 273 TRP A HZ3  1 
ATOM   4189 H  HH2  . TRP A 1 293 ? -2.54417  -17.09510 -20.54123 1.000 28.20077  ? 273 TRP A HH2  1 
ATOM   4190 N  N    . THR A 1 294 ? 5.89311   -14.97923 -19.78319 1.000 16.17906  ? 274 THR A N    1 
ATOM   4191 C  CA   . THR A 1 294 ? 6.39279   -14.51364 -18.50163 1.000 16.78950  ? 274 THR A CA   1 
ATOM   4192 C  C    . THR A 1 294 ? 7.04408   -13.14428 -18.58243 1.000 18.38648  ? 274 THR A C    1 
ATOM   4193 O  O    . THR A 1 294 ? 7.01885   -12.41053 -17.58275 1.000 18.64391  ? 274 THR A O    1 
ATOM   4194 C  CB   . THR A 1 294 ? 7.40376   -15.49563 -17.89582 1.000 17.21385  ? 274 THR A CB   1 
ATOM   4195 O  OG1  . THR A 1 294 ? 8.49305   -15.69899 -18.77342 1.000 18.35368  ? 274 THR A OG1  1 
ATOM   4196 C  CG2  . THR A 1 294 ? 6.70856   -16.81522 -17.54556 1.000 19.03903  ? 274 THR A CG2  1 
ATOM   4197 H  H    . THR A 1 294 ? 6.44883   -15.47573 -20.21247 1.000 19.43863  ? 274 THR A H    1 
ATOM   4198 H  HA   . THR A 1 294 ? 5.63390   -14.46674 -17.89931 1.000 20.17116  ? 274 THR A HA   1 
ATOM   4199 H  HB   . THR A 1 294 ? 7.76731   -15.12876 -17.07476 1.000 20.68038  ? 274 THR A HB   1 
ATOM   4200 H  HG1  . THR A 1 294 ? 8.21891   -16.00808 -19.50480 1.000 22.04818  ? 274 THR A HG1  1 
ATOM   4201 H  HG21 . THR A 1 294 ? 7.35535   -17.44874 -17.19739 1.000 22.87059  ? 274 THR A HG21 1 
ATOM   4202 H  HG22 . THR A 1 294 ? 6.02509   -16.66221 -16.87448 1.000 22.87059  ? 274 THR A HG22 1 
ATOM   4203 H  HG23 . THR A 1 294 ? 6.29364   -17.19195 -18.33727 1.000 22.87059  ? 274 THR A HG23 1 
ATOM   4204 N  N    . ALA A 1 295 ? 7.62582   -12.79142 -19.73456 1.000 17.35521  ? 275 ALA A N    1 
ATOM   4205 C  CA   . ALA A 1 295 ? 8.30116   -11.50968 -19.93223 1.000 19.35971  ? 275 ALA A CA   1 
ATOM   4206 C  C    . ALA A 1 295 ? 8.88369   -10.91483 -18.65513 1.000 18.96753  ? 275 ALA A C    1 
ATOM   4207 O  O    . ALA A 1 295 ? 8.41521   -9.86592  -18.13861 1.000 17.76706  ? 275 ALA A O    1 
ATOM   4208 C  CB   . ALA A 1 295 ? 7.34316   -10.51009 -20.57399 1.000 20.08463  ? 275 ALA A CB   1 
ATOM   4209 H  H    . ALA A 1 295 ? 7.64193   -13.29209 -20.43361 1.000 20.85002  ? 275 ALA A H    1 
ATOM   4210 H  HA   . ALA A 1 295 ? 9.05881   -11.67924 -20.51371 1.000 23.25541  ? 275 ALA A HA   1 
ATOM   4211 H  HB1  . ALA A 1 295 ? 7.81463   -9.67709  -20.73124 1.000 24.12531  ? 275 ALA A HB1  1 
ATOM   4212 H  HB2  . ALA A 1 295 ? 7.02423   -10.87351 -21.41489 1.000 24.12531  ? 275 ALA A HB2  1 
ATOM   4213 H  HB3  . ALA A 1 295 ? 6.59589   -10.35911 -19.97425 1.000 24.12531  ? 275 ALA A HB3  1 
ATOM   4214 N  N    . PRO A 1 296 ? 9.93948   -11.53491 -18.12478 1.000 16.52092  ? 276 PRO A N    1 
ATOM   4215 C  CA   . PRO A 1 296 ? 10.44416  -11.09174 -16.81253 1.000 19.23617  ? 276 PRO A CA   1 
ATOM   4216 C  C    . PRO A 1 296 ? 10.85956  -9.65036  -16.77423 1.000 17.79629  ? 276 PRO A C    1 
ATOM   4217 O  O    . PRO A 1 296 ? 10.63558  -9.00457  -15.74957 1.000 19.88754  ? 276 PRO A O    1 
ATOM   4218 C  CB   . PRO A 1 296 ? 11.65504  -12.00020 -16.56649 1.000 22.26823  ? 276 PRO A CB   1 
ATOM   4219 C  CG   . PRO A 1 296 ? 11.41398  -13.18061 -17.39643 1.000 21.07439  ? 276 PRO A CG   1 
ATOM   4220 C  CD   . PRO A 1 296 ? 10.66406  -12.69710 -18.63218 1.000 18.77962  ? 276 PRO A CD   1 
ATOM   4221 H  HA   . PRO A 1 296 ? 9.75713   -11.25645 -16.14788 1.000 23.10716  ? 276 PRO A HA   1 
ATOM   4222 H  HB2  . PRO A 1 296 ? 12.46897  -11.54639 -16.83571 1.000 26.74564  ? 276 PRO A HB2  1 
ATOM   4223 H  HB3  . PRO A 1 296 ? 11.70357  -12.23942 -15.62770 1.000 26.74564  ? 276 PRO A HB3  1 
ATOM   4224 H  HG2  . PRO A 1 296 ? 12.26191  -13.57972 -17.64666 1.000 25.31303  ? 276 PRO A HG2  1 
ATOM   4225 H  HG3  . PRO A 1 296 ? 10.87900  -13.82098 -16.90183 1.000 25.31303  ? 276 PRO A HG3  1 
ATOM   4226 H  HD2  . PRO A 1 296 ? 11.28040  -12.44327 -19.33686 1.000 22.55930  ? 276 PRO A HD2  1 
ATOM   4227 H  HD3  . PRO A 1 296 ? 10.05135  -13.37585 -18.95590 1.000 22.55930  ? 276 PRO A HD3  1 
ATOM   4228 N  N    . VAL A 1 297 ? 11.42433  -9.12767  -17.86252 1.000 17.47946  ? 277 VAL A N    1 
ATOM   4229 C  CA   . VAL A 1 297 ? 11.75716  -7.70500  -17.97259 1.000 15.87715  ? 277 VAL A CA   1 
ATOM   4230 C  C    . VAL A 1 297 ? 10.50547  -6.99791  -18.48862 1.000 18.38757  ? 277 VAL A C    1 
ATOM   4231 O  O    . VAL A 1 297 ? 10.10806  -7.18547  -19.64509 1.000 18.76215  ? 277 VAL A O    1 
ATOM   4232 C  CB   . VAL A 1 297 ? 12.96544  -7.48226  -18.89945 1.000 16.64770  ? 277 VAL A CB   1 
ATOM   4233 C  CG1  . VAL A 1 297 ? 13.20904  -5.99958  -19.04751 1.000 21.99951  ? 277 VAL A CG1  1 
ATOM   4234 C  CG2  . VAL A 1 297 ? 14.22545  -8.15789  -18.32410 1.000 20.48108  ? 277 VAL A CG2  1 
ATOM   4235 H  H    . VAL A 1 297 ? 11.62829  -9.58344  -18.56272 1.000 20.99912  ? 277 VAL A H    1 
ATOM   4236 H  HA   . VAL A 1 297 ? 11.98238  -7.34334  -17.10116 1.000 19.07634  ? 277 VAL A HA   1 
ATOM   4237 H  HB   . VAL A 1 297 ? 12.77993  -7.87393  -19.76725 1.000 20.00101  ? 277 VAL A HB   1 
ATOM   4238 H  HG11 . VAL A 1 297 ? 14.01273  -5.86252  -19.57305 1.000 26.42318  ? 277 VAL A HG11 1 
ATOM   4239 H  HG12 . VAL A 1 297 ? 12.44832  -5.59775  -19.49554 1.000 26.42318  ? 277 VAL A HG12 1 
ATOM   4240 H  HG13 . VAL A 1 297 ? 13.31893  -5.60811  -18.16684 1.000 26.42318  ? 277 VAL A HG13 1 
ATOM   4241 H  HG21 . VAL A 1 297 ? 14.97870  -7.96825  -18.90509 1.000 24.60106  ? 277 VAL A HG21 1 
ATOM   4242 H  HG22 . VAL A 1 297 ? 14.39538  -7.80547  -17.43650 1.000 24.60106  ? 277 VAL A HG22 1 
ATOM   4243 H  HG23 . VAL A 1 297 ? 14.07684  -9.11528  -18.27700 1.000 24.60106  ? 277 VAL A HG23 1 
ATOM   4244 N  N    . LYS A 1 298 ? 9.85616   -6.22732  -17.60944 1.000 17.42281  ? 278 LYS A N    1 
ATOM   4245 C  CA   . LYS A 1 298 ? 8.56417   -5.61676  -17.95065 1.000 16.92008  ? 278 LYS A CA   1 
ATOM   4246 C  C    . LYS A 1 298 ? 8.73604   -4.38678  -18.83154 1.000 18.89592  ? 278 LYS A C    1 
ATOM   4247 O  O    . LYS A 1 298 ? 7.82698   -4.01774  -19.58680 1.000 18.25097  ? 278 LYS A O    1 
ATOM   4248 C  CB   . LYS A 1 298 ? 7.80188   -5.24113  -16.67586 1.000 16.80469  ? 278 LYS A CB   1 
ATOM   4249 C  CG   . LYS A 1 298 ? 7.52662   -6.44356  -15.74598 1.000 18.40274  ? 278 LYS A CG   1 
ATOM   4250 C  CD   . LYS A 1 298 ? 6.88794   -7.56209  -16.49171 1.000 18.02534  ? 278 LYS A CD   1 
ATOM   4251 C  CE   . LYS A 1 298 ? 6.63227   -8.75677  -15.56184 1.000 20.12024  ? 278 LYS A CE   1 
ATOM   4252 N  NZ   . LYS A 1 298 ? 6.05139   -9.94013  -16.29754 1.000 19.42530  ? 278 LYS A NZ   1 
ATOM   4253 H  H    . LYS A 1 298 ? 10.13740  -6.04358  -16.81777 1.000 20.93114  ? 278 LYS A H    1 
ATOM   4254 H  HA   . LYS A 1 298 ? 8.03156   -6.26654  -18.43543 1.000 20.32786  ? 278 LYS A HA   1 
ATOM   4255 H  HB2  . LYS A 1 298 ? 8.32514   -4.59384  -16.17776 1.000 20.18939  ? 278 LYS A HB2  1 
ATOM   4256 H  HB3  . LYS A 1 298 ? 6.94710   -4.85591  -16.92457 1.000 20.18939  ? 278 LYS A HB3  1 
ATOM   4257 H  HG2  . LYS A 1 298 ? 8.36377   -6.76195  -15.37353 1.000 22.10705  ? 278 LYS A HG2  1 
ATOM   4258 H  HG3  . LYS A 1 298 ? 6.92894   -6.16991  -15.03269 1.000 22.10705  ? 278 LYS A HG3  1 
ATOM   4259 H  HD2  . LYS A 1 298 ? 6.03841   -7.26665  -16.85492 1.000 21.65417  ? 278 LYS A HD2  1 
ATOM   4260 H  HD3  . LYS A 1 298 ? 7.47358   -7.84976  -17.20947 1.000 21.65417  ? 278 LYS A HD3  1 
ATOM   4261 H  HE2  . LYS A 1 298 ? 7.47110   -9.03295  -15.16062 1.000 24.16805  ? 278 LYS A HE2  1 
ATOM   4262 H  HE3  . LYS A 1 298 ? 6.00473   -8.49343  -14.87064 1.000 24.16805  ? 278 LYS A HE3  1 
ATOM   4263 H  HZ1  . LYS A 1 298 ? 5.86731   -10.59494 -15.72357 1.000 23.33412  ? 278 LYS A HZ1  1 
ATOM   4264 H  HZ2  . LYS A 1 298 ? 5.30174   -9.70169  -16.71380 1.000 23.33412  ? 278 LYS A HZ2  1 
ATOM   4265 H  HZ3  . LYS A 1 298 ? 6.63374   -10.23959 -16.90028 1.000 23.33412  ? 278 LYS A HZ3  1 
ATOM   4266 N  N    . ASN A 1 299 ? 9.86292   -3.70163  -18.71380 1.000 18.31529  ? 279 ASN A N    1 
ATOM   4267 C  CA   . ASN A 1 299 ? 10.09459  -2.51696  -19.53205 1.000 18.34137  ? 279 ASN A CA   1 
ATOM   4268 C  C    . ASN A 1 299 ? 11.57333  -2.16179  -19.50138 1.000 19.15815  ? 279 ASN A C    1 
ATOM   4269 O  O    . ASN A 1 299 ? 12.31690  -2.55179  -18.59778 1.000 18.38370  ? 279 ASN A O    1 
ATOM   4270 C  CB   . ASN A 1 299 ? 9.23340   -1.34572  -19.05111 1.000 19.24309  ? 279 ASN A CB   1 
ATOM   4271 C  CG   . ASN A 1 299 ? 9.38275   -1.09325  -17.59094 1.000 20.68855  ? 279 ASN A CG   1 
ATOM   4272 O  OD1  . ASN A 1 299 ? 10.41896  -0.59568  -17.11999 1.000 22.07680  ? 279 ASN A OD1  1 
ATOM   4273 N  ND2  . ASN A 1 299 ? 8.36468   -1.47736  -16.82155 1.000 19.70812  ? 279 ASN A ND2  1 
ATOM   4274 H  H    . ASN A 1 299 ? 10.50315  -3.89803  -18.17423 1.000 22.00211  ? 279 ASN A H    1 
ATOM   4275 H  HA   . ASN A 1 299 ? 9.86601   -2.71068  -20.45461 1.000 22.03340  ? 279 ASN A HA   1 
ATOM   4276 H  HB2  . ASN A 1 299 ? 9.49811   -0.54161  -19.52465 1.000 23.11547  ? 279 ASN A HB2  1 
ATOM   4277 H  HB3  . ASN A 1 299 ? 8.30059   -1.54356  -19.22893 1.000 23.11547  ? 279 ASN A HB3  1 
ATOM   4278 H  HD21 . ASN A 1 299 ? 8.39861   -1.35532  -15.97093 1.000 23.67351  ? 279 ASN A HD21 1 
ATOM   4279 H  HD22 . ASN A 1 299 ? 7.67377   -1.84728  -17.17566 1.000 23.67351  ? 279 ASN A HD22 1 
ATOM   4280 N  N    . MET A 1 300 ? 11.99691  -1.43979  -20.52685 1.000 18.46295  ? 280 MET A N    1 
ATOM   4281 C  CA   . MET A 1 300 ? 13.25214  -0.69356  -20.63341 1.000 18.45599  ? 280 MET A CA   1 
ATOM   4282 C  C    . MET A 1 300 ? 12.86989  0.68546   -21.11093 1.000 18.41923  ? 280 MET A C    1 
ATOM   4283 O  O    . MET A 1 300 ? 11.97791  0.81434   -21.96760 1.000 20.57247  ? 280 MET A O    1 
ATOM   4284 C  CB   . MET A 1 300 ? 14.15433  -1.38028  -21.63683 1.000 19.62308  ? 280 MET A CB   1 
ATOM   4285 C  CG   . MET A 1 300 ? 14.92526  -2.66405  -21.25975 1.000 20.92847  ? 280 MET A CG   1 
ATOM   4286 S  SD   . MET A 1 300 ? 16.25937  -2.47695  -20.09082 1.000 19.65092  ? 280 MET A SD   1 
ATOM   4287 C  CE   . MET A 1 300 ? 16.61794  -4.17193  -19.65457 1.000 20.51026  ? 280 MET A CE   1 
ATOM   4288 H  H    . MET A 1 300 ? 11.53321  -1.35498  -21.24615 1.000 22.17930  ? 280 MET A H    1 
ATOM   4289 H  HA   . MET A 1 300 ? 13.73618  -0.63450  -19.79488 1.000 22.17095  ? 280 MET A HA   1 
ATOM   4290 H  HB2  . MET A 1 300 ? 13.60314  -1.61622  -22.39934 1.000 23.57145  ? 280 MET A HB2  1 
ATOM   4291 H  HB3  . MET A 1 300 ? 14.82795  -0.73448  -21.90155 1.000 23.57145  ? 280 MET A HB3  1 
ATOM   4292 H  HG2  . MET A 1 300 ? 14.29489  -3.29171  -20.87298 1.000 25.13792  ? 280 MET A HG2  1 
ATOM   4293 H  HG3  . MET A 1 300 ? 15.30790  -3.03504  -22.07021 1.000 25.13792  ? 280 MET A HG3  1 
ATOM   4294 H  HE1  . MET A 1 300 ? 17.33674  -4.18514  -19.00338 1.000 24.63607  ? 280 MET A HE1  1 
ATOM   4295 H  HE2  . MET A 1 300 ? 15.82137  -4.57593  -19.27620 1.000 24.63607  ? 280 MET A HE2  1 
ATOM   4296 H  HE3  . MET A 1 300 ? 16.88586  -4.65357  -20.45279 1.000 24.63607  ? 280 MET A HE3  1 
ATOM   4297 N  N    . CYS A 1 301 ? 13.58926  1.70576   -20.62756 1.000 20.46545  ? 281 CYS A N    1 
ATOM   4298 C  CA   . CYS A 1 301 ? 13.28307  3.06012   -21.05287 1.000 19.56415  ? 281 CYS A CA   1 
ATOM   4299 C  C    . CYS A 1 301 ? 14.18143  3.49199   -22.20910 1.000 23.37154  ? 281 CYS A C    1 
ATOM   4300 O  O    . CYS A 1 301 ? 15.27910  2.97324   -22.41821 1.000 21.06121  ? 281 CYS A O    1 
ATOM   4301 C  CB   . CYS A 1 301 ? 13.46822  4.07997   -19.95198 1.000 22.01856  ? 281 CYS A CB   1 
ATOM   4302 S  SG   . CYS A 1 301 ? 12.27094  3.87455   -18.62095 1.000 26.81436  ? 281 CYS A SG   1 
ATOM   4303 H  H    . CYS A 1 301 ? 14.23900  1.63274   -20.06888 1.000 24.58231  ? 281 CYS A H    1 
ATOM   4304 H  HA   . CYS A 1 301 ? 12.35151  3.05354   -21.32314 1.000 23.50074  ? 281 CYS A HA   1 
ATOM   4305 H  HB2  . CYS A 1 301 ? 14.35736  3.98363   -19.57643 1.000 26.44603  ? 281 CYS A HB2  1 
ATOM   4306 H  HB3  . CYS A 1 301 ? 13.35908  4.96988   -20.32219 1.000 26.44603  ? 281 CYS A HB3  1 
ATOM   4307 H  HG   . CYS A 1 301 ? 12.40107  2.78125   -18.14371 1.000 32.20099  ? 281 CYS A HG   1 
ATOM   4308 N  N    . ARG A 1 302 ? 13.69976  4.48534   -22.93172 1.000 20.87033  ? 282 ARG A N    1 
ATOM   4309 C  CA   . ARG A 1 302 ? 14.44876  5.18764   -23.96672 1.000 20.79735  ? 282 ARG A CA   1 
ATOM   4310 C  C    . ARG A 1 302 ? 14.25471  6.68577   -23.72703 1.000 25.99820  ? 282 ARG A C    1 
ATOM   4311 O  O    . ARG A 1 302 ? 13.16690  7.11534   -23.33609 1.000 26.61216  ? 282 ARG A O    1 
ATOM   4312 C  CB   . ARG A 1 302 ? 13.92851  4.84674   -25.39318 1.000 22.30647  ? 282 ARG A CB   1 
ATOM   4313 C  CG   . ARG A 1 302 ? 14.01292  3.38083   -25.80583 1.000 20.62637  ? 282 ARG A CG   1 
ATOM   4314 C  CD   . ARG A 1 302 ? 15.46504  2.94276   -25.95577 1.000 21.83601  ? 282 ARG A CD   1 
ATOM   4315 N  NE   . ARG A 1 302 ? 15.61129  1.54752   -26.39711 1.000 20.16972  ? 282 ARG A NE   1 
ATOM   4316 C  CZ   . ARG A 1 302 ? 15.89782  0.52014   -25.60557 1.000 21.38580  ? 282 ARG A CZ   1 
ATOM   4317 N  NH1  . ARG A 1 302 ? 15.93701  0.64466   -24.28325 1.000 20.20616  ? 282 ARG A NH1  1 
ATOM   4318 N  NH2  . ARG A 1 302 ? 16.18084  -0.65851  -26.16496 1.000 21.49426  ? 282 ARG A NH2  1 
ATOM   4319 H  H    . ARG A 1 302 ? 12.90068  4.78964   -22.83970 1.000 25.06816  ? 282 ARG A H    1 
ATOM   4320 H  HA   . ARG A 1 302 ? 15.38702  4.94553   -23.92248 1.000 24.98059  ? 282 ARG A HA   1 
ATOM   4321 H  HB2  . ARG A 1 302 ? 12.99496  5.10508   -25.44459 1.000 26.79153  ? 282 ARG A HB2  1 
ATOM   4322 H  HB3  . ARG A 1 302 ? 14.44919  5.35493   -26.03469 1.000 26.79153  ? 282 ARG A HB3  1 
ATOM   4323 H  HG2  . ARG A 1 302 ? 13.59348  2.82876   -25.12746 1.000 24.77540  ? 282 ARG A HG2  1 
ATOM   4324 H  HG3  . ARG A 1 302 ? 13.56494  3.25778   -26.65734 1.000 24.77540  ? 282 ARG A HG3  1 
ATOM   4325 H  HD2  . ARG A 1 302 ? 15.89745  3.50933   -26.61374 1.000 26.22697  ? 282 ARG A HD2  1 
ATOM   4326 H  HD3  . ARG A 1 302 ? 15.90971  3.03125   -25.09825 1.000 26.22697  ? 282 ARG A HD3  1 
ATOM   4327 H  HE   . ARG A 1 302 ? 15.50264  1.38382   -27.23436 1.000 24.22742  ? 282 ARG A HE   1 
ATOM   4328 H  HH11 . ARG A 1 302 ? 15.77426  1.40607   -23.91804 1.000 24.27115  ? 282 ARG A HH11 1 
ATOM   4329 H  HH12 . ARG A 1 302 ? 16.12511  -0.03615  -23.79262 1.000 24.27115  ? 282 ARG A HH12 1 
ATOM   4330 H  HH21 . ARG A 1 302 ? 16.17512  -0.74064  -27.02101 1.000 25.81687  ? 282 ARG A HH21 1 
ATOM   4331 H  HH22 . ARG A 1 302 ? 16.36888  -1.33566  -25.66926 1.000 25.81687  ? 282 ARG A HH22 1 
ATOM   4332 N  N    . VAL A 1 303 ? 15.27615  7.50716   -23.97480 1.000 22.86183  ? 283 VAL A N    1 
ATOM   4333 C  CA   . VAL A 1 303 ? 15.14331  8.95707   -23.84462 1.000 25.40751  ? 283 VAL A CA   1 
ATOM   4334 C  C    . VAL A 1 303 ? 15.03803  9.54347   -25.24545 1.000 25.48985  ? 283 VAL A C    1 
ATOM   4335 O  O    . VAL A 1 303 ? 15.78839  9.15509   -26.15635 1.000 26.32060  ? 283 VAL A O    1 
ATOM   4336 C  CB   . VAL A 1 303 ? 16.30225  9.58178   -23.03761 1.000 26.11025  ? 283 VAL A CB   1 
ATOM   4337 C  CG1  . VAL A 1 303 ? 17.65051  9.45585   -23.77807 1.000 29.50693  ? 283 VAL A CG1  1 
ATOM   4338 C  CG2  . VAL A 1 303 ? 15.99453  11.03071  -22.73219 1.000 27.29359  ? 283 VAL A CG2  1 
ATOM   4339 H  H    . VAL A 1 303 ? 16.05785  7.24594   -24.22041 1.000 27.45796  ? 283 VAL A H    1 
ATOM   4340 H  HA   . VAL A 1 303 ? 14.32986  9.16398   -23.35842 1.000 30.51278  ? 283 VAL A HA   1 
ATOM   4341 H  HB   . VAL A 1 303 ? 16.39096  9.09498   -22.20331 1.000 31.35606  ? 283 VAL A HB   1 
ATOM   4342 H  HG11 . VAL A 1 303 ? 18.36585  9.72047   -23.17878 1.000 35.43207  ? 283 VAL A HG11 1 
ATOM   4343 H  HG12 . VAL A 1 303 ? 17.77425  8.53427   -24.05424 1.000 35.43207  ? 283 VAL A HG12 1 
ATOM   4344 H  HG13 . VAL A 1 303 ? 17.63905  10.03551  -24.55574 1.000 35.43207  ? 283 VAL A HG13 1 
ATOM   4345 H  HG21 . VAL A 1 303 ? 16.70302  11.39403  -22.17816 1.000 32.77607  ? 283 VAL A HG21 1 
ATOM   4346 H  HG22 . VAL A 1 303 ? 15.94002  11.52440  -23.56537 1.000 32.77607  ? 283 VAL A HG22 1 
ATOM   4347 H  HG23 . VAL A 1 303 ? 15.14778  11.08134  -22.26170 1.000 32.77607  ? 283 VAL A HG23 1 
ATOM   4348 N  N    . LEU A 1 304 ? 14.09809  10.48301  -25.43853 1.000 25.45883  ? 284 LEU A N    1 
ATOM   4349 C  CA   . LEU A 1 304 ? 13.88372  11.09164  -26.75650 1.000 25.82041  ? 284 LEU A CA   1 
ATOM   4350 C  C    . LEU A 1 304 ? 14.98993  12.10598  -27.04251 1.000 27.35834  ? 284 LEU A C    1 
ATOM   4351 O  O    . LEU A 1 304 ? 15.30695  12.95770  -26.20709 1.000 28.72669  ? 284 LEU A O    1 
ATOM   4352 C  CB   . LEU A 1 304 ? 12.51445  11.77618  -26.83528 1.000 27.29363  ? 284 LEU A CB   1 
ATOM   4353 C  CG   . LEU A 1 304 ? 11.31887  10.89059  -27.24364 1.000 26.36756  ? 284 LEU A CG   1 
ATOM   4354 C  CD1  . LEU A 1 304 ? 11.42785  10.45969  -28.72739 1.000 27.94524  ? 284 LEU A CD1  1 
ATOM   4355 C  CD2  . LEU A 1 304 ? 11.15673  9.69041   -26.31657 1.000 26.53975  ? 284 LEU A CD2  1 
ATOM   4356 H  H    . LEU A 1 304 ? 13.57577  10.78168  -24.82406 1.000 30.57436  ? 284 LEU A H    1 
ATOM   4357 H  HA   . LEU A 1 304 ? 13.90720  10.39604  -27.43214 1.000 31.00825  ? 284 LEU A HA   1 
ATOM   4358 H  HB2  . LEU A 1 304 ? 12.31142  12.14168  -25.96001 1.000 32.77612  ? 284 LEU A HB2  1 
ATOM   4359 H  HB3  . LEU A 1 304 ? 12.57417  12.49144  -27.48777 1.000 32.77612  ? 284 LEU A HB3  1 
ATOM   4360 H  HG   . LEU A 1 304 ? 10.50897  11.41682  -27.15393 1.000 31.66483  ? 284 LEU A HG   1 
ATOM   4361 H  HD11 . LEU A 1 304 ? 10.60883  10.00907  -28.98635 1.000 33.55805  ? 284 LEU A HD11 1 
ATOM   4362 H  HD12 . LEU A 1 304 ? 11.55924  11.24846  -29.27647 1.000 33.55805  ? 284 LEU A HD12 1 
ATOM   4363 H  HD13 . LEU A 1 304 ? 12.18213  9.85798   -28.82691 1.000 33.55805  ? 284 LEU A HD13 1 
ATOM   4364 H  HD21 . LEU A 1 304 ? 10.33860  9.22247   -26.54590 1.000 31.87146  ? 284 LEU A HD21 1 
ATOM   4365 H  HD22 . LEU A 1 304 ? 11.91805  9.09984   -26.42842 1.000 31.87146  ? 284 LEU A HD22 1 
ATOM   4366 H  HD23 . LEU A 1 304 ? 11.11281  10.00341  -25.39950 1.000 31.87146  ? 284 LEU A HD23 1 
ATOM   4367 N  N    . THR A 1 305 ? 15.60194  12.00348  -28.21153 1.000 28.05067  ? 285 THR A N    1 
ATOM   4368 C  CA   . THR A 1 305 ? 16.62130  12.97672  -28.59074 1.000 31.10740  ? 285 THR A CA   1 
ATOM   4369 C  C    . THR A 1 305 ? 16.04092  14.17644  -29.33699 1.000 31.18653  ? 285 THR A C    1 
ATOM   4370 O  O    . THR A 1 305 ? 16.77696  15.13107  -29.63919 1.000 33.37668  ? 285 THR A O    1 
ATOM   4371 C  CB   . THR A 1 305 ? 17.68618  12.31026  -29.45022 1.000 30.86675  ? 285 THR A CB   1 
ATOM   4372 O  OG1  . THR A 1 305 ? 17.08576  11.87697  -30.66278 1.000 32.57174  ? 285 THR A OG1  1 
ATOM   4373 C  CG2  . THR A 1 305 ? 18.31718  11.14564  -28.70380 1.000 31.37493  ? 285 THR A CG2  1 
ATOM   4374 H  H    . THR A 1 305 ? 15.44889  11.39027  -28.79476 1.000 33.68456  ? 285 THR A H    1 
ATOM   4375 H  HA   . THR A 1 305 ? 17.05186  13.30505  -27.78594 1.000 37.35264  ? 285 THR A HA   1 
ATOM   4376 H  HB   . THR A 1 305 ? 18.40039  12.93257  -29.65889 1.000 37.06386  ? 285 THR A HB   1 
ATOM   4377 H  HG1  . THR A 1 305 ? 17.65260  11.47855  -31.13771 1.000 39.10985  ? 285 THR A HG1  1 
ATOM   4378 H  HG21 . THR A 1 305 ? 19.04718  10.77475  -29.22384 1.000 37.67368  ? 285 THR A HG21 1 
ATOM   4379 H  HG22 . THR A 1 305 ? 18.66137  11.44718  -27.84852 1.000 37.67368  ? 285 THR A HG22 1 
ATOM   4380 H  HG23 . THR A 1 305 ? 17.65605  10.45262  -28.55043 1.000 37.67368  ? 285 THR A HG23 1 
ATOM   4381 N  N    . ALA A 1 306 ? 14.74669  14.14907  -29.64473 1.000 30.96308  ? 286 ALA A N    1 
ATOM   4382 C  CA   . ALA A 1 306 ? 14.07175  15.22704  -30.33648 1.000 32.18216  ? 286 ALA A CA   1 
ATOM   4383 C  C    . ALA A 1 306 ? 12.58126  15.07092  -30.09611 1.000 32.67607  ? 286 ALA A C    1 
ATOM   4384 O  O    . ALA A 1 306 ? 12.08992  13.97273  -29.80859 1.000 32.82673  ? 286 ALA A O    1 
ATOM   4385 C  CB   . ALA A 1 306 ? 14.35172  15.20514  -31.83136 1.000 35.45550  ? 286 ALA A CB   1 
ATOM   4386 H  H    . ALA A 1 306 ? 14.22494  13.49236  -29.45473 1.000 37.17946  ? 286 ALA A H    1 
ATOM   4387 H  HA   . ALA A 1 306 ? 14.37529  16.07661  -29.98013 1.000 38.64235  ? 286 ALA A HA   1 
ATOM   4388 H  HB1  . ALA A 1 306 ? 13.87761  15.93929  -32.25223 1.000 42.57036  ? 286 ALA A HB1  1 
ATOM   4389 H  HB2  . ALA A 1 306 ? 15.30609  15.30186  -31.97536 1.000 42.57036  ? 286 ALA A HB2  1 
ATOM   4390 H  HB3  . ALA A 1 306 ? 14.04586  14.36061  -32.19759 1.000 42.57036  ? 286 ALA A HB3  1 
ATOM   4391 N  N    . ASP A 1 307 ? 11.86413  16.18470  -30.23810 1.000 33.92195  ? 287 ASP A N    1 
ATOM   4392 C  CA   . ASP A 1 307 ? 10.41208  16.12381  -30.28364 1.000 33.14213  ? 287 ASP A CA   1 
ATOM   4393 C  C    . ASP A 1 307 ? 9.98959   15.27757  -31.47242 1.000 35.08981  ? 287 ASP A C    1 
ATOM   4394 O  O    . ASP A 1 307 ? 10.58648  15.36465  -32.54754 1.000 36.94795  ? 287 ASP A O    1 
ATOM   4395 C  CB   . ASP A 1 307 ? 9.81454   17.52644  -30.45235 1.000 32.43963  ? 287 ASP A CB   1 
ATOM   4396 C  CG   . ASP A 1 307 ? 10.16555  18.47977  -29.34064 1.000 37.16517  ? 287 ASP A CG   1 
ATOM   4397 O  OD1  . ASP A 1 307 ? 10.54855  18.08096  -28.23937 1.000 34.08126  ? 287 ASP A OD1  1 
ATOM   4398 O  OD2  . ASP A 1 307 ? 10.07013  19.68905  -29.59188 1.000 46.88674  ? 287 ASP A OD2  1 
ATOM   4399 H  H    . ASP A 1 307 ? 12.19287  16.97622  -30.30903 1.000 40.73010  ? 287 ASP A H    1 
ATOM   4400 H  HA   . ASP A 1 307 ? 10.07911  15.74344  -29.45578 1.000 39.79432  ? 287 ASP A HA   1 
ATOM   4401 H  HB2  . ASP A 1 307 ? 10.14332  17.90715  -31.28172 1.000 38.95132  ? 287 ASP A HB2  1 
ATOM   4402 H  HB3  . ASP A 1 307 ? 8.84789   17.45148  -30.48194 1.000 38.95132  ? 287 ASP A HB3  1 
ATOM   4403 N  N    . THR A 1 308 ? 8.94449   14.47382  -31.29603 1.000 31.07689  ? 288 THR A N    1 
ATOM   4404 C  CA   . THR A 1 308 ? 8.52311   13.61085  -32.38456 1.000 32.97823  ? 288 THR A CA   1 
ATOM   4405 C  C    . THR A 1 308 ? 7.07757   13.18833  -32.17904 1.000 30.63720  ? 288 THR A C    1 
ATOM   4406 O  O    . THR A 1 308 ? 6.60626   13.05318  -31.04787 1.000 29.56395  ? 288 THR A O    1 
ATOM   4407 C  CB   . THR A 1 308 ? 9.45995   12.39660  -32.47459 1.000 32.14627  ? 288 THR A CB   1 
ATOM   4408 O  OG1  . THR A 1 308 ? 9.35217   11.77538  -33.77319 1.000 36.61961  ? 288 THR A OG1  1 
ATOM   4409 C  CG2  . THR A 1 308 ? 9.14033   11.39140  -31.41222 1.000 29.40932  ? 288 THR A CG2  1 
ATOM   4410 H  H    . THR A 1 308 ? 8.47922   14.41447  -30.57520 1.000 37.31603  ? 288 THR A H    1 
ATOM   4411 H  HA   . THR A 1 308 ? 8.54583   14.09229  -33.22634 1.000 39.59764  ? 288 THR A HA   1 
ATOM   4412 H  HB   . THR A 1 308 ? 10.37258  12.69743  -32.34230 1.000 38.59929  ? 288 THR A HB   1 
ATOM   4413 H  HG1  . THR A 1 308 ? 8.58986   11.43512  -33.86652 1.000 43.96729  ? 288 THR A HG1  1 
ATOM   4414 H  HG21 . THR A 1 308 ? 9.87928   10.77160  -31.30885 1.000 35.31495  ? 288 THR A HG21 1 
ATOM   4415 H  HG22 . THR A 1 308 ? 8.98540   11.84041  -30.56648 1.000 35.31495  ? 288 THR A HG22 1 
ATOM   4416 H  HG23 . THR A 1 308 ? 8.34381   10.89392  -31.65506 1.000 35.31495  ? 288 THR A HG23 1 
ATOM   4417 N  N    . GLU A 1 309 ? 6.36988   13.03321  -33.29732 1.000 28.15337  ? 289 GLU A N    1 
ATOM   4418 C  CA   . GLU A 1 309 ? 5.03526   12.46391  -33.30996 1.000 26.56063  ? 289 GLU A CA   1 
ATOM   4419 C  C    . GLU A 1 309 ? 5.18900   10.96979  -33.57887 1.000 28.71933  ? 289 GLU A C    1 
ATOM   4420 O  O    . GLU A 1 309 ? 5.65929   10.58835  -34.65663 1.000 31.16144  ? 289 GLU A O    1 
ATOM   4421 C  CB   . GLU A 1 309 ? 4.18834   13.12675  -34.38693 1.000 29.17475  ? 289 GLU A CB   1 
ATOM   4422 C  CG   . GLU A 1 309 ? 2.86226   12.47025  -34.58733 1.000 32.17207  ? 289 GLU A CG   1 
ATOM   4423 C  CD   . GLU A 1 309 ? 1.86015   12.74776  -33.49736 1.000 32.71040  ? 289 GLU A CD   1 
ATOM   4424 O  OE1  . GLU A 1 309 ? 2.04853   13.67256  -32.66062 1.000 32.04994  ? 289 GLU A OE1  1 
ATOM   4425 O  OE2  . GLU A 1 309 ? 0.81702   12.04937  -33.51263 1.000 34.56738  ? 289 GLU A OE2  1 
ATOM   4426 H  H    . GLU A 1 309 ? 6.65305   13.25741  -34.07780 1.000 33.80780  ? 289 GLU A H    1 
ATOM   4427 H  HA   . GLU A 1 309 ? 4.58762   12.59852  -32.46002 1.000 31.89652  ? 289 GLU A HA   1 
ATOM   4428 H  HB2  . GLU A 1 309 ? 4.02836   14.04982  -34.13542 1.000 35.03346  ? 289 GLU A HB2  1 
ATOM   4429 H  HB3  . GLU A 1 309 ? 4.66843   13.09077  -35.22902 1.000 35.03346  ? 289 GLU A HB3  1 
ATOM   4430 H  HG2  . GLU A 1 309 ? 2.48269   12.78693  -35.42193 1.000 38.63025  ? 289 GLU A HG2  1 
ATOM   4431 H  HG3  . GLU A 1 309 ? 2.99456   11.51010  -34.62624 1.000 38.63025  ? 289 GLU A HG3  1 
ATOM   4432 N  N    . PHE A 1 310 ? 4.79216   10.14590  -32.61522 1.000 25.93473  ? 290 PHE A N    1 
ATOM   4433 C  CA   . PHE A 1 310 ? 5.09418   8.70970   -32.62752 1.000 24.04698  ? 290 PHE A CA   1 
ATOM   4434 C  C    . PHE A 1 310 ? 3.82378   7.90963   -32.41905 1.000 23.20310  ? 290 PHE A C    1 
ATOM   4435 O  O    . PHE A 1 310 ? 3.29547   7.85020   -31.30761 1.000 23.63350  ? 290 PHE A O    1 
ATOM   4436 C  CB   . PHE A 1 310 ? 6.13820   8.37255   -31.55659 1.000 25.19561  ? 290 PHE A CB   1 
ATOM   4437 C  CG   . PHE A 1 310 ? 6.62482   6.94202   -31.60502 1.000 22.38344  ? 290 PHE A CG   1 
ATOM   4438 C  CD1  . PHE A 1 310 ? 7.25388   6.47400   -32.74308 1.000 25.01253  ? 290 PHE A CD1  1 
ATOM   4439 C  CD2  . PHE A 1 310 ? 6.42351   6.09706   -30.54856 1.000 22.93450  ? 290 PHE A CD2  1 
ATOM   4440 C  CE1  . PHE A 1 310 ? 7.71407   5.15740   -32.80587 1.000 27.32862  ? 290 PHE A CE1  1 
ATOM   4441 C  CE2  . PHE A 1 310 ? 6.87879   4.77290   -30.59780 1.000 23.43732  ? 290 PHE A CE2  1 
ATOM   4442 C  CZ   . PHE A 1 310 ? 7.52642   4.32561   -31.73271 1.000 23.89513  ? 290 PHE A CZ   1 
ATOM   4443 H  H    . PHE A 1 310 ? 4.33789   10.39571  -31.92904 1.000 31.14543  ? 290 PHE A H    1 
ATOM   4444 H  HA   . PHE A 1 310 ? 5.43876   8.47010   -33.50202 1.000 28.88014  ? 290 PHE A HA   1 
ATOM   4445 H  HB2  . PHE A 1 310 ? 6.90747   8.95066   -31.67874 1.000 30.25849  ? 290 PHE A HB2  1 
ATOM   4446 H  HB3  . PHE A 1 310 ? 5.74647   8.52198   -30.68188 1.000 30.25849  ? 290 PHE A HB3  1 
ATOM   4447 H  HD1  . PHE A 1 310 ? 7.37142   7.03973   -33.47180 1.000 30.03880  ? 290 PHE A HD1  1 
ATOM   4448 H  HD2  . PHE A 1 310 ? 5.98046   6.40418   -29.79074 1.000 27.54516  ? 290 PHE A HD2  1 
ATOM   4449 H  HE1  . PHE A 1 310 ? 8.14448   4.84723   -33.56970 1.000 32.81811  ? 290 PHE A HE1  1 
ATOM   4450 H  HE2  . PHE A 1 310 ? 6.74656   4.20235   -29.87538 1.000 28.14854  ? 290 PHE A HE2  1 
ATOM   4451 H  HZ   . PHE A 1 310 ? 7.83866   3.45035   -31.76919 1.000 28.69791  ? 290 PHE A HZ   1 
ATOM   4452 N  N    . HIS A 1 311 ? 3.35154   7.26063   -33.48488 1.000 25.53038  ? 291 HIS A N    1 
ATOM   4453 C  CA   . HIS A 1 311 ? 2.14955   6.41758   -33.43880 1.000 25.79279  ? 291 HIS A CA   1 
ATOM   4454 C  C    . HIS A 1 311 ? 1.00395   7.11742   -32.70805 1.000 24.90827  ? 291 HIS A C    1 
ATOM   4455 O  O    . HIS A 1 311 ? 0.32083   6.51937   -31.86376 1.000 25.91533  ? 291 HIS A O    1 
ATOM   4456 C  CB   . HIS A 1 311 ? 2.43400   5.04719   -32.81896 1.000 24.98625  ? 291 HIS A CB   1 
ATOM   4457 C  CG   . HIS A 1 311 ? 3.11508   4.11140   -33.76484 1.000 25.32887  ? 291 HIS A CG   1 
ATOM   4458 N  ND1  . HIS A 1 311 ? 2.47124   3.54717   -34.84821 1.000 27.91097  ? 291 HIS A ND1  1 
ATOM   4459 C  CD2  . HIS A 1 311 ? 4.40315   3.70190   -33.83553 1.000 26.65769  ? 291 HIS A CD2  1 
ATOM   4460 C  CE1  . HIS A 1 311 ? 3.33119   2.81502   -35.53364 1.000 31.74948  ? 291 HIS A CE1  1 
ATOM   4461 N  NE2  . HIS A 1 311 ? 4.51086   2.89133   -34.93792 1.000 28.58642  ? 291 HIS A NE2  1 
ATOM   4462 H  H    . HIS A 1 311 ? 3.71575   7.29196   -34.26332 1.000 30.66022  ? 291 HIS A H    1 
ATOM   4463 H  HA   . HIS A 1 311 ? 1.86876   6.26987   -34.35545 1.000 30.97511  ? 291 HIS A HA   1 
ATOM   4464 H  HB2  . HIS A 1 311 ? 3.00906   5.16380   -32.04656 1.000 30.00726  ? 291 HIS A HB2  1 
ATOM   4465 H  HB3  . HIS A 1 311 ? 1.59454   4.64268   -32.54954 1.000 30.00726  ? 291 HIS A HB3  1 
ATOM   4466 H  HD2  . HIS A 1 311 ? 5.08721   3.92751   -33.24726 1.000 32.01299  ? 291 HIS A HD2  1 
ATOM   4467 H  HE1  . HIS A 1 311 ? 3.14037   2.32901   -36.30323 1.000 38.12314  ? 291 HIS A HE1  1 
ATOM   4468 H  HE2  . HIS A 1 311 ? 5.22884   2.49673   -35.19943 1.000 34.32747  ? 291 HIS A HE2  1 
ATOM   4469 N  N    . GLY A 1 312 ? 0.80176   8.39567   -33.07330 1.000 25.48723  ? 292 GLY A N    1 
ATOM   4470 C  CA   . GLY A 1 312 ? -0.31943  9.19761   -32.62857 1.000 25.64267  ? 292 GLY A CA   1 
ATOM   4471 C  C    . GLY A 1 312 ? -0.11428  10.02226  -31.36243 1.000 27.98581  ? 292 GLY A C    1 
ATOM   4472 O  O    . GLY A 1 312 ? -1.01445  10.79035  -31.00783 1.000 28.33031  ? 292 GLY A O    1 
ATOM   4473 H  H    . GLY A 1 312 ? 1.32852   8.82614   -33.59944 1.000 30.60843  ? 292 GLY A H    1 
ATOM   4474 H  HA2  . GLY A 1 312 ? -0.55113  9.81528   -33.33969 1.000 30.79497  ? 292 GLY A HA2  1 
ATOM   4475 H  HA3  . GLY A 1 312 ? -1.07056  8.60536   -32.46749 1.000 30.79497  ? 292 GLY A HA3  1 
ATOM   4476 N  N    . THR A 1 313 ? 1.03070   9.90369   -30.68806 1.000 24.77382  ? 293 THR A N    1 
ATOM   4477 C  CA   . THR A 1 313 ? 1.28508   10.60869  -29.43673 1.000 24.64566  ? 293 THR A CA   1 
ATOM   4478 C  C    . THR A 1 313 ? 2.48611   11.53267  -29.60451 1.000 26.67277  ? 293 THR A C    1 
ATOM   4479 O  O    . THR A 1 313 ? 3.54520   11.10285  -30.07470 1.000 25.17094  ? 293 THR A O    1 
ATOM   4480 C  CB   . THR A 1 313 ? 1.52040   9.60448   -28.30140 1.000 25.19306  ? 293 THR A CB   1 
ATOM   4481 O  OG1  . THR A 1 313 ? 0.30894   8.86096   -28.08560 1.000 25.58506  ? 293 THR A OG1  1 
ATOM   4482 C  CG2  . THR A 1 313 ? 1.87568   10.34636  -27.02344 1.000 24.82626  ? 293 THR A CG2  1 
ATOM   4483 H  H    . THR A 1 313 ? 1.68680   9.40973   -30.94327 1.000 29.75235  ? 293 THR A H    1 
ATOM   4484 H  HA   . THR A 1 313 ? 0.52385   11.16378  -29.20584 1.000 29.59855  ? 293 THR A HA   1 
ATOM   4485 H  HB   . THR A 1 313 ? 2.24622   9.00220   -28.52799 1.000 30.25544  ? 293 THR A HB   1 
ATOM   4486 H  HG1  . THR A 1 313 ? 0.40896   8.32886   -27.44337 1.000 30.72584  ? 293 THR A HG1  1 
ATOM   4487 H  HG21 . THR A 1 313 ? 1.73497   9.77064   -26.25556 1.000 29.81528  ? 293 THR A HG21 1 
ATOM   4488 H  HG22 . THR A 1 313 ? 2.80624   10.61922  -27.04600 1.000 29.81528  ? 293 THR A HG22 1 
ATOM   4489 H  HG23 . THR A 1 313 ? 1.31849   11.13507  -26.93186 1.000 29.81528  ? 293 THR A HG23 1 
ATOM   4490 N  N    . ALA A 1 314 ? 2.32732   12.78820  -29.18412 1.000 24.10189  ? 294 ALA A N    1 
ATOM   4491 C  CA   . ALA A 1 314 ? 3.39484   13.77878  -29.24031 1.000 25.76265  ? 294 ALA A CA   1 
ATOM   4492 C  C    . ALA A 1 314 ? 4.37702   13.50019  -28.11730 1.000 28.34921  ? 294 ALA A C    1 
ATOM   4493 O  O    . ALA A 1 314 ? 3.96823   13.39975  -26.96220 1.000 26.73685  ? 294 ALA A O    1 
ATOM   4494 C  CB   . ALA A 1 314 ? 2.82537   15.19003  -29.09304 1.000 28.33654  ? 294 ALA A CB   1 
ATOM   4495 H  H    . ALA A 1 314 ? 1.59424   13.09520  -28.85558 1.000 28.94603  ? 294 ALA A H    1 
ATOM   4496 H  HA   . ALA A 1 314 ? 3.85179   13.72717  -30.09437 1.000 30.93895  ? 294 ALA A HA   1 
ATOM   4497 H  HB1  . ALA A 1 314 ? 3.55583   15.82814  -29.10477 1.000 34.02762  ? 294 ALA A HB1  1 
ATOM   4498 H  HB2  . ALA A 1 314 ? 2.22111   15.36537  -29.83130 1.000 34.02762  ? 294 ALA A HB2  1 
ATOM   4499 H  HB3  . ALA A 1 314 ? 2.34630   15.25107  -28.25182 1.000 34.02762  ? 294 ALA A HB3  1 
ATOM   4500 N  N    . LEU A 1 315 ? 5.65573   13.34944  -28.45371 1.000 26.85112  ? 295 LEU A N    1 
ATOM   4501 C  CA   . LEU A 1 315 ? 6.70661   13.12234  -27.46661 1.000 25.60197  ? 295 LEU A CA   1 
ATOM   4502 C  C    . LEU A 1 315 ? 7.71631   14.26013  -27.50068 1.000 27.51994  ? 295 LEU A C    1 
ATOM   4503 O  O    . LEU A 1 315 ? 7.95042   14.86344  -28.54832 1.000 30.11263  ? 295 LEU A O    1 
ATOM   4504 C  CB   . LEU A 1 315 ? 7.41841   11.80349  -27.70974 1.000 26.47366  ? 295 LEU A CB   1 
ATOM   4505 C  CG   . LEU A 1 315 ? 6.53838   10.55453  -27.73824 1.000 25.27828  ? 295 LEU A CG   1 
ATOM   4506 C  CD1  . LEU A 1 315 ? 7.36967   9.35029   -28.21381 1.000 25.79488  ? 295 LEU A CD1  1 
ATOM   4507 C  CD2  . LEU A 1 315 ? 5.93262   10.30867  -26.40266 1.000 25.15468  ? 295 LEU A CD2  1 
ATOM   4508 H  H    . LEU A 1 315 ? 5.94409   13.37538  -29.26350 1.000 32.24510  ? 295 LEU A H    1 
ATOM   4509 H  HA   . LEU A 1 315 ? 6.31012   13.09738  -26.58170 1.000 30.74613  ? 295 LEU A HA   1 
ATOM   4510 H  HB2  . LEU A 1 315 ? 7.86682   11.85697  -28.56821 1.000 31.79215  ? 295 LEU A HB2  1 
ATOM   4511 H  HB3  . LEU A 1 315 ? 8.07009   11.67800  -27.00230 1.000 31.79215  ? 295 LEU A HB3  1 
ATOM   4512 H  HG   . LEU A 1 315 ? 5.80574   10.67997  -28.36147 1.000 30.35770  ? 295 LEU A HG   1 
ATOM   4513 H  HD11 . LEU A 1 315 ? 6.79487   8.57070   -28.26622 1.000 30.97761  ? 295 LEU A HD11 1 
ATOM   4514 H  HD12 . LEU A 1 315 ? 7.73984   9.54771   -29.08840 1.000 30.97761  ? 295 LEU A HD12 1 
ATOM   4515 H  HD13 . LEU A 1 315 ? 8.08616   9.19095   -27.57965 1.000 30.97761  ? 295 LEU A HD13 1 
ATOM   4516 H  HD21 . LEU A 1 315 ? 5.43883   9.47417   -26.42863 1.000 30.20938  ? 295 LEU A HD21 1 
ATOM   4517 H  HD22 . LEU A 1 315 ? 6.63937   10.25436  -25.74051 1.000 30.20938  ? 295 LEU A HD22 1 
ATOM   4518 H  HD23 . LEU A 1 315 ? 5.33371   11.04085  -26.18792 1.000 30.20938  ? 295 LEU A HD23 1 
ATOM   4519 N  N    . CYS A 1 316 ? 8.27992   14.58097  -26.33893 1.000 29.49995  ? 296 CYS A N    1 
ATOM   4520 C  CA   . CYS A 1 316 ? 9.15822   15.73182  -26.18849 1.000 31.28921  ? 296 CYS A CA   1 
ATOM   4521 C  C    . CYS A 1 316 ? 10.61010  15.32316  -25.97202 1.000 30.04407  ? 296 CYS A C    1 
ATOM   4522 O  O    . CYS A 1 316 ? 10.90763  14.36494  -25.25160 1.000 28.84646  ? 296 CYS A O    1 
ATOM   4523 C  CB   . CYS A 1 316 ? 8.71842   16.61524  -25.01316 1.000 37.65503  ? 296 CYS A CB   1 
ATOM   4524 S  SG   . CYS A 1 316 ? 6.98820   17.11603  -25.10083 1.000 48.77049  ? 296 CYS A SG   1 
ATOM   4525 H  H    . CYS A 1 316 ? 8.16471   14.13701  -25.61145 1.000 35.42370  ? 296 CYS A H    1 
ATOM   4526 H  HA   . CYS A 1 316 ? 9.11579   16.23808  -27.01480 1.000 37.57081  ? 296 CYS A HA   1 
ATOM   4527 H  HB2  . CYS A 1 316 ? 8.84419   16.12258  -24.18711 1.000 45.20979  ? 296 CYS A HB2  1 
ATOM   4528 H  HB3  . CYS A 1 316 ? 9.26098   17.41928  -25.00581 1.000 45.20979  ? 296 CYS A HB3  1 
ATOM   4529 H  HG   . CYS A 1 316 ? 6.73581   17.81573  -24.15917 1.000 58.54835  ? 296 CYS A HG   1 
ATOM   4530 N  N    . ALA A 1 317 ? 11.51537  16.07415  -26.59431 1.000 30.99963  ? 297 ALA A N    1 
ATOM   4531 C  CA   . ALA A 1 317 ? 12.93882  15.85451  -26.37543 1.000 33.18892  ? 297 ALA A CA   1 
ATOM   4532 C  C    . ALA A 1 317 ? 13.26874  15.81212  -24.88747 1.000 31.28824  ? 297 ALA A C    1 
ATOM   4533 O  O    . ALA A 1 317 ? 12.85166  16.67701  -24.10827 1.000 34.28856  ? 297 ALA A O    1 
ATOM   4534 C  CB   . ALA A 1 317 ? 13.74265  16.95890  -27.05855 1.000 37.52261  ? 297 ALA A CB   1 
ATOM   4535 H  H    . ALA A 1 317 ? 11.33174  16.71077  -27.14258 1.000 37.22332  ? 297 ALA A H    1 
ATOM   4536 H  HA   . ALA A 1 317 ? 13.18923  15.00117  -26.76274 1.000 39.85046  ? 297 ALA A HA   1 
ATOM   4537 H  HB1  . ALA A 1 317 ? 14.68699  16.80969  -26.89462 1.000 45.05090  ? 297 ALA A HB1  1 
ATOM   4538 H  HB2  . ALA A 1 317 ? 13.56467  16.93553  -28.01180 1.000 45.05090  ? 297 ALA A HB2  1 
ATOM   4539 H  HB3  . ALA A 1 317 ? 13.47495  17.81658  -26.69300 1.000 45.05090  ? 297 ALA A HB3  1 
ATOM   4540 N  N    . GLY A 1 318 ? 14.04169  14.81660  -24.50162 1.000 32.27310  ? 298 GLY A N    1 
ATOM   4541 C  CA   . GLY A 1 318 ? 14.49652  14.68634  -23.12446 1.000 31.00374  ? 298 GLY A CA   1 
ATOM   4542 C  C    . GLY A 1 318 ? 13.61203  13.87720  -22.19593 1.000 30.48600  ? 298 GLY A C    1 
ATOM   4543 O  O    . GLY A 1 318 ? 14.07437  13.53628  -21.08898 1.000 29.48150  ? 298 GLY A O    1 
ATOM   4544 H  H    . GLY A 1 318 ? 14.32260  14.19283  -25.02277 1.000 38.75148  ? 298 GLY A H    1 
ATOM   4545 H  HA2  . GLY A 1 318 ? 15.37040  14.26540  -23.13098 1.000 37.22825  ? 298 GLY A HA2  1 
ATOM   4546 H  HA3  . GLY A 1 318 ? 14.57709  15.57543  -22.74507 1.000 37.22825  ? 298 GLY A HA3  1 
ATOM   4547 N  N    . GLU A 1 319 ? 12.36838  13.57859  -22.58182 1.000 29.87724  ? 299 GLU A N    1 
ATOM   4548 C  CA   . GLU A 1 319 ? 11.55426  12.69890  -21.74392 1.000 26.84018  ? 299 GLU A CA   1 
ATOM   4549 C  C    . GLU A 1 319 ? 11.87303  11.23522  -22.03852 1.000 25.62466  ? 299 GLU A C    1 
ATOM   4550 O  O    . GLU A 1 319 ? 12.40874  10.89761  -23.10128 1.000 27.14579  ? 299 GLU A O    1 
ATOM   4551 C  CB   . GLU A 1 319 ? 10.05867  12.97905  -21.90891 1.000 29.60889  ? 299 GLU A CB   1 
ATOM   4552 C  CG   . GLU A 1 319 ? 9.38426   12.39853  -23.11448 1.000 27.39096  ? 299 GLU A CG   1 
ATOM   4553 C  CD   . GLU A 1 319 ? 7.87599   12.59684  -23.09168 1.000 34.02055  ? 299 GLU A CD   1 
ATOM   4554 O  OE1  . GLU A 1 319 ? 7.23811   12.25504  -22.07938 1.000 32.22667  ? 299 GLU A OE1  1 
ATOM   4555 O  OE2  . GLU A 1 319 ? 7.33064   13.11621  -24.08492 1.000 30.10440  ? 299 GLU A OE2  1 
ATOM   4556 H  H    . GLU A 1 319 ? 11.98801  13.86303  -23.29877 1.000 35.87645  ? 299 GLU A H    1 
ATOM   4557 H  HA   . GLU A 1 319 ? 11.76423  12.86997  -20.81250 1.000 32.23197  ? 299 GLU A HA   1 
ATOM   4558 H  HB2  . GLU A 1 319 ? 9.60059   12.62351  -21.13131 1.000 35.55443  ? 299 GLU A HB2  1 
ATOM   4559 H  HB3  . GLU A 1 319 ? 9.93805   13.94045  -21.95423 1.000 35.55443  ? 299 GLU A HB3  1 
ATOM   4560 H  HG2  . GLU A 1 319 ? 9.73232   12.82970  -23.91063 1.000 32.89292  ? 299 GLU A HG2  1 
ATOM   4561 H  HG3  . GLU A 1 319 ? 9.56184   11.44554  -23.14875 1.000 32.89292  ? 299 GLU A HG3  1 
ATOM   4562 N  N    . LYS A 1 320 ? 11.53888  10.36504  -21.07746 1.000 25.77395  ? 300 LYS A N    1 
ATOM   4563 C  CA   . LYS A 1 320 ? 11.74276  8.92886   -21.23461 1.000 22.46646  ? 300 LYS A CA   1 
ATOM   4564 C  C    . LYS A 1 320 ? 10.42636  8.25420   -21.57417 1.000 25.41727  ? 300 LYS A C    1 
ATOM   4565 O  O    . LYS A 1 320 ? 9.36080   8.66488   -21.08509 1.000 31.20445  ? 300 LYS A O    1 
ATOM   4566 C  CB   . LYS A 1 320 ? 12.35024  8.31709   -19.97828 1.000 26.67212  ? 300 LYS A CB   1 
ATOM   4567 C  CG   . LYS A 1 320 ? 13.85708  8.45835   -19.97238 1.000 28.26207  ? 300 LYS A CG   1 
ATOM   4568 C  CD   . LYS A 1 320 ? 14.44573  7.90089   -18.70121 1.000 29.83948  ? 300 LYS A CD   1 
ATOM   4569 C  CE   . LYS A 1 320 ? 15.94584  8.08022   -18.68226 1.000 26.81665  ? 300 LYS A CE   1 
ATOM   4570 N  NZ   . LYS A 1 320 ? 16.61046  7.57963   -17.42778 1.000 25.91538  ? 300 LYS A NZ   1 
ATOM   4571 H  H    . LYS A 1 320 ? 11.19100  10.58871  -20.32343 1.000 30.95250  ? 300 LYS A H    1 
ATOM   4572 H  HA   . LYS A 1 320 ? 12.36038  8.76748   -21.96495 1.000 26.98351  ? 300 LYS A HA   1 
ATOM   4573 H  HB2  . LYS A 1 320 ? 11.99669  8.77023   -19.19689 1.000 32.03031  ? 300 LYS A HB2  1 
ATOM   4574 H  HB3  . LYS A 1 320 ? 12.13058  7.37299   -19.94201 1.000 32.03031  ? 300 LYS A HB3  1 
ATOM   4575 H  HG2  . LYS A 1 320 ? 14.23054  7.97104   -20.72336 1.000 33.93824  ? 300 LYS A HG2  1 
ATOM   4576 H  HG3  . LYS A 1 320 ? 14.09418  9.39684   -20.03494 1.000 33.93824  ? 300 LYS A HG3  1 
ATOM   4577 H  HD2  . LYS A 1 320 ? 14.07011  8.36741   -17.93821 1.000 35.83114  ? 300 LYS A HD2  1 
ATOM   4578 H  HD3  . LYS A 1 320 ? 14.24805  6.95317   -18.64082 1.000 35.83114  ? 300 LYS A HD3  1 
ATOM   4579 H  HE2  . LYS A 1 320 ? 16.32654  7.59411   -19.43037 1.000 32.20375  ? 300 LYS A HE2  1 
ATOM   4580 H  HE3  . LYS A 1 320 ? 16.14700  9.02560   -18.76404 1.000 32.20375  ? 300 LYS A HE3  1 
ATOM   4581 H  HZ1  . LYS A 1 320 ? 16.26924  7.99248   -16.71699 1.000 31.12222  ? 300 LYS A HZ1  1 
ATOM   4582 H  HZ2  . LYS A 1 320 ? 16.48001  6.70333   -17.34308 1.000 31.12222  ? 300 LYS A HZ2  1 
ATOM   4583 H  HZ3  . LYS A 1 320 ? 17.48532  7.73941   -17.46225 1.000 31.12222  ? 300 LYS A HZ3  1 
ATOM   4584 N  N    . MET A 1 321 ? 10.51439  7.25510   -22.45263 1.000 22.92601  ? 301 MET A N    1 
ATOM   4585 C  CA   . MET A 1 321 ? 9.39247   6.41391   -22.85172 1.000 21.12640  ? 301 MET A CA   1 
ATOM   4586 C  C    . MET A 1 321 ? 9.70550   4.97755   -22.48428 1.000 22.97430  ? 301 MET A C    1 
ATOM   4587 O  O    . MET A 1 321 ? 10.79965  4.49200   -22.78954 1.000 22.52968  ? 301 MET A O    1 
ATOM   4588 C  CB   . MET A 1 321 ? 9.11221   6.51759   -24.35033 1.000 22.43218  ? 301 MET A CB   1 
ATOM   4589 C  CG   . MET A 1 321 ? 7.79850   5.83631   -24.79239 1.000 22.62711  ? 301 MET A CG   1 
ATOM   4590 S  SD   . MET A 1 321 ? 7.61706   5.68287   -26.57889 1.000 25.33982  ? 301 MET A SD   1 
ATOM   4591 C  CE   . MET A 1 321 ? 8.84142   4.43878   -26.98336 1.000 24.03047  ? 301 MET A CE   1 
ATOM   4592 H  H    . MET A 1 321 ? 11.24729  7.03800   -22.84673 1.000 27.53498  ? 301 MET A H    1 
ATOM   4593 H  HA   . MET A 1 321 ? 8.59594   6.70797   -22.38270 1.000 25.37544  ? 301 MET A HA   1 
ATOM   4594 H  HB2  . MET A 1 321 ? 9.05400   7.45532   -24.59154 1.000 26.94238  ? 301 MET A HB2  1 
ATOM   4595 H  HB3  . MET A 1 321 ? 9.84031   6.09554   -24.83266 1.000 26.94238  ? 301 MET A HB3  1 
ATOM   4596 H  HG2  . MET A 1 321 ? 7.76901   4.94302   -24.41546 1.000 27.17629  ? 301 MET A HG2  1 
ATOM   4597 H  HG3  . MET A 1 321 ? 7.05070   6.35974   -24.46418 1.000 27.17629  ? 301 MET A HG3  1 
ATOM   4598 H  HE1  . MET A 1 321 ? 8.84521   4.29979   -27.94334 1.000 28.86033  ? 301 MET A HE1  1 
ATOM   4599 H  HE2  . MET A 1 321 ? 9.71329   4.74672   -26.69027 1.000 28.86033  ? 301 MET A HE2  1 
ATOM   4600 H  HE3  . MET A 1 321 ? 8.61313   3.61201   -26.53033 1.000 28.86033  ? 301 MET A HE3  1 
ATOM   4601 N  N    . MET A 1 322 ? 8.74204   4.29019   -21.85261 1.000 18.83284  ? 302 MET A N    1 
ATOM   4602 C  CA   . MET A 1 322 ? 8.93886   2.88188   -21.59339 1.000 18.00907  ? 302 MET A CA   1 
ATOM   4603 C  C    . MET A 1 322 ? 8.58753   2.01626   -22.81645 1.000 21.51763  ? 302 MET A C    1 
ATOM   4604 O  O    . MET A 1 322 ? 7.69721   2.34595   -23.59294 1.000 21.23433  ? 302 MET A O    1 
ATOM   4605 C  CB   . MET A 1 322 ? 8.19610   2.28423   -20.40491 1.000 21.72217  ? 302 MET A CB   1 
ATOM   4606 C  CG   . MET A 1 322 ? 8.51406   2.91639   -19.08834 1.000 27.71333  ? 302 MET A CG   1 
ATOM   4607 S  SD   . MET A 1 322 ? 7.51141   2.05073   -17.82694 1.000 25.86747  ? 302 MET A SD   1 
ATOM   4608 C  CE   . MET A 1 322 ? 8.59450   2.19234   -16.45494 1.000 27.64341  ? 302 MET A CE   1 
ATOM   4609 H  H    . MET A 1 322 ? 7.99528   4.61702   -21.57852 1.000 22.62317  ? 302 MET A H    1 
ATOM   4610 H  HA   . MET A 1 322 ? 9.88085   2.84729   -21.36458 1.000 21.63464  ? 302 MET A HA   1 
ATOM   4611 H  HB2  . MET A 1 322 ? 7.24305   2.38485   -20.55481 1.000 26.09036  ? 302 MET A HB2  1 
ATOM   4612 H  HB3  . MET A 1 322 ? 8.42427   1.34367   -20.34015 1.000 26.09036  ? 302 MET A HB3  1 
ATOM   4613 H  HG2  . MET A 1 322 ? 9.45601   2.81191   -18.88164 1.000 33.27976  ? 302 MET A HG2  1 
ATOM   4614 H  HG3  . MET A 1 322 ? 8.27925   3.85747   -19.09947 1.000 33.27976  ? 302 MET A HG3  1 
ATOM   4615 H  HE1  . MET A 1 322 ? 8.17670   1.78606   -15.67952 1.000 33.19586  ? 302 MET A HE1  1 
ATOM   4616 H  HE2  . MET A 1 322 ? 9.42545   1.73592   -16.66014 1.000 33.19586  ? 302 MET A HE2  1 
ATOM   4617 H  HE3  . MET A 1 322 ? 8.76648   3.13154   -16.28397 1.000 33.19586  ? 302 MET A HE3  1 
ATOM   4618 N  N    . LEU A 1 323 ? 9.35544   0.94706   -23.03209 1.000 17.86219  ? 303 LEU A N    1 
ATOM   4619 C  CA   . LEU A 1 323 ? 8.97410   -0.13277  -23.92966 1.000 19.41120  ? 303 LEU A CA   1 
ATOM   4620 C  C    . LEU A 1 323 ? 8.32957   -1.24071  -23.09703 1.000 20.04601  ? 303 LEU A C    1 
ATOM   4621 O  O    . LEU A 1 323 ? 9.01036   -1.84846  -22.25909 1.000 19.00294  ? 303 LEU A O    1 
ATOM   4622 C  CB   . LEU A 1 323 ? 10.19504  -0.68232  -24.66393 1.000 19.30599  ? 303 LEU A CB   1 
ATOM   4623 C  CG   . LEU A 1 323 ? 11.08750  0.32116   -25.37722 1.000 18.46062  ? 303 LEU A CG   1 
ATOM   4624 C  CD1  . LEU A 1 323 ? 12.30908  -0.38449  -25.89657 1.000 21.77139  ? 303 LEU A CD1  1 
ATOM   4625 C  CD2  . LEU A 1 323 ? 10.29667  0.97803   -26.49925 1.000 20.44633  ? 303 LEU A CD2  1 
ATOM   4626 H  H    . LEU A 1 323 ? 10.12038  0.82584   -22.65822 1.000 21.45838  ? 303 LEU A H    1 
ATOM   4627 H  HA   . LEU A 1 323 ? 8.33478   0.20169   -24.57797 1.000 23.31721  ? 303 LEU A HA   1 
ATOM   4628 H  HB2  . LEU A 1 323 ? 10.75038  -1.14231  -24.01517 1.000 23.19095  ? 303 LEU A HB2  1 
ATOM   4629 H  HB3  . LEU A 1 323 ? 9.88167   -1.30820  -25.33548 1.000 23.19095  ? 303 LEU A HB3  1 
ATOM   4630 H  HG   . LEU A 1 323 ? 11.38494  1.01963   -24.77342 1.000 22.17651  ? 303 LEU A HG   1 
ATOM   4631 H  HD11 . LEU A 1 323 ? 12.88738  0.26267   -26.32977 1.000 26.14943  ? 303 LEU A HD11 1 
ATOM   4632 H  HD12 . LEU A 1 323 ? 12.77458  -0.79860  -25.15312 1.000 26.14943  ? 303 LEU A HD12 1 
ATOM   4633 H  HD13 . LEU A 1 323 ? 12.03514  -1.06226  -26.53414 1.000 26.14943  ? 303 LEU A HD13 1 
ATOM   4634 H  HD21 . LEU A 1 323 ? 10.88651  1.56165   -27.00162 1.000 24.55935  ? 303 LEU A HD21 1 
ATOM   4635 H  HD22 . LEU A 1 323 ? 9.94046   0.28796   -27.08048 1.000 24.55935  ? 303 LEU A HD22 1 
ATOM   4636 H  HD23 . LEU A 1 323 ? 9.57072   1.49340   -26.11418 1.000 24.55935  ? 303 LEU A HD23 1 
ATOM   4637 N  N    . LEU A 1 324 ? 7.02610   -1.49103  -23.29359 1.000 18.11114  ? 304 LEU A N    1 
ATOM   4638 C  CA   . LEU A 1 324 ? 6.29532   -2.45423  -22.47069 1.000 17.27171  ? 304 LEU A CA   1 
ATOM   4639 C  C    . LEU A 1 324 ? 6.34817   -3.83080  -23.11829 1.000 17.40215  ? 304 LEU A C    1 
ATOM   4640 O  O    . LEU A 1 324 ? 5.50496   -4.20164  -23.91760 1.000 18.20260  ? 304 LEU A O    1 
ATOM   4641 C  CB   . LEU A 1 324 ? 4.85276   -1.98616  -22.23028 1.000 19.65779  ? 304 LEU A CB   1 
ATOM   4642 C  CG   . LEU A 1 324 ? 4.68103   -0.65626  -21.49896 1.000 17.51429  ? 304 LEU A CG   1 
ATOM   4643 C  CD1  . LEU A 1 324 ? 3.16651   -0.33127  -21.52033 1.000 20.52240  ? 304 LEU A CD1  1 
ATOM   4644 C  CD2  . LEU A 1 324 ? 5.18414   -0.78563  -20.09347 1.000 21.10713  ? 304 LEU A CD2  1 
ATOM   4645 H  H    . LEU A 1 324 ? 6.54689   -1.11268  -23.89923 1.000 21.75713  ? 304 LEU A H    1 
ATOM   4646 H  HA   . LEU A 1 324 ? 6.74656   -2.52287  -21.61479 1.000 20.74982  ? 304 LEU A HA   1 
ATOM   4647 H  HB2  . LEU A 1 324 ? 4.41865   -1.89526  -23.09294 1.000 23.61311  ? 304 LEU A HB2  1 
ATOM   4648 H  HB3  . LEU A 1 324 ? 4.40154   -2.66265  -21.70146 1.000 23.61311  ? 304 LEU A HB3  1 
ATOM   4649 H  HG   . LEU A 1 324 ? 5.18237   0.06124   -21.91698 1.000 21.04091  ? 304 LEU A HG   1 
ATOM   4650 H  HD11 . LEU A 1 324 ? 3.01466   0.49797   -21.04055 1.000 24.65064  ? 304 LEU A HD11 1 
ATOM   4651 H  HD12 . LEU A 1 324 ? 2.87639   -0.23849  -22.44127 1.000 24.65064  ? 304 LEU A HD12 1 
ATOM   4652 H  HD13 . LEU A 1 324 ? 2.68225   -1.05455  -21.09225 1.000 24.65064  ? 304 LEU A HD13 1 
ATOM   4653 H  HD21 . LEU A 1 324 ? 4.92411   0.00240   -19.59117 1.000 25.35232  ? 304 LEU A HD21 1 
ATOM   4654 H  HD22 . LEU A 1 324 ? 4.79551   -1.57782  -19.69059 1.000 25.35232  ? 304 LEU A HD22 1 
ATOM   4655 H  HD23 . LEU A 1 324 ? 6.15088   -0.86327  -20.10998 1.000 25.35232  ? 304 LEU A HD23 1 
ATOM   4656 N  N    . PHE A 1 325 ? 7.37250   -4.60566  -22.76864 1.000 17.04676  ? 305 PHE A N    1 
ATOM   4657 C  CA   . PHE A 1 325 ? 7.59273   -5.87930  -23.47619 1.000 16.54828  ? 305 PHE A CA   1 
ATOM   4658 C  C    . PHE A 1 325 ? 6.48546   -6.90217  -23.21380 1.000 16.24847  ? 305 PHE A C    1 
ATOM   4659 O  O    . PHE A 1 325 ? 6.13039   -7.66283  -24.13172 1.000 17.93278  ? 305 PHE A O    1 
ATOM   4660 C  CB   . PHE A 1 325 ? 8.94270   -6.47963  -23.08651 1.000 18.42965  ? 305 PHE A CB   1 
ATOM   4661 C  CG   . PHE A 1 325 ? 10.12635  -5.61583  -23.47457 1.000 17.98041  ? 305 PHE A CG   1 
ATOM   4662 C  CD1  . PHE A 1 325 ? 10.37335  -5.27710  -24.81019 1.000 16.94953  ? 305 PHE A CD1  1 
ATOM   4663 C  CD2  . PHE A 1 325 ? 11.01122  -5.16454  -22.51339 1.000 18.66223  ? 305 PHE A CD2  1 
ATOM   4664 C  CE1  . PHE A 1 325 ? 11.46777  -4.46994  -25.15480 1.000 18.93808  ? 305 PHE A CE1  1 
ATOM   4665 C  CE2  . PHE A 1 325 ? 12.11830  -4.35291  -22.87761 1.000 19.21789  ? 305 PHE A CE2  1 
ATOM   4666 C  CZ   . PHE A 1 325 ? 12.31285  -4.00484  -24.18573 1.000 18.89057  ? 305 PHE A CZ   1 
ATOM   4667 H  H    . PHE A 1 325 ? 7.93989   -4.42938  -22.14687 1.000 20.47987  ? 305 PHE A H    1 
ATOM   4668 H  HA   . PHE A 1 325 ? 7.59562   -5.68052  -24.42560 1.000 19.88170  ? 305 PHE A HA   1 
ATOM   4669 H  HB2  . PHE A 1 325 ? 8.96543   -6.59896  -22.12414 1.000 22.13934  ? 305 PHE A HB2  1 
ATOM   4670 H  HB3  . PHE A 1 325 ? 9.04304   -7.33669  -23.52954 1.000 22.13934  ? 305 PHE A HB3  1 
ATOM   4671 H  HD1  . PHE A 1 325 ? 9.80549   -5.59071  -25.47659 1.000 20.36319  ? 305 PHE A HD1  1 
ATOM   4672 H  HD2  . PHE A 1 325 ? 10.88069  -5.39406  -21.62166 1.000 22.41844  ? 305 PHE A HD2  1 
ATOM   4673 H  HE1  . PHE A 1 325 ? 11.61908  -4.25036  -26.04575 1.000 22.74945  ? 305 PHE A HE1  1 
ATOM   4674 H  HE2  . PHE A 1 325 ? 12.71193  -4.05765  -22.22544 1.000 23.08522  ? 305 PHE A HE2  1 
ATOM   4675 H  HZ   . PHE A 1 325 ? 13.02238  -3.44988  -24.41699 1.000 22.69244  ? 305 PHE A HZ   1 
ATOM   4676 N  N    . GLU A 1 326 ? 5.97184   -6.99074  -21.97723 1.000 16.67838  ? 306 GLU A N    1 
ATOM   4677 C  CA   . GLU A 1 326 ? 4.86182   -7.91500  -21.73683 1.000 18.86822  ? 306 GLU A CA   1 
ATOM   4678 C  C    . GLU A 1 326 ? 3.62461   -7.50479  -22.55153 1.000 18.60228  ? 306 GLU A C    1 
ATOM   4679 O  O    . GLU A 1 326 ? 2.94802   -8.35079  -23.14936 1.000 17.73088  ? 306 GLU A O    1 
ATOM   4680 C  CB   . GLU A 1 326 ? 4.50415   -8.03032  -20.25060 1.000 18.47739  ? 306 GLU A CB   1 
ATOM   4681 C  CG   . GLU A 1 326 ? 3.50129   -9.18606  -19.97312 1.000 19.48604  ? 306 GLU A CG   1 
ATOM   4682 C  CD   . GLU A 1 326 ? 3.10213   -9.31695  -18.52405 1.000 23.61713  ? 306 GLU A CD   1 
ATOM   4683 O  OE1  . GLU A 1 326 ? 3.85070   -8.82138  -17.64545 1.000 21.50415  ? 306 GLU A OE1  1 
ATOM   4684 O  OE2  . GLU A 1 326 ? 2.00268   -9.87190  -18.24780 1.000 25.46128  ? 306 GLU A OE2  1 
ATOM   4685 H  H    . GLU A 1 326 ? 6.23833   -6.54492  -21.29179 1.000 20.03781  ? 306 GLU A H    1 
ATOM   4686 H  HA   . GLU A 1 326 ? 5.15528   -8.79646  -22.01578 1.000 22.66562  ? 306 GLU A HA   1 
ATOM   4687 H  HB2  . GLU A 1 326 ? 5.31204   -8.20243  -19.74209 1.000 22.19663  ? 306 GLU A HB2  1 
ATOM   4688 H  HB3  . GLU A 1 326 ? 4.09762   -7.20014  -19.95659 1.000 22.19663  ? 306 GLU A HB3  1 
ATOM   4689 H  HG2  . GLU A 1 326 ? 2.69444   -9.02854  -20.48799 1.000 23.40701  ? 306 GLU A HG2  1 
ATOM   4690 H  HG3  . GLU A 1 326 ? 3.90902   -10.02371 -20.24332 1.000 23.40701  ? 306 GLU A HG3  1 
ATOM   4691 N  N    . SER A 1 327 ? 3.29718   -6.21334  -22.59025 1.000 16.91450  ? 307 SER A N    1 
ATOM   4692 C  CA   . SER A 1 327 ? 2.18084   -5.76450  -23.42113 1.000 19.14686  ? 307 SER A CA   1 
ATOM   4693 C  C    . SER A 1 327 ? 2.35897   -6.16292  -24.88030 1.000 19.37350  ? 307 SER A C    1 
ATOM   4694 O  O    . SER A 1 327 ? 1.40594   -6.64798  -25.51869 1.000 19.05155  ? 307 SER A O    1 
ATOM   4695 C  CB   . SER A 1 327 ? 1.99240   -4.25234  -23.27270 1.000 17.27282  ? 307 SER A CB   1 
ATOM   4696 O  OG   . SER A 1 327 ? 0.83016   -3.80658  -23.98626 1.000 19.04892  ? 307 SER A OG   1 
ATOM   4697 H  H    . SER A 1 327 ? 3.69673   -5.58903  -22.15414 1.000 20.32117  ? 307 SER A H    1 
ATOM   4698 H  HA   . SER A 1 327 ? 1.37148   -6.19771  -23.10782 1.000 22.99999  ? 307 SER A HA   1 
ATOM   4699 H  HB2  . SER A 1 327 ? 1.88610   -4.03880  -22.33249 1.000 20.75114  ? 307 SER A HB2  1 
ATOM   4700 H  HB3  . SER A 1 327 ? 2.77345   -3.80093  -23.62920 1.000 20.75114  ? 307 SER A HB3  1 
ATOM   4701 H  HG   . SER A 1 327 ? 0.90788   -3.98667  -24.80304 1.000 22.88247  ? 307 SER A HG   1 
ATOM   4702 N  N    . ALA A 1 328 ? 3.56020   -5.92735  -25.45194 1.000 16.05868  ? 308 ALA A N    1 
ATOM   4703 C  CA   . ALA A 1 328 ? 3.83897   -6.36642  -26.82102 1.000 17.89324  ? 308 ALA A CA   1 
ATOM   4704 C  C    . ALA A 1 328 ? 3.64887   -7.86671  -27.01114 1.000 17.38594  ? 308 ALA A C    1 
ATOM   4705 O  O    . ALA A 1 328 ? 3.15683   -8.30936  -28.06148 1.000 18.04022  ? 308 ALA A O    1 
ATOM   4706 C  CB   . ALA A 1 328 ? 5.25995   -5.96034  -27.21488 1.000 19.68926  ? 308 ALA A CB   1 
ATOM   4707 H  H    . ALA A 1 328 ? 4.21476   -5.52171  -25.06904 1.000 19.29417  ? 308 ALA A H    1 
ATOM   4708 H  HA   . ALA A 1 328 ? 3.20746   -5.92269  -27.40856 1.000 21.49565  ? 308 ALA A HA   1 
ATOM   4709 H  HB1  . ALA A 1 328 ? 5.44782   -6.29309  -28.10645 1.000 23.65087  ? 308 ALA A HB1  1 
ATOM   4710 H  HB2  . ALA A 1 328 ? 5.32691   -4.99274  -27.20201 1.000 23.65087  ? 308 ALA A HB2  1 
ATOM   4711 H  HB3  . ALA A 1 328 ? 5.88533   -6.34366  -26.58017 1.000 23.65087  ? 308 ALA A HB3  1 
ATOM   4712 N  N    . ASN A 1 329 ? 4.10202   -8.65496  -26.02997 1.000 17.19606  ? 309 ASN A N    1 
ATOM   4713 C  CA   . ASN A 1 329 ? 3.99453   -10.09817 -26.11550 1.000 16.91124  ? 309 ASN A CA   1 
ATOM   4714 C  C    . ASN A 1 329 ? 2.55827   -10.61103 -26.07078 1.000 17.34055  ? 309 ASN A C    1 
ATOM   4715 O  O    . ASN A 1 329 ? 2.34042   -11.79635 -26.37278 1.000 17.77153  ? 309 ASN A O    1 
ATOM   4716 C  CB   . ASN A 1 329 ? 4.78690   -10.72883 -24.99795 1.000 16.36043  ? 309 ASN A CB   1 
ATOM   4717 C  CG   . ASN A 1 329 ? 6.27515   -10.73174 -25.28866 1.000 17.02858  ? 309 ASN A CG   1 
ATOM   4718 O  OD1  . ASN A 1 329 ? 6.72527   -10.23682 -26.35872 1.000 17.90027  ? 309 ASN A OD1  1 
ATOM   4719 N  ND2  . ASN A 1 329 ? 7.04940   -11.29976 -24.34595 1.000 18.70895  ? 309 ASN A ND2  1 
ATOM   4720 H  H    . ASN A 1 329 ? 4.47404   -8.37074  -25.30857 1.000 20.65904  ? 309 ASN A H    1 
ATOM   4721 H  HA   . ASN A 1 329 ? 4.37102   -10.37903 -26.96419 1.000 20.31725  ? 309 ASN A HA   1 
ATOM   4722 H  HB2  . ASN A 1 329 ? 4.63870   -10.22875 -24.18011 1.000 19.65628  ? 309 ASN A HB2  1 
ATOM   4723 H  HB3  . ASN A 1 329 ? 4.49887   -11.64776 -24.88173 1.000 19.65628  ? 309 ASN A HB3  1 
ATOM   4724 H  HD21 . ASN A 1 329 ? 7.90216   -11.33261 -24.45232 1.000 22.47451  ? 309 ASN A HD21 1 
ATOM   4725 H  HD22 . ASN A 1 329 ? 6.69145   -11.62993 -23.63711 1.000 22.47451  ? 309 ASN A HD22 1 
ATOM   4726 N  N    . PHE A 1 330 ? 1.59485   -9.77530  -25.66100 1.000 18.15640  ? 310 PHE A N    1 
ATOM   4727 C  CA   . PHE A 1 330 ? 0.17241   -10.11869 -25.64526 1.000 19.26227  ? 310 PHE A CA   1 
ATOM   4728 C  C    . PHE A 1 330 ? -0.63956  -9.31261  -26.66193 1.000 22.14189  ? 310 PHE A C    1 
ATOM   4729 O  O    . PHE A 1 330 ? -1.87694  -9.23767  -26.57285 1.000 21.01071  ? 310 PHE A O    1 
ATOM   4730 C  CB   . PHE A 1 330 ? -0.36318  -9.97599  -24.22685 1.000 20.44270  ? 310 PHE A CB   1 
ATOM   4731 C  CG   . PHE A 1 330 ? 0.04628   -11.13029 -23.32554 1.000 18.04805  ? 310 PHE A CG   1 
ATOM   4732 C  CD1  . PHE A 1 330 ? 1.30589   -11.14102 -22.75907 1.000 19.89508  ? 310 PHE A CD1  1 
ATOM   4733 C  CD2  . PHE A 1 330 ? -0.78768  -12.24593 -23.13430 1.000 19.92782  ? 310 PHE A CD2  1 
ATOM   4734 C  CE1  . PHE A 1 330 ? 1.74229   -12.17752 -21.96278 1.000 19.96102  ? 310 PHE A CE1  1 
ATOM   4735 C  CE2  . PHE A 1 330 ? -0.36611  -13.29982 -22.33557 1.000 21.35430  ? 310 PHE A CE2  1 
ATOM   4736 C  CZ   . PHE A 1 330 ? 0.90521   -13.27755 -21.73820 1.000 21.81453  ? 310 PHE A CZ   1 
ATOM   4737 H  H    . PHE A 1 330 ? 1.74888   -8.97771  -25.37863 1.000 21.81145  ? 310 PHE A H    1 
ATOM   4738 H  HA   . PHE A 1 330 ? 0.05842   -11.04680 -25.90316 1.000 23.13849  ? 310 PHE A HA   1 
ATOM   4739 H  HB2  . PHE A 1 330 ? -0.01855  -9.15591  -23.84007 1.000 24.55500  ? 310 PHE A HB2  1 
ATOM   4740 H  HB3  . PHE A 1 330 ? -1.33230  -9.94713  -24.25655 1.000 24.55500  ? 310 PHE A HB3  1 
ATOM   4741 H  HD1  . PHE A 1 330 ? 1.87793   -10.42569 -22.92023 1.000 23.89785  ? 310 PHE A HD1  1 
ATOM   4742 H  HD2  . PHE A 1 330 ? -1.62233  -12.27776 -23.54327 1.000 23.93714  ? 310 PHE A HD2  1 
ATOM   4743 H  HE1  . PHE A 1 330 ? 2.58782   -12.14672 -21.57673 1.000 23.97699  ? 310 PHE A HE1  1 
ATOM   4744 H  HE2  . PHE A 1 330 ? -0.92950  -14.02622 -22.19476 1.000 25.64892  ? 310 PHE A HE2  1 
ATOM   4745 H  HZ   . PHE A 1 330 ? 1.18679   -13.98293 -21.20150 1.000 26.20119  ? 310 PHE A HZ   1 
ATOM   4746 N  N    . ASP A 1 331 ? 0.03184   -8.81609  -27.68844 1.000 19.26771  ? 311 ASP A N    1 
ATOM   4747 C  CA   . ASP A 1 331 ? -0.60201  -7.97629  -28.68997 1.000 18.77557  ? 311 ASP A CA   1 
ATOM   4748 C  C    . ASP A 1 331 ? -1.29020  -8.85150  -29.72205 1.000 22.51096  ? 311 ASP A C    1 
ATOM   4749 O  O    . ASP A 1 331 ? -0.62484  -9.56652  -30.47877 1.000 21.70440  ? 311 ASP A O    1 
ATOM   4750 C  CB   . ASP A 1 331 ? 0.44164   -7.05836  -29.32038 1.000 21.65454  ? 311 ASP A CB   1 
ATOM   4751 C  CG   . ASP A 1 331 ? -0.15290  -6.01163  -30.25796 1.000 24.67178  ? 311 ASP A CG   1 
ATOM   4752 O  OD1  . ASP A 1 331 ? -1.29545  -6.17022  -30.77884 1.000 25.44624  ? 311 ASP A OD1  1 
ATOM   4753 O  OD2  . ASP A 1 331 ? 0.58460   -5.04510  -30.53682 1.000 21.32849  ? 311 ASP A OD2  1 
ATOM   4754 H  H    . ASP A 1 331 ? 0.86904   -8.95331  -27.82939 1.000 23.14502  ? 311 ASP A H    1 
ATOM   4755 H  HA   . ASP A 1 331 ? -1.28647  -7.42640  -28.27762 1.000 22.55444  ? 311 ASP A HA   1 
ATOM   4756 H  HB2  . ASP A 1 331 ? 0.91374   -6.58989  -28.61429 1.000 26.00920  ? 311 ASP A HB2  1 
ATOM   4757 H  HB3  . ASP A 1 331 ? 1.06322   -7.59753  -29.83402 1.000 26.00920  ? 311 ASP A HB3  1 
ATOM   4758 N  N    . GLU A 1 332 ? -2.62771  -8.76688  -29.76296 1.000 24.35088  ? 312 GLU A N    1 
ATOM   4759 C  CA   . GLU A 1 332 ? -3.41317  -9.57414  -30.67143 1.000 27.97292  ? 312 GLU A CA   1 
ATOM   4760 C  C    . GLU A 1 332 ? -3.13369  -9.26749  -32.14212 1.000 31.80065  ? 312 GLU A C    1 
ATOM   4761 O  O    . GLU A 1 332 ? -3.48143  -10.07797 -33.00200 1.000 32.81183  ? 312 GLU A O    1 
ATOM   4762 C  CB   . GLU A 1 332 ? -4.92215  -9.39726  -30.35518 1.000 30.82154  ? 312 GLU A CB   1 
ATOM   4763 C  CG   . GLU A 1 332 ? -5.39767  -7.93139  -30.14555 1.000 49.89433  ? 312 GLU A CG   1 
ATOM   4764 C  CD   . GLU A 1 332 ? -4.77974  -7.25490  -28.90233 1.000 53.64658  ? 312 GLU A CD   1 
ATOM   4765 O  OE1  . GLU A 1 332 ? -4.74393  -7.91260  -27.85179 1.000 51.40500  ? 312 GLU A OE1  1 
ATOM   4766 O  OE2  . GLU A 1 332 ? -4.19284  -6.13905  -28.95702 1.000 37.28163  ? 312 GLU A OE2  1 
ATOM   4767 H  H    . GLU A 1 332 ? -3.09703  -8.24340  -29.26768 1.000 29.24482  ? 312 GLU A H    1 
ATOM   4768 H  HA   . GLU A 1 332 ? -3.18238  -10.50612 -30.53345 1.000 33.59126  ? 312 GLU A HA   1 
ATOM   4769 H  HB2  . GLU A 1 332 ? -5.43314  -9.76315  -31.09404 1.000 37.00960  ? 312 GLU A HB2  1 
ATOM   4770 H  HB3  . GLU A 1 332 ? -5.12173  -9.88431  -29.54042 1.000 37.00960  ? 312 GLU A HB3  1 
ATOM   4771 H  HG2  . GLU A 1 332 ? -5.14895  -7.40726  -30.92294 1.000 59.89696  ? 312 GLU A HG2  1 
ATOM   4772 H  HG3  . GLU A 1 332 ? -6.36159  -7.92730  -30.03724 1.000 59.89696  ? 312 GLU A HG3  1 
ATOM   4773 N  N    . ALA A 1 333 ? -2.50568  -8.14012  -32.46281 1.000 27.38918  ? 313 ALA A N    1 
ATOM   4774 C  CA   . ALA A 1 333 ? -2.10645  -7.88219  -33.84142 1.000 28.59689  ? 313 ALA A CA   1 
ATOM   4775 C  C    . ALA A 1 333 ? -1.04729  -8.86128  -34.34622 1.000 31.81005  ? 313 ALA A C    1 
ATOM   4776 O  O    . ALA A 1 333 ? -0.93632  -9.07039  -35.56239 1.000 31.90798  ? 313 ALA A O    1 
ATOM   4777 C  CB   . ALA A 1 333 ? -1.59483  -6.44098  -33.96876 1.000 32.87699  ? 313 ALA A CB   1 
ATOM   4778 H  H    . ALA A 1 333 ? -2.30131  -7.51576  -31.90782 1.000 32.89078  ? 313 ALA A H    1 
ATOM   4779 H  HA   . ALA A 1 333 ? -2.88445  -7.98311  -34.41189 1.000 34.34003  ? 313 ALA A HA   1 
ATOM   4780 H  HB1  . ALA A 1 333 ? -1.31632  -6.28450  -34.88465 1.000 39.47615  ? 313 ALA A HB1  1 
ATOM   4781 H  HB2  . ALA A 1 333 ? -2.30982  -5.82993  -33.73146 1.000 39.47615  ? 313 ALA A HB2  1 
ATOM   4782 H  HB3  . ALA A 1 333 ? -0.84250  -6.31877  -33.36879 1.000 39.47615  ? 313 ALA A HB3  1 
ATOM   4783 N  N    . VAL A 1 334 ? -0.28456  -9.45792  -33.44052 1.000 25.48687  ? 314 VAL A N    1 
ATOM   4784 C  CA   . VAL A 1 334 ? 0.82649   -10.33343 -33.76873 1.000 23.51155  ? 314 VAL A CA   1 
ATOM   4785 C  C    . VAL A 1 334 ? 0.55617   -11.76130 -33.32939 1.000 25.84241  ? 314 VAL A C    1 
ATOM   4786 O  O    . VAL A 1 334 ? 0.88301   -12.70283 -34.05584 1.000 29.75178  ? 314 VAL A O    1 
ATOM   4787 C  CB   . VAL A 1 334 ? 2.14123   -9.81008  -33.13452 1.000 25.41494  ? 314 VAL A CB   1 
ATOM   4788 C  CG1  . VAL A 1 334 ? 3.27598   -10.81082 -33.28428 1.000 26.54656  ? 314 VAL A CG1  1 
ATOM   4789 C  CG2  . VAL A 1 334 ? 2.49601   -8.46008  -33.75510 1.000 29.29973  ? 314 VAL A CG2  1 
ATOM   4790 H  H    . VAL A 1 334 ? -0.39721  -9.36598  -32.59290 1.000 30.60801  ? 314 VAL A H    1 
ATOM   4791 H  HA   . VAL A 1 334 ? 0.93879   -10.34280 -34.73216 1.000 28.23762  ? 314 VAL A HA   1 
ATOM   4792 H  HB   . VAL A 1 334 ? 2.01115   -9.69118  -32.18066 1.000 30.52170  ? 314 VAL A HB   1 
ATOM   4793 H  HG11 . VAL A 1 334 ? 4.11713   -10.36446 -33.09949 1.000 31.87964  ? 314 VAL A HG11 1 
ATOM   4794 H  HG12 . VAL A 1 334 ? 3.14171   -11.53699 -32.65536 1.000 31.87964  ? 314 VAL A HG12 1 
ATOM   4795 H  HG13 . VAL A 1 334 ? 3.27623   -11.15459 -34.19132 1.000 31.87964  ? 314 VAL A HG13 1 
ATOM   4796 H  HG21 . VAL A 1 334 ? 3.42327   -8.25541  -33.55710 1.000 35.18344  ? 314 VAL A HG21 1 
ATOM   4797 H  HG22 . VAL A 1 334 ? 2.36594   -8.50984  -34.71505 1.000 35.18344  ? 314 VAL A HG22 1 
ATOM   4798 H  HG23 . VAL A 1 334 ? 1.91885   -7.77773  -33.37802 1.000 35.18344  ? 314 VAL A HG23 1 
ATOM   4799 N  N    . PHE A 1 335 ? -0.00172  -11.93924 -32.13649 1.000 24.20713  ? 315 PHE A N    1 
ATOM   4800 C  CA   . PHE A 1 335 ? -0.16609  -13.23978 -31.50322 1.000 24.23820  ? 315 PHE A CA   1 
ATOM   4801 C  C    . PHE A 1 335 ? -1.65220  -13.57314 -31.44349 1.000 26.69086  ? 315 PHE A C    1 
ATOM   4802 O  O    . PHE A 1 335 ? -2.40433  -12.94043 -30.69755 1.000 29.37815  ? 315 PHE A O    1 
ATOM   4803 C  CB   . PHE A 1 335 ? 0.44757   -13.26413 -30.10675 1.000 22.99860  ? 315 PHE A CB   1 
ATOM   4804 C  CG   . PHE A 1 335 ? 1.89864   -12.95570 -30.09357 1.000 20.28326  ? 315 PHE A CG   1 
ATOM   4805 C  CD1  . PHE A 1 335 ? 2.82235   -13.91397 -30.45184 1.000 24.20680  ? 315 PHE A CD1  1 
ATOM   4806 C  CD2  . PHE A 1 335 ? 2.36328   -11.67712 -29.75252 1.000 22.15703  ? 315 PHE A CD2  1 
ATOM   4807 C  CE1  . PHE A 1 335 ? 4.17776   -13.61926 -30.48157 1.000 22.59806  ? 315 PHE A CE1  1 
ATOM   4808 C  CE2  . PHE A 1 335 ? 3.70888   -11.38105 -29.75916 1.000 21.53296  ? 315 PHE A CE2  1 
ATOM   4809 C  CZ   . PHE A 1 335 ? 4.62880   -12.35619 -30.12362 1.000 21.04088  ? 315 PHE A CZ   1 
ATOM   4810 H  H    . PHE A 1 335 ? -0.30480  -11.29355 -31.65605 1.000 29.07232  ? 315 PHE A H    1 
ATOM   4811 H  HA   . PHE A 1 335 ? 0.28120   -13.90633 -32.04777 1.000 29.10960  ? 315 PHE A HA   1 
ATOM   4812 H  HB2  . PHE A 1 335 ? -0.00166  -12.60408 -29.55590 1.000 27.62208  ? 315 PHE A HB2  1 
ATOM   4813 H  HB3  . PHE A 1 335 ? 0.32830   -14.14907 -29.72785 1.000 27.62208  ? 315 PHE A HB3  1 
ATOM   4814 H  HD1  . PHE A 1 335 ? 2.53337   -14.76891 -30.67650 1.000 29.07193  ? 315 PHE A HD1  1 
ATOM   4815 H  HD2  . PHE A 1 335 ? 1.75184   -11.01694 -29.51755 1.000 26.61220  ? 315 PHE A HD2  1 
ATOM   4816 H  HE1  . PHE A 1 335 ? 4.78731   -14.27132 -30.74266 1.000 27.14144  ? 315 PHE A HE1  1 
ATOM   4817 H  HE2  . PHE A 1 335 ? 4.00049   -10.53085 -29.52034 1.000 25.86332  ? 315 PHE A HE2  1 
ATOM   4818 H  HZ   . PHE A 1 335 ? 5.53881   -12.16445 -30.12776 1.000 25.27281  ? 315 PHE A HZ   1 
ATOM   4819 N  N    . CYS A 1 336 ? -2.06811  -14.58192 -32.18860 1.000 24.51883  ? 316 CYS A N    1 
ATOM   4820 C  CA   . CYS A 1 336 ? -3.46287  -15.00543 -32.14669 1.000 27.05298  ? 316 CYS A CA   1 
ATOM   4821 C  C    . CYS A 1 336 ? -3.79154  -15.59228 -30.77979 1.000 26.02841  ? 316 CYS A C    1 
ATOM   4822 O  O    . CYS A 1 336 ? -3.06916  -16.45504 -30.26542 1.000 22.82294  ? 316 CYS A O    1 
ATOM   4823 C  CB   . CYS A 1 336 ? -3.71128  -16.03202 -33.25301 1.000 27.19501  ? 316 CYS A CB   1 
ATOM   4824 S  SG   . CYS A 1 336 ? -5.40394  -16.62007 -33.36884 1.000 34.69608  ? 316 CYS A SG   1 
ATOM   4825 H  H    . CYS A 1 336 ? -1.57073  -15.03623 -32.72322 1.000 29.44636  ? 316 CYS A H    1 
ATOM   4826 H  HA   . CYS A 1 336 ? -4.04978  -14.24692 -32.29194 1.000 32.48734  ? 316 CYS A HA   1 
ATOM   4827 H  HB2  . CYS A 1 336 ? -3.48407  -15.62740 -34.10481 1.000 32.65778  ? 316 CYS A HB2  1 
ATOM   4828 H  HB3  . CYS A 1 336 ? -3.14518  -16.80270 -33.09030 1.000 32.65778  ? 316 CYS A HB3  1 
ATOM   4829 H  HG   . CYS A 1 336 ? -5.44541  -17.54279 -34.13493 1.000 41.65905  ? 316 CYS A HG   1 
ATOM   4830 N  N    . GLU A 1 337 ? -4.92805  -15.17059 -30.21119 1.000 24.90646  ? 317 GLU A N    1 
ATOM   4831 C  CA   . GLU A 1 337 ? -5.37959  -15.61690 -28.89884 1.000 25.05214  ? 317 GLU A CA   1 
ATOM   4832 C  C    . GLU A 1 337 ? -4.23338  -15.57137 -27.87788 1.000 24.51528  ? 317 GLU A C    1 
ATOM   4833 O  O    . GLU A 1 337 ? -3.80072  -16.58738 -27.36396 1.000 23.81983  ? 317 GLU A O    1 
ATOM   4834 C  CB   . GLU A 1 337 ? -5.99249  -17.01073 -28.95811 1.000 27.81689  ? 317 GLU A CB   1 
ATOM   4835 C  CG   . GLU A 1 337 ? -7.29799  -17.04703 -29.70481 1.000 33.25463  ? 317 GLU A CG   1 
ATOM   4836 C  CD   . GLU A 1 337 ? -8.12737  -18.24315 -29.27670 1.000 44.68183  ? 317 GLU A CD   1 
ATOM   4837 O  OE1  . GLU A 1 337 ? -7.59464  -19.36102 -29.41541 1.000 35.01044  ? 317 GLU A OE1  1 
ATOM   4838 O  OE2  . GLU A 1 337 ? -9.29383  -18.06699 -28.86360 1.000 55.75272  ? 317 GLU A OE2  1 
ATOM   4839 H  H    . GLU A 1 337 ? -5.46535  -14.61025 -30.58124 1.000 29.91151  ? 317 GLU A H    1 
ATOM   4840 H  HA   . GLU A 1 337 ? -6.07963  -15.01837 -28.59453 1.000 30.08633  ? 317 GLU A HA   1 
ATOM   4841 H  HB2  . GLU A 1 337 ? -5.37390  -17.60778 -29.40730 1.000 33.40403  ? 317 GLU A HB2  1 
ATOM   4842 H  HB3  . GLU A 1 337 ? -6.15598  -17.32143 -28.05387 1.000 33.40403  ? 317 GLU A HB3  1 
ATOM   4843 H  HG2  . GLU A 1 337 ? -7.80125  -16.23935 -29.51696 1.000 39.92931  ? 317 GLU A HG2  1 
ATOM   4844 H  HG3  . GLU A 1 337 ? -7.12495  -17.11624 -30.65674 1.000 39.92931  ? 317 GLU A HG3  1 
ATOM   4845 N  N    . PRO A 1 338 ? -3.70796  -14.37197 -27.60534 1.000 22.18503  ? 318 PRO A N    1 
ATOM   4846 C  CA   . PRO A 1 338 ? -2.49006  -14.29127 -26.79479 1.000 22.51448  ? 318 PRO A CA   1 
ATOM   4847 C  C    . PRO A 1 338 ? -2.65793  -14.77258 -25.38136 1.000 21.95328  ? 318 PRO A C    1 
ATOM   4848 O  O    . PRO A 1 338 ? -1.64616  -15.08534 -24.74721 1.000 22.76302  ? 318 PRO A O    1 
ATOM   4849 C  CB   . PRO A 1 338 ? -2.13666  -12.79515 -26.84765 1.000 24.76105  ? 318 PRO A CB   1 
ATOM   4850 C  CG   . PRO A 1 338 ? -3.42452  -12.11661 -27.25270 1.000 27.03648  ? 318 PRO A CG   1 
ATOM   4851 C  CD   . PRO A 1 338 ? -4.16142  -13.06858 -28.10565 1.000 23.15401  ? 318 PRO A CD   1 
ATOM   4852 H  HA   . PRO A 1 338 ? -1.78162  -14.80454 -27.21380 1.000 27.04113  ? 318 PRO A HA   1 
ATOM   4853 H  HB2  . PRO A 1 338 ? -1.84228  -12.49228 -25.97443 1.000 29.73702  ? 318 PRO A HB2  1 
ATOM   4854 H  HB3  . PRO A 1 338 ? -1.43964  -12.64144 -27.50448 1.000 29.73702  ? 318 PRO A HB3  1 
ATOM   4855 H  HG2  . PRO A 1 338 ? -3.93981  -11.90219 -26.45935 1.000 32.46754  ? 318 PRO A HG2  1 
ATOM   4856 H  HG3  . PRO A 1 338 ? -3.22129  -11.30614 -27.74538 1.000 32.46754  ? 318 PRO A HG3  1 
ATOM   4857 H  HD2  . PRO A 1 338 ? -5.11934  -12.96717 -27.99163 1.000 27.80858  ? 318 PRO A HD2  1 
ATOM   4858 H  HD3  . PRO A 1 338 ? -3.92442  -12.95355 -29.03919 1.000 27.80858  ? 318 PRO A HD3  1 
ATOM   4859 N  N    . GLU A 1 339 ? -3.88125  -14.80746 -24.83460 1.000 22.03089  ? 319 GLU A N    1 
ATOM   4860 C  CA   . GLU A 1 339 ? -4.06279  -15.35359 -23.48185 1.000 24.74087  ? 319 GLU A CA   1 
ATOM   4861 C  C    . GLU A 1 339 ? -4.18305  -16.86007 -23.44956 1.000 26.92921  ? 319 GLU A C    1 
ATOM   4862 O  O    . GLU A 1 339 ? -4.45697  -17.44415 -22.38289 1.000 26.02335  ? 319 GLU A O    1 
ATOM   4863 C  CB   . GLU A 1 339 ? -5.29898  -14.70904 -22.82940 1.000 28.49749  ? 319 GLU A CB   1 
ATOM   4864 C  CG   . GLU A 1 339 ? -5.07813  -13.24888 -22.48268 1.000 29.12378  ? 319 GLU A CG   1 
ATOM   4865 C  CD   . GLU A 1 339 ? -4.25405  -13.02300 -21.22452 1.000 35.81526  ? 319 GLU A CD   1 
ATOM   4866 O  OE1  . GLU A 1 339 ? -3.87158  -14.00124 -20.52707 1.000 33.68570  ? 319 GLU A OE1  1 
ATOM   4867 O  OE2  . GLU A 1 339 ? -4.00286  -11.83047 -20.93336 1.000 33.12276  ? 319 GLU A OE2  1 
ATOM   4868 H  H    . GLU A 1 339 ? -4.59989  -14.52898 -25.21619 1.000 26.46083  ? 319 GLU A H    1 
ATOM   4869 H  HA   . GLU A 1 339 ? -3.28415  -15.12364 -22.95105 1.000 29.71280  ? 319 GLU A HA   1 
ATOM   4870 H  HB2  . GLU A 1 339 ? -6.04633  -14.76283 -23.44542 1.000 34.22074  ? 319 GLU A HB2  1 
ATOM   4871 H  HB3  . GLU A 1 339 ? -5.50906  -15.18480 -22.01060 1.000 34.22074  ? 319 GLU A HB3  1 
ATOM   4872 H  HG2  . GLU A 1 339 ? -4.61269  -12.82209 -23.21896 1.000 34.97230  ? 319 GLU A HG2  1 
ATOM   4873 H  HG3  . GLU A 1 339 ? -5.94157  -12.82803 -22.34749 1.000 34.97230  ? 319 GLU A HG3  1 
ATOM   4874 N  N    . LYS A 1 340 ? -3.98902  -17.51585 -24.58502 1.000 23.28214  ? 320 LYS A N    1 
ATOM   4875 C  CA   . LYS A 1 340 ? -3.85775  -18.96470 -24.62760 1.000 24.02397  ? 320 LYS A CA   1 
ATOM   4876 C  C    . LYS A 1 340 ? -2.36768  -19.31509 -24.55710 1.000 23.33812  ? 320 LYS A C    1 
ATOM   4877 O  O    . LYS A 1 340 ? -1.56292  -18.83828 -25.37989 1.000 26.01300  ? 320 LYS A O    1 
ATOM   4878 C  CB   . LYS A 1 340 ? -4.49767  -19.53322 -25.88315 1.000 24.04790  ? 320 LYS A CB   1 
ATOM   4879 C  CG   . LYS A 1 340 ? -4.64063  -21.04677 -25.90677 1.000 38.17101  ? 320 LYS A CG   1 
ATOM   4880 C  CD   . LYS A 1 340 ? -5.06827  -21.49168 -27.32056 1.000 48.89367  ? 320 LYS A CD   1 
ATOM   4881 C  CE   . LYS A 1 340 ? -5.05904  -22.99948 -27.49574 1.000 58.44838  ? 320 LYS A CE   1 
ATOM   4882 N  NZ   . LYS A 1 340 ? -3.91975  -23.43180 -28.34215 1.000 43.09993  ? 320 LYS A NZ   1 
ATOM   4883 H  H    . LYS A 1 340 ? -3.92895  -17.13850 -25.35547 1.000 27.96232  ? 320 LYS A H    1 
ATOM   4884 H  HA   . LYS A 1 340 ? -4.31004  -19.36207 -23.86705 1.000 28.85253  ? 320 LYS A HA   1 
ATOM   4885 H  HB2  . LYS A 1 340 ? -5.38708  -19.15630 -25.97136 1.000 28.88125  ? 320 LYS A HB2  1 
ATOM   4886 H  HB3  . LYS A 1 340 ? -3.95343  -19.28119 -26.64551 1.000 28.88125  ? 320 LYS A HB3  1 
ATOM   4887 H  HG2  . LYS A 1 340 ? -3.79151  -21.46223 -25.68934 1.000 45.82897  ? 320 LYS A HG2  1 
ATOM   4888 H  HG3  . LYS A 1 340 ? -5.31837  -21.32454 -25.27083 1.000 45.82897  ? 320 LYS A HG3  1 
ATOM   4889 H  HD2  . LYS A 1 340 ? -5.96971  -21.17681 -27.49135 1.000 58.69616  ? 320 LYS A HD2  1 
ATOM   4890 H  HD3  . LYS A 1 340 ? -4.45565  -21.11196 -27.96972 1.000 58.69616  ? 320 LYS A HD3  1 
ATOM   4891 H  HE2  . LYS A 1 340 ? -4.97510  -23.42463 -26.62793 1.000 70.16181  ? 320 LYS A HE2  1 
ATOM   4892 H  HE3  . LYS A 1 340 ? -5.88302  -23.27960 -27.92410 1.000 70.16181  ? 320 LYS A HE3  1 
ATOM   4893 H  HZ1  . LYS A 1 340 ? -3.92407  -24.31752 -28.42915 1.000 51.74367  ? 320 LYS A HZ1  1 
ATOM   4894 H  HZ2  . LYS A 1 340 ? -3.98261  -23.06198 -29.14923 1.000 51.74367  ? 320 LYS A HZ2  1 
ATOM   4895 H  HZ3  . LYS A 1 340 ? -3.15134  -23.18197 -27.96902 1.000 51.74367  ? 320 LYS A HZ3  1 
ATOM   4896 N  N    . PHE A 1 341 ? -1.98894  -20.12133 -23.57213 1.000 23.83253  ? 321 PHE A N    1 
ATOM   4897 C  CA   . PHE A 1 341 ? -0.62161  -20.63942 -23.52223 1.000 23.20914  ? 321 PHE A CA   1 
ATOM   4898 C  C    . PHE A 1 341 ? -0.51324  -21.85687 -24.43649 1.000 22.40568  ? 321 PHE A C    1 
ATOM   4899 O  O    . PHE A 1 341 ? -1.22848  -22.85416 -24.25097 1.000 24.89163  ? 321 PHE A O    1 
ATOM   4900 C  CB   . PHE A 1 341 ? -0.23227  -20.99874 -22.08310 1.000 23.21353  ? 321 PHE A CB   1 
ATOM   4901 C  CG   . PHE A 1 341 ? 1.20383   -21.38644 -21.89960 1.000 21.98229  ? 321 PHE A CG   1 
ATOM   4902 C  CD1  . PHE A 1 341 ? 2.16818   -20.44906 -21.59771 1.000 19.80068  ? 321 PHE A CD1  1 
ATOM   4903 C  CD2  . PHE A 1 341 ? 1.60147   -22.71953 -22.01649 1.000 24.71855  ? 321 PHE A CD2  1 
ATOM   4904 C  CE1  . PHE A 1 341 ? 3.50277   -20.82168 -21.44443 1.000 20.87125  ? 321 PHE A CE1  1 
ATOM   4905 C  CE2  . PHE A 1 341 ? 2.95891   -23.08763 -21.84878 1.000 23.90311  ? 321 PHE A CE2  1 
ATOM   4906 C  CZ   . PHE A 1 341 ? 3.89575   -22.12970 -21.54583 1.000 21.69883  ? 321 PHE A CZ   1 
ATOM   4907 H  H    . PHE A 1 341 ? -2.49623  -20.38121 -22.92814 1.000 28.62280  ? 321 PHE A H    1 
ATOM   4908 H  HA   . PHE A 1 341 ? -0.00490  -19.95952 -23.83576 1.000 27.87472  ? 321 PHE A HA   1 
ATOM   4909 H  HB2  . PHE A 1 341 ? -0.40142  -20.22941 -21.51705 1.000 27.88000  ? 321 PHE A HB2  1 
ATOM   4910 H  HB3  . PHE A 1 341 ? -0.77603  -21.74856 -21.79500 1.000 27.88000  ? 321 PHE A HB3  1 
ATOM   4911 H  HD1  . PHE A 1 341 ? 1.92560   -19.55714 -21.49503 1.000 23.78458  ? 321 PHE A HD1  1 
ATOM   4912 H  HD2  . PHE A 1 341 ? 0.96794   -23.37329 -22.20661 1.000 29.68603  ? 321 PHE A HD2  1 
ATOM   4913 H  HE1  . PHE A 1 341 ? 4.14030   -20.16758 -21.26944 1.000 25.06926  ? 321 PHE A HE1  1 
ATOM   4914 H  HE2  . PHE A 1 341 ? 3.21555   -23.97648 -21.94363 1.000 28.70750  ? 321 PHE A HE2  1 
ATOM   4915 H  HZ   . PHE A 1 341 ? 4.78505   -22.36626 -21.41137 1.000 26.06236  ? 321 PHE A HZ   1 
ATOM   4916 N  N    . ASP A 1 342 ? 0.33266   -21.76325 -25.46035 1.000 22.68761  ? 322 ASP A N    1 
ATOM   4917 C  CA   . ASP A 1 342 ? 0.44110   -22.80563 -26.48895 1.000 21.99278  ? 322 ASP A CA   1 
ATOM   4918 C  C    . ASP A 1 342 ? 1.90096   -23.07511 -26.83845 1.000 21.83720  ? 322 ASP A C    1 
ATOM   4919 O  O    . ASP A 1 342 ? 2.50041   -22.30710 -27.61095 1.000 21.78098  ? 322 ASP A O    1 
ATOM   4920 C  CB   . ASP A 1 342 ? -0.32445  -22.36200 -27.73478 1.000 24.28857  ? 322 ASP A CB   1 
ATOM   4921 C  CG   . ASP A 1 342 ? -0.43348  -23.43777 -28.78982 1.000 30.03755  ? 322 ASP A CG   1 
ATOM   4922 O  OD1  . ASP A 1 342 ? 0.27554   -24.46234 -28.75594 1.000 24.77883  ? 322 ASP A OD1  1 
ATOM   4923 O  OD2  . ASP A 1 342 ? -1.27799  -23.25413 -29.69060 1.000 29.49447  ? 322 ASP A OD2  1 
ATOM   4924 H  H    . ASP A 1 342 ? 0.86293   -21.09793 -25.58589 1.000 27.24889  ? 322 ASP A H    1 
ATOM   4925 H  HA   . ASP A 1 342 ? 0.08773   -23.63167 -26.12332 1.000 26.41510  ? 322 ASP A HA   1 
ATOM   4926 H  HB2  . ASP A 1 342 ? -1.22409  -22.10813 -27.47574 1.000 29.17004  ? 322 ASP A HB2  1 
ATOM   4927 H  HB3  . ASP A 1 342 ? 0.13334   -21.60377 -28.13028 1.000 29.17004  ? 322 ASP A HB3  1 
ATOM   4928 N  N    . VAL A 1 343 ? 2.42927   -24.20796 -26.34590 1.000 22.44119  ? 323 VAL A N    1 
ATOM   4929 C  CA   . VAL A 1 343 ? 3.84294   -24.51775 -26.55921 1.000 22.22569  ? 323 VAL A CA   1 
ATOM   4930 C  C    . VAL A 1 343 ? 4.17146   -24.70175 -28.03431 1.000 23.44960  ? 323 VAL A C    1 
ATOM   4931 O  O    . VAL A 1 343 ? 5.34445   -24.65016 -28.42630 1.000 24.77260  ? 323 VAL A O    1 
ATOM   4932 C  CB   . VAL A 1 343 ? 4.29262   -25.75691 -25.76210 1.000 23.05743  ? 323 VAL A CB   1 
ATOM   4933 C  CG1  . VAL A 1 343 ? 4.11925   -25.49551 -24.26143 1.000 23.75718  ? 323 VAL A CG1  1 
ATOM   4934 C  CG2  . VAL A 1 343 ? 3.58030   -27.01981 -26.19256 1.000 23.56670  ? 323 VAL A CG2  1 
ATOM   4935 H  H    . VAL A 1 343 ? 1.99564   -24.79807 -25.89498 1.000 26.95319  ? 323 VAL A H    1 
ATOM   4936 H  HA   . VAL A 1 343 ? 4.34083   -23.75710 -26.22097 1.000 26.69459  ? 323 VAL A HA   1 
ATOM   4937 H  HB   . VAL A 1 343 ? 5.23195   -25.91248 -25.94747 1.000 27.69268  ? 323 VAL A HB   1 
ATOM   4938 H  HG11 . VAL A 1 343 ? 4.45170   -26.26099 -23.76705 1.000 28.53238  ? 323 VAL A HG11 1 
ATOM   4939 H  HG12 . VAL A 1 343 ? 4.62136   -24.70176 -24.01906 1.000 28.53238  ? 323 VAL A HG12 1 
ATOM   4940 H  HG13 . VAL A 1 343 ? 3.17755   -25.36223 -24.07082 1.000 28.53238  ? 323 VAL A HG13 1 
ATOM   4941 H  HG21 . VAL A 1 343 ? 3.81092   -27.73655 -25.58100 1.000 28.30380  ? 323 VAL A HG21 1 
ATOM   4942 H  HG22 . VAL A 1 343 ? 2.62301   -26.86438 -26.17406 1.000 28.30380  ? 323 VAL A HG22 1 
ATOM   4943 H  HG23 . VAL A 1 343 ? 3.86078   -27.24956 -27.09225 1.000 28.30380  ? 323 VAL A HG23 1 
ATOM   4944 N  N    . GLN A 1 344 ? 3.15620   -24.92955 -28.88054 1.000 20.94996  ? 324 GLN A N    1 
ATOM   4945 C  CA   . GLN A 1 344 ? 3.36541   -25.17916 -30.29433 1.000 21.83258  ? 324 GLN A CA   1 
ATOM   4946 C  C    . GLN A 1 344 ? 3.30470   -23.90755 -31.13577 1.000 22.61775  ? 324 GLN A C    1 
ATOM   4947 O  O    . GLN A 1 344 ? 3.54003   -23.97253 -32.35727 1.000 23.57122  ? 324 GLN A O    1 
ATOM   4948 C  CB   . GLN A 1 344 ? 2.32863   -26.18112 -30.81225 1.000 23.37065  ? 324 GLN A CB   1 
ATOM   4949 C  CG   . GLN A 1 344 ? 2.35109   -27.51308 -30.11064 1.000 24.53614  ? 324 GLN A CG   1 
ATOM   4950 C  CD   . GLN A 1 344 ? 1.27430   -28.46212 -30.59463 1.000 24.25704  ? 324 GLN A CD   1 
ATOM   4951 O  OE1  . GLN A 1 344 ? 0.13452   -28.43397 -30.08888 1.000 27.20160  ? 324 GLN A OE1  1 
ATOM   4952 N  NE2  . GLN A 1 344 ? 1.61055   -29.30072 -31.54556 1.000 27.99434  ? 324 GLN A NE2  1 
ATOM   4953 H  H    . GLN A 1 344 ? 2.32887   -24.94264 -28.64614 1.000 25.16371  ? 324 GLN A H    1 
ATOM   4954 H  HA   . GLN A 1 344 ? 4.24463   -25.57221 -30.41004 1.000 26.22286  ? 324 GLN A HA   1 
ATOM   4955 H  HB2  . GLN A 1 344 ? 1.44413   -25.80109 -30.69331 1.000 28.06855  ? 324 GLN A HB2  1 
ATOM   4956 H  HB3  . GLN A 1 344 ? 2.49671   -26.34201 -31.75393 1.000 28.06855  ? 324 GLN A HB3  1 
ATOM   4957 H  HG2  . GLN A 1 344 ? 3.21094   -27.93482 -30.26457 1.000 29.46713  ? 324 GLN A HG2  1 
ATOM   4958 H  HG3  . GLN A 1 344 ? 2.21704   -27.37009 -29.16065 1.000 29.46713  ? 324 GLN A HG3  1 
ATOM   4959 H  HE21 . GLN A 1 344 ? 2.40984   -29.29301 -31.86285 1.000 33.61697  ? 324 GLN A HE21 1 
ATOM   4960 H  HE22 . GLN A 1 344 ? 1.03173   -29.85824 -31.85172 1.000 33.61697  ? 324 GLN A HE22 1 
ATOM   4961 N  N    . ARG A 1 345 ? 3.08426   -22.76966 -30.49908 1.000 24.10373  ? 325 ARG A N    1 
ATOM   4962 C  CA   . ARG A 1 345 ? 2.93830   -21.50624 -31.20632 1.000 22.14232  ? 325 ARG A CA   1 
ATOM   4963 C  C    . ARG A 1 345 ? 4.04295   -21.28562 -32.22614 1.000 25.82007  ? 325 ARG A C    1 
ATOM   4964 O  O    . ARG A 1 345 ? 5.24320   -21.31141 -31.90594 1.000 25.50641  ? 325 ARG A O    1 
ATOM   4965 C  CB   . ARG A 1 345 ? 2.91560   -20.38154 -30.15146 1.000 24.81666  ? 325 ARG A CB   1 
ATOM   4966 C  CG   . ARG A 1 345 ? 2.36266   -19.09429 -30.59926 1.000 26.04079  ? 325 ARG A CG   1 
ATOM   4967 C  CD   . ARG A 1 345 ? 2.21196   -18.09574 -29.44998 1.000 23.78841  ? 325 ARG A CD   1 
ATOM   4968 N  NE   . ARG A 1 345 ? 1.00598   -18.26445 -28.64358 1.000 20.33750  ? 325 ARG A NE   1 
ATOM   4969 C  CZ   . ARG A 1 345 ? -0.18143  -17.79333 -28.97940 1.000 22.34938  ? 325 ARG A CZ   1 
ATOM   4970 N  NH1  . ARG A 1 345 ? -0.37950  -17.22956 -30.15444 1.000 22.47118  ? 325 ARG A NH1  1 
ATOM   4971 N  NH2  . ARG A 1 345 ? -1.18938  -17.89456 -28.11404 1.000 22.52715  ? 325 ARG A NH2  1 
ATOM   4972 H  H    . ARG A 1 345 ? 3.01367   -22.69904 -29.64490 1.000 28.94823  ? 325 ARG A H    1 
ATOM   4973 H  HA   . ARG A 1 345 ? 2.10820   -21.50128 -31.70814 1.000 26.59455  ? 325 ARG A HA   1 
ATOM   4974 H  HB2  . ARG A 1 345 ? 2.37804   -20.67966 -29.40109 1.000 29.80375  ? 325 ARG A HB2  1 
ATOM   4975 H  HB3  . ARG A 1 345 ? 3.82692   -20.21777 -29.86239 1.000 29.80375  ? 325 ARG A HB3  1 
ATOM   4976 H  HG2  . ARG A 1 345 ? 2.95654   -18.70558 -31.26040 1.000 31.27271  ? 325 ARG A HG2  1 
ATOM   4977 H  HG3  . ARG A 1 345 ? 1.48592   -19.24218 -30.98701 1.000 31.27271  ? 325 ARG A HG3  1 
ATOM   4978 H  HD2  . ARG A 1 345 ? 2.97375   -18.19108 -28.85711 1.000 28.56986  ? 325 ARG A HD2  1 
ATOM   4979 H  HD3  . ARG A 1 345 ? 2.19049   -17.19980 -29.82110 1.000 28.56986  ? 325 ARG A HD3  1 
ATOM   4980 H  HE   . ARG A 1 345 ? 1.07319   -18.69768 -27.90372 1.000 24.42876  ? 325 ARG A HE   1 
ATOM   4981 H  HH11 . ARG A 1 345 ? 0.26945   -17.16442 -30.71498 1.000 26.98918  ? 325 ARG A HH11 1 
ATOM   4982 H  HH12 . ARG A 1 345 ? -1.15768  -16.92691 -30.36046 1.000 26.98918  ? 325 ARG A HH12 1 
ATOM   4983 H  HH21 . ARG A 1 345 ? -1.06259  -18.26318 -27.34745 1.000 27.05634  ? 325 ARG A HH21 1 
ATOM   4984 H  HH22 . ARG A 1 345 ? -1.96679  -17.59129 -28.32203 1.000 27.05634  ? 325 ARG A HH22 1 
ATOM   4985 N  N    . ASN A 1 346 ? 3.62978   -21.06251 -33.44901 1.000 25.48439  ? 326 ASN A N    1 
ATOM   4986 C  CA   . ASN A 1 346 ? 4.54445   -20.80619 -34.53459 1.000 29.06839  ? 326 ASN A CA   1 
ATOM   4987 C  C    . ASN A 1 346 ? 3.82150   -19.89627 -35.52450 1.000 34.50476  ? 326 ASN A C    1 
ATOM   4988 O  O    . ASN A 1 346 ? 2.74793   -20.25878 -36.04610 1.000 32.23137  ? 326 ASN A O    1 
ATOM   4989 C  CB   . ASN A 1 346 ? 4.97152   -22.11643 -35.18443 1.000 36.65493  ? 326 ASN A CB   1 
ATOM   4990 C  CG   . ASN A 1 346 ? 5.76455   -21.89228 -36.43089 1.000 47.82498  ? 326 ASN A CG   1 
ATOM   4991 O  OD1  . ASN A 1 346 ? 6.26381   -20.79454 -36.66018 1.000 48.54712  ? 326 ASN A OD1  1 
ATOM   4992 N  ND2  . ASN A 1 346 ? 5.88326   -22.92365 -37.25685 1.000 51.34295  ? 326 ASN A ND2  1 
ATOM   4993 H  H    . ASN A 1 346 ? 2.80264   -21.05356 -33.68431 1.000 30.60503  ? 326 ASN A H    1 
ATOM   4994 H  HA   . ASN A 1 346 ? 5.35470   -20.36914 -34.22898 1.000 34.90583  ? 326 ASN A HA   1 
ATOM   4995 H  HB2  . ASN A 1 346 ? 5.52140   -22.61687 -34.56146 1.000 44.00968  ? 326 ASN A HB2  1 
ATOM   4996 H  HB3  . ASN A 1 346 ? 4.18169   -22.62965 -35.41613 1.000 44.00968  ? 326 ASN A HB3  1 
ATOM   4997 H  HD21 . ASN A 1 346 ? 5.51266   -23.67499 -37.06258 1.000 61.63531  ? 326 ASN A HD21 1 
ATOM   4998 H  HD22 . ASN A 1 346 ? 6.33081   -22.84088 -37.98654 1.000 61.63531  ? 326 ASN A HD22 1 
ATOM   4999 N  N    . PRO A 1 347 ? 4.37104   -18.71558 -35.83076 1.000 32.96565  ? 327 PRO A N    1 
ATOM   5000 C  CA   . PRO A 1 347 ? 5.61667   -18.14834 -35.28486 1.000 32.56398  ? 327 PRO A CA   1 
ATOM   5001 C  C    . PRO A 1 347 ? 5.43710   -17.68768 -33.84885 1.000 25.75280  ? 327 PRO A C    1 
ATOM   5002 O  O    . PRO A 1 347 ? 4.32607   -17.53493 -33.32970 1.000 26.89640  ? 327 PRO A O    1 
ATOM   5003 C  CB   . PRO A 1 347 ? 5.90685   -16.96880 -36.23786 1.000 35.20969  ? 327 PRO A CB   1 
ATOM   5004 C  CG   . PRO A 1 347 ? 4.56255   -16.48925 -36.62964 1.000 36.38484  ? 327 PRO A CG   1 
ATOM   5005 C  CD   . PRO A 1 347 ? 3.69974   -17.77497 -36.75489 1.000 36.55003  ? 327 PRO A CD   1 
ATOM   5006 H  HA   . PRO A 1 347 ? 6.35628   -18.77420 -35.33155 1.000 39.10053  ? 327 PRO A HA   1 
ATOM   5007 H  HB2  . PRO A 1 347 ? 6.40451   -16.27789 -35.77323 1.000 42.27539  ? 327 PRO A HB2  1 
ATOM   5008 H  HB3  . PRO A 1 347 ? 6.40816   -17.27714 -37.00891 1.000 42.27539  ? 327 PRO A HB3  1 
ATOM   5009 H  HG2  . PRO A 1 347 ? 4.20913   -15.89959 -35.94531 1.000 43.68557  ? 327 PRO A HG2  1 
ATOM   5010 H  HG3  . PRO A 1 347 ? 4.61242   -16.02095 -37.47765 1.000 43.68557  ? 327 PRO A HG3  1 
ATOM   5011 H  HD2  . PRO A 1 347 ? 2.78594   -17.60771 -36.47582 1.000 43.88380  ? 327 PRO A HD2  1 
ATOM   5012 H  HD3  . PRO A 1 347 ? 3.71235   -18.11366 -37.66375 1.000 43.88380  ? 327 PRO A HD3  1 
ATOM   5013 N  N    . ASN A 1 348 ? 6.56048   -17.42404 -33.17569 1.000 22.92955  ? 328 ASN A N    1 
ATOM   5014 C  CA   . ASN A 1 348 ? 6.50868   -16.91523 -31.82041 1.000 21.19672  ? 328 ASN A CA   1 
ATOM   5015 C  C    . ASN A 1 348 ? 7.63239   -15.89238 -31.65808 1.000 23.84235  ? 328 ASN A C    1 
ATOM   5016 O  O    . ASN A 1 348 ? 8.56744   -16.07273 -30.86254 1.000 22.90982  ? 328 ASN A O    1 
ATOM   5017 C  CB   . ASN A 1 348 ? 6.62051   -18.03758 -30.77582 1.000 20.62014  ? 328 ASN A CB   1 
ATOM   5018 C  CG   . ASN A 1 348 ? 6.16715   -17.56515 -29.40260 1.000 22.64623  ? 328 ASN A CG   1 
ATOM   5019 O  OD1  . ASN A 1 348 ? 5.98775   -16.34261 -29.17547 1.000 24.51334  ? 328 ASN A OD1  1 
ATOM   5020 N  ND2  . ASN A 1 348 ? 5.98539   -18.50719 -28.46945 1.000 21.77974  ? 328 ASN A ND2  1 
ATOM   5021 H  H    . ASN A 1 348 ? 7.35392   -17.53411 -33.48866 1.000 27.53922  ? 328 ASN A H    1 
ATOM   5022 H  HA   . ASN A 1 348 ? 5.65743   -16.47004 -31.68600 1.000 25.45982  ? 328 ASN A HA   1 
ATOM   5023 H  HB2  . ASN A 1 348 ? 6.05973   -18.78248 -31.04331 1.000 24.76793  ? 328 ASN A HB2  1 
ATOM   5024 H  HB3  . ASN A 1 348 ? 7.54471   -18.32478 -30.71052 1.000 24.76793  ? 328 ASN A HB3  1 
ATOM   5025 H  HD21 . ASN A 1 348 ? 5.72943   -18.28560 -27.67889 1.000 26.15945  ? 328 ASN A HD21 1 
ATOM   5026 H  HD22 . ASN A 1 348 ? 6.12456   -19.33409 -28.66039 1.000 26.15945  ? 328 ASN A HD22 1 
ATOM   5027 N  N    . SER A 1 349 ? 7.51999   -14.78217 -32.38625 1.000 22.12903  ? 329 SER A N    1 
ATOM   5028 C  CA   . SER A 1 349 ? 8.56175   -13.75382 -32.38763 1.000 22.14322  ? 329 SER A CA   1 
ATOM   5029 C  C    . SER A 1 349 ? 8.38085   -12.75197 -31.24911 1.000 21.61186  ? 329 SER A C    1 
ATOM   5030 O  O    . SER A 1 349 ? 8.21421   -11.54759 -31.44958 1.000 21.65339  ? 329 SER A O    1 
ATOM   5031 C  CB   . SER A 1 349 ? 8.56128   -13.04667 -33.73145 1.000 27.38216  ? 329 SER A CB   1 
ATOM   5032 O  OG   . SER A 1 349 ? 8.79987   -13.97018 -34.79225 1.000 31.92760  ? 329 SER A OG   1 
ATOM   5033 H  H    . SER A 1 349 ? 6.84733   -14.59983 -32.89012 1.000 26.57860  ? 329 SER A H    1 
ATOM   5034 H  HA   . SER A 1 349 ? 9.41604   -14.19114 -32.24674 1.000 26.59562  ? 329 SER A HA   1 
ATOM   5035 H  HB2  . SER A 1 349 ? 7.69737   -12.62687 -33.86683 1.000 32.88235  ? 329 SER A HB2  1 
ATOM   5036 H  HB3  . SER A 1 349 ? 9.26082   -12.37472 -33.73470 1.000 32.88235  ? 329 SER A HB3  1 
ATOM   5037 H  HG   . SER A 1 349 ? 8.67957   -13.59367 -35.53344 1.000 38.33689  ? 329 SER A HG   1 
ATOM   5038 N  N    . HIS A 1 350 ? 8.43476   -13.27026 -30.02134 1.000 19.41392  ? 330 HIS A N    1 
ATOM   5039 C  CA   . HIS A 1 350 ? 8.20731   -12.45510 -28.84328 1.000 17.62445  ? 330 HIS A CA   1 
ATOM   5040 C  C    . HIS A 1 350 ? 9.39252   -11.51334 -28.57611 1.000 19.02355  ? 330 HIS A C    1 
ATOM   5041 O  O    . HIS A 1 350 ? 10.49051  -11.65193 -29.14716 1.000 19.15553  ? 330 HIS A O    1 
ATOM   5042 C  CB   . HIS A 1 350 ? 7.97279   -13.31488 -27.59863 1.000 19.36868  ? 330 HIS A CB   1 
ATOM   5043 C  CG   . HIS A 1 350 ? 9.14773   -14.12731 -27.23968 1.000 19.33033  ? 330 HIS A CG   1 
ATOM   5044 N  ND1  . HIS A 1 350 ? 10.23183  -13.57362 -26.59331 1.000 17.91704  ? 330 HIS A ND1  1 
ATOM   5045 C  CD2  . HIS A 1 350 ? 9.47984   -15.40027 -27.54658 1.000 21.20493  ? 330 HIS A CD2  1 
ATOM   5046 C  CE1  . HIS A 1 350 ? 11.18438  -14.49786 -26.50259 1.000 20.27714  ? 330 HIS A CE1  1 
ATOM   5047 N  NE2  . HIS A 1 350 ? 10.74170  -15.61894 -27.05268 1.000 20.38998  ? 330 HIS A NE2  1 
ATOM   5048 H  H    . HIS A 1 350 ? 8.60248   -14.09592 -29.84882 1.000 23.32047  ? 330 HIS A H    1 
ATOM   5049 H  HA   . HIS A 1 350 ? 7.41236   -11.92291 -29.00369 1.000 21.17311  ? 330 HIS A HA   1 
ATOM   5050 H  HB2  . HIS A 1 350 ? 7.76748   -12.73537 -26.84835 1.000 23.26617  ? 330 HIS A HB2  1 
ATOM   5051 H  HB3  . HIS A 1 350 ? 7.23076   -13.91686 -27.76564 1.000 23.26617  ? 330 HIS A HB3  1 
ATOM   5052 H  HD2  . HIS A 1 350 ? 8.95260   -16.01325 -28.00613 1.000 25.46968  ? 330 HIS A HD2  1 
ATOM   5053 H  HE1  . HIS A 1 350 ? 12.02203  -14.37709 -26.11702 1.000 24.35633  ? 330 HIS A HE1  1 
ATOM   5054 H  HE2  . HIS A 1 350 ? 11.17381  -16.36137 -27.09357 1.000 24.49173  ? 330 HIS A HE2  1 
ATOM   5055 N  N    . LEU A 1 351 ? 9.11439   -10.51100 -27.74750 1.000 18.75535  ? 331 LEU A N    1 
ATOM   5056 C  CA   . LEU A 1 351 ? 10.06225  -9.46113  -27.38699 1.000 19.62023  ? 331 LEU A CA   1 
ATOM   5057 C  C    . LEU A 1 351 ? 10.54556  -9.55820  -25.94882 1.000 18.39713  ? 331 LEU A C    1 
ATOM   5058 O  O    . LEU A 1 351 ? 10.97929  -8.55087  -25.37869 1.000 18.88146  ? 331 LEU A O    1 
ATOM   5059 C  CB   . LEU A 1 351 ? 9.43189   -8.08428  -27.61946 1.000 18.24898  ? 331 LEU A CB   1 
ATOM   5060 C  CG   . LEU A 1 351 ? 8.95071   -7.85049  -29.01933 1.000 19.90836  ? 331 LEU A CG   1 
ATOM   5061 C  CD1  . LEU A 1 351 ? 8.48170   -6.39439  -29.28805 1.000 21.17994  ? 331 LEU A CD1  1 
ATOM   5062 C  CD2  . LEU A 1 351 ? 9.96165   -8.23980  -30.06716 1.000 24.76417  ? 331 LEU A CD2  1 
ATOM   5063 H  H    . LEU A 1 351 ? 8.35026   -10.41356 -27.36512 1.000 22.53019  ? 331 LEU A H    1 
ATOM   5064 H  HA   . LEU A 1 351 ? 10.83965  -9.56203  -27.95827 1.000 23.56804  ? 331 LEU A HA   1 
ATOM   5065 H  HB2  . LEU A 1 351 ? 8.66951   -7.99013  -27.02717 1.000 21.92253  ? 331 LEU A HB2  1 
ATOM   5066 H  HB3  . LEU A 1 351 ? 10.09381  -7.40419  -27.41889 1.000 21.92253  ? 331 LEU A HB3  1 
ATOM   5067 H  HG   . LEU A 1 351 ? 8.17854   -8.43154  -29.10331 1.000 23.91380  ? 331 LEU A HG   1 
ATOM   5068 H  HD11 . LEU A 1 351 ? 8.12644   -6.33820  -30.18890 1.000 25.43969  ? 331 LEU A HD11 1 
ATOM   5069 H  HD12 . LEU A 1 351 ? 7.79331   -6.16074  -28.64584 1.000 25.43969  ? 331 LEU A HD12 1 
ATOM   5070 H  HD13 . LEU A 1 351 ? 9.23926   -5.79603  -29.19331 1.000 25.43969  ? 331 LEU A HD13 1 
ATOM   5071 H  HD21 . LEU A 1 351 ? 9.67052   -7.90097  -30.92817 1.000 29.74076  ? 331 LEU A HD21 1 
ATOM   5072 H  HD22 . LEU A 1 351 ? 10.82158  -7.85614  -29.83429 1.000 29.74076  ? 331 LEU A HD22 1 
ATOM   5073 H  HD23 . LEU A 1 351 ? 10.02834  -9.20703  -30.09770 1.000 29.74076  ? 331 LEU A HD23 1 
ATOM   5074 N  N    . ALA A 1 352 ? 10.56894  -10.75824 -25.34806 1.000 17.22036  ? 332 ALA A N    1 
ATOM   5075 C  CA   . ALA A 1 352 ? 11.05610  -10.87482 -23.98399 1.000 17.49991  ? 332 ALA A CA   1 
ATOM   5076 C  C    . ALA A 1 352 ? 12.50114  -10.44554 -23.84833 1.000 16.44189  ? 332 ALA A C    1 
ATOM   5077 O  O    . ALA A 1 352 ? 12.89341  -9.95595  -22.77914 1.000 18.12136  ? 332 ALA A O    1 
ATOM   5078 C  CB   . ALA A 1 352 ? 10.94948  -12.30464 -23.46517 1.000 17.79706  ? 332 ALA A CB   1 
ATOM   5079 H  H    . ALA A 1 352 ? 10.31290  -11.49687 -25.70649 1.000 20.68819  ? 332 ALA A H    1 
ATOM   5080 H  HA   . ALA A 1 352 ? 10.48901  -10.29994 -23.44657 1.000 21.02366  ? 332 ALA A HA   1 
ATOM   5081 H  HB1  . ALA A 1 352 ? 11.31406  -12.34273 -22.56710 1.000 21.38023  ? 332 ALA A HB1  1 
ATOM   5082 H  HB2  . ALA A 1 352 ? 10.01598  -12.56799 -23.45465 1.000 21.38023  ? 332 ALA A HB2  1 
ATOM   5083 H  HB3  . ALA A 1 352 ? 11.45218  -12.89161 -24.05140 1.000 21.38023  ? 332 ALA A HB3  1 
ATOM   5084 N  N    . PHE A 1 353 ? 13.29413  -10.64625 -24.90578 1.000 16.87013  ? 333 PHE A N    1 
ATOM   5085 C  CA   . PHE A 1 353 ? 14.71071  -10.25428 -24.94448 1.000 18.59227  ? 333 PHE A CA   1 
ATOM   5086 C  C    . PHE A 1 353 ? 14.91886  -8.92665  -25.66827 1.000 19.64486  ? 333 PHE A C    1 
ATOM   5087 O  O    . PHE A 1 353 ? 16.05778  -8.56716  -26.00905 1.000 19.47182  ? 333 PHE A O    1 
ATOM   5088 C  CB   . PHE A 1 353 ? 15.54937  -11.31649 -25.63130 1.000 18.44361  ? 333 PHE A CB   1 
ATOM   5089 C  CG   . PHE A 1 353 ? 15.63312  -12.61978 -24.90686 1.000 18.58019  ? 333 PHE A CG   1 
ATOM   5090 C  CD1  . PHE A 1 353 ? 16.22134  -12.69370 -23.63709 1.000 18.53675  ? 333 PHE A CD1  1 
ATOM   5091 C  CD2  . PHE A 1 353 ? 15.20287  -13.80093 -25.51499 1.000 19.41612  ? 333 PHE A CD2  1 
ATOM   5092 C  CE1  . PHE A 1 353 ? 16.36408  -13.90937 -22.96445 1.000 20.46570  ? 333 PHE A CE1  1 
ATOM   5093 C  CE2  . PHE A 1 353 ? 15.31648  -15.03279 -24.84651 1.000 19.96857  ? 333 PHE A CE2  1 
ATOM   5094 C  CZ   . PHE A 1 353 ? 15.89786  -15.08953 -23.57612 1.000 17.68667  ? 333 PHE A CZ   1 
ATOM   5095 H  H    . PHE A 1 353 ? 13.02845  -11.01818 -25.63426 1.000 20.26791  ? 333 PHE A H    1 
ATOM   5096 H  HA   . PHE A 1 353 ? 15.01993  -10.17249 -24.02873 1.000 22.33449  ? 333 PHE A HA   1 
ATOM   5097 H  HB2  . PHE A 1 353 ? 15.16604  -11.49330 -26.50463 1.000 22.15610  ? 333 PHE A HB2  1 
ATOM   5098 H  HB3  . PHE A 1 353 ? 16.45356  -10.97889 -25.72804 1.000 22.15610  ? 333 PHE A HB3  1 
ATOM   5099 H  HD1  . PHE A 1 353 ? 16.52440  -11.91336 -23.23197 1.000 22.26786  ? 333 PHE A HD1  1 
ATOM   5100 H  HD2  . PHE A 1 353 ? 14.83786  -13.77256 -26.36989 1.000 23.32311  ? 333 PHE A HD2  1 
ATOM   5101 H  HE1  . PHE A 1 353 ? 16.76152  -13.93929 -22.12418 1.000 24.58261  ? 333 PHE A HE1  1 
ATOM   5102 H  HE2  . PHE A 1 353 ? 15.00460  -15.81062 -25.24978 1.000 23.98605  ? 333 PHE A HE2  1 
ATOM   5103 H  HZ   . PHE A 1 353 ? 15.97660  -15.90491 -23.13582 1.000 21.24777  ? 333 PHE A HZ   1 
ATOM   5104 N  N    . GLY A 1 354 ? 13.82788  -8.21661  -25.97554 1.000 17.85347  ? 334 GLY A N    1 
ATOM   5105 C  CA   . GLY A 1 354 ? 13.91377  -7.01897  -26.77168 1.000 18.73577  ? 334 GLY A CA   1 
ATOM   5106 C  C    . GLY A 1 354 ? 14.19962  -7.30762  -28.23968 1.000 20.16438  ? 334 GLY A C    1 
ATOM   5107 O  O    . GLY A 1 354 ? 13.88337  -8.36779  -28.78113 1.000 20.56053  ? 334 GLY A O    1 
ATOM   5108 H  H    . GLY A 1 354 ? 13.02890  -8.41751  -25.72881 1.000 21.44793  ? 334 GLY A H    1 
ATOM   5109 H  HA2  . GLY A 1 354 ? 13.07451  -6.53599  -26.71454 1.000 22.50669  ? 334 GLY A HA2  1 
ATOM   5110 H  HA3  . GLY A 1 354 ? 14.62567  -6.45680  -26.42807 1.000 22.50669  ? 334 GLY A HA3  1 
ATOM   5111 N  N    . PHE A 1 355 ? 14.84753  -6.34460  -28.88540 1.000 20.75569  ? 335 PHE A N    1 
ATOM   5112 C  CA   . PHE A 1 355 ? 15.04556  -6.33722  -30.33216 1.000 22.58488  ? 335 PHE A CA   1 
ATOM   5113 C  C    . PHE A 1 355 ? 16.03724  -5.24704  -30.69720 1.000 24.53314  ? 335 PHE A C    1 
ATOM   5114 O  O    . PHE A 1 355 ? 16.00089  -4.14742  -30.13014 1.000 25.38454  ? 335 PHE A O    1 
ATOM   5115 C  CB   . PHE A 1 355 ? 13.72841  -6.07971  -31.07481 1.000 22.71084  ? 335 PHE A CB   1 
ATOM   5116 C  CG   . PHE A 1 355 ? 13.87468  -6.06194  -32.54776 1.000 25.65677  ? 335 PHE A CG   1 
ATOM   5117 C  CD1  . PHE A 1 355 ? 13.89669  -7.26201  -33.24103 1.000 32.35928  ? 335 PHE A CD1  1 
ATOM   5118 C  CD2  . PHE A 1 355 ? 13.98764  -4.88140  -33.26556 1.000 27.56814  ? 335 PHE A CD2  1 
ATOM   5119 C  CE1  . PHE A 1 355 ? 14.02954  -7.28363  -34.61516 1.000 37.07834  ? 335 PHE A CE1  1 
ATOM   5120 C  CE2  . PHE A 1 355 ? 14.12622  -4.90527  -34.65657 1.000 32.20767  ? 335 PHE A CE2  1 
ATOM   5121 C  CZ   . PHE A 1 355 ? 14.14639  -6.10239  -35.31245 1.000 34.32511  ? 335 PHE A CZ   1 
ATOM   5122 H  H    . PHE A 1 355 ? 15.19421  -5.66056  -28.49618 1.000 24.93058  ? 335 PHE A H    1 
ATOM   5123 H  HA   . PHE A 1 355 ? 15.40451  -7.19704  -30.60190 1.000 27.12562  ? 335 PHE A HA   1 
ATOM   5124 H  HB2  . PHE A 1 355 ? 13.09860  -6.78147  -30.84723 1.000 27.27677  ? 335 PHE A HB2  1 
ATOM   5125 H  HB3  . PHE A 1 355 ? 13.37802  -5.21777  -30.80062 1.000 27.27677  ? 335 PHE A HB3  1 
ATOM   5126 H  HD1  . PHE A 1 355 ? 13.82099  -8.06300  -32.77457 1.000 38.85490  ? 335 PHE A HD1  1 
ATOM   5127 H  HD2  . PHE A 1 355 ? 13.97110  -4.06639  -32.81792 1.000 33.10552  ? 335 PHE A HD2  1 
ATOM   5128 H  HE1  . PHE A 1 355 ? 14.04007  -8.09522  -35.06914 1.000 44.51776  ? 335 PHE A HE1  1 
ATOM   5129 H  HE2  . PHE A 1 355 ? 14.20423  -4.11004  -35.13240 1.000 38.67297  ? 335 PHE A HE2  1 
ATOM   5130 H  HZ   . PHE A 1 355 ? 14.23981  -6.12007  -36.23758 1.000 41.21389  ? 335 PHE A HZ   1 
ATOM   5131 N  N    . GLY A 1 356 ? 16.87784  -5.53919  -31.68016 1.000 23.79669  ? 336 GLY A N    1 
ATOM   5132 C  CA   . GLY A 1 356 ? 17.77085  -4.52349  -32.21040 1.000 26.66341  ? 336 GLY A CA   1 
ATOM   5133 C  C    . GLY A 1 356 ? 19.13567  -4.45004  -31.56396 1.000 23.70405  ? 336 GLY A C    1 
ATOM   5134 O  O    . GLY A 1 356 ? 19.66258  -5.45832  -31.10833 1.000 24.18210  ? 336 GLY A O    1 
ATOM   5135 H  H    . GLY A 1 356 ? 16.94885  -6.31100  -32.05280 1.000 28.57979  ? 336 GLY A H    1 
ATOM   5136 H  HA2  . GLY A 1 356 ? 17.90459  -4.69407  -33.15587 1.000 32.01985  ? 336 GLY A HA2  1 
ATOM   5137 H  HA3  . GLY A 1 356 ? 17.34978  -3.65634  -32.10242 1.000 32.01985  ? 336 GLY A HA3  1 
ATOM   5138 N  N    . THR A 1 357 ? 19.66762  -3.22657  -31.51264 1.000 23.03721  ? 337 THR A N    1 
ATOM   5139 C  CA   . THR A 1 357 ? 20.99887  -2.92193  -31.00844 1.000 28.21013  ? 337 THR A CA   1 
ATOM   5140 C  C    . THR A 1 357 ? 21.28054  -3.58556  -29.66237 1.000 24.77536  ? 337 THR A C    1 
ATOM   5141 O  O    . THR A 1 357 ? 22.38233  -4.10535  -29.43791 1.000 25.53827  ? 337 THR A O    1 
ATOM   5142 C  CB   . THR A 1 357 ? 21.08766  -1.37589  -30.86662 1.000 28.72350  ? 337 THR A CB   1 
ATOM   5143 O  OG1  . THR A 1 357 ? 20.85699  -0.75021  -32.13667 1.000 36.47595  ? 337 THR A OG1  1 
ATOM   5144 C  CG2  . THR A 1 357 ? 22.33915  -0.92954  -30.32164 1.000 31.85774  ? 337 THR A CG2  1 
ATOM   5145 H  H    . THR A 1 357 ? 19.25422  -2.52079  -31.77829 1.000 27.66842  ? 337 THR A H    1 
ATOM   5146 H  HA   . THR A 1 357 ? 21.66926  -3.25308  -31.62635 1.000 33.87591  ? 337 THR A HA   1 
ATOM   5147 H  HB   . THR A 1 357 ? 20.40300  -1.10027  -30.23720 1.000 34.49196  ? 337 THR A HB   1 
ATOM   5148 H  HG1  . THR A 1 357 ? 20.06018  -0.86858  -32.37475 1.000 43.79491  ? 337 THR A HG1  1 
ATOM   5149 H  HG21 . THR A 1 357 ? 22.43968  0.02523   -30.46024 1.000 38.25305  ? 337 THR A HG21 1 
ATOM   5150 H  HG22 . THR A 1 357 ? 22.37146  -1.11463  -29.37001 1.000 38.25305  ? 337 THR A HG22 1 
ATOM   5151 H  HG23 . THR A 1 357 ? 23.07362  -1.38989  -30.75699 1.000 38.25305  ? 337 THR A HG23 1 
ATOM   5152 N  N    . HIS A 1 358 ? 20.30919  -3.56661  -28.76179 1.000 21.79473  ? 338 HIS A N    1 
ATOM   5153 C  CA   . HIS A 1 358 ? 20.51151  -4.00091  -27.38532 1.000 21.23555  ? 338 HIS A CA   1 
ATOM   5154 C  C    . HIS A 1 358 ? 19.92807  -5.36799  -27.09349 1.000 23.02267  ? 338 HIS A C    1 
ATOM   5155 O  O    . HIS A 1 358 ? 19.86717  -5.74246  -25.92718 1.000 21.18421  ? 338 HIS A O    1 
ATOM   5156 C  CB   . HIS A 1 358 ? 19.92569  -2.95396  -26.42372 1.000 22.19687  ? 338 HIS A CB   1 
ATOM   5157 C  CG   . HIS A 1 358 ? 20.65352  -1.63831  -26.46031 1.000 21.47693  ? 338 HIS A CG   1 
ATOM   5158 N  ND1  . HIS A 1 358 ? 21.80985  -1.40840  -25.74146 1.000 22.50136  ? 338 HIS A ND1  1 
ATOM   5159 C  CD2  . HIS A 1 358 ? 20.40651  -0.50170  -27.15411 1.000 22.20105  ? 338 HIS A CD2  1 
ATOM   5160 C  CE1  . HIS A 1 358 ? 22.24656  -0.18620  -26.00436 1.000 23.80137  ? 338 HIS A CE1  1 
ATOM   5161 N  NE2  . HIS A 1 358 ? 21.41410  0.38762   -26.85825 1.000 22.73441  ? 338 HIS A NE2  1 
ATOM   5162 H  H    . HIS A 1 358 ? 19.50774  -3.30137  -28.92588 1.000 26.17744  ? 338 HIS A H    1 
ATOM   5163 H  HA   . HIS A 1 358 ? 21.46552  -4.06464  -27.22195 1.000 25.50643  ? 338 HIS A HA   1 
ATOM   5164 H  HB2  . HIS A 1 358 ? 19.00070  -2.78946  -26.66503 1.000 26.66000  ? 338 HIS A HB2  1 
ATOM   5165 H  HB3  . HIS A 1 358 ? 19.97624  -3.29723  -25.51790 1.000 26.66000  ? 338 HIS A HB3  1 
ATOM   5166 H  HD1  . HIS A 1 358 ? 22.18600  -1.96891  -25.20861 1.000 27.02539  ? 338 HIS A HD1  1 
ATOM   5167 H  HD2  . HIS A 1 358 ? 19.68833  -0.35017  -27.72521 1.000 26.66502  ? 338 HIS A HD2  1 
ATOM   5168 H  HE1  . HIS A 1 358 ? 23.01166  0.20428   -25.64792 1.000 28.58541  ? 338 HIS A HE1  1 
ATOM   5169 N  N    . PHE A 1 359 ? 19.49905  -6.11234  -28.11291 1.000 21.94729  ? 339 PHE A N    1 
ATOM   5170 C  CA   . PHE A 1 359 ? 18.95768  -7.46288  -27.94567 1.000 21.25728  ? 339 PHE A CA   1 
ATOM   5171 C  C    . PHE A 1 359 ? 19.80239  -8.27350  -26.95574 1.000 21.26462  ? 339 PHE A C    1 
ATOM   5172 O  O    . PHE A 1 359 ? 21.02873  -8.37849  -27.11198 1.000 21.58719  ? 339 PHE A O    1 
ATOM   5173 C  CB   . PHE A 1 359 ? 18.92638  -8.14103  -29.33751 1.000 21.30282  ? 339 PHE A CB   1 
ATOM   5174 C  CG   . PHE A 1 359 ? 18.46453  -9.56880  -29.29287 1.000 25.40005  ? 339 PHE A CG   1 
ATOM   5175 C  CD1  . PHE A 1 359 ? 17.14986  -9.84713  -29.02916 1.000 23.44164  ? 339 PHE A CD1  1 
ATOM   5176 C  CD2  . PHE A 1 359 ? 19.33839  -10.61693 -29.54597 1.000 30.33518  ? 339 PHE A CD2  1 
ATOM   5177 C  CE1  . PHE A 1 359 ? 16.68036  -11.14603 -28.94960 1.000 28.19949  ? 339 PHE A CE1  1 
ATOM   5178 C  CE2  . PHE A 1 359 ? 18.87977  -11.92697 -29.47856 1.000 32.15570  ? 339 PHE A CE2  1 
ATOM   5179 C  CZ   . PHE A 1 359 ? 17.56363  -12.18599 -29.16788 1.000 27.97383  ? 339 PHE A CZ   1 
ATOM   5180 H  H    . PHE A 1 359 ? 19.51072  -5.85235  -28.93259 1.000 26.36051  ? 339 PHE A H    1 
ATOM   5181 H  HA   . PHE A 1 359 ? 18.05576  -7.43107  -27.59010 1.000 25.53249  ? 339 PHE A HA   1 
ATOM   5182 H  HB2  . PHE A 1 359 ? 18.31910  -7.64935  -29.91228 1.000 25.58714  ? 339 PHE A HB2  1 
ATOM   5183 H  HB3  . PHE A 1 359 ? 19.82093  -8.12890  -29.71240 1.000 25.58714  ? 339 PHE A HB3  1 
ATOM   5184 H  HD1  . PHE A 1 359 ? 16.55599  -9.14320  -28.89994 1.000 28.15373  ? 339 PHE A HD1  1 
ATOM   5185 H  HD2  . PHE A 1 359 ? 20.22670  -10.44333 -29.75967 1.000 36.42598  ? 339 PHE A HD2  1 
ATOM   5186 H  HE1  . PHE A 1 359 ? 15.78741  -11.31600 -28.75298 1.000 33.86316  ? 339 PHE A HE1  1 
ATOM   5187 H  HE2  . PHE A 1 359 ? 19.46401  -12.63140 -29.64392 1.000 38.61060  ? 339 PHE A HE2  1 
ATOM   5188 H  HZ   . PHE A 1 359 ? 17.26764  -13.06536 -29.10462 1.000 33.59236  ? 339 PHE A HZ   1 
ATOM   5189 N  N    . CYS A 1 360 ? 19.13575  -8.87692  -25.96875 1.000 20.15777  ? 340 CYS A N    1 
ATOM   5190 C  CA   . CYS A 1 360 ? 19.81555  -9.47957  -24.81132 1.000 19.08218  ? 340 CYS A CA   1 
ATOM   5191 C  C    . CYS A 1 360 ? 21.02738  -10.31692 -25.20582 1.000 20.43190  ? 340 CYS A C    1 
ATOM   5192 O  O    . CYS A 1 360 ? 20.90820  -11.32996 -25.90955 1.000 21.04246  ? 340 CYS A O    1 
ATOM   5193 C  CB   . CYS A 1 360 ? 18.84739  -10.35564 -24.01766 1.000 19.08212  ? 340 CYS A CB   1 
ATOM   5194 S  SG   . CYS A 1 360 ? 19.59454  -11.17493 -22.62189 1.000 19.07496  ? 340 CYS A SG   1 
ATOM   5195 H  H    . CYS A 1 360 ? 18.27950  -8.95287  -25.94308 1.000 24.21309  ? 340 CYS A H    1 
ATOM   5196 H  HA   . CYS A 1 360 ? 20.11949  -8.74922  -24.24997 1.000 22.92237  ? 340 CYS A HA   1 
ATOM   5197 H  HB2  . CYS A 1 360 ? 18.12687  -9.79909  -23.68300 1.000 22.92230  ? 340 CYS A HB2  1 
ATOM   5198 H  HB3  . CYS A 1 360 ? 18.49216  -11.03957 -24.60668 1.000 22.92230  ? 340 CYS A HB3  1 
ATOM   5199 N  N    . LEU A 1 361 ? 22.19193  -9.95903  -24.64342 1.000 20.45277  ? 341 LEU A N    1 
ATOM   5200 C  CA   . LEU A 1 361 ? 23.41459  -10.69508 -24.95943 1.000 20.84522  ? 341 LEU A CA   1 
ATOM   5201 C  C    . LEU A 1 361 ? 23.41165  -12.09679 -24.34827 1.000 21.07517  ? 341 LEU A C    1 
ATOM   5202 O  O    . LEU A 1 361 ? 24.02791  -13.01091 -24.90390 1.000 23.30262  ? 341 LEU A O    1 
ATOM   5203 C  CB   . LEU A 1 361 ? 24.61717  -9.91145  -24.45944 1.000 23.60952  ? 341 LEU A CB   1 
ATOM   5204 C  CG   . LEU A 1 361 ? 26.01853  -10.46654 -24.82103 1.000 28.43166  ? 341 LEU A CG   1 
ATOM   5205 C  CD1  . LEU A 1 361 ? 26.18812  -10.53325 -26.32441 1.000 32.31823  ? 341 LEU A CD1  1 
ATOM   5206 C  CD2  . LEU A 1 361 ? 27.03530  -9.55775  -24.17844 1.000 31.03984  ? 341 LEU A CD2  1 
ATOM   5207 H  H    . LEU A 1 361 ? 22.29443  -9.30906  -24.08967 1.000 24.56709  ? 341 LEU A H    1 
ATOM   5208 H  HA   . LEU A 1 361 ? 23.48295  -10.79314 -25.92203 1.000 25.03802  ? 341 LEU A HA   1 
ATOM   5209 H  HB2  . LEU A 1 361 ? 24.56397  -9.01576  -24.82795 1.000 28.35518  ? 341 LEU A HB2  1 
ATOM   5210 H  HB3  . LEU A 1 361 ? 24.56838  -9.87533  -23.49134 1.000 28.35518  ? 341 LEU A HB3  1 
ATOM   5211 H  HG   . LEU A 1 361 ? 26.14326  -11.37180 -24.49570 1.000 34.14176  ? 341 LEU A HG   1 
ATOM   5212 H  HD11 . LEU A 1 361 ? 27.10467  -10.77669 -26.52833 1.000 38.80564  ? 341 LEU A HD11 1 
ATOM   5213 H  HD12 . LEU A 1 361 ? 25.58138  -11.20061 -26.68135 1.000 38.80564  ? 341 LEU A HD12 1 
ATOM   5214 H  HD13 . LEU A 1 361 ? 25.98441  -9.66419  -26.70407 1.000 38.80564  ? 341 LEU A HD13 1 
ATOM   5215 H  HD21 . LEU A 1 361 ? 27.92499  -9.89132  -24.37355 1.000 37.27157  ? 341 LEU A HD21 1 
ATOM   5216 H  HD22 . LEU A 1 361 ? 26.93121  -8.66300  -24.53829 1.000 37.27157  ? 341 LEU A HD22 1 
ATOM   5217 H  HD23 . LEU A 1 361 ? 26.88866  -9.54779  -23.21964 1.000 37.27157  ? 341 LEU A HD23 1 
ATOM   5218 N  N    . GLY A 1 362 ? 22.68237  -12.28987 -23.26580 1.000 19.86795  ? 342 GLY A N    1 
ATOM   5219 C  CA   . GLY A 1 362 ? 22.53553  -13.53239 -22.52420 1.000 20.88903  ? 342 GLY A CA   1 
ATOM   5220 C  C    . GLY A 1 362 ? 21.47286  -14.45970 -23.05576 1.000 20.11355  ? 342 GLY A C    1 
ATOM   5221 O  O    . GLY A 1 362 ? 21.22033  -15.49284 -22.43319 1.000 21.44058  ? 342 GLY A O    1 
ATOM   5222 H  H    . GLY A 1 362 ? 22.21964  -11.66053 -22.90607 1.000 23.86531  ? 342 GLY A H    1 
ATOM   5223 H  HA2  . GLY A 1 362 ? 23.38081  -14.00783 -22.54286 1.000 25.09060  ? 342 GLY A HA2  1 
ATOM   5224 H  HA3  . GLY A 1 362 ? 22.31218  -13.32128 -21.60418 1.000 25.09060  ? 342 GLY A HA3  1 
ATOM   5225 N  N    . ASN A 1 363 ? 20.80968  -14.10806 -24.15841 1.000 19.37813  ? 343 ASN A N    1 
ATOM   5226 C  CA   . ASN A 1 363 ? 19.61080  -14.86406 -24.54131 1.000 20.38818  ? 343 ASN A CA   1 
ATOM   5227 C  C    . ASN A 1 363 ? 19.89273  -16.34614 -24.78591 1.000 20.96672  ? 343 ASN A C    1 
ATOM   5228 O  O    . ASN A 1 363 ? 19.03080  -17.18981 -24.48454 1.000 20.96769  ? 343 ASN A O    1 
ATOM   5229 C  CB   . ASN A 1 363 ? 18.94713  -14.24103 -25.76799 1.000 20.26802  ? 343 ASN A CB   1 
ATOM   5230 C  CG   . ASN A 1 363 ? 19.66187  -14.60347 -27.05206 1.000 23.10648  ? 343 ASN A CG   1 
ATOM   5231 O  OD1  . ASN A 1 363 ? 19.30240  -15.59506 -27.72607 1.000 27.11069  ? 343 ASN A OD1  1 
ATOM   5232 N  ND2  . ASN A 1 363 ? 20.70668  -13.85879 -27.39328 1.000 25.33381  ? 343 ASN A ND2  1 
ATOM   5233 H  H    . ASN A 1 363 ? 21.02211  -13.46132 -24.68396 1.000 23.27752  ? 343 ASN A H    1 
ATOM   5234 H  HA   . ASN A 1 363 ? 18.99109  -14.80880 -23.79713 1.000 24.48958  ? 343 ASN A HA   1 
ATOM   5235 H  HB2  . ASN A 1 363 ? 18.03289  -14.55900 -25.83097 1.000 24.34539  ? 343 ASN A HB2  1 
ATOM   5236 H  HB3  . ASN A 1 363 ? 18.95706  -13.27518 -25.67893 1.000 24.34539  ? 343 ASN A HB3  1 
ATOM   5237 H  HD21 . ASN A 1 363 ? 21.14033  -14.03156 -28.11557 1.000 30.42433  ? 343 ASN A HD21 1 
ATOM   5238 H  HD22 . ASN A 1 363 ? 20.94982  -13.20363 -26.89203 1.000 30.42433  ? 343 ASN A HD22 1 
ATOM   5239 N  N    . GLN A 1 364 ? 21.03146  -16.69423 -25.39262 1.000 20.59881  ? 344 GLN A N    1 
ATOM   5240 C  CA   . GLN A 1 364 ? 21.32131  -18.10659 -25.62934 1.000 21.49346  ? 344 GLN A CA   1 
ATOM   5241 C  C    . GLN A 1 364 ? 21.54750  -18.86251 -24.31687 1.000 22.83845  ? 344 GLN A C    1 
ATOM   5242 O  O    . GLN A 1 364 ? 21.12328  -20.02189 -24.16422 1.000 22.58066  ? 344 GLN A O    1 
ATOM   5243 C  CB   . GLN A 1 364 ? 22.56441  -18.25697 -26.52589 1.000 24.16824  ? 344 GLN A CB   1 
ATOM   5244 C  CG   . GLN A 1 364 ? 22.87675  -19.68797 -26.85331 1.000 29.83914  ? 344 GLN A CG   1 
ATOM   5245 C  CD   . GLN A 1 364 ? 24.21454  -19.83843 -27.56179 1.000 35.59026  ? 344 GLN A CD   1 
ATOM   5246 O  OE1  . GLN A 1 364 ? 24.88745  -18.84747 -27.88870 1.000 34.77429  ? 344 GLN A OE1  1 
ATOM   5247 N  NE2  . GLN A 1 364 ? 24.57704  -21.07487 -27.85764 1.000 33.88660  ? 344 GLN A NE2  1 
ATOM   5248 H  H    . GLN A 1 364 ? 21.63461  -16.14676 -25.66848 1.000 24.74233  ? 344 GLN A H    1 
ATOM   5249 H  HA   . GLN A 1 364 ? 20.55871  -18.49496 -26.08596 1.000 25.81592  ? 344 GLN A HA   1 
ATOM   5250 H  HB2  . GLN A 1 364 ? 22.41107  -17.78505 -27.35936 1.000 29.02566  ? 344 GLN A HB2  1 
ATOM   5251 H  HB3  . GLN A 1 364 ? 23.33145  -17.87977 -26.06733 1.000 29.02566  ? 344 GLN A HB3  1 
ATOM   5252 H  HG2  . GLN A 1 364 ? 22.91073  -20.20209 -26.03147 1.000 35.83073  ? 344 GLN A HG2  1 
ATOM   5253 H  HG3  . GLN A 1 364 ? 22.18527  -20.03909 -27.43594 1.000 35.83073  ? 344 GLN A HG3  1 
ATOM   5254 H  HE21 . GLN A 1 364 ? 24.06591  -21.73435 -27.64924 1.000 40.68768  ? 344 GLN A HE21 1 
ATOM   5255 H  HE22 . GLN A 1 364 ? 25.32399  -21.21973 -28.25851 1.000 40.68768  ? 344 GLN A HE22 1 
ATOM   5256 N  N    . LEU A 1 365 ? 22.26906  -18.25082 -23.37973 1.000 21.03915  ? 345 LEU A N    1 
ATOM   5257 C  CA   . LEU A 1 365 ? 22.51030  -18.89387 -22.09399 1.000 22.52514  ? 345 LEU A CA   1 
ATOM   5258 C  C    . LEU A 1 365 ? 21.21419  -19.07404 -21.31654 1.000 20.76806  ? 345 LEU A C    1 
ATOM   5259 O  O    . LEU A 1 365 ? 20.96952  -20.14592 -20.73661 1.000 21.19854  ? 345 LEU A O    1 
ATOM   5260 C  CB   . LEU A 1 365 ? 23.47894  -18.06034 -21.27163 1.000 21.26132  ? 345 LEU A CB   1 
ATOM   5261 C  CG   . LEU A 1 365 ? 23.79167  -18.57157 -19.88387 1.000 22.76333  ? 345 LEU A CG   1 
ATOM   5262 C  CD1  . LEU A 1 365 ? 24.43234  -19.94395 -19.88933 1.000 24.26285  ? 345 LEU A CD1  1 
ATOM   5263 C  CD2  . LEU A 1 365 ? 24.71393  -17.58848 -19.17318 1.000 26.34047  ? 345 LEU A CD2  1 
ATOM   5264 H  H    . LEU A 1 365 ? 22.62558  -17.47262 -23.46279 1.000 25.27074  ? 345 LEU A H    1 
ATOM   5265 H  HA   . LEU A 1 365 ? 22.90302  -19.76601 -22.25538 1.000 27.05393  ? 345 LEU A HA   1 
ATOM   5266 H  HB2  . LEU A 1 365 ? 24.31893  -18.01125 -21.75423 1.000 25.53735  ? 345 LEU A HB2  1 
ATOM   5267 H  HB3  . LEU A 1 365 ? 23.10181  -17.17234 -21.17091 1.000 25.53735  ? 345 LEU A HB3  1 
ATOM   5268 H  HG   . LEU A 1 365 ? 22.95100  -18.65434 -19.40708 1.000 27.33975  ? 345 LEU A HG   1 
ATOM   5269 H  HD11 . LEU A 1 365 ? 24.68713  -20.17713 -18.98291 1.000 29.13918  ? 345 LEU A HD11 1 
ATOM   5270 H  HD12 . LEU A 1 365 ? 23.79330  -20.58943 -20.22974 1.000 29.13918  ? 345 LEU A HD12 1 
ATOM   5271 H  HD13 . LEU A 1 365 ? 25.21735  -19.92373 -20.45877 1.000 29.13918  ? 345 LEU A HD13 1 
ATOM   5272 H  HD21 . LEU A 1 365 ? 24.89749  -17.91737 -18.27929 1.000 31.63232  ? 345 LEU A HD21 1 
ATOM   5273 H  HD22 . LEU A 1 365 ? 25.54111  -17.51282 -19.67414 1.000 31.63232  ? 345 LEU A HD22 1 
ATOM   5274 H  HD23 . LEU A 1 365 ? 24.27659  -16.72405 -19.12426 1.000 31.63232  ? 345 LEU A HD23 1 
ATOM   5275 N  N    . ALA A 1 366 ? 20.34284  -18.05389 -21.32958 1.000 20.22077  ? 346 ALA A N    1 
ATOM   5276 C  CA   . ALA A 1 366 ? 19.04590  -18.17595 -20.66753 1.000 19.38537  ? 346 ALA A CA   1 
ATOM   5277 C  C    . ALA A 1 366 ? 18.23212  -19.32534 -21.29392 1.000 18.95471  ? 346 ALA A C    1 
ATOM   5278 O  O    . ALA A 1 366 ? 17.62143  -20.14049 -20.57745 1.000 18.70546  ? 346 ALA A O    1 
ATOM   5279 C  CB   . ALA A 1 366 ? 18.29698  -16.85480 -20.78417 1.000 20.30241  ? 346 ALA A CB   1 
ATOM   5280 H  H    . ALA A 1 366 ? 20.48007  -17.29472 -21.70962 1.000 24.28868  ? 346 ALA A H    1 
ATOM   5281 H  HA   . ALA A 1 366 ? 19.17224  -18.37144 -19.72587 1.000 23.28621  ? 346 ALA A HA   1 
ATOM   5282 H  HB1  . ALA A 1 366 ? 17.42074  -16.95170 -20.37955 1.000 24.38666  ? 346 ALA A HB1  1 
ATOM   5283 H  HB2  . ALA A 1 366 ? 18.79970  -16.16505 -20.32329 1.000 24.38666  ? 346 ALA A HB2  1 
ATOM   5284 H  HB3  . ALA A 1 366 ? 18.20466  -16.62587 -21.72224 1.000 24.38666  ? 346 ALA A HB3  1 
ATOM   5285 N  N    . ARG A 1 367 ? 18.18188  -19.36919 -22.63475 1.000 19.74995  ? 347 ARG A N    1 
ATOM   5286 C  CA   . ARG A 1 367 ? 17.43634  -20.42921 -23.31783 1.000 20.66167  ? 347 ARG A CA   1 
ATOM   5287 C  C    . ARG A 1 367 ? 17.99961  -21.80585 -22.96632 1.000 22.17154  ? 347 ARG A C    1 
ATOM   5288 O  O    . ARG A 1 367 ? 17.24062  -22.76714 -22.77546 1.000 20.87559  ? 347 ARG A O    1 
ATOM   5289 C  CB   . ARG A 1 367 ? 17.44958  -20.19964 -24.82638 1.000 21.48339  ? 347 ARG A CB   1 
ATOM   5290 C  CG   . ARG A 1 367 ? 16.44403  -19.11474 -25.22353 1.000 20.53540  ? 347 ARG A CG   1 
ATOM   5291 C  CD   . ARG A 1 367 ? 16.67063  -18.70832 -26.70611 1.000 23.71375  ? 347 ARG A CD   1 
ATOM   5292 N  NE   . ARG A 1 367 ? 15.51346  -17.99675 -27.22252 1.000 23.27596  ? 347 ARG A NE   1 
ATOM   5293 C  CZ   . ARG A 1 367 ? 15.52068  -16.83559 -27.86001 1.000 27.91077  ? 347 ARG A CZ   1 
ATOM   5294 N  NH1  . ARG A 1 367 ? 16.64083  -16.17514 -28.10689 1.000 29.65541  ? 347 ARG A NH1  1 
ATOM   5295 N  NH2  . ARG A 1 367 ? 14.36702  -16.33989 -28.29560 1.000 26.02493  ? 347 ARG A NH2  1 
ATOM   5296 H  H    . ARG A 1 367 ? 18.56472  -18.80620 -23.16017 1.000 23.72371  ? 347 ARG A H    1 
ATOM   5297 H  HA   . ARG A 1 367 ? 16.51086  -20.40121 -23.02871 1.000 24.81777  ? 347 ARG A HA   1 
ATOM   5298 H  HB2  . ARG A 1 367 ? 18.33498  -19.91470 -25.10164 1.000 25.80383  ? 347 ARG A HB2  1 
ATOM   5299 H  HB3  . ARG A 1 367 ? 17.20995  -21.02279 -25.28014 1.000 25.80383  ? 347 ARG A HB3  1 
ATOM   5300 H  HG2  . ARG A 1 367 ? 15.54033  -19.45375 -25.12712 1.000 24.66625  ? 347 ARG A HG2  1 
ATOM   5301 H  HG3  . ARG A 1 367 ? 16.56655  -18.33266 -24.66295 1.000 24.66625  ? 347 ARG A HG3  1 
ATOM   5302 H  HD2  . ARG A 1 367 ? 17.44439  -18.12672 -26.76876 1.000 28.48026  ? 347 ARG A HD2  1 
ATOM   5303 H  HD3  . ARG A 1 367 ? 16.80929  -19.50396 -27.24336 1.000 28.48026  ? 347 ARG A HD3  1 
ATOM   5304 H  HE   . ARG A 1 367 ? 14.74659  -18.36688 -27.10207 1.000 27.95491  ? 347 ARG A HE   1 
ATOM   5305 H  HH11 . ARG A 1 367 ? 17.39572  -16.49811 -27.85110 1.000 35.61025  ? 347 ARG A HH11 1 
ATOM   5306 H  HH12 . ARG A 1 367 ? 16.61375  -15.42305 -28.52310 1.000 35.61025  ? 347 ARG A HH12 1 
ATOM   5307 H  HH21 . ARG A 1 367 ? 13.63548  -16.77171 -28.16151 1.000 31.25368  ? 347 ARG A HH21 1 
ATOM   5308 H  HH22 . ARG A 1 367 ? 14.35205  -15.58732 -28.71155 1.000 31.25368  ? 347 ARG A HH22 1 
ATOM   5309 N  N    . LEU A 1 368 ? 19.32681  -21.93414 -22.89509 1.000 19.42072  ? 348 LEU A N    1 
ATOM   5310 C  CA   . LEU A 1 368 ? 19.92977  -23.21530 -22.56016 1.000 20.41854  ? 348 LEU A CA   1 
ATOM   5311 C  C    . LEU A 1 368 ? 19.56354  -23.65077 -21.13212 1.000 20.06486  ? 348 LEU A C    1 
ATOM   5312 O  O    . LEU A 1 368 ? 19.22635  -24.82781 -20.89458 1.000 21.23623  ? 348 LEU A O    1 
ATOM   5313 C  CB   . LEU A 1 368 ? 21.44289  -23.11415 -22.76750 1.000 21.59992  ? 348 LEU A CB   1 
ATOM   5314 C  CG   . LEU A 1 368 ? 22.25738  -24.38564 -22.60273 1.000 23.78713  ? 348 LEU A CG   1 
ATOM   5315 C  CD1  . LEU A 1 368 ? 21.75538  -25.46807 -23.52710 1.000 25.10111  ? 348 LEU A CD1  1 
ATOM   5316 C  CD2  . LEU A 1 368 ? 23.74630  -24.12595 -22.82776 1.000 24.65082  ? 348 LEU A CD2  1 
ATOM   5317 H  H    . LEU A 1 368 ? 19.89055  -21.29998 -23.03522 1.000 23.32862  ? 348 LEU A H    1 
ATOM   5318 H  HA   . LEU A 1 368 ? 19.59500  -23.90900 -23.14975 1.000 24.52601  ? 348 LEU A HA   1 
ATOM   5319 H  HB2  . LEU A 1 368 ? 21.59820  -22.79578 -23.67050 1.000 25.94367  ? 348 LEU A HB2  1 
ATOM   5320 H  HB3  . LEU A 1 368 ? 21.78833  -22.47384 -22.12596 1.000 25.94367  ? 348 LEU A HB3  1 
ATOM   5321 H  HG   . LEU A 1 368 ? 22.15233  -24.69872 -21.69068 1.000 28.56832  ? 348 LEU A HG   1 
ATOM   5322 H  HD11 . LEU A 1 368 ? 22.35576  -26.22839 -23.47847 1.000 30.14509  ? 348 LEU A HD11 1 
ATOM   5323 H  HD12 . LEU A 1 368 ? 20.86418  -25.73205 -23.24966 1.000 30.14509  ? 348 LEU A HD12 1 
ATOM   5324 H  HD13 . LEU A 1 368 ? 21.73111  -25.12321 -24.43341 1.000 30.14509  ? 348 LEU A HD13 1 
ATOM   5325 H  HD21 . LEU A 1 368 ? 24.23436  -24.95423 -22.69875 1.000 29.60475  ? 348 LEU A HD21 1 
ATOM   5326 H  HD22 . LEU A 1 368 ? 23.87718  -23.80242 -23.73280 1.000 29.60475  ? 348 LEU A HD22 1 
ATOM   5327 H  HD23 . LEU A 1 368 ? 24.05048  -23.46019 -22.19126 1.000 29.60475  ? 348 LEU A HD23 1 
ATOM   5328 N  N    . GLU A 1 369 ? 19.63105  -22.72711 -20.15998 1.000 20.03609  ? 349 GLU A N    1 
ATOM   5329 C  CA   . GLU A 1 369 ? 19.23831  -23.05417 -18.79248 1.000 21.15412  ? 349 GLU A CA   1 
ATOM   5330 C  C    . GLU A 1 369 ? 17.77911  -23.48745 -18.74009 1.000 21.28907  ? 349 GLU A C    1 
ATOM   5331 O  O    . GLU A 1 369 ? 17.42481  -24.48035 -18.08465 1.000 20.47797  ? 349 GLU A O    1 
ATOM   5332 C  CB   . GLU A 1 369 ? 19.46704  -21.85965 -17.86385 1.000 21.62177  ? 349 GLU A CB   1 
ATOM   5333 C  CG   . GLU A 1 369 ? 20.90237  -21.48889 -17.64707 1.000 22.10678  ? 349 GLU A CG   1 
ATOM   5334 C  CD   . GLU A 1 369 ? 21.11926  -20.21239 -16.87575 1.000 26.99721  ? 349 GLU A CD   1 
ATOM   5335 O  OE1  . GLU A 1 369 ? 20.15990  -19.59975 -16.40419 1.000 25.60353  ? 349 GLU A OE1  1 
ATOM   5336 O  OE2  . GLU A 1 369 ? 22.29304  -19.79918 -16.74918 1.000 26.49841  ? 349 GLU A OE2  1 
ATOM   5337 H  H    . GLU A 1 369 ? 19.89771  -21.91692 -20.26995 1.000 24.06707  ? 349 GLU A H    1 
ATOM   5338 H  HA   . GLU A 1 369 ? 19.79503  -23.78459 -18.48030 1.000 25.40871  ? 349 GLU A HA   1 
ATOM   5339 H  HB2  . GLU A 1 369 ? 19.02153  -21.08627 -18.24374 1.000 25.96988  ? 349 GLU A HB2  1 
ATOM   5340 H  HB3  . GLU A 1 369 ? 19.08686  -22.06859 -16.99626 1.000 25.96988  ? 349 GLU A HB3  1 
ATOM   5341 H  HG2  . GLU A 1 369 ? 21.33361  -22.20374 -17.15318 1.000 26.55190  ? 349 GLU A HG2  1 
ATOM   5342 H  HG3  . GLU A 1 369 ? 21.32643  -21.38100 -18.51277 1.000 26.55190  ? 349 GLU A HG3  1 
ATOM   5343 N  N    . LEU A 1 370 ? 16.91425  -22.74523 -19.43016 1.000 19.62588  ? 350 LEU A N    1 
ATOM   5344 C  CA   . LEU A 1 370 ? 15.48729  -23.06985 -19.45240 1.000 20.42096  ? 350 LEU A CA   1 
ATOM   5345 C  C    . LEU A 1 370 ? 15.24676  -24.46601 -20.02428 1.000 20.55872  ? 350 LEU A C    1 
ATOM   5346 O  O    . LEU A 1 370 ? 14.44568  -25.24745 -19.47551 1.000 19.90063  ? 350 LEU A O    1 
ATOM   5347 C  CB   . LEU A 1 370 ? 14.70242  -22.01890 -20.24088 1.000 20.56383  ? 350 LEU A CB   1 
ATOM   5348 C  CG   . LEU A 1 370 ? 14.64445  -20.63261 -19.57626 1.000 21.31715  ? 350 LEU A CG   1 
ATOM   5349 C  CD1  . LEU A 1 370 ? 14.16161  -19.55612 -20.53425 1.000 23.69332  ? 350 LEU A CD1  1 
ATOM   5350 C  CD2  . LEU A 1 370 ? 13.73158  -20.66727 -18.35337 1.000 25.24657  ? 350 LEU A CD2  1 
ATOM   5351 H  H    . LEU A 1 370 ? 17.12523  -22.05133 -19.89230 1.000 23.57482  ? 350 LEU A H    1 
ATOM   5352 H  HA   . LEU A 1 370 ? 15.15948  -23.05510 -18.53959 1.000 24.52891  ? 350 LEU A HA   1 
ATOM   5353 H  HB2  . LEU A 1 370 ? 15.11978  -21.91049 -21.10976 1.000 24.70036  ? 350 LEU A HB2  1 
ATOM   5354 H  HB3  . LEU A 1 370 ? 13.79039  -22.33148 -20.34759 1.000 24.70036  ? 350 LEU A HB3  1 
ATOM   5355 H  HG   . LEU A 1 370 ? 15.54620  -20.40181 -19.30336 1.000 25.60435  ? 350 LEU A HG   1 
ATOM   5356 H  HD11 . LEU A 1 370 ? 14.13140  -18.70714 -20.06603 1.000 28.45575  ? 350 LEU A HD11 1 
ATOM   5357 H  HD12 . LEU A 1 370 ? 14.77690  -19.49975 -21.28201 1.000 28.45575  ? 350 LEU A HD12 1 
ATOM   5358 H  HD13 . LEU A 1 370 ? 13.27555  -19.79039 -20.85191 1.000 28.45575  ? 350 LEU A HD13 1 
ATOM   5359 H  HD21 . LEU A 1 370 ? 13.11990  -19.91557 -18.39449 1.000 30.31964  ? 350 LEU A HD21 1 
ATOM   5360 H  HD22 . LEU A 1 370 ? 13.23339  -21.49957 -18.35466 1.000 30.31964  ? 350 LEU A HD22 1 
ATOM   5361 H  HD23 . LEU A 1 370 ? 14.27485  -20.60820 -17.55196 1.000 30.31964  ? 350 LEU A HD23 1 
ATOM   5362 N  N    . SER A 1 371 ? 15.91862  -24.78808 -21.13605 1.000 18.83096  ? 351 SER A N    1 
ATOM   5363 C  CA   A SER A 1 371 ? 15.73507  -26.08861 -21.77144 0.499 22.04147  ? 351 SER A CA   1 
ATOM   5364 C  CA   B SER A 1 371 ? 15.73881  -26.08417 -21.77525 0.501 22.05245  ? 351 SER A CA   1 
ATOM   5365 C  C    . SER A 1 371 ? 16.23199  -27.21305 -20.88322 1.000 24.26398  ? 351 SER A C    1 
ATOM   5366 O  O    . SER A 1 371 ? 15.54797  -28.22746 -20.68989 1.000 23.52561  ? 351 SER A O    1 
ATOM   5367 C  CB   A SER A 1 371 ? 16.44307  -26.12613 -23.12025 0.499 24.12766  ? 351 SER A CB   1 
ATOM   5368 C  CB   B SER A 1 371 ? 16.48553  -26.09127 -23.10182 0.501 24.10111  ? 351 SER A CB   1 
ATOM   5369 O  OG   A SER A 1 371 ? 16.08467  -25.02503 -23.92476 0.499 27.45575  ? 351 SER A OG   1 
ATOM   5370 O  OG   B SER A 1 371 ? 16.25983  -27.30289 -23.78888 0.501 26.52285  ? 351 SER A OG   1 
ATOM   5371 H  H    . SER A 1 371 ? 16.48083  -24.27617 -21.53788 1.000 22.62091  ? 351 SER A H    1 
ATOM   5372 H  HA   . SER A 1 371 ? 14.78629  -26.21967 -21.92481 1.000 26.48671  ? 351 SER A HA   1 
ATOM   5373 H  HB2  A SER A 1 371 ? 17.40134  -26.10592 -22.97122 0.499 28.97696  ? 351 SER A HB2  1 
ATOM   5374 H  HB2  B SER A 1 371 ? 16.17016  -25.35378 -23.64731 0.501 28.94510  ? 351 SER A HB2  1 
ATOM   5375 H  HB3  A SER A 1 371 ? 16.19607  -26.94344 -23.58057 0.499 28.97696  ? 351 SER A HB3  1 
ATOM   5376 H  HB3  B SER A 1 371 ? 17.43564  -25.99539 -22.93154 0.501 28.94510  ? 351 SER A HB3  1 
ATOM   5377 H  HG   A SER A 1 371 ? 16.52837  -25.03382 -24.63796 0.499 32.97066  ? 351 SER A HG   1 
ATOM   5378 H  HG   B SER A 1 371 ? 15.46015  -27.34465 -24.04257 0.501 31.85118  ? 351 SER A HG   1 
ATOM   5379 N  N    . LEU A 1 372 ? 17.42002  -27.05431 -20.32044 1.000 22.69300  ? 352 LEU A N    1 
ATOM   5380 C  CA   . LEU A 1 372 ? 17.99240  -28.16036 -19.56911 1.000 23.02175  ? 352 LEU A CA   1 
ATOM   5381 C  C    . LEU A 1 372 ? 17.22344  -28.42931 -18.27269 1.000 23.02588  ? 352 LEU A C    1 
ATOM   5382 O  O    . LEU A 1 372 ? 17.01632  -29.59566 -17.91531 1.000 23.80174  ? 352 LEU A O    1 
ATOM   5383 C  CB   . LEU A 1 372 ? 19.47635  -27.88275 -19.29436 1.000 24.98341  ? 352 LEU A CB   1 
ATOM   5384 C  CG   . LEU A 1 372 ? 20.33492  -27.94760 -20.56115 1.000 23.60829  ? 352 LEU A CG   1 
ATOM   5385 C  CD1  . LEU A 1 372 ? 21.72483  -27.42658 -20.21189 1.000 24.57920  ? 352 LEU A CD1  1 
ATOM   5386 C  CD2  . LEU A 1 372 ? 20.41870  -29.36564 -21.14472 1.000 28.14539  ? 352 LEU A CD2  1 
ATOM   5387 H  H    . LEU A 1 372 ? 17.89993  -26.34157 -20.35648 1.000 27.25537  ? 352 LEU A H    1 
ATOM   5388 H  HA   . LEU A 1 372 ? 17.93287  -28.96813 -20.10282 1.000 27.64986  ? 352 LEU A HA   1 
ATOM   5389 H  HB2  . LEU A 1 372 ? 19.56585  -26.99449 -18.91505 1.000 30.00386  ? 352 LEU A HB2  1 
ATOM   5390 H  HB3  . LEU A 1 372 ? 19.81057  -28.54542 -18.66980 1.000 30.00386  ? 352 LEU A HB3  1 
ATOM   5391 H  HG   . LEU A 1 372 ? 19.93036  -27.40224 -21.25384 1.000 28.35371  ? 352 LEU A HG   1 
ATOM   5392 H  HD11 . LEU A 1 372 ? 22.24969  -27.35758 -21.02470 1.000 29.51880  ? 352 LEU A HD11 1 
ATOM   5393 H  HD12 . LEU A 1 372 ? 21.63997  -26.55351 -19.79783 1.000 29.51880  ? 352 LEU A HD12 1 
ATOM   5394 H  HD13 . LEU A 1 372 ? 22.14837  -28.04493 -19.59614 1.000 29.51880  ? 352 LEU A HD13 1 
ATOM   5395 H  HD21 . LEU A 1 372 ? 21.13989  -29.39842 -21.79257 1.000 33.79823  ? 352 LEU A HD21 1 
ATOM   5396 H  HD22 . LEU A 1 372 ? 20.59122  -29.99338 -20.42564 1.000 33.79823  ? 352 LEU A HD22 1 
ATOM   5397 H  HD23 . LEU A 1 372 ? 19.57667  -29.57992 -21.57597 1.000 33.79823  ? 352 LEU A HD23 1 
ATOM   5398 N  N    . MET A 1 373 ? 16.79990  -27.38286 -17.55236 1.000 21.87530  ? 353 MET A N    1 
ATOM   5399 C  CA   . MET A 1 373 ? 16.05873  -27.62224 -16.31746 1.000 21.91717  ? 353 MET A CA   1 
ATOM   5400 C  C    . MET A 1 373 ? 14.67146  -28.17394 -16.62265 1.000 21.66884  ? 353 MET A C    1 
ATOM   5401 O  O    . MET A 1 373 ? 14.21234  -29.11498 -15.96409 1.000 21.92523  ? 353 MET A O    1 
ATOM   5402 C  CB   . MET A 1 373 ? 15.94264  -26.34900 -15.48253 1.000 23.80133  ? 353 MET A CB   1 
ATOM   5403 C  CG   . MET A 1 373 ? 15.15802  -26.51841 -14.17766 1.000 22.49120  ? 353 MET A CG   1 
ATOM   5404 S  SD   . MET A 1 373 ? 15.73093  -27.83240 -13.05240 1.000 25.45343  ? 353 MET A SD   1 
ATOM   5405 C  CE   . MET A 1 373 ? 16.88634  -26.90513 -12.03337 1.000 27.88734  ? 353 MET A CE   1 
ATOM   5406 H  H    . MET A 1 373 ? 16.92576  -26.55595 -17.75233 1.000 26.27412  ? 353 MET A H    1 
ATOM   5407 H  HA   . MET A 1 373 ? 16.56061  -28.26274 -15.78947 1.000 26.32437  ? 353 MET A HA   1 
ATOM   5408 H  HB2  . MET A 1 373 ? 16.83533  -26.04807 -15.25136 1.000 28.58536  ? 353 MET A HB2  1 
ATOM   5409 H  HB3  . MET A 1 373 ? 15.49095  -25.67252 -16.01097 1.000 28.58536  ? 353 MET A HB3  1 
ATOM   5410 H  HG2  . MET A 1 373 ? 15.20479  -25.68320 -13.68661 1.000 27.01320  ? 353 MET A HG2  1 
ATOM   5411 H  HG3  . MET A 1 373 ? 14.23632  -26.71934 -14.40347 1.000 27.01320  ? 353 MET A HG3  1 
ATOM   5412 H  HE1  . MET A 1 373 ? 17.28456  -27.50413 -11.38258 1.000 33.48857  ? 353 MET A HE1  1 
ATOM   5413 H  HE2  . MET A 1 373 ? 17.57625  -26.52806 -12.60148 1.000 33.48857  ? 353 MET A HE2  1 
ATOM   5414 H  HE3  . MET A 1 373 ? 16.40699  -26.19464 -11.57913 1.000 33.48857  ? 353 MET A HE3  1 
ATOM   5415 N  N    . THR A 1 374 ? 14.00579  -27.63318 -17.64694 1.000 22.27329  ? 354 THR A N    1 
ATOM   5416 C  CA   . THR A 1 374 ? 12.65107  -28.09318 -17.94958 1.000 20.62729  ? 354 THR A CA   1 
ATOM   5417 C  C    . THR A 1 374 ? 12.66351  -29.54183 -18.43422 1.000 23.06297  ? 354 THR A C    1 
ATOM   5418 O  O    . THR A 1 374 ? 11.83142  -30.34457 -18.00330 1.000 22.81091  ? 354 THR A O    1 
ATOM   5419 C  CB   . THR A 1 374 ? 12.00517  -27.15231 -18.97921 1.000 20.01338  ? 354 THR A CB   1 
ATOM   5420 O  OG1  . THR A 1 374 ? 11.92692  -25.81997 -18.45541 1.000 19.92868  ? 354 THR A OG1  1 
ATOM   5421 C  CG2  . THR A 1 374 ? 10.56219  -27.59526 -19.33744 1.000 22.86947  ? 354 THR A CG2  1 
ATOM   5422 H  H    . THR A 1 374 ? 14.30729  -27.01729 -18.16596 1.000 26.75171  ? 354 THR A H    1 
ATOM   5423 H  HA   . THR A 1 374 ? 12.10659  -28.06220 -17.14741 1.000 24.77651  ? 354 THR A HA   1 
ATOM   5424 H  HB   . THR A 1 374 ? 12.55263  -27.17491 -19.77963 1.000 24.03982  ? 354 THR A HB   1 
ATOM   5425 H  HG1  . THR A 1 374 ? 12.69940  -25.51167 -18.33780 1.000 23.93818  ? 354 THR A HG1  1 
ATOM   5426 H  HG21 . THR A 1 374 ? 10.13542  -26.92095 -19.88886 1.000 27.46712  ? 354 THR A HG21 1 
ATOM   5427 H  HG22 . THR A 1 374 ? 10.58391  -28.43334 -19.82534 1.000 27.46712  ? 354 THR A HG22 1 
ATOM   5428 H  HG23 . THR A 1 374 ? 10.04151  -27.71567 -18.52794 1.000 27.46712  ? 354 THR A HG23 1 
ATOM   5429 N  N    . GLU A 1 375 ? 13.64839  -29.93252 -19.25183 1.000 21.59556  ? 355 GLU A N    1 
ATOM   5430 C  CA   . GLU A 1 375 ? 13.77508  -31.33032 -19.65323 1.000 24.11825  ? 355 GLU A CA   1 
ATOM   5431 C  C    . GLU A 1 375 ? 13.87348  -32.24724 -18.43810 1.000 24.07077  ? 355 GLU A C    1 
ATOM   5432 O  O    . GLU A 1 375 ? 13.23620  -33.31443 -18.37743 1.000 27.06857  ? 355 GLU A O    1 
ATOM   5433 C  CB   . GLU A 1 375 ? 15.01455  -31.48801 -20.55540 1.000 28.17408  ? 355 GLU A CB   1 
ATOM   5434 C  CG   . GLU A 1 375 ? 15.32116  -32.85092 -21.05649 1.000 36.92356  ? 355 GLU A CG   1 
ATOM   5435 C  CD   . GLU A 1 375 ? 16.52705  -32.84109 -22.03830 1.000 62.23321  ? 355 GLU A CD   1 
ATOM   5436 O  OE1  . GLU A 1 375 ? 17.55283  -32.13944 -21.77067 1.000 46.54089  ? 355 GLU A OE1  1 
ATOM   5437 O  OE2  . GLU A 1 375 ? 16.45219  -33.54618 -23.07145 1.000 73.39036  ? 355 GLU A OE2  1 
ATOM   5438 H  H    . GLU A 1 375 ? 14.24765  -29.41186 -19.58260 1.000 25.93843  ? 355 GLU A H    1 
ATOM   5439 H  HA   . GLU A 1 375 ? 12.98964  -31.59345 -20.15795 1.000 28.96566  ? 355 GLU A HA   1 
ATOM   5440 H  HB2  . GLU A 1 375 ? 14.89015  -30.92350 -21.33434 1.000 33.83266  ? 355 GLU A HB2  1 
ATOM   5441 H  HB3  . GLU A 1 375 ? 15.78930  -31.19269 -20.05197 1.000 33.83266  ? 355 GLU A HB3  1 
ATOM   5442 H  HG2  . GLU A 1 375 ? 15.54262  -33.42577 -20.30721 1.000 44.33204  ? 355 GLU A HG2  1 
ATOM   5443 H  HG3  . GLU A 1 375 ? 14.54823  -33.20126 -21.52631 1.000 44.33204  ? 355 GLU A HG3  1 
ATOM   5444 N  N    . ARG A 1 376 ? 14.64946  -31.82948 -17.44541 1.000 24.71667  ? 356 ARG A N    1 
ATOM   5445 C  CA   . ARG A 1 376 ? 14.85679  -32.69504 -16.29779 1.000 24.79649  ? 356 ARG A CA   1 
ATOM   5446 C  C    . ARG A 1 376 ? 13.66090  -32.71030 -15.34937 1.000 24.72020  ? 356 ARG A C    1 
ATOM   5447 O  O    . ARG A 1 376 ? 13.34913  -33.76914 -14.78844 1.000 27.14801  ? 356 ARG A O    1 
ATOM   5448 C  CB   . ARG A 1 376 ? 16.12854  -32.28083 -15.57233 1.000 25.92215  ? 356 ARG A CB   1 
ATOM   5449 C  CG   . ARG A 1 376 ? 17.37215  -32.94888 -16.21143 1.000 32.32224  ? 356 ARG A CG   1 
ATOM   5450 C  CD   . ARG A 1 376 ? 18.62716  -32.15228 -16.05138 1.000 29.35365  ? 356 ARG A CD   1 
ATOM   5451 N  NE   . ARG A 1 376 ? 19.67304  -32.81856 -16.81851 1.000 32.42433  ? 356 ARG A NE   1 
ATOM   5452 C  CZ   . ARG A 1 376 ? 19.77517  -32.69652 -18.13855 1.000 34.04514  ? 356 ARG A CZ   1 
ATOM   5453 N  NH1  . ARG A 1 376 ? 19.01543  -31.84402 -18.81995 1.000 33.39705  ? 356 ARG A NH1  1 
ATOM   5454 N  NH2  . ARG A 1 376 ? 20.63611  -33.46097 -18.79559 1.000 35.70945  ? 356 ARG A NH2  1 
ATOM   5455 H  H    . ARG A 1 376 ? 15.05470  -31.07158 -17.41435 1.000 29.68376  ? 356 ARG A H    1 
ATOM   5456 H  HA   . ARG A 1 376 ? 14.96970  -33.60563 -16.61240 1.000 29.77955  ? 356 ARG A HA   1 
ATOM   5457 H  HB2  . ARG A 1 376 ? 16.23299  -31.31809 -15.62816 1.000 31.13035  ? 356 ARG A HB2  1 
ATOM   5458 H  HB3  . ARG A 1 376 ? 16.07433  -32.55536 -14.64357 1.000 31.13035  ? 356 ARG A HB3  1 
ATOM   5459 H  HG2  . ARG A 1 376 ? 17.51406  -33.81225 -15.79268 1.000 38.81045  ? 356 ARG A HG2  1 
ATOM   5460 H  HG3  . ARG A 1 376 ? 17.21309  -33.06307 -17.16146 1.000 38.81045  ? 356 ARG A HG3  1 
ATOM   5461 H  HD2  . ARG A 1 376 ? 18.50052  -31.25363 -16.39385 1.000 35.24815  ? 356 ARG A HD2  1 
ATOM   5462 H  HD3  . ARG A 1 376 ? 18.88629  -32.11788 -15.11727 1.000 35.24815  ? 356 ARG A HD3  1 
ATOM   5463 H  HE   . ARG A 1 376 ? 20.24445  -33.30814 -16.40209 1.000 38.93296  ? 356 ARG A HE   1 
ATOM   5464 H  HH11 . ARG A 1 376 ? 18.44102  -31.35508 -18.40693 1.000 40.10023  ? 356 ARG A HH11 1 
ATOM   5465 H  HH12 . ARG A 1 376 ? 19.09849  -31.78163 -19.67365 1.000 40.10023  ? 356 ARG A HH12 1 
ATOM   5466 H  HH21 . ARG A 1 376 ? 21.12098  -34.02811 -18.36797 1.000 42.87510  ? 356 ARG A HH21 1 
ATOM   5467 H  HH22 . ARG A 1 376 ? 20.70977  -33.38977 -19.64947 1.000 42.87510  ? 356 ARG A HH22 1 
ATOM   5468 N  N    . VAL A 1 377 ? 12.98829  -31.57271 -15.18899 1.000 24.11918  ? 357 VAL A N    1 
ATOM   5469 C  CA   . VAL A 1 377 ? 11.76602  -31.51138 -14.37959 1.000 23.46126  ? 357 VAL A CA   1 
ATOM   5470 C  C    . VAL A 1 377 ? 10.70322  -32.42341 -14.98712 1.000 25.45273  ? 357 VAL A C    1 
ATOM   5471 O  O    . VAL A 1 377 ? 10.07328  -33.22428 -14.29013 1.000 25.28717  ? 357 VAL A O    1 
ATOM   5472 C  CB   . VAL A 1 377 ? 11.27958  -30.05635 -14.26796 1.000 23.97870  ? 357 VAL A CB   1 
ATOM   5473 C  CG1  . VAL A 1 377 ? 9.83618   -29.99628 -13.73127 1.000 27.88498  ? 357 VAL A CG1  1 
ATOM   5474 C  CG2  . VAL A 1 377 ? 12.20112  -29.28958 -13.31907 1.000 24.15940  ? 357 VAL A CG2  1 
ATOM   5475 H  H    . VAL A 1 377 ? 13.21535  -30.81964 -15.53673 1.000 28.96678  ? 357 VAL A H    1 
ATOM   5476 H  HA   . VAL A 1 377 ? 11.95651  -31.82811 -13.48277 1.000 28.17728  ? 357 VAL A HA   1 
ATOM   5477 H  HB   . VAL A 1 377 ? 11.29479  -29.65120 -15.14916 1.000 28.79821  ? 357 VAL A HB   1 
ATOM   5478 H  HG11 . VAL A 1 377 ? 9.63468   -29.08457 -13.46841 1.000 33.48573  ? 357 VAL A HG11 1 
ATOM   5479 H  HG12 . VAL A 1 377 ? 9.22718   -30.28122 -14.43042 1.000 33.48573  ? 357 VAL A HG12 1 
ATOM   5480 H  HG13 . VAL A 1 377 ? 9.75936   -30.58610 -12.96504 1.000 33.48573  ? 357 VAL A HG13 1 
ATOM   5481 H  HG21 . VAL A 1 377 ? 11.92902  -28.35877 -13.29814 1.000 29.01504  ? 357 VAL A HG21 1 
ATOM   5482 H  HG22 . VAL A 1 377 ? 12.13149  -29.67460 -12.43148 1.000 29.01504  ? 357 VAL A HG22 1 
ATOM   5483 H  HG23 . VAL A 1 377 ? 13.11390  -29.36025 -13.63961 1.000 29.01504  ? 357 VAL A HG23 1 
ATOM   5484 N  N    . LEU A 1 378 ? 10.52600  -32.35367 -16.31664 1.000 24.16927  ? 358 LEU A N    1 
ATOM   5485 C  CA   . LEU A 1 378 ? 9.55414   -33.21909 -16.98779 1.000 27.36717  ? 358 LEU A CA   1 
ATOM   5486 C  C    . LEU A 1 378 ? 9.85556   -34.69466 -16.75145 1.000 28.84469  ? 358 LEU A C    1 
ATOM   5487 O  O    . LEU A 1 378 ? 8.93847   -35.51559 -16.58047 1.000 29.22301  ? 358 LEU A O    1 
ATOM   5488 C  CB   . LEU A 1 378 ? 9.55018   -32.92377 -18.49868 1.000 26.51934  ? 358 LEU A CB   1 
ATOM   5489 C  CG   . LEU A 1 378 ? 8.88139   -31.62138 -18.91181 1.000 27.33477  ? 358 LEU A CG   1 
ATOM   5490 C  CD1  . LEU A 1 378 ? 9.37569   -31.24394 -20.32098 1.000 26.70555  ? 358 LEU A CD1  1 
ATOM   5491 C  CD2  . LEU A 1 378 ? 7.36358   -31.70800 -18.90567 1.000 27.55676  ? 358 LEU A CD2  1 
ATOM   5492 H  H    . LEU A 1 378 ? 10.95074  -31.82119 -16.84166 1.000 29.02689  ? 358 LEU A H    1 
ATOM   5493 H  HA   . LEU A 1 378 ? 8.67414   -33.02878 -16.62684 1.000 32.86437  ? 358 LEU A HA   1 
ATOM   5494 H  HB2  . LEU A 1 378 ? 10.47029  -32.88545 -18.80337 1.000 31.84697  ? 358 LEU A HB2  1 
ATOM   5495 H  HB3  . LEU A 1 378 ? 9.08162   -33.64445 -18.94809 1.000 31.84697  ? 358 LEU A HB3  1 
ATOM   5496 H  HG   . LEU A 1 378 ? 9.11769   -30.93605 -18.26729 1.000 32.82549  ? 358 LEU A HG   1 
ATOM   5497 H  HD11 . LEU A 1 378 ? 8.90237   -30.45184 -20.62004 1.000 32.07042  ? 358 LEU A HD11 1 
ATOM   5498 H  HD12 . LEU A 1 378 ? 10.32848  -31.06579 -20.28424 1.000 32.07042  ? 358 LEU A HD12 1 
ATOM   5499 H  HD13 . LEU A 1 378 ? 9.20025   -31.98204 -20.92540 1.000 32.07042  ? 358 LEU A HD13 1 
ATOM   5500 H  HD21 . LEU A 1 378 ? 6.99733   -30.85228 -19.17862 1.000 33.09188  ? 358 LEU A HD21 1 
ATOM   5501 H  HD22 . LEU A 1 378 ? 7.08426   -32.40013 -19.52521 1.000 33.09188  ? 358 LEU A HD22 1 
ATOM   5502 H  HD23 . LEU A 1 378 ? 7.06331   -31.92556 -18.00934 1.000 33.09188  ? 358 LEU A HD23 1 
ATOM   5503 N  N    . ARG A 1 379 ? 11.13693  -35.06853 -16.79071 1.000 26.35398  ? 359 ARG A N    1 
ATOM   5504 C  CA   . ARG A 1 379 ? 11.53115  -36.46730 -16.74543 1.000 29.77208  ? 359 ARG A CA   1 
ATOM   5505 C  C    . ARG A 1 379 ? 11.60217  -36.99684 -15.31701 1.000 28.22672  ? 359 ARG A C    1 
ATOM   5506 O  O    . ARG A 1 379 ? 11.24775  -38.15566 -15.06989 1.000 29.69269  ? 359 ARG A O    1 
ATOM   5507 C  CB   . ARG A 1 379 ? 12.88379  -36.62045 -17.43941 1.000 31.96742  ? 359 ARG A CB   1 
ATOM   5508 C  CG   . ARG A 1 379 ? 13.56158  -37.96039 -17.22704 1.000 41.26329  ? 359 ARG A CG   1 
ATOM   5509 C  CD   . ARG A 1 379 ? 14.59494  -38.21411 -18.32574 1.000 55.00641  ? 359 ARG A CD   1 
ATOM   5510 N  NE   . ARG A 1 379 ? 15.52453  -37.09922 -18.50662 1.000 51.42111  ? 359 ARG A NE   1 
ATOM   5511 C  CZ   . ARG A 1 379 ? 16.52972  -36.82350 -17.68672 1.000 51.38337  ? 359 ARG A CZ   1 
ATOM   5512 N  NH1  . ARG A 1 379 ? 16.72392  -37.51367 -16.56925 1.000 51.07930  ? 359 ARG A NH1  1 
ATOM   5513 N  NH2  . ARG A 1 379 ? 17.38264  -35.85689 -18.01283 1.000 43.43260  ? 359 ARG A NH2  1 
ATOM   5514 H  H    . ARG A 1 379 ? 11.79989  -34.52333 -16.84404 1.000 31.64854  ? 359 ARG A H    1 
ATOM   5515 H  HA   . ARG A 1 379 ? 10.87182  -37.00085 -17.21607 1.000 35.75026  ? 359 ARG A HA   1 
ATOM   5516 H  HB2  . ARG A 1 379 ? 12.75410  -36.50758 -18.39405 1.000 38.38467  ? 359 ARG A HB2  1 
ATOM   5517 H  HB3  . ARG A 1 379 ? 13.48160  -35.93488 -17.10247 1.000 38.38467  ? 359 ARG A HB3  1 
ATOM   5518 H  HG2  . ARG A 1 379 ? 14.01445  -37.96392 -16.36925 1.000 49.53971  ? 359 ARG A HG2  1 
ATOM   5519 H  HG3  . ARG A 1 379 ? 12.89924  -38.66848 -17.25543 1.000 49.53971  ? 359 ARG A HG3  1 
ATOM   5520 H  HD2  . ARG A 1 379 ? 15.11355  -39.00068 -18.09499 1.000 66.03145  ? 359 ARG A HD2  1 
ATOM   5521 H  HD3  . ARG A 1 379 ? 14.13251  -38.35651 -19.16644 1.000 66.03145  ? 359 ARG A HD3  1 
ATOM   5522 H  HE   . ARG A 1 379 ? 15.41176  -36.58897 -19.18965 1.000 61.72910  ? 359 ARG A HE   1 
ATOM   5523 H  HH11 . ARG A 1 379 ? 16.19129  -38.15655 -16.36284 1.000 61.31893  ? 359 ARG A HH11 1 
ATOM   5524 H  HH12 . ARG A 1 379 ? 17.38235  -37.31783 -16.05184 1.000 61.31893  ? 359 ARG A HH12 1 
ATOM   5525 H  HH21 . ARG A 1 379 ? 17.27808  -35.42063 -18.74655 1.000 52.14288  ? 359 ARG A HH21 1 
ATOM   5526 H  HH22 . ARG A 1 379 ? 18.03883  -35.66798 -17.49002 1.000 52.14288  ? 359 ARG A HH22 1 
ATOM   5527 N  N    . ARG A 1 380 ? 12.09390  -36.18297 -14.37468 1.000 28.50947  ? 360 ARG A N    1 
ATOM   5528 C  CA   . ARG A 1 380 ? 12.37992  -36.66485 -13.03204 1.000 29.43217  ? 360 ARG A CA   1 
ATOM   5529 C  C    . ARG A 1 380 ? 11.23870  -36.41156 -12.06230 1.000 29.15953  ? 360 ARG A C    1 
ATOM   5530 O  O    . ARG A 1 380 ? 11.11163  -37.14725 -11.07610 1.000 30.55212  ? 360 ARG A O    1 
ATOM   5531 C  CB   . ARG A 1 380 ? 13.67689  -36.04607 -12.49119 1.000 31.35450  ? 360 ARG A CB   1 
ATOM   5532 C  CG   . ARG A 1 380 ? 14.91232  -36.45634 -13.31518 1.000 32.79830  ? 360 ARG A CG   1 
ATOM   5533 C  CD   . ARG A 1 380 ? 16.20576  -36.05907 -12.67168 1.000 32.60639  ? 360 ARG A CD   1 
ATOM   5534 N  NE   . ARG A 1 380 ? 16.35173  -36.62966 -11.33612 1.000 30.81443  ? 360 ARG A NE   1 
ATOM   5535 C  CZ   . ARG A 1 380 ? 17.28524  -36.24927 -10.47930 1.000 31.89779  ? 360 ARG A CZ   1 
ATOM   5536 N  NH1  . ARG A 1 380 ? 18.20290  -35.35152 -10.81386 1.000 30.82354  ? 360 ARG A NH1  1 
ATOM   5537 N  NH2  . ARG A 1 380 ? 17.25746  -36.72130 -9.23908  1.000 33.31648  ? 360 ARG A NH2  1 
ATOM   5538 H  H    . ARG A 1 380 ? 12.26791  -35.34940 -14.49499 1.000 34.23513  ? 360 ARG A H    1 
ATOM   5539 H  HA   . ARG A 1 380 ? 12.52906  -37.62267 -13.06716 1.000 35.34237  ? 360 ARG A HA   1 
ATOM   5540 H  HB2  . ARG A 1 380 ? 13.60267  -35.07933 -12.51963 1.000 37.64916  ? 360 ARG A HB2  1 
ATOM   5541 H  HB3  . ARG A 1 380 ? 13.81197  -36.34169 -11.57727 1.000 37.64916  ? 360 ARG A HB3  1 
ATOM   5542 H  HG2  . ARG A 1 380 ? 14.91529  -37.42065 -13.42007 1.000 39.38172  ? 360 ARG A HG2  1 
ATOM   5543 H  HG3  . ARG A 1 380 ? 14.86789  -36.02821 -14.18445 1.000 39.38172  ? 360 ARG A HG3  1 
ATOM   5544 H  HD2  . ARG A 1 380 ? 16.94336  -36.37362 -13.21749 1.000 39.15143  ? 360 ARG A HD2  1 
ATOM   5545 H  HD3  . ARG A 1 380 ? 16.23947  -35.09283 -12.59337 1.000 39.15143  ? 360 ARG A HD3  1 
ATOM   5546 H  HE   . ARG A 1 380 ? 15.80228  -37.24518 -11.09358 1.000 37.00108  ? 360 ARG A HE   1 
ATOM   5547 H  HH11 . ARG A 1 380 ? 18.19846  -35.00484 -11.60087 1.000 37.01201  ? 360 ARG A HH11 1 
ATOM   5548 H  HH12 . ARG A 1 380 ? 18.80222  -35.11623 -10.24372 1.000 37.01201  ? 360 ARG A HH12 1 
ATOM   5549 H  HH21 . ARG A 1 380 ? 16.63760  -37.26772 -9.00074  1.000 40.00354  ? 360 ARG A HH21 1 
ATOM   5550 H  HH22 . ARG A 1 380 ? 17.85931  -36.48072 -8.67384  1.000 40.00354  ? 360 ARG A HH22 1 
ATOM   5551 N  N    . LEU A 1 381 ? 10.39424  -35.43297 -12.35084 1.000 28.18796  ? 361 LEU A N    1 
ATOM   5552 C  CA   . LEU A 1 381 ? 9.20853   -35.10885 -11.55795 1.000 29.15706  ? 361 LEU A CA   1 
ATOM   5553 C  C    . LEU A 1 381 ? 7.97623   -35.26013 -12.44723 1.000 26.48231  ? 361 LEU A C    1 
ATOM   5554 O  O    . LEU A 1 381 ? 7.25085   -34.29770 -12.69102 1.000 26.67678  ? 361 LEU A O    1 
ATOM   5555 C  CB   . LEU A 1 381 ? 9.30492   -33.69946 -10.97610 1.000 28.56960  ? 361 LEU A CB   1 
ATOM   5556 C  CG   . LEU A 1 381 ? 10.63391  -33.28123 -10.33201 1.000 27.21973  ? 361 LEU A CG   1 
ATOM   5557 C  CD1  . LEU A 1 381 ? 10.62706  -31.79687 -9.92547  1.000 27.82639  ? 361 LEU A CD1  1 
ATOM   5558 C  CD2  . LEU A 1 381 ? 10.96848  -34.20274 -9.14655  1.000 27.89908  ? 361 LEU A CD2  1 
ATOM   5559 H  H    . LEU A 1 381 ? 10.48800  -34.91653 -13.03209 1.000 33.84931  ? 361 LEU A H    1 
ATOM   5560 H  HA   . LEU A 1 381 ? 9.13239   -35.72113 -10.80947 1.000 35.01223  ? 361 LEU A HA   1 
ATOM   5561 H  HB2  . LEU A 1 381 ? 9.13234   -33.07084 -11.69441 1.000 34.30728  ? 361 LEU A HB2  1 
ATOM   5562 H  HB3  . LEU A 1 381 ? 8.62351   -33.61547 -10.29088 1.000 34.30728  ? 361 LEU A HB3  1 
ATOM   5563 H  HG   . LEU A 1 381 ? 11.34304  -33.37790 -10.98675 1.000 32.68743  ? 361 LEU A HG   1 
ATOM   5564 H  HD11 . LEU A 1 381 ? 11.49703  -31.56413 -9.56507  1.000 33.41543  ? 361 LEU A HD11 1 
ATOM   5565 H  HD12 . LEU A 1 381 ? 10.43775  -31.25596 -10.70808 1.000 33.41543  ? 361 LEU A HD12 1 
ATOM   5566 H  HD13 . LEU A 1 381 ? 9.94219   -31.65677 -9.25299  1.000 33.41543  ? 361 LEU A HD13 1 
ATOM   5567 H  HD21 . LEU A 1 381 ? 11.81926  -33.93266 -8.76691  1.000 33.50266  ? 361 LEU A HD21 1 
ATOM   5568 H  HD22 . LEU A 1 381 ? 10.26892  -34.12526 -8.47908  1.000 33.50266  ? 361 LEU A HD22 1 
ATOM   5569 H  HD23 . LEU A 1 381 ? 11.02330  -35.11784 -9.46356  1.000 33.50266  ? 361 LEU A HD23 1 
ATOM   5570 N  N    . PRO A 1 382 ? 7.76106   -36.44213 -13.02650 1.000 27.94220  ? 362 PRO A N    1 
ATOM   5571 C  CA   . PRO A 1 382 ? 6.77149   -36.53967 -14.11287 1.000 29.76247  ? 362 PRO A CA   1 
ATOM   5572 C  C    . PRO A 1 382 ? 5.34561   -36.26522 -13.70839 1.000 32.78211  ? 362 PRO A C    1 
ATOM   5573 O  O    . PRO A 1 382 ? 4.54129   -35.97626 -14.59761 1.000 31.21628  ? 362 PRO A O    1 
ATOM   5574 C  CB   . PRO A 1 382 ? 6.92068   -37.98442 -14.60758 1.000 32.23760  ? 362 PRO A CB   1 
ATOM   5575 C  CG   . PRO A 1 382 ? 7.52575   -38.72043 -13.45300 1.000 31.45911  ? 362 PRO A CG   1 
ATOM   5576 C  CD   . PRO A 1 382 ? 8.47891   -37.71675 -12.84391 1.000 28.81327  ? 362 PRO A CD   1 
ATOM   5577 H  HA   . PRO A 1 382 ? 7.02420   -35.91758 -14.81290 1.000 35.73872  ? 362 PRO A HA   1 
ATOM   5578 H  HB2  . PRO A 1 382 ? 6.05079   -38.34827 -14.83519 1.000 38.70888  ? 362 PRO A HB2  1 
ATOM   5579 H  HB3  . PRO A 1 382 ? 7.50432   -38.01096 -15.38189 1.000 38.70888  ? 362 PRO A HB3  1 
ATOM   5580 H  HG2  . PRO A 1 382 ? 6.83634   -38.97792 -12.82109 1.000 37.77470  ? 362 PRO A HG2  1 
ATOM   5581 H  HG3  . PRO A 1 382 ? 7.99824   -39.50711 -13.76733 1.000 37.77470  ? 362 PRO A HG3  1 
ATOM   5582 H  HD2  . PRO A 1 382 ? 8.62527   -37.90217 -11.90311 1.000 34.59969  ? 362 PRO A HD2  1 
ATOM   5583 H  HD3  . PRO A 1 382 ? 9.32602   -37.70997 -13.31641 1.000 34.59969  ? 362 PRO A HD3  1 
ATOM   5584 N  N    . ASP A 1 383 ? 4.97566   -36.41321 -12.43103 1.000 29.93758  ? 363 ASP A N    1 
ATOM   5585 C  CA   . ASP A 1 383 ? 3.60414   -36.13025 -12.00488 1.000 28.35197  ? 363 ASP A CA   1 
ATOM   5586 C  C    . ASP A 1 383 ? 3.52379   -34.84336 -11.17750 1.000 31.94597  ? 363 ASP A C    1 
ATOM   5587 O  O    . ASP A 1 383 ? 2.60953   -34.67266 -10.35495 1.000 32.08081  ? 363 ASP A O    1 
ATOM   5588 C  CB   . ASP A 1 383 ? 3.01198   -37.31917 -11.25827 1.000 31.40411  ? 363 ASP A CB   1 
ATOM   5589 C  CG   . ASP A 1 383 ? 3.73368   -37.66669 -9.97214  1.000 33.86278  ? 363 ASP A CG   1 
ATOM   5590 O  OD1  . ASP A 1 383 ? 4.85188   -37.18756 -9.70846  1.000 33.25017  ? 363 ASP A OD1  1 
ATOM   5591 O  OD2  . ASP A 1 383 ? 3.16100   -38.50292 -9.24303  1.000 37.10366  ? 363 ASP A OD2  1 
ATOM   5592 H  H    . ASP A 1 383 ? 5.49873   -36.67421 -11.80026 1.000 35.94885  ? 363 ASP A H    1 
ATOM   5593 H  HA   . ASP A 1 383 ? 3.05354   -35.99507 -12.79194 1.000 34.04612  ? 363 ASP A HA   1 
ATOM   5594 H  HB2  . ASP A 1 383 ? 2.09060   -37.11659 -11.03264 1.000 37.70869  ? 363 ASP A HB2  1 
ATOM   5595 H  HB3  . ASP A 1 383 ? 3.04870   -38.09792 -11.83543 1.000 37.70869  ? 363 ASP A HB3  1 
ATOM   5596 N  N    . LEU A 1 384 ? 4.46109   -33.93529 -11.40800 1.000 27.38248  ? 364 LEU A N    1 
ATOM   5597 C  CA   . LEU A 1 384 ? 4.48317   -32.63381 -10.73888 1.000 28.10054  ? 364 LEU A CA   1 
ATOM   5598 C  C    . LEU A 1 384 ? 3.12871   -31.94270 -10.83201 1.000 29.65932  ? 364 LEU A C    1 
ATOM   5599 O  O    . LEU A 1 384 ? 2.49021   -31.93427 -11.88940 1.000 28.90744  ? 364 LEU A O    1 
ATOM   5600 C  CB   . LEU A 1 384 ? 5.57125   -31.74816 -11.35017 1.000 25.16230  ? 364 LEU A CB   1 
ATOM   5601 C  CG   . LEU A 1 384 ? 5.91061   -30.44536 -10.64736 1.000 24.27989  ? 364 LEU A CG   1 
ATOM   5602 C  CD1  . LEU A 1 384 ? 6.62941   -30.79911 -9.30690  1.000 24.55418  ? 364 LEU A CD1  1 
ATOM   5603 C  CD2  . LEU A 1 384 ? 6.79796   -29.61951 -11.57988 1.000 23.93276  ? 364 LEU A CD2  1 
ATOM   5604 H  H    . LEU A 1 384 ? 5.11221   -34.04589 -11.95882 1.000 32.88274  ? 364 LEU A H    1 
ATOM   5605 H  HA   . LEU A 1 384 ? 4.68774   -32.76789 -9.80022  1.000 33.74441  ? 364 LEU A HA   1 
ATOM   5606 H  HB2  . LEU A 1 384 ? 6.38960   -32.26789 -11.38315 1.000 30.21852  ? 364 LEU A HB2  1 
ATOM   5607 H  HB3  . LEU A 1 384 ? 5.29016   -31.51457 -12.24868 1.000 30.21852  ? 364 LEU A HB3  1 
ATOM   5608 H  HG   . LEU A 1 384 ? 5.12718   -29.91352 -10.43693 1.000 29.15963  ? 364 LEU A HG   1 
ATOM   5609 H  HD11 . LEU A 1 384 ? 7.00090   -29.98882 -8.92437  1.000 29.48878  ? 364 LEU A HD11 1 
ATOM   5610 H  HD12 . LEU A 1 384 ? 5.98431   -31.18789 -8.69567  1.000 29.48878  ? 364 LEU A HD12 1 
ATOM   5611 H  HD13 . LEU A 1 384 ? 7.33910   -31.43523 -9.48742  1.000 29.48878  ? 364 LEU A HD13 1 
ATOM   5612 H  HD21 . LEU A 1 384 ? 7.02444   -28.78395 -11.14232 1.000 28.74307  ? 364 LEU A HD21 1 
ATOM   5613 H  HD22 . LEU A 1 384 ? 7.60539   -30.12094 -11.77356 1.000 28.74307  ? 364 LEU A HD22 1 
ATOM   5614 H  HD23 . LEU A 1 384 ? 6.31372   -29.44203 -12.40141 1.000 28.74307  ? 364 LEU A HD23 1 
ATOM   5615 N  N    . ARG A 1 385 ? 2.67960   -31.37618 -9.70627  1.000 27.57260  ? 365 ARG A N    1 
ATOM   5616 C  CA   . ARG A 1 385 ? 1.48395   -30.53546 -9.72157  1.000 28.30163  ? 365 ARG A CA   1 
ATOM   5617 C  C    . ARG A 1 385 ? 1.58239   -29.41230 -8.68436  1.000 26.00874  ? 365 ARG A C    1 
ATOM   5618 O  O    . ARG A 1 385 ? 2.34005   -29.48910 -7.71315  1.000 25.80731  ? 365 ARG A O    1 
ATOM   5619 C  CB   . ARG A 1 385 ? 0.23650   -31.40211 -9.49924  1.000 37.47620  ? 365 ARG A CB   1 
ATOM   5620 C  CG   . ARG A 1 385 ? 0.16920   -32.07433 -8.16021  1.000 38.60253  ? 365 ARG A CG   1 
ATOM   5621 C  CD   . ARG A 1 385 ? -1.23487  -32.71311 -7.90892  1.000 43.83720  ? 365 ARG A CD   1 
ATOM   5622 N  NE   . ARG A 1 385 ? -1.28844  -33.31754 -6.58639  1.000 43.00718  ? 365 ARG A NE   1 
ATOM   5623 C  CZ   . ARG A 1 385 ? -0.76653  -34.49814 -6.29976  1.000 45.19750  ? 365 ARG A CZ   1 
ATOM   5624 N  NH1  . ARG A 1 385 ? -0.25793  -35.27838 -7.24347  1.000 59.18863  ? 365 ARG A NH1  1 
ATOM   5625 N  NH2  . ARG A 1 385 ? -0.72638  -34.90106 -5.04045  1.000 44.17682  ? 365 ARG A NH2  1 
ATOM   5626 H  H    . ARG A 1 385 ? 3.04657   -31.46401 -8.93347  1.000 33.11088  ? 365 ARG A H    1 
ATOM   5627 H  HA   . ARG A 1 385 ? 1.41701   -30.08511 -10.57808 1.000 33.98572  ? 365 ARG A HA   1 
ATOM   5628 H  HB2  . ARG A 1 385 ? -0.54870  -30.83874 -9.58278  1.000 44.99520  ? 365 ARG A HB2  1 
ATOM   5629 H  HB3  . ARG A 1 385 ? 0.21976   -32.09699 -10.17582 1.000 44.99520  ? 365 ARG A HB3  1 
ATOM   5630 H  HG2  . ARG A 1 385 ? 0.83566   -32.77798 -8.12023  1.000 46.34680  ? 365 ARG A HG2  1 
ATOM   5631 H  HG3  . ARG A 1 385 ? 0.33537   -31.42003 -7.46366  1.000 46.34680  ? 365 ARG A HG3  1 
ATOM   5632 H  HD2  . ARG A 1 385 ? -1.91866  -32.02731 -7.96379  1.000 52.62841  ? 365 ARG A HD2  1 
ATOM   5633 H  HD3  . ARG A 1 385 ? -1.40196  -33.40194 -8.57111  1.000 52.62841  ? 365 ARG A HD3  1 
ATOM   5634 H  HE   . ARG A 1 385 ? -1.68112  -32.88307 -5.95660  1.000 51.63238  ? 365 ARG A HE   1 
ATOM   5635 H  HH11 . ARG A 1 385 ? -0.26269  -35.02007 -8.06374  1.000 71.05012  ? 365 ARG A HH11 1 
ATOM   5636 H  HH12 . ARG A 1 385 ? 0.07672   -36.04275 -7.03529  1.000 71.05012  ? 365 ARG A HH12 1 
ATOM   5637 H  HH21 . ARG A 1 385 ? -1.03791  -34.39666 -4.41745  1.000 53.03594  ? 365 ARG A HH21 1 
ATOM   5638 H  HH22 . ARG A 1 385 ? -0.38874  -35.66741 -4.84474  1.000 53.03594  ? 365 ARG A HH22 1 
ATOM   5639 N  N    . LEU A 1 386 ? 0.78936   -28.36999 -8.90205  1.000 27.77470  ? 366 LEU A N    1 
ATOM   5640 C  CA   . LEU A 1 386 ? 0.70690   -27.26014 -7.96155  1.000 27.55154  ? 366 LEU A CA   1 
ATOM   5641 C  C    . LEU A 1 386 ? -0.01979  -27.70538 -6.69174  1.000 32.92036  ? 366 LEU A C    1 
ATOM   5642 O  O    . LEU A 1 386 ? -0.94629  -28.52160 -6.73204  1.000 35.23339  ? 366 LEU A O    1 
ATOM   5643 C  CB   . LEU A 1 386 ? -0.05243  -26.09311 -8.58832  1.000 30.43036  ? 366 LEU A CB   1 
ATOM   5644 C  CG   . LEU A 1 386 ? 0.59190   -25.35931 -9.73514  1.000 30.89001  ? 366 LEU A CG   1 
ATOM   5645 C  CD1  . LEU A 1 386 ? -0.45801  -24.50331 -10.44243 1.000 38.96941  ? 366 LEU A CD1  1 
ATOM   5646 C  CD2  . LEU A 1 386 ? 1.71762   -24.49729 -9.22536  1.000 29.55914  ? 366 LEU A CD2  1 
ATOM   5647 H  H    . LEU A 1 386 ? 0.28437   -28.27987 -9.59232  1.000 33.35340  ? 366 LEU A H    1 
ATOM   5648 H  HA   . LEU A 1 386 ? 1.60133   -26.96298 -7.73220  1.000 33.08561  ? 366 LEU A HA   1 
ATOM   5649 H  HB2  . LEU A 1 386 ? -0.89795  -26.43581 -8.91782  1.000 36.54019  ? 366 LEU A HB2  1 
ATOM   5650 H  HB3  . LEU A 1 386 ? -0.20938  -25.43667 -7.89165  1.000 36.54019  ? 366 LEU A HB3  1 
ATOM   5651 H  HG   . LEU A 1 386 ? 0.95949   -25.99183 -10.37209 1.000 37.09178  ? 366 LEU A HG   1 
ATOM   5652 H  HD11 . LEU A 1 386 ? -0.03363  -24.01766 -11.16696 1.000 46.78705  ? 366 LEU A HD11 1 
ATOM   5653 H  HD12 . LEU A 1 386 ? -1.15247  -25.08199 -10.79424 1.000 46.78705  ? 366 LEU A HD12 1 
ATOM   5654 H  HD13 . LEU A 1 386 ? -0.83885  -23.87960 -9.80458  1.000 46.78705  ? 366 LEU A HD13 1 
ATOM   5655 H  HD21 . LEU A 1 386 ? 2.08068   -23.98301 -9.96333  1.000 35.49474  ? 366 LEU A HD21 1 
ATOM   5656 H  HD22 . LEU A 1 386 ? 1.37368   -23.89955 -8.54323  1.000 35.49474  ? 366 LEU A HD22 1 
ATOM   5657 H  HD23 . LEU A 1 386 ? 2.40635   -25.06729 -8.84898  1.000 35.49474  ? 366 LEU A HD23 1 
ATOM   5658 N  N    . VAL A 1 387 ? 0.41237   -27.20018 -5.53980  1.000 27.98697  ? 367 VAL A N    1 
ATOM   5659 C  CA   . VAL A 1 387 ? -0.22060  -27.65017 -4.29300  1.000 30.76124  ? 367 VAL A CA   1 
ATOM   5660 C  C    . VAL A 1 387 ? -1.71023  -27.36003 -4.30674  1.000 41.85942  ? 367 VAL A C    1 
ATOM   5661 O  O    . VAL A 1 387 ? -2.52703  -28.20281 -3.90330  1.000 49.89574  ? 367 VAL A O    1 
ATOM   5662 C  CB   . VAL A 1 387 ? 0.48647   -27.02743 -3.07329  1.000 31.17591  ? 367 VAL A CB   1 
ATOM   5663 C  CG1  . VAL A 1 387 ? -0.42198  -27.02544 -1.85559  1.000 34.26053  ? 367 VAL A CG1  1 
ATOM   5664 C  CG2  . VAL A 1 387 ? 1.76934   -27.80588 -2.82686  1.000 29.58475  ? 367 VAL A CG2  1 
ATOM   5665 H  H    . VAL A 1 387 ? 1.04204   -26.62118 -5.45109  1.000 33.60813  ? 367 VAL A H    1 
ATOM   5666 H  HA   . VAL A 1 387 ? -0.11763  -28.61257 -4.22915  1.000 36.93725  ? 367 VAL A HA   1 
ATOM   5667 H  HB   . VAL A 1 387 ? 0.70561   -26.09775 -3.24231  1.000 37.43485  ? 367 VAL A HB   1 
ATOM   5668 H  HG11 . VAL A 1 387 ? 0.11056   -26.84763 -1.06458  1.000 41.13639  ? 367 VAL A HG11 1 
ATOM   5669 H  HG12 . VAL A 1 387 ? -1.09403  -26.33444 -1.96409  1.000 41.13639  ? 367 VAL A HG12 1 
ATOM   5670 H  HG13 . VAL A 1 387 ? -0.84899  -27.89300 -1.77873  1.000 41.13639  ? 367 VAL A HG13 1 
ATOM   5671 H  HG21 . VAL A 1 387 ? 2.28219   -27.35877 -2.13550  1.000 35.52547  ? 367 VAL A HG21 1 
ATOM   5672 H  HG22 . VAL A 1 387 ? 1.54329   -28.70506 -2.54176  1.000 35.52547  ? 367 VAL A HG22 1 
ATOM   5673 H  HG23 . VAL A 1 387 ? 2.28178   -27.83880 -3.64979  1.000 35.52547  ? 367 VAL A HG23 1 
ATOM   5674 N  N    . ALA A 1 388 ? -2.09088  -26.17864 -4.75001  1.000 46.27741  ? 368 ALA A N    1 
ATOM   5675 C  CA   . ALA A 1 388 ? -3.49491  -25.81431 -4.90005  1.000 55.80390  ? 368 ALA A CA   1 
ATOM   5676 C  C    . ALA A 1 388 ? -3.70226  -25.40386 -6.35295  1.000 62.50381  ? 368 ALA A C    1 
ATOM   5677 O  O    . ALA A 1 388 ? -3.25676  -24.32828 -6.76569  1.000 59.58490  ? 368 ALA A O    1 
ATOM   5678 C  CB   . ALA A 1 388 ? -3.87041  -24.69425 -3.93094  1.000 52.69972  ? 368 ALA A CB   1 
ATOM   5679 H  H    . ALA A 1 388 ? -1.54556  -25.55351 -4.97682  1.000 55.55665  ? 368 ALA A H    1 
ATOM   5680 H  HA   . ALA A 1 388 ? -4.06790  -26.57333 -4.70910  1.000 66.98844  ? 368 ALA A HA   1 
ATOM   5681 H  HB1  . ALA A 1 388 ? -4.75617  -24.36761 -4.15375  1.000 63.26343  ? 368 ALA A HB1  1 
ATOM   5682 H  HB2  . ALA A 1 388 ? -3.86480  -25.04426 -3.02631  1.000 63.26343  ? 368 ALA A HB2  1 
ATOM   5683 H  HB3  . ALA A 1 388 ? -3.22309  -23.97638 -4.01188  1.000 63.26343  ? 368 ALA A HB3  1 
ATOM   5684 N  N    . ASP A 1 389 ? -4.34643  -26.27737 -7.13249  1.000 62.67969  ? 369 ASP A N    1 
ATOM   5685 C  CA   . ASP A 1 389 ? -4.51189  -26.02656 -8.55920  1.000 64.11561  ? 369 ASP A CA   1 
ATOM   5686 C  C    . ASP A 1 389 ? -5.30948  -24.75839 -8.84014  1.000 75.31719  ? 369 ASP A C    1 
ATOM   5687 O  O    . ASP A 1 389 ? -5.25265  -24.24319 -9.96393  1.000 74.40447  ? 369 ASP A O    1 
ATOM   5688 C  CB   . ASP A 1 389 ? -5.19102  -27.22601 -9.22784  1.000 64.12390  ? 369 ASP A CB   1 
ATOM   5689 H  H    . ASP A 1 389 ? -4.69291  -27.01552 -6.85919  1.000 75.23939  ? 369 ASP A H    1 
ATOM   5690 H  HA   . ASP A 1 389 ? -3.63312  -25.91677 -8.95494  1.000 76.96249  ? 369 ASP A HA   1 
ATOM   5691 N  N    . ASP A 1 390 ? -6.05828  -24.24858 -7.85677  1.000 77.98260  ? 370 ASP A N    1 
ATOM   5692 C  CA   . ASP A 1 390 ? -6.78239  -22.98818 -7.99419  1.000 80.12841  ? 370 ASP A CA   1 
ATOM   5693 C  C    . ASP A 1 390 ? -6.15710  -21.88688 -7.13863  1.000 70.04667  ? 370 ASP A C    1 
ATOM   5694 O  O    . ASP A 1 390 ? -6.84001  -20.96935 -6.68282  1.000 69.49536  ? 370 ASP A O    1 
ATOM   5695 C  CB   . ASP A 1 390 ? -8.26172  -23.16593 -7.64850  1.000 76.71223  ? 370 ASP A CB   1 
ATOM   5696 C  CG   . ASP A 1 390 ? -8.48138  -24.01274 -6.41301  1.000 82.62700  ? 370 ASP A CG   1 
ATOM   5697 O  OD1  . ASP A 1 390 ? -7.49267  -24.32630 -5.71400  1.000 80.41392  ? 370 ASP A OD1  1 
ATOM   5698 O  OD2  . ASP A 1 390 ? -9.64840  -24.37318 -6.14294  1.000 87.33048  ? 370 ASP A OD2  1 
ATOM   5699 H  H    . ASP A 1 390 ? -6.16155  -24.62347 -7.08970  1.000 93.60288  ? 370 ASP A H    1 
ATOM   5700 H  HA   . ASP A 1 390 ? -6.73548  -22.70720 -8.92142  1.000 96.17785  ? 370 ASP A HA   1 
ATOM   5701 H  HB2  . ASP A 1 390 ? -8.65493  -22.29398 -7.48732  1.000 92.07844  ? 370 ASP A HB2  1 
ATOM   5702 H  HB3  . ASP A 1 390 ? -8.70942  -23.59948 -8.39181  1.000 92.07844  ? 370 ASP A HB3  1 
ATOM   5703 N  N    . SER A 1 391 ? -4.85561  -21.97308 -6.91220  1.000 72.24404  ? 371 SER A N    1 
ATOM   5704 C  CA   . SER A 1 391 ? -4.13253  -20.92383 -6.21701  1.000 68.36350  ? 371 SER A CA   1 
ATOM   5705 C  C    . SER A 1 391 ? -3.89359  -19.74542 -7.15438  1.000 57.55615  ? 371 SER A C    1 
ATOM   5706 O  O    . SER A 1 391 ? -3.79797  -19.90957 -8.37261  1.000 53.03649  ? 371 SER A O    1 
ATOM   5707 C  CB   . SER A 1 391 ? -2.80530  -21.47158 -5.68143  1.000 63.73548  ? 371 SER A CB   1 
ATOM   5708 O  OG   . SER A 1 391 ? -2.03419  -22.10916 -6.70046  1.000 56.64193  ? 371 SER A OG   1 
ATOM   5709 H  H    . SER A 1 391 ? -4.36382  -22.63595 -7.15375  1.000 86.71661  ? 371 SER A H    1 
ATOM   5710 H  HA   . SER A 1 391 ? -4.64554  -20.60091 -5.45975  1.000 82.05997  ? 371 SER A HA   1 
ATOM   5711 H  HB2  . SER A 1 391 ? -2.28986  -20.73488 -5.31742  1.000 76.50634  ? 371 SER A HB2  1 
ATOM   5712 H  HB3  . SER A 1 391 ? -2.99542  -22.11948 -4.98502  1.000 76.50634  ? 371 SER A HB3  1 
ATOM   5713 H  HG   . SER A 1 391 ? -2.43704  -22.79053 -6.98161  1.000 67.99408  ? 371 SER A HG   1 
ATOM   5714 N  N    . VAL A 1 392 ? -3.85725  -18.54449 -6.57783  1.000 52.73210  ? 372 VAL A N    1 
ATOM   5715 C  CA   . VAL A 1 392 ? -3.33379  -17.35114 -7.24379  1.000 49.49031  ? 372 VAL A CA   1 
ATOM   5716 C  C    . VAL A 1 392 ? -2.04006  -16.99255 -6.52501  1.000 43.94264  ? 372 VAL A C    1 
ATOM   5717 O  O    . VAL A 1 392 ? -2.04812  -16.54765 -5.37115  1.000 44.58878  ? 372 VAL A O    1 
ATOM   5718 C  CB   . VAL A 1 392 ? -4.33798  -16.19076 -7.23658  1.000 47.51198  ? 372 VAL A CB   1 
ATOM   5719 C  CG1  . VAL A 1 392 ? -5.65225  -16.64271 -7.86198  1.000 53.40964  ? 372 VAL A CG1  1 
ATOM   5720 C  CG2  . VAL A 1 392 ? -4.59452  -15.71372 -5.80126  1.000 47.19421  ? 372 VAL A CG2  1 
ATOM   5721 H  H    . VAL A 1 392 ? -4.13791  -18.39183 -5.77938  1.000 63.30229  ? 372 VAL A H    1 
ATOM   5722 H  HA   . VAL A 1 392 ? -3.13272  -17.54948 -8.17176  1.000 59.41213  ? 372 VAL A HA   1 
ATOM   5723 H  HB   . VAL A 1 392 ? -3.97214  -15.45371 -7.75021  1.000 57.03814  ? 372 VAL A HB   1 
ATOM   5724 H  HG11 . VAL A 1 392 ? -6.27219  -15.89669 -7.86786  1.000 64.11533  ? 372 VAL A HG11 1 
ATOM   5725 H  HG12 . VAL A 1 392 ? -5.48415  -16.94027 -8.76978  1.000 64.11533  ? 372 VAL A HG12 1 
ATOM   5726 H  HG13 . VAL A 1 392 ? -6.01741  -17.37211 -7.33707  1.000 64.11533  ? 372 VAL A HG13 1 
ATOM   5727 H  HG21 . VAL A 1 392 ? -5.41644  -15.19898 -5.78170  1.000 56.65681  ? 372 VAL A HG21 1 
ATOM   5728 H  HG22 . VAL A 1 392 ? -4.67458  -16.48693 -5.22105  1.000 56.65681  ? 372 VAL A HG22 1 
ATOM   5729 H  HG23 . VAL A 1 392 ? -3.85096  -15.16067 -5.51464  1.000 56.65681  ? 372 VAL A HG23 1 
ATOM   5730 N  N    . LEU A 1 393 ? -0.99536  -17.19839 -7.14198  1.000 38.49576  ? 373 LEU A N    1 
ATOM   5731 C  CA   . LEU A 1 393 ? 0.25100   -17.03052 -6.40484  1.000 34.18579  ? 373 LEU A CA   1 
ATOM   5732 C  C    . LEU A 1 393 ? 0.76960   -15.59947 -6.49808  1.000 28.83994  ? 373 LEU A C    1 
ATOM   5733 O  O    . LEU A 1 393 ? 0.53799   -14.93811 -7.48899  1.000 30.58272  ? 373 LEU A O    1 
ATOM   5734 C  CB   . LEU A 1 393 ? 1.28263   -17.99778 -6.94965  1.000 29.08862  ? 373 LEU A CB   1 
ATOM   5735 C  CG   . LEU A 1 393 ? 0.88761   -19.47579 -6.77581  1.000 31.80839  ? 373 LEU A CG   1 
ATOM   5736 C  CD1  . LEU A 1 393 ? 1.67770   -20.27281 -7.81553  1.000 32.09990  ? 373 LEU A CD1  1 
ATOM   5737 C  CD2  . LEU A 1 393 ? 1.13976   -19.92704 -5.35706  1.000 33.12168  ? 373 LEU A CD2  1 
ATOM   5738 H  H    . LEU A 1 393 ? -0.92887  -17.43201 -7.96696  1.000 46.21868  ? 373 LEU A H    1 
ATOM   5739 H  HA   . LEU A 1 393 ? 0.10947   -17.21523 -5.46317  1.000 41.04671  ? 373 LEU A HA   1 
ATOM   5740 H  HB2  . LEU A 1 393 ? 1.39857   -17.82962 -7.89790  1.000 34.93011  ? 373 LEU A HB2  1 
ATOM   5741 H  HB3  . LEU A 1 393 ? 2.12097   -17.85624 -6.48268  1.000 34.93011  ? 373 LEU A HB3  1 
ATOM   5742 H  HG   . LEU A 1 393 ? -0.05936  -19.62635 -6.92240  1.000 38.19383  ? 373 LEU A HG   1 
ATOM   5743 H  HD11 . LEU A 1 393 ? 1.49335   -21.21761 -7.69605  1.000 38.54364  ? 373 LEU A HD11 1 
ATOM   5744 H  HD12 . LEU A 1 393 ? 1.40454   -19.99214 -8.70295  1.000 38.54364  ? 373 LEU A HD12 1 
ATOM   5745 H  HD13 . LEU A 1 393 ? 2.62450   -20.10226 -7.69147  1.000 38.54364  ? 373 LEU A HD13 1 
ATOM   5746 H  HD21 . LEU A 1 393 ? 0.95242   -20.87638 -5.28960  1.000 39.76977  ? 373 LEU A HD21 1 
ATOM   5747 H  HD22 . LEU A 1 393 ? 2.06755   -19.75612 -5.13148  1.000 39.76977  ? 373 LEU A HD22 1 
ATOM   5748 H  HD23 . LEU A 1 393 ? 0.55751   -19.43174 -4.75993  1.000 39.76977  ? 373 LEU A HD23 1 
ATOM   5749 N  N    . PRO A 1 394 ? 1.47477   -15.09155 -5.47497  1.000 28.19040  ? 374 PRO A N    1 
ATOM   5750 C  CA   . PRO A 1 394 ? 1.86058   -13.67748 -5.50053  1.000 27.13516  ? 374 PRO A CA   1 
ATOM   5751 C  C    . PRO A 1 394 ? 3.06525   -13.41565 -6.39448  1.000 24.34139  ? 374 PRO A C    1 
ATOM   5752 O  O    . PRO A 1 394 ? 4.00591   -14.21414 -6.50487  1.000 24.23374  ? 374 PRO A O    1 
ATOM   5753 C  CB   . PRO A 1 394 ? 2.18836   -13.35616 -4.04042  1.000 32.09872  ? 374 PRO A CB   1 
ATOM   5754 C  CG   . PRO A 1 394 ? 2.58418   -14.64320 -3.47141  1.000 34.59551  ? 374 PRO A CG   1 
ATOM   5755 C  CD   . PRO A 1 394 ? 1.68609   -15.66456 -4.13513  1.000 34.97246  ? 374 PRO A CD   1 
ATOM   5756 H  HA   . PRO A 1 394 ? 1.11081   -13.13908 -5.79864  1.000 32.58595  ? 374 PRO A HA   1 
ATOM   5757 H  HB2  . PRO A 1 394 ? 2.91473   -12.71489 -3.99494  1.000 38.54223  ? 374 PRO A HB2  1 
ATOM   5758 H  HB3  . PRO A 1 394 ? 1.40428   -13.00161 -3.59276  1.000 38.54223  ? 374 PRO A HB3  1 
ATOM   5759 H  HG2  . PRO A 1 394 ? 3.51649   -14.81986 -3.67262  1.000 41.53837  ? 374 PRO A HG2  1 
ATOM   5760 H  HG3  . PRO A 1 394 ? 2.44783   -14.63499 -2.51108  1.000 41.53837  ? 374 PRO A HG3  1 
ATOM   5761 H  HD2  . PRO A 1 394 ? 2.12493   -16.52774 -4.19205  1.000 41.99071  ? 374 PRO A HD2  1 
ATOM   5762 H  HD3  . PRO A 1 394 ? 0.84601   -15.75032 -3.65785  1.000 41.99071  ? 374 PRO A HD3  1 
ATOM   5763 N  N    . LEU A 1 395 ? 3.00268   -12.25818 -7.05072  1.000 24.31824  ? 375 LEU A N    1 
ATOM   5764 C  CA   . LEU A 1 395 ? 4.07869   -11.75600 -7.88086  1.000 20.93788  ? 375 LEU A CA   1 
ATOM   5765 C  C    . LEU A 1 395 ? 4.84714   -10.68433 -7.13547  1.000 23.51282  ? 375 LEU A C    1 
ATOM   5766 O  O    . LEU A 1 395 ? 4.27993   -9.96012  -6.31354  1.000 25.21497  ? 375 LEU A O    1 
ATOM   5767 C  CB   . LEU A 1 395 ? 3.51063   -11.16088 -9.17630  1.000 21.37760  ? 375 LEU A CB   1 
ATOM   5768 C  CG   . LEU A 1 395 ? 2.76338   -12.11665 -10.10455 1.000 25.63173  ? 375 LEU A CG   1 
ATOM   5769 C  CD1  . LEU A 1 395 ? 1.94171   -11.33159 -11.12756 1.000 23.92454  ? 375 LEU A CD1  1 
ATOM   5770 C  CD2  . LEU A 1 395 ? 3.72129   -13.06338 -10.81282 1.000 24.78299  ? 375 LEU A CD2  1 
ATOM   5771 H  H    . LEU A 1 395 ? 2.32185   -11.73334 -7.02568  1.000 29.20564  ? 375 LEU A H    1 
ATOM   5772 H  HA   . LEU A 1 395 ? 4.68759   -12.47705 -8.10497  1.000 25.14922  ? 375 LEU A HA   1 
ATOM   5773 H  HB2  . LEU A 1 395 ? 2.88910   -10.45651 -8.93450  1.000 25.67688  ? 375 LEU A HB2  1 
ATOM   5774 H  HB3  . LEU A 1 395 ? 4.24938   -10.79132 -9.68481  1.000 25.67688  ? 375 LEU A HB3  1 
ATOM   5775 H  HG   . LEU A 1 395 ? 2.16011   -12.65512 -9.56881  1.000 30.78184  ? 375 LEU A HG   1 
ATOM   5776 H  HD11 . LEU A 1 395 ? 1.52452   -11.95480 -11.74275 1.000 28.73321  ? 375 LEU A HD11 1 
ATOM   5777 H  HD12 . LEU A 1 395 ? 1.26111   -10.82134 -10.66136 1.000 28.73321  ? 375 LEU A HD12 1 
ATOM   5778 H  HD13 . LEU A 1 395 ? 2.53038   -10.73220 -11.61242 1.000 28.73321  ? 375 LEU A HD13 1 
ATOM   5779 H  HD21 . LEU A 1 395 ? 3.21442   -13.64101 -11.40470 1.000 29.76336  ? 375 LEU A HD21 1 
ATOM   5780 H  HD22 . LEU A 1 395 ? 4.35899   -12.54229 -11.32536 1.000 29.76336  ? 375 LEU A HD22 1 
ATOM   5781 H  HD23 . LEU A 1 395 ? 4.18684   -13.59627 -10.14935 1.000 29.76336  ? 375 LEU A HD23 1 
ATOM   5782 N  N    . ARG A 1 396 ? 6.12727   -10.58848 -7.42586  1.000 22.43577  ? 376 ARG A N    1 
ATOM   5783 C  CA   . ARG A 1 396 ? 6.98244   -9.59166  -6.75395  1.000 24.25506  ? 376 ARG A CA   1 
ATOM   5784 C  C    . ARG A 1 396 ? 6.62256   -8.17330  -7.18069  1.000 23.73246  ? 376 ARG A C    1 
ATOM   5785 O  O    . ARG A 1 396 ? 6.67245   -7.85653  -8.37628  1.000 23.34915  ? 376 ARG A O    1 
ATOM   5786 C  CB   . ARG A 1 396 ? 8.42958   -9.88282  -7.07114  1.000 27.67260  ? 376 ARG A CB   1 
ATOM   5787 C  CG   . ARG A 1 396 ? 9.39799   -8.84941  -6.52468  1.000 42.75439  ? 376 ARG A CG   1 
ATOM   5788 C  CD   . ARG A 1 396 ? 10.76315  -9.47141  -6.17402  1.000 57.95649  ? 376 ARG A CD   1 
ATOM   5789 N  NE   . ARG A 1 396 ? 11.39222  -8.79342  -5.04122  1.000 67.47633  ? 376 ARG A NE   1 
ATOM   5790 C  CZ   . ARG A 1 396 ? 12.60000  -9.07662  -4.56800  1.000 73.68889  ? 376 ARG A CZ   1 
ATOM   5791 N  NH1  . ARG A 1 396 ? 13.35687  -10.01284 -5.11801  1.000 68.76713  ? 376 ARG A NH1  1 
ATOM   5792 N  NH2  . ARG A 1 396 ? 13.06305  -8.39792  -3.52119  1.000 68.89889  ? 376 ARG A NH2  1 
ATOM   5793 H  H    . ARG A 1 396 ? 6.53661   -11.07846 -8.00202  1.000 26.94668  ? 376 ARG A H    1 
ATOM   5794 H  HA   . ARG A 1 396 ? 6.84283   -9.64904  -5.79577  1.000 29.12983  ? 376 ARG A HA   1 
ATOM   5795 H  HB2  . ARG A 1 396 ? 8.66583   -10.74165 -6.68708  1.000 33.23088  ? 376 ARG A HB2  1 
ATOM   5796 H  HB3  . ARG A 1 396 ? 8.53795   -9.90920  -8.03470  1.000 33.23088  ? 376 ARG A HB3  1 
ATOM   5797 H  HG2  . ARG A 1 396 ? 9.54108   -8.16049  -7.19238  1.000 51.32903  ? 376 ARG A HG2  1 
ATOM   5798 H  HG3  . ARG A 1 396 ? 9.02690   -8.45805  -5.71844  1.000 51.32903  ? 376 ARG A HG3  1 
ATOM   5799 H  HD2  . ARG A 1 396 ? 10.63913  -10.40438 -5.93931  1.000 69.57155  ? 376 ARG A HD2  1 
ATOM   5800 H  HD3  . ARG A 1 396 ? 11.35468  -9.39762  -6.93923  1.000 69.57155  ? 376 ARG A HD3  1 
ATOM   5801 H  HE   . ARG A 1 396 ? 10.94834  -8.16678  -4.65407  1.000 80.99536  ? 376 ARG A HE   1 
ATOM   5802 H  HH11 . ARG A 1 396 ? 13.06920  -10.45383 -5.79800  1.000 82.54431  ? 376 ARG A HH11 1 
ATOM   5803 H  HH12 . ARG A 1 396 ? 14.13631  -10.18017 -4.79540  1.000 82.54431  ? 376 ARG A HH12 1 
ATOM   5804 H  HH21 . ARG A 1 396 ? 12.58137  -7.78416  -3.15942  1.000 82.70243  ? 376 ARG A HH21 1 
ATOM   5805 H  HH22 . ARG A 1 396 ? 13.84399  -8.57306  -3.20645  1.000 82.70243  ? 376 ARG A HH22 1 
ATOM   5806 N  N    . PRO A 1 397 ? 6.28832   -7.27914  -6.25075  1.000 22.29397  ? 377 PRO A N    1 
ATOM   5807 C  CA   . PRO A 1 397 ? 6.13709   -5.85893  -6.63213  1.000 22.43714  ? 377 PRO A CA   1 
ATOM   5808 C  C    . PRO A 1 397 ? 7.49062   -5.26937  -7.01450  1.000 26.35849  ? 377 PRO A C    1 
ATOM   5809 O  O    . PRO A 1 397 ? 8.42911   -5.24018  -6.22130  1.000 30.31607  ? 377 PRO A O    1 
ATOM   5810 C  CB   . PRO A 1 397 ? 5.52759   -5.20248  -5.38831  1.000 27.43229  ? 377 PRO A CB   1 
ATOM   5811 C  CG   . PRO A 1 397 ? 5.68713   -6.17228  -4.30017  1.000 38.85979  ? 377 PRO A CG   1 
ATOM   5812 C  CD   . PRO A 1 397 ? 5.83950   -7.54447  -4.87456  1.000 27.19592  ? 377 PRO A CD   1 
ATOM   5813 H  HA   . PRO A 1 397 ? 5.51624   -5.75531  -7.37018  1.000 26.94833  ? 377 PRO A HA   1 
ATOM   5814 H  HB2  . PRO A 1 397 ? 6.00185   -4.38038  -5.18798  1.000 32.94250  ? 377 PRO A HB2  1 
ATOM   5815 H  HB3  . PRO A 1 397 ? 4.58915   -5.01419  -5.54573  1.000 32.94250  ? 377 PRO A HB3  1 
ATOM   5816 H  HG2  . PRO A 1 397 ? 6.47696   -5.93933  -3.78753  1.000 46.65551  ? 377 PRO A HG2  1 
ATOM   5817 H  HG3  . PRO A 1 397 ? 4.90112   -6.13720  -3.73284  1.000 46.65551  ? 377 PRO A HG3  1 
ATOM   5818 H  HD2  . PRO A 1 397 ? 6.50499   -8.05290  -4.38514  1.000 32.65887  ? 377 PRO A HD2  1 
ATOM   5819 H  HD3  . PRO A 1 397 ? 4.99252   -8.01725  -4.87154  1.000 32.65887  ? 377 PRO A HD3  1 
ATOM   5820 N  N    . ALA A 1 398 ? 7.60841   -4.89445  -8.27590  1.000 20.85715  ? 378 ALA A N    1 
ATOM   5821 C  CA   . ALA A 1 398 ? 8.82119   -4.31552  -8.83541  1.000 20.21080  ? 378 ALA A CA   1 
ATOM   5822 C  C    . ALA A 1 398 ? 8.43688   -3.70537  -10.16692 1.000 21.55064  ? 378 ALA A C    1 
ATOM   5823 O  O    . ALA A 1 398 ? 7.65488   -4.31276  -10.89331 1.000 20.81810  ? 378 ALA A O    1 
ATOM   5824 C  CB   . ALA A 1 398 ? 9.90017   -5.37888  -9.04194  1.000 25.17075  ? 378 ALA A CB   1 
ATOM   5825 H  H    . ALA A 1 398 ? 6.97578   -4.96676  -8.85396  1.000 25.05234  ? 378 ALA A H    1 
ATOM   5826 H  HA   . ALA A 1 398 ? 9.18223   -3.63481  -8.24618  1.000 24.27672  ? 378 ALA A HA   1 
ATOM   5827 H  HB1  . ALA A 1 398 ? 10.60465  -5.01021  -9.59754  1.000 30.22866  ? 378 ALA A HB1  1 
ATOM   5828 H  HB2  . ALA A 1 398 ? 10.26001  -5.63553  -8.17848  1.000 30.22866  ? 378 ALA A HB2  1 
ATOM   5829 H  HB3  . ALA A 1 398 ? 9.50445   -6.14982  -9.47777  1.000 30.22866  ? 378 ALA A HB3  1 
ATOM   5830 N  N    . ASN A 1 399 ? 9.01009   -2.54445  -10.52059 1.000 21.66766  ? 379 ASN A N    1 
ATOM   5831 C  CA   . ASN A 1 399 ? 8.62748   -1.89354  -11.79176 1.000 21.13271  ? 379 ASN A CA   1 
ATOM   5832 C  C    . ASN A 1 399 ? 9.52166   -2.26186  -12.97860 1.000 19.87387  ? 379 ASN A C    1 
ATOM   5833 O  O    . ASN A 1 399 ? 9.34761   -1.69854  -14.07327 1.000 20.82104  ? 379 ASN A O    1 
ATOM   5834 C  CB   . ASN A 1 399 ? 8.55873   -0.36395  -11.63181 1.000 22.67279  ? 379 ASN A CB   1 
ATOM   5835 C  CG   . ASN A 1 399 ? 9.94137   0.30975   -11.58335 1.000 21.72445  ? 379 ASN A CG   1 
ATOM   5836 O  OD1  . ASN A 1 399 ? 10.97547  -0.30407  -11.87907 1.000 21.43109  ? 379 ASN A OD1  1 
ATOM   5837 N  ND2  . ASN A 1 399 ? 9.95436   1.59451   -11.22194 1.000 24.59562  ? 379 ASN A ND2  1 
ATOM   5838 H  H    . ASN A 1 399 ? 9.60305   -2.12659  -10.05864 1.000 26.02496  ? 379 ASN A H    1 
ATOM   5839 H  HA   . ASN A 1 399 ? 7.73381   -2.20226  -12.00844 1.000 25.38301  ? 379 ASN A HA   1 
ATOM   5840 H  HB2  . ASN A 1 399 ? 8.07324   0.00834   -12.38454 1.000 27.23112  ? 379 ASN A HB2  1 
ATOM   5841 H  HB3  . ASN A 1 399 ? 8.09783   -0.15582  -10.80408 1.000 27.23112  ? 379 ASN A HB3  1 
ATOM   5842 H  HD21 . ASN A 1 399 ? 10.69970  2.02128   -11.17785 1.000 29.53851  ? 379 ASN A HD21 1 
ATOM   5843 H  HD22 . ASN A 1 399 ? 9.21740   1.99557   -11.03315 1.000 29.53851  ? 379 ASN A HD22 1 
ATOM   5844 N  N    . PHE A 1 400 ? 10.45407  -3.20551  -12.81220 1.000 20.43922  ? 380 PHE A N    1 
ATOM   5845 C  CA   . PHE A 1 400 ? 11.47635  -3.46421  -13.81033 1.000 18.31292  ? 380 PHE A CA   1 
ATOM   5846 C  C    . PHE A 1 400 ? 11.47953  -4.94259  -14.15874 1.000 20.09769  ? 380 PHE A C    1 
ATOM   5847 O  O    . PHE A 1 400 ? 11.07736  -5.31154  -15.26375 1.000 19.52285  ? 380 PHE A O    1 
ATOM   5848 C  CB   . PHE A 1 400 ? 12.82936  -3.03093  -13.30844 1.000 20.34033  ? 380 PHE A CB   1 
ATOM   5849 C  CG   . PHE A 1 400 ? 13.94779  -3.16192  -14.30474 1.000 19.50515  ? 380 PHE A CG   1 
ATOM   5850 C  CD1  . PHE A 1 400 ? 13.75379  -3.00295  -15.68955 1.000 19.13063  ? 380 PHE A CD1  1 
ATOM   5851 C  CD2  . PHE A 1 400 ? 15.24074  -3.42993  -13.83998 1.000 21.37213  ? 380 PHE A CD2  1 
ATOM   5852 C  CE1  . PHE A 1 400 ? 14.82841  -3.07605  -16.58160 1.000 21.57035  ? 380 PHE A CE1  1 
ATOM   5853 C  CE2  . PHE A 1 400 ? 16.30613  -3.50456  -14.72517 1.000 22.42012  ? 380 PHE A CE2  1 
ATOM   5854 C  CZ   . PHE A 1 400 ? 16.10723  -3.32049  -16.07790 1.000 23.70929  ? 380 PHE A CZ   1 
ATOM   5855 H  H    . PHE A 1 400 ? 10.51070  -3.71162  -12.11921 1.000 24.55082  ? 380 PHE A H    1 
ATOM   5856 H  HA   . PHE A 1 400 ? 11.29070  -2.95393  -14.61411 1.000 21.99927  ? 380 PHE A HA   1 
ATOM   5857 H  HB2  . PHE A 1 400 ? 12.77694  -2.09715  -13.05113 1.000 24.43216  ? 380 PHE A HB2  1 
ATOM   5858 H  HB3  . PHE A 1 400 ? 13.06010  -3.57463  -12.53900 1.000 24.43216  ? 380 PHE A HB3  1 
ATOM   5859 H  HD1  . PHE A 1 400 ? 12.89734  -2.84681  -16.01668 1.000 22.98051  ? 380 PHE A HD1  1 
ATOM   5860 H  HD2  . PHE A 1 400 ? 15.38660  -3.55895  -12.93060 1.000 25.67032  ? 380 PHE A HD2  1 
ATOM   5861 H  HE1  . PHE A 1 400 ? 14.69337  -2.96372  -17.49486 1.000 25.90818  ? 380 PHE A HE1  1 
ATOM   5862 H  HE2  . PHE A 1 400 ? 17.16118  -3.68005  -14.40425 1.000 26.92791  ? 380 PHE A HE2  1 
ATOM   5863 H  HZ   . PHE A 1 400 ? 16.83179  -3.35962  -16.65961 1.000 28.47491  ? 380 PHE A HZ   1 
ATOM   5864 N  N    . VAL A 1 401 ? 11.86468  -5.78571  -13.19965 1.000 18.88678  ? 381 VAL A N    1 
ATOM   5865 C  CA   . VAL A 1 401 ? 11.90607  -7.24270  -13.37319 1.000 17.54859  ? 381 VAL A CA   1 
ATOM   5866 C  C    . VAL A 1 401 ? 11.01564  -7.87927  -12.32173 1.000 19.78094  ? 381 VAL A C    1 
ATOM   5867 O  O    . VAL A 1 401 ? 11.14232  -7.56945  -11.13347 1.000 20.84775  ? 381 VAL A O    1 
ATOM   5868 C  CB   . VAL A 1 401 ? 13.35064  -7.75009  -13.26523 1.000 18.12627  ? 381 VAL A CB   1 
ATOM   5869 C  CG1  . VAL A 1 401 ? 13.37549  -9.28672  -13.40392 1.000 22.91205  ? 381 VAL A CG1  1 
ATOM   5870 C  CG2  . VAL A 1 401 ? 14.23175  -7.13858  -14.32702 1.000 20.95924  ? 381 VAL A CG2  1 
ATOM   5871 H  H    . VAL A 1 401 ? 12.11403  -5.53168  -12.41678 1.000 22.68790  ? 381 VAL A H    1 
ATOM   5872 H  HA   . VAL A 1 401 ? 11.54960  -7.48850  -14.24118 1.000 21.08207  ? 381 VAL A HA   1 
ATOM   5873 H  HB   . VAL A 1 401 ? 13.69953  -7.49137  -12.39791 1.000 21.77529  ? 381 VAL A HB   1 
ATOM   5874 H  HG11 . VAL A 1 401 ? 14.29716  -9.58390  -13.45975 1.000 27.51822  ? 381 VAL A HG11 1 
ATOM   5875 H  HG12 . VAL A 1 401 ? 12.94731  -9.68081  -12.62787 1.000 27.51822  ? 381 VAL A HG12 1 
ATOM   5876 H  HG13 . VAL A 1 401 ? 12.89726  -9.53889  -14.20928 1.000 27.51822  ? 381 VAL A HG13 1 
ATOM   5877 H  HG21 . VAL A 1 401 ? 15.13290  -7.48317  -14.22654 1.000 25.17485  ? 381 VAL A HG21 1 
ATOM   5878 H  HG22 . VAL A 1 401 ? 13.88304  -7.37421  -15.20096 1.000 25.17485  ? 381 VAL A HG22 1 
ATOM   5879 H  HG23 . VAL A 1 401 ? 14.23243  -6.17450  -14.22008 1.000 25.17485  ? 381 VAL A HG23 1 
ATOM   5880 N  N    . SER A 1 402 ? 10.15664  -8.82015  -12.74028 1.000 18.57667  ? 382 SER A N    1 
ATOM   5881 C  CA   . SER A 1 402 ? 9.23776   -9.41991  -11.78151 1.000 19.17942  ? 382 SER A CA   1 
ATOM   5882 C  C    . SER A 1 402 ? 8.80276   -10.80657 -12.22209 1.000 19.25955  ? 382 SER A C    1 
ATOM   5883 O  O    . SER A 1 402 ? 8.74447   -11.12265 -13.42432 1.000 19.31823  ? 382 SER A O    1 
ATOM   5884 C  CB   . SER A 1 402 ? 7.99611   -8.53403  -11.58974 1.000 18.77619  ? 382 SER A CB   1 
ATOM   5885 O  OG   . SER A 1 402 ? 7.05863   -9.10169  -10.66990 1.000 21.91122  ? 382 SER A OG   1 
ATOM   5886 H  H    . SER A 1 402 ? 10.09406  -9.11299  -13.54647 1.000 22.31577  ? 382 SER A H    1 
ATOM   5887 H  HA   . SER A 1 402 ? 9.71175   -9.52531  -10.94180 1.000 23.03907  ? 382 SER A HA   1 
ATOM   5888 H  HB2  . SER A 1 402 ? 8.28076   -7.67162  -11.24897 1.000 22.55519  ? 382 SER A HB2  1 
ATOM   5889 H  HB3  . SER A 1 402 ? 7.55900   -8.42355  -12.44860 1.000 22.55519  ? 382 SER A HB3  1 
ATOM   5890 H  HG   . SER A 1 402 ? 6.57373   -8.49785  -10.34456 1.000 26.31722  ? 382 SER A HG   1 
ATOM   5891 N  N    . GLY A 1 403 ? 8.46342   -11.59548 -11.20795 1.000 18.62812  ? 383 GLY A N    1 
ATOM   5892 C  CA   . GLY A 1 403 ? 7.84210   -12.88961 -11.38511 1.000 20.08087  ? 383 GLY A CA   1 
ATOM   5893 C  C    . GLY A 1 403 ? 7.36397   -13.44478 -10.05207 1.000 19.75911  ? 383 GLY A C    1 
ATOM   5894 O  O    . GLY A 1 403 ? 7.18332   -12.72477 -9.06329  1.000 19.37973  ? 383 GLY A O    1 
ATOM   5895 H  H    . GLY A 1 403 ? 8.58846   -11.39349 -10.38142 1.000 22.37750  ? 383 GLY A H    1 
ATOM   5896 H  HA2  . GLY A 1 403 ? 7.08094   -12.80885 -11.98094 1.000 24.12081  ? 383 GLY A HA2  1 
ATOM   5897 H  HA3  . GLY A 1 403 ? 8.48065   -13.50963 -11.77076 1.000 24.12081  ? 383 GLY A HA3  1 
ATOM   5898 N  N    . LEU A 1 404 ? 7.12483   -14.75142 -10.02899 1.000 18.56319  ? 384 LEU A N    1 
ATOM   5899 C  CA   . LEU A 1 404 ? 6.50910   -15.36735 -8.85872  1.000 21.03719  ? 384 LEU A CA   1 
ATOM   5900 C  C    . LEU A 1 404 ? 7.41484   -15.33307 -7.62831  1.000 20.10846  ? 384 LEU A C    1 
ATOM   5901 O  O    . LEU A 1 404 ? 8.62917   -15.59117 -7.71007  1.000 20.76179  ? 384 LEU A O    1 
ATOM   5902 C  CB   . LEU A 1 404 ? 6.16957   -16.83316 -9.16491  1.000 22.05414  ? 384 LEU A CB   1 
ATOM   5903 C  CG   . LEU A 1 404 ? 4.99994   -17.09672 -10.13468 1.000 21.00335  ? 384 LEU A CG   1 
ATOM   5904 C  CD1  . LEU A 1 404 ? 5.04129   -18.55279 -10.68938 1.000 24.67005  ? 384 LEU A CD1  1 
ATOM   5905 C  CD2  . LEU A 1 404 ? 3.72246   -16.84822 -9.35992  1.000 24.84942  ? 384 LEU A CD2  1 
ATOM   5906 H  H    . LEU A 1 404 ? 7.30678   -15.29661 -10.66873 1.000 22.29959  ? 384 LEU A H    1 
ATOM   5907 H  HA   . LEU A 1 404 ? 5.70541   -14.86603 -8.64976  1.000 25.26839  ? 384 LEU A HA   1 
ATOM   5908 H  HB2  . LEU A 1 404 ? 6.95663   -17.24641 -9.55308  1.000 26.48873  ? 384 LEU A HB2  1 
ATOM   5909 H  HB3  . LEU A 1 404 ? 5.94533   -17.26819 -8.32743  1.000 26.48873  ? 384 LEU A HB3  1 
ATOM   5910 H  HG   . LEU A 1 404 ? 5.04949   -16.51284 -10.90767 1.000 25.22778  ? 384 LEU A HG   1 
ATOM   5911 H  HD11 . LEU A 1 404 ? 4.30242   -18.67714 -11.30543 1.000 29.62782  ? 384 LEU A HD11 1 
ATOM   5912 H  HD12 . LEU A 1 404 ? 5.88335   -18.69125 -11.15054 1.000 29.62782  ? 384 LEU A HD12 1 
ATOM   5913 H  HD13 . LEU A 1 404 ? 4.96323   -19.17500 -9.94934  1.000 29.62782  ? 384 LEU A HD13 1 
ATOM   5914 H  HD21 . LEU A 1 404 ? 2.96345   -17.04471 -9.93105  1.000 29.84306  ? 384 LEU A HD21 1 
ATOM   5915 H  HD22 . LEU A 1 404 ? 3.70832   -17.42568 -8.58067  1.000 29.84306  ? 384 LEU A HD22 1 
ATOM   5916 H  HD23 . LEU A 1 404 ? 3.69653   -15.91883 -9.08342  1.000 29.84306  ? 384 LEU A HD23 1 
ATOM   5917 N  N    . GLU A 1 405 ? 6.81783   -15.06788 -6.47484  1.000 21.52315  ? 385 GLU A N    1 
ATOM   5918 C  CA   . GLU A 1 405 ? 7.58345   -15.14125 -5.22414  1.000 22.58809  ? 385 GLU A CA   1 
ATOM   5919 C  C    . GLU A 1 405 ? 7.75350   -16.57235 -4.69673  1.000 25.36716  ? 385 GLU A C    1 
ATOM   5920 O  O    . GLU A 1 405 ? 8.75867   -16.87834 -4.02628  1.000 26.10719  ? 385 GLU A O    1 
ATOM   5921 C  CB   . GLU A 1 405 ? 6.90650   -14.30704 -4.12758  1.000 27.78309  ? 385 GLU A CB   1 
ATOM   5922 C  CG   . GLU A 1 405 ? 6.85024   -12.82836 -4.39792  1.000 29.72157  ? 385 GLU A CG   1 
ATOM   5923 C  CD   . GLU A 1 405 ? 6.27416   -12.04740 -3.21120  1.000 31.88555  ? 385 GLU A CD   1 
ATOM   5924 O  OE1  . GLU A 1 405 ? 5.87756   -12.65926 -2.17515  1.000 35.80662  ? 385 GLU A OE1  1 
ATOM   5925 O  OE2  . GLU A 1 405 ? 6.18563   -10.80477 -3.32063  1.000 39.06009  ? 385 GLU A OE2  1 
ATOM   5926 H  H    . GLU A 1 405 ? 5.99145   -14.84789 -6.38376  1.000 25.85154  ? 385 GLU A H    1 
ATOM   5927 H  HA   . GLU A 1 405 ? 8.46217   -14.77624 -5.41263  1.000 27.12947  ? 385 GLU A HA   1 
ATOM   5928 H  HB2  . GLU A 1 405 ? 5.99381   -14.61877 -4.02403  1.000 33.36347  ? 385 GLU A HB2  1 
ATOM   5929 H  HB3  . GLU A 1 405 ? 7.39604   -14.43300 -3.29970  1.000 33.36347  ? 385 GLU A HB3  1 
ATOM   5930 H  HG2  . GLU A 1 405 ? 7.74725   -12.50125 -4.56896  1.000 35.68965  ? 385 GLU A HG2  1 
ATOM   5931 H  HG3  . GLU A 1 405 ? 6.28537   -12.66671 -5.16973  1.000 35.68965  ? 385 GLU A HG3  1 
ATOM   5932 N  N    . SER A 1 406 ? 6.78001   -17.45186 -4.93195  1.000 22.87241  ? 386 SER A N    1 
ATOM   5933 C  CA   . SER A 1 406 ? 6.73553   -18.76837 -4.28708  1.000 24.52287  ? 386 SER A CA   1 
ATOM   5934 C  C    . SER A 1 406 ? 5.84314   -19.63535 -5.17634  1.000 24.87304  ? 386 SER A C    1 
ATOM   5935 O  O    . SER A 1 406 ? 4.95766   -19.11540 -5.83952  1.000 25.13837  ? 386 SER A O    1 
ATOM   5936 C  CB   . SER A 1 406 ? 6.13892   -18.68680 -2.86239  1.000 28.33838  ? 386 SER A CB   1 
ATOM   5937 O  OG   . SER A 1 406 ? 5.93550   -19.97856 -2.30853  1.000 32.20976  ? 386 SER A OG   1 
ATOM   5938 H  H    . SER A 1 406 ? 6.12301   -17.31005 -5.46845  1.000 27.47066  ? 386 SER A H    1 
ATOM   5939 H  HA   . SER A 1 406 ? 7.62346   -19.15131 -4.21060  1.000 29.45121  ? 386 SER A HA   1 
ATOM   5940 H  HB2  . SER A 1 406 ? 6.75215   -18.19533 -2.29379  1.000 34.02982  ? 386 SER A HB2  1 
ATOM   5941 H  HB3  . SER A 1 406 ? 5.28598   -18.22693 -2.90596  1.000 34.02982  ? 386 SER A HB3  1 
ATOM   5942 H  HG   . SER A 1 406 ? 6.66037   -20.40282 -2.29515  1.000 38.67548  ? 386 SER A HG   1 
ATOM   5943 N  N    . MET A 1 407 ? 6.11565   -20.95423 -5.23414  1.000 23.23434  ? 387 MET A N    1 
ATOM   5944 C  CA   A MET A 1 407 ? 5.31169   -21.85653 -6.05920  0.680 23.63502  ? 387 MET A CA   1 
ATOM   5945 C  CA   B MET A 1 407 ? 5.29494   -21.85599 -6.05417  0.320 23.64370  ? 387 MET A CA   1 
ATOM   5946 C  C    . MET A 1 407 ? 5.41896   -23.24727 -5.44854  1.000 22.20781  ? 387 MET A C    1 
ATOM   5947 O  O    . MET A 1 407 ? 6.19012   -24.09661 -5.92473  1.000 21.76121  ? 387 MET A O    1 
ATOM   5948 C  CB   A MET A 1 407 ? 5.78596   -21.86557 -7.51151  0.680 23.19894  ? 387 MET A CB   1 
ATOM   5949 C  CB   B MET A 1 407 ? 5.68555   -21.81805 -7.53291  0.320 23.19175  ? 387 MET A CB   1 
ATOM   5950 C  CG   A MET A 1 407 ? 4.94462   -22.73014 -8.43720  0.680 20.37941  ? 387 MET A CG   1 
ATOM   5951 C  CG   B MET A 1 407 ? 4.44628   -21.84457 -8.50545  0.320 26.12841  ? 387 MET A CG   1 
ATOM   5952 S  SD   A MET A 1 407 ? 5.55294   -22.32659 -10.13351 0.680 27.62079  ? 387 MET A SD   1 
ATOM   5953 S  SD   B MET A 1 407 ? 4.49311   -22.70250 -10.12346 0.320 23.38821  ? 387 MET A SD   1 
ATOM   5954 C  CE   A MET A 1 407 ? 5.88883   -23.93567 -10.74117 0.680 19.79816  ? 387 MET A CE   1 
ATOM   5955 C  CE   B MET A 1 407 ? 6.25769   -22.56895 -10.42995 0.320 18.97369  ? 387 MET A CE   1 
ATOM   5956 H  H    . MET A 1 407 ? 6.75562   -21.33750 -4.80618  1.000 27.90497  ? 387 MET A H    1 
ATOM   5957 H  HA   . MET A 1 407 ? 4.38774   -21.56119 -6.05879  1.000 28.39620  ? 387 MET A HA   1 
ATOM   5958 H  HB2  A MET A 1 407 ? 5.75925   -20.95768 -7.85199  0.680 27.86249  ? 387 MET A HB2  1 
ATOM   5959 H  HB2  B MET A 1 407 ? 6.18236   -21.00295 -7.70521  0.320 27.85387  ? 387 MET A HB2  1 
ATOM   5960 H  HB3  A MET A 1 407 ? 6.69479   -22.20350 -7.53872  0.680 27.86249  ? 387 MET A HB3  1 
ATOM   5961 H  HB3  B MET A 1 407 ? 6.23699   -22.59095 -7.73153  0.320 27.85387  ? 387 MET A HB3  1 
ATOM   5962 H  HG2  A MET A 1 407 ? 5.07993   -23.67219 -8.24975  0.680 24.47906  ? 387 MET A HG2  1 
ATOM   5963 H  HG2  B MET A 1 407 ? 3.71632   -22.25514 -8.01608  0.320 31.37785  ? 387 MET A HG2  1 
ATOM   5964 H  HG3  A MET A 1 407 ? 4.00364   -22.50809 -8.35878  0.680 24.47906  ? 387 MET A HG3  1 
ATOM   5965 H  HG3  B MET A 1 407 ? 4.23131   -20.92079 -8.70869  0.320 31.37785  ? 387 MET A HG3  1 
ATOM   5966 H  HE1  A MET A 1 407 ? 6.19187   -23.86928 -11.66022 0.680 23.78155  ? 387 MET A HE1  1 
ATOM   5967 H  HE1  B MET A 1 407 ? 6.43670   -22.80628 -11.35328 0.320 22.79220  ? 387 MET A HE1  1 
ATOM   5968 H  HE2  A MET A 1 407 ? 6.57883   -24.34225 -10.19391 0.680 23.78155  ? 387 MET A HE2  1 
ATOM   5969 H  HE2  B MET A 1 407 ? 6.53907   -21.65587 -10.26260 0.320 22.79220  ? 387 MET A HE2  1 
ATOM   5970 H  HE3  A MET A 1 407 ? 5.07737   -24.46535 -10.69788 0.680 23.78155  ? 387 MET A HE3  1 
ATOM   5971 H  HE3  B MET A 1 407 ? 6.72814   -23.17425 -9.83566  0.320 22.79220  ? 387 MET A HE3  1 
ATOM   5972 N  N    . PRO A 1 408 ? 4.64846   -23.52946 -4.39538  1.000 21.38900  ? 388 PRO A N    1 
ATOM   5973 C  CA   . PRO A 1 408 ? 4.65596   -24.88040 -3.80056  1.000 24.06382  ? 388 PRO A CA   1 
ATOM   5974 C  C    . PRO A 1 408 ? 4.12917   -25.91867 -4.78794  1.000 25.53563  ? 388 PRO A C    1 
ATOM   5975 O  O    . PRO A 1 408 ? 3.08262   -25.72634 -5.42031  1.000 24.19097  ? 388 PRO A O    1 
ATOM   5976 C  CB   . PRO A 1 408 ? 3.72985   -24.74933 -2.57518  1.000 26.06723  ? 388 PRO A CB   1 
ATOM   5977 C  CG   . PRO A 1 408 ? 3.72567   -23.29530 -2.25280  1.000 28.64016  ? 388 PRO A CG   1 
ATOM   5978 C  CD   . PRO A 1 408 ? 3.83065   -22.58692 -3.58424  1.000 25.98060  ? 388 PRO A CD   1 
ATOM   5979 H  HA   . PRO A 1 408 ? 5.55063   -25.11785 -3.51059  1.000 28.90035  ? 388 PRO A HA   1 
ATOM   5980 H  HB2  . PRO A 1 408 ? 2.83822   -25.05804 -2.80008  1.000 31.30444  ? 388 PRO A HB2  1 
ATOM   5981 H  HB3  . PRO A 1 408 ? 4.08399   -25.26820 -1.83608  1.000 31.30444  ? 388 PRO A HB3  1 
ATOM   5982 H  HG2  . PRO A 1 408 ? 2.89960   -23.06099 -1.80157  1.000 34.39196  ? 388 PRO A HG2  1 
ATOM   5983 H  HG3  . PRO A 1 408 ? 4.48453   -23.08170 -1.68763  1.000 34.39196  ? 388 PRO A HG3  1 
ATOM   5984 H  HD2  . PRO A 1 408 ? 2.95411   -22.45912 -3.97953  1.000 31.20049  ? 388 PRO A HD2  1 
ATOM   5985 H  HD3  . PRO A 1 408 ? 4.27913   -21.73219 -3.48830  1.000 31.20049  ? 388 PRO A HD3  1 
ATOM   5986 N  N    . VAL A 1 409 ? 4.87145   -27.02028 -4.91315  1.000 25.19974  ? 389 VAL A N    1 
ATOM   5987 C  CA   . VAL A 1 409 ? 4.54531   -28.11453 -5.82667  1.000 23.76124  ? 389 VAL A CA   1 
ATOM   5988 C  C    . VAL A 1 409 ? 4.75679   -29.44969 -5.11734  1.000 24.47763  ? 389 VAL A C    1 
ATOM   5989 O  O    . VAL A 1 409 ? 5.57302   -29.56740 -4.19340  1.000 26.49497  ? 389 VAL A O    1 
ATOM   5990 C  CB   . VAL A 1 409 ? 5.39462   -28.04777 -7.13710  1.000 24.21703  ? 389 VAL A CB   1 
ATOM   5991 C  CG1  . VAL A 1 409 ? 5.03170   -26.84803 -7.97120  1.000 22.96135  ? 389 VAL A CG1  1 
ATOM   5992 C  CG2  . VAL A 1 409 ? 6.91093   -28.07529 -6.84270  1.000 23.29149  ? 389 VAL A CG2  1 
ATOM   5993 H  H    . VAL A 1 409 ? 5.59177   -27.16059 -4.46476  1.000 30.26344  ? 389 VAL A H    1 
ATOM   5994 H  HA   . VAL A 1 409 ? 3.60679   -28.05237 -6.06378  1.000 28.53725  ? 389 VAL A HA   1 
ATOM   5995 H  HB   . VAL A 1 409 ? 5.18623   -28.84096 -7.65510  1.000 29.08419  ? 389 VAL A HB   1 
ATOM   5996 H  HG11 . VAL A 1 409 ? 5.57174   -26.84855 -8.77696  1.000 27.57738  ? 389 VAL A HG11 1 
ATOM   5997 H  HG12 . VAL A 1 409 ? 4.09119   -26.89761 -8.20333  1.000 27.57738  ? 389 VAL A HG12 1 
ATOM   5998 H  HG13 . VAL A 1 409 ? 5.20379   -26.04299 -7.45817  1.000 27.57738  ? 389 VAL A HG13 1 
ATOM   5999 H  HG21 . VAL A 1 409 ? 7.39570   -27.91405 -7.66726  1.000 27.97355  ? 389 VAL A HG21 1 
ATOM   6000 H  HG22 . VAL A 1 409 ? 7.11960   -27.38346 -6.19561  1.000 27.97355  ? 389 VAL A HG22 1 
ATOM   6001 H  HG23 . VAL A 1 409 ? 7.14738   -28.94525 -6.48469  1.000 27.97355  ? 389 VAL A HG23 1 
ATOM   6002 N  N    . VAL A 1 410 ? 3.99878   -30.47212 -5.54169  1.000 24.44196  ? 390 VAL A N    1 
ATOM   6003 C  CA   . VAL A 1 410 ? 4.13825   -31.83418 -5.03377  1.000 24.42047  ? 390 VAL A CA   1 
ATOM   6004 C  C    . VAL A 1 410 ? 4.36118   -32.78041 -6.20775  1.000 25.69598  ? 390 VAL A C    1 
ATOM   6005 O  O    . VAL A 1 410 ? 4.05022   -32.45496 -7.35770  1.000 27.96780  ? 390 VAL A O    1 
ATOM   6006 C  CB   . VAL A 1 410 ? 2.93675   -32.29909 -4.17467  1.000 28.86371  ? 390 VAL A CB   1 
ATOM   6007 C  CG1  . VAL A 1 410 ? 2.93230   -31.53919 -2.84726  1.000 28.37282  ? 390 VAL A CG1  1 
ATOM   6008 C  CG2  . VAL A 1 410 ? 1.65083   -32.12458 -4.93718  1.000 29.38064  ? 390 VAL A CG2  1 
ATOM   6009 H  H    . VAL A 1 410 ? 3.38376   -30.39391 -6.13771  1.000 29.35412  ? 390 VAL A H    1 
ATOM   6010 H  HA   . VAL A 1 410 ? 4.92424   -31.86285 -4.46606  1.000 29.32832  ? 390 VAL A HA   1 
ATOM   6011 H  HB   . VAL A 1 410 ? 3.01528   -33.24418 -3.97085  1.000 34.66022  ? 390 VAL A HB   1 
ATOM   6012 H  HG11 . VAL A 1 410 ? 2.16415   -31.81951 -2.32547  1.000 34.07115  ? 390 VAL A HG11 1 
ATOM   6013 H  HG12 . VAL A 1 410 ? 3.75018   -31.73970 -2.36584  1.000 34.07115  ? 390 VAL A HG12 1 
ATOM   6014 H  HG13 . VAL A 1 410 ? 2.87981   -30.58767 -3.02826  1.000 34.07115  ? 390 VAL A HG13 1 
ATOM   6015 H  HG21 . VAL A 1 410 ? 0.90930   -32.38906 -4.37054  1.000 35.28054  ? 390 VAL A HG21 1 
ATOM   6016 H  HG22 . VAL A 1 410 ? 1.55774   -31.19284 -5.19033  1.000 35.28054  ? 390 VAL A HG22 1 
ATOM   6017 H  HG23 . VAL A 1 410 ? 1.67602   -32.68200 -5.73062  1.000 35.28054  ? 390 VAL A HG23 1 
ATOM   6018 N  N    . PHE A 1 411 ? 4.88971   -33.97185 -5.88603  1.000 27.26286  ? 391 PHE A N    1 
ATOM   6019 C  CA   . PHE A 1 411 ? 5.31791   -34.97098 -6.86056  1.000 28.58236  ? 391 PHE A CA   1 
ATOM   6020 C  C    . PHE A 1 411 ? 5.60461   -36.27249 -6.12475  1.000 29.44423  ? 391 PHE A C    1 
ATOM   6021 O  O    . PHE A 1 411 ? 5.90858   -36.28005 -4.92698  1.000 32.09364  ? 391 PHE A O    1 
ATOM   6022 C  CB   . PHE A 1 411 ? 6.56842   -34.50355 -7.63297  1.000 27.19884  ? 391 PHE A CB   1 
ATOM   6023 C  CG   . PHE A 1 411 ? 7.69669   -34.05505 -6.75157  1.000 27.55482  ? 391 PHE A CG   1 
ATOM   6024 C  CD1  . PHE A 1 411 ? 8.62689   -34.97941 -6.29242  1.000 27.53078  ? 391 PHE A CD1  1 
ATOM   6025 C  CD2  . PHE A 1 411 ? 7.82565   -32.72997 -6.38467  1.000 25.89170  ? 391 PHE A CD2  1 
ATOM   6026 C  CE1  . PHE A 1 411 ? 9.67872   -34.59098 -5.46658  1.000 27.95678  ? 391 PHE A CE1  1 
ATOM   6027 C  CE2  . PHE A 1 411 ? 8.89014   -32.32257 -5.55146  1.000 27.29247  ? 391 PHE A CE2  1 
ATOM   6028 C  CZ   . PHE A 1 411 ? 9.79983   -33.28013 -5.08935  1.000 27.63558  ? 391 PHE A CZ   1 
ATOM   6029 H  H    . PHE A 1 411 ? 5.01311   -34.22984 -5.07498  1.000 32.73919  ? 391 PHE A H    1 
ATOM   6030 H  HA   . PHE A 1 411 ? 4.60253   -35.13032 -7.49596  1.000 34.32259  ? 391 PHE A HA   1 
ATOM   6031 H  HB2  . PHE A 1 411 ? 6.89223   -35.23965 -8.17537  1.000 32.66237  ? 391 PHE A HB2  1 
ATOM   6032 H  HB3  . PHE A 1 411 ? 6.32228   -33.75643 -8.20053  1.000 32.66237  ? 391 PHE A HB3  1 
ATOM   6033 H  HD1  . PHE A 1 411 ? 8.54575   -35.87199 -6.54065  1.000 33.06069  ? 391 PHE A HD1  1 
ATOM   6034 H  HD2  . PHE A 1 411 ? 7.20880   -32.10341 -6.68766  1.000 31.09380  ? 391 PHE A HD2  1 
ATOM   6035 H  HE1  . PHE A 1 411 ? 10.29716  -35.22003 -5.17207  1.000 33.57189  ? 391 PHE A HE1  1 
ATOM   6036 H  HE2  . PHE A 1 411 ? 8.98555   -31.42882 -5.31269  1.000 32.77473  ? 391 PHE A HE2  1 
ATOM   6037 H  HZ   . PHE A 1 411 ? 10.49125  -33.02464 -4.52230  1.000 33.18646  ? 391 PHE A HZ   1 
ATOM   6038 N  N    . THR A 1 412 ? 5.51994   -37.37867 -6.84520  1.000 31.30610  ? 392 THR A N    1 
ATOM   6039 C  CA   . THR A 1 412 ? 5.91007   -38.64630 -6.26611  1.000 32.99597  ? 392 THR A CA   1 
ATOM   6040 C  C    . THR A 1 412 ? 7.41803   -38.67103 -6.02750  1.000 33.16005  ? 392 THR A C    1 
ATOM   6041 O  O    . THR A 1 412 ? 8.19665   -38.37545 -6.94803  1.000 35.30520  ? 392 THR A O    1 
ATOM   6042 C  CB   . THR A 1 412 ? 5.48325   -39.80658 -7.15171  1.000 32.57065  ? 392 THR A CB   1 
ATOM   6043 O  OG1  . THR A 1 412 ? 4.05252   -39.81449 -7.26606  1.000 34.98685  ? 392 THR A OG1  1 
ATOM   6044 C  CG2  . THR A 1 412 ? 5.95729   -41.11806 -6.55986  1.000 35.01861  ? 392 THR A CG2  1 
ATOM   6045 H  H    . THR A 1 412 ? 5.24397   -37.41985 -7.65868  1.000 37.59108  ? 392 THR A H    1 
ATOM   6046 H  HA   . THR A 1 412 ? 5.46500   -38.75508 -5.41113  1.000 39.61892  ? 392 THR A HA   1 
ATOM   6047 H  HB   . THR A 1 412 ? 5.87445   -39.71270 -8.03435  1.000 39.10854  ? 392 THR A HB   1 
ATOM   6048 H  HG1  . THR A 1 412 ? 3.78331   -39.07317 -7.55513  1.000 42.00798  ? 392 THR A HG1  1 
ATOM   6049 H  HG21 . THR A 1 412 ? 5.51361   -41.86012 -6.99964  1.000 42.04610  ? 392 THR A HG21 1 
ATOM   6050 H  HG22 . THR A 1 412 ? 6.91562   -41.20879 -6.67929  1.000 42.04610  ? 392 THR A HG22 1 
ATOM   6051 H  HG23 . THR A 1 412 ? 5.75408   -41.14691 -5.61183  1.000 42.04610  ? 392 THR A HG23 1 
ATOM   6052 N  N    . PRO A 1 413 ? 7.86478   -39.01460 -4.81535  1.000 33.46658  ? 393 PRO A N    1 
ATOM   6053 C  CA   . PRO A 1 413 ? 9.29987   -39.03066 -4.52541  1.000 35.12163  ? 393 PRO A CA   1 
ATOM   6054 C  C    . PRO A 1 413 ? 10.03182  -40.07054 -5.35866  1.000 39.85686  ? 393 PRO A C    1 
ATOM   6055 O  O    . PRO A 1 413 ? 9.46982   -41.08187 -5.79072  1.000 41.54998  ? 393 PRO A O    1 
ATOM   6056 C  CB   . PRO A 1 413 ? 9.36495   -39.39681 -3.03539  1.000 37.41654  ? 393 PRO A CB   1 
ATOM   6057 C  CG   . PRO A 1 413 ? 8.04615   -39.03775 -2.48525  1.000 44.77369  ? 393 PRO A CG   1 
ATOM   6058 C  CD   . PRO A 1 413 ? 7.06002   -39.26580 -3.60513  1.000 35.62757  ? 393 PRO A CD   1 
ATOM   6059 H  HA   . PRO A 1 413 ? 9.68272   -38.15198 -4.67460  1.000 42.16972  ? 393 PRO A HA   1 
ATOM   6060 H  HB2  . PRO A 1 413 ? 9.53291   -40.34717 -2.93785  1.000 44.92362  ? 393 PRO A HB2  1 
ATOM   6061 H  HB3  . PRO A 1 413 ? 10.06951  -38.88930 -2.60303  1.000 44.92362  ? 393 PRO A HB3  1 
ATOM   6062 H  HG2  . PRO A 1 413 ? 7.84203   -39.60599 -1.72607  1.000 53.75219  ? 393 PRO A HG2  1 
ATOM   6063 H  HG3  . PRO A 1 413 ? 8.04738   -38.10700 -2.21214  1.000 53.75219  ? 393 PRO A HG3  1 
ATOM   6064 H  HD2  . PRO A 1 413 ? 6.72790   -40.17710 -3.59347  1.000 42.77684  ? 393 PRO A HD2  1 
ATOM   6065 H  HD3  . PRO A 1 413 ? 6.31949   -38.64204 -3.54642  1.000 42.77684  ? 393 PRO A HD3  1 
ATOM   6066 N  N    . SER A 1 414 ? 11.32444  -39.83189 -5.52691  1.000 39.02847  ? 394 SER A N    1 
ATOM   6067 C  CA   . SER A 1 414 ? 12.20719  -40.73038 -6.25368  1.000 42.16070  ? 394 SER A CA   1 
ATOM   6068 C  C    . SER A 1 414 ? 13.59684  -40.63426 -5.65144  1.000 43.75482  ? 394 SER A C    1 
ATOM   6069 O  O    . SER A 1 414 ? 13.90437  -39.67995 -4.92787  1.000 40.38683  ? 394 SER A O    1 
ATOM   6070 C  CB   . SER A 1 414 ? 12.24289  -40.38821 -7.74727  1.000 41.95278  ? 394 SER A CB   1 
ATOM   6071 O  OG   . SER A 1 414 ? 12.78629  -39.07580 -7.95459  1.000 41.14562  ? 394 SER A OG   1 
ATOM   6072 H  H    . SER A 1 414 ? 11.72529  -39.13553 -5.22033  1.000 46.85792  ? 394 SER A H    1 
ATOM   6073 H  HA   . SER A 1 414 ? 11.89762  -41.64437 -6.15526  1.000 50.61660  ? 394 SER A HA   1 
ATOM   6074 H  HB2  . SER A 1 414 ? 12.79848  -41.03685 -8.20715  1.000 50.36709  ? 394 SER A HB2  1 
ATOM   6075 H  HB3  . SER A 1 414 ? 11.33963  -40.41586 -8.09976  1.000 50.36709  ? 394 SER A HB3  1 
ATOM   6076 H  HG   . SER A 1 414 ? 12.36644  -38.51458 -7.49161  1.000 49.39850  ? 394 SER A HG   1 
ATOM   6077 N  N    . PRO A 1 415 ? 14.44819  -41.61926 -5.90141  1.000 41.73882  ? 395 PRO A N    1 
ATOM   6078 C  CA   . PRO A 1 415 ? 15.81207  -41.57376 -5.36811  1.000 41.72704  ? 395 PRO A CA   1 
ATOM   6079 C  C    . PRO A 1 415 ? 16.68268  -40.63308 -6.17624  1.000 40.05348  ? 395 PRO A C    1 
ATOM   6080 O  O    . PRO A 1 415 ? 16.47740  -40.47713 -7.38981  1.000 44.76725  ? 395 PRO A O    1 
ATOM   6081 C  CB   . PRO A 1 415 ? 16.30934  -43.02213 -5.50098  1.000 47.21122  ? 395 PRO A CB   1 
ATOM   6082 C  CG   . PRO A 1 415 ? 15.24726  -43.78984 -6.15912  1.000 51.36147  ? 395 PRO A CG   1 
ATOM   6083 C  CD   . PRO A 1 415 ? 14.05616  -42.94624 -6.40611  1.000 45.63379  ? 395 PRO A CD   1 
ATOM   6084 H  HA   . PRO A 1 415 ? 15.80298  -41.30965 -4.43480  1.000 50.09620  ? 395 PRO A HA   1 
ATOM   6085 H  HB2  . PRO A 1 415 ? 17.11823  -43.03557 -6.03617  1.000 56.67722  ? 395 PRO A HB2  1 
ATOM   6086 H  HB3  . PRO A 1 415 ? 16.48960  -43.38148 -4.61822  1.000 56.67722  ? 395 PRO A HB3  1 
ATOM   6087 H  HG2  . PRO A 1 415 ? 15.58936  -44.12286 -7.00349  1.000 61.65753  ? 395 PRO A HG2  1 
ATOM   6088 H  HG3  . PRO A 1 415 ? 15.00511  -44.53200 -5.58340  1.000 61.65753  ? 395 PRO A HG3  1 
ATOM   6089 H  HD2  . PRO A 1 415 ? 13.85530  -42.90644 -7.35425  1.000 54.78431  ? 395 PRO A HD2  1 
ATOM   6090 H  HD3  . PRO A 1 415 ? 13.28925  -43.28529 -5.91846  1.000 54.78431  ? 395 PRO A HD3  1 
ATOM   6091 N  N    . PRO A 1 416 ? 17.68794  -40.02040 -5.55080  1.000 38.80852  ? 396 PRO A N    1 
ATOM   6092 C  CA   . PRO A 1 416 ? 18.57861  -39.11684 -6.29569  1.000 40.38848  ? 396 PRO A CA   1 
ATOM   6093 C  C    . PRO A 1 416 ? 19.50189  -39.88080 -7.23884  1.000 47.22454  ? 396 PRO A C    1 
ATOM   6094 O  O    . PRO A 1 416 ? 19.67715  -41.10060 -7.15362  1.000 45.15691  ? 396 PRO A O    1 
ATOM   6095 C  CB   . PRO A 1 416 ? 19.37137  -38.40467 -5.19697  1.000 36.82960  ? 396 PRO A CB   1 
ATOM   6096 C  CG   . PRO A 1 416 ? 19.33142  -39.36252 -4.03382  1.000 46.66084  ? 396 PRO A CG   1 
ATOM   6097 C  CD   . PRO A 1 416 ? 17.99736  -40.05006 -4.10748  1.000 44.61357  ? 396 PRO A CD   1 
ATOM   6098 H  HA   . PRO A 1 416 ? 18.06057  -38.47088 -6.80094  1.000 48.48994  ? 396 PRO A HA   1 
ATOM   6099 H  HB2  . PRO A 1 416 ? 20.28248  -38.24850 -5.49089  1.000 44.21928  ? 396 PRO A HB2  1 
ATOM   6100 H  HB3  . PRO A 1 416 ? 18.94645  -37.56230 -4.97169  1.000 44.21928  ? 396 PRO A HB3  1 
ATOM   6101 H  HG2  . PRO A 1 416 ? 20.05331  -40.00526 -4.11541  1.000 56.01677  ? 396 PRO A HG2  1 
ATOM   6102 H  HG3  . PRO A 1 416 ? 19.41793  -38.87021 -3.20253  1.000 56.01677  ? 396 PRO A HG3  1 
ATOM   6103 H  HD2  . PRO A 1 416 ? 18.05986  -40.96286 -3.78532  1.000 53.56004  ? 396 PRO A HD2  1 
ATOM   6104 H  HD3  . PRO A 1 416 ? 17.32874  -39.56412 -3.59983  1.000 53.56004  ? 396 PRO A HD3  1 
ATOM   6105 N  N    . LEU A 1 417 ? 20.10848  -39.12134 -8.14624  1.000 45.85604  ? 397 LEU A N    1 
ATOM   6106 C  CA   . LEU A 1 417 ? 21.11092  -39.64842 -9.05841  1.000 48.28633  ? 397 LEU A CA   1 
ATOM   6107 C  C    . LEU A 1 417 ? 22.50381  -39.43331 -8.47223  1.000 46.79533  ? 397 LEU A C    1 
ATOM   6108 O  O    . LEU A 1 417 ? 23.38689  -40.28339 -8.67511  1.000 59.16247  ? 397 LEU A O    1 
ATOM   6109 C  CB   . LEU A 1 417 ? 21.01483  -38.97215 -10.40978 1.000 41.46028  ? 397 LEU A CB   1 
ATOM   6110 C  CG   . LEU A 1 417 ? 19.65828  -38.96324 -11.10881 1.000 48.27167  ? 397 LEU A CG   1 
ATOM   6111 C  CD1  . LEU A 1 417 ? 19.77841  -38.21414 -12.43632 1.000 47.51751  ? 397 LEU A CD1  1 
ATOM   6112 C  CD2  . LEU A 1 417 ? 19.14000  -40.37480 -11.31339 1.000 52.59223  ? 397 LEU A CD2  1 
ATOM   6113 H  H    . LEU A 1 417 ? 19.95248  -38.28247 -8.25374  1.000 55.05101  ? 397 LEU A H    1 
ATOM   6114 H  HA   . LEU A 1 417 ? 20.96225  -40.59759 -9.19208  1.000 57.96736  ? 397 LEU A HA   1 
ATOM   6115 H  HB2  . LEU A 1 417 ? 21.27551  -38.04494 -10.29476 1.000 49.77610  ? 397 LEU A HB2  1 
ATOM   6116 H  HB3  . LEU A 1 417 ? 21.63399  -39.41909 -11.00793 1.000 49.77610  ? 397 LEU A HB3  1 
ATOM   6117 H  HG   . LEU A 1 417 ? 19.00689  -38.50561 -10.55458 1.000 57.94977  ? 397 LEU A HG   1 
ATOM   6118 H  HD11 . LEU A 1 417 ? 18.91299  -38.20708 -12.87438 1.000 57.04478  ? 397 LEU A HD11 1 
ATOM   6119 H  HD12 . LEU A 1 417 ? 20.06778  -37.30508 -12.26089 1.000 57.04478  ? 397 LEU A HD12 1 
ATOM   6120 H  HD13 . LEU A 1 417 ? 20.42890  -38.66610 -12.99622 1.000 57.04478  ? 397 LEU A HD13 1 
ATOM   6121 H  HD21 . LEU A 1 417 ? 18.31410  -40.33754 -11.82072 1.000 63.13444  ? 397 LEU A HD21 1 
ATOM   6122 H  HD22 . LEU A 1 417 ? 19.80421  -40.88767 -11.79990 1.000 63.13444  ? 397 LEU A HD22 1 
ATOM   6123 H  HD23 . LEU A 1 417 ? 18.97815  -40.78041 -10.44726 1.000 63.13444  ? 397 LEU A HD23 1 
HETATM 6124 C  CAA  . 3QO B 2 .   ? 21.39169  -2.67018  -15.26174 1.000 26.70833  ? 401 3QO A CAA  1 
HETATM 6125 C  CAB  . 3QO B 2 .   ? 20.48299  -2.86112  -16.26608 1.000 22.54176  ? 401 3QO A CAB  1 
HETATM 6126 C  CAC  . 3QO B 2 .   ? 21.57708  -3.63861  -14.31357 1.000 27.88277  ? 401 3QO A CAC  1 
HETATM 6127 C  CAD  . 3QO B 2 .   ? 18.11925  -8.21973  -18.52827 1.000 17.68084  ? 401 3QO A CAD  1 
HETATM 6128 C  CAE  . 3QO B 2 .   ? 20.37989  -8.40919  -18.27930 1.000 19.95374  ? 401 3QO A CAE  1 
HETATM 6129 C  CAF  . 3QO B 2 .   ? 19.75237  -4.03649  -16.34703 1.000 21.91507  ? 401 3QO A CAF  1 
HETATM 6130 C  CAG  . 3QO B 2 .   ? 20.83113  -4.80696  -14.37675 1.000 28.23011  ? 401 3QO A CAG  1 
HETATM 6131 C  CAH  . 3QO B 2 .   ? 18.00675  -7.44134  -17.39532 1.000 19.76125  ? 401 3QO A CAH  1 
HETATM 6132 C  CAI  . 3QO B 2 .   ? 20.36559  -7.63829  -17.14113 1.000 20.23157  ? 401 3QO A CAI  1 
HETATM 6133 C  CAJ  . 3QO B 2 .   ? 19.09395  -6.29489  -15.43441 1.000 23.37817  ? 401 3QO A CAJ  1 
HETATM 6134 N  NAK  . 3QO B 2 .   ? 19.28364  -8.69413  -18.98525 1.000 18.71089  ? 401 3QO A NAK  1 
HETATM 6135 C  CAL  . 3QO B 2 .   ? 19.91620  -5.02530  -15.39234 1.000 21.57824  ? 401 3QO A CAL  1 
HETATM 6136 C  CAM  . 3QO B 2 .   ? 19.15838  -7.12981  -16.68948 1.000 21.50538  ? 401 3QO A CAM  1 
HETATM 6137 H  HAA  . 3QO B 2 .   ? 21.89098  -1.86997  -15.22290 1.000 32.07376  ? 401 3QO A HAA  1 
HETATM 6138 H  HAB  . 3QO B 2 .   ? 20.35135  -2.18524  -16.91182 1.000 27.07388  ? 401 3QO A HAB  1 
HETATM 6139 H  HAC  . 3QO B 2 .   ? 22.20709  -3.51379  -13.62173 1.000 33.48308  ? 401 3QO A HAC  1 
HETATM 6140 H  HAD  . 3QO B 2 .   ? 17.33529  -8.43025  -19.00820 1.000 21.24077  ? 401 3QO A HAD  1 
HETATM 6141 H  HAE  . 3QO B 2 .   ? 21.20444  -8.75535  -18.57852 1.000 23.96825  ? 401 3QO A HAE  1 
HETATM 6142 H  HAF  . 3QO B 2 .   ? 19.14069  -4.16516  -17.05444 1.000 26.32185  ? 401 3QO A HAF  1 
HETATM 6143 H  HAG  . 3QO B 2 .   ? 20.94838  -5.46875  -13.71386 1.000 33.89989  ? 401 3QO A HAG  1 
HETATM 6144 H  HAH  . 3QO B 2 .   ? 17.16716  -7.12354  -17.10017 1.000 23.73726  ? 401 3QO A HAH  1 
HETATM 6145 H  HAI  . 3QO B 2 .   ? 21.16255  -7.45332  -16.66819 1.000 24.30164  ? 401 3QO A HAI  1 
HETATM 6146 H  HAJ  . 3QO B 2 .   ? 18.15397  -6.04846  -15.28609 1.000 28.07756  ? 401 3QO A HAJ  1 
HETATM 6147 H  HAJA . 3QO B 2 .   ? 19.37786  -6.86110  -14.68268 1.000 28.07756  ? 401 3QO A HAJA 1 
HETATM 6148 C  CAD  . 3QO C 2 .   ? 22.27659  -1.17107  -9.92390  1.000 44.50762  ? 402 3QO A CAD  1 
HETATM 6149 C  CAE  . 3QO C 2 .   ? 24.34856  -1.34135  -10.84173 1.000 50.89256  ? 402 3QO A CAE  1 
HETATM 6150 C  CAH  . 3QO C 2 .   ? 22.71417  -0.26548  -8.98274  1.000 46.32793  ? 402 3QO A CAH  1 
HETATM 6151 C  CAI  . 3QO C 2 .   ? 24.87686  -0.45302  -9.93080  1.000 48.42325  ? 402 3QO A CAI  1 
HETATM 6152 C  CAJ  . 3QO C 2 .   ? 24.58390  1.08433   -7.95016  1.000 51.07563  ? 402 3QO A CAJ  1 
HETATM 6153 N  NAK  . 3QO C 2 .   ? 23.06719  -1.71024  -10.85192 1.000 48.17377  ? 402 3QO A NAK  1 
HETATM 6154 C  CAL  . 3QO C 2 .   ? 25.36045  2.22510   -8.57164  1.000 52.51549  ? 402 3QO A CAL  1 
HETATM 6155 C  CAM  . 3QO C 2 .   ? 24.04725  0.10352   -8.97328  1.000 47.38555  ? 402 3QO A CAM  1 
HETATM 6156 H  HAD  . 3QO C 2 .   ? 21.36855  -1.42525  -9.91340  1.000 53.43291  ? 402 3QO A HAD  1 
HETATM 6157 H  HAE  . 3QO C 2 .   ? 24.92148  -1.70967  -11.49391 1.000 61.09484  ? 402 3QO A HAE  1 
HETATM 6158 H  HAH  . 3QO C 2 .   ? 22.11826  0.10328   -8.34875  1.000 55.61728  ? 402 3QO A HAH  1 
HETATM 6159 H  HAI  . 3QO C 2 .   ? 25.79279  -0.22150  -9.95279  1.000 58.13166  ? 402 3QO A HAI  1 
HETATM 6160 H  HAJ  . 3QO C 2 .   ? 23.83164  1.45290   -7.43582  1.000 61.31452  ? 402 3QO A HAJ  1 
HETATM 6161 H  HAJA . 3QO C 2 .   ? 25.16906  0.60376   -7.32332  1.000 61.31452  ? 402 3QO A HAJA 1 
HETATM 6162 C  CHA  . HEM D 3 .   ? 19.89328  -6.81981  -22.35790 1.000 20.44301  ? 403 HEM A CHA  1 
HETATM 6163 C  CHB  . HEM D 3 .   ? 16.01743  -9.49875  -21.14009 1.000 18.35911  ? 403 HEM A CHB  1 
HETATM 6164 C  CHC  . HEM D 3 .   ? 18.92587  -12.86132 -19.31869 1.000 19.20558  ? 403 HEM A CHC  1 
HETATM 6165 C  CHD  . HEM D 3 .   ? 22.82043  -10.07276 -20.23780 1.000 19.25531  ? 403 HEM A CHD  1 
HETATM 6166 C  C1A  . HEM D 3 .   ? 18.59326  -7.24385  -22.18826 1.000 18.35478  ? 403 HEM A C1A  1 
HETATM 6167 C  C2A  . HEM D 3 .   ? 17.39396  -6.52606  -22.65939 1.000 19.97310  ? 403 HEM A C2A  1 
HETATM 6168 C  C3A  . HEM D 3 .   ? 16.34754  -7.30369  -22.33776 1.000 17.45598  ? 403 HEM A C3A  1 
HETATM 6169 C  C4A  . HEM D 3 .   ? 16.80650  -8.49651  -21.64894 1.000 18.35477  ? 403 HEM A C4A  1 
HETATM 6170 C  CMA  . HEM D 3 .   ? 14.87484  -6.95353  -22.51650 1.000 17.73878  ? 403 HEM A CMA  1 
HETATM 6171 C  CAA  . HEM D 3 .   ? 17.34748  -5.16751  -23.40089 1.000 19.39745  ? 403 HEM A CAA  1 
HETATM 6172 C  CBA  . HEM D 3 .   ? 16.84981  -5.37883  -24.84105 1.000 19.91419  ? 403 HEM A CBA  1 
HETATM 6173 C  CGA  . HEM D 3 .   ? 16.22652  -4.14419  -25.45623 1.000 22.38271  ? 403 HEM A CGA  1 
HETATM 6174 O  O1A  . HEM D 3 .   ? 15.85082  -4.27198  -26.64891 1.000 22.60077  ? 403 HEM A O1A  1 
HETATM 6175 O  O2A  . HEM D 3 .   ? 16.06711  -3.09897  -24.79288 1.000 21.78210  ? 403 HEM A O2A  1 
HETATM 6176 C  C1B  . HEM D 3 .   ? 16.48272  -10.62867 -20.54575 1.000 17.07761  ? 403 HEM A C1B  1 
HETATM 6177 C  C2B  . HEM D 3 .   ? 15.63616  -11.78003 -20.22040 1.000 17.97166  ? 403 HEM A C2B  1 
HETATM 6178 C  C3B  . HEM D 3 .   ? 16.46774  -12.70553 -19.70578 1.000 17.53534  ? 403 HEM A C3B  1 
HETATM 6179 C  C4B  . HEM D 3 .   ? 17.81438  -12.18837 -19.71331 1.000 18.11944  ? 403 HEM A C4B  1 
HETATM 6180 C  CMB  . HEM D 3 .   ? 14.11468  -11.82670 -20.38683 1.000 20.94543  ? 403 HEM A CMB  1 
HETATM 6181 C  CAB  . HEM D 3 .   ? 16.15564  -14.09798 -19.14895 1.000 18.29781  ? 403 HEM A CAB  1 
HETATM 6182 C  CBB  . HEM D 3 .   ? 15.09252  -14.79647 -19.55086 1.000 24.27871  ? 403 HEM A CBB  1 
HETATM 6183 C  C1C  . HEM D 3 .   ? 20.22158  -12.37515 -19.41737 1.000 18.84329  ? 403 HEM A C1C  1 
HETATM 6184 C  C2C  . HEM D 3 .   ? 21.38458  -13.14517 -19.01731 1.000 19.93256  ? 403 HEM A C2C  1 
HETATM 6185 C  C3C  . HEM D 3 .   ? 22.46739  -12.37709 -19.26196 1.000 20.12865  ? 403 HEM A C3C  1 
HETATM 6186 C  C4C  . HEM D 3 .   ? 22.02288  -11.12377 -19.82859 1.000 18.76510  ? 403 HEM A C4C  1 
HETATM 6187 C  CMC  . HEM D 3 .   ? 21.37007  -14.57063 -18.48928 1.000 21.04060  ? 403 HEM A CMC  1 
HETATM 6188 C  CAC  . HEM D 3 .   ? 23.95208  -12.67133 -19.03917 1.000 23.11105  ? 403 HEM A CAC  1 
HETATM 6189 C  CBC  . HEM D 3 .   ? 24.43790  -13.80119 -18.55236 1.000 42.58411  ? 403 HEM A CBC  1 
HETATM 6190 C  C1D  . HEM D 3 .   ? 22.35626  -8.97833  -20.89636 1.000 19.78352  ? 403 HEM A C1D  1 
HETATM 6191 C  C2D  . HEM D 3 .   ? 23.16455  -7.89023  -21.41549 1.000 22.04156  ? 403 HEM A C2D  1 
HETATM 6192 C  C3D  . HEM D 3 .   ? 22.34490  -6.98524  -21.99124 1.000 19.95965  ? 403 HEM A C3D  1 
HETATM 6193 C  C4D  . HEM D 3 .   ? 21.00727  -7.47635  -21.88365 1.000 18.66795  ? 403 HEM A C4D  1 
HETATM 6194 C  CMD  . HEM D 3 .   ? 24.70016  -7.80304  -21.27837 1.000 23.40397  ? 403 HEM A CMD  1 
HETATM 6195 C  CAD  . HEM D 3 .   ? 22.75010  -5.64899  -22.66759 1.000 20.99620  ? 403 HEM A CAD  1 
HETATM 6196 C  CBD  . HEM D 3 .   ? 22.91079  -5.82125  -24.17781 1.000 21.61720  ? 403 HEM A CBD  1 
HETATM 6197 C  CGD  . HEM D 3 .   ? 23.19581  -4.50309  -24.88809 1.000 22.85525  ? 403 HEM A CGD  1 
HETATM 6198 O  O1D  . HEM D 3 .   ? 22.94624  -3.42047  -24.28118 1.000 22.88754  ? 403 HEM A O1D  1 
HETATM 6199 O  O2D  . HEM D 3 .   ? 23.68235  -4.52839  -26.06927 1.000 23.46397  ? 403 HEM A O2D  1 
HETATM 6200 N  NA   . HEM D 3 .   ? 18.17747  -8.42863  -21.60192 1.000 17.81468  ? 403 HEM A NA   1 
HETATM 6201 N  NB   . HEM D 3 .   ? 17.81801  -10.92955 -20.26897 1.000 16.87636  ? 403 HEM A NB   1 
HETATM 6202 N  NC   . HEM D 3 .   ? 20.64138  -11.15293 -19.89909 1.000 17.31705  ? 403 HEM A NC   1 
HETATM 6203 N  ND   . HEM D 3 .   ? 21.02801  -8.68801  -21.19763 1.000 19.22524  ? 403 HEM A ND   1 
HETATM 6204 FE FE   . HEM D 3 .   ? 19.40337  -9.80246  -20.73055 1.000 18.87048  ? 403 HEM A FE   1 
HETATM 6205 H  HHB  . HEM D 3 .   ? 15.04596  -9.39096  -21.21093 1.000 22.05469  ? 403 HEM A HHB  1 
HETATM 6206 H  HHC  . HEM D 3 .   ? 18.80394  -13.75541 -18.93640 1.000 23.07046  ? 403 HEM A HHC  1 
HETATM 6207 H  HHD  . HEM D 3 .   ? 23.77939  -10.11916 -20.04124 1.000 23.13014  ? 403 HEM A HHD  1 
HETATM 6208 H  HMA  . HEM D 3 .   ? 14.71715  -6.03621  -22.20984 1.000 21.31030  ? 403 HEM A HMA  1 
HETATM 6209 H  HMAA . HEM D 3 .   ? 14.32543  -7.57208  -21.99120 1.000 21.31030  ? 403 HEM A HMAA 1 
HETATM 6210 H  HMAB . HEM D 3 .   ? 14.63376  -7.02687  -23.46355 1.000 21.31030  ? 403 HEM A HMAB 1 
HETATM 6211 H  HAA  . HEM D 3 .   ? 18.23680  -4.78071  -23.42080 1.000 23.30070  ? 403 HEM A HAA  1 
HETATM 6212 H  HAAA . HEM D 3 .   ? 16.74364  -4.56727  -22.93614 1.000 23.30070  ? 403 HEM A HAAA 1 
HETATM 6213 H  HBA  . HEM D 3 .   ? 16.18619  -6.08626  -24.83500 1.000 23.92079  ? 403 HEM A HBA  1 
HETATM 6214 H  HBAA . HEM D 3 .   ? 17.60377  -5.64682  -25.38935 1.000 23.92079  ? 403 HEM A HBAA 1 
HETATM 6215 H  HMB  . HEM D 3 .   ? 13.72691  -11.00309 -20.05188 1.000 25.15828  ? 403 HEM A HMB  1 
HETATM 6216 H  HMBA . HEM D 3 .   ? 13.75731  -12.57803 -19.88813 1.000 25.15828  ? 403 HEM A HMBA 1 
HETATM 6217 H  HMBB . HEM D 3 .   ? 13.89467  -11.92860 -21.32603 1.000 25.15828  ? 403 HEM A HMBB 1 
HETATM 6218 H  HAB  . HEM D 3 .   ? 16.74223  -14.47914 -18.49151 1.000 21.98113  ? 403 HEM A HAB  1 
HETATM 6219 H  HBB  . HEM D 3 .   ? 14.92146  -15.67609 -19.17950 1.000 29.15822  ? 403 HEM A HBB  1 
HETATM 6220 H  HBBA . HEM D 3 .   ? 14.49057  -14.42474 -20.21447 1.000 29.15822  ? 403 HEM A HBBA 1 
HETATM 6221 H  HMC  . HEM D 3 .   ? 20.66177  -14.66577 -17.83341 1.000 25.27248  ? 403 HEM A HMC  1 
HETATM 6222 H  HMCA . HEM D 3 .   ? 22.22356  -14.77084 -18.07412 1.000 25.27248  ? 403 HEM A HMCA 1 
HETATM 6223 H  HMCB . HEM D 3 .   ? 21.21560  -15.18612 -19.22291 1.000 25.27248  ? 403 HEM A HMCB 1 
HETATM 6224 H  HAC  . HEM D 3 .   ? 24.57965  -11.98270 -19.27056 1.000 27.75703  ? 403 HEM A HAC  1 
HETATM 6225 H  HBC  . HEM D 3 .   ? 25.39543  -13.90942 -18.44133 1.000 51.12470  ? 403 HEM A HBC  1 
HETATM 6226 H  HBCA . HEM D 3 .   ? 23.83665  -14.52153 -18.30640 1.000 51.12470  ? 403 HEM A HBCA 1 
HETATM 6227 H  HMD  . HEM D 3 .   ? 25.02597  -7.00752  -21.74889 1.000 28.10853  ? 403 HEM A HMD  1 
HETATM 6228 H  HMDA . HEM D 3 .   ? 25.10941  -8.60338  -21.66873 1.000 28.10853  ? 403 HEM A HMDA 1 
HETATM 6229 H  HMDB . HEM D 3 .   ? 24.94105  -7.74283  -20.33035 1.000 28.10853  ? 403 HEM A HMDB 1 
HETATM 6230 H  HAD  . HEM D 3 .   ? 23.59197  -5.34690  -22.29224 1.000 25.21920  ? 403 HEM A HAD  1 
HETATM 6231 H  HADA . HEM D 3 .   ? 22.06279  -4.98636  -22.49607 1.000 25.21920  ? 403 HEM A HADA 1 
HETATM 6232 H  HBD  . HEM D 3 .   ? 22.09192  -6.19732  -24.53685 1.000 25.96441  ? 403 HEM A HBD  1 
HETATM 6233 H  HBDA . HEM D 3 .   ? 23.64719  -6.43013  -24.34481 1.000 25.96441  ? 403 HEM A HBDA 1 
HETATM 6234 H  HHA  . HEM D 3 .   ? 20.03623  -5.98696  -22.85421 1.000 24.55538  ? 403 HEM A HHA  1 
HETATM 6235 O  O    . HOH E 4 .   ? -4.69075  -4.95945  -27.61715 1.000 64.32458  ? 501 HOH A O    1 
HETATM 6236 O  O    . HOH E 4 .   ? 14.66195  -10.80066 -6.53820  1.000 47.16768  ? 502 HOH A O    1 
HETATM 6237 O  O    . HOH E 4 .   ? 22.90545  -6.93197  0.60366   1.000 51.99213  ? 503 HOH A O    1 
HETATM 6238 O  O    . HOH E 4 .   ? -3.64989  6.33796   -16.01010 1.000 41.10968  ? 504 HOH A O    1 
HETATM 6239 O  O    . HOH E 4 .   ? 15.99943  -35.78502 -20.43835 1.000 56.52114  ? 505 HOH A O    1 
HETATM 6240 O  O    . HOH E 4 .   ? 10.91835  5.99484   -2.01659  1.000 66.17004  ? 506 HOH A O    1 
HETATM 6241 O  O    . HOH E 4 .   ? 23.06412  -29.91798 -29.47015 1.000 53.23737  ? 507 HOH A O    1 
HETATM 6242 O  O    . HOH E 4 .   ? 26.90240  -13.43839 -28.91024 1.000 44.29993  ? 508 HOH A O    1 
HETATM 6243 O  O    . HOH E 4 .   ? 0.61223   -35.46605 -31.20472 1.000 46.37516  ? 509 HOH A O    1 
HETATM 6244 O  O    . HOH E 4 .   ? -9.07434  0.48680   -31.37404 1.000 39.83135  ? 510 HOH A O    1 
HETATM 6245 O  O    . HOH E 4 .   ? -1.80508  -29.74537 -13.11491 1.000 43.74932  ? 511 HOH A O    1 
HETATM 6246 O  O    . HOH E 4 .   ? -3.78927  -29.07505 -26.13154 1.000 51.91293  ? 512 HOH A O    1 
HETATM 6247 O  O    . HOH E 4 .   ? 24.26822  -2.31743  4.41281   1.000 51.31402  ? 513 HOH A O    1 
HETATM 6248 O  O    . HOH E 4 .   ? 33.24884  -17.05325 -3.42718  1.000 36.72782  ? 514 HOH A O    1 
HETATM 6249 O  O    . HOH E 4 .   ? 43.09919  -13.98229 -19.65740 1.000 46.18872  ? 515 HOH A O    1 
HETATM 6250 O  O    . HOH E 4 .   ? 11.90196  -28.19224 -0.14026  1.000 39.49083  ? 516 HOH A O    1 
HETATM 6251 O  O    . HOH E 4 .   ? 23.64080  -34.44051 -15.23741 1.000 45.30691  ? 517 HOH A O    1 
HETATM 6252 O  O    . HOH E 4 .   ? 18.73833  -36.38521 -15.54192 1.000 40.95565  ? 518 HOH A O    1 
HETATM 6253 O  O    . HOH E 4 .   ? -0.17134  13.59496  -31.45181 1.000 36.46857  ? 519 HOH A O    1 
HETATM 6254 O  O    . HOH E 4 .   ? 34.54997  -9.92316  -29.84274 1.000 49.56014  ? 520 HOH A O    1 
HETATM 6255 O  O    . HOH E 4 .   ? 10.64346  -37.76182 -8.25022  1.000 38.22857  ? 521 HOH A O    1 
HETATM 6256 O  O    . HOH E 4 .   ? 6.90099   -25.21230 -0.52951  1.000 30.59390  ? 522 HOH A O    1 
HETATM 6257 O  O    . HOH E 4 .   ? 20.44189  -0.08011  -34.55093 1.000 46.99035  ? 523 HOH A O    1 
HETATM 6258 O  O    . HOH E 4 .   ? 17.12495  -11.20318 -0.98399  1.000 47.24298  ? 524 HOH A O    1 
HETATM 6259 O  O    . HOH E 4 .   ? 22.72771  -17.82321 -15.20953 1.000 25.51072  ? 525 HOH A O    1 
HETATM 6260 O  O    . HOH E 4 .   ? 32.07189  -17.62902 -21.40091 1.000 53.11933  ? 526 HOH A O    1 
HETATM 6261 O  O    . HOH E 4 .   ? 26.43976  7.80208   -30.21241 1.000 55.95490  ? 527 HOH A O    1 
HETATM 6262 O  O    . HOH E 4 .   ? -2.91079  -24.21098 -26.12523 1.000 39.99024  ? 528 HOH A O    1 
HETATM 6263 O  O    . HOH E 4 .   ? -4.16349  -9.83136  -22.52906 1.000 31.91733  ? 529 HOH A O    1 
HETATM 6264 O  O    . HOH E 4 .   ? 29.26271  -25.42062 -13.31492 1.000 32.87795  ? 530 HOH A O    1 
HETATM 6265 O  O    . HOH E 4 .   ? -1.79884  9.05436   -6.51830  1.000 61.20513  ? 531 HOH A O    1 
HETATM 6266 O  O    . HOH E 4 .   ? 35.65135  -16.28002 -26.83107 1.000 44.76803  ? 532 HOH A O    1 
HETATM 6267 O  O    . HOH E 4 .   ? 41.68745  -0.02559  -24.54508 1.000 51.30069  ? 533 HOH A O    1 
HETATM 6268 O  O    . HOH E 4 .   ? 3.17209   -6.63753  -16.44601 1.000 24.24525  ? 534 HOH A O    1 
HETATM 6269 O  O    . HOH E 4 .   ? 1.61472   -7.72932  -14.05264 1.000 27.51923  ? 535 HOH A O    1 
HETATM 6270 O  O    . HOH E 4 .   ? 25.99817  6.53211   -21.96189 1.000 46.42046  ? 536 HOH A O    1 
HETATM 6271 O  O    . HOH E 4 .   ? 14.86547  -35.00218 -24.52418 1.000 54.58004  ? 537 HOH A O    1 
HETATM 6272 O  O    . HOH E 4 .   ? 12.75454  -8.09877  -9.16500  1.000 36.49487  ? 538 HOH A O    1 
HETATM 6273 O  O    . HOH E 4 .   ? -1.01105  -17.80034 -10.28260 1.000 37.52481  ? 539 HOH A O    1 
HETATM 6274 O  O    . HOH E 4 .   ? 21.24478  2.72753   -28.39597 1.000 24.49006  ? 540 HOH A O    1 
HETATM 6275 O  O    . HOH E 4 .   ? 24.15513  8.96896   -27.98184 1.000 50.91273  ? 541 HOH A O    1 
HETATM 6276 O  O    . HOH E 4 .   ? 42.03364  -5.52821  -9.61738  1.000 54.36053  ? 542 HOH A O    1 
HETATM 6277 O  O    . HOH E 4 .   ? 18.54279  2.84474   -28.17442 1.000 23.64018  ? 543 HOH A O    1 
HETATM 6278 O  O    . HOH E 4 .   ? 1.92491   -16.24804 -12.50371 1.000 38.04242  ? 544 HOH A O    1 
HETATM 6279 O  O    . HOH E 4 .   ? -2.67628  -4.09834  -31.59274 1.000 42.41299  ? 545 HOH A O    1 
HETATM 6280 O  O    . HOH E 4 .   ? 1.00734   -9.74870  -15.82698 1.000 30.12485  ? 546 HOH A O    1 
HETATM 6281 O  O    . HOH E 4 .   ? -0.58849  -26.85127 -28.09073 1.000 30.88525  ? 547 HOH A O    1 
HETATM 6282 O  O    . HOH E 4 .   ? 16.69700  -24.45172 -1.51814  1.000 44.07762  ? 548 HOH A O    1 
HETATM 6283 O  O    . HOH E 4 .   ? 27.53703  -24.35261 -15.26349 1.000 34.51793  ? 549 HOH A O    1 
HETATM 6284 O  O    . HOH E 4 .   ? 29.09662  1.78313   0.97726   1.000 45.12324  ? 550 HOH A O    1 
HETATM 6285 O  O    . HOH E 4 .   ? 7.46422   10.32833  -20.29827 1.000 28.68282  ? 551 HOH A O    1 
HETATM 6286 O  O    . HOH E 4 .   ? -5.12454  -15.44712 -18.71548 1.000 52.91071  ? 552 HOH A O    1 
HETATM 6287 O  O    . HOH E 4 .   ? 15.29017  -38.73168 -8.96730  1.000 44.73953  ? 553 HOH A O    1 
HETATM 6288 O  O    . HOH E 4 .   ? 34.50138  -18.61141 -28.63982 1.000 44.18004  ? 554 HOH A O    1 
HETATM 6289 O  O    . HOH E 4 .   ? 4.39880   7.20537   -13.39843 1.000 28.71905  ? 555 HOH A O    1 
HETATM 6290 O  O    . HOH E 4 .   ? 4.15105   -16.68473 -5.20705  1.000 33.44380  ? 556 HOH A O    1 
HETATM 6291 O  O    . HOH E 4 .   ? 41.43457  -5.94446  -20.14833 1.000 46.27598  ? 557 HOH A O    1 
HETATM 6292 O  O    . HOH E 4 .   ? 25.37025  -16.40202 -27.01216 1.000 30.35669  ? 558 HOH A O    1 
HETATM 6293 O  O    . HOH E 4 .   ? 14.20816  -32.86197 -24.29374 1.000 51.40832  ? 559 HOH A O    1 
HETATM 6294 O  O    . HOH E 4 .   ? 39.48710  -6.81072  -22.48967 1.000 38.40990  ? 560 HOH A O    1 
HETATM 6295 O  O    . HOH E 4 .   ? -0.88300  6.74239   -29.49901 1.000 24.43075  ? 561 HOH A O    1 
HETATM 6296 O  O    . HOH E 4 .   ? -5.55937  7.57073   -29.38855 1.000 41.29262  ? 562 HOH A O    1 
HETATM 6297 O  O    . HOH E 4 .   ? 17.18172  -29.87386 -23.12336 1.000 41.34511  ? 563 HOH A O    1 
HETATM 6298 O  O    . HOH E 4 .   ? 7.43407   -37.84657 -9.69004  1.000 37.08328  ? 564 HOH A O    1 
HETATM 6299 O  O    . HOH E 4 .   ? 13.77892  -22.23620 -27.55916 1.000 28.25426  ? 565 HOH A O    1 
HETATM 6300 O  O    . HOH E 4 .   ? 20.28716  -16.93773 -16.45108 1.000 30.71055  ? 566 HOH A O    1 
HETATM 6301 O  O    . HOH E 4 .   ? 22.45424  1.38265   -33.11700 1.000 34.06556  ? 567 HOH A O    1 
HETATM 6302 O  O    . HOH E 4 .   ? 6.61319   -26.84383 -29.26359 1.000 30.07403  ? 568 HOH A O    1 
HETATM 6303 O  O    . HOH E 4 .   ? -3.27550  -19.98957 -18.84578 1.000 37.79858  ? 569 HOH A O    1 
HETATM 6304 O  O    . HOH E 4 .   ? 10.89100  19.96595  -26.37678 1.000 52.77839  ? 570 HOH A O    1 
HETATM 6305 O  O    . HOH E 4 .   ? 32.04952  -22.31808 -8.04773  1.000 41.45168  ? 571 HOH A O    1 
HETATM 6306 O  O    . HOH E 4 .   ? 17.55099  -1.55694  -23.18948 1.000 20.71915  ? 572 HOH A O    1 
HETATM 6307 O  O    . HOH E 4 .   ? 14.64776  7.87022   -36.89014 1.000 52.24751  ? 573 HOH A O    1 
HETATM 6308 O  O    . HOH E 4 .   ? 35.43875  -15.21998 -13.64420 1.000 37.17085  ? 574 HOH A O    1 
HETATM 6309 O  O    . HOH E 4 .   ? 27.88644  -6.90662  -19.84280 1.000 28.23318  ? 575 HOH A O    1 
HETATM 6310 O  O    . HOH E 4 .   ? -8.06233  -21.67832 -28.14372 1.000 52.04348  ? 576 HOH A O    1 
HETATM 6311 O  O    . HOH E 4 .   ? 14.39153  -31.76304 -26.57842 1.000 53.89488  ? 577 HOH A O    1 
HETATM 6312 O  O    . HOH E 4 .   ? 20.45084  2.35194   -15.98314 1.000 40.10603  ? 578 HOH A O    1 
HETATM 6313 O  O    . HOH E 4 .   ? 18.26590  -1.07845  -32.88278 1.000 32.43664  ? 579 HOH A O    1 
HETATM 6314 O  O    . HOH E 4 .   ? 43.42588  -11.09363 -6.16803  1.000 48.08565  ? 580 HOH A O    1 
HETATM 6315 O  O    . HOH E 4 .   ? 12.57534  -16.52164 -8.38260  1.000 32.01573  ? 581 HOH A O    1 
HETATM 6316 O  O    . HOH E 4 .   ? 25.27259  8.48806   -20.91194 1.000 45.57775  ? 582 HOH A O    1 
HETATM 6317 O  O    . HOH E 4 .   ? -3.58514  -8.81946  -8.86073  1.000 46.73742  ? 583 HOH A O    1 
HETATM 6318 O  O    . HOH E 4 .   ? 11.17115  -16.75184 -30.44514 1.000 28.71812  ? 584 HOH A O    1 
HETATM 6319 O  O    . HOH E 4 .   ? 25.52382  -33.52762 -6.99284  1.000 41.90557  ? 585 HOH A O    1 
HETATM 6320 O  O    . HOH E 4 .   ? 4.95697   -9.61959  -12.28020 1.000 21.69066  ? 586 HOH A O    1 
HETATM 6321 O  O    . HOH E 4 .   ? 37.10069  -16.79125 -7.09886  1.000 50.79665  ? 587 HOH A O    1 
HETATM 6322 O  O    . HOH E 4 .   ? 2.23198   -12.49615 -36.39017 1.000 39.76965  ? 588 HOH A O    1 
HETATM 6323 O  O    . HOH E 4 .   ? -2.94150  -29.93373 -7.88826  1.000 46.45709  ? 589 HOH A O    1 
HETATM 6324 O  O    . HOH E 4 .   ? 20.01708  -17.85244 -29.03477 1.000 37.53245  ? 590 HOH A O    1 
HETATM 6325 O  O    . HOH E 4 .   ? -5.16323  -11.39955 -18.52642 1.000 50.02995  ? 591 HOH A O    1 
HETATM 6326 O  O    . HOH E 4 .   ? -2.97310  -23.63736 -22.33444 1.000 34.65539  ? 592 HOH A O    1 
HETATM 6327 O  O    . HOH E 4 .   ? 2.50528   -9.45911  -4.32392  1.000 36.84669  ? 593 HOH A O    1 
HETATM 6328 O  O    . HOH E 4 .   ? 5.37488   1.15539   -38.67358 1.000 41.69303  ? 594 HOH A O    1 
HETATM 6329 O  O    . HOH E 4 .   ? 0.56536   -10.69145 -6.99068  1.000 29.30873  ? 595 HOH A O    1 
HETATM 6330 O  O    . HOH E 4 .   ? 22.98786  -35.70277 -9.79512  1.000 39.82696  ? 596 HOH A O    1 
HETATM 6331 O  O    . HOH E 4 .   ? -4.15626  -9.66127  -25.16013 1.000 29.14949  ? 597 HOH A O    1 
HETATM 6332 O  O    . HOH E 4 .   ? -10.94144 -20.04342 -29.73757 1.000 47.86922  ? 598 HOH A O    1 
HETATM 6333 O  O    . HOH E 4 .   ? 17.16065  -27.83117 -4.65763  1.000 26.43324  ? 599 HOH A O    1 
HETATM 6334 O  O    . HOH E 4 .   ? 18.43432  -16.85437 -10.27560 1.000 21.78642  ? 600 HOH A O    1 
HETATM 6335 O  O    . HOH E 4 .   ? 5.84983   6.66677   -9.16702  1.000 46.94173  ? 601 HOH A O    1 
HETATM 6336 O  O    . HOH E 4 .   ? 28.91505  -20.50822 -7.94244  1.000 28.24350  ? 602 HOH A O    1 
HETATM 6337 O  O    . HOH E 4 .   ? 34.52178  -12.59372 -10.16869 1.000 37.46948  ? 603 HOH A O    1 
HETATM 6338 O  O    . HOH E 4 .   ? 42.37915  1.54636   -31.12999 1.000 56.95107  ? 604 HOH A O    1 
HETATM 6339 O  O    . HOH E 4 .   ? 9.81160   -39.82340 -16.67628 1.000 40.04362  ? 605 HOH A O    1 
HETATM 6340 O  O    . HOH E 4 .   ? 14.47684  8.05529   2.92580   1.000 55.51437  ? 606 HOH A O    1 
HETATM 6341 O  O    . HOH E 4 .   ? 11.02338  -15.36184 -3.99216  1.000 40.27146  ? 607 HOH A O    1 
HETATM 6342 O  O    . HOH E 4 .   ? 20.34151  -15.01300 -0.80658  1.000 43.43862  ? 608 HOH A O    1 
HETATM 6343 O  O    . HOH E 4 .   ? 10.11371  -16.55654 -9.88096  1.000 20.54956  ? 609 HOH A O    1 
HETATM 6344 O  O    . HOH E 4 .   ? 22.90697  6.76912   4.19446   1.000 54.33571  ? 610 HOH A O    1 
HETATM 6345 O  O    . HOH E 4 .   ? 17.70811  13.28860  -32.91165 1.000 46.02195  ? 611 HOH A O    1 
HETATM 6346 O  O    . HOH E 4 .   ? 8.20452   9.42754   -34.56029 1.000 39.18839  ? 612 HOH A O    1 
HETATM 6347 O  O    . HOH E 4 .   ? 39.41651  -13.78473 -24.47523 1.000 49.73348  ? 613 HOH A O    1 
HETATM 6348 O  O    . HOH E 4 .   ? 2.68253   -18.14322 -15.19492 1.000 24.14537  ? 614 HOH A O    1 
HETATM 6349 O  O    . HOH E 4 .   ? -5.48326  -17.68112 -19.86349 1.000 58.28022  ? 615 HOH A O    1 
HETATM 6350 O  O    . HOH E 4 .   ? 11.69621  -13.77133 -30.37912 1.000 30.03365  ? 616 HOH A O    1 
HETATM 6351 O  O    . HOH E 4 .   ? 2.02347   -22.40829 -37.56938 1.000 34.39571  ? 617 HOH A O    1 
HETATM 6352 O  O    . HOH E 4 .   ? -9.12467  -4.13024  -21.03254 1.000 40.49506  ? 618 HOH A O    1 
HETATM 6353 O  O    . HOH E 4 .   ? 8.02079   -43.10201 -4.64338  1.000 47.91786  ? 619 HOH A O    1 
HETATM 6354 O  O    . HOH E 4 .   ? 9.05313   -5.69537  -3.59218  1.000 49.05987  ? 620 HOH A O    1 
HETATM 6355 O  O    . HOH E 4 .   ? 7.78973   -13.16827 -14.98265 1.000 21.26974  ? 621 HOH A O    1 
HETATM 6356 O  O    . HOH E 4 .   ? -5.45456  -8.64561  -16.51936 1.000 37.35427  ? 622 HOH A O    1 
HETATM 6357 O  O    . HOH E 4 .   ? 26.12525  -33.31014 -17.13973 1.000 42.09828  ? 623 HOH A O    1 
HETATM 6358 O  O    . HOH E 4 .   ? -5.11668  0.95410   -31.57429 1.000 36.65183  ? 624 HOH A O    1 
HETATM 6359 O  O    . HOH E 4 .   ? 34.80024  -1.84522  -3.04573  1.000 33.62325  ? 625 HOH A O    1 
HETATM 6360 O  O    . HOH E 4 .   ? 12.48020  -0.02915  -2.66577  1.000 52.41863  ? 626 HOH A O    1 
HETATM 6361 O  O    . HOH E 4 .   ? 30.99772  -24.87771 -18.07200 1.000 52.79986  ? 627 HOH A O    1 
HETATM 6362 O  O    . HOH E 4 .   ? -6.61542  -4.40307  -27.04721 1.000 34.48487  ? 628 HOH A O    1 
HETATM 6363 O  O    . HOH E 4 .   ? 19.07410  10.54887  -17.52616 1.000 39.16056  ? 629 HOH A O    1 
HETATM 6364 O  O    . HOH E 4 .   ? 7.79823   -21.37921 0.62064   1.000 46.34132  ? 630 HOH A O    1 
HETATM 6365 O  O    . HOH E 4 .   ? 3.90727   -3.46685  -2.17494  1.000 50.06338  ? 631 HOH A O    1 
HETATM 6366 O  O    . HOH E 4 .   ? 34.29308  -0.37635  -24.52843 1.000 37.09564  ? 632 HOH A O    1 
HETATM 6367 O  O    . HOH E 4 .   ? 10.03084  -18.76887 -2.46994  1.000 34.53620  ? 633 HOH A O    1 
HETATM 6368 O  O    . HOH E 4 .   ? 36.91100  2.87623   -17.77152 1.000 53.17298  ? 634 HOH A O    1 
HETATM 6369 O  O    . HOH E 4 .   ? 17.51377  0.15299   -37.24444 1.000 44.33399  ? 635 HOH A O    1 
HETATM 6370 O  O    . HOH E 4 .   ? 32.38685  -22.28269 -22.18423 1.000 47.74585  ? 636 HOH A O    1 
HETATM 6371 O  O    . HOH E 4 .   ? 21.01705  7.99052   -29.87921 1.000 41.52040  ? 637 HOH A O    1 
HETATM 6372 O  O    . HOH E 4 .   ? 39.04573  -20.05233 -12.65601 1.000 51.48998  ? 638 HOH A O    1 
HETATM 6373 O  O    . HOH E 4 .   ? 20.38380  -21.68686 -0.14429  1.000 58.11168  ? 639 HOH A O    1 
HETATM 6374 O  O    . HOH E 4 .   ? 22.42051  -25.68705 -27.32606 1.000 47.63991  ? 640 HOH A O    1 
HETATM 6375 O  O    . HOH E 4 .   ? 12.78817  -29.67567 -32.22330 1.000 41.34673  ? 641 HOH A O    1 
HETATM 6376 O  O    . HOH E 4 .   ? 23.88253  -15.77389 -24.75542 1.000 24.67433  ? 642 HOH A O    1 
HETATM 6377 O  O    . HOH E 4 .   ? 20.39333  3.07346   -12.36914 1.000 45.89051  ? 643 HOH A O    1 
HETATM 6378 O  O    . HOH E 4 .   ? 1.23063   -4.05300  -33.04310 1.000 23.91557  ? 644 HOH A O    1 
HETATM 6379 O  O    . HOH E 4 .   ? 5.20316   -4.70185  -20.16478 1.000 19.29211  ? 645 HOH A O    1 
HETATM 6380 O  O    . HOH E 4 .   ? 14.05319  -10.46359 -9.75441  1.000 31.73856  ? 646 HOH A O    1 
HETATM 6381 O  O    . HOH E 4 .   ? 36.81776  -19.40549 -11.95901 1.000 48.79611  ? 647 HOH A O    1 
HETATM 6382 O  O    . HOH E 4 .   ? 26.35141  -17.35048 0.85700   1.000 31.68841  ? 648 HOH A O    1 
HETATM 6383 O  O    . HOH E 4 .   ? 24.55314  -13.37560 -27.60767 1.000 35.82939  ? 649 HOH A O    1 
HETATM 6384 O  O    . HOH E 4 .   ? 16.66708  14.07507  -20.24318 1.000 45.30867  ? 650 HOH A O    1 
HETATM 6385 O  O    . HOH E 4 .   ? 43.69850  -17.33802 -11.09965 1.000 51.17307  ? 651 HOH A O    1 
HETATM 6386 O  O    . HOH E 4 .   ? 22.79867  10.59557  -19.52962 1.000 54.50143  ? 652 HOH A O    1 
HETATM 6387 O  O    . HOH E 4 .   ? -6.43144  -2.95525  -14.99869 1.000 39.35063  ? 653 HOH A O    1 
HETATM 6388 O  O    . HOH E 4 .   ? 28.38783  -28.16193 -13.02935 1.000 31.90290  ? 654 HOH A O    1 
HETATM 6389 O  O    . HOH E 4 .   ? 3.47075   -25.76052 -34.50008 1.000 30.87051  ? 655 HOH A O    1 
HETATM 6390 O  O    . HOH E 4 .   ? 18.31433  -31.80955 0.49575   1.000 51.20456  ? 656 HOH A O    1 
HETATM 6391 O  O    . HOH E 4 .   ? 1.53877   13.62310  -25.60217 1.000 30.59465  ? 657 HOH A O    1 
HETATM 6392 O  O    . HOH E 4 .   ? 24.92719  9.44527   -15.78535 1.000 48.14683  ? 658 HOH A O    1 
HETATM 6393 O  O    . HOH E 4 .   ? 32.12243  0.71517   -32.59935 1.000 45.13206  ? 659 HOH A O    1 
HETATM 6394 O  O    . HOH E 4 .   ? 32.47285  -10.94546 -10.15284 1.000 35.78186  ? 660 HOH A O    1 
HETATM 6395 O  O    . HOH E 4 .   ? -3.48732  8.20493   -17.85191 1.000 37.12925  ? 661 HOH A O    1 
HETATM 6396 O  O    . HOH E 4 .   ? -3.90992  -21.02302 -21.74232 1.000 35.02969  ? 662 HOH A O    1 
HETATM 6397 O  O    . HOH E 4 .   ? 33.74164  2.93958   -23.64453 1.000 48.71201  ? 663 HOH A O    1 
HETATM 6398 O  O    . HOH E 4 .   ? 29.91832  -27.96725 -19.67908 1.000 35.52854  ? 664 HOH A O    1 
HETATM 6399 O  O    . HOH E 4 .   ? 33.09868  1.75993   -26.12118 1.000 37.66092  ? 665 HOH A O    1 
HETATM 6400 O  O    . HOH E 4 .   ? 18.31019  4.67396   -15.86038 1.000 26.23789  ? 666 HOH A O    1 
HETATM 6401 O  O    . HOH E 4 .   ? 16.54803  -19.68513 -3.46002  1.000 40.22610  ? 667 HOH A O    1 
HETATM 6402 O  O    . HOH E 4 .   ? 11.62431  19.18943  -24.35261 1.000 46.79667  ? 668 HOH A O    1 
HETATM 6403 O  O    . HOH E 4 .   ? 32.49895  1.45221   -16.94438 1.000 40.73836  ? 669 HOH A O    1 
HETATM 6404 O  O    . HOH E 4 .   ? 1.25227   -36.03072 -15.13171 1.000 45.77062  ? 670 HOH A O    1 
HETATM 6405 O  O    . HOH E 4 .   ? -0.51089  -5.31810  -6.77625  1.000 38.23135  ? 671 HOH A O    1 
HETATM 6406 O  O    . HOH E 4 .   ? 17.82659  -2.26855  -29.02050 1.000 26.01008  ? 672 HOH A O    1 
HETATM 6407 O  O    . HOH E 4 .   ? 1.23302   7.81243   -9.01666  1.000 42.49542  ? 673 HOH A O    1 
HETATM 6408 O  O    . HOH E 4 .   ? 9.10937   -17.65318 -34.35096 1.000 38.25906  ? 674 HOH A O    1 
HETATM 6409 O  O    . HOH E 4 .   ? 15.81555  9.68919   -15.73893 1.000 36.09315  ? 675 HOH A O    1 
HETATM 6410 O  O    . HOH E 4 .   ? 15.92440  -35.38159 -2.03063  1.000 37.56116  ? 676 HOH A O    1 
HETATM 6411 O  O    . HOH E 4 .   ? 22.09709  -32.52668 -4.18272  1.000 34.77500  ? 677 HOH A O    1 
HETATM 6412 O  O    . HOH E 4 .   ? 0.29241   -19.14122 -36.87574 1.000 38.18891  ? 678 HOH A O    1 
HETATM 6413 O  O    . HOH E 4 .   ? 2.59467   -13.65049 -17.20727 1.000 30.15697  ? 679 HOH A O    1 
HETATM 6414 O  O    . HOH E 4 .   ? -1.88476  -33.11646 -24.75027 1.000 40.77510  ? 680 HOH A O    1 
HETATM 6415 O  O    . HOH E 4 .   ? 27.89724  -29.00299 -25.40576 1.000 49.24144  ? 681 HOH A O    1 
HETATM 6416 O  O    . HOH E 4 .   ? 15.52159  2.37255   -29.27137 1.000 23.51218  ? 682 HOH A O    1 
HETATM 6417 O  O    . HOH E 4 .   ? 8.37741   -22.91807 1.96235   1.000 39.43372  ? 683 HOH A O    1 
HETATM 6418 O  O    . HOH E 4 .   ? 27.04889  -9.63303  -29.75536 1.000 44.50511  ? 684 HOH A O    1 
HETATM 6419 O  O    . HOH E 4 .   ? 34.03170  0.21422   -9.69761  1.000 37.25804  ? 685 HOH A O    1 
HETATM 6420 O  O    . HOH E 4 .   ? 37.52957  -10.13494 -28.47767 1.000 49.33936  ? 686 HOH A O    1 
HETATM 6421 O  O    . HOH E 4 .   ? 10.93262  -9.69286  -20.74506 1.000 17.01697  ? 687 HOH A O    1 
HETATM 6422 O  O    . HOH E 4 .   ? 16.13646  -14.47153 -3.97389  1.000 36.07871  ? 688 HOH A O    1 
HETATM 6423 O  O    . HOH E 4 .   ? -1.45757  11.73531  -18.49914 1.000 44.52826  ? 689 HOH A O    1 
HETATM 6424 O  O    . HOH E 4 .   ? 2.08097   5.09198   -7.30843  1.000 47.25382  ? 690 HOH A O    1 
HETATM 6425 O  O    . HOH E 4 .   ? 17.96193  6.50565   -22.11902 1.000 24.50916  ? 691 HOH A O    1 
HETATM 6426 O  O    . HOH E 4 .   ? 15.06119  -26.54012 -26.25339 1.000 34.00450  ? 692 HOH A O    1 
HETATM 6427 O  O    . HOH E 4 .   ? 22.72736  2.98533   -30.83452 1.000 29.40664  ? 693 HOH A O    1 
HETATM 6428 O  O    . HOH E 4 .   ? 6.63196   -21.16783 -29.42255 1.000 22.32615  ? 694 HOH A O    1 
HETATM 6429 O  O    . HOH E 4 .   ? 11.15319  -4.41721  -6.08490  1.000 39.23879  ? 695 HOH A O    1 
HETATM 6430 O  O    . HOH E 4 .   ? 8.84413   3.67896   -8.04815  1.000 47.93230  ? 696 HOH A O    1 
HETATM 6431 O  O    . HOH E 4 .   ? 39.60390  -5.97603  -3.99759  1.000 48.23697  ? 697 HOH A O    1 
HETATM 6432 O  O    . HOH E 4 .   ? 7.23336   -15.87340 -12.65416 1.000 23.70741  ? 698 HOH A O    1 
HETATM 6433 O  O    . HOH E 4 .   ? -1.88484  -13.71398 -5.04166  1.000 42.97751  ? 699 HOH A O    1 
HETATM 6434 O  O    . HOH E 4 .   ? 22.89562  -23.11118 -26.76613 1.000 37.81800  ? 700 HOH A O    1 
HETATM 6435 O  O    . HOH E 4 .   ? 12.10888  -34.53318 -20.70463 1.000 36.60647  ? 701 HOH A O    1 
HETATM 6436 O  O    . HOH E 4 .   ? -2.59210  -7.47116  -22.49733 1.000 22.29262  ? 702 HOH A O    1 
HETATM 6437 O  O    . HOH E 4 .   ? 41.24000  -3.05293  -10.17023 1.000 45.68077  ? 703 HOH A O    1 
HETATM 6438 O  O    . HOH E 4 .   ? 4.06506   -34.61933 -0.99983  1.000 45.43538  ? 704 HOH A O    1 
HETATM 6439 O  O    . HOH E 4 .   ? 36.92615  -0.15859  -23.68911 1.000 46.55851  ? 705 HOH A O    1 
HETATM 6440 O  O    . HOH E 4 .   ? 11.11319  -26.22592 -15.63059 1.000 25.55230  ? 706 HOH A O    1 
HETATM 6441 O  O    . HOH E 4 .   ? 26.59828  -20.88545 2.96090   1.000 46.19781  ? 707 HOH A O    1 
HETATM 6442 O  O    . HOH E 4 .   ? 24.83326  -33.80090 -10.94629 1.000 35.84334  ? 708 HOH A O    1 
HETATM 6443 O  O    . HOH E 4 .   ? 24.04792  -4.46070  1.19787   1.000 39.57526  ? 709 HOH A O    1 
HETATM 6444 O  O    . HOH E 4 .   ? -0.01010  0.76672   -8.69314  1.000 47.46807  ? 710 HOH A O    1 
HETATM 6445 O  O    . HOH E 4 .   ? 26.59202  5.44188   -19.94055 1.000 45.47894  ? 711 HOH A O    1 
HETATM 6446 O  O    . HOH E 4 .   ? 15.85919  3.65080   -6.57667  1.000 48.48647  ? 712 HOH A O    1 
HETATM 6447 O  O    . HOH E 4 .   ? 8.28710   0.04676   -7.31488  1.000 43.32836  ? 713 HOH A O    1 
HETATM 6448 O  O    . HOH E 4 .   ? 9.71335   -27.06274 -30.72018 1.000 29.69128  ? 714 HOH A O    1 
HETATM 6449 O  O    . HOH E 4 .   ? 28.92444  -16.55188 -31.76509 1.000 44.15792  ? 715 HOH A O    1 
HETATM 6450 O  O    . HOH E 4 .   ? 17.35889  -8.05757  -32.98545 1.000 36.81864  ? 716 HOH A O    1 
HETATM 6451 O  O    . HOH E 4 .   ? -3.86862  -2.21915  -31.50087 1.000 46.49957  ? 717 HOH A O    1 
HETATM 6452 O  O    . HOH E 4 .   ? 20.39357  -21.89340 -26.22610 1.000 28.50860  ? 718 HOH A O    1 
HETATM 6453 O  O    . HOH E 4 .   ? 24.49404  -4.84908  -31.25587 1.000 50.72684  ? 719 HOH A O    1 
HETATM 6454 O  O    . HOH E 4 .   ? 33.06539  -8.95443  -1.15262  1.000 33.78433  ? 720 HOH A O    1 
HETATM 6455 O  O    . HOH E 4 .   ? -0.78328  1.76125   -10.77428 1.000 33.87516  ? 721 HOH A O    1 
HETATM 6456 O  O    . HOH E 4 .   ? 13.02671  -11.05668 -27.90349 1.000 20.13481  ? 722 HOH A O    1 
HETATM 6457 O  O    . HOH E 4 .   ? 22.47853  -21.58078 -6.40838  1.000 28.06802  ? 723 HOH A O    1 
HETATM 6458 O  O    . HOH E 4 .   ? 22.13185  10.19142  -17.26911 1.000 41.44515  ? 724 HOH A O    1 
HETATM 6459 O  O    . HOH E 4 .   ? 28.94189  -29.42209 -22.72454 1.000 35.96772  ? 725 HOH A O    1 
HETATM 6460 O  O    . HOH E 4 .   ? 23.40099  -34.74594 -5.59950  1.000 38.98794  ? 726 HOH A O    1 
HETATM 6461 O  O    . HOH E 4 .   ? 40.32962  0.98957   -11.97375 1.000 48.05708  ? 727 HOH A O    1 
HETATM 6462 O  O    . HOH E 4 .   ? 4.85095   -11.57715 -14.22886 1.000 24.05196  ? 728 HOH A O    1 
HETATM 6463 O  O    . HOH E 4 .   ? 29.09456  -26.21808 -8.88391  1.000 38.33114  ? 729 HOH A O    1 
HETATM 6464 O  O    . HOH E 4 .   ? 25.20498  -20.41902 -0.93231  1.000 30.39852  ? 730 HOH A O    1 
HETATM 6465 O  O    . HOH E 4 .   ? -6.55724  -14.48056 -25.91671 1.000 28.63760  ? 731 HOH A O    1 
HETATM 6466 O  O    . HOH E 4 .   ? 17.77131  -1.74558  -2.72147  1.000 43.60832  ? 732 HOH A O    1 
HETATM 6467 O  O    . HOH E 4 .   ? 13.14568  18.64596  -31.10843 1.000 42.02807  ? 733 HOH A O    1 
HETATM 6468 O  O    . HOH E 4 .   ? 17.61770  -15.87906 -12.83336 1.000 18.62843  ? 734 HOH A O    1 
HETATM 6469 O  O    . HOH E 4 .   ? 29.70251  1.73124   -3.24034  1.000 44.30117  ? 735 HOH A O    1 
HETATM 6470 O  O    . HOH E 4 .   ? 38.86611  -17.70360 -7.76855  1.000 61.17410  ? 736 HOH A O    1 
HETATM 6471 O  O    . HOH E 4 .   ? -0.18901  -15.39957 -34.35940 1.000 37.53653  ? 737 HOH A O    1 
HETATM 6472 O  O    . HOH E 4 .   ? 20.17430  -7.91379  -32.60032 1.000 46.96423  ? 738 HOH A O    1 
HETATM 6473 O  O    . HOH E 4 .   ? 42.16625  -0.66074  -16.16477 1.000 45.33554  ? 739 HOH A O    1 
HETATM 6474 O  O    . HOH E 4 .   ? -1.91443  -9.11383  -15.68649 1.000 28.27662  ? 740 HOH A O    1 
HETATM 6475 O  O    . HOH E 4 .   ? -11.41067 -0.38956  -25.54153 1.000 41.04802  ? 741 HOH A O    1 
HETATM 6476 O  O    . HOH E 4 .   ? 22.30928  -14.29445 -29.79833 1.000 40.59715  ? 742 HOH A O    1 
HETATM 6477 O  O    . HOH E 4 .   ? 25.94559  -27.04910 -6.58532  1.000 40.09211  ? 743 HOH A O    1 
HETATM 6478 O  O    . HOH E 4 .   ? -2.67824  -18.72671 -15.54147 1.000 53.51778  ? 744 HOH A O    1 
HETATM 6479 O  O    . HOH E 4 .   ? 25.99944  0.41906   -35.38987 1.000 49.43210  ? 745 HOH A O    1 
HETATM 6480 O  O    . HOH E 4 .   ? -12.79688 3.12320   -23.06456 1.000 42.82958  ? 746 HOH A O    1 
HETATM 6481 O  O    . HOH E 4 .   ? -6.70077  -12.97500 -31.00170 1.000 37.51252  ? 747 HOH A O    1 
HETATM 6482 O  O    . HOH E 4 .   ? 21.47927  4.99297   -11.92637 1.000 45.44730  ? 748 HOH A O    1 
HETATM 6483 O  O    . HOH E 4 .   ? 4.20830   -5.62981  -36.10109 1.000 44.36204  ? 749 HOH A O    1 
HETATM 6484 O  O    . HOH E 4 .   ? -5.19533  -28.50073 -16.57809 1.000 41.71934  ? 750 HOH A O    1 
HETATM 6485 O  O    . HOH E 4 .   ? 12.90007  2.57371   -11.54664 1.000 30.96383  ? 751 HOH A O    1 
HETATM 6486 O  O    . HOH E 4 .   ? 14.06673  -13.54524 -29.17705 1.000 30.85422  ? 752 HOH A O    1 
HETATM 6487 O  O    . HOH E 4 .   ? -0.22492  -15.54275 -15.97470 1.000 34.31943  ? 753 HOH A O    1 
HETATM 6488 O  O    . HOH E 4 .   ? 37.18007  -2.53970  -1.59555  1.000 43.25215  ? 754 HOH A O    1 
HETATM 6489 O  O    . HOH E 4 .   ? -1.21031  -28.57173 -11.06780 1.000 32.42349  ? 755 HOH A O    1 
HETATM 6490 O  O    . HOH E 4 .   ? 5.08001   -14.10847 -33.91166 1.000 28.87615  ? 756 HOH A O    1 
HETATM 6491 O  O    . HOH E 4 .   ? 8.99609   -42.28888 -8.45257  1.000 47.22304  ? 757 HOH A O    1 
HETATM 6492 O  O    . HOH E 4 .   ? 16.11866  3.77022   -38.44877 1.000 53.15806  ? 758 HOH A O    1 
HETATM 6493 O  O    . HOH E 4 .   ? 33.52413  -11.96219 -29.91494 1.000 45.02846  ? 759 HOH A O    1 
HETATM 6494 O  O    . HOH E 4 .   ? -8.48470  2.15040   -13.52410 1.000 57.49259  ? 760 HOH A O    1 
HETATM 6495 O  O    . HOH E 4 .   ? 26.58281  6.48882   -25.72181 1.000 36.20204  ? 761 HOH A O    1 
HETATM 6496 O  O    . HOH E 4 .   ? 10.80622  11.38658  -18.38774 1.000 36.53678  ? 762 HOH A O    1 
HETATM 6497 O  O    . HOH E 4 .   ? 33.26613  0.34914   -12.10717 1.000 40.43014  ? 763 HOH A O    1 
HETATM 6498 O  O    . HOH E 4 .   ? 39.87033  1.10055   -14.73108 1.000 43.18662  ? 764 HOH A O    1 
HETATM 6499 O  O    . HOH E 4 .   ? 19.73073  15.27929  -30.00798 1.000 56.63088  ? 765 HOH A O    1 
HETATM 6500 O  O    . HOH E 4 .   ? 8.93468   7.32780   -35.90234 1.000 47.33104  ? 766 HOH A O    1 
HETATM 6501 O  O    . HOH E 4 .   ? 30.94992  -19.35327 -31.67873 1.000 40.01590  ? 767 HOH A O    1 
HETATM 6502 O  O    . HOH E 4 .   ? -5.81716  -24.79771 -13.83575 1.000 61.63178  ? 768 HOH A O    1 
HETATM 6503 O  O    . HOH E 4 .   ? 4.56581   -38.63605 -29.39053 1.000 59.38781  ? 769 HOH A O    1 
HETATM 6504 O  O    . HOH E 4 .   ? 21.80316  -32.79121 -21.47976 1.000 51.28928  ? 770 HOH A O    1 
HETATM 6505 O  O    . HOH E 4 .   ? 15.03667  -26.74816 0.69309   1.000 49.18131  ? 771 HOH A O    1 
HETATM 6506 O  O    . HOH E 4 .   ? 36.39650  -16.48321 0.04202   1.000 53.37898  ? 772 HOH A O    1 
HETATM 6507 O  O    . HOH E 4 .   ? 21.00115  10.70822  -25.70105 1.000 45.35794  ? 773 HOH A O    1 
HETATM 6508 O  O    . HOH E 4 .   ? 31.51353  -22.29966 -15.17601 1.000 46.02746  ? 774 HOH A O    1 
HETATM 6509 O  O    . HOH E 4 .   ? -1.41464  -12.34073 -7.54091  1.000 40.72836  ? 775 HOH A O    1 
HETATM 6510 O  O    . HOH E 4 .   ? -3.31810  -11.55983 -15.89055 1.000 45.39657  ? 776 HOH A O    1 
HETATM 6511 O  O    . HOH E 4 .   ? -5.02401  -26.01347 -29.48399 1.000 34.76905  ? 777 HOH A O    1 
HETATM 6512 O  O    . HOH E 4 .   ? 30.39856  3.47355   -20.47720 1.000 55.44004  ? 778 HOH A O    1 
HETATM 6513 O  O    . HOH E 4 .   ? 12.79364  -6.61855  -6.88452  1.000 37.15490  ? 779 HOH A O    1 
HETATM 6514 O  O    . HOH E 4 .   ? 10.58914  -13.47347 -6.72442  1.000 38.59018  ? 780 HOH A O    1 
HETATM 6515 O  O    . HOH E 4 .   ? 17.97381  5.62073   -35.67537 1.000 34.71750  ? 781 HOH A O    1 
HETATM 6516 O  O    . HOH E 4 .   ? 6.74624   -10.31510 -35.89818 1.000 36.14815  ? 782 HOH A O    1 
HETATM 6517 O  O    . HOH E 4 .   ? 37.41378  0.60951   -6.43449  1.000 45.26165  ? 783 HOH A O    1 
HETATM 6518 O  O    . HOH E 4 .   ? 24.56045  -21.17140 1.61830   1.000 47.75666  ? 784 HOH A O    1 
HETATM 6519 O  O    . HOH E 4 .   ? -4.28168  -27.58314 -13.40757 1.000 51.06362  ? 785 HOH A O    1 
HETATM 6520 O  O    . HOH E 4 .   ? 21.64619  -19.45843 -4.42661  1.000 34.59652  ? 786 HOH A O    1 
HETATM 6521 O  O    . HOH E 4 .   ? 28.64577  6.47781   -28.96641 1.000 45.75606  ? 787 HOH A O    1 
HETATM 6522 O  O    . HOH E 4 .   ? 1.22262   -5.68570  -4.89143  1.000 46.24636  ? 788 HOH A O    1 
HETATM 6523 O  O    . HOH E 4 .   ? 15.69284  -34.34393 0.41784   1.000 47.55771  ? 789 HOH A O    1 
HETATM 6524 O  O    . HOH E 4 .   ? 17.94177  14.03370  -24.98344 1.000 49.59107  ? 790 HOH A O    1 
HETATM 6525 O  O    . HOH E 4 .   ? 0.55858   -23.95458 -5.12157  1.000 40.81635  ? 791 HOH A O    1 
HETATM 6526 O  O    . HOH E 4 .   ? 6.84677   -23.96244 -32.05282 1.000 41.74211  ? 792 HOH A O    1 
HETATM 6527 O  O    . HOH E 4 .   ? -5.94815  3.38816   -30.79206 1.000 37.23434  ? 793 HOH A O    1 
HETATM 6528 O  O    . HOH E 4 .   ? 14.96158  -39.41142 -11.54772 1.000 46.28776  ? 794 HOH A O    1 
HETATM 6529 O  O    . HOH E 4 .   ? 17.70893  0.45258   -29.80569 1.000 28.56616  ? 795 HOH A O    1 
HETATM 6530 O  O    . HOH E 4 .   ? 43.64512  -5.77265  -11.70396 1.000 58.45862  ? 796 HOH A O    1 
HETATM 6531 O  O    . HOH E 4 .   ? -2.25187  -37.64725 -7.64058  1.000 59.18867  ? 797 HOH A O    1 
HETATM 6532 O  O    . HOH E 4 .   ? 26.73656  -29.34389 -8.27723  1.000 44.68569  ? 798 HOH A O    1 
HETATM 6533 O  O    . HOH E 4 .   ? -5.29672  8.46172   -14.65500 1.000 46.38121  ? 799 HOH A O    1 
HETATM 6534 O  O    . HOH E 4 .   ? 46.21889  -16.27114 -9.49977  1.000 55.11839  ? 800 HOH A O    1 
HETATM 6535 O  O    . HOH E 4 .   ? 16.34403  -14.91347 -31.00567 1.000 48.82925  ? 801 HOH A O    1 
HETATM 6536 O  O    . HOH E 4 .   ? 0.22089   -12.41947 -14.50360 1.000 52.34004  ? 802 HOH A O    1 
HETATM 6537 O  O    . HOH E 4 .   ? 0.79055   1.28706   -32.87571 1.000 19.83218  ? 803 HOH A O    1 
HETATM 6538 O  O    . HOH E 4 .   ? -7.20768  -18.65026 -23.47363 1.000 53.80087  ? 804 HOH A O    1 
HETATM 6539 O  O    . HOH E 4 .   ? 18.41579  -23.81206 -25.81592 1.000 29.39055  ? 805 HOH A O    1 
HETATM 6540 O  O    . HOH E 4 .   ? -0.63227  -38.41774 -6.53642  1.000 55.84424  ? 806 HOH A O    1 
HETATM 6541 O  O    . HOH E 4 .   ? 35.71160  -14.60498 -1.08784  1.000 64.13846  ? 807 HOH A O    1 
HETATM 6542 O  O    . HOH E 4 .   ? 33.40772  -1.74887  -32.84286 1.000 49.65948  ? 808 HOH A O    1 
HETATM 6543 O  O    . HOH E 4 .   ? -0.98799  -17.72452 -13.63600 1.000 48.76338  ? 809 HOH A O    1 
HETATM 6544 O  O    . HOH E 4 .   ? 18.84662  -35.19331 -21.34165 1.000 58.86716  ? 810 HOH A O    1 
HETATM 6545 O  O    . HOH E 4 .   ? 23.17380  -21.71499 -2.39309  1.000 42.61749  ? 811 HOH A O    1 
HETATM 6546 O  O    . HOH E 4 .   ? -7.07068  0.03609   -32.37777 1.000 47.42385  ? 812 HOH A O    1 
HETATM 6547 O  O    . HOH E 4 .   ? 19.32494  -28.40355 -24.72467 1.000 54.39607  ? 813 HOH A O    1 
HETATM 6548 O  O    . HOH E 4 .   ? 14.52516  -11.04053 -1.74705  1.000 55.16926  ? 814 HOH A O    1 
HETATM 6549 O  O    . HOH E 4 .   ? 21.57514  -28.63295 -30.72201 1.000 53.39704  ? 815 HOH A O    1 
HETATM 6550 O  O    . HOH E 4 .   ? 4.42268   -28.11672 -33.09756 1.000 32.77665  ? 816 HOH A O    1 
HETATM 6551 O  O    . HOH E 4 .   ? 28.87746  -6.03161  -31.20450 1.000 54.49213  ? 817 HOH A O    1 
HETATM 6552 O  O    . HOH E 4 .   ? -3.22297  -26.85861 -27.72530 1.000 44.83611  ? 818 HOH A O    1 
HETATM 6553 O  O    . HOH E 4 .   ? 22.82298  -23.96189 -5.21446  1.000 44.58098  ? 819 HOH A O    1 
HETATM 6554 O  O    . HOH E 4 .   ? 11.09120  -23.00612 -31.47605 1.000 43.80052  ? 820 HOH A O    1 
HETATM 6555 O  O    . HOH E 4 .   ? 17.33698  10.67353  -13.52667 1.000 45.99707  ? 821 HOH A O    1 
HETATM 6556 O  O    . HOH E 4 .   ? 2.02036   -5.30871  -35.46524 1.000 48.10493  ? 822 HOH A O    1 
HETATM 6557 O  O    . HOH E 4 .   ? 19.50446  -19.85936 -3.99092  1.000 49.04320  ? 823 HOH A O    1 
HETATM 6558 O  O    . HOH E 4 .   ? 34.46871  -23.27844 -23.78311 1.000 53.05840  ? 824 HOH A O    1 
HETATM 6559 O  O    . HOH E 4 .   ? 17.39789  11.56802  -34.60733 1.000 53.46006  ? 825 HOH A O    1 
HETATM 6560 O  O    . HOH E 4 .   ? -6.62548  -10.16721 -25.91474 1.000 47.96000  ? 826 HOH A O    1 
HETATM 6561 O  O    . HOH E 4 .   ? -2.72577  -12.49821 -35.47653 1.000 54.48933  ? 827 HOH A O    1 
HETATM 6562 O  O    . HOH E 4 .   ? 17.78344  16.45075  -32.77093 1.000 60.22217  ? 828 HOH A O    1 
HETATM 6563 O  O    . HOH E 4 .   ? 18.54458  -22.98071 -2.57168  1.000 55.81798  ? 829 HOH A O    1 
HETATM 6564 O  O    . HOH E 4 .   ? 20.76571  -4.57607  -34.64526 1.000 56.74184  ? 830 HOH A O    1 
HETATM 6565 O  O    . HOH E 4 .   ? 37.50672  -12.74483 -4.42756  1.000 53.87013  ? 831 HOH A O    1 
HETATM 6566 O  O    . HOH E 4 .   ? 16.44724  -27.77417 -1.95543  1.000 49.66644  ? 832 HOH A O    1 
HETATM 6567 O  O    . HOH E 4 .   ? 39.38883  1.20534   -7.61035  1.000 58.24892  ? 833 HOH A O    1 
HETATM 6568 O  O    . HOH E 4 .   ? 30.15900  -31.12303 -16.32239 1.000 41.75881  ? 834 HOH A O    1 
HETATM 6569 O  O    . HOH E 4 .   ? 27.69215  4.03517   -35.33562 1.000 53.52239  ? 835 HOH A O    1 
HETATM 6570 O  O    . HOH E 4 .   ? 8.86880   -21.13954 -31.29824 1.000 33.70917  ? 836 HOH A O    1 
HETATM 6571 O  O    . HOH E 4 .   ? 3.68655   -15.68501 -15.64659 1.000 28.11159  ? 837 HOH A O    1 
HETATM 6572 O  O    . HOH E 4 .   ? -0.89203  12.66151  -25.55445 1.000 48.88080  ? 838 HOH A O    1 
HETATM 6573 O  O    . HOH E 4 .   ? 15.21993  -19.47906 -30.63255 1.000 48.23454  ? 839 HOH A O    1 
HETATM 6574 O  O    . HOH E 4 .   ? -8.18134  -1.78777  -17.09812 1.000 45.55732  ? 840 HOH A O    1 
HETATM 6575 O  O    . HOH E 4 .   ? 2.25869   -12.01188 -15.16493 1.000 34.91793  ? 841 HOH A O    1 
HETATM 6576 O  O    . HOH E 4 .   ? 29.07783  -8.33699  -30.48613 1.000 45.45311  ? 842 HOH A O    1 
HETATM 6577 O  O    . HOH E 4 .   ? 22.32464  5.56214   -32.13167 1.000 42.28665  ? 843 HOH A O    1 
HETATM 6578 O  O    . HOH E 4 .   ? 23.33188  -26.72463 -5.98508  1.000 44.75139  ? 844 HOH A O    1 
HETATM 6579 O  O    . HOH E 4 .   ? 13.84205  -36.06524 -21.99242 1.000 48.25966  ? 845 HOH A O    1 
HETATM 6580 O  O    . HOH E 4 .   ? 21.79720  -2.43032  -35.39986 1.000 51.89073  ? 846 HOH A O    1 
HETATM 6581 O  O    . HOH E 4 .   ? 9.87039   -36.21638 -20.26881 1.000 47.94063  ? 847 HOH A O    1 
HETATM 6582 O  O    . HOH E 4 .   ? 15.77502  -17.41742 -31.65090 1.000 49.85766  ? 848 HOH A O    1 
HETATM 6583 O  O    . HOH E 4 .   ? 40.09339  -13.84111 -5.99192  1.000 55.95810  ? 849 HOH A O    1 
HETATM 6584 O  O    . HOH E 4 .   ? 16.40102  18.00693  -23.76796 1.000 57.59408  ? 850 HOH A O    1 
HETATM 6585 O  O    . HOH E 4 .   ? 25.86630  -11.09571 -31.24801 1.000 58.85059  ? 851 HOH A O    1 
HETATM 6586 O  O    . HOH E 4 .   ? 32.73033  2.42934   -14.03172 1.000 47.24187  ? 852 HOH A O    1 
HETATM 6587 O  O    . HOH E 4 .   ? -9.93381  -2.80286  -24.05661 1.000 38.92121  ? 853 HOH A O    1 
HETATM 6588 O  O    . HOH E 4 .   ? 10.29066  -19.21990 -32.20027 1.000 39.54197  ? 854 HOH A O    1 
HETATM 6589 O  O    . HOH E 4 .   ? 16.89174  -2.96668  -0.84582  1.000 57.45872  ? 855 HOH A O    1 
HETATM 6590 O  O    . HOH E 4 .   ? 16.02302  -23.60738 -27.49573 1.000 42.68171  ? 856 HOH A O    1 
HETATM 6591 O  O    . HOH E 4 .   ? 30.47260  -9.74504  -32.43915 1.000 53.50903  ? 857 HOH A O    1 
HETATM 6592 O  O    . HOH E 4 .   ? 10.64474  -25.11165 -32.63236 1.000 47.87784  ? 858 HOH A O    1 
HETATM 6593 O  O    . HOH E 4 .   ? 19.24677  -26.32351 -26.07765 1.000 44.37376  ? 859 HOH A O    1 
HETATM 6594 O  O    . HOH E 4 .   ? -9.60599  -4.18086  -25.93230 1.000 40.35266  ? 860 HOH A O    1 
HETATM 6595 O  O    . HOH E 4 .   ? 21.04030  5.21946   5.86758   1.000 60.99523  ? 861 HOH A O    1 
HETATM 6596 O  O    . HOH E 4 .   ? 5.32114   -12.75791 -36.13998 1.000 39.10413  ? 862 HOH A O    1 
HETATM 6597 O  O    . HOH E 4 .   ? 19.70127  1.38025   -36.68717 1.000 52.06562  ? 863 HOH A O    1 
HETATM 6598 O  O    . HOH E 4 .   ? 7.77727   11.66058  -18.20391 1.000 44.66264  ? 864 HOH A O    1 
HETATM 6599 O  O    . HOH E 4 .   ? -7.91115  -11.23852 -24.03035 1.000 60.49926  ? 865 HOH A O    1 
HETATM 6600 O  O    . HOH E 4 .   ? 13.58222  -22.23758 -30.65639 1.000 39.90342  ? 866 HOH A O    1 
HETATM 6601 O  O    . HOH E 4 .   ? 17.51740  -2.07665  -35.26807 1.000 43.28696  ? 867 HOH A O    1 
HETATM 6602 O  O    . HOH E 4 .   ? 3.25031   1.83863   -38.69828 1.000 46.39901  ? 868 HOH A O    1 
HETATM 6603 O  O    . HOH E 4 .   ? 9.08209   8.32999   -13.77607 1.000 48.00283  ? 869 HOH A O    1 
HETATM 6604 O  O    . HOH E 4 .   ? 34.10163  2.30916   -32.21548 1.000 51.37151  ? 870 HOH A O    1 
HETATM 6605 O  O    . HOH E 4 .   ? 15.67784  -29.70174 -26.99946 1.000 56.68872  ? 871 HOH A O    1 
HETATM 6606 O  O    . HOH E 4 .   ? 40.36369  -3.92007  -4.53926  1.000 62.68323  ? 872 HOH A O    1 
HETATM 6607 O  O    . HOH E 4 .   ? -8.02405  -16.88007 -24.82074 1.000 47.99655  ? 873 HOH A O    1 
HETATM 6608 O  O    . HOH E 4 .   ? 12.80352  -17.65968 -3.06568  1.000 47.58535  ? 874 HOH A O    1 
HETATM 6609 O  O    . HOH E 4 .   ? 21.09452  -38.09449 -16.18779 1.000 58.40358  ? 875 HOH A O    1 
HETATM 6610 O  O    . HOH E 4 .   ? 31.57161  -25.05703 -14.50032 1.000 50.65055  ? 876 HOH A O    1 
HETATM 6611 O  O    . HOH E 4 .   ? -1.38613  15.94962  -32.71657 1.000 38.97739  ? 877 HOH A O    1 
HETATM 6612 O  O    . HOH E 4 .   ? 32.70805  -11.91224 -0.38761  1.000 52.11596  ? 878 HOH A O    1 
HETATM 6613 O  O    . HOH E 4 .   ? 34.01965  0.64140   -2.68257  1.000 47.79212  ? 879 HOH A O    1 
HETATM 6614 O  O    . HOH E 4 .   ? 6.54201   -26.80331 -31.75649 1.000 38.14480  ? 880 HOH A O    1 
HETATM 6615 O  O    . HOH E 4 .   ? 5.56565   -14.16295 -14.11199 1.000 33.55072  ? 881 HOH A O    1 
HETATM 6616 O  O    . HOH E 4 .   ? 14.93041  -17.74183 -3.37401  1.000 46.47106  ? 882 HOH A O    1 
HETATM 6617 O  O    . HOH E 4 .   ? 23.30150  -30.46075 -3.28516  1.000 48.29994  ? 883 HOH A O    1 
HETATM 6618 O  O    . HOH E 4 .   ? -6.58651  -21.04431 -22.29624 1.000 51.70804  ? 884 HOH A O    1 
HETATM 6619 O  O    . HOH E 4 .   ? 28.01008  1.82246   -35.03333 1.000 43.86411  ? 885 HOH A O    1 
HETATM 6620 O  O    . HOH E 4 .   ? 22.65663  3.07607   -35.15136 1.000 49.17260  ? 886 HOH A O    1 
HETATM 6621 O  O    . HOH E 4 .   ? 5.65657   -41.36921 -11.09204 1.000 55.80843  ? 887 HOH A O    1 
HETATM 6622 O  O    . HOH E 4 .   ? -0.11748  -23.09374 -2.60928  1.000 40.32003  ? 888 HOH A O    1 
HETATM 6623 O  O    . HOH E 4 .   ? 25.20270  -35.15571 -13.30960 1.000 47.16672  ? 889 HOH A O    1 
HETATM 6624 O  O    . HOH E 4 .   ? -8.54035  -2.45354  -31.11962 1.000 43.25728  ? 890 HOH A O    1 
HETATM 6625 O  O    . HOH E 4 .   ? 32.66541  -23.45172 -16.21098 1.000 80.86396  ? 891 HOH A O    1 
HETATM 6626 O  O    . HOH E 4 .   ? 17.62736  -7.27005  -35.54722 1.000 53.42604  ? 892 HOH A O    1 
HETATM 6627 O  O    . HOH E 4 .   ? 11.91836  -32.67709 -22.96258 1.000 45.90738  ? 893 HOH A O    1 
HETATM 6628 O  O    . HOH E 4 .   ? 22.04608  -28.17880 -3.86975  1.000 43.94757  ? 894 HOH A O    1 
HETATM 6629 O  O    . HOH E 4 .   ? 35.68266  -14.19388 -29.22184 1.000 50.93692  ? 895 HOH A O    1 
HETATM 6630 O  O    . HOH E 4 .   ? 30.22774  -29.84873 -14.15384 1.000 41.36168  ? 896 HOH A O    1 
HETATM 6631 O  O    . HOH E 4 .   ? 22.03404  11.63916  -27.71239 1.000 55.22077  ? 897 HOH A O    1 
HETATM 6632 O  O    . HOH E 4 .   ? 6.59170   8.83920   -13.50918 1.000 36.53114  ? 898 HOH A O    1 
HETATM 6633 O  O    . HOH E 4 .   ? 31.50750  -26.42663 -7.72262  1.000 55.09800  ? 899 HOH A O    1 
HETATM 6634 O  O    . HOH E 4 .   ? 19.52336  -20.48707 -28.33372 1.000 42.54150  ? 900 HOH A O    1 
HETATM 6635 O  O    . HOH E 4 .   ? 5.65620   -38.56804 -31.90444 1.000 59.12405  ? 901 HOH A O    1 
HETATM 6636 O  O    . HOH E 4 .   ? 25.53971  -34.28886 -19.51128 1.000 48.21286  ? 902 HOH A O    1 
HETATM 6637 O  O    . HOH E 4 .   ? 0.03641   -10.06926 -4.47643  1.000 46.14764  ? 903 HOH A O    1 
HETATM 6638 O  O    . HOH E 4 .   ? 17.70113  2.69650   -40.11843 1.000 61.52213  ? 904 HOH A O    1 
HETATM 6639 O  O    . HOH E 4 .   ? 0.23162   -16.24396 -36.79689 1.000 48.96953  ? 905 HOH A O    1 
HETATM 6640 O  O    . HOH E 4 .   ? 18.18743  -4.65996  -35.95940 1.000 55.34288  ? 906 HOH A O    1 
HETATM 6641 O  O    . HOH E 4 .   ? 22.82107  -2.79565  6.26562   1.000 53.93010  ? 907 HOH A O    1 
HETATM 6642 O  O    . HOH E 4 .   ? 34.28515  3.90224   -27.66115 1.000 44.61349  ? 908 HOH A O    1 
HETATM 6643 O  O    . HOH E 4 .   ? 28.45668  -28.61721 -10.41823 1.000 41.51000  ? 909 HOH A O    1 
HETATM 6644 O  O    . HOH E 4 .   ? 26.44037  9.62394   -18.99480 1.000 53.12898  ? 910 HOH A O    1 
HETATM 6645 O  O    . HOH E 4 .   ? 2.15663   -7.20295  -2.75318  1.000 48.63270  ? 911 HOH A O    1 
HETATM 6646 O  O    . HOH E 4 .   ? 19.45485  -27.28474 -3.20681  1.000 38.56753  ? 912 HOH A O    1 
HETATM 6647 O  O    . HOH E 4 .   ? -2.65661  -13.71941 -37.07211 1.000 52.74826  ? 913 HOH A O    1 
HETATM 6648 O  O    . HOH E 4 .   ? 19.80192  12.58714  -24.64115 1.000 54.33790  ? 914 HOH A O    1 
HETATM 6649 O  O    . HOH E 4 .   ? 38.55845  -13.58139 -27.09347 1.000 50.67910  ? 915 HOH A O    1 
HETATM 6650 O  O    . HOH E 4 .   ? 20.27749  -24.57127 -3.61716  1.000 44.56418  ? 916 HOH A O    1 
HETATM 6651 O  O    . HOH E 4 .   ? -6.05565  -15.75446 -35.42943 1.000 54.92909  ? 917 HOH A O    1 
HETATM 6652 O  O    . HOH E 4 .   ? -7.24054  -27.60204 -29.09525 1.000 45.60131  ? 918 HOH A O    1 
HETATM 6653 O  O    . HOH E 4 .   ? 25.91898  -30.28047 -3.51248  1.000 54.19345  ? 919 HOH A O    1 
HETATM 6654 O  O    . HOH E 4 .   ? 40.02308  -12.38211 -2.76326  1.000 55.17430  ? 920 HOH A O    1 
HETATM 6655 O  O    . HOH E 4 .   ? 40.33989  3.25566   -6.51614  1.000 61.82998  ? 921 HOH A O    1 
HETATM 6656 O  O    . HOH E 4 .   ? 14.18257  -10.74616 -35.25540 1.000 57.05851  ? 922 HOH A O    1 
HETATM 6657 O  O    . HOH E 4 .   ? -9.82534  -3.71407  -33.03880 1.000 50.34385  ? 923 HOH A O    1 
HETATM 6658 O  O    . HOH E 4 .   ? 27.72537  3.63693   -9.75887  1.000 58.32400  ? 924 HOH A O    1 
HETATM 6659 O  O    . HOH E 4 .   ? 29.89132  3.56055   -10.02068 1.000 63.50126  ? 925 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N  N   . GLU A 23  ? 0.53756 0.58742 0.71915 0.11012  -0.02579 -0.00305 3   GLU A N   
2    C  CA  . GLU A 23  ? 0.56270 0.58816 0.71928 0.11251  -0.02557 -0.00694 3   GLU A CA  
3    C  C   . GLU A 23  ? 0.52883 0.54602 0.66434 0.10092  -0.02124 -0.00705 3   GLU A C   
4    O  O   . GLU A 23  ? 0.49383 0.52482 0.63417 0.09410  -0.01470 -0.00557 3   GLU A O   
5    C  CB  . GLU A 23  ? 0.58656 0.61194 0.74537 0.12625  -0.01620 -0.01315 3   GLU A CB  
6    C  CG  . GLU A 23  ? 0.83685 0.83551 0.97040 0.12907  -0.01755 -0.01806 3   GLU A CG  
7    C  CD  . GLU A 23  ? 0.92739 0.90489 1.05172 0.12744  -0.03233 -0.01541 3   GLU A CD  
8    O  OE1 . GLU A 23  ? 0.96349 0.94647 1.10225 0.12961  -0.04113 -0.01121 3   GLU A OE1 
9    O  OE2 . GLU A 23  ? 0.88495 0.84059 0.98774 0.12332  -0.03545 -0.01692 3   GLU A OE2 
11   N  N   . ALA A 24  ? 0.46924 0.46391 0.58254 0.09886  -0.02510 -0.00864 4   ALA A N   
12   C  CA  . ALA A 24  ? 0.46080 0.44809 0.55560 0.08781  -0.02265 -0.00818 4   ALA A CA  
13   C  C   . ALA A 24  ? 0.44431 0.43902 0.53591 0.08895  -0.00949 -0.01213 4   ALA A C   
14   O  O   . ALA A 24  ? 0.47023 0.46681 0.56477 0.09931  -0.00263 -0.01671 4   ALA A O   
15   C  CB  . ALA A 24  ? 0.47221 0.43503 0.54672 0.08572  -0.02942 -0.00885 4   ALA A CB  
21   N  N   . PRO A 25  ? 0.46275 0.46103 0.54700 0.07906  -0.00570 -0.01043 5   PRO A N   
22   C  CA  . PRO A 25  ? 0.42521 0.42642 0.50173 0.07983  0.00564  -0.01367 5   PRO A CA  
23   C  C   . PRO A 25  ? 0.44195 0.42378 0.49914 0.08434  0.00533  -0.01912 5   PRO A C   
24   O  O   . PRO A 25  ? 0.46154 0.42675 0.50726 0.08061  -0.00340 -0.01887 5   PRO A O   
25   C  CB  . PRO A 25  ? 0.47071 0.47539 0.54155 0.06771  0.00631  -0.01019 5   PRO A CB  
26   C  CG  . PRO A 25  ? 0.42710 0.42401 0.49471 0.06108  -0.00491 -0.00675 5   PRO A CG  
27   C  CD  . PRO A 25  ? 0.40609 0.40370 0.48611 0.06748  -0.01196 -0.00575 5   PRO A CD  
35   N  N   . ASP A 26  ? 0.41219 0.39603 0.46577 0.09246  0.01477  -0.02393 6   ASP A N   
36   C  CA  . ASP A 26  ? 0.40601 0.37108 0.44067 0.09803  0.01431  -0.03046 6   ASP A CA  
37   C  C   . ASP A 26  ? 0.44562 0.40635 0.46374 0.09007  0.01713  -0.03079 6   ASP A C   
38   O  O   . ASP A 26  ? 0.47100 0.43956 0.48511 0.09228  0.02705  -0.03221 6   ASP A O   
39   C  CB  . ASP A 26  ? 0.45451 0.42342 0.49184 0.11234  0.02287  -0.03616 6   ASP A CB  
40   C  CG  . ASP A 26  ? 0.59853 0.54664 0.61428 0.11885  0.02195  -0.04416 6   ASP A CG  
41   O  OD1 . ASP A 26  ? 0.53482 0.46371 0.53806 0.11350  0.01190  -0.04519 6   ASP A OD1 
42   O  OD2 . ASP A 26  ? 0.69696 0.64808 0.70840 0.12964  0.03138  -0.04949 6   ASP A OD2 
47   N  N   . VAL A 27  ? 0.37536 0.32464 0.38455 0.08053  0.00849  -0.02863 7   VAL A N   
48   C  CA  . VAL A 27  ? 0.38256 0.33040 0.37954 0.07222  0.01022  -0.02789 7   VAL A CA  
49   C  C   . VAL A 27  ? 0.37645 0.30458 0.35812 0.06865  0.00187  -0.03038 7   VAL A C   
50   O  O   . VAL A 27  ? 0.38986 0.30595 0.37189 0.06886  -0.00659 -0.03020 7   VAL A O   
51   C  CB  . VAL A 27  ? 0.37917 0.33884 0.38405 0.06181  0.00973  -0.02124 7   VAL A CB  
52   C  CG1 . VAL A 27  ? 0.42577 0.40482 0.44625 0.06381  0.01783  -0.01869 7   VAL A CG1 
53   C  CG2 . VAL A 27  ? 0.39032 0.34488 0.39958 0.05668  -0.00025 -0.01730 7   VAL A CG2 
63   N  N   . ASP A 28  ? 0.37443 0.29953 0.34321 0.06507  0.00404  -0.03224 8   ASP A N   
64   C  CA  . ASP A 28  ? 0.39726 0.30676 0.35315 0.05958  -0.00370 -0.03395 8   ASP A CA  
65   C  C   . ASP A 28  ? 0.37370 0.29116 0.32965 0.04872  -0.00365 -0.02874 8   ASP A C   
66   O  O   . ASP A 28  ? 0.34671 0.27172 0.29832 0.04792  0.00241  -0.02895 8   ASP A O   
67   C  CB  . ASP A 28  ? 0.42631 0.32482 0.36670 0.06652  -0.00225 -0.04177 8   ASP A CB  
68   C  CG  . ASP A 28  ? 0.43083 0.31408 0.35914 0.06046  -0.01098 -0.04393 8   ASP A CG  
69   O  OD1 . ASP A 28  ? 0.41306 0.29715 0.34534 0.05015  -0.01620 -0.03861 8   ASP A OD1 
70   O  OD2 . ASP A 28  ? 0.49743 0.36805 0.41191 0.06621  -0.01260 -0.05122 8   ASP A OD2 
75   N  N   . LEU A 29  ? 0.33003 0.24571 0.29045 0.04081  -0.01014 -0.02374 9   LEU A N   
76   C  CA  . LEU A 29  ? 0.33438 0.25856 0.29569 0.03155  -0.00958 -0.01889 9   LEU A CA  
77   C  C   . LEU A 29  ? 0.33375 0.25206 0.28492 0.02693  -0.01201 -0.02051 9   LEU A C   
78   O  O   . LEU A 29  ? 0.32517 0.25105 0.27700 0.02054  -0.01093 -0.01715 9   LEU A O   
79   C  CB  . LEU A 29  ? 0.31394 0.23877 0.28191 0.02559  -0.01482 -0.01295 9   LEU A CB  
80   C  CG  . LEU A 29  ? 0.35891 0.29292 0.33799 0.02901  -0.01296 -0.01070 9   LEU A CG  
81   C  CD1 . LEU A 29  ? 0.36961 0.30169 0.35136 0.02344  -0.01934 -0.00493 9   LEU A CD1 
82   C  CD2 . LEU A 29  ? 0.33977 0.28920 0.32433 0.02863  -0.00546 -0.00992 9   LEU A CD2 
94   N  N   . ALA A 30  ? 0.33681 0.24203 0.27887 0.03042  -0.01565 -0.02592 10  ALA A N   
95   C  CA  . ALA A 30  ? 0.37626 0.27650 0.30874 0.02709  -0.01853 -0.02842 10  ALA A CA  
96   C  C   . ALA A 30  ? 0.37993 0.28238 0.30272 0.03378  -0.01246 -0.03328 10  ALA A C   
97   O  O   . ALA A 30  ? 0.38496 0.28275 0.29803 0.03240  -0.01534 -0.03604 10  ALA A O   
98   C  CB  . ALA A 30  ? 0.43098 0.31331 0.35838 0.02560  -0.02833 -0.03146 10  ALA A CB  
104  N  N   . ASP A 31  ? 0.36588 0.27562 0.29115 0.04099  -0.00429 -0.03398 11  ASP A N   
105  C  CA  . ASP A 31  ? 0.38266 0.29518 0.29824 0.04771  0.00303  -0.03741 11  ASP A CA  
106  C  C   . ASP A 31  ? 0.37342 0.30060 0.29319 0.04366  0.00967  -0.03207 11  ASP A C   
107  O  O   . ASP A 31  ? 0.36130 0.29976 0.29380 0.04180  0.01390  -0.02742 11  ASP A O   
108  C  CB  . ASP A 31  ? 0.39651 0.30968 0.31413 0.05795  0.00900  -0.04053 11  ASP A CB  
109  C  CG  . ASP A 31  ? 0.47903 0.39518 0.38564 0.06609  0.01809  -0.04378 11  ASP A CG  
110  O  OD1 . ASP A 31  ? 0.44019 0.35930 0.33819 0.06369  0.02060  -0.04254 11  ASP A OD1 
111  O  OD2 . ASP A 31  ? 0.57650 0.49138 0.48247 0.07570  0.02267  -0.04762 11  ASP A OD2 
116  N  N   . GLY A 32  ? 0.35817 0.28423 0.26707 0.04242  0.00971  -0.03284 12  GLY A N   
117  C  CA  . GLY A 32  ? 0.34486 0.28259 0.25672 0.03909  0.01544  -0.02778 12  GLY A CA  
118  C  C   . GLY A 32  ? 0.34165 0.28928 0.25825 0.04372  0.02605  -0.02545 12  GLY A C   
119  O  O   . GLY A 32  ? 0.33721 0.29481 0.26216 0.03961  0.03002  -0.02023 12  GLY A O   
123  N  N   . ASN A 33  ? 0.33945 0.28472 0.25194 0.05217  0.03070  -0.02914 13  ASN A N   
124  C  CA  . ASN A 33  ? 0.37014 0.32722 0.29004 0.05633  0.04166  -0.02611 13  ASN A CA  
125  C  C   . ASN A 33  ? 0.34892 0.31660 0.28986 0.05261  0.04214  -0.02179 13  ASN A C   
126  O  O   . ASN A 33  ? 0.33733 0.31719 0.28863 0.05170  0.04951  -0.01711 13  ASN A O   
127  C  CB  . ASN A 33  ? 0.38556 0.33870 0.29673 0.06717  0.04699  -0.03137 13  ASN A CB  
128  C  CG  . ASN A 33  ? 0.44154 0.38651 0.33000 0.07169  0.04890  -0.03479 13  ASN A CG  
129  O  OD1 . ASN A 33  ? 0.44100 0.38938 0.32397 0.06814  0.05147  -0.03074 13  ASN A OD1 
130  N  ND2 . ASN A 33  ? 0.56961 0.50255 0.44406 0.07968  0.04671  -0.04238 13  ASN A ND2 
137  N  N   . PHE A 34  ? 0.31560 0.27857 0.26303 0.05006  0.03393  -0.02283 14  PHE A N   
138  C  CA  . PHE A 34  ? 0.29784 0.26982 0.26299 0.04618  0.03273  -0.01866 14  PHE A CA  
139  C  C   . PHE A 34  ? 0.29472 0.27435 0.26500 0.03814  0.03339  -0.01351 14  PHE A C   
140  O  O   . PHE A 34  ? 0.30266 0.29291 0.28624 0.03635  0.03676  -0.00985 14  PHE A O   
141  C  CB  . PHE A 34  ? 0.30232 0.26573 0.26981 0.04435  0.02309  -0.01988 14  PHE A CB  
142  C  CG  . PHE A 34  ? 0.28928 0.26014 0.27147 0.03980  0.02003  -0.01548 14  PHE A CG  
143  C  CD1 . PHE A 34  ? 0.31012 0.28805 0.30570 0.04431  0.02164  -0.01480 14  PHE A CD1 
144  C  CD2 . PHE A 34  ? 0.27624 0.24775 0.25875 0.03155  0.01559  -0.01214 14  PHE A CD2 
145  C  CE1 . PHE A 34  ? 0.32548 0.30982 0.33355 0.04030  0.01760  -0.01101 14  PHE A CE1 
146  C  CE2 . PHE A 34  ? 0.29870 0.27608 0.29194 0.02781  0.01240  -0.00857 14  PHE A CE2 
147  C  CZ  . PHE A 34  ? 0.30420 0.28749 0.30992 0.03190  0.01267  -0.00800 14  PHE A CZ  
157  N  N   . TYR A 35  ? 0.28782 0.26211 0.24851 0.03337  0.02969  -0.01338 15  TYR A N   
158  C  CA  . TYR A 35  ? 0.29540 0.27491 0.25991 0.02654  0.02922  -0.00937 15  TYR A CA  
159  C  C   . TYR A 35  ? 0.32361 0.30849 0.28652 0.02700  0.03672  -0.00678 15  TYR A C   
160  O  O   . TYR A 35  ? 0.31925 0.30893 0.28812 0.02217  0.03727  -0.00330 15  TYR A O   
161  C  CB  . TYR A 35  ? 0.29156 0.26461 0.24834 0.02198  0.02251  -0.01005 15  TYR A CB  
162  C  CG  . TYR A 35  ? 0.28339 0.25132 0.24290 0.02020  0.01546  -0.01090 15  TYR A CG  
163  C  CD1 . TYR A 35  ? 0.26370 0.23551 0.23166 0.01589  0.01257  -0.00792 15  TYR A CD1 
164  C  CD2 . TYR A 35  ? 0.28508 0.24300 0.23760 0.02300  0.01140  -0.01461 15  TYR A CD2 
165  C  CE1 . TYR A 35  ? 0.26284 0.22910 0.23190 0.01420  0.00629  -0.00757 15  TYR A CE1 
166  C  CE2 . TYR A 35  ? 0.28914 0.24106 0.24427 0.02112  0.00502  -0.01450 15  TYR A CE2 
167  C  CZ  . TYR A 35  ? 0.29227 0.24868 0.25557 0.01662  0.00278  -0.01047 15  TYR A CZ  
168  O  OH  . TYR A 35  ? 0.31936 0.26909 0.28426 0.01458  -0.00357 -0.00917 15  TYR A OH  
178  N  N   . ALA A 36  ? 0.31221 0.29589 0.26716 0.03297  0.04261  -0.00823 16  ALA A N   
179  C  CA  . ALA A 36  ? 0.32391 0.31252 0.27679 0.03361  0.05071  -0.00455 16  ALA A CA  
180  C  C   . ALA A 36  ? 0.37484 0.37444 0.34263 0.03508  0.05796  -0.00147 16  ALA A C   
181  O  O   . ALA A 36  ? 0.35427 0.35966 0.32453 0.03411  0.06518  0.00316  16  ALA A O   
182  C  CB  . ALA A 36  ? 0.36466 0.34630 0.29871 0.03936  0.05367  -0.00705 16  ALA A CB  
188  N  N   . SER A 37  ? 0.33757 0.34043 0.31670 0.03692  0.05562  -0.00332 17  SER A N   
189  C  CA  . SER A 37  ? 0.40335 0.41860 0.40035 0.03836  0.06115  -0.00051 17  SER A CA  
190  C  C   . SER A 37  ? 0.34024 0.36182 0.35283 0.03036  0.05705  0.00341  17  SER A C   
191  O  O   . SER A 37  ? 0.39004 0.40702 0.40315 0.02641  0.04823  0.00206  17  SER A O   
192  C  CB  . SER A 37  ? 0.35945 0.37468 0.36153 0.04512  0.05937  -0.00462 17  SER A CB  
193  O  OG  . SER A 37  ? 0.45721 0.48638 0.48064 0.04538  0.06267  -0.00141 17  SER A OG  
199  N  N   . ARG A 38  ? 0.40218 0.43395 0.42707 0.02789  0.06330  0.00833  18  ARG A N   
200  C  CA  . ARG A 38  ? 0.41633 0.45424 0.45762 0.02087  0.05904  0.01144  18  ARG A CA  
201  C  C   . ARG A 38  ? 0.37790 0.42421 0.43674 0.02262  0.05551  0.01065  18  ARG A C   
202  O  O   . ARG A 38  ? 0.44396 0.49718 0.51872 0.01733  0.05186  0.01323  18  ARG A O   
203  C  CB  . ARG A 38  ? 0.45512 0.49975 0.50402 0.01681  0.06631  0.01741  18  ARG A CB  
204  C  CG  . ARG A 38  ? 0.48833 0.52290 0.51868 0.01542  0.06825  0.01845  18  ARG A CG  
205  C  CD  . ARG A 38  ? 0.53586 0.57372 0.57245 0.01023  0.07367  0.02504  18  ARG A CD  
206  N  NE  . ARG A 38  ? 0.49601 0.52294 0.51479 0.00937  0.07362  0.02590  18  ARG A NE  
207  C  CZ  . ARG A 38  ? 0.55067 0.56945 0.56509 0.00504  0.06619  0.02473  18  ARG A CZ  
208  N  NH1 . ARG A 38  ? 0.67897 0.69816 0.70281 0.00113  0.05827  0.02228  18  ARG A NH1 
209  N  NH2 . ARG A 38  ? 0.44664 0.45671 0.44634 0.00528  0.06670  0.02600  18  ARG A NH2 
223  N  N   . GLU A 39  ? 0.38396 0.42858 0.43958 0.03004  0.05554  0.00694  19  GLU A N   
224  C  CA  . GLU A 39  ? 0.44601 0.49504 0.51496 0.03268  0.04981  0.00554  19  GLU A CA  
225  C  C   . GLU A 39  ? 0.35891 0.39541 0.41723 0.03227  0.03936  0.00203  19  GLU A C   
226  O  O   . GLU A 39  ? 0.34046 0.37825 0.40747 0.03471  0.03351  0.00121  19  GLU A O   
227  C  CB  . GLU A 39  ? 0.46759 0.52415 0.54318 0.04229  0.05739  0.00426  19  GLU A CB  
228  C  CG  . GLU A 39  ? 0.67600 0.74619 0.76127 0.04280  0.06981  0.00881  19  GLU A CG  
229  C  CD  . GLU A 39  ? 0.78210 0.86581 0.88226 0.05174  0.07752  0.00876  19  GLU A CD  
230  O  OE1 . GLU A 39  ? 0.81931 0.90435 0.91053 0.05877  0.08821  0.00795  19  GLU A OE1 
231  O  OE2 . GLU A 39  ? 0.85044 0.94392 0.97114 0.05227  0.07295  0.00951  19  GLU A OE2 
238  N  N   . ALA A 40  ? 0.32964 0.35485 0.37077 0.02883  0.03658  0.00073  20  ALA A N   
239  C  CA  . ALA A 40  ? 0.32287 0.33785 0.35568 0.02696  0.02736  -0.00115 20  ALA A CA  
240  C  C   . ALA A 40  ? 0.28562 0.30430 0.32864 0.02204  0.01997  0.00103  20  ALA A C   
241  O  O   . ALA A 40  ? 0.28415 0.29861 0.32743 0.02293  0.01280  0.00055  20  ALA A O   
242  C  CB  . ALA A 40  ? 0.35087 0.35665 0.36694 0.02329  0.02651  -0.00202 20  ALA A CB  
248  N  N   . ARG A 41  ? 0.27847 0.30327 0.32820 0.01665  0.02078  0.00345  21  ARG A N   
249  C  CA  . ARG A 41  ? 0.25939 0.28544 0.31521 0.01209  0.01252  0.00452  21  ARG A CA  
250  C  C   . ARG A 41  ? 0.25298 0.28696 0.32534 0.01529  0.00886  0.00527  21  ARG A C   
251  O  O   . ARG A 41  ? 0.23978 0.27121 0.31258 0.01406  0.00006  0.00545  21  ARG A O   
252  C  CB  . ARG A 41  ? 0.25780 0.28648 0.31654 0.00576  0.01292  0.00607  21  ARG A CB  
253  C  CG  . ARG A 41  ? 0.28526 0.30457 0.32648 0.00306  0.01360  0.00499  21  ARG A CG  
254  C  CD  . ARG A 41  ? 0.33025 0.34718 0.36964 -0.00245 0.00878  0.00494  21  ARG A CD  
255  N  NE  . ARG A 41  ? 0.32458 0.34591 0.37374 -0.00570 0.01188  0.00673  21  ARG A NE  
256  C  CZ  . ARG A 41  ? 0.38162 0.39961 0.42486 -0.00710 0.01687  0.00755  21  ARG A CZ  
257  N  NH1 . ARG A 41  ? 0.36399 0.37592 0.39276 -0.00501 0.01956  0.00647  21  ARG A NH1 
258  N  NH2 . ARG A 41  ? 0.34678 0.36710 0.39931 -0.01099 0.01830  0.00976  21  ARG A NH2 
272  N  N   . ALA A 42  ? 0.24842 0.29220 0.33394 0.02004  0.01544  0.00590  22  ALA A N   
273  C  CA  . ALA A 42  ? 0.27324 0.32546 0.37574 0.02463  0.01200  0.00638  22  ALA A CA  
274  C  C   . ALA A 42  ? 0.26903 0.31129 0.36285 0.03024  0.00645  0.00415  22  ALA A C   
275  O  O   . ALA A 42  ? 0.28658 0.33007 0.38854 0.03186  -0.00176 0.00489  22  ALA A O   
276  C  CB  . ALA A 42  ? 0.29761 0.36348 0.41568 0.02956  0.02204  0.00755  22  ALA A CB  
282  N  N   . ALA A 43  ? 0.24839 0.28016 0.32606 0.03329  0.01022  0.00160  23  ALA A N   
283  C  CA  . ALA A 43  ? 0.28354 0.30324 0.35197 0.03760  0.00465  -0.00036 23  ALA A CA  
284  C  C   . ALA A 43  ? 0.26509 0.27615 0.32464 0.03152  -0.00488 0.00145  23  ALA A C   
285  O  O   . ALA A 43  ? 0.25894 0.26542 0.32000 0.03364  -0.01250 0.00243  23  ALA A O   
286  C  CB  . ALA A 43  ? 0.28726 0.29666 0.33987 0.04085  0.00970  -0.00378 23  ALA A CB  
292  N  N   . TYR A 44  ? 0.25502 0.26408 0.30526 0.02441  -0.00440 0.00226  24  TYR A N   
293  C  CA  . TYR A 44  ? 0.25856 0.26089 0.29957 0.01910  -0.01199 0.00410  24  TYR A CA  
294  C  C   . TYR A 44  ? 0.27345 0.28118 0.32466 0.01829  -0.01957 0.00615  24  TYR A C   
295  O  O   . TYR A 44  ? 0.25956 0.26057 0.30435 0.01748  -0.02729 0.00802  24  TYR A O   
296  C  CB  . TYR A 44  ? 0.25362 0.25561 0.28575 0.01285  -0.00928 0.00414  24  TYR A CB  
297  C  CG  . TYR A 44  ? 0.24222 0.23892 0.26288 0.01229  -0.00370 0.00261  24  TYR A CG  
298  C  CD1 . TYR A 44  ? 0.25214 0.24007 0.26474 0.01480  -0.00420 0.00149  24  TYR A CD1 
299  C  CD2 . TYR A 44  ? 0.24616 0.24589 0.26417 0.00898  0.00098  0.00231  24  TYR A CD2 
300  C  CE1 . TYR A 44  ? 0.26381 0.24725 0.26624 0.01381  -0.00036 -0.00013 24  TYR A CE1 
301  C  CE2 . TYR A 44  ? 0.24812 0.24341 0.25572 0.00858  0.00498  0.00113  24  TYR A CE2 
302  C  CZ  . TYR A 44  ? 0.26447 0.25249 0.26486 0.01096  0.00426  -0.00018 24  TYR A CZ  
303  O  OH  . TYR A 44  ? 0.27345 0.25739 0.26417 0.01030  0.00683  -0.00151 24  TYR A OH  
313  N  N   . ARG A 45  ? 0.23490 0.25466 0.30183 0.01800  -0.01792 0.00628  25  ARG A N   
314  C  CA  . ARG A 45  ? 0.26128 0.28723 0.34006 0.01715  -0.02632 0.00785  25  ARG A CA  
315  C  C   . ARG A 45  ? 0.24686 0.27084 0.33087 0.02354  -0.03248 0.00882  25  ARG A C   
316  O  O   . ARG A 45  ? 0.26516 0.28571 0.34695 0.02275  -0.04237 0.01069  25  ARG A O   
317  C  CB  . ARG A 45  ? 0.33241 0.37304 0.43143 0.01604  -0.02280 0.00815  25  ARG A CB  
318  C  CG  . ARG A 45  ? 0.43430 0.47601 0.53143 0.00841  -0.02287 0.00808  25  ARG A CG  
319  C  CD  . ARG A 45  ? 0.50885 0.56411 0.62897 0.00583  -0.02524 0.00939  25  ARG A CD  
320  N  NE  . ARG A 45  ? 0.55085 0.61836 0.68809 0.00915  -0.01556 0.01076  25  ARG A NE  
321  C  CZ  . ARG A 45  ? 0.57026 0.63916 0.70536 0.00796  -0.00480 0.01128  25  ARG A CZ  
322  N  NH1 . ARG A 45  ? 0.44179 0.50104 0.56048 0.00341  -0.00281 0.01042  25  ARG A NH1 
323  N  NH2 . ARG A 45  ? 0.64015 0.72080 0.78984 0.01192  0.00436  0.01296  25  ARG A NH2 
337  N  N   . TRP A 46  ? 0.26925 0.29508 0.35991 0.03060  -0.02692 0.00747  26  TRP A N   
338  C  CA  . TRP A 46  ? 0.24772 0.27012 0.34338 0.03803  -0.03244 0.00789  26  TRP A CA  
339  C  C   . TRP A 46  ? 0.25238 0.25765 0.32909 0.03658  -0.03930 0.00941  26  TRP A C   
340  O  O   . TRP A 46  ? 0.26773 0.26887 0.34515 0.03829  -0.04885 0.01205  26  TRP A O   
341  C  CB  . TRP A 46  ? 0.27147 0.29665 0.37401 0.04667  -0.02410 0.00503  26  TRP A CB  
342  C  CG  . TRP A 46  ? 0.26660 0.29047 0.37851 0.05559  -0.02972 0.00505  26  TRP A CG  
343  C  CD1 . TRP A 46  ? 0.29581 0.33447 0.43063 0.06135  -0.03095 0.00570  26  TRP A CD1 
344  C  CD2 . TRP A 46  ? 0.31172 0.31848 0.41172 0.05972  -0.03585 0.00490  26  TRP A CD2 
345  N  NE1 . TRP A 46  ? 0.33672 0.36842 0.47413 0.06978  -0.03754 0.00561  26  TRP A NE1 
346  C  CE2 . TRP A 46  ? 0.31709 0.32807 0.43259 0.06876  -0.04066 0.00516  26  TRP A CE2 
347  C  CE3 . TRP A 46  ? 0.32032 0.30884 0.39941 0.05642  -0.03789 0.00494  26  TRP A CE3 
348  C  CZ2 . TRP A 46  ? 0.38996 0.38543 0.49902 0.07487  -0.04771 0.00536  26  TRP A CZ2 
349  C  CZ3 . TRP A 46  ? 0.33925 0.31295 0.41281 0.06143  -0.04464 0.00550  26  TRP A CZ3 
350  C  CH2 . TRP A 46  ? 0.34431 0.32043 0.43192 0.07073  -0.04963 0.00564  26  TRP A CH2 
361  N  N   . MET A 47  ? 0.25430 0.24978 0.31432 0.03312  -0.03469 0.00840  27  MET A N   
362  C  CA  . MET A 47  ? 0.26333 0.24363 0.30665 0.03052  -0.03998 0.01072  27  MET A CA  
363  C  C   . MET A 47  ? 0.27708 0.25657 0.31464 0.02529  -0.04781 0.01462  27  MET A C   
364  O  O   . MET A 47  ? 0.27721 0.24834 0.30980 0.02641  -0.05581 0.01818  27  MET A O   
365  C  CB  . MET A 47  ? 0.27439 0.24823 0.30393 0.02628  -0.03368 0.00920  27  MET A CB  
366  C  CG  . MET A 47  ? 0.28938 0.26250 0.32050 0.03125  -0.02631 0.00482  27  MET A CG  
367  S  SD  . MET A 47  ? 0.29326 0.26015 0.30845 0.02497  -0.02131 0.00364  27  MET A SD  
368  C  CE  . MET A 47  ? 0.31564 0.28500 0.33344 0.03162  -0.01276 -0.00173 27  MET A CE  
378  N  N   . ARG A 48  ? 0.25883 0.24619 0.29640 0.02009  -0.04604 0.01398  28  ARG A N   
379  C  CA  . ARG A 48  ? 0.26934 0.25445 0.29751 0.01546  -0.05297 0.01664  28  ARG A CA  
380  C  C   . ARG A 48  ? 0.29560 0.28345 0.33286 0.01875  -0.06309 0.01866  28  ARG A C   
381  O  O   . ARG A 48  ? 0.32046 0.30155 0.34644 0.01724  -0.07088 0.02205  28  ARG A O   
382  C  CB  . ARG A 48  ? 0.27272 0.26444 0.29944 0.01018  -0.04968 0.01443  28  ARG A CB  
383  C  CG  . ARG A 48  ? 0.26244 0.25133 0.27886 0.00692  -0.04081 0.01290  28  ARG A CG  
384  C  CD  . ARG A 48  ? 0.28910 0.28083 0.29969 0.00202  -0.03917 0.01125  28  ARG A CD  
385  N  NE  . ARG A 48  ? 0.29695 0.29784 0.32240 0.00173  -0.03970 0.00915  28  ARG A NE  
386  C  CZ  . ARG A 48  ? 0.28175 0.28872 0.31685 0.00181  -0.03231 0.00739  28  ARG A CZ  
387  N  NH1 . ARG A 48  ? 0.26849 0.27288 0.29772 0.00233  -0.02440 0.00666  28  ARG A NH1 
388  N  NH2 . ARG A 48  ? 0.28228 0.29827 0.33357 0.00115  -0.03322 0.00680  28  ARG A NH2 
402  N  N   . ALA A 49  ? 0.26304 0.26143 0.32081 0.02354  -0.06311 0.01699  29  ALA A N   
403  C  CA  . ALA A 49  ? 0.27293 0.27623 0.34269 0.02698  -0.07341 0.01879  29  ALA A CA  
404  C  C   . ALA A 49  ? 0.31600 0.31131 0.38666 0.03410  -0.07866 0.02130  29  ALA A C   
405  O  O   . ALA A 49  ? 0.35605 0.35112 0.43034 0.03658  -0.08949 0.02409  29  ALA A O   
406  C  CB  . ALA A 49  ? 0.28388 0.30456 0.37875 0.02874  -0.07122 0.01653  29  ALA A CB  
412  N  N   . ASN A 50  ? 0.28451 0.27210 0.35136 0.03762  -0.07231 0.02024  30  ASN A N   
413  C  CA  . ASN A 50  ? 0.28652 0.26633 0.35736 0.04572  -0.07680 0.02148  30  ASN A CA  
414  C  C   . ASN A 50  ? 0.32302 0.28336 0.37531 0.04490  -0.07761 0.02381  30  ASN A C   
415  O  O   . ASN A 50  ? 0.32981 0.27940 0.38060 0.04967  -0.08533 0.02696  30  ASN A O   
416  C  CB  . ASN A 50  ? 0.31413 0.30332 0.40304 0.05366  -0.06933 0.01702  30  ASN A CB  
417  C  CG  . ASN A 50  ? 0.29390 0.30331 0.40603 0.05556  -0.06943 0.01611  30  ASN A CG  
418  O  OD1 . ASN A 50  ? 0.34475 0.35947 0.47060 0.06079  -0.07773 0.01787  30  ASN A OD1 
419  N  ND2 . ASN A 50  ? 0.31036 0.33117 0.42801 0.05119  -0.06074 0.01384  30  ASN A ND2 
426  N  N   . GLN A 51  ? 0.32598 0.28148 0.36541 0.03894  -0.07014 0.02257  31  GLN A N   
427  C  CA  . GLN A 51  ? 0.31991 0.25815 0.34386 0.03667  -0.07089 0.02508  31  GLN A CA  
428  C  C   . GLN A 51  ? 0.26618 0.20468 0.27729 0.02779  -0.06457 0.02517  31  GLN A C   
429  O  O   . GLN A 51  ? 0.29591 0.23477 0.30615 0.02699  -0.05702 0.02123  31  GLN A O   
430  C  CB  . GLN A 51  ? 0.34010 0.27027 0.36788 0.04340  -0.06797 0.02119  31  GLN A CB  
431  C  CG  . GLN A 51  ? 0.39258 0.30207 0.40673 0.04135  -0.07259 0.02485  31  GLN A CG  
432  C  CD  . GLN A 51  ? 0.50961 0.40831 0.52428 0.04695  -0.07002 0.01971  31  GLN A CD  
433  O  OE1 . GLN A 51  ? 0.46561 0.37102 0.48351 0.04899  -0.06197 0.01347  31  GLN A OE1 
434  N  NE2 . GLN A 51  ? 0.53158 0.41183 0.54130 0.04933  -0.07728 0.02243  31  GLN A NE2 
443  N  N   . PRO A 52  ? 0.29383 0.23330 0.29507 0.02179  -0.06753 0.02923  32  PRO A N   
444  C  CA  . PRO A 52  ? 0.28812 0.23166 0.27996 0.01460  -0.06086 0.02846  32  PRO A CA  
445  C  C   . PRO A 52  ? 0.29813 0.23313 0.28160 0.01107  -0.05604 0.02893  32  PRO A C   
446  O  O   . PRO A 52  ? 0.28710 0.22721 0.26859 0.00767  -0.04895 0.02606  32  PRO A O   
447  C  CB  . PRO A 52  ? 0.33748 0.28003 0.31760 0.01060  -0.06639 0.03338  32  PRO A CB  
448  C  CG  . PRO A 52  ? 0.38047 0.32432 0.36868 0.01582  -0.07557 0.03461  32  PRO A CG  
449  C  CD  . PRO A 52  ? 0.34330 0.28201 0.34249 0.02256  -0.07714 0.03379  32  PRO A CD  
457  N  N   . VAL A 53  ? 0.28363 0.20511 0.26157 0.01100  -0.06061 0.03323  33  VAL A N   
458  C  CA  . VAL A 53  ? 0.31549 0.22764 0.28881 0.00802  -0.05785 0.03322  33  VAL A CA  
459  C  C   . VAL A 53  ? 0.29510 0.20140 0.27725 0.01568  -0.05874 0.02811  33  VAL A C   
460  O  O   . VAL A 53  ? 0.32757 0.22241 0.31113 0.02013  -0.06530 0.03003  33  VAL A O   
461  C  CB  . VAL A 53  ? 0.32509 0.22547 0.28727 0.00224  -0.06204 0.04143  33  VAL A CB  
462  C  CG1 . VAL A 53  ? 0.33506 0.22611 0.29512 -0.00179 -0.06013 0.04128  33  VAL A CG1 
463  C  CG2 . VAL A 53  ? 0.32960 0.23833 0.28214 -0.00390 -0.05942 0.04567  33  VAL A CG2 
473  N  N   . PHE A 54  ? 0.31876 0.23327 0.30641 0.01803  -0.05181 0.02140  34  PHE A N   
474  C  CA  . PHE A 54  ? 0.31038 0.22440 0.30663 0.02671  -0.05004 0.01527  34  PHE A CA  
475  C  C   . PHE A 54  ? 0.32398 0.22346 0.31409 0.02728  -0.05042 0.01248  34  PHE A C   
476  O  O   . PHE A 54  ? 0.35319 0.24960 0.33561 0.02039  -0.04864 0.01314  34  PHE A O   
477  C  CB  . PHE A 54  ? 0.29057 0.22089 0.29372 0.02802  -0.04177 0.01058  34  PHE A CB  
478  C  CG  . PHE A 54  ? 0.30521 0.23822 0.31636 0.03680  -0.03729 0.00453  34  PHE A CG  
479  C  CD1 . PHE A 54  ? 0.32294 0.26017 0.34627 0.04471  -0.03955 0.00396  34  PHE A CD1 
480  C  CD2 . PHE A 54  ? 0.32019 0.25328 0.32685 0.03742  -0.03047 -0.00032 34  PHE A CD2 
481  C  CE1 . PHE A 54  ? 0.36486 0.30638 0.39613 0.05373  -0.03407 -0.00145 34  PHE A CE1 
482  C  CE2 . PHE A 54  ? 0.34265 0.27879 0.35471 0.04612  -0.02530 -0.00568 34  PHE A CE2 
483  C  CZ  . PHE A 54  ? 0.33098 0.27178 0.35565 0.05438  -0.02657 -0.00618 34  PHE A CZ  
493  N  N   . ARG A 55  ? 0.34677 0.23770 0.34095 0.03599  -0.05289 0.00873  35  ARG A N   
494  C  CA  . ARG A 55  ? 0.33417 0.21202 0.32255 0.03841  -0.05254 0.00329  35  ARG A CA  
495  C  C   . ARG A 55  ? 0.35307 0.23889 0.34627 0.04740  -0.04527 -0.00470 35  ARG A C   
496  O  O   . ARG A 55  ? 0.37003 0.26253 0.37346 0.05599  -0.04422 -0.00628 35  ARG A O   
497  C  CB  . ARG A 55  ? 0.40041 0.25781 0.38647 0.04198  -0.06136 0.00443  35  ARG A CB  
498  C  CG  . ARG A 55  ? 0.43413 0.28093 0.41311 0.03171  -0.06789 0.01317  35  ARG A CG  
499  C  CD  . ARG A 55  ? 0.43774 0.26097 0.41255 0.03328  -0.07614 0.01362  35  ARG A CD  
500  N  NE  . ARG A 55  ? 0.45039 0.26390 0.41937 0.02304  -0.08176 0.02335  35  ARG A NE  
501  C  CZ  . ARG A 55  ? 0.42991 0.23856 0.39341 0.01290  -0.08173 0.02584  35  ARG A CZ  
502  N  NH1 . ARG A 55  ? 0.41949 0.23102 0.38170 0.01156  -0.07763 0.01902  35  ARG A NH1 
503  N  NH2 . ARG A 55  ? 0.43065 0.23139 0.39012 0.00391  -0.08616 0.03589  35  ARG A NH2 
517  N  N   . ASP A 56  ? 0.36787 0.25315 0.35380 0.04565  -0.04041 -0.00930 36  ASP A N   
518  C  CA  . ASP A 56  ? 0.35738 0.25068 0.34507 0.05364  -0.03225 -0.01611 36  ASP A CA  
519  C  C   . ASP A 56  ? 0.36302 0.24176 0.34761 0.06431  -0.03438 -0.02276 36  ASP A C   
520  O  O   . ASP A 56  ? 0.40023 0.26320 0.38382 0.06629  -0.04260 -0.02200 36  ASP A O   
521  C  CB  . ASP A 56  ? 0.35499 0.25389 0.33489 0.04825  -0.02643 -0.01799 36  ASP A CB  
522  C  CG  . ASP A 56  ? 0.38281 0.26560 0.34999 0.04585  -0.03042 -0.02169 36  ASP A CG  
523  O  OD1 . ASP A 56  ? 0.39236 0.25753 0.35561 0.04824  -0.03758 -0.02364 36  ASP A OD1 
524  O  OD2 . ASP A 56  ? 0.39173 0.27947 0.35305 0.04157  -0.02672 -0.02282 36  ASP A OD2 
529  N  N   . ARG A 57  ? 0.39190 0.27530 0.37423 0.07210  -0.02664 -0.02943 37  ARG A N   
530  C  CA  A ARG A 57  ? 0.41777 0.28936 0.39723 0.08454  -0.02714 -0.03672 37  ARG A CA  
531  C  CA  B ARG A 57  ? 0.41766 0.28909 0.39742 0.08449  -0.02741 -0.03654 37  ARG A CA  
532  C  C   . ARG A 57  ? 0.43300 0.27944 0.39840 0.08317  -0.03588 -0.04065 37  ARG A C   
533  O  O   . ARG A 57  ? 0.52001 0.35101 0.48299 0.09254  -0.04011 -0.04578 37  ARG A O   
534  C  CB  A ARG A 57  ? 0.47687 0.35947 0.45443 0.09305  -0.01569 -0.04271 37  ARG A CB  
535  C  CB  B ARG A 57  ? 0.47600 0.35902 0.45521 0.09376  -0.01593 -0.04247 37  ARG A CB  
536  C  CG  A ARG A 57  ? 0.47223 0.34950 0.43330 0.08929  -0.01322 -0.04669 37  ARG A CG  
537  C  CG  B ARG A 57  ? 0.47261 0.35296 0.43628 0.09091  -0.01172 -0.04657 37  ARG A CG  
538  C  CD  A ARG A 57  ? 0.52944 0.41983 0.48799 0.09683  -0.00076 -0.05057 37  ARG A CD  
539  C  CD  B ARG A 57  ? 0.52409 0.41988 0.48885 0.09930  0.00122  -0.04974 37  ARG A CD  
540  N  NE  A ARG A 57  ? 0.50633 0.39350 0.46521 0.11162  0.00320  -0.05713 37  ARG A NE  
541  N  NE  B ARG A 57  ? 0.55720 0.44993 0.50521 0.09820  0.00540  -0.05366 37  ARG A NE  
542  C  CZ  A ARG A 57  ? 0.58117 0.45027 0.52394 0.11983  0.00122  -0.06594 37  ARG A CZ  
543  C  CZ  B ARG A 57  ? 0.51743 0.42506 0.46444 0.10007  0.01650  -0.05311 37  ARG A CZ  
544  N  NH1 A ARG A 57  ? 0.58724 0.43981 0.51298 0.11406  -0.00550 -0.06920 37  ARG A NH1 
545  N  NH1 B ARG A 57  ? 0.51953 0.44742 0.48312 0.10137  0.02472  -0.04830 37  ARG A NH1 
546  N  NH2 A ARG A 57  ? 0.58503 0.45277 0.52912 0.13450  0.00580  -0.07195 37  ARG A NH2 
547  N  NH2 B ARG A 57  ? 0.55028 0.45196 0.47937 0.10036  0.01886  -0.05710 37  ARG A NH2 
574  N  N   . ASN A 58  ? 0.44262 0.28447 0.39980 0.07185  -0.03912 -0.03841 38  ASN A N   
575  C  CA  . ASN A 58  ? 0.44877 0.26796 0.39490 0.06792  -0.04845 -0.04101 38  ASN A CA  
576  C  C   . ASN A 58  ? 0.48504 0.29548 0.43503 0.05768  -0.05768 -0.03247 38  ASN A C   
577  O  O   . ASN A 58  ? 0.50678 0.29984 0.45003 0.05159  -0.06574 -0.03261 38  ASN A O   
578  C  CB  . ASN A 58  ? 0.46091 0.28110 0.39647 0.06195  -0.04667 -0.04396 38  ASN A CB  
579  C  CG  . ASN A 58  ? 0.48091 0.30699 0.40903 0.07189  -0.03799 -0.05193 38  ASN A CG  
580  O  OD1 . ASN A 58  ? 0.55768 0.39803 0.48378 0.06898  -0.03097 -0.05108 38  ASN A OD1 
581  N  ND2 . ASN A 58  ? 0.50118 0.31648 0.42506 0.08416  -0.03798 -0.05923 38  ASN A ND2 
588  N  N   . GLY A 59  ? 0.43657 0.25859 0.39684 0.05544  -0.05680 -0.02486 39  GLY A N   
589  C  CA  . GLY A 59  ? 0.44137 0.25689 0.40385 0.04642  -0.06419 -0.01573 39  GLY A CA  
590  C  C   . GLY A 59  ? 0.41811 0.24385 0.37955 0.03319  -0.06254 -0.00900 39  GLY A C   
591  O  O   . GLY A 59  ? 0.41610 0.23602 0.37763 0.02504  -0.06796 -0.00098 39  GLY A O   
595  N  N   . LEU A 60  ? 0.37403 0.21396 0.33393 0.03113  -0.05521 -0.01177 40  LEU A N   
596  C  CA  . LEU A 60  ? 0.36485 0.21543 0.32431 0.01990  -0.05308 -0.00617 40  LEU A CA  
597  C  C   . LEU A 60  ? 0.35946 0.22420 0.32514 0.01733  -0.05043 0.00092  40  LEU A C   
598  O  O   . LEU A 60  ? 0.35874 0.23525 0.33001 0.02340  -0.04572 -0.00071 40  LEU A O   
599  C  CB  . LEU A 60  ? 0.37516 0.23614 0.33110 0.02000  -0.04643 -0.01138 40  LEU A CB  
600  C  CG  . LEU A 60  ? 0.40806 0.28148 0.36438 0.01022  -0.04350 -0.00667 40  LEU A CG  
601  C  CD1 . LEU A 60  ? 0.47651 0.34091 0.43152 0.00034  -0.05007 -0.00188 40  LEU A CD1 
602  C  CD2 . LEU A 60  ? 0.46085 0.34217 0.41315 0.01233  -0.03786 -0.01221 40  LEU A CD2 
614  N  N   . ALA A 61  ? 0.35721 0.22064 0.32175 0.00820  -0.05367 0.00888  41  ALA A N   
615  C  CA  . ALA A 61  ? 0.33746 0.21156 0.30449 0.00548  -0.05244 0.01565  41  ALA A CA  
616  C  C   . ALA A 61  ? 0.30943 0.20135 0.27669 0.00147  -0.04513 0.01579  41  ALA A C   
617  O  O   . ALA A 61  ? 0.34074 0.23559 0.30559 -0.00314 -0.04242 0.01443  41  ALA A O   
618  C  CB  . ALA A 61  ? 0.36943 0.23437 0.33286 -0.00228 -0.05802 0.02462  41  ALA A CB  
624  N  N   . ALA A 62  ? 0.29135 0.19462 0.26192 0.00346  -0.04277 0.01728  42  ALA A N   
625  C  CA  . ALA A 62  ? 0.27879 0.19729 0.24959 0.00067  -0.03640 0.01672  42  ALA A CA  
626  C  C   . ALA A 62  ? 0.32147 0.24714 0.29271 -0.00020 -0.03743 0.02098  42  ALA A C   
627  O  O   . ALA A 62  ? 0.31610 0.24192 0.29234 0.00492  -0.04059 0.02085  42  ALA A O   
628  C  CB  . ALA A 62  ? 0.32089 0.24704 0.29610 0.00628  -0.03072 0.00985  42  ALA A CB  
634  N  N   . ALA A 63  ? 0.27492 0.20703 0.24097 -0.00614 -0.03492 0.02428  43  ALA A N   
635  C  CA  . ALA A 63  ? 0.26041 0.19891 0.22368 -0.00714 -0.03575 0.02736  43  ALA A CA  
636  C  C   . ALA A 63  ? 0.25721 0.20719 0.22571 -0.00462 -0.03148 0.02225  43  ALA A C   
637  O  O   . ALA A 63  ? 0.26444 0.22027 0.23222 -0.00650 -0.02592 0.01965  43  ALA A O   
638  C  CB  . ALA A 63  ? 0.29188 0.23142 0.24594 -0.01391 -0.03414 0.03288  43  ALA A CB  
644  N  N   . SER A 64  ? 0.26035 0.21339 0.23537 -0.00036 -0.03460 0.02110  44  SER A N   
645  C  CA  . SER A 64  ? 0.24596 0.20930 0.22897 0.00171  -0.03122 0.01678  44  SER A CA  
646  C  C   . SER A 64  ? 0.27749 0.24649 0.25764 -0.00065 -0.03318 0.01754  44  SER A C   
647  O  O   . SER A 64  ? 0.26602 0.24239 0.25111 -0.00083 -0.03005 0.01428  44  SER A O   
648  C  CB  . SER A 64  ? 0.26152 0.22687 0.25717 0.00799  -0.03282 0.01452  44  SER A CB  
649  O  OG  . SER A 64  ? 0.27136 0.23553 0.27028 0.01012  -0.04040 0.01727  44  SER A OG  
655  N  N   . THR A 65  ? 0.27167 0.23643 0.24304 -0.00237 -0.03854 0.02172  45  THR A N   
656  C  CA  . THR A 65  ? 0.27826 0.24669 0.24421 -0.00389 -0.04143 0.02162  45  THR A CA  
657  C  C   . THR A 65  ? 0.28363 0.25216 0.23620 -0.00790 -0.03684 0.02255  45  THR A C   
658  O  O   . THR A 65  ? 0.29155 0.25684 0.23847 -0.01025 -0.03346 0.02563  45  THR A O   
659  C  CB  . THR A 65  ? 0.29678 0.26054 0.25845 -0.00256 -0.05042 0.02560  45  THR A CB  
660  O  OG1 . THR A 65  ? 0.31498 0.27006 0.26615 -0.00437 -0.05087 0.03133  45  THR A OG1 
661  C  CG2 . THR A 65  ? 0.32583 0.29143 0.30303 0.00239  -0.05558 0.02453  45  THR A CG2 
669  N  N   . TYR A 66  ? 0.27475 0.24721 0.22321 -0.00853 -0.03695 0.01972  46  TYR A N   
670  C  CA  . TYR A 66  ? 0.28318 0.25625 0.21830 -0.01084 -0.03278 0.02005  46  TYR A CA  
671  C  C   . TYR A 66  ? 0.30360 0.27176 0.22516 -0.01238 -0.03445 0.02639  46  TYR A C   
672  O  O   . TYR A 66  ? 0.30710 0.27608 0.22251 -0.01486 -0.02869 0.02932  46  TYR A O   
673  C  CB  . TYR A 66  ? 0.29701 0.27226 0.22867 -0.01022 -0.03488 0.01541  46  TYR A CB  
674  C  CG  . TYR A 66  ? 0.28250 0.25896 0.20184 -0.01087 -0.02983 0.01347  46  TYR A CG  
675  C  CD1 . TYR A 66  ? 0.31896 0.29310 0.22160 -0.01106 -0.02998 0.01640  46  TYR A CD1 
676  C  CD2 . TYR A 66  ? 0.28295 0.26278 0.20731 -0.01062 -0.02482 0.00876  46  TYR A CD2 
677  C  CE1 . TYR A 66  ? 0.33107 0.30711 0.22239 -0.01036 -0.02479 0.01412  46  TYR A CE1 
678  C  CE2 . TYR A 66  ? 0.29202 0.27268 0.20574 -0.00996 -0.02050 0.00641  46  TYR A CE2 
679  C  CZ  . TYR A 66  ? 0.31933 0.29857 0.21677 -0.00951 -0.02028 0.00874  46  TYR A CZ  
680  O  OH  . TYR A 66  ? 0.34828 0.32901 0.23462 -0.00769 -0.01540 0.00621  46  TYR A OH  
690  N  N   . GLN A 67  ? 0.31233 0.27573 0.23029 -0.01105 -0.04242 0.02925  47  GLN A N   
691  C  CA  . GLN A 67  ? 0.33544 0.29296 0.23900 -0.01253 -0.04436 0.03648  47  GLN A CA  
692  C  C   . GLN A 67  ? 0.32485 0.27855 0.23160 -0.01514 -0.04111 0.04193  47  GLN A C   
693  O  O   . GLN A 67  ? 0.32309 0.27584 0.21976 -0.01853 -0.03709 0.04752  47  GLN A O   
694  C  CB  . GLN A 67  ? 0.38703 0.33915 0.28728 -0.00999 -0.05490 0.03879  47  GLN A CB  
695  C  CG  . GLN A 67  ? 0.41874 0.36398 0.30081 -0.01140 -0.05696 0.04692  47  GLN A CG  
696  C  CD  . GLN A 67  ? 0.56837 0.51598 0.43204 -0.01200 -0.05360 0.04616  47  GLN A CD  
697  O  OE1 . GLN A 67  ? 0.63734 0.58632 0.49676 -0.00967 -0.05801 0.04052  47  GLN A OE1 
698  N  NE2 . GLN A 67  ? 0.59343 0.54117 0.44568 -0.01496 -0.04628 0.05199  47  GLN A NE2 
707  N  N   . ALA A 68  ? 0.31380 0.26508 0.23448 -0.01360 -0.04290 0.04047  48  ALA A N   
708  C  CA  . ALA A 68  ? 0.30391 0.24911 0.22730 -0.01603 -0.04146 0.04474  48  ALA A CA  
709  C  C   . ALA A 68  ? 0.30574 0.25640 0.23021 -0.01980 -0.03312 0.04364  48  ALA A C   
710  O  O   . ALA A 68  ? 0.31550 0.26325 0.23684 -0.02424 -0.03104 0.04923  48  ALA A O   
711  C  CB  . ALA A 68  ? 0.30633 0.24703 0.24295 -0.01217 -0.04516 0.04189  48  ALA A CB  
717  N  N   . VAL A 69  ? 0.28792 0.24656 0.21771 -0.01837 -0.02869 0.03700  49  VAL A N   
718  C  CA  . VAL A 69  ? 0.27602 0.24038 0.20718 -0.02125 -0.02160 0.03600  49  VAL A CA  
719  C  C   . VAL A 69  ? 0.30805 0.27661 0.22807 -0.02445 -0.01749 0.04070  49  VAL A C   
720  O  O   . VAL A 69  ? 0.30260 0.27287 0.22313 -0.02868 -0.01385 0.04507  49  VAL A O   
721  C  CB  . VAL A 69  ? 0.28304 0.25408 0.22094 -0.01855 -0.01805 0.02854  49  VAL A CB  
722  C  CG1 . VAL A 69  ? 0.29621 0.27385 0.23399 -0.02081 -0.01145 0.02786  49  VAL A CG1 
723  C  CG2 . VAL A 69  ? 0.26942 0.23736 0.21825 -0.01549 -0.02012 0.02483  49  VAL A CG2 
733  N  N   . ILE A 70  ? 0.29361 0.26436 0.20370 -0.02240 -0.01792 0.03966  50  ILE A N   
734  C  CA  . ILE A 70  ? 0.33918 0.31404 0.23609 -0.02405 -0.01320 0.04372  50  ILE A CA  
735  C  C   . ILE A 70  ? 0.34125 0.31132 0.23226 -0.02824 -0.01385 0.05355  50  ILE A C   
736  O  O   . ILE A 70  ? 0.35969 0.33512 0.24805 -0.03199 -0.00747 0.05879  50  ILE A O   
737  C  CB  . ILE A 70  ? 0.38855 0.36324 0.27299 -0.02034 -0.01556 0.04037  50  ILE A CB  
738  C  CG1 . ILE A 70  ? 0.41841 0.39791 0.30777 -0.01731 -0.01354 0.03153  50  ILE A CG1 
739  C  CG2 . ILE A 70  ? 0.48961 0.46648 0.35686 -0.02118 -0.01115 0.04565  50  ILE A CG2 
740  C  CD1 . ILE A 70  ? 0.51785 0.50543 0.40908 -0.01773 -0.00494 0.03007  50  ILE A CD1 
752  N  N   . ASP A 71  ? 0.32015 0.28028 0.20983 -0.02771 -0.02161 0.05682  51  ASP A N   
753  C  CA  . ASP A 71  ? 0.35972 0.31306 0.24244 -0.03168 -0.02306 0.06700  51  ASP A CA  
754  C  C   . ASP A 71  ? 0.36167 0.31433 0.25519 -0.03721 -0.02017 0.07090  51  ASP A C   
755  O  O   . ASP A 71  ? 0.38305 0.33561 0.27198 -0.04258 -0.01697 0.07979  51  ASP A O   
756  C  CB  . ASP A 71  ? 0.39651 0.33823 0.27668 -0.02906 -0.03308 0.06938  51  ASP A CB  
757  C  CG  . ASP A 71  ? 0.43435 0.37564 0.30035 -0.02511 -0.03731 0.06846  51  ASP A CG  
758  O  OD1 . ASP A 71  ? 0.46263 0.41065 0.31697 -0.02481 -0.03200 0.06726  51  ASP A OD1 
759  O  OD2 . ASP A 71  ? 0.43161 0.36542 0.29730 -0.02183 -0.04662 0.06887  51  ASP A OD2 
764  N  N   . ALA A 72  ? 0.32907 0.28105 0.23651 -0.03621 -0.02148 0.06469  52  ALA A N   
765  C  CA  . ALA A 72  ? 0.32219 0.27286 0.23939 -0.04133 -0.02005 0.06702  52  ALA A CA  
766  C  C   . ALA A 72  ? 0.32752 0.29168 0.24697 -0.04486 -0.01146 0.06761  52  ALA A C   
767  O  O   . ALA A 72  ? 0.32052 0.28629 0.24316 -0.05139 -0.00901 0.07469  52  ALA A O   
768  C  CB  . ALA A 72  ? 0.32555 0.27136 0.25428 -0.03805 -0.02392 0.05923  52  ALA A CB  
774  N  N   . GLU A 73  ? 0.33615 0.31010 0.25485 -0.04062 -0.00711 0.06064  53  GLU A N   
775  C  CA  . GLU A 73  ? 0.32769 0.31519 0.24876 -0.04217 0.00102  0.06044  53  GLU A CA  
776  C  C   . GLU A 73  ? 0.34070 0.33391 0.25255 -0.04564 0.00663  0.06929  53  GLU A C   
777  O  O   . GLU A 73  ? 0.37475 0.37813 0.29287 -0.04987 0.01271  0.07341  53  GLU A O   
778  C  CB  . GLU A 73  ? 0.31810 0.31222 0.23722 -0.03601 0.00383  0.05169  53  GLU A CB  
779  C  CG  . GLU A 73  ? 0.31869 0.31046 0.24734 -0.03286 0.00087  0.04365  53  GLU A CG  
780  C  CD  . GLU A 73  ? 0.31956 0.31831 0.25875 -0.03461 0.00410  0.04184  53  GLU A CD  
781  O  OE1 . GLU A 73  ? 0.32481 0.32642 0.26846 -0.04009 0.00541  0.04778  53  GLU A OE1 
782  O  OE2 . GLU A 73  ? 0.30532 0.30641 0.24839 -0.03080 0.00480  0.03507  53  GLU A OE2 
789  N  N   . ARG A 74  ? 0.33100 0.31830 0.22814 -0.04389 0.00461  0.07279  54  ARG A N   
790  C  CA  . ARG A 74  ? 0.36026 0.35219 0.24481 -0.04624 0.01046  0.08151  54  ARG A CA  
791  C  C   . ARG A 74  ? 0.39124 0.37821 0.27847 -0.05420 0.00981  0.09339  54  ARG A C   
792  O  O   . ARG A 74  ? 0.43047 0.42229 0.30867 -0.05740 0.01590  0.10255  54  ARG A O   
793  C  CB  . ARG A 74  ? 0.41982 0.40603 0.28519 -0.04101 0.00751  0.08056  54  ARG A CB  
794  C  CG  . ARG A 74  ? 0.52283 0.51580 0.38246 -0.03444 0.01052  0.07096  54  ARG A CG  
795  C  CD  . ARG A 74  ? 0.61535 0.60029 0.45796 -0.02944 0.00441  0.06824  54  ARG A CD  
796  N  NE  . ARG A 74  ? 0.88554 0.87675 0.71677 -0.02407 0.00916  0.06168  54  ARG A NE  
797  C  CZ  . ARG A 74  ? 0.87407 0.85930 0.69136 -0.01908 0.00361  0.05628  54  ARG A CZ  
798  N  NH1 . ARG A 74  ? 0.81692 0.79162 0.63122 -0.01869 -0.00684 0.05695  54  ARG A NH1 
799  N  NH2 . ARG A 74  ? 0.88232 0.87197 0.68917 -0.01409 0.00796  0.04963  54  ARG A NH2 
813  N  N   . GLN A 75  ? 0.37634 0.35344 0.27546 -0.05749 0.00289  0.09361  55  GLN A N   
814  C  CA  . GLN A 75  ? 0.37680 0.34549 0.27935 -0.06534 0.00026  0.10434  55  GLN A CA  
815  C  C   . GLN A 75  ? 0.38072 0.35156 0.30210 -0.07100 -0.00040 0.10330  55  GLN A C   
816  O  O   . GLN A 75  ? 0.35514 0.31234 0.28338 -0.07288 -0.00849 0.10260  55  GLN A O   
817  C  CB  . GLN A 75  ? 0.40516 0.35512 0.30160 -0.06343 -0.00995 0.10607  55  GLN A CB  
818  C  CG  . GLN A 75  ? 0.42964 0.37644 0.30669 -0.05863 -0.01107 0.10859  55  GLN A CG  
819  C  CD  . GLN A 75  ? 0.50583 0.43498 0.37959 -0.05616 -0.02212 0.11016  55  GLN A CD  
820  O  OE1 . GLN A 75  ? 0.52512 0.45092 0.40012 -0.04937 -0.02793 0.10169  55  GLN A OE1 
821  N  NE2 . GLN A 75  ? 0.49394 0.41213 0.36424 -0.06162 -0.02498 0.12153  55  GLN A NE2 
830  N  N   . PRO A 76  ? 0.38235 0.36989 0.31231 -0.07350 0.00747  0.10311  56  PRO A N   
831  C  CA  . PRO A 76  ? 0.37276 0.36265 0.32090 -0.07862 0.00531  0.10128  56  PRO A CA  
832  C  C   . PRO A 76  ? 0.38140 0.36215 0.33708 -0.08868 0.00102  0.11138  56  PRO A C   
833  O  O   . PRO A 76  ? 0.40461 0.38031 0.37341 -0.09229 -0.00490 0.10819  56  PRO A O   
834  C  CB  . PRO A 76  ? 0.39462 0.40634 0.34982 -0.07866 0.01505  0.10041  56  PRO A CB  
835  C  CG  . PRO A 76  ? 0.40454 0.42412 0.34513 -0.07693 0.02360  0.10675  56  PRO A CG  
836  C  CD  . PRO A 76  ? 0.38765 0.39237 0.31108 -0.07096 0.01808  0.10395  56  PRO A CD  
844  N  N   . GLU A 77  ? 0.41385 0.39176 0.36122 -0.09350 0.00356  0.12351  57  GLU A N   
845  C  CA  . GLU A 77  ? 0.43655 0.40360 0.39121 -0.10379 -0.00111 0.13406  57  GLU A CA  
846  C  C   . GLU A 77  ? 0.48477 0.42750 0.43755 -0.10200 -0.01354 0.13056  57  GLU A C   
847  O  O   . GLU A 77  ? 0.49614 0.42710 0.45872 -0.10941 -0.02018 0.13447  57  GLU A O   
848  C  CB  . GLU A 77  ? 0.47456 0.44485 0.41943 -0.10915 0.00570  0.14893  57  GLU A CB  
849  C  CG  . GLU A 77  ? 0.56431 0.56008 0.51316 -0.10905 0.01912  0.15045  57  GLU A CG  
850  C  CD  . GLU A 77  ? 0.72576 0.72585 0.66628 -0.11024 0.02739  0.15997  57  GLU A CD  
851  O  OE1 . GLU A 77  ? 0.65493 0.63866 0.58877 -0.11285 0.02252  0.16677  57  GLU A OE1 
852  O  OE2 . GLU A 77  ? 0.63372 0.65338 0.57465 -0.10823 0.03897  0.16049  57  GLU A OE2 
859  N  N   . LEU A 78  ? 0.41878 0.35394 0.36027 -0.09221 -0.01707 0.12300  58  LEU A N   
860  C  CA  . LEU A 78  ? 0.41127 0.32541 0.35164 -0.08823 -0.02807 0.11836  58  LEU A CA  
861  C  C   . LEU A 78  ? 0.38015 0.29414 0.32869 -0.08219 -0.03148 0.10431  58  LEU A C   
862  O  O   . LEU A 78  ? 0.37649 0.27543 0.33077 -0.08236 -0.03962 0.10067  58  LEU A O   
863  C  CB  . LEU A 78  ? 0.43788 0.34502 0.36240 -0.08100 -0.03022 0.11940  58  LEU A CB  
864  C  CG  . LEU A 78  ? 0.47206 0.35948 0.39517 -0.07512 -0.04096 0.11522  58  LEU A CG  
865  C  CD1 . LEU A 78  ? 0.49870 0.36738 0.42693 -0.08205 -0.04829 0.12254  58  LEU A CD1 
866  C  CD2 . LEU A 78  ? 0.48151 0.36549 0.38953 -0.06865 -0.04294 0.11779  58  LEU A CD2 
878  N  N   . PHE A 79  ? 0.35673 0.28662 0.30522 -0.07694 -0.02521 0.09667  59  PHE A N   
879  C  CA  . PHE A 79  ? 0.34132 0.27345 0.29585 -0.07096 -0.02668 0.08418  59  PHE A CA  
880  C  C   . PHE A 79  ? 0.31443 0.26209 0.27933 -0.07521 -0.02143 0.08278  59  PHE A C   
881  O  O   . PHE A 79  ? 0.32172 0.28547 0.28524 -0.07260 -0.01382 0.08089  59  PHE A O   
882  C  CB  . PHE A 79  ? 0.33135 0.26847 0.27785 -0.06161 -0.02435 0.07728  59  PHE A CB  
883  C  CG  . PHE A 79  ? 0.35375 0.27734 0.29258 -0.05654 -0.03057 0.07768  59  PHE A CG  
884  C  CD1 . PHE A 79  ? 0.37467 0.28685 0.31746 -0.05120 -0.03705 0.07074  59  PHE A CD1 
885  C  CD2 . PHE A 79  ? 0.36660 0.28957 0.29401 -0.05631 -0.02993 0.08473  59  PHE A CD2 
886  C  CE1 . PHE A 79  ? 0.35128 0.25248 0.28922 -0.04585 -0.04295 0.07128  59  PHE A CE1 
887  C  CE2 . PHE A 79  ? 0.37771 0.28870 0.29903 -0.05121 -0.03688 0.08520  59  PHE A CE2 
888  C  CZ  . PHE A 79  ? 0.36635 0.26737 0.29436 -0.04585 -0.04330 0.07830  59  PHE A CZ  
898  N  N   . SER A 80  ? 0.32954 0.27157 0.30502 -0.08141 -0.02641 0.08335  60  SER A N   
899  C  CA  . SER A 80  ? 0.33405 0.29026 0.32189 -0.08738 -0.02326 0.08433  60  SER A CA  
900  C  C   . SER A 80  ? 0.31900 0.27969 0.31139 -0.08193 -0.02460 0.07275  60  SER A C   
901  O  O   . SER A 80  ? 0.32126 0.26984 0.30960 -0.07590 -0.02999 0.06448  60  SER A O   
902  C  CB  . SER A 80  ? 0.35603 0.30290 0.35338 -0.09813 -0.02938 0.09190  60  SER A CB  
903  O  OG  . SER A 80  ? 0.34610 0.30421 0.35844 -0.10444 -0.02960 0.09174  60  SER A OG  
909  N  N   . ASN A 81  ? 0.30830 0.28673 0.30946 -0.08400 -0.01960 0.07270  61  ASN A N   
910  C  CA  . ASN A 81  ? 0.30994 0.29303 0.31629 -0.08014 -0.02156 0.06338  61  ASN A CA  
911  C  C   . ASN A 81  ? 0.33129 0.31092 0.34997 -0.08765 -0.02923 0.06373  61  ASN A C   
912  O  O   . ASN A 81  ? 0.31838 0.29948 0.34028 -0.08483 -0.03277 0.05611  61  ASN A O   
913  C  CB  . ASN A 81  ? 0.30006 0.30425 0.30910 -0.07676 -0.01265 0.06238  61  ASN A CB  
914  C  CG  . ASN A 81  ? 0.29724 0.30206 0.29384 -0.06713 -0.00782 0.05690  61  ASN A CG  
915  O  OD1 . ASN A 81  ? 0.30797 0.30635 0.29473 -0.06524 -0.00663 0.05924  61  ASN A OD1 
916  N  ND2 . ASN A 81  ? 0.28981 0.30236 0.28734 -0.06134 -0.00565 0.04995  61  ASN A ND2 
923  N  N   . ALA A 82  ? 0.31568 0.29055 0.34108 -0.09746 -0.03226 0.07276  62  ALA A N   
924  C  CA  . ALA A 82  ? 0.34626 0.32076 0.38633 -0.10642 -0.03955 0.07429  62  ALA A CA  
925  C  C   . ALA A 82  ? 0.34853 0.30054 0.38520 -0.10535 -0.05180 0.06625  62  ALA A C   
926  O  O   . ALA A 82  ? 0.37539 0.32512 0.42306 -0.11218 -0.05984 0.06549  62  ALA A O   
927  C  CB  . ALA A 82  ? 0.35601 0.33371 0.40589 -0.11840 -0.03816 0.08788  62  ALA A CB  
933  N  N   . GLY A 83  ? 0.35702 0.29321 0.37937 -0.09669 -0.05365 0.05982  63  GLY A N   
934  C  CA  . GLY A 83  ? 0.36790 0.28479 0.38486 -0.09271 -0.06344 0.05019  63  GLY A CA  
935  C  C   . GLY A 83  ? 0.38427 0.30636 0.39587 -0.08351 -0.06242 0.03919  63  GLY A C   
936  O  O   . GLY A 83  ? 0.39926 0.30627 0.40426 -0.07897 -0.06962 0.03045  63  GLY A O   
940  N  N   . GLY A 84  ? 0.34729 0.28969 0.36105 -0.08067 -0.05378 0.03965  64  GLY A N   
941  C  CA  . GLY A 84  ? 0.32985 0.27735 0.33738 -0.07159 -0.05149 0.03073  64  GLY A CA  
942  C  C   . GLY A 84  ? 0.32048 0.26669 0.31659 -0.06225 -0.04479 0.02777  64  GLY A C   
943  O  O   . GLY A 84  ? 0.33022 0.26576 0.32092 -0.06085 -0.04508 0.02953  64  GLY A O   
947  N  N   . ILE A 85  ? 0.29685 0.25369 0.28997 -0.05580 -0.03940 0.02332  65  ILE A N   
948  C  CA  . ILE A 85  ? 0.26721 0.22581 0.25226 -0.04824 -0.03264 0.02144  65  ILE A CA  
949  C  C   . ILE A 85  ? 0.30583 0.25384 0.28181 -0.03990 -0.03421 0.01313  65  ILE A C   
950  O  O   . ILE A 85  ? 0.28797 0.23844 0.25916 -0.03380 -0.02885 0.01132  65  ILE A O   
951  C  CB  . ILE A 85  ? 0.26840 0.24469 0.25556 -0.04644 -0.02453 0.02304  65  ILE A CB  
952  C  CG1 . ILE A 85  ? 0.28710 0.27282 0.27881 -0.04569 -0.02496 0.01999  65  ILE A CG1 
953  C  CG2 . ILE A 85  ? 0.29212 0.27800 0.28472 -0.05259 -0.02048 0.03172  65  ILE A CG2 
954  C  CD1 . ILE A 85  ? 0.30940 0.28854 0.29347 -0.03881 -0.02673 0.01242  65  ILE A CD1 
966  N  N   . ARG A 86  ? 0.30658 0.24221 0.27987 -0.03949 -0.04147 0.00825  66  ARG A N   
967  C  CA  . ARG A 86  ? 0.31704 0.24120 0.28037 -0.03104 -0.04253 0.00056  66  ARG A CA  
968  C  C   . ARG A 86  ? 0.37645 0.28262 0.33679 -0.03048 -0.04851 -0.00069 66  ARG A C   
969  O  O   . ARG A 86  ? 0.40640 0.30578 0.37173 -0.03775 -0.05447 0.00338  66  ARG A O   
970  C  CB  . ARG A 86  ? 0.32085 0.24332 0.27936 -0.02853 -0.04604 -0.00573 66  ARG A CB  
971  C  CG  . ARG A 86  ? 0.32360 0.26177 0.28399 -0.02754 -0.04106 -0.00514 66  ARG A CG  
972  C  CD  . ARG A 86  ? 0.31255 0.26035 0.27217 -0.02315 -0.03157 -0.00334 66  ARG A CD  
973  N  NE  . ARG A 86  ? 0.29164 0.23188 0.24313 -0.01562 -0.02867 -0.00758 66  ARG A NE  
974  C  CZ  . ARG A 86  ? 0.31812 0.26016 0.27086 -0.01332 -0.02382 -0.00569 66  ARG A CZ  
975  N  NH1 . ARG A 86  ? 0.29145 0.23952 0.25027 -0.01770 -0.02219 -0.00011 66  ARG A NH1 
976  N  NH2 . ARG A 86  ? 0.31220 0.25056 0.25993 -0.00628 -0.02048 -0.00936 66  ARG A NH2 
990  N  N   . PRO A 87  ? 0.37933 0.27721 0.33222 -0.02179 -0.04713 -0.00609 67  PRO A N   
991  C  CA  . PRO A 87  ? 0.44555 0.32719 0.39673 -0.02005 -0.05207 -0.00663 67  PRO A CA  
992  C  C   . PRO A 87  ? 0.52581 0.38976 0.47344 -0.02189 -0.06200 -0.01106 67  PRO A C   
993  O  O   . PRO A 87  ? 0.56201 0.41189 0.51107 -0.02440 -0.06807 -0.00897 67  PRO A O   
994  C  CB  . PRO A 87  ? 0.48424 0.36567 0.43030 -0.00921 -0.04657 -0.01147 67  PRO A CB  
995  C  CG  . PRO A 87  ? 0.42179 0.31439 0.36393 -0.00549 -0.04061 -0.01522 67  PRO A CG  
996  C  CD  . PRO A 87  ? 0.37101 0.27645 0.31904 -0.01347 -0.03955 -0.00999 67  PRO A CD  
1004 N  N   . ASP A 88  ? 0.48651 0.34966 0.42914 -0.02095 -0.06471 -0.01690 68  ASP A N   
1005 C  CA  . ASP A 88  ? 0.60254 0.44648 0.53833 -0.02034 -0.07484 -0.02374 68  ASP A CA  
1006 C  C   . ASP A 88  ? 0.55180 0.39866 0.49134 -0.02851 -0.08169 -0.02361 68  ASP A C   
1007 O  O   . ASP A 88  ? 0.58552 0.42024 0.51651 -0.02639 -0.08938 -0.03129 68  ASP A O   
1008 C  CB  . ASP A 88  ? 0.71393 0.55046 0.63550 -0.00797 -0.07253 -0.03362 68  ASP A CB  
1009 C  CG  . ASP A 88  ? 0.95923 0.81259 0.87702 -0.00367 -0.06383 -0.03470 68  ASP A CG  
1010 O  OD1 . ASP A 88  ? 0.72611 0.59671 0.65283 -0.00917 -0.05908 -0.02811 68  ASP A OD1 
1011 O  OD2 . ASP A 88  ? 1.08786 0.93646 0.99296 0.00544  -0.06173 -0.04206 68  ASP A OD2 
1016 N  N   . GLN A 89  ? 0.46972 0.33312 0.42180 -0.03726 -0.07912 -0.01531 69  GLN A N   
1017 C  CA  . GLN A 89  ? 0.47281 0.34389 0.43202 -0.04477 -0.08454 -0.01423 69  GLN A CA  
1018 C  C   . GLN A 89  ? 0.43298 0.31222 0.40848 -0.05680 -0.08549 -0.00386 69  GLN A C   
1019 O  O   . GLN A 89  ? 0.42516 0.31213 0.40493 -0.05799 -0.07796 0.00322  69  GLN A O   
1020 C  CB  . GLN A 89  ? 0.50300 0.39217 0.46074 -0.04051 -0.07743 -0.01520 69  GLN A CB  
1021 C  CG  . GLN A 89  ? 0.54189 0.42419 0.48289 -0.02884 -0.07506 -0.02409 69  GLN A CG  
1022 C  CD  . GLN A 89  ? 0.55580 0.45432 0.49468 -0.02431 -0.06697 -0.02369 69  GLN A CD  
1023 O  OE1 . GLN A 89  ? 0.55376 0.46772 0.50297 -0.02932 -0.06518 -0.01853 69  GLN A OE1 
1024 N  NE2 . GLN A 89  ? 0.58718 0.48221 0.51296 -0.01445 -0.06155 -0.02880 69  GLN A NE2 
1033 N  N   . PRO A 90  ? 0.45490 0.33287 0.43957 -0.06591 -0.09472 -0.00253 70  PRO A N   
1034 C  CA  . PRO A 90  ? 0.44449 0.33160 0.44631 -0.07822 -0.09509 0.00833  70  PRO A CA  
1035 C  C   . PRO A 90  ? 0.43417 0.34828 0.44650 -0.08021 -0.08616 0.01416  70  PRO A C   
1036 O  O   . PRO A 90  ? 0.42930 0.35340 0.43675 -0.07317 -0.08196 0.00957  70  PRO A O   
1037 C  CB  . PRO A 90  ? 0.51661 0.39254 0.52519 -0.08674 -0.10927 0.00629  70  PRO A CB  
1038 C  CG  . PRO A 90  ? 0.55850 0.42994 0.55532 -0.07883 -0.11441 -0.00512 70  PRO A CG  
1039 C  CD  . PRO A 90  ? 0.47315 0.33867 0.45205 -0.06539 -0.10639 -0.01123 70  PRO A CD  
1047 N  N   . ALA A 91  ? 0.43613 0.36131 0.46272 -0.08973 -0.08320 0.02469  71  ALA A N   
1048 C  CA  . ALA A 91  ? 0.39474 0.34578 0.43214 -0.09150 -0.07409 0.03074  71  ALA A CA  
1049 C  C   . ALA A 91  ? 0.37505 0.33820 0.42234 -0.09341 -0.07921 0.02784  71  ALA A C   
1050 O  O   . ALA A 91  ? 0.43006 0.38483 0.48336 -0.09952 -0.09106 0.02565  71  ALA A O   
1051 C  CB  . ALA A 91  ? 0.42323 0.38296 0.47349 -0.10168 -0.06992 0.04310  71  ALA A CB  
1057 N  N   . LEU A 92  ? 0.39674 0.37944 0.44636 -0.08837 -0.07088 0.02816  72  LEU A N   
1058 C  CA  . LEU A 92  ? 0.40283 0.40243 0.46509 -0.08992 -0.07371 0.02777  72  LEU A CA  
1059 C  C   . LEU A 92  ? 0.42890 0.45225 0.51010 -0.09638 -0.06593 0.03796  72  LEU A C   
1060 O  O   . LEU A 92  ? 0.35072 0.37911 0.42989 -0.09606 -0.05567 0.04375  72  LEU A O   
1061 C  CB  . LEU A 92  ? 0.44642 0.45070 0.49748 -0.07835 -0.06970 0.02087  72  LEU A CB  
1062 C  CG  . LEU A 92  ? 0.47742 0.46170 0.50830 -0.07008 -0.07477 0.01092  72  LEU A CG  
1063 C  CD1 . LEU A 92  ? 0.55903 0.55059 0.58133 -0.06019 -0.06965 0.00670  72  LEU A CD1 
1064 C  CD2 . LEU A 92  ? 0.60692 0.57870 0.63886 -0.07466 -0.08957 0.00621  72  LEU A CD2 
1076 N  N   . PRO A 93  ? 0.36644 0.40577 0.46566 -0.10135 -0.07009 0.04016  73  PRO A N   
1077 C  CA  . PRO A 93  ? 0.39881 0.46336 0.51832 -0.10728 -0.06184 0.05026  73  PRO A CA  
1078 C  C   . PRO A 93  ? 0.37858 0.46159 0.49636 -0.09760 -0.04999 0.04974  73  PRO A C   
1079 O  O   . PRO A 93  ? 0.35381 0.45629 0.48570 -0.09619 -0.04952 0.05026  73  PRO A O   
1080 C  CB  . PRO A 93  ? 0.39320 0.46659 0.53423 -0.11615 -0.07319 0.05169  73  PRO A CB  
1081 C  CG  . PRO A 93  ? 0.39484 0.45483 0.52415 -0.10981 -0.08426 0.04068  73  PRO A CG  
1082 C  CD  . PRO A 93  ? 0.41284 0.44720 0.51595 -0.10284 -0.08403 0.03390  73  PRO A CD  
1090 N  N   . MET A 94  ? 0.33284 0.40948 0.43368 -0.09062 -0.04077 0.04868  74  MET A N   
1091 C  CA  . MET A 94  ? 0.28778 0.37773 0.38403 -0.08121 -0.02972 0.04760  74  MET A CA  
1092 C  C   . MET A 94  ? 0.26489 0.35397 0.35212 -0.08051 -0.01908 0.05242  74  MET A C   
1093 O  O   . MET A 94  ? 0.29894 0.37359 0.37954 -0.08522 -0.02099 0.05509  74  MET A O   
1094 C  CB  . MET A 94  ? 0.38302 0.46323 0.46429 -0.07070 -0.03246 0.03787  74  MET A CB  
1095 C  CG  . MET A 94  ? 0.47758 0.53367 0.54311 -0.06931 -0.04023 0.03156  74  MET A CG  
1096 S  SD  . MET A 94  ? 0.42861 0.47509 0.47385 -0.05631 -0.03752 0.02277  74  MET A SD  
1097 C  CE  . MET A 94  ? 0.44714 0.49372 0.49346 -0.05330 -0.04729 0.01709  74  MET A CE  
1107 N  N   . MET A 95  ? 0.26000 0.36457 0.34698 -0.07414 -0.00844 0.05339  75  MET A N   
1108 C  CA  A MET A 95  ? 0.26726 0.37440 0.34567 -0.07273 0.00222  0.05799  75  MET A CA  
1109 C  CA  B MET A 95  ? 0.26530 0.37250 0.34432 -0.07336 0.00206  0.05843  75  MET A CA  
1110 C  C   . MET A 95  ? 0.27911 0.36436 0.33859 -0.07108 0.00040  0.05544  75  MET A C   
1111 O  O   . MET A 95  ? 0.27658 0.35750 0.33089 -0.07496 0.00376  0.06139  75  MET A O   
1112 C  CB  A MET A 95  ? 0.29414 0.41343 0.36871 -0.06257 0.01081  0.05444  75  MET A CB  
1113 C  CB  B MET A 95  ? 0.29200 0.41532 0.36993 -0.06471 0.01244  0.05720  75  MET A CB  
1114 C  CG  A MET A 95  ? 0.29551 0.42975 0.37029 -0.06085 0.02282  0.05979  75  MET A CG  
1115 C  CG  B MET A 95  ? 0.27799 0.39220 0.33992 -0.05406 0.01371  0.04873  75  MET A CG  
1116 S  SD  A MET A 95  ? 0.24440 0.37942 0.30601 -0.04680 0.02875  0.05124  75  MET A SD  
1117 S  SD  B MET A 95  ? 0.24004 0.36947 0.29785 -0.04501 0.02655  0.04843  75  MET A SD  
1118 C  CE  A MET A 95  ? 0.25878 0.41063 0.33888 -0.04306 0.02615  0.04857  75  MET A CE  
1119 C  CE  B MET A 95  ? 0.25840 0.40921 0.33801 -0.04329 0.02572  0.04846  75  MET A CE  
1136 N  N   . ILE A 96  ? 0.24413 0.31623 0.29307 -0.06475 -0.00450 0.04695  76  ILE A N   
1137 C  CA  . ILE A 96  ? 0.26775 0.32254 0.30008 -0.06113 -0.00476 0.04389  76  ILE A CA  
1138 C  C   . ILE A 96  ? 0.27183 0.31104 0.30304 -0.06784 -0.01176 0.04649  76  ILE A C   
1139 O  O   . ILE A 96  ? 0.28764 0.31438 0.30756 -0.06609 -0.01145 0.04640  76  ILE A O   
1140 C  CB  . ILE A 96  ? 0.22522 0.27267 0.24822 -0.05243 -0.00668 0.03488  76  ILE A CB  
1141 C  CG1 . ILE A 96  ? 0.25882 0.29490 0.26717 -0.04739 -0.00388 0.03233  76  ILE A CG1 
1142 C  CG2 . ILE A 96  ? 0.26004 0.29682 0.28370 -0.05338 -0.01633 0.03017  76  ILE A CG2 
1143 C  CD1 . ILE A 96  ? 0.26140 0.29370 0.26187 -0.03896 -0.00318 0.02498  76  ILE A CD1 
1155 N  N   . ASP A 97  ? 0.27590 0.31480 0.31896 -0.07546 -0.01876 0.04883  77  ASP A N   
1156 C  CA  . ASP A 97  ? 0.30183 0.32427 0.34476 -0.08242 -0.02639 0.05147  77  ASP A CA  
1157 C  C   . ASP A 97  ? 0.30923 0.33935 0.36401 -0.09300 -0.02430 0.06278  77  ASP A C   
1158 O  O   . ASP A 97  ? 0.33375 0.35416 0.39548 -0.10146 -0.03222 0.06607  77  ASP A O   
1159 C  CB  . ASP A 97  ? 0.33607 0.34818 0.38213 -0.08387 -0.03780 0.04521  77  ASP A CB  
1160 C  CG  . ASP A 97  ? 0.35658 0.35597 0.38798 -0.07419 -0.04041 0.03504  77  ASP A CG  
1161 O  OD1 . ASP A 97  ? 0.33510 0.33120 0.35505 -0.06730 -0.03453 0.03303  77  ASP A OD1 
1162 O  OD2 . ASP A 97  ? 0.38704 0.37966 0.41818 -0.07349 -0.04866 0.02904  77  ASP A OD2 
1167 N  N   . MET A 98  ? 0.29882 0.34603 0.35577 -0.09263 -0.01361 0.06890  78  MET A N   
1168 C  CA  . MET A 98  ? 0.29255 0.35000 0.35949 -0.10182 -0.00882 0.08075  78  MET A CA  
1169 C  C   . MET A 98  ? 0.28747 0.34418 0.34050 -0.09920 0.00007  0.08602  78  MET A C   
1170 O  O   . MET A 98  ? 0.28823 0.34473 0.32785 -0.08977 0.00478  0.08048  78  MET A O   
1171 C  CB  . MET A 98  ? 0.34068 0.42424 0.42576 -0.10405 -0.00315 0.08429  78  MET A CB  
1172 C  CG  . MET A 98  ? 0.34656 0.43317 0.44706 -0.10721 -0.01282 0.07996  78  MET A CG  
1173 S  SD  . MET A 98  ? 0.35678 0.47507 0.47821 -0.10582 -0.00698 0.08136  78  MET A SD  
1174 C  CE  . MET A 98  ? 0.38178 0.51751 0.51981 -0.11750 0.00140  0.09681  78  MET A CE  
1184 N  N   . ASP A 99  ? 0.33249 0.38820 0.38874 -0.10810 0.00167  0.09717  79  ASP A N   
1185 C  CA  . ASP A 99  ? 0.31983 0.37751 0.36362 -0.10707 0.01057  0.10456  79  ASP A CA  
1186 C  C   . ASP A 99  ? 0.30461 0.38711 0.35892 -0.11091 0.02201  0.11367  79  ASP A C   
1187 O  O   . ASP A 99  ? 0.30982 0.40649 0.38483 -0.11778 0.02170  0.11738  79  ASP A O   
1188 C  CB  . ASP A 99  ? 0.38168 0.41949 0.41868 -0.11354 0.00512  0.11195  79  ASP A CB  
1189 C  CG  . ASP A 99  ? 0.33005 0.34329 0.35628 -0.10866 -0.00538 0.10340  79  ASP A CG  
1190 O  OD1 . ASP A 99  ? 0.31482 0.32652 0.33178 -0.09849 -0.00506 0.09318  79  ASP A OD1 
1191 O  OD2 . ASP A 99  ? 0.37199 0.36723 0.39870 -0.11477 -0.01344 0.10749  79  ASP A OD2 
1196 N  N   . ASP A 100 ? 0.37854 0.46642 0.41835 -0.10628 0.03199  0.11739  80  ASP A N   
1197 C  CA  . ASP A 100 ? 0.35988 0.46981 0.40594 -0.10951 0.04442  0.12749  80  ASP A CA  
1198 C  C   . ASP A 100 ? 0.40044 0.50647 0.45561 -0.12065 0.04298  0.13877  80  ASP A C   
1199 O  O   . ASP A 100 ? 0.41234 0.49695 0.46072 -0.12526 0.03476  0.14161  80  ASP A O   
1200 C  CB  . ASP A 100 ? 0.36824 0.47993 0.39177 -0.10079 0.05402  0.12741  80  ASP A CB  
1201 C  CG  . ASP A 100 ? 0.40597 0.52273 0.42229 -0.08809 0.05644  0.11452  80  ASP A CG  
1202 O  OD1 . ASP A 100 ? 0.35233 0.47758 0.38291 -0.08601 0.05417  0.10795  80  ASP A OD1 
1203 O  OD2 . ASP A 100 ? 0.50098 0.61320 0.49710 -0.08007 0.06038  0.11106  80  ASP A OD2 
1208 N  N   . PRO A 101 ? 0.39532 0.52027 0.46608 -0.12374 0.05038  0.14385  81  PRO A N   
1209 C  CA  . PRO A 101 ? 0.34025 0.49038 0.41884 -0.11704 0.06076  0.14067  81  PRO A CA  
1210 C  C   . PRO A 101 ? 0.41193 0.57489 0.51203 -0.11744 0.05563  0.13466  81  PRO A C   
1211 O  O   . PRO A 101 ? 0.35115 0.53281 0.45534 -0.10963 0.06325  0.13043  81  PRO A O   
1212 C  CB  . PRO A 101 ? 0.40960 0.57249 0.49638 -0.12133 0.07018  0.14994  81  PRO A CB  
1213 C  CG  . PRO A 101 ? 0.41187 0.56138 0.50988 -0.13364 0.06029  0.15642  81  PRO A CG  
1214 C  CD  . PRO A 101 ? 0.41442 0.53694 0.49598 -0.13378 0.04944  0.15345  81  PRO A CD  
1222 N  N   . ALA A 102 ? 0.35464 0.50689 0.46714 -0.12554 0.04265  0.13377  82  ALA A N   
1223 C  CA  . ALA A 102 ? 0.36038 0.52437 0.49290 -0.12612 0.03658  0.12815  82  ALA A CA  
1224 C  C   . ALA A 102 ? 0.33424 0.49901 0.45603 -0.11389 0.03709  0.11670  82  ALA A C   
1225 O  O   . ALA A 102 ? 0.30645 0.48890 0.44058 -0.10878 0.03915  0.11220  82  ALA A O   
1226 C  CB  . ALA A 102 ? 0.33265 0.47951 0.47475 -0.13549 0.02081  0.12694  82  ALA A CB  
1232 N  N   . HIS A 103 ? 0.29155 0.43439 0.38951 -0.10739 0.03413  0.11018  83  HIS A N   
1233 C  CA  . HIS A 103 ? 0.25204 0.39106 0.33736 -0.09459 0.03398  0.09785  83  HIS A CA  
1234 C  C   . HIS A 103 ? 0.28204 0.44147 0.36565 -0.08600 0.04687  0.09731  83  HIS A C   
1235 O  O   . HIS A 103 ? 0.28446 0.45064 0.37028 -0.07746 0.04708  0.08901  83  HIS A O   
1236 C  CB  . HIS A 103 ? 0.28292 0.39784 0.34466 -0.09003 0.03032  0.09309  83  HIS A CB  
1237 C  CG  . HIS A 103 ? 0.27016 0.38378 0.31712 -0.07760 0.03393  0.08352  83  HIS A CG  
1238 N  ND1 . HIS A 103 ? 0.29595 0.41447 0.32903 -0.07174 0.04356  0.08466  83  HIS A ND1 
1239 C  CD2 . HIS A 103 ? 0.27053 0.37771 0.31401 -0.07023 0.02894  0.07290  83  HIS A CD2 
1240 C  CE1 . HIS A 103 ? 0.29363 0.40798 0.31633 -0.06172 0.04358  0.07482  83  HIS A CE1 
1241 N  NE2 . HIS A 103 ? 0.28176 0.39006 0.31123 -0.06080 0.03537  0.06816  83  HIS A NE2 
1250 N  N   . LEU A 104 ? 0.29623 0.46350 0.37321 -0.08716 0.05757  0.10568  84  LEU A N   
1251 C  CA  . LEU A 104 ? 0.36515 0.54947 0.43669 -0.07759 0.07018  0.10416  84  LEU A CA  
1252 C  C   . LEU A 104 ? 0.32300 0.53354 0.41893 -0.07671 0.07463  0.10497  84  LEU A C   
1253 O  O   . LEU A 104 ? 0.31999 0.54002 0.41437 -0.06580 0.07943  0.09776  84  LEU A O   
1254 C  CB  . LEU A 104 ? 0.43805 0.62544 0.49712 -0.07927 0.08066  0.11345  84  LEU A CB  
1255 C  CG  . LEU A 104 ? 0.43610 0.63218 0.48083 -0.06687 0.09225  0.10870  84  LEU A CG  
1256 C  CD1 . LEU A 104 ? 0.50896 0.69493 0.53760 -0.05653 0.08921  0.09728  84  LEU A CD1 
1257 C  CD2 . LEU A 104 ? 0.51627 0.70527 0.54291 -0.06731 0.09889  0.11464  84  LEU A CD2 
1269 N  N   . LEU A 105 ? 0.28061 0.50157 0.39926 -0.08754 0.07235  0.11312  85  LEU A N   
1270 C  CA  . LEU A 105 ? 0.26207 0.50581 0.40553 -0.08636 0.07423  0.11270  85  LEU A CA  
1271 C  C   . LEU A 105 ? 0.26824 0.51240 0.41919 -0.08152 0.06512  0.10346  85  LEU A C   
1272 O  O   . LEU A 105 ? 0.25542 0.51582 0.41445 -0.07252 0.06932  0.09885  85  LEU A O   
1273 C  CB  . LEU A 105 ? 0.30378 0.55171 0.46796 -0.09880 0.07022  0.12091  85  LEU A CB  
1274 C  CG  . LEU A 105 ? 0.30716 0.57801 0.49938 -0.09863 0.06942  0.12018  85  LEU A CG  
1275 C  CD1 . LEU A 105 ? 0.36095 0.65219 0.55428 -0.08796 0.08366  0.11908  85  LEU A CD1 
1276 C  CD2 . LEU A 105 ? 0.32701 0.59984 0.53943 -0.11206 0.06395  0.12805  85  LEU A CD2 
1288 N  N   . ARG A 106 ? 0.27372 0.49491 0.41879 -0.08544 0.05148  0.09864  86  ARG A N   
1289 C  CA  . ARG A 106 ? 0.24167 0.45625 0.38811 -0.07942 0.04145  0.08804  86  ARG A CA  
1290 C  C   . ARG A 106 ? 0.27381 0.48397 0.40201 -0.06519 0.04635  0.07881  86  ARG A C   
1291 O  O   . ARG A 106 ? 0.24720 0.46593 0.38203 -0.05742 0.04526  0.07294  86  ARG A O   
1292 C  CB  . ARG A 106 ? 0.27467 0.46340 0.41345 -0.08522 0.02752  0.08445  86  ARG A CB  
1293 C  CG  . ARG A 106 ? 0.25684 0.43803 0.39612 -0.08016 0.01672  0.07458  86  ARG A CG  
1294 C  CD  . ARG A 106 ? 0.27873 0.47807 0.44475 -0.08481 0.01054  0.07650  86  ARG A CD  
1295 N  NE  . ARG A 106 ? 0.30855 0.50638 0.48943 -0.09892 0.00320  0.08359  86  ARG A NE  
1296 C  CZ  . ARG A 106 ? 0.33414 0.51145 0.51133 -0.10447 -0.01045 0.07995  86  ARG A CZ  
1297 N  NH1 . ARG A 106 ? 0.33549 0.49487 0.49640 -0.09705 -0.01802 0.06959  86  ARG A NH1 
1298 N  NH2 . ARG A 106 ? 0.42753 0.60141 0.61690 -0.11770 -0.01636 0.08706  86  ARG A NH2 
1312 N  N   . ARG A 107 ? 0.25293 0.44895 0.35820 -0.06175 0.05100  0.07762  87  ARG A N   
1313 C  CA  . ARG A 107 ? 0.23763 0.42739 0.32528 -0.04921 0.05470  0.06884  87  ARG A CA  
1314 C  C   . ARG A 107 ? 0.25597 0.46794 0.34993 -0.04100 0.06612  0.06905  87  ARG A C   
1315 O  O   . ARG A 107 ? 0.27513 0.48767 0.36616 -0.03073 0.06624  0.06119  87  ARG A O   
1316 C  CB  . ARG A 107 ? 0.24624 0.41747 0.30948 -0.04798 0.05655  0.06802  87  ARG A CB  
1317 C  CG  . ARG A 107 ? 0.30536 0.46857 0.35154 -0.03608 0.05867  0.05858  87  ARG A CG  
1318 C  CD  . ARG A 107 ? 0.38712 0.53094 0.41147 -0.03542 0.05738  0.05683  87  ARG A CD  
1319 N  NE  . ARG A 107 ? 0.33764 0.47460 0.34677 -0.02503 0.05947  0.04843  87  ARG A NE  
1320 C  CZ  . ARG A 107 ? 0.32036 0.43900 0.31751 -0.02246 0.05310  0.04211  87  ARG A CZ  
1321 N  NH1 . ARG A 107 ? 0.28189 0.38766 0.27989 -0.02809 0.04478  0.04243  87  ARG A NH1 
1322 N  NH2 . ARG A 107 ? 0.33696 0.45018 0.32163 -0.01386 0.05516  0.03521  87  ARG A NH2 
1336 N  N   . LYS A 108 ? 0.25386 0.48356 0.35567 -0.04494 0.07618  0.07816  88  LYS A N   
1337 C  CA  . LYS A 108 ? 0.26787 0.52042 0.37625 -0.03640 0.08832  0.07856  88  LYS A CA  
1338 C  C   . LYS A 108 ? 0.30280 0.57200 0.43497 -0.03315 0.08476  0.07590  88  LYS A C   
1339 O  O   . LYS A 108 ? 0.27240 0.55131 0.40522 -0.02132 0.09005  0.07034  88  LYS A O   
1340 C  CB  . LYS A 108 ? 0.34330 0.61055 0.45697 -0.04210 0.09908  0.08919  88  LYS A CB  
1341 C  CG  . LYS A 108 ? 0.45029 0.70212 0.53639 -0.04085 0.10470  0.09034  88  LYS A CG  
1342 C  CD  . LYS A 108 ? 0.49310 0.75419 0.58261 -0.04460 0.11403  0.09833  88  LYS A CD  
1343 C  CE  . LYS A 108 ? 0.61252 0.86136 0.67347 -0.04014 0.12111  0.09816  88  LYS A CE  
1344 N  NZ  . LYS A 108 ? 0.67709 0.92680 0.73878 -0.04942 0.12575  0.10901  88  LYS A NZ  
1358 N  N   . LEU A 109 ? 0.24756 0.52031 0.39979 -0.04341 0.07538  0.07999  89  LEU A N   
1359 C  CA  . LEU A 109 ? 0.20488 0.49364 0.38063 -0.04105 0.07013  0.07795  89  LEU A CA  
1360 C  C   . LEU A 109 ? 0.21867 0.49168 0.38229 -0.03078 0.06227  0.06654  89  LEU A C   
1361 O  O   . LEU A 109 ? 0.24801 0.53336 0.42019 -0.02100 0.06395  0.06253  89  LEU A O   
1362 C  CB  . LEU A 109 ? 0.20146 0.49337 0.39849 -0.05500 0.05947  0.08396  89  LEU A CB  
1363 C  CG  . LEU A 109 ? 0.21400 0.52615 0.43171 -0.06505 0.06609  0.09553  89  LEU A CG  
1364 C  CD1 . LEU A 109 ? 0.27857 0.58299 0.50942 -0.08009 0.05355  0.10038  89  LEU A CD1 
1365 C  CD2 . LEU A 109 ? 0.21301 0.54955 0.45135 -0.05830 0.07169  0.09503  89  LEU A CD2 
1377 N  N   . VAL A 110 ? 0.21048 0.45659 0.35533 -0.03295 0.05352  0.06180  90  VAL A N   
1378 C  CA  . VAL A 110 ? 0.20579 0.43600 0.33843 -0.02429 0.04645  0.05214  90  VAL A CA  
1379 C  C   . VAL A 110 ? 0.26162 0.48777 0.37711 -0.01209 0.05501  0.04649  90  VAL A C   
1380 O  O   . VAL A 110 ? 0.25063 0.47222 0.36257 -0.00285 0.05216  0.03980  90  VAL A O   
1381 C  CB  . VAL A 110 ? 0.20120 0.40547 0.31930 -0.02999 0.03614  0.04924  90  VAL A CB  
1382 C  CG1 . VAL A 110 ? 0.24929 0.43708 0.35326 -0.02128 0.03045  0.04029  90  VAL A CG1 
1383 C  CG2 . VAL A 110 ? 0.23321 0.43940 0.36741 -0.04138 0.02635  0.05357  90  VAL A CG2 
1393 N  N   . ASN A 111 ? 0.26158 0.48885 0.36593 -0.01175 0.06510  0.04920  91  ASN A N   
1394 C  CA  . ASN A 111 ? 0.31185 0.53322 0.39805 -0.00038 0.07223  0.04306  91  ASN A CA  
1395 C  C   . ASN A 111 ? 0.29414 0.53207 0.39091 0.01104  0.07732  0.03968  91  ASN A C   
1396 O  O   . ASN A 111 ? 0.33659 0.56553 0.41904 0.02170  0.07978  0.03244  91  ASN A O   
1397 C  CB  . ASN A 111 ? 0.35470 0.57768 0.42811 -0.00196 0.08239  0.04738  91  ASN A CB  
1398 C  CG  . ASN A 111 ? 0.44438 0.65673 0.49539 0.00890  0.08760  0.04007  91  ASN A CG  
1399 O  OD1 . ASN A 111 ? 0.41665 0.60725 0.44994 0.00943  0.08207  0.03504  91  ASN A OD1 
1400 N  ND2 . ASN A 111 ? 0.43989 0.66799 0.49243 0.01797  0.09812  0.03913  91  ASN A ND2 
1407 N  N   . ALA A 112 ? 0.26973 0.53145 0.39192 0.00927  0.07857  0.04468  92  ALA A N   
1408 C  CA  . ALA A 112 ? 0.29583 0.57450 0.43001 0.02113  0.08311  0.04153  92  ALA A CA  
1409 C  C   . ALA A 112 ? 0.30529 0.56758 0.43187 0.02966  0.07419  0.03287  92  ALA A C   
1410 O  O   . ALA A 112 ? 0.35460 0.62083 0.48033 0.04234  0.07821  0.02774  92  ALA A O   
1411 C  CB  . ALA A 112 ? 0.32001 0.62705 0.48637 0.01646  0.08312  0.04868  92  ALA A CB  
1417 N  N   . GLY A 113 ? 0.28283 0.52630 0.40338 0.02330  0.06237  0.03137  93  GLY A N   
1418 C  CA  . GLY A 113 ? 0.29413 0.52098 0.40589 0.03041  0.05428  0.02445  93  GLY A CA  
1419 C  C   . GLY A 113 ? 0.29904 0.50242 0.38504 0.03543  0.05578  0.01823  93  GLY A C   
1420 O  O   . GLY A 113 ? 0.32873 0.51763 0.40679 0.04150  0.05015  0.01302  93  GLY A O   
1424 N  N   . PHE A 114 ? 0.29502 0.49393 0.36787 0.03260  0.06266  0.01913  94  PHE A N   
1425 C  CA  . PHE A 114 ? 0.30125 0.47692 0.35044 0.03485  0.06203  0.01373  94  PHE A CA  
1426 C  C   . PHE A 114 ? 0.30970 0.48741 0.34649 0.04049  0.07220  0.01186  94  PHE A C   
1427 O  O   . PHE A 114 ? 0.33336 0.49548 0.35168 0.03853  0.07236  0.00987  94  PHE A O   
1428 C  CB  . PHE A 114 ? 0.31638 0.47708 0.35761 0.02404  0.05576  0.01595  94  PHE A CB  
1429 C  CG  . PHE A 114 ? 0.30436 0.45890 0.35227 0.02024  0.04567  0.01598  94  PHE A CG  
1430 C  CD1 . PHE A 114 ? 0.32343 0.45979 0.36043 0.02382  0.03993  0.01098  94  PHE A CD1 
1431 C  CD2 . PHE A 114 ? 0.35738 0.52462 0.42274 0.01321  0.04169  0.02115  94  PHE A CD2 
1432 C  CE1 . PHE A 114 ? 0.46156 0.59239 0.50265 0.02126  0.03111  0.01109  94  PHE A CE1 
1433 C  CE2 . PHE A 114 ? 0.36585 0.52643 0.43510 0.01062  0.03165  0.02032  94  PHE A CE2 
1434 C  CZ  . PHE A 114 ? 0.40202 0.54465 0.45825 0.01507  0.02677  0.01531  94  PHE A CZ  
1444 N  N   . THR A 115 ? 0.30470 0.50165 0.35098 0.04811  0.08057  0.01221  95  THR A N   
1445 C  CA  . THR A 115 ? 0.35819 0.55577 0.38983 0.05593  0.09042  0.00889  95  THR A CA  
1446 C  C   . THR A 115 ? 0.37332 0.54796 0.38617 0.06441  0.08660  -0.00061 95  THR A C   
1447 O  O   . THR A 115 ? 0.35819 0.52191 0.37371 0.06660  0.07854  -0.00396 95  THR A O   
1448 C  CB  . THR A 115 ? 0.36565 0.58860 0.41177 0.06430  0.10047  0.01028  95  THR A CB  
1449 O  OG1 . THR A 115 ? 0.36300 0.58763 0.41959 0.07360  0.09647  0.00561  95  THR A OG1 
1450 C  CG2 . THR A 115 ? 0.42608 0.67310 0.49396 0.05448  0.10398  0.02073  95  THR A CG2 
1458 N  N   . ARG A 116 ? 0.38619 0.55236 0.37904 0.06857  0.09186  -0.00460 96  ARG A N   
1459 C  CA  . ARG A 116 ? 0.38378 0.52650 0.35864 0.07519  0.08717  -0.01364 96  ARG A CA  
1460 C  C   . ARG A 116 ? 0.39701 0.54061 0.37863 0.08725  0.08685  -0.01926 96  ARG A C   
1461 O  O   . ARG A 116 ? 0.38302 0.50822 0.36035 0.08943  0.07886  -0.02386 96  ARG A O   
1462 C  CB  . ARG A 116 ? 0.45544 0.59005 0.40747 0.07860  0.09241  -0.01764 96  ARG A CB  
1465 N  N   . LYS A 117 ? 0.41407 0.57978 0.40795 0.09501  0.09545  -0.01812 97  LYS A N   
1466 C  CA  . LYS A 117 ? 0.39047 0.55870 0.39242 0.10784  0.09534  -0.02324 97  LYS A CA  
1467 C  C   . LYS A 117 ? 0.45742 0.62572 0.47653 0.10462  0.08581  -0.02024 97  LYS A C   
1468 O  O   . LYS A 117 ? 0.43866 0.59252 0.45534 0.11160  0.07964  -0.02517 97  LYS A O   
1469 C  CB  . LYS A 117 ? 0.41775 0.60930 0.43131 0.11463  0.10576  -0.02173 97  LYS A CB  
1472 N  N   . ARG A 118 ? 0.39961 0.58270 0.43514 0.09410  0.08387  -0.01210 98  ARG A N   
1473 C  CA  . ARG A 118 ? 0.37204 0.55549 0.42230 0.09158  0.07428  -0.00958 98  ARG A CA  
1474 C  C   . ARG A 118 ? 0.36981 0.52559 0.40571 0.08734  0.06427  -0.01221 98  ARG A C   
1475 O  O   . ARG A 118 ? 0.37469 0.52251 0.41414 0.09096  0.05694  -0.01337 98  ARG A O   
1476 C  CB  . ARG A 118 ? 0.42184 0.62428 0.49062 0.08023  0.07316  -0.00102 98  ARG A CB  
1477 C  CG  . ARG A 118 ? 0.54909 0.78051 0.64304 0.08525  0.07743  0.00248  98  ARG A CG  
1478 C  CD  . ARG A 118 ? 0.49594 0.74160 0.60911 0.07315  0.07230  0.01030  98  ARG A CD  
1479 N  NE  . ARG A 118 ? 0.54670 0.78701 0.66810 0.07343  0.06020  0.00982  98  ARG A NE  
1480 C  CZ  . ARG A 118 ? 0.60516 0.85995 0.74448 0.08173  0.05773  0.00968  98  ARG A CZ  
1481 N  NH1 . ARG A 118 ? 0.58587 0.86280 0.73883 0.09091  0.06712  0.00975  98  ARG A NH1 
1482 N  NH2 . ARG A 118 ? 0.59365 0.84098 0.73704 0.08133  0.04563  0.00959  98  ARG A NH2 
1496 N  N   . VAL A 119 ? 0.37615 0.51778 0.39630 0.07972  0.06395  -0.01256 99  VAL A N   
1497 C  CA  . VAL A 119 ? 0.31743 0.43519 0.32581 0.07544  0.05562  -0.01447 99  VAL A CA  
1498 C  C   . VAL A 119 ? 0.36718 0.46659 0.36314 0.08498  0.05426  -0.02166 99  VAL A C   
1499 O  O   . VAL A 119 ? 0.33751 0.42345 0.33266 0.08666  0.04744  -0.02259 99  VAL A O   
1500 C  CB  . VAL A 119 ? 0.31231 0.42190 0.30981 0.06488  0.05534  -0.01257 99  VAL A CB  
1501 C  CG1 . VAL A 119 ? 0.34798 0.43415 0.33415 0.06177  0.04800  -0.01499 99  VAL A CG1 
1502 C  CG2 . VAL A 119 ? 0.37107 0.49485 0.38104 0.05475  0.05466  -0.00527 99  VAL A CG2 
1512 N  N   . LYS A 120 ? 0.39342 0.49121 0.37877 0.09159  0.06056  -0.02675 100 LYS A N   
1513 C  CA  . LYS A 120 ? 0.38667 0.46483 0.35949 0.10056  0.05840  -0.03438 100 LYS A CA  
1514 C  C   . LYS A 120 ? 0.38222 0.46192 0.36514 0.11093  0.05618  -0.03588 100 LYS A C   
1515 O  O   . LYS A 120 ? 0.43827 0.49768 0.41431 0.11491  0.05031  -0.03948 100 LYS A O   
1516 C  CB  . LYS A 120 ? 0.44715 0.52465 0.40614 0.10708  0.06556  -0.04031 100 LYS A CB  
1517 C  CG  . LYS A 120 ? 0.73896 0.78991 0.67854 0.10870  0.06090  -0.04762 100 LYS A CG  
1518 C  CD  . LYS A 120 ? 0.81158 0.85008 0.74814 0.12160  0.05903  -0.05479 100 LYS A CD  
1519 C  CE  . LYS A 120 ? 0.76392 0.77849 0.67967 0.12467  0.05608  -0.06352 100 LYS A CE  
1520 N  NZ  . LYS A 120 ? 0.86260 0.85568 0.77404 0.11502  0.04643  -0.06254 100 LYS A NZ  
1534 N  N   . ASP A 121 ? 0.36408 0.46756 0.36456 0.11481  0.06007  -0.03242 101 ASP A N   
1535 C  CA  . ASP A 121 ? 0.37714 0.48452 0.38943 0.12517  0.05730  -0.03322 101 ASP A CA  
1536 C  C   . ASP A 121 ? 0.38177 0.47887 0.39843 0.12059  0.04694  -0.02926 101 ASP A C   
1537 O  O   . ASP A 121 ? 0.42253 0.51650 0.44491 0.12961  0.04280  -0.03019 101 ASP A O   
1538 C  CB  . ASP A 121 ? 0.38898 0.52752 0.42189 0.12957  0.06380  -0.02977 101 ASP A CB  
1539 C  CG  . ASP A 121 ? 0.55802 0.70772 0.58738 0.13957  0.07530  -0.03450 101 ASP A CG  
1540 O  OD1 . ASP A 121 ? 0.55254 0.68389 0.56262 0.14560  0.07702  -0.04191 101 ASP A OD1 
1541 O  OD2 . ASP A 121 ? 0.51346 0.69081 0.55935 0.14099  0.08268  -0.03057 101 ASP A OD2 
1546 N  N   . LYS A 122 ? 0.38581 0.47702 0.39888 0.10772  0.04277  -0.02496 102 LYS A N   
1547 C  CA  . LYS A 122 ? 0.36712 0.44740 0.38085 0.10340  0.03379  -0.02133 102 LYS A CA  
1548 C  C   . LYS A 122 ? 0.38080 0.43325 0.37917 0.10496  0.02934  -0.02439 102 LYS A C   
1549 O  O   . LYS A 122 ? 0.35379 0.39522 0.35064 0.10265  0.02261  -0.02112 102 LYS A O   
1550 C  CB  . LYS A 122 ? 0.36347 0.44840 0.37875 0.08989  0.03182  -0.01611 102 LYS A CB  
1551 C  CG  . LYS A 122 ? 0.47549 0.58393 0.50934 0.08687  0.03071  -0.01102 102 LYS A CG  
1552 C  CD  . LYS A 122 ? 0.68431 0.78759 0.71832 0.07789  0.02249  -0.00665 102 LYS A CD  
1553 C  CE  . LYS A 122 ? 0.78966 0.89041 0.82857 0.08372  0.01427  -0.00513 102 LYS A CE  
1554 N  NZ  . LYS A 122 ? 0.48921 0.57958 0.52213 0.07676  0.00574  -0.00175 102 LYS A NZ  
1568 N  N   . GLU A 123 ? 0.37199 0.41259 0.35861 0.10854  0.03272  -0.03033 103 GLU A N   
1569 C  CA  . GLU A 123 ? 0.36822 0.38198 0.34123 0.10753  0.02809  -0.03288 103 GLU A CA  
1570 C  C   . GLU A 123 ? 0.36583 0.36665 0.34024 0.11386  0.02175  -0.03149 103 GLU A C   
1571 O  O   . GLU A 123 ? 0.37530 0.36072 0.34446 0.10796  0.01657  -0.02789 103 GLU A O   
1572 C  CB  . GLU A 123 ? 0.42714 0.43067 0.38832 0.11274  0.03156  -0.04075 103 GLU A CB  
1573 C  CG  . GLU A 123 ? 0.42646 0.40213 0.37545 0.11091  0.02588  -0.04353 103 GLU A CG  
1574 C  CD  . GLU A 123 ? 0.65089 0.61578 0.58644 0.11196  0.02766  -0.05112 103 GLU A CD  
1575 O  OE1 . GLU A 123 ? 0.71925 0.69837 0.65278 0.11319  0.03393  -0.05352 103 GLU A OE1 
1576 O  OE2 . GLU A 123 ? 0.73781 0.67961 0.66450 0.11069  0.02233  -0.05415 103 GLU A OE2 
1583 N  N   . ALA A 124 ? 0.38126 0.38830 0.36277 0.12616  0.02228  -0.03376 104 ALA A N   
1584 C  CA  . ALA A 124 ? 0.39409 0.38705 0.37596 0.13319  0.01564  -0.03225 104 ALA A CA  
1585 C  C   . ALA A 124 ? 0.38412 0.38015 0.37093 0.12687  0.00990  -0.02415 104 ALA A C   
1586 O  O   . ALA A 124 ? 0.39496 0.37198 0.37468 0.12558  0.00414  -0.02081 104 ALA A O   
1587 C  CB  . ALA A 124 ? 0.39767 0.40066 0.38895 0.14836  0.01722  -0.03581 104 ALA A CB  
1593 N  N   . SER A 125 ? 0.34464 0.36372 0.34278 0.12266  0.01124  -0.02075 105 SER A N   
1594 C  CA  . SER A 125 ? 0.34707 0.36877 0.34859 0.11770  0.00492  -0.01414 105 SER A CA  
1595 C  C   . SER A 125 ? 0.33300 0.34089 0.32259 0.10576  0.00357  -0.01108 105 SER A C   
1596 O  O   . SER A 125 ? 0.34159 0.33865 0.32573 0.10385  -0.00196 -0.00642 105 SER A O   
1597 C  CB  . SER A 125 ? 0.42085 0.47013 0.43865 0.11613  0.00562  -0.01188 105 SER A CB  
1598 O  OG  . SER A 125 ? 0.43390 0.49437 0.45302 0.10741  0.01147  -0.01249 105 SER A OG  
1604 N  N   . ILE A 126 ? 0.33681 0.34544 0.32203 0.09814  0.00868  -0.01334 106 ILE A N   
1605 C  CA  . ILE A 126 ? 0.33688 0.33325 0.31222 0.08757  0.00795  -0.01084 106 ILE A CA  
1606 C  C   . ILE A 126 ? 0.32927 0.30135 0.29412 0.08879  0.00533  -0.01046 106 ILE A C   
1607 O  O   . ILE A 126 ? 0.32198 0.28361 0.28080 0.08350  0.00263  -0.00564 106 ILE A O   
1608 C  CB  . ILE A 126 ? 0.29313 0.29499 0.26668 0.08059  0.01332  -0.01361 106 ILE A CB  
1609 C  CG1 . ILE A 126 ? 0.31276 0.33731 0.29685 0.07781  0.01563  -0.01231 106 ILE A CG1 
1610 C  CG2 . ILE A 126 ? 0.32268 0.31204 0.28771 0.07098  0.01237  -0.01126 106 ILE A CG2 
1611 C  CD1 . ILE A 126 ? 0.34399 0.37483 0.32640 0.07254  0.02107  -0.01443 106 ILE A CD1 
1623 N  N   . ALA A 127 ? 0.34640 0.30867 0.30855 0.09556  0.00631  -0.01549 107 ALA A N   
1624 C  CA  . ALA A 127 ? 0.38482 0.32253 0.33824 0.09642  0.00310  -0.01518 107 ALA A CA  
1625 C  C   . ALA A 127 ? 0.36754 0.29699 0.32027 0.10041  -0.00231 -0.00913 107 ALA A C   
1626 O  O   . ALA A 127 ? 0.37989 0.29233 0.32529 0.09583  -0.00472 -0.00439 107 ALA A O   
1627 C  CB  . ALA A 127 ? 0.41971 0.34854 0.37060 0.10486  0.00405  -0.02277 107 ALA A CB  
1633 N  N   . ALA A 128 ? 0.38353 0.32484 0.34405 0.10925  -0.00433 -0.00884 108 ALA A N   
1634 C  CA  . ALA A 128 ? 0.39801 0.33205 0.35713 0.11369  -0.01051 -0.00286 108 ALA A CA  
1635 C  C   . ALA A 128 ? 0.38479 0.31916 0.33853 0.10444  -0.01217 0.00405  108 ALA A C   
1636 O  O   . ALA A 128 ? 0.39509 0.31372 0.34024 0.10406  -0.01586 0.00999  108 ALA A O   
1637 C  CB  . ALA A 128 ? 0.40428 0.35490 0.37527 0.12457  -0.01294 -0.00395 108 ALA A CB  
1643 N  N   . LEU A 129 ? 0.35254 0.30406 0.31044 0.09748  -0.00948 0.00354  109 LEU A N   
1644 C  CA  . LEU A 129 ? 0.32250 0.27381 0.27406 0.08936  -0.01070 0.00879  109 LEU A CA  
1645 C  C   . LEU A 129 ? 0.36713 0.30148 0.30835 0.08180  -0.00783 0.01119  109 LEU A C   
1646 O  O   . LEU A 129 ? 0.36670 0.29190 0.29903 0.07877  -0.00934 0.01723  109 LEU A O   
1647 C  CB  . LEU A 129 ? 0.33298 0.30446 0.29168 0.08380  -0.00888 0.00701  109 LEU A CB  
1648 C  CG  . LEU A 129 ? 0.34270 0.33218 0.31232 0.08868  -0.01338 0.00723  109 LEU A CG  
1649 C  CD1 . LEU A 129 ? 0.35410 0.36238 0.33278 0.08235  -0.01038 0.00485  109 LEU A CD1 
1650 C  CD2 . LEU A 129 ? 0.40786 0.39261 0.37075 0.08959  -0.02058 0.01257  109 LEU A CD2 
1662 N  N   . CYS A 130 ? 0.33920 0.26955 0.28143 0.07891  -0.00378 0.00677  110 CYS A N   
1663 C  CA  . CYS A 130 ? 0.34938 0.26471 0.28485 0.07148  -0.00166 0.00906  110 CYS A CA  
1664 C  C   . CYS A 130 ? 0.39781 0.29296 0.32671 0.07446  -0.00484 0.01421  110 CYS A C   
1665 O  O   . CYS A 130 ? 0.39560 0.28107 0.31793 0.06877  -0.00402 0.02064  110 CYS A O   
1666 C  CB  . CYS A 130 ? 0.34754 0.26094 0.28551 0.06916  0.00126  0.00260  110 CYS A CB  
1667 S  SG  . CYS A 130 ? 0.35715 0.28977 0.30022 0.06360  0.00558  -0.00204 110 CYS A SG  
1673 N  N   . ASP A 131 ? 0.39123 0.27961 0.32182 0.08369  -0.00818 0.01188  111 ASP A N   
1674 C  CA  . ASP A 131 ? 0.41681 0.28367 0.34101 0.08663  -0.01183 0.01712  111 ASP A CA  
1675 C  C   . ASP A 131 ? 0.39452 0.26051 0.31254 0.08838  -0.01502 0.02543  111 ASP A C   
1676 O  O   . ASP A 131 ? 0.44093 0.28988 0.35072 0.08598  -0.01597 0.03277  111 ASP A O   
1677 C  CB  . ASP A 131 ? 0.47560 0.33418 0.40284 0.09725  -0.01503 0.01173  111 ASP A CB  
1678 C  CG  . ASP A 131 ? 0.58787 0.43646 0.51550 0.09476  -0.01318 0.00476  111 ASP A CG  
1679 O  OD1 . ASP A 131 ? 0.51737 0.35271 0.44143 0.08576  -0.01245 0.00735  111 ASP A OD1 
1680 O  OD2 . ASP A 131 ? 0.57325 0.42917 0.50509 0.10157  -0.01225 -0.00351 111 ASP A OD2 
1685 N  N   . THR A 132 ? 0.39857 0.28217 0.32005 0.09233  -0.01707 0.02478  112 THR A N   
1686 C  CA  . THR A 132 ? 0.43229 0.31524 0.34592 0.09378  -0.02115 0.03206  112 THR A CA  
1687 C  C   . THR A 132 ? 0.40027 0.28041 0.30427 0.08395  -0.01709 0.03729  112 THR A C   
1688 O  O   . THR A 132 ? 0.44693 0.31475 0.33924 0.08355  -0.01835 0.04530  112 THR A O   
1689 C  CB  . THR A 132 ? 0.45185 0.35568 0.37312 0.09867  -0.02497 0.02922  112 THR A CB  
1690 O  OG1 . THR A 132 ? 0.45438 0.36118 0.38517 0.10939  -0.02862 0.02563  112 THR A OG1 
1691 C  CG2 . THR A 132 ? 0.50131 0.40435 0.41259 0.09950  -0.03028 0.03589  112 THR A CG2 
1699 N  N   . LEU A 133 ? 0.38350 0.27505 0.29192 0.07664  -0.01198 0.03310  113 LEU A N   
1700 C  CA  . LEU A 133 ? 0.36306 0.25404 0.26394 0.06820  -0.00745 0.03708  113 LEU A CA  
1701 C  C   . LEU A 133 ? 0.38527 0.25874 0.28128 0.06329  -0.00379 0.04261  113 LEU A C   
1702 O  O   . LEU A 133 ? 0.41247 0.27958 0.29842 0.06006  -0.00145 0.04997  113 LEU A O   
1703 C  CB  . LEU A 133 ? 0.36310 0.26945 0.27112 0.06231  -0.00348 0.03114  113 LEU A CB  
1704 C  CG  . LEU A 133 ? 0.36390 0.28734 0.27553 0.06470  -0.00690 0.02780  113 LEU A CG  
1705 C  CD1 . LEU A 133 ? 0.34661 0.28326 0.26714 0.05933  -0.00315 0.02182  113 LEU A CD1 
1706 C  CD2 . LEU A 133 ? 0.41009 0.33263 0.30973 0.06433  -0.00919 0.03260  113 LEU A CD2 
1718 N  N   . ILE A 134 ? 0.40378 0.26930 0.30665 0.06250  -0.00325 0.03926  114 ILE A N   
1719 C  CA  . ILE A 134 ? 0.41771 0.26610 0.31824 0.05690  -0.00091 0.04468  114 ILE A CA  
1720 C  C   . ILE A 134 ? 0.45044 0.28148 0.34182 0.06147  -0.00453 0.05319  114 ILE A C   
1721 O  O   . ILE A 134 ? 0.44755 0.26692 0.33290 0.05608  -0.00162 0.06186  114 ILE A O   
1722 C  CB  . ILE A 134 ? 0.41575 0.25849 0.32513 0.05522  -0.00126 0.03795  114 ILE A CB  
1723 C  CG1 . ILE A 134 ? 0.41043 0.26860 0.32657 0.04928  0.00269  0.03177  114 ILE A CG1 
1724 C  CG2 . ILE A 134 ? 0.40248 0.22475 0.31096 0.04971  -0.00104 0.04378  114 ILE A CG2 
1725 C  CD1 . ILE A 134 ? 0.43316 0.28826 0.35599 0.04882  0.00155  0.02371  114 ILE A CD1 
1737 N  N   . ASP A 135 ? 0.44067 0.26975 0.33157 0.07160  -0.01084 0.05139  115 ASP A N   
1738 C  CA  . ASP A 135 ? 0.49675 0.30980 0.37795 0.07700  -0.01534 0.05987  115 ASP A CA  
1739 C  C   . ASP A 135 ? 0.46904 0.28348 0.33693 0.07450  -0.01350 0.06885  115 ASP A C   
1740 O  O   . ASP A 135 ? 0.51036 0.30868 0.36753 0.07491  -0.01440 0.07865  115 ASP A O   
1741 C  CB  . ASP A 135 ? 0.49751 0.31364 0.38168 0.08932  -0.02277 0.05597  115 ASP A CB  
1742 C  CG  . ASP A 135 ? 0.55690 0.36326 0.44925 0.09501  -0.02549 0.04973  115 ASP A CG  
1743 O  OD1 . ASP A 135 ? 0.51362 0.30723 0.40798 0.08956  -0.02319 0.04853  115 ASP A OD1 
1744 O  OD2 . ASP A 135 ? 0.57166 0.38289 0.46852 0.10593  -0.03065 0.04586  115 ASP A OD2 
1749 N  N   . ALA A 136 ? 0.45199 0.28430 0.31907 0.07231  -0.01113 0.06576  116 ALA A N   
1750 C  CA  . ALA A 136 ? 0.47464 0.30803 0.32694 0.07130  -0.00984 0.07275  116 ALA A CA  
1751 C  C   . ALA A 136 ? 0.54521 0.37170 0.39129 0.06238  -0.00125 0.08011  116 ALA A C   
1752 O  O   . ALA A 136 ? 0.58336 0.40576 0.41406 0.06245  0.00063  0.08805  116 ALA A O   
1753 C  CB  . ALA A 136 ? 0.47723 0.33046 0.33039 0.07186  -0.01078 0.06635  116 ALA A CB  
1759 N  N   . VAL A 137 ? 0.50164 0.32731 0.35902 0.05497  0.00394  0.07791  117 VAL A N   
1760 C  CA  . VAL A 137 ? 0.49858 0.32074 0.35378 0.04607  0.01244  0.08506  117 VAL A CA  
1761 C  C   . VAL A 137 ? 0.51165 0.31724 0.37356 0.04080  0.01350  0.09012  117 VAL A C   
1762 O  O   . VAL A 137 ? 0.49006 0.29156 0.35097 0.03322  0.02042  0.09838  117 VAL A O   
1763 C  CB  . VAL A 137 ? 0.50351 0.34283 0.36708 0.04005  0.01834  0.07870  117 VAL A CB  
1764 C  CG1 . VAL A 137 ? 0.55051 0.40365 0.40601 0.04436  0.01718  0.07468  117 VAL A CG1 
1765 C  CG2 . VAL A 137 ? 0.47491 0.31833 0.35487 0.03794  0.01631  0.06935  117 VAL A CG2 
1775 N  N   . CYS A 138 ? 0.49033 0.28644 0.35963 0.04445  0.00702  0.08533  118 CYS A N   
1776 C  CA  . CYS A 138 ? 0.50724 0.28805 0.38511 0.03834  0.00707  0.08741  118 CYS A CA  
1777 C  C   . CYS A 138 ? 0.54326 0.30485 0.41249 0.03547  0.00839  0.10141  118 CYS A C   
1778 O  O   . CYS A 138 ? 0.53873 0.29052 0.41523 0.02663  0.01117  0.10632  118 CYS A O   
1779 C  CB  . CYS A 138 ? 0.50837 0.28206 0.39350 0.04466  -0.00059 0.07797  118 CYS A CB  
1780 S  SG  . CYS A 138 ? 0.57257 0.33507 0.44892 0.05855  -0.00936 0.07901  118 CYS A SG  
1786 N  N   . GLU A 139 ? 0.57707 0.33316 0.43103 0.04218  0.00630  0.10861  119 GLU A N   
1787 C  CA  . GLU A 139 ? 0.59995 0.33731 0.44368 0.03946  0.00802  0.12326  119 GLU A CA  
1788 C  C   . GLU A 139 ? 0.56015 0.30476 0.39850 0.03098  0.01901  0.13284  119 GLU A C   
1789 O  O   . GLU A 139 ? 0.57199 0.30228 0.40507 0.02590  0.02271  0.14600  119 GLU A O   
1790 C  CB  . GLU A 139 ? 0.61125 0.33958 0.43872 0.05040  0.00122  0.12810  119 GLU A CB  
1791 C  CG  . GLU A 139 ? 0.69790 0.41313 0.53063 0.05897  -0.00914 0.12251  119 GLU A CG  
1792 C  CD  . GLU A 139 ? 0.75968 0.47199 0.57961 0.07127  -0.01697 0.12472  119 GLU A CD  
1793 O  OE1 . GLU A 139 ? 0.77838 0.50906 0.59393 0.07584  -0.01770 0.12000  119 GLU A OE1 
1794 O  OE2 . GLU A 139 ? 0.80547 0.50011 0.62272 0.07525  -0.02291 0.13040  119 GLU A OE2 
1801 N  N   . ARG A 140 ? 0.56106 0.32702 0.40084 0.02962  0.02448  0.12685  120 ARG A N   
1802 C  CA  . ARG A 140 ? 0.54319 0.31784 0.37500 0.02461  0.03514  0.13491  120 ARG A CA  
1803 C  C   . ARG A 140 ? 0.56253 0.34147 0.41050 0.01275  0.04353  0.13797  120 ARG A C   
1804 O  O   . ARG A 140 ? 0.58387 0.36389 0.42709 0.00740  0.05310  0.14905  120 ARG A O   
1805 C  CB  . ARG A 140 ? 0.59304 0.38760 0.41861 0.02928  0.03665  0.12659  120 ARG A CB  
1806 C  CG  . ARG A 140 ? 0.70547 0.49906 0.51351 0.03990  0.02950  0.12522  120 ARG A CG  
1807 C  CD  . ARG A 140 ? 0.69693 0.50969 0.50762 0.04341  0.02736  0.11263  120 ARG A CD  
1808 N  NE  . ARG A 140 ? 0.90838 0.72195 0.70416 0.05272  0.01964  0.11087  120 ARG A NE  
1809 C  CZ  . ARG A 140 ? 1.07688 0.90353 0.86563 0.05565  0.01888  0.10477  120 ARG A CZ  
1810 N  NH1 . ARG A 140 ? 0.88370 0.72390 0.67921 0.05089  0.02535  0.09903  120 ARG A NH1 
1811 N  NH2 . ARG A 140 ? 1.18605 1.01148 0.96104 0.06367  0.01053  0.10427  120 ARG A NH2 
1825 N  N   . GLY A 141 ? 0.51195 0.29476 0.37885 0.00875  0.04036  0.12843  121 GLY A N   
1826 C  CA  . GLY A 141 ? 0.50466 0.29378 0.38872 -0.00237 0.04686  0.13023  121 GLY A CA  
1827 C  C   . GLY A 141 ? 0.48039 0.29256 0.36895 -0.00426 0.05446  0.12549  121 GLY A C   
1828 O  O   . GLY A 141 ? 0.46382 0.28373 0.36856 -0.01299 0.05957  0.12649  121 GLY A O   
1832 N  N   . GLU A 142 ? 0.44480 0.26751 0.32029 0.00365  0.05463  0.12038  122 GLU A N   
1833 C  CA  . GLU A 142 ? 0.42259 0.26522 0.30044 0.00341  0.06062  0.11475  122 GLU A CA  
1834 C  C   . GLU A 142 ? 0.44193 0.29104 0.30998 0.01247  0.05432  0.10463  122 GLU A C   
1835 O  O   . GLU A 142 ? 0.47537 0.31601 0.32865 0.01944  0.04911  0.10638  122 GLU A O   
1836 C  CB  . GLU A 142 ? 0.45185 0.29987 0.31944 0.00187  0.07238  0.12518  122 GLU A CB  
1837 C  CG  . GLU A 142 ? 0.46171 0.32980 0.33714 -0.00005 0.08015  0.12028  122 GLU A CG  
1838 C  CD  . GLU A 142 ? 0.43572 0.31337 0.29814 0.00833  0.07809  0.11093  122 GLU A CD  
1839 O  OE1 . GLU A 142 ? 0.52686 0.39727 0.37317 0.01551  0.07134  0.10913  122 GLU A OE1 
1840 O  OE2 . GLU A 142 ? 0.45524 0.34764 0.32435 0.00768  0.08276  0.10538  122 GLU A OE2 
1847 N  N   . CYS A 143 ? 0.40171 0.26582 0.27843 0.01214  0.05448  0.09476  123 CYS A N   
1848 C  CA  . CYS A 143 ? 0.43293 0.30553 0.30050 0.01931  0.05038  0.08655  123 CYS A CA  
1849 C  C   . CYS A 143 ? 0.41461 0.30334 0.28958 0.01700  0.05505  0.08023  123 CYS A C   
1850 O  O   . CYS A 143 ? 0.40113 0.29538 0.28975 0.01052  0.06048  0.08131  123 CYS A O   
1851 C  CB  . CYS A 143 ? 0.40881 0.27876 0.28043 0.02388  0.04000  0.07839  123 CYS A CB  
1852 S  SG  . CYS A 143 ? 0.42604 0.30292 0.31852 0.01963  0.03698  0.06808  123 CYS A SG  
1858 N  N   . ASP A 144 ? 0.41158 0.30764 0.27814 0.02240  0.05213  0.07356  124 ASP A N   
1859 C  CA  . ASP A 144 ? 0.35152 0.26091 0.22542 0.02123  0.05390  0.06591  124 ASP A CA  
1860 C  C   . ASP A 144 ? 0.35867 0.27107 0.24400 0.02125  0.04593  0.05718  124 ASP A C   
1861 O  O   . ASP A 144 ? 0.37742 0.28886 0.25718 0.02620  0.03896  0.05335  124 ASP A O   
1862 C  CB  . ASP A 144 ? 0.36380 0.27753 0.22178 0.02666  0.05471  0.06356  124 ASP A CB  
1863 C  CG  . ASP A 144 ? 0.39514 0.32067 0.26036 0.02567  0.05657  0.05609  124 ASP A CG  
1864 O  OD1 . ASP A 144 ? 0.37287 0.30409 0.25435 0.02198  0.05431  0.05090  124 ASP A OD1 
1865 O  OD2 . ASP A 144 ? 0.51251 0.44086 0.36598 0.02890  0.06084  0.05574  124 ASP A OD2 
1870 N  N   . PHE A 145 ? 0.35004 0.26595 0.25145 0.01582  0.04678  0.05460  125 PHE A N   
1871 C  CA  . PHE A 145 ? 0.34163 0.25927 0.25214 0.01605  0.04002  0.04696  125 PHE A CA  
1872 C  C   . PHE A 145 ? 0.33108 0.25811 0.23890 0.01964  0.03644  0.03975  125 PHE A C   
1873 O  O   . PHE A 145 ? 0.32796 0.25571 0.23718 0.02263  0.03050  0.03523  125 PHE A O   
1874 C  CB  . PHE A 145 ? 0.30450 0.22500 0.23048 0.00966  0.04135  0.04498  125 PHE A CB  
1875 C  CG  . PHE A 145 ? 0.32681 0.24560 0.25991 0.00988  0.03497  0.03834  125 PHE A CG  
1876 C  CD1 . PHE A 145 ? 0.32043 0.22723 0.25576 0.00939  0.03175  0.03966  125 PHE A CD1 
1877 C  CD2 . PHE A 145 ? 0.31700 0.24532 0.25347 0.01085  0.03246  0.03100  125 PHE A CD2 
1878 C  CE1 . PHE A 145 ? 0.34770 0.25246 0.28740 0.01085  0.02639  0.03282  125 PHE A CE1 
1879 C  CE2 . PHE A 145 ? 0.29846 0.22573 0.23956 0.01174  0.02760  0.02509  125 PHE A CE2 
1880 C  CZ  . PHE A 145 ? 0.31753 0.23326 0.25978 0.01206  0.02485  0.02569  125 PHE A CZ  
1890 N  N   . VAL A 146 ? 0.33939 0.27349 0.24367 0.01960  0.03997  0.03874  126 VAL A N   
1891 C  CA  . VAL A 146 ? 0.33978 0.28098 0.24152 0.02226  0.03586  0.03231  126 VAL A CA  
1892 C  C   . VAL A 146 ? 0.35120 0.28894 0.24117 0.02774  0.03043  0.03255  126 VAL A C   
1893 O  O   . VAL A 146 ? 0.35896 0.30008 0.25252 0.02960  0.02424  0.02836  126 VAL A O   
1894 C  CB  . VAL A 146 ? 0.32714 0.27411 0.22652 0.02171  0.04044  0.03098  126 VAL A CB  
1895 C  CG1 . VAL A 146 ? 0.39170 0.34280 0.28603 0.02451  0.03511  0.02494  126 VAL A CG1 
1896 C  CG2 . VAL A 146 ? 0.34089 0.29354 0.25478 0.01668  0.04425  0.02992  126 VAL A CG2 
1906 N  N   . ARG A 147 ? 0.35791 0.28949 0.23380 0.03053  0.03267  0.03788  127 ARG A N   
1907 C  CA  . ARG A 147 ? 0.35791 0.28603 0.22077 0.03609  0.02649  0.03817  127 ARG A CA  
1908 C  C   . ARG A 147 ? 0.37574 0.29934 0.24199 0.03869  0.02063  0.03955  127 ARG A C   
1909 O  O   . ARG A 147 ? 0.40707 0.33321 0.27158 0.04272  0.01310  0.03674  127 ARG A O   
1910 C  CB  . ARG A 147 ? 0.39590 0.31716 0.24058 0.03872  0.03093  0.04433  127 ARG A CB  
1911 C  CG  . ARG A 147 ? 0.47185 0.38908 0.29963 0.04485  0.02369  0.04416  127 ARG A CG  
1912 C  CD  . ARG A 147 ? 0.48619 0.39423 0.29364 0.04795  0.02829  0.05191  127 ARG A CD  
1913 N  NE  . ARG A 147 ? 0.52202 0.42260 0.33275 0.04605  0.03226  0.06027  127 ARG A NE  
1914 C  CZ  . ARG A 147 ? 0.54542 0.44090 0.34937 0.04428  0.04145  0.06856  127 ARG A CZ  
1915 N  NH1 . ARG A 147 ? 0.62697 0.52426 0.41768 0.04563  0.04853  0.06995  127 ARG A NH1 
1916 N  NH2 . ARG A 147 ? 0.53326 0.42157 0.34406 0.04116  0.04377  0.07565  127 ARG A NH2 
1930 N  N   . ASP A 148 ? 0.37055 0.28731 0.24239 0.03668  0.02346  0.04377  128 ASP A N   
1931 C  CA  . ASP A 148 ? 0.36581 0.27460 0.23752 0.04051  0.01840  0.04624  128 ASP A CA  
1932 C  C   . ASP A 148 ? 0.36952 0.28149 0.25595 0.04038  0.01520  0.04068  128 ASP A C   
1933 O  O   . ASP A 148 ? 0.37458 0.28257 0.26180 0.04545  0.00993  0.04064  128 ASP A O   
1934 C  CB  . ASP A 148 ? 0.39829 0.29397 0.26415 0.03913  0.02264  0.05523  128 ASP A CB  
1935 C  CG  . ASP A 148 ? 0.49579 0.38783 0.34415 0.04048  0.02650  0.06178  128 ASP A CG  
1936 O  OD1 . ASP A 148 ? 0.49449 0.38947 0.33153 0.04529  0.02204  0.05966  128 ASP A OD1 
1937 O  OD2 . ASP A 148 ? 0.45465 0.34065 0.30030 0.03684  0.03369  0.06921  128 ASP A OD2 
1942 N  N   . LEU A 149 ? 0.33505 0.25366 0.23224 0.03544  0.01826  0.03612  129 LEU A N   
1943 C  CA  . LEU A 149 ? 0.33611 0.25700 0.24467 0.03562  0.01589  0.03073  129 LEU A CA  
1944 C  C   . LEU A 149 ? 0.33103 0.26530 0.24691 0.03355  0.01580  0.02416  129 LEU A C   
1945 O  O   . LEU A 149 ? 0.32606 0.26718 0.24683 0.03671  0.01224  0.01992  129 LEU A O   
1946 C  CB  . LEU A 149 ? 0.34628 0.25805 0.26037 0.03125  0.01874  0.03236  129 LEU A CB  
1947 C  CG  . LEU A 149 ? 0.37633 0.27285 0.28495 0.03290  0.01802  0.03907  129 LEU A CG  
1948 C  CD1 . LEU A 149 ? 0.38945 0.27651 0.30426 0.02689  0.02053  0.04153  129 LEU A CD1 
1949 C  CD2 . LEU A 149 ? 0.42401 0.31459 0.33164 0.04057  0.01183  0.03745  129 LEU A CD2 
1961 N  N   . ALA A 150 ? 0.30530 0.24392 0.22238 0.02858  0.01979  0.02372  130 ALA A N   
1962 C  CA  . ALA A 150 ? 0.31435 0.26349 0.23880 0.02605  0.01957  0.01814  130 ALA A CA  
1963 C  C   . ALA A 150 ? 0.29093 0.24862 0.21348 0.02820  0.01601  0.01564  130 ALA A C   
1964 O  O   . ALA A 150 ? 0.29534 0.26115 0.22492 0.02821  0.01385  0.01170  130 ALA A O   
1965 C  CB  . ALA A 150 ? 0.29833 0.24929 0.22566 0.02073  0.02413  0.01845  130 ALA A CB  
1971 N  N   . ALA A 151 ? 0.30780 0.26374 0.22092 0.02988  0.01513  0.01789  131 ALA A N   
1972 C  CA  . ALA A 151 ? 0.32775 0.29055 0.23947 0.03137  0.01012  0.01514  131 ALA A CA  
1973 C  C   . ALA A 151 ? 0.31149 0.27682 0.22531 0.03610  0.00425  0.01511  131 ALA A C   
1974 O  O   . ALA A 151 ? 0.31115 0.28639 0.23294 0.03593  0.00056  0.01193  131 ALA A O   
1975 C  CB  . ALA A 151 ? 0.35684 0.31587 0.25593 0.03214  0.01019  0.01642  131 ALA A CB  
1981 N  N   . PRO A 152 ? 0.33062 0.28803 0.23926 0.04032  0.00323  0.01888  132 PRO A N   
1982 C  CA  . PRO A 152 ? 0.32114 0.28198 0.23242 0.04588  -0.00325 0.01878  132 PRO A CA  
1983 C  C   . PRO A 152 ? 0.30969 0.27807 0.23458 0.04744  -0.00337 0.01555  132 PRO A C   
1984 O  O   . PRO A 152 ? 0.30769 0.28548 0.23960 0.05089  -0.00816 0.01409  132 PRO A O   
1985 C  CB  . PRO A 152 ? 0.34192 0.28983 0.24262 0.05025  -0.00405 0.02445  132 PRO A CB  
1986 C  CG  . PRO A 152 ? 0.44262 0.38214 0.33364 0.04655  0.00185  0.02790  132 PRO A CG  
1987 C  CD  . PRO A 152 ? 0.34248 0.28780 0.24061 0.04047  0.00704  0.02433  132 PRO A CD  
1995 N  N   . LEU A 153 ? 0.28859 0.25330 0.21738 0.04559  0.00148  0.01437  133 LEU A N   
1996 C  CA  . LEU A 153 ? 0.30488 0.27543 0.24359 0.04885  0.00142  0.01093  133 LEU A CA  
1997 C  C   . LEU A 153 ? 0.29347 0.28011 0.24164 0.04672  0.00117  0.00746  133 LEU A C   
1998 O  O   . LEU A 153 ? 0.27654 0.27317 0.23282 0.05117  -0.00149 0.00635  133 LEU A O   
1999 C  CB  . LEU A 153 ? 0.29035 0.25187 0.22929 0.04742  0.00553  0.00961  133 LEU A CB  
2000 C  CG  . LEU A 153 ? 0.31897 0.28337 0.26472 0.05168  0.00619  0.00507  133 LEU A CG  
2001 C  CD1 . LEU A 153 ? 0.31010 0.28759 0.26195 0.04801  0.00885  0.00132  133 LEU A CD1 
2002 C  CD2 . LEU A 153 ? 0.33507 0.30280 0.28453 0.06048  0.00243  0.00502  133 LEU A CD2 
2014 N  N   . PRO A 154 ? 0.27533 0.26569 0.22408 0.04025  0.00375  0.00615  134 PRO A N   
2015 C  CA  . PRO A 154 ? 0.26553 0.27032 0.22356 0.03785  0.00335  0.00395  134 PRO A CA  
2016 C  C   . PRO A 154 ? 0.26339 0.27635 0.22489 0.03887  -0.00262 0.00494  134 PRO A C   
2017 O  O   . PRO A 154 ? 0.28101 0.30743 0.25376 0.03944  -0.00389 0.00411  134 PRO A O   
2018 C  CB  . PRO A 154 ? 0.28000 0.28340 0.23574 0.03100  0.00622  0.00323  134 PRO A CB  
2019 C  CG  . PRO A 154 ? 0.28901 0.27948 0.23786 0.03049  0.00962  0.00399  134 PRO A CG  
2020 C  CD  . PRO A 154 ? 0.30993 0.29218 0.25239 0.03506  0.00726  0.00701  134 PRO A CD  
2028 N  N   . MET A 155 ? 0.26690 0.27223 0.21896 0.03936  -0.00638 0.00686  135 MET A N   
2029 C  CA  . MET A 155 ? 0.27531 0.28684 0.22922 0.04047  -0.01380 0.00728  135 MET A CA  
2030 C  C   . MET A 155 ? 0.30164 0.32028 0.26390 0.04704  -0.01757 0.00805  135 MET A C   
2031 O  O   . MET A 155 ? 0.29686 0.32903 0.27081 0.04701  -0.02218 0.00752  135 MET A O   
2032 C  CB  . MET A 155 ? 0.31225 0.31286 0.25118 0.04059  -0.01711 0.00872  135 MET A CB  
2033 C  CG  . MET A 155 ? 0.31441 0.31869 0.25245 0.04298  -0.02652 0.00894  135 MET A CG  
2034 S  SD  . MET A 155 ? 0.33708 0.35240 0.28507 0.03545  -0.03068 0.00552  135 MET A SD  
2035 C  CE  . MET A 155 ? 0.38360 0.41649 0.35080 0.03755  -0.03741 0.00596  135 MET A CE  
2045 N  N   . ALA A 156 ? 0.27953 0.28947 0.23737 0.05271  -0.01587 0.00945  136 ALA A N   
2046 C  CA  . ALA A 156 ? 0.28978 0.30522 0.25533 0.06042  -0.01969 0.01007  136 ALA A CA  
2047 C  C   . ALA A 156 ? 0.28219 0.31341 0.26410 0.06150  -0.01617 0.00732  136 ALA A C   
2048 O  O   . ALA A 156 ? 0.28054 0.32569 0.27517 0.06546  -0.02002 0.00738  136 ALA A O   
2049 C  CB  . ALA A 156 ? 0.30056 0.30033 0.25694 0.06618  -0.01857 0.01225  136 ALA A CB  
2055 N  N   . VAL A 157 ? 0.27017 0.30024 0.25198 0.05814  -0.00883 0.00512  137 VAL A N   
2056 C  CA  . VAL A 157 ? 0.26683 0.31122 0.26120 0.05960  -0.00433 0.00271  137 VAL A CA  
2057 C  C   . VAL A 157 ? 0.28559 0.34811 0.29265 0.05482  -0.00628 0.00348  137 VAL A C   
2058 O  O   . VAL A 157 ? 0.27066 0.34967 0.29240 0.05852  -0.00665 0.00362  137 VAL A O   
2059 C  CB  . VAL A 157 ? 0.24152 0.27962 0.23039 0.05643  0.00285  0.00025  137 VAL A CB  
2060 C  CG1 . VAL A 157 ? 0.28641 0.33974 0.28537 0.05712  0.00816  -0.00185 137 VAL A CG1 
2061 C  CG2 . VAL A 157 ? 0.28069 0.30145 0.26001 0.06136  0.00398  -0.00076 137 VAL A CG2 
2071 N  N   . ILE A 158 ? 0.26539 0.32530 0.26803 0.04652  -0.00743 0.00410  138 ILE A N   
2072 C  CA  . ILE A 158 ? 0.27387 0.34884 0.28865 0.04061  -0.00949 0.00500  138 ILE A CA  
2073 C  C   . ILE A 158 ? 0.30522 0.38739 0.32741 0.04243  -0.01876 0.00642  138 ILE A C   
2074 O  O   . ILE A 158 ? 0.29141 0.39123 0.33049 0.04076  -0.02098 0.00755  138 ILE A O   
2075 C  CB  . ILE A 158 ? 0.26337 0.33151 0.27102 0.03187  -0.00866 0.00485  138 ILE A CB  
2076 C  CG1 . ILE A 158 ? 0.30751 0.39064 0.32849 0.02556  -0.00709 0.00608  138 ILE A CG1 
2077 C  CG2 . ILE A 158 ? 0.27613 0.33334 0.27350 0.02981  -0.01555 0.00492  138 ILE A CG2 
2078 C  CD1 . ILE A 158 ? 0.32120 0.41208 0.34658 0.02681  0.00195  0.00594  138 ILE A CD1 
2090 N  N   . GLY A 159 ? 0.27264 0.34199 0.28286 0.04597  -0.02443 0.00681  139 GLY A N   
2091 C  CA  . GLY A 159 ? 0.29913 0.37402 0.31443 0.04892  -0.03440 0.00801  139 GLY A CA  
2092 C  C   . GLY A 159 ? 0.30125 0.39114 0.33299 0.05642  -0.03498 0.00873  139 GLY A C   
2093 O  O   . GLY A 159 ? 0.31775 0.42411 0.36588 0.05603  -0.04103 0.00971  139 GLY A O   
2097 N  N   . ASP A 160 ? 0.29334 0.37826 0.32221 0.06343  -0.02879 0.00807  140 ASP A N   
2098 C  CA  . ASP A 160 ? 0.29880 0.39770 0.34316 0.07211  -0.02848 0.00808  140 ASP A CA  
2099 C  C   . ASP A 160 ? 0.30025 0.42257 0.36500 0.06894  -0.02364 0.00795  140 ASP A C   
2100 O  O   . ASP A 160 ? 0.32086 0.46210 0.40460 0.07316  -0.02673 0.00912  140 ASP A O   
2101 C  CB  . ASP A 160 ? 0.32806 0.41445 0.36387 0.08021  -0.02273 0.00650  140 ASP A CB  
2102 C  CG  . ASP A 160 ? 0.34493 0.41199 0.36590 0.08558  -0.02877 0.00836  140 ASP A CG  
2103 O  OD1 . ASP A 160 ? 0.36172 0.42459 0.37654 0.08358  -0.03694 0.01076  140 ASP A OD1 
2104 O  OD2 . ASP A 160 ? 0.38897 0.44371 0.40328 0.09198  -0.02549 0.00754  140 ASP A OD2 
2109 N  N   . MET A 161 ? 0.29756 0.41961 0.35929 0.06165  -0.01608 0.00716  141 MET A N   
2110 C  CA  . MET A 161 ? 0.28079 0.42399 0.35984 0.05751  -0.01062 0.00828  141 MET A CA  
2111 C  C   . MET A 161 ? 0.29910 0.45674 0.39365 0.05045  -0.01863 0.01118  141 MET A C   
2112 O  O   . MET A 161 ? 0.28267 0.46304 0.39852 0.04930  -0.01667 0.01345  141 MET A O   
2113 C  CB  . MET A 161 ? 0.29480 0.43136 0.36413 0.05061  -0.00248 0.00751  141 MET A CB  
2114 C  CG  . MET A 161 ? 0.34563 0.47679 0.40723 0.05728  0.00648  0.00458  141 MET A CG  
2115 S  SD  . MET A 161 ? 0.38763 0.50371 0.43206 0.05003  0.01263  0.00314  141 MET A SD  
2116 C  CE  . MET A 161 ? 0.46150 0.59492 0.51828 0.03983  0.01525  0.00699  141 MET A CE  
2126 N  N   . LEU A 162 ? 0.29773 0.44260 0.38204 0.04545  -0.02757 0.01115  142 LEU A N   
2127 C  CA  . LEU A 162 ? 0.33449 0.48939 0.43117 0.03814  -0.03694 0.01295  142 LEU A CA  
2128 C  C   . LEU A 162 ? 0.34297 0.50252 0.44638 0.04358  -0.04878 0.01341  142 LEU A C   
2129 O  O   . LEU A 162 ? 0.38912 0.55517 0.50167 0.03766  -0.05878 0.01429  142 LEU A O   
2130 C  CB  . LEU A 162 ? 0.28877 0.42662 0.36955 0.02926  -0.04013 0.01182  142 LEU A CB  
2131 C  CG  . LEU A 162 ? 0.31928 0.45466 0.39694 0.02182  -0.03139 0.01216  142 LEU A CG  
2132 C  CD1 . LEU A 162 ? 0.34318 0.45747 0.40122 0.01671  -0.03472 0.01007  142 LEU A CD1 
2133 C  CD2 . LEU A 162 ? 0.36700 0.52267 0.46683 0.01392  -0.03080 0.01565  142 LEU A CD2 
2145 N  N   . GLY A 163 ? 0.29641 0.45210 0.39564 0.05466  -0.04893 0.01286  143 GLY A N   
2146 C  CA  . GLY A 163 ? 0.33120 0.49220 0.43757 0.06089  -0.06055 0.01384  143 GLY A CA  
2147 C  C   . GLY A 163 ? 0.34096 0.48164 0.42612 0.06080  -0.07121 0.01322  143 GLY A C   
2148 O  O   . GLY A 163 ? 0.38845 0.53393 0.47911 0.06316  -0.08365 0.01407  143 GLY A O   
2152 N  N   . VAL A 164 ? 0.35123 0.46997 0.41224 0.05832  -0.06670 0.01187  144 VAL A N   
2153 C  CA  . VAL A 164 ? 0.33520 0.43401 0.37325 0.05851  -0.07445 0.01148  144 VAL A CA  
2154 C  C   . VAL A 164 ? 0.39645 0.48453 0.42347 0.06928  -0.07625 0.01327  144 VAL A C   
2155 O  O   . VAL A 164 ? 0.39506 0.47741 0.41869 0.07401  -0.06722 0.01361  144 VAL A O   
2156 C  CB  . VAL A 164 ? 0.35477 0.43649 0.37354 0.05211  -0.06755 0.00983  144 VAL A CB  
2157 C  CG1 . VAL A 164 ? 0.37484 0.43656 0.36847 0.05332  -0.07429 0.00956  144 VAL A CG1 
2158 C  CG2 . VAL A 164 ? 0.35793 0.44843 0.38729 0.04159  -0.06543 0.00846  144 VAL A CG2 
2168 N  N   . ARG A 165 ? 0.36533 0.44947 0.38599 0.07315  -0.08862 0.01448  145 ARG A N   
2169 C  CA  . ARG A 165 ? 0.39900 0.47022 0.40640 0.08312  -0.09141 0.01722  145 ARG A CA  
2170 C  C   . ARG A 165 ? 0.39840 0.44582 0.37941 0.08229  -0.08361 0.01809  145 ARG A C   
2171 O  O   . ARG A 165 ? 0.39204 0.43111 0.36011 0.07518  -0.08170 0.01653  145 ARG A O   
2172 C  CB  . ARG A 165 ? 0.44831 0.51877 0.45114 0.08682  -0.10716 0.01862  145 ARG A CB  
2173 C  CG  . ARG A 165 ? 0.49947 0.59484 0.53116 0.08823  -0.11605 0.01843  145 ARG A CG  
2174 C  CD  . ARG A 165 ? 0.57297 0.66631 0.59921 0.09292  -0.13298 0.01988  145 ARG A CD  
2175 N  NE  . ARG A 165 ? 0.60642 0.68959 0.62320 0.10469  -0.13494 0.02359  145 ARG A NE  
2176 C  CZ  . ARG A 165 ? 0.75603 0.85323 0.79318 0.11364  -0.13774 0.02532  145 ARG A CZ  
2177 N  NH1 . ARG A 165 ? 0.74296 0.86703 0.81207 0.11232  -0.13759 0.02391  145 ARG A NH1 
2178 N  NH2 . ARG A 165 ? 0.74250 0.82659 0.76810 0.12441  -0.14045 0.02892  145 ARG A NH2 
2192 N  N   . PRO A 166 ? 0.37440 0.41065 0.34809 0.08939  -0.07896 0.02067  146 PRO A N   
2193 C  CA  . PRO A 166 ? 0.38168 0.39672 0.33307 0.08758  -0.07128 0.02235  146 PRO A CA  
2194 C  C   . PRO A 166 ? 0.37241 0.37404 0.30095 0.08486  -0.07604 0.02375  146 PRO A C   
2195 O  O   . PRO A 166 ? 0.38601 0.37879 0.30249 0.07895  -0.06899 0.02292  146 PRO A O   
2196 C  CB  . PRO A 166 ? 0.38351 0.38854 0.33201 0.09670  -0.07006 0.02585  146 PRO A CB  
2197 C  CG  . PRO A 166 ? 0.50551 0.52909 0.47872 0.10200  -0.07088 0.02365  146 PRO A CG  
2198 C  CD  . PRO A 166 ? 0.42933 0.47231 0.41683 0.09905  -0.07960 0.02193  146 PRO A CD  
2206 N  N   . GLU A 167 ? 0.38850 0.38897 0.31053 0.08952  -0.08828 0.02557  147 GLU A N   
2207 C  CA  . GLU A 167 ? 0.41862 0.40525 0.31557 0.08831  -0.09321 0.02659  147 GLU A CA  
2208 C  C   . GLU A 167 ? 0.38661 0.37903 0.28406 0.08032  -0.09595 0.02123  147 GLU A C   
2209 O  O   . GLU A 167 ? 0.44438 0.42460 0.31968 0.07926  -0.09853 0.02075  147 GLU A O   
2210 C  CB  . GLU A 167 ? 0.49944 0.48225 0.38785 0.09635  -0.10666 0.03006  147 GLU A CB  
2211 C  CG  . GLU A 167 ? 0.48776 0.48904 0.39580 0.09736  -0.12024 0.02724  147 GLU A CG  
2212 C  CD  . GLU A 167 ? 0.55938 0.57679 0.49462 0.10314  -0.12106 0.02819  147 GLU A CD  
2213 O  OE1 . GLU A 167 ? 0.46938 0.48660 0.41237 0.10457  -0.10975 0.02884  147 GLU A OE1 
2214 O  OE2 . GLU A 167 ? 0.55028 0.58122 0.49982 0.10658  -0.13353 0.02790  147 GLU A OE2 
2221 N  N   . GLN A 168 ? 0.40456 0.41374 0.32517 0.07474  -0.09445 0.01741  148 GLN A N   
2222 C  CA  . GLN A 168 ? 0.39453 0.40721 0.31662 0.06635  -0.09598 0.01272  148 GLN A CA  
2223 C  C   . GLN A 168 ? 0.39202 0.40346 0.31646 0.06004  -0.08260 0.01104  148 GLN A C   
2224 O  O   . GLN A 168 ? 0.38152 0.39442 0.30728 0.05315  -0.08282 0.00740  148 GLN A O   
2225 C  CB  . GLN A 168 ? 0.45404 0.48662 0.40101 0.06367  -0.10589 0.01063  148 GLN A CB  
2226 C  CG  . GLN A 168 ? 0.50770 0.54033 0.45041 0.06971  -0.12140 0.01186  148 GLN A CG  
2227 C  CD  . GLN A 168 ? 0.71897 0.77143 0.68657 0.06653  -0.13360 0.01000  148 GLN A CD  
2228 O  OE1 . GLN A 168 ? 0.55120 0.61599 0.53722 0.05842  -0.13089 0.00775  148 GLN A OE1 
2229 N  NE2 . GLN A 168 ? 0.57543 0.63140 0.54454 0.07286  -0.14754 0.01161  148 GLN A NE2 
2238 N  N   . ARG A 169 ? 0.35900 0.36633 0.28321 0.06230  -0.07177 0.01354  149 ARG A N   
2239 C  CA  . ARG A 169 ? 0.33058 0.33652 0.25662 0.05661  -0.06025 0.01201  149 ARG A CA  
2240 C  C   . ARG A 169 ? 0.36287 0.35630 0.27003 0.05287  -0.05819 0.01041  149 ARG A C   
2241 O  O   . ARG A 169 ? 0.33207 0.32805 0.24361 0.04665  -0.05447 0.00734  149 ARG A O   
2242 C  CB  . ARG A 169 ? 0.33135 0.33168 0.25703 0.06007  -0.05083 0.01483  149 ARG A CB  
2243 C  CG  . ARG A 169 ? 0.32154 0.33517 0.26768 0.06323  -0.04966 0.01463  149 ARG A CG  
2244 C  CD  . ARG A 169 ? 0.32968 0.33337 0.27168 0.06876  -0.04381 0.01724  149 ARG A CD  
2245 N  NE  . ARG A 169 ? 0.31456 0.32960 0.27400 0.07378  -0.04314 0.01632  149 ARG A NE  
2246 C  CZ  . ARG A 169 ? 0.34359 0.35106 0.30195 0.08079  -0.04141 0.01800  149 ARG A CZ  
2247 N  NH1 . ARG A 169 ? 0.35523 0.34376 0.29690 0.08241  -0.04014 0.02157  149 ARG A NH1 
2248 N  NH2 . ARG A 169 ? 0.39195 0.41095 0.36653 0.08632  -0.04059 0.01619  149 ARG A NH2 
2262 N  N   . ASP A 170 ? 0.36595 0.34564 0.25147 0.05707  -0.06018 0.01267  150 ASP A N   
2263 C  CA  . ASP A 170 ? 0.38764 0.35564 0.25394 0.05495  -0.05653 0.01118  150 ASP A CA  
2264 C  C   . ASP A 170 ? 0.39391 0.36440 0.25999 0.05089  -0.06428 0.00549  150 ASP A C   
2265 O  O   . ASP A 170 ? 0.40414 0.37051 0.26554 0.04696  -0.05938 0.00238  150 ASP A O   
2266 C  CB  . ASP A 170 ? 0.45350 0.40728 0.29559 0.06098  -0.05730 0.01540  150 ASP A CB  
2267 C  CG  . ASP A 170 ? 0.61941 0.56596 0.45778 0.06256  -0.04640 0.02113  150 ASP A CG  
2268 O  OD1 . ASP A 170 ? 0.71967 0.67055 0.57117 0.05851  -0.03792 0.02049  150 ASP A OD1 
2269 O  OD2 . ASP A 170 ? 0.70384 0.63973 0.52572 0.06762  -0.04699 0.02652  150 ASP A OD2 
2274 N  N   . MET A 171 ? 0.40310 0.38099 0.27692 0.05150  -0.07671 0.00402  151 MET A N   
2275 C  CA  A MET A 171 ? 0.41869 0.39917 0.29571 0.04655  -0.08574 -0.00138 151 MET A CA  
2276 C  CA  B MET A 171 ? 0.41869 0.39918 0.29572 0.04654  -0.08582 -0.00140 151 MET A CA  
2277 C  C   . MET A 171 ? 0.38438 0.37423 0.28081 0.03888  -0.08013 -0.00344 151 MET A C   
2278 O  O   . MET A 171 ? 0.38047 0.36468 0.27204 0.03447  -0.08016 -0.00743 151 MET A O   
2279 C  CB  A MET A 171 ? 0.43593 0.42529 0.32263 0.04806  -0.10039 -0.00160 151 MET A CB  
2280 C  CB  B MET A 171 ? 0.43554 0.42514 0.32267 0.04782  -0.10067 -0.00177 151 MET A CB  
2281 C  CG  A MET A 171 ? 0.46425 0.45504 0.35437 0.04265  -0.11178 -0.00689 151 MET A CG  
2282 C  CG  B MET A 171 ? 0.47519 0.45512 0.34209 0.05563  -0.10881 0.00025  151 MET A CG  
2283 S  SD  A MET A 171 ? 0.44558 0.44827 0.34907 0.04466  -0.12965 -0.00635 151 MET A SD  
2284 S  SD  B MET A 171 ? 0.45836 0.45193 0.34188 0.05764  -0.12681 0.00046  151 MET A SD  
2285 C  CE  A MET A 171 ? 0.50891 0.50097 0.38973 0.05602  -0.13200 -0.00187 151 MET A CE  
2286 C  CE  B MET A 171 ? 0.44926 0.44711 0.34235 0.04826  -0.13717 -0.00656 151 MET A CE  
2305 N  N   . PHE A 172 ? 0.36853 0.37193 0.28601 0.03777  -0.07515 -0.00069 152 PHE A N   
2306 C  CA  . PHE A 172 ? 0.32898 0.34160 0.26369 0.03074  -0.06975 -0.00178 152 PHE A CA  
2307 C  C   . PHE A 172 ? 0.33862 0.34171 0.26360 0.02907  -0.05850 -0.00231 152 PHE A C   
2308 O  O   . PHE A 172 ? 0.33077 0.33441 0.26071 0.02321  -0.05664 -0.00448 152 PHE A O   
2309 C  CB  . PHE A 172 ? 0.33380 0.36289 0.29051 0.03127  -0.06606 0.00118  152 PHE A CB  
2310 C  CG  . PHE A 172 ? 0.35446 0.39939 0.33049 0.02970  -0.07610 0.00141  152 PHE A CG  
2311 C  CD1 . PHE A 172 ? 0.36625 0.41208 0.34000 0.03502  -0.08652 0.00204  152 PHE A CD1 
2312 C  CD2 . PHE A 172 ? 0.39270 0.45206 0.38968 0.02270  -0.07502 0.00161  152 PHE A CD2 
2313 C  CE1 . PHE A 172 ? 0.38354 0.44561 0.37758 0.03338  -0.09636 0.00242  152 PHE A CE1 
2314 C  CE2 . PHE A 172 ? 0.37767 0.45372 0.39526 0.02065  -0.08347 0.00264  152 PHE A CE2 
2315 C  CZ  . PHE A 172 ? 0.37853 0.45665 0.39580 0.02600  -0.09434 0.00285  152 PHE A CZ  
2325 N  N   . LEU A 173 ? 0.32711 0.32133 0.23900 0.03397  -0.05138 0.00006  153 LEU A N   
2326 C  CA  . LEU A 173 ? 0.35408 0.34084 0.25894 0.03224  -0.04106 -0.00015 153 LEU A CA  
2327 C  C   . LEU A 173 ? 0.37580 0.35203 0.26546 0.03121  -0.04310 -0.00386 153 LEU A C   
2328 O  O   . LEU A 173 ? 0.38253 0.35669 0.27344 0.02777  -0.03764 -0.00565 153 LEU A O   
2329 C  CB  . LEU A 173 ? 0.38284 0.36279 0.27881 0.03690  -0.03354 0.00386  153 LEU A CB  
2330 C  CG  . LEU A 173 ? 0.38610 0.36231 0.28158 0.03455  -0.02255 0.00456  153 LEU A CG  
2331 C  CD1 . LEU A 173 ? 0.35145 0.33728 0.26425 0.02981  -0.01932 0.00329  153 LEU A CD1 
2332 C  CD2 . LEU A 173 ? 0.48782 0.45732 0.37657 0.03849  -0.01688 0.00928  153 LEU A CD2 
2344 N  N   . ARG A 174 ? 0.37368 0.34261 0.24814 0.03484  -0.05113 -0.00531 154 ARG A N   
2345 C  CA  . ARG A 174 ? 0.40872 0.36659 0.26683 0.03498  -0.05401 -0.01007 154 ARG A CA  
2346 C  C   . ARG A 174 ? 0.40283 0.36407 0.27291 0.02852  -0.06022 -0.01458 154 ARG A C   
2347 O  O   . ARG A 174 ? 0.41728 0.37208 0.28316 0.02665  -0.05670 -0.01776 154 ARG A O   
2348 C  CB  . ARG A 174 ? 0.49738 0.44641 0.33517 0.04067  -0.06256 -0.01096 154 ARG A CB  
2349 C  CG  . ARG A 174 ? 0.76627 0.70145 0.57872 0.04543  -0.05677 -0.01217 154 ARG A CG  
2350 C  CD  . ARG A 174 ? 0.89917 0.82553 0.70046 0.04492  -0.06317 -0.01965 154 ARG A CD  
2351 N  NE  . ARG A 174 ? 1.07854 0.99250 0.85446 0.05096  -0.05641 -0.02098 154 ARG A NE  
2352 C  CZ  . ARG A 174 ? 1.16823 1.07316 0.93295 0.05206  -0.05654 -0.02748 154 ARG A CZ  
2353 N  NH1 . ARG A 174 ? 1.03036 0.93511 0.80606 0.04698  -0.06424 -0.03320 154 ARG A NH1 
2354 N  NH2 . ARG A 174 ? 1.22216 1.11787 0.96439 0.05859  -0.04837 -0.02798 154 ARG A NH2 
2368 N  N   . TRP A 175 ? 0.37393 0.34569 0.26053 0.02493  -0.06914 -0.01438 155 TRP A N   
2369 C  CA  . TRP A 175 ? 0.37473 0.35065 0.27570 0.01736  -0.07444 -0.01711 155 TRP A CA  
2370 C  C   . TRP A 175 ? 0.34761 0.32719 0.25933 0.01314  -0.06388 -0.01555 155 TRP A C   
2371 O  O   . TRP A 175 ? 0.35972 0.33432 0.27282 0.00868  -0.06510 -0.01831 155 TRP A O   
2372 C  CB  . TRP A 175 ? 0.37118 0.36190 0.29303 0.01347  -0.08340 -0.01537 155 TRP A CB  
2373 C  CG  . TRP A 175 ? 0.37115 0.36067 0.28660 0.01692  -0.09573 -0.01665 155 TRP A CG  
2374 C  CD1 . TRP A 175 ? 0.40850 0.38295 0.29981 0.02164  -0.10243 -0.02056 155 TRP A CD1 
2375 C  CD2 . TRP A 175 ? 0.33753 0.34219 0.27077 0.01667  -0.10325 -0.01390 155 TRP A CD2 
2376 N  NE1 . TRP A 175 ? 0.44053 0.41900 0.33279 0.02396  -0.11505 -0.02042 155 TRP A NE1 
2377 C  CE2 . TRP A 175 ? 0.42892 0.42653 0.34816 0.02099  -0.11570 -0.01624 155 TRP A CE2 
2378 C  CE3 . TRP A 175 ? 0.35755 0.38158 0.31712 0.01370  -0.10046 -0.00977 155 TRP A CE3 
2379 C  CZ2 . TRP A 175 ? 0.48155 0.49133 0.41412 0.02221  -0.12618 -0.01437 155 TRP A CZ2 
2380 C  CZ3 . TRP A 175 ? 0.44764 0.48477 0.42116 0.01537  -0.10959 -0.00793 155 TRP A CZ3 
2381 C  CH2 . TRP A 175 ? 0.40756 0.43762 0.36830 0.01950  -0.12273 -0.01015 155 TRP A CH2 
2392 N  N   . SER A 176 ? 0.33406 0.32187 0.25381 0.01450  -0.05462 -0.01118 156 SER A N   
2393 C  CA  . SER A 176 ? 0.34830 0.33984 0.27725 0.01100  -0.04533 -0.00957 156 SER A CA  
2394 C  C   . SER A 176 ? 0.35551 0.33488 0.27085 0.01243  -0.03945 -0.01173 156 SER A C   
2395 O  O   . SER A 176 ? 0.35916 0.33744 0.27963 0.00839  -0.03706 -0.01258 156 SER A O   
2396 C  CB  . SER A 176 ? 0.30847 0.30866 0.24508 0.01349  -0.03783 -0.00553 156 SER A CB  
2397 O  OG  . SER A 176 ? 0.30770 0.32094 0.25901 0.01285  -0.04271 -0.00376 156 SER A OG  
2403 N  N   . ASP A 177 ? 0.35918 0.32981 0.25741 0.01848  -0.03683 -0.01209 157 ASP A N   
2404 C  CA  . ASP A 177 ? 0.37429 0.33519 0.26025 0.02081  -0.03028 -0.01385 157 ASP A CA  
2405 C  C   . ASP A 177 ? 0.40264 0.35502 0.28277 0.01935  -0.03661 -0.01936 157 ASP A C   
2406 O  O   . ASP A 177 ? 0.40615 0.35445 0.28663 0.01844  -0.03242 -0.02107 157 ASP A O   
2407 C  CB  . ASP A 177 ? 0.44347 0.39742 0.31160 0.02749  -0.02650 -0.01244 157 ASP A CB  
2408 C  CG  . ASP A 177 ? 0.55539 0.51417 0.42773 0.02912  -0.01917 -0.00663 157 ASP A CG  
2409 O  OD1 . ASP A 177 ? 0.46232 0.42851 0.34924 0.02606  -0.01468 -0.00434 157 ASP A OD1 
2410 O  OD2 . ASP A 177 ? 0.54327 0.49641 0.40165 0.03401  -0.01780 -0.00424 157 ASP A OD2 
2415 N  N   . ASP A 178 ? 0.37165 0.32064 0.24678 0.01926  -0.04764 -0.02241 158 ASP A N   
2416 C  CA  . ASP A 178 ? 0.44608 0.38479 0.31514 0.01768  -0.05562 -0.02840 158 ASP A CA  
2417 C  C   . ASP A 178 ? 0.46864 0.41154 0.35585 0.00997  -0.05693 -0.02790 158 ASP A C   
2418 O  O   . ASP A 178 ? 0.43047 0.36408 0.31429 0.00926  -0.05707 -0.03134 158 ASP A O   
2419 C  CB  . ASP A 178 ? 0.41912 0.35400 0.28127 0.01808  -0.06916 -0.03169 158 ASP A CB  
2420 C  CG  . ASP A 178 ? 0.51594 0.44305 0.35490 0.02637  -0.06933 -0.03273 158 ASP A CG  
2421 O  OD1 . ASP A 178 ? 0.58787 0.50916 0.41281 0.03191  -0.05937 -0.03240 158 ASP A OD1 
2422 O  OD2 . ASP A 178 ? 0.61578 0.54298 0.45088 0.02720  -0.07989 -0.03356 158 ASP A OD2 
2427 N  N   . LEU A 179 ? 0.38806 0.34461 0.29425 0.00448  -0.05827 -0.02350 159 LEU A N   
2428 C  CA  . LEU A 179 ? 0.37480 0.33635 0.29799 -0.00334 -0.05916 -0.02165 159 LEU A CA  
2429 C  C   . LEU A 179 ? 0.39830 0.35918 0.32328 -0.00329 -0.04877 -0.01976 159 LEU A C   
2430 O  O   . LEU A 179 ? 0.41489 0.36984 0.34285 -0.00694 -0.05020 -0.02073 159 LEU A O   
2431 C  CB  . LEU A 179 ? 0.38059 0.35920 0.32318 -0.00805 -0.06088 -0.01673 159 LEU A CB  
2432 C  CG  . LEU A 179 ? 0.43834 0.41893 0.38368 -0.00960 -0.07341 -0.01848 159 LEU A CG  
2433 C  CD1 . LEU A 179 ? 0.45349 0.45290 0.41663 -0.01101 -0.07397 -0.01370 159 LEU A CD1 
2434 C  CD2 . LEU A 179 ? 0.45798 0.43149 0.40812 -0.01674 -0.08326 -0.02115 159 LEU A CD2 
2446 N  N   . VAL A 180 ? 0.37140 0.33739 0.29480 0.00070  -0.03921 -0.01701 160 VAL A N   
2447 C  CA  . VAL A 180 ? 0.37780 0.34370 0.30387 0.00052  -0.03063 -0.01536 160 VAL A CA  
2448 C  C   . VAL A 180 ? 0.39471 0.34777 0.30783 0.00478  -0.02916 -0.01955 160 VAL A C   
2449 O  O   . VAL A 180 ? 0.41567 0.36581 0.33212 0.00360  -0.02644 -0.01957 160 VAL A O   
2450 C  CB  . VAL A 180 ? 0.37687 0.35091 0.30561 0.00305  -0.02207 -0.01167 160 VAL A CB  
2451 C  CG1 . VAL A 180 ? 0.38513 0.35318 0.30016 0.00957  -0.01772 -0.01266 160 VAL A CG1 
2452 C  CG2 . VAL A 180 ? 0.43277 0.41073 0.37005 0.00032  -0.01580 -0.00912 160 VAL A CG2 
2462 N  N   . THR A 181 ? 0.39894 0.34415 0.29673 0.01031  -0.03110 -0.02317 161 THR A N   
2463 C  CA  . THR A 181 ? 0.42521 0.35839 0.30986 0.01538  -0.02951 -0.02789 161 THR A CA  
2464 C  C   . THR A 181 ? 0.44391 0.36745 0.32983 0.01220  -0.03784 -0.03208 161 THR A C   
2465 O  O   . THR A 181 ? 0.44222 0.35850 0.32581 0.01450  -0.03530 -0.03446 161 THR A O   
2466 C  CB  . THR A 181 ? 0.46039 0.38710 0.32596 0.02241  -0.02953 -0.03068 161 THR A CB  
2467 O  OG1 . THR A 181 ? 0.50409 0.43791 0.36866 0.02526  -0.02045 -0.02587 161 THR A OG1 
2468 C  CG2 . THR A 181 ? 0.50438 0.41890 0.35565 0.02851  -0.02762 -0.03631 161 THR A CG2 
2476 N  N   . PHE A 182 ? 0.42357 0.34700 0.31471 0.00673  -0.04815 -0.03271 162 PHE A N   
2477 C  CA  . PHE A 182 ? 0.41340 0.32721 0.30809 0.00198  -0.05699 -0.03569 162 PHE A CA  
2478 C  C   . PHE A 182 ? 0.44284 0.35993 0.35119 -0.00274 -0.05276 -0.03145 162 PHE A C   
2479 O  O   . PHE A 182 ? 0.48148 0.38697 0.38822 -0.00299 -0.05567 -0.03410 162 PHE A O   
2480 C  CB  . PHE A 182 ? 0.43831 0.35542 0.34102 -0.00471 -0.06828 -0.03526 162 PHE A CB  
2481 C  CG  . PHE A 182 ? 0.45545 0.36332 0.36497 -0.01165 -0.07804 -0.03696 162 PHE A CG  
2482 C  CD1 . PHE A 182 ? 0.52341 0.41313 0.41936 -0.00931 -0.08750 -0.04472 162 PHE A CD1 
2483 C  CD2 . PHE A 182 ? 0.53203 0.44844 0.46059 -0.02041 -0.07766 -0.03062 162 PHE A CD2 
2484 C  CE1 . PHE A 182 ? 0.61185 0.49094 0.51453 -0.01626 -0.09737 -0.04618 162 PHE A CE1 
2485 C  CE2 . PHE A 182 ? 0.56493 0.47206 0.50028 -0.02757 -0.08640 -0.03094 162 PHE A CE2 
2486 C  CZ  . PHE A 182 ? 0.59774 0.48563 0.52081 -0.02581 -0.09676 -0.03876 162 PHE A CZ  
2496 N  N   . LEU A 183 ? 0.40262 0.33443 0.32351 -0.00616 -0.04662 -0.02500 163 LEU A N   
2497 C  CA  . LEU A 183 ? 0.36768 0.30333 0.29962 -0.01031 -0.04248 -0.02044 163 LEU A CA  
2498 C  C   . LEU A 183 ? 0.41526 0.34766 0.34202 -0.00443 -0.03453 -0.02122 163 LEU A C   
2499 O  O   . LEU A 183 ? 0.38001 0.31115 0.31295 -0.00668 -0.03313 -0.01875 163 LEU A O   
2500 C  CB  . LEU A 183 ? 0.39570 0.34795 0.34014 -0.01451 -0.03806 -0.01412 163 LEU A CB  
2501 C  CG  . LEU A 183 ? 0.40050 0.36181 0.35527 -0.02045 -0.04383 -0.01163 163 LEU A CG  
2502 C  CD1 . LEU A 183 ? 0.40183 0.37986 0.36583 -0.02099 -0.03722 -0.00668 163 LEU A CD1 
2503 C  CD2 . LEU A 183 ? 0.42271 0.38028 0.38657 -0.02847 -0.04996 -0.00940 163 LEU A CD2 
2515 N  N   . SER A 184 ? 0.43145 0.36331 0.34780 0.00281  -0.02935 -0.02387 164 SER A N   
2516 C  CA  . SER A 184 ? 0.43249 0.36468 0.34616 0.00847  -0.02075 -0.02394 164 SER A CA  
2517 C  C   . SER A 184 ? 0.42827 0.34770 0.33116 0.01503  -0.02137 -0.02982 164 SER A C   
2518 O  O   . SER A 184 ? 0.39722 0.31792 0.29790 0.02084  -0.01380 -0.03028 164 SER A O   
2519 C  CB  . SER A 184 ? 0.42370 0.36407 0.33389 0.01198  -0.01353 -0.02203 164 SER A CB  
2520 O  OG  . SER A 184 ? 0.40592 0.35800 0.32621 0.00789  -0.01065 -0.01687 164 SER A OG  
2526 N  N   . SER A 185 ? 0.44154 0.34877 0.33799 0.01456  -0.03027 -0.03457 165 SER A N   
2527 C  CA  . SER A 185 ? 0.52286 0.41638 0.40609 0.02225  -0.03122 -0.04154 165 SER A CA  
2528 C  C   . SER A 185 ? 0.64912 0.52780 0.52986 0.01903  -0.04320 -0.04596 165 SER A C   
2529 O  O   . SER A 185 ? 0.63435 0.51491 0.52570 0.01011  -0.04991 -0.04250 165 SER A O   
2530 C  CB  . SER A 185 ? 0.67984 0.57268 0.54694 0.02954  -0.02730 -0.04486 165 SER A CB  
2531 O  OG  . SER A 185 ? 0.58282 0.47310 0.44328 0.02680  -0.03551 -0.04647 165 SER A OG  
2537 N  N   . HIS A 186 ? 0.67475 0.53845 0.54174 0.02650  -0.04556 -0.05357 166 HIS A N   
2538 C  CA  . HIS A 186 ? 0.73347 0.57912 0.59412 0.02489  -0.05807 -0.05973 166 HIS A CA  
2539 C  C   . HIS A 186 ? 0.80133 0.63944 0.64188 0.03101  -0.06136 -0.06688 166 HIS A C   
2540 O  O   . HIS A 186 ? 0.86376 0.69512 0.68860 0.04162  -0.05612 -0.07263 166 HIS A O   
2541 C  CB  . HIS A 186 ? 0.75360 0.58545 0.61341 0.02957  -0.05903 -0.06349 166 HIS A CB  
2542 C  CG  . HIS A 186 ? 0.99226 0.80237 0.84412 0.02867  -0.07234 -0.07067 166 HIS A CG  
2543 N  ND1 . HIS A 186 ? 0.99327 0.78669 0.82546 0.03889  -0.07490 -0.08101 166 HIS A ND1 
2544 C  CD2 . HIS A 186 ? 0.99096 0.79263 0.85172 0.01865  -0.08401 -0.06902 166 HIS A CD2 
2545 C  CE1 . HIS A 186 ? 1.01829 0.79245 0.84713 0.03527  -0.08859 -0.08617 166 HIS A CE1 
2546 N  NE2 . HIS A 186 ? 1.00421 0.78323 0.85120 0.02246  -0.09439 -0.07858 166 HIS A NE2 
2549 N  N   . VAL A 187 ? 0.79162 0.63180 0.63256 0.02468  -0.06990 -0.06625 167 VAL A N   
2550 C  CA  . VAL A 187 ? 0.80232 0.63941 0.62470 0.03008  -0.07228 -0.07096 167 VAL A CA  
2551 C  C   . VAL A 187 ? 0.86549 0.68010 0.66823 0.03572  -0.08218 -0.08188 167 VAL A C   
2552 O  O   . VAL A 187 ? 0.76757 0.56864 0.57448 0.03187  -0.09174 -0.08539 167 VAL A O   
2553 C  CB  . VAL A 187 ? 0.81695 0.66501 0.64780 0.02206  -0.07878 -0.06643 167 VAL A CB  
2554 C  CG1 . VAL A 187 ? 0.69362 0.56271 0.54041 0.01859  -0.06825 -0.05677 167 VAL A CG1 
2555 C  CG2 . VAL A 187 ? 0.81453 0.65709 0.65810 0.01167  -0.09281 -0.06672 167 VAL A CG2 
2565 N  N   . SER A 188 ? 0.78323 0.59278 0.56309 0.04509  -0.08007 -0.08726 168 SER A N   
2566 C  CA  . SER A 188 ? 0.86357 0.65324 0.62265 0.05062  -0.09015 -0.09752 168 SER A CA  
2567 C  C   . SER A 188 ? 0.95207 0.73932 0.71720 0.04109  -0.10628 -0.09771 168 SER A C   
2568 O  O   . SER A 188 ? 0.88321 0.68176 0.66492 0.03124  -0.11041 -0.09178 168 SER A O   
2569 C  CB  . SER A 188 ? 0.85348 0.64580 0.59253 0.06164  -0.08082 -0.09875 168 SER A CB  
2570 O  OG  . SER A 188 ? 0.83523 0.63908 0.57148 0.05960  -0.07998 -0.09375 168 SER A OG  
2576 N  N   . GLN A 189 ? 0.85614 0.63102 0.61019 0.04405  -0.11471 -0.10358 169 GLN A N   
2577 C  CA  . GLN A 189 ? 0.88058 0.65381 0.64131 0.03540  -0.13015 -0.10377 169 GLN A CA  
2578 C  C   . GLN A 189 ? 0.88866 0.67480 0.64506 0.03540  -0.13018 -0.10014 169 GLN A C   
2579 O  O   . GLN A 189 ? 0.83272 0.62799 0.60441 0.02595  -0.13887 -0.09613 169 GLN A O   
2580 C  CB  . GLN A 189 ? 0.87733 0.63257 0.62616 0.03903  -0.13966 -0.11144 169 GLN A CB  
2581 C  CG  . GLN A 189 ? 0.88942 0.64256 0.64529 0.03044  -0.15612 -0.11196 169 GLN A CG  
2582 C  CD  . GLN A 189 ? 1.02822 0.78785 0.81191 0.01601  -0.16368 -0.10621 169 GLN A CD  
2583 O  OE1 . GLN A 189 ? 1.01582 0.77021 0.81025 0.01235  -0.16227 -0.10501 169 GLN A OE1 
2584 N  NE2 . GLN A 189 ? 0.95130 0.72328 0.74759 0.00786  -0.17143 -0.10197 169 GLN A NE2 
2587 N  N   . GLU A 190 ? 0.94183 0.72983 0.67877 0.04593  -0.12011 -0.10068 170 GLU A N   
2588 C  CA  . GLU A 190 ? 0.88812 0.68713 0.61968 0.04678  -0.11959 -0.09642 170 GLU A CA  
2589 C  C   . GLU A 190 ? 0.85664 0.67236 0.60474 0.04052  -0.11533 -0.08868 170 GLU A C   
2590 O  O   . GLU A 190 ? 0.79928 0.62464 0.55577 0.03520  -0.12257 -0.08489 170 GLU A O   
2591 C  CB  . GLU A 190 ? 0.86000 0.65777 0.56855 0.05878  -0.10766 -0.09694 170 GLU A CB  
2594 N  N   . ASP A 191 ? 0.71965 0.53925 0.47301 0.04148  -0.10390 -0.08635 171 ASP A N   
2595 C  CA  . ASP A 191 ? 0.71768 0.55768 0.49339 0.03537  -0.09587 -0.07610 171 ASP A CA  
2596 C  C   . ASP A 191 ? 0.67902 0.52618 0.48166 0.02295  -0.10464 -0.07245 171 ASP A C   
2597 O  O   . ASP A 191 ? 0.61818 0.48267 0.43887 0.01728  -0.10242 -0.06470 171 ASP A O   
2598 C  CB  . ASP A 191 ? 0.74059 0.58669 0.52048 0.03937  -0.07891 -0.07226 171 ASP A CB  
2599 C  CG  . ASP A 191 ? 0.88252 0.72945 0.64226 0.04975  -0.06716 -0.07170 171 ASP A CG  
2600 O  OD1 . ASP A 191 ? 0.92472 0.77189 0.67089 0.05253  -0.07030 -0.07116 171 ASP A OD1 
2601 O  OD2 . ASP A 191 ? 0.91510 0.76285 0.67307 0.05508  -0.05481 -0.07124 171 ASP A OD2 
2606 N  N   . PHE A 192 ? 0.64550 0.47936 0.45113 0.01873  -0.11449 -0.07767 172 PHE A N   
2607 C  CA  . PHE A 192 ? 0.60636 0.44651 0.43647 0.00621  -0.12413 -0.07373 172 PHE A CA  
2608 C  C   . PHE A 192 ? 0.60019 0.44601 0.43302 0.00217  -0.13677 -0.07371 172 PHE A C   
2609 O  O   . PHE A 192 ? 0.54519 0.40873 0.40081 -0.00583 -0.13778 -0.06633 172 PHE A O   
2610 C  CB  . PHE A 192 ? 0.62719 0.44897 0.45837 0.00241  -0.13318 -0.07928 172 PHE A CB  
2611 C  CG  . PHE A 192 ? 0.69130 0.51842 0.54741 -0.01127 -0.14326 -0.07458 172 PHE A CG  
2612 C  CD1 . PHE A 192 ? 0.76202 0.60250 0.64082 -0.01854 -0.13528 -0.06538 172 PHE A CD1 
2613 C  CD2 . PHE A 192 ? 0.76076 0.58037 0.61813 -0.01700 -0.16031 -0.07876 172 PHE A CD2 
2614 C  CE1 . PHE A 192 ? 0.76563 0.61235 0.66753 -0.03133 -0.14318 -0.05992 172 PHE A CE1 
2615 C  CE2 . PHE A 192 ? 0.78806 0.61485 0.67123 -0.03033 -0.16849 -0.07311 172 PHE A CE2 
2616 C  CZ  . PHE A 192 ? 0.74086 0.58107 0.64588 -0.03765 -0.15981 -0.06363 172 PHE A CZ  
2626 N  N   . GLN A 193 ? 0.60390 0.43563 0.41386 0.00826  -0.14610 -0.08178 173 GLN A N   
2627 C  CA  . GLN A 193 ? 0.53834 0.37726 0.35232 0.00565  -0.15666 -0.08064 173 GLN A CA  
2628 C  C   . GLN A 193 ? 0.55512 0.41212 0.37247 0.00749  -0.15095 -0.07398 173 GLN A C   
2629 O  O   . GLN A 193 ? 0.54433 0.41610 0.38091 0.00099  -0.15765 -0.06914 173 GLN A O   
2630 C  CB  . GLN A 193 ? 0.58492 0.40951 0.37609 0.01373  -0.16112 -0.08733 173 GLN A CB  
2631 C  CG  . GLN A 193 ? 0.59523 0.42484 0.39219 0.00994  -0.17482 -0.08699 173 GLN A CG  
2632 C  CD  . GLN A 193 ? 0.66412 0.49687 0.48726 -0.00276 -0.18710 -0.08573 173 GLN A CD  
2633 O  OE1 . GLN A 193 ? 0.71456 0.53261 0.53725 -0.00530 -0.19309 -0.09038 173 GLN A OE1 
2634 N  NE2 . GLN A 193 ? 0.68727 0.53970 0.53430 -0.01068 -0.19046 -0.07889 173 GLN A NE2 
2643 N  N   . ILE A 194 ? 0.55132 0.41023 0.35528 0.01620  -0.13571 -0.07175 174 ILE A N   
2644 C  CA  . ILE A 194 ? 0.57284 0.44915 0.38302 0.01822  -0.12705 -0.06363 174 ILE A CA  
2645 C  C   . ILE A 194 ? 0.55056 0.44632 0.39242 0.00954  -0.12174 -0.05528 174 ILE A C   
2646 O  O   . ILE A 194 ? 0.50235 0.41348 0.35745 0.00759  -0.12289 -0.04974 174 ILE A O   
2647 C  CB  . ILE A 194 ? 0.57967 0.45250 0.36990 0.02828  -0.11164 -0.06268 174 ILE A CB  
2648 C  CG1 . ILE A 194 ? 0.70321 0.55896 0.46037 0.03755  -0.11708 -0.07005 174 ILE A CG1 
2649 C  CG2 . ILE A 194 ? 0.67343 0.56302 0.47314 0.02917  -0.10172 -0.05358 174 ILE A CG2 
2650 C  CD1 . ILE A 194 ? 0.75319 0.60647 0.49085 0.04738  -0.10113 -0.06825 174 ILE A CD1 
2662 N  N   . THR A 195 ? 0.48085 0.37599 0.33451 0.00487  -0.11599 -0.05428 175 THR A N   
2663 C  CA  . THR A 195 ? 0.45685 0.36934 0.33802 -0.00314 -0.11078 -0.04651 175 THR A CA  
2664 C  C   . THR A 195 ? 0.44379 0.36522 0.34473 -0.01217 -0.12374 -0.04481 175 THR A C   
2665 O  O   . THR A 195 ? 0.41136 0.35183 0.33197 -0.01583 -0.12087 -0.03809 175 THR A O   
2666 C  CB  . THR A 195 ? 0.53010 0.43742 0.41690 -0.00605 -0.10387 -0.04605 175 THR A CB  
2667 O  OG1 . THR A 195 ? 0.58413 0.48469 0.45411 0.00273  -0.09247 -0.04779 175 THR A OG1 
2668 C  CG2 . THR A 195 ? 0.48798 0.41262 0.39906 -0.01308 -0.09696 -0.03776 175 THR A CG2 
2676 N  N   . MET A 196 ? 0.44337 0.35151 0.34072 -0.01602 -0.13790 -0.05084 176 MET A N   
2677 C  CA  . MET A 196 ? 0.43722 0.35424 0.35584 -0.02582 -0.15106 -0.04893 176 MET A CA  
2678 C  C   . MET A 196 ? 0.42873 0.35757 0.34856 -0.02276 -0.15718 -0.04768 176 MET A C   
2679 O  O   . MET A 196 ? 0.42875 0.37638 0.37333 -0.02915 -0.16087 -0.04211 176 MET A O   
2680 C  CB  . MET A 196 ? 0.52831 0.42570 0.44101 -0.03047 -0.16655 -0.05647 176 MET A CB  
2681 C  CG  . MET A 196 ? 0.63778 0.52563 0.55784 -0.03660 -0.16355 -0.05585 176 MET A CG  
2682 S  SD  . MET A 196 ? 0.94777 0.85727 0.89608 -0.04415 -0.14888 -0.04363 176 MET A SD  
2683 C  CE  . MET A 196 ? 0.82261 0.74983 0.80249 -0.05766 -0.16092 -0.03772 176 MET A CE  
2693 N  N   . ASP A 197 ? 0.44793 0.36586 0.34105 -0.01271 -0.15868 -0.05266 177 ASP A N   
2694 C  CA  . ASP A 197 ? 0.42765 0.35487 0.31950 -0.00885 -0.16541 -0.05121 177 ASP A CA  
2695 C  C   . ASP A 197 ? 0.39601 0.34441 0.30384 -0.00723 -0.15272 -0.04232 177 ASP A C   
2696 O  O   . ASP A 197 ? 0.41605 0.38022 0.34007 -0.00867 -0.15874 -0.03854 177 ASP A O   
2697 C  CB  . ASP A 197 ? 0.48063 0.39058 0.33755 0.00213  -0.16774 -0.05734 177 ASP A CB  
2698 C  CG  . ASP A 197 ? 0.53056 0.42062 0.37226 0.00222  -0.17739 -0.06586 177 ASP A CG  
2699 O  OD1 . ASP A 197 ? 0.55261 0.44148 0.41083 -0.00666 -0.18734 -0.06755 177 ASP A OD1 
2700 O  OD2 . ASP A 197 ? 0.62414 0.50041 0.43823 0.01174  -0.17296 -0.06991 177 ASP A OD2 
2705 N  N   . ALA A 198 ? 0.40109 0.34902 0.30322 -0.00333 -0.13618 -0.03958 178 ALA A N   
2706 C  CA  . ALA A 198 ? 0.37695 0.34208 0.29283 -0.00182 -0.12354 -0.03201 178 ALA A CA  
2707 C  C   . ALA A 198 ? 0.41220 0.39619 0.35969 -0.01087 -0.12375 -0.02678 178 ALA A C   
2708 O  O   . ALA A 198 ? 0.35338 0.35477 0.31681 -0.01038 -0.12317 -0.02201 178 ALA A O   
2709 C  CB  . ALA A 198 ? 0.42221 0.38162 0.32731 0.00238  -0.10753 -0.03085 178 ALA A CB  
2715 N  N   . PHE A 199 ? 0.35730 0.33806 0.31432 -0.01901 -0.12498 -0.02741 179 PHE A N   
2716 C  CA  . PHE A 199 ? 0.36413 0.36318 0.35082 -0.02825 -0.12483 -0.02151 179 PHE A CA  
2717 C  C   . PHE A 199 ? 0.32015 0.33174 0.32347 -0.03192 -0.13858 -0.02070 179 PHE A C   
2718 O  O   . PHE A 199 ? 0.33876 0.37219 0.36523 -0.03415 -0.13555 -0.01467 179 PHE A O   
2719 C  CB  . PHE A 199 ? 0.34447 0.33541 0.33711 -0.03691 -0.12520 -0.02167 179 PHE A CB  
2720 C  CG  . PHE A 199 ? 0.36279 0.37263 0.38518 -0.04698 -0.12445 -0.01448 179 PHE A CG  
2721 C  CD1 . PHE A 199 ? 0.37337 0.39739 0.40653 -0.04708 -0.11009 -0.00796 179 PHE A CD1 
2722 C  CD2 . PHE A 199 ? 0.38612 0.40077 0.42576 -0.05595 -0.13802 -0.01399 179 PHE A CD2 
2723 C  CE1 . PHE A 199 ? 0.36938 0.41233 0.42888 -0.05557 -0.10819 -0.00083 179 PHE A CE1 
2724 C  CE2 . PHE A 199 ? 0.39292 0.42744 0.46138 -0.06525 -0.13617 -0.00626 179 PHE A CE2 
2725 C  CZ  . PHE A 199 ? 0.37245 0.42119 0.45003 -0.06476 -0.12045 0.00047  179 PHE A CZ  
2735 N  N   . ALA A 200 ? 0.31895 0.31761 0.31128 -0.03222 -0.15411 -0.02693 180 ALA A N   
2736 C  CA  . ALA A 200 ? 0.32373 0.33359 0.33232 -0.03618 -0.16936 -0.02665 180 ALA A CA  
2737 C  C   . ALA A 200 ? 0.34397 0.36961 0.35665 -0.02832 -0.16689 -0.02307 180 ALA A C   
2738 O  O   . ALA A 200 ? 0.32872 0.37483 0.36676 -0.03171 -0.17240 -0.01893 180 ALA A O   
2739 C  CB  . ALA A 200 ? 0.36794 0.35746 0.35768 -0.03593 -0.18700 -0.03531 180 ALA A CB  
2745 N  N   . ALA A 201 ? 0.34180 0.35764 0.32992 -0.01765 -0.15936 -0.02454 181 ALA A N   
2746 C  CA  . ALA A 201 ? 0.37754 0.40503 0.36720 -0.00949 -0.15740 -0.02100 181 ALA A CA  
2747 C  C   . ALA A 201 ? 0.31150 0.36015 0.32468 -0.01019 -0.14386 -0.01389 181 ALA A C   
2748 O  O   . ALA A 201 ? 0.33982 0.40701 0.37173 -0.00831 -0.14671 -0.01015 181 ALA A O   
2749 C  CB  . ALA A 201 ? 0.37786 0.38768 0.33444 0.00122  -0.15207 -0.02349 181 ALA A CB  
2755 N  N   . TYR A 202 ? 0.32176 0.36780 0.33405 -0.01243 -0.12990 -0.01234 182 TYR A N   
2756 C  CA  . TYR A 202 ? 0.27109 0.33524 0.30286 -0.01319 -0.11693 -0.00638 182 TYR A CA  
2757 C  C   . TYR A 202 ? 0.28053 0.36577 0.34388 -0.02184 -0.12168 -0.00243 182 TYR A C   
2758 O  O   . TYR A 202 ? 0.27926 0.38528 0.36223 -0.01971 -0.11717 0.00215  182 TYR A O   
2759 C  CB  . TYR A 202 ? 0.30294 0.35829 0.32589 -0.01460 -0.10326 -0.00600 182 TYR A CB  
2760 C  CG  . TYR A 202 ? 0.27886 0.35223 0.32005 -0.01518 -0.09099 -0.00040 182 TYR A CG  
2761 C  CD1 . TYR A 202 ? 0.30441 0.38230 0.34205 -0.00657 -0.08260 0.00120  182 TYR A CD1 
2762 C  CD2 . TYR A 202 ? 0.29464 0.38009 0.35605 -0.02408 -0.08839 0.00338  182 TYR A CD2 
2763 C  CE1 . TYR A 202 ? 0.31763 0.41081 0.36983 -0.00588 -0.07174 0.00524  182 TYR A CE1 
2764 C  CE2 . TYR A 202 ? 0.27984 0.38203 0.35560 -0.02358 -0.07638 0.00836  182 TYR A CE2 
2765 C  CZ  . TYR A 202 ? 0.28019 0.38586 0.35069 -0.01409 -0.06843 0.00863  182 TYR A CZ  
2766 O  OH  . TYR A 202 ? 0.32558 0.44677 0.40849 -0.01224 -0.05754 0.01236  182 TYR A OH  
2776 N  N   . ASN A 203 ? 0.25356 0.33378 0.32287 -0.03169 -0.13037 -0.00391 183 ASN A N   
2777 C  CA  . ASN A 203 ? 0.29382 0.39372 0.39455 -0.04165 -0.13600 0.00058  183 ASN A CA  
2778 C  C   . ASN A 203 ? 0.29202 0.40957 0.40954 -0.03883 -0.14618 0.00179  183 ASN A C   
2779 O  O   . ASN A 203 ? 0.30883 0.45176 0.45511 -0.04151 -0.14311 0.00765  183 ASN A O   
2780 C  CB  . ASN A 203 ? 0.30296 0.38890 0.40317 -0.05222 -0.14700 -0.00230 183 ASN A CB  
2781 C  CG  . ASN A 203 ? 0.31957 0.42446 0.45274 -0.06402 -0.15351 0.00301  183 ASN A CG  
2782 O  OD1 . ASN A 203 ? 0.36266 0.48242 0.51408 -0.06939 -0.14246 0.00989  183 ASN A OD1 
2783 N  ND2 . ASN A 203 ? 0.31846 0.42277 0.45943 -0.06863 -0.17169 0.00012  183 ASN A ND2 
2790 N  N   . ASP A 204 ? 0.28668 0.39156 0.38747 -0.03382 -0.15963 -0.00367 184 ASP A N   
2791 C  CA  . ASP A 204 ? 0.31159 0.43141 0.42668 -0.03065 -0.17166 -0.00285 184 ASP A CA  
2792 C  C   . ASP A 204 ? 0.28831 0.42570 0.41252 -0.02113 -0.16060 0.00176  184 ASP A C   
2793 O  O   . ASP A 204 ? 0.31641 0.47902 0.46988 -0.02186 -0.16269 0.00618  184 ASP A O   
2794 C  CB  . ASP A 204 ? 0.31163 0.41040 0.39922 -0.02505 -0.18639 -0.00976 184 ASP A CB  
2795 C  CG  . ASP A 204 ? 0.33817 0.45012 0.43869 -0.02199 -0.20160 -0.00931 184 ASP A CG  
2796 O  OD1 . ASP A 204 ? 0.37581 0.50025 0.50009 -0.03045 -0.21179 -0.00848 184 ASP A OD1 
2797 O  OD2 . ASP A 204 ? 0.42587 0.53558 0.51236 -0.01060 -0.20108 -0.00925 184 ASP A OD2 
2802 N  N   . PHE A 205 ? 0.29814 0.42224 0.39805 -0.01188 -0.14937 0.00064  185 PHE A N   
2803 C  CA  . PHE A 205 ? 0.29050 0.42673 0.39565 -0.00211 -0.13946 0.00418  185 PHE A CA  
2804 C  C   . PHE A 205 ? 0.29401 0.45366 0.42705 -0.00584 -0.12744 0.00951  185 PHE A C   
2805 O  O   . PHE A 205 ? 0.30061 0.48206 0.45551 -0.00147 -0.12669 0.01292  185 PHE A O   
2806 C  CB  . PHE A 205 ? 0.35020 0.46600 0.42499 0.00597  -0.12888 0.00235  185 PHE A CB  
2807 C  CG  . PHE A 205 ? 0.36479 0.48904 0.44290 0.01566  -0.11871 0.00549  185 PHE A CG  
2808 C  CD1 . PHE A 205 ? 0.40090 0.53446 0.48907 0.01512  -0.10346 0.00813  185 PHE A CD1 
2809 C  CD2 . PHE A 205 ? 0.42817 0.54956 0.49807 0.02553  -0.12482 0.00569  185 PHE A CD2 
2810 C  CE1 . PHE A 205 ? 0.40430 0.54391 0.49475 0.02453  -0.09498 0.01005  185 PHE A CE1 
2811 C  CE2 . PHE A 205 ? 0.43031 0.55735 0.50322 0.03470  -0.11604 0.00836  185 PHE A CE2 
2812 C  CZ  . PHE A 205 ? 0.38171 0.51798 0.46549 0.03415  -0.10158 0.01010  185 PHE A CZ  
2822 N  N   . THR A 206 ? 0.28810 0.44381 0.42060 -0.01351 -0.11830 0.01037  186 THR A N   
2823 C  CA  . THR A 206 ? 0.29004 0.46537 0.44326 -0.01614 -0.10465 0.01564  186 THR A CA  
2824 C  C   . THR A 206 ? 0.24821 0.44982 0.43615 -0.02354 -0.11044 0.02026  186 THR A C   
2825 O  O   . THR A 206 ? 0.30157 0.52686 0.51113 -0.02065 -0.10194 0.02476  186 THR A O   
2826 C  CB  . THR A 206 ? 0.26335 0.42604 0.40497 -0.02237 -0.09461 0.01579  186 THR A CB  
2827 O  OG1 . THR A 206 ? 0.27755 0.41745 0.38922 -0.01564 -0.08988 0.01164  186 THR A OG1 
2828 C  CG2 . THR A 206 ? 0.26594 0.44711 0.42391 -0.02348 -0.07965 0.02117  186 THR A CG2 
2836 N  N   . ARG A 207 ? 0.25783 0.45663 0.45274 -0.03268 -0.12539 0.01914  187 ARG A N   
2837 C  CA  . ARG A 207 ? 0.26381 0.48925 0.49510 -0.04089 -0.13147 0.02430  187 ARG A CA  
2838 C  C   . ARG A 207 ? 0.26958 0.51485 0.51812 -0.03252 -0.13814 0.02517  187 ARG A C   
2839 O  O   . ARG A 207 ? 0.30439 0.57916 0.58623 -0.03479 -0.13581 0.03082  187 ARG A O   
2840 C  CB  . ARG A 207 ? 0.32893 0.54444 0.56370 -0.05359 -0.14717 0.02257  187 ARG A CB  
2841 C  CG  . ARG A 207 ? 0.30275 0.50823 0.53429 -0.06427 -0.13958 0.02477  187 ARG A CG  
2842 C  CD  . ARG A 207 ? 0.37167 0.56011 0.60023 -0.07525 -0.15583 0.02142  187 ARG A CD  
2843 N  NE  . ARG A 207 ? 0.35194 0.52632 0.57360 -0.08405 -0.14941 0.02302  187 ARG A NE  
2844 C  CZ  . ARG A 207 ? 0.34174 0.53024 0.58717 -0.09539 -0.14383 0.03093  187 ARG A CZ  
2845 N  NH1 . ARG A 207 ? 0.36390 0.58139 0.64087 -0.09888 -0.14105 0.03762  187 ARG A NH1 
2846 N  NH2 . ARG A 207 ? 0.36743 0.53881 0.60223 -0.10225 -0.13945 0.03193  187 ARG A NH2 
2860 N  N   . ALA A 208 ? 0.31175 0.54198 0.53863 -0.02246 -0.14622 0.02015  188 ALA A N   
2861 C  CA  . ALA A 208 ? 0.32557 0.57230 0.56541 -0.01212 -0.15108 0.02122  188 ALA A CA  
2862 C  C   . ALA A 208 ? 0.28470 0.54729 0.53361 -0.00316 -0.13311 0.02477  188 ALA A C   
2863 O  O   . ALA A 208 ? 0.30670 0.59656 0.58435 0.00073  -0.13263 0.02850  188 ALA A O   
2864 C  CB  . ALA A 208 ? 0.36906 0.59281 0.57894 -0.00285 -0.16189 0.01589  188 ALA A CB  
2870 N  N   . THR A 209 ? 0.31685 0.56293 0.54205 0.00054  -0.11871 0.02333  189 THR A N   
2871 C  CA  . THR A 209 ? 0.34949 0.60724 0.57988 0.00913  -0.10205 0.02557  189 THR A CA  
2872 C  C   . THR A 209 ? 0.31678 0.60298 0.57856 0.00252  -0.09269 0.03128  189 THR A C   
2873 O  O   . THR A 209 ? 0.30777 0.61755 0.59061 0.00974  -0.08647 0.03404  189 THR A O   
2874 C  CB  . THR A 209 ? 0.40309 0.63682 0.60266 0.01222  -0.08987 0.02280  189 THR A CB  
2875 O  OG1 . THR A 209 ? 0.32058 0.52885 0.49141 0.01797  -0.09718 0.01848  189 THR A OG1 
2876 C  CG2 . THR A 209 ? 0.35177 0.59567 0.55523 0.02159  -0.07418 0.02411  189 THR A CG2 
2884 N  N   . ILE A 210 ? 0.29701 0.58092 0.56164 -0.01081 -0.09103 0.03341  190 ILE A N   
2885 C  CA  . ILE A 210 ? 0.36002 0.67048 0.65428 -0.01893 -0.08253 0.04024  190 ILE A CA  
2886 C  C   . ILE A 210 ? 0.36070 0.70186 0.69124 -0.01888 -0.09051 0.04403  190 ILE A C   
2887 O  O   . ILE A 210 ? 0.34708 0.71610 0.70188 -0.01531 -0.07957 0.04879  190 ILE A O   
2888 C  CB  . ILE A 210 ? 0.34580 0.64580 0.63786 -0.03454 -0.08474 0.04225  190 ILE A CB  
2889 C  CG1 . ILE A 210 ? 0.35954 0.63237 0.61854 -0.03370 -0.07529 0.03911  190 ILE A CG1 
2890 C  CG2 . ILE A 210 ? 0.42513 0.75302 0.74933 -0.04432 -0.07712 0.05081  190 ILE A CG2 
2891 C  CD1 . ILE A 210 ? 0.38005 0.63790 0.63311 -0.04740 -0.07890 0.04019  190 ILE A CD1 
2903 N  N   . ALA A 211 ? 0.31253 0.65008 0.64818 -0.02286 -0.10991 0.04197  191 ALA A N   
2904 C  CA  . ALA A 211 ? 0.35339 0.71603 0.72021 -0.02348 -0.11750 0.04391  191 ALA A CA  
2905 C  C   . ALA A 211 ? 0.35811 0.73730 0.73393 -0.00732 -0.11284 0.04359  191 ALA A C   
2906 O  O   . ALA A 211 ? 0.33045 0.73475 0.73194 -0.00514 -0.10639 0.04571  191 ALA A O   
2907 C  CB  . ALA A 211 ? 0.37763 0.72576 0.73793 -0.02871 -0.13858 0.03908  191 ALA A CB  
2913 N  N   . ALA A 212 ? 0.33902 0.70098 0.69093 0.00460  -0.11547 0.04005  192 ALA A N   
2914 C  CA  . ALA A 212 ? 0.36570 0.73869 0.72273 0.02101  -0.11154 0.03948  192 ALA A CA  
2915 C  C   . ALA A 212 ? 0.33031 0.72014 0.69692 0.02673  -0.09003 0.04225  192 ALA A C   
2916 O  O   . ALA A 212 ? 0.37196 0.78370 0.75971 0.03564  -0.08493 0.04301  192 ALA A O   
2917 C  CB  . ALA A 212 ? 0.34862 0.68961 0.66808 0.03147  -0.11604 0.03366  192 ALA A CB  
2923 N  N   . ARG A 213 ? 0.33772 0.71213 0.68353 0.02241  -0.07649 0.04167  193 ARG A N   
2924 C  CA  . ARG A 213 ? 0.34625 0.73383 0.69645 0.02863  -0.05650 0.04349  193 ARG A CA  
2925 C  C   . ARG A 213 ? 0.37538 0.79384 0.75829 0.02034  -0.04833 0.04990  193 ARG A C   
2926 O  O   . ARG A 213 ? 0.40249 0.83584 0.79450 0.02818  -0.03386 0.05019  193 ARG A O   
2927 C  CB  . ARG A 213 ? 0.31410 0.67492 0.63108 0.02675  -0.04555 0.04069  193 ARG A CB  
2928 C  CG  . ARG A 213 ? 0.34341 0.67179 0.62635 0.03429  -0.05065 0.03437  193 ARG A CG  
2929 C  CD  . ARG A 213 ? 0.33736 0.66752 0.61894 0.05103  -0.04921 0.03169  193 ARG A CD  
2930 N  NE  . ARG A 213 ? 0.42582 0.72346 0.67388 0.05675  -0.05298 0.02682  193 ARG A NE  
2931 C  CZ  . ARG A 213 ? 0.35061 0.63420 0.58836 0.05892  -0.06766 0.02515  193 ARG A CZ  
2932 N  NH1 . ARG A 213 ? 0.43482 0.73335 0.69272 0.05731  -0.08146 0.02704  193 ARG A NH1 
2933 N  NH2 . ARG A 213 ? 0.46654 0.72058 0.67286 0.06253  -0.06870 0.02180  193 ARG A NH2 
2947 N  N   . ARG A 214 ? 0.38800 0.80675 0.78096 0.00458  -0.05643 0.05244  194 ARG A N   
2948 C  CA  . ARG A 214 ? 0.46250 0.90261 0.88118 -0.00355 -0.04936 0.05647  194 ARG A CA  
2949 C  C   . ARG A 214 ? 0.34429 0.80644 0.78801 0.00462  -0.05273 0.05504  194 ARG A C   
2950 O  O   . ARG A 214 ? 0.41380 0.89762 0.87794 0.00429  -0.04121 0.05791  194 ARG A O   
2951 C  CB  . ARG A 214 ? 0.47141 0.90476 0.89488 -0.02173 -0.05930 0.05903  194 ARG A CB  
2952 C  CG  . ARG A 214 ? 0.56291 0.98272 0.97082 -0.03182 -0.05011 0.06260  194 ARG A CG  
2953 C  CD  . ARG A 214 ? 0.49091 0.90043 0.90238 -0.04905 -0.06119 0.06454  194 ARG A CD  
2954 N  NE  . ARG A 214 ? 0.49696 0.88832 0.88949 -0.05740 -0.05524 0.06703  194 ARG A NE  
2955 C  CZ  . ARG A 214 ? 0.40334 0.80081 0.79570 -0.06050 -0.03830 0.07250  194 ARG A CZ  
2956 N  NH1 . ARG A 214 ? 0.58895 1.00969 0.99786 -0.05586 -0.02474 0.07582  194 ARG A NH1 
2957 N  NH2 . ARG A 214 ? 0.44902 0.82797 0.82300 -0.06804 -0.03510 0.07448  194 ARG A NH2 
2971 N  N   . ALA A 215 ? 0.46412 0.92109 0.90600 0.01233  -0.06832 0.05077  195 ALA A N   
2972 C  CA  . ALA A 215 ? 0.44344 0.92082 0.90868 0.02080  -0.07324 0.04904  195 ALA A CA  
2973 C  C   . ALA A 215 ? 0.49312 0.97397 0.95499 0.03973  -0.06402 0.04628  195 ALA A C   
2974 O  O   . ALA A 215 ? 0.38529 0.88792 0.86921 0.04662  -0.05717 0.04615  195 ALA A O   
2975 C  CB  . ALA A 215 ? 0.42387 0.89384 0.88827 0.01938  -0.09616 0.04588  195 ALA A CB  
2981 N  N   . ASP A 216 ? 0.39697 0.85599 0.83147 0.04843  -0.06385 0.04395  196 ASP A N   
2982 C  CA  . ASP A 216 ? 0.46346 0.91994 0.88997 0.06642  -0.05532 0.04102  196 ASP A CA  
2983 C  C   . ASP A 216 ? 0.41024 0.84905 0.80836 0.06794  -0.04243 0.04079  196 ASP A C   
2984 O  O   . ASP A 216 ? 0.36728 0.78439 0.74011 0.07172  -0.04853 0.03889  196 ASP A O   
2985 C  CB  . ASP A 216 ? 0.44926 0.89546 0.87011 0.07767  -0.07169 0.03779  196 ASP A CB  
2988 N  N   . PRO A 217 ? 0.37278 0.82034 0.77308 0.06486  -0.02460 0.04254  197 PRO A N   
2989 C  CA  . PRO A 217 ? 0.46476 0.89596 0.83749 0.06622  -0.01247 0.04156  197 PRO A CA  
2990 C  C   . PRO A 217 ? 0.39816 0.81491 0.75119 0.08387  -0.00904 0.03594  197 PRO A C   
2991 O  O   . PRO A 217 ? 0.38771 0.81172 0.75098 0.09609  -0.00734 0.03339  197 PRO A O   
2992 C  CB  . PRO A 217 ? 0.42599 0.87165 0.80729 0.06134  0.00540  0.04437  197 PRO A CB  
2993 C  CG  . PRO A 217 ? 0.41688 0.88667 0.83058 0.05527  0.00258  0.04763  197 PRO A CG  
2994 C  CD  . PRO A 217 ? 0.44744 0.91980 0.87462 0.05834  -0.01598 0.04584  197 PRO A CD  
3002 N  N   . THR A 218 ? 0.36086 0.74913 0.68146 0.08352  -0.00806 0.03259  198 THR A N   
3003 C  CA  . THR A 218 ? 0.39720 0.76336 0.69328 0.09743  -0.00416 0.02644  198 THR A CA  
3004 C  C   . THR A 218 ? 0.41609 0.76941 0.69037 0.09554  0.01075  0.02425  198 THR A C   
3005 O  O   . THR A 218 ? 0.42176 0.79164 0.70589 0.08804  0.02091  0.02801  198 THR A O   
3006 C  CB  . THR A 218 ? 0.33919 0.67526 0.61251 0.09785  -0.01872 0.02351  198 THR A CB  
3007 O  OG1 . THR A 218 ? 0.40693 0.72183 0.65911 0.08434  -0.02070 0.02348  198 THR A OG1 
3008 C  CG2 . THR A 218 ? 0.41098 0.75909 0.70399 0.09875  -0.03501 0.02589  198 THR A CG2 
3016 N  N   . ASP A 219 ? 0.46721 0.79118 0.71210 0.10185  0.01185  0.01870  199 ASP A N   
3017 C  CA  . ASP A 219 ? 0.50818 0.81803 0.73114 0.10002  0.02399  0.01607  199 ASP A CA  
3018 C  C   . ASP A 219 ? 0.47584 0.75650 0.67285 0.08930  0.01859  0.01505  199 ASP A C   
3019 O  O   . ASP A 219 ? 0.51981 0.78259 0.69486 0.08950  0.02562  0.01177  199 ASP A O   
3020 C  CB  . ASP A 219 ? 0.66781 0.96805 0.87838 0.11599  0.03138  0.00991  199 ASP A CB  
3021 C  CG  . ASP A 219 ? 0.69632 0.99321 0.89231 0.11611  0.04596  0.00748  199 ASP A CG  
3022 O  OD1 . ASP A 219 ? 0.69410 0.99775 0.89067 0.10409  0.05093  0.01145  199 ASP A OD1 
3023 O  OD2 . ASP A 219 ? 0.80002 1.08589 0.98273 0.12833  0.05171  0.00149  199 ASP A OD2 
3028 N  N   . ASP A 220 ? 0.39062 0.66668 0.58999 0.08017  0.00620  0.01758  200 ASP A N   
3029 C  CA  . ASP A 220 ? 0.39691 0.64660 0.57273 0.07103  0.00125  0.01648  200 ASP A CA  
3030 C  C   . ASP A 220 ? 0.32552 0.58023 0.50293 0.05756  0.00631  0.01979  200 ASP A C   
3031 O  O   . ASP A 220 ? 0.30949 0.58741 0.50519 0.05495  0.01404  0.02351  200 ASP A O   
3032 C  CB  . ASP A 220 ? 0.34644 0.58618 0.52002 0.06895  -0.01421 0.01684  200 ASP A CB  
3033 C  CG  . ASP A 220 ? 0.39069 0.64964 0.58696 0.06001  -0.02280 0.02104  200 ASP A CG  
3034 O  OD1 . ASP A 220 ? 0.39138 0.67422 0.60925 0.05533  -0.01678 0.02470  200 ASP A OD1 
3035 O  OD2 . ASP A 220 ? 0.44094 0.69058 0.63306 0.05765  -0.03617 0.02082  200 ASP A OD2 
3040 N  N   . LEU A 221 ? 0.32525 0.55760 0.48284 0.04943  0.00253  0.01878  201 LEU A N   
3041 C  CA  . LEU A 221 ? 0.26243 0.49403 0.41676 0.03797  0.00759  0.02138  201 LEU A CA  
3042 C  C   . LEU A 221 ? 0.28907 0.54015 0.46657 0.02759  0.00312  0.02696  201 LEU A C   
3043 O  O   . LEU A 221 ? 0.26636 0.53072 0.45315 0.02124  0.01117  0.03127  201 LEU A O   
3044 C  CB  . LEU A 221 ? 0.27340 0.47691 0.40291 0.03278  0.00338  0.01875  201 LEU A CB  
3045 C  CG  . LEU A 221 ? 0.25550 0.45586 0.38079 0.02140  0.00719  0.02140  201 LEU A CG  
3046 C  CD1 . LEU A 221 ? 0.24367 0.45065 0.36642 0.02339  0.02031  0.02223  201 LEU A CD1 
3047 C  CD2 . LEU A 221 ? 0.34176 0.51526 0.44421 0.01766  0.00230  0.01840  201 LEU A CD2 
3059 N  N   . VAL A 222 ? 0.25844 0.51041 0.44466 0.02513  -0.01015 0.02726  202 VAL A N   
3060 C  CA  . VAL A 222 ? 0.25448 0.52435 0.46427 0.01441  -0.01598 0.03235  202 VAL A CA  
3061 C  C   . VAL A 222 ? 0.24727 0.54963 0.48546 0.01723  -0.00763 0.03698  202 VAL A C   
3062 O  O   . VAL A 222 ? 0.26148 0.58075 0.51748 0.00740  -0.00395 0.04294  202 VAL A O   
3063 C  CB  . VAL A 222 ? 0.24847 0.51292 0.46157 0.01226  -0.03323 0.03091  202 VAL A CB  
3064 C  CG1 . VAL A 222 ? 0.28077 0.56732 0.52325 0.00208  -0.04010 0.03609  202 VAL A CG1 
3065 C  CG2 . VAL A 222 ? 0.33194 0.56567 0.51706 0.00771  -0.03966 0.02705  202 VAL A CG2 
3075 N  N   . SER A 223 ? 0.25989 0.57181 0.50358 0.03088  -0.00444 0.03470  203 SER A N   
3076 C  CA  . SER A 223 ? 0.25248 0.59665 0.52348 0.03542  0.00466  0.03866  203 SER A CA  
3077 C  C   . SER A 223 ? 0.22042 0.57123 0.48771 0.03266  0.02127  0.04152  203 SER A C   
3078 O  O   . SER A 223 ? 0.25122 0.62854 0.54216 0.02749  0.02820  0.04804  203 SER A O   
3079 C  CB  . SER A 223 ? 0.30902 0.65789 0.58210 0.05253  0.00601  0.03455  203 SER A CB  
3080 O  OG  . SER A 223 ? 0.31378 0.66150 0.59439 0.05551  -0.00934 0.03343  203 SER A OG  
3086 N  N   . VAL A 224 ? 0.28958 0.61747 0.52775 0.03647  0.02789  0.03704  204 VAL A N   
3087 C  CA  . VAL A 224 ? 0.27764 0.60934 0.50825 0.03480  0.04281  0.03922  204 VAL A CA  
3088 C  C   . VAL A 224 ? 0.29437 0.62710 0.52895 0.01841  0.04216  0.04584  204 VAL A C   
3089 O  O   . VAL A 224 ? 0.27626 0.62645 0.52072 0.01392  0.05307  0.05199  204 VAL A O   
3090 C  CB  . VAL A 224 ? 0.35671 0.66145 0.55494 0.04207  0.04721  0.03234  204 VAL A CB  
3091 C  CG1 . VAL A 224 ? 0.39610 0.69810 0.58106 0.03725  0.05887  0.03457  204 VAL A CG1 
3092 C  CG2 . VAL A 224 ? 0.39206 0.69921 0.58879 0.05877  0.05116  0.02672  204 VAL A CG2 
3102 N  N   . LEU A 225 ? 0.24295 0.55579 0.46845 0.00962  0.02971  0.04481  205 LEU A N   
3103 C  CA  . LEU A 225 ? 0.24500 0.55482 0.47244 -0.00545 0.02795  0.05044  205 LEU A CA  
3104 C  C   . LEU A 225 ? 0.27622 0.61299 0.53699 -0.01442 0.02507  0.05814  205 LEU A C   
3105 O  O   . LEU A 225 ? 0.26943 0.61553 0.53917 -0.02491 0.03080  0.06559  205 LEU A O   
3106 C  CB  . LEU A 225 ? 0.21641 0.49738 0.42498 -0.01076 0.01532  0.04624  205 LEU A CB  
3107 C  CG  . LEU A 225 ? 0.22119 0.47633 0.39870 -0.00520 0.01909  0.04045  205 LEU A CG  
3108 C  CD1 . LEU A 225 ? 0.26236 0.49176 0.42381 -0.01028 0.00712  0.03681  205 LEU A CD1 
3109 C  CD2 . LEU A 225 ? 0.26042 0.51339 0.42661 -0.00795 0.03129  0.04330  205 LEU A CD2 
3121 N  N   . VAL A 226 ? 0.27598 0.62583 0.55617 -0.01071 0.01595  0.05704  206 VAL A N   
3122 C  CA  . VAL A 226 ? 0.25475 0.63219 0.56995 -0.01944 0.01208  0.06437  206 VAL A CA  
3123 C  C   . VAL A 226 ? 0.26448 0.66615 0.59462 -0.01783 0.02860  0.06989  206 VAL A C   
3124 O  O   . VAL A 226 ? 0.30457 0.71535 0.65064 -0.02875 0.02977  0.07565  206 VAL A O   
3125 C  CB  . VAL A 226 ? 0.26099 0.64786 0.59346 -0.01397 -0.00151 0.06143  206 VAL A CB  
3126 C  CG1 . VAL A 226 ? 0.35633 0.77188 0.72258 -0.01703 -0.00032 0.06626  206 VAL A CG1 
3127 C  CG2 . VAL A 226 ? 0.24200 0.60392 0.56203 -0.02127 -0.01983 0.05749  206 VAL A CG2 
3137 N  N   . SER A 227 ? 0.28649 0.69121 0.60598 -0.00380 0.04108  0.06622  207 SER A N   
3138 C  CA  . SER A 227 ? 0.33905 0.75880 0.66513 -0.00006 0.05652  0.06846  207 SER A CA  
3139 C  C   . SER A 227 ? 0.31937 0.73001 0.62573 -0.00476 0.06933  0.07179  207 SER A C   
3140 O  O   . SER A 227 ? 0.31245 0.73510 0.62386 -0.00450 0.08163  0.07515  207 SER A O   
3141 C  CB  . SER A 227 ? 0.38367 0.80885 0.70680 0.01823  0.06275  0.06181  207 SER A CB  
3142 O  OG  . SER A 227 ? 0.60528 1.04296 0.95081 0.02274  0.05239  0.06003  207 SER A OG  
3148 N  N   . SER A 228 ? 0.25516 0.64529 0.53953 -0.00907 0.06630  0.07112  208 SER A N   
3149 C  CA  . SER A 228 ? 0.22931 0.60821 0.49214 -0.01249 0.07705  0.07370  208 SER A CA  
3150 C  C   . SER A 228 ? 0.27010 0.65596 0.54521 -0.02644 0.08000  0.08279  208 SER A C   
3151 O  O   . SER A 228 ? 0.26944 0.65676 0.56124 -0.03831 0.06927  0.08689  208 SER A O   
3152 C  CB  . SER A 228 ? 0.22943 0.58370 0.46871 -0.01534 0.07046  0.07073  208 SER A CB  
3153 O  OG  . SER A 228 ? 0.26367 0.60794 0.48207 -0.01737 0.08023  0.07302  208 SER A OG  
3159 N  N   . GLU A 229 ? 0.24716 0.63613 0.51306 -0.02480 0.09408  0.08570  209 GLU A N   
3160 C  CA  . GLU A 229 ? 0.27531 0.67141 0.55161 -0.03689 0.09859  0.09489  209 GLU A CA  
3161 C  C   . GLU A 229 ? 0.36903 0.75267 0.61892 -0.03704 0.10970  0.09737  209 GLU A C   
3162 O  O   . GLU A 229 ? 0.35702 0.73707 0.58772 -0.02501 0.11871  0.09197  209 GLU A O   
3163 C  CB  . GLU A 229 ? 0.33312 0.75551 0.63523 -0.03457 0.10513  0.09744  209 GLU A CB  
3164 C  CG  . GLU A 229 ? 0.41447 0.84579 0.73434 -0.04915 0.10564  0.10720  209 GLU A CG  
3165 C  CD  . GLU A 229 ? 0.52272 0.98130 0.86658 -0.04630 0.11459  0.10995  209 GLU A CD  
3166 O  OE1 . GLU A 229 ? 0.53082 1.00391 0.89495 -0.04036 0.10925  0.10575  209 GLU A OE1 
3167 O  OE2 . GLU A 229 ? 0.62578 1.09123 0.96800 -0.04978 0.12679  0.11636  209 GLU A OE2 
3174 N  N   . VAL A 230 ? 0.34337 0.71832 0.59118 -0.05049 0.10775  0.10510  210 VAL A N   
3175 C  CA  . VAL A 230 ? 0.33472 0.69588 0.55745 -0.05226 0.11606  0.10859  210 VAL A CA  
3176 C  C   . VAL A 230 ? 0.50959 0.87672 0.74556 -0.06575 0.11832  0.11952  210 VAL A C   
3177 O  O   . VAL A 230 ? 0.48082 0.83964 0.72573 -0.07819 0.10764  0.12397  210 VAL A O   
3178 C  CB  . VAL A 230 ? 0.41668 0.75233 0.61597 -0.05430 0.10852  0.10588  210 VAL A CB  
3179 C  CG1 . VAL A 230 ? 0.52901 0.85094 0.70376 -0.05649 0.11610  0.11014  210 VAL A CG1 
3180 C  CG2 . VAL A 230 ? 0.39408 0.72363 0.58023 -0.04131 0.10650  0.09531  210 VAL A CG2 
3190 N  N   . ASP A 231 ? 0.50871 0.88949 0.74573 -0.06327 0.13195  0.12365  211 ASP A N   
3191 C  CA  . ASP A 231 ? 0.53303 0.91909 0.77973 -0.07557 0.13614  0.13476  211 ASP A CA  
3192 C  C   . ASP A 231 ? 0.54229 0.94107 0.82249 -0.08645 0.12671  0.13904  211 ASP A C   
3193 O  O   . ASP A 231 ? 0.63489 1.02505 0.92150 -0.10004 0.11960  0.14596  211 ASP A O   
3194 C  CB  . ASP A 231 ? 0.69258 1.05417 0.91659 -0.08347 0.13332  0.13947  211 ASP A CB  
3195 C  CG  . ASP A 231 ? 0.78750 1.13565 0.97769 -0.07323 0.14144  0.13517  211 ASP A CG  
3196 O  OD1 . ASP A 231 ? 0.85052 1.21016 1.03457 -0.06249 0.15324  0.13187  211 ASP A OD1 
3197 O  OD2 . ASP A 231 ? 0.67159 0.99708 0.84126 -0.07559 0.13525  0.13441  211 ASP A OD2 
3202 N  N   . GLY A 232 ? 0.42103 0.83931 0.72233 -0.08002 0.12576  0.13440  212 GLY A N   
3203 C  CA  . GLY A 232 ? 0.49987 0.93151 0.83345 -0.08896 0.11588  0.13712  212 GLY A CA  
3204 C  C   . GLY A 232 ? 0.42517 0.84010 0.76139 -0.09615 0.09737  0.13417  212 GLY A C   
3205 O  O   . GLY A 232 ? 0.43587 0.85747 0.79634 -0.10552 0.08704  0.13657  212 GLY A O   
3209 N  N   . GLU A 233 ? 0.34939 0.74263 0.66114 -0.09202 0.09256  0.12866  213 GLU A N   
3210 C  CA  . GLU A 233 ? 0.38508 0.76034 0.69575 -0.09839 0.07561  0.12549  213 GLU A CA  
3211 C  C   . GLU A 233 ? 0.34209 0.71825 0.65023 -0.08673 0.06998  0.11554  213 GLU A C   
3212 O  O   . GLU A 233 ? 0.27336 0.65143 0.56646 -0.07385 0.07931  0.11072  213 GLU A O   
3213 C  CB  . GLU A 233 ? 0.38685 0.73534 0.67150 -0.10356 0.07374  0.12740  213 GLU A CB  
3214 C  CG  . GLU A 233 ? 0.45743 0.80133 0.74206 -0.11505 0.07805  0.13763  213 GLU A CG  
3215 C  CD  . GLU A 233 ? 0.63764 0.98052 0.94481 -0.12887 0.06553  0.14185  213 GLU A CD  
3216 O  OE1 . GLU A 233 ? 0.65741 1.00234 0.97836 -0.12913 0.05314  0.13620  213 GLU A OE1 
3217 O  OE2 . GLU A 233 ? 0.70794 1.04828 1.01917 -0.13915 0.06790  0.15069  213 GLU A OE2 
3224 N  N   . ARG A 234 ? 0.21776 0.59067 0.53896 -0.09114 0.05408  0.11225  214 ARG A N   
3225 C  CA  . ARG A 234 ? 0.24203 0.61328 0.56043 -0.08139 0.04617  0.10340  214 ARG A CA  
3226 C  C   . ARG A 234 ? 0.26505 0.61390 0.57524 -0.08870 0.02995  0.10051  214 ARG A C   
3227 O  O   . ARG A 234 ? 0.29951 0.63506 0.60952 -0.10115 0.02365  0.10474  214 ARG A O   
3228 C  CB  . ARG A 234 ? 0.22596 0.61963 0.57088 -0.07665 0.04221  0.10103  214 ARG A CB  
3229 C  CG  . ARG A 234 ? 0.27795 0.69445 0.63194 -0.06797 0.05809  0.10273  214 ARG A CG  
3230 C  CD  . ARG A 234 ? 0.38407 0.81787 0.75425 -0.05630 0.05525  0.09683  214 ARG A CD  
3231 N  NE  . ARG A 234 ? 0.43132 0.88405 0.80637 -0.04639 0.07127  0.09730  214 ARG A NE  
3232 C  CZ  . ARG A 234 ? 0.43292 0.89973 0.81722 -0.03303 0.07332  0.09188  214 ARG A CZ  
3233 N  NH1 . ARG A 234 ? 0.38175 0.84674 0.77176 -0.02750 0.06024  0.08601  214 ARG A NH1 
3234 N  NH2 . ARG A 234 ? 0.50884 0.99099 0.89585 -0.02459 0.08854  0.09228  214 ARG A NH2 
3248 N  N   . LEU A 235 ? 0.22721 0.57010 0.52825 -0.08024 0.02360  0.09305  215 LEU A N   
3249 C  CA  . LEU A 235 ? 0.16856 0.49053 0.46130 -0.08584 0.00761  0.08908  215 LEU A CA  
3250 C  C   . LEU A 235 ? 0.21193 0.53789 0.52582 -0.09194 -0.00828 0.08769  215 LEU A C   
3251 O  O   . LEU A 235 ? 0.22846 0.57251 0.55883 -0.08541 -0.00973 0.08564  215 LEU A O   
3252 C  CB  . LEU A 235 ? 0.19981 0.50233 0.46505 -0.07161 0.00625  0.07777  215 LEU A CB  
3253 C  CG  . LEU A 235 ? 0.20551 0.49547 0.44392 -0.06489 0.01894  0.07614  215 LEU A CG  
3254 C  CD1 . LEU A 235 ? 0.22713 0.50483 0.44510 -0.04997 0.01907  0.06589  215 LEU A CD1 
3255 C  CD2 . LEU A 235 ? 0.24269 0.50732 0.46272 -0.07385 0.01581  0.07754  215 LEU A CD2 
3267 N  N   . SER A 236 ? 0.25318 0.56011 0.56464 -0.10355 -0.02083 0.08789  216 SER A N   
3268 C  CA  . SER A 236 ? 0.24386 0.54814 0.56887 -0.10861 -0.03830 0.08432  216 SER A CA  
3269 C  C   . SER A 236 ? 0.25801 0.55105 0.57057 -0.10055 -0.05054 0.07518  216 SER A C   
3270 O  O   . SER A 236 ? 0.23280 0.50833 0.51720 -0.09051 -0.04493 0.06910  216 SER A O   
3271 C  CB  . SER A 236 ? 0.24132 0.52499 0.56389 -0.12238 -0.04777 0.08627  216 SER A CB  
3272 O  OG  . SER A 236 ? 0.27525 0.53268 0.57312 -0.12257 -0.05283 0.08206  216 SER A OG  
3278 N  N   . ASP A 237 ? 0.29122 0.58471 0.61495 -0.10208 -0.06635 0.07108  217 ASP A N   
3279 C  CA  . ASP A 237 ? 0.24520 0.52254 0.55059 -0.09285 -0.07789 0.06129  217 ASP A CA  
3280 C  C   . ASP A 237 ? 0.26749 0.50863 0.53987 -0.09366 -0.08265 0.05486  217 ASP A C   
3281 O  O   . ASP A 237 ? 0.27432 0.49812 0.51987 -0.08254 -0.08135 0.04746  217 ASP A O   
3282 C  CB  . ASP A 237 ? 0.28939 0.57350 0.61273 -0.09588 -0.09533 0.05882  217 ASP A CB  
3283 C  CG  . ASP A 237 ? 0.36790 0.68147 0.71462 -0.08840 -0.09107 0.06066  217 ASP A CG  
3284 O  OD1 . ASP A 237 ? 0.32766 0.65953 0.68052 -0.08153 -0.07508 0.06463  217 ASP A OD1 
3285 O  OD2 . ASP A 237 ? 0.35542 0.67362 0.71450 -0.08951 -0.10386 0.05786  217 ASP A OD2 
3290 N  N   . ASP A 238 ? 0.31313 0.54218 0.58754 -0.10665 -0.08821 0.05779  218 ASP A N   
3291 C  CA  . ASP A 238 ? 0.32127 0.51700 0.56563 -0.10673 -0.09133 0.05205  218 ASP A CA  
3292 C  C   . ASP A 238 ? 0.26431 0.45287 0.48667 -0.09817 -0.07488 0.05176  218 ASP A C   
3293 O  O   . ASP A 238 ? 0.26443 0.43102 0.45945 -0.09021 -0.07528 0.04431  218 ASP A O   
3294 C  CB  . ASP A 238 ? 0.34984 0.53497 0.60198 -0.12194 -0.09792 0.05668  218 ASP A CB  
3295 C  CG  . ASP A 238 ? 0.45947 0.64069 0.72400 -0.12918 -0.11558 0.05383  218 ASP A CG  
3296 O  OD1 . ASP A 238 ? 0.39755 0.58138 0.66201 -0.12309 -0.12567 0.04753  218 ASP A OD1 
3297 O  OD2 . ASP A 238 ? 0.44477 0.61690 0.71458 -0.13917 -0.11801 0.05721  218 ASP A OD2 
3302 N  N   . GLU A 239 ? 0.24959 0.45681 0.48365 -0.09992 -0.06031 0.06003  219 GLU A N   
3303 C  CA  . GLU A 239 ? 0.23823 0.43897 0.45182 -0.09239 -0.04561 0.05985  219 GLU A CA  
3304 C  C   . GLU A 239 ? 0.21165 0.41437 0.41283 -0.07753 -0.04088 0.05329  219 GLU A C   
3305 O  O   . GLU A 239 ? 0.23710 0.42279 0.41378 -0.07022 -0.03593 0.04852  219 GLU A O   
3306 C  CB  . GLU A 239 ? 0.26127 0.48212 0.48947 -0.09758 -0.03161 0.07036  219 GLU A CB  
3307 C  CG  . GLU A 239 ? 0.27821 0.49098 0.51211 -0.11195 -0.03448 0.07763  219 GLU A CG  
3308 C  CD  . GLU A 239 ? 0.33187 0.56904 0.58671 -0.11952 -0.02262 0.09007  219 GLU A CD  
3309 O  OE1 . GLU A 239 ? 0.31766 0.58212 0.58735 -0.11416 -0.01263 0.09318  219 GLU A OE1 
3310 O  OE2 . GLU A 239 ? 0.44816 0.67592 0.70343 -0.13038 -0.02300 0.09681  219 GLU A OE2 
3317 N  N   . LEU A 240 ? 0.20531 0.42901 0.42446 -0.07301 -0.04258 0.05340  220 LEU A N   
3318 C  CA  . LEU A 240 ? 0.21250 0.43689 0.42076 -0.05881 -0.03930 0.04755  220 LEU A CA  
3319 C  C   . LEU A 240 ? 0.22659 0.42423 0.41015 -0.05402 -0.04920 0.03901  220 LEU A C   
3320 O  O   . LEU A 240 ? 0.21366 0.39930 0.37636 -0.04451 -0.04357 0.03450  220 LEU A O   
3321 C  CB  . LEU A 240 ? 0.21993 0.47063 0.45343 -0.05492 -0.04181 0.04926  220 LEU A CB  
3322 C  CG  . LEU A 240 ? 0.28882 0.56965 0.54521 -0.05430 -0.02845 0.05660  220 LEU A CG  
3323 C  CD1 . LEU A 240 ? 0.34278 0.65124 0.63093 -0.05426 -0.03423 0.05953  220 LEU A CD1 
3324 C  CD2 . LEU A 240 ? 0.26675 0.54460 0.50449 -0.04134 -0.01420 0.05351  220 LEU A CD2 
3336 N  N   . VAL A 241 ? 0.25679 0.44417 0.44178 -0.06070 -0.06400 0.03671  221 VAL A N   
3337 C  CA  . VAL A 241 ? 0.25065 0.41232 0.40998 -0.05567 -0.07244 0.02862  221 VAL A CA  
3338 C  C   . VAL A 241 ? 0.28261 0.42301 0.41790 -0.05459 -0.06501 0.02649  221 VAL A C   
3339 O  O   . VAL A 241 ? 0.23331 0.36051 0.34763 -0.04564 -0.06193 0.02160  221 VAL A O   
3340 C  CB  . VAL A 241 ? 0.26774 0.42105 0.43130 -0.06298 -0.09002 0.02589  221 VAL A CB  
3341 C  CG1 . VAL A 241 ? 0.29754 0.42258 0.43086 -0.05735 -0.09703 0.01740  221 VAL A CG1 
3342 C  CG2 . VAL A 241 ? 0.27972 0.45382 0.46568 -0.06221 -0.09862 0.02717  221 VAL A CG2 
3352 N  N   . MET A 242 ? 0.26079 0.39777 0.39961 -0.06383 -0.06225 0.03069  222 MET A N   
3353 C  CA  . MET A 242 ? 0.26883 0.38534 0.38644 -0.06315 -0.05726 0.02873  222 MET A CA  
3354 C  C   . MET A 242 ? 0.23743 0.35807 0.34587 -0.05519 -0.04295 0.02952  222 MET A C   
3355 O  O   . MET A 242 ? 0.25863 0.36327 0.34668 -0.04916 -0.04019 0.02500  222 MET A O   
3356 C  CB  . MET A 242 ? 0.31089 0.42335 0.43603 -0.07487 -0.05853 0.03402  222 MET A CB  
3357 C  CG  . MET A 242 ? 0.40648 0.50366 0.53160 -0.08175 -0.07405 0.03058  222 MET A CG  
3358 S  SD  . MET A 242 ? 0.56492 0.63011 0.65775 -0.07457 -0.07790 0.02091  222 MET A SD  
3359 C  CE  . MET A 242 ? 0.58246 0.63341 0.67705 -0.08120 -0.09715 0.01590  222 MET A CE  
3369 N  N   . GLU A 243 ? 0.22160 0.36371 0.34499 -0.05489 -0.03386 0.03501  223 GLU A N   
3370 C  CA  . GLU A 243 ? 0.22618 0.37024 0.33920 -0.04737 -0.02110 0.03498  223 GLU A CA  
3371 C  C   . GLU A 243 ? 0.23034 0.37134 0.33316 -0.03583 -0.02081 0.02902  223 GLU A C   
3372 O  O   . GLU A 243 ? 0.23605 0.36620 0.32193 -0.02974 -0.01480 0.02603  223 GLU A O   
3373 C  CB  . GLU A 243 ? 0.24659 0.41370 0.37606 -0.04922 -0.01075 0.04203  223 GLU A CB  
3374 C  CG  . GLU A 243 ? 0.23919 0.40873 0.37665 -0.06063 -0.00880 0.04955  223 GLU A CG  
3375 C  CD  . GLU A 243 ? 0.26620 0.41464 0.38314 -0.06228 -0.00646 0.04902  223 GLU A CD  
3376 O  OE1 . GLU A 243 ? 0.29288 0.43039 0.39148 -0.05407 -0.00254 0.04390  223 GLU A OE1 
3377 O  OE2 . GLU A 243 ? 0.28774 0.43030 0.40830 -0.07216 -0.00959 0.05395  223 GLU A OE2 
3384 N  N   . THR A 244 ? 0.20896 0.35875 0.32212 -0.03291 -0.02799 0.02757  224 THR A N   
3385 C  CA  . THR A 244 ? 0.20257 0.34695 0.30445 -0.02203 -0.02816 0.02272  224 THR A CA  
3386 C  C   . THR A 244 ? 0.24645 0.36647 0.32604 -0.02036 -0.03379 0.01747  224 THR A C   
3387 O  O   . THR A 244 ? 0.24136 0.35198 0.30629 -0.01251 -0.03038 0.01434  224 THR A O   
3388 C  CB  . THR A 244 ? 0.23410 0.39301 0.35092 -0.01784 -0.03484 0.02264  224 THR A CB  
3389 O  OG1 . THR A 244 ? 0.25235 0.41005 0.37663 -0.02428 -0.04824 0.02227  224 THR A OG1 
3390 C  CG2 . THR A 244 ? 0.24284 0.42793 0.38189 -0.01653 -0.02725 0.02736  224 THR A CG2 
3398 N  N   . LEU A 245 ? 0.24218 0.35131 0.31876 -0.02749 -0.04194 0.01651  225 LEU A N   
3399 C  CA  . LEU A 245 ? 0.25538 0.34197 0.30999 -0.02504 -0.04552 0.01139  225 LEU A CA  
3400 C  C   . LEU A 245 ? 0.24988 0.32624 0.29118 -0.02355 -0.03580 0.01109  225 LEU A C   
3401 O  O   . LEU A 245 ? 0.24823 0.31218 0.27312 -0.01745 -0.03355 0.00768  225 LEU A O   
3402 C  CB  . LEU A 245 ? 0.27957 0.35621 0.33387 -0.03232 -0.05670 0.00967  225 LEU A CB  
3403 C  CG  . LEU A 245 ? 0.28952 0.34353 0.32085 -0.02881 -0.06058 0.00377  225 LEU A CG  
3404 C  CD1 . LEU A 245 ? 0.31835 0.36880 0.33733 -0.01935 -0.06191 0.00060  225 LEU A CD1 
3405 C  CD2 . LEU A 245 ? 0.36225 0.40656 0.39415 -0.03553 -0.07308 0.00122  225 LEU A CD2 
3417 N  N   . LEU A 246 ? 0.24827 0.32975 0.29662 -0.02937 -0.03031 0.01514  226 LEU A N   
3418 C  CA  . LEU A 246 ? 0.23020 0.30419 0.26761 -0.02790 -0.02174 0.01534  226 LEU A CA  
3419 C  C   . LEU A 246 ? 0.22641 0.30380 0.25834 -0.01940 -0.01434 0.01392  226 LEU A C   
3420 O  O   . LEU A 246 ? 0.24072 0.30632 0.25891 -0.01547 -0.01121 0.01124  226 LEU A O   
3421 C  CB  . LEU A 246 ? 0.22440 0.30630 0.27137 -0.03518 -0.01723 0.02114  226 LEU A CB  
3422 C  CG  . LEU A 246 ? 0.22861 0.30374 0.26471 -0.03408 -0.00942 0.02194  226 LEU A CG  
3423 C  CD1 . LEU A 246 ? 0.26810 0.32359 0.28977 -0.03352 -0.01274 0.01824  226 LEU A CD1 
3424 C  CD2 . LEU A 246 ? 0.25316 0.33715 0.29830 -0.04133 -0.00530 0.02887  226 LEU A CD2 
3436 N  N   . ILE A 247 ? 0.23562 0.32894 0.27911 -0.01633 -0.01195 0.01559  227 ILE A N   
3437 C  CA  . ILE A 247 ? 0.22563 0.32100 0.26439 -0.00772 -0.00581 0.01383  227 ILE A CA  
3438 C  C   . ILE A 247 ? 0.23243 0.31558 0.25964 -0.00165 -0.01027 0.00993  227 ILE A C   
3439 O  O   . ILE A 247 ? 0.27788 0.35280 0.29441 0.00365  -0.00590 0.00798  227 ILE A O   
3440 C  CB  . ILE A 247 ? 0.26684 0.38297 0.32240 -0.00531 -0.00282 0.01645  227 ILE A CB  
3441 C  CG1 . ILE A 247 ? 0.24508 0.37270 0.30780 -0.00946 0.00532  0.02070  227 ILE A CG1 
3442 C  CG2 . ILE A 247 ? 0.23973 0.35709 0.29219 0.00499  0.00007  0.01376  227 ILE A CG2 
3443 C  CD1 . ILE A 247 ? 0.25085 0.40211 0.33482 -0.01000 0.00731  0.02477  227 ILE A CD1 
3455 N  N   . LEU A 248 ? 0.24737 0.32953 0.27665 -0.00228 -0.01915 0.00911  228 LEU A N   
3456 C  CA  . LEU A 248 ? 0.24598 0.31655 0.26248 0.00370  -0.02323 0.00628  228 LEU A CA  
3457 C  C   . LEU A 248 ? 0.25437 0.30755 0.25366 0.00374  -0.02050 0.00415  228 LEU A C   
3458 O  O   . LEU A 248 ? 0.24513 0.29030 0.23411 0.00911  -0.01694 0.00322  228 LEU A O   
3459 C  CB  . LEU A 248 ? 0.26287 0.33371 0.28197 0.00225  -0.03436 0.00546  228 LEU A CB  
3460 C  CG  . LEU A 248 ? 0.28004 0.33623 0.28169 0.00760  -0.03928 0.00279  228 LEU A CG  
3461 C  CD1 . LEU A 248 ? 0.28287 0.34203 0.28396 0.01567  -0.03733 0.00377  228 LEU A CD1 
3462 C  CD2 . LEU A 248 ? 0.29966 0.35330 0.30052 0.00512  -0.05140 0.00103  228 LEU A CD2 
3474 N  N   . ILE A 249 ? 0.24808 0.29549 0.24529 -0.00227 -0.02205 0.00371  229 ILE A N   
3475 C  CA  . ILE A 249 ? 0.25525 0.28762 0.23796 -0.00171 -0.01965 0.00159  229 ILE A CA  
3476 C  C   . ILE A 249 ? 0.26980 0.30156 0.25059 -0.00056 -0.01082 0.00245  229 ILE A C   
3477 O  O   . ILE A 249 ? 0.28320 0.30570 0.25388 0.00271  -0.00752 0.00121  229 ILE A O   
3478 C  CB  . ILE A 249 ? 0.28383 0.30955 0.26546 -0.00752 -0.02464 0.00046  229 ILE A CB  
3479 C  CG1 . ILE A 249 ? 0.30269 0.32657 0.28423 -0.00847 -0.03482 -0.00147 229 ILE A CG1 
3480 C  CG2 . ILE A 249 ? 0.29264 0.30415 0.26052 -0.00571 -0.02171 -0.00195 229 ILE A CG2 
3481 C  CD1 . ILE A 249 ? 0.40131 0.41951 0.38516 -0.01512 -0.04128 -0.00254 229 ILE A CD1 
3493 N  N   . GLY A 250 ? 0.23519 0.27668 0.22529 -0.00340 -0.00697 0.00473  230 GLY A N   
3494 C  CA  . GLY A 250 ? 0.24643 0.28748 0.23352 -0.00120 0.00021  0.00486  230 GLY A CA  
3495 C  C   . GLY A 250 ? 0.28052 0.32021 0.26398 0.00557  0.00229  0.00358  230 GLY A C   
3496 O  O   . GLY A 250 ? 0.28426 0.31545 0.25996 0.00788  0.00556  0.00242  230 GLY A O   
3500 N  N   . GLY A 251 ? 0.24963 0.29710 0.23937 0.00870  -0.00031 0.00403  231 GLY A N   
3501 C  CA  . GLY A 251 ? 0.28337 0.32864 0.27005 0.01565  0.00114  0.00322  231 GLY A CA  
3502 C  C   . GLY A 251 ? 0.30286 0.33413 0.27733 0.01807  -0.00058 0.00251  231 GLY A C   
3503 O  O   . GLY A 251 ? 0.34734 0.37169 0.31636 0.02189  0.00246  0.00226  231 GLY A O   
3507 N  N   . ASP A 252 ? 0.25969 0.28598 0.22912 0.01589  -0.00529 0.00228  232 ASP A N   
3508 C  CA  . ASP A 252 ? 0.23707 0.25192 0.19423 0.01938  -0.00647 0.00231  232 ASP A CA  
3509 C  C   . ASP A 252 ? 0.29580 0.30081 0.24342 0.01694  -0.00470 0.00144  232 ASP A C   
3510 O  O   . ASP A 252 ? 0.28169 0.27795 0.21843 0.01982  -0.00448 0.00197  232 ASP A O   
3511 C  CB  . ASP A 252 ? 0.26066 0.27682 0.21632 0.02222  -0.01399 0.00262  232 ASP A CB  
3512 C  CG  . ASP A 252 ? 0.28880 0.30653 0.24547 0.01800  -0.02076 0.00106  232 ASP A CG  
3513 O  OD1 . ASP A 252 ? 0.26336 0.27819 0.21919 0.01338  -0.01945 -0.00019 232 ASP A OD1 
3514 O  OD2 . ASP A 252 ? 0.29893 0.31958 0.25671 0.01956  -0.02857 0.00092  232 ASP A OD2 
3519 N  N   . GLU A 253 ? 0.26882 0.27504 0.21999 0.01234  -0.00283 0.00055  233 GLU A N   
3520 C  CA  . GLU A 253 ? 0.28468 0.28222 0.22817 0.01114  -0.00084 -0.00048 233 GLU A CA  
3521 C  C   . GLU A 253 ? 0.28814 0.28504 0.23447 0.00917  0.00468  -0.00016 233 GLU A C   
3522 O  O   . GLU A 253 ? 0.30923 0.30064 0.25160 0.00853  0.00649  -0.00086 233 GLU A O   
3523 C  CB  . GLU A 253 ? 0.30411 0.30027 0.24723 0.00795  -0.00596 -0.00240 233 GLU A CB  
3524 C  CG  . GLU A 253 ? 0.31684 0.31068 0.25434 0.00977  -0.01296 -0.00374 233 GLU A CG  
3525 C  CD  . GLU A 253 ? 0.38296 0.36748 0.30564 0.01489  -0.01178 -0.00414 233 GLU A CD  
3526 O  OE1 . GLU A 253 ? 0.37728 0.35644 0.29431 0.01621  -0.00541 -0.00376 233 GLU A OE1 
3527 O  OE2 . GLU A 253 ? 0.37734 0.36022 0.29389 0.01758  -0.01746 -0.00455 233 GLU A OE2 
3534 N  N   . THR A 254 ? 0.25227 0.25464 0.20501 0.00870  0.00707  0.00054  234 THR A N   
3535 C  CA  . THR A 254 ? 0.27171 0.27343 0.22650 0.00665  0.01071  0.00045  234 THR A CA  
3536 C  C   . THR A 254 ? 0.25974 0.25817 0.21330 0.00914  0.01395  0.00065  234 THR A C   
3537 O  O   . THR A 254 ? 0.25455 0.24743 0.20613 0.00861  0.01621  0.00095  234 THR A O   
3538 C  CB  . THR A 254 ? 0.27167 0.28109 0.23282 0.00362  0.01050  0.00080  234 THR A CB  
3539 O  OG1 . THR A 254 ? 0.26453 0.28121 0.22972 0.00604  0.01108  0.00107  234 THR A OG1 
3540 C  CG2 . THR A 254 ? 0.27373 0.28468 0.23717 -0.00016 0.00682  0.00128  234 THR A CG2 
3548 N  N   . THR A 255 ? 0.24280 0.24461 0.19858 0.01182  0.01410  0.00045  235 THR A N   
3549 C  CA  . THR A 255 ? 0.24785 0.24490 0.20255 0.01406  0.01626  -0.00010 235 THR A CA  
3550 C  C   . THR A 255 ? 0.25173 0.23974 0.20189 0.01506  0.01715  0.00160  235 THR A C   
3551 O  O   . THR A 255 ? 0.26597 0.24820 0.21618 0.01422  0.01886  0.00166  235 THR A O   
3552 C  CB  . THR A 255 ? 0.24629 0.24790 0.20349 0.01845  0.01581  -0.00088 235 THR A CB  
3553 O  OG1 . THR A 255 ? 0.26515 0.27736 0.22749 0.01710  0.01608  -0.00143 235 THR A OG1 
3554 C  CG2 . THR A 255 ? 0.31457 0.30949 0.26994 0.02147  0.01727  -0.00246 235 THR A CG2 
3562 N  N   . ARG A 256 ? 0.24430 0.23083 0.19022 0.01670  0.01577  0.00327  236 ARG A N   
3563 C  CA  . ARG A 256 ? 0.24190 0.22026 0.18171 0.01779  0.01753  0.00600  236 ARG A CA  
3564 C  C   . ARG A 256 ? 0.26687 0.24242 0.20811 0.01431  0.02121  0.00668  236 ARG A C   
3565 O  O   . ARG A 256 ? 0.26332 0.23297 0.20376 0.01400  0.02384  0.00930  236 ARG A O   
3566 C  CB  . ARG A 256 ? 0.27020 0.24802 0.20283 0.01970  0.01531  0.00699  236 ARG A CB  
3567 C  CG  . ARG A 256 ? 0.27232 0.25326 0.20456 0.01722  0.01434  0.00493  236 ARG A CG  
3568 C  CD  . ARG A 256 ? 0.30502 0.28570 0.23071 0.01913  0.00974  0.00422  236 ARG A CD  
3569 N  NE  . ARG A 256 ? 0.33390 0.30714 0.24772 0.02227  0.01118  0.00627  236 ARG A NE  
3570 C  CZ  . ARG A 256 ? 0.37570 0.34631 0.27995 0.02498  0.00669  0.00565  236 ARG A CZ  
3571 N  NH1 . ARG A 256 ? 0.35922 0.33440 0.26665 0.02452  -0.00031 0.00325  236 ARG A NH1 
3572 N  NH2 . ARG A 256 ? 0.40126 0.36466 0.29233 0.02805  0.00913  0.00766  236 ARG A NH2 
3586 N  N   . HIS A 257 ? 0.24379 0.22362 0.18798 0.01164  0.02119  0.00489  237 HIS A N   
3587 C  CA  . HIS A 257 ? 0.23780 0.21662 0.18496 0.00911  0.02419  0.00554  237 HIS A CA  
3588 C  C   . HIS A 257 ? 0.23832 0.21664 0.19203 0.00656  0.02434  0.00493  237 HIS A C   
3589 O  O   . HIS A 257 ? 0.25699 0.23377 0.21482 0.00452  0.02663  0.00652  237 HIS A O   
3590 C  CB  . HIS A 257 ? 0.24700 0.22929 0.19477 0.00803  0.02317  0.00371  237 HIS A CB  
3591 C  CG  . HIS A 257 ? 0.25259 0.23341 0.19279 0.01047  0.02206  0.00333  237 HIS A CG  
3592 N  ND1 . HIS A 257 ? 0.27814 0.25476 0.21084 0.01322  0.02487  0.00526  237 HIS A ND1 
3593 C  CD2 . HIS A 257 ? 0.28457 0.26689 0.22279 0.01045  0.01789  0.00125  237 HIS A CD2 
3594 C  CE1 . HIS A 257 ? 0.29933 0.27430 0.22412 0.01545  0.02200  0.00364  237 HIS A CE1 
3595 N  NE2 . HIS A 257 ? 0.30186 0.28007 0.23080 0.01345  0.01733  0.00103  237 HIS A NE2 
3603 N  N   . THR A 258 ? 0.24713 0.22693 0.20184 0.00688  0.02192  0.00265  238 THR A N   
3604 C  CA  . THR A 258 ? 0.22564 0.20262 0.18371 0.00528  0.02118  0.00126  238 THR A CA  
3605 C  C   . THR A 258 ? 0.26401 0.23314 0.22109 0.00655  0.02165  0.00264  238 THR A C   
3606 O  O   . THR A 258 ? 0.26771 0.23200 0.22864 0.00391  0.02148  0.00312  238 THR A O   
3607 C  CB  . THR A 258 ? 0.23999 0.22075 0.19721 0.00597  0.01919  -0.00188 238 THR A CB  
3608 O  OG1 . THR A 258 ? 0.25458 0.24117 0.21290 0.00388  0.01859  -0.00197 238 THR A OG1 
3609 C  CG2 . THR A 258 ? 0.27579 0.25185 0.23367 0.00497  0.01757  -0.00431 238 THR A CG2 
3617 N  N   . LEU A 259 ? 0.24337 0.21061 0.19596 0.01033  0.02164  0.00377  239 LEU A N   
3618 C  CA  . LEU A 259 ? 0.27406 0.23199 0.22497 0.01179  0.02180  0.00606  239 LEU A CA  
3619 C  C   . LEU A 259 ? 0.30434 0.25826 0.25683 0.00845  0.02490  0.01074  239 LEU A C   
3620 O  O   . LEU A 259 ? 0.29752 0.24429 0.25357 0.00595  0.02487  0.01230  239 LEU A O   
3621 C  CB  . LEU A 259 ? 0.30903 0.26647 0.25458 0.01697  0.02075  0.00725  239 LEU A CB  
3622 C  CG  . LEU A 259 ? 0.34841 0.30696 0.29437 0.02144  0.01830  0.00372  239 LEU A CG  
3623 C  CD1 . LEU A 259 ? 0.35581 0.31606 0.29863 0.02662  0.01656  0.00548  239 LEU A CD1 
3624 C  CD2 . LEU A 259 ? 0.35436 0.30235 0.30069 0.02236  0.01721  0.00218  239 LEU A CD2 
3636 N  N   . SER A 260 ? 0.28618 0.24458 0.23625 0.00840  0.02766  0.01299  240 SER A N   
3637 C  CA  . SER A 260 ? 0.27521 0.23155 0.22615 0.00621  0.03226  0.01801  240 SER A CA  
3638 C  C   . SER A 260 ? 0.27809 0.23823 0.23967 0.00139  0.03343  0.01761  240 SER A C   
3639 O  O   . SER A 260 ? 0.28258 0.23907 0.25052 -0.00218 0.03496  0.02096  240 SER A O   
3640 C  CB  . SER A 260 ? 0.28387 0.24327 0.22675 0.00899  0.03501  0.01967  240 SER A CB  
3641 O  OG  . SER A 260 ? 0.27940 0.24592 0.22415 0.00881  0.03402  0.01572  240 SER A OG  
3647 N  N   . GLY A 261 ? 0.26559 0.23286 0.23011 0.00096  0.03210  0.01393  241 GLY A N   
3648 C  CA  . GLY A 261 ? 0.25140 0.22314 0.22638 -0.00286 0.03251  0.01379  241 GLY A CA  
3649 C  C   . GLY A 261 ? 0.27248 0.24051 0.25379 -0.00622 0.02813  0.01182  241 GLY A C   
3650 O  O   . GLY A 261 ? 0.26455 0.23394 0.25625 -0.01038 0.02804  0.01336  241 GLY A O   
3654 N  N   . GLY A 262 ? 0.26637 0.23005 0.24188 -0.00425 0.02425  0.00818  242 GLY A N   
3655 C  CA  . GLY A 262 ? 0.26808 0.22600 0.24638 -0.00634 0.01964  0.00519  242 GLY A CA  
3656 C  C   . GLY A 262 ? 0.29579 0.24437 0.27739 -0.00868 0.01980  0.00843  242 GLY A C   
3657 O  O   . GLY A 262 ? 0.27753 0.22294 0.26736 -0.01334 0.01696  0.00839  242 GLY A O   
3661 N  N   . THR A 263 ? 0.29111 0.23472 0.26665 -0.00579 0.02243  0.01165  243 THR A N   
3662 C  CA  . THR A 263 ? 0.28634 0.21973 0.26442 -0.00826 0.02284  0.01613  243 THR A CA  
3663 C  C   . THR A 263 ? 0.31675 0.25446 0.30537 -0.01400 0.02690  0.02197  243 THR A C   
3664 O  O   . THR A 263 ? 0.29159 0.22334 0.28886 -0.01929 0.02528  0.02443  243 THR A O   
3665 C  CB  . THR A 263 ? 0.29197 0.21967 0.26037 -0.00342 0.02480  0.01935  243 THR A CB  
3666 O  OG1 . THR A 263 ? 0.32005 0.24621 0.28146 0.00228  0.02124  0.01393  243 THR A OG1 
3667 C  CG2 . THR A 263 ? 0.33793 0.25323 0.30778 -0.00587 0.02495  0.02481  243 THR A CG2 
3675 N  N   . GLU A 264 ? 0.30901 0.25749 0.29809 -0.01306 0.03199  0.02395  244 GLU A N   
3676 C  CA  . GLU A 264 ? 0.29119 0.24664 0.29143 -0.01738 0.03709  0.02926  244 GLU A CA  
3677 C  C   . GLU A 264 ? 0.29075 0.24904 0.30592 -0.02317 0.03254  0.02728  244 GLU A C   
3678 O  O   . GLU A 264 ? 0.31086 0.26971 0.33852 -0.02887 0.03411  0.03227  244 GLU A O   
3679 C  CB  . GLU A 264 ? 0.30812 0.27443 0.30551 -0.01384 0.04223  0.02931  244 GLU A CB  
3680 C  CG  . GLU A 264 ? 0.31472 0.28942 0.32346 -0.01683 0.04908  0.03505  244 GLU A CG  
3681 C  CD  . GLU A 264 ? 0.36817 0.35397 0.37724 -0.01310 0.05312  0.03342  244 GLU A CD  
3682 O  OE1 . GLU A 264 ? 0.35143 0.33848 0.35479 -0.00976 0.04911  0.02754  244 GLU A OE1 
3683 O  OE2 . GLU A 264 ? 0.41323 0.40648 0.42902 -0.01352 0.06062  0.03834  244 GLU A OE2 
3690 N  N   . GLN A 265 ? 0.27477 0.23512 0.28894 -0.02200 0.02661  0.02044  245 GLN A N   
3691 C  CA  . GLN A 265 ? 0.26642 0.22850 0.29296 -0.02708 0.02077  0.01820  245 GLN A CA  
3692 C  C   . GLN A 265 ? 0.30556 0.25501 0.33485 -0.03129 0.01517  0.01767  245 GLN A C   
3693 O  O   . GLN A 265 ? 0.31426 0.26459 0.35783 -0.03763 0.01181  0.01912  245 GLN A O   
3694 C  CB  . GLN A 265 ? 0.26528 0.23083 0.28700 -0.02443 0.01542  0.01144  245 GLN A CB  
3695 C  CG  . GLN A 265 ? 0.27863 0.25598 0.30201 -0.02186 0.01898  0.01195  245 GLN A CG  
3696 C  CD  . GLN A 265 ? 0.30230 0.28924 0.34232 -0.02527 0.02223  0.01649  245 GLN A CD  
3697 O  OE1 . GLN A 265 ? 0.37900 0.36741 0.43196 -0.03022 0.01758  0.01665  245 GLN A OE1 
3698 N  NE2 . GLN A 265 ? 0.33835 0.33200 0.37829 -0.02241 0.02994  0.01996  245 GLN A NE2 
3707 N  N   . LEU A 266 ? 0.30144 0.23892 0.31840 -0.02784 0.01363  0.01563  246 LEU A N   
3708 C  CA  . LEU A 266 ? 0.30598 0.22877 0.32456 -0.03113 0.00806  0.01486  246 LEU A CA  
3709 C  C   . LEU A 266 ? 0.31764 0.23819 0.34758 -0.03735 0.01198  0.02376  246 LEU A C   
3710 O  O   . LEU A 266 ? 0.35364 0.26682 0.39420 -0.04406 0.00696  0.02481  246 LEU A O   
3711 C  CB  . LEU A 266 ? 0.33544 0.24653 0.33872 -0.02460 0.00665  0.01132  246 LEU A CB  
3712 C  CG  . LEU A 266 ? 0.33033 0.24345 0.32265 -0.01848 0.00353  0.00307  246 LEU A CG  
3713 C  CD1 . LEU A 266 ? 0.37182 0.27581 0.35218 -0.01164 0.00354  0.00086  246 LEU A CD1 
3714 C  CD2 . LEU A 266 ? 0.35914 0.26788 0.35370 -0.02126 -0.00466 -0.00345 246 LEU A CD2 
3726 N  N   . LEU A 267 ? 0.32460 0.25084 0.35176 -0.03534 0.02082  0.03048  247 LEU A N   
3727 C  CA  . LEU A 267 ? 0.33260 0.25720 0.36825 -0.04069 0.02638  0.04034  247 LEU A CA  
3728 C  C   . LEU A 267 ? 0.34649 0.28510 0.40176 -0.04731 0.02941  0.04459  247 LEU A C   
3729 O  O   . LEU A 267 ? 0.41960 0.35603 0.48822 -0.05479 0.03060  0.05155  247 LEU A O   
3730 C  CB  . LEU A 267 ? 0.34930 0.27483 0.37244 -0.03539 0.03479  0.04592  247 LEU A CB  
3731 C  CG  . LEU A 267 ? 0.34975 0.26242 0.35588 -0.02882 0.03180  0.04319  247 LEU A CG  
3732 C  CD1 . LEU A 267 ? 0.37046 0.28594 0.36449 -0.02371 0.03927  0.04875  247 LEU A CD1 
3733 C  CD2 . LEU A 267 ? 0.42099 0.31532 0.42831 -0.03202 0.02641  0.04487  247 LEU A CD2 
3745 N  N   . ARG A 268 ? 0.31799 0.27098 0.37653 -0.04482 0.03043  0.04090  248 ARG A N   
3746 C  CA  . ARG A 268 ? 0.35162 0.31948 0.43007 -0.04974 0.03286  0.04427  248 ARG A CA  
3747 C  C   . ARG A 268 ? 0.37177 0.33764 0.46518 -0.05662 0.02248  0.04079  248 ARG A C   
3748 O  O   . ARG A 268 ? 0.40237 0.37811 0.51683 -0.06324 0.02328  0.04558  248 ARG A O   
3749 C  CB  . ARG A 268 ? 0.35723 0.33913 0.43330 -0.04376 0.03638  0.04107  248 ARG A CB  
3750 C  CG  . ARG A 268 ? 0.40583 0.39091 0.46934 -0.03766 0.04651  0.04473  248 ARG A CG  
3751 C  CD  . ARG A 268 ? 0.49928 0.49947 0.56669 -0.03347 0.05195  0.04409  248 ARG A CD  
3752 N  NE  . ARG A 268 ? 0.59106 0.59180 0.64409 -0.02753 0.06098  0.04707  248 ARG A NE  
3753 C  CZ  . ARG A 268 ? 0.54859 0.55405 0.60427 -0.02813 0.07099  0.05506  248 ARG A CZ  
3754 N  NH1 . ARG A 268 ? 0.53586 0.54749 0.61066 -0.03508 0.07418  0.06182  248 ARG A NH1 
3755 N  NH2 . ARG A 268 ? 0.51210 0.51610 0.55056 -0.02176 0.07787  0.05655  248 ARG A NH2 
3769 N  N   . ASN A 269 ? 0.36824 0.32207 0.45137 -0.05501 0.01275  0.03257  249 ASN A N   
3770 C  CA  . ASN A 269 ? 0.38903 0.33744 0.48151 -0.06061 0.00109  0.02762  249 ASN A CA  
3771 C  C   . ASN A 269 ? 0.36204 0.28944 0.44623 -0.06226 -0.00482 0.02557  249 ASN A C   
3772 O  O   . ASN A 269 ? 0.39644 0.31332 0.46437 -0.05690 -0.01040 0.01748  249 ASN A O   
3773 C  CB  . ASN A 269 ? 0.37556 0.32791 0.45951 -0.05553 -0.00532 0.01853  249 ASN A CB  
3774 C  CG  . ASN A 269 ? 0.45472 0.42544 0.54506 -0.05272 0.00027  0.02043  249 ASN A CG  
3775 O  OD1 . ASN A 269 ? 0.43933 0.42163 0.54917 -0.05733 -0.00078 0.02333  249 ASN A OD1 
3776 N  ND2 . ASN A 269 ? 0.34603 0.31944 0.42105 -0.04507 0.00540  0.01849  249 ASN A ND2 
3783 N  N   . ARG A 270 ? 0.37727 0.29841 0.47248 -0.06930 -0.00322 0.03312  250 ARG A N   
3784 C  CA  . ARG A 270 ? 0.39895 0.29826 0.48433 -0.06954 -0.00746 0.03228  250 ARG A CA  
3785 C  C   . ARG A 270 ? 0.40137 0.28586 0.48392 -0.07105 -0.02122 0.02251  250 ARG A C   
3786 O  O   . ARG A 270 ? 0.40642 0.27224 0.47498 -0.06732 -0.02524 0.01832  250 ARG A O   
3787 C  CB  . ARG A 270 ? 0.52970 0.42408 0.62738 -0.07742 -0.00292 0.04362  250 ARG A CB  
3788 C  CG  . ARG A 270 ? 0.60585 0.50114 0.69131 -0.07189 0.00870  0.05087  250 ARG A CG  
3789 C  CD  . ARG A 270 ? 0.66279 0.54315 0.75036 -0.07717 0.01068  0.06037  250 ARG A CD  
3790 N  NE  . ARG A 270 ? 0.64612 0.50636 0.71421 -0.07060 0.00743  0.05738  250 ARG A NE  
3791 C  CZ  . ARG A 270 ? 0.51138 0.37184 0.56251 -0.06202 0.01416  0.05936  250 ARG A CZ  
3792 N  NH1 . ARG A 270 ? 0.48983 0.36821 0.53802 -0.05815 0.02346  0.06210  250 ARG A NH1 
3793 N  NH2 . ARG A 270 ? 0.55999 0.40173 0.59698 -0.05691 0.01076  0.05830  250 ARG A NH2 
3807 N  N   . ASP A 271 ? 0.39888 0.29081 0.49309 -0.07546 -0.02889 0.01829  251 ASP A N   
3808 C  CA  . ASP A 271 ? 0.42050 0.29834 0.50635 -0.07473 -0.04216 0.00733  251 ASP A CA  
3809 C  C   . ASP A 271 ? 0.40960 0.28279 0.47023 -0.06316 -0.04146 -0.00121 251 ASP A C   
3810 O  O   . ASP A 271 ? 0.42756 0.28333 0.47462 -0.05978 -0.04914 -0.00945 251 ASP A O   
3811 C  CB  . ASP A 271 ? 0.41335 0.30225 0.51380 -0.08007 -0.05052 0.00432  251 ASP A CB  
3812 C  CG  . ASP A 271 ? 0.44988 0.36000 0.54971 -0.07482 -0.04453 0.00447  251 ASP A CG  
3813 O  OD1 . ASP A 271 ? 0.49511 0.41998 0.60287 -0.07435 -0.03309 0.01254  251 ASP A OD1 
3814 O  OD2 . ASP A 271 ? 0.51227 0.42337 0.60230 -0.07073 -0.05133 -0.00355 251 ASP A OD2 
3819 N  N   . GLN A 272 ? 0.37299 0.26133 0.42742 -0.05692 -0.03217 0.00071  252 GLN A N   
3820 C  CA  . GLN A 272 ? 0.35050 0.23720 0.38381 -0.04685 -0.03080 -0.00618 252 GLN A CA  
3821 C  C   . GLN A 272 ? 0.40022 0.27407 0.42126 -0.04146 -0.02692 -0.00550 252 GLN A C   
3822 O  O   . GLN A 272 ? 0.39037 0.25278 0.39639 -0.03508 -0.03074 -0.01304 252 GLN A O   
3823 C  CB  . GLN A 272 ? 0.35773 0.26362 0.39022 -0.04308 -0.02340 -0.00405 252 GLN A CB  
3824 C  CG  . GLN A 272 ? 0.35102 0.26883 0.39417 -0.04673 -0.02808 -0.00532 252 GLN A CG  
3825 C  CD  . GLN A 272 ? 0.39064 0.30179 0.42186 -0.04405 -0.03772 -0.01475 252 GLN A CD  
3826 O  OE1 . GLN A 272 ? 0.39553 0.30854 0.41107 -0.03700 -0.03542 -0.01862 252 GLN A OE1 
3827 N  NE2 . GLN A 272 ? 0.43090 0.33512 0.46965 -0.04987 -0.04859 -0.01815 252 GLN A NE2 
3836 N  N   . TRP A 273 ? 0.37770 0.25340 0.40475 -0.04344 -0.01927 0.00373  253 TRP A N   
3837 C  CA  . TRP A 273 ? 0.39183 0.25366 0.40917 -0.03921 -0.01695 0.00575  253 TRP A CA  
3838 C  C   . TRP A 273 ? 0.40203 0.24145 0.41673 -0.04063 -0.02658 0.00066  253 TRP A C   
3839 O  O   . TRP A 273 ? 0.42698 0.25426 0.42721 -0.03271 -0.02863 -0.00510 253 TRP A O   
3840 C  CB  . TRP A 273 ? 0.39426 0.26023 0.42007 -0.04332 -0.00856 0.01767  253 TRP A CB  
3841 C  CG  . TRP A 273 ? 0.37627 0.22767 0.39311 -0.03980 -0.00636 0.02194  253 TRP A CG  
3842 C  CD1 . TRP A 273 ? 0.42361 0.25673 0.44416 -0.04440 -0.01017 0.02587  253 TRP A CD1 
3843 C  CD2 . TRP A 273 ? 0.37642 0.22998 0.37946 -0.03093 -0.00061 0.02311  253 TRP A CD2 
3844 N  NE1 . TRP A 273 ? 0.42636 0.24971 0.43532 -0.03824 -0.00706 0.02946  253 TRP A NE1 
3845 C  CE2 . TRP A 273 ? 0.39750 0.23380 0.39594 -0.02988 -0.00139 0.02774  253 TRP A CE2 
3846 C  CE3 . TRP A 273 ? 0.36603 0.23394 0.36087 -0.02413 0.00427  0.02083  253 TRP A CE3 
3847 C  CZ2 . TRP A 273 ? 0.42283 0.25684 0.40870 -0.02171 0.00237  0.03017  253 TRP A CZ2 
3848 C  CZ3 . TRP A 273 ? 0.35795 0.22388 0.34122 -0.01677 0.00781  0.02294  253 TRP A CZ3 
3849 C  CH2 . TRP A 273 ? 0.37295 0.22256 0.35186 -0.01536 0.00672  0.02754  253 TRP A CH2 
3860 N  N   . ASP A 274 ? 0.41108 0.24487 0.44042 -0.05047 -0.03290 0.00247  254 ASP A N   
3861 C  CA  . ASP A 274 ? 0.45625 0.26640 0.48419 -0.05303 -0.04325 -0.00220 254 ASP A CA  
3862 C  C   . ASP A 274 ? 0.49133 0.29291 0.50364 -0.04591 -0.05157 -0.01593 254 ASP A C   
3863 O  O   . ASP A 274 ? 0.53189 0.31333 0.53243 -0.04074 -0.05668 -0.02201 254 ASP A O   
3864 C  CB  . ASP A 274 ? 0.48920 0.29727 0.53849 -0.06629 -0.04922 0.00258  254 ASP A CB  
3865 C  CG  . ASP A 274 ? 0.53589 0.34858 0.59966 -0.07345 -0.04067 0.01687  254 ASP A CG  
3866 O  OD1 . ASP A 274 ? 0.53945 0.34887 0.59347 -0.06801 -0.03285 0.02212  254 ASP A OD1 
3867 O  OD2 . ASP A 274 ? 0.53947 0.35877 0.62430 -0.08444 -0.04204 0.02307  254 ASP A OD2 
3872 N  N   . LEU A 275 ? 0.45827 0.27469 0.46895 -0.04461 -0.05246 -0.02075 255 LEU A N   
3873 C  CA  . LEU A 275 ? 0.46257 0.27221 0.45646 -0.03759 -0.05922 -0.03301 255 LEU A CA  
3874 C  C   . LEU A 275 ? 0.46891 0.27509 0.44446 -0.02542 -0.05342 -0.03684 255 LEU A C   
3875 O  O   . LEU A 275 ? 0.52053 0.31085 0.48198 -0.01880 -0.05869 -0.04587 255 LEU A O   
3876 C  CB  . LEU A 275 ? 0.50981 0.33747 0.50459 -0.03812 -0.05973 -0.03529 255 LEU A CB  
3877 C  CG  . LEU A 275 ? 0.64092 0.46776 0.64513 -0.04598 -0.07112 -0.03874 255 LEU A CG  
3878 C  CD1 . LEU A 275 ? 0.56924 0.41660 0.57389 -0.04481 -0.06902 -0.03861 255 LEU A CD1 
3879 C  CD2 . LEU A 275 ? 0.68137 0.48689 0.67132 -0.04341 -0.08327 -0.05041 255 LEU A CD2 
3891 N  N   . LEU A 276 ? 0.45975 0.28118 0.43563 -0.02196 -0.04270 -0.03028 256 LEU A N   
3892 C  CA  . LEU A 276 ? 0.48434 0.30625 0.44567 -0.01075 -0.03726 -0.03331 256 LEU A CA  
3893 C  C   . LEU A 276 ? 0.54286 0.34582 0.50017 -0.00689 -0.03859 -0.03305 256 LEU A C   
3894 O  O   . LEU A 276 ? 0.56532 0.36146 0.50960 0.00315  -0.03866 -0.03966 256 LEU A O   
3895 C  CB  . LEU A 276 ? 0.48296 0.32487 0.44716 -0.00920 -0.02701 -0.02602 256 LEU A CB  
3896 C  CG  . LEU A 276 ? 0.52532 0.38526 0.48784 -0.00850 -0.02449 -0.02781 256 LEU A CG  
3897 C  CD1 . LEU A 276 ? 0.48693 0.36206 0.44961 -0.00519 -0.01504 -0.02171 256 LEU A CD1 
3898 C  CD2 . LEU A 276 ? 0.50321 0.35971 0.45131 -0.00181 -0.02822 -0.03782 256 LEU A CD2 
3910 N  N   . GLN A 277 ? 0.50195 0.29655 0.47055 -0.01435 -0.03926 -0.02499 257 GLN A N   
3911 C  CA  . GLN A 277 ? 0.62008 0.39504 0.58476 -0.01084 -0.04086 -0.02347 257 GLN A CA  
3912 C  C   . GLN A 277 ? 0.67669 0.42824 0.63381 -0.00839 -0.05144 -0.03373 257 GLN A C   
3913 O  O   . GLN A 277 ? 0.73880 0.47497 0.68619 0.00020  -0.05284 -0.03729 257 GLN A O   
3914 C  CB  . GLN A 277 ? 0.60537 0.37688 0.58364 -0.02039 -0.03869 -0.01114 257 GLN A CB  
3915 C  CG  . GLN A 277 ? 0.76411 0.52970 0.73714 -0.01470 -0.03342 -0.00423 257 GLN A CG  
3916 C  CD  . GLN A 277 ? 0.68836 0.45851 0.67247 -0.02327 -0.02762 0.00949  257 GLN A CD  
3917 O  OE1 . GLN A 277 ? 0.69944 0.48296 0.68114 -0.02035 -0.01928 0.01591  257 GLN A OE1 
3918 N  NE2 . GLN A 277 ? 0.74363 0.50335 0.74017 -0.03422 -0.03201 0.01408  257 GLN A NE2 
3927 N  N   . ARG A 278 ? 0.60624 0.35415 0.56702 -0.01501 -0.05955 -0.03913 258 ARG A N   
3928 C  CA  . ARG A 278 ? 0.62684 0.35043 0.57857 -0.01251 -0.07074 -0.04992 258 ARG A CA  
3929 C  C   . ARG A 278 ? 0.71158 0.43717 0.64502 -0.00185 -0.07225 -0.06278 258 ARG A C   
3930 O  O   . ARG A 278 ? 0.71224 0.41701 0.63439 0.00255  -0.08103 -0.07328 258 ARG A O   
3931 C  CB  . ARG A 278 ? 0.71169 0.42586 0.67657 -0.02567 -0.08121 -0.04961 258 ARG A CB  
3932 C  CG  . ARG A 278 ? 0.85481 0.58755 0.82612 -0.03166 -0.08299 -0.05097 258 ARG A CG  
3933 C  CD  . ARG A 278 ? 0.89061 0.61739 0.88135 -0.04622 -0.09218 -0.04713 258 ARG A CD  
3934 N  NE  . ARG A 278 ? 1.01157 0.74865 1.00652 -0.05111 -0.09923 -0.05198 258 ARG A NE  
3935 C  CZ  . ARG A 278 ? 0.98302 0.71509 0.96118 -0.04499 -0.10660 -0.06433 258 ARG A CZ  
3936 N  NH1 . ARG A 278 ? 1.00297 0.71892 0.95894 -0.03355 -0.10812 -0.07436 258 ARG A NH1 
3937 N  NH2 . ARG A 278 ? 0.85429 0.59779 0.83777 -0.05004 -0.11266 -0.06658 258 ARG A NH2 
3951 N  N   . ASP A 279 ? 0.61931 0.36829 0.54884 0.00246  -0.06401 -0.06220 259 ASP A N   
3952 C  CA  . ASP A 279 ? 0.59085 0.34370 0.50289 0.01220  -0.06395 -0.07289 259 ASP A CA  
3953 C  C   . ASP A 279 ? 0.58705 0.36206 0.49552 0.01969  -0.05195 -0.06942 259 ASP A C   
3954 O  O   . ASP A 279 ? 0.52297 0.31820 0.43575 0.01607  -0.04735 -0.06533 259 ASP A O   
3955 C  CB  . ASP A 279 ? 0.58439 0.34151 0.49561 0.00605  -0.07091 -0.07743 259 ASP A CB  
3956 C  CG  . ASP A 279 ? 0.66942 0.42525 0.55956 0.01590  -0.07239 -0.08894 259 ASP A CG  
3957 O  OD1 . ASP A 279 ? 0.65170 0.40833 0.52997 0.02756  -0.06577 -0.09247 259 ASP A OD1 
3958 O  OD2 . ASP A 279 ? 0.68642 0.44253 0.57216 0.01220  -0.07953 -0.09375 259 ASP A OD2 
3963 N  N   . PRO A 280 ? 0.64525 0.41675 0.54622 0.03050  -0.04732 -0.07131 260 PRO A N   
3964 C  CA  . PRO A 280 ? 0.64932 0.44238 0.54943 0.03694  -0.03665 -0.06747 260 PRO A CA  
3965 C  C   . PRO A 280 ? 0.55593 0.36354 0.44554 0.04172  -0.03328 -0.07315 260 PRO A C   
3966 O  O   . PRO A 280 ? 0.55341 0.38134 0.44534 0.04374  -0.02502 -0.06856 260 PRO A O   
3967 C  CB  . PRO A 280 ? 0.88689 0.66991 0.78223 0.04793  -0.03475 -0.06938 260 PRO A CB  
3968 C  CG  . PRO A 280 ? 0.91151 0.66786 0.80908 0.04439  -0.04348 -0.07009 260 PRO A CG  
3969 C  CD  . PRO A 280 ? 0.73478 0.48219 0.63046 0.03668  -0.05211 -0.07579 260 PRO A CD  
3977 N  N   . SER A 281 ? 0.55080 0.34800 0.42809 0.04363  -0.03961 -0.08279 261 SER A N   
3978 C  CA  . SER A 281 ? 0.55992 0.37046 0.42562 0.04763  -0.03625 -0.08710 261 SER A CA  
3979 C  C   . SER A 281 ? 0.49224 0.31968 0.36645 0.03785  -0.03517 -0.08021 261 SER A C   
3980 O  O   . SER A 281 ? 0.52694 0.36835 0.39354 0.04021  -0.03095 -0.08088 261 SER A O   
3981 C  CB  . SER A 281 ? 0.65971 0.45278 0.50737 0.05243  -0.04422 -0.09947 261 SER A CB  
3982 O  OG  . SER A 281 ? 0.64426 0.42848 0.49448 0.04237  -0.05466 -0.10072 261 SER A OG  
3988 N  N   . LEU A 282 ? 0.48149 0.30833 0.37158 0.02727  -0.03834 -0.07308 262 LEU A N   
3989 C  CA  . LEU A 282 ? 0.47811 0.32150 0.37815 0.01893  -0.03678 -0.06622 262 LEU A CA  
3990 C  C   . LEU A 282 ? 0.41346 0.27545 0.32162 0.01934  -0.02667 -0.05759 262 LEU A C   
3991 O  O   . LEU A 282 ? 0.39171 0.26750 0.30704 0.01389  -0.02454 -0.05223 262 LEU A O   
3992 C  CB  . LEU A 282 ? 0.44604 0.28259 0.36086 0.00787  -0.04390 -0.06236 262 LEU A CB  
3993 C  CG  . LEU A 282 ? 0.52354 0.34320 0.43468 0.00418  -0.05619 -0.06978 262 LEU A CG  
3994 C  CD1 . LEU A 282 ? 0.53452 0.35281 0.46554 -0.00791 -0.06156 -0.06355 262 LEU A CD1 
3995 C  CD2 . LEU A 282 ? 0.56345 0.38820 0.46106 0.00648  -0.05977 -0.07599 262 LEU A CD2 
4007 N  N   . LEU A 283 ? 0.40742 0.26970 0.31469 0.02594  -0.02112 -0.05635 263 LEU A N   
4008 C  CA  . LEU A 283 ? 0.39677 0.27519 0.31183 0.02581  -0.01323 -0.04847 263 LEU A CA  
4009 C  C   . LEU A 283 ? 0.36577 0.26224 0.27735 0.02708  -0.00817 -0.04767 263 LEU A C   
4010 O  O   . LEU A 283 ? 0.35237 0.26092 0.27241 0.02207  -0.00505 -0.04105 263 LEU A O   
4011 C  CB  . LEU A 283 ? 0.41429 0.28836 0.32830 0.03359  -0.01000 -0.04817 263 LEU A CB  
4012 C  CG  . LEU A 283 ? 0.45418 0.34237 0.37583 0.03372  -0.00355 -0.04031 263 LEU A CG  
4013 C  CD1 . LEU A 283 ? 0.42351 0.31163 0.35568 0.02474  -0.00395 -0.03242 263 LEU A CD1 
4014 C  CD2 . LEU A 283 ? 0.51182 0.39560 0.43175 0.04263  -0.00179 -0.04084 263 LEU A CD2 
4026 N  N   . PRO A 284 ? 0.38774 0.28642 0.28694 0.03325  -0.00707 -0.05370 264 PRO A N   
4027 C  CA  . PRO A 284 ? 0.38353 0.29943 0.28063 0.03295  -0.00201 -0.05102 264 PRO A CA  
4028 C  C   . PRO A 284 ? 0.35725 0.27782 0.25931 0.02429  -0.00515 -0.04724 264 PRO A C   
4029 O  O   . PRO A 284 ? 0.34951 0.28317 0.25836 0.02114  -0.00112 -0.04110 264 PRO A O   
4030 C  CB  . PRO A 284 ? 0.38552 0.30000 0.26660 0.04069  -0.00089 -0.05835 264 PRO A CB  
4031 C  CG  . PRO A 284 ? 0.44559 0.34680 0.32283 0.04844  -0.00190 -0.06414 264 PRO A CG  
4032 C  CD  . PRO A 284 ? 0.44695 0.33356 0.33331 0.04184  -0.00892 -0.06252 264 PRO A CD  
4040 N  N   . GLY A 285 ? 0.38707 0.29675 0.28692 0.02045  -0.01301 -0.05085 265 GLY A N   
4041 C  CA  . GLY A 285 ? 0.37781 0.29251 0.28475 0.01274  -0.01669 -0.04712 265 GLY A CA  
4042 C  C   . GLY A 285 ? 0.34177 0.26102 0.26550 0.00670  -0.01508 -0.03994 265 GLY A C   
4043 O  O   . GLY A 285 ? 0.31302 0.24270 0.24376 0.00261  -0.01379 -0.03505 265 GLY A O   
4047 N  N   . ALA A 286 ? 0.33465 0.24624 0.26418 0.00672  -0.01451 -0.03884 266 ALA A N   
4048 C  CA  . ALA A 286 ? 0.29134 0.20771 0.23457 0.00184  -0.01151 -0.03145 266 ALA A CA  
4049 C  C   . ALA A 286 ? 0.31074 0.24076 0.25499 0.00391  -0.00427 -0.02683 266 ALA A C   
4050 O  O   . ALA A 286 ? 0.28292 0.22083 0.23570 -0.00019 -0.00223 -0.02167 266 ALA A O   
4051 C  CB  . ALA A 286 ? 0.34168 0.24626 0.28857 0.00199  -0.01185 -0.03026 266 ALA A CB  
4057 N  N   . ILE A 287 ? 0.31066 0.24346 0.24719 0.01046  -0.00047 -0.02868 267 ILE A N   
4058 C  CA  . ILE A 287 ? 0.29532 0.24070 0.23396 0.01185  0.00523  -0.02442 267 ILE A CA  
4059 C  C   . ILE A 287 ? 0.29576 0.25094 0.23457 0.00868  0.00549  -0.02286 267 ILE A C   
4060 O  O   . ILE A 287 ? 0.27452 0.23740 0.21903 0.00630  0.00796  -0.01834 267 ILE A O   
4061 C  CB  . ILE A 287 ? 0.31891 0.26697 0.25165 0.01929  0.00865  -0.02669 267 ILE A CB  
4062 C  CG1 . ILE A 287 ? 0.35813 0.29629 0.29192 0.02298  0.00819  -0.02699 267 ILE A CG1 
4063 C  CG2 . ILE A 287 ? 0.37007 0.33269 0.30543 0.01980  0.01328  -0.02286 267 ILE A CG2 
4064 C  CD1 . ILE A 287 ? 0.38155 0.31699 0.32235 0.01958  0.00847  -0.02152 267 ILE A CD1 
4076 N  N   . GLU A 288 ? 0.27075 0.22435 0.20217 0.00894  0.00242  -0.02668 268 GLU A N   
4077 C  CA  . GLU A 288 ? 0.29418 0.25551 0.22478 0.00610  0.00191  -0.02456 268 GLU A CA  
4078 C  C   . GLU A 288 ? 0.28064 0.24241 0.22168 0.00032  -0.00115 -0.02134 268 GLU A C   
4079 O  O   . GLU A 288 ? 0.26311 0.23240 0.20811 -0.00162 0.00034  -0.01753 268 GLU A O   
4080 C  CB  . GLU A 288 ? 0.30187 0.26034 0.22015 0.00797  -0.00119 -0.02897 268 GLU A CB  
4081 C  CG  . GLU A 288 ? 0.31082 0.27144 0.21861 0.01441  0.00335  -0.03184 268 GLU A CG  
4082 C  CD  . GLU A 288 ? 0.31793 0.29145 0.22957 0.01534  0.01020  -0.02696 268 GLU A CD  
4083 O  OE1 . GLU A 288 ? 0.34400 0.32450 0.25728 0.01173  0.01078  -0.02262 268 GLU A OE1 
4084 O  OE2 . GLU A 288 ? 0.33593 0.31212 0.25030 0.01941  0.01421  -0.02719 268 GLU A OE2 
4091 N  N   . GLU A 289 ? 0.26432 0.21826 0.21113 -0.00236 -0.00522 -0.02257 269 GLU A N   
4092 C  CA  . GLU A 289 ? 0.27424 0.23122 0.23361 -0.00751 -0.00693 -0.01889 269 GLU A CA  
4093 C  C   . GLU A 289 ? 0.28411 0.24628 0.25123 -0.00792 -0.00088 -0.01377 269 GLU A C   
4094 O  O   . GLU A 289 ? 0.27018 0.23889 0.24486 -0.01004 0.00023  -0.01044 269 GLU A O   
4095 C  CB  . GLU A 289 ? 0.29833 0.24681 0.26355 -0.01122 -0.01323 -0.02105 269 GLU A CB  
4096 C  CG  . GLU A 289 ? 0.29301 0.24685 0.27409 -0.01676 -0.01524 -0.01713 269 GLU A CG  
4097 C  CD  . GLU A 289 ? 0.28779 0.24747 0.27008 -0.01793 -0.02013 -0.01750 269 GLU A CD  
4098 O  OE1 . GLU A 289 ? 0.31170 0.27371 0.28257 -0.01466 -0.01951 -0.01858 269 GLU A OE1 
4099 O  OE2 . GLU A 289 ? 0.28264 0.24509 0.27819 -0.02221 -0.02468 -0.01610 269 GLU A OE2 
4106 N  N   . MET A 290 ? 0.25480 0.21410 0.21904 -0.00507 0.00290  -0.01327 270 MET A N   
4107 C  CA  . MET A 290 ? 0.25005 0.21359 0.21820 -0.00466 0.00808  -0.00874 270 MET A CA  
4108 C  C   . MET A 290 ? 0.23196 0.20432 0.19767 -0.00338 0.01032  -0.00758 270 MET A C   
4109 O  O   . MET A 290 ? 0.23590 0.21266 0.20628 -0.00447 0.01256  -0.00452 270 MET A O   
4110 C  CB  . MET A 290 ? 0.26362 0.22143 0.22730 -0.00107 0.01008  -0.00885 270 MET A CB  
4111 C  CG  . MET A 290 ? 0.24924 0.19657 0.21661 -0.00316 0.00802  -0.00849 270 MET A CG  
4112 S  SD  . MET A 290 ? 0.40196 0.34032 0.36203 0.00266  0.00873  -0.00975 270 MET A SD  
4113 C  CE  . MET A 290 ? 0.33763 0.28243 0.29770 0.00444  0.01368  -0.00461 270 MET A CE  
4123 N  N   . LEU A 291 ? 0.25057 0.22518 0.20892 -0.00112 0.00972  -0.01001 271 LEU A N   
4124 C  CA  . LEU A 291 ? 0.21423 0.19630 0.17086 -0.00093 0.01119  -0.00840 271 LEU A CA  
4125 C  C   . LEU A 291 ? 0.22254 0.20682 0.18274 -0.00396 0.00874  -0.00708 271 LEU A C   
4126 O  O   . LEU A 291 ? 0.22690 0.21476 0.19009 -0.00458 0.00999  -0.00465 271 LEU A O   
4127 C  CB  . LEU A 291 ? 0.23333 0.21810 0.18230 0.00164  0.01184  -0.01035 271 LEU A CB  
4128 C  CG  . LEU A 291 ? 0.24341 0.22965 0.19073 0.00574  0.01488  -0.01101 271 LEU A CG  
4129 C  CD1 . LEU A 291 ? 0.24594 0.23412 0.18627 0.00934  0.01603  -0.01394 271 LEU A CD1 
4130 C  CD2 . LEU A 291 ? 0.26432 0.25742 0.21547 0.00532  0.01695  -0.00762 271 LEU A CD2 
4142 N  N   . ARG A 292 ? 0.23188 0.21329 0.19134 -0.00538 0.00443  -0.00902 272 ARG A N   
4143 C  CA  . ARG A 292 ? 0.23538 0.21903 0.19935 -0.00767 0.00110  -0.00757 272 ARG A CA  
4144 C  C   . ARG A 292 ? 0.23505 0.22117 0.21002 -0.00881 0.00289  -0.00499 272 ARG A C   
4145 O  O   . ARG A 292 ? 0.23077 0.22035 0.20878 -0.00867 0.00321  -0.00302 272 ARG A O   
4146 C  CB  . ARG A 292 ? 0.22413 0.20375 0.18699 -0.00908 -0.00510 -0.01029 272 ARG A CB  
4147 C  CG  . ARG A 292 ? 0.22506 0.20755 0.19297 -0.01078 -0.00950 -0.00858 272 ARG A CG  
4148 C  CD  . ARG A 292 ? 0.25216 0.23119 0.22082 -0.01257 -0.01755 -0.01115 272 ARG A CD  
4149 N  NE  . ARG A 292 ? 0.26890 0.24668 0.24983 -0.01528 -0.01927 -0.01181 272 ARG A NE  
4150 C  CZ  . ARG A 292 ? 0.27030 0.25358 0.26679 -0.01745 -0.01990 -0.00911 272 ARG A CZ  
4151 N  NH1 . ARG A 292 ? 0.25034 0.23983 0.25183 -0.01639 -0.01968 -0.00635 272 ARG A NH1 
4152 N  NH2 . ARG A 292 ? 0.25637 0.23897 0.26442 -0.02063 -0.02057 -0.00889 272 ARG A NH2 
4166 N  N   . TRP A 293 ? 0.22668 0.21054 0.20748 -0.00971 0.00426  -0.00483 273 TRP A N   
4167 C  CA  . TRP A 293 ? 0.23247 0.21962 0.22410 -0.01080 0.00688  -0.00196 273 TRP A CA  
4168 C  C   . TRP A 293 ? 0.23917 0.22885 0.22849 -0.00827 0.01219  -0.00000 273 TRP A C   
4169 O  O   . TRP A 293 ? 0.23204 0.22570 0.22703 -0.00760 0.01390  0.00155  273 TRP A O   
4170 C  CB  . TRP A 293 ? 0.25152 0.23486 0.24874 -0.01296 0.00763  -0.00125 273 TRP A CB  
4171 C  CG  . TRP A 293 ? 0.25084 0.23898 0.26063 -0.01475 0.01089  0.00246  273 TRP A CG  
4172 C  CD1 . TRP A 293 ? 0.25811 0.24856 0.26869 -0.01314 0.01766  0.00575  273 TRP A CD1 
4173 C  CD2 . TRP A 293 ? 0.25139 0.24383 0.27516 -0.01821 0.00772  0.00345  273 TRP A CD2 
4174 N  NE1 . TRP A 293 ? 0.27706 0.27354 0.30105 -0.01512 0.02024  0.00901  273 TRP A NE1 
4175 C  CE2 . TRP A 293 ? 0.26886 0.26747 0.30280 -0.01848 0.01407  0.00780  273 TRP A CE2 
4176 C  CE3 . TRP A 293 ? 0.24622 0.23839 0.27487 -0.02090 -0.00028 0.00106  273 TRP A CE3 
4177 C  CZ2 . TRP A 293 ? 0.29384 0.30007 0.34499 -0.02147 0.01349  0.01023  273 TRP A CZ2 
4178 C  CZ3 . TRP A 293 ? 0.28661 0.28548 0.33277 -0.02431 -0.00232 0.00328  273 TRP A CZ3 
4179 C  CH2 . TRP A 293 ? 0.27576 0.28230 0.33411 -0.02469 0.00494  0.00803  273 TRP A CH2 
4190 N  N   . THR A 294 ? 0.21538 0.20261 0.19674 -0.00640 0.01446  -0.00036 274 THR A N   
4191 C  CA  . THR A 294 ? 0.22378 0.21195 0.20219 -0.00412 0.01847  0.00118  274 THR A CA  
4192 C  C   . THR A 294 ? 0.24468 0.23497 0.21896 -0.00303 0.01735  0.00055  274 THR A C   
4193 O  O   . THR A 294 ? 0.24817 0.23881 0.22141 -0.00135 0.01931  0.00118  274 THR A O   
4194 C  CB  . THR A 294 ? 0.23229 0.21687 0.20488 -0.00242 0.02028  0.00143  274 THR A CB  
4195 O  OG1 . THR A 294 ? 0.24852 0.23275 0.21608 -0.00157 0.01800  -0.00081 274 THR A OG1 
4196 C  CG2 . THR A 294 ? 0.25543 0.23587 0.23211 -0.00376 0.02173  0.00319  274 THR A CG2 
4204 N  N   . ALA A 295 ? 0.23241 0.22340 0.20361 -0.00396 0.01425  -0.00056 275 ALA A N   
4205 C  CA  . ALA A 295 ? 0.25832 0.25078 0.22648 -0.00412 0.01284  -0.00015 275 ALA A CA  
4206 C  C   . ALA A 295 ? 0.25421 0.24617 0.22030 -0.00261 0.01437  0.00016  275 ALA A C   
4207 O  O   . ALA A 295 ? 0.23915 0.22975 0.20617 -0.00195 0.01385  0.00020  275 ALA A O   
4208 C  CB  . ALA A 295 ? 0.26637 0.25885 0.23790 -0.00514 0.00995  0.00046  275 ALA A CB  
4214 N  N   . PRO A 296 ? 0.22419 0.21662 0.18691 -0.00150 0.01554  -0.00001 276 PRO A N   
4215 C  CA  . PRO A 296 ? 0.26007 0.25118 0.21964 0.00021  0.01588  -0.00007 276 PRO A CA  
4216 C  C   . PRO A 296 ? 0.24224 0.23286 0.20108 -0.00101 0.01286  -0.00035 276 PRO A C   
4217 O  O   . PRO A 296 ? 0.27084 0.25788 0.22692 0.00068  0.01249  -0.00135 276 PRO A O   
4218 C  CB  . PRO A 296 ? 0.29871 0.29148 0.25591 0.00149  0.01607  0.00001  276 PRO A CB  
4219 C  CG  . PRO A 296 ? 0.28310 0.27583 0.24180 0.00155  0.01734  -0.00017 276 PRO A CG  
4220 C  CD  . PRO A 296 ? 0.25293 0.24643 0.21418 -0.00090 0.01613  -0.00052 276 PRO A CD  
4228 N  N   . VAL A 297 ? 0.23679 0.23006 0.19729 -0.00382 0.01076  0.00062  277 VAL A N   
4229 C  CA  . VAL A 297 ? 0.21698 0.20846 0.17782 -0.00613 0.00736  0.00132  277 VAL A CA  
4230 C  C   . VAL A 297 ? 0.24950 0.23730 0.21185 -0.00615 0.00639  0.00157  277 VAL A C   
4231 O  O   . VAL A 297 ? 0.25323 0.24280 0.21685 -0.00742 0.00624  0.00289  277 VAL A O   
4232 C  CB  . VAL A 297 ? 0.22435 0.22123 0.18695 -0.00956 0.00635  0.00365  277 VAL A CB  
4233 C  CG1 . VAL A 297 ? 0.29282 0.28643 0.25663 -0.01301 0.00252  0.00537  277 VAL A CG1 
4234 C  CG2 . VAL A 297 ? 0.27081 0.27301 0.23437 -0.00876 0.00690  0.00335  277 VAL A CG2 
4244 N  N   . LYS A 298 ? 0.23926 0.22181 0.20092 -0.00393 0.00554  -0.00004 278 LYS A N   
4245 C  CA  . LYS A 298 ? 0.23276 0.21264 0.19748 -0.00245 0.00483  -0.00011 278 LYS A CA  
4246 C  C   . LYS A 298 ? 0.25892 0.23500 0.22404 -0.00509 0.00024  0.00186  278 LYS A C   
4247 O  O   . LYS A 298 ? 0.25016 0.22520 0.21809 -0.00460 -0.00139 0.00301  278 LYS A O   
4248 C  CB  . LYS A 298 ? 0.23296 0.20901 0.19653 0.00219  0.00654  -0.00280 278 LYS A CB  
4249 C  CG  . LYS A 298 ? 0.25250 0.23186 0.21486 0.00471  0.01185  -0.00345 278 LYS A CG  
4250 C  CD  . LYS A 298 ? 0.24389 0.22876 0.21224 0.00331  0.01414  -0.00163 278 LYS A CD  
4251 C  CE  . LYS A 298 ? 0.27005 0.25681 0.23762 0.00499  0.01926  -0.00119 278 LYS A CE  
4252 N  NZ  . LYS A 298 ? 0.25784 0.24835 0.23188 0.00276  0.02046  0.00047  278 LYS A NZ  
4266 N  N   . ASN A 299 ? 0.25311 0.22673 0.21605 -0.00803 -0.00246 0.00270  279 ASN A N   
4267 C  CA  . ASN A 299 ? 0.25482 0.22384 0.21823 -0.01147 -0.00677 0.00577  279 ASN A CA  
4268 C  C   . ASN A 299 ? 0.26474 0.23497 0.22822 -0.01637 -0.00861 0.00779  279 ASN A C   
4269 O  O   . ASN A 299 ? 0.25430 0.22679 0.21740 -0.01609 -0.00816 0.00566  279 ASN A O   
4270 C  CB  . ASN A 299 ? 0.26956 0.22872 0.23288 -0.00841 -0.01019 0.00390  279 ASN A CB  
4271 C  CG  . ASN A 299 ? 0.29063 0.24474 0.25071 -0.00523 -0.01049 -0.00071 279 ASN A CG  
4272 O  OD1 . ASN A 299 ? 0.31019 0.26050 0.26813 -0.00807 -0.01385 -0.00122 279 ASN A OD1 
4273 N  ND2 . ASN A 299 ? 0.27824 0.23280 0.23779 0.00069  -0.00693 -0.00405 279 ASN A ND2 
4280 N  N   . MET A 300 ? 0.25587 0.22528 0.22036 -0.02104 -0.01076 0.01256  280 MET A N   
4281 C  CA  . MET A 300 ? 0.25491 0.22428 0.22205 -0.02706 -0.01348 0.01607  280 MET A CA  
4282 C  C   . MET A 300 ? 0.25821 0.21672 0.22492 -0.02952 -0.01843 0.01926  280 MET A C   
4283 O  O   . MET A 300 ? 0.28704 0.24318 0.25144 -0.02795 -0.01835 0.02132  280 MET A O   
4284 C  CB  . MET A 300 ? 0.26519 0.24638 0.23402 -0.03041 -0.00924 0.02043  280 MET A CB  
4285 C  CG  . MET A 300 ? 0.27741 0.26965 0.24813 -0.02867 -0.00499 0.01825  280 MET A CG  
4286 S  SD  . MET A 300 ? 0.25808 0.25360 0.23496 -0.03118 -0.00799 0.01709  280 MET A SD  
4287 C  CE  . MET A 300 ? 0.26572 0.27122 0.24236 -0.02597 -0.00319 0.01377  280 MET A CE  
4297 N  N   . CYS A 301 ? 0.28564 0.23717 0.25478 -0.03375 -0.02351 0.02010  281 CYS A N   
4298 C  CA  . CYS A 301 ? 0.27861 0.21740 0.24734 -0.03637 -0.02901 0.02349  281 CYS A CA  
4299 C  C   . CYS A 301 ? 0.32456 0.26713 0.29632 -0.04455 -0.02876 0.03247  281 CYS A C   
4300 O  O   . CYS A 301 ? 0.28979 0.24448 0.26596 -0.04887 -0.02527 0.03535  281 CYS A O   
4301 C  CB  . CYS A 301 ? 0.31408 0.23952 0.28300 -0.03674 -0.03594 0.01953  281 CYS A CB  
4302 S  SG  . CYS A 301 ? 0.37916 0.29757 0.34210 -0.02616 -0.03586 0.00957  281 CYS A SG  
4308 N  N   . ARG A 302 ? 0.29713 0.22913 0.26671 -0.04628 -0.03241 0.03724  282 ARG A N   
4309 C  CA  . ARG A 302 ? 0.29572 0.22743 0.26705 -0.05450 -0.03301 0.04702  282 ARG A CA  
4310 C  C   . ARG A 302 ? 0.36778 0.28028 0.33976 -0.05727 -0.04159 0.04884  282 ARG A C   
4311 O  O   . ARG A 302 ? 0.38093 0.28111 0.34910 -0.05080 -0.04568 0.04406  282 ARG A O   
4312 C  CB  . ARG A 302 ? 0.31556 0.25182 0.28016 -0.05343 -0.02896 0.05279  282 ARG A CB  
4313 C  CG  . ARG A 302 ? 0.28974 0.24224 0.25173 -0.05012 -0.02122 0.05071  282 ARG A CG  
4314 C  CD  . ARG A 302 ? 0.29854 0.26514 0.26599 -0.05567 -0.01590 0.05431  282 ARG A CD  
4315 N  NE  . ARG A 302 ? 0.27376 0.25458 0.23802 -0.05178 -0.00858 0.05206  282 ARG A NE  
4316 C  CZ  . ARG A 302 ? 0.28522 0.27428 0.25306 -0.04821 -0.00588 0.04563  282 ARG A CZ  
4317 N  NH1 . ARG A 302 ? 0.26991 0.25485 0.24297 -0.04715 -0.00969 0.04019  282 ARG A NH1 
4318 N  NH2 . ARG A 302 ? 0.28366 0.28447 0.24856 -0.04530 0.00057  0.04471  282 ARG A NH2 
4332 N  N   . VAL A 303 ? 0.32723 0.23669 0.30473 -0.06670 -0.04447 0.05593  283 VAL A N   
4333 C  CA  . VAL A 303 ? 0.36610 0.25511 0.34416 -0.07023 -0.05339 0.05850  283 VAL A CA  
4334 C  C   . VAL A 303 ? 0.36957 0.25470 0.34423 -0.07479 -0.05284 0.07007  283 VAL A C   
4335 O  O   . VAL A 303 ? 0.37508 0.27393 0.35105 -0.08057 -0.04645 0.07829  283 VAL A O   
4336 C  CB  . VAL A 303 ? 0.37332 0.25826 0.36048 -0.07838 -0.05909 0.05831  283 VAL A CB  
4337 C  CG1 . VAL A 303 ? 0.40815 0.30835 0.40463 -0.08932 -0.05461 0.06859  283 VAL A CG1 
4338 C  CG2 . VAL A 303 ? 0.39691 0.25698 0.38314 -0.08028 -0.06961 0.05841  283 VAL A CG2 
4348 N  N   . LEU A 304 ? 0.37717 0.24350 0.34665 -0.07153 -0.05936 0.07099  284 LEU A N   
4349 C  CA  . LEU A 304 ? 0.38560 0.24571 0.34975 -0.07494 -0.06001 0.08236  284 LEU A CA  
4350 C  C   . LEU A 304 ? 0.40546 0.25836 0.37567 -0.08741 -0.06327 0.09274  284 LEU A C   
4351 O  O   . LEU A 304 ? 0.42553 0.26422 0.40173 -0.09095 -0.07103 0.09012  284 LEU A O   
4352 C  CB  . LEU A 304 ? 0.41237 0.25445 0.37021 -0.06673 -0.06683 0.08010  284 LEU A CB  
4353 C  CG  . LEU A 304 ? 0.39992 0.25047 0.35147 -0.05654 -0.06331 0.07587  284 LEU A CG  
4354 C  CD1 . LEU A 304 ? 0.41917 0.27949 0.36313 -0.05952 -0.05837 0.08575  284 LEU A CD1 
4355 C  CD2 . LEU A 304 ? 0.39626 0.26123 0.35090 -0.05060 -0.05795 0.06470  284 LEU A CD2 
4367 N  N   . THR A 305 ? 0.41145 0.27424 0.38011 -0.09429 -0.05729 0.10457  285 THR A N   
4368 C  CA  . THR A 305 ? 0.44979 0.30691 0.42524 -0.10706 -0.05942 0.11650  285 THR A CA  
4369 C  C   . THR A 305 ? 0.46060 0.29558 0.42877 -0.10892 -0.06617 0.12586  285 THR A C   
4370 O  O   . THR A 305 ? 0.48739 0.31898 0.46179 -0.11644 -0.06752 0.13256  285 THR A O   
4371 C  CB  . THR A 305 ? 0.43807 0.31831 0.41641 -0.11402 -0.04834 0.12575  285 THR A CB  
4372 O  OG1 . THR A 305 ? 0.46282 0.34778 0.42698 -0.10933 -0.04251 0.13102  285 THR A OG1 
4373 C  CG2 . THR A 305 ? 0.43473 0.33608 0.42129 -0.11185 -0.04242 0.11685  285 THR A CG2 
4381 N  N   . ALA A 306 ? 0.46445 0.29052 0.42149 -0.09860 -0.06886 0.12249  286 ALA A N   
4382 C  CA  . ALA A 306 ? 0.48849 0.29576 0.43852 -0.09701 -0.07527 0.12890  286 ALA A CA  
4383 C  C   . ALA A 306 ? 0.50069 0.29747 0.44338 -0.08425 -0.08069 0.12089  286 ALA A C   
4384 O  O   . ALA A 306 ? 0.49791 0.30979 0.43957 -0.07621 -0.07571 0.11139  286 ALA A O   
4385 C  CB  . ALA A 306 ? 0.52942 0.34642 0.47131 -0.10038 -0.06827 0.14101  286 ALA A CB  
4391 N  N   . ASP A 307 ? 0.52409 0.30065 0.46413 -0.08037 -0.08919 0.12208  287 ASP A N   
4392 C  CA  . ASP A 307 ? 0.51929 0.28699 0.45298 -0.06809 -0.09433 0.11723  287 ASP A CA  
4393 C  C   . ASP A 307 ? 0.54258 0.32459 0.46608 -0.06534 -0.08884 0.12273  287 ASP A C   
4394 O  O   . ASP A 307 ? 0.56619 0.35403 0.48363 -0.07202 -0.08442 0.13354  287 ASP A O   
4395 C  CB  . ASP A 307 ? 0.51741 0.26463 0.45052 -0.06432 -0.10312 0.11849  287 ASP A CB  
4396 C  CG  . ASP A 307 ? 0.57951 0.31165 0.52094 -0.06579 -0.10928 0.11176  287 ASP A CG  
4397 O  OD1 . ASP A 307 ? 0.53774 0.27229 0.48490 -0.06636 -0.10870 0.10314  287 ASP A OD1 
4398 O  OD2 . ASP A 307 ? 0.70782 0.42454 0.64913 -0.06639 -0.11529 0.11518  287 ASP A OD2 
4403 N  N   . THR A 308 ? 0.48903 0.28015 0.41160 -0.05437 -0.08794 0.11317  288 THR A N   
4404 C  CA  . THR A 308 ? 0.51180 0.31652 0.42470 -0.05149 -0.08380 0.11656  288 THR A CA  
4405 C  C   . THR A 308 ? 0.48101 0.28773 0.39533 -0.03892 -0.08765 0.10729  288 THR A C   
4406 O  O   . THR A 308 ? 0.46406 0.27130 0.38793 -0.03271 -0.08840 0.09609  288 THR A O   
4407 C  CB  . THR A 308 ? 0.49370 0.32127 0.40644 -0.05648 -0.07254 0.11520  288 THR A CB  
4408 O  OG1 . THR A 308 ? 0.55153 0.38859 0.45126 -0.05623 -0.06870 0.12165  288 THR A OG1 
4409 C  CG2 . THR A 308 ? 0.45203 0.29236 0.37303 -0.05018 -0.06896 0.10110  288 THR A CG2 
4417 N  N   . GLU A 309 ? 0.45251 0.26003 0.35716 -0.03528 -0.09045 0.11265  289 GLU A N   
4418 C  CA  . GLU A 309 ? 0.42954 0.24318 0.33647 -0.02452 -0.09383 0.10514  289 GLU A CA  
4419 C  C   . GLU A 309 ? 0.45056 0.28605 0.35460 -0.02493 -0.08567 0.10060  289 GLU A C   
4420 O  O   . GLU A 309 ? 0.48390 0.32478 0.37532 -0.02934 -0.08257 0.10784  289 GLU A O   
4421 C  CB  . GLU A 309 ? 0.46954 0.27127 0.36769 -0.02036 -0.10316 0.11336  289 GLU A CB  
4422 C  CG  . GLU A 309 ? 0.50355 0.31418 0.40467 -0.01039 -0.10722 0.10696  289 GLU A CG  
4423 C  CD  . GLU A 309 ? 0.50592 0.31396 0.42297 -0.00079 -0.11125 0.09695  289 GLU A CD  
4424 O  OE1 . GLU A 309 ? 0.50007 0.29434 0.42334 -0.00015 -0.11323 0.09523  289 GLU A OE1 
4425 O  OE2 . GLU A 309 ? 0.52342 0.34312 0.44686 0.00664  -0.11290 0.09079  289 GLU A OE2 
4432 N  N   . PHE A 310 ? 0.40794 0.25485 0.32261 -0.02009 -0.08220 0.08894  290 PHE A N   
4433 C  CA  . PHE A 310 ? 0.37796 0.24394 0.29178 -0.02118 -0.07404 0.08365  290 PHE A CA  
4434 C  C   . PHE A 310 ? 0.36204 0.23690 0.28267 -0.01276 -0.07617 0.07520  290 PHE A C   
4435 O  O   . PHE A 310 ? 0.36275 0.23942 0.29580 -0.00781 -0.07575 0.06707  290 PHE A O   
4436 C  CB  . PHE A 310 ? 0.38802 0.26041 0.30889 -0.02581 -0.06634 0.07875  290 PHE A CB  
4437 C  CG  . PHE A 310 ? 0.34694 0.23729 0.26623 -0.02732 -0.05789 0.07446  290 PHE A CG  
4438 C  CD1 . PHE A 310 ? 0.38211 0.27880 0.28945 -0.03159 -0.05396 0.08076  290 PHE A CD1 
4439 C  CD2 . PHE A 310 ? 0.34773 0.24739 0.27628 -0.02388 -0.05401 0.06450  290 PHE A CD2 
4440 C  CE1 . PHE A 310 ? 0.40706 0.31888 0.31243 -0.03202 -0.04646 0.07624  290 PHE A CE1 
4441 C  CE2 . PHE A 310 ? 0.34974 0.26408 0.27669 -0.02501 -0.04687 0.06079  290 PHE A CE2 
4442 C  CZ  . PHE A 310 ? 0.35747 0.27734 0.27310 -0.02886 -0.04342 0.06637  290 PHE A CZ  
4452 N  N   . HIS A 311 ? 0.39227 0.27318 0.30458 -0.01133 -0.07828 0.07714  291 HIS A N   
4453 C  CA  . HIS A 311 ? 0.38997 0.28045 0.30960 -0.00467 -0.08121 0.06997  291 HIS A CA  
4454 C  C   . HIS A 311 ? 0.37564 0.26096 0.30980 0.00303  -0.08735 0.06620  291 HIS A C   
4455 O  O   . HIS A 311 ? 0.38068 0.27562 0.32836 0.00761  -0.08518 0.05798  291 HIS A O   
4456 C  CB  . HIS A 311 ? 0.37297 0.27859 0.29780 -0.00578 -0.07289 0.06175  291 HIS A CB  
4457 C  CG  . HIS A 311 ? 0.37960 0.29220 0.29058 -0.01001 -0.06889 0.06366  291 HIS A CG  
4458 N  ND1 . HIS A 311 ? 0.41438 0.32949 0.31662 -0.00791 -0.07413 0.06423  291 HIS A ND1 
4459 C  CD2 . HIS A 311 ? 0.39743 0.31442 0.30102 -0.01569 -0.06056 0.06524  291 HIS A CD2 
4460 C  CE1 . HIS A 311 ? 0.46603 0.38583 0.35448 -0.01165 -0.06871 0.06548  291 HIS A CE1 
4461 N  NE2 . HIS A 311 ? 0.42480 0.34667 0.31469 -0.01621 -0.05997 0.06632  291 HIS A NE2 
4469 N  N   . GLY A 312 ? 0.38918 0.25905 0.32017 0.00468  -0.09478 0.07285  292 GLY A N   
4470 C  CA  . GLY A 312 ? 0.38950 0.25247 0.33234 0.01330  -0.10203 0.07056  292 GLY A CA  
4471 C  C   . GLY A 312 ? 0.41934 0.27306 0.37094 0.01553  -0.10000 0.06638  292 GLY A C   
4472 O  O   . GLY A 312 ? 0.42322 0.26955 0.38366 0.02375  -0.10590 0.06443  292 GLY A O   
4476 N  N   . THR A 313 ? 0.37953 0.23306 0.32870 0.00907  -0.09252 0.06469  293 THR A N   
4477 C  CA  . THR A 313 ? 0.37882 0.22314 0.33446 0.01096  -0.09115 0.05955  293 THR A CA  
4478 C  C   . THR A 313 ? 0.41258 0.24134 0.35952 0.00257  -0.09249 0.06670  293 THR A C   
4479 O  O   . THR A 313 ? 0.39428 0.22838 0.33372 -0.00651 -0.08767 0.07161  293 THR A O   
4480 C  CB  . THR A 313 ? 0.37880 0.23728 0.34114 0.01108  -0.08198 0.05017  293 THR A CB  
4481 O  OG1 . THR A 313 ? 0.37588 0.24772 0.34851 0.01876  -0.08104 0.04432  293 THR A OG1 
4482 C  CG2 . THR A 313 ? 0.37667 0.22429 0.34232 0.01289  -0.08113 0.04467  293 THR A CG2 
4490 N  N   . ALA A 314 ? 0.38567 0.19546 0.33463 0.00573  -0.09886 0.06704  294 ALA A N   
4491 C  CA  . ALA A 314 ? 0.41439 0.20703 0.35744 -0.00254 -0.10152 0.07371  294 ALA A CA  
4492 C  C   . ALA A 314 ? 0.44486 0.24113 0.39115 -0.00753 -0.09536 0.06728  294 ALA A C   
4493 O  O   . ALA A 314 ? 0.42194 0.21920 0.37474 -0.00073 -0.09392 0.05685  294 ALA A O   
4494 C  CB  . ALA A 314 ? 0.45438 0.22343 0.39886 0.00336  -0.11151 0.07499  294 ALA A CB  
4500 N  N   . LEU A 315 ? 0.42636 0.22571 0.36815 -0.01893 -0.09153 0.07359  295 LEU A N   
4501 C  CA  . LEU A 315 ? 0.40810 0.21112 0.35353 -0.02464 -0.08697 0.06866  295 LEU A CA  
4502 C  C   . LEU A 315 ? 0.43848 0.22424 0.38291 -0.03409 -0.09192 0.07579  295 LEU A C   
4503 O  O   . LEU A 315 ? 0.47575 0.25336 0.41504 -0.03973 -0.09504 0.08741  295 LEU A O   
4504 C  CB  . LEU A 315 ? 0.41203 0.23730 0.35654 -0.02988 -0.07749 0.06894  295 LEU A CB  
4505 C  CG  . LEU A 315 ? 0.39075 0.23325 0.33645 -0.02246 -0.07257 0.06262  295 LEU A CG  
4506 C  CD1 . LEU A 315 ? 0.39214 0.25317 0.33477 -0.02842 -0.06420 0.06464  295 LEU A CD1 
4507 C  CD2 . LEU A 315 ? 0.38626 0.23045 0.33905 -0.01453 -0.07141 0.05098  295 LEU A CD2 
4519 N  N   . CYS A 316 ? 0.46423 0.24339 0.41325 -0.03580 -0.09329 0.06898  296 CYS A N   
4520 C  CA  . CYS A 316 ? 0.49277 0.25316 0.44291 -0.04457 -0.09989 0.07405  296 CYS A CA  
4521 C  C   . CYS A 316 ? 0.47172 0.24362 0.42619 -0.05640 -0.09516 0.07656  296 CYS A C   
4522 O  O   . CYS A 316 ? 0.45024 0.23813 0.40766 -0.05500 -0.08923 0.06874  296 CYS A O   
4523 C  CB  . CYS A 316 ? 0.57975 0.31948 0.53150 -0.03756 -0.10777 0.06399  296 CYS A CB  
4524 S  SG  . CYS A 316 ? 0.72525 0.45294 0.67487 -0.02163 -0.11301 0.05954  296 CYS A SG  
4530 N  N   . ALA A 317 ? 0.48614 0.24988 0.44183 -0.06812 -0.09800 0.08813  297 ALA A N   
4531 C  CA  . ALA A 317 ? 0.50796 0.28215 0.47092 -0.08002 -0.09461 0.09139  297 ALA A CA  
4532 C  C   . ALA A 317 ? 0.48298 0.25441 0.45142 -0.07833 -0.09789 0.07879  297 ALA A C   
4533 O  O   . ALA A 317 ? 0.52849 0.27847 0.49584 -0.07400 -0.10680 0.07198  297 ALA A O   
4534 C  CB  . ALA A 317 ? 0.56467 0.33011 0.53090 -0.09107 -0.09791 0.10320  297 ALA A CB  
4540 N  N   . GLY A 318 ? 0.48685 0.27919 0.46019 -0.08135 -0.09105 0.07566  298 GLY A N   
4541 C  CA  . GLY A 318 ? 0.46962 0.26123 0.44714 -0.08058 -0.09416 0.06469  298 GLY A CA  
4542 C  C   . GLY A 318 ? 0.46300 0.26014 0.43519 -0.06744 -0.09105 0.05125  298 GLY A C   
4543 O  O   . GLY A 318 ? 0.44858 0.24908 0.42250 -0.06670 -0.09190 0.04275  298 GLY A O   
4547 N  N   . GLU A 319 ? 0.45694 0.25513 0.42312 -0.05733 -0.08789 0.04943  299 GLU A N   
4548 C  CA  . GLU A 319 ? 0.41665 0.22348 0.37968 -0.04588 -0.08330 0.03811  299 GLU A CA  
4549 C  C   . GLU A 319 ? 0.39213 0.22471 0.35678 -0.04686 -0.07310 0.03910  299 GLU A C   
4550 O  O   . GLU A 319 ? 0.40717 0.25079 0.37346 -0.05364 -0.06890 0.04833  299 GLU A O   
4551 C  CB  . GLU A 319 ? 0.45593 0.25435 0.41472 -0.03436 -0.08458 0.03500  299 GLU A CB  
4552 C  CG  . GLU A 319 ? 0.42421 0.23447 0.38205 -0.03233 -0.07966 0.04153  299 GLU A CG  
4553 C  CD  . GLU A 319 ? 0.51053 0.31505 0.46704 -0.02010 -0.08143 0.03705  299 GLU A CD  
4554 O  OE1 . GLU A 319 ? 0.48676 0.29381 0.44390 -0.01115 -0.07919 0.02695  299 GLU A OE1 
4555 O  OE2 . GLU A 319 ? 0.46367 0.26143 0.41874 -0.01927 -0.08511 0.04405  299 GLU A OE2 
4562 N  N   . LYS A 320 ? 0.39157 0.23287 0.35485 -0.03961 -0.06898 0.02952  300 LYS A N   
4563 C  CA  . LYS A 320 ? 0.34194 0.20534 0.30634 -0.03923 -0.05995 0.02926  300 LYS A CA  
4564 C  C   . LYS A 320 ? 0.37805 0.24789 0.33980 -0.03024 -0.05533 0.02698  300 LYS A C   
4565 O  O   . LYS A 320 ? 0.45501 0.31557 0.41505 -0.02184 -0.05774 0.02151  300 LYS A O   
4566 C  CB  . LYS A 320 ? 0.39299 0.26243 0.35800 -0.03833 -0.05859 0.02162  300 LYS A CB  
4567 C  CG  . LYS A 320 ? 0.40972 0.28333 0.38079 -0.04897 -0.06072 0.02601  300 LYS A CG  
4568 C  CD  . LYS A 320 ? 0.42806 0.30652 0.39919 -0.04754 -0.06108 0.01838  300 LYS A CD  
4569 C  CE  . LYS A 320 ? 0.38508 0.26890 0.36493 -0.05818 -0.06433 0.02280  300 LYS A CE  
4570 N  NZ  . LYS A 320 ? 0.37216 0.26030 0.35220 -0.05703 -0.06652 0.01561  300 LYS A NZ  
4584 N  N   . MET A 321 ? 0.34116 0.22678 0.30314 -0.03207 -0.04905 0.03131  301 MET A N   
4585 C  CA  . MET A 321 ? 0.31590 0.21012 0.27669 -0.02522 -0.04492 0.02948  301 MET A CA  
4586 C  C   . MET A 321 ? 0.33352 0.24417 0.29522 -0.02449 -0.03767 0.02580  301 MET A C   
4587 O  O   . MET A 321 ? 0.32473 0.24425 0.28705 -0.03053 -0.03459 0.02914  301 MET A O   
4588 C  CB  . MET A 321 ? 0.33296 0.22838 0.29098 -0.02752 -0.04551 0.03775  301 MET A CB  
4589 C  CG  . MET A 321 ? 0.33347 0.23510 0.29115 -0.02031 -0.04407 0.03560  301 MET A CG  
4590 S  SD  . MET A 321 ? 0.36882 0.27387 0.32011 -0.02313 -0.04481 0.04457  301 MET A SD  
4591 C  CE  . MET A 321 ? 0.34783 0.26913 0.29609 -0.02901 -0.03661 0.04621  301 MET A CE  
4601 N  N   . MET A 322 ? 0.27936 0.19435 0.24185 -0.01699 -0.03472 0.01946  302 MET A N   
4602 C  CA  . MET A 322 ? 0.26406 0.19307 0.22714 -0.01629 -0.02821 0.01684  302 MET A CA  
4603 C  C   . MET A 322 ? 0.30549 0.24415 0.26793 -0.01694 -0.02530 0.02047  302 MET A C   
4604 O  O   . MET A 322 ? 0.30301 0.23861 0.26519 -0.01488 -0.02807 0.02276  302 MET A O   
4605 C  CB  . MET A 322 ? 0.30992 0.24143 0.27399 -0.00931 -0.02496 0.00966  302 MET A CB  
4606 C  CG  . MET A 322 ? 0.38955 0.31222 0.35121 -0.00726 -0.02714 0.00458  302 MET A CG  
4607 S  SD  . MET A 322 ? 0.36461 0.29256 0.32568 0.00158  -0.02108 -0.00243 302 MET A SD  
4608 C  CE  . MET A 322 ? 0.39107 0.31374 0.34551 0.00092  -0.02250 -0.00703 302 MET A CE  
4618 N  N   . LEU A 323 ? 0.25590 0.20535 0.21743 -0.01968 -0.02052 0.02098  303 LEU A N   
4619 C  CA  . LEU A 323 ? 0.27323 0.23134 0.23297 -0.01879 -0.01746 0.02175  303 LEU A CA  
4620 C  C   . LEU A 323 ? 0.27834 0.24206 0.24126 -0.01413 -0.01391 0.01590  303 LEU A C   
4621 O  O   . LEU A 323 ? 0.26365 0.23131 0.22706 -0.01429 -0.01059 0.01329  303 LEU A O   
4622 C  CB  . LEU A 323 ? 0.27039 0.23633 0.22682 -0.02354 -0.01388 0.02535  303 LEU A CB  
4623 C  CG  . LEU A 323 ? 0.26136 0.22426 0.21580 -0.02948 -0.01553 0.03236  303 LEU A CG  
4624 C  CD1 . LEU A 323 ? 0.30000 0.27401 0.25320 -0.03293 -0.01008 0.03503  303 LEU A CD1 
4625 C  CD2 . LEU A 323 ? 0.29043 0.24670 0.23974 -0.02930 -0.01939 0.03705  303 LEU A CD2 
4637 N  N   . LEU A 324 ? 0.25268 0.21692 0.21854 -0.01018 -0.01490 0.01437  304 LEU A N   
4638 C  CA  . LEU A 324 ? 0.23873 0.20816 0.20936 -0.00637 -0.01134 0.00994  304 LEU A CA  
4639 C  C   . LEU A 324 ? 0.23826 0.21510 0.20784 -0.00772 -0.00890 0.00975  304 LEU A C   
4640 O  O   . LEU A 324 ? 0.24722 0.22593 0.21847 -0.00711 -0.01109 0.01013  304 LEU A O   
4641 C  CB  . LEU A 324 ? 0.26731 0.23494 0.24466 -0.00145 -0.01336 0.00848  304 LEU A CB  
4642 C  CG  . LEU A 324 ? 0.24294 0.20171 0.22081 0.00170  -0.01572 0.00731  304 LEU A CG  
4643 C  CD1 . LEU A 324 ? 0.27798 0.23761 0.26417 0.00748  -0.01741 0.00628  304 LEU A CD1 
4644 C  CD2 . LEU A 324 ? 0.28949 0.24727 0.26521 0.00330  -0.01182 0.00338  304 LEU A CD2 
4656 N  N   . PHE A 325 ? 0.23350 0.21396 0.20024 -0.00931 -0.00507 0.00884  305 PHE A N   
4657 C  CA  . PHE A 325 ? 0.22635 0.21190 0.19050 -0.01018 -0.00314 0.00833  305 PHE A CA  
4658 C  C   . PHE A 325 ? 0.22002 0.20783 0.18952 -0.00802 -0.00235 0.00562  305 PHE A C   
4659 O  O   . PHE A 325 ? 0.24136 0.23050 0.20951 -0.00863 -0.00395 0.00516  305 PHE A O   
4660 C  CB  . PHE A 325 ? 0.24995 0.23903 0.21126 -0.01130 0.00066  0.00785  305 PHE A CB  
4661 C  CG  . PHE A 325 ? 0.24512 0.23455 0.20350 -0.01455 0.00022  0.01129  305 PHE A CG  
4662 C  CD1 . PHE A 325 ? 0.23352 0.22354 0.18695 -0.01684 -0.00077 0.01498  305 PHE A CD1 
4663 C  CD2 . PHE A 325 ? 0.25306 0.24247 0.21355 -0.01564 0.00065  0.01123  305 PHE A CD2 
4664 C  CE1 . PHE A 325 ? 0.25867 0.25002 0.21087 -0.02067 -0.00034 0.01941  305 PHE A CE1 
4665 C  CE2 . PHE A 325 ? 0.25970 0.25035 0.22015 -0.01982 -0.00016 0.01509  305 PHE A CE2 
4666 C  CZ  . PHE A 325 ? 0.25627 0.24819 0.21329 -0.02251 -0.00019 0.01953  305 PHE A CZ  
4676 N  N   . GLU A 326 ? 0.22348 0.21167 0.19855 -0.00571 0.00019  0.00391  306 GLU A N   
4677 C  CA  . GLU A 326 ? 0.24776 0.23911 0.23004 -0.00457 0.00141  0.00264  306 GLU A CA  
4678 C  C   . GLU A 326 ? 0.24196 0.23424 0.23060 -0.00415 -0.00331 0.00342  306 GLU A C   
4679 O  O   . GLU A 326 ? 0.22872 0.22349 0.22149 -0.00532 -0.00538 0.00292  306 GLU A O   
4680 C  CB  . GLU A 326 ? 0.24109 0.23350 0.22746 -0.00191 0.00617  0.00165  306 GLU A CB  
4681 C  CG  . GLU A 326 ? 0.24965 0.24638 0.24435 -0.00201 0.00868  0.00163  306 GLU A CG  
4682 C  CD  . GLU A 326 ? 0.30042 0.29889 0.29804 0.00073  0.01463  0.00174  306 GLU A CD  
4683 O  OE1 . GLU A 326 ? 0.27725 0.27246 0.26735 0.00280  0.01676  0.00090  306 GLU A OE1 
4684 O  OE2 . GLU A 326 ? 0.31883 0.32220 0.32638 0.00083  0.01711  0.00285  306 GLU A OE2 
4691 N  N   . SER A 327 ? 0.22104 0.21069 0.21095 -0.00237 -0.00600 0.00455  307 SER A N   
4692 C  CA  . SER A 327 ? 0.24702 0.23749 0.24298 -0.00136 -0.01156 0.00568  307 SER A CA  
4693 C  C   . SER A 327 ? 0.25242 0.24186 0.24182 -0.00424 -0.01655 0.00680  307 SER A C   
4694 O  O   . SER A 327 ? 0.24553 0.23780 0.24054 -0.00443 -0.02086 0.00638  307 SER A O   
4695 C  CB  . SER A 327 ? 0.22483 0.21025 0.22120 0.00151  -0.01418 0.00690  307 SER A CB  
4696 O  OG  . SER A 327 ? 0.24448 0.23111 0.24818 0.00359  -0.01997 0.00814  307 SER A OG  
4702 N  N   . ALA A 328 ? 0.21567 0.20137 0.19312 -0.00640 -0.01632 0.00832  308 ALA A N   
4703 C  CA  . ALA A 328 ? 0.24234 0.22707 0.21045 -0.00834 -0.01965 0.00913  308 ALA A CA  
4704 C  C   . ALA A 328 ? 0.23486 0.22228 0.20345 -0.00902 -0.01908 0.00565  308 ALA A C   
4705 O  O   . ALA A 328 ? 0.24467 0.23107 0.20971 -0.00950 -0.02438 0.00482  308 ALA A O   
4706 C  CB  . ALA A 328 ? 0.26957 0.25221 0.22632 -0.01037 -0.01700 0.01169  308 ALA A CB  
4712 N  N   . ASN A 329 ? 0.23082 0.22027 0.20229 -0.00904 -0.01338 0.00360  309 ASN A N   
4713 C  CA  . ASN A 329 ? 0.22688 0.21682 0.19885 -0.00975 -0.01286 0.00053  309 ASN A CA  
4714 C  C   . ASN A 329 ? 0.22762 0.21962 0.21163 -0.01036 -0.01671 -0.00052 309 ASN A C   
4715 O  O   . ASN A 329 ? 0.23336 0.22400 0.21787 -0.01181 -0.01845 -0.00303 309 ASN A O   
4716 C  CB  . ASN A 329 ? 0.21943 0.21023 0.19197 -0.00931 -0.00631 -0.00041 309 ASN A CB  
4717 C  CG  . ASN A 329 ? 0.23163 0.22191 0.19348 -0.00909 -0.00336 -0.00025 309 ASN A CG  
4718 O  OD1 . ASN A 329 ? 0.24567 0.23530 0.19916 -0.00954 -0.00522 0.00101  309 ASN A OD1 
4719 N  ND2 . ASN A 329 ? 0.25244 0.24367 0.21474 -0.00823 0.00138  -0.00103 309 ASN A ND2 
4726 N  N   . PHE A 330 ? 0.23324 0.22860 0.22802 -0.00919 -0.01802 0.00125  310 PHE A N   
4727 C  CA  . PHE A 330 ? 0.24073 0.24083 0.25031 -0.00974 -0.02171 0.00107  310 PHE A CA  
4728 C  C   . PHE A 330 ? 0.27631 0.27684 0.28815 -0.00887 -0.03014 0.00224  310 PHE A C   
4729 O  O   . PHE A 330 ? 0.25491 0.26138 0.28202 -0.00839 -0.03355 0.00281  310 PHE A O   
4730 C  CB  . PHE A 330 ? 0.24955 0.25531 0.27187 -0.00812 -0.01525 0.00218  310 PHE A CB  
4731 C  CG  . PHE A 330 ? 0.21916 0.22485 0.24174 -0.00969 -0.00884 0.00155  310 PHE A CG  
4732 C  CD1 . PHE A 330 ? 0.24770 0.24934 0.25888 -0.00874 -0.00374 0.00116  310 PHE A CD1 
4733 C  CD2 . PHE A 330 ? 0.23795 0.24700 0.27221 -0.01255 -0.00896 0.00172  310 PHE A CD2 
4734 C  CE1 . PHE A 330 ? 0.24929 0.24979 0.25934 -0.00956 0.00127  0.00097  310 PHE A CE1 
4735 C  CE2 . PHE A 330 ? 0.25708 0.26412 0.29017 -0.01402 -0.00347 0.00196  310 PHE A CE2 
4736 C  CZ  . PHE A 330 ? 0.26870 0.27116 0.28899 -0.01210 0.00163  0.00156  310 PHE A CZ  
4746 N  N   . ASP A 331 ? 0.24675 0.24157 0.24377 -0.00875 -0.03380 0.00292  311 ASP A N   
4747 C  CA  . ASP A 331 ? 0.24143 0.23481 0.23714 -0.00756 -0.04217 0.00489  311 ASP A CA  
4748 C  C   . ASP A 331 ? 0.28891 0.28200 0.28440 -0.00940 -0.05066 0.00259  311 ASP A C   
4749 O  O   . ASP A 331 ? 0.28524 0.27317 0.26626 -0.01079 -0.05183 0.00033  311 ASP A O   
4750 C  CB  . ASP A 331 ? 0.28567 0.27256 0.26454 -0.00711 -0.04187 0.00773  311 ASP A CB  
4751 C  CG  . ASP A 331 ? 0.32588 0.30957 0.30196 -0.00546 -0.05022 0.01115  311 ASP A CG  
4752 O  OD1 . ASP A 331 ? 0.33235 0.31841 0.31609 -0.00469 -0.05830 0.01055  311 ASP A OD1 
4753 O  OD2 . ASP A 331 ? 0.28880 0.26715 0.25444 -0.00526 -0.04925 0.01490  311 ASP A OD2 
4758 N  N   . GLU A 332 ? 0.30490 0.30365 0.31667 -0.00900 -0.05699 0.00291  312 GLU A N   
4759 C  CA  . GLU A 332 ? 0.34981 0.34871 0.36432 -0.01124 -0.06682 0.00050  312 GLU A CA  
4760 C  C   . GLU A 332 ? 0.40752 0.39844 0.40232 -0.01049 -0.07543 0.00054  312 GLU A C   
4761 O  O   . GLU A 332 ? 0.42288 0.41077 0.41305 -0.01230 -0.08366 -0.00276 312 GLU A O   
4762 C  CB  . GLU A 332 ? 0.37419 0.38328 0.41362 -0.01084 -0.07189 0.00171  312 GLU A CB  
4763 C  CG  . GLU A 332 ? 0.61215 0.62476 0.65885 -0.00586 -0.07260 0.00554  312 GLU A CG  
4764 C  CD  . GLU A 332 ? 0.65935 0.67241 0.70656 -0.00314 -0.06079 0.00698  312 GLU A CD  
4765 O  OE1 . GLU A 332 ? 0.62648 0.64441 0.68227 -0.00444 -0.05257 0.00585  312 GLU A OE1 
4766 O  OE2 . GLU A 332 ? 0.45764 0.46458 0.49431 -0.00020 -0.05956 0.00917  312 GLU A OE2 
4773 N  N   . ALA A 333 ? 0.35734 0.34392 0.33941 -0.00803 -0.07398 0.00430  313 ALA A N   
4774 C  CA  . ALA A 333 ? 0.38252 0.36117 0.34286 -0.00739 -0.08034 0.00535  313 ALA A CA  
4775 C  C   . ALA A 333 ? 0.43137 0.40457 0.37269 -0.00875 -0.07660 0.00171  313 ALA A C   
4776 O  O   . ALA A 333 ? 0.44064 0.40771 0.36401 -0.00814 -0.08298 0.00056  313 ALA A O   
4777 C  CB  . ALA A 333 ? 0.44077 0.41568 0.39273 -0.00524 -0.07827 0.01144  313 ALA A CB  
4783 N  N   . VAL A 334 ? 0.34966 0.32479 0.29393 -0.00983 -0.06664 -0.00024 314 VAL A N   
4784 C  CA  . VAL A 334 ? 0.33143 0.30231 0.25960 -0.00994 -0.06160 -0.00359 314 VAL A CA  
4785 C  C   . VAL A 334 ? 0.35827 0.32903 0.29459 -0.01165 -0.06168 -0.00935 314 VAL A C   
4786 O  O   . VAL A 334 ? 0.41423 0.37883 0.33737 -0.01125 -0.06419 -0.01413 314 VAL A O   
4787 C  CB  . VAL A 334 ? 0.35652 0.32907 0.28006 -0.00946 -0.05022 -0.00046 314 VAL A CB  
4788 C  CG1 . VAL A 334 ? 0.37553 0.34614 0.28698 -0.00881 -0.04403 -0.00416 314 VAL A CG1 
4789 C  CG2 . VAL A 334 ? 0.40981 0.38037 0.32308 -0.00871 -0.05084 0.00571  314 VAL A CG2 
4799 N  N   . PHE A 335 ? 0.32875 0.30539 0.28562 -0.01329 -0.05856 -0.00883 315 PHE A N   
4800 C  CA  . PHE A 335 ? 0.32618 0.30254 0.29222 -0.01554 -0.05680 -0.01256 315 PHE A CA  
4801 C  C   . PHE A 335 ? 0.34952 0.32988 0.33472 -0.01845 -0.06502 -0.01306 315 PHE A C   
4802 O  O   . PHE A 335 ? 0.37482 0.36362 0.37779 -0.01860 -0.06348 -0.00945 315 PHE A O   
4803 C  CB  . PHE A 335 ? 0.30659 0.28694 0.28031 -0.01539 -0.04562 -0.01065 315 PHE A CB  
4804 C  CG  . PHE A 335 ? 0.27792 0.25620 0.23655 -0.01307 -0.03819 -0.00995 315 PHE A CG  
4805 C  CD1 . PHE A 335 ? 0.33355 0.30662 0.27959 -0.01202 -0.03587 -0.01370 315 PHE A CD1 
4806 C  CD2 . PHE A 335 ? 0.30091 0.28244 0.25852 -0.01178 -0.03387 -0.00554 315 PHE A CD2 
4807 C  CE1 . PHE A 335 ? 0.31693 0.29046 0.25124 -0.00973 -0.02883 -0.01266 315 PHE A CE1 
4808 C  CE2 . PHE A 335 ? 0.29704 0.27795 0.24316 -0.01058 -0.02756 -0.00435 315 PHE A CE2 
4809 C  CZ  . PHE A 335 ? 0.29537 0.27350 0.23058 -0.00954 -0.02468 -0.00767 315 PHE A CZ  
4819 N  N   . CYS A 336 ? 0.32482 0.29945 0.30733 -0.02063 -0.07359 -0.01769 316 CYS A N   
4820 C  CA  . CYS A 336 ? 0.34853 0.32770 0.35166 -0.02453 -0.08220 -0.01808 316 CYS A CA  
4821 C  C   . CYS A 336 ? 0.32649 0.31200 0.35047 -0.02768 -0.07461 -0.01605 316 CYS A C   
4822 O  O   . CYS A 336 ? 0.28931 0.26947 0.30839 -0.02847 -0.06830 -0.01771 316 CYS A O   
4823 C  CB  . CYS A 336 ? 0.35683 0.32605 0.35041 -0.02660 -0.09389 -0.02431 316 CYS A CB  
4824 S  SG  . CYS A 336 ? 0.44137 0.41580 0.46112 -0.03267 -0.10710 -0.02510 316 CYS A SG  
4830 N  N   . GLU A 337 ? 0.30055 0.29767 0.34811 -0.02922 -0.07543 -0.01223 317 GLU A N   
4831 C  CA  . GLU A 337 ? 0.29285 0.29798 0.36104 -0.03200 -0.06742 -0.00906 317 GLU A CA  
4832 C  C   . GLU A 337 ? 0.29016 0.29284 0.34847 -0.02943 -0.05411 -0.00768 317 GLU A C   
4833 O  O   . GLU A 337 ? 0.28354 0.28118 0.34032 -0.03167 -0.04979 -0.00851 317 GLU A O   
4834 C  CB  . GLU A 337 ? 0.32487 0.32725 0.40479 -0.03853 -0.07309 -0.01100 317 GLU A CB  
4835 C  CG  . GLU A 337 ? 0.38633 0.39440 0.48280 -0.04203 -0.08624 -0.01148 317 GLU A CG  
4836 C  CD  . GLU A 337 ? 0.52287 0.53355 0.64128 -0.04975 -0.08880 -0.01061 317 GLU A CD  
4837 O  OE1 . GLU A 337 ? 0.40811 0.40575 0.51638 -0.05274 -0.09025 -0.01425 317 GLU A OE1 
4838 O  OE2 . GLU A 337 ? 0.64914 0.67445 0.79476 -0.05268 -0.08978 -0.00631 317 GLU A OE2 
4845 N  N   . PRO A 338 ? 0.26223 0.26744 0.31326 -0.02463 -0.04853 -0.00558 318 PRO A N   
4846 C  CA  . PRO A 338 ? 0.27146 0.27324 0.31075 -0.02223 -0.03805 -0.00501 318 PRO A CA  
4847 C  C   . PRO A 338 ? 0.25878 0.26526 0.31009 -0.02339 -0.02904 -0.00234 318 PRO A C   
4848 O  O   . PRO A 338 ? 0.27390 0.27582 0.31517 -0.02222 -0.02209 -0.00247 318 PRO A O   
4849 C  CB  . PRO A 338 ? 0.30150 0.30524 0.33407 -0.01779 -0.03622 -0.00303 318 PRO A CB  
4850 C  CG  . PRO A 338 ? 0.32324 0.33396 0.37006 -0.01732 -0.04330 -0.00145 318 PRO A CG  
4851 C  CD  . PRO A 338 ? 0.27257 0.28223 0.32495 -0.02134 -0.05299 -0.00383 318 PRO A CD  
4859 N  N   . GLU A 339 ? 0.24945 0.26570 0.32192 -0.02529 -0.02847 0.00059  319 GLU A N   
4860 C  CA  . GLU A 339 ? 0.27891 0.29961 0.36152 -0.02659 -0.01894 0.00399  319 GLU A CA  
4861 C  C   . GLU A 339 ? 0.30688 0.32236 0.39395 -0.03239 -0.02052 0.00387  319 GLU A C   
4862 O  O   . GLU A 339 ? 0.29110 0.30991 0.38776 -0.03454 -0.01320 0.00783  319 GLU A O   
4863 C  CB  . GLU A 339 ? 0.31465 0.34964 0.41849 -0.02550 -0.01560 0.00788  319 GLU A CB  
4864 C  CG  . GLU A 339 ? 0.32335 0.36141 0.42181 -0.01872 -0.01163 0.00812  319 GLU A CG  
4865 C  CD  . GLU A 339 ? 0.41228 0.44801 0.50053 -0.01529 -0.00067 0.00914  319 GLU A CD  
4866 O  OE1 . GLU A 339 ? 0.38720 0.41992 0.47279 -0.01777 0.00478  0.01046  319 GLU A OE1 
4867 O  OE2 . GLU A 339 ? 0.38001 0.41600 0.46250 -0.00992 0.00170  0.00862  319 GLU A OE2 
4874 N  N   . LYS A 340 ? 0.26632 0.27261 0.34569 -0.03484 -0.02995 -0.00046 320 LYS A N   
4875 C  CA  . LYS A 340 ? 0.27901 0.27580 0.35799 -0.03954 -0.03231 -0.00185 320 LYS A CA  
4876 C  C   . LYS A 340 ? 0.28154 0.26681 0.33839 -0.03586 -0.02818 -0.00469 320 LYS A C   
4877 O  O   . LYS A 340 ? 0.32259 0.30327 0.36252 -0.03194 -0.03083 -0.00861 320 LYS A O   
4878 C  CB  . LYS A 340 ? 0.27985 0.27170 0.36216 -0.04368 -0.04570 -0.00601 320 LYS A CB  
4879 C  CG  . LYS A 340 ? 0.46080 0.44234 0.54718 -0.04961 -0.04984 -0.00738 320 LYS A CG  
4880 C  CD  . LYS A 340 ? 0.60026 0.57383 0.68365 -0.05237 -0.06490 -0.01359 320 LYS A CD  
4881 C  CE  . LYS A 340 ? 0.72617 0.68516 0.80945 -0.05760 -0.07079 -0.01673 320 LYS A CE  
4882 N  NZ  . LYS A 340 ? 0.54633 0.48878 0.60248 -0.05272 -0.07432 -0.02449 320 LYS A NZ  
4896 N  N   . PHE A 341 ? 0.28896 0.27031 0.34626 -0.03687 -0.02144 -0.00214 321 PHE A N   
4897 C  CA  . PHE A 341 ? 0.29084 0.26131 0.32969 -0.03334 -0.01874 -0.00492 321 PHE A CA  
4898 C  C   . PHE A 341 ? 0.28699 0.24405 0.32028 -0.03563 -0.02718 -0.01009 321 PHE A C   
4899 O  O   . PHE A 341 ? 0.31606 0.26865 0.36105 -0.04124 -0.03037 -0.00872 321 PHE A O   
4900 C  CB  . PHE A 341 ? 0.29044 0.26103 0.33054 -0.03268 -0.00901 0.00006  321 PHE A CB  
4901 C  CG  . PHE A 341 ? 0.28349 0.24526 0.30648 -0.02807 -0.00600 -0.00212 321 PHE A CG  
4902 C  CD1 . PHE A 341 ? 0.25798 0.22390 0.27045 -0.02276 -0.00108 -0.00230 321 PHE A CD1 
4903 C  CD2 . PHE A 341 ? 0.32390 0.27289 0.34241 -0.02898 -0.00862 -0.00399 321 PHE A CD2 
4904 C  CE1 . PHE A 341 ? 0.27801 0.23774 0.27726 -0.01852 0.00121  -0.00412 321 PHE A CE1 
4905 C  CE2 . PHE A 341 ? 0.32080 0.26266 0.32475 -0.02361 -0.00593 -0.00607 321 PHE A CE2 
4906 C  CZ  . PHE A 341 ? 0.29354 0.24205 0.28887 -0.01849 -0.00085 -0.00589 321 PHE A CZ  
4916 N  N   . ASP A 342 ? 0.29865 0.24908 0.31430 -0.03142 -0.03105 -0.01604 322 ASP A N   
4917 C  CA  . ASP A 342 ? 0.29729 0.23404 0.30430 -0.03206 -0.03984 -0.02260 322 ASP A CA  
4918 C  C   . ASP A 342 ? 0.30493 0.23355 0.29123 -0.02525 -0.03688 -0.02720 322 ASP A C   
4919 O  O   . ASP A 342 ? 0.30759 0.23916 0.28083 -0.02084 -0.03675 -0.02980 322 ASP A O   
4920 C  CB  . ASP A 342 ? 0.32601 0.26415 0.33270 -0.03361 -0.05005 -0.02621 322 ASP A CB  
4921 C  CG  . ASP A 342 ? 0.40656 0.32983 0.40490 -0.03483 -0.06084 -0.03358 322 ASP A CG  
4922 O  OD1 . ASP A 342 ? 0.34734 0.25785 0.33629 -0.03287 -0.06031 -0.03723 322 ASP A OD1 
4923 O  OD2 . ASP A 342 ? 0.39868 0.32229 0.39968 -0.03747 -0.07100 -0.03615 322 ASP A OD2 
4928 N  N   . VAL A 343 ? 0.31687 0.23505 0.30074 -0.02441 -0.03505 -0.02803 323 VAL A N   
4929 C  CA  . VAL A 343 ? 0.32187 0.23391 0.28869 -0.01705 -0.03147 -0.03204 323 VAL A CA  
4930 C  C   . VAL A 343 ? 0.34534 0.24976 0.29587 -0.01321 -0.03798 -0.04033 323 VAL A C   
4931 O  O   . VAL A 343 ? 0.36727 0.27087 0.30310 -0.00622 -0.03406 -0.04364 323 VAL A O   
4932 C  CB  . VAL A 343 ? 0.33583 0.23671 0.30354 -0.01621 -0.02936 -0.03134 323 VAL A CB  
4933 C  CG1 . VAL A 343 ? 0.33801 0.24685 0.31780 -0.01879 -0.02164 -0.02262 323 VAL A CG1 
4934 C  CG2 . VAL A 343 ? 0.34641 0.23162 0.31741 -0.02046 -0.03844 -0.03506 323 VAL A CG2 
4944 N  N   . GLN A 344 ? 0.31474 0.21391 0.26735 -0.01743 -0.04804 -0.04382 324 GLN A N   
4945 C  CA  . GLN A 344 ? 0.33490 0.22487 0.26976 -0.01369 -0.05535 -0.05224 324 GLN A CA  
4946 C  C   . GLN A 344 ? 0.34412 0.24425 0.27100 -0.01209 -0.05604 -0.05183 324 GLN A C   
4947 O  O   . GLN A 344 ? 0.36434 0.25797 0.27329 -0.00821 -0.06114 -0.05821 324 GLN A O   
4948 C  CB  . GLN A 344 ? 0.35734 0.23377 0.29687 -0.01909 -0.06791 -0.05703 324 GLN A CB  
4949 C  CG  . GLN A 344 ? 0.37426 0.23739 0.32061 -0.02125 -0.06871 -0.05745 324 GLN A CG  
4950 C  CD  . GLN A 344 ? 0.37293 0.22241 0.32632 -0.02810 -0.08205 -0.06161 324 GLN A CD  
4951 O  OE1 . GLN A 344 ? 0.40106 0.25641 0.37607 -0.03705 -0.08524 -0.05589 324 GLN A OE1 
4952 N  NE2 . GLN A 344 ? 0.43189 0.26360 0.36817 -0.02404 -0.08987 -0.07147 324 GLN A NE2 
4961 N  N   . ARG A 345 ? 0.35449 0.26915 0.29219 -0.01416 -0.05057 -0.04456 325 ARG A N   
4962 C  CA  . ARG A 345 ? 0.32862 0.25200 0.26069 -0.01325 -0.05168 -0.04289 325 ARG A CA  
4963 C  C   . ARG A 345 ? 0.38381 0.30462 0.29262 -0.00647 -0.04938 -0.04688 325 ARG A C   
4964 O  O   . ARG A 345 ? 0.38132 0.30433 0.28348 -0.00177 -0.04048 -0.04646 325 ARG A O   
4965 C  CB  . ARG A 345 ? 0.35349 0.29088 0.29855 -0.01463 -0.04362 -0.03485 325 ARG A CB  
4966 C  CG  . ARG A 345 ? 0.36566 0.31142 0.31235 -0.01551 -0.04621 -0.03162 325 ARG A CG  
4967 C  CD  . ARG A 345 ? 0.32865 0.28586 0.28934 -0.01668 -0.03913 -0.02471 325 ARG A CD  
4968 N  NE  . ARG A 345 ? 0.27647 0.23816 0.25810 -0.02133 -0.04072 -0.02172 325 ARG A NE  
4969 C  CZ  . ARG A 345 ? 0.29658 0.26323 0.28936 -0.02404 -0.04745 -0.02037 325 ARG A CZ  
4970 N  NH1 . ARG A 345 ? 0.30160 0.26705 0.28515 -0.02280 -0.05486 -0.02215 325 ARG A NH1 
4971 N  NH2 . ARG A 345 ? 0.28956 0.26308 0.30329 -0.02776 -0.04655 -0.01678 325 ARG A NH2 
4985 N  N   . ASN A 346 ? 0.38482 0.30182 0.28165 -0.00586 -0.05739 -0.05037 326 ASN A N   
4986 C  CA  . ASN A 346 ? 0.43877 0.35375 0.31195 0.00048  -0.05524 -0.05360 326 ASN A CA  
4987 C  C   . ASN A 346 ? 0.50930 0.42629 0.37543 -0.00084 -0.06283 -0.05227 326 ASN A C   
4988 O  O   . ASN A 346 ? 0.48209 0.39245 0.35010 -0.00396 -0.07483 -0.05574 326 ASN A O   
4989 C  CB  . ASN A 346 ? 0.54494 0.44530 0.40249 0.00515  -0.05857 -0.06296 326 ASN A CB  
4990 C  CG  . ASN A 346 ? 0.69585 0.59403 0.52725 0.01222  -0.05676 -0.06688 326 ASN A CG  
4991 O  OD1 . ASN A 346 ? 0.70325 0.61210 0.52922 0.01362  -0.05035 -0.06133 326 ASN A OD1 
4992 N  ND2 . ASN A 346 ? 0.75091 0.63466 0.56522 0.01681  -0.06233 -0.07636 326 ASN A ND2 
4999 N  N   . PRO A 347 ? 0.48964 0.41514 0.34777 0.00123  -0.05707 -0.04701 327 PRO A N   
5000 C  CA  . PRO A 347 ? 0.48178 0.41633 0.33917 0.00392  -0.04409 -0.04226 327 PRO A CA  
5001 C  C   . PRO A 347 ? 0.38503 0.32830 0.26516 -0.00013 -0.03914 -0.03619 327 PRO A C   
5002 O  O   . PRO A 347 ? 0.39365 0.33842 0.28986 -0.00474 -0.04429 -0.03417 327 PRO A O   
5003 C  CB  . PRO A 347 ? 0.51876 0.45771 0.36134 0.00552  -0.04302 -0.03798 327 PRO A CB  
5004 C  CG  . PRO A 347 ? 0.53276 0.46971 0.37998 0.00174  -0.05433 -0.03669 327 PRO A CG  
5005 C  CD  . PRO A 347 ? 0.53712 0.46381 0.38781 0.00029  -0.06443 -0.04452 327 PRO A CD  
5013 N  N   . ASN A 348 ? 0.34652 0.29648 0.22822 0.00189  -0.02879 -0.03310 328 ASN A N   
5014 C  CA  . ASN A 348 ? 0.31609 0.27353 0.21576 -0.00111 -0.02399 -0.02772 328 ASN A CA  
5015 C  C   . ASN A 348 ? 0.34774 0.31397 0.24419 0.00033  -0.01570 -0.02265 328 ASN A C   
5016 O  O   . ASN A 348 ? 0.33317 0.30353 0.23377 0.00183  -0.00871 -0.02170 328 ASN A O   
5017 C  CB  . ASN A 348 ? 0.30661 0.26080 0.21606 -0.00116 -0.02161 -0.02991 328 ASN A CB  
5018 C  CG  . ASN A 348 ? 0.32426 0.28463 0.25156 -0.00472 -0.01870 -0.02466 328 ASN A CG  
5019 O  OD1 . ASN A 348 ? 0.34404 0.31144 0.27591 -0.00621 -0.01735 -0.01994 328 ASN A OD1 
5020 N  ND2 . ASN A 348 ? 0.31137 0.26833 0.24782 -0.00574 -0.01761 -0.02530 328 ASN A ND2 
5027 N  N   . SER A 349 ? 0.32727 0.29622 0.21731 -0.00054 -0.01720 -0.01883 329 SER A N   
5028 C  CA  . SER A 349 ? 0.32601 0.30247 0.21286 -0.00027 -0.01020 -0.01330 329 SER A CA  
5029 C  C   . SER A 349 ? 0.31252 0.29404 0.21459 -0.00369 -0.00857 -0.00799 329 SER A C   
5030 O  O   . SER A 349 ? 0.31243 0.29567 0.21463 -0.00569 -0.00976 -0.00295 329 SER A O   
5031 C  CB  . SER A 349 ? 0.39796 0.37329 0.26914 0.00027  -0.01249 -0.01089 329 SER A CB  
5032 O  OG  . SER A 349 ? 0.46298 0.43304 0.31708 0.00445  -0.01352 -0.01653 329 SER A OG  
5038 N  N   . HIS A 350 ? 0.28034 0.26311 0.19419 -0.00393 -0.00594 -0.00923 330 HIS A N   
5039 C  CA  . HIS A 350 ? 0.25226 0.23850 0.17889 -0.00623 -0.00452 -0.00553 330 HIS A CA  
5040 C  C   . HIS A 350 ? 0.26834 0.26029 0.19418 -0.00673 0.00078  -0.00125 330 HIS A C   
5041 O  O   . HIS A 350 ? 0.27143 0.26684 0.18955 -0.00531 0.00486  -0.00083 330 HIS A O   
5042 C  CB  . HIS A 350 ? 0.27115 0.25669 0.20809 -0.00605 -0.00281 -0.00761 330 HIS A CB  
5043 C  CG  . HIS A 350 ? 0.27122 0.25793 0.20532 -0.00346 0.00226  -0.00937 330 HIS A CG  
5044 N  ND1 . HIS A 350 ? 0.25072 0.24325 0.18679 -0.00306 0.00711  -0.00665 330 HIS A ND1 
5045 C  CD2 . HIS A 350 ? 0.29798 0.28070 0.22702 -0.00068 0.00261  -0.01369 330 HIS A CD2 
5046 C  CE1 . HIS A 350 ? 0.28117 0.27470 0.21457 0.00014  0.01048  -0.00893 330 HIS A CE1 
5047 N  NE2 . HIS A 350 ? 0.28630 0.27333 0.21510 0.00199  0.00808  -0.01331 330 HIS A NE2 
5055 N  N   . LEU A 351 ? 0.26179 0.25474 0.19609 -0.00877 0.00037  0.00193  331 LEU A N   
5056 C  CA  . LEU A 351 ? 0.27103 0.26769 0.20676 -0.01045 0.00336  0.00610  331 LEU A CA  
5057 C  C   . LEU A 351 ? 0.25206 0.25090 0.19605 -0.01021 0.00623  0.00538  331 LEU A C   
5058 O  O   . LEU A 351 ? 0.25669 0.25646 0.20426 -0.01208 0.00645  0.00815  331 LEU A O   
5059 C  CB  . LEU A 351 ? 0.25437 0.24786 0.19115 -0.01265 -0.00066 0.01010  331 LEU A CB  
5060 C  CG  . LEU A 351 ? 0.27946 0.27009 0.20687 -0.01280 -0.00448 0.01179  331 LEU A CG  
5061 C  CD1 . LEU A 351 ? 0.29679 0.28336 0.22459 -0.01468 -0.00871 0.01690  331 LEU A CD1 
5062 C  CD2 . LEU A 351 ? 0.34387 0.33763 0.25942 -0.01230 -0.00076 0.01270  331 LEU A CD2 
5074 N  N   . ALA A 352 ? 0.23647 0.23527 0.18255 -0.00795 0.00800  0.00185  332 ALA A N   
5075 C  CA  . ALA A 352 ? 0.23764 0.23792 0.18937 -0.00727 0.01028  0.00159  332 ALA A CA  
5076 C  C   . ALA A 352 ? 0.22221 0.22841 0.17409 -0.00788 0.01277  0.00366  332 ALA A C   
5077 O  O   . ALA A 352 ? 0.24178 0.24870 0.19805 -0.00852 0.01263  0.00444  332 ALA A O   
5078 C  CB  . ALA A 352 ? 0.24172 0.24013 0.19435 -0.00468 0.01170  -0.00155 332 ALA A CB  
5084 N  N   . PHE A 353 ? 0.22763 0.23849 0.17487 -0.00750 0.01501  0.00445  333 PHE A N   
5085 C  CA  . PHE A 353 ? 0.24580 0.26513 0.19549 -0.00847 0.01806  0.00725  333 PHE A CA  
5086 C  C   . PHE A 353 ? 0.25888 0.27996 0.20757 -0.01289 0.01753  0.01243  333 PHE A C   
5087 O  O   . PHE A 353 ? 0.25318 0.28253 0.20413 -0.01466 0.02063  0.01595  333 PHE A O   
5088 C  CB  . PHE A 353 ? 0.24318 0.26832 0.18927 -0.00456 0.02235  0.00540  333 PHE A CB  
5089 C  CG  . PHE A 353 ? 0.24503 0.26822 0.19271 -0.00007 0.02285  0.00111  333 PHE A CG  
5090 C  CD1 . PHE A 353 ? 0.24120 0.26689 0.19622 0.00047  0.02253  0.00141  333 PHE A CD1 
5091 C  CD2 . PHE A 353 ? 0.25956 0.27757 0.20060 0.00379  0.02307  -0.00316 333 PHE A CD2 
5092 C  CE1 . PHE A 353 ? 0.26625 0.28942 0.22193 0.00488  0.02281  -0.00160 333 PHE A CE1 
5093 C  CE2 . PHE A 353 ? 0.26723 0.28172 0.20976 0.00784  0.02318  -0.00656 333 PHE A CE2 
5094 C  CZ  . PHE A 353 ? 0.23503 0.25220 0.18479 0.00848  0.02332  -0.00536 333 PHE A CZ  
5104 N  N   . GLY A 354 ? 0.23958 0.25333 0.18544 -0.01465 0.01370  0.01350  334 GLY A N   
5105 C  CA  . GLY A 354 ? 0.25187 0.26493 0.19507 -0.01851 0.01258  0.01894  334 GLY A CA  
5106 C  C   . GLY A 354 ? 0.27216 0.28861 0.20539 -0.01780 0.01559  0.02092  334 GLY A C   
5107 O  O   . GLY A 354 ? 0.27968 0.29545 0.20608 -0.01387 0.01648  0.01682  334 GLY A O   
5111 N  N   . PHE A 355 ? 0.27909 0.29873 0.21080 -0.02171 0.01721  0.02746  335 PHE A N   
5112 C  CA  . PHE A 355 ? 0.30547 0.32737 0.22529 -0.02144 0.02024  0.03096  335 PHE A CA  
5113 C  C   . PHE A 355 ? 0.32732 0.35503 0.24980 -0.02698 0.02347  0.03959  335 PHE A C   
5114 O  O   . PHE A 355 ? 0.33701 0.36044 0.26705 -0.03188 0.01967  0.04341  335 PHE A O   
5115 C  CB  . PHE A 355 ? 0.31382 0.32538 0.22371 -0.02067 0.01441  0.03084  335 PHE A CB  
5116 C  CG  . PHE A 355 ? 0.35596 0.36826 0.25062 -0.01992 0.01666  0.03434  335 PHE A CG  
5117 C  CD1 . PHE A 355 ? 0.44389 0.45782 0.32780 -0.01469 0.01916  0.02905  335 PHE A CD1 
5118 C  CD2 . PHE A 355 ? 0.38267 0.39280 0.27199 -0.02405 0.01615  0.04284  335 PHE A CD2 
5119 C  CE1 . PHE A 355 ? 0.50936 0.52328 0.37617 -0.01304 0.02137  0.03157  335 PHE A CE1 
5120 C  CE2 . PHE A 355 ? 0.44689 0.45752 0.31933 -0.02287 0.01877  0.04654  335 PHE A CE2 
5121 C  CZ  . PHE A 355 ? 0.47690 0.48968 0.33762 -0.01711 0.02149  0.04059  335 PHE A CZ  
5131 N  N   . GLY A 356 ? 0.31720 0.35396 0.23300 -0.02615 0.03046  0.04275  336 GLY A N   
5132 C  CA  . GLY A 356 ? 0.35072 0.39390 0.26848 -0.03202 0.03451  0.05245  336 GLY A CA  
5133 C  C   . GLY A 356 ? 0.30340 0.36028 0.23697 -0.03507 0.03938  0.05503  336 GLY A C   
5134 O  O   . GLY A 356 ? 0.30493 0.37006 0.24382 -0.03051 0.04265  0.04953  336 GLY A O   
5138 N  N   . THR A 357 ? 0.29176 0.35008 0.23347 -0.04300 0.03880  0.06358  337 THR A N   
5139 C  CA  . THR A 357 ? 0.34705 0.41901 0.30579 -0.04794 0.04232  0.06793  337 THR A CA  
5140 C  C   . THR A 357 ? 0.29828 0.37356 0.26951 -0.04511 0.03935  0.06022  337 THR A C   
5141 O  O   . THR A 357 ? 0.29924 0.38985 0.28125 -0.04410 0.04431  0.06023  337 THR A O   
5142 C  CB  . THR A 357 ? 0.35351 0.41860 0.31925 -0.05776 0.03736  0.07655  337 THR A CB  
5143 O  OG1 . THR A 357 ? 0.45710 0.51850 0.41032 -0.06046 0.04014  0.08500  337 THR A OG1 
5144 C  CG2 . THR A 357 ? 0.38295 0.46006 0.36745 -0.06434 0.03872  0.08127  337 THR A CG2 
5152 N  N   . HIS A 358 ? 0.26547 0.32717 0.23545 -0.04348 0.03150  0.05405  338 HIS A N   
5153 C  CA  . HIS A 358 ? 0.25481 0.31718 0.23487 -0.04159 0.02771  0.04786  338 HIS A CA  
5154 C  C   . HIS A 358 ? 0.28033 0.34052 0.25390 -0.03312 0.02844  0.03930  338 HIS A C   
5155 O  O   . HIS A 358 ? 0.25607 0.31386 0.23497 -0.03105 0.02482  0.03431  338 HIS A O   
5156 C  CB  . HIS A 358 ? 0.27034 0.31909 0.25395 -0.04576 0.01883  0.04728  338 HIS A CB  
5157 C  CG  . HIS A 358 ? 0.25785 0.30744 0.25073 -0.05480 0.01648  0.05508  338 HIS A CG  
5158 N  ND1 . HIS A 358 ? 0.26268 0.32158 0.27068 -0.05920 0.01510  0.05662  338 HIS A ND1 
5159 C  CD2 . HIS A 358 ? 0.27063 0.31259 0.26032 -0.06059 0.01475  0.06221  338 HIS A CD2 
5160 C  CE1 . HIS A 358 ? 0.27758 0.33466 0.29211 -0.06801 0.01272  0.06438  338 HIS A CE1 
5161 N  NE2 . HIS A 358 ? 0.27147 0.31772 0.27462 -0.06895 0.01270  0.06815  338 HIS A NE2 
5169 N  N   . PHE A 359 ? 0.27082 0.33075 0.23232 -0.02838 0.03255  0.03762  339 PHE A N   
5170 C  CA  . PHE A 359 ? 0.26519 0.32188 0.22061 -0.02091 0.03287  0.02973  339 PHE A CA  
5171 C  C   . PHE A 359 ? 0.25922 0.32381 0.22493 -0.01766 0.03402  0.02616  339 PHE A C   
5172 O  O   . PHE A 359 ? 0.25604 0.33452 0.22965 -0.01763 0.03884  0.02888  339 PHE A O   
5173 C  CB  . PHE A 359 ? 0.26928 0.32856 0.21157 -0.01659 0.03836  0.02919  339 PHE A CB  
5174 C  CG  . PHE A 359 ? 0.32473 0.37973 0.26062 -0.00921 0.03833  0.02103  339 PHE A CG  
5175 C  CD1 . PHE A 359 ? 0.30591 0.34797 0.23680 -0.00825 0.03235  0.01665  339 PHE A CD1 
5176 C  CD2 . PHE A 359 ? 0.38437 0.44820 0.32003 -0.00325 0.04421  0.01801  339 PHE A CD2 
5177 C  CE1 . PHE A 359 ? 0.36943 0.40624 0.29578 -0.00270 0.03149  0.00972  339 PHE A CE1 
5178 C  CE2 . PHE A 359 ? 0.41170 0.46878 0.34129 0.00331  0.04311  0.01040  339 PHE A CE2 
5179 C  CZ  . PHE A 359 ? 0.36480 0.40808 0.29000 0.00297  0.03657  0.00654  339 PHE A CZ  
5189 N  N   . CYS A 360 ? 0.24795 0.30430 0.21366 -0.01461 0.02983  0.02052  340 CYS A N   
5190 C  CA  . CYS A 360 ? 0.22984 0.29071 0.20449 -0.01204 0.02890  0.01782  340 CYS A CA  
5191 C  C   . CYS A 360 ? 0.24082 0.31546 0.22003 -0.00762 0.03477  0.01768  340 CYS A C   
5192 O  O   . CYS A 360 ? 0.25124 0.32559 0.22269 -0.00172 0.03861  0.01426  340 CYS A O   
5193 C  CB  . CYS A 360 ? 0.23506 0.28497 0.20500 -0.00784 0.02576  0.01209  340 CYS A CB  
5194 S  SG  . CYS A 360 ? 0.23137 0.28453 0.20886 -0.00392 0.02419  0.00941  340 CYS A SG  
5199 N  N   . LEU A 361 ? 0.23272 0.31903 0.22536 -0.00981 0.03468  0.02066  341 LEU A N   
5200 C  CA  . LEU A 361 ? 0.22995 0.33194 0.23013 -0.00511 0.04041  0.02093  341 LEU A CA  
5201 C  C   . LEU A 361 ? 0.23449 0.33329 0.23299 0.00335  0.03965  0.01469  341 LEU A C   
5202 O  O   . LEU A 361 ? 0.26000 0.36674 0.25865 0.01010  0.04508  0.01277  341 LEU A O   
5203 C  CB  . LEU A 361 ? 0.25445 0.37051 0.27210 -0.01035 0.03920  0.02608  341 LEU A CB  
5204 C  CG  . LEU A 361 ? 0.30442 0.44125 0.33461 -0.00627 0.04565  0.02789  341 LEU A CG  
5205 C  CD1 . LEU A 361 ? 0.35319 0.49787 0.37688 -0.00459 0.05542  0.03063  341 LEU A CD1 
5206 C  CD2 . LEU A 361 ? 0.32694 0.47610 0.37633 -0.01335 0.04197  0.03320  341 LEU A CD2 
5218 N  N   . GLY A 362 ? 0.22426 0.31067 0.21996 0.00350  0.03345  0.01165  342 GLY A N   
5219 C  CA  . GLY A 362 ? 0.24008 0.32029 0.23332 0.01028  0.03164  0.00691  342 GLY A CA  
5220 C  C   . GLY A 362 ? 0.23880 0.30636 0.21906 0.01430  0.03288  0.00252  342 GLY A C   
5221 O  O   . GLY A 362 ? 0.25901 0.31892 0.23671 0.01906  0.03100  -0.00084 342 GLY A O   
5225 N  N   . ASN A 363 ? 0.23341 0.29755 0.20532 0.01210  0.03509  0.00276  343 ASN A N   
5226 C  CA  . ASN A 363 ? 0.25462 0.30498 0.21506 0.01436  0.03386  -0.00152 343 ASN A CA  
5227 C  C   . ASN A 363 ? 0.26411 0.31188 0.22065 0.02248  0.03583  -0.00651 343 ASN A C   
5228 O  O   . ASN A 363 ? 0.27013 0.30506 0.22149 0.02425  0.03278  -0.01002 343 ASN A O   
5229 C  CB  . ASN A 363 ? 0.25685 0.30473 0.20851 0.01121  0.03496  -0.00044 343 ASN A CB  
5230 C  CG  . ASN A 363 ? 0.29217 0.34774 0.23803 0.01546  0.04103  -0.00112 343 ASN A CG  
5231 O  OD1 . ASN A 363 ? 0.34857 0.39728 0.28424 0.02076  0.04171  -0.00627 343 ASN A OD1 
5232 N  ND2 . ASN A 363 ? 0.31353 0.38331 0.26572 0.01351  0.04562  0.00385  343 ASN A ND2 
5239 N  N   . GLN A 364 ? 0.25486 0.31403 0.21377 0.02759  0.04104  -0.00691 344 GLN A N   
5240 C  CA  . GLN A 364 ? 0.26888 0.32418 0.22359 0.03653  0.04264  -0.01238 344 GLN A CA  
5241 C  C   . GLN A 364 ? 0.28506 0.33614 0.24655 0.03970  0.03879  -0.01323 344 GLN A C   
5242 O  O   . GLN A 364 ? 0.28786 0.32637 0.24373 0.04446  0.03669  -0.01747 344 GLN A O   
5243 C  CB  . GLN A 364 ? 0.29696 0.36750 0.25382 0.04247  0.05007  -0.01252 344 GLN A CB  
5244 C  CG  . GLN A 364 ? 0.37226 0.43782 0.32367 0.05304  0.05186  -0.01905 344 GLN A CG  
5245 C  CD  . GLN A 364 ? 0.43762 0.52090 0.39375 0.06027  0.06008  -0.01905 344 GLN A CD  
5246 O  OE1 . GLN A 364 ? 0.41910 0.51930 0.38286 0.05632  0.06496  -0.01338 344 GLN A OE1 
5247 N  NE2 . GLN A 364 ? 0.41892 0.49814 0.37048 0.07096  0.06198  -0.02531 344 GLN A NE2 
5256 N  N   . LEU A 365 ? 0.25510 0.31603 0.22826 0.03731  0.03737  -0.00911 345 LEU A N   
5257 C  CA  . LEU A 365 ? 0.27368 0.33053 0.25165 0.04039  0.03306  -0.00924 345 LEU A CA  
5258 C  C   . LEU A 365 ? 0.25943 0.29936 0.23030 0.03684  0.02838  -0.00959 345 LEU A C   
5259 O  O   . LEU A 365 ? 0.26944 0.29874 0.23727 0.04101  0.02611  -0.01133 345 LEU A O   
5260 C  CB  . LEU A 365 ? 0.24886 0.31928 0.23969 0.03762  0.03111  -0.00490 345 LEU A CB  
5261 C  CG  . LEU A 365 ? 0.26779 0.33467 0.26245 0.04057  0.02562  -0.00440 345 LEU A CG  
5262 C  CD1 . LEU A 365 ? 0.28655 0.35289 0.28244 0.05066  0.02637  -0.00720 345 LEU A CD1 
5263 C  CD2 . LEU A 365 ? 0.30452 0.38482 0.31148 0.03672  0.02233  -0.00053 345 LEU A CD2 
5275 N  N   . ALA A 366 ? 0.25425 0.29137 0.22268 0.02935  0.02723  -0.00763 346 ALA A N   
5276 C  CA  . ALA A 366 ? 0.25007 0.27338 0.21310 0.02617  0.02402  -0.00771 346 ALA A CA  
5277 C  C   . ALA A 366 ? 0.25116 0.26233 0.20670 0.02888  0.02419  -0.01153 346 ALA A C   
5278 O  O   . ALA A 366 ? 0.25240 0.25244 0.20589 0.02969  0.02196  -0.01180 346 ALA A O   
5279 C  CB  . ALA A 366 ? 0.26170 0.28546 0.22424 0.01896  0.02325  -0.00550 346 ALA A CB  
5285 N  N   . ARG A 367 ? 0.26238 0.27488 0.21315 0.02984  0.02648  -0.01425 347 ARG A N   
5286 C  CA  . ARG A 367 ? 0.28073 0.28071 0.22360 0.03225  0.02528  -0.01883 347 ARG A CA  
5287 C  C   . ARG A 367 ? 0.30206 0.29572 0.24464 0.03962  0.02482  -0.02162 347 ARG A C   
5288 O  O   . ARG A 367 ? 0.29160 0.27090 0.23068 0.04002  0.02173  -0.02360 347 ARG A O   
5289 C  CB  . ARG A 367 ? 0.29266 0.29550 0.22810 0.03310  0.02756  -0.02164 347 ARG A CB  
5290 C  CG  . ARG A 367 ? 0.28149 0.28390 0.21486 0.02579  0.02582  -0.01934 347 ARG A CG  
5291 C  CD  . ARG A 367 ? 0.32303 0.33023 0.24776 0.02679  0.02851  -0.02065 347 ARG A CD  
5292 N  NE  . ARG A 367 ? 0.32049 0.32297 0.24092 0.02113  0.02505  -0.01960 347 ARG A NE  
5293 C  CZ  . ARG A 367 ? 0.37782 0.38669 0.29598 0.01759  0.02623  -0.01598 347 ARG A CZ  
5294 N  NH1 . ARG A 367 ? 0.39511 0.41631 0.31536 0.01802  0.03143  -0.01244 347 ARG A NH1 
5295 N  NH2 . ARG A 367 ? 0.35724 0.36003 0.27156 0.01344  0.02182  -0.01548 347 ARG A NH2 
5309 N  N   . LEU A 368 ? 0.26218 0.26632 0.20940 0.04553  0.02755  -0.02156 348 LEU A N   
5310 C  CA  . LEU A 368 ? 0.27667 0.27493 0.22421 0.05372  0.02673  -0.02413 348 LEU A CA  
5311 C  C   . LEU A 368 ? 0.27448 0.26334 0.22455 0.05227  0.02251  -0.02074 348 LEU A C   
5312 O  O   . LEU A 368 ? 0.29547 0.26965 0.24177 0.05555  0.01993  -0.02250 348 LEU A O   
5313 C  CB  . LEU A 368 ? 0.28375 0.29856 0.23839 0.06038  0.03072  -0.02410 348 LEU A CB  
5314 C  CG  . LEU A 368 ? 0.31214 0.32351 0.26815 0.07096  0.03045  -0.02728 348 LEU A CG  
5315 C  CD1 . LEU A 368 ? 0.33773 0.33363 0.28237 0.07604  0.03025  -0.03408 348 LEU A CD1 
5316 C  CD2 . LEU A 368 ? 0.31281 0.34473 0.27908 0.07716  0.03499  -0.02659 348 LEU A CD2 
5328 N  N   . GLU A 369 ? 0.26996 0.26599 0.22533 0.04751  0.02159  -0.01576 349 GLU A N   
5329 C  CA  . GLU A 369 ? 0.28714 0.27440 0.24222 0.04621  0.01824  -0.01215 349 GLU A CA  
5330 C  C   . GLU A 369 ? 0.29569 0.26793 0.24527 0.04149  0.01703  -0.01202 349 GLU A C   
5331 O  O   . GLU A 369 ? 0.29042 0.25004 0.23761 0.04292  0.01502  -0.01064 349 GLU A O   
5332 C  CB  . GLU A 369 ? 0.28853 0.28524 0.24776 0.04183  0.01727  -0.00793 349 GLU A CB  
5333 C  CG  . GLU A 369 ? 0.28719 0.29844 0.25432 0.04550  0.01680  -0.00706 349 GLU A CG  
5334 C  CD  . GLU A 369 ? 0.34508 0.36463 0.31606 0.04030  0.01467  -0.00385 349 GLU A CD  
5335 O  OE1 . GLU A 369 ? 0.33102 0.34446 0.29734 0.03477  0.01391  -0.00244 349 GLU A OE1 
5336 O  OE2 . GLU A 369 ? 0.33149 0.36427 0.31105 0.04194  0.01351  -0.00292 349 GLU A OE2 
5343 N  N   . LEU A 370 ? 0.27451 0.24822 0.22296 0.03559  0.01802  -0.01285 350 LEU A N   
5344 C  CA  . LEU A 370 ? 0.28918 0.25137 0.23536 0.03052  0.01659  -0.01257 350 LEU A CA  
5345 C  C   . LEU A 370 ? 0.29673 0.24521 0.23920 0.03372  0.01451  -0.01636 350 LEU A C   
5346 O  O   . LEU A 370 ? 0.29248 0.22866 0.23499 0.03138  0.01251  -0.01440 350 LEU A O   
5347 C  CB  . LEU A 370 ? 0.28921 0.25652 0.23561 0.02479  0.01713  -0.01326 350 LEU A CB  
5348 C  CG  . LEU A 370 ? 0.29447 0.27121 0.24427 0.02075  0.01825  -0.00947 350 LEU A CG  
5349 C  CD1 . LEU A 370 ? 0.32272 0.30503 0.27249 0.01666  0.01849  -0.01027 350 LEU A CD1 
5350 C  CD2 . LEU A 370 ? 0.34576 0.31675 0.29675 0.01761  0.01800  -0.00564 350 LEU A CD2 
5362 N  N   . SER A 371 ? 0.27552 0.22548 0.21449 0.03903  0.01505  -0.02176 351 SER A N   
5363 C  CA  A SER A 371 ? 0.32282 0.25808 0.25657 0.04296  0.01235  -0.02684 351 SER A CA  
5364 C  CA  B SER A 371 ? 0.32294 0.25827 0.25668 0.04297  0.01237  -0.02685 351 SER A CA  
5365 C  C   . SER A 371 ? 0.35399 0.27939 0.28854 0.04825  0.01070  -0.02540 351 SER A C   
5366 O  O   . SER A 371 ? 0.35073 0.25951 0.28363 0.04702  0.00716  -0.02551 351 SER A O   
5367 C  CB  A SER A 371 ? 0.34972 0.28949 0.27754 0.04900  0.01420  -0.03331 351 SER A CB  
5368 C  CB  B SER A 371 ? 0.34907 0.28955 0.27711 0.04909  0.01438  -0.03317 351 SER A CB  
5369 O  OG  A SER A 371 ? 0.38935 0.33853 0.31531 0.04439  0.01581  -0.03352 351 SER A OG  
5370 O  OG  B SER A 371 ? 0.38741 0.31198 0.30836 0.05333  0.01111  -0.03942 351 SER A OG  
5379 N  N   . LEU A 372 ? 0.32980 0.26490 0.26753 0.05391  0.01259  -0.02353 352 LEU A N   
5380 C  CA  . LEU A 372 ? 0.33715 0.26261 0.27497 0.06044  0.01029  -0.02235 352 LEU A CA  
5381 C  C   . LEU A 372 ? 0.34039 0.25583 0.27866 0.05513  0.00813  -0.01544 352 LEU A C   
5382 O  O   . LEU A 372 ? 0.35652 0.25543 0.29240 0.05722  0.00510  -0.01447 352 LEU A O   
5383 C  CB  . LEU A 372 ? 0.35537 0.29571 0.29817 0.06801  0.01212  -0.02187 352 LEU A CB  
5384 C  CG  . LEU A 372 ? 0.33522 0.28414 0.27765 0.07534  0.01531  -0.02844 352 LEU A CG  
5385 C  CD1 . LEU A 372 ? 0.33804 0.30637 0.28948 0.08061  0.01759  -0.02638 352 LEU A CD1 
5386 C  CD2 . LEU A 372 ? 0.40027 0.33253 0.33660 0.08360  0.01324  -0.03459 352 LEU A CD2 
5398 N  N   . MET A 373 ? 0.32204 0.24645 0.26267 0.04862  0.00982  -0.01044 353 MET A N   
5399 C  CA  . MET A 373 ? 0.32578 0.24163 0.26535 0.04424  0.00911  -0.00366 353 MET A CA  
5400 C  C   . MET A 373 ? 0.32694 0.22990 0.26647 0.03760  0.00827  -0.00324 353 MET A C   
5401 O  O   . MET A 373 ? 0.33523 0.22422 0.27361 0.03638  0.00676  0.00100  353 MET A O   
5402 C  CB  . MET A 373 ? 0.34519 0.27327 0.28588 0.03999  0.01132  0.00058  353 MET A CB  
5403 C  CG  . MET A 373 ? 0.33212 0.25266 0.26978 0.03614  0.01196  0.00770  353 MET A CG  
5404 S  SD  . MET A 373 ? 0.37610 0.28272 0.30829 0.04210  0.00909  0.01303  353 MET A SD  
5405 C  CE  . MET A 373 ? 0.40335 0.32314 0.33310 0.04643  0.00791  0.01507  353 MET A CE  
5415 N  N   . THR A 374 ? 0.33261 0.23979 0.27388 0.03313  0.00871  -0.00726 354 THR A N   
5416 C  CA  . THR A 374 ? 0.31447 0.21124 0.25803 0.02615  0.00687  -0.00685 354 THR A CA  
5417 C  C   . THR A 374 ? 0.35227 0.23080 0.29322 0.02903  0.00238  -0.01032 354 THR A C   
5418 O  O   . THR A 374 ? 0.35265 0.21801 0.29605 0.02428  0.00033  -0.00648 354 THR A O   
5419 C  CB  . THR A 374 ? 0.30302 0.20875 0.24865 0.02158  0.00707  -0.01063 354 THR A CB  
5420 O  OG1 . THR A 374 ? 0.29627 0.21646 0.24448 0.01886  0.01072  -0.00715 354 THR A OG1 
5421 C  CG2 . THR A 374 ? 0.34066 0.23732 0.29095 0.01399  0.00399  -0.01037 354 THR A CG2 
5429 N  N   . GLU A 375 ? 0.33584 0.21277 0.27192 0.03722  0.00099  -0.01716 355 GLU A N   
5430 C  CA  . GLU A 375 ? 0.37548 0.23320 0.30770 0.04171  -0.00365 -0.02130 355 GLU A CA  
5431 C  C   . GLU A 375 ? 0.37889 0.22387 0.31182 0.04275  -0.00500 -0.01448 355 GLU A C   
5432 O  O   . GLU A 375 ? 0.42317 0.24911 0.35621 0.03989  -0.00920 -0.01344 355 GLU A O   
5433 C  CB  . GLU A 375 ? 0.42753 0.28881 0.35414 0.05261  -0.00315 -0.02932 355 GLU A CB  
5434 C  CG  . GLU A 375 ? 0.54663 0.38859 0.46770 0.05978  -0.00767 -0.03536 355 GLU A CG  
5435 C  CD  . GLU A 375 ? 0.86656 0.71594 0.78208 0.07137  -0.00533 -0.04375 355 GLU A CD  
5436 O  OE1 . GLU A 375 ? 0.66047 0.52845 0.57942 0.07624  -0.00039 -0.04185 355 GLU A OE1 
5437 O  OE2 . GLU A 375 ? 1.01463 0.85135 0.92252 0.07568  -0.00845 -0.05227 355 GLU A OE2 
5444 N  N   . ARG A 376 ? 0.38377 0.23840 0.31696 0.04637  -0.00205 -0.00930 356 ARG A N   
5445 C  CA  . ARG A 376 ? 0.38941 0.23172 0.32102 0.04860  -0.00370 -0.00248 356 ARG A CA  
5446 C  C   . ARG A 376 ? 0.38945 0.22648 0.32333 0.03872  -0.00229 0.00663  356 ARG A C   
5447 O  O   . ARG A 376 ? 0.42641 0.24597 0.35911 0.03755  -0.00473 0.01178  356 ARG A O   
5448 C  CB  . ARG A 376 ? 0.40010 0.25426 0.33056 0.05639  -0.00228 -0.00034 356 ARG A CB  
5449 C  CG  . ARG A 376 ? 0.48234 0.33417 0.41159 0.06834  -0.00468 -0.00708 356 ARG A CG  
5450 C  CD  . ARG A 376 ? 0.43702 0.30898 0.36931 0.07492  -0.00258 -0.00794 356 ARG A CD  
5451 N  NE  . ARG A 376 ? 0.47609 0.34704 0.40884 0.08629  -0.00377 -0.01486 356 ARG A NE  
5452 C  CZ  . ARG A 376 ? 0.49535 0.37072 0.42749 0.08864  -0.00170 -0.02315 356 ARG A CZ  
5453 N  NH1 . ARG A 376 ? 0.48487 0.36759 0.41648 0.08054  0.00101  -0.02509 356 ARG A NH1 
5454 N  NH2 . ARG A 376 ? 0.51800 0.38971 0.44909 0.09993  -0.00240 -0.02964 356 ARG A NH2 
5468 N  N   . VAL A 377 ? 0.37586 0.22738 0.31318 0.03191  0.00184  0.00884  357 VAL A N   
5469 C  CA  . VAL A 377 ? 0.36712 0.21642 0.30788 0.02279  0.00456  0.01707  357 VAL A CA  
5470 C  C   . VAL A 377 ? 0.39545 0.23000 0.34164 0.01608  0.00112  0.01651  357 VAL A C   
5471 O  O   . VAL A 377 ? 0.39684 0.21899 0.34496 0.01133  0.00097  0.02403  357 VAL A O   
5472 C  CB  . VAL A 377 ? 0.36632 0.23452 0.31025 0.01829  0.00937  0.01766  357 VAL A CB  
5473 C  CG1 . VAL A 377 ? 0.41392 0.28156 0.36402 0.00887  0.01272  0.02459  357 VAL A CG1 
5474 C  CG2 . VAL A 377 ? 0.36696 0.24583 0.30515 0.02345  0.01192  0.02030  357 VAL A CG2 
5484 N  N   . LEU A 378 ? 0.37842 0.21325 0.32666 0.01559  -0.00227 0.00769  358 LEU A N   
5485 C  CA  . LEU A 378 ? 0.42219 0.24220 0.37544 0.00922  -0.00749 0.00578  358 LEU A CA  
5486 C  C   . LEU A 378 ? 0.44976 0.24652 0.39969 0.01209  -0.01233 0.00712  358 LEU A C   
5487 O  O   . LEU A 378 ? 0.45735 0.23985 0.41313 0.00441  -0.01533 0.01160  358 LEU A O   
5488 C  CB  . LEU A 378 ? 0.41102 0.23380 0.36280 0.01063  -0.01140 -0.00523 358 LEU A CB  
5489 C  CG  . LEU A 378 ? 0.41351 0.25475 0.37034 0.00538  -0.00869 -0.00608 358 LEU A CG  
5490 C  CD1 . LEU A 378 ? 0.40645 0.25162 0.35662 0.01043  -0.01141 -0.01660 358 LEU A CD1 
5491 C  CD2 . LEU A 378 ? 0.41303 0.25260 0.38141 -0.00578 -0.01054 -0.00213 358 LEU A CD2 
5503 N  N   . ARG A 379 ? 0.42245 0.21477 0.36411 0.02314  -0.01361 0.00321  359 ARG A N   
5504 C  CA  . ARG A 379 ? 0.47491 0.24375 0.41254 0.02795  -0.01921 0.00260  359 ARG A CA  
5505 C  C   . ARG A 379 ? 0.45843 0.21898 0.39508 0.02728  -0.01758 0.01446  359 ARG A C   
5506 O  O   . ARG A 379 ? 0.48414 0.22281 0.42124 0.02471  -0.02195 0.01847  359 ARG A O   
5507 C  CB  . ARG A 379 ? 0.50511 0.27433 0.43518 0.04136  -0.02089 -0.00696 359 ARG A CB  
5508 C  CG  . ARG A 379 ? 0.63193 0.37885 0.55704 0.04966  -0.02601 -0.00746 359 ARG A CG  
5509 C  CD  . ARG A 379 ? 0.80845 0.55410 0.72744 0.06221  -0.02819 -0.01984 359 ARG A CD  
5510 N  NE  . ARG A 379 ? 0.75454 0.52593 0.67330 0.06853  -0.02225 -0.02272 359 ARG A NE  
5511 C  CZ  . ARG A 379 ? 0.75016 0.53255 0.66963 0.07539  -0.01943 -0.01829 359 ARG A CZ  
5512 N  NH1 . ARG A 379 ? 0.75042 0.52109 0.66927 0.07717  -0.02166 -0.01023 359 ARG A NH1 
5513 N  NH2 . ARG A 379 ? 0.64142 0.44658 0.56224 0.08060  -0.01487 -0.02181 359 ARG A NH2 
5527 N  N   . ARG A 380 ? 0.45756 0.23393 0.39174 0.02983  -0.01197 0.02014  360 ARG A N   
5528 C  CA  . ARG A 380 ? 0.47340 0.24197 0.40292 0.03164  -0.01094 0.03071  360 ARG A CA  
5529 C  C   . ARG A 380 ? 0.46794 0.23925 0.40074 0.02087  -0.00566 0.04210  360 ARG A C   
5530 O  O   . ARG A 380 ? 0.49115 0.24936 0.42033 0.01955  -0.00545 0.05218  360 ARG A O   
5531 C  CB  . ARG A 380 ? 0.49528 0.27739 0.41866 0.04177  -0.00929 0.03025  360 ARG A CB  
5532 C  CG  . ARG A 380 ? 0.51508 0.29465 0.43646 0.05380  -0.01377 0.02051  360 ARG A CG  
5533 C  CD  . ARG A 380 ? 0.50990 0.30115 0.42784 0.06357  -0.01342 0.02158  360 ARG A CD  
5534 N  NE  . ARG A 380 ? 0.49281 0.27314 0.40486 0.06504  -0.01492 0.03219  360 ARG A NE  
5535 C  CZ  . ARG A 380 ? 0.50471 0.29444 0.41283 0.07164  -0.01537 0.03562  360 ARG A CZ  
5536 N  NH1 . ARG A 380 ? 0.48317 0.29332 0.39467 0.07717  -0.01462 0.02940  360 ARG A NH1 
5537 N  NH2 . ARG A 380 ? 0.52873 0.30779 0.42935 0.07191  -0.01667 0.04610  360 ARG A NH2 
5551 N  N   . LEU A 381 ? 0.44801 0.23542 0.38759 0.01354  -0.00133 0.04094  361 LEU A N   
5552 C  CA  . LEU A 381 ? 0.45664 0.24969 0.40150 0.00358  0.00477  0.05075  361 LEU A CA  
5553 C  C   . LEU A 381 ? 0.41898 0.21047 0.37676 -0.00643 0.00297  0.04827  361 LEU A C   
5554 O  O   . LEU A 381 ? 0.41352 0.22159 0.37849 -0.01149 0.00673  0.04702  361 LEU A O   
5555 C  CB  . LEU A 381 ? 0.44278 0.25799 0.38474 0.00484  0.01155  0.05183  361 LEU A CB  
5556 C  CG  . LEU A 381 ? 0.42770 0.24843 0.35809 0.01502  0.01154  0.05119  361 LEU A CG  
5557 C  CD1 . LEU A 381 ? 0.42903 0.27067 0.35758 0.01512  0.01694  0.05048  361 LEU A CD1 
5558 C  CD2 . LEU A 381 ? 0.44432 0.25015 0.36557 0.01785  0.01104  0.06117  361 LEU A CD2 
5570 N  N   . PRO A 382 ? 0.44313 0.21438 0.40417 -0.00886 -0.00399 0.04643  362 PRO A N   
5571 C  CA  . PRO A 382 ? 0.46283 0.23265 0.43535 -0.01700 -0.00840 0.04091  362 PRO A CA  
5572 C  C   . PRO A 382 ? 0.49345 0.27212 0.48000 -0.02938 -0.00380 0.04944  362 PRO A C   
5573 O  O   . PRO A 382 ? 0.46815 0.25271 0.46522 -0.03546 -0.00688 0.04433  362 PRO A O   
5574 C  CB  . PRO A 382 ? 0.50370 0.24622 0.47496 -0.01650 -0.01755 0.03802  362 PRO A CB  
5575 C  CG  . PRO A 382 ? 0.50083 0.23027 0.46421 -0.01234 -0.01595 0.04746  362 PRO A CG  
5576 C  CD  . PRO A 382 ? 0.46436 0.21216 0.41825 -0.00328 -0.00968 0.04759  362 PRO A CD  
5584 N  N   . ASP A 383 ? 0.45693 0.23624 0.44432 -0.03326 0.00315  0.06244  363 ASP A N   
5585 C  CA  . ASP A 383 ? 0.42823 0.21865 0.43037 -0.04455 0.00920  0.07124  363 ASP A CA  
5586 C  C   . ASP A 383 ? 0.46715 0.28056 0.46609 -0.04207 0.01978  0.07517  363 ASP A C   
5587 O  O   . ASP A 383 ? 0.46347 0.28555 0.46991 -0.04860 0.02788  0.08549  363 ASP A O   
5588 C  CB  . ASP A 383 ? 0.47057 0.24440 0.47825 -0.05264 0.00988  0.08393  363 ASP A CB  
5589 C  CG  . ASP A 383 ? 0.50935 0.27531 0.50197 -0.04697 0.01496  0.09369  363 ASP A CG  
5590 O  OD1 . ASP A 383 ? 0.50545 0.27508 0.48282 -0.03588 0.01566  0.08949  363 ASP A OD1 
5591 O  OD2 . ASP A 383 ? 0.55275 0.30753 0.54949 -0.05425 0.01745  0.10621  363 ASP A OD2 
5596 N  N   . LEU A 384 ? 0.40964 0.23288 0.39789 -0.03271 0.01980  0.06689  364 LEU A N   
5597 C  CA  . LEU A 384 ? 0.41350 0.25674 0.39745 -0.02953 0.02802  0.06835  364 LEU A CA  
5598 C  C   . LEU A 384 ? 0.42267 0.28205 0.42220 -0.03757 0.03319  0.07085  364 LEU A C   
5599 O  O   . LEU A 384 ? 0.40813 0.26973 0.42049 -0.04270 0.02813  0.06538  364 LEU A O   
5600 C  CB  . LEU A 384 ? 0.37662 0.22786 0.35157 -0.02046 0.02499  0.05732  364 LEU A CB  
5601 C  CG  . LEU A 384 ? 0.36245 0.23025 0.32982 -0.01559 0.03129  0.05751  364 LEU A CG  
5602 C  CD1 . LEU A 384 ? 0.37303 0.23391 0.32601 -0.01039 0.03429  0.06514  364 LEU A CD1 
5603 C  CD2 . LEU A 384 ? 0.35665 0.23226 0.32043 -0.00946 0.02703  0.04631  364 LEU A CD2 
5615 N  N   . ARG A 385 ? 0.39296 0.26364 0.39103 -0.03813 0.04315  0.07913  365 ARG A N   
5616 C  CA  . ARG A 385 ? 0.39126 0.28040 0.40368 -0.04338 0.04924  0.08085  365 ARG A CA  
5617 C  C   . ARG A 385 ? 0.36090 0.26412 0.36319 -0.03761 0.05880  0.08343  365 ARG A C   
5618 O  O   . ARG A 385 ? 0.36588 0.26355 0.35113 -0.03186 0.06186  0.08728  365 ARG A O   
5619 C  CB  . ARG A 385 ? 0.50238 0.38929 0.53226 -0.05440 0.05212  0.09097  365 ARG A CB  
5620 C  CG  . ARG A 385 ? 0.52131 0.40129 0.54413 -0.05577 0.06007  0.10431  365 ARG A CG  
5621 C  CD  . ARG A 385 ? 0.57945 0.46276 0.62340 -0.06794 0.06521  0.11570  365 ARG A CD  
5622 N  NE  . ARG A 385 ? 0.57392 0.45091 0.60925 -0.06914 0.07412  0.12976  365 ARG A NE  
5623 C  CZ  . ARG A 385 ? 0.61179 0.46679 0.63872 -0.07027 0.06997  0.13550  365 ARG A CZ  
5624 N  NH1 . ARG A 385 ? 0.79449 0.63161 0.82280 -0.07096 0.05739  0.12839  365 ARG A NH1 
5625 N  NH2 . ARG A 385 ? 0.60443 0.45439 0.61970 -0.06985 0.07836  0.14829  365 ARG A NH2 
5639 N  N   . LEU A 386 ? 0.37399 0.29472 0.38661 -0.03884 0.06277  0.08099  366 LEU A N   
5640 C  CA  . LEU A 386 ? 0.36956 0.30338 0.37389 -0.03347 0.07185  0.08267  366 LEU A CA  
5641 C  C   . LEU A 386 ? 0.43703 0.37255 0.44125 -0.03644 0.08291  0.09559  366 LEU A C   
5642 O  O   . LEU A 386 ? 0.46125 0.39610 0.48135 -0.04509 0.08513  0.10326  366 LEU A O   
5643 C  CB  . LEU A 386 ? 0.39597 0.34696 0.41328 -0.03389 0.07283  0.07689  366 LEU A CB  
5644 C  CG  . LEU A 386 ? 0.40200 0.35421 0.41747 -0.03027 0.06399  0.06509  366 LEU A CG  
5645 C  CD1 . LEU A 386 ? 0.49358 0.46080 0.52628 -0.03300 0.06407  0.06180  366 LEU A CD1 
5646 C  CD2 . LEU A 386 ? 0.39164 0.34383 0.38764 -0.02136 0.06454  0.06069  366 LEU A CD2 
5658 N  N   . VAL A 387 ? 0.38016 0.31736 0.36586 -0.02950 0.08978  0.09849  367 VAL A N   
5659 C  CA  . VAL A 387 ? 0.41619 0.35430 0.39830 -0.03156 0.10117  0.11144  367 VAL A CA  
5660 C  C   . VAL A 387 ? 0.54374 0.49918 0.54755 -0.03766 0.11012  0.11636  367 VAL A C   
5661 O  O   . VAL A 387 ? 0.64183 0.59740 0.65658 -0.04518 0.11646  0.12782  367 VAL A O   
5662 C  CB  . VAL A 387 ? 0.43042 0.36777 0.38636 -0.02194 0.10649  0.11233  367 VAL A CB  
5663 C  CG1 . VAL A 387 ? 0.46800 0.41307 0.42067 -0.02261 0.12100  0.12385  367 VAL A CG1 
5664 C  CG2 . VAL A 387 ? 0.42251 0.34111 0.36047 -0.01827 0.09878  0.11289  367 VAL A CG2 
5674 N  N   . ALA A 388 ? 0.59215 0.56268 0.60350 -0.03462 0.11084  0.10849  368 ALA A N   
5675 C  CA  . ALA A 388 ? 0.69881 0.68782 0.73367 -0.03940 0.11803  0.11175  368 ALA A CA  
5676 C  C   . ALA A 388 ? 0.77620 0.77014 0.82852 -0.04206 0.10744  0.10167  368 ALA A C   
5677 O  O   . ALA A 388 ? 0.74020 0.73797 0.78579 -0.03542 0.10349  0.09173  368 ALA A O   
5678 C  CB  . ALA A 388 ? 0.65761 0.66084 0.68389 -0.03153 0.13008  0.11242  368 ALA A CB  
5684 N  N   . ASP A 389 ? 0.77185 0.76423 0.84546 -0.05195 0.10210  0.10436  369 ASP A N   
5685 C  CA  . ASP A 389 ? 0.78458 0.77910 0.87242 -0.05470 0.09059  0.09493  369 ASP A CA  
5686 C  C   . ASP A 389 ? 0.91547 0.93013 1.01611 -0.05170 0.09361  0.09066  369 ASP A C   
5687 O  O   . ASP A 389 ? 0.90152 0.91783 1.00768 -0.05111 0.08407  0.08159  369 ASP A O   
5688 C  CB  . ASP A 389 ? 0.77952 0.76859 0.88831 -0.06634 0.08429  0.09920  369 ASP A CB  
5691 N  N   . ASP A 390 ? 0.94282 0.97245 1.04771 -0.04924 0.10675  0.09708  370 ASP A N   
5692 C  CA  . ASP A 390 ? 0.96022 1.00852 1.07578 -0.04439 0.11052  0.09293  370 ASP A CA  
5693 C  C   . ASP A 390 ? 0.84017 0.88918 0.93210 -0.03264 0.11716  0.08891  370 ASP A C   
5694 O  O   . ASP A 390 ? 0.82655 0.89051 0.92344 -0.02725 0.12567  0.08891  370 ASP A O   
5695 C  CB  . ASP A 390 ? 0.90141 0.96907 1.04423 -0.04997 0.12025  0.10230  370 ASP A CB  
5696 C  CG  . ASP A 390 ? 0.97897 1.04483 1.11566 -0.05252 0.13083  0.11341  370 ASP A CG  
5697 O  OD1 . ASP A 390 ? 0.96448 1.01529 1.07559 -0.04885 0.13283  0.11506  370 ASP A OD1 
5698 O  OD2 . ASP A 390 ? 1.02814 1.10678 1.18324 -0.05768 0.13485  0.11891  370 ASP A OD2 
5703 N  N   . SER A 391 ? 0.88188 0.91460 0.94846 -0.02832 0.11282  0.08515  371 SER A N   
5704 C  CA  . SER A 391 ? 0.84095 0.87196 0.88459 -0.01784 0.11593  0.07988  371 SER A CA  
5705 C  C   . SER A 391 ? 0.70252 0.73654 0.74780 -0.01361 0.10764  0.06874  371 SER A C   
5706 O  O   . SER A 391 ? 0.64272 0.67417 0.69825 -0.01805 0.09726  0.06422  371 SER A O   
5707 C  CB  . SER A 391 ? 0.79667 0.80996 0.81503 -0.01534 0.11278  0.08016  371 SER A CB  
5708 O  OG  . SER A 391 ? 0.71055 0.71187 0.72972 -0.01936 0.10053  0.07589  371 SER A OG  
5714 N  N   . VAL A 392 ? 0.64324 0.68228 0.67806 -0.00490 0.11238  0.06457  372 VAL A N   
5715 C  CA  . VAL A 392 ? 0.60451 0.64194 0.63395 0.00024  0.10445  0.05432  372 VAL A CA  
5716 C  C   . VAL A 392 ? 0.54757 0.57259 0.54945 0.00652  0.10292  0.05056  372 VAL A C   
5717 O  O   . VAL A 392 ? 0.56035 0.58588 0.54794 0.01300  0.11083  0.05158  372 VAL A O   
5718 C  CB  . VAL A 392 ? 0.57084 0.62250 0.61190 0.00530  0.10924  0.05172  372 VAL A CB  
5719 C  CG1 . VAL A 392 ? 0.63097 0.69674 0.70161 -0.00126 0.11065  0.05652  372 VAL A CG1 
5720 C  CG2 . VAL A 392 ? 0.56988 0.62550 0.59779 0.01331  0.12189  0.05410  372 VAL A CG2 
5730 N  N   . LEU A 393 ? 0.48437 0.49921 0.47908 0.00492  0.09337  0.04653  373 LEU A N   
5731 C  CA  . LEU A 393 ? 0.44138 0.44531 0.41222 0.00997  0.09142  0.04415  373 LEU A CA  
5732 C  C   . LEU A 393 ? 0.37694 0.38005 0.33880 0.01605  0.08705  0.03555  373 LEU A C   
5733 O  O   . LEU A 393 ? 0.39391 0.40111 0.36698 0.01498  0.08203  0.03093  373 LEU A O   
5734 C  CB  . LEU A 393 ? 0.38162 0.37491 0.34871 0.00600  0.08325  0.04418  373 LEU A CB  
5735 C  CG  . LEU A 393 ? 0.41496 0.40508 0.38853 0.00011  0.08647  0.05277  373 LEU A CG  
5736 C  CD1 . LEU A 393 ? 0.42074 0.40186 0.39705 -0.00387 0.07649  0.05014  373 LEU A CD1 
5737 C  CD2 . LEU A 393 ? 0.43913 0.42378 0.39557 0.00338  0.09349  0.05930  373 LEU A CD2 
5749 N  N   . PRO A 394 ? 0.37771 0.37456 0.31884 0.02232  0.08812  0.03338  374 PRO A N   
5750 C  CA  . PRO A 394 ? 0.36743 0.36257 0.30101 0.02769  0.08381  0.02527  374 PRO A CA  
5751 C  C   . PRO A 394 ? 0.33471 0.32351 0.26664 0.02534  0.07221  0.02000  374 PRO A C   
5752 O  O   . PRO A 394 ? 0.33691 0.31994 0.26393 0.02281  0.06769  0.02141  374 PRO A O   
5753 C  CB  . PRO A 394 ? 0.43971 0.42920 0.35069 0.03481  0.08837  0.02492  374 PRO A CB  
5754 C  CG  . PRO A 394 ? 0.47552 0.46025 0.37870 0.03247  0.09050  0.03192  374 PRO A CG  
5755 C  CD  . PRO A 394 ? 0.47102 0.46288 0.39490 0.02541  0.09452  0.03866  374 PRO A CD  
5763 N  N   . LEU A 395 ? 0.33224 0.32263 0.26912 0.02653  0.06775  0.01423  375 LEU A N   
5764 C  CA  . LEU A 395 ? 0.29142 0.27711 0.22701 0.02458  0.05783  0.00950  375 LEU A CA  
5765 C  C   . LEU A 395 ? 0.33159 0.31028 0.25151 0.02956  0.05429  0.00430  375 LEU A C   
5766 O  O   . LEU A 395 ? 0.35573 0.33366 0.26866 0.03520  0.05865  0.00224  375 LEU A O   
5767 C  CB  . LEU A 395 ? 0.29011 0.28089 0.24125 0.02187  0.05435  0.00740  375 LEU A CB  
5768 C  CG  . LEU A 395 ? 0.33648 0.33349 0.30392 0.01641  0.05522  0.01126  375 LEU A CG  
5769 C  CD1 . LEU A 395 ? 0.30842 0.31105 0.28955 0.01564  0.05247  0.00923  375 LEU A CD1 
5770 C  CD2 . LEU A 395 ? 0.32740 0.32026 0.29397 0.01183  0.04983  0.01194  375 LEU A CD2 
5782 N  N   . ARG A 396 ? 0.32126 0.29501 0.23618 0.02762  0.04628  0.00200  376 ARG A N   
5783 C  CA  . ARG A 396 ? 0.35130 0.31773 0.25256 0.03108  0.04084  -0.00306 376 ARG A CA  
5784 C  C   . ARG A 396 ? 0.34391 0.30887 0.24894 0.03243  0.03789  -0.00800 376 ARG A C   
5785 O  O   . ARG A 396 ? 0.33422 0.30183 0.25112 0.02824  0.03390  -0.00826 376 ARG A O   
5786 C  CB  . ARG A 396 ? 0.39597 0.36005 0.29541 0.02777  0.03287  -0.00347 376 ARG A CB  
5787 C  CG  . ARG A 396 ? 0.59278 0.55006 0.48163 0.02961  0.02526  -0.00854 376 ARG A CG  
5788 C  CD  . ARG A 396 ? 0.78775 0.74350 0.67084 0.02861  0.01940  -0.00760 376 ARG A CD  
5789 N  NE  . ARG A 396 ? 0.91610 0.86406 0.78364 0.03235  0.01392  -0.01165 376 ARG A NE  
5790 C  CZ  . ARG A 396 ? 0.99740 0.94348 0.85896 0.03228  0.00692  -0.01183 376 ARG A CZ  
5791 N  NH1 . ARG A 396 ? 0.93027 0.88209 0.80048 0.02932  0.00515  -0.00822 376 ARG A NH1 
5792 N  NH2 . ARG A 396 ? 0.94440 0.88247 0.79098 0.03576  0.00101  -0.01614 376 ARG A NH2 
5806 N  N   . PRO A 397 ? 0.33117 0.29073 0.22517 0.03860  0.03932  -0.01208 377 PRO A N   
5807 C  CA  . PRO A 397 ? 0.33380 0.28874 0.22998 0.04018  0.03454  -0.01738 377 PRO A CA  
5808 C  C   . PRO A 397 ? 0.38637 0.33485 0.28028 0.03595  0.02369  -0.02010 377 PRO A C   
5809 O  O   . PRO A 397 ? 0.44265 0.38506 0.32416 0.03681  0.01915  -0.02222 377 PRO A O   
5810 C  CB  . PRO A 397 ? 0.40361 0.35296 0.28573 0.04894  0.03906  -0.02159 377 PRO A CB  
5811 C  CG  . PRO A 397 ? 0.55262 0.50220 0.42167 0.05132  0.04437  -0.01874 377 PRO A CG  
5812 C  CD  . PRO A 397 ? 0.39878 0.35630 0.27824 0.04500  0.04652  -0.01166 377 PRO A CD  
5820 N  N   . ALA A 398 ? 0.31159 0.26252 0.21837 0.03084  0.01954  -0.01918 378 ALA A N   
5821 C  CA  . ALA A 398 ? 0.30413 0.25130 0.21249 0.02566  0.01036  -0.02027 378 ALA A CA  
5822 C  C   . ALA A 398 ? 0.31623 0.26537 0.23722 0.02209  0.00841  -0.01890 378 ALA A C   
5823 O  O   . ALA A 398 ? 0.30134 0.25802 0.23164 0.02116  0.01304  -0.01563 378 ALA A O   
5824 C  CB  . ALA A 398 ? 0.36455 0.31719 0.27463 0.02119  0.00877  -0.01687 378 ALA A CB  
5830 N  N   . ASN A 399 ? 0.31999 0.26195 0.24133 0.01958  0.00091  -0.02091 379 ASN A N   
5831 C  CA  . ASN A 399 ? 0.30964 0.25203 0.24127 0.01644  -0.00126 -0.01880 379 ASN A CA  
5832 C  C   . ASN A 399 ? 0.28904 0.23771 0.22837 0.00884  -0.00386 -0.01418 379 ASN A C   
5833 O  O   . ASN A 399 ? 0.29900 0.24735 0.24475 0.00576  -0.00617 -0.01174 379 ASN A O   
5834 C  CB  . ASN A 399 ? 0.33447 0.26421 0.26279 0.01818  -0.00744 -0.02261 379 ASN A CB  
5835 C  CG  . ASN A 399 ? 0.32564 0.24840 0.25138 0.01256  -0.01615 -0.02332 379 ASN A CG  
5836 O  OD1 . ASN A 399 ? 0.31856 0.24818 0.24754 0.00696  -0.01741 -0.02022 379 ASN A OD1 
5837 N  ND2 . ASN A 399 ? 0.36815 0.27721 0.28917 0.01411  -0.02249 -0.02745 379 ASN A ND2 
5844 N  N   . PHE A 400 ? 0.29456 0.24907 0.23296 0.00639  -0.00323 -0.01269 380 PHE A N   
5845 C  CA  . PHE A 400 ? 0.26343 0.22413 0.20825 0.00018  -0.00543 -0.00901 380 PHE A CA  
5846 C  C   . PHE A 400 ? 0.28205 0.25206 0.22951 0.00026  -0.00016 -0.00661 380 PHE A C   
5847 O  O   . PHE A 400 ? 0.27142 0.24605 0.22431 -0.00150 0.00198  -0.00413 380 PHE A O   
5848 C  CB  . PHE A 400 ? 0.29038 0.24901 0.23345 -0.00288 -0.01145 -0.00990 380 PHE A CB  
5849 C  CG  . PHE A 400 ? 0.27435 0.24103 0.22572 -0.00918 -0.01309 -0.00569 380 PHE A CG  
5850 C  CD1 . PHE A 400 ? 0.26631 0.23680 0.22377 -0.01265 -0.01142 -0.00170 380 PHE A CD1 
5851 C  CD2 . PHE A 400 ? 0.29597 0.26713 0.24895 -0.01131 -0.01639 -0.00554 380 PHE A CD2 
5852 C  CE1 . PHE A 400 ? 0.29230 0.27092 0.25635 -0.01800 -0.01181 0.00247  380 PHE A CE1 
5853 C  CE2 . PHE A 400 ? 0.30303 0.28356 0.26527 -0.01671 -0.01706 -0.00143 380 PHE A CE2 
5854 C  CZ  . PHE A 400 ? 0.31640 0.30072 0.28372 -0.01998 -0.01418 0.00261  380 PHE A CZ  
5864 N  N   . VAL A 401 ? 0.26797 0.23921 0.21044 0.00273  0.00141  -0.00754 381 VAL A N   
5865 C  CA  . VAL A 401 ? 0.24837 0.22597 0.19242 0.00336  0.00580  -0.00545 381 VAL A CA  
5866 C  C   . VAL A 401 ? 0.27947 0.25452 0.21760 0.00805  0.01051  -0.00609 381 VAL A C   
5867 O  O   . VAL A 401 ? 0.29758 0.26759 0.22695 0.01124  0.00957  -0.00820 381 VAL A O   
5868 C  CB  . VAL A 401 ? 0.25406 0.23602 0.19864 0.00187  0.00307  -0.00462 381 VAL A CB  
5869 C  CG1 . VAL A 401 ? 0.31295 0.29926 0.25834 0.00357  0.00722  -0.00286 381 VAL A CG1 
5870 C  CG2 . VAL A 401 ? 0.28594 0.27261 0.23780 -0.00307 -0.00011 -0.00296 381 VAL A CG2 
5880 N  N   . SER A 402 ? 0.26166 0.24009 0.20408 0.00829  0.01546  -0.00403 382 SER A N   
5881 C  CA  . SER A 402 ? 0.27098 0.24813 0.20962 0.01188  0.02094  -0.00331 382 SER A CA  
5882 C  C   . SER A 402 ? 0.26902 0.24971 0.21305 0.01049  0.02475  -0.00018 382 SER A C   
5883 O  O   . SER A 402 ? 0.26628 0.25003 0.21770 0.00740  0.02352  0.00041  382 SER A O   
5884 C  CB  . SER A 402 ? 0.26576 0.24167 0.20599 0.01438  0.02343  -0.00471 382 SER A CB  
5885 O  OG  . SER A 402 ? 0.30597 0.28276 0.24380 0.01787  0.03023  -0.00326 382 SER A OG  
5891 N  N   . GLY A 403 ? 0.26319 0.24230 0.20230 0.01291  0.02918  0.00184  383 GLY A N   
5892 C  CA  . GLY A 403 ? 0.27942 0.25995 0.22362 0.01148  0.03318  0.00536  383 GLY A CA  
5893 C  C   . GLY A 403 ? 0.27843 0.25665 0.21567 0.01436  0.03895  0.00848  383 GLY A C   
5894 O  O   . GLY A 403 ? 0.27699 0.25351 0.20584 0.01814  0.04105  0.00739  383 GLY A O   
5898 N  N   . LEU A 404 ? 0.26271 0.23998 0.20262 0.01268  0.04166  0.01257  384 LEU A N   
5899 C  CA  . LEU A 404 ? 0.29641 0.27191 0.23099 0.01445  0.04830  0.01727  384 LEU A CA  
5900 C  C   . LEU A 404 ? 0.29212 0.26195 0.20996 0.01891  0.04755  0.01756  384 LEU A C   
5901 O  O   . LEU A 404 ? 0.30304 0.26963 0.21618 0.01946  0.04170  0.01629  384 LEU A O   
5902 C  CB  . LEU A 404 ? 0.30761 0.28128 0.24907 0.01075  0.05006  0.02214  384 LEU A CB  
5903 C  CG  . LEU A 404 ? 0.28711 0.26583 0.24509 0.00595  0.05132  0.02308  384 LEU A CG  
5904 C  CD1 . LEU A 404 ? 0.33336 0.30698 0.29701 0.00185  0.04936  0.02589  384 LEU A CD1 
5905 C  CD2 . LEU A 404 ? 0.33253 0.31693 0.29470 0.00652  0.05942  0.02682  384 LEU A CD2 
5917 N  N   . GLU A 405 ? 0.31334 0.28239 0.22206 0.02249  0.05353  0.01943  385 GLU A N   
5918 C  CA  . GLU A 405 ? 0.33516 0.29767 0.22541 0.02709  0.05265  0.02017  385 GLU A CA  
5919 C  C   . GLU A 405 ? 0.37362 0.33129 0.25892 0.02664  0.05495  0.02716  385 GLU A C   
5920 O  O   . GLU A 405 ? 0.38931 0.34088 0.26177 0.02961  0.05060  0.02776  385 GLU A O   
5921 C  CB  . GLU A 405 ? 0.40497 0.36714 0.28352 0.03229  0.05849  0.01916  385 GLU A CB  
5922 C  CG  . GLU A 405 ? 0.42879 0.39225 0.30824 0.03427  0.05525  0.01187  385 GLU A CG  
5923 C  CD  . GLU A 405 ? 0.46188 0.42296 0.32666 0.04107  0.06074  0.00985  385 GLU A CD  
5924 O  OE1 . GLU A 405 ? 0.51577 0.47552 0.36920 0.04420  0.06816  0.01470  385 GLU A OE1 
5925 O  OE2 . GLU A 405 ? 0.55340 0.51337 0.41734 0.04364  0.05796  0.00348  385 GLU A OE2 
5932 N  N   . SER A 406 ? 0.33803 0.29771 0.23330 0.02297  0.06118  0.03285  386 SER A N   
5933 C  CA  . SER A 406 ? 0.36273 0.31633 0.25269 0.02230  0.06460  0.04081  386 SER A CA  
5934 C  C   . SER A 406 ? 0.36013 0.31634 0.26859 0.01576  0.06730  0.04460  386 SER A C   
5935 O  O   . SER A 406 ? 0.35632 0.32054 0.27828 0.01308  0.06952  0.04252  386 SER A O   
5936 C  CB  . SER A 406 ? 0.41637 0.36882 0.29154 0.02622  0.07330  0.04595  386 SER A CB  
5937 O  OG  . SER A 406 ? 0.46851 0.41519 0.34012 0.02448  0.07760  0.05528  386 SER A OG  
5943 N  N   . MET A 407 ? 0.34164 0.29017 0.25099 0.01330  0.06579  0.04974  387 MET A N   
5944 C  CA  A MET A 407 ? 0.34106 0.28964 0.26733 0.00662  0.06682  0.05299  387 MET A CA  
5945 C  CA  B MET A 407 ? 0.34111 0.28977 0.26747 0.00658  0.06693  0.05306  387 MET A CA  
5946 C  C   . MET A 407 ? 0.32831 0.26604 0.24944 0.00522  0.06825  0.06146  387 MET A C   
5947 O  O   . MET A 407 ? 0.32566 0.25439 0.24678 0.00500  0.06163  0.06072  387 MET A O   
5948 C  CB  A MET A 407 ? 0.33197 0.28074 0.26874 0.00447  0.05854  0.04600  387 MET A CB  
5949 C  CB  B MET A 407 ? 0.33132 0.28084 0.26902 0.00420  0.05894  0.04601  387 MET A CB  
5950 C  CG  A MET A 407 ? 0.29114 0.23886 0.24433 -0.00229 0.05786  0.04782  387 MET A CG  
5951 C  CG  B MET A 407 ? 0.35990 0.31602 0.31684 -0.00207 0.06020  0.04569  387 MET A CG  
5952 S  SD  A MET A 407 ? 0.37983 0.32948 0.34016 -0.00267 0.04860  0.03775  387 MET A SD  
5953 S  SD  B MET A 407 ? 0.32248 0.27370 0.29247 -0.00720 0.05195  0.04177  387 MET A SD  
5954 C  CE  A MET A 407 ? 0.28415 0.22079 0.24730 -0.00518 0.04347  0.03890  387 MET A CE  
5955 C  CE  B MET A 407 ? 0.27271 0.21852 0.22968 -0.00109 0.04487  0.03547  387 MET A CE  
5972 N  N   . PRO A 408 ? 0.31942 0.25733 0.23593 0.00453  0.07716  0.07002  388 PRO A N   
5973 C  CA  . PRO A 408 ? 0.35865 0.28514 0.27052 0.00234  0.07897  0.07977  388 PRO A CA  
5974 C  C   . PRO A 408 ? 0.37250 0.29470 0.30304 -0.00551 0.07614  0.08182  388 PRO A C   
5975 O  O   . PRO A 408 ? 0.34661 0.27773 0.29480 -0.01112 0.07874  0.08130  388 PRO A O   
5976 C  CB  . PRO A 408 ? 0.38470 0.31587 0.28986 0.00257  0.09105  0.08859  388 PRO A CB  
5977 C  CG  . PRO A 408 ? 0.41648 0.35771 0.31401 0.00849  0.09352  0.08172  388 PRO A CG  
5978 C  CD  . PRO A 408 ? 0.37562 0.32344 0.28809 0.00696  0.08645  0.07146  388 PRO A CD  
5986 N  N   . VAL A 409 ? 0.37439 0.28224 0.30085 -0.00544 0.06997  0.08381  389 VAL A N   
5987 C  CA  . VAL A 409 ? 0.35413 0.25355 0.29514 -0.01198 0.06538  0.08478  389 VAL A CA  
5988 C  C   . VAL A 409 ? 0.37119 0.25404 0.30481 -0.01302 0.06538  0.09468  389 VAL A C   
5989 O  O   . VAL A 409 ? 0.40495 0.28114 0.32060 -0.00679 0.06527  0.09802  389 VAL A O   
5990 C  CB  . VAL A 409 ? 0.35938 0.25642 0.30433 -0.00969 0.05507  0.07347  389 VAL A CB  
5991 C  CG1 . VAL A 409 ? 0.33556 0.24728 0.28959 -0.01030 0.05476  0.06519  389 VAL A CG1 
5992 C  CG2 . VAL A 409 ? 0.35515 0.24560 0.28422 -0.00110 0.04950  0.07007  389 VAL A CG2 
6002 N  N   . VAL A 410 ? 0.36861 0.24385 0.31623 -0.02120 0.06476  0.09975  390 VAL A N   
6003 C  CA  . VAL A 410 ? 0.37603 0.23281 0.31903 -0.02341 0.06351  0.10934  390 VAL A CA  
6004 C  C   . VAL A 410 ? 0.39335 0.23640 0.34658 -0.02637 0.05322  0.10398  390 VAL A C   
6005 O  O   . VAL A 410 ? 0.41568 0.26502 0.38194 -0.02915 0.04902  0.09514  390 VAL A O   
6006 C  CB  . VAL A 410 ? 0.43000 0.28787 0.37882 -0.03136 0.07373  0.12351  390 VAL A CB  
6007 C  CG1 . VAL A 410 ? 0.42631 0.29342 0.35830 -0.02598 0.08388  0.12929  390 VAL A CG1 
6008 C  CG2 . VAL A 410 ? 0.42445 0.29416 0.39772 -0.04077 0.07614  0.12270  390 VAL A CG2 
6018 N  N   . PHE A 411 ? 0.42233 0.24532 0.36822 -0.02527 0.04895  0.10954  391 PHE A N   
6019 C  CA  . PHE A 411 ? 0.44311 0.24892 0.39397 -0.02550 0.03848  0.10402  391 PHE A CA  
6020 C  C   . PHE A 411 ? 0.46417 0.24769 0.40689 -0.02550 0.03657  0.11451  391 PHE A C   
6021 O  O   . PHE A 411 ? 0.50314 0.28480 0.43147 -0.02182 0.04146  0.12356  391 PHE A O   
6022 C  CB  . PHE A 411 ? 0.42712 0.23522 0.37109 -0.01550 0.03117  0.09055  391 PHE A CB  
6023 C  CG  . PHE A 411 ? 0.43655 0.24744 0.36297 -0.00545 0.03202  0.09122  391 PHE A CG  
6024 C  CD1 . PHE A 411 ? 0.44560 0.23951 0.36094 0.00086  0.02696  0.09471  391 PHE A CD1 
6025 C  CD2 . PHE A 411 ? 0.41100 0.24042 0.33234 -0.00220 0.03684  0.08826  391 PHE A CD2 
6026 C  CE1 . PHE A 411 ? 0.45518 0.25193 0.35513 0.01013  0.02635  0.09545  391 PHE A CE1 
6027 C  CE2 . PHE A 411 ? 0.43352 0.26475 0.33872 0.00670  0.03608  0.08854  391 PHE A CE2 
6028 C  CZ  . PHE A 411 ? 0.44660 0.26187 0.34155 0.01262  0.03068  0.09241  391 PHE A CZ  
6038 N  N   . THR A 412 ? 0.49125 0.25636 0.44188 -0.02926 0.02876  0.11317  392 THR A N   
6039 C  CA  . THR A 412 ? 0.52340 0.26433 0.46597 -0.02821 0.02510  0.12200  392 THR A CA  
6040 C  C   . THR A 412 ? 0.53334 0.26808 0.45851 -0.01439 0.01981  0.11721  392 THR A C   
6041 O  O   . THR A 412 ? 0.55929 0.29739 0.48476 -0.00729 0.01362  0.10397  392 THR A O   
6042 C  CB  . THR A 412 ? 0.52053 0.24132 0.47569 -0.03511 0.01671  0.12030  392 THR A CB  
6043 O  OG1 . THR A 412 ? 0.54282 0.27038 0.51615 -0.04888 0.02128  0.12635  392 THR A OG1 
6044 C  CG2 . THR A 412 ? 0.56371 0.25709 0.50975 -0.03313 0.01206  0.12927  392 THR A CG2 
6052 N  N   . PRO A 413 ? 0.54500 0.27147 0.45510 -0.01013 0.02205  0.12797  393 PRO A N   
6053 C  CA  . PRO A 413 ? 0.57251 0.29446 0.46749 0.00317  0.01622  0.12403  393 PRO A CA  
6054 C  C   . PRO A 413 ? 0.63837 0.34024 0.53577 0.00860  0.00528  0.11723  393 PRO A C   
6055 O  O   . PRO A 413 ? 0.66324 0.34664 0.56884 0.00214  0.00160  0.11971  393 PRO A O   
6056 C  CB  . PRO A 413 ? 0.60980 0.32315 0.48871 0.00445  0.02034  0.13938  393 PRO A CB  
6057 C  CG  . PRO A 413 ? 0.69809 0.42143 0.58168 -0.00646 0.03162  0.14915  393 PRO A CG  
6058 C  CD  . PRO A 413 ? 0.57465 0.29871 0.48033 -0.01701 0.03091  0.14459  393 PRO A CD  
6066 N  N   . SER A 414 ? 0.62922 0.33440 0.51928 0.02100  -0.00010 0.10889  394 SER A N   
6067 C  CA  . SER A 414 ? 0.67427 0.36270 0.56494 0.02937  -0.00984 0.10147  394 SER A CA  
6068 C  C   . SER A 414 ? 0.69781 0.38817 0.57650 0.04298  -0.01377 0.10094  394 SER A C   
6069 O  O   . SER A 414 ? 0.65178 0.35950 0.52323 0.04550  -0.00980 0.10288  394 SER A O   
6070 C  CB  . SER A 414 ? 0.66517 0.36179 0.56705 0.02988  -0.01265 0.08595  394 SER A CB  
6071 O  OG  . SER A 414 ? 0.64650 0.36893 0.54791 0.03462  -0.00948 0.07797  394 SER A OG  
6077 N  N   . PRO A 415 ? 0.67902 0.35131 0.55556 0.05216  -0.02215 0.09839  395 PRO A N   
6078 C  CA  . PRO A 415 ? 0.68089 0.35602 0.54852 0.06582  -0.02697 0.09772  395 PRO A CA  
6079 C  C   . PRO A 415 ? 0.64995 0.34812 0.52378 0.07329  -0.02762 0.08371  395 PRO A C   
6080 O  O   . PRO A 415 ? 0.70473 0.40775 0.58847 0.07145  -0.02723 0.07294  395 PRO A O   
6081 C  CB  . PRO A 415 ? 0.75991 0.40760 0.62631 0.07282  -0.03561 0.09903  395 PRO A CB  
6082 C  CG  . PRO A 415 ? 0.81430 0.44706 0.69014 0.06224  -0.03543 0.09882  395 PRO A CG  
6083 C  CD  . PRO A 415 ? 0.73605 0.38082 0.61701 0.04933  -0.02771 0.09944  395 PRO A CD  
6091 N  N   . PRO A 416 ? 0.63139 0.34359 0.49956 0.08178  -0.02915 0.08373  396 PRO A N   
6092 C  CA  . PRO A 416 ? 0.64123 0.37635 0.51700 0.08834  -0.02968 0.07148  396 PRO A CA  
6093 C  C   . PRO A 416 ? 0.72793 0.45601 0.61037 0.09941  -0.03582 0.06226  396 PRO A C   
6094 O  O   . PRO A 416 ? 0.71042 0.41530 0.59004 0.10454  -0.04133 0.06528  396 PRO A O   
6095 C  CB  . PRO A 416 ? 0.59432 0.34296 0.46209 0.09371  -0.03114 0.07593  396 PRO A CB  
6096 C  CG  . PRO A 416 ? 0.73033 0.45740 0.58517 0.09577  -0.03477 0.08885  396 PRO A CG  
6097 C  CD  . PRO A 416 ? 0.71071 0.41944 0.56496 0.08475  -0.03038 0.09547  396 PRO A CD  
6105 N  N   . LEU A 417 ? 0.70086 0.44946 0.59200 0.10345  -0.03449 0.05100  397 LEU A N   
6106 C  CA  . LEU A 417 ? 0.72971 0.47753 0.62743 0.11548  -0.03864 0.04129  397 LEU A CA  
6107 C  C   . LEU A 417 ? 0.70603 0.46688 0.60509 0.12747  -0.04296 0.04190  397 LEU A C   
6108 O  O   . LEU A 417 ? 0.86460 0.61707 0.76624 0.13979  -0.04845 0.03903  397 LEU A O   
6109 C  CB  . LEU A 417 ? 0.63519 0.39873 0.54138 0.11346  -0.03411 0.02942  397 LEU A CB  
6110 C  CG  . LEU A 417 ? 0.72393 0.47961 0.63057 0.10133  -0.03046 0.02736  397 LEU A CG  
6111 C  CD1 . LEU A 417 ? 0.70636 0.47949 0.61960 0.10151  -0.02678 0.01555  397 LEU A CD1 
6112 C  CD2 . LEU A 417 ? 0.78984 0.51496 0.69347 0.10111  -0.03520 0.02855  397 LEU A CD2 
6124 C  CAA . 3QO B .   ? 0.33316 0.34690 0.33474 -0.03659 -0.03074 0.00924  401 3QO A CAA 
6125 C  CAB . 3QO B .   ? 0.28221 0.29478 0.27949 -0.03513 -0.02353 0.01110  401 3QO A CAB 
6126 C  CAC . 3QO B .   ? 0.34876 0.36459 0.34607 -0.03068 -0.03150 0.00564  401 3QO A CAC 
6127 C  CAD . 3QO B .   ? 0.22248 0.24841 0.20089 -0.01296 0.00527  0.00786  401 3QO A CAD 
6128 C  CAE . 3QO B .   ? 0.24067 0.28432 0.23316 -0.01418 0.00370  0.01039  401 3QO A CAE 
6129 C  CAF . 3QO B .   ? 0.27630 0.29002 0.26636 -0.02838 -0.01719 0.00908  401 3QO A CAF 
6130 C  CAG . 3QO B .   ? 0.35569 0.37185 0.34508 -0.02382 -0.02451 0.00425  401 3QO A CAG 
6131 C  CAH . 3QO B .   ? 0.25158 0.27062 0.22864 -0.01403 0.00012  0.00641  401 3QO A CAH 
6132 C  CAI . 3QO B .   ? 0.24671 0.28357 0.23843 -0.01607 -0.00276 0.00903  401 3QO A CAI 
6133 C  CAJ . 3QO B .   ? 0.29817 0.31279 0.27730 -0.01644 -0.01111 0.00416  401 3QO A CAJ 
6134 N  NAK . 3QO B .   ? 0.22947 0.26701 0.21445 -0.01273 0.00738  0.00960  401 3QO A NAK 
6135 C  CAL . 3QO B .   ? 0.27275 0.28796 0.25917 -0.02291 -0.01743 0.00578  401 3QO A CAL 
6136 C  CAM . 3QO B .   ? 0.27024 0.29388 0.25299 -0.01571 -0.00436 0.00673  401 3QO A CAM 
6148 C  CAD . 3QO C .   ? 0.58030 0.55602 0.55478 -0.03103 -0.06763 -0.01182 402 3QO A CAD 
6149 C  CAE . 3QO C .   ? 0.64157 0.64431 0.64781 -0.04151 -0.07093 -0.00332 402 3QO A CAE 
6150 C  CAH . 3QO C .   ? 0.60837 0.57297 0.57891 -0.03334 -0.07979 -0.01649 402 3QO A CAH 
6151 C  CAI . 3QO C .   ? 0.61349 0.60712 0.61925 -0.04523 -0.08390 -0.00712 402 3QO A CAI 
6152 C  CAJ . 3QO C .   ? 0.66592 0.62603 0.64869 -0.04425 -0.10414 -0.01984 402 3QO A CAJ 
6153 N  NAK . 3QO C .   ? 0.61533 0.60885 0.60621 -0.03483 -0.06342 -0.00570 402 3QO A NAK 
6154 C  CAL . 3QO C .   ? 0.67757 0.63885 0.67893 -0.05624 -0.11148 -0.01601 402 3QO A CAL 
6155 C  CAM . 3QO C .   ? 0.61372 0.58667 0.60004 -0.04093 -0.08892 -0.01430 402 3QO A CAM 
6162 C  CHA . HEM D .   ? 0.24538 0.29599 0.23537 -0.02449 0.01444  0.02161  403 HEM A CHA 
6163 C  CHB . HEM D .   ? 0.23664 0.25766 0.20327 -0.00963 0.01371  0.00703  403 HEM A CHB 
6164 C  CHC . HEM D .   ? 0.23933 0.27577 0.21463 0.00405  0.01658  0.00287  403 HEM A CHC 
6165 C  CHD . HEM D .   ? 0.21456 0.29265 0.22440 -0.00897 0.01574  0.01468  403 HEM A CHD 
6166 C  C1A . HEM D .   ? 0.22573 0.26516 0.20650 -0.02085 0.01355  0.01759  403 HEM A C1A 
6167 C  C2A . HEM D .   ? 0.25184 0.28097 0.22607 -0.02257 0.01169  0.01827  403 HEM A C2A 
6168 C  C3A . HEM D .   ? 0.22392 0.24652 0.19281 -0.01814 0.01160  0.01393  403 HEM A C3A 
6169 C  C4A . HEM D .   ? 0.23355 0.25995 0.20390 -0.01386 0.01330  0.01076  403 HEM A C4A 
6170 C  CMA . HEM D .   ? 0.23249 0.24515 0.19635 -0.01765 0.00938  0.01284  403 HEM A CMA 
6171 C  CAA . HEM D .   ? 0.24546 0.27178 0.21978 -0.02838 0.00994  0.02366  403 HEM A CAA 
6172 C  CBA . HEM D .   ? 0.25463 0.28121 0.22081 -0.02759 0.01330  0.02582  403 HEM A CBA 
6173 C  CGA . HEM D .   ? 0.28980 0.30818 0.25247 -0.03154 0.01002  0.03024  403 HEM A CGA 
6174 O  O1A . HEM D .   ? 0.29531 0.31354 0.24988 -0.03087 0.01200  0.03242  403 HEM A O1A 
6175 O  O2A . HEM D .   ? 0.28337 0.29435 0.24990 -0.03461 0.00508  0.03119  403 HEM A O2A 
6176 C  C1B . HEM D .   ? 0.21945 0.24264 0.18679 -0.00563 0.01501  0.00491  403 HEM A C1B 
6177 C  C2B . HEM D .   ? 0.23422 0.25103 0.19758 -0.00191 0.01590  0.00207  403 HEM A C2B 
6178 C  C3B . HEM D .   ? 0.22718 0.24706 0.19202 0.00168  0.01671  0.00117  403 HEM A C3B 
6179 C  C4B . HEM D .   ? 0.22928 0.25902 0.20016 0.00062  0.01636  0.00307  403 HEM A C4B 
6180 C  CMB . HEM D .   ? 0.27561 0.28447 0.23576 -0.00243 0.01538  0.00101  403 HEM A CMB 
6181 C  CAB . HEM D .   ? 0.23964 0.25387 0.20172 0.00607  0.01744  -0.00082 403 HEM A CAB 
6182 C  CBB . HEM D .   ? 0.31887 0.32611 0.27750 0.00655  0.01824  -0.00230 403 HEM A CBB 
6183 C  C1C . HEM D .   ? 0.22784 0.27625 0.21188 0.00268  0.01628  0.00511  403 HEM A C1C 
6184 C  C2C . HEM D .   ? 0.23659 0.29356 0.22719 0.00720  0.01617  0.00487  403 HEM A C2C 
6185 C  C3C . HEM D .   ? 0.23125 0.30112 0.23244 0.00387  0.01591  0.00788  403 HEM A C3C 
6186 C  C4C . HEM D .   ? 0.21484 0.28296 0.21518 -0.00306 0.01591  0.01039  403 HEM A C4C 
6187 C  CMC . HEM D .   ? 0.25342 0.30552 0.24050 0.01428  0.01622  0.00230  403 HEM A CMC 
6188 C  CAC . HEM D .   ? 0.25961 0.34472 0.27378 0.00637  0.01544  0.00927  403 HEM A CAC 
6189 C  CBC . HEM D .   ? 0.50510 0.59205 0.52085 0.01349  0.01489  0.00733  403 HEM A CBC 
6190 C  C1D . HEM D .   ? 0.22311 0.29774 0.23083 -0.01507 0.01601  0.01766  403 HEM A C1D 
6191 C  C2D . HEM D .   ? 0.24526 0.32933 0.26289 -0.02209 0.01627  0.02336  403 HEM A C2D 
6192 C  C3D . HEM D .   ? 0.22412 0.29914 0.23512 -0.02660 0.01590  0.02553  403 HEM A C3D 
6193 C  C4D . HEM D .   ? 0.21654 0.27806 0.21470 -0.02233 0.01548  0.02099  403 HEM A C4D 
6194 C  CMD . HEM D .   ? 0.25091 0.35284 0.28549 -0.02410 0.01641  0.02682  403 HEM A CMD 
6195 C  CAD . HEM D .   ? 0.23415 0.31247 0.25114 -0.03515 0.01573  0.03248  403 HEM A CAD 
6196 C  CBD . HEM D .   ? 0.24041 0.32701 0.25394 -0.03497 0.02415  0.03686  403 HEM A CBD 
6197 C  CGD . HEM D .   ? 0.25428 0.34233 0.27179 -0.04372 0.02443  0.04502  403 HEM A CGD 
6198 O  O1D . HEM D .   ? 0.25715 0.33503 0.27744 -0.04960 0.01711  0.04627  403 HEM A O1D 
6199 O  O2D . HEM D .   ? 0.25856 0.35727 0.27570 -0.04464 0.03211  0.05049  403 HEM A O2D 
6200 N  NA  . HEM D .   ? 0.22101 0.25760 0.19827 -0.01514 0.01425  0.01289  403 HEM A NA  
6201 N  NB  . HEM D .   ? 0.21220 0.24412 0.18490 -0.00440 0.01559  0.00558  403 HEM A NB  
6202 N  NC  . HEM D .   ? 0.20464 0.25929 0.19404 -0.00307 0.01588  0.00837  403 HEM A NC  
6203 N  ND  . HEM D .   ? 0.22411 0.28560 0.22076 -0.01586 0.01574  0.01644  403 HEM A ND  
6204 FE FE  . HEM D .   ? 0.22934 0.27517 0.21249 -0.00951 0.01551  0.01039  403 HEM A FE  
6235 O  O   . HOH E .   ? 0.79354 0.80528 0.84521 0.00583  -0.05311 0.01059  501 HOH A O   
6236 O  O   . HOH E .   ? 0.64661 0.60916 0.53639 0.02355  0.00063  -0.00530 502 HOH A O   
6237 O  O   . HOH E .   ? 0.73694 0.66913 0.56939 0.02962  -0.09670 -0.03230 503 HOH A O   
6238 O  O   . HOH E .   ? 0.53801 0.46712 0.55685 0.08077  -0.01338 -0.02395 504 HOH A O   
6239 O  O   . HOH E .   ? 0.81176 0.60884 0.72695 0.07311  -0.01746 -0.03722 505 HOH A O   
6240 O  O   . HOH E .   ? 0.97308 0.77460 0.76649 0.05897  -0.05914 -0.08924 506 HOH A O   
6241 O  O   . HOH E .   ? 0.72680 0.68487 0.61111 0.12803  0.04182  -0.07924 507 HOH A O   
6242 O  O   . HOH E .   ? 0.50788 0.66664 0.50867 0.02195  0.07796  0.02046  508 HOH A O   
6243 O  O   . HOH E .   ? 0.69259 0.42797 0.64149 -0.03852 -0.12552 -0.08737 509 HOH A O   
6244 O  O   . HOH E .   ? 0.47700 0.48048 0.55592 0.03319  -0.10858 0.02646  510 HOH A O   
6245 O  O   . HOH E .   ? 0.55621 0.47395 0.63212 -0.06483 0.03449  0.06719  511 HOH A O   
6246 O  O   . HOH E .   ? 0.66929 0.55682 0.74634 -0.07238 -0.07585 -0.01991 512 HOH A O   
6247 O  O   . HOH E .   ? 0.76627 0.63988 0.54355 0.02923  -0.15235 -0.06599 513 HOH A O   
6248 O  O   . HOH E .   ? 0.42700 0.51805 0.45043 0.06166  -0.11245 0.01144  514 HOH A O   
6249 O  O   . HOH E .   ? 0.32503 0.75437 0.67557 0.03374  0.02624  0.05278  515 HOH A O   
6250 O  O   . HOH E .   ? 0.60724 0.46711 0.42613 0.03888  0.03883  0.09153  516 HOH A O   
6251 O  O   . HOH E .   ? 0.63300 0.51192 0.57653 0.12271  -0.01240 -0.01209 517 HOH A O   
6252 O  O   . HOH E .   ? 0.61031 0.41380 0.53202 0.09009  -0.01695 -0.00645 518 HOH A O   
6253 O  O   . HOH E .   ? 0.54613 0.34676 0.49274 0.02054  -0.11867 0.07896  519 HOH A O   
6254 O  O   . HOH E .   ? 0.48307 0.78660 0.61339 -0.00325 0.11201  0.06794  520 HOH A O   
6255 O  O   . HOH E .   ? 0.59672 0.34282 0.51297 0.01488  0.00221  0.07990  521 HOH A O   
6256 O  O   . HOH E .   ? 0.46987 0.37396 0.31860 0.02006  0.07742  0.08980  522 HOH A O   
6257 O  O   . HOH E .   ? 0.60156 0.65792 0.52594 -0.06187 0.04670  0.09883  523 HOH A O   
6258 O  O   . HOH E .   ? 0.67973 0.61506 0.50022 0.04241  -0.02356 -0.00872 524 HOH A O   
6259 O  O   . HOH E .   ? 0.31450 0.35578 0.29902 0.03365  0.00620  0.00119  525 HOH A O   
6260 O  O   . HOH E .   ? 0.57294 0.77391 0.67144 0.05658  0.04287  0.00995  526 HOH A O   
6261 O  O   . HOH E .   ? 0.66801 0.72339 0.73463 -0.14107 0.01377  0.14511  527 HOH A O   
6262 O  O   . HOH E .   ? 0.50670 0.44704 0.56571 -0.05200 -0.05416 -0.01610 528 HOH A O   
6263 O  O   . HOH E .   ? 0.36739 0.40062 0.44471 -0.00479 -0.01097 0.00647  529 HOH A O   
6264 O  O   . HOH E .   ? 0.39029 0.44724 0.41169 0.10178  -0.01213 0.00084  530 HOH A O   
6265 O  O   . HOH E .   ? 0.85734 0.71033 0.75785 0.13388  0.01068  -0.08273 531 HOH A O   
6266 O  O   . HOH E .   ? 0.41743 0.72318 0.56037 0.06114  0.09929  0.02762  532 HOH A O   
6267 O  O   . HOH E .   ? 0.41266 0.77432 0.76221 -0.12197 0.03426  0.12355  533 HOH A O   
6268 O  O   . HOH E .   ? 0.31355 0.30486 0.30279 0.01038  0.01774  -0.00159 534 HOH A O   
6269 O  O   . HOH E .   ? 0.35022 0.35068 0.34470 0.01720  0.03325  -0.00032 535 HOH A O   
6270 O  O   . HOH E .   ? 0.55078 0.57142 0.64157 -0.12420 -0.04307 0.07972  536 HOH A O   
6271 O  O   . HOH E .   ? 0.79284 0.59196 0.68899 0.07087  -0.02094 -0.06412 537 HOH A O   
6272 O  O   . HOH E .   ? 0.50275 0.46810 0.41579 0.01503  0.00424  -0.00981 538 HOH A O   
6273 O  O   . HOH E .   ? 0.46286 0.47625 0.48666 -0.00726 0.07277  0.03954  539 HOH A O   
6274 O  O   . HOH E .   ? 0.30042 0.33123 0.29886 -0.08290 0.01005  0.08663  540 HOH A O   
6275 O  O   . HOH E .   ? 0.62774 0.62571 0.68100 -0.13869 -0.01682 0.12795  541 HOH A O   
6276 O  O   . HOH E .   ? 0.47973 0.77865 0.80707 -0.06073 -0.13758 0.03954  542 HOH A O   
6277 O  O   . HOH E .   ? 0.30764 0.30732 0.28326 -0.07152 -0.00010 0.07591  543 HOH A O   
6278 O  O   . HOH E .   ? 0.48253 0.48055 0.48236 -0.00248 0.05017  0.02129  544 HOH A O   
6279 O  O   . HOH E .   ? 0.54612 0.52898 0.53641 0.00103  -0.07199 0.01711  545 HOH A O   
6280 O  O   . HOH E .   ? 0.37475 0.38343 0.38642 0.00725  0.02963  0.00430  546 HOH A O   
6281 O  O   . HOH E .   ? 0.42569 0.31492 0.43288 -0.04294 -0.06833 -0.03746 547 HOH A O   
6282 O  O   . HOH E .   ? 0.64735 0.54822 0.47918 0.05572  0.00411  0.05244  548 HOH A O   
6283 O  O   . HOH E .   ? 0.41591 0.46899 0.42662 0.08753  0.00209  -0.00388 549 HOH A O   
6284 O  O   . HOH E .   ? 0.62928 0.53996 0.54524 -0.02948 -0.20215 -0.06082 550 HOH A O   
6285 O  O   . HOH E .   ? 0.43324 0.26581 0.39077 -0.00609 -0.06663 0.01287  551 HOH A O   
6286 O  O   . HOH E .   ? 0.61860 0.66325 0.72851 -0.02276 0.01810  0.01890  552 HOH A O   
6287 O  O   . HOH E .   ? 0.68857 0.42375 0.58759 0.05797  -0.01797 0.05890  553 HOH A O   
6288 O  O   . HOH E .   ? 0.43881 0.71012 0.52972 0.08612  0.11132  0.00941  554 HOH A O   
6289 O  O   . HOH E .   ? 0.43004 0.29212 0.36903 0.04265  -0.03303 -0.03380 555 HOH A O   
6290 O  O   . HOH E .   ? 0.45965 0.43498 0.37608 0.02041  0.07518  0.03496  556 HOH A O   
6291 O  O   . HOH E .   ? 0.34121 0.72559 0.69147 -0.06214 0.00556  0.08262  557 HOH A O   
6292 O  O   . HOH E .   ? 0.34941 0.46864 0.33537 0.03839  0.06263  0.00054  558 HOH A O   
6293 O  O   . HOH E .   ? 0.73877 0.57056 0.64396 0.05810  -0.01395 -0.05543 559 HOH A O   
6294 O  O   . HOH E .   ? 0.26323 0.63241 0.56376 -0.04957 0.03749  0.08308  560 HOH A O   
6295 O  O   . HOH E .   ? 0.35054 0.25078 0.32694 0.01916  -0.08120 0.04431  561 HOH A O   
6296 O  O   . HOH E .   ? 0.54246 0.45818 0.56829 0.04916  -0.10006 0.03811  562 HOH A O   
6297 O  O   . HOH E .   ? 0.58486 0.48296 0.50310 0.06765  0.00644  -0.04379 563 HOH A O   
6298 O  O   . HOH E .   ? 0.56974 0.31905 0.52020 -0.01397 0.00590  0.08048  564 HOH A O   
6299 O  O   . HOH E .   ? 0.40268 0.36129 0.30957 0.02988  0.01261  -0.03713 565 HOH A O   
6300 O  O   . HOH E .   ? 0.38889 0.41647 0.36150 0.02399  0.01259  -0.00031 566 HOH A O   
6301 O  O   . HOH E .   ? 0.41912 0.48983 0.38539 -0.07922 0.04605  0.10986  567 HOH A O   
6302 O  O   . HOH E .   ? 0.45091 0.32723 0.36454 0.00402  -0.03819 -0.05671 568 HOH A O   
6303 O  O   . HOH E .   ? 0.44655 0.45345 0.53617 -0.03801 0.01277  0.01990  569 HOH A O   
6304 O  O   . HOH E .   ? 0.78200 0.48538 0.73796 -0.06551 -0.12266 0.08932  570 HOH A O   
6305 O  O   . HOH E .   ? 0.48266 0.57119 0.52112 0.09125  -0.05817 0.01411  571 HOH A O   
6306 O  O   . HOH E .   ? 0.26529 0.27463 0.24732 -0.04305 -0.00213 0.03344  572 HOH A O   
6307 O  O   . HOH E .   ? 0.72823 0.65401 0.60293 -0.07930 -0.01281 0.14273  573 HOH A O   
6308 O  O   . HOH E .   ? 0.34303 0.56373 0.50556 0.03723  -0.03231 0.02026  574 HOH A O   
6309 O  O   . HOH E .   ? 0.28577 0.42158 0.36539 -0.03340 0.00547  0.03360  575 HOH A O   
6310 O  O   . HOH E .   ? 0.61763 0.60910 0.75069 -0.06547 -0.08632 -0.01098 576 HOH A O   
6311 O  O   . HOH E .   ? 0.77055 0.61706 0.66015 0.06216  -0.01142 -0.06735 577 HOH A O   
6312 O  O   . HOH E .   ? 0.51764 0.48643 0.51978 -0.05626 -0.04980 0.01359  578 HOH A O   
6313 O  O   . HOH E .   ? 0.42495 0.45921 0.34828 -0.05084 0.03046  0.07685  579 HOH A O   
6314 O  O   . HOH E .   ? 0.40326 0.71372 0.71005 0.00412  -0.16593 0.02787  580 HOH A O   
6315 O  O   . HOH E .   ? 0.44736 0.41186 0.35724 0.02197  0.02333  0.01251  581 HOH A O   
6316 O  O   . HOH E .   ? 0.55625 0.53498 0.64052 -0.13032 -0.06352 0.07462  582 HOH A O   
6317 O  O   . HOH E .   ? 0.57142 0.61340 0.59099 0.03914  0.08447  0.01134  583 HOH A O   
6318 O  O   . HOH E .   ? 0.40569 0.38457 0.30090 0.00946  0.00533  -0.02266 584 HOH A O   
6319 O  O   . HOH E .   ? 0.59670 0.47812 0.51740 0.12569  -0.04170 0.03583  585 HOH A O   
6320 O  O   . HOH E .   ? 0.29161 0.27923 0.25331 0.01430  0.03449  0.00032  586 HOH A O   
6321 O  O   . HOH E .   ? 0.53294 0.72275 0.67435 0.05857  -0.10081 0.01684  587 HOH A O   
6322 O  O   . HOH E .   ? 0.56042 0.51406 0.43658 -0.00608 -0.06602 -0.01540 588 HOH A O   
6323 O  O   . HOH E .   ? 0.58765 0.52408 0.65342 -0.06577 0.08070  0.11097  589 HOH A O   
6324 O  O   . HOH E .   ? 0.48660 0.53227 0.40719 0.03686  0.04778  -0.01717 590 HOH A O   
6325 O  O   . HOH E .   ? 0.58278 0.63497 0.68315 -0.00364 0.01976  0.01349  591 HOH A O   
6326 O  O   . HOH E .   ? 0.42376 0.38738 0.50561 -0.05203 -0.02216 0.00481  592 HOH A O   
6327 O  O   . HOH E .   ? 0.50578 0.48796 0.40627 0.04765  0.07642  0.00307  593 HOH A O   
6328 O  O   . HOH E .   ? 0.60825 0.53536 0.44053 -0.01711 -0.05763 0.07342  594 HOH A O   
6329 O  O   . HOH E .   ? 0.38409 0.38990 0.33961 0.03364  0.07837  0.01214  595 HOH A O   
6330 O  O   . HOH E .   ? 0.58628 0.42195 0.50501 0.11717  -0.02941 0.02576  596 HOH A O   
6331 O  O   . HOH E .   ? 0.33865 0.36362 0.40528 -0.00787 -0.03027 0.00453  597 HOH A O   
6332 O  O   . HOH E .   ? 0.53995 0.56258 0.71629 -0.06828 -0.11252 -0.00938 598 HOH A O   
6333 O  O   . HOH E .   ? 0.41550 0.30212 0.28672 0.05630  0.00189  0.05139  599 HOH A O   
6334 O  O   . HOH E .   ? 0.30084 0.29114 0.23581 0.02711  0.00120  0.00598  600 HOH A O   
6335 O  O   . HOH E .   ? 0.67983 0.52756 0.57618 0.05330  -0.02941 -0.05483 601 HOH A O   
6336 O  O   . HOH E .   ? 0.33942 0.39546 0.33824 0.06940  -0.04705 0.01205  602 HOH A O   
6337 O  O   . HOH E .   ? 0.37059 0.54909 0.50400 0.01603  -0.07070 0.01633  603 HOH A O   
6338 O  O   . HOH E .   ? 0.48827 0.87149 0.80411 -0.13000 0.10579  0.16217  604 HOH A O   
6339 O  O   . HOH E .   ? 0.62494 0.32712 0.56942 0.01406  -0.03578 0.00955  605 HOH A O   
6340 O  O   . HOH E .   ? 0.87647 0.62592 0.60690 0.06215  -0.10854 -0.11574 606 HOH A O   
6341 O  O   . HOH E .   ? 0.57260 0.52235 0.43518 0.03336  0.03358  0.01665  607 HOH A O   
6342 O  O   . HOH E .   ? 0.62239 0.57044 0.45764 0.04887  -0.03842 0.00601  608 HOH A O   
6343 O  O   . HOH E .   ? 0.29495 0.26336 0.22248 0.01503  0.03220  0.01338  609 HOH A O   
6344 O  O   . HOH E .   ? 0.83497 0.61387 0.61567 0.01147  -0.18470 -0.10428 610 HOH A O   
6345 O  O   . HOH E .   ? 0.63744 0.51844 0.59274 -0.11895 -0.03739 0.15459  611 HOH A O   
6346 O  O   . HOH E .   ? 0.57858 0.44281 0.46759 -0.04422 -0.06274 0.11025  612 HOH A O   
6347 O  O   . HOH E .   ? 0.41965 0.80023 0.66976 0.03405  0.08056  0.05113  613 HOH A O   
6348 O  O   . HOH E .   ? 0.30828 0.29475 0.31439 -0.01113 0.03474  0.01672  614 HOH A O   
6349 O  O   . HOH E .   ? 0.68618 0.72166 0.80654 -0.03550 0.00641  0.01894  615 HOH A O   
6350 O  O   . HOH E .   ? 0.41518 0.40992 0.31604 0.00254  0.00980  -0.00895 616 HOH A O   
6351 O  O   . HOH E .   ? 0.52620 0.40713 0.37355 -0.00285 -0.09589 -0.07339 617 HOH A O   
6352 O  O   . HOH E .   ? 0.44085 0.51136 0.58643 0.03234  -0.00942 0.00889  618 HOH A O   
6353 O  O   . HOH E .   ? 0.75279 0.40309 0.66479 -0.01477 0.00375  0.14637  619 HOH A O   
6354 O  O   . HOH E .   ? 0.69587 0.62681 0.54137 0.04651  0.01982  -0.02547 620 HOH A O   
6355 O  O   . HOH E .   ? 0.28601 0.27271 0.24944 0.00320  0.02549  0.00312  621 HOH A O   
6356 O  O   . HOH E .   ? 0.42301 0.47950 0.51679 0.01497  0.03340  0.01085  622 HOH A O   
6357 O  O   . HOH E .   ? 0.56790 0.49878 0.53286 0.13936  -0.00270 -0.02518 623 HOH A O   
6358 O  O   . HOH E .   ? 0.46937 0.43855 0.48468 0.02095  -0.09232 0.03054  624 HOH A O   
6359 O  O   . HOH E .   ? 0.37499 0.43998 0.46257 -0.05403 -0.19721 -0.01663 625 HOH A O   
6360 O  O   . HOH E .   ? 0.76508 0.64150 0.58509 0.04250  -0.03366 -0.05596 626 HOH A O   
6361 O  O   . HOH E .   ? 0.61321 0.72585 0.66709 0.11056  0.01804  -0.01067 627 HOH A O   
6362 O  O   . HOH E .   ? 0.40022 0.42664 0.48340 0.01221  -0.05567 0.01138  628 HOH A O   
6363 O  O   . HOH E .   ? 0.54102 0.40348 0.54343 -0.08548 -0.09100 0.02696  629 HOH A O   
6364 O  O   . HOH E .   ? 0.67430 0.59518 0.49128 0.03610  0.07405  0.06788  630 HOH A O   
6365 O  O   . HOH E .   ? 0.70961 0.64351 0.54906 0.07582  0.05312  -0.03478 631 HOH A O   
6366 O  O   . HOH E .   ? 0.31732 0.56244 0.52970 -0.10781 0.02622  0.10452  632 HOH A O   
6367 O  O   . HOH E .   ? 0.50880 0.44555 0.35787 0.03439  0.04733  0.03758  633 HOH A O   
6368 O  O   . HOH E .   ? 0.51073 0.71962 0.78998 -0.14184 -0.06644 0.08367  634 HOH A O   
6369 O  O   . HOH E .   ? 0.59884 0.62075 0.46490 -0.05196 0.03670  0.10123  635 HOH A O   
6370 O  O   . HOH E .   ? 0.51897 0.69826 0.59690 0.10112  0.05113  -0.00886 636 HOH A O   
6371 O  O   . HOH E .   ? 0.53345 0.51124 0.53290 -0.11434 -0.00913 0.12253  637 HOH A O   
6372 O  O   . HOH E .   ? 0.49399 0.75821 0.70418 0.09206  -0.04170 0.01859  638 HOH A O   
6373 O  O   . HOH E .   ? 0.82044 0.74371 0.64383 0.06655  -0.02772 0.03680  639 HOH A O   
6374 O  O   . HOH E .   ? 0.62828 0.63302 0.54881 0.08972  0.04342  -0.04863 640 HOH A O   
6375 O  O   . HOH E .   ? 0.62726 0.48029 0.46344 0.06057  -0.01948 -0.09151 641 HOH A O   
6376 O  O   . HOH E .   ? 0.28443 0.38038 0.27270 0.02765  0.04641  0.00126  642 HOH A O   
6377 O  O   . HOH E .   ? 0.60862 0.54650 0.58851 -0.04729 -0.07095 -0.00677 643 HOH A O   
6378 O  O   . HOH E .   ? 0.33630 0.30264 0.26974 -0.00608 -0.05861 0.02271  644 HOH A O   
6379 O  O   . HOH E .   ? 0.25770 0.23820 0.23711 0.00007  -0.00040 0.00250  645 HOH A O   
6380 O  O   . HOH E .   ? 0.43643 0.41231 0.35718 0.01383  0.00551  -0.00399 646 HOH A O   
6381 O  O   . HOH E .   ? 0.49130 0.70870 0.65403 0.07946  -0.04425 0.01595  647 HOH A O   
6382 O  O   . HOH E .   ? 0.45803 0.42936 0.31663 0.06657  -0.08938 0.01263  648 HOH A O   
6383 O  O   . HOH E .   ? 0.41865 0.53890 0.40381 0.01618  0.06081  0.01403  649 HOH A O   
6384 O  O   . HOH E .   ? 0.64290 0.44491 0.63371 -0.08797 -0.10107 0.04600  650 HOH A O   
6385 O  O   . HOH E .   ? 0.41633 0.78259 0.74543 0.07227  -0.07950 0.03314  651 HOH A O   
6386 O  O   . HOH E .   ? 0.70336 0.61268 0.75476 -0.12117 -0.08590 0.05804  652 HOH A O   
6387 O  O   . HOH E .   ? 0.45526 0.50044 0.53945 0.05216  0.03574  -0.00256 653 HOH A O   
6388 O  O   . HOH E .   ? 0.39916 0.41371 0.39929 0.11575  -0.01417 -0.00013 654 HOH A O   
6389 O  O   . HOH E .   ? 0.47812 0.33989 0.35493 -0.00276 -0.07930 -0.07712 655 HOH A O   
6390 O  O   . HOH E .   ? 0.77391 0.59479 0.57684 0.07785  -0.01322 0.09331  656 HOH A O   
6391 O  O   . HOH E .   ? 0.46602 0.26303 0.43341 0.02425  -0.09646 0.04016  657 HOH A O   
6392 O  O   . HOH E .   ? 0.61374 0.53730 0.67833 -0.11883 -0.10774 0.03352  658 HOH A O   
6393 O  O   . HOH E .   ? 0.46285 0.68167 0.57029 -0.09937 0.08975  0.13522  659 HOH A O   
6394 O  O   . HOH E .   ? 0.37153 0.51561 0.47241 0.00313  -0.06817 0.01281  660 HOH A O   
6395 O  O   . HOH E .   ? 0.49609 0.40003 0.51463 0.07913  -0.03342 -0.01816 661 HOH A O   
6396 O  O   . HOH E .   ? 0.41347 0.40826 0.50924 -0.04637 -0.01296 0.00979  662 HOH A O   
6397 O  O   . HOH E .   ? 0.47909 0.67719 0.69455 -0.13663 -0.00134 0.11139  663 HOH A O   
6398 O  O   . HOH E .   ? 0.41956 0.48767 0.44269 0.13240  0.02465  -0.02526 664 HOH A O   
6399 O  O   . HOH E .   ? 0.34350 0.55587 0.53157 -0.12310 0.02957  0.11816  665 HOH A O   
6400 O  O   . HOH E .   ? 0.36179 0.28862 0.34651 -0.05319 -0.05842 0.00854  666 HOH A O   
6401 O  O   . HOH E .   ? 0.57716 0.51606 0.43519 0.04439  0.00362  0.02667  667 HOH A O   
6402 O  O   . HOH E .   ? 0.70271 0.41078 0.66457 -0.06553 -0.12253 0.07230  668 HOH A O   
6403 O  O   . HOH E .   ? 0.40912 0.54753 0.59122 -0.11022 -0.06197 0.05773  669 HOH A O   
6404 O  O   . HOH E .   ? 0.63385 0.43069 0.67453 -0.06384 -0.00892 0.05309  670 HOH A O   
6405 O  O   . HOH E .   ? 0.50340 0.49851 0.45070 0.05898  0.07161  -0.01147 671 HOH A O   
6406 O  O   . HOH E .   ? 0.33492 0.36520 0.28815 -0.04447 0.01919  0.05382  672 HOH A O   
6407 O  O   . HOH E .   ? 0.61545 0.47088 0.52831 0.09002  -0.01026 -0.06254 673 HOH A O   
6408 O  O   . HOH E .   ? 0.54949 0.50309 0.40109 0.01277  -0.01491 -0.03593 674 HOH A O   
6409 O  O   . HOH E .   ? 0.52013 0.36436 0.48689 -0.05088 -0.08439 0.00196  675 HOH A O   
6410 O  O   . HOH E .   ? 0.60483 0.38104 0.44128 0.06161  -0.00335 0.10133  676 HOH A O   
6411 O  O   . HOH E .   ? 0.53105 0.38432 0.40593 0.09821  -0.03193 0.05753  677 HOH A O   
6412 O  O   . HOH E .   ? 0.55063 0.46613 0.43425 -0.01191 -0.09650 -0.05193 678 HOH A O   
6413 O  O   . HOH E .   ? 0.38003 0.38001 0.38579 -0.00497 0.02484  0.00642  679 HOH A O   
6414 O  O   . HOH E .   ? 0.55657 0.37951 0.61319 -0.07224 -0.07541 -0.01972 680 HOH A O   
6415 O  O   . HOH E .   ? 0.62185 0.66054 0.58857 0.14203  0.05044  -0.05337 681 HOH A O   
6416 O  O   . HOH E .   ? 0.32218 0.30137 0.26981 -0.05721 -0.00486 0.06928  682 HOH A O   
6417 O  O   . HOH E .   ? 0.60008 0.50439 0.39383 0.03927  0.07384  0.08109  683 HOH A O   
6418 O  O   . HOH E .   ? 0.50315 0.67261 0.51524 -0.00738 0.07899  0.04462  684 HOH A O   
6419 O  O   . HOH E .   ? 0.38224 0.49001 0.54339 -0.08959 -0.13439 0.01722  685 HOH A O   
6420 O  O   . HOH E .   ? 0.44179 0.79395 0.63893 -0.00299 0.10838  0.07224  686 HOH A O   
6421 O  O   . HOH E .   ? 0.22934 0.22660 0.19063 -0.00677 0.01054  0.00214  687 HOH A O   
6422 O  O   . HOH E .   ? 0.51804 0.47182 0.38096 0.03572  -0.00197 0.00629  688 HOH A O   
6423 O  O   . HOH E .   ? 0.62191 0.45793 0.61203 0.07398  -0.06014 -0.01674 689 HOH A O   
6424 O  O   . HOH E .   ? 0.67283 0.55352 0.56908 0.08474  0.00659  -0.05994 690 HOH A O   
6425 O  O   . HOH E .   ? 0.33322 0.26741 0.33060 -0.07541 -0.04356 0.04992  691 HOH A O   
6426 O  O   . HOH E .   ? 0.48750 0.41108 0.39343 0.04833  0.00883  -0.04788 692 HOH A O   
6427 O  O   . HOH E .   ? 0.35500 0.41035 0.35197 -0.09177 0.02788  0.10823  693 HOH A O   
6428 O  O   . HOH E .   ? 0.33111 0.26632 0.25087 -0.00029 -0.02271 -0.03753 694 HOH A O   
6429 O  O   . HOH E .   ? 0.56113 0.49375 0.43602 0.02996  -0.00100 -0.02668 695 HOH A O   
6430 O  O   . HOH E .   ? 0.68779 0.56021 0.57321 0.03595  -0.02765 -0.04857 696 HOH A O   
6431 O  O   . HOH E .   ? 0.48151 0.66936 0.68192 -0.03766 -0.19581 0.00702  697 HOH A O   
6432 O  O   . HOH E .   ? 0.32126 0.30048 0.27903 0.00541  0.03505  0.01095  698 HOH A O   
6433 O  O   . HOH E .   ? 0.54466 0.57190 0.51638 0.02886  0.10936  0.03614  699 HOH A O   
6434 O  O   . HOH E .   ? 0.48694 0.52419 0.42578 0.07464  0.04812  -0.03454 700 HOH A O   
6435 O  O   . HOH E .   ? 0.55424 0.35380 0.48284 0.03674  -0.02026 -0.02903 701 HOH A O   
6436 O  O   . HOH E .   ? 0.25890 0.27799 0.31012 0.00262  -0.01072 0.00521  702 HOH A O   
6437 O  O   . HOH E .   ? 0.38239 0.65286 0.70041 -0.08523 -0.13844 0.04142  703 HOH A O   
6438 O  O   . HOH E .   ? 0.67001 0.48560 0.57072 -0.02511 0.07914  0.15636  704 HOH A O   
6439 O  O   . HOH E .   ? 0.40718 0.68926 0.67257 -0.11502 0.01923  0.10858  705 HOH A O   
6440 O  O   . HOH E .   ? 0.36914 0.28257 0.31916 0.01448  0.01514  0.00768  706 HOH A O   
6441 O  O   . HOH E .   ? 0.66420 0.60725 0.48386 0.08856  -0.09492 0.03086  707 HOH A O   
6442 O  O   . HOH E .   ? 0.51109 0.39882 0.45198 0.12368  -0.02581 0.01330  708 HOH A O   
6443 O  O   . HOH E .   ? 0.58371 0.50255 0.41742 0.02084  -0.12347 -0.04486 709 HOH A O   
6444 O  O   . HOH E .   ? 0.63700 0.58626 0.58030 0.07300  0.03580  -0.03543 710 HOH A O   
6445 O  O   . HOH E .   ? 0.53448 0.56293 0.63058 -0.11620 -0.05200 0.06426  711 HOH A O   
6446 O  O   . HOH E .   ? 0.69662 0.56420 0.58145 0.00169  -0.07283 -0.04883 712 HOH A O   
6447 O  O   . HOH E .   ? 0.61775 0.52602 0.50251 0.03875  -0.00439 -0.03930 713 HOH A O   
6448 O  O   . HOH E .   ? 0.45836 0.33574 0.33404 0.02753  -0.02622 -0.06856 714 HOH A O   
6449 O  O   . HOH E .   ? 0.50271 0.69004 0.48505 0.05924  0.10841  0.00731  715 HOH A O   
6450 O  O   . HOH E .   ? 0.48557 0.53127 0.38210 -0.01274 0.04033  0.03234  716 HOH A O   
6451 O  O   . HOH E .   ? 0.59380 0.57502 0.59795 0.00817  -0.07988 0.02204  717 HOH A O   
6452 O  O   . HOH E .   ? 0.37745 0.39592 0.30982 0.05504  0.03840  -0.02973 718 HOH A O   
6453 O  O   . HOH E .   ? 0.60478 0.73196 0.59065 -0.04109 0.06582  0.06953  719 HOH A O   
6454 O  O   . HOH E .   ? 0.40550 0.46624 0.41192 0.01037  -0.16224 -0.01136 720 HOH A O   
6455 O  O   . HOH E .   ? 0.45631 0.40663 0.42416 0.07030  0.02549  -0.03211 721 HOH A O   
6456 O  O   . HOH E .   ? 0.27587 0.28580 0.20336 -0.00584 0.01546  0.00410  722 HOH A O   
6457 O  O   . HOH E .   ? 0.39107 0.36650 0.30888 0.05830  -0.02259 0.01873  723 HOH A O   
6458 O  O   . HOH E .   ? 0.54885 0.44213 0.58374 -0.10668 -0.09627 0.03578  724 HOH A O   
6459 O  O   . HOH E .   ? 0.44331 0.48689 0.43641 0.14485  0.03821  -0.04309 725 HOH A O   
6460 O  O   . HOH E .   ? 0.58408 0.42156 0.47572 0.11525  -0.03932 0.05158  726 HOH A O   
6461 O  O   . HOH E .   ? 0.42622 0.65807 0.74166 -0.12392 -0.13092 0.05213  727 HOH A O   
6462 O  O   . HOH E .   ? 0.31517 0.30769 0.29101 0.00581  0.03160  0.00401  728 HOH A O   
6463 O  O   . HOH E .   ? 0.48103 0.50244 0.47294 0.10571  -0.03886 0.01452  729 HOH A O   
6464 O  O   . HOH E .   ? 0.43893 0.40505 0.31103 0.07238  -0.06412 0.02372  730 HOH A O   
6465 O  O   . HOH E .   ? 0.31501 0.34843 0.42466 -0.02912 -0.04488 0.00230  731 HOH A O   
6466 O  O   . HOH E .   ? 0.63722 0.53734 0.48236 0.01921  -0.06629 -0.04609 732 HOH A O   
6467 O  O   . HOH E .   ? 0.63100 0.38888 0.57700 -0.09557 -0.09447 0.13814  733 HOH A O   
6468 O  O   . HOH E .   ? 0.25327 0.25246 0.20206 0.01922  0.00758  0.00272  734 HOH A O   
6469 O  O   . HOH E .   ? 0.57453 0.53684 0.57187 -0.05473 -0.17935 -0.03633 735 HOH A O   
6470 O  O   . HOH E .   ? 0.63841 0.86523 0.82069 0.06921  -0.09991 0.02006  736 HOH A O   
6471 O  O   . HOH E .   ? 0.51388 0.46821 0.44414 -0.01523 -0.07665 -0.02647 737 HOH A O   
6472 O  O   . HOH E .   ? 0.59630 0.67311 0.51502 -0.01487 0.05538  0.04013  738 HOH A O   
6473 O  O   . HOH E .   ? 0.34229 0.66447 0.71578 -0.11839 -0.07054 0.07979  739 HOH A O   
6474 O  O   . HOH E .   ? 0.33486 0.36191 0.37761 0.01196  0.03439  0.00680  740 HOH A O   
6475 O  O   . HOH E .   ? 0.44513 0.50515 0.60935 0.04868  -0.06157 0.01429  741 HOH A O   
6476 O  O   . HOH E .   ? 0.50318 0.59431 0.44502 0.02231  0.06172  0.00505  742 HOH A O   
6477 O  O   . HOH E .   ? 0.54108 0.50428 0.47795 0.09610  -0.03785 0.02593  743 HOH A O   
6478 O  O   . HOH E .   ? 0.64703 0.66440 0.72200 -0.02658 0.03929  0.02898  744 HOH A O   
6479 O  O   . HOH E .   ? 0.58894 0.72021 0.56905 -0.07894 0.08276  0.12619  745 HOH A O   
6480 O  O   . HOH E .   ? 0.46113 0.51944 0.64676 0.08474  -0.04820 0.00821  746 HOH A O   
6481 O  O   . HOH E .   ? 0.44863 0.46139 0.51528 -0.02455 -0.08848 -0.00678 747 HOH A O   
6482 O  O   . HOH E .   ? 0.60573 0.52675 0.59432 -0.05944 -0.08955 -0.00773 748 HOH A O   
6483 O  O   . HOH E .   ? 0.61804 0.57870 0.48881 -0.00879 -0.04946 0.02381  749 HOH A O   
6484 O  O   . HOH E .   ? 0.49766 0.45036 0.63712 -0.08273 0.01137  0.05288  750 HOH A O   
6485 O  O   . HOH E .   ? 0.44886 0.35190 0.37572 -0.00277 -0.04006 -0.02454 751 HOH A O   
6486 O  O   . HOH E .   ? 0.41616 0.42742 0.32874 0.00419  0.02133  -0.00476 752 HOH A O   
6487 O  O   . HOH E .   ? 0.41870 0.43011 0.45517 -0.01085 0.03474  0.01585  753 HOH A O   
6488 O  O   . HOH E .   ? 0.48078 0.57057 0.59203 -0.05063 -0.21878 -0.01636 754 HOH A O   
6489 O  O   . HOH E .   ? 0.41501 0.34637 0.47056 -0.05419 0.05282  0.07534  755 HOH A O   
6490 O  O   . HOH E .   ? 0.41654 0.37757 0.30306 -0.00411 -0.03682 -0.01903 756 HOH A O   
6491 O  O   . HOH E .   ? 0.73523 0.39498 0.66405 -0.00341 -0.01378 0.09914  757 HOH A O   
6492 O  O   . HOH E .   ? 0.72950 0.71061 0.57966 -0.06567 0.01854  0.12884  758 HOH A O   
6493 O  O   . HOH E .   ? 0.44152 0.72715 0.54221 0.01796  0.11345  0.05170  759 HOH A O   
6494 O  O   . HOH E .   ? 0.68925 0.71828 0.77692 0.09761  0.03645  -0.01950 760 HOH A O   
6495 O  O   . HOH E .   ? 0.41038 0.46255 0.50257 -0.13320 -0.01318 0.11002  761 HOH A O   
6496 O  O   . HOH E .   ? 0.54012 0.35318 0.49493 -0.02532 -0.07861 0.00812  762 HOH A O   
6497 O  O   . HOH E .   ? 0.41720 0.53498 0.58399 -0.09381 -0.10669 0.02910  763 HOH A O   
6498 O  O   . HOH E .   ? 0.35512 0.60637 0.67940 -0.12922 -0.09633 0.06887  764 HOH A O   
6499 O  O   . HOH E .   ? 0.76211 0.62687 0.76273 -0.13757 -0.05581 0.14582  765 HOH A O   
6500 O  O   . HOH E .   ? 0.67844 0.57034 0.54959 -0.04493 -0.04910 0.10959  766 HOH A O   
6501 O  O   . HOH E .   ? 0.44086 0.64176 0.43779 0.08889  0.11597  -0.00696 767 HOH A O   
6502 O  O   . HOH E .   ? 0.73197 0.74017 0.86958 -0.06403 0.04847  0.06343  768 HOH A O   
6503 O  O   . HOH E .   ? 0.88548 0.56980 0.80119 -0.00718 -0.10619 -0.09122 769 HOH A O   
6504 O  O   . HOH E .   ? 0.70777 0.60440 0.63659 0.11173  0.00679  -0.04627 770 HOH A O   
6505 O  O   . HOH E .   ? 0.73396 0.60240 0.53231 0.05626  0.01619  0.07773  771 HOH A O   
6506 O  O   . HOH E .   ? 0.63043 0.73500 0.66273 0.06853  -0.17052 0.01097  772 HOH A O   
6507 O  O   . HOH E .   ? 0.59107 0.51433 0.61800 -0.12377 -0.04914 0.10231  773 HOH A O   
6508 O  O   . HOH E .   ? 0.51696 0.64505 0.58683 0.08897  -0.00276 0.00170  774 HOH A O   
6509 O  O   . HOH E .   ? 0.51093 0.53618 0.50038 0.02539  0.08857  0.02376  775 HOH A O   
6510 O  O   . HOH E .   ? 0.53871 0.57914 0.60702 0.00207  0.03798  0.01401  776 HOH A O   
6511 O  O   . HOH E .   ? 0.44704 0.36138 0.51264 -0.06552 -0.09927 -0.03382 777 HOH A O   
6512 O  O   . HOH E .   ? 0.61312 0.72446 0.76889 -0.12310 -0.03748 0.07791  778 HOH A O   
6513 O  O   . HOH E .   ? 0.52498 0.47374 0.41300 0.02232  -0.00203 -0.01762 779 HOH A O   
6514 O  O   . HOH E .   ? 0.53639 0.49921 0.43065 0.02508  0.02975  0.00713  780 HOH A O   
6515 O  O   . HOH E .   ? 0.47648 0.45923 0.38340 -0.08568 0.01479  0.13399  781 HOH A O   
6516 O  O   . HOH E .   ? 0.51715 0.48558 0.37073 -0.00362 -0.02901 0.00116  782 HOH A O   
6517 O  O   . HOH E .   ? 0.46681 0.59037 0.66255 -0.09567 -0.18688 0.00782  783 HOH A O   
6518 O  O   . HOH E .   ? 0.68451 0.62192 0.50810 0.08083  -0.06937 0.03222  784 HOH A O   
6519 O  O   . HOH E .   ? 0.62010 0.58522 0.73487 -0.07010 0.04266  0.06871  785 HOH A O   
6520 O  O   . HOH E .   ? 0.48447 0.45315 0.37690 0.05251  -0.02692 0.01777  786 HOH A O   
6521 O  O   . HOH E .   ? 0.51099 0.61070 0.61683 -0.14236 0.01858  0.13925  787 HOH A O   
6522 O  O   . HOH E .   ? 0.62388 0.60174 0.53153 0.06191  0.07113  -0.01435 788 HOH A O   
6523 O  O   . HOH E .   ? 0.74055 0.52238 0.54405 0.06264  0.00227  0.11502  789 HOH A O   
6524 O  O   . HOH E .   ? 0.68195 0.51841 0.68387 -0.11407 -0.07988 0.09446  790 HOH A O   
6525 O  O   . HOH E .   ? 0.53839 0.50273 0.50971 -0.01414 0.09626  0.08333  791 HOH A O   
6526 O  O   . HOH E .   ? 0.60098 0.50042 0.48460 0.00889  -0.03824 -0.05944 792 HOH A O   
6527 O  O   . HOH E .   ? 0.47581 0.43383 0.50510 0.03352  -0.09681 0.03389  793 HOH A O   
6528 O  O   . HOH E .   ? 0.70780 0.43184 0.61908 0.05784  -0.02355 0.03861  794 HOH A O   
6529 O  O   . HOH E .   ? 0.37285 0.38708 0.32545 -0.05736 0.01233  0.06992  795 HOH A O   
6530 O  O   . HOH E .   ? 0.49753 0.84890 0.87473 -0.06288 -0.11087 0.05191  796 HOH A O   
6531 O  O   . HOH E .   ? 0.78895 0.60671 0.85324 -0.09709 0.05029  0.14171  797 HOH A O   
6532 O  O   . HOH E .   ? 0.59634 0.55247 0.54904 0.11184  -0.03498 0.02140  798 HOH A O   
6533 O  O   . HOH E .   ? 0.60823 0.52321 0.63083 0.10890  -0.01180 -0.03626 799 HOH A O   
6534 O  O   . HOH E .   ? 0.43385 0.84029 0.82011 0.06280  -0.11237 0.03662  800 HOH A O   
6535 O  O   . HOH E .   ? 0.64555 0.66925 0.54049 0.01624  0.03428  -0.00921 801 HOH A O   
6536 O  O   . HOH E .   ? 0.65118 0.66591 0.67159 0.00279  0.04123  0.01154  802 HOH A O   
6537 O  O   . HOH E .   ? 0.29222 0.23158 0.22974 -0.00087 -0.07037 0.04328  803 HOH A O   
6538 O  O   . HOH E .   ? 0.62318 0.65484 0.76617 -0.04808 -0.03026 0.01011  804 HOH A O   
6539 O  O   . HOH E .   ? 0.40492 0.38566 0.32614 0.05470  0.02742  -0.03685 805 HOH A O   
6540 O  O   . HOH E .   ? 0.76682 0.55763 0.79738 -0.08585 0.05009  0.14813  806 HOH A O   
6541 O  O   . HOH E .   ? 0.76219 0.87028 0.80451 0.05036  -0.16017 0.00650  807 HOH A O   
6542 O  O   . HOH E .   ? 0.50507 0.76106 0.62071 -0.07836 0.10671  0.12393  808 HOH A O   
6543 O  O   . HOH E .   ? 0.59956 0.61104 0.64219 -0.01504 0.05048  0.02869  809 HOH A O   
6544 O  O   . HOH E .   ? 0.83185 0.66008 0.74476 0.09824  -0.00894 -0.04776 810 HOH A O   
6545 O  O   . HOH E .   ? 0.59679 0.55134 0.47115 0.06860  -0.04125 0.02760  811 HOH A O   
6546 O  O   . HOH E .   ? 0.59311 0.57838 0.63040 0.02338  -0.10604 0.02845  812 HOH A O   
6547 O  O   . HOH E .   ? 0.73787 0.67430 0.65463 0.07928  0.01880  -0.04896 813 HOH A O   
6548 O  O   . HOH E .   ? 0.77849 0.71428 0.60341 0.04173  -0.00221 -0.00686 814 HOH A O   
6549 O  O   . HOH E .   ? 0.73503 0.69141 0.60240 0.11347  0.04060  -0.07867 815 HOH A O   
6550 O  O   . HOH E .   ? 0.50740 0.34673 0.39123 0.00035  -0.07448 -0.08118 816 HOH A O   
6551 O  O   . HOH E .   ? 0.60910 0.81122 0.65013 -0.03707 0.09039  0.07832  817 HOH A O   
6552 O  O   . HOH E .   ? 0.58260 0.48630 0.63467 -0.05974 -0.07803 -0.02893 818 HOH A O   
6553 O  O   . HOH E .   ? 0.61169 0.56654 0.51564 0.07032  -0.02726 0.02737  819 HOH A O   
6554 O  O   . HOH E .   ? 0.62214 0.55005 0.49203 0.02764  -0.00736 -0.05417 820 HOH A O   
6555 O  O   . HOH E .   ? 0.65378 0.47688 0.61702 -0.05608 -0.10476 -0.01088 821 HOH A O   
6556 O  O   . HOH E .   ? 0.65699 0.61777 0.55301 -0.00712 -0.06273 0.02147  822 HOH A O   
6557 O  O   . HOH E .   ? 0.67888 0.63100 0.55354 0.04993  -0.01430 0.02208  823 HOH A O   
6558 O  O   . HOH E .   ? 0.56624 0.78405 0.66569 0.12342  0.06880  -0.01239 824 HOH A O   
6559 O  O   . HOH E .   ? 0.73130 0.63670 0.66324 -0.11063 -0.02186 0.15828  825 HOH A O   
6560 O  O   . HOH E .   ? 0.55947 0.60091 0.66188 -0.01066 -0.04284 0.00586  826 HOH A O   
6561 O  O   . HOH E .   ? 0.71868 0.68543 0.66624 -0.01478 -0.09788 -0.01541 827 HOH A O   
6562 O  O   . HOH E .   ? 0.82805 0.66706 0.79306 -0.12840 -0.05534 0.16315  828 HOH A O   
6563 O  O   . HOH E .   ? 0.78247 0.70499 0.63337 0.05744  -0.00808 0.03871  829 HOH A O   
6564 O  O   . HOH E .   ? 0.72173 0.80216 0.63204 -0.03350 0.06109  0.06934  830 HOH A O   
6565 O  O   . HOH E .   ? 0.57942 0.75379 0.71361 0.02681  -0.14511 0.01109  831 HOH A O   
6566 O  O   . HOH E .   ? 0.72542 0.59881 0.56287 0.05735  0.00525  0.06615  832 HOH A O   
6567 O  O   . HOH E .   ? 0.59964 0.76287 0.85069 -0.11044 -0.18158 0.02092  833 HOH A O   
6568 O  O   . HOH E .   ? 0.51815 0.53530 0.53319 0.15244  -0.00128 -0.01881 834 HOH A O   
6569 O  O   . HOH E .   ? 0.62959 0.75477 0.64925 -0.11002 0.07581  0.15313  835 HOH A O   
6570 O  O   . HOH E .   ? 0.48652 0.42226 0.37202 0.01264  -0.01600 -0.04473 836 HOH A O   
6571 O  O   . HOH E .   ? 0.36053 0.35204 0.35554 -0.00496 0.03143  0.01008  837 HOH A O   
6572 O  O   . HOH E .   ? 0.68337 0.50530 0.66858 0.04268  -0.09395 0.03251  838 HOH A O   
6573 O  O   . HOH E .   ? 0.65362 0.64165 0.53742 0.03180  0.02410  -0.03312 839 HOH A O   
6574 O  O   . HOH E .   ? 0.51992 0.57490 0.63615 0.05643  0.01913  -0.00052 840 HOH A O   
6575 O  O   . HOH E .   ? 0.44069 0.44406 0.44197 0.00268  0.03352  0.00704  841 HOH A O   
6576 O  O   . HOH E .   ? 0.49351 0.69990 0.53361 -0.01756 0.09124  0.06154  842 HOH A O   
6577 O  O   . HOH E .   ? 0.52950 0.55905 0.51815 -0.10744 0.02176  0.13035  843 HOH A O   
6578 O  O   . HOH E .   ? 0.61671 0.55598 0.52766 0.08231  -0.02738 0.03080  844 HOH A O   
6579 O  O   . HOH E .   ? 0.71436 0.49253 0.62676 0.05808  -0.02551 -0.04528 845 HOH A O   
6580 O  O   . HOH E .   ? 0.65536 0.74302 0.57323 -0.04874 0.06623  0.09124  846 HOH A O   
6581 O  O   . HOH E .   ? 0.70547 0.47024 0.64581 0.01853  -0.03086 -0.02169 847 HOH A O   
6582 O  O   . HOH E .   ? 0.67000 0.67541 0.54896 0.02711  0.03030  -0.02388 848 HOH A O   
6583 O  O   . HOH E .   ? 0.55904 0.79937 0.76775 0.03429  -0.13886 0.01994  849 HOH A O   
6584 O  O   . HOH E .   ? 0.81290 0.56961 0.80580 -0.10656 -0.11277 0.08389  850 HOH A O   
6585 O  O   . HOH E .   ? 0.70237 0.85537 0.67831 0.00637  0.08464  0.03448  851 HOH A O   
6586 O  O   . HOH E .   ? 0.50409 0.61117 0.67971 -0.11337 -0.09800 0.04177  852 HOH A O   
6587 O  O   . HOH E .   ? 0.42195 0.48502 0.57186 0.03383  -0.04015 0.01136  853 HOH A O   
6588 O  O   . HOH E .   ? 0.55844 0.51318 0.43079 0.01603  -0.00553 -0.03834 854 HOH A O   
6589 O  O   . HOH E .   ? 0.82673 0.71977 0.63667 0.03393  -0.05786 -0.04791 855 HOH A O   
6590 O  O   . HOH E .   ? 0.58541 0.54711 0.48919 0.04529  0.01978  -0.04219 856 HOH A O   
6591 O  O   . HOH E .   ? 0.58793 0.82353 0.62164 -0.00082 0.11538  0.06103  857 HOH A O   
6592 O  O   . HOH E .   ? 0.68949 0.58870 0.54095 0.03391  -0.01839 -0.06925 858 HOH A O   
6593 O  O   . HOH E .   ? 0.60362 0.56514 0.51724 0.07178  0.02583  -0.04736 859 HOH A O   
6594 O  O   . HOH E .   ? 0.44484 0.50334 0.58504 0.02118  -0.05478 0.01246  860 HOH A O   
6595 O  O   . HOH E .   ? 0.93691 0.71333 0.66731 0.03710  -0.16137 -0.10758 861 HOH A O   
6596 O  O   . HOH E .   ? 0.55774 0.51556 0.41248 -0.00146 -0.04161 -0.01434 862 HOH A O   
6597 O  O   . HOH E .   ? 0.68117 0.72130 0.57578 -0.06686 0.04655  0.11671  863 HOH A O   
6598 O  O   . HOH E .   ? 0.64725 0.45228 0.59745 -0.00016 -0.07522 -0.00112 864 HOH A O   
6599 O  O   . HOH E .   ? 0.70033 0.76115 0.83722 -0.01354 -0.02960 0.00973  865 HOH A O   
6600 O  O   . HOH E .   ? 0.56254 0.51512 0.43849 0.03538  0.01009  -0.04740 866 HOH A O   
6601 O  O   . HOH E .   ? 0.57498 0.60797 0.46176 -0.04174 0.03642  0.07726  867 HOH A O   
6602 O  O   . HOH E .   ? 0.66733 0.58510 0.51052 -0.01079 -0.07602 0.07216  868 HOH A O   
6603 O  O   . HOH E .   ? 0.68470 0.52313 0.61606 0.00905  -0.05732 -0.02673 869 HOH A O   
6604 O  O   . HOH E .   ? 0.52158 0.75767 0.67263 -0.11814 0.08640  0.14827  870 HOH A O   
6605 O  O   . HOH E .   ? 0.79266 0.67841 0.68285 0.06565  0.00167  -0.06358 871 HOH A O   
6606 O  O   . HOH E .   ? 0.65431 0.84655 0.88081 -0.05936 -0.19894 0.00894  872 HOH A O   
6607 O  O   . HOH E .   ? 0.54435 0.58689 0.69241 -0.04248 -0.04223 0.00712  873 HOH A O   
6608 O  O   . HOH E .   ? 0.67288 0.61247 0.52267 0.03755  0.02602  0.02526  874 HOH A O   
6609 O  O   . HOH E .   ? 0.83540 0.62707 0.75660 0.11968  -0.02310 -0.01750 875 HOH A O   
6610 O  O   . HOH E .   ? 0.58847 0.69007 0.64595 0.11084  -0.00771 -0.00127 876 HOH A O   
6611 O  O   . HOH E .   ? 0.59219 0.35527 0.53350 0.03096  -0.14152 0.09324  877 HOH A O   
6612 O  O   . HOH E .   ? 0.64804 0.70325 0.62888 0.03358  -0.15292 -0.00501 878 HOH A O   
6613 O  O   . HOH E .   ? 0.57384 0.59918 0.64286 -0.06640 -0.20689 -0.02540 879 HOH A O   
6614 O  O   . HOH E .   ? 0.56599 0.43258 0.45076 0.00964  -0.04862 -0.07012 880 HOH A O   
6615 O  O   . HOH E .   ? 0.43764 0.42604 0.41110 0.00253  0.03330  0.00774  881 HOH A O   
6616 O  O   . HOH E .   ? 0.65647 0.59872 0.51049 0.03970  0.01173  0.02149  882 HOH A O   
6617 O  O   . HOH E .   ? 0.69237 0.57595 0.56687 0.09942  -0.03850 0.05340  883 HOH A O   
6618 O  O   . HOH E .   ? 0.60283 0.61798 0.74386 -0.05674 -0.02270 0.01423  884 HOH A O   
6619 O  O   . HOH E .   ? 0.49955 0.64852 0.51857 -0.09469 0.08511  0.13925  885 HOH A O   
6620 O  O   . HOH E .   ? 0.61741 0.68263 0.56829 -0.09078 0.05219  0.13408  886 HOH A O   
6621 O  O   . HOH E .   ? 0.81998 0.50466 0.79583 -0.03583 -0.01427 0.08470  887 HOH A O   
6622 O  O   . HOH E .   ? 0.53685 0.51130 0.48383 -0.00483 0.11768  0.09348  888 HOH A O   
6623 O  O   . HOH E .   ? 0.65530 0.53380 0.60301 0.13650  -0.02193 -0.00223 889 HOH A O   
6624 O  O   . HOH E .   ? 0.51596 0.53282 0.59480 0.01891  -0.09930 0.01930  890 HOH A O   
6625 O  O   . HOH E .   ? 0.94806 1.09198 1.03243 0.10401  0.00430  -0.00138 891 HOH A O   
6626 O  O   . HOH E .   ? 0.70496 0.75282 0.57217 -0.01316 0.04756  0.04298  892 HOH A O   
6627 O  O   . HOH E .   ? 0.66550 0.49124 0.58753 0.03622  -0.01824 -0.04193 893 HOH A O   
6628 O  O   . HOH E .   ? 0.62947 0.53312 0.50721 0.08365  -0.02753 0.04582  894 HOH A O   
6629 O  O   . HOH E .   ? 0.49615 0.81075 0.62847 0.04192  0.11720  0.04171  895 HOH A O   
6630 O  O   . HOH E .   ? 0.50920 0.53468 0.52767 0.13999  -0.01244 -0.00689 896 HOH A O   
6631 O  O   . HOH E .   ? 0.71123 0.64255 0.74436 -0.14010 -0.04099 0.12795  897 HOH A O   
6632 O  O   . HOH E .   ? 0.54172 0.37453 0.47176 0.02885  -0.05135 -0.03339 898 HOH A O   
6633 O  O   . HOH E .   ? 0.67849 0.72300 0.69198 0.11906  -0.05614 0.01758  899 HOH A O   
6634 O  O   . HOH E .   ? 0.55970 0.58146 0.47523 0.04811  0.04151  -0.02928 900 HOH A O   
6635 O  O   . HOH E .   ? 0.89618 0.57918 0.77108 0.01286  -0.10929 -0.11345 901 HOH A O   
6636 O  O   . HOH E .   ? 0.65545 0.56877 0.60765 0.14608  0.00302  -0.04114 902 HOH A O   
6637 O  O   . HOH E .   ? 0.60689 0.61096 0.53555 0.04772  0.09377  0.01154  903 HOH A O   
6638 O  O   . HOH E .   ? 0.83305 0.83931 0.66519 -0.06259 0.04013  0.13418  904 HOH A O   
6639 O  O   . HOH E .   ? 0.67892 0.61476 0.56694 -0.01068 -0.08965 -0.03646 905 HOH A O   
6640 O  O   . HOH E .   ? 0.72658 0.77633 0.59986 -0.02763 0.04868  0.06397  906 HOH A O   
6641 O  O   . HOH E .   ? 0.82115 0.67617 0.55177 0.04606  -0.13846 -0.06863 907 HOH A O   
6642 O  O   . HOH E .   ? 0.42725 0.63931 0.62855 -0.14048 0.03567  0.13688  908 HOH A O   
6643 O  O   . HOH E .   ? 0.53116 0.52789 0.51814 0.11778  -0.02920 0.01025  909 HOH A O   
6644 O  O   . HOH E .   ? 0.65093 0.61530 0.75242 -0.14118 -0.08736 0.06703  910 HOH A O   
6645 O  O   . HOH E .   ? 0.66755 0.63890 0.54137 0.06441  0.07896  -0.00936 911 HOH A O   
6646 O  O   . HOH E .   ? 0.57043 0.46500 0.42996 0.06901  -0.01282 0.05101  912 HOH A O   
6647 O  O   . HOH E .   ? 0.70978 0.66256 0.63185 -0.01459 -0.11018 -0.02396 913 HOH A O   
6648 O  O   . HOH E .   ? 0.72292 0.59926 0.74241 -0.12197 -0.06936 0.09481  914 HOH A O   
6649 O  O   . HOH E .   ? 0.44960 0.81562 0.66036 0.03424  0.10473  0.05184  915 HOH A O   
6650 O  O   . HOH E .   ? 0.63280 0.55753 0.50290 0.06514  -0.01672 0.03813  916 HOH A O   
6651 O  O   . HOH E .   ? 0.70538 0.67484 0.70683 -0.02945 -0.12754 -0.02752 917 HOH A O   
6652 O  O   . HOH E .   ? 0.56825 0.48197 0.68243 -0.08584 -0.11410 -0.02832 918 HOH A O   
6653 O  O   . HOH E .   ? 0.75117 0.66016 0.64778 0.11412  -0.05309 0.04673  919 HOH A O   
6654 O  O   . HOH E .   ? 0.57458 0.77653 0.74526 0.02625  -0.18322 0.01172  920 HOH A O   
6655 O  O   . HOH E .   ? 0.65080 0.79184 0.90662 -0.12498 -0.20422 0.01602  921 HOH A O   
6656 O  O   . HOH E .   ? 0.76865 0.78165 0.61767 0.00243  0.02528  0.01098  922 HOH A O   
6657 O  O   . HOH E .   ? 0.60166 0.62503 0.68615 0.01400  -0.12198 0.01806  923 HOH A O   
6658 O  O   . HOH E .   ? 0.72737 0.70986 0.77882 -0.08171 -0.12442 -0.00323 924 HOH A O   
6659 O  O   . HOH E .   ? 0.76928 0.78306 0.86042 -0.09464 -0.13259 0.00545  925 HOH A O   
# 
