data_8RXV
# 
_entry.id   8RXV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8RXV         pdb_00008rxv 10.2210/pdb8rxv/pdb 
WWPDB D_1292136476 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8RXV 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              guichou@cbs.cnrs.fr 
_pdbx_contact_author.name_first         jean-francois 
_pdbx_contact_author.name_last          guichou 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7699-3235 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Guichou, J.F.' 1 ? 
'Gelin, M.'     2 ? 
'Allemand, F.'  3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'TEAD2 with an inhibitor' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Guichou, J.F.' 1 ? 
primary 'Gelin, M.'     2 ? 
primary 'Allemand, F.'  3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Transcriptional enhancer factor TEF-4'                              27489.096 2 ? ? ? ? 
2 non-polymer syn '~{N}-[2-(5-phenylmethoxy-1~{H}-indol-3-yl)ethyl]methanesulfonamide' 344.428   2 ? ? ? ? 
3 water       nat water                                                                18.015    4 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'TEA domain family member 2,TEAD-2' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPH
AFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLL
RSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRDVEHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPH
AFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLL
RSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRDVEHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '~{N}-[2-(5-phenylmethoxy-1~{H}-indol-3-yl)ethyl]methanesulfonamide' A1H3W 
3 water                                                                HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   TRP n 
1 4   GLN n 
1 5   ALA n 
1 6   ARG n 
1 7   GLY n 
1 8   LEU n 
1 9   GLY n 
1 10  THR n 
1 11  ALA n 
1 12  ARG n 
1 13  LEU n 
1 14  GLN n 
1 15  LEU n 
1 16  VAL n 
1 17  GLU n 
1 18  PHE n 
1 19  SER n 
1 20  ALA n 
1 21  PHE n 
1 22  VAL n 
1 23  GLU n 
1 24  PRO n 
1 25  PRO n 
1 26  ASP n 
1 27  ALA n 
1 28  VAL n 
1 29  ASP n 
1 30  SER n 
1 31  TYR n 
1 32  GLN n 
1 33  ARG n 
1 34  HIS n 
1 35  LEU n 
1 36  PHE n 
1 37  VAL n 
1 38  HIS n 
1 39  ILE n 
1 40  SER n 
1 41  GLN n 
1 42  HIS n 
1 43  CYS n 
1 44  PRO n 
1 45  SER n 
1 46  PRO n 
1 47  GLY n 
1 48  ALA n 
1 49  PRO n 
1 50  PRO n 
1 51  LEU n 
1 52  GLU n 
1 53  SER n 
1 54  VAL n 
1 55  ASP n 
1 56  VAL n 
1 57  ARG n 
1 58  GLN n 
1 59  ILE n 
1 60  TYR n 
1 61  ASP n 
1 62  LYS n 
1 63  PHE n 
1 64  PRO n 
1 65  GLU n 
1 66  LYS n 
1 67  LYS n 
1 68  GLY n 
1 69  GLY n 
1 70  LEU n 
1 71  ARG n 
1 72  GLU n 
1 73  LEU n 
1 74  TYR n 
1 75  ASP n 
1 76  ARG n 
1 77  GLY n 
1 78  PRO n 
1 79  PRO n 
1 80  HIS n 
1 81  ALA n 
1 82  PHE n 
1 83  PHE n 
1 84  LEU n 
1 85  VAL n 
1 86  LYS n 
1 87  PHE n 
1 88  TRP n 
1 89  ALA n 
1 90  ASP n 
1 91  LEU n 
1 92  ASN n 
1 93  TRP n 
1 94  GLY n 
1 95  PRO n 
1 96  SER n 
1 97  GLY n 
1 98  GLU n 
1 99  GLU n 
1 100 ALA n 
1 101 GLY n 
1 102 ALA n 
1 103 GLY n 
1 104 GLY n 
1 105 SER n 
1 106 ILE n 
1 107 SER n 
1 108 SER n 
1 109 GLY n 
1 110 GLY n 
1 111 PHE n 
1 112 TYR n 
1 113 GLY n 
1 114 VAL n 
1 115 SER n 
1 116 SER n 
1 117 GLN n 
1 118 TYR n 
1 119 GLU n 
1 120 SER n 
1 121 LEU n 
1 122 GLU n 
1 123 HIS n 
1 124 MET n 
1 125 THR n 
1 126 LEU n 
1 127 THR n 
1 128 CYS n 
1 129 SER n 
1 130 SER n 
1 131 LYS n 
1 132 VAL n 
1 133 CYS n 
1 134 SER n 
1 135 PHE n 
1 136 GLY n 
1 137 LYS n 
1 138 GLN n 
1 139 VAL n 
1 140 VAL n 
1 141 GLU n 
1 142 LYS n 
1 143 VAL n 
1 144 GLU n 
1 145 THR n 
1 146 GLU n 
1 147 ARG n 
1 148 ALA n 
1 149 GLN n 
1 150 LEU n 
1 151 GLU n 
1 152 ASP n 
1 153 GLY n 
1 154 ARG n 
1 155 PHE n 
1 156 VAL n 
1 157 TYR n 
1 158 ARG n 
1 159 LEU n 
1 160 LEU n 
1 161 ARG n 
1 162 SER n 
1 163 PRO n 
1 164 MET n 
1 165 CYS n 
1 166 GLU n 
1 167 TYR n 
1 168 LEU n 
1 169 VAL n 
1 170 ASN n 
1 171 PHE n 
1 172 LEU n 
1 173 HIS n 
1 174 LYS n 
1 175 LEU n 
1 176 ARG n 
1 177 GLN n 
1 178 LEU n 
1 179 PRO n 
1 180 GLU n 
1 181 ARG n 
1 182 TYR n 
1 183 MET n 
1 184 MET n 
1 185 ASN n 
1 186 SER n 
1 187 VAL n 
1 188 LEU n 
1 189 GLU n 
1 190 ASN n 
1 191 PHE n 
1 192 THR n 
1 193 ILE n 
1 194 LEU n 
1 195 GLN n 
1 196 VAL n 
1 197 VAL n 
1 198 THR n 
1 199 ASN n 
1 200 ARG n 
1 201 ASP n 
1 202 THR n 
1 203 GLN n 
1 204 GLU n 
1 205 LEU n 
1 206 LEU n 
1 207 LEU n 
1 208 CYS n 
1 209 THR n 
1 210 ALA n 
1 211 TYR n 
1 212 VAL n 
1 213 PHE n 
1 214 GLU n 
1 215 VAL n 
1 216 SER n 
1 217 THR n 
1 218 SER n 
1 219 GLU n 
1 220 ARG n 
1 221 GLY n 
1 222 ALA n 
1 223 GLN n 
1 224 HIS n 
1 225 HIS n 
1 226 ILE n 
1 227 TYR n 
1 228 ARG n 
1 229 LEU n 
1 230 VAL n 
1 231 ARG n 
1 232 ASP n 
1 233 VAL n 
1 234 GLU n 
1 235 HIS n 
1 236 HIS n 
1 237 HIS n 
1 238 HIS n 
1 239 HIS n 
1 240 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   240 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'TEAD2, TEF4' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1H3W non-polymer         . '~{N}-[2-(5-phenylmethoxy-1~{H}-indol-3-yl)ethyl]methanesulfonamide' ? 'C18 H20 N2 O3 S' 344.428 
ALA   'L-peptide linking' y ALANINE                                                              ? 'C3 H7 N O2'      89.093  
ARG   'L-peptide linking' y ARGININE                                                             ? 'C6 H15 N4 O2 1'  175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                           ? 'C4 H8 N2 O3'     132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                                      ? 'C4 H7 N O4'      133.103 
CYS   'L-peptide linking' y CYSTEINE                                                             ? 'C3 H7 N O2 S'    121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                            ? 'C5 H10 N2 O3'    146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                                      ? 'C5 H9 N O4'      147.129 
GLY   'peptide linking'   y GLYCINE                                                              ? 'C2 H5 N O2'      75.067  
HIS   'L-peptide linking' y HISTIDINE                                                            ? 'C6 H10 N3 O2 1'  156.162 
HOH   non-polymer         . WATER                                                                ? 'H2 O'            18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                                           ? 'C6 H13 N O2'     131.173 
LEU   'L-peptide linking' y LEUCINE                                                              ? 'C6 H13 N O2'     131.173 
LYS   'L-peptide linking' y LYSINE                                                               ? 'C6 H15 N2 O2 1'  147.195 
MET   'L-peptide linking' y METHIONINE                                                           ? 'C5 H11 N O2 S'   149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                                        ? 'C9 H11 N O2'     165.189 
PRO   'L-peptide linking' y PROLINE                                                              ? 'C5 H9 N O2'      115.130 
SER   'L-peptide linking' y SERINE                                                               ? 'C3 H7 N O3'      105.093 
THR   'L-peptide linking' y THREONINE                                                            ? 'C4 H9 N O3'      119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                           ? 'C11 H12 N2 O2'   204.225 
TYR   'L-peptide linking' y TYROSINE                                                             ? 'C9 H11 N O3'     181.189 
VAL   'L-peptide linking' y VALINE                                                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   216 ?   ?   ?   A . n 
A 1 2   ALA 2   217 ?   ?   ?   A . n 
A 1 3   TRP 3   218 ?   ?   ?   A . n 
A 1 4   GLN 4   219 ?   ?   ?   A . n 
A 1 5   ALA 5   220 ?   ?   ?   A . n 
A 1 6   ARG 6   221 ?   ?   ?   A . n 
A 1 7   GLY 7   222 222 GLY GLY A . n 
A 1 8   LEU 8   223 223 LEU LEU A . n 
A 1 9   GLY 9   224 224 GLY GLY A . n 
A 1 10  THR 10  225 225 THR THR A . n 
A 1 11  ALA 11  226 226 ALA ALA A . n 
A 1 12  ARG 12  227 227 ARG ARG A . n 
A 1 13  LEU 13  228 228 LEU LEU A . n 
A 1 14  GLN 14  229 229 GLN GLN A . n 
A 1 15  LEU 15  230 230 LEU LEU A . n 
A 1 16  VAL 16  231 231 VAL VAL A . n 
A 1 17  GLU 17  232 232 GLU GLU A . n 
A 1 18  PHE 18  233 233 PHE PHE A . n 
A 1 19  SER 19  234 234 SER SER A . n 
A 1 20  ALA 20  235 235 ALA ALA A . n 
A 1 21  PHE 21  236 236 PHE PHE A . n 
A 1 22  VAL 22  237 237 VAL VAL A . n 
A 1 23  GLU 23  238 238 GLU GLU A . n 
A 1 24  PRO 24  239 239 PRO PRO A . n 
A 1 25  PRO 25  240 240 PRO PRO A . n 
A 1 26  ASP 26  241 ?   ?   ?   A . n 
A 1 27  ALA 27  242 ?   ?   ?   A . n 
A 1 28  VAL 28  243 ?   ?   ?   A . n 
A 1 29  ASP 29  244 ?   ?   ?   A . n 
A 1 30  SER 30  245 ?   ?   ?   A . n 
A 1 31  TYR 31  246 ?   ?   ?   A . n 
A 1 32  GLN 32  247 ?   ?   ?   A . n 
A 1 33  ARG 33  248 248 ARG ARG A . n 
A 1 34  HIS 34  249 249 HIS HIS A . n 
A 1 35  LEU 35  250 250 LEU LEU A . n 
A 1 36  PHE 36  251 251 PHE PHE A . n 
A 1 37  VAL 37  252 252 VAL VAL A . n 
A 1 38  HIS 38  253 253 HIS HIS A . n 
A 1 39  ILE 39  254 254 ILE ILE A . n 
A 1 40  SER 40  255 255 SER SER A . n 
A 1 41  GLN 41  256 256 GLN GLN A . n 
A 1 42  HIS 42  257 ?   ?   ?   A . n 
A 1 43  CYS 43  258 ?   ?   ?   A . n 
A 1 44  PRO 44  259 ?   ?   ?   A . n 
A 1 45  SER 45  260 ?   ?   ?   A . n 
A 1 46  PRO 46  261 ?   ?   ?   A . n 
A 1 47  GLY 47  262 ?   ?   ?   A . n 
A 1 48  ALA 48  263 ?   ?   ?   A . n 
A 1 49  PRO 49  264 264 PRO PRO A . n 
A 1 50  PRO 50  265 265 PRO PRO A . n 
A 1 51  LEU 51  266 266 LEU LEU A . n 
A 1 52  GLU 52  267 267 GLU GLU A . n 
A 1 53  SER 53  268 268 SER SER A . n 
A 1 54  VAL 54  269 269 VAL VAL A . n 
A 1 55  ASP 55  270 270 ASP ASP A . n 
A 1 56  VAL 56  271 271 VAL VAL A . n 
A 1 57  ARG 57  272 272 ARG ARG A . n 
A 1 58  GLN 58  273 273 GLN GLN A . n 
A 1 59  ILE 59  274 274 ILE ILE A . n 
A 1 60  TYR 60  275 275 TYR TYR A . n 
A 1 61  ASP 61  276 276 ASP ASP A . n 
A 1 62  LYS 62  277 277 LYS LYS A . n 
A 1 63  PHE 63  278 278 PHE PHE A . n 
A 1 64  PRO 64  279 279 PRO PRO A . n 
A 1 65  GLU 65  280 280 GLU GLU A . n 
A 1 66  LYS 66  281 281 LYS LYS A . n 
A 1 67  LYS 67  282 282 LYS LYS A . n 
A 1 68  GLY 68  283 283 GLY GLY A . n 
A 1 69  GLY 69  284 284 GLY GLY A . n 
A 1 70  LEU 70  285 285 LEU LEU A . n 
A 1 71  ARG 71  286 286 ARG ARG A . n 
A 1 72  GLU 72  287 287 GLU GLU A . n 
A 1 73  LEU 73  288 288 LEU LEU A . n 
A 1 74  TYR 74  289 289 TYR TYR A . n 
A 1 75  ASP 75  290 290 ASP ASP A . n 
A 1 76  ARG 76  291 291 ARG ARG A . n 
A 1 77  GLY 77  292 292 GLY GLY A . n 
A 1 78  PRO 78  293 293 PRO PRO A . n 
A 1 79  PRO 79  294 294 PRO PRO A . n 
A 1 80  HIS 80  295 295 HIS HIS A . n 
A 1 81  ALA 81  296 296 ALA ALA A . n 
A 1 82  PHE 82  297 297 PHE PHE A . n 
A 1 83  PHE 83  298 298 PHE PHE A . n 
A 1 84  LEU 84  299 299 LEU LEU A . n 
A 1 85  VAL 85  300 300 VAL VAL A . n 
A 1 86  LYS 86  301 301 LYS LYS A . n 
A 1 87  PHE 87  302 302 PHE PHE A . n 
A 1 88  TRP 88  303 303 TRP TRP A . n 
A 1 89  ALA 89  304 304 ALA ALA A . n 
A 1 90  ASP 90  305 305 ASP ASP A . n 
A 1 91  LEU 91  306 306 LEU LEU A . n 
A 1 92  ASN 92  307 307 ASN ASN A . n 
A 1 93  TRP 93  308 308 TRP TRP A . n 
A 1 94  GLY 94  309 ?   ?   ?   A . n 
A 1 95  PRO 95  310 ?   ?   ?   A . n 
A 1 96  SER 96  311 ?   ?   ?   A . n 
A 1 97  GLY 97  312 ?   ?   ?   A . n 
A 1 98  GLU 98  313 ?   ?   ?   A . n 
A 1 99  GLU 99  314 ?   ?   ?   A . n 
A 1 100 ALA 100 315 ?   ?   ?   A . n 
A 1 101 GLY 101 316 ?   ?   ?   A . n 
A 1 102 ALA 102 317 ?   ?   ?   A . n 
A 1 103 GLY 103 318 ?   ?   ?   A . n 
A 1 104 GLY 104 319 ?   ?   ?   A . n 
A 1 105 SER 105 320 ?   ?   ?   A . n 
A 1 106 ILE 106 321 ?   ?   ?   A . n 
A 1 107 SER 107 322 322 SER SER A . n 
A 1 108 SER 108 323 323 SER SER A . n 
A 1 109 GLY 109 324 324 GLY GLY A . n 
A 1 110 GLY 110 325 325 GLY GLY A . n 
A 1 111 PHE 111 326 326 PHE PHE A . n 
A 1 112 TYR 112 327 327 TYR TYR A . n 
A 1 113 GLY 113 328 328 GLY GLY A . n 
A 1 114 VAL 114 329 329 VAL VAL A . n 
A 1 115 SER 115 330 330 SER SER A . n 
A 1 116 SER 116 331 331 SER SER A . n 
A 1 117 GLN 117 332 332 GLN GLN A . n 
A 1 118 TYR 118 333 333 TYR TYR A . n 
A 1 119 GLU 119 334 334 GLU GLU A . n 
A 1 120 SER 120 335 335 SER SER A . n 
A 1 121 LEU 121 336 336 LEU LEU A . n 
A 1 122 GLU 122 337 337 GLU GLU A . n 
A 1 123 HIS 123 338 338 HIS HIS A . n 
A 1 124 MET 124 339 339 MET MET A . n 
A 1 125 THR 125 340 340 THR THR A . n 
A 1 126 LEU 126 341 341 LEU LEU A . n 
A 1 127 THR 127 342 342 THR THR A . n 
A 1 128 CYS 128 343 343 CYS CYS A . n 
A 1 129 SER 129 344 344 SER SER A . n 
A 1 130 SER 130 345 345 SER SER A . n 
A 1 131 LYS 131 346 346 LYS LYS A . n 
A 1 132 VAL 132 347 347 VAL VAL A . n 
A 1 133 CYS 133 348 348 CYS CYS A . n 
A 1 134 SER 134 349 349 SER SER A . n 
A 1 135 PHE 135 350 350 PHE PHE A . n 
A 1 136 GLY 136 351 351 GLY GLY A . n 
A 1 137 LYS 137 352 352 LYS LYS A . n 
A 1 138 GLN 138 353 353 GLN GLN A . n 
A 1 139 VAL 139 354 354 VAL VAL A . n 
A 1 140 VAL 140 355 355 VAL VAL A . n 
A 1 141 GLU 141 356 356 GLU GLU A . n 
A 1 142 LYS 142 357 357 LYS LYS A . n 
A 1 143 VAL 143 358 358 VAL VAL A . n 
A 1 144 GLU 144 359 359 GLU GLU A . n 
A 1 145 THR 145 360 360 THR THR A . n 
A 1 146 GLU 146 361 361 GLU GLU A . n 
A 1 147 ARG 147 362 362 ARG ARG A . n 
A 1 148 ALA 148 363 363 ALA ALA A . n 
A 1 149 GLN 149 364 364 GLN GLN A . n 
A 1 150 LEU 150 365 365 LEU LEU A . n 
A 1 151 GLU 151 366 366 GLU GLU A . n 
A 1 152 ASP 152 367 367 ASP ASP A . n 
A 1 153 GLY 153 368 368 GLY GLY A . n 
A 1 154 ARG 154 369 369 ARG ARG A . n 
A 1 155 PHE 155 370 370 PHE PHE A . n 
A 1 156 VAL 156 371 371 VAL VAL A . n 
A 1 157 TYR 157 372 372 TYR TYR A . n 
A 1 158 ARG 158 373 373 ARG ARG A . n 
A 1 159 LEU 159 374 374 LEU LEU A . n 
A 1 160 LEU 160 375 375 LEU LEU A . n 
A 1 161 ARG 161 376 376 ARG ARG A . n 
A 1 162 SER 162 377 377 SER SER A . n 
A 1 163 PRO 163 378 378 PRO PRO A . n 
A 1 164 MET 164 379 379 MET MET A . n 
A 1 165 CYS 165 380 380 CYS CYS A . n 
A 1 166 GLU 166 381 381 GLU GLU A . n 
A 1 167 TYR 167 382 382 TYR TYR A . n 
A 1 168 LEU 168 383 383 LEU LEU A . n 
A 1 169 VAL 169 384 384 VAL VAL A . n 
A 1 170 ASN 170 385 385 ASN ASN A . n 
A 1 171 PHE 171 386 386 PHE PHE A . n 
A 1 172 LEU 172 387 387 LEU LEU A . n 
A 1 173 HIS 173 388 388 HIS HIS A . n 
A 1 174 LYS 174 389 389 LYS LYS A . n 
A 1 175 LEU 175 390 390 LEU LEU A . n 
A 1 176 ARG 176 391 391 ARG ARG A . n 
A 1 177 GLN 177 392 392 GLN GLN A . n 
A 1 178 LEU 178 393 393 LEU LEU A . n 
A 1 179 PRO 179 394 394 PRO PRO A . n 
A 1 180 GLU 180 395 395 GLU GLU A . n 
A 1 181 ARG 181 396 396 ARG ARG A . n 
A 1 182 TYR 182 397 397 TYR TYR A . n 
A 1 183 MET 183 398 398 MET MET A . n 
A 1 184 MET 184 399 399 MET MET A . n 
A 1 185 ASN 185 400 400 ASN ASN A . n 
A 1 186 SER 186 401 401 SER SER A . n 
A 1 187 VAL 187 402 402 VAL VAL A . n 
A 1 188 LEU 188 403 403 LEU LEU A . n 
A 1 189 GLU 189 404 404 GLU GLU A . n 
A 1 190 ASN 190 405 405 ASN ASN A . n 
A 1 191 PHE 191 406 406 PHE PHE A . n 
A 1 192 THR 192 407 407 THR THR A . n 
A 1 193 ILE 193 408 408 ILE ILE A . n 
A 1 194 LEU 194 409 409 LEU LEU A . n 
A 1 195 GLN 195 410 410 GLN GLN A . n 
A 1 196 VAL 196 411 411 VAL VAL A . n 
A 1 197 VAL 197 412 412 VAL VAL A . n 
A 1 198 THR 198 413 413 THR THR A . n 
A 1 199 ASN 199 414 414 ASN ASN A . n 
A 1 200 ARG 200 415 415 ARG ARG A . n 
A 1 201 ASP 201 416 416 ASP ASP A . n 
A 1 202 THR 202 417 417 THR THR A . n 
A 1 203 GLN 203 418 418 GLN GLN A . n 
A 1 204 GLU 204 419 419 GLU GLU A . n 
A 1 205 LEU 205 420 420 LEU LEU A . n 
A 1 206 LEU 206 421 421 LEU LEU A . n 
A 1 207 LEU 207 422 422 LEU LEU A . n 
A 1 208 CYS 208 423 423 CYS CYS A . n 
A 1 209 THR 209 424 424 THR THR A . n 
A 1 210 ALA 210 425 425 ALA ALA A . n 
A 1 211 TYR 211 426 426 TYR TYR A . n 
A 1 212 VAL 212 427 427 VAL VAL A . n 
A 1 213 PHE 213 428 428 PHE PHE A . n 
A 1 214 GLU 214 429 429 GLU GLU A . n 
A 1 215 VAL 215 430 430 VAL VAL A . n 
A 1 216 SER 216 431 431 SER SER A . n 
A 1 217 THR 217 432 432 THR THR A . n 
A 1 218 SER 218 433 433 SER SER A . n 
A 1 219 GLU 219 434 434 GLU GLU A . n 
A 1 220 ARG 220 435 435 ARG ARG A . n 
A 1 221 GLY 221 436 436 GLY GLY A . n 
A 1 222 ALA 222 437 437 ALA ALA A . n 
A 1 223 GLN 223 438 438 GLN GLN A . n 
A 1 224 HIS 224 439 439 HIS HIS A . n 
A 1 225 HIS 225 440 440 HIS HIS A . n 
A 1 226 ILE 226 441 441 ILE ILE A . n 
A 1 227 TYR 227 442 442 TYR TYR A . n 
A 1 228 ARG 228 443 443 ARG ARG A . n 
A 1 229 LEU 229 444 444 LEU LEU A . n 
A 1 230 VAL 230 445 445 VAL VAL A . n 
A 1 231 ARG 231 446 446 ARG ARG A . n 
A 1 232 ASP 232 447 447 ASP ASP A . n 
A 1 233 VAL 233 448 ?   ?   ?   A . n 
A 1 234 GLU 234 449 ?   ?   ?   A . n 
A 1 235 HIS 235 450 ?   ?   ?   A . n 
A 1 236 HIS 236 451 ?   ?   ?   A . n 
A 1 237 HIS 237 452 ?   ?   ?   A . n 
A 1 238 HIS 238 453 ?   ?   ?   A . n 
A 1 239 HIS 239 454 ?   ?   ?   A . n 
A 1 240 HIS 240 455 ?   ?   ?   A . n 
B 1 1   MET 1   216 ?   ?   ?   B . n 
B 1 2   ALA 2   217 ?   ?   ?   B . n 
B 1 3   TRP 3   218 ?   ?   ?   B . n 
B 1 4   GLN 4   219 ?   ?   ?   B . n 
B 1 5   ALA 5   220 220 ALA ALA B . n 
B 1 6   ARG 6   221 221 ARG ARG B . n 
B 1 7   GLY 7   222 222 GLY GLY B . n 
B 1 8   LEU 8   223 223 LEU LEU B . n 
B 1 9   GLY 9   224 224 GLY GLY B . n 
B 1 10  THR 10  225 225 THR THR B . n 
B 1 11  ALA 11  226 226 ALA ALA B . n 
B 1 12  ARG 12  227 227 ARG ARG B . n 
B 1 13  LEU 13  228 228 LEU LEU B . n 
B 1 14  GLN 14  229 229 GLN GLN B . n 
B 1 15  LEU 15  230 230 LEU LEU B . n 
B 1 16  VAL 16  231 231 VAL VAL B . n 
B 1 17  GLU 17  232 232 GLU GLU B . n 
B 1 18  PHE 18  233 233 PHE PHE B . n 
B 1 19  SER 19  234 234 SER SER B . n 
B 1 20  ALA 20  235 235 ALA ALA B . n 
B 1 21  PHE 21  236 236 PHE PHE B . n 
B 1 22  VAL 22  237 237 VAL VAL B . n 
B 1 23  GLU 23  238 238 GLU GLU B . n 
B 1 24  PRO 24  239 239 PRO PRO B . n 
B 1 25  PRO 25  240 240 PRO PRO B . n 
B 1 26  ASP 26  241 241 ASP ASP B . n 
B 1 27  ALA 27  242 242 ALA ALA B . n 
B 1 28  VAL 28  243 243 VAL VAL B . n 
B 1 29  ASP 29  244 244 ASP ASP B . n 
B 1 30  SER 30  245 245 SER SER B . n 
B 1 31  TYR 31  246 246 TYR TYR B . n 
B 1 32  GLN 32  247 247 GLN GLN B . n 
B 1 33  ARG 33  248 248 ARG ARG B . n 
B 1 34  HIS 34  249 249 HIS HIS B . n 
B 1 35  LEU 35  250 250 LEU LEU B . n 
B 1 36  PHE 36  251 251 PHE PHE B . n 
B 1 37  VAL 37  252 252 VAL VAL B . n 
B 1 38  HIS 38  253 253 HIS HIS B . n 
B 1 39  ILE 39  254 254 ILE ILE B . n 
B 1 40  SER 40  255 255 SER SER B . n 
B 1 41  GLN 41  256 256 GLN GLN B . n 
B 1 42  HIS 42  257 257 HIS HIS B . n 
B 1 43  CYS 43  258 ?   ?   ?   B . n 
B 1 44  PRO 44  259 ?   ?   ?   B . n 
B 1 45  SER 45  260 ?   ?   ?   B . n 
B 1 46  PRO 46  261 ?   ?   ?   B . n 
B 1 47  GLY 47  262 ?   ?   ?   B . n 
B 1 48  ALA 48  263 263 ALA ALA B . n 
B 1 49  PRO 49  264 264 PRO PRO B . n 
B 1 50  PRO 50  265 265 PRO PRO B . n 
B 1 51  LEU 51  266 266 LEU LEU B . n 
B 1 52  GLU 52  267 267 GLU GLU B . n 
B 1 53  SER 53  268 268 SER SER B . n 
B 1 54  VAL 54  269 269 VAL VAL B . n 
B 1 55  ASP 55  270 270 ASP ASP B . n 
B 1 56  VAL 56  271 271 VAL VAL B . n 
B 1 57  ARG 57  272 272 ARG ARG B . n 
B 1 58  GLN 58  273 273 GLN GLN B . n 
B 1 59  ILE 59  274 274 ILE ILE B . n 
B 1 60  TYR 60  275 275 TYR TYR B . n 
B 1 61  ASP 61  276 276 ASP ASP B . n 
B 1 62  LYS 62  277 277 LYS LYS B . n 
B 1 63  PHE 63  278 278 PHE PHE B . n 
B 1 64  PRO 64  279 279 PRO PRO B . n 
B 1 65  GLU 65  280 280 GLU GLU B . n 
B 1 66  LYS 66  281 281 LYS LYS B . n 
B 1 67  LYS 67  282 282 LYS LYS B . n 
B 1 68  GLY 68  283 283 GLY GLY B . n 
B 1 69  GLY 69  284 284 GLY GLY B . n 
B 1 70  LEU 70  285 285 LEU LEU B . n 
B 1 71  ARG 71  286 286 ARG ARG B . n 
B 1 72  GLU 72  287 287 GLU GLU B . n 
B 1 73  LEU 73  288 288 LEU LEU B . n 
B 1 74  TYR 74  289 289 TYR TYR B . n 
B 1 75  ASP 75  290 290 ASP ASP B . n 
B 1 76  ARG 76  291 291 ARG ARG B . n 
B 1 77  GLY 77  292 292 GLY GLY B . n 
B 1 78  PRO 78  293 293 PRO PRO B . n 
B 1 79  PRO 79  294 294 PRO PRO B . n 
B 1 80  HIS 80  295 295 HIS HIS B . n 
B 1 81  ALA 81  296 296 ALA ALA B . n 
B 1 82  PHE 82  297 297 PHE PHE B . n 
B 1 83  PHE 83  298 298 PHE PHE B . n 
B 1 84  LEU 84  299 299 LEU LEU B . n 
B 1 85  VAL 85  300 300 VAL VAL B . n 
B 1 86  LYS 86  301 301 LYS LYS B . n 
B 1 87  PHE 87  302 302 PHE PHE B . n 
B 1 88  TRP 88  303 303 TRP TRP B . n 
B 1 89  ALA 89  304 304 ALA ALA B . n 
B 1 90  ASP 90  305 305 ASP ASP B . n 
B 1 91  LEU 91  306 306 LEU LEU B . n 
B 1 92  ASN 92  307 307 ASN ASN B . n 
B 1 93  TRP 93  308 308 TRP TRP B . n 
B 1 94  GLY 94  309 ?   ?   ?   B . n 
B 1 95  PRO 95  310 ?   ?   ?   B . n 
B 1 96  SER 96  311 ?   ?   ?   B . n 
B 1 97  GLY 97  312 ?   ?   ?   B . n 
B 1 98  GLU 98  313 ?   ?   ?   B . n 
B 1 99  GLU 99  314 ?   ?   ?   B . n 
B 1 100 ALA 100 315 ?   ?   ?   B . n 
B 1 101 GLY 101 316 ?   ?   ?   B . n 
B 1 102 ALA 102 317 ?   ?   ?   B . n 
B 1 103 GLY 103 318 ?   ?   ?   B . n 
B 1 104 GLY 104 319 ?   ?   ?   B . n 
B 1 105 SER 105 320 ?   ?   ?   B . n 
B 1 106 ILE 106 321 ?   ?   ?   B . n 
B 1 107 SER 107 322 ?   ?   ?   B . n 
B 1 108 SER 108 323 323 SER ALA B . n 
B 1 109 GLY 109 324 324 GLY GLY B . n 
B 1 110 GLY 110 325 325 GLY GLY B . n 
B 1 111 PHE 111 326 326 PHE PHE B . n 
B 1 112 TYR 112 327 327 TYR TYR B . n 
B 1 113 GLY 113 328 328 GLY GLY B . n 
B 1 114 VAL 114 329 329 VAL VAL B . n 
B 1 115 SER 115 330 330 SER SER B . n 
B 1 116 SER 116 331 331 SER SER B . n 
B 1 117 GLN 117 332 332 GLN GLN B . n 
B 1 118 TYR 118 333 333 TYR TYR B . n 
B 1 119 GLU 119 334 334 GLU GLU B . n 
B 1 120 SER 120 335 335 SER SER B . n 
B 1 121 LEU 121 336 336 LEU LEU B . n 
B 1 122 GLU 122 337 337 GLU GLU B . n 
B 1 123 HIS 123 338 338 HIS HIS B . n 
B 1 124 MET 124 339 339 MET MET B . n 
B 1 125 THR 125 340 340 THR THR B . n 
B 1 126 LEU 126 341 341 LEU LEU B . n 
B 1 127 THR 127 342 342 THR THR B . n 
B 1 128 CYS 128 343 343 CYS CYS B . n 
B 1 129 SER 129 344 344 SER SER B . n 
B 1 130 SER 130 345 345 SER SER B . n 
B 1 131 LYS 131 346 346 LYS LYS B . n 
B 1 132 VAL 132 347 347 VAL VAL B . n 
B 1 133 CYS 133 348 348 CYS CYS B . n 
B 1 134 SER 134 349 349 SER SER B . n 
B 1 135 PHE 135 350 350 PHE PHE B . n 
B 1 136 GLY 136 351 351 GLY GLY B . n 
B 1 137 LYS 137 352 352 LYS LYS B . n 
B 1 138 GLN 138 353 353 GLN GLN B . n 
B 1 139 VAL 139 354 354 VAL VAL B . n 
B 1 140 VAL 140 355 355 VAL VAL B . n 
B 1 141 GLU 141 356 356 GLU GLU B . n 
B 1 142 LYS 142 357 357 LYS LYS B . n 
B 1 143 VAL 143 358 358 VAL VAL B . n 
B 1 144 GLU 144 359 359 GLU GLU B . n 
B 1 145 THR 145 360 360 THR THR B . n 
B 1 146 GLU 146 361 361 GLU GLU B . n 
B 1 147 ARG 147 362 362 ARG ARG B . n 
B 1 148 ALA 148 363 363 ALA ALA B . n 
B 1 149 GLN 149 364 364 GLN GLN B . n 
B 1 150 LEU 150 365 365 LEU LEU B . n 
B 1 151 GLU 151 366 366 GLU GLU B . n 
B 1 152 ASP 152 367 367 ASP ASP B . n 
B 1 153 GLY 153 368 368 GLY GLY B . n 
B 1 154 ARG 154 369 369 ARG ARG B . n 
B 1 155 PHE 155 370 370 PHE PHE B . n 
B 1 156 VAL 156 371 371 VAL VAL B . n 
B 1 157 TYR 157 372 372 TYR TYR B . n 
B 1 158 ARG 158 373 373 ARG ARG B . n 
B 1 159 LEU 159 374 374 LEU LEU B . n 
B 1 160 LEU 160 375 375 LEU LEU B . n 
B 1 161 ARG 161 376 376 ARG ARG B . n 
B 1 162 SER 162 377 377 SER SER B . n 
B 1 163 PRO 163 378 378 PRO PRO B . n 
B 1 164 MET 164 379 379 MET MET B . n 
B 1 165 CYS 165 380 380 CYS CYS B . n 
B 1 166 GLU 166 381 381 GLU GLU B . n 
B 1 167 TYR 167 382 382 TYR TYR B . n 
B 1 168 LEU 168 383 383 LEU LEU B . n 
B 1 169 VAL 169 384 384 VAL VAL B . n 
B 1 170 ASN 170 385 385 ASN ASN B . n 
B 1 171 PHE 171 386 386 PHE PHE B . n 
B 1 172 LEU 172 387 387 LEU LEU B . n 
B 1 173 HIS 173 388 388 HIS HIS B . n 
B 1 174 LYS 174 389 389 LYS LYS B . n 
B 1 175 LEU 175 390 390 LEU LEU B . n 
B 1 176 ARG 176 391 391 ARG ARG B . n 
B 1 177 GLN 177 392 392 GLN GLN B . n 
B 1 178 LEU 178 393 393 LEU LEU B . n 
B 1 179 PRO 179 394 394 PRO PRO B . n 
B 1 180 GLU 180 395 395 GLU GLU B . n 
B 1 181 ARG 181 396 396 ARG ARG B . n 
B 1 182 TYR 182 397 397 TYR TYR B . n 
B 1 183 MET 183 398 398 MET MET B . n 
B 1 184 MET 184 399 399 MET MET B . n 
B 1 185 ASN 185 400 400 ASN ASN B . n 
B 1 186 SER 186 401 401 SER SER B . n 
B 1 187 VAL 187 402 402 VAL VAL B . n 
B 1 188 LEU 188 403 403 LEU LEU B . n 
B 1 189 GLU 189 404 404 GLU GLU B . n 
B 1 190 ASN 190 405 405 ASN ASN B . n 
B 1 191 PHE 191 406 406 PHE PHE B . n 
B 1 192 THR 192 407 407 THR THR B . n 
B 1 193 ILE 193 408 408 ILE ILE B . n 
B 1 194 LEU 194 409 409 LEU LEU B . n 
B 1 195 GLN 195 410 410 GLN GLN B . n 
B 1 196 VAL 196 411 411 VAL VAL B . n 
B 1 197 VAL 197 412 412 VAL VAL B . n 
B 1 198 THR 198 413 413 THR THR B . n 
B 1 199 ASN 199 414 414 ASN ASN B . n 
B 1 200 ARG 200 415 415 ARG ARG B . n 
B 1 201 ASP 201 416 416 ASP ASP B . n 
B 1 202 THR 202 417 417 THR THR B . n 
B 1 203 GLN 203 418 418 GLN GLN B . n 
B 1 204 GLU 204 419 419 GLU GLU B . n 
B 1 205 LEU 205 420 420 LEU LEU B . n 
B 1 206 LEU 206 421 421 LEU LEU B . n 
B 1 207 LEU 207 422 422 LEU LEU B . n 
B 1 208 CYS 208 423 423 CYS CYS B . n 
B 1 209 THR 209 424 424 THR THR B . n 
B 1 210 ALA 210 425 425 ALA ALA B . n 
B 1 211 TYR 211 426 426 TYR TYR B . n 
B 1 212 VAL 212 427 427 VAL VAL B . n 
B 1 213 PHE 213 428 428 PHE PHE B . n 
B 1 214 GLU 214 429 429 GLU GLU B . n 
B 1 215 VAL 215 430 430 VAL VAL B . n 
B 1 216 SER 216 431 431 SER SER B . n 
B 1 217 THR 217 432 432 THR THR B . n 
B 1 218 SER 218 433 433 SER SER B . n 
B 1 219 GLU 219 434 434 GLU GLU B . n 
B 1 220 ARG 220 435 435 ARG ARG B . n 
B 1 221 GLY 221 436 436 GLY GLY B . n 
B 1 222 ALA 222 437 437 ALA ALA B . n 
B 1 223 GLN 223 438 438 GLN GLN B . n 
B 1 224 HIS 224 439 439 HIS HIS B . n 
B 1 225 HIS 225 440 440 HIS HIS B . n 
B 1 226 ILE 226 441 441 ILE ILE B . n 
B 1 227 TYR 227 442 442 TYR TYR B . n 
B 1 228 ARG 228 443 443 ARG ARG B . n 
B 1 229 LEU 229 444 444 LEU LEU B . n 
B 1 230 VAL 230 445 445 VAL VAL B . n 
B 1 231 ARG 231 446 446 ARG ARG B . n 
B 1 232 ASP 232 447 447 ASP ASP B . n 
B 1 233 VAL 233 448 ?   ?   ?   B . n 
B 1 234 GLU 234 449 ?   ?   ?   B . n 
B 1 235 HIS 235 450 ?   ?   ?   B . n 
B 1 236 HIS 236 451 ?   ?   ?   B . n 
B 1 237 HIS 237 452 ?   ?   ?   B . n 
B 1 238 HIS 238 453 ?   ?   ?   B . n 
B 1 239 HIS 239 454 ?   ?   ?   B . n 
B 1 240 HIS 240 455 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1H3W 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1H3W 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 A1H3W 1 501 2 A1H3W LIG A . 
D 2 A1H3W 1 501 1 A1H3W LIG B . 
E 3 HOH   1 601 1 HOH   HOH B . 
E 3 HOH   2 602 3 HOH   HOH B . 
E 3 HOH   3 603 2 HOH   HOH B . 
E 3 HOH   4 604 4 HOH   HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 281 ? CG  ? A LYS 66  CG  
2  1 Y 1 A LYS 281 ? CD  ? A LYS 66  CD  
3  1 Y 1 A LYS 281 ? CE  ? A LYS 66  CE  
4  1 Y 1 A LYS 281 ? NZ  ? A LYS 66  NZ  
5  1 Y 1 A LYS 282 ? CG  ? A LYS 67  CG  
6  1 Y 1 A LYS 282 ? CD  ? A LYS 67  CD  
7  1 Y 1 A LYS 282 ? CE  ? A LYS 67  CE  
8  1 Y 1 A LYS 282 ? NZ  ? A LYS 67  NZ  
9  1 Y 1 A ARG 286 ? CG  ? A ARG 71  CG  
10 1 Y 1 A ARG 286 ? CD  ? A ARG 71  CD  
11 1 Y 1 A ARG 286 ? NE  ? A ARG 71  NE  
12 1 Y 1 A ARG 286 ? CZ  ? A ARG 71  CZ  
13 1 Y 1 A ARG 286 ? NH1 ? A ARG 71  NH1 
14 1 Y 1 A ARG 286 ? NH2 ? A ARG 71  NH2 
15 1 Y 1 B LYS 281 ? CG  ? B LYS 66  CG  
16 1 Y 1 B LYS 281 ? CD  ? B LYS 66  CD  
17 1 Y 1 B LYS 281 ? CE  ? B LYS 66  CE  
18 1 Y 1 B LYS 281 ? NZ  ? B LYS 66  NZ  
19 1 Y 1 B LYS 282 ? CD  ? B LYS 67  CD  
20 1 Y 1 B LYS 282 ? CE  ? B LYS 67  CE  
21 1 Y 1 B LYS 282 ? NZ  ? B LYS 67  NZ  
22 1 Y 1 B SER 323 ? OG  ? B SER 108 OG  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? ? '(1.20.1_4487: ???)' 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS       ? ? ? .                    2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? pointless ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER    ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   111.37 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8RXV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     114.292 
_cell.length_a_esd                 ? 
_cell.length_b                     61.391 
_cell.length_b_esd                 ? 
_cell.length_c                     80.041 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8RXV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8RXV 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.75 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          55.33 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2.8M sodium formate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            288 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-07-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9697 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE BM30A' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9697 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BM30A 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8RXV 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.05 
_reflns.d_resolution_low                               47.58 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     60218 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.14 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.08 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.05 
_reflns_shell.d_res_low                                     2.12 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3111 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.418 
_reflns_shell.pdbx_CC_star                                  0.768 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8RXV 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.05 
_refine.ls_d_res_low                             47.58 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     60218 
_refine.ls_number_reflns_R_free                  1811 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    94.72 
_refine.ls_percent_reflns_R_free                 3.01 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2494 
_refine.ls_R_factor_R_free                       0.2975 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2479 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.88 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 44.14 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.41 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.05 
_refine_hist.d_res_low                        47.58 
_refine_hist.number_atoms_solvent             4 
_refine_hist.number_atoms_total               3378 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3326 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         48 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  ? 3482 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.105  ? 4715 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 13.426 ? 471  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.056  ? 502  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.010  ? 604  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.05 2.11 . . 125 4068 86.00 . . . . 0.53   . . . . . . . . . . . 0.5315 
'X-RAY DIFFRACTION' 2.11 2.17 . . 140 4564 96.00 . . . . 0.5094 . . . . . . . . . . . 0.5328 
'X-RAY DIFFRACTION' 2.17 2.24 . . 142 4612 97.00 . . . . 0.4766 . . . . . . . . . . . 0.5220 
'X-RAY DIFFRACTION' 2.24 2.32 . . 148 4586 97.00 . . . . 0.43   . . . . . . . . . . . 0.4335 
'X-RAY DIFFRACTION' 2.32 2.41 . . 142 4571 96.00 . . . . 0.38   . . . . . . . . . . . 0.3886 
'X-RAY DIFFRACTION' 2.41 2.52 . . 140 4583 97.00 . . . . 0.36   . . . . . . . . . . . 0.3632 
'X-RAY DIFFRACTION' 2.52 2.65 . . 135 4444 94.00 . . . . 0.3378 . . . . . . . . . . . 0.4023 
'X-RAY DIFFRACTION' 2.65 2.82 . . 142 4580 96.00 . . . . 0.3242 . . . . . . . . . . . 0.3778 
'X-RAY DIFFRACTION' 2.82 3.04 . . 140 4585 97.00 . . . . 0.28   . . . . . . . . . . . 0.2867 
'X-RAY DIFFRACTION' 3.04 3.34 . . 142 4521 96.00 . . . . 0.2544 . . . . . . . . . . . 0.3740 
'X-RAY DIFFRACTION' 3.34 3.83 . . 141 4471 94.00 . . . . 0.2120 . . . . . . . . . . . 0.2649 
'X-RAY DIFFRACTION' 3.83 4.82 . . 137 4430 94.00 . . . . 0.1818 . . . . . . . . . . . 0.2702 
# 
_struct.entry_id                     8RXV 
_struct.title                        'TEAD2 with an inhibitor' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8RXV 
_struct_keywords.text            'inhibitor, complex, TRANSCRIPTION' 
_struct_keywords.pdbx_keywords   TRANSCRIPTION 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    TEAD2_HUMAN 
_struct_ref.pdbx_db_accession          Q15562 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;AWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHA
FFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLR
SPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD
;
_struct_ref.pdbx_align_begin           0 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8RXV A 2 ? 232 ? Q15562 217 ? 447 ? 217 447 
2 1 8RXV B 2 ? 232 ? Q15562 217 ? 447 ? 217 447 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8RXV MET A 1   ? UNP Q15562 ? ? 'initiating methionine' 216 1  
1 8RXV VAL A 233 ? UNP Q15562 ? ? 'expression tag'        448 2  
1 8RXV GLU A 234 ? UNP Q15562 ? ? 'expression tag'        449 3  
1 8RXV HIS A 235 ? UNP Q15562 ? ? 'expression tag'        450 4  
1 8RXV HIS A 236 ? UNP Q15562 ? ? 'expression tag'        451 5  
1 8RXV HIS A 237 ? UNP Q15562 ? ? 'expression tag'        452 6  
1 8RXV HIS A 238 ? UNP Q15562 ? ? 'expression tag'        453 7  
1 8RXV HIS A 239 ? UNP Q15562 ? ? 'expression tag'        454 8  
1 8RXV HIS A 240 ? UNP Q15562 ? ? 'expression tag'        455 9  
2 8RXV MET B 1   ? UNP Q15562 ? ? 'initiating methionine' 216 10 
2 8RXV VAL B 233 ? UNP Q15562 ? ? 'expression tag'        448 11 
2 8RXV GLU B 234 ? UNP Q15562 ? ? 'expression tag'        449 12 
2 8RXV HIS B 235 ? UNP Q15562 ? ? 'expression tag'        450 13 
2 8RXV HIS B 236 ? UNP Q15562 ? ? 'expression tag'        451 14 
2 8RXV HIS B 237 ? UNP Q15562 ? ? 'expression tag'        452 15 
2 8RXV HIS B 238 ? UNP Q15562 ? ? 'expression tag'        453 16 
2 8RXV HIS B 239 ? UNP Q15562 ? ? 'expression tag'        454 17 
2 8RXV HIS B 240 ? UNP Q15562 ? ? 'expression tag'        455 18 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C   
2 1 B,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ARG A 57  ? PHE A 63  ? ARG A 272 PHE A 278 5 ? 7  
HELX_P HELX_P2  AA2 GLY A 69  ? GLY A 77  ? GLY A 284 GLY A 292 1 ? 9  
HELX_P HELX_P3  AA3 PRO A 78  ? HIS A 80  ? PRO A 293 HIS A 295 5 ? 3  
HELX_P HELX_P4  AA4 CYS A 165 ? ARG A 176 ? CYS A 380 ARG A 391 1 ? 12 
HELX_P HELX_P5  AA5 GLU A 180 ? GLU A 189 ? GLU A 395 GLU A 404 1 ? 10 
HELX_P HELX_P6  AA6 PRO B 24  ? ASP B 29  ? PRO B 239 ASP B 244 5 ? 6  
HELX_P HELX_P7  AA7 ARG B 57  ? PHE B 63  ? ARG B 272 PHE B 278 5 ? 7  
HELX_P HELX_P8  AA8 GLY B 69  ? GLY B 77  ? GLY B 284 GLY B 292 1 ? 9  
HELX_P HELX_P9  AA9 PRO B 78  ? HIS B 80  ? PRO B 293 HIS B 295 5 ? 3  
HELX_P HELX_P10 AB1 CYS B 165 ? LEU B 178 ? CYS B 380 LEU B 393 1 ? 14 
HELX_P HELX_P11 AB2 GLU B 180 ? ASN B 190 ? GLU B 395 ASN B 405 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLU 23  A . ? GLU 238 A PRO 24  A ? PRO 239 A 1 4.36  
2 GLY 77  A . ? GLY 292 A PRO 78  A ? PRO 293 A 1 5.04  
3 GLY 109 A . ? GLY 324 A GLY 110 A ? GLY 325 A 1 5.24  
4 GLY 77  B . ? GLY 292 B PRO 78  B ? PRO 293 B 1 -2.63 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5  ? 
AA2 ? 14 ? 
AA3 ? 5  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA2 1  2  ? parallel      
AA2 2  3  ? anti-parallel 
AA2 3  4  ? parallel      
AA2 4  5  ? anti-parallel 
AA2 5  6  ? anti-parallel 
AA2 6  7  ? anti-parallel 
AA2 7  8  ? parallel      
AA2 8  9  ? anti-parallel 
AA2 9  10 ? anti-parallel 
AA2 10 11 ? anti-parallel 
AA2 11 12 ? parallel      
AA2 12 13 ? anti-parallel 
AA2 13 14 ? parallel      
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  HIS A 34  ? SER A 40  ? HIS A 249 SER A 255 
AA1 2  GLN A 14  ? VAL A 22  ? GLN A 229 VAL A 237 
AA1 3  TYR A 112 ? SER A 120 ? TYR A 327 SER A 335 
AA1 4  PHE A 155 ? PRO A 163 ? PHE A 370 PRO A 378 
AA1 5  GLN A 149 ? LEU A 150 ? GLN A 364 LEU A 365 
AA2 1  SER A 53  ? ASP A 55  ? SER A 268 ASP A 270 
AA2 2  GLN A 223 ? VAL A 230 ? GLN A 438 VAL A 445 
AA2 3  PHE A 82  ? ALA A 89  ? PHE A 297 ALA A 304 
AA2 4  LEU A 205 ? VAL A 215 ? LEU A 420 VAL A 430 
AA2 5  PHE A 191 ? ASN A 199 ? PHE A 406 ASN A 414 
AA2 6  THR A 125 ? SER A 134 ? THR A 340 SER A 349 
AA2 7  LYS A 137 ? ARG A 147 ? LYS A 352 ARG A 362 
AA2 8  LYS B 137 ? ARG B 147 ? LYS B 352 ARG B 362 
AA2 9  THR B 125 ? SER B 134 ? THR B 340 SER B 349 
AA2 10 PHE B 191 ? ASN B 199 ? PHE B 406 ASN B 414 
AA2 11 LEU B 205 ? VAL B 215 ? LEU B 420 VAL B 430 
AA2 12 PHE B 82  ? ALA B 89  ? PHE B 297 ALA B 304 
AA2 13 GLN B 223 ? VAL B 230 ? GLN B 438 VAL B 445 
AA2 14 GLU B 52  ? ASP B 55  ? GLU B 267 ASP B 270 
AA3 1  HIS B 34  ? SER B 40  ? HIS B 249 SER B 255 
AA3 2  GLN B 14  ? GLU B 23  ? GLN B 229 GLU B 238 
AA3 3  PHE B 111 ? SER B 120 ? PHE B 326 SER B 335 
AA3 4  PHE B 155 ? PRO B 163 ? PHE B 370 PRO B 378 
AA3 5  GLN B 149 ? LEU B 150 ? GLN B 364 LEU B 365 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  O ILE A 39  ? O ILE A 254 N PHE A 18  ? N PHE A 233 
AA1 2  3  N VAL A 16  ? N VAL A 231 O GLN A 117 ? O GLN A 332 
AA1 3  4  N TYR A 118 ? N TYR A 333 O TYR A 157 ? O TYR A 372 
AA1 4  5  O VAL A 156 ? O VAL A 371 N GLN A 149 ? N GLN A 364 
AA2 1  2  N VAL A 54  ? N VAL A 269 O ARG A 228 ? O ARG A 443 
AA2 2  3  O TYR A 227 ? O TYR A 442 N LEU A 84  ? N LEU A 299 
AA2 3  4  N PHE A 83  ? N PHE A 298 O ALA A 210 ? O ALA A 425 
AA2 4  5  O TYR A 211 ? O TYR A 426 N ILE A 193 ? N ILE A 408 
AA2 5  6  O THR A 192 ? O THR A 407 N CYS A 133 ? N CYS A 348 
AA2 6  7  N LEU A 126 ? N LEU A 341 O GLU A 146 ? O GLU A 361 
AA2 7  8  N GLU A 141 ? N GLU A 356 O VAL B 143 ? O VAL B 358 
AA2 8  9  O GLU B 144 ? O GLU B 359 N CYS B 128 ? N CYS B 343 
AA2 9  10 N CYS B 133 ? N CYS B 348 O THR B 192 ? O THR B 407 
AA2 10 11 N VAL B 197 ? N VAL B 412 O LEU B 207 ? O LEU B 422 
AA2 11 12 O ALA B 210 ? O ALA B 425 N PHE B 83  ? N PHE B 298 
AA2 12 13 N LEU B 84  ? N LEU B 299 O TYR B 227 ? O TYR B 442 
AA2 13 14 O ARG B 228 ? O ARG B 443 N GLU B 52  ? N GLU B 267 
AA3 1  2  O ILE B 39  ? O ILE B 254 N PHE B 18  ? N PHE B 233 
AA3 2  3  N VAL B 16  ? N VAL B 231 O GLN B 117 ? O GLN B 332 
AA3 3  4  N TYR B 118 ? N TYR B 333 O TYR B 157 ? O TYR B 372 
AA3 4  5  O VAL B 156 ? O VAL B 371 N GLN B 149 ? N GLN B 364 
# 
_pdbx_entry_details.entry_id                   8RXV 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             C 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_1              264 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             N 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              265 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CD 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              265 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                141.02 
_pdbx_validate_rmsd_angle.angle_target_value         128.40 
_pdbx_validate_rmsd_angle.angle_deviation            12.62 
_pdbx_validate_rmsd_angle.angle_standard_deviation   2.10 
_pdbx_validate_rmsd_angle.linker_flag                Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 238 ? ? -67.74  -94.08  
2  1 PRO A 239 ? ? -100.22 -144.10 
3  1 PRO A 265 ? ? -70.27  -93.04  
4  1 GLU A 280 ? ? -78.67  28.88   
5  1 ASP A 367 ? ? 75.90   40.22   
6  1 ARG A 446 ? ? -135.84 -46.52  
7  1 PRO B 279 ? ? -65.67  -154.11 
8  1 GLU B 280 ? ? -176.68 -168.96 
9  1 LYS B 281 ? ? 68.88   -15.20  
10 1 LYS B 282 ? ? 157.04  156.54  
11 1 ASP B 367 ? ? 74.49   78.00   
12 1 ARG B 369 ? ? 167.42  135.05  
13 1 LEU B 393 ? ? -39.45  135.89  
14 1 GLN B 418 ? ? 77.83   -8.25   
15 1 ARG B 446 ? ? -150.15 69.44   
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined 36.3121 52.3068 -8.0440  0.5706 ? 0.0413  ? 0.0337  ? 0.6234 ? 0.0053  ? 0.5171 ? 9.2262 ? -0.2599 
? -4.1050 ? 4.7293 ? 0.1348  ? 6.5196 ? 0.4444  ? -1.2512 ? 0.3428  ? 0.0608  ? -0.0334 ? 0.4125  ? -0.6797 ? 0.5123  ? -0.2962 ? 
2 'X-RAY DIFFRACTION' ? refined 49.9331 53.8666 -13.1876 0.8383 ? 0.0140  ? 0.0185  ? 1.0340 ? -0.1026 ? 0.5775 ? 0.4758 ? -0.7062 
? 0.6912  ? 3.1814 ? -1.7330 ? 1.1861 ? 0.0042  ? -1.5146 ? 1.3320  ? 1.0282  ? 0.4433  ? -0.3702 ? -0.3579 ? 1.4462  ? -0.0395 ? 
3 'X-RAY DIFFRACTION' ? refined 26.1360 54.0821 -22.4001 0.7988 ? 0.1261  ? -0.0654 ? 0.9458 ? 0.1327  ? 0.8404 ? 2.8013 ? 0.8946  
? -2.8339 ? 4.2859 ? 2.8426  ? 6.2615 ? -0.1587 ? 1.8048  ? 0.8448  ? -0.4016 ? 0.3021  ? 1.4377  ? -0.7286 ? -0.9721 ? -0.1675 ? 
4 'X-RAY DIFFRACTION' ? refined 24.1192 41.2053 -20.1814 0.8560 ? -0.1182 ? -0.1342 ? 0.9993 ? -0.0462 ? 0.9839 ? 3.0578 ? 1.2459  
? -1.8017 ? 6.2799 ? -0.9448 ? 7.1447 ? 0.1017  ? 1.2293  ? -1.4938 ? -1.4142 ? 0.3675  ? 0.7892  ? 2.3248  ? -0.9344 ? 0.3056  ? 
5 'X-RAY DIFFRACTION' ? refined 41.5507 52.4553 -18.8868 0.4420 ? 0.0350  ? -0.0284 ? 0.4652 ? 0.0102  ? 0.3900 ? 4.5307 ? 0.2717  
? -2.6934 ? 4.8848 ? -1.0201 ? 7.4879 ? -0.2342 ? -0.6868 ? 0.2122  ? -0.0421 ? 0.1450  ? -0.2759 ? 0.0969  ? 1.0429  ? -0.1677 ? 
6 'X-RAY DIFFRACTION' ? refined 38.3066 44.3136 -7.1311  0.7618 ? 0.1442  ? -0.0164 ? 0.6501 ? 0.0618  ? 0.5513 ? 2.8413 ? -0.2252 
? -3.7992 ? 0.6915 ? -1.2721 ? 8.6533 ? 0.1063  ? -0.6461 ? -0.0734 ? -0.0037 ? -0.0822 ? -0.1599 ? 0.4380  ? 0.8027  ? 0.1399  ? 
7 'X-RAY DIFFRACTION' ? refined 38.8745 50.1066 -21.7097 0.4958 ? 0.0748  ? -0.0918 ? 0.4387 ? -0.0063 ? 0.4939 ? 5.5525 ? 1.5333  
? -4.1514 ? 2.2992 ? -1.2338 ? 7.2513 ? 0.0710  ? -0.2158 ? 0.2138  ? -0.0244 ? 0.1206  ? 0.1348  ? 0.1102  ? 0.2858  ? -0.1536 ? 
8 'X-RAY DIFFRACTION' ? refined 45.7068 17.7097 -16.7553 0.4298 ? 0.0340  ? -0.0558 ? 0.3523 ? -0.0143 ? 0.4369 ? 8.8416 ? 1.0360  
? 0.8385  ? 2.7892 ? 1.2930  ? 7.7287 ? -0.1028 ? -0.2122 ? 0.1348  ? -0.1544 ? 0.2269  ? -0.3361 ? 0.1761  ? 0.5879  ? -0.1445 ? 
9 'X-RAY DIFFRACTION' ? refined 43.1090 21.8974 -17.0952 0.4068 ? 0.0497  ? -0.0233 ? 0.3896 ? 0.0190  ? 0.5057 ? 3.7480 ? -0.1614 
? 0.2225  ? 2.2365 ? 1.1814  ? 7.6142 ? -0.0292 ? -0.4034 ? 0.1516  ? -0.0749 ? 0.1645  ? -0.2380 ? -0.1897 ? -0.0170 ? -0.1255 ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 222 through 237 )
;
2 'X-RAY DIFFRACTION' 2 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 238 through 255 )
;
3 'X-RAY DIFFRACTION' 3 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 256 through 277 )
;
4 'X-RAY DIFFRACTION' 4 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 278 through 293 )
;
5 'X-RAY DIFFRACTION' 5 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 294 through 326 )
;
6 'X-RAY DIFFRACTION' 6 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 327 through 380 )
;
7 'X-RAY DIFFRACTION' 7 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'A' and (resid 381 through 447 )
;
8 'X-RAY DIFFRACTION' 8 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'B' and (resid 220 through 325 )
;
9 'X-RAY DIFFRACTION' 9 ? ? ? ? ? ? ? ? ? ? ? 
;chain 'B' and (resid 326 through 447 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 216 ? A MET 1   
2  1 Y 1 A ALA 217 ? A ALA 2   
3  1 Y 1 A TRP 218 ? A TRP 3   
4  1 Y 1 A GLN 219 ? A GLN 4   
5  1 Y 1 A ALA 220 ? A ALA 5   
6  1 Y 1 A ARG 221 ? A ARG 6   
7  1 Y 1 A ASP 241 ? A ASP 26  
8  1 Y 1 A ALA 242 ? A ALA 27  
9  1 Y 1 A VAL 243 ? A VAL 28  
10 1 Y 1 A ASP 244 ? A ASP 29  
11 1 Y 1 A SER 245 ? A SER 30  
12 1 Y 1 A TYR 246 ? A TYR 31  
13 1 Y 1 A GLN 247 ? A GLN 32  
14 1 Y 1 A HIS 257 ? A HIS 42  
15 1 Y 1 A CYS 258 ? A CYS 43  
16 1 Y 1 A PRO 259 ? A PRO 44  
17 1 Y 1 A SER 260 ? A SER 45  
18 1 Y 1 A PRO 261 ? A PRO 46  
19 1 Y 1 A GLY 262 ? A GLY 47  
20 1 Y 1 A ALA 263 ? A ALA 48  
21 1 Y 1 A GLY 309 ? A GLY 94  
22 1 Y 1 A PRO 310 ? A PRO 95  
23 1 Y 1 A SER 311 ? A SER 96  
24 1 Y 1 A GLY 312 ? A GLY 97  
25 1 Y 1 A GLU 313 ? A GLU 98  
26 1 Y 1 A GLU 314 ? A GLU 99  
27 1 Y 1 A ALA 315 ? A ALA 100 
28 1 Y 1 A GLY 316 ? A GLY 101 
29 1 Y 1 A ALA 317 ? A ALA 102 
30 1 Y 1 A GLY 318 ? A GLY 103 
31 1 Y 1 A GLY 319 ? A GLY 104 
32 1 Y 1 A SER 320 ? A SER 105 
33 1 Y 1 A ILE 321 ? A ILE 106 
34 1 Y 1 A VAL 448 ? A VAL 233 
35 1 Y 1 A GLU 449 ? A GLU 234 
36 1 Y 1 A HIS 450 ? A HIS 235 
37 1 Y 1 A HIS 451 ? A HIS 236 
38 1 Y 1 A HIS 452 ? A HIS 237 
39 1 Y 1 A HIS 453 ? A HIS 238 
40 1 Y 1 A HIS 454 ? A HIS 239 
41 1 Y 1 A HIS 455 ? A HIS 240 
42 1 Y 1 B MET 216 ? B MET 1   
43 1 Y 1 B ALA 217 ? B ALA 2   
44 1 Y 1 B TRP 218 ? B TRP 3   
45 1 Y 1 B GLN 219 ? B GLN 4   
46 1 Y 1 B CYS 258 ? B CYS 43  
47 1 Y 1 B PRO 259 ? B PRO 44  
48 1 Y 1 B SER 260 ? B SER 45  
49 1 Y 1 B PRO 261 ? B PRO 46  
50 1 Y 1 B GLY 262 ? B GLY 47  
51 1 Y 1 B GLY 309 ? B GLY 94  
52 1 Y 1 B PRO 310 ? B PRO 95  
53 1 Y 1 B SER 311 ? B SER 96  
54 1 Y 1 B GLY 312 ? B GLY 97  
55 1 Y 1 B GLU 313 ? B GLU 98  
56 1 Y 1 B GLU 314 ? B GLU 99  
57 1 Y 1 B ALA 315 ? B ALA 100 
58 1 Y 1 B GLY 316 ? B GLY 101 
59 1 Y 1 B ALA 317 ? B ALA 102 
60 1 Y 1 B GLY 318 ? B GLY 103 
61 1 Y 1 B GLY 319 ? B GLY 104 
62 1 Y 1 B SER 320 ? B SER 105 
63 1 Y 1 B ILE 321 ? B ILE 106 
64 1 Y 1 B SER 322 ? B SER 107 
65 1 Y 1 B VAL 448 ? B VAL 233 
66 1 Y 1 B GLU 449 ? B GLU 234 
67 1 Y 1 B HIS 450 ? B HIS 235 
68 1 Y 1 B HIS 451 ? B HIS 236 
69 1 Y 1 B HIS 452 ? B HIS 237 
70 1 Y 1 B HIS 453 ? B HIS 238 
71 1 Y 1 B HIS 454 ? B HIS 239 
72 1 Y 1 B HIS 455 ? B HIS 240 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1H3W C13  C Y N 1   
A1H3W C17  C Y N 2   
A1H3W C20  C Y N 3   
A1H3W C21  C Y N 4   
A1H3W C22  C Y N 5   
A1H3W C24  C Y N 6   
A1H3W C01  C N N 7   
A1H3W C06  C N N 8   
A1H3W C07  C N N 9   
A1H3W C08  C Y N 10  
A1H3W C09  C Y N 11  
A1H3W C11  C Y N 12  
A1H3W C12  C Y N 13  
A1H3W C14  C Y N 14  
A1H3W C16  C N N 15  
A1H3W C18  C Y N 16  
A1H3W C19  C Y N 17  
A1H3W C23  C Y N 18  
A1H3W N05  N N N 19  
A1H3W N10  N Y N 20  
A1H3W O03  O N N 21  
A1H3W O04  O N N 22  
A1H3W O15  O N N 23  
A1H3W S02  S N N 24  
A1H3W H1   H N N 25  
A1H3W H2   H N N 26  
A1H3W H3   H N N 27  
A1H3W H4   H N N 28  
A1H3W H5   H N N 29  
A1H3W H6   H N N 30  
A1H3W H7   H N N 31  
A1H3W H8   H N N 32  
A1H3W H9   H N N 33  
A1H3W H10  H N N 34  
A1H3W H11  H N N 35  
A1H3W H12  H N N 36  
A1H3W H13  H N N 37  
A1H3W H14  H N N 38  
A1H3W H15  H N N 39  
A1H3W H16  H N N 40  
A1H3W H17  H N N 41  
A1H3W H18  H N N 42  
A1H3W H19  H N N 43  
A1H3W H20  H N N 44  
ALA   N    N N N 45  
ALA   CA   C N S 46  
ALA   C    C N N 47  
ALA   O    O N N 48  
ALA   CB   C N N 49  
ALA   OXT  O N N 50  
ALA   H    H N N 51  
ALA   H2   H N N 52  
ALA   HA   H N N 53  
ALA   HB1  H N N 54  
ALA   HB2  H N N 55  
ALA   HB3  H N N 56  
ALA   HXT  H N N 57  
ARG   N    N N N 58  
ARG   CA   C N S 59  
ARG   C    C N N 60  
ARG   O    O N N 61  
ARG   CB   C N N 62  
ARG   CG   C N N 63  
ARG   CD   C N N 64  
ARG   NE   N N N 65  
ARG   CZ   C N N 66  
ARG   NH1  N N N 67  
ARG   NH2  N N N 68  
ARG   OXT  O N N 69  
ARG   H    H N N 70  
ARG   H2   H N N 71  
ARG   HA   H N N 72  
ARG   HB2  H N N 73  
ARG   HB3  H N N 74  
ARG   HG2  H N N 75  
ARG   HG3  H N N 76  
ARG   HD2  H N N 77  
ARG   HD3  H N N 78  
ARG   HE   H N N 79  
ARG   HH11 H N N 80  
ARG   HH12 H N N 81  
ARG   HH21 H N N 82  
ARG   HH22 H N N 83  
ARG   HXT  H N N 84  
ASN   N    N N N 85  
ASN   CA   C N S 86  
ASN   C    C N N 87  
ASN   O    O N N 88  
ASN   CB   C N N 89  
ASN   CG   C N N 90  
ASN   OD1  O N N 91  
ASN   ND2  N N N 92  
ASN   OXT  O N N 93  
ASN   H    H N N 94  
ASN   H2   H N N 95  
ASN   HA   H N N 96  
ASN   HB2  H N N 97  
ASN   HB3  H N N 98  
ASN   HD21 H N N 99  
ASN   HD22 H N N 100 
ASN   HXT  H N N 101 
ASP   N    N N N 102 
ASP   CA   C N S 103 
ASP   C    C N N 104 
ASP   O    O N N 105 
ASP   CB   C N N 106 
ASP   CG   C N N 107 
ASP   OD1  O N N 108 
ASP   OD2  O N N 109 
ASP   OXT  O N N 110 
ASP   H    H N N 111 
ASP   H2   H N N 112 
ASP   HA   H N N 113 
ASP   HB2  H N N 114 
ASP   HB3  H N N 115 
ASP   HD2  H N N 116 
ASP   HXT  H N N 117 
CYS   N    N N N 118 
CYS   CA   C N R 119 
CYS   C    C N N 120 
CYS   O    O N N 121 
CYS   CB   C N N 122 
CYS   SG   S N N 123 
CYS   OXT  O N N 124 
CYS   H    H N N 125 
CYS   H2   H N N 126 
CYS   HA   H N N 127 
CYS   HB2  H N N 128 
CYS   HB3  H N N 129 
CYS   HG   H N N 130 
CYS   HXT  H N N 131 
GLN   N    N N N 132 
GLN   CA   C N S 133 
GLN   C    C N N 134 
GLN   O    O N N 135 
GLN   CB   C N N 136 
GLN   CG   C N N 137 
GLN   CD   C N N 138 
GLN   OE1  O N N 139 
GLN   NE2  N N N 140 
GLN   OXT  O N N 141 
GLN   H    H N N 142 
GLN   H2   H N N 143 
GLN   HA   H N N 144 
GLN   HB2  H N N 145 
GLN   HB3  H N N 146 
GLN   HG2  H N N 147 
GLN   HG3  H N N 148 
GLN   HE21 H N N 149 
GLN   HE22 H N N 150 
GLN   HXT  H N N 151 
GLU   N    N N N 152 
GLU   CA   C N S 153 
GLU   C    C N N 154 
GLU   O    O N N 155 
GLU   CB   C N N 156 
GLU   CG   C N N 157 
GLU   CD   C N N 158 
GLU   OE1  O N N 159 
GLU   OE2  O N N 160 
GLU   OXT  O N N 161 
GLU   H    H N N 162 
GLU   H2   H N N 163 
GLU   HA   H N N 164 
GLU   HB2  H N N 165 
GLU   HB3  H N N 166 
GLU   HG2  H N N 167 
GLU   HG3  H N N 168 
GLU   HE2  H N N 169 
GLU   HXT  H N N 170 
GLY   N    N N N 171 
GLY   CA   C N N 172 
GLY   C    C N N 173 
GLY   O    O N N 174 
GLY   OXT  O N N 175 
GLY   H    H N N 176 
GLY   H2   H N N 177 
GLY   HA2  H N N 178 
GLY   HA3  H N N 179 
GLY   HXT  H N N 180 
HIS   N    N N N 181 
HIS   CA   C N S 182 
HIS   C    C N N 183 
HIS   O    O N N 184 
HIS   CB   C N N 185 
HIS   CG   C Y N 186 
HIS   ND1  N Y N 187 
HIS   CD2  C Y N 188 
HIS   CE1  C Y N 189 
HIS   NE2  N Y N 190 
HIS   OXT  O N N 191 
HIS   H    H N N 192 
HIS   H2   H N N 193 
HIS   HA   H N N 194 
HIS   HB2  H N N 195 
HIS   HB3  H N N 196 
HIS   HD1  H N N 197 
HIS   HD2  H N N 198 
HIS   HE1  H N N 199 
HIS   HE2  H N N 200 
HIS   HXT  H N N 201 
HOH   O    O N N 202 
HOH   H1   H N N 203 
HOH   H2   H N N 204 
ILE   N    N N N 205 
ILE   CA   C N S 206 
ILE   C    C N N 207 
ILE   O    O N N 208 
ILE   CB   C N S 209 
ILE   CG1  C N N 210 
ILE   CG2  C N N 211 
ILE   CD1  C N N 212 
ILE   OXT  O N N 213 
ILE   H    H N N 214 
ILE   H2   H N N 215 
ILE   HA   H N N 216 
ILE   HB   H N N 217 
ILE   HG12 H N N 218 
ILE   HG13 H N N 219 
ILE   HG21 H N N 220 
ILE   HG22 H N N 221 
ILE   HG23 H N N 222 
ILE   HD11 H N N 223 
ILE   HD12 H N N 224 
ILE   HD13 H N N 225 
ILE   HXT  H N N 226 
LEU   N    N N N 227 
LEU   CA   C N S 228 
LEU   C    C N N 229 
LEU   O    O N N 230 
LEU   CB   C N N 231 
LEU   CG   C N N 232 
LEU   CD1  C N N 233 
LEU   CD2  C N N 234 
LEU   OXT  O N N 235 
LEU   H    H N N 236 
LEU   H2   H N N 237 
LEU   HA   H N N 238 
LEU   HB2  H N N 239 
LEU   HB3  H N N 240 
LEU   HG   H N N 241 
LEU   HD11 H N N 242 
LEU   HD12 H N N 243 
LEU   HD13 H N N 244 
LEU   HD21 H N N 245 
LEU   HD22 H N N 246 
LEU   HD23 H N N 247 
LEU   HXT  H N N 248 
LYS   N    N N N 249 
LYS   CA   C N S 250 
LYS   C    C N N 251 
LYS   O    O N N 252 
LYS   CB   C N N 253 
LYS   CG   C N N 254 
LYS   CD   C N N 255 
LYS   CE   C N N 256 
LYS   NZ   N N N 257 
LYS   OXT  O N N 258 
LYS   H    H N N 259 
LYS   H2   H N N 260 
LYS   HA   H N N 261 
LYS   HB2  H N N 262 
LYS   HB3  H N N 263 
LYS   HG2  H N N 264 
LYS   HG3  H N N 265 
LYS   HD2  H N N 266 
LYS   HD3  H N N 267 
LYS   HE2  H N N 268 
LYS   HE3  H N N 269 
LYS   HZ1  H N N 270 
LYS   HZ2  H N N 271 
LYS   HZ3  H N N 272 
LYS   HXT  H N N 273 
MET   N    N N N 274 
MET   CA   C N S 275 
MET   C    C N N 276 
MET   O    O N N 277 
MET   CB   C N N 278 
MET   CG   C N N 279 
MET   SD   S N N 280 
MET   CE   C N N 281 
MET   OXT  O N N 282 
MET   H    H N N 283 
MET   H2   H N N 284 
MET   HA   H N N 285 
MET   HB2  H N N 286 
MET   HB3  H N N 287 
MET   HG2  H N N 288 
MET   HG3  H N N 289 
MET   HE1  H N N 290 
MET   HE2  H N N 291 
MET   HE3  H N N 292 
MET   HXT  H N N 293 
PHE   N    N N N 294 
PHE   CA   C N S 295 
PHE   C    C N N 296 
PHE   O    O N N 297 
PHE   CB   C N N 298 
PHE   CG   C Y N 299 
PHE   CD1  C Y N 300 
PHE   CD2  C Y N 301 
PHE   CE1  C Y N 302 
PHE   CE2  C Y N 303 
PHE   CZ   C Y N 304 
PHE   OXT  O N N 305 
PHE   H    H N N 306 
PHE   H2   H N N 307 
PHE   HA   H N N 308 
PHE   HB2  H N N 309 
PHE   HB3  H N N 310 
PHE   HD1  H N N 311 
PHE   HD2  H N N 312 
PHE   HE1  H N N 313 
PHE   HE2  H N N 314 
PHE   HZ   H N N 315 
PHE   HXT  H N N 316 
PRO   N    N N N 317 
PRO   CA   C N S 318 
PRO   C    C N N 319 
PRO   O    O N N 320 
PRO   CB   C N N 321 
PRO   CG   C N N 322 
PRO   CD   C N N 323 
PRO   OXT  O N N 324 
PRO   H    H N N 325 
PRO   HA   H N N 326 
PRO   HB2  H N N 327 
PRO   HB3  H N N 328 
PRO   HG2  H N N 329 
PRO   HG3  H N N 330 
PRO   HD2  H N N 331 
PRO   HD3  H N N 332 
PRO   HXT  H N N 333 
SER   N    N N N 334 
SER   CA   C N S 335 
SER   C    C N N 336 
SER   O    O N N 337 
SER   CB   C N N 338 
SER   OG   O N N 339 
SER   OXT  O N N 340 
SER   H    H N N 341 
SER   H2   H N N 342 
SER   HA   H N N 343 
SER   HB2  H N N 344 
SER   HB3  H N N 345 
SER   HG   H N N 346 
SER   HXT  H N N 347 
THR   N    N N N 348 
THR   CA   C N S 349 
THR   C    C N N 350 
THR   O    O N N 351 
THR   CB   C N R 352 
THR   OG1  O N N 353 
THR   CG2  C N N 354 
THR   OXT  O N N 355 
THR   H    H N N 356 
THR   H2   H N N 357 
THR   HA   H N N 358 
THR   HB   H N N 359 
THR   HG1  H N N 360 
THR   HG21 H N N 361 
THR   HG22 H N N 362 
THR   HG23 H N N 363 
THR   HXT  H N N 364 
TRP   N    N N N 365 
TRP   CA   C N S 366 
TRP   C    C N N 367 
TRP   O    O N N 368 
TRP   CB   C N N 369 
TRP   CG   C Y N 370 
TRP   CD1  C Y N 371 
TRP   CD2  C Y N 372 
TRP   NE1  N Y N 373 
TRP   CE2  C Y N 374 
TRP   CE3  C Y N 375 
TRP   CZ2  C Y N 376 
TRP   CZ3  C Y N 377 
TRP   CH2  C Y N 378 
TRP   OXT  O N N 379 
TRP   H    H N N 380 
TRP   H2   H N N 381 
TRP   HA   H N N 382 
TRP   HB2  H N N 383 
TRP   HB3  H N N 384 
TRP   HD1  H N N 385 
TRP   HE1  H N N 386 
TRP   HE3  H N N 387 
TRP   HZ2  H N N 388 
TRP   HZ3  H N N 389 
TRP   HH2  H N N 390 
TRP   HXT  H N N 391 
TYR   N    N N N 392 
TYR   CA   C N S 393 
TYR   C    C N N 394 
TYR   O    O N N 395 
TYR   CB   C N N 396 
TYR   CG   C Y N 397 
TYR   CD1  C Y N 398 
TYR   CD2  C Y N 399 
TYR   CE1  C Y N 400 
TYR   CE2  C Y N 401 
TYR   CZ   C Y N 402 
TYR   OH   O N N 403 
TYR   OXT  O N N 404 
TYR   H    H N N 405 
TYR   H2   H N N 406 
TYR   HA   H N N 407 
TYR   HB2  H N N 408 
TYR   HB3  H N N 409 
TYR   HD1  H N N 410 
TYR   HD2  H N N 411 
TYR   HE1  H N N 412 
TYR   HE2  H N N 413 
TYR   HH   H N N 414 
TYR   HXT  H N N 415 
VAL   N    N N N 416 
VAL   CA   C N S 417 
VAL   C    C N N 418 
VAL   O    O N N 419 
VAL   CB   C N N 420 
VAL   CG1  C N N 421 
VAL   CG2  C N N 422 
VAL   OXT  O N N 423 
VAL   H    H N N 424 
VAL   H2   H N N 425 
VAL   HA   H N N 426 
VAL   HB   H N N 427 
VAL   HG11 H N N 428 
VAL   HG12 H N N 429 
VAL   HG13 H N N 430 
VAL   HG21 H N N 431 
VAL   HG22 H N N 432 
VAL   HG23 H N N 433 
VAL   HXT  H N N 434 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1H3W C20 C21  doub Y N 1   
A1H3W C20 C19  sing Y N 2   
A1H3W C21 C22  sing Y N 3   
A1H3W C19 C18  doub Y N 4   
A1H3W C22 C17  doub Y N 5   
A1H3W C18 C17  sing Y N 6   
A1H3W C17 C16  sing N N 7   
A1H3W C16 O15  sing N N 8   
A1H3W O15 C14  sing N N 9   
A1H3W C23 C14  doub Y N 10  
A1H3W C23 C24  sing Y N 11  
A1H3W C14 C13  sing Y N 12  
A1H3W C24 C11  doub Y N 13  
A1H3W O04 S02  doub N N 14  
A1H3W C13 C12  doub Y N 15  
A1H3W C11 C12  sing Y N 16  
A1H3W C11 N10  sing Y N 17  
A1H3W C12 C08  sing Y N 18  
A1H3W O03 S02  doub N N 19  
A1H3W S02 N05  sing N N 20  
A1H3W S02 C01  sing N N 21  
A1H3W C06 N05  sing N N 22  
A1H3W C06 C07  sing N N 23  
A1H3W N10 C09  sing Y N 24  
A1H3W C08 C09  doub Y N 25  
A1H3W C08 C07  sing N N 26  
A1H3W C13 H1   sing N N 27  
A1H3W C20 H2   sing N N 28  
A1H3W C21 H3   sing N N 29  
A1H3W C22 H4   sing N N 30  
A1H3W C24 H5   sing N N 31  
A1H3W C01 H6   sing N N 32  
A1H3W C01 H7   sing N N 33  
A1H3W C01 H8   sing N N 34  
A1H3W C06 H9   sing N N 35  
A1H3W C06 H10  sing N N 36  
A1H3W C07 H11  sing N N 37  
A1H3W C07 H12  sing N N 38  
A1H3W C09 H13  sing N N 39  
A1H3W C16 H14  sing N N 40  
A1H3W C16 H15  sing N N 41  
A1H3W C18 H16  sing N N 42  
A1H3W C19 H17  sing N N 43  
A1H3W C23 H18  sing N N 44  
A1H3W N05 H19  sing N N 45  
A1H3W N10 H20  sing N N 46  
ALA   N   CA   sing N N 47  
ALA   N   H    sing N N 48  
ALA   N   H2   sing N N 49  
ALA   CA  C    sing N N 50  
ALA   CA  CB   sing N N 51  
ALA   CA  HA   sing N N 52  
ALA   C   O    doub N N 53  
ALA   C   OXT  sing N N 54  
ALA   CB  HB1  sing N N 55  
ALA   CB  HB2  sing N N 56  
ALA   CB  HB3  sing N N 57  
ALA   OXT HXT  sing N N 58  
ARG   N   CA   sing N N 59  
ARG   N   H    sing N N 60  
ARG   N   H2   sing N N 61  
ARG   CA  C    sing N N 62  
ARG   CA  CB   sing N N 63  
ARG   CA  HA   sing N N 64  
ARG   C   O    doub N N 65  
ARG   C   OXT  sing N N 66  
ARG   CB  CG   sing N N 67  
ARG   CB  HB2  sing N N 68  
ARG   CB  HB3  sing N N 69  
ARG   CG  CD   sing N N 70  
ARG   CG  HG2  sing N N 71  
ARG   CG  HG3  sing N N 72  
ARG   CD  NE   sing N N 73  
ARG   CD  HD2  sing N N 74  
ARG   CD  HD3  sing N N 75  
ARG   NE  CZ   sing N N 76  
ARG   NE  HE   sing N N 77  
ARG   CZ  NH1  sing N N 78  
ARG   CZ  NH2  doub N N 79  
ARG   NH1 HH11 sing N N 80  
ARG   NH1 HH12 sing N N 81  
ARG   NH2 HH21 sing N N 82  
ARG   NH2 HH22 sing N N 83  
ARG   OXT HXT  sing N N 84  
ASN   N   CA   sing N N 85  
ASN   N   H    sing N N 86  
ASN   N   H2   sing N N 87  
ASN   CA  C    sing N N 88  
ASN   CA  CB   sing N N 89  
ASN   CA  HA   sing N N 90  
ASN   C   O    doub N N 91  
ASN   C   OXT  sing N N 92  
ASN   CB  CG   sing N N 93  
ASN   CB  HB2  sing N N 94  
ASN   CB  HB3  sing N N 95  
ASN   CG  OD1  doub N N 96  
ASN   CG  ND2  sing N N 97  
ASN   ND2 HD21 sing N N 98  
ASN   ND2 HD22 sing N N 99  
ASN   OXT HXT  sing N N 100 
ASP   N   CA   sing N N 101 
ASP   N   H    sing N N 102 
ASP   N   H2   sing N N 103 
ASP   CA  C    sing N N 104 
ASP   CA  CB   sing N N 105 
ASP   CA  HA   sing N N 106 
ASP   C   O    doub N N 107 
ASP   C   OXT  sing N N 108 
ASP   CB  CG   sing N N 109 
ASP   CB  HB2  sing N N 110 
ASP   CB  HB3  sing N N 111 
ASP   CG  OD1  doub N N 112 
ASP   CG  OD2  sing N N 113 
ASP   OD2 HD2  sing N N 114 
ASP   OXT HXT  sing N N 115 
CYS   N   CA   sing N N 116 
CYS   N   H    sing N N 117 
CYS   N   H2   sing N N 118 
CYS   CA  C    sing N N 119 
CYS   CA  CB   sing N N 120 
CYS   CA  HA   sing N N 121 
CYS   C   O    doub N N 122 
CYS   C   OXT  sing N N 123 
CYS   CB  SG   sing N N 124 
CYS   CB  HB2  sing N N 125 
CYS   CB  HB3  sing N N 126 
CYS   SG  HG   sing N N 127 
CYS   OXT HXT  sing N N 128 
GLN   N   CA   sing N N 129 
GLN   N   H    sing N N 130 
GLN   N   H2   sing N N 131 
GLN   CA  C    sing N N 132 
GLN   CA  CB   sing N N 133 
GLN   CA  HA   sing N N 134 
GLN   C   O    doub N N 135 
GLN   C   OXT  sing N N 136 
GLN   CB  CG   sing N N 137 
GLN   CB  HB2  sing N N 138 
GLN   CB  HB3  sing N N 139 
GLN   CG  CD   sing N N 140 
GLN   CG  HG2  sing N N 141 
GLN   CG  HG3  sing N N 142 
GLN   CD  OE1  doub N N 143 
GLN   CD  NE2  sing N N 144 
GLN   NE2 HE21 sing N N 145 
GLN   NE2 HE22 sing N N 146 
GLN   OXT HXT  sing N N 147 
GLU   N   CA   sing N N 148 
GLU   N   H    sing N N 149 
GLU   N   H2   sing N N 150 
GLU   CA  C    sing N N 151 
GLU   CA  CB   sing N N 152 
GLU   CA  HA   sing N N 153 
GLU   C   O    doub N N 154 
GLU   C   OXT  sing N N 155 
GLU   CB  CG   sing N N 156 
GLU   CB  HB2  sing N N 157 
GLU   CB  HB3  sing N N 158 
GLU   CG  CD   sing N N 159 
GLU   CG  HG2  sing N N 160 
GLU   CG  HG3  sing N N 161 
GLU   CD  OE1  doub N N 162 
GLU   CD  OE2  sing N N 163 
GLU   OE2 HE2  sing N N 164 
GLU   OXT HXT  sing N N 165 
GLY   N   CA   sing N N 166 
GLY   N   H    sing N N 167 
GLY   N   H2   sing N N 168 
GLY   CA  C    sing N N 169 
GLY   CA  HA2  sing N N 170 
GLY   CA  HA3  sing N N 171 
GLY   C   O    doub N N 172 
GLY   C   OXT  sing N N 173 
GLY   OXT HXT  sing N N 174 
HIS   N   CA   sing N N 175 
HIS   N   H    sing N N 176 
HIS   N   H2   sing N N 177 
HIS   CA  C    sing N N 178 
HIS   CA  CB   sing N N 179 
HIS   CA  HA   sing N N 180 
HIS   C   O    doub N N 181 
HIS   C   OXT  sing N N 182 
HIS   CB  CG   sing N N 183 
HIS   CB  HB2  sing N N 184 
HIS   CB  HB3  sing N N 185 
HIS   CG  ND1  sing Y N 186 
HIS   CG  CD2  doub Y N 187 
HIS   ND1 CE1  doub Y N 188 
HIS   ND1 HD1  sing N N 189 
HIS   CD2 NE2  sing Y N 190 
HIS   CD2 HD2  sing N N 191 
HIS   CE1 NE2  sing Y N 192 
HIS   CE1 HE1  sing N N 193 
HIS   NE2 HE2  sing N N 194 
HIS   OXT HXT  sing N N 195 
HOH   O   H1   sing N N 196 
HOH   O   H2   sing N N 197 
ILE   N   CA   sing N N 198 
ILE   N   H    sing N N 199 
ILE   N   H2   sing N N 200 
ILE   CA  C    sing N N 201 
ILE   CA  CB   sing N N 202 
ILE   CA  HA   sing N N 203 
ILE   C   O    doub N N 204 
ILE   C   OXT  sing N N 205 
ILE   CB  CG1  sing N N 206 
ILE   CB  CG2  sing N N 207 
ILE   CB  HB   sing N N 208 
ILE   CG1 CD1  sing N N 209 
ILE   CG1 HG12 sing N N 210 
ILE   CG1 HG13 sing N N 211 
ILE   CG2 HG21 sing N N 212 
ILE   CG2 HG22 sing N N 213 
ILE   CG2 HG23 sing N N 214 
ILE   CD1 HD11 sing N N 215 
ILE   CD1 HD12 sing N N 216 
ILE   CD1 HD13 sing N N 217 
ILE   OXT HXT  sing N N 218 
LEU   N   CA   sing N N 219 
LEU   N   H    sing N N 220 
LEU   N   H2   sing N N 221 
LEU   CA  C    sing N N 222 
LEU   CA  CB   sing N N 223 
LEU   CA  HA   sing N N 224 
LEU   C   O    doub N N 225 
LEU   C   OXT  sing N N 226 
LEU   CB  CG   sing N N 227 
LEU   CB  HB2  sing N N 228 
LEU   CB  HB3  sing N N 229 
LEU   CG  CD1  sing N N 230 
LEU   CG  CD2  sing N N 231 
LEU   CG  HG   sing N N 232 
LEU   CD1 HD11 sing N N 233 
LEU   CD1 HD12 sing N N 234 
LEU   CD1 HD13 sing N N 235 
LEU   CD2 HD21 sing N N 236 
LEU   CD2 HD22 sing N N 237 
LEU   CD2 HD23 sing N N 238 
LEU   OXT HXT  sing N N 239 
LYS   N   CA   sing N N 240 
LYS   N   H    sing N N 241 
LYS   N   H2   sing N N 242 
LYS   CA  C    sing N N 243 
LYS   CA  CB   sing N N 244 
LYS   CA  HA   sing N N 245 
LYS   C   O    doub N N 246 
LYS   C   OXT  sing N N 247 
LYS   CB  CG   sing N N 248 
LYS   CB  HB2  sing N N 249 
LYS   CB  HB3  sing N N 250 
LYS   CG  CD   sing N N 251 
LYS   CG  HG2  sing N N 252 
LYS   CG  HG3  sing N N 253 
LYS   CD  CE   sing N N 254 
LYS   CD  HD2  sing N N 255 
LYS   CD  HD3  sing N N 256 
LYS   CE  NZ   sing N N 257 
LYS   CE  HE2  sing N N 258 
LYS   CE  HE3  sing N N 259 
LYS   NZ  HZ1  sing N N 260 
LYS   NZ  HZ2  sing N N 261 
LYS   NZ  HZ3  sing N N 262 
LYS   OXT HXT  sing N N 263 
MET   N   CA   sing N N 264 
MET   N   H    sing N N 265 
MET   N   H2   sing N N 266 
MET   CA  C    sing N N 267 
MET   CA  CB   sing N N 268 
MET   CA  HA   sing N N 269 
MET   C   O    doub N N 270 
MET   C   OXT  sing N N 271 
MET   CB  CG   sing N N 272 
MET   CB  HB2  sing N N 273 
MET   CB  HB3  sing N N 274 
MET   CG  SD   sing N N 275 
MET   CG  HG2  sing N N 276 
MET   CG  HG3  sing N N 277 
MET   SD  CE   sing N N 278 
MET   CE  HE1  sing N N 279 
MET   CE  HE2  sing N N 280 
MET   CE  HE3  sing N N 281 
MET   OXT HXT  sing N N 282 
PHE   N   CA   sing N N 283 
PHE   N   H    sing N N 284 
PHE   N   H2   sing N N 285 
PHE   CA  C    sing N N 286 
PHE   CA  CB   sing N N 287 
PHE   CA  HA   sing N N 288 
PHE   C   O    doub N N 289 
PHE   C   OXT  sing N N 290 
PHE   CB  CG   sing N N 291 
PHE   CB  HB2  sing N N 292 
PHE   CB  HB3  sing N N 293 
PHE   CG  CD1  doub Y N 294 
PHE   CG  CD2  sing Y N 295 
PHE   CD1 CE1  sing Y N 296 
PHE   CD1 HD1  sing N N 297 
PHE   CD2 CE2  doub Y N 298 
PHE   CD2 HD2  sing N N 299 
PHE   CE1 CZ   doub Y N 300 
PHE   CE1 HE1  sing N N 301 
PHE   CE2 CZ   sing Y N 302 
PHE   CE2 HE2  sing N N 303 
PHE   CZ  HZ   sing N N 304 
PHE   OXT HXT  sing N N 305 
PRO   N   CA   sing N N 306 
PRO   N   CD   sing N N 307 
PRO   N   H    sing N N 308 
PRO   CA  C    sing N N 309 
PRO   CA  CB   sing N N 310 
PRO   CA  HA   sing N N 311 
PRO   C   O    doub N N 312 
PRO   C   OXT  sing N N 313 
PRO   CB  CG   sing N N 314 
PRO   CB  HB2  sing N N 315 
PRO   CB  HB3  sing N N 316 
PRO   CG  CD   sing N N 317 
PRO   CG  HG2  sing N N 318 
PRO   CG  HG3  sing N N 319 
PRO   CD  HD2  sing N N 320 
PRO   CD  HD3  sing N N 321 
PRO   OXT HXT  sing N N 322 
SER   N   CA   sing N N 323 
SER   N   H    sing N N 324 
SER   N   H2   sing N N 325 
SER   CA  C    sing N N 326 
SER   CA  CB   sing N N 327 
SER   CA  HA   sing N N 328 
SER   C   O    doub N N 329 
SER   C   OXT  sing N N 330 
SER   CB  OG   sing N N 331 
SER   CB  HB2  sing N N 332 
SER   CB  HB3  sing N N 333 
SER   OG  HG   sing N N 334 
SER   OXT HXT  sing N N 335 
THR   N   CA   sing N N 336 
THR   N   H    sing N N 337 
THR   N   H2   sing N N 338 
THR   CA  C    sing N N 339 
THR   CA  CB   sing N N 340 
THR   CA  HA   sing N N 341 
THR   C   O    doub N N 342 
THR   C   OXT  sing N N 343 
THR   CB  OG1  sing N N 344 
THR   CB  CG2  sing N N 345 
THR   CB  HB   sing N N 346 
THR   OG1 HG1  sing N N 347 
THR   CG2 HG21 sing N N 348 
THR   CG2 HG22 sing N N 349 
THR   CG2 HG23 sing N N 350 
THR   OXT HXT  sing N N 351 
TRP   N   CA   sing N N 352 
TRP   N   H    sing N N 353 
TRP   N   H2   sing N N 354 
TRP   CA  C    sing N N 355 
TRP   CA  CB   sing N N 356 
TRP   CA  HA   sing N N 357 
TRP   C   O    doub N N 358 
TRP   C   OXT  sing N N 359 
TRP   CB  CG   sing N N 360 
TRP   CB  HB2  sing N N 361 
TRP   CB  HB3  sing N N 362 
TRP   CG  CD1  doub Y N 363 
TRP   CG  CD2  sing Y N 364 
TRP   CD1 NE1  sing Y N 365 
TRP   CD1 HD1  sing N N 366 
TRP   CD2 CE2  doub Y N 367 
TRP   CD2 CE3  sing Y N 368 
TRP   NE1 CE2  sing Y N 369 
TRP   NE1 HE1  sing N N 370 
TRP   CE2 CZ2  sing Y N 371 
TRP   CE3 CZ3  doub Y N 372 
TRP   CE3 HE3  sing N N 373 
TRP   CZ2 CH2  doub Y N 374 
TRP   CZ2 HZ2  sing N N 375 
TRP   CZ3 CH2  sing Y N 376 
TRP   CZ3 HZ3  sing N N 377 
TRP   CH2 HH2  sing N N 378 
TRP   OXT HXT  sing N N 379 
TYR   N   CA   sing N N 380 
TYR   N   H    sing N N 381 
TYR   N   H2   sing N N 382 
TYR   CA  C    sing N N 383 
TYR   CA  CB   sing N N 384 
TYR   CA  HA   sing N N 385 
TYR   C   O    doub N N 386 
TYR   C   OXT  sing N N 387 
TYR   CB  CG   sing N N 388 
TYR   CB  HB2  sing N N 389 
TYR   CB  HB3  sing N N 390 
TYR   CG  CD1  doub Y N 391 
TYR   CG  CD2  sing Y N 392 
TYR   CD1 CE1  sing Y N 393 
TYR   CD1 HD1  sing N N 394 
TYR   CD2 CE2  doub Y N 395 
TYR   CD2 HD2  sing N N 396 
TYR   CE1 CZ   doub Y N 397 
TYR   CE1 HE1  sing N N 398 
TYR   CE2 CZ   sing Y N 399 
TYR   CE2 HE2  sing N N 400 
TYR   CZ  OH   sing N N 401 
TYR   OH  HH   sing N N 402 
TYR   OXT HXT  sing N N 403 
VAL   N   CA   sing N N 404 
VAL   N   H    sing N N 405 
VAL   N   H2   sing N N 406 
VAL   CA  C    sing N N 407 
VAL   CA  CB   sing N N 408 
VAL   CA  HA   sing N N 409 
VAL   C   O    doub N N 410 
VAL   C   OXT  sing N N 411 
VAL   CB  CG1  sing N N 412 
VAL   CB  CG2  sing N N 413 
VAL   CB  HB   sing N N 414 
VAL   CG1 HG11 sing N N 415 
VAL   CG1 HG12 sing N N 416 
VAL   CG1 HG13 sing N N 417 
VAL   CG2 HG21 sing N N 418 
VAL   CG2 HG22 sing N N 419 
VAL   CG2 HG23 sing N N 420 
VAL   OXT HXT  sing N N 421 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6S60 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8RXV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.008750 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003424 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.016289 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013416 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY   A 1 7   ? 29.264 60.189 -9.788  1.00 75.04  ? 222 GLY   A N   1 
ATOM   2    C CA  . GLY   A 1 7   ? 30.066 59.080 -9.297  1.00 70.56  ? 222 GLY   A CA  1 
ATOM   3    C C   . GLY   A 1 7   ? 29.845 57.776 -10.048 1.00 70.85  ? 222 GLY   A C   1 
ATOM   4    O O   . GLY   A 1 7   ? 28.803 57.569 -10.664 1.00 71.37  ? 222 GLY   A O   1 
ATOM   5    N N   . LEU   A 1 8   ? 30.834 56.890 -10.003 1.00 70.07  ? 223 LEU   A N   1 
ATOM   6    C CA  . LEU   A 1 8   ? 30.671 55.519 -10.469 1.00 70.51  ? 223 LEU   A CA  1 
ATOM   7    C C   . LEU   A 1 8   ? 30.381 54.678 -9.233  1.00 69.22  ? 223 LEU   A C   1 
ATOM   8    O O   . LEU   A 1 8   ? 31.283 54.228 -8.528  1.00 67.29  ? 223 LEU   A O   1 
ATOM   9    C CB  . LEU   A 1 8   ? 31.903 55.046 -11.240 1.00 68.45  ? 223 LEU   A CB  1 
ATOM   10   C CG  . LEU   A 1 8   ? 31.695 53.900 -12.233 1.00 69.46  ? 223 LEU   A CG  1 
ATOM   11   C CD1 . LEU   A 1 8   ? 32.976 53.571 -13.034 1.00 66.91  ? 223 LEU   A CD1 1 
ATOM   12   C CD2 . LEU   A 1 8   ? 31.198 52.631 -11.528 1.00 67.52  ? 223 LEU   A CD2 1 
ATOM   13   N N   . GLY   A 1 9   ? 29.104 54.472 -8.969  1.00 69.38  ? 224 GLY   A N   1 
ATOM   14   C CA  . GLY   A 1 9   ? 28.726 53.666 -7.843  1.00 69.18  ? 224 GLY   A CA  1 
ATOM   15   C C   . GLY   A 1 9   ? 27.254 53.819 -7.584  1.00 69.01  ? 224 GLY   A C   1 
ATOM   16   O O   . GLY   A 1 9   ? 26.568 54.655 -8.175  1.00 69.93  ? 224 GLY   A O   1 
ATOM   17   N N   . THR   A 1 10  ? 26.777 53.001 -6.676  1.00 69.68  ? 225 THR   A N   1 
ATOM   18   C CA  . THR   A 1 10  ? 25.389 53.032 -6.264  1.00 69.61  ? 225 THR   A CA  1 
ATOM   19   C C   . THR   A 1 10  ? 25.305 53.417 -4.794  1.00 68.40  ? 225 THR   A C   1 
ATOM   20   O O   . THR   A 1 10  ? 26.293 53.819 -4.177  1.00 67.41  ? 225 THR   A O   1 
ATOM   21   C CB  . THR   A 1 10  ? 24.755 51.680 -6.549  1.00 68.63  ? 225 THR   A CB  1 
ATOM   22   O OG1 . THR   A 1 10  ? 25.448 50.699 -5.781  1.00 69.44  ? 225 THR   A OG1 1 
ATOM   23   C CG2 . THR   A 1 10  ? 24.921 51.344 -8.045  1.00 66.95  ? 225 THR   A CG2 1 
ATOM   24   N N   . ALA   A 1 11  ? 24.102 53.334 -4.240  1.00 68.38  ? 226 ALA   A N   1 
ATOM   25   C CA  . ALA   A 1 11  ? 23.980 53.519 -2.797  1.00 70.20  ? 226 ALA   A CA  1 
ATOM   26   C C   . ALA   A 1 11  ? 24.688 52.419 -2.019  1.00 70.98  ? 226 ALA   A C   1 
ATOM   27   O O   . ALA   A 1 11  ? 24.917 52.584 -0.813  1.00 71.67  ? 226 ALA   A O   1 
ATOM   28   C CB  . ALA   A 1 11  ? 22.509 53.567 -2.366  1.00 68.18  ? 226 ALA   A CB  1 
ATOM   29   N N   . ARG   A 1 12  ? 25.022 51.301 -2.674  1.00 68.20  ? 227 ARG   A N   1 
ATOM   30   C CA  . ARG   A 1 12  ? 25.535 50.109 -2.003  1.00 72.10  ? 227 ARG   A CA  1 
ATOM   31   C C   . ARG   A 1 12  ? 27.032 49.922 -2.148  1.00 73.70  ? 227 ARG   A C   1 
ATOM   32   O O   . ARG   A 1 12  ? 27.661 49.309 -1.277  1.00 67.32  ? 227 ARG   A O   1 
ATOM   33   C CB  . ARG   A 1 12  ? 24.834 48.850 -2.536  1.00 72.40  ? 227 ARG   A CB  1 
ATOM   34   C CG  . ARG   A 1 12  ? 23.320 48.846 -2.340  1.00 73.94  ? 227 ARG   A CG  1 
ATOM   35   C CD  . ARG   A 1 12  ? 22.775 47.421 -2.332  1.00 74.71  ? 227 ARG   A CD  1 
ATOM   36   N NE  . ARG   A 1 12  ? 23.656 46.527 -1.592  1.00 74.92  ? 227 ARG   A NE  1 
ATOM   37   C CZ  . ARG   A 1 12  ? 23.320 45.314 -1.192  1.00 76.54  ? 227 ARG   A CZ  1 
ATOM   38   N NH1 . ARG   A 1 12  ? 22.112 44.827 -1.416  1.00 78.83  ? 227 ARG   A NH1 1 
ATOM   39   N NH2 . ARG   A 1 12  ? 24.202 44.584 -0.513  1.00 77.88  ? 227 ARG   A NH2 1 
ATOM   40   N N   . LEU   A 1 13  ? 27.608 50.394 -3.250  1.00 72.08  ? 228 LEU   A N   1 
ATOM   41   C CA  . LEU   A 1 13  ? 29.022 50.193 -3.513  1.00 70.78  ? 228 LEU   A CA  1 
ATOM   42   C C   . LEU   A 1 13  ? 29.463 51.289 -4.461  1.00 69.59  ? 228 LEU   A C   1 
ATOM   43   O O   . LEU   A 1 13  ? 28.755 51.605 -5.426  1.00 66.93  ? 228 LEU   A O   1 
ATOM   44   C CB  . LEU   A 1 13  ? 29.277 48.814 -4.103  1.00 70.86  ? 228 LEU   A CB  1 
ATOM   45   C CG  . LEU   A 1 13  ? 30.734 48.398 -4.290  1.00 70.63  ? 228 LEU   A CG  1 
ATOM   46   C CD1 . LEU   A 1 13  ? 31.413 48.132 -2.942  1.00 69.35  ? 228 LEU   A CD1 1 
ATOM   47   C CD2 . LEU   A 1 13  ? 30.807 47.183 -5.220  1.00 68.15  ? 228 LEU   A CD2 1 
ATOM   48   N N   . GLN   A 1 14  ? 30.608 51.885 -4.174  1.00 69.11  ? 229 GLN   A N   1 
ATOM   49   C CA  . GLN   A 1 14  ? 31.078 53.034 -4.924  1.00 67.87  ? 229 GLN   A CA  1 
ATOM   50   C C   . GLN   A 1 14  ? 32.542 52.809 -5.226  1.00 68.92  ? 229 GLN   A C   1 
ATOM   51   O O   . GLN   A 1 14  ? 33.291 52.345 -4.360  1.00 67.81  ? 229 GLN   A O   1 
ATOM   52   C CB  . GLN   A 1 14  ? 30.904 54.319 -4.134  1.00 67.04  ? 229 GLN   A CB  1 
ATOM   53   C CG  . GLN   A 1 14  ? 29.473 54.595 -3.681  1.00 68.79  ? 229 GLN   A CG  1 
ATOM   54   C CD  . GLN   A 1 14  ? 29.301 54.443 -2.162  1.00 72.67  ? 229 GLN   A CD  1 
ATOM   55   O OE1 . GLN   A 1 14  ? 30.270 54.575 -1.412  1.00 73.22  ? 229 GLN   A OE1 1 
ATOM   56   N NE2 . GLN   A 1 14  ? 28.067 54.188 -1.706  1.00 68.86  ? 229 GLN   A NE2 1 
ATOM   57   N N   . LEU   A 1 15  ? 32.933 53.092 -6.469  1.00 68.68  ? 230 LEU   A N   1 
ATOM   58   C CA  . LEU   A 1 15  ? 34.331 52.996 -6.861  1.00 70.22  ? 230 LEU   A CA  1 
ATOM   59   C C   . LEU   A 1 15  ? 35.070 54.201 -6.309  1.00 69.82  ? 230 LEU   A C   1 
ATOM   60   O O   . LEU   A 1 15  ? 34.565 55.325 -6.360  1.00 70.30  ? 230 LEU   A O   1 
ATOM   61   C CB  . LEU   A 1 15  ? 34.471 52.955 -8.377  1.00 69.40  ? 230 LEU   A CB  1 
ATOM   62   C CG  . LEU   A 1 15  ? 35.927 52.953 -8.864  1.00 70.12  ? 230 LEU   A CG  1 
ATOM   63   C CD1 . LEU   A 1 15  ? 36.633 51.653 -8.516  1.00 69.15  ? 230 LEU   A CD1 1 
ATOM   64   C CD2 . LEU   A 1 15  ? 36.068 53.269 -10.359 1.00 69.29  ? 230 LEU   A CD2 1 
ATOM   65   N N   . VAL   A 1 16  ? 36.246 53.975 -5.750  1.00 68.33  ? 231 VAL   A N   1 
ATOM   66   C CA  . VAL   A 1 16  ? 37.020 55.051 -5.154  1.00 75.31  ? 231 VAL   A CA  1 
ATOM   67   C C   . VAL   A 1 16  ? 38.217 55.405 -6.015  1.00 75.05  ? 231 VAL   A C   1 
ATOM   68   O O   . VAL   A 1 16  ? 38.461 56.577 -6.321  1.00 74.82  ? 231 VAL   A O   1 
ATOM   69   C CB  . VAL   A 1 16  ? 37.441 54.657 -3.721  1.00 75.14  ? 231 VAL   A CB  1 
ATOM   70   C CG1 . VAL   A 1 16  ? 38.339 55.706 -3.108  1.00 74.14  ? 231 VAL   A CG1 1 
ATOM   71   C CG2 . VAL   A 1 16  ? 36.202 54.450 -2.895  1.00 73.86  ? 231 VAL   A CG2 1 
ATOM   72   N N   . GLU   A 1 17  ? 38.958 54.392 -6.436  1.00 73.46  ? 232 GLU   A N   1 
ATOM   73   C CA  . GLU   A 1 17  ? 40.141 54.616 -7.224  1.00 71.49  ? 232 GLU   A CA  1 
ATOM   74   C C   . GLU   A 1 17  ? 40.346 53.403 -8.105  1.00 72.92  ? 232 GLU   A C   1 
ATOM   75   O O   . GLU   A 1 17  ? 40.084 52.272 -7.686  1.00 68.65  ? 232 GLU   A O   1 
ATOM   76   C CB  . GLU   A 1 17  ? 41.369 54.872 -6.354  1.00 70.41  ? 232 GLU   A CB  1 
ATOM   77   C CG  . GLU   A 1 17  ? 42.338 55.778 -7.104  1.00 74.84  ? 232 GLU   A CG  1 
ATOM   78   C CD  . GLU   A 1 17  ? 43.502 56.236 -6.279  1.00 75.96  ? 232 GLU   A CD  1 
ATOM   79   O OE1 . GLU   A 1 17  ? 43.443 56.088 -5.042  1.00 77.44  ? 232 GLU   A OE1 1 
ATOM   80   O OE2 . GLU   A 1 17  ? 44.484 56.730 -6.876  1.00 76.31  ? 232 GLU   A OE2 1 
ATOM   81   N N   . PHE   A 1 18  ? 40.784 53.658 -9.333  1.00 67.03  ? 233 PHE   A N   1 
ATOM   82   C CA  . PHE   A 1 18  ? 41.123 52.597 -10.271 1.00 72.11  ? 233 PHE   A CA  1 
ATOM   83   C C   . PHE   A 1 18  ? 42.277 53.050 -11.150 1.00 70.41  ? 233 PHE   A C   1 
ATOM   84   O O   . PHE   A 1 18  ? 42.196 54.098 -11.804 1.00 63.57  ? 233 PHE   A O   1 
ATOM   85   C CB  . PHE   A 1 18  ? 39.950 52.198 -11.163 1.00 68.13  ? 233 PHE   A CB  1 
ATOM   86   C CG  . PHE   A 1 18  ? 40.338 51.190 -12.191 1.00 68.83  ? 233 PHE   A CG  1 
ATOM   87   C CD1 . PHE   A 1 18  ? 40.878 51.591 -13.405 1.00 68.38  ? 233 PHE   A CD1 1 
ATOM   88   C CD2 . PHE   A 1 18  ? 40.249 49.823 -11.910 1.00 68.24  ? 233 PHE   A CD2 1 
ATOM   89   C CE1 . PHE   A 1 18  ? 41.282 50.645 -14.349 1.00 66.32  ? 233 PHE   A CE1 1 
ATOM   90   C CE2 . PHE   A 1 18  ? 40.644 48.881 -12.836 1.00 67.48  ? 233 PHE   A CE2 1 
ATOM   91   C CZ  . PHE   A 1 18  ? 41.169 49.297 -14.069 1.00 66.77  ? 233 PHE   A CZ  1 
ATOM   92   N N   . SER   A 1 19  ? 43.341 52.263 -11.178 1.00 68.22  ? 234 SER   A N   1 
ATOM   93   C CA  . SER   A 1 19  ? 44.457 52.593 -12.034 1.00 72.04  ? 234 SER   A CA  1 
ATOM   94   C C   . SER   A 1 19  ? 45.035 51.330 -12.660 1.00 70.42  ? 234 SER   A C   1 
ATOM   95   O O   . SER   A 1 19  ? 44.889 50.222 -12.137 1.00 68.57  ? 234 SER   A O   1 
ATOM   96   C CB  . SER   A 1 19  ? 45.522 53.371 -11.256 1.00 71.05  ? 234 SER   A CB  1 
ATOM   97   O OG  . SER   A 1 19  ? 46.216 52.546 -10.348 1.00 72.79  ? 234 SER   A OG  1 
ATOM   98   N N   . ALA   A 1 20  ? 45.659 51.500 -13.818 1.00 71.56  ? 235 ALA   A N   1 
ATOM   99   C CA  . ALA   A 1 20  ? 46.505 50.457 -14.372 1.00 71.49  ? 235 ALA   A CA  1 
ATOM   100  C C   . ALA   A 1 20  ? 47.838 51.106 -14.688 1.00 68.94  ? 235 ALA   A C   1 
ATOM   101  O O   . ALA   A 1 20  ? 47.874 52.248 -15.144 1.00 66.66  ? 235 ALA   A O   1 
ATOM   102  C CB  . ALA   A 1 20  ? 45.859 49.811 -15.580 1.00 66.98  ? 235 ALA   A CB  1 
ATOM   103  N N   . PHE   A 1 21  ? 48.934 50.411 -14.399 1.00 71.51  ? 236 PHE   A N   1 
ATOM   104  C CA  . PHE   A 1 21  ? 50.218 51.095 -14.300 1.00 76.52  ? 236 PHE   A CA  1 
ATOM   105  C C   . PHE   A 1 21  ? 51.369 50.138 -14.578 1.00 77.59  ? 236 PHE   A C   1 
ATOM   106  O O   . PHE   A 1 21  ? 51.195 48.921 -14.642 1.00 76.54  ? 236 PHE   A O   1 
ATOM   107  C CB  . PHE   A 1 21  ? 50.371 51.737 -12.910 1.00 77.60  ? 236 PHE   A CB  1 
ATOM   108  C CG  . PHE   A 1 21  ? 50.213 50.763 -11.762 1.00 78.04  ? 236 PHE   A CG  1 
ATOM   109  C CD1 . PHE   A 1 21  ? 48.955 50.343 -11.353 1.00 77.37  ? 236 PHE   A CD1 1 
ATOM   110  C CD2 . PHE   A 1 21  ? 51.317 50.290 -11.078 1.00 82.41  ? 236 PHE   A CD2 1 
ATOM   111  C CE1 . PHE   A 1 21  ? 48.801 49.456 -10.290 1.00 77.45  ? 236 PHE   A CE1 1 
ATOM   112  C CE2 . PHE   A 1 21  ? 51.175 49.406 -10.005 1.00 83.62  ? 236 PHE   A CE2 1 
ATOM   113  C CZ  . PHE   A 1 21  ? 49.915 48.987 -9.611  1.00 80.41  ? 236 PHE   A CZ  1 
ATOM   114  N N   . VAL   A 1 22  ? 52.561 50.709 -14.741 1.00 79.04  ? 237 VAL   A N   1 
ATOM   115  C CA  . VAL   A 1 22  ? 53.804 49.945 -14.770 1.00 84.90  ? 237 VAL   A CA  1 
ATOM   116  C C   . VAL   A 1 22  ? 54.823 50.703 -13.937 1.00 88.43  ? 237 VAL   A C   1 
ATOM   117  O O   . VAL   A 1 22  ? 54.899 51.931 -14.020 1.00 87.41  ? 237 VAL   A O   1 
ATOM   118  C CB  . VAL   A 1 22  ? 54.311 49.696 -16.213 1.00 84.15  ? 237 VAL   A CB  1 
ATOM   119  C CG1 . VAL   A 1 22  ? 54.405 50.990 -17.027 1.00 81.75  ? 237 VAL   A CG1 1 
ATOM   120  C CG2 . VAL   A 1 22  ? 55.650 48.991 -16.185 1.00 88.19  ? 237 VAL   A CG2 1 
ATOM   121  N N   . GLU   A 1 23  ? 55.535 49.919 -13.124 1.00 91.07  ? 238 GLU   A N   1 
ATOM   122  C CA  . GLU   A 1 23  ? 56.399 50.376 -12.047 1.00 96.12  ? 238 GLU   A CA  1 
ATOM   123  C C   . GLU   A 1 23  ? 57.619 51.113 -12.551 1.00 102.30 ? 238 GLU   A C   1 
ATOM   124  O O   . GLU   A 1 23  ? 57.557 52.324 -12.765 1.00 102.54 ? 238 GLU   A O   1 
ATOM   125  C CB  . GLU   A 1 23  ? 56.828 49.195 -11.172 1.00 97.28  ? 238 GLU   A CB  1 
ATOM   126  C CG  . GLU   A 1 23  ? 56.770 49.475 -9.679  1.00 92.99  ? 238 GLU   A CG  1 
ATOM   127  C CD  . GLU   A 1 23  ? 55.434 49.099 -9.068  1.00 93.87  ? 238 GLU   A CD  1 
ATOM   128  O OE1 . GLU   A 1 23  ? 55.072 47.905 -9.115  1.00 96.57  ? 238 GLU   A OE1 1 
ATOM   129  O OE2 . GLU   A 1 23  ? 54.746 49.998 -8.540  1.00 94.05  ? 238 GLU   A OE2 1 
ATOM   130  N N   . PRO   A 1 24  ? 58.742 50.420 -12.727 1.00 116.62 ? 239 PRO   A N   1 
ATOM   131  C CA  . PRO   A 1 24  ? 58.937 48.975 -12.573 1.00 114.58 ? 239 PRO   A CA  1 
ATOM   132  C C   . PRO   A 1 24  ? 59.584 48.656 -11.220 1.00 116.74 ? 239 PRO   A C   1 
ATOM   133  O O   . PRO   A 1 24  ? 59.286 49.347 -10.255 1.00 118.64 ? 239 PRO   A O   1 
ATOM   134  C CB  . PRO   A 1 24  ? 59.851 48.658 -13.765 1.00 117.54 ? 239 PRO   A CB  1 
ATOM   135  C CG  . PRO   A 1 24  ? 60.747 49.904 -13.880 1.00 114.99 ? 239 PRO   A CG  1 
ATOM   136  C CD  . PRO   A 1 24  ? 60.002 51.043 -13.180 1.00 116.77 ? 239 PRO   A CD  1 
ATOM   137  N N   . PRO   A 1 25  ? 60.478 47.659 -11.062 1.00 114.53 ? 240 PRO   A N   1 
ATOM   138  C CA  . PRO   A 1 25  ? 61.016 47.502 -9.706  1.00 115.21 ? 240 PRO   A CA  1 
ATOM   139  C C   . PRO   A 1 25  ? 62.209 48.420 -9.400  1.00 115.68 ? 240 PRO   A C   1 
ATOM   140  O O   . PRO   A 1 25  ? 62.302 48.991 -8.298  1.00 114.16 ? 240 PRO   A O   1 
ATOM   141  C CB  . PRO   A 1 25  ? 61.444 46.027 -9.675  1.00 114.98 ? 240 PRO   A CB  1 
ATOM   142  C CG  . PRO   A 1 25  ? 61.358 45.529 -11.118 1.00 112.81 ? 240 PRO   A CG  1 
ATOM   143  C CD  . PRO   A 1 25  ? 61.118 46.709 -11.987 1.00 112.87 ? 240 PRO   A CD  1 
ATOM   144  N N   . ARG   A 1 33  ? 55.979 55.142 -10.964 1.00 86.04  ? 248 ARG   A N   1 
ATOM   145  C CA  . ARG   A 1 33  ? 54.781 54.629 -11.619 1.00 81.14  ? 248 ARG   A CA  1 
ATOM   146  C C   . ARG   A 1 33  ? 54.402 55.443 -12.853 1.00 79.54  ? 248 ARG   A C   1 
ATOM   147  O O   . ARG   A 1 33  ? 54.472 56.674 -12.840 1.00 81.04  ? 248 ARG   A O   1 
ATOM   148  C CB  . ARG   A 1 33  ? 53.596 54.609 -10.649 1.00 81.15  ? 248 ARG   A CB  1 
ATOM   149  C CG  . ARG   A 1 33  ? 53.197 53.227 -10.133 1.00 83.97  ? 248 ARG   A CG  1 
ATOM   150  C CD  . ARG   A 1 33  ? 51.725 53.174 -9.678  1.00 77.75  ? 248 ARG   A CD  1 
ATOM   151  N NE  . ARG   A 1 33  ? 51.535 52.156 -8.651  1.00 81.64  ? 248 ARG   A NE  1 
ATOM   152  C CZ  . ARG   A 1 33  ? 50.569 52.165 -7.737  1.00 81.32  ? 248 ARG   A CZ  1 
ATOM   153  N NH1 . ARG   A 1 33  ? 49.604 53.075 -7.758  1.00 81.75  ? 248 ARG   A NH1 1 
ATOM   154  N NH2 . ARG   A 1 33  ? 50.585 51.252 -6.763  1.00 82.16  ? 248 ARG   A NH2 1 
ATOM   155  N N   . HIS   A 1 34  ? 54.026 54.744 -13.930 1.00 79.79  ? 249 HIS   A N   1 
ATOM   156  C CA  . HIS   A 1 34  ? 53.327 55.333 -15.063 1.00 77.91  ? 249 HIS   A CA  1 
ATOM   157  C C   . HIS   A 1 34  ? 51.929 54.730 -15.123 1.00 74.69  ? 249 HIS   A C   1 
ATOM   158  O O   . HIS   A 1 34  ? 51.784 53.503 -15.186 1.00 75.90  ? 249 HIS   A O   1 
ATOM   159  C CB  . HIS   A 1 34  ? 54.078 55.088 -16.394 1.00 78.27  ? 249 HIS   A CB  1 
ATOM   160  C CG  . HIS   A 1 34  ? 53.284 55.443 -17.619 1.00 75.73  ? 249 HIS   A CG  1 
ATOM   161  N ND1 . HIS   A 1 34  ? 53.257 56.720 -18.146 1.00 76.37  ? 249 HIS   A ND1 1 
ATOM   162  C CD2 . HIS   A 1 34  ? 52.484 54.693 -18.416 1.00 74.19  ? 249 HIS   A CD2 1 
ATOM   163  C CE1 . HIS   A 1 34  ? 52.476 56.739 -19.211 1.00 75.19  ? 249 HIS   A CE1 1 
ATOM   164  N NE2 . HIS   A 1 34  ? 51.990 55.524 -19.393 1.00 74.63  ? 249 HIS   A NE2 1 
ATOM   165  N N   . LEU   A 1 35  ? 50.904 55.584 -15.119 1.00 72.14  ? 250 LEU   A N   1 
ATOM   166  C CA  . LEU   A 1 35  ? 49.518 55.141 -15.218 1.00 71.62  ? 250 LEU   A CA  1 
ATOM   167  C C   . LEU   A 1 35  ? 49.042 55.181 -16.661 1.00 70.85  ? 250 LEU   A C   1 
ATOM   168  O O   . LEU   A 1 35  ? 49.149 56.218 -17.313 1.00 70.37  ? 250 LEU   A O   1 
ATOM   169  C CB  . LEU   A 1 35  ? 48.603 56.001 -14.341 1.00 69.82  ? 250 LEU   A CB  1 
ATOM   170  C CG  . LEU   A 1 35  ? 49.026 56.191 -12.875 1.00 68.81  ? 250 LEU   A CG  1 
ATOM   171  C CD1 . LEU   A 1 35  ? 48.689 57.596 -12.287 1.00 70.61  ? 250 LEU   A CD1 1 
ATOM   172  C CD2 . LEU   A 1 35  ? 48.434 55.080 -12.039 1.00 66.74  ? 250 LEU   A CD2 1 
ATOM   173  N N   . PHE   A 1 36  ? 48.502 54.058 -17.152 1.00 67.99  ? 251 PHE   A N   1 
ATOM   174  C CA  . PHE   A 1 36  ? 47.880 54.072 -18.476 1.00 69.22  ? 251 PHE   A CA  1 
ATOM   175  C C   . PHE   A 1 36  ? 46.471 54.632 -18.400 1.00 68.04  ? 251 PHE   A C   1 
ATOM   176  O O   . PHE   A 1 36  ? 46.044 55.366 -19.291 1.00 65.84  ? 251 PHE   A O   1 
ATOM   177  C CB  . PHE   A 1 36  ? 47.829 52.669 -19.092 1.00 68.14  ? 251 PHE   A CB  1 
ATOM   178  C CG  . PHE   A 1 36  ? 49.119 51.898 -18.978 1.00 71.45  ? 251 PHE   A CG  1 
ATOM   179  C CD1 . PHE   A 1 36  ? 50.217 52.225 -19.765 1.00 69.71  ? 251 PHE   A CD1 1 
ATOM   180  C CD2 . PHE   A 1 36  ? 49.227 50.842 -18.077 1.00 70.05  ? 251 PHE   A CD2 1 
ATOM   181  C CE1 . PHE   A 1 36  ? 51.400 51.528 -19.645 1.00 72.52  ? 251 PHE   A CE1 1 
ATOM   182  C CE2 . PHE   A 1 36  ? 50.402 50.138 -17.953 1.00 71.23  ? 251 PHE   A CE2 1 
ATOM   183  C CZ  . PHE   A 1 36  ? 51.495 50.482 -18.735 1.00 74.73  ? 251 PHE   A CZ  1 
ATOM   184  N N   . VAL   A 1 37  ? 45.728 54.299 -17.349 1.00 66.05  ? 252 VAL   A N   1 
ATOM   185  C CA  . VAL   A 1 37  ? 44.423 54.902 -17.131 1.00 64.87  ? 252 VAL   A CA  1 
ATOM   186  C C   . VAL   A 1 37  ? 44.225 55.030 -15.634 1.00 64.31  ? 252 VAL   A C   1 
ATOM   187  O O   . VAL   A 1 37  ? 44.731 54.211 -14.858 1.00 64.48  ? 252 VAL   A O   1 
ATOM   188  C CB  . VAL   A 1 37  ? 43.300 54.068 -17.781 1.00 62.10  ? 252 VAL   A CB  1 
ATOM   189  C CG1 . VAL   A 1 37  ? 43.484 54.073 -19.325 1.00 64.20  ? 252 VAL   A CG1 1 
ATOM   190  C CG2 . VAL   A 1 37  ? 43.289 52.681 -17.185 1.00 63.59  ? 252 VAL   A CG2 1 
ATOM   191  N N   . HIS   A 1 38  ? 43.460 56.044 -15.229 1.00 63.85  ? 253 HIS   A N   1 
ATOM   192  C CA  . HIS   A 1 38  ? 43.342 56.374 -13.820 1.00 63.55  ? 253 HIS   A CA  1 
ATOM   193  C C   . HIS   A 1 38  ? 41.991 57.016 -13.530 1.00 66.32  ? 253 HIS   A C   1 
ATOM   194  O O   . HIS   A 1 38  ? 41.618 57.996 -14.183 1.00 65.76  ? 253 HIS   A O   1 
ATOM   195  C CB  . HIS   A 1 38  ? 44.485 57.308 -13.396 1.00 63.90  ? 253 HIS   A CB  1 
ATOM   196  C CG  . HIS   A 1 38  ? 44.477 57.636 -11.939 1.00 67.34  ? 253 HIS   A CG  1 
ATOM   197  N ND1 . HIS   A 1 38  ? 44.396 56.667 -10.956 1.00 69.76  ? 253 HIS   A ND1 1 
ATOM   198  C CD2 . HIS   A 1 38  ? 44.548 58.823 -11.290 1.00 71.28  ? 253 HIS   A CD2 1 
ATOM   199  C CE1 . HIS   A 1 38  ? 44.412 57.246 -9.766  1.00 72.33  ? 253 HIS   A CE1 1 
ATOM   200  N NE2 . HIS   A 1 38  ? 44.505 58.553 -9.939  1.00 74.20  ? 253 HIS   A NE2 1 
ATOM   201  N N   . ILE   A 1 39  ? 41.287 56.491 -12.521 1.00 67.49  ? 254 ILE   A N   1 
ATOM   202  C CA  . ILE   A 1 39  ? 40.059 57.087 -11.999 1.00 68.45  ? 254 ILE   A CA  1 
ATOM   203  C C   . ILE   A 1 39  ? 40.263 57.323 -10.513 1.00 71.04  ? 254 ILE   A C   1 
ATOM   204  O O   . ILE   A 1 39  ? 40.249 56.372 -9.718  1.00 71.48  ? 254 ILE   A O   1 
ATOM   205  C CB  . ILE   A 1 39  ? 38.836 56.187 -12.206 1.00 68.87  ? 254 ILE   A CB  1 
ATOM   206  C CG1 . ILE   A 1 39  ? 38.509 55.972 -13.689 1.00 66.26  ? 254 ILE   A CG1 1 
ATOM   207  C CG2 . ILE   A 1 39  ? 37.641 56.755 -11.442 1.00 67.65  ? 254 ILE   A CG2 1 
ATOM   208  C CD1 . ILE   A 1 39  ? 37.506 54.825 -13.886 1.00 63.82  ? 254 ILE   A CD1 1 
ATOM   209  N N   . SER   A 1 40  ? 40.407 58.579 -10.120 1.00 71.67  ? 255 SER   A N   1 
ATOM   210  C CA  . SER   A 1 40  ? 40.406 58.941 -8.715  1.00 75.41  ? 255 SER   A CA  1 
ATOM   211  C C   . SER   A 1 40  ? 39.069 59.572 -8.363  1.00 76.21  ? 255 SER   A C   1 
ATOM   212  O O   . SER   A 1 40  ? 38.492 60.321 -9.160  1.00 75.84  ? 255 SER   A O   1 
ATOM   213  C CB  . SER   A 1 40  ? 41.556 59.896 -8.386  1.00 79.21  ? 255 SER   A CB  1 
ATOM   214  O OG  . SER   A 1 40  ? 41.780 59.938 -6.973  1.00 85.42  ? 255 SER   A OG  1 
ATOM   215  N N   . GLN   A 1 41  ? 38.601 59.314 -7.152  1.00 75.20  ? 256 GLN   A N   1 
ATOM   216  C CA  . GLN   A 1 41  ? 37.329 59.904 -6.740  1.00 77.94  ? 256 GLN   A CA  1 
ATOM   217  C C   . GLN   A 1 41  ? 37.268 60.303 -5.259  1.00 76.63  ? 256 GLN   A C   1 
ATOM   218  O O   . GLN   A 1 41  ? 37.682 59.537 -4.377  1.00 75.65  ? 256 GLN   A O   1 
ATOM   219  C CB  . GLN   A 1 41  ? 36.200 58.922 -7.084  1.00 75.88  ? 256 GLN   A CB  1 
ATOM   220  C CG  . GLN   A 1 41  ? 35.952 58.816 -8.578  1.00 73.18  ? 256 GLN   A CG  1 
ATOM   221  C CD  . GLN   A 1 41  ? 34.760 57.930 -8.921  1.00 71.90  ? 256 GLN   A CD  1 
ATOM   222  O OE1 . GLN   A 1 41  ? 33.934 58.283 -9.764  1.00 72.21  ? 256 GLN   A OE1 1 
ATOM   223  N NE2 . GLN   A 1 41  ? 34.695 56.756 -8.308  1.00 72.86  ? 256 GLN   A NE2 1 
ATOM   224  N N   . PRO   A 1 49  ? 26.701 68.697 -12.588 1.00 117.26 ? 264 PRO   A N   1 
ATOM   225  C CA  . PRO   A 1 49  ? 26.789 67.810 -13.734 1.00 116.64 ? 264 PRO   A CA  1 
ATOM   226  C C   . PRO   A 1 49  ? 26.457 66.432 -13.247 1.00 114.11 ? 264 PRO   A C   1 
ATOM   227  O O   . PRO   A 1 49  ? 27.258 65.891 -12.491 1.00 112.17 ? 264 PRO   A O   1 
ATOM   228  C CB  . PRO   A 1 49  ? 28.268 67.860 -14.046 1.00 113.36 ? 264 PRO   A CB  1 
ATOM   229  C CG  . PRO   A 1 49  ? 28.916 68.016 -12.706 1.00 113.48 ? 264 PRO   A CG  1 
ATOM   230  C CD  . PRO   A 1 49  ? 27.896 68.557 -11.746 1.00 114.27 ? 264 PRO   A CD  1 
ATOM   231  N N   . PRO   A 1 50  ? 25.250 65.868 -13.682 1.00 117.60 ? 265 PRO   A N   1 
ATOM   232  C CA  . PRO   A 1 50  ? 25.010 64.539 -13.107 1.00 116.09 ? 265 PRO   A CA  1 
ATOM   233  C C   . PRO   A 1 50  ? 26.000 63.581 -13.733 1.00 111.07 ? 265 PRO   A C   1 
ATOM   234  O O   . PRO   A 1 50  ? 27.119 63.462 -13.264 1.00 109.76 ? 265 PRO   A O   1 
ATOM   235  C CB  . PRO   A 1 50  ? 23.567 64.198 -13.516 1.00 118.14 ? 265 PRO   A CB  1 
ATOM   236  C CG  . PRO   A 1 50  ? 22.941 65.469 -13.941 1.00 115.85 ? 265 PRO   A CG  1 
ATOM   237  C CD  . PRO   A 1 50  ? 24.064 66.154 -14.627 1.00 117.08 ? 265 PRO   A CD  1 
ATOM   238  N N   . LEU   A 1 51  ? 25.606 62.923 -14.801 1.00 105.41 ? 266 LEU   A N   1 
ATOM   239  C CA  . LEU   A 1 51  ? 26.500 62.038 -15.477 1.00 98.06  ? 266 LEU   A CA  1 
ATOM   240  C C   . LEU   A 1 51  ? 25.770 61.751 -16.721 1.00 96.66  ? 266 LEU   A C   1 
ATOM   241  O O   . LEU   A 1 51  ? 24.652 61.306 -16.671 1.00 97.07  ? 266 LEU   A O   1 
ATOM   242  C CB  . LEU   A 1 51  ? 26.646 60.762 -14.678 1.00 92.93  ? 266 LEU   A CB  1 
ATOM   243  C CG  . LEU   A 1 51  ? 28.019 60.138 -14.511 1.00 85.60  ? 266 LEU   A CG  1 
ATOM   244  C CD1 . LEU   A 1 51  ? 28.989 61.105 -13.877 1.00 84.88  ? 266 LEU   A CD1 1 
ATOM   245  C CD2 . LEU   A 1 51  ? 27.896 58.897 -13.660 1.00 82.40  ? 266 LEU   A CD2 1 
ATOM   246  N N   . GLU   A 1 52  ? 26.384 62.004 -17.857 1.00 89.68  ? 267 GLU   A N   1 
ATOM   247  C CA  . GLU   A 1 52  ? 25.715 61.775 -19.112 1.00 87.24  ? 267 GLU   A CA  1 
ATOM   248  C C   . GLU   A 1 52  ? 25.296 60.351 -19.159 1.00 83.32  ? 267 GLU   A C   1 
ATOM   249  O O   . GLU   A 1 52  ? 25.687 59.581 -18.330 1.00 83.39  ? 267 GLU   A O   1 
ATOM   250  C CB  . GLU   A 1 52  ? 26.647 62.074 -20.262 1.00 87.75  ? 267 GLU   A CB  1 
ATOM   251  C CG  . GLU   A 1 52  ? 26.924 63.549 -20.428 1.00 88.96  ? 267 GLU   A CG  1 
ATOM   252  C CD  . GLU   A 1 52  ? 27.543 63.850 -21.759 1.00 97.02  ? 267 GLU   A CD  1 
ATOM   253  O OE1 . GLU   A 1 52  ? 27.049 63.318 -22.768 1.00 105.31 ? 267 GLU   A OE1 1 
ATOM   254  O OE2 . GLU   A 1 52  ? 28.529 64.599 -21.792 1.00 101.10 ? 267 GLU   A OE2 1 
ATOM   255  N N   . SER   A 1 53  ? 24.494 60.008 -20.133 1.00 84.85  ? 268 SER   A N   1 
ATOM   256  C CA  . SER   A 1 53  ? 24.010 58.669 -20.238 1.00 82.92  ? 268 SER   A CA  1 
ATOM   257  C C   . SER   A 1 53  ? 24.244 58.172 -21.630 1.00 82.01  ? 268 SER   A C   1 
ATOM   258  O O   . SER   A 1 53  ? 24.238 58.932 -22.569 1.00 81.60  ? 268 SER   A O   1 
ATOM   259  C CB  . SER   A 1 53  ? 22.534 58.620 -19.878 1.00 82.84  ? 268 SER   A CB  1 
ATOM   260  O OG  . SER   A 1 53  ? 21.738 58.951 -20.983 1.00 84.91  ? 268 SER   A OG  1 
ATOM   261  N N   . VAL   A 1 54  ? 24.463 56.881 -21.749 1.00 81.55  ? 269 VAL   A N   1 
ATOM   262  C CA  . VAL   A 1 54  ? 24.653 56.237 -23.043 1.00 83.01  ? 269 VAL   A CA  1 
ATOM   263  C C   . VAL   A 1 54  ? 23.680 55.074 -23.143 1.00 85.66  ? 269 VAL   A C   1 
ATOM   264  O O   . VAL   A 1 54  ? 23.528 54.308 -22.187 1.00 85.68  ? 269 VAL   A O   1 
ATOM   265  C CB  . VAL   A 1 54  ? 26.102 55.735 -23.214 1.00 82.18  ? 269 VAL   A CB  1 
ATOM   266  C CG1 . VAL   A 1 54  ? 26.180 54.757 -24.364 1.00 84.70  ? 269 VAL   A CG1 1 
ATOM   267  C CG2 . VAL   A 1 54  ? 27.064 56.909 -23.428 1.00 78.35  ? 269 VAL   A CG2 1 
ATOM   268  N N   . ASP   A 1 55  ? 23.022 54.927 -24.290 1.00 88.01  ? 270 ASP   A N   1 
ATOM   269  C CA  . ASP   A 1 55  ? 22.097 53.811 -24.442 1.00 91.00  ? 270 ASP   A CA  1 
ATOM   270  C C   . ASP   A 1 55  ? 22.889 52.529 -24.665 1.00 93.52  ? 270 ASP   A C   1 
ATOM   271  O O   . ASP   A 1 55  ? 23.633 52.415 -25.644 1.00 95.06  ? 270 ASP   A O   1 
ATOM   272  C CB  . ASP   A 1 55  ? 21.110 54.045 -25.579 1.00 93.96  ? 270 ASP   A CB  1 
ATOM   273  C CG  . ASP   A 1 55  ? 20.031 52.962 -25.646 1.00 97.70  ? 270 ASP   A CG  1 
ATOM   274  O OD1 . ASP   A 1 55  ? 20.351 51.827 -26.054 1.00 98.27  ? 270 ASP   A OD1 1 
ATOM   275  O OD2 . ASP   A 1 55  ? 18.866 53.235 -25.276 1.00 99.67  ? 270 ASP   A OD2 1 
ATOM   276  N N   . VAL   A 1 56  ? 22.715 51.568 -23.753 1.00 96.31  ? 271 VAL   A N   1 
ATOM   277  C CA  . VAL   A 1 56  ? 23.497 50.335 -23.767 1.00 98.56  ? 271 VAL   A CA  1 
ATOM   278  C C   . VAL   A 1 56  ? 23.397 49.625 -25.115 1.00 102.09 ? 271 VAL   A C   1 
ATOM   279  O O   . VAL   A 1 56  ? 24.361 48.989 -25.564 1.00 103.48 ? 271 VAL   A O   1 
ATOM   280  C CB  . VAL   A 1 56  ? 23.045 49.434 -22.599 1.00 95.90  ? 271 VAL   A CB  1 
ATOM   281  C CG1 . VAL   A 1 56  ? 21.660 48.880 -22.871 1.00 98.26  ? 271 VAL   A CG1 1 
ATOM   282  C CG2 . VAL   A 1 56  ? 24.046 48.323 -22.340 1.00 94.44  ? 271 VAL   A CG2 1 
ATOM   283  N N   . ARG   A 1 57  ? 22.251 49.730 -25.792 1.00 98.02  ? 272 ARG   A N   1 
ATOM   284  C CA  . ARG   A 1 57  ? 22.096 49.062 -27.079 1.00 98.84  ? 272 ARG   A CA  1 
ATOM   285  C C   . ARG   A 1 57  ? 23.161 49.492 -28.079 1.00 99.34  ? 272 ARG   A C   1 
ATOM   286  O O   . ARG   A 1 57  ? 23.444 48.752 -29.028 1.00 100.66 ? 272 ARG   A O   1 
ATOM   287  C CB  . ARG   A 1 57  ? 20.698 49.324 -27.648 1.00 100.24 ? 272 ARG   A CB  1 
ATOM   288  C CG  . ARG   A 1 57  ? 19.570 49.255 -26.623 1.00 100.24 ? 272 ARG   A CG  1 
ATOM   289  C CD  . ARG   A 1 57  ? 18.267 48.803 -27.252 1.00 102.49 ? 272 ARG   A CD  1 
ATOM   290  N NE  . ARG   A 1 57  ? 17.108 49.399 -26.601 1.00 102.91 ? 272 ARG   A NE  1 
ATOM   291  C CZ  . ARG   A 1 57  ? 16.867 50.703 -26.557 1.00 106.45 ? 272 ARG   A CZ  1 
ATOM   292  N NH1 . ARG   A 1 57  ? 17.720 51.581 -27.065 1.00 105.31 ? 272 ARG   A NH1 1 
ATOM   293  N NH2 . ARG   A 1 57  ? 15.742 51.140 -25.992 1.00 107.34 ? 272 ARG   A NH2 1 
ATOM   294  N N   . GLN   A 1 58  ? 23.769 50.662 -27.879 1.00 100.52 ? 273 GLN   A N   1 
ATOM   295  C CA  . GLN   A 1 58  ? 24.779 51.139 -28.814 1.00 99.93  ? 273 GLN   A CA  1 
ATOM   296  C C   . GLN   A 1 58  ? 26.048 50.303 -28.753 1.00 100.38 ? 273 GLN   A C   1 
ATOM   297  O O   . GLN   A 1 58  ? 26.749 50.174 -29.763 1.00 100.50 ? 273 GLN   A O   1 
ATOM   298  C CB  . GLN   A 1 58  ? 25.098 52.601 -28.523 1.00 100.39 ? 273 GLN   A CB  1 
ATOM   299  C CG  . GLN   A 1 58  ? 23.857 53.457 -28.423 1.00 101.50 ? 273 GLN   A CG  1 
ATOM   300  C CD  . GLN   A 1 58  ? 23.925 54.688 -29.286 1.00 109.75 ? 273 GLN   A CD  1 
ATOM   301  O OE1 . GLN   A 1 58  ? 23.742 54.623 -30.503 1.00 114.22 ? 273 GLN   A OE1 1 
ATOM   302  N NE2 . GLN   A 1 58  ? 24.208 55.824 -28.664 1.00 107.04 ? 273 GLN   A NE2 1 
ATOM   303  N N   . ILE   A 1 59  ? 26.357 49.721 -27.595 1.00 102.92 ? 274 ILE   A N   1 
ATOM   304  C CA  . ILE   A 1 59  ? 27.592 48.972 -27.405 1.00 102.31 ? 274 ILE   A CA  1 
ATOM   305  C C   . ILE   A 1 59  ? 27.338 47.476 -27.264 1.00 104.71 ? 274 ILE   A C   1 
ATOM   306  O O   . ILE   A 1 59  ? 28.237 46.744 -26.842 1.00 105.06 ? 274 ILE   A O   1 
ATOM   307  C CB  . ILE   A 1 59  ? 28.382 49.490 -26.193 1.00 97.87  ? 274 ILE   A CB  1 
ATOM   308  C CG1 . ILE   A 1 59  ? 27.648 49.122 -24.905 1.00 96.05  ? 274 ILE   A CG1 1 
ATOM   309  C CG2 . ILE   A 1 59  ? 28.593 50.981 -26.277 1.00 95.68  ? 274 ILE   A CG2 1 
ATOM   310  C CD1 . ILE   A 1 59  ? 28.100 49.903 -23.692 1.00 90.17  ? 274 ILE   A CD1 1 
ATOM   311  N N   . TYR   A 1 60  ? 26.131 46.997 -27.588 1.00 108.13 ? 275 TYR   A N   1 
ATOM   312  C CA  . TYR   A 1 60  ? 25.846 45.566 -27.467 1.00 110.25 ? 275 TYR   A CA  1 
ATOM   313  C C   . TYR   A 1 60  ? 26.897 44.723 -28.189 1.00 110.04 ? 275 TYR   A C   1 
ATOM   314  O O   . TYR   A 1 60  ? 27.264 43.635 -27.724 1.00 108.29 ? 275 TYR   A O   1 
ATOM   315  C CB  . TYR   A 1 60  ? 24.458 45.257 -28.032 1.00 111.05 ? 275 TYR   A CB  1 
ATOM   316  C CG  . TYR   A 1 60  ? 23.318 45.259 -27.034 1.00 109.99 ? 275 TYR   A CG  1 
ATOM   317  C CD1 . TYR   A 1 60  ? 23.502 45.678 -25.716 1.00 108.45 ? 275 TYR   A CD1 1 
ATOM   318  C CD2 . TYR   A 1 60  ? 22.049 44.828 -27.415 1.00 112.63 ? 275 TYR   A CD2 1 
ATOM   319  C CE1 . TYR   A 1 60  ? 22.447 45.676 -24.811 1.00 109.34 ? 275 TYR   A CE1 1 
ATOM   320  C CE2 . TYR   A 1 60  ? 20.990 44.821 -26.522 1.00 115.63 ? 275 TYR   A CE2 1 
ATOM   321  C CZ  . TYR   A 1 60  ? 21.192 45.246 -25.220 1.00 115.57 ? 275 TYR   A CZ  1 
ATOM   322  O OH  . TYR   A 1 60  ? 20.135 45.235 -24.329 1.00 116.89 ? 275 TYR   A OH  1 
ATOM   323  N N   . ASP   A 1 61  ? 27.401 45.226 -29.323 1.00 106.79 ? 276 ASP   A N   1 
ATOM   324  C CA  . ASP   A 1 61  ? 28.267 44.470 -30.228 1.00 107.74 ? 276 ASP   A CA  1 
ATOM   325  C C   . ASP   A 1 61  ? 29.721 44.418 -29.780 1.00 105.97 ? 276 ASP   A C   1 
ATOM   326  O O   . ASP   A 1 61  ? 30.479 43.592 -30.305 1.00 104.39 ? 276 ASP   A O   1 
ATOM   327  C CB  . ASP   A 1 61  ? 28.194 45.078 -31.636 1.00 104.05 ? 276 ASP   A CB  1 
ATOM   328  C CG  . ASP   A 1 61  ? 28.743 46.496 -31.695 1.00 100.69 ? 276 ASP   A CG  1 
ATOM   329  O OD1 . ASP   A 1 61  ? 28.788 47.177 -30.653 1.00 102.04 ? 276 ASP   A OD1 1 
ATOM   330  O OD2 . ASP   A 1 61  ? 29.081 46.957 -32.800 1.00 102.48 ? 276 ASP   A OD2 1 
ATOM   331  N N   . LYS   A 1 62  ? 30.124 45.285 -28.849 1.00 99.78  ? 277 LYS   A N   1 
ATOM   332  C CA  . LYS   A 1 62  ? 31.482 45.294 -28.335 1.00 95.50  ? 277 LYS   A CA  1 
ATOM   333  C C   . LYS   A 1 62  ? 31.677 44.312 -27.197 1.00 94.52  ? 277 LYS   A C   1 
ATOM   334  O O   . LYS   A 1 62  ? 32.726 44.321 -26.543 1.00 90.61  ? 277 LYS   A O   1 
ATOM   335  C CB  . LYS   A 1 62  ? 31.869 46.709 -27.906 1.00 91.54  ? 277 LYS   A CB  1 
ATOM   336  C CG  . LYS   A 1 62  ? 31.628 47.758 -28.999 1.00 94.65  ? 277 LYS   A CG  1 
ATOM   337  C CD  . LYS   A 1 62  ? 32.898 48.580 -29.230 1.00 91.73  ? 277 LYS   A CD  1 
ATOM   338  C CE  . LYS   A 1 62  ? 32.630 50.061 -29.540 1.00 91.85  ? 277 LYS   A CE  1 
ATOM   339  N NZ  . LYS   A 1 62  ? 33.772 50.950 -29.112 1.00 88.26  ? 277 LYS   A NZ  1 
ATOM   340  N N   . PHE   A 1 63  ? 30.698 43.448 -26.959 1.00 104.99 ? 278 PHE   A N   1 
ATOM   341  C CA  . PHE   A 1 63  ? 30.762 42.456 -25.907 1.00 108.52 ? 278 PHE   A CA  1 
ATOM   342  C C   . PHE   A 1 63  ? 30.015 41.221 -26.374 1.00 117.09 ? 278 PHE   A C   1 
ATOM   343  O O   . PHE   A 1 63  ? 29.172 41.311 -27.289 1.00 116.06 ? 278 PHE   A O   1 
ATOM   344  C CB  . PHE   A 1 63  ? 30.184 43.007 -24.588 1.00 103.99 ? 278 PHE   A CB  1 
ATOM   345  C CG  . PHE   A 1 63  ? 30.781 44.355 -24.155 1.00 94.86  ? 278 PHE   A CG  1 
ATOM   346  C CD1 . PHE   A 1 63  ? 30.317 45.547 -24.701 1.00 92.37  ? 278 PHE   A CD1 1 
ATOM   347  C CD2 . PHE   A 1 63  ? 31.747 44.425 -23.155 1.00 85.38  ? 278 PHE   A CD2 1 
ATOM   348  C CE1 . PHE   A 1 63  ? 30.847 46.773 -24.305 1.00 86.82  ? 278 PHE   A CE1 1 
ATOM   349  C CE2 . PHE   A 1 63  ? 32.270 45.642 -22.749 1.00 77.42  ? 278 PHE   A CE2 1 
ATOM   350  C CZ  . PHE   A 1 63  ? 31.821 46.820 -23.328 1.00 79.24  ? 278 PHE   A CZ  1 
ATOM   351  N N   . PRO   A 1 64  ? 30.285 40.050 -25.808 1.00 141.59 ? 279 PRO   A N   1 
ATOM   352  C CA  . PRO   A 1 64  ? 29.692 38.816 -26.326 1.00 143.31 ? 279 PRO   A CA  1 
ATOM   353  C C   . PRO   A 1 64  ? 28.203 38.750 -26.031 1.00 144.19 ? 279 PRO   A C   1 
ATOM   354  O O   . PRO   A 1 64  ? 27.752 39.100 -24.936 1.00 142.12 ? 279 PRO   A O   1 
ATOM   355  C CB  . PRO   A 1 64  ? 30.456 37.718 -25.582 1.00 144.96 ? 279 PRO   A CB  1 
ATOM   356  C CG  . PRO   A 1 64  ? 30.817 38.358 -24.273 1.00 140.96 ? 279 PRO   A CG  1 
ATOM   357  C CD  . PRO   A 1 64  ? 31.131 39.798 -24.617 1.00 139.83 ? 279 PRO   A CD  1 
ATOM   358  N N   . GLU   A 1 65  ? 27.435 38.294 -27.021 1.00 129.19 ? 280 GLU   A N   1 
ATOM   359  C CA  . GLU   A 1 65  ? 26.023 38.020 -26.775 1.00 126.75 ? 280 GLU   A CA  1 
ATOM   360  C C   . GLU   A 1 65  ? 25.892 36.686 -26.062 1.00 124.41 ? 280 GLU   A C   1 
ATOM   361  O O   . GLU   A 1 65  ? 24.886 35.986 -26.190 1.00 123.25 ? 280 GLU   A O   1 
ATOM   362  C CB  . GLU   A 1 65  ? 25.212 38.042 -28.074 1.00 125.89 ? 280 GLU   A CB  1 
ATOM   363  C CG  . GLU   A 1 65  ? 25.153 39.405 -28.749 1.00 125.22 ? 280 GLU   A CG  1 
ATOM   364  C CD  . GLU   A 1 65  ? 24.225 40.377 -28.018 1.00 122.83 ? 280 GLU   A CD  1 
ATOM   365  O OE1 . GLU   A 1 65  ? 23.922 41.457 -28.570 1.00 120.18 ? 280 GLU   A OE1 1 
ATOM   366  O OE2 . GLU   A 1 65  ? 23.807 40.059 -26.883 1.00 121.65 ? 280 GLU   A OE2 1 
ATOM   367  N N   . LYS   A 1 66  ? 26.914 36.341 -25.303 1.00 128.08 ? 281 LYS   A N   1 
ATOM   368  C CA  . LYS   A 1 66  ? 26.944 35.090 -24.574 1.00 121.40 ? 281 LYS   A CA  1 
ATOM   369  C C   . LYS   A 1 66  ? 26.743 35.353 -23.089 1.00 116.97 ? 281 LYS   A C   1 
ATOM   370  O O   . LYS   A 1 66  ? 26.767 36.494 -22.618 1.00 115.84 ? 281 LYS   A O   1 
ATOM   371  C CB  . LYS   A 1 66  ? 28.264 34.357 -24.817 1.00 112.38 ? 281 LYS   A CB  1 
ATOM   372  N N   . LYS   A 1 67  ? 26.519 34.263 -22.356 1.00 105.89 ? 282 LYS   A N   1 
ATOM   373  C CA  . LYS   A 1 67  ? 26.390 34.322 -20.912 1.00 105.20 ? 282 LYS   A CA  1 
ATOM   374  C C   . LYS   A 1 67  ? 27.483 35.201 -20.327 1.00 104.18 ? 282 LYS   A C   1 
ATOM   375  O O   . LYS   A 1 67  ? 28.662 35.060 -20.670 1.00 103.72 ? 282 LYS   A O   1 
ATOM   376  C CB  . LYS   A 1 67  ? 26.468 32.910 -20.326 1.00 107.08 ? 282 LYS   A CB  1 
ATOM   377  N N   . GLY   A 1 68  ? 27.077 36.113 -19.445 1.00 105.55 ? 283 GLY   A N   1 
ATOM   378  C CA  . GLY   A 1 68  ? 27.982 37.114 -18.928 1.00 98.57  ? 283 GLY   A CA  1 
ATOM   379  C C   . GLY   A 1 68  ? 28.331 38.206 -19.907 1.00 99.99  ? 283 GLY   A C   1 
ATOM   380  O O   . GLY   A 1 68  ? 29.368 38.848 -19.755 1.00 99.29  ? 283 GLY   A O   1 
ATOM   381  N N   . GLY   A 1 69  ? 27.513 38.422 -20.925 1.00 100.89 ? 284 GLY   A N   1 
ATOM   382  C CA  . GLY   A 1 69  ? 27.695 39.564 -21.793 1.00 102.14 ? 284 GLY   A CA  1 
ATOM   383  C C   . GLY   A 1 69  ? 26.891 40.753 -21.312 1.00 94.29  ? 284 GLY   A C   1 
ATOM   384  O O   . GLY   A 1 69  ? 26.038 40.632 -20.437 1.00 93.64  ? 284 GLY   A O   1 
ATOM   385  N N   . LEU   A 1 70  ? 27.177 41.912 -21.905 1.00 95.13  ? 285 LEU   A N   1 
ATOM   386  C CA  . LEU   A 1 70  ? 26.450 43.122 -21.550 1.00 92.69  ? 285 LEU   A CA  1 
ATOM   387  C C   . LEU   A 1 70  ? 24.946 42.923 -21.679 1.00 93.59  ? 285 LEU   A C   1 
ATOM   388  O O   . LEU   A 1 70  ? 24.190 43.180 -20.735 1.00 92.92  ? 285 LEU   A O   1 
ATOM   389  C CB  . LEU   A 1 70  ? 26.913 44.286 -22.421 1.00 92.06  ? 285 LEU   A CB  1 
ATOM   390  C CG  . LEU   A 1 70  ? 26.562 45.669 -21.876 1.00 89.56  ? 285 LEU   A CG  1 
ATOM   391  C CD1 . LEU   A 1 70  ? 26.792 45.722 -20.373 1.00 84.34  ? 285 LEU   A CD1 1 
ATOM   392  C CD2 . LEU   A 1 70  ? 27.371 46.727 -22.573 1.00 89.40  ? 285 LEU   A CD2 1 
ATOM   393  N N   . ARG   A 1 71  ? 24.493 42.470 -22.848 1.00 91.45  ? 286 ARG   A N   1 
ATOM   394  C CA  . ARG   A 1 71  ? 23.065 42.260 -23.072 1.00 94.21  ? 286 ARG   A CA  1 
ATOM   395  C C   . ARG   A 1 71  ? 22.451 41.414 -21.959 1.00 92.20  ? 286 ARG   A C   1 
ATOM   396  O O   . ARG   A 1 71  ? 21.478 41.818 -21.310 1.00 92.17  ? 286 ARG   A O   1 
ATOM   397  C CB  . ARG   A 1 71  ? 22.845 41.606 -24.440 1.00 97.20  ? 286 ARG   A CB  1 
ATOM   398  N N   . GLU   A 1 72  ? 23.017 40.226 -21.727 1.00 92.94  ? 287 GLU   A N   1 
ATOM   399  C CA  . GLU   A 1 72  ? 22.494 39.329 -20.702 1.00 92.50  ? 287 GLU   A CA  1 
ATOM   400  C C   . GLU   A 1 72  ? 22.416 40.023 -19.338 1.00 91.67  ? 287 GLU   A C   1 
ATOM   401  O O   . GLU   A 1 72  ? 21.352 40.065 -18.709 1.00 91.40  ? 287 GLU   A O   1 
ATOM   402  C CB  . GLU   A 1 72  ? 23.372 38.074 -20.631 1.00 95.18  ? 287 GLU   A CB  1 
ATOM   403  C CG  . GLU   A 1 72  ? 22.979 37.073 -19.565 1.00 97.42  ? 287 GLU   A CG  1 
ATOM   404  C CD  . GLU   A 1 72  ? 23.440 35.669 -19.896 1.00 101.55 ? 287 GLU   A CD  1 
ATOM   405  O OE1 . GLU   A 1 72  ? 22.896 35.048 -20.835 1.00 103.08 ? 287 GLU   A OE1 1 
ATOM   406  O OE2 . GLU   A 1 72  ? 24.367 35.190 -19.209 1.00 103.62 ? 287 GLU   A OE2 1 
ATOM   407  N N   . LEU   A 1 73  ? 23.538 40.578 -18.868 1.00 94.46  ? 288 LEU   A N   1 
ATOM   408  C CA  . LEU   A 1 73  ? 23.583 41.163 -17.527 1.00 95.37  ? 288 LEU   A CA  1 
ATOM   409  C C   . LEU   A 1 73  ? 22.597 42.313 -17.384 1.00 92.65  ? 288 LEU   A C   1 
ATOM   410  O O   . LEU   A 1 73  ? 21.824 42.367 -16.422 1.00 94.52  ? 288 LEU   A O   1 
ATOM   411  C CB  . LEU   A 1 73  ? 24.996 41.641 -17.210 1.00 92.50  ? 288 LEU   A CB  1 
ATOM   412  C CG  . LEU   A 1 73  ? 25.992 40.513 -16.988 1.00 93.38  ? 288 LEU   A CG  1 
ATOM   413  C CD1 . LEU   A 1 73  ? 27.387 41.042 -16.739 1.00 90.59  ? 288 LEU   A CD1 1 
ATOM   414  C CD2 . LEU   A 1 73  ? 25.529 39.668 -15.824 1.00 92.08  ? 288 LEU   A CD2 1 
ATOM   415  N N   . TYR   A 1 74  ? 22.631 43.263 -18.319 1.00 89.41  ? 289 TYR   A N   1 
ATOM   416  C CA  . TYR   A 1 74  ? 21.734 44.403 -18.210 1.00 86.67  ? 289 TYR   A CA  1 
ATOM   417  C C   . TYR   A 1 74  ? 20.291 43.957 -18.080 1.00 88.80  ? 289 TYR   A C   1 
ATOM   418  O O   . TYR   A 1 74  ? 19.497 44.619 -17.406 1.00 88.73  ? 289 TYR   A O   1 
ATOM   419  C CB  . TYR   A 1 74  ? 21.877 45.320 -19.417 1.00 85.85  ? 289 TYR   A CB  1 
ATOM   420  C CG  . TYR   A 1 74  ? 21.291 46.678 -19.164 1.00 83.73  ? 289 TYR   A CG  1 
ATOM   421  C CD1 . TYR   A 1 74  ? 22.041 47.668 -18.552 1.00 81.84  ? 289 TYR   A CD1 1 
ATOM   422  C CD2 . TYR   A 1 74  ? 19.982 46.960 -19.504 1.00 87.23  ? 289 TYR   A CD2 1 
ATOM   423  C CE1 . TYR   A 1 74  ? 21.512 48.907 -18.301 1.00 82.79  ? 289 TYR   A CE1 1 
ATOM   424  C CE2 . TYR   A 1 74  ? 19.442 48.194 -19.258 1.00 89.38  ? 289 TYR   A CE2 1 
ATOM   425  C CZ  . TYR   A 1 74  ? 20.210 49.165 -18.654 1.00 86.35  ? 289 TYR   A CZ  1 
ATOM   426  O OH  . TYR   A 1 74  ? 19.666 50.401 -18.402 1.00 86.77  ? 289 TYR   A OH  1 
ATOM   427  N N   . ASP   A 1 75  ? 19.935 42.835 -18.709 1.00 94.11  ? 290 ASP   A N   1 
ATOM   428  C CA  . ASP   A 1 75  ? 18.553 42.369 -18.668 1.00 95.35  ? 290 ASP   A CA  1 
ATOM   429  C C   . ASP   A 1 75  ? 18.117 42.018 -17.254 1.00 93.88  ? 290 ASP   A C   1 
ATOM   430  O O   . ASP   A 1 75  ? 16.980 42.306 -16.860 1.00 93.43  ? 290 ASP   A O   1 
ATOM   431  C CB  . ASP   A 1 75  ? 18.388 41.177 -19.600 1.00 97.83  ? 290 ASP   A CB  1 
ATOM   432  C CG  . ASP   A 1 75  ? 17.964 41.594 -20.982 1.00 100.11 ? 290 ASP   A CG  1 
ATOM   433  O OD1 . ASP   A 1 75  ? 18.852 41.974 -21.781 1.00 96.68  ? 290 ASP   A OD1 1 
ATOM   434  O OD2 . ASP   A 1 75  ? 16.746 41.595 -21.254 1.00 106.48 ? 290 ASP   A OD2 1 
ATOM   435  N N   . ARG   A 1 76  ? 18.989 41.373 -16.480 1.00 93.38  ? 291 ARG   A N   1 
ATOM   436  C CA  . ARG   A 1 76  ? 18.633 41.071 -15.101 1.00 91.19  ? 291 ARG   A CA  1 
ATOM   437  C C   . ARG   A 1 76  ? 18.477 42.355 -14.298 1.00 87.93  ? 291 ARG   A C   1 
ATOM   438  O O   . ARG   A 1 76  ? 17.443 42.577 -13.660 1.00 89.52  ? 291 ARG   A O   1 
ATOM   439  C CB  . ARG   A 1 76  ? 19.677 40.143 -14.479 1.00 93.23  ? 291 ARG   A CB  1 
ATOM   440  C CG  . ARG   A 1 76  ? 19.162 38.740 -14.205 1.00 99.20  ? 291 ARG   A CG  1 
ATOM   441  C CD  . ARG   A 1 76  ? 20.302 37.799 -13.863 1.00 103.67 ? 291 ARG   A CD  1 
ATOM   442  N NE  . ARG   A 1 76  ? 21.009 37.366 -15.064 1.00 108.19 ? 291 ARG   A NE  1 
ATOM   443  C CZ  . ARG   A 1 76  ? 22.241 36.870 -15.082 1.00 110.15 ? 291 ARG   A CZ  1 
ATOM   444  N NH1 . ARG   A 1 76  ? 22.941 36.706 -13.969 1.00 110.25 ? 291 ARG   A NH1 1 
ATOM   445  N NH2 . ARG   A 1 76  ? 22.787 36.527 -16.246 1.00 107.44 ? 291 ARG   A NH2 1 
ATOM   446  N N   . GLY   A 1 77  ? 19.477 43.222 -14.343 1.00 86.80  ? 292 GLY   A N   1 
ATOM   447  C CA  . GLY   A 1 77  ? 19.418 44.466 -13.625 1.00 83.37  ? 292 GLY   A CA  1 
ATOM   448  C C   . GLY   A 1 77  ? 20.166 44.361 -12.317 1.00 82.74  ? 292 GLY   A C   1 
ATOM   449  O O   . GLY   A 1 77  ? 20.770 43.329 -12.007 1.00 83.85  ? 292 GLY   A O   1 
ATOM   450  N N   . PRO   A 1 78  ? 20.104 45.418 -11.493 1.00 78.34  ? 293 PRO   A N   1 
ATOM   451  C CA  . PRO   A 1 78  ? 19.301 46.633 -11.679 1.00 75.99  ? 293 PRO   A CA  1 
ATOM   452  C C   . PRO   A 1 78  ? 19.972 47.600 -12.607 1.00 74.47  ? 293 PRO   A C   1 
ATOM   453  O O   . PRO   A 1 78  ? 21.185 47.810 -12.563 1.00 73.66  ? 293 PRO   A O   1 
ATOM   454  C CB  . PRO   A 1 78  ? 19.184 47.197 -10.257 1.00 76.55  ? 293 PRO   A CB  1 
ATOM   455  C CG  . PRO   A 1 78  ? 20.467 46.768 -9.600  1.00 76.25  ? 293 PRO   A CG  1 
ATOM   456  C CD  . PRO   A 1 78  ? 20.767 45.395 -10.175 1.00 76.65  ? 293 PRO   A CD  1 
ATOM   457  N N   . PRO   A 1 79  ? 19.159 48.226 -13.454 1.00 77.20  ? 294 PRO   A N   1 
ATOM   458  C CA  . PRO   A 1 79  ? 19.710 49.131 -14.474 1.00 77.91  ? 294 PRO   A CA  1 
ATOM   459  C C   . PRO   A 1 79  ? 20.673 50.160 -13.908 1.00 74.90  ? 294 PRO   A C   1 
ATOM   460  O O   . PRO   A 1 79  ? 21.680 50.465 -14.554 1.00 74.18  ? 294 PRO   A O   1 
ATOM   461  C CB  . PRO   A 1 79  ? 18.467 49.802 -15.075 1.00 79.13  ? 294 PRO   A CB  1 
ATOM   462  C CG  . PRO   A 1 79  ? 17.282 49.239 -14.397 1.00 78.54  ? 294 PRO   A CG  1 
ATOM   463  C CD  . PRO   A 1 79  ? 17.686 48.208 -13.396 1.00 79.23  ? 294 PRO   A CD  1 
ATOM   464  N N   . HIS   A 1 80  ? 20.405 50.697 -12.708 1.00 74.86  ? 295 HIS   A N   1 
ATOM   465  C CA  . HIS   A 1 80  ? 21.251 51.722 -12.096 1.00 71.92  ? 295 HIS   A CA  1 
ATOM   466  C C   . HIS   A 1 80  ? 22.638 51.219 -11.721 1.00 70.74  ? 295 HIS   A C   1 
ATOM   467  O O   . HIS   A 1 80  ? 23.453 52.039 -11.295 1.00 69.02  ? 295 HIS   A O   1 
ATOM   468  C CB  . HIS   A 1 80  ? 20.578 52.323 -10.843 1.00 72.50  ? 295 HIS   A CB  1 
ATOM   469  C CG  . HIS   A 1 80  ? 20.624 51.436 -9.633  1.00 73.67  ? 295 HIS   A CG  1 
ATOM   470  N ND1 . HIS   A 1 80  ? 19.585 50.601 -9.287  1.00 76.14  ? 295 HIS   A ND1 1 
ATOM   471  C CD2 . HIS   A 1 80  ? 21.597 51.228 -8.711  1.00 72.82  ? 295 HIS   A CD2 1 
ATOM   472  C CE1 . HIS   A 1 80  ? 19.910 49.922 -8.200  1.00 78.27  ? 295 HIS   A CE1 1 
ATOM   473  N NE2 . HIS   A 1 80  ? 21.127 50.282 -7.831  1.00 75.78  ? 295 HIS   A NE2 1 
ATOM   474  N N   . ALA   A 1 81  ? 22.938 49.930 -11.847 1.00 69.11  ? 296 ALA   A N   1 
ATOM   475  C CA  . ALA   A 1 81  ? 24.261 49.412 -11.531 1.00 70.48  ? 296 ALA   A CA  1 
ATOM   476  C C   . ALA   A 1 81  ? 25.265 49.517 -12.680 1.00 70.19  ? 296 ALA   A C   1 
ATOM   477  O O   . ALA   A 1 81  ? 26.441 49.192 -12.469 1.00 65.73  ? 296 ALA   A O   1 
ATOM   478  C CB  . ALA   A 1 81  ? 24.156 47.951 -11.103 1.00 68.28  ? 296 ALA   A CB  1 
ATOM   479  N N   . PHE   A 1 82  ? 24.850 49.956 -13.872 1.00 69.75  ? 297 PHE   A N   1 
ATOM   480  C CA  . PHE   A 1 82  ? 25.623 49.777 -15.104 1.00 70.84  ? 297 PHE   A CA  1 
ATOM   481  C C   . PHE   A 1 82  ? 26.229 51.096 -15.571 1.00 70.74  ? 297 PHE   A C   1 
ATOM   482  O O   . PHE   A 1 82  ? 25.538 52.121 -15.632 1.00 68.70  ? 297 PHE   A O   1 
ATOM   483  C CB  . PHE   A 1 82  ? 24.747 49.183 -16.209 1.00 71.95  ? 297 PHE   A CB  1 
ATOM   484  C CG  . PHE   A 1 82  ? 24.424 47.727 -16.008 1.00 73.80  ? 297 PHE   A CG  1 
ATOM   485  C CD1 . PHE   A 1 82  ? 23.532 47.334 -15.034 1.00 73.91  ? 297 PHE   A CD1 1 
ATOM   486  C CD2 . PHE   A 1 82  ? 25.031 46.749 -16.781 1.00 72.43  ? 297 PHE   A CD2 1 
ATOM   487  C CE1 . PHE   A 1 82  ? 23.244 45.993 -14.843 1.00 76.84  ? 297 PHE   A CE1 1 
ATOM   488  C CE2 . PHE   A 1 82  ? 24.743 45.417 -16.597 1.00 76.06  ? 297 PHE   A CE2 1 
ATOM   489  C CZ  . PHE   A 1 82  ? 23.851 45.037 -15.629 1.00 77.49  ? 297 PHE   A CZ  1 
ATOM   490  N N   . PHE   A 1 83  ? 27.512 51.055 -15.932 1.00 70.19  ? 298 PHE   A N   1 
ATOM   491  C CA  . PHE   A 1 83  ? 28.274 52.241 -16.268 1.00 68.30  ? 298 PHE   A CA  1 
ATOM   492  C C   . PHE   A 1 83  ? 29.194 51.950 -17.443 1.00 69.52  ? 298 PHE   A C   1 
ATOM   493  O O   . PHE   A 1 83  ? 29.668 50.828 -17.622 1.00 66.10  ? 298 PHE   A O   1 
ATOM   494  C CB  . PHE   A 1 83  ? 29.109 52.708 -15.086 1.00 68.13  ? 298 PHE   A CB  1 
ATOM   495  C CG  . PHE   A 1 83  ? 28.297 53.179 -13.918 1.00 70.57  ? 298 PHE   A CG  1 
ATOM   496  C CD1 . PHE   A 1 83  ? 27.865 52.293 -12.950 1.00 68.33  ? 298 PHE   A CD1 1 
ATOM   497  C CD2 . PHE   A 1 83  ? 27.956 54.510 -13.789 1.00 70.46  ? 298 PHE   A CD2 1 
ATOM   498  C CE1 . PHE   A 1 83  ? 27.115 52.726 -11.894 1.00 69.81  ? 298 PHE   A CE1 1 
ATOM   499  C CE2 . PHE   A 1 83  ? 27.203 54.951 -12.692 1.00 72.87  ? 298 PHE   A CE2 1 
ATOM   500  C CZ  . PHE   A 1 83  ? 26.782 54.063 -11.760 1.00 68.85  ? 298 PHE   A CZ  1 
ATOM   501  N N   . LEU   A 1 84  ? 29.446 52.977 -18.241 1.00 69.58  ? 299 LEU   A N   1 
ATOM   502  C CA  . LEU   A 1 84  ? 30.429 52.931 -19.309 1.00 65.68  ? 299 LEU   A CA  1 
ATOM   503  C C   . LEU   A 1 84  ? 31.556 53.871 -18.927 1.00 63.69  ? 299 LEU   A C   1 
ATOM   504  O O   . LEU   A 1 84  ? 31.302 54.978 -18.458 1.00 63.04  ? 299 LEU   A O   1 
ATOM   505  C CB  . LEU   A 1 84  ? 29.805 53.347 -20.641 1.00 69.48  ? 299 LEU   A CB  1 
ATOM   506  C CG  . LEU   A 1 84  ? 30.654 53.540 -21.899 1.00 67.85  ? 299 LEU   A CG  1 
ATOM   507  C CD1 . LEU   A 1 84  ? 31.169 52.207 -22.412 1.00 67.21  ? 299 LEU   A CD1 1 
ATOM   508  C CD2 . LEU   A 1 84  ? 29.812 54.203 -22.941 1.00 68.50  ? 299 LEU   A CD2 1 
ATOM   509  N N   . VAL   A 1 85  ? 32.794 53.424 -19.089 1.00 66.99  ? 300 VAL   A N   1 
ATOM   510  C CA  . VAL   A 1 85  ? 33.947 54.301 -18.962 1.00 66.14  ? 300 VAL   A CA  1 
ATOM   511  C C   . VAL   A 1 85  ? 34.663 54.300 -20.303 1.00 64.34  ? 300 VAL   A C   1 
ATOM   512  O O   . VAL   A 1 85  ? 35.093 53.246 -20.777 1.00 59.62  ? 300 VAL   A O   1 
ATOM   513  C CB  . VAL   A 1 85  ? 34.892 53.857 -17.838 1.00 63.23  ? 300 VAL   A CB  1 
ATOM   514  C CG1 . VAL   A 1 85  ? 36.149 54.708 -17.877 1.00 63.23  ? 300 VAL   A CG1 1 
ATOM   515  C CG2 . VAL   A 1 85  ? 34.193 53.959 -16.471 1.00 63.57  ? 300 VAL   A CG2 1 
ATOM   516  N N   . LYS   A 1 86  ? 34.771 55.462 -20.927 1.00 65.68  ? 301 LYS   A N   1 
ATOM   517  C CA  . LYS   A 1 86  ? 35.676 55.610 -22.062 1.00 64.57  ? 301 LYS   A CA  1 
ATOM   518  C C   . LYS   A 1 86  ? 37.016 56.122 -21.558 1.00 65.32  ? 301 LYS   A C   1 
ATOM   519  O O   . LYS   A 1 86  ? 37.066 57.105 -20.814 1.00 65.23  ? 301 LYS   A O   1 
ATOM   520  C CB  . LYS   A 1 86  ? 35.120 56.535 -23.144 1.00 65.45  ? 301 LYS   A CB  1 
ATOM   521  C CG  . LYS   A 1 86  ? 35.818 56.306 -24.535 1.00 66.92  ? 301 LYS   A CG  1 
ATOM   522  C CD  . LYS   A 1 86  ? 34.974 56.837 -25.703 1.00 72.84  ? 301 LYS   A CD  1 
ATOM   523  C CE  . LYS   A 1 86  ? 35.627 56.632 -27.097 1.00 73.56  ? 301 LYS   A CE  1 
ATOM   524  N NZ  . LYS   A 1 86  ? 34.814 55.668 -27.917 1.00 74.84  ? 301 LYS   A NZ  1 
ATOM   525  N N   . PHE   A 1 87  ? 38.087 55.428 -21.942 1.00 59.43  ? 302 PHE   A N   1 
ATOM   526  C CA  . PHE   A 1 87  ? 39.445 55.717 -21.507 1.00 62.12  ? 302 PHE   A CA  1 
ATOM   527  C C   . PHE   A 1 87  ? 40.261 56.253 -22.673 1.00 65.81  ? 302 PHE   A C   1 
ATOM   528  O O   . PHE   A 1 87  ? 40.211 55.712 -23.790 1.00 59.98  ? 302 PHE   A O   1 
ATOM   529  C CB  . PHE   A 1 87  ? 40.134 54.461 -20.963 1.00 61.68  ? 302 PHE   A CB  1 
ATOM   530  C CG  . PHE   A 1 87  ? 39.927 54.226 -19.502 1.00 61.80  ? 302 PHE   A CG  1 
ATOM   531  C CD1 . PHE   A 1 87  ? 40.042 55.263 -18.593 1.00 63.05  ? 302 PHE   A CD1 1 
ATOM   532  C CD2 . PHE   A 1 87  ? 39.645 52.965 -19.033 1.00 61.67  ? 302 PHE   A CD2 1 
ATOM   533  C CE1 . PHE   A 1 87  ? 39.860 55.052 -17.244 1.00 62.09  ? 302 PHE   A CE1 1 
ATOM   534  C CE2 . PHE   A 1 87  ? 39.461 52.744 -17.673 1.00 62.60  ? 302 PHE   A CE2 1 
ATOM   535  C CZ  . PHE   A 1 87  ? 39.562 53.792 -16.789 1.00 62.67  ? 302 PHE   A CZ  1 
ATOM   536  N N   . TRP   A 1 88  ? 41.024 57.307 -22.409 1.00 64.14  ? 303 TRP   A N   1 
ATOM   537  C CA  . TRP   A 1 88  ? 42.079 57.753 -23.308 1.00 67.96  ? 303 TRP   A CA  1 
ATOM   538  C C   . TRP   A 1 88  ? 43.389 57.468 -22.585 1.00 67.78  ? 303 TRP   A C   1 
ATOM   539  O O   . TRP   A 1 88  ? 43.803 58.229 -21.706 1.00 64.61  ? 303 TRP   A O   1 
ATOM   540  C CB  . TRP   A 1 88  ? 41.917 59.220 -23.696 1.00 65.39  ? 303 TRP   A CB  1 
ATOM   541  C CG  . TRP   A 1 88  ? 40.711 59.397 -24.559 1.00 66.91  ? 303 TRP   A CG  1 
ATOM   542  C CD1 . TRP   A 1 88  ? 40.673 59.370 -25.917 1.00 67.31  ? 303 TRP   A CD1 1 
ATOM   543  C CD2 . TRP   A 1 88  ? 39.357 59.615 -24.126 1.00 71.09  ? 303 TRP   A CD2 1 
ATOM   544  N NE1 . TRP   A 1 88  ? 39.385 59.561 -26.365 1.00 69.11  ? 303 TRP   A NE1 1 
ATOM   545  C CE2 . TRP   A 1 88  ? 38.558 59.713 -25.286 1.00 71.13  ? 303 TRP   A CE2 1 
ATOM   546  C CE3 . TRP   A 1 88  ? 38.746 59.755 -22.874 1.00 68.40  ? 303 TRP   A CE3 1 
ATOM   547  C CZ2 . TRP   A 1 88  ? 37.180 59.941 -25.231 1.00 75.77  ? 303 TRP   A CZ2 1 
ATOM   548  C CZ3 . TRP   A 1 88  ? 37.368 59.982 -22.822 1.00 69.32  ? 303 TRP   A CZ3 1 
ATOM   549  C CH2 . TRP   A 1 88  ? 36.606 60.071 -23.993 1.00 74.40  ? 303 TRP   A CH2 1 
ATOM   550  N N   . ALA   A 1 89  ? 44.027 56.356 -22.953 1.00 63.60  ? 304 ALA   A N   1 
ATOM   551  C CA  . ALA   A 1 89  ? 45.159 55.835 -22.210 1.00 65.82  ? 304 ALA   A CA  1 
ATOM   552  C C   . ALA   A 1 89  ? 46.468 56.430 -22.695 1.00 68.36  ? 304 ALA   A C   1 
ATOM   553  O O   . ALA   A 1 89  ? 46.662 56.690 -23.892 1.00 64.02  ? 304 ALA   A O   1 
ATOM   554  C CB  . ALA   A 1 89  ? 45.216 54.319 -22.311 1.00 63.72  ? 304 ALA   A CB  1 
ATOM   555  N N   . ASP   A 1 90  ? 47.362 56.639 -21.745 1.00 68.33  ? 305 ASP   A N   1 
ATOM   556  C CA  . ASP   A 1 90  ? 48.708 57.123 -21.992 1.00 69.64  ? 305 ASP   A CA  1 
ATOM   557  C C   . ASP   A 1 90  ? 49.595 55.896 -22.182 1.00 73.12  ? 305 ASP   A C   1 
ATOM   558  O O   . ASP   A 1 90  ? 49.802 55.130 -21.237 1.00 72.30  ? 305 ASP   A O   1 
ATOM   559  C CB  . ASP   A 1 90  ? 49.159 57.976 -20.805 1.00 69.96  ? 305 ASP   A CB  1 
ATOM   560  C CG  . ASP   A 1 90  ? 50.468 58.672 -21.045 1.00 75.30  ? 305 ASP   A CG  1 
ATOM   561  O OD1 . ASP   A 1 90  ? 51.210 58.253 -21.966 1.00 79.34  ? 305 ASP   A OD1 1 
ATOM   562  O OD2 . ASP   A 1 90  ? 50.775 59.622 -20.296 1.00 76.31  ? 305 ASP   A OD2 1 
ATOM   563  N N   . LEU   A 1 91  ? 50.098 55.679 -23.399 1.00 72.85  ? 306 LEU   A N   1 
ATOM   564  C CA  . LEU   A 1 91  ? 50.984 54.546 -23.659 1.00 77.33  ? 306 LEU   A CA  1 
ATOM   565  C C   . LEU   A 1 91  ? 52.425 54.983 -23.860 1.00 82.06  ? 306 LEU   A C   1 
ATOM   566  O O   . LEU   A 1 91  ? 53.236 54.225 -24.403 1.00 83.03  ? 306 LEU   A O   1 
ATOM   567  C CB  . LEU   A 1 91  ? 50.505 53.730 -24.860 1.00 73.46  ? 306 LEU   A CB  1 
ATOM   568  C CG  . LEU   A 1 91  ? 49.045 53.314 -24.720 1.00 71.03  ? 306 LEU   A CG  1 
ATOM   569  C CD1 . LEU   A 1 91  ? 48.649 52.391 -25.828 1.00 68.75  ? 306 LEU   A CD1 1 
ATOM   570  C CD2 . LEU   A 1 91  ? 48.830 52.626 -23.369 1.00 71.11  ? 306 LEU   A CD2 1 
ATOM   571  N N   . ASN   A 1 92  ? 52.764 56.180 -23.408 1.00 85.26  ? 307 ASN   A N   1 
ATOM   572  C CA  . ASN   A 1 92  ? 54.075 56.777 -23.633 1.00 88.12  ? 307 ASN   A CA  1 
ATOM   573  C C   . ASN   A 1 92  ? 54.922 56.515 -22.390 1.00 91.34  ? 307 ASN   A C   1 
ATOM   574  O O   . ASN   A 1 92  ? 54.787 57.209 -21.379 1.00 88.95  ? 307 ASN   A O   1 
ATOM   575  C CB  . ASN   A 1 92  ? 53.910 58.267 -23.921 1.00 91.07  ? 307 ASN   A CB  1 
ATOM   576  C CG  . ASN   A 1 92  ? 55.202 58.942 -24.300 1.00 95.92  ? 307 ASN   A CG  1 
ATOM   577  O OD1 . ASN   A 1 92  ? 55.570 59.956 -23.696 1.00 97.97  ? 307 ASN   A OD1 1 
ATOM   578  N ND2 . ASN   A 1 92  ? 55.888 58.413 -25.316 1.00 92.76  ? 307 ASN   A ND2 1 
ATOM   579  N N   . TRP   A 1 93  ? 55.795 55.510 -22.462 1.00 86.24  ? 308 TRP   A N   1 
ATOM   580  C CA  . TRP   A 1 93  ? 56.658 55.174 -21.326 1.00 84.31  ? 308 TRP   A CA  1 
ATOM   581  C C   . TRP   A 1 93  ? 57.860 54.365 -21.799 1.00 82.83  ? 308 TRP   A C   1 
ATOM   582  O O   . TRP   A 1 93  ? 58.973 54.884 -21.888 1.00 84.80  ? 308 TRP   A O   1 
ATOM   583  C CB  . TRP   A 1 93  ? 55.864 54.409 -20.240 1.00 82.33  ? 308 TRP   A CB  1 
ATOM   584  C CG  . TRP   A 1 93  ? 55.792 52.909 -20.457 1.00 81.82  ? 308 TRP   A CG  1 
ATOM   585  C CD1 . TRP   A 1 93  ? 56.617 51.953 -19.910 1.00 83.60  ? 308 TRP   A CD1 1 
ATOM   586  C CD2 . TRP   A 1 93  ? 54.861 52.198 -21.300 1.00 80.82  ? 308 TRP   A CD2 1 
ATOM   587  N NE1 . TRP   A 1 93  ? 56.252 50.700 -20.360 1.00 82.57  ? 308 TRP   A NE1 1 
ATOM   588  C CE2 . TRP   A 1 93  ? 55.180 50.821 -21.210 1.00 81.43  ? 308 TRP   A CE2 1 
ATOM   589  C CE3 . TRP   A 1 93  ? 53.797 52.592 -22.126 1.00 79.34  ? 308 TRP   A CE3 1 
ATOM   590  C CZ2 . TRP   A 1 93  ? 54.469 49.836 -21.920 1.00 79.53  ? 308 TRP   A CZ2 1 
ATOM   591  C CZ3 . TRP   A 1 93  ? 53.088 51.614 -22.821 1.00 77.23  ? 308 TRP   A CZ3 1 
ATOM   592  C CH2 . TRP   A 1 93  ? 53.426 50.253 -22.710 1.00 77.88  ? 308 TRP   A CH2 1 
ATOM   593  N N   . SER   A 1 107 ? 62.376 50.275 -22.644 1.00 111.80 ? 322 SER   A N   1 
ATOM   594  C CA  . SER   A 1 107 ? 61.186 49.618 -23.177 1.00 111.57 ? 322 SER   A CA  1 
ATOM   595  C C   . SER   A 1 107 ? 60.620 48.551 -22.211 1.00 114.60 ? 322 SER   A C   1 
ATOM   596  O O   . SER   A 1 107 ? 59.630 48.796 -21.518 1.00 109.79 ? 322 SER   A O   1 
ATOM   597  C CB  . SER   A 1 107 ? 61.502 48.999 -24.546 1.00 109.83 ? 322 SER   A CB  1 
ATOM   598  O OG  . SER   A 1 107 ? 61.172 49.894 -25.595 1.00 104.94 ? 322 SER   A OG  1 
ATOM   599  N N   . SER   A 1 108 ? 61.264 47.382 -22.167 1.00 120.70 ? 323 SER   A N   1 
ATOM   600  C CA  . SER   A 1 108 ? 60.759 46.233 -21.422 1.00 121.44 ? 323 SER   A CA  1 
ATOM   601  C C   . SER   A 1 108 ? 61.167 46.310 -19.955 1.00 119.89 ? 323 SER   A C   1 
ATOM   602  O O   . SER   A 1 108 ? 62.341 46.530 -19.640 1.00 121.42 ? 323 SER   A O   1 
ATOM   603  C CB  . SER   A 1 108 ? 61.288 44.936 -22.040 1.00 120.25 ? 323 SER   A CB  1 
ATOM   604  O OG  . SER   A 1 108 ? 60.238 44.171 -22.606 1.00 118.02 ? 323 SER   A OG  1 
ATOM   605  N N   . GLY   A 1 109 ? 60.200 46.093 -19.062 1.00 117.99 ? 324 GLY   A N   1 
ATOM   606  C CA  . GLY   A 1 109 ? 60.425 46.220 -17.635 1.00 119.48 ? 324 GLY   A CA  1 
ATOM   607  C C   . GLY   A 1 109 ? 60.210 44.936 -16.862 1.00 119.62 ? 324 GLY   A C   1 
ATOM   608  O O   . GLY   A 1 109 ? 60.668 43.872 -17.289 1.00 121.57 ? 324 GLY   A O   1 
ATOM   609  N N   . GLY   A 1 110 ? 59.503 45.006 -15.737 1.00 110.26 ? 325 GLY   A N   1 
ATOM   610  C CA  . GLY   A 1 110 ? 58.803 46.152 -15.180 1.00 105.50 ? 325 GLY   A CA  1 
ATOM   611  C C   . GLY   A 1 110 ? 57.454 45.689 -14.672 1.00 98.01  ? 325 GLY   A C   1 
ATOM   612  O O   . GLY   A 1 110 ? 56.833 44.848 -15.309 1.00 96.46  ? 325 GLY   A O   1 
ATOM   613  N N   . PHE   A 1 111 ? 56.978 46.208 -13.545 1.00 93.61  ? 326 PHE   A N   1 
ATOM   614  C CA  . PHE   A 1 111 ? 55.777 45.656 -12.919 1.00 87.73  ? 326 PHE   A CA  1 
ATOM   615  C C   . PHE   A 1 111 ? 54.538 46.299 -13.532 1.00 84.65  ? 326 PHE   A C   1 
ATOM   616  O O   . PHE   A 1 111 ? 54.324 47.509 -13.391 1.00 85.06  ? 326 PHE   A O   1 
ATOM   617  C CB  . PHE   A 1 111 ? 55.772 45.865 -11.406 1.00 90.14  ? 326 PHE   A CB  1 
ATOM   618  C CG  . PHE   A 1 111 ? 54.586 45.227 -10.720 1.00 86.77  ? 326 PHE   A CG  1 
ATOM   619  C CD1 . PHE   A 1 111 ? 54.562 43.866 -10.461 1.00 87.29  ? 326 PHE   A CD1 1 
ATOM   620  C CD2 . PHE   A 1 111 ? 53.473 45.980 -10.399 1.00 85.14  ? 326 PHE   A CD2 1 
ATOM   621  C CE1 . PHE   A 1 111 ? 53.461 43.276 -9.866  1.00 85.04  ? 326 PHE   A CE1 1 
ATOM   622  C CE2 . PHE   A 1 111 ? 52.368 45.401 -9.806  1.00 83.45  ? 326 PHE   A CE2 1 
ATOM   623  C CZ  . PHE   A 1 111 ? 52.358 44.048 -9.528  1.00 82.43  ? 326 PHE   A CZ  1 
ATOM   624  N N   . TYR   A 1 112 ? 53.719 45.491 -14.203 1.00 83.65  ? 327 TYR   A N   1 
ATOM   625  C CA  . TYR   A 1 112 ? 52.428 45.923 -14.722 1.00 81.30  ? 327 TYR   A CA  1 
ATOM   626  C C   . TYR   A 1 112 ? 51.346 45.505 -13.741 1.00 79.29  ? 327 TYR   A C   1 
ATOM   627  O O   . TYR   A 1 112 ? 51.283 44.342 -13.332 1.00 79.56  ? 327 TYR   A O   1 
ATOM   628  C CB  . TYR   A 1 112 ? 52.174 45.329 -16.110 1.00 80.30  ? 327 TYR   A CB  1 
ATOM   629  C CG  . TYR   A 1 112 ? 53.211 45.767 -17.121 1.00 82.13  ? 327 TYR   A CG  1 
ATOM   630  C CD1 . TYR   A 1 112 ? 54.487 45.243 -17.083 1.00 84.60  ? 327 TYR   A CD1 1 
ATOM   631  C CD2 . TYR   A 1 112 ? 52.930 46.744 -18.060 1.00 78.71  ? 327 TYR   A CD2 1 
ATOM   632  C CE1 . TYR   A 1 112 ? 55.438 45.648 -17.962 1.00 88.00  ? 327 TYR   A CE1 1 
ATOM   633  C CE2 . TYR   A 1 112 ? 53.889 47.155 -18.976 1.00 79.21  ? 327 TYR   A CE2 1 
ATOM   634  C CZ  . TYR   A 1 112 ? 55.137 46.604 -18.913 1.00 83.99  ? 327 TYR   A CZ  1 
ATOM   635  O OH  . TYR   A 1 112 ? 56.117 46.995 -19.782 1.00 87.60  ? 327 TYR   A OH  1 
ATOM   636  N N   . GLY   A 1 113 ? 50.505 46.449 -13.347 1.00 77.10  ? 328 GLY   A N   1 
ATOM   637  C CA  . GLY   A 1 113 ? 49.584 46.143 -12.277 1.00 75.64  ? 328 GLY   A CA  1 
ATOM   638  C C   . GLY   A 1 113 ? 48.290 46.903 -12.412 1.00 73.80  ? 328 GLY   A C   1 
ATOM   639  O O   . GLY   A 1 113 ? 48.171 47.847 -13.197 1.00 72.73  ? 328 GLY   A O   1 
ATOM   640  N N   . VAL   A 1 114 ? 47.314 46.463 -11.624 1.00 71.08  ? 329 VAL   A N   1 
ATOM   641  C CA  . VAL   A 1 114 ? 45.983 47.046 -11.595 1.00 72.18  ? 329 VAL   A CA  1 
ATOM   642  C C   . VAL   A 1 114 ? 45.613 47.237 -10.131 1.00 73.57  ? 329 VAL   A C   1 
ATOM   643  O O   . VAL   A 1 114 ? 45.833 46.335 -9.315  1.00 72.02  ? 329 VAL   A O   1 
ATOM   644  C CB  . VAL   A 1 114 ? 44.955 46.138 -12.294 1.00 71.14  ? 329 VAL   A CB  1 
ATOM   645  C CG1 . VAL   A 1 114 ? 43.556 46.634 -12.054 1.00 70.83  ? 329 VAL   A CG1 1 
ATOM   646  C CG2 . VAL   A 1 114 ? 45.252 45.996 -13.783 1.00 73.27  ? 329 VAL   A CG2 1 
ATOM   647  N N   . SER   A 1 115 ? 45.057 48.401 -9.795  1.00 72.50  ? 330 SER   A N   1 
ATOM   648  C CA  . SER   A 1 115 ? 44.629 48.701 -8.436  1.00 72.07  ? 330 SER   A CA  1 
ATOM   649  C C   . SER   A 1 115 ? 43.180 49.161 -8.471  1.00 70.41  ? 330 SER   A C   1 
ATOM   650  O O   . SER   A 1 115 ? 42.826 50.033 -9.268  1.00 69.66  ? 330 SER   A O   1 
ATOM   651  C CB  . SER   A 1 115 ? 45.512 49.779 -7.787  1.00 72.04  ? 330 SER   A CB  1 
ATOM   652  O OG  . SER   A 1 115 ? 46.749 49.239 -7.346  1.00 72.29  ? 330 SER   A OG  1 
ATOM   653  N N   . SER   A 1 116 ? 42.341 48.568 -7.622  1.00 69.70  ? 331 SER   A N   1 
ATOM   654  C CA  . SER   A 1 116 ? 40.996 49.082 -7.403  1.00 69.47  ? 331 SER   A CA  1 
ATOM   655  C C   . SER   A 1 116 ? 40.697 49.245 -5.922  1.00 69.57  ? 331 SER   A C   1 
ATOM   656  O O   . SER   A 1 116 ? 41.247 48.560 -5.060  1.00 69.97  ? 331 SER   A O   1 
ATOM   657  C CB  . SER   A 1 116 ? 39.947 48.214 -8.097  1.00 68.77  ? 331 SER   A CB  1 
ATOM   658  O OG  . SER   A 1 116 ? 40.507 46.974 -8.507  1.00 72.80  ? 331 SER   A OG  1 
ATOM   659  N N   . GLN   A 1 117 ? 39.853 50.217 -5.640  1.00 68.59  ? 332 GLN   A N   1 
ATOM   660  C CA  . GLN   A 1 117 ? 39.431 50.459 -4.280  1.00 69.76  ? 332 GLN   A CA  1 
ATOM   661  C C   . GLN   A 1 117 ? 37.974 50.871 -4.342  1.00 69.99  ? 332 GLN   A C   1 
ATOM   662  O O   . GLN   A 1 117 ? 37.641 51.857 -5.001  1.00 70.04  ? 332 GLN   A O   1 
ATOM   663  C CB  . GLN   A 1 117 ? 40.303 51.524 -3.611  1.00 70.12  ? 332 GLN   A CB  1 
ATOM   664  C CG  . GLN   A 1 117 ? 40.394 51.327 -2.080  1.00 74.65  ? 332 GLN   A CG  1 
ATOM   665  C CD  . GLN   A 1 117 ? 41.148 52.461 -1.399  1.00 78.08  ? 332 GLN   A CD  1 
ATOM   666  O OE1 . GLN   A 1 117 ? 42.378 52.561 -1.496  1.00 79.01  ? 332 GLN   A OE1 1 
ATOM   667  N NE2 . GLN   A 1 117 ? 40.409 53.336 -0.726  1.00 76.59  ? 332 GLN   A NE2 1 
ATOM   668  N N   . TYR   A 1 118 ? 37.117 50.090 -3.697  1.00 69.12  ? 333 TYR   A N   1 
ATOM   669  C CA  . TYR   A 1 118 ? 35.705 50.401 -3.567  1.00 70.37  ? 333 TYR   A CA  1 
ATOM   670  C C   . TYR   A 1 118 ? 35.391 50.628 -2.093  1.00 70.29  ? 333 TYR   A C   1 
ATOM   671  O O   . TYR   A 1 118 ? 36.185 50.304 -1.199  1.00 69.46  ? 333 TYR   A O   1 
ATOM   672  C CB  . TYR   A 1 118 ? 34.823 49.267 -4.117  1.00 69.14  ? 333 TYR   A CB  1 
ATOM   673  C CG  . TYR   A 1 118 ? 35.161 48.724 -5.487  1.00 67.71  ? 333 TYR   A CG  1 
ATOM   674  C CD1 . TYR   A 1 118 ? 36.159 47.774 -5.655  1.00 68.49  ? 333 TYR   A CD1 1 
ATOM   675  C CD2 . TYR   A 1 118 ? 34.436 49.114 -6.609  1.00 68.51  ? 333 TYR   A CD2 1 
ATOM   676  C CE1 . TYR   A 1 118 ? 36.451 47.240 -6.922  1.00 69.17  ? 333 TYR   A CE1 1 
ATOM   677  C CE2 . TYR   A 1 118 ? 34.721 48.595 -7.877  1.00 67.13  ? 333 TYR   A CE2 1 
ATOM   678  C CZ  . TYR   A 1 118 ? 35.726 47.670 -8.030  1.00 68.54  ? 333 TYR   A CZ  1 
ATOM   679  O OH  . TYR   A 1 118 ? 35.984 47.180 -9.302  1.00 70.79  ? 333 TYR   A OH  1 
ATOM   680  N N   . GLU   A 1 119 ? 34.206 51.175 -1.840  1.00 68.37  ? 334 GLU   A N   1 
ATOM   681  C CA  . GLU   A 1 119 ? 33.763 51.404 -0.476  1.00 70.59  ? 334 GLU   A CA  1 
ATOM   682  C C   . GLU   A 1 119 ? 32.250 51.286 -0.423  1.00 69.88  ? 334 GLU   A C   1 
ATOM   683  O O   . GLU   A 1 119 ? 31.567 51.474 -1.433  1.00 70.80  ? 334 GLU   A O   1 
ATOM   684  C CB  . GLU   A 1 119 ? 34.231 52.762 0.029   1.00 71.34  ? 334 GLU   A CB  1 
ATOM   685  C CG  . GLU   A 1 119 ? 33.512 53.914 -0.620  1.00 72.40  ? 334 GLU   A CG  1 
ATOM   686  C CD  . GLU   A 1 119 ? 34.165 55.225 -0.278  1.00 78.60  ? 334 GLU   A CD  1 
ATOM   687  O OE1 . GLU   A 1 119 ? 35.157 55.169 0.478   1.00 80.34  ? 334 GLU   A OE1 1 
ATOM   688  O OE2 . GLU   A 1 119 ? 33.715 56.293 -0.763  1.00 79.28  ? 334 GLU   A OE2 1 
ATOM   689  N N   . SER   A 1 120 ? 31.745 50.919 0.753   1.00 71.32  ? 335 SER   A N   1 
ATOM   690  C CA  . SER   A 1 120 ? 30.320 50.808 1.018   1.00 71.34  ? 335 SER   A CA  1 
ATOM   691  C C   . SER   A 1 120 ? 30.082 51.175 2.467   1.00 70.07  ? 335 SER   A C   1 
ATOM   692  O O   . SER   A 1 120 ? 31.017 51.318 3.255   1.00 71.16  ? 335 SER   A O   1 
ATOM   693  C CB  . SER   A 1 120 ? 29.799 49.398 0.776   1.00 71.27  ? 335 SER   A CB  1 
ATOM   694  O OG  . SER   A 1 120 ? 30.393 48.479 1.696   1.00 71.15  ? 335 SER   A OG  1 
ATOM   695  N N   . LEU   A 1 121 ? 28.807 51.313 2.816   1.00 68.76  ? 336 LEU   A N   1 
ATOM   696  C CA  . LEU   A 1 121 ? 28.418 51.374 4.214   1.00 69.59  ? 336 LEU   A CA  1 
ATOM   697  C C   . LEU   A 1 121 ? 28.015 50.023 4.771   1.00 69.12  ? 336 LEU   A C   1 
ATOM   698  O O   . LEU   A 1 121 ? 27.946 49.878 5.993   1.00 67.76  ? 336 LEU   A O   1 
ATOM   699  C CB  . LEU   A 1 121 ? 27.278 52.375 4.393   1.00 68.23  ? 336 LEU   A CB  1 
ATOM   700  C CG  . LEU   A 1 121 ? 27.735 53.815 4.120   1.00 68.90  ? 336 LEU   A CG  1 
ATOM   701  C CD1 . LEU   A 1 121 ? 26.566 54.665 3.690   1.00 69.96  ? 336 LEU   A CD1 1 
ATOM   702  C CD2 . LEU   A 1 121 ? 28.330 54.391 5.401   1.00 70.38  ? 336 LEU   A CD2 1 
ATOM   703  N N   . GLU   A 1 122 ? 27.755 49.038 3.916   1.00 66.78  ? 337 GLU   A N   1 
ATOM   704  C CA  . GLU   A 1 122 ? 27.407 47.703 4.373   1.00 67.11  ? 337 GLU   A CA  1 
ATOM   705  C C   . GLU   A 1 122 ? 28.662 46.843 4.395   1.00 68.75  ? 337 GLU   A C   1 
ATOM   706  O O   . GLU   A 1 122 ? 29.623 47.110 3.678   1.00 69.40  ? 337 GLU   A O   1 
ATOM   707  C CB  . GLU   A 1 122 ? 26.345 47.068 3.468   1.00 67.86  ? 337 GLU   A CB  1 
ATOM   708  C CG  . GLU   A 1 122 ? 24.994 47.827 3.448   1.00 70.68  ? 337 GLU   A CG  1 
ATOM   709  C CD  . GLU   A 1 122 ? 24.809 48.746 2.217   1.00 78.77  ? 337 GLU   A CD  1 
ATOM   710  O OE1 . GLU   A 1 122 ? 23.649 48.930 1.765   1.00 79.23  ? 337 GLU   A OE1 1 
ATOM   711  O OE2 . GLU   A 1 122 ? 25.820 49.258 1.662   1.00 76.15  ? 337 GLU   A OE2 1 
ATOM   712  N N   . HIS   A 1 123 ? 28.664 45.810 5.234   1.00 68.68  ? 338 HIS   A N   1 
ATOM   713  C CA  . HIS   A 1 123 ? 29.785 44.873 5.289   1.00 70.99  ? 338 HIS   A CA  1 
ATOM   714  C C   . HIS   A 1 123 ? 29.481 43.697 4.369   1.00 69.26  ? 338 HIS   A C   1 
ATOM   715  O O   . HIS   A 1 123 ? 28.585 42.895 4.662   1.00 68.86  ? 338 HIS   A O   1 
ATOM   716  C CB  . HIS   A 1 123 ? 30.035 44.367 6.706   1.00 69.77  ? 338 HIS   A CB  1 
ATOM   717  C CG  . HIS   A 1 123 ? 31.203 43.439 6.791   1.00 70.11  ? 338 HIS   A CG  1 
ATOM   718  N ND1 . HIS   A 1 123 ? 31.157 42.141 6.328   1.00 69.50  ? 338 HIS   A ND1 1 
ATOM   719  C CD2 . HIS   A 1 123 ? 32.456 43.624 7.271   1.00 71.64  ? 338 HIS   A CD2 1 
ATOM   720  C CE1 . HIS   A 1 123 ? 32.328 41.564 6.526   1.00 73.09  ? 338 HIS   A CE1 1 
ATOM   721  N NE2 . HIS   A 1 123 ? 33.133 42.441 7.099   1.00 72.87  ? 338 HIS   A NE2 1 
ATOM   722  N N   . MET   A 1 124 ? 30.255 43.564 3.287   1.00 70.63  ? 339 MET   A N   1 
ATOM   723  C CA  . MET   A 1 124 ? 30.078 42.503 2.299   1.00 71.20  ? 339 MET   A CA  1 
ATOM   724  C C   . MET   A 1 124 ? 31.425 41.840 2.010   1.00 69.82  ? 339 MET   A C   1 
ATOM   725  O O   . MET   A 1 124 ? 32.483 42.327 2.420   1.00 70.02  ? 339 MET   A O   1 
ATOM   726  C CB  . MET   A 1 124 ? 29.512 43.082 1.001   1.00 70.94  ? 339 MET   A CB  1 
ATOM   727  C CG  . MET   A 1 124 ? 28.396 44.063 1.232   1.00 70.87  ? 339 MET   A CG  1 
ATOM   728  S SD  . MET   A 1 124 ? 27.569 44.543 -0.267  1.00 69.09  ? 339 MET   A SD  1 
ATOM   729  C CE  . MET   A 1 124 ? 28.241 46.160 -0.592  1.00 68.44  ? 339 MET   A CE  1 
ATOM   730  N N   . THR   A 1 125 ? 31.407 40.731 1.278   1.00 70.58  ? 340 THR   A N   1 
ATOM   731  C CA  . THR   A 1 125 ? 32.581 40.313 0.520   1.00 74.23  ? 340 THR   A CA  1 
ATOM   732  C C   . THR   A 1 125 ? 32.244 40.420 -0.968  1.00 73.11  ? 340 THR   A C   1 
ATOM   733  O O   . THR   A 1 125 ? 31.119 40.102 -1.389  1.00 72.39  ? 340 THR   A O   1 
ATOM   734  C CB  . THR   A 1 125 ? 33.020 38.886 0.824   1.00 76.18  ? 340 THR   A CB  1 
ATOM   735  O OG1 . THR   A 1 125 ? 32.152 37.962 0.156   1.00 78.85  ? 340 THR   A OG1 1 
ATOM   736  C CG2 . THR   A 1 125 ? 32.946 38.621 2.291   1.00 77.18  ? 340 THR   A CG2 1 
ATOM   737  N N   . LEU   A 1 126 ? 33.210 40.881 -1.761  1.00 73.31  ? 341 LEU   A N   1 
ATOM   738  C CA  . LEU   A 1 126 ? 33.001 41.141 -3.181  1.00 72.80  ? 341 LEU   A CA  1 
ATOM   739  C C   . LEU   A 1 126 ? 33.618 40.045 -4.034  1.00 72.02  ? 341 LEU   A C   1 
ATOM   740  O O   . LEU   A 1 126 ? 34.665 39.474 -3.707  1.00 72.04  ? 341 LEU   A O   1 
ATOM   741  C CB  . LEU   A 1 126 ? 33.595 42.487 -3.592  1.00 70.46  ? 341 LEU   A CB  1 
ATOM   742  C CG  . LEU   A 1 126 ? 33.103 43.745 -2.876  1.00 69.12  ? 341 LEU   A CG  1 
ATOM   743  C CD1 . LEU   A 1 126 ? 33.895 44.952 -3.328  1.00 69.82  ? 341 LEU   A CD1 1 
ATOM   744  C CD2 . LEU   A 1 126 ? 31.598 43.963 -3.084  1.00 68.73  ? 341 LEU   A CD2 1 
ATOM   745  N N   . THR   A 1 127 ? 32.928 39.737 -5.125  1.00 71.94  ? 342 THR   A N   1 
ATOM   746  C CA  . THR   A 1 127 ? 33.445 38.883 -6.183  1.00 70.52  ? 342 THR   A CA  1 
ATOM   747  C C   . THR   A 1 127 ? 33.552 39.809 -7.379  1.00 67.76  ? 342 THR   A C   1 
ATOM   748  O O   . THR   A 1 127 ? 32.539 40.366 -7.817  1.00 68.39  ? 342 THR   A O   1 
ATOM   749  C CB  . THR   A 1 127 ? 32.520 37.708 -6.463  1.00 69.50  ? 342 THR   A CB  1 
ATOM   750  O OG1 . THR   A 1 127 ? 32.488 36.874 -5.307  1.00 72.54  ? 342 THR   A OG1 1 
ATOM   751  C CG2 . THR   A 1 127 ? 33.040 36.873 -7.635  1.00 68.19  ? 342 THR   A CG2 1 
ATOM   752  N N   . CYS   A 1 128 ? 34.779 40.067 -7.839  1.00 65.59  ? 343 CYS   A N   1 
ATOM   753  C CA  . CYS   A 1 128 ? 35.018 40.958 -8.978  1.00 67.04  ? 343 CYS   A CA  1 
ATOM   754  C C   . CYS   A 1 128 ? 35.416 40.101 -10.173 1.00 65.21  ? 343 CYS   A C   1 
ATOM   755  O O   . CYS   A 1 128 ? 36.367 39.314 -10.095 1.00 65.28  ? 343 CYS   A O   1 
ATOM   756  C CB  . CYS   A 1 128 ? 36.088 42.014 -8.668  1.00 65.93  ? 343 CYS   A CB  1 
ATOM   757  S SG  . CYS   A 1 128 ? 35.847 42.963 -7.056  1.00 73.60  ? 343 CYS   A SG  1 
ATOM   758  N N   . SER   A 1 129 ? 34.677 40.219 -11.260 1.00 64.69  ? 344 SER   A N   1 
ATOM   759  C CA  . SER   A 1 129 ? 35.002 39.488 -12.478 1.00 65.50  ? 344 SER   A CA  1 
ATOM   760  C C   . SER   A 1 129 ? 35.421 40.474 -13.559 1.00 65.06  ? 344 SER   A C   1 
ATOM   761  O O   . SER   A 1 129 ? 34.728 41.470 -13.801 1.00 64.50  ? 344 SER   A O   1 
ATOM   762  C CB  . SER   A 1 129 ? 33.814 38.636 -12.933 1.00 65.84  ? 344 SER   A CB  1 
ATOM   763  O OG  . SER   A 1 129 ? 33.781 38.523 -14.360 1.00 70.45  ? 344 SER   A OG  1 
ATOM   764  N N   . SER   A 1 130 ? 36.576 40.224 -14.178 1.00 66.13  ? 345 SER   A N   1 
ATOM   765  C CA  . SER   A 1 130 ? 37.092 41.042 -15.265 1.00 66.39  ? 345 SER   A CA  1 
ATOM   766  C C   . SER   A 1 130 ? 37.070 40.186 -16.519 1.00 68.27  ? 345 SER   A C   1 
ATOM   767  O O   . SER   A 1 130 ? 37.694 39.125 -16.553 1.00 68.12  ? 345 SER   A O   1 
ATOM   768  C CB  . SER   A 1 130 ? 38.512 41.534 -14.989 1.00 66.99  ? 345 SER   A CB  1 
ATOM   769  O OG  . SER   A 1 130 ? 38.563 42.371 -13.859 1.00 68.68  ? 345 SER   A OG  1 
ATOM   770  N N   . LYS   A 1 131 ? 36.355 40.637 -17.535 1.00 67.11  ? 346 LYS   A N   1 
ATOM   771  C CA  . LYS   A 1 131 ? 36.286 39.945 -18.805 1.00 69.30  ? 346 LYS   A CA  1 
ATOM   772  C C   . LYS   A 1 131 ? 36.913 40.845 -19.853 1.00 69.95  ? 346 LYS   A C   1 
ATOM   773  O O   . LYS   A 1 131 ? 36.394 41.928 -20.125 1.00 69.51  ? 346 LYS   A O   1 
ATOM   774  C CB  . LYS   A 1 131 ? 34.840 39.602 -19.168 1.00 69.97  ? 346 LYS   A CB  1 
ATOM   775  C CG  . LYS   A 1 131 ? 34.164 38.660 -18.195 1.00 72.87  ? 346 LYS   A CG  1 
ATOM   776  C CD  . LYS   A 1 131 ? 32.708 38.368 -18.566 1.00 77.22  ? 346 LYS   A CD  1 
ATOM   777  C CE  . LYS   A 1 131 ? 31.969 37.816 -17.325 1.00 81.60  ? 346 LYS   A CE  1 
ATOM   778  N NZ  . LYS   A 1 131 ? 30.467 37.897 -17.370 1.00 87.30  ? 346 LYS   A NZ  1 
ATOM   779  N N   . VAL   A 1 132 ? 38.034 40.415 -20.408 1.00 68.55  ? 347 VAL   A N   1 
ATOM   780  C CA  . VAL   A 1 132 ? 38.645 41.109 -21.532 1.00 70.32  ? 347 VAL   A CA  1 
ATOM   781  C C   . VAL   A 1 132 ? 38.107 40.516 -22.826 1.00 73.29  ? 347 VAL   A C   1 
ATOM   782  O O   . VAL   A 1 132 ? 38.127 39.292 -23.022 1.00 71.50  ? 347 VAL   A O   1 
ATOM   783  C CB  . VAL   A 1 132 ? 40.174 40.999 -21.490 1.00 70.17  ? 347 VAL   A CB  1 
ATOM   784  C CG1 . VAL   A 1 132 ? 40.760 41.717 -22.709 1.00 71.39  ? 347 VAL   A CG1 1 
ATOM   785  C CG2 . VAL   A 1 132 ? 40.707 41.579 -20.218 1.00 68.37  ? 347 VAL   A CG2 1 
ATOM   786  N N   . CYS   A 1 133 ? 37.653 41.387 -23.720 1.00 72.76  ? 348 CYS   A N   1 
ATOM   787  C CA  . CYS   A 1 133 ? 37.061 40.996 -24.985 1.00 76.08  ? 348 CYS   A CA  1 
ATOM   788  C C   . CYS   A 1 133 ? 37.847 41.593 -26.140 1.00 76.38  ? 348 CYS   A C   1 
ATOM   789  O O   . CYS   A 1 133 ? 38.203 42.772 -26.131 1.00 70.84  ? 348 CYS   A O   1 
ATOM   790  C CB  . CYS   A 1 133 ? 35.599 41.425 -25.083 1.00 79.53  ? 348 CYS   A CB  1 
ATOM   791  S SG  . CYS   A 1 133 ? 34.503 40.417 -24.121 1.00 83.73  ? 348 CYS   A SG  1 
ATOM   792  N N   . SER   A 1 134 ? 38.105 40.759 -27.134 1.00 78.58  ? 349 SER   A N   1 
ATOM   793  C CA  . SER   A 1 134 ? 38.796 41.161 -28.343 1.00 78.90  ? 349 SER   A CA  1 
ATOM   794  C C   . SER   A 1 134 ? 37.930 40.679 -29.493 1.00 80.09  ? 349 SER   A C   1 
ATOM   795  O O   . SER   A 1 134 ? 37.673 39.482 -29.608 1.00 80.86  ? 349 SER   A O   1 
ATOM   796  C CB  . SER   A 1 134 ? 40.206 40.565 -28.386 1.00 78.39  ? 349 SER   A CB  1 
ATOM   797  O OG  . SER   A 1 134 ? 40.823 40.828 -29.628 1.00 78.41  ? 349 SER   A OG  1 
ATOM   798  N N   . PHE   A 1 135 ? 37.440 41.606 -30.308 1.00 78.95  ? 350 PHE   A N   1 
ATOM   799  C CA  . PHE   A 1 135 ? 36.411 41.320 -31.303 1.00 79.03  ? 350 PHE   A CA  1 
ATOM   800  C C   . PHE   A 1 135 ? 35.244 40.532 -30.694 1.00 84.13  ? 350 PHE   A C   1 
ATOM   801  O O   . PHE   A 1 135 ? 35.034 39.356 -30.970 1.00 84.40  ? 350 PHE   A O   1 
ATOM   802  C CB  . PHE   A 1 135 ? 37.008 40.572 -32.491 1.00 76.43  ? 350 PHE   A CB  1 
ATOM   803  C CG  . PHE   A 1 135 ? 38.269 41.182 -33.031 1.00 75.37  ? 350 PHE   A CG  1 
ATOM   804  C CD1 . PHE   A 1 135 ? 39.511 40.893 -32.470 1.00 74.74  ? 350 PHE   A CD1 1 
ATOM   805  C CD2 . PHE   A 1 135 ? 38.200 42.081 -34.100 1.00 72.88  ? 350 PHE   A CD2 1 
ATOM   806  C CE1 . PHE   A 1 135 ? 40.677 41.475 -32.977 1.00 72.30  ? 350 PHE   A CE1 1 
ATOM   807  C CE2 . PHE   A 1 135 ? 39.353 42.659 -34.634 1.00 72.10  ? 350 PHE   A CE2 1 
ATOM   808  C CZ  . PHE   A 1 135 ? 40.597 42.363 -34.067 1.00 73.02  ? 350 PHE   A CZ  1 
ATOM   809  N N   . GLY   A 1 136 ? 34.498 41.215 -29.833 1.00 93.48  ? 351 GLY   A N   1 
ATOM   810  C CA  . GLY   A 1 136 ? 33.317 40.628 -29.225 1.00 96.77  ? 351 GLY   A CA  1 
ATOM   811  C C   . GLY   A 1 136 ? 33.548 39.382 -28.385 1.00 101.11 ? 351 GLY   A C   1 
ATOM   812  O O   . GLY   A 1 136 ? 32.788 39.130 -27.440 1.00 104.22 ? 351 GLY   A O   1 
ATOM   813  N N   . LYS   A 1 137 ? 34.578 38.590 -28.715 1.00 87.52  ? 352 LYS   A N   1 
ATOM   814  C CA  . LYS   A 1 137 ? 34.856 37.341 -28.008 1.00 85.09  ? 352 LYS   A CA  1 
ATOM   815  C C   . LYS   A 1 137 ? 35.704 37.575 -26.761 1.00 80.78  ? 352 LYS   A C   1 
ATOM   816  O O   . LYS   A 1 137 ? 36.652 38.365 -26.771 1.00 77.98  ? 352 LYS   A O   1 
ATOM   817  C CB  . LYS   A 1 137 ? 35.555 36.343 -28.932 1.00 83.95  ? 352 LYS   A CB  1 
ATOM   818  C CG  . LYS   A 1 137 ? 36.770 36.897 -29.673 1.00 82.54  ? 352 LYS   A CG  1 
ATOM   819  C CD  . LYS   A 1 137 ? 37.783 35.774 -29.974 1.00 82.76  ? 352 LYS   A CD  1 
ATOM   820  C CE  . LYS   A 1 137 ? 39.179 36.342 -30.227 1.00 80.76  ? 352 LYS   A CE  1 
ATOM   821  N NZ  . LYS   A 1 137 ? 39.185 37.559 -31.114 1.00 78.37  ? 352 LYS   A NZ  1 
ATOM   822  N N   . GLN   A 1 138 ? 35.351 36.867 -25.689 1.00 82.47  ? 353 GLN   A N   1 
ATOM   823  C CA  . GLN   A 1 138 ? 36.052 36.942 -24.407 1.00 77.73  ? 353 GLN   A CA  1 
ATOM   824  C C   . GLN   A 1 138 ? 37.373 36.193 -24.528 1.00 75.34  ? 353 GLN   A C   1 
ATOM   825  O O   . GLN   A 1 138 ? 37.369 34.974 -24.674 1.00 74.79  ? 353 GLN   A O   1 
ATOM   826  C CB  . GLN   A 1 138 ? 35.186 36.323 -23.309 1.00 75.79  ? 353 GLN   A CB  1 
ATOM   827  C CG  . GLN   A 1 138 ? 35.710 36.506 -21.878 1.00 73.65  ? 353 GLN   A CG  1 
ATOM   828  C CD  . GLN   A 1 138 ? 35.037 35.572 -20.856 1.00 75.04  ? 353 GLN   A CD  1 
ATOM   829  O OE1 . GLN   A 1 138 ? 34.006 35.904 -20.261 1.00 76.01  ? 353 GLN   A OE1 1 
ATOM   830  N NE2 . GLN   A 1 138 ? 35.625 34.383 -20.661 1.00 72.81  ? 353 GLN   A NE2 1 
ATOM   831  N N   . VAL   A 1 139 ? 38.508 36.897 -24.459 1.00 74.98  ? 354 VAL   A N   1 
ATOM   832  C CA  . VAL   A 1 139 ? 39.807 36.220 -24.461 1.00 76.30  ? 354 VAL   A CA  1 
ATOM   833  C C   . VAL   A 1 139 ? 40.361 35.978 -23.053 1.00 74.78  ? 354 VAL   A C   1 
ATOM   834  O O   . VAL   A 1 139 ? 41.236 35.117 -22.887 1.00 70.35  ? 354 VAL   A O   1 
ATOM   835  C CB  . VAL   A 1 139 ? 40.845 36.982 -25.322 1.00 76.08  ? 354 VAL   A CB  1 
ATOM   836  C CG1 . VAL   A 1 139 ? 40.481 36.910 -26.781 1.00 77.35  ? 354 VAL   A CG1 1 
ATOM   837  C CG2 . VAL   A 1 139 ? 40.952 38.433 -24.914 1.00 74.45  ? 354 VAL   A CG2 1 
ATOM   838  N N   . VAL   A 1 140 ? 39.894 36.707 -22.045 1.00 73.76  ? 355 VAL   A N   1 
ATOM   839  C CA  . VAL   A 1 140 ? 40.406 36.564 -20.683 1.00 71.71  ? 355 VAL   A CA  1 
ATOM   840  C C   . VAL   A 1 140 ? 39.271 36.787 -19.699 1.00 71.25  ? 355 VAL   A C   1 
ATOM   841  O O   . VAL   A 1 140 ? 38.515 37.750 -19.836 1.00 69.54  ? 355 VAL   A O   1 
ATOM   842  C CB  . VAL   A 1 140 ? 41.545 37.557 -20.370 1.00 71.19  ? 355 VAL   A CB  1 
ATOM   843  C CG1 . VAL   A 1 140 ? 42.132 37.256 -18.997 1.00 72.28  ? 355 VAL   A CG1 1 
ATOM   844  C CG2 . VAL   A 1 140 ? 42.630 37.467 -21.445 1.00 74.91  ? 355 VAL   A CG2 1 
ATOM   845  N N   . GLU   A 1 141 ? 39.162 35.918 -18.698 1.00 70.59  ? 356 GLU   A N   1 
ATOM   846  C CA  . GLU   A 1 141 ? 38.351 36.218 -17.528 1.00 70.27  ? 356 GLU   A CA  1 
ATOM   847  C C   . GLU   A 1 141 ? 39.191 36.048 -16.279 1.00 70.22  ? 356 GLU   A C   1 
ATOM   848  O O   . GLU   A 1 141 ? 39.881 35.040 -16.132 1.00 68.65  ? 356 GLU   A O   1 
ATOM   849  C CB  . GLU   A 1 141 ? 37.107 35.344 -17.396 1.00 70.36  ? 356 GLU   A CB  1 
ATOM   850  C CG  . GLU   A 1 141 ? 36.286 35.939 -16.249 1.00 72.64  ? 356 GLU   A CG  1 
ATOM   851  C CD  . GLU   A 1 141 ? 35.012 35.198 -15.929 1.00 73.94  ? 356 GLU   A CD  1 
ATOM   852  O OE1 . GLU   A 1 141 ? 34.904 34.011 -16.302 1.00 75.40  ? 356 GLU   A OE1 1 
ATOM   853  O OE2 . GLU   A 1 141 ? 34.143 35.802 -15.258 1.00 73.88  ? 356 GLU   A OE2 1 
ATOM   854  N N   . LYS   A 1 142 ? 39.099 37.023 -15.378 1.00 68.54  ? 357 LYS   A N   1 
ATOM   855  C CA  . LYS   A 1 142 ? 39.782 36.974 -14.091 1.00 71.13  ? 357 LYS   A CA  1 
ATOM   856  C C   . LYS   A 1 142 ? 38.801 37.240 -12.948 1.00 71.40  ? 357 LYS   A C   1 
ATOM   857  O O   . LYS   A 1 142 ? 38.187 38.305 -12.878 1.00 67.87  ? 357 LYS   A O   1 
ATOM   858  C CB  . LYS   A 1 142 ? 40.927 37.988 -14.051 1.00 70.10  ? 357 LYS   A CB  1 
ATOM   859  C CG  . LYS   A 1 142 ? 42.125 37.540 -13.229 1.00 74.17  ? 357 LYS   A CG  1 
ATOM   860  C CD  . LYS   A 1 142 ? 43.348 38.393 -13.526 1.00 76.86  ? 357 LYS   A CD  1 
ATOM   861  C CE  . LYS   A 1 142 ? 44.509 38.028 -12.616 1.00 78.07  ? 357 LYS   A CE  1 
ATOM   862  N NZ  . LYS   A 1 142 ? 45.825 38.279 -13.267 1.00 79.18  ? 357 LYS   A NZ  1 
ATOM   863  N N   . VAL   A 1 143 ? 38.661 36.262 -12.060 1.00 68.74  ? 358 VAL   A N   1 
ATOM   864  C CA  . VAL   A 1 143 ? 37.743 36.346 -10.926 1.00 72.17  ? 358 VAL   A CA  1 
ATOM   865  C C   . VAL   A 1 143 ? 38.557 36.523 -9.654  1.00 71.85  ? 358 VAL   A C   1 
ATOM   866  O O   . VAL   A 1 143 ? 39.449 35.713 -9.368  1.00 69.53  ? 358 VAL   A O   1 
ATOM   867  C CB  . VAL   A 1 143 ? 36.841 35.105 -10.797 1.00 70.70  ? 358 VAL   A CB  1 
ATOM   868  C CG1 . VAL   A 1 143 ? 35.832 35.330 -9.644  1.00 69.72  ? 358 VAL   A CG1 1 
ATOM   869  C CG2 . VAL   A 1 143 ? 36.125 34.852 -12.086 1.00 72.06  ? 358 VAL   A CG2 1 
ATOM   870  N N   . GLU   A 1 144 ? 38.226 37.541 -8.875  1.00 68.69  ? 359 GLU   A N   1 
ATOM   871  C CA  . GLU   A 1 144 ? 38.910 37.799 -7.628  1.00 71.12  ? 359 GLU   A CA  1 
ATOM   872  C C   . GLU   A 1 144 ? 37.905 38.017 -6.519  1.00 71.64  ? 359 GLU   A C   1 
ATOM   873  O O   . GLU   A 1 144 ? 36.795 38.414 -6.776  1.00 69.94  ? 359 GLU   A O   1 
ATOM   874  C CB  . GLU   A 1 144 ? 39.815 39.004 -7.762  1.00 70.36  ? 359 GLU   A CB  1 
ATOM   875  C CG  . GLU   A 1 144 ? 41.236 38.673 -8.147  1.00 74.27  ? 359 GLU   A CG  1 
ATOM   876  C CD  . GLU   A 1 144 ? 41.831 39.672 -9.108  1.00 79.99  ? 359 GLU   A CD  1 
ATOM   877  O OE1 . GLU   A 1 144 ? 41.079 40.437 -9.723  1.00 78.83  ? 359 GLU   A OE1 1 
ATOM   878  O OE2 . GLU   A 1 144 ? 43.060 39.690 -9.261  1.00 83.50  ? 359 GLU   A OE2 1 
ATOM   879  N N   . THR   A 1 145 ? 38.297 37.725 -5.288  1.00 71.00  ? 360 THR   A N   1 
ATOM   880  C CA  . THR   A 1 145 ? 37.450 37.955 -4.122  1.00 74.46  ? 360 THR   A CA  1 
ATOM   881  C C   . THR   A 1 145 ? 38.128 38.892 -3.113  1.00 73.81  ? 360 THR   A C   1 
ATOM   882  O O   . THR   A 1 145 ? 39.328 38.762 -2.835  1.00 74.43  ? 360 THR   A O   1 
ATOM   883  C CB  . THR   A 1 145 ? 37.091 36.620 -3.471  1.00 73.54  ? 360 THR   A CB  1 
ATOM   884  O OG1 . THR   A 1 145 ? 36.352 35.824 -4.413  1.00 70.40  ? 360 THR   A OG1 1 
ATOM   885  C CG2 . THR   A 1 145 ? 36.222 36.869 -2.284  1.00 74.39  ? 360 THR   A CG2 1 
ATOM   886  N N   . GLU   A 1 146 ? 37.364 39.832 -2.540  1.00 72.92  ? 361 GLU   A N   1 
ATOM   887  C CA  . GLU   A 1 146 ? 37.940 40.792 -1.597  1.00 73.37  ? 361 GLU   A CA  1 
ATOM   888  C C   . GLU   A 1 146 ? 36.974 41.036 -0.441  1.00 72.79  ? 361 GLU   A C   1 
ATOM   889  O O   . GLU   A 1 146 ? 35.799 41.349 -0.663  1.00 71.62  ? 361 GLU   A O   1 
ATOM   890  C CB  . GLU   A 1 146 ? 38.294 42.125 -2.295  1.00 72.29  ? 361 GLU   A CB  1 
ATOM   891  C CG  . GLU   A 1 146 ? 38.805 43.219 -1.352  1.00 73.60  ? 361 GLU   A CG  1 
ATOM   892  C CD  . GLU   A 1 146 ? 40.071 42.834 -0.581  1.00 75.80  ? 361 GLU   A CD  1 
ATOM   893  O OE1 . GLU   A 1 146 ? 40.529 41.666 -0.714  1.00 79.88  ? 361 GLU   A OE1 1 
ATOM   894  O OE2 . GLU   A 1 146 ? 40.500 43.647 0.284   1.00 77.45  ? 361 GLU   A OE2 1 
ATOM   895  N N   . ARG   A 1 147 ? 37.476 40.916 0.787   1.00 77.69  ? 362 ARG   A N   1 
ATOM   896  C CA  . ARG   A 1 147 ? 36.645 41.062 1.984   1.00 77.72  ? 362 ARG   A CA  1 
ATOM   897  C C   . ARG   A 1 147 ? 36.615 42.511 2.463   1.00 78.01  ? 362 ARG   A C   1 
ATOM   898  O O   . ARG   A 1 147 ? 37.581 43.261 2.295   1.00 80.35  ? 362 ARG   A O   1 
ATOM   899  C CB  . ARG   A 1 147 ? 37.153 40.176 3.119   1.00 76.90  ? 362 ARG   A CB  1 
ATOM   900  C CG  . ARG   A 1 147 ? 36.160 40.045 4.278   1.00 84.32  ? 362 ARG   A CG  1 
ATOM   901  C CD  . ARG   A 1 147 ? 36.496 38.840 5.154   1.00 86.47  ? 362 ARG   A CD  1 
ATOM   902  N NE  . ARG   A 1 147 ? 35.429 38.546 6.098   1.00 89.56  ? 362 ARG   A NE  1 
ATOM   903  C CZ  . ARG   A 1 147 ? 34.325 37.880 5.787   1.00 92.91  ? 362 ARG   A CZ  1 
ATOM   904  N NH1 . ARG   A 1 147 ? 34.114 37.422 4.558   1.00 92.47  ? 362 ARG   A NH1 1 
ATOM   905  N NH2 . ARG   A 1 147 ? 33.411 37.662 6.729   1.00 92.86  ? 362 ARG   A NH2 1 
ATOM   906  N N   . ALA   A 1 148 ? 35.497 42.907 3.067   1.00 79.43  ? 363 ALA   A N   1 
ATOM   907  C CA  . ALA   A 1 148 ? 35.421 44.265 3.587   1.00 79.22  ? 363 ALA   A CA  1 
ATOM   908  C C   . ALA   A 1 148 ? 36.492 44.471 4.644   1.00 78.36  ? 363 ALA   A C   1 
ATOM   909  O O   . ALA   A 1 148 ? 36.857 43.550 5.379   1.00 79.82  ? 363 ALA   A O   1 
ATOM   910  C CB  . ALA   A 1 148 ? 34.038 44.557 4.166   1.00 76.53  ? 363 ALA   A CB  1 
ATOM   911  N N   . GLN   A 1 149 ? 37.025 45.681 4.685   1.00 75.40  ? 364 GLN   A N   1 
ATOM   912  C CA  . GLN   A 1 149 ? 37.928 46.127 5.734   1.00 76.33  ? 364 GLN   A CA  1 
ATOM   913  C C   . GLN   A 1 149 ? 37.333 47.389 6.330   1.00 79.30  ? 364 GLN   A C   1 
ATOM   914  O O   . GLN   A 1 149 ? 36.919 48.288 5.592   1.00 75.36  ? 364 GLN   A O   1 
ATOM   915  C CB  . GLN   A 1 149 ? 39.334 46.400 5.194   1.00 77.57  ? 364 GLN   A CB  1 
ATOM   916  C CG  . GLN   A 1 149 ? 40.281 47.091 6.175   1.00 79.91  ? 364 GLN   A CG  1 
ATOM   917  C CD  . GLN   A 1 149 ? 40.726 46.171 7.307   1.00 83.84  ? 364 GLN   A CD  1 
ATOM   918  O OE1 . GLN   A 1 149 ? 40.904 46.599 8.455   1.00 83.35  ? 364 GLN   A OE1 1 
ATOM   919  N NE2 . GLN   A 1 149 ? 40.903 44.893 6.983   1.00 82.09  ? 364 GLN   A NE2 1 
ATOM   920  N N   . LEU   A 1 150 ? 37.264 47.448 7.654   1.00 78.63  ? 365 LEU   A N   1 
ATOM   921  C CA  . LEU   A 1 150 ? 36.674 48.596 8.322   1.00 80.24  ? 365 LEU   A CA  1 
ATOM   922  C C   . LEU   A 1 150 ? 37.728 49.677 8.478   1.00 81.17  ? 365 LEU   A C   1 
ATOM   923  O O   . LEU   A 1 150 ? 38.830 49.408 8.960   1.00 84.56  ? 365 LEU   A O   1 
ATOM   924  C CB  . LEU   A 1 150 ? 36.084 48.191 9.671   1.00 79.82  ? 365 LEU   A CB  1 
ATOM   925  C CG  . LEU   A 1 150 ? 35.581 49.339 10.552  1.00 82.14  ? 365 LEU   A CG  1 
ATOM   926  C CD1 . LEU   A 1 150 ? 34.130 49.675 10.260  1.00 77.90  ? 365 LEU   A CD1 1 
ATOM   927  C CD2 . LEU   A 1 150 ? 35.760 49.024 12.052  1.00 82.43  ? 365 LEU   A CD2 1 
ATOM   928  N N   . GLU   A 1 151 ? 37.404 50.885 8.021   1.00 78.02  ? 366 GLU   A N   1 
ATOM   929  C CA  . GLU   A 1 151 ? 38.364 51.987 8.015   1.00 80.77  ? 366 GLU   A CA  1 
ATOM   930  C C   . GLU   A 1 151 ? 37.575 53.286 7.957   1.00 82.90  ? 366 GLU   A C   1 
ATOM   931  O O   . GLU   A 1 151 ? 36.929 53.565 6.941   1.00 83.67  ? 366 GLU   A O   1 
ATOM   932  C CB  . GLU   A 1 151 ? 39.306 51.884 6.819   1.00 81.06  ? 366 GLU   A CB  1 
ATOM   933  C CG  . GLU   A 1 151 ? 40.228 53.098 6.588   1.00 85.50  ? 366 GLU   A CG  1 
ATOM   934  C CD  . GLU   A 1 151 ? 41.029 53.006 5.283   1.00 87.68  ? 366 GLU   A CD  1 
ATOM   935  O OE1 . GLU   A 1 151 ? 41.966 52.173 5.174   1.00 85.70  ? 366 GLU   A OE1 1 
ATOM   936  O OE2 . GLU   A 1 151 ? 40.720 53.801 4.356   1.00 89.09  ? 366 GLU   A OE2 1 
ATOM   937  N N   . ASP   A 1 152 ? 37.618 54.077 9.032   1.00 84.79  ? 367 ASP   A N   1 
ATOM   938  C CA  . ASP   A 1 152 ? 37.174 55.474 8.974   1.00 86.19  ? 367 ASP   A CA  1 
ATOM   939  C C   . ASP   A 1 152 ? 35.644 55.573 8.956   1.00 84.55  ? 367 ASP   A C   1 
ATOM   940  O O   . ASP   A 1 152 ? 35.072 56.369 8.213   1.00 87.28  ? 367 ASP   A O   1 
ATOM   941  C CB  . ASP   A 1 152 ? 37.781 56.168 7.747   1.00 91.77  ? 367 ASP   A CB  1 
ATOM   942  C CG  . ASP   A 1 152 ? 38.998 57.029 8.076   1.00 97.81  ? 367 ASP   A CG  1 
ATOM   943  O OD1 . ASP   A 1 152 ? 39.753 56.699 9.019   1.00 102.67 ? 367 ASP   A OD1 1 
ATOM   944  O OD2 . ASP   A 1 152 ? 39.195 58.056 7.395   1.00 101.40 ? 367 ASP   A OD2 1 
ATOM   945  N N   . GLY   A 1 153 ? 34.977 54.740 9.747   1.00 83.84  ? 368 GLY   A N   1 
ATOM   946  C CA  . GLY   A 1 153 ? 33.525 54.638 9.660   1.00 82.23  ? 368 GLY   A CA  1 
ATOM   947  C C   . GLY   A 1 153 ? 32.959 54.214 8.313   1.00 80.59  ? 368 GLY   A C   1 
ATOM   948  O O   . GLY   A 1 153 ? 31.945 54.771 7.868   1.00 80.05  ? 368 GLY   A O   1 
ATOM   949  N N   . ARG   A 1 154 ? 33.580 53.241 7.650   1.00 77.67  ? 369 ARG   A N   1 
ATOM   950  C CA  . ARG   A 1 154 ? 33.064 52.694 6.398   1.00 77.85  ? 369 ARG   A CA  1 
ATOM   951  C C   . ARG   A 1 154 ? 33.880 51.461 6.035   1.00 76.93  ? 369 ARG   A C   1 
ATOM   952  O O   . ARG   A 1 154 ? 34.959 51.225 6.585   1.00 77.66  ? 369 ARG   A O   1 
ATOM   953  C CB  . ARG   A 1 154 ? 33.126 53.721 5.270   1.00 78.16  ? 369 ARG   A CB  1 
ATOM   954  C CG  . ARG   A 1 154 ? 34.489 54.344 5.185   1.00 80.89  ? 369 ARG   A CG  1 
ATOM   955  C CD  . ARG   A 1 154 ? 34.524 55.587 4.350   1.00 84.70  ? 369 ARG   A CD  1 
ATOM   956  N NE  . ARG   A 1 154 ? 35.647 55.536 3.418   1.00 86.64  ? 369 ARG   A NE  1 
ATOM   957  C CZ  . ARG   A 1 154 ? 35.967 56.497 2.560   1.00 88.82  ? 369 ARG   A CZ  1 
ATOM   958  N NH1 . ARG   A 1 154 ? 35.346 57.677 2.567   1.00 90.00  ? 369 ARG   A NH1 1 
ATOM   959  N NH2 . ARG   A 1 154 ? 36.925 56.265 1.661   1.00 89.47  ? 369 ARG   A NH2 1 
ATOM   960  N N   . PHE   A 1 155 ? 33.358 50.684 5.096   1.00 73.31  ? 370 PHE   A N   1 
ATOM   961  C CA  . PHE   A 1 155 ? 34.042 49.489 4.629   1.00 77.22  ? 370 PHE   A CA  1 
ATOM   962  C C   . PHE   A 1 155 ? 34.756 49.795 3.324   1.00 74.45  ? 370 PHE   A C   1 
ATOM   963  O O   . PHE   A 1 155 ? 34.174 50.401 2.415   1.00 72.96  ? 370 PHE   A O   1 
ATOM   964  C CB  . PHE   A 1 155 ? 33.048 48.342 4.481   1.00 75.85  ? 370 PHE   A CB  1 
ATOM   965  C CG  . PHE   A 1 155 ? 32.411 47.978 5.782   1.00 72.72  ? 370 PHE   A CG  1 
ATOM   966  C CD1 . PHE   A 1 155 ? 33.126 47.282 6.739   1.00 73.59  ? 370 PHE   A CD1 1 
ATOM   967  C CD2 . PHE   A 1 155 ? 31.128 48.403 6.088   1.00 73.13  ? 370 PHE   A CD2 1 
ATOM   968  C CE1 . PHE   A 1 155 ? 32.557 46.983 7.973   1.00 75.13  ? 370 PHE   A CE1 1 
ATOM   969  C CE2 . PHE   A 1 155 ? 30.550 48.100 7.328   1.00 72.02  ? 370 PHE   A CE2 1 
ATOM   970  C CZ  . PHE   A 1 155 ? 31.268 47.387 8.255   1.00 71.38  ? 370 PHE   A CZ  1 
ATOM   971  N N   . VAL   A 1 156 ? 36.034 49.437 3.257   1.00 74.07  ? 371 VAL   A N   1 
ATOM   972  C CA  . VAL   A 1 156 ? 36.850 49.665 2.071   1.00 75.65  ? 371 VAL   A CA  1 
ATOM   973  C C   . VAL   A 1 156 ? 37.255 48.308 1.508   1.00 75.37  ? 371 VAL   A C   1 
ATOM   974  O O   . VAL   A 1 156 ? 37.513 47.369 2.269   1.00 75.23  ? 371 VAL   A O   1 
ATOM   975  C CB  . VAL   A 1 156 ? 38.083 50.536 2.395   1.00 76.66  ? 371 VAL   A CB  1 
ATOM   976  C CG1 . VAL   A 1 156 ? 37.659 51.771 3.226   1.00 79.55  ? 371 VAL   A CG1 1 
ATOM   977  C CG2 . VAL   A 1 156 ? 39.132 49.727 3.125   1.00 76.86  ? 371 VAL   A CG2 1 
ATOM   978  N N   . TYR   A 1 157 ? 37.262 48.191 0.176   1.00 74.07  ? 372 TYR   A N   1 
ATOM   979  C CA  . TYR   A 1 157 ? 37.597 46.948 -0.525  1.00 74.50  ? 372 TYR   A CA  1 
ATOM   980  C C   . TYR   A 1 157 ? 38.791 47.230 -1.426  1.00 76.55  ? 372 TYR   A C   1 
ATOM   981  O O   . TYR   A 1 157 ? 38.648 47.881 -2.470  1.00 73.21  ? 372 TYR   A O   1 
ATOM   982  C CB  . TYR   A 1 157 ? 36.405 46.414 -1.328  1.00 73.49  ? 372 TYR   A CB  1 
ATOM   983  C CG  . TYR   A 1 157 ? 35.137 46.300 -0.504  1.00 72.82  ? 372 TYR   A CG  1 
ATOM   984  C CD1 . TYR   A 1 157 ? 34.350 47.408 -0.255  1.00 72.77  ? 372 TYR   A CD1 1 
ATOM   985  C CD2 . TYR   A 1 157 ? 34.750 45.092 0.056   1.00 74.20  ? 372 TYR   A CD2 1 
ATOM   986  C CE1 . TYR   A 1 157 ? 33.206 47.325 0.514   1.00 71.78  ? 372 TYR   A CE1 1 
ATOM   987  C CE2 . TYR   A 1 157 ? 33.595 44.999 0.837   1.00 72.80  ? 372 TYR   A CE2 1 
ATOM   988  C CZ  . TYR   A 1 157 ? 32.830 46.125 1.057   1.00 72.35  ? 372 TYR   A CZ  1 
ATOM   989  O OH  . TYR   A 1 157 ? 31.682 46.081 1.820   1.00 72.16  ? 372 TYR   A OH  1 
ATOM   990  N N   . ARG   A 1 158 ? 39.970 46.763 -1.015  1.00 75.59  ? 373 ARG   A N   1 
ATOM   991  C CA  . ARG   A 1 158 ? 41.217 47.078 -1.701  1.00 74.89  ? 373 ARG   A CA  1 
ATOM   992  C C   . ARG   A 1 158 ? 41.698 45.861 -2.472  1.00 74.34  ? 373 ARG   A C   1 
ATOM   993  O O   . ARG   A 1 158 ? 41.934 44.803 -1.879  1.00 75.34  ? 373 ARG   A O   1 
ATOM   994  C CB  . ARG   A 1 158 ? 42.290 47.525 -0.714  1.00 76.28  ? 373 ARG   A CB  1 
ATOM   995  C CG  . ARG   A 1 158 ? 41.996 48.854 -0.042  1.00 75.99  ? 373 ARG   A CG  1 
ATOM   996  C CD  . ARG   A 1 158 ? 43.284 49.530 0.372   1.00 75.89  ? 373 ARG   A CD  1 
ATOM   997  N NE  . ARG   A 1 158 ? 42.996 50.813 0.988   1.00 79.02  ? 373 ARG   A NE  1 
ATOM   998  C CZ  . ARG   A 1 158 ? 42.679 50.958 2.265   1.00 79.68  ? 373 ARG   A CZ  1 
ATOM   999  N NH1 . ARG   A 1 158 ? 42.658 49.924 3.090   1.00 79.38  ? 373 ARG   A NH1 1 
ATOM   1000 N NH2 . ARG   A 1 158 ? 42.374 52.169 2.725   1.00 80.51  ? 373 ARG   A NH2 1 
ATOM   1001 N N   . LEU   A 1 159 ? 41.838 46.017 -3.786  1.00 73.25  ? 374 LEU   A N   1 
ATOM   1002 C CA  . LEU   A 1 159 ? 42.446 45.025 -4.675  1.00 71.94  ? 374 LEU   A CA  1 
ATOM   1003 C C   . LEU   A 1 159 ? 43.616 45.731 -5.370  1.00 71.24  ? 374 LEU   A C   1 
ATOM   1004 O O   . LEU   A 1 159 ? 43.504 46.202 -6.499  1.00 70.71  ? 374 LEU   A O   1 
ATOM   1005 C CB  . LEU   A 1 159 ? 41.397 44.464 -5.683  1.00 71.76  ? 374 LEU   A CB  1 
ATOM   1006 C CG  . LEU   A 1 159 ? 40.077 43.934 -5.086  1.00 72.53  ? 374 LEU   A CG  1 
ATOM   1007 C CD1 . LEU   A 1 159 ? 39.067 45.050 -4.854  1.00 71.43  ? 374 LEU   A CD1 1 
ATOM   1008 C CD2 . LEU   A 1 159 ? 39.483 42.887 -6.014  1.00 72.46  ? 374 LEU   A CD2 1 
ATOM   1009 N N   . LEU   A 1 160 ? 44.742 45.810 -4.671  1.00 72.03  ? 375 LEU   A N   1 
ATOM   1010 C CA  . LEU   A 1 160 ? 45.859 46.669 -5.027  1.00 73.00  ? 375 LEU   A CA  1 
ATOM   1011 C C   . LEU   A 1 160 ? 47.013 45.850 -5.590  1.00 73.40  ? 375 LEU   A C   1 
ATOM   1012 O O   . LEU   A 1 160 ? 47.245 44.707 -5.184  1.00 73.38  ? 375 LEU   A O   1 
ATOM   1013 C CB  . LEU   A 1 160 ? 46.339 47.434 -3.793  1.00 74.07  ? 375 LEU   A CB  1 
ATOM   1014 C CG  . LEU   A 1 160 ? 45.322 48.368 -3.144  1.00 74.91  ? 375 LEU   A CG  1 
ATOM   1015 C CD1 . LEU   A 1 160 ? 46.020 49.519 -2.406  1.00 75.00  ? 375 LEU   A CD1 1 
ATOM   1016 C CD2 . LEU   A 1 160 ? 44.383 48.905 -4.235  1.00 72.40  ? 375 LEU   A CD2 1 
ATOM   1017 N N   . ARG   A 1 161 ? 47.782 46.441 -6.485  1.00 74.49  ? 376 ARG   A N   1 
ATOM   1018 C CA  . ARG   A 1 161 ? 48.948 45.778 -7.032  1.00 75.28  ? 376 ARG   A CA  1 
ATOM   1019 C C   . ARG   A 1 161 ? 48.623 44.407 -7.611  1.00 73.39  ? 376 ARG   A C   1 
ATOM   1020 O O   . ARG   A 1 161 ? 49.396 43.486 -7.555  1.00 73.92  ? 376 ARG   A O   1 
ATOM   1021 C CB  . ARG   A 1 161 ? 50.046 45.701 -5.977  1.00 77.89  ? 376 ARG   A CB  1 
ATOM   1022 C CG  . ARG   A 1 161 ? 51.316 45.014 -6.434  1.00 82.41  ? 376 ARG   A CG  1 
ATOM   1023 C CD  . ARG   A 1 161 ? 52.507 45.324 -5.560  1.00 86.46  ? 376 ARG   A CD  1 
ATOM   1024 N NE  . ARG   A 1 161 ? 53.292 46.404 -6.118  1.00 90.93  ? 376 ARG   A NE  1 
ATOM   1025 C CZ  . ARG   A 1 161 ? 52.952 47.674 -6.025  1.00 89.87  ? 376 ARG   A CZ  1 
ATOM   1026 N NH1 . ARG   A 1 161 ? 51.842 48.003 -5.403  1.00 86.45  ? 376 ARG   A NH1 1 
ATOM   1027 N NH2 . ARG   A 1 161 ? 53.719 48.608 -6.558  1.00 90.46  ? 376 ARG   A NH2 1 
ATOM   1028 N N   . SER   A 1 162 ? 47.465 44.279 -8.203  1.00 72.80  ? 377 SER   A N   1 
ATOM   1029 C CA  . SER   A 1 162 ? 47.091 43.003 -8.801  1.00 75.14  ? 377 SER   A CA  1 
ATOM   1030 C C   . SER   A 1 162 ? 47.834 42.781 -10.119 1.00 77.44  ? 377 SER   A C   1 
ATOM   1031 O O   . SER   A 1 162 ? 47.755 43.631 -11.015 1.00 72.65  ? 377 SER   A O   1 
ATOM   1032 C CB  . SER   A 1 162 ? 45.580 42.962 -9.025  1.00 75.65  ? 377 SER   A CB  1 
ATOM   1033 O OG  . SER   A 1 162 ? 45.147 41.639 -9.296  1.00 78.34  ? 377 SER   A OG  1 
ATOM   1034 N N   . PRO   A 1 163 ? 48.547 41.671 -10.289 1.00 78.17  ? 378 PRO   A N   1 
ATOM   1035 C CA  . PRO   A 1 163 ? 49.211 41.420 -11.571 1.00 78.30  ? 378 PRO   A CA  1 
ATOM   1036 C C   . PRO   A 1 163 ? 48.253 41.567 -12.743 1.00 79.25  ? 378 PRO   A C   1 
ATOM   1037 O O   . PRO   A 1 163 ? 47.140 41.019 -12.749 1.00 78.43  ? 378 PRO   A O   1 
ATOM   1038 C CB  . PRO   A 1 163 ? 49.737 39.986 -11.437 1.00 77.84  ? 378 PRO   A CB  1 
ATOM   1039 C CG  . PRO   A 1 163 ? 49.568 39.598 -9.993  1.00 78.42  ? 378 PRO   A CG  1 
ATOM   1040 C CD  . PRO   A 1 163 ? 48.883 40.679 -9.256  1.00 77.09  ? 378 PRO   A CD  1 
ATOM   1041 N N   . MET   A 1 164 ? 48.682 42.378 -13.714 1.00 78.51  ? 379 MET   A N   1 
ATOM   1042 C CA  . MET   A 1 164 ? 48.077 42.402 -15.032 1.00 79.06  ? 379 MET   A CA  1 
ATOM   1043 C C   . MET   A 1 164 ? 48.343 41.078 -15.732 1.00 79.76  ? 379 MET   A C   1 
ATOM   1044 O O   . MET   A 1 164 ? 49.488 40.608 -15.775 1.00 79.72  ? 379 MET   A O   1 
ATOM   1045 C CB  . MET   A 1 164 ? 48.667 43.546 -15.848 1.00 77.82  ? 379 MET   A CB  1 
ATOM   1046 C CG  . MET   A 1 164 ? 47.720 44.181 -16.826 1.00 79.73  ? 379 MET   A CG  1 
ATOM   1047 S SD  . MET   A 1 164 ? 48.572 45.453 -17.765 1.00 73.44  ? 379 MET   A SD  1 
ATOM   1048 C CE  . MET   A 1 164 ? 47.973 46.867 -16.835 1.00 71.85  ? 379 MET   A CE  1 
ATOM   1049 N N   . CYS   A 1 165 ? 47.291 40.474 -16.285 1.00 77.29  ? 380 CYS   A N   1 
ATOM   1050 C CA  . CYS   A 1 165 ? 47.450 39.192 -16.969 1.00 81.33  ? 380 CYS   A CA  1 
ATOM   1051 C C   . CYS   A 1 165 ? 48.431 39.302 -18.133 1.00 84.78  ? 380 CYS   A C   1 
ATOM   1052 O O   . CYS   A 1 165 ? 48.569 40.353 -18.769 1.00 82.12  ? 380 CYS   A O   1 
ATOM   1053 C CB  . CYS   A 1 165 ? 46.103 38.677 -17.481 1.00 82.73  ? 380 CYS   A CB  1 
ATOM   1054 S SG  . CYS   A 1 165 ? 45.086 39.944 -18.262 1.00 89.70  ? 380 CYS   A SG  1 
ATOM   1055 N N   . GLU   A 1 166 ? 49.122 38.193 -18.397 1.00 94.49  ? 381 GLU   A N   1 
ATOM   1056 C CA  . GLU   A 1 166 ? 50.068 38.130 -19.502 1.00 95.51  ? 381 GLU   A CA  1 
ATOM   1057 C C   . GLU   A 1 166 ? 49.479 38.739 -20.770 1.00 97.00  ? 381 GLU   A C   1 
ATOM   1058 O O   . GLU   A 1 166 ? 50.113 39.578 -21.421 1.00 95.10  ? 381 GLU   A O   1 
ATOM   1059 C CB  . GLU   A 1 166 ? 50.482 36.673 -19.727 1.00 102.65 ? 381 GLU   A CB  1 
ATOM   1060 C CG  . GLU   A 1 166 ? 50.813 36.296 -21.168 1.00 106.98 ? 381 GLU   A CG  1 
ATOM   1061 C CD  . GLU   A 1 166 ? 50.925 34.786 -21.379 1.00 113.06 ? 381 GLU   A CD  1 
ATOM   1062 O OE1 . GLU   A 1 166 ? 50.945 34.038 -20.376 1.00 114.64 ? 381 GLU   A OE1 1 
ATOM   1063 O OE2 . GLU   A 1 166 ? 50.987 34.339 -22.547 1.00 116.66 ? 381 GLU   A OE2 1 
ATOM   1064 N N   . TYR   A 1 167 ? 48.250 38.347 -21.121 1.00 88.02  ? 382 TYR   A N   1 
ATOM   1065 C CA  . TYR   A 1 167 ? 47.653 38.821 -22.365 1.00 83.69  ? 382 TYR   A CA  1 
ATOM   1066 C C   . TYR   A 1 167 ? 47.677 40.345 -22.451 1.00 83.09  ? 382 TYR   A C   1 
ATOM   1067 O O   . TYR   A 1 167 ? 48.009 40.903 -23.502 1.00 80.35  ? 382 TYR   A O   1 
ATOM   1068 C CB  . TYR   A 1 167 ? 46.220 38.283 -22.521 1.00 81.05  ? 382 TYR   A CB  1 
ATOM   1069 C CG  . TYR   A 1 167 ? 45.510 38.790 -23.767 1.00 80.25  ? 382 TYR   A CG  1 
ATOM   1070 C CD1 . TYR   A 1 167 ? 45.652 38.142 -24.995 1.00 80.57  ? 382 TYR   A CD1 1 
ATOM   1071 C CD2 . TYR   A 1 167 ? 44.727 39.934 -23.725 1.00 78.19  ? 382 TYR   A CD2 1 
ATOM   1072 C CE1 . TYR   A 1 167 ? 45.017 38.616 -26.137 1.00 78.75  ? 382 TYR   A CE1 1 
ATOM   1073 C CE2 . TYR   A 1 167 ? 44.095 40.416 -24.866 1.00 77.50  ? 382 TYR   A CE2 1 
ATOM   1074 C CZ  . TYR   A 1 167 ? 44.244 39.757 -26.066 1.00 78.21  ? 382 TYR   A CZ  1 
ATOM   1075 O OH  . TYR   A 1 167 ? 43.611 40.261 -27.184 1.00 79.84  ? 382 TYR   A OH  1 
ATOM   1076 N N   . LEU   A 1 168 ? 47.355 41.041 -21.357 1.00 84.02  ? 383 LEU   A N   1 
ATOM   1077 C CA  . LEU   A 1 168 ? 47.328 42.499 -21.423 1.00 83.20  ? 383 LEU   A CA  1 
ATOM   1078 C C   . LEU   A 1 168 ? 48.729 43.071 -21.562 1.00 82.83  ? 383 LEU   A C   1 
ATOM   1079 O O   . LEU   A 1 168 ? 48.935 44.048 -22.292 1.00 79.51  ? 383 LEU   A O   1 
ATOM   1080 C CB  . LEU   A 1 168 ? 46.649 43.082 -20.186 1.00 80.97  ? 383 LEU   A CB  1 
ATOM   1081 C CG  . LEU   A 1 168 ? 45.128 43.241 -20.193 1.00 79.25  ? 383 LEU   A CG  1 
ATOM   1082 C CD1 . LEU   A 1 168 ? 44.661 44.357 -19.260 1.00 74.77  ? 383 LEU   A CD1 1 
ATOM   1083 C CD2 . LEU   A 1 168 ? 44.623 43.486 -21.585 1.00 78.04  ? 383 LEU   A CD2 1 
ATOM   1084 N N   . VAL   A 1 169 ? 49.698 42.500 -20.846 1.00 83.84  ? 384 VAL   A N   1 
ATOM   1085 C CA  . VAL   A 1 169 ? 51.064 43.002 -20.935 1.00 86.43  ? 384 VAL   A CA  1 
ATOM   1086 C C   . VAL   A 1 169 ? 51.558 42.918 -22.375 1.00 82.97  ? 384 VAL   A C   1 
ATOM   1087 O O   . VAL   A 1 169 ? 51.963 43.925 -22.965 1.00 80.58  ? 384 VAL   A O   1 
ATOM   1088 C CB  . VAL   A 1 169 ? 51.989 42.246 -19.969 1.00 85.87  ? 384 VAL   A CB  1 
ATOM   1089 C CG1 . VAL   A 1 169 ? 53.310 42.983 -19.828 1.00 79.50  ? 384 VAL   A CG1 1 
ATOM   1090 C CG2 . VAL   A 1 169 ? 51.317 42.079 -18.601 1.00 86.21  ? 384 VAL   A CG2 1 
ATOM   1091 N N   . ASN   A 1 170 ? 51.507 41.713 -22.961 1.00 81.66  ? 385 ASN   A N   1 
ATOM   1092 C CA  . ASN   A 1 170 ? 51.893 41.505 -24.359 1.00 79.62  ? 385 ASN   A CA  1 
ATOM   1093 C C   . ASN   A 1 170 ? 51.155 42.460 -25.299 1.00 77.73  ? 385 ASN   A C   1 
ATOM   1094 O O   . ASN   A 1 170 ? 51.768 43.118 -26.144 1.00 73.92  ? 385 ASN   A O   1 
ATOM   1095 C CB  . ASN   A 1 170 ? 51.636 40.047 -24.778 1.00 83.84  ? 385 ASN   A CB  1 
ATOM   1096 C CG  . ASN   A 1 170 ? 52.201 39.016 -23.790 1.00 92.71  ? 385 ASN   A CG  1 
ATOM   1097 O OD1 . ASN   A 1 170 ? 53.371 39.089 -23.391 1.00 99.01  ? 385 ASN   A OD1 1 
ATOM   1098 N ND2 . ASN   A 1 170 ? 51.376 38.031 -23.413 1.00 95.40  ? 385 ASN   A ND2 1 
ATOM   1099 N N   . PHE   A 1 171 ? 49.830 42.542 -25.163 1.00 77.44  ? 386 PHE   A N   1 
ATOM   1100 C CA  . PHE   A 1 171 ? 49.042 43.450 -25.986 1.00 75.19  ? 386 PHE   A CA  1 
ATOM   1101 C C   . PHE   A 1 171 ? 49.538 44.887 -25.856 1.00 78.19  ? 386 PHE   A C   1 
ATOM   1102 O O   . PHE   A 1 171 ? 49.737 45.583 -26.866 1.00 73.43  ? 386 PHE   A O   1 
ATOM   1103 C CB  . PHE   A 1 171 ? 47.566 43.349 -25.600 1.00 72.59  ? 386 PHE   A CB  1 
ATOM   1104 C CG  . PHE   A 1 171 ? 46.670 44.286 -26.368 1.00 70.19  ? 386 PHE   A CG  1 
ATOM   1105 C CD1 . PHE   A 1 171 ? 46.600 44.223 -27.754 1.00 68.68  ? 386 PHE   A CD1 1 
ATOM   1106 C CD2 . PHE   A 1 171 ? 45.913 45.234 -25.709 1.00 67.93  ? 386 PHE   A CD2 1 
ATOM   1107 C CE1 . PHE   A 1 171 ? 45.780 45.087 -28.467 1.00 65.42  ? 386 PHE   A CE1 1 
ATOM   1108 C CE2 . PHE   A 1 171 ? 45.094 46.095 -26.404 1.00 65.52  ? 386 PHE   A CE2 1 
ATOM   1109 C CZ  . PHE   A 1 171 ? 45.029 46.020 -27.793 1.00 65.97  ? 386 PHE   A CZ  1 
ATOM   1110 N N   . LEU   A 1 172 ? 49.724 45.360 -24.616 1.00 74.39  ? 387 LEU   A N   1 
ATOM   1111 C CA  . LEU   A 1 172 ? 50.255 46.704 -24.427 1.00 77.97  ? 387 LEU   A CA  1 
ATOM   1112 C C   . LEU   A 1 172 ? 51.617 46.855 -25.086 1.00 73.63  ? 387 LEU   A C   1 
ATOM   1113 O O   . LEU   A 1 172 ? 51.908 47.892 -25.683 1.00 73.38  ? 387 LEU   A O   1 
ATOM   1114 C CB  . LEU   A 1 172 ? 50.358 47.048 -22.940 1.00 76.35  ? 387 LEU   A CB  1 
ATOM   1115 C CG  . LEU   A 1 172 ? 49.132 47.518 -22.153 1.00 73.91  ? 387 LEU   A CG  1 
ATOM   1116 C CD1 . LEU   A 1 172 ? 49.540 47.808 -20.709 1.00 72.58  ? 387 LEU   A CD1 1 
ATOM   1117 C CD2 . LEU   A 1 172 ? 48.469 48.733 -22.788 1.00 70.10  ? 387 LEU   A CD2 1 
ATOM   1118 N N   . HIS   A 1 173 ? 52.475 45.845 -24.970 1.00 72.14  ? 388 HIS   A N   1 
ATOM   1119 C CA  . HIS   A 1 173 ? 53.817 45.966 -25.523 1.00 73.68  ? 388 HIS   A CA  1 
ATOM   1120 C C   . HIS   A 1 173 ? 53.771 46.072 -27.044 1.00 73.84  ? 388 HIS   A C   1 
ATOM   1121 O O   . HIS   A 1 173 ? 54.535 46.837 -27.642 1.00 73.04  ? 388 HIS   A O   1 
ATOM   1122 C CB  . HIS   A 1 173 ? 54.666 44.783 -25.054 1.00 74.73  ? 388 HIS   A CB  1 
ATOM   1123 C CG  . HIS   A 1 173 ? 55.909 44.548 -25.860 1.00 81.08  ? 388 HIS   A CG  1 
ATOM   1124 N ND1 . HIS   A 1 173 ? 56.142 43.371 -26.541 1.00 84.40  ? 388 HIS   A ND1 1 
ATOM   1125 C CD2 . HIS   A 1 173 ? 56.999 45.325 -26.076 1.00 85.15  ? 388 HIS   A CD2 1 
ATOM   1126 C CE1 . HIS   A 1 173 ? 57.313 43.437 -27.153 1.00 84.76  ? 388 HIS   A CE1 1 
ATOM   1127 N NE2 . HIS   A 1 173 ? 57.853 44.613 -26.887 1.00 85.35  ? 388 HIS   A NE2 1 
ATOM   1128 N N   . LYS   A 1 174 ? 52.857 45.338 -27.687 1.00 73.23  ? 389 LYS   A N   1 
ATOM   1129 C CA  . LYS   A 1 174 ? 52.653 45.503 -29.123 1.00 72.84  ? 389 LYS   A CA  1 
ATOM   1130 C C   . LYS   A 1 174 ? 52.067 46.863 -29.451 1.00 72.41  ? 389 LYS   A C   1 
ATOM   1131 O O   . LYS   A 1 174 ? 52.464 47.492 -30.430 1.00 69.93  ? 389 LYS   A O   1 
ATOM   1132 C CB  . LYS   A 1 174 ? 51.718 44.426 -29.651 1.00 70.80  ? 389 LYS   A CB  1 
ATOM   1133 C CG  . LYS   A 1 174 ? 52.359 43.083 -29.881 1.00 70.01  ? 389 LYS   A CG  1 
ATOM   1134 C CD  . LYS   A 1 174 ? 51.316 42.037 -29.624 1.00 72.38  ? 389 LYS   A CD  1 
ATOM   1135 C CE  . LYS   A 1 174 ? 51.813 40.666 -29.943 1.00 71.45  ? 389 LYS   A CE  1 
ATOM   1136 N NZ  . LYS   A 1 174 ? 50.652 39.776 -29.740 1.00 73.44  ? 389 LYS   A NZ  1 
ATOM   1137 N N   . LEU   A 1 175 ? 51.101 47.319 -28.662 1.00 72.11  ? 390 LEU   A N   1 
ATOM   1138 C CA  . LEU   A 1 175 ? 50.366 48.526 -29.002 1.00 70.45  ? 390 LEU   A CA  1 
ATOM   1139 C C   . LEU   A 1 175 ? 51.271 49.748 -28.943 1.00 67.72  ? 390 LEU   A C   1 
ATOM   1140 O O   . LEU   A 1 175 ? 51.190 50.640 -29.796 1.00 67.28  ? 390 LEU   A O   1 
ATOM   1141 C CB  . LEU   A 1 175 ? 49.179 48.664 -28.056 1.00 71.24  ? 390 LEU   A CB  1 
ATOM   1142 C CG  . LEU   A 1 175 ? 47.945 49.519 -28.343 1.00 66.73  ? 390 LEU   A CG  1 
ATOM   1143 C CD1 . LEU   A 1 175 ? 47.294 49.109 -29.644 1.00 63.38  ? 390 LEU   A CD1 1 
ATOM   1144 C CD2 . LEU   A 1 175 ? 46.967 49.357 -27.146 1.00 64.54  ? 390 LEU   A CD2 1 
ATOM   1145 N N   . ARG   A 1 176 ? 52.158 49.793 -27.954 1.00 68.26  ? 391 ARG   A N   1 
ATOM   1146 C CA  . ARG   A 1 176 ? 53.056 50.930 -27.796 1.00 68.81  ? 391 ARG   A CA  1 
ATOM   1147 C C   . ARG   A 1 176 ? 53.934 51.139 -29.026 1.00 68.69  ? 391 ARG   A C   1 
ATOM   1148 O O   . ARG   A 1 176 ? 54.472 52.239 -29.211 1.00 68.50  ? 391 ARG   A O   1 
ATOM   1149 C CB  . ARG   A 1 176 ? 53.945 50.719 -26.571 1.00 71.25  ? 391 ARG   A CB  1 
ATOM   1150 C CG  . ARG   A 1 176 ? 54.657 49.368 -26.567 1.00 72.26  ? 391 ARG   A CG  1 
ATOM   1151 C CD  . ARG   A 1 176 ? 55.681 49.246 -25.425 1.00 74.60  ? 391 ARG   A CD  1 
ATOM   1152 N NE  . ARG   A 1 176 ? 56.183 50.541 -24.965 1.00 77.05  ? 391 ARG   A NE  1 
ATOM   1153 C CZ  . ARG   A 1 176 ? 57.001 50.701 -23.931 1.00 81.53  ? 391 ARG   A CZ  1 
ATOM   1154 N NH1 . ARG   A 1 176 ? 57.515 49.662 -23.291 1.00 83.78  ? 391 ARG   A NH1 1 
ATOM   1155 N NH2 . ARG   A 1 176 ? 57.315 51.934 -23.533 1.00 81.03  ? 391 ARG   A NH2 1 
ATOM   1156 N N   . GLN   A 1 177 ? 54.083 50.112 -29.873 1.00 68.29  ? 392 GLN   A N   1 
ATOM   1157 C CA  . GLN   A 1 177 ? 54.999 50.131 -30.998 1.00 67.79  ? 392 GLN   A CA  1 
ATOM   1158 C C   . GLN   A 1 177 ? 54.347 50.659 -32.266 1.00 67.72  ? 392 GLN   A C   1 
ATOM   1159 O O   . GLN   A 1 177 ? 55.055 51.046 -33.198 1.00 67.63  ? 392 GLN   A O   1 
ATOM   1160 C CB  . GLN   A 1 177 ? 55.507 48.716 -31.297 1.00 69.79  ? 392 GLN   A CB  1 
ATOM   1161 C CG  . GLN   A 1 177 ? 56.487 48.125 -30.273 1.00 72.20  ? 392 GLN   A CG  1 
ATOM   1162 C CD  . GLN   A 1 177 ? 56.712 46.642 -30.519 1.00 78.21  ? 392 GLN   A CD  1 
ATOM   1163 O OE1 . GLN   A 1 177 ? 56.234 46.085 -31.521 1.00 78.82  ? 392 GLN   A OE1 1 
ATOM   1164 N NE2 . GLN   A 1 177 ? 57.447 45.993 -29.617 1.00 83.68  ? 392 GLN   A NE2 1 
ATOM   1165 N N   . LEU   A 1 178 ? 53.023 50.653 -32.335 1.00 66.56  ? 393 LEU   A N   1 
ATOM   1166 C CA  . LEU   A 1 178 ? 52.353 51.163 -33.513 1.00 66.47  ? 393 LEU   A CA  1 
ATOM   1167 C C   . LEU   A 1 178 ? 52.854 52.575 -33.801 1.00 65.81  ? 393 LEU   A C   1 
ATOM   1168 O O   . LEU   A 1 178 ? 53.106 53.347 -32.862 1.00 64.62  ? 393 LEU   A O   1 
ATOM   1169 C CB  . LEU   A 1 178 ? 50.842 51.157 -33.311 1.00 65.11  ? 393 LEU   A CB  1 
ATOM   1170 C CG  . LEU   A 1 178 ? 50.197 49.837 -33.718 1.00 64.21  ? 393 LEU   A CG  1 
ATOM   1171 C CD1 . LEU   A 1 178 ? 51.127 48.708 -33.368 1.00 65.34  ? 393 LEU   A CD1 1 
ATOM   1172 C CD2 . LEU   A 1 178 ? 48.885 49.675 -33.004 1.00 63.95  ? 393 LEU   A CD2 1 
ATOM   1173 N N   . PRO   A 1 179 ? 53.044 52.933 -35.080 1.00 64.07  ? 394 PRO   A N   1 
ATOM   1174 C CA  . PRO   A 1 179 ? 53.640 54.238 -35.403 1.00 61.96  ? 394 PRO   A CA  1 
ATOM   1175 C C   . PRO   A 1 179 ? 52.703 55.421 -35.250 1.00 62.32  ? 394 PRO   A C   1 
ATOM   1176 O O   . PRO   A 1 179 ? 53.187 56.555 -35.094 1.00 62.39  ? 394 PRO   A O   1 
ATOM   1177 C CB  . PRO   A 1 179 ? 54.070 54.075 -36.871 1.00 63.70  ? 394 PRO   A CB  1 
ATOM   1178 C CG  . PRO   A 1 179 ? 53.187 52.953 -37.415 1.00 63.16  ? 394 PRO   A CG  1 
ATOM   1179 C CD  . PRO   A 1 179 ? 53.007 52.020 -36.241 1.00 62.95  ? 394 PRO   A CD  1 
ATOM   1180 N N   . GLU   A 1 180 ? 51.392 55.216 -35.281 1.00 60.80  ? 395 GLU   A N   1 
ATOM   1181 C CA  . GLU   A 1 180 ? 50.466 56.331 -35.337 1.00 59.19  ? 395 GLU   A CA  1 
ATOM   1182 C C   . GLU   A 1 180 ? 49.385 56.124 -34.296 1.00 60.80  ? 395 GLU   A C   1 
ATOM   1183 O O   . GLU   A 1 180 ? 48.880 55.011 -34.131 1.00 61.30  ? 395 GLU   A O   1 
ATOM   1184 C CB  . GLU   A 1 180 ? 49.806 56.469 -36.723 1.00 58.36  ? 395 GLU   A CB  1 
ATOM   1185 C CG  . GLU   A 1 180 ? 50.729 56.774 -37.874 1.00 61.34  ? 395 GLU   A CG  1 
ATOM   1186 C CD  . GLU   A 1 180 ? 51.451 58.088 -37.720 1.00 61.70  ? 395 GLU   A CD  1 
ATOM   1187 O OE1 . GLU   A 1 180 ? 52.489 58.265 -38.396 1.00 60.12  ? 395 GLU   A OE1 1 
ATOM   1188 O OE2 . GLU   A 1 180 ? 50.995 58.939 -36.912 1.00 60.83  ? 395 GLU   A OE2 1 
ATOM   1189 N N   . ARG   A 1 181 ? 48.998 57.195 -33.613 1.00 58.80  ? 396 ARG   A N   1 
ATOM   1190 C CA  . ARG   A 1 181 ? 47.939 57.022 -32.630 1.00 60.84  ? 396 ARG   A CA  1 
ATOM   1191 C C   . ARG   A 1 181 ? 46.643 56.580 -33.288 1.00 60.05  ? 396 ARG   A C   1 
ATOM   1192 O O   . ARG   A 1 181 ? 45.873 55.817 -32.689 1.00 56.91  ? 396 ARG   A O   1 
ATOM   1193 C CB  . ARG   A 1 181 ? 47.745 58.304 -31.812 1.00 62.51  ? 396 ARG   A CB  1 
ATOM   1194 C CG  . ARG   A 1 181 ? 48.871 58.598 -30.813 1.00 64.02  ? 396 ARG   A CG  1 
ATOM   1195 C CD  . ARG   A 1 181 ? 48.544 59.829 -29.952 1.00 68.40  ? 396 ARG   A CD  1 
ATOM   1196 N NE  . ARG   A 1 181 ? 47.234 60.389 -30.285 1.00 68.45  ? 396 ARG   A NE  1 
ATOM   1197 C CZ  . ARG   A 1 181 ? 47.061 61.431 -31.093 1.00 68.35  ? 396 ARG   A CZ  1 
ATOM   1198 N NH1 . ARG   A 1 181 ? 48.090 62.021 -31.683 1.00 71.32  ? 396 ARG   A NH1 1 
ATOM   1199 N NH2 . ARG   A 1 181 ? 45.828 61.885 -31.323 1.00 69.99  ? 396 ARG   A NH2 1 
ATOM   1200 N N   . TYR   A 1 182 ? 46.395 57.003 -34.527 1.00 55.58  ? 397 TYR   A N   1 
ATOM   1201 C CA  . TYR   A 1 182 ? 45.173 56.537 -35.169 1.00 58.01  ? 397 TYR   A CA  1 
ATOM   1202 C C   . TYR   A 1 182 ? 45.219 55.041 -35.431 1.00 57.63  ? 397 TYR   A C   1 
ATOM   1203 O O   . TYR   A 1 182 ? 44.158 54.414 -35.527 1.00 56.34  ? 397 TYR   A O   1 
ATOM   1204 C CB  . TYR   A 1 182 ? 44.875 57.306 -36.467 1.00 57.14  ? 397 TYR   A CB  1 
ATOM   1205 C CG  . TYR   A 1 182 ? 45.676 56.878 -37.697 1.00 58.16  ? 397 TYR   A CG  1 
ATOM   1206 C CD1 . TYR   A 1 182 ? 45.296 55.775 -38.447 1.00 58.62  ? 397 TYR   A CD1 1 
ATOM   1207 C CD2 . TYR   A 1 182 ? 46.750 57.640 -38.152 1.00 58.67  ? 397 TYR   A CD2 1 
ATOM   1208 C CE1 . TYR   A 1 182 ? 46.005 55.398 -39.568 1.00 60.62  ? 397 TYR   A CE1 1 
ATOM   1209 C CE2 . TYR   A 1 182 ? 47.466 57.283 -39.281 1.00 59.10  ? 397 TYR   A CE2 1 
ATOM   1210 C CZ  . TYR   A 1 182 ? 47.085 56.170 -39.984 1.00 61.48  ? 397 TYR   A CZ  1 
ATOM   1211 O OH  . TYR   A 1 182 ? 47.808 55.795 -41.083 1.00 59.78  ? 397 TYR   A OH  1 
ATOM   1212 N N   . MET   A 1 183 ? 46.407 54.445 -35.516 1.00 54.42  ? 398 MET   A N   1 
ATOM   1213 C CA  . MET   A 1 183 ? 46.411 53.005 -35.700 1.00 60.57  ? 398 MET   A CA  1 
ATOM   1214 C C   . MET   A 1 183 ? 46.174 52.288 -34.382 1.00 58.10  ? 398 MET   A C   1 
ATOM   1215 O O   . MET   A 1 183 ? 45.549 51.229 -34.373 1.00 56.35  ? 398 MET   A O   1 
ATOM   1216 C CB  . MET   A 1 183 ? 47.701 52.544 -36.366 1.00 58.81  ? 398 MET   A CB  1 
ATOM   1217 C CG  . MET   A 1 183 ? 47.936 53.140 -37.741 1.00 60.09  ? 398 MET   A CG  1 
ATOM   1218 S SD  . MET   A 1 183 ? 49.465 52.539 -38.404 1.00 56.47  ? 398 MET   A SD  1 
ATOM   1219 C CE  . MET   A 1 183 ? 49.522 53.482 -39.950 1.00 64.74  ? 398 MET   A CE  1 
ATOM   1220 N N   . MET   A 1 184 ? 46.649 52.845 -33.265 1.00 59.45  ? 399 MET   A N   1 
ATOM   1221 C CA  . MET   A 1 184 ? 46.242 52.340 -31.948 1.00 60.86  ? 399 MET   A CA  1 
ATOM   1222 C C   . MET   A 1 184 ? 44.732 52.470 -31.758 1.00 59.07  ? 399 MET   A C   1 
ATOM   1223 O O   . MET   A 1 184 ? 44.050 51.509 -31.390 1.00 54.35  ? 399 MET   A O   1 
ATOM   1224 C CB  . MET   A 1 184 ? 46.999 53.091 -30.859 1.00 59.03  ? 399 MET   A CB  1 
ATOM   1225 C CG  . MET   A 1 184 ? 48.477 53.116 -31.107 1.00 60.90  ? 399 MET   A CG  1 
ATOM   1226 S SD  . MET   A 1 184 ? 49.273 54.182 -29.936 1.00 53.71  ? 399 MET   A SD  1 
ATOM   1227 C CE  . MET   A 1 184 ? 50.998 53.803 -30.179 1.00 65.71  ? 399 MET   A CE  1 
ATOM   1228 N N   . ASN   A 1 185 ? 44.178 53.635 -32.087 1.00 56.98  ? 400 ASN   A N   1 
ATOM   1229 C CA  . ASN   A 1 185 ? 42.730 53.769 -32.022 1.00 57.90  ? 400 ASN   A CA  1 
ATOM   1230 C C   . ASN   A 1 185 ? 42.045 52.697 -32.841 1.00 60.07  ? 400 ASN   A C   1 
ATOM   1231 O O   . ASN   A 1 185 ? 41.104 52.052 -32.368 1.00 57.31  ? 400 ASN   A O   1 
ATOM   1232 C CB  . ASN   A 1 185 ? 42.317 55.158 -32.469 1.00 59.08  ? 400 ASN   A CB  1 
ATOM   1233 C CG  . ASN   A 1 185 ? 42.558 56.161 -31.376 1.00 60.82  ? 400 ASN   A CG  1 
ATOM   1234 O OD1 . ASN   A 1 185 ? 42.891 55.751 -30.258 1.00 56.38  ? 400 ASN   A OD1 1 
ATOM   1235 N ND2 . ASN   A 1 185 ? 42.405 57.448 -31.664 1.00 57.78  ? 400 ASN   A ND2 1 
ATOM   1236 N N   . SER   A 1 186 ? 42.539 52.445 -34.059 1.00 57.39  ? 401 SER   A N   1 
ATOM   1237 C CA  . SER   A 1 186 ? 41.910 51.435 -34.899 1.00 59.76  ? 401 SER   A CA  1 
ATOM   1238 C C   . SER   A 1 186 ? 41.972 50.073 -34.231 1.00 57.40  ? 401 SER   A C   1 
ATOM   1239 O O   . SER   A 1 186 ? 40.984 49.330 -34.209 1.00 56.24  ? 401 SER   A O   1 
ATOM   1240 C CB  . SER   A 1 186 ? 42.580 51.395 -36.270 1.00 62.91  ? 401 SER   A CB  1 
ATOM   1241 O OG  . SER   A 1 186 ? 42.111 52.464 -37.078 1.00 62.65  ? 401 SER   A OG  1 
ATOM   1242 N N   . VAL   A 1 187 ? 43.131 49.726 -33.673 1.00 56.05  ? 402 VAL   A N   1 
ATOM   1243 C CA  . VAL   A 1 187 ? 43.288 48.433 -33.017 1.00 63.07  ? 402 VAL   A CA  1 
ATOM   1244 C C   . VAL   A 1 187 ? 42.419 48.351 -31.764 1.00 62.54  ? 402 VAL   A C   1 
ATOM   1245 O O   . VAL   A 1 187 ? 41.898 47.287 -31.422 1.00 59.50  ? 402 VAL   A O   1 
ATOM   1246 C CB  . VAL   A 1 187 ? 44.768 48.183 -32.681 1.00 60.51  ? 402 VAL   A CB  1 
ATOM   1247 C CG1 . VAL   A 1 187 ? 44.898 46.940 -31.756 1.00 60.52  ? 402 VAL   A CG1 1 
ATOM   1248 C CG2 . VAL   A 1 187 ? 45.542 47.987 -33.914 1.00 60.27  ? 402 VAL   A CG2 1 
ATOM   1249 N N   . LEU   A 1 188 ? 42.244 49.471 -31.070 1.00 61.10  ? 403 LEU   A N   1 
ATOM   1250 C CA  . LEU   A 1 188 ? 41.508 49.484 -29.811 1.00 61.13  ? 403 LEU   A CA  1 
ATOM   1251 C C   . LEU   A 1 188 ? 39.996 49.438 -29.991 1.00 59.48  ? 403 LEU   A C   1 
ATOM   1252 O O   . LEU   A 1 188 ? 39.301 48.967 -29.084 1.00 62.02  ? 403 LEU   A O   1 
ATOM   1253 C CB  . LEU   A 1 188 ? 41.879 50.721 -29.006 1.00 58.54  ? 403 LEU   A CB  1 
ATOM   1254 C CG  . LEU   A 1 188 ? 43.297 50.656 -28.474 1.00 58.30  ? 403 LEU   A CG  1 
ATOM   1255 C CD1 . LEU   A 1 188 ? 43.664 52.031 -27.935 1.00 61.18  ? 403 LEU   A CD1 1 
ATOM   1256 C CD2 . LEU   A 1 188 ? 43.389 49.565 -27.393 1.00 61.74  ? 403 LEU   A CD2 1 
ATOM   1257 N N   . GLU   A 1 189 ? 39.461 49.875 -31.135 1.00 60.33  ? 404 GLU   A N   1 
ATOM   1258 C CA  . GLU   A 1 189 ? 38.006 49.868 -31.285 1.00 62.92  ? 404 GLU   A CA  1 
ATOM   1259 C C   . GLU   A 1 189 ? 37.413 48.458 -31.169 1.00 64.98  ? 404 GLU   A C   1 
ATOM   1260 O O   . GLU   A 1 189 ? 36.197 48.329 -30.968 1.00 67.10  ? 404 GLU   A O   1 
ATOM   1261 C CB  . GLU   A 1 189 ? 37.591 50.600 -32.600 1.00 61.72  ? 404 GLU   A CB  1 
ATOM   1262 C CG  . GLU   A 1 189 ? 38.202 50.135 -33.961 1.00 65.41  ? 404 GLU   A CG  1 
ATOM   1263 C CD  . GLU   A 1 189 ? 37.710 50.968 -35.196 1.00 70.75  ? 404 GLU   A CD  1 
ATOM   1264 O OE1 . GLU   A 1 189 ? 37.738 50.445 -36.338 1.00 71.75  ? 404 GLU   A OE1 1 
ATOM   1265 O OE2 . GLU   A 1 189 ? 37.326 52.157 -35.055 1.00 70.02  ? 404 GLU   A OE2 1 
ATOM   1266 N N   . ASN   A 1 190 ? 38.239 47.405 -31.211 1.00 62.10  ? 405 ASN   A N   1 
ATOM   1267 C CA  . ASN   A 1 190 ? 37.773 46.033 -31.047 1.00 65.89  ? 405 ASN   A CA  1 
ATOM   1268 C C   . ASN   A 1 190 ? 38.117 45.444 -29.674 1.00 67.92  ? 405 ASN   A C   1 
ATOM   1269 O O   . ASN   A 1 190 ? 38.025 44.228 -29.474 1.00 67.99  ? 405 ASN   A O   1 
ATOM   1270 C CB  . ASN   A 1 190 ? 38.336 45.157 -32.167 1.00 68.93  ? 405 ASN   A CB  1 
ATOM   1271 C CG  . ASN   A 1 190 ? 38.224 45.810 -33.545 1.00 67.55  ? 405 ASN   A CG  1 
ATOM   1272 O OD1 . ASN   A 1 190 ? 37.123 46.020 -34.064 1.00 67.95  ? 405 ASN   A OD1 1 
ATOM   1273 N ND2 . ASN   A 1 190 ? 39.363 46.153 -34.126 1.00 65.40  ? 405 ASN   A ND2 1 
ATOM   1274 N N   . PHE   A 1 191 ? 38.490 46.277 -28.713 1.00 63.03  ? 406 PHE   A N   1 
ATOM   1275 C CA  . PHE   A 1 191 ? 39.036 45.789 -27.454 1.00 66.35  ? 406 PHE   A CA  1 
ATOM   1276 C C   . PHE   A 1 191 ? 38.222 46.387 -26.311 1.00 67.05  ? 406 PHE   A C   1 
ATOM   1277 O O   . PHE   A 1 191 ? 38.148 47.611 -26.177 1.00 66.15  ? 406 PHE   A O   1 
ATOM   1278 C CB  . PHE   A 1 191 ? 40.522 46.156 -27.362 1.00 63.35  ? 406 PHE   A CB  1 
ATOM   1279 C CG  . PHE   A 1 191 ? 41.140 45.898 -26.029 1.00 63.51  ? 406 PHE   A CG  1 
ATOM   1280 C CD1 . PHE   A 1 191 ? 41.034 46.840 -25.005 1.00 65.16  ? 406 PHE   A CD1 1 
ATOM   1281 C CD2 . PHE   A 1 191 ? 41.847 44.744 -25.796 1.00 64.82  ? 406 PHE   A CD2 1 
ATOM   1282 C CE1 . PHE   A 1 191 ? 41.608 46.612 -23.744 1.00 64.06  ? 406 PHE   A CE1 1 
ATOM   1283 C CE2 . PHE   A 1 191 ? 42.424 44.507 -24.549 1.00 65.39  ? 406 PHE   A CE2 1 
ATOM   1284 C CZ  . PHE   A 1 191 ? 42.311 45.451 -23.531 1.00 65.47  ? 406 PHE   A CZ  1 
ATOM   1285 N N   . THR   A 1 192 ? 37.589 45.539 -25.507 1.00 64.31  ? 407 THR   A N   1 
ATOM   1286 C CA  . THR   A 1 192 ? 36.748 46.060 -24.446 1.00 72.26  ? 407 THR   A CA  1 
ATOM   1287 C C   . THR   A 1 192 ? 36.936 45.222 -23.198 1.00 71.53  ? 407 THR   A C   1 
ATOM   1288 O O   . THR   A 1 192 ? 37.332 44.065 -23.256 1.00 68.38  ? 407 THR   A O   1 
ATOM   1289 C CB  . THR   A 1 192 ? 35.272 46.085 -24.845 1.00 77.21  ? 407 THR   A CB  1 
ATOM   1290 O OG1 . THR   A 1 192 ? 34.787 44.747 -24.949 1.00 79.32  ? 407 THR   A OG1 1 
ATOM   1291 C CG2 . THR   A 1 192 ? 35.098 46.785 -26.182 1.00 76.53  ? 407 THR   A CG2 1 
ATOM   1292 N N   . ILE   A 1 193 ? 36.657 45.821 -22.054 1.00 72.16  ? 408 ILE   A N   1 
ATOM   1293 C CA  . ILE   A 1 193 ? 36.683 45.089 -20.802 1.00 71.13  ? 408 ILE   A CA  1 
ATOM   1294 C C   . ILE   A 1 193 ? 35.344 45.262 -20.117 1.00 69.81  ? 408 ILE   A C   1 
ATOM   1295 O O   . ILE   A 1 193 ? 34.724 46.325 -20.193 1.00 65.56  ? 408 ILE   A O   1 
ATOM   1296 C CB  . ILE   A 1 193 ? 37.834 45.526 -19.885 1.00 67.28  ? 408 ILE   A CB  1 
ATOM   1297 C CG1 . ILE   A 1 193 ? 39.147 45.319 -20.619 1.00 66.39  ? 408 ILE   A CG1 1 
ATOM   1298 C CG2 . ILE   A 1 193 ? 37.807 44.694 -18.581 1.00 67.20  ? 408 ILE   A CG2 1 
ATOM   1299 C CD1 . ILE   A 1 193 ? 40.356 45.534 -19.790 1.00 66.68  ? 408 ILE   A CD1 1 
ATOM   1300 N N   . LEU   A 1 194 ? 34.886 44.194 -19.477 1.00 68.38  ? 409 LEU   A N   1 
ATOM   1301 C CA  . LEU   A 1 194 ? 33.631 44.173 -18.748 1.00 69.22  ? 409 LEU   A CA  1 
ATOM   1302 C C   . LEU   A 1 194 ? 33.967 43.737 -17.338 1.00 65.81  ? 409 LEU   A C   1 
ATOM   1303 O O   . LEU   A 1 194 ? 34.605 42.700 -17.131 1.00 61.71  ? 409 LEU   A O   1 
ATOM   1304 C CB  . LEU   A 1 194 ? 32.621 43.228 -19.397 1.00 71.55  ? 409 LEU   A CB  1 
ATOM   1305 C CG  . LEU   A 1 194 ? 31.231 43.183 -18.769 1.00 70.52  ? 409 LEU   A CG  1 
ATOM   1306 C CD1 . LEU   A 1 194 ? 30.536 44.524 -18.925 1.00 69.20  ? 409 LEU   A CD1 1 
ATOM   1307 C CD2 . LEU   A 1 194 ? 30.412 42.086 -19.417 1.00 76.67  ? 409 LEU   A CD2 1 
ATOM   1308 N N   . GLN   A 1 195 ? 33.570 44.540 -16.371 1.00 63.18  ? 410 GLN   A N   1 
ATOM   1309 C CA  . GLN   A 1 195 ? 33.946 44.305 -14.994 1.00 64.21  ? 410 GLN   A CA  1 
ATOM   1310 C C   . GLN   A 1 195 ? 32.652 44.139 -14.222 1.00 64.98  ? 410 GLN   A C   1 
ATOM   1311 O O   . GLN   A 1 195 ? 31.807 45.035 -14.244 1.00 63.42  ? 410 GLN   A O   1 
ATOM   1312 C CB  . GLN   A 1 195 ? 34.751 45.482 -14.472 1.00 62.34  ? 410 GLN   A CB  1 
ATOM   1313 C CG  . GLN   A 1 195 ? 36.021 45.057 -13.838 1.00 63.90  ? 410 GLN   A CG  1 
ATOM   1314 C CD  . GLN   A 1 195 ? 36.674 46.207 -13.157 1.00 66.18  ? 410 GLN   A CD  1 
ATOM   1315 O OE1 . GLN   A 1 195 ? 35.989 47.037 -12.546 1.00 66.94  ? 410 GLN   A OE1 1 
ATOM   1316 N NE2 . GLN   A 1 195 ? 38.002 46.278 -13.240 1.00 67.66  ? 410 GLN   A NE2 1 
ATOM   1317 N N   . VAL   A 1 196 ? 32.471 42.992 -13.575 1.00 63.12  ? 411 VAL   A N   1 
ATOM   1318 C CA  . VAL   A 1 196 ? 31.228 42.694 -12.865 1.00 66.08  ? 411 VAL   A CA  1 
ATOM   1319 C C   . VAL   A 1 196 ? 31.554 42.465 -11.392 1.00 66.32  ? 411 VAL   A C   1 
ATOM   1320 O O   . VAL   A 1 196 ? 32.307 41.544 -11.056 1.00 63.08  ? 411 VAL   A O   1 
ATOM   1321 C CB  . VAL   A 1 196 ? 30.508 41.473 -13.461 1.00 66.67  ? 411 VAL   A CB  1 
ATOM   1322 C CG1 . VAL   A 1 196 ? 29.097 41.377 -12.904 1.00 67.82  ? 411 VAL   A CG1 1 
ATOM   1323 C CG2 . VAL   A 1 196 ? 30.480 41.553 -14.982 1.00 69.90  ? 411 VAL   A CG2 1 
ATOM   1324 N N   . VAL   A 1 197 ? 30.981 43.296 -10.520 1.00 66.43  ? 412 VAL   A N   1 
ATOM   1325 C CA  . VAL   A 1 197 ? 31.177 43.218 -9.073  1.00 68.63  ? 412 VAL   A CA  1 
ATOM   1326 C C   . VAL   A 1 197 ? 29.872 42.754 -8.442  1.00 67.66  ? 412 VAL   A C   1 
ATOM   1327 O O   . VAL   A 1 197 ? 28.845 43.437 -8.531  1.00 65.84  ? 412 VAL   A O   1 
ATOM   1328 C CB  . VAL   A 1 197 ? 31.620 44.567 -8.486  1.00 68.38  ? 412 VAL   A CB  1 
ATOM   1329 C CG1 . VAL   A 1 197 ? 32.075 44.401 -7.046  1.00 67.79  ? 412 VAL   A CG1 1 
ATOM   1330 C CG2 . VAL   A 1 197 ? 32.734 45.164 -9.316  1.00 67.90  ? 412 VAL   A CG2 1 
ATOM   1331 N N   . THR   A 1 198 ? 29.898 41.582 -7.839  1.00 69.03  ? 413 THR   A N   1 
ATOM   1332 C CA  . THR   A 1 198 ? 28.708 41.039 -7.222  1.00 72.25  ? 413 THR   A CA  1 
ATOM   1333 C C   . THR   A 1 198 ? 28.954 40.864 -5.735  1.00 70.64  ? 413 THR   A C   1 
ATOM   1334 O O   . THR   A 1 198 ? 30.095 40.802 -5.259  1.00 68.71  ? 413 THR   A O   1 
ATOM   1335 C CB  . THR   A 1 198 ? 28.302 39.690 -7.813  1.00 72.15  ? 413 THR   A CB  1 
ATOM   1336 O OG1 . THR   A 1 198 ? 29.344 38.741 -7.572  1.00 72.94  ? 413 THR   A OG1 1 
ATOM   1337 C CG2 . THR   A 1 198 ? 28.063 39.798 -9.281  1.00 69.29  ? 413 THR   A CG2 1 
ATOM   1338 N N   . ASN   A 1 199 ? 27.854 40.787 -5.009  1.00 74.74  ? 414 ASN   A N   1 
ATOM   1339 C CA  . ASN   A 1 199 ? 27.907 40.490 -3.591  1.00 75.62  ? 414 ASN   A CA  1 
ATOM   1340 C C   . ASN   A 1 199 ? 28.149 39.002 -3.456  1.00 75.50  ? 414 ASN   A C   1 
ATOM   1341 O O   . ASN   A 1 199 ? 27.321 38.197 -3.883  1.00 76.36  ? 414 ASN   A O   1 
ATOM   1342 C CB  . ASN   A 1 199 ? 26.602 40.923 -2.943  1.00 76.67  ? 414 ASN   A CB  1 
ATOM   1343 C CG  . ASN   A 1 199 ? 26.531 40.617 -1.475  1.00 77.96  ? 414 ASN   A CG  1 
ATOM   1344 O OD1 . ASN   A 1 199 ? 27.193 39.723 -0.951  1.00 78.65  ? 414 ASN   A OD1 1 
ATOM   1345 N ND2 . ASN   A 1 199 ? 25.778 41.446 -0.773  1.00 76.20  ? 414 ASN   A ND2 1 
ATOM   1346 N N   . ARG   A 1 200 ? 29.304 38.636 -2.913  1.00 73.97  ? 415 ARG   A N   1 
ATOM   1347 C CA  . ARG   A 1 200 ? 29.725 37.251 -3.020  1.00 77.73  ? 415 ARG   A CA  1 
ATOM   1348 C C   . ARG   A 1 200 ? 28.782 36.313 -2.290  1.00 79.51  ? 415 ARG   A C   1 
ATOM   1349 O O   . ARG   A 1 200 ? 28.676 35.138 -2.660  1.00 79.89  ? 415 ARG   A O   1 
ATOM   1350 C CB  . ARG   A 1 200 ? 31.125 37.057 -2.454  1.00 78.33  ? 415 ARG   A CB  1 
ATOM   1351 C CG  . ARG   A 1 200 ? 31.622 35.665 -2.747  1.00 77.39  ? 415 ARG   A CG  1 
ATOM   1352 C CD  . ARG   A 1 200 ? 31.518 34.817 -1.612  1.00 79.95  ? 415 ARG   A CD  1 
ATOM   1353 N NE  . ARG   A 1 200 ? 32.806 34.707 -0.947  1.00 83.60  ? 415 ARG   A NE  1 
ATOM   1354 C CZ  . ARG   A 1 200 ? 32.934 34.550 0.358   1.00 80.49  ? 415 ARG   A CZ  1 
ATOM   1355 N NH1 . ARG   A 1 200 ? 31.887 34.616 1.155   1.00 82.61  ? 415 ARG   A NH1 1 
ATOM   1356 N NH2 . ARG   A 1 200 ? 34.138 34.293 0.871   1.00 84.49  ? 415 ARG   A NH2 1 
ATOM   1357 N N   . ASP   A 1 201 ? 28.110 36.799 -1.239  1.00 77.90  ? 416 ASP   A N   1 
ATOM   1358 C CA  . ASP   A 1 201 ? 27.293 35.895 -0.447  1.00 79.07  ? 416 ASP   A CA  1 
ATOM   1359 C C   . ASP   A 1 201 ? 25.889 35.751 -1.016  1.00 80.79  ? 416 ASP   A C   1 
ATOM   1360 O O   . ASP   A 1 201 ? 25.287 34.680 -0.881  1.00 84.91  ? 416 ASP   A O   1 
ATOM   1361 C CB  . ASP   A 1 201 ? 27.233 36.348 1.017   1.00 79.78  ? 416 ASP   A CB  1 
ATOM   1362 C CG  . ASP   A 1 201 ? 28.582 36.225 1.722   1.00 80.79  ? 416 ASP   A CG  1 
ATOM   1363 O OD1 . ASP   A 1 201 ? 29.521 35.653 1.125   1.00 80.35  ? 416 ASP   A OD1 1 
ATOM   1364 O OD2 . ASP   A 1 201 ? 28.690 36.647 2.889   1.00 83.43  ? 416 ASP   A OD2 1 
ATOM   1365 N N   . THR   A 1 202 ? 25.364 36.780 -1.679  1.00 80.24  ? 417 THR   A N   1 
ATOM   1366 C CA  . THR   A 1 202 ? 23.997 36.729 -2.170  1.00 81.33  ? 417 THR   A CA  1 
ATOM   1367 C C   . THR   A 1 202 ? 23.879 36.596 -3.681  1.00 82.59  ? 417 THR   A C   1 
ATOM   1368 O O   . THR   A 1 202 ? 22.780 36.314 -4.171  1.00 84.06  ? 417 THR   A O   1 
ATOM   1369 C CB  . THR   A 1 202 ? 23.245 37.983 -1.756  1.00 79.21  ? 417 THR   A CB  1 
ATOM   1370 O OG1 . THR   A 1 202 ? 24.057 39.122 -2.062  1.00 79.36  ? 417 THR   A OG1 1 
ATOM   1371 C CG2 . THR   A 1 202 ? 23.003 37.951 -0.286  1.00 78.87  ? 417 THR   A CG2 1 
ATOM   1372 N N   . GLN   A 1 203 ? 24.953 36.813 -4.438  1.00 85.96  ? 418 GLN   A N   1 
ATOM   1373 C CA  . GLN   A 1 203 ? 24.978 36.742 -5.898  1.00 83.53  ? 418 GLN   A CA  1 
ATOM   1374 C C   . GLN   A 1 203 ? 24.371 37.985 -6.523  1.00 83.02  ? 418 GLN   A C   1 
ATOM   1375 O O   . GLN   A 1 203 ? 24.298 38.056 -7.759  1.00 83.52  ? 418 GLN   A O   1 
ATOM   1376 C CB  . GLN   A 1 203 ? 24.237 35.518 -6.451  1.00 84.86  ? 418 GLN   A CB  1 
ATOM   1377 C CG  . GLN   A 1 203 ? 24.533 34.222 -5.722  1.00 89.41  ? 418 GLN   A CG  1 
ATOM   1378 C CD  . GLN   A 1 203 ? 26.023 33.957 -5.611  1.00 92.71  ? 418 GLN   A CD  1 
ATOM   1379 O OE1 . GLN   A 1 203 ? 26.775 34.783 -5.090  1.00 91.30  ? 418 GLN   A OE1 1 
ATOM   1380 N NE2 . GLN   A 1 203 ? 26.455 32.789 -6.076  1.00 100.36 ? 418 GLN   A NE2 1 
ATOM   1381 N N   . GLU   A 1 204 ? 23.945 38.971 -5.737  1.00 77.87  ? 419 GLU   A N   1 
ATOM   1382 C CA  . GLU   A 1 204 ? 23.419 40.191 -6.333  1.00 75.67  ? 419 GLU   A CA  1 
ATOM   1383 C C   . GLU   A 1 204 ? 24.524 40.988 -7.009  1.00 71.77  ? 419 GLU   A C   1 
ATOM   1384 O O   . GLU   A 1 204 ? 25.672 41.023 -6.553  1.00 70.88  ? 419 GLU   A O   1 
ATOM   1385 C CB  . GLU   A 1 204 ? 22.714 41.064 -5.295  1.00 75.88  ? 419 GLU   A CB  1 
ATOM   1386 C CG  . GLU   A 1 204 ? 23.261 40.959 -3.897  1.00 78.72  ? 419 GLU   A CG  1 
ATOM   1387 C CD  . GLU   A 1 204 ? 22.294 41.510 -2.853  1.00 77.47  ? 419 GLU   A CD  1 
ATOM   1388 O OE1 . GLU   A 1 204 ? 21.128 41.058 -2.837  1.00 77.48  ? 419 GLU   A OE1 1 
ATOM   1389 O OE2 . GLU   A 1 204 ? 22.697 42.379 -2.049  1.00 77.84  ? 419 GLU   A OE2 1 
ATOM   1390 N N   . LEU   A 1 205 ? 24.155 41.634 -8.109  1.00 70.61  ? 420 LEU   A N   1 
ATOM   1391 C CA  . LEU   A 1 205 ? 25.071 42.481 -8.847  1.00 68.42  ? 420 LEU   A CA  1 
ATOM   1392 C C   . LEU   A 1 205 ? 25.144 43.843 -8.187  1.00 66.95  ? 420 LEU   A C   1 
ATOM   1393 O O   . LEU   A 1 205 ? 24.113 44.445 -7.878  1.00 66.42  ? 420 LEU   A O   1 
ATOM   1394 C CB  . LEU   A 1 205 ? 24.614 42.630 -10.287 1.00 66.77  ? 420 LEU   A CB  1 
ATOM   1395 C CG  . LEU   A 1 205 ? 25.529 43.627 -10.984 1.00 66.40  ? 420 LEU   A CG  1 
ATOM   1396 C CD1 . LEU   A 1 205 ? 26.679 42.842 -11.608 1.00 65.00  ? 420 LEU   A CD1 1 
ATOM   1397 C CD2 . LEU   A 1 205 ? 24.768 44.428 -12.020 1.00 67.22  ? 420 LEU   A CD2 1 
ATOM   1398 N N   . LEU   A 1 206 ? 26.359 44.317 -7.948  1.00 63.04  ? 421 LEU   A N   1 
ATOM   1399 C CA  . LEU   A 1 206 ? 26.538 45.623 -7.337  1.00 69.37  ? 421 LEU   A CA  1 
ATOM   1400 C C   . LEU   A 1 206 ? 26.928 46.682 -8.341  1.00 65.79  ? 421 LEU   A C   1 
ATOM   1401 O O   . LEU   A 1 206 ? 26.378 47.786 -8.315  1.00 63.13  ? 421 LEU   A O   1 
ATOM   1402 C CB  . LEU   A 1 206 ? 27.600 45.554 -6.242  1.00 69.82  ? 421 LEU   A CB  1 
ATOM   1403 C CG  . LEU   A 1 206 ? 27.256 44.609 -5.096  1.00 69.90  ? 421 LEU   A CG  1 
ATOM   1404 C CD1 . LEU   A 1 206 ? 28.439 44.538 -4.147  1.00 70.31  ? 421 LEU   A CD1 1 
ATOM   1405 C CD2 . LEU   A 1 206 ? 25.987 45.067 -4.372  1.00 70.07  ? 421 LEU   A CD2 1 
ATOM   1406 N N   . LEU   A 1 207 ? 27.848 46.338 -9.242  1.00 67.72  ? 422 LEU   A N   1 
ATOM   1407 C CA  . LEU   A 1 207 ? 28.488 47.271 -10.158 1.00 65.40  ? 422 LEU   A CA  1 
ATOM   1408 C C   . LEU   A 1 207 ? 28.853 46.522 -11.425 1.00 64.04  ? 422 LEU   A C   1 
ATOM   1409 O O   . LEU   A 1 207 ? 29.543 45.505 -11.350 1.00 61.88  ? 422 LEU   A O   1 
ATOM   1410 C CB  . LEU   A 1 207 ? 29.760 47.847 -9.551  1.00 62.42  ? 422 LEU   A CB  1 
ATOM   1411 C CG  . LEU   A 1 207 ? 29.647 49.279 -9.115  1.00 64.13  ? 422 LEU   A CG  1 
ATOM   1412 C CD1 . LEU   A 1 207 ? 31.053 49.862 -9.011  1.00 65.42  ? 422 LEU   A CD1 1 
ATOM   1413 C CD2 . LEU   A 1 207 ? 28.768 49.995 -10.117 1.00 66.01  ? 422 LEU   A CD2 1 
ATOM   1414 N N   . CYS   A 1 208 ? 28.417 47.028 -12.574 1.00 64.07  ? 423 CYS   A N   1 
ATOM   1415 C CA  . CYS   A 1 208 ? 28.840 46.512 -13.875 1.00 63.73  ? 423 CYS   A CA  1 
ATOM   1416 C C   . CYS   A 1 208 ? 29.374 47.684 -14.689 1.00 62.86  ? 423 CYS   A C   1 
ATOM   1417 O O   . CYS   A 1 208 ? 28.606 48.570 -15.075 1.00 64.10  ? 423 CYS   A O   1 
ATOM   1418 C CB  . CYS   A 1 208 ? 27.693 45.808 -14.594 1.00 64.79  ? 423 CYS   A CB  1 
ATOM   1419 S SG  . CYS   A 1 208 ? 28.172 45.123 -16.226 1.00 60.59  ? 423 CYS   A SG  1 
ATOM   1420 N N   . THR   A 1 209 ? 30.692 47.711 -14.902 1.00 59.68  ? 424 THR   A N   1 
ATOM   1421 C CA  . THR   A 1 209 ? 31.357 48.742 -15.696 1.00 63.74  ? 424 THR   A CA  1 
ATOM   1422 C C   . THR   A 1 209 ? 31.885 48.149 -16.991 1.00 62.67  ? 424 THR   A C   1 
ATOM   1423 O O   . THR   A 1 209 ? 32.648 47.174 -16.973 1.00 58.15  ? 424 THR   A O   1 
ATOM   1424 C CB  . THR   A 1 209 ? 32.531 49.385 -14.958 1.00 63.90  ? 424 THR   A CB  1 
ATOM   1425 O OG1 . THR   A 1 209 ? 32.104 49.843 -13.673 1.00 66.72  ? 424 THR   A OG1 1 
ATOM   1426 C CG2 . THR   A 1 209 ? 33.035 50.578 -15.729 1.00 63.15  ? 424 THR   A CG2 1 
ATOM   1427 N N   . ALA   A 1 210 ? 31.512 48.774 -18.096 1.00 66.15  ? 425 ALA   A N   1 
ATOM   1428 C CA  . ALA   A 1 210 ? 32.049 48.479 -19.415 1.00 64.03  ? 425 ALA   A CA  1 
ATOM   1429 C C   . ALA   A 1 210 ? 33.121 49.499 -19.766 1.00 63.18  ? 425 ALA   A C   1 
ATOM   1430 O O   . ALA   A 1 210 ? 32.883 50.705 -19.657 1.00 64.40  ? 425 ALA   A O   1 
ATOM   1431 C CB  . ALA   A 1 210 ? 30.935 48.524 -20.456 1.00 65.82  ? 425 ALA   A CB  1 
ATOM   1432 N N   . TYR   A 1 211 ? 34.303 49.023 -20.144 1.00 60.00  ? 426 TYR   A N   1 
ATOM   1433 C CA  . TYR   A 1 211 ? 35.393 49.884 -20.591 1.00 61.98  ? 426 TYR   A CA  1 
ATOM   1434 C C   . TYR   A 1 211 ? 35.543 49.808 -22.108 1.00 64.83  ? 426 TYR   A C   1 
ATOM   1435 O O   . TYR   A 1 211 ? 35.462 48.722 -22.688 1.00 63.81  ? 426 TYR   A O   1 
ATOM   1436 C CB  . TYR   A 1 211 ? 36.711 49.487 -19.935 1.00 60.30  ? 426 TYR   A CB  1 
ATOM   1437 C CG  . TYR   A 1 211 ? 36.640 49.582 -18.438 1.00 62.32  ? 426 TYR   A CG  1 
ATOM   1438 C CD1 . TYR   A 1 211 ? 36.943 50.765 -17.776 1.00 62.13  ? 426 TYR   A CD1 1 
ATOM   1439 C CD2 . TYR   A 1 211 ? 36.233 48.500 -17.692 1.00 63.10  ? 426 TYR   A CD2 1 
ATOM   1440 C CE1 . TYR   A 1 211 ? 36.864 50.839 -16.392 1.00 64.16  ? 426 TYR   A CE1 1 
ATOM   1441 C CE2 . TYR   A 1 211 ? 36.145 48.562 -16.330 1.00 64.44  ? 426 TYR   A CE2 1 
ATOM   1442 C CZ  . TYR   A 1 211 ? 36.456 49.728 -15.681 1.00 65.17  ? 426 TYR   A CZ  1 
ATOM   1443 O OH  . TYR   A 1 211 ? 36.364 49.761 -14.315 1.00 64.30  ? 426 TYR   A OH  1 
ATOM   1444 N N   . VAL   A 1 212 ? 35.752 50.979 -22.737 1.00 60.05  ? 427 VAL   A N   1 
ATOM   1445 C CA  . VAL   A 1 212 ? 36.138 51.136 -24.140 1.00 62.80  ? 427 VAL   A CA  1 
ATOM   1446 C C   . VAL   A 1 212 ? 37.304 52.115 -24.191 1.00 61.50  ? 427 VAL   A C   1 
ATOM   1447 O O   . VAL   A 1 212 ? 37.443 52.969 -23.308 1.00 58.78  ? 427 VAL   A O   1 
ATOM   1448 C CB  . VAL   A 1 212 ? 34.979 51.642 -25.023 1.00 62.94  ? 427 VAL   A CB  1 
ATOM   1449 C CG1 . VAL   A 1 212 ? 33.795 50.697 -24.967 1.00 65.76  ? 427 VAL   A CG1 1 
ATOM   1450 C CG2 . VAL   A 1 212 ? 34.574 53.005 -24.590 1.00 62.51  ? 427 VAL   A CG2 1 
ATOM   1451 N N   . PHE   A 1 213 ? 38.124 52.021 -25.247 1.00 60.13  ? 428 PHE   A N   1 
ATOM   1452 C CA  . PHE   A 1 213 ? 39.471 52.590 -25.237 1.00 60.00  ? 428 PHE   A CA  1 
ATOM   1453 C C   . PHE   A 1 213 ? 39.834 53.330 -26.518 1.00 59.05  ? 428 PHE   A C   1 
ATOM   1454 O O   . PHE   A 1 213 ? 39.392 52.979 -27.617 1.00 56.35  ? 428 PHE   A O   1 
ATOM   1455 C CB  . PHE   A 1 213 ? 40.526 51.510 -25.024 1.00 61.46  ? 428 PHE   A CB  1 
ATOM   1456 C CG  . PHE   A 1 213 ? 40.383 50.776 -23.735 1.00 61.09  ? 428 PHE   A CG  1 
ATOM   1457 C CD1 . PHE   A 1 213 ? 39.514 49.696 -23.631 1.00 61.78  ? 428 PHE   A CD1 1 
ATOM   1458 C CD2 . PHE   A 1 213 ? 41.113 51.159 -22.614 1.00 60.53  ? 428 PHE   A CD2 1 
ATOM   1459 C CE1 . PHE   A 1 213 ? 39.375 49.010 -22.426 1.00 62.17  ? 428 PHE   A CE1 1 
ATOM   1460 C CE2 . PHE   A 1 213 ? 40.971 50.479 -21.415 1.00 59.74  ? 428 PHE   A CE2 1 
ATOM   1461 C CZ  . PHE   A 1 213 ? 40.109 49.405 -21.325 1.00 59.32  ? 428 PHE   A CZ  1 
ATOM   1462 N N   . GLU   A 1 214 ? 40.639 54.376 -26.340 1.00 61.54  ? 429 GLU   A N   1 
ATOM   1463 C CA  . GLU   A 1 214 ? 41.412 55.065 -27.366 1.00 60.51  ? 429 GLU   A CA  1 
ATOM   1464 C C   . GLU   A 1 214 ? 42.727 55.433 -26.705 1.00 62.29  ? 429 GLU   A C   1 
ATOM   1465 O O   . GLU   A 1 214 ? 42.952 55.113 -25.533 1.00 62.99  ? 429 GLU   A O   1 
ATOM   1466 C CB  . GLU   A 1 214 ? 40.723 56.326 -27.901 1.00 58.78  ? 429 GLU   A CB  1 
ATOM   1467 C CG  . GLU   A 1 214 ? 39.426 56.054 -28.610 1.00 60.22  ? 429 GLU   A CG  1 
ATOM   1468 C CD  . GLU   A 1 214 ? 38.916 57.240 -29.393 1.00 63.42  ? 429 GLU   A CD  1 
ATOM   1469 O OE1 . GLU   A 1 214 ? 39.548 58.325 -29.373 1.00 63.18  ? 429 GLU   A OE1 1 
ATOM   1470 O OE2 . GLU   A 1 214 ? 37.866 57.074 -30.048 1.00 65.09  ? 429 GLU   A OE2 1 
ATOM   1471 N N   . VAL   A 1 215 ? 43.592 56.131 -27.424 1.00 54.33  ? 430 VAL   A N   1 
ATOM   1472 C CA  . VAL   A 1 215 ? 44.856 56.562 -26.850 1.00 62.21  ? 430 VAL   A CA  1 
ATOM   1473 C C   . VAL   A 1 215 ? 44.849 58.081 -26.762 1.00 66.29  ? 430 VAL   A C   1 
ATOM   1474 O O   . VAL   A 1 215 ? 44.199 58.771 -27.558 1.00 63.12  ? 430 VAL   A O   1 
ATOM   1475 C CB  . VAL   A 1 215 ? 46.081 56.084 -27.644 1.00 63.45  ? 430 VAL   A CB  1 
ATOM   1476 C CG1 . VAL   A 1 215 ? 46.100 54.548 -27.742 1.00 60.00  ? 430 VAL   A CG1 1 
ATOM   1477 C CG2 . VAL   A 1 215 ? 46.091 56.786 -29.034 1.00 62.21  ? 430 VAL   A CG2 1 
ATOM   1478 N N   . SER   A 1 216 ? 45.555 58.599 -25.763 1.00 68.33  ? 431 SER   A N   1 
ATOM   1479 C CA  . SER   A 1 216 ? 45.776 60.026 -25.635 1.00 70.80  ? 431 SER   A CA  1 
ATOM   1480 C C   . SER   A 1 216 ? 47.225 60.340 -25.989 1.00 72.97  ? 431 SER   A C   1 
ATOM   1481 O O   . SER   A 1 216 ? 48.096 59.463 -26.002 1.00 73.06  ? 431 SER   A O   1 
ATOM   1482 C CB  . SER   A 1 216 ? 45.458 60.512 -24.219 1.00 70.18  ? 431 SER   A CB  1 
ATOM   1483 O OG  . SER   A 1 216 ? 45.843 61.869 -24.063 1.00 69.57  ? 431 SER   A OG  1 
ATOM   1484 N N   . THR   A 1 217 ? 47.486 61.603 -26.301 1.00 76.03  ? 432 THR   A N   1 
ATOM   1485 C CA  . THR   A 1 217 ? 48.868 61.987 -26.506 1.00 80.07  ? 432 THR   A CA  1 
ATOM   1486 C C   . THR   A 1 217 ? 49.578 62.017 -25.157 1.00 83.59  ? 432 THR   A C   1 
ATOM   1487 O O   . THR   A 1 217 ? 48.989 61.758 -24.107 1.00 81.84  ? 432 THR   A O   1 
ATOM   1488 C CB  . THR   A 1 217 ? 48.930 63.320 -27.231 1.00 80.89  ? 432 THR   A CB  1 
ATOM   1489 O OG1 . THR   A 1 217 ? 48.496 64.343 -26.325 1.00 81.70  ? 432 THR   A OG1 1 
ATOM   1490 C CG2 . THR   A 1 217 ? 48.030 63.286 -28.483 1.00 76.26  ? 432 THR   A CG2 1 
ATOM   1491 N N   . SER   A 1 218 ? 50.866 62.331 -25.174 1.00 95.98  ? 433 SER   A N   1 
ATOM   1492 C CA  . SER   A 1 218 ? 51.606 62.380 -23.917 1.00 93.43  ? 433 SER   A CA  1 
ATOM   1493 C C   . SER   A 1 218 ? 51.430 63.714 -23.191 1.00 93.27  ? 433 SER   A C   1 
ATOM   1494 O O   . SER   A 1 218 ? 51.415 63.737 -21.952 1.00 90.57  ? 433 SER   A O   1 
ATOM   1495 C CB  . SER   A 1 218 ? 53.085 62.086 -24.186 1.00 96.63  ? 433 SER   A CB  1 
ATOM   1496 O OG  . SER   A 1 218 ? 53.325 62.045 -25.585 1.00 98.72  ? 433 SER   A OG  1 
ATOM   1497 N N   . GLU   A 1 219 ? 51.290 64.832 -23.926 1.00 85.67  ? 434 GLU   A N   1 
ATOM   1498 C CA  . GLU   A 1 219 ? 51.047 66.121 -23.277 1.00 84.81  ? 434 GLU   A CA  1 
ATOM   1499 C C   . GLU   A 1 219 ? 49.610 66.268 -22.782 1.00 83.74  ? 434 GLU   A C   1 
ATOM   1500 O O   . GLU   A 1 219 ? 49.364 67.051 -21.855 1.00 82.42  ? 434 GLU   A O   1 
ATOM   1501 C CB  . GLU   A 1 219 ? 51.386 67.297 -24.212 1.00 86.94  ? 434 GLU   A CB  1 
ATOM   1502 C CG  . GLU   A 1 219 ? 50.579 67.405 -25.522 1.00 89.34  ? 434 GLU   A CG  1 
ATOM   1503 C CD  . GLU   A 1 219 ? 50.844 68.730 -26.284 1.00 93.07  ? 434 GLU   A CD  1 
ATOM   1504 O OE1 . GLU   A 1 219 ? 51.388 69.695 -25.701 1.00 91.66  ? 434 GLU   A OE1 1 
ATOM   1505 O OE2 . GLU   A 1 219 ? 50.544 68.787 -27.497 1.00 93.24  ? 434 GLU   A OE2 1 
ATOM   1506 N N   . ARG   A 1 220 ? 48.653 65.546 -23.376 1.00 76.92  ? 435 ARG   A N   1 
ATOM   1507 C CA  . ARG   A 1 220 ? 47.286 65.578 -22.868 1.00 75.79  ? 435 ARG   A CA  1 
ATOM   1508 C C   . ARG   A 1 220 ? 47.109 64.668 -21.660 1.00 73.96  ? 435 ARG   A C   1 
ATOM   1509 O O   . ARG   A 1 220 ? 46.337 65.008 -20.756 1.00 74.07  ? 435 ARG   A O   1 
ATOM   1510 C CB  . ARG   A 1 220 ? 46.281 65.184 -23.962 1.00 72.48  ? 435 ARG   A CB  1 
ATOM   1511 C CG  . ARG   A 1 220 ? 45.855 66.339 -24.878 1.00 70.28  ? 435 ARG   A CG  1 
ATOM   1512 C CD  . ARG   A 1 220 ? 44.446 66.152 -25.452 1.00 69.14  ? 435 ARG   A CD  1 
ATOM   1513 N NE  . ARG   A 1 220 ? 43.429 66.365 -24.426 1.00 71.92  ? 435 ARG   A NE  1 
ATOM   1514 C CZ  . ARG   A 1 220 ? 42.173 66.729 -24.659 1.00 70.32  ? 435 ARG   A CZ  1 
ATOM   1515 N NH1 . ARG   A 1 220 ? 41.748 67.017 -25.886 1.00 70.28  ? 435 ARG   A NH1 1 
ATOM   1516 N NH2 . ARG   A 1 220 ? 41.319 66.784 -23.641 1.00 66.53  ? 435 ARG   A NH2 1 
ATOM   1517 N N   . GLY   A 1 221 ? 47.820 63.544 -21.600 1.00 75.35  ? 436 GLY   A N   1 
ATOM   1518 C CA  . GLY   A 1 221 ? 47.745 62.677 -20.451 1.00 73.30  ? 436 GLY   A CA  1 
ATOM   1519 C C   . GLY   A 1 221 ? 46.484 61.852 -20.472 1.00 69.24  ? 436 GLY   A C   1 
ATOM   1520 O O   . GLY   A 1 221 ? 45.533 62.109 -21.217 1.00 66.90  ? 436 GLY   A O   1 
ATOM   1521 N N   . ALA   A 1 222 ? 46.492 60.810 -19.637 1.00 68.55  ? 437 ALA   A N   1 
ATOM   1522 C CA  . ALA   A 1 222 ? 45.351 59.904 -19.561 1.00 67.63  ? 437 ALA   A CA  1 
ATOM   1523 C C   . ALA   A 1 222 ? 44.092 60.650 -19.131 1.00 63.68  ? 437 ALA   A C   1 
ATOM   1524 O O   . ALA   A 1 222 ? 44.150 61.608 -18.366 1.00 64.35  ? 437 ALA   A O   1 
ATOM   1525 C CB  . ALA   A 1 222 ? 45.632 58.761 -18.583 1.00 65.52  ? 437 ALA   A CB  1 
ATOM   1526 N N   . GLN   A 1 223 ? 42.945 60.221 -19.655 1.00 61.89  ? 438 GLN   A N   1 
ATOM   1527 C CA  . GLN   A 1 223 ? 41.680 60.893 -19.404 1.00 64.75  ? 438 GLN   A CA  1 
ATOM   1528 C C   . GLN   A 1 223 ? 40.576 59.852 -19.478 1.00 66.66  ? 438 GLN   A C   1 
ATOM   1529 O O   . GLN   A 1 223 ? 40.756 58.771 -20.036 1.00 65.03  ? 438 GLN   A O   1 
ATOM   1530 C CB  . GLN   A 1 223 ? 41.385 62.012 -20.419 1.00 66.21  ? 438 GLN   A CB  1 
ATOM   1531 C CG  . GLN   A 1 223 ? 40.273 62.952 -19.976 1.00 67.58  ? 438 GLN   A CG  1 
ATOM   1532 C CD  . GLN   A 1 223 ? 39.800 63.915 -21.059 1.00 70.64  ? 438 GLN   A CD  1 
ATOM   1533 O OE1 . GLN   A 1 223 ? 38.856 64.705 -20.856 1.00 70.78  ? 438 GLN   A OE1 1 
ATOM   1534 N NE2 . GLN   A 1 223 ? 40.432 63.844 -22.224 1.00 68.98  ? 438 GLN   A NE2 1 
ATOM   1535 N N   . HIS   A 1 224 ? 39.417 60.191 -18.920 1.00 63.23  ? 439 HIS   A N   1 
ATOM   1536 C CA  . HIS   A 1 224 ? 38.292 59.276 -18.972 1.00 67.38  ? 439 HIS   A CA  1 
ATOM   1537 C C   . HIS   A 1 224 ? 37.004 60.077 -18.910 1.00 69.70  ? 439 HIS   A C   1 
ATOM   1538 O O   . HIS   A 1 224 ? 36.990 61.234 -18.503 1.00 68.70  ? 439 HIS   A O   1 
ATOM   1539 C CB  . HIS   A 1 224 ? 38.369 58.275 -17.820 1.00 65.96  ? 439 HIS   A CB  1 
ATOM   1540 C CG  . HIS   A 1 224 ? 38.409 58.944 -16.488 1.00 68.18  ? 439 HIS   A CG  1 
ATOM   1541 N ND1 . HIS   A 1 224 ? 37.267 59.237 -15.777 1.00 66.20  ? 439 HIS   A ND1 1 
ATOM   1542 C CD2 . HIS   A 1 224 ? 39.444 59.436 -15.768 1.00 65.94  ? 439 HIS   A CD2 1 
ATOM   1543 C CE1 . HIS   A 1 224 ? 37.598 59.865 -14.664 1.00 67.85  ? 439 HIS   A CE1 1 
ATOM   1544 N NE2 . HIS   A 1 224 ? 38.913 60.006 -14.641 1.00 67.10  ? 439 HIS   A NE2 1 
ATOM   1545 N N   A HIS   A 1 225 ? 35.915 59.460 -19.345 0.45 67.10  ? 440 HIS   A N   1 
ATOM   1546 N N   B HIS   A 1 225 ? 35.918 59.427 -19.320 0.55 71.28  ? 440 HIS   A N   1 
ATOM   1547 C CA  A HIS   A 1 225 ? 34.604 60.052 -19.132 0.45 69.73  ? 440 HIS   A CA  1 
ATOM   1548 C CA  B HIS   A 1 225 ? 34.569 59.989 -19.278 0.55 71.42  ? 440 HIS   A CA  1 
ATOM   1549 C C   A HIS   A 1 225 ? 33.645 58.932 -18.777 0.45 67.78  ? 440 HIS   A C   1 
ATOM   1550 C C   B HIS   A 1 225 ? 33.655 58.873 -18.785 0.55 68.90  ? 440 HIS   A C   1 
ATOM   1551 O O   A HIS   A 1 225 ? 33.487 57.973 -19.539 0.45 67.51  ? 440 HIS   A O   1 
ATOM   1552 O O   B HIS   A 1 225 ? 33.527 57.843 -19.455 0.55 70.06  ? 440 HIS   A O   1 
ATOM   1553 C CB  A HIS   A 1 225 ? 34.135 60.852 -20.351 0.45 72.84  ? 440 HIS   A CB  1 
ATOM   1554 C CB  B HIS   A 1 225 ? 34.149 60.490 -20.665 0.55 72.92  ? 440 HIS   A CB  1 
ATOM   1555 C CG  A HIS   A 1 225 ? 34.556 62.288 -20.306 0.45 74.33  ? 440 HIS   A CG  1 
ATOM   1556 C CG  B HIS   A 1 225 ? 32.950 61.391 -20.674 0.55 73.99  ? 440 HIS   A CG  1 
ATOM   1557 N ND1 A HIS   A 1 225 ? 35.879 62.670 -20.342 0.45 73.11  ? 440 HIS   A ND1 1 
ATOM   1558 N ND1 B HIS   A 1 225 ? 32.737 62.324 -21.667 0.55 75.59  ? 440 HIS   A ND1 1 
ATOM   1559 C CD2 A HIS   A 1 225 ? 33.838 63.430 -20.191 0.45 74.16  ? 440 HIS   A CD2 1 
ATOM   1560 C CD2 B HIS   A 1 225 ? 31.884 61.481 -19.843 0.55 74.59  ? 440 HIS   A CD2 1 
ATOM   1561 C CE1 A HIS   A 1 225 ? 35.958 63.985 -20.264 0.45 72.73  ? 440 HIS   A CE1 1 
ATOM   1562 C CE1 B HIS   A 1 225 ? 31.608 62.968 -21.434 0.55 76.85  ? 440 HIS   A CE1 1 
ATOM   1563 N NE2 A HIS   A 1 225 ? 34.733 64.471 -20.172 0.45 72.68  ? 440 HIS   A NE2 1 
ATOM   1564 N NE2 B HIS   A 1 225 ? 31.068 62.474 -20.335 0.55 77.03  ? 440 HIS   A NE2 1 
ATOM   1565 N N   . ILE   A 1 226 ? 33.028 59.057 -17.619 1.00 72.63  ? 441 ILE   A N   1 
ATOM   1566 C CA  . ILE   A 1 226 ? 32.163 58.027 -17.040 1.00 71.25  ? 441 ILE   A CA  1 
ATOM   1567 C C   . ILE   A 1 226 ? 30.723 58.280 -17.460 1.00 71.06  ? 441 ILE   A C   1 
ATOM   1568 O O   . ILE   A 1 226 ? 30.236 59.411 -17.401 1.00 72.77  ? 441 ILE   A O   1 
ATOM   1569 C CB  . ILE   A 1 226 ? 32.308 58.013 -15.501 1.00 69.31  ? 441 ILE   A CB  1 
ATOM   1570 C CG1 . ILE   A 1 226 ? 33.767 57.750 -15.118 1.00 66.97  ? 441 ILE   A CG1 1 
ATOM   1571 C CG2 . ILE   A 1 226 ? 31.317 57.066 -14.845 1.00 68.47  ? 441 ILE   A CG2 1 
ATOM   1572 C CD1 . ILE   A 1 226 ? 34.011 57.792 -13.635 1.00 66.59  ? 441 ILE   A CD1 1 
ATOM   1573 N N   . TYR   A 1 227 ? 30.018 57.223 -17.857 1.00 70.45  ? 442 TYR   A N   1 
ATOM   1574 C CA  . TYR   A 1 227 ? 28.628 57.375 -18.270 1.00 69.90  ? 442 TYR   A CA  1 
ATOM   1575 C C   . TYR   A 1 227 ? 27.739 56.380 -17.536 1.00 70.48  ? 442 TYR   A C   1 
ATOM   1576 O O   . TYR   A 1 227 ? 28.192 55.322 -17.099 1.00 69.83  ? 442 TYR   A O   1 
ATOM   1577 C CB  . TYR   A 1 227 ? 28.475 57.156 -19.778 1.00 71.57  ? 442 TYR   A CB  1 
ATOM   1578 C CG  . TYR   A 1 227 ? 29.295 58.057 -20.670 1.00 70.97  ? 442 TYR   A CG  1 
ATOM   1579 C CD1 . TYR   A 1 227 ? 30.613 57.742 -20.997 1.00 70.44  ? 442 TYR   A CD1 1 
ATOM   1580 C CD2 . TYR   A 1 227 ? 28.732 59.173 -21.249 1.00 74.20  ? 442 TYR   A CD2 1 
ATOM   1581 C CE1 . TYR   A 1 227 ? 31.355 58.562 -21.849 1.00 70.45  ? 442 TYR   A CE1 1 
ATOM   1582 C CE2 . TYR   A 1 227 ? 29.459 59.980 -22.097 1.00 74.48  ? 442 TYR   A CE2 1 
ATOM   1583 C CZ  . TYR   A 1 227 ? 30.765 59.678 -22.401 1.00 70.78  ? 442 TYR   A CZ  1 
ATOM   1584 O OH  . TYR   A 1 227 ? 31.460 60.522 -23.255 1.00 71.55  ? 442 TYR   A OH  1 
ATOM   1585 N N   . ARG   A 1 228 ? 26.456 56.716 -17.427 1.00 71.90  ? 443 ARG   A N   1 
ATOM   1586 C CA  . ARG   A 1 228 ? 25.445 55.760 -16.994 1.00 73.10  ? 443 ARG   A CA  1 
ATOM   1587 C C   . ARG   A 1 228 ? 24.840 55.067 -18.209 1.00 74.15  ? 443 ARG   A C   1 
ATOM   1588 O O   . ARG   A 1 228 ? 24.577 55.705 -19.229 1.00 74.98  ? 443 ARG   A O   1 
ATOM   1589 C CB  . ARG   A 1 228 ? 24.337 56.444 -16.183 1.00 76.30  ? 443 ARG   A CB  1 
ATOM   1590 C CG  . ARG   A 1 228 ? 24.819 57.237 -14.968 1.00 78.92  ? 443 ARG   A CG  1 
ATOM   1591 C CD  . ARG   A 1 228 ? 23.677 57.944 -14.209 1.00 84.33  ? 443 ARG   A CD  1 
ATOM   1592 N NE  . ARG   A 1 228 ? 22.381 57.875 -14.879 1.00 85.97  ? 443 ARG   A NE  1 
ATOM   1593 C CZ  . ARG   A 1 228 ? 21.936 58.770 -15.754 1.00 87.33  ? 443 ARG   A CZ  1 
ATOM   1594 N NH1 . ARG   A 1 228 ? 22.680 59.803 -16.129 1.00 88.30  ? 443 ARG   A NH1 1 
ATOM   1595 N NH2 . ARG   A 1 228 ? 20.708 58.635 -16.255 1.00 90.09  ? 443 ARG   A NH2 1 
ATOM   1596 N N   . LEU   A 1 229 ? 24.605 53.761 -18.096 1.00 73.21  ? 444 LEU   A N   1 
ATOM   1597 C CA  . LEU   A 1 229 ? 23.996 53.020 -19.194 1.00 76.31  ? 444 LEU   A CA  1 
ATOM   1598 C C   . LEU   A 1 229 ? 22.492 52.923 -18.979 1.00 79.85  ? 444 LEU   A C   1 
ATOM   1599 O O   . LEU   A 1 229 ? 22.033 52.539 -17.898 1.00 80.41  ? 444 LEU   A O   1 
ATOM   1600 C CB  . LEU   A 1 229 ? 24.613 51.624 -19.338 1.00 75.60  ? 444 LEU   A CB  1 
ATOM   1601 C CG  . LEU   A 1 229 ? 26.016 51.476 -19.957 1.00 72.71  ? 444 LEU   A CG  1 
ATOM   1602 C CD1 . LEU   A 1 229 ? 26.528 50.064 -19.753 1.00 70.61  ? 444 LEU   A CD1 1 
ATOM   1603 C CD2 . LEU   A 1 229 ? 26.063 51.829 -21.439 1.00 76.14  ? 444 LEU   A CD2 1 
ATOM   1604 N N   . VAL   A 1 230 ? 21.728 53.274 -20.005 1.00 85.41  ? 445 VAL   A N   1 
ATOM   1605 C CA  . VAL   A 1 230 ? 20.281 53.259 -19.951 1.00 90.79  ? 445 VAL   A CA  1 
ATOM   1606 C C   . VAL   A 1 230 ? 19.777 52.470 -21.151 1.00 94.66  ? 445 VAL   A C   1 
ATOM   1607 O O   . VAL   A 1 230 ? 20.554 52.044 -22.000 1.00 95.40  ? 445 VAL   A O   1 
ATOM   1608 C CB  . VAL   A 1 230 ? 19.689 54.681 -19.931 1.00 90.88  ? 445 VAL   A CB  1 
ATOM   1609 C CG1 . VAL   A 1 230 ? 20.339 55.498 -18.832 1.00 87.17  ? 445 VAL   A CG1 1 
ATOM   1610 C CG2 . VAL   A 1 230 ? 19.876 55.352 -21.281 1.00 92.49  ? 445 VAL   A CG2 1 
ATOM   1611 N N   . ARG   A 1 231 ? 18.462 52.276 -21.216 1.00 95.08  ? 446 ARG   A N   1 
ATOM   1612 C CA  . ARG   A 1 231 ? 17.877 51.569 -22.350 1.00 98.82  ? 446 ARG   A CA  1 
ATOM   1613 C C   . ARG   A 1 231 ? 16.629 52.302 -22.830 1.00 104.78 ? 446 ARG   A C   1 
ATOM   1614 O O   . ARG   A 1 231 ? 16.465 52.544 -24.032 1.00 106.06 ? 446 ARG   A O   1 
ATOM   1615 C CB  . ARG   A 1 231 ? 17.568 50.119 -21.967 1.00 98.92  ? 446 ARG   A CB  1 
ATOM   1616 C CG  . ARG   A 1 231 ? 17.795 49.102 -23.072 1.00 99.37  ? 446 ARG   A CG  1 
ATOM   1617 C CD  . ARG   A 1 231 ? 17.796 47.683 -22.513 1.00 100.97 ? 446 ARG   A CD  1 
ATOM   1618 N NE  . ARG   A 1 231 ? 16.521 47.016 -22.735 1.00 106.62 ? 446 ARG   A NE  1 
ATOM   1619 C CZ  . ARG   A 1 231 ? 15.502 47.047 -21.886 1.00 110.62 ? 446 ARG   A CZ  1 
ATOM   1620 N NH1 . ARG   A 1 231 ? 15.591 47.668 -20.719 1.00 107.84 ? 446 ARG   A NH1 1 
ATOM   1621 N NH2 . ARG   A 1 231 ? 14.355 46.459 -22.223 1.00 112.54 ? 446 ARG   A NH2 1 
ATOM   1622 N N   . ASP   A 1 232 ? 15.758 52.689 -21.900 1.00 113.85 ? 447 ASP   A N   1 
ATOM   1623 C CA  . ASP   A 1 232 ? 14.575 53.482 -22.242 1.00 116.70 ? 447 ASP   A CA  1 
ATOM   1624 C C   . ASP   A 1 232 ? 14.951 54.709 -23.045 1.00 114.60 ? 447 ASP   A C   1 
ATOM   1625 O O   . ASP   A 1 232 ? 14.599 54.848 -24.220 1.00 113.24 ? 447 ASP   A O   1 
ATOM   1626 C CB  . ASP   A 1 232 ? 13.816 53.920 -20.978 1.00 118.23 ? 447 ASP   A CB  1 
ATOM   1627 C CG  . ASP   A 1 232 ? 13.135 52.769 -20.270 1.00 120.60 ? 447 ASP   A CG  1 
ATOM   1628 O OD1 . ASP   A 1 232 ? 12.698 51.827 -20.960 1.00 123.41 ? 447 ASP   A OD1 1 
ATOM   1629 O OD2 . ASP   A 1 232 ? 13.040 52.805 -19.024 1.00 122.44 ? 447 ASP   A OD2 1 
ATOM   1630 N N   . ALA   B 1 5   ? 58.862 12.363 -8.456  1.00 91.52  ? 220 ALA   B N   1 
ATOM   1631 C CA  . ALA   B 1 5   ? 57.421 12.597 -8.574  1.00 91.96  ? 220 ALA   B CA  1 
ATOM   1632 C C   . ALA   B 1 5   ? 56.658 11.299 -8.841  1.00 94.17  ? 220 ALA   B C   1 
ATOM   1633 O O   . ALA   B 1 5   ? 56.942 10.587 -9.809  1.00 94.28  ? 220 ALA   B O   1 
ATOM   1634 C CB  . ALA   B 1 5   ? 57.133 13.612 -9.672  1.00 84.65  ? 220 ALA   B CB  1 
ATOM   1635 N N   . ARG   B 1 6   ? 55.679 11.009 -7.976  1.00 101.69 ? 221 ARG   B N   1 
ATOM   1636 C CA  . ARG   B 1 6   ? 54.883 9.791  -8.052  1.00 101.22 ? 221 ARG   B CA  1 
ATOM   1637 C C   . ARG   B 1 6   ? 53.420 10.043 -8.408  1.00 98.72  ? 221 ARG   B C   1 
ATOM   1638 O O   . ARG   B 1 6   ? 52.671 9.078  -8.593  1.00 100.46 ? 221 ARG   B O   1 
ATOM   1639 C CB  . ARG   B 1 6   ? 54.955 9.035  -6.717  1.00 103.96 ? 221 ARG   B CB  1 
ATOM   1640 C CG  . ARG   B 1 6   ? 56.314 8.410  -6.421  1.00 108.47 ? 221 ARG   B CG  1 
ATOM   1641 C CD  . ARG   B 1 6   ? 56.478 7.131  -7.205  1.00 111.86 ? 221 ARG   B CD  1 
ATOM   1642 N NE  . ARG   B 1 6   ? 57.264 6.100  -6.531  1.00 118.85 ? 221 ARG   B NE  1 
ATOM   1643 C CZ  . ARG   B 1 6   ? 58.474 6.265  -6.010  1.00 117.42 ? 221 ARG   B CZ  1 
ATOM   1644 N NH1 . ARG   B 1 6   ? 59.101 7.429  -6.064  1.00 116.21 ? 221 ARG   B NH1 1 
ATOM   1645 N NH2 . ARG   B 1 6   ? 59.075 5.229  -5.429  1.00 117.64 ? 221 ARG   B NH2 1 
ATOM   1646 N N   . GLY   B 1 7   ? 52.991 11.301 -8.484  1.00 93.53  ? 222 GLY   B N   1 
ATOM   1647 C CA  . GLY   B 1 7   ? 51.670 11.655 -8.971  1.00 84.80  ? 222 GLY   B CA  1 
ATOM   1648 C C   . GLY   B 1 7   ? 51.721 13.033 -9.594  1.00 78.00  ? 222 GLY   B C   1 
ATOM   1649 O O   . GLY   B 1 7   ? 52.813 13.575 -9.775  1.00 79.14  ? 222 GLY   B O   1 
ATOM   1650 N N   . LEU   B 1 8   ? 50.584 13.625 -9.929  1.00 73.19  ? 223 LEU   B N   1 
ATOM   1651 C CA  . LEU   B 1 8   ? 50.588 15.021 -10.360 1.00 72.57  ? 223 LEU   B CA  1 
ATOM   1652 C C   . LEU   B 1 8   ? 50.637 15.905 -9.120  1.00 72.31  ? 223 LEU   B C   1 
ATOM   1653 O O   . LEU   B 1 8   ? 49.604 16.172 -8.493  1.00 69.75  ? 223 LEU   B O   1 
ATOM   1654 C CB  . LEU   B 1 8   ? 49.350 15.344 -11.182 1.00 69.99  ? 223 LEU   B CB  1 
ATOM   1655 C CG  . LEU   B 1 8   ? 49.544 16.403 -12.265 1.00 68.77  ? 223 LEU   B CG  1 
ATOM   1656 C CD1 . LEU   B 1 8   ? 48.243 16.616 -13.013 1.00 67.15  ? 223 LEU   B CD1 1 
ATOM   1657 C CD2 . LEU   B 1 8   ? 50.041 17.682 -11.660 1.00 66.90  ? 223 LEU   B CD2 1 
ATOM   1658 N N   . GLY   B 1 9   ? 51.819 16.379 -8.758  1.00 70.57  ? 224 GLY   B N   1 
ATOM   1659 C CA  . GLY   B 1 9   ? 51.889 17.316 -7.658  1.00 70.29  ? 224 GLY   B CA  1 
ATOM   1660 C C   . GLY   B 1 9   ? 53.257 17.333 -7.039  1.00 72.25  ? 224 GLY   B C   1 
ATOM   1661 O O   . GLY   B 1 9   ? 54.053 16.411 -7.208  1.00 73.49  ? 224 GLY   B O   1 
ATOM   1662 N N   . THR   B 1 10  ? 53.541 18.424 -6.333  1.00 73.09  ? 225 THR   B N   1 
ATOM   1663 C CA  . THR   B 1 10  ? 54.803 18.525 -5.636  1.00 75.59  ? 225 THR   B CA  1 
ATOM   1664 C C   . THR   B 1 10  ? 54.543 18.341 -4.150  1.00 77.50  ? 225 THR   B C   1 
ATOM   1665 O O   . THR   B 1 10  ? 53.428 18.045 -3.711  1.00 77.19  ? 225 THR   B O   1 
ATOM   1666 C CB  . THR   B 1 10  ? 55.517 19.865 -5.873  1.00 77.14  ? 225 THR   B CB  1 
ATOM   1667 O OG1 . THR   B 1 10  ? 54.916 20.909 -5.081  1.00 77.16  ? 225 THR   B OG1 1 
ATOM   1668 C CG2 . THR   B 1 10  ? 55.516 20.251 -7.337  1.00 74.04  ? 225 THR   B CG2 1 
ATOM   1669 N N   . ALA   B 1 11  ? 55.574 18.556 -3.362  1.00 79.67  ? 226 ALA   B N   1 
ATOM   1670 C CA  . ALA   B 1 11  ? 55.468 18.419 -1.932  1.00 80.22  ? 226 ALA   B CA  1 
ATOM   1671 C C   . ALA   B 1 11  ? 54.733 19.585 -1.281  1.00 82.21  ? 226 ALA   B C   1 
ATOM   1672 O O   . ALA   B 1 11  ? 54.342 19.464 -0.122  1.00 84.74  ? 226 ALA   B O   1 
ATOM   1673 C CB  . ALA   B 1 11  ? 56.874 18.266 -1.368  1.00 85.09  ? 226 ALA   B CB  1 
ATOM   1674 N N   . ARG   B 1 12  ? 54.523 20.698 -1.992  1.00 80.62  ? 227 ARG   B N   1 
ATOM   1675 C CA  . ARG   B 1 12  ? 53.825 21.857 -1.451  1.00 79.72  ? 227 ARG   B CA  1 
ATOM   1676 C C   . ARG   B 1 12  ? 52.410 21.979 -1.977  1.00 78.59  ? 227 ARG   B C   1 
ATOM   1677 O O   . ARG   B 1 12  ? 51.642 22.812 -1.481  1.00 76.79  ? 227 ARG   B O   1 
ATOM   1678 C CB  . ARG   B 1 12  ? 54.576 23.144 -1.803  1.00 82.79  ? 227 ARG   B CB  1 
ATOM   1679 C CG  . ARG   B 1 12  ? 56.066 22.975 -1.921  1.00 84.90  ? 227 ARG   B CG  1 
ATOM   1680 C CD  . ARG   B 1 12  ? 56.728 24.304 -2.195  1.00 87.76  ? 227 ARG   B CD  1 
ATOM   1681 N NE  . ARG   B 1 12  ? 56.127 25.351 -1.383  1.00 89.46  ? 227 ARG   B NE  1 
ATOM   1682 C CZ  . ARG   B 1 12  ? 56.240 26.648 -1.632  1.00 91.93  ? 227 ARG   B CZ  1 
ATOM   1683 N NH1 . ARG   B 1 12  ? 56.917 27.092 -2.681  1.00 92.41  ? 227 ARG   B NH1 1 
ATOM   1684 N NH2 . ARG   B 1 12  ? 55.655 27.519 -0.812  1.00 92.52  ? 227 ARG   B NH2 1 
ATOM   1685 N N   . LEU   B 1 13  ? 52.071 21.222 -3.008  1.00 76.82  ? 228 LEU   B N   1 
ATOM   1686 C CA  . LEU   B 1 13  ? 50.739 21.293 -3.576  1.00 75.81  ? 228 LEU   B CA  1 
ATOM   1687 C C   . LEU   B 1 13  ? 50.550 20.037 -4.396  1.00 73.18  ? 228 LEU   B C   1 
ATOM   1688 O O   . LEU   B 1 13  ? 51.378 19.722 -5.253  1.00 73.98  ? 228 LEU   B O   1 
ATOM   1689 C CB  . LEU   B 1 13  ? 50.551 22.533 -4.446  1.00 74.39  ? 228 LEU   B CB  1 
ATOM   1690 C CG  . LEU   B 1 13  ? 49.089 22.736 -4.825  1.00 72.16  ? 228 LEU   B CG  1 
ATOM   1691 C CD1 . LEU   B 1 13  ? 48.309 23.137 -3.566  1.00 73.88  ? 228 LEU   B CD1 1 
ATOM   1692 C CD2 . LEU   B 1 13  ? 48.940 23.770 -5.921  1.00 70.37  ? 228 LEU   B CD2 1 
ATOM   1693 N N   . GLN   B 1 14  ? 49.469 19.330 -4.134  1.00 69.04  ? 229 GLN   B N   1 
ATOM   1694 C CA  . GLN   B 1 14  ? 49.168 18.092 -4.822  1.00 68.96  ? 229 GLN   B CA  1 
ATOM   1695 C C   . GLN   B 1 14  ? 47.780 18.194 -5.422  1.00 68.56  ? 229 GLN   B C   1 
ATOM   1696 O O   . GLN   B 1 14  ? 46.865 18.744 -4.805  1.00 67.52  ? 229 GLN   B O   1 
ATOM   1697 C CB  . GLN   B 1 14  ? 49.273 16.898 -3.868  1.00 70.51  ? 229 GLN   B CB  1 
ATOM   1698 C CG  . GLN   B 1 14  ? 48.351 15.726 -4.196  1.00 72.05  ? 229 GLN   B CG  1 
ATOM   1699 C CD  . GLN   B 1 14  ? 48.932 14.392 -3.776  1.00 75.33  ? 229 GLN   B CD  1 
ATOM   1700 O OE1 . GLN   B 1 14  ? 49.913 13.923 -4.359  1.00 83.44  ? 229 GLN   B OE1 1 
ATOM   1701 N NE2 . GLN   B 1 14  ? 48.351 13.786 -2.741  1.00 79.60  ? 229 GLN   B NE2 1 
ATOM   1702 N N   . LEU   B 1 15  ? 47.637 17.702 -6.644  1.00 66.60  ? 230 LEU   B N   1 
ATOM   1703 C CA  . LEU   B 1 15  ? 46.327 17.599 -7.258  1.00 67.89  ? 230 LEU   B CA  1 
ATOM   1704 C C   . LEU   B 1 15  ? 45.647 16.343 -6.751  1.00 69.54  ? 230 LEU   B C   1 
ATOM   1705 O O   . LEU   B 1 15  ? 46.272 15.281 -6.647  1.00 70.40  ? 230 LEU   B O   1 
ATOM   1706 C CB  . LEU   B 1 15  ? 46.435 17.549 -8.779  1.00 67.77  ? 230 LEU   B CB  1 
ATOM   1707 C CG  . LEU   B 1 15  ? 45.091 17.454 -9.507  1.00 66.08  ? 230 LEU   B CG  1 
ATOM   1708 C CD1 . LEU   B 1 15  ? 44.566 18.852 -9.786  1.00 64.37  ? 230 LEU   B CD1 1 
ATOM   1709 C CD2 . LEU   B 1 15  ? 45.179 16.625 -10.807 1.00 66.22  ? 230 LEU   B CD2 1 
ATOM   1710 N N   . VAL   B 1 16  ? 44.371 16.468 -6.408  1.00 66.19  ? 231 VAL   B N   1 
ATOM   1711 C CA  . VAL   B 1 16  ? 43.606 15.353 -5.892  1.00 70.92  ? 231 VAL   B CA  1 
ATOM   1712 C C   . VAL   B 1 16  ? 42.519 14.917 -6.861  1.00 68.63  ? 231 VAL   B C   1 
ATOM   1713 O O   . VAL   B 1 16  ? 42.275 13.723 -7.034  1.00 70.70  ? 231 VAL   B O   1 
ATOM   1714 C CB  . VAL   B 1 16  ? 43.007 15.719 -4.528  1.00 70.57  ? 231 VAL   B CB  1 
ATOM   1715 C CG1 . VAL   B 1 16  ? 41.807 14.828 -4.242  1.00 71.85  ? 231 VAL   B CG1 1 
ATOM   1716 C CG2 . VAL   B 1 16  ? 44.089 15.622 -3.464  1.00 71.61  ? 231 VAL   B CG2 1 
ATOM   1717 N N   . GLU   B 1 17  ? 41.846 15.867 -7.481  1.00 66.17  ? 232 GLU   B N   1 
ATOM   1718 C CA  . GLU   B 1 17  ? 40.798 15.557 -8.431  1.00 65.58  ? 232 GLU   B CA  1 
ATOM   1719 C C   . GLU   B 1 17  ? 40.790 16.647 -9.477  1.00 63.92  ? 232 GLU   B C   1 
ATOM   1720 O O   . GLU   B 1 17  ? 40.890 17.832 -9.148  1.00 61.02  ? 232 GLU   B O   1 
ATOM   1721 C CB  . GLU   B 1 17  ? 39.407 15.457 -7.781  1.00 63.52  ? 232 GLU   B CB  1 
ATOM   1722 C CG  . GLU   B 1 17  ? 38.329 14.978 -8.792  1.00 65.95  ? 232 GLU   B CG  1 
ATOM   1723 C CD  . GLU   B 1 17  ? 37.761 13.612 -8.420  1.00 73.18  ? 232 GLU   B CD  1 
ATOM   1724 O OE1 . GLU   B 1 17  ? 38.453 12.883 -7.676  1.00 72.53  ? 232 GLU   B OE1 1 
ATOM   1725 O OE2 . GLU   B 1 17  ? 36.645 13.255 -8.881  1.00 75.93  ? 232 GLU   B OE2 1 
ATOM   1726 N N   . PHE   B 1 18  ? 40.664 16.233 -10.729 1.00 60.71  ? 233 PHE   B N   1 
ATOM   1727 C CA  . PHE   B 1 18  ? 40.417 17.139 -11.831 1.00 61.10  ? 233 PHE   B CA  1 
ATOM   1728 C C   . PHE   B 1 18  ? 39.474 16.446 -12.786 1.00 60.43  ? 233 PHE   B C   1 
ATOM   1729 O O   . PHE   B 1 18  ? 39.707 15.291 -13.156 1.00 59.49  ? 233 PHE   B O   1 
ATOM   1730 C CB  . PHE   B 1 18  ? 41.692 17.514 -12.579 1.00 60.96  ? 233 PHE   B CB  1 
ATOM   1731 C CG  . PHE   B 1 18  ? 41.425 18.415 -13.735 1.00 60.98  ? 233 PHE   B CG  1 
ATOM   1732 C CD1 . PHE   B 1 18  ? 41.236 19.770 -13.537 1.00 60.26  ? 233 PHE   B CD1 1 
ATOM   1733 C CD2 . PHE   B 1 18  ? 41.272 17.904 -15.010 1.00 59.23  ? 233 PHE   B CD2 1 
ATOM   1734 C CE1 . PHE   B 1 18  ? 40.952 20.589 -14.592 1.00 60.67  ? 233 PHE   B CE1 1 
ATOM   1735 C CE2 . PHE   B 1 18  ? 40.992 18.726 -16.055 1.00 59.08  ? 233 PHE   B CE2 1 
ATOM   1736 C CZ  . PHE   B 1 18  ? 40.832 20.059 -15.854 1.00 60.12  ? 233 PHE   B CZ  1 
ATOM   1737 N N   . SER   B 1 19  ? 38.425 17.141 -13.203 1.00 58.16  ? 234 SER   B N   1 
ATOM   1738 C CA  . SER   B 1 19  ? 37.545 16.541 -14.185 1.00 61.30  ? 234 SER   B CA  1 
ATOM   1739 C C   . SER   B 1 19  ? 36.856 17.647 -14.961 1.00 59.14  ? 234 SER   B C   1 
ATOM   1740 O O   . SER   B 1 19  ? 36.793 18.801 -14.526 1.00 55.45  ? 234 SER   B O   1 
ATOM   1741 C CB  . SER   B 1 19  ? 36.517 15.599 -13.530 1.00 61.65  ? 234 SER   B CB  1 
ATOM   1742 O OG  . SER   B 1 19  ? 35.698 16.326 -12.646 1.00 57.30  ? 234 SER   B OG  1 
ATOM   1743 N N   . ALA   B 1 20  ? 36.373 17.270 -16.146 1.00 58.93  ? 235 ALA   B N   1 
ATOM   1744 C CA  . ALA   B 1 20  ? 35.592 18.111 -17.037 1.00 59.78  ? 235 ALA   B CA  1 
ATOM   1745 C C   . ALA   B 1 20  ? 34.438 17.242 -17.483 1.00 57.44  ? 235 ALA   B C   1 
ATOM   1746 O O   . ALA   B 1 20  ? 34.648 16.077 -17.829 1.00 57.15  ? 235 ALA   B O   1 
ATOM   1747 C CB  . ALA   B 1 20  ? 36.419 18.582 -18.238 1.00 59.32  ? 235 ALA   B CB  1 
ATOM   1748 N N   . PHE   B 1 21  ? 33.224 17.780 -17.437 1.00 50.98  ? 236 PHE   B N   1 
ATOM   1749 C CA  . PHE   B 1 21  ? 32.060 16.916 -17.495 1.00 58.80  ? 236 PHE   B CA  1 
ATOM   1750 C C   . PHE   B 1 21  ? 30.902 17.707 -18.054 1.00 57.36  ? 236 PHE   B C   1 
ATOM   1751 O O   . PHE   B 1 21  ? 30.917 18.935 -18.056 1.00 56.81  ? 236 PHE   B O   1 
ATOM   1752 C CB  . PHE   B 1 21  ? 31.673 16.360 -16.096 1.00 65.57  ? 236 PHE   B CB  1 
ATOM   1753 C CG  . PHE   B 1 21  ? 31.367 17.433 -15.057 1.00 59.55  ? 236 PHE   B CG  1 
ATOM   1754 C CD1 . PHE   B 1 21  ? 30.098 17.959 -14.932 1.00 61.81  ? 236 PHE   B CD1 1 
ATOM   1755 C CD2 . PHE   B 1 21  ? 32.353 17.890 -14.196 1.00 63.09  ? 236 PHE   B CD2 1 
ATOM   1756 C CE1 . PHE   B 1 21  ? 29.824 18.932 -13.984 1.00 66.10  ? 236 PHE   B CE1 1 
ATOM   1757 C CE2 . PHE   B 1 21  ? 32.093 18.861 -13.247 1.00 61.61  ? 236 PHE   B CE2 1 
ATOM   1758 C CZ  . PHE   B 1 21  ? 30.829 19.385 -13.138 1.00 61.75  ? 236 PHE   B CZ  1 
ATOM   1759 N N   . VAL   B 1 22  ? 29.878 16.992 -18.495 1.00 63.89  ? 237 VAL   B N   1 
ATOM   1760 C CA  . VAL   B 1 22  ? 28.606 17.600 -18.852 1.00 69.78  ? 237 VAL   B CA  1 
ATOM   1761 C C   . VAL   B 1 22  ? 27.512 16.856 -18.109 1.00 66.43  ? 237 VAL   B C   1 
ATOM   1762 O O   . VAL   B 1 22  ? 27.554 15.624 -17.992 1.00 61.05  ? 237 VAL   B O   1 
ATOM   1763 C CB  . VAL   B 1 22  ? 28.339 17.556 -20.368 1.00 65.23  ? 237 VAL   B CB  1 
ATOM   1764 C CG1 . VAL   B 1 22  ? 28.385 16.124 -20.854 1.00 64.18  ? 237 VAL   B CG1 1 
ATOM   1765 C CG2 . VAL   B 1 22  ? 26.993 18.179 -20.678 1.00 66.93  ? 237 VAL   B CG2 1 
ATOM   1766 N N   . GLU   B 1 23  ? 26.526 17.600 -17.620 1.00 68.12  ? 238 GLU   B N   1 
ATOM   1767 C CA  . GLU   B 1 23  ? 25.356 16.996 -17.012 1.00 73.51  ? 238 GLU   B CA  1 
ATOM   1768 C C   . GLU   B 1 23  ? 24.179 17.291 -17.918 1.00 72.92  ? 238 GLU   B C   1 
ATOM   1769 O O   . GLU   B 1 23  ? 23.906 18.462 -18.214 1.00 73.24  ? 238 GLU   B O   1 
ATOM   1770 C CB  . GLU   B 1 23  ? 25.100 17.534 -15.594 1.00 70.72  ? 238 GLU   B CB  1 
ATOM   1771 C CG  . GLU   B 1 23  ? 26.139 17.115 -14.560 1.00 70.90  ? 238 GLU   B CG  1 
ATOM   1772 C CD  . GLU   B 1 23  ? 26.167 18.023 -13.329 1.00 68.93  ? 238 GLU   B CD  1 
ATOM   1773 O OE1 . GLU   B 1 23  ? 25.486 19.072 -13.326 1.00 66.82  ? 238 GLU   B OE1 1 
ATOM   1774 O OE2 . GLU   B 1 23  ? 26.886 17.693 -12.363 1.00 68.80  ? 238 GLU   B OE2 1 
ATOM   1775 N N   . PRO   B 1 24  ? 23.468 16.277 -18.402 1.00 76.15  ? 239 PRO   B N   1 
ATOM   1776 C CA  . PRO   B 1 24  ? 22.407 16.552 -19.360 1.00 79.67  ? 239 PRO   B CA  1 
ATOM   1777 C C   . PRO   B 1 24  ? 21.254 17.277 -18.680 1.00 83.73  ? 239 PRO   B C   1 
ATOM   1778 O O   . PRO   B 1 24  ? 21.050 17.134 -17.464 1.00 84.65  ? 239 PRO   B O   1 
ATOM   1779 C CB  . PRO   B 1 24  ? 21.986 15.148 -19.826 1.00 82.06  ? 239 PRO   B CB  1 
ATOM   1780 C CG  . PRO   B 1 24  ? 22.282 14.284 -18.605 1.00 81.25  ? 239 PRO   B CG  1 
ATOM   1781 C CD  . PRO   B 1 24  ? 23.514 14.863 -17.985 1.00 76.00  ? 239 PRO   B CD  1 
ATOM   1782 N N   . PRO   B 1 25  ? 20.485 18.068 -19.431 1.00 84.33  ? 240 PRO   B N   1 
ATOM   1783 C CA  . PRO   B 1 25  ? 19.427 18.872 -18.782 1.00 85.94  ? 240 PRO   B CA  1 
ATOM   1784 C C   . PRO   B 1 25  ? 18.427 18.046 -17.992 1.00 89.00  ? 240 PRO   B C   1 
ATOM   1785 O O   . PRO   B 1 25  ? 17.745 18.602 -17.123 1.00 90.67  ? 240 PRO   B O   1 
ATOM   1786 C CB  . PRO   B 1 25  ? 18.757 19.617 -19.949 1.00 84.93  ? 240 PRO   B CB  1 
ATOM   1787 C CG  . PRO   B 1 25  ? 19.509 19.217 -21.198 1.00 85.47  ? 240 PRO   B CG  1 
ATOM   1788 C CD  . PRO   B 1 25  ? 20.382 18.051 -20.899 1.00 83.93  ? 240 PRO   B CD  1 
ATOM   1789 N N   . ASP   B 1 26  ? 18.320 16.744 -18.254 1.00 87.91  ? 241 ASP   B N   1 
ATOM   1790 C CA  . ASP   B 1 26  ? 17.437 15.866 -17.501 1.00 89.83  ? 241 ASP   B CA  1 
ATOM   1791 C C   . ASP   B 1 26  ? 18.149 15.182 -16.331 1.00 92.12  ? 241 ASP   B C   1 
ATOM   1792 O O   . ASP   B 1 26  ? 17.662 14.160 -15.832 1.00 92.57  ? 241 ASP   B O   1 
ATOM   1793 C CB  . ASP   B 1 26  ? 16.815 14.813 -18.422 1.00 89.54  ? 241 ASP   B CB  1 
ATOM   1794 C CG  . ASP   B 1 26  ? 17.814 14.246 -19.409 1.00 91.07  ? 241 ASP   B CG  1 
ATOM   1795 O OD1 . ASP   B 1 26  ? 18.737 13.552 -18.925 1.00 92.77  ? 241 ASP   B OD1 1 
ATOM   1796 O OD2 . ASP   B 1 26  ? 17.739 14.542 -20.639 1.00 89.87  ? 241 ASP   B OD2 1 
ATOM   1797 N N   . ALA   B 1 27  ? 19.289 15.717 -15.887 1.00 94.53  ? 242 ALA   B N   1 
ATOM   1798 C CA  . ALA   B 1 27  ? 19.925 15.205 -14.680 1.00 94.38  ? 242 ALA   B CA  1 
ATOM   1799 C C   . ALA   B 1 27  ? 19.150 15.560 -13.415 1.00 97.09  ? 242 ALA   B C   1 
ATOM   1800 O O   . ALA   B 1 27  ? 19.423 14.980 -12.358 1.00 94.54  ? 242 ALA   B O   1 
ATOM   1801 C CB  . ALA   B 1 27  ? 21.358 15.728 -14.580 1.00 87.82  ? 242 ALA   B CB  1 
ATOM   1802 N N   . VAL   B 1 28  ? 18.198 16.493 -13.508 1.00 98.22  ? 243 VAL   B N   1 
ATOM   1803 C CA  . VAL   B 1 28  ? 17.363 16.856 -12.369 1.00 98.21  ? 243 VAL   B CA  1 
ATOM   1804 C C   . VAL   B 1 28  ? 16.401 15.728 -12.032 1.00 100.79 ? 243 VAL   B C   1 
ATOM   1805 O O   . VAL   B 1 28  ? 16.043 15.529 -10.863 1.00 102.37 ? 243 VAL   B O   1 
ATOM   1806 C CB  . VAL   B 1 28  ? 16.613 18.166 -12.667 1.00 97.68  ? 243 VAL   B CB  1 
ATOM   1807 C CG1 . VAL   B 1 28  ? 16.143 18.818 -11.379 1.00 101.18 ? 243 VAL   B CG1 1 
ATOM   1808 C CG2 . VAL   B 1 28  ? 17.500 19.120 -13.425 1.00 99.89  ? 243 VAL   B CG2 1 
ATOM   1809 N N   . ASP   B 1 29  ? 15.937 14.998 -13.046 1.00 94.82  ? 244 ASP   B N   1 
ATOM   1810 C CA  . ASP   B 1 29  ? 15.121 13.810 -12.827 1.00 96.57  ? 244 ASP   B CA  1 
ATOM   1811 C C   . ASP   B 1 29  ? 15.994 12.662 -12.348 1.00 96.74  ? 244 ASP   B C   1 
ATOM   1812 O O   . ASP   B 1 29  ? 15.879 12.218 -11.207 1.00 98.01  ? 244 ASP   B O   1 
ATOM   1813 C CB  . ASP   B 1 29  ? 14.378 13.418 -14.102 1.00 98.52  ? 244 ASP   B CB  1 
ATOM   1814 C CG  . ASP   B 1 29  ? 13.648 14.588 -14.730 1.00 99.68  ? 244 ASP   B CG  1 
ATOM   1815 O OD1 . ASP   B 1 29  ? 13.352 15.559 -13.995 1.00 99.11  ? 244 ASP   B OD1 1 
ATOM   1816 O OD2 . ASP   B 1 29  ? 13.353 14.530 -15.949 1.00 100.21 ? 244 ASP   B OD2 1 
ATOM   1817 N N   . SER   B 1 30  ? 16.876 12.171 -13.203 1.00 96.13  ? 245 SER   B N   1 
ATOM   1818 C CA  . SER   B 1 30  ? 17.811 11.126 -12.812 1.00 94.97  ? 245 SER   B CA  1 
ATOM   1819 C C   . SER   B 1 30  ? 19.214 11.642 -13.091 1.00 90.71  ? 245 SER   B C   1 
ATOM   1820 O O   . SER   B 1 30  ? 19.603 11.823 -14.250 1.00 90.79  ? 245 SER   B O   1 
ATOM   1821 C CB  . SER   B 1 30  ? 17.526 9.823  -13.549 1.00 95.21  ? 245 SER   B CB  1 
ATOM   1822 O OG  . SER   B 1 30  ? 17.846 8.727  -12.711 1.00 99.61  ? 245 SER   B OG  1 
ATOM   1823 N N   . TYR   B 1 31  ? 19.958 11.911 -12.032 1.00 88.90  ? 246 TYR   B N   1 
ATOM   1824 C CA  . TYR   B 1 31  ? 21.270 12.499 -12.194 1.00 84.44  ? 246 TYR   B CA  1 
ATOM   1825 C C   . TYR   B 1 31  ? 22.179 11.586 -13.005 1.00 80.89  ? 246 TYR   B C   1 
ATOM   1826 O O   . TYR   B 1 31  ? 22.041 10.364 -12.997 1.00 82.68  ? 246 TYR   B O   1 
ATOM   1827 C CB  . TYR   B 1 31  ? 21.895 12.766 -10.837 1.00 81.93  ? 246 TYR   B CB  1 
ATOM   1828 C CG  . TYR   B 1 31  ? 23.280 13.336 -10.947 1.00 77.38  ? 246 TYR   B CG  1 
ATOM   1829 C CD1 . TYR   B 1 31  ? 23.468 14.631 -11.397 1.00 77.27  ? 246 TYR   B CD1 1 
ATOM   1830 C CD2 . TYR   B 1 31  ? 24.401 12.585 -10.613 1.00 75.79  ? 246 TYR   B CD2 1 
ATOM   1831 C CE1 . TYR   B 1 31  ? 24.727 15.172 -11.504 1.00 73.83  ? 246 TYR   B CE1 1 
ATOM   1832 C CE2 . TYR   B 1 31  ? 25.667 13.117 -10.721 1.00 73.81  ? 246 TYR   B CE2 1 
ATOM   1833 C CZ  . TYR   B 1 31  ? 25.820 14.417 -11.168 1.00 72.18  ? 246 TYR   B CZ  1 
ATOM   1834 O OH  . TYR   B 1 31  ? 27.059 14.997 -11.288 1.00 70.15  ? 246 TYR   B OH  1 
ATOM   1835 N N   . GLN   B 1 32  ? 23.132 12.204 -13.691 1.00 76.02  ? 247 GLN   B N   1 
ATOM   1836 C CA  . GLN   B 1 32  ? 24.225 11.515 -14.358 1.00 73.44  ? 247 GLN   B CA  1 
ATOM   1837 C C   . GLN   B 1 32  ? 25.142 12.593 -14.904 1.00 69.42  ? 247 GLN   B C   1 
ATOM   1838 O O   . GLN   B 1 32  ? 24.726 13.742 -15.079 1.00 70.91  ? 247 GLN   B O   1 
ATOM   1839 C CB  . GLN   B 1 32  ? 23.732 10.616 -15.488 1.00 74.29  ? 247 GLN   B CB  1 
ATOM   1840 C CG  . GLN   B 1 32  ? 23.283 11.393 -16.695 1.00 75.63  ? 247 GLN   B CG  1 
ATOM   1841 C CD  . GLN   B 1 32  ? 22.659 10.502 -17.764 1.00 79.44  ? 247 GLN   B CD  1 
ATOM   1842 O OE1 . GLN   B 1 32  ? 22.280 10.968 -18.838 1.00 79.16  ? 247 GLN   B OE1 1 
ATOM   1843 N NE2 . GLN   B 1 32  ? 22.509 9.217  -17.450 1.00 79.15  ? 247 GLN   B NE2 1 
ATOM   1844 N N   . ARG   B 1 33  ? 26.390 12.227 -15.171 1.00 65.81  ? 248 ARG   B N   1 
ATOM   1845 C CA  . ARG   B 1 33  ? 27.257 13.197 -15.819 1.00 64.54  ? 248 ARG   B CA  1 
ATOM   1846 C C   . ARG   B 1 33  ? 28.266 12.450 -16.677 1.00 61.61  ? 248 ARG   B C   1 
ATOM   1847 O O   . ARG   B 1 33  ? 28.737 11.373 -16.303 1.00 61.39  ? 248 ARG   B O   1 
ATOM   1848 C CB  . ARG   B 1 33  ? 27.980 14.088 -14.805 1.00 63.28  ? 248 ARG   B CB  1 
ATOM   1849 C CG  . ARG   B 1 33  ? 29.108 13.436 -14.045 1.00 60.60  ? 248 ARG   B CG  1 
ATOM   1850 C CD  . ARG   B 1 33  ? 29.220 14.096 -12.711 1.00 63.85  ? 248 ARG   B CD  1 
ATOM   1851 N NE  . ARG   B 1 33  ? 30.582 14.449 -12.339 1.00 66.04  ? 248 ARG   B NE  1 
ATOM   1852 C CZ  . ARG   B 1 33  ? 30.871 15.199 -11.285 1.00 68.68  ? 248 ARG   B CZ  1 
ATOM   1853 N NH1 . ARG   B 1 33  ? 29.914 15.635 -10.468 1.00 66.19  ? 248 ARG   B NH1 1 
ATOM   1854 N NH2 . ARG   B 1 33  ? 32.147 15.499 -11.030 1.00 65.41  ? 248 ARG   B NH2 1 
ATOM   1855 N N   . HIS   B 1 34  ? 28.566 13.008 -17.840 1.00 63.91  ? 249 HIS   B N   1 
ATOM   1856 C CA  . HIS   B 1 34  ? 29.582 12.455 -18.714 1.00 61.46  ? 249 HIS   B CA  1 
ATOM   1857 C C   . HIS   B 1 34  ? 30.894 13.164 -18.430 1.00 60.63  ? 249 HIS   B C   1 
ATOM   1858 O O   . HIS   B 1 34  ? 30.954 14.403 -18.428 1.00 60.62  ? 249 HIS   B O   1 
ATOM   1859 C CB  . HIS   B 1 34  ? 29.192 12.624 -20.183 1.00 64.15  ? 249 HIS   B CB  1 
ATOM   1860 C CG  . HIS   B 1 34  ? 30.279 12.256 -21.146 1.00 63.65  ? 249 HIS   B CG  1 
ATOM   1861 N ND1 . HIS   B 1 34  ? 30.450 10.972 -21.617 1.00 64.61  ? 249 HIS   B ND1 1 
ATOM   1862 C CD2 . HIS   B 1 34  ? 31.255 13.004 -21.722 1.00 64.16  ? 249 HIS   B CD2 1 
ATOM   1863 C CE1 . HIS   B 1 34  ? 31.481 10.945 -22.447 1.00 66.15  ? 249 HIS   B CE1 1 
ATOM   1864 N NE2 . HIS   B 1 34  ? 31.992 12.164 -22.521 1.00 64.87  ? 249 HIS   B NE2 1 
ATOM   1865 N N   . LEU   B 1 35  ? 31.935 12.375 -18.199 1.00 54.94  ? 250 LEU   B N   1 
ATOM   1866 C CA  . LEU   B 1 35  ? 33.279 12.881 -17.959 1.00 59.41  ? 250 LEU   B CA  1 
ATOM   1867 C C   . LEU   B 1 35  ? 34.031 12.912 -19.294 1.00 62.42  ? 250 LEU   B C   1 
ATOM   1868 O O   . LEU   B 1 35  ? 34.237 11.869 -19.919 1.00 59.44  ? 250 LEU   B O   1 
ATOM   1869 C CB  . LEU   B 1 35  ? 33.994 11.998 -16.942 1.00 60.98  ? 250 LEU   B CB  1 
ATOM   1870 C CG  . LEU   B 1 35  ? 33.468 11.889 -15.505 1.00 59.70  ? 250 LEU   B CG  1 
ATOM   1871 C CD1 . LEU   B 1 35  ? 34.252 10.840 -14.778 1.00 59.88  ? 250 LEU   B CD1 1 
ATOM   1872 C CD2 . LEU   B 1 35  ? 33.623 13.213 -14.817 1.00 60.21  ? 250 LEU   B CD2 1 
ATOM   1873 N N   . PHE   B 1 36  ? 34.414 14.112 -19.741 1.00 58.90  ? 251 PHE   B N   1 
ATOM   1874 C CA  . PHE   B 1 36  ? 35.309 14.244 -20.882 1.00 61.39  ? 251 PHE   B CA  1 
ATOM   1875 C C   . PHE   B 1 36  ? 36.713 13.781 -20.528 1.00 59.96  ? 251 PHE   B C   1 
ATOM   1876 O O   . PHE   B 1 36  ? 37.309 12.961 -21.242 1.00 58.12  ? 251 PHE   B O   1 
ATOM   1877 C CB  . PHE   B 1 36  ? 35.336 15.695 -21.360 1.00 58.94  ? 251 PHE   B CB  1 
ATOM   1878 C CG  . PHE   B 1 36  ? 33.988 16.239 -21.702 1.00 59.78  ? 251 PHE   B CG  1 
ATOM   1879 C CD1 . PHE   B 1 36  ? 33.276 15.732 -22.783 1.00 60.48  ? 251 PHE   B CD1 1 
ATOM   1880 C CD2 . PHE   B 1 36  ? 33.453 17.280 -20.979 1.00 59.79  ? 251 PHE   B CD2 1 
ATOM   1881 C CE1 . PHE   B 1 36  ? 32.037 16.230 -23.112 1.00 61.53  ? 251 PHE   B CE1 1 
ATOM   1882 C CE2 . PHE   B 1 36  ? 32.213 17.792 -21.301 1.00 61.69  ? 251 PHE   B CE2 1 
ATOM   1883 C CZ  . PHE   B 1 36  ? 31.506 17.266 -22.371 1.00 63.44  ? 251 PHE   B CZ  1 
ATOM   1884 N N   . VAL   B 1 37  ? 37.261 14.292 -19.425 1.00 58.07  ? 252 VAL   B N   1 
ATOM   1885 C CA  . VAL   B 1 37  ? 38.544 13.829 -18.912 1.00 57.31  ? 252 VAL   B CA  1 
ATOM   1886 C C   . VAL   B 1 37  ? 38.458 13.779 -17.400 1.00 56.63  ? 252 VAL   B C   1 
ATOM   1887 O O   . VAL   B 1 37  ? 37.746 14.575 -16.784 1.00 58.10  ? 252 VAL   B O   1 
ATOM   1888 C CB  . VAL   B 1 37  ? 39.680 14.750 -19.366 1.00 55.23  ? 252 VAL   B CB  1 
ATOM   1889 C CG1 . VAL   B 1 37  ? 39.690 14.825 -20.892 1.00 58.37  ? 252 VAL   B CG1 1 
ATOM   1890 C CG2 . VAL   B 1 37  ? 39.454 16.114 -18.794 1.00 57.69  ? 252 VAL   B CG2 1 
ATOM   1891 N N   . HIS   B 1 38  ? 39.196 12.856 -16.787 1.00 56.91  ? 253 HIS   B N   1 
ATOM   1892 C CA  . HIS   B 1 38  ? 39.103 12.713 -15.338 1.00 60.81  ? 253 HIS   B CA  1 
ATOM   1893 C C   . HIS   B 1 38  ? 40.455 12.351 -14.760 1.00 61.28  ? 253 HIS   B C   1 
ATOM   1894 O O   . HIS   B 1 38  ? 41.093 11.412 -15.227 1.00 60.65  ? 253 HIS   B O   1 
ATOM   1895 C CB  . HIS   B 1 38  ? 38.097 11.626 -14.937 1.00 58.47  ? 253 HIS   B CB  1 
ATOM   1896 C CG  . HIS   B 1 38  ? 37.808 11.586 -13.472 1.00 61.47  ? 253 HIS   B CG  1 
ATOM   1897 N ND1 . HIS   B 1 38  ? 37.636 10.406 -12.777 1.00 62.58  ? 253 HIS   B ND1 1 
ATOM   1898 C CD2 . HIS   B 1 38  ? 37.651 12.579 -12.561 1.00 64.06  ? 253 HIS   B CD2 1 
ATOM   1899 C CE1 . HIS   B 1 38  ? 37.392 10.671 -11.504 1.00 65.26  ? 253 HIS   B CE1 1 
ATOM   1900 N NE2 . HIS   B 1 38  ? 37.398 11.983 -11.343 1.00 64.94  ? 253 HIS   B NE2 1 
ATOM   1901 N N   . ILE   B 1 39  ? 40.894 13.065 -13.739 1.00 59.44  ? 254 ILE   B N   1 
ATOM   1902 C CA  . ILE   B 1 39  ? 42.042 12.603 -12.980 1.00 63.36  ? 254 ILE   B CA  1 
ATOM   1903 C C   . ILE   B 1 39  ? 41.630 12.588 -11.534 1.00 66.20  ? 254 ILE   B C   1 
ATOM   1904 O O   . ILE   B 1 39  ? 41.023 13.543 -11.042 1.00 63.23  ? 254 ILE   B O   1 
ATOM   1905 C CB  . ILE   B 1 39  ? 43.289 13.483 -13.142 1.00 63.73  ? 254 ILE   B CB  1 
ATOM   1906 C CG1 . ILE   B 1 39  ? 43.669 13.629 -14.598 1.00 62.37  ? 254 ILE   B CG1 1 
ATOM   1907 C CG2 . ILE   B 1 39  ? 44.458 12.866 -12.405 1.00 63.60  ? 254 ILE   B CG2 1 
ATOM   1908 C CD1 . ILE   B 1 39  ? 44.876 14.501 -14.771 1.00 60.87  ? 254 ILE   B CD1 1 
ATOM   1909 N N   . SER   B 1 40  ? 41.959 11.524 -10.851 1.00 68.25  ? 255 SER   B N   1 
ATOM   1910 C CA  . SER   B 1 40  ? 41.635 11.452 -9.458  1.00 72.14  ? 255 SER   B CA  1 
ATOM   1911 C C   . SER   B 1 40  ? 42.772 10.717 -8.801  1.00 76.18  ? 255 SER   B C   1 
ATOM   1912 O O   . SER   B 1 40  ? 43.159 9.632  -9.253  1.00 76.06  ? 255 SER   B O   1 
ATOM   1913 C CB  . SER   B 1 40  ? 40.289 10.780 -9.281  1.00 72.57  ? 255 SER   B CB  1 
ATOM   1914 O OG  . SER   B 1 40  ? 40.462 9.438  -8.991  1.00 77.15  ? 255 SER   B OG  1 
ATOM   1915 N N   . GLN   B 1 41  ? 43.325 11.330 -7.759  1.00 77.32  ? 256 GLN   B N   1 
ATOM   1916 C CA  . GLN   B 1 41  ? 44.519 10.824 -7.111  1.00 78.69  ? 256 GLN   B CA  1 
ATOM   1917 C C   . GLN   B 1 41  ? 44.267 10.464 -5.656  1.00 82.67  ? 256 GLN   B C   1 
ATOM   1918 O O   . GLN   B 1 41  ? 45.222 10.345 -4.878  1.00 84.65  ? 256 GLN   B O   1 
ATOM   1919 C CB  . GLN   B 1 41  ? 45.665 11.823 -7.263  1.00 74.36  ? 256 GLN   B CB  1 
ATOM   1920 C CG  . GLN   B 1 41  ? 45.916 12.170 -8.735  1.00 73.12  ? 256 GLN   B CG  1 
ATOM   1921 C CD  . GLN   B 1 41  ? 47.355 12.574 -9.008  1.00 70.89  ? 256 GLN   B CD  1 
ATOM   1922 O OE1 . GLN   B 1 41  ? 48.095 11.833 -9.665  1.00 70.45  ? 256 GLN   B OE1 1 
ATOM   1923 N NE2 . GLN   B 1 41  ? 47.754 13.751 -8.529  1.00 69.94  ? 256 GLN   B NE2 1 
ATOM   1924 N N   . HIS   B 1 42  ? 42.994 10.311 -5.276  1.00 83.15  ? 257 HIS   B N   1 
ATOM   1925 C CA  A HIS   B 1 42  ? 42.697 9.843  -3.911  0.50 84.39  ? 257 HIS   B CA  1 
ATOM   1926 C CA  B HIS   B 1 42  ? 42.549 9.575  -4.096  0.50 84.52  ? 257 HIS   B CA  1 
ATOM   1927 C C   . HIS   B 1 42  ? 43.646 8.737  -3.457  1.00 87.76  ? 257 HIS   B C   1 
ATOM   1928 O O   . HIS   B 1 42  ? 43.398 8.044  -2.458  1.00 88.20  ? 257 HIS   B O   1 
ATOM   1929 C CB  A HIS   B 1 42  ? 41.257 9.350  -3.801  0.50 83.77  ? 257 HIS   B CB  1 
ATOM   1930 C CB  B HIS   B 1 42  ? 41.376 8.667  -4.490  0.50 84.27  ? 257 HIS   B CB  1 
ATOM   1931 C CG  A HIS   B 1 42  ? 40.251 10.401 -4.134  0.50 82.48  ? 257 HIS   B CG  1 
ATOM   1932 C CG  B HIS   B 1 42  ? 41.605 7.933  -5.780  0.50 84.85  ? 257 HIS   B CG  1 
ATOM   1933 N ND1 A HIS   B 1 42  ? 39.847 10.658 -5.426  0.50 81.53  ? 257 HIS   B ND1 1 
ATOM   1934 N ND1 B HIS   B 1 42  ? 40.608 7.698  -6.705  0.50 84.19  ? 257 HIS   B ND1 1 
ATOM   1935 C CD2 A HIS   B 1 42  ? 39.587 11.279 -3.347  0.50 81.23  ? 257 HIS   B CD2 1 
ATOM   1936 C CD2 B HIS   B 1 42  ? 42.739 7.423  -6.317  0.50 84.21  ? 257 HIS   B CD2 1 
ATOM   1937 C CE1 A HIS   B 1 42  ? 38.967 11.642 -5.417  0.50 80.77  ? 257 HIS   B CE1 1 
ATOM   1938 C CE1 B HIS   B 1 42  ? 41.109 7.036  -7.734  0.50 82.93  ? 257 HIS   B CE1 1 
ATOM   1939 N NE2 A HIS   B 1 42  ? 38.791 12.036 -4.169  0.50 81.64  ? 257 HIS   B NE2 1 
ATOM   1940 N NE2 B HIS   B 1 42  ? 42.403 6.867  -7.528  0.50 83.95  ? 257 HIS   B NE2 1 
ATOM   1941 N N   . ALA   B 1 48  ? 54.454 2.387  -5.380  1.00 127.44 ? 263 ALA   B N   1 
ATOM   1942 C CA  . ALA   B 1 48  ? 54.315 3.130  -6.630  1.00 125.41 ? 263 ALA   B CA  1 
ATOM   1943 C C   . ALA   B 1 48  ? 55.680 3.466  -7.233  1.00 124.46 ? 263 ALA   B C   1 
ATOM   1944 O O   . ALA   B 1 48  ? 56.683 3.530  -6.519  1.00 124.50 ? 263 ALA   B O   1 
ATOM   1945 C CB  . ALA   B 1 48  ? 53.509 4.399  -6.407  1.00 122.58 ? 263 ALA   B CB  1 
ATOM   1946 N N   . PRO   B 1 49  ? 55.720 3.650  -8.550  1.00 128.31 ? 264 PRO   B N   1 
ATOM   1947 C CA  . PRO   B 1 49  ? 56.965 4.045  -9.212  1.00 124.99 ? 264 PRO   B CA  1 
ATOM   1948 C C   . PRO   B 1 49  ? 56.897 5.489  -9.674  1.00 123.08 ? 264 PRO   B C   1 
ATOM   1949 O O   . PRO   B 1 49  ? 55.797 6.038  -9.857  1.00 120.99 ? 264 PRO   B O   1 
ATOM   1950 C CB  . PRO   B 1 49  ? 57.030 3.081  -10.402 1.00 123.21 ? 264 PRO   B CB  1 
ATOM   1951 C CG  . PRO   B 1 49  ? 55.569 2.929  -10.794 1.00 125.25 ? 264 PRO   B CG  1 
ATOM   1952 C CD  . PRO   B 1 49  ? 54.732 3.151  -9.525  1.00 129.32 ? 264 PRO   B CD  1 
ATOM   1953 N N   . PRO   B 1 50  ? 58.044 6.148  -9.866  1.00 120.46 ? 265 PRO   B N   1 
ATOM   1954 C CA  . PRO   B 1 50  ? 58.019 7.527  -10.363 1.00 113.81 ? 265 PRO   B CA  1 
ATOM   1955 C C   . PRO   B 1 50  ? 57.335 7.603  -11.718 1.00 105.13 ? 265 PRO   B C   1 
ATOM   1956 O O   . PRO   B 1 50  ? 57.351 6.652  -12.501 1.00 106.44 ? 265 PRO   B O   1 
ATOM   1957 C CB  . PRO   B 1 50  ? 59.503 7.901  -10.463 1.00 113.18 ? 265 PRO   B CB  1 
ATOM   1958 C CG  . PRO   B 1 50  ? 60.203 6.951  -9.553  1.00 116.09 ? 265 PRO   B CG  1 
ATOM   1959 C CD  . PRO   B 1 50  ? 59.418 5.677  -9.621  1.00 119.76 ? 265 PRO   B CD  1 
ATOM   1960 N N   . LEU   B 1 51  ? 56.713 8.746  -11.982 1.00 97.76  ? 266 LEU   B N   1 
ATOM   1961 C CA  . LEU   B 1 51  ? 56.109 8.950  -13.283 1.00 92.41  ? 266 LEU   B CA  1 
ATOM   1962 C C   . LEU   B 1 51  ? 57.177 8.901  -14.367 1.00 91.56  ? 266 LEU   B C   1 
ATOM   1963 O O   . LEU   B 1 51  ? 58.372 9.071  -14.111 1.00 92.93  ? 266 LEU   B O   1 
ATOM   1964 C CB  . LEU   B 1 51  ? 55.374 10.282 -13.328 1.00 87.87  ? 266 LEU   B CB  1 
ATOM   1965 C CG  . LEU   B 1 51  ? 54.184 10.359 -12.382 1.00 88.99  ? 266 LEU   B CG  1 
ATOM   1966 C CD1 . LEU   B 1 51  ? 53.634 11.771 -12.333 1.00 84.59  ? 266 LEU   B CD1 1 
ATOM   1967 C CD2 . LEU   B 1 51  ? 53.120 9.388  -12.832 1.00 87.45  ? 266 LEU   B CD2 1 
ATOM   1968 N N   . GLU   B 1 52  ? 56.739 8.647  -15.594 1.00 83.09  ? 267 GLU   B N   1 
ATOM   1969 C CA  . GLU   B 1 52  ? 57.692 8.686  -16.686 1.00 81.62  ? 267 GLU   B CA  1 
ATOM   1970 C C   . GLU   B 1 52  ? 57.984 10.134 -17.035 1.00 77.88  ? 267 GLU   B C   1 
ATOM   1971 O O   . GLU   B 1 52  ? 57.220 11.037 -16.700 1.00 79.37  ? 267 GLU   B O   1 
ATOM   1972 C CB  . GLU   B 1 52  ? 57.156 7.934  -17.897 1.00 83.96  ? 267 GLU   B CB  1 
ATOM   1973 C CG  . GLU   B 1 52  ? 57.060 6.450  -17.672 1.00 88.18  ? 267 GLU   B CG  1 
ATOM   1974 C CD  . GLU   B 1 52  ? 56.440 5.725  -18.845 1.00 97.63  ? 267 GLU   B CD  1 
ATOM   1975 O OE1 . GLU   B 1 52  ? 56.653 6.158  -20.002 1.00 95.38  ? 267 GLU   B OE1 1 
ATOM   1976 O OE2 . GLU   B 1 52  ? 55.743 4.715  -18.608 1.00 104.37 ? 267 GLU   B OE2 1 
ATOM   1977 N N   . SER   B 1 53  ? 59.115 10.360 -17.689 1.00 78.31  ? 268 SER   B N   1 
ATOM   1978 C CA  . SER   B 1 53  ? 59.489 11.710 -18.067 1.00 77.87  ? 268 SER   B CA  1 
ATOM   1979 C C   . SER   B 1 53  ? 59.311 11.911 -19.560 1.00 77.44  ? 268 SER   B C   1 
ATOM   1980 O O   . SER   B 1 53  ? 59.449 10.976 -20.352 1.00 78.30  ? 268 SER   B O   1 
ATOM   1981 C CB  . SER   B 1 53  ? 60.937 12.031 -17.696 1.00 79.59  ? 268 SER   B CB  1 
ATOM   1982 O OG  . SER   B 1 53  ? 61.828 11.074 -18.206 1.00 76.83  ? 268 SER   B OG  1 
ATOM   1983 N N   . VAL   B 1 54  ? 58.999 13.146 -19.930 1.00 79.92  ? 269 VAL   B N   1 
ATOM   1984 C CA  . VAL   B 1 54  ? 59.054 13.611 -21.307 1.00 80.64  ? 269 VAL   B CA  1 
ATOM   1985 C C   . VAL   B 1 54  ? 59.888 14.883 -21.316 1.00 83.82  ? 269 VAL   B C   1 
ATOM   1986 O O   . VAL   B 1 54  ? 59.762 15.722 -20.417 1.00 83.73  ? 269 VAL   B O   1 
ATOM   1987 C CB  . VAL   B 1 54  ? 57.647 13.872 -21.872 1.00 79.01  ? 269 VAL   B CB  1 
ATOM   1988 C CG1 . VAL   B 1 54  ? 57.731 14.582 -23.193 1.00 79.03  ? 269 VAL   B CG1 1 
ATOM   1989 C CG2 . VAL   B 1 54  ? 56.898 12.574 -21.996 1.00 78.62  ? 269 VAL   B CG2 1 
ATOM   1990 N N   . ASP   B 1 55  ? 60.755 15.021 -22.311 1.00 83.30  ? 270 ASP   B N   1 
ATOM   1991 C CA  . ASP   B 1 55  ? 61.646 16.171 -22.358 1.00 86.42  ? 270 ASP   B CA  1 
ATOM   1992 C C   . ASP   B 1 55  ? 60.834 17.391 -22.794 1.00 88.43  ? 270 ASP   B C   1 
ATOM   1993 O O   . ASP   B 1 55  ? 60.266 17.406 -23.896 1.00 89.34  ? 270 ASP   B O   1 
ATOM   1994 C CB  . ASP   B 1 55  ? 62.812 15.903 -23.310 1.00 89.51  ? 270 ASP   B CB  1 
ATOM   1995 C CG  . ASP   B 1 55  ? 63.655 17.136 -23.568 1.00 92.69  ? 270 ASP   B CG  1 
ATOM   1996 O OD1 . ASP   B 1 55  ? 63.103 18.251 -23.721 1.00 91.22  ? 270 ASP   B OD1 1 
ATOM   1997 O OD2 . ASP   B 1 55  ? 64.894 16.975 -23.618 1.00 97.27  ? 270 ASP   B OD2 1 
ATOM   1998 N N   . VAL   B 1 56  ? 60.781 18.415 -21.934 1.00 90.89  ? 271 VAL   B N   1 
ATOM   1999 C CA  . VAL   B 1 56  ? 59.946 19.584 -22.211 1.00 93.14  ? 271 VAL   B CA  1 
ATOM   2000 C C   . VAL   B 1 56  ? 60.242 20.131 -23.602 1.00 94.27  ? 271 VAL   B C   1 
ATOM   2001 O O   . VAL   B 1 56  ? 59.343 20.585 -24.321 1.00 95.58  ? 271 VAL   B O   1 
ATOM   2002 C CB  . VAL   B 1 56  ? 60.154 20.658 -21.128 1.00 92.49  ? 271 VAL   B CB  1 
ATOM   2003 C CG1 . VAL   B 1 56  ? 61.623 21.012 -20.997 1.00 95.87  ? 271 VAL   B CG1 1 
ATOM   2004 C CG2 . VAL   B 1 56  ? 59.315 21.887 -21.430 1.00 91.24  ? 271 VAL   B CG2 1 
ATOM   2005 N N   . ARG   B 1 57  ? 61.517 20.102 -24.000 1.00 90.92  ? 272 ARG   B N   1 
ATOM   2006 C CA  . ARG   B 1 57  ? 61.902 20.631 -25.306 1.00 92.74  ? 272 ARG   B CA  1 
ATOM   2007 C C   . ARG   B 1 57  ? 60.948 20.142 -26.393 1.00 93.65  ? 272 ARG   B C   1 
ATOM   2008 O O   . ARG   B 1 57  ? 60.661 20.863 -27.354 1.00 94.84  ? 272 ARG   B O   1 
ATOM   2009 C CB  . ARG   B 1 57  ? 63.332 20.209 -25.666 1.00 93.70  ? 272 ARG   B CB  1 
ATOM   2010 C CG  . ARG   B 1 57  ? 64.481 20.701 -24.786 1.00 95.40  ? 272 ARG   B CG  1 
ATOM   2011 C CD  . ARG   B 1 57  ? 65.720 19.897 -25.197 1.00 98.73  ? 272 ARG   B CD  1 
ATOM   2012 N NE  . ARG   B 1 57  ? 66.845 19.902 -24.269 1.00 104.54 ? 272 ARG   B NE  1 
ATOM   2013 C CZ  . ARG   B 1 57  ? 67.368 20.993 -23.725 1.00 109.14 ? 272 ARG   B CZ  1 
ATOM   2014 N NH1 . ARG   B 1 57  ? 66.755 22.165 -23.797 1.00 109.73 ? 272 ARG   B NH1 1 
ATOM   2015 N NH2 . ARG   B 1 57  ? 68.534 20.908 -23.086 1.00 112.74 ? 272 ARG   B NH2 1 
ATOM   2016 N N   . GLN   B 1 58  ? 60.451 18.908 -26.255 1.00 92.14  ? 273 GLN   B N   1 
ATOM   2017 C CA  . GLN   B 1 58  ? 59.647 18.274 -27.292 1.00 90.80  ? 273 GLN   B CA  1 
ATOM   2018 C C   . GLN   B 1 58  ? 58.228 18.814 -27.384 1.00 92.99  ? 273 GLN   B C   1 
ATOM   2019 O O   . GLN   B 1 58  ? 57.504 18.423 -28.306 1.00 91.77  ? 273 GLN   B O   1 
ATOM   2020 C CB  . GLN   B 1 58  ? 59.608 16.765 -27.058 1.00 93.45  ? 273 GLN   B CB  1 
ATOM   2021 C CG  . GLN   B 1 58  ? 60.822 16.013 -27.608 1.00 95.90  ? 273 GLN   B CG  1 
ATOM   2022 C CD  . GLN   B 1 58  ? 61.074 16.284 -29.082 1.00 98.97  ? 273 GLN   B CD  1 
ATOM   2023 O OE1 . GLN   B 1 58  ? 61.939 17.091 -29.450 1.00 101.18 ? 273 GLN   B OE1 1 
ATOM   2024 N NE2 . GLN   B 1 58  ? 60.322 15.599 -29.942 1.00 100.22 ? 273 GLN   B NE2 1 
ATOM   2025 N N   . ILE   B 1 59  ? 57.809 19.693 -26.475 1.00 98.79  ? 274 ILE   B N   1 
ATOM   2026 C CA  . ILE   B 1 59  ? 56.487 20.299 -26.548 1.00 97.99  ? 274 ILE   B CA  1 
ATOM   2027 C C   . ILE   B 1 59  ? 56.543 21.818 -26.688 1.00 99.30  ? 274 ILE   B C   1 
ATOM   2028 O O   . ILE   B 1 59  ? 55.489 22.462 -26.722 1.00 99.54  ? 274 ILE   B O   1 
ATOM   2029 C CB  . ILE   B 1 59  ? 55.619 19.898 -25.336 1.00 93.40  ? 274 ILE   B CB  1 
ATOM   2030 C CG1 . ILE   B 1 59  ? 56.452 19.823 -24.061 1.00 93.11  ? 274 ILE   B CG1 1 
ATOM   2031 C CG2 . ILE   B 1 59  ? 54.978 18.542 -25.548 1.00 87.41  ? 274 ILE   B CG2 1 
ATOM   2032 C CD1 . ILE   B 1 59  ? 55.596 19.863 -22.796 1.00 87.19  ? 274 ILE   B CD1 1 
ATOM   2033 N N   . TYR   B 1 60  ? 57.741 22.409 -26.803 1.00 96.75  ? 275 TYR   B N   1 
ATOM   2034 C CA  . TYR   B 1 60  ? 57.889 23.867 -26.846 1.00 99.78  ? 275 TYR   B CA  1 
ATOM   2035 C C   . TYR   B 1 60  ? 56.964 24.535 -27.854 1.00 100.94 ? 275 TYR   B C   1 
ATOM   2036 O O   . TYR   B 1 60  ? 56.426 25.616 -27.589 1.00 101.89 ? 275 TYR   B O   1 
ATOM   2037 C CB  . TYR   B 1 60  ? 59.357 24.204 -27.134 1.00 101.16 ? 275 TYR   B CB  1 
ATOM   2038 C CG  . TYR   B 1 60  ? 60.249 24.201 -25.905 1.00 101.56 ? 275 TYR   B CG  1 
ATOM   2039 C CD1 . TYR   B 1 60  ? 59.962 23.373 -24.818 1.00 96.82  ? 275 TYR   B CD1 1 
ATOM   2040 C CD2 . TYR   B 1 60  ? 61.324 25.082 -25.788 1.00 101.45 ? 275 TYR   B CD2 1 
ATOM   2041 C CE1 . TYR   B 1 60  ? 60.755 23.384 -23.679 1.00 95.45  ? 275 TYR   B CE1 1 
ATOM   2042 C CE2 . TYR   B 1 60  ? 62.128 25.087 -24.653 1.00 103.69 ? 275 TYR   B CE2 1 
ATOM   2043 C CZ  . TYR   B 1 60  ? 61.834 24.250 -23.596 1.00 99.03  ? 275 TYR   B CZ  1 
ATOM   2044 O OH  . TYR   B 1 60  ? 62.626 24.264 -22.462 1.00 98.72  ? 275 TYR   B OH  1 
ATOM   2045 N N   . ASP   B 1 61  ? 56.788 23.924 -29.022 1.00 107.12 ? 276 ASP   B N   1 
ATOM   2046 C CA  . ASP   B 1 61  ? 56.043 24.546 -30.107 1.00 106.82 ? 276 ASP   B CA  1 
ATOM   2047 C C   . ASP   B 1 61  ? 54.532 24.438 -29.945 1.00 105.34 ? 276 ASP   B C   1 
ATOM   2048 O O   . ASP   B 1 61  ? 53.802 25.109 -30.684 1.00 104.25 ? 276 ASP   B O   1 
ATOM   2049 C CB  . ASP   B 1 61  ? 56.434 23.898 -31.429 1.00 112.30 ? 276 ASP   B CB  1 
ATOM   2050 C CG  . ASP   B 1 61  ? 56.567 22.399 -31.299 1.00 117.86 ? 276 ASP   B CG  1 
ATOM   2051 O OD1 . ASP   B 1 61  ? 57.597 21.944 -30.753 1.00 116.59 ? 276 ASP   B OD1 1 
ATOM   2052 O OD2 . ASP   B 1 61  ? 55.616 21.681 -31.686 1.00 119.14 ? 276 ASP   B OD2 1 
ATOM   2053 N N   . LYS   B 1 62  ? 54.046 23.609 -29.019 1.00 100.59 ? 277 LYS   B N   1 
ATOM   2054 C CA  . LYS   B 1 62  ? 52.614 23.421 -28.812 1.00 95.21  ? 277 LYS   B CA  1 
ATOM   2055 C C   . LYS   B 1 62  ? 51.996 24.445 -27.864 1.00 91.90  ? 277 LYS   B C   1 
ATOM   2056 O O   . LYS   B 1 62  ? 50.768 24.441 -27.696 1.00 87.05  ? 277 LYS   B O   1 
ATOM   2057 C CB  . LYS   B 1 62  ? 52.331 22.013 -28.285 1.00 91.62  ? 277 LYS   B CB  1 
ATOM   2058 C CG  . LYS   B 1 62  ? 53.191 20.918 -28.881 1.00 93.83  ? 277 LYS   B CG  1 
ATOM   2059 C CD  . LYS   B 1 62  ? 52.405 19.622 -29.017 1.00 88.31  ? 277 LYS   B CD  1 
ATOM   2060 C CE  . LYS   B 1 62  ? 51.402 19.715 -30.176 1.00 86.18  ? 277 LYS   B CE  1 
ATOM   2061 N NZ  . LYS   B 1 62  ? 52.008 19.426 -31.497 1.00 84.37  ? 277 LYS   B NZ  1 
ATOM   2062 N N   . PHE   B 1 63  ? 52.813 25.338 -27.262 1.00 93.81  ? 278 PHE   B N   1 
ATOM   2063 C CA  . PHE   B 1 63  ? 52.297 26.288 -26.273 1.00 94.52  ? 278 PHE   B CA  1 
ATOM   2064 C C   . PHE   B 1 63  ? 52.786 27.711 -26.536 1.00 98.75  ? 278 PHE   B C   1 
ATOM   2065 O O   . PHE   B 1 63  ? 53.652 27.916 -27.393 1.00 99.55  ? 278 PHE   B O   1 
ATOM   2066 C CB  . PHE   B 1 63  ? 52.668 25.819 -24.858 1.00 91.77  ? 278 PHE   B CB  1 
ATOM   2067 C CG  . PHE   B 1 63  ? 52.142 24.458 -24.528 1.00 85.43  ? 278 PHE   B CG  1 
ATOM   2068 C CD1 . PHE   B 1 63  ? 52.852 23.319 -24.896 1.00 84.36  ? 278 PHE   B CD1 1 
ATOM   2069 C CD2 . PHE   B 1 63  ? 50.924 24.311 -23.887 1.00 77.44  ? 278 PHE   B CD2 1 
ATOM   2070 C CE1 . PHE   B 1 63  ? 52.361 22.062 -24.607 1.00 82.13  ? 278 PHE   B CE1 1 
ATOM   2071 C CE2 . PHE   B 1 63  ? 50.425 23.055 -23.603 1.00 73.41  ? 278 PHE   B CE2 1 
ATOM   2072 C CZ  . PHE   B 1 63  ? 51.145 21.927 -23.963 1.00 74.30  ? 278 PHE   B CZ  1 
ATOM   2073 N N   . PRO   B 1 64  ? 52.281 28.731 -25.804 1.00 105.95 ? 279 PRO   B N   1 
ATOM   2074 C CA  . PRO   B 1 64  ? 52.622 30.118 -26.154 1.00 110.01 ? 279 PRO   B CA  1 
ATOM   2075 C C   . PRO   B 1 64  ? 54.095 30.446 -25.963 1.00 113.09 ? 279 PRO   B C   1 
ATOM   2076 O O   . PRO   B 1 64  ? 54.961 29.566 -26.014 1.00 112.45 ? 279 PRO   B O   1 
ATOM   2077 C CB  . PRO   B 1 64  ? 51.739 30.950 -25.212 1.00 108.79 ? 279 PRO   B CB  1 
ATOM   2078 C CG  . PRO   B 1 64  ? 51.504 30.088 -24.028 1.00 108.24 ? 279 PRO   B CG  1 
ATOM   2079 C CD  . PRO   B 1 64  ? 51.627 28.639 -24.482 1.00 104.05 ? 279 PRO   B CD  1 
ATOM   2080 N N   . GLU   B 1 65  ? 54.374 31.731 -25.736 1.00 119.14 ? 280 GLU   B N   1 
ATOM   2081 C CA  . GLU   B 1 65  ? 55.737 32.239 -25.705 1.00 123.53 ? 280 GLU   B CA  1 
ATOM   2082 C C   . GLU   B 1 65  ? 55.769 33.720 -25.346 1.00 127.65 ? 280 GLU   B C   1 
ATOM   2083 O O   . GLU   B 1 65  ? 54.763 34.273 -24.890 1.00 127.64 ? 280 GLU   B O   1 
ATOM   2084 C CB  . GLU   B 1 65  ? 56.400 31.985 -27.049 1.00 120.43 ? 280 GLU   B CB  1 
ATOM   2085 C CG  . GLU   B 1 65  ? 57.908 31.872 -27.024 1.00 121.77 ? 280 GLU   B CG  1 
ATOM   2086 C CD  . GLU   B 1 65  ? 58.410 30.716 -27.851 1.00 121.51 ? 280 GLU   B CD  1 
ATOM   2087 O OE1 . GLU   B 1 65  ? 57.569 29.918 -28.316 1.00 120.05 ? 280 GLU   B OE1 1 
ATOM   2088 O OE2 . GLU   B 1 65  ? 59.639 30.651 -28.084 1.00 117.91 ? 280 GLU   B OE2 1 
ATOM   2089 N N   . LYS   B 1 66  ? 56.924 34.364 -25.501 1.00 131.50 ? 281 LYS   B N   1 
ATOM   2090 C CA  . LYS   B 1 66  ? 57.042 35.796 -25.244 1.00 135.38 ? 281 LYS   B CA  1 
ATOM   2091 C C   . LYS   B 1 66  ? 56.904 36.129 -23.762 1.00 135.35 ? 281 LYS   B C   1 
ATOM   2092 O O   . LYS   B 1 66  ? 57.253 37.237 -23.343 1.00 140.13 ? 281 LYS   B O   1 
ATOM   2093 C CB  . LYS   B 1 66  ? 55.989 36.564 -26.045 1.00 137.69 ? 281 LYS   B CB  1 
ATOM   2094 N N   . LYS   B 1 67  ? 56.398 35.176 -22.976 1.00 127.07 ? 282 LYS   B N   1 
ATOM   2095 C CA  . LYS   B 1 67  ? 56.075 35.353 -21.565 1.00 123.23 ? 282 LYS   B CA  1 
ATOM   2096 C C   . LYS   B 1 67  ? 55.039 34.297 -21.209 1.00 125.03 ? 282 LYS   B C   1 
ATOM   2097 O O   . LYS   B 1 67  ? 54.356 33.782 -22.101 1.00 127.44 ? 282 LYS   B O   1 
ATOM   2098 C CB  . LYS   B 1 67  ? 55.563 36.773 -21.282 1.00 125.26 ? 282 LYS   B CB  1 
ATOM   2099 C CG  . LYS   B 1 67  ? 54.487 36.879 -20.204 1.00 122.32 ? 282 LYS   B CG  1 
ATOM   2100 N N   . GLY   B 1 68  ? 54.932 33.933 -19.932 1.00 116.78 ? 283 GLY   B N   1 
ATOM   2101 C CA  . GLY   B 1 68  ? 53.954 32.938 -19.526 1.00 111.01 ? 283 GLY   B CA  1 
ATOM   2102 C C   . GLY   B 1 68  ? 53.886 31.768 -20.484 1.00 110.30 ? 283 GLY   B C   1 
ATOM   2103 O O   . GLY   B 1 68  ? 52.822 31.173 -20.700 1.00 106.31 ? 283 GLY   B O   1 
ATOM   2104 N N   . GLY   B 1 69  ? 55.032 31.440 -21.075 1.00 107.69 ? 284 GLY   B N   1 
ATOM   2105 C CA  . GLY   B 1 69  ? 55.159 30.294 -21.955 1.00 104.90 ? 284 GLY   B CA  1 
ATOM   2106 C C   . GLY   B 1 69  ? 56.045 29.241 -21.317 1.00 99.86  ? 284 GLY   B C   1 
ATOM   2107 O O   . GLY   B 1 69  ? 56.975 29.568 -20.575 1.00 100.41 ? 284 GLY   B O   1 
ATOM   2108 N N   . LEU   B 1 70  ? 55.743 27.971 -21.612 1.00 103.96 ? 285 LEU   B N   1 
ATOM   2109 C CA  . LEU   B 1 70  ? 56.497 26.843 -21.070 1.00 100.55 ? 285 LEU   B CA  1 
ATOM   2110 C C   . LEU   B 1 70  ? 57.984 27.139 -20.928 1.00 103.63 ? 285 LEU   B C   1 
ATOM   2111 O O   . LEU   B 1 70  ? 58.561 26.962 -19.850 1.00 103.45 ? 285 LEU   B O   1 
ATOM   2112 C CB  . LEU   B 1 70  ? 56.307 25.628 -21.966 1.00 93.38  ? 285 LEU   B CB  1 
ATOM   2113 C CG  . LEU   B 1 70  ? 55.437 24.528 -21.405 1.00 88.95  ? 285 LEU   B CG  1 
ATOM   2114 C CD1 . LEU   B 1 70  ? 55.556 23.299 -22.286 1.00 87.89  ? 285 LEU   B CD1 1 
ATOM   2115 C CD2 . LEU   B 1 70  ? 55.836 24.238 -19.964 1.00 87.79  ? 285 LEU   B CD2 1 
ATOM   2116 N N   . ARG   B 1 71  ? 58.625 27.563 -22.024 1.00 99.56  ? 286 ARG   B N   1 
ATOM   2117 C CA  . ARG   B 1 71  ? 60.018 27.997 -22.015 1.00 101.84 ? 286 ARG   B CA  1 
ATOM   2118 C C   . ARG   B 1 71  ? 60.310 28.884 -20.816 1.00 101.51 ? 286 ARG   B C   1 
ATOM   2119 O O   . ARG   B 1 71  ? 61.107 28.525 -19.944 1.00 101.19 ? 286 ARG   B O   1 
ATOM   2120 C CB  . ARG   B 1 71  ? 60.357 28.755 -23.308 1.00 108.73 ? 286 ARG   B CB  1 
ATOM   2121 C CG  . ARG   B 1 71  ? 61.333 28.061 -24.263 1.00 111.22 ? 286 ARG   B CG  1 
ATOM   2122 C CD  . ARG   B 1 71  ? 61.554 28.871 -25.553 1.00 113.78 ? 286 ARG   B CD  1 
ATOM   2123 N NE  . ARG   B 1 71  ? 60.512 28.595 -26.541 1.00 120.08 ? 286 ARG   B NE  1 
ATOM   2124 C CZ  . ARG   B 1 71  ? 60.698 27.985 -27.705 1.00 120.08 ? 286 ARG   B CZ  1 
ATOM   2125 N NH1 . ARG   B 1 71  ? 61.904 27.626 -28.113 1.00 116.30 ? 286 ARG   B NH1 1 
ATOM   2126 N NH2 . ARG   B 1 71  ? 59.645 27.741 -28.486 1.00 117.50 ? 286 ARG   B NH2 1 
ATOM   2127 N N   . GLU   B 1 72  ? 59.686 30.061 -20.793 1.00 101.82 ? 287 GLU   B N   1 
ATOM   2128 C CA  . GLU   B 1 72  ? 59.938 31.028 -19.729 1.00 102.97 ? 287 GLU   B CA  1 
ATOM   2129 C C   . GLU   B 1 72  ? 59.650 30.423 -18.360 1.00 103.47 ? 287 GLU   B C   1 
ATOM   2130 O O   . GLU   B 1 72  ? 60.519 30.397 -17.475 1.00 104.46 ? 287 GLU   B O   1 
ATOM   2131 C CB  . GLU   B 1 72  ? 59.097 32.286 -19.972 1.00 106.91 ? 287 GLU   B CB  1 
ATOM   2132 C CG  . GLU   B 1 72  ? 59.861 33.552 -19.914 1.00 112.89 ? 287 GLU   B CG  1 
ATOM   2133 C CD  . GLU   B 1 72  ? 59.219 34.523 -18.954 1.00 118.80 ? 287 GLU   B CD  1 
ATOM   2134 O OE1 . GLU   B 1 72  ? 58.490 34.039 -18.060 1.00 117.40 ? 287 GLU   B OE1 1 
ATOM   2135 O OE2 . GLU   B 1 72  ? 59.459 35.751 -19.077 1.00 121.22 ? 287 GLU   B OE2 1 
ATOM   2136 N N   . LEU   B 1 73  ? 58.419 29.934 -18.169 1.00 109.45 ? 288 LEU   B N   1 
ATOM   2137 C CA  . LEU   B 1 73  ? 58.070 29.291 -16.905 1.00 107.32 ? 288 LEU   B CA  1 
ATOM   2138 C C   . LEU   B 1 73  ? 59.084 28.219 -16.540 1.00 106.44 ? 288 LEU   B C   1 
ATOM   2139 O O   . LEU   B 1 73  ? 59.601 28.185 -15.416 1.00 107.79 ? 288 LEU   B O   1 
ATOM   2140 C CB  . LEU   B 1 73  ? 56.669 28.672 -16.960 1.00 101.99 ? 288 LEU   B CB  1 
ATOM   2141 C CG  . LEU   B 1 73  ? 55.395 29.521 -16.945 1.00 101.22 ? 288 LEU   B CG  1 
ATOM   2142 C CD1 . LEU   B 1 73  ? 55.525 30.659 -15.959 1.00 105.05 ? 288 LEU   B CD1 1 
ATOM   2143 C CD2 . LEU   B 1 73  ? 55.054 30.036 -18.311 1.00 109.21 ? 288 LEU   B CD2 1 
ATOM   2144 N N   . TYR   B 1 74  ? 59.384 27.329 -17.486 1.00 101.93 ? 289 TYR   B N   1 
ATOM   2145 C CA  . TYR   B 1 74  ? 60.314 26.249 -17.193 1.00 98.99  ? 289 TYR   B CA  1 
ATOM   2146 C C   . TYR   B 1 74  ? 61.713 26.768 -16.918 1.00 104.56 ? 289 TYR   B C   1 
ATOM   2147 O O   . TYR   B 1 74  ? 62.508 26.073 -16.277 1.00 106.13 ? 289 TYR   B O   1 
ATOM   2148 C CB  . TYR   B 1 74  ? 60.346 25.229 -18.332 1.00 96.07  ? 289 TYR   B CB  1 
ATOM   2149 C CG  . TYR   B 1 74  ? 60.955 23.921 -17.902 1.00 94.01  ? 289 TYR   B CG  1 
ATOM   2150 C CD1 . TYR   B 1 74  ? 62.328 23.767 -17.838 1.00 98.76  ? 289 TYR   B CD1 1 
ATOM   2151 C CD2 . TYR   B 1 74  ? 60.163 22.847 -17.550 1.00 90.18  ? 289 TYR   B CD2 1 
ATOM   2152 C CE1 . TYR   B 1 74  ? 62.897 22.585 -17.431 1.00 97.99  ? 289 TYR   B CE1 1 
ATOM   2153 C CE2 . TYR   B 1 74  ? 60.724 21.654 -17.142 1.00 90.43  ? 289 TYR   B CE2 1 
ATOM   2154 C CZ  . TYR   B 1 74  ? 62.092 21.533 -17.083 1.00 93.68  ? 289 TYR   B CZ  1 
ATOM   2155 O OH  . TYR   B 1 74  ? 62.675 20.356 -16.686 1.00 93.33  ? 289 TYR   B OH  1 
ATOM   2156 N N   . ASP   B 1 75  ? 62.027 27.981 -17.372 1.00 106.96 ? 290 ASP   B N   1 
ATOM   2157 C CA  . ASP   B 1 75  ? 63.291 28.600 -16.991 1.00 107.42 ? 290 ASP   B CA  1 
ATOM   2158 C C   . ASP   B 1 75  ? 63.267 29.097 -15.553 1.00 106.96 ? 290 ASP   B C   1 
ATOM   2159 O O   . ASP   B 1 75  ? 64.158 28.764 -14.764 1.00 109.30 ? 290 ASP   B O   1 
ATOM   2160 C CB  . ASP   B 1 75  ? 63.631 29.757 -17.921 1.00 108.01 ? 290 ASP   B CB  1 
ATOM   2161 C CG  . ASP   B 1 75  ? 64.392 29.301 -19.130 1.00 109.40 ? 290 ASP   B CG  1 
ATOM   2162 O OD1 . ASP   B 1 75  ? 64.782 28.113 -19.129 1.00 110.62 ? 290 ASP   B OD1 1 
ATOM   2163 O OD2 . ASP   B 1 75  ? 64.685 30.140 -20.016 1.00 113.61 ? 290 ASP   B OD2 1 
ATOM   2164 N N   . ARG   B 1 76  ? 62.259 29.902 -15.200 1.00 109.13 ? 291 ARG   B N   1 
ATOM   2165 C CA  . ARG   B 1 76  ? 62.136 30.389 -13.828 1.00 110.72 ? 291 ARG   B CA  1 
ATOM   2166 C C   . ARG   B 1 76  ? 62.097 29.241 -12.821 1.00 107.48 ? 291 ARG   B C   1 
ATOM   2167 O O   . ARG   B 1 76  ? 62.454 29.429 -11.651 1.00 105.51 ? 291 ARG   B O   1 
ATOM   2168 C CB  . ARG   B 1 76  ? 60.884 31.265 -13.694 1.00 113.24 ? 291 ARG   B CB  1 
ATOM   2169 C CG  . ARG   B 1 76  ? 61.077 32.715 -14.132 1.00 116.07 ? 291 ARG   B CG  1 
ATOM   2170 C CD  . ARG   B 1 76  ? 59.896 33.206 -14.961 1.00 123.21 ? 291 ARG   B CD  1 
ATOM   2171 N NE  . ARG   B 1 76  ? 59.861 34.661 -15.068 1.00 132.43 ? 291 ARG   B NE  1 
ATOM   2172 C CZ  . ARG   B 1 76  ? 58.779 35.361 -15.383 1.00 133.88 ? 291 ARG   B CZ  1 
ATOM   2173 N NH1 . ARG   B 1 76  ? 57.621 34.768 -15.639 1.00 130.66 ? 291 ARG   B NH1 1 
ATOM   2174 N NH2 . ARG   B 1 76  ? 58.859 36.690 -15.442 1.00 129.93 ? 291 ARG   B NH2 1 
ATOM   2175 N N   . GLY   B 1 77  ? 61.666 28.055 -13.254 1.00 97.91  ? 292 GLY   B N   1 
ATOM   2176 C CA  . GLY   B 1 77  ? 61.697 26.875 -12.423 1.00 91.92  ? 292 GLY   B CA  1 
ATOM   2177 C C   . GLY   B 1 77  ? 60.565 26.835 -11.421 1.00 87.96  ? 292 GLY   B C   1 
ATOM   2178 O O   . GLY   B 1 77  ? 59.670 27.688 -11.427 1.00 88.21  ? 292 GLY   B O   1 
ATOM   2179 N N   . PRO   B 1 78  ? 60.582 25.832 -10.528 1.00 83.55  ? 293 PRO   B N   1 
ATOM   2180 C CA  . PRO   B 1 78  ? 61.543 24.727 -10.433 1.00 81.30  ? 293 PRO   B CA  1 
ATOM   2181 C C   . PRO   B 1 78  ? 61.081 23.533 -11.265 1.00 79.65  ? 293 PRO   B C   1 
ATOM   2182 O O   . PRO   B 1 78  ? 59.876 23.303 -11.397 1.00 78.67  ? 293 PRO   B O   1 
ATOM   2183 C CB  . PRO   B 1 78  ? 61.550 24.420 -8.932  1.00 79.61  ? 293 PRO   B CB  1 
ATOM   2184 C CG  . PRO   B 1 78  ? 60.108 24.662 -8.525  1.00 79.00  ? 293 PRO   B CG  1 
ATOM   2185 C CD  . PRO   B 1 78  ? 59.608 25.791 -9.419  1.00 81.25  ? 293 PRO   B CD  1 
ATOM   2186 N N   . PRO   B 1 79  ? 62.008 22.744 -11.817 1.00 79.73  ? 294 PRO   B N   1 
ATOM   2187 C CA  . PRO   B 1 79  ? 61.598 21.722 -12.801 1.00 80.81  ? 294 PRO   B CA  1 
ATOM   2188 C C   . PRO   B 1 79  ? 60.672 20.670 -12.222 1.00 77.34  ? 294 PRO   B C   1 
ATOM   2189 O O   . PRO   B 1 79  ? 59.819 20.140 -12.947 1.00 76.47  ? 294 PRO   B O   1 
ATOM   2190 C CB  . PRO   B 1 79  ? 62.931 21.119 -13.282 1.00 80.92  ? 294 PRO   B CB  1 
ATOM   2191 C CG  . PRO   B 1 79  ? 64.009 21.689 -12.410 1.00 77.17  ? 294 PRO   B CG  1 
ATOM   2192 C CD  . PRO   B 1 79  ? 63.420 22.632 -11.411 1.00 78.30  ? 294 PRO   B CD  1 
ATOM   2193 N N   . HIS   B 1 80  ? 60.788 20.373 -10.927 1.00 76.57  ? 295 HIS   B N   1 
ATOM   2194 C CA  . HIS   B 1 80  ? 59.936 19.360 -10.317 1.00 73.99  ? 295 HIS   B CA  1 
ATOM   2195 C C   . HIS   B 1 80  ? 58.485 19.779 -10.236 1.00 72.79  ? 295 HIS   B C   1 
ATOM   2196 O O   . HIS   B 1 80  ? 57.667 18.988 -9.762  1.00 71.32  ? 295 HIS   B O   1 
ATOM   2197 C CB  . HIS   B 1 80  ? 60.427 19.009 -8.919  1.00 75.32  ? 295 HIS   B CB  1 
ATOM   2198 C CG  . HIS   B 1 80  ? 60.149 20.067 -7.899  1.00 77.76  ? 295 HIS   B CG  1 
ATOM   2199 N ND1 . HIS   B 1 80  ? 61.050 21.065 -7.592  1.00 79.58  ? 295 HIS   B ND1 1 
ATOM   2200 C CD2 . HIS   B 1 80  ? 59.058 20.295 -7.131  1.00 76.05  ? 295 HIS   B CD2 1 
ATOM   2201 C CE1 . HIS   B 1 80  ? 60.528 21.856 -6.673  1.00 79.12  ? 295 HIS   B CE1 1 
ATOM   2202 N NE2 . HIS   B 1 80  ? 59.321 21.412 -6.378  1.00 77.58  ? 295 HIS   B NE2 1 
ATOM   2203 N N   . ALA   B 1 81  ? 58.139 20.981 -10.692 1.00 74.40  ? 296 ALA   B N   1 
ATOM   2204 C CA  . ALA   B 1 81  ? 56.771 21.481 -10.635 1.00 72.61  ? 296 ALA   B CA  1 
ATOM   2205 C C   . ALA   B 1 81  ? 55.985 21.251 -11.919 1.00 72.21  ? 296 ALA   B C   1 
ATOM   2206 O O   . ALA   B 1 81  ? 54.762 21.448 -11.916 1.00 70.39  ? 296 ALA   B O   1 
ATOM   2207 C CB  . ALA   B 1 81  ? 56.778 22.980 -10.328 1.00 71.54  ? 296 ALA   B CB  1 
ATOM   2208 N N   . PHE   B 1 82  ? 56.649 20.857 -13.004 1.00 71.11  ? 297 PHE   B N   1 
ATOM   2209 C CA  . PHE   B 1 82  ? 56.058 20.831 -14.338 1.00 73.29  ? 297 PHE   B CA  1 
ATOM   2210 C C   . PHE   B 1 82  ? 55.673 19.412 -14.726 1.00 74.29  ? 297 PHE   B C   1 
ATOM   2211 O O   . PHE   B 1 82  ? 56.480 18.487 -14.589 1.00 73.30  ? 297 PHE   B O   1 
ATOM   2212 C CB  . PHE   B 1 82  ? 57.035 21.399 -15.367 1.00 77.81  ? 297 PHE   B CB  1 
ATOM   2213 C CG  . PHE   B 1 82  ? 57.256 22.869 -15.231 1.00 79.04  ? 297 PHE   B CG  1 
ATOM   2214 C CD1 . PHE   B 1 82  ? 57.989 23.378 -14.172 1.00 80.57  ? 297 PHE   B CD1 1 
ATOM   2215 C CD2 . PHE   B 1 82  ? 56.703 23.749 -16.147 1.00 80.04  ? 297 PHE   B CD2 1 
ATOM   2216 C CE1 . PHE   B 1 82  ? 58.183 24.731 -14.036 1.00 84.25  ? 297 PHE   B CE1 1 
ATOM   2217 C CE2 . PHE   B 1 82  ? 56.890 25.104 -16.017 1.00 85.11  ? 297 PHE   B CE2 1 
ATOM   2218 C CZ  . PHE   B 1 82  ? 57.635 25.598 -14.960 1.00 86.92  ? 297 PHE   B CZ  1 
ATOM   2219 N N   . PHE   B 1 83  ? 54.459 19.253 -15.251 1.00 70.61  ? 298 PHE   B N   1 
ATOM   2220 C CA  . PHE   B 1 83  ? 53.931 17.953 -15.625 1.00 71.37  ? 298 PHE   B CA  1 
ATOM   2221 C C   . PHE   B 1 83  ? 53.228 18.048 -16.968 1.00 67.70  ? 298 PHE   B C   1 
ATOM   2222 O O   . PHE   B 1 83  ? 52.666 19.088 -17.310 1.00 62.72  ? 298 PHE   B O   1 
ATOM   2223 C CB  . PHE   B 1 83  ? 52.949 17.429 -14.572 1.00 69.74  ? 298 PHE   B CB  1 
ATOM   2224 C CG  . PHE   B 1 83  ? 53.586 17.108 -13.271 1.00 71.13  ? 298 PHE   B CG  1 
ATOM   2225 C CD1 . PHE   B 1 83  ? 53.742 18.085 -12.300 1.00 70.39  ? 298 PHE   B CD1 1 
ATOM   2226 C CD2 . PHE   B 1 83  ? 54.029 15.829 -13.013 1.00 69.66  ? 298 PHE   B CD2 1 
ATOM   2227 C CE1 . PHE   B 1 83  ? 54.332 17.791 -11.104 1.00 70.59  ? 298 PHE   B CE1 1 
ATOM   2228 C CE2 . PHE   B 1 83  ? 54.626 15.528 -11.814 1.00 74.12  ? 298 PHE   B CE2 1 
ATOM   2229 C CZ  . PHE   B 1 83  ? 54.772 16.512 -10.852 1.00 72.08  ? 298 PHE   B CZ  1 
ATOM   2230 N N   . LEU   B 1 84  ? 53.240 16.944 -17.713 1.00 70.65  ? 299 LEU   B N   1 
ATOM   2231 C CA  . LEU   B 1 84  ? 52.477 16.806 -18.950 1.00 67.67  ? 299 LEU   B CA  1 
ATOM   2232 C C   . LEU   B 1 84  ? 51.424 15.727 -18.749 1.00 62.34  ? 299 LEU   B C   1 
ATOM   2233 O O   . LEU   B 1 84  ? 51.762 14.593 -18.397 1.00 63.80  ? 299 LEU   B O   1 
ATOM   2234 C CB  . LEU   B 1 84  ? 53.393 16.451 -20.122 1.00 67.14  ? 299 LEU   B CB  1 
ATOM   2235 C CG  . LEU   B 1 84  ? 52.840 15.873 -21.429 1.00 65.69  ? 299 LEU   B CG  1 
ATOM   2236 C CD1 . LEU   B 1 84  ? 52.201 16.957 -22.268 1.00 66.00  ? 299 LEU   B CD1 1 
ATOM   2237 C CD2 . LEU   B 1 84  ? 53.938 15.215 -22.228 1.00 68.63  ? 299 LEU   B CD2 1 
ATOM   2238 N N   . VAL   B 1 85  ? 50.152 16.079 -18.937 1.00 61.40  ? 300 VAL   B N   1 
ATOM   2239 C CA  . VAL   B 1 85  ? 49.070 15.103 -18.971 1.00 61.82  ? 300 VAL   B CA  1 
ATOM   2240 C C   . VAL   B 1 85  ? 48.632 14.942 -20.419 1.00 61.53  ? 300 VAL   B C   1 
ATOM   2241 O O   . VAL   B 1 85  ? 48.372 15.937 -21.111 1.00 59.70  ? 300 VAL   B O   1 
ATOM   2242 C CB  . VAL   B 1 85  ? 47.879 15.517 -18.086 1.00 59.99  ? 300 VAL   B CB  1 
ATOM   2243 C CG1 . VAL   B 1 85  ? 46.857 14.389 -18.044 1.00 60.27  ? 300 VAL   B CG1 1 
ATOM   2244 C CG2 . VAL   B 1 85  ? 48.340 15.844 -16.679 1.00 59.98  ? 300 VAL   B CG2 1 
ATOM   2245 N N   . LYS   B 1 86  ? 48.607 13.702 -20.895 1.00 59.60  ? 301 LYS   B N   1 
ATOM   2246 C CA  . LYS   B 1 86  ? 47.944 13.372 -22.146 1.00 60.42  ? 301 LYS   B CA  1 
ATOM   2247 C C   . LYS   B 1 86  ? 46.597 12.734 -21.811 1.00 59.27  ? 301 LYS   B C   1 
ATOM   2248 O O   . LYS   B 1 86  ? 46.546 11.729 -21.097 1.00 60.18  ? 301 LYS   B O   1 
ATOM   2249 C CB  . LYS   B 1 86  ? 48.802 12.444 -23.006 1.00 60.26  ? 301 LYS   B CB  1 
ATOM   2250 C CG  . LYS   B 1 86  ? 48.020 11.744 -24.096 1.00 62.82  ? 301 LYS   B CG  1 
ATOM   2251 C CD  . LYS   B 1 86  ? 48.526 12.133 -25.480 1.00 66.58  ? 301 LYS   B CD  1 
ATOM   2252 C CE  . LYS   B 1 86  ? 48.060 11.153 -26.537 1.00 69.25  ? 301 LYS   B CE  1 
ATOM   2253 N NZ  . LYS   B 1 86  ? 48.904 11.168 -27.745 1.00 73.11  ? 301 LYS   B NZ  1 
ATOM   2254 N N   . PHE   B 1 87  ? 45.520 13.353 -22.295 1.00 56.48  ? 302 PHE   B N   1 
ATOM   2255 C CA  . PHE   B 1 87  ? 44.148 12.897 -22.154 1.00 59.72  ? 302 PHE   B CA  1 
ATOM   2256 C C   . PHE   B 1 87  ? 43.686 12.206 -23.428 1.00 63.74  ? 302 PHE   B C   1 
ATOM   2257 O O   . PHE   B 1 87  ? 43.937 12.693 -24.538 1.00 59.92  ? 302 PHE   B O   1 
ATOM   2258 C CB  . PHE   B 1 87  ? 43.221 14.082 -21.908 1.00 58.51  ? 302 PHE   B CB  1 
ATOM   2259 C CG  . PHE   B 1 87  ? 43.203 14.572 -20.507 1.00 60.21  ? 302 PHE   B CG  1 
ATOM   2260 C CD1 . PHE   B 1 87  ? 42.989 13.702 -19.446 1.00 58.29  ? 302 PHE   B CD1 1 
ATOM   2261 C CD2 . PHE   B 1 87  ? 43.385 15.906 -20.251 1.00 58.29  ? 302 PHE   B CD2 1 
ATOM   2262 C CE1 . PHE   B 1 87  ? 42.951 14.159 -18.140 1.00 58.15  ? 302 PHE   B CE1 1 
ATOM   2263 C CE2 . PHE   B 1 87  ? 43.343 16.382 -18.940 1.00 60.20  ? 302 PHE   B CE2 1 
ATOM   2264 C CZ  . PHE   B 1 87  ? 43.136 15.493 -17.879 1.00 59.24  ? 302 PHE   B CZ  1 
ATOM   2265 N N   . TRP   B 1 88  ? 43.003 11.077 -23.259 1.00 60.83  ? 303 TRP   B N   1 
ATOM   2266 C CA  . TRP   B 1 88  ? 42.132 10.528 -24.278 1.00 63.68  ? 303 TRP   B CA  1 
ATOM   2267 C C   . TRP   B 1 88  ? 40.707 10.885 -23.869 1.00 63.43  ? 303 TRP   B C   1 
ATOM   2268 O O   . TRP   B 1 88  ? 40.037 10.167 -23.129 1.00 61.82  ? 303 TRP   B O   1 
ATOM   2269 C CB  . TRP   B 1 88  ? 42.345 9.037  -24.432 1.00 65.18  ? 303 TRP   B CB  1 
ATOM   2270 C CG  . TRP   B 1 88  ? 43.641 8.732  -25.094 1.00 67.10  ? 303 TRP   B CG  1 
ATOM   2271 C CD1 . TRP   B 1 88  ? 43.865 8.539  -26.430 1.00 66.95  ? 303 TRP   B CD1 1 
ATOM   2272 C CD2 . TRP   B 1 88  ? 44.905 8.584  -24.447 1.00 67.69  ? 303 TRP   B CD2 1 
ATOM   2273 N NE1 . TRP   B 1 88  ? 45.192 8.269  -26.647 1.00 67.85  ? 303 TRP   B NE1 1 
ATOM   2274 C CE2 . TRP   B 1 88  ? 45.856 8.310  -25.448 1.00 69.84  ? 303 TRP   B CE2 1 
ATOM   2275 C CE3 . TRP   B 1 88  ? 45.329 8.667  -23.111 1.00 67.31  ? 303 TRP   B CE3 1 
ATOM   2276 C CZ2 . TRP   B 1 88  ? 47.207 8.098  -25.158 1.00 73.96  ? 303 TRP   B CZ2 1 
ATOM   2277 C CZ3 . TRP   B 1 88  ? 46.673 8.457  -22.824 1.00 69.23  ? 303 TRP   B CZ3 1 
ATOM   2278 C CH2 . TRP   B 1 88  ? 47.595 8.187  -23.841 1.00 73.67  ? 303 TRP   B CH2 1 
ATOM   2279 N N   . ALA   B 1 89  ? 40.247 12.004 -24.389 1.00 59.45  ? 304 ALA   B N   1 
ATOM   2280 C CA  . ALA   B 1 89  ? 38.919 12.516 -24.098 1.00 63.72  ? 304 ALA   B CA  1 
ATOM   2281 C C   . ALA   B 1 89  ? 37.835 11.611 -24.664 1.00 65.37  ? 304 ALA   B C   1 
ATOM   2282 O O   . ALA   B 1 89  ? 37.868 11.246 -25.840 1.00 60.89  ? 304 ALA   B O   1 
ATOM   2283 C CB  . ALA   B 1 89  ? 38.779 13.925 -24.678 1.00 62.37  ? 304 ALA   B CB  1 
ATOM   2284 N N   . ASP   B 1 90  ? 36.860 11.278 -23.825 1.00 65.24  ? 305 ASP   B N   1 
ATOM   2285 C CA  . ASP   B 1 90  ? 35.637 10.631 -24.271 1.00 65.38  ? 305 ASP   B CA  1 
ATOM   2286 C C   . ASP   B 1 90  ? 34.691 11.691 -24.815 1.00 64.03  ? 305 ASP   B C   1 
ATOM   2287 O O   . ASP   B 1 90  ? 34.295 12.609 -24.087 1.00 65.23  ? 305 ASP   B O   1 
ATOM   2288 C CB  . ASP   B 1 90  ? 34.989 9.897  -23.105 1.00 65.54  ? 305 ASP   B CB  1 
ATOM   2289 C CG  . ASP   B 1 90  ? 33.765 9.124  -23.519 1.00 68.54  ? 305 ASP   B CG  1 
ATOM   2290 O OD1 . ASP   B 1 90  ? 33.347 9.213  -24.702 1.00 69.86  ? 305 ASP   B OD1 1 
ATOM   2291 O OD2 . ASP   B 1 90  ? 33.207 8.428  -22.656 1.00 69.43  ? 305 ASP   B OD2 1 
ATOM   2292 N N   . LEU   B 1 91  ? 34.327 11.581 -26.087 1.00 66.46  ? 306 LEU   B N   1 
ATOM   2293 C CA  . LEU   B 1 91  ? 33.480 12.584 -26.729 1.00 66.89  ? 306 LEU   B CA  1 
ATOM   2294 C C   . LEU   B 1 91  ? 32.153 12.003 -27.197 1.00 68.69  ? 306 LEU   B C   1 
ATOM   2295 O O   . LEU   B 1 91  ? 31.545 12.532 -28.131 1.00 72.01  ? 306 LEU   B O   1 
ATOM   2296 C CB  . LEU   B 1 91  ? 34.212 13.229 -27.905 1.00 64.41  ? 306 LEU   B CB  1 
ATOM   2297 C CG  . LEU   B 1 91  ? 35.481 13.965 -27.497 1.00 63.17  ? 306 LEU   B CG  1 
ATOM   2298 C CD1 . LEU   B 1 91  ? 36.046 14.710 -28.665 1.00 63.27  ? 306 LEU   B CD1 1 
ATOM   2299 C CD2 . LEU   B 1 91  ? 35.155 14.941 -26.367 1.00 62.82  ? 306 LEU   B CD2 1 
ATOM   2300 N N   . ASN   B 1 92  ? 31.704 10.924 -26.586 1.00 70.04  ? 307 ASN   B N   1 
ATOM   2301 C CA  . ASN   B 1 92  ? 30.455 10.261 -26.940 1.00 72.06  ? 307 ASN   B CA  1 
ATOM   2302 C C   . ASN   B 1 92  ? 29.502 10.411 -25.758 1.00 71.43  ? 307 ASN   B C   1 
ATOM   2303 O O   . ASN   B 1 92  ? 29.544 9.607  -24.820 1.00 70.54  ? 307 ASN   B O   1 
ATOM   2304 C CB  . ASN   B 1 92  ? 30.714 8.791  -27.259 1.00 74.75  ? 307 ASN   B CB  1 
ATOM   2305 C CG  . ASN   B 1 92  ? 29.559 8.142  -27.966 1.00 79.49  ? 307 ASN   B CG  1 
ATOM   2306 O OD1 . ASN   B 1 92  ? 29.527 8.042  -29.201 1.00 81.17  ? 307 ASN   B OD1 1 
ATOM   2307 N ND2 . ASN   B 1 92  ? 28.584 7.696  -27.184 1.00 79.38  ? 307 ASN   B ND2 1 
ATOM   2308 N N   . TRP   B 1 93  ? 28.640 11.427 -25.797 1.00 70.64  ? 308 TRP   B N   1 
ATOM   2309 C CA  . TRP   B 1 93  ? 27.771 11.657 -24.632 1.00 72.99  ? 308 TRP   B CA  1 
ATOM   2310 C C   . TRP   B 1 93  ? 26.310 12.002 -24.966 1.00 76.26  ? 308 TRP   B C   1 
ATOM   2311 O O   . TRP   B 1 93  ? 25.892 11.931 -26.132 1.00 76.41  ? 308 TRP   B O   1 
ATOM   2312 C CB  . TRP   B 1 93  ? 28.381 12.751 -23.748 1.00 69.14  ? 308 TRP   B CB  1 
ATOM   2313 C CG  . TRP   B 1 93  ? 28.181 14.164 -24.250 1.00 70.14  ? 308 TRP   B CG  1 
ATOM   2314 C CD1 . TRP   B 1 93  ? 27.146 15.004 -23.944 1.00 69.98  ? 308 TRP   B CD1 1 
ATOM   2315 C CD2 . TRP   B 1 93  ? 29.055 14.909 -25.128 1.00 71.69  ? 308 TRP   B CD2 1 
ATOM   2316 N NE1 . TRP   B 1 93  ? 27.313 16.211 -24.584 1.00 70.32  ? 308 TRP   B NE1 1 
ATOM   2317 C CE2 . TRP   B 1 93  ? 28.473 16.181 -25.312 1.00 70.51  ? 308 TRP   B CE2 1 
ATOM   2318 C CE3 . TRP   B 1 93  ? 30.271 14.621 -25.774 1.00 70.32  ? 308 TRP   B CE3 1 
ATOM   2319 C CZ2 . TRP   B 1 93  ? 29.065 17.168 -26.108 1.00 70.72  ? 308 TRP   B CZ2 1 
ATOM   2320 C CZ3 . TRP   B 1 93  ? 30.857 15.608 -26.571 1.00 69.44  ? 308 TRP   B CZ3 1 
ATOM   2321 C CH2 . TRP   B 1 93  ? 30.251 16.862 -26.728 1.00 68.98  ? 308 TRP   B CH2 1 
ATOM   2322 N N   . SER   B 1 108 ? 23.495 19.211 -27.515 1.00 99.90  ? 323 SER   B N   1 
ATOM   2323 C CA  . SER   B 1 108 ? 22.105 19.040 -27.094 1.00 106.35 ? 323 SER   B CA  1 
ATOM   2324 C C   . SER   B 1 108 ? 21.826 19.726 -25.750 1.00 110.52 ? 323 SER   B C   1 
ATOM   2325 O O   . SER   B 1 108 ? 20.896 19.345 -25.023 1.00 105.39 ? 323 SER   B O   1 
ATOM   2326 C CB  . SER   B 1 108 ? 21.761 17.553 -27.009 1.00 107.24 ? 323 SER   B CB  1 
ATOM   2327 N N   . GLY   B 1 109 ? 22.643 20.729 -25.416 1.00 101.94 ? 324 GLY   B N   1 
ATOM   2328 C CA  . GLY   B 1 109 ? 22.512 21.408 -24.141 1.00 98.64  ? 324 GLY   B CA  1 
ATOM   2329 C C   . GLY   B 1 109 ? 23.233 20.692 -23.006 1.00 98.00  ? 324 GLY   B C   1 
ATOM   2330 O O   . GLY   B 1 109 ? 24.092 19.816 -23.214 1.00 93.63  ? 324 GLY   B O   1 
ATOM   2331 N N   . GLY   B 1 110 ? 22.866 21.084 -21.778 1.00 87.30  ? 325 GLY   B N   1 
ATOM   2332 C CA  . GLY   B 1 110 ? 23.413 20.542 -20.546 1.00 76.78  ? 325 GLY   B CA  1 
ATOM   2333 C C   . GLY   B 1 110 ? 24.262 21.570 -19.816 1.00 70.84  ? 325 GLY   B C   1 
ATOM   2334 O O   . GLY   B 1 110 ? 24.430 22.709 -20.257 1.00 71.76  ? 325 GLY   B O   1 
ATOM   2335 N N   . PHE   B 1 111 ? 24.800 21.154 -18.668 1.00 68.18  ? 326 PHE   B N   1 
ATOM   2336 C CA  . PHE   B 1 111 ? 25.724 21.995 -17.917 1.00 66.48  ? 326 PHE   B CA  1 
ATOM   2337 C C   . PHE   B 1 111 ? 27.127 21.437 -18.077 1.00 66.32  ? 326 PHE   B C   1 
ATOM   2338 O O   . PHE   B 1 111 ? 27.371 20.266 -17.774 1.00 66.02  ? 326 PHE   B O   1 
ATOM   2339 C CB  . PHE   B 1 111 ? 25.359 22.094 -16.435 1.00 64.94  ? 326 PHE   B CB  1 
ATOM   2340 C CG  . PHE   B 1 111 ? 26.457 22.673 -15.579 1.00 61.89  ? 326 PHE   B CG  1 
ATOM   2341 C CD1 . PHE   B 1 111 ? 26.675 24.047 -15.534 1.00 62.16  ? 326 PHE   B CD1 1 
ATOM   2342 C CD2 . PHE   B 1 111 ? 27.296 21.837 -14.852 1.00 63.37  ? 326 PHE   B CD2 1 
ATOM   2343 C CE1 . PHE   B 1 111 ? 27.707 24.586 -14.749 1.00 61.54  ? 326 PHE   B CE1 1 
ATOM   2344 C CE2 . PHE   B 1 111 ? 28.328 22.353 -14.084 1.00 63.33  ? 326 PHE   B CE2 1 
ATOM   2345 C CZ  . PHE   B 1 111 ? 28.535 23.730 -14.016 1.00 61.03  ? 326 PHE   B CZ  1 
ATOM   2346 N N   . TYR   B 1 112 ? 28.032 22.272 -18.583 1.00 61.92  ? 327 TYR   B N   1 
ATOM   2347 C CA  . TYR   B 1 112 ? 29.424 21.921 -18.817 1.00 64.81  ? 327 TYR   B CA  1 
ATOM   2348 C C   . TYR   B 1 112 ? 30.273 22.520 -17.714 1.00 57.80  ? 327 TYR   B C   1 
ATOM   2349 O O   . TYR   B 1 112 ? 30.218 23.729 -17.479 1.00 54.24  ? 327 TYR   B O   1 
ATOM   2350 C CB  . TYR   B 1 112 ? 29.903 22.438 -20.177 1.00 63.78  ? 327 TYR   B CB  1 
ATOM   2351 C CG  . TYR   B 1 112 ? 29.258 21.708 -21.327 1.00 64.60  ? 327 TYR   B CG  1 
ATOM   2352 C CD1 . TYR   B 1 112 ? 27.916 21.878 -21.606 1.00 66.55  ? 327 TYR   B CD1 1 
ATOM   2353 C CD2 . TYR   B 1 112 ? 29.977 20.808 -22.098 1.00 64.10  ? 327 TYR   B CD2 1 
ATOM   2354 C CE1 . TYR   B 1 112 ? 27.310 21.205 -22.636 1.00 69.04  ? 327 TYR   B CE1 1 
ATOM   2355 C CE2 . TYR   B 1 112 ? 29.373 20.126 -23.137 1.00 66.19  ? 327 TYR   B CE2 1 
ATOM   2356 C CZ  . TYR   B 1 112 ? 28.034 20.331 -23.389 1.00 67.99  ? 327 TYR   B CZ  1 
ATOM   2357 O OH  . TYR   B 1 112 ? 27.394 19.667 -24.398 1.00 72.35  ? 327 TYR   B OH  1 
ATOM   2358 N N   . GLY   B 1 113 ? 31.064 21.684 -17.046 1.00 60.87  ? 328 GLY   B N   1 
ATOM   2359 C CA  . GLY   B 1 113 ? 31.734 22.112 -15.841 1.00 61.82  ? 328 GLY   B CA  1 
ATOM   2360 C C   . GLY   B 1 113 ? 33.107 21.496 -15.694 1.00 60.85  ? 328 GLY   B C   1 
ATOM   2361 O O   . GLY   B 1 113 ? 33.424 20.437 -16.255 1.00 57.44  ? 328 GLY   B O   1 
ATOM   2362 N N   . VAL   B 1 114 ? 33.911 22.181 -14.881 1.00 56.49  ? 329 VAL   B N   1 
ATOM   2363 C CA  . VAL   B 1 114 ? 35.279 21.793 -14.559 1.00 60.20  ? 329 VAL   B CA  1 
ATOM   2364 C C   . VAL   B 1 114 ? 35.440 21.873 -13.044 1.00 56.47  ? 329 VAL   B C   1 
ATOM   2365 O O   . VAL   B 1 114 ? 35.089 22.889 -12.434 1.00 51.76  ? 329 VAL   B O   1 
ATOM   2366 C CB  . VAL   B 1 114 ? 36.302 22.707 -15.267 1.00 56.72  ? 329 VAL   B CB  1 
ATOM   2367 C CG1 . VAL   B 1 114 ? 37.720 22.279 -14.960 1.00 57.64  ? 329 VAL   B CG1 1 
ATOM   2368 C CG2 . VAL   B 1 114 ? 36.052 22.718 -16.769 1.00 59.58  ? 329 VAL   B CG2 1 
ATOM   2369 N N   . SER   B 1 115 ? 35.951 20.807 -12.437 1.00 60.42  ? 330 SER   B N   1 
ATOM   2370 C CA  . SER   B 1 115 ? 36.184 20.752 -10.998 1.00 60.47  ? 330 SER   B CA  1 
ATOM   2371 C C   . SER   B 1 115 ? 37.650 20.457 -10.741 1.00 59.11  ? 330 SER   B C   1 
ATOM   2372 O O   . SER   B 1 115 ? 38.243 19.582 -11.394 1.00 57.89  ? 330 SER   B O   1 
ATOM   2373 C CB  . SER   B 1 115 ? 35.324 19.687 -10.315 1.00 58.72  ? 330 SER   B CB  1 
ATOM   2374 O OG  . SER   B 1 115 ? 33.942 19.970 -10.438 1.00 54.62  ? 330 SER   B OG  1 
ATOM   2375 N N   . SER   B 1 116 ? 38.227 21.192 -9.791  1.00 53.34  ? 331 SER   B N   1 
ATOM   2376 C CA  . SER   B 1 116 ? 39.609 20.988 -9.397  1.00 58.53  ? 331 SER   B CA  1 
ATOM   2377 C C   . SER   B 1 116 ? 39.692 20.900 -7.882  1.00 62.12  ? 331 SER   B C   1 
ATOM   2378 O O   . SER   B 1 116 ? 38.941 21.561 -7.157  1.00 59.03  ? 331 SER   B O   1 
ATOM   2379 C CB  . SER   B 1 116 ? 40.497 22.118 -9.878  1.00 59.47  ? 331 SER   B CB  1 
ATOM   2380 O OG  . SER   B 1 116 ? 40.552 22.163 -11.291 1.00 63.34  ? 331 SER   B OG  1 
ATOM   2381 N N   . GLN   B 1 117 ? 40.613 20.090 -7.391  1.00 61.22  ? 332 GLN   B N   1 
ATOM   2382 C CA  . GLN   B 1 117 ? 40.814 20.046 -5.953  1.00 64.20  ? 332 GLN   B CA  1 
ATOM   2383 C C   . GLN   B 1 117 ? 42.292 19.861 -5.698  1.00 63.91  ? 332 GLN   B C   1 
ATOM   2384 O O   . GLN   B 1 117 ? 42.906 18.952 -6.258  1.00 65.88  ? 332 GLN   B O   1 
ATOM   2385 C CB  . GLN   B 1 117 ? 40.000 18.930 -5.284  1.00 63.49  ? 332 GLN   B CB  1 
ATOM   2386 C CG  . GLN   B 1 117 ? 40.208 18.868 -3.757  1.00 66.23  ? 332 GLN   B CG  1 
ATOM   2387 C CD  . GLN   B 1 117 ? 39.056 18.227 -3.040  1.00 66.04  ? 332 GLN   B CD  1 
ATOM   2388 O OE1 . GLN   B 1 117 ? 37.961 18.100 -3.585  1.00 64.09  ? 332 GLN   B OE1 1 
ATOM   2389 N NE2 . GLN   B 1 117 ? 39.292 17.810 -1.804  1.00 71.57  ? 332 GLN   B NE2 1 
ATOM   2390 N N   . TYR   B 1 118 ? 42.870 20.744 -4.901  1.00 63.86  ? 333 TYR   B N   1 
ATOM   2391 C CA  . TYR   B 1 118 ? 44.260 20.617 -4.505  1.00 67.68  ? 333 TYR   B CA  1 
ATOM   2392 C C   . TYR   B 1 118 ? 44.341 20.473 -2.995  1.00 68.52  ? 333 TYR   B C   1 
ATOM   2393 O O   . TYR   B 1 118 ? 43.405 20.813 -2.271  1.00 68.06  ? 333 TYR   B O   1 
ATOM   2394 C CB  . TYR   B 1 118 ? 45.087 21.825 -4.960  1.00 67.67  ? 333 TYR   B CB  1 
ATOM   2395 C CG  . TYR   B 1 118 ? 44.994 22.149 -6.430  1.00 66.11  ? 333 TYR   B CG  1 
ATOM   2396 C CD1 . TYR   B 1 118 ? 43.997 22.986 -6.921  1.00 64.65  ? 333 TYR   B CD1 1 
ATOM   2397 C CD2 . TYR   B 1 118 ? 45.929 21.648 -7.329  1.00 65.54  ? 333 TYR   B CD2 1 
ATOM   2398 C CE1 . TYR   B 1 118 ? 43.938 23.303 -8.287  1.00 64.71  ? 333 TYR   B CE1 1 
ATOM   2399 C CE2 . TYR   B 1 118 ? 45.873 21.960 -8.671  1.00 64.42  ? 333 TYR   B CE2 1 
ATOM   2400 C CZ  . TYR   B 1 118 ? 44.878 22.779 -9.152  1.00 64.43  ? 333 TYR   B CZ  1 
ATOM   2401 O OH  . TYR   B 1 118 ? 44.834 23.076 -10.506 1.00 64.19  ? 333 TYR   B OH  1 
ATOM   2402 N N   . GLU   B 1 119 ? 45.479 19.980 -2.525  1.00 68.75  ? 334 GLU   B N   1 
ATOM   2403 C CA  . GLU   B 1 119 ? 45.697 19.788 -1.099  1.00 72.92  ? 334 GLU   B CA  1 
ATOM   2404 C C   . GLU   B 1 119 ? 47.117 20.180 -0.740  1.00 74.39  ? 334 GLU   B C   1 
ATOM   2405 O O   . GLU   B 1 119 ? 48.062 19.822 -1.443  1.00 72.76  ? 334 GLU   B O   1 
ATOM   2406 C CB  . GLU   B 1 119 ? 45.463 18.340 -0.682  1.00 74.02  ? 334 GLU   B CB  1 
ATOM   2407 C CG  . GLU   B 1 119 ? 44.066 18.120 -0.172  1.00 75.16  ? 334 GLU   B CG  1 
ATOM   2408 C CD  . GLU   B 1 119 ? 43.791 16.686 0.231   1.00 77.56  ? 334 GLU   B CD  1 
ATOM   2409 O OE1 . GLU   B 1 119 ? 44.637 16.102 0.958   1.00 79.24  ? 334 GLU   B OE1 1 
ATOM   2410 O OE2 . GLU   B 1 119 ? 42.710 16.167 -0.143  1.00 76.35  ? 334 GLU   B OE2 1 
ATOM   2411 N N   . SER   B 1 120 ? 47.272 20.887 0.370   1.00 77.30  ? 335 SER   B N   1 
ATOM   2412 C CA  . SER   B 1 120 ? 48.597 21.271 0.813   1.00 78.44  ? 335 SER   B CA  1 
ATOM   2413 C C   . SER   B 1 120 ? 48.700 21.149 2.317   1.00 81.70  ? 335 SER   B C   1 
ATOM   2414 O O   . SER   B 1 120 ? 47.704 21.059 3.036   1.00 81.14  ? 335 SER   B O   1 
ATOM   2415 C CB  . SER   B 1 120 ? 48.949 22.701 0.417   1.00 79.56  ? 335 SER   B CB  1 
ATOM   2416 O OG  . SER   B 1 120 ? 50.307 22.954 0.743   1.00 81.72  ? 335 SER   B OG  1 
ATOM   2417 N N   . LEU   B 1 121 ? 49.935 21.178 2.787   1.00 78.03  ? 336 LEU   B N   1 
ATOM   2418 C CA  . LEU   B 1 121 ? 50.219 21.221 4.204   1.00 78.01  ? 336 LEU   B CA  1 
ATOM   2419 C C   . LEU   B 1 121 ? 50.509 22.628 4.702   1.00 79.13  ? 336 LEU   B C   1 
ATOM   2420 O O   . LEU   B 1 121 ? 50.509 22.849 5.915   1.00 79.13  ? 336 LEU   B O   1 
ATOM   2421 C CB  . LEU   B 1 121 ? 51.401 20.307 4.520   1.00 76.89  ? 336 LEU   B CB  1 
ATOM   2422 C CG  . LEU   B 1 121 ? 51.058 18.841 4.733   1.00 78.54  ? 336 LEU   B CG  1 
ATOM   2423 C CD1 . LEU   B 1 121 ? 52.322 18.054 4.504   1.00 78.56  ? 336 LEU   B CD1 1 
ATOM   2424 C CD2 . LEU   B 1 121 ? 50.525 18.602 6.157   1.00 79.32  ? 336 LEU   B CD2 1 
ATOM   2425 N N   . GLU   B 1 122 ? 50.759 23.580 3.808   1.00 79.87  ? 337 GLU   B N   1 
ATOM   2426 C CA  . GLU   B 1 122 ? 50.956 24.969 4.193   1.00 80.42  ? 337 GLU   B CA  1 
ATOM   2427 C C   . GLU   B 1 122 ? 49.757 25.777 3.730   1.00 81.01  ? 337 GLU   B C   1 
ATOM   2428 O O   . GLU   B 1 122 ? 49.221 25.536 2.643   1.00 79.07  ? 337 GLU   B O   1 
ATOM   2429 C CB  . GLU   B 1 122 ? 52.248 25.531 3.599   1.00 81.12  ? 337 GLU   B CB  1 
ATOM   2430 C CG  . GLU   B 1 122 ? 52.385 25.098 2.160   1.00 87.68  ? 337 GLU   B CG  1 
ATOM   2431 C CD  . GLU   B 1 122 ? 53.814 24.848 1.753   1.00 88.36  ? 337 GLU   B CD  1 
ATOM   2432 O OE1 . GLU   B 1 122 ? 54.441 23.941 2.357   1.00 89.36  ? 337 GLU   B OE1 1 
ATOM   2433 O OE2 . GLU   B 1 122 ? 54.274 25.501 0.783   1.00 85.46  ? 337 GLU   B OE2 1 
ATOM   2434 N N   . HIS   B 1 123 ? 49.316 26.699 4.589   1.00 78.19  ? 338 HIS   B N   1 
ATOM   2435 C CA  . HIS   B 1 123 ? 48.195 27.578 4.276   1.00 77.79  ? 338 HIS   B CA  1 
ATOM   2436 C C   . HIS   B 1 123 ? 48.625 28.585 3.217   1.00 76.97  ? 338 HIS   B C   1 
ATOM   2437 O O   . HIS   B 1 123 ? 49.517 29.411 3.463   1.00 77.29  ? 338 HIS   B O   1 
ATOM   2438 C CB  . HIS   B 1 123 ? 47.740 28.327 5.527   1.00 77.42  ? 338 HIS   B CB  1 
ATOM   2439 C CG  . HIS   B 1 123 ? 46.505 29.154 5.328   1.00 77.58  ? 338 HIS   B CG  1 
ATOM   2440 N ND1 . HIS   B 1 123 ? 45.280 28.812 5.861   1.00 78.55  ? 338 HIS   B ND1 1 
ATOM   2441 C CD2 . HIS   B 1 123 ? 46.288 30.256 4.568   1.00 78.15  ? 338 HIS   B CD2 1 
ATOM   2442 C CE1 . HIS   B 1 123 ? 44.380 29.717 5.512   1.00 78.10  ? 338 HIS   B CE1 1 
ATOM   2443 N NE2 . HIS   B 1 123 ? 44.963 30.595 4.713   1.00 79.35  ? 338 HIS   B NE2 1 
ATOM   2444 N N   . MET   B 1 124 ? 48.005 28.520 2.043   1.00 77.78  ? 339 MET   B N   1 
ATOM   2445 C CA  . MET   B 1 124 ? 48.302 29.453 0.969   1.00 77.50  ? 339 MET   B CA  1 
ATOM   2446 C C   . MET   B 1 124 ? 47.004 29.985 0.391   1.00 76.24  ? 339 MET   B C   1 
ATOM   2447 O O   . MET   B 1 124 ? 45.907 29.489 0.679   1.00 74.28  ? 339 MET   B O   1 
ATOM   2448 C CB  . MET   B 1 124 ? 49.101 28.818 -0.169  1.00 76.98  ? 339 MET   B CB  1 
ATOM   2449 C CG  . MET   B 1 124 ? 50.526 28.488 0.148   1.00 79.20  ? 339 MET   B CG  1 
ATOM   2450 S SD  . MET   B 1 124 ? 51.171 27.306 -1.071  1.00 81.16  ? 339 MET   B SD  1 
ATOM   2451 C CE  . MET   B 1 124 ? 49.816 26.135 -1.229  1.00 78.06  ? 339 MET   B CE  1 
ATOM   2452 N N   . THR   B 1 125 ? 47.147 31.004 -0.442  1.00 76.18  ? 340 THR   B N   1 
ATOM   2453 C CA  . THR   B 1 125 ? 46.098 31.387 -1.366  1.00 77.58  ? 340 THR   B CA  1 
ATOM   2454 C C   . THR   B 1 125 ? 46.616 31.114 -2.765  1.00 77.13  ? 340 THR   B C   1 
ATOM   2455 O O   . THR   B 1 125 ? 47.768 31.438 -3.078  1.00 77.54  ? 340 THR   B O   1 
ATOM   2456 C CB  . THR   B 1 125 ? 45.710 32.850 -1.216  1.00 79.26  ? 340 THR   B CB  1 
ATOM   2457 O OG1 . THR   B 1 125 ? 44.817 32.985 -0.114  1.00 79.70  ? 340 THR   B OG1 1 
ATOM   2458 C CG2 . THR   B 1 125 ? 44.992 33.322 -2.468  1.00 79.34  ? 340 THR   B CG2 1 
ATOM   2459 N N   . LEU   B 1 126 ? 45.776 30.502 -3.594  1.00 76.75  ? 341 LEU   B N   1 
ATOM   2460 C CA  . LEU   B 1 126 ? 46.185 29.984 -4.890  1.00 75.62  ? 341 LEU   B CA  1 
ATOM   2461 C C   . LEU   B 1 126 ? 45.539 30.779 -6.015  1.00 74.91  ? 341 LEU   B C   1 
ATOM   2462 O O   . LEU   B 1 126 ? 44.386 31.215 -5.912  1.00 71.65  ? 341 LEU   B O   1 
ATOM   2463 C CB  . LEU   B 1 126 ? 45.817 28.507 -5.019  1.00 73.19  ? 341 LEU   B CB  1 
ATOM   2464 C CG  . LEU   B 1 126 ? 46.476 27.494 -4.072  1.00 73.34  ? 341 LEU   B CG  1 
ATOM   2465 C CD1 . LEU   B 1 126 ? 46.295 26.071 -4.599  1.00 70.99  ? 341 LEU   B CD1 1 
ATOM   2466 C CD2 . LEU   B 1 126 ? 47.947 27.817 -3.837  1.00 74.75  ? 341 LEU   B CD2 1 
ATOM   2467 N N   . THR   B 1 127 ? 46.311 31.010 -7.064  1.00 73.93  ? 342 THR   B N   1 
ATOM   2468 C CA  . THR   B 1 127 ? 45.802 31.478 -8.343  1.00 74.46  ? 342 THR   B CA  1 
ATOM   2469 C C   . THR   B 1 127 ? 45.952 30.341 -9.341  1.00 73.38  ? 342 THR   B C   1 
ATOM   2470 O O   . THR   B 1 127 ? 47.033 29.757 -9.457  1.00 69.86  ? 342 THR   B O   1 
ATOM   2471 C CB  . THR   B 1 127 ? 46.557 32.728 -8.826  1.00 74.99  ? 342 THR   B CB  1 
ATOM   2472 O OG1 . THR   B 1 127 ? 46.725 33.643 -7.740  1.00 76.16  ? 342 THR   B OG1 1 
ATOM   2473 C CG2 . THR   B 1 127 ? 45.805 33.436 -9.961  1.00 72.90  ? 342 THR   B CG2 1 
ATOM   2474 N N   . CYS   B 1 128 ? 44.864 29.994 -10.016 1.00 71.73  ? 343 CYS   B N   1 
ATOM   2475 C CA  A CYS   B 1 128 ? 44.882 28.994 -11.067 0.47 69.18  ? 343 CYS   B CA  1 
ATOM   2476 C CA  B CYS   B 1 128 ? 44.894 28.995 -11.077 0.53 67.81  ? 343 CYS   B CA  1 
ATOM   2477 C C   . CYS   B 1 128 ? 44.569 29.687 -12.389 1.00 68.28  ? 343 CYS   B C   1 
ATOM   2478 O O   . CYS   B 1 128 ? 43.475 30.233 -12.559 1.00 68.15  ? 343 CYS   B O   1 
ATOM   2479 C CB  A CYS   B 1 128 ? 43.878 27.890 -10.750 0.47 66.84  ? 343 CYS   B CB  1 
ATOM   2480 C CB  B CYS   B 1 128 ? 43.917 27.842 -10.846 0.53 70.58  ? 343 CYS   B CB  1 
ATOM   2481 S SG  A CYS   B 1 128 ? 43.883 27.435 -8.988  0.47 68.88  ? 343 CYS   B SG  1 
ATOM   2482 S SG  B CYS   B 1 128 ? 44.005 26.589 -12.204 0.53 67.94  ? 343 CYS   B SG  1 
ATOM   2483 N N   . SER   B 1 129 ? 45.527 29.676 -13.297 1.00 68.76  ? 344 SER   B N   1 
ATOM   2484 C CA  . SER   B 1 129 ? 45.393 30.268 -14.616 1.00 66.91  ? 344 SER   B CA  1 
ATOM   2485 C C   . SER   B 1 129 ? 45.333 29.142 -15.637 1.00 65.61  ? 344 SER   B C   1 
ATOM   2486 O O   . SER   B 1 129 ? 46.202 28.266 -15.647 1.00 65.07  ? 344 SER   B O   1 
ATOM   2487 C CB  . SER   B 1 129 ? 46.571 31.187 -14.885 1.00 67.16  ? 344 SER   B CB  1 
ATOM   2488 O OG  . SER   B 1 129 ? 46.896 31.132 -16.244 1.00 70.99  ? 344 SER   B OG  1 
ATOM   2489 N N   . SER   B 1 130 ? 44.299 29.137 -16.463 1.00 65.41  ? 345 SER   B N   1 
ATOM   2490 C CA  . SER   B 1 130 ? 44.142 28.128 -17.498 1.00 65.74  ? 345 SER   B CA  1 
ATOM   2491 C C   . SER   B 1 130 ? 44.239 28.836 -18.841 1.00 69.47  ? 345 SER   B C   1 
ATOM   2492 O O   . SER   B 1 130 ? 43.421 29.711 -19.137 1.00 68.76  ? 345 SER   B O   1 
ATOM   2493 C CB  . SER   B 1 130 ? 42.809 27.404 -17.365 1.00 64.64  ? 345 SER   B CB  1 
ATOM   2494 O OG  . SER   B 1 130 ? 42.769 26.607 -16.183 1.00 65.89  ? 345 SER   B OG  1 
ATOM   2495 N N   . LYS   B 1 131 ? 45.259 28.494 -19.625 1.00 67.87  ? 346 LYS   B N   1 
ATOM   2496 C CA  . LYS   B 1 131 ? 45.504 29.087 -20.945 1.00 72.61  ? 346 LYS   B CA  1 
ATOM   2497 C C   . LYS   B 1 131 ? 45.178 28.052 -22.019 1.00 70.95  ? 346 LYS   B C   1 
ATOM   2498 O O   . LYS   B 1 131 ? 45.877 27.043 -22.147 1.00 67.60  ? 346 LYS   B O   1 
ATOM   2499 C CB  . LYS   B 1 131 ? 46.954 29.535 -21.078 1.00 74.06  ? 346 LYS   B CB  1 
ATOM   2500 C CG  . LYS   B 1 131 ? 47.390 30.669 -20.195 1.00 78.54  ? 346 LYS   B CG  1 
ATOM   2501 C CD  . LYS   B 1 131 ? 48.572 31.365 -20.833 1.00 86.10  ? 346 LYS   B CD  1 
ATOM   2502 C CE  . LYS   B 1 131 ? 49.639 31.676 -19.810 1.00 93.02  ? 346 LYS   B CE  1 
ATOM   2503 N NZ  . LYS   B 1 131 ? 49.052 32.369 -18.616 1.00 89.05  ? 346 LYS   B NZ  1 
ATOM   2504 N N   . VAL   B 1 132 ? 44.107 28.280 -22.766 1.00 68.71  ? 347 VAL   B N   1 
ATOM   2505 C CA  . VAL   B 1 132 ? 43.730 27.397 -23.863 1.00 71.55  ? 347 VAL   B CA  1 
ATOM   2506 C C   . VAL   B 1 132 ? 44.378 27.924 -25.132 1.00 73.37  ? 347 VAL   B C   1 
ATOM   2507 O O   . VAL   B 1 132 ? 44.176 29.087 -25.509 1.00 68.53  ? 347 VAL   B O   1 
ATOM   2508 C CB  . VAL   B 1 132 ? 42.207 27.311 -24.013 1.00 69.16  ? 347 VAL   B CB  1 
ATOM   2509 C CG1 . VAL   B 1 132 ? 41.852 26.527 -25.250 1.00 67.29  ? 347 VAL   B CG1 1 
ATOM   2510 C CG2 . VAL   B 1 132 ? 41.593 26.685 -22.770 1.00 67.98  ? 347 VAL   B CG2 1 
ATOM   2511 N N   . CYS   B 1 133 ? 45.160 27.071 -25.785 1.00 73.52  ? 348 CYS   B N   1 
ATOM   2512 C CA  . CYS   B 1 133 ? 45.987 27.452 -26.919 1.00 73.05  ? 348 CYS   B CA  1 
ATOM   2513 C C   . CYS   B 1 133 ? 45.570 26.681 -28.161 1.00 72.52  ? 348 CYS   B C   1 
ATOM   2514 O O   . CYS   B 1 133 ? 45.313 25.482 -28.102 1.00 67.15  ? 348 CYS   B O   1 
ATOM   2515 C CB  . CYS   B 1 133 ? 47.465 27.184 -26.634 1.00 75.73  ? 348 CYS   B CB  1 
ATOM   2516 S SG  . CYS   B 1 133 ? 48.136 28.118 -25.252 1.00 79.19  ? 348 CYS   B SG  1 
ATOM   2517 N N   . SER   B 1 134 ? 45.543 27.365 -29.297 1.00 75.42  ? 349 SER   B N   1 
ATOM   2518 C CA  . SER   B 1 134 ? 45.185 26.742 -30.562 1.00 71.96  ? 349 SER   B CA  1 
ATOM   2519 C C   . SER   B 1 134 ? 46.302 27.059 -31.543 1.00 75.02  ? 349 SER   B C   1 
ATOM   2520 O O   . SER   B 1 134 ? 46.526 28.233 -31.872 1.00 76.18  ? 349 SER   B O   1 
ATOM   2521 C CB  . SER   B 1 134 ? 43.836 27.257 -31.051 1.00 71.93  ? 349 SER   B CB  1 
ATOM   2522 O OG  . SER   B 1 134 ? 43.649 26.915 -32.408 1.00 72.14  ? 349 SER   B OG  1 
ATOM   2523 N N   . PHE   B 1 135 ? 47.002 26.027 -32.023 1.00 73.05  ? 350 PHE   B N   1 
ATOM   2524 C CA  . PHE   B 1 135 ? 48.185 26.265 -32.852 1.00 75.08  ? 350 PHE   B CA  1 
ATOM   2525 C C   . PHE   B 1 135 ? 49.246 27.027 -32.054 1.00 80.11  ? 350 PHE   B C   1 
ATOM   2526 O O   . PHE   B 1 135 ? 49.943 27.897 -32.580 1.00 80.19  ? 350 PHE   B O   1 
ATOM   2527 C CB  . PHE   B 1 135 ? 47.780 27.028 -34.124 1.00 73.99  ? 350 PHE   B CB  1 
ATOM   2528 C CG  . PHE   B 1 135 ? 47.137 26.161 -35.185 1.00 72.07  ? 350 PHE   B CG  1 
ATOM   2529 C CD1 . PHE   B 1 135 ? 47.904 25.433 -36.086 1.00 72.51  ? 350 PHE   B CD1 1 
ATOM   2530 C CD2 . PHE   B 1 135 ? 45.753 25.918 -35.134 1.00 74.01  ? 350 PHE   B CD2 1 
ATOM   2531 C CE1 . PHE   B 1 135 ? 47.278 24.577 -37.020 1.00 69.16  ? 350 PHE   B CE1 1 
ATOM   2532 C CE2 . PHE   B 1 135 ? 45.129 25.071 -36.048 1.00 69.28  ? 350 PHE   B CE2 1 
ATOM   2533 C CZ  . PHE   B 1 135 ? 45.888 24.384 -36.985 1.00 67.14  ? 350 PHE   B CZ  1 
ATOM   2534 N N   . GLY   B 1 136 ? 49.356 26.713 -30.762 1.00 90.07  ? 351 GLY   B N   1 
ATOM   2535 C CA  . GLY   B 1 136 ? 50.313 27.391 -29.905 1.00 91.54  ? 351 GLY   B CA  1 
ATOM   2536 C C   . GLY   B 1 136 ? 50.065 28.870 -29.669 1.00 93.78  ? 351 GLY   B C   1 
ATOM   2537 O O   . GLY   B 1 136 ? 50.994 29.593 -29.281 1.00 97.95  ? 351 GLY   B O   1 
ATOM   2538 N N   . LYS   B 1 137 ? 48.839 29.341 -29.893 1.00 84.10  ? 352 LYS   B N   1 
ATOM   2539 C CA  . LYS   B 1 137 ? 48.459 30.739 -29.722 1.00 82.05  ? 352 LYS   B CA  1 
ATOM   2540 C C   . LYS   B 1 137 ? 47.359 30.786 -28.673 1.00 78.71  ? 352 LYS   B C   1 
ATOM   2541 O O   . LYS   B 1 137 ? 46.336 30.105 -28.817 1.00 75.95  ? 352 LYS   B O   1 
ATOM   2542 C CB  . LYS   B 1 137 ? 47.974 31.334 -31.046 1.00 80.77  ? 352 LYS   B CB  1 
ATOM   2543 C CG  . LYS   B 1 137 ? 49.088 31.852 -31.978 1.00 83.77  ? 352 LYS   B CG  1 
ATOM   2544 C CD  . LYS   B 1 137 ? 48.798 31.546 -33.455 1.00 85.31  ? 352 LYS   B CD  1 
ATOM   2545 C CE  . LYS   B 1 137 ? 48.872 32.766 -34.450 1.00 81.51  ? 352 LYS   B CE  1 
ATOM   2546 N NZ  . LYS   B 1 137 ? 49.866 33.860 -34.211 1.00 79.92  ? 352 LYS   B NZ  1 
ATOM   2547 N N   . GLN   B 1 138 ? 47.581 31.544 -27.599 1.00 76.86  ? 353 GLN   B N   1 
ATOM   2548 C CA  . GLN   B 1 138 ? 46.572 31.623 -26.545 1.00 73.73  ? 353 GLN   B CA  1 
ATOM   2549 C C   . GLN   B 1 138 ? 45.272 32.154 -27.127 1.00 74.01  ? 353 GLN   B C   1 
ATOM   2550 O O   . GLN   B 1 138 ? 45.271 33.167 -27.823 1.00 74.22  ? 353 GLN   B O   1 
ATOM   2551 C CB  . GLN   B 1 138 ? 47.042 32.529 -25.404 1.00 74.61  ? 353 GLN   B CB  1 
ATOM   2552 C CG  . GLN   B 1 138 ? 46.067 32.543 -24.232 1.00 74.79  ? 353 GLN   B CG  1 
ATOM   2553 C CD  . GLN   B 1 138 ? 46.407 33.581 -23.159 1.00 76.83  ? 353 GLN   B CD  1 
ATOM   2554 O OE1 . GLN   B 1 138 ? 47.413 33.456 -22.460 1.00 80.91  ? 353 GLN   B OE1 1 
ATOM   2555 N NE2 . GLN   B 1 138 ? 45.560 34.601 -23.020 1.00 75.87  ? 353 GLN   B NE2 1 
ATOM   2556 N N   . VAL   B 1 139 ? 44.157 31.480 -26.859 1.00 71.50  ? 354 VAL   B N   1 
ATOM   2557 C CA  . VAL   B 1 139 ? 42.902 31.981 -27.420 1.00 72.67  ? 354 VAL   B CA  1 
ATOM   2558 C C   . VAL   B 1 139 ? 41.941 32.351 -26.306 1.00 71.63  ? 354 VAL   B C   1 
ATOM   2559 O O   . VAL   B 1 139 ? 41.099 33.236 -26.469 1.00 73.05  ? 354 VAL   B O   1 
ATOM   2560 C CB  . VAL   B 1 139 ? 42.263 30.963 -28.379 1.00 73.28  ? 354 VAL   B CB  1 
ATOM   2561 C CG1 . VAL   B 1 139 ? 43.273 30.556 -29.448 1.00 74.11  ? 354 VAL   B CG1 1 
ATOM   2562 C CG2 . VAL   B 1 139 ? 41.789 29.765 -27.631 1.00 70.85  ? 354 VAL   B CG2 1 
ATOM   2563 N N   . VAL   B 1 140 ? 42.074 31.680 -25.169 1.00 71.23  ? 355 VAL   B N   1 
ATOM   2564 C CA  . VAL   B 1 140 ? 41.280 31.945 -23.979 1.00 70.72  ? 355 VAL   B CA  1 
ATOM   2565 C C   . VAL   B 1 140 ? 42.160 31.727 -22.764 1.00 70.28  ? 355 VAL   B C   1 
ATOM   2566 O O   . VAL   B 1 140 ? 42.938 30.770 -22.721 1.00 69.47  ? 355 VAL   B O   1 
ATOM   2567 C CB  . VAL   B 1 140 ? 40.029 31.049 -23.897 1.00 70.17  ? 355 VAL   B CB  1 
ATOM   2568 C CG1 . VAL   B 1 140 ? 39.177 31.499 -22.726 1.00 73.17  ? 355 VAL   B CG1 1 
ATOM   2569 C CG2 . VAL   B 1 140 ? 39.221 31.248 -25.154 1.00 71.77  ? 355 VAL   B CG2 1 
ATOM   2570 N N   . GLU   B 1 141 ? 42.043 32.631 -21.788 1.00 70.30  ? 356 GLU   B N   1 
ATOM   2571 C CA  . GLU   B 1 141 ? 42.646 32.461 -20.474 1.00 72.31  ? 356 GLU   B CA  1 
ATOM   2572 C C   . GLU   B 1 141 ? 41.573 32.629 -19.408 1.00 72.03  ? 356 GLU   B C   1 
ATOM   2573 O O   . GLU   B 1 141 ? 40.773 33.569 -19.473 1.00 72.04  ? 356 GLU   B O   1 
ATOM   2574 C CB  . GLU   B 1 141 ? 43.772 33.467 -20.241 1.00 73.36  ? 356 GLU   B CB  1 
ATOM   2575 C CG  . GLU   B 1 141 ? 44.472 33.250 -18.940 1.00 73.45  ? 356 GLU   B CG  1 
ATOM   2576 C CD  . GLU   B 1 141 ? 45.635 34.174 -18.761 1.00 76.55  ? 356 GLU   B CD  1 
ATOM   2577 O OE1 . GLU   B 1 141 ? 45.580 35.331 -19.248 1.00 79.30  ? 356 GLU   B OE1 1 
ATOM   2578 O OE2 . GLU   B 1 141 ? 46.614 33.736 -18.127 1.00 77.63  ? 356 GLU   B OE2 1 
ATOM   2579 N N   . LYS   B 1 142 ? 41.561 31.730 -18.426 1.00 69.77  ? 357 LYS   B N   1 
ATOM   2580 C CA  . LYS   B 1 142 ? 40.717 31.860 -17.240 1.00 69.18  ? 357 LYS   B CA  1 
ATOM   2581 C C   . LYS   B 1 142 ? 41.593 31.852 -15.994 1.00 70.26  ? 357 LYS   B C   1 
ATOM   2582 O O   . LYS   B 1 142 ? 42.454 30.974 -15.846 1.00 69.05  ? 357 LYS   B O   1 
ATOM   2583 C CB  . LYS   B 1 142 ? 39.673 30.735 -17.167 1.00 69.00  ? 357 LYS   B CB  1 
ATOM   2584 C CG  . LYS   B 1 142 ? 38.974 30.627 -15.799 1.00 72.18  ? 357 LYS   B CG  1 
ATOM   2585 C CD  . LYS   B 1 142 ? 37.466 30.830 -15.950 1.00 72.63  ? 357 LYS   B CD  1 
ATOM   2586 C CE  . LYS   B 1 142 ? 36.744 30.831 -14.606 1.00 75.40  ? 357 LYS   B CE  1 
ATOM   2587 N NZ  . LYS   B 1 142 ? 35.266 31.089 -14.712 1.00 77.50  ? 357 LYS   B NZ  1 
ATOM   2588 N N   . VAL   B 1 143 ? 41.365 32.811 -15.096 1.00 69.51  ? 358 VAL   B N   1 
ATOM   2589 C CA  . VAL   B 1 143 ? 42.170 32.948 -13.887 1.00 71.49  ? 358 VAL   B CA  1 
ATOM   2590 C C   . VAL   B 1 143 ? 41.234 32.938 -12.686 1.00 71.73  ? 358 VAL   B C   1 
ATOM   2591 O O   . VAL   B 1 143 ? 40.228 33.653 -12.679 1.00 71.94  ? 358 VAL   B O   1 
ATOM   2592 C CB  . VAL   B 1 143 ? 43.012 34.237 -13.908 1.00 71.35  ? 358 VAL   B CB  1 
ATOM   2593 C CG1 . VAL   B 1 143 ? 44.067 34.211 -12.823 1.00 70.82  ? 358 VAL   B CG1 1 
ATOM   2594 C CG2 . VAL   B 1 143 ? 43.630 34.461 -15.277 1.00 70.93  ? 358 VAL   B CG2 1 
ATOM   2595 N N   . GLU   B 1 144 ? 41.559 32.130 -11.673 1.00 71.07  ? 359 GLU   B N   1 
ATOM   2596 C CA  . GLU   B 1 144 ? 40.765 32.050 -10.445 1.00 70.06  ? 359 GLU   B CA  1 
ATOM   2597 C C   . GLU   B 1 144 ? 41.699 32.008 -9.249  1.00 69.04  ? 359 GLU   B C   1 
ATOM   2598 O O   . GLU   B 1 144 ? 42.832 31.527 -9.357  1.00 70.39  ? 359 GLU   B O   1 
ATOM   2599 C CB  . GLU   B 1 144 ? 39.903 30.791 -10.411 1.00 70.18  ? 359 GLU   B CB  1 
ATOM   2600 C CG  . GLU   B 1 144 ? 38.536 30.954 -11.017 1.00 70.95  ? 359 GLU   B CG  1 
ATOM   2601 C CD  . GLU   B 1 144 ? 38.078 29.659 -11.648 1.00 76.34  ? 359 GLU   B CD  1 
ATOM   2602 O OE1 . GLU   B 1 144 ? 36.852 29.434 -11.748 1.00 79.61  ? 359 GLU   B OE1 1 
ATOM   2603 O OE2 . GLU   B 1 144 ? 38.963 28.847 -12.022 1.00 75.83  ? 359 GLU   B OE2 1 
ATOM   2604 N N   . THR   B 1 145 ? 41.220 32.504 -8.105  1.00 68.14  ? 360 THR   B N   1 
ATOM   2605 C CA  . THR   B 1 145 ? 41.924 32.355 -6.840  1.00 68.47  ? 360 THR   B CA  1 
ATOM   2606 C C   . THR   B 1 145 ? 41.045 31.592 -5.851  1.00 68.87  ? 360 THR   B C   1 
ATOM   2607 O O   . THR   B 1 145 ? 39.812 31.709 -5.859  1.00 68.43  ? 360 THR   B O   1 
ATOM   2608 C CB  . THR   B 1 145 ? 42.302 33.709 -6.227  1.00 70.57  ? 360 THR   B CB  1 
ATOM   2609 O OG1 . THR   B 1 145 ? 41.117 34.340 -5.741  1.00 75.21  ? 360 THR   B OG1 1 
ATOM   2610 C CG2 . THR   B 1 145 ? 42.933 34.627 -7.270  1.00 71.28  ? 360 THR   B CG2 1 
ATOM   2611 N N   . GLU   B 1 146 ? 41.692 30.844 -4.963  1.00 70.51  ? 361 GLU   B N   1 
ATOM   2612 C CA  . GLU   B 1 146 ? 40.995 30.041 -3.966  1.00 71.35  ? 361 GLU   B CA  1 
ATOM   2613 C C   . GLU   B 1 146 ? 41.875 29.946 -2.725  1.00 71.96  ? 361 GLU   B C   1 
ATOM   2614 O O   . GLU   B 1 146 ? 43.061 29.623 -2.836  1.00 71.64  ? 361 GLU   B O   1 
ATOM   2615 C CB  . GLU   B 1 146 ? 40.672 28.646 -4.540  1.00 69.82  ? 361 GLU   B CB  1 
ATOM   2616 C CG  . GLU   B 1 146 ? 40.143 27.622 -3.540  1.00 69.05  ? 361 GLU   B CG  1 
ATOM   2617 C CD  . GLU   B 1 146 ? 38.692 27.858 -3.196  1.00 69.80  ? 361 GLU   B CD  1 
ATOM   2618 O OE1 . GLU   B 1 146 ? 37.954 28.352 -4.078  1.00 69.34  ? 361 GLU   B OE1 1 
ATOM   2619 O OE2 . GLU   B 1 146 ? 38.292 27.557 -2.047  1.00 69.59  ? 361 GLU   B OE2 1 
ATOM   2620 N N   . ARG   B 1 147 ? 41.311 30.252 -1.557  1.00 72.40  ? 362 ARG   B N   1 
ATOM   2621 C CA  . ARG   B 1 147 ? 42.064 30.185 -0.310  1.00 73.78  ? 362 ARG   B CA  1 
ATOM   2622 C C   . ARG   B 1 147 ? 41.852 28.847 0.373   1.00 71.34  ? 362 ARG   B C   1 
ATOM   2623 O O   . ARG   B 1 147 ? 40.817 28.201 0.207   1.00 70.48  ? 362 ARG   B O   1 
ATOM   2624 C CB  . ARG   B 1 147 ? 41.677 31.303 0.659   1.00 76.64  ? 362 ARG   B CB  1 
ATOM   2625 C CG  . ARG   B 1 147 ? 41.558 32.648 0.008   1.00 78.84  ? 362 ARG   B CG  1 
ATOM   2626 C CD  . ARG   B 1 147 ? 41.223 33.747 0.988   1.00 86.14  ? 362 ARG   B CD  1 
ATOM   2627 N NE  . ARG   B 1 147 ? 40.263 33.407 2.039   1.00 92.20  ? 362 ARG   B NE  1 
ATOM   2628 C CZ  . ARG   B 1 147 ? 38.943 33.482 1.905   1.00 93.18  ? 362 ARG   B CZ  1 
ATOM   2629 N NH1 . ARG   B 1 147 ? 38.378 33.741 0.731   1.00 91.26  ? 362 ARG   B NH1 1 
ATOM   2630 N NH2 . ARG   B 1 147 ? 38.170 33.305 2.978   1.00 92.46  ? 362 ARG   B NH2 1 
ATOM   2631 N N   . ALA   B 1 148 ? 42.849 28.441 1.151   1.00 72.02  ? 363 ALA   B N   1 
ATOM   2632 C CA  . ALA   B 1 148 ? 42.813 27.120 1.751   1.00 73.13  ? 363 ALA   B CA  1 
ATOM   2633 C C   . ALA   B 1 148 ? 41.603 26.981 2.661   1.00 74.05  ? 363 ALA   B C   1 
ATOM   2634 O O   . ALA   B 1 148 ? 41.132 27.948 3.263   1.00 74.75  ? 363 ALA   B O   1 
ATOM   2635 C CB  . ALA   B 1 148 ? 44.090 26.854 2.548   1.00 75.03  ? 363 ALA   B CB  1 
ATOM   2636 N N   . GLN   B 1 149 ? 41.096 25.759 2.759   1.00 72.53  ? 364 GLN   B N   1 
ATOM   2637 C CA  . GLN   B 1 149 ? 40.180 25.386 3.830   1.00 73.26  ? 364 GLN   B CA  1 
ATOM   2638 C C   . GLN   B 1 149 ? 40.890 24.362 4.700   1.00 74.70  ? 364 GLN   B C   1 
ATOM   2639 O O   . GLN   B 1 149 ? 41.341 23.336 4.188   1.00 75.70  ? 364 GLN   B O   1 
ATOM   2640 C CB  . GLN   B 1 149 ? 38.871 24.842 3.256   1.00 72.68  ? 364 GLN   B CB  1 
ATOM   2641 C CG  . GLN   B 1 149 ? 37.842 25.937 3.035   1.00 73.68  ? 364 GLN   B CG  1 
ATOM   2642 C CD  . GLN   B 1 149 ? 36.680 25.512 2.164   1.00 73.75  ? 364 GLN   B CD  1 
ATOM   2643 O OE1 . GLN   B 1 149 ? 35.523 25.599 2.588   1.00 74.97  ? 364 GLN   B OE1 1 
ATOM   2644 N NE2 . GLN   B 1 149 ? 36.967 25.046 0.962   1.00 71.31  ? 364 GLN   B NE2 1 
ATOM   2645 N N   . LEU   B 1 150 ? 41.052 24.675 5.986   1.00 76.47  ? 365 LEU   B N   1 
ATOM   2646 C CA  . LEU   B 1 150 ? 41.632 23.748 6.957   1.00 77.84  ? 365 LEU   B CA  1 
ATOM   2647 C C   . LEU   B 1 150 ? 40.708 22.565 7.147   1.00 78.42  ? 365 LEU   B C   1 
ATOM   2648 O O   . LEU   B 1 150 ? 39.680 22.691 7.809   1.00 77.71  ? 365 LEU   B O   1 
ATOM   2649 C CB  . LEU   B 1 150 ? 41.853 24.422 8.300   1.00 77.19  ? 365 LEU   B CB  1 
ATOM   2650 C CG  . LEU   B 1 150 ? 43.287 24.522 8.800   1.00 80.30  ? 365 LEU   B CG  1 
ATOM   2651 C CD1 . LEU   B 1 150 ? 43.395 25.206 10.198  1.00 81.63  ? 365 LEU   B CD1 1 
ATOM   2652 C CD2 . LEU   B 1 150 ? 43.923 23.140 8.779   1.00 81.45  ? 365 LEU   B CD2 1 
ATOM   2653 N N   . GLU   B 1 151 ? 41.119 21.396 6.668   1.00 80.72  ? 366 GLU   B N   1 
ATOM   2654 C CA  . GLU   B 1 151 ? 40.308 20.185 6.768   1.00 80.14  ? 366 GLU   B CA  1 
ATOM   2655 C C   . GLU   B 1 151 ? 41.171 19.018 7.222   1.00 83.78  ? 366 GLU   B C   1 
ATOM   2656 O O   . GLU   B 1 151 ? 41.721 18.278 6.409   1.00 85.72  ? 366 GLU   B O   1 
ATOM   2657 C CB  . GLU   B 1 151 ? 39.646 19.913 5.440   1.00 79.00  ? 366 GLU   B CB  1 
ATOM   2658 C CG  . GLU   B 1 151 ? 38.517 20.846 5.246   1.00 76.70  ? 366 GLU   B CG  1 
ATOM   2659 C CD  . GLU   B 1 151 ? 37.507 20.312 4.285   1.00 74.57  ? 366 GLU   B CD  1 
ATOM   2660 O OE1 . GLU   B 1 151 ? 37.748 19.235 3.691   1.00 74.69  ? 366 GLU   B OE1 1 
ATOM   2661 O OE2 . GLU   B 1 151 ? 36.438 20.947 4.175   1.00 75.11  ? 366 GLU   B OE2 1 
ATOM   2662 N N   . ASP   B 1 152 ? 41.280 18.866 8.520   1.00 85.65  ? 367 ASP   B N   1 
ATOM   2663 C CA  . ASP   B 1 152 ? 41.900 17.695 9.111   1.00 91.54  ? 367 ASP   B CA  1 
ATOM   2664 C C   . ASP   B 1 152 ? 43.402 17.816 8.919   1.00 91.64  ? 367 ASP   B C   1 
ATOM   2665 O O   . ASP   B 1 152 ? 43.952 17.192 8.008   1.00 90.98  ? 367 ASP   B O   1 
ATOM   2666 C CB  . ASP   B 1 152 ? 41.308 16.421 8.479   1.00 91.19  ? 367 ASP   B CB  1 
ATOM   2667 C CG  . ASP   B 1 152 ? 42.007 15.140 8.927   1.00 100.18 ? 367 ASP   B CG  1 
ATOM   2668 O OD1 . ASP   B 1 152 ? 43.258 15.015 8.936   1.00 102.19 ? 367 ASP   B OD1 1 
ATOM   2669 O OD2 . ASP   B 1 152 ? 41.245 14.313 9.483   1.00 109.23 ? 367 ASP   B OD2 1 
ATOM   2670 N N   . GLY   B 1 153 ? 44.064 18.640 9.743   1.00 86.72  ? 368 GLY   B N   1 
ATOM   2671 C CA  . GLY   B 1 153 ? 45.499 18.873 9.615   1.00 87.17  ? 368 GLY   B CA  1 
ATOM   2672 C C   . GLY   B 1 153 ? 45.976 18.885 8.175   1.00 89.46  ? 368 GLY   B C   1 
ATOM   2673 O O   . GLY   B 1 153 ? 46.789 18.042 7.771   1.00 93.88  ? 368 GLY   B O   1 
ATOM   2674 N N   . ARG   B 1 154 ? 45.463 19.819 7.374   1.00 87.65  ? 369 ARG   B N   1 
ATOM   2675 C CA  . ARG   B 1 154 ? 45.603 19.709 5.932   1.00 84.35  ? 369 ARG   B CA  1 
ATOM   2676 C C   . ARG   B 1 154 ? 44.675 20.715 5.282   1.00 83.12  ? 369 ARG   B C   1 
ATOM   2677 O O   . ARG   B 1 154 ? 43.519 20.847 5.690   1.00 82.70  ? 369 ARG   B O   1 
ATOM   2678 C CB  . ARG   B 1 154 ? 45.281 18.282 5.489   1.00 84.92  ? 369 ARG   B CB  1 
ATOM   2679 C CG  . ARG   B 1 154 ? 45.456 17.987 4.014   1.00 81.45  ? 369 ARG   B CG  1 
ATOM   2680 C CD  . ARG   B 1 154 ? 46.321 16.735 3.798   1.00 84.49  ? 369 ARG   B CD  1 
ATOM   2681 N NE  . ARG   B 1 154 ? 47.212 16.847 2.640   1.00 86.08  ? 369 ARG   B NE  1 
ATOM   2682 C CZ  . ARG   B 1 154 ? 48.325 16.137 2.484   1.00 84.52  ? 369 ARG   B CZ  1 
ATOM   2683 N NH1 . ARG   B 1 154 ? 48.718 15.265 3.400   1.00 87.40  ? 369 ARG   B NH1 1 
ATOM   2684 N NH2 . ARG   B 1 154 ? 49.067 16.320 1.392   1.00 81.86  ? 369 ARG   B NH2 1 
ATOM   2685 N N   . PHE   B 1 155 ? 45.166 21.435 4.285   1.00 81.37  ? 370 PHE   B N   1 
ATOM   2686 C CA  . PHE   B 1 155 ? 44.415 22.488 3.616   1.00 80.47  ? 370 PHE   B CA  1 
ATOM   2687 C C   . PHE   B 1 155 ? 43.936 21.994 2.257   1.00 78.73  ? 370 PHE   B C   1 
ATOM   2688 O O   . PHE   B 1 155 ? 44.697 21.374 1.510   1.00 76.73  ? 370 PHE   B O   1 
ATOM   2689 C CB  . PHE   B 1 155 ? 45.287 23.736 3.454   1.00 81.46  ? 370 PHE   B CB  1 
ATOM   2690 C CG  . PHE   B 1 155 ? 45.801 24.289 4.753   1.00 83.25  ? 370 PHE   B CG  1 
ATOM   2691 C CD1 . PHE   B 1 155 ? 44.940 24.784 5.711   1.00 83.70  ? 370 PHE   B CD1 1 
ATOM   2692 C CD2 . PHE   B 1 155 ? 47.157 24.369 4.983   1.00 83.39  ? 370 PHE   B CD2 1 
ATOM   2693 C CE1 . PHE   B 1 155 ? 45.431 25.321 6.906   1.00 84.18  ? 370 PHE   B CE1 1 
ATOM   2694 C CE2 . PHE   B 1 155 ? 47.654 24.887 6.160   1.00 85.10  ? 370 PHE   B CE2 1 
ATOM   2695 C CZ  . PHE   B 1 155 ? 46.784 25.375 7.129   1.00 83.40  ? 370 PHE   B CZ  1 
ATOM   2696 N N   . VAL   B 1 156 ? 42.676 22.266 1.930   1.00 74.98  ? 371 VAL   B N   1 
ATOM   2697 C CA  . VAL   B 1 156 ? 42.087 21.829 0.668   1.00 73.54  ? 371 VAL   B CA  1 
ATOM   2698 C C   . VAL   B 1 156 ? 41.649 23.039 -0.141  1.00 72.95  ? 371 VAL   B C   1 
ATOM   2699 O O   . VAL   B 1 156 ? 41.116 24.011 0.407   1.00 71.35  ? 371 VAL   B O   1 
ATOM   2700 C CB  . VAL   B 1 156 ? 40.895 20.890 0.905   1.00 73.28  ? 371 VAL   B CB  1 
ATOM   2701 C CG1 . VAL   B 1 156 ? 41.301 19.785 1.839   1.00 75.56  ? 371 VAL   B CG1 1 
ATOM   2702 C CG2 . VAL   B 1 156 ? 39.780 21.668 1.531   1.00 73.40  ? 371 VAL   B CG2 1 
ATOM   2703 N N   . TYR   B 1 157 ? 41.849 22.962 -1.451  1.00 69.64  ? 372 TYR   B N   1 
ATOM   2704 C CA  . TYR   B 1 157 ? 41.518 24.041 -2.369  1.00 68.73  ? 372 TYR   B CA  1 
ATOM   2705 C C   . TYR   B 1 157 ? 40.487 23.504 -3.334  1.00 66.53  ? 372 TYR   B C   1 
ATOM   2706 O O   . TYR   B 1 157 ? 40.809 22.682 -4.192  1.00 64.76  ? 372 TYR   B O   1 
ATOM   2707 C CB  . TYR   B 1 157 ? 42.764 24.534 -3.090  1.00 68.27  ? 372 TYR   B CB  1 
ATOM   2708 C CG  . TYR   B 1 157 ? 43.865 24.922 -2.132  1.00 71.27  ? 372 TYR   B CG  1 
ATOM   2709 C CD1 . TYR   B 1 157 ? 44.562 23.958 -1.411  1.00 72.93  ? 372 TYR   B CD1 1 
ATOM   2710 C CD2 . TYR   B 1 157 ? 44.164 26.260 -1.900  1.00 72.99  ? 372 TYR   B CD2 1 
ATOM   2711 C CE1 . TYR   B 1 157 ? 45.550 24.310 -0.521  1.00 75.02  ? 372 TYR   B CE1 1 
ATOM   2712 C CE2 . TYR   B 1 157 ? 45.151 26.623 -1.014  1.00 74.17  ? 372 TYR   B CE2 1 
ATOM   2713 C CZ  . TYR   B 1 157 ? 45.842 25.646 -0.323  1.00 76.14  ? 372 TYR   B CZ  1 
ATOM   2714 O OH  . TYR   B 1 157 ? 46.827 26.012 0.575   1.00 78.67  ? 372 TYR   B OH  1 
ATOM   2715 N N   . ARG   B 1 158 ? 39.252 23.946 -3.195  1.00 65.34  ? 373 ARG   B N   1 
ATOM   2716 C CA  . ARG   B 1 158 ? 38.158 23.399 -3.978  1.00 64.06  ? 373 ARG   B CA  1 
ATOM   2717 C C   . ARG   B 1 158 ? 37.692 24.444 -4.967  1.00 61.89  ? 373 ARG   B C   1 
ATOM   2718 O O   . ARG   B 1 158 ? 37.254 25.524 -4.579  1.00 62.50  ? 373 ARG   B O   1 
ATOM   2719 C CB  . ARG   B 1 158 ? 37.000 22.952 -3.089  1.00 65.13  ? 373 ARG   B CB  1 
ATOM   2720 C CG  . ARG   B 1 158 ? 37.338 21.715 -2.278  1.00 66.92  ? 373 ARG   B CG  1 
ATOM   2721 C CD  . ARG   B 1 158 ? 36.099 21.009 -1.773  1.00 68.75  ? 373 ARG   B CD  1 
ATOM   2722 N NE  . ARG   B 1 158 ? 36.494 20.034 -0.774  1.00 71.73  ? 373 ARG   B NE  1 
ATOM   2723 C CZ  . ARG   B 1 158 ? 36.938 20.398 0.418   1.00 73.44  ? 373 ARG   B CZ  1 
ATOM   2724 N NH1 . ARG   B 1 158 ? 37.061 21.680 0.739   1.00 73.43  ? 373 ARG   B NH1 1 
ATOM   2725 N NH2 . ARG   B 1 158 ? 37.269 19.463 1.310   1.00 74.78  ? 373 ARG   B NH2 1 
ATOM   2726 N N   . LEU   B 1 159 ? 37.818 24.136 -6.240  1.00 62.69  ? 374 LEU   B N   1 
ATOM   2727 C CA  . LEU   B 1 159 ? 37.287 24.962 -7.309  1.00 58.26  ? 374 LEU   B CA  1 
ATOM   2728 C C   . LEU   B 1 159 ? 36.334 24.063 -8.081  1.00 61.65  ? 374 LEU   B C   1 
ATOM   2729 O O   . LEU   B 1 159 ? 36.666 23.567 -9.149  1.00 58.56  ? 374 LEU   B O   1 
ATOM   2730 C CB  . LEU   B 1 159 ? 38.421 25.502 -8.204  1.00 59.02  ? 374 LEU   B CB  1 
ATOM   2731 C CG  . LEU   B 1 159 ? 39.616 26.285 -7.625  1.00 61.85  ? 374 LEU   B CG  1 
ATOM   2732 C CD1 . LEU   B 1 159 ? 40.711 25.340 -7.137  1.00 60.58  ? 374 LEU   B CD1 1 
ATOM   2733 C CD2 . LEU   B 1 159 ? 40.201 27.252 -8.687  1.00 62.83  ? 374 LEU   B CD2 1 
ATOM   2734 N N   . LEU   B 1 160 ? 35.174 23.791 -7.508  1.00 54.38  ? 375 LEU   B N   1 
ATOM   2735 C CA  . LEU   B 1 160 ? 34.309 22.747 -8.033  1.00 58.62  ? 375 LEU   B CA  1 
ATOM   2736 C C   . LEU   B 1 160 ? 33.229 23.365 -8.901  1.00 60.17  ? 375 LEU   B C   1 
ATOM   2737 O O   . LEU   B 1 160 ? 32.725 24.457 -8.612  1.00 56.67  ? 375 LEU   B O   1 
ATOM   2738 C CB  . LEU   B 1 160 ? 33.671 21.931 -6.899  1.00 60.23  ? 375 LEU   B CB  1 
ATOM   2739 C CG  . LEU   B 1 160 ? 34.675 21.327 -5.915  1.00 60.99  ? 375 LEU   B CG  1 
ATOM   2740 C CD1 . LEU   B 1 160 ? 33.983 20.644 -4.759  1.00 63.39  ? 375 LEU   B CD1 1 
ATOM   2741 C CD2 . LEU   B 1 160 ? 35.544 20.340 -6.633  1.00 61.38  ? 375 LEU   B CD2 1 
ATOM   2742 N N   . ARG   B 1 161 ? 32.865 22.655 -9.954  1.00 58.98  ? 376 ARG   B N   1 
ATOM   2743 C CA  . ARG   B 1 161 ? 31.747 23.042 -10.805 1.00 60.40  ? 376 ARG   B CA  1 
ATOM   2744 C C   . ARG   B 1 161 ? 31.906 24.445 -11.395 1.00 57.18  ? 376 ARG   B C   1 
ATOM   2745 O O   . ARG   B 1 161 ? 30.918 25.157 -11.582 1.00 55.31  ? 376 ARG   B O   1 
ATOM   2746 C CB  . ARG   B 1 161 ? 30.424 22.926 -10.049 1.00 60.59  ? 376 ARG   B CB  1 
ATOM   2747 C CG  . ARG   B 1 161 ? 30.252 21.590 -9.337  1.00 62.95  ? 376 ARG   B CG  1 
ATOM   2748 C CD  . ARG   B 1 161 ? 28.929 21.479 -8.589  1.00 64.02  ? 376 ARG   B CD  1 
ATOM   2749 N NE  . ARG   B 1 161 ? 27.786 21.733 -9.457  1.00 66.25  ? 376 ARG   B NE  1 
ATOM   2750 C CZ  . ARG   B 1 161 ? 27.310 20.853 -10.329 1.00 67.09  ? 376 ARG   B CZ  1 
ATOM   2751 N NH1 . ARG   B 1 161 ? 27.840 19.644 -10.453 1.00 65.41  ? 376 ARG   B NH1 1 
ATOM   2752 N NH2 . ARG   B 1 161 ? 26.276 21.191 -11.096 1.00 65.53  ? 376 ARG   B NH2 1 
ATOM   2753 N N   . SER   B 1 162 ? 33.136 24.846 -11.747 1.00 57.01  ? 377 SER   B N   1 
ATOM   2754 C CA  . SER   B 1 162 ? 33.274 26.085 -12.506 1.00 57.57  ? 377 SER   B CA  1 
ATOM   2755 C C   . SER   B 1 162 ? 32.592 25.879 -13.845 1.00 57.47  ? 377 SER   B C   1 
ATOM   2756 O O   . SER   B 1 162 ? 32.868 24.872 -14.522 1.00 58.00  ? 377 SER   B O   1 
ATOM   2757 C CB  . SER   B 1 162 ? 34.724 26.475 -12.814 1.00 58.05  ? 377 SER   B CB  1 
ATOM   2758 O OG  . SER   B 1 162 ? 35.619 26.136 -11.778 1.00 59.56  ? 377 SER   B OG  1 
ATOM   2759 N N   . PRO   B 1 163 ? 31.779 26.819 -14.309 1.00 56.11  ? 378 PRO   B N   1 
ATOM   2760 C CA  . PRO   B 1 163 ? 31.290 26.735 -15.697 1.00 59.47  ? 378 PRO   B CA  1 
ATOM   2761 C C   . PRO   B 1 163 ? 32.440 26.702 -16.710 1.00 59.44  ? 378 PRO   B C   1 
ATOM   2762 O O   . PRO   B 1 163 ? 33.351 27.532 -16.679 1.00 59.04  ? 378 PRO   B O   1 
ATOM   2763 C CB  . PRO   B 1 163 ? 30.430 27.990 -15.847 1.00 58.15  ? 378 PRO   B CB  1 
ATOM   2764 C CG  . PRO   B 1 163 ? 30.021 28.334 -14.405 1.00 56.15  ? 378 PRO   B CG  1 
ATOM   2765 C CD  . PRO   B 1 163 ? 31.199 27.948 -13.565 1.00 55.97  ? 378 PRO   B CD  1 
ATOM   2766 N N   . MET   B 1 164 ? 32.400 25.712 -17.594 1.00 55.98  ? 379 MET   B N   1 
ATOM   2767 C CA  . MET   B 1 164 ? 33.284 25.668 -18.756 1.00 63.36  ? 379 MET   B CA  1 
ATOM   2768 C C   . MET   B 1 164 ? 33.125 26.919 -19.603 1.00 58.91  ? 379 MET   B C   1 
ATOM   2769 O O   . MET   B 1 164 ? 32.003 27.362 -19.857 1.00 56.87  ? 379 MET   B O   1 
ATOM   2770 C CB  . MET   B 1 164 ? 32.963 24.402 -19.557 1.00 58.68  ? 379 MET   B CB  1 
ATOM   2771 C CG  . MET   B 1 164 ? 34.157 23.679 -20.137 1.00 62.11  ? 379 MET   B CG  1 
ATOM   2772 S SD  . MET   B 1 164 ? 33.641 22.399 -21.301 1.00 51.16  ? 379 MET   B SD  1 
ATOM   2773 C CE  . MET   B 1 164 ? 34.138 21.020 -20.335 1.00 60.25  ? 379 MET   B CE  1 
ATOM   2774 N N   . CYS   B 1 165 ? 34.241 27.528 -20.005 1.00 61.00  ? 380 CYS   B N   1 
ATOM   2775 C CA  . CYS   B 1 165 ? 34.097 28.763 -20.767 1.00 63.39  ? 380 CYS   B CA  1 
ATOM   2776 C C   . CYS   B 1 165 ? 33.453 28.414 -22.093 1.00 62.41  ? 380 CYS   B C   1 
ATOM   2777 O O   . CYS   B 1 165 ? 33.759 27.386 -22.694 1.00 62.40  ? 380 CYS   B O   1 
ATOM   2778 C CB  . CYS   B 1 165 ? 35.424 29.466 -21.026 1.00 65.05  ? 380 CYS   B CB  1 
ATOM   2779 S SG  . CYS   B 1 165 ? 36.746 28.370 -21.536 1.00 73.09  ? 380 CYS   B SG  1 
ATOM   2780 N N   . GLU   B 1 166 ? 32.546 29.265 -22.547 1.00 65.15  ? 381 GLU   B N   1 
ATOM   2781 C CA  . GLU   B 1 166 ? 31.713 28.940 -23.700 1.00 67.80  ? 381 GLU   B CA  1 
ATOM   2782 C C   . GLU   B 1 166 ? 32.522 28.607 -24.955 1.00 66.72  ? 381 GLU   B C   1 
ATOM   2783 O O   . GLU   B 1 166 ? 31.945 28.119 -25.934 1.00 67.15  ? 381 GLU   B O   1 
ATOM   2784 C CB  . GLU   B 1 166 ? 30.768 30.112 -23.928 1.00 70.48  ? 381 GLU   B CB  1 
ATOM   2785 C CG  . GLU   B 1 166 ? 29.595 29.878 -24.842 1.00 76.42  ? 381 GLU   B CG  1 
ATOM   2786 C CD  . GLU   B 1 166 ? 28.989 31.212 -25.281 1.00 84.71  ? 381 GLU   B CD  1 
ATOM   2787 O OE1 . GLU   B 1 166 ? 29.709 32.227 -25.177 1.00 90.39  ? 381 GLU   B OE1 1 
ATOM   2788 O OE2 . GLU   B 1 166 ? 27.807 31.263 -25.707 1.00 90.18  ? 381 GLU   B OE2 1 
ATOM   2789 N N   . TYR   B 1 167 ? 33.839 28.837 -24.955 1.00 64.68  ? 382 TYR   B N   1 
ATOM   2790 C CA  . TYR   B 1 167 ? 34.657 28.477 -26.105 1.00 64.54  ? 382 TYR   B CA  1 
ATOM   2791 C C   . TYR   B 1 167 ? 34.936 26.991 -26.112 1.00 67.85  ? 382 TYR   B C   1 
ATOM   2792 O O   . TYR   B 1 167 ? 34.877 26.352 -27.168 1.00 65.13  ? 382 TYR   B O   1 
ATOM   2793 C CB  . TYR   B 1 167 ? 35.979 29.248 -26.087 1.00 64.86  ? 382 TYR   B CB  1 
ATOM   2794 C CG  . TYR   B 1 167 ? 36.956 28.811 -27.149 1.00 65.36  ? 382 TYR   B CG  1 
ATOM   2795 C CD1 . TYR   B 1 167 ? 37.763 27.704 -26.973 1.00 64.58  ? 382 TYR   B CD1 1 
ATOM   2796 C CD2 . TYR   B 1 167 ? 37.068 29.515 -28.334 1.00 67.15  ? 382 TYR   B CD2 1 
ATOM   2797 C CE1 . TYR   B 1 167 ? 38.644 27.286 -27.969 1.00 65.77  ? 382 TYR   B CE1 1 
ATOM   2798 C CE2 . TYR   B 1 167 ? 37.947 29.109 -29.334 1.00 67.57  ? 382 TYR   B CE2 1 
ATOM   2799 C CZ  . TYR   B 1 167 ? 38.730 27.996 -29.138 1.00 67.38  ? 382 TYR   B CZ  1 
ATOM   2800 O OH  . TYR   B 1 167 ? 39.608 27.613 -30.127 1.00 69.77  ? 382 TYR   B OH  1 
ATOM   2801 N N   . LEU   B 1 168 ? 35.292 26.431 -24.953 1.00 63.58  ? 383 LEU   B N   1 
ATOM   2802 C CA  . LEU   B 1 168 ? 35.454 24.992 -24.873 1.00 66.26  ? 383 LEU   B CA  1 
ATOM   2803 C C   . LEU   B 1 168 ? 34.155 24.285 -25.217 1.00 67.13  ? 383 LEU   B C   1 
ATOM   2804 O O   . LEU   B 1 168 ? 34.163 23.276 -25.931 1.00 64.93  ? 383 LEU   B O   1 
ATOM   2805 C CB  . LEU   B 1 168 ? 35.948 24.584 -23.492 1.00 65.07  ? 383 LEU   B CB  1 
ATOM   2806 C CG  . LEU   B 1 168 ? 37.451 24.754 -23.275 1.00 65.38  ? 383 LEU   B CG  1 
ATOM   2807 C CD1 . LEU   B 1 168 ? 37.894 24.128 -21.983 1.00 65.91  ? 383 LEU   B CD1 1 
ATOM   2808 C CD2 . LEU   B 1 168 ? 38.272 24.178 -24.437 1.00 67.09  ? 383 LEU   B CD2 1 
ATOM   2809 N N   . VAL   B 1 169 ? 33.023 24.808 -24.747 1.00 64.44  ? 384 VAL   B N   1 
ATOM   2810 C CA  . VAL   B 1 169 ? 31.776 24.091 -24.972 1.00 69.08  ? 384 VAL   B CA  1 
ATOM   2811 C C   . VAL   B 1 169 ? 31.469 24.041 -26.449 1.00 64.75  ? 384 VAL   B C   1 
ATOM   2812 O O   . VAL   B 1 169 ? 31.058 23.003 -26.972 1.00 63.89  ? 384 VAL   B O   1 
ATOM   2813 C CB  . VAL   B 1 169 ? 30.624 24.711 -24.165 1.00 67.88  ? 384 VAL   B CB  1 
ATOM   2814 C CG1 . VAL   B 1 169 ? 29.349 23.931 -24.393 1.00 65.78  ? 384 VAL   B CG1 1 
ATOM   2815 C CG2 . VAL   B 1 169 ? 30.986 24.710 -22.690 1.00 65.46  ? 384 VAL   B CG2 1 
ATOM   2816 N N   . ASN   B 1 170 ? 31.676 25.157 -27.153 1.00 66.67  ? 385 ASN   B N   1 
ATOM   2817 C CA  . ASN   B 1 170 ? 31.438 25.147 -28.582 1.00 63.11  ? 385 ASN   B CA  1 
ATOM   2818 C C   . ASN   B 1 170 ? 32.496 24.305 -29.284 1.00 65.46  ? 385 ASN   B C   1 
ATOM   2819 O O   . ASN   B 1 170 ? 32.187 23.541 -30.212 1.00 65.07  ? 385 ASN   B O   1 
ATOM   2820 C CB  . ASN   B 1 170 ? 31.446 26.580 -29.097 1.00 64.93  ? 385 ASN   B CB  1 
ATOM   2821 C CG  . ASN   B 1 170 ? 30.300 27.409 -28.525 1.00 72.55  ? 385 ASN   B CG  1 
ATOM   2822 O OD1 . ASN   B 1 170 ? 30.442 28.615 -28.325 1.00 75.12  ? 385 ASN   B OD1 1 
ATOM   2823 N ND2 . ASN   B 1 170 ? 29.165 26.758 -28.221 1.00 75.37  ? 385 ASN   B ND2 1 
ATOM   2824 N N   . PHE   B 1 171 ? 33.759 24.423 -28.867 1.00 61.96  ? 386 PHE   B N   1 
ATOM   2825 C CA  . PHE   B 1 171 ? 34.783 23.624 -29.522 1.00 65.52  ? 386 PHE   B CA  1 
ATOM   2826 C C   . PHE   B 1 171 ? 34.442 22.142 -29.441 1.00 69.16  ? 386 PHE   B C   1 
ATOM   2827 O O   . PHE   B 1 171 ? 34.645 21.395 -30.406 1.00 65.00  ? 386 PHE   B O   1 
ATOM   2828 C CB  . PHE   B 1 171 ? 36.146 23.908 -28.906 1.00 64.15  ? 386 PHE   B CB  1 
ATOM   2829 C CG  . PHE   B 1 171 ? 37.232 23.014 -29.424 1.00 64.50  ? 386 PHE   B CG  1 
ATOM   2830 C CD1 . PHE   B 1 171 ? 37.715 23.171 -30.730 1.00 63.00  ? 386 PHE   B CD1 1 
ATOM   2831 C CD2 . PHE   B 1 171 ? 37.788 22.049 -28.622 1.00 60.71  ? 386 PHE   B CD2 1 
ATOM   2832 C CE1 . PHE   B 1 171 ? 38.724 22.351 -31.217 1.00 60.26  ? 386 PHE   B CE1 1 
ATOM   2833 C CE2 . PHE   B 1 171 ? 38.792 21.234 -29.085 1.00 62.31  ? 386 PHE   B CE2 1 
ATOM   2834 C CZ  . PHE   B 1 171 ? 39.268 21.375 -30.397 1.00 63.17  ? 386 PHE   B CZ  1 
ATOM   2835 N N   . LEU   B 1 172 ? 33.902 21.709 -28.300 1.00 63.25  ? 387 LEU   B N   1 
ATOM   2836 C CA  . LEU   B 1 172 ? 33.526 20.316 -28.117 1.00 67.15  ? 387 LEU   B CA  1 
ATOM   2837 C C   . LEU   B 1 172 ? 32.329 19.947 -28.968 1.00 63.70  ? 387 LEU   B C   1 
ATOM   2838 O O   . LEU   B 1 172 ? 32.278 18.855 -29.527 1.00 63.08  ? 387 LEU   B O   1 
ATOM   2839 C CB  . LEU   B 1 172 ? 33.205 20.045 -26.646 1.00 68.28  ? 387 LEU   B CB  1 
ATOM   2840 C CG  . LEU   B 1 172 ? 34.357 19.891 -25.672 1.00 63.61  ? 387 LEU   B CG  1 
ATOM   2841 C CD1 . LEU   B 1 172 ? 33.794 19.994 -24.253 1.00 64.57  ? 387 LEU   B CD1 1 
ATOM   2842 C CD2 . LEU   B 1 172 ? 35.067 18.561 -25.891 1.00 63.32  ? 387 LEU   B CD2 1 
ATOM   2843 N N   . HIS   B 1 173 ? 31.323 20.805 -29.035 1.00 67.05  ? 388 HIS   B N   1 
ATOM   2844 C CA  . HIS   B 1 173 ? 30.202 20.477 -29.899 1.00 68.35  ? 388 HIS   B CA  1 
ATOM   2845 C C   . HIS   B 1 173 ? 30.669 20.312 -31.333 1.00 70.12  ? 388 HIS   B C   1 
ATOM   2846 O O   . HIS   B 1 173 ? 30.273 19.366 -32.022 1.00 68.40  ? 388 HIS   B O   1 
ATOM   2847 C CB  . HIS   B 1 173 ? 29.129 21.551 -29.801 1.00 67.42  ? 388 HIS   B CB  1 
ATOM   2848 C CG  . HIS   B 1 173 ? 27.987 21.167 -28.916 1.00 71.73  ? 388 HIS   B CG  1 
ATOM   2849 N ND1 . HIS   B 1 173 ? 27.986 21.422 -27.561 1.00 70.75  ? 388 HIS   B ND1 1 
ATOM   2850 C CD2 . HIS   B 1 173 ? 26.801 20.567 -29.187 1.00 74.31  ? 388 HIS   B CD2 1 
ATOM   2851 C CE1 . HIS   B 1 173 ? 26.857 20.983 -27.031 1.00 73.94  ? 388 HIS   B CE1 1 
ATOM   2852 N NE2 . HIS   B 1 173 ? 26.116 20.465 -27.997 1.00 78.16  ? 388 HIS   B NE2 1 
ATOM   2853 N N   . LYS   B 1 174 ? 31.511 21.231 -31.805 1.00 65.99  ? 389 LYS   B N   1 
ATOM   2854 C CA  . LYS   B 1 174 ? 32.044 21.087 -33.152 1.00 70.64  ? 389 LYS   B CA  1 
ATOM   2855 C C   . LYS   B 1 174 ? 32.854 19.812 -33.269 1.00 68.94  ? 389 LYS   B C   1 
ATOM   2856 O O   . LYS   B 1 174 ? 32.622 18.993 -34.166 1.00 69.99  ? 389 LYS   B O   1 
ATOM   2857 C CB  . LYS   B 1 174 ? 32.898 22.296 -33.530 1.00 64.90  ? 389 LYS   B CB  1 
ATOM   2858 C CG  . LYS   B 1 174 ? 32.089 23.520 -33.808 1.00 63.78  ? 389 LYS   B CG  1 
ATOM   2859 C CD  . LYS   B 1 174 ? 32.919 24.727 -33.570 1.00 64.16  ? 389 LYS   B CD  1 
ATOM   2860 C CE  . LYS   B 1 174 ? 32.111 25.951 -33.809 1.00 64.25  ? 389 LYS   B CE  1 
ATOM   2861 N NZ  . LYS   B 1 174 ? 33.041 27.091 -33.789 1.00 66.95  ? 389 LYS   B NZ  1 
ATOM   2862 N N   . LEU   B 1 175 ? 33.808 19.619 -32.363 1.00 68.00  ? 390 LEU   B N   1 
ATOM   2863 C CA  . LEU   B 1 175 ? 34.662 18.448 -32.465 1.00 67.88  ? 390 LEU   B CA  1 
ATOM   2864 C C   . LEU   B 1 175 ? 33.833 17.171 -32.541 1.00 68.33  ? 390 LEU   B C   1 
ATOM   2865 O O   . LEU   B 1 175 ? 34.173 16.243 -33.282 1.00 68.43  ? 390 LEU   B O   1 
ATOM   2866 C CB  . LEU   B 1 175 ? 35.627 18.436 -31.292 1.00 65.32  ? 390 LEU   B CB  1 
ATOM   2867 C CG  . LEU   B 1 175 ? 36.886 17.594 -31.429 1.00 65.28  ? 390 LEU   B CG  1 
ATOM   2868 C CD1 . LEU   B 1 175 ? 37.697 17.973 -32.691 1.00 64.30  ? 390 LEU   B CD1 1 
ATOM   2869 C CD2 . LEU   B 1 175 ? 37.746 17.684 -30.158 1.00 62.83  ? 390 LEU   B CD2 1 
ATOM   2870 N N   . ARG   B 1 176 ? 32.694 17.165 -31.891 1.00 67.59  ? 391 ARG   B N   1 
ATOM   2871 C CA  . ARG   B 1 176 ? 31.870 15.982 -31.789 1.00 67.58  ? 391 ARG   B CA  1 
ATOM   2872 C C   . ARG   B 1 176 ? 31.249 15.584 -33.093 1.00 67.91  ? 391 ARG   B C   1 
ATOM   2873 O O   . ARG   B 1 176 ? 30.842 14.463 -33.254 1.00 66.58  ? 391 ARG   B O   1 
ATOM   2874 C CB  . ARG   B 1 176 ? 30.774 16.232 -30.757 1.00 68.46  ? 391 ARG   B CB  1 
ATOM   2875 C CG  . ARG   B 1 176 ? 29.562 15.326 -30.804 1.00 70.13  ? 391 ARG   B CG  1 
ATOM   2876 C CD  . ARG   B 1 176 ? 29.774 14.100 -29.930 1.00 73.73  ? 391 ARG   B CD  1 
ATOM   2877 N NE  . ARG   B 1 176 ? 28.636 13.673 -29.114 1.00 76.75  ? 391 ARG   B NE  1 
ATOM   2878 C CZ  . ARG   B 1 176 ? 27.718 14.473 -28.591 1.00 79.00  ? 391 ARG   B CZ  1 
ATOM   2879 N NH1 . ARG   B 1 176 ? 26.753 13.960 -27.850 1.00 79.13  ? 391 ARG   B NH1 1 
ATOM   2880 N NH2 . ARG   B 1 176 ? 27.756 15.771 -28.807 1.00 78.64  ? 391 ARG   B NH2 1 
ATOM   2881 N N   . GLN   B 1 177 ? 31.160 16.508 -34.024 1.00 69.12  ? 392 GLN   B N   1 
ATOM   2882 C CA  . GLN   B 1 177 ? 30.435 16.251 -35.252 1.00 72.71  ? 392 GLN   B CA  1 
ATOM   2883 C C   . GLN   B 1 177 ? 31.330 15.813 -36.400 1.00 73.23  ? 392 GLN   B C   1 
ATOM   2884 O O   . GLN   B 1 177 ? 30.821 15.229 -37.359 1.00 73.32  ? 392 GLN   B O   1 
ATOM   2885 C CB  . GLN   B 1 177 ? 29.652 17.496 -35.663 1.00 76.39  ? 392 GLN   B CB  1 
ATOM   2886 C CG  . GLN   B 1 177 ? 28.456 17.732 -34.757 1.00 79.07  ? 392 GLN   B CG  1 
ATOM   2887 C CD  . GLN   B 1 177 ? 28.247 19.195 -34.467 1.00 83.69  ? 392 GLN   B CD  1 
ATOM   2888 O OE1 . GLN   B 1 177 ? 28.428 20.043 -35.351 1.00 86.88  ? 392 GLN   B OE1 1 
ATOM   2889 N NE2 . GLN   B 1 177 ? 27.905 19.514 -33.211 1.00 80.39  ? 392 GLN   B NE2 1 
ATOM   2890 N N   . LEU   B 1 178 ? 32.644 16.082 -36.321 1.00 70.15  ? 393 LEU   B N   1 
ATOM   2891 C CA  . LEU   B 1 178 ? 33.645 15.592 -37.256 1.00 70.19  ? 393 LEU   B CA  1 
ATOM   2892 C C   . LEU   B 1 178 ? 33.318 14.154 -37.630 1.00 71.27  ? 393 LEU   B C   1 
ATOM   2893 O O   . LEU   B 1 178 ? 32.982 13.343 -36.752 1.00 70.25  ? 393 LEU   B O   1 
ATOM   2894 C CB  . LEU   B 1 178 ? 35.048 15.682 -36.653 1.00 67.81  ? 393 LEU   B CB  1 
ATOM   2895 C CG  . LEU   B 1 178 ? 35.813 16.961 -36.960 1.00 67.68  ? 393 LEU   B CG  1 
ATOM   2896 C CD1 . LEU   B 1 178 ? 34.869 18.121 -36.836 1.00 68.37  ? 393 LEU   B CD1 1 
ATOM   2897 C CD2 . LEU   B 1 178 ? 37.017 17.121 -36.067 1.00 64.84  ? 393 LEU   B CD2 1 
ATOM   2898 N N   . PRO   B 1 179 ? 33.409 13.810 -38.917 1.00 70.38  ? 394 PRO   B N   1 
ATOM   2899 C CA  . PRO   B 1 179 ? 32.975 12.477 -39.366 1.00 70.85  ? 394 PRO   B CA  1 
ATOM   2900 C C   . PRO   B 1 179 ? 33.906 11.348 -38.960 1.00 69.45  ? 394 PRO   B C   1 
ATOM   2901 O O   . PRO   B 1 179 ? 33.462 10.199 -38.920 1.00 71.57  ? 394 PRO   B O   1 
ATOM   2902 C CB  . PRO   B 1 179 ? 32.942 12.611 -40.898 1.00 70.12  ? 394 PRO   B CB  1 
ATOM   2903 C CG  . PRO   B 1 179 ? 33.144 14.070 -41.200 1.00 70.27  ? 394 PRO   B CG  1 
ATOM   2904 C CD  . PRO   B 1 179 ? 33.898 14.628 -40.037 1.00 70.94  ? 394 PRO   B CD  1 
ATOM   2905 N N   . GLU   B 1 180 ? 35.177 11.627 -38.672 1.00 68.31  ? 395 GLU   B N   1 
ATOM   2906 C CA  . GLU   B 1 180 ? 36.188 10.594 -38.500 1.00 65.55  ? 395 GLU   B CA  1 
ATOM   2907 C C   . GLU   B 1 180 ? 37.014 10.898 -37.267 1.00 62.54  ? 395 GLU   B C   1 
ATOM   2908 O O   . GLU   B 1 180 ? 37.343 12.062 -37.011 1.00 64.52  ? 395 GLU   B O   1 
ATOM   2909 C CB  . GLU   B 1 180 ? 37.111 10.523 -39.713 1.00 63.78  ? 395 GLU   B CB  1 
ATOM   2910 C CG  . GLU   B 1 180 ? 36.425 10.179 -40.997 1.00 65.78  ? 395 GLU   B CG  1 
ATOM   2911 C CD  . GLU   B 1 180 ? 36.099 8.730  -41.045 1.00 68.75  ? 395 GLU   B CD  1 
ATOM   2912 O OE1 . GLU   B 1 180 ? 36.225 8.107  -39.962 1.00 68.36  ? 395 GLU   B OE1 1 
ATOM   2913 O OE2 . GLU   B 1 180 ? 35.734 8.218  -42.133 1.00 70.02  ? 395 GLU   B OE2 1 
ATOM   2914 N N   . ARG   B 1 181 ? 37.386 9.845  -36.537 1.00 61.27  ? 396 ARG   B N   1 
ATOM   2915 C CA  . ARG   B 1 181 ? 38.154 10.026 -35.305 1.00 63.38  ? 396 ARG   B CA  1 
ATOM   2916 C C   . ARG   B 1 181 ? 39.553 10.549 -35.600 1.00 63.32  ? 396 ARG   B C   1 
ATOM   2917 O O   . ARG   B 1 181 ? 40.082 11.385 -34.857 1.00 61.64  ? 396 ARG   B O   1 
ATOM   2918 C CB  . ARG   B 1 181 ? 38.220 8.706  -34.519 1.00 65.41  ? 396 ARG   B CB  1 
ATOM   2919 C CG  . ARG   B 1 181 ? 38.072 8.854  -32.988 1.00 67.81  ? 396 ARG   B CG  1 
ATOM   2920 C CD  . ARG   B 1 181 ? 38.649 7.613  -32.252 1.00 71.42  ? 396 ARG   B CD  1 
ATOM   2921 N NE  . ARG   B 1 181 ? 39.993 7.318  -32.748 1.00 72.45  ? 396 ARG   B NE  1 
ATOM   2922 C CZ  . ARG   B 1 181 ? 40.773 6.349  -32.290 1.00 75.29  ? 396 ARG   B CZ  1 
ATOM   2923 N NH1 . ARG   B 1 181 ? 40.397 5.585  -31.281 1.00 78.89  ? 396 ARG   B NH1 1 
ATOM   2924 N NH2 . ARG   B 1 181 ? 41.954 6.129  -32.873 1.00 78.16  ? 396 ARG   B NH2 1 
ATOM   2925 N N   . TYR   B 1 182 ? 40.164 10.093 -36.688 1.00 59.77  ? 397 TYR   B N   1 
ATOM   2926 C CA  . TYR   B 1 182 ? 41.467 10.632 -37.044 1.00 61.77  ? 397 TYR   B CA  1 
ATOM   2927 C C   . TYR   B 1 182 ? 41.389 12.119 -37.332 1.00 59.11  ? 397 TYR   B C   1 
ATOM   2928 O O   . TYR   B 1 182 ? 42.399 12.823 -37.179 1.00 57.62  ? 397 TYR   B O   1 
ATOM   2929 C CB  . TYR   B 1 182 ? 42.056 9.893  -38.245 1.00 63.56  ? 397 TYR   B CB  1 
ATOM   2930 C CG  . TYR   B 1 182 ? 41.490 10.271 -39.601 1.00 63.29  ? 397 TYR   B CG  1 
ATOM   2931 C CD1 . TYR   B 1 182 ? 41.764 11.521 -40.173 1.00 62.67  ? 397 TYR   B CD1 1 
ATOM   2932 C CD2 . TYR   B 1 182 ? 40.759 9.359  -40.343 1.00 64.25  ? 397 TYR   B CD2 1 
ATOM   2933 C CE1 . TYR   B 1 182 ? 41.274 11.868 -41.424 1.00 67.94  ? 397 TYR   B CE1 1 
ATOM   2934 C CE2 . TYR   B 1 182 ? 40.271 9.693  -41.604 1.00 66.66  ? 397 TYR   B CE2 1 
ATOM   2935 C CZ  . TYR   B 1 182 ? 40.538 10.944 -42.136 1.00 65.62  ? 397 TYR   B CZ  1 
ATOM   2936 O OH  . TYR   B 1 182 ? 40.039 11.293 -43.356 1.00 64.62  ? 397 TYR   B OH  1 
ATOM   2937 N N   . MET   B 1 183 ? 40.216 12.617 -37.745 1.00 57.55  ? 398 MET   B N   1 
ATOM   2938 C CA  . MET   B 1 183 ? 40.073 14.051 -37.981 1.00 63.01  ? 398 MET   B CA  1 
ATOM   2939 C C   . MET   B 1 183 ? 40.026 14.817 -36.648 1.00 60.48  ? 398 MET   B C   1 
ATOM   2940 O O   . MET   B 1 183 ? 40.717 15.829 -36.476 1.00 59.27  ? 398 MET   B O   1 
ATOM   2941 C CB  . MET   B 1 183 ? 38.830 14.325 -38.850 1.00 60.99  ? 398 MET   B CB  1 
ATOM   2942 C CG  . MET   B 1 183 ? 39.066 14.358 -40.315 1.00 63.97  ? 398 MET   B CG  1 
ATOM   2943 S SD  . MET   B 1 183 ? 37.578 14.375 -41.388 1.00 59.10  ? 398 MET   B SD  1 
ATOM   2944 C CE  . MET   B 1 183 ? 38.132 13.444 -42.806 1.00 67.12  ? 398 MET   B CE  1 
ATOM   2945 N N   . MET   B 1 184 ? 39.209 14.360 -35.705 1.00 60.12  ? 399 MET   B N   1 
ATOM   2946 C CA  . MET   B 1 184 ? 39.247 14.924 -34.353 1.00 62.01  ? 399 MET   B CA  1 
ATOM   2947 C C   . MET   B 1 184 ? 40.665 14.914 -33.807 1.00 61.31  ? 399 MET   B C   1 
ATOM   2948 O O   . MET   B 1 184 ? 41.112 15.878 -33.173 1.00 60.29  ? 399 MET   B O   1 
ATOM   2949 C CB  . MET   B 1 184 ? 38.311 14.137 -33.430 1.00 59.93  ? 399 MET   B CB  1 
ATOM   2950 C CG  . MET   B 1 184 ? 36.928 13.853 -33.989 1.00 63.00  ? 399 MET   B CG  1 
ATOM   2951 S SD  . MET   B 1 184 ? 35.899 12.812 -32.930 1.00 57.24  ? 399 MET   B SD  1 
ATOM   2952 C CE  . MET   B 1 184 ? 34.255 13.377 -33.448 1.00 65.62  ? 399 MET   B CE  1 
ATOM   2953 N N   . ASN   B 1 185 ? 41.402 13.843 -34.079 1.00 59.48  ? 400 ASN   B N   1 
ATOM   2954 C CA  . ASN   B 1 185 ? 42.783 13.756 -33.616 1.00 61.84  ? 400 ASN   B CA  1 
ATOM   2955 C C   . ASN   B 1 185 ? 43.697 14.721 -34.366 1.00 61.36  ? 400 ASN   B C   1 
ATOM   2956 O O   . ASN   B 1 185 ? 44.603 15.313 -33.765 1.00 58.00  ? 400 ASN   B O   1 
ATOM   2957 C CB  . ASN   B 1 185 ? 43.286 12.313 -33.741 1.00 61.43  ? 400 ASN   B CB  1 
ATOM   2958 C CG  . ASN   B 1 185 ? 42.864 11.466 -32.566 1.00 63.30  ? 400 ASN   B CG  1 
ATOM   2959 O OD1 . ASN   B 1 185 ? 42.535 12.006 -31.524 1.00 61.46  ? 400 ASN   B OD1 1 
ATOM   2960 N ND2 . ASN   B 1 185 ? 42.878 10.144 -32.720 1.00 63.41  ? 400 ASN   B ND2 1 
ATOM   2961 N N   . SER   B 1 186 ? 43.490 14.907 -35.675 1.00 59.81  ? 401 SER   B N   1 
ATOM   2962 C CA  . SER   B 1 186 ? 44.257 15.942 -36.370 1.00 63.06  ? 401 SER   B CA  1 
ATOM   2963 C C   . SER   B 1 186 ? 44.036 17.294 -35.715 1.00 60.40  ? 401 SER   B C   1 
ATOM   2964 O O   . SER   B 1 186 ? 44.984 18.064 -35.504 1.00 54.91  ? 401 SER   B O   1 
ATOM   2965 C CB  . SER   B 1 186 ? 43.868 16.033 -37.844 1.00 62.36  ? 401 SER   B CB  1 
ATOM   2966 O OG  . SER   B 1 186 ? 44.005 14.775 -38.498 1.00 62.28  ? 401 SER   B OG  1 
ATOM   2967 N N   . VAL   B 1 187 ? 42.770 17.632 -35.462 1.00 56.57  ? 402 VAL   B N   1 
ATOM   2968 C CA  . VAL   B 1 187 ? 42.444 18.909 -34.840 1.00 66.21  ? 402 VAL   B CA  1 
ATOM   2969 C C   . VAL   B 1 187 ? 43.112 19.015 -33.473 1.00 60.06  ? 402 VAL   B C   1 
ATOM   2970 O O   . VAL   B 1 187 ? 43.720 20.036 -33.138 1.00 54.09  ? 402 VAL   B O   1 
ATOM   2971 C CB  . VAL   B 1 187 ? 40.919 19.075 -34.736 1.00 62.96  ? 402 VAL   B CB  1 
ATOM   2972 C CG1 . VAL   B 1 187 ? 40.571 20.376 -34.011 1.00 61.65  ? 402 VAL   B CG1 1 
ATOM   2973 C CG2 . VAL   B 1 187 ? 40.293 19.004 -36.093 1.00 60.09  ? 402 VAL   B CG2 1 
ATOM   2974 N N   . LEU   B 1 188 ? 43.064 17.940 -32.689 1.00 61.18  ? 403 LEU   B N   1 
ATOM   2975 C CA  . LEU   B 1 188 ? 43.601 18.037 -31.334 1.00 62.31  ? 403 LEU   B CA  1 
ATOM   2976 C C   . LEU   B 1 188 ? 45.124 18.148 -31.321 1.00 58.72  ? 403 LEU   B C   1 
ATOM   2977 O O   . LEU   B 1 188 ? 45.685 18.659 -30.344 1.00 54.08  ? 403 LEU   B O   1 
ATOM   2978 C CB  . LEU   B 1 188 ? 43.127 16.846 -30.494 1.00 62.28  ? 403 LEU   B CB  1 
ATOM   2979 C CG  . LEU   B 1 188 ? 41.605 16.796 -30.301 1.00 59.50  ? 403 LEU   B CG  1 
ATOM   2980 C CD1 . LEU   B 1 188 ? 41.175 15.435 -29.779 1.00 61.59  ? 403 LEU   B CD1 1 
ATOM   2981 C CD2 . LEU   B 1 188 ? 41.138 17.857 -29.350 1.00 59.62  ? 403 LEU   B CD2 1 
ATOM   2982 N N   . GLU   B 1 189 ? 45.810 17.729 -32.393 1.00 62.76  ? 404 GLU   B N   1 
ATOM   2983 C CA  . GLU   B 1 189 ? 47.260 17.929 -32.460 1.00 61.45  ? 404 GLU   B CA  1 
ATOM   2984 C C   . GLU   B 1 189 ? 47.613 19.364 -32.106 1.00 63.53  ? 404 GLU   B C   1 
ATOM   2985 O O   . GLU   B 1 189 ? 48.606 19.626 -31.410 1.00 62.75  ? 404 GLU   B O   1 
ATOM   2986 C CB  . GLU   B 1 189 ? 47.780 17.602 -33.850 1.00 61.65  ? 404 GLU   B CB  1 
ATOM   2987 C CG  . GLU   B 1 189 ? 48.411 16.236 -33.988 1.00 65.26  ? 404 GLU   B CG  1 
ATOM   2988 C CD  . GLU   B 1 189 ? 48.572 15.840 -35.456 1.00 73.75  ? 404 GLU   B CD  1 
ATOM   2989 O OE1 . GLU   B 1 189 ? 49.253 16.589 -36.195 1.00 76.48  ? 404 GLU   B OE1 1 
ATOM   2990 O OE2 . GLU   B 1 189 ? 48.013 14.783 -35.870 1.00 70.87  ? 404 GLU   B OE2 1 
ATOM   2991 N N   . ASN   B 1 190 ? 46.771 20.303 -32.536 1.00 58.30  ? 405 ASN   B N   1 
ATOM   2992 C CA  . ASN   B 1 190 ? 47.025 21.729 -32.433 1.00 64.95  ? 405 ASN   B CA  1 
ATOM   2993 C C   . ASN   B 1 190 ? 46.243 22.382 -31.312 1.00 65.52  ? 405 ASN   B C   1 
ATOM   2994 O O   . ASN   B 1 190 ? 46.001 23.588 -31.359 1.00 66.80  ? 405 ASN   B O   1 
ATOM   2995 C CB  . ASN   B 1 190 ? 46.697 22.381 -33.770 1.00 67.42  ? 405 ASN   B CB  1 
ATOM   2996 C CG  . ASN   B 1 190 ? 47.464 21.740 -34.921 1.00 68.27  ? 405 ASN   B CG  1 
ATOM   2997 O OD1 . ASN   B 1 190 ? 48.688 21.523 -34.831 1.00 65.95  ? 405 ASN   B OD1 1 
ATOM   2998 N ND2 . ASN   B 1 190 ? 46.754 21.421 -36.009 1.00 68.92  ? 405 ASN   B ND2 1 
ATOM   2999 N N   . PHE   B 1 191 ? 45.854 21.620 -30.295 1.00 63.23  ? 406 PHE   B N   1 
ATOM   3000 C CA  . PHE   B 1 191 ? 44.994 22.128 -29.232 1.00 63.44  ? 406 PHE   B CA  1 
ATOM   3001 C C   . PHE   B 1 191 ? 45.611 21.733 -27.899 1.00 65.94  ? 406 PHE   B C   1 
ATOM   3002 O O   . PHE   B 1 191 ? 45.739 20.544 -27.598 1.00 63.54  ? 406 PHE   B O   1 
ATOM   3003 C CB  . PHE   B 1 191 ? 43.571 21.587 -29.376 1.00 61.67  ? 406 PHE   B CB  1 
ATOM   3004 C CG  . PHE   B 1 191 ? 42.678 21.945 -28.231 1.00 60.23  ? 406 PHE   B CG  1 
ATOM   3005 C CD1 . PHE   B 1 191 ? 41.947 23.122 -28.240 1.00 60.29  ? 406 PHE   B CD1 1 
ATOM   3006 C CD2 . PHE   B 1 191 ? 42.576 21.107 -27.132 1.00 61.17  ? 406 PHE   B CD2 1 
ATOM   3007 C CE1 . PHE   B 1 191 ? 41.120 23.463 -27.154 1.00 61.62  ? 406 PHE   B CE1 1 
ATOM   3008 C CE2 . PHE   B 1 191 ? 41.747 21.443 -26.041 1.00 61.30  ? 406 PHE   B CE2 1 
ATOM   3009 C CZ  . PHE   B 1 191 ? 41.027 22.622 -26.064 1.00 60.11  ? 406 PHE   B CZ  1 
ATOM   3010 N N   . THR   B 1 192 ? 46.022 22.714 -27.106 1.00 60.08  ? 407 THR   B N   1 
ATOM   3011 C CA  . THR   B 1 192 ? 46.623 22.402 -25.824 1.00 66.49  ? 407 THR   B CA  1 
ATOM   3012 C C   . THR   B 1 192 ? 46.120 23.379 -24.766 1.00 67.73  ? 407 THR   B C   1 
ATOM   3013 O O   . THR   B 1 192 ? 45.605 24.459 -25.061 1.00 64.45  ? 407 THR   B O   1 
ATOM   3014 C CB  . THR   B 1 192 ? 48.154 22.431 -25.894 1.00 69.61  ? 407 THR   B CB  1 
ATOM   3015 O OG1 . THR   B 1 192 ? 48.573 23.774 -26.121 1.00 73.61  ? 407 THR   B OG1 1 
ATOM   3016 C CG2 . THR   B 1 192 ? 48.663 21.562 -27.030 1.00 71.07  ? 407 THR   B CG2 1 
ATOM   3017 N N   . ILE   B 1 193 ? 46.270 22.972 -23.520 1.00 65.14  ? 408 ILE   B N   1 
ATOM   3018 C CA  . ILE   B 1 193 ? 45.887 23.779 -22.378 1.00 66.30  ? 408 ILE   B CA  1 
ATOM   3019 C C   . ILE   B 1 193 ? 47.080 23.824 -21.445 1.00 63.83  ? 408 ILE   B C   1 
ATOM   3020 O O   . ILE   B 1 193 ? 47.780 22.823 -21.268 1.00 61.83  ? 408 ILE   B O   1 
ATOM   3021 C CB  . ILE   B 1 193 ? 44.638 23.212 -21.684 1.00 62.55  ? 408 ILE   B CB  1 
ATOM   3022 C CG1 . ILE   B 1 193 ? 43.450 23.322 -22.624 1.00 62.61  ? 408 ILE   B CG1 1 
ATOM   3023 C CG2 . ILE   B 1 193 ? 44.328 23.973 -20.387 1.00 64.50  ? 408 ILE   B CG2 1 
ATOM   3024 C CD1 . ILE   B 1 193 ? 42.224 22.706 -22.049 1.00 62.19  ? 408 ILE   B CD1 1 
ATOM   3025 N N   . LEU   B 1 194 ? 47.349 24.994 -20.892 1.00 65.06  ? 409 LEU   B N   1 
ATOM   3026 C CA  . LEU   B 1 194 ? 48.443 25.149 -19.952 1.00 66.12  ? 409 LEU   B CA  1 
ATOM   3027 C C   . LEU   B 1 194 ? 47.878 25.716 -18.656 1.00 65.76  ? 409 LEU   B C   1 
ATOM   3028 O O   . LEU   B 1 194 ? 47.292 26.802 -18.652 1.00 62.79  ? 409 LEU   B O   1 
ATOM   3029 C CB  . LEU   B 1 194 ? 49.528 26.043 -20.529 1.00 65.27  ? 409 LEU   B CB  1 
ATOM   3030 C CG  . LEU   B 1 194 ? 50.719 26.213 -19.601 1.00 66.51  ? 409 LEU   B CG  1 
ATOM   3031 C CD1 . LEU   B 1 194 ? 51.453 24.907 -19.476 1.00 66.07  ? 409 LEU   B CD1 1 
ATOM   3032 C CD2 . LEU   B 1 194 ? 51.620 27.318 -20.109 1.00 72.48  ? 409 LEU   B CD2 1 
ATOM   3033 N N   . GLN   B 1 195 ? 48.038 24.971 -17.570 1.00 65.69  ? 410 GLN   B N   1 
ATOM   3034 C CA  . GLN   B 1 195 ? 47.505 25.340 -16.268 1.00 63.67  ? 410 GLN   B CA  1 
ATOM   3035 C C   . GLN   B 1 195 ? 48.653 25.719 -15.352 1.00 61.91  ? 410 GLN   B C   1 
ATOM   3036 O O   . GLN   B 1 195 ? 49.586 24.933 -15.158 1.00 60.47  ? 410 GLN   B O   1 
ATOM   3037 C CB  . GLN   B 1 195 ? 46.696 24.191 -15.666 1.00 60.98  ? 410 GLN   B CB  1 
ATOM   3038 C CG  . GLN   B 1 195 ? 45.225 24.395 -15.895 1.00 63.00  ? 410 GLN   B CG  1 
ATOM   3039 C CD  . GLN   B 1 195 ? 44.342 23.556 -15.001 1.00 63.13  ? 410 GLN   B CD  1 
ATOM   3040 O OE1 . GLN   B 1 195 ? 44.751 22.511 -14.475 1.00 60.40  ? 410 GLN   B OE1 1 
ATOM   3041 N NE2 . GLN   B 1 195 ? 43.105 24.003 -14.833 1.00 62.65  ? 410 GLN   B NE2 1 
ATOM   3042 N N   . VAL   B 1 196 ? 48.574 26.910 -14.772 1.00 64.75  ? 411 VAL   B N   1 
ATOM   3043 C CA  . VAL   B 1 196 ? 49.616 27.433 -13.892 1.00 64.18  ? 411 VAL   B CA  1 
ATOM   3044 C C   . VAL   B 1 196 ? 48.980 27.738 -12.550 1.00 66.33  ? 411 VAL   B C   1 
ATOM   3045 O O   . VAL   B 1 196 ? 48.074 28.574 -12.470 1.00 67.14  ? 411 VAL   B O   1 
ATOM   3046 C CB  . VAL   B 1 196 ? 50.287 28.684 -14.482 1.00 64.51  ? 411 VAL   B CB  1 
ATOM   3047 C CG1 . VAL   B 1 196 ? 51.413 29.158 -13.561 1.00 66.07  ? 411 VAL   B CG1 1 
ATOM   3048 C CG2 . VAL   B 1 196 ? 50.812 28.389 -15.886 1.00 62.54  ? 411 VAL   B CG2 1 
ATOM   3049 N N   . VAL   B 1 197 ? 49.443 27.059 -11.500 1.00 67.70  ? 412 VAL   B N   1 
ATOM   3050 C CA  . VAL   B 1 197 ? 48.992 27.306 -10.130 1.00 69.68  ? 412 VAL   B CA  1 
ATOM   3051 C C   . VAL   B 1 197 ? 50.119 28.017 -9.402  1.00 72.89  ? 412 VAL   B C   1 
ATOM   3052 O O   . VAL   B 1 197 ? 51.233 27.487 -9.288  1.00 72.35  ? 412 VAL   B O   1 
ATOM   3053 C CB  . VAL   B 1 197 ? 48.599 26.006 -9.404  1.00 68.65  ? 412 VAL   B CB  1 
ATOM   3054 C CG1 . VAL   B 1 197 ? 48.170 26.307 -7.971  1.00 70.47  ? 412 VAL   B CG1 1 
ATOM   3055 C CG2 . VAL   B 1 197 ? 47.471 25.312 -10.130 1.00 67.36  ? 412 VAL   B CG2 1 
ATOM   3056 N N   . THR   B 1 198 ? 49.836 29.217 -8.904  1.00 74.58  ? 413 THR   B N   1 
ATOM   3057 C CA  . THR   B 1 198 ? 50.860 30.024 -8.278  1.00 76.47  ? 413 THR   B CA  1 
ATOM   3058 C C   . THR   B 1 198 ? 50.393 30.409 -6.887  1.00 77.43  ? 413 THR   B C   1 
ATOM   3059 O O   . THR   B 1 198 ? 49.193 30.528 -6.626  1.00 76.19  ? 413 THR   B O   1 
ATOM   3060 C CB  . THR   B 1 198 ? 51.159 31.277 -9.092  1.00 77.75  ? 413 THR   B CB  1 
ATOM   3061 O OG1 . THR   B 1 198 ? 50.342 32.351 -8.618  1.00 79.20  ? 413 THR   B OG1 1 
ATOM   3062 C CG2 . THR   B 1 198 ? 50.817 31.054 -10.542 1.00 74.70  ? 413 THR   B CG2 1 
ATOM   3063 N N   . ASN   B 1 199 ? 51.358 30.597 -5.994  1.00 80.88  ? 414 ASN   B N   1 
ATOM   3064 C CA  . ASN   B 1 199 ? 51.101 31.142 -4.668  1.00 81.74  ? 414 ASN   B CA  1 
ATOM   3065 C C   . ASN   B 1 199 ? 50.745 32.613 -4.825  1.00 82.51  ? 414 ASN   B C   1 
ATOM   3066 O O   . ASN   B 1 199 ? 51.611 33.446 -5.106  1.00 85.09  ? 414 ASN   B O   1 
ATOM   3067 C CB  . ASN   B 1 199 ? 52.321 30.944 -3.778  1.00 86.48  ? 414 ASN   B CB  1 
ATOM   3068 C CG  . ASN   B 1 199 ? 52.053 31.313 -2.334  1.00 88.16  ? 414 ASN   B CG  1 
ATOM   3069 O OD1 . ASN   B 1 199 ? 51.253 32.202 -2.062  1.00 87.71  ? 414 ASN   B OD1 1 
ATOM   3070 N ND2 . ASN   B 1 199 ? 52.722 30.637 -1.401  1.00 90.30  ? 414 ASN   B ND2 1 
ATOM   3071 N N   . ARG   B 1 200 ? 49.464 32.948 -4.640  1.00 77.61  ? 415 ARG   B N   1 
ATOM   3072 C CA  . ARG   B 1 200 ? 49.017 34.282 -5.031  1.00 79.05  ? 415 ARG   B CA  1 
ATOM   3073 C C   . ARG   B 1 200 ? 49.743 35.372 -4.259  1.00 81.95  ? 415 ARG   B C   1 
ATOM   3074 O O   . ARG   B 1 200 ? 49.882 36.494 -4.760  1.00 83.84  ? 415 ARG   B O   1 
ATOM   3075 C CB  . ARG   B 1 200 ? 47.517 34.460 -4.822  1.00 76.75  ? 415 ARG   B CB  1 
ATOM   3076 C CG  . ARG   B 1 200 ? 47.150 35.929 -4.777  1.00 77.98  ? 415 ARG   B CG  1 
ATOM   3077 C CD  . ARG   B 1 200 ? 45.706 36.163 -4.430  1.00 80.17  ? 415 ARG   B CD  1 
ATOM   3078 N NE  . ARG   B 1 200 ? 45.477 36.440 -3.016  1.00 81.88  ? 415 ARG   B NE  1 
ATOM   3079 C CZ  . ARG   B 1 200 ? 44.360 37.013 -2.587  1.00 82.88  ? 415 ARG   B CZ  1 
ATOM   3080 N NH1 . ARG   B 1 200 ? 43.367 37.271 -3.432  1.00 82.00  ? 415 ARG   B NH1 1 
ATOM   3081 N NH2 . ARG   B 1 200 ? 44.244 37.357 -1.295  1.00 80.83  ? 415 ARG   B NH2 1 
ATOM   3082 N N   . ASP   B 1 201 ? 50.190 35.082 -3.035  1.00 83.10  ? 416 ASP   B N   1 
ATOM   3083 C CA  . ASP   B 1 201 ? 50.811 36.138 -2.240  1.00 86.10  ? 416 ASP   B CA  1 
ATOM   3084 C C   . ASP   B 1 201 ? 52.286 36.323 -2.574  1.00 88.37  ? 416 ASP   B C   1 
ATOM   3085 O O   . ASP   B 1 201 ? 52.833 37.415 -2.368  1.00 89.07  ? 416 ASP   B O   1 
ATOM   3086 C CB  . ASP   B 1 201 ? 50.646 35.875 -0.732  1.00 85.85  ? 416 ASP   B CB  1 
ATOM   3087 C CG  . ASP   B 1 201 ? 49.191 35.972 -0.265  1.00 85.16  ? 416 ASP   B CG  1 
ATOM   3088 O OD1 . ASP   B 1 201 ? 48.420 36.773 -0.849  1.00 83.64  ? 416 ASP   B OD1 1 
ATOM   3089 O OD2 . ASP   B 1 201 ? 48.836 35.308 0.739   1.00 84.26  ? 416 ASP   B OD2 1 
ATOM   3090 N N   . THR   B 1 202 ? 52.943 35.286 -3.086  1.00 90.29  ? 417 THR   B N   1 
ATOM   3091 C CA  . THR   B 1 202 ? 54.377 35.323 -3.339  1.00 93.32  ? 417 THR   B CA  1 
ATOM   3092 C C   . THR   B 1 202 ? 54.749 35.348 -4.816  1.00 93.20  ? 417 THR   B C   1 
ATOM   3093 O O   . THR   B 1 202 ? 55.877 35.732 -5.147  1.00 93.28  ? 417 THR   B O   1 
ATOM   3094 C CB  . THR   B 1 202 ? 55.053 34.120 -2.663  1.00 93.77  ? 417 THR   B CB  1 
ATOM   3095 O OG1 . THR   B 1 202 ? 54.504 32.917 -3.211  1.00 93.93  ? 417 THR   B OG1 1 
ATOM   3096 C CG2 . THR   B 1 202 ? 54.830 34.146 -1.156  1.00 91.63  ? 417 THR   B CG2 1 
ATOM   3097 N N   . GLN   B 1 203 ? 53.829 34.984 -5.703  1.00 92.07  ? 418 GLN   B N   1 
ATOM   3098 C CA  . GLN   B 1 203 ? 54.025 34.844 -7.135  1.00 91.68  ? 418 GLN   B CA  1 
ATOM   3099 C C   . GLN   B 1 203 ? 54.742 33.536 -7.459  1.00 90.20  ? 418 GLN   B C   1 
ATOM   3100 O O   . GLN   B 1 203 ? 54.845 33.192 -8.634  1.00 89.97  ? 418 GLN   B O   1 
ATOM   3101 C CB  . GLN   B 1 203 ? 54.802 36.020 -7.766  1.00 93.22  ? 418 GLN   B CB  1 
ATOM   3102 C CG  . GLN   B 1 203 ? 54.537 37.397 -7.132  1.00 97.64  ? 418 GLN   B CG  1 
ATOM   3103 C CD  . GLN   B 1 203 ? 53.139 37.912 -7.422  1.00 96.51  ? 418 GLN   B CD  1 
ATOM   3104 O OE1 . GLN   B 1 203 ? 52.436 37.380 -8.286  1.00 93.48  ? 418 GLN   B OE1 1 
ATOM   3105 N NE2 . GLN   B 1 203 ? 52.729 38.950 -6.704  1.00 94.17  ? 418 GLN   B NE2 1 
ATOM   3106 N N   . GLU   B 1 204 ? 55.237 32.795 -6.462  1.00 90.91  ? 419 GLU   B N   1 
ATOM   3107 C CA  . GLU   B 1 204 ? 55.833 31.489 -6.710  1.00 90.08  ? 419 GLU   B CA  1 
ATOM   3108 C C   . GLU   B 1 204 ? 54.948 30.662 -7.627  1.00 89.25  ? 419 GLU   B C   1 
ATOM   3109 O O   . GLU   B 1 204 ? 53.728 30.600 -7.451  1.00 88.11  ? 419 GLU   B O   1 
ATOM   3110 C CB  . GLU   B 1 204 ? 56.036 30.701 -5.407  1.00 90.50  ? 419 GLU   B CB  1 
ATOM   3111 C CG  . GLU   B 1 204 ? 56.680 31.422 -4.228  1.00 98.41  ? 419 GLU   B CG  1 
ATOM   3112 C CD  . GLU   B 1 204 ? 56.379 30.727 -2.882  1.00 105.45 ? 419 GLU   B CD  1 
ATOM   3113 O OE1 . GLU   B 1 204 ? 55.805 31.380 -1.975  1.00 109.54 ? 419 GLU   B OE1 1 
ATOM   3114 O OE2 . GLU   B 1 204 ? 56.707 29.525 -2.735  1.00 103.03 ? 419 GLU   B OE2 1 
ATOM   3115 N N   . LEU   B 1 205 ? 55.575 30.007 -8.600  1.00 84.25  ? 420 LEU   B N   1 
ATOM   3116 C CA  . LEU   B 1 205 ? 54.929 28.901 -9.294  1.00 80.64  ? 420 LEU   B CA  1 
ATOM   3117 C C   . LEU   B 1 205 ? 54.902 27.675 -8.383  1.00 78.55  ? 420 LEU   B C   1 
ATOM   3118 O O   . LEU   B 1 205 ? 55.915 27.323 -7.773  1.00 78.16  ? 420 LEU   B O   1 
ATOM   3119 C CB  . LEU   B 1 205 ? 55.661 28.591 -10.604 1.00 77.42  ? 420 LEU   B CB  1 
ATOM   3120 C CG  . LEU   B 1 205 ? 54.995 27.510 -11.450 1.00 74.99  ? 420 LEU   B CG  1 
ATOM   3121 C CD1 . LEU   B 1 205 ? 54.557 28.045 -12.804 1.00 75.01  ? 420 LEU   B CD1 1 
ATOM   3122 C CD2 . LEU   B 1 205 ? 55.950 26.348 -11.613 1.00 75.89  ? 420 LEU   B CD2 1 
ATOM   3123 N N   . LEU   B 1 206 ? 53.745 27.031 -8.275  1.00 75.85  ? 421 LEU   B N   1 
ATOM   3124 C CA  . LEU   B 1 206 ? 53.655 25.812 -7.485  1.00 78.57  ? 421 LEU   B CA  1 
ATOM   3125 C C   . LEU   B 1 206 ? 53.423 24.568 -8.326  1.00 74.07  ? 421 LEU   B C   1 
ATOM   3126 O O   . LEU   B 1 206 ? 53.897 23.487 -7.971  1.00 72.23  ? 421 LEU   B O   1 
ATOM   3127 C CB  . LEU   B 1 206 ? 52.530 25.928 -6.449  1.00 77.22  ? 421 LEU   B CB  1 
ATOM   3128 C CG  . LEU   B 1 206 ? 52.579 27.099 -5.463  1.00 79.09  ? 421 LEU   B CG  1 
ATOM   3129 C CD1 . LEU   B 1 206 ? 51.434 26.997 -4.480  1.00 79.67  ? 421 LEU   B CD1 1 
ATOM   3130 C CD2 . LEU   B 1 206 ? 53.897 27.116 -4.735  1.00 83.63  ? 421 LEU   B CD2 1 
ATOM   3131 N N   . LEU   B 1 207 ? 52.722 24.702 -9.441  1.00 73.08  ? 422 LEU   B N   1 
ATOM   3132 C CA  . LEU   B 1 207 ? 52.365 23.551 -10.249 1.00 69.78  ? 422 LEU   B CA  1 
ATOM   3133 C C   . LEU   B 1 207 ? 52.062 24.070 -11.638 1.00 66.54  ? 422 LEU   B C   1 
ATOM   3134 O O   . LEU   B 1 207 ? 51.282 25.015 -11.780 1.00 64.20  ? 422 LEU   B O   1 
ATOM   3135 C CB  . LEU   B 1 207 ? 51.150 22.834 -9.665  1.00 68.70  ? 422 LEU   B CB  1 
ATOM   3136 C CG  . LEU   B 1 207 ? 50.945 21.374 -10.016 1.00 66.23  ? 422 LEU   B CG  1 
ATOM   3137 C CD1 . LEU   B 1 207 ? 52.178 20.570 -9.658  1.00 68.38  ? 422 LEU   B CD1 1 
ATOM   3138 C CD2 . LEU   B 1 207 ? 49.755 20.887 -9.257  1.00 67.55  ? 422 LEU   B CD2 1 
ATOM   3139 N N   . CYS   B 1 208 ? 52.681 23.465 -12.648 1.00 67.13  ? 423 CYS   B N   1 
ATOM   3140 C CA  . CYS   B 1 208 ? 52.432 23.818 -14.041 1.00 64.59  ? 423 CYS   B CA  1 
ATOM   3141 C C   . CYS   B 1 208 ? 52.141 22.547 -14.821 1.00 64.39  ? 423 CYS   B C   1 
ATOM   3142 O O   . CYS   B 1 208 ? 52.993 21.659 -14.905 1.00 65.75  ? 423 CYS   B O   1 
ATOM   3143 C CB  . CYS   B 1 208 ? 53.622 24.565 -14.652 1.00 66.70  ? 423 CYS   B CB  1 
ATOM   3144 S SG  . CYS   B 1 208 ? 53.391 24.953 -16.410 1.00 62.10  ? 423 CYS   B SG  1 
ATOM   3145 N N   . THR   B 1 209 ? 50.943 22.462 -15.390 1.00 61.96  ? 424 THR   B N   1 
ATOM   3146 C CA  . THR   B 1 209 ? 50.496 21.290 -16.127 1.00 64.30  ? 424 THR   B CA  1 
ATOM   3147 C C   . THR   B 1 209 ? 50.211 21.673 -17.574 1.00 64.86  ? 424 THR   B C   1 
ATOM   3148 O O   . THR   B 1 209 ? 49.426 22.592 -17.838 1.00 60.96  ? 424 THR   B O   1 
ATOM   3149 C CB  . THR   B 1 209 ? 49.260 20.674 -15.474 1.00 62.96  ? 424 THR   B CB  1 
ATOM   3150 O OG1 . THR   B 1 209 ? 49.582 20.314 -14.126 1.00 59.76  ? 424 THR   B OG1 1 
ATOM   3151 C CG2 . THR   B 1 209 ? 48.844 19.417 -16.238 1.00 62.73  ? 424 THR   B CG2 1 
ATOM   3152 N N   . ALA   B 1 210 ? 50.848 20.965 -18.496 1.00 62.22  ? 425 ALA   B N   1 
ATOM   3153 C CA  . ALA   B 1 210 ? 50.596 21.089 -19.924 1.00 64.69  ? 425 ALA   B CA  1 
ATOM   3154 C C   . ALA   B 1 210 ? 49.729 19.921 -20.344 1.00 58.88  ? 425 ALA   B C   1 
ATOM   3155 O O   . ALA   B 1 210 ? 50.047 18.773 -20.033 1.00 58.53  ? 425 ALA   B O   1 
ATOM   3156 C CB  . ALA   B 1 210 ? 51.904 21.084 -20.719 1.00 67.29  ? 425 ALA   B CB  1 
ATOM   3157 N N   . TYR   B 1 211 ? 48.634 20.204 -21.031 1.00 61.50  ? 426 TYR   B N   1 
ATOM   3158 C CA  . TYR   B 1 211 ? 47.696 19.165 -21.425 1.00 59.69  ? 426 TYR   B CA  1 
ATOM   3159 C C   . TYR   B 1 211 ? 47.702 19.013 -22.937 1.00 61.03  ? 426 TYR   B C   1 
ATOM   3160 O O   . TYR   B 1 211 ? 47.558 20.003 -23.659 1.00 61.45  ? 426 TYR   B O   1 
ATOM   3161 C CB  . TYR   B 1 211 ? 46.285 19.491 -20.956 1.00 58.08  ? 426 TYR   B CB  1 
ATOM   3162 C CG  . TYR   B 1 211 ? 46.098 19.572 -19.449 1.00 59.80  ? 426 TYR   B CG  1 
ATOM   3163 C CD1 . TYR   B 1 211 ? 45.766 18.442 -18.696 1.00 57.53  ? 426 TYR   B CD1 1 
ATOM   3164 C CD2 . TYR   B 1 211 ? 46.210 20.771 -18.793 1.00 59.79  ? 426 TYR   B CD2 1 
ATOM   3165 C CE1 . TYR   B 1 211 ? 45.572 18.527 -17.320 1.00 58.35  ? 426 TYR   B CE1 1 
ATOM   3166 C CE2 . TYR   B 1 211 ? 46.013 20.860 -17.441 1.00 60.27  ? 426 TYR   B CE2 1 
ATOM   3167 C CZ  . TYR   B 1 211 ? 45.694 19.746 -16.702 1.00 59.55  ? 426 TYR   B CZ  1 
ATOM   3168 O OH  . TYR   B 1 211 ? 45.505 19.896 -15.332 1.00 61.08  ? 426 TYR   B OH  1 
ATOM   3169 N N   . VAL   B 1 212 ? 47.833 17.775 -23.410 1.00 58.42  ? 427 VAL   B N   1 
ATOM   3170 C CA  . VAL   B 1 212 ? 47.656 17.463 -24.823 1.00 59.05  ? 427 VAL   B CA  1 
ATOM   3171 C C   . VAL   B 1 212 ? 46.564 16.412 -24.924 1.00 60.01  ? 427 VAL   B C   1 
ATOM   3172 O O   . VAL   B 1 212 ? 46.265 15.714 -23.952 1.00 60.36  ? 427 VAL   B O   1 
ATOM   3173 C CB  . VAL   B 1 212 ? 48.963 17.007 -25.506 1.00 58.28  ? 427 VAL   B CB  1 
ATOM   3174 C CG1 . VAL   B 1 212 ? 50.020 18.091 -25.374 1.00 60.77  ? 427 VAL   B CG1 1 
ATOM   3175 C CG2 . VAL   B 1 212 ? 49.470 15.728 -24.931 1.00 59.90  ? 427 VAL   B CG2 1 
ATOM   3176 N N   . PHE   B 1 213 ? 45.949 16.314 -26.107 1.00 56.98  ? 428 PHE   B N   1 
ATOM   3177 C CA  . PHE   B 1 213 ? 44.689 15.594 -26.273 1.00 59.84  ? 428 PHE   B CA  1 
ATOM   3178 C C   . PHE   B 1 213 ? 44.698 14.674 -27.492 1.00 61.38  ? 428 PHE   B C   1 
ATOM   3179 O O   . PHE   B 1 213 ? 45.378 14.932 -28.480 1.00 60.93  ? 428 PHE   B O   1 
ATOM   3180 C CB  . PHE   B 1 213 ? 43.539 16.585 -26.393 1.00 57.97  ? 428 PHE   B CB  1 
ATOM   3181 C CG  . PHE   B 1 213 ? 43.396 17.478 -25.187 1.00 62.66  ? 428 PHE   B CG  1 
ATOM   3182 C CD1 . PHE   B 1 213 ? 44.117 18.654 -25.084 1.00 59.73  ? 428 PHE   B CD1 1 
ATOM   3183 C CD2 . PHE   B 1 213 ? 42.553 17.126 -24.140 1.00 60.47  ? 428 PHE   B CD2 1 
ATOM   3184 C CE1 . PHE   B 1 213 ? 43.995 19.453 -23.965 1.00 62.57  ? 428 PHE   B CE1 1 
ATOM   3185 C CE2 . PHE   B 1 213 ? 42.433 17.938 -23.036 1.00 59.00  ? 428 PHE   B CE2 1 
ATOM   3186 C CZ  . PHE   B 1 213 ? 43.151 19.087 -22.944 1.00 59.14  ? 428 PHE   B CZ  1 
ATOM   3187 N N   . GLU   B 1 214 ? 43.978 13.561 -27.369 1.00 61.80  ? 429 GLU   B N   1 
ATOM   3188 C CA  . GLU   B 1 214 ? 43.442 12.766 -28.464 1.00 62.22  ? 429 GLU   B CA  1 
ATOM   3189 C C   . GLU   B 1 214 ? 42.014 12.423 -28.063 1.00 62.15  ? 429 GLU   B C   1 
ATOM   3190 O O   . GLU   B 1 214 ? 41.588 12.723 -26.943 1.00 59.98  ? 429 GLU   B O   1 
ATOM   3191 C CB  . GLU   B 1 214 ? 44.249 11.484 -28.707 1.00 61.43  ? 429 GLU   B CB  1 
ATOM   3192 C CG  . GLU   B 1 214 ? 45.651 11.728 -29.173 1.00 63.38  ? 429 GLU   B CG  1 
ATOM   3193 C CD  . GLU   B 1 214 ? 46.349 10.440 -29.497 1.00 66.14  ? 429 GLU   B CD  1 
ATOM   3194 O OE1 . GLU   B 1 214 ? 45.671 9.374  -29.511 1.00 67.38  ? 429 GLU   B OE1 1 
ATOM   3195 O OE2 . GLU   B 1 214 ? 47.578 10.472 -29.750 1.00 69.88  ? 429 GLU   B OE2 1 
ATOM   3196 N N   . VAL   B 1 215 ? 41.269 11.751 -28.945 1.00 59.95  ? 430 VAL   B N   1 
ATOM   3197 C CA  . VAL   B 1 215 ? 39.955 11.244 -28.566 1.00 63.37  ? 430 VAL   B CA  1 
ATOM   3198 C C   . VAL   B 1 215 ? 40.057 9.763  -28.307 1.00 66.15  ? 430 VAL   B C   1 
ATOM   3199 O O   . VAL   B 1 215 ? 40.792 9.034  -28.987 1.00 67.47  ? 430 VAL   B O   1 
ATOM   3200 C CB  . VAL   B 1 215 ? 38.853 11.509 -29.601 1.00 62.16  ? 430 VAL   B CB  1 
ATOM   3201 C CG1 . VAL   B 1 215 ? 38.660 13.012 -29.795 1.00 62.06  ? 430 VAL   B CG1 1 
ATOM   3202 C CG2 . VAL   B 1 215 ? 39.168 10.761 -30.895 1.00 66.06  ? 430 VAL   B CG2 1 
ATOM   3203 N N   . SER   B 1 216 ? 39.310 9.320  -27.323 1.00 67.98  ? 431 SER   B N   1 
ATOM   3204 C CA  . SER   B 1 216 ? 39.172 7.907  -27.069 1.00 72.55  ? 431 SER   B CA  1 
ATOM   3205 C C   . SER   B 1 216 ? 37.962 7.389  -27.837 1.00 76.57  ? 431 SER   B C   1 
ATOM   3206 O O   . SER   B 1 216 ? 37.077 8.144  -28.245 1.00 77.18  ? 431 SER   B O   1 
ATOM   3207 C CB  . SER   B 1 216 ? 39.025 7.654  -25.570 1.00 71.64  ? 431 SER   B CB  1 
ATOM   3208 O OG  . SER   B 1 216 ? 38.505 6.365  -25.356 1.00 73.24  ? 431 SER   B OG  1 
ATOM   3209 N N   . THR   B 1 217 ? 37.928 6.084  -28.024 1.00 80.13  ? 432 THR   B N   1 
ATOM   3210 C CA  . THR   B 1 217 ? 36.890 5.460  -28.829 1.00 86.73  ? 432 THR   B CA  1 
ATOM   3211 C C   . THR   B 1 217 ? 35.558 5.423  -28.061 1.00 90.54  ? 432 THR   B C   1 
ATOM   3212 O O   . THR   B 1 217 ? 35.440 5.900  -26.927 1.00 87.85  ? 432 THR   B O   1 
ATOM   3213 C CB  . THR   B 1 217 ? 37.364 4.074  -29.241 1.00 86.33  ? 432 THR   B CB  1 
ATOM   3214 O OG1 . THR   B 1 217 ? 37.011 3.138  -28.211 1.00 88.02  ? 432 THR   B OG1 1 
ATOM   3215 C CG2 . THR   B 1 217 ? 38.873 4.094  -29.379 1.00 81.37  ? 432 THR   B CG2 1 
ATOM   3216 N N   . SER   B 1 218 ? 34.527 4.870  -28.697 1.00 108.42 ? 433 SER   B N   1 
ATOM   3217 C CA  . SER   B 1 218 ? 33.213 4.813  -28.070 1.00 108.84 ? 433 SER   B CA  1 
ATOM   3218 C C   . SER   B 1 218 ? 33.268 3.984  -26.798 1.00 107.73 ? 433 SER   B C   1 
ATOM   3219 O O   . SER   B 1 218 ? 33.068 4.502  -25.693 1.00 106.42 ? 433 SER   B O   1 
ATOM   3220 C CB  . SER   B 1 218 ? 32.174 4.220  -29.027 1.00 111.67 ? 433 SER   B CB  1 
ATOM   3221 O OG  . SER   B 1 218 ? 31.802 5.150  -30.027 1.00 120.52 ? 433 SER   B OG  1 
ATOM   3222 N N   . GLU   B 1 219 ? 33.547 2.692  -26.966 1.00 96.55  ? 434 GLU   B N   1 
ATOM   3223 C CA  . GLU   B 1 219 ? 33.504 1.728  -25.880 1.00 90.50  ? 434 GLU   B CA  1 
ATOM   3224 C C   . GLU   B 1 219 ? 34.549 1.984  -24.806 1.00 86.96  ? 434 GLU   B C   1 
ATOM   3225 O O   . GLU   B 1 219 ? 34.457 1.373  -23.733 1.00 87.00  ? 434 GLU   B O   1 
ATOM   3226 C CB  . GLU   B 1 219 ? 33.684 0.316  -26.434 1.00 89.43  ? 434 GLU   B CB  1 
ATOM   3227 C CG  . GLU   B 1 219 ? 34.589 0.249  -27.643 1.00 91.58  ? 434 GLU   B CG  1 
ATOM   3228 C CD  . GLU   B 1 219 ? 34.666 -1.136 -28.253 1.00 91.65  ? 434 GLU   B CD  1 
ATOM   3229 O OE1 . GLU   B 1 219 ? 33.833 -2.016 -27.921 1.00 89.52  ? 434 GLU   B OE1 1 
ATOM   3230 O OE2 . GLU   B 1 219 ? 35.591 -1.333 -29.075 1.00 95.93  ? 434 GLU   B OE2 1 
ATOM   3231 N N   . ARG   B 1 220 ? 35.527 2.845  -25.055 1.00 80.58  ? 435 ARG   B N   1 
ATOM   3232 C CA  . ARG   B 1 220 ? 36.546 3.180  -24.077 1.00 75.41  ? 435 ARG   B CA  1 
ATOM   3233 C C   . ARG   B 1 220 ? 36.304 4.591  -23.563 1.00 76.35  ? 435 ARG   B C   1 
ATOM   3234 O O   . ARG   B 1 220 ? 36.087 5.528  -24.346 1.00 78.07  ? 435 ARG   B O   1 
ATOM   3235 C CB  . ARG   B 1 220 ? 37.950 3.099  -24.677 1.00 72.16  ? 435 ARG   B CB  1 
ATOM   3236 C CG  . ARG   B 1 220 ? 38.337 1.759  -25.256 1.00 72.93  ? 435 ARG   B CG  1 
ATOM   3237 C CD  . ARG   B 1 220 ? 39.766 1.846  -25.785 1.00 71.85  ? 435 ARG   B CD  1 
ATOM   3238 N NE  . ARG   B 1 220 ? 40.741 1.916  -24.697 1.00 70.45  ? 435 ARG   B NE  1 
ATOM   3239 C CZ  . ARG   B 1 220 ? 42.018 1.559  -24.801 1.00 69.07  ? 435 ARG   B CZ  1 
ATOM   3240 N NH1 . ARG   B 1 220 ? 42.531 1.155  -25.961 1.00 70.08  ? 435 ARG   B NH1 1 
ATOM   3241 N NH2 . ARG   B 1 220 ? 42.798 1.612  -23.718 1.00 67.96  ? 435 ARG   B NH2 1 
ATOM   3242 N N   . GLY   B 1 221 ? 36.381 4.754  -22.253 1.00 72.23  ? 436 GLY   B N   1 
ATOM   3243 C CA  . GLY   B 1 221 ? 36.186 6.043  -21.645 1.00 72.44  ? 436 GLY   B CA  1 
ATOM   3244 C C   . GLY   B 1 221 ? 37.473 6.825  -21.556 1.00 70.59  ? 436 GLY   B C   1 
ATOM   3245 O O   . GLY   B 1 221 ? 38.512 6.447  -22.096 1.00 69.25  ? 436 GLY   B O   1 
ATOM   3246 N N   . ALA   B 1 222 ? 37.397 7.929  -20.829 1.00 66.60  ? 437 ALA   B N   1 
ATOM   3247 C CA  . ALA   B 1 222 ? 38.548 8.797  -20.683 1.00 65.79  ? 437 ALA   B CA  1 
ATOM   3248 C C   . ALA   B 1 222 ? 39.699 8.057  -20.021 1.00 64.19  ? 437 ALA   B C   1 
ATOM   3249 O O   . ALA   B 1 222 ? 39.498 7.208  -19.164 1.00 66.88  ? 437 ALA   B O   1 
ATOM   3250 C CB  . ALA   B 1 222 ? 38.162 10.028 -19.867 1.00 64.87  ? 437 ALA   B CB  1 
ATOM   3251 N N   . GLN   B 1 223 ? 40.914 8.373  -20.435 1.00 64.07  ? 438 GLN   B N   1 
ATOM   3252 C CA  . GLN   B 1 223 ? 42.097 7.829  -19.808 1.00 62.30  ? 438 GLN   B CA  1 
ATOM   3253 C C   . GLN   B 1 223 ? 43.136 8.932  -19.861 1.00 63.15  ? 438 GLN   B C   1 
ATOM   3254 O O   . GLN   B 1 223 ? 42.995 9.914  -20.602 1.00 61.08  ? 438 GLN   B O   1 
ATOM   3255 C CB  . GLN   B 1 223 ? 42.596 6.577  -20.550 1.00 64.39  ? 438 GLN   B CB  1 
ATOM   3256 C CG  . GLN   B 1 223 ? 43.266 5.464  -19.695 1.00 67.26  ? 438 GLN   B CG  1 
ATOM   3257 C CD  . GLN   B 1 223 ? 43.115 4.090  -20.334 1.00 69.20  ? 438 GLN   B CD  1 
ATOM   3258 O OE1 . GLN   B 1 223 ? 43.334 3.049  -19.700 1.00 70.50  ? 438 GLN   B OE1 1 
ATOM   3259 N NE2 . GLN   B 1 223 ? 42.757 4.080  -21.627 1.00 69.59  ? 438 GLN   B NE2 1 
ATOM   3260 N N   . HIS   B 1 224 ? 44.188 8.782  -19.074 1.00 59.33  ? 439 HIS   B N   1 
ATOM   3261 C CA  . HIS   B 1 224 ? 45.220 9.801  -19.091 1.00 61.39  ? 439 HIS   B CA  1 
ATOM   3262 C C   . HIS   B 1 224 ? 46.538 9.131  -18.779 1.00 62.31  ? 439 HIS   B C   1 
ATOM   3263 O O   . HIS   B 1 224 ? 46.587 7.971  -18.398 1.00 64.23  ? 439 HIS   B O   1 
ATOM   3264 C CB  . HIS   B 1 224 ? 44.922 10.917 -18.088 1.00 61.49  ? 439 HIS   B CB  1 
ATOM   3265 C CG  . HIS   B 1 224 ? 44.725 10.404 -16.708 1.00 62.47  ? 439 HIS   B CG  1 
ATOM   3266 N ND1 . HIS   B 1 224 ? 45.777 9.971  -15.935 1.00 62.81  ? 439 HIS   B ND1 1 
ATOM   3267 C CD2 . HIS   B 1 224 ? 43.601 10.158 -15.996 1.00 61.89  ? 439 HIS   B CD2 1 
ATOM   3268 C CE1 . HIS   B 1 224 ? 45.313 9.512  -14.785 1.00 62.57  ? 439 HIS   B CE1 1 
ATOM   3269 N NE2 . HIS   B 1 224 ? 43.995 9.616  -14.799 1.00 62.22  ? 439 HIS   B NE2 1 
ATOM   3270 N N   . HIS   B 1 225 ? 47.614 9.870  -18.990 1.00 63.80  ? 440 HIS   B N   1 
ATOM   3271 C CA  . HIS   B 1 225 ? 48.961 9.398  -18.705 1.00 67.74  ? 440 HIS   B CA  1 
ATOM   3272 C C   . HIS   B 1 225 ? 49.712 10.649 -18.289 1.00 69.19  ? 440 HIS   B C   1 
ATOM   3273 O O   . HIS   B 1 225 ? 49.797 11.597 -19.079 1.00 65.46  ? 440 HIS   B O   1 
ATOM   3274 C CB  . HIS   B 1 225 ? 49.603 8.740  -19.937 1.00 68.84  ? 440 HIS   B CB  1 
ATOM   3275 C CG  . HIS   B 1 225 ? 50.774 7.849  -19.632 1.00 72.31  ? 440 HIS   B CG  1 
ATOM   3276 N ND1 . HIS   B 1 225 ? 51.833 8.246  -18.845 1.00 72.95  ? 440 HIS   B ND1 1 
ATOM   3277 C CD2 . HIS   B 1 225 ? 51.080 6.602  -20.061 1.00 74.68  ? 440 HIS   B CD2 1 
ATOM   3278 C CE1 . HIS   B 1 225 ? 52.722 7.273  -18.771 1.00 75.50  ? 440 HIS   B CE1 1 
ATOM   3279 N NE2 . HIS   B 1 225 ? 52.291 6.264  -19.504 1.00 76.84  ? 440 HIS   B NE2 1 
ATOM   3280 N N   . ILE   B 1 226 ? 50.198 10.672 -17.046 1.00 67.89  ? 441 ILE   B N   1 
ATOM   3281 C CA  . ILE   B 1 226 ? 50.920 11.807 -16.502 1.00 68.99  ? 441 ILE   B CA  1 
ATOM   3282 C C   . ILE   B 1 226 ? 52.409 11.574 -16.654 1.00 69.56  ? 441 ILE   B C   1 
ATOM   3283 O O   . ILE   B 1 226 ? 52.912 10.493 -16.352 1.00 72.76  ? 441 ILE   B O   1 
ATOM   3284 C CB  . ILE   B 1 226 ? 50.561 12.055 -15.028 1.00 70.86  ? 441 ILE   B CB  1 
ATOM   3285 C CG1 . ILE   B 1 226 ? 49.056 12.281 -14.853 1.00 67.45  ? 441 ILE   B CG1 1 
ATOM   3286 C CG2 . ILE   B 1 226 ? 51.329 13.262 -14.509 1.00 70.91  ? 441 ILE   B CG2 1 
ATOM   3287 C CD1 . ILE   B 1 226 ? 48.523 11.826 -13.480 1.00 67.11  ? 441 ILE   B CD1 1 
ATOM   3288 N N   . TYR   B 1 227 ? 53.121 12.590 -17.133 1.00 70.91  ? 442 TYR   B N   1 
ATOM   3289 C CA  . TYR   B 1 227 ? 54.569 12.526 -17.244 1.00 70.03  ? 442 TYR   B CA  1 
ATOM   3290 C C   . TYR   B 1 227 ? 55.196 13.651 -16.435 1.00 70.38  ? 442 TYR   B C   1 
ATOM   3291 O O   . TYR   B 1 227 ? 54.576 14.686 -16.191 1.00 69.76  ? 442 TYR   B O   1 
ATOM   3292 C CB  . TYR   B 1 227 ? 55.045 12.629 -18.694 1.00 71.02  ? 442 TYR   B CB  1 
ATOM   3293 C CG  . TYR   B 1 227 ? 54.500 11.575 -19.638 1.00 72.30  ? 442 TYR   B CG  1 
ATOM   3294 C CD1 . TYR   B 1 227 ? 53.254 11.715 -20.236 1.00 70.76  ? 442 TYR   B CD1 1 
ATOM   3295 C CD2 . TYR   B 1 227 ? 55.236 10.447 -19.931 1.00 74.94  ? 442 TYR   B CD2 1 
ATOM   3296 C CE1 . TYR   B 1 227 ? 52.764 10.753 -21.101 1.00 70.84  ? 442 TYR   B CE1 1 
ATOM   3297 C CE2 . TYR   B 1 227 ? 54.753 9.483  -20.788 1.00 76.21  ? 442 TYR   B CE2 1 
ATOM   3298 C CZ  . TYR   B 1 227 ? 53.512 9.643  -21.369 1.00 73.67  ? 442 TYR   B CZ  1 
ATOM   3299 O OH  . TYR   B 1 227 ? 53.042 8.674  -22.232 1.00 76.23  ? 442 TYR   B OH  1 
ATOM   3300 N N   . ARG   B 1 228 ? 56.447 13.445 -16.040 1.00 72.18  ? 443 ARG   B N   1 
ATOM   3301 C CA  . ARG   B 1 228 ? 57.273 14.516 -15.501 1.00 73.63  ? 443 ARG   B CA  1 
ATOM   3302 C C   . ARG   B 1 228 ? 57.984 15.222 -16.652 1.00 75.92  ? 443 ARG   B C   1 
ATOM   3303 O O   . ARG   B 1 228 ? 58.653 14.569 -17.457 1.00 77.46  ? 443 ARG   B O   1 
ATOM   3304 C CB  . ARG   B 1 228 ? 58.307 13.956 -14.526 1.00 75.68  ? 443 ARG   B CB  1 
ATOM   3305 C CG  . ARG   B 1 228 ? 57.933 14.021 -13.069 1.00 76.98  ? 443 ARG   B CG  1 
ATOM   3306 C CD  . ARG   B 1 228 ? 59.032 13.379 -12.222 1.00 82.59  ? 443 ARG   B CD  1 
ATOM   3307 N NE  . ARG   B 1 228 ? 59.381 12.038 -12.686 1.00 84.86  ? 443 ARG   B NE  1 
ATOM   3308 C CZ  . ARG   B 1 228 ? 60.533 11.716 -13.264 1.00 83.99  ? 443 ARG   B CZ  1 
ATOM   3309 N NH1 . ARG   B 1 228 ? 61.494 12.609 -13.439 1.00 86.05  ? 443 ARG   B NH1 1 
ATOM   3310 N NH2 . ARG   B 1 228 ? 60.727 10.467 -13.682 1.00 84.39  ? 443 ARG   B NH2 1 
ATOM   3311 N N   . LEU   B 1 229 ? 57.844 16.548 -16.731 1.00 76.91  ? 444 LEU   B N   1 
ATOM   3312 C CA  . LEU   B 1 229 ? 58.577 17.336 -17.718 1.00 81.61  ? 444 LEU   B CA  1 
ATOM   3313 C C   . LEU   B 1 229 ? 59.974 17.644 -17.193 1.00 85.76  ? 444 LEU   B C   1 
ATOM   3314 O O   . LEU   B 1 229 ? 60.127 18.309 -16.157 1.00 85.71  ? 444 LEU   B O   1 
ATOM   3315 C CB  . LEU   B 1 229 ? 57.844 18.632 -18.055 1.00 80.23  ? 444 LEU   B CB  1 
ATOM   3316 C CG  . LEU   B 1 229 ? 56.621 18.587 -18.972 1.00 78.40  ? 444 LEU   B CG  1 
ATOM   3317 C CD1 . LEU   B 1 229 ? 56.052 19.979 -19.153 1.00 76.91  ? 444 LEU   B CD1 1 
ATOM   3318 C CD2 . LEU   B 1 229 ? 56.927 17.948 -20.333 1.00 80.28  ? 444 LEU   B CD2 1 
ATOM   3319 N N   . VAL   B 1 230 ? 60.988 17.181 -17.934 1.00 86.16  ? 445 VAL   B N   1 
ATOM   3320 C CA  . VAL   B 1 230 ? 62.400 17.307 -17.594 1.00 88.54  ? 445 VAL   B CA  1 
ATOM   3321 C C   . VAL   B 1 230 ? 63.124 17.954 -18.770 1.00 93.43  ? 445 VAL   B C   1 
ATOM   3322 O O   . VAL   B 1 230 ? 62.601 18.036 -19.881 1.00 92.37  ? 445 VAL   B O   1 
ATOM   3323 C CB  . VAL   B 1 230 ? 63.040 15.944 -17.266 1.00 90.30  ? 445 VAL   B CB  1 
ATOM   3324 C CG1 . VAL   B 1 230 ? 62.353 15.306 -16.075 1.00 83.64  ? 445 VAL   B CG1 1 
ATOM   3325 C CG2 . VAL   B 1 230 ? 62.961 15.033 -18.478 1.00 89.88  ? 445 VAL   B CG2 1 
ATOM   3326 N N   . ARG   B 1 231 ? 64.361 18.399 -18.518 1.00 96.06  ? 446 ARG   B N   1 
ATOM   3327 C CA  . ARG   B 1 231 ? 65.170 19.055 -19.546 1.00 100.63 ? 446 ARG   B CA  1 
ATOM   3328 C C   . ARG   B 1 231 ? 66.636 18.760 -19.233 1.00 109.74 ? 446 ARG   B C   1 
ATOM   3329 O O   . ARG   B 1 231 ? 67.425 19.619 -18.845 1.00 112.82 ? 446 ARG   B O   1 
ATOM   3330 C CB  . ARG   B 1 231 ? 64.903 20.560 -19.608 1.00 99.76  ? 446 ARG   B CB  1 
ATOM   3331 C CG  . ARG   B 1 231 ? 65.826 21.314 -20.546 1.00 104.75 ? 446 ARG   B CG  1 
ATOM   3332 C CD  . ARG   B 1 231 ? 65.307 22.722 -20.701 1.00 102.68 ? 446 ARG   B CD  1 
ATOM   3333 N NE  . ARG   B 1 231 ? 65.556 23.517 -19.505 1.00 101.80 ? 446 ARG   B NE  1 
ATOM   3334 C CZ  . ARG   B 1 231 ? 65.183 24.782 -19.364 1.00 102.89 ? 446 ARG   B CZ  1 
ATOM   3335 N NH1 . ARG   B 1 231 ? 64.522 25.419 -20.318 1.00 103.84 ? 446 ARG   B NH1 1 
ATOM   3336 N NH2 . ARG   B 1 231 ? 65.452 25.414 -18.225 1.00 102.39 ? 446 ARG   B NH2 1 
ATOM   3337 N N   . ASP   B 1 232 ? 67.008 17.502 -19.412 1.00 118.13 ? 447 ASP   B N   1 
ATOM   3338 C CA  . ASP   B 1 232 ? 68.351 17.035 -19.109 1.00 120.69 ? 447 ASP   B CA  1 
ATOM   3339 C C   . ASP   B 1 232 ? 69.394 17.659 -20.033 1.00 124.41 ? 447 ASP   B C   1 
ATOM   3340 O O   . ASP   B 1 232 ? 69.213 18.769 -20.532 1.00 124.65 ? 447 ASP   B O   1 
ATOM   3341 C CB  . ASP   B 1 232 ? 68.396 15.515 -19.222 1.00 121.01 ? 447 ASP   B CB  1 
ATOM   3342 C CG  . ASP   B 1 232 ? 67.014 14.894 -19.158 1.00 121.08 ? 447 ASP   B CG  1 
ATOM   3343 O OD1 . ASP   B 1 232 ? 66.338 14.839 -20.213 1.00 119.80 ? 447 ASP   B OD1 1 
ATOM   3344 O OD2 . ASP   B 1 232 ? 66.602 14.477 -18.054 1.00 119.90 ? 447 ASP   B OD2 1 
HETATM 3345 C C13 . A1H3W C 2 .   ? 42.965 46.992 -17.395 0.90 65.67  ? 501 A1H3W A C13 1 
HETATM 3346 C C17 . A1H3W C 2 .   ? 44.781 49.613 -20.741 0.90 61.36  ? 501 A1H3W A C17 1 
HETATM 3347 C C20 . A1H3W C 2 .   ? 44.639 49.571 -23.596 0.90 61.29  ? 501 A1H3W A C20 1 
HETATM 3348 C C21 . A1H3W C 2 .   ? 45.100 50.685 -22.913 0.90 61.68  ? 501 A1H3W A C21 1 
HETATM 3349 C C22 . A1H3W C 2 .   ? 45.168 50.698 -21.504 0.90 62.93  ? 501 A1H3W A C22 1 
HETATM 3350 C C24 . A1H3W C 2 .   ? 41.201 49.196 -17.671 0.90 63.81  ? 501 A1H3W A C24 1 
HETATM 3351 C C01 . A1H3W C 2 .   ? 42.783 42.812 -13.590 0.90 73.01  ? 501 A1H3W A C01 1 
HETATM 3352 C C06 . A1H3W C 2 .   ? 42.387 43.949 -16.145 0.90 71.71  ? 501 A1H3W A C06 1 
HETATM 3353 C C07 . A1H3W C 2 .   ? 41.147 44.642 -15.513 0.90 69.27  ? 501 A1H3W A C07 1 
HETATM 3354 C C08 . A1H3W C 2 .   ? 40.881 46.003 -15.996 0.90 67.35  ? 501 A1H3W A C08 1 
HETATM 3355 C C09 . A1H3W C 2 .   ? 39.653 46.635 -15.763 0.90 66.55  ? 501 A1H3W A C09 1 
HETATM 3356 C C11 . A1H3W C 2 .   ? 40.833 48.078 -16.982 0.90 64.86  ? 501 A1H3W A C11 1 
HETATM 3357 C C12 . A1H3W C 2 .   ? 41.687 46.933 -16.801 0.90 64.77  ? 501 A1H3W A C12 1 
HETATM 3358 C C14 . A1H3W C 2 .   ? 43.330 48.142 -18.111 0.90 65.26  ? 501 A1H3W A C14 1 
HETATM 3359 C C16 . A1H3W C 2 .   ? 44.827 49.560 -19.218 0.90 64.36  ? 501 A1H3W A C16 1 
HETATM 3360 C C18 . A1H3W C 2 .   ? 44.294 48.504 -21.442 0.90 62.19  ? 501 A1H3W A C18 1 
HETATM 3361 C C19 . A1H3W C 2 .   ? 44.227 48.475 -22.834 0.90 62.81  ? 501 A1H3W A C19 1 
HETATM 3362 C C23 . A1H3W C 2 .   ? 42.410 49.210 -18.223 0.90 63.95  ? 501 A1H3W A C23 1 
HETATM 3363 N N05 . A1H3W C 2 .   ? 42.380 42.472 -16.090 0.90 74.25  ? 501 A1H3W A N05 1 
HETATM 3364 N N10 . A1H3W C 2 .   ? 39.642 47.882 -16.359 0.90 65.15  ? 501 A1H3W A N10 1 
HETATM 3365 O O03 . A1H3W C 2 .   ? 42.764 40.454 -14.700 0.90 79.66  ? 501 A1H3W A O03 1 
HETATM 3366 O O04 . A1H3W C 2 .   ? 44.529 41.984 -15.387 0.90 79.08  ? 501 A1H3W A O04 1 
HETATM 3367 O O15 . A1H3W C 2 .   ? 44.581 48.248 -18.728 0.90 63.95  ? 501 A1H3W A O15 1 
HETATM 3368 S S02 . A1H3W C 2 .   ? 43.194 41.791 -14.944 0.90 79.49  ? 501 A1H3W A S02 1 
HETATM 3369 H H1  . A1H3W C 2 .   ? 43.538 46.267 -17.298 0.90 78.81  ? 501 A1H3W A H1  1 
HETATM 3370 H H2  . A1H3W C 2 .   ? 44.607 49.555 -24.524 0.90 73.55  ? 501 A1H3W A H2  1 
HETATM 3371 H H3  . A1H3W C 2 .   ? 45.365 51.428 -23.404 0.90 74.02  ? 501 A1H3W A H3  1 
HETATM 3372 H H4  . A1H3W C 2 .   ? 45.485 51.467 -21.091 0.90 75.52  ? 501 A1H3W A H4  1 
HETATM 3373 H H5  . A1H3W C 2 .   ? 40.625 49.920 -17.750 0.90 76.58  ? 501 A1H3W A H5  1 
HETATM 3374 H H6  . A1H3W C 2 .   ? 43.236 43.627 -13.478 0.90 87.61  ? 501 A1H3W A H6  1 
HETATM 3375 H H7  . A1H3W C 2 .   ? 41.904 43.133 -13.510 0.90 87.61  ? 501 A1H3W A H7  1 
HETATM 3376 H H8  . A1H3W C 2 .   ? 42.885 42.479 -12.718 0.90 87.61  ? 501 A1H3W A H8  1 
HETATM 3377 H H9  . A1H3W C 2 .   ? 43.163 44.277 -15.732 0.90 86.05  ? 501 A1H3W A H9  1 
HETATM 3378 H H10 . A1H3W C 2 .   ? 42.474 44.232 -17.036 0.90 86.05  ? 501 A1H3W A H10 1 
HETATM 3379 H H11 . A1H3W C 2 .   ? 40.380 44.117 -15.648 0.90 83.13  ? 501 A1H3W A H11 1 
HETATM 3380 H H12 . A1H3W C 2 .   ? 41.231 44.663 -14.578 0.90 83.13  ? 501 A1H3W A H12 1 
HETATM 3381 H H13 . A1H3W C 2 .   ? 38.903 46.347 -15.296 0.90 79.86  ? 501 A1H3W A H13 1 
HETATM 3382 H H14 . A1H3W C 2 .   ? 45.665 49.856 -18.914 0.90 77.24  ? 501 A1H3W A H14 1 
HETATM 3383 H H15 . A1H3W C 2 .   ? 44.193 50.153 -18.859 0.90 77.24  ? 501 A1H3W A H15 1 
HETATM 3384 H H16 . A1H3W C 2 .   ? 43.993 47.737 -21.014 0.90 74.63  ? 501 A1H3W A H16 1 
HETATM 3385 H H17 . A1H3W C 2 .   ? 43.909 47.732 -23.293 0.90 75.38  ? 501 A1H3W A H17 1 
HETATM 3386 H H18 . A1H3W C 2 .   ? 42.663 49.962 -18.708 0.90 76.74  ? 501 A1H3W A H18 1 
HETATM 3387 H H19 . A1H3W C 2 .   ? 41.920 42.064 -16.702 0.90 89.10  ? 501 A1H3W A H19 1 
HETATM 3388 H H20 . A1H3W C 2 .   ? 38.974 48.435 -16.329 0.90 78.18  ? 501 A1H3W A H20 1 
HETATM 3389 C C13 . A1H3W D 2 .   ? 39.428 21.713 -19.471 1.00 59.10  ? 501 A1H3W B C13 1 
HETATM 3390 C C17 . A1H3W D 2 .   ? 38.269 18.853 -22.938 1.00 60.47  ? 501 A1H3W B C17 1 
HETATM 3391 C C20 . A1H3W D 2 .   ? 38.925 18.490 -25.705 1.00 60.99  ? 501 A1H3W B C20 1 
HETATM 3392 C C21 . A1H3W D 2 .   ? 38.999 19.755 -25.074 1.00 60.62  ? 501 A1H3W B C21 1 
HETATM 3393 C C22 . A1H3W D 2 .   ? 38.679 19.917 -23.720 1.00 61.33  ? 501 A1H3W B C22 1 
HETATM 3394 C C24 . A1H3W D 2 .   ? 41.414 19.684 -19.635 1.00 61.63  ? 501 A1H3W B C24 1 
HETATM 3395 C C01 . A1H3W D 2 .   ? 37.843 27.990 -17.268 1.00 71.53  ? 501 A1H3W B C01 1 
HETATM 3396 C C06 . A1H3W D 2 .   ? 39.652 24.819 -18.480 1.00 64.20  ? 501 A1H3W B C06 1 
HETATM 3397 C C07 . A1H3W D 2 .   ? 40.753 24.265 -17.554 1.00 62.92  ? 501 A1H3W B C07 1 
HETATM 3398 C C08 . A1H3W D 2 .   ? 41.284 22.957 -17.998 1.00 61.81  ? 501 A1H3W B C08 1 
HETATM 3399 C C09 . A1H3W D 2 .   ? 42.564 22.508 -17.654 1.00 61.63  ? 501 A1H3W B C09 1 
HETATM 3400 C C11 . A1H3W D 2 .   ? 41.641 20.854 -18.914 1.00 60.68  ? 501 A1H3W B C11 1 
HETATM 3401 C C12 . A1H3W D 2 .   ? 40.663 21.906 -18.819 1.00 59.89  ? 501 A1H3W B C12 1 
HETATM 3402 C C14 . A1H3W D 2 .   ? 39.220 20.529 -20.177 1.00 59.84  ? 501 A1H3W B C14 1 
HETATM 3403 C C16 . A1H3W D 2 .   ? 37.896 18.970 -21.449 1.00 60.67  ? 501 A1H3W B C16 1 
HETATM 3404 C C18 . A1H3W D 2 .   ? 38.197 17.604 -23.579 1.00 60.09  ? 501 A1H3W B C18 1 
HETATM 3405 C C19 . A1H3W D 2 .   ? 38.510 17.412 -24.924 1.00 60.79  ? 501 A1H3W B C19 1 
HETATM 3406 C C23 . A1H3W D 2 .   ? 40.206 19.529 -20.263 1.00 59.80  ? 501 A1H3W B C23 1 
HETATM 3407 N N05 . A1H3W D 2 .   ? 38.576 25.552 -17.798 1.00 67.21  ? 501 A1H3W B N05 1 
HETATM 3408 N N10 . A1H3W D 2 .   ? 42.785 21.232 -18.195 1.00 59.46  ? 501 A1H3W B N10 1 
HETATM 3409 O O03 . A1H3W D 2 .   ? 36.457 26.512 -18.772 1.00 68.61  ? 501 A1H3W B O03 1 
HETATM 3410 O O04 . A1H3W D 2 .   ? 38.637 27.237 -19.612 1.00 71.04  ? 501 A1H3W B O04 1 
HETATM 3411 O O15 . A1H3W D 2 .   ? 38.039 20.302 -20.830 1.00 61.92  ? 501 A1H3W B O15 1 
HETATM 3412 S S02 . A1H3W D 2 .   ? 37.832 26.821 -18.496 1.00 77.78  ? 501 A1H3W B S02 1 
HETATM 3413 O O   . HOH   E 3 .   ? 46.941 18.325 -27.839 1.00 58.40  ? 601 HOH   B O   1 
HETATM 3414 O O   . HOH   E 3 .   ? 25.610 23.843 -12.018 1.00 75.87  ? 602 HOH   B O   1 
HETATM 3415 O O   . HOH   E 3 .   ? 41.643 28.322 -14.122 1.00 67.72  ? 603 HOH   B O   1 
HETATM 3416 O O   . HOH   E 3 .   ? 49.180 14.652 -28.743 1.00 75.53  ? 604 HOH   B O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . GLY A 7   ? 1.0358 0.7121 1.1032 0.1973  0.2051  -0.0049 222 GLY A N   
2    C CA  . GLY A 7   ? 0.9672 0.7029 1.0110 0.1604  0.1774  -0.0195 222 GLY A CA  
3    C C   . GLY A 7   ? 0.9517 0.7365 1.0039 0.1706  0.1260  0.0127  222 GLY A C   
4    O O   . GLY A 7   ? 0.9425 0.7417 1.0276 0.2023  0.1071  0.0398  222 GLY A O   
5    N N   . LEU A 8   ? 0.9408 0.7547 0.9667 0.1435  0.1043  0.0075  223 LEU A N   
6    C CA  . LEU A 8   ? 0.9275 0.7867 0.9649 0.1465  0.0633  0.0290  223 LEU A CA  
7    C C   . LEU A 8   ? 0.8845 0.8036 0.9419 0.1322  0.0634  0.0232  223 LEU A C   
8    O O   . LEU A 8   ? 0.8585 0.8049 0.8933 0.1083  0.0650  0.0128  223 LEU A O   
9    C CB  . LEU A 8   ? 0.9170 0.7654 0.9184 0.1321  0.0456  0.0314  223 LEU A CB  
10   C CG  . LEU A 8   ? 0.9209 0.7884 0.9299 0.1419  0.0078  0.0515  223 LEU A CG  
11   C CD1 . LEU A 8   ? 0.9072 0.7572 0.8778 0.1301  -0.0014 0.0507  223 LEU A CD1 
12   C CD2 . LEU A 8   ? 0.8667 0.7884 0.9103 0.1345  -0.0066 0.0555  223 LEU A CD2 
13   N N   . GLY A 9   ? 0.8630 0.8086 0.9646 0.1490  0.0628  0.0335  224 GLY A N   
14   C CA  . GLY A 9   ? 0.8355 0.8356 0.9576 0.1375  0.0676  0.0342  224 GLY A CA  
15   C C   . GLY A 9   ? 0.8079 0.8303 0.9838 0.1576  0.0775  0.0413  224 GLY A C   
16   O O   . GLY A 9   ? 0.8205 0.8187 1.0177 0.1829  0.0823  0.0445  224 GLY A O   
17   N N   . THR A 10  ? 0.7917 0.8639 0.9921 0.1484  0.0831  0.0476  225 THR A N   
18   C CA  . THR A 10  ? 0.7603 0.8662 1.0183 0.1631  0.0972  0.0537  225 THR A CA  
19   C C   . THR A 10  ? 0.7423 0.8704 0.9860 0.1540  0.1377  0.0371  225 THR A C   
20   O O   . THR A 10  ? 0.7520 0.8694 0.9399 0.1368  0.1524  0.0166  225 THR A O   
21   C CB  . THR A 10  ? 0.7175 0.8649 1.0251 0.1578  0.0731  0.0756  225 THR A CB  
22   O OG1 . THR A 10  ? 0.7296 0.8948 1.0139 0.1349  0.0772  0.0839  225 THR A OG1 
23   C CG2 . THR A 10  ? 0.7016 0.8294 1.0129 0.1633  0.0330  0.0823  225 THR A CG2 
24   N N   . ALA A 11  ? 0.7123 0.8784 1.0076 0.1645  0.1568  0.0428  226 ALA A N   
25   C CA  . ALA A 11  ? 0.7309 0.9280 1.0084 0.1543  0.1966  0.0283  226 ALA A CA  
26   C C   . ALA A 11  ? 0.7398 0.9754 0.9818 0.1297  0.1919  0.0431  226 ALA A C   
27   O O   . ALA A 11  ? 0.7512 1.0175 0.9546 0.1182  0.2205  0.0305  226 ALA A O   
28   C CB  . ALA A 11  ? 0.6697 0.9057 1.0152 0.1714  0.2217  0.0348  226 ALA A CB  
29   N N   . ARG A 12  ? 0.7003 0.9368 0.9541 0.1234  0.1588  0.0700  227 ARG A N   
30   C CA  . ARG A 12  ? 0.7444 1.0148 0.9805 0.1082  0.1577  0.0962  227 ARG A CA  
31   C C   . ARG A 12  ? 0.7886 1.0464 0.9653 0.0977  0.1384  0.0959  227 ARG A C   
32   O O   . ARG A 12  ? 0.7061 1.0020 0.8498 0.0894  0.1451  0.1134  227 ARG A O   
33   C CB  . ARG A 12  ? 0.7237 1.0019 1.0251 0.1073  0.1431  0.1269  227 ARG A CB  
34   C CG  . ARG A 12  ? 0.7090 1.0177 1.0828 0.1137  0.1621  0.1305  227 ARG A CG  
35   C CD  . ARG A 12  ? 0.6926 1.0221 1.1242 0.1009  0.1624  0.1613  227 ARG A CD  
36   N NE  . ARG A 12  ? 0.7078 1.0410 1.0976 0.0906  0.1727  0.1895  227 ARG A NE  
37   C CZ  . ARG A 12  ? 0.7112 1.0582 1.1388 0.0804  0.1894  0.2238  227 ARG A CZ  
38   N NH1 . ARG A 12  ? 0.7074 1.0692 1.2183 0.0720  0.1987  0.2282  227 ARG A NH1 
39   N NH2 . ARG A 12  ? 0.7416 1.0916 1.1260 0.0789  0.1999  0.2564  227 ARG A NH2 
40   N N   . LEU A 13  ? 0.7874 0.9987 0.9525 0.1002  0.1150  0.0808  228 LEU A N   
41   C CA  . LEU A 13  ? 0.7893 0.9916 0.9083 0.0905  0.0971  0.0804  228 LEU A CA  
42   C C   . LEU A 13  ? 0.7978 0.9482 0.8980 0.0925  0.0888  0.0527  228 LEU A C   
43   O O   . LEU A 13  ? 0.7654 0.8807 0.8969 0.1069  0.0796  0.0525  228 LEU A O   
44   C CB  . LEU A 13  ? 0.7839 0.9823 0.9261 0.0916  0.0747  0.1124  228 LEU A CB  
45   C CG  . LEU A 13  ? 0.7936 0.9925 0.8977 0.0864  0.0596  0.1193  228 LEU A CG  
46   C CD1 . LEU A 13  ? 0.7687 1.0294 0.8369 0.0812  0.0737  0.1335  228 LEU A CD1 
47   C CD2 . LEU A 13  ? 0.7601 0.9322 0.8972 0.0909  0.0409  0.1419  228 LEU A CD2 
48   N N   . GLN A 14  ? 0.8079 0.9589 0.8589 0.0780  0.0936  0.0309  229 GLN A N   
49   C CA  . GLN A 14  ? 0.8164 0.9140 0.8485 0.0757  0.0964  0.0038  229 GLN A CA  
50   C C   . GLN A 14  ? 0.8393 0.9420 0.8373 0.0602  0.0809  0.0009  229 GLN A C   
51   O O   . GLN A 14  ? 0.8137 0.9736 0.7891 0.0467  0.0800  0.0025  229 GLN A O   
52   C CB  . GLN A 14  ? 0.8143 0.9039 0.8291 0.0670  0.1321  -0.0345 229 GLN A CB  
53   C CG  . GLN A 14  ? 0.8234 0.9157 0.8748 0.0845  0.1546  -0.0338 229 GLN A CG  
54   C CD  . GLN A 14  ? 0.8577 1.0127 0.8909 0.0714  0.1789  -0.0457 229 GLN A CD  
55   O OE1 . GLN A 14  ? 0.8689 1.0589 0.8541 0.0476  0.1841  -0.0676 229 GLN A OE1 
56   N NE2 . GLN A 14  ? 0.7893 0.9666 0.8604 0.0864  0.1943  -0.0322 229 GLN A NE2 
57   N N   . LEU A 15  ? 0.8543 0.9051 0.8500 0.0649  0.0686  0.0008  230 LEU A N   
58   C CA  . LEU A 15  ? 0.8822 0.9353 0.8505 0.0505  0.0585  -0.0044 230 LEU A CA  
59   C C   . LEU A 15  ? 0.8870 0.9396 0.8261 0.0253  0.0830  -0.0445 230 LEU A C   
60   O O   . LEU A 15  ? 0.9088 0.9136 0.8487 0.0252  0.1078  -0.0668 230 LEU A O   
61   C CB  . LEU A 15  ? 0.8893 0.8875 0.8602 0.0628  0.0425  0.0072  230 LEU A CB  
62   C CG  . LEU A 15  ? 0.9070 0.9046 0.8527 0.0481  0.0380  0.0004  230 LEU A CG  
63   C CD1 . LEU A 15  ? 0.8744 0.9281 0.8251 0.0473  0.0209  0.0197  230 LEU A CD1 
64   C CD2 . LEU A 15  ? 0.9199 0.8562 0.8564 0.0586  0.0322  0.0062  230 LEU A CD2 
65   N N   . VAL A 16  ? 0.8564 0.9653 0.7743 0.0039  0.0786  -0.0551 231 VAL A N   
66   C CA  . VAL A 16  ? 0.9481 1.0717 0.8418 -0.0288 0.1006  -0.1015 231 VAL A CA  
67   C C   . VAL A 16  ? 0.9543 1.0559 0.8413 -0.0450 0.0987  -0.1126 231 VAL A C   
68   O O   . VAL A 16  ? 0.9711 1.0194 0.8522 -0.0638 0.1248  -0.1451 231 VAL A O   
69   C CB  . VAL A 16  ? 0.9179 1.1450 0.7921 -0.0454 0.0979  -0.1117 231 VAL A CB  
70   C CG1 . VAL A 16  ? 0.9030 1.1614 0.7527 -0.0866 0.1168  -0.1686 231 VAL A CG1 
71   C CG2 . VAL A 16  ? 0.8958 1.1364 0.7742 -0.0308 0.1086  -0.1023 231 VAL A CG2 
72   N N   . GLU A 17  ? 0.9209 1.0580 0.8124 -0.0369 0.0729  -0.0843 232 GLU A N   
73   C CA  . GLU A 17  ? 0.8999 1.0279 0.7885 -0.0513 0.0724  -0.0925 232 GLU A CA  
74   C C   . GLU A 17  ? 0.9147 1.0404 0.8155 -0.0246 0.0474  -0.0509 232 GLU A C   
75   O O   . GLU A 17  ? 0.8428 1.0105 0.7550 -0.0058 0.0298  -0.0215 232 GLU A O   
76   C CB  . GLU A 17  ? 0.8597 1.0756 0.7402 -0.0863 0.0749  -0.1243 232 GLU A CB  
77   C CG  . GLU A 17  ? 0.9270 1.1080 0.8084 -0.1144 0.0934  -0.1532 232 GLU A CG  
78   C CD  . GLU A 17  ? 0.9118 1.1819 0.7926 -0.1579 0.0991  -0.1964 232 GLU A CD  
79   O OE1 . GLU A 17  ? 0.9058 1.2606 0.7761 -0.1683 0.0914  -0.2117 232 GLU A OE1 
80   O OE2 . GLU A 17  ? 0.9154 1.1779 0.8063 -0.1827 0.1113  -0.2154 232 GLU A OE2 
81   N N   . PHE A 18  ? 0.8594 0.9303 0.7571 -0.0230 0.0508  -0.0490 233 PHE A N   
82   C CA  . PHE A 18  ? 0.9232 0.9883 0.8282 -0.0018 0.0325  -0.0195 233 PHE A CA  
83   C C   . PHE A 18  ? 0.9098 0.9588 0.8066 -0.0161 0.0439  -0.0307 233 PHE A C   
84   O O   . PHE A 18  ? 0.8494 0.8345 0.7314 -0.0255 0.0640  -0.0440 233 PHE A O   
85   C CB  . PHE A 18  ? 0.8932 0.8953 0.8003 0.0258  0.0221  0.0022  233 PHE A CB  
86   C CG  . PHE A 18  ? 0.9049 0.8957 0.8146 0.0419  0.0080  0.0212  233 PHE A CG  
87   C CD1 . PHE A 18  ? 0.9204 0.8679 0.8098 0.0412  0.0151  0.0173  233 PHE A CD1 
88   C CD2 . PHE A 18  ? 0.8791 0.9023 0.8114 0.0570  -0.0069 0.0425  233 PHE A CD2 
89   C CE1 . PHE A 18  ? 0.8974 0.8370 0.7855 0.0549  0.0057  0.0289  233 PHE A CE1 
90   C CE2 . PHE A 18  ? 0.8731 0.8804 0.8104 0.0704  -0.0139 0.0535  233 PHE A CE2 
91   C CZ  . PHE A 18  ? 0.8855 0.8531 0.7986 0.0689  -0.0083 0.0437  233 PHE A CZ  
92   N N   . SER A 19  ? 0.8589 0.9647 0.7684 -0.0152 0.0347  -0.0216 234 SER A N   
93   C CA  . SER A 19  ? 0.9107 1.0085 0.8180 -0.0279 0.0477  -0.0306 234 SER A CA  
94   C C   . SER A 19  ? 0.8788 0.9970 0.7997 -0.0036 0.0351  -0.0052 234 SER A C   
95   O O   . SER A 19  ? 0.8357 0.9945 0.7752 0.0170  0.0186  0.0169  234 SER A O   
96   C CB  . SER A 19  ? 0.8723 1.0371 0.7900 -0.0663 0.0614  -0.0632 234 SER A CB  
97   O OG  . SER A 19  ? 0.8508 1.1241 0.7908 -0.0636 0.0433  -0.0550 234 SER A OG  
98   N N   . ALA A 20  ? 0.9085 0.9909 0.8197 -0.0046 0.0481  -0.0071 235 ALA A N   
99   C CA  . ALA A 20  ? 0.8929 1.0029 0.8206 0.0130  0.0452  0.0079  235 ALA A CA  
100  C C   . ALA A 20  ? 0.8472 0.9890 0.7834 -0.0114 0.0666  -0.0092 235 ALA A C   
101  O O   . ALA A 20  ? 0.8407 0.9358 0.7564 -0.0347 0.0877  -0.0265 235 ALA A O   
102  C CB  . ALA A 20  ? 0.8668 0.9044 0.7736 0.0386  0.0410  0.0209  235 ALA A CB  
103  N N   . PHE A 21  ? 0.8402 1.0645 0.8122 -0.0061 0.0644  -0.0026 236 PHE A N   
104  C CA  . PHE A 21  ? 0.8747 1.1627 0.8699 -0.0372 0.0817  -0.0237 236 PHE A CA  
105  C C   . PHE A 21  ? 0.8524 1.2089 0.8865 -0.0170 0.0835  -0.0080 236 PHE A C   
106  O O   . PHE A 21  ? 0.8348 1.1929 0.8806 0.0216  0.0718  0.0195  236 PHE A O   
107  C CB  . PHE A 21  ? 0.8561 1.2251 0.8671 -0.0683 0.0737  -0.0463 236 PHE A CB  
108  C CG  . PHE A 21  ? 0.8276 1.2802 0.8575 -0.0444 0.0452  -0.0235 236 PHE A CG  
109  C CD1 . PHE A 21  ? 0.8408 1.2494 0.8496 -0.0232 0.0307  -0.0058 236 PHE A CD1 
110  C CD2 . PHE A 21  ? 0.8264 1.4076 0.8972 -0.0421 0.0348  -0.0164 236 PHE A CD2 
111  C CE1 . PHE A 21  ? 0.8125 1.2938 0.8365 -0.0007 0.0103  0.0210  236 PHE A CE1 
112  C CE2 . PHE A 21  ? 0.8108 1.4716 0.8949 -0.0151 0.0108  0.0136  236 PHE A CE2 
113  C CZ  . PHE A 21  ? 0.7970 1.4028 0.8555 0.0052  0.0007  0.0335  236 PHE A CZ  
114  N N   . VAL A 22  ? 0.8435 1.2559 0.9037 -0.0441 0.1025  -0.0267 237 VAL A N   
115  C CA  . VAL A 22  ? 0.8688 1.3765 0.9805 -0.0281 0.1050  -0.0144 237 VAL A CA  
116  C C   . VAL A 22  ? 0.8596 1.4876 1.0128 -0.0694 0.1061  -0.0413 237 VAL A C   
117  O O   . VAL A 22  ? 0.8589 1.4618 1.0003 -0.1167 0.1251  -0.0762 237 VAL A O   
118  C CB  . VAL A 22  ? 0.8797 1.3320 0.9856 -0.0148 0.1336  -0.0103 237 VAL A CB  
119  C CG1 . VAL A 22  ? 0.8819 1.2679 0.9564 -0.0544 0.1646  -0.0355 237 VAL A CG1 
120  C CG2 . VAL A 22  ? 0.8744 1.4334 1.0431 0.0018  0.1409  0.0004  237 VAL A CG2 
121  N N   . GLU A 23  ? 1.0754 1.6131 0.7717 0.0850  -0.1062 -0.0773 238 GLU A N   
122  C CA  . GLU A 23  ? 1.1201 1.7087 0.8233 0.0667  -0.1266 -0.1277 238 GLU A CA  
123  C C   . GLU A 23  ? 1.1545 1.8030 0.9296 0.0418  -0.1405 -0.1416 238 GLU A C   
124  O O   . GLU A 23  ? 1.1430 1.7790 0.9739 0.0066  -0.1336 -0.1672 238 GLU A O   
125  C CB  . GLU A 23  ? 1.1453 1.7742 0.7768 0.0953  -0.1499 -0.1362 238 GLU A CB  
126  C CG  . GLU A 23  ? 1.1324 1.7093 0.6915 0.1235  -0.1371 -0.1185 238 GLU A CG  
127  C CD  . GLU A 23  ? 1.1615 1.7313 0.6738 0.1225  -0.1415 -0.1584 238 GLU A CD  
128  O OE1 . GLU A 23  ? 1.1906 1.7484 0.7303 0.0926  -0.1386 -0.1982 238 GLU A OE1 
129  O OE2 . GLU A 23  ? 1.1848 1.7295 0.6591 0.1455  -0.1400 -0.1420 238 GLU A OE2 
130  N N   . PRO A 24  ? 1.3120 2.0267 1.0924 0.0580  -0.1598 -0.1252 239 PRO A N   
131  C CA  . PRO A 24  ? 1.2954 2.0383 1.0198 0.0984  -0.1722 -0.0948 239 PRO A CA  
132  C C   . PRO A 24  ? 1.3149 2.1197 1.0008 0.1072  -0.2039 -0.1246 239 PRO A C   
133  O O   . PRO A 24  ? 1.3484 2.1420 1.0173 0.0920  -0.2097 -0.1634 239 PRO A O   
134  C CB  . PRO A 24  ? 1.3050 2.0813 1.0797 0.1015  -0.1704 -0.0638 239 PRO A CB  
135  C CG  . PRO A 24  ? 1.2320 2.0477 1.0892 0.0613  -0.1764 -0.0959 239 PRO A CG  
136  C CD  . PRO A 24  ? 1.2688 2.0418 1.1261 0.0327  -0.1713 -0.1371 239 PRO A CD  
137  N N   . PRO A 25  ? 1.2769 2.1079 0.9666 0.1260  -0.2119 -0.1050 240 PRO A N   
138  C CA  . PRO A 25  ? 1.2853 2.1355 0.9566 0.1258  -0.2304 -0.1315 240 PRO A CA  
139  C C   . PRO A 25  ? 1.2490 2.1804 0.9660 0.0978  -0.2614 -0.1696 240 PRO A C   
140  O O   . PRO A 25  ? 1.2336 2.1701 0.9339 0.0834  -0.2792 -0.2086 240 PRO A O   
141  C CB  . PRO A 25  ? 1.2907 2.1245 0.9535 0.1532  -0.2226 -0.0955 240 PRO A CB  
142  C CG  . PRO A 25  ? 1.2622 2.0765 0.9475 0.1645  -0.2026 -0.0547 240 PRO A CG  
143  C CD  . PRO A 25  ? 1.2460 2.0831 0.9592 0.1444  -0.2030 -0.0635 240 PRO A CD  
144  N N   . ARG A 33  ? 0.9783 1.5009 0.7898 -0.0471 -0.1124 -0.2643 248 ARG A N   
145  C CA  . ARG A 33  ? 0.9439 1.4032 0.7360 -0.0281 -0.0824 -0.2232 248 ARG A CA  
146  C C   . ARG A 33  ? 0.9167 1.3289 0.7764 -0.0543 -0.0573 -0.2099 248 ARG A C   
147  O O   . ARG A 33  ? 0.9258 1.3242 0.8292 -0.0877 -0.0532 -0.2424 248 ARG A O   
148  C CB  . ARG A 33  ? 0.9831 1.3908 0.7095 -0.0123 -0.0688 -0.2328 248 ARG A CB  
149  C CG  . ARG A 33  ? 1.0413 1.4554 0.6936 0.0303  -0.0731 -0.2041 248 ARG A CG  
150  C CD  . ARG A 33  ? 1.0011 1.3461 0.6070 0.0465  -0.0469 -0.1933 248 ARG A CD  
151  N NE  . ARG A 33  ? 1.0704 1.4333 0.5982 0.0819  -0.0576 -0.1874 248 ARG A NE  
152  C CZ  . ARG A 33  ? 1.0970 1.4215 0.5713 0.0977  -0.0430 -0.1936 248 ARG A CZ  
153  N NH1 . ARG A 33  ? 1.1183 1.3802 0.6075 0.0839  -0.0146 -0.2017 248 ARG A NH1 
154  N NH2 . ARG A 33  ? 1.1226 1.4725 0.5267 0.1289  -0.0563 -0.1916 248 ARG A NH2 
155  N N   . HIS A 34  ? 0.9265 1.3125 0.7928 -0.0391 -0.0423 -0.1618 249 HIS A N   
156  C CA  . HIS A 34  ? 0.9083 1.2311 0.8208 -0.0568 -0.0151 -0.1416 249 HIS A CA  
157  C C   . HIS A 34  ? 0.9058 1.1600 0.7722 -0.0332 0.0050  -0.1079 249 HIS A C   
158  O O   . HIS A 34  ? 0.9349 1.1932 0.7557 -0.0005 -0.0010 -0.0729 249 HIS A O   
159  C CB  . HIS A 34  ? 0.8899 1.2320 0.8520 -0.0607 -0.0148 -0.1112 249 HIS A CB  
160  C CG  . HIS A 34  ? 0.8703 1.1407 0.8664 -0.0720 0.0120  -0.0821 249 HIS A CG  
161  N ND1 . HIS A 34  ? 0.8648 1.1110 0.9260 -0.1092 0.0256  -0.1010 249 HIS A ND1 
162  C CD2 . HIS A 34  ? 0.8770 1.0920 0.8500 -0.0516 0.0256  -0.0352 249 HIS A CD2 
163  C CE1 . HIS A 34  ? 0.8667 1.0467 0.9433 -0.1109 0.0474  -0.0672 249 HIS A CE1 
164  N NE2 . HIS A 34  ? 0.8846 1.0430 0.9079 -0.0766 0.0469  -0.0269 249 HIS A NE2 
165  N N   . LEU A 35  ? 0.8899 1.0808 0.7703 -0.0497 0.0281  -0.1164 250 LEU A N   
166  C CA  . LEU A 35  ? 0.9168 1.0395 0.7651 -0.0310 0.0488  -0.0824 250 LEU A CA  
167  C C   . LEU A 35  ? 0.9111 0.9796 0.8011 -0.0398 0.0655  -0.0425 250 LEU A C   
168  O O   . LEU A 35  ? 0.8915 0.9411 0.8409 -0.0715 0.0765  -0.0560 250 LEU A O   
169  C CB  . LEU A 35  ? 0.9114 0.9934 0.7482 -0.0404 0.0662  -0.1111 250 LEU A CB  
170  C CG  . LEU A 35  ? 0.8992 1.0229 0.6924 -0.0355 0.0511  -0.1573 250 LEU A CG  
171  C CD1 . LEU A 35  ? 0.9266 1.0199 0.7364 -0.0623 0.0642  -0.2032 250 LEU A CD1 
172  C CD2 . LEU A 35  ? 0.8983 1.0210 0.6165 0.0037  0.0495  -0.1371 250 LEU A CD2 
173  N N   . PHE A 36  ? 0.8956 0.9354 0.7525 -0.0119 0.0661  0.0067  251 PHE A N   
174  C CA  . PHE A 36  ? 0.9227 0.8973 0.8101 -0.0187 0.0810  0.0468  251 PHE A CA  
175  C C   . PHE A 36  ? 0.9295 0.8306 0.8253 -0.0272 0.1049  0.0547  251 PHE A C   
176  O O   . PHE A 36  ? 0.9023 0.7528 0.8464 -0.0506 0.1211  0.0631  251 PHE A O   
177  C CB  . PHE A 36  ? 0.9261 0.8899 0.7731 0.0137  0.0697  0.0982  251 PHE A CB  
178  C CG  . PHE A 36  ? 0.9504 0.9884 0.7760 0.0310  0.0463  0.0948  251 PHE A CG  
179  C CD1 . PHE A 36  ? 0.9027 0.9742 0.7718 0.0160  0.0421  0.0881  251 PHE A CD1 
180  C CD2 . PHE A 36  ? 0.9411 1.0160 0.7045 0.0630  0.0293  0.0998  251 PHE A CD2 
181  C CE1 . PHE A 36  ? 0.9201 1.0618 0.7735 0.0328  0.0220  0.0868  251 PHE A CE1 
182  C CE2 . PHE A 36  ? 0.9392 1.0827 0.6844 0.0791  0.0078  0.0971  251 PHE A CE2 
183  C CZ  . PHE A 36  ? 0.9567 1.1345 0.7481 0.0642  0.0043  0.0909  251 PHE A CZ  
184  N N   . VAL A 37  ? 0.9217 0.8156 0.7721 -0.0078 0.1086  0.0536  252 VAL A N   
185  C CA  . VAL A 37  ? 0.9245 0.7550 0.7853 -0.0149 0.1336  0.0581  252 VAL A CA  
186  C C   . VAL A 37  ? 0.9234 0.7783 0.7418 -0.0027 0.1362  0.0255  252 VAL A C   
187  O O   . VAL A 37  ? 0.9261 0.8308 0.6931 0.0215  0.1180  0.0201  252 VAL A O   
188  C CB  . VAL A 37  ? 0.9149 0.6818 0.7627 0.0039  0.1401  0.1185  252 VAL A CB  
189  C CG1 . VAL A 37  ? 0.9399 0.6718 0.8276 -0.0105 0.1381  0.1483  252 VAL A CG1 
190  C CG2 . VAL A 37  ? 0.9470 0.7403 0.7289 0.0424  0.1230  0.1435  252 VAL A CG2 
191  N N   . HIS A 38  ? 0.9243 0.7404 0.7613 -0.0181 0.1596  0.0049  253 HIS A N   
192  C CA  . HIS A 38  ? 0.9280 0.7618 0.7249 -0.0094 0.1643  -0.0329 253 HIS A CA  
193  C C   . HIS A 38  ? 0.9820 0.7506 0.7872 -0.0111 0.1967  -0.0268 253 HIS A C   
194  O O   . HIS A 38  ? 0.9708 0.6970 0.8306 -0.0385 0.2141  -0.0313 253 HIS A O   
195  C CB  . HIS A 38  ? 0.9117 0.7924 0.7238 -0.0344 0.1512  -0.0924 253 HIS A CB  
196  C CG  . HIS A 38  ? 0.9665 0.8630 0.7290 -0.0251 0.1515  -0.1342 253 HIS A CG  
197  N ND1 . HIS A 38  ? 1.0120 0.9338 0.7048 0.0095  0.1426  -0.1277 253 HIS A ND1 
198  C CD2 . HIS A 38  ? 1.0178 0.9049 0.7857 -0.0451 0.1587  -0.1835 253 HIS A CD2 
199  C CE1 . HIS A 38  ? 1.0557 0.9814 0.7112 0.0111  0.1453  -0.1711 253 HIS A CE1 
200  N NE2 . HIS A 38  ? 1.0724 0.9759 0.7708 -0.0215 0.1544  -0.2058 253 HIS A NE2 
201  N N   . ILE A 39  ? 1.0167 0.7791 0.7684 0.0186  0.2057  -0.0174 254 ILE A N   
202  C CA  . ILE A 39  ? 1.0470 0.7553 0.7986 0.0223  0.2385  -0.0151 254 ILE A CA  
203  C C   . ILE A 39  ? 1.0907 0.8251 0.7834 0.0369  0.2402  -0.0592 254 ILE A C   
204  O O   . ILE A 39  ? 1.1073 0.8683 0.7403 0.0688  0.2317  -0.0486 254 ILE A O   
205  C CB  . ILE A 39  ? 1.0689 0.7359 0.8121 0.0480  0.2521  0.0474  254 ILE A CB  
206  C CG1 . ILE A 39  ? 1.0307 0.6589 0.8279 0.0339  0.2497  0.0938  254 ILE A CG1 
207  C CG2 . ILE A 39  ? 1.0707 0.6921 0.8077 0.0571  0.2872  0.0478  254 ILE A CG2 
208  C CD1 . ILE A 39  ? 1.0158 0.6124 0.7966 0.0618  0.2514  0.1587  254 ILE A CD1 
209  N N   . SER A 40  ? 1.0985 0.8204 0.8041 0.0148  0.2510  -0.1077 255 SER A N   
210  C CA  . SER A 40  ? 1.1636 0.8917 0.8099 0.0288  0.2570  -0.1490 255 SER A CA  
211  C C   . SER A 40  ? 1.1948 0.8573 0.8435 0.0357  0.2980  -0.1401 255 SER A C   
212  O O   . SER A 40  ? 1.1853 0.8019 0.8945 0.0134  0.3179  -0.1293 255 SER A O   
213  C CB  . SER A 40  ? 1.2007 0.9592 0.8499 0.0015  0.2371  -0.2125 255 SER A CB  
214  O OG  . SER A 40  ? 1.2988 1.0728 0.8739 0.0202  0.2318  -0.2507 255 SER A OG  
215  N N   . GLN A 41  ? 1.2017 0.7570 0.8985 0.0725  0.2068  -0.1910 256 GLN A N   
216  C CA  . GLN A 41  ? 1.2495 0.7444 0.9677 0.0717  0.2327  -0.1565 256 GLN A CA  
217  C C   . GLN A 41  ? 1.2350 0.7195 0.9570 0.0645  0.2386  -0.1589 256 GLN A C   
218  O O   . GLN A 41  ? 1.2149 0.7316 0.9280 0.0742  0.2117  -0.1770 256 GLN A O   
219  C CB  . GLN A 41  ? 1.2179 0.7107 0.9544 0.0921  0.2177  -0.1343 256 GLN A CB  
220  C CG  . GLN A 41  ? 1.1872 0.6713 0.9220 0.0993  0.2222  -0.1228 256 GLN A CG  
221  C CD  . GLN A 41  ? 1.1626 0.6478 0.9216 0.1170  0.2099  -0.1023 256 GLN A CD  
222  O OE1 . GLN A 41  ? 1.1668 0.6276 0.9491 0.1253  0.2225  -0.0755 256 GLN A OE1 
223  N NE2 . GLN A 41  ? 1.1655 0.6811 0.9218 0.1229  0.1852  -0.1145 256 GLN A NE2 
224  N N   . PRO A 49  ? 1.6951 0.9797 1.7805 0.2322  0.3281  0.2577  264 PRO A N   
225  C CA  . PRO A 49  ? 1.6854 0.9944 1.7520 0.2403  0.2967  0.2775  264 PRO A CA  
226  C C   . PRO A 49  ? 1.6208 0.9894 1.7254 0.2489  0.2700  0.2612  264 PRO A C   
227  O O   . PRO A 49  ? 1.5943 0.9865 1.6812 0.2546  0.2459  0.2760  264 PRO A O   
228  C CB  . PRO A 49  ? 1.6798 0.9534 1.6740 0.2043  0.3144  0.2577  264 PRO A CB  
229  C CG  . PRO A 49  ? 1.6916 0.9410 1.6791 0.1778  0.3505  0.2167  264 PRO A CG  
230  C CD  . PRO A 49  ? 1.6755 0.9436 1.7228 0.1944  0.3534  0.2136  264 PRO A CD  
231  N N   . PRO A 50  ? 1.6424 1.0328 1.7930 0.2483  0.2767  0.2324  265 PRO A N   
232  C CA  . PRO A 50  ? 1.5985 1.0352 1.7772 0.2504  0.2594  0.2097  265 PRO A CA  
233  C C   . PRO A 50  ? 1.5219 0.9971 1.7012 0.2660  0.2286  0.2275  265 PRO A C   
234  O O   . PRO A 50  ? 1.4690 0.9953 1.7059 0.2875  0.2113  0.2324  265 PRO A O   
235  C CB  . PRO A 50  ? 1.5920 1.0532 1.8436 0.2714  0.2620  0.2137  265 PRO A CB  
236  C CG  . PRO A 50  ? 1.5806 0.9971 1.8239 0.2621  0.2925  0.2125  265 PRO A CG  
237  C CD  . PRO A 50  ? 1.6333 1.0051 1.8102 0.2451  0.3030  0.2207  265 PRO A CD  
238  N N   . LEU A 51  ? 1.4761 0.9356 1.5933 0.2529  0.2227  0.2341  266 LEU A N   
239  C CA  . LEU A 51  ? 1.3640 0.9033 1.4586 0.2376  0.1822  0.2194  266 LEU A CA  
240  C C   . LEU A 51  ? 1.3093 0.9243 1.4389 0.2580  0.1423  0.2534  266 LEU A C   
241  O O   . LEU A 51  ? 1.2783 0.9340 1.4759 0.2791  0.1342  0.2549  266 LEU A O   
242  C CB  . LEU A 51  ? 1.2899 0.8473 1.3936 0.2265  0.1845  0.1722  266 LEU A CB  
243  C CG  . LEU A 51  ? 1.2210 0.7742 1.2571 0.1977  0.1830  0.1330  266 LEU A CG  
244  C CD1 . LEU A 51  ? 1.2488 0.7314 1.2447 0.1852  0.2148  0.1254  266 LEU A CD1 
245  C CD2 . LEU A 51  ? 1.1776 0.7349 1.2185 0.1947  0.1871  0.0928  266 LEU A CD2 
246  N N   . GLU A 52  ? 1.2287 0.8681 1.3107 0.2491  0.1171  0.2767  267 GLU A N   
247  C CA  . GLU A 52  ? 1.1645 0.8840 1.2664 0.2641  0.0738  0.3055  267 GLU A CA  
248  C C   . GLU A 52  ? 1.0768 0.8783 1.2106 0.2532  0.0512  0.2696  267 GLU A C   
249  O O   . GLU A 52  ? 1.0859 0.8753 1.2071 0.2320  0.0668  0.2253  267 GLU A O   
250  C CB  . GLU A 52  ? 1.1934 0.9200 1.2208 0.2455  0.0538  0.3264  267 GLU A CB  
251  C CG  . GLU A 52  ? 1.2461 0.8954 1.2384 0.2591  0.0726  0.3712  267 GLU A CG  
252  C CD  . GLU A 52  ? 1.3666 1.0309 1.2889 0.2455  0.0479  0.3993  267 GLU A CD  
253  O OE1 . GLU A 52  ? 1.4414 1.1859 1.3741 0.2546  0.0046  0.4151  267 GLU A OE1 
254  O OE2 . GLU A 52  ? 1.4634 1.0601 1.3180 0.2226  0.0736  0.4032  267 GLU A OE2 
255  N N   . SER A 53  ? 1.0564 0.9411 1.2264 0.2676  0.0143  0.2884  268 SER A N   
256  C CA  . SER A 53  ? 0.9955 0.9629 1.1921 0.2520  -0.0060 0.2539  268 SER A CA  
257  C C   . SER A 53  ? 0.9718 1.0143 1.1299 0.2360  -0.0481 0.2649  268 SER A C   
258  O O   . SER A 53  ? 0.9728 1.0214 1.1062 0.2494  -0.0696 0.3090  268 SER A O   
259  C CB  . SER A 53  ? 0.9469 0.9622 1.2386 0.2782  -0.0074 0.2519  268 SER A CB  
260  O OG  . SER A 53  ? 0.9383 1.0229 1.2652 0.3066  -0.0445 0.2926  268 SER A OG  
261  N N   . VAL A 54  ? 0.9533 1.0454 1.0999 0.2064  -0.0569 0.2241  269 VAL A N   
262  C CA  . VAL A 54  ? 0.9577 1.1260 1.0703 0.1844  -0.0928 0.2239  269 VAL A CA  
263  C C   . VAL A 54  ? 0.9458 1.1985 1.1105 0.1749  -0.1053 0.1921  269 VAL A C   
264  O O   . VAL A 54  ? 0.9461 1.1774 1.1318 0.1654  -0.0781 0.1514  269 VAL A O   
265  C CB  . VAL A 54  ? 0.9839 1.1221 1.0165 0.1492  -0.0846 0.1983  269 VAL A CB  
266  C CG1 . VAL A 54  ? 0.9973 1.2167 1.0041 0.1212  -0.1144 0.1837  269 VAL A CG1 
267  C CG2 . VAL A 54  ? 0.9755 1.0487 0.9526 0.1504  -0.0758 0.2290  269 VAL A CG2 
268  N N   . ASP A 55  ? 0.9388 1.2855 1.1196 0.1754  -0.1446 0.2083  270 ASP A N   
269  C CA  . ASP A 55  ? 0.9305 1.3657 1.1613 0.1599  -0.1544 0.1724  270 ASP A CA  
270  C C   . ASP A 55  ? 0.9798 1.4193 1.1542 0.1152  -0.1467 0.1280  270 ASP A C   
271  O O   . ASP A 55  ? 1.0132 1.4717 1.1268 0.0951  -0.1670 0.1361  270 ASP A O   
272  C CB  . ASP A 55  ? 0.9184 1.4640 1.1875 0.1745  -0.2010 0.1998  270 ASP A CB  
273  C CG  . ASP A 55  ? 0.9107 1.5567 1.2448 0.1568  -0.2072 0.1569  270 ASP A CG  
274  O OD1 . ASP A 55  ? 0.9185 1.5970 1.2182 0.1147  -0.2067 0.1191  270 ASP A OD1 
275  O OD2 . ASP A 55  ? 0.8913 1.5833 1.3123 0.1831  -0.2089 0.1576  270 ASP A OD2 
276  N N   . VAL A 56  ? 1.0171 1.4337 1.2087 0.1002  -0.1148 0.0809  271 VAL A N   
277  C CA  . VAL A 56  ? 1.0700 1.4696 1.2051 0.0645  -0.0998 0.0374  271 VAL A CA  
278  C C   . VAL A 56  ? 1.0898 1.5830 1.2063 0.0342  -0.1302 0.0284  271 VAL A C   
279  O O   . VAL A 56  ? 1.1327 1.6140 1.1851 0.0078  -0.1286 0.0100  271 VAL A O   
280  C CB  . VAL A 56  ? 1.0419 1.4013 1.2005 0.0573  -0.0602 -0.0080 271 VAL A CB  
281  C CG1 . VAL A 56  ? 1.0192 1.4678 1.2467 0.0462  -0.0657 -0.0283 271 VAL A CG1 
282  C CG2 . VAL A 56  ? 1.0651 1.3707 1.1527 0.0327  -0.0378 -0.0472 271 VAL A CG2 
283  N N   . ARG A 57  ? 0.9867 1.5781 1.1593 0.0377  -0.1587 0.0392  272 ARG A N   
284  C CA  . ARG A 57  ? 0.9712 1.6586 1.1255 0.0061  -0.1887 0.0285  272 ARG A CA  
285  C C   . ARG A 57  ? 1.0058 1.6851 1.0835 -0.0023 -0.2125 0.0579  272 ARG A C   
286  O O   . ARG A 57  ? 1.0189 1.7491 1.0566 -0.0378 -0.2259 0.0396  272 ARG A O   
287  C CB  . ARG A 57  ? 0.9254 1.7282 1.1550 0.0187  -0.2224 0.0411  272 ARG A CB  
288  C CG  . ARG A 57  ? 0.8925 1.7048 1.2114 0.0349  -0.1992 0.0195  272 ARG A CG  
289  C CD  . ARG A 57  ? 0.8514 1.8019 1.2410 0.0229  -0.2237 -0.0018 272 ARG A CD  
290  N NE  . ARG A 57  ? 0.8129 1.7963 1.3011 0.0581  -0.2214 0.0038  272 ARG A NE  
291  C CZ  . ARG A 57  ? 0.8496 1.8257 1.3692 0.1100  -0.2433 0.0568  272 ARG A CZ  
292  N NH1 . ARG A 57  ? 0.8735 1.7995 1.3282 0.1310  -0.2652 0.1094  272 ARG A NH1 
293  N NH2 . ARG A 57  ? 0.8146 1.8314 1.4323 0.1409  -0.2395 0.0551  272 ARG A NH2 
294  N N   . GLN A 58  ? 1.0512 1.6635 1.1048 0.0256  -0.2133 0.0999  273 GLN A N   
295  C CA  . GLN A 58  ? 1.0736 1.6718 1.0516 0.0143  -0.2303 0.1264  273 GLN A CA  
296  C C   . GLN A 58  ? 1.1148 1.6691 1.0301 -0.0198 -0.2060 0.0874  273 GLN A C   
297  O O   . GLN A 58  ? 1.1288 1.7042 0.9854 -0.0461 -0.2199 0.0894  273 GLN A O   
298  C CB  . GLN A 58  ? 1.1066 1.6340 1.0736 0.0495  -0.2285 0.1762  273 GLN A CB  
299  C CG  . GLN A 58  ? 1.0882 1.6464 1.1220 0.0921  -0.2476 0.2144  273 GLN A CG  
300  C CD  . GLN A 58  ? 1.2079 1.7580 1.2041 0.1156  -0.2757 0.2752  273 GLN A CD  
301  O OE1 . GLN A 58  ? 1.2522 1.8702 1.2172 0.1057  -0.3130 0.2930  273 GLN A OE1 
302  N NE2 . GLN A 58  ? 1.2052 1.6656 1.1962 0.1454  -0.2556 0.3073  273 GLN A NE2 
303  N N   . ILE A 59  ? 1.1641 1.6578 1.0887 -0.0185 -0.1698 0.0514  274 ILE A N   
304  C CA  . ILE A 59  ? 1.1904 1.6378 1.0590 -0.0404 -0.1468 0.0150  274 ILE A CA  
305  C C   . ILE A 59  ? 1.2135 1.6803 1.0848 -0.0645 -0.1301 -0.0364 274 ILE A C   
306  O O   . ILE A 59  ? 1.2475 1.6645 1.0798 -0.0730 -0.1059 -0.0701 274 ILE A O   
307  C CB  . ILE A 59  ? 1.1695 1.5212 1.0280 -0.0175 -0.1184 0.0139  274 ILE A CB  
308  C CG1 . ILE A 59  ? 1.1434 1.4575 1.0484 0.0012  -0.0932 -0.0055 274 ILE A CG1 
309  C CG2 . ILE A 59  ? 1.1526 1.4757 1.0071 0.0029  -0.1272 0.0616  274 ILE A CG2 
310  C CD1 . ILE A 59  ? 1.0972 1.3253 1.0035 0.0282  -0.0702 0.0033  274 ILE A CD1 
311  N N   . TYR A 60  ? 1.2185 1.7557 1.1345 -0.0748 -0.1404 -0.0453 275 TYR A N   
312  C CA  . TYR A 60  ? 1.2419 1.7910 1.1561 -0.1031 -0.1177 -0.0972 275 TYR A CA  
313  C C   . TYR A 60  ? 1.2621 1.8100 1.1089 -0.1350 -0.1129 -0.1244 275 TYR A C   
314  O O   . TYR A 60  ? 1.2638 1.7663 1.0842 -0.1467 -0.0813 -0.1666 275 TYR A O   
315  C CB  . TYR A 60  ? 1.2004 1.8495 1.1697 -0.1192 -0.1348 -0.1042 275 TYR A CB  
316  C CG  . TYR A 60  ? 1.1650 1.8092 1.2048 -0.1023 -0.1162 -0.1146 275 TYR A CG  
317  C CD1 . TYR A 60  ? 1.1739 1.7232 1.2236 -0.0713 -0.0885 -0.1091 275 TYR A CD1 
318  C CD2 . TYR A 60  ? 1.1476 1.8871 1.2450 -0.1205 -0.1248 -0.1342 275 TYR A CD2 
319  C CE1 . TYR A 60  ? 1.1662 1.7093 1.2790 -0.0595 -0.0677 -0.1213 275 TYR A CE1 
320  C CE2 . TYR A 60  ? 1.1619 1.9029 1.3286 -0.1088 -0.1044 -0.1491 275 TYR A CE2 
321  C CZ  . TYR A 60  ? 1.1931 1.8320 1.3661 -0.0785 -0.0746 -0.1419 275 TYR A CZ  
322  O OH  . TYR A 60  ? 1.1879 1.8252 1.4281 -0.0702 -0.0504 -0.1592 275 TYR A OH  
323  N N   . ASP A 61  ? 1.2174 1.8086 1.0317 -0.1481 -0.1417 -0.1004 276 ASP A N   
324  C CA  . ASP A 61  ? 1.2430 1.8518 0.9990 -0.1840 -0.1400 -0.1262 276 ASP A CA  
325  C C   . ASP A 61  ? 1.2619 1.7940 0.9706 -0.1760 -0.1183 -0.1400 276 ASP A C   
326  O O   . ASP A 61  ? 1.2550 1.7907 0.9208 -0.2021 -0.1075 -0.1720 276 ASP A O   
327  C CB  . ASP A 61  ? 1.1779 1.8625 0.9131 -0.2032 -0.1789 -0.0945 276 ASP A CB  
328  C CG  . ASP A 61  ? 1.1522 1.8034 0.8703 -0.1782 -0.1949 -0.0450 276 ASP A CG  
329  O OD1 . ASP A 61  ? 1.1813 1.7707 0.9249 -0.1429 -0.1826 -0.0286 276 ASP A OD1 
330  O OD2 . ASP A 61  ? 1.1782 1.8620 0.8537 -0.1958 -0.2180 -0.0223 276 ASP A OD2 
331  N N   . LYS A 62  ? 1.2014 1.6705 0.9191 -0.1414 -0.1114 -0.1192 277 LYS A N   
332  C CA  . LYS A 62  ? 1.1805 1.5871 0.8608 -0.1312 -0.0929 -0.1355 277 LYS A CA  
333  C C   . LYS A 62  ? 1.1903 1.5341 0.8671 -0.1151 -0.0613 -0.1745 277 LYS A C   
334  O O   . LYS A 62  ? 1.1666 1.4573 0.8188 -0.0971 -0.0473 -0.1889 277 LYS A O   
335  C CB  . LYS A 62  ? 1.1404 1.5111 0.8266 -0.1062 -0.0988 -0.0981 277 LYS A CB  
336  C CG  . LYS A 62  ? 1.1670 1.5829 0.8464 -0.1171 -0.1276 -0.0535 277 LYS A CG  
337  C CD  . LYS A 62  ? 1.1543 1.5401 0.7908 -0.1223 -0.1234 -0.0446 277 LYS A CD  
338  C CE  . LYS A 62  ? 1.1601 1.5349 0.7948 -0.1111 -0.1382 0.0098  277 LYS A CE  
339  N NZ  . LYS A 62  ? 1.1431 1.4594 0.7511 -0.1073 -0.1190 0.0119  277 LYS A NZ  
340  N N   . PHE A 63  ? 1.4203 1.4853 1.0837 0.1255  0.0352  -0.2693 278 PHE A N   
341  C CA  . PHE A 63  ? 1.4644 1.4784 1.1805 0.1295  0.0319  -0.2653 278 PHE A CA  
342  C C   . PHE A 63  ? 1.6284 1.5388 1.2818 0.0883  -0.0040 -0.2972 278 PHE A C   
343  O O   . PHE A 63  ? 1.6362 1.5443 1.2293 0.0460  -0.0380 -0.3089 278 PHE A O   
344  C CB  . PHE A 63  ? 1.3459 1.4383 1.1669 0.1177  0.0195  -0.2092 278 PHE A CB  
345  C CG  . PHE A 63  ? 1.1792 1.3728 1.0524 0.1478  0.0522  -0.1766 278 PHE A CG  
346  C CD1 . PHE A 63  ? 1.1268 1.3941 0.9886 0.1356  0.0485  -0.1575 278 PHE A CD1 
347  C CD2 . PHE A 63  ? 1.0329 1.2455 0.9657 0.1850  0.0836  -0.1625 278 PHE A CD2 
348  C CE1 . PHE A 63  ? 1.0172 1.3635 0.9181 0.1590  0.0811  -0.1292 278 PHE A CE1 
349  C CE2 . PHE A 63  ? 0.8891 1.1889 0.8635 0.2040  0.1119  -0.1350 278 PHE A CE2 
350  C CZ  . PHE A 63  ? 0.8976 1.2594 0.8536 0.1900  0.1130  -0.1196 278 PHE A CZ  
351  N N   . PRO A 64  ? 1.9672 1.7863 1.6262 0.0969  0.0006  -0.3121 279 PRO A N   
352  C CA  . PRO A 64  ? 2.0539 1.7540 1.6374 0.0569  -0.0270 -0.3495 279 PRO A CA  
353  C C   . PRO A 64  ? 2.0455 1.7738 1.6593 -0.0119 -0.0811 -0.3231 279 PRO A C   
354  O O   . PRO A 64  ? 1.9653 1.7607 1.6739 -0.0197 -0.0895 -0.2763 279 PRO A O   
355  C CB  . PRO A 64  ? 2.1025 1.7052 1.6999 0.0935  -0.0013 -0.3612 279 PRO A CB  
356  C CG  . PRO A 64  ? 1.9838 1.6780 1.6941 0.1248  0.0132  -0.3096 279 PRO A CG  
357  C CD  . PRO A 64  ? 1.9208 1.7383 1.6537 0.1423  0.0296  -0.2925 279 PRO A CD  
358  N N   . GLU A 65  ? 1.8997 1.5777 1.4311 -0.0641 -0.1172 -0.3541 280 GLU A N   
359  C CA  . GLU A 65  ? 1.8524 1.5498 1.4136 -0.1348 -0.1705 -0.3342 280 GLU A CA  
360  C C   . GLU A 65  ? 1.8605 1.4430 1.4234 -0.1545 -0.1729 -0.3458 280 GLU A C   
361  O O   . GLU A 65  ? 1.8672 1.4066 1.4091 -0.2210 -0.2132 -0.3546 280 GLU A O   
362  C CB  . GLU A 65  ? 1.8707 1.5665 1.3460 -0.1894 -0.2150 -0.3601 280 GLU A CB  
363  C CG  . GLU A 65  ? 1.8235 1.6363 1.2979 -0.1751 -0.2195 -0.3397 280 GLU A CG  
364  C CD  . GLU A 65  ? 1.7063 1.6620 1.2985 -0.1902 -0.2433 -0.2762 280 GLU A CD  
365  O OE1 . GLU A 65  ? 1.6410 1.6909 1.2342 -0.1870 -0.2560 -0.2540 280 GLU A OE1 
366  O OE2 . GLU A 65  ? 1.6578 1.6262 1.3382 -0.2033 -0.2461 -0.2475 280 GLU A OE2 
367  N N   . LYS A 66  ? 1.9147 1.4488 1.5030 -0.0979 -0.1305 -0.3438 281 LYS A N   
368  C CA  . LYS A 66  ? 1.8709 1.2855 1.4562 -0.1046 -0.1265 -0.3511 281 LYS A CA  
369  C C   . LYS A 66  ? 1.7559 1.2339 1.4544 -0.0976 -0.1235 -0.2942 281 LYS A C   
370  O O   . LYS A 66  ? 1.6732 1.2795 1.4485 -0.0785 -0.1169 -0.2538 281 LYS A O   
371  C CB  . LYS A 66  ? 1.8165 1.1139 1.3394 -0.0415 -0.0812 -0.3909 281 LYS A CB  
372  N N   . LYS A 67  ? 1.6493 1.0255 1.3483 -0.1165 -0.1271 -0.2921 282 LYS A N   
373  C CA  . LYS A 67  ? 1.6000 1.0087 1.3884 -0.1102 -0.1212 -0.2414 282 LYS A CA  
374  C C   . LYS A 67  ? 1.5408 1.0313 1.3863 -0.0367 -0.0861 -0.2146 282 LYS A C   
375  O O   . LYS A 67  ? 1.5591 1.0107 1.3710 0.0233  -0.0559 -0.2395 282 LYS A O   
376  C CB  . LYS A 67  ? 1.6868 0.9405 1.4412 -0.1171 -0.1164 -0.2512 282 LYS A CB  
377  N N   . GLY A 68  ? 1.4911 1.0961 1.4232 -0.0438 -0.0888 -0.1643 283 GLY A N   
378  C CA  . GLY A 68  ? 1.3549 1.0510 1.3392 0.0128  -0.0598 -0.1381 283 GLY A CA  
379  C C   . GLY A 68  ? 1.3477 1.1327 1.3187 0.0326  -0.0503 -0.1517 283 GLY A C   
380  O O   . GLY A 68  ? 1.3157 1.1499 1.3071 0.0850  -0.0203 -0.1458 283 GLY A O   
381  N N   . GLY A 69  ? 1.3645 1.1702 1.2988 -0.0094 -0.0758 -0.1693 284 GLY A N   
382  C CA  . GLY A 69  ? 1.3549 1.2496 1.2763 0.0046  -0.0693 -0.1734 284 GLY A CA  
383  C C   . GLY A 69  ? 1.1890 1.2092 1.1843 -0.0155 -0.0792 -0.1247 284 GLY A C   
384  O O   . GLY A 69  ? 1.1552 1.1943 1.2082 -0.0485 -0.0946 -0.0918 284 GLY A O   
385  N N   . LEU A 70  ? 1.1746 1.2756 1.1643 0.0057  -0.0661 -0.1200 285 LEU A N   
386  C CA  . LEU A 70  ? 1.0852 1.2992 1.1374 -0.0068 -0.0706 -0.0744 285 LEU A CA  
387  C C   . LEU A 70  ? 1.0807 1.3197 1.1555 -0.0658 -0.1147 -0.0591 285 LEU A C   
388  O O   . LEU A 70  ? 1.0300 1.3195 1.1810 -0.0855 -0.1186 -0.0184 285 LEU A O   
389  C CB  . LEU A 70  ? 1.0669 1.3431 1.0876 0.0199  -0.0533 -0.0777 285 LEU A CB  
390  C CG  . LEU A 70  ? 0.9792 1.3608 1.0629 0.0263  -0.0399 -0.0291 285 LEU A CG  
391  C CD1 . LEU A 70  ? 0.8856 1.2780 1.0410 0.0373  -0.0175 0.0027  285 LEU A CD1 
392  C CD2 . LEU A 70  ? 0.9770 1.3970 1.0228 0.0609  -0.0104 -0.0350 285 LEU A CD2 
393  N N   . ARG A 71  ? 1.0861 1.2933 1.0950 -0.0964 -0.1477 -0.0915 286 ARG A N   
394  C CA  . ARG A 71  ? 1.1020 1.3435 1.1342 -0.1571 -0.1955 -0.0786 286 ARG A CA  
395  C C   . ARG A 71  ? 1.0672 1.2767 1.1591 -0.1919 -0.2035 -0.0613 286 ARG A C   
396  O O   . ARG A 71  ? 1.0129 1.3016 1.1877 -0.2181 -0.2141 -0.0192 286 ARG A O   
397  C CB  . ARG A 71  ? 1.1924 1.3746 1.1264 -0.1895 -0.2311 -0.1256 286 ARG A CB  
398  N N   . GLU A 72  ? 1.1313 1.2203 1.1797 -0.1906 -0.1949 -0.0924 287 GLU A N   
399  C CA  . GLU A 72  ? 1.1286 1.1674 1.2184 -0.2247 -0.2004 -0.0778 287 GLU A CA  
400  C C   . GLU A 72  ? 1.0631 1.1730 1.2468 -0.2064 -0.1738 -0.0246 287 GLU A C   
401  O O   . GLU A 72  ? 1.0210 1.1797 1.2722 -0.2479 -0.1866 0.0086  287 GLU A O   
402  C CB  . GLU A 72  ? 1.2350 1.1250 1.2564 -0.2077 -0.1854 -0.1165 287 GLU A CB  
403  C CG  . GLU A 72  ? 1.2794 1.0945 1.3277 -0.2378 -0.1866 -0.1023 287 GLU A CG  
404  C CD  . GLU A 72  ? 1.4150 1.0679 1.3757 -0.2420 -0.1867 -0.1482 287 GLU A CD  
405  O OE1 . GLU A 72  ? 1.4736 1.0718 1.3711 -0.2903 -0.2161 -0.1847 287 GLU A OE1 
406  O OE2 . GLU A 72  ? 1.4691 1.0465 1.4215 -0.1957 -0.1570 -0.1472 287 GLU A OE2 
407  N N   . LEU A 73  ? 1.0946 1.2123 1.2823 -0.1467 -0.1354 -0.0165 288 LEU A N   
408  C CA  . LEU A 73  ? 1.0657 1.2324 1.3254 -0.1306 -0.1086 0.0295  288 LEU A CA  
409  C C   . LEU A 73  ? 0.9679 1.2571 1.2954 -0.1487 -0.1117 0.0698  288 LEU A C   
410  O O   . LEU A 73  ? 0.9602 1.2796 1.3515 -0.1745 -0.1078 0.1059  288 LEU A O   
411  C CB  . LEU A 73  ? 1.0347 1.1986 1.2811 -0.0674 -0.0718 0.0276  288 LEU A CB  
412  C CG  . LEU A 73  ? 1.0981 1.1492 1.3009 -0.0403 -0.0625 0.0009  288 LEU A CG  
413  C CD1 . LEU A 73  ? 1.0569 1.1268 1.2584 0.0214  -0.0293 0.0005  288 LEU A CD1 
414  C CD2 . LEU A 73  ? 1.0923 1.0842 1.3220 -0.0664 -0.0670 0.0242  288 LEU A CD2 
415  N N   . TYR A 74  ? 0.9087 1.2666 1.2218 -0.1324 -0.1148 0.0659  289 TYR A N   
416  C CA  . TYR A 74  ? 0.8152 1.2861 1.1918 -0.1407 -0.1149 0.1068  289 TYR A CA  
417  C C   . TYR A 74  ? 0.8128 1.3168 1.2446 -0.1986 -0.1476 0.1251  289 TYR A C   
418  O O   . TYR A 74  ? 0.7596 1.3426 1.2691 -0.2073 -0.1369 0.1680  289 TYR A O   
419  C CB  . TYR A 74  ? 0.7991 1.3242 1.1385 -0.1199 -0.1216 0.0977  289 TYR A CB  
420  C CG  . TYR A 74  ? 0.7169 1.3480 1.1163 -0.1080 -0.1069 0.1435  289 TYR A CG  
421  C CD1 . TYR A 74  ? 0.6830 1.3352 1.0914 -0.0662 -0.0614 0.1628  289 TYR A CD1 
422  C CD2 . TYR A 74  ? 0.7189 1.4279 1.1676 -0.1388 -0.1378 0.1686  289 TYR A CD2 
423  C CE1 . TYR A 74  ? 0.6566 1.3825 1.1064 -0.0533 -0.0422 0.2019  289 TYR A CE1 
424  C CE2 . TYR A 74  ? 0.6988 1.4957 1.2017 -0.1206 -0.1197 0.2117  289 TYR A CE2 
425  C CZ  . TYR A 74  ? 0.6840 1.4418 1.1552 -0.0736 -0.0662 0.2179  289 TYR A CZ  
426  O OH  . TYR A 74  ? 0.6993 1.4434 1.1541 -0.0506 -0.0405 0.2384  289 TYR A OH  
427  N N   . ASP A 75  ? 0.9131 1.3566 1.3061 -0.2401 -0.1848 0.0924  290 ASP A N   
428  C CA  . ASP A 75  ? 0.8983 1.3793 1.3451 -0.3034 -0.2197 0.1071  290 ASP A CA  
429  C C   . ASP A 75  ? 0.8599 1.3317 1.3753 -0.3238 -0.1976 0.1394  290 ASP A C   
430  O O   . ASP A 75  ? 0.7981 1.3544 1.3974 -0.3568 -0.2040 0.1748  290 ASP A O   
431  C CB  . ASP A 75  ? 0.9807 1.3799 1.3565 -0.3481 -0.2616 0.0601  290 ASP A CB  
432  C CG  . ASP A 75  ? 1.0013 1.4589 1.3436 -0.3616 -0.3020 0.0455  290 ASP A CG  
433  O OD1 . ASP A 75  ? 0.9907 1.4244 1.2582 -0.3207 -0.2936 0.0200  290 ASP A OD1 
434  O OD2 . ASP A 75  ? 1.0393 1.5736 1.4327 -0.4122 -0.3414 0.0624  290 ASP A OD2 
435  N N   . ARG A 76  ? 0.8987 1.2694 1.3799 -0.3047 -0.1713 0.1291  291 ARG A N   
436  C CA  . ARG A 76  ? 0.8589 1.2130 1.3929 -0.3225 -0.1481 0.1618  291 ARG A CA  
437  C C   . ARG A 76  ? 0.7630 1.2137 1.3642 -0.2943 -0.1123 0.2080  291 ARG A C   
438  O O   . ARG A 76  ? 0.7416 1.2487 1.4111 -0.3215 -0.1039 0.2410  291 ARG A O   
439  C CB  . ARG A 76  ? 0.9481 1.1711 1.4231 -0.3013 -0.1304 0.1437  291 ARG A CB  
440  C CG  . ARG A 76  ? 1.0621 1.1867 1.5204 -0.3554 -0.1479 0.1319  291 ARG A CG  
441  C CD  . ARG A 76  ? 1.1893 1.1746 1.5750 -0.3241 -0.1347 0.1091  291 ARG A CD  
442  N NE  . ARG A 76  ? 1.2934 1.2168 1.6006 -0.3039 -0.1511 0.0587  291 ARG A NE  
443  C CZ  . ARG A 76  ? 1.3702 1.1992 1.6159 -0.2542 -0.1356 0.0347  291 ARG A CZ  
444  N NH1 . ARG A 76  ? 1.3837 1.1695 1.6359 -0.2193 -0.1095 0.0572  291 ARG A NH1 
445  N NH2 . ARG A 76  ? 1.3762 1.1545 1.5517 -0.2382 -0.1462 -0.0123 291 ARG A NH2 
446  N N   . GLY A 77  ? 0.7534 1.2175 1.3272 -0.2379 -0.0870 0.2072  292 GLY A N   
447  C CA  . GLY A 77  ? 0.6702 1.2081 1.2895 -0.2103 -0.0499 0.2456  292 GLY A CA  
448  C C   . GLY A 77  ? 0.6904 1.1635 1.2899 -0.1880 -0.0140 0.2563  292 GLY A C   
449  O O   . GLY A 77  ? 0.7435 1.1301 1.3122 -0.1931 -0.0196 0.2420  292 GLY A O   
450  N N   . PRO A 78  ? 0.6514 1.1144 1.2109 -0.1493 0.0185  0.2611  293 PRO A N   
451  C CA  . PRO A 78  ? 0.6165 1.1118 1.1592 -0.1293 0.0259  0.2608  293 PRO A CA  
452  C C   . PRO A 78  ? 0.6005 1.1190 1.1099 -0.0966 0.0275  0.2498  293 PRO A C   
453  O O   . PRO A 78  ? 0.6103 1.1044 1.0842 -0.0715 0.0400  0.2396  293 PRO A O   
454  C CB  . PRO A 78  ? 0.6515 1.0984 1.1589 -0.1103 0.0534  0.2652  293 PRO A CB  
455  C CG  . PRO A 78  ? 0.6728 1.0714 1.1530 -0.0985 0.0630  0.2626  293 PRO A CG  
456  C CD  . PRO A 78  ? 0.6610 1.0637 1.1877 -0.1304 0.0438  0.2675  293 PRO A CD  
457  N N   . PRO A 79  ? 0.7692 1.0154 1.1486 -0.0517 0.1172  0.1624  294 PRO A N   
458  C CA  . PRO A 79  ? 0.7811 1.0218 1.1574 -0.0374 0.0818  0.1559  294 PRO A CA  
459  C C   . PRO A 79  ? 0.7707 0.9688 1.1064 0.0048  0.0884  0.1429  294 PRO A C   
460  O O   . PRO A 79  ? 0.7883 0.9452 1.0848 0.0084  0.0657  0.1324  294 PRO A O   
461  C CB  . PRO A 79  ? 0.7374 1.0679 1.2012 -0.0357 0.0681  0.1724  294 PRO A CB  
462  C CG  . PRO A 79  ? 0.6913 1.0821 1.2106 -0.0518 0.0955  0.1857  294 PRO A CG  
463  C CD  . PRO A 79  ? 0.7373 1.0711 1.2018 -0.0655 0.1280  0.1792  294 PRO A CD  
464  N N   . HIS A 80  ? 0.7660 0.9717 1.1069 0.0337  0.1207  0.1416  295 HIS A N   
465  C CA  . HIS A 80  ? 0.7561 0.9212 1.0554 0.0681  0.1287  0.1249  295 HIS A CA  
466  C C   . HIS A 80  ? 0.7886 0.8914 1.0078 0.0648  0.1251  0.1099  295 HIS A C   
467  O O   . HIS A 80  ? 0.7890 0.8620 0.9716 0.0856  0.1261  0.0933  295 HIS A O   
468  C CB  . HIS A 80  ? 0.7520 0.9359 1.0669 0.0968  0.1683  0.1244  295 HIS A CB  
469  C CG  . HIS A 80  ? 0.7852 0.9539 1.0599 0.0916  0.1990  0.1241  295 HIS A CG  
470  N ND1 . HIS A 80  ? 0.7903 0.9996 1.1030 0.0748  0.2222  0.1419  295 HIS A ND1 
471  C CD2 . HIS A 80  ? 0.8163 0.9359 1.0146 0.0999  0.2096  0.1108  295 HIS A CD2 
472  C CE1 . HIS A 80  ? 0.8466 1.0238 1.1035 0.0748  0.2487  0.1409  295 HIS A CE1 
473  N NE2 . HIS A 80  ? 0.8559 0.9814 1.0422 0.0917  0.2397  0.1229  295 HIS A NE2 
474  N N   . ALA A 81  ? 0.7841 0.8665 0.9752 0.0401  0.1224  0.1153  296 ALA A N   
475  C CA  . ALA A 81  ? 0.8421 0.8728 0.9628 0.0433  0.1193  0.1064  296 ALA A CA  
476  C C   . ALA A 81  ? 0.8535 0.8584 0.9551 0.0361  0.0874  0.0983  296 ALA A C   
477  O O   . ALA A 81  ? 0.8253 0.7965 0.8757 0.0428  0.0840  0.0917  296 ALA A O   
478  C CB  . ALA A 81  ? 0.8302 0.8398 0.9242 0.0262  0.1376  0.1193  296 ALA A CB  
479  N N   . PHE A 82  ? 0.8286 0.8525 0.9691 0.0245  0.0650  0.1007  297 PHE A N   
480  C CA  . PHE A 82  ? 0.8576 0.8563 0.9779 0.0104  0.0383  0.0967  297 PHE A CA  
481  C C   . PHE A 82  ? 0.8572 0.8519 0.9786 0.0269  0.0223  0.0871  297 PHE A C   
482  O O   . PHE A 82  ? 0.8097 0.8302 0.9702 0.0396  0.0219  0.0903  297 PHE A O   
483  C CB  . PHE A 82  ? 0.8546 0.8735 1.0056 -0.0209 0.0228  0.1069  297 PHE A CB  
484  C CG  . PHE A 82  ? 0.8890 0.8906 1.0244 -0.0477 0.0373  0.1123  297 PHE A CG  
485  C CD1 . PHE A 82  ? 0.8745 0.8998 1.0338 -0.0507 0.0632  0.1216  297 PHE A CD1 
486  C CD2 . PHE A 82  ? 0.9017 0.8559 0.9942 -0.0698 0.0297  0.1081  297 PHE A CD2 
487  C CE1 . PHE A 82  ? 0.9261 0.9260 1.0675 -0.0783 0.0806  0.1276  297 PHE A CE1 
488  C CE2 . PHE A 82  ? 0.9649 0.8883 1.0369 -0.0952 0.0478  0.1123  297 PHE A CE2 
489  C CZ  . PHE A 82  ? 0.9677 0.9126 1.0641 -0.1009 0.0729  0.1225  297 PHE A CZ  
490  N N   . PHE A 83  ? 0.8753 0.8364 0.9552 0.0270  0.0118  0.0771  298 PHE A N   
491  C CA  . PHE A 83  ? 0.8571 0.8073 0.9307 0.0380  0.0013  0.0664  298 PHE A CA  
492  C C   . PHE A 83  ? 0.8885 0.8155 0.9375 0.0246  -0.0168 0.0648  298 PHE A C   
493  O O   . PHE A 83  ? 0.8601 0.7698 0.8814 0.0150  -0.0157 0.0662  298 PHE A O   
494  C CB  . PHE A 83  ? 0.8675 0.8084 0.9127 0.0544  0.0142  0.0507  298 PHE A CB  
495  C CG  . PHE A 83  ? 0.8887 0.8448 0.9478 0.0697  0.0356  0.0481  298 PHE A CG  
496  C CD1 . PHE A 83  ? 0.8602 0.8262 0.9098 0.0722  0.0540  0.0545  298 PHE A CD1 
497  C CD2 . PHE A 83  ? 0.8820 0.8358 0.9594 0.0829  0.0416  0.0401  298 PHE A CD2 
498  C CE1 . PHE A 83  ? 0.8713 0.8508 0.9302 0.0867  0.0774  0.0521  298 PHE A CE1 
499  C CE2 . PHE A 83  ? 0.9067 0.8693 0.9925 0.0998  0.0669  0.0360  298 PHE A CE2 
500  C CZ  . PHE A 83  ? 0.8535 0.8320 0.9306 0.1012  0.0844  0.0417  298 PHE A CZ  
501  N N   . LEU A 84  ? 0.8888 0.8100 0.9449 0.0259  -0.0295 0.0630  299 LEU A N   
502  C CA  . LEU A 84  ? 0.8556 0.7542 0.8856 0.0155  -0.0424 0.0604  299 LEU A CA  
503  C C   . LEU A 84  ? 0.8390 0.7260 0.8552 0.0243  -0.0381 0.0459  299 LEU A C   
504  O O   . LEU A 84  ? 0.8259 0.7125 0.8570 0.0340  -0.0324 0.0404  299 LEU A O   
505  C CB  . LEU A 84  ? 0.8980 0.7993 0.9427 0.0058  -0.0605 0.0728  299 LEU A CB  
506  C CG  . LEU A 84  ? 0.8950 0.7715 0.9115 -0.0044 -0.0725 0.0728  299 LEU A CG  
507  C CD1 . LEU A 84  ? 0.9047 0.7632 0.8857 -0.0203 -0.0728 0.0696  299 LEU A CD1 
508  C CD2 . LEU A 84  ? 0.8942 0.7808 0.9277 -0.0070 -0.0899 0.0891  299 LEU A CD2 
509  N N   . VAL A 85  ? 0.8929 0.7711 0.8814 0.0202  -0.0386 0.0391  300 VAL A N   
510  C CA  . VAL A 85  ? 0.8858 0.7616 0.8658 0.0200  -0.0378 0.0255  300 VAL A CA  
511  C C   . VAL A 85  ? 0.8721 0.7326 0.8399 0.0084  -0.0450 0.0297  300 VAL A C   
512  O O   . VAL A 85  ? 0.8196 0.6765 0.7691 0.0060  -0.0447 0.0343  300 VAL A O   
513  C CB  . VAL A 85  ? 0.8474 0.7437 0.8112 0.0274  -0.0312 0.0149  300 VAL A CB  
514  C CG1 . VAL A 85  ? 0.8461 0.7504 0.8058 0.0191  -0.0337 0.0002  300 VAL A CG1 
515  C CG2 . VAL A 85  ? 0.8469 0.7551 0.8133 0.0385  -0.0219 0.0098  300 VAL A CG2 
516  N N   . LYS A 86  ? 0.8924 0.7373 0.8659 0.0022  -0.0479 0.0290  301 LYS A N   
517  C CA  . LYS A 86  ? 0.8883 0.7192 0.8458 -0.0095 -0.0499 0.0312  301 LYS A CA  
518  C C   . LYS A 86  ? 0.8937 0.7376 0.8504 -0.0155 -0.0422 0.0151  301 LYS A C   
519  O O   . LYS A 86  ? 0.8900 0.7325 0.8561 -0.0180 -0.0380 0.0024  301 LYS A O   
520  C CB  . LYS A 86  ? 0.9078 0.7124 0.8664 -0.0142 -0.0560 0.0440  301 LYS A CB  
521  C CG  . LYS A 86  ? 0.9410 0.7291 0.8723 -0.0267 -0.0581 0.0516  301 LYS A CG  
522  C CD  . LYS A 86  ? 1.0258 0.7929 0.9490 -0.0285 -0.0696 0.0714  301 LYS A CD  
523  C CE  . LYS A 86  ? 1.0541 0.8010 0.9397 -0.0415 -0.0700 0.0789  301 LYS A CE  
524  N NZ  . LYS A 86  ? 1.0775 0.8255 0.9405 -0.0471 -0.0857 0.0887  301 LYS A NZ  
525  N N   . PHE A 87  ? 0.8180 0.6766 0.7636 -0.0183 -0.0391 0.0149  302 PHE A N   
526  C CA  . PHE A 87  ? 0.8392 0.7295 0.7915 -0.0249 -0.0338 0.0022  302 PHE A CA  
527  C C   . PHE A 87  ? 0.8909 0.7699 0.8398 -0.0411 -0.0277 0.0048  302 PHE A C   
528  O O   . PHE A 87  ? 0.8297 0.6884 0.7608 -0.0399 -0.0252 0.0174  302 PHE A O   
529  C CB  . PHE A 87  ? 0.8222 0.7501 0.7712 -0.0090 -0.0313 0.0042  302 PHE A CB  
530  C CG  . PHE A 87  ? 0.8134 0.7689 0.7657 0.0031  -0.0347 -0.0024 302 PHE A CG  
531  C CD1 . PHE A 87  ? 0.8214 0.7925 0.7819 -0.0076 -0.0383 -0.0200 302 PHE A CD1 
532  C CD2 . PHE A 87  ? 0.8143 0.7743 0.7547 0.0237  -0.0319 0.0086  302 PHE A CD2 
533  C CE1 . PHE A 87  ? 0.8030 0.7988 0.7574 0.0029  -0.0408 -0.0270 302 PHE A CE1 
534  C CE2 . PHE A 87  ? 0.8192 0.8034 0.7561 0.0360  -0.0333 0.0055  302 PHE A CE2 
535  C CZ  . PHE A 87  ? 0.8113 0.8158 0.7541 0.0259  -0.0388 -0.0124 302 PHE A CZ  
536  N N   . TRP A 88  ? 0.8616 0.7517 0.8236 -0.0592 -0.0233 -0.0084 303 TRP A N   
537  C CA  . TRP A 88  ? 0.9084 0.8015 0.8724 -0.0778 -0.0129 -0.0075 303 TRP A CA  
538  C C   . TRP A 88  ? 0.8756 0.8378 0.8620 -0.0824 -0.0112 -0.0194 303 TRP A C   
539  O O   . TRP A 88  ? 0.8220 0.8093 0.8235 -0.0999 -0.0144 -0.0379 303 TRP A O   
540  C CB  . TRP A 88  ? 0.8917 0.7395 0.8535 -0.0996 -0.0065 -0.0106 303 TRP A CB  
541  C CG  . TRP A 88  ? 0.9361 0.7284 0.8778 -0.0888 -0.0099 0.0086  303 TRP A CG  
542  C CD1 . TRP A 88  ? 0.9582 0.7216 0.8778 -0.0911 -0.0063 0.0271  303 TRP A CD1 
543  C CD2 . TRP A 88  ? 0.9971 0.7645 0.9396 -0.0729 -0.0185 0.0131  303 TRP A CD2 
544  N NE1 . TRP A 88  ? 0.9974 0.7245 0.9041 -0.0784 -0.0164 0.0436  303 TRP A NE1 
545  C CE2 . TRP A 88  ? 1.0150 0.7471 0.9405 -0.0662 -0.0231 0.0361  303 TRP A CE2 
546  C CE3 . TRP A 88  ? 0.9560 0.7314 0.9115 -0.0632 -0.0214 0.0006  303 TRP A CE3 
547  C CZ2 . TRP A 88  ? 1.0780 0.7924 1.0084 -0.0490 -0.0324 0.0489  303 TRP A CZ2 
548  C CZ3 . TRP A 88  ? 0.9748 0.7254 0.9336 -0.0454 -0.0257 0.0122  303 TRP A CZ3 
549  C CH2 . TRP A 88  ? 1.0503 0.7755 1.0011 -0.0380 -0.0319 0.0369  303 TRP A CH2 
550  N N   . ALA A 89  ? 0.8119 0.8057 0.7989 -0.0659 -0.0059 -0.0088 304 ALA A N   
551  C CA  . ALA A 89  ? 0.8059 0.8770 0.8179 -0.0582 -0.0063 -0.0129 304 ALA A CA  
552  C C   . ALA A 89  ? 0.8145 0.9294 0.8535 -0.0818 0.0046  -0.0173 304 ALA A C   
553  O O   . ALA A 89  ? 0.7728 0.8562 0.8034 -0.0926 0.0199  -0.0095 304 ALA A O   
554  C CB  . ALA A 89  ? 0.7799 0.8605 0.7806 -0.0228 -0.0009 0.0033  304 ALA A CB  
555  N N   . ASP A 90  ? 0.7777 0.9703 0.8484 -0.0914 -0.0035 -0.0293 305 ASP A N   
556  C CA  . ASP A 90  ? 0.7595 1.0187 0.8680 -0.1166 0.0048  -0.0345 305 ASP A CA  
557  C C   . ASP A 90  ? 0.7739 1.1007 0.9036 -0.0823 0.0136  -0.0158 305 ASP A C   
558  O O   . ASP A 90  ? 0.7413 1.1245 0.8811 -0.0549 0.0012  -0.0110 305 ASP A O   
559  C CB  . ASP A 90  ? 0.7375 1.0523 0.8684 -0.1482 -0.0119 -0.0593 305 ASP A CB  
560  C CG  . ASP A 90  ? 0.7680 1.1514 0.9416 -0.1872 -0.0045 -0.0688 305 ASP A CG  
561  O OD1 . ASP A 90  ? 0.8019 1.2154 0.9972 -0.1792 0.0138  -0.0520 305 ASP A OD1 
562  O OD2 . ASP A 90  ? 0.7685 1.1776 0.9534 -0.2278 -0.0152 -0.0944 305 ASP A OD2 
563  N N   . LEU A 91  ? 0.7730 1.0899 0.9050 -0.0797 0.0376  -0.0030 306 LEU A N   
564  C CA  . LEU A 91  ? 0.8037 1.1789 0.9557 -0.0434 0.0533  0.0152  306 LEU A CA  
565  C C   . LEU A 91  ? 0.8119 1.2845 1.0213 -0.0631 0.0654  0.0149  306 LEU A C   
566  O O   . LEU A 91  ? 0.8033 1.3188 1.0326 -0.0356 0.0880  0.0317  306 LEU A O   
567  C CB  . LEU A 91  ? 0.7969 1.0906 0.9037 -0.0187 0.0765  0.0300  306 LEU A CB  
568  C CG  . LEU A 91  ? 0.8130 1.0177 0.8683 -0.0063 0.0636  0.0297  306 LEU A CG  
569  C CD1 . LEU A 91  ? 0.8234 0.9567 0.8320 0.0143  0.0841  0.0411  306 LEU A CD1 
570  C CD2 . LEU A 91  ? 0.7997 1.0400 0.8623 0.0208  0.0457  0.0315  306 LEU A CD2 
571  N N   . ASN A 92  ? 0.8310 1.3402 1.0683 -0.1111 0.0530  -0.0047 307 ASN A N   
572  C CA  . ASN A 92  ? 0.8174 1.4183 1.1126 -0.1439 0.0645  -0.0084 307 ASN A CA  
573  C C   . ASN A 92  ? 0.7957 1.5310 1.1439 -0.1380 0.0406  -0.0117 307 ASN A C   
574  O O   . ASN A 92  ? 0.7568 1.5151 1.1080 -0.1697 0.0136  -0.0340 307 ASN A O   
575  C CB  . ASN A 92  ? 0.8743 1.4238 1.1622 -0.2058 0.0677  -0.0290 307 ASN A CB  
576  C CG  . ASN A 92  ? 0.8897 1.5205 1.2342 -0.2484 0.0851  -0.0332 307 ASN A CG  
577  O OD1 . ASN A 92  ? 0.8958 1.5616 1.2651 -0.3008 0.0735  -0.0565 307 ASN A OD1 
578  N ND2 . ASN A 92  ? 0.8346 1.4923 1.1976 -0.2299 0.1160  -0.0123 307 ASN A ND2 
579  N N   . TRP A 93  ? 0.6885 1.5129 1.0755 -0.0957 0.0510  0.0112  308 TRP A N   
580  C CA  . TRP A 93  ? 0.5986 1.5656 1.0393 -0.0824 0.0267  0.0153  308 TRP A CA  
581  C C   . TRP A 93  ? 0.5251 1.5974 1.0247 -0.0438 0.0504  0.0431  308 TRP A C   
582  O O   . TRP A 93  ? 0.4894 1.6753 1.0574 -0.0746 0.0540  0.0406  308 TRP A O   
583  C CB  . TRP A 93  ? 0.5943 1.5390 0.9950 -0.0410 0.0006  0.0207  308 TRP A CB  
584  C CG  . TRP A 93  ? 0.5983 1.5271 0.9834 0.0330  0.0185  0.0536  308 TRP A CG  
585  C CD1 . TRP A 93  ? 0.5727 1.6080 0.9958 0.0844  0.0160  0.0801  308 TRP A CD1 
586  C CD2 . TRP A 93  ? 0.6500 1.4457 0.9750 0.0630  0.0434  0.0636  308 TRP A CD2 
587  N NE1 . TRP A 93  ? 0.5957 1.5592 0.9825 0.1454  0.0424  0.1054  308 TRP A NE1 
588  C CE2 . TRP A 93  ? 0.6503 1.4677 0.9759 0.1295  0.0586  0.0933  308 TRP A CE2 
589  C CE3 . TRP A 93  ? 0.6937 1.3569 0.9640 0.0398  0.0539  0.0512  308 TRP A CE3 
590  C CZ2 . TRP A 93  ? 0.6836 1.3858 0.9524 0.1666  0.0856  0.1057  308 TRP A CZ2 
591  C CZ3 . TRP A 93  ? 0.7174 1.2815 0.9357 0.0761  0.0752  0.0647  308 TRP A CZ3 
592  C CH2 . TRP A 93  ? 0.7211 1.3012 0.9369 0.1356  0.0915  0.0891  308 TRP A CH2 
593  N N   . SER A 107 ? 0.7206 2.1257 1.4017 0.1895  0.1402  0.1713  322 SER A N   
594  C CA  . SER A 107 ? 0.7859 2.0581 1.3953 0.2228  0.1647  0.1753  322 SER A CA  
595  C C   . SER A 107 ? 0.8531 2.0854 1.4159 0.2791  0.1460  0.1929  322 SER A C   
596  O O   . SER A 107 ? 0.8155 2.0119 1.3440 0.2643  0.1176  0.1805  322 SER A O   
597  C CB  . SER A 107 ? 0.7884 2.0006 1.3842 0.2552  0.2222  0.1884  322 SER A CB  
598  O OG  . SER A 107 ? 0.7437 1.9128 1.3305 0.2045  0.2467  0.1699  322 SER A OG  
599  N N   . SER A 108 ? 0.9299 2.1659 1.4903 0.3418  0.1642  0.2224  323 SER A N   
600  C CA  . SER A 108 ? 0.9774 2.1533 1.4835 0.3975  0.1585  0.2436  323 SER A CA  
601  C C   . SER A 108 ? 0.9181 2.1925 1.4446 0.3973  0.1119  0.2518  323 SER A C   
602  O O   . SER A 108 ? 0.8783 2.2718 1.4634 0.3925  0.0996  0.2598  323 SER A O   
603  C CB  . SER A 108 ? 0.9855 2.1111 1.4722 0.4617  0.2029  0.2721  323 SER A CB  
604  O OG  . SER A 108 ? 1.0351 2.0062 1.4428 0.4863  0.2327  0.2716  323 SER A OG  
605  N N   . GLY A 109 ? 0.9287 2.1513 1.4031 0.4032  0.0882  0.2502  324 GLY A N   
606  C CA  . GLY A 109 ? 0.9202 2.2215 1.3980 0.3983  0.0451  0.2541  324 GLY A CA  
607  C C   . GLY A 109 ? 0.9546 2.2100 1.3804 0.4594  0.0501  0.2860  324 GLY A C   
608  O O   . GLY A 109 ? 0.9921 2.2172 1.4099 0.5127  0.0844  0.3149  324 GLY A O   
609  N N   . GLY A 110 ? 0.8536 2.0960 1.2397 0.4513  0.0200  0.2810  325 GLY A N   
610  C CA  . GLY A 110 ? 0.7915 2.0458 1.1714 0.3926  -0.0168 0.2463  325 GLY A CA  
611  C C   . GLY A 110 ? 0.7574 1.9014 1.0651 0.4072  -0.0176 0.2466  325 GLY A C   
612  O O   . GLY A 110 ? 0.7867 1.8219 1.0566 0.4411  0.0157  0.2596  325 GLY A O   
613  N N   . PHE A 111 ? 0.7029 1.8666 0.9871 0.3804  -0.0525 0.2311  326 PHE A N   
614  C CA  . PHE A 111 ? 0.6837 1.7500 0.8997 0.3989  -0.0511 0.2362  326 PHE A CA  
615  C C   . PHE A 111 ? 0.6801 1.6599 0.8762 0.3656  -0.0504 0.2085  326 PHE A C   
616  O O   . PHE A 111 ? 0.6683 1.6832 0.8802 0.3117  -0.0773 0.1757  326 PHE A O   
617  C CB  . PHE A 111 ? 0.7041 1.8238 0.8972 0.3889  -0.0845 0.2332  326 PHE A CB  
618  C CG  . PHE A 111 ? 0.7171 1.7389 0.8411 0.4100  -0.0783 0.2415  326 PHE A CG  
619  C CD1 . PHE A 111 ? 0.7517 1.7232 0.8416 0.4663  -0.0511 0.2779  326 PHE A CD1 
620  C CD2 . PHE A 111 ? 0.7228 1.6965 0.8156 0.3721  -0.0953 0.2128  326 PHE A CD2 
621  C CE1 . PHE A 111 ? 0.7748 1.6528 0.8034 0.4807  -0.0412 0.2849  326 PHE A CE1 
622  C CE2 . PHE A 111 ? 0.7515 1.6355 0.7837 0.3896  -0.0866 0.2210  326 PHE A CE2 
623  C CZ  . PHE A 111 ? 0.7647 1.6013 0.7660 0.4421  -0.0594 0.2569  326 PHE A CZ  
624  N N   . TYR A 112 ? 0.8852 1.4723 0.8207 0.2763  0.0251  0.1408  327 TYR A N   
625  C CA  . TYR A 112 ? 0.9030 1.3572 0.8286 0.2543  0.0270  0.1171  327 TYR A CA  
626  C C   . TYR A 112 ? 0.9008 1.3023 0.8096 0.2535  0.0199  0.1138  327 TYR A C   
627  O O   . TYR A 112 ? 0.9131 1.3076 0.8021 0.2965  0.0187  0.1372  327 TYR A O   
628  C CB  . TYR A 112 ? 0.9257 1.2902 0.8350 0.2928  0.0345  0.1276  327 TYR A CB  
629  C CG  . TYR A 112 ? 0.9270 1.3404 0.8531 0.2949  0.0422  0.1315  327 TYR A CG  
630  C CD1 . TYR A 112 ? 0.9217 1.4389 0.8540 0.3279  0.0443  0.1581  327 TYR A CD1 
631  C CD2 . TYR A 112 ? 0.8970 1.2613 0.8325 0.2651  0.0492  0.1109  327 TYR A CD2 
632  C CE1 . TYR A 112 ? 0.9415 1.5119 0.8904 0.3286  0.0513  0.1628  327 TYR A CE1 
633  C CE2 . TYR A 112 ? 0.8834 1.2924 0.8338 0.2659  0.0575  0.1150  327 TYR A CE2 
634  C CZ  . TYR A 112 ? 0.9066 1.4198 0.8649 0.2955  0.0576  0.1400  327 TYR A CZ  
635  O OH  . TYR A 112 ? 0.9286 1.4966 0.9031 0.2961  0.0658  0.1459  327 TYR A OH  
636  N N   . GLY A 113 ? 0.8849 1.2469 0.7978 0.2068  0.0187  0.0863  328 GLY A N   
637  C CA  . GLY A 113 ? 0.8805 1.2127 0.7809 0.2025  0.0116  0.0835  328 GLY A CA  
638  C C   . GLY A 113 ? 0.8899 1.1295 0.7847 0.1717  0.0147  0.0601  328 GLY A C   
639  O O   . GLY A 113 ? 0.8852 1.0921 0.7859 0.1487  0.0243  0.0442  328 GLY A O   
640  N N   . VAL A 114 ? 0.8730 1.0733 0.7543 0.1750  0.0087  0.0611  329 VAL A N   
641  C CA  . VAL A 114 ? 0.9154 1.0380 0.7892 0.1528  0.0114  0.0445  329 VAL A CA  
642  C C   . VAL A 114 ? 0.9248 1.0746 0.7958 0.1320  0.0060  0.0375  329 VAL A C   
643  O O   . VAL A 114 ? 0.8942 1.0818 0.7603 0.1523  -0.0026 0.0531  329 VAL A O   
644  C CB  . VAL A 114 ? 0.9363 0.9746 0.7921 0.1806  0.0096  0.0550  329 VAL A CB  
645  C CG1 . VAL A 114 ? 0.9531 0.9356 0.8024 0.1608  0.0107  0.0429  329 VAL A CG1 
646  C CG2 . VAL A 114 ? 0.9736 0.9817 0.8284 0.1987  0.0157  0.0594  329 VAL A CG2 
647  N N   . SER A 115 ? 0.9193 1.0463 0.7889 0.0947  0.0140  0.0155  330 SER A N   
648  C CA  . SER A 115 ? 0.9106 1.0546 0.7732 0.0722  0.0113  0.0060  330 SER A CA  
649  C C   . SER A 115 ? 0.9218 0.9821 0.7713 0.0659  0.0186  -0.0017 330 SER A C   
650  O O   . SER A 115 ? 0.9299 0.9415 0.7755 0.0558  0.0336  -0.0116 330 SER A O   
651  C CB  . SER A 115 ? 0.8876 1.0967 0.7529 0.0271  0.0189  -0.0154 330 SER A CB  
652  O OG  . SER A 115 ? 0.8511 1.1669 0.7288 0.0328  0.0084  -0.0049 330 SER A OG  
653  N N   . SER A 116 ? 0.9197 0.9674 0.7611 0.0750  0.0098  0.0057  331 SER A N   
654  C CA  . SER A 116 ? 0.9406 0.9294 0.7697 0.0669  0.0170  -0.0004 331 SER A CA  
655  C C   . SER A 116 ? 0.9369 0.9489 0.7574 0.0505  0.0142  -0.0066 331 SER A C   
656  O O   . SER A 116 ? 0.9222 0.9901 0.7462 0.0553  0.0018  0.0004  331 SER A O   
657  C CB  . SER A 116 ? 0.9496 0.8884 0.7750 0.0935  0.0110  0.0153  331 SER A CB  
658  O OG  . SER A 116 ? 0.9961 0.9466 0.8232 0.1184  0.0005  0.0308  331 SER A OG  
659  N N   . GLN A 117 ? 0.9432 0.9133 0.7494 0.0334  0.0287  -0.0187 332 GLN A N   
660  C CA  . GLN A 117 ? 0.9586 0.9399 0.7519 0.0182  0.0289  -0.0256 332 GLN A CA  
661  C C   . GLN A 117 ? 0.9874 0.9055 0.7665 0.0261  0.0403  -0.0221 332 GLN A C   
662  O O   . GLN A 117 ? 1.0075 0.8791 0.7747 0.0220  0.0618  -0.0290 332 GLN A O   
663  C CB  . GLN A 117 ? 0.9569 0.9693 0.7382 -0.0223 0.0417  -0.0505 332 GLN A CB  
664  C CG  . GLN A 117 ? 0.9994 1.0634 0.7734 -0.0366 0.0322  -0.0553 332 GLN A CG  
665  C CD  . GLN A 117 ? 1.0403 1.1321 0.7943 -0.0862 0.0476  -0.0850 332 GLN A CD  
666  O OE1 . GLN A 117 ? 1.0269 1.1855 0.7897 -0.1077 0.0446  -0.0941 332 GLN A OE1 
667  N NE2 . GLN A 117 ? 1.0489 1.0896 0.7717 -0.1065 0.0665  -0.1008 332 GLN A NE2 
668  N N   . TYR A 118 ? 0.9758 0.8956 0.7550 0.0405  0.0279  -0.0085 333 TYR A N   
669  C CA  . TYR A 118 ? 1.0091 0.8886 0.7761 0.0484  0.0369  -0.0021 333 TYR A CA  
670  C C   . TYR A 118 ? 1.0084 0.9011 0.7612 0.0361  0.0379  -0.0078 333 TYR A C   
671  O O   . TYR A 118 ? 0.9817 0.9203 0.7370 0.0243  0.0272  -0.0137 333 TYR A O   
672  C CB  . TYR A 118 ? 0.9928 0.8649 0.7695 0.0712  0.0225  0.0188  333 TYR A CB  
673  C CG  . TYR A 118 ? 0.9736 0.8375 0.7614 0.0834  0.0173  0.0250  333 TYR A CG  
674  C CD1 . TYR A 118 ? 0.9737 0.8589 0.7697 0.0895  0.0043  0.0287  333 TYR A CD1 
675  C CD2 . TYR A 118 ? 0.9930 0.8303 0.7798 0.0926  0.0270  0.0297  333 TYR A CD2 
676  C CE1 . TYR A 118 ? 0.9855 0.8564 0.7862 0.1021  0.0016  0.0343  333 TYR A CE1 
677  C CE2 . TYR A 118 ? 0.9751 0.8061 0.7694 0.1025  0.0220  0.0343  333 TYR A CE2 
678  C CZ  . TYR A 118 ? 0.9870 0.8300 0.7871 0.1059  0.0097  0.0353  333 TYR A CZ  
679  O OH  . TYR A 118 ? 1.0192 0.8491 0.8214 0.1166  0.0075  0.0392  333 TYR A OH  
680  N N   . GLU A 119 ? 1.0009 0.8594 0.7377 0.0418  0.0517  -0.0038 334 GLU A N   
681  C CA  . GLU A 119 ? 1.0325 0.8971 0.7527 0.0333  0.0547  -0.0077 334 GLU A CA  
682  C C   . GLU A 119 ? 1.0316 0.8766 0.7470 0.0542  0.0584  0.0111  334 GLU A C   
683  O O   . GLU A 119 ? 1.0497 0.8732 0.7671 0.0707  0.0669  0.0223  334 GLU A O   
684  C CB  . GLU A 119 ? 1.0601 0.9005 0.7500 0.0067  0.0806  -0.0325 334 GLU A CB  
685  C CG  . GLU A 119 ? 1.1047 0.8778 0.7683 0.0157  0.1138  -0.0327 334 GLU A CG  
686  C CD  . GLU A 119 ? 1.2095 0.9425 0.8343 -0.0160 0.1452  -0.0605 334 GLU A CD  
687  O OE1 . GLU A 119 ? 1.2188 0.9914 0.8424 -0.0492 0.1359  -0.0805 334 GLU A OE1 
688  O OE2 . GLU A 119 ? 1.2519 0.9162 0.8441 -0.0088 0.1812  -0.0619 334 GLU A OE2 
689  N N   . SER A 120 ? 1.0453 0.9087 0.7557 0.0539  0.0508  0.0161  335 SER A N   
690  C CA  . SER A 120 ? 1.0494 0.9068 0.7546 0.0706  0.0541  0.0343  335 SER A CA  
691  C C   . SER A 120 ? 1.0387 0.9000 0.7236 0.0631  0.0604  0.0284  335 SER A C   
692  O O   . SER A 120 ? 1.0499 0.9264 0.7274 0.0433  0.0576  0.0107  335 SER A O   
693  C CB  . SER A 120 ? 1.0324 0.9161 0.7593 0.0798  0.0307  0.0539  335 SER A CB  
694  O OG  . SER A 120 ? 1.0200 0.9307 0.7525 0.0731  0.0130  0.0535  335 SER A OG  
695  N N   . LEU A 121 ? 1.0272 0.8828 0.7024 0.0789  0.0688  0.0442  336 LEU A N   
696  C CA  . LEU A 121 ? 1.0399 0.9053 0.6991 0.0760  0.0703  0.0438  336 LEU A CA  
697  C C   . LEU A 121 ? 1.0130 0.9200 0.6932 0.0798  0.0444  0.0609  336 LEU A C   
698  O O   . LEU A 121 ? 0.9933 0.9169 0.6645 0.0759  0.0408  0.0598  336 LEU A O   
699  C CB  . LEU A 121 ? 1.0427 0.8767 0.6731 0.0943  0.0992  0.0528  336 LEU A CB  
700  C CG  . LEU A 121 ? 1.0835 0.8574 0.6768 0.0891  0.1343  0.0336  336 LEU A CG  
701  C CD1 . LEU A 121 ? 1.1167 0.8565 0.6850 0.1218  0.1664  0.0529  336 LEU A CD1 
702  C CD2 . LEU A 121 ? 1.1189 0.8762 0.6790 0.0636  0.1451  0.0083  336 LEU A CD2 
703  N N   . GLU A 122 ? 0.9715 0.8912 0.6745 0.0856  0.0290  0.0757  337 GLU A N   
704  C CA  . GLU A 122 ? 0.9634 0.9082 0.6782 0.0855  0.0099  0.0910  337 GLU A CA  
705  C C   . GLU A 122 ? 0.9783 0.9319 0.7020 0.0799  -0.0051 0.0850  337 GLU A C   
706  O O   . GLU A 122 ? 0.9872 0.9341 0.7158 0.0765  -0.0046 0.0729  337 GLU A O   
707  C CB  . GLU A 122 ? 0.9677 0.9180 0.6927 0.0892  0.0058  0.1092  337 GLU A CB  
708  C CG  . GLU A 122 ? 1.0018 0.9639 0.7197 0.1010  0.0208  0.1226  337 GLU A CG  
709  C CD  . GLU A 122 ? 1.1082 1.0596 0.8248 0.1128  0.0364  0.1228  337 GLU A CD  
710  O OE1 . GLU A 122 ? 1.1049 1.0832 0.8222 0.1250  0.0439  0.1413  337 GLU A OE1 
711  O OE2 . GLU A 122 ? 1.0852 1.0080 0.8001 0.1108  0.0419  0.1065  337 GLU A OE2 
712  N N   . HIS A 123 ? 0.9719 0.9423 0.6952 0.0822  -0.0161 0.0959  338 HIS A N   
713  C CA  . HIS A 123 ? 0.9965 0.9775 0.7233 0.0865  -0.0263 0.0977  338 HIS A CA  
714  C C   . HIS A 123 ? 0.9832 0.9371 0.7112 0.0898  -0.0303 0.1116  338 HIS A C   
715  O O   . HIS A 123 ? 0.9838 0.9280 0.7044 0.0880  -0.0309 0.1261  338 HIS A O   
716  C CB  . HIS A 123 ? 0.9734 0.9849 0.6926 0.0925  -0.0312 0.1048  338 HIS A CB  
717  C CG  . HIS A 123 ? 0.9715 1.0017 0.6907 0.1057  -0.0375 0.1120  338 HIS A CG  
718  N ND1 . HIS A 123 ? 0.9757 0.9765 0.6883 0.1183  -0.0376 0.1301  338 HIS A ND1 
719  C CD2 . HIS A 123 ? 0.9744 1.0524 0.6952 0.1095  -0.0411 0.1051  338 HIS A CD2 
720  C CE1 . HIS A 123 ? 1.0144 1.0394 0.7234 0.1367  -0.0390 0.1372  338 HIS A CE1 
721  N NE2 . HIS A 123 ? 0.9899 1.0716 0.7073 0.1318  -0.0430 0.1232  338 HIS A NE2 
722  N N   . MET A 124 ? 1.0035 0.9434 0.7365 0.0920  -0.0312 0.1061  339 MET A N   
723  C CA  . MET A 124 ? 1.0243 0.9299 0.7510 0.0923  -0.0318 0.1151  339 MET A CA  
724  C C   . MET A 124 ? 1.0101 0.9104 0.7322 0.1076  -0.0327 0.1170  339 MET A C   
725  O O   . MET A 124 ? 0.9981 0.9342 0.7282 0.1154  -0.0348 0.1106  339 MET A O   
726  C CB  . MET A 124 ? 1.0227 0.9156 0.7573 0.0828  -0.0291 0.1082  339 MET A CB  
727  C CG  . MET A 124 ? 1.0141 0.9248 0.7539 0.0773  -0.0242 0.1080  339 MET A CG  
728  S SD  . MET A 124 ? 0.9899 0.8993 0.7359 0.0728  -0.0193 0.1084  339 MET A SD  
729  C CE  . MET A 124 ? 0.9804 0.8875 0.7324 0.0834  -0.0069 0.0940  339 MET A CE  
730  N N   . THR A 125 ? 1.0394 0.8973 0.7450 0.1111  -0.0289 0.1259  340 THR A N   
731  C CA  . THR A 125 ? 1.0915 0.9366 0.7922 0.1274  -0.0262 0.1266  340 THR A CA  
732  C C   . THR A 125 ? 1.0879 0.9004 0.7894 0.1148  -0.0249 0.1178  340 THR A C   
733  O O   . THR A 125 ? 1.0905 0.8775 0.7824 0.0959  -0.0233 0.1181  340 THR A O   
734  C CB  . THR A 125 ? 1.1379 0.9491 0.8076 0.1487  -0.0165 0.1458  340 THR A CB  
735  O OG1 . THR A 125 ? 1.2033 0.9477 0.8451 0.1337  -0.0074 0.1491  340 THR A OG1 
736  C CG2 . THR A 125 ? 1.1435 0.9814 0.8075 0.1593  -0.0160 0.1584  340 THR A CG2 
737  N N   . LEU A 126 ? 1.0834 0.9054 0.7966 0.1235  -0.0256 0.1099  341 LEU A N   
738  C CA  . LEU A 126 ? 1.0831 0.8829 0.7999 0.1145  -0.0246 0.1010  341 LEU A CA  
739  C C   . LEU A 126 ? 1.0964 0.8510 0.7890 0.1268  -0.0177 0.1070  341 LEU A C   
740  O O   . LEU A 126 ? 1.1001 0.8549 0.7822 0.1513  -0.0132 0.1170  341 LEU A O   
741  C CB  . LEU A 126 ? 1.0338 0.8668 0.7765 0.1143  -0.0262 0.0876  341 LEU A CB  
742  C CG  . LEU A 126 ? 1.0019 0.8652 0.7592 0.1032  -0.0258 0.0791  341 LEU A CG  
743  C CD1 . LEU A 126 ? 1.0005 0.8802 0.7720 0.1012  -0.0209 0.0649  341 LEU A CD1 
744  C CD2 . LEU A 126 ? 1.0007 0.8547 0.7560 0.0916  -0.0239 0.0820  341 LEU A CD2 
745  N N   . THR A 127 ? 1.1115 0.8304 0.7915 0.1108  -0.0151 0.1020  342 THR A N   
746  C CA  . THR A 127 ? 1.1190 0.7880 0.7725 0.1182  -0.0065 0.1027  342 THR A CA  
747  C C   . THR A 127 ? 1.0698 0.7584 0.7463 0.1136  -0.0114 0.0904  342 THR A C   
748  O O   . THR A 127 ? 1.0688 0.7735 0.7561 0.0930  -0.0156 0.0835  342 THR A O   
749  C CB  . THR A 127 ? 1.1403 0.7486 0.7518 0.0962  0.0031  0.1041  342 THR A CB  
750  O OG1 . THR A 127 ? 1.1948 0.7792 0.7822 0.1039  0.0117  0.1177  342 THR A OG1 
751  C CG2 . THR A 127 ? 1.1565 0.7026 0.7320 0.1012  0.0158  0.1017  342 THR A CG2 
752  N N   . CYS A 128 ? 1.0362 0.7337 0.7221 0.1352  -0.0100 0.0900  343 CYS A N   
753  C CA  . CYS A 128 ? 1.0426 0.7558 0.7490 0.1338  -0.0120 0.0796  343 CYS A CA  
754  C C   . CYS A 128 ? 1.0442 0.7098 0.7237 0.1415  -0.0046 0.0800  343 CYS A C   
755  O O   . CYS A 128 ? 1.0598 0.7017 0.7190 0.1649  0.0033  0.0895  343 CYS A O   
756  C CB  . CYS A 128 ? 1.0021 0.7640 0.7389 0.1458  -0.0143 0.0763  343 CYS A CB  
757  S SG  . CYS A 128 ? 1.0761 0.8873 0.8332 0.1355  -0.0190 0.0733  343 CYS A SG  
758  N N   . SER A 129 ? 1.0432 0.6967 0.7181 0.1241  -0.0051 0.0713  344 SER A N   
759  C CA  . SER A 129 ? 1.0784 0.6860 0.7245 0.1274  0.0026  0.0683  344 SER A CA  
760  C C   . SER A 129 ? 1.0540 0.6908 0.7270 0.1350  -0.0002 0.0617  344 SER A C   
761  O O   . SER A 129 ? 1.0258 0.7011 0.7239 0.1237  -0.0054 0.0569  344 SER A O   
762  C CB  . SER A 129 ? 1.1078 0.6768 0.7172 0.0954  0.0063  0.0619  344 SER A CB  
763  O OG  . SER A 129 ? 1.1767 0.7288 0.7714 0.0879  0.0092  0.0524  344 SER A OG  
764  N N   . SER A 130 ? 1.0757 0.6953 0.7417 0.1582  0.0059  0.0644  345 SER A N   
765  C CA  . SER A 130 ? 1.0648 0.7057 0.7521 0.1670  0.0057  0.0593  345 SER A CA  
766  C C   . SER A 130 ? 1.1172 0.7085 0.7683 0.1667  0.0130  0.0554  345 SER A C   
767  O O   . SER A 130 ? 1.1438 0.6855 0.7588 0.1821  0.0234  0.0614  345 SER A O   
768  C CB  . SER A 130 ? 1.0540 0.7268 0.7645 0.1917  0.0072  0.0652  345 SER A CB  
769  O OG  . SER A 130 ? 1.0506 0.7695 0.7895 0.1855  0.0020  0.0648  345 SER A OG  
770  N N   . LYS A 131 ? 1.0967 0.7006 0.7525 0.1514  0.0101  0.0467  346 LYS A N   
771  C CA  . LYS A 131 ? 1.1491 0.7138 0.7701 0.1463  0.0163  0.0397  346 LYS A CA  
772  C C   . LYS A 131 ? 1.1389 0.7328 0.7863 0.1644  0.0164  0.0390  346 LYS A C   
773  O O   . LYS A 131 ? 1.1069 0.7490 0.7853 0.1598  0.0118  0.0377  346 LYS A O   
774  C CB  . LYS A 131 ? 1.1642 0.7308 0.7637 0.1084  0.0129  0.0298  346 LYS A CB  
775  C CG  . LYS A 131 ? 1.2221 0.7556 0.7910 0.0847  0.0153  0.0295  346 LYS A CG  
776  C CD  . LYS A 131 ? 1.2777 0.8293 0.8270 0.0401  0.0115  0.0189  346 LYS A CD  
777  C CE  . LYS A 131 ? 1.3412 0.8821 0.8773 0.0172  0.0116  0.0218  346 LYS A CE  
778  N NZ  . LYS A 131 ? 1.3950 0.9903 0.9317 -0.0247 0.0038  0.0164  346 LYS A NZ  
779  N N   . VAL A 132 ? 1.1361 0.6998 0.7687 0.1884  0.0246  0.0423  347 VAL A N   
780  C CA  . VAL A 132 ? 1.1456 0.7296 0.7965 0.2047  0.0267  0.0415  347 VAL A CA  
781  C C   . VAL A 132 ? 1.2057 0.7587 0.8202 0.1922  0.0304  0.0317  347 VAL A C   
782  O O   . VAL A 132 ? 1.2213 0.7110 0.7842 0.1870  0.0393  0.0276  347 VAL A O   
783  C CB  . VAL A 132 ? 1.1432 0.7237 0.7991 0.2379  0.0338  0.0519  347 VAL A CB  
784  C CG1 . VAL A 132 ? 1.1457 0.7468 0.8198 0.2520  0.0369  0.0509  347 VAL A CG1 
785  C CG2 . VAL A 132 ? 1.0948 0.7188 0.7844 0.2437  0.0294  0.0593  347 VAL A CG2 
786  N N   . CYS A 133 ? 1.1778 0.7729 0.8137 0.1883  0.0268  0.0281  348 CYS A N   
787  C CA  . CYS A 133 ? 1.2325 0.8195 0.8388 0.1737  0.0282  0.0181  348 CYS A CA  
788  C C   . CYS A 133 ? 1.2270 0.8274 0.8477 0.1996  0.0331  0.0210  348 CYS A C   
789  O O   . CYS A 133 ? 1.1284 0.7712 0.7922 0.2172  0.0334  0.0291  348 CYS A O   
790  C CB  . CYS A 133 ? 1.2551 0.8967 0.8701 0.1457  0.0198  0.0142  348 CYS A CB  
791  S SG  . CYS A 133 ? 1.3255 0.9477 0.9080 0.1047  0.0156  0.0069  348 CYS A SG  
792  N N   . SER A 134 ? 1.2831 0.8407 0.8620 0.2000  0.0399  0.0134  349 SER A N   
793  C CA  . SER A 134 ? 1.2824 0.8482 0.8673 0.2235  0.0454  0.0154  349 SER A CA  
794  C C   . SER A 134 ? 1.3107 0.8751 0.8574 0.1992  0.0451  0.0013  349 SER A C   
795  O O   . SER A 134 ? 1.3588 0.8646 0.8488 0.1764  0.0507  -0.0115 349 SER A O   
796  C CB  . SER A 134 ? 1.2986 0.8138 0.8662 0.2544  0.0566  0.0222  349 SER A CB  
797  O OG  . SER A 134 ? 1.2975 0.8169 0.8649 0.2753  0.0626  0.0235  349 SER A OG  
798  N N   . PHE A 135 ? 1.2659 0.8950 0.8387 0.2020  0.0411  0.0037  350 PHE A N   
799  C CA  . PHE A 135 ? 1.2664 0.9259 0.8105 0.1748  0.0377  -0.0083 350 PHE A CA  
800  C C   . PHE A 135 ? 1.3415 1.0002 0.8549 0.1278  0.0313  -0.0207 350 PHE A C   
801  O O   . PHE A 135 ? 1.3825 0.9870 0.8371 0.0963  0.0363  -0.0384 350 PHE A O   
802  C CB  . PHE A 135 ? 1.2650 0.8757 0.7634 0.1789  0.0467  -0.0191 350 PHE A CB  
803  C CG  . PHE A 135 ? 1.2448 0.8494 0.7693 0.2245  0.0543  -0.0065 350 PHE A CG  
804  C CD1 . PHE A 135 ? 1.2544 0.8050 0.7803 0.2511  0.0622  0.0016  350 PHE A CD1 
805  C CD2 . PHE A 135 ? 1.1861 0.8487 0.7344 0.2419  0.0547  -0.0002 350 PHE A CD2 
806  C CE1 . PHE A 135 ? 1.2128 0.7701 0.7643 0.2895  0.0692  0.0138  350 PHE A CE1 
807  C CE2 . PHE A 135 ? 1.1703 0.8277 0.7414 0.2808  0.0634  0.0113  350 PHE A CE2 
808  C CZ  . PHE A 135 ? 1.1978 0.8048 0.7719 0.3023  0.0700  0.0176  350 PHE A CZ  
809  N N   . GLY A 136 ? 1.4287 1.1439 0.9791 0.1225  0.0232  -0.0110 351 GLY A N   
810  C CA  . GLY A 136 ? 1.4716 1.2040 1.0012 0.0785  0.0163  -0.0196 351 GLY A CA  
811  C C   . GLY A 136 ? 1.5713 1.2130 1.0572 0.0555  0.0219  -0.0307 351 GLY A C   
812  O O   . GLY A 136 ? 1.6081 1.2592 1.0925 0.0291  0.0173  -0.0314 351 GLY A O   
813  N N   . LYS A 137 ? 1.4419 0.9944 0.8888 0.0685  0.0348  -0.0368 352 LYS A N   
814  C CA  . LYS A 137 ? 1.4617 0.9157 0.8555 0.0543  0.0476  -0.0439 352 LYS A CA  
815  C C   . LYS A 137 ? 1.4033 0.8365 0.8296 0.0906  0.0488  -0.0256 352 LYS A C   
816  O O   . LYS A 137 ? 1.3456 0.8022 0.8150 0.1323  0.0470  -0.0116 352 LYS A O   
817  C CB  . LYS A 137 ? 1.5000 0.8626 0.8271 0.0570  0.0666  -0.0560 352 LYS A CB  
818  C CG  . LYS A 137 ? 1.4732 0.8382 0.8248 0.1085  0.0700  -0.0443 352 LYS A CG  
819  C CD  . LYS A 137 ? 1.5359 0.7874 0.8212 0.1286  0.0946  -0.0464 352 LYS A CD  
820  C CE  . LYS A 137 ? 1.4952 0.7565 0.8166 0.1882  0.0978  -0.0266 352 LYS A CE  
821  N NZ  . LYS A 137 ? 1.4170 0.7666 0.7941 0.2002  0.0836  -0.0234 352 LYS A NZ  
822  N N   . GLN A 138 ? 1.4459 0.8387 0.8487 0.0714  0.0529  -0.0264 353 GLN A N   
823  C CA  . GLN A 138 ? 1.3832 0.7607 0.8095 0.1013  0.0544  -0.0096 353 GLN A CA  
824  C C   . GLN A 138 ? 1.3915 0.6896 0.7814 0.1391  0.0739  -0.0017 353 GLN A C   
825  O O   . GLN A 138 ? 1.4390 0.6453 0.7572 0.1277  0.0941  -0.0090 353 GLN A O   
826  C CB  . GLN A 138 ? 1.3725 0.7295 0.7778 0.0686  0.0551  -0.0124 353 GLN A CB  
827  C CG  . GLN A 138 ? 1.3344 0.6949 0.7693 0.0956  0.0536  0.0052  353 GLN A CG  
828  C CD  . GLN A 138 ? 1.3807 0.6933 0.7771 0.0682  0.0615  0.0037  353 GLN A CD  
829  O OE1 . GLN A 138 ? 1.3693 0.7310 0.7878 0.0392  0.0492  0.0014  353 GLN A OE1 
830  N NE2 . GLN A 138 ? 1.4065 0.6195 0.7406 0.0802  0.0855  0.0070  353 GLN A NE2 
831  N N   . VAL A 139 ? 1.3614 0.6928 0.7948 0.1838  0.0713  0.0142  354 VAL A N   
832  C CA  . VAL A 139 ? 1.4071 0.6815 0.8105 0.2265  0.0900  0.0277  354 VAL A CA  
833  C C   . VAL A 139 ? 1.3856 0.6581 0.7975 0.2507  0.0940  0.0463  354 VAL A C   
834  O O   . VAL A 139 ? 1.3624 0.5777 0.7328 0.2855  0.1149  0.0606  354 VAL A O   
835  C CB  . VAL A 139 ? 1.3786 0.6950 0.8171 0.2615  0.0878  0.0355  354 VAL A CB  
836  C CG1 . VAL A 139 ? 1.4090 0.7084 0.8214 0.2463  0.0904  0.0198  354 VAL A CG1 
837  C CG2 . VAL A 139 ? 1.2992 0.7127 0.8167 0.2652  0.0688  0.0415  354 VAL A CG2 
838  N N   . VAL A 140 ? 1.3354 0.6706 0.7966 0.2370  0.0769  0.0485  355 VAL A N   
839  C CA  . VAL A 140 ? 1.3014 0.6489 0.7744 0.2584  0.0785  0.0656  355 VAL A CA  
840  C C   . VAL A 140 ? 1.2824 0.6527 0.7721 0.2236  0.0660  0.0593  355 VAL A C   
841  O O   . VAL A 140 ? 1.2283 0.6553 0.7586 0.1988  0.0494  0.0494  355 VAL A O   
842  C CB  . VAL A 140 ? 1.2481 0.6769 0.7800 0.2900  0.0696  0.0792  355 VAL A CB  
843  C CG1 . VAL A 140 ? 1.2541 0.7020 0.7902 0.3129  0.0728  0.0976  355 VAL A CG1 
844  C CG2 . VAL A 140 ? 1.3011 0.7218 0.8234 0.3229  0.0803  0.0860  355 VAL A CG2 
845  N N   . GLU A 141 ? 1.2994 0.6264 0.7562 0.2260  0.0766  0.0678  356 GLU A N   
846  C CA  . GLU A 141 ? 1.2757 0.6373 0.7569 0.2033  0.0645  0.0675  356 GLU A CA  
847  C C   . GLU A 141 ? 1.2665 0.6451 0.7565 0.2375  0.0688  0.0881  356 GLU A C   
848  O O   . GLU A 141 ? 1.2811 0.6029 0.7246 0.2687  0.0902  0.1030  356 GLU A O   
849  C CB  . GLU A 141 ? 1.3126 0.6151 0.7456 0.1620  0.0718  0.0562  356 GLU A CB  
850  C CG  . GLU A 141 ? 1.3089 0.6694 0.7816 0.1417  0.0554  0.0572  356 GLU A CG  
851  C CD  . GLU A 141 ? 1.3509 0.6730 0.7856 0.0978  0.0601  0.0481  356 GLU A CD  
852  O OE1 . GLU A 141 ? 1.4221 0.6542 0.7886 0.0847  0.0817  0.0428  356 GLU A OE1 
853  O OE2 . GLU A 141 ? 1.3192 0.6990 0.7888 0.0763  0.0449  0.0467  356 GLU A OE2 
854  N N   . LYS A 142 ? 1.2010 0.6576 0.7455 0.2327  0.0511  0.0897  357 LYS A N   
855  C CA  . LYS A 142 ? 1.2172 0.7101 0.7752 0.2581  0.0514  0.1070  357 LYS A CA  
856  C C   . LYS A 142 ? 1.2097 0.7216 0.7817 0.2306  0.0411  0.1030  357 LYS A C   
857  O O   . LYS A 142 ? 1.1374 0.6940 0.7473 0.2038  0.0256  0.0902  357 LYS A O   
858  C CB  . LYS A 142 ? 1.1585 0.7374 0.7677 0.2779  0.0415  0.1116  357 LYS A CB  
859  C CG  . LYS A 142 ? 1.1975 0.8149 0.8056 0.3154  0.0479  0.1342  357 LYS A CG  
860  C CD  . LYS A 142 ? 1.1880 0.8942 0.8382 0.3323  0.0413  0.1388  357 LYS A CD  
861  C CE  . LYS A 142 ? 1.1724 0.9572 0.8367 0.3548  0.0399  0.1572  357 LYS A CE  
862  N NZ  . LYS A 142 ? 1.1418 1.0101 0.8568 0.3218  0.0219  0.1417  357 LYS A NZ  
863  N N   . VAL A 143 ? 1.2002 0.6741 0.7375 0.2399  0.0528  0.1158  358 VAL A N   
864  C CA  . VAL A 143 ? 1.2356 0.7246 0.7818 0.2174  0.0452  0.1149  358 VAL A CA  
865  C C   . VAL A 143 ? 1.2055 0.7521 0.7726 0.2467  0.0427  0.1320  358 VAL A C   
866  O O   . VAL A 143 ? 1.1916 0.7205 0.7296 0.2858  0.0590  0.1525  358 VAL A O   
867  C CB  . VAL A 143 ? 1.2664 0.6668 0.7531 0.1983  0.0622  0.1151  358 VAL A CB  
868  C CG1 . VAL A 143 ? 1.2388 0.6678 0.7424 0.1727  0.0519  0.1141  358 VAL A CG1 
869  C CG2 . VAL A 143 ? 1.3088 0.6602 0.7689 0.1652  0.0659  0.0966  358 VAL A CG2 
870  N N   . GLU A 144 ? 1.1268 0.7435 0.7395 0.2293  0.0248  0.1248  359 GLU A N   
871  C CA  . GLU A 144 ? 1.1285 0.8117 0.7620 0.2482  0.0201  0.1367  359 GLU A CA  
872  C C   . GLU A 144 ? 1.1280 0.8239 0.7700 0.2248  0.0122  0.1332  359 GLU A C   
873  O O   . GLU A 144 ? 1.1061 0.7922 0.7589 0.1921  0.0046  0.1184  359 GLU A O   
874  C CB  . GLU A 144 ? 1.0759 0.8421 0.7553 0.2490  0.0084  0.1290  359 GLU A CB  
875  C CG  . GLU A 144 ? 1.1201 0.9074 0.7944 0.2847  0.0167  0.1427  359 GLU A CG  
876  C CD  . GLU A 144 ? 1.1741 0.9878 0.8775 0.2737  0.0109  0.1280  359 GLU A CD  
877  O OE1 . GLU A 144 ? 1.1603 0.9559 0.8788 0.2429  0.0044  0.1089  359 GLU A OE1 
878  O OE2 . GLU A 144 ? 1.2023 1.0584 0.9118 0.2990  0.0148  0.1383  359 GLU A OE2 
879  N N   . THR A 145 ? 1.1112 0.8375 0.7489 0.2445  0.0145  0.1489  360 THR A N   
880  C CA  . THR A 145 ? 1.1458 0.8913 0.7922 0.2263  0.0072  0.1472  360 THR A CA  
881  C C   . THR A 145 ? 1.0943 0.9342 0.7758 0.2296  -0.0047 0.1457  360 THR A C   
882  O O   . THR A 145 ? 1.0839 0.9755 0.7684 0.2578  -0.0024 0.1583  360 THR A O   
883  C CB  . THR A 145 ? 1.1685 0.8563 0.7695 0.2413  0.0236  0.1665  360 THR A CB  
884  O OG1 . THR A 145 ? 1.1722 0.7680 0.7348 0.2248  0.0363  0.1617  360 THR A OG1 
885  C CG2 . THR A 145 ? 1.1679 0.8792 0.7795 0.2230  0.0157  0.1655  360 THR A CG2 
886  N N   . GLU A 146 ? 1.0665 0.9331 0.7709 0.2005  -0.0155 0.1309  361 GLU A N   
887  C CA  . GLU A 146 ? 1.0365 0.9843 0.7667 0.1946  -0.0242 0.1238  361 GLU A CA  
888  C C   . GLU A 146 ? 1.0269 0.9814 0.7575 0.1784  -0.0285 0.1212  361 GLU A C   
889  O O   . GLU A 146 ? 1.0241 0.9416 0.7554 0.1571  -0.0293 0.1125  361 GLU A O   
890  C CB  . GLU A 146 ? 1.0049 0.9798 0.7619 0.1727  -0.0286 0.1018  361 GLU A CB  
891  C CG  . GLU A 146 ? 0.9914 1.0389 0.7661 0.1543  -0.0335 0.0881  361 GLU A CG  
892  C CD  . GLU A 146 ? 0.9919 1.1203 0.7681 0.1735  -0.0361 0.1005  361 GLU A CD  
893  O OE1 . GLU A 146 ? 1.0501 1.1734 0.8114 0.2097  -0.0316 0.1246  361 GLU A OE1 
894  O OE2 . GLU A 146 ? 0.9865 1.1832 0.7729 0.1530  -0.0404 0.0878  361 GLU A OE2 
895  N N   . ARG A 147 ? 1.0703 1.0811 0.8006 0.1900  -0.0308 0.1302  362 ARG A N   
896  C CA  . ARG A 147 ? 1.0681 1.0886 0.7961 0.1787  -0.0340 0.1300  362 ARG A CA  
897  C C   . ARG A 147 ? 1.0502 1.1162 0.7977 0.1496  -0.0402 0.1064  362 ARG A C   
898  O O   . ARG A 147 ? 1.0595 1.1737 0.8199 0.1406  -0.0420 0.0934  362 ARG A O   
899  C CB  . ARG A 147 ? 1.0503 1.1082 0.7633 0.2079  -0.0311 0.1530  362 ARG A CB  
900  C CG  . ARG A 147 ? 1.1489 1.2010 0.8538 0.2007  -0.0320 0.1574  362 ARG A CG  
901  C CD  . ARG A 147 ? 1.1811 1.2428 0.8617 0.2373  -0.0231 0.1870  362 ARG A CD  
902  N NE  . ARG A 147 ? 1.2315 1.2708 0.9005 0.2308  -0.0213 0.1936  362 ARG A NE  
903  C CZ  . ARG A 147 ? 1.3072 1.2659 0.9571 0.2215  -0.0128 0.1989  362 ARG A CZ  
904  N NH1 . ARG A 147 ? 1.3287 1.2189 0.9658 0.2157  -0.0053 0.1967  362 ARG A NH1 
905  N NH2 . ARG A 147 ? 1.3121 1.2626 0.9535 0.2147  -0.0113 0.2057  362 ARG A NH2 
906  N N   . ALA A 148 ? 1.0750 1.1229 0.8201 0.1333  -0.0404 0.1008  363 ALA A N   
907  C CA  . ALA A 148 ? 1.0608 1.1365 0.8128 0.1077  -0.0401 0.0788  363 ALA A CA  
908  C C   . ALA A 148 ? 1.0231 1.1785 0.7759 0.1058  -0.0445 0.0748  363 ALA A C   
909  O O   . ALA A 148 ? 1.0313 1.2230 0.7785 0.1286  -0.0484 0.0940  363 ALA A O   
910  C CB  . ALA A 148 ? 1.0389 1.0852 0.7836 0.0980  -0.0372 0.0784  363 ALA A CB  
911  N N   . GLN A 149 ? 0.9747 1.1593 0.7308 0.0778  -0.0414 0.0500  364 GLN A N   
912  C CA  . GLN A 149 ? 0.9597 1.2276 0.7129 0.0617  -0.0447 0.0385  364 GLN A CA  
913  C C   . GLN A 149 ? 1.0094 1.2566 0.7471 0.0269  -0.0350 0.0123  364 GLN A C   
914  O O   . GLN A 149 ? 0.9809 1.1691 0.7133 0.0101  -0.0223 -0.0035 364 GLN A O   
915  C CB  . GLN A 149 ? 0.9515 1.2802 0.7157 0.0524  -0.0462 0.0299  364 GLN A CB  
916  C CG  . GLN A 149 ? 0.9502 1.3762 0.7098 0.0214  -0.0483 0.0109  364 GLN A CG  
917  C CD  . GLN A 149 ? 0.9704 1.4852 0.7299 0.0471  -0.0592 0.0333  364 GLN A CD  
918  O OE1 . GLN A 149 ? 0.9463 1.5251 0.6956 0.0249  -0.0617 0.0208  364 GLN A OE1 
919  N NE2 . GLN A 149 ? 0.9458 1.4617 0.7117 0.0956  -0.0627 0.0673  364 GLN A NE2 
920  N N   . LEU A 150 ? 0.9902 1.2812 0.7161 0.0197  -0.0379 0.0095  365 LEU A N   
921  C CA  . LEU A 150 ? 1.0275 1.2914 0.7299 -0.0111 -0.0251 -0.0147 365 LEU A CA  
922  C C   . LEU A 150 ? 1.0293 1.3363 0.7184 -0.0552 -0.0171 -0.0474 365 LEU A C   
923  O O   . LEU A 150 ? 1.0379 1.4415 0.7336 -0.0635 -0.0280 -0.0490 365 LEU A O   
924  C CB  . LEU A 150 ? 1.0177 1.3054 0.7095 -0.0012 -0.0304 -0.0046 365 LEU A CB  
925  C CG  . LEU A 150 ? 1.0644 1.3315 0.7251 -0.0318 -0.0159 -0.0298 365 LEU A CG  
926  C CD1 . LEU A 150 ? 1.0447 1.2203 0.6950 -0.0200 -0.0021 -0.0236 365 LEU A CD1 
927  C CD2 . LEU A 150 ? 1.0470 1.3875 0.6975 -0.0331 -0.0249 -0.0277 365 LEU A CD2 
928  N N   . GLU A 151 ? 1.0200 1.2570 0.6874 -0.0831 0.0046  -0.0718 366 GLU A N   
929  C CA  . GLU A 151 ? 1.0548 1.3125 0.7016 -0.1329 0.0187  -0.1064 366 GLU A CA  
930  C C   . GLU A 151 ? 1.1298 1.2848 0.7351 -0.1562 0.0507  -0.1294 366 GLU A C   
931  O O   . GLU A 151 ? 1.1665 1.2401 0.7723 -0.1382 0.0645  -0.1217 366 GLU A O   
932  C CB  . GLU A 151 ? 1.0439 1.3218 0.7141 -0.1343 0.0152  -0.1054 366 GLU A CB  
933  C CG  . GLU A 151 ? 1.1056 1.3904 0.7528 -0.1905 0.0344  -0.1419 366 GLU A CG  
934  C CD  . GLU A 151 ? 1.1216 1.4165 0.7934 -0.1874 0.0327  -0.1378 366 GLU A CD  
935  O OE1 . GLU A 151 ? 1.0545 1.4454 0.7565 -0.1732 0.0116  -0.1222 366 GLU A OE1 
936  O OE2 . GLU A 151 ? 1.1738 1.3795 0.8317 -0.1962 0.0553  -0.1485 366 GLU A OE2 
937  N N   . ASP A 152 ? 1.1663 1.3242 0.7313 -0.1937 0.0652  -0.1561 367 ASP A N   
938  C CA  . ASP A 152 ? 1.2359 1.2918 0.7472 -0.2236 0.1046  -0.1837 367 ASP A CA  
939  C C   . ASP A 152 ? 1.2498 1.2150 0.7478 -0.1830 0.1191  -0.1636 367 ASP A C   
940  O O   . ASP A 152 ? 1.3241 1.1946 0.7975 -0.1758 0.1491  -0.1653 367 ASP A O   
941  C CB  . ASP A 152 ? 1.3225 1.3352 0.8289 -0.2443 0.1237  -0.1981 367 ASP A CB  
942  C CG  . ASP A 152 ? 1.3982 1.4462 0.8718 -0.3138 0.1384  -0.2395 367 ASP A CG  
943  O OD1 . ASP A 152 ? 1.4223 1.5779 0.9009 -0.3412 0.1188  -0.2503 367 ASP A OD1 
944  O OD2 . ASP A 152 ? 1.4810 1.4513 0.9204 -0.3430 0.1719  -0.2611 367 ASP A OD2 
945  N N   . GLY A 153 ? 1.2237 1.2237 0.7382 -0.1536 0.0991  -0.1415 368 GLY A N   
946  C CA  . GLY A 153 ? 1.2252 1.1620 0.7371 -0.1123 0.1075  -0.1165 368 GLY A CA  
947  C C   . GLY A 153 ? 1.2048 1.1084 0.7488 -0.0752 0.1036  -0.0898 368 GLY A C   
948  O O   . GLY A 153 ? 1.2274 1.0608 0.7532 -0.0540 0.1269  -0.0799 368 GLY A O   
949  N N   . ARG A 154 ? 1.1359 1.0914 0.7240 -0.0650 0.0767  -0.0766 369 ARG A N   
950  C CA  . ARG A 154 ? 1.1363 1.0678 0.7539 -0.0331 0.0701  -0.0524 369 ARG A CA  
951  C C   . ARG A 154 ? 1.0902 1.0851 0.7475 -0.0241 0.0401  -0.0396 369 ARG A C   
952  O O   . ARG A 154 ? 1.0768 1.1352 0.7388 -0.0413 0.0283  -0.0497 369 ARG A O   
953  C CB  . ARG A 154 ? 1.1671 1.0344 0.7684 -0.0391 0.0969  -0.0634 369 ARG A CB  
954  C CG  . ARG A 154 ? 1.2007 1.0827 0.7901 -0.0794 0.1046  -0.0931 369 ARG A CG  
955  C CD  . ARG A 154 ? 1.2859 1.0892 0.8433 -0.0919 0.1409  -0.1086 369 ARG A CD  
956  N NE  . ARG A 154 ? 1.2955 1.1230 0.8735 -0.1079 0.1347  -0.1172 369 ARG A NE  
957  C CZ  . ARG A 154 ? 1.3498 1.1193 0.9056 -0.1225 0.1637  -0.1311 369 ARG A CZ  
958  N NH1 . ARG A 154 ? 1.4128 1.0896 0.9171 -0.1256 0.2059  -0.1405 369 ARG A NH1 
959  N NH2 . ARG A 154 ? 1.3385 1.1398 0.9210 -0.1308 0.1533  -0.1334 369 ARG A NH2 
960  N N   . PHE A 155 ? 1.0415 1.0209 0.7231 0.0036  0.0303  -0.0167 370 PHE A N   
961  C CA  . PHE A 155 ? 1.0682 1.0875 0.7783 0.0171  0.0083  -0.0024 370 PHE A CA  
962  C C   . PHE A 155 ? 1.0345 1.0395 0.7546 0.0128  0.0129  -0.0098 370 PHE A C   
963  O O   . PHE A 155 ? 1.0347 0.9875 0.7501 0.0165  0.0275  -0.0106 370 PHE A O   
964  C CB  . PHE A 155 ? 1.0510 1.0577 0.7734 0.0440  -0.0033 0.0249  370 PHE A CB  
965  C CG  . PHE A 155 ? 1.0083 1.0329 0.7219 0.0485  -0.0078 0.0338  370 PHE A CG  
966  C CD1 . PHE A 155 ? 1.0007 1.0791 0.7163 0.0513  -0.0202 0.0384  370 PHE A CD1 
967  C CD2 . PHE A 155 ? 1.0275 1.0217 0.7292 0.0521  0.0026  0.0390  370 PHE A CD2 
968  C CE1 . PHE A 155 ? 1.0174 1.1135 0.7236 0.0563  -0.0231 0.0469  370 PHE A CE1 
969  C CE2 . PHE A 155 ? 1.0103 1.0228 0.7033 0.0562  -0.0008 0.0474  370 PHE A CE2 
970  C CZ  . PHE A 155 ? 0.9854 1.0458 0.6809 0.0573  -0.0139 0.0505  370 PHE A CZ  
971  N N   . VAL A 156 ? 1.0080 1.0658 0.7404 0.0066  0.0024  -0.0139 371 VAL A N   
972  C CA  . VAL A 156 ? 1.0255 1.0799 0.7688 0.0024  0.0057  -0.0201 371 VAL A CA  
973  C C   . VAL A 156 ? 1.0072 1.0850 0.7717 0.0316  -0.0118 0.0028  371 VAL A C   
974  O O   . VAL A 156 ? 0.9899 1.1113 0.7574 0.0465  -0.0244 0.0173  371 VAL A O   
975  C CB  . VAL A 156 ? 1.0260 1.1259 0.7609 -0.0339 0.0129  -0.0459 371 VAL A CB  
976  C CG1 . VAL A 156 ? 1.0845 1.1529 0.7851 -0.0659 0.0340  -0.0703 371 VAL A CG1 
977  C CG2 . VAL A 156 ? 0.9918 1.1886 0.7398 -0.0311 -0.0060 -0.0388 371 VAL A CG2 
978  N N   . TYR A 157 ? 0.9993 1.0420 0.7731 0.0424  -0.0094 0.0075  372 TYR A N   
979  C CA  . TYR A 157 ? 1.0000 1.0458 0.7848 0.0698  -0.0203 0.0275  372 TYR A CA  
980  C C   . TYR A 157 ? 1.0147 1.0836 0.8102 0.0665  -0.0181 0.0206  372 TYR A C   
981  O O   . TYR A 157 ? 0.9847 1.0146 0.7823 0.0599  -0.0085 0.0120  372 TYR A O   
982  C CB  . TYR A 157 ? 1.0088 0.9925 0.7910 0.0842  -0.0198 0.0399  372 TYR A CB  
983  C CG  . TYR A 157 ? 1.0093 0.9755 0.7820 0.0829  -0.0200 0.0459  372 TYR A CG  
984  C CD1 . TYR A 157 ? 1.0169 0.9651 0.7828 0.0694  -0.0087 0.0354  372 TYR A CD1 
985  C CD2 . TYR A 157 ? 1.0291 0.9947 0.7955 0.0968  -0.0281 0.0637  372 TYR A CD2 
986  C CE1 . TYR A 157 ? 1.0100 0.9497 0.7675 0.0709  -0.0081 0.0431  372 TYR A CE1 
987  C CE2 . TYR A 157 ? 1.0174 0.9726 0.7761 0.0935  -0.0280 0.0697  372 TYR A CE2 
988  C CZ  . TYR A 157 ? 1.0151 0.9624 0.7716 0.0810  -0.0194 0.0597  372 TYR A CZ  
989  O OH  . TYR A 157 ? 1.0166 0.9597 0.7657 0.0804  -0.0182 0.0676  372 TYR A OH  
990  N N   . ARG A 158 ? 0.9772 1.1161 0.7789 0.0730  -0.0256 0.0264  373 ARG A N   
991  C CA  . ARG A 158 ? 0.9503 1.1320 0.7633 0.0672  -0.0237 0.0205  373 ARG A CA  
992  C C   . ARG A 158 ? 0.9418 1.1236 0.7592 0.1063  -0.0287 0.0448  373 ARG A C   
993  O O   . ARG A 158 ? 0.9468 1.1576 0.7582 0.1347  -0.0343 0.0662  373 ARG A O   
994  C CB  . ARG A 158 ? 0.9345 1.2138 0.7500 0.0439  -0.0265 0.0096  373 ARG A CB  
995  C CG  . ARG A 158 ? 0.9378 1.2097 0.7397 -0.0026 -0.0159 -0.0203 373 ARG A CG  
996  C CD  . ARG A 158 ? 0.9055 1.2697 0.7085 -0.0398 -0.0142 -0.0392 373 ARG A CD  
997  N NE  . ARG A 158 ? 0.9611 1.3014 0.7398 -0.0893 0.0015  -0.0714 373 ARG A NE  
998  C CZ  . ARG A 158 ? 0.9669 1.3310 0.7294 -0.1050 -0.0003 -0.0797 373 ARG A CZ  
999  N NH1 . ARG A 158 ? 0.9409 1.3626 0.7125 -0.0755 -0.0182 -0.0575 373 ARG A NH1 
1000 N NH2 . ARG A 158 ? 1.0014 1.3247 0.7329 -0.1498 0.0195  -0.1103 373 ARG A NH2 
1001 N N   . LEU A 159 ? 0.9386 1.0832 0.7614 0.1101  -0.0235 0.0426  374 LEU A N   
1002 C CA  . LEU A 159 ? 0.9234 1.0643 0.7458 0.1445  -0.0242 0.0622  374 LEU A CA  
1003 C C   . LEU A 159 ? 0.8930 1.0824 0.7312 0.1330  -0.0205 0.0529  374 LEU A C   
1004 O O   . LEU A 159 ? 0.8995 1.0454 0.7418 0.1269  -0.0140 0.0444  374 LEU A O   
1005 C CB  . LEU A 159 ? 0.9565 1.0032 0.7667 0.1579  -0.0210 0.0678  374 LEU A CB  
1006 C CG  . LEU A 159 ? 0.9876 0.9857 0.7824 0.1579  -0.0231 0.0729  374 LEU A CG  
1007 C CD1 . LEU A 159 ? 0.9784 0.9570 0.7785 0.1285  -0.0211 0.0552  374 LEU A CD1 
1008 C CD2 . LEU A 159 ? 1.0166 0.9447 0.7920 0.1754  -0.0198 0.0843  374 LEU A CD2 
1009 N N   . LEU A 160 ? 0.8673 1.1555 0.7140 0.1290  -0.0241 0.0553  375 LEU A N   
1010 C CA  . LEU A 160 ? 0.8522 1.2074 0.7139 0.1036  -0.0206 0.0417  375 LEU A CA  
1011 C C   . LEU A 160 ? 0.8349 1.2499 0.7040 0.1412  -0.0221 0.0662  375 LEU A C   
1012 O O   . LEU A 160 ? 0.8289 1.2701 0.6891 0.1840  -0.0252 0.0940  375 LEU A O   
1013 C CB  . LEU A 160 ? 0.8361 1.2785 0.6998 0.0632  -0.0229 0.0242  375 LEU A CB  
1014 C CG  . LEU A 160 ? 0.8700 1.2563 0.7200 0.0245  -0.0168 -0.0014 375 LEU A CG  
1015 C CD1 . LEU A 160 ? 0.8492 1.3057 0.6948 -0.0322 -0.0108 -0.0302 375 LEU A CD1 
1016 C CD2 . LEU A 160 ? 0.8781 1.1502 0.7225 0.0217  -0.0046 -0.0108 375 LEU A CD2 
1017 N N   . ARG A 161 ? 0.8371 1.2743 0.7191 0.1274  -0.0165 0.0578  376 ARG A N   
1018 C CA  . ARG A 161 ? 0.8206 1.3290 0.7105 0.1620  -0.0164 0.0814  376 ARG A CA  
1019 C C   . ARG A 161 ? 0.8263 1.2649 0.6973 0.2223  -0.0135 0.1109  376 ARG A C   
1020 O O   . ARG A 161 ? 0.8174 1.3096 0.6814 0.2681  -0.0112 0.1407  376 ARG A O   
1021 C CB  . ARG A 161 ? 0.8014 1.4576 0.7005 0.1590  -0.0230 0.0910  376 ARG A CB  
1022 C CG  . ARG A 161 ? 0.8257 1.5749 0.7308 0.2061  -0.0215 0.1239  376 ARG A CG  
1023 C CD  . ARG A 161 ? 0.8124 1.7377 0.7349 0.1847  -0.0273 0.1257  376 ARG A CD  
1024 N NE  . ARG A 161 ? 0.8472 1.8197 0.7880 0.1277  -0.0244 0.0980  376 ARG A NE  
1025 C CZ  . ARG A 161 ? 0.8477 1.7795 0.7876 0.0589  -0.0209 0.0573  376 ARG A CZ  
1026 N NH1 . ARG A 161 ? 0.8354 1.6891 0.7601 0.0385  -0.0218 0.0393  376 ARG A NH1 
1027 N NH2 . ARG A 161 ? 0.8388 1.8093 0.7891 0.0101  -0.0131 0.0353  376 ARG A NH2 
1028 N N   . SER A 162 ? 0.8631 1.1823 0.7205 0.2230  -0.0107 0.1036  377 SER A N   
1029 C CA  . SER A 162 ? 0.9275 1.1690 0.7584 0.2689  -0.0047 0.1257  377 SER A CA  
1030 C C   . SER A 162 ? 0.9596 1.1930 0.7898 0.2932  0.0032  0.1350  377 SER A C   
1031 O O   . SER A 162 ? 0.9014 1.1128 0.7462 0.2680  0.0041  0.1164  377 SER A O   
1032 C CB  . SER A 162 ? 0.9754 1.1069 0.7918 0.2536  -0.0050 0.1126  377 SER A CB  
1033 O OG  . SER A 162 ? 1.0452 1.1039 0.8277 0.2887  0.0021  0.1314  377 SER A OG  
1034 N N   . PRO A 163 ? 0.9713 1.2176 0.7812 0.3448  0.0119  0.1649  378 PRO A N   
1035 C CA  . PRO A 163 ? 0.9798 1.2108 0.7844 0.3712  0.0214  0.1746  378 PRO A CA  
1036 C C   . PRO A 163 ? 1.0329 1.1509 0.8273 0.3552  0.0237  0.1561  378 PRO A C   
1037 O O   . PRO A 163 ? 1.0617 1.0882 0.8300 0.3531  0.0254  0.1520  378 PRO A O   
1038 C CB  . PRO A 163 ? 0.9890 1.2126 0.7558 0.4356  0.0365  0.2118  378 PRO A CB  
1039 C CG  . PRO A 163 ? 0.9856 1.2484 0.7454 0.4432  0.0338  0.2239  378 PRO A CG  
1040 C CD  . PRO A 163 ? 0.9511 1.2369 0.7409 0.3844  0.0163  0.1935  378 PRO A CD  
1041 N N   . MET A 164 ? 1.0108 1.1451 0.8269 0.3400  0.0239  0.1443  379 MET A N   
1042 C CA  . MET A 164 ? 1.0510 1.0970 0.8558 0.3377  0.0286  0.1340  379 MET A CA  
1043 C C   . MET A 164 ? 1.0922 1.0821 0.8564 0.3865  0.0419  0.1559  379 MET A C   
1044 O O   . MET A 164 ? 1.0756 1.1182 0.8350 0.4248  0.0501  0.1792  379 MET A O   
1045 C CB  . MET A 164 ? 1.0117 1.0977 0.8473 0.3163  0.0292  0.1210  379 MET A CB  
1046 C CG  . MET A 164 ? 1.0600 1.0728 0.8967 0.2936  0.0306  0.1014  379 MET A CG  
1047 S SD  . MET A 164 ? 0.9554 1.0126 0.8223 0.2750  0.0374  0.0910  379 MET A SD  
1048 C CE  . MET A 164 ? 0.9246 0.9955 0.8101 0.2207  0.0366  0.0659  379 MET A CE  
1049 N N   . CYS A 165 ? 1.1070 0.9918 0.8378 0.3847  0.0464  0.1489  380 CYS A N   
1050 C CA  . CYS A 165 ? 1.2001 1.0105 0.8794 0.4249  0.0640  0.1654  380 CYS A CA  
1051 C C   . CYS A 165 ? 1.2367 1.0652 0.9194 0.4494  0.0720  0.1729  380 CYS A C   
1052 O O   . CYS A 165 ? 1.1790 1.0430 0.8983 0.4258  0.0636  0.1581  380 CYS A O   
1053 C CB  . CYS A 165 ? 1.2667 0.9671 0.9093 0.4038  0.0670  0.1495  380 CYS A CB  
1054 S SG  . CYS A 165 ? 1.3438 1.0422 1.0220 0.3534  0.0513  0.1189  380 CYS A SG  
1055 N N   . GLU A 166 ? 1.1881 1.2599 1.1421 0.4586  0.0489  0.2469  381 GLU A N   
1056 C CA  . GLU A 166 ? 1.1959 1.2700 1.1629 0.4760  0.0654  0.2425  381 GLU A CA  
1057 C C   . GLU A 166 ? 1.2411 1.2510 1.1935 0.4284  0.0596  0.1927  381 GLU A C   
1058 O O   . GLU A 166 ? 1.1938 1.2554 1.1640 0.4132  0.0464  0.1748  381 GLU A O   
1059 C CB  . GLU A 166 ? 1.3132 1.3189 1.2681 0.5140  0.1128  0.2678  381 GLU A CB  
1060 C CG  . GLU A 166 ? 1.3959 1.3281 1.3408 0.5212  0.1438  0.2491  381 GLU A CG  
1061 C CD  . GLU A 166 ? 1.5123 1.3498 1.4335 0.5458  0.1961  0.2654  381 GLU A CD  
1062 O OE1 . GLU A 166 ? 1.5308 1.3749 1.4501 0.5652  0.2083  0.2981  381 GLU A OE1 
1063 O OE2 . GLU A 166 ? 1.5918 1.3473 1.4934 0.5442  0.2275  0.2446  381 GLU A OE2 
1064 N N   . TYR A 167 ? 1.1736 1.0779 1.0930 0.4021  0.0689  0.1715  382 TYR A N   
1065 C CA  . TYR A 167 ? 1.1420 0.9927 1.0453 0.3589  0.0644  0.1299  382 TYR A CA  
1066 C C   . TYR A 167 ? 1.1019 1.0281 1.0269 0.3227  0.0262  0.1078  382 TYR A C   
1067 O O   . TYR A 167 ? 1.0650 0.9951 0.9930 0.3063  0.0236  0.0874  382 TYR A O   
1068 C CB  . TYR A 167 ? 1.1530 0.9056 1.0210 0.3289  0.0733  0.1124  382 TYR A CB  
1069 C CG  . TYR A 167 ? 1.1610 0.8758 1.0123 0.2819  0.0649  0.0736  382 TYR A CG  
1070 C CD1 . TYR A 167 ? 1.1965 0.8434 1.0213 0.2775  0.0940  0.0570  382 TYR A CD1 
1071 C CD2 . TYR A 167 ? 1.1194 0.8705 0.9810 0.2432  0.0304  0.0556  382 TYR A CD2 
1072 C CE1 . TYR A 167 ? 1.1859 0.8128 0.9934 0.2328  0.0840  0.0247  382 TYR A CE1 
1073 C CE2 . TYR A 167 ? 1.1221 0.8513 0.9711 0.2051  0.0222  0.0283  382 TYR A CE2 
1074 C CZ  . TYR A 167 ? 1.1590 0.8319 0.9806 0.1987  0.0466  0.0136  382 TYR A CZ  
1075 O OH  . TYR A 167 ? 1.1869 0.8523 0.9943 0.1589  0.0356  -0.0105 382 TYR A OH  
1076 N N   . LEU A 168 ? 1.0904 1.0734 1.0284 0.3094  0.0003  0.1114  383 LEU A N   
1077 C CA  . LEU A 168 ? 1.0563 1.0945 1.0106 0.2732  -0.0278 0.0883  383 LEU A CA  
1078 C C   . LEU A 168 ? 1.0140 1.1390 0.9942 0.2829  -0.0324 0.0926  383 LEU A C   
1079 O O   . LEU A 168 ? 0.9643 1.1047 0.9519 0.2561  -0.0416 0.0703  383 LEU A O   
1080 C CB  . LEU A 168 ? 1.0159 1.0869 0.9735 0.2548  -0.0475 0.0876  383 LEU A CB  
1081 C CG  . LEU A 168 ? 1.0205 1.0284 0.9621 0.2258  -0.0528 0.0709  383 LEU A CG  
1082 C CD1 . LEU A 168 ? 0.9456 0.9979 0.8973 0.1999  -0.0721 0.0598  383 LEU A CD1 
1083 C CD2 . LEU A 168 ? 1.0260 0.9804 0.9589 0.2039  -0.0506 0.0491  383 LEU A CD2 
1084 N N   . VAL A 169 ? 1.0004 1.1895 0.9956 0.3207  -0.0255 0.1238  384 VAL A N   
1085 C CA  . VAL A 169 ? 0.9905 1.2794 1.0141 0.3288  -0.0302 0.1302  384 VAL A CA  
1086 C C   . VAL A 169 ? 0.9587 1.2115 0.9824 0.3328  -0.0132 0.1179  384 VAL A C   
1087 O O   . VAL A 169 ? 0.9133 1.2006 0.9476 0.3041  -0.0237 0.0963  384 VAL A O   
1088 C CB  . VAL A 169 ? 0.9494 1.3219 0.9913 0.3758  -0.0237 0.1742  384 VAL A CB  
1089 C CG1 . VAL A 169 ? 0.8135 1.3191 0.8880 0.3720  -0.0363 0.1786  384 VAL A CG1 
1090 C CG2 . VAL A 169 ? 0.9520 1.3400 0.9837 0.3746  -0.0357 0.1893  384 VAL A CG2 
1091 N N   . ASN A 170 ? 0.9727 1.1493 0.9806 0.3661  0.0171  0.1301  385 ASN A N   
1092 C CA  . ASN A 170 ? 0.9647 1.0956 0.9649 0.3687  0.0385  0.1157  385 ASN A CA  
1093 C C   . ASN A 170 ? 0.9596 1.0501 0.9438 0.3168  0.0229  0.0774  385 ASN A C   
1094 O O   . ASN A 170 ? 0.8992 1.0175 0.8920 0.3028  0.0214  0.0637  385 ASN A O   
1095 C CB  . ASN A 170 ? 1.0611 1.0901 1.0345 0.4018  0.0783  0.1266  385 ASN A CB  
1096 C CG  . ASN A 170 ? 1.1610 1.2141 1.1476 0.4597  0.0994  0.1723  385 ASN A CG  
1097 O OD1 . ASN A 170 ? 1.1954 1.3497 1.2169 0.4934  0.0992  0.2008  385 ASN A OD1 
1098 N ND2 . ASN A 170 ? 1.2341 1.1976 1.1929 0.4717  0.1198  0.1824  385 ASN A ND2 
1099 N N   . PHE A 171 ? 0.9838 1.0131 0.9457 0.2893  0.0123  0.0635  386 PHE A N   
1100 C CA  . PHE A 171 ? 0.9691 0.9691 0.9188 0.2452  -0.0028 0.0353  386 PHE A CA  
1101 C C   . PHE A 171 ? 0.9740 1.0484 0.9486 0.2220  -0.0245 0.0266  386 PHE A C   
1102 O O   . PHE A 171 ? 0.9146 0.9877 0.8877 0.2015  -0.0256 0.0117  386 PHE A O   
1103 C CB  . PHE A 171 ? 0.9601 0.9068 0.8913 0.2240  -0.0125 0.0287  386 PHE A CB  
1104 C CG  . PHE A 171 ? 0.9385 0.8664 0.8620 0.1843  -0.0281 0.0080  386 PHE A CG  
1105 C CD1 . PHE A 171 ? 0.9374 0.8307 0.8414 0.1697  -0.0196 -0.0057 386 PHE A CD1 
1106 C CD2 . PHE A 171 ? 0.8994 0.8472 0.8344 0.1634  -0.0488 0.0045  386 PHE A CD2 
1107 C CE1 . PHE A 171 ? 0.9001 0.7872 0.7984 0.1372  -0.0344 -0.0172 386 PHE A CE1 
1108 C CE2 . PHE A 171 ? 0.8746 0.8084 0.8065 0.1347  -0.0596 -0.0069 386 PHE A CE2 
1109 C CZ  . PHE A 171 ? 0.8948 0.8024 0.8093 0.1227  -0.0538 -0.0152 386 PHE A CZ  
1110 N N   . LEU A 172 ? 0.8987 1.0357 0.8922 0.2211  -0.0394 0.0346  387 LEU A N   
1111 C CA  . LEU A 172 ? 0.9157 1.1188 0.9282 0.1934  -0.0538 0.0222  387 LEU A CA  
1112 C C   . LEU A 172 ? 0.8365 1.0952 0.8657 0.2011  -0.0450 0.0239  387 LEU A C   
1113 O O   . LEU A 172 ? 0.8269 1.1004 0.8609 0.1723  -0.0483 0.0072  387 LEU A O   
1114 C CB  . LEU A 172 ? 0.8691 1.1380 0.8939 0.1886  -0.0672 0.0283  387 LEU A CB  
1115 C CG  . LEU A 172 ? 0.8523 1.0893 0.8665 0.1659  -0.0782 0.0183  387 LEU A CG  
1116 C CD1 . LEU A 172 ? 0.8053 1.1235 0.8289 0.1603  -0.0881 0.0232  387 LEU A CD1 
1117 C CD2 . LEU A 172 ? 0.8186 1.0159 0.8290 0.1298  -0.0813 -0.0054 387 LEU A CD2 
1118 N N   . HIS A 173 ? 0.8035 1.0947 0.8430 0.2416  -0.0309 0.0464  388 HIS A N   
1119 C CA  . HIS A 173 ? 0.7936 1.1514 0.8546 0.2523  -0.0212 0.0510  388 HIS A CA  
1120 C C   . HIS A 173 ? 0.8215 1.1179 0.8663 0.2411  -0.0076 0.0336  388 HIS A C   
1121 O O   . HIS A 173 ? 0.7926 1.1328 0.8498 0.2232  -0.0072 0.0236  388 HIS A O   
1122 C CB  . HIS A 173 ? 0.7857 1.1899 0.8637 0.3067  -0.0046 0.0855  388 HIS A CB  
1123 C CG  . HIS A 173 ? 0.8442 1.2944 0.9420 0.3303  0.0151  0.0941  388 HIS A CG  
1124 N ND1 . HIS A 173 ? 0.9075 1.3022 0.9972 0.3737  0.0480  0.1082  388 HIS A ND1 
1125 C CD2 . HIS A 173 ? 0.8544 1.4012 0.9795 0.3157  0.0104  0.0901  388 HIS A CD2 
1126 C CE1 . HIS A 173 ? 0.8837 1.3401 0.9968 0.3885  0.0624  0.1137  388 HIS A CE1 
1127 N NE2 . HIS A 173 ? 0.8511 1.4044 0.9872 0.3530  0.0384  0.1036  388 HIS A NE2 
1128 N N   . LYS A 174 ? 0.8567 1.0548 0.8709 0.2463  0.0039  0.0284  389 LYS A N   
1129 C CA  . LYS A 174 ? 0.8774 1.0208 0.8693 0.2276  0.0136  0.0098  389 LYS A CA  
1130 C C   . LYS A 174 ? 0.8741 1.0146 0.8624 0.1829  -0.0066 -0.0077 389 LYS A C   
1131 O O   . LYS A 174 ? 0.8416 0.9882 0.8273 0.1651  -0.0029 -0.0175 389 LYS A O   
1132 C CB  . LYS A 174 ? 0.8961 0.9424 0.8516 0.2340  0.0297  0.0051  389 LYS A CB  
1133 C CG  . LYS A 174 ? 0.8976 0.9164 0.8462 0.2756  0.0645  0.0168  389 LYS A CG  
1134 C CD  . LYS A 174 ? 0.9665 0.8992 0.8846 0.2809  0.0767  0.0170  389 LYS A CD  
1135 C CE  . LYS A 174 ? 0.9777 0.8565 0.8804 0.3196  0.1206  0.0257  389 LYS A CE  
1136 N NZ  . LYS A 174 ? 1.0457 0.8319 0.9127 0.3114  0.1326  0.0199  389 LYS A NZ  
1137 N N   . LEU A 175 ? 0.8752 1.0024 0.8624 0.1664  -0.0245 -0.0096 390 LEU A N   
1138 C CA  . LEU A 175 ? 0.8620 0.9705 0.8441 0.1307  -0.0373 -0.0218 390 LEU A CA  
1139 C C   . LEU A 175 ? 0.8012 0.9679 0.8038 0.1100  -0.0394 -0.0284 390 LEU A C   
1140 O O   . LEU A 175 ? 0.8031 0.9536 0.7997 0.0867  -0.0375 -0.0357 390 LEU A O   
1141 C CB  . LEU A 175 ? 0.8808 0.9653 0.8607 0.1234  -0.0507 -0.0206 390 LEU A CB  
1142 C CG  . LEU A 175 ? 0.8396 0.8846 0.8114 0.0984  -0.0599 -0.0258 390 LEU A CG  
1143 C CD1 . LEU A 175 ? 0.8209 0.8192 0.7682 0.0934  -0.0566 -0.0261 390 LEU A CD1 
1144 C CD2 . LEU A 175 ? 0.8148 0.8483 0.7891 0.1004  -0.0689 -0.0224 390 LEU A CD2 
1145 N N   . ARG A 176 ? 0.7765 1.0152 0.8018 0.1162  -0.0416 -0.0246 391 ARG A N   
1146 C CA  . ARG A 176 ? 0.7567 1.0581 0.7996 0.0884  -0.0418 -0.0349 391 ARG A CA  
1147 C C   . ARG A 176 ? 0.7504 1.0647 0.7950 0.0839  -0.0288 -0.0380 391 ARG A C   
1148 O O   . ARG A 176 ? 0.7359 1.0789 0.7879 0.0522  -0.0253 -0.0495 391 ARG A O   
1149 C CB  . ARG A 176 ? 0.7485 1.1445 0.8143 0.0964  -0.0471 -0.0280 391 ARG A CB  
1150 C CG  . ARG A 176 ? 0.7454 1.1779 0.8225 0.1437  -0.0395 -0.0049 391 ARG A CG  
1151 C CD  . ARG A 176 ? 0.7259 1.2776 0.8309 0.1532  -0.0458 0.0091  391 ARG A CD  
1152 N NE  . ARG A 176 ? 0.7308 1.3511 0.8459 0.1046  -0.0539 -0.0109 391 ARG A NE  
1153 C CZ  . ARG A 176 ? 0.7421 1.4785 0.8771 0.0955  -0.0626 -0.0057 391 ARG A CZ  
1154 N NH1 . ARG A 176 ? 0.7408 1.5491 0.8935 0.1389  -0.0653 0.0259  391 ARG A NH1 
1155 N NH2 . ARG A 176 ? 0.7201 1.5032 0.8556 0.0405  -0.0663 -0.0317 391 ARG A NH2 
1156 N N   . GLN A 177 ? 0.7568 1.0460 0.7917 0.1124  -0.0176 -0.0298 392 GLN A N   
1157 C CA  . GLN A 177 ? 0.7442 1.0513 0.7802 0.1131  -0.0021 -0.0319 392 GLN A CA  
1158 C C   . GLN A 177 ? 0.7747 1.0154 0.7831 0.0905  0.0013  -0.0405 392 GLN A C   
1159 O O   . GLN A 177 ? 0.7685 1.0252 0.7757 0.0796  0.0129  -0.0445 392 GLN A O   
1160 C CB  . GLN A 177 ? 0.7694 1.0770 0.8052 0.1567  0.0154  -0.0197 392 GLN A CB  
1161 C CG  . GLN A 177 ? 0.7600 1.1542 0.8292 0.1893  0.0181  -0.0012 392 GLN A CG  
1162 C CD  . GLN A 177 ? 0.8469 1.2134 0.9114 0.2396  0.0419  0.0152  392 GLN A CD  
1163 O OE1 . GLN A 177 ? 0.8927 1.1760 0.9261 0.2432  0.0585  0.0062  392 GLN A OE1 
1164 N NE2 . GLN A 177 ? 0.8831 1.3197 0.9765 0.2779  0.0468  0.0402  392 GLN A NE2 
1165 N N   . LEU A 178 ? 0.7892 0.9638 0.7760 0.0842  -0.0083 -0.0407 393 LEU A N   
1166 C CA  . LEU A 178 ? 0.8125 0.9389 0.7742 0.0643  -0.0074 -0.0426 393 LEU A CA  
1167 C C   . LEU A 178 ? 0.7936 0.9420 0.7650 0.0357  -0.0038 -0.0453 393 LEU A C   
1168 O O   . LEU A 178 ? 0.7622 0.9392 0.7538 0.0218  -0.0069 -0.0496 393 LEU A O   
1169 C CB  . LEU A 178 ? 0.8177 0.8920 0.7643 0.0596  -0.0210 -0.0384 393 LEU A CB  
1170 C CG  . LEU A 178 ? 0.8285 0.8622 0.7492 0.0740  -0.0185 -0.0391 393 LEU A CG  
1171 C CD1 . LEU A 178 ? 0.8350 0.8854 0.7623 0.1027  -0.0039 -0.0405 393 LEU A CD1 
1172 C CD2 . LEU A 178 ? 0.8360 0.8401 0.7536 0.0728  -0.0328 -0.0350 393 LEU A CD2 
1173 N N   . PRO A 179 ? 0.7817 0.9169 0.7359 0.0235  0.0058  -0.0440 394 PRO A N   
1174 C CA  . PRO A 179 ? 0.7468 0.8989 0.7085 -0.0040 0.0150  -0.0451 394 PRO A CA  
1175 C C   . PRO A 179 ? 0.7667 0.8767 0.7246 -0.0234 0.0122  -0.0379 394 PRO A C   
1176 O O   . PRO A 179 ? 0.7622 0.8790 0.7296 -0.0478 0.0241  -0.0418 394 PRO A O   
1177 C CB  . PRO A 179 ? 0.7774 0.9256 0.7173 -0.0067 0.0276  -0.0427 394 PRO A CB  
1178 C CG  . PRO A 179 ? 0.7930 0.9021 0.7046 0.0104  0.0218  -0.0403 394 PRO A CG  
1179 C CD  . PRO A 179 ? 0.7840 0.8972 0.7106 0.0339  0.0141  -0.0443 394 PRO A CD  
1180 N N   . GLU A 180 ? 0.7661 0.8331 0.7111 -0.0141 0.0005  -0.0271 395 GLU A N   
1181 C CA  . GLU A 180 ? 0.7595 0.7872 0.7022 -0.0252 0.0024  -0.0131 395 GLU A CA  
1182 C C   . GLU A 180 ? 0.7833 0.7920 0.7348 -0.0140 -0.0101 -0.0114 395 GLU A C   
1183 O O   . GLU A 180 ? 0.7913 0.8011 0.7368 0.0022  -0.0238 -0.0123 395 GLU A O   
1184 C CB  . GLU A 180 ? 0.7650 0.7701 0.6825 -0.0253 0.0020  0.0081  395 GLU A CB  
1185 C CG  . GLU A 180 ? 0.8028 0.8216 0.7063 -0.0379 0.0161  0.0100  395 GLU A CG  
1186 C CD  . GLU A 180 ? 0.8046 0.8189 0.7207 -0.0588 0.0366  0.0095  395 GLU A CD  
1187 O OE1 . GLU A 180 ? 0.7790 0.8153 0.6900 -0.0720 0.0500  0.0044  395 GLU A OE1 
1188 O OE2 . GLU A 180 ? 0.7985 0.7849 0.7280 -0.0644 0.0428  0.0120  395 GLU A OE2 
1189 N N   . ARG A 181 ? 0.7616 0.7474 0.7250 -0.0240 -0.0015 -0.0095 396 ARG A N   
1190 C CA  . ARG A 181 ? 0.7903 0.7591 0.7621 -0.0131 -0.0110 -0.0078 396 ARG A CA  
1191 C C   . ARG A 181 ? 0.7900 0.7407 0.7509 0.0024  -0.0240 0.0141  396 ARG A C   
1192 O O   . ARG A 181 ? 0.7494 0.7004 0.7126 0.0139  -0.0378 0.0131  396 ARG A O   
1193 C CB  . ARG A 181 ? 0.8171 0.7574 0.8007 -0.0276 0.0075  -0.0120 396 ARG A CB  
1194 C CG  . ARG A 181 ? 0.8231 0.7935 0.8158 -0.0504 0.0168  -0.0403 396 ARG A CG  
1195 C CD  . ARG A 181 ? 0.8902 0.8215 0.8871 -0.0703 0.0400  -0.0502 396 ARG A CD  
1196 N NE  . ARG A 181 ? 0.9106 0.7831 0.9070 -0.0536 0.0491  -0.0253 396 ARG A NE  
1197 C CZ  . ARG A 181 ? 0.9261 0.7532 0.9179 -0.0567 0.0729  -0.0067 396 ARG A CZ  
1198 N NH1 . ARG A 181 ? 0.9664 0.7929 0.9505 -0.0797 0.0903  -0.0130 396 ARG A NH1 
1199 N NH2 . ARG A 181 ? 0.9593 0.7442 0.9556 -0.0346 0.0810  0.0222  396 ARG A NH2 
1200 N N   . TYR A 182 ? 0.7406 0.6829 0.6883 0.0005  -0.0203 0.0348  397 TYR A N   
1201 C CA  . TYR A 182 ? 0.7746 0.7186 0.7110 0.0105  -0.0353 0.0559  397 TYR A CA  
1202 C C   . TYR A 182 ? 0.7698 0.7323 0.6875 0.0118  -0.0504 0.0412  397 TYR A C   
1203 O O   . TYR A 182 ? 0.7548 0.7210 0.6647 0.0148  -0.0641 0.0485  397 TYR A O   
1204 C CB  . TYR A 182 ? 0.7678 0.7113 0.6919 0.0082  -0.0293 0.0862  397 TYR A CB  
1205 C CG  . TYR A 182 ? 0.7831 0.7464 0.6801 -0.0030 -0.0293 0.0823  397 TYR A CG  
1206 C CD1 . TYR A 182 ? 0.7902 0.7758 0.6613 -0.0064 -0.0446 0.0796  397 TYR A CD1 
1207 C CD2 . TYR A 182 ? 0.7922 0.7499 0.6869 -0.0138 -0.0103 0.0811  397 TYR A CD2 
1208 C CE1 . TYR A 182 ? 0.8202 0.8203 0.6628 -0.0182 -0.0403 0.0733  397 TYR A CE1 
1209 C CE2 . TYR A 182 ? 0.7996 0.7767 0.6694 -0.0238 -0.0079 0.0780  397 TYR A CE2 
1210 C CZ  . TYR A 182 ? 0.8317 0.8291 0.6753 -0.0249 -0.0225 0.0741  397 TYR A CZ  
1211 O OH  . TYR A 182 ? 0.8142 0.8275 0.6297 -0.0363 -0.0160 0.0672  397 TYR A OH  
1212 N N   . MET A 183 ? 0.7278 0.7014 0.6387 0.0094  -0.0449 0.0206  398 MET A N   
1213 C CA  . MET A 183 ? 0.8109 0.7875 0.7028 0.0140  -0.0510 0.0070  398 MET A CA  
1214 C C   . MET A 183 ? 0.7769 0.7478 0.6827 0.0266  -0.0566 -0.0035 398 MET A C   
1215 O O   . MET A 183 ? 0.7638 0.7228 0.6543 0.0294  -0.0623 -0.0078 398 MET A O   
1216 C CB  . MET A 183 ? 0.7888 0.7777 0.6682 0.0129  -0.0380 -0.0068 398 MET A CB  
1217 C CG  . MET A 183 ? 0.8094 0.8048 0.6691 -0.0014 -0.0315 0.0033  398 MET A CG  
1218 S SD  . MET A 183 ? 0.7618 0.7739 0.6101 -0.0006 -0.0128 -0.0152 398 MET A SD  
1219 C CE  . MET A 183 ? 0.8723 0.8915 0.6961 -0.0212 -0.0066 0.0017  398 MET A CE  
1220 N N   . MET A 184 ? 0.7825 0.7624 0.7139 0.0305  -0.0535 -0.0085 399 MET A N   
1221 C CA  . MET A 184 ? 0.7968 0.7751 0.7406 0.0410  -0.0603 -0.0136 399 MET A CA  
1222 C C   . MET A 184 ? 0.7805 0.7392 0.7245 0.0400  -0.0702 -0.0015 399 MET A C   
1223 O O   . MET A 184 ? 0.7260 0.6759 0.6629 0.0456  -0.0775 -0.0032 399 MET A O   
1224 C CB  . MET A 184 ? 0.7587 0.7589 0.7253 0.0375  -0.0548 -0.0220 399 MET A CB  
1225 C CG  . MET A 184 ? 0.7691 0.8047 0.7403 0.0348  -0.0455 -0.0311 399 MET A CG  
1226 S SD  . MET A 184 ? 0.6586 0.7300 0.6522 0.0167  -0.0388 -0.0438 399 MET A SD  
1227 C CE  . MET A 184 ? 0.7858 0.9222 0.7887 0.0181  -0.0319 -0.0511 399 MET A CE  
1228 N N   . ASN A 185 ? 0.7536 0.7056 0.7056 0.0338  -0.0677 0.0134  400 ASN A N   
1229 C CA  . ASN A 185 ? 0.7660 0.7113 0.7227 0.0369  -0.0758 0.0304  400 ASN A CA  
1230 C C   . ASN A 185 ? 0.7983 0.7520 0.7320 0.0321  -0.0882 0.0339  400 ASN A C   
1231 O O   . ASN A 185 ? 0.7633 0.7172 0.6973 0.0327  -0.0969 0.0344  400 ASN A O   
1232 C CB  . ASN A 185 ? 0.7794 0.7175 0.7478 0.0371  -0.0663 0.0532  400 ASN A CB  
1233 C CG  . ASN A 185 ? 0.8015 0.7189 0.7907 0.0379  -0.0497 0.0462  400 ASN A CG  
1234 O OD1 . ASN A 185 ? 0.7425 0.6626 0.7370 0.0367  -0.0511 0.0254  400 ASN A OD1 
1235 N ND2 . ASN A 185 ? 0.7673 0.6628 0.7654 0.0385  -0.0312 0.0631  400 ASN A ND2 
1236 N N   . SER A 186 ? 0.7698 0.7306 0.6800 0.0229  -0.0867 0.0329  401 SER A N   
1237 C CA  . SER A 186 ? 0.8071 0.7755 0.6878 0.0097  -0.0949 0.0307  401 SER A CA  
1238 C C   . SER A 186 ? 0.7883 0.7351 0.6574 0.0112  -0.0927 0.0086  401 SER A C   
1239 O O   . SER A 186 ? 0.7783 0.7238 0.6346 0.0002  -0.0995 0.0068  401 SER A O   
1240 C CB  . SER A 186 ? 0.8535 0.8307 0.7063 -0.0026 -0.0893 0.0287  401 SER A CB  
1241 O OG  . SER A 186 ? 0.8411 0.8428 0.6966 -0.0067 -0.0937 0.0569  401 SER A OG  
1242 N N   . VAL A 187 ? 0.7742 0.7071 0.6482 0.0247  -0.0813 -0.0060 402 VAL A N   
1243 C CA  . VAL A 187 ? 0.8745 0.7832 0.7385 0.0333  -0.0741 -0.0205 402 VAL A CA  
1244 C C   . VAL A 187 ? 0.8631 0.7680 0.7450 0.0393  -0.0826 -0.0154 402 VAL A C   
1245 O O   . VAL A 187 ? 0.8372 0.7192 0.7045 0.0375  -0.0797 -0.0217 402 VAL A O   
1246 C CB  . VAL A 187 ? 0.8388 0.7495 0.7108 0.0527  -0.0599 -0.0287 402 VAL A CB  
1247 C CG1 . VAL A 187 ? 0.8477 0.7353 0.7165 0.0710  -0.0503 -0.0340 402 VAL A CG1 
1248 C CG2 . VAL A 187 ? 0.8433 0.7528 0.6939 0.0472  -0.0474 -0.0363 402 VAL A CG2 
1249 N N   . LEU A 188 ? 0.8294 0.7517 0.7404 0.0445  -0.0892 -0.0051 403 LEU A N   
1250 C CA  . LEU A 188 ? 0.8247 0.7452 0.7528 0.0506  -0.0942 -0.0019 403 LEU A CA  
1251 C C   . LEU A 188 ? 0.8028 0.7269 0.7301 0.0393  -0.1040 0.0087  403 LEU A C   
1252 O O   . LEU A 188 ? 0.8353 0.7534 0.7677 0.0412  -0.1063 0.0082  403 LEU A O   
1253 C CB  . LEU A 188 ? 0.7785 0.7123 0.7336 0.0562  -0.0919 0.0007  403 LEU A CB  
1254 C CG  . LEU A 188 ? 0.7693 0.7167 0.7291 0.0640  -0.0847 -0.0106 403 LEU A CG  
1255 C CD1 . LEU A 188 ? 0.7950 0.7553 0.7744 0.0570  -0.0791 -0.0131 403 LEU A CD1 
1256 C CD2 . LEU A 188 ? 0.8137 0.7611 0.7711 0.0774  -0.0851 -0.0141 403 LEU A CD2 
1257 N N   . GLU A 189 ? 0.8098 0.7516 0.7309 0.0271  -0.1098 0.0206  404 GLU A N   
1258 C CA  . GLU A 189 ? 0.8334 0.7981 0.7591 0.0168  -0.1206 0.0351  404 GLU A CA  
1259 C C   . GLU A 189 ? 0.8713 0.8245 0.7730 0.0000  -0.1221 0.0210  404 GLU A C   
1260 O O   . GLU A 189 ? 0.8881 0.8639 0.7973 -0.0101 -0.1304 0.0300  404 GLU A O   
1261 C CB  . GLU A 189 ? 0.8071 0.8077 0.7301 0.0080  -0.1275 0.0565  404 GLU A CB  
1262 C CG  . GLU A 189 ? 0.8648 0.8691 0.7514 -0.0099 -0.1267 0.0476  404 GLU A CG  
1263 C CD  . GLU A 189 ? 0.9174 0.9689 0.8020 -0.0173 -0.1352 0.0759  404 GLU A CD  
1264 O OE1 . GLU A 189 ? 0.9353 1.0059 0.7852 -0.0408 -0.1389 0.0703  404 GLU A OE1 
1265 O OE2 . GLU A 189 ? 0.8920 0.9607 0.8075 0.0008  -0.1352 0.1051  404 GLU A OE2 
1266 N N   . ASN A 190 ? 0.8560 0.7726 0.7308 -0.0018 -0.1105 0.0002  405 ASN A N   
1267 C CA  . ASN A 190 ? 0.9227 0.8105 0.7704 -0.0176 -0.1031 -0.0148 405 ASN A CA  
1268 C C   . ASN A 190 ? 0.9570 0.8111 0.8127 0.0031  -0.0930 -0.0191 405 ASN A C   
1269 O O   . ASN A 190 ? 0.9796 0.7936 0.8100 -0.0036 -0.0789 -0.0307 405 ASN A O   
1270 C CB  . ASN A 190 ? 0.9842 0.8452 0.7895 -0.0351 -0.0891 -0.0339 405 ASN A CB  
1271 C CG  . ASN A 190 ? 0.9571 0.8579 0.7514 -0.0540 -0.0990 -0.0282 405 ASN A CG  
1272 O OD1 . ASN A 190 ? 0.9487 0.8927 0.7403 -0.0779 -0.1135 -0.0184 405 ASN A OD1 
1273 N ND2 . ASN A 190 ? 0.9335 0.8284 0.7230 -0.0428 -0.0913 -0.0311 405 ASN A ND2 
1274 N N   . PHE A 191 ? 0.8797 0.7484 0.7669 0.0261  -0.0974 -0.0096 406 PHE A N   
1275 C CA  . PHE A 191 ? 0.9259 0.7762 0.8188 0.0468  -0.0890 -0.0110 406 PHE A CA  
1276 C C   . PHE A 191 ? 0.9199 0.7894 0.8382 0.0501  -0.0975 -0.0020 406 PHE A C   
1277 O O   . PHE A 191 ? 0.8918 0.7874 0.8344 0.0534  -0.1040 0.0043  406 PHE A O   
1278 C CB  . PHE A 191 ? 0.8819 0.7415 0.7835 0.0675  -0.0834 -0.0122 406 PHE A CB  
1279 C CG  . PHE A 191 ? 0.8783 0.7437 0.7911 0.0895  -0.0790 -0.0080 406 PHE A CG  
1280 C CD1 . PHE A 191 ? 0.8811 0.7767 0.8179 0.0920  -0.0875 -0.0043 406 PHE A CD1 
1281 C CD2 . PHE A 191 ? 0.9073 0.7502 0.8052 0.1080  -0.0637 -0.0063 406 PHE A CD2 
1282 C CE1 . PHE A 191 ? 0.8589 0.7727 0.8024 0.1080  -0.0852 -0.0002 406 PHE A CE1 
1283 C CE2 . PHE A 191 ? 0.9044 0.7664 0.8136 0.1310  -0.0610 0.0043  406 PHE A CE2 
1284 C CZ  . PHE A 191 ? 0.8844 0.7876 0.8154 0.1285  -0.0742 0.0067  406 PHE A CZ  
1285 N N   . THR A 192 ? 0.8936 0.7453 0.8046 0.0484  -0.0934 -0.0018 407 THR A N   
1286 C CA  . THR A 192 ? 0.9805 0.8513 0.9136 0.0499  -0.0991 0.0056  407 THR A CA  
1287 C C   . THR A 192 ? 0.9803 0.8322 0.9054 0.0620  -0.0906 0.0067  407 THR A C   
1288 O O   . THR A 192 ? 0.9600 0.7772 0.8611 0.0663  -0.0785 0.0051  407 THR A O   
1289 C CB  . THR A 192 ? 1.0363 0.9232 0.9740 0.0285  -0.1062 0.0107  407 THR A CB  
1290 O OG1 . THR A 192 ? 1.0818 0.9404 0.9917 0.0107  -0.0988 0.0036  407 THR A OG1 
1291 C CG2 . THR A 192 ? 1.0175 0.9309 0.9594 0.0181  -0.1148 0.0157  407 THR A CG2 
1292 N N   . ILE A 193 ? 0.9751 0.8477 0.9188 0.0685  -0.0934 0.0109  408 ILE A N   
1293 C CA  . ILE A 193 ? 0.9679 0.8314 0.9033 0.0783  -0.0866 0.0158  408 ILE A CA  
1294 C C   . ILE A 193 ? 0.9449 0.8170 0.8907 0.0665  -0.0882 0.0187  408 ILE A C   
1295 O O   . ILE A 193 ? 0.8751 0.7718 0.8439 0.0609  -0.0934 0.0183  408 ILE A O   
1296 C CB  . ILE A 193 ? 0.9077 0.7987 0.8499 0.0965  -0.0868 0.0175  408 ILE A CB  
1297 C CG1 . ILE A 193 ? 0.8982 0.7899 0.8343 0.1090  -0.0843 0.0168  408 ILE A CG1 
1298 C CG2 . ILE A 193 ? 0.9111 0.8005 0.8418 0.1078  -0.0804 0.0284  408 ILE A CG2 
1299 C CD1 . ILE A 193 ? 0.8864 0.8187 0.8285 0.1255  -0.0847 0.0213  408 ILE A CD1 
1300 N N   . LEU A 194 ? 0.9399 0.7892 0.8692 0.0642  -0.0799 0.0237  409 LEU A N   
1301 C CA  . LEU A 194 ? 0.9449 0.8030 0.8821 0.0522  -0.0788 0.0270  409 LEU A CA  
1302 C C   . LEU A 194 ? 0.9061 0.7613 0.8332 0.0663  -0.0712 0.0347  409 LEU A C   
1303 O O   . LEU A 194 ? 0.8716 0.6977 0.7756 0.0781  -0.0615 0.0429  409 LEU A O   
1304 C CB  . LEU A 194 ? 0.9866 0.8226 0.9093 0.0272  -0.0742 0.0255  409 LEU A CB  
1305 C CG  . LEU A 194 ? 0.9635 0.8183 0.8976 0.0105  -0.0729 0.0294  409 LEU A CG  
1306 C CD1 . LEU A 194 ? 0.9168 0.8237 0.8887 0.0110  -0.0835 0.0325  409 LEU A CD1 
1307 C CD2 . LEU A 194 ? 1.0559 0.8887 0.9686 -0.0213 -0.0659 0.0246  409 LEU A CD2 
1308 N N   . GLN A 195 ? 0.8571 0.7431 0.8002 0.0667  -0.0730 0.0339  410 GLN A N   
1309 C CA  . GLN A 195 ? 0.8701 0.7674 0.8021 0.0776  -0.0679 0.0408  410 GLN A CA  
1310 C C   . GLN A 195 ? 0.8786 0.7773 0.8132 0.0649  -0.0614 0.0436  410 GLN A C   
1311 O O   . GLN A 195 ? 0.8442 0.7633 0.8021 0.0555  -0.0622 0.0363  410 GLN A O   
1312 C CB  . GLN A 195 ? 0.8298 0.7663 0.7727 0.0832  -0.0726 0.0315  410 GLN A CB  
1313 C CG  . GLN A 195 ? 0.8481 0.8052 0.7747 0.0993  -0.0737 0.0405  410 GLN A CG  
1314 C CD  . GLN A 195 ? 0.8590 0.8637 0.7920 0.0936  -0.0769 0.0271  410 GLN A CD  
1315 O OE1 . GLN A 195 ? 0.8631 0.8773 0.8029 0.0793  -0.0716 0.0140  410 GLN A OE1 
1316 N NE2 . GLN A 195 ? 0.8681 0.9046 0.7981 0.1025  -0.0825 0.0287  410 GLN A NE2 
1317 N N   . VAL A 196 ? 0.8702 0.7461 0.7820 0.0663  -0.0517 0.0564  411 VAL A N   
1318 C CA  . VAL A 196 ? 0.9077 0.7834 0.8195 0.0514  -0.0433 0.0599  411 VAL A CA  
1319 C C   . VAL A 196 ? 0.9117 0.8017 0.8064 0.0626  -0.0368 0.0713  411 VAL A C   
1320 O O   . VAL A 196 ? 0.8852 0.7563 0.7552 0.0786  -0.0308 0.0887  411 VAL A O   
1321 C CB  . VAL A 196 ? 0.9352 0.7669 0.8310 0.0336  -0.0333 0.0642  411 VAL A CB  
1322 C CG1 . VAL A 196 ? 0.9424 0.7877 0.8466 0.0120  -0.0266 0.0648  411 VAL A CG1 
1323 C CG2 . VAL A 196 ? 0.9771 0.7990 0.8797 0.0214  -0.0405 0.0532  411 VAL A CG2 
1324 N N   . VAL A 197 ? 0.8975 0.8223 0.8043 0.0557  -0.0353 0.0637  412 VAL A N   
1325 C CA  . VAL A 197 ? 0.9234 0.8726 0.8116 0.0603  -0.0294 0.0715  412 VAL A CA  
1326 C C   . VAL A 197 ? 0.9147 0.8560 0.8003 0.0455  -0.0165 0.0769  412 VAL A C   
1327 O O   . VAL A 197 ? 0.8785 0.8340 0.7890 0.0322  -0.0130 0.0644  412 VAL A O   
1328 C CB  . VAL A 197 ? 0.9024 0.8966 0.7992 0.0582  -0.0325 0.0528  412 VAL A CB  
1329 C CG1 . VAL A 197 ? 0.8920 0.9220 0.7617 0.0601  -0.0290 0.0608  412 VAL A CG1 
1330 C CG2 . VAL A 197 ? 0.8910 0.8925 0.7965 0.0657  -0.0437 0.0434  412 VAL A CG2 
1331 N N   . THR A 198 ? 0.9490 0.8678 0.8062 0.0495  -0.0070 0.0983  413 THR A N   
1332 C CA  . THR A 198 ? 0.9950 0.9039 0.8462 0.0329  0.0075  0.1049  413 THR A CA  
1333 C C   . THR A 198 ? 0.9749 0.9089 0.8001 0.0402  0.0148  0.1197  413 THR A C   
1334 O O   . THR A 198 ? 0.9499 0.9043 0.7565 0.0596  0.0090  0.1323  413 THR A O   
1335 C CB  . THR A 198 ? 1.0190 0.8687 0.8537 0.0233  0.0198  0.1176  413 THR A CB  
1336 O OG1 . THR A 198 ? 1.0509 0.8668 0.8537 0.0467  0.0273  0.1417  413 THR A OG1 
1337 C CG2 . THR A 198 ? 0.9821 0.8146 0.8360 0.0104  0.0124  0.1020  413 THR A CG2 
1338 N N   . ASN A 199 ? 1.0245 0.9659 0.8491 0.0235  0.0275  0.1196  414 ASN A N   
1339 C CA  . ASN A 199 ? 1.0382 1.0016 0.8335 0.0261  0.0372  0.1358  414 ASN A CA  
1340 C C   . ASN A 199 ? 1.0634 0.9787 0.8265 0.0366  0.0493  0.1699  414 ASN A C   
1341 O O   . ASN A 199 ? 1.0912 0.9575 0.8527 0.0210  0.0634  0.1741  414 ASN A O   
1342 C CB  . ASN A 199 ? 1.0403 1.0251 0.8477 0.0044  0.0501  0.1231  414 ASN A CB  
1343 C CG  . ASN A 199 ? 1.0597 1.0685 0.8340 0.0027  0.0622  0.1384  414 ASN A CG  
1344 O OD1 . ASN A 199 ? 1.0830 1.0824 0.8230 0.0167  0.0644  0.1682  414 ASN A OD1 
1345 N ND2 . ASN A 199 ? 1.0221 1.0669 0.8064 -0.0119 0.0718  0.1192  414 ASN A ND2 
1346 N N   . ARG A 200 ? 1.0478 0.9775 0.7854 0.0627  0.0462  0.1952  415 ARG A N   
1347 C CA  . ARG A 200 ? 1.1232 0.9960 0.8340 0.0827  0.0617  0.2315  415 ARG A CA  
1348 C C   . ARG A 200 ? 1.1663 1.0023 0.8525 0.0698  0.0868  0.2519  415 ARG A C   
1349 O O   . ARG A 200 ? 1.2024 0.9631 0.8699 0.0733  0.1089  0.2722  415 ARG A O   
1350 C CB  . ARG A 200 ? 1.1240 1.0362 0.8161 0.1190  0.0549  0.2632  415 ARG A CB  
1351 C CG  . ARG A 200 ? 1.1422 0.9860 0.8123 0.1480  0.0763  0.3031  415 ARG A CG  
1352 C CD  . ARG A 200 ? 1.1870 1.0267 0.8239 0.1614  0.0957  0.3452  415 ARG A CD  
1353 N NE  . ARG A 200 ? 1.2161 1.1197 0.8405 0.2019  0.0876  0.3849  415 ARG A NE  
1354 C CZ  . ARG A 200 ? 1.1660 1.1273 0.7651 0.2119  0.0891  0.4181  415 ARG A CZ  
1355 N NH1 . ARG A 200 ? 1.1970 1.1603 0.7813 0.1832  0.0973  0.4107  415 ARG A NH1 
1356 N NH2 . ARG A 200 ? 1.1992 1.2236 0.7876 0.2523  0.0831  0.4625  415 ARG A NH2 
1357 N N   . ASP A 201 ? 1.1313 1.0147 0.8140 0.0534  0.0880  0.2463  416 ASP A N   
1358 C CA  . ASP A 201 ? 1.1650 1.0184 0.8211 0.0418  0.1130  0.2693  416 ASP A CA  
1359 C C   . ASP A 201 ? 1.1925 1.0093 0.8677 0.0043  0.1256  0.2459  416 ASP A C   
1360 O O   . ASP A 201 ? 1.2708 1.0312 0.9242 -0.0092 0.1510  0.2637  416 ASP A O   
1361 C CB  . ASP A 201 ? 1.1569 1.0801 0.7941 0.0406  0.1121  0.2778  416 ASP A CB  
1362 C CG  . ASP A 201 ? 1.1630 1.1332 0.7735 0.0745  0.1023  0.3113  416 ASP A CG  
1363 O OD1 . ASP A 201 ? 1.1678 1.1096 0.7757 0.1042  0.1005  0.3343  416 ASP A OD1 
1364 O OD2 . ASP A 201 ? 1.1799 1.2194 0.7705 0.0711  0.0985  0.3167  416 ASP A OD2 
1365 N N   . THR A 202 ? 1.1614 1.0108 0.8768 -0.0131 0.1103  0.2088  417 THR A N   
1366 C CA  . THR A 202 ? 1.1703 1.0103 0.9094 -0.0483 0.1195  0.1901  417 THR A CA  
1367 C C   . THR A 202 ? 1.1900 0.9974 0.9505 -0.0607 0.1126  0.1730  417 THR A C   
1368 O O   . THR A 202 ? 1.2061 1.0070 0.9809 -0.0941 0.1213  0.1618  417 THR A O   
1369 C CB  . THR A 202 ? 1.1089 1.0191 0.8815 -0.0588 0.1130  0.1657  417 THR A CB  
1370 O OG1 . THR A 202 ? 1.0931 1.0375 0.8846 -0.0393 0.0923  0.1482  417 THR A OG1 
1371 C CG2 . THR A 202 ? 1.1037 1.0416 0.8513 -0.0599 0.1270  0.1784  417 THR A CG2 
1372 N N   . GLN A 203 ? 1.2359 1.0313 0.9989 -0.0381 0.0971  0.1700  418 GLN A N   
1373 C CA  . GLN A 203 ? 1.2088 0.9771 0.9877 -0.0487 0.0895  0.1533  418 GLN A CA  
1374 C C   . GLN A 203 ? 1.1665 0.9953 0.9926 -0.0599 0.0702  0.1269  418 GLN A C   
1375 O O   . GLN A 203 ? 1.1700 0.9915 1.0119 -0.0709 0.0611  0.1135  418 GLN A O   
1376 C CB  . GLN A 203 ? 1.2533 0.9582 1.0130 -0.0823 0.1124  0.1541  418 GLN A CB  
1377 C CG  . GLN A 203 ? 1.3504 0.9843 1.0625 -0.0749 0.1423  0.1837  418 GLN A CG  
1378 C CD  . GLN A 203 ? 1.4090 1.0142 1.0994 -0.0283 0.1419  0.2072  418 GLN A CD  
1379 O OE1 . GLN A 203 ? 1.3678 1.0316 1.0695 0.0015  0.1211  0.2127  418 GLN A OE1 
1380 N NE2 . GLN A 203 ? 1.5462 1.0625 1.2044 -0.0230 0.1683  0.2215  418 GLN A NE2 
1381 N N   . GLU A 204 ? 1.0747 0.9615 0.9224 -0.0563 0.0667  0.1204  419 GLU A N   
1382 C CA  . GLU A 204 ? 1.0144 0.9521 0.9085 -0.0589 0.0543  0.1007  419 GLU A CA  
1383 C C   . GLU A 204 ? 0.9610 0.9014 0.8644 -0.0357 0.0360  0.0915  419 GLU A C   
1384 O O   . GLU A 204 ? 0.9606 0.8916 0.8409 -0.0150 0.0317  0.0965  419 GLU A O   
1385 C CB  . GLU A 204 ? 0.9940 0.9823 0.9068 -0.0581 0.0634  0.0951  419 GLU A CB  
1386 C CG  . GLU A 204 ? 1.0417 1.0300 0.9192 -0.0472 0.0724  0.1035  419 GLU A CG  
1387 C CD  . GLU A 204 ? 1.0083 1.0382 0.8972 -0.0563 0.0893  0.0973  419 GLU A CD  
1388 O OE1 . GLU A 204 ? 1.0010 1.0393 0.9035 -0.0770 0.1016  0.1017  419 GLU A OE1 
1389 O OE2 . GLU A 204 ? 1.0064 1.0620 0.8891 -0.0457 0.0925  0.0863  419 GLU A OE2 
1390 N N   . LEU A 205 ? 0.9278 0.8888 0.8661 -0.0403 0.0254  0.0802  420 LEU A N   
1391 C CA  . LEU A 205 ? 0.8947 0.8594 0.8454 -0.0215 0.0101  0.0711  420 LEU A CA  
1392 C C   . LEU A 205 ? 0.8577 0.8579 0.8281 -0.0071 0.0132  0.0603  420 LEU A C   
1393 O O   . LEU A 205 ? 0.8311 0.8634 0.8293 -0.0115 0.0240  0.0571  420 LEU A O   
1394 C CB  . LEU A 205 ? 0.8617 0.8366 0.8388 -0.0326 -0.0005 0.0669  420 LEU A CB  
1395 C CG  . LEU A 205 ? 0.8508 0.8304 0.8415 -0.0123 -0.0136 0.0591  420 LEU A CG  
1396 C CD1 . LEU A 205 ? 0.8585 0.7930 0.8182 -0.0079 -0.0211 0.0603  420 LEU A CD1 
1397 C CD2 . LEU A 205 ? 0.8345 0.8530 0.8665 -0.0154 -0.0203 0.0585  420 LEU A CD2 
1398 N N   . LEU A 206 ? 0.8150 0.8100 0.7702 0.0085  0.0073  0.0539  421 LEU A N   
1399 C CA  . LEU A 206 ? 0.8835 0.9029 0.8494 0.0154  0.0149  0.0376  421 LEU A CA  
1400 C C   . LEU A 206 ? 0.8294 0.8489 0.8213 0.0246  0.0088  0.0265  421 LEU A C   
1401 O O   . LEU A 206 ? 0.7824 0.8148 0.8017 0.0283  0.0224  0.0170  421 LEU A O   
1402 C CB  . LEU A 206 ? 0.8992 0.9257 0.8278 0.0187  0.0151  0.0351  421 LEU A CB  
1403 C CG  . LEU A 206 ? 0.9087 0.9391 0.8080 0.0123  0.0239  0.0500  421 LEU A CG  
1404 C CD1 . LEU A 206 ? 0.9188 0.9711 0.7814 0.0179  0.0196  0.0533  421 LEU A CD1 
1405 C CD2 . LEU A 206 ? 0.8996 0.9491 0.8138 0.0008  0.0438  0.0419  421 LEU A CD2 
1406 N N   . LEU A 207 ? 0.8627 0.8644 0.8461 0.0299  -0.0078 0.0299  422 LEU A N   
1407 C CA  . LEU A 207 ? 0.8286 0.8277 0.8284 0.0381  -0.0142 0.0205  422 LEU A CA  
1408 C C   . LEU A 207 ? 0.8185 0.7991 0.8157 0.0390  -0.0306 0.0300  422 LEU A C   
1409 O O   . LEU A 207 ? 0.8065 0.7687 0.7759 0.0405  -0.0364 0.0371  422 LEU A O   
1410 C CB  . LEU A 207 ? 0.7961 0.8004 0.7753 0.0410  -0.0139 0.0064  422 LEU A CB  
1411 C CG  . LEU A 207 ? 0.8113 0.8221 0.8031 0.0380  0.0046  -0.0142 422 LEU A CG  
1412 C CD1 . LEU A 207 ? 0.8320 0.8482 0.8053 0.0337  0.0011  -0.0307 422 LEU A CD1 
1413 C CD2 . LEU A 207 ? 0.8248 0.8270 0.8564 0.0464  0.0117  -0.0096 422 LEU A CD2 
1414 N N   . CYS A 208 ? 0.8079 0.7940 0.8325 0.0394  -0.0352 0.0315  423 CYS A N   
1415 C CA  . CYS A 208 ? 0.8100 0.7816 0.8297 0.0371  -0.0494 0.0358  423 CYS A CA  
1416 C C   . CYS A 208 ? 0.7910 0.7680 0.8294 0.0474  -0.0529 0.0308  423 CYS A C   
1417 O O   . CYS A 208 ? 0.7898 0.7866 0.8592 0.0516  -0.0476 0.0358  423 CYS A O   
1418 C CB  . CYS A 208 ? 0.8171 0.7988 0.8459 0.0197  -0.0528 0.0450  423 CYS A CB  
1419 S SG  . CYS A 208 ? 0.7751 0.7380 0.7889 0.0086  -0.0666 0.0447  423 CYS A SG  
1420 N N   . THR A 209 ? 0.7618 0.7234 0.7825 0.0536  -0.0590 0.0238  424 THR A N   
1421 C CA  . THR A 209 ? 0.8091 0.7705 0.8422 0.0602  -0.0608 0.0184  424 THR A CA  
1422 C C   . THR A 209 ? 0.8025 0.7527 0.8262 0.0587  -0.0742 0.0228  424 THR A C   
1423 O O   . THR A 209 ? 0.7590 0.6929 0.7577 0.0594  -0.0786 0.0222  424 THR A O   
1424 C CB  . THR A 209 ? 0.8151 0.7768 0.8360 0.0629  -0.0553 0.0034  424 THR A CB  
1425 O OG1 . THR A 209 ? 0.8479 0.8187 0.8685 0.0591  -0.0405 -0.0053 424 THR A OG1 
1426 C CG2 . THR A 209 ? 0.8026 0.7590 0.8378 0.0654  -0.0510 -0.0033 424 THR A CG2 
1427 N N   . ALA A 210 ? 0.8369 0.7966 0.8800 0.0588  -0.0776 0.0290  425 ALA A N   
1428 C CA  . ALA A 210 ? 0.8153 0.7684 0.8490 0.0554  -0.0884 0.0309  425 ALA A CA  
1429 C C   . ALA A 210 ? 0.8049 0.7529 0.8428 0.0647  -0.0861 0.0249  425 ALA A C   
1430 O O   . ALA A 210 ? 0.8114 0.7647 0.8707 0.0711  -0.0758 0.0266  425 ALA A O   
1431 C CB  . ALA A 210 ? 0.8237 0.8033 0.8738 0.0463  -0.0950 0.0448  425 ALA A CB  
1432 N N   . TYR A 211 ? 0.7756 0.7109 0.7932 0.0656  -0.0912 0.0180  426 TYR A N   
1433 C CA  . TYR A 211 ? 0.8001 0.7349 0.8200 0.0697  -0.0893 0.0115  426 TYR A CA  
1434 C C   . TYR A 211 ? 0.8379 0.7708 0.8546 0.0667  -0.0967 0.0178  426 TYR A C   
1435 O O   . TYR A 211 ? 0.8336 0.7587 0.8323 0.0605  -0.1030 0.0188  426 TYR A O   
1436 C CB  . TYR A 211 ? 0.7835 0.7209 0.7867 0.0737  -0.0893 0.0013  426 TYR A CB  
1437 C CG  . TYR A 211 ? 0.8055 0.7553 0.8070 0.0733  -0.0833 -0.0045 426 TYR A CG  
1438 C CD1 . TYR A 211 ? 0.7971 0.7577 0.8059 0.0664  -0.0728 -0.0178 426 TYR A CD1 
1439 C CD2 . TYR A 211 ? 0.8203 0.7680 0.8092 0.0765  -0.0848 0.0024  426 TYR A CD2 
1440 C CE1 . TYR A 211 ? 0.8201 0.7961 0.8216 0.0611  -0.0663 -0.0261 426 TYR A CE1 
1441 C CE2 . TYR A 211 ? 0.8335 0.7972 0.8176 0.0752  -0.0796 -0.0010 426 TYR A CE2 
1442 C CZ  . TYR A 211 ? 0.8351 0.8164 0.8248 0.0667  -0.0714 -0.0161 426 TYR A CZ  
1443 O OH  . TYR A 211 ? 0.8209 0.8221 0.8003 0.0609  -0.0654 -0.0220 426 TYR A OH  
1444 N N   . VAL A 212 ? 0.7716 0.7077 0.8022 0.0691  -0.0923 0.0214  427 VAL A N   
1445 C CA  . VAL A 212 ? 0.8075 0.7454 0.8331 0.0665  -0.0974 0.0275  427 VAL A CA  
1446 C C   . VAL A 212 ? 0.7928 0.7231 0.8209 0.0686  -0.0879 0.0191  427 VAL A C   
1447 O O   . VAL A 212 ? 0.7569 0.6812 0.7954 0.0692  -0.0749 0.0115  427 VAL A O   
1448 C CB  . VAL A 212 ? 0.7972 0.7550 0.8393 0.0665  -0.1004 0.0494  427 VAL A CB  
1449 C CG1 . VAL A 212 ? 0.8270 0.8041 0.8676 0.0572  -0.1099 0.0558  427 VAL A CG1 
1450 C CG2 . VAL A 212 ? 0.7836 0.7386 0.8529 0.0792  -0.0844 0.0596  427 VAL A CG2 
1451 N N   . PHE A 213 ? 0.7793 0.7097 0.7957 0.0657  -0.0916 0.0185  428 PHE A N   
1452 C CA  . PHE A 213 ? 0.7788 0.7083 0.7927 0.0633  -0.0839 0.0064  428 PHE A CA  
1453 C C   . PHE A 213 ? 0.7678 0.6943 0.7816 0.0602  -0.0800 0.0148  428 PHE A C   
1454 O O   . PHE A 213 ? 0.7346 0.6661 0.7405 0.0594  -0.0883 0.0276  428 PHE A O   
1455 C CB  . PHE A 213 ? 0.7994 0.7385 0.7973 0.0658  -0.0892 -0.0048 428 PHE A CB  
1456 C CG  . PHE A 213 ? 0.7936 0.7385 0.7890 0.0714  -0.0912 -0.0090 428 PHE A CG  
1457 C CD1 . PHE A 213 ? 0.8097 0.7418 0.7958 0.0748  -0.0964 -0.0025 428 PHE A CD1 
1458 C CD2 . PHE A 213 ? 0.7779 0.7446 0.7775 0.0695  -0.0867 -0.0195 428 PHE A CD2 
1459 C CE1 . PHE A 213 ? 0.8153 0.7498 0.7971 0.0808  -0.0960 -0.0029 428 PHE A CE1 
1460 C CE2 . PHE A 213 ? 0.7655 0.7441 0.7603 0.0751  -0.0890 -0.0194 428 PHE A CE2 
1461 C CZ  . PHE A 213 ? 0.7694 0.7289 0.7558 0.0831  -0.0931 -0.0095 428 PHE A CZ  
1462 N N   . GLU A 214 ? 0.7994 0.7195 0.8191 0.0544  -0.0657 0.0066  429 GLU A N   
1463 C CA  . GLU A 214 ? 0.7889 0.7051 0.8050 0.0482  -0.0580 0.0096  429 GLU A CA  
1464 C C   . GLU A 214 ? 0.8086 0.7347 0.8236 0.0353  -0.0483 -0.0130 429 GLU A C   
1465 O O   . GLU A 214 ? 0.8119 0.7534 0.8279 0.0326  -0.0502 -0.0275 429 GLU A O   
1466 C CB  . GLU A 214 ? 0.7706 0.6640 0.7988 0.0517  -0.0425 0.0299  429 GLU A CB  
1467 C CG  . GLU A 214 ? 0.7835 0.6878 0.8167 0.0641  -0.0536 0.0577  429 GLU A CG  
1468 C CD  . GLU A 214 ? 0.8239 0.7167 0.8692 0.0739  -0.0384 0.0875  429 GLU A CD  
1469 O OE1 . GLU A 214 ? 0.8305 0.6917 0.8782 0.0704  -0.0144 0.0850  429 GLU A OE1 
1470 O OE2 . GLU A 214 ? 0.8344 0.7529 0.8860 0.0843  -0.0490 0.1155  429 GLU A OE2 
1471 N N   . VAL A 215 ? 0.7093 0.6335 0.7217 0.0246  -0.0377 -0.0153 430 VAL A N   
1472 C CA  . VAL A 215 ? 0.8022 0.7468 0.8146 0.0056  -0.0276 -0.0376 430 VAL A CA  
1473 C C   . VAL A 215 ? 0.8648 0.7732 0.8807 -0.0127 0.0002  -0.0428 430 VAL A C   
1474 O O   . VAL A 215 ? 0.8367 0.7070 0.8548 -0.0053 0.0121  -0.0226 430 VAL A O   
1475 C CB  . VAL A 215 ? 0.8091 0.7863 0.8154 0.0031  -0.0330 -0.0408 430 VAL A CB  
1476 C CG1 . VAL A 215 ? 0.7601 0.7593 0.7603 0.0237  -0.0517 -0.0359 430 VAL A CG1 
1477 C CG2 . VAL A 215 ? 0.8037 0.7555 0.8047 -0.0007 -0.0229 -0.0267 430 VAL A CG2 
1478 N N   . SER A 216 ? 0.8869 0.8080 0.9014 -0.0375 0.0132  -0.0689 431 SER A N   
1479 C CA  . SER A 216 ? 0.9327 0.8135 0.9441 -0.0638 0.0468  -0.0821 431 SER A CA  
1480 C C   . SER A 216 ? 0.9513 0.8643 0.9571 -0.0924 0.0534  -0.0988 431 SER A C   
1481 O O   . SER A 216 ? 0.9302 0.9079 0.9380 -0.0913 0.0321  -0.1034 431 SER A O   
1482 C CB  . SER A 216 ? 0.9300 0.7982 0.9382 -0.0816 0.0633  -0.1058 431 SER A CB  
1483 O OG  . SER A 216 ? 0.9400 0.7644 0.9391 -0.1149 0.1022  -0.1260 431 SER A OG  
1484 N N   . THR A 217 ? 1.0074 0.8743 1.0070 -0.1168 0.0867  -0.1059 432 THR A N   
1485 C CA  . THR A 217 ? 1.0490 0.9503 1.0431 -0.1523 0.0964  -0.1262 432 THR A CA  
1486 C C   . THR A 217 ? 1.0769 1.0325 1.0667 -0.1883 0.0973  -0.1625 432 THR A C   
1487 O O   . THR A 217 ? 1.0537 1.0136 1.0422 -0.1844 0.0915  -0.1710 432 THR A O   
1488 C CB  . THR A 217 ? 1.0860 0.9161 1.0714 -0.1711 0.1356  -0.1228 432 THR A CB  
1489 O OG1 . THR A 217 ? 1.1194 0.8893 1.0957 -0.1944 0.1719  -0.1431 432 THR A OG1 
1490 C CG2 . THR A 217 ? 1.0410 0.8262 1.0303 -0.1309 0.1326  -0.0796 432 THR A CG2 
1491 N N   . SER A 218 ? 1.2178 1.2244 1.2046 -0.2263 0.1043  -0.1838 433 SER A N   
1492 C CA  . SER A 218 ? 1.1634 1.2414 1.1451 -0.2664 0.1034  -0.2176 433 SER A CA  
1493 C C   . SER A 218 ? 1.1888 1.2063 1.1490 -0.3161 0.1459  -0.2518 433 SER A C   
1494 O O   . SER A 218 ? 1.1471 1.1974 1.0969 -0.3415 0.1467  -0.2779 433 SER A O   
1495 C CB  . SER A 218 ? 1.1674 1.3458 1.1581 -0.2879 0.0916  -0.2252 433 SER A CB  
1496 O OG  . SER A 218 ? 1.1995 1.3544 1.1969 -0.2688 0.0929  -0.2031 433 SER A OG  
1497 N N   . GLU A 219 ? 1.1263 1.0524 1.0766 -0.3312 0.1852  -0.2520 434 GLU A N   
1498 C CA  . GLU A 219 ? 1.1497 0.9963 1.0764 -0.3758 0.2357  -0.2843 434 GLU A CA  
1499 C C   . GLU A 219 ? 1.1636 0.9294 1.0887 -0.3436 0.2493  -0.2738 434 GLU A C   
1500 O O   . GLU A 219 ? 1.1695 0.8879 1.0740 -0.3786 0.2861  -0.3067 434 GLU A O   
1501 C CB  . GLU A 219 ? 1.2076 0.9728 1.1228 -0.4009 0.2811  -0.2849 434 GLU A CB  
1502 C CG  . GLU A 219 ? 1.2603 0.9472 1.1870 -0.3461 0.2862  -0.2348 434 GLU A CG  
1503 C CD  . GLU A 219 ? 1.3445 0.9367 1.2549 -0.3728 0.3412  -0.2341 434 GLU A CD  
1504 O OE1 . GLU A 219 ? 1.3465 0.9027 1.2336 -0.4335 0.3854  -0.2755 434 GLU A OE1 
1505 O OE2 . GLU A 219 ? 1.3560 0.9123 1.2745 -0.3360 0.3413  -0.1918 434 GLU A OE2 
1506 N N   . ARG A 220 ? 1.0753 0.8267 1.0205 -0.2809 0.2232  -0.2306 435 ARG A N   
1507 C CA  . ARG A 220 ? 1.0788 0.7731 1.0279 -0.2489 0.2322  -0.2183 435 ARG A CA  
1508 C C   . ARG A 220 ? 1.0325 0.7958 0.9817 -0.2478 0.2016  -0.2333 435 ARG A C   
1509 O O   . ARG A 220 ? 1.0499 0.7733 0.9911 -0.2510 0.2225  -0.2470 435 ARG A O   
1510 C CB  . ARG A 220 ? 1.0402 0.7034 1.0104 -0.1879 0.2164  -0.1660 435 ARG A CB  
1511 C CG  . ARG A 220 ? 1.0447 0.6114 1.0144 -0.1771 0.2601  -0.1419 435 ARG A CG  
1512 C CD  . ARG A 220 ? 1.0339 0.5689 1.0244 -0.1180 0.2538  -0.0927 435 ARG A CD  
1513 N NE  . ARG A 220 ? 1.0795 0.5788 1.0743 -0.1064 0.2727  -0.0991 435 ARG A NE  
1514 C CZ  . ARG A 220 ? 1.0700 0.5195 1.0822 -0.0638 0.2915  -0.0627 435 ARG A CZ  
1515 N NH1 . ARG A 220 ? 1.0722 0.5003 1.0977 -0.0293 0.2958  -0.0145 435 ARG A NH1 
1516 N NH2 . ARG A 220 ? 1.0269 0.4568 1.0442 -0.0546 0.3058  -0.0722 435 ARG A NH2 
1517 N N   . GLY A 221 ? 1.0138 0.8779 0.9711 -0.2426 0.1569  -0.2300 436 GLY A N   
1518 C CA  . GLY A 221 ? 0.9654 0.8984 0.9212 -0.2410 0.1300  -0.2396 436 GLY A CA  
1519 C C   . GLY A 221 ? 0.9164 0.8283 0.8862 -0.1881 0.1092  -0.2080 436 GLY A C   
1520 O O   . GLY A 221 ? 0.9061 0.7495 0.8862 -0.1571 0.1198  -0.1824 436 GLY A O   
1521 N N   . ALA A 222 ? 0.8846 0.8647 0.8552 -0.1782 0.0789  -0.2073 437 ALA A N   
1522 C CA  . ALA A 222 ? 0.8734 0.8411 0.8550 -0.1339 0.0585  -0.1801 437 ALA A CA  
1523 C C   . ALA A 222 ? 0.8492 0.7411 0.8292 -0.1296 0.0880  -0.1831 437 ALA A C   
1524 O O   . ALA A 222 ? 0.8725 0.7363 0.8363 -0.1640 0.1211  -0.2139 437 ALA A O   
1525 C CB  . ALA A 222 ? 0.8211 0.8690 0.7993 -0.1285 0.0286  -0.1800 437 ALA A CB  
1526 N N   . GLN A 223 ? 0.8317 0.6916 0.8283 -0.0883 0.0788  -0.1513 438 GLN A N   
1527 C CA  . GLN A 223 ? 0.8872 0.6822 0.8907 -0.0748 0.1071  -0.1451 438 GLN A CA  
1528 C C   . GLN A 223 ? 0.9007 0.7115 0.9204 -0.0364 0.0802  -0.1155 438 GLN A C   
1529 O O   . GLN A 223 ? 0.8653 0.7161 0.8895 -0.0202 0.0460  -0.0978 438 GLN A O   
1530 C CB  . GLN A 223 ? 0.9265 0.6502 0.9390 -0.0660 0.1397  -0.1295 438 GLN A CB  
1531 C CG  . GLN A 223 ? 0.9654 0.6183 0.9840 -0.0552 0.1823  -0.1273 438 GLN A CG  
1532 C CD  . GLN A 223 ? 1.0213 0.6079 1.0547 -0.0317 0.2135  -0.0965 438 GLN A CD  
1533 O OE1 . GLN A 223 ? 1.0396 0.5662 1.0837 -0.0128 0.2525  -0.0851 438 GLN A OE1 
1534 N NE2 . GLN A 223 ? 0.9956 0.5946 1.0305 -0.0293 0.1984  -0.0791 438 GLN A NE2 
1535 N N   . HIS A 224 ? 0.8659 0.6427 0.8937 -0.0239 0.0998  -0.1113 439 HIS A N   
1536 C CA  . HIS A 224 ? 0.9070 0.7018 0.9515 0.0075  0.0775  -0.0842 439 HIS A CA  
1537 C C   . HIS A 224 ? 0.9456 0.6933 1.0096 0.0281  0.1091  -0.0688 439 HIS A C   
1538 O O   . HIS A 224 ? 0.9515 0.6476 1.0110 0.0172  0.1513  -0.0852 439 HIS A O   
1539 C CB  . HIS A 224 ? 0.8780 0.7191 0.9092 -0.0009 0.0567  -0.0981 439 HIS A CB  
1540 C CG  . HIS A 224 ? 0.9153 0.7455 0.9298 -0.0267 0.0843  -0.1304 439 HIS A CG  
1541 N ND1 . HIS A 224 ? 0.8971 0.7003 0.9180 -0.0176 0.1062  -0.1306 439 HIS A ND1 
1542 C CD2 . HIS A 224 ? 0.8903 0.7349 0.8801 -0.0651 0.0967  -0.1655 439 HIS A CD2 
1543 C CE1 . HIS A 224 ? 0.9286 0.7234 0.9261 -0.0494 0.1324  -0.1665 439 HIS A CE1 
1544 N NE2 . HIS A 224 ? 0.9169 0.7386 0.8941 -0.0811 0.1265  -0.1889 439 HIS A NE2 
1545 N N   A HIS A 225 ? 0.8990 0.6654 0.9850 0.0577  0.0916  -0.0366 440 HIS A N   
1546 N N   B HIS A 225 ? 0.9517 0.7194 1.0373 0.0574  0.0908  -0.0370 440 HIS A N   
1547 C CA  A HIS A 225 ? 0.9326 0.6740 1.0428 0.0817  0.1187  -0.0180 440 HIS A CA  
1548 C CA  B HIS A 225 ? 0.9522 0.6970 1.0644 0.0841  0.1154  -0.0139 440 HIS A CA  
1549 C C   A HIS A 225 ? 0.8886 0.6765 1.0101 0.0943  0.0919  -0.0043 440 HIS A C   
1550 C C   B HIS A 225 ? 0.9022 0.6923 1.0233 0.0940  0.0900  -0.0042 440 HIS A C   
1551 O O   A HIS A 225 ? 0.8706 0.6978 0.9966 0.1013  0.0574  0.0155  440 HIS A O   
1552 O O   B HIS A 225 ? 0.9025 0.7331 1.0262 0.0994  0.0545  0.0132  440 HIS A O   
1553 C CB  A HIS A 225 ? 0.9719 0.6893 1.1062 0.1089  0.1351  0.0191  440 HIS A CB  
1554 C CB  B HIS A 225 ? 0.9665 0.7025 1.1019 0.1109  0.1195  0.0263  440 HIS A CB  
1555 C CG  A HIS A 225 ? 1.0167 0.6623 1.1453 0.1029  0.1851  0.0079  440 HIS A CG  
1556 C CG  B HIS A 225 ? 0.9788 0.6876 1.1449 0.1428  0.1557  0.0547  440 HIS A CG  
1557 N ND1 A HIS A 225 ? 1.0181 0.6406 1.1190 0.0697  0.1923  -0.0224 440 HIS A ND1 
1558 N ND1 B HIS A 225 ? 1.0022 0.6836 1.1862 0.1672  0.1790  0.0889  440 HIS A ND1 
1559 C CD2 A HIS A 225 ? 1.0280 0.6162 1.1735 0.1244  0.2351  0.0219  440 HIS A CD2 
1560 C CD2 B HIS A 225 ? 0.9802 0.6894 1.1646 0.1583  0.1742  0.0589  440 HIS A CD2 
1561 C CE1 A HIS A 225 ? 1.0390 0.5879 1.1365 0.0659  0.2450  -0.0296 440 HIS A CE1 
1562 C CE1 B HIS A 225 ? 1.0134 0.6791 1.2273 0.1996  0.2120  0.1149  440 HIS A CE1 
1563 N NE2 A HIS A 225 ? 1.0388 0.5602 1.1627 0.1013  0.2739  -0.0022 440 HIS A NE2 
1564 N NE2 B HIS A 225 ? 1.0094 0.6922 1.2249 0.1942  0.2099  0.0958  440 HIS A NE2 
1565 N N   . ILE A 226 ? 0.9522 0.7326 1.0747 0.0930  0.1111  -0.0175 441 ILE A N   
1566 C CA  . ILE A 226 ? 0.9191 0.7400 1.0480 0.0987  0.0911  -0.0100 441 ILE A CA  
1567 C C   . ILE A 226 ? 0.9000 0.7320 1.0680 0.1299  0.1021  0.0258  441 ILE A C   
1568 O O   . ILE A 226 ? 0.9272 0.7235 1.1142 0.1477  0.1417  0.0341  441 ILE A O   
1569 C CB  . ILE A 226 ? 0.9041 0.7192 1.0103 0.0781  0.1063  -0.0437 441 ILE A CB  
1570 C CG1 . ILE A 226 ? 0.8830 0.7081 0.9534 0.0475  0.0922  -0.0736 441 ILE A CG1 
1571 C CG2 . ILE A 226 ? 0.8792 0.7298 0.9926 0.0848  0.0927  -0.0340 441 ILE A CG2 
1572 C CD1 . ILE A 226 ? 0.8849 0.7169 0.9282 0.0225  0.1055  -0.1060 441 ILE A CD1 
1573 N N   . TYR A 227 ? 0.8711 0.7545 1.0513 0.1361  0.0705  0.0477  442 TYR A N   
1574 C CA  . TYR A 227 ? 0.8397 0.7561 1.0599 0.1625  0.0764  0.0842  442 TYR A CA  
1575 C C   . TYR A 227 ? 0.8318 0.7896 1.0566 0.1563  0.0628  0.0841  442 TYR A C   
1576 O O   . TYR A 227 ? 0.8305 0.7959 1.0267 0.1335  0.0394  0.0647  442 TYR A O   
1577 C CB  . TYR A 227 ? 0.8437 0.7979 1.0778 0.1719  0.0514  0.1176  442 TYR A CB  
1578 C CG  . TYR A 227 ? 0.8492 0.7685 1.0789 0.1787  0.0623  0.1243  442 TYR A CG  
1579 C CD1 . TYR A 227 ? 0.8603 0.7596 1.0563 0.1559  0.0454  0.1008  442 TYR A CD1 
1580 C CD2 . TYR A 227 ? 0.8824 0.7937 1.1432 0.2100  0.0902  0.1588  442 TYR A CD2 
1581 C CE1 . TYR A 227 ? 0.8718 0.7415 1.0636 0.1596  0.0564  0.1075  442 TYR A CE1 
1582 C CE2 . TYR A 227 ? 0.8996 0.7759 1.1546 0.2159  0.1024  0.1683  442 TYR A CE2 
1583 C CZ  . TYR A 227 ? 0.8713 0.7268 1.0911 0.1884  0.0850  0.1411  442 TYR A CZ  
1584 O OH  . TYR A 227 ? 0.8943 0.7156 1.1087 0.1928  0.0997  0.1516  442 TYR A OH  
1585 N N   . ARG A 228 ? 0.8274 0.8142 1.0903 0.1786  0.0798  0.1095  443 ARG A N   
1586 C CA  . ARG A 228 ? 0.8212 0.8609 1.0955 0.1723  0.0652  0.1171  443 ARG A CA  
1587 C C   . ARG A 228 ? 0.8063 0.9131 1.0981 0.1707  0.0329  0.1482  443 ARG A C   
1588 O O   . ARG A 228 ? 0.8001 0.9309 1.1179 0.1913  0.0346  0.1793  443 ARG A O   
1589 C CB  . ARG A 228 ? 0.8477 0.8951 1.1562 0.1952  0.1021  0.1276  443 ARG A CB  
1590 C CG  . ARG A 228 ? 0.9101 0.8900 1.1984 0.1930  0.1415  0.0937  443 ARG A CG  
1591 C CD  . ARG A 228 ? 0.9667 0.9487 1.2890 0.2183  0.1850  0.1038  443 ARG A CD  
1592 N NE  . ARG A 228 ? 0.9454 0.9998 1.3212 0.2468  0.1810  0.1507  443 ARG A NE  
1593 C CZ  . ARG A 228 ? 0.9451 1.0114 1.3616 0.2845  0.1995  0.1901  443 ARG A CZ  
1594 N NH1 . ARG A 228 ? 0.9829 0.9815 1.3908 0.2980  0.2253  0.1880  443 ARG A NH1 
1595 N NH2 . ARG A 228 ? 0.9345 1.0868 1.4016 0.3088  0.1937  0.2352  443 ARG A NH2 
1596 N N   . LEU A 229 ? 0.7896 0.9273 1.0646 0.1441  0.0061  0.1403  444 LEU A N   
1597 C CA  . LEU A 229 ? 0.8040 1.0070 1.0884 0.1315  -0.0222 0.1625  444 LEU A CA  
1598 C C   . LEU A 229 ? 0.8106 1.0875 1.1359 0.1372  -0.0172 0.1875  444 LEU A C   
1599 O O   . LEU A 229 ? 0.8186 1.0932 1.1434 0.1297  -0.0067 0.1748  444 LEU A O   
1600 C CB  . LEU A 229 ? 0.8152 1.0030 1.0544 0.0952  -0.0489 0.1388  444 LEU A CB  
1601 C CG  . LEU A 229 ? 0.8066 0.9465 1.0095 0.0877  -0.0610 0.1219  444 LEU A CG  
1602 C CD1 . LEU A 229 ? 0.8021 0.9175 0.9632 0.0592  -0.0760 0.0993  444 LEU A CD1 
1603 C CD2 . LEU A 229 ? 0.8368 1.0077 1.0485 0.0913  -0.0741 0.1432  444 LEU A CD2 
1604 N N   . VAL A 230 ? 0.8444 1.1948 1.2058 0.1503  -0.0245 0.2252  445 VAL A N   
1605 C CA  . VAL A 230 ? 0.8665 1.3085 1.2746 0.1582  -0.0211 0.2560  445 VAL A CA  
1606 C C   . VAL A 230 ? 0.8854 1.4171 1.2941 0.1287  -0.0557 0.2737  445 VAL A C   
1607 O O   . VAL A 230 ? 0.9133 1.4254 1.2859 0.1068  -0.0774 0.2618  445 VAL A O   
1608 C CB  . VAL A 230 ? 0.8431 1.3045 1.3053 0.2116  0.0123  0.2940  445 VAL A CB  
1609 C CG1 . VAL A 230 ? 0.8342 1.1934 1.2845 0.2321  0.0507  0.2680  445 VAL A CG1 
1610 C CG2 . VAL A 230 ? 0.8486 1.3400 1.3256 0.2328  0.0041  0.3299  445 VAL A CG2 
1611 N N   . ARG A 231 ? 0.8427 1.4784 1.2917 0.1253  -0.0593 0.3010  446 ARG A N   
1612 C CA  . ARG A 231 ? 0.8557 1.5936 1.3054 0.0904  -0.0912 0.3174  446 ARG A CA  
1613 C C   . ARG A 231 ? 0.8651 1.7337 1.3825 0.1212  -0.0880 0.3744  446 ARG A C   
1614 O O   . ARG A 231 ? 0.8514 1.7979 1.3807 0.1233  -0.1067 0.4070  446 ARG A O   
1615 C CB  . ARG A 231 ? 0.8657 1.6106 1.2822 0.0321  -0.1052 0.2842  446 ARG A CB  
1616 C CG  . ARG A 231 ? 0.8775 1.6474 1.2508 -0.0220 -0.1348 0.2687  446 ARG A CG  
1617 C CD  . ARG A 231 ? 0.9272 1.6541 1.2549 -0.0763 -0.1365 0.2277  446 ARG A CD  
1618 N NE  . ARG A 231 ? 0.9558 1.7944 1.3007 -0.1193 -0.1464 0.2367  446 ARG A NE  
1619 C CZ  . ARG A 231 ? 0.9756 1.8680 1.3595 -0.1152 -0.1339 0.2491  446 ARG A CZ  
1620 N NH1 . ARG A 231 ? 0.9512 1.7894 1.3568 -0.0711 -0.1094 0.2513  446 ARG A NH1 
1621 N NH2 . ARG A 231 ? 0.9553 1.9644 1.3561 -0.1593 -0.1449 0.2585  446 ARG A NH2 
1622 N N   . ASP A 232 ? 0.9550 1.8527 1.5179 0.1481  -0.0627 0.3898  447 ASP A N   
1623 C CA  . ASP A 232 ? 0.9383 1.9383 1.5576 0.1844  -0.0501 0.4425  447 ASP A CA  
1624 C C   . ASP A 232 ? 0.9253 1.8868 1.5423 0.2278  -0.0349 0.4708  447 ASP A C   
1625 O O   . ASP A 232 ? 0.8891 1.9147 1.4988 0.2210  -0.0500 0.4978  447 ASP A O   
1626 C CB  . ASP A 232 ? 0.9452 1.9417 1.6054 0.2165  -0.0132 0.4485  447 ASP A CB  
1627 C CG  . ASP A 232 ? 0.9517 2.0104 1.6201 0.1722  -0.0246 0.4295  447 ASP A CG  
1628 O OD1 . ASP A 232 ? 0.9673 2.1042 1.6176 0.1197  -0.0570 0.4261  447 ASP A OD1 
1629 O OD2 . ASP A 232 ? 0.9930 1.9953 1.6638 0.1815  0.0032  0.4086  447 ASP A OD2 
1630 N N   . ALA B 5   ? 0.8598 1.5020 1.1155 0.3526  -0.2127 -0.0268 220 ALA B N   
1631 C CA  . ALA B 5   ? 0.9162 1.4553 1.1227 0.3165  -0.1990 -0.0128 220 ALA B CA  
1632 C C   . ALA B 5   ? 0.9921 1.4180 1.1677 0.3457  -0.2028 0.0226  220 ALA B C   
1633 O O   . ALA B 5   ? 1.0007 1.3867 1.1947 0.3729  -0.1952 0.0146  220 ALA B O   
1634 C CB  . ALA B 5   ? 0.8275 1.3460 1.0429 0.2708  -0.1687 -0.0454 220 ALA B CB  
1635 N N   . ARG B 6   ? 1.1191 1.4968 1.2478 0.3364  -0.2136 0.0586  221 ARG B N   
1636 C CA  . ARG B 6   ? 1.1605 1.4291 1.2562 0.3546  -0.2192 0.0974  221 ARG B CA  
1637 C C   . ARG B 6   ? 1.1688 1.3561 1.2263 0.3107  -0.2000 0.1014  221 ARG B C   
1638 O O   . ARG B 6   ? 1.2306 1.3244 1.2620 0.3159  -0.2013 0.1291  221 ARG B O   
1639 C CB  . ARG B 6   ? 1.1995 1.4809 1.2696 0.3806  -0.2501 0.1472  221 ARG B CB  
1640 C CG  . ARG B 6   ? 1.2292 1.5553 1.3369 0.4179  -0.2659 0.1503  221 ARG B CG  
1641 C CD  . ARG B 6   ? 1.2981 1.5299 1.4222 0.4536  -0.2658 0.1604  221 ARG B CD  
1642 N NE  . ARG B 6   ? 1.3819 1.6122 1.5217 0.4888  -0.2898 0.1920  221 ARG B NE  
1643 C CZ  . ARG B 6   ? 1.3202 1.6482 1.4928 0.5090  -0.3034 0.1830  221 ARG B CZ  
1644 N NH1 . ARG B 6   ? 1.2604 1.6996 1.4555 0.4930  -0.2935 0.1412  221 ARG B NH1 
1645 N NH2 . ARG B 6   ? 1.3238 1.6365 1.5094 0.5444  -0.3284 0.2171  221 ARG B NH2 
1646 N N   . GLY B 7   ? 1.0925 1.3127 1.1486 0.2683  -0.1838 0.0743  222 GLY B N   
1647 C CA  . GLY B 7   ? 1.0121 1.1676 1.0422 0.2314  -0.1655 0.0717  222 GLY B CA  
1648 C C   . GLY B 7   ? 0.9079 1.0965 0.9593 0.2002  -0.1471 0.0317  222 GLY B C   
1649 O O   . GLY B 7   ? 0.8894 1.1420 0.9757 0.2044  -0.1463 0.0071  222 GLY B O   
1650 N N   . LEU B 8   ? 0.8663 1.0147 0.8999 0.1684  -0.1334 0.0260  223 LEU B N   
1651 C CA  . LEU B 8   ? 0.8441 1.0170 0.8963 0.1393  -0.1201 -0.0059 223 LEU B CA  
1652 C C   . LEU B 8   ? 0.8190 1.0561 0.8724 0.1255  -0.1286 -0.0186 223 LEU B C   
1653 O O   . LEU B 8   ? 0.7973 1.0256 0.8274 0.1114  -0.1286 -0.0150 223 LEU B O   
1654 C CB  . LEU B 8   ? 0.8382 0.9467 0.8742 0.1167  -0.1057 -0.0065 223 LEU B CB  
1655 C CG  . LEU B 8   ? 0.8171 0.9221 0.8737 0.0958  -0.0911 -0.0294 223 LEU B CG  
1656 C CD1 . LEU B 8   ? 0.8227 0.8684 0.8603 0.0794  -0.0820 -0.0238 223 LEU B CD1 
1657 C CD2 . LEU B 8   ? 0.7686 0.9257 0.8475 0.0777  -0.0928 -0.0528 223 LEU B CD2 
1658 N N   . GLY B 9   ? 0.7629 1.0733 0.8451 0.1280  -0.1352 -0.0383 224 GLY B N   
1659 C CA  . GLY B 9   ? 0.7372 1.1111 0.8224 0.1103  -0.1425 -0.0604 224 GLY B CA  
1660 C C   . GLY B 9   ? 0.7224 1.1894 0.8335 0.1219  -0.1572 -0.0722 224 GLY B C   
1661 O O   . GLY B 9   ? 0.7283 1.2138 0.8500 0.1529  -0.1660 -0.0547 224 GLY B O   
1662 N N   . THR B 10  ? 0.7077 1.2364 0.8329 0.0974  -0.1605 -0.1065 225 THR B N   
1663 C CA  . THR B 10  ? 0.6962 1.3292 0.8466 0.1033  -0.1765 -0.1224 225 THR B CA  
1664 C C   . THR B 10  ? 0.7103 1.4044 0.8300 0.1099  -0.1957 -0.1160 225 THR B C   
1665 O O   . THR B 10  ? 0.7326 1.3883 0.8121 0.1104  -0.1945 -0.0963 225 THR B O   
1666 C CB  . THR B 10  ? 0.6883 1.3624 0.8803 0.0656  -0.1685 -0.1700 225 THR B CB  
1667 O OG1 . THR B 10  ? 0.6889 1.3707 0.8721 0.0362  -0.1688 -0.2026 225 THR B OG1 
1668 C CG2 . THR B 10  ? 0.6649 1.2713 0.8771 0.0481  -0.1464 -0.1728 225 THR B CG2 
1669 N N   . ALA B 11  ? 0.6958 1.4970 0.8342 0.1114  -0.2130 -0.1344 226 ALA B N   
1670 C CA  . ALA B 11  ? 0.6981 1.5489 0.8010 0.1128  -0.2233 -0.1264 226 ALA B CA  
1671 C C   . ALA B 11  ? 0.7244 1.5839 0.8155 0.0764  -0.2132 -0.1689 226 ALA B C   
1672 O O   . ALA B 11  ? 0.7572 1.6501 0.8123 0.0759  -0.2162 -0.1622 226 ALA B O   
1673 C CB  . ALA B 11  ? 0.7270 1.6571 0.8492 0.1236  -0.2332 -0.1293 226 ALA B CB  
1674 N N   . ARG B 12  ? 0.7048 1.5321 0.8264 0.0468  -0.2006 -0.2122 227 ARG B N   
1675 C CA  . ARG B 12  ? 0.6972 1.5172 0.8147 0.0171  -0.1902 -0.2577 227 ARG B CA  
1676 C C   . ARG B 12  ? 0.7147 1.4546 0.8167 0.0147  -0.1804 -0.2550 227 ARG B C   
1677 O O   . ARG B 12  ? 0.6950 1.4309 0.7919 -0.0014 -0.1738 -0.2921 227 ARG B O   
1678 C CB  . ARG B 12  ? 0.7202 1.5415 0.8841 -0.0170 -0.1816 -0.3083 227 ARG B CB  
1679 C CG  . ARG B 12  ? 0.7173 1.5985 0.9099 -0.0165 -0.1867 -0.3058 227 ARG B CG  
1680 C CD  . ARG B 12  ? 0.7402 1.6200 0.9742 -0.0582 -0.1763 -0.3539 227 ARG B CD  
1681 N NE  . ARG B 12  ? 0.7689 1.6353 0.9951 -0.0799 -0.1701 -0.3964 227 ARG B NE  
1682 C CZ  . ARG B 12  ? 0.8032 1.6297 1.0600 -0.1164 -0.1601 -0.4386 227 ARG B CZ  
1683 N NH1 . ARG B 12  ? 0.8072 1.6032 1.1008 -0.1423 -0.1537 -0.4406 227 ARG B NH1 
1684 N NH2 . ARG B 12  ? 0.8164 1.6319 1.0671 -0.1275 -0.1553 -0.4781 227 ARG B NH2 
1685 N N   . LEU B 13  ? 0.7214 1.3800 0.8173 0.0312  -0.1714 -0.2113 228 LEU B N   
1686 C CA  . LEU B 13  ? 0.7437 1.3130 0.8238 0.0295  -0.1558 -0.2010 228 LEU B CA  
1687 C C   . LEU B 13  ? 0.7356 1.2460 0.7988 0.0523  -0.1530 -0.1466 228 LEU B C   
1688 O O   . LEU B 13  ? 0.7442 1.2376 0.8289 0.0600  -0.1518 -0.1350 228 LEU B O   
1689 C CB  . LEU B 13  ? 0.7360 1.2411 0.8496 0.0061  -0.1418 -0.2351 228 LEU B CB  
1690 C CG  . LEU B 13  ? 0.7368 1.1687 0.8362 0.0078  -0.1299 -0.2306 228 LEU B CG  
1691 C CD1 . LEU B 13  ? 0.7467 1.2308 0.8296 0.0059  -0.1326 -0.2624 228 LEU B CD1 
1692 C CD2 . LEU B 13  ? 0.7302 1.0833 0.8603 -0.0085 -0.1191 -0.2469 228 LEU B CD2 
1693 N N   . GLN B 14  ? 0.7042 1.1880 0.7308 0.0609  -0.1512 -0.1171 229 GLN B N   
1694 C CA  . GLN B 14  ? 0.7302 1.1516 0.7383 0.0788  -0.1494 -0.0686 229 GLN B CA  
1695 C C   . GLN B 14  ? 0.7525 1.1041 0.7485 0.0684  -0.1344 -0.0642 229 GLN B C   
1696 O O   . GLN B 14  ? 0.7359 1.1080 0.7213 0.0565  -0.1300 -0.0825 229 GLN B O   
1697 C CB  . GLN B 14  ? 0.7492 1.2076 0.7222 0.0973  -0.1657 -0.0265 229 GLN B CB  
1698 C CG  . GLN B 14  ? 0.8033 1.1899 0.7445 0.1041  -0.1622 0.0208  229 GLN B CG  
1699 C CD  . GLN B 14  ? 0.8510 1.2392 0.7721 0.1302  -0.1806 0.0700  229 GLN B CD  
1700 O OE1 . GLN B 14  ? 0.9514 1.3231 0.8959 0.1547  -0.1876 0.0766  229 GLN B OE1 
1701 N NE2 . GLN B 14  ? 0.9113 1.3233 0.7898 0.1261  -0.1891 0.1055  229 GLN B NE2 
1702 N N   . LEU B 15  ? 0.7506 1.0292 0.7509 0.0737  -0.1265 -0.0450 230 LEU B N   
1703 C CA  . LEU B 15  ? 0.7910 1.0103 0.7782 0.0655  -0.1152 -0.0355 230 LEU B CA  
1704 C C   . LEU B 15  ? 0.8272 1.0377 0.7774 0.0699  -0.1194 0.0043  230 LEU B C   
1705 O O   . LEU B 15  ? 0.8448 1.0463 0.7836 0.0858  -0.1291 0.0349  230 LEU B O   
1706 C CB  . LEU B 15  ? 0.8066 0.9596 0.8089 0.0660  -0.1060 -0.0319 230 LEU B CB  
1707 C CG  . LEU B 15  ? 0.8071 0.9065 0.7973 0.0573  -0.0968 -0.0232 230 LEU B CG  
1708 C CD1 . LEU B 15  ? 0.7799 0.8750 0.7909 0.0456  -0.0909 -0.0527 230 LEU B CD1 
1709 C CD2 . LEU B 15  ? 0.8297 0.8704 0.8160 0.0624  -0.0919 -0.0046 230 LEU B CD2 
1710 N N   . VAL B 16  ? 0.7889 1.0036 0.7225 0.0558  -0.1126 0.0041  231 VAL B N   
1711 C CA  . VAL B 16  ? 0.8623 1.0725 0.7597 0.0499  -0.1142 0.0430  231 VAL B CA  
1712 C C   . VAL B 16  ? 0.8559 1.0027 0.7492 0.0385  -0.1038 0.0551  231 VAL B C   
1713 O O   . VAL B 16  ? 0.9038 1.0068 0.7756 0.0353  -0.1061 0.0913  231 VAL B O   
1714 C CB  . VAL B 16  ? 0.8371 1.1295 0.7147 0.0375  -0.1140 0.0345  231 VAL B CB  
1715 C CG1 . VAL B 16  ? 0.8663 1.1526 0.7110 0.0193  -0.1083 0.0694  231 VAL B CG1 
1716 C CG2 . VAL B 16  ? 0.8324 1.1896 0.6990 0.0477  -0.1291 0.0399  231 VAL B CG2 
1717 N N   . GLU B 17  ? 0.8196 0.9606 0.7341 0.0321  -0.0943 0.0250  232 GLU B N   
1718 C CA  . GLU B 17  ? 0.8277 0.9230 0.7410 0.0215  -0.0866 0.0327  232 GLU B CA  
1719 C C   . GLU B 17  ? 0.8043 0.8765 0.7478 0.0266  -0.0824 0.0040  232 GLU B C   
1720 O O   . GLU B 17  ? 0.7505 0.8529 0.7150 0.0307  -0.0821 -0.0265 232 GLU B O   
1721 C CB  . GLU B 17  ? 0.7924 0.9294 0.6916 0.0032  -0.0803 0.0361  232 GLU B CB  
1722 C CG  . GLU B 17  ? 0.8368 0.9333 0.7356 -0.0109 -0.0743 0.0460  232 GLU B CG  
1723 C CD  . GLU B 17  ? 0.9428 1.0278 0.8099 -0.0338 -0.0735 0.0845  232 GLU B CD  
1724 O OE1 . GLU B 17  ? 0.9437 1.0239 0.7881 -0.0321 -0.0804 0.1121  232 GLU B OE1 
1725 O OE2 . GLU B 17  ? 0.9800 1.0596 0.8455 -0.0544 -0.0676 0.0891  232 GLU B OE2 
1726 N N   . PHE B 18  ? 0.7818 0.7990 0.7259 0.0251  -0.0799 0.0142  233 PHE B N   
1727 C CA  . PHE B 18  ? 0.7876 0.7819 0.7521 0.0262  -0.0768 -0.0023 233 PHE B CA  
1728 C C   . PHE B 18  ? 0.7934 0.7564 0.7463 0.0162  -0.0742 0.0116  233 PHE B C   
1729 O O   . PHE B 18  ? 0.7985 0.7280 0.7339 0.0122  -0.0741 0.0291  233 PHE B O   
1730 C CB  . PHE B 18  ? 0.7893 0.7595 0.7673 0.0336  -0.0769 -0.0080 233 PHE B CB  
1731 C CG  . PHE B 18  ? 0.7934 0.7380 0.7857 0.0307  -0.0744 -0.0156 233 PHE B CG  
1732 C CD1 . PHE B 18  ? 0.7739 0.7271 0.7888 0.0321  -0.0763 -0.0347 233 PHE B CD1 
1733 C CD2 . PHE B 18  ? 0.7860 0.6970 0.7675 0.0266  -0.0715 -0.0033 233 PHE B CD2 
1734 C CE1 . PHE B 18  ? 0.7856 0.7083 0.8114 0.0306  -0.0770 -0.0333 233 PHE B CE1 
1735 C CE2 . PHE B 18  ? 0.7873 0.6812 0.7762 0.0232  -0.0713 -0.0038 233 PHE B CE2 
1736 C CZ  . PHE B 18  ? 0.7924 0.6891 0.8028 0.0256  -0.0748 -0.0146 233 PHE B CZ  
1737 N N   . SER B 19  ? 0.7570 0.7309 0.7218 0.0135  -0.0735 0.0015  234 SER B N   
1738 C CA  . SER B 19  ? 0.8063 0.7611 0.7618 0.0022  -0.0730 0.0117  234 SER B CA  
1739 C C   . SER B 19  ? 0.7699 0.7316 0.7454 0.0092  -0.0765 0.0005  234 SER B C   
1740 O O   . SER B 19  ? 0.7095 0.6897 0.7075 0.0224  -0.0789 -0.0156 234 SER B O   
1741 C CB  . SER B 19  ? 0.8075 0.7869 0.7480 -0.0163 -0.0707 0.0229  234 SER B CB  
1742 O OG  . SER B 19  ? 0.7273 0.7674 0.6823 -0.0145 -0.0692 0.0089  234 SER B OG  
1743 N N   . ALA B 20  ? 0.7761 0.7201 0.7431 0.0013  -0.0783 0.0087  235 ALA B N   
1744 C CA  . ALA B 20  ? 0.7794 0.7322 0.7599 0.0078  -0.0853 0.0067  235 ALA B CA  
1745 C C   . ALA B 20  ? 0.7460 0.7204 0.7162 -0.0092 -0.0869 0.0112  235 ALA B C   
1746 O O   . ALA B 20  ? 0.7577 0.7084 0.7052 -0.0271 -0.0830 0.0175  235 ALA B O   
1747 C CB  . ALA B 20  ? 0.7877 0.7031 0.7630 0.0115  -0.0873 0.0146  235 ALA B CB  
1748 N N   . PHE B 21  ? 0.6419 0.6632 0.6321 -0.0037 -0.0930 0.0047  236 PHE B N   
1749 C CA  . PHE B 21  ? 0.7289 0.7903 0.7149 -0.0256 -0.0928 0.0050  236 PHE B CA  
1750 C C   . PHE B 21  ? 0.6857 0.7969 0.6968 -0.0119 -0.1044 -0.0008 236 PHE B C   
1751 O O   . PHE B 21  ? 0.6701 0.7833 0.7050 0.0178  -0.1119 -0.0056 236 PHE B O   
1752 C CB  . PHE B 21  ? 0.8021 0.9008 0.7883 -0.0400 -0.0834 0.0019  236 PHE B CB  
1753 C CG  . PHE B 21  ? 0.6996 0.8491 0.7140 -0.0174 -0.0824 -0.0158 236 PHE B CG  
1754 C CD1 . PHE B 21  ? 0.6946 0.9160 0.7380 -0.0090 -0.0857 -0.0310 236 PHE B CD1 
1755 C CD2 . PHE B 21  ? 0.7504 0.8823 0.7644 -0.0039 -0.0785 -0.0221 236 PHE B CD2 
1756 C CE1 . PHE B 21  ? 0.7235 0.9926 0.7956 0.0155  -0.0839 -0.0554 236 PHE B CE1 
1757 C CE2 . PHE B 21  ? 0.7078 0.8863 0.7470 0.0158  -0.0773 -0.0464 236 PHE B CE2 
1758 C CZ  . PHE B 21  ? 0.6777 0.9223 0.7463 0.0269  -0.0793 -0.0647 236 PHE B CZ  
1759 N N   . VAL B 22  ? 0.7556 0.9077 0.7641 -0.0338 -0.1071 -0.0010 237 VAL B N   
1760 C CA  . VAL B 22  ? 0.7971 1.0195 0.8347 -0.0211 -0.1192 -0.0082 237 VAL B CA  
1761 C C   . VAL B 22  ? 0.7267 1.0225 0.7748 -0.0481 -0.1118 -0.0182 237 VAL B C   
1762 O O   . VAL B 22  ? 0.6721 0.9523 0.6951 -0.0876 -0.1027 -0.0124 237 VAL B O   
1763 C CB  . VAL B 22  ? 0.7436 0.9650 0.7697 -0.0241 -0.1335 0.0013  237 VAL B CB  
1764 C CG1 . VAL B 22  ? 0.7466 0.9517 0.7404 -0.0669 -0.1271 0.0011  237 VAL B CG1 
1765 C CG2 . VAL B 22  ? 0.7262 1.0306 0.7862 -0.0066 -0.1495 -0.0042 237 VAL B CG2 
1766 N N   . GLU B 23  ? 0.7084 1.0846 0.7953 -0.0274 -0.1156 -0.0337 238 GLU B N   
1767 C CA  . GLU B 23  ? 0.7407 1.2093 0.8429 -0.0548 -0.1082 -0.0446 238 GLU B CA  
1768 C C   . GLU B 23  ? 0.6986 1.2425 0.8296 -0.0462 -0.1247 -0.0518 238 GLU B C   
1769 O O   . GLU B 23  ? 0.6848 1.2501 0.8480 0.0011  -0.1396 -0.0585 238 GLU B O   
1770 C CB  . GLU B 23  ? 0.6776 1.2051 0.8044 -0.0392 -0.0965 -0.0635 238 GLU B CB  
1771 C CG  . GLU B 23  ? 0.7074 1.1831 0.8032 -0.0535 -0.0810 -0.0553 238 GLU B CG  
1772 C CD  . GLU B 23  ? 0.6592 1.1817 0.7780 -0.0249 -0.0736 -0.0798 238 GLU B CD  
1773 O OE1 . GLU B 23  ? 0.5993 1.1781 0.7615 0.0127  -0.0808 -0.1061 238 GLU B OE1 
1774 O OE2 . GLU B 23  ? 0.6721 1.1760 0.7661 -0.0378 -0.0619 -0.0746 238 GLU B OE2 
1775 N N   . PRO B 24  ? 0.7291 1.3129 0.8512 -0.0899 -0.1249 -0.0503 239 PRO B N   
1776 C CA  . PRO B 24  ? 0.7388 1.4014 0.8871 -0.0817 -0.1440 -0.0571 239 PRO B CA  
1777 C C   . PRO B 24  ? 0.7311 1.5151 0.9351 -0.0551 -0.1461 -0.0786 239 PRO B C   
1778 O O   . PRO B 24  ? 0.7248 1.5514 0.9400 -0.0665 -0.1275 -0.0909 239 PRO B O   
1779 C CB  . PRO B 24  ? 0.7723 1.4486 0.8969 -0.1456 -0.1398 -0.0566 239 PRO B CB  
1780 C CG  . PRO B 24  ? 0.7767 1.4270 0.8834 -0.1848 -0.1155 -0.0528 239 PRO B CG  
1781 C CD  . PRO B 24  ? 0.7433 1.3091 0.8353 -0.1496 -0.1087 -0.0436 239 PRO B CD  
1782 N N   . PRO B 25  ? 0.7053 1.5534 0.9453 -0.0172 -0.1691 -0.0838 240 PRO B N   
1783 C CA  . PRO B 25  ? 0.6661 1.6316 0.9676 0.0207  -0.1726 -0.1095 240 PRO B CA  
1784 C C   . PRO B 25  ? 0.6695 1.7315 0.9805 -0.0253 -0.1497 -0.1268 240 PRO B C   
1785 O O   . PRO B 25  ? 0.6570 1.7871 1.0009 0.0001  -0.1381 -0.1500 240 PRO B O   
1786 C CB  . PRO B 25  ? 0.6370 1.6286 0.9612 0.0623  -0.2006 -0.1025 240 PRO B CB  
1787 C CG  . PRO B 25  ? 0.6831 1.6024 0.9620 0.0434  -0.2169 -0.0746 240 PRO B CG  
1788 C CD  . PRO B 25  ? 0.7082 1.5465 0.9342 -0.0152 -0.1926 -0.0686 240 PRO B CD  
1789 N N   . ASP B 26  ? 0.6682 1.7262 0.9459 -0.0929 -0.1404 -0.1165 241 ASP B N   
1790 C CA  . ASP B 26  ? 0.6692 1.7985 0.9455 -0.1446 -0.1159 -0.1254 241 ASP B CA  
1791 C C   . ASP B 26  ? 0.7185 1.8144 0.9674 -0.1859 -0.0932 -0.1164 241 ASP B C   
1792 O O   . ASP B 26  ? 0.7212 1.8445 0.9514 -0.2452 -0.0740 -0.1108 241 ASP B O   
1793 C CB  . ASP B 26  ? 0.6686 1.8078 0.9255 -0.1975 -0.1184 -0.1197 241 ASP B CB  
1794 C CG  . ASP B 26  ? 0.7361 1.7707 0.9533 -0.2194 -0.1319 -0.1028 241 ASP B CG  
1795 O OD1 . ASP B 26  ? 0.7936 1.7525 0.9787 -0.2548 -0.1213 -0.0908 241 ASP B OD1 
1796 O OD2 . ASP B 26  ? 0.7244 1.7506 0.9399 -0.1985 -0.1535 -0.1010 241 ASP B OD2 
1797 N N   . ALA B 27  ? 0.7760 1.8005 1.0152 -0.1553 -0.0941 -0.1111 242 ALA B N   
1798 C CA  . ALA B 27  ? 0.7977 1.7835 1.0046 -0.1833 -0.0707 -0.1002 242 ALA B CA  
1799 C C   . ALA B 27  ? 0.7774 1.8942 1.0172 -0.1810 -0.0533 -0.1234 242 ALA B C   
1800 O O   . ALA B 27  ? 0.7548 1.8714 0.9658 -0.2170 -0.0326 -0.1114 242 ALA B O   
1801 C CB  . ALA B 27  ? 0.7669 1.6242 0.9457 -0.1450 -0.0732 -0.0892 242 ALA B CB  
1802 N N   . VAL B 28  ? 0.7525 1.9462 1.0333 -0.1330 -0.0575 -0.1522 243 VAL B N   
1803 C CA  . VAL B 28  ? 0.7139 2.0081 1.0098 -0.1234 -0.0373 -0.1791 243 VAL B CA  
1804 C C   . VAL B 28  ? 0.7313 2.0938 1.0046 -0.1910 -0.0186 -0.1697 243 VAL B C   
1805 O O   . VAL B 28  ? 0.7345 2.1621 0.9930 -0.2130 0.0027  -0.1768 243 VAL B O   
1806 C CB  . VAL B 28  ? 0.6740 2.0176 1.0197 -0.0511 -0.0508 -0.2136 243 VAL B CB  
1807 C CG1 . VAL B 28  ? 0.6875 2.1101 1.0469 -0.0260 -0.0333 -0.2505 243 VAL B CG1 
1808 C CG2 . VAL B 28  ? 0.7265 1.9787 1.0901 0.0069  -0.0764 -0.2107 243 VAL B CG2 
1809 N N   . ASP B 29  ? 0.6613 2.0124 0.9289 -0.2254 -0.0275 -0.1554 244 ASP B N   
1810 C CA  . ASP B 29  ? 0.6774 2.0723 0.9196 -0.2970 -0.0120 -0.1434 244 ASP B CA  
1811 C C   . ASP B 29  ? 0.7247 2.0344 0.9165 -0.3598 -0.0011 -0.1067 244 ASP B C   
1812 O O   . ASP B 29  ? 0.7390 2.0802 0.9048 -0.3942 0.0179  -0.0961 244 ASP B O   
1813 C CB  . ASP B 29  ? 0.6951 2.1003 0.9478 -0.3125 -0.0262 -0.1446 244 ASP B CB  
1814 C CG  . ASP B 29  ? 0.6709 2.1437 0.9728 -0.2446 -0.0430 -0.1730 244 ASP B CG  
1815 O OD1 . ASP B 29  ? 0.6342 2.1681 0.9635 -0.1956 -0.0383 -0.1977 244 ASP B OD1 
1816 O OD2 . ASP B 29  ? 0.6775 2.1413 0.9889 -0.2401 -0.0620 -0.1711 244 ASP B OD2 
1817 N N   . SER B 30  ? 0.7600 1.9583 0.9342 -0.3746 -0.0148 -0.0860 245 SER B N   
1818 C CA  . SER B 30  ? 0.7943 1.8920 0.9221 -0.4266 -0.0075 -0.0503 245 SER B CA  
1819 C C   . SER B 30  ? 0.7702 1.7786 0.8976 -0.3896 -0.0213 -0.0442 245 SER B C   
1820 O O   . SER B 30  ? 0.7946 1.7333 0.9218 -0.3646 -0.0404 -0.0485 245 SER B O   
1821 C CB  . SER B 30  ? 0.8275 1.8625 0.9278 -0.4886 -0.0101 -0.0340 245 SER B CB  
1822 O OG  . SER B 30  ? 0.9186 1.8920 0.9743 -0.5448 0.0037  0.0004  245 SER B OG  
1823 N N   . TYR B 31  ? 0.7627 1.7450 0.8701 -0.3718 -0.0101 -0.0338 246 TYR B N   
1824 C CA  . TYR B 31  ? 0.7514 1.6173 0.8396 -0.3176 -0.0199 -0.0299 246 TYR B CA  
1825 C C   . TYR B 31  ? 0.7696 1.4874 0.8164 -0.3381 -0.0285 -0.0035 246 TYR B C   
1826 O O   . TYR B 31  ? 0.8133 1.4942 0.8339 -0.3975 -0.0228 0.0191  246 TYR B O   
1827 C CB  . TYR B 31  ? 0.7247 1.5947 0.7936 -0.3055 -0.0059 -0.0230 246 TYR B CB  
1828 C CG  . TYR B 31  ? 0.7105 1.4680 0.7615 -0.2559 -0.0155 -0.0201 246 TYR B CG  
1829 C CD1 . TYR B 31  ? 0.6977 1.4562 0.7821 -0.1933 -0.0277 -0.0497 246 TYR B CD1 
1830 C CD2 . TYR B 31  ? 0.7418 1.3926 0.7452 -0.2720 -0.0135 0.0133  246 TYR B CD2 
1831 C CE1 . TYR B 31  ? 0.6912 1.3524 0.7615 -0.1550 -0.0353 -0.0474 246 TYR B CE1 
1832 C CE2 . TYR B 31  ? 0.7498 1.3128 0.7419 -0.2286 -0.0220 0.0131  246 TYR B CE2 
1833 C CZ  . TYR B 31  ? 0.7153 1.2863 0.7408 -0.1736 -0.0317 -0.0180 246 TYR B CZ  
1834 O OH  . TYR B 31  ? 0.7194 1.2093 0.7367 -0.1364 -0.0391 -0.0192 246 TYR B OH  
1835 N N   . GLN B 32  ? 0.7379 1.3702 0.7804 -0.2883 -0.0419 -0.0082 247 GLN B N   
1836 C CA  . GLN B 32  ? 0.7633 1.2587 0.7685 -0.2938 -0.0483 0.0106  247 GLN B CA  
1837 C C   . GLN B 32  ? 0.7271 1.1720 0.7387 -0.2322 -0.0598 0.0001  247 GLN B C   
1838 O O   . GLN B 32  ? 0.7140 1.2201 0.7600 -0.1925 -0.0670 -0.0203 247 GLN B O   
1839 C CB  . GLN B 32  ? 0.7835 1.2561 0.7831 -0.3342 -0.0557 0.0087  247 GLN B CB  
1840 C CG  . GLN B 32  ? 0.7775 1.2920 0.8043 -0.3038 -0.0723 -0.0150 247 GLN B CG  
1841 C CD  . GLN B 32  ? 0.8268 1.3430 0.8487 -0.3490 -0.0799 -0.0231 247 GLN B CD  
1842 O OE1 . GLN B 32  ? 0.8059 1.3586 0.8431 -0.3311 -0.0956 -0.0392 247 GLN B OE1 
1843 N NE2 . GLN B 32  ? 0.8424 1.3221 0.8430 -0.4102 -0.0700 -0.0116 247 GLN B NE2 
1844 N N   . ARG B 33  ? 0.7287 1.0623 0.7095 -0.2244 -0.0618 0.0144  248 ARG B N   
1845 C CA  . ARG B 33  ? 0.7259 1.0144 0.7120 -0.1751 -0.0717 0.0064  248 ARG B CA  
1846 C C   . ARG B 33  ? 0.7336 0.9182 0.6890 -0.1818 -0.0751 0.0161  248 ARG B C   
1847 O O   . ARG B 33  ? 0.7588 0.8853 0.6884 -0.2075 -0.0688 0.0314  248 ARG B O   
1848 C CB  . ARG B 33  ? 0.7076 0.9969 0.7000 -0.1398 -0.0672 0.0039  248 ARG B CB  
1849 C CG  . ARG B 33  ? 0.7062 0.9294 0.6669 -0.1475 -0.0601 0.0234  248 ARG B CG  
1850 C CD  . ARG B 33  ? 0.7273 1.0028 0.6959 -0.1317 -0.0531 0.0171  248 ARG B CD  
1851 N NE  . ARG B 33  ? 0.7772 0.9979 0.7341 -0.1058 -0.0547 0.0203  248 ARG B NE  
1852 C CZ  . ARG B 33  ? 0.7944 1.0562 0.7590 -0.0869 -0.0511 0.0072  248 ARG B CZ  
1853 N NH1 . ARG B 33  ? 0.7256 1.0820 0.7075 -0.0891 -0.0439 -0.0107 248 ARG B NH1 
1854 N NH2 . ARG B 33  ? 0.7713 0.9866 0.7273 -0.0667 -0.0542 0.0083  248 ARG B NH2 
1855 N N   . HIS B 34  ? 0.7685 0.9328 0.7269 -0.1581 -0.0854 0.0077  249 HIS B N   
1856 C CA  . HIS B 34  ? 0.7744 0.8547 0.7063 -0.1585 -0.0869 0.0100  249 HIS B CA  
1857 C C   . HIS B 34  ? 0.7796 0.8151 0.7090 -0.1222 -0.0850 0.0153  249 HIS B C   
1858 O O   . HIS B 34  ? 0.7643 0.8258 0.7131 -0.0916 -0.0897 0.0119  249 HIS B O   
1859 C CB  . HIS B 34  ? 0.8035 0.8996 0.7343 -0.1589 -0.0982 -0.0013 249 HIS B CB  
1860 C CG  . HIS B 34  ? 0.8291 0.8554 0.7340 -0.1541 -0.0980 -0.0046 249 HIS B CG  
1861 N ND1 . HIS B 34  ? 0.8646 0.8429 0.7473 -0.1836 -0.0946 -0.0147 249 HIS B ND1 
1862 C CD2 . HIS B 34  ? 0.8461 0.8463 0.7452 -0.1243 -0.0998 -0.0018 249 HIS B CD2 
1863 C CE1 . HIS B 34  ? 0.9048 0.8383 0.7704 -0.1681 -0.0936 -0.0220 249 HIS B CE1 
1864 N NE2 . HIS B 34  ? 0.8804 0.8300 0.7545 -0.1346 -0.0959 -0.0120 249 HIS B NE2 
1865 N N   . LEU B 35  ? 0.7370 0.7048 0.6455 -0.1257 -0.0792 0.0228  250 LEU B N   
1866 C CA  . LEU B 35  ? 0.8066 0.7372 0.7135 -0.0959 -0.0772 0.0261  250 LEU B CA  
1867 C C   . LEU B 35  ? 0.8603 0.7542 0.7570 -0.0864 -0.0793 0.0181  250 LEU B C   
1868 O O   . LEU B 35  ? 0.8416 0.6961 0.7208 -0.1014 -0.0776 0.0120  250 LEU B O   
1869 C CB  . LEU B 35  ? 0.8446 0.7351 0.7374 -0.1008 -0.0718 0.0399  250 LEU B CB  
1870 C CG  . LEU B 35  ? 0.8150 0.7444 0.7088 -0.1127 -0.0681 0.0533  250 LEU B CG  
1871 C CD1 . LEU B 35  ? 0.8421 0.7184 0.7146 -0.1182 -0.0669 0.0745  250 LEU B CD1 
1872 C CD2 . LEU B 35  ? 0.7981 0.7779 0.7116 -0.0864 -0.0680 0.0443  250 LEU B CD2 
1873 N N   . PHE B 36  ? 0.8075 0.7153 0.7149 -0.0634 -0.0826 0.0171  251 PHE B N   
1874 C CA  . PHE B 36  ? 0.8518 0.7338 0.7470 -0.0558 -0.0817 0.0136  251 PHE B CA  
1875 C C   . PHE B 36  ? 0.8494 0.6895 0.7392 -0.0455 -0.0735 0.0122  251 PHE B C   
1876 O O   . PHE B 36  ? 0.8408 0.6519 0.7157 -0.0488 -0.0692 0.0022  251 PHE B O   
1877 C CB  . PHE B 36  ? 0.8094 0.7133 0.7169 -0.0384 -0.0879 0.0206  251 PHE B CB  
1878 C CG  . PHE B 36  ? 0.8013 0.7504 0.7197 -0.0390 -0.0996 0.0236  251 PHE B CG  
1879 C CD1 . PHE B 36  ? 0.8082 0.7789 0.7110 -0.0554 -0.1058 0.0203  251 PHE B CD1 
1880 C CD2 . PHE B 36  ? 0.7834 0.7586 0.7298 -0.0207 -0.1055 0.0260  251 PHE B CD2 
1881 C CE1 . PHE B 36  ? 0.7993 0.8231 0.7155 -0.0531 -0.1193 0.0235  251 PHE B CE1 
1882 C CE2 . PHE B 36  ? 0.7861 0.8091 0.7488 -0.0143 -0.1181 0.0271  251 PHE B CE2 
1883 C CZ  . PHE B 36  ? 0.8041 0.8542 0.7521 -0.0301 -0.1258 0.0282  251 PHE B CZ  
1884 N N   . VAL B 37  ? 0.8198 0.6630 0.7238 -0.0312 -0.0720 0.0182  252 VAL B N   
1885 C CA  . VAL B 37  ? 0.8193 0.6359 0.7224 -0.0193 -0.0672 0.0183  252 VAL B CA  
1886 C C   . VAL B 37  ? 0.8044 0.6334 0.7138 -0.0163 -0.0689 0.0274  252 VAL B C   
1887 O O   . VAL B 37  ? 0.8071 0.6725 0.7280 -0.0171 -0.0710 0.0274  252 VAL B O   
1888 C CB  . VAL B 37  ? 0.7876 0.6102 0.7006 -0.0051 -0.0639 0.0141  252 VAL B CB  
1889 C CG1 . VAL B 37  ? 0.8318 0.6539 0.7321 -0.0121 -0.0614 0.0089  252 VAL B CG1 
1890 C CG2 . VAL B 37  ? 0.8040 0.6519 0.7362 0.0005  -0.0678 0.0171  252 VAL B CG2 
1891 N N   . HIS B 38  ? 0.8192 0.6221 0.7212 -0.0106 -0.0686 0.0347  253 HIS B N   
1892 C CA  . HIS B 38  ? 0.8630 0.6841 0.7634 -0.0106 -0.0714 0.0487  253 HIS B CA  
1893 C C   . HIS B 38  ? 0.8726 0.6814 0.7742 0.0100  -0.0743 0.0548  253 HIS B C   
1894 O O   . HIS B 38  ? 0.8808 0.6464 0.7772 0.0189  -0.0752 0.0564  253 HIS B O   
1895 C CB  . HIS B 38  ? 0.8444 0.6502 0.7270 -0.0348 -0.0721 0.0650  253 HIS B CB  
1896 C CG  . HIS B 38  ? 0.8731 0.7137 0.7489 -0.0411 -0.0734 0.0828  253 HIS B CG  
1897 N ND1 . HIS B 38  ? 0.9034 0.7167 0.7578 -0.0568 -0.0758 0.1104  253 HIS B ND1 
1898 C CD2 . HIS B 38  ? 0.8818 0.7846 0.7674 -0.0356 -0.0725 0.0765  253 HIS B CD2 
1899 C CE1 . HIS B 38  ? 0.9221 0.7880 0.7696 -0.0622 -0.0757 0.1238  253 HIS B CE1 
1900 N NE2 . HIS B 38  ? 0.8921 0.8160 0.7592 -0.0485 -0.0732 0.0993  253 HIS B NE2 
1901 N N   . ILE B 39  ? 0.8325 0.6831 0.7430 0.0195  -0.0769 0.0550  254 ILE B N   
1902 C CA  . ILE B 39  ? 0.8816 0.7342 0.7917 0.0380  -0.0833 0.0652  254 ILE B CA  
1903 C C   . ILE B 39  ? 0.9089 0.8004 0.8062 0.0311  -0.0881 0.0815  254 ILE B C   
1904 O O   . ILE B 39  ? 0.8531 0.7928 0.7565 0.0224  -0.0850 0.0684  254 ILE B O   
1905 C CB  . ILE B 39  ? 0.8688 0.7501 0.8025 0.0552  -0.0830 0.0464  254 ILE B CB  
1906 C CG1 . ILE B 39  ? 0.8562 0.7138 0.7997 0.0570  -0.0754 0.0310  254 ILE B CG1 
1907 C CG2 . ILE B 39  ? 0.8627 0.7549 0.7988 0.0772  -0.0921 0.0570  254 ILE B CG2 
1908 C CD1 . ILE B 39  ? 0.8181 0.7096 0.7853 0.0660  -0.0730 0.0150  254 ILE B CD1 
1909 N N   . SER B 40  ? 0.9469 0.8198 0.8266 0.0364  -0.0961 0.1095  255 SER B N   
1910 C CA  . SER B 40  ? 0.9874 0.9055 0.8482 0.0276  -0.1010 0.1303  255 SER B CA  
1911 C C   . SER B 40  ? 1.0436 0.9545 0.8966 0.0509  -0.1150 0.1552  255 SER B C   
1912 O O   . SER B 40  ? 1.0656 0.9096 0.9146 0.0630  -0.1211 0.1735  255 SER B O   
1913 C CB  . SER B 40  ? 1.0054 0.9086 0.8432 -0.0037 -0.0962 0.1517  255 SER B CB  
1914 O OG  . SER B 40  ? 1.0893 0.9377 0.9043 -0.0061 -0.1045 0.1906  255 SER B OG  
1915 N N   . GLN B 41  ? 1.0341 1.0160 0.8875 0.0595  -0.1216 0.1522  256 GLN B N   
1916 C CA  . GLN B 41  ? 1.0476 1.0434 0.8987 0.0865  -0.1382 0.1726  256 GLN B CA  
1917 C C   . GLN B 41  ? 1.0937 1.1373 0.9100 0.0776  -0.1485 0.2087  256 GLN B C   
1918 O O   . GLN B 41  ? 1.1057 1.1919 0.9188 0.0990  -0.1646 0.2226  256 GLN B O   
1919 C CB  . GLN B 41  ? 0.9643 1.0119 0.8492 0.1055  -0.1398 0.1359  256 GLN B CB  
1920 C CG  . GLN B 41  ? 0.9528 0.9587 0.8669 0.1094  -0.1280 0.1059  256 GLN B CG  
1921 C CD  . GLN B 41  ? 0.9020 0.9429 0.8486 0.1322  -0.1321 0.0844  256 GLN B CD  
1922 O OE1 . GLN B 41  ? 0.9026 0.9120 0.8620 0.1557  -0.1350 0.0879  256 GLN B OE1 
1923 N NE2 . GLN B 41  ? 0.8617 0.9706 0.8250 0.1243  -0.1317 0.0578  256 GLN B NE2 
1924 N N   . HIS B 42  ? 1.1069 1.1554 0.8970 0.0449  -0.1396 0.2239  257 HIS B N   
1925 C CA  A HIS B 42  ? 1.1201 1.2168 0.8697 0.0306  -0.1476 0.2655  257 HIS B CA  
1926 C CA  B HIS B 42  ? 1.1307 1.2027 0.8780 0.0276  -0.1469 0.2728  257 HIS B CA  
1927 C C   . HIS B 42  ? 1.1802 1.2418 0.9123 0.0557  -0.1703 0.3161  257 HIS B C   
1928 O O   . HIS B 42  ? 1.1944 1.2705 0.8861 0.0430  -0.1801 0.3674  257 HIS B O   
1929 C CB  A HIS B 42  ? 1.1262 1.2074 0.8493 -0.0102 -0.1352 0.2886  257 HIS B CB  
1930 C CB  B HIS B 42  ? 1.1568 1.1605 0.8848 -0.0048 -0.1381 0.3014  257 HIS B CB  
1931 C CG  A HIS B 42  ? 1.0881 1.2156 0.8301 -0.0299 -0.1157 0.2417  257 HIS B CG  
1932 C CG  B HIS B 42  ? 1.1946 1.0883 0.9411 0.0074  -0.1390 0.2996  257 HIS B CG  
1933 N ND1 A HIS B 42  ? 1.0840 1.1592 0.8548 -0.0307 -0.1058 0.2123  257 HIS B ND1 
1934 N ND1 B HIS B 42  ? 1.2014 1.0446 0.9529 -0.0190 -0.1259 0.2880  257 HIS B ND1 
1935 C CD2 A HIS B 42  ? 1.0410 1.2662 0.7791 -0.0454 -0.1058 0.2171  257 HIS B CD2 
1936 C CD2 B HIS B 42  ? 1.2001 1.0357 0.9639 0.0447  -0.1514 0.3012  257 HIS B CD2 
1937 C CE1 A HIS B 42  ? 1.0499 1.1839 0.8350 -0.0437 -0.0928 0.1765  257 HIS B CE1 
1938 C CE1 B HIS B 42  ? 1.2098 0.9646 0.9763 -0.0008 -0.1299 0.2826  257 HIS B CE1 
1939 N NE2 A HIS B 42  ? 1.0367 1.2605 0.8048 -0.0514 -0.0917 0.1755  257 HIS B NE2 
1940 N NE2 B HIS B 42  ? 1.2218 0.9705 0.9975 0.0395  -0.1444 0.2891  257 HIS B NE2 
1941 N N   . ALA B 48  ? 1.6483 1.5088 1.6851 0.4693  -0.3260 0.3699  263 ALA B N   
1942 C CA  . ALA B 48  ? 1.6159 1.4827 1.6664 0.4640  -0.2944 0.3096  263 ALA B CA  
1943 C C   . ALA B 48  ? 1.5590 1.5038 1.6660 0.5026  -0.2909 0.2599  263 ALA B C   
1944 O O   . ALA B 48  ? 1.5252 1.5503 1.6550 0.5254  -0.3105 0.2665  263 ALA B O   
1945 C CB  . ALA B 48  ? 1.5768 1.4940 1.5867 0.4214  -0.2829 0.2959  263 ALA B CB  
1946 N N   . PRO B 49  ? 1.6075 1.5322 1.7354 0.5074  -0.2663 0.2096  264 PRO B N   
1947 C CA  . PRO B 49  ? 1.5198 1.5297 1.6995 0.5364  -0.2585 0.1593  264 PRO B CA  
1948 C C   . PRO B 49  ? 1.4693 1.5594 1.6477 0.5074  -0.2401 0.1171  264 PRO B C   
1949 O O   . PRO B 49  ? 1.4676 1.5206 1.6088 0.4720  -0.2296 0.1180  264 PRO B O   
1950 C CB  . PRO B 49  ? 1.5174 1.4436 1.7202 0.5604  -0.2437 0.1338  264 PRO B CB  
1951 C CG  . PRO B 49  ? 1.5947 1.4137 1.7507 0.5225  -0.2311 0.1440  264 PRO B CG  
1952 C CD  . PRO B 49  ? 1.6641 1.4760 1.7735 0.4910  -0.2468 0.1995  264 PRO B CD  
1953 N N   . PRO B 50  ? 1.3845 1.5870 1.6053 0.5189  -0.2360 0.0808  265 PRO B N   
1954 C CA  . PRO B 50  ? 1.2726 1.5513 1.5003 0.4867  -0.2175 0.0417  265 PRO B CA  
1955 C C   . PRO B 50  ? 1.1859 1.4013 1.4074 0.4749  -0.1934 0.0128  265 PRO B C   
1956 O O   . PRO B 50  ? 1.2231 1.3693 1.4518 0.4971  -0.1862 0.0028  265 PRO B O   
1957 C CB  . PRO B 50  ? 1.2064 1.6066 1.4875 0.5023  -0.2157 0.0088  265 PRO B CB  
1958 C CG  . PRO B 50  ? 1.2381 1.6428 1.5301 0.5396  -0.2411 0.0401  265 PRO B CG  
1959 C CD  . PRO B 50  ? 1.3382 1.6068 1.6053 0.5586  -0.2483 0.0749  265 PRO B CD  
1960 N N   . LEU B 51  ? 1.0929 1.3247 1.2969 0.4222  -0.1749 -0.0008 266 LEU B N   
1961 C CA  . LEU B 51  ? 1.0456 1.2260 1.2396 0.3930  -0.1471 -0.0263 266 LEU B CA  
1962 C C   . LEU B 51  ? 0.9994 1.2407 1.2387 0.4149  -0.1316 -0.0699 266 LEU B C   
1963 O O   . LEU B 51  ? 0.9684 1.3112 1.2512 0.4395  -0.1381 -0.0851 266 LEU B O   
1964 C CB  . LEU B 51  ? 0.9911 1.1849 1.1628 0.3316  -0.1311 -0.0302 266 LEU B CB  
1965 C CG  . LEU B 51  ? 1.0379 1.1781 1.1654 0.3077  -0.1413 0.0048  266 LEU B CG  
1966 C CD1 . LEU B 51  ? 0.9764 1.1440 1.0936 0.2565  -0.1282 -0.0062 266 LEU B CD1 
1967 C CD2 . LEU B 51  ? 1.0666 1.0943 1.1617 0.3083  -0.1389 0.0216  266 LEU B CD2 
1968 N N   . GLU B 52  ? 0.9130 1.1018 1.1423 0.4049  -0.1107 -0.0921 267 GLU B N   
1969 C CA  . GLU B 52  ? 0.8581 1.1175 1.1257 0.4187  -0.0915 -0.1367 267 GLU B CA  
1970 C C   . GLU B 52  ? 0.7788 1.1263 1.0540 0.3660  -0.0715 -0.1507 267 GLU B C   
1971 O O   . GLU B 52  ? 0.8149 1.1400 1.0608 0.3192  -0.0698 -0.1309 267 GLU B O   
1972 C CB  . GLU B 52  ? 0.9182 1.1024 1.1695 0.4238  -0.0757 -0.1599 267 GLU B CB  
1973 C CG  . GLU B 52  ? 1.0008 1.0953 1.2545 0.4784  -0.0946 -0.1545 267 GLU B CG  
1974 C CD  . GLU B 52  ? 1.1532 1.1678 1.3886 0.4770  -0.0794 -0.1835 267 GLU B CD  
1975 O OE1 . GLU B 52  ? 1.1048 1.1744 1.3449 0.4575  -0.0533 -0.2227 267 GLU B OE1 
1976 O OE2 . GLU B 52  ? 1.2841 1.1847 1.4968 0.4847  -0.0916 -0.1639 267 GLU B OE2 
1977 N N   . SER B 53  ? 0.7360 1.1859 1.0535 0.3738  -0.0567 -0.1854 268 SER B N   
1978 C CA  . SER B 53  ? 0.6996 1.2323 1.0267 0.3194  -0.0370 -0.1962 268 SER B CA  
1979 C C   . SER B 53  ? 0.6986 1.2320 1.0117 0.2916  -0.0069 -0.2184 268 SER B C   
1980 O O   . SER B 53  ? 0.7113 1.2344 1.0294 0.3251  0.0015  -0.2439 268 SER B O   
1981 C CB  . SER B 53  ? 0.6558 1.3273 1.0409 0.3327  -0.0397 -0.2167 268 SER B CB  
1982 O OG  . SER B 53  ? 0.5895 1.3150 1.0148 0.3877  -0.0367 -0.2481 268 SER B OG  
1983 N N   . VAL B 54  ? 0.7323 1.2773 1.0269 0.2302  0.0082  -0.2088 269 VAL B N   
1984 C CA  . VAL B 54  ? 0.7347 1.3114 1.0180 0.1940  0.0371  -0.2237 269 VAL B CA  
1985 C C   . VAL B 54  ? 0.7337 1.4077 1.0432 0.1460  0.0494  -0.2246 269 VAL B C   
1986 O O   . VAL B 54  ? 0.7350 1.3994 1.0468 0.1197  0.0369  -0.2052 269 VAL B O   
1987 C CB  . VAL B 54  ? 0.7672 1.2415 0.9934 0.1612  0.0413  -0.2012 269 VAL B CB  
1988 C CG1 . VAL B 54  ? 0.7586 1.2754 0.9686 0.1161  0.0681  -0.2064 269 VAL B CG1 
1989 C CG2 . VAL B 54  ? 0.7984 1.1864 1.0022 0.2014  0.0322  -0.2065 269 VAL B CG2 
1990 N N   . ASP B 55  ? 0.6879 1.4589 1.0182 0.1323  0.0744  -0.2496 270 ASP B N   
1991 C CA  . ASP B 55  ? 0.6844 1.5555 1.0437 0.0814  0.0878  -0.2508 270 ASP B CA  
1992 C C   . ASP B 55  ? 0.7453 1.5529 1.0618 0.0134  0.0966  -0.2169 270 ASP B C   
1993 O O   . ASP B 55  ? 0.7806 1.5562 1.0579 -0.0053 0.1125  -0.2088 270 ASP B O   
1994 C CB  . ASP B 55  ? 0.6670 1.6724 1.0618 0.0855  0.1141  -0.2874 270 ASP B CB  
1995 C CG  . ASP B 55  ? 0.6648 1.7737 1.0834 0.0183  0.1334  -0.2847 270 ASP B CG  
1996 O OD1 . ASP B 55  ? 0.6751 1.7290 1.0617 -0.0443 0.1376  -0.2514 270 ASP B OD1 
1997 O OD2 . ASP B 55  ? 0.6657 1.8988 1.1314 0.0282  0.1413  -0.3139 270 ASP B OD2 
1998 N N   . VAL B 56  ? 0.7796 1.5697 1.1041 -0.0219 0.0848  -0.1986 271 VAL B N   
1999 C CA  . VAL B 56  ? 0.8462 1.5581 1.1345 -0.0783 0.0877  -0.1656 271 VAL B CA  
2000 C C   . VAL B 56  ? 0.8509 1.6068 1.1242 -0.1266 0.1162  -0.1572 271 VAL B C   
2001 O O   . VAL B 56  ? 0.9072 1.5897 1.1348 -0.1537 0.1206  -0.1279 271 VAL B O   
2002 C CB  . VAL B 56  ? 0.8309 1.5403 1.1429 -0.1115 0.0741  -0.1600 271 VAL B CB  
2003 C CG1 . VAL B 56  ? 0.8114 1.6538 1.1776 -0.1349 0.0841  -0.1840 271 VAL B CG1 
2004 C CG2 . VAL B 56  ? 0.8555 1.4754 1.1358 -0.1647 0.0757  -0.1280 271 VAL B CG2 
2005 N N   . ARG B 57  ? 0.7525 1.6380 1.0641 -0.1388 0.1355  -0.1812 272 ARG B N   
2006 C CA  . ARG B 57  ? 0.7602 1.7068 1.0569 -0.1908 0.1654  -0.1719 272 ARG B CA  
2007 C C   . ARG B 57  ? 0.8106 1.6982 1.0495 -0.1800 0.1733  -0.1592 272 ARG B C   
2008 O O   . ARG B 57  ? 0.8414 1.7192 1.0427 -0.2308 0.1880  -0.1287 272 ARG B O   
2009 C CB  . ARG B 57  ? 0.7010 1.8121 1.0471 -0.1851 0.1871  -0.2112 272 ARG B CB  
2010 C CG  . ARG B 57  ? 0.6686 1.8777 1.0784 -0.2033 0.1834  -0.2288 272 ARG B CG  
2011 C CD  . ARG B 57  ? 0.6667 1.9849 1.0996 -0.1664 0.1912  -0.2674 272 ARG B CD  
2012 N NE  . ARG B 57  ? 0.7017 2.0891 1.1814 -0.1514 0.1755  -0.2895 272 ARG B NE  
2013 C CZ  . ARG B 57  ? 0.7485 2.1542 1.2441 -0.2056 0.1716  -0.2789 272 ARG B CZ  
2014 N NH1 . ARG B 57  ? 0.7867 2.1228 1.2599 -0.2724 0.1763  -0.2442 272 ARG B NH1 
2015 N NH2 . ARG B 57  ? 0.7536 2.2428 1.2872 -0.1917 0.1614  -0.3040 272 ARG B NH2 
2016 N N   . GLN B 58  ? 0.8076 1.6557 1.0377 -0.1158 0.1622  -0.1813 273 GLN B N   
2017 C CA  . GLN B 58  ? 0.8200 1.6289 1.0011 -0.1025 0.1698  -0.1818 273 GLN B CA  
2018 C C   . GLN B 58  ? 0.9072 1.5906 1.0355 -0.1236 0.1553  -0.1387 273 GLN B C   
2019 O O   . GLN B 58  ? 0.9153 1.5720 0.9995 -0.1212 0.1604  -0.1355 273 GLN B O   
2020 C CB  . GLN B 58  ? 0.8522 1.6516 1.0468 -0.0294 0.1612  -0.2226 273 GLN B CB  
2021 C CG  . GLN B 58  ? 0.8268 1.7567 1.0600 -0.0013 0.1824  -0.2730 273 GLN B CG  
2022 C CD  . GLN B 58  ? 0.8473 1.8605 1.0526 -0.0416 0.2148  -0.2799 273 GLN B CD  
2023 O OE1 . GLN B 58  ? 0.8351 1.9524 1.0570 -0.0892 0.2357  -0.2741 273 GLN B OE1 
2024 N NE2 . GLN B 58  ? 0.8910 1.8650 1.0521 -0.0263 0.2195  -0.2928 273 GLN B NE2 
2025 N N   . ILE B 59  ? 1.0024 1.6156 1.1357 -0.1427 0.1369  -0.1097 274 ILE B N   
2026 C CA  . ILE B 59  ? 1.0431 1.5460 1.1339 -0.1598 0.1227  -0.0705 274 ILE B CA  
2027 C C   . ILE B 59  ? 1.0673 1.5517 1.1539 -0.2208 0.1250  -0.0314 274 ILE B C   
2028 O O   . ILE B 59  ? 1.1106 1.5031 1.1681 -0.2333 0.1113  0.0026  274 ILE B O   
2029 C CB  . ILE B 59  ? 1.0133 1.4272 1.1082 -0.1199 0.0958  -0.0724 274 ILE B CB  
2030 C CG1 . ILE B 59  ? 0.9811 1.4312 1.1255 -0.1018 0.0865  -0.0936 274 ILE B CG1 
2031 C CG2 . ILE B 59  ? 0.9541 1.3385 1.0285 -0.0732 0.0909  -0.0914 274 ILE B CG2 
2032 C CD1 . ILE B 59  ? 0.9336 1.3017 1.0774 -0.0809 0.0610  -0.0855 274 ILE B CD1 
2033 N N   . TYR B 60  ? 0.9966 1.5660 1.1135 -0.2597 0.1418  -0.0354 275 TYR B N   
2034 C CA  . TYR B 60  ? 1.0432 1.5861 1.1617 -0.3228 0.1432  0.0013  275 TYR B CA  
2035 C C   . TYR B 60  ? 1.0993 1.5726 1.1632 -0.3536 0.1428  0.0519  275 TYR B C   
2036 O O   . TYR B 60  ? 1.1431 1.5270 1.2014 -0.3807 0.1287  0.0867  275 TYR B O   
2037 C CB  . TYR B 60  ? 1.0076 1.6745 1.1613 -0.3661 0.1676  -0.0114 275 TYR B CB  
2038 C CG  . TYR B 60  ? 0.9752 1.6931 1.1904 -0.3568 0.1602  -0.0471 275 TYR B CG  
2039 C CD1 . TYR B 60  ? 0.9176 1.6097 1.1512 -0.2942 0.1389  -0.0763 275 TYR B CD1 
2040 C CD2 . TYR B 60  ? 0.9377 1.7266 1.1904 -0.4150 0.1724  -0.0478 275 TYR B CD2 
2041 C CE1 . TYR B 60  ? 0.8652 1.6106 1.1507 -0.2850 0.1290  -0.1057 275 TYR B CE1 
2042 C CE2 . TYR B 60  ? 0.9283 1.7740 1.2376 -0.4075 0.1632  -0.0829 275 TYR B CE2 
2043 C CZ  . TYR B 60  ? 0.8712 1.6962 1.1954 -0.3409 0.1405  -0.1110 275 TYR B CZ  
2044 O OH  . TYR B 60  ? 0.8282 1.7178 1.2048 -0.3330 0.1287  -0.1429 275 TYR B OH  
2045 N N   . ASP B 61  ? 1.1766 1.6926 1.2010 -0.3489 0.1571  0.0553  276 ASP B N   
2046 C CA  . ASP B 61  ? 1.2051 1.6795 1.1742 -0.3815 0.1573  0.1067  276 ASP B CA  
2047 C C   . ASP B 61  ? 1.2335 1.5967 1.1723 -0.3470 0.1306  0.1245  276 ASP B C   
2048 O O   . ASP B 61  ? 1.2494 1.5647 1.1470 -0.3702 0.1234  0.1730  276 ASP B O   
2049 C CB  . ASP B 61  ? 1.2508 1.8302 1.1860 -0.3904 0.1830  0.0981  276 ASP B CB  
2050 C CG  . ASP B 61  ? 1.2994 1.9302 1.2484 -0.3307 0.1877  0.0364  276 ASP B CG  
2051 O OD1 . ASP B 61  ? 1.2428 1.9463 1.2410 -0.3145 0.1979  -0.0056 276 ASP B OD1 
2052 O OD2 . ASP B 61  ? 1.3400 1.9331 1.2537 -0.2986 0.1785  0.0298  276 ASP B OD2 
2053 N N   . LYS B 62  ? 1.1790 1.5062 1.1368 -0.2935 0.1154  0.0894  277 LYS B N   
2054 C CA  . LYS B 62  ? 1.1489 1.3857 1.0829 -0.2619 0.0919  0.1011  277 LYS B CA  
2055 C C   . LYS B 62  ? 1.1326 1.2739 1.0851 -0.2650 0.0697  0.1231  277 LYS B C   
2056 O O   . LYS B 62  ? 1.0996 1.1719 1.0360 -0.2411 0.0502  0.1350  277 LYS B O   
2057 C CB  . LYS B 62  ? 1.0988 1.3408 1.0416 -0.2079 0.0871  0.0558  277 LYS B CB  
2058 C CG  . LYS B 62  ? 1.0951 1.4301 1.0398 -0.1943 0.1084  0.0167  277 LYS B CG  
2059 C CD  . LYS B 62  ? 1.0393 1.3517 0.9645 -0.1515 0.1014  -0.0107 277 LYS B CD  
2060 C CE  . LYS B 62  ? 1.0357 1.3324 0.9064 -0.1670 0.0990  0.0135  277 LYS B CE  
2061 N NZ  . LYS B 62  ? 0.9913 1.3796 0.8347 -0.1862 0.1228  0.0014  277 LYS B NZ  
2062 N N   . PHE B 63  ? 1.1451 1.2862 1.1331 -0.2952 0.0725  0.1249  278 PHE B N   
2063 C CA  . PHE B 63  ? 1.1761 1.2284 1.1871 -0.2958 0.0520  0.1334  278 PHE B CA  
2064 C C   . PHE B 63  ? 1.2372 1.2583 1.2565 -0.3523 0.0547  0.1683  278 PHE B C   
2065 O O   . PHE B 63  ? 1.2303 1.3120 1.2400 -0.3951 0.0747  0.1859  278 PHE B O   
2066 C CB  . PHE B 63  ? 1.1216 1.1904 1.1749 -0.2670 0.0462  0.0866  278 PHE B CB  
2067 C CG  . PHE B 63  ? 1.0397 1.1220 1.0841 -0.2146 0.0411  0.0599  278 PHE B CG  
2068 C CD1 . PHE B 63  ? 0.9999 1.1613 1.0442 -0.1983 0.0561  0.0351  278 PHE B CD1 
2069 C CD2 . PHE B 63  ? 0.9630 0.9790 1.0003 -0.1825 0.0218  0.0592  278 PHE B CD2 
2070 C CE1 . PHE B 63  ? 0.9752 1.1336 1.0117 -0.1523 0.0500  0.0128  278 PHE B CE1 
2071 C CE2 . PHE B 63  ? 0.9127 0.9364 0.9401 -0.1420 0.0176  0.0392  278 PHE B CE2 
2072 C CZ  . PHE B 63  ? 0.9032 0.9905 0.9295 -0.1276 0.0309  0.0174  278 PHE B CZ  
2073 N N   . PRO B 64  ? 1.3529 1.2807 1.3919 -0.3563 0.0357  0.1772  279 PRO B N   
2074 C CA  . PRO B 64  ? 1.4204 1.2950 1.4643 -0.4114 0.0355  0.2162  279 PRO B CA  
2075 C C   . PRO B 64  ? 1.4260 1.3681 1.5029 -0.4625 0.0548  0.1999  279 PRO B C   
2076 O O   . PRO B 64  ? 1.3779 1.4306 1.4640 -0.4596 0.0734  0.1698  279 PRO B O   
2077 C CB  . PRO B 64  ? 1.4349 1.1970 1.5018 -0.3913 0.0097  0.2112  279 PRO B CB  
2078 C CG  . PRO B 64  ? 1.4107 1.2017 1.5002 -0.3423 0.0037  0.1557  279 PRO B CG  
2079 C CD  . PRO B 64  ? 1.3358 1.2163 1.4014 -0.3151 0.0168  0.1429  279 PRO B CD  
2080 N N   . GLU B 65  ? 1.5179 1.3927 1.6164 -0.5092 0.0495  0.2178  280 GLU B N   
2081 C CA  . GLU B 65  ? 1.5435 1.4778 1.6724 -0.5677 0.0678  0.2092  280 GLU B CA  
2082 C C   . GLU B 65  ? 1.6213 1.4525 1.7764 -0.5898 0.0573  0.2179  280 GLU B C   
2083 O O   . GLU B 65  ? 1.6577 1.3771 1.8149 -0.5619 0.0357  0.2207  280 GLU B O   
2084 C CB  . GLU B 65  ? 1.4857 1.5075 1.5824 -0.5931 0.0927  0.2390  280 GLU B CB  
2085 C CG  . GLU B 65  ? 1.4516 1.5945 1.5806 -0.6282 0.1163  0.2105  280 GLU B CG  
2086 C CD  . GLU B 65  ? 1.4108 1.6876 1.5183 -0.6198 0.1399  0.2011  280 GLU B CD  
2087 O OE1 . GLU B 65  ? 1.4054 1.6807 1.4753 -0.5875 0.1381  0.2110  280 GLU B OE1 
2088 O OE2 . GLU B 65  ? 1.3231 1.7061 1.4510 -0.6449 0.1600  0.1827  280 GLU B OE2 
2089 N N   . LYS B 66  ? 1.6486 1.5199 1.8280 -0.6377 0.0731  0.2169  281 LYS B N   
2090 C CA  . LYS B 66  ? 1.7208 1.4951 1.9279 -0.6655 0.0670  0.2254  281 LYS B CA  
2091 C C   . LYS B 66  ? 1.7188 1.4473 1.9764 -0.6519 0.0498  0.1702  281 LYS B C   
2092 O O   . LYS B 66  ? 1.7861 1.4571 2.0812 -0.6797 0.0475  0.1594  281 LYS B O   
2093 C CB  . LYS B 66  ? 1.8030 1.4571 1.9715 -0.6516 0.0570  0.2807  281 LYS B CB  
2094 N N   . LYS B 67  ? 1.6047 1.3606 1.8629 -0.6107 0.0378  0.1337  282 LYS B N   
2095 C CA  . LYS B 67  ? 1.5562 1.2749 1.8511 -0.5893 0.0187  0.0793  282 LYS B CA  
2096 C C   . LYS B 67  ? 1.5887 1.3057 1.8561 -0.5367 0.0047  0.0682  282 LYS B C   
2097 O O   . LYS B 67  ? 1.6366 1.3435 1.8621 -0.5115 0.0058  0.1086  282 LYS B O   
2098 C CB  . LYS B 67  ? 1.6195 1.2047 1.9351 -0.5922 0.0089  0.0797  282 LYS B CB  
2099 C CG  . LYS B 67  ? 1.6054 1.1170 1.9251 -0.5458 -0.0106 0.0377  282 LYS B CG  
2100 N N   . GLY B 68  ? 1.4668 1.2114 1.7589 -0.5026 -0.0059 0.0109  283 GLY B N   
2101 C CA  . GLY B 68  ? 1.3966 1.1531 1.6681 -0.4307 -0.0153 -0.0030 283 GLY B CA  
2102 C C   . GLY B 68  ? 1.3788 1.1999 1.6124 -0.4070 -0.0024 0.0269  283 GLY B C   
2103 O O   . GLY B 68  ? 1.3469 1.1412 1.5512 -0.3600 -0.0099 0.0403  283 GLY B O   
2104 N N   . GLY B 69  ? 1.3144 1.2264 1.5509 -0.4414 0.0176  0.0334  284 GLY B N   
2105 C CA  . GLY B 69  ? 1.2637 1.2518 1.4701 -0.4206 0.0324  0.0494  284 GLY B CA  
2106 C C   . GLY B 69  ? 1.1524 1.2590 1.3828 -0.3980 0.0396  0.0056  284 GLY B C   
2107 O O   . GLY B 69  ? 1.1286 1.2874 1.3990 -0.4227 0.0404  -0.0257 284 GLY B O   
2108 N N   . LEU B 70  ? 1.1984 1.3461 1.4053 -0.3502 0.0429  0.0031  285 LEU B N   
2109 C CA  . LEU B 70  ? 1.1144 1.3640 1.3420 -0.3177 0.0467  -0.0333 285 LEU B CA  
2110 C C   . LEU B 70  ? 1.1052 1.4570 1.3754 -0.3573 0.0593  -0.0546 285 LEU B C   
2111 O O   . LEU B 70  ? 1.0731 1.4794 1.3783 -0.3452 0.0502  -0.0901 285 LEU B O   
2112 C CB  . LEU B 70  ? 1.0220 1.3066 1.2193 -0.2831 0.0573  -0.0254 285 LEU B CB  
2113 C CG  . LEU B 70  ? 0.9810 1.2369 1.1620 -0.2217 0.0430  -0.0374 285 LEU B CG  
2114 C CD1 . LEU B 70  ? 0.9585 1.2613 1.1198 -0.1935 0.0555  -0.0404 285 LEU B CD1 
2115 C CD2 . LEU B 70  ? 0.9439 1.2336 1.1579 -0.1974 0.0290  -0.0703 285 LEU B CD2 
2116 N N   . ARG B 71  ? 1.0420 1.4320 1.3090 -0.4062 0.0804  -0.0324 286 ARG B N   
2117 C CA  . ARG B 71  ? 1.0229 1.5148 1.3319 -0.4566 0.0953  -0.0488 286 ARG B CA  
2118 C C   . ARG B 71  ? 1.0122 1.4840 1.3606 -0.4834 0.0800  -0.0744 286 ARG B C   
2119 O O   . ARG B 71  ? 0.9643 1.5280 1.3523 -0.4715 0.0750  -0.1146 286 ARG B O   
2120 C CB  . ARG B 71  ? 1.1145 1.6108 1.4060 -0.5228 0.1176  -0.0081 286 ARG B CB  
2121 C CG  . ARG B 71  ? 1.0984 1.7343 1.3932 -0.5321 0.1457  -0.0133 286 ARG B CG  
2122 C CD  . ARG B 71  ? 1.1461 1.7696 1.4074 -0.5893 0.1641  0.0339  286 ARG B CD  
2123 N NE  . ARG B 71  ? 1.2634 1.8316 1.4676 -0.5789 0.1673  0.0733  286 ARG B NE  
2124 C CZ  . ARG B 71  ? 1.2506 1.8903 1.4217 -0.5731 0.1872  0.0822  286 ARG B CZ  
2125 N NH1 . ARG B 71  ? 1.1548 1.9206 1.3434 -0.5780 0.2070  0.0562  286 ARG B NH1 
2126 N NH2 . ARG B 71  ? 1.2541 1.8389 1.3715 -0.5605 0.1854  0.1153  286 ARG B NH2 
2127 N N   . GLU B 72  ? 1.0586 1.4126 1.3975 -0.5196 0.0714  -0.0525 287 GLU B N   
2128 C CA  . GLU B 72  ? 1.0707 1.3949 1.4470 -0.5518 0.0578  -0.0818 287 GLU B CA  
2129 C C   . GLU B 72  ? 1.0661 1.4096 1.4558 -0.4950 0.0371  -0.1264 287 GLU B C   
2130 O O   . GLU B 72  ? 1.0360 1.4679 1.4653 -0.5039 0.0322  -0.1675 287 GLU B O   
2131 C CB  . GLU B 72  ? 1.1768 1.3483 1.5371 -0.5844 0.0490  -0.0508 287 GLU B CB  
2132 C CG  . GLU B 72  ? 1.2521 1.3971 1.6402 -0.6321 0.0487  -0.0484 287 GLU B CG  
2133 C CD  . GLU B 72  ? 1.3587 1.3907 1.7643 -0.6288 0.0247  -0.0700 287 GLU B CD  
2134 O OE1 . GLU B 72  ? 1.3464 1.3655 1.7488 -0.5868 0.0104  -0.1032 287 GLU B OE1 
2135 O OE2 . GLU B 72  ? 1.4065 1.3678 1.8315 -0.6663 0.0207  -0.0568 287 GLU B OE2 
2136 N N   . LEU B 73  ? 1.1782 1.4464 1.5339 -0.4385 0.0242  -0.1172 288 LEU B N   
2137 C CA  . LEU B 73  ? 1.1427 1.4318 1.5032 -0.3860 0.0059  -0.1521 288 LEU B CA  
2138 C C   . LEU B 73  ? 1.0788 1.5048 1.4605 -0.3607 0.0084  -0.1754 288 LEU B C   
2139 O O   . LEU B 73  ? 1.0652 1.5553 1.4750 -0.3554 -0.0044 -0.2121 288 LEU B O   
2140 C CB  . LEU B 73  ? 1.1149 1.3266 1.4336 -0.3303 -0.0031 -0.1329 288 LEU B CB  
2141 C CG  . LEU B 73  ? 1.1539 1.2371 1.4547 -0.3292 -0.0139 -0.1192 288 LEU B CG  
2142 C CD1 . LEU B 73  ? 1.2024 1.2535 1.5355 -0.3579 -0.0253 -0.1551 288 LEU B CD1 
2143 C CD2 . LEU B 73  ? 1.2856 1.3005 1.5635 -0.3553 -0.0040 -0.0715 288 LEU B CD2 
2144 N N   . TYR B 74  ? 1.0092 1.4852 1.3784 -0.3425 0.0234  -0.1563 289 TYR B N   
2145 C CA  . TYR B 74  ? 0.9227 1.5231 1.3155 -0.3084 0.0241  -0.1785 289 TYR B CA  
2146 C C   . TYR B 74  ? 0.9378 1.6524 1.3827 -0.3534 0.0296  -0.2062 289 TYR B C   
2147 O O   . TYR B 74  ? 0.9110 1.7351 1.3863 -0.3241 0.0217  -0.2328 289 TYR B O   
2148 C CB  . TYR B 74  ? 0.8836 1.5110 1.2558 -0.2793 0.0405  -0.1598 289 TYR B CB  
2149 C CG  . TYR B 74  ? 0.8198 1.5410 1.2111 -0.2215 0.0344  -0.1817 289 TYR B CG  
2150 C CD1 . TYR B 74  ? 0.8186 1.6757 1.2580 -0.2294 0.0411  -0.2071 289 TYR B CD1 
2151 C CD2 . TYR B 74  ? 0.7961 1.4703 1.1601 -0.1594 0.0208  -0.1760 289 TYR B CD2 
2152 C CE1 . TYR B 74  ? 0.7739 1.7143 1.2351 -0.1699 0.0321  -0.2258 289 TYR B CE1 
2153 C CE2 . TYR B 74  ? 0.7692 1.5154 1.1513 -0.1047 0.0123  -0.1914 289 TYR B CE2 
2154 C CZ  . TYR B 74  ? 0.7502 1.6278 1.1816 -0.1067 0.0169  -0.2161 289 TYR B CZ  
2155 O OH  . TYR B 74  ? 0.7144 1.6631 1.1684 -0.0458 0.0055  -0.2302 289 TYR B OH  
2156 N N   . ASP B 75  ? 0.9715 1.6636 1.4290 -0.4251 0.0413  -0.1991 290 ASP B N   
2157 C CA  . ASP B 75  ? 0.9362 1.7120 1.4331 -0.4660 0.0438  -0.2233 290 ASP B CA  
2158 C C   . ASP B 75  ? 0.9314 1.6907 1.4419 -0.4618 0.0200  -0.2566 290 ASP B C   
2159 O O   . ASP B 75  ? 0.9212 1.7781 1.4535 -0.4428 0.0113  -0.2845 290 ASP B O   
2160 C CB  . ASP B 75  ? 0.9623 1.6893 1.4525 -0.5332 0.0616  -0.1952 290 ASP B CB  
2161 C CG  . ASP B 75  ? 0.9533 1.7642 1.4394 -0.5421 0.0872  -0.1768 290 ASP B CG  
2162 O OD1 . ASP B 75  ? 0.9317 1.8435 1.4280 -0.4930 0.0899  -0.1944 290 ASP B OD1 
2163 O OD2 . ASP B 75  ? 1.0202 1.8015 1.4950 -0.5950 0.1032  -0.1476 290 ASP B OD2 
2164 N N   . ARG B 76  ? 1.0047 1.6420 1.4999 -0.4766 0.0092  -0.2551 291 ARG B N   
2165 C CA  . ARG B 76  ? 1.0278 1.6483 1.5307 -0.4696 -0.0122 -0.2911 291 ARG B CA  
2166 C C   . ARG B 76  ? 0.9596 1.6624 1.4617 -0.4079 -0.0291 -0.3137 291 ARG B C   
2167 O O   . ARG B 76  ? 0.9192 1.6617 1.4281 -0.3997 -0.0440 -0.3444 291 ARG B O   
2168 C CB  . ARG B 76  ? 1.1154 1.5880 1.5992 -0.4801 -0.0207 -0.2871 291 ARG B CB  
2169 C CG  . ARG B 76  ? 1.1784 1.5619 1.6697 -0.5390 -0.0160 -0.2744 291 ARG B CG  
2170 C CD  . ARG B 76  ? 1.3249 1.5659 1.7905 -0.5451 -0.0138 -0.2370 291 ARG B CD  
2171 N NE  . ARG B 76  ? 1.4746 1.6088 1.9485 -0.5877 -0.0200 -0.2283 291 ARG B NE  
2172 C CZ  . ARG B 76  ? 1.5452 1.5396 2.0019 -0.5847 -0.0287 -0.2058 291 ARG B CZ  
2173 N NH1 . ARG B 76  ? 1.5302 1.4754 1.9588 -0.5438 -0.0294 -0.1907 291 ARG B NH1 
2174 N NH2 . ARG B 76  ? 1.5218 1.4234 1.9917 -0.6216 -0.0387 -0.1980 291 ARG B NH2 
2175 N N   . GLY B 77  ? 0.8336 1.5614 1.3250 -0.3639 -0.0278 -0.2964 292 GLY B N   
2176 C CA  . GLY B 77  ? 0.7365 1.5335 1.2225 -0.2995 -0.0447 -0.3047 292 GLY B CA  
2177 C C   . GLY B 77  ? 0.7210 1.4467 1.1745 -0.2678 -0.0635 -0.3101 292 GLY B C   
2178 O O   . GLY B 77  ? 0.7651 1.3844 1.2021 -0.2889 -0.0627 -0.3102 292 GLY B O   
2179 N N   . PRO B 78  ? 0.6478 1.4347 1.0920 -0.2151 -0.0812 -0.3134 293 PRO B N   
2180 C CA  . PRO B 78  ? 0.5740 1.4774 1.0376 -0.1764 -0.0874 -0.3104 293 PRO B CA  
2181 C C   . PRO B 78  ? 0.5776 1.4358 1.0131 -0.1258 -0.0794 -0.2726 293 PRO B C   
2182 O O   . PRO B 78  ? 0.6143 1.3672 1.0075 -0.1071 -0.0787 -0.2500 293 PRO B O   
2183 C CB  . PRO B 78  ? 0.5449 1.4884 0.9916 -0.1447 -0.1111 -0.3224 293 PRO B CB  
2184 C CG  . PRO B 78  ? 0.5797 1.4295 0.9923 -0.1415 -0.1182 -0.3204 293 PRO B CG  
2185 C CD  . PRO B 78  ? 0.6423 1.3886 1.0561 -0.1901 -0.0987 -0.3215 293 PRO B CD  
2186 N N   . PRO B 79  ? 0.5426 1.4831 1.0035 -0.1020 -0.0736 -0.2697 294 PRO B N   
2187 C CA  . PRO B 79  ? 0.5812 1.4709 1.0185 -0.0618 -0.0620 -0.2419 294 PRO B CA  
2188 C C   . PRO B 79  ? 0.5717 1.3978 0.9692 -0.0049 -0.0791 -0.2192 294 PRO B C   
2189 O O   . PRO B 79  ? 0.6014 1.3387 0.9655 0.0126  -0.0699 -0.1963 294 PRO B O   
2190 C CB  . PRO B 79  ? 0.5262 1.5396 1.0090 -0.0435 -0.0554 -0.2554 294 PRO B CB  
2191 C CG  . PRO B 79  ? 0.4336 1.5482 0.9503 -0.0657 -0.0659 -0.2817 294 PRO B CG  
2192 C CD  . PRO B 79  ? 0.4683 1.5379 0.9690 -0.0993 -0.0791 -0.2912 294 PRO B CD  
2193 N N   . HIS B 80  ? 0.5466 1.4182 0.9446 0.0199  -0.1041 -0.2236 295 HIS B N   
2194 C CA  . HIS B 80  ? 0.5461 1.3613 0.9040 0.0683  -0.1205 -0.1962 295 HIS B CA  
2195 C C   . HIS B 80  ? 0.5839 1.2855 0.8964 0.0502  -0.1160 -0.1832 295 HIS B C   
2196 O O   . HIS B 80  ? 0.5935 1.2462 0.8703 0.0817  -0.1267 -0.1589 295 HIS B O   
2197 C CB  . HIS B 80  ? 0.5321 1.4333 0.8966 0.0946  -0.1493 -0.1992 295 HIS B CB  
2198 C CG  . HIS B 80  ? 0.5590 1.4793 0.9162 0.0560  -0.1580 -0.2216 295 HIS B CG  
2199 N ND1 . HIS B 80  ? 0.5484 1.5394 0.9360 0.0152  -0.1552 -0.2563 295 HIS B ND1 
2200 C CD2 . HIS B 80  ? 0.5697 1.4338 0.8861 0.0504  -0.1647 -0.2161 295 HIS B CD2 
2201 C CE1 . HIS B 80  ? 0.5551 1.5288 0.9222 -0.0111 -0.1609 -0.2739 295 HIS B CE1 
2202 N NE2 . HIS B 80  ? 0.5671 1.4828 0.8979 0.0104  -0.1695 -0.2543 295 HIS B NE2 
2203 N N   . ALA B 81  ? 0.6178 1.2766 0.9325 0.0010  -0.1011 -0.1969 296 ALA B N   
2204 C CA  . ALA B 81  ? 0.6403 1.1986 0.9199 -0.0130 -0.0979 -0.1888 296 ALA B CA  
2205 C C   . ALA B 81  ? 0.6732 1.1405 0.9299 -0.0120 -0.0808 -0.1645 296 ALA B C   
2206 O O   . ALA B 81  ? 0.6862 1.0746 0.9135 -0.0139 -0.0801 -0.1535 296 ALA B O   
2207 C CB  . ALA B 81  ? 0.6224 1.1764 0.9194 -0.0628 -0.0955 -0.2189 296 ALA B CB  
2208 N N   . PHE B 82  ? 0.6482 1.1353 0.9186 -0.0094 -0.0672 -0.1590 297 PHE B N   
2209 C CA  . PHE B 82  ? 0.7054 1.1236 0.9556 -0.0184 -0.0495 -0.1413 297 PHE B CA  
2210 C C   . PHE B 82  ? 0.7350 1.1254 0.9623 0.0265  -0.0503 -0.1241 297 PHE B C   
2211 O O   . PHE B 82  ? 0.6982 1.1441 0.9426 0.0600  -0.0553 -0.1290 297 PHE B O   
2212 C CB  . PHE B 82  ? 0.7381 1.2031 1.0152 -0.0525 -0.0308 -0.1493 297 PHE B CB  
2213 C CG  . PHE B 82  ? 0.7480 1.2115 1.0437 -0.1067 -0.0275 -0.1607 297 PHE B CG  
2214 C CD1 . PHE B 82  ? 0.7348 1.2643 1.0623 -0.1213 -0.0388 -0.1877 297 PHE B CD1 
2215 C CD2 . PHE B 82  ? 0.7895 1.1814 1.0701 -0.1436 -0.0151 -0.1439 297 PHE B CD2 
2216 C CE1 . PHE B 82  ? 0.7788 1.2969 1.1254 -0.1743 -0.0364 -0.2027 297 PHE B CE1 
2217 C CE2 . PHE B 82  ? 0.8537 1.2273 1.1526 -0.1935 -0.0139 -0.1522 297 PHE B CE2 
2218 C CZ  . PHE B 82  ? 0.8454 1.2787 1.1786 -0.2104 -0.0238 -0.1842 297 PHE B CZ  
2219 N N   . PHE B 83  ? 0.7288 1.0336 0.9206 0.0270  -0.0462 -0.1060 298 PHE B N   
2220 C CA  . PHE B 83  ? 0.7601 1.0242 0.9277 0.0619  -0.0472 -0.0922 298 PHE B CA  
2221 C C   . PHE B 83  ? 0.7394 0.9493 0.8836 0.0458  -0.0318 -0.0831 298 PHE B C   
2222 O O   . PHE B 83  ? 0.6898 0.8679 0.8253 0.0137  -0.0269 -0.0765 298 PHE B O   
2223 C CB  . PHE B 83  ? 0.7623 0.9830 0.9043 0.0811  -0.0636 -0.0773 298 PHE B CB  
2224 C CG  . PHE B 83  ? 0.7567 1.0337 0.9123 0.1021  -0.0811 -0.0799 298 PHE B CG  
2225 C CD1 . PHE B 83  ? 0.7299 1.0479 0.8968 0.0817  -0.0888 -0.0932 298 PHE B CD1 
2226 C CD2 . PHE B 83  ? 0.7337 1.0224 0.8907 0.1433  -0.0917 -0.0696 298 PHE B CD2 
2227 C CE1 . PHE B 83  ? 0.7083 1.0900 0.8839 0.0998  -0.1066 -0.0957 298 PHE B CE1 
2228 C CE2 . PHE B 83  ? 0.7680 1.1134 0.9349 0.1650  -0.1112 -0.0658 298 PHE B CE2 
2229 C CZ  . PHE B 83  ? 0.7221 1.1202 0.8963 0.1420  -0.1187 -0.0785 298 PHE B CZ  
2230 N N   . LEU B 84  ? 0.7841 0.9823 0.9179 0.0702  -0.0262 -0.0834 299 LEU B N   
2231 C CA  . LEU B 84  ? 0.7713 0.9230 0.8767 0.0590  -0.0143 -0.0769 299 LEU B CA  
2232 C C   . LEU B 84  ? 0.7349 0.8209 0.8127 0.0824  -0.0239 -0.0673 299 LEU B C   
2233 O O   . LEU B 84  ? 0.7521 0.8362 0.8356 0.1161  -0.0308 -0.0722 299 LEU B O   
2234 C CB  . LEU B 84  ? 0.7442 0.9464 0.8602 0.0613  0.0034  -0.0941 299 LEU B CB  
2235 C CG  . LEU B 84  ? 0.7453 0.9189 0.8318 0.0609  0.0152  -0.0972 299 LEU B CG  
2236 C CD1 . LEU B 84  ? 0.7633 0.9193 0.8252 0.0189  0.0235  -0.0786 299 LEU B CD1 
2237 C CD2 . LEU B 84  ? 0.7543 0.9941 0.8593 0.0781  0.0305  -0.1255 299 LEU B CD2 
2238 N N   . VAL B 85  ? 0.7499 0.7824 0.8007 0.0645  -0.0257 -0.0526 300 VAL B N   
2239 C CA  . VAL B 85  ? 0.7833 0.7583 0.8073 0.0760  -0.0317 -0.0446 300 VAL B CA  
2240 C C   . VAL B 85  ? 0.7920 0.7509 0.7951 0.0635  -0.0202 -0.0495 300 VAL B C   
2241 O O   . VAL B 85  ? 0.7687 0.7355 0.7643 0.0379  -0.0140 -0.0423 300 VAL B O   
2242 C CB  . VAL B 85  ? 0.7750 0.7184 0.7860 0.0658  -0.0426 -0.0282 300 VAL B CB  
2243 C CG1 . VAL B 85  ? 0.8032 0.6967 0.7900 0.0732  -0.0480 -0.0195 300 VAL B CG1 
2244 C CG2 . VAL B 85  ? 0.7590 0.7329 0.7872 0.0733  -0.0528 -0.0272 300 VAL B CG2 
2245 N N   . LYS B 86  ? 0.7780 0.7151 0.7716 0.0817  -0.0184 -0.0622 301 LYS B N   
2246 C CA  . LYS B 86  ? 0.8032 0.7215 0.7709 0.0693  -0.0107 -0.0705 301 LYS B CA  
2247 C C   . LYS B 86  ? 0.8159 0.6741 0.7621 0.0657  -0.0218 -0.0600 301 LYS B C   
2248 O O   . LYS B 86  ? 0.8386 0.6604 0.7875 0.0841  -0.0301 -0.0597 301 LYS B O   
2249 C CB  . LYS B 86  ? 0.7926 0.7313 0.7656 0.0884  0.0006  -0.1017 301 LYS B CB  
2250 C CG  . LYS B 86  ? 0.8441 0.7547 0.7880 0.0801  0.0051  -0.1180 301 LYS B CG  
2251 C CD  . LYS B 86  ? 0.8750 0.8461 0.8085 0.0654  0.0231  -0.1363 301 LYS B CD  
2252 C CE  . LYS B 86  ? 0.9221 0.8778 0.8311 0.0657  0.0283  -0.1675 301 LYS B CE  
2253 N NZ  . LYS B 86  ? 0.9485 0.9763 0.8532 0.0634  0.0483  -0.1979 301 LYS B NZ  
2254 N N   . PHE B 87  ? 0.7893 0.6407 0.7159 0.0413  -0.0232 -0.0485 302 PHE B N   
2255 C CA  . PHE B 87  ? 0.8493 0.6622 0.7576 0.0306  -0.0320 -0.0406 302 PHE B CA  
2256 C C   . PHE B 87  ? 0.9108 0.7149 0.7962 0.0204  -0.0273 -0.0592 302 PHE B C   
2257 O O   . PHE B 87  ? 0.8543 0.6935 0.7290 0.0107  -0.0190 -0.0663 302 PHE B O   
2258 C CB  . PHE B 87  ? 0.8308 0.6547 0.7377 0.0142  -0.0384 -0.0199 302 PHE B CB  
2259 C CG  . PHE B 87  ? 0.8458 0.6715 0.7702 0.0207  -0.0453 -0.0077 302 PHE B CG  
2260 C CD1 . PHE B 87  ? 0.8284 0.6337 0.7527 0.0290  -0.0514 -0.0033 302 PHE B CD1 
2261 C CD2 . PHE B 87  ? 0.8095 0.6568 0.7485 0.0164  -0.0463 -0.0006 302 PHE B CD2 
2262 C CE1 . PHE B 87  ? 0.8180 0.6379 0.7535 0.0332  -0.0574 0.0065  302 PHE B CE1 
2263 C CE2 . PHE B 87  ? 0.8258 0.6811 0.7805 0.0217  -0.0525 0.0027  302 PHE B CE2 
2264 C CZ  . PHE B 87  ? 0.8170 0.6654 0.7683 0.0304  -0.0576 0.0054  302 PHE B CZ  
2265 N N   . TRP B 88  ? 0.8919 0.6515 0.7680 0.0187  -0.0328 -0.0668 303 TRP B N   
2266 C CA  . TRP B 88  ? 0.9386 0.6891 0.7919 -0.0005 -0.0328 -0.0836 303 TRP B CA  
2267 C C   . TRP B 88  ? 0.9379 0.6874 0.7846 -0.0221 -0.0434 -0.0623 303 TRP B C   
2268 O O   . TRP B 88  ? 0.9292 0.6434 0.7765 -0.0297 -0.0497 -0.0564 303 TRP B O   
2269 C CB  . TRP B 88  ? 0.9754 0.6747 0.8266 0.0084  -0.0316 -0.1117 303 TRP B CB  
2270 C CG  . TRP B 88  ? 0.9910 0.7078 0.8505 0.0321  -0.0200 -0.1419 303 TRP B CG  
2271 C CD1 . TRP B 88  ? 0.9837 0.7315 0.8286 0.0272  -0.0093 -0.1767 303 TRP B CD1 
2272 C CD2 . TRP B 88  ? 0.9891 0.7073 0.8755 0.0654  -0.0176 -0.1430 303 TRP B CD2 
2273 N NE1 . TRP B 88  ? 0.9818 0.7512 0.8449 0.0559  0.0017  -0.2017 303 TRP B NE1 
2274 C CE2 . TRP B 88  ? 1.0033 0.7562 0.8943 0.0807  -0.0041 -0.1808 303 TRP B CE2 
2275 C CE3 . TRP B 88  ? 0.9821 0.6862 0.8890 0.0839  -0.0263 -0.1168 303 TRP B CE3 
2276 C CZ2 . TRP B 88  ? 1.0381 0.8128 0.9592 0.1163  0.0009  -0.1942 303 TRP B CZ2 
2277 C CZ3 . TRP B 88  ? 0.9911 0.7146 0.9247 0.1185  -0.0237 -0.1274 303 TRP B CZ3 
2278 C CH2 . TRP B 88  ? 1.0322 0.7916 0.9755 0.1352  -0.0102 -0.1659 303 TRP B CH2 
2279 N N   . ALA B 89  ? 0.8753 0.6669 0.7167 -0.0323 -0.0455 -0.0497 304 ALA B N   
2280 C CA  . ALA B 89  ? 0.9244 0.7306 0.7662 -0.0464 -0.0562 -0.0323 304 ALA B CA  
2281 C C   . ALA B 89  ? 0.9521 0.7541 0.7777 -0.0690 -0.0611 -0.0473 304 ALA B C   
2282 O O   . ALA B 89  ? 0.8977 0.7116 0.7042 -0.0783 -0.0587 -0.0679 304 ALA B O   
2283 C CB  . ALA B 89  ? 0.8941 0.7402 0.7354 -0.0463 -0.0599 -0.0148 304 ALA B CB  
2284 N N   . ASP B 90  ? 0.9506 0.7444 0.7839 -0.0813 -0.0675 -0.0387 305 ASP B N   
2285 C CA  . ASP B 90  ? 0.9521 0.7563 0.7757 -0.1098 -0.0737 -0.0499 305 ASP B CA  
2286 C C   . ASP B 90  ? 0.9127 0.7819 0.7382 -0.1137 -0.0837 -0.0391 305 ASP B C   
2287 O O   . ASP B 90  ? 0.9132 0.8074 0.7580 -0.1024 -0.0884 -0.0190 305 ASP B O   
2288 C CB  . ASP B 90  ? 0.9597 0.7383 0.7923 -0.1257 -0.0751 -0.0408 305 ASP B CB  
2289 C CG  . ASP B 90  ? 0.9965 0.7855 0.8221 -0.1627 -0.0802 -0.0543 305 ASP B CG  
2290 O OD1 . ASP B 90  ? 1.0053 0.8293 0.8198 -0.1737 -0.0848 -0.0726 305 ASP B OD1 
2291 O OD2 . ASP B 90  ? 1.0134 0.7813 0.8435 -0.1842 -0.0800 -0.0456 305 ASP B OD2 
2292 N N   . LEU B 91  ? 0.9397 0.8393 0.7462 -0.1270 -0.0883 -0.0536 306 LEU B N   
2293 C CA  . LEU B 91  ? 0.9238 0.8876 0.7301 -0.1262 -0.1016 -0.0390 306 LEU B CA  
2294 C C   . LEU B 91  ? 0.9334 0.9405 0.7358 -0.1547 -0.1124 -0.0540 306 LEU B C   
2295 O O   . LEU B 91  ? 0.9590 1.0252 0.7520 -0.1568 -0.1254 -0.0497 306 LEU B O   
2296 C CB  . LEU B 91  ? 0.8935 0.8767 0.6772 -0.1167 -0.1010 -0.0341 306 LEU B CB  
2297 C CG  . LEU B 91  ? 0.8851 0.8386 0.6767 -0.0938 -0.0908 -0.0176 306 LEU B CG  
2298 C CD1 . LEU B 91  ? 0.8842 0.8669 0.6528 -0.0920 -0.0904 -0.0053 306 LEU B CD1 
2299 C CD2 . LEU B 91  ? 0.8717 0.8211 0.6943 -0.0765 -0.0971 0.0071  306 LEU B CD2 
2300 N N   . ASN B 92  ? 0.9571 0.9383 0.7659 -0.1789 -0.1086 -0.0694 307 ASN B N   
2301 C CA  . ASN B 92  ? 0.9691 0.9910 0.7778 -0.2146 -0.1173 -0.0872 307 ASN B CA  
2302 C C   . ASN B 92  ? 0.9421 0.9913 0.7807 -0.2225 -0.1196 -0.0710 307 ASN B C   
2303 O O   . ASN B 92  ? 0.9445 0.9474 0.7883 -0.2397 -0.1103 -0.0706 307 ASN B O   
2304 C CB  . ASN B 92  ? 1.0282 0.9924 0.8196 -0.2446 -0.1097 -0.1217 307 ASN B CB  
2305 C CG  . ASN B 92  ? 1.0744 1.0853 0.8605 -0.2866 -0.1195 -0.1486 307 ASN B CG  
2306 O OD1 . ASN B 92  ? 1.0916 1.1371 0.8554 -0.2952 -0.1253 -0.1738 307 ASN B OD1 
2307 N ND2 . ASN B 92  ? 1.0628 1.0845 0.8688 -0.3168 -0.1213 -0.1444 307 ASN B ND2 
2308 N N   . TRP B 93  ? 0.8994 1.0267 0.7578 -0.2089 -0.1321 -0.0569 308 TRP B N   
2309 C CA  . TRP B 93  ? 0.9051 1.0724 0.7957 -0.2116 -0.1317 -0.0463 308 TRP B CA  
2310 C C   . TRP B 93  ? 0.9036 1.1767 0.8173 -0.2215 -0.1472 -0.0509 308 TRP B C   
2311 O O   . TRP B 93  ? 0.8952 1.2110 0.7971 -0.2318 -0.1605 -0.0621 308 TRP B O   
2312 C CB  . TRP B 93  ? 0.8562 1.0075 0.7633 -0.1697 -0.1277 -0.0248 308 TRP B CB  
2313 C CG  . TRP B 93  ? 0.8491 1.0450 0.7708 -0.1321 -0.1423 -0.0114 308 TRP B CG  
2314 C CD1 . TRP B 93  ? 0.8112 1.0803 0.7673 -0.1136 -0.1539 -0.0068 308 TRP B CD1 
2315 C CD2 . TRP B 93  ? 0.8842 1.0514 0.7881 -0.1076 -0.1472 0.0013  308 TRP B CD2 
2316 N NE1 . TRP B 93  ? 0.8118 1.0873 0.7726 -0.0767 -0.1683 0.0100  308 TRP B NE1 
2317 C CE2 . TRP B 93  ? 0.8463 1.0598 0.7730 -0.0762 -0.1640 0.0181  308 TRP B CE2 
2318 C CE3 . TRP B 93  ? 0.8963 1.0068 0.7685 -0.1096 -0.1387 0.0002  308 TRP B CE3 
2319 C CZ2 . TRP B 93  ? 0.8590 1.0540 0.7739 -0.0516 -0.1731 0.0403  308 TRP B CZ2 
2320 C CZ3 . TRP B 93  ? 0.8901 0.9974 0.7507 -0.0877 -0.1451 0.0191  308 TRP B CZ3 
2321 C CH2 . TRP B 93  ? 0.8656 1.0100 0.7454 -0.0615 -0.1625 0.0421  308 TRP B CH2 
2322 N N   . SER B 108 ? 1.0628 1.6357 1.0974 0.0204  -0.2738 0.0576  323 SER B N   
2323 C CA  . SER B 108 ? 1.0924 1.7752 1.1733 0.0212  -0.2827 0.0363  323 SER B CA  
2324 C C   . SER B 108 ? 1.1259 1.8137 1.2595 0.0560  -0.2748 0.0254  323 SER B C   
2325 O O   . SER B 108 ? 1.0212 1.7922 1.1911 0.0447  -0.2687 -0.0006 323 SER B O   
2326 C CB  . SER B 108 ? 1.0968 1.8152 1.1627 -0.0419 -0.2668 0.0054  323 SER B CB  
2327 N N   . GLY B 109 ? 1.0443 1.6476 1.1815 0.0946  -0.2737 0.0424  324 GLY B N   
2328 C CA  . GLY B 109 ? 0.9881 1.5886 1.1713 0.1275  -0.2650 0.0253  324 GLY B CA  
2329 C C   . GLY B 109 ? 1.0005 1.5538 1.1691 0.0944  -0.2325 0.0055  324 GLY B C   
2330 O O   . GLY B 109 ? 0.9805 1.4740 1.1030 0.0544  -0.2173 0.0106  324 GLY B O   
2331 N N   . GLY B 110 ? 0.8404 1.4265 1.0500 0.1147  -0.2227 -0.0184 325 GLY B N   
2332 C CA  . GLY B 110 ? 0.7191 1.2790 0.9191 0.0893  -0.1947 -0.0356 325 GLY B CA  
2333 C C   . GLY B 110 ? 0.6637 1.1525 0.8752 0.1257  -0.1901 -0.0398 325 GLY B C   
2334 O O   . GLY B 110 ? 0.6828 1.1322 0.9116 0.1686  -0.2078 -0.0290 325 GLY B O   
2335 N N   . PHE B 111 ? 0.5573 1.3039 0.7292 0.0838  -0.0569 0.0017  326 PHE B N   
2336 C CA  . PHE B 111 ? 0.5634 1.2415 0.7208 0.1137  -0.0528 0.0019  326 PHE B CA  
2337 C C   . PHE B 111 ? 0.6040 1.1735 0.7423 0.0878  -0.0491 0.0157  326 PHE B C   
2338 O O   . PHE B 111 ? 0.6039 1.1634 0.7410 0.0434  -0.0424 0.0254  326 PHE B O   
2339 C CB  . PHE B 111 ? 0.5216 1.2572 0.6885 0.1147  -0.0422 -0.0045 326 PHE B CB  
2340 C CG  . PHE B 111 ? 0.5139 1.1739 0.6636 0.1313  -0.0375 -0.0041 326 PHE B CG  
2341 C CD1 . PHE B 111 ? 0.5317 1.1588 0.6711 0.1831  -0.0430 -0.0165 326 PHE B CD1 
2342 C CD2 . PHE B 111 ? 0.5501 1.1671 0.6905 0.0949  -0.0289 0.0082  326 PHE B CD2 
2343 C CE1 . PHE B 111 ? 0.5520 1.1108 0.6753 0.1932  -0.0393 -0.0192 326 PHE B CE1 
2344 C CE2 . PHE B 111 ? 0.5746 1.1309 0.7007 0.1091  -0.0265 0.0067  326 PHE B CE2 
2345 C CZ  . PHE B 111 ? 0.5565 1.0866 0.6757 0.1556  -0.0313 -0.0083 326 PHE B CZ  
2346 N N   . TYR B 112 ? 0.5807 1.0697 0.7022 0.1160  -0.0535 0.0165  327 TYR B N   
2347 C CA  . TYR B 112 ? 0.6539 1.0484 0.7600 0.0986  -0.0502 0.0264  327 TYR B CA  
2348 C C   . TYR B 112 ? 0.5799 0.9359 0.6802 0.1117  -0.0447 0.0236  327 TYR B C   
2349 O O   . TYR B 112 ? 0.5392 0.8877 0.6339 0.1482  -0.0473 0.0137  327 TYR B O   
2350 C CB  . TYR B 112 ? 0.6653 1.0024 0.7558 0.1147  -0.0570 0.0291  327 TYR B CB  
2351 C CG  . TYR B 112 ? 0.6649 1.0323 0.7572 0.0972  -0.0632 0.0313  327 TYR B CG  
2352 C CD1 . TYR B 112 ? 0.6574 1.1096 0.7618 0.1097  -0.0711 0.0240  327 TYR B CD1 
2353 C CD2 . TYR B 112 ? 0.6783 0.9964 0.7608 0.0680  -0.0617 0.0380  327 TYR B CD2 
2354 C CE1 . TYR B 112 ? 0.6765 1.1637 0.7830 0.0910  -0.0782 0.0234  327 TYR B CE1 
2355 C CE2 . TYR B 112 ? 0.6961 1.0415 0.7775 0.0502  -0.0680 0.0368  327 TYR B CE2 
2356 C CZ  . TYR B 112 ? 0.6863 1.1172 0.7799 0.0599  -0.0766 0.0294  327 TYR B CZ  
2357 O OH  . TYR B 112 ? 0.7295 1.1965 0.8229 0.0401  -0.0844 0.0255  327 TYR B OH  
2358 N N   . GLY B 113 ? 0.6286 0.9573 0.7269 0.0835  -0.0383 0.0314  328 GLY B N   
2359 C CA  . GLY B 113 ? 0.6476 0.9595 0.7420 0.0923  -0.0342 0.0273  328 GLY B CA  
2360 C C   . GLY B 113 ? 0.6589 0.9077 0.7455 0.0732  -0.0320 0.0360  328 GLY B C   
2361 O O   . GLY B 113 ? 0.6244 0.8498 0.7084 0.0484  -0.0316 0.0467  328 GLY B O   
2362 N N   . VAL B 114 ? 0.6131 0.8380 0.6954 0.0867  -0.0311 0.0289  329 VAL B N   
2363 C CA  . VAL B 114 ? 0.6771 0.8553 0.7550 0.0754  -0.0305 0.0332  329 VAL B CA  
2364 C C   . VAL B 114 ? 0.6225 0.8258 0.6972 0.0780  -0.0290 0.0290  329 VAL B C   
2365 O O   . VAL B 114 ? 0.5563 0.7804 0.6299 0.0987  -0.0290 0.0145  329 VAL B O   
2366 C CB  . VAL B 114 ? 0.6526 0.7749 0.7277 0.0873  -0.0319 0.0259  329 VAL B CB  
2367 C CG1 . VAL B 114 ? 0.6746 0.7650 0.7507 0.0758  -0.0315 0.0279  329 VAL B CG1 
2368 C CG2 . VAL B 114 ? 0.6965 0.7980 0.7693 0.0871  -0.0330 0.0307  329 VAL B CG2 
2369 N N   . SER B 115 ? 0.6759 0.8749 0.7448 0.0595  -0.0284 0.0413  330 SER B N   
2370 C CA  . SER B 115 ? 0.6716 0.8939 0.7320 0.0607  -0.0280 0.0405  330 SER B CA  
2371 C C   . SER B 115 ? 0.6689 0.8516 0.7255 0.0595  -0.0328 0.0428  330 SER B C   
2372 O O   . SER B 115 ? 0.6653 0.8133 0.7211 0.0490  -0.0344 0.0543  330 SER B O   
2373 C CB  . SER B 115 ? 0.6397 0.9018 0.6897 0.0401  -0.0232 0.0564  330 SER B CB  
2374 O OG  . SER B 115 ? 0.5665 0.8844 0.6244 0.0404  -0.0182 0.0515  330 SER B OG  
2375 N N   . SER B 116 ? 0.5934 0.7856 0.6478 0.0718  -0.0356 0.0294  331 SER B N   
2376 C CA  . SER B 116 ? 0.6661 0.8380 0.7196 0.0724  -0.0418 0.0284  331 SER B CA  
2377 C C   . SER B 116 ? 0.7050 0.9118 0.7436 0.0762  -0.0449 0.0276  331 SER B C   
2378 O O   . SER B 116 ? 0.6559 0.8981 0.6888 0.0835  -0.0418 0.0165  331 SER B O   
2379 C CB  . SER B 116 ? 0.6823 0.8291 0.7483 0.0801  -0.0438 0.0086  331 SER B CB  
2380 O OG  . SER B 116 ? 0.7395 0.8526 0.8145 0.0759  -0.0405 0.0117  331 SER B OG  
2381 N N   . GLN B 117 ? 0.6990 0.8981 0.7290 0.0745  -0.0515 0.0383  332 GLN B N   
2382 C CA  . GLN B 117 ? 0.7317 0.9642 0.7436 0.0801  -0.0563 0.0377  332 GLN B CA  
2383 C C   . GLN B 117 ? 0.7299 0.9533 0.7451 0.0880  -0.0677 0.0342  332 GLN B C   
2384 O O   . GLN B 117 ? 0.7641 0.9588 0.7804 0.0876  -0.0714 0.0487  332 GLN B O   
2385 C CB  . GLN B 117 ? 0.7267 0.9742 0.7115 0.0689  -0.0525 0.0638  332 GLN B CB  
2386 C CG  . GLN B 117 ? 0.7578 1.0414 0.7170 0.0752  -0.0572 0.0658  332 GLN B CG  
2387 C CD  . GLN B 117 ? 0.7549 1.0675 0.6868 0.0608  -0.0480 0.0856  332 GLN B CD  
2388 O OE1 . GLN B 117 ? 0.7253 1.0464 0.6635 0.0464  -0.0372 0.0907  332 GLN B OE1 
2389 N NE2 . GLN B 117 ? 0.8288 1.1618 0.7289 0.0629  -0.0521 0.0973  332 GLN B NE2 
2390 N N   . TYR B 118 ? 0.7197 0.9696 0.7370 0.0961  -0.0737 0.0123  333 TYR B N   
2391 C CA  . TYR B 118 ? 0.7632 1.0227 0.7855 0.1034  -0.0862 0.0057  333 TYR B CA  
2392 C C   . TYR B 118 ? 0.7688 1.0693 0.7653 0.1116  -0.0946 0.0066  333 TYR B C   
2393 O O   . TYR B 118 ? 0.7611 1.0849 0.7400 0.1106  -0.0889 0.0039  333 TYR B O   
2394 C CB  . TYR B 118 ? 0.7549 1.0126 0.8038 0.1003  -0.0877 -0.0246 333 TYR B CB  
2395 C CG  . TYR B 118 ? 0.7417 0.9595 0.8107 0.0915  -0.0784 -0.0262 333 TYR B CG  
2396 C CD1 . TYR B 118 ? 0.7300 0.9284 0.7981 0.0884  -0.0689 -0.0336 333 TYR B CD1 
2397 C CD2 . TYR B 118 ? 0.7337 0.9362 0.8204 0.0894  -0.0796 -0.0214 333 TYR B CD2 
2398 C CE1 . TYR B 118 ? 0.7389 0.8996 0.8202 0.0818  -0.0615 -0.0332 333 TYR B CE1 
2399 C CE2 . TYR B 118 ? 0.7259 0.8949 0.8270 0.0806  -0.0704 -0.0227 333 TYR B CE2 
2400 C CZ  . TYR B 118 ? 0.7351 0.8813 0.8317 0.0760  -0.0618 -0.0272 333 TYR B CZ  
2401 O OH  . TYR B 118 ? 0.7406 0.8523 0.8461 0.0687  -0.0538 -0.0262 333 TYR B OH  
2402 N N   . GLU B 119 ? 0.7680 1.0828 0.7615 0.1221  -0.1083 0.0094  334 GLU B N   
2403 C CA  . GLU B 119 ? 0.8167 1.1722 0.7819 0.1325  -0.1191 0.0116  334 GLU B CA  
2404 C C   . GLU B 119 ? 0.8185 1.2078 0.8001 0.1421  -0.1352 -0.0106 334 GLU B C   
2405 O O   . GLU B 119 ? 0.7932 1.1740 0.7973 0.1472  -0.1409 -0.0100 334 GLU B O   
2406 C CB  . GLU B 119 ? 0.8481 1.1874 0.7767 0.1390  -0.1224 0.0504  334 GLU B CB  
2407 C CG  . GLU B 119 ? 0.8716 1.2140 0.7700 0.1266  -0.1095 0.0674  334 GLU B CG  
2408 C CD  . GLU B 119 ? 0.9253 1.2412 0.7806 0.1256  -0.1108 0.1083  334 GLU B CD  
2409 O OE1 . GLU B 119 ? 0.9534 1.2736 0.7837 0.1434  -0.1262 0.1206  334 GLU B OE1 
2410 O OE2 . GLU B 119 ? 0.9220 1.2135 0.7655 0.1065  -0.0969 0.1279  334 GLU B OE2 
2411 N N   . SER B 120 ? 0.8442 1.2785 0.8144 0.1444  -0.1426 -0.0319 335 SER B N   
2412 C CA  . SER B 120 ? 0.8391 1.3170 0.8244 0.1503  -0.1594 -0.0559 335 SER B CA  
2413 C C   . SER B 120 ? 0.8754 1.4035 0.8255 0.1629  -0.1728 -0.0567 335 SER B C   
2414 O O   . SER B 120 ? 0.8787 1.4097 0.7945 0.1633  -0.1661 -0.0456 335 SER B O   
2415 C CB  . SER B 120 ? 0.8417 1.3232 0.8580 0.1318  -0.1557 -0.0967 335 SER B CB  
2416 O OG  . SER B 120 ? 0.8466 1.3762 0.8821 0.1320  -0.1718 -0.1193 335 SER B OG  
2417 N N   . LEU B 121 ? 0.8098 1.3855 0.7694 0.1728  -0.1919 -0.0718 336 LEU B N   
2418 C CA  . LEU B 121 ? 0.8009 1.4338 0.7295 0.1850  -0.2080 -0.0794 336 LEU B CA  
2419 C C   . LEU B 121 ? 0.7979 1.4695 0.7393 0.1691  -0.2116 -0.1281 336 LEU B C   
2420 O O   . LEU B 121 ? 0.7925 1.5101 0.7037 0.1758  -0.2221 -0.1400 336 LEU B O   
2421 C CB  . LEU B 121 ? 0.7756 1.4445 0.7015 0.2106  -0.2306 -0.0656 336 LEU B CB  
2422 C CG  . LEU B 121 ? 0.8219 1.4573 0.7049 0.2340  -0.2336 -0.0156 336 LEU B CG  
2423 C CD1 . LEU B 121 ? 0.8114 1.4655 0.7078 0.2622  -0.2534 -0.0073 336 LEU B CD1 
2424 C CD2 . LEU B 121 ? 0.8428 1.5040 0.6672 0.2430  -0.2396 -0.0006 336 LEU B CD2 
2425 N N   . GLU B 122 ? 0.8014 1.4515 0.7817 0.1471  -0.2033 -0.1564 337 GLU B N   
2426 C CA  . GLU B 122 ? 0.8003 1.4675 0.7875 0.1276  -0.2048 -0.2035 337 GLU B CA  
2427 C C   . GLU B 122 ? 0.8298 1.4373 0.8108 0.1161  -0.1840 -0.2115 337 GLU B C   
2428 O O   . GLU B 122 ? 0.8181 1.3733 0.8128 0.1132  -0.1692 -0.1907 337 GLU B O   
2429 C CB  . GLU B 122 ? 0.7878 1.4754 0.8189 0.1077  -0.2121 -0.2322 337 GLU B CB  
2430 C CG  . GLU B 122 ? 0.8746 1.5189 0.9379 0.1029  -0.2000 -0.2112 337 GLU B CG  
2431 C CD  . GLU B 122 ? 0.8539 1.5474 0.9560 0.0995  -0.2116 -0.2202 337 GLU B CD  
2432 O OE1 . GLU B 122 ? 0.8501 1.5985 0.9469 0.1255  -0.2296 -0.2071 337 GLU B OE1 
2433 O OE2 . GLU B 122 ? 0.8117 1.4879 0.9475 0.0729  -0.2019 -0.2377 337 GLU B OE2 
2434 N N   . HIS B 123 ? 0.7983 1.4168 0.7557 0.1134  -0.1841 -0.2421 338 HIS B N   
2435 C CA  . HIS B 123 ? 0.8134 1.3805 0.7616 0.1096  -0.1667 -0.2555 338 HIS B CA  
2436 C C   . HIS B 123 ? 0.8112 1.3249 0.7885 0.0864  -0.1609 -0.2798 338 HIS B C   
2437 O O   . HIS B 123 ? 0.8088 1.3335 0.7942 0.0672  -0.1703 -0.3162 338 HIS B O   
2438 C CB  . HIS B 123 ? 0.8112 1.4063 0.7241 0.1165  -0.1700 -0.2873 338 HIS B CB  
2439 C CG  . HIS B 123 ? 0.8329 1.3829 0.7318 0.1225  -0.1532 -0.3012 338 HIS B CG  
2440 N ND1 . HIS B 123 ? 0.8480 1.4172 0.7194 0.1420  -0.1426 -0.2862 338 HIS B ND1 
2441 C CD2 . HIS B 123 ? 0.8583 1.3440 0.7669 0.1134  -0.1447 -0.3258 338 HIS B CD2 
2442 C CE1 . HIS B 123 ? 0.8573 1.3856 0.7246 0.1487  -0.1299 -0.3057 338 HIS B CE1 
2443 N NE2 . HIS B 123 ? 0.8857 1.3564 0.7728 0.1333  -0.1316 -0.3284 338 HIS B NE2 
2444 N N   . MET B 124 ? 0.8362 1.2928 0.8265 0.0853  -0.1455 -0.2597 339 MET B N   
2445 C CA  . MET B 124 ? 0.8458 1.2429 0.8559 0.0639  -0.1380 -0.2767 339 MET B CA  
2446 C C   . MET B 124 ? 0.8550 1.1907 0.8511 0.0744  -0.1224 -0.2728 339 MET B C   
2447 O O   . MET B 124 ? 0.8315 1.1794 0.8114 0.0961  -0.1162 -0.2541 339 MET B O   
2448 C CB  . MET B 124 ? 0.8298 1.2204 0.8748 0.0515  -0.1362 -0.2547 339 MET B CB  
2449 C CG  . MET B 124 ? 0.8304 1.2812 0.8976 0.0404  -0.1511 -0.2644 339 MET B CG  
2450 S SD  . MET B 124 ? 0.8420 1.2977 0.9441 0.0427  -0.1479 -0.2295 339 MET B SD  
2451 C CE  . MET B 124 ? 0.8193 1.2475 0.8990 0.0717  -0.1394 -0.1842 339 MET B CE  
2452 N N   . THR B 125 ? 0.8741 1.1454 0.8752 0.0582  -0.1160 -0.2902 340 THR B N   
2453 C CA  . THR B 125 ? 0.9154 1.1230 0.9093 0.0692  -0.1025 -0.2792 340 THR B CA  
2454 C C   . THR B 125 ? 0.9125 1.0857 0.9324 0.0515  -0.0961 -0.2577 340 THR B C   
2455 O O   . THR B 125 ? 0.9141 1.0820 0.9500 0.0237  -0.0990 -0.2704 340 THR B O   
2456 C CB  . THR B 125 ? 0.9658 1.1128 0.9328 0.0710  -0.1002 -0.3149 340 THR B CB  
2457 O OG1 . THR B 125 ? 0.9698 1.1477 0.9107 0.0982  -0.1016 -0.3291 340 THR B OG1 
2458 C CG2 . THR B 125 ? 0.9937 1.0644 0.9566 0.0782  -0.0886 -0.3020 340 THR B CG2 
2459 N N   . LEU B 126 ? 0.9116 1.0687 0.9359 0.0657  -0.0870 -0.2267 341 LEU B N   
2460 C CA  . LEU B 126 ? 0.8967 1.0327 0.9438 0.0530  -0.0809 -0.2026 341 LEU B CA  
2461 C C   . LEU B 126 ? 0.9159 0.9778 0.9525 0.0541  -0.0705 -0.1999 341 LEU B C   
2462 O O   . LEU B 126 ? 0.8887 0.9288 0.9049 0.0768  -0.0673 -0.2024 341 LEU B O   
2463 C CB  . LEU B 126 ? 0.8495 1.0244 0.9071 0.0664  -0.0804 -0.1679 341 LEU B CB  
2464 C CG  . LEU B 126 ? 0.8280 1.0674 0.8911 0.0696  -0.0915 -0.1607 341 LEU B CG  
2465 C CD1 . LEU B 126 ? 0.7923 1.0414 0.8636 0.0774  -0.0894 -0.1244 341 LEU B CD1 
2466 C CD2 . LEU B 126 ? 0.8320 1.0959 0.9122 0.0509  -0.1007 -0.1824 341 LEU B CD2 
2467 N N   . THR B 127 ? 0.9110 0.9380 0.9599 0.0308  -0.0654 -0.1962 342 THR B N   
2468 C CA  . THR B 127 ? 0.9433 0.9035 0.9822 0.0313  -0.0555 -0.1835 342 THR B CA  
2469 C C   . THR B 127 ? 0.9155 0.8953 0.9771 0.0287  -0.0506 -0.1530 342 THR B C   
2470 O O   . THR B 127 ? 0.8516 0.8660 0.9369 0.0111  -0.0518 -0.1506 342 THR B O   
2471 C CB  . THR B 127 ? 0.9761 0.8708 1.0024 0.0026  -0.0515 -0.2026 342 THR B CB  
2472 O OG1 . THR B 127 ? 1.0006 0.8848 1.0084 -0.0017 -0.0582 -0.2363 342 THR B OG1 
2473 C CG2 . THR B 127 ? 0.9858 0.7978 0.9862 0.0112  -0.0431 -0.1907 342 THR B CG2 
2474 N N   . CYS B 128 ? 0.9022 0.8663 0.9568 0.0481  -0.0461 -0.1321 343 CYS B N   
2475 C CA  A CYS B 128 ? 0.8621 0.8341 0.9322 0.0457  -0.0412 -0.1059 343 CYS B CA  
2476 C CA  B CYS B 128 ? 0.8449 0.8166 0.9151 0.0454  -0.0411 -0.1059 343 CYS B CA  
2477 C C   . CYS B 128 ? 0.8767 0.7855 0.9321 0.0428  -0.0331 -0.0982 343 CYS B C   
2478 O O   . CYS B 128 ? 0.8921 0.7708 0.9265 0.0634  -0.0329 -0.0967 343 CYS B O   
2479 C CB  A CYS B 128 ? 0.8185 0.8304 0.8909 0.0660  -0.0436 -0.0876 343 CYS B CB  
2480 C CB  B CYS B 128 ? 0.8658 0.8767 0.9393 0.0651  -0.0432 -0.0862 343 CYS B CB  
2481 S SG  A CYS B 128 ? 0.8242 0.8972 0.8956 0.0748  -0.0528 -0.0970 343 CYS B SG  
2482 S SG  B CYS B 128 ? 0.8276 0.8382 0.9157 0.0592  -0.0379 -0.0581 343 CYS B SG  
2483 N N   . SER B 129 ? 0.8849 0.7781 0.9495 0.0193  -0.0266 -0.0935 344 SER B N   
2484 C CA  . SER B 129 ? 0.8871 0.7211 0.9340 0.0124  -0.0179 -0.0830 344 SER B CA  
2485 C C   . SER B 129 ? 0.8587 0.7145 0.9196 0.0141  -0.0136 -0.0604 344 SER B C   
2486 O O   . SER B 129 ? 0.8294 0.7275 0.9152 0.0029  -0.0127 -0.0588 344 SER B O   
2487 C CB  . SER B 129 ? 0.9033 0.7031 0.9455 -0.0217 -0.0113 -0.0964 344 SER B CB  
2488 O OG  . SER B 129 ? 0.9614 0.7361 0.9997 -0.0366 -0.0006 -0.0800 344 SER B OG  
2489 N N   . SER B 130 ? 0.8705 0.7004 0.9145 0.0307  -0.0122 -0.0451 345 SER B N   
2490 C CA  . SER B 130 ? 0.8670 0.7120 0.9189 0.0316  -0.0087 -0.0263 345 SER B CA  
2491 C C   . SER B 130 ? 0.9398 0.7311 0.9685 0.0226  -0.0003 -0.0172 345 SER B C   
2492 O O   . SER B 130 ? 0.9556 0.7016 0.9555 0.0373  -0.0020 -0.0139 345 SER B O   
2493 C CB  . SER B 130 ? 0.8446 0.7155 0.8961 0.0552  -0.0150 -0.0160 345 SER B CB  
2494 O OG  . SER B 130 ? 0.8386 0.7580 0.9071 0.0593  -0.0209 -0.0199 345 SER B OG  
2495 N N   . LYS B 131 ? 0.9144 0.7115 0.9527 0.0003  0.0089  -0.0134 346 LYS B N   
2496 C CA  . LYS B 131 ? 0.9980 0.7491 1.0119 -0.0135 0.0194  -0.0028 346 LYS B CA  
2497 C C   . LYS B 131 ? 0.9694 0.7408 0.9856 -0.0060 0.0217  0.0123  346 LYS B C   
2498 O O   . LYS B 131 ? 0.9045 0.7185 0.9457 -0.0136 0.0249  0.0102  346 LYS B O   
2499 C CB  . LYS B 131 ? 1.0140 0.7640 1.0359 -0.0491 0.0309  -0.0122 346 LYS B CB  
2500 C CG  . LYS B 131 ? 1.0830 0.8041 1.0971 -0.0656 0.0301  -0.0293 346 LYS B CG  
2501 C CD  . LYS B 131 ? 1.1883 0.8879 1.1951 -0.1072 0.0451  -0.0322 346 LYS B CD  
2502 C CE  . LYS B 131 ? 1.2567 0.9894 1.2884 -0.1341 0.0445  -0.0567 346 LYS B CE  
2503 N NZ  . LYS B 131 ? 1.2207 0.9237 1.2391 -0.1206 0.0320  -0.0717 346 LYS B NZ  
2504 N N   . VAL B 132 ? 0.9596 0.7022 0.9488 0.0115  0.0185  0.0255  347 VAL B N   
2505 C CA  . VAL B 132 ? 0.9912 0.7499 0.9773 0.0167  0.0196  0.0377  347 VAL B CA  
2506 C C   . VAL B 132 ? 1.0345 0.7582 0.9951 -0.0014 0.0325  0.0469  347 VAL B C   
2507 O O   . VAL B 132 ? 1.0038 0.6710 0.9289 -0.0018 0.0347  0.0546  347 VAL B O   
2508 C CB  . VAL B 132 ? 0.9651 0.7253 0.9373 0.0443  0.0081  0.0457  347 VAL B CB  
2509 C CG1 . VAL B 132 ? 0.9401 0.7129 0.9039 0.0456  0.0088  0.0562  347 VAL B CG1 
2510 C CG2 . VAL B 132 ? 0.9272 0.7308 0.9247 0.0566  -0.0016 0.0375  347 VAL B CG2 
2511 N N   . CYS B 133 ? 1.0213 0.7760 0.9962 -0.0153 0.0414  0.0462  348 CYS B N   
2512 C CA  . CYS B 133 ? 1.0277 0.7647 0.9833 -0.0376 0.0571  0.0526  348 CYS B CA  
2513 C C   . CYS B 133 ? 1.0222 0.7702 0.9631 -0.0291 0.0585  0.0621  348 CYS B C   
2514 O O   . CYS B 133 ? 0.9345 0.7206 0.8962 -0.0175 0.0523  0.0564  348 CYS B O   
2515 C CB  . CYS B 133 ? 1.0379 0.8143 1.0251 -0.0627 0.0690  0.0385  348 CYS B CB  
2516 S SG  . CYS B 133 ? 1.0779 0.8489 1.0819 -0.0801 0.0677  0.0234  348 CYS B SG  
2517 N N   . SER B 134 ? 1.0848 0.7953 0.9855 -0.0367 0.0669  0.0764  349 SER B N   
2518 C CA  . SER B 134 ? 1.0445 0.7651 0.9248 -0.0302 0.0686  0.0846  349 SER B CA  
2519 C C   . SER B 134 ? 1.0908 0.8069 0.9529 -0.0578 0.0896  0.0890  349 SER B C   
2520 O O   . SER B 134 ? 1.1338 0.7999 0.9607 -0.0737 0.0983  0.1022  349 SER B O   
2521 C CB  . SER B 134 ? 1.0686 0.7543 0.9103 -0.0065 0.0556  0.1003  349 SER B CB  
2522 O OG  . SER B 134 ? 1.0796 0.7693 0.8920 -0.0053 0.0590  0.1095  349 SER B OG  
2523 N N   . PHE B 135 ? 1.0425 0.8081 0.9249 -0.0638 0.0987  0.0779  350 PHE B N   
2524 C CA  . PHE B 135 ? 1.0670 0.8460 0.9396 -0.0917 0.1214  0.0781  350 PHE B CA  
2525 C C   . PHE B 135 ? 1.1226 0.9047 1.0167 -0.1199 0.1322  0.0710  350 PHE B C   
2526 O O   . PHE B 135 ? 1.1378 0.9010 1.0082 -0.1512 0.1500  0.0792  350 PHE B O   
2527 C CB  . PHE B 135 ? 1.0888 0.8216 0.9010 -0.0977 0.1283  0.1009  350 PHE B CB  
2528 C CG  . PHE B 135 ? 1.0650 0.8158 0.8574 -0.0787 0.1234  0.1027  350 PHE B CG  
2529 C CD1 . PHE B 135 ? 1.0561 0.8500 0.8491 -0.0882 0.1390  0.0933  350 PHE B CD1 
2530 C CD2 . PHE B 135 ? 1.0982 0.8345 0.8794 -0.0496 0.1013  0.1079  350 PHE B CD2 
2531 C CE1 . PHE B 135 ? 1.0150 0.8242 0.7885 -0.0706 0.1326  0.0906  350 PHE B CE1 
2532 C CE2 . PHE B 135 ? 1.0364 0.7940 0.8019 -0.0352 0.0946  0.1057  350 PHE B CE2 
2533 C CZ  . PHE B 135 ? 1.0001 0.7904 0.7604 -0.0458 0.1097  0.0964  350 PHE B CZ  
2534 N N   . GLY B 136 ? 1.2267 1.0327 1.1630 -0.1115 0.1212  0.0559  351 GLY B N   
2535 C CA  . GLY B 136 ? 1.2342 1.0503 1.1935 -0.1375 0.1280  0.0454  351 GLY B CA  
2536 C C   . GLY B 136 ? 1.2984 1.0421 1.2227 -0.1559 0.1290  0.0570  351 GLY B C   
2537 O O   . GLY B 136 ? 1.3482 1.0927 1.2805 -0.1897 0.1397  0.0493  351 GLY B O   
2538 N N   . LYS B 137 ? 1.2100 0.8910 1.0944 -0.1340 0.1173  0.0739  352 LYS B N   
2539 C CA  . LYS B 137 ? 1.2260 0.8236 1.0677 -0.1418 0.1157  0.0858  352 LYS B CA  
2540 C C   . LYS B 137 ? 1.1866 0.7677 1.0363 -0.1066 0.0936  0.0808  352 LYS B C   
2541 O O   . LYS B 137 ? 1.1454 0.7433 0.9971 -0.0730 0.0802  0.0851  352 LYS B O   
2542 C CB  . LYS B 137 ? 1.2511 0.7881 1.0298 -0.1410 0.1217  0.1122  352 LYS B CB  
2543 C CG  . LYS B 137 ? 1.3016 0.8270 1.0540 -0.1867 0.1473  0.1217  352 LYS B CG  
2544 C CD  . LYS B 137 ? 1.3350 0.8588 1.0474 -0.1799 0.1545  0.1414  352 LYS B CD  
2545 C CE  . LYS B 137 ? 1.3414 0.7786 0.9770 -0.2041 0.1684  0.1708  352 LYS B CE  
2546 N NZ  . LYS B 137 ? 1.3426 0.7336 0.9606 -0.2556 0.1870  0.1732  352 LYS B NZ  
2547 N N   . GLN B 138 ? 1.1695 0.7252 1.0255 -0.1161 0.0902  0.0692  353 GLN B N   
2548 C CA  . GLN B 138 ? 1.1306 0.6770 0.9937 -0.0826 0.0710  0.0619  353 GLN B CA  
2549 C C   . GLN B 138 ? 1.1693 0.6575 0.9852 -0.0496 0.0609  0.0803  353 GLN B C   
2550 O O   . GLN B 138 ? 1.2141 0.6274 0.9786 -0.0578 0.0668  0.0958  353 GLN B O   
2551 C CB  . GLN B 138 ? 1.1501 0.6678 1.0168 -0.0996 0.0700  0.0453  353 GLN B CB  
2552 C CG  . GLN B 138 ? 1.1482 0.6687 1.0250 -0.0643 0.0517  0.0342  353 GLN B CG  
2553 C CD  . GLN B 138 ? 1.1901 0.6696 1.0594 -0.0778 0.0495  0.0161  353 GLN B CD  
2554 O OE1 . GLN B 138 ? 1.2180 0.7370 1.1192 -0.1057 0.0536  -0.0021 353 GLN B OE1 
2555 N NE2 . GLN B 138 ? 1.2183 0.6202 1.0442 -0.0555 0.0419  0.0190  353 GLN B NE2 
2556 N N   . VAL B 139 ? 1.1210 0.6442 0.9516 -0.0126 0.0453  0.0795  354 VAL B N   
2557 C CA  . VAL B 139 ? 1.1633 0.6452 0.9526 0.0223  0.0340  0.0950  354 VAL B CA  
2558 C C   . VAL B 139 ? 1.1494 0.6279 0.9445 0.0554  0.0184  0.0839  354 VAL B C   
2559 O O   . VAL B 139 ? 1.1984 0.6234 0.9538 0.0848  0.0094  0.0919  354 VAL B O   
2560 C CB  . VAL B 139 ? 1.1539 0.6836 0.9468 0.0376  0.0294  0.1050  354 VAL B CB  
2561 C CG1 . VAL B 139 ? 1.1632 0.7021 0.9506 0.0062  0.0463  0.1121  354 VAL B CG1 
2562 C CG2 . VAL B 139 ? 1.0814 0.6871 0.9233 0.0497  0.0200  0.0910  354 VAL B CG2 
2563 N N   . VAL B 140 ? 1.1094 0.6458 0.9514 0.0531  0.0150  0.0656  355 VAL B N   
2564 C CA  . VAL B 140 ? 1.0963 0.6427 0.9482 0.0803  0.0028  0.0519  355 VAL B CA  
2565 C C   . VAL B 140 ? 1.0692 0.6448 0.9562 0.0580  0.0063  0.0321  355 VAL B C   
2566 O O   . VAL B 140 ? 1.0308 0.6571 0.9515 0.0359  0.0122  0.0291  355 VAL B O   
2567 C CB  . VAL B 140 ? 1.0607 0.6727 0.9328 0.1106  -0.0092 0.0534  355 VAL B CB  
2568 C CG1 . VAL B 140 ? 1.0938 0.7161 0.9703 0.1400  -0.0196 0.0394  355 VAL B CG1 
2569 C CG2 . VAL B 140 ? 1.0988 0.6911 0.9371 0.1318  -0.0143 0.0714  355 VAL B CG2 
2570 N N   . GLU B 141 ? 1.0841 0.6267 0.9603 0.0666  0.0018  0.0175  356 GLU B N   
2571 C CA  . GLU B 141 ? 1.0876 0.6653 0.9945 0.0530  0.0010  -0.0038 356 GLU B CA  
2572 C C   . GLU B 141 ? 1.0772 0.6737 0.9859 0.0883  -0.0108 -0.0162 356 GLU B C   
2573 O O   . GLU B 141 ? 1.1056 0.6514 0.9801 0.1165  -0.0164 -0.0171 356 GLU B O   
2574 C CB  . GLU B 141 ? 1.1245 0.6470 1.0158 0.0198  0.0089  -0.0156 356 GLU B CB  
2575 C CG  . GLU B 141 ? 1.0995 0.6678 1.0235 0.0043  0.0067  -0.0388 356 GLU B CG  
2576 C CD  . GLU B 141 ? 1.1571 0.6817 1.0696 -0.0353 0.0144  -0.0529 356 GLU B CD  
2577 O OE1 . GLU B 141 ? 1.2374 0.6715 1.1043 -0.0424 0.0185  -0.0495 356 GLU B OE1 
2578 O OE2 . GLU B 141 ? 1.1405 0.7212 1.0879 -0.0602 0.0160  -0.0675 356 GLU B OE2 
2579 N N   . LYS B 142 ? 1.0123 0.6811 0.9574 0.0885  -0.0144 -0.0257 357 LYS B N   
2580 C CA  . LYS B 142 ? 0.9939 0.6918 0.9430 0.1154  -0.0229 -0.0403 357 LYS B CA  
2581 C C   . LYS B 142 ? 0.9942 0.7146 0.9606 0.0966  -0.0230 -0.0604 357 LYS B C   
2582 O O   . LYS B 142 ? 0.9554 0.7182 0.9498 0.0731  -0.0203 -0.0583 357 LYS B O   
2583 C CB  . LYS B 142 ? 0.9599 0.7308 0.9309 0.1340  -0.0275 -0.0307 357 LYS B CB  
2584 C CG  . LYS B 142 ? 0.9797 0.8013 0.9614 0.1530  -0.0330 -0.0455 357 LYS B CG  
2585 C CD  . LYS B 142 ? 0.9812 0.8250 0.9536 0.1903  -0.0386 -0.0437 357 LYS B CD  
2586 C CE  . LYS B 142 ? 0.9951 0.8940 0.9756 0.2099  -0.0416 -0.0603 357 LYS B CE  
2587 N NZ  . LYS B 142 ? 1.0119 0.9459 0.9869 0.2487  -0.0465 -0.0621 357 LYS B NZ  
2588 N N   . VAL B 143 ? 0.9998 0.6936 0.9479 0.1100  -0.0273 -0.0812 358 VAL B N   
2589 C CA  . VAL B 143 ? 1.0146 0.7278 0.9737 0.0929  -0.0291 -0.1038 358 VAL B CA  
2590 C C   . VAL B 143 ? 1.0038 0.7588 0.9626 0.1234  -0.0361 -0.1185 358 VAL B C   
2591 O O   . VAL B 143 ? 1.0239 0.7510 0.9584 0.1561  -0.0391 -0.1243 358 VAL B O   
2592 C CB  . VAL B 143 ? 1.0483 0.6825 0.9803 0.0703  -0.0263 -0.1208 358 VAL B CB  
2593 C CG1 . VAL B 143 ? 1.0241 0.6922 0.9744 0.0432  -0.0284 -0.1438 358 VAL B CG1 
2594 C CG2 . VAL B 143 ? 1.0642 0.6463 0.9846 0.0447  -0.0170 -0.1028 358 VAL B CG2 
2595 N N   . GLU B 144 ? 0.9644 0.7883 0.9477 0.1152  -0.0387 -0.1242 359 GLU B N   
2596 C CA  . GLU B 144 ? 0.9358 0.8085 0.9176 0.1393  -0.0435 -0.1377 359 GLU B CA  
2597 C C   . GLU B 144 ? 0.9107 0.8129 0.8997 0.1214  -0.0475 -0.1573 359 GLU B C   
2598 O O   . GLU B 144 ? 0.9174 0.8324 0.9249 0.0931  -0.0475 -0.1530 359 GLU B O   
2599 C CB  . GLU B 144 ? 0.9070 0.8511 0.9083 0.1502  -0.0428 -0.1170 359 GLU B CB  
2600 C CG  . GLU B 144 ? 0.9191 0.8648 0.9119 0.1797  -0.0420 -0.1088 359 GLU B CG  
2601 C CD  . GLU B 144 ? 0.9649 0.9570 0.9786 0.1721  -0.0397 -0.0824 359 GLU B CD  
2602 O OE1 . GLU B 144 ? 0.9925 1.0242 1.0081 0.1922  -0.0398 -0.0772 359 GLU B OE1 
2603 O OE2 . GLU B 144 ? 0.9537 0.9455 0.9820 0.1456  -0.0380 -0.0690 359 GLU B OE2 
2604 N N   . THR B 145 ? 0.8985 0.8178 0.8727 0.1403  -0.0515 -0.1803 360 THR B N   
2605 C CA  . THR B 145 ? 0.8869 0.8493 0.8654 0.1282  -0.0570 -0.1988 360 THR B CA  
2606 C C   . THR B 145 ? 0.8656 0.9049 0.8464 0.1491  -0.0579 -0.1945 360 THR B C   
2607 O O   . THR B 145 ? 0.8588 0.9106 0.8308 0.1769  -0.0545 -0.1927 360 THR B O   
2608 C CB  . THR B 145 ? 0.9390 0.8514 0.8910 0.1261  -0.0609 -0.2357 360 THR B CB  
2609 O OG1 . THR B 145 ? 1.0084 0.9137 0.9357 0.1637  -0.0610 -0.2515 360 THR B OG1 
2610 C CG2 . THR B 145 ? 0.9825 0.8041 0.9219 0.1051  -0.0576 -0.2386 360 THR B CG2 
2611 N N   . GLU B 146 ? 0.8647 0.9589 0.8554 0.1359  -0.0626 -0.1934 361 GLU B N   
2612 C CA  . GLU B 146 ? 0.8525 1.0185 0.8401 0.1492  -0.0626 -0.1855 361 GLU B CA  
2613 C C   . GLU B 146 ? 0.8494 1.0536 0.8312 0.1395  -0.0713 -0.2017 361 GLU B C   
2614 O O   . GLU B 146 ? 0.8406 1.0449 0.8365 0.1185  -0.0774 -0.1987 361 GLU B O   
2615 C CB  . GLU B 146 ? 0.8177 1.0127 0.8225 0.1429  -0.0585 -0.1475 361 GLU B CB  
2616 C CG  . GLU B 146 ? 0.7872 1.0505 0.7857 0.1463  -0.0577 -0.1326 361 GLU B CG  
2617 C CD  . GLU B 146 ? 0.7890 1.0867 0.7765 0.1672  -0.0499 -0.1370 361 GLU B CD  
2618 O OE1 . GLU B 146 ? 0.7897 1.0628 0.7821 0.1798  -0.0454 -0.1384 361 GLU B OE1 
2619 O OE2 . GLU B 146 ? 0.7723 1.1266 0.7454 0.1723  -0.0484 -0.1394 361 GLU B OE2 
2620 N N   . ARG B 147 ? 0.8493 1.0912 0.8102 0.1562  -0.0722 -0.2206 362 ARG B N   
2621 C CA  . ARG B 147 ? 0.8563 1.1405 0.8065 0.1495  -0.0817 -0.2373 362 ARG B CA  
2622 C C   . ARG B 147 ? 0.8038 1.1554 0.7515 0.1506  -0.0821 -0.2083 362 ARG B C   
2623 O O   . ARG B 147 ? 0.7861 1.1591 0.7327 0.1590  -0.0728 -0.1846 362 ARG B O   
2624 C CB  . ARG B 147 ? 0.9012 1.1873 0.8234 0.1662  -0.0833 -0.2778 362 ARG B CB  
2625 C CG  . ARG B 147 ? 0.9587 1.1649 0.8721 0.1719  -0.0813 -0.3045 362 ARG B CG  
2626 C CD  . ARG B 147 ? 1.0642 1.2636 0.9453 0.1908  -0.0838 -0.3482 362 ARG B CD  
2627 N NE  . ARG B 147 ? 1.1214 1.3951 0.9868 0.2166  -0.0797 -0.3517 362 ARG B NE  
2628 C CZ  . ARG B 147 ? 1.1301 1.4202 0.9902 0.2473  -0.0696 -0.3480 362 ARG B CZ  
2629 N NH1 . ARG B 147 ? 1.1186 1.3596 0.9891 0.2587  -0.0642 -0.3356 362 ARG B NH1 
2630 N NH2 . ARG B 147 ? 1.1020 1.4658 0.9453 0.2677  -0.0649 -0.3578 362 ARG B NH2 
2631 N N   . ALA B 148 ? 0.8025 1.1874 0.7468 0.1409  -0.0935 -0.2103 363 ALA B N   
2632 C CA  . ALA B 148 ? 0.8027 1.2378 0.7381 0.1417  -0.0958 -0.1784 363 ALA B CA  
2633 C C   . ALA B 148 ? 0.8082 1.2894 0.7162 0.1561  -0.0871 -0.1758 363 ALA B C   
2634 O O   . ALA B 148 ? 0.8183 1.3112 0.7106 0.1689  -0.0847 -0.2080 363 ALA B O   
2635 C CB  . ALA B 148 ? 0.8173 1.2850 0.7486 0.1356  -0.1123 -0.1852 363 ALA B CB  
2636 N N   . GLN B 149 ? 0.7830 1.2898 0.6830 0.1529  -0.0816 -0.1378 364 GLN B N   
2637 C CA  . GLN B 149 ? 0.7831 1.3480 0.6525 0.1593  -0.0740 -0.1298 364 GLN B CA  
2638 C C   . GLN B 149 ? 0.8001 1.3930 0.6450 0.1538  -0.0843 -0.1056 364 GLN B C   
2639 O O   . GLN B 149 ? 0.8192 1.3870 0.6701 0.1447  -0.0883 -0.0727 364 GLN B O   
2640 C CB  . GLN B 149 ? 0.7714 1.3441 0.6462 0.1558  -0.0572 -0.1049 364 GLN B CB  
2641 C CG  . GLN B 149 ? 0.7786 1.3598 0.6611 0.1731  -0.0469 -0.1342 364 GLN B CG  
2642 C CD  . GLN B 149 ? 0.7719 1.3594 0.6708 0.1695  -0.0334 -0.1137 364 GLN B CD  
2643 O OE1 . GLN B 149 ? 0.7710 1.4152 0.6622 0.1779  -0.0210 -0.1179 364 GLN B OE1 
2644 N NE2 . GLN B 149 ? 0.7500 1.2876 0.6718 0.1569  -0.0354 -0.0932 364 GLN B NE2 
2645 N N   . LEU B 150 ? 0.8166 1.4574 0.6315 0.1621  -0.0901 -0.1237 365 LEU B N   
2646 C CA  . LEU B 150 ? 0.8340 1.5073 0.6162 0.1615  -0.1010 -0.1000 365 LEU B CA  
2647 C C   . LEU B 150 ? 0.8456 1.5325 0.6015 0.1526  -0.0877 -0.0551 365 LEU B C   
2648 O O   . LEU B 150 ? 0.8290 1.5615 0.5621 0.1530  -0.0736 -0.0574 365 LEU B O   
2649 C CB  . LEU B 150 ? 0.8181 1.5451 0.5696 0.1724  -0.1088 -0.1319 365 LEU B CB  
2650 C CG  . LEU B 150 ? 0.8545 1.5933 0.6032 0.1756  -0.1326 -0.1468 365 LEU B CG  
2651 C CD1 . LEU B 150 ? 0.8635 1.6616 0.5765 0.1854  -0.1404 -0.1815 365 LEU B CD1 
2652 C CD2 . LEU B 150 ? 0.8749 1.6074 0.6124 0.1752  -0.1431 -0.1004 365 LEU B CD2 
2653 N N   . GLU B 151 ? 0.8873 1.5378 0.6417 0.1442  -0.0924 -0.0154 366 GLU B N   
2654 C CA  . GLU B 151 ? 0.8908 1.5382 0.6161 0.1292  -0.0802 0.0300  366 GLU B CA  
2655 C C   . GLU B 151 ? 0.9554 1.5822 0.6458 0.1319  -0.0952 0.0663  366 GLU B C   
2656 O O   . GLU B 151 ? 0.9943 1.5659 0.6967 0.1307  -0.1021 0.0879  366 GLU B O   
2657 C CB  . GLU B 151 ? 0.8796 1.4848 0.6373 0.1147  -0.0676 0.0425  366 GLU B CB  
2658 C CG  . GLU B 151 ? 0.8329 1.4715 0.6100 0.1150  -0.0514 0.0159  366 GLU B CG  
2659 C CD  . GLU B 151 ? 0.8056 1.4284 0.5994 0.0966  -0.0361 0.0368  366 GLU B CD  
2660 O OE1 . GLU B 151 ? 0.8240 1.3991 0.6147 0.0813  -0.0383 0.0700  366 GLU B OE1 
2661 O OE2 . GLU B 151 ? 0.7947 1.4570 0.6022 0.0986  -0.0223 0.0187  366 GLU B OE2 
2662 N N   . ASP B 152 ? 0.9799 1.6505 0.6237 0.1388  -0.1006 0.0722  367 ASP B N   
2663 C CA  . ASP B 152 ? 1.0764 1.7289 0.6729 0.1442  -0.1139 0.1126  367 ASP B CA  
2664 C C   . ASP B 152 ? 1.0748 1.7145 0.6925 0.1671  -0.1401 0.0980  367 ASP B C   
2665 O O   . ASP B 152 ? 1.0781 1.6632 0.7155 0.1702  -0.1467 0.1145  367 ASP B O   
2666 C CB  . ASP B 152 ? 1.0979 1.6895 0.6774 0.1238  -0.1023 0.1609  367 ASP B CB  
2667 C CG  . ASP B 152 ? 1.2437 1.7924 0.7704 0.1331  -0.1176 0.2057  367 ASP B CG  
2668 O OD1 . ASP B 152 ? 1.2721 1.8076 0.8029 0.1602  -0.1414 0.2020  367 ASP B OD1 
2669 O OD2 . ASP B 152 ? 1.3794 1.9187 0.8520 0.1140  -0.1054 0.2441  367 ASP B OD2 
2670 N N   . GLY B 153 ? 0.9949 1.6895 0.6104 0.1823  -0.1546 0.0639  368 GLY B N   
2671 C CA  . GLY B 153 ? 0.9901 1.6911 0.6309 0.2006  -0.1795 0.0436  368 GLY B CA  
2672 C C   . GLY B 153 ? 1.0173 1.6676 0.7143 0.1971  -0.1795 0.0381  368 GLY B C   
2673 O O   . GLY B 153 ? 1.0819 1.7034 0.7816 0.2102  -0.1927 0.0602  368 GLY B O   
2674 N N   . ARG B 154 ? 0.9845 1.6223 0.7234 0.1821  -0.1645 0.0094  369 ARG B N   
2675 C CA  . ARG B 154 ? 0.9459 1.5296 0.7292 0.1747  -0.1587 0.0125  369 ARG B CA  
2676 C C   . ARG B 154 ? 0.9246 1.4971 0.7363 0.1596  -0.1398 -0.0127 369 ARG B C   
2677 O O   . ARG B 154 ? 0.9210 1.5092 0.7121 0.1534  -0.1248 -0.0093 369 ARG B O   
2678 C CB  . ARG B 154 ? 0.9775 1.5100 0.7391 0.1732  -0.1541 0.0619  369 ARG B CB  
2679 C CG  . ARG B 154 ? 0.9393 1.4154 0.7399 0.1676  -0.1492 0.0676  369 ARG B CG  
2680 C CD  . ARG B 154 ? 0.9947 1.4350 0.7807 0.1850  -0.1637 0.0982  369 ARG B CD  
2681 N NE  . ARG B 154 ? 1.0057 1.4255 0.8393 0.1910  -0.1688 0.0832  369 ARG B NE  
2682 C CZ  . ARG B 154 ? 0.9880 1.4003 0.8232 0.2146  -0.1856 0.0923  369 ARG B CZ  
2683 N NH1 . ARG B 154 ? 1.0382 1.4546 0.8280 0.2376  -0.2014 0.1178  369 ARG B NH1 
2684 N NH2 . ARG B 154 ? 0.9419 1.3452 0.8233 0.2174  -0.1867 0.0754  369 ARG B NH2 
2685 N N   . PHE B 155 ? 0.8956 1.4439 0.7521 0.1549  -0.1401 -0.0376 370 PHE B N   
2686 C CA  . PHE B 155 ? 0.8824 1.4121 0.7629 0.1455  -0.1253 -0.0627 370 PHE B CA  
2687 C C   . PHE B 155 ? 0.8702 1.3481 0.7731 0.1366  -0.1134 -0.0404 370 PHE B C   
2688 O O   . PHE B 155 ? 0.8487 1.2982 0.7686 0.1361  -0.1195 -0.0262 370 PHE B O   
2689 C CB  . PHE B 155 ? 0.8855 1.4166 0.7930 0.1427  -0.1336 -0.1065 370 PHE B CB  
2690 C CG  . PHE B 155 ? 0.8979 1.4809 0.7843 0.1486  -0.1468 -0.1345 370 PHE B CG  
2691 C CD1 . PHE B 155 ? 0.9038 1.5168 0.7598 0.1544  -0.1407 -0.1494 370 PHE B CD1 
2692 C CD2 . PHE B 155 ? 0.8871 1.4951 0.7862 0.1483  -0.1656 -0.1500 370 PHE B CD2 
2693 C CE1 . PHE B 155 ? 0.9010 1.5626 0.7347 0.1597  -0.1536 -0.1788 370 PHE B CE1 
2694 C CE2 . PHE B 155 ? 0.8976 1.5581 0.7776 0.1520  -0.1796 -0.1785 370 PHE B CE2 
2695 C CZ  . PHE B 155 ? 0.8798 1.5639 0.7250 0.1575  -0.1737 -0.1934 370 PHE B CZ  
2696 N N   . VAL B 156 ? 0.8249 1.2961 0.7278 0.1313  -0.0970 -0.0394 371 VAL B N   
2697 C CA  . VAL B 156 ? 0.8142 1.2439 0.7360 0.1219  -0.0861 -0.0203 371 VAL B CA  
2698 C C   . VAL B 156 ? 0.8045 1.2152 0.7519 0.1226  -0.0783 -0.0481 371 VAL B C   
2699 O O   . VAL B 156 ? 0.7790 1.2125 0.7193 0.1309  -0.0746 -0.0741 371 VAL B O   
2700 C CB  . VAL B 156 ? 0.8150 1.2568 0.7124 0.1128  -0.0741 0.0111  371 VAL B CB  
2701 C CG1 . VAL B 156 ? 0.8528 1.3049 0.7133 0.1129  -0.0819 0.0396  371 VAL B CG1 
2702 C CG2 . VAL B 156 ? 0.8041 1.2921 0.6925 0.1164  -0.0628 -0.0073 371 VAL B CG2 
2703 N N   . TYR B 157 ? 0.7690 1.1351 0.7418 0.1163  -0.0759 -0.0420 372 TYR B N   
2704 C CA  . TYR B 157 ? 0.7609 1.0973 0.7532 0.1177  -0.0697 -0.0628 372 TYR B CA  
2705 C C   . TYR B 157 ? 0.7358 1.0572 0.7349 0.1130  -0.0591 -0.0413 372 TYR B C   
2706 O O   . TYR B 157 ? 0.7195 1.0127 0.7285 0.1036  -0.0595 -0.0208 372 TYR B O   
2707 C CB  . TYR B 157 ? 0.7597 1.0608 0.7736 0.1115  -0.0764 -0.0769 372 TYR B CB  
2708 C CG  . TYR B 157 ? 0.7905 1.1168 0.8006 0.1116  -0.0886 -0.0982 372 TYR B CG  
2709 C CD1 . TYR B 157 ? 0.8035 1.1622 0.8052 0.1141  -0.0991 -0.0832 372 TYR B CD1 
2710 C CD2 . TYR B 157 ? 0.8151 1.1324 0.8259 0.1099  -0.0908 -0.1340 372 TYR B CD2 
2711 C CE1 . TYR B 157 ? 0.8198 1.2120 0.8186 0.1155  -0.1123 -0.1040 372 TYR B CE1 
2712 C CE2 . TYR B 157 ? 0.8215 1.1674 0.8291 0.1060  -0.1029 -0.1568 372 TYR B CE2 
2713 C CZ  . TYR B 157 ? 0.8333 1.2230 0.8369 0.1093  -0.1141 -0.1422 372 TYR B CZ  
2714 O OH  . TYR B 157 ? 0.8532 1.2815 0.8543 0.1068  -0.1282 -0.1664 372 TYR B OH  
2715 N N   . ARG B 158 ? 0.7145 1.0596 0.7083 0.1206  -0.0503 -0.0478 373 ARG B N   
2716 C CA  . ARG B 158 ? 0.6950 1.0437 0.6954 0.1146  -0.0411 -0.0290 373 ARG B CA  
2717 C C   . ARG B 158 ? 0.6710 0.9945 0.6862 0.1271  -0.0382 -0.0462 373 ARG B C   
2718 O O   . ARG B 158 ? 0.6766 1.0115 0.6865 0.1462  -0.0371 -0.0711 373 ARG B O   
2719 C CB  . ARG B 158 ? 0.6937 1.1035 0.6775 0.1124  -0.0324 -0.0201 373 ARG B CB  
2720 C CG  . ARG B 158 ? 0.7196 1.1422 0.6807 0.0963  -0.0340 0.0066  373 ARG B CG  
2721 C CD  . ARG B 158 ? 0.7310 1.2047 0.6764 0.0820  -0.0217 0.0249  373 ARG B CD  
2722 N NE  . ARG B 158 ? 0.7774 1.2578 0.6901 0.0699  -0.0240 0.0486  373 ARG B NE  
2723 C CZ  . ARG B 158 ? 0.7966 1.3055 0.6884 0.0819  -0.0288 0.0377  373 ARG B CZ  
2724 N NH1 . ARG B 158 ? 0.7868 1.3153 0.6879 0.1035  -0.0316 0.0016  373 ARG B NH1 
2725 N NH2 . ARG B 158 ? 0.8239 1.3372 0.6803 0.0725  -0.0318 0.0631  373 ARG B NH2 
2726 N N   . LEU B 159 ? 0.6891 0.9742 0.7186 0.1189  -0.0379 -0.0336 374 LEU B N   
2727 C CA  . LEU B 159 ? 0.6384 0.8980 0.6771 0.1306  -0.0356 -0.0429 374 LEU B CA  
2728 C C   . LEU B 159 ? 0.6725 0.9509 0.7188 0.1207  -0.0306 -0.0215 374 LEU B C   
2729 O O   . LEU B 159 ? 0.6423 0.8859 0.6967 0.1090  -0.0315 -0.0084 374 LEU B O   
2730 C CB  . LEU B 159 ? 0.6669 0.8630 0.7126 0.1266  -0.0399 -0.0490 374 LEU B CB  
2731 C CG  . LEU B 159 ? 0.7117 0.8850 0.7534 0.1255  -0.0454 -0.0700 374 LEU B CG  
2732 C CD1 . LEU B 159 ? 0.6893 0.8764 0.7360 0.1101  -0.0506 -0.0597 374 LEU B CD1 
2733 C CD2 . LEU B 159 ? 0.7440 0.8549 0.7883 0.1232  -0.0452 -0.0801 374 LEU B CD2 
2734 N N   . LEU B 160 ? 0.5616 0.9000 0.6048 0.1222  -0.0247 -0.0189 375 LEU B N   
2735 C CA  . LEU B 160 ? 0.6041 0.9699 0.6533 0.1030  -0.0197 0.0018  375 LEU B CA  
2736 C C   . LEU B 160 ? 0.6123 1.0000 0.6740 0.1192  -0.0184 -0.0072 375 LEU B C   
2737 O O   . LEU B 160 ? 0.5610 0.9702 0.6221 0.1485  -0.0185 -0.0282 375 LEU B O   
2738 C CB  . LEU B 160 ? 0.6084 1.0346 0.6456 0.0867  -0.0125 0.0134  375 LEU B CB  
2739 C CG  . LEU B 160 ? 0.6306 1.0388 0.6482 0.0759  -0.0156 0.0242  375 LEU B CG  
2740 C CD1 . LEU B 160 ? 0.6480 1.1142 0.6462 0.0607  -0.0074 0.0369  375 LEU B CD1 
2741 C CD2 . LEU B 160 ? 0.6556 1.0044 0.6721 0.0582  -0.0208 0.0445  375 LEU B CD2 
2742 N N   . ARG B 161 ? 0.5960 0.9784 0.6666 0.1026  -0.0182 0.0075  376 ARG B N   
2743 C CA  . ARG B 161 ? 0.5985 1.0150 0.6813 0.1158  -0.0186 0.0017  376 ARG B CA  
2744 C C   . ARG B 161 ? 0.5714 0.9492 0.6521 0.1527  -0.0249 -0.0160 376 ARG B C   
2745 O O   . ARG B 161 ? 0.5333 0.9500 0.6181 0.1804  -0.0262 -0.0282 376 ARG B O   
2746 C CB  . ARG B 161 ? 0.5670 1.0791 0.6561 0.1169  -0.0115 -0.0032 376 ARG B CB  
2747 C CG  . ARG B 161 ? 0.5880 1.1327 0.6709 0.0762  -0.0034 0.0163  376 ARG B CG  
2748 C CD  . ARG B 161 ? 0.5646 1.2137 0.6540 0.0715  0.0065  0.0116  376 ARG B CD  
2749 N NE  . ARG B 161 ? 0.5664 1.2732 0.6777 0.0811  0.0053  0.0030  376 ARG B NE  
2750 C CZ  . ARG B 161 ? 0.5698 1.2887 0.6906 0.0496  0.0050  0.0157  376 ARG B CZ  
2751 N NH1 . ARG B 161 ? 0.5692 1.2391 0.6770 0.0069  0.0068  0.0377  376 ARG B NH1 
2752 N NH2 . ARG B 161 ? 0.5224 1.3032 0.6641 0.0631  0.0017  0.0048  376 ARG B NH2 
2753 N N   . SER B 162 ? 0.5975 0.8983 0.6701 0.1532  -0.0287 -0.0169 377 SER B N   
2754 C CA  . SER B 162 ? 0.6241 0.8749 0.6884 0.1807  -0.0337 -0.0285 377 SER B CA  
2755 C C   . SER B 162 ? 0.6195 0.8750 0.6889 0.1829  -0.0367 -0.0184 377 SER B C   
2756 O O   . SER B 162 ? 0.6271 0.8741 0.7027 0.1552  -0.0359 -0.0024 377 SER B O   
2757 C CB  . SER B 162 ? 0.6598 0.8306 0.7152 0.1717  -0.0353 -0.0292 377 SER B CB  
2758 O OG  . SER B 162 ? 0.6787 0.8497 0.7345 0.1560  -0.0340 -0.0319 377 SER B OG  
2759 N N   . PRO B 163 ? 0.6019 0.8647 0.6654 0.2174  -0.0415 -0.0278 378 PRO B N   
2760 C CA  . PRO B 163 ? 0.6458 0.9047 0.7092 0.2222  -0.0469 -0.0180 378 PRO B CA  
2761 C C   . PRO B 163 ? 0.6770 0.8532 0.7284 0.2053  -0.0473 -0.0064 378 PRO B C   
2762 O O   . PRO B 163 ? 0.7001 0.8079 0.7352 0.2113  -0.0467 -0.0112 378 PRO B O   
2763 C CB  . PRO B 163 ? 0.6307 0.8967 0.6821 0.2718  -0.0537 -0.0319 378 PRO B CB  
2764 C CG  . PRO B 163 ? 0.5876 0.9022 0.6434 0.2883  -0.0497 -0.0504 378 PRO B CG  
2765 C CD  . PRO B 163 ? 0.5975 0.8771 0.6520 0.2570  -0.0432 -0.0489 378 PRO B CD  
2766 N N   . MET B 164 ? 0.6274 0.8133 0.6864 0.1812  -0.0474 0.0073  379 MET B N   
2767 C CA  . MET B 164 ? 0.7463 0.8677 0.7932 0.1693  -0.0474 0.0173  379 MET B CA  
2768 C C   . MET B 164 ? 0.7130 0.7898 0.7357 0.2006  -0.0529 0.0164  379 MET B C   
2769 O O   . MET B 164 ? 0.6765 0.7890 0.6955 0.2299  -0.0603 0.0131  379 MET B O   
2770 C CB  . MET B 164 ? 0.6743 0.8246 0.7308 0.1436  -0.0480 0.0280  379 MET B CB  
2771 C CG  . MET B 164 ? 0.7352 0.8360 0.7885 0.1165  -0.0433 0.0362  379 MET B CG  
2772 S SD  . MET B 164 ? 0.5883 0.7118 0.6436 0.0931  -0.0461 0.0440  379 MET B SD  
2773 C CE  . MET B 164 ? 0.6982 0.8259 0.7649 0.0611  -0.0404 0.0476  379 MET B CE  
2774 N N   . CYS B 165 ? 0.7714 0.7711 0.7753 0.1953  -0.0493 0.0192  380 CYS B N   
2775 C CA  . CYS B 165 ? 0.8310 0.7750 0.8027 0.2236  -0.0539 0.0212  380 CYS B CA  
2776 C C   . CYS B 165 ? 0.8154 0.7767 0.7793 0.2291  -0.0599 0.0338  380 CYS B C   
2777 O O   . CYS B 165 ? 0.8064 0.7831 0.7813 0.2007  -0.0568 0.0416  380 CYS B O   
2778 C CB  . CYS B 165 ? 0.8882 0.7455 0.8380 0.2086  -0.0470 0.0236  380 CYS B CB  
2779 S SG  . CYS B 165 ? 0.9867 0.8376 0.9526 0.1624  -0.0367 0.0325  380 CYS B SG  
2780 N N   . GLU B 166 ? 0.8579 0.8171 0.8003 0.2684  -0.0698 0.0344  381 GLU B N   
2781 C CA  . GLU B 166 ? 0.8814 0.8767 0.8180 0.2794  -0.0790 0.0437  381 GLU B CA  
2782 C C   . GLU B 166 ? 0.8897 0.8379 0.8075 0.2543  -0.0748 0.0589  381 GLU B C   
2783 O O   . GLU B 166 ? 0.8846 0.8676 0.7990 0.2554  -0.0818 0.0654  381 GLU B O   
2784 C CB  . GLU B 166 ? 0.9267 0.9148 0.8364 0.3339  -0.0916 0.0421  381 GLU B CB  
2785 C CG  . GLU B 166 ? 0.9803 1.0337 0.8895 0.3572  -0.1054 0.0464  381 GLU B CG  
2786 C CD  . GLU B 166 ? 1.1120 1.1264 0.9800 0.4163  -0.1187 0.0496  381 GLU B CD  
2787 O OE1 . GLU B 166 ? 1.2305 1.1422 1.0616 0.4274  -0.1149 0.0537  381 GLU B OE1 
2788 O OE2 . GLU B 166 ? 1.1574 1.2413 1.0277 0.4521  -0.1335 0.0475  381 GLU B OE2 
2789 N N   . TYR B 167 ? 0.8910 0.7691 0.7973 0.2307  -0.0633 0.0628  382 TYR B N   
2790 C CA  . TYR B 167 ? 0.9060 0.7495 0.7967 0.2056  -0.0567 0.0752  382 TYR B CA  
2791 C C   . TYR B 167 ? 0.9208 0.8133 0.8439 0.1718  -0.0518 0.0717  382 TYR B C   
2792 O O   . TYR B 167 ? 0.8847 0.7891 0.8007 0.1611  -0.0528 0.0776  382 TYR B O   
2793 C CB  . TYR B 167 ? 0.9443 0.7061 0.8139 0.1892  -0.0446 0.0788  382 TYR B CB  
2794 C CG  . TYR B 167 ? 0.9622 0.7001 0.8209 0.1593  -0.0341 0.0889  382 TYR B CG  
2795 C CD1 . TYR B 167 ? 0.9322 0.6994 0.8221 0.1277  -0.0251 0.0827  382 TYR B CD1 
2796 C CD2 . TYR B 167 ? 1.0173 0.7031 0.8309 0.1656  -0.0330 0.1048  382 TYR B CD2 
2797 C CE1 . TYR B 167 ? 0.9552 0.7080 0.8357 0.1045  -0.0148 0.0889  382 TYR B CE1 
2798 C CE2 . TYR B 167 ? 1.0311 0.7030 0.8333 0.1380  -0.0215 0.1131  382 TYR B CE2 
2799 C CZ  . TYR B 167 ? 1.0044 0.7133 0.8423 0.1084  -0.0122 0.1034  382 TYR B CZ  
2800 O OH  . TYR B 167 ? 1.0412 0.7418 0.8680 0.0851  0.0000  0.1086  382 TYR B OH  
2801 N N   . LEU B 168 ? 0.8491 0.7639 0.8027 0.1553  -0.0468 0.0620  383 LEU B N   
2802 C CA  . LEU B 168 ? 0.8619 0.8150 0.8405 0.1274  -0.0438 0.0597  383 LEU B CA  
2803 C C   . LEU B 168 ? 0.8491 0.8652 0.8362 0.1303  -0.0535 0.0588  383 LEU B C   
2804 O O   . LEU B 168 ? 0.8164 0.8456 0.8051 0.1099  -0.0536 0.0598  383 LEU B O   
2805 C CB  . LEU B 168 ? 0.8347 0.7997 0.8381 0.1146  -0.0389 0.0521  383 LEU B CB  
2806 C CG  . LEU B 168 ? 0.8535 0.7731 0.8574 0.0991  -0.0291 0.0506  383 LEU B CG  
2807 C CD1 . LEU B 168 ? 0.8454 0.7862 0.8726 0.0877  -0.0271 0.0441  383 LEU B CD1 
2808 C CD2 . LEU B 168 ? 0.8848 0.7830 0.8813 0.0815  -0.0226 0.0559  383 LEU B CD2 
2809 N N   . VAL B 169 ? 0.7993 0.8579 0.7911 0.1553  -0.0620 0.0545  384 VAL B N   
2810 C CA  . VAL B 169 ? 0.8282 0.9625 0.8341 0.1529  -0.0706 0.0511  384 VAL B CA  
2811 C C   . VAL B 169 ? 0.7803 0.9144 0.7656 0.1573  -0.0782 0.0566  384 VAL B C   
2812 O O   . VAL B 169 ? 0.7538 0.9265 0.7472 0.1343  -0.0814 0.0538  384 VAL B O   
2813 C CB  . VAL B 169 ? 0.7892 0.9827 0.8072 0.1823  -0.0774 0.0431  384 VAL B CB  
2814 C CG1 . VAL B 169 ? 0.7256 1.0111 0.7628 0.1739  -0.0853 0.0379  384 VAL B CG1 
2815 C CG2 . VAL B 169 ? 0.7527 0.9471 0.7873 0.1758  -0.0690 0.0368  384 VAL B CG2 
2816 N N   . ASN B 170 ? 0.8311 0.9172 0.7848 0.1851  -0.0813 0.0647  385 ASN B N   
2817 C CA  . ASN B 170 ? 0.7956 0.8792 0.7230 0.1907  -0.0887 0.0720  385 ASN B CA  
2818 C C   . ASN B 170 ? 0.8398 0.8870 0.7605 0.1555  -0.0784 0.0747  385 ASN B C   
2819 O O   . ASN B 170 ? 0.8277 0.9018 0.7430 0.1422  -0.0833 0.0727  385 ASN B O   
2820 C CB  . ASN B 170 ? 0.8500 0.8799 0.7373 0.2295  -0.0938 0.0834  385 ASN B CB  
2821 C CG  . ASN B 170 ? 0.9328 1.0010 0.8228 0.2737  -0.1065 0.0783  385 ASN B CG  
2822 O OD1 . ASN B 170 ? 0.9936 1.0040 0.8566 0.3053  -0.1077 0.0833  385 ASN B OD1 
2823 N ND2 . ASN B 170 ? 0.9250 1.0915 0.8473 0.2752  -0.1154 0.0667  385 ASN B ND2 
2824 N N   . PHE B 171 ? 0.8142 0.8048 0.7352 0.1408  -0.0644 0.0767  386 PHE B N   
2825 C CA  . PHE B 171 ? 0.8695 0.8339 0.7861 0.1125  -0.0542 0.0768  386 PHE B CA  
2826 C C   . PHE B 171 ? 0.8936 0.9014 0.8328 0.0875  -0.0564 0.0663  386 PHE B C   
2827 O O   . PHE B 171 ? 0.8455 0.8511 0.7730 0.0724  -0.0556 0.0634  386 PHE B O   
2828 C CB  . PHE B 171 ? 0.8665 0.7820 0.7888 0.1008  -0.0398 0.0772  386 PHE B CB  
2829 C CG  . PHE B 171 ? 0.8753 0.7758 0.7996 0.0757  -0.0289 0.0738  386 PHE B CG  
2830 C CD1 . PHE B 171 ? 0.8741 0.7509 0.7689 0.0722  -0.0232 0.0796  386 PHE B CD1 
2831 C CD2 . PHE B 171 ? 0.8151 0.7249 0.7669 0.0588  -0.0241 0.0650  386 PHE B CD2 
2832 C CE1 . PHE B 171 ? 0.8410 0.7106 0.7382 0.0529  -0.0122 0.0733  386 PHE B CE1 
2833 C CE2 . PHE B 171 ? 0.8393 0.7360 0.7921 0.0429  -0.0150 0.0598  386 PHE B CE2 
2834 C CZ  . PHE B 171 ? 0.8644 0.7440 0.7917 0.0402  -0.0085 0.0623  386 PHE B CZ  
2835 N N   . LEU B 172 ? 0.7972 0.8415 0.7644 0.0817  -0.0589 0.0603  387 LEU B N   
2836 C CA  . LEU B 172 ? 0.8305 0.9068 0.8140 0.0537  -0.0605 0.0523  387 LEU B CA  
2837 C C   . LEU B 172 ? 0.7710 0.8999 0.7493 0.0505  -0.0727 0.0474  387 LEU B C   
2838 O O   . LEU B 172 ? 0.7631 0.8958 0.7378 0.0248  -0.0738 0.0402  387 LEU B O   
2839 C CB  . LEU B 172 ? 0.8273 0.9303 0.8366 0.0469  -0.0590 0.0502  387 LEU B CB  
2840 C CG  . LEU B 172 ? 0.7788 0.8414 0.7967 0.0402  -0.0488 0.0519  387 LEU B CG  
2841 C CD1 . LEU B 172 ? 0.7726 0.8713 0.8095 0.0421  -0.0492 0.0512  387 LEU B CD1 
2842 C CD2 . LEU B 172 ? 0.7854 0.8196 0.8009 0.0146  -0.0442 0.0494  387 LEU B CD2 
2843 N N   . HIS B 173 ? 0.7988 0.9719 0.7768 0.0767  -0.0831 0.0490  388 HIS B N   
2844 C CA  . HIS B 173 ? 0.7962 1.0303 0.7706 0.0750  -0.0967 0.0428  388 HIS B CA  
2845 C C   . HIS B 173 ? 0.8399 1.0416 0.7829 0.0718  -0.0982 0.0441  388 HIS B C   
2846 O O   . HIS B 173 ? 0.8100 1.0391 0.7499 0.0481  -0.1039 0.0338  388 HIS B O   
2847 C CB  . HIS B 173 ? 0.7657 1.0535 0.7424 0.1139  -0.1090 0.0444  388 HIS B CB  
2848 C CG  . HIS B 173 ? 0.7800 1.1548 0.7906 0.1058  -0.1136 0.0343  388 HIS B CG  
2849 N ND1 . HIS B 173 ? 0.7578 1.1406 0.7896 0.1103  -0.1060 0.0339  388 HIS B ND1 
2850 C CD2 . HIS B 173 ? 0.7775 1.2418 0.8042 0.0914  -0.1243 0.0234  388 HIS B CD2 
2851 C CE1 . HIS B 173 ? 0.7591 1.2326 0.8179 0.0988  -0.1102 0.0244  388 HIS B CE1 
2852 N NE2 . HIS B 173 ? 0.7951 1.3214 0.8533 0.0858  -0.1213 0.0176  388 HIS B NE2 
2853 N N   . LYS B 174 ? 0.8159 0.9590 0.7324 0.0930  -0.0926 0.0558  389 LYS B N   
2854 C CA  . LYS B 174 ? 0.8959 1.0090 0.7792 0.0885  -0.0911 0.0580  389 LYS B CA  
2855 C C   . LYS B 174 ? 0.8806 0.9694 0.7695 0.0536  -0.0807 0.0471  389 LYS B C   
2856 O O   . LYS B 174 ? 0.8929 0.9973 0.7690 0.0373  -0.0855 0.0365  389 LYS B O   
2857 C CB  . LYS B 174 ? 0.8545 0.9047 0.7068 0.1107  -0.0831 0.0745  389 LYS B CB  
2858 C CG  . LYS B 174 ? 0.8449 0.9042 0.6744 0.1498  -0.0960 0.0864  389 LYS B CG  
2859 C CD  . LYS B 174 ? 0.8815 0.8675 0.6889 0.1661  -0.0860 0.1016  389 LYS B CD  
2860 C CE  . LYS B 174 ? 0.8941 0.8749 0.6721 0.2095  -0.0998 0.1140  389 LYS B CE  
2861 N NZ  . LYS B 174 ? 0.9692 0.8607 0.7139 0.2177  -0.0884 0.1300  389 LYS B NZ  
2862 N N   . LEU B 175 ? 0.8759 0.9262 0.7818 0.0440  -0.0675 0.0477  390 LEU B N   
2863 C CA  . LEU B 175 ? 0.8833 0.9046 0.7911 0.0191  -0.0583 0.0375  390 LEU B CA  
2864 C C   . LEU B 175 ? 0.8764 0.9289 0.7908 -0.0066 -0.0670 0.0233  390 LEU B C   
2865 O O   . LEU B 175 ? 0.8892 0.9226 0.7882 -0.0232 -0.0653 0.0115  390 LEU B O   
2866 C CB  . LEU B 175 ? 0.8546 0.8437 0.7835 0.0169  -0.0468 0.0403  390 LEU B CB  
2867 C CG  . LEU B 175 ? 0.8679 0.8174 0.7950 0.0048  -0.0353 0.0328  390 LEU B CG  
2868 C CD1 . LEU B 175 ? 0.8713 0.7998 0.7719 0.0110  -0.0268 0.0331  390 LEU B CD1 
2869 C CD2 . LEU B 175 ? 0.8357 0.7658 0.7858 0.0070  -0.0274 0.0362  390 LEU B CD2 
2870 N N   . ARG B 176 ? 0.8436 0.9466 0.7779 -0.0112 -0.0763 0.0226  391 ARG B N   
2871 C CA  . ARG B 176 ? 0.8305 0.9645 0.7726 -0.0438 -0.0830 0.0098  391 ARG B CA  
2872 C C   . ARG B 176 ? 0.8321 0.9947 0.7536 -0.0533 -0.0940 -0.0025 391 ARG B C   
2873 O O   . ARG B 176 ? 0.8136 0.9833 0.7329 -0.0870 -0.0979 -0.0172 391 ARG B O   
2874 C CB  . ARG B 176 ? 0.8117 1.0079 0.7815 -0.0460 -0.0886 0.0125  391 ARG B CB  
2875 C CG  . ARG B 176 ? 0.8113 1.0634 0.7901 -0.0810 -0.0972 0.0001  391 ARG B CG  
2876 C CD  . ARG B 176 ? 0.8267 1.1391 0.8354 -0.0825 -0.0973 0.0046  391 ARG B CD  
2877 N NE  . ARG B 176 ? 0.8568 1.1846 0.8746 -0.1295 -0.0949 -0.0014 391 ARG B NE  
2878 C CZ  . ARG B 176 ? 0.8518 1.2558 0.8939 -0.1440 -0.0962 -0.0022 391 ARG B CZ  
2879 N NH1 . ARG B 176 ? 0.8232 1.2984 0.8849 -0.1098 -0.1010 -0.0001 391 ARG B NH1 
2880 N NH2 . ARG B 176 ? 0.8458 1.2524 0.8897 -0.1933 -0.0916 -0.0052 391 ARG B NH2 
2881 N N   . GLN B 177 ? 0.8489 1.0259 0.7513 -0.0258 -0.0997 0.0031  392 GLN B N   
2882 C CA  . GLN B 177 ? 0.8877 1.1054 0.7695 -0.0314 -0.1131 -0.0082 392 GLN B CA  
2883 C C   . GLN B 177 ? 0.9220 1.0911 0.7693 -0.0365 -0.1072 -0.0158 392 GLN B C   
2884 O O   . GLN B 177 ? 0.9204 1.1161 0.7493 -0.0512 -0.1174 -0.0315 392 GLN B O   
2885 C CB  . GLN B 177 ? 0.9197 1.1884 0.7944 0.0052  -0.1262 0.0028  392 GLN B CB  
2886 C CG  . GLN B 177 ? 0.9174 1.2609 0.8262 0.0092  -0.1360 0.0019  392 GLN B CG  
2887 C CD  . GLN B 177 ? 0.9732 1.3259 0.8809 0.0572  -0.1398 0.0187  392 GLN B CD  
2888 O OE1 . GLN B 177 ? 1.0314 1.3639 0.9059 0.0880  -0.1448 0.0296  392 GLN B OE1 
2889 N NE2 . GLN B 177 ? 0.9134 1.2890 0.8521 0.0644  -0.1368 0.0213  392 GLN B NE2 
2890 N N   . LEU B 178 ? 0.9070 1.0126 0.7459 -0.0254 -0.0909 -0.0073 393 LEU B N   
2891 C CA  . LEU B 178 ? 0.9314 0.9934 0.7421 -0.0301 -0.0811 -0.0165 393 LEU B CA  
2892 C C   . LEU B 178 ? 0.9475 1.0093 0.7510 -0.0616 -0.0867 -0.0417 393 LEU B C   
2893 O O   . LEU B 178 ? 0.9289 0.9864 0.7537 -0.0846 -0.0884 -0.0486 393 LEU B O   
2894 C CB  . LEU B 178 ? 0.9171 0.9227 0.7368 -0.0240 -0.0621 -0.0099 393 LEU B CB  
2895 C CG  . LEU B 178 ? 0.9259 0.9138 0.7317 -0.0001 -0.0517 0.0087  393 LEU B CG  
2896 C CD1 . LEU B 178 ? 0.9248 0.9434 0.7294 0.0197  -0.0633 0.0255  393 LEU B CD1 
2897 C CD2 . LEU B 178 ? 0.8958 0.8456 0.7221 0.0023  -0.0356 0.0142  393 LEU B CD2 
2898 N N   . PRO B 179 ? 0.9476 1.0096 0.7170 -0.0647 -0.0894 -0.0560 394 PRO B N   
2899 C CA  . PRO B 179 ? 0.9582 1.0188 0.7151 -0.0964 -0.0972 -0.0839 394 PRO B CA  
2900 C C   . PRO B 179 ? 0.9642 0.9545 0.7200 -0.1105 -0.0851 -0.0979 394 PRO B C   
2901 O O   . PRO B 179 ? 0.9982 0.9729 0.7481 -0.1409 -0.0916 -0.1181 394 PRO B O   
2902 C CB  . PRO B 179 ? 0.9561 1.0360 0.6720 -0.0889 -0.1025 -0.0945 394 PRO B CB  
2903 C CG  . PRO B 179 ? 0.9554 1.0525 0.6620 -0.0542 -0.0997 -0.0677 394 PRO B CG  
2904 C CD  . PRO B 179 ? 0.9661 1.0276 0.7019 -0.0416 -0.0852 -0.0477 394 PRO B CD  
2905 N N   . GLU B 180 ? 0.9630 0.9103 0.7223 -0.0895 -0.0684 -0.0887 395 GLU B N   
2906 C CA  . GLU B 180 ? 0.9513 0.8356 0.7037 -0.0923 -0.0577 -0.1040 395 GLU B CA  
2907 C C   . GLU B 180 ? 0.9119 0.7704 0.6940 -0.0778 -0.0466 -0.0865 395 GLU B C   
2908 O O   . GLU B 180 ? 0.9249 0.8046 0.7220 -0.0589 -0.0404 -0.0663 395 GLU B O   
2909 C CB  . GLU B 180 ? 0.9443 0.8141 0.6649 -0.0771 -0.0476 -0.1184 395 GLU B CB  
2910 C CG  . GLU B 180 ? 0.9735 0.8670 0.6588 -0.0896 -0.0582 -0.1387 395 GLU B CG  
2911 C CD  . GLU B 180 ? 1.0291 0.8837 0.6993 -0.1161 -0.0658 -0.1680 395 GLU B CD  
2912 O OE1 . GLU B 180 ? 1.0323 0.8440 0.7210 -0.1254 -0.0643 -0.1658 395 GLU B OE1 
2913 O OE2 . GLU B 180 ? 1.0540 0.9161 0.6904 -0.1281 -0.0733 -0.1927 395 GLU B OE2 
2914 N N   . ARG B 181 ? 0.9113 0.7195 0.6970 -0.0861 -0.0447 -0.0949 396 ARG B N   
2915 C CA  . ARG B 181 ? 0.9364 0.7230 0.7486 -0.0720 -0.0366 -0.0794 396 ARG B CA  
2916 C C   . ARG B 181 ? 0.9364 0.7182 0.7513 -0.0433 -0.0215 -0.0784 396 ARG B C   
2917 O O   . ARG B 181 ? 0.9024 0.6974 0.7424 -0.0297 -0.0148 -0.0611 396 ARG B O   
2918 C CB  . ARG B 181 ? 0.9836 0.7114 0.7902 -0.0854 -0.0397 -0.0873 396 ARG B CB  
2919 C CG  . ARG B 181 ? 1.0057 0.7315 0.8391 -0.0883 -0.0407 -0.0661 396 ARG B CG  
2920 C CD  . ARG B 181 ? 1.0803 0.7328 0.9004 -0.0885 -0.0402 -0.0704 396 ARG B CD  
2921 N NE  . ARG B 181 ? 1.1077 0.7276 0.9173 -0.0575 -0.0319 -0.0840 396 ARG B NE  
2922 C CZ  . ARG B 181 ? 1.1693 0.7263 0.9651 -0.0426 -0.0312 -0.0901 396 ARG B CZ  
2923 N NH1 . ARG B 181 ? 1.2338 0.7433 1.0202 -0.0573 -0.0379 -0.0802 396 ARG B NH1 
2924 N NH2 . ARG B 181 ? 1.2130 0.7552 1.0014 -0.0111 -0.0234 -0.1064 396 ARG B NH2 
2925 N N   . TYR B 182 ? 0.9046 0.6726 0.6937 -0.0356 -0.0153 -0.0983 397 TYR B N   
2926 C CA  . TYR B 182 ? 0.9254 0.7032 0.7183 -0.0120 0.0012  -0.0983 397 TYR B CA  
2927 C C   . TYR B 182 ? 0.8749 0.6970 0.6741 -0.0089 0.0065  -0.0772 397 TYR B C   
2928 O O   . TYR B 182 ? 0.8477 0.6809 0.6607 0.0038  0.0204  -0.0688 397 TYR B O   
2929 C CB  . TYR B 182 ? 0.9633 0.7272 0.7244 -0.0040 0.0080  -0.1255 397 TYR B CB  
2930 C CG  . TYR B 182 ? 0.9602 0.7544 0.6900 -0.0124 0.0064  -0.1313 397 TYR B CG  
2931 C CD1 . TYR B 182 ? 0.9399 0.7748 0.6664 -0.0057 0.0164  -0.1145 397 TYR B CD1 
2932 C CD2 . TYR B 182 ? 0.9880 0.7666 0.6865 -0.0272 -0.0046 -0.1544 397 TYR B CD2 
2933 C CE1 . TYR B 182 ? 1.0097 0.8705 0.7012 -0.0104 0.0142  -0.1172 397 TYR B CE1 
2934 C CE2 . TYR B 182 ? 1.0179 0.8298 0.6850 -0.0329 -0.0075 -0.1609 397 TYR B CE2 
2935 C CZ  . TYR B 182 ? 0.9923 0.8457 0.6552 -0.0224 0.0017  -0.1410 397 TYR B CZ  
2936 O OH  . TYR B 182 ? 0.9813 0.8659 0.6080 -0.0258 -0.0024 -0.1439 397 TYR B OH  
2937 N N   . MET B 183 ? 0.8506 0.6977 0.6382 -0.0201 -0.0048 -0.0688 398 MET B N   
2938 C CA  . MET B 183 ? 0.9103 0.7870 0.6967 -0.0131 -0.0019 -0.0466 398 MET B CA  
2939 C C   . MET B 183 ? 0.8664 0.7448 0.6868 -0.0091 -0.0027 -0.0263 398 MET B C   
2940 O O   . MET B 183 ? 0.8483 0.7283 0.6754 -0.0002 0.0082  -0.0121 398 MET B O   
2941 C CB  . MET B 183 ? 0.8835 0.7893 0.6444 -0.0191 -0.0163 -0.0448 398 MET B CB  
2942 C CG  . MET B 183 ? 0.9316 0.8468 0.6522 -0.0162 -0.0116 -0.0536 398 MET B CG  
2943 S SD  . MET B 183 ? 0.8677 0.8228 0.5549 -0.0231 -0.0330 -0.0583 398 MET B SD  
2944 C CE  . MET B 183 ? 0.9860 0.9338 0.6306 -0.0275 -0.0263 -0.0879 398 MET B CE  
2945 N N   . MET B 184 ? 0.8555 0.7340 0.6948 -0.0181 -0.0147 -0.0255 399 MET B N   
2946 C CA  . MET B 184 ? 0.8686 0.7484 0.7389 -0.0136 -0.0145 -0.0103 399 MET B CA  
2947 C C   . MET B 184 ? 0.8613 0.7206 0.7475 -0.0040 -0.0008 -0.0111 399 MET B C   
2948 O O   . MET B 184 ? 0.8409 0.7059 0.7439 0.0031  0.0049  0.0016  399 MET B O   
2949 C CB  . MET B 184 ? 0.8370 0.7186 0.7216 -0.0284 -0.0264 -0.0124 399 MET B CB  
2950 C CG  . MET B 184 ? 0.8700 0.7814 0.7422 -0.0438 -0.0404 -0.0180 399 MET B CG  
2951 S SD  . MET B 184 ? 0.7907 0.7063 0.6778 -0.0714 -0.0507 -0.0216 399 MET B SD  
2952 C CE  . MET B 184 ? 0.8724 0.8612 0.7598 -0.0790 -0.0660 -0.0207 399 MET B CE  
2953 N N   . ASN B 185 ? 0.8476 0.6849 0.7275 -0.0025 0.0041  -0.0282 400 ASN B N   
2954 C CA  . ASN B 185 ? 0.8744 0.7039 0.7714 0.0108  0.0160  -0.0320 400 ASN B CA  
2955 C C   . ASN B 185 ? 0.8623 0.7133 0.7557 0.0164  0.0317  -0.0293 400 ASN B C   
2956 O O   . ASN B 185 ? 0.8085 0.6708 0.7242 0.0214  0.0408  -0.0239 400 ASN B O   
2957 C CB  . ASN B 185 ? 0.8828 0.6810 0.7702 0.0173  0.0156  -0.0526 400 ASN B CB  
2958 C CG  . ASN B 185 ? 0.9140 0.6815 0.8096 0.0133  0.0043  -0.0497 400 ASN B CG  
2959 O OD1 . ASN B 185 ? 0.8800 0.6591 0.7960 0.0096  0.0003  -0.0333 400 ASN B OD1 
2960 N ND2 . ASN B 185 ? 0.9367 0.6605 0.8120 0.0136  -0.0004 -0.0654 400 ASN B ND2 
2961 N N   . SER B 186 ? 0.8499 0.7091 0.7134 0.0130  0.0356  -0.0328 401 SER B N   
2962 C CA  . SER B 186 ? 0.8883 0.7656 0.7423 0.0129  0.0518  -0.0250 401 SER B CA  
2963 C C   . SER B 186 ? 0.8506 0.7291 0.7154 0.0089  0.0513  -0.0018 401 SER B C   
2964 O O   . SER B 186 ? 0.7751 0.6605 0.6509 0.0058  0.0650  0.0042  401 SER B O   
2965 C CB  . SER B 186 ? 0.8908 0.7752 0.7033 0.0094  0.0538  -0.0275 401 SER B CB  
2966 O OG  . SER B 186 ? 0.8964 0.7760 0.6941 0.0130  0.0534  -0.0528 401 SER B OG  
2967 N N   . VAL B 187 ? 0.8056 0.6792 0.6647 0.0082  0.0358  0.0097  402 VAL B N   
2968 C CA  . VAL B 187 ? 0.9275 0.7962 0.7921 0.0097  0.0334  0.0293  402 VAL B CA  
2969 C C   . VAL B 187 ? 0.8379 0.7046 0.7393 0.0099  0.0365  0.0287  402 VAL B C   
2970 O O   . VAL B 187 ? 0.7625 0.6236 0.6692 0.0067  0.0452  0.0375  402 VAL B O   
2971 C CB  . VAL B 187 ? 0.8869 0.7618 0.7436 0.0147  0.0148  0.0369  402 VAL B CB  
2972 C CG1 . VAL B 187 ? 0.8718 0.7378 0.7330 0.0228  0.0115  0.0542  402 VAL B CG1 
2973 C CG2 . VAL B 187 ? 0.8598 0.7438 0.6795 0.0158  0.0098  0.0367  402 VAL B CG2 
2974 N N   . LEU B 188 ? 0.8442 0.7129 0.7676 0.0119  0.0295  0.0178  403 LEU B N   
2975 C CA  . LEU B 188 ? 0.8474 0.7177 0.8022 0.0144  0.0297  0.0186  403 LEU B CA  
2976 C C   . LEU B 188 ? 0.7935 0.6747 0.7629 0.0146  0.0447  0.0110  403 LEU B C   
2977 O O   . LEU B 188 ? 0.7243 0.6133 0.7170 0.0140  0.0465  0.0131  403 LEU B O   
2978 C CB  . LEU B 188 ? 0.8449 0.7097 0.8120 0.0164  0.0181  0.0126  403 LEU B CB  
2979 C CG  . LEU B 188 ? 0.8108 0.6789 0.7709 0.0110  0.0043  0.0195  403 LEU B CG  
2980 C CD1 . LEU B 188 ? 0.8405 0.6971 0.8027 0.0046  -0.0042 0.0129  403 LEU B CD1 
2981 C CD2 . LEU B 188 ? 0.8044 0.6832 0.7778 0.0146  0.0004  0.0316  403 LEU B CD2 
2982 N N   . GLU B 189 ? 0.8462 0.7356 0.8030 0.0149  0.0558  0.0005  404 GLU B N   
2983 C CA  . GLU B 189 ? 0.8156 0.7304 0.7888 0.0138  0.0720  -0.0080 404 GLU B CA  
2984 C C   . GLU B 189 ? 0.8385 0.7573 0.8180 -0.0009 0.0799  0.0048  404 GLU B C   
2985 O O   . GLU B 189 ? 0.8116 0.7538 0.8189 -0.0046 0.0863  -0.0009 404 GLU B O   
2986 C CB  . GLU B 189 ? 0.8209 0.7492 0.7723 0.0134  0.0857  -0.0184 404 GLU B CB  
2987 C CG  . GLU B 189 ? 0.8606 0.7990 0.8198 0.0313  0.0866  -0.0412 404 GLU B CG  
2988 C CD  . GLU B 189 ? 0.9758 0.9219 0.9044 0.0325  0.0973  -0.0534 404 GLU B CD  
2989 O OE1 . GLU B 189 ? 1.0034 0.9780 0.9243 0.0214  0.1155  -0.0510 404 GLU B OE1 
2990 O OE2 . GLU B 189 ? 0.9535 0.8765 0.8629 0.0420  0.0881  -0.0659 404 GLU B OE2 
2991 N N   . ASN B 190 ? 0.7898 0.6836 0.7417 -0.0085 0.0777  0.0213  405 ASN B N   
2992 C CA  . ASN B 190 ? 0.8816 0.7611 0.8252 -0.0235 0.0857  0.0347  405 ASN B CA  
2993 C C   . ASN B 190 ? 0.8939 0.7507 0.8450 -0.0187 0.0719  0.0434  405 ASN B C   
2994 O O   . ASN B 190 ? 0.9271 0.7536 0.8573 -0.0254 0.0737  0.0566  405 ASN B O   
2995 C CB  . ASN B 190 ? 0.9350 0.7938 0.8329 -0.0308 0.0933  0.0485  405 ASN B CB  
2996 C CG  . ASN B 190 ? 0.9401 0.8266 0.8272 -0.0356 0.1086  0.0382  405 ASN B CG  
2997 O OD1 . ASN B 190 ? 0.8914 0.8123 0.8021 -0.0437 0.1233  0.0253  405 ASN B OD1 
2998 N ND2 . ASN B 190 ? 0.9626 0.8415 0.8144 -0.0290 0.1050  0.0415  405 ASN B ND2 
2999 N N   . PHE B 191 ? 0.8527 0.7205 0.8292 -0.0065 0.0588  0.0363  406 PHE B N   
3000 C CA  . PHE B 191 ? 0.8577 0.7123 0.8403 0.0003  0.0458  0.0427  406 PHE B CA  
3001 C C   . PHE B 191 ? 0.8708 0.7460 0.8884 0.0019  0.0427  0.0326  406 PHE B C   
3002 O O   . PHE B 191 ? 0.8301 0.7216 0.8625 0.0098  0.0379  0.0249  406 PHE B O   
3003 C CB  . PHE B 191 ? 0.8397 0.6925 0.8108 0.0125  0.0313  0.0471  406 PHE B CB  
3004 C CG  . PHE B 191 ? 0.8180 0.6713 0.7994 0.0213  0.0192  0.0507  406 PHE B CG  
3005 C CD1 . PHE B 191 ? 0.8310 0.6656 0.7940 0.0294  0.0150  0.0603  406 PHE B CD1 
3006 C CD2 . PHE B 191 ? 0.8156 0.6870 0.8215 0.0237  0.0123  0.0445  406 PHE B CD2 
3007 C CE1 . PHE B 191 ? 0.8420 0.6838 0.8153 0.0411  0.0046  0.0603  406 PHE B CE1 
3008 C CE2 . PHE B 191 ? 0.8119 0.6912 0.8262 0.0310  0.0029  0.0471  406 PHE B CE2 
3009 C CZ  . PHE B 191 ? 0.8052 0.6735 0.8052 0.0402  -0.0004 0.0533  406 PHE B CZ  
3010 N N   . THR B 192 ? 0.7950 0.6659 0.8219 -0.0052 0.0447  0.0323  407 THR B N   
3011 C CA  . THR B 192 ? 0.8575 0.7533 0.9154 -0.0030 0.0402  0.0223  407 THR B CA  
3012 C C   . THR B 192 ? 0.8782 0.7594 0.9359 -0.0023 0.0330  0.0242  407 THR B C   
3013 O O   . THR B 192 ? 0.8554 0.7033 0.8901 -0.0050 0.0342  0.0314  407 THR B O   
3014 C CB  . THR B 192 ? 0.8802 0.8063 0.9584 -0.0153 0.0522  0.0107  407 THR B CB  
3015 O OG1 . THR B 192 ? 0.9399 0.8494 1.0076 -0.0370 0.0627  0.0128  407 THR B OG1 
3016 C CG2 . THR B 192 ? 0.8941 0.8367 0.9695 -0.0128 0.0613  0.0062  407 THR B CG2 
3017 N N   . ILE B 193 ? 0.8305 0.7344 0.9102 0.0042  0.0248  0.0174  408 ILE B N   
3018 C CA  . ILE B 193 ? 0.8466 0.7445 0.9277 0.0065  0.0179  0.0148  408 ILE B CA  
3019 C C   . ILE B 193 ? 0.7969 0.7250 0.9031 -0.0012 0.0182  0.0014  408 ILE B C   
3020 O O   . ILE B 193 ? 0.7544 0.7152 0.8796 0.0040  0.0168  -0.0032 408 ILE B O   
3021 C CB  . ILE B 193 ? 0.7978 0.7021 0.8767 0.0230  0.0058  0.0204  408 ILE B CB  
3022 C CG1 . ILE B 193 ? 0.8123 0.6975 0.8690 0.0295  0.0044  0.0309  408 ILE B CG1 
3023 C CG2 . ILE B 193 ? 0.8206 0.7280 0.9021 0.0279  -0.0005 0.0143  408 ILE B CG2 
3024 C CD1 . ILE B 193 ? 0.8006 0.7041 0.8583 0.0403  -0.0055 0.0350  408 ILE B CD1 
3025 N N   . LEU B 194 ? 0.8172 0.7334 0.9213 -0.0126 0.0193  -0.0063 409 LEU B N   
3026 C CA  . LEU B 194 ? 0.8111 0.7621 0.9389 -0.0226 0.0179  -0.0220 409 LEU B CA  
3027 C C   . LEU B 194 ? 0.8099 0.7553 0.9334 -0.0154 0.0074  -0.0285 409 LEU B C   
3028 O O   . LEU B 194 ? 0.7937 0.6969 0.8953 -0.0183 0.0082  -0.0292 409 LEU B O   
3029 C CB  . LEU B 194 ? 0.8006 0.7487 0.9305 -0.0520 0.0311  -0.0304 409 LEU B CB  
3030 C CG  . LEU B 194 ? 0.7907 0.7874 0.9492 -0.0661 0.0291  -0.0500 409 LEU B CG  
3031 C CD1 . LEU B 194 ? 0.7544 0.8132 0.9426 -0.0507 0.0253  -0.0538 409 LEU B CD1 
3032 C CD2 . LEU B 194 ? 0.8702 0.8575 1.0261 -0.1040 0.0432  -0.0588 409 LEU B CD2 
3033 N N   . GLN B 195 ? 0.7900 0.7754 0.9303 -0.0034 -0.0027 -0.0332 410 GLN B N   
3034 C CA  . GLN B 195 ? 0.7645 0.7550 0.8998 0.0054  -0.0126 -0.0398 410 GLN B CA  
3035 C C   . GLN B 195 ? 0.7245 0.7501 0.8775 -0.0067 -0.0165 -0.0593 410 GLN B C   
3036 O O   . GLN B 195 ? 0.6837 0.7551 0.8588 -0.0048 -0.0197 -0.0625 410 GLN B O   
3037 C CB  . GLN B 195 ? 0.7245 0.7341 0.8582 0.0264  -0.0214 -0.0278 410 GLN B CB  
3038 C CG  . GLN B 195 ? 0.7655 0.7489 0.8792 0.0364  -0.0213 -0.0177 410 GLN B CG  
3039 C CD  . GLN B 195 ? 0.7604 0.7678 0.8703 0.0499  -0.0287 -0.0092 410 GLN B CD  
3040 O OE1 . GLN B 195 ? 0.7158 0.7465 0.8324 0.0530  -0.0336 -0.0038 410 GLN B OE1 
3041 N NE2 . GLN B 195 ? 0.7606 0.7627 0.8573 0.0586  -0.0294 -0.0073 410 GLN B NE2 
3042 N N   . VAL B 196 ? 0.7710 0.7763 0.9129 -0.0170 -0.0176 -0.0739 411 VAL B N   
3043 C CA  . VAL B 196 ? 0.7483 0.7858 0.9043 -0.0337 -0.0221 -0.0966 411 VAL B CA  
3044 C C   . VAL B 196 ? 0.7781 0.8205 0.9216 -0.0197 -0.0332 -0.1066 411 VAL B C   
3045 O O   . VAL B 196 ? 0.8123 0.8079 0.9308 -0.0146 -0.0319 -0.1093 411 VAL B O   
3046 C CB  . VAL B 196 ? 0.7659 0.7693 0.9161 -0.0679 -0.0115 -0.1097 411 VAL B CB  
3047 C CG1 . VAL B 196 ? 0.7651 0.8118 0.9334 -0.0906 -0.0168 -0.1364 411 VAL B CG1 
3048 C CG2 . VAL B 196 ? 0.7393 0.7397 0.8971 -0.0818 0.0021  -0.0976 411 VAL B CG2 
3049 N N   . VAL B 197 ? 0.7715 0.8715 0.9295 -0.0104 -0.0443 -0.1123 412 VAL B N   
3050 C CA  . VAL B 197 ? 0.7955 0.9116 0.9406 0.0013  -0.0549 -0.1237 412 VAL B CA  
3051 C C   . VAL B 197 ? 0.8219 0.9694 0.9782 -0.0197 -0.0610 -0.1524 412 VAL B C   
3052 O O   . VAL B 197 ? 0.7880 0.9908 0.9699 -0.0257 -0.0659 -0.1572 412 VAL B O   
3053 C CB  . VAL B 197 ? 0.7693 0.9251 0.9138 0.0267  -0.0638 -0.1065 412 VAL B CB  
3054 C CG1 . VAL B 197 ? 0.7904 0.9687 0.9183 0.0368  -0.0732 -0.1186 412 VAL B CG1 
3055 C CG2 . VAL B 197 ? 0.7665 0.8929 0.9001 0.0402  -0.0575 -0.0808 412 VAL B CG2 
3056 N N   . THR B 198 ? 0.8610 0.9754 0.9975 -0.0297 -0.0614 -0.1736 413 THR B N   
3057 C CA  . THR B 198 ? 0.8754 1.0113 1.0189 -0.0565 -0.0667 -0.2047 413 THR B CA  
3058 C C   . THR B 198 ? 0.8903 1.0383 1.0135 -0.0434 -0.0780 -0.2239 413 THR B C   
3059 O O   . THR B 198 ? 0.8932 1.0100 0.9916 -0.0198 -0.0769 -0.2174 413 THR B O   
3060 C CB  . THR B 198 ? 0.9170 0.9876 1.0496 -0.0908 -0.0551 -0.2175 413 THR B CB  
3061 O OG1 . THR B 198 ? 0.9685 0.9758 1.0650 -0.0862 -0.0561 -0.2328 413 THR B OG1 
3062 C CG2 . THR B 198 ? 0.8938 0.9203 1.0243 -0.0903 -0.0412 -0.1908 413 THR B CG2 
3063 N N   . ASN B 199 ? 0.9121 1.1139 1.0469 -0.0583 -0.0890 -0.2492 414 ASN B N   
3064 C CA  . ASN B 199 ? 0.9260 1.1406 1.0391 -0.0522 -0.0999 -0.2749 414 ASN B CA  
3065 C C   . ASN B 199 ? 0.9727 1.1050 1.0575 -0.0706 -0.0931 -0.2991 414 ASN B C   
3066 O O   . ASN B 199 ? 1.0107 1.1225 1.0998 -0.1091 -0.0906 -0.3210 414 ASN B O   
3067 C CB  . ASN B 199 ? 0.9512 1.2498 1.0850 -0.0653 -0.1149 -0.2967 414 ASN B CB  
3068 C CG  . ASN B 199 ? 0.9722 1.2961 1.0814 -0.0549 -0.1280 -0.3215 414 ASN B CG  
3069 O OD1 . ASN B 199 ? 0.9958 1.2630 1.0739 -0.0523 -0.1241 -0.3371 414 ASN B OD1 
3070 N ND2 . ASN B 199 ? 0.9669 1.3770 1.0872 -0.0456 -0.1442 -0.3260 414 ASN B ND2 
3071 N N   . ARG B 200 ? 0.9371 1.0211 0.9906 -0.0434 -0.0900 -0.2959 415 ARG B N   
3072 C CA  . ARG B 200 ? 0.9976 0.9864 1.0194 -0.0521 -0.0828 -0.3128 415 ARG B CA  
3073 C C   . ARG B 200 ? 1.0444 1.0181 1.0512 -0.0817 -0.0897 -0.3560 415 ARG B C   
3074 O O   . ARG B 200 ? 1.1043 0.9929 1.0883 -0.1062 -0.0833 -0.3714 415 ARG B O   
3075 C CB  . ARG B 200 ? 0.9901 0.9439 0.9821 -0.0107 -0.0805 -0.3070 415 ARG B CB  
3076 C CG  . ARG B 200 ? 1.0497 0.9116 1.0015 -0.0123 -0.0786 -0.3354 415 ARG B CG  
3077 C CD  . ARG B 200 ? 1.0937 0.9350 1.0176 0.0342  -0.0779 -0.3364 415 ARG B CD  
3078 N NE  . ARG B 200 ? 1.1093 0.9860 1.0158 0.0496  -0.0865 -0.3682 415 ARG B NE  
3079 C CZ  . ARG B 200 ? 1.1412 0.9913 1.0166 0.0870  -0.0858 -0.3830 415 ARG B CZ  
3080 N NH1 . ARG B 200 ? 1.1519 0.9495 1.0143 0.1151  -0.0786 -0.3665 415 ARG B NH1 
3081 N NH2 . ARG B 200 ? 1.1115 0.9920 0.9675 0.0986  -0.0930 -0.4167 415 ARG B NH2 
3082 N N   . ASP B 201 ? 1.0310 1.0810 1.0453 -0.0807 -0.1032 -0.3764 416 ASP B N   
3083 C CA  . ASP B 201 ? 1.0789 1.1164 1.0760 -0.1094 -0.1112 -0.4220 416 ASP B CA  
3084 C C   . ASP B 201 ? 1.0882 1.1550 1.1146 -0.1618 -0.1125 -0.4361 416 ASP B C   
3085 O O   . ASP B 201 ? 1.1162 1.1420 1.1261 -0.2004 -0.1139 -0.4719 416 ASP B O   
3086 C CB  . ASP B 201 ? 1.0554 1.1642 1.0423 -0.0871 -0.1262 -0.4427 416 ASP B CB  
3087 C CG  . ASP B 201 ? 1.0676 1.1480 1.0202 -0.0410 -0.1232 -0.4395 416 ASP B CG  
3088 O OD1 . ASP B 201 ? 1.0878 1.0761 1.0140 -0.0313 -0.1136 -0.4415 416 ASP B OD1 
3089 O OD2 . ASP B 201 ? 1.0335 1.1855 0.9824 -0.0145 -0.1310 -0.4373 416 ASP B OD2 
3090 N N   . THR B 202 ? 1.0750 1.2124 1.1434 -0.1650 -0.1117 -0.4106 417 THR B N   
3091 C CA  . THR B 202 ? 1.0832 1.2755 1.1869 -0.2104 -0.1133 -0.4249 417 THR B CA  
3092 C C   . THR B 202 ? 1.0884 1.2438 1.2090 -0.2364 -0.0956 -0.4029 417 THR B C   
3093 O O   . THR B 202 ? 1.0735 1.2548 1.2160 -0.2846 -0.0921 -0.4198 417 THR B O   
3094 C CB  . THR B 202 ? 1.0343 1.3540 1.1746 -0.1918 -0.1287 -0.4191 417 THR B CB  
3095 O OG1 . THR B 202 ? 1.0285 1.3603 1.1803 -0.1523 -0.1241 -0.3757 417 THR B OG1 
3096 C CG2 . THR B 202 ? 0.9993 1.3629 1.1194 -0.1716 -0.1469 -0.4426 417 THR B CG2 
3097 N N   . GLN B 203 ? 1.0963 1.1961 1.2059 -0.2083 -0.0841 -0.3675 418 GLN B N   
3098 C CA  . GLN B 203 ? 1.0980 1.1662 1.2193 -0.2240 -0.0674 -0.3416 418 GLN B CA  
3099 C C   . GLN B 203 ? 1.0302 1.1979 1.1989 -0.2143 -0.0689 -0.3224 418 GLN B C   
3100 O O   . GLN B 203 ? 1.0281 1.1823 1.2082 -0.2189 -0.0555 -0.2989 418 GLN B O   
3101 C CB  . GLN B 203 ? 1.1392 1.1519 1.2509 -0.2838 -0.0555 -0.3601 418 GLN B CB  
3102 C CG  . GLN B 203 ? 1.2389 1.1657 1.3052 -0.3043 -0.0588 -0.3932 418 GLN B CG  
3103 C CD  . GLN B 203 ? 1.2795 1.0917 1.2957 -0.2686 -0.0540 -0.3788 418 GLN B CD  
3104 O OE1 . GLN B 203 ? 1.2488 1.0391 1.2640 -0.2391 -0.0460 -0.3434 418 GLN B OE1 
3105 N NE2 . GLN B 203 ? 1.2876 1.0291 1.2616 -0.2691 -0.0598 -0.4083 418 GLN B NE2 
3106 N N   . GLU B 204 ? 0.9990 1.2637 1.1917 -0.1980 -0.0855 -0.3320 419 GLU B N   
3107 C CA  . GLU B 204 ? 0.9469 1.2976 1.1780 -0.1779 -0.0893 -0.3129 419 GLU B CA  
3108 C C   . GLU B 204 ? 0.9527 1.2613 1.1770 -0.1452 -0.0793 -0.2734 419 GLU B C   
3109 O O   . GLU B 204 ? 0.9660 1.2211 1.1605 -0.1175 -0.0792 -0.2586 419 GLU B O   
3110 C CB  . GLU B 204 ? 0.9208 1.3571 1.1607 -0.1469 -0.1110 -0.3189 419 GLU B CB  
3111 C CG  . GLU B 204 ? 1.0053 1.4893 1.2447 -0.1694 -0.1260 -0.3592 419 GLU B CG  
3112 C CD  . GLU B 204 ? 1.0802 1.6192 1.3071 -0.1290 -0.1465 -0.3582 419 GLU B CD  
3113 O OE1 . GLU B 204 ? 1.1517 1.6643 1.3462 -0.1276 -0.1526 -0.3772 419 GLU B OE1 
3114 O OE2 . GLU B 204 ? 1.0214 1.6266 1.2666 -0.0972 -0.1561 -0.3381 419 GLU B OE2 
3115 N N   . LEU B 205 ? 0.8696 1.2094 1.1222 -0.1486 -0.0709 -0.2588 420 LEU B N   
3116 C CA  . LEU B 205 ? 0.8292 1.1540 1.0808 -0.1131 -0.0664 -0.2244 420 LEU B CA  
3117 C C   . LEU B 205 ? 0.7802 1.1656 1.0388 -0.0721 -0.0836 -0.2145 420 LEU B C   
3118 O O   . LEU B 205 ? 0.7396 1.2069 1.0232 -0.0700 -0.0961 -0.2288 420 LEU B O   
3119 C CB  . LEU B 205 ? 0.7748 1.1154 1.0515 -0.1284 -0.0519 -0.2157 420 LEU B CB  
3120 C CG  . LEU B 205 ? 0.7539 1.0698 1.0257 -0.0957 -0.0463 -0.1835 420 LEU B CG  
3121 C CD1 . LEU B 205 ? 0.7836 1.0277 1.0388 -0.1147 -0.0268 -0.1705 420 LEU B CD1 
3122 C CD2 . LEU B 205 ? 0.7273 1.1229 1.0330 -0.0770 -0.0510 -0.1809 420 LEU B CD2 
3123 N N   . LEU B 206 ? 0.7669 1.1136 1.0013 -0.0401 -0.0848 -0.1895 421 LEU B N   
3124 C CA  . LEU B 206 ? 0.7879 1.1772 1.0202 -0.0037 -0.0993 -0.1744 421 LEU B CA  
3125 C C   . LEU B 206 ? 0.7345 1.1101 0.9697 0.0200  -0.0947 -0.1446 421 LEU B C   
3126 O O   . LEU B 206 ? 0.6949 1.1126 0.9368 0.0460  -0.1060 -0.1350 421 LEU B O   
3127 C CB  . LEU B 206 ? 0.7899 1.1558 0.9883 0.0122  -0.1057 -0.1702 421 LEU B CB  
3128 C CG  . LEU B 206 ? 0.8152 1.1883 1.0017 -0.0046 -0.1118 -0.2014 421 LEU B CG  
3129 C CD1 . LEU B 206 ? 0.8379 1.1984 0.9908 0.0178  -0.1166 -0.1946 421 LEU B CD1 
3130 C CD2 . LEU B 206 ? 0.8383 1.2920 1.0473 -0.0134 -0.1265 -0.2252 421 LEU B CD2 
3131 N N   . LEU B 207 ? 0.7450 1.0598 0.9719 0.0129  -0.0794 -0.1309 422 LEU B N   
3132 C CA  . LEU B 207 ? 0.7109 1.0051 0.9353 0.0331  -0.0750 -0.1051 422 LEU B CA  
3133 C C   . LEU B 207 ? 0.6865 0.9313 0.9103 0.0139  -0.0575 -0.1011 422 LEU B C   
3134 O O   . LEU B 207 ? 0.6787 0.8762 0.8845 0.0006  -0.0509 -0.1032 422 LEU B O   
3135 C CB  . LEU B 207 ? 0.7163 0.9825 0.9114 0.0557  -0.0804 -0.0830 422 LEU B CB  
3136 C CG  . LEU B 207 ? 0.6915 0.9460 0.8790 0.0792  -0.0826 -0.0580 422 LEU B CG  
3137 C CD1 . LEU B 207 ? 0.6961 1.0024 0.8996 0.0987  -0.0947 -0.0613 422 LEU B CD1 
3138 C CD2 . LEU B 207 ? 0.7260 0.9580 0.8826 0.0907  -0.0867 -0.0393 422 LEU B CD2 
3139 N N   . CYS B 208 ? 0.6846 0.9408 0.9251 0.0155  -0.0505 -0.0959 423 CYS B N   
3140 C CA  . CYS B 208 ? 0.6682 0.8814 0.9045 -0.0007 -0.0338 -0.0896 423 CYS B CA  
3141 C C   . CYS B 208 ? 0.6715 0.8715 0.9037 0.0218  -0.0318 -0.0705 423 CYS B C   
3142 O O   . CYS B 208 ? 0.6694 0.9098 0.9190 0.0378  -0.0355 -0.0727 423 CYS B O   
3143 C CB  . CYS B 208 ? 0.6771 0.9206 0.9365 -0.0311 -0.0230 -0.1079 423 CYS B CB  
3144 S SG  . CYS B 208 ? 0.6399 0.8322 0.8873 -0.0513 -0.0013 -0.0968 423 CYS B SG  
3145 N N   . THR B 209 ? 0.6671 0.8119 0.8754 0.0245  -0.0267 -0.0541 424 THR B N   
3146 C CA  . THR B 209 ? 0.7069 0.8303 0.9058 0.0413  -0.0253 -0.0376 424 THR B CA  
3147 C C   . THR B 209 ? 0.7280 0.8176 0.9190 0.0270  -0.0107 -0.0336 424 THR B C   
3148 O O   . THR B 209 ? 0.6957 0.7498 0.8706 0.0146  -0.0059 -0.0303 424 THR B O   
3149 C CB  . THR B 209 ? 0.7063 0.8034 0.8823 0.0555  -0.0338 -0.0213 424 THR B CB  
3150 O OG1 . THR B 209 ? 0.6547 0.7832 0.8325 0.0687  -0.0469 -0.0230 424 THR B OG1 
3151 C CG2 . THR B 209 ? 0.7165 0.7868 0.8803 0.0675  -0.0328 -0.0065 424 THR B CG2 
3152 N N   . ALA B 210 ? 0.6878 0.7890 0.8872 0.0321  -0.0045 -0.0343 425 ALA B N   
3153 C CA  . ALA B 210 ? 0.7323 0.8055 0.9201 0.0221  0.0088  -0.0292 425 ALA B CA  
3154 C C   . ALA B 210 ? 0.6750 0.7178 0.8445 0.0398  0.0045  -0.0161 425 ALA B C   
3155 O O   . ALA B 210 ? 0.6661 0.7188 0.8390 0.0599  -0.0029 -0.0158 425 ALA B O   
3156 C CB  . ALA B 210 ? 0.7453 0.8582 0.9533 0.0141  0.0207  -0.0419 425 ALA B CB  
3157 N N   . TYR B 211 ? 0.7284 0.7325 0.8759 0.0327  0.0080  -0.0058 426 TYR B N   
3158 C CA  . TYR B 211 ? 0.7205 0.6977 0.8499 0.0427  0.0035  0.0047  426 TYR B CA  
3159 C C   . TYR B 211 ? 0.7461 0.7089 0.8639 0.0378  0.0137  0.0043  426 TYR B C   
3160 O O   . TYR B 211 ? 0.7573 0.7108 0.8666 0.0242  0.0222  0.0059  426 TYR B O   
3161 C CB  . TYR B 211 ? 0.7116 0.6692 0.8259 0.0401  -0.0028 0.0153  426 TYR B CB  
3162 C CG  . TYR B 211 ? 0.7265 0.6993 0.8464 0.0454  -0.0123 0.0163  426 TYR B CG  
3163 C CD1 . TYR B 211 ? 0.7001 0.6720 0.8136 0.0547  -0.0211 0.0243  426 TYR B CD1 
3164 C CD2 . TYR B 211 ? 0.7210 0.7039 0.8469 0.0399  -0.0122 0.0095  426 TYR B CD2 
3165 C CE1 . TYR B 211 ? 0.7050 0.6933 0.8188 0.0589  -0.0288 0.0268  426 TYR B CE1 
3166 C CE2 . TYR B 211 ? 0.7208 0.7205 0.8487 0.0453  -0.0205 0.0084  426 TYR B CE2 
3167 C CZ  . TYR B 211 ? 0.7114 0.7176 0.8335 0.0551  -0.0285 0.0177  426 TYR B CZ  
3168 O OH  . TYR B 211 ? 0.7247 0.7511 0.8448 0.0597  -0.0359 0.0173  426 TYR B OH  
3169 N N   . VAL B 212 ? 0.7174 0.6728 0.8294 0.0497  0.0123  0.0024  427 VAL B N   
3170 C CA  . VAL B 212 ? 0.7362 0.6760 0.8315 0.0466  0.0202  0.0006  427 VAL B CA  
3171 C C   . VAL B 212 ? 0.7662 0.6733 0.8407 0.0503  0.0110  0.0069  427 VAL B C   
3172 O O   . VAL B 212 ? 0.7742 0.6711 0.8479 0.0569  0.0009  0.0119  427 VAL B O   
3173 C CB  . VAL B 212 ? 0.7148 0.6790 0.8207 0.0554  0.0298  -0.0138 427 VAL B CB  
3174 C CG1 . VAL B 212 ? 0.7252 0.7301 0.8538 0.0436  0.0400  -0.0206 427 VAL B CG1 
3175 C CG2 . VAL B 212 ? 0.7333 0.6978 0.8447 0.0797  0.0210  -0.0201 427 VAL B CG2 
3176 N N   . PHE B 213 ? 0.7398 0.6309 0.7943 0.0432  0.0146  0.0071  428 PHE B N   
3177 C CA  . PHE B 213 ? 0.7909 0.6573 0.8255 0.0375  0.0059  0.0124  428 PHE B CA  
3178 C C   . PHE B 213 ? 0.8237 0.6708 0.8378 0.0382  0.0085  0.0024  428 PHE B C   
3179 O O   . PHE B 213 ? 0.8156 0.6728 0.8265 0.0407  0.0187  -0.0059 428 PHE B O   
3180 C CB  . PHE B 213 ? 0.7669 0.6403 0.7955 0.0267  0.0036  0.0223  428 PHE B CB  
3181 C CG  . PHE B 213 ? 0.8162 0.7042 0.8603 0.0278  0.0005  0.0292  428 PHE B CG  
3182 C CD1 . PHE B 213 ? 0.7728 0.6702 0.8267 0.0280  0.0075  0.0279  428 PHE B CD1 
3183 C CD2 . PHE B 213 ? 0.7866 0.6781 0.8328 0.0263  -0.0085 0.0356  428 PHE B CD2 
3184 C CE1 . PHE B 213 ? 0.8020 0.7084 0.8668 0.0291  0.0040  0.0304  428 PHE B CE1 
3185 C CE2 . PHE B 213 ? 0.7586 0.6663 0.8167 0.0293  -0.0109 0.0391  428 PHE B CE2 
3186 C CZ  . PHE B 213 ? 0.7556 0.6687 0.8226 0.0320  -0.0054 0.0352  428 PHE B CZ  
3187 N N   . GLU B 214 ? 0.8441 0.6621 0.8421 0.0342  -0.0004 0.0022  429 GLU B N   
3188 C CA  . GLU B 214 ? 0.8656 0.6605 0.8380 0.0265  -0.0018 -0.0070 429 GLU B CA  
3189 C C   . GLU B 214 ? 0.8708 0.6570 0.8335 0.0067  -0.0124 0.0015  429 GLU B C   
3190 O O   . GLU B 214 ? 0.8352 0.6331 0.8108 0.0026  -0.0167 0.0138  429 GLU B O   
3191 C CB  . GLU B 214 ? 0.8718 0.6315 0.8308 0.0412  -0.0014 -0.0216 429 GLU B CB  
3192 C CG  . GLU B 214 ? 0.8851 0.6670 0.8562 0.0619  0.0099  -0.0336 429 GLU B CG  
3193 C CD  . GLU B 214 ? 0.9366 0.6848 0.8917 0.0825  0.0093  -0.0511 429 GLU B CD  
3194 O OE1 . GLU B 214 ? 0.9788 0.6745 0.9067 0.0766  0.0003  -0.0539 429 GLU B OE1 
3195 O OE2 . GLU B 214 ? 0.9712 0.7448 0.9392 0.1045  0.0181  -0.0634 429 GLU B OE2 
3196 N N   . VAL B 215 ? 0.8558 0.6264 0.7957 -0.0077 -0.0163 -0.0069 430 VAL B N   
3197 C CA  . VAL B 215 ? 0.9029 0.6702 0.8346 -0.0320 -0.0258 -0.0018 430 VAL B CA  
3198 C C   . VAL B 215 ? 0.9650 0.6741 0.8743 -0.0399 -0.0299 -0.0078 430 VAL B C   
3199 O O   . VAL B 215 ? 1.0004 0.6715 0.8916 -0.0285 -0.0276 -0.0228 430 VAL B O   
3200 C CB  . VAL B 215 ? 0.8818 0.6772 0.8030 -0.0485 -0.0302 -0.0070 430 VAL B CB  
3201 C CG1 . VAL B 215 ? 0.8596 0.7025 0.7959 -0.0369 -0.0280 0.0024  430 VAL B CG1 
3202 C CG2 . VAL B 215 ? 0.9492 0.7171 0.8438 -0.0496 -0.0290 -0.0262 430 VAL B CG2 
3203 N N   . SER B 216 ? 0.9921 0.6918 0.8990 -0.0590 -0.0354 0.0037  431 SER B N   
3204 C CA  . SER B 216 ? 1.0819 0.7161 0.9587 -0.0744 -0.0400 0.0014  431 SER B CA  
3205 C C   . SER B 216 ? 1.1391 0.7728 0.9975 -0.1109 -0.0450 -0.0087 431 SER B C   
3206 O O   . SER B 216 ? 1.1210 0.8165 0.9948 -0.1238 -0.0467 -0.0090 431 SER B O   
3207 C CB  . SER B 216 ? 1.0742 0.6957 0.9520 -0.0804 -0.0422 0.0215  431 SER B CB  
3208 O OG  . SER B 216 ? 1.1270 0.6858 0.9699 -0.1077 -0.0466 0.0231  431 SER B OG  
3209 N N   . THR B 217 ? 1.2197 0.7819 1.0429 -0.1268 -0.0485 -0.0179 432 THR B N   
3210 C CA  . THR B 217 ? 1.3129 0.8678 1.1146 -0.1652 -0.0539 -0.0325 432 THR B CA  
3211 C C   . THR B 217 ? 1.3469 0.9373 1.1559 -0.2078 -0.0571 -0.0189 432 THR B C   
3212 O O   . THR B 217 ? 1.2965 0.9160 1.1254 -0.2049 -0.0544 0.0016  432 THR B O   
3213 C CB  . THR B 217 ? 1.3560 0.8115 1.1128 -0.1681 -0.0562 -0.0489 432 THR B CB  
3214 O OG1 . THR B 217 ? 1.4064 0.7994 1.1386 -0.1940 -0.0590 -0.0347 432 THR B OG1 
3215 C CG2 . THR B 217 ? 1.3036 0.7281 1.0599 -0.1170 -0.0513 -0.0546 432 THR B CG2 
3216 N N   . SER B 218 ? 1.5766 1.1726 1.3701 -0.2492 -0.0625 -0.0326 433 SER B N   
3217 C CA  . SER B 218 ? 1.5626 1.2071 1.3658 -0.2941 -0.0645 -0.0231 433 SER B CA  
3218 C C   . SER B 218 ? 1.5767 1.1579 1.3587 -0.3139 -0.0610 -0.0038 433 SER B C   
3219 O O   . SER B 218 ? 1.5394 1.1619 1.3423 -0.3115 -0.0568 0.0173  433 SER B O   
3220 C CB  . SER B 218 ? 1.5986 1.2581 1.3863 -0.3398 -0.0717 -0.0449 433 SER B CB  
3221 O OG  . SER B 218 ? 1.6749 1.4186 1.4857 -0.3252 -0.0765 -0.0574 433 SER B OG  
3222 N N   . GLU B 219 ? 1.4858 0.9618 1.2210 -0.3320 -0.0629 -0.0112 434 GLU B N   
3223 C CA  . GLU B 219 ? 1.4467 0.8442 1.1475 -0.3573 -0.0608 0.0080  434 GLU B CA  
3224 C C   . GLU B 219 ? 1.4100 0.7802 1.1138 -0.3122 -0.0574 0.0310  434 GLU B C   
3225 O O   . GLU B 219 ? 1.4359 0.7562 1.1133 -0.3300 -0.0555 0.0530  434 GLU B O   
3226 C CB  . GLU B 219 ? 1.4936 0.7681 1.1361 -0.3792 -0.0651 -0.0077 434 GLU B CB  
3227 C CG  . GLU B 219 ? 1.5354 0.7753 1.1689 -0.3387 -0.0686 -0.0349 434 GLU B CG  
3228 C CD  . GLU B 219 ? 1.5968 0.7154 1.1701 -0.3605 -0.0734 -0.0557 434 GLU B CD  
3229 O OE1 . GLU B 219 ? 1.5862 0.6774 1.1378 -0.4070 -0.0728 -0.0506 434 GLU B OE1 
3230 O OE2 . GLU B 219 ? 1.6705 0.7453 1.2292 -0.3195 -0.0752 -0.0771 434 GLU B OE2 
3231 N N   . ARG B 220 ? 1.3090 0.7112 1.0413 -0.2577 -0.0566 0.0268  435 ARG B N   
3232 C CA  . ARG B 220 ? 1.2443 0.6360 0.9850 -0.2149 -0.0547 0.0449  435 ARG B CA  
3233 C C   . ARG B 220 ? 1.2033 0.7034 0.9942 -0.2024 -0.0508 0.0549  435 ARG B C   
3234 O O   . ARG B 220 ? 1.1913 0.7613 1.0136 -0.1941 -0.0500 0.0422  435 ARG B O   
3235 C CB  . ARG B 220 ? 1.2187 0.5683 0.9548 -0.1628 -0.0561 0.0307  435 ARG B CB  
3236 C CG  . ARG B 220 ? 1.2825 0.5211 0.9675 -0.1625 -0.0605 0.0161  435 ARG B CG  
3237 C CD  . ARG B 220 ? 1.2726 0.4948 0.9624 -0.1040 -0.0602 0.0008  435 ARG B CD  
3238 N NE  . ARG B 220 ? 1.2575 0.4677 0.9517 -0.0642 -0.0616 0.0190  435 ARG B NE  
3239 C CZ  . ARG B 220 ? 1.2558 0.4278 0.9408 -0.0137 -0.0639 0.0100  435 ARG B CZ  
3240 N NH1 . ARG B 220 ? 1.2825 0.4258 0.9546 0.0059  -0.0630 -0.0181 435 ARG B NH1 
3241 N NH2 . ARG B 220 ? 1.2414 0.4106 0.9303 0.0197  -0.0674 0.0278  435 ARG B NH2 
3242 N N   . GLY B 221 ? 1.1472 0.6560 0.9411 -0.1983 -0.0488 0.0774  436 GLY B N   
3243 C CA  . GLY B 221 ? 1.1051 0.7064 0.9409 -0.1848 -0.0454 0.0851  436 GLY B CA  
3244 C C   . GLY B 221 ? 1.0707 0.6831 0.9284 -0.1336 -0.0453 0.0827  436 GLY B C   
3245 O O   . GLY B 221 ? 1.0735 0.6372 0.9205 -0.1065 -0.0473 0.0729  436 GLY B O   
3246 N N   . ALA B 222 ? 0.9871 0.6677 0.8757 -0.1213 -0.0428 0.0901  437 ALA B N   
3247 C CA  . ALA B 222 ? 0.9625 0.6627 0.8746 -0.0801 -0.0422 0.0866  437 ALA B CA  
3248 C C   . ALA B 222 ? 0.9684 0.6106 0.8601 -0.0557 -0.0460 0.0943  437 ALA B C   
3249 O O   . ALA B 222 ? 1.0262 0.6266 0.8882 -0.0677 -0.0488 0.1106  437 ALA B O   
3250 C CB  . ALA B 222 ? 0.9167 0.6901 0.8580 -0.0754 -0.0396 0.0927  437 ALA B CB  
3251 N N   . GLN B 223 ? 0.9624 0.6039 0.8680 -0.0209 -0.0463 0.0828  438 GLN B N   
3252 C CA  . GLN B 223 ? 0.9562 0.5613 0.8497 0.0106  -0.0515 0.0874  438 GLN B CA  
3253 C C   . GLN B 223 ? 0.9352 0.5972 0.8669 0.0400  -0.0490 0.0765  438 GLN B C   
3254 O O   . GLN B 223 ? 0.8855 0.5921 0.8431 0.0351  -0.0427 0.0653  438 GLN B O   
3255 C CB  . GLN B 223 ? 1.0199 0.5464 0.8803 0.0218  -0.0549 0.0786  438 GLN B CB  
3256 C CG  . GLN B 223 ? 1.0922 0.5480 0.9154 0.0446  -0.0638 0.0918  438 GLN B CG  
3257 C CD  . GLN B 223 ? 1.1656 0.5231 0.9407 0.0381  -0.0672 0.0870  438 GLN B CD  
3258 O OE1 . GLN B 223 ? 1.2230 0.5017 0.9539 0.0478  -0.0747 0.1010  438 GLN B OE1 
3259 N NE2 . GLN B 223 ? 1.1695 0.5263 0.9483 0.0228  -0.0623 0.0663  438 GLN B NE2 
3260 N N   . HIS B 224 ? 0.8870 0.5475 0.8200 0.0696  -0.0546 0.0800  439 HIS B N   
3261 C CA  . HIS B 224 ? 0.8811 0.6002 0.8512 0.0919  -0.0521 0.0677  439 HIS B CA  
3262 C C   . HIS B 224 ? 0.8994 0.6035 0.8647 0.1299  -0.0594 0.0639  439 HIS B C   
3263 O O   . HIS B 224 ? 0.9556 0.5995 0.8854 0.1417  -0.0675 0.0741  439 HIS B O   
3264 C CB  . HIS B 224 ? 0.8568 0.6313 0.8483 0.0834  -0.0518 0.0745  439 HIS B CB  
3265 C CG  . HIS B 224 ? 0.8810 0.6419 0.8507 0.0853  -0.0600 0.0932  439 HIS B CG  
3266 N ND1 . HIS B 224 ? 0.8889 0.6454 0.8522 0.1153  -0.0693 0.0968  439 HIS B ND1 
3267 C CD2 . HIS B 224 ? 0.8841 0.6348 0.8327 0.0611  -0.0601 0.1103  439 HIS B CD2 
3268 C CE1 . HIS B 224 ? 0.9011 0.6399 0.8366 0.1100  -0.0753 0.1173  439 HIS B CE1 
3269 N NE2 . HIS B 224 ? 0.9006 0.6364 0.8271 0.0752  -0.0686 0.1258  439 HIS B NE2 
3270 N N   . HIS B 225 ? 0.8886 0.6476 0.8881 0.1491  -0.0564 0.0485  440 HIS B N   
3271 C CA  . HIS B 225 ? 0.9333 0.7026 0.9381 0.1889  -0.0636 0.0408  440 HIS B CA  
3272 C C   . HIS B 225 ? 0.9095 0.7621 0.9572 0.1909  -0.0612 0.0311  440 HIS B C   
3273 O O   . HIS B 225 ? 0.8411 0.7311 0.9149 0.1744  -0.0494 0.0183  440 HIS B O   
3274 C CB  . HIS B 225 ? 0.9556 0.7037 0.9564 0.2092  -0.0592 0.0224  440 HIS B CB  
3275 C CG  . HIS B 225 ? 1.0052 0.7439 0.9981 0.2571  -0.0694 0.0163  440 HIS B CG  
3276 N ND1 . HIS B 225 ? 0.9825 0.7863 1.0032 0.2834  -0.0762 0.0121  440 HIS B ND1 
3277 C CD2 . HIS B 225 ? 1.0675 0.7421 1.0277 0.2865  -0.0748 0.0110  440 HIS B CD2 
3278 C CE1 . HIS B 225 ? 1.0254 0.8108 1.0322 0.3299  -0.0862 0.0061  440 HIS B CE1 
3279 N NE2 . HIS B 225 ? 1.0831 0.7852 1.0514 0.3343  -0.0853 0.0054  440 HIS B NE2 
3280 N N   . ILE B 226 ? 0.8838 0.7615 0.9343 0.2077  -0.0725 0.0379  441 ILE B N   
3281 C CA  . ILE B 226 ? 0.8592 0.8147 0.9473 0.2069  -0.0724 0.0269  441 ILE B CA  
3282 C C   . ILE B 226 ? 0.8429 0.8457 0.9545 0.2412  -0.0765 0.0092  441 ILE B C   
3283 O O   . ILE B 226 ? 0.8976 0.8770 0.9899 0.2778  -0.0883 0.0131  441 ILE B O   
3284 C CB  . ILE B 226 ? 0.8823 0.8497 0.9605 0.2036  -0.0829 0.0413  441 ILE B CB  
3285 C CG1 . ILE B 226 ? 0.8574 0.7904 0.9150 0.1710  -0.0776 0.0570  441 ILE B CG1 
3286 C CG2 . ILE B 226 ? 0.8440 0.8902 0.9600 0.1998  -0.0833 0.0252  441 ILE B CG2 
3287 C CD1 . ILE B 226 ? 0.8688 0.7854 0.8956 0.1727  -0.0880 0.0783  441 ILE B CD1 
3288 N N   . TYR B 227 ? 0.8243 0.8940 0.9760 0.2297  -0.0665 -0.0106 442 TYR B N   
3289 C CA  . TYR B 227 ? 0.7801 0.9179 0.9628 0.2571  -0.0686 -0.0307 442 TYR B CA  
3290 C C   . TYR B 227 ? 0.7463 0.9640 0.9638 0.2432  -0.0712 -0.0415 442 TYR B C   
3291 O O   . TYR B 227 ? 0.7373 0.9548 0.9584 0.2078  -0.0655 -0.0387 442 TYR B O   
3292 C CB  . TYR B 227 ? 0.7808 0.9369 0.9809 0.2529  -0.0516 -0.0488 442 TYR B CB  
3293 C CG  . TYR B 227 ? 0.8330 0.9146 0.9994 0.2647  -0.0481 -0.0445 442 TYR B CG  
3294 C CD1 . TYR B 227 ? 0.8413 0.8632 0.9839 0.2333  -0.0399 -0.0331 442 TYR B CD1 
3295 C CD2 . TYR B 227 ? 0.8723 0.9452 1.0298 0.3089  -0.0539 -0.0541 442 TYR B CD2 
3296 C CE1 . TYR B 227 ? 0.8744 0.8314 0.9858 0.2404  -0.0377 -0.0324 442 TYR B CE1 
3297 C CE2 . TYR B 227 ? 0.9247 0.9233 1.0476 0.3186  -0.0512 -0.0536 442 TYR B CE2 
3298 C CZ  . TYR B 227 ? 0.9193 0.8605 1.0193 0.2813  -0.0430 -0.0431 442 TYR B CZ  
3299 O OH  . TYR B 227 ? 0.9871 0.8571 1.0520 0.2877  -0.0412 -0.0458 442 TYR B OH  
3300 N N   . ARG B 228 ? 0.7374 1.0251 0.9799 0.2726  -0.0805 -0.0563 443 ARG B N   
3301 C CA  . ARG B 228 ? 0.7122 1.0907 0.9948 0.2560  -0.0812 -0.0744 443 ARG B CA  
3302 C C   . ARG B 228 ? 0.7111 1.1436 1.0299 0.2325  -0.0612 -0.0964 443 ARG B C   
3303 O O   . ARG B 228 ? 0.7199 1.1746 1.0488 0.2572  -0.0560 -0.1073 443 ARG B O   
3304 C CB  . ARG B 228 ? 0.7130 1.1549 1.0075 0.2987  -0.1022 -0.0814 443 ARG B CB  
3305 C CG  . ARG B 228 ? 0.7382 1.1740 1.0126 0.3028  -0.1206 -0.0675 443 ARG B CG  
3306 C CD  . ARG B 228 ? 0.7845 1.2859 1.0676 0.3518  -0.1431 -0.0742 443 ARG B CD  
3307 N NE  . ARG B 228 ? 0.8304 1.2991 1.0947 0.4038  -0.1497 -0.0685 443 ARG B NE  
3308 C CZ  . ARG B 228 ? 0.7890 1.3203 1.0820 0.4307  -0.1481 -0.0898 443 ARG B CZ  
3309 N NH1 . ARG B 228 ? 0.7625 1.4002 1.1066 0.4087  -0.1402 -0.1171 443 ARG B NH1 
3310 N NH2 . ARG B 228 ? 0.8239 1.2976 1.0849 0.4690  -0.1505 -0.0827 443 ARG B NH2 
3311 N N   . LEU B 229 ? 0.7124 1.1632 1.0468 0.1852  -0.0494 -0.1030 444 LEU B N   
3312 C CA  . LEU B 229 ? 0.7439 1.2476 1.1091 0.1554  -0.0294 -0.1219 444 LEU B CA  
3313 C C   . LEU B 229 ? 0.7436 1.3613 1.1537 0.1581  -0.0347 -0.1467 444 LEU B C   
3314 O O   . LEU B 229 ? 0.7287 1.3785 1.1493 0.1427  -0.0452 -0.1526 444 LEU B O   
3315 C CB  . LEU B 229 ? 0.7432 1.2064 1.0986 0.1035  -0.0147 -0.1169 444 LEU B CB  
3316 C CG  . LEU B 229 ? 0.7620 1.1349 1.0818 0.0929  -0.0039 -0.0981 444 LEU B CG  
3317 C CD1 . LEU B 229 ? 0.7564 1.0984 1.0674 0.0478  0.0073  -0.0950 444 LEU B CD1 
3318 C CD2 . LEU B 229 ? 0.7860 1.1595 1.1049 0.1037  0.0100  -0.1018 444 LEU B CD2 
3319 N N   . VAL B 230 ? 0.7173 1.4018 1.1545 0.1768  -0.0271 -0.1637 445 VAL B N   
3320 C CA  . VAL B 230 ? 0.6893 1.5000 1.1747 0.1849  -0.0314 -0.1904 445 VAL B CA  
3321 C C   . VAL B 230 ? 0.7205 1.5933 1.2362 0.1482  -0.0045 -0.2090 445 VAL B C   
3322 O O   . VAL B 230 ? 0.7330 1.5486 1.2280 0.1307  0.0149  -0.1999 445 VAL B O   
3323 C CB  . VAL B 230 ? 0.6977 1.5456 1.1876 0.2554  -0.0504 -0.1950 445 VAL B CB  
3324 C CG1 . VAL B 230 ? 0.6471 1.4303 1.1004 0.2884  -0.0763 -0.1732 445 VAL B CG1 
3325 C CG2 . VAL B 230 ? 0.7102 1.5199 1.1847 0.2842  -0.0384 -0.1935 445 VAL B CG2 
3326 N N   . ARG B 231 ? 0.6960 1.6934 1.2605 0.1355  -0.0034 -0.2356 446 ARG B N   
3327 C CA  . ARG B 231 ? 0.7181 1.7909 1.3144 0.0943  0.0238  -0.2547 446 ARG B CA  
3328 C C   . ARG B 231 ? 0.7965 1.9622 1.4109 0.1112  0.0157  -0.2735 446 ARG B C   
3329 O O   . ARG B 231 ? 0.8075 2.0374 1.4417 0.0705  0.0178  -0.2888 446 ARG B O   
3330 C CB  . ARG B 231 ? 0.7172 1.7643 1.3091 0.0171  0.0396  -0.2531 446 ARG B CB  
3331 C CG  . ARG B 231 ? 0.7469 1.8684 1.3646 -0.0339 0.0676  -0.2702 446 ARG B CG  
3332 C CD  . ARG B 231 ? 0.7476 1.8076 1.3461 -0.1066 0.0834  -0.2622 446 ARG B CD  
3333 N NE  . ARG B 231 ? 0.7219 1.8102 1.3358 -0.1361 0.0690  -0.2753 446 ARG B NE  
3334 C CZ  . ARG B 231 ? 0.7629 1.7910 1.3556 -0.1961 0.0771  -0.2720 446 ARG B CZ  
3335 N NH1 . ARG B 231 ? 0.8194 1.7531 1.3731 -0.2310 0.0984  -0.2529 446 ARG B NH1 
3336 N NH2 . ARG B 231 ? 0.7450 1.7974 1.3479 -0.2175 0.0616  -0.2871 446 ARG B NH2 
3337 N N   . ASP B 232 ? 0.9049 2.0744 1.5093 0.1730  0.0059  -0.2737 447 ASP B N   
3338 C CA  . ASP B 232 ? 0.9039 2.1593 1.5224 0.2007  -0.0044 -0.2917 447 ASP B CA  
3339 C C   . ASP B 232 ? 0.9126 2.2559 1.5584 0.1602  0.0200  -0.3127 447 ASP B C   
3340 O O   . ASP B 232 ? 0.9123 2.2567 1.5669 0.0962  0.0418  -0.3136 447 ASP B O   
3341 C CB  . ASP B 232 ? 0.9278 2.1485 1.5217 0.2759  -0.0186 -0.2857 447 ASP B CB  
3342 C CG  . ASP B 232 ? 0.9808 2.0815 1.5382 0.3025  -0.0264 -0.2603 447 ASP B CG  
3343 O OD1 . ASP B 232 ? 0.9842 2.0357 1.5321 0.2941  -0.0080 -0.2550 447 ASP B OD1 
3344 O OD2 . ASP B 232 ? 0.9877 2.0444 1.5234 0.3299  -0.0503 -0.2458 447 ASP B OD2 
# 
