data_8RWS
# 
_entry.id   8RWS 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8RWS         pdb_00008rws 10.2210/pdb8rws/pdb 
WWPDB D_1292136353 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8RWS 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-05 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jim.spencer@bristol.ac.uk 
_pdbx_contact_author.name_first         James 
_pdbx_contact_author.name_last          Spencer 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-4602-0571 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Beer, M.'       1 0000-0002-3879-3339 
'Hinchliffe, P.' 2 ?                   
'Tooke, C.L.'    3 ?                   
'Spencer, J.'    4 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Chem Sci' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-6520 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                17232 
_citation.page_last                 17244 
_citation.title                     
'Dynamical responses predict a distal site that modulates activity in an antibiotic resistance enzyme.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1039/d4sc03295k 
_citation.pdbx_database_id_PubMed   39364073 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Beer, M.'         1 0000-0002-3879-3339 
primary 'Oliveira, A.S.F.' 2 0000-0001-8753-4950 
primary 'Tooke, C.L.'      3 ?                   
primary 'Hinchliffe, P.'   4 0000-0001-8611-4743 
primary 'Tsz Yan Li, A.'   5 ?                   
primary 'Balega, B.'       6 ?                   
primary 'Spencer, J.'      7 0000-0002-4602-0571 
primary 'Mulholland, A.J.' 8 0000-0003-1015-4567 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Carbapenem-hydrolyzing beta-lactamase KPC' 30863.682 1   3.5.2.6 ? ? ? 
2 non-polymer syn 'SULFATE ION' 96.063    3   ?       ? ? ? 
3 non-polymer syn 
;(2S,3R,4R)-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid
;
385.478   1   ?       ? ? ? 
4 non-polymer syn 
;(4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid
;
385.478   1   ?       ? ? ? 
5 water       nat water 18.015    291 ?       ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Carbapenem-hydrolyzing beta-lactamase KPC-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MGSSHHHHHHSSGLVPRGSHMLTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARS
QQQADLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
WQLELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTA
NDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGVNGQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MGSSHHHHHHSSGLVPRGSHMLTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARS
QQQADLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDR
WQLELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTA
NDYAVVWPTGRAPIVLAVYTRAPNKDDKHSEAVIAAAARLALEGLGVNGQ
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 
;(2S,3R,4R)-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid
;
O2F 
4 
;(4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid
;
MER 
5 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   SER n 
1 4   SER n 
1 5   HIS n 
1 6   HIS n 
1 7   HIS n 
1 8   HIS n 
1 9   HIS n 
1 10  HIS n 
1 11  SER n 
1 12  SER n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  PRO n 
1 17  ARG n 
1 18  GLY n 
1 19  SER n 
1 20  HIS n 
1 21  MET n 
1 22  LEU n 
1 23  THR n 
1 24  ASN n 
1 25  LEU n 
1 26  VAL n 
1 27  ALA n 
1 28  GLU n 
1 29  PRO n 
1 30  PHE n 
1 31  ALA n 
1 32  LYS n 
1 33  LEU n 
1 34  GLU n 
1 35  GLN n 
1 36  ASP n 
1 37  PHE n 
1 38  GLY n 
1 39  GLY n 
1 40  SER n 
1 41  ILE n 
1 42  GLY n 
1 43  VAL n 
1 44  TYR n 
1 45  ALA n 
1 46  MET n 
1 47  ASP n 
1 48  THR n 
1 49  GLY n 
1 50  SER n 
1 51  GLY n 
1 52  ALA n 
1 53  THR n 
1 54  VAL n 
1 55  SER n 
1 56  TYR n 
1 57  ARG n 
1 58  ALA n 
1 59  GLU n 
1 60  GLU n 
1 61  ARG n 
1 62  PHE n 
1 63  PRO n 
1 64  LEU n 
1 65  CYS n 
1 66  SER n 
1 67  SER n 
1 68  PHE n 
1 69  LYS n 
1 70  GLY n 
1 71  PHE n 
1 72  LEU n 
1 73  ALA n 
1 74  ALA n 
1 75  ALA n 
1 76  VAL n 
1 77  LEU n 
1 78  ALA n 
1 79  ARG n 
1 80  SER n 
1 81  GLN n 
1 82  GLN n 
1 83  GLN n 
1 84  ALA n 
1 85  ASP n 
1 86  LEU n 
1 87  LEU n 
1 88  ASP n 
1 89  THR n 
1 90  PRO n 
1 91  ILE n 
1 92  ARG n 
1 93  TYR n 
1 94  GLY n 
1 95  LYS n 
1 96  ASN n 
1 97  ALA n 
1 98  LEU n 
1 99  VAL n 
1 100 PRO n 
1 101 TRP n 
1 102 SER n 
1 103 PRO n 
1 104 ILE n 
1 105 SER n 
1 106 GLU n 
1 107 LYS n 
1 108 TYR n 
1 109 LEU n 
1 110 THR n 
1 111 THR n 
1 112 GLY n 
1 113 MET n 
1 114 THR n 
1 115 VAL n 
1 116 ALA n 
1 117 GLU n 
1 118 LEU n 
1 119 SER n 
1 120 ALA n 
1 121 ALA n 
1 122 ALA n 
1 123 VAL n 
1 124 GLN n 
1 125 TYR n 
1 126 SER n 
1 127 ASP n 
1 128 ASN n 
1 129 ALA n 
1 130 ALA n 
1 131 ALA n 
1 132 ASN n 
1 133 LEU n 
1 134 LEU n 
1 135 LEU n 
1 136 LYS n 
1 137 GLU n 
1 138 LEU n 
1 139 GLY n 
1 140 GLY n 
1 141 PRO n 
1 142 ALA n 
1 143 GLY n 
1 144 LEU n 
1 145 THR n 
1 146 ALA n 
1 147 PHE n 
1 148 MET n 
1 149 ARG n 
1 150 SER n 
1 151 ILE n 
1 152 GLY n 
1 153 ASP n 
1 154 THR n 
1 155 THR n 
1 156 PHE n 
1 157 ARG n 
1 158 LEU n 
1 159 ASP n 
1 160 ARG n 
1 161 TRP n 
1 162 GLN n 
1 163 LEU n 
1 164 GLU n 
1 165 LEU n 
1 166 ASN n 
1 167 SER n 
1 168 ALA n 
1 169 ILE n 
1 170 PRO n 
1 171 GLY n 
1 172 ASP n 
1 173 ALA n 
1 174 ARG n 
1 175 ASP n 
1 176 THR n 
1 177 SER n 
1 178 SER n 
1 179 PRO n 
1 180 ARG n 
1 181 ALA n 
1 182 VAL n 
1 183 THR n 
1 184 GLU n 
1 185 SER n 
1 186 LEU n 
1 187 GLN n 
1 188 LYS n 
1 189 LEU n 
1 190 THR n 
1 191 LEU n 
1 192 GLY n 
1 193 SER n 
1 194 ALA n 
1 195 LEU n 
1 196 ALA n 
1 197 ALA n 
1 198 PRO n 
1 199 GLN n 
1 200 ARG n 
1 201 GLN n 
1 202 GLN n 
1 203 PHE n 
1 204 VAL n 
1 205 ASP n 
1 206 TRP n 
1 207 LEU n 
1 208 LYS n 
1 209 GLY n 
1 210 ASN n 
1 211 THR n 
1 212 THR n 
1 213 GLY n 
1 214 ASN n 
1 215 HIS n 
1 216 ARG n 
1 217 ILE n 
1 218 ARG n 
1 219 ALA n 
1 220 ALA n 
1 221 VAL n 
1 222 PRO n 
1 223 ALA n 
1 224 ASP n 
1 225 TRP n 
1 226 ALA n 
1 227 VAL n 
1 228 GLY n 
1 229 ASP n 
1 230 LYS n 
1 231 THR n 
1 232 GLY n 
1 233 THR n 
1 234 CYS n 
1 235 GLY n 
1 236 VAL n 
1 237 TYR n 
1 238 GLY n 
1 239 THR n 
1 240 ALA n 
1 241 ASN n 
1 242 ASP n 
1 243 TYR n 
1 244 ALA n 
1 245 VAL n 
1 246 VAL n 
1 247 TRP n 
1 248 PRO n 
1 249 THR n 
1 250 GLY n 
1 251 ARG n 
1 252 ALA n 
1 253 PRO n 
1 254 ILE n 
1 255 VAL n 
1 256 LEU n 
1 257 ALA n 
1 258 VAL n 
1 259 TYR n 
1 260 THR n 
1 261 ARG n 
1 262 ALA n 
1 263 PRO n 
1 264 ASN n 
1 265 LYS n 
1 266 ASP n 
1 267 ASP n 
1 268 LYS n 
1 269 HIS n 
1 270 SER n 
1 271 GLU n 
1 272 ALA n 
1 273 VAL n 
1 274 ILE n 
1 275 ALA n 
1 276 ALA n 
1 277 ALA n 
1 278 ALA n 
1 279 ARG n 
1 280 LEU n 
1 281 ALA n 
1 282 LEU n 
1 283 GLU n 
1 284 GLY n 
1 285 LEU n 
1 286 GLY n 
1 287 VAL n 
1 288 ASN n 
1 289 GLY n 
1 290 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   290 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'bla, kpc, kpc1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ?                       'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE ?                       'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                       'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                       'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE ?                       'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                       'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                       'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE ?                       'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE ?                       'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER ?                       'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                       'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE ?                       'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE ?                       'C6 H15 N2 O2 1'  147.195 
MER non-polymer         . 
;(4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid
;
'Meropenem, bound form' 'C17 H27 N3 O5 S' 385.478 
MET 'L-peptide linking' y METHIONINE ?                       'C5 H11 N O2 S'   149.211 
O2F non-polymer         . 
;(2S,3R,4R)-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-2-[(2S,3R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2H-pyrrole-5-carboxylic acid
;
'Meropenem, bound form' 'C17 H27 N3 O5 S' 385.478 
PHE 'L-peptide linking' y PHENYLALANINE ?                       'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE ?                       'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE ?                       'C3 H7 N O3'      105.093 
SO4 non-polymer         . 'SULFATE ION' ?                       'O4 S -2'         96.063  
THR 'L-peptide linking' y THREONINE ?                       'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                       'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE ?                       'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE ?                       'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   4   ?   ?   ?   A . n 
A 1 2   GLY 2   5   ?   ?   ?   A . n 
A 1 3   SER 3   6   ?   ?   ?   A . n 
A 1 4   SER 4   7   ?   ?   ?   A . n 
A 1 5   HIS 5   8   ?   ?   ?   A . n 
A 1 6   HIS 6   9   ?   ?   ?   A . n 
A 1 7   HIS 7   10  ?   ?   ?   A . n 
A 1 8   HIS 8   11  ?   ?   ?   A . n 
A 1 9   HIS 9   12  ?   ?   ?   A . n 
A 1 10  HIS 10  13  ?   ?   ?   A . n 
A 1 11  SER 11  14  ?   ?   ?   A . n 
A 1 12  SER 12  15  ?   ?   ?   A . n 
A 1 13  GLY 13  16  ?   ?   ?   A . n 
A 1 14  LEU 14  17  ?   ?   ?   A . n 
A 1 15  VAL 15  18  ?   ?   ?   A . n 
A 1 16  PRO 16  19  ?   ?   ?   A . n 
A 1 17  ARG 17  20  ?   ?   ?   A . n 
A 1 18  GLY 18  21  ?   ?   ?   A . n 
A 1 19  SER 19  22  ?   ?   ?   A . n 
A 1 20  HIS 20  23  ?   ?   ?   A . n 
A 1 21  MET 21  24  ?   ?   ?   A . n 
A 1 22  LEU 22  25  ?   ?   ?   A . n 
A 1 23  THR 23  26  26  THR THR A . n 
A 1 24  ASN 24  27  27  ASN ASN A . n 
A 1 25  LEU 25  28  28  LEU LEU A . n 
A 1 26  VAL 26  29  29  VAL VAL A . n 
A 1 27  ALA 27  30  30  ALA ALA A . n 
A 1 28  GLU 28  31  31  GLU GLU A . n 
A 1 29  PRO 29  32  32  PRO PRO A . n 
A 1 30  PHE 30  33  33  PHE PHE A . n 
A 1 31  ALA 31  34  34  ALA ALA A . n 
A 1 32  LYS 32  35  35  LYS LYS A . n 
A 1 33  LEU 33  36  36  LEU LEU A . n 
A 1 34  GLU 34  37  37  GLU GLU A . n 
A 1 35  GLN 35  38  38  GLN GLN A . n 
A 1 36  ASP 36  39  39  ASP ASP A . n 
A 1 37  PHE 37  40  40  PHE PHE A . n 
A 1 38  GLY 38  41  41  GLY GLY A . n 
A 1 39  GLY 39  42  42  GLY GLY A . n 
A 1 40  SER 40  43  43  SER SER A . n 
A 1 41  ILE 41  44  44  ILE ILE A . n 
A 1 42  GLY 42  45  45  GLY GLY A . n 
A 1 43  VAL 43  46  46  VAL VAL A . n 
A 1 44  TYR 44  47  47  TYR TYR A . n 
A 1 45  ALA 45  48  48  ALA ALA A . n 
A 1 46  MET 46  49  49  MET MET A . n 
A 1 47  ASP 47  50  50  ASP ASP A . n 
A 1 48  THR 48  51  51  THR THR A . n 
A 1 49  GLY 49  52  52  GLY GLY A . n 
A 1 50  SER 50  53  53  SER SER A . n 
A 1 51  GLY 51  54  54  GLY GLY A . n 
A 1 52  ALA 52  55  55  ALA ALA A . n 
A 1 53  THR 53  56  56  THR THR A . n 
A 1 54  VAL 54  57  57  VAL VAL A . n 
A 1 55  SER 55  59  59  SER SER A . n 
A 1 56  TYR 56  60  60  TYR TYR A . n 
A 1 57  ARG 57  61  61  ARG ARG A . n 
A 1 58  ALA 58  62  62  ALA ALA A . n 
A 1 59  GLU 59  63  63  GLU GLU A . n 
A 1 60  GLU 60  64  64  GLU GLU A . n 
A 1 61  ARG 61  65  65  ARG ARG A . n 
A 1 62  PHE 62  66  66  PHE PHE A . n 
A 1 63  PRO 63  67  67  PRO PRO A . n 
A 1 64  LEU 64  68  68  LEU LEU A . n 
A 1 65  CYS 65  69  69  CYS CYS A . n 
A 1 66  SER 66  70  70  SER SER A . n 
A 1 67  SER 67  71  71  SER SER A . n 
A 1 68  PHE 68  72  72  PHE PHE A . n 
A 1 69  LYS 69  73  73  LYS LYS A . n 
A 1 70  GLY 70  74  74  GLY GLY A . n 
A 1 71  PHE 71  75  75  PHE PHE A . n 
A 1 72  LEU 72  76  76  LEU LEU A . n 
A 1 73  ALA 73  77  77  ALA ALA A . n 
A 1 74  ALA 74  78  78  ALA ALA A . n 
A 1 75  ALA 75  79  79  ALA ALA A . n 
A 1 76  VAL 76  80  80  VAL VAL A . n 
A 1 77  LEU 77  81  81  LEU LEU A . n 
A 1 78  ALA 78  82  82  ALA ALA A . n 
A 1 79  ARG 79  83  83  ARG ARG A . n 
A 1 80  SER 80  84  84  SER SER A . n 
A 1 81  GLN 81  85  85  GLN GLN A . n 
A 1 82  GLN 82  86  86  GLN GLN A . n 
A 1 83  GLN 83  87  87  GLN GLN A . n 
A 1 84  ALA 84  88  88  ALA ALA A . n 
A 1 85  ASP 85  89  89  ASP ASP A . n 
A 1 86  LEU 86  90  90  LEU LEU A . n 
A 1 87  LEU 87  91  91  LEU LEU A . n 
A 1 88  ASP 88  92  92  ASP ASP A . n 
A 1 89  THR 89  93  93  THR THR A . n 
A 1 90  PRO 90  94  94  PRO PRO A . n 
A 1 91  ILE 91  95  95  ILE ILE A . n 
A 1 92  ARG 92  96  96  ARG ARG A . n 
A 1 93  TYR 93  97  97  TYR TYR A . n 
A 1 94  GLY 94  98  98  GLY GLY A . n 
A 1 95  LYS 95  99  99  LYS LYS A . n 
A 1 96  ASN 96  100 100 ASN ASN A . n 
A 1 97  ALA 97  101 101 ALA ALA A . n 
A 1 98  LEU 98  102 102 LEU LEU A . n 
A 1 99  VAL 99  103 103 VAL VAL A . n 
A 1 100 PRO 100 104 104 PRO PRO A . n 
A 1 101 TRP 101 105 105 TRP TRP A . n 
A 1 102 SER 102 106 106 SER SER A . n 
A 1 103 PRO 103 107 107 PRO PRO A . n 
A 1 104 ILE 104 108 108 ILE ILE A . n 
A 1 105 SER 105 109 109 SER SER A . n 
A 1 106 GLU 106 110 110 GLU GLU A . n 
A 1 107 LYS 107 111 111 LYS LYS A . n 
A 1 108 TYR 108 112 112 TYR TYR A . n 
A 1 109 LEU 109 113 113 LEU LEU A . n 
A 1 110 THR 110 114 114 THR THR A . n 
A 1 111 THR 111 115 115 THR THR A . n 
A 1 112 GLY 112 116 116 GLY GLY A . n 
A 1 113 MET 113 117 117 MET MET A . n 
A 1 114 THR 114 118 118 THR THR A . n 
A 1 115 VAL 115 119 119 VAL VAL A . n 
A 1 116 ALA 116 120 120 ALA ALA A . n 
A 1 117 GLU 117 121 121 GLU GLU A . n 
A 1 118 LEU 118 122 122 LEU LEU A . n 
A 1 119 SER 119 123 123 SER SER A . n 
A 1 120 ALA 120 124 124 ALA ALA A . n 
A 1 121 ALA 121 125 125 ALA ALA A . n 
A 1 122 ALA 122 126 126 ALA ALA A . n 
A 1 123 VAL 123 127 127 VAL VAL A . n 
A 1 124 GLN 124 128 128 GLN GLN A . n 
A 1 125 TYR 125 129 129 TYR TYR A . n 
A 1 126 SER 126 130 130 SER SER A . n 
A 1 127 ASP 127 131 131 ASP ASP A . n 
A 1 128 ASN 128 132 132 ASN ASN A . n 
A 1 129 ALA 129 133 133 ALA ALA A . n 
A 1 130 ALA 130 134 134 ALA ALA A . n 
A 1 131 ALA 131 135 135 ALA ALA A . n 
A 1 132 ASN 132 136 136 ASN ASN A . n 
A 1 133 LEU 133 137 137 LEU LEU A . n 
A 1 134 LEU 134 138 138 LEU LEU A . n 
A 1 135 LEU 135 139 139 LEU LEU A . n 
A 1 136 LYS 136 140 140 LYS LYS A . n 
A 1 137 GLU 137 141 141 GLU GLU A . n 
A 1 138 LEU 138 142 142 LEU LEU A . n 
A 1 139 GLY 139 143 143 GLY GLY A . n 
A 1 140 GLY 140 144 144 GLY GLY A . n 
A 1 141 PRO 141 145 145 PRO PRO A . n 
A 1 142 ALA 142 146 146 ALA ALA A . n 
A 1 143 GLY 143 147 147 GLY GLY A . n 
A 1 144 LEU 144 148 148 LEU LEU A . n 
A 1 145 THR 145 149 149 THR THR A . n 
A 1 146 ALA 146 150 150 ALA ALA A . n 
A 1 147 PHE 147 151 151 PHE PHE A . n 
A 1 148 MET 148 152 152 MET MET A . n 
A 1 149 ARG 149 153 153 ARG ARG A . n 
A 1 150 SER 150 154 154 SER SER A . n 
A 1 151 ILE 151 155 155 ILE ILE A . n 
A 1 152 GLY 152 156 156 GLY GLY A . n 
A 1 153 ASP 153 157 157 ASP ASP A . n 
A 1 154 THR 154 158 158 THR THR A . n 
A 1 155 THR 155 159 159 THR THR A . n 
A 1 156 PHE 156 160 160 PHE PHE A . n 
A 1 157 ARG 157 161 161 ARG ARG A . n 
A 1 158 LEU 158 162 162 LEU LEU A . n 
A 1 159 ASP 159 163 163 ASP ASP A . n 
A 1 160 ARG 160 164 164 ARG ARG A . n 
A 1 161 TRP 161 165 165 TRP TRP A . n 
A 1 162 GLN 162 166 166 GLN GLN A . n 
A 1 163 LEU 163 167 167 LEU LEU A . n 
A 1 164 GLU 164 168 168 GLU GLU A . n 
A 1 165 LEU 165 169 169 LEU LEU A . n 
A 1 166 ASN 166 170 170 ASN ASN A . n 
A 1 167 SER 167 171 171 SER SER A . n 
A 1 168 ALA 168 172 172 ALA ALA A . n 
A 1 169 ILE 169 173 173 ILE ILE A . n 
A 1 170 PRO 170 174 174 PRO PRO A . n 
A 1 171 GLY 171 175 175 GLY GLY A . n 
A 1 172 ASP 172 176 176 ASP ASP A . n 
A 1 173 ALA 173 177 177 ALA ALA A . n 
A 1 174 ARG 174 178 178 ARG ARG A . n 
A 1 175 ASP 175 179 179 ASP ASP A . n 
A 1 176 THR 176 180 180 THR THR A . n 
A 1 177 SER 177 181 181 SER SER A . n 
A 1 178 SER 178 182 182 SER SER A . n 
A 1 179 PRO 179 183 183 PRO PRO A . n 
A 1 180 ARG 180 184 184 ARG ARG A . n 
A 1 181 ALA 181 185 185 ALA ALA A . n 
A 1 182 VAL 182 186 186 VAL VAL A . n 
A 1 183 THR 183 187 187 THR THR A . n 
A 1 184 GLU 184 188 188 GLU GLU A . n 
A 1 185 SER 185 189 189 SER SER A . n 
A 1 186 LEU 186 190 190 LEU LEU A . n 
A 1 187 GLN 187 191 191 GLN GLN A . n 
A 1 188 LYS 188 192 192 LYS LYS A . n 
A 1 189 LEU 189 193 193 LEU LEU A . n 
A 1 190 THR 190 194 194 THR THR A . n 
A 1 191 LEU 191 195 195 LEU LEU A . n 
A 1 192 GLY 192 196 196 GLY GLY A . n 
A 1 193 SER 193 197 197 SER SER A . n 
A 1 194 ALA 194 198 198 ALA ALA A . n 
A 1 195 LEU 195 199 199 LEU LEU A . n 
A 1 196 ALA 196 200 200 ALA ALA A . n 
A 1 197 ALA 197 201 201 ALA ALA A . n 
A 1 198 PRO 198 202 202 PRO PRO A . n 
A 1 199 GLN 199 203 203 GLN GLN A . n 
A 1 200 ARG 200 204 204 ARG ARG A . n 
A 1 201 GLN 201 205 205 GLN GLN A . n 
A 1 202 GLN 202 206 206 GLN GLN A . n 
A 1 203 PHE 203 207 207 PHE PHE A . n 
A 1 204 VAL 204 208 208 VAL VAL A . n 
A 1 205 ASP 205 209 209 ASP ASP A . n 
A 1 206 TRP 206 210 210 TRP TRP A . n 
A 1 207 LEU 207 211 211 LEU LEU A . n 
A 1 208 LYS 208 212 212 LYS LYS A . n 
A 1 209 GLY 209 213 213 GLY GLY A . n 
A 1 210 ASN 210 214 214 ASN ASN A . n 
A 1 211 THR 211 215 215 THR THR A . n 
A 1 212 THR 212 216 216 THR THR A . n 
A 1 213 GLY 213 217 217 GLY GLY A . n 
A 1 214 ASN 214 218 218 ASN ASN A . n 
A 1 215 HIS 215 219 219 HIS HIS A . n 
A 1 216 ARG 216 220 220 ARG ARG A . n 
A 1 217 ILE 217 221 221 ILE ILE A . n 
A 1 218 ARG 218 222 222 ARG ARG A . n 
A 1 219 ALA 219 223 223 ALA ALA A . n 
A 1 220 ALA 220 224 224 ALA ALA A . n 
A 1 221 VAL 221 225 225 VAL VAL A . n 
A 1 222 PRO 222 226 226 PRO PRO A . n 
A 1 223 ALA 223 227 227 ALA ALA A . n 
A 1 224 ASP 224 228 228 ASP ASP A . n 
A 1 225 TRP 225 229 229 TRP TRP A . n 
A 1 226 ALA 226 230 230 ALA ALA A . n 
A 1 227 VAL 227 231 231 VAL VAL A . n 
A 1 228 GLY 228 232 232 GLY GLY A . n 
A 1 229 ASP 229 233 233 ASP ASP A . n 
A 1 230 LYS 230 234 234 LYS LYS A . n 
A 1 231 THR 231 235 235 THR THR A . n 
A 1 232 GLY 232 236 236 GLY GLY A . n 
A 1 233 THR 233 237 237 THR THR A . n 
A 1 234 CYS 234 238 238 CYS CYS A . n 
A 1 235 GLY 235 239 239 GLY GLY A . n 
A 1 236 VAL 236 240 240 VAL VAL A . n 
A 1 237 TYR 237 241 241 TYR TYR A . n 
A 1 238 GLY 238 242 242 GLY GLY A . n 
A 1 239 THR 239 243 243 THR THR A . n 
A 1 240 ALA 240 244 244 ALA ALA A . n 
A 1 241 ASN 241 245 245 ASN ASN A . n 
A 1 242 ASP 242 246 246 ASP ASP A . n 
A 1 243 TYR 243 247 247 TYR TYR A . n 
A 1 244 ALA 244 248 248 ALA ALA A . n 
A 1 245 VAL 245 249 249 VAL VAL A . n 
A 1 246 VAL 246 250 250 VAL VAL A . n 
A 1 247 TRP 247 251 251 TRP TRP A . n 
A 1 248 PRO 248 252 252 PRO PRO A . n 
A 1 249 THR 249 254 254 THR THR A . n 
A 1 250 GLY 250 255 255 GLY GLY A . n 
A 1 251 ARG 251 256 256 ARG ARG A . n 
A 1 252 ALA 252 257 257 ALA ALA A . n 
A 1 253 PRO 253 258 258 PRO PRO A . n 
A 1 254 ILE 254 259 259 ILE ILE A . n 
A 1 255 VAL 255 260 260 VAL VAL A . n 
A 1 256 LEU 256 261 261 LEU LEU A . n 
A 1 257 ALA 257 262 262 ALA ALA A . n 
A 1 258 VAL 258 263 263 VAL VAL A . n 
A 1 259 TYR 259 264 264 TYR TYR A . n 
A 1 260 THR 260 265 265 THR THR A . n 
A 1 261 ARG 261 266 266 ARG ARG A . n 
A 1 262 ALA 262 267 267 ALA ALA A . n 
A 1 263 PRO 263 268 268 PRO PRO A . n 
A 1 264 ASN 264 269 269 ASN ASN A . n 
A 1 265 LYS 265 270 270 LYS LYS A . n 
A 1 266 ASP 266 271 271 ASP ASP A . n 
A 1 267 ASP 267 272 272 ASP ASP A . n 
A 1 268 LYS 268 273 273 LYS LYS A . n 
A 1 269 HIS 269 274 274 HIS HIS A . n 
A 1 270 SER 270 275 275 SER SER A . n 
A 1 271 GLU 271 276 276 GLU GLU A . n 
A 1 272 ALA 272 277 277 ALA ALA A . n 
A 1 273 VAL 273 278 278 VAL VAL A . n 
A 1 274 ILE 274 279 279 ILE ILE A . n 
A 1 275 ALA 275 280 280 ALA ALA A . n 
A 1 276 ALA 276 281 281 ALA ALA A . n 
A 1 277 ALA 277 282 282 ALA ALA A . n 
A 1 278 ALA 278 283 283 ALA ALA A . n 
A 1 279 ARG 279 284 284 ARG ARG A . n 
A 1 280 LEU 280 285 285 LEU LEU A . n 
A 1 281 ALA 281 286 286 ALA ALA A . n 
A 1 282 LEU 282 287 287 LEU LEU A . n 
A 1 283 GLU 283 288 288 GLU GLU A . n 
A 1 284 GLY 284 289 289 GLY GLY A . n 
A 1 285 LEU 285 290 290 LEU LEU A . n 
A 1 286 GLY 286 291 291 GLY GLY A . n 
A 1 287 VAL 287 292 292 VAL VAL A . n 
A 1 288 ASN 288 293 293 ASN ASN A . n 
A 1 289 GLY 289 294 294 GLY GLY A . n 
A 1 290 GLN 290 295 ?   ?   ?   A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 O2F ? ? O2F ? ? 'SUBJECT OF INVESTIGATION' ? 
2 MER ? ? MER ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 SO4 1   301 301 SO4 SO4 A . 
C 2 SO4 1   302 302 SO4 SO4 A . 
D 3 O2F 1   303 305 O2F M1R A . 
E 4 MER 1   304 306 MER MD2 A . 
F 2 SO4 1   305 307 SO4 SO4 A . 
G 5 HOH 1   401 308 HOH HOH A . 
G 5 HOH 2   402 289 HOH HOH A . 
G 5 HOH 3   403 300 HOH HOH A . 
G 5 HOH 4   404 259 HOH HOH A . 
G 5 HOH 5   405 306 HOH HOH A . 
G 5 HOH 6   406 4   HOH HOH A . 
G 5 HOH 7   407 14  HOH HOH A . 
G 5 HOH 8   408 313 HOH HOH A . 
G 5 HOH 9   409 287 HOH HOH A . 
G 5 HOH 10  410 1   HOH HOH A . 
G 5 HOH 11  411 12  HOH HOH A . 
G 5 HOH 12  412 323 HOH HOH A . 
G 5 HOH 13  413 18  HOH HOH A . 
G 5 HOH 14  414 2   HOH HOH A . 
G 5 HOH 15  415 262 HOH HOH A . 
G 5 HOH 16  416 19  HOH HOH A . 
G 5 HOH 17  417 10  HOH HOH A . 
G 5 HOH 18  418 21  HOH HOH A . 
G 5 HOH 19  419 296 HOH HOH A . 
G 5 HOH 20  420 261 HOH HOH A . 
G 5 HOH 21  421 70  HOH HOH A . 
G 5 HOH 22  422 22  HOH HOH A . 
G 5 HOH 23  423 16  HOH HOH A . 
G 5 HOH 24  424 222 HOH HOH A . 
G 5 HOH 25  425 9   HOH HOH A . 
G 5 HOH 26  426 93  HOH HOH A . 
G 5 HOH 27  427 271 HOH HOH A . 
G 5 HOH 28  428 5   HOH HOH A . 
G 5 HOH 29  429 318 HOH HOH A . 
G 5 HOH 30  430 256 HOH HOH A . 
G 5 HOH 31  431 66  HOH HOH A . 
G 5 HOH 32  432 24  HOH HOH A . 
G 5 HOH 33  433 54  HOH HOH A . 
G 5 HOH 34  434 327 HOH HOH A . 
G 5 HOH 35  435 36  HOH HOH A . 
G 5 HOH 36  436 7   HOH HOH A . 
G 5 HOH 37  437 42  HOH HOH A . 
G 5 HOH 38  438 37  HOH HOH A . 
G 5 HOH 39  439 33  HOH HOH A . 
G 5 HOH 40  440 45  HOH HOH A . 
G 5 HOH 41  441 314 HOH HOH A . 
G 5 HOH 42  442 30  HOH HOH A . 
G 5 HOH 43  443 60  HOH HOH A . 
G 5 HOH 44  444 290 HOH HOH A . 
G 5 HOH 45  445 44  HOH HOH A . 
G 5 HOH 46  446 59  HOH HOH A . 
G 5 HOH 47  447 17  HOH HOH A . 
G 5 HOH 48  448 229 HOH HOH A . 
G 5 HOH 49  449 310 HOH HOH A . 
G 5 HOH 50  450 20  HOH HOH A . 
G 5 HOH 51  451 27  HOH HOH A . 
G 5 HOH 52  452 126 HOH HOH A . 
G 5 HOH 53  453 28  HOH HOH A . 
G 5 HOH 54  454 47  HOH HOH A . 
G 5 HOH 55  455 68  HOH HOH A . 
G 5 HOH 56  456 34  HOH HOH A . 
G 5 HOH 57  457 134 HOH HOH A . 
G 5 HOH 58  458 65  HOH HOH A . 
G 5 HOH 59  459 8   HOH HOH A . 
G 5 HOH 60  460 232 HOH HOH A . 
G 5 HOH 61  461 72  HOH HOH A . 
G 5 HOH 62  462 26  HOH HOH A . 
G 5 HOH 63  463 35  HOH HOH A . 
G 5 HOH 64  464 142 HOH HOH A . 
G 5 HOH 65  465 40  HOH HOH A . 
G 5 HOH 66  466 38  HOH HOH A . 
G 5 HOH 67  467 29  HOH HOH A . 
G 5 HOH 68  468 71  HOH HOH A . 
G 5 HOH 69  469 55  HOH HOH A . 
G 5 HOH 70  470 83  HOH HOH A . 
G 5 HOH 71  471 48  HOH HOH A . 
G 5 HOH 72  472 260 HOH HOH A . 
G 5 HOH 73  473 46  HOH HOH A . 
G 5 HOH 74  474 39  HOH HOH A . 
G 5 HOH 75  475 58  HOH HOH A . 
G 5 HOH 76  476 96  HOH HOH A . 
G 5 HOH 77  477 301 HOH HOH A . 
G 5 HOH 78  478 309 HOH HOH A . 
G 5 HOH 79  479 317 HOH HOH A . 
G 5 HOH 80  480 56  HOH HOH A . 
G 5 HOH 81  481 246 HOH HOH A . 
G 5 HOH 82  482 74  HOH HOH A . 
G 5 HOH 83  483 63  HOH HOH A . 
G 5 HOH 84  484 52  HOH HOH A . 
G 5 HOH 85  485 50  HOH HOH A . 
G 5 HOH 86  486 272 HOH HOH A . 
G 5 HOH 87  487 112 HOH HOH A . 
G 5 HOH 88  488 92  HOH HOH A . 
G 5 HOH 89  489 219 HOH HOH A . 
G 5 HOH 90  490 73  HOH HOH A . 
G 5 HOH 91  491 89  HOH HOH A . 
G 5 HOH 92  492 82  HOH HOH A . 
G 5 HOH 93  493 53  HOH HOH A . 
G 5 HOH 94  494 321 HOH HOH A . 
G 5 HOH 95  495 51  HOH HOH A . 
G 5 HOH 96  496 123 HOH HOH A . 
G 5 HOH 97  497 81  HOH HOH A . 
G 5 HOH 98  498 62  HOH HOH A . 
G 5 HOH 99  499 106 HOH HOH A . 
G 5 HOH 100 500 13  HOH HOH A . 
G 5 HOH 101 501 77  HOH HOH A . 
G 5 HOH 102 502 23  HOH HOH A . 
G 5 HOH 103 503 76  HOH HOH A . 
G 5 HOH 104 504 95  HOH HOH A . 
G 5 HOH 105 505 110 HOH HOH A . 
G 5 HOH 106 506 80  HOH HOH A . 
G 5 HOH 107 507 75  HOH HOH A . 
G 5 HOH 108 508 297 HOH HOH A . 
G 5 HOH 109 509 155 HOH HOH A . 
G 5 HOH 110 510 162 HOH HOH A . 
G 5 HOH 111 511 114 HOH HOH A . 
G 5 HOH 112 512 90  HOH HOH A . 
G 5 HOH 113 513 88  HOH HOH A . 
G 5 HOH 114 514 154 HOH HOH A . 
G 5 HOH 115 515 87  HOH HOH A . 
G 5 HOH 116 516 43  HOH HOH A . 
G 5 HOH 117 517 99  HOH HOH A . 
G 5 HOH 118 518 291 HOH HOH A . 
G 5 HOH 119 519 133 HOH HOH A . 
G 5 HOH 120 520 115 HOH HOH A . 
G 5 HOH 121 521 249 HOH HOH A . 
G 5 HOH 122 522 107 HOH HOH A . 
G 5 HOH 123 523 124 HOH HOH A . 
G 5 HOH 124 524 276 HOH HOH A . 
G 5 HOH 125 525 86  HOH HOH A . 
G 5 HOH 126 526 84  HOH HOH A . 
G 5 HOH 127 527 79  HOH HOH A . 
G 5 HOH 128 528 109 HOH HOH A . 
G 5 HOH 129 529 117 HOH HOH A . 
G 5 HOH 130 530 152 HOH HOH A . 
G 5 HOH 131 531 15  HOH HOH A . 
G 5 HOH 132 532 113 HOH HOH A . 
G 5 HOH 133 533 140 HOH HOH A . 
G 5 HOH 134 534 105 HOH HOH A . 
G 5 HOH 135 535 98  HOH HOH A . 
G 5 HOH 136 536 132 HOH HOH A . 
G 5 HOH 137 537 103 HOH HOH A . 
G 5 HOH 138 538 61  HOH HOH A . 
G 5 HOH 139 539 116 HOH HOH A . 
G 5 HOH 140 540 322 HOH HOH A . 
G 5 HOH 141 541 6   HOH HOH A . 
G 5 HOH 142 542 64  HOH HOH A . 
G 5 HOH 143 543 3   HOH HOH A . 
G 5 HOH 144 544 102 HOH HOH A . 
G 5 HOH 145 545 127 HOH HOH A . 
G 5 HOH 146 546 151 HOH HOH A . 
G 5 HOH 147 547 100 HOH HOH A . 
G 5 HOH 148 548 85  HOH HOH A . 
G 5 HOH 149 549 149 HOH HOH A . 
G 5 HOH 150 550 41  HOH HOH A . 
G 5 HOH 151 551 101 HOH HOH A . 
G 5 HOH 152 552 158 HOH HOH A . 
G 5 HOH 153 553 302 HOH HOH A . 
G 5 HOH 154 554 225 HOH HOH A . 
G 5 HOH 155 555 165 HOH HOH A . 
G 5 HOH 156 556 298 HOH HOH A . 
G 5 HOH 157 557 131 HOH HOH A . 
G 5 HOH 158 558 136 HOH HOH A . 
G 5 HOH 159 559 250 HOH HOH A . 
G 5 HOH 160 560 247 HOH HOH A . 
G 5 HOH 161 561 148 HOH HOH A . 
G 5 HOH 162 562 147 HOH HOH A . 
G 5 HOH 163 563 145 HOH HOH A . 
G 5 HOH 164 564 139 HOH HOH A . 
G 5 HOH 165 565 91  HOH HOH A . 
G 5 HOH 166 566 199 HOH HOH A . 
G 5 HOH 167 567 104 HOH HOH A . 
G 5 HOH 168 568 169 HOH HOH A . 
G 5 HOH 169 569 326 HOH HOH A . 
G 5 HOH 170 570 129 HOH HOH A . 
G 5 HOH 171 571 137 HOH HOH A . 
G 5 HOH 172 572 168 HOH HOH A . 
G 5 HOH 173 573 144 HOH HOH A . 
G 5 HOH 174 574 141 HOH HOH A . 
G 5 HOH 175 575 118 HOH HOH A . 
G 5 HOH 176 576 159 HOH HOH A . 
G 5 HOH 177 577 305 HOH HOH A . 
G 5 HOH 178 578 316 HOH HOH A . 
G 5 HOH 179 579 270 HOH HOH A . 
G 5 HOH 180 580 164 HOH HOH A . 
G 5 HOH 181 581 273 HOH HOH A . 
G 5 HOH 182 582 122 HOH HOH A . 
G 5 HOH 183 583 130 HOH HOH A . 
G 5 HOH 184 584 311 HOH HOH A . 
G 5 HOH 185 585 253 HOH HOH A . 
G 5 HOH 186 586 227 HOH HOH A . 
G 5 HOH 187 587 163 HOH HOH A . 
G 5 HOH 188 588 138 HOH HOH A . 
G 5 HOH 189 589 166 HOH HOH A . 
G 5 HOH 190 590 135 HOH HOH A . 
G 5 HOH 191 591 171 HOH HOH A . 
G 5 HOH 192 592 161 HOH HOH A . 
G 5 HOH 193 593 252 HOH HOH A . 
G 5 HOH 194 594 267 HOH HOH A . 
G 5 HOH 195 595 153 HOH HOH A . 
G 5 HOH 196 596 238 HOH HOH A . 
G 5 HOH 197 597 170 HOH HOH A . 
G 5 HOH 198 598 121 HOH HOH A . 
G 5 HOH 199 599 160 HOH HOH A . 
G 5 HOH 200 600 175 HOH HOH A . 
G 5 HOH 201 601 236 HOH HOH A . 
G 5 HOH 202 602 279 HOH HOH A . 
G 5 HOH 203 603 157 HOH HOH A . 
G 5 HOH 204 604 304 HOH HOH A . 
G 5 HOH 205 605 242 HOH HOH A . 
G 5 HOH 206 606 245 HOH HOH A . 
G 5 HOH 207 607 231 HOH HOH A . 
G 5 HOH 208 608 264 HOH HOH A . 
G 5 HOH 209 609 268 HOH HOH A . 
G 5 HOH 210 610 274 HOH HOH A . 
G 5 HOH 211 611 167 HOH HOH A . 
G 5 HOH 212 612 176 HOH HOH A . 
G 5 HOH 213 613 315 HOH HOH A . 
G 5 HOH 214 614 295 HOH HOH A . 
G 5 HOH 215 615 172 HOH HOH A . 
G 5 HOH 216 616 57  HOH HOH A . 
G 5 HOH 217 617 143 HOH HOH A . 
G 5 HOH 218 618 277 HOH HOH A . 
G 5 HOH 219 619 174 HOH HOH A . 
G 5 HOH 220 620 173 HOH HOH A . 
G 5 HOH 221 621 258 HOH HOH A . 
G 5 HOH 222 622 182 HOH HOH A . 
G 5 HOH 223 623 248 HOH HOH A . 
G 5 HOH 224 624 294 HOH HOH A . 
G 5 HOH 225 625 257 HOH HOH A . 
G 5 HOH 226 626 319 HOH HOH A . 
G 5 HOH 227 627 226 HOH HOH A . 
G 5 HOH 228 628 181 HOH HOH A . 
G 5 HOH 229 629 177 HOH HOH A . 
G 5 HOH 230 630 285 HOH HOH A . 
G 5 HOH 231 631 312 HOH HOH A . 
G 5 HOH 232 632 293 HOH HOH A . 
G 5 HOH 233 633 324 HOH HOH A . 
G 5 HOH 234 634 180 HOH HOH A . 
G 5 HOH 235 635 179 HOH HOH A . 
G 5 HOH 236 636 299 HOH HOH A . 
G 5 HOH 237 637 269 HOH HOH A . 
G 5 HOH 238 638 183 HOH HOH A . 
G 5 HOH 239 639 187 HOH HOH A . 
G 5 HOH 240 640 239 HOH HOH A . 
G 5 HOH 241 641 193 HOH HOH A . 
G 5 HOH 242 642 178 HOH HOH A . 
G 5 HOH 243 643 125 HOH HOH A . 
G 5 HOH 244 644 185 HOH HOH A . 
G 5 HOH 245 645 288 HOH HOH A . 
G 5 HOH 246 646 224 HOH HOH A . 
G 5 HOH 247 647 186 HOH HOH A . 
G 5 HOH 248 648 195 HOH HOH A . 
G 5 HOH 249 649 191 HOH HOH A . 
G 5 HOH 250 650 241 HOH HOH A . 
G 5 HOH 251 651 188 HOH HOH A . 
G 5 HOH 252 652 283 HOH HOH A . 
G 5 HOH 253 653 265 HOH HOH A . 
G 5 HOH 254 654 202 HOH HOH A . 
G 5 HOH 255 655 189 HOH HOH A . 
G 5 HOH 256 656 233 HOH HOH A . 
G 5 HOH 257 657 196 HOH HOH A . 
G 5 HOH 258 658 244 HOH HOH A . 
G 5 HOH 259 659 194 HOH HOH A . 
G 5 HOH 260 660 204 HOH HOH A . 
G 5 HOH 261 661 192 HOH HOH A . 
G 5 HOH 262 662 303 HOH HOH A . 
G 5 HOH 263 663 198 HOH HOH A . 
G 5 HOH 264 664 282 HOH HOH A . 
G 5 HOH 265 665 200 HOH HOH A . 
G 5 HOH 266 666 228 HOH HOH A . 
G 5 HOH 267 667 120 HOH HOH A . 
G 5 HOH 268 668 201 HOH HOH A . 
G 5 HOH 269 669 212 HOH HOH A . 
G 5 HOH 270 670 207 HOH HOH A . 
G 5 HOH 271 671 240 HOH HOH A . 
G 5 HOH 272 672 197 HOH HOH A . 
G 5 HOH 273 673 275 HOH HOH A . 
G 5 HOH 274 674 307 HOH HOH A . 
G 5 HOH 275 675 205 HOH HOH A . 
G 5 HOH 276 676 320 HOH HOH A . 
G 5 HOH 277 677 206 HOH HOH A . 
G 5 HOH 278 678 209 HOH HOH A . 
G 5 HOH 279 679 32  HOH HOH A . 
G 5 HOH 280 680 254 HOH HOH A . 
G 5 HOH 281 681 286 HOH HOH A . 
G 5 HOH 282 682 208 HOH HOH A . 
G 5 HOH 283 683 203 HOH HOH A . 
G 5 HOH 284 684 280 HOH HOH A . 
G 5 HOH 285 685 211 HOH HOH A . 
G 5 HOH 286 686 210 HOH HOH A . 
G 5 HOH 287 687 328 HOH HOH A . 
G 5 HOH 288 688 213 HOH HOH A . 
G 5 HOH 289 689 251 HOH HOH A . 
G 5 HOH 290 690 214 HOH HOH A . 
G 5 HOH 291 691 278 HOH HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 0 A TRP 165 ? N   A A TRP 161 N   
2  1 Y 0 A TRP 165 ? CA  A A TRP 161 CA  
3  1 Y 0 A TRP 165 ? C   A A TRP 161 C   
4  1 Y 0 A TRP 165 ? O   A A TRP 161 O   
5  1 Y 0 A TRP 165 ? CB  A A TRP 161 CB  
6  1 Y 0 A TRP 165 ? CG  A A TRP 161 CG  
7  1 Y 0 A TRP 165 ? CD1 A A TRP 161 CD1 
8  1 Y 0 A TRP 165 ? CD2 A A TRP 161 CD2 
9  1 Y 0 A TRP 165 ? NE1 A A TRP 161 NE1 
10 1 Y 0 A TRP 165 ? CE2 A A TRP 161 CE2 
11 1 Y 0 A TRP 165 ? CE3 A A TRP 161 CE3 
12 1 Y 0 A TRP 165 ? CZ2 A A TRP 161 CZ2 
13 1 Y 0 A TRP 165 ? CZ3 A A TRP 161 CZ3 
14 1 Y 0 A TRP 165 ? CH2 A A TRP 161 CH2 
15 1 Y 0 A GLN 166 ? N   A A GLN 162 N   
16 1 Y 0 A GLN 166 ? CA  A A GLN 162 CA  
17 1 Y 0 A GLN 166 ? C   A A GLN 162 C   
18 1 Y 0 A GLN 166 ? O   A A GLN 162 O   
19 1 Y 0 A GLN 166 ? CB  A A GLN 162 CB  
20 1 Y 0 A GLN 166 ? CG  A A GLN 162 CG  
21 1 Y 0 A GLN 166 ? CD  A A GLN 162 CD  
22 1 Y 0 A GLN 166 ? OE1 A A GLN 162 OE1 
23 1 Y 0 A GLN 166 ? NE2 A A GLN 162 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8RWS 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     60.117 
_cell.length_a_esd                 ? 
_cell.length_b                     78.753 
_cell.length_b_esd                 ? 
_cell.length_c                     56.155 
_cell.length_c_esd                 ? 
_cell.volume                       265859.901 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8RWS 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                18 
_symmetry.space_group_name_Hall            'P 2 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8RWS 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.15 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          42.88 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2 M Ammonium Sulphate, 5 % Ethanol' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-10-12 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.81531 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.81531 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          13.45 
_reflns.entry_id                                       8RWS 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.09 
_reflns.d_resolution_low                               36.39 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     110930 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.4 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.042 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.09 
_reflns_shell.d_res_low                                     1.11 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.3 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             5376 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               1.105 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.324 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               20.28 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8RWS 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.09 
_refine.ls_d_res_low                             36.39 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     110309 
_refine.ls_number_reflns_R_free                  5441 
_refine.ls_number_reflns_R_work                  104868 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.81 
_refine.ls_percent_reflns_R_free                 4.93 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1753 
_refine.ls_R_factor_R_free                       0.1996 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1740 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 27.0043 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2048 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.09 
_refine_hist.d_res_low                        36.39 
_refine_hist.number_atoms_solvent             291 
_refine_hist.number_atoms_total               2352 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1994 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         67 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0071  ? 2333 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0188  ? 3215 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0750  ? 351  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0130  ? 426  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.3670 ? 868  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.09 1.10  . . 160 3049 86.94  . . . . 0.4692 . . . . . . . . . . . 0.4958 
'X-RAY DIFFRACTION' 1.10 1.12  . . 152 3340 95.46  . . . . 0.4569 . . . . . . . . . . . 0.4346 
'X-RAY DIFFRACTION' 1.12 1.13  . . 176 3420 97.72  . . . . 0.4414 . . . . . . . . . . . 0.4436 
'X-RAY DIFFRACTION' 1.13 1.14  . . 209 3431 98.38  . . . . 0.4245 . . . . . . . . . . . 0.4340 
'X-RAY DIFFRACTION' 1.14 1.16  . . 181 3423 98.15  . . . . 0.4013 . . . . . . . . . . . 0.4358 
'X-RAY DIFFRACTION' 1.16 1.17  . . 179 3474 98.84  . . . . 0.3851 . . . . . . . . . . . 0.3836 
'X-RAY DIFFRACTION' 1.17 1.19  . . 188 3448 99.02  . . . . 0.3743 . . . . . . . . . . . 0.3930 
'X-RAY DIFFRACTION' 1.19 1.21  . . 197 3455 98.54  . . . . 0.3554 . . . . . . . . . . . 0.3561 
'X-RAY DIFFRACTION' 1.21 1.23  . . 176 3452 98.59  . . . . 0.3354 . . . . . . . . . . . 0.3152 
'X-RAY DIFFRACTION' 1.23 1.25  . . 208 3462 99.35  . . . . 0.3257 . . . . . . . . . . . 0.3785 
'X-RAY DIFFRACTION' 1.25 1.27  . . 170 3465 99.21  . . . . 0.3091 . . . . . . . . . . . 0.3150 
'X-RAY DIFFRACTION' 1.27 1.29  . . 159 3477 98.97  . . . . 0.2811 . . . . . . . . . . . 0.2917 
'X-RAY DIFFRACTION' 1.29 1.32  . . 173 3495 99.14  . . . . 0.2684 . . . . . . . . . . . 0.3120 
'X-RAY DIFFRACTION' 1.32 1.34  . . 160 3518 99.19  . . . . 0.2511 . . . . . . . . . . . 0.2820 
'X-RAY DIFFRACTION' 1.34 1.37  . . 166 3514 99.27  . . . . 0.2394 . . . . . . . . . . . 0.2462 
'X-RAY DIFFRACTION' 1.37 1.41  . . 176 3500 99.49  . . . . 0.2264 . . . . . . . . . . . 0.2594 
'X-RAY DIFFRACTION' 1.41 1.44  . . 161 3538 99.60  . . . . 0.1945 . . . . . . . . . . . 0.2476 
'X-RAY DIFFRACTION' 1.44 1.48  . . 198 3499 99.65  . . . . 0.1817 . . . . . . . . . . . 0.2118 
'X-RAY DIFFRACTION' 1.48 1.52  . . 181 3500 99.68  . . . . 0.1634 . . . . . . . . . . . 0.1838 
'X-RAY DIFFRACTION' 1.52 1.57  . . 207 3502 99.81  . . . . 0.1540 . . . . . . . . . . . 0.1976 
'X-RAY DIFFRACTION' 1.57 1.63  . . 217 3491 99.76  . . . . 0.1435 . . . . . . . . . . . 0.1851 
'X-RAY DIFFRACTION' 1.63 1.69  . . 161 3534 99.86  . . . . 0.1384 . . . . . . . . . . . 0.1826 
'X-RAY DIFFRACTION' 1.69 1.77  . . 185 3555 99.92  . . . . 0.1430 . . . . . . . . . . . 0.2028 
'X-RAY DIFFRACTION' 1.77 1.86  . . 183 3555 99.97  . . . . 0.1357 . . . . . . . . . . . 0.1841 
'X-RAY DIFFRACTION' 1.86 1.98  . . 191 3538 100.00 . . . . 0.1249 . . . . . . . . . . . 0.1746 
'X-RAY DIFFRACTION' 1.98 2.13  . . 200 3562 99.89  . . . . 0.1220 . . . . . . . . . . . 0.1440 
'X-RAY DIFFRACTION' 2.13 2.35  . . 198 3564 99.81  . . . . 0.1188 . . . . . . . . . . . 0.1453 
'X-RAY DIFFRACTION' 2.35 2.69  . . 168 3625 99.97  . . . . 0.1233 . . . . . . . . . . . 0.1385 
'X-RAY DIFFRACTION' 2.69 3.39  . . 176 3657 100.00 . . . . 0.1375 . . . . . . . . . . . 0.1578 
'X-RAY DIFFRACTION' 3.39 36.39 . . 185 3825 99.95  . . . . 0.1512 . . . . . . . . . . . 0.1717 
# 
_struct.entry_id                     8RWS 
_struct.title                        'KPC-2 G89D/E166Q Mutant in Complex with Meropenem' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8RWS 
_struct_keywords.text            'Beta-Lactamase, Carbapenem, Antibiotic Resistance, ANTIMICROBIAL PROTEIN' 
_struct_keywords.pdbx_keywords   'ANTIMICROBIAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 2 ? 
G N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    BLKPC_KLEPN 
_struct_ref.pdbx_db_accession          Q9F663 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;LTNLVAEPFAKLEQDFGGSIGVYAMDTGSGATVSYRAEERFPLCSSFKGFLAAAVLARSQQQAGLLDTPIRYGKNALVPW
SPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGPAGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRA
VTESLQKLTLGSALAAPQRQQFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGVYGTANDYAVVWPTGRAPIVLAVYTR
APNKDDKHSEAVIAAAARLALEGLGVNGQ
;
_struct_ref.pdbx_align_begin           0 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8RWS 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 22 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 290 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q9F663 
_struct_ref_seq.db_align_beg                  25 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  293 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       25 
_struct_ref_seq.pdbx_auth_seq_align_end       295 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8RWS MET A 1   ? UNP Q9F663 ?   ?   'initiating methionine' 4   1  
1 8RWS GLY A 2   ? UNP Q9F663 ?   ?   'expression tag'        5   2  
1 8RWS SER A 3   ? UNP Q9F663 ?   ?   'expression tag'        6   3  
1 8RWS SER A 4   ? UNP Q9F663 ?   ?   'expression tag'        7   4  
1 8RWS HIS A 5   ? UNP Q9F663 ?   ?   'expression tag'        8   5  
1 8RWS HIS A 6   ? UNP Q9F663 ?   ?   'expression tag'        9   6  
1 8RWS HIS A 7   ? UNP Q9F663 ?   ?   'expression tag'        10  7  
1 8RWS HIS A 8   ? UNP Q9F663 ?   ?   'expression tag'        11  8  
1 8RWS HIS A 9   ? UNP Q9F663 ?   ?   'expression tag'        12  9  
1 8RWS HIS A 10  ? UNP Q9F663 ?   ?   'expression tag'        13  10 
1 8RWS SER A 11  ? UNP Q9F663 ?   ?   'expression tag'        14  11 
1 8RWS SER A 12  ? UNP Q9F663 ?   ?   'expression tag'        15  12 
1 8RWS GLY A 13  ? UNP Q9F663 ?   ?   'expression tag'        16  13 
1 8RWS LEU A 14  ? UNP Q9F663 ?   ?   'expression tag'        17  14 
1 8RWS VAL A 15  ? UNP Q9F663 ?   ?   'expression tag'        18  15 
1 8RWS PRO A 16  ? UNP Q9F663 ?   ?   'expression tag'        19  16 
1 8RWS ARG A 17  ? UNP Q9F663 ?   ?   'expression tag'        20  17 
1 8RWS GLY A 18  ? UNP Q9F663 ?   ?   'expression tag'        21  18 
1 8RWS SER A 19  ? UNP Q9F663 ?   ?   'expression tag'        22  19 
1 8RWS HIS A 20  ? UNP Q9F663 ?   ?   'expression tag'        23  20 
1 8RWS MET A 21  ? UNP Q9F663 ?   ?   'expression tag'        24  21 
1 8RWS ASP A 85  ? UNP Q9F663 GLY 88  'engineered mutation'   89  22 
1 8RWS GLN A 162 ? UNP Q9F663 GLU 165 'engineered mutation'   166 23 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 870   ? 
1 MORE         -22   ? 
1 'SSA (A^2)'  11020 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 26  ? GLY A 38  ? VAL A 29  GLY A 41  1 ? 13 
HELX_P HELX_P2  AA2 SER A 67  ? GLN A 83  ? SER A 71  GLN A 87  1 ? 17 
HELX_P HELX_P3  AA3 GLY A 94  ? LEU A 98  ? GLY A 98  LEU A 102 5 ? 5  
HELX_P HELX_P4  AA4 ILE A 104 ? LEU A 109 ? ILE A 108 LEU A 113 5 ? 6  
HELX_P HELX_P5  AA5 VAL A 115 ? TYR A 125 ? VAL A 119 TYR A 129 1 ? 11 
HELX_P HELX_P6  AA6 ASP A 127 ? LEU A 138 ? ASP A 131 LEU A 142 1 ? 12 
HELX_P HELX_P7  AA7 GLY A 139 ? ILE A 151 ? GLY A 143 ILE A 155 1 ? 13 
HELX_P HELX_P8  AA8 LEU A 163 ? SER A 167 ? LEU A 167 SER A 171 5 ? 5  
HELX_P HELX_P9  AA9 SER A 178 ? LEU A 191 ? SER A 182 LEU A 195 1 ? 14 
HELX_P HELX_P10 AB1 ALA A 196 ? GLY A 209 ? ALA A 200 GLY A 213 1 ? 14 
HELX_P HELX_P11 AB2 ARG A 216 ? VAL A 221 ? ARG A 220 VAL A 225 5 ? 6  
HELX_P HELX_P12 AB3 SER A 270 ? GLY A 286 ? SER A 275 GLY A 291 1 ? 17 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 65 SG ? ? ? 1_555 A CYS 234 SG  ? ? A CYS 69 A CYS 238 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
covale1 covale none ? A SER 66 OG ? ? ? 1_555 D O2F .   C12 A ? A SER 70 A O2F 303 1_555 ? ? ? ? ? ? ? 1.375 ? ? 
covale2 covale none ? A SER 66 OG ? ? ? 1_555 E MER .   C1  B ? A SER 70 A MER 304 1_555 ? ? ? ? ? ? ? 1.371 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 O2F D .  A SER A 66  ? O2F A 303 ? 1_555 SER A 70  ? 1_555 C12 OG SER 1 O2F None 'Covalent chemical modification' 
2 MER E .  B SER A 66  ? MER A 304 ? 1_555 SER A 70  ? 1_555 C1  OG SER 1 MER None 'Covalent chemical modification' 
3 CYS A 65 ? CYS A 234 ? CYS A 69  ? 1_555 CYS A 238 ? 1_555 SG  SG .   . .   None 'Disulfide bridge'               
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 162 A . ? GLN 166 A LEU 163 A ? LEU 167 A 1 9.16   
2 GLN 162 A . ? GLN 166 A LEU 163 A ? LEU 167 A 1 -17.37 
3 GLN 162 A . ? GLN 166 A LEU 163 A ? LEU 167 A 1 13.04  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 53  ? TYR A 56  ? THR A 56  TYR A 60  
AA1 2 SER A 40  ? ASP A 47  ? SER A 43  ASP A 50  
AA1 3 ILE A 254 ? ARG A 261 ? ILE A 259 ARG A 266 
AA1 4 ALA A 240 ? TRP A 247 ? ALA A 244 TRP A 251 
AA1 5 ALA A 226 ? THR A 233 ? ALA A 230 THR A 237 
AA2 1 PHE A 62  ? PRO A 63  ? PHE A 66  PRO A 67  
AA2 2 THR A 176 ? SER A 177 ? THR A 180 SER A 181 
AA3 1 PRO A 90  ? ILE A 91  ? PRO A 94  ILE A 95  
AA3 2 MET A 113 ? THR A 114 ? MET A 117 THR A 118 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O TYR A 56  ? O TYR A 60  N VAL A 43  ? N VAL A 46  
AA1 2 3 N MET A 46  ? N MET A 49  O VAL A 255 ? O VAL A 260 
AA1 3 4 O ILE A 254 ? O ILE A 259 N VAL A 246 ? N VAL A 250 
AA1 4 5 O TRP A 247 ? O TRP A 251 N ALA A 226 ? N ALA A 230 
AA2 1 2 N PHE A 62  ? N PHE A 66  O SER A 177 ? O SER A 181 
AA3 1 2 N ILE A 91  ? N ILE A 95  O MET A 113 ? O MET A 117 
# 
_pdbx_entry_details.entry_id                   8RWS 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OD1 A ASP 92  ? ? O  A HOH 401 ? ? 1.92 
2  1 O   A HOH 431 ? ? O  A HOH 645 ? ? 2.08 
3  1 O   A HOH 638 ? ? O  A HOH 658 ? ? 2.11 
4  1 O   A HOH 414 ? ? O  A HOH 416 ? ? 2.12 
5  1 O   A HOH 441 ? ? O  A HOH 533 ? ? 2.15 
6  1 O   A HOH 464 ? ? O  A HOH 577 ? ? 2.16 
7  1 O   A HOH 485 ? ? O  A HOH 625 ? ? 2.17 
8  1 OG  A SER 70  ? ? O3 A O2F 303 ? A 2.17 
9  1 O   A HOH 614 ? ? O  A HOH 632 ? ? 2.18 
10 1 O   A HOH 596 ? ? O  A HOH 665 ? ? 2.18 
11 1 O   A HOH 420 ? ? O  A HOH 580 ? ? 2.19 
12 1 O   A HOH 582 ? ? O  A HOH 630 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 CYS A 69  ? ? 49.36   -141.85 
2 1 TRP A 105 ? ? 61.09   71.56   
3 1 TRP A 105 ? ? 61.41   71.28   
4 1 ARG A 220 ? ? -115.48 -125.19 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     153 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.092 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x+1/2,y+1/2,-z 
4 -x,-y,z         
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 689 ? 6.23 . 
2 1 O ? A HOH 690 ? 6.59 . 
3 1 O ? A HOH 691 ? 7.21 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 4   ? A MET 1   
2  1 Y 1 A GLY 5   ? A GLY 2   
3  1 Y 1 A SER 6   ? A SER 3   
4  1 Y 1 A SER 7   ? A SER 4   
5  1 Y 1 A HIS 8   ? A HIS 5   
6  1 Y 1 A HIS 9   ? A HIS 6   
7  1 Y 1 A HIS 10  ? A HIS 7   
8  1 Y 1 A HIS 11  ? A HIS 8   
9  1 Y 1 A HIS 12  ? A HIS 9   
10 1 Y 1 A HIS 13  ? A HIS 10  
11 1 Y 1 A SER 14  ? A SER 11  
12 1 Y 1 A SER 15  ? A SER 12  
13 1 Y 1 A GLY 16  ? A GLY 13  
14 1 Y 1 A LEU 17  ? A LEU 14  
15 1 Y 1 A VAL 18  ? A VAL 15  
16 1 Y 1 A PRO 19  ? A PRO 16  
17 1 Y 1 A ARG 20  ? A ARG 17  
18 1 Y 1 A GLY 21  ? A GLY 18  
19 1 Y 1 A SER 22  ? A SER 19  
20 1 Y 1 A HIS 23  ? A HIS 20  
21 1 Y 1 A MET 24  ? A MET 21  
22 1 Y 1 A LEU 25  ? A LEU 22  
23 1 Y 1 A GLN 295 ? A GLN 290 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MER C1   C N N 230 
MER C2   C N N 231 
MER C3   C N S 232 
MER C4   C N S 233 
MER C5   C N N 234 
MER O6   O N N 235 
MER C7   C N R 236 
MER O8   O N N 237 
MER C9   C N N 238 
MER N10  N N N 239 
MER C11  C N N 240 
MER O12  O N N 241 
MER O13  O N N 242 
MER S14  S N N 243 
MER C15  C N S 244 
MER C16  C N N 245 
MER C17  C N S 246 
MER C18  C N R 247 
MER N19  N N N 248 
MER C20  C N N 249 
MER C21  C N N 250 
MER C22  C N N 251 
MER N23  N N N 252 
MER O24  O N N 253 
MER C25  C N N 254 
MER C26  C N N 255 
MER H1   H N N 256 
MER H3   H N N 257 
MER H4   H N N 258 
MER H7   H N N 259 
MER HO8  H N N 260 
MER H9   H N N 261 
MER H9A  H N N 262 
MER H9B  H N N 263 
MER HN10 H N N 264 
MER HO12 H N N 265 
MER H15  H N N 266 
MER H16  H N N 267 
MER H16A H N N 268 
MER H17  H N N 269 
MER H18  H N N 270 
MER HN19 H N N 271 
MER H20  H N N 272 
MER H20A H N N 273 
MER H20B H N N 274 
MER H21  H N N 275 
MER H21A H N N 276 
MER H25  H N N 277 
MER H25A H N N 278 
MER H25B H N N 279 
MER H26  H N N 280 
MER H26A H N N 281 
MER H26B H N N 282 
MET N    N N N 283 
MET CA   C N S 284 
MET C    C N N 285 
MET O    O N N 286 
MET CB   C N N 287 
MET CG   C N N 288 
MET SD   S N N 289 
MET CE   C N N 290 
MET OXT  O N N 291 
MET H    H N N 292 
MET H2   H N N 293 
MET HA   H N N 294 
MET HB2  H N N 295 
MET HB3  H N N 296 
MET HG2  H N N 297 
MET HG3  H N N 298 
MET HE1  H N N 299 
MET HE2  H N N 300 
MET HE3  H N N 301 
MET HXT  H N N 302 
O2F C1   C N N 303 
O2F C2   C N N 304 
O2F C3   C N S 305 
O2F C4   C N N 306 
O2F C5   C N N 307 
O2F C7   C N R 308 
O2F C9   C N N 309 
O2F C11  C N S 310 
O2F C15  C N R 311 
O2F C16  C N N 312 
O2F N    N N N 313 
O2F C    C N N 314 
O2F O    O N N 315 
O2F C10  C N S 316 
O2F C12  C N N 317 
O2F C13  C N R 318 
O2F C14  C N N 319 
O2F C6   C N S 320 
O2F C8   C N N 321 
O2F N1   N N N 322 
O2F N2   N N N 323 
O2F O1   O N N 324 
O2F O2   O N N 325 
O2F O3   O N N 326 
O2F O4   O N N 327 
O2F S    S N N 328 
O2F H7   H N N 329 
O2F H8   H N N 330 
O2F H6   H N N 331 
O2F H11  H N N 332 
O2F H9   H N N 333 
O2F H10  H N N 334 
O2F H    H N N 335 
O2F H13  H N N 336 
O2F H14  H N N 337 
O2F H16  H N N 338 
O2F H15  H N N 339 
O2F H2   H N N 340 
O2F H18  H N N 341 
O2F H5   H N N 342 
O2F H25  H N N 343 
O2F H24  H N N 344 
O2F H26  H N N 345 
O2F H3   H N N 346 
O2F H19  H N N 347 
O2F H4   H N N 348 
O2F H20  H N N 349 
O2F H22  H N N 350 
O2F H21  H N N 351 
O2F H1   H N N 352 
O2F H12  H N N 353 
O2F H17  H N N 354 
O2F H23  H N N 355 
PHE N    N N N 356 
PHE CA   C N S 357 
PHE C    C N N 358 
PHE O    O N N 359 
PHE CB   C N N 360 
PHE CG   C Y N 361 
PHE CD1  C Y N 362 
PHE CD2  C Y N 363 
PHE CE1  C Y N 364 
PHE CE2  C Y N 365 
PHE CZ   C Y N 366 
PHE OXT  O N N 367 
PHE H    H N N 368 
PHE H2   H N N 369 
PHE HA   H N N 370 
PHE HB2  H N N 371 
PHE HB3  H N N 372 
PHE HD1  H N N 373 
PHE HD2  H N N 374 
PHE HE1  H N N 375 
PHE HE2  H N N 376 
PHE HZ   H N N 377 
PHE HXT  H N N 378 
PRO N    N N N 379 
PRO CA   C N S 380 
PRO C    C N N 381 
PRO O    O N N 382 
PRO CB   C N N 383 
PRO CG   C N N 384 
PRO CD   C N N 385 
PRO OXT  O N N 386 
PRO H    H N N 387 
PRO HA   H N N 388 
PRO HB2  H N N 389 
PRO HB3  H N N 390 
PRO HG2  H N N 391 
PRO HG3  H N N 392 
PRO HD2  H N N 393 
PRO HD3  H N N 394 
PRO HXT  H N N 395 
SER N    N N N 396 
SER CA   C N S 397 
SER C    C N N 398 
SER O    O N N 399 
SER CB   C N N 400 
SER OG   O N N 401 
SER OXT  O N N 402 
SER H    H N N 403 
SER H2   H N N 404 
SER HA   H N N 405 
SER HB2  H N N 406 
SER HB3  H N N 407 
SER HG   H N N 408 
SER HXT  H N N 409 
SO4 S    S N N 410 
SO4 O1   O N N 411 
SO4 O2   O N N 412 
SO4 O3   O N N 413 
SO4 O4   O N N 414 
THR N    N N N 415 
THR CA   C N S 416 
THR C    C N N 417 
THR O    O N N 418 
THR CB   C N R 419 
THR OG1  O N N 420 
THR CG2  C N N 421 
THR OXT  O N N 422 
THR H    H N N 423 
THR H2   H N N 424 
THR HA   H N N 425 
THR HB   H N N 426 
THR HG1  H N N 427 
THR HG21 H N N 428 
THR HG22 H N N 429 
THR HG23 H N N 430 
THR HXT  H N N 431 
TRP N    N N N 432 
TRP CA   C N S 433 
TRP C    C N N 434 
TRP O    O N N 435 
TRP CB   C N N 436 
TRP CG   C Y N 437 
TRP CD1  C Y N 438 
TRP CD2  C Y N 439 
TRP NE1  N Y N 440 
TRP CE2  C Y N 441 
TRP CE3  C Y N 442 
TRP CZ2  C Y N 443 
TRP CZ3  C Y N 444 
TRP CH2  C Y N 445 
TRP OXT  O N N 446 
TRP H    H N N 447 
TRP H2   H N N 448 
TRP HA   H N N 449 
TRP HB2  H N N 450 
TRP HB3  H N N 451 
TRP HD1  H N N 452 
TRP HE1  H N N 453 
TRP HE3  H N N 454 
TRP HZ2  H N N 455 
TRP HZ3  H N N 456 
TRP HH2  H N N 457 
TRP HXT  H N N 458 
TYR N    N N N 459 
TYR CA   C N S 460 
TYR C    C N N 461 
TYR O    O N N 462 
TYR CB   C N N 463 
TYR CG   C Y N 464 
TYR CD1  C Y N 465 
TYR CD2  C Y N 466 
TYR CE1  C Y N 467 
TYR CE2  C Y N 468 
TYR CZ   C Y N 469 
TYR OH   O N N 470 
TYR OXT  O N N 471 
TYR H    H N N 472 
TYR H2   H N N 473 
TYR HA   H N N 474 
TYR HB2  H N N 475 
TYR HB3  H N N 476 
TYR HD1  H N N 477 
TYR HD2  H N N 478 
TYR HE1  H N N 479 
TYR HE2  H N N 480 
TYR HH   H N N 481 
TYR HXT  H N N 482 
VAL N    N N N 483 
VAL CA   C N S 484 
VAL C    C N N 485 
VAL O    O N N 486 
VAL CB   C N N 487 
VAL CG1  C N N 488 
VAL CG2  C N N 489 
VAL OXT  O N N 490 
VAL H    H N N 491 
VAL H2   H N N 492 
VAL HA   H N N 493 
VAL HB   H N N 494 
VAL HG11 H N N 495 
VAL HG12 H N N 496 
VAL HG13 H N N 497 
VAL HG21 H N N 498 
VAL HG22 H N N 499 
VAL HG23 H N N 500 
VAL HXT  H N N 501 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MER C1  O6   doub N N 218 
MER C1  C3   sing N N 219 
MER C1  H1   sing N N 220 
MER C5  C2   doub N N 221 
MER C2  C18  sing N N 222 
MER C2  S14  sing N N 223 
MER C4  C3   sing N N 224 
MER C3  C7   sing N N 225 
MER C3  H3   sing N N 226 
MER N10 C4   sing N N 227 
MER C4  C18  sing N N 228 
MER C4  H4   sing N N 229 
MER C11 C5   sing N N 230 
MER N10 C5   sing N N 231 
MER O8  C7   sing N N 232 
MER C7  C9   sing N N 233 
MER C7  H7   sing N N 234 
MER O8  HO8  sing N N 235 
MER C9  H9   sing N N 236 
MER C9  H9A  sing N N 237 
MER C9  H9B  sing N N 238 
MER N10 HN10 sing N N 239 
MER O13 C11  doub N N 240 
MER C11 O12  sing N N 241 
MER O12 HO12 sing N N 242 
MER S14 C15  sing N N 243 
MER C16 C15  sing N N 244 
MER C15 C21  sing N N 245 
MER C15 H15  sing N N 246 
MER C16 C17  sing N N 247 
MER C16 H16  sing N N 248 
MER C16 H16A sing N N 249 
MER C22 C17  sing N N 250 
MER C17 N19  sing N N 251 
MER C17 H17  sing N N 252 
MER C18 C20  sing N N 253 
MER C18 H18  sing N N 254 
MER N19 C21  sing N N 255 
MER N19 HN19 sing N N 256 
MER C20 H20  sing N N 257 
MER C20 H20A sing N N 258 
MER C20 H20B sing N N 259 
MER C21 H21  sing N N 260 
MER C21 H21A sing N N 261 
MER N23 C22  sing N N 262 
MER O24 C22  doub N N 263 
MER C25 N23  sing N N 264 
MER N23 C26  sing N N 265 
MER C25 H25  sing N N 266 
MER C25 H25A sing N N 267 
MER C25 H25B sing N N 268 
MER C26 H26  sing N N 269 
MER C26 H26A sing N N 270 
MER C26 H26B sing N N 271 
MET N   CA   sing N N 272 
MET N   H    sing N N 273 
MET N   H2   sing N N 274 
MET CA  C    sing N N 275 
MET CA  CB   sing N N 276 
MET CA  HA   sing N N 277 
MET C   O    doub N N 278 
MET C   OXT  sing N N 279 
MET CB  CG   sing N N 280 
MET CB  HB2  sing N N 281 
MET CB  HB3  sing N N 282 
MET CG  SD   sing N N 283 
MET CG  HG2  sing N N 284 
MET CG  HG3  sing N N 285 
MET SD  CE   sing N N 286 
MET CE  HE1  sing N N 287 
MET CE  HE2  sing N N 288 
MET CE  HE3  sing N N 289 
MET OXT HXT  sing N N 290 
O2F C4  N1   sing N N 291 
O2F C4  C6   sing N N 292 
O2F N1  C3   sing N N 293 
O2F O2  C9   doub N N 294 
O2F C6  S    sing N N 295 
O2F C6  C5   sing N N 296 
O2F O1  C9   sing N N 297 
O2F C9  C8   sing N N 298 
O2F O3  C12  doub N N 299 
O2F C1  N    sing N N 300 
O2F C3  C5   sing N N 301 
O2F C3  C    sing N N 302 
O2F S   C7   sing N N 303 
O2F C8  C7   sing N N 304 
O2F C8  N2   doub N N 305 
O2F C   N    sing N N 306 
O2F C   O    doub N N 307 
O2F C12 C11  sing N N 308 
O2F N   C2   sing N N 309 
O2F C7  C15  sing N N 310 
O2F N2  C10  sing N N 311 
O2F C11 C10  sing N N 312 
O2F C11 C13  sing N N 313 
O2F C10 C15  sing N N 314 
O2F C14 C13  sing N N 315 
O2F C15 C16  sing N N 316 
O2F C13 O4   sing N N 317 
O2F C1  H7   sing N N 318 
O2F C1  H8   sing N N 319 
O2F C1  H6   sing N N 320 
O2F C2  H11  sing N N 321 
O2F C2  H9   sing N N 322 
O2F C2  H10  sing N N 323 
O2F C3  H    sing N N 324 
O2F C4  H13  sing N N 325 
O2F C4  H14  sing N N 326 
O2F C5  H16  sing N N 327 
O2F C5  H15  sing N N 328 
O2F C7  H2   sing N N 329 
O2F C11 H18  sing N N 330 
O2F C15 H5   sing N N 331 
O2F C16 H25  sing N N 332 
O2F C16 H24  sing N N 333 
O2F C16 H26  sing N N 334 
O2F C10 H3   sing N N 335 
O2F C12 H19  sing N N 336 
O2F C13 H4   sing N N 337 
O2F C14 H20  sing N N 338 
O2F C14 H22  sing N N 339 
O2F C14 H21  sing N N 340 
O2F C6  H1   sing N N 341 
O2F N1  H12  sing N N 342 
O2F O1  H17  sing N N 343 
O2F O4  H23  sing N N 344 
PHE N   CA   sing N N 345 
PHE N   H    sing N N 346 
PHE N   H2   sing N N 347 
PHE CA  C    sing N N 348 
PHE CA  CB   sing N N 349 
PHE CA  HA   sing N N 350 
PHE C   O    doub N N 351 
PHE C   OXT  sing N N 352 
PHE CB  CG   sing N N 353 
PHE CB  HB2  sing N N 354 
PHE CB  HB3  sing N N 355 
PHE CG  CD1  doub Y N 356 
PHE CG  CD2  sing Y N 357 
PHE CD1 CE1  sing Y N 358 
PHE CD1 HD1  sing N N 359 
PHE CD2 CE2  doub Y N 360 
PHE CD2 HD2  sing N N 361 
PHE CE1 CZ   doub Y N 362 
PHE CE1 HE1  sing N N 363 
PHE CE2 CZ   sing Y N 364 
PHE CE2 HE2  sing N N 365 
PHE CZ  HZ   sing N N 366 
PHE OXT HXT  sing N N 367 
PRO N   CA   sing N N 368 
PRO N   CD   sing N N 369 
PRO N   H    sing N N 370 
PRO CA  C    sing N N 371 
PRO CA  CB   sing N N 372 
PRO CA  HA   sing N N 373 
PRO C   O    doub N N 374 
PRO C   OXT  sing N N 375 
PRO CB  CG   sing N N 376 
PRO CB  HB2  sing N N 377 
PRO CB  HB3  sing N N 378 
PRO CG  CD   sing N N 379 
PRO CG  HG2  sing N N 380 
PRO CG  HG3  sing N N 381 
PRO CD  HD2  sing N N 382 
PRO CD  HD3  sing N N 383 
PRO OXT HXT  sing N N 384 
SER N   CA   sing N N 385 
SER N   H    sing N N 386 
SER N   H2   sing N N 387 
SER CA  C    sing N N 388 
SER CA  CB   sing N N 389 
SER CA  HA   sing N N 390 
SER C   O    doub N N 391 
SER C   OXT  sing N N 392 
SER CB  OG   sing N N 393 
SER CB  HB2  sing N N 394 
SER CB  HB3  sing N N 395 
SER OG  HG   sing N N 396 
SER OXT HXT  sing N N 397 
SO4 S   O1   doub N N 398 
SO4 S   O2   doub N N 399 
SO4 S   O3   sing N N 400 
SO4 S   O4   sing N N 401 
THR N   CA   sing N N 402 
THR N   H    sing N N 403 
THR N   H2   sing N N 404 
THR CA  C    sing N N 405 
THR CA  CB   sing N N 406 
THR CA  HA   sing N N 407 
THR C   O    doub N N 408 
THR C   OXT  sing N N 409 
THR CB  OG1  sing N N 410 
THR CB  CG2  sing N N 411 
THR CB  HB   sing N N 412 
THR OG1 HG1  sing N N 413 
THR CG2 HG21 sing N N 414 
THR CG2 HG22 sing N N 415 
THR CG2 HG23 sing N N 416 
THR OXT HXT  sing N N 417 
TRP N   CA   sing N N 418 
TRP N   H    sing N N 419 
TRP N   H2   sing N N 420 
TRP CA  C    sing N N 421 
TRP CA  CB   sing N N 422 
TRP CA  HA   sing N N 423 
TRP C   O    doub N N 424 
TRP C   OXT  sing N N 425 
TRP CB  CG   sing N N 426 
TRP CB  HB2  sing N N 427 
TRP CB  HB3  sing N N 428 
TRP CG  CD1  doub Y N 429 
TRP CG  CD2  sing Y N 430 
TRP CD1 NE1  sing Y N 431 
TRP CD1 HD1  sing N N 432 
TRP CD2 CE2  doub Y N 433 
TRP CD2 CE3  sing Y N 434 
TRP NE1 CE2  sing Y N 435 
TRP NE1 HE1  sing N N 436 
TRP CE2 CZ2  sing Y N 437 
TRP CE3 CZ3  doub Y N 438 
TRP CE3 HE3  sing N N 439 
TRP CZ2 CH2  doub Y N 440 
TRP CZ2 HZ2  sing N N 441 
TRP CZ3 CH2  sing Y N 442 
TRP CZ3 HZ3  sing N N 443 
TRP CH2 HH2  sing N N 444 
TRP OXT HXT  sing N N 445 
TYR N   CA   sing N N 446 
TYR N   H    sing N N 447 
TYR N   H2   sing N N 448 
TYR CA  C    sing N N 449 
TYR CA  CB   sing N N 450 
TYR CA  HA   sing N N 451 
TYR C   O    doub N N 452 
TYR C   OXT  sing N N 453 
TYR CB  CG   sing N N 454 
TYR CB  HB2  sing N N 455 
TYR CB  HB3  sing N N 456 
TYR CG  CD1  doub Y N 457 
TYR CG  CD2  sing Y N 458 
TYR CD1 CE1  sing Y N 459 
TYR CD1 HD1  sing N N 460 
TYR CD2 CE2  doub Y N 461 
TYR CD2 HD2  sing N N 462 
TYR CE1 CZ   doub Y N 463 
TYR CE1 HE1  sing N N 464 
TYR CE2 CZ   sing Y N 465 
TYR CE2 HE2  sing N N 466 
TYR CZ  OH   sing N N 467 
TYR OH  HH   sing N N 468 
TYR OXT HXT  sing N N 469 
VAL N   CA   sing N N 470 
VAL N   H    sing N N 471 
VAL N   H2   sing N N 472 
VAL CA  C    sing N N 473 
VAL CA  CB   sing N N 474 
VAL CA  HA   sing N N 475 
VAL C   O    doub N N 476 
VAL C   OXT  sing N N 477 
VAL CB  CG1  sing N N 478 
VAL CB  CG2  sing N N 479 
VAL CB  HB   sing N N 480 
VAL CG1 HG11 sing N N 481 
VAL CG1 HG12 sing N N 482 
VAL CG1 HG13 sing N N 483 
VAL CG2 HG21 sing N N 484 
VAL CG2 HG22 sing N N 485 
VAL CG2 HG23 sing N N 486 
VAL OXT HXT  sing N N 487 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Biotechnology and Biological Sciences Research Council (BBSRC)' 'United Kingdom' BB/T008741/10 1 
'European Research Council (ERC)'                                'European Union' 101021207     2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8AKL 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 2' 
_space_group.name_Hall        'P 2 2ab' 
_space_group.IT_number        18 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8RWS 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016634 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012698 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.017808 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . THR A 1 23  ? 10.85100 19.16000 -7.66800  1.000 36.14118 ? 26  THR A N    1 
ATOM   2    C CA   . THR A 1 23  ? 10.72900 17.80100 -7.15400  1.000 37.05971 ? 26  THR A CA   1 
ATOM   3    C C    . THR A 1 23  ? 10.69600 16.76400 -8.25900  1.000 37.59661 ? 26  THR A C    1 
ATOM   4    O O    . THR A 1 23  ? 11.15400 15.63500 -8.08500  1.000 37.15182 ? 26  THR A O    1 
ATOM   5    C CB   . THR A 1 23  ? 9.42500  17.62300 -6.35300  1.000 36.92022 ? 26  THR A CB   1 
ATOM   6    O OG1  . THR A 1 23  ? 9.37900  18.60700 -5.32400  1.000 33.98039 ? 26  THR A OG1  1 
ATOM   7    C CG2  . THR A 1 23  ? 9.34300  16.22100 -5.74900  1.000 37.80980 ? 26  THR A CG2  1 
ATOM   8    H HA   . THR A 1 23  ? 11.50000 17.63400 -6.59000  1.000 44.48000 ? 26  THR A HA   1 
ATOM   9    H HB   . THR A 1 23  ? 8.65900  17.73000 -6.93800  1.000 44.31000 ? 26  THR A HB   1 
ATOM   10   H HG1  . THR A 1 23  ? 9.36200  19.37600 -5.66200  1.000 40.79000 ? 26  THR A HG1  1 
ATOM   11   H HG21 . THR A 1 23  ? 8.49900  16.11000 -5.28400  1.000 45.38000 ? 26  THR A HG21 1 
ATOM   12   H HG22 . THR A 1 23  ? 9.40700  15.55400 -6.44900  1.000 45.38000 ? 26  THR A HG22 1 
ATOM   13   H HG23 . THR A 1 23  ? 10.06900 16.08800 -5.11900  1.000 45.38000 ? 26  THR A HG23 1 
ATOM   14   N N    . ASN A 1 24  ? 10.12200 17.15000 -9.39700  1.000 37.83612 ? 27  ASN A N    1 
ATOM   15   C CA   . ASN A 1 24  ? 9.99800  16.21700 -10.50800 1.000 38.48619 ? 27  ASN A CA   1 
ATOM   16   C C    . ASN A 1 24  ? 11.35200 15.64600 -10.90600 1.000 33.75931 ? 27  ASN A C    1 
ATOM   17   O O    . ASN A 1 24  ? 11.42200 14.54200 -11.45700 1.000 33.84616 ? 27  ASN A O    1 
ATOM   18   C CB   . ASN A 1 24  ? 9.33600  16.93500 -11.68200 1.000 43.85263 ? 27  ASN A CB   1 
ATOM   19   C CG   . ASN A 1 24  ? 8.75900  15.98100 -12.69300 1.000 48.93745 ? 27  ASN A CG   1 
ATOM   20   O OD1  . ASN A 1 24  ? 9.13000  16.00700 -13.86500 1.000 50.66134 ? 27  ASN A OD1  1 
ATOM   21   N ND2  . ASN A 1 24  ? 7.84800  15.12200 -12.24600 1.000 50.61923 ? 27  ASN A ND2  1 
ATOM   22   H H    . ASN A 1 24  ? 9.80100  17.93400 -9.54800  1.000 45.41000 ? 27  ASN A H    1 
ATOM   23   H HA   . ASN A 1 24  ? 9.43600  15.46900 -10.25300 1.000 46.19000 ? 27  ASN A HA   1 
ATOM   24   H HB2  . ASN A 1 24  ? 8.61500  17.49100 -11.34800 1.000 52.63000 ? 27  ASN A HB2  1 
ATOM   25   H HB3  . ASN A 1 24  ? 9.99700  17.48500 -12.13100 1.000 52.63000 ? 27  ASN A HB3  1 
ATOM   26   H HD21 . ASN A 1 24  ? 7.48900  14.55700 -12.78500 1.000 60.75000 ? 27  ASN A HD21 1 
ATOM   27   H HD22 . ASN A 1 24  ? 7.61800  15.13200 -11.41700 1.000 60.75000 ? 27  ASN A HD22 1 
ATOM   28   N N    . LEU A 1 25  ? 12.43800 16.37500 -10.63000 1.000 28.36919 ? 28  LEU A N    1 
ATOM   29   C CA   . LEU A 1 25  ? 13.76400 15.85500 -10.91700 1.000 28.81135 ? 28  LEU A CA   1 
ATOM   30   C C    . LEU A 1 25  ? 14.08800 14.61600 -10.09000 1.000 28.93505 ? 28  LEU A C    1 
ATOM   31   O O    . LEU A 1 25  ? 14.94000 13.82600 -10.50300 1.000 30.04571 ? 28  LEU A O    1 
ATOM   32   C CB   . LEU A 1 25  ? 14.82200 16.94100 -10.67700 1.000 28.91136 ? 28  LEU A CB   1 
ATOM   33   C CG   . LEU A 1 25  ? 14.60800 18.24900 -11.42800 1.000 28.26918 ? 28  LEU A CG   1 
ATOM   34   C CD1  . LEU A 1 25  ? 15.66700 19.27800 -11.07800 1.000 28.11390 ? 28  LEU A CD1  1 
ATOM   35   C CD2  . LEU A 1 25  ? 14.60500 17.99000 -12.93900 1.000 28.15074 ? 28  LEU A CD2  1 
ATOM   36   H H    . LEU A 1 25  ? 12.42800 17.16100 -10.28100 1.000 34.05000 ? 28  LEU A H    1 
ATOM   37   H HA   . LEU A 1 25  ? 13.80200 15.60600 -11.85400 1.000 34.58000 ? 28  LEU A HA   1 
ATOM   38   H HB2  . LEU A 1 25  ? 14.83300 17.15000 -9.73000  1.000 34.70000 ? 28  LEU A HB2  1 
ATOM   39   H HB3  . LEU A 1 25  ? 15.68400 16.59000 -10.94900 1.000 34.70000 ? 28  LEU A HB3  1 
ATOM   40   H HG   . LEU A 1 25  ? 13.74900 18.61500 -11.16400 1.000 33.93000 ? 28  LEU A HG   1 
ATOM   41   H HD11 . LEU A 1 25  ? 15.48200 20.09900 -11.56100 1.000 33.74000 ? 28  LEU A HD11 1 
ATOM   42   H HD12 . LEU A 1 25  ? 15.64400 19.44400 -10.12300 1.000 33.74000 ? 28  LEU A HD12 1 
ATOM   43   H HD13 . LEU A 1 25  ? 16.53800 18.93400 -11.33300 1.000 33.74000 ? 28  LEU A HD13 1 
ATOM   44   H HD21 . LEU A 1 25  ? 14.60100 18.84100 -13.40500 1.000 33.79000 ? 28  LEU A HD21 1 
ATOM   45   H HD22 . LEU A 1 25  ? 15.40100 17.48800 -13.17500 1.000 33.79000 ? 28  LEU A HD22 1 
ATOM   46   H HD23 . LEU A 1 25  ? 13.81200 17.48100 -13.17100 1.000 33.79000 ? 28  LEU A HD23 1 
ATOM   47   N N    . VAL A 1 26  ? 13.43400 14.41900 -8.94100  1.000 28.82451 ? 29  VAL A N    1 
ATOM   48   C CA   . VAL A 1 26  ? 13.80800 13.31000 -8.06400  1.000 28.57185 ? 29  VAL A CA   1 
ATOM   49   C C    . VAL A 1 26  ? 12.60800 12.52500 -7.53900  1.000 29.55354 ? 29  VAL A C    1 
ATOM   50   O O    . VAL A 1 26  ? 12.77700 11.62900 -6.71300  1.000 29.36142 ? 29  VAL A O    1 
ATOM   51   C CB   . VAL A 1 26  ? 14.70100 13.78700 -6.89600  1.000 27.72964 ? 29  VAL A CB   1 
ATOM   52   C CG1  . VAL A 1 26  ? 16.10100 14.15900 -7.38100  1.000 27.34802 ? 29  VAL A CG1  1 
ATOM   53   C CG2  . VAL A 1 26  ? 14.06000 14.97600 -6.18800  1.000 27.09272 ? 29  VAL A CG2  1 
ATOM   54   H H    . VAL A 1 26  ? 12.78500 14.90400 -8.65500  1.000 34.60000 ? 29  VAL A H    1 
ATOM   55   H HA   . VAL A 1 26  ? 14.30300 12.69000 -8.62200  1.000 34.30000 ? 29  VAL A HA   1 
ATOM   56   H HB   . VAL A 1 26  ? 14.78900 13.05500 -6.26500  1.000 33.28000 ? 29  VAL A HB   1 
ATOM   57   H HG11 . VAL A 1 26  ? 16.62100 14.48100 -6.62900  1.000 32.83000 ? 29  VAL A HG11 1 
ATOM   58   H HG12 . VAL A 1 26  ? 16.52200 13.37300 -7.76300  1.000 32.83000 ? 29  VAL A HG12 1 
ATOM   59   H HG13 . VAL A 1 26  ? 16.02700 14.85400 -8.05400  1.000 32.83000 ? 29  VAL A HG13 1 
ATOM   60   H HG21 . VAL A 1 26  ? 14.60000 15.21300 -5.41800  1.000 32.52000 ? 29  VAL A HG21 1 
ATOM   61   H HG22 . VAL A 1 26  ? 14.01500 15.72300 -6.80500  1.000 32.52000 ? 29  VAL A HG22 1 
ATOM   62   H HG23 . VAL A 1 26  ? 13.16700 14.72900 -5.90200  1.000 32.52000 ? 29  VAL A HG23 1 
ATOM   63   N N    . ALA A 1 27  ? 11.39500 12.81200 -8.02700  1.000 29.66671 ? 30  ALA A N    1 
ATOM   64   C CA   . ALA A 1 27  ? 10.21600 12.12500 -7.48900  1.000 29.75883 ? 30  ALA A CA   1 
ATOM   65   C C    . ALA A 1 27  ? 10.29900 10.60800 -7.67000  1.000 29.06927 ? 30  ALA A C    1 
ATOM   66   O O    . ALA A 1 27  ? 9.91100  9.84200  -6.77300  1.000 27.94019 ? 30  ALA A O    1 
ATOM   67   C CB   . ALA A 1 27  ? 8.94200  12.67000 -8.13600  1.000 30.20099 ? 30  ALA A CB   1 
ATOM   68   H H    . ALA A 1 27  ? 11.23300 13.38200 -8.64900  1.000 35.61000 ? 30  ALA A H    1 
ATOM   69   H HA   . ALA A 1 27  ? 10.17600 12.30500 -6.53700  1.000 35.72000 ? 30  ALA A HA   1 
ATOM   70   H HB1  . ALA A 1 27  ? 8.17700  12.19500 -7.77500  1.000 36.25000 ? 30  ALA A HB1  1 
ATOM   71   H HB2  . ALA A 1 27  ? 8.86800  13.61600 -7.93800  1.000 36.25000 ? 30  ALA A HB2  1 
ATOM   72   H HB3  . ALA A 1 27  ? 8.99300  12.53500 -9.09500  1.000 36.25000 ? 30  ALA A HB3  1 
ATOM   73   N N    . GLU A 1 28  ? 10.75800 10.14700 -8.83300  1.000 28.90873 ? 31  GLU A N    1 
ATOM   74   C CA   A GLU A 1 28  ? 10.92200 8.70900  -9.03100  0.420 28.88504 ? 31  GLU A CA   1 
ATOM   75   C CA   B GLU A 1 28  ? 10.92000 8.70900  -9.02800  0.580 28.90347 ? 31  GLU A CA   1 
ATOM   76   C C    . GLU A 1 28  ? 11.95700 8.11900  -8.08700  1.000 27.26116 ? 31  GLU A C    1 
ATOM   77   O O    . GLU A 1 28  ? 11.68000 7.07100  -7.47400  1.000 25.83994 ? 31  GLU A O    1 
ATOM   78   C CB   A GLU A 1 28  ? 11.24900 8.41300  -10.50000 0.420 30.56419 ? 31  GLU A CB   1 
ATOM   79   C CB   B GLU A 1 28  ? 11.23800 8.40900  -10.49700 0.580 30.61946 ? 31  GLU A CB   1 
ATOM   80   C CG   A GLU A 1 28  ? 11.64300 6.96300  -10.76900 0.420 31.92751 ? 31  GLU A CG   1 
ATOM   81   C CG   B GLU A 1 28  ? 10.00600 8.17900  -11.35500 0.580 31.92225 ? 31  GLU A CG   1 
ATOM   82   C CD   A GLU A 1 28  ? 11.28400 6.50600  -12.17500 0.420 33.21451 ? 31  GLU A CD   1 
ATOM   83   C CD   B GLU A 1 28  ? 10.34800 7.95000  -12.81500 0.580 33.23293 ? 31  GLU A CD   1 
ATOM   84   O OE1  A GLU A 1 28  ? 10.29300 7.02100  -12.73200 0.420 33.65930 ? 31  GLU A OE1  1 
ATOM   85   O OE1  B GLU A 1 28  ? 11.50600 7.58600  -13.10700 0.580 34.15146 ? 31  GLU A OE1  1 
ATOM   86   O OE2  A GLU A 1 28  ? 11.98900 5.63100  -12.72400 0.420 33.83564 ? 31  GLU A OE2  1 
ATOM   87   O OE2  B GLU A 1 28  ? 9.45900  8.13600  -13.67300 0.580 33.65930 ? 31  GLU A OE2  1 
ATOM   88   H H    A GLU A 1 28  ? 10.97600 10.63400 -9.50800  0.420 34.70000 ? 31  GLU A H    1 
ATOM   89   H H    B GLU A 1 28  ? 10.97700 10.63300 -9.50800  0.580 34.70000 ? 31  GLU A H    1 
ATOM   90   H HA   A GLU A 1 28  ? 10.07200 8.28300  -8.83800  0.420 34.67000 ? 31  GLU A HA   1 
ATOM   91   H HA   B GLU A 1 28  ? 10.07100 8.28400  -8.82900  0.580 34.69000 ? 31  GLU A HA   1 
ATOM   92   H HB2  A GLU A 1 28  ? 10.46700 8.61100  -11.03900 0.420 36.68000 ? 31  GLU A HB2  1 
ATOM   93   H HB2  B GLU A 1 28  ? 11.72300 9.16000  -10.87100 0.580 36.75000 ? 31  GLU A HB2  1 
ATOM   94   H HB3  A GLU A 1 28  ? 11.99100 8.97500  -10.77300 0.420 36.68000 ? 31  GLU A HB3  1 
ATOM   95   H HB3  B GLU A 1 28  ? 11.78300 7.60700  -10.54000 0.580 36.75000 ? 31  GLU A HB3  1 
ATOM   96   H HG2  A GLU A 1 28  ? 12.60300 6.87100  -10.66000 0.420 38.32000 ? 31  GLU A HG2  1 
ATOM   97   H HG2  B GLU A 1 28  ? 9.53400  7.39600  -11.02900 0.580 38.31000 ? 31  GLU A HG2  1 
ATOM   98   H HG3  A GLU A 1 28  ? 11.18100 6.38800  -10.14000 0.420 38.32000 ? 31  GLU A HG3  1 
ATOM   99   H HG3  B GLU A 1 28  ? 9.43100  8.95900  -11.29900 0.580 38.31000 ? 31  GLU A HG3  1 
ATOM   100  N N    . PRO A 1 29  ? 13.14900 8.70500  -7.92600  1.000 25.66887 ? 32  PRO A N    1 
ATOM   101  C CA   . PRO A 1 29  ? 14.07100 8.14800  -6.93600  1.000 23.51861 ? 32  PRO A CA   1 
ATOM   102  C C    . PRO A 1 29  ? 13.49900 8.15500  -5.52200  1.000 20.11031 ? 32  PRO A C    1 
ATOM   103  O O    . PRO A 1 29  ? 13.78500 7.20600  -4.78900  1.000 20.12873 ? 32  PRO A O    1 
ATOM   104  C CB   . PRO A 1 29  ? 15.36800 8.97000  -7.10200  1.000 25.36094 ? 32  PRO A CB   1 
ATOM   105  C CG   . PRO A 1 29  ? 15.08700 10.00700 -8.10500  1.000 26.65320 ? 32  PRO A CG   1 
ATOM   106  C CD   . PRO A 1 29  ? 13.82100 9.64700  -8.84100  1.000 25.28987 ? 32  PRO A CD   1 
ATOM   107  H HA   . PRO A 1 29  ? 14.30100 7.23500  -7.16900  1.000 28.23000 ? 32  PRO A HA   1 
ATOM   108  H HB2  . PRO A 1 29  ? 15.60600 9.37300  -6.25300  1.000 30.44000 ? 32  PRO A HB2  1 
ATOM   109  H HB3  . PRO A 1 29  ? 16.08200 8.38800  -7.40500  1.000 30.44000 ? 32  PRO A HB3  1 
ATOM   110  H HG2  . PRO A 1 29  ? 14.97900 10.85900 -7.65400  1.000 31.99000 ? 32  PRO A HG2  1 
ATOM   111  H HG3  . PRO A 1 29  ? 15.83100 10.05300 -8.72600  1.000 31.99000 ? 32  PRO A HG3  1 
ATOM   112  H HD2  . PRO A 1 29  ? 13.27300 10.43300 -8.98900  1.000 30.36000 ? 32  PRO A HD2  1 
ATOM   113  H HD3  . PRO A 1 29  ? 14.02400 9.21900  -9.68700  1.000 30.36000 ? 32  PRO A HD3  1 
ATOM   114  N N    . PHE A 1 30  ? 12.65900 9.13800  -5.13000  1.000 19.86817 ? 33  PHE A N    1 
ATOM   115  C CA   . PHE A 1 30  ? 12.07800 9.08900  -3.77500  1.000 19.05228 ? 33  PHE A CA   1 
ATOM   116  C C    . PHE A 1 30  ? 11.15300 7.88500  -3.61400  1.000 19.69447 ? 33  PHE A C    1 
ATOM   117  O O    . PHE A 1 30  ? 11.19300 7.19200  -2.59400  1.000 19.05755 ? 33  PHE A O    1 
ATOM   118  C CB   . PHE A 1 30  ? 11.27200 10.34600 -3.40000  1.000 19.23389 ? 33  PHE A CB   1 
ATOM   119  C CG   . PHE A 1 30  ? 12.09200 11.50500 -2.92100  1.000 17.59158 ? 33  PHE A CG   1 
ATOM   120  C CD1  . PHE A 1 30  ? 12.96800 11.38100 -1.84800  1.000 17.98900 ? 33  PHE A CD1  1 
ATOM   121  C CD2  . PHE A 1 30  ? 11.96000 12.73800 -3.52300  1.000 18.44695 ? 33  PHE A CD2  1 
ATOM   122  C CE1  . PHE A 1 30  ? 13.70900 12.46900 -1.43600  1.000 18.15744 ? 33  PHE A CE1  1 
ATOM   123  C CE2  . PHE A 1 30  ? 12.68300 13.81600 -3.10600  1.000 19.09439 ? 33  PHE A CE2  1 
ATOM   124  C CZ   . PHE A 1 30  ? 13.56600 13.68200 -2.06200  1.000 17.87846 ? 33  PHE A CZ   1 
ATOM   125  H H    . PHE A 1 30  ? 12.42300 9.81200  -5.60800  1.000 23.85000 ? 33  PHE A H    1 
ATOM   126  H HA   . PHE A 1 30  ? 12.83800 9.03700  -3.17500  1.000 22.87000 ? 33  PHE A HA   1 
ATOM   127  H HB2  . PHE A 1 30  ? 10.78100 10.64100 -4.18300  1.000 23.09000 ? 33  PHE A HB2  1 
ATOM   128  H HB3  . PHE A 1 30  ? 10.65400 10.11300 -2.68900  1.000 23.09000 ? 33  PHE A HB3  1 
ATOM   129  H HD1  . PHE A 1 30  ? 13.05300 10.56600 -1.40800  1.000 21.59000 ? 33  PHE A HD1  1 
ATOM   130  H HD2  . PHE A 1 30  ? 11.36400 12.83700 -4.23000  1.000 22.14000 ? 33  PHE A HD2  1 
ATOM   131  H HE1  . PHE A 1 30  ? 14.30900 12.38000 -0.73100  1.000 21.79000 ? 33  PHE A HE1  1 
ATOM   132  H HE2  . PHE A 1 30  ? 12.57900 14.63900 -3.52600  1.000 22.92000 ? 33  PHE A HE2  1 
ATOM   133  H HZ   . PHE A 1 30  ? 14.06700 14.41400 -1.78000  1.000 21.46000 ? 33  PHE A HZ   1 
ATOM   134  N N    . ALA A 1 31  ? 10.29100 7.63200  -4.59800  1.000 20.83408 ? 34  ALA A N    1 
ATOM   135  C CA   . ALA A 1 31  ? 9.38400  6.50000  -4.48800  1.000 21.09200 ? 34  ALA A CA   1 
ATOM   136  C C    . ALA A 1 31  ? 10.14800 5.18200  -4.41000  1.000 21.48152 ? 34  ALA A C    1 
ATOM   137  O O    . ALA A 1 31  ? 9.78800  4.29800  -3.62500  1.000 20.73670 ? 34  ALA A O    1 
ATOM   138  C CB   . ALA A 1 31  ? 8.41100  6.50600  -5.66700  1.000 22.07633 ? 34  ALA A CB   1 
ATOM   139  H H    . ALA A 1 31  ? 10.21400 8.09200  -5.32100  1.000 25.01000 ? 34  ALA A H    1 
ATOM   140  H HA   . ALA A 1 31  ? 8.86600  6.58300  -3.67200  1.000 25.32000 ? 34  ALA A HA   1 
ATOM   141  H HB1  . ALA A 1 31  ? 7.79800  5.76100  -5.57500  1.000 26.50000 ? 34  ALA A HB1  1 
ATOM   142  H HB2  . ALA A 1 31  ? 7.91900  7.34200  -5.66700  1.000 26.50000 ? 34  ALA A HB2  1 
ATOM   143  H HB3  . ALA A 1 31  ? 8.91500  6.42000  -6.49200  1.000 26.50000 ? 34  ALA A HB3  1 
ATOM   144  N N    . LYS A 1 32  ? 11.21100 5.03300  -5.20900  1.000 21.88947 ? 35  LYS A N    1 
ATOM   145  C CA   . LYS A 1 32  ? 12.00500 3.80900  -5.15400  1.000 21.60259 ? 35  LYS A CA   1 
ATOM   146  C C    . LYS A 1 32  ? 12.67300 3.65400  -3.79400  1.000 20.92883 ? 35  LYS A C    1 
ATOM   147  O O    . LYS A 1 32  ? 12.72900 2.55000  -3.23500  1.000 21.59996 ? 35  LYS A O    1 
ATOM   148  C CB   . LYS A 1 32  ? 13.04000 3.81800  -6.28000  1.000 25.36620 ? 35  LYS A CB   1 
ATOM   149  C CG   . LYS A 1 32  ? 14.03300 2.66500  -6.26100  1.000 29.71935 ? 35  LYS A CG   1 
ATOM   150  C CD   . LYS A 1 32  ? 13.35100 1.31000  -6.07400  1.000 33.74089 ? 35  LYS A CD   1 
ATOM   151  C CE   . LYS A 1 32  ? 14.12500 0.18600  -6.75300  1.000 36.75177 ? 35  LYS A CE   1 
ATOM   152  N NZ   . LYS A 1 32  ? 15.48300 -0.03200 -6.17100  1.000 38.13089 ? 35  LYS A NZ   1 
ATOM   153  H H    . LYS A 1 32  ? 11.48700 5.61500  -5.77900  1.000 26.28000 ? 35  LYS A H    1 
ATOM   154  H HA   . LYS A 1 32  ? 11.42600 3.04300  -5.28700  1.000 25.93000 ? 35  LYS A HA   1 
ATOM   155  H HB2  . LYS A 1 32  ? 12.57000 3.78100  -7.12800  1.000 30.44000 ? 35  LYS A HB2  1 
ATOM   156  H HB3  . LYS A 1 32  ? 13.55100 4.64000  -6.21900  1.000 30.44000 ? 35  LYS A HB3  1 
ATOM   157  H HG2  . LYS A 1 32  ? 14.51400 2.64600  -7.10300  1.000 35.67000 ? 35  LYS A HG2  1 
ATOM   158  H HG3  . LYS A 1 32  ? 14.65400 2.79200  -5.52600  1.000 35.67000 ? 35  LYS A HG3  1 
ATOM   159  H HD2  . LYS A 1 32  ? 13.29200 1.11000  -5.12700  1.000 40.50000 ? 35  LYS A HD2  1 
ATOM   160  H HD3  . LYS A 1 32  ? 12.46200 1.34400  -6.46200  1.000 40.50000 ? 35  LYS A HD3  1 
ATOM   161  H HE2  . LYS A 1 32  ? 13.62600 -0.64000 -6.66000  1.000 44.11000 ? 35  LYS A HE2  1 
ATOM   162  H HE3  . LYS A 1 32  ? 14.23600 0.40300  -7.69200  1.000 44.11000 ? 35  LYS A HE3  1 
ATOM   163  H HZ1  . LYS A 1 32  ? 15.89500 -0.69500 -6.59800  1.000 45.77000 ? 35  LYS A HZ1  1 
ATOM   164  H HZ2  . LYS A 1 32  ? 15.97100 0.70900  -6.25000  1.000 45.77000 ? 35  LYS A HZ2  1 
ATOM   165  H HZ3  . LYS A 1 32  ? 15.41500 -0.24100 -5.30900  1.000 45.77000 ? 35  LYS A HZ3  1 
ATOM   166  N N    . LEU A 1 33  ? 13.17900 4.75200  -3.24600  1.000 19.53655 ? 36  LEU A N    1 
ATOM   167  C CA   . LEU A 1 33  ? 13.80200 4.70200  -1.93100  1.000 18.45484 ? 36  LEU A CA   1 
ATOM   168  C C    . LEU A 1 33  ? 12.81500 4.23800  -0.86300  1.000 17.82056 ? 36  LEU A C    1 
ATOM   169  O O    . LEU A 1 33  ? 13.13800 3.36100  -0.04800  1.000 16.75464 ? 36  LEU A O    1 
ATOM   170  C CB   . LEU A 1 33  ? 14.36200 6.07200  -1.59200  1.000 18.39694 ? 36  LEU A CB   1 
ATOM   171  C CG   . LEU A 1 33  ? 15.15200 6.16700  -0.27900  1.000 18.75225 ? 36  LEU A CG   1 
ATOM   172  C CD1  . LEU A 1 33  ? 16.41300 5.30600  -0.29600  1.000 20.48667 ? 36  LEU A CD1  1 
ATOM   173  C CD2  . LEU A 1 33  ? 15.50200 7.62600  -0.01200  1.000 18.61013 ? 36  LEU A CD2  1 
ATOM   174  H H    . LEU A 1 33  ? 13.17500 5.53000  -3.61000  1.000 23.45000 ? 36  LEU A H    1 
ATOM   175  H HA   . LEU A 1 33  ? 14.53300 4.06400  -1.94700  1.000 22.15000 ? 36  LEU A HA   1 
ATOM   176  H HB2  . LEU A 1 33  ? 14.96000 6.34000  -2.30700  1.000 22.09000 ? 36  LEU A HB2  1 
ATOM   177  H HB3  . LEU A 1 33  ? 13.62100 6.69400  -1.52700  1.000 22.09000 ? 36  LEU A HB3  1 
ATOM   178  H HG   . LEU A 1 33  ? 14.60000 5.82600  0.44200   1.000 22.51000 ? 36  LEU A HG   1 
ATOM   179  H HD11 . LEU A 1 33  ? 16.93200 5.49100  0.50200   1.000 24.59000 ? 36  LEU A HD11 1 
ATOM   180  H HD12 . LEU A 1 33  ? 16.15600 4.37100  -0.31400  1.000 24.59000 ? 36  LEU A HD12 1 
ATOM   181  H HD13 . LEU A 1 33  ? 16.93200 5.52200  -1.08600  1.000 24.59000 ? 36  LEU A HD13 1 
ATOM   182  H HD21 . LEU A 1 33  ? 16.00500 7.68400  0.81500   1.000 22.34000 ? 36  LEU A HD21 1 
ATOM   183  H HD22 . LEU A 1 33  ? 16.03700 7.96200  -0.74800  1.000 22.34000 ? 36  LEU A HD22 1 
ATOM   184  H HD23 . LEU A 1 33  ? 14.68200 8.13900  0.06300   1.000 22.34000 ? 36  LEU A HD23 1 
ATOM   185  N N    . GLU A 1 34  ? 11.60200 4.80400  -0.84200  1.000 19.23389 ? 37  GLU A N    1 
ATOM   186  C CA   . GLU A 1 34  ? 10.68400 4.41200  0.22900   1.000 20.92883 ? 37  GLU A CA   1 
ATOM   187  C C    . GLU A 1 34  ? 10.17900 2.99100  0.01400   1.000 21.19728 ? 37  GLU A C    1 
ATOM   188  O O    . GLU A 1 34  ? 9.97500  2.25400  0.98300   1.000 20.71038 ? 37  GLU A O    1 
ATOM   189  C CB   . GLU A 1 34  ? 9.57000  5.44900  0.45400   1.000 23.13698 ? 37  GLU A CB   1 
ATOM   190  C CG   . GLU A 1 34  ? 8.33100  5.15300  -0.23900  1.000 20.63932 ? 37  GLU A CG   1 
ATOM   191  C CD   . GLU A 1 34  ? 7.34900  6.30400  -0.20500  1.000 16.80991 ? 37  GLU A CD   1 
ATOM   192  O OE1  . GLU A 1 34  ? 7.25600  7.09200  0.78700   1.000 15.17024 ? 37  GLU A OE1  1 
ATOM   193  O OE2  . GLU A 1 34  ? 6.63100  6.42800  -1.20400  1.000 16.98888 ? 37  GLU A OE2  1 
ATOM   194  H H    . GLU A 1 34  ? 11.30400 5.38300  -1.40400  1.000 23.09000 ? 37  GLU A H    1 
ATOM   195  H HA   . GLU A 1 34  ? 11.15800 4.41400  1.07500   1.000 25.12000 ? 37  GLU A HA   1 
ATOM   196  H HB2  . GLU A 1 34  ? 9.37400  5.49200  1.40200   1.000 27.77000 ? 37  GLU A HB2  1 
ATOM   197  H HB3  . GLU A 1 34  ? 9.88300  6.31200  0.14000   1.000 27.77000 ? 37  GLU A HB3  1 
ATOM   198  H HG2  . GLU A 1 34  ? 8.52700  4.95500  -1.16800  1.000 24.77000 ? 37  GLU A HG2  1 
ATOM   199  H HG3  . GLU A 1 34  ? 7.90900  4.38700  0.18200   1.000 24.77000 ? 37  GLU A HG3  1 
ATOM   200  N N    . GLN A 1 35  ? 10.06000 2.55200  -1.23900  1.000 22.78957 ? 38  GLN A N    1 
ATOM   201  C CA   . GLN A 1 35  ? 9.65300  1.17300  -1.47700  1.000 24.60032 ? 38  GLN A CA   1 
ATOM   202  C C    . GLN A 1 35  ? 10.71100 0.19100  -0.99200  1.000 22.88959 ? 38  GLN A C    1 
ATOM   203  O O    . GLN A 1 35  ? 10.37800 -0.82700 -0.37800  1.000 23.70547 ? 38  GLN A O    1 
ATOM   204  C CB   . GLN A 1 35  ? 9.30900  0.96900  -2.94800  1.000 28.00599 ? 38  GLN A CB   1 
ATOM   205  C CG   . GLN A 1 35  ? 7.98400  1.62100  -3.31000  1.000 31.03267 ? 38  GLN A CG   1 
ATOM   206  C CD   . GLN A 1 35  ? 7.88400  1.93600  -4.78000  1.000 33.26715 ? 38  GLN A CD   1 
ATOM   207  O OE1  . GLN A 1 35  ? 8.47000  1.24300  -5.61500  1.000 34.24095 ? 38  GLN A OE1  1 
ATOM   208  N NE2  . GLN A 1 35  ? 7.14800  2.99700  -5.10900  1.000 34.10935 ? 38  GLN A NE2  1 
ATOM   209  H H    . GLN A 1 35  ? 10.20600 3.02000  -1.94600  1.000 27.36000 ? 38  GLN A H    1 
ATOM   210  H HA   . GLN A 1 35  ? 8.84500  0.98800  -0.97400  1.000 29.53000 ? 38  GLN A HA   1 
ATOM   211  H HB2  . GLN A 1 35  ? 10.00400 1.36500  -3.49700  1.000 33.61000 ? 38  GLN A HB2  1 
ATOM   212  H HB3  . GLN A 1 35  ? 9.24200  0.01900  -3.13200  1.000 33.61000 ? 38  GLN A HB3  1 
ATOM   213  H HG2  . GLN A 1 35  ? 7.26000  1.01700  -3.08100  1.000 37.25000 ? 38  GLN A HG2  1 
ATOM   214  H HG3  . GLN A 1 35  ? 7.89300  2.45100  -2.81700  1.000 37.25000 ? 38  GLN A HG3  1 
ATOM   215  H HE21 . GLN A 1 35  ? 6.76200  3.46000  -4.49600  1.000 40.94000 ? 38  GLN A HE21 1 
ATOM   216  H HE22 . GLN A 1 35  ? 7.05900  3.21900  -5.93500  1.000 40.94000 ? 38  GLN A HE22 1 
ATOM   217  N N    . ASP A 1 36  ? 11.99000 0.48700  -1.23200  1.000 21.28150 ? 39  ASP A N    1 
ATOM   218  C CA   . ASP A 1 36  ? 13.05200 -0.35900 -0.69500  1.000 21.46310 ? 39  ASP A CA   1 
ATOM   219  C C    . ASP A 1 36  ? 13.06500 -0.33800 0.83200   1.000 19.47602 ? 39  ASP A C    1 
ATOM   220  O O    . ASP A 1 36  ? 13.33100 -1.36600 1.47400   1.000 21.48152 ? 39  ASP A O    1 
ATOM   221  C CB   . ASP A 1 36  ? 14.39800 0.11200  -1.23100  1.000 24.01604 ? 39  ASP A CB   1 
ATOM   222  C CG   . ASP A 1 36  ? 14.57800 -0.20300 -2.69500  1.000 28.33498 ? 39  ASP A CG   1 
ATOM   223  O OD1  . ASP A 1 36  ? 13.78100 -0.99000 -3.24800  1.000 30.85633 ? 39  ASP A OD1  1 
ATOM   224  O OD2  . ASP A 1 36  ? 15.51700 0.34700  -3.28500  1.000 29.25351 ? 39  ASP A OD2  1 
ATOM   225  H H    . ASP A 1 36  ? 12.26300 1.15800  -1.69400  1.000 25.55000 ? 39  ASP A H    1 
ATOM   226  H HA   . ASP A 1 36  ? 12.89900 -1.27200 -0.98400  1.000 25.76000 ? 39  ASP A HA   1 
ATOM   227  H HB2  . ASP A 1 36  ? 14.46500 1.07400  -1.11900  1.000 28.83000 ? 39  ASP A HB2  1 
ATOM   228  H HB3  . ASP A 1 36  ? 15.10800 -0.32900 -0.73800  1.000 28.83000 ? 39  ASP A HB3  1 
ATOM   229  N N    . PHE A 1 37  ? 12.81300 0.83100  1.42500   1.000 17.72581 ? 40  PHE A N    1 
ATOM   230  C CA   . PHE A 1 37  ? 12.74000 0.96500  2.88300   1.000 17.63106 ? 40  PHE A CA   1 
ATOM   231  C C    . PHE A 1 37  ? 11.56800 0.18400  3.45900   1.000 18.34957 ? 40  PHE A C    1 
ATOM   232  O O    . PHE A 1 37  ? 11.65400 -0.34400 4.57900   1.000 20.00766 ? 40  PHE A O    1 
ATOM   233  C CB   . PHE A 1 37  ? 12.64600 2.45900  3.22100   1.000 16.98888 ? 40  PHE A CB   1 
ATOM   234  C CG   . PHE A 1 37  ? 12.28500 2.75600  4.65300   1.000 16.59936 ? 40  PHE A CG   1 
ATOM   235  C CD1  . PHE A 1 37  ? 13.10900 2.35100  5.68800   1.000 16.88097 ? 40  PHE A CD1  1 
ATOM   236  C CD2  . PHE A 1 37  ? 11.13200 3.47000  4.95800   1.000 17.27576 ? 40  PHE A CD2  1 
ATOM   237  C CE1  . PHE A 1 37  ? 12.77100 2.62200  7.00300   1.000 17.32839 ? 40  PHE A CE1  1 
ATOM   238  C CE2  . PHE A 1 37  ? 10.79800 3.74700  6.26700   1.000 17.37577 ? 40  PHE A CE2  1 
ATOM   239  C CZ   . PHE A 1 37  ? 11.62200 3.32000  7.29200   1.000 17.65738 ? 40  PHE A CZ   1 
ATOM   240  H H    . PHE A 1 37  ? 12.67900 1.56900  1.00400   1.000 21.28000 ? 40  PHE A H    1 
ATOM   241  H HA   . PHE A 1 37  ? 13.53900 0.60500  3.29800   1.000 21.16000 ? 40  PHE A HA   1 
ATOM   242  H HB2  . PHE A 1 37  ? 13.50700 2.86900  3.04500   1.000 20.39000 ? 40  PHE A HB2  1 
ATOM   243  H HB3  . PHE A 1 37  ? 11.96600 2.86000  2.65800   1.000 20.39000 ? 40  PHE A HB3  1 
ATOM   244  H HD1  . PHE A 1 37  ? 13.89600 1.89300  5.49900   1.000 20.26000 ? 40  PHE A HD1  1 
ATOM   245  H HD2  . PHE A 1 37  ? 10.57900 3.76400  4.27100   1.000 20.74000 ? 40  PHE A HD2  1 
ATOM   246  H HE1  . PHE A 1 37  ? 13.32300 2.33200  7.69300   1.000 20.80000 ? 40  PHE A HE1  1 
ATOM   247  H HE2  . PHE A 1 37  ? 10.02100 4.22000  6.45900   1.000 20.86000 ? 40  PHE A HE2  1 
ATOM   248  H HZ   . PHE A 1 37  ? 11.39900 3.50400  8.17600   1.000 21.20000 ? 40  PHE A HZ   1 
ATOM   249  N N    . GLY A 1 38  ? 10.48000 0.08000  2.71300   1.000 18.68645 ? 41  GLY A N    1 
ATOM   250  C CA   . GLY A 1 38  ? 9.30100  -0.61700 3.20300   1.000 19.55234 ? 41  GLY A CA   1 
ATOM   251  C C    . GLY A 1 38  ? 8.37100  0.22500  4.04500   1.000 19.61288 ? 41  GLY A C    1 
ATOM   252  O O    . GLY A 1 38  ? 7.64600  -0.31800 4.88900   1.000 21.85525 ? 41  GLY A O    1 
ATOM   253  H H    . GLY A 1 38  ? 10.39800 0.40200  1.92000   1.000 22.43000 ? 41  GLY A H    1 
ATOM   254  H HA2  . GLY A 1 38  ? 8.79500  -0.94500 2.44200   1.000 23.47000 ? 41  GLY A HA2  1 
ATOM   255  H HA3  . GLY A 1 38  ? 9.58700  -1.37100 3.74100   1.000 23.47000 ? 41  GLY A HA3  1 
ATOM   256  N N    . GLY A 1 39  ? 8.37900  1.52400  3.85500   1.000 16.33091 ? 42  GLY A N    1 
ATOM   257  C CA   . GLY A 1 39  ? 7.53400  2.43000  4.60800   1.000 16.26774 ? 42  GLY A CA   1 
ATOM   258  C C    . GLY A 1 39  ? 7.26600  3.68600  3.82800   1.000 15.96770 ? 42  GLY A C    1 
ATOM   259  O O    . GLY A 1 39  ? 7.16900  3.66100  2.59200   1.000 18.88384 ? 42  GLY A O    1 
ATOM   260  H H    . GLY A 1 39  ? 8.87900  1.92100  3.27900   1.000 19.60000 ? 42  GLY A H    1 
ATOM   261  H HA2  . GLY A 1 39  ? 6.68700  2.00000  4.80600   1.000 19.53000 ? 42  GLY A HA2  1 
ATOM   262  H HA3  . GLY A 1 39  ? 7.96900  2.66800  5.44200   1.000 19.53000 ? 42  GLY A HA3  1 
ATOM   263  N N    . SER A 1 40  ? 7.14700  4.79500  4.54700   1.000 14.22802 ? 43  SER A N    1 
ATOM   264  C CA   . SER A 1 40  ? 6.88500  6.10500  3.97400   1.000 14.44647 ? 43  SER A CA   1 
ATOM   265  C C    . SER A 1 40  ? 7.98100  7.07100  4.37900   1.000 13.92799 ? 43  SER A C    1 
ATOM   266  O O    . SER A 1 40  ? 8.42400  7.07200  5.53800   1.000 13.71743 ? 43  SER A O    1 
ATOM   267  C CB   . SER A 1 40  ? 5.55300  6.68100  4.45900   1.000 15.68872 ? 43  SER A CB   1 
ATOM   268  O OG   . SER A 1 40  ? 4.51100  5.81300  4.09500   1.000 17.39156 ? 43  SER A OG   1 
ATOM   269  H H    . SER A 1 40  ? 7.21800  4.81300  5.40400   1.000 17.08000 ? 43  SER A H    1 
ATOM   270  H HA   . SER A 1 40  ? 6.86300  6.01600  3.00800   1.000 17.35000 ? 43  SER A HA   1 
ATOM   271  H HB2  . SER A 1 40  ? 5.57500  6.77100  5.42400   1.000 18.83000 ? 43  SER A HB2  1 
ATOM   272  H HB3  . SER A 1 40  ? 5.40900  7.54700  4.04700   1.000 18.83000 ? 43  SER A HB3  1 
ATOM   273  H HG   . SER A 1 40  ? 3.77500  6.12400  4.35400   1.000 20.88000 ? 43  SER A HG   1 
ATOM   274  N N    . ILE A 1 41  ? 8.41500  7.88300  3.41700   1.000 12.86470 ? 44  ILE A N    1 
ATOM   275  C CA   . ILE A 1 41  ? 9.41200  8.91800  3.62500   1.000 12.69626 ? 44  ILE A CA   1 
ATOM   276  C C    . ILE A 1 41  ? 8.77400  10.25500 3.27900   1.000 11.96986 ? 44  ILE A C    1 
ATOM   277  O O    . ILE A 1 41  ? 8.09600  10.38900 2.24300   1.000 14.15959 ? 44  ILE A O    1 
ATOM   278  C CB   . ILE A 1 41  ? 10.65900 8.68300  2.75800   1.000 13.67796 ? 44  ILE A CB   1 
ATOM   279  C CG1  . ILE A 1 41  ? 11.29000 7.34300  3.09300   1.000 15.30710 ? 44  ILE A CG1  1 
ATOM   280  C CG2  . ILE A 1 41  ? 11.62500 9.84100  2.91500   1.000 16.29143 ? 44  ILE A CG2  1 
ATOM   281  C CD1  . ILE A 1 41  ? 12.36900 6.94100  2.08700   1.000 16.48882 ? 44  ILE A CD1  1 
ATOM   282  H H    . ILE A 1 41  ? 8.13200  7.84800  2.60600   1.000 15.45000 ? 44  ILE A H    1 
ATOM   283  H HA   . ILE A 1 41  ? 9.68000  8.92600  4.55700   1.000 15.24000 ? 44  ILE A HA   1 
ATOM   284  H HB   . ILE A 1 41  ? 10.40300 8.64800  1.82400   1.000 16.42000 ? 44  ILE A HB   1 
ATOM   285  H HG12 . ILE A 1 41  ? 11.69900 7.39400  3.97100   1.000 18.38000 ? 44  ILE A HG12 1 
ATOM   286  H HG13 . ILE A 1 41  ? 10.60200 6.65800  3.08700   1.000 18.38000 ? 44  ILE A HG13 1 
ATOM   287  H HG21 . ILE A 1 41  ? 12.48300 9.59000  2.53900   1.000 19.56000 ? 44  ILE A HG21 1 
ATOM   288  H HG22 . ILE A 1 41  ? 11.27100 10.61300 2.44600   1.000 19.56000 ? 44  ILE A HG22 1 
ATOM   289  H HG23 . ILE A 1 41  ? 11.72400 10.04400 3.85900   1.000 19.56000 ? 44  ILE A HG23 1 
ATOM   290  H HD11 . ILE A 1 41  ? 12.56000 5.99500  2.19000   1.000 19.79000 ? 44  ILE A HD11 1 
ATOM   291  H HD12 . ILE A 1 41  ? 12.04700 7.11700  1.19000   1.000 19.79000 ? 44  ILE A HD12 1 
ATOM   292  H HD13 . ILE A 1 41  ? 13.17000 7.46000  2.25900   1.000 19.79000 ? 44  ILE A HD13 1 
ATOM   293  N N    . GLY A 1 42  ? 8.96500  11.22900 4.15300   1.000 11.16450 ? 45  GLY A N    1 
ATOM   294  C CA   . GLY A 1 42  ? 8.47900  12.56800 3.97200   1.000 12.55150 ? 45  GLY A CA   1 
ATOM   295  C C    . GLY A 1 42  ? 9.61600  13.56200 3.94900   1.000 11.63034 ? 45  GLY A C    1 
ATOM   296  O O    . GLY A 1 42  ? 10.44300 13.57800 4.86900   1.000 11.95670 ? 45  GLY A O    1 
ATOM   297  H H    . GLY A 1 42  ? 9.39400  11.12700 4.89100   1.000 13.41000 ? 45  GLY A H    1 
ATOM   298  H HA2  . GLY A 1 42  ? 7.99500  12.62800 3.13300   1.000 15.07000 ? 45  GLY A HA2  1 
ATOM   299  H HA3  . GLY A 1 42  ? 7.87900  12.79700 4.69900   1.000 15.07000 ? 45  GLY A HA3  1 
ATOM   300  N N    . VAL A 1 43  ? 9.66800  14.40900 2.92800   1.000 12.44097 ? 46  VAL A N    1 
ATOM   301  C CA   . VAL A 1 43  ? 10.76700 15.34100 2.74900   1.000 13.11999 ? 46  VAL A CA   1 
ATOM   302  C C    . VAL A 1 43  ? 10.22600 16.69900 2.34700   1.000 12.72521 ? 46  VAL A C    1 
ATOM   303  O O    . VAL A 1 43  ? 9.36000  16.79900 1.46700   1.000 12.93313 ? 46  VAL A O    1 
ATOM   304  C CB   . VAL A 1 43  ? 11.73100 14.84400 1.64300   1.000 13.48846 ? 46  VAL A CB   1 
ATOM   305  C CG1  . VAL A 1 43  ? 12.84400 15.84800 1.39400   1.000 14.70966 ? 46  VAL A CG1  1 
ATOM   306  C CG2  . VAL A 1 43  ? 12.22700 13.43900 1.96000   1.000 14.61228 ? 46  VAL A CG2  1 
ATOM   307  H H    . VAL A 1 43  ? 9.06600  14.46200 2.31600   1.000 14.93000 ? 46  VAL A H    1 
ATOM   308  H HA   . VAL A 1 43  ? 11.23200 15.43200 3.59500   1.000 15.75000 ? 46  VAL A HA   1 
ATOM   309  H HB   . VAL A 1 43  ? 11.25500 14.77600 0.80100   1.000 16.19000 ? 46  VAL A HB   1 
ATOM   310  H HG11 . VAL A 1 43  ? 13.54700 15.42000 0.88100   1.000 17.66000 ? 46  VAL A HG11 1 
ATOM   311  H HG12 . VAL A 1 43  ? 12.48500 16.60100 0.89800   1.000 17.66000 ? 46  VAL A HG12 1 
ATOM   312  H HG13 . VAL A 1 43  ? 13.19300 16.15100 2.24600   1.000 17.66000 ? 46  VAL A HG13 1 
ATOM   313  H HG21 . VAL A 1 43  ? 12.89400 13.18500 1.30300   1.000 17.54000 ? 46  VAL A HG21 1 
ATOM   314  H HG22 . VAL A 1 43  ? 12.61800 13.43500 2.84700   1.000 17.54000 ? 46  VAL A HG22 1 
ATOM   315  H HG23 . VAL A 1 43  ? 11.47700 12.82500 1.92500   1.000 17.54000 ? 46  VAL A HG23 1 
ATOM   316  N N    A TYR A 1 44  ? 10.72900 17.73800 2.98400   0.520 12.50413 ? 47  TYR A N    1 
ATOM   317  N N    B TYR A 1 44  ? 10.78600 17.75600 2.93800   0.480 12.70415 ? 47  TYR A N    1 
ATOM   318  C CA   A TYR A 1 44  ? 10.61000 19.08900 2.46800   0.520 12.78048 ? 47  TYR A CA   1 
ATOM   319  C CA   B TYR A 1 44  ? 10.57000 19.11600 2.45100   0.480 12.85944 ? 47  TYR A CA   1 
ATOM   320  C C    A TYR A 1 44  ? 11.98600 19.71500 2.55500   0.520 12.96471 ? 47  TYR A C    1 
ATOM   321  C C    B TYR A 1 44  ? 11.85400 19.90800 2.60300   0.480 12.95155 ? 47  TYR A C    1 
ATOM   322  O O    A TYR A 1 44  ? 12.69700 19.54000 3.55300   0.520 12.35938 ? 47  TYR A O    1 
ATOM   323  O O    B TYR A 1 44  ? 12.34800 20.08900 3.72100   0.480 12.53835 ? 47  TYR A O    1 
ATOM   324  C CB   A TYR A 1 44  ? 9.62000  19.92500 3.23700   0.520 12.43833 ? 47  TYR A CB   1 
ATOM   325  C CB   B TYR A 1 44  ? 9.43600  19.82600 3.18500   0.480 12.54624 ? 47  TYR A CB   1 
ATOM   326  C CG   A TYR A 1 44  ? 9.01000  21.06500 2.43900   0.520 11.66719 ? 47  TYR A CG   1 
ATOM   327  C CG   B TYR A 1 44  ? 9.03200  21.14900 2.55500   0.480 12.67257 ? 47  TYR A CG   1 
ATOM   328  C CD1  A TYR A 1 44  ? 8.21400  20.82500 1.32600   0.520 11.75930 ? 47  TYR A CD1  1 
ATOM   329  C CD1  B TYR A 1 44  ? 8.17400  21.17900 1.47000   0.480 12.96998 ? 47  TYR A CD1  1 
ATOM   330  C CD2  A TYR A 1 44  ? 9.21300  22.38500 2.81700   0.520 12.46202 ? 47  TYR A CD2  1 
ATOM   331  C CD2  B TYR A 1 44  ? 9.49900  22.36500 3.04900   0.480 13.87535 ? 47  TYR A CD2  1 
ATOM   332  C CE1  A TYR A 1 44  ? 7.63600  21.87000 0.63800   0.520 12.54624 ? 47  TYR A CE1  1 
ATOM   333  C CE1  B TYR A 1 44  ? 7.77900  22.36700 0.90100   0.480 12.99630 ? 47  TYR A CE1  1 
ATOM   334  C CE2  A TYR A 1 44  ? 8.64400  23.43200 2.13000   0.520 13.40687 ? 47  TYR A CE2  1 
ATOM   335  C CE2  B TYR A 1 44  ? 9.10500  23.57400 2.47800   0.480 13.55162 ? 47  TYR A CE2  1 
ATOM   336  C CZ   A TYR A 1 44  ? 7.86100  23.17000 1.03800   0.520 12.63836 ? 47  TYR A CZ   1 
ATOM   337  C CZ   B TYR A 1 44  ? 8.24100  23.56400 1.39800   0.480 13.65690 ? 47  TYR A CZ   1 
ATOM   338  O OH   A TYR A 1 44  ? 7.27000  24.19900 0.35100   0.520 14.05168 ? 47  TYR A OH   1 
ATOM   339  O OH   B TYR A 1 44  ? 7.82400  24.74300 0.82300   0.480 16.32564 ? 47  TYR A OH   1 
ATOM   340  H H    A TYR A 1 44  ? 11.15300 17.68600 3.73000   0.520 15.01000 ? 47  TYR A H    1 
ATOM   341  H H    B TYR A 1 44  ? 11.29800 17.70900 3.62700   0.480 15.25000 ? 47  TYR A H    1 
ATOM   342  H HA   A TYR A 1 44  ? 10.29700 19.07100 1.55000   0.520 15.34000 ? 47  TYR A HA   1 
ATOM   343  H HA   B TYR A 1 44  ? 10.33800 19.06300 1.51000   0.480 15.44000 ? 47  TYR A HA   1 
ATOM   344  H HB2  A TYR A 1 44  ? 8.89500  19.35300 3.53300   0.520 14.93000 ? 47  TYR A HB2  1 
ATOM   345  H HB2  B TYR A 1 44  ? 8.65600  19.24900 3.18700   0.480 15.06000 ? 47  TYR A HB2  1 
ATOM   346  H HB3  A TYR A 1 44  ? 10.07100 20.31200 4.00300   0.520 14.93000 ? 47  TYR A HB3  1 
ATOM   347  H HB3  B TYR A 1 44  ? 9.71800  20.00500 4.09500   0.480 15.06000 ? 47  TYR A HB3  1 
ATOM   348  H HD1  A TYR A 1 44  ? 8.07000  19.95100 1.04200   0.520 14.12000 ? 47  TYR A HD1  1 
ATOM   349  H HD1  B TYR A 1 44  ? 7.85700  20.37900 1.11900   0.480 15.57000 ? 47  TYR A HD1  1 
ATOM   350  H HD2  A TYR A 1 44  ? 9.74800  22.56700 3.55600   0.520 14.96000 ? 47  TYR A HD2  1 
ATOM   351  H HD2  B TYR A 1 44  ? 10.08400 22.37100 3.77300   0.480 16.66000 ? 47  TYR A HD2  1 
ATOM   352  H HE1  A TYR A 1 44  ? 7.09300  21.69800 -0.09700  0.520 15.07000 ? 47  TYR A HE1  1 
ATOM   353  H HE1  B TYR A 1 44  ? 7.19700  22.36100 0.17500   0.480 15.60000 ? 47  TYR A HE1  1 
ATOM   354  H HE2  A TYR A 1 44  ? 8.78900  24.30800 2.40500   0.520 16.09000 ? 47  TYR A HE2  1 
ATOM   355  H HE2  B TYR A 1 44  ? 9.42000  24.37900 2.82000   0.480 16.27000 ? 47  TYR A HE2  1 
ATOM   356  H HH   A TYR A 1 44  ? 7.45300  24.93300 0.71700   0.520 16.87000 ? 47  TYR A HH   1 
ATOM   357  H HH   B TYR A 1 44  ? 8.10400  25.39600 1.27100   0.480 19.60000 ? 47  TYR A HH   1 
ATOM   358  N N    . ALA A 1 45  ? 12.39000 20.38500 1.48700   1.000 12.82259 ? 48  ALA A N    1 
ATOM   359  C CA   . ALA A 1 45  ? 13.66000 21.09600 1.46200   1.000 12.91997 ? 48  ALA A CA   1 
ATOM   360  C C    . ALA A 1 45  ? 13.47600 22.42100 0.74900   1.000 13.88061 ? 48  ALA A C    1 
ATOM   361  O O    . ALA A 1 45  ? 12.87500 22.47600 -0.33400  1.000 15.35447 ? 48  ALA A O    1 
ATOM   362  C CB   . ALA A 1 45  ? 14.74100 20.28200 0.77100   1.000 12.60677 ? 48  ALA A CB   1 
ATOM   363  H H    A ALA A 1 45  ? 11.94100 20.44500 0.75600   0.520 15.40000 ? 48  ALA A H    1 
ATOM   364  H H    B ALA A 1 45  ? 12.02600 20.30700 0.71200   0.480 15.40000 ? 48  ALA A H    1 
ATOM   365  H HA   . ALA A 1 45  ? 13.95000 21.27200 2.37000   1.000 15.51000 ? 48  ALA A HA   1 
ATOM   366  H HB1  . ALA A 1 45  ? 15.56800 20.78700 0.77500   1.000 15.14000 ? 48  ALA A HB1  1 
ATOM   367  H HB2  . ALA A 1 45  ? 14.86100 19.44600 1.24800   1.000 15.14000 ? 48  ALA A HB2  1 
ATOM   368  H HB3  . ALA A 1 45  ? 14.46700 20.10400 -0.14300  1.000 15.14000 ? 48  ALA A HB3  1 
ATOM   369  N N    A MET A 1 46  ? 13.93400 23.48800 1.39100   0.250 13.81218 ? 49  MET A N    1 
ATOM   370  N N    B MET A 1 46  ? 14.04600 23.47500 1.32300   0.750 14.55438 ? 49  MET A N    1 
ATOM   371  C CA   A MET A 1 46  ? 13.86500 24.83400 0.84700   0.250 14.99127 ? 49  MET A CA   1 
ATOM   372  C CA   B MET A 1 46  ? 13.85600 24.85300 0.87600   0.750 16.87571 ? 49  MET A CA   1 
ATOM   373  C C    A MET A 1 46  ? 15.27300 25.34500 0.57100   0.250 15.18340 ? 49  MET A C    1 
ATOM   374  C C    B MET A 1 46  ? 15.21900 25.49000 0.63400   0.750 15.77294 ? 49  MET A C    1 
ATOM   375  O O    A MET A 1 46  ? 16.18000 25.16700 1.38900   0.250 14.79388 ? 49  MET A O    1 
ATOM   376  O O    B MET A 1 46  ? 16.05400 25.53700 1.54300   0.750 13.99115 ? 49  MET A O    1 
ATOM   377  C CB   A MET A 1 46  ? 13.18500 25.77700 1.84000   0.250 16.15194 ? 49  MET A CB   1 
ATOM   378  C CB   B MET A 1 46  ? 13.09500 25.59600 1.97400   0.750 21.61575 ? 49  MET A CB   1 
ATOM   379  C CG   A MET A 1 46  ? 13.20500 27.23200 1.42100   0.250 17.77318 ? 49  MET A CG   1 
ATOM   380  C CG   B MET A 1 46  ? 12.95000 27.08200 1.84400   0.750 25.52411 ? 49  MET A CG   1 
ATOM   381  S SD   A MET A 1 46  ? 12.12300 27.56600 0.03000   0.250 18.72593 ? 49  MET A SD   1 
ATOM   382  S SD   B MET A 1 46  ? 12.47000 27.72400 3.46800   0.750 28.36393 ? 49  MET A SD   1 
ATOM   383  C CE   A MET A 1 46  ? 10.52000 27.39900 0.81800   0.250 18.68645 ? 49  MET A CE   1 
ATOM   384  C CE   B MET A 1 46  ? 11.02200 26.71500 3.84100   0.750 26.14261 ? 49  MET A CE   1 
ATOM   385  H H    A MET A 1 46  ? 14.30000 23.45400 2.16900   0.250 16.58000 ? 49  MET A H    1 
ATOM   386  H H    B MET A 1 46  ? 14.56900 23.41600 2.00300   0.750 17.47000 ? 49  MET A H    1 
ATOM   387  H HA   A MET A 1 46  ? 13.35500 24.82200 0.02200   0.250 18.00000 ? 49  MET A HA   1 
ATOM   388  H HA   B MET A 1 46  ? 13.36500 24.88900 0.04000   0.750 20.26000 ? 49  MET A HA   1 
ATOM   389  H HB2  A MET A 1 46  ? 12.25700 25.51000 1.93600   0.250 19.39000 ? 49  MET A HB2  1 
ATOM   390  H HB2  B MET A 1 46  ? 12.19700 25.23100 2.01100   0.750 25.94000 ? 49  MET A HB2  1 
ATOM   391  H HB3  A MET A 1 46  ? 13.63900 25.71000 2.69400   0.250 19.39000 ? 49  MET A HB3  1 
ATOM   392  H HB3  B MET A 1 46  ? 13.55400 25.43400 2.81400   0.750 25.94000 ? 49  MET A HB3  1 
ATOM   393  H HG2  A MET A 1 46  ? 12.91300 27.78000 2.16600   0.250 21.33000 ? 49  MET A HG2  1 
ATOM   394  H HG2  B MET A 1 46  ? 13.79300 27.48100 1.57600   0.750 30.64000 ? 49  MET A HG2  1 
ATOM   395  H HG3  A MET A 1 46  ? 14.10800 27.47500 1.16400   0.250 21.33000 ? 49  MET A HG3  1 
ATOM   396  H HG3  B MET A 1 46  ? 12.26000 27.29700 1.19700   0.750 30.64000 ? 49  MET A HG3  1 
ATOM   397  H HE1  A MET A 1 46  ? 9.83300  27.69500 0.20200   0.250 22.43000 ? 49  MET A HE1  1 
ATOM   398  H HE1  B MET A 1 46  ? 10.59600 27.05700 4.64300   0.750 31.38000 ? 49  MET A HE1  1 
ATOM   399  H HE2  A MET A 1 46  ? 10.37800 26.46800 1.05100   0.250 22.43000 ? 49  MET A HE2  1 
ATOM   400  H HE2  B MET A 1 46  ? 10.40400 26.76100 3.09400   0.750 31.38000 ? 49  MET A HE2  1 
ATOM   401  H HE3  A MET A 1 46  ? 10.50400 27.94600 1.61900   0.250 22.43000 ? 49  MET A HE3  1 
ATOM   402  H HE3  B MET A 1 46  ? 11.30300 25.79700 3.98100   0.750 31.38000 ? 49  MET A HE3  1 
ATOM   403  N N    . ASP A 1 47  ? 15.44300 25.97800 -0.58700  1.000 15.37553 ? 50  ASP A N    1 
ATOM   404  C CA   . ASP A 1 47  ? 16.61100 26.79400 -0.89200  1.000 16.69411 ? 50  ASP A CA   1 
ATOM   405  C C    . ASP A 1 47  ? 16.23000 28.22600 -0.52600  1.000 16.79675 ? 50  ASP A C    1 
ATOM   406  O O    . ASP A 1 47  ? 15.35800 28.82500 -1.16600  1.000 17.59685 ? 50  ASP A O    1 
ATOM   407  C CB   . ASP A 1 47  ? 16.94900 26.67700 -2.37600  1.000 17.94162 ? 50  ASP A CB   1 
ATOM   408  C CG   . ASP A 1 47  ? 18.16900 27.47400 -2.76300  1.000 19.95502 ? 50  ASP A CG   1 
ATOM   409  O OD1  . ASP A 1 47  ? 18.54100 28.43000 -2.05400  1.000 20.16294 ? 50  ASP A OD1  1 
ATOM   410  O OD2  . ASP A 1 47  ? 18.74900 27.14700 -3.81400  1.000 20.94725 ? 50  ASP A OD2  1 
ATOM   411  H H    A ASP A 1 47  ? 14.87500 25.94900 -1.23200  0.250 18.46000 ? 50  ASP A H    1 
ATOM   412  H H    B ASP A 1 47  ? 14.92400 25.84800 -1.26000  0.750 18.46000 ? 50  ASP A H    1 
ATOM   413  H HA   . ASP A 1 47  ? 17.38800 26.51500 -0.38300  1.000 20.04000 ? 50  ASP A HA   1 
ATOM   414  H HB2  . ASP A 1 47  ? 17.12000 25.74600 -2.58800  1.000 21.54000 ? 50  ASP A HB2  1 
ATOM   415  H HB3  . ASP A 1 47  ? 16.20000 27.00400 -2.89700  1.000 21.54000 ? 50  ASP A HB3  1 
ATOM   416  N N    . THR A 1 48  ? 16.82300 28.76000 0.54200   1.000 15.88875 ? 51  THR A N    1 
ATOM   417  C CA   . THR A 1 48  ? 16.38800 30.05600 1.04600   1.000 17.40735 ? 51  THR A CA   1 
ATOM   418  C C    . THR A 1 48  ? 16.83600 31.20100 0.16100   1.000 20.13662 ? 51  THR A C    1 
ATOM   419  O O    . THR A 1 48  ? 16.46300 32.35200 0.41700   1.000 22.30794 ? 51  THR A O    1 
ATOM   420  C CB   . THR A 1 48  ? 16.84900 30.28100 2.49500   1.000 17.74950 ? 51  THR A CB   1 
ATOM   421  O OG1  . THR A 1 48  ? 18.27100 30.40100 2.54000   1.000 17.59421 ? 51  THR A OG1  1 
ATOM   422  C CG2  . THR A 1 48  ? 16.36700 29.13200 3.39100   1.000 17.35734 ? 51  THR A CG2  1 
ATOM   423  H H    . THR A 1 48  ? 17.46700 28.39700 0.98200   1.000 19.07000 ? 51  THR A H    1 
ATOM   424  H HA   . THR A 1 48  ? 15.41800 30.05900 1.07000   1.000 20.89000 ? 51  THR A HA   1 
ATOM   425  H HB   . THR A 1 48  ? 16.46600 31.10200 2.84100   1.000 21.31000 ? 51  THR A HB   1 
ATOM   426  H HG1  . THR A 1 48  ? 18.62800 29.69500 2.25700   1.000 21.12000 ? 51  THR A HG1  1 
ATOM   427  H HG21 . THR A 1 48  ? 16.63500 29.29300 4.30900   1.000 20.84000 ? 51  THR A HG21 1 
ATOM   428  H HG22 . THR A 1 48  ? 15.40000 29.06500 3.35300   1.000 20.84000 ? 51  THR A HG22 1 
ATOM   429  H HG23 . THR A 1 48  ? 16.75300 28.29400 3.09200   1.000 20.84000 ? 51  THR A HG23 1 
ATOM   430  N N    . GLY A 1 49  ? 17.64200 30.92400 -0.85400  1.000 19.37338 ? 52  GLY A N    1 
ATOM   431  C CA   . GLY A 1 49  ? 18.05700 31.95600 -1.77700  1.000 22.06844 ? 52  GLY A CA   1 
ATOM   432  C C    . GLY A 1 49  ? 16.98600 32.20500 -2.80800  1.000 24.35818 ? 52  GLY A C    1 
ATOM   433  O O    . GLY A 1 49  ? 16.46200 33.31400 -2.92700  1.000 27.20589 ? 52  GLY A O    1 
ATOM   434  H H    . GLY A 1 49  ? 17.96000 30.14400 -1.02600  1.000 23.26000 ? 52  GLY A H    1 
ATOM   435  H HA2  . GLY A 1 49  ? 18.22600 32.78000 -1.29400  1.000 26.49000 ? 52  GLY A HA2  1 
ATOM   436  H HA3  . GLY A 1 49  ? 18.87100 31.68300 -2.22900  1.000 26.49000 ? 52  GLY A HA3  1 
ATOM   437  N N    . SER A 1 50  ? 16.63200 31.16100 -3.54300  1.000 24.41872 ? 53  SER A N    1 
ATOM   438  C CA   . SER A 1 50  ? 15.67100 31.29400 -4.62700  1.000 24.54505 ? 53  SER A CA   1 
ATOM   439  C C    . SER A 1 50  ? 14.24300 31.00100 -4.20100  1.000 25.49253 ? 53  SER A C    1 
ATOM   440  O O    . SER A 1 50  ? 13.30600 31.35000 -4.93000  1.000 27.53751 ? 53  SER A O    1 
ATOM   441  C CB   . SER A 1 50  ? 16.01900 30.29900 -5.72900  1.000 24.52662 ? 53  SER A CB   1 
ATOM   442  O OG   . SER A 1 50  ? 15.87200 28.97500 -5.24800  1.000 24.35292 ? 53  SER A OG   1 
ATOM   443  H H    . SER A 1 50  ? 16.93400 30.36400 -3.43400  1.000 29.31000 ? 53  SER A H    1 
ATOM   444  H HA   . SER A 1 50  ? 15.71700 32.20200 -4.96700  1.000 29.46000 ? 53  SER A HA   1 
ATOM   445  H HB2  . SER A 1 50  ? 15.42200 30.43300 -6.48100  1.000 29.44000 ? 53  SER A HB2  1 
ATOM   446  H HB3  . SER A 1 50  ? 16.93800 30.43700 -6.00600  1.000 29.44000 ? 53  SER A HB3  1 
ATOM   447  H HG   . SER A 1 50  ? 15.96200 28.42800 -5.87900  1.000 29.23000 ? 53  SER A HG   1 
ATOM   448  N N    . GLY A 1 51  ? 14.05200 30.36400 -3.05600  1.000 25.10301 ? 54  GLY A N    1 
ATOM   449  C CA   . GLY A 1 51  ? 12.74000 29.90400 -2.67500  1.000 25.87679 ? 54  GLY A CA   1 
ATOM   450  C C    . GLY A 1 51  ? 12.32600 28.60100 -3.30900  1.000 25.26092 ? 54  GLY A C    1 
ATOM   451  O O    . GLY A 1 51  ? 11.21600 28.12900 -3.03300  1.000 26.54002 ? 54  GLY A O    1 
ATOM   452  H H    . GLY A 1 51  ? 14.67100 30.18800 -2.48600  1.000 30.13000 ? 54  GLY A H    1 
ATOM   453  H HA2  . GLY A 1 51  ? 12.71800 29.78700 -1.71200  1.000 31.06000 ? 54  GLY A HA2  1 
ATOM   454  H HA3  . GLY A 1 51  ? 12.08800 30.57800 -2.92600  1.000 31.06000 ? 54  GLY A HA3  1 
ATOM   455  N N    . ALA A 1 52  ? 13.18200 27.98900 -4.12400  1.000 23.63704 ? 55  ALA A N    1 
ATOM   456  C CA   . ALA A 1 52  ? 12.87600 26.69200 -4.70700  1.000 22.58955 ? 55  ALA A CA   1 
ATOM   457  C C    . ALA A 1 52  ? 12.76000 25.63200 -3.62200  1.000 20.43403 ? 55  ALA A C    1 
ATOM   458  O O    . ALA A 1 52  ? 13.43400 25.69000 -2.58400  1.000 19.74974 ? 55  ALA A O    1 
ATOM   459  C CB   . ALA A 1 52  ? 13.98100 26.28300 -5.68400  1.000 23.82391 ? 55  ALA A CB   1 
ATOM   460  H H    . ALA A 1 52  ? 13.94800 28.30600 -4.35400  1.000 28.37000 ? 55  ALA A H    1 
ATOM   461  H HA   . ALA A 1 52  ? 12.03400 26.74600 -5.18500  1.000 27.11000 ? 55  ALA A HA   1 
ATOM   462  H HB1  . ALA A 1 52  ? 13.76700 25.41500 -6.05900  1.000 28.59000 ? 55  ALA A HB1  1 
ATOM   463  H HB2  . ALA A 1 52  ? 14.03700 26.94400 -6.39200  1.000 28.59000 ? 55  ALA A HB2  1 
ATOM   464  H HB3  . ALA A 1 52  ? 14.82400 26.23900 -5.20600  1.000 28.59000 ? 55  ALA A HB3  1 
ATOM   465  N N    . THR A 1 53  ? 11.92000 24.63200 -3.88500  1.000 19.88396 ? 56  THR A N    1 
ATOM   466  C CA   . THR A 1 53  ? 11.65100 23.58700 -2.91200  1.000 19.60498 ? 56  THR A CA   1 
ATOM   467  C C    . THR A 1 53  ? 11.65500 22.21600 -3.57700  1.000 18.77330 ? 56  THR A C    1 
ATOM   468  O O    . THR A 1 53  ? 11.42400 22.07100 -4.78800  1.000 20.91567 ? 56  THR A O    1 
ATOM   469  C CB   . THR A 1 53  ? 10.31300 23.79400 -2.16200  1.000 21.20254 ? 56  THR A CB   1 
ATOM   470  O OG1  . THR A 1 53  ? 9.24500  23.88200 -3.10600  1.000 23.00013 ? 56  THR A OG1  1 
ATOM   471  C CG2  . THR A 1 53  ? 10.34900 25.06800 -1.33400  1.000 21.65786 ? 56  THR A CG2  1 
ATOM   472  H H    . THR A 1 53  ? 11.49300 24.54100 -4.62500  1.000 23.87000 ? 56  THR A H    1 
ATOM   473  H HA   . THR A 1 53  ? 12.37300 23.60700 -2.26400  1.000 23.53000 ? 56  THR A HA   1 
ATOM   474  H HB   . THR A 1 53  ? 10.16200 23.04500 -1.56400  1.000 25.45000 ? 56  THR A HB   1 
ATOM   475  H HG1  . THR A 1 53  ? 9.20700  23.17800 -3.56200  1.000 27.61000 ? 56  THR A HG1  1 
ATOM   476  H HG21 . THR A 1 53  ? 9.50000  25.19500 -0.88200  1.000 26.00000 ? 56  THR A HG21 1 
ATOM   477  H HG22 . THR A 1 53  ? 11.05300 25.01300 -0.67000  1.000 26.00000 ? 56  THR A HG22 1 
ATOM   478  H HG23 . THR A 1 53  ? 10.51700 25.83200 -1.90800  1.000 26.00000 ? 56  THR A HG23 1 
ATOM   479  N N    . VAL A 1 54  ? 11.90900 21.20700 -2.74900  1.000 17.34418 ? 57  VAL A N    1 
ATOM   480  C CA   . VAL A 1 54  ? 11.69800 19.80400 -3.07800  1.000 16.30195 ? 57  VAL A CA   1 
ATOM   481  C C    . VAL A 1 54  ? 10.74000 19.24800 -2.03100  1.000 15.40185 ? 57  VAL A C    1 
ATOM   482  O O    . VAL A 1 54  ? 10.92700 19.47200 -0.82300  1.000 15.42553 ? 57  VAL A O    1 
ATOM   483  C CB   . VAL A 1 54  ? 13.02500 19.02100 -3.09700  1.000 16.59146 ? 57  VAL A CB   1 
ATOM   484  C CG1  . VAL A 1 54  ? 12.78500 17.52300 -3.09700  1.000 17.28628 ? 57  VAL A CG1  1 
ATOM   485  C CG2  . VAL A 1 54  ? 13.86500 19.44500 -4.31100  1.000 18.37852 ? 57  VAL A CG2  1 
ATOM   486  H H    . VAL A 1 54  ? 12.21900 21.31700 -1.95400  1.000 20.82000 ? 57  VAL A H    1 
ATOM   487  H HA   . VAL A 1 54  ? 11.29500 19.71500 -3.95600  1.000 19.57000 ? 57  VAL A HA   1 
ATOM   488  H HB   . VAL A 1 54  ? 13.52200 19.22900 -2.29000  1.000 19.92000 ? 57  VAL A HB   1 
ATOM   489  H HG11 . VAL A 1 54  ? 13.62200 17.06900 -3.28200  1.000 20.75000 ? 57  VAL A HG11 1 
ATOM   490  H HG12 . VAL A 1 54  ? 12.44900 17.25700 -2.22700  1.000 20.75000 ? 57  VAL A HG12 1 
ATOM   491  H HG13 . VAL A 1 54  ? 12.13300 17.30800 -3.78300  1.000 20.75000 ? 57  VAL A HG13 1 
ATOM   492  H HG21 . VAL A 1 54  ? 14.71600 18.98000 -4.28400  1.000 22.06000 ? 57  VAL A HG21 1 
ATOM   493  H HG22 . VAL A 1 54  ? 13.38700 19.21300 -5.12200  1.000 22.06000 ? 57  VAL A HG22 1 
ATOM   494  H HG23 . VAL A 1 54  ? 14.01000 20.40300 -4.27500  1.000 22.06000 ? 57  VAL A HG23 1 
ATOM   495  N N    . SER A 1 55  ? 9.70800  18.54700 -2.49900  1.000 14.35172 ? 59  SER A N    1 
ATOM   496  C CA   A SER A 1 55  ? 8.61900  18.10600 -1.64400  0.600 14.50437 ? 59  SER A CA   1 
ATOM   497  C CA   B SER A 1 55  ? 8.59900  18.10800 -1.65200  0.400 14.71229 ? 59  SER A CA   1 
ATOM   498  C C    . SER A 1 55  ? 8.21900  16.67800 -1.99400  1.000 15.60450 ? 59  SER A C    1 
ATOM   499  O O    . SER A 1 55  ? 7.93000  16.37500 -3.15400  1.000 18.10480 ? 59  SER A O    1 
ATOM   500  C CB   A SER A 1 55  ? 7.45800  19.08300 -1.84400  0.600 16.16246 ? 59  SER A CB   1 
ATOM   501  C CB   B SER A 1 55  ? 7.32200  18.94300 -1.85500  0.400 15.57818 ? 59  SER A CB   1 
ATOM   502  O OG   A SER A 1 55  ? 6.33500  18.74100 -1.10700  0.600 17.12574 ? 59  SER A OG   1 
ATOM   503  O OG   B SER A 1 55  ? 7.49000  20.30600 -1.55700  0.400 16.23879 ? 59  SER A OG   1 
ATOM   504  H H    A SER A 1 55  ? 9.61900  18.31300 -3.32100  0.600 17.23000 ? 59  SER A H    1 
ATOM   505  H H    B SER A 1 55  ? 9.62600  18.30700 -3.32100  0.400 17.23000 ? 59  SER A H    1 
ATOM   506  H HA   A SER A 1 55  ? 8.88000  18.07700 -0.71000  0.600 17.41000 ? 59  SER A HA   1 
ATOM   507  H HA   B SER A 1 55  ? 8.90900  18.18200 -0.73500  0.400 17.66000 ? 59  SER A HA   1 
ATOM   508  H HB2  A SER A 1 55  ? 7.74800  19.96700 -1.57100  0.600 19.40000 ? 59  SER A HB2  1 
ATOM   509  H HB2  B SER A 1 55  ? 7.05000  18.86500 -2.78300  0.400 18.70000 ? 59  SER A HB2  1 
ATOM   510  H HB3  A SER A 1 55  ? 7.21900  19.08900 -2.78500  0.600 19.40000 ? 59  SER A HB3  1 
ATOM   511  H HB3  B SER A 1 55  ? 6.62900  18.58700 -1.27500  0.400 18.70000 ? 59  SER A HB3  1 
ATOM   512  H HG   A SER A 1 55  ? 5.77200  19.36400 -1.13600  0.600 20.56000 ? 59  SER A HG   1 
ATOM   513  H HG   B SER A 1 55  ? 7.79200  20.39500 -0.77800  0.400 19.49000 ? 59  SER A HG   1 
ATOM   514  N N    . TYR A 1 56  ? 8.17400  15.80800 -0.98200  1.000 14.61491 ? 60  TYR A N    1 
ATOM   515  C CA   . TYR A 1 56  ? 7.73200  14.42800 -1.16000  1.000 14.23855 ? 60  TYR A CA   1 
ATOM   516  C C    . TYR A 1 56  ? 6.97700  14.03200 0.11000   1.000 13.52531 ? 60  TYR A C    1 
ATOM   517  O O    . TYR A 1 56  ? 7.56300  14.01200 1.19800   1.000 13.47530 ? 60  TYR A O    1 
ATOM   518  C CB   . TYR A 1 56  ? 8.89000  13.46600 -1.46700  1.000 15.22551 ? 60  TYR A CB   1 
ATOM   519  C CG   . TYR A 1 56  ? 8.41200  12.08800 -1.85300  1.000 16.07824 ? 60  TYR A CG   1 
ATOM   520  C CD1  . TYR A 1 56  ? 8.02900  11.80700 -3.16100  1.000 17.58895 ? 60  TYR A CD1  1 
ATOM   521  C CD2  . TYR A 1 56  ? 8.28600  11.07500 -0.91300  1.000 15.19656 ? 60  TYR A CD2  1 
ATOM   522  C CE1  . TYR A 1 56  ? 7.56400  10.57400 -3.50400  1.000 17.49157 ? 60  TYR A CE1  1 
ATOM   523  C CE2  . TYR A 1 56  ? 7.82300  9.83200  -1.25900  1.000 15.87822 ? 60  TYR A CE2  1 
ATOM   524  C CZ   . TYR A 1 56  ? 7.45900  9.58300  -2.56600  1.000 17.10731 ? 60  TYR A CZ   1 
ATOM   525  O OH   . TYR A 1 56  ? 7.00100  8.34800  -2.97600  1.000 18.96543 ? 60  TYR A OH   1 
ATOM   526  H H    . TYR A 1 56  ? 8.39800  15.99800 -0.17400  1.000 17.55000 ? 60  TYR A H    1 
ATOM   527  H HA   . TYR A 1 56  ? 7.13100  14.36600 -1.91900  1.000 17.09000 ? 60  TYR A HA   1 
ATOM   528  H HB2  . TYR A 1 56  ? 9.40900  13.82300 -2.20500  1.000 18.28000 ? 60  TYR A HB2  1 
ATOM   529  H HB3  . TYR A 1 56  ? 9.44800  13.38200 -0.67900  1.000 18.28000 ? 60  TYR A HB3  1 
ATOM   530  H HD1  . TYR A 1 56  ? 8.09200  12.47000 -3.81000  1.000 21.12000 ? 60  TYR A HD1  1 
ATOM   531  H HD2  . TYR A 1 56  ? 8.52000  11.24400 -0.02800  1.000 18.25000 ? 60  TYR A HD2  1 
ATOM   532  H HE1  . TYR A 1 56  ? 7.31400  10.40400 -4.38400  1.000 21.00000 ? 60  TYR A HE1  1 
ATOM   533  H HE2  . TYR A 1 56  ? 7.75500  9.16200  -0.61800  1.000 19.06000 ? 60  TYR A HE2  1 
ATOM   534  H HH   . TYR A 1 56  ? 6.96300  7.82400  -2.32000  1.000 22.76000 ? 60  TYR A HH   1 
ATOM   535  N N    . ARG A 1 57  ? 5.67700  13.76300 -0.01600  1.000 12.19357 ? 61  ARG A N    1 
ATOM   536  C CA   . ARG A 1 57  ? 4.82200  13.51200 1.14100   1.000 11.91722 ? 61  ARG A CA   1 
ATOM   537  C C    . ARG A 1 57  ? 4.94800  14.62600 2.17800   1.000 11.51191 ? 61  ARG A C    1 
ATOM   538  O O    . ARG A 1 57  ? 4.83000  14.39300 3.38600   1.000 12.04881 ? 61  ARG A O    1 
ATOM   539  C CB   . ARG A 1 57  ? 5.07800  12.14000 1.77400   1.000 11.93301 ? 61  ARG A CB   1 
ATOM   540  C CG   . ARG A 1 57  ? 4.87400  10.93400 0.87500   1.000 12.55677 ? 61  ARG A CG   1 
ATOM   541  C CD   . ARG A 1 57  ? 4.90600  9.63900  1.67800   1.000 14.28066 ? 61  ARG A CD   1 
ATOM   542  N NE   . ARG A 1 57  ? 4.83500  8.46000  0.82600   1.000 14.63070 ? 61  ARG A NE   1 
ATOM   543  C CZ   . ARG A 1 57  ? 3.72700  8.02800  0.24900   1.000 15.65977 ? 61  ARG A CZ   1 
ATOM   544  N NH1  . ARG A 1 57  ? 2.55600  8.59300  0.50300   1.000 16.14404 ? 61  ARG A NH1  1 
ATOM   545  N NH2  . ARG A 1 57  ? 3.79900  7.01100  -0.60700  1.000 17.50210 ? 61  ARG A NH2  1 
ATOM   546  H H    . ARG A 1 57  ? 5.26300  13.72100 -0.76900  1.000 14.64000 ? 61  ARG A H    1 
ATOM   547  H HA   . ARG A 1 57  ? 3.90500  13.50500 0.82600   1.000 14.31000 ? 61  ARG A HA   1 
ATOM   548  H HB2  . ARG A 1 57  ? 5.99800  12.11500 2.07900   1.000 14.33000 ? 61  ARG A HB2  1 
ATOM   549  H HB3  . ARG A 1 57  ? 4.47600  12.03900 2.52800   1.000 14.33000 ? 61  ARG A HB3  1 
ATOM   550  H HG2  . ARG A 1 57  ? 4.01100  11.00100 0.43600   1.000 15.08000 ? 61  ARG A HG2  1 
ATOM   551  H HG3  . ARG A 1 57  ? 5.58100  10.90200 0.21300   1.000 15.08000 ? 61  ARG A HG3  1 
ATOM   552  H HD2  . ARG A 1 57  ? 5.73400  9.59700  2.18200   1.000 17.14000 ? 61  ARG A HD2  1 
ATOM   553  H HD3  . ARG A 1 57  ? 4.14800  9.62000  2.28300   1.000 17.14000 ? 61  ARG A HD3  1 
ATOM   554  H HE   . ARG A 1 57  ? 5.55900  8.01700  0.68900   1.000 17.57000 ? 61  ARG A HE   1 
ATOM   555  H HH11 . ARG A 1 57  ? 2.50700  9.25400  1.05100   1.000 19.38000 ? 61  ARG A HH11 1 
ATOM   556  H HH12 . ARG A 1 57  ? 1.84500  8.29900  0.11900   1.000 19.38000 ? 61  ARG A HH12 1 
ATOM   557  H HH21 . ARG A 1 57  ? 4.55900  6.64600  -0.77800  1.000 21.01000 ? 61  ARG A HH21 1 
ATOM   558  H HH22 . ARG A 1 57  ? 3.08600  6.72000  -0.99000  1.000 21.01000 ? 61  ARG A HH22 1 
ATOM   559  N N    . ALA A 1 58  ? 5.12600  15.85500 1.72200   1.000 12.36464 ? 62  ALA A N    1 
ATOM   560  C CA   . ALA A 1 58  ? 5.56000  16.92700 2.60700   1.000 12.66204 ? 62  ALA A CA   1 
ATOM   561  C C    . ALA A 1 58  ? 4.48900  17.41200 3.55800   1.000 12.78311 ? 62  ALA A C    1 
ATOM   562  O O    . ALA A 1 58  ? 4.81700  18.03800 4.57800   1.000 12.56203 ? 62  ALA A O    1 
ATOM   563  C CB   . ALA A 1 58  ? 6.07100  18.11800 1.80900   1.000 13.26475 ? 62  ALA A CB   1 
ATOM   564  H H    . ALA A 1 58  ? 5.00300  16.09700 0.90600   1.000 14.84000 ? 62  ALA A H    1 
ATOM   565  H HA   . ALA A 1 58  ? 6.28800  16.56500 3.13600   1.000 15.20000 ? 62  ALA A HA   1 
ATOM   566  H HB1  . ALA A 1 58  ? 6.32700  18.82300 2.42300   1.000 15.93000 ? 62  ALA A HB1  1 
ATOM   567  H HB2  . ALA A 1 58  ? 6.83900  17.84100 1.28400   1.000 15.93000 ? 62  ALA A HB2  1 
ATOM   568  H HB3  . ALA A 1 58  ? 5.36500  18.43100 1.22200   1.000 15.93000 ? 62  ALA A HB3  1 
ATOM   569  N N    . GLU A 1 59  ? 3.22400  17.18800 3.23500   1.000 12.40938 ? 63  GLU A N    1 
ATOM   570  C CA   . GLU A 1 59  ? 2.12300  17.61200 4.08600   1.000 12.92260 ? 63  GLU A CA   1 
ATOM   571  C C    . GLU A 1 59  ? 1.51400  16.45800 4.87900   1.000 12.79627 ? 63  GLU A C    1 
ATOM   572  O O    . GLU A 1 59  ? 0.49900  16.65400 5.55400   1.000 14.84652 ? 63  GLU A O    1 
ATOM   573  C CB   . GLU A 1 59  ? 1.07100  18.35100 3.26100   1.000 14.30171 ? 63  GLU A CB   1 
ATOM   574  C CG   . GLU A 1 59  ? 1.57000  19.66600 2.65800   1.000 15.49396 ? 63  GLU A CG   1 
ATOM   575  C CD   . GLU A 1 59  ? 2.29300  19.48300 1.32600   1.000 15.67820 ? 63  GLU A CD   1 
ATOM   576  O OE1  . GLU A 1 59  ? 2.06600  18.43400 0.67000   1.000 15.37553 ? 63  GLU A OE1  1 
ATOM   577  O OE2  . GLU A 1 59  ? 3.05100  20.39000 0.93300   1.000 15.43869 ? 63  GLU A OE2  1 
ATOM   578  H H    . GLU A 1 59  ? 2.97400  16.78500 2.51700   1.000 14.90000 ? 63  GLU A H    1 
ATOM   579  H HA   . GLU A 1 59  ? 2.45700  18.24700 4.73900   1.000 15.51000 ? 63  GLU A HA   1 
ATOM   580  H HB2  . GLU A 1 59  ? 0.79000  17.77800 2.53000   1.000 17.17000 ? 63  GLU A HB2  1 
ATOM   581  H HB3  . GLU A 1 59  ? 0.31500  18.55600 3.83200   1.000 17.17000 ? 63  GLU A HB3  1 
ATOM   582  H HG2  . GLU A 1 59  ? 0.81100  20.25000 2.50600   1.000 18.60000 ? 63  GLU A HG2  1 
ATOM   583  H HG3  . GLU A 1 59  ? 2.19000  20.08100 3.27800   1.000 18.60000 ? 63  GLU A HG3  1 
ATOM   584  N N    . GLU A 1 60  ? 2.07700  15.26000 4.80700   1.000 12.27779 ? 64  GLU A N    1 
ATOM   585  C CA   . GLU A 1 60  ? 1.61800  14.18300 5.66200   1.000 12.48571 ? 64  GLU A CA   1 
ATOM   586  C C    . GLU A 1 60  ? 2.18900  14.35100 7.06300   1.000 12.82785 ? 64  GLU A C    1 
ATOM   587  O O    . GLU A 1 60  ? 3.25500  14.92800 7.25800   1.000 11.98828 ? 64  GLU A O    1 
ATOM   588  C CB   . GLU A 1 60  ? 2.04400  12.82000 5.13000   1.000 13.34897 ? 64  GLU A CB   1 
ATOM   589  C CG   . GLU A 1 60  ? 1.45700  12.47500 3.78100   1.000 13.79639 ? 64  GLU A CG   1 
ATOM   590  C CD   . GLU A 1 60  ? 1.80300  11.06600 3.32600   1.000 15.00443 ? 64  GLU A CD   1 
ATOM   591  O OE1  . GLU A 1 60  ? 1.99400  10.17400 4.17600   1.000 17.13627 ? 64  GLU A OE1  1 
ATOM   592  O OE2  . GLU A 1 60  ? 1.85800  10.82900 2.09900   1.000 14.46752 ? 64  GLU A OE2  1 
ATOM   593  H H    . GLU A 1 60  ? 2.72000  15.05000 4.27500   1.000 14.74000 ? 64  GLU A H    1 
ATOM   594  H HA   . GLU A 1 60  ? 0.64900  14.20600 5.69200   1.000 14.99000 ? 64  GLU A HA   1 
ATOM   595  H HB2  . GLU A 1 60  ? 3.01000  12.80800 5.04300   1.000 16.03000 ? 64  GLU A HB2  1 
ATOM   596  H HB3  . GLU A 1 60  ? 1.75900  12.13800 5.75800   1.000 16.03000 ? 64  GLU A HB3  1 
ATOM   597  H HG2  . GLU A 1 60  ? 0.49100  12.54500 3.83000   1.000 16.57000 ? 64  GLU A HG2  1 
ATOM   598  H HG3  . GLU A 1 60  ? 1.80200  13.09600 3.11900   1.000 16.57000 ? 64  GLU A HG3  1 
ATOM   599  N N    . ARG A 1 61  ? 1.45400  13.83600 8.04700   1.000 12.36990 ? 65  ARG A N    1 
ATOM   600  C CA   . ARG A 1 61  ? 1.94900  13.83900 9.42000   1.000 12.22515 ? 65  ARG A CA   1 
ATOM   601  C C    . ARG A 1 61  ? 2.85200  12.64500 9.68800   1.000 12.38306 ? 65  ARG A C    1 
ATOM   602  O O    . ARG A 1 61  ? 2.59000  11.51700 9.25300   1.000 12.19620 ? 65  ARG A O    1 
ATOM   603  C CB   . ARG A 1 61  ? 0.77700  13.83300 10.40200  1.000 12.33832 ? 65  ARG A CB   1 
ATOM   604  C CG   . ARG A 1 61  ? -0.00700 15.11100 10.41200  1.000 12.24884 ? 65  ARG A CG   1 
ATOM   605  C CD   . ARG A 1 61  ? -1.11400 15.14000 11.46500  1.000 13.38845 ? 65  ARG A CD   1 
ATOM   606  N NE   . ARG A 1 61  ? -1.67100 16.48200 11.61300  1.000 13.53320 ? 65  ARG A NE   1 
ATOM   607  C CZ   . ARG A 1 61  ? -1.10000 17.46800 12.29900  1.000 13.52267 ? 65  ARG A CZ   1 
ATOM   608  N NH1  . ARG A 1 61  ? -0.00100 17.27700 13.01500  1.000 12.60151 ? 65  ARG A NH1  1 
ATOM   609  N NH2  . ARG A 1 61  ? -1.63700 18.67800 12.26000  1.000 14.14380 ? 65  ARG A NH2  1 
ATOM   610  H H    . ARG A 1 61  ? 0.67700  13.48300 7.94600   1.000 14.85000 ? 65  ARG A H    1 
ATOM   611  H HA   . ARG A 1 61  ? 2.47400  14.64200 9.56200   1.000 14.68000 ? 65  ARG A HA   1 
ATOM   612  H HB2  . ARG A 1 61  ? 0.17100  13.11500 10.16100  1.000 14.82000 ? 65  ARG A HB2  1 
ATOM   613  H HB3  . ARG A 1 61  ? 1.12100  13.69000 11.29800  1.000 14.82000 ? 65  ARG A HB3  1 
ATOM   614  H HG2  . ARG A 1 61  ? 0.59600  15.84700 10.59500  1.000 14.71000 ? 65  ARG A HG2  1 
ATOM   615  H HG3  . ARG A 1 61  ? -0.42200 15.23000 9.54300   1.000 14.71000 ? 65  ARG A HG3  1 
ATOM   616  H HD2  . ARG A 1 61  ? -1.82800 14.54000 11.19900  1.000 16.07000 ? 65  ARG A HD2  1 
ATOM   617  H HD3  . ARG A 1 61  ? -0.75100 14.86400 12.32100  1.000 16.07000 ? 65  ARG A HD3  1 
ATOM   618  H HE   . ARG A 1 61  ? -2.42300 16.64600 11.22800  1.000 16.25000 ? 65  ARG A HE   1 
ATOM   619  H HH11 . ARG A 1 61  ? 0.36300  16.49900 13.04500  1.000 15.13000 ? 65  ARG A HH11 1 
ATOM   620  H HH12 . ARG A 1 61  ? 0.34900  17.93200 13.44900  1.000 15.13000 ? 65  ARG A HH12 1 
ATOM   621  H HH21 . ARG A 1 61  ? -2.34700 18.81900 11.79500  1.000 16.98000 ? 65  ARG A HH21 1 
ATOM   622  H HH22 . ARG A 1 61  ? -1.27600 19.32200 12.70000  1.000 16.98000 ? 65  ARG A HH22 1 
ATOM   623  N N    . PHE A 1 62  ? 3.92600  12.90700 10.43000  1.000 11.12239 ? 66  PHE A N    1 
ATOM   624  C CA   . PHE A 1 62  ? 4.83800  11.89600 10.91200  1.000 11.09344 ? 66  PHE A CA   1 
ATOM   625  C C    . PHE A 1 62  ? 5.10900  12.19000 12.37700  1.000 12.00933 ? 66  PHE A C    1 
ATOM   626  O O    . PHE A 1 62  ? 5.11400  13.35400 12.78300  1.000 11.66192 ? 66  PHE A O    1 
ATOM   627  C CB   . PHE A 1 62  ? 6.18400  11.97700 10.18300  1.000 11.16713 ? 66  PHE A CB   1 
ATOM   628  C CG   . PHE A 1 62  ? 6.13200  11.57800 8.71900   1.000 11.32241 ? 66  PHE A CG   1 
ATOM   629  C CD1  . PHE A 1 62  ? 5.64900  12.45300 7.75800   1.000 12.36727 ? 66  PHE A CD1  1 
ATOM   630  C CD2  . PHE A 1 62  ? 6.58800  10.33500 8.32500   1.000 12.18041 ? 66  PHE A CD2  1 
ATOM   631  C CE1  . PHE A 1 62  ? 5.63900  12.08200 6.40900   1.000 12.37780 ? 66  PHE A CE1  1 
ATOM   632  C CE2  . PHE A 1 62  ? 6.58100  9.95100  6.99200   1.000 12.19620 ? 66  PHE A CE2  1 
ATOM   633  C CZ   . PHE A 1 62  ? 6.10400  10.83600 6.02900   1.000 11.85142 ? 66  PHE A CZ   1 
ATOM   634  H H    . PHE A 1 62  ? 4.15100  13.70000 10.67300  1.000 13.35000 ? 66  PHE A H    1 
ATOM   635  H HA   . PHE A 1 62  ? 4.45900  11.01100 10.78900  1.000 13.32000 ? 66  PHE A HA   1 
ATOM   636  H HB2  . PHE A 1 62  ? 6.50300  12.89200 10.22500  1.000 13.41000 ? 66  PHE A HB2  1 
ATOM   637  H HB3  . PHE A 1 62  ? 6.81100  11.38500 10.62600  1.000 13.41000 ? 66  PHE A HB3  1 
ATOM   638  H HD1  . PHE A 1 62  ? 5.33100  13.28900 8.01200   1.000 14.85000 ? 66  PHE A HD1  1 
ATOM   639  H HD2  . PHE A 1 62  ? 6.90800  9.74300  8.96700   1.000 14.62000 ? 66  PHE A HD2  1 
ATOM   640  H HE1  . PHE A 1 62  ? 5.32000  12.67400 5.76800   1.000 14.86000 ? 66  PHE A HE1  1 
ATOM   641  H HE2  . PHE A 1 62  ? 6.89100  9.11000  6.74500   1.000 14.64000 ? 66  PHE A HE2  1 
ATOM   642  H HZ   . PHE A 1 62  ? 6.09800  10.58900 5.13200   1.000 14.23000 ? 66  PHE A HZ   1 
ATOM   643  N N    . PRO A 1 63  ? 5.34700  11.15700 13.18600  1.000 11.55928 ? 67  PRO A N    1 
ATOM   644  C CA   . PRO A 1 63  ? 5.70600  11.39100 14.59400  1.000 11.74615 ? 67  PRO A CA   1 
ATOM   645  C C    . PRO A 1 63  ? 6.97000  12.21700 14.73600  1.000 11.67508 ? 67  PRO A C    1 
ATOM   646  O O    . PRO A 1 63  ? 7.94900  12.01500 14.02800  1.000 11.88564 ? 67  PRO A O    1 
ATOM   647  C CB   . PRO A 1 63  ? 5.88100  9.97900  15.16200  1.000 11.86195 ? 67  PRO A CB   1 
ATOM   648  C CG   . PRO A 1 63  ? 5.04400  9.10000  14.25000  1.000 12.36464 ? 67  PRO A CG   1 
ATOM   649  C CD   . PRO A 1 63  ? 5.22500  9.72600  12.88400  1.000 12.57782 ? 67  PRO A CD   1 
ATOM   650  H HA   . PRO A 1 63  ? 4.98000  11.84200 15.05200  1.000 14.11000 ? 67  PRO A HA   1 
ATOM   651  H HB2  . PRO A 1 63  ? 6.81600  9.72300  15.13300  1.000 14.24000 ? 67  PRO A HB2  1 
ATOM   652  H HB3  . PRO A 1 63  ? 5.55600  9.94600  16.07500  1.000 14.24000 ? 67  PRO A HB3  1 
ATOM   653  H HG2  . PRO A 1 63  ? 5.37600  8.18800  14.26600  1.000 14.85000 ? 67  PRO A HG2  1 
ATOM   654  H HG3  . PRO A 1 63  ? 4.11400  9.11900  14.52600  1.000 14.85000 ? 67  PRO A HG3  1 
ATOM   655  H HD2  . PRO A 1 63  ? 6.02800  9.39300  12.45400  1.000 15.10000 ? 67  PRO A HD2  1 
ATOM   656  H HD3  . PRO A 1 63  ? 4.45300  9.55700  12.32100  1.000 15.10000 ? 67  PRO A HD3  1 
ATOM   657  N N    . LEU A 1 64  ? 6.93600  13.14200 15.68700  1.000 11.84353 ? 68  LEU A N    1 
ATOM   658  C CA   . LEU A 1 64  ? 8.10300  13.96100 15.97800  1.000 11.54612 ? 68  LEU A CA   1 
ATOM   659  C C    . LEU A 1 64  ? 9.20700  13.14800 16.64700  1.000 11.32767 ? 68  LEU A C    1 
ATOM   660  O O    . LEU A 1 64  ? 10.39300 13.40900 16.42600  1.000 11.73035 ? 68  LEU A O    1 
ATOM   661  C CB   . LEU A 1 64  ? 7.67400  15.11800 16.88300  1.000 12.32779 ? 68  LEU A CB   1 
ATOM   662  C CG   . LEU A 1 64  ? 6.84800  16.19900 16.18200  1.000 12.60414 ? 68  LEU A CG   1 
ATOM   663  C CD1  . LEU A 1 64  ? 6.07400  17.03700 17.19300  1.000 13.44635 ? 68  LEU A CD1  1 
ATOM   664  C CD2  . LEU A 1 64  ? 7.72400  17.08800 15.30200  1.000 12.94366 ? 68  LEU A CD2  1 
ATOM   665  H H    . LEU A 1 64  ? 6.25200  13.31500 16.17800  1.000 14.22000 ? 68  LEU A H    1 
ATOM   666  H HA   . LEU A 1 64  ? 8.46200  14.31600 15.15000  1.000 13.86000 ? 68  LEU A HA   1 
ATOM   667  H HB2  . LEU A 1 64  ? 7.13600  14.76000 17.60700  1.000 14.80000 ? 68  LEU A HB2  1 
ATOM   668  H HB3  . LEU A 1 64  ? 8.47000  15.54200 17.24000  1.000 14.80000 ? 68  LEU A HB3  1 
ATOM   669  H HG   . LEU A 1 64  ? 6.20600  15.75800 15.60400  1.000 15.13000 ? 68  LEU A HG   1 
ATOM   670  H HD11 . LEU A 1 64  ? 5.57400  17.72000 16.71900  1.000 16.15000 ? 68  LEU A HD11 1 
ATOM   671  H HD12 . LEU A 1 64  ? 5.46500  16.46100 17.68100  1.000 16.15000 ? 68  LEU A HD12 1 
ATOM   672  H HD13 . LEU A 1 64  ? 6.70100  17.45100 17.80600  1.000 16.15000 ? 68  LEU A HD13 1 
ATOM   673  H HD21 . LEU A 1 64  ? 7.16800  17.76600 14.88600  1.000 15.54000 ? 68  LEU A HD21 1 
ATOM   674  H HD22 . LEU A 1 64  ? 8.40100  17.50900 15.85400  1.000 15.54000 ? 68  LEU A HD22 1 
ATOM   675  H HD23 . LEU A 1 64  ? 8.14500  16.54200 14.62000  1.000 15.54000 ? 68  LEU A HD23 1 
ATOM   676  N N    . CYS A 1 65  ? 8.82700  12.19500 17.50700  1.000 11.96196 ? 69  CYS A N    1 
ATOM   677  C CA   . CYS A 1 65  ? 9.78000  11.53200 18.39200  1.000 12.22515 ? 69  CYS A CA   1 
ATOM   678  C C    . CYS A 1 65  ? 10.61700 12.60300 19.09900  1.000 12.64099 ? 69  CYS A C    1 
ATOM   679  O O    . CYS A 1 65  ? 10.10600 13.68100 19.42500  1.000 12.72784 ? 69  CYS A O    1 
ATOM   680  C CB   . CYS A 1 65  ? 10.63000 10.51500 17.62400  1.000 12.65152 ? 69  CYS A CB   1 
ATOM   681  S SG   . CYS A 1 65  ? 9.68800  9.51300  16.44000  1.000 12.44097 ? 69  CYS A SG   1 
ATOM   682  H H    . CYS A 1 65  ? 8.01800  11.91700 17.59400  1.000 14.36000 ? 69  CYS A H    1 
ATOM   683  H HA   . CYS A 1 65  ? 9.32200  11.01300 19.07200  1.000 14.68000 ? 69  CYS A HA   1 
ATOM   684  H HB2  . CYS A 1 65  ? 11.31400 10.99300 17.12900  1.000 15.19000 ? 69  CYS A HB2  1 
ATOM   685  H HB3  . CYS A 1 65  ? 11.04300 9.91100  18.26000  1.000 15.19000 ? 69  CYS A HB3  1 
ATOM   686  N N    . SER A 1 66  ? 11.91100 12.35100 19.29300  1.000 11.76457 ? 70  SER A N    1 
ATOM   687  C CA   . SER A 1 66  ? 12.70600 13.31700 20.04100  1.000 11.75930 ? 70  SER A CA   1 
ATOM   688  C C    . SER A 1 66  ? 12.93800 14.62700 19.30000  1.000 11.88037 ? 70  SER A C    1 
ATOM   689  O O    . SER A 1 66  ? 13.53000 15.54300 19.88000  1.000 12.56466 ? 70  SER A O    1 
ATOM   690  C CB   . SER A 1 66  ? 14.11300 12.80300 20.35100  1.000 12.57519 ? 70  SER A CB   1 
ATOM   691  O OG   . SER A 1 66  ? 14.11300 11.69600 21.28200  1.000 13.85692 ? 70  SER A OG   1 
ATOM   692  H H    . SER A 1 66  ? 12.33300 11.65600 19.01300  1.000 14.13000 ? 70  SER A H    1 
ATOM   693  H HA   . SER A 1 66  ? 12.20900 13.45400 20.86200  1.000 14.12000 ? 70  SER A HA   1 
ATOM   694  H HB2  . SER A 1 66  ? 14.52300 12.50800 19.52200  1.000 15.10000 ? 70  SER A HB2  1 
ATOM   695  H HB3  . SER A 1 66  ? 14.62800 13.52900 20.73600  1.000 15.10000 ? 70  SER A HB3  1 
ATOM   696  N N    . SER A 1 67  ? 12.54700 14.72900 18.02400  1.000 10.89604 ? 71  SER A N    1 
ATOM   697  C CA   . SER A 1 67  ? 12.83900 15.94800 17.28200  1.000 12.10935 ? 71  SER A CA   1 
ATOM   698  C C    . SER A 1 67  ? 12.07500 17.15200 17.82300  1.000 12.05408 ? 71  SER A C    1 
ATOM   699  O O    . SER A 1 67  ? 12.43900 18.28900 17.51500  1.000 12.42517 ? 71  SER A O    1 
ATOM   700  C CB   . SER A 1 67  ? 12.60000 15.77900 15.76900  1.000 11.81194 ? 71  SER A CB   1 
ATOM   701  O OG   . SER A 1 67  ? 11.21100 15.81500 15.43000  1.000 12.76469 ? 71  SER A OG   1 
ATOM   702  H H    . SER A 1 67  ? 12.12500 14.12300 17.58500  1.000 13.08000 ? 71  SER A H    1 
ATOM   703  H HA   . SER A 1 67  ? 13.78800 16.12900 17.37000  1.000 14.54000 ? 71  SER A HA   1 
ATOM   704  H HB2  . SER A 1 67  ? 13.05100 16.50000 15.30200  1.000 14.18000 ? 71  SER A HB2  1 
ATOM   705  H HB3  . SER A 1 67  ? 12.96400 14.92400 15.49100  1.000 14.18000 ? 71  SER A HB3  1 
ATOM   706  H HG   . SER A 1 67  ? 10.81500 15.15800 15.77300  1.000 15.32000 ? 71  SER A HG   1 
ATOM   707  N N    . PHE A 1 68  ? 11.05700 16.94200 18.66300  1.000 12.26989 ? 72  PHE A N    1 
ATOM   708  C CA   . PHE A 1 68  ? 10.39500 18.08400 19.27900  1.000 13.00156 ? 72  PHE A CA   1 
ATOM   709  C C    . PHE A 1 68  ? 11.35200 18.89800 20.13900  1.000 13.35686 ? 72  PHE A C    1 
ATOM   710  O O    . PHE A 1 68  ? 11.09600 20.08900 20.37100  1.000 13.47004 ? 72  PHE A O    1 
ATOM   711  C CB   . PHE A 1 68  ? 9.18300  17.66500 20.13100  1.000 13.11736 ? 72  PHE A CB   1 
ATOM   712  C CG   . PHE A 1 68  ? 9.53600  17.18300 21.54000  1.000 13.53847 ? 72  PHE A CG   1 
ATOM   713  C CD1  . PHE A 1 68  ? 9.81600  15.84000 21.79000  1.000 14.55701 ? 72  PHE A CD1  1 
ATOM   714  C CD2  . PHE A 1 68  ? 9.56800  18.06200 22.59600  1.000 14.25171 ? 72  PHE A CD2  1 
ATOM   715  C CE1  . PHE A 1 68  ? 10.15200 15.41200 23.06000  1.000 15.44396 ? 72  PHE A CE1  1 
ATOM   716  C CE2  . PHE A 1 68  ? 9.89300  17.63000 23.86900  1.000 15.29657 ? 72  PHE A CE2  1 
ATOM   717  C CZ   . PHE A 1 68  ? 10.16900 16.31700 24.10300  1.000 15.18603 ? 72  PHE A CZ   1 
ATOM   718  H H    . PHE A 1 68  ? 10.74300 16.17200 18.88200  1.000 14.73000 ? 72  PHE A H    1 
ATOM   719  H HA   . PHE A 1 68  ? 10.05400 18.63900 18.56000  1.000 15.61000 ? 72  PHE A HA   1 
ATOM   720  H HB2  . PHE A 1 68  ? 8.59000  18.42700 20.22100  1.000 15.74000 ? 72  PHE A HB2  1 
ATOM   721  H HB3  . PHE A 1 68  ? 8.72400  16.93900 19.68000  1.000 15.74000 ? 72  PHE A HB3  1 
ATOM   722  H HD1  . PHE A 1 68  ? 9.77600  15.22600 21.09400  1.000 17.48000 ? 72  PHE A HD1  1 
ATOM   723  H HD2  . PHE A 1 68  ? 9.36900  18.95900 22.45300  1.000 17.11000 ? 72  PHE A HD2  1 
ATOM   724  H HE1  . PHE A 1 68  ? 10.36400 14.52000 23.21100  1.000 18.54000 ? 72  PHE A HE1  1 
ATOM   725  H HE2  . PHE A 1 68  ? 9.92300  18.24000 24.57100  1.000 18.36000 ? 72  PHE A HE2  1 
ATOM   726  H HZ   . PHE A 1 68  ? 10.36900 16.03000 24.96400  1.000 18.23000 ? 72  PHE A HZ   1 
ATOM   727  N N    . LYS A 1 69  ? 12.46100 18.28900 20.59700  1.000 13.20421 ? 73  LYS A N    1 
ATOM   728  C CA   . LYS A 1 69  ? 13.33300 18.96100 21.55900  1.000 13.13842 ? 73  LYS A CA   1 
ATOM   729  C C    . LYS A 1 69  ? 14.05000 20.16200 20.95700  1.000 13.10420 ? 73  LYS A C    1 
ATOM   730  O O    . LYS A 1 69  ? 14.38600 21.10400 21.68100  1.000 13.48583 ? 73  LYS A O    1 
ATOM   731  C CB   . LYS A 1 69  ? 14.34600 17.98300 22.14200  1.000 13.61216 ? 73  LYS A CB   1 
ATOM   732  C CG   . LYS A 1 69  ? 13.75000 16.83100 22.91200  1.000 13.31212 ? 73  LYS A CG   1 
ATOM   733  C CD   . LYS A 1 69  ? 14.76000 15.76200 23.20400  1.000 14.26487 ? 73  LYS A CD   1 
ATOM   734  C CE   . LYS A 1 69  ? 14.13600 14.46800 23.67300  1.000 15.27552 ? 73  LYS A CE   1 
ATOM   735  N NZ   . LYS A 1 69  ? 15.04700 13.30300 23.77900  1.000 16.94414 ? 73  LYS A NZ   1 
ATOM   736  H H    . LYS A 1 69  ? 12.72000 17.50100 20.36800  1.000 15.85000 ? 73  LYS A H    1 
ATOM   737  H HA   . LYS A 1 69  ? 12.77600 19.28400 22.28500  1.000 15.78000 ? 73  LYS A HA   1 
ATOM   738  H HB2  . LYS A 1 69  ? 14.86500 17.60800 21.41400  1.000 16.34000 ? 73  LYS A HB2  1 
ATOM   739  H HB3  . LYS A 1 69  ? 14.92700 18.46800 22.74900  1.000 16.34000 ? 73  LYS A HB3  1 
ATOM   740  H HG2  . LYS A 1 69  ? 13.40300 17.15800 23.75700  1.000 15.98000 ? 73  LYS A HG2  1 
ATOM   741  H HG3  . LYS A 1 69  ? 13.03400 16.43500 22.39100  1.000 15.98000 ? 73  LYS A HG3  1 
ATOM   742  H HD2  . LYS A 1 69  ? 15.26300 15.57500 22.39700  1.000 17.13000 ? 73  LYS A HD2  1 
ATOM   743  H HD3  . LYS A 1 69  ? 15.35700 16.07500 23.90200  1.000 17.13000 ? 73  LYS A HD3  1 
ATOM   744  H HE2  . LYS A 1 69  ? 13.75900 14.61500 24.55400  1.000 18.34000 ? 73  LYS A HE2  1 
ATOM   745  H HE3  . LYS A 1 69  ? 13.43500 14.22600 23.04800  1.000 18.34000 ? 73  LYS A HE3  1 
ATOM   746  H HZ1  . LYS A 1 69  ? 14.59000 12.58100 24.03000  1.000 20.34000 ? 73  LYS A HZ1  1 
ATOM   747  H HZ2  . LYS A 1 69  ? 15.42900 13.14300 22.99200  1.000 20.34000 ? 73  LYS A HZ2  1 
ATOM   748  H HZ3  . LYS A 1 69  ? 15.68200 13.46700 24.38100  1.000 20.34000 ? 73  LYS A HZ3  1 
ATOM   749  N N    . GLY A 1 70  ? 14.32100 20.15000 19.65200  1.000 12.81996 ? 74  GLY A N    1 
ATOM   750  C CA   . GLY A 1 70  ? 14.85400 21.35200 19.03300  1.000 12.44097 ? 74  GLY A CA   1 
ATOM   751  C C    . GLY A 1 70  ? 13.91600 22.53900 19.18200  1.000 13.20948 ? 74  GLY A C    1 
ATOM   752  O O    . GLY A 1 70  ? 14.32400 23.63900 19.56200  1.000 13.54636 ? 74  GLY A O    1 
ATOM   753  H H    . GLY A 1 70  ? 14.20800 19.48100 19.12300  1.000 15.39000 ? 74  GLY A H    1 
ATOM   754  H HA2  . GLY A 1 70  ? 15.70200 21.57800 19.44600  1.000 14.94000 ? 74  GLY A HA2  1 
ATOM   755  H HA3  . GLY A 1 70  ? 14.99700 21.19100 18.08700  1.000 14.94000 ? 74  GLY A HA3  1 
ATOM   756  N N    . PHE A 1 71  ? 12.63200 22.33000 18.86200  1.000 13.20158 ? 75  PHE A N    1 
ATOM   757  C CA   . PHE A 1 71  ? 11.65700 23.40600 18.99300  1.000 14.12801 ? 75  PHE A CA   1 
ATOM   758  C C    . PHE A 1 71  ? 11.45600 23.80900 20.44800  1.000 13.96483 ? 75  PHE A C    1 
ATOM   759  O O    . PHE A 1 71  ? 11.23200 24.98600 20.73600  1.000 14.65176 ? 75  PHE A O    1 
ATOM   760  C CB   . PHE A 1 71  ? 10.36000 22.98600 18.31300  1.000 13.99115 ? 75  PHE A CB   1 
ATOM   761  C CG   . PHE A 1 71  ? 10.51600 22.79800 16.83400  1.000 12.29621 ? 75  PHE A CG   1 
ATOM   762  C CD1  . PHE A 1 71  ? 10.91900 23.86400 16.04700  1.000 12.61730 ? 75  PHE A CD1  1 
ATOM   763  C CD2  . PHE A 1 71  ? 10.30200 21.56800 16.25100  1.000 12.42781 ? 75  PHE A CD2  1 
ATOM   764  C CE1  . PHE A 1 71  ? 11.07500 23.71100 14.68200  1.000 13.39897 ? 75  PHE A CE1  1 
ATOM   765  C CE2  . PHE A 1 71  ? 10.45900 21.40700 14.87000  1.000 12.76732 ? 75  PHE A CE2  1 
ATOM   766  C CZ   . PHE A 1 71  ? 10.84900 22.48400 14.09900  1.000 12.50413 ? 75  PHE A CZ   1 
ATOM   767  H H    . PHE A 1 71  ? 12.31000 21.58700 18.57300  1.000 15.85000 ? 75  PHE A H    1 
ATOM   768  H HA   . PHE A 1 71  ? 11.97100 24.20400 18.53800  1.000 16.96000 ? 75  PHE A HA   1 
ATOM   769  H HB2  . PHE A 1 71  ? 10.06300 22.14400 18.69300  1.000 16.80000 ? 75  PHE A HB2  1 
ATOM   770  H HB3  . PHE A 1 71  ? 9.69000  23.67100 18.46000  1.000 16.80000 ? 75  PHE A HB3  1 
ATOM   771  H HD1  . PHE A 1 71  ? 11.08500 24.69000 16.44100  1.000 15.15000 ? 75  PHE A HD1  1 
ATOM   772  H HD2  . PHE A 1 71  ? 10.05300 20.84300 16.77700  1.000 14.92000 ? 75  PHE A HD2  1 
ATOM   773  H HE1  . PHE A 1 71  ? 11.33200 24.43500 14.15800  1.000 16.09000 ? 75  PHE A HE1  1 
ATOM   774  H HE2  . PHE A 1 71  ? 10.30200 20.58000 14.47400  1.000 15.33000 ? 75  PHE A HE2  1 
ATOM   775  H HZ   . PHE A 1 71  ? 10.96000 22.38000 13.18200  1.000 15.01000 ? 75  PHE A HZ   1 
ATOM   776  N N    . LEU A 1 72  ? 11.56300 22.85100 21.36900  1.000 13.82008 ? 76  LEU A N    1 
ATOM   777  C CA   . LEU A 1 72  ? 11.53900 23.14900 22.79700  1.000 14.01747 ? 76  LEU A CA   1 
ATOM   778  C C    . LEU A 1 72  ? 12.64600 24.11400 23.18100  1.000 13.46477 ? 76  LEU A C    1 
ATOM   779  O O    . LEU A 1 72  ? 12.40800 25.09100 23.90200  1.000 14.19381 ? 76  LEU A O    1 
ATOM   780  C CB   . LEU A 1 72  ? 11.65500 21.84000 23.57000  1.000 15.22025 ? 76  LEU A CB   1 
ATOM   781  C CG   . LEU A 1 72  ? 11.66400 21.92000 25.09700  1.000 17.32839 ? 76  LEU A CG   1 
ATOM   782  C CD1  . LEU A 1 72  ? 10.37700 22.51000 25.62100  1.000 18.15744 ? 76  LEU A CD1  1 
ATOM   783  C CD2  . LEU A 1 72  ? 11.88600 20.52400 25.64800  1.000 19.19967 ? 76  LEU A CD2  1 
ATOM   784  H H    . LEU A 1 72  ? 11.65000 22.01400 21.19000  1.000 16.59000 ? 76  LEU A H    1 
ATOM   785  H HA   . LEU A 1 72  ? 10.70000 23.57600 23.02800  1.000 16.83000 ? 76  LEU A HA   1 
ATOM   786  H HB2  . LEU A 1 72  ? 10.90100 21.28200 23.32200  1.000 18.27000 ? 76  LEU A HB2  1 
ATOM   787  H HB3  . LEU A 1 72  ? 12.48500 21.41200 23.30600  1.000 18.27000 ? 76  LEU A HB3  1 
ATOM   788  H HG   . LEU A 1 72  ? 12.37800 22.50400 25.39700  1.000 20.81000 ? 76  LEU A HG   1 
ATOM   789  H HD11 . LEU A 1 72  ? 10.51600 22.81200 26.53200  1.000 21.80000 ? 76  LEU A HD11 1 
ATOM   790  H HD12 . LEU A 1 72  ? 10.12200 23.25900 25.06000  1.000 21.80000 ? 76  LEU A HD12 1 
ATOM   791  H HD13 . LEU A 1 72  ? 9.68600  21.83000 25.59900  1.000 21.80000 ? 76  LEU A HD13 1 
ATOM   792  H HD21 . LEU A 1 72  ? 11.85500 20.55800 26.61700  1.000 23.05000 ? 76  LEU A HD21 1 
ATOM   793  H HD22 . LEU A 1 72  ? 11.18700 19.93800 25.31600  1.000 23.05000 ? 76  LEU A HD22 1 
ATOM   794  H HD23 . LEU A 1 72  ? 12.75300 20.20300 25.35600  1.000 23.05000 ? 76  LEU A HD23 1 
ATOM   795  N N    . ALA A 1 73  ? 13.86800 23.85300 22.71800  1.000 13.87798 ? 77  ALA A N    1 
ATOM   796  C CA   . ALA A 1 73  ? 14.96700 24.75600 23.04500  1.000 14.71229 ? 77  ALA A CA   1 
ATOM   797  C C    . ALA A 1 73  ? 14.74900 26.13800 22.44400  1.000 14.34119 ? 77  ALA A C    1 
ATOM   798  O O    . ALA A 1 73  ? 15.08100 27.15400 23.06600  1.000 15.51239 ? 77  ALA A O    1 
ATOM   799  C CB   . ALA A 1 73  ? 16.28900 24.16200 22.58500  1.000 15.00969 ? 77  ALA A CB   1 
ATOM   800  H H    . ALA A 1 73  ? 14.08100 23.18000 22.22700  1.000 16.66000 ? 77  ALA A H    1 
ATOM   801  H HA   . ALA A 1 73  ? 15.00900 24.85900 24.00900  1.000 17.66000 ? 77  ALA A HA   1 
ATOM   802  H HB1  . ALA A 1 73  ? 17.00800 24.76700 22.82600  1.000 18.02000 ? 77  ALA A HB1  1 
ATOM   803  H HB2  . ALA A 1 73  ? 16.41800 23.30400 23.02000  1.000 18.02000 ? 77  ALA A HB2  1 
ATOM   804  H HB3  . ALA A 1 73  ? 16.26400 24.04400 21.62300  1.000 18.02000 ? 77  ALA A HB3  1 
ATOM   805  N N    . ALA A 1 74  ? 14.15700 26.20100 21.24600  1.000 14.50174 ? 78  ALA A N    1 
ATOM   806  C CA   . ALA A 1 74  ? 13.82600 27.49900 20.66900  1.000 15.01496 ? 78  ALA A CA   1 
ATOM   807  C C    . ALA A 1 74  ? 12.78900 28.23900 21.50900  1.000 15.65977 ? 78  ALA A C    1 
ATOM   808  O O    . ALA A 1 74  ? 12.88700 29.45800 21.68300  1.000 15.90454 ? 78  ALA A O    1 
ATOM   809  C CB   . ALA A 1 74  ? 13.31300 27.32200 19.23400  1.000 14.97285 ? 78  ALA A CB   1 
ATOM   810  H H    . ALA A 1 74  ? 13.94400 25.52200 20.76300  1.000 17.41000 ? 78  ALA A H    1 
ATOM   811  H HA   . ALA A 1 74  ? 14.63200 28.03700 20.64200  1.000 18.02000 ? 78  ALA A HA   1 
ATOM   812  H HB1  . ALA A 1 74  ? 13.11900 28.19500 18.85800  1.000 17.98000 ? 78  ALA A HB1  1 
ATOM   813  H HB2  . ALA A 1 74  ? 13.99600 26.87900 18.70700  1.000 17.98000 ? 78  ALA A HB2  1 
ATOM   814  H HB3  . ALA A 1 74  ? 12.50700 26.78200 19.25100  1.000 17.98000 ? 78  ALA A HB3  1 
ATOM   815  N N    . ALA A 1 75  ? 11.78900 27.52000 22.02800  1.000 15.11234 ? 79  ALA A N    1 
ATOM   816  C CA   . ALA A 1 75  ? 10.77400 28.14400 22.86800  1.000 15.42027 ? 79  ALA A CA   1 
ATOM   817  C C    . ALA A 1 75  ? 11.37900 28.67500 24.15300  1.000 15.24920 ? 79  ALA A C    1 
ATOM   818  O O    . ALA A 1 75  ? 10.99600 29.75000 24.63100  1.000 16.29932 ? 79  ALA A O    1 
ATOM   819  C CB   . ALA A 1 75  ? 9.68000  27.13500 23.18000  1.000 15.64398 ? 79  ALA A CB   1 
ATOM   820  H H    . ALA A 1 75  ? 11.68000 26.67500 21.90900  1.000 18.14000 ? 79  ALA A H    1 
ATOM   821  H HA   . ALA A 1 75  ? 10.37900 28.88900 22.38800  1.000 18.51000 ? 79  ALA A HA   1 
ATOM   822  H HB1  . ALA A 1 75  ? 9.00700  27.56000 23.73400  1.000 18.78000 ? 79  ALA A HB1  1 
ATOM   823  H HB2  . ALA A 1 75  ? 9.28100  26.83500 22.34800  1.000 18.78000 ? 79  ALA A HB2  1 
ATOM   824  H HB3  . ALA A 1 75  ? 10.07000 26.38200 23.65100  1.000 18.78000 ? 79  ALA A HB3  1 
ATOM   825  N N    . VAL A 1 76  ? 12.34600 27.94600 24.71000  1.000 15.18866 ? 80  VAL A N    1 
ATOM   826  C CA   . VAL A 1 76  ? 13.06200 28.43500 25.88800  1.000 16.34933 ? 80  VAL A CA   1 
ATOM   827  C C    . VAL A 1 76  ? 13.79200 29.72300 25.54500  1.000 15.79137 ? 80  VAL A C    1 
ATOM   828  O O    . VAL A 1 76  ? 13.74900 30.70800 26.28600  1.000 16.49671 ? 80  VAL A O    1 
ATOM   829  C CB   . VAL A 1 76  ? 14.03600 27.36200 26.40800  1.000 17.28628 ? 80  VAL A CB   1 
ATOM   830  C CG1  . VAL A 1 76  ? 14.94200 27.92800 27.50500  1.000 18.72330 ? 80  VAL A CG1  1 
ATOM   831  C CG2  . VAL A 1 76  ? 13.28200 26.13100 26.91100  1.000 17.53894 ? 80  VAL A CG2  1 
ATOM   832  H H    . VAL A 1 76  ? 12.60300 27.17500 24.42900  1.000 18.24000 ? 80  VAL A H    1 
ATOM   833  H HA   . VAL A 1 76  ? 12.42000 28.62100 26.59100  1.000 19.63000 ? 80  VAL A HA   1 
ATOM   834  H HB   . VAL A 1 76  ? 14.60000 27.08300 25.66900  1.000 20.75000 ? 80  VAL A HB   1 
ATOM   835  H HG11 . VAL A 1 76  ? 15.40600 27.19600 27.94000  1.000 22.47000 ? 80  VAL A HG11 1 
ATOM   836  H HG12 . VAL A 1 76  ? 15.58300 28.53500 27.10400  1.000 22.47000 ? 80  VAL A HG12 1 
ATOM   837  H HG13 . VAL A 1 76  ? 14.39600 28.40300 28.15100  1.000 22.47000 ? 80  VAL A HG13 1 
ATOM   838  H HG21 . VAL A 1 76  ? 13.92400 25.44700 27.15800  1.000 21.05000 ? 80  VAL A HG21 1 
ATOM   839  H HG22 . VAL A 1 76  ? 12.75000 26.38000 27.68200  1.000 21.05000 ? 80  VAL A HG22 1 
ATOM   840  H HG23 . VAL A 1 76  ? 12.70600 25.80300 26.20300  1.000 21.05000 ? 80  VAL A HG23 1 
ATOM   841  N N    . LEU A 1 77  ? 14.49000 29.73200 24.40700  1.000 15.94665 ? 81  LEU A N    1 
ATOM   842  C CA   . LEU A 1 77  ? 15.20600 30.93500 24.00200  1.000 16.71253 ? 81  LEU A CA   1 
ATOM   843  C C    . LEU A 1 77  ? 14.25400 32.10600 23.79400  1.000 16.95203 ? 81  LEU A C    1 
ATOM   844  O O    . LEU A 1 77  ? 14.56000 33.23800 24.17800  1.000 17.42841 ? 81  LEU A O    1 
ATOM   845  C CB   . LEU A 1 77  ? 16.03700 30.65200 22.75200  1.000 16.33617 ? 81  LEU A CB   1 
ATOM   846  C CG   . LEU A 1 77  ? 17.29600 29.82000 22.98300  1.000 15.37290 ? 81  LEU A CG   1 
ATOM   847  C CD1  . LEU A 1 77  ? 17.78700 29.29400 21.62700  1.000 15.55713 ? 81  LEU A CD1  1 
ATOM   848  C CD2  . LEU A 1 77  ? 18.36400 30.63700 23.65900  1.000 16.47566 ? 81  LEU A CD2  1 
ATOM   849  H H    . LEU A 1 77  ? 14.56100 29.06800 23.86500  1.000 19.14000 ? 81  LEU A H    1 
ATOM   850  H HA   . LEU A 1 77  ? 15.82200 31.19100 24.70700  1.000 20.06000 ? 81  LEU A HA   1 
ATOM   851  H HB2  . LEU A 1 77  ? 15.48100 30.17100 22.11900  1.000 19.61000 ? 81  LEU A HB2  1 
ATOM   852  H HB3  . LEU A 1 77  ? 16.31400 31.50000 22.37100  1.000 19.61000 ? 81  LEU A HB3  1 
ATOM   853  H HG   . LEU A 1 77  ? 17.09900 29.07100 23.56800  1.000 18.45000 ? 81  LEU A HG   1 
ATOM   854  H HD11 . LEU A 1 77  ? 18.61900 28.81200 21.75700  1.000 18.68000 ? 81  LEU A HD11 1 
ATOM   855  H HD12 . LEU A 1 77  ? 17.11600 28.70100 21.25600  1.000 18.68000 ? 81  LEU A HD12 1 
ATOM   856  H HD13 . LEU A 1 77  ? 17.93100 30.04500 21.03000  1.000 18.68000 ? 81  LEU A HD13 1 
ATOM   857  H HD21 . LEU A 1 77  ? 19.18500 30.12100 23.68700  1.000 19.78000 ? 81  LEU A HD21 1 
ATOM   858  H HD22 . LEU A 1 77  ? 18.50300 31.45400 23.15500  1.000 19.78000 ? 81  LEU A HD22 1 
ATOM   859  H HD23 . LEU A 1 77  ? 18.07600 30.84900 24.56100  1.000 19.78000 ? 81  LEU A HD23 1 
ATOM   860  N N    . ALA A 1 78  ? 13.09000 31.86000 23.18900  1.000 17.41261 ? 82  ALA A N    1 
ATOM   861  C CA   . ALA A 1 78  ? 12.11600 32.93200 23.02000  1.000 17.69159 ? 82  ALA A CA   1 
ATOM   862  C C    . ALA A 1 78  ? 11.71000 33.51000 24.36800  1.000 18.81278 ? 82  ALA A C    1 
ATOM   863  O O    . ALA A 1 78  ? 11.66400 34.73200 24.54700  1.000 19.20757 ? 82  ALA A O    1 
ATOM   864  C CB   . ALA A 1 78  ? 10.89800 32.40100 22.26400  1.000 18.69171 ? 82  ALA A CB   1 
ATOM   865  H H    . ALA A 1 78  ? 12.84800 31.09800 22.87500  1.000 20.90000 ? 82  ALA A H    1 
ATOM   866  H HA   . ALA A 1 78  ? 12.51000 33.64600 22.49500  1.000 21.24000 ? 82  ALA A HA   1 
ATOM   867  H HB1  . ALA A 1 78  ? 10.26300 33.12400 22.14300  1.000 22.44000 ? 82  ALA A HB1  1 
ATOM   868  H HB2  . ALA A 1 78  ? 11.18500 32.06400 21.40100  1.000 22.44000 ? 82  ALA A HB2  1 
ATOM   869  H HB3  . ALA A 1 78  ? 10.49300 31.68700 22.78100  1.000 22.44000 ? 82  ALA A HB3  1 
ATOM   870  N N    . ARG A 1 79  ? 11.42600 32.64100 25.33800  1.000 19.62604 ? 83  ARG A N    1 
ATOM   871  C CA   . ARG A 1 79  ? 11.06400 33.12600 26.66300  1.000 21.43941 ? 83  ARG A CA   1 
ATOM   872  C C    . ARG A 1 79  ? 12.20100 33.93000 27.26700  1.000 21.89473 ? 83  ARG A C    1 
ATOM   873  O O    . ARG A 1 79  ? 11.96700 34.92300 27.96400  1.000 22.87906 ? 83  ARG A O    1 
ATOM   874  C CB   . ARG A 1 79  ? 10.70700 31.94800 27.56600  1.000 23.52124 ? 83  ARG A CB   1 
ATOM   875  C CG   . ARG A 1 79  ? 10.29700 32.39600 28.96500  1.000 26.92428 ? 83  ARG A CG   1 
ATOM   876  C CD   . ARG A 1 79  ? 9.73100  31.27100 29.80100  1.000 31.21690 ? 83  ARG A CD   1 
ATOM   877  N NE   . ARG A 1 79  ? 8.44600  30.80900 29.29400  1.000 34.04619 ? 83  ARG A NE   1 
ATOM   878  C CZ   . ARG A 1 79  ? 7.70000  29.88400 29.88600  1.000 36.01484 ? 83  ARG A CZ   1 
ATOM   879  N NH1  . ARG A 1 79  ? 8.08300  29.30400 31.01400  1.000 37.14919 ? 83  ARG A NH1  1 
ATOM   880  N NH2  . ARG A 1 79  ? 6.54800  29.52700 29.32800  1.000 35.89641 ? 83  ARG A NH2  1 
ATOM   881  H H    . ARG A 1 79  ? 11.43500 31.78500 25.25500  1.000 23.56000 ? 83  ARG A H    1 
ATOM   882  H HA   . ARG A 1 79  ? 10.28500 33.70000 26.59400  1.000 25.74000 ? 83  ARG A HA   1 
ATOM   883  H HB2  . ARG A 1 79  ? 9.96400  31.46100 27.17500  1.000 28.24000 ? 83  ARG A HB2  1 
ATOM   884  H HB3  . ARG A 1 79  ? 11.47800 31.36500 27.64900  1.000 28.24000 ? 83  ARG A HB3  1 
ATOM   885  H HG2  . ARG A 1 79  ? 11.07600 32.74700 29.42500  1.000 32.32000 ? 83  ARG A HG2  1 
ATOM   886  H HG3  . ARG A 1 79  ? 9.61800  33.08400 28.89000  1.000 32.32000 ? 83  ARG A HG3  1 
ATOM   887  H HD2  . ARG A 1 79  ? 10.34800 30.52300 29.78900  1.000 37.47000 ? 83  ARG A HD2  1 
ATOM   888  H HD3  . ARG A 1 79  ? 9.60400  31.58200 30.71100  1.000 37.47000 ? 83  ARG A HD3  1 
ATOM   889  H HE   . ARG A 1 79  ? 8.15100  31.15700 28.56500  1.000 40.86000 ? 83  ARG A HE   1 
ATOM   890  H HH11 . ARG A 1 79  ? 8.83000  29.52400 31.37900  1.000 44.58000 ? 83  ARG A HH11 1 
ATOM   891  H HH12 . ARG A 1 79  ? 7.58500  28.70700 31.38100  1.000 44.58000 ? 83  ARG A HH12 1 
ATOM   892  H HH21 . ARG A 1 79  ? 6.29400  29.89400 28.59300  1.000 43.08000 ? 83  ARG A HH21 1 
ATOM   893  H HH22 . ARG A 1 79  ? 6.05600  28.92900 29.70200  1.000 43.08000 ? 83  ARG A HH22 1 
ATOM   894  N N    . SER A 1 80  ? 13.44200 33.51900 27.00500  1.000 20.51035 ? 84  SER A N    1 
ATOM   895  C CA   . SER A 1 80  ? 14.59100 34.19900 27.59700  1.000 21.14990 ? 84  SER A CA   1 
ATOM   896  C C    . SER A 1 80  ? 14.72200 35.62700 27.09800  1.000 23.04224 ? 84  SER A C    1 
ATOM   897  O O    . SER A 1 80  ? 15.41400 36.43400 27.72600  1.000 24.37661 ? 84  SER A O    1 
ATOM   898  C CB   . SER A 1 80  ? 15.88000 33.41300 27.31800  1.000 21.58417 ? 84  SER A CB   1 
ATOM   899  O OG   . SER A 1 80  ? 16.41600 33.68700 26.02900  1.000 22.45269 ? 84  SER A OG   1 
ATOM   900  H H    . SER A 1 80  ? 13.64300 32.85700 26.49400  1.000 24.62000 ? 84  SER A H    1 
ATOM   901  H HA   . SER A 1 80  ? 14.47600 34.23000 28.56000  1.000 25.39000 ? 84  SER A HA   1 
ATOM   902  H HB2  . SER A 1 80  ? 16.54000 33.65500 27.98600  1.000 25.91000 ? 84  SER A HB2  1 
ATOM   903  H HB3  . SER A 1 80  ? 15.68200 32.46500 27.37500  1.000 25.91000 ? 84  SER A HB3  1 
ATOM   904  H HG   . SER A 1 80  ? 15.83400 33.54500 25.43900  1.000 26.95000 ? 84  SER A HG   1 
ATOM   905  N N    . GLN A 1 81  ? 14.06800 35.95900 25.98500  1.000 24.17395 ? 85  GLN A N    1 
ATOM   906  C CA   . GLN A 1 81  ? 14.03900 37.34300 25.53400  1.000 25.84257 ? 85  GLN A CA   1 
ATOM   907  C C    . GLN A 1 81  ? 13.28300 38.22500 26.51600  1.000 28.34287 ? 85  GLN A C    1 
ATOM   908  O O    . GLN A 1 81  ? 13.64000 39.39300 26.68400  1.000 29.69567 ? 85  GLN A O    1 
ATOM   909  C CB   . GLN A 1 81  ? 13.43600 37.42000 24.13000  1.000 25.33198 ? 85  GLN A CB   1 
ATOM   910  C CG   . GLN A 1 81  ? 14.27200 36.68600 23.08400  1.000 25.97943 ? 85  GLN A CG   1 
ATOM   911  C CD   . GLN A 1 81  ? 13.62800 36.61100 21.71000  1.000 26.66899 ? 85  GLN A CD   1 
ATOM   912  O OE1  . GLN A 1 81  ? 14.01200 35.78600 20.89100  1.000 26.85585 ? 85  GLN A OE1  1 
ATOM   913  N NE2  . GLN A 1 81  ? 12.65300 37.47100 21.45400  1.000 28.07968 ? 85  GLN A NE2  1 
ATOM   914  H H    . GLN A 1 81  ? 13.64000 35.40900 25.48200  1.000 29.01000 ? 85  GLN A H    1 
ATOM   915  H HA   . GLN A 1 81  ? 14.94500 37.68500 25.47600  1.000 31.02000 ? 85  GLN A HA   1 
ATOM   916  H HB2  . GLN A 1 81  ? 12.55300 37.01900 24.14400  1.000 30.41000 ? 85  GLN A HB2  1 
ATOM   917  H HB3  . GLN A 1 81  ? 13.37300 38.35100 23.86500  1.000 30.41000 ? 85  GLN A HB3  1 
ATOM   918  H HG2  . GLN A 1 81  ? 15.12000 37.14600 22.98500  1.000 31.18000 ? 85  GLN A HG2  1 
ATOM   919  H HG3  . GLN A 1 81  ? 14.42200 35.77700 23.38800  1.000 31.18000 ? 85  GLN A HG3  1 
ATOM   920  H HE21 . GLN A 1 81  ? 12.41200 38.03800 22.05400  1.000 33.70000 ? 85  GLN A HE21 1 
ATOM   921  H HE22 . GLN A 1 81  ? 12.26200 37.46200 20.68800  1.000 33.70000 ? 85  GLN A HE22 1 
ATOM   922  N N    . GLN A 1 82  ? 12.25300 37.69100 27.17600  1.000 29.99570 ? 86  GLN A N    1 
ATOM   923  C CA   A GLN A 1 82  ? 11.50100 38.45600 28.16000  0.560 31.83540 ? 86  GLN A CA   1 
ATOM   924  C CA   B GLN A 1 82  ? 11.49000 38.44600 28.16200  0.440 31.62221 ? 86  GLN A CA   1 
ATOM   925  C C    . GLN A 1 82  ? 11.97400 38.22000 29.59000  1.000 31.76697 ? 86  GLN A C    1 
ATOM   926  O O    . GLN A 1 82  ? 11.63800 39.01600 30.47700  1.000 31.94594 ? 86  GLN A O    1 
ATOM   927  C CB   A GLN A 1 82  ? 10.00400 38.12500 28.05900  0.560 33.41190 ? 86  GLN A CB   1 
ATOM   928  C CB   B GLN A 1 82  ? 9.99300  38.09500 28.12500  0.440 32.78814 ? 86  GLN A CB   1 
ATOM   929  C CG   A GLN A 1 82  ? 9.38400  38.40400 26.68800  0.560 35.22264 ? 86  GLN A CG   1 
ATOM   930  C CG   B GLN A 1 82  ? 9.49000  37.26500 26.95200  0.440 34.13830 ? 86  GLN A CG   1 
ATOM   931  C CD   A GLN A 1 82  ? 9.66600  39.81100 26.18500  0.560 36.61755 ? 86  GLN A CD   1 
ATOM   932  C CD   B GLN A 1 82  ? 8.73300  36.02500 27.41500  0.440 35.19369 ? 86  GLN A CD   1 
ATOM   933  O OE1  A GLN A 1 82  ? 10.34600 39.99600 25.17400  0.560 37.22025 ? 86  GLN A OE1  1 
ATOM   934  O OE1  B GLN A 1 82  ? 9.03300  35.46400 28.47000  0.440 36.04116 ? 86  GLN A OE1  1 
ATOM   935  N NE2  A GLN A 1 82  ? 9.13800  40.80900 26.88400  0.560 37.36237 ? 86  GLN A NE2  1 
ATOM   936  N NE2  B GLN A 1 82  ? 7.74900  35.59800 26.63100  0.440 35.09368 ? 86  GLN A NE2  1 
ATOM   937  H H    A GLN A 1 82  ? 11.97300 36.88500 27.06800  0.560 36.00000 ? 86  GLN A H    1 
ATOM   938  H H    B GLN A 1 82  ? 11.97600 36.88400 27.06700  0.440 36.00000 ? 86  GLN A H    1 
ATOM   939  H HA   A GLN A 1 82  ? 11.60500 39.40100 27.96900  0.560 38.21000 ? 86  GLN A HA   1 
ATOM   940  H HA   B GLN A 1 82  ? 11.57700 39.38400 27.93200  0.440 37.96000 ? 86  GLN A HA   1 
ATOM   941  H HB2  A GLN A 1 82  ? 9.88200  37.18200 28.24900  0.560 40.10000 ? 86  GLN A HB2  1 
ATOM   942  H HB2  B GLN A 1 82  ? 9.78600  37.59400 28.93000  0.440 39.35000 ? 86  GLN A HB2  1 
ATOM   943  H HB3  A GLN A 1 82  ? 9.52500  38.66000 28.71100  0.560 40.10000 ? 86  GLN A HB3  1 
ATOM   944  H HB3  B GLN A 1 82  ? 9.49400  38.92600 28.11300  0.440 39.35000 ? 86  GLN A HB3  1 
ATOM   945  H HG2  A GLN A 1 82  ? 9.74900  37.77800 26.04400  0.560 42.27000 ? 86  GLN A HG2  1 
ATOM   946  H HG2  B GLN A 1 82  ? 8.89000  37.80400 26.41400  0.440 40.97000 ? 86  GLN A HG2  1 
ATOM   947  H HG3  A GLN A 1 82  ? 8.42200  38.29600 26.74900  0.560 42.27000 ? 86  GLN A HG3  1 
ATOM   948  H HG3  B GLN A 1 82  ? 10.24600 36.97600 26.41700  0.440 40.97000 ? 86  GLN A HG3  1 
ATOM   949  H HE21 A GLN A 1 82  ? 8.66400  40.64200 27.58200  0.560 44.84000 ? 86  GLN A HE21 1 
ATOM   950  H HE21 B GLN A 1 82  ? 7.56600  36.01700 25.90200  0.440 42.12000 ? 86  GLN A HE21 1 
ATOM   951  H HE22 A GLN A 1 82  ? 9.26900  41.62300 26.63900  0.560 44.84000 ? 86  GLN A HE22 1 
ATOM   952  H HE22 B GLN A 1 82  ? 7.29400  34.90200 26.85200  0.440 42.12000 ? 86  GLN A HE22 1 
ATOM   953  N N    . GLN A 1 83  ? 12.74500 37.15900 29.83800  1.000 30.52208 ? 87  GLN A N    1 
ATOM   954  C CA   A GLN A 1 83  ? 13.20800 36.80700 31.18100  0.610 30.28258 ? 87  GLN A CA   1 
ATOM   955  C CA   B GLN A 1 83  ? 13.20600 36.79400 31.17900  0.390 30.19046 ? 87  GLN A CA   1 
ATOM   956  C C    . GLN A 1 83  ? 14.72500 36.66300 31.11400  1.000 29.61145 ? 87  GLN A C    1 
ATOM   957  O O    . GLN A 1 83  ? 15.25400 35.59300 30.79800  1.000 27.95072 ? 87  GLN A O    1 
ATOM   958  C CB   A GLN A 1 83  ? 12.53000 35.53900 31.66800  0.610 30.72474 ? 87  GLN A CB   1 
ATOM   959  C CB   B GLN A 1 83  ? 12.51100 35.50900 31.63200  0.390 30.45628 ? 87  GLN A CB   1 
ATOM   960  C CG   A GLN A 1 83  ? 12.81200 35.23100 33.12400  0.610 30.85896 ? 87  GLN A CG   1 
ATOM   961  C CG   B GLN A 1 83  ? 10.99100 35.64300 31.62400  0.390 30.53524 ? 87  GLN A CG   1 
ATOM   962  C CD   A GLN A 1 83  ? 12.24900 33.90000 33.55000  0.610 31.41429 ? 87  GLN A CD   1 
ATOM   963  C CD   B GLN A 1 83  ? 10.25500 34.36800 31.98200  0.390 30.74053 ? 87  GLN A CD   1 
ATOM   964  O OE1  A GLN A 1 83  ? 11.24000 33.43900 33.01400  0.610 32.50916 ? 87  GLN A OE1  1 
ATOM   965  O OE1  B GLN A 1 83  ? 10.83600 33.42500 32.51700  0.390 31.17479 ? 87  GLN A OE1  1 
ATOM   966  N NE2  A GLN A 1 83  ? 12.90000 33.26600 34.51400  0.610 30.82738 ? 87  GLN A NE2  1 
ATOM   967  N NE2  B GLN A 1 83  ? 8.96000  34.33500 31.68700  0.390 30.98266 ? 87  GLN A NE2  1 
ATOM   968  H H    A GLN A 1 83  ? 13.01800 36.61600 29.23000  0.610 36.63000 ? 87  GLN A H    1 
ATOM   969  H H    B GLN A 1 83  ? 13.02100 36.62000 29.22700  0.390 36.63000 ? 87  GLN A H    1 
ATOM   970  H HA   A GLN A 1 83  ? 12.99700 37.52100 31.80200  0.610 36.35000 ? 87  GLN A HA   1 
ATOM   971  H HA   B GLN A 1 83  ? 13.00200 37.49300 31.82000  0.390 36.23000 ? 87  GLN A HA   1 
ATOM   972  H HB2  A GLN A 1 83  ? 11.57000 35.63700 31.56500  0.610 36.88000 ? 87  GLN A HB2  1 
ATOM   973  H HB2  B GLN A 1 83  ? 12.75400 34.78800 31.03000  0.390 36.56000 ? 87  GLN A HB2  1 
ATOM   974  H HB3  A GLN A 1 83  ? 12.84500 34.79100 31.13800  0.610 36.88000 ? 87  GLN A HB3  1 
ATOM   975  H HB3  B GLN A 1 83  ? 12.79200 35.29700 32.53500  0.390 36.56000 ? 87  GLN A HB3  1 
ATOM   976  H HG2  A GLN A 1 83  ? 13.77200 35.21100 33.26300  0.610 37.04000 ? 87  GLN A HG2  1 
ATOM   977  H HG2  B GLN A 1 83  ? 10.73600 36.32100 32.27000  0.390 36.65000 ? 87  GLN A HG2  1 
ATOM   978  H HG3  A GLN A 1 83  ? 12.41100 35.91900 33.67700  0.610 37.04000 ? 87  GLN A HG3  1 
ATOM   979  H HG3  B GLN A 1 83  ? 10.70600 35.90700 30.73500  0.390 36.65000 ? 87  GLN A HG3  1 
ATOM   980  H HE21 A GLN A 1 83  ? 13.60300 33.61800 34.86200  0.610 37.00000 ? 87  GLN A HE21 1 
ATOM   981  H HE21 B GLN A 1 83  ? 8.58700  35.01400 31.31400  0.390 37.19000 ? 87  GLN A HE21 1 
ATOM   982  H HE22 A GLN A 1 83  ? 12.61900 32.50300 34.79400  0.610 37.00000 ? 87  GLN A HE22 1 
ATOM   983  H HE22 B GLN A 1 83  ? 8.49500  33.63500 31.86900  0.390 37.19000 ? 87  GLN A HE22 1 
ATOM   984  N N    . ALA A 1 84  ? 15.42100 37.76100 31.42400  1.000 30.32469 ? 88  ALA A N    1 
ATOM   985  C CA   . ALA A 1 84  ? 16.87100 37.82900 31.26700  1.000 30.20099 ? 88  ALA A CA   1 
ATOM   986  C C    . ALA A 1 84  ? 17.62600 36.86700 32.17500  1.000 30.62736 ? 88  ALA A C    1 
ATOM   987  O O    . ALA A 1 84  ? 18.78100 36.53400 31.88000  1.000 31.56168 ? 88  ALA A O    1 
ATOM   988  C CB   . ALA A 1 84  ? 17.34000 39.25900 31.53200  1.000 30.57209 ? 88  ALA A CB   1 
ATOM   989  H H    . ALA A 1 84  ? 15.07300 38.48600 31.72900  1.000 36.40000 ? 88  ALA A H    1 
ATOM   990  H HA   . ALA A 1 84  ? 17.08800 37.58500 30.35400  1.000 36.25000 ? 88  ALA A HA   1 
ATOM   991  H HB1  . ALA A 1 84  ? 18.30400 39.29800 31.43600  1.000 36.69000 ? 88  ALA A HB1  1 
ATOM   992  H HB2  . ALA A 1 84  ? 16.92000 39.85300 30.89100  1.000 36.69000 ? 88  ALA A HB2  1 
ATOM   993  H HB3  . ALA A 1 84  ? 17.08600 39.51300 32.43300  1.000 36.69000 ? 88  ALA A HB3  1 
ATOM   994  N N    . ASP A 1 85  ? 17.01900 36.41400 33.26800  1.000 29.66408 ? 89  ASP A N    1 
ATOM   995  C CA   . ASP A 1 85  ? 17.68200 35.49500 34.18600  1.000 29.57723 ? 89  ASP A CA   1 
ATOM   996  C C    . ASP A 1 85  ? 17.30300 34.03700 33.93800  1.000 27.74017 ? 89  ASP A C    1 
ATOM   997  O O    . ASP A 1 85  ? 17.69000 33.16500 34.72100  1.000 28.89031 ? 89  ASP A O    1 
ATOM   998  C CB   . ASP A 1 85  ? 17.38100 35.88600 35.63600  1.000 32.48284 ? 89  ASP A CB   1 
ATOM   999  C CG   . ASP A 1 85  ? 15.92300 35.70600 35.99800  1.000 34.97788 ? 89  ASP A CG   1 
ATOM   1000 O OD1  . ASP A 1 85  ? 15.10300 35.49400 35.08500  1.000 35.94642 ? 89  ASP A OD1  1 
ATOM   1001 O OD2  . ASP A 1 85  ? 15.58900 35.77000 37.20200  1.000 36.78336 ? 89  ASP A OD2  1 
ATOM   1002 H H    . ASP A 1 85  ? 16.21900 36.62700 33.50000  1.000 35.61000 ? 89  ASP A H    1 
ATOM   1003 H HA   . ASP A 1 85  ? 18.64000 35.57000 34.05600  1.000 35.50000 ? 89  ASP A HA   1 
ATOM   1004 H HB2  . ASP A 1 85  ? 17.90900 35.32900 36.22900  1.000 38.98000 ? 89  ASP A HB2  1 
ATOM   1005 H HB3  . ASP A 1 85  ? 17.61000 36.82000 35.76600  1.000 38.98000 ? 89  ASP A HB3  1 
ATOM   1006 N N    . LEU A 1 86  ? 16.58100 33.74700 32.85200  1.000 24.97931 ? 90  LEU A N    1 
ATOM   1007 C CA   . LEU A 1 86  ? 16.08500 32.39000 32.65000  1.000 22.91327 ? 90  LEU A CA   1 
ATOM   1008 C C    . LEU A 1 86  ? 17.22100 31.41400 32.36500  1.000 21.18938 ? 90  LEU A C    1 
ATOM   1009 O O    . LEU A 1 86  ? 17.32500 30.36200 33.00900  1.000 20.85776 ? 90  LEU A O    1 
ATOM   1010 C CB   . LEU A 1 86  ? 15.05500 32.36100 31.52000  1.000 22.71851 ? 90  LEU A CB   1 
ATOM   1011 C CG   . LEU A 1 86  ? 14.51700 30.96500 31.19300  1.000 21.81841 ? 90  LEU A CG   1 
ATOM   1012 C CD1  . LEU A 1 86  ? 13.84100 30.32500 32.39400  1.000 22.26846 ? 90  LEU A CD1  1 
ATOM   1013 C CD2  . LEU A 1 86  ? 13.54800 31.05300 30.02200  1.000 21.71050 ? 90  LEU A CD2  1 
ATOM   1014 H H    . LEU A 1 86  ? 16.37100 34.30600 32.23300  1.000 29.98000 ? 90  LEU A H    1 
ATOM   1015 H HA   . LEU A 1 86  ? 15.64400 32.10600 33.46600  1.000 27.50000 ? 90  LEU A HA   1 
ATOM   1016 H HB2  . LEU A 1 86  ? 14.30000 32.91400 31.77500  1.000 27.27000 ? 90  LEU A HB2  1 
ATOM   1017 H HB3  . LEU A 1 86  ? 15.46800 32.71300 30.71600  1.000 27.27000 ? 90  LEU A HB3  1 
ATOM   1018 H HG   . LEU A 1 86  ? 15.26300 30.39400 30.95000  1.000 26.19000 ? 90  LEU A HG   1 
ATOM   1019 H HD11 . LEU A 1 86  ? 13.38400 29.51900 32.10600  1.000 26.73000 ? 90  LEU A HD11 1 
ATOM   1020 H HD12 . LEU A 1 86  ? 14.51500 30.10500 33.05500  1.000 26.73000 ? 90  LEU A HD12 1 
ATOM   1021 H HD13 . LEU A 1 86  ? 13.20200 30.95100 32.76800  1.000 26.73000 ? 90  LEU A HD13 1 
ATOM   1022 H HD21 . LEU A 1 86  ? 13.22500 30.16300 29.81200  1.000 26.06000 ? 90  LEU A HD21 1 
ATOM   1023 H HD22 . LEU A 1 86  ? 12.80400 31.62400 30.27000  1.000 26.06000 ? 90  LEU A HD22 1 
ATOM   1024 H HD23 . LEU A 1 86  ? 14.01100 31.42700 29.25600  1.000 26.06000 ? 90  LEU A HD23 1 
ATOM   1025 N N    . LEU A 1 87  ? 18.07400 31.73000 31.38600  1.000 21.79209 ? 91  LEU A N    1 
ATOM   1026 C CA   . LEU A 1 87  ? 19.04700 30.74200 30.92600  1.000 20.92619 ? 91  LEU A CA   1 
ATOM   1027 C C    . LEU A 1 87  ? 20.02800 30.34300 32.01900  1.000 20.70511 ? 91  LEU A C    1 
ATOM   1028 O O    . LEU A 1 87  ? 20.48200 29.19500 32.04200  1.000 19.27073 ? 91  LEU A O    1 
ATOM   1029 C CB   . LEU A 1 87  ? 19.81400 31.25100 29.70800  1.000 20.81565 ? 91  LEU A CB   1 
ATOM   1030 C CG   . LEU A 1 87  ? 19.00800 31.38400 28.41200  1.000 21.16833 ? 91  LEU A CG   1 
ATOM   1031 C CD1  . LEU A 1 87  ? 19.92300 31.83100 27.26400  1.000 23.39228 ? 91  LEU A CD1  1 
ATOM   1032 C CD2  . LEU A 1 87  ? 18.29300 30.11600 28.05600  1.000 21.07884 ? 91  LEU A CD2  1 
ATOM   1033 H H    . LEU A 1 87  ? 18.10700 32.48900 30.98300  1.000 26.16000 ? 91  LEU A H    1 
ATOM   1034 H HA   . LEU A 1 87  ? 18.55200 29.95200 30.65900  1.000 25.12000 ? 91  LEU A HA   1 
ATOM   1035 H HB2  . LEU A 1 87  ? 20.16600 32.13000 29.91800  1.000 24.98000 ? 91  LEU A HB2  1 
ATOM   1036 H HB3  . LEU A 1 87  ? 20.54300 30.63600 29.53100  1.000 24.98000 ? 91  LEU A HB3  1 
ATOM   1037 H HG   . LEU A 1 87  ? 18.32400 32.05800 28.54900  1.000 25.41000 ? 91  LEU A HG   1 
ATOM   1038 H HD11 . LEU A 1 87  ? 19.39000 31.94800 26.46200  1.000 28.08000 ? 91  LEU A HD11 1 
ATOM   1039 H HD12 . LEU A 1 87  ? 20.34500 32.67100 27.50500  1.000 28.08000 ? 91  LEU A HD12 1 
ATOM   1040 H HD13 . LEU A 1 87  ? 20.59900 31.15200 27.11600  1.000 28.08000 ? 91  LEU A HD13 1 
ATOM   1041 H HD21 . LEU A 1 87  ? 17.94800 30.19000 27.15300  1.000 25.30000 ? 91  LEU A HD21 1 
ATOM   1042 H HD22 . LEU A 1 87  ? 18.91700 29.37500 28.11100  1.000 25.30000 ? 91  LEU A HD22 1 
ATOM   1043 H HD23 . LEU A 1 87  ? 17.56300 29.98000 28.68000  1.000 25.30000 ? 91  LEU A HD23 1 
ATOM   1044 N N    . ASP A 1 88  ? 20.38100 31.26700 32.91000  1.000 21.84209 ? 92  ASP A N    1 
ATOM   1045 C CA   . ASP A 1 88  ? 21.31000 30.97200 33.99200  1.000 22.62113 ? 92  ASP A CA   1 
ATOM   1046 C C    . ASP A 1 88  ? 20.63200 30.36100 35.21000  1.000 21.03936 ? 92  ASP A C    1 
ATOM   1047 O O    . ASP A 1 88  ? 21.31300 30.09200 36.19800  1.000 21.34203 ? 92  ASP A O    1 
ATOM   1048 C CB   . ASP A 1 88  ? 22.00000 32.25500 34.46300  1.000 25.41884 ? 92  ASP A CB   1 
ATOM   1049 C CG   . ASP A 1 88  ? 23.06800 32.75700 33.51100  1.000 28.89557 ? 92  ASP A CG   1 
ATOM   1050 O OD1  . ASP A 1 88  ? 23.62200 31.96300 32.73300  1.000 28.62975 ? 92  ASP A OD1  1 
ATOM   1051 O OD2  . ASP A 1 88  ? 23.37500 33.96900 33.57200  1.000 32.13017 ? 92  ASP A OD2  1 
ATOM   1052 H H    . ASP A 1 88  ? 20.09300 32.07800 32.90800  1.000 26.22000 ? 92  ASP A H    1 
ATOM   1053 H HA   . ASP A 1 88  ? 21.97100 30.35400 33.64400  1.000 27.15000 ? 92  ASP A HA   1 
ATOM   1054 H HB2  . ASP A 1 88  ? 21.33400 32.95400 34.55500  1.000 30.51000 ? 92  ASP A HB2  1 
ATOM   1055 H HB3  . ASP A 1 88  ? 22.42400 32.08600 35.31900  1.000 30.51000 ? 92  ASP A HB3  1 
ATOM   1056 N N    . THR A 1 89  ? 19.31800 30.17000 35.18300  1.000 19.74447 ? 93  THR A N    1 
ATOM   1057 C CA   . THR A 1 89  ? 18.61100 29.69300 36.36200  1.000 19.61025 ? 93  THR A CA   1 
ATOM   1058 C C    . THR A 1 89  ? 18.99600 28.25000 36.66800  1.000 18.60749 ? 93  THR A C    1 
ATOM   1059 O O    . THR A 1 89  ? 18.87800 27.38900 35.77900  1.000 18.51538 ? 93  THR A O    1 
ATOM   1060 C CB   . THR A 1 89  ? 17.10200 29.78000 36.16100  1.000 20.90251 ? 93  THR A CB   1 
ATOM   1061 O OG1  . THR A 1 89  ? 16.70800 31.15200 36.10100  1.000 23.26332 ? 93  THR A OG1  1 
ATOM   1062 C CG2  . THR A 1 89  ? 16.34800 29.09600 37.31300  1.000 21.55522 ? 93  THR A CG2  1 
ATOM   1063 H H    . THR A 1 89  ? 18.81700 30.30800 34.49900  1.000 23.70000 ? 93  THR A H    1 
ATOM   1064 H HA   . THR A 1 89  ? 18.85800 30.25300 37.11400  1.000 23.54000 ? 93  THR A HA   1 
ATOM   1065 H HB   . THR A 1 89  ? 16.86700 29.33000 35.33400  1.000 25.09000 ? 93  THR A HB   1 
ATOM   1066 H HG1  . THR A 1 89  ? 17.10800 31.53900 35.47200  1.000 27.92000 ? 93  THR A HG1  1 
ATOM   1067 H HG21 . THR A 1 89  ? 15.41100 29.34300 37.29000  1.000 25.87000 ? 93  THR A HG21 1 
ATOM   1068 H HG22 . THR A 1 89  ? 16.42200 28.13300 37.23200  1.000 25.87000 ? 93  THR A HG22 1 
ATOM   1069 H HG23 . THR A 1 89  ? 16.72500 29.37000 38.16400  1.000 25.87000 ? 93  THR A HG23 1 
ATOM   1070 N N    A PRO A 1 90  ? 19.47900 27.95100 37.86500  0.520 18.58907 ? 94  PRO A N    1 
ATOM   1071 N N    B PRO A 1 90  ? 19.37800 27.92400 37.91000  0.480 18.83647 ? 94  PRO A N    1 
ATOM   1072 C CA   A PRO A 1 90  ? 19.73500 26.55000 38.21700  0.520 18.56538 ? 94  PRO A CA   1 
ATOM   1073 C CA   B PRO A 1 90  ? 19.77800 26.54800 38.22400  0.480 18.66803 ? 94  PRO A CA   1 
ATOM   1074 C C    A PRO A 1 90  ? 18.43500 25.77800 38.36900  0.520 18.32325 ? 94  PRO A C    1 
ATOM   1075 C C    B PRO A 1 90  ? 18.57800 25.67400 38.58600  0.480 18.14428 ? 94  PRO A C    1 
ATOM   1076 O O    A PRO A 1 90  ? 17.43300 26.28700 38.88700  0.520 18.68382 ? 94  PRO A O    1 
ATOM   1077 O O    B PRO A 1 90  ? 17.79900 26.01800 39.48300  0.480 17.88109 ? 94  PRO A O    1 
ATOM   1078 C CB   A PRO A 1 90  ? 20.49400 26.63500 39.54800  0.520 18.51801 ? 94  PRO A CB   1 
ATOM   1079 C CB   B PRO A 1 90  ? 20.73500 26.71900 39.40900  0.480 18.76804 ? 94  PRO A CB   1 
ATOM   1080 C CG   A PRO A 1 90  ? 21.02200 28.02800 39.59500  0.520 17.79950 ? 94  PRO A CG   1 
ATOM   1081 C CG   B PRO A 1 90  ? 20.24700 27.98100 40.09600  0.480 18.79436 ? 94  PRO A CG   1 
ATOM   1082 C CD   A PRO A 1 90  ? 20.04000 28.88300 38.86000  0.520 18.01795 ? 94  PRO A CD   1 
ATOM   1083 C CD   B PRO A 1 90  ? 19.60200 28.85300 39.02800  0.480 18.78646 ? 94  PRO A CD   1 
ATOM   1084 H HA   A PRO A 1 90  ? 20.29900 26.12600 37.55100  0.520 22.29000 ? 94  PRO A HA   1 
ATOM   1085 H HA   B PRO A 1 90  ? 20.24400 26.14900 37.47300  0.480 22.41000 ? 94  PRO A HA   1 
ATOM   1086 H HB2  A PRO A 1 90  ? 19.88700 26.46700 40.28600  0.520 22.23000 ? 94  PRO A HB2  1 
ATOM   1087 H HB2  B PRO A 1 90  ? 20.67600 25.95300 40.00100  0.480 22.53000 ? 94  PRO A HB2  1 
ATOM   1088 H HB3  A PRO A 1 90  ? 21.21700 25.98800 39.55900  0.520 22.23000 ? 94  PRO A HB3  1 
ATOM   1089 H HB3  B PRO A 1 90  ? 21.64600 26.82300 39.09100  0.480 22.53000 ? 94  PRO A HB3  1 
ATOM   1090 H HG2  A PRO A 1 90  ? 21.09800 28.31500 40.51900  0.520 21.37000 ? 94  PRO A HG2  1 
ATOM   1091 H HG2  B PRO A 1 90  ? 19.59900 27.74600 40.77900  0.480 22.56000 ? 94  PRO A HG2  1 
ATOM   1092 H HG3  A PRO A 1 90  ? 21.89000 28.06000 39.16500  0.520 21.37000 ? 94  PRO A HG3  1 
ATOM   1093 H HG3  B PRO A 1 90  ? 21.00100 28.44100 40.49800  0.480 22.56000 ? 94  PRO A HG3  1 
ATOM   1094 H HD2  A PRO A 1 90  ? 19.34900 29.21000 39.45700  0.520 21.63000 ? 94  PRO A HD2  1 
ATOM   1095 H HD2  B PRO A 1 90  ? 18.76100 29.21900 39.34400  0.480 22.55000 ? 94  PRO A HD2  1 
ATOM   1096 H HD3  A PRO A 1 90  ? 20.48500 29.62800 38.42600  0.520 21.63000 ? 94  PRO A HD3  1 
ATOM   1097 H HD3  B PRO A 1 90  ? 20.19800 29.57100 38.76400  0.480 22.55000 ? 94  PRO A HD3  1 
ATOM   1098 N N    . ILE A 1 91  ? 18.46700 24.52800 37.90600  1.000 18.35220 ? 95  ILE A N    1 
ATOM   1099 C CA   . ILE A 1 91  ? 17.35600 23.59300 38.07700  1.000 19.17335 ? 95  ILE A CA   1 
ATOM   1100 C C    . ILE A 1 91  ? 17.89400 22.34600 38.77400  1.000 18.86542 ? 95  ILE A C    1 
ATOM   1101 O O    . ILE A 1 91  ? 18.81900 21.68900 38.27900  1.000 17.93373 ? 95  ILE A O    1 
ATOM   1102 C CB   . ILE A 1 91  ? 16.72800 23.19700 36.72900  1.000 21.27097 ? 95  ILE A CB   1 
ATOM   1103 C CG1  . ILE A 1 91  ? 16.23300 24.42400 35.95900  1.000 23.47913 ? 95  ILE A CG1  1 
ATOM   1104 C CG2  . ILE A 1 91  ? 15.63600 22.16900 36.93600  1.000 22.10528 ? 95  ILE A CG2  1 
ATOM   1105 C CD1  . ILE A 1 91  ? 15.19100 25.22800 36.66000  1.000 25.78204 ? 95  ILE A CD1  1 
ATOM   1106 H H    A ILE A 1 91  ? 19.13600 24.19200 37.48100  0.520 22.03000 ? 95  ILE A H    1 
ATOM   1107 H H    B ILE A 1 91  ? 19.04300 24.26400 37.32400  0.480 22.03000 ? 95  ILE A H    1 
ATOM   1108 H HA   . ILE A 1 91  ? 16.68200 24.01100 38.63600  1.000 23.01000 ? 95  ILE A HA   1 
ATOM   1109 H HB   . ILE A 1 91  ? 17.41800 22.79000 36.18100  1.000 25.53000 ? 95  ILE A HB   1 
ATOM   1110 H HG12 . ILE A 1 91  ? 16.98800 25.00900 35.79200  1.000 28.18000 ? 95  ILE A HG12 1 
ATOM   1111 H HG13 . ILE A 1 91  ? 15.85200 24.12600 35.11800  1.000 28.18000 ? 95  ILE A HG13 1 
ATOM   1112 H HG21 . ILE A 1 91  ? 15.08600 22.12700 36.13800  1.000 26.53000 ? 95  ILE A HG21 1 
ATOM   1113 H HG22 . ILE A 1 91  ? 16.04400 21.30400 37.10200  1.000 26.53000 ? 95  ILE A HG22 1 
ATOM   1114 H HG23 . ILE A 1 91  ? 15.09600 22.43100 37.69700  1.000 26.53000 ? 95  ILE A HG23 1 
ATOM   1115 H HD11 . ILE A 1 91  ? 14.88800 25.93600 36.07000  1.000 30.94000 ? 95  ILE A HD11 1 
ATOM   1116 H HD12 . ILE A 1 91  ? 14.44800 24.64900 36.89200  1.000 30.94000 ? 95  ILE A HD12 1 
ATOM   1117 H HD13 . ILE A 1 91  ? 15.57600 25.61000 37.46400  1.000 30.94000 ? 95  ILE A HD13 1 
ATOM   1118 N N    . ARG A 1 92  ? 17.31200 22.00400 39.91300  1.000 19.51813 ? 96  ARG A N    1 
ATOM   1119 C CA   . ARG A 1 92  ? 17.63600 20.77500 40.61200  1.000 19.55498 ? 96  ARG A CA   1 
ATOM   1120 C C    . ARG A 1 92  ? 16.54700 19.74000 40.37900  1.000 19.26020 ? 96  ARG A C    1 
ATOM   1121 O O    . ARG A 1 92  ? 15.37400 20.07700 40.15800  1.000 21.30255 ? 96  ARG A O    1 
ATOM   1122 C CB   . ARG A 1 92  ? 17.79500 21.04800 42.10700  1.000 20.76038 ? 96  ARG A CB   1 
ATOM   1123 C CG   . ARG A 1 92  ? 18.75800 22.19400 42.38000  1.000 22.02633 ? 96  ARG A CG   1 
ATOM   1124 C CD   . ARG A 1 92  ? 18.86700 22.47500 43.85700  1.000 24.40556 ? 96  ARG A CD   1 
ATOM   1125 N NE   . ARG A 1 92  ? 19.11500 21.23100 44.55500  1.000 24.28712 ? 96  ARG A NE   1 
ATOM   1126 C CZ   . ARG A 1 92  ? 18.59800 20.91100 45.73000  1.000 23.97919 ? 96  ARG A CZ   1 
ATOM   1127 N NH1  . ARG A 1 92  ? 17.83600 21.75600 46.40300  1.000 24.75560 ? 96  ARG A NH1  1 
ATOM   1128 N NH2  . ARG A 1 92  ? 18.83500 19.70300 46.22600  1.000 24.92930 ? 96  ARG A NH2  1 
ATOM   1129 H H    . ARG A 1 92  ? 16.71300 22.47900 40.30800  1.000 23.43000 ? 96  ARG A H    1 
ATOM   1130 H HA   . ARG A 1 92  ? 18.47000 20.40900 40.27800  1.000 23.48000 ? 96  ARG A HA   1 
ATOM   1131 H HB2  . ARG A 1 92  ? 16.93100 21.28200 42.48200  1.000 24.92000 ? 96  ARG A HB2  1 
ATOM   1132 H HB3  . ARG A 1 92  ? 18.14000 20.25300 42.54200  1.000 24.92000 ? 96  ARG A HB3  1 
ATOM   1133 H HG2  . ARG A 1 92  ? 19.63900 21.96100 42.04700  1.000 26.44000 ? 96  ARG A HG2  1 
ATOM   1134 H HG3  . ARG A 1 92  ? 18.43800 22.99600 41.93800  1.000 26.44000 ? 96  ARG A HG3  1 
ATOM   1135 H HD2  . ARG A 1 92  ? 19.60400 23.08400 44.02400  1.000 29.30000 ? 96  ARG A HD2  1 
ATOM   1136 H HD3  . ARG A 1 92  ? 18.03800 22.86000 44.18200  1.000 29.30000 ? 96  ARG A HD3  1 
ATOM   1137 H HE   . ARG A 1 92  ? 19.63600 20.65900 44.18000  1.000 29.15000 ? 96  ARG A HE   1 
ATOM   1138 H HH11 . ARG A 1 92  ? 17.66800 22.53500 46.07900  1.000 29.72000 ? 96  ARG A HH11 1 
ATOM   1139 H HH12 . ARG A 1 92  ? 17.51000 21.52800 47.16500  1.000 29.72000 ? 96  ARG A HH12 1 
ATOM   1140 H HH21 . ARG A 1 92  ? 19.31900 19.14500 45.78600  1.000 29.92000 ? 96  ARG A HH21 1 
ATOM   1141 H HH22 . ARG A 1 92  ? 18.50600 19.47900 46.98900  1.000 29.92000 ? 96  ARG A HH22 1 
ATOM   1142 N N    . TYR A 1 93  ? 16.94600 18.47300 40.41300  1.000 17.45736 ? 97  TYR A N    1 
ATOM   1143 C CA   . TYR A 1 93  ? 16.02900 17.38700 40.11100  1.000 17.85214 ? 97  TYR A CA   1 
ATOM   1144 C C    . TYR A 1 93  ? 16.44200 16.13700 40.86800  1.000 19.29705 ? 97  TYR A C    1 
ATOM   1145 O O    . TYR A 1 93  ? 17.60700 15.95800 41.23700  1.000 19.18914 ? 97  TYR A O    1 
ATOM   1146 C CB   . TYR A 1 93  ? 15.95100 17.12700 38.59500  1.000 16.90466 ? 97  TYR A CB   1 
ATOM   1147 C CG   . TYR A 1 93  ? 17.30500 17.04600 37.91600  1.000 15.20182 ? 97  TYR A CG   1 
ATOM   1148 C CD1  . TYR A 1 93  ? 17.92900 18.18700 37.45400  1.000 15.53607 ? 97  TYR A CD1  1 
ATOM   1149 C CD2  . TYR A 1 93  ? 17.94700 15.82700 37.74200  1.000 15.18866 ? 97  TYR A CD2  1 
ATOM   1150 C CE1  . TYR A 1 93  ? 19.17100 18.12000 36.82600  1.000 14.95179 ? 97  TYR A CE1  1 
ATOM   1151 C CE2  . TYR A 1 93  ? 19.21400 15.75400 37.13200  1.000 14.66228 ? 97  TYR A CE2  1 
ATOM   1152 C CZ   . TYR A 1 93  ? 19.82200 16.91300 36.68700  1.000 14.84125 ? 97  TYR A CZ   1 
ATOM   1153 O OH   . TYR A 1 93  ? 21.04200 16.89400 36.05200  1.000 15.90191 ? 97  TYR A OH   1 
ATOM   1154 H H    . TYR A 1 93  ? 17.74400 18.21900 40.60800  1.000 20.96000 ? 97  TYR A H    1 
ATOM   1155 H HA   . TYR A 1 93  ? 15.14000 17.61900 40.42100  1.000 21.43000 ? 97  TYR A HA   1 
ATOM   1156 H HB2  . TYR A 1 93  ? 15.49500 16.28300 38.44700  1.000 20.29000 ? 97  TYR A HB2  1 
ATOM   1157 H HB3  . TYR A 1 93  ? 15.45400 17.84900 38.18000  1.000 20.29000 ? 97  TYR A HB3  1 
ATOM   1158 H HD1  . TYR A 1 93  ? 17.51400 19.01300 37.56300  1.000 18.65000 ? 97  TYR A HD1  1 
ATOM   1159 H HD2  . TYR A 1 93  ? 17.53400 15.04600 38.03300  1.000 18.23000 ? 97  TYR A HD2  1 
ATOM   1160 H HE1  . TYR A 1 93  ? 19.56400 18.89600 36.49700  1.000 17.95000 ? 97  TYR A HE1  1 
ATOM   1161 H HE2  . TYR A 1 93  ? 19.63800 14.93300 37.02800  1.000 17.60000 ? 97  TYR A HE2  1 
ATOM   1162 H HH   . TYR A 1 93  ? 21.34000 16.10900 36.02500  1.000 19.09000 ? 97  TYR A HH   1 
ATOM   1163 N N    . GLY A 1 94  ? 15.45500 15.28000 41.11200  1.000 20.31033 ? 98  GLY A N    1 
ATOM   1164 C CA   . GLY A 1 94  ? 15.68600 14.04900 41.82700  1.000 21.15780 ? 98  GLY A CA   1 
ATOM   1165 C C    . GLY A 1 94  ? 15.98200 12.88800 40.90600  1.000 21.38677 ? 98  GLY A C    1 
ATOM   1166 O O    . GLY A 1 94  ? 15.87900 12.98300 39.68700  1.000 20.73933 ? 98  GLY A O    1 
ATOM   1167 H H    . GLY A 1 94  ? 14.63800 15.39700 40.86900  1.000 24.38000 ? 98  GLY A H    1 
ATOM   1168 H HA2  . GLY A 1 94  ? 16.44200 14.16400 42.42500  1.000 25.40000 ? 98  GLY A HA2  1 
ATOM   1169 H HA3  . GLY A 1 94  ? 14.90000 13.83100 42.35100  1.000 25.40000 ? 98  GLY A HA3  1 
ATOM   1170 N N    . LYS A 1 95  ? 16.35900 11.77400 41.53100  1.000 22.25793 ? 99  LYS A N    1 
ATOM   1171 C CA   . LYS A 1 95  ? 16.66100 10.56200 40.78500  1.000 25.55833 ? 99  LYS A CA   1 
ATOM   1172 C C    . LYS A 1 95  ? 15.48700 10.12400 39.92200  1.000 26.05576 ? 99  LYS A C    1 
ATOM   1173 O O    . LYS A 1 95  ? 15.69900 9.59800  38.82400  1.000 27.09009 ? 99  LYS A O    1 
ATOM   1174 C CB   . LYS A 1 95  ? 17.07500 9.44200  41.74200  1.000 29.48775 ? 99  LYS A CB   1 
ATOM   1175 C CG   . LYS A 1 95  ? 17.83300 8.33300  41.04000  1.000 34.10409 ? 99  LYS A CG   1 
ATOM   1176 C CD   . LYS A 1 95  ? 18.51100 7.35300  41.98700  1.000 37.79664 ? 99  LYS A CD   1 
ATOM   1177 C CE   . LYS A 1 95  ? 19.45500 6.44500  41.20300  1.000 40.67330 ? 99  LYS A CE   1 
ATOM   1178 N NZ   . LYS A 1 95  ? 19.59900 5.07800  41.79100  1.000 42.28928 ? 99  LYS A NZ   1 
ATOM   1179 H H    . LYS A 1 95  ? 16.44600 11.69600 42.38200  1.000 26.72000 ? 99  LYS A H    1 
ATOM   1180 H HA   . LYS A 1 95  ? 17.41000 10.74000 40.19600  1.000 30.68000 ? 99  LYS A HA   1 
ATOM   1181 H HB2  . LYS A 1 95  ? 17.65000 9.81000  42.43100  1.000 35.39000 ? 99  LYS A HB2  1 
ATOM   1182 H HB3  . LYS A 1 95  ? 16.28000 9.05700  42.14300  1.000 35.39000 ? 99  LYS A HB3  1 
ATOM   1183 H HG2  . LYS A 1 95  ? 17.21200 7.83000  40.49000  1.000 40.93000 ? 99  LYS A HG2  1 
ATOM   1184 H HG3  . LYS A 1 95  ? 18.52200 8.72900  40.48400  1.000 40.93000 ? 99  LYS A HG3  1 
ATOM   1185 H HD2  . LYS A 1 95  ? 19.02500 7.84100  42.64900  1.000 45.37000 ? 99  LYS A HD2  1 
ATOM   1186 H HD3  . LYS A 1 95  ? 17.84100 6.80500  42.42500  1.000 45.37000 ? 99  LYS A HD3  1 
ATOM   1187 H HE2  . LYS A 1 95  ? 19.11300 6.34400  40.30000  1.000 48.81000 ? 99  LYS A HE2  1 
ATOM   1188 H HE3  . LYS A 1 95  ? 20.33500 6.85200  41.18100  1.000 48.81000 ? 99  LYS A HE3  1 
ATOM   1189 H HZ1  . LYS A 1 95  ? 20.16400 4.59400  41.30200  1.000 50.75000 ? 99  LYS A HZ1  1 
ATOM   1190 H HZ2  . LYS A 1 95  ? 19.91300 5.13500  42.62200  1.000 50.75000 ? 99  LYS A HZ2  1 
ATOM   1191 H HZ3  . LYS A 1 95  ? 18.80900 4.66900  41.80900  1.000 50.75000 ? 99  LYS A HZ3  1 
ATOM   1192 N N    . ASN A 1 96  ? 14.25000 10.35100 40.38600  1.000 25.66624 ? 100 ASN A N    1 
ATOM   1193 C CA   . ASN A 1 96  ? 13.06900 9.93000  39.64200  1.000 28.34550 ? 100 ASN A CA   1 
ATOM   1194 C C    . ASN A 1 96  ? 12.87700 10.73900 38.36600  1.000 27.81386 ? 100 ASN A C    1 
ATOM   1195 O O    . ASN A 1 96  ? 12.11300 10.31500 37.49200  1.000 28.98505 ? 100 ASN A O    1 
ATOM   1196 C CB   . ASN A 1 96  ? 11.82300 9.97900  40.54100  1.000 30.95898 ? 100 ASN A CB   1 
ATOM   1197 C CG   . ASN A 1 96  ? 11.49300 11.37800 41.03100  1.000 33.79879 ? 100 ASN A CG   1 
ATOM   1198 O OD1  . ASN A 1 96  ? 12.28500 12.30700 40.89800  1.000 34.85681 ? 100 ASN A OD1  1 
ATOM   1199 N ND2  . ASN A 1 96  ? 10.31300 11.52600 41.62900  1.000 36.39121 ? 100 ASN A ND2  1 
ATOM   1200 H H    . ASN A 1 96  ? 14.07300 10.74600 41.12900  1.000 30.81000 ? 100 ASN A H    1 
ATOM   1201 H HA   . ASN A 1 96  ? 13.17500 9.00400  39.37300  1.000 34.02000 ? 100 ASN A HA   1 
ATOM   1202 H HB2  . ASN A 1 96  ? 11.06000 9.65100  40.04000  1.000 37.16000 ? 100 ASN A HB2  1 
ATOM   1203 H HB3  . ASN A 1 96  ? 11.97400 9.41900  41.31900  1.000 37.16000 ? 100 ASN A HB3  1 
ATOM   1204 H HD21 . ASN A 1 96  ? 10.07400 12.29700 41.92600  1.000 43.68000 ? 100 ASN A HD21 1 
ATOM   1205 H HD22 . ASN A 1 96  ? 9.78800  10.85000 41.71900  1.000 43.68000 ? 100 ASN A HD22 1 
ATOM   1206 N N    . ALA A 1 97  ? 13.56500 11.87500 38.22400  1.000 25.47937 ? 101 ALA A N    1 
ATOM   1207 C CA   . ALA A 1 97  ? 13.52100 12.61700 36.96700  1.000 25.46095 ? 101 ALA A CA   1 
ATOM   1208 C C    . ALA A 1 97  ? 14.35600 11.96900 35.87200  1.000 24.08973 ? 101 ALA A C    1 
ATOM   1209 O O    . ALA A 1 97  ? 14.16500 12.28800 34.69300  1.000 23.93971 ? 101 ALA A O    1 
ATOM   1210 C CB   . ALA A 1 97  ? 14.00900 14.05000 37.16600  1.000 25.48200 ? 101 ALA A CB   1 
ATOM   1211 H H    . ALA A 1 97  ? 14.05700 12.23100 38.83300  1.000 30.58000 ? 101 ALA A H    1 
ATOM   1212 H HA   . ALA A 1 97  ? 12.59600 12.65000 36.67500  1.000 30.56000 ? 101 ALA A HA   1 
ATOM   1213 H HB1  . ALA A 1 97  ? 13.94200 14.52700 36.32500  1.000 30.59000 ? 101 ALA A HB1  1 
ATOM   1214 H HB2  . ALA A 1 97  ? 13.45600 14.48200 37.83600  1.000 30.59000 ? 101 ALA A HB2  1 
ATOM   1215 H HB3  . ALA A 1 97  ? 14.93300 14.03000 37.46200  1.000 30.59000 ? 101 ALA A HB3  1 
ATOM   1216 N N    . LEU A 1 98  ? 15.26500 11.06700 36.22600  1.000 24.92141 ? 102 LEU A N    1 
ATOM   1217 C CA   . LEU A 1 98  ? 16.20400 10.47900 35.27000  1.000 25.58991 ? 102 LEU A CA   1 
ATOM   1218 C C    . LEU A 1 98  ? 15.56400 9.28100  34.59100  1.000 27.82702 ? 102 LEU A C    1 
ATOM   1219 O O    . LEU A 1 98  ? 15.50800 8.18800  35.15600  1.000 30.13519 ? 102 LEU A O    1 
ATOM   1220 C CB   . LEU A 1 98  ? 17.47800 10.02600 35.96700  1.000 25.17407 ? 102 LEU A CB   1 
ATOM   1221 C CG   . LEU A 1 98  ? 18.39000 11.10500 36.51400  1.000 24.38187 ? 102 LEU A CG   1 
ATOM   1222 C CD1  . LEU A 1 98  ? 19.61100 10.43400 37.13600  1.000 25.41094 ? 102 LEU A CD1  1 
ATOM   1223 C CD2  . LEU A 1 98  ? 18.79900 12.07600 35.43400  1.000 23.13172 ? 102 LEU A CD2  1 
ATOM   1224 H H    . LEU A 1 98  ? 15.36100 10.77300 37.02900  1.000 29.91000 ? 102 LEU A H    1 
ATOM   1225 H HA   . LEU A 1 98  ? 16.40100 11.15800 34.60600  1.000 30.71000 ? 102 LEU A HA   1 
ATOM   1226 H HB2  . LEU A 1 98  ? 17.22400 9.46600  36.71700  1.000 30.21000 ? 102 LEU A HB2  1 
ATOM   1227 H HB3  . LEU A 1 98  ? 17.99900 9.51200  35.33100  1.000 30.21000 ? 102 LEU A HB3  1 
ATOM   1228 H HG   . LEU A 1 98  ? 17.92500 11.62200 37.18900  1.000 29.27000 ? 102 LEU A HG   1 
ATOM   1229 H HD11 . LEU A 1 98  ? 20.18700 11.11700 37.51400  1.000 30.50000 ? 102 LEU A HD11 1 
ATOM   1230 H HD12 . LEU A 1 98  ? 19.31700 9.82700  37.83300  1.000 30.50000 ? 102 LEU A HD12 1 
ATOM   1231 H HD13 . LEU A 1 98  ? 20.08700 9.94300  36.44800  1.000 30.50000 ? 102 LEU A HD13 1 
ATOM   1232 H HD21 . LEU A 1 98  ? 19.54100 12.61200 35.75500  1.000 27.77000 ? 102 LEU A HD21 1 
ATOM   1233 H HD22 . LEU A 1 98  ? 19.06800 11.57800 34.64600  1.000 27.77000 ? 102 LEU A HD22 1 
ATOM   1234 H HD23 . LEU A 1 98  ? 18.04600 12.64800 35.22100  1.000 27.77000 ? 102 LEU A HD23 1 
ATOM   1235 N N    . VAL A 1 99  ? 15.12600 9.48100  33.35800  1.000 27.36644 ? 103 VAL A N    1 
ATOM   1236 C CA   . VAL A 1 99  ? 14.48600 8.44100  32.56400  1.000 27.67700 ? 103 VAL A CA   1 
ATOM   1237 C C    . VAL A 1 99  ? 15.51400 7.91800  31.56900  1.000 26.27683 ? 103 VAL A C    1 
ATOM   1238 O O    . VAL A 1 99  ? 16.58100 8.52900  31.39700  1.000 25.47148 ? 103 VAL A O    1 
ATOM   1239 C CB   . VAL A 1 99  ? 13.22200 8.99200  31.89200  1.000 28.21917 ? 103 VAL A CB   1 
ATOM   1240 C CG1  . VAL A 1 99  ? 12.14600 9.20900  32.94900  1.000 28.91136 ? 103 VAL A CG1  1 
ATOM   1241 C CG2  . VAL A 1 99  ? 13.53900 10.28800 31.16500  1.000 27.10851 ? 103 VAL A CG2  1 
ATOM   1242 H H    . VAL A 1 99  ? 15.18800 10.23300 32.94500  1.000 32.85000 ? 103 VAL A H    1 
ATOM   1243 H HA   . VAL A 1 99  ? 14.21500 7.69300  33.11900  1.000 33.22000 ? 103 VAL A HA   1 
ATOM   1244 H HB   . VAL A 1 99  ? 12.89000 8.35900  31.23600  1.000 33.87000 ? 103 VAL A HB   1 
ATOM   1245 H HG11 . VAL A 1 99  ? 11.35600 9.57800  32.52400  1.000 34.70000 ? 103 VAL A HG11 1 
ATOM   1246 H HG12 . VAL A 1 99  ? 11.93300 8.35800  33.36200  1.000 34.70000 ? 103 VAL A HG12 1 
ATOM   1247 H HG13 . VAL A 1 99  ? 12.48100 9.82700  33.61700  1.000 34.70000 ? 103 VAL A HG13 1 
ATOM   1248 H HG21 . VAL A 1 99  ? 12.81300 10.49500 30.55600  1.000 32.54000 ? 103 VAL A HG21 1 
ATOM   1249 H HG22 . VAL A 1 99  ? 13.63800 11.00000 31.81600  1.000 32.54000 ? 103 VAL A HG22 1 
ATOM   1250 H HG23 . VAL A 1 99  ? 14.36500 10.17800 30.66800  1.000 32.54000 ? 103 VAL A HG23 1 
ATOM   1251 N N    . PRO A 1 100 ? 15.26900 6.76800  30.94900  1.000 25.71624 ? 104 PRO A N    1 
ATOM   1252 C CA   . PRO A 1 100 ? 16.26600 6.19100  30.04100  1.000 24.94773 ? 104 PRO A CA   1 
ATOM   1253 C C    . PRO A 1 100 ? 16.74700 7.18500  28.99000  1.000 22.65535 ? 104 PRO A C    1 
ATOM   1254 O O    . PRO A 1 100 ? 15.97500 7.97500  28.44500  1.000 23.29490 ? 104 PRO A O    1 
ATOM   1255 C CB   . PRO A 1 100 ? 15.52300 5.00600  29.42100  1.000 26.55318 ? 104 PRO A CB   1 
ATOM   1256 C CG   . PRO A 1 100 ? 14.58600 4.57500  30.52300  1.000 27.45329 ? 104 PRO A CG   1 
ATOM   1257 C CD   . PRO A 1 100 ? 14.12000 5.86500  31.15400  1.000 26.90323 ? 104 PRO A CD   1 
ATOM   1258 H HA   . PRO A 1 100 ? 17.03500 5.87700  30.54100  1.000 29.95000 ? 104 PRO A HA   1 
ATOM   1259 H HB2  . PRO A 1 100 ? 15.03500 5.28900  28.63200  1.000 31.87000 ? 104 PRO A HB2  1 
ATOM   1260 H HB3  . PRO A 1 100 ? 16.14700 4.30000  29.19100  1.000 31.87000 ? 104 PRO A HB3  1 
ATOM   1261 H HG2  . PRO A 1 100 ? 13.84000 4.08100  30.14900  1.000 32.95000 ? 104 PRO A HG2  1 
ATOM   1262 H HG3  . PRO A 1 100 ? 15.06000 4.02400  31.16600  1.000 32.95000 ? 104 PRO A HG3  1 
ATOM   1263 H HD2  . PRO A 1 100 ? 13.32900 6.20400  30.70700  1.000 32.29000 ? 104 PRO A HD2  1 
ATOM   1264 H HD3  . PRO A 1 100 ? 13.94100 5.74300  32.10000  1.000 32.29000 ? 104 PRO A HD3  1 
ATOM   1265 N N    . TRP A 1 101 ? 18.04800 7.11900  28.72000  1.000 21.36572 ? 105 TRP A N    1 
ATOM   1266 C CA   A TRP A 1 101 ? 18.75600 8.03700  27.82700  0.410 19.59709 ? 105 TRP A CA   1 
ATOM   1267 C CA   B TRP A 1 101 ? 18.75200 8.03600  27.82500  0.590 19.92081 ? 105 TRP A CA   1 
ATOM   1268 C C    . TRP A 1 101 ? 18.67800 9.48300  28.33000  1.000 18.98122 ? 105 TRP A C    1 
ATOM   1269 O O    . TRP A 1 101 ? 18.01700 10.35500 27.76300  1.000 18.44432 ? 105 TRP A O    1 
ATOM   1270 C CB   A TRP A 1 101 ? 18.27300 7.91900  26.38200  0.410 19.26020 ? 105 TRP A CB   1 
ATOM   1271 C CB   B TRP A 1 101 ? 18.32100 7.91100  26.35500  0.590 20.52615 ? 105 TRP A CB   1 
ATOM   1272 C CG   A TRP A 1 101 ? 19.17800 8.58500  25.38500  0.410 18.89963 ? 105 TRP A CG   1 
ATOM   1273 C CG   B TRP A 1 101 ? 19.27400 8.68000  25.50100  0.590 21.45784 ? 105 TRP A CG   1 
ATOM   1274 C CD1  A TRP A 1 101 ? 19.27300 9.92300  25.11600  0.410 18.68908 ? 105 TRP A CD1  1 
ATOM   1275 C CD1  B TRP A 1 101 ? 19.03700 9.85400  24.85400  0.590 21.38151 ? 105 TRP A CD1  1 
ATOM   1276 C CD2  A TRP A 1 101 ? 20.09800 7.93500  24.50800  0.410 19.61025 ? 105 TRP A CD2  1 
ATOM   1277 C CD2  B TRP A 1 101 ? 20.64900 8.36200  25.26800  0.590 22.80010 ? 105 TRP A CD2  1 
ATOM   1278 N NE1  A TRP A 1 101 ? 20.18800 10.13800 24.11500  0.410 19.66288 ? 105 TRP A NE1  1 
ATOM   1279 N NE1  B TRP A 1 101 ? 20.17200 10.27300 24.20700  0.590 22.53165 ? 105 TRP A NE1  1 
ATOM   1280 C CE2  A TRP A 1 101 ? 20.71400 8.93300  23.73100  0.410 19.97871 ? 105 TRP A CE2  1 
ATOM   1281 C CE2  B TRP A 1 101 ? 21.17900 9.37500  24.45000  0.590 22.92380 ? 105 TRP A CE2  1 
ATOM   1282 C CE3  A TRP A 1 101 ? 20.46800 6.60600  24.31300  0.410 20.28927 ? 105 TRP A CE3  1 
ATOM   1283 C CE3  B TRP A 1 101 ? 21.47700 7.31100  25.66300  0.590 23.46071 ? 105 TRP A CE3  1 
ATOM   1284 C CZ2  A TRP A 1 101 ? 21.68100 8.64000  22.76700  0.410 20.19453 ? 105 TRP A CZ2  1 
ATOM   1285 C CZ2  B TRP A 1 101 ? 22.49800 9.36200  24.00900  0.590 23.37912 ? 105 TRP A CZ2  1 
ATOM   1286 C CZ3  A TRP A 1 101 ? 21.42100 6.31300  23.35200  0.410 20.58142 ? 105 TRP A CZ3  1 
ATOM   1287 C CZ3  B TRP A 1 101 ? 22.79200 7.30500  25.23100  0.590 24.08973 ? 105 TRP A CZ3  1 
ATOM   1288 C CH2  A TRP A 1 101 ? 22.02100 7.32600  22.59600  0.410 20.69722 ? 105 TRP A CH2  1 
ATOM   1289 C CH2  B TRP A 1 101 ? 23.29000 8.32500  24.41700  0.590 23.88707 ? 105 TRP A CH2  1 
ATOM   1290 H H    A TRP A 1 101 ? 18.56900 6.52400  29.05900  0.410 25.65000 ? 105 TRP A H    1 
ATOM   1291 H H    B TRP A 1 101 ? 18.56900 6.52600  29.06000  0.590 25.65000 ? 105 TRP A H    1 
ATOM   1292 H HA   A TRP A 1 101 ? 19.69000 7.77600  27.84200  0.410 23.53000 ? 105 TRP A HA   1 
ATOM   1293 H HA   B TRP A 1 101 ? 19.68400 7.76700  27.84800  0.590 23.91000 ? 105 TRP A HA   1 
ATOM   1294 H HB2  A TRP A 1 101 ? 18.21500 6.98000  26.14800  0.410 23.12000 ? 105 TRP A HB2  1 
ATOM   1295 H HB2  B TRP A 1 101 ? 18.33500 6.98000  26.08500  0.590 24.64000 ? 105 TRP A HB2  1 
ATOM   1296 H HB3  A TRP A 1 101 ? 17.39800 8.33300  26.31000  0.410 23.12000 ? 105 TRP A HB3  1 
ATOM   1297 H HB3  B TRP A 1 101 ? 17.42900 8.27600  26.24100  0.590 24.64000 ? 105 TRP A HB3  1 
ATOM   1298 H HD1  A TRP A 1 101 ? 18.78900 10.58900 25.54800  0.410 22.44000 ? 105 TRP A HD1  1 
ATOM   1299 H HD1  B TRP A 1 101 ? 18.22500 10.30700 24.85200  0.590 25.67000 ? 105 TRP A HD1  1 
ATOM   1300 H HE1  A TRP A 1 101 ? 20.39600 10.90400 23.78400  0.410 23.60000 ? 105 TRP A HE1  1 
ATOM   1301 H HE1  B TRP A 1 101 ? 20.24100 10.98400 23.72700  0.590 27.05000 ? 105 TRP A HE1  1 
ATOM   1302 H HE3  A TRP A 1 101 ? 20.08300 5.92800  24.81900  0.410 24.35000 ? 105 TRP A HE3  1 
ATOM   1303 H HE3  B TRP A 1 101 ? 21.15300 6.62900  26.20500  0.590 28.16000 ? 105 TRP A HE3  1 
ATOM   1304 H HZ2  A TRP A 1 101 ? 22.07900 9.31200  22.26100  0.410 24.24000 ? 105 TRP A HZ2  1 
ATOM   1305 H HZ2  B TRP A 1 101 ? 22.82900 10.03400 23.45800  0.590 28.06000 ? 105 TRP A HZ2  1 
ATOM   1306 H HZ3  A TRP A 1 101 ? 21.66700 5.42800  23.20600  0.410 24.70000 ? 105 TRP A HZ3  1 
ATOM   1307 H HZ3  B TRP A 1 101 ? 23.35300 6.60900  25.48700  0.590 28.91000 ? 105 TRP A HZ3  1 
ATOM   1308 H HH2  A TRP A 1 101 ? 22.66500 7.10100  21.96400  0.410 24.85000 ? 105 TRP A HH2  1 
ATOM   1309 H HH2  B TRP A 1 101 ? 24.18000 8.29800  24.14700  0.590 28.67000 ? 105 TRP A HH2  1 
ATOM   1310 N N    . SER A 1 102 ? 19.41400 9.70900  29.41400  1.000 17.25996 ? 106 SER A N    1 
ATOM   1311 C CA   . SER A 1 102 ? 19.63400 11.03200 29.99500  1.000 16.94677 ? 106 SER A CA   1 
ATOM   1312 C C    . SER A 1 102 ? 21.12900 11.18400 30.23200  1.000 17.13100 ? 106 SER A C    1 
ATOM   1313 O O    . SER A 1 102 ? 21.59700 11.28500 31.37500  1.000 16.72569 ? 106 SER A O    1 
ATOM   1314 C CB   . SER A 1 102 ? 18.84000 11.17300 31.28600  1.000 16.74938 ? 106 SER A CB   1 
ATOM   1315 O OG   . SER A 1 102 ? 17.45200 11.17400 31.00400  1.000 17.57579 ? 106 SER A OG   1 
ATOM   1316 H H    . SER A 1 102 ? 19.81400 9.08500  29.85100  1.000 20.72000 ? 106 SER A H    1 
ATOM   1317 H HA   . SER A 1 102 ? 19.33800 11.73400 29.39400  1.000 20.35000 ? 106 SER A HA   1 
ATOM   1318 H HB2  . SER A 1 102 ? 19.04600 10.42700 31.87100  1.000 20.11000 ? 106 SER A HB2  1 
ATOM   1319 H HB3  . SER A 1 102 ? 19.07800 12.00900 31.71700  1.000 20.11000 ? 106 SER A HB3  1 
ATOM   1320 H HG   . SER A 1 102 ? 17.24300 10.47300 30.59000  1.000 21.10000 ? 106 SER A HG   1 
ATOM   1321 N N    . PRO A 1 103 ? 21.91300 11.15600 29.15100  1.000 16.82044 ? 107 PRO A N    1 
ATOM   1322 C CA   . PRO A 1 103 ? 23.36600 10.99000 29.29400  1.000 17.91794 ? 107 PRO A CA   1 
ATOM   1323 C C    . PRO A 1 103 ? 24.06000 12.16800 29.94000  1.000 17.24417 ? 107 PRO A C    1 
ATOM   1324 O O    . PRO A 1 103 ? 25.11400 11.97400 30.56200  1.000 19.44444 ? 107 PRO A O    1 
ATOM   1325 C CB   . PRO A 1 103 ? 23.84800 10.77600 27.84800  1.000 19.16546 ? 107 PRO A CB   1 
ATOM   1326 C CG   . PRO A 1 103 ? 22.78500 11.37000 27.01900  1.000 19.14440 ? 107 PRO A CG   1 
ATOM   1327 C CD   . PRO A 1 103 ? 21.50800 11.10800 27.74100  1.000 17.96531 ? 107 PRO A CD   1 
ATOM   1328 H HA   . PRO A 1 103 ? 23.54700 10.19300 29.81600  1.000 21.51000 ? 107 PRO A HA   1 
ATOM   1329 H HB2  . PRO A 1 103 ? 24.69500 11.22900 27.70900  1.000 23.01000 ? 107 PRO A HB2  1 
ATOM   1330 H HB3  . PRO A 1 103 ? 23.94600 9.82800  27.66600  1.000 23.01000 ? 107 PRO A HB3  1 
ATOM   1331 H HG2  . PRO A 1 103 ? 22.93800 12.32300 26.92600  1.000 22.98000 ? 107 PRO A HG2  1 
ATOM   1332 H HG3  . PRO A 1 103 ? 22.77900 10.94800 26.14600  1.000 22.98000 ? 107 PRO A HG3  1 
ATOM   1333 H HD2  . PRO A 1 103 ? 20.85200 11.79500 27.54500  1.000 21.57000 ? 107 PRO A HD2  1 
ATOM   1334 H HD3  . PRO A 1 103 ? 21.15300 10.23500 27.51200  1.000 21.57000 ? 107 PRO A HD3  1 
ATOM   1335 N N    . ILE A 1 104 ? 23.53900 13.38100 29.78700  1.000 15.62029 ? 108 ILE A N    1 
ATOM   1336 C CA   . ILE A 1 104 ? 24.14800 14.54600 30.42800  1.000 14.51227 ? 108 ILE A CA   1 
ATOM   1337 C C    . ILE A 1 104 ? 23.57700 14.76400 31.81500  1.000 13.97799 ? 108 ILE A C    1 
ATOM   1338 O O    . ILE A 1 104 ? 24.32700 14.90100 32.79200  1.000 14.46489 ? 108 ILE A O    1 
ATOM   1339 C CB   . ILE A 1 104 ? 23.98700 15.81100 29.56100  1.000 15.13603 ? 108 ILE A CB   1 
ATOM   1340 C CG1  . ILE A 1 104 ? 24.47400 15.55400 28.12300  1.000 16.07824 ? 108 ILE A CG1  1 
ATOM   1341 C CG2  . ILE A 1 104 ? 24.68900 17.01600 30.21900  1.000 15.34394 ? 108 ILE A CG2  1 
ATOM   1342 C CD1  . ILE A 1 104 ? 25.93000 15.13600 28.01300  1.000 17.78634 ? 108 ILE A CD1  1 
ATOM   1343 H H    . ILE A 1 104 ? 22.83800 13.55700 29.32000  1.000 18.76000 ? 108 ILE A H    1 
ATOM   1344 H HA   . ILE A 1 104 ? 25.09900 14.37100 30.50600  1.000 17.42000 ? 108 ILE A HA   1 
ATOM   1345 H HB   . ILE A 1 104 ? 23.04400 16.03000 29.50200  1.000 18.17000 ? 108 ILE A HB   1 
ATOM   1346 H HG12 . ILE A 1 104 ? 23.93700 14.84400 27.73800  1.000 19.30000 ? 108 ILE A HG12 1 
ATOM   1347 H HG13 . ILE A 1 104 ? 24.36500 16.36900 27.60900  1.000 19.30000 ? 108 ILE A HG13 1 
ATOM   1348 H HG21 . ILE A 1 104 ? 24.70700 17.75300 29.58900  1.000 18.42000 ? 108 ILE A HG21 1 
ATOM   1349 H HG22 . ILE A 1 104 ? 24.19600 17.27300 31.01400  1.000 18.42000 ? 108 ILE A HG22 1 
ATOM   1350 H HG23 . ILE A 1 104 ? 25.59400 16.76300 30.45800  1.000 18.42000 ? 108 ILE A HG23 1 
ATOM   1351 H HD11 . ILE A 1 104 ? 26.18700 15.12800 27.07800  1.000 21.35000 ? 108 ILE A HD11 1 
ATOM   1352 H HD12 . ILE A 1 104 ? 26.47800 15.77000 28.50100  1.000 21.35000 ? 108 ILE A HD12 1 
ATOM   1353 H HD13 . ILE A 1 104 ? 26.03400 14.24900 28.39300  1.000 21.35000 ? 108 ILE A HD13 1 
ATOM   1354 N N    A SER A 1 105 ? 22.25600 14.79800 31.93600  0.770 14.69913 ? 109 SER A N    1 
ATOM   1355 N N    B SER A 1 105 ? 22.24000 14.79700 31.88400  0.230 13.89903 ? 109 SER A N    1 
ATOM   1356 C CA   A SER A 1 105 ? 21.64000 15.13700 33.21100  0.770 15.73873 ? 109 SER A CA   1 
ATOM   1357 C CA   B SER A 1 105 ? 21.52000 15.02700 33.13500  0.230 14.05168 ? 109 SER A CA   1 
ATOM   1358 C C    A SER A 1 105 ? 21.93700 14.10300 34.29500  0.770 15.32815 ? 109 SER A C    1 
ATOM   1359 C C    B SER A 1 105 ? 22.05600 14.14200 34.24500  0.230 14.23065 ? 109 SER A C    1 
ATOM   1360 O O    A SER A 1 105 ? 21.90000 14.44600 35.48700  0.770 15.26236 ? 109 SER A O    1 
ATOM   1361 O O    B SER A 1 105 ? 22.26000 14.59100 35.38000  0.230 13.79376 ? 109 SER A O    1 
ATOM   1362 C CB   A SER A 1 105 ? 20.13500 15.34900 33.00200  0.770 15.93349 ? 109 SER A CB   1 
ATOM   1363 C CB   B SER A 1 105 ? 20.03100 14.71300 32.93800  0.230 13.59900 ? 109 SER A CB   1 
ATOM   1364 O OG   A SER A 1 105 ? 19.54600 14.20200 32.44200  0.770 15.99929 ? 109 SER A OG   1 
ATOM   1365 O OG   B SER A 1 105 ? 19.37000 15.67700 32.14900  0.230 13.40424 ? 109 SER A OG   1 
ATOM   1366 H H    A SER A 1 105 ? 21.70000 14.62900 31.30300  0.770 17.65000 ? 109 SER A H    1 
ATOM   1367 H H    B SER A 1 105 ? 21.71900 14.68700 31.20800  0.230 16.68000 ? 109 SER A H    1 
ATOM   1368 H HA   A SER A 1 105 ? 21.99900 15.97500 33.54200  0.770 18.89000 ? 109 SER A HA   1 
ATOM   1369 H HA   B SER A 1 105 ? 21.62900 15.95900 33.38400  0.230 16.87000 ? 109 SER A HA   1 
ATOM   1370 H HB2  A SER A 1 105 ? 19.71900 15.53200 33.85900  0.770 19.13000 ? 109 SER A HB2  1 
ATOM   1371 H HB2  B SER A 1 105 ? 19.95300 13.85100 32.50000  0.230 16.33000 ? 109 SER A HB2  1 
ATOM   1372 H HB3  A SER A 1 105 ? 20.00100 16.09900 32.40100  0.770 19.13000 ? 109 SER A HB3  1 
ATOM   1373 H HB3  B SER A 1 105 ? 19.60500 14.68200 33.80900  0.230 16.33000 ? 109 SER A HB3  1 
ATOM   1374 H HG   A SER A 1 105 ? 19.85900 14.06300 31.67500  0.770 19.21000 ? 109 SER A HG   1 
ATOM   1375 H HG   B SER A 1 105 ? 18.56100 15.46900 32.05900  0.230 16.09000 ? 109 SER A HG   1 
ATOM   1376 N N    . GLU A 1 106 ? 22.26700 12.86300 33.93400  1.000 15.11760 ? 110 GLU A N    1 
ATOM   1377 C CA   . GLU A 1 106 ? 22.63800 11.90900 34.97300  1.000 16.24405 ? 110 GLU A CA   1 
ATOM   1378 C C    . GLU A 1 106 ? 23.95400 12.28000 35.62600  1.000 16.29143 ? 110 GLU A C    1 
ATOM   1379 O O    . GLU A 1 106 ? 24.18700 11.91700 36.78000  1.000 16.73885 ? 110 GLU A O    1 
ATOM   1380 C CB   . GLU A 1 106 ? 22.66400 10.48900 34.43500  1.000 19.92344 ? 110 GLU A CB   1 
ATOM   1381 C CG   . GLU A 1 106 ? 23.74000 10.21400 33.44500  1.000 24.15816 ? 110 GLU A CG   1 
ATOM   1382 C CD   . GLU A 1 106 ? 23.65900 8.80800  32.87900  1.000 28.20075 ? 110 GLU A CD   1 
ATOM   1383 O OE1  . GLU A 1 106 ? 22.58400 8.17900  32.95800  1.000 29.46406 ? 110 GLU A OE1  1 
ATOM   1384 O OE2  . GLU A 1 106 ? 24.68800 8.33500  32.35400  1.000 30.22731 ? 110 GLU A OE2  1 
ATOM   1385 H H    A GLU A 1 106 ? 22.28300 12.56200 33.12900  0.770 18.15000 ? 110 GLU A H    1 
ATOM   1386 H H    B GLU A 1 106 ? 22.20200 12.52900 33.14400  0.230 18.15000 ? 110 GLU A H    1 
ATOM   1387 H HA   . GLU A 1 106 ? 21.95500 11.92500 35.66100  1.000 19.50000 ? 110 GLU A HA   1 
ATOM   1388 H HB2  . GLU A 1 106 ? 22.79000 9.88000  35.17900  1.000 23.91000 ? 110 GLU A HB2  1 
ATOM   1389 H HB3  . GLU A 1 106 ? 21.81500 10.30900 34.00000  1.000 23.91000 ? 110 GLU A HB3  1 
ATOM   1390 H HG2  . GLU A 1 106 ? 23.66200 10.84000 32.70900  1.000 29.00000 ? 110 GLU A HG2  1 
ATOM   1391 H HG3  . GLU A 1 106 ? 24.60200 10.31500 33.87800  1.000 29.00000 ? 110 GLU A HG3  1 
ATOM   1392 N N    A LYS A 1 107 ? 24.81200 13.01500 34.92000  0.580 15.45448 ? 111 LYS A N    1 
ATOM   1393 N N    B LYS A 1 107 ? 24.81300 13.01300 34.92200  0.420 15.53607 ? 111 LYS A N    1 
ATOM   1394 C CA   A LYS A 1 107 ? 26.10400 13.40800 35.46900  0.580 15.81505 ? 111 LYS A CA   1 
ATOM   1395 C CA   B LYS A 1 107 ? 26.09900 13.40700 35.48100  0.420 15.51502 ? 111 LYS A CA   1 
ATOM   1396 C C    A LYS A 1 107 ? 26.01300 14.60400 36.40900  0.580 14.93074 ? 111 LYS A C    1 
ATOM   1397 C C    B LYS A 1 107 ? 25.99700 14.58300 36.44000  0.420 14.83599 ? 111 LYS A C    1 
ATOM   1398 O O    A LYS A 1 107 ? 26.98800 14.89900 37.10900  0.580 14.71229 ? 111 LYS A O    1 
ATOM   1399 O O    B LYS A 1 107 ? 26.95000 14.84500 37.17800  0.420 14.40173 ? 111 LYS A O    1 
ATOM   1400 C CB   A LYS A 1 107 ? 27.07000 13.75800 34.33600  0.580 17.13363 ? 111 LYS A CB   1 
ATOM   1401 C CB   B LYS A 1 107 ? 27.06700 13.77400 34.35700  0.420 16.24142 ? 111 LYS A CB   1 
ATOM   1402 C CG   A LYS A 1 107 ? 27.13900 12.73700 33.19700  0.580 19.91028 ? 111 LYS A CG   1 
ATOM   1403 C CG   B LYS A 1 107 ? 27.23000 12.69700 33.29500  0.420 17.92057 ? 111 LYS A CG   1 
ATOM   1404 C CD   A LYS A 1 107 ? 27.24600 11.30800 33.67100  0.580 22.60534 ? 111 LYS A CD   1 
ATOM   1405 C CD   B LYS A 1 107 ? 27.51600 11.33700 33.88900  0.420 20.22611 ? 111 LYS A CD   1 
ATOM   1406 C CE   A LYS A 1 107 ? 27.72000 10.36400 32.55800  0.580 23.43176 ? 111 LYS A CE   1 
ATOM   1407 C CE   B LYS A 1 107 ? 27.60000 10.26800 32.80500  0.420 21.28676 ? 111 LYS A CE   1 
ATOM   1408 N NZ   A LYS A 1 107 ? 26.69700 10.09600 31.50300  0.580 23.57125 ? 111 LYS A NZ   1 
ATOM   1409 N NZ   B LYS A 1 107 ? 27.51600 8.89000  33.35600  0.420 21.61312 ? 111 LYS A NZ   1 
ATOM   1410 H H    A LYS A 1 107 ? 24.66700 13.29800 34.12100  0.580 18.55000 ? 111 LYS A H    1 
ATOM   1411 H H    B LYS A 1 107 ? 24.67400 13.29200 34.12000  0.420 18.65000 ? 111 LYS A H    1 
ATOM   1412 H HA   A LYS A 1 107 ? 26.46400 12.65500 35.96300  0.580 18.99000 ? 111 LYS A HA   1 
ATOM   1413 H HA   B LYS A 1 107 ? 26.46400 12.65100 35.96800  0.420 18.63000 ? 111 LYS A HA   1 
ATOM   1414 H HB2  A LYS A 1 107 ? 26.79500 14.60500 33.95000  0.580 20.57000 ? 111 LYS A HB2  1 
ATOM   1415 H HB2  B LYS A 1 107 ? 26.74100 14.57400 33.91600  0.420 19.50000 ? 111 LYS A HB2  1 
ATOM   1416 H HB3  A LYS A 1 107 ? 27.96200 13.83700 34.70900  0.580 20.57000 ? 111 LYS A HB3  1 
ATOM   1417 H HB3  B LYS A 1 107 ? 27.94100 13.94100 34.74200  0.420 19.50000 ? 111 LYS A HB3  1 
ATOM   1418 H HG2  A LYS A 1 107 ? 26.33400 12.81200 32.66100  0.580 23.90000 ? 111 LYS A HG2  1 
ATOM   1419 H HG2  B LYS A 1 107 ? 26.41000 12.63300 32.78000  0.420 21.51000 ? 111 LYS A HG2  1 
ATOM   1420 H HG3  A LYS A 1 107 ? 27.91900 12.92700 32.65300  0.580 23.90000 ? 111 LYS A HG3  1 
ATOM   1421 H HG3  B LYS A 1 107 ? 27.96900 12.93300 32.71400  0.420 21.51000 ? 111 LYS A HG3  1 
ATOM   1422 H HD2  A LYS A 1 107 ? 27.88400 11.26000 34.40000  0.580 27.13000 ? 111 LYS A HD2  1 
ATOM   1423 H HD2  B LYS A 1 107 ? 28.36400 11.36300 34.35900  0.420 24.28000 ? 111 LYS A HD2  1 
ATOM   1424 H HD3  A LYS A 1 107 ? 26.37400 11.00600 33.97300  0.580 27.13000 ? 111 LYS A HD3  1 
ATOM   1425 H HD3  B LYS A 1 107 ? 26.80400 11.09600 34.50100  0.420 24.28000 ? 111 LYS A HD3  1 
ATOM   1426 H HE2  A LYS A 1 107 ? 28.49200 10.75900 32.12400  0.580 28.13000 ? 111 LYS A HE2  1 
ATOM   1427 H HE2  B LYS A 1 107 ? 26.86600 10.38900 32.18300  0.420 25.55000 ? 111 LYS A HE2  1 
ATOM   1428 H HE3  A LYS A 1 107 ? 27.96200 9.51200  32.95500  0.580 28.13000 ? 111 LYS A HE3  1 
ATOM   1429 H HE3  B LYS A 1 107 ? 28.44700 10.35400 32.33900  0.420 25.55000 ? 111 LYS A HE3  1 
ATOM   1430 H HZ1  A LYS A 1 107 ? 27.02700 9.53800  30.89400  0.580 28.29000 ? 111 LYS A HZ1  1 
ATOM   1431 H HZ1  B LYS A 1 107 ? 27.57600 8.29400  32.69700  0.420 25.95000 ? 111 LYS A HZ1  1 
ATOM   1432 H HZ2  A LYS A 1 107 ? 25.97300 9.72900  31.86800  0.580 28.29000 ? 111 LYS A HZ2  1 
ATOM   1433 H HZ2  B LYS A 1 107 ? 28.18000 8.75100  33.93200  0.420 25.95000 ? 111 LYS A HZ2  1 
ATOM   1434 H HZ3  A LYS A 1 107 ? 26.46600 10.85700 31.10300  0.580 28.29000 ? 111 LYS A HZ3  1 
ATOM   1435 H HZ3  B LYS A 1 107 ? 26.74000 8.77700  33.77600  0.420 25.95000 ? 111 LYS A HZ3  1 
ATOM   1436 N N    . TYR A 1 108 ? 24.86700 15.28400 36.44800  1.000 15.07023 ? 112 TYR A N    1 
ATOM   1437 C CA   . TYR A 1 108 ? 24.67300 16.47200 37.26500  1.000 14.26750 ? 112 TYR A CA   1 
ATOM   1438 C C    . TYR A 1 108 ? 23.50100 16.28600 38.22200  1.000 14.75177 ? 112 TYR A C    1 
ATOM   1439 O O    . TYR A 1 108 ? 22.99300 17.25800 38.78200  1.000 15.60450 ? 112 TYR A O    1 
ATOM   1440 C CB   . TYR A 1 108 ? 24.49000 17.71200 36.39000  1.000 14.69387 ? 112 TYR A CB   1 
ATOM   1441 C CG   . TYR A 1 108 ? 25.68600 18.02700 35.51900  1.000 14.80441 ? 112 TYR A CG   1 
ATOM   1442 C CD1  . TYR A 1 108 ? 25.84000 17.42800 34.27600  1.000 15.03075 ? 112 TYR A CD1  1 
ATOM   1443 C CD2  . TYR A 1 108 ? 26.64900 18.93400 35.93300  1.000 15.30183 ? 112 TYR A CD2  1 
ATOM   1444 C CE1  . TYR A 1 108 ? 26.91800 17.71800 33.46700  1.000 15.84400 ? 112 TYR A CE1  1 
ATOM   1445 C CE2  . TYR A 1 108 ? 27.73900 19.22700 35.13200  1.000 15.07286 ? 112 TYR A CE2  1 
ATOM   1446 C CZ   . TYR A 1 108 ? 27.86900 18.61300 33.88700  1.000 15.20182 ? 112 TYR A CZ   1 
ATOM   1447 O OH   . TYR A 1 108 ? 28.93700 18.88200 33.05700  1.000 15.75978 ? 112 TYR A OH   1 
ATOM   1448 H H    A TYR A 1 108 ? 24.16900 15.06800 35.99500  0.580 18.09000 ? 112 TYR A H    1 
ATOM   1449 H H    B TYR A 1 108 ? 24.17900 15.08400 35.97400  0.420 18.09000 ? 112 TYR A H    1 
ATOM   1450 H HA   . TYR A 1 108 ? 25.46800 16.62900 37.79900  1.000 17.13000 ? 112 TYR A HA   1 
ATOM   1451 H HB2  . TYR A 1 108 ? 23.72800 17.57200 35.80600  1.000 17.64000 ? 112 TYR A HB2  1 
ATOM   1452 H HB3  . TYR A 1 108 ? 24.33200 18.47800 36.96400  1.000 17.64000 ? 112 TYR A HB3  1 
ATOM   1453 H HD1  . TYR A 1 108 ? 25.20300 16.81800 33.98300  1.000 18.05000 ? 112 TYR A HD1  1 
ATOM   1454 H HD2  . TYR A 1 108 ? 26.56100 19.35000 36.76000  1.000 18.37000 ? 112 TYR A HD2  1 
ATOM   1455 H HE1  . TYR A 1 108 ? 26.99900 17.30800 32.63600  1.000 19.02000 ? 112 TYR A HE1  1 
ATOM   1456 H HE2  . TYR A 1 108 ? 28.38200 19.83300 35.42300  1.000 18.09000 ? 112 TYR A HE2  1 
ATOM   1457 H HH   . TYR A 1 108 ? 29.44600 19.44600 33.41700  1.000 18.92000 ? 112 TYR A HH   1 
ATOM   1458 N N    . LEU A 1 109 ? 23.08400 15.03700 38.42700  1.000 15.45712 ? 113 LEU A N    1 
ATOM   1459 C CA   . LEU A 1 109 ? 22.00000 14.74900 39.35700  1.000 16.27300 ? 113 LEU A CA   1 
ATOM   1460 C C    . LEU A 1 109 ? 22.26300 15.37000 40.71900  1.000 16.71253 ? 113 LEU A C    1 
ATOM   1461 O O    . LEU A 1 109 ? 21.36200 15.94900 41.32800  1.000 16.84676 ? 113 LEU A O    1 
ATOM   1462 C CB   . LEU A 1 109 ? 21.86600 13.23600 39.50500  1.000 16.34406 ? 113 LEU A CB   1 
ATOM   1463 C CG   . LEU A 1 109 ? 20.87500 12.77600 40.57500  1.000 17.46788 ? 113 LEU A CG   1 
ATOM   1464 C CD1  . LEU A 1 109 ? 19.43500 13.21500 40.26200  1.000 17.76529 ? 113 LEU A CD1  1 
ATOM   1465 C CD2  . LEU A 1 109 ? 20.94900 11.26400 40.75200  1.000 19.11545 ? 113 LEU A CD2  1 
ATOM   1466 H H    . LEU A 1 109 ? 23.41200 14.34200 38.04100  1.000 18.55000 ? 113 LEU A H    1 
ATOM   1467 H HA   . LEU A 1 109 ? 21.17200 15.11500 39.00900  1.000 19.53000 ? 113 LEU A HA   1 
ATOM   1468 H HB2  . LEU A 1 109 ? 21.57000 12.87000 38.65600  1.000 19.62000 ? 113 LEU A HB2  1 
ATOM   1469 H HB3  . LEU A 1 109 ? 22.73500 12.87300 39.73700  1.000 19.62000 ? 113 LEU A HB3  1 
ATOM   1470 H HG   . LEU A 1 109 ? 21.12000 13.20100 41.41200  1.000 20.97000 ? 113 LEU A HG   1 
ATOM   1471 H HD11 . LEU A 1 109 ? 18.83400 12.81200 40.90800  1.000 21.33000 ? 113 LEU A HD11 1 
ATOM   1472 H HD12 . LEU A 1 109 ? 19.38000 14.18200 40.31700  1.000 21.33000 ? 113 LEU A HD12 1 
ATOM   1473 H HD13 . LEU A 1 109 ? 19.20200 12.92100 39.36700  1.000 21.33000 ? 113 LEU A HD13 1 
ATOM   1474 H HD21 . LEU A 1 109 ? 20.31000 10.99300 41.43000  1.000 22.95000 ? 113 LEU A HD21 1 
ATOM   1475 H HD22 . LEU A 1 109 ? 20.73700 10.83600 39.90800  1.000 22.95000 ? 113 LEU A HD22 1 
ATOM   1476 H HD23 . LEU A 1 109 ? 21.84700 11.02200 41.02900  1.000 22.95000 ? 113 LEU A HD23 1 
ATOM   1477 N N    . THR A 1 110 ? 23.49000 15.25300 41.21300  1.000 16.19405 ? 114 THR A N    1 
ATOM   1478 C CA   . THR A 1 110 ? 23.81400 15.71200 42.55300  1.000 16.07298 ? 114 THR A CA   1 
ATOM   1479 C C    . THR A 1 110 ? 24.10700 17.20200 42.62200  1.000 15.71241 ? 114 THR A C    1 
ATOM   1480 O O    . THR A 1 110 ? 24.38000 17.71300 43.71900  1.000 16.79938 ? 114 THR A O    1 
ATOM   1481 C CB   . THR A 1 110 ? 24.99200 14.90700 43.10200  1.000 16.96519 ? 114 THR A CB   1 
ATOM   1482 O OG1  . THR A 1 110 ? 26.08000 14.99100 42.18200  1.000 16.20984 ? 114 THR A OG1  1 
ATOM   1483 C CG2  . THR A 1 110 ? 24.57100 13.44500 43.34600  1.000 18.35220 ? 114 THR A CG2  1 
ATOM   1484 H H    . THR A 1 110 ? 24.15400 14.91000 40.78800  1.000 19.44000 ? 114 THR A H    1 
ATOM   1485 H HA   . THR A 1 110 ? 23.05300 15.55100 43.13300  1.000 19.30000 ? 114 THR A HA   1 
ATOM   1486 H HB   . THR A 1 110 ? 25.28600 15.26300 43.95500  1.000 20.37000 ? 114 THR A HB   1 
ATOM   1487 H HG1  . THR A 1 110 ? 25.88000 14.60300 41.46400  1.000 19.46000 ? 114 THR A HG1  1 
ATOM   1488 H HG21 . THR A 1 110 ? 25.32900 12.93000 43.66200  1.000 22.03000 ? 114 THR A HG21 1 
ATOM   1489 H HG22 . THR A 1 110 ? 23.86700 13.41000 44.01200  1.000 22.03000 ? 114 THR A HG22 1 
ATOM   1490 H HG23 . THR A 1 110 ? 24.24400 13.05200 42.52200  1.000 22.03000 ? 114 THR A HG23 1 
ATOM   1491 N N    . THR A 1 111 ? 24.12700 17.90400 41.49100  1.000 15.30447 ? 115 THR A N    1 
ATOM   1492 C CA   . THR A 1 111 ? 24.45700 19.32300 41.48100  1.000 15.37553 ? 115 THR A CA   1 
ATOM   1493 C C    . THR A 1 111 ? 23.37200 20.21900 40.91300  1.000 15.37026 ? 115 THR A C    1 
ATOM   1494 O O    . THR A 1 111 ? 23.33200 21.40100 41.25500  1.000 16.42829 ? 115 THR A O    1 
ATOM   1495 C CB   . THR A 1 111 ? 25.75300 19.60600 40.68600  1.000 14.86494 ? 115 THR A CB   1 
ATOM   1496 O OG1  . THR A 1 111 ? 25.59500 19.26100 39.30200  1.000 15.15708 ? 115 THR A OG1  1 
ATOM   1497 C CG2  . THR A 1 111 ? 26.91200 18.81500 41.22100  1.000 16.38354 ? 115 THR A CG2  1 
ATOM   1498 H H    . THR A 1 111 ? 23.95200 17.57700 40.71500  1.000 18.37000 ? 115 THR A H    1 
ATOM   1499 H HA   . THR A 1 111 ? 24.61200 19.57600 42.40500  1.000 18.46000 ? 115 THR A HA   1 
ATOM   1500 H HB   . THR A 1 111 ? 25.94200 20.55300 40.77200  1.000 17.85000 ? 115 THR A HB   1 
ATOM   1501 H HG1  . THR A 1 111 ? 24.97400 19.71400 38.96200  1.000 18.20000 ? 115 THR A HG1  1 
ATOM   1502 H HG21 . THR A 1 111 ? 27.71300 19.01500 40.71200  1.000 19.67000 ? 115 THR A HG21 1 
ATOM   1503 H HG22 . THR A 1 111 ? 27.06600 19.04100 42.15200  1.000 19.67000 ? 115 THR A HG22 1 
ATOM   1504 H HG23 . THR A 1 111 ? 26.72500 17.86600 41.15500  1.000 19.67000 ? 115 THR A HG23 1 
ATOM   1505 N N    . GLY A 1 112 ? 22.53800 19.71100 40.01000  1.000 14.39120 ? 116 GLY A N    1 
ATOM   1506 C CA   . GLY A 1 112 ? 21.68500 20.54300 39.19000  1.000 15.51765 ? 116 GLY A CA   1 
ATOM   1507 C C    . GLY A 1 112 ? 22.41600 21.02800 37.95400  1.000 14.61754 ? 116 GLY A C    1 
ATOM   1508 O O    . GLY A 1 112 ? 23.63000 20.88200 37.80900  1.000 14.73598 ? 116 GLY A O    1 
ATOM   1509 H H    . GLY A 1 112 ? 22.45000 18.86900 39.85600  1.000 17.28000 ? 116 GLY A H    1 
ATOM   1510 H HA2  . GLY A 1 112 ? 20.90600 20.03600 38.91100  1.000 18.63000 ? 116 GLY A HA2  1 
ATOM   1511 H HA3  . GLY A 1 112 ? 21.39300 21.31400 39.70100  1.000 18.63000 ? 116 GLY A HA3  1 
ATOM   1512 N N    . MET A 1 113 ? 21.63100 21.60300 37.03600  1.000 14.68597 ? 117 MET A N    1 
ATOM   1513 C CA   . MET A 1 113 ? 22.11800 22.19500 35.79000  1.000 14.64649 ? 117 MET A CA   1 
ATOM   1514 C C    . MET A 1 113 ? 21.31300 23.46000 35.50700  1.000 15.53607 ? 117 MET A C    1 
ATOM   1515 O O    . MET A 1 113 ? 20.17700 23.60200 35.96900  1.000 16.37302 ? 117 MET A O    1 
ATOM   1516 C CB   . MET A 1 113 ? 21.95200 21.24200 34.59000  1.000 15.73873 ? 117 MET A CB   1 
ATOM   1517 C CG   . MET A 1 113 ? 22.60000 19.88700 34.73300  1.000 17.70475 ? 117 MET A CG   1 
ATOM   1518 S SD   . MET A 1 113 ? 22.14900 18.73900 33.41000  1.000 21.92368 ? 117 MET A SD   1 
ATOM   1519 C CE   . MET A 1 113 ? 22.53300 19.66300 31.93900  1.000 22.65008 ? 117 MET A CE   1 
ATOM   1520 H H    . MET A 1 113 ? 20.77700 21.66400 37.11700  1.000 17.63000 ? 117 MET A H    1 
ATOM   1521 H HA   . MET A 1 113 ? 23.06000 22.40200 35.89700  1.000 17.58000 ? 117 MET A HA   1 
ATOM   1522 H HB2  . MET A 1 113 ? 21.00400 21.09400 34.44900  1.000 18.89000 ? 117 MET A HB2  1 
ATOM   1523 H HB3  . MET A 1 113 ? 22.34100 21.66600 33.80900  1.000 18.89000 ? 117 MET A HB3  1 
ATOM   1524 H HG2  . MET A 1 113 ? 23.56400 19.99600 34.71700  1.000 21.26000 ? 117 MET A HG2  1 
ATOM   1525 H HG3  . MET A 1 113 ? 22.32500 19.49400 35.57600  1.000 21.26000 ? 117 MET A HG3  1 
ATOM   1526 H HE1  . MET A 1 113 ? 22.45100 19.07900 31.16900  1.000 27.19000 ? 117 MET A HE1  1 
ATOM   1527 H HE2  . MET A 1 113 ? 21.91100 20.40400 31.86000  1.000 27.19000 ? 117 MET A HE2  1 
ATOM   1528 H HE3  . MET A 1 113 ? 23.44000 19.99900 32.00400  1.000 27.19000 ? 117 MET A HE3  1 
ATOM   1529 N N    . THR A 1 114 ? 21.88000 24.36700 34.71400  1.000 14.49121 ? 118 THR A N    1 
ATOM   1530 C CA   . THR A 1 114 ? 21.11800 25.55400 34.36800  1.000 14.79388 ? 118 THR A CA   1 
ATOM   1531 C C    . THR A 1 114 ? 20.14600 25.24700 33.22400  1.000 14.59649 ? 118 THR A C    1 
ATOM   1532 O O    . THR A 1 114 ? 20.27900 24.25700 32.49900  1.000 14.39383 ? 118 THR A O    1 
ATOM   1533 C CB   . THR A 1 114 ? 22.01000 26.70500 33.92400  1.000 15.67556 ? 118 THR A CB   1 
ATOM   1534 O OG1  . THR A 1 114 ? 22.61500 26.35800 32.66900  1.000 15.48607 ? 118 THR A OG1  1 
ATOM   1535 C CG2  . THR A 1 114 ? 23.07400 27.02500 34.98200  1.000 16.05719 ? 118 THR A CG2  1 
ATOM   1536 H H    . THR A 1 114 ? 22.67000 24.31700 34.37900  1.000 17.40000 ? 118 THR A H    1 
ATOM   1537 H HA   . THR A 1 114 ? 20.63300 25.83200 35.16100  1.000 17.76000 ? 118 THR A HA   1 
ATOM   1538 H HB   . THR A 1 114 ? 21.48500 27.51300 33.81100  1.000 18.82000 ? 118 THR A HB   1 
ATOM   1539 H HG1  . THR A 1 114 ? 23.11700 26.98000 32.41000  1.000 18.59000 ? 118 THR A HG1  1 
ATOM   1540 H HG21 . THR A 1 114 ? 23.62000 27.77100 34.68800  1.000 19.28000 ? 118 THR A HG21 1 
ATOM   1541 H HG22 . THR A 1 114 ? 22.64700 27.25900 35.82100  1.000 19.28000 ? 118 THR A HG22 1 
ATOM   1542 H HG23 . THR A 1 114 ? 23.64400 26.25400 35.12300  1.000 19.28000 ? 118 THR A HG23 1 
ATOM   1543 N N    . VAL A 1 115 ? 19.16900 26.13800 33.06000  1.000 14.41225 ? 119 VAL A N    1 
ATOM   1544 C CA   . VAL A 1 115 ? 18.22200 26.03300 31.95200  1.000 14.27013 ? 119 VAL A CA   1 
ATOM   1545 C C    . VAL A 1 115 ? 18.96000 25.95900 30.62400  1.000 15.18603 ? 119 VAL A C    1 
ATOM   1546 O O    . VAL A 1 115 ? 18.61800 25.14400 29.75900  1.000 15.05444 ? 119 VAL A O    1 
ATOM   1547 C CB   . VAL A 1 115 ? 17.21300 27.19300 32.02000  1.000 15.07549 ? 119 VAL A CB   1 
ATOM   1548 C CG1  . VAL A 1 115 ? 16.41100 27.27600 30.72400  1.000 15.96770 ? 119 VAL A CG1  1 
ATOM   1549 C CG2  . VAL A 1 115 ? 16.29000 27.01800 33.22600  1.000 16.33617 ? 119 VAL A CG2  1 
ATOM   1550 H H    . VAL A 1 115 ? 19.03200 26.81300 33.57500  1.000 17.30000 ? 119 VAL A H    1 
ATOM   1551 H HA   . VAL A 1 115 ? 17.71800 25.20800 32.03400  1.000 17.13000 ? 119 VAL A HA   1 
ATOM   1552 H HB   . VAL A 1 115 ? 17.69200 28.03000 32.12700  1.000 18.10000 ? 119 VAL A HB   1 
ATOM   1553 H HG11 . VAL A 1 115 ? 15.65600 27.87000 30.85700  1.000 19.17000 ? 119 VAL A HG11 1 
ATOM   1554 H HG12 . VAL A 1 115 ? 16.98300 27.62100 30.02100  1.000 19.17000 ? 119 VAL A HG12 1 
ATOM   1555 H HG13 . VAL A 1 115 ? 16.09700 26.38800 30.49000  1.000 19.17000 ? 119 VAL A HG13 1 
ATOM   1556 H HG21 . VAL A 1 115 ? 15.65300 27.75000 33.24500  1.000 19.61000 ? 119 VAL A HG21 1 
ATOM   1557 H HG22 . VAL A 1 115 ? 15.82000 26.17400 33.14400  1.000 19.61000 ? 119 VAL A HG22 1 
ATOM   1558 H HG23 . VAL A 1 115 ? 16.82400 27.02300 34.03500  1.000 19.61000 ? 119 VAL A HG23 1 
ATOM   1559 N N    . ALA A 1 116 ? 20.00000 26.78100 30.45000  1.000 15.05444 ? 120 ALA A N    1 
ATOM   1560 C CA   . ALA A 1 116 ? 20.75600 26.73000 29.20300  1.000 15.53871 ? 120 ALA A CA   1 
ATOM   1561 C C    . ALA A 1 116 ? 21.44100 25.38400 29.02900  1.000 14.96758 ? 120 ALA A C    1 
ATOM   1562 O O    . ALA A 1 116 ? 21.46800 24.82900 27.91900  1.000 15.11497 ? 120 ALA A O    1 
ATOM   1563 C CB   . ALA A 1 116 ? 21.77700 27.86300 29.16100  1.000 16.44408 ? 120 ALA A CB   1 
ATOM   1564 H H    . ALA A 1 116 ? 20.27800 27.35900 31.02300  1.000 18.07000 ? 120 ALA A H    1 
ATOM   1565 H HA   . ALA A 1 116 ? 20.14300 26.85200 28.46200  1.000 18.66000 ? 120 ALA A HA   1 
ATOM   1566 H HB1  . ALA A 1 116 ? 22.31900 27.77000 28.36200  1.000 19.74000 ? 120 ALA A HB1  1 
ATOM   1567 H HB2  . ALA A 1 116 ? 21.30600 28.71100 29.14500  1.000 19.74000 ? 120 ALA A HB2  1 
ATOM   1568 H HB3  . ALA A 1 116 ? 22.33900 27.81100 29.95000  1.000 19.74000 ? 120 ALA A HB3  1 
ATOM   1569 N N    . GLU A 1 117 ? 22.03600 24.85700 30.10400  1.000 14.68860 ? 121 GLU A N    1 
ATOM   1570 C CA   . GLU A 1 117 ? 22.67700 23.55100 30.02100  1.000 14.26224 ? 121 GLU A CA   1 
ATOM   1571 C C    . GLU A 1 117 ? 21.67600 22.45900 29.68700  1.000 14.38857 ? 121 GLU A C    1 
ATOM   1572 O O    . GLU A 1 117 ? 21.97400 21.54600 28.91200  1.000 14.57280 ? 121 GLU A O    1 
ATOM   1573 C CB   . GLU A 1 117 ? 23.40400 23.23600 31.32800  1.000 15.07023 ? 121 GLU A CB   1 
ATOM   1574 C CG   . GLU A 1 117 ? 24.65300 24.05600 31.53000  1.000 16.21773 ? 121 GLU A CG   1 
ATOM   1575 C CD   . GLU A 1 117 ? 25.33600 23.72400 32.84200  1.000 17.27049 ? 121 GLU A CD   1 
ATOM   1576 O OE1  . GLU A 1 117 ? 24.66000 23.69100 33.89200  1.000 16.77570 ? 121 GLU A OE1  1 
ATOM   1577 O OE2  . GLU A 1 117 ? 26.54300 23.45200 32.82400  1.000 19.21283 ? 121 GLU A OE2  1 
ATOM   1578 H H    . GLU A 1 117 ? 22.08000 25.23100 30.87700  1.000 17.63000 ? 121 GLU A H    1 
ATOM   1579 H HA   . GLU A 1 117 ? 23.33700 23.57600 29.31100  1.000 17.13000 ? 121 GLU A HA   1 
ATOM   1580 H HB2  . GLU A 1 117 ? 22.80600 23.41600 32.07000  1.000 18.09000 ? 121 GLU A HB2  1 
ATOM   1581 H HB3  . GLU A 1 117 ? 23.65900 22.30000 31.32700  1.000 18.09000 ? 121 GLU A HB3  1 
ATOM   1582 H HG2  . GLU A 1 117 ? 25.27600 23.87500 30.80900  1.000 19.47000 ? 121 GLU A HG2  1 
ATOM   1583 H HG3  . GLU A 1 117 ? 24.42000 24.99800 31.53800  1.000 19.47000 ? 121 GLU A HG3  1 
ATOM   1584 N N    . LEU A 1 118 ? 20.49500 22.50600 30.29700  1.000 14.29645 ? 122 LEU A N    1 
ATOM   1585 C CA   . LEU A 1 118 ? 19.47500 21.51700 29.97100  1.000 13.70164 ? 122 LEU A CA   1 
ATOM   1586 C C    . LEU A 1 118 ? 19.05800 21.62200 28.51900  1.000 14.40699 ? 122 LEU A C    1 
ATOM   1587 O O    . LEU A 1 118 ? 18.83700 20.60100 27.87000  1.000 14.51753 ? 122 LEU A O    1 
ATOM   1588 C CB   . LEU A 1 118 ? 18.25600 21.70400 30.87400  1.000 15.28604 ? 122 LEU A CB   1 
ATOM   1589 C CG   . LEU A 1 118 ? 18.47200 21.37500 32.34900  1.000 16.75727 ? 122 LEU A CG   1 
ATOM   1590 C CD1  . LEU A 1 118 ? 17.29700 21.89900 33.13700  1.000 17.66264 ? 122 LEU A CD1  1 
ATOM   1591 C CD2  . LEU A 1 118 ? 18.62300 19.87300 32.55200  1.000 17.45999 ? 122 LEU A CD2  1 
ATOM   1592 H H    . LEU A 1 118 ? 20.26400 23.08500 30.88900  1.000 17.16000 ? 122 LEU A H    1 
ATOM   1593 H HA   . LEU A 1 118 ? 19.84200 20.63300 30.12500  1.000 16.45000 ? 122 LEU A HA   1 
ATOM   1594 H HB2  . LEU A 1 118 ? 17.97900 22.63200 30.82300  1.000 18.35000 ? 122 LEU A HB2  1 
ATOM   1595 H HB3  . LEU A 1 118 ? 17.54700 21.12700 30.55100  1.000 18.35000 ? 122 LEU A HB3  1 
ATOM   1596 H HG   . LEU A 1 118 ? 19.28700 21.79200 32.66800  1.000 20.12000 ? 122 LEU A HG   1 
ATOM   1597 H HD11 . LEU A 1 118 ? 17.42200 21.68100 34.07300  1.000 21.20000 ? 122 LEU A HD11 1 
ATOM   1598 H HD12 . LEU A 1 118 ? 17.24700 22.86100 33.02500  1.000 21.20000 ? 122 LEU A HD12 1 
ATOM   1599 H HD13 . LEU A 1 118 ? 16.48500 21.48500 32.80600  1.000 21.20000 ? 122 LEU A HD13 1 
ATOM   1600 H HD21 . LEU A 1 118 ? 18.76800 19.69400 33.49400  1.000 20.96000 ? 122 LEU A HD21 1 
ATOM   1601 H HD22 . LEU A 1 118 ? 17.81300 19.43100 32.25300  1.000 20.96000 ? 122 LEU A HD22 1 
ATOM   1602 H HD23 . LEU A 1 118 ? 19.38200 19.55900 32.03500  1.000 20.96000 ? 122 LEU A HD23 1 
ATOM   1603 N N    . SER A 1 119 ? 18.94700 22.85000 28.01100  1.000 14.73861 ? 123 SER A N    1 
ATOM   1604 C CA   . SER A 1 119 ? 18.55100 23.04900 26.61600  1.000 14.46489 ? 123 SER A CA   1 
ATOM   1605 C C    . SER A 1 119 ? 19.60600 22.48500 25.66900  1.000 14.14643 ? 123 SER A C    1 
ATOM   1606 O O    . SER A 1 119 ? 19.28600 21.77700 24.70400  1.000 14.84389 ? 123 SER A O    1 
ATOM   1607 C CB   . SER A 1 119 ? 18.35000 24.54100 26.36200  1.000 15.07286 ? 123 SER A CB   1 
ATOM   1608 O OG   . SER A 1 119 ? 17.30000 25.08800 27.14300  1.000 15.86506 ? 123 SER A OG   1 
ATOM   1609 H H    . SER A 1 119 ? 19.09300 23.57600 28.44700  1.000 17.69000 ? 123 SER A H    1 
ATOM   1610 H HA   . SER A 1 119 ? 17.71500 22.58800 26.44600  1.000 17.37000 ? 123 SER A HA   1 
ATOM   1611 H HB2  . SER A 1 119 ? 19.17200 25.00600 26.58100  1.000 18.10000 ? 123 SER A HB2  1 
ATOM   1612 H HB3  . SER A 1 119 ? 18.13600 24.66900 25.42400  1.000 18.10000 ? 123 SER A HB3  1 
ATOM   1613 H HG   . SER A 1 119 ? 17.47600 25.00400 27.96000  1.000 19.05000 ? 123 SER A HG   1 
ATOM   1614 N N    . ALA A 1 120 ? 20.87800 22.77800 25.94300  1.000 14.80441 ? 124 ALA A N    1 
ATOM   1615 C CA   . ALA A 1 120 ? 21.95300 22.21800 25.12500  1.000 15.07549 ? 124 ALA A CA   1 
ATOM   1616 C C    . ALA A 1 120 ? 21.94500 20.69300 25.16100  1.000 14.45436 ? 124 ALA A C    1 
ATOM   1617 O O    . ALA A 1 120 ? 22.14800 20.03900 24.13200  1.000 15.17287 ? 124 ALA A O    1 
ATOM   1618 C CB   . ALA A 1 120 ? 23.30000 22.75900 25.60100  1.000 16.59936 ? 124 ALA A CB   1 
ATOM   1619 H H    . ALA A 1 120 ? 21.14100 23.28800 26.58300  1.000 17.77000 ? 124 ALA A H    1 
ATOM   1620 H HA   . ALA A 1 120 ? 21.82100 22.49400 24.20500  1.000 18.10000 ? 124 ALA A HA   1 
ATOM   1621 H HB1  . ALA A 1 120 ? 24.00400 22.37700 25.05400  1.000 19.93000 ? 124 ALA A HB1  1 
ATOM   1622 H HB2  . ALA A 1 120 ? 23.30100 23.72500 25.51500  1.000 19.93000 ? 124 ALA A HB2  1 
ATOM   1623 H HB3  . ALA A 1 120 ? 23.43000 22.50900 26.52900  1.000 19.93000 ? 124 ALA A HB3  1 
ATOM   1624 N N    . ALA A 1 121 ? 21.72200 20.10100 26.33800  1.000 13.44635 ? 125 ALA A N    1 
ATOM   1625 C CA   . ALA A 1 121 ? 21.70600 18.64900 26.44100  1.000 13.55952 ? 125 ALA A CA   1 
ATOM   1626 C C    . ALA A 1 121 ? 20.53300 18.04900 25.67000  1.000 13.26738 ? 125 ALA A C    1 
ATOM   1627 O O    . ALA A 1 121 ? 20.67900 17.00500 25.02100  1.000 13.46477 ? 125 ALA A O    1 
ATOM   1628 C CB   . ALA A 1 121 ? 21.64600 18.21700 27.91900  1.000 14.33856 ? 125 ALA A CB   1 
ATOM   1629 H H    . ALA A 1 121 ? 21.58000 20.51500 27.07800  1.000 16.15000 ? 125 ALA A H    1 
ATOM   1630 H HA   . ALA A 1 121 ? 22.53000 18.30800 26.05900  1.000 16.28000 ? 125 ALA A HA   1 
ATOM   1631 H HB1  . ALA A 1 121 ? 21.64600 17.24800 27.96400  1.000 17.21000 ? 125 ALA A HB1  1 
ATOM   1632 H HB2  . ALA A 1 121 ? 22.42200 18.56900 28.38300  1.000 17.21000 ? 125 ALA A HB2  1 
ATOM   1633 H HB3  . ALA A 1 121 ? 20.83500 18.56700 28.31800  1.000 17.21000 ? 125 ALA A HB3  1 
ATOM   1634 N N    . ALA A 1 122 ? 19.34900 18.65800 25.79100  1.000 13.74112 ? 126 ALA A N    1 
ATOM   1635 C CA   . ALA A 1 122 ? 18.17900 18.22400 25.03500  1.000 13.86482 ? 126 ALA A CA   1 
ATOM   1636 C C    . ALA A 1 122 ? 18.43800 18.26900 23.53400  1.000 13.33581 ? 126 ALA A C    1 
ATOM   1637 O O    . ALA A 1 122 ? 18.05100 17.33300 22.81800  1.000 14.11485 ? 126 ALA A O    1 
ATOM   1638 C CB   . ALA A 1 122 ? 16.98200 19.09800 25.43000  1.000 13.19895 ? 126 ALA A CB   1 
ATOM   1639 H H    . ALA A 1 122 ? 19.19800 19.32900 26.30700  1.000 16.50000 ? 126 ALA A H    1 
ATOM   1640 H HA   . ALA A 1 122 ? 17.96700 17.30300 25.25500  1.000 16.65000 ? 126 ALA A HA   1 
ATOM   1641 H HB1  . ALA A 1 122 ? 16.20900 18.82600 24.91200  1.000 15.85000 ? 126 ALA A HB1  1 
ATOM   1642 H HB2  . ALA A 1 122 ? 16.80500 18.98000 26.37700  1.000 15.85000 ? 126 ALA A HB2  1 
ATOM   1643 H HB3  . ALA A 1 122 ? 17.19500 20.02600 25.24600  1.000 15.85000 ? 126 ALA A HB3  1 
ATOM   1644 N N    . VAL A 1 123 ? 19.08900 19.32700 23.03700  1.000 13.34107 ? 127 VAL A N    1 
ATOM   1645 C CA   . VAL A 1 123 ? 19.35200 19.42700 21.59600  1.000 12.96471 ? 127 VAL A CA   1 
ATOM   1646 C C    . VAL A 1 123 ? 20.47900 18.49500 21.17100  1.000 13.67006 ? 127 VAL A C    1 
ATOM   1647 O O    . VAL A 1 123 ? 20.36300 17.78500 20.16600  1.000 14.53859 ? 127 VAL A O    1 
ATOM   1648 C CB   . VAL A 1 123 ? 19.64300 20.88200 21.19000  1.000 13.96220 ? 127 VAL A CB   1 
ATOM   1649 C CG1  . VAL A 1 123 ? 20.04700 20.97600 19.68700  1.000 14.44384 ? 127 VAL A CG1  1 
ATOM   1650 C CG2  . VAL A 1 123 ? 18.46500 21.77900 21.47100  1.000 14.03853 ? 127 VAL A CG2  1 
ATOM   1651 H H    . VAL A 1 123 ? 19.38300 19.98700 23.50200  1.000 16.02000 ? 127 VAL A H    1 
ATOM   1652 H HA   . VAL A 1 123 ? 18.54700 19.14500 21.13400  1.000 15.57000 ? 127 VAL A HA   1 
ATOM   1653 H HB   . VAL A 1 123 ? 20.38900 21.19200 21.72600  1.000 16.76000 ? 127 VAL A HB   1 
ATOM   1654 H HG11 . VAL A 1 123 ? 20.03000 21.90700 19.41300  1.000 17.34000 ? 127 VAL A HG11 1 
ATOM   1655 H HG12 . VAL A 1 123 ? 20.94000 20.61500 19.57600  1.000 17.34000 ? 127 VAL A HG12 1 
ATOM   1656 H HG13 . VAL A 1 123 ? 19.41500 20.46500 19.15700  1.000 17.34000 ? 127 VAL A HG13 1 
ATOM   1657 H HG21 . VAL A 1 123 ? 18.68300 22.68200 21.19300  1.000 16.85000 ? 127 VAL A HG21 1 
ATOM   1658 H HG22 . VAL A 1 123 ? 17.69700 21.45600 20.97300  1.000 16.85000 ? 127 VAL A HG22 1 
ATOM   1659 H HG23 . VAL A 1 123 ? 18.27400 21.76100 22.42100  1.000 16.85000 ? 127 VAL A HG23 1 
ATOM   1660 N N    . GLN A 1 124 ? 21.59400 18.52800 21.88700  1.000 13.75691 ? 128 GLN A N    1 
ATOM   1661 C CA   . GLN A 1 124 ? 22.84100 17.95900 21.38200  1.000 14.25171 ? 128 GLN A CA   1 
ATOM   1662 C C    . GLN A 1 124 ? 23.05600 16.50300 21.74300  1.000 13.97799 ? 128 GLN A C    1 
ATOM   1663 O O    . GLN A 1 124 ? 23.83900 15.81900 21.06400  1.000 13.99905 ? 128 GLN A O    1 
ATOM   1664 C CB   . GLN A 1 124 ? 24.02000 18.79800 21.87000  1.000 15.64924 ? 128 GLN A CB   1 
ATOM   1665 C CG   . GLN A 1 124 ? 23.93000 20.23000 21.42300  1.000 15.67030 ? 128 GLN A CG   1 
ATOM   1666 C CD   . GLN A 1 124 ? 25.06100 21.09100 21.92600  1.000 17.13363 ? 128 GLN A CD   1 
ATOM   1667 O OE1  . GLN A 1 124 ? 25.59300 20.87700 23.02900  1.000 20.23664 ? 128 GLN A OE1  1 
ATOM   1668 N NE2  . GLN A 1 124 ? 25.46200 22.06200 21.12100  1.000 18.08112 ? 128 GLN A NE2  1 
ATOM   1669 H H    . GLN A 1 124 ? 21.65800 18.87400 22.67100  1.000 16.51000 ? 128 GLN A H    1 
ATOM   1670 H HA   . GLN A 1 124 ? 22.82200 17.99400 20.41300  1.000 17.11000 ? 128 GLN A HA   1 
ATOM   1671 H HB2  . GLN A 1 124 ? 24.03800 18.78600 22.84000  1.000 18.79000 ? 128 GLN A HB2  1 
ATOM   1672 H HB3  . GLN A 1 124 ? 24.84200 18.42400 21.51800  1.000 18.79000 ? 128 GLN A HB3  1 
ATOM   1673 H HG2  . GLN A 1 124 ? 23.94600 20.25600 20.45300  1.000 18.81000 ? 128 GLN A HG2  1 
ATOM   1674 H HG3  . GLN A 1 124 ? 23.10000 20.60900 21.75100  1.000 18.81000 ? 128 GLN A HG3  1 
ATOM   1675 H HE21 . GLN A 1 124 ? 25.08100 22.17300 20.35800  1.000 21.71000 ? 128 GLN A HE21 1 
ATOM   1676 H HE22 . GLN A 1 124 ? 26.10300 22.58200 21.36100  1.000 21.71000 ? 128 GLN A HE22 1 
ATOM   1677 N N    . TYR A 1 125 ? 22.36400 16.01800 22.77300  1.000 14.20697 ? 129 TYR A N    1 
ATOM   1678 C CA   . TYR A 1 125 ? 22.42200 14.62800 23.18900  1.000 14.43594 ? 129 TYR A CA   1 
ATOM   1679 C C    . TYR A 1 125 ? 21.04000 13.99600 23.24900  1.000 14.85441 ? 129 TYR A C    1 
ATOM   1680 O O    . TYR A 1 125 ? 20.92900 12.81800 23.58400  1.000 16.04929 ? 129 TYR A O    1 
ATOM   1681 C CB   . TYR A 1 125 ? 23.10900 14.50400 24.57300  1.000 14.18065 ? 129 TYR A CB   1 
ATOM   1682 C CG   . TYR A 1 125 ? 24.55000 14.88600 24.48300  1.000 15.74662 ? 129 TYR A CG   1 
ATOM   1683 C CD1  . TYR A 1 125 ? 24.94200 16.21700 24.56100  1.000 17.11258 ? 129 TYR A CD1  1 
ATOM   1684 C CD2  . TYR A 1 125 ? 25.52100 13.93200 24.27000  1.000 17.53894 ? 129 TYR A CD2  1 
ATOM   1685 C CE1  . TYR A 1 125 ? 26.27200 16.58300 24.44900  1.000 18.63118 ? 129 TYR A CE1  1 
ATOM   1686 C CE2  . TYR A 1 125 ? 26.85800 14.28600 24.15900  1.000 17.96005 ? 129 TYR A CE2  1 
ATOM   1687 C CZ   . TYR A 1 125 ? 27.22400 15.61400 24.24500  1.000 18.97859 ? 129 TYR A CZ   1 
ATOM   1688 O OH   . TYR A 1 125 ? 28.55500 15.97900 24.12800  1.000 22.72641 ? 129 TYR A OH   1 
ATOM   1689 H H    . TYR A 1 125 ? 21.83900 16.49400 23.26000  1.000 17.05000 ? 129 TYR A H    1 
ATOM   1690 H HA   . TYR A 1 125 ? 22.96200 14.12300 22.56100  1.000 17.33000 ? 129 TYR A HA   1 
ATOM   1691 H HB2  . TYR A 1 125 ? 22.67200 15.09500 25.20500  1.000 17.02000 ? 129 TYR A HB2  1 
ATOM   1692 H HB3  . TYR A 1 125 ? 23.05100 13.58700 24.88200  1.000 17.02000 ? 129 TYR A HB3  1 
ATOM   1693 H HD1  . TYR A 1 125 ? 24.29800 16.87500 24.69200  1.000 20.54000 ? 129 TYR A HD1  1 
ATOM   1694 H HD2  . TYR A 1 125 ? 25.27700 13.03700 24.20000  1.000 21.06000 ? 129 TYR A HD2  1 
ATOM   1695 H HE1  . TYR A 1 125 ? 26.51900 17.47800 24.51100  1.000 22.36000 ? 129 TYR A HE1  1 
ATOM   1696 H HE2  . TYR A 1 125 ? 27.50500 13.63100 24.02700  1.000 21.56000 ? 129 TYR A HE2  1 
ATOM   1697 H HH   . TYR A 1 125 ? 29.02400 15.30400 23.95800  1.000 27.28000 ? 129 TYR A HH   1 
ATOM   1698 N N    . SER A 1 126 ? 19.99200 14.73700 22.90800  1.000 14.39909 ? 130 SER A N    1 
ATOM   1699 C CA   . SER A 1 126 ? 18.62100 14.25500 23.02300  1.000 14.75440 ? 130 SER A CA   1 
ATOM   1700 C C    . SER A 1 126 ? 18.31800 13.78000 24.44200  1.000 15.57818 ? 130 SER A C    1 
ATOM   1701 O O    . SER A 1 126 ? 17.67900 12.75700 24.64700  1.000 16.52830 ? 130 SER A O    1 
ATOM   1702 C CB   . SER A 1 126 ? 18.32600 13.15800 22.01000  1.000 14.60701 ? 130 SER A CB   1 
ATOM   1703 O OG   . SER A 1 126 ? 16.98700 13.28100 21.54700  1.000 13.88324 ? 130 SER A OG   1 
ATOM   1704 H H    . SER A 1 126 ? 20.05000 15.53900 22.60100  1.000 17.29000 ? 130 SER A H    1 
ATOM   1705 H HA   . SER A 1 126 ? 18.02700 14.99700 22.83200  1.000 17.71000 ? 130 SER A HA   1 
ATOM   1706 H HB2  . SER A 1 126 ? 18.93300 13.24500 21.25800  1.000 17.54000 ? 130 SER A HB2  1 
ATOM   1707 H HB3  . SER A 1 126 ? 18.44100 12.29300 22.43200  1.000 17.54000 ? 130 SER A HB3  1 
ATOM   1708 H HG   . SER A 1 126 ? 16.80000 14.08900 21.41900  1.000 16.67000 ? 130 SER A HG   1 
ATOM   1709 N N    . ASP A 1 127 ? 18.84000 14.50200 25.43000  1.000 15.18077 ? 131 ASP A N    1 
ATOM   1710 C CA   . ASP A 1 127 ? 18.70500 14.10300 26.83300  1.000 14.26487 ? 131 ASP A CA   1 
ATOM   1711 C C    . ASP A 1 127 ? 17.24400 14.16700 27.25600  1.000 15.37026 ? 131 ASP A C    1 
ATOM   1712 O O    . ASP A 1 127 ? 16.61700 15.23100 27.21200  1.000 15.24656 ? 131 ASP A O    1 
ATOM   1713 C CB   . ASP A 1 127 ? 19.56100 15.04500 27.65800  1.000 14.52016 ? 131 ASP A CB   1 
ATOM   1714 C CG   . ASP A 1 127 ? 19.73500 14.60400 29.10000  1.000 15.39395 ? 131 ASP A CG   1 
ATOM   1715 O OD1  . ASP A 1 127 ? 18.73300 14.58300 29.84000  1.000 14.74387 ? 131 ASP A OD1  1 
ATOM   1716 O OD2  . ASP A 1 127 ? 20.87800 14.31300 29.47800  1.000 15.66504 ? 131 ASP A OD2  1 
ATOM   1717 H H    . ASP A 1 127 ? 19.28000 15.23200 25.31600  1.000 18.23000 ? 131 ASP A H    1 
ATOM   1718 H HA   . ASP A 1 127 ? 18.99800 13.18800 26.97100  1.000 17.12000 ? 131 ASP A HA   1 
ATOM   1719 H HB2  . ASP A 1 127 ? 20.44200 15.09900 27.25600  1.000 17.43000 ? 131 ASP A HB2  1 
ATOM   1720 H HB3  . ASP A 1 127 ? 19.14400 15.92100 27.66400  1.000 17.43000 ? 131 ASP A HB3  1 
ATOM   1721 N N    . ASN A 1 128 ? 16.71300 13.01600 27.67900  1.000 15.04128 ? 132 ASN A N    1 
ATOM   1722 C CA   . ASN A 1 128 ? 15.28800 12.90000 27.96500  1.000 15.65188 ? 132 ASN A CA   1 
ATOM   1723 C C    . ASN A 1 128 ? 14.89000 13.60100 29.25800  1.000 15.47291 ? 132 ASN A C    1 
ATOM   1724 O O    . ASN A 1 128 ? 13.89200 14.33300 29.29100  1.000 15.76242 ? 132 ASN A O    1 
ATOM   1725 C CB   . ASN A 1 128 ? 14.88400 11.44000 27.99000  1.000 16.68884 ? 132 ASN A CB   1 
ATOM   1726 C CG   . ASN A 1 128 ? 14.67700 10.89200 26.60100  1.000 17.25207 ? 132 ASN A CG   1 
ATOM   1727 O OD1  . ASN A 1 128 ? 14.17400 11.59200 25.71100  1.000 18.43905 ? 132 ASN A OD1  1 
ATOM   1728 N ND2  . ASN A 1 128 ? 15.07100 9.66300  26.39300  1.000 18.09164 ? 132 ASN A ND2  1 
ATOM   1729 H H    . ASN A 1 128 ? 17.15700 12.29100 27.80700  1.000 18.06000 ? 132 ASN A H    1 
ATOM   1730 H HA   . ASN A 1 128 ? 14.80400 13.34000 27.24900  1.000 18.79000 ? 132 ASN A HA   1 
ATOM   1731 H HB2  . ASN A 1 128 ? 15.58200 10.92200 28.42000  1.000 20.03000 ? 132 ASN A HB2  1 
ATOM   1732 H HB3  . ASN A 1 128 ? 14.05200 11.34700 28.48000  1.000 20.03000 ? 132 ASN A HB3  1 
ATOM   1733 H HD21 . ASN A 1 128 ? 14.97400 9.30600  25.61700  1.000 21.72000 ? 132 ASN A HD21 1 
ATOM   1734 H HD22 . ASN A 1 128 ? 15.42700 9.21100  27.03300  1.000 21.72000 ? 132 ASN A HD22 1 
ATOM   1735 N N    . ALA A 1 129 ? 15.64800 13.39500 30.33400  1.000 15.32026 ? 133 ALA A N    1 
ATOM   1736 C CA   . ALA A 1 129 ? 15.33300 14.10300 31.56700  1.000 15.86506 ? 133 ALA A CA   1 
ATOM   1737 C C    . ALA A 1 129 ? 15.37800 15.60800 31.35400  1.000 15.31236 ? 133 ALA A C    1 
ATOM   1738 O O    . ALA A 1 129 ? 14.50100 16.33900 31.84300  1.000 16.23879 ? 133 ALA A O    1 
ATOM   1739 C CB   . ALA A 1 129 ? 16.28400 13.68100 32.68400  1.000 16.18089 ? 133 ALA A CB   1 
ATOM   1740 H H    . ALA A 1 129 ? 16.32600 12.86800 30.37300  1.000 18.39000 ? 133 ALA A H    1 
ATOM   1741 H HA   . ALA A 1 129 ? 14.43600 13.86400 31.84600  1.000 19.04000 ? 133 ALA A HA   1 
ATOM   1742 H HB1  . ALA A 1 129 ? 16.08900 14.20200 33.47800  1.000 19.43000 ? 133 ALA A HB1  1 
ATOM   1743 H HB2  . ALA A 1 129 ? 16.15600 12.73700 32.86800  1.000 19.43000 ? 133 ALA A HB2  1 
ATOM   1744 H HB3  . ALA A 1 129 ? 17.19700 13.84200 32.39900  1.000 19.43000 ? 133 ALA A HB3  1 
ATOM   1745 N N    . ALA A 1 130 ? 16.38100 16.09200 30.60700  1.000 14.40699 ? 134 ALA A N    1 
ATOM   1746 C CA   . ALA A 1 130 ? 16.48400 17.52400 30.36800  1.000 14.68860 ? 134 ALA A CA   1 
ATOM   1747 C C    . ALA A 1 130 ? 15.26100 18.02300 29.62100  1.000 15.41501 ? 134 ALA A C    1 
ATOM   1748 O O    . ALA A 1 130 ? 14.69900 19.07400 29.95300  1.000 16.06245 ? 134 ALA A O    1 
ATOM   1749 C CB   . ALA A 1 130 ? 17.74300 17.86800 29.56900  1.000 14.98864 ? 134 ALA A CB   1 
ATOM   1750 H H    . ALA A 1 130 ? 16.99700 15.61800 30.23800  1.000 17.30000 ? 134 ALA A H    1 
ATOM   1751 H HA   . ALA A 1 130 ? 16.55000 17.96800 31.22800  1.000 17.63000 ? 134 ALA A HA   1 
ATOM   1752 H HB1  . ALA A 1 130 ? 17.77200 18.82600 29.42300  1.000 17.99000 ? 134 ALA A HB1  1 
ATOM   1753 H HB2  . ALA A 1 130 ? 18.52300 17.58600 30.07200  1.000 17.99000 ? 134 ALA A HB2  1 
ATOM   1754 H HB3  . ALA A 1 130 ? 17.71400 17.40400 28.71800  1.000 17.99000 ? 134 ALA A HB3  1 
ATOM   1755 N N    . ALA A 1 131 ? 14.83700 17.27600 28.59700  1.000 15.15182 ? 135 ALA A N    1 
ATOM   1756 C CA   . ALA A 1 131 ? 13.67100 17.68100 27.83200  1.000 15.67820 ? 135 ALA A CA   1 
ATOM   1757 C C    . ALA A 1 131 ? 12.41600 17.74600 28.71200  1.000 16.44408 ? 135 ALA A C    1 
ATOM   1758 O O    . ALA A 1 131 ? 11.61900 18.68600 28.57500  1.000 16.21773 ? 135 ALA A O    1 
ATOM   1759 C CB   . ALA A 1 131 ? 13.44400 16.71500 26.66900  1.000 16.18615 ? 135 ALA A CB   1 
ATOM   1760 H H    . ALA A 1 131 ? 15.20500 16.54500 28.33300  1.000 18.19000 ? 135 ALA A H    1 
ATOM   1761 H HA   . ALA A 1 131 ? 13.83500 18.56600 27.47000  1.000 18.82000 ? 135 ALA A HA   1 
ATOM   1762 H HB1  . ALA A 1 131 ? 12.66300 17.00100 26.16900  1.000 19.43000 ? 135 ALA A HB1  1 
ATOM   1763 H HB2  . ALA A 1 131 ? 14.22600 16.72400 26.09400  1.000 19.43000 ? 135 ALA A HB2  1 
ATOM   1764 H HB3  . ALA A 1 131 ? 13.30300 15.82300 27.02200  1.000 19.43000 ? 135 ALA A HB3  1 
ATOM   1765 N N    A ASN A 1 132 ? 12.21500 16.75300 29.59400  0.430 16.82044 ? 136 ASN A N    1 
ATOM   1766 N N    B ASN A 1 132 ? 12.21800 16.75700 29.59300  0.570 16.70463 ? 136 ASN A N    1 
ATOM   1767 C CA   A ASN A 1 132 ? 11.04700 16.75500 30.43800  0.430 18.30483 ? 136 ASN A CA   1 
ATOM   1768 C CA   B ASN A 1 132 ? 11.05300 16.75300 30.44400  0.570 18.14428 ? 136 ASN A CA   1 
ATOM   1769 C C    A ASN A 1 132 ? 11.06300 17.92500 31.40100  0.430 16.78886 ? 136 ASN A C    1 
ATOM   1770 C C    B ASN A 1 132 ? 11.06300 17.92700 31.40300  0.570 16.67568 ? 136 ASN A C    1 
ATOM   1771 O O    A ASN A 1 132 ? 10.02400 18.57000 31.63400  0.430 17.07836 ? 136 ASN A O    1 
ATOM   1772 O O    B ASN A 1 132 ? 10.02600 18.57500 31.63600  0.570 17.07310 ? 136 ASN A O    1 
ATOM   1773 C CB   A ASN A 1 132 ? 10.94000 15.43000 31.22100  0.430 22.17898 ? 136 ASN A CB   1 
ATOM   1774 C CB   B ASN A 1 132 ? 10.96300 15.43400 31.22400  0.570 22.02369 ? 136 ASN A CB   1 
ATOM   1775 C CG   A ASN A 1 132 ? 10.92300 14.21000 30.31100  0.430 26.01628 ? 136 ASN A CG   1 
ATOM   1776 C CG   B ASN A 1 132 ? 10.33500 14.32000 30.41800  0.570 26.46896 ? 136 ASN A CG   1 
ATOM   1777 O OD1  A ASN A 1 132 ? 10.60900 14.29600 29.12300  0.430 26.54002 ? 136 ASN A OD1  1 
ATOM   1778 O OD1  B ASN A 1 132 ? 9.43600  14.54900 29.60800  0.570 27.42960 ? 136 ASN A OD1  1 
ATOM   1779 N ND2  A ASN A 1 132 ? 11.25800 13.04900 30.88400  0.430 26.82690 ? 136 ASN A ND2  1 
ATOM   1780 N ND2  B ASN A 1 132 ? 10.82400 13.09100 30.62100  0.570 28.55342 ? 136 ASN A ND2  1 
ATOM   1781 H H    A ASN A 1 132 ? 12.74100 16.08200 29.71000  0.430 20.19000 ? 136 ASN A H    1 
ATOM   1782 H H    B ASN A 1 132 ? 12.74600 16.08800 29.70700  0.570 20.05000 ? 136 ASN A H    1 
ATOM   1783 H HA   A ASN A 1 132 ? 10.26500 16.83400 29.86900  0.430 21.97000 ? 136 ASN A HA   1 
ATOM   1784 H HA   B ASN A 1 132 ? 10.26600 16.82500 29.88100  0.570 21.78000 ? 136 ASN A HA   1 
ATOM   1785 H HB2  A ASN A 1 132 ? 11.70200 15.35000 31.81500  0.430 26.62000 ? 136 ASN A HB2  1 
ATOM   1786 H HB2  B ASN A 1 132 ? 11.85700 15.15500 31.47700  0.570 26.44000 ? 136 ASN A HB2  1 
ATOM   1787 H HB3  A ASN A 1 132 ? 10.11700 15.43200 31.73500  0.430 26.62000 ? 136 ASN A HB3  1 
ATOM   1788 H HB3  B ASN A 1 132 ? 10.42200 15.57200 32.01700  0.570 26.44000 ? 136 ASN A HB3  1 
ATOM   1789 H HD21 A ASN A 1 132 ? 11.26600 12.32600 30.41800  0.430 32.20000 ? 136 ASN A HD21 1 
ATOM   1790 H HD21 B ASN A 1 132 ? 11.46100 12.97000 31.18600  0.570 34.27000 ? 136 ASN A HD21 1 
ATOM   1791 H HD22 A ASN A 1 132 ? 11.46500 13.02500 31.71800  0.430 32.20000 ? 136 ASN A HD22 1 
ATOM   1792 H HD22 B ASN A 1 132 ? 10.50100 12.42300 30.18700  0.570 34.27000 ? 136 ASN A HD22 1 
ATOM   1793 N N    . LEU A 1 133 ? 12.22900 18.24900 31.95100  1.000 16.23616 ? 137 LEU A N    1 
ATOM   1794 C CA   . LEU A 1 133 ? 12.31500 19.40100 32.85500  1.000 16.47829 ? 137 LEU A CA   1 
ATOM   1795 C C    . LEU A 1 133 ? 11.98500 20.69300 32.12800  1.000 17.16522 ? 137 LEU A C    1 
ATOM   1796 O O    . LEU A 1 133 ? 11.27400 21.54200 32.65800  1.000 18.72593 ? 137 LEU A O    1 
ATOM   1797 C CB   . LEU A 1 133 ? 13.72400 19.46100 33.46500  1.000 17.23101 ? 137 LEU A CB   1 
ATOM   1798 C CG   . LEU A 1 133 ? 14.04900 18.37200 34.48200  1.000 17.68633 ? 137 LEU A CG   1 
ATOM   1799 C CD1  . LEU A 1 133 ? 15.54300 18.31800 34.72300  1.000 18.77857 ? 137 LEU A CD1  1 
ATOM   1800 C CD2  . LEU A 1 133 ? 13.30100 18.63600 35.78300  1.000 19.54445 ? 137 LEU A CD2  1 
ATOM   1801 H H    . LEU A 1 133 ? 12.96700 17.82800 31.82000  1.000 19.49000 ? 137 LEU A H    1 
ATOM   1802 H HA   . LEU A 1 133 ? 11.67400 19.29800 33.57500  1.000 19.78000 ? 137 LEU A HA   1 
ATOM   1803 H HB2  . LEU A 1 133 ? 14.37000 19.38600 32.74600  1.000 20.69000 ? 137 LEU A HB2  1 
ATOM   1804 H HB3  . LEU A 1 133 ? 13.82500 20.31500 33.91400  1.000 20.69000 ? 137 LEU A HB3  1 
ATOM   1805 H HG   . LEU A 1 133 ? 13.76600 17.50900 34.14200  1.000 21.23000 ? 137 LEU A HG   1 
ATOM   1806 H HD11 . LEU A 1 133 ? 15.73400 17.62000 35.36900  1.000 22.54000 ? 137 LEU A HD11 1 
ATOM   1807 H HD12 . LEU A 1 133 ? 15.99100 18.12500 33.88500  1.000 22.54000 ? 137 LEU A HD12 1 
ATOM   1808 H HD13 . LEU A 1 133 ? 15.83900 19.17600 35.06700  1.000 22.54000 ? 137 LEU A HD13 1 
ATOM   1809 H HD21 . LEU A 1 133 ? 13.56600 17.97300 36.43900  1.000 23.46000 ? 137 LEU A HD21 1 
ATOM   1810 H HD22 . LEU A 1 133 ? 13.52500 19.52400 36.10200  1.000 23.46000 ? 137 LEU A HD22 1 
ATOM   1811 H HD23 . LEU A 1 133 ? 12.34800 18.57500 35.61700  1.000 23.46000 ? 137 LEU A HD23 1 
ATOM   1812 N N    . LEU A 1 134 ? 12.47000 20.84900 30.89600  1.000 16.19142 ? 138 LEU A N    1 
ATOM   1813 C CA   . LEU A 1 134 ? 12.18100 22.07400 30.16200  1.000 16.30459 ? 138 LEU A CA   1 
ATOM   1814 C C    . LEU A 1 134 ? 10.72700 22.12500 29.71900  1.000 17.16258 ? 138 LEU A C    1 
ATOM   1815 O O    . LEU A 1 134 ? 10.11800 23.19900 29.72100  1.000 17.48631 ? 138 LEU A O    1 
ATOM   1816 C CB   . LEU A 1 134 ? 13.09700 22.16200 28.95300  1.000 17.18890 ? 138 LEU A CB   1 
ATOM   1817 C CG   . LEU A 1 134 ? 14.57400 22.35800 29.31200  1.000 16.76517 ? 138 LEU A CG   1 
ATOM   1818 C CD1  . LEU A 1 134 ? 15.41900 22.17400 28.06700  1.000 16.43881 ? 138 LEU A CD1  1 
ATOM   1819 C CD2  . LEU A 1 134 ? 14.80800 23.71500 29.93300  1.000 17.62843 ? 138 LEU A CD2  1 
ATOM   1820 H H    . LEU A 1 134 ? 12.95600 20.27600 30.47700  1.000 19.44000 ? 138 LEU A H    1 
ATOM   1821 H HA   . LEU A 1 134 ? 12.34500 22.83600 30.74000  1.000 19.57000 ? 138 LEU A HA   1 
ATOM   1822 H HB2  . LEU A 1 134 ? 13.02200 21.33900 28.44500  1.000 20.64000 ? 138 LEU A HB2  1 
ATOM   1823 H HB3  . LEU A 1 134 ? 12.82200 22.91500 28.40800  1.000 20.64000 ? 138 LEU A HB3  1 
ATOM   1824 H HG   . LEU A 1 134 ? 14.84000 21.69800 29.97200  1.000 20.13000 ? 138 LEU A HG   1 
ATOM   1825 H HD11 . LEU A 1 134 ? 16.35100 22.31500 28.29400  1.000 19.73000 ? 138 LEU A HD11 1 
ATOM   1826 H HD12 . LEU A 1 134 ? 15.29300 21.27300 27.73000  1.000 19.73000 ? 138 LEU A HD12 1 
ATOM   1827 H HD13 . LEU A 1 134 ? 15.14000 22.82000 27.39900  1.000 19.73000 ? 138 LEU A HD13 1 
ATOM   1828 H HD21 . LEU A 1 134 ? 15.76300 23.86100 30.02200  1.000 21.16000 ? 138 LEU A HD21 1 
ATOM   1829 H HD22 . LEU A 1 134 ? 14.42100 24.39500 29.36000  1.000 21.16000 ? 138 LEU A HD22 1 
ATOM   1830 H HD23 . LEU A 1 134 ? 14.38700 23.74000 30.80700  1.000 21.16000 ? 138 LEU A HD23 1 
ATOM   1831 N N    . LEU A 1 135 ? 10.15900 20.98300 29.32200  1.000 16.93624 ? 139 LEU A N    1 
ATOM   1832 C CA   A LEU A 1 135 ? 8.73600  20.93700 28.99000  0.440 17.81266 ? 139 LEU A CA   1 
ATOM   1833 C CA   B LEU A 1 135 ? 8.74300  20.97100 28.97300  0.560 17.35998 ? 139 LEU A CA   1 
ATOM   1834 C C    . LEU A 1 135 ? 7.89300  21.42800 30.15400  1.000 18.88384 ? 139 LEU A C    1 
ATOM   1835 O O    . LEU A 1 135 ? 6.92500  22.16700 29.97000  1.000 19.72342 ? 139 LEU A O    1 
ATOM   1836 C CB   A LEU A 1 135 ? 8.34300  19.49700 28.69400  0.440 18.68119 ? 139 LEU A CB   1 
ATOM   1837 C CB   B LEU A 1 135 ? 8.32800  19.57600 28.50300  0.560 17.48894 ? 139 LEU A CB   1 
ATOM   1838 C CG   A LEU A 1 135 ? 8.25200  19.07400 27.24200  0.440 18.36536 ? 139 LEU A CG   1 
ATOM   1839 C CG   B LEU A 1 135 ? 7.08200  19.44300 27.62900  0.560 15.97823 ? 139 LEU A CG   1 
ATOM   1840 C CD1  A LEU A 1 135 ? 7.99300  17.58000 27.19300  0.440 18.27061 ? 139 LEU A CD1  1 
ATOM   1841 C CD1  B LEU A 1 135 ? 7.15000  20.34200 26.38700  0.560 15.71504 ? 139 LEU A CD1  1 
ATOM   1842 C CD2  A LEU A 1 135 ? 7.15100  19.84800 26.52300  0.440 18.84963 ? 139 LEU A CD2  1 
ATOM   1843 C CD2  B LEU A 1 135 ? 6.92400  17.97100 27.24600  0.560 15.44922 ? 139 LEU A CD2  1 
ATOM   1844 H H    A LEU A 1 135 ? 10.57000 20.23200 29.23900  0.440 20.33000 ? 139 LEU A H    1 
ATOM   1845 H H    B LEU A 1 135 ? 10.56100 20.22600 29.25000  0.560 20.33000 ? 139 LEU A H    1 
ATOM   1846 H HA   A LEU A 1 135 ? 8.57600  21.49600 28.21400  0.440 21.38000 ? 139 LEU A HA   1 
ATOM   1847 H HA   B LEU A 1 135 ? 8.58900  21.58300 28.23700  0.560 20.84000 ? 139 LEU A HA   1 
ATOM   1848 H HB2  A LEU A 1 135 ? 9.00000  18.92000 29.11200  0.440 22.43000 ? 139 LEU A HB2  1 
ATOM   1849 H HB2  B LEU A 1 135 ? 9.06500  19.20900 27.99100  0.560 21.00000 ? 139 LEU A HB2  1 
ATOM   1850 H HB3  A LEU A 1 135 ? 7.46900  19.34400 29.08500  0.440 22.43000 ? 139 LEU A HB3  1 
ATOM   1851 H HB3  B LEU A 1 135 ? 8.17000  19.03600 29.29300  0.560 21.00000 ? 139 LEU A HB3  1 
ATOM   1852 H HG   A LEU A 1 135 ? 9.08200  19.27000 26.77900  0.440 22.05000 ? 139 LEU A HG   1 
ATOM   1853 H HG   B LEU A 1 135 ? 6.30000  19.73700 28.12100  0.560 19.18000 ? 139 LEU A HG   1 
ATOM   1854 H HD11 A LEU A 1 135 ? 7.93900  17.29900 26.26600  0.440 21.93000 ? 139 LEU A HD11 1 
ATOM   1855 H HD11 B LEU A 1 135 ? 6.47700  20.05300 25.75100  0.560 18.86000 ? 139 LEU A HD11 1 
ATOM   1856 H HD12 A LEU A 1 135 ? 8.72200  17.11800 27.63600  0.440 21.93000 ? 139 LEU A HD12 1 
ATOM   1857 H HD12 B LEU A 1 135 ? 6.98200  21.26000 26.65300  0.560 18.86000 ? 139 LEU A HD12 1 
ATOM   1858 H HD13 A LEU A 1 135 ? 7.15700  17.38900 27.64600  0.440 21.93000 ? 139 LEU A HD13 1 
ATOM   1859 H HD13 B LEU A 1 135 ? 8.03300  20.26900 25.99200  0.560 18.86000 ? 139 LEU A HD13 1 
ATOM   1860 H HD21 A LEU A 1 135 ? 6.89800  19.36500 25.72000  0.440 22.63000 ? 139 LEU A HD21 1 
ATOM   1861 H HD21 B LEU A 1 135 ? 6.12800  17.87100 26.70000  0.560 18.55000 ? 139 LEU A HD21 1 
ATOM   1862 H HD22 A LEU A 1 135 ? 6.38600  19.93100 27.11400  0.440 22.63000 ? 139 LEU A HD22 1 
ATOM   1863 H HD22 B LEU A 1 135 ? 7.70600  17.68900 26.74600  0.560 18.55000 ? 139 LEU A HD22 1 
ATOM   1864 H HD23 A LEU A 1 135 ? 7.48500  20.72800 26.28800  0.440 22.63000 ? 139 LEU A HD23 1 
ATOM   1865 H HD23 B LEU A 1 135 ? 6.83900  17.44200 28.05400  0.560 18.55000 ? 139 LEU A HD23 1 
ATOM   1866 N N    . LYS A 1 136 ? 8.24900  21.00700 31.36600  1.000 20.41824 ? 140 LYS A N    1 
ATOM   1867 C CA   . LYS A 1 136 ? 7.52800  21.46800 32.54400  1.000 23.23700 ? 140 LYS A CA   1 
ATOM   1868 C C    . LYS A 1 136 ? 7.61300  22.98300 32.65500  1.000 23.30543 ? 140 LYS A C    1 
ATOM   1869 O O    . LYS A 1 136 ? 6.59900  23.66000 32.86600  1.000 25.52938 ? 140 LYS A O    1 
ATOM   1870 C CB   . LYS A 1 136 ? 8.10600  20.77900 33.78400  1.000 26.12682 ? 140 LYS A CB   1 
ATOM   1871 C CG   . LYS A 1 136 ? 7.50200  21.18500 35.11000  1.000 31.39061 ? 140 LYS A CG   1 
ATOM   1872 C CD   . LYS A 1 136 ? 8.48500  22.04200 35.91700  1.000 34.90682 ? 140 LYS A CD   1 
ATOM   1873 C CE   . LYS A 1 136 ? 9.81800  21.32800 36.18500  1.000 37.08076 ? 140 LYS A CE   1 
ATOM   1874 N NZ   . LYS A 1 136 ? 10.97300 21.87800 35.38700  1.000 37.18867 ? 140 LYS A NZ   1 
ATOM   1875 H H    . LYS A 1 136 ? 8.89500  20.46200 31.53000  1.000 24.51000 ? 140 LYS A H    1 
ATOM   1876 H HA   . LYS A 1 136 ? 6.59000  21.23000 32.48400  1.000 27.89000 ? 140 LYS A HA   1 
ATOM   1877 H HB2  . LYS A 1 136 ? 7.97300  19.82300 33.68900  1.000 31.36000 ? 140 LYS A HB2  1 
ATOM   1878 H HB3  . LYS A 1 136 ? 9.05400  20.97900 33.82800  1.000 31.36000 ? 140 LYS A HB3  1 
ATOM   1879 H HG2  . LYS A 1 136 ? 6.69700  21.70400 34.95400  1.000 37.67000 ? 140 LYS A HG2  1 
ATOM   1880 H HG3  . LYS A 1 136 ? 7.29000  20.39200 35.62600  1.000 37.67000 ? 140 LYS A HG3  1 
ATOM   1881 H HD2  . LYS A 1 136 ? 8.67500  22.85500 35.42300  1.000 41.89000 ? 140 LYS A HD2  1 
ATOM   1882 H HD3  . LYS A 1 136 ? 8.08500  22.26000 36.77300  1.000 41.89000 ? 140 LYS A HD3  1 
ATOM   1883 H HE2  . LYS A 1 136 ? 10.03800 21.41900 37.12500  1.000 44.51000 ? 140 LYS A HE2  1 
ATOM   1884 H HE3  . LYS A 1 136 ? 9.72100  20.39000 35.95600  1.000 44.51000 ? 140 LYS A HE3  1 
ATOM   1885 H HZ1  . LYS A 1 136 ? 11.71600 21.42600 35.57500  1.000 44.63000 ? 140 LYS A HZ1  1 
ATOM   1886 H HZ2  . LYS A 1 136 ? 10.80400 21.80500 34.51600  1.000 44.63000 ? 140 LYS A HZ2  1 
ATOM   1887 H HZ3  . LYS A 1 136 ? 11.09900 22.73600 35.58500  1.000 44.63000 ? 140 LYS A HZ3  1 
ATOM   1888 N N    . GLU A 1 137 ? 8.81000  23.53700 32.45900  1.000 22.66061 ? 141 GLU A N    1 
ATOM   1889 C CA   . GLU A 1 137 ? 8.99300  24.97900 32.56900  1.000 25.23197 ? 141 GLU A CA   1 
ATOM   1890 C C    . GLU A 1 137 ? 8.09200  25.73900 31.61200  1.000 24.96352 ? 141 GLU A C    1 
ATOM   1891 O O    . GLU A 1 137 ? 7.62200  26.83600 31.93100  1.000 25.98733 ? 141 GLU A O    1 
ATOM   1892 C CB   . GLU A 1 137 ? 10.44900 25.34500 32.28800  1.000 28.70344 ? 141 GLU A CB   1 
ATOM   1893 C CG   . GLU A 1 137 ? 11.38300 25.02600 33.40700  1.000 33.19345 ? 141 GLU A CG   1 
ATOM   1894 C CD   . GLU A 1 137 ? 11.05200 25.81500 34.64100  1.000 36.15433 ? 141 GLU A CD   1 
ATOM   1895 O OE1  . GLU A 1 137 ? 10.92700 27.06100 34.53300  1.000 37.72558 ? 141 GLU A OE1  1 
ATOM   1896 O OE2  . GLU A 1 137 ? 10.88300 25.18200 35.70500  1.000 37.11761 ? 141 GLU A OE2  1 
ATOM   1897 H H    . GLU A 1 137 ? 9.52500  23.10200 32.26200  1.000 27.20000 ? 141 GLU A H    1 
ATOM   1898 H HA   . GLU A 1 137 ? 8.76800  25.24000 33.47600  1.000 30.29000 ? 141 GLU A HA   1 
ATOM   1899 H HB2  . GLU A 1 137 ? 10.74700 24.85400 31.50600  1.000 34.45000 ? 141 GLU A HB2  1 
ATOM   1900 H HB3  . GLU A 1 137 ? 10.50300 26.29900 32.12100  1.000 34.45000 ? 141 GLU A HB3  1 
ATOM   1901 H HG2  . GLU A 1 137 ? 11.31700 24.08200 33.62100  1.000 39.84000 ? 141 GLU A HG2  1 
ATOM   1902 H HG3  . GLU A 1 137 ? 12.29000 25.24300 33.14000  1.000 39.84000 ? 141 GLU A HG3  1 
ATOM   1903 N N    . LEU A 1 138 ? 7.86800  25.19300 30.42100  1.000 23.59757 ? 142 LEU A N    1 
ATOM   1904 C CA   . LEU A 1 138 ? 7.11400  25.89800 29.39000  1.000 23.72390 ? 142 LEU A CA   1 
ATOM   1905 C C    . LEU A 1 138 ? 5.60900  25.67600 29.46600  1.000 23.01329 ? 142 LEU A C    1 
ATOM   1906 O O    . LEU A 1 138 ? 4.88500  26.13500 28.57600  1.000 25.26356 ? 142 LEU A O    1 
ATOM   1907 C CB   . LEU A 1 138 ? 7.56100  25.45500 28.00200  1.000 26.26104 ? 142 LEU A CB   1 
ATOM   1908 C CG   . LEU A 1 138 ? 8.87700  25.95200 27.42500  1.000 28.75608 ? 142 LEU A CG   1 
ATOM   1909 C CD1  . LEU A 1 138 ? 9.01200  25.40500 26.00200  1.000 30.27731 ? 142 LEU A CD1  1 
ATOM   1910 C CD2  . LEU A 1 138 ? 8.96400  27.44400 27.41800  1.000 29.70356 ? 142 LEU A CD2  1 
ATOM   1911 H H    . LEU A 1 138 ? 8.14300  24.41300 30.18600  1.000 28.32000 ? 142 LEU A H    1 
ATOM   1912 H HA   . LEU A 1 138 ? 7.29900  26.84300 29.50600  1.000 28.48000 ? 142 LEU A HA   1 
ATOM   1913 H HB2  . LEU A 1 138 ? 7.62400  24.48700 28.01800  1.000 31.52000 ? 142 LEU A HB2  1 
ATOM   1914 H HB3  . LEU A 1 138 ? 6.87300  25.73200 27.37800  1.000 31.52000 ? 142 LEU A HB3  1 
ATOM   1915 H HG   . LEU A 1 138 ? 9.60800  25.63900 27.98000  1.000 34.51000 ? 142 LEU A HG   1 
ATOM   1916 H HD11 . LEU A 1 138 ? 9.95200  25.38200 25.76100  1.000 36.34000 ? 142 LEU A HD11 1 
ATOM   1917 H HD12 . LEU A 1 138 ? 8.64100  24.51000 25.97100  1.000 36.34000 ? 142 LEU A HD12 1 
ATOM   1918 H HD13 . LEU A 1 138 ? 8.52900  25.98500 25.39400  1.000 36.34000 ? 142 LEU A HD13 1 
ATOM   1919 H HD21 . LEU A 1 138 ? 9.75900  27.71100 26.93000  1.000 35.65000 ? 142 LEU A HD21 1 
ATOM   1920 H HD22 . LEU A 1 138 ? 8.17400  27.80400 26.98500  1.000 35.65000 ? 142 LEU A HD22 1 
ATOM   1921 H HD23 . LEU A 1 138 ? 9.01400  27.76200 28.33300  1.000 35.65000 ? 142 LEU A HD23 1 
ATOM   1922 N N    . GLY A 1 139 ? 5.12100  24.94000 30.45300  1.000 21.71839 ? 143 GLY A N    1 
ATOM   1923 C CA   . GLY A 1 139 ? 3.70400  24.67400 30.53400  1.000 21.92105 ? 143 GLY A CA   1 
ATOM   1924 C C    . GLY A 1 139 ? 3.25600  23.41700 29.83100  1.000 20.22874 ? 143 GLY A C    1 
ATOM   1925 O O    . GLY A 1 139 ? 2.07300  23.29700 29.49700  1.000 22.56060 ? 143 GLY A O    1 
ATOM   1926 H H    . GLY A 1 139 ? 5.59100  24.58800 31.08100  1.000 26.07000 ? 143 GLY A H    1 
ATOM   1927 H HA2  . GLY A 1 139 ? 3.45500  24.59500 31.46900  1.000 26.31000 ? 143 GLY A HA2  1 
ATOM   1928 H HA3  . GLY A 1 139 ? 3.22400  25.42000 30.14200  1.000 26.31000 ? 143 GLY A HA3  1 
ATOM   1929 N N    . GLY A 1 140 ? 4.16200  22.48100 29.58900  1.000 17.76266 ? 144 GLY A N    1 
ATOM   1930 C CA   . GLY A 1 140 ? 3.82100  21.18600 29.06500  1.000 16.83360 ? 144 GLY A CA   1 
ATOM   1931 C C    . GLY A 1 140 ? 3.64400  21.17100 27.56000  1.000 16.16773 ? 144 GLY A C    1 
ATOM   1932 O O    . GLY A 1 140 ? 3.92800  22.14700 26.85400  1.000 17.13363 ? 144 GLY A O    1 
ATOM   1933 H H    . GLY A 1 140 ? 5.00500  22.58200 29.72600  1.000 21.33000 ? 144 GLY A H    1 
ATOM   1934 H HA2  . GLY A 1 140 ? 4.52300  20.55700 29.29200  1.000 20.21000 ? 144 GLY A HA2  1 
ATOM   1935 H HA3  . GLY A 1 140 ? 2.99000  20.89100 29.46900  1.000 20.21000 ? 144 GLY A HA3  1 
ATOM   1936 N N    . PRO A 1 141 ? 3.17400  20.03800 27.04400  1.000 16.07824 ? 145 PRO A N    1 
ATOM   1937 C CA   . PRO A 1 141 ? 2.93200  19.92300 25.58300  1.000 16.49145 ? 145 PRO A CA   1 
ATOM   1938 C C    . PRO A 1 141 ? 2.11100  21.05500 24.99500  1.000 15.90717 ? 145 PRO A C    1 
ATOM   1939 O O    . PRO A 1 141 ? 2.42700  21.51900 23.89300  1.000 14.86494 ? 145 PRO A O    1 
ATOM   1940 C CB   . PRO A 1 141 ? 2.24400  18.55900 25.45200  1.000 16.61778 ? 145 PRO A CB   1 
ATOM   1941 C CG   . PRO A 1 141 ? 2.66300  17.80200 26.69000  1.000 17.46788 ? 145 PRO A CG   1 
ATOM   1942 C CD   . PRO A 1 141 ? 2.85500  18.80100 27.76800  1.000 16.24405 ? 145 PRO A CD   1 
ATOM   1943 H HA   . PRO A 1 141 ? 3.78200  19.89100 25.11600  1.000 19.80000 ? 145 PRO A HA   1 
ATOM   1944 H HB2  . PRO A 1 141 ? 1.28100  18.67500 25.42300  1.000 19.95000 ? 145 PRO A HB2  1 
ATOM   1945 H HB3  . PRO A 1 141 ? 2.54800  18.11000 24.64800  1.000 19.95000 ? 145 PRO A HB3  1 
ATOM   1946 H HG2  . PRO A 1 141 ? 1.96700  17.17100 26.93300  1.000 20.97000 ? 145 PRO A HG2  1 
ATOM   1947 H HG3  . PRO A 1 141 ? 3.49200  17.33000 26.51400  1.000 20.97000 ? 145 PRO A HG3  1 
ATOM   1948 H HD2  . PRO A 1 141 ? 2.04200  18.90700 28.28700  1.000 19.50000 ? 145 PRO A HD2  1 
ATOM   1949 H HD3  . PRO A 1 141 ? 3.58800  18.54400 28.34800  1.000 19.50000 ? 145 PRO A HD3  1 
ATOM   1950 N N    . ALA A 1 142 ? 1.07300  21.52000 25.69000  1.000 15.18866 ? 146 ALA A N    1 
ATOM   1951 C CA   . ALA A 1 142 ? 0.29000  22.63200 25.17800  1.000 15.20445 ? 146 ALA A CA   1 
ATOM   1952 C C    . ALA A 1 142 ? 1.09700  23.92200 25.12000  1.000 15.34921 ? 146 ALA A C    1 
ATOM   1953 O O    . ALA A 1 142 ? 0.88200  24.74800 24.22900  1.000 15.86243 ? 146 ALA A O    1 
ATOM   1954 C CB   . ALA A 1 142 ? -0.98000 22.81900 26.00800  1.000 16.04929 ? 146 ALA A CB   1 
ATOM   1955 H H    . ALA A 1 142 ? 0.80700  21.21200 26.44700  1.000 18.23000 ? 146 ALA A H    1 
ATOM   1956 H HA   . ALA A 1 142 ? 0.02100  22.41700 24.27100  1.000 18.25000 ? 146 ALA A HA   1 
ATOM   1957 H HB1  . ALA A 1 142 ? -1.48900 23.56000 25.64500  1.000 19.27000 ? 146 ALA A HB1  1 
ATOM   1958 H HB2  . ALA A 1 142 ? -1.50700 22.00500 25.96800  1.000 19.27000 ? 146 ALA A HB2  1 
ATOM   1959 H HB3  . ALA A 1 142 ? -0.73200 23.00700 26.92700  1.000 19.27000 ? 146 ALA A HB3  1 
ATOM   1960 N N    . GLY A 1 143 ? 1.99600  24.14400 26.08100  1.000 14.61491 ? 147 GLY A N    1 
ATOM   1961 C CA   . GLY A 1 143 ? 2.80400  25.34900 26.03300  1.000 14.75177 ? 147 GLY A CA   1 
ATOM   1962 C C    . GLY A 1 143 ? 3.76500  25.36100 24.85700  1.000 14.74387 ? 147 GLY A C    1 
ATOM   1963 O O    . GLY A 1 143 ? 3.96900  26.39700 24.21900  1.000 15.93349 ? 147 GLY A O    1 
ATOM   1964 H H    . GLY A 1 143 ? 2.15000  23.62500 26.74900  1.000 17.54000 ? 147 GLY A H    1 
ATOM   1965 H HA2  . GLY A 1 143 ? 2.22200  26.12100 25.96000  1.000 17.71000 ? 147 GLY A HA2  1 
ATOM   1966 H HA3  . GLY A 1 143 ? 3.32100  25.41900 26.85100  1.000 17.71000 ? 147 GLY A HA3  1 
ATOM   1967 N N    . LEU A 1 144 ? 4.37600  24.22100 24.55200  1.000 13.95694 ? 148 LEU A N    1 
ATOM   1968 C CA   . LEU A 1 144 ? 5.22400  24.18000 23.36200  1.000 13.65164 ? 148 LEU A CA   1 
ATOM   1969 C C    . LEU A 1 144 ? 4.39200  24.34500 22.10000  1.000 13.95167 ? 148 LEU A C    1 
ATOM   1970 O O    . LEU A 1 144 ? 4.79100  25.05700 21.17100  1.000 14.08064 ? 148 LEU A O    1 
ATOM   1971 C CB   . LEU A 1 144 ? 6.01100  22.87100 23.30600  1.000 13.97536 ? 148 LEU A CB   1 
ATOM   1972 C CG   . LEU A 1 144 ? 6.96400  22.75700 22.09700  1.000 13.91483 ? 148 LEU A CG   1 
ATOM   1973 C CD1  . LEU A 1 144 ? 7.87400  23.95500 22.01600  1.000 15.52818 ? 148 LEU A CD1  1 
ATOM   1974 C CD2  . LEU A 1 144 ? 7.75000  21.48100 22.18000  1.000 15.20445 ? 148 LEU A CD2  1 
ATOM   1975 H H    . LEU A 1 144 ? 4.32100  23.48700 24.99700  1.000 16.76000 ? 148 LEU A H    1 
ATOM   1976 H HA   . LEU A 1 144 ? 5.86300  24.90800 23.41300  1.000 16.39000 ? 148 LEU A HA   1 
ATOM   1977 H HB2  . LEU A 1 144 ? 6.54700  22.79800 24.11200  1.000 16.78000 ? 148 LEU A HB2  1 
ATOM   1978 H HB3  . LEU A 1 144 ? 5.38300  22.13400 23.25700  1.000 16.78000 ? 148 LEU A HB3  1 
ATOM   1979 H HG   . LEU A 1 144 ? 6.44300  22.73600 21.27900  1.000 16.70000 ? 148 LEU A HG   1 
ATOM   1980 H HD11 . LEU A 1 144 ? 8.64000  23.73200 21.46400  1.000 18.64000 ? 148 LEU A HD11 1 
ATOM   1981 H HD12 . LEU A 1 144 ? 7.38700  24.69500 21.62200  1.000 18.64000 ? 148 LEU A HD12 1 
ATOM   1982 H HD13 . LEU A 1 144 ? 8.16800  24.18900 22.91000  1.000 18.64000 ? 148 LEU A HD13 1 
ATOM   1983 H HD21 . LEU A 1 144 ? 8.32900  21.41600 21.40500  1.000 18.25000 ? 148 LEU A HD21 1 
ATOM   1984 H HD22 . LEU A 1 144 ? 8.28300  21.49100 22.99100  1.000 18.25000 ? 148 LEU A HD22 1 
ATOM   1985 H HD23 . LEU A 1 144 ? 7.13500  20.73200 22.19800  1.000 18.25000 ? 148 LEU A HD23 1 
ATOM   1986 N N    . THR A 1 145 ? 3.24100  23.67800 22.03900  1.000 13.02788 ? 149 THR A N    1 
ATOM   1987 C CA   . THR A 1 145 ? 2.34000  23.87100 20.89500  1.000 12.51203 ? 149 THR A CA   1 
ATOM   1988 C C    . THR A 1 145 ? 1.99000  25.34600 20.72800  1.000 13.88061 ? 149 THR A C    1 
ATOM   1989 O O    . THR A 1 145 ? 2.02900  25.89400 19.61000  1.000 13.92535 ? 149 THR A O    1 
ATOM   1990 C CB   . THR A 1 145 ? 1.09800  22.98800 21.05200  1.000 12.89891 ? 149 THR A CB   1 
ATOM   1991 O OG1  . THR A 1 145 ? 1.50900  21.62000 21.10600  1.000 13.05420 ? 149 THR A OG1  1 
ATOM   1992 C CG2  . THR A 1 145 ? 0.14300  23.17200 19.87300  1.000 13.32791 ? 149 THR A CG2  1 
ATOM   1993 H H    . THR A 1 145 ? 2.96100  23.12000 22.63000  1.000 15.64000 ? 149 THR A H    1 
ATOM   1994 H HA   . THR A 1 145 ? 2.77700  23.58800 20.07700  1.000 15.02000 ? 149 THR A HA   1 
ATOM   1995 H HB   . THR A 1 145 ? 0.62600  23.23200 21.86400  1.000 15.49000 ? 149 THR A HB   1 
ATOM   1996 H HG1  . THR A 1 145 ? 1.96500  21.48400 21.79800  1.000 15.67000 ? 149 THR A HG1  1 
ATOM   1997 H HG21 . THR A 1 145 ? -0.58100 22.52900 19.92800  1.000 16.00000 ? 149 THR A HG21 1 
ATOM   1998 H HG22 . THR A 1 145 ? -0.23000 24.06800 19.88600  1.000 16.00000 ? 149 THR A HG22 1 
ATOM   1999 H HG23 . THR A 1 145 ? 0.61800  23.04100 19.03800  1.000 16.00000 ? 149 THR A HG23 1 
ATOM   2000 N N    . ALA A 1 146 ? 1.68100  26.02200 21.83600  1.000 14.32014 ? 150 ALA A N    1 
ATOM   2001 C CA   . ALA A 1 146 ? 1.37800  27.44600 21.77800  1.000 15.18077 ? 150 ALA A CA   1 
ATOM   2002 C C    . ALA A 1 146 ? 2.54100  28.23100 21.20000  1.000 14.94390 ? 150 ALA A C    1 
ATOM   2003 O O    . ALA A 1 146 ? 2.33700  29.17200 20.43000  1.000 14.77546 ? 150 ALA A O    1 
ATOM   2004 C CB   . ALA A 1 146 ? 1.02400  27.98000 23.17000  1.000 16.34143 ? 150 ALA A CB   1 
ATOM   2005 H H    . ALA A 1 146 ? 1.64000  25.68200 22.62500  1.000 17.19000 ? 150 ALA A H    1 
ATOM   2006 H HA   . ALA A 1 146 ? 0.60500  27.56800 21.20500  1.000 18.22000 ? 150 ALA A HA   1 
ATOM   2007 H HB1  . ALA A 1 146 ? 0.79200  28.91900 23.09800  1.000 19.62000 ? 150 ALA A HB1  1 
ATOM   2008 H HB2  . ALA A 1 146 ? 0.27000  27.47900 23.51900  1.000 19.62000 ? 150 ALA A HB2  1 
ATOM   2009 H HB3  . ALA A 1 146 ? 1.79100  27.87300 23.75400  1.000 19.62000 ? 150 ALA A HB3  1 
ATOM   2010 N N    . PHE A 1 147 ? 3.76800  27.89000 21.58600  1.000 14.49121 ? 151 PHE A N    1 
ATOM   2011 C CA   . PHE A 1 147 ? 4.89800  28.60800 21.01100  1.000 14.57280 ? 151 PHE A CA   1 
ATOM   2012 C C    . PHE A 1 147 ? 4.94300  28.43200 19.49400  1.000 14.47542 ? 151 PHE A C    1 
ATOM   2013 O O    . PHE A 1 147 ? 5.16500  29.39300 18.74100  1.000 15.27552 ? 151 PHE A O    1 
ATOM   2014 C CB   . PHE A 1 147 ? 6.21600  28.15600 21.62000  1.000 15.49923 ? 151 PHE A CB   1 
ATOM   2015 C CG   . PHE A 1 147 ? 7.40100  28.72500 20.90500  1.000 15.37553 ? 151 PHE A CG   1 
ATOM   2016 C CD1  . PHE A 1 147 ? 7.69000  30.06900 21.01300  1.000 15.77558 ? 151 PHE A CD1  1 
ATOM   2017 C CD2  . PHE A 1 147 ? 8.17700  27.94000 20.07600  1.000 16.60462 ? 151 PHE A CD2  1 
ATOM   2018 C CE1  . PHE A 1 147 ? 8.75700  30.62400 20.34700  1.000 16.01508 ? 151 PHE A CE1  1 
ATOM   2019 C CE2  . PHE A 1 147 ? 9.25800  28.48900 19.39900  1.000 16.40723 ? 151 PHE A CE2  1 
ATOM   2020 C CZ   . PHE A 1 147 ? 9.54000  29.83700 19.53400  1.000 15.95981 ? 151 PHE A CZ   1 
ATOM   2021 H H    . PHE A 1 147 ? 3.96400  27.27500 22.15300  1.000 17.40000 ? 151 PHE A H    1 
ATOM   2022 H HA   . PHE A 1 147 ? 4.78800  29.54900 21.22100  1.000 17.50000 ? 151 PHE A HA   1 
ATOM   2023 H HB2  . PHE A 1 147 ? 6.25400  28.44600 22.54500  1.000 18.61000 ? 151 PHE A HB2  1 
ATOM   2024 H HB3  . PHE A 1 147 ? 6.27100  27.18900 21.57400  1.000 18.61000 ? 151 PHE A HB3  1 
ATOM   2025 H HD1  . PHE A 1 147 ? 7.15300  30.60900 21.54600  1.000 18.94000 ? 151 PHE A HD1  1 
ATOM   2026 H HD2  . PHE A 1 147 ? 7.97500  27.03900 19.96900  1.000 19.93000 ? 151 PHE A HD2  1 
ATOM   2027 H HE1  . PHE A 1 147 ? 8.94900  31.52900 20.44600  1.000 19.23000 ? 151 PHE A HE1  1 
ATOM   2028 H HE2  . PHE A 1 147 ? 9.79100  27.95300 18.85800  1.000 19.70000 ? 151 PHE A HE2  1 
ATOM   2029 H HZ   . PHE A 1 147 ? 10.25700 30.21100 19.07500  1.000 19.16000 ? 151 PHE A HZ   1 
ATOM   2030 N N    . MET A 1 148 ? 4.74000  27.20300 19.03200  1.000 12.96208 ? 152 MET A N    1 
ATOM   2031 C CA   . MET A 1 148 ? 4.74100  26.94800 17.59300  1.000 13.43845 ? 152 MET A CA   1 
ATOM   2032 C C    . MET A 1 148 ? 3.61600  27.70700 16.90100  1.000 13.68848 ? 152 MET A C    1 
ATOM   2033 O O    . MET A 1 148 ? 3.82200  28.27700 15.83300  1.000 14.19907 ? 152 MET A O    1 
ATOM   2034 C CB   . MET A 1 148 ? 4.69300  25.44500 17.34200  1.000 13.72796 ? 152 MET A CB   1 
ATOM   2035 C CG   . MET A 1 148 ? 5.92300  24.74000 17.90300  1.000 13.28844 ? 152 MET A CG   1 
ATOM   2036 S SD   . MET A 1 148 ? 7.48600  25.28200 17.19000  1.000 13.30423 ? 152 MET A SD   1 
ATOM   2037 C CE   . MET A 1 148 ? 7.40400  24.38100 15.61700  1.000 14.32014 ? 152 MET A CE   1 
ATOM   2038 H H    . MET A 1 148 ? 4.60100  26.50800 19.52000  1.000 15.56000 ? 152 MET A H    1 
ATOM   2039 H HA   . MET A 1 148 ? 5.57200  27.26200 17.20200  1.000 16.13000 ? 152 MET A HA   1 
ATOM   2040 H HB2  . MET A 1 148 ? 3.90600  25.07400 17.77200  1.000 16.48000 ? 152 MET A HB2  1 
ATOM   2041 H HB3  . MET A 1 148 ? 4.65700  25.28200 16.38600  1.000 16.48000 ? 152 MET A HB3  1 
ATOM   2042 H HG2  . MET A 1 148 ? 5.96500  24.90500 18.85800  1.000 15.95000 ? 152 MET A HG2  1 
ATOM   2043 H HG3  . MET A 1 148 ? 5.83900  23.78900 17.73300  1.000 15.95000 ? 152 MET A HG3  1 
ATOM   2044 H HE1  . MET A 1 148 ? 8.21200  24.55600 15.11100  1.000 17.19000 ? 152 MET A HE1  1 
ATOM   2045 H HE2  . MET A 1 148 ? 7.32700  23.43200 15.80100  1.000 17.19000 ? 152 MET A HE2  1 
ATOM   2046 H HE3  . MET A 1 148 ? 6.62900  24.68500 15.11900  1.000 17.19000 ? 152 MET A HE3  1 
ATOM   2047 N N    . ARG A 1 149 ? 2.43400  27.76400 17.50600  1.000 13.94115 ? 153 ARG A N    1 
ATOM   2048 C CA   . ARG A 1 149 ? 1.37300  28.59500 16.94300  1.000 13.58847 ? 153 ARG A CA   1 
ATOM   2049 C C    . ARG A 1 149 ? 1.81700  30.05500 16.82200  1.000 14.46226 ? 153 ARG A C    1 
ATOM   2050 O O    . ARG A 1 149 ? 1.45500  30.74400 15.86500  1.000 15.00180 ? 153 ARG A O    1 
ATOM   2051 C CB   . ARG A 1 149 ? 0.10700  28.49700 17.80100  1.000 13.87272 ? 153 ARG A CB   1 
ATOM   2052 C CG   . ARG A 1 149 ? -0.56300 27.13600 17.80100  1.000 14.58596 ? 153 ARG A CG   1 
ATOM   2053 C CD   . ARG A 1 149 ? -1.20800 26.78100 16.43800  1.000 14.44910 ? 153 ARG A CD   1 
ATOM   2054 N NE   . ARG A 1 149 ? -1.72600 25.42400 16.52500  1.000 13.98062 ? 153 ARG A NE   1 
ATOM   2055 C CZ   . ARG A 1 149 ? -1.00600 24.31600 16.42100  1.000 13.54110 ? 153 ARG A CZ   1 
ATOM   2056 N NH1  . ARG A 1 149 ? 0.20600  24.31600 15.87700  1.000 13.27528 ? 153 ARG A NH1  1 
ATOM   2057 N NH2  . ARG A 1 149 ? -1.49900 23.17900 16.89300  1.000 13.56215 ? 153 ARG A NH2  1 
ATOM   2058 H H    . ARG A 1 149 ? 2.22400  27.34200 18.22600  1.000 16.74000 ? 153 ARG A H    1 
ATOM   2059 H HA   . ARG A 1 149 ? 1.16300  28.26400 16.05500  1.000 16.31000 ? 153 ARG A HA   1 
ATOM   2060 H HB2  . ARG A 1 149 ? 0.34100  28.70600 18.71900  1.000 16.66000 ? 153 ARG A HB2  1 
ATOM   2061 H HB3  . ARG A 1 149 ? -0.54000 29.13900 17.46900  1.000 16.66000 ? 153 ARG A HB3  1 
ATOM   2062 H HG2  . ARG A 1 149 ? 0.10000  26.45800 18.00400  1.000 17.51000 ? 153 ARG A HG2  1 
ATOM   2063 H HG3  . ARG A 1 149 ? -1.26200 27.12800 18.47400  1.000 17.51000 ? 153 ARG A HG3  1 
ATOM   2064 H HD2  . ARG A 1 149 ? -1.93800 27.39000 16.24500  1.000 17.35000 ? 153 ARG A HD2  1 
ATOM   2065 H HD3  . ARG A 1 149 ? -0.54400 26.82500 15.73200  1.000 17.35000 ? 153 ARG A HD3  1 
ATOM   2066 H HE   . ARG A 1 149 ? -2.57200 25.33300 16.65400  1.000 16.78000 ? 153 ARG A HE   1 
ATOM   2067 H HH11 . ARG A 1 149 ? 0.54300  25.04900 15.58000  1.000 15.94000 ? 153 ARG A HH11 1 
ATOM   2068 H HH12 . ARG A 1 149 ? 0.65200  23.58300 15.82200  1.000 15.94000 ? 153 ARG A HH12 1 
ATOM   2069 H HH21 . ARG A 1 149 ? -2.27700 23.16700 17.26000  1.000 16.28000 ? 153 ARG A HH21 1 
ATOM   2070 H HH22 . ARG A 1 149 ? -1.04100 22.45300 16.83200  1.000 16.28000 ? 153 ARG A HH22 1 
ATOM   2071 N N    . SER A 1 150 ? 2.57500  30.55800 17.81100  1.000 14.03326 ? 154 SER A N    1 
ATOM   2072 C CA   . SER A 1 150 ? 2.92800  31.97000 17.85500  1.000 15.57818 ? 154 SER A CA   1 
ATOM   2073 C C    . SER A 1 150 ? 3.86300  32.35500 16.71900  1.000 16.20984 ? 154 SER A C    1 
ATOM   2074 O O    . SER A 1 150 ? 3.95100  33.54500 16.39000  1.000 18.01005 ? 154 SER A O    1 
ATOM   2075 C CB   . SER A 1 150 ? 3.51700  32.33400 19.22800  1.000 17.82845 ? 154 SER A CB   1 
ATOM   2076 O OG   . SER A 1 150 ? 4.89600  31.99800 19.31500  1.000 17.75476 ? 154 SER A OG   1 
ATOM   2077 H H    . SER A 1 150 ? 2.89300  30.09700 18.46400  1.000 16.85000 ? 154 SER A H    1 
ATOM   2078 H HA   . SER A 1 150 ? 2.12600  32.50700 17.75700  1.000 18.70000 ? 154 SER A HA   1 
ATOM   2079 H HB2  . SER A 1 150 ? 3.41900  33.28900 19.36700  1.000 21.40000 ? 154 SER A HB2  1 
ATOM   2080 H HB3  . SER A 1 150 ? 3.03300  31.84800 19.91400  1.000 21.40000 ? 154 SER A HB3  1 
ATOM   2081 H HG   . SER A 1 150 ? 4.99800  31.17200 19.20100  1.000 21.31000 ? 154 SER A HG   1 
ATOM   2082 N N    . ILE A 1 151 ? 4.56000  31.38500 16.12500  1.000 15.68346 ? 155 ILE A N    1 
ATOM   2083 C CA   . ILE A 1 151 ? 5.41100  31.66800 14.97400  1.000 15.55713 ? 155 ILE A CA   1 
ATOM   2084 C C    . ILE A 1 151 ? 4.72200  31.34600 13.65500  1.000 15.72820 ? 155 ILE A C    1 
ATOM   2085 O O    . ILE A 1 151 ? 5.35900  31.43800 12.59900  1.000 17.38893 ? 155 ILE A O    1 
ATOM   2086 C CB   . ILE A 1 151 ? 6.80700  30.99600 15.09600  1.000 15.55450 ? 155 ILE A CB   1 
ATOM   2087 C CG1  . ILE A 1 151 ? 6.73200  29.47400 14.95800  1.000 15.05970 ? 155 ILE A CG1  1 
ATOM   2088 C CG2  . ILE A 1 151 ? 7.47100  31.40500 16.41000  1.000 16.51514 ? 155 ILE A CG2  1 
ATOM   2089 C CD1  . ILE A 1 151 ? 8.08500  28.76800 14.80100  1.000 14.90705 ? 155 ILE A CD1  1 
ATOM   2090 H H    . ILE A 1 151 ? 4.55400  30.56100 16.37100  1.000 18.83000 ? 155 ILE A H    1 
ATOM   2091 H HA   . ILE A 1 151 ? 5.57700  32.62300 14.96300  1.000 18.68000 ? 155 ILE A HA   1 
ATOM   2092 H HB   . ILE A 1 151 ? 7.35100  31.31200 14.35700  1.000 18.67000 ? 155 ILE A HB   1 
ATOM   2093 H HG12 . ILE A 1 151 ? 6.30700  29.11500 15.75200  1.000 18.08000 ? 155 ILE A HG12 1 
ATOM   2094 H HG13 . ILE A 1 151 ? 6.20100  29.26300 14.17400  1.000 18.08000 ? 155 ILE A HG13 1 
ATOM   2095 H HG21 . ILE A 1 151 ? 8.38100  31.06900 16.42200  1.000 19.83000 ? 155 ILE A HG21 1 
ATOM   2096 H HG22 . ILE A 1 151 ? 7.47500  32.37300 16.47300  1.000 19.83000 ? 155 ILE A HG22 1 
ATOM   2097 H HG23 . ILE A 1 151 ? 6.96900  31.02800 17.14800  1.000 19.83000 ? 155 ILE A HG23 1 
ATOM   2098 H HD11 . ILE A 1 151 ? 7.93200  27.82400 14.64100  1.000 17.89000 ? 155 ILE A HD11 1 
ATOM   2099 H HD12 . ILE A 1 151 ? 8.56000  29.15800 14.05000  1.000 17.89000 ? 155 ILE A HD12 1 
ATOM   2100 H HD13 . ILE A 1 151 ? 8.59900  28.88700 15.61500  1.000 17.89000 ? 155 ILE A HD13 1 
ATOM   2101 N N    . GLY A 1 152 ? 3.44400  30.97100 13.69300  1.000 14.65702 ? 156 GLY A N    1 
ATOM   2102 C CA   . GLY A 1 152 ? 2.65900  30.70700 12.48600  1.000 15.42290 ? 156 GLY A CA   1 
ATOM   2103 C C    . GLY A 1 152 ? 2.57700  29.25900 12.04500  1.000 14.88863 ? 156 GLY A C    1 
ATOM   2104 O O    . GLY A 1 152 ? 2.09800  28.99000 10.93100  1.000 15.92823 ? 156 GLY A O    1 
ATOM   2105 H H    . GLY A 1 152 ? 2.99900  30.85900 14.42000  1.000 17.60000 ? 156 GLY A H    1 
ATOM   2106 H HA2  . GLY A 1 152 ? 1.75300  31.01700 12.63800  1.000 18.51000 ? 156 GLY A HA2  1 
ATOM   2107 H HA3  . GLY A 1 152 ? 3.04700  31.21200 11.75400  1.000 18.51000 ? 156 GLY A HA3  1 
ATOM   2108 N N    . ASP A 1 153 ? 2.99400  28.31500 12.88200  1.000 13.08315 ? 157 ASP A N    1 
ATOM   2109 C CA   . ASP A 1 153 ? 2.92500  26.89600 12.57000  1.000 13.55426 ? 157 ASP A CA   1 
ATOM   2110 C C    . ASP A 1 153 ? 1.60800  26.37100 13.11700  1.000 13.44109 ? 157 ASP A C    1 
ATOM   2111 O O    . ASP A 1 153 ? 1.40800  26.31200 14.33700  1.000 13.79376 ? 157 ASP A O    1 
ATOM   2112 C CB   . ASP A 1 153 ? 4.11200  26.18100 13.20700  1.000 13.19632 ? 157 ASP A CB   1 
ATOM   2113 C CG   . ASP A 1 153 ? 4.21400  24.71000 12.86000  1.000 12.99893 ? 157 ASP A CG   1 
ATOM   2114 O OD1  . ASP A 1 153 ? 3.16200  24.05400 12.58900  1.000 12.61730 ? 157 ASP A OD1  1 
ATOM   2115 O OD2  . ASP A 1 153 ? 5.36000  24.19000 12.88300  1.000 13.50162 ? 157 ASP A OD2  1 
ATOM   2116 H H    . ASP A 1 153 ? 3.32900  28.47800 13.65700  1.000 15.71000 ? 157 ASP A H    1 
ATOM   2117 H HA   . ASP A 1 153 ? 2.94700  26.74700 11.61100  1.000 16.27000 ? 157 ASP A HA   1 
ATOM   2118 H HB2  . ASP A 1 153 ? 4.92900  26.61000 12.90800  1.000 15.84000 ? 157 ASP A HB2  1 
ATOM   2119 H HB3  . ASP A 1 153 ? 4.03500  26.25000 14.17100  1.000 15.84000 ? 157 ASP A HB3  1 
ATOM   2120 N N    . THR A 1 154 ? 0.68100  26.06300 12.21300  1.000 14.12538 ? 158 THR A N    1 
ATOM   2121 C CA   . THR A 1 154 ? -0.62900 25.53700 12.57000  1.000 14.20170 ? 158 THR A CA   1 
ATOM   2122 C C    . THR A 1 154 ? -0.69400 24.01600 12.46600  1.000 13.14368 ? 158 THR A C    1 
ATOM   2123 O O    . THR A 1 154 ? -1.76600 23.43100 12.68200  1.000 14.33067 ? 158 THR A O    1 
ATOM   2124 C CB   . THR A 1 154 ? -1.69900 26.15500 11.66700  1.000 16.13615 ? 158 THR A CB   1 
ATOM   2125 O OG1  . THR A 1 154 ? -1.35100 25.92300 10.29200  1.000 17.85214 ? 158 THR A OG1  1 
ATOM   2126 C CG2  . THR A 1 154 ? -1.79200 27.65800 11.89200  1.000 17.98110 ? 158 THR A CG2  1 
ATOM   2127 H H    . THR A 1 154 ? 0.79300  26.15400 11.36500  1.000 16.96000 ? 158 THR A H    1 
ATOM   2128 H HA   . THR A 1 154 ? -0.82900 25.78400 13.48700  1.000 17.05000 ? 158 THR A HA   1 
ATOM   2129 H HB   . THR A 1 154 ? -2.55800 25.75500 11.87100  1.000 19.37000 ? 158 THR A HB   1 
ATOM   2130 H HG1  . THR A 1 154 ? -1.33900 25.09900 10.13300  1.000 21.43000 ? 158 THR A HG1  1 
ATOM   2131 H HG21 . THR A 1 154 ? -2.51100 28.02900 11.35800  1.000 21.58000 ? 158 THR A HG21 1 
ATOM   2132 H HG22 . THR A 1 154 ? -1.96800 27.84200 12.82800  1.000 21.58000 ? 158 THR A HG22 1 
ATOM   2133 H HG23 . THR A 1 154 ? -0.95800 28.08300 11.63800  1.000 21.58000 ? 158 THR A HG23 1 
ATOM   2134 N N    . THR A 1 155 ? 0.42400  23.35900 12.14300  1.000 12.73574 ? 159 THR A N    1 
ATOM   2135 C CA   . THR A 1 155 ? 0.45000  21.91200 11.95400  1.000 11.94880 ? 159 THR A CA   1 
ATOM   2136 C C    . THR A 1 155 ? 0.98400  21.18300 13.18100  1.000 12.03302 ? 159 THR A C    1 
ATOM   2137 O O    . THR A 1 155 ? 0.45000  20.14800 13.58400  1.000 12.30147 ? 159 THR A O    1 
ATOM   2138 C CB   . THR A 1 155 ? 1.34700  21.57400 10.74600  1.000 12.82259 ? 159 THR A CB   1 
ATOM   2139 O OG1  . THR A 1 155 ? 0.91800  22.34900 9.61500   1.000 13.83587 ? 159 THR A OG1  1 
ATOM   2140 C CG2  . THR A 1 155 ? 1.27600  20.09800 10.43500  1.000 13.71743 ? 159 THR A CG2  1 
ATOM   2141 H H    . THR A 1 155 ? 1.18800  23.73700 12.02600  1.000 15.29000 ? 159 THR A H    1 
ATOM   2142 H HA   . THR A 1 155 ? -0.45200 21.60000 11.77900  1.000 14.34000 ? 159 THR A HA   1 
ATOM   2143 H HB   . THR A 1 155 ? 2.27300  21.78700 10.94300  1.000 15.39000 ? 159 THR A HB   1 
ATOM   2144 H HG1  . THR A 1 155 ? 1.38500  22.15800 8.94300   1.000 16.61000 ? 159 THR A HG1  1 
ATOM   2145 H HG21 . THR A 1 155 ? 1.72700  19.91400 9.59600   1.000 16.47000 ? 159 THR A HG21 1 
ATOM   2146 H HG22 . THR A 1 155 ? 1.70400  19.58900 11.14100  1.000 16.47000 ? 159 THR A HG22 1 
ATOM   2147 H HG23 . THR A 1 155 ? 0.35000  19.81800 10.36200  1.000 16.47000 ? 159 THR A HG23 1 
ATOM   2148 N N    . PHE A 1 156 ? 2.07100  21.69000 13.74500  1.000 11.55138 ? 160 PHE A N    1 
ATOM   2149 C CA   . PHE A 1 156 ? 2.73500  21.06400 14.88200  1.000 11.84879 ? 160 PHE A CA   1 
ATOM   2150 C C    . PHE A 1 156 ? 1.75600  20.81400 16.01700  1.000 12.33043 ? 160 PHE A C    1 
ATOM   2151 O O    . PHE A 1 156 ? 0.98100  21.70200 16.40400  1.000 12.91734 ? 160 PHE A O    1 
ATOM   2152 C CB   . PHE A 1 156 ? 3.80900  22.03700 15.36400  1.000 12.08829 ? 160 PHE A CB   1 
ATOM   2153 C CG   . PHE A 1 156 ? 4.59200  21.56400 16.56600  1.000 12.24357 ? 160 PHE A CG   1 
ATOM   2154 C CD1  . PHE A 1 156 ? 4.06900  21.68200 17.85100  1.000 12.55940 ? 160 PHE A CD1  1 
ATOM   2155 C CD2  . PHE A 1 156 ? 5.87000  21.04500 16.42200  1.000 12.74363 ? 160 PHE A CD2  1 
ATOM   2156 C CE1  . PHE A 1 156 ? 4.79000  21.25700 18.94800  1.000 13.35423 ? 160 PHE A CE1  1 
ATOM   2157 C CE2  . PHE A 1 156 ? 6.59700  20.62600 17.51500  1.000 13.58584 ? 160 PHE A CE2  1 
ATOM   2158 C CZ   . PHE A 1 156 ? 6.04700  20.73000 18.78500  1.000 13.55426 ? 160 PHE A CZ   1 
ATOM   2159 H H    . PHE A 1 156 ? 2.45400  22.41300 13.48400  1.000 13.87000 ? 160 PHE A H    1 
ATOM   2160 H HA   . PHE A 1 156 ? 3.12000  20.21100 14.62500  1.000 14.23000 ? 160 PHE A HA   1 
ATOM   2161 H HB2  . PHE A 1 156 ? 4.44000  22.18300 14.64200  1.000 14.51000 ? 160 PHE A HB2  1 
ATOM   2162 H HB3  . PHE A 1 156 ? 3.38100  22.87400 15.60400  1.000 14.51000 ? 160 PHE A HB3  1 
ATOM   2163 H HD1  . PHE A 1 156 ? 3.22400  22.05200 17.97100  1.000 15.08000 ? 160 PHE A HD1  1 
ATOM   2164 H HD2  . PHE A 1 156 ? 6.24400  20.97900 15.57300  1.000 15.30000 ? 160 PHE A HD2  1 
ATOM   2165 H HE1  . PHE A 1 156 ? 4.42300  21.32800 19.79900  1.000 16.03000 ? 160 PHE A HE1  1 
ATOM   2166 H HE2  . PHE A 1 156 ? 7.45000  20.27400 17.40200  1.000 16.31000 ? 160 PHE A HE2  1 
ATOM   2167 H HZ   . PHE A 1 156 ? 6.53100  20.44400 19.52600  1.000 16.27000 ? 160 PHE A HZ   1 
ATOM   2168 N N    . ARG A 1 157 ? 1.84300  19.62500 16.60300  1.000 11.30136 ? 161 ARG A N    1 
ATOM   2169 C CA   . ARG A 1 157 ? 1.15100  19.40100 17.86400  1.000 12.59362 ? 161 ARG A CA   1 
ATOM   2170 C C    . ARG A 1 157 ? 1.98200  18.48700 18.73500  1.000 12.92787 ? 161 ARG A C    1 
ATOM   2171 O O    . ARG A 1 157 ? 2.39900  17.41800 18.30100  1.000 13.33844 ? 161 ARG A O    1 
ATOM   2172 C CB   . ARG A 1 157 ? -0.25400 18.83200 17.67900  1.000 13.55952 ? 161 ARG A CB   1 
ATOM   2173 C CG   . ARG A 1 157 ? -0.33500 17.59500 16.83400  1.000 12.72258 ? 161 ARG A CG   1 
ATOM   2174 C CD   . ARG A 1 157 ? -1.78900 17.13400 16.60900  1.000 13.77007 ? 161 ARG A CD   1 
ATOM   2175 N NE   . ARG A 1 157 ? -2.46200 16.74100 17.84200  1.000 14.14906 ? 161 ARG A NE   1 
ATOM   2176 C CZ   . ARG A 1 157 ? -3.69900 16.26000 17.88800  1.000 15.05707 ? 161 ARG A CZ   1 
ATOM   2177 N NH1  . ARG A 1 157 ? -4.42300 16.11500 16.78800  1.000 14.93337 ? 161 ARG A NH1  1 
ATOM   2178 N NH2  . ARG A 1 157 ? -4.22600 15.90500 19.06300  1.000 15.24920 ? 161 ARG A NH2  1 
ATOM   2179 H H    . ARG A 1 157 ? 2.28400  18.95300 16.29800  1.000 13.57000 ? 161 ARG A H    1 
ATOM   2180 H HA   . ARG A 1 157 ? 1.05500  20.25500 18.31400  1.000 15.12000 ? 161 ARG A HA   1 
ATOM   2181 H HB2  . ARG A 1 157 ? -0.61200 18.61000 18.55200  1.000 16.28000 ? 161 ARG A HB2  1 
ATOM   2182 H HB3  . ARG A 1 157 ? -0.80600 19.50800 17.25600  1.000 16.28000 ? 161 ARG A HB3  1 
ATOM   2183 H HG2  . ARG A 1 157 ? 0.06100  17.77500 15.96700  1.000 15.28000 ? 161 ARG A HG2  1 
ATOM   2184 H HG3  . ARG A 1 157 ? 0.14400  16.87700 17.27500  1.000 15.28000 ? 161 ARG A HG3  1 
ATOM   2185 H HD2  . ARG A 1 157 ? -2.29300 17.86300 16.21400  1.000 16.53000 ? 161 ARG A HD2  1 
ATOM   2186 H HD3  . ARG A 1 157 ? -1.78800 16.36900 16.01300  1.000 16.53000 ? 161 ARG A HD3  1 
ATOM   2187 H HE   . ARG A 1 157 ? -2.03300 16.82600 18.58200  1.000 16.98000 ? 161 ARG A HE   1 
ATOM   2188 H HH11 . ARG A 1 157 ? -4.09300 16.33300 16.02400  1.000 17.93000 ? 161 ARG A HH11 1 
ATOM   2189 H HH12 . ARG A 1 157 ? -5.22200 15.80100 16.83700  1.000 17.93000 ? 161 ARG A HH12 1 
ATOM   2190 H HH21 . ARG A 1 157 ? -3.76500 15.98800 19.78400  1.000 18.31000 ? 161 ARG A HH21 1 
ATOM   2191 H HH22 . ARG A 1 157 ? -5.02700 15.59300 19.09800  1.000 18.31000 ? 161 ARG A HH22 1 
ATOM   2192 N N    . LEU A 1 158 ? 2.21200  18.92000 19.96900  1.000 12.03829 ? 162 LEU A N    1 
ATOM   2193 C CA   . LEU A 1 158 ? 2.72000  18.04800 21.01500  1.000 12.89365 ? 162 LEU A CA   1 
ATOM   2194 C C    . LEU A 1 158 ? 1.58000  17.85200 22.00600  1.000 13.63321 ? 162 LEU A C    1 
ATOM   2195 O O    . LEU A 1 158 ? 0.90700  18.82000 22.39900  1.000 13.13315 ? 162 LEU A O    1 
ATOM   2196 C CB   . LEU A 1 158 ? 3.95700  18.61500 21.72400  1.000 12.95945 ? 162 LEU A CB   1 
ATOM   2197 C CG   . LEU A 1 158 ? 4.78700  17.48300 22.34300  1.000 14.10695 ? 162 LEU A CG   1 
ATOM   2198 C CD1  . LEU A 1 158 ? 5.55900  16.65500 21.30500  1.000 14.67018 ? 162 LEU A CD1  1 
ATOM   2199 C CD2  . LEU A 1 158 ? 5.76500  17.94700 23.40600  1.000 15.18340 ? 162 LEU A CD2  1 
ATOM   2200 H H    . LEU A 1 158 ? 2.07800  19.72900 20.22700  1.000 14.46000 ? 162 LEU A H    1 
ATOM   2201 H HA   . LEU A 1 158 ? 3.00000  17.20000 20.63500  1.000 15.48000 ? 162 LEU A HA   1 
ATOM   2202 H HB2  . LEU A 1 158 ? 4.50900  19.09000 21.08300  1.000 15.56000 ? 162 LEU A HB2  1 
ATOM   2203 H HB3  . LEU A 1 158 ? 3.67700  19.21700 22.43100  1.000 15.56000 ? 162 LEU A HB3  1 
ATOM   2204 H HG   . LEU A 1 158 ? 4.12300  16.91700 22.76600  1.000 16.93000 ? 162 LEU A HG   1 
ATOM   2205 H HD11 . LEU A 1 158 ? 6.12800  16.02000 21.76700  1.000 17.61000 ? 162 LEU A HD11 1 
ATOM   2206 H HD12 . LEU A 1 158 ? 4.92500  16.18300 20.74300  1.000 17.61000 ? 162 LEU A HD12 1 
ATOM   2207 H HD13 . LEU A 1 158 ? 6.10000  17.25100 20.76400  1.000 17.61000 ? 162 LEU A HD13 1 
ATOM   2208 H HD21 . LEU A 1 158 ? 6.24900  17.17900 23.74700  1.000 18.23000 ? 162 LEU A HD21 1 
ATOM   2209 H HD22 . LEU A 1 158 ? 6.38500  18.57900 23.01100  1.000 18.23000 ? 162 LEU A HD22 1 
ATOM   2210 H HD23 . LEU A 1 158 ? 5.27200  18.37400 24.12500  1.000 18.23000 ? 162 LEU A HD23 1 
ATOM   2211 N N    . ASP A 1 159 ? 1.35700  16.60400 22.38100  1.000 14.96232 ? 163 ASP A N    1 
ATOM   2212 C CA   . ASP A 1 159 ? 0.21000  16.19700 23.16600  1.000 14.47016 ? 163 ASP A CA   1 
ATOM   2213 C C    . ASP A 1 159 ? 0.58300  15.48100 24.45200  1.000 16.50198 ? 163 ASP A C    1 
ATOM   2214 O O    . ASP A 1 159 ? -0.16800 15.58000 25.44000  1.000 17.35471 ? 163 ASP A O    1 
ATOM   2215 C CB   . ASP A 1 159 ? -0.65900 15.25700 22.32000  1.000 14.49384 ? 163 ASP A CB   1 
ATOM   2216 C CG   . ASP A 1 159 ? -1.22000 15.94200 21.09400  1.000 13.96746 ? 163 ASP A CG   1 
ATOM   2217 O OD1  . ASP A 1 159 ? -0.53000 16.02800 20.05800  1.000 13.34897 ? 163 ASP A OD1  1 
ATOM   2218 O OD2  . ASP A 1 159 ? -2.36500 16.44000 21.19500  1.000 15.06233 ? 163 ASP A OD2  1 
ATOM   2219 H H    . ASP A 1 159 ? 1.87800  15.94900 22.18400  1.000 17.96000 ? 163 ASP A H    1 
ATOM   2220 H HA   . ASP A 1 159 ? -0.31400 16.97700 23.40900  1.000 17.37000 ? 163 ASP A HA   1 
ATOM   2221 H HB2  . ASP A 1 159 ? -0.12000 14.50600 22.02600  1.000 17.40000 ? 163 ASP A HB2  1 
ATOM   2222 H HB3  . ASP A 1 159 ? -1.40300 14.94200 22.85700  1.000 17.40000 ? 163 ASP A HB3  1 
ATOM   2223 N N    . ARG A 1 160 ? 1.71700  14.78400 24.48400  1.000 17.39156 ? 164 ARG A N    1 
ATOM   2224 C CA   . ARG A 1 160 ? 2.13700  13.96800 25.61900  1.000 19.66288 ? 164 ARG A CA   1 
ATOM   2225 C C    . ARG A 1 160 ? 3.57400  14.29200 26.03100  1.000 22.77642 ? 164 ARG A C    1 
ATOM   2226 O O    . ARG A 1 160 ? 4.25900  15.09200 25.40200  1.000 20.34191 ? 164 ARG A O    1 
ATOM   2227 C CB   . ARG A 1 160 ? 1.98900  12.48400 25.26900  1.000 20.73143 ? 164 ARG A CB   1 
ATOM   2228 C CG   . ARG A 1 160 ? 0.52500  12.05700 25.12600  1.000 20.51299 ? 164 ARG A CG   1 
ATOM   2229 C CD   . ARG A 1 160 ? 0.38900  10.67600 24.54900  1.000 20.17874 ? 164 ARG A CD   1 
ATOM   2230 N NE   . ARG A 1 160 ? 0.84600  10.68600 23.16100  1.000 19.26284 ? 164 ARG A NE   1 
ATOM   2231 C CZ   . ARG A 1 160 ? 1.04400  9.60800  22.42700  1.000 19.40759 ? 164 ARG A CZ   1 
ATOM   2232 N NH1  . ARG A 1 160 ? 0.78700  8.39500  22.88800  1.000 20.89461 ? 164 ARG A NH1  1 
ATOM   2233 N NH2  . ARG A 1 160 ? 1.53900  9.75100  21.20900  1.000 17.27049 ? 164 ARG A NH2  1 
ATOM   2234 H H    . ARG A 1 160 ? 2.28100  14.76900 23.83400  1.000 20.88000 ? 164 ARG A H    1 
ATOM   2235 H HA   . ARG A 1 160 ? 1.58100  14.18500 26.38300  1.000 23.60000 ? 164 ARG A HA   1 
ATOM   2236 H HB2  . ARG A 1 160 ? 2.43700  12.31100 24.42700  1.000 24.89000 ? 164 ARG A HB2  1 
ATOM   2237 H HB3  . ARG A 1 160 ? 2.39000  11.95100 25.97400  1.000 24.89000 ? 164 ARG A HB3  1 
ATOM   2238 H HG2  . ARG A 1 160 ? 0.10500  12.06200 26.00000  1.000 24.62000 ? 164 ARG A HG2  1 
ATOM   2239 H HG3  . ARG A 1 160 ? 0.06900  12.67700 24.53500  1.000 24.62000 ? 164 ARG A HG3  1 
ATOM   2240 H HD2  . ARG A 1 160 ? 0.93400  10.05200 25.05500  1.000 24.22000 ? 164 ARG A HD2  1 
ATOM   2241 H HD3  . ARG A 1 160 ? -0.54000 10.39900 24.57200  1.000 24.22000 ? 164 ARG A HD3  1 
ATOM   2242 H HE   . ARG A 1 160 ? 0.99700  11.45000 22.79700  1.000 23.12000 ? 164 ARG A HE   1 
ATOM   2243 H HH11 . ARG A 1 160 ? 0.48300  8.29400  23.68600  1.000 25.08000 ? 164 ARG A HH11 1 
ATOM   2244 H HH12 . ARG A 1 160 ? 0.92400  7.70800  22.38900  1.000 25.08000 ? 164 ARG A HH12 1 
ATOM   2245 H HH21 . ARG A 1 160 ? 1.72600  10.53500 20.91100  1.000 20.73000 ? 164 ARG A HH21 1 
ATOM   2246 H HH22 . ARG A 1 160 ? 1.67500  9.05900  20.71600  1.000 20.73000 ? 164 ARG A HH22 1 
ATOM   2247 N N    A TRP A 1 161 ? 3.99500  13.66800 27.12800  0.000 24.56347 ? 165 TRP A N    1 
ATOM   2248 N N    B TRP A 1 161 ? 3.92600  13.75300 27.19400  0.290 25.36883 ? 165 TRP A N    1 
ATOM   2249 N N    C TRP A 1 161 ? 4.08900  13.58400 27.04200  0.710 25.01353 ? 165 TRP A N    1 
ATOM   2250 C CA   A TRP A 1 161 ? 5.33900  13.78600 27.67200  0.000 26.13471 ? 165 TRP A CA   1 
ATOM   2251 C CA   B TRP A 1 161 ? 5.25800  13.79800 27.76100  0.290 27.50330 ? 165 TRP A CA   1 
ATOM   2252 C CA   C TRP A 1 161 ? 5.42600  13.80100 27.60200  0.710 25.06090 ? 165 TRP A CA   1 
ATOM   2253 C C    A TRP A 1 161 ? 6.17700  12.59400 27.21800  0.000 27.36907 ? 165 TRP A C    1 
ATOM   2254 C C    B TRP A 1 161 ? 6.00200  12.53200 27.35800  0.290 28.99032 ? 165 TRP A C    1 
ATOM   2255 C C    C TRP A 1 161 ? 6.40400  12.71000 27.14800  0.710 25.62676 ? 165 TRP A C    1 
ATOM   2256 O O    A TRP A 1 161 ? 5.68400  11.66400 26.57800  0.000 27.80597 ? 165 TRP A O    1 
ATOM   2257 O O    B TRP A 1 161 ? 5.42400  11.58800 26.81500  0.290 29.40616 ? 165 TRP A O    1 
ATOM   2258 O O    C TRP A 1 161 ? 6.01300  11.68700 26.58100  0.710 26.09523 ? 165 TRP A O    1 
ATOM   2259 C CB   A TRP A 1 161 ? 5.27300  13.84000 29.20700  0.000 26.37421 ? 165 TRP A CB   1 
ATOM   2260 C CB   B TRP A 1 161 ? 5.16800  13.86300 29.29000  0.290 28.20075 ? 165 TRP A CB   1 
ATOM   2261 C CB   C TRP A 1 161 ? 5.34600  13.85000 29.14700  0.710 25.12670 ? 165 TRP A CB   1 
ATOM   2262 C CG   A TRP A 1 161 ? 4.44900  14.99000 29.73700  0.000 26.67951 ? 165 TRP A CG   1 
ATOM   2263 C CG   B TRP A 1 161 ? 4.33900  15.00400 29.81000  0.290 28.99032 ? 165 TRP A CG   1 
ATOM   2264 C CG   C TRP A 1 161 ? 4.50400  15.00300 29.67900  0.710 26.06102 ? 165 TRP A CG   1 
ATOM   2265 C CD1  A TRP A 1 161 ? 3.08700  15.09000 29.74600  0.000 26.80848 ? 165 TRP A CD1  1 
ATOM   2266 C CD1  B TRP A 1 161 ? 2.97700  15.07400 29.86000  0.290 29.29299 ? 165 TRP A CD1  1 
ATOM   2267 C CD1  C TRP A 1 161 ? 3.14100  15.08900 29.69000  0.710 26.60845 ? 165 TRP A CD1  1 
ATOM   2268 C CD2  A TRP A 1 161 ? 4.94300  16.19500 30.33400  0.000 26.73478 ? 165 TRP A CD2  1 
ATOM   2269 C CD2  B TRP A 1 161 ? 4.82500  16.23400 30.36000  0.290 29.29562 ? 165 TRP A CD2  1 
ATOM   2270 C CD2  C TRP A 1 161 ? 4.98500  16.22100 30.26500  0.710 25.78467 ? 165 TRP A CD2  1 
ATOM   2271 N NE1  A TRP A 1 161 ? 2.70400  16.28700 30.30600  0.000 26.90323 ? 165 TRP A NE1  1 
ATOM   2272 N NE1  B TRP A 1 161 ? 2.58500  16.27600 30.40200  0.290 29.51933 ? 165 TRP A NE1  1 
ATOM   2273 N NE1  C TRP A 1 161 ? 2.74600  16.29000 30.23700  0.710 27.00061 ? 165 TRP A NE1  1 
ATOM   2274 C CE2  A TRP A 1 161 ? 3.82400  16.98200 30.67800  0.000 26.87164 ? 165 TRP A CE2  1 
ATOM   2275 C CE2  B TRP A 1 161 ? 3.70100  17.00500 30.71800  0.290 29.52986 ? 165 TRP A CE2  1 
ATOM   2276 C CE2  C TRP A 1 161 ? 3.85800  16.99800 30.60500  0.710 26.61898 ? 165 TRP A CE2  1 
ATOM   2277 C CE3  A TRP A 1 161 ? 6.22300  16.68600 30.61200  0.000 26.78742 ? 165 TRP A CE3  1 
ATOM   2278 C CE3  B TRP A 1 161 ? 6.10200  16.75700 30.58600  0.290 29.52986 ? 165 TRP A CE3  1 
ATOM   2279 C CE3  C TRP A 1 161 ? 6.25900  16.72300 30.54800  0.710 26.21630 ? 165 TRP A CE3  1 
ATOM   2280 C CZ2  A TRP A 1 161 ? 3.94700  18.23200 31.28200  0.000 26.84006 ? 165 TRP A CZ2  1 
ATOM   2281 C CZ2  B TRP A 1 161 ? 3.81500  18.27200 31.28500  0.290 29.54302 ? 165 TRP A CZ2  1 
ATOM   2282 C CZ2  C TRP A 1 161 ? 3.96600  18.25600 31.19900  0.710 26.39527 ? 165 TRP A CZ2  1 
ATOM   2283 C CZ3  A TRP A 1 161 ? 6.34200  17.92800 31.21300  0.000 26.82690 ? 165 TRP A CZ3  1 
ATOM   2284 C CZ3  B TRP A 1 161 ? 6.21300  18.01600 31.14700  0.290 29.66408 ? 165 TRP A CZ3  1 
ATOM   2285 C CZ3  C TRP A 1 161 ? 6.36500  17.97200 31.13500  0.710 26.73742 ? 165 TRP A CZ3  1 
ATOM   2286 C CH2  A TRP A 1 161 ? 5.21000  18.68600 31.54000  0.000 26.89007 ? 165 TRP A CH2  1 
ATOM   2287 C CH2  B TRP A 1 161 ? 5.07600  18.76000 31.48900  0.290 29.68251 ? 165 TRP A CH2  1 
ATOM   2288 C CH2  C TRP A 1 161 ? 5.22200  18.72900 31.44600  0.710 27.06377 ? 165 TRP A CH2  1 
ATOM   2289 H H    A TRP A 1 161 ? 3.49400  13.14700 27.59500  0.000 29.48000 ? 165 TRP A H    1 
ATOM   2290 H H    B TRP A 1 161 ? 3.37400  13.33000 27.70000  0.290 30.45000 ? 165 TRP A H    1 
ATOM   2291 H H    C TRP A 1 161 ? 3.66500  12.94800 27.43500  0.710 30.02000 ? 165 TRP A H    1 
ATOM   2292 H HA   A TRP A 1 161 ? 5.76000  14.60000 27.35400  0.000 31.37000 ? 165 TRP A HA   1 
ATOM   2293 H HA   B TRP A 1 161 ? 5.73300  14.58100 27.44100  0.290 33.01000 ? 165 TRP A HA   1 
ATOM   2294 H HA   C TRP A 1 161 ? 5.77300  14.64600 27.27600  0.710 30.08000 ? 165 TRP A HA   1 
ATOM   2295 H HB2  A TRP A 1 161 ? 4.87600  13.01700 29.53100  0.000 31.66000 ? 165 TRP A HB2  1 
ATOM   2296 H HB2  B TRP A 1 161 ? 4.77000  13.04000 29.61300  0.290 33.85000 ? 165 TRP A HB2  1 
ATOM   2297 H HB2  C TRP A 1 161 ? 4.95200  13.02300 29.46600  0.710 30.16000 ? 165 TRP A HB2  1 
ATOM   2298 H HB3  A TRP A 1 161 ? 6.17300  13.93400 29.55500  0.000 31.66000 ? 165 TRP A HB3  1 
ATOM   2299 H HB3  B TRP A 1 161 ? 6.06300  13.96200 29.65000  0.290 33.85000 ? 165 TRP A HB3  1 
ATOM   2300 H HB3  C TRP A 1 161 ? 6.24300  13.94900 29.50300  0.710 30.16000 ? 165 TRP A HB3  1 
ATOM   2301 H HD1  A TRP A 1 161 ? 2.50300  14.44400 29.42100  0.000 32.18000 ? 165 TRP A HD1  1 
ATOM   2302 H HD1  B TRP A 1 161 ? 2.39800  14.40600 29.57100  0.290 35.16000 ? 165 TRP A HD1  1 
ATOM   2303 H HD1  C TRP A 1 161 ? 2.56300  14.43200 29.37500  0.710 31.94000 ? 165 TRP A HD1  1 
ATOM   2304 H HE1  A TRP A 1 161 ? 1.89300  16.55500 30.40700  0.000 32.29000 ? 165 TRP A HE1  1 
ATOM   2305 H HE1  B TRP A 1 161 ? 1.77200  16.52900 30.52200  0.290 35.43000 ? 165 TRP A HE1  1 
ATOM   2306 H HE1  C TRP A 1 161 ? 1.93300  16.55300 30.33200  0.710 32.41000 ? 165 TRP A HE1  1 
ATOM   2307 H HE3  A TRP A 1 161 ? 6.97800  16.18800 30.39800  0.000 32.15000 ? 165 TRP A HE3  1 
ATOM   2308 H HE3  B TRP A 1 161 ? 6.86100  16.26900 30.36300  0.290 35.45000 ? 165 TRP A HE3  1 
ATOM   2309 H HE3  C TRP A 1 161 ? 7.02000  16.22700 30.34700  0.710 31.47000 ? 165 TRP A HE3  1 
ATOM   2310 H HZ2  A TRP A 1 161 ? 3.19800  18.73700 31.50100  0.000 32.21000 ? 165 TRP A HZ2  1 
ATOM   2311 H HZ2  B TRP A 1 161 ? 3.06200  18.76700 31.51600  0.290 35.46000 ? 165 TRP A HZ2  1 
ATOM   2312 H HZ2  C TRP A 1 161 ? 3.21100  18.75300 31.41700  0.710 31.68000 ? 165 TRP A HZ2  1 
ATOM   2313 H HZ3  A TRP A 1 161 ? 7.18800  18.26400 31.40200  0.000 32.20000 ? 165 TRP A HZ3  1 
ATOM   2314 H HZ3  B TRP A 1 161 ? 7.05700  18.37500 31.30000  0.290 35.61000 ? 165 TRP A HZ3  1 
ATOM   2315 H HZ3  C TRP A 1 161 ? 7.20700  18.31700 31.32700  0.710 32.09000 ? 165 TRP A HZ3  1 
ATOM   2316 H HH2  A TRP A 1 161 ? 5.32000  19.51700 31.94200  0.000 32.28000 ? 165 TRP A HH2  1 
ATOM   2317 H HH2  B TRP A 1 161 ? 5.18100  19.60500 31.86400  0.290 35.62000 ? 165 TRP A HH2  1 
ATOM   2318 H HH2  C TRP A 1 161 ? 5.32400  19.57000 31.83000  0.710 32.48000 ? 165 TRP A HH2  1 
ATOM   2319 N N    A GLN A 1 162 ? 7.46600  12.63400 27.54700  0.000 28.04284 ? 166 GLN A N    1 
ATOM   2320 N N    B GLN A 1 162 ? 7.30000  12.51200 27.64300  0.420 30.06150 ? 166 GLN A N    1 
ATOM   2321 N N    C GLN A 1 162 ? 7.70300  12.92900 27.37800  0.580 25.87152 ? 166 GLN A N    1 
ATOM   2322 C CA   A GLN A 1 162 ? 8.35300  11.50700 27.28000  0.000 28.65080 ? 166 GLN A CA   1 
ATOM   2323 C CA   B GLN A 1 162 ? 8.08700  11.31400 27.39900  0.420 30.80369 ? 166 GLN A CA   1 
ATOM   2324 C CA   C GLN A 1 162 ? 8.67200  11.85600 27.15800  0.580 26.26894 ? 166 GLN A CA   1 
ATOM   2325 C C    A GLN A 1 162 ? 8.19800  10.47300 28.39400  0.000 28.61133 ? 166 GLN A C    1 
ATOM   2326 C C    B GLN A 1 162 ? 7.59500  10.18500 28.30000  0.420 31.43798 ? 166 GLN A C    1 
ATOM   2327 C C    C GLN A 1 162 ? 8.48400  10.81800 28.26300  0.580 26.64004 ? 166 GLN A C    1 
ATOM   2328 O O    A GLN A 1 162 ? 8.16800  10.82700 29.57600  0.000 28.59290 ? 166 GLN A O    1 
ATOM   2329 O O    B GLN A 1 162 ? 6.88100  10.41200 29.28200  0.420 31.93804 ? 166 GLN A O    1 
ATOM   2330 O O    C GLN A 1 162 ? 8.49200  11.17000 29.44600  0.580 25.11617 ? 166 GLN A O    1 
ATOM   2331 C CB   A GLN A 1 162 ? 9.80000  11.99200 27.17200  0.000 29.26404 ? 166 GLN A CB   1 
ATOM   2332 C CB   B GLN A 1 162 ? 9.55300  11.56800 27.74100  0.420 30.99845 ? 166 GLN A CB   1 
ATOM   2333 C CB   C GLN A 1 162 ? 10.09700 12.41100 27.19300  0.580 27.87703 ? 166 GLN A CB   1 
ATOM   2334 C CG   A GLN A 1 162 ? 10.48600 11.58200 25.86200  0.000 29.75357 ? 166 GLN A CG   1 
ATOM   2335 C CG   B GLN A 1 162 ? 10.10100 12.89000 27.25400  0.420 31.04846 ? 166 GLN A CG   1 
ATOM   2336 C CG   C GLN A 1 162 ? 11.09900 11.69900 26.28200  0.580 28.20601 ? 166 GLN A CG   1 
ATOM   2337 C CD   A GLN A 1 162 ? 11.46300 12.61800 25.30300  0.000 30.12203 ? 166 GLN A CD   1 
ATOM   2338 C CD   B GLN A 1 162 ? 11.03800 12.73100 26.07900  0.420 30.29311 ? 166 GLN A CD   1 
ATOM   2339 C CD   C GLN A 1 162 ? 10.88500 11.99500 24.80400  0.580 27.04535 ? 166 GLN A CD   1 
ATOM   2340 O OE1  A GLN A 1 162 ? 12.21700 12.32500 24.37400  0.000 30.22994 ? 166 GLN A OE1  1 
ATOM   2341 O OE1  B GLN A 1 162 ? 12.06900 13.39400 26.00800  0.420 31.04583 ? 166 GLN A OE1  1 
ATOM   2342 O OE1  C GLN A 1 162 ? 9.75400  11.99700 24.31300  0.580 27.92966 ? 166 GLN A OE1  1 
ATOM   2343 N NE2  A GLN A 1 162 ? 11.44500 13.83100 25.84700  0.000 30.25626 ? 166 GLN A NE2  1 
ATOM   2344 N NE2  B GLN A 1 162 ? 10.68800 11.84500 25.15100  0.420 29.78252 ? 166 GLN A NE2  1 
ATOM   2345 N NE2  C GLN A 1 162 ? 11.97600 12.24600 24.08700  0.580 26.20314 ? 166 GLN A NE2  1 
ATOM   2346 H HA   A GLN A 1 162 ? 8.12900  11.08200 26.43700  0.000 34.39000 ? 166 GLN A HA   1 
ATOM   2347 H HA   B GLN A 1 162 ? 8.00700  11.06300 26.46600  0.420 36.97000 ? 166 GLN A HA   1 
ATOM   2348 H HA   C GLN A 1 162 ? 8.54000  11.44400 26.29000  0.580 31.53000 ? 166 GLN A HA   1 
ATOM   2349 H HB2  A GLN A 1 162 ? 9.81000  12.96100 27.22300  0.000 35.13000 ? 166 GLN A HB2  1 
ATOM   2350 H HB2  B GLN A 1 162 ? 9.65100  11.55000 28.70600  0.420 37.21000 ? 166 GLN A HB2  1 
ATOM   2351 H HB2  C GLN A 1 162 ? 10.06900 13.34200 26.92100  0.580 33.46000 ? 166 GLN A HB2  1 
ATOM   2352 H HB3  A GLN A 1 162 ? 10.31100 11.61600 27.90500  0.000 35.13000 ? 166 GLN A HB3  1 
ATOM   2353 H HB3  B GLN A 1 162 ? 10.08800 10.86600 27.33900  0.420 37.21000 ? 166 GLN A HB3  1 
ATOM   2354 H HB3  C GLN A 1 162 ? 10.43000 12.34100 28.10100  0.580 33.46000 ? 166 GLN A HB3  1 
ATOM   2355 H HG2  A GLN A 1 162 ? 10.98500 10.76500 26.01700  0.000 35.71000 ? 166 GLN A HG2  1 
ATOM   2356 H HG2  B GLN A 1 162 ? 9.36400  13.45600 26.97700  0.420 37.27000 ? 166 GLN A HG2  1 
ATOM   2357 H HG2  C GLN A 1 162 ? 11.99500 11.98500 26.51700  0.580 33.85000 ? 166 GLN A HG2  1 
ATOM   2358 H HG3  A GLN A 1 162 ? 9.80300  11.43200 25.19000  0.000 35.71000 ? 166 GLN A HG3  1 
ATOM   2359 H HG3  B GLN A 1 162 ? 10.59200 13.31400 27.97500  0.420 37.27000 ? 166 GLN A HG3  1 
ATOM   2360 H HG3  C GLN A 1 162 ? 11.01300 10.74100 26.40900  0.580 33.85000 ? 166 GLN A HG3  1 
ATOM   2361 H HE21 A GLN A 1 162 ? 10.89800 14.00700 26.48800  0.000 36.31000 ? 166 GLN A HE21 1 
ATOM   2362 H HE21 B GLN A 1 162 ? 9.95900  11.39600 25.23700  0.420 35.75000 ? 166 GLN A HE21 1 
ATOM   2363 H HE21 C GLN A 1 162 ? 12.74900 12.23500 24.46300  0.580 31.45000 ? 166 GLN A HE21 1 
ATOM   2364 H HE22 A GLN A 1 162 ? 11.97900 14.44000 25.55900  0.000 36.31000 ? 166 GLN A HE22 1 
ATOM   2365 H HE22 B GLN A 1 162 ? 11.19000 11.72000 24.46400  0.420 35.75000 ? 166 GLN A HE22 1 
ATOM   2366 H HE22 C GLN A 1 162 ? 11.90900 12.41900 23.24700  0.580 31.45000 ? 166 GLN A HE22 1 
ATOM   2367 N N    A LEU A 1 163 ? 8.09500  9.19300  28.02800  0.480 28.52710 ? 167 LEU A N    1 
ATOM   2368 N N    B LEU A 1 163 ? 7.94100  8.94500  27.94400  0.290 31.21427 ? 167 LEU A N    1 
ATOM   2369 N N    C LEU A 1 163 ? 8.31100  9.54400  27.91500  0.230 27.89019 ? 167 LEU A N    1 
ATOM   2370 C CA   A LEU A 1 163 ? 8.30900  8.69500  26.67100  0.480 28.29287 ? 167 LEU A CA   1 
ATOM   2371 C CA   B LEU A 1 163 ? 8.41900  8.55900  26.61900  0.290 30.88791 ? 167 LEU A CA   1 
ATOM   2372 C CA   C LEU A 1 163 ? 8.53900  8.96800  26.59800  0.230 28.99295 ? 167 LEU A CA   1 
ATOM   2373 C C    A LEU A 1 163 ? 7.03100  8.36300  25.90200  0.480 27.04535 ? 167 LEU A C    1 
ATOM   2374 C C    B LEU A 1 163 ? 7.17500  8.21700  25.79900  0.290 29.77199 ? 167 LEU A C    1 
ATOM   2375 C C    C LEU A 1 163 ? 7.26200  8.70700  25.81000  0.230 28.14285 ? 167 LEU A C    1 
ATOM   2376 O O    A LEU A 1 163 ? 7.09400  7.89500  24.75600  0.480 24.53978 ? 167 LEU A O    1 
ATOM   2377 O O    B LEU A 1 163 ? 7.26400  7.72100  24.67200  0.290 29.06401 ? 167 LEU A O    1 
ATOM   2378 O O    C LEU A 1 163 ? 7.28400  7.98100  24.80700  0.230 26.91902 ? 167 LEU A O    1 
ATOM   2379 C CB   A LEU A 1 163 ? 9.17900  7.42900  26.73600  0.480 29.10086 ? 167 LEU A CB   1 
ATOM   2380 C CB   B LEU A 1 163 ? 9.34300  7.34500  26.71600  0.290 31.45114 ? 167 LEU A CB   1 
ATOM   2381 C CB   C LEU A 1 163 ? 9.27200  7.63200  26.79100  0.230 30.53261 ? 167 LEU A CB   1 
ATOM   2382 C CG   A LEU A 1 163 ? 10.54500 7.54200  27.41400  0.480 29.70093 ? 167 LEU A CG   1 
ATOM   2383 C CG   B LEU A 1 163 ? 10.71700 7.59600  27.34200  0.290 31.88277 ? 167 LEU A CG   1 
ATOM   2384 C CG   C LEU A 1 163 ? 10.64700 7.69600  27.45600  0.230 31.67748 ? 167 LEU A CG   1 
ATOM   2385 C CD1  A LEU A 1 163 ? 10.85100 6.32800  28.27400  0.480 30.09835 ? 167 LEU A CD1  1 
ATOM   2386 C CD1  B LEU A 1 163 ? 11.37600 6.27700  27.73000  0.290 31.89330 ? 167 LEU A CD1  1 
ATOM   2387 C CD1  C LEU A 1 163 ? 11.05000 6.38800  28.10400  0.230 32.05384 ? 167 LEU A CD1  1 
ATOM   2388 C CD2  A LEU A 1 163 ? 11.62600 7.72000  26.35300  0.480 29.59565 ? 167 LEU A CD2  1 
ATOM   2389 C CD2  B LEU A 1 163 ? 11.61500 8.38300  26.39500  0.290 31.94330 ? 167 LEU A CD2  1 
ATOM   2390 C CD2  C LEU A 1 163 ? 11.65500 8.09600  26.38500  0.230 31.89330 ? 167 LEU A CD2  1 
ATOM   2391 H HA   A LEU A 1 163 ? 8.74400  9.40500  26.17400  0.480 33.96000 ? 167 LEU A HA   1 
ATOM   2392 H HA   B LEU A 1 163 ? 8.93500  9.26200  26.19500  0.290 37.07000 ? 167 LEU A HA   1 
ATOM   2393 H HA   C LEU A 1 163 ? 9.05900  9.59800  26.07500  0.230 34.80000 ? 167 LEU A HA   1 
ATOM   2394 H HB2  A LEU A 1 163 ? 8.68100  6.75200  27.22100  0.480 34.93000 ? 167 LEU A HB2  1 
ATOM   2395 H HB2  B LEU A 1 163 ? 8.90100  6.67000  27.25500  0.290 37.75000 ? 167 LEU A HB2  1 
ATOM   2396 H HB2  C LEU A 1 163 ? 8.71500  7.06100  27.34400  0.230 36.65000 ? 167 LEU A HB2  1 
ATOM   2397 H HB3  A LEU A 1 163 ? 9.34100  7.13400  25.82600  0.480 34.93000 ? 167 LEU A HB3  1 
ATOM   2398 H HB3  B LEU A 1 163 ? 9.49400  7.00700  25.81900  0.290 37.75000 ? 167 LEU A HB3  1 
ATOM   2399 H HB3  C LEU A 1 163 ? 9.39600  7.22900  25.91800  0.230 36.65000 ? 167 LEU A HB3  1 
ATOM   2400 H HG   A LEU A 1 163 ? 10.53800 8.31400  28.00100  0.480 35.65000 ? 167 LEU A HG   1 
ATOM   2401 H HG   B LEU A 1 163 ? 10.59900 8.12600  28.14600  0.290 38.27000 ? 167 LEU A HG   1 
ATOM   2402 H HG   C LEU A 1 163 ? 10.62700 8.34600  28.17600  0.230 38.02000 ? 167 LEU A HG   1 
ATOM   2403 H HD11 A LEU A 1 163 ? 11.76400 6.39000  28.59500  0.480 36.13000 ? 167 LEU A HD11 1 
ATOM   2404 H HD11 B LEU A 1 163 ? 12.33700 6.40400  27.77100  0.290 38.28000 ? 167 LEU A HD11 1 
ATOM   2405 H HD11 C LEU A 1 163 ? 12.01700 6.35400  28.17200  0.230 38.47000 ? 167 LEU A HD11 1 
ATOM   2406 H HD12 A LEU A 1 163 ? 10.23700 6.31000  29.02500  0.480 36.13000 ? 167 LEU A HD12 1 
ATOM   2407 H HD12 B LEU A 1 163 ? 11.04200 5.99900  28.59700  0.290 38.28000 ? 167 LEU A HD12 1 
ATOM   2408 H HD12 C LEU A 1 163 ? 10.65400 6.33900  28.98800  0.230 38.47000 ? 167 LEU A HD12 1 
ATOM   2409 H HD13 A LEU A 1 163 ? 10.74200 5.52600  27.73900  0.480 36.13000 ? 167 LEU A HD13 1 
ATOM   2410 H HD13 B LEU A 1 163 ? 11.16000 5.60800  27.06200  0.290 38.28000 ? 167 LEU A HD13 1 
ATOM   2411 H HD13 C LEU A 1 163 ? 10.73100 5.65300  27.55700  0.230 38.47000 ? 167 LEU A HD13 1 
ATOM   2412 H HD21 A LEU A 1 163 ? 12.47800 7.86700  26.79200  0.480 35.52000 ? 167 LEU A HD21 1 
ATOM   2413 H HD21 B LEU A 1 163 ? 12.31300 8.81800  26.91000  0.290 38.34000 ? 167 LEU A HD21 1 
ATOM   2414 H HD21 C LEU A 1 163 ? 12.32200 8.67900  26.78100  0.230 38.28000 ? 167 LEU A HD21 1 
ATOM   2415 H HD22 A LEU A 1 163 ? 11.66900 6.91800  25.80900  0.480 35.52000 ? 167 LEU A HD22 1 
ATOM   2416 H HD22 B LEU A 1 163 ? 12.00900 7.77200  25.75300  0.290 38.34000 ? 167 LEU A HD22 1 
ATOM   2417 H HD22 C LEU A 1 163 ? 12.07900 7.29600  26.03600  0.230 38.28000 ? 167 LEU A HD22 1 
ATOM   2418 H HD23 A LEU A 1 163 ? 11.40300 8.48400  25.79900  0.480 35.52000 ? 167 LEU A HD23 1 
ATOM   2419 H HD23 B LEU A 1 163 ? 11.08200 9.04900  25.93400  0.290 38.34000 ? 167 LEU A HD23 1 
ATOM   2420 H HD23 C LEU A 1 163 ? 11.19100 8.56200  25.67200  0.230 38.28000 ? 167 LEU A HD23 1 
ATOM   2421 N N    A GLU A 1 164 ? 5.87600  8.61600  26.51900  0.610 27.56909 ? 168 GLU A N    1 
ATOM   2422 N N    B GLU A 1 164 ? 6.00600  8.49000  26.39000  0.390 28.97979 ? 168 GLU A N    1 
ATOM   2423 C CA   A GLU A 1 164 ? 4.60900  8.24200  25.89500  0.610 26.87691 ? 168 GLU A CA   1 
ATOM   2424 C CA   B GLU A 1 164 ? 4.73900  8.11000  25.77100  0.390 27.70332 ? 168 GLU A CA   1 
ATOM   2425 C C    A GLU A 1 164 ? 4.44800  8.85700  24.50500  0.610 24.13184 ? 168 GLU A C    1 
ATOM   2426 C C    B GLU A 1 164 ? 4.52700  8.80400  24.43100  0.390 24.73718 ? 168 GLU A C    1 
ATOM   2427 O O    A GLU A 1 164 ? 3.81500  8.25700  23.62800  0.610 24.07394 ? 168 GLU A O    1 
ATOM   2428 O O    B GLU A 1 164 ? 3.92500  8.22300  23.52100  0.390 24.67401 ? 168 GLU A O    1 
ATOM   2429 C CB   A GLU A 1 164 ? 3.44300  8.66800  26.79200  0.610 29.04559 ? 168 GLU A CB   1 
ATOM   2430 C CB   B GLU A 1 164 ? 3.57100  8.42700  26.70700  0.390 29.55618 ? 168 GLU A CB   1 
ATOM   2431 C CG   A GLU A 1 164 ? 3.24800  7.82100  28.05300  0.610 31.10373 ? 168 GLU A CG   1 
ATOM   2432 C CG   B GLU A 1 164 ? 3.49300  7.54900  27.95000  0.390 31.25375 ? 168 GLU A CG   1 
ATOM   2433 C CD   A GLU A 1 164 ? 4.22900  8.14900  29.16400  0.610 32.75656 ? 168 GLU A CD   1 
ATOM   2434 C CD   B GLU A 1 164 ? 2.06100  7.21900  28.34700  0.390 32.63549 ? 168 GLU A CD   1 
ATOM   2435 O OE1  A GLU A 1 164 ? 4.82000  9.25200  29.14800  0.610 32.36704 ? 168 GLU A OE1  1 
ATOM   2436 O OE1  B GLU A 1 164 ? 1.12300  7.88000  27.84800  0.390 33.31978 ? 168 GLU A OE1  1 
ATOM   2437 O OE2  A GLU A 1 164 ? 4.40200  7.29900  30.06500  0.610 34.73838 ? 168 GLU A OE2  1 
ATOM   2438 O OE2  B GLU A 1 164 ? 1.87400  6.28800  29.15700  0.390 32.92500 ? 168 GLU A OE2  1 
ATOM   2439 H H    A GLU A 1 164 ? 5.80000  8.99700  27.28600  0.480 33.09000 ? 168 GLU A H    1 
ATOM   2440 H H    B GLU A 1 164 ? 5.92300  8.89200  27.14600  0.290 34.78000 ? 168 GLU A H    1 
ATOM   2441 H HA   A GLU A 1 164 ? 4.59000  7.27700  25.79700  0.610 32.26000 ? 168 GLU A HA   1 
ATOM   2442 H HA   B GLU A 1 164 ? 4.75500  7.15200  25.61800  0.390 33.25000 ? 168 GLU A HA   1 
ATOM   2443 H HB2  A GLU A 1 164 ? 3.59500  9.58300  27.07700  0.610 34.86000 ? 168 GLU A HB2  1 
ATOM   2444 H HB2  B GLU A 1 164 ? 3.65600  9.34600  27.00400  0.390 35.47000 ? 168 GLU A HB2  1 
ATOM   2445 H HB3  A GLU A 1 164 ? 2.62400  8.61300  26.27600  0.610 34.86000 ? 168 GLU A HB3  1 
ATOM   2446 H HB3  B GLU A 1 164 ? 2.74300  8.31200  26.21600  0.390 35.47000 ? 168 GLU A HB3  1 
ATOM   2447 H HG2  A GLU A 1 164 ? 2.35300  7.97100  28.39500  0.610 37.33000 ? 168 GLU A HG2  1 
ATOM   2448 H HG2  B GLU A 1 164 ? 3.95600  6.71400  27.77700  0.390 37.51000 ? 168 GLU A HG2  1 
ATOM   2449 H HG3  A GLU A 1 164 ? 3.36300  6.88600  27.82300  0.610 37.33000 ? 168 GLU A HG3  1 
ATOM   2450 H HG3  B GLU A 1 164 ? 3.91100  8.01200  28.69200  0.390 37.51000 ? 168 GLU A HG3  1 
ATOM   2451 N N    . LEU A 1 165 ? 5.00600  10.04200 24.28200  1.000 22.12634 ? 169 LEU A N    1 
ATOM   2452 C CA   . LEU A 1 165 ? 4.80200  10.73200 23.01200  1.000 18.95490 ? 169 LEU A CA   1 
ATOM   2453 C C    . LEU A 1 165 ? 5.47600  10.03700 21.83500  1.000 17.88109 ? 169 LEU A C    1 
ATOM   2454 O O    . LEU A 1 165 ? 5.24300  10.45000 20.69200  1.000 18.29430 ? 169 LEU A O    1 
ATOM   2455 C CB   . LEU A 1 165 ? 5.26700  12.18200 23.11300  1.000 17.95742 ? 169 LEU A CB   1 
ATOM   2456 C CG   . LEU A 1 165 ? 6.77100  12.43300 23.21300  1.000 17.70212 ? 169 LEU A CG   1 
ATOM   2457 C CD1  . LEU A 1 165 ? 7.50000  12.41900 21.90400  1.000 19.35232 ? 169 LEU A CD1  1 
ATOM   2458 C CD2  . LEU A 1 165 ? 6.96500  13.78100 23.92300  1.000 19.15493 ? 169 LEU A CD2  1 
ATOM   2459 H H    A LEU A 1 165 ? 5.50100  10.46400 24.84400  0.610 26.56000 ? 169 LEU A H    1 
ATOM   2460 H H    B LEU A 1 165 ? 5.43500  10.48600 24.88000  0.390 26.56000 ? 169 LEU A H    1 
ATOM   2461 H HA   . LEU A 1 165 ? 3.85000  10.74600 22.82700  1.000 22.75000 ? 169 LEU A HA   1 
ATOM   2462 H HB2  . LEU A 1 165 ? 4.95700  12.64900 22.32100  1.000 21.56000 ? 169 LEU A HB2  1 
ATOM   2463 H HB3  . LEU A 1 165 ? 4.86400  12.56900 23.90600  1.000 21.56000 ? 169 LEU A HB3  1 
ATOM   2464 H HG   . LEU A 1 165 ? 7.16800  11.70100 23.71100  1.000 21.25000 ? 169 LEU A HG   1 
ATOM   2465 H HD11 . LEU A 1 165 ? 8.34000  12.89200 22.00600  1.000 23.23000 ? 169 LEU A HD11 1 
ATOM   2466 H HD12 . LEU A 1 165 ? 7.66800  11.49900 21.64600  1.000 23.23000 ? 169 LEU A HD12 1 
ATOM   2467 H HD13 . LEU A 1 165 ? 6.95300  12.85600 21.23300  1.000 23.23000 ? 169 LEU A HD13 1 
ATOM   2468 H HD21 . LEU A 1 165 ? 7.91000  13.91200 24.09800  1.000 23.00000 ? 169 LEU A HD21 1 
ATOM   2469 H HD22 . LEU A 1 165 ? 6.63300  14.49000 23.35100  1.000 23.00000 ? 169 LEU A HD22 1 
ATOM   2470 H HD23 . LEU A 1 165 ? 6.47200  13.77200 24.75900  1.000 23.00000 ? 169 LEU A HD23 1 
ATOM   2471 N N    . ASN A 1 166 ? 6.26300  8.98400  22.06300  1.000 16.59146 ? 170 ASN A N    1 
ATOM   2472 C CA   . ASN A 1 166 ? 6.99300  8.29400  20.99500  1.000 15.48607 ? 170 ASN A CA   1 
ATOM   2473 C C    . ASN A 1 166 ? 6.30100  7.01900  20.50900  1.000 14.80441 ? 170 ASN A C    1 
ATOM   2474 O O    . ASN A 1 166 ? 6.92100  6.23100  19.78200  1.000 15.81242 ? 170 ASN A O    1 
ATOM   2475 C CB   . ASN A 1 166 ? 8.41300  7.96300  21.46100  1.000 16.14404 ? 170 ASN A CB   1 
ATOM   2476 C CG   . ASN A 1 166 ? 9.16400  9.18400  21.89500  1.000 18.08638 ? 170 ASN A CG   1 
ATOM   2477 O OD1  . ASN A 1 166 ? 9.73000  9.88300  21.07900  1.000 18.65224 ? 170 ASN A OD1  1 
ATOM   2478 N ND2  . ASN A 1 166 ? 9.18600  9.43600  23.20700  1.000 19.13650 ? 170 ASN A ND2  1 
ATOM   2479 H H    . ASN A 1 166 ? 6.39200  8.64300  22.84200  1.000 19.92000 ? 170 ASN A H    1 
ATOM   2480 H HA   . ASN A 1 166 ? 7.04400  8.90000  20.24000  1.000 18.59000 ? 170 ASN A HA   1 
ATOM   2481 H HB2  . ASN A 1 166 ? 8.36800  7.35200  22.21300  1.000 19.38000 ? 170 ASN A HB2  1 
ATOM   2482 H HB3  . ASN A 1 166 ? 8.90000  7.55200  20.73000  1.000 19.38000 ? 170 ASN A HB3  1 
ATOM   2483 H HD21 . ASN A 1 166 ? 9.60500  10.12500 23.50600  1.000 22.97000 ? 170 ASN A HD21 1 
ATOM   2484 H HD22 . ASN A 1 166 ? 8.78300  8.90800  23.75300  1.000 22.97000 ? 170 ASN A HD22 1 
ATOM   2485 N N    . SER A 1 167 ? 5.01400  6.82900  20.83800  1.000 14.88073 ? 171 SER A N    1 
ATOM   2486 C CA   . SER A 1 167 ? 4.32200  5.59400  20.47500  1.000 14.97548 ? 171 SER A CA   1 
ATOM   2487 C C    . SER A 1 167 ? 4.18600  5.40800  18.96600  1.000 13.92272 ? 171 SER A C    1 
ATOM   2488 O O    . SER A 1 167 ? 4.11900  4.26700  18.49800  1.000 14.70703 ? 171 SER A O    1 
ATOM   2489 C CB   . SER A 1 167 ? 2.96000  5.52000  21.18200  1.000 17.33366 ? 171 SER A CB   1 
ATOM   2490 O OG   . SER A 1 167 ? 2.20000  6.69200  20.98200  1.000 17.68370 ? 171 SER A OG   1 
ATOM   2491 H H    . SER A 1 167 ? 4.52900  7.39500  21.26600  1.000 17.87000 ? 171 SER A H    1 
ATOM   2492 H HA   . SER A 1 167 ? 4.85300  4.84700  20.79000  1.000 17.98000 ? 171 SER A HA   1 
ATOM   2493 H HB2  . SER A 1 167 ? 2.46600  4.76300  20.82900  1.000 20.81000 ? 171 SER A HB2  1 
ATOM   2494 H HB3  . SER A 1 167 ? 3.10900  5.40300  22.13400  1.000 20.81000 ? 171 SER A HB3  1 
ATOM   2495 H HG   . SER A 1 167 ? 2.01600  6.77900  20.16700  1.000 21.23000 ? 171 SER A HG   1 
ATOM   2496 N N    . ALA A 1 168 ? 4.13600  6.49400  18.19900  1.000 14.23065 ? 172 ALA A N    1 
ATOM   2497 C CA   . ALA A 1 168 ? 4.20400  6.42100  16.74200  1.000 13.81218 ? 172 ALA A CA   1 
ATOM   2498 C C    . ALA A 1 168 ? 3.11000  5.52800  16.13800  1.000 13.55689 ? 172 ALA A C    1 
ATOM   2499 O O    . ALA A 1 168 ? 3.31400  4.84200  15.12600  1.000 13.93325 ? 172 ALA A O    1 
ATOM   2500 C CB   . ALA A 1 168 ? 5.60600  5.99300  16.29600  1.000 13.15684 ? 172 ALA A CB   1 
ATOM   2501 H H    . ALA A 1 168 ? 4.06100  7.29500  18.50200  1.000 17.09000 ? 172 ALA A H    1 
ATOM   2502 H HA   . ALA A 1 168 ? 4.03100  7.30700  16.38600  1.000 16.58000 ? 172 ALA A HA   1 
ATOM   2503 H HB1  . ALA A 1 168 ? 5.62800  5.94300  15.32700  1.000 15.79000 ? 172 ALA A HB1  1 
ATOM   2504 H HB2  . ALA A 1 168 ? 6.25100  6.64600  16.60800  1.000 15.79000 ? 172 ALA A HB2  1 
ATOM   2505 H HB3  . ALA A 1 168 ? 5.80600  5.12300  16.67600  1.000 15.79000 ? 172 ALA A HB3  1 
ATOM   2506 N N    . ILE A 1 169 ? 1.92800  5.56300  16.74100  1.000 13.32002 ? 173 ILE A N    1 
ATOM   2507 C CA   . ILE A 1 169 ? 0.83700  4.69300  16.31000  1.000 13.08052 ? 173 ILE A CA   1 
ATOM   2508 C C    . ILE A 1 169 ? 0.36400  5.11000  14.92000  1.000 13.09368 ? 173 ILE A C    1 
ATOM   2509 O O    . ILE A 1 169 ? 0.06300  6.29800  14.69000  1.000 13.64637 ? 173 ILE A O    1 
ATOM   2510 C CB   . ILE A 1 169 ? -0.31400 4.75700  17.32000  1.000 13.71480 ? 173 ILE A CB   1 
ATOM   2511 C CG1  . ILE A 1 169 ? 0.14100  4.16500  18.64400  1.000 16.04929 ? 173 ILE A CG1  1 
ATOM   2512 C CG2  . ILE A 1 169 ? -1.55100 4.05900  16.76500  1.000 13.95167 ? 173 ILE A CG2  1 
ATOM   2513 C CD1  . ILE A 1 169 ? -0.77600 4.49500  19.81100  1.000 17.87846 ? 173 ILE A CD1  1 
ATOM   2514 H H    . ILE A 1 169 ? 1.73100  6.07800  17.40100  1.000 16.00000 ? 173 ILE A H    1 
ATOM   2515 H HA   . ILE A 1 169 ? 1.15900  3.77900  16.25600  1.000 15.70000 ? 173 ILE A HA   1 
ATOM   2516 H HB   . ILE A 1 169 ? -0.56000 5.68300  17.47700  1.000 16.46000 ? 173 ILE A HB   1 
ATOM   2517 H HG12 . ILE A 1 169 ? 0.17600  3.19900  18.55800  1.000 19.27000 ? 173 ILE A HG12 1 
ATOM   2518 H HG13 . ILE A 1 169 ? 1.02300  4.51100  18.85400  1.000 19.27000 ? 173 ILE A HG13 1 
ATOM   2519 H HG21 . ILE A 1 169 ? -2.14800 3.84500  17.49800  1.000 16.75000 ? 173 ILE A HG21 1 
ATOM   2520 H HG22 . ILE A 1 169 ? -1.99400 4.65200  16.13900  1.000 16.75000 ? 173 ILE A HG22 1 
ATOM   2521 H HG23 . ILE A 1 169 ? -1.27800 3.24500  16.31300  1.000 16.75000 ? 173 ILE A HG23 1 
ATOM   2522 H HD11 . ILE A 1 169 ? -0.35300 4.21000  20.63600  1.000 21.46000 ? 173 ILE A HD11 1 
ATOM   2523 H HD12 . ILE A 1 169 ? -0.93000 5.45200  19.83100  1.000 21.46000 ? 173 ILE A HD12 1 
ATOM   2524 H HD13 . ILE A 1 169 ? -1.61800 4.02700  19.69200  1.000 21.46000 ? 173 ILE A HD13 1 
ATOM   2525 N N    . PRO A 1 170 ? 0.23700  4.17400  13.98600  1.000 12.26989 ? 174 PRO A N    1 
ATOM   2526 C CA   . PRO A 1 170 ? -0.27500 4.52500  12.65300  1.000 12.39622 ? 174 PRO A CA   1 
ATOM   2527 C C    . PRO A 1 170 ? -1.62100 5.23800  12.70700  1.000 12.46992 ? 174 PRO A C    1 
ATOM   2528 O O    . PRO A 1 170 ? -2.57600 4.76600  13.33000  1.000 13.68848 ? 174 PRO A O    1 
ATOM   2529 C CB   . PRO A 1 170 ? -0.37900 3.16300  11.95900  1.000 13.84113 ? 174 PRO A CB   1 
ATOM   2530 C CG   . PRO A 1 170 ? 0.66400  2.31400  12.63900  1.000 15.29394 ? 174 PRO A CG   1 
ATOM   2531 C CD   . PRO A 1 170 ? 0.63900  2.76100  14.07500  1.000 13.29107 ? 174 PRO A CD   1 
ATOM   2532 H HA   . PRO A 1 170 ? 0.35900  5.09400  12.18900  1.000 14.88000 ? 174 PRO A HA   1 
ATOM   2533 H HB2  . PRO A 1 170 ? -1.26700 2.79300  12.08500  1.000 16.61000 ? 174 PRO A HB2  1 
ATOM   2534 H HB3  . PRO A 1 170 ? -0.19000 3.25600  11.01200  1.000 16.61000 ? 174 PRO A HB3  1 
ATOM   2535 H HG2  . PRO A 1 170 ? 0.43000  1.37600  12.56300  1.000 18.36000 ? 174 PRO A HG2  1 
ATOM   2536 H HG3  . PRO A 1 170 ? 1.53300  2.47300  12.24000  1.000 18.36000 ? 174 PRO A HG3  1 
ATOM   2537 H HD2  . PRO A 1 170 ? -0.00900 2.24900  14.58400  1.000 15.96000 ? 174 PRO A HD2  1 
ATOM   2538 H HD3  . PRO A 1 170 ? 1.51800  2.67700  14.47700  1.000 15.96000 ? 174 PRO A HD3  1 
ATOM   2539 N N    . GLY A 1 171 ? -1.69100 6.38600  12.03600  1.000 13.18579 ? 175 GLY A N    1 
ATOM   2540 C CA   . GLY A 1 171 ? -2.91500 7.17000  11.95000  1.000 13.72533 ? 175 GLY A CA   1 
ATOM   2541 C C    . GLY A 1 171 ? -3.15100 8.12200  13.11200  1.000 14.05695 ? 175 GLY A C    1 
ATOM   2542 O O    . GLY A 1 171 ? -4.04900 8.95800  13.03200  1.000 15.19919 ? 175 GLY A O    1 
ATOM   2543 H H    . GLY A 1 171 ? -1.02900 6.73700  11.61400  1.000 15.83000 ? 175 GLY A H    1 
ATOM   2544 H HA2  . GLY A 1 171 ? -2.88800 7.69800  11.13700  1.000 16.48000 ? 175 GLY A HA2  1 
ATOM   2545 H HA3  . GLY A 1 171 ? -3.66900 6.56200  11.90800  1.000 16.48000 ? 175 GLY A HA3  1 
ATOM   2546 N N    . ASP A 1 172 ? -2.33600 8.05700  14.16300  1.000 13.23317 ? 176 ASP A N    1 
ATOM   2547 C CA   . ASP A 1 172 ? -2.50500 8.89400  15.34500  1.000 13.11999 ? 176 ASP A CA   1 
ATOM   2548 C C    . ASP A 1 172 ? -1.82000 10.23000 15.08200  1.000 12.57256 ? 176 ASP A C    1 
ATOM   2549 O O    . ASP A 1 172 ? -0.61700 10.27700 14.81900  1.000 13.88851 ? 176 ASP A O    1 
ATOM   2550 C CB   . ASP A 1 172 ? -1.88100 8.15000  16.53000  1.000 13.88324 ? 176 ASP A CB   1 
ATOM   2551 C CG   . ASP A 1 172 ? -2.09800 8.82400  17.88500  1.000 15.26499 ? 176 ASP A CG   1 
ATOM   2552 O OD1  . ASP A 1 172 ? -2.61500 9.95600  17.97100  1.000 15.06233 ? 176 ASP A OD1  1 
ATOM   2553 O OD2  . ASP A 1 172 ? -1.65700 8.19300  18.86300  1.000 16.70727 ? 176 ASP A OD2  1 
ATOM   2554 H H    . ASP A 1 172 ? -1.66300 7.52400  14.21500  1.000 15.89000 ? 176 ASP A H    1 
ATOM   2555 H HA   . ASP A 1 172 ? -3.43700 9.07600  15.54500  1.000 15.75000 ? 176 ASP A HA   1 
ATOM   2556 H HB2  . ASP A 1 172 ? -2.27000 7.26300  16.57800  1.000 16.67000 ? 176 ASP A HB2  1 
ATOM   2557 H HB3  . ASP A 1 172 ? -0.92400 8.08600  16.38500  1.000 16.67000 ? 176 ASP A HB3  1 
ATOM   2558 N N    . ALA A 1 173 ? -2.59000 11.31900 15.10700  1.000 12.63046 ? 177 ALA A N    1 
ATOM   2559 C CA   . ALA A 1 173 ? -2.04300 12.65200 14.90100  1.000 13.55426 ? 177 ALA A CA   1 
ATOM   2560 C C    . ALA A 1 173 ? -1.31300 13.20900 16.12500  1.000 12.56466 ? 177 ALA A C    1 
ATOM   2561 O O    . ALA A 1 173 ? -0.64600 14.24300 16.01400  1.000 12.66994 ? 177 ALA A O    1 
ATOM   2562 C CB   . ALA A 1 173 ? -3.12300 13.64000 14.43600  1.000 13.85692 ? 177 ALA A CB   1 
ATOM   2563 H H    . ALA A 1 173 ? -3.43900 11.30800 15.24400  1.000 15.17000 ? 177 ALA A H    1 
ATOM   2564 H HA   . ALA A 1 173 ? -1.39700 12.58900 14.18000  1.000 16.27000 ? 177 ALA A HA   1 
ATOM   2565 H HB1  . ALA A 1 173 ? -2.72100 14.51500 14.31900  1.000 16.64000 ? 177 ALA A HB1  1 
ATOM   2566 H HB2  . ALA A 1 173 ? -3.49300 13.33100 13.59400  1.000 16.64000 ? 177 ALA A HB2  1 
ATOM   2567 H HB3  . ALA A 1 173 ? -3.82200 13.68300 15.10700  1.000 16.64000 ? 177 ALA A HB3  1 
ATOM   2568 N N    . ARG A 1 174 ? -1.47700 12.60900 17.30400  1.000 12.12251 ? 178 ARG A N    1 
ATOM   2569 C CA   . ARG A 1 174 ? -0.80800 13.16100 18.47500  1.000 12.11198 ? 178 ARG A CA   1 
ATOM   2570 C C    . ARG A 1 174 ? 0.70200  13.18400 18.27200  1.000 11.46980 ? 178 ARG A C    1 
ATOM   2571 O O    . ARG A 1 174 ? 1.27400  12.24900 17.72200  1.000 12.59625 ? 178 ARG A O    1 
ATOM   2572 C CB   . ARG A 1 174 ? -1.15900 12.34300 19.71600  1.000 13.78323 ? 178 ARG A CB   1 
ATOM   2573 C CG   . ARG A 1 174 ? -2.60500 12.53900 20.18700  1.000 14.77019 ? 178 ARG A CG   1 
ATOM   2574 C CD   . ARG A 1 174 ? -2.89300 11.64400 21.38700  1.000 16.82570 ? 178 ARG A CD   1 
ATOM   2575 N NE   . ARG A 1 174 ? -2.74300 10.23600 21.06000  1.000 18.49432 ? 178 ARG A NE   1 
ATOM   2576 C CZ   . ARG A 1 174 ? -2.74900 9.24900  21.94300  1.000 20.72091 ? 178 ARG A CZ   1 
ATOM   2577 N NH1  . ARG A 1 174 ? -2.97100 9.47400  23.23300  1.000 22.93696 ? 178 ARG A NH1  1 
ATOM   2578 N NH2  . ARG A 1 174 ? -2.51800 8.00800  21.52500  1.000 21.74208 ? 178 ARG A NH2  1 
ATOM   2579 H H    . ARG A 1 174 ? -1.95400 11.90700 17.44500  1.000 14.55000 ? 178 ARG A H    1 
ATOM   2580 H HA   . ARG A 1 174 ? -1.10800 14.07300 18.61500  1.000 14.54000 ? 178 ARG A HA   1 
ATOM   2581 H HB2  . ARG A 1 174 ? -1.03600 11.40200 19.51600  1.000 16.55000 ? 178 ARG A HB2  1 
ATOM   2582 H HB3  . ARG A 1 174 ? -0.57200 12.60800 20.44200  1.000 16.55000 ? 178 ARG A HB3  1 
ATOM   2583 H HG2  . ARG A 1 174 ? -2.74000 13.46300 20.44900  1.000 17.73000 ? 178 ARG A HG2  1 
ATOM   2584 H HG3  . ARG A 1 174 ? -3.21500 12.30400 19.47100  1.000 17.73000 ? 178 ARG A HG3  1 
ATOM   2585 H HD2  . ARG A 1 174 ? -2.27300 11.85700 22.10200  1.000 20.20000 ? 178 ARG A HD2  1 
ATOM   2586 H HD3  . ARG A 1 174 ? -3.80500 11.79100 21.68400  1.000 20.20000 ? 178 ARG A HD3  1 
ATOM   2587 H HE   . ARG A 1 174 ? -2.64300 10.02800 20.23100  1.000 22.20000 ? 178 ARG A HE   1 
ATOM   2588 H HH11 . ARG A 1 174 ? -3.11500 10.27500 23.51100  1.000 27.53000 ? 178 ARG A HH11 1 
ATOM   2589 H HH12 . ARG A 1 174 ? -2.97000 8.81900  23.79000  1.000 27.53000 ? 178 ARG A HH12 1 
ATOM   2590 H HH21 . ARG A 1 174 ? -2.36900 7.85500  20.69200  1.000 26.10000 ? 178 ARG A HH21 1 
ATOM   2591 H HH22 . ARG A 1 174 ? -2.51900 7.35700  22.08800  1.000 26.10000 ? 178 ARG A HH22 1 
ATOM   2592 N N    . ASP A 1 175 ? 1.33400  14.26700 18.71100  1.000 11.90143 ? 179 ASP A N    1 
ATOM   2593 C CA   . ASP A 1 175 ? 2.80000  14.34600 18.73500  1.000 11.73562 ? 179 ASP A CA   1 
ATOM   2594 C C    . ASP A 1 175 ? 3.38500  14.18200 17.33900  1.000 11.16976 ? 179 ASP A C    1 
ATOM   2595 O O    . ASP A 1 175 ? 4.38500  13.49800 17.13800  1.000 11.79352 ? 179 ASP A O    1 
ATOM   2596 C CB   . ASP A 1 175 ? 3.36700  13.31800 19.69900  1.000 11.52770 ? 179 ASP A CB   1 
ATOM   2597 C CG   . ASP A 1 175 ? 2.72200  13.43100 21.07200  1.000 14.46752 ? 179 ASP A CG   1 
ATOM   2598 O OD1  . ASP A 1 175 ? 2.90600  14.49400 21.70400  1.000 14.72545 ? 179 ASP A OD1  1 
ATOM   2599 O OD2  . ASP A 1 175 ? 2.00400  12.48700 21.49400  1.000 15.34658 ? 179 ASP A OD2  1 
ATOM   2600 H H    . ASP A 1 175 ? 0.94000  14.97400 19.00300  1.000 14.29000 ? 179 ASP A H    1 
ATOM   2601 H HA   . ASP A 1 175 ? 3.06600  15.22600 19.04400  1.000 14.09000 ? 179 ASP A HA   1 
ATOM   2602 H HB2  . ASP A 1 175 ? 3.20000  12.42700 19.35500  1.000 13.84000 ? 179 ASP A HB2  1 
ATOM   2603 H HB3  . ASP A 1 175 ? 4.32200  13.46200 19.79700  1.000 13.84000 ? 179 ASP A HB3  1 
ATOM   2604 N N    . THR A 1 176 ? 2.74800  14.85100 16.37900  1.000 11.68035 ? 180 THR A N    1 
ATOM   2605 C CA   . THR A 1 176 ? 3.20800  14.82900 14.99400  1.000 11.87774 ? 180 THR A CA   1 
ATOM   2606 C C    . THR A 1 176 ? 3.33500  16.23600 14.44000  1.000 11.57770 ? 180 THR A C    1 
ATOM   2607 O O    . THR A 1 176 ? 2.76700  17.20900 14.94300  1.000 11.62771 ? 180 THR A O    1 
ATOM   2608 C CB   . THR A 1 176 ? 2.22600  14.07300 14.05400  1.000 12.13830 ? 180 THR A CB   1 
ATOM   2609 O OG1  . THR A 1 176 ? 0.97800  14.78900 14.01400  1.000 12.43570 ? 180 THR A OG1  1 
ATOM   2610 C CG2  . THR A 1 176 ? 2.03100  12.63600 14.46100  1.000 12.39359 ? 180 THR A CG2  1 
ATOM   2611 H H    . THR A 1 176 ? 2.04300  15.32700 16.50700  1.000 14.03000 ? 180 THR A H    1 
ATOM   2612 H HA   . THR A 1 176 ? 4.07500  14.39500 14.99700  1.000 14.26000 ? 180 THR A HA   1 
ATOM   2613 H HB   . THR A 1 176 ? 2.59900  14.03300 13.15900  1.000 14.58000 ? 180 THR A HB   1 
ATOM   2614 H HG1  . THR A 1 176 ? 0.64900  14.83800 14.78500  1.000 14.93000 ? 180 THR A HG1  1 
ATOM   2615 H HG21 . THR A 1 176 ? 1.36600  12.21700 13.89300  1.000 14.88000 ? 180 THR A HG21 1 
ATOM   2616 H HG22 . THR A 1 176 ? 2.86700  12.15100 14.37800  1.000 14.88000 ? 180 THR A HG22 1 
ATOM   2617 H HG23 . THR A 1 176 ? 1.73100  12.59000 15.38300  1.000 14.88000 ? 180 THR A HG23 1 
ATOM   2618 N N    . SER A 1 177 ? 4.06500  16.31300 13.33000  1.000 11.01711 ? 181 SER A N    1 
ATOM   2619 C CA   . SER A 1 177 ? 3.96100  17.46800 12.45500  1.000 10.96710 ? 181 SER A CA   1 
ATOM   2620 C C    . SER A 1 177 ? 4.17500  16.96900 11.02900  1.000 10.80130 ? 181 SER A C    1 
ATOM   2621 O O    . SER A 1 177 ? 4.21300  15.76000 10.80500  1.000 11.14607 ? 181 SER A O    1 
ATOM   2622 C CB   . SER A 1 177 ? 4.92100  18.60100 12.82900  1.000 11.53296 ? 181 SER A CB   1 
ATOM   2623 O OG   . SER A 1 177 ? 4.54600  19.78700 12.16800  1.000 11.19345 ? 181 SER A OG   1 
ATOM   2624 H H    . SER A 1 177 ? 4.62200  15.71300 13.06700  1.000 13.23000 ? 181 SER A H    1 
ATOM   2625 H HA   . SER A 1 177 ? 3.06800  17.83400 12.55100  1.000 13.17000 ? 181 SER A HA   1 
ATOM   2626 H HB2  . SER A 1 177 ? 4.88700  18.74500 13.78700  1.000 13.85000 ? 181 SER A HB2  1 
ATOM   2627 H HB3  . SER A 1 177 ? 5.82100  18.35700 12.56200  1.000 13.85000 ? 181 SER A HB3  1 
ATOM   2628 H HG   . SER A 1 177 ? 5.06400  20.41200 12.38200  1.000 13.44000 ? 181 SER A HG   1 
ATOM   2629 N N    . SER A 1 178 ? 4.31400  17.90000 10.07000  1.000 10.72234 ? 182 SER A N    1 
ATOM   2630 C CA   . SER A 1 178 ? 4.62000  17.50300 8.70800   1.000 10.10384 ? 182 SER A CA   1 
ATOM   2631 C C    . SER A 1 178 ? 6.02700  17.93700 8.38400   1.000 10.69865 ? 182 SER A C    1 
ATOM   2632 O O    . SER A 1 178 ? 6.53100  18.91300 8.95200   1.000 10.80656 ? 182 SER A O    1 
ATOM   2633 C CB   . SER A 1 178 ? 3.67300  18.19800 7.71500   1.000 10.04068 ? 182 SER A CB   1 
ATOM   2634 O OG   . SER A 1 178 ? 3.85800  19.58200 7.73000   1.000 10.78024 ? 182 SER A OG   1 
ATOM   2635 H H    . SER A 1 178 ? 4.23400  18.74700 10.19300  1.000 12.88000 ? 182 SER A H    1 
ATOM   2636 H HA   . SER A 1 178 ? 4.52300  16.54400 8.60900   1.000 12.13000 ? 182 SER A HA   1 
ATOM   2637 H HB2  . SER A 1 178 ? 3.85400  17.86500 6.82200   1.000 12.05000 ? 182 SER A HB2  1 
ATOM   2638 H HB3  . SER A 1 178 ? 2.75600  18.00000 7.96400   1.000 12.05000 ? 182 SER A HB3  1 
ATOM   2639 H HG   . SER A 1 178 ? 3.29100  19.95300 7.23400   1.000 12.94000 ? 182 SER A HG   1 
ATOM   2640 N N    . PRO A 1 179 ? 6.66500  17.29300 7.39500   1.000 10.95131 ? 183 PRO A N    1 
ATOM   2641 C CA   . PRO A 1 179 ? 8.00100  17.76600 6.98300   1.000 11.88037 ? 183 PRO A CA   1 
ATOM   2642 C C    . PRO A 1 179 ? 8.01000  19.22200 6.56400   1.000 11.58560 ? 183 PRO A C    1 
ATOM   2643 O O    . PRO A 1 179 ? 8.94600  19.97700 6.87400   1.000 11.92775 ? 183 PRO A O    1 
ATOM   2644 C CB   . PRO A 1 179 ? 8.34800  16.82600 5.83100   1.000 12.20146 ? 183 PRO A CB   1 
ATOM   2645 C CG   . PRO A 1 179 ? 7.62000  15.55100 6.15500   1.000 12.01460 ? 183 PRO A CG   1 
ATOM   2646 C CD   . PRO A 1 179 ? 6.31200  16.00400 6.76700   1.000 11.18818 ? 183 PRO A CD   1 
ATOM   2647 H HA   . PRO A 1 179 ? 8.64200  17.63900 7.70000   1.000 14.26000 ? 183 PRO A HA   1 
ATOM   2648 H HB2  . PRO A 1 179 ? 8.03900  17.20100 4.99200   1.000 14.65000 ? 183 PRO A HB2  1 
ATOM   2649 H HB3  . PRO A 1 179 ? 9.30700  16.68100 5.79700   1.000 14.65000 ? 183 PRO A HB3  1 
ATOM   2650 H HG2  . PRO A 1 179 ? 7.46700  15.04100 5.34400   1.000 14.43000 ? 183 PRO A HG2  1 
ATOM   2651 H HG3  . PRO A 1 179 ? 8.13600  15.02500 6.78600   1.000 14.43000 ? 183 PRO A HG3  1 
ATOM   2652 H HD2  . PRO A 1 179 ? 5.63500  16.12600 6.08300   1.000 13.43000 ? 183 PRO A HD2  1 
ATOM   2653 H HD3  . PRO A 1 179 ? 6.00200  15.36900 7.43100   1.000 13.43000 ? 183 PRO A HD3  1 
ATOM   2654 N N    . ARG A 1 180 ? 6.95400  19.64700 5.86800   1.000 11.78826 ? 184 ARG A N    1 
ATOM   2655 C CA   . ARG A 1 180 ? 6.87300  21.03300 5.43900   1.000 11.95670 ? 184 ARG A CA   1 
ATOM   2656 C C    . ARG A 1 180 ? 6.82700  21.98900 6.62300   1.000 11.40663 ? 184 ARG A C    1 
ATOM   2657 O O    . ARG A 1 180 ? 7.53500  22.99700 6.64500   1.000 12.09619 ? 184 ARG A O    1 
ATOM   2658 C CB   . ARG A 1 180 ? 5.67800  21.22900 4.51700   1.000 12.80943 ? 184 ARG A CB   1 
ATOM   2659 C CG   . ARG A 1 180 ? 5.47800  22.65200 4.10300   1.000 13.43845 ? 184 ARG A CG   1 
ATOM   2660 C CD   . ARG A 1 180 ? 4.54900  22.72800 2.92400   1.000 15.18077 ? 184 ARG A CD   1 
ATOM   2661 N NE   . ARG A 1 180 ? 4.39700  24.08300 2.43600   1.000 16.55988 ? 184 ARG A NE   1 
ATOM   2662 C CZ   . ARG A 1 180 ? 3.75300  24.37100 1.31800   1.000 19.77079 ? 184 ARG A CZ   1 
ATOM   2663 N NH1  . ARG A 1 180 ? 3.15800  23.42600 0.61800   1.000 20.17084 ? 184 ARG A NH1  1 
ATOM   2664 N NH2  . ARG A 1 180 ? 3.72400  25.62800 0.88800   1.000 21.73418 ? 184 ARG A NH2  1 
ATOM   2665 H H    . ARG A 1 180 ? 6.28500  19.15800 5.63700   1.000 14.15000 ? 184 ARG A H    1 
ATOM   2666 H HA   . ARG A 1 180 ? 7.67200  21.24500 4.93200   1.000 14.35000 ? 184 ARG A HA   1 
ATOM   2667 H HB2  . ARG A 1 180 ? 5.81200  20.70100 3.71400   1.000 15.38000 ? 184 ARG A HB2  1 
ATOM   2668 H HB3  . ARG A 1 180 ? 4.87600  20.93600 4.97600   1.000 15.38000 ? 184 ARG A HB3  1 
ATOM   2669 H HG2  . ARG A 1 180 ? 5.08900  23.15300 4.83700   1.000 16.13000 ? 184 ARG A HG2  1 
ATOM   2670 H HG3  . ARG A 1 180 ? 6.33000  23.04100 3.85100   1.000 16.13000 ? 184 ARG A HG3  1 
ATOM   2671 H HD2  . ARG A 1 180 ? 4.90400  22.18500 2.20300   1.000 18.23000 ? 184 ARG A HD2  1 
ATOM   2672 H HD3  . ARG A 1 180 ? 3.67400  22.40100 3.18600   1.000 18.23000 ? 184 ARG A HD3  1 
ATOM   2673 H HE   . ARG A 1 180 ? 4.74000  24.72700 2.89200   1.000 19.88000 ? 184 ARG A HE   1 
ATOM   2674 H HH11 . ARG A 1 180 ? 3.18600  22.60900 0.88700   1.000 24.21000 ? 184 ARG A HH11 1 
ATOM   2675 H HH12 . ARG A 1 180 ? 2.74200  23.62500 -0.10800  1.000 24.21000 ? 184 ARG A HH12 1 
ATOM   2676 H HH21 . ARG A 1 180 ? 4.12200  26.24500 1.33700   1.000 26.09000 ? 184 ARG A HH21 1 
ATOM   2677 H HH22 . ARG A 1 180 ? 3.30700  25.82500 0.16200   1.000 26.09000 ? 184 ARG A HH22 1 
ATOM   2678 N N    . ALA A 1 181 ? 5.93500  21.74300 7.58800   1.000 11.32767 ? 185 ALA A N    1 
ATOM   2679 C CA   . ALA A 1 181 ? 5.83300  22.66500 8.71400   1.000 12.38306 ? 185 ALA A CA   1 
ATOM   2680 C C    . ALA A 1 181 ? 7.10200  22.66600 9.55700   1.000 11.94617 ? 185 ALA A C    1 
ATOM   2681 O O    . ALA A 1 181 ? 7.51100  23.71900 10.05700  1.000 12.63573 ? 185 ALA A O    1 
ATOM   2682 C CB   . ALA A 1 181 ? 4.62700  22.30700 9.57500   1.000 12.05671 ? 185 ALA A CB   1 
ATOM   2683 H H    . ALA A 1 181 ? 5.39800  21.07200 7.61100   1.000 13.60000 ? 185 ALA A H    1 
ATOM   2684 H HA   . ALA A 1 181 ? 5.70400  23.56100 8.36600   1.000 14.87000 ? 185 ALA A HA   1 
ATOM   2685 H HB1  . ALA A 1 181 ? 4.56900  22.93300 10.31300  1.000 14.48000 ? 185 ALA A HB1  1 
ATOM   2686 H HB2  . ALA A 1 181 ? 3.82500  22.36000 9.03200   1.000 14.48000 ? 185 ALA A HB2  1 
ATOM   2687 H HB3  . ALA A 1 181 ? 4.73800  21.40500 9.91400   1.000 14.48000 ? 185 ALA A HB3  1 
ATOM   2688 N N    . VAL A 1 182 ? 7.73900  21.50800 9.71500   1.000 11.89353 ? 186 VAL A N    1 
ATOM   2689 C CA   . VAL A 1 182 ? 9.01500  21.45200 10.41900  1.000 11.35399 ? 186 VAL A CA   1 
ATOM   2690 C C    . VAL A 1 182 ? 10.03800 22.34000 9.73800   1.000 11.82773 ? 186 VAL A C    1 
ATOM   2691 O O    . VAL A 1 182 ? 10.71800 23.12600 10.39300  1.000 11.86458 ? 186 VAL A O    1 
ATOM   2692 C CB   . VAL A 1 182 ? 9.47800  19.99200 10.55000  1.000 11.64087 ? 186 VAL A CB   1 
ATOM   2693 C CG1  . VAL A 1 182 ? 10.92400 19.91700 11.03000  1.000 11.88300 ? 186 VAL A CG1  1 
ATOM   2694 C CG2  . VAL A 1 182 ? 8.57100  19.23500 11.51700  1.000 11.54349 ? 186 VAL A CG2  1 
ATOM   2695 H H    . VAL A 1 182 ? 7.45600  20.74800 9.42800   1.000 14.28000 ? 186 VAL A H    1 
ATOM   2696 H HA   . VAL A 1 182 ? 8.90100  21.80100 11.31700  1.000 13.63000 ? 186 VAL A HA   1 
ATOM   2697 H HB   . VAL A 1 182 ? 9.42600  19.57600 9.67600   1.000 13.98000 ? 186 VAL A HB   1 
ATOM   2698 H HG11 . VAL A 1 182 ? 11.13800 18.99500 11.24400  1.000 14.27000 ? 186 VAL A HG11 1 
ATOM   2699 H HG12 . VAL A 1 182 ? 11.50800 20.23600 10.32400  1.000 14.27000 ? 186 VAL A HG12 1 
ATOM   2700 H HG13 . VAL A 1 182 ? 11.02500 20.47200 11.81900  1.000 14.27000 ? 186 VAL A HG13 1 
ATOM   2701 H HG21 . VAL A 1 182 ? 8.84600  18.30500 11.54500  1.000 13.86000 ? 186 VAL A HG21 1 
ATOM   2702 H HG22 . VAL A 1 182 ? 8.65000  19.62900 12.40000  1.000 13.86000 ? 186 VAL A HG22 1 
ATOM   2703 H HG23 . VAL A 1 182 ? 7.65400  19.30000 11.20700  1.000 13.86000 ? 186 VAL A HG23 1 
ATOM   2704 N N    . THR A 1 183 ? 10.15900 22.22600 8.41500   1.000 12.24884 ? 187 THR A N    1 
ATOM   2705 C CA   . THR A 1 183 ? 11.11700 23.04500 7.68400   1.000 12.21989 ? 187 THR A CA   1 
ATOM   2706 C C    . THR A 1 183 ? 10.76300 24.52100 7.77100   1.000 11.93301 ? 187 THR A C    1 
ATOM   2707 O O    . THR A 1 183 ? 11.63500 25.37500 7.97400   1.000 12.29621 ? 187 THR A O    1 
ATOM   2708 C CB   . THR A 1 183 ? 11.18900 22.57900 6.23500   1.000 13.03051 ? 187 THR A CB   1 
ATOM   2709 O OG1  . THR A 1 183 ? 11.70500 21.24600 6.20900   1.000 14.37804 ? 187 THR A OG1  1 
ATOM   2710 C CG2  . THR A 1 183 ? 12.07300 23.47900 5.40800   1.000 15.02285 ? 187 THR A CG2  1 
ATOM   2711 H H    . THR A 1 183 ? 9.70300  21.68800 7.92400   1.000 14.71000 ? 187 THR A H    1 
ATOM   2712 H HA   . THR A 1 183 ? 11.99600 22.93400 8.07800   1.000 14.67000 ? 187 THR A HA   1 
ATOM   2713 H HB   . THR A 1 183 ? 10.30300 22.60500 5.84100   1.000 15.64000 ? 187 THR A HB   1 
ATOM   2714 H HG1  . THR A 1 183 ? 11.75100 20.97000 5.41600   1.000 17.26000 ? 187 THR A HG1  1 
ATOM   2715 H HG21 . THR A 1 183 ? 12.01300 23.23400 4.47100   1.000 18.04000 ? 187 THR A HG21 1 
ATOM   2716 H HG22 . THR A 1 183 ? 11.79500 24.40200 5.51000   1.000 18.04000 ? 187 THR A HG22 1 
ATOM   2717 H HG23 . THR A 1 183 ? 12.99600 23.39400 5.69600   1.000 18.04000 ? 187 THR A HG23 1 
ATOM   2718 N N    . GLU A 1 184 ? 9.48000  24.84700 7.56000   1.000 11.40926 ? 188 GLU A N    1 
ATOM   2719 C CA   . GLU A 1 184 ? 9.06600  26.23700 7.61400   1.000 12.98577 ? 188 GLU A CA   1 
ATOM   2720 C C    . GLU A 1 184 ? 9.38200  26.83800 8.98300   1.000 12.88839 ? 188 GLU A C    1 
ATOM   2721 O O    . GLU A 1 184 ? 9.86700  27.97000 9.07800   1.000 13.25159 ? 188 GLU A O    1 
ATOM   2722 C CB   . GLU A 1 184 ? 7.58000  26.34700 7.25200   1.000 13.57268 ? 188 GLU A CB   1 
ATOM   2723 C CG   . GLU A 1 184 ? 7.36500  26.12900 5.76700   1.000 14.35698 ? 188 GLU A CG   1 
ATOM   2724 C CD   . GLU A 1 184 ? 5.93000  25.99100 5.34400   1.000 15.42817 ? 188 GLU A CD   1 
ATOM   2725 O OE1  . GLU A 1 184 ? 5.08500  25.70400 6.19400   1.000 16.15194 ? 188 GLU A OE1  1 
ATOM   2726 O OE2  . GLU A 1 184 ? 5.66100  26.14300 4.12900   1.000 16.49145 ? 188 GLU A OE2  1 
ATOM   2727 H H    . GLU A 1 184 ? 8.85000  24.28800 7.38900   1.000 13.70000 ? 188 GLU A H    1 
ATOM   2728 H HA   . GLU A 1 184 ? 9.55200  26.75900 6.95600   1.000 15.59000 ? 188 GLU A HA   1 
ATOM   2729 H HB2  . GLU A 1 184 ? 7.07900  25.67400 7.73800   1.000 16.29000 ? 188 GLU A HB2  1 
ATOM   2730 H HB3  . GLU A 1 184 ? 7.25700  27.23200 7.48300   1.000 16.29000 ? 188 GLU A HB3  1 
ATOM   2731 H HG2  . GLU A 1 184 ? 7.73700  26.88600 5.28800   1.000 17.24000 ? 188 GLU A HG2  1 
ATOM   2732 H HG3  . GLU A 1 184 ? 7.82400  25.31400 5.50700   1.000 17.24000 ? 188 GLU A HG3  1 
ATOM   2733 N N    . SER A 1 185 ? 9.08800  26.10100 10.05000  1.000 12.33569 ? 189 SER A N    1 
ATOM   2734 C CA   . SER A 1 185 ? 9.35000  26.62700 11.38600  1.000 12.23041 ? 189 SER A CA   1 
ATOM   2735 C C    . SER A 1 185 ? 10.83700 26.69500 11.67700  1.000 12.43570 ? 189 SER A C    1 
ATOM   2736 O O    . SER A 1 185 ? 11.30700 27.66700 12.27800  1.000 12.71468 ? 189 SER A O    1 
ATOM   2737 C CB   . SER A 1 185 ? 8.63600  25.77200 12.42600  1.000 12.43044 ? 189 SER A CB   1 
ATOM   2738 O OG   . SER A 1 185 ? 7.24400  26.03100 12.33500  1.000 13.60953 ? 189 SER A OG   1 
ATOM   2739 H H    . SER A 1 185 ? 8.74400  25.31300 10.03000  1.000 14.81000 ? 189 SER A H    1 
ATOM   2740 H HA   . SER A 1 185 ? 8.99800  27.52900 11.44200  1.000 14.68000 ? 189 SER A HA   1 
ATOM   2741 H HB2  . SER A 1 185 ? 8.80500  24.83400 12.24800  1.000 14.92000 ? 189 SER A HB2  1 
ATOM   2742 H HB3  . SER A 1 185 ? 8.95300  26.00500 13.31200  1.000 14.92000 ? 189 SER A HB3  1 
ATOM   2743 H HG   . SER A 1 185 ? 6.82600  25.54500 12.87700  1.000 16.34000 ? 189 SER A HG   1 
ATOM   2744 N N    . LEU A 1 186 ? 11.59100 25.68700 11.24000  1.000 12.39622 ? 190 LEU A N    1 
ATOM   2745 C CA   . LEU A 1 186 ? 13.02900 25.73700 11.42800  1.000 11.97775 ? 190 LEU A CA   1 
ATOM   2746 C C    . LEU A 1 186 ? 13.63300 26.95100 10.72700  1.000 12.29621 ? 190 LEU A C    1 
ATOM   2747 O O    . LEU A 1 186 ? 14.49800 27.62600 11.28800  1.000 13.16210 ? 190 LEU A O    1 
ATOM   2748 C CB   . LEU A 1 186 ? 13.64600 24.43900 10.93900  1.000 12.35938 ? 190 LEU A CB   1 
ATOM   2749 C CG   . LEU A 1 186 ? 15.13000 24.29100 11.23000  1.000 12.65415 ? 190 LEU A CG   1 
ATOM   2750 C CD1  . LEU A 1 186 ? 15.40600 24.25100 12.72500  1.000 13.84377 ? 190 LEU A CD1  1 
ATOM   2751 C CD2  . LEU A 1 186 ? 15.61700 23.01000 10.58700  1.000 13.28317 ? 190 LEU A CD2  1 
ATOM   2752 H H    . LEU A 1 186 ? 11.29800 24.98200 10.84300  1.000 14.88000 ? 190 LEU A H    1 
ATOM   2753 H HA   . LEU A 1 186 ? 13.23500 25.82300 12.37200  1.000 14.38000 ? 190 LEU A HA   1 
ATOM   2754 H HB2  . LEU A 1 186 ? 13.18800 23.70000 11.36900  1.000 14.84000 ? 190 LEU A HB2  1 
ATOM   2755 H HB3  . LEU A 1 186 ? 13.53000 24.38600 9.97700   1.000 14.84000 ? 190 LEU A HB3  1 
ATOM   2756 H HG   . LEU A 1 186 ? 15.60700 25.05600 10.87100  1.000 15.19000 ? 190 LEU A HG   1 
ATOM   2757 H HD11 . LEU A 1 186 ? 16.32700 23.98600 12.86900  1.000 16.62000 ? 190 LEU A HD11 1 
ATOM   2758 H HD12 . LEU A 1 186 ? 15.25400 25.13400 13.09700  1.000 16.62000 ? 190 LEU A HD12 1 
ATOM   2759 H HD13 . LEU A 1 186 ? 14.80800 23.61000 13.13900  1.000 16.62000 ? 190 LEU A HD13 1 
ATOM   2760 H HD21 . LEU A 1 186 ? 16.55900 22.89500 10.78600  1.000 15.95000 ? 190 LEU A HD21 1 
ATOM   2761 H HD22 . LEU A 1 186 ? 15.10900 22.26400 10.94400  1.000 15.95000 ? 190 LEU A HD22 1 
ATOM   2762 H HD23 . LEU A 1 186 ? 15.48700 23.06900 9.62700   1.000 15.95000 ? 190 LEU A HD23 1 
ATOM   2763 N N    A GLN A 1 187 ? 13.17900 27.24700 9.50400   0.390 13.22001 ? 191 GLN A N    1 
ATOM   2764 N N    C GLN A 1 187 ? 13.18400 27.25400 9.50400   0.610 12.76732 ? 191 GLN A N    1 
ATOM   2765 C CA   A GLN A 1 187 ? 13.67100 28.42600 8.80000   0.390 13.97799 ? 191 GLN A CA   1 
ATOM   2766 C CA   C GLN A 1 187 ? 13.69900 28.43000 8.81300   0.610 13.03841 ? 191 GLN A CA   1 
ATOM   2767 C C    A GLN A 1 187 ? 13.38300 29.69600 9.59100   0.390 13.79639 ? 191 GLN A C    1 
ATOM   2768 C C    C GLN A 1 187 ? 13.38300 29.71100 9.57500   0.610 13.28054 ? 191 GLN A C    1 
ATOM   2769 O O    A GLN A 1 187 ? 14.25900 30.55300 9.75100   0.390 13.97799 ? 191 GLN A O    1 
ATOM   2770 O O    C GLN A 1 187 ? 14.23800 30.59500 9.69400   0.610 13.65953 ? 191 GLN A O    1 
ATOM   2771 C CB   A GLN A 1 187 ? 13.03300 28.51000 7.41100   0.390 14.98601 ? 191 GLN A CB   1 
ATOM   2772 C CB   C GLN A 1 187 ? 13.11300 28.49900 7.40300   0.610 13.39634 ? 191 GLN A CB   1 
ATOM   2773 C CG   A GLN A 1 187 ? 13.44200 29.76000 6.63000   0.390 16.53356 ? 191 GLN A CG   1 
ATOM   2774 C CG   C GLN A 1 187 ? 13.66400 29.65100 6.55300   0.610 14.04379 ? 191 GLN A CG   1 
ATOM   2775 C CD   A GLN A 1 187 ? 12.65700 29.95300 5.33800   0.390 18.53380 ? 191 GLN A CD   1 
ATOM   2776 C CD   C GLN A 1 187 ? 13.01000 30.99400 6.84200   0.610 15.49133 ? 191 GLN A CD   1 
ATOM   2777 O OE1  A GLN A 1 187 ? 11.53700 29.45800 5.19100   0.390 20.10241 ? 191 GLN A OE1  1 
ATOM   2778 O OE1  C GLN A 1 187 ? 11.85300 31.05700 7.28000   0.610 17.22049 ? 191 GLN A OE1  1 
ATOM   2779 N NE2  A GLN A 1 187 ? 13.24200 30.68800 4.39900   0.390 19.27863 ? 191 GLN A NE2  1 
ATOM   2780 N NE2  C GLN A 1 187 ? 13.74400 32.07900 6.60100   0.610 17.17574 ? 191 GLN A NE2  1 
ATOM   2781 H H    A GLN A 1 187 ? 12.59500 26.78800 9.07100   0.390 15.87000 ? 191 GLN A H    1 
ATOM   2782 H H    C GLN A 1 187 ? 12.59600 26.80500 9.06700   0.610 15.33000 ? 191 GLN A H    1 
ATOM   2783 H HA   A GLN A 1 187 ? 14.63200 28.34400 8.69100   0.390 16.78000 ? 191 GLN A HA   1 
ATOM   2784 H HA   C GLN A 1 187 ? 14.66400 28.35100 8.74500   0.610 15.65000 ? 191 GLN A HA   1 
ATOM   2785 H HB2  A GLN A 1 187 ? 13.30300 27.73500 6.89500   0.390 17.99000 ? 191 GLN A HB2  1 
ATOM   2786 H HB2  C GLN A 1 187 ? 13.31300 27.67000 6.94200   0.610 16.08000 ? 191 GLN A HB2  1 
ATOM   2787 H HB3  A GLN A 1 187 ? 12.06800 28.52300 7.51100   0.390 17.99000 ? 191 GLN A HB3  1 
ATOM   2788 H HB3  C GLN A 1 187 ? 12.15200 28.61700 7.47100   0.610 16.08000 ? 191 GLN A HB3  1 
ATOM   2789 H HG2  A GLN A 1 187 ? 13.29200 30.54000 7.18700   0.390 19.85000 ? 191 GLN A HG2  1 
ATOM   2790 H HG2  C GLN A 1 187 ? 14.61400 29.74000 6.72800   0.610 16.86000 ? 191 GLN A HG2  1 
ATOM   2791 H HG3  A GLN A 1 187 ? 14.38100 29.69200 6.39900   0.390 19.85000 ? 191 GLN A HG3  1 
ATOM   2792 H HG3  C GLN A 1 187 ? 13.51700 29.44600 5.61700   0.610 16.86000 ? 191 GLN A HG3  1 
ATOM   2793 H HE21 A GLN A 1 187 ? 14.02100 31.02400 4.53900   0.390 23.14000 ? 191 GLN A HE21 1 
ATOM   2794 H HE21 C GLN A 1 187 ? 14.54500 31.99800 6.29700   0.610 20.62000 ? 191 GLN A HE21 1 
ATOM   2795 H HE22 A GLN A 1 187 ? 12.84200 30.82700 3.65000   0.390 23.14000 ? 191 GLN A HE22 1 
ATOM   2796 H HE22 C GLN A 1 187 ? 13.41800 32.86100 6.74800   0.610 20.62000 ? 191 GLN A HE22 1 
ATOM   2797 N N    . LYS A 1 188 ? 12.14500 29.84800 10.07300  1.000 13.62532 ? 192 LYS A N    1 
ATOM   2798 C CA   . LYS A 1 188 ? 11.78600 31.05800 10.80100  1.000 13.64111 ? 192 LYS A CA   1 
ATOM   2799 C C    . LYS A 1 188 ? 12.68400 31.24600 12.02200  1.000 14.07800 ? 192 LYS A C    1 
ATOM   2800 O O    . LYS A 1 188 ? 13.06300 32.37500 12.35200  1.000 15.13339 ? 192 LYS A O    1 
ATOM   2801 C CB   . LYS A 1 188 ? 10.33300 30.98400 11.25700  1.000 15.04128 ? 192 LYS A CB   1 
ATOM   2802 C CG   . LYS A 1 188 ? 9.31500  31.03900 10.13500  1.000 15.53607 ? 192 LYS A CG   1 
ATOM   2803 C CD   . LYS A 1 188 ? 7.94500  30.60100 10.62500  1.000 15.57029 ? 192 LYS A CD   1 
ATOM   2804 C CE   . LYS A 1 188 ? 6.87000  30.72300 9.54600   1.000 16.59146 ? 192 LYS A CE   1 
ATOM   2805 N NZ   . LYS A 1 188 ? 5.54900  30.25500 10.01700  1.000 17.21785 ? 192 LYS A NZ   1 
ATOM   2806 H H    A LYS A 1 188 ? 11.51000 29.27400 9.99200   0.390 16.36000 ? 192 LYS A H    1 
ATOM   2807 H H    C LYS A 1 188 ? 11.51600 29.26600 10.00200  0.610 16.36000 ? 192 LYS A H    1 
ATOM   2808 H HA   . LYS A 1 188 ? 11.89100 31.81700 10.20700  1.000 16.37000 ? 192 LYS A HA   1 
ATOM   2809 H HB2  . LYS A 1 188 ? 10.20000 30.14700 11.73100  1.000 18.06000 ? 192 LYS A HB2  1 
ATOM   2810 H HB3  . LYS A 1 188 ? 10.15700 31.73200 11.84900  1.000 18.06000 ? 192 LYS A HB3  1 
ATOM   2811 H HG2  . LYS A 1 188 ? 9.24700  31.94900 9.80500   1.000 18.65000 ? 192 LYS A HG2  1 
ATOM   2812 H HG3  . LYS A 1 188 ? 9.59000  30.44600 9.41900   1.000 18.65000 ? 192 LYS A HG3  1 
ATOM   2813 H HD2  . LYS A 1 188 ? 7.98900  29.67200 10.90100  1.000 18.69000 ? 192 LYS A HD2  1 
ATOM   2814 H HD3  . LYS A 1 188 ? 7.68300  31.15800 11.37500  1.000 18.69000 ? 192 LYS A HD3  1 
ATOM   2815 H HE2  . LYS A 1 188 ? 6.78500  31.65300 9.28500   1.000 19.92000 ? 192 LYS A HE2  1 
ATOM   2816 H HE3  . LYS A 1 188 ? 7.12500  30.18500 8.78000   1.000 19.92000 ? 192 LYS A HE3  1 
ATOM   2817 H HZ1  . LYS A 1 188 ? 4.95100  30.32200 9.36100   1.000 20.67000 ? 192 LYS A HZ1  1 
ATOM   2818 H HZ2  . LYS A 1 188 ? 5.60100  29.40400 10.27400  1.000 20.67000 ? 192 LYS A HZ2  1 
ATOM   2819 H HZ3  . LYS A 1 188 ? 5.27900  30.74900 10.70600  1.000 20.67000 ? 192 LYS A HZ3  1 
ATOM   2820 N N    . LEU A 1 189 ? 13.00500 30.14600 12.71700  1.000 13.64111 ? 193 LEU A N    1 
ATOM   2821 C CA   . LEU A 1 189 ? 13.72300 30.22200 13.98400  1.000 14.22276 ? 193 LEU A CA   1 
ATOM   2822 C C    . LEU A 1 189 ? 15.23100 30.37700 13.79700  1.000 13.91219 ? 193 LEU A C    1 
ATOM   2823 O O    . LEU A 1 189 ? 15.88600 30.99700 14.64200  1.000 16.72569 ? 193 LEU A O    1 
ATOM   2824 C CB   . LEU A 1 189 ? 13.43600 28.96100 14.79100  1.000 13.59637 ? 193 LEU A CB   1 
ATOM   2825 C CG   . LEU A 1 189 ? 12.00000 28.83200 15.28800  1.000 13.98062 ? 193 LEU A CG   1 
ATOM   2826 C CD1  . LEU A 1 189 ? 11.66800 27.43000 15.71900  1.000 14.44647 ? 193 LEU A CD1  1 
ATOM   2827 C CD2  . LEU A 1 189 ? 11.78700 29.83100 16.45000  1.000 15.37816 ? 193 LEU A CD2  1 
ATOM   2828 H H    . LEU A 1 189 ? 12.81700 29.34400 12.47100  1.000 16.38000 ? 193 LEU A H    1 
ATOM   2829 H HA   . LEU A 1 189 ? 13.40900 30.99600 14.47700  1.000 17.07000 ? 193 LEU A HA   1 
ATOM   2830 H HB2  . LEU A 1 189 ? 13.62300 28.19000 14.23300  1.000 16.33000 ? 193 LEU A HB2  1 
ATOM   2831 H HB3  . LEU A 1 189 ? 14.01600 28.95500 15.56900  1.000 16.33000 ? 193 LEU A HB3  1 
ATOM   2832 H HG   . LEU A 1 189 ? 11.39100 29.03800 14.56100  1.000 16.79000 ? 193 LEU A HG   1 
ATOM   2833 H HD11 . LEU A 1 189 ? 10.74600 27.40100 16.01800  1.000 17.35000 ? 193 LEU A HD11 1 
ATOM   2834 H HD12 . LEU A 1 189 ? 11.79100 26.83100 14.96500  1.000 17.35000 ? 193 LEU A HD12 1 
ATOM   2835 H HD13 . LEU A 1 189 ? 12.26000 27.17400 16.44400  1.000 17.35000 ? 193 LEU A HD13 1 
ATOM   2836 H HD21 . LEU A 1 189 ? 10.91600 29.67300 16.84700  1.000 18.46000 ? 193 LEU A HD21 1 
ATOM   2837 H HD22 . LEU A 1 189 ? 12.48200 29.69700 17.11300  1.000 18.46000 ? 193 LEU A HD22 1 
ATOM   2838 H HD23 . LEU A 1 189 ? 11.83200 30.73500 16.10100  1.000 18.46000 ? 193 LEU A HD23 1 
ATOM   2839 N N    . THR A 1 190 ? 15.81700 29.77400 12.75600  1.000 13.97010 ? 194 THR A N    1 
ATOM   2840 C CA   . THR A 1 190 ? 17.26900 29.83000 12.55400  1.000 14.34383 ? 194 THR A CA   1 
ATOM   2841 C C    . THR A 1 190 ? 17.71900 30.94300 11.61900  1.000 15.68872 ? 194 THR A C    1 
ATOM   2842 O O    . THR A 1 190 ? 18.86800 31.38100 11.72200  1.000 17.67844 ? 194 THR A O    1 
ATOM   2843 C CB   . THR A 1 190 ? 17.81400 28.50500 11.98900  1.000 14.04379 ? 194 THR A CB   1 
ATOM   2844 O OG1  . THR A 1 190 ? 17.18200 28.22600 10.72100  1.000 14.60701 ? 194 THR A OG1  1 
ATOM   2845 C CG2  . THR A 1 190 ? 17.63400 27.34600 12.95600  1.000 14.58070 ? 194 THR A CG2  1 
ATOM   2846 H H    . THR A 1 190 ? 15.39600 29.32800 12.15400  1.000 16.77000 ? 194 THR A H    1 
ATOM   2847 H HA   . THR A 1 190 ? 17.66600 29.97300 13.42700  1.000 17.22000 ? 194 THR A HA   1 
ATOM   2848 H HB   . THR A 1 190 ? 18.77100 28.59100 11.85400  1.000 16.86000 ? 194 THR A HB   1 
ATOM   2849 H HG1  . THR A 1 190 ? 16.35500 28.13000 10.82700  1.000 17.53000 ? 194 THR A HG1  1 
ATOM   2850 H HG21 . THR A 1 190 ? 17.97800 26.52900 12.56200  1.000 17.50000 ? 194 THR A HG21 1 
ATOM   2851 H HG22 . THR A 1 190 ? 18.11200 27.52400 13.78100  1.000 17.50000 ? 194 THR A HG22 1 
ATOM   2852 H HG23 . THR A 1 190 ? 16.69200 27.22600 13.15800  1.000 17.50000 ? 194 THR A HG23 1 
ATOM   2853 N N    . LEU A 1 191 ? 16.86300 31.38800 10.69500  1.000 15.19393 ? 195 LEU A N    1 
ATOM   2854 C CA   . LEU A 1 191 ? 17.26600 32.31500 9.64500   1.000 16.86518 ? 195 LEU A CA   1 
ATOM   2855 C C    . LEU A 1 191 ? 16.33000 33.51300 9.54900   1.000 17.96531 ? 195 LEU A C    1 
ATOM   2856 O O    . LEU A 1 191 ? 16.72800 34.59000 9.10400   1.000 19.31021 ? 195 LEU A O    1 
ATOM   2857 C CB   . LEU A 1 191 ? 17.29300 31.58100 8.30000   1.000 16.69411 ? 195 LEU A CB   1 
ATOM   2858 C CG   . LEU A 1 191 ? 18.25600 30.40000 8.17500   1.000 16.69937 ? 195 LEU A CG   1 
ATOM   2859 C CD1  . LEU A 1 191 ? 18.03000 29.65800 6.88600   1.000 17.64685 ? 195 LEU A CD1  1 
ATOM   2860 C CD2  . LEU A 1 191 ? 19.69500 30.87900 8.28600   1.000 17.35208 ? 195 LEU A CD2  1 
ATOM   2861 H H    . LEU A 1 191 ? 16.03400 31.16400 10.65700  1.000 18.24000 ? 195 LEU A H    1 
ATOM   2862 H HA   . LEU A 1 191 ? 18.15100 32.65200 9.85400   1.000 20.25000 ? 195 LEU A HA   1 
ATOM   2863 H HB2  . LEU A 1 191 ? 16.40200 31.23900 8.12800   1.000 20.04000 ? 195 LEU A HB2  1 
ATOM   2864 H HB3  . LEU A 1 191 ? 17.54100 32.22100 7.61500   1.000 20.04000 ? 195 LEU A HB3  1 
ATOM   2865 H HG   . LEU A 1 191 ? 18.09000 29.77800 8.90000   1.000 20.05000 ? 195 LEU A HG   1 
ATOM   2866 H HD11 . LEU A 1 191 ? 18.65900 28.92100 6.83200   1.000 21.18000 ? 195 LEU A HD11 1 
ATOM   2867 H HD12 . LEU A 1 191 ? 17.12100 29.31900 6.87200   1.000 21.18000 ? 195 LEU A HD12 1 
ATOM   2868 H HD13 . LEU A 1 191 ? 18.16800 30.26600 6.14300   1.000 21.18000 ? 195 LEU A HD13 1 
ATOM   2869 H HD21 . LEU A 1 191 ? 20.29100 30.13600 8.09800   1.000 20.83000 ? 195 LEU A HD21 1 
ATOM   2870 H HD22 . LEU A 1 191 ? 19.84200 31.59100 7.64400   1.000 20.83000 ? 195 LEU A HD22 1 
ATOM   2871 H HD23 . LEU A 1 191 ? 19.85000 31.20800 9.18500   1.000 20.83000 ? 195 LEU A HD23 1 
ATOM   2872 N N    . GLY A 1 192 ? 15.07000 33.32400 9.94400   1.000 17.21259 ? 196 GLY A N    1 
ATOM   2873 C CA   . GLY A 1 192 ? 14.07500 34.37500 9.93600   1.000 18.86279 ? 196 GLY A CA   1 
ATOM   2874 C C    . GLY A 1 192 ? 14.10500 35.19600 11.20600  1.000 20.14978 ? 196 GLY A C    1 
ATOM   2875 O O    . GLY A 1 192 ? 15.11600 35.26300 11.90400  1.000 20.68143 ? 196 GLY A O    1 
ATOM   2876 H H    . GLY A 1 192 ? 14.76700 32.57100 10.22800  1.000 20.66000 ? 196 GLY A H    1 
ATOM   2877 H HA2  . GLY A 1 192 ? 14.23800 34.96700 9.18500   1.000 22.64000 ? 196 GLY A HA2  1 
ATOM   2878 H HA3  . GLY A 1 192 ? 13.19300 33.98300 9.84500   1.000 22.64000 ? 196 GLY A HA3  1 
ATOM   2879 N N    . SER A 1 193 ? 12.95800 35.80200 11.52900  1.000 20.46035 ? 197 SER A N    1 
ATOM   2880 C CA   . SER A 1 193 ? 12.85800 36.78100 12.60400  1.000 21.64996 ? 197 SER A CA   1 
ATOM   2881 C C    . SER A 1 193 ? 12.09300 36.27600 13.82200  1.000 20.22874 ? 197 SER A C    1 
ATOM   2882 O O    . SER A 1 193 ? 11.78200 37.06900 14.71300  1.000 21.54995 ? 197 SER A O    1 
ATOM   2883 C CB   . SER A 1 193 ? 12.21100 38.06300 12.08000  1.000 24.66348 ? 197 SER A CB   1 
ATOM   2884 O OG   . SER A 1 193 ? 10.86500 37.82500 11.70600  1.000 27.72438 ? 197 SER A OG   1 
ATOM   2885 H H    . SER A 1 193 ? 12.21000 35.65700 11.12900  1.000 24.56000 ? 197 SER A H    1 
ATOM   2886 H HA   . SER A 1 193 ? 13.75800 36.98600 12.90200  1.000 25.99000 ? 197 SER A HA   1 
ATOM   2887 H HB2  . SER A 1 193 ? 12.23100 38.73600 12.77700  1.000 29.60000 ? 197 SER A HB2  1 
ATOM   2888 H HB3  . SER A 1 193 ? 12.70500 38.37300 11.30500  1.000 29.60000 ? 197 SER A HB3  1 
ATOM   2889 H HG   . SER A 1 193 ? 10.82700 37.18600 11.16200  1.000 33.28000 ? 197 SER A HG   1 
ATOM   2890 N N    . ALA A 1 194 ? 11.81100 34.97900 13.90200  1.000 18.93648 ? 198 ALA A N    1 
ATOM   2891 C CA   . ALA A 1 194 ? 11.01600 34.46700 15.01800  1.000 18.71540 ? 198 ALA A CA   1 
ATOM   2892 C C    . ALA A 1 194 ? 11.73000 34.62800 16.35200  1.000 19.82869 ? 198 ALA A C    1 
ATOM   2893 O O    . ALA A 1 194 ? 11.07300 34.84100 17.37500  1.000 20.98673 ? 198 ALA A O    1 
ATOM   2894 C CB   . ALA A 1 194 ? 10.64000 33.00900 14.76400  1.000 18.24166 ? 198 ALA A CB   1 
ATOM   2895 H H    . ALA A 1 194 ? 12.06200 34.38300 13.33500  1.000 22.73000 ? 198 ALA A H    1 
ATOM   2896 H HA   . ALA A 1 194 ? 10.19200 34.97600 15.07500  1.000 22.47000 ? 198 ALA A HA   1 
ATOM   2897 H HB1  . ALA A 1 194 ? 10.12300 32.68000 15.51600  1.000 21.90000 ? 198 ALA A HB1  1 
ATOM   2898 H HB2  . ALA A 1 194 ? 10.11300 32.95600 13.95100  1.000 21.90000 ? 198 ALA A HB2  1 
ATOM   2899 H HB3  . ALA A 1 194 ? 11.45100 32.48600 14.66700  1.000 21.90000 ? 198 ALA A HB3  1 
ATOM   2900 N N    . LEU A 1 195 ? 13.05500 34.52600 16.36100  1.000 19.07334 ? 199 LEU A N    1 
ATOM   2901 C CA   . LEU A 1 195 ? 13.87500 34.81400 17.52600  1.000 20.15242 ? 199 LEU A CA   1 
ATOM   2902 C C    . LEU A 1 195 ? 14.69600 36.07300 17.28300  1.000 21.51311 ? 199 LEU A C    1 
ATOM   2903 O O    . LEU A 1 195 ? 15.07100 36.37900 16.15000  1.000 22.16845 ? 199 LEU A O    1 
ATOM   2904 C CB   . LEU A 1 195 ? 14.84900 33.66900 17.81400  1.000 19.61551 ? 199 LEU A CB   1 
ATOM   2905 C CG   . LEU A 1 195 ? 14.26000 32.30600 18.15700  1.000 19.15493 ? 199 LEU A CG   1 
ATOM   2906 C CD1  . LEU A 1 195 ? 15.36600 31.27900 18.24800  1.000 19.15230 ? 199 LEU A CD1  1 
ATOM   2907 C CD2  . LEU A 1 195 ? 13.47000 32.38800 19.44500  1.000 20.37350 ? 199 LEU A CD2  1 
ATOM   2908 H H    . LEU A 1 195 ? 13.51700 34.28100 15.67800  1.000 22.90000 ? 199 LEU A H    1 
ATOM   2909 H HA   . LEU A 1 195 ? 13.29400 34.94400 18.29200  1.000 24.19000 ? 199 LEU A HA   1 
ATOM   2910 H HB2  . LEU A 1 195 ? 15.40100 33.54500 17.02600  1.000 23.55000 ? 199 LEU A HB2  1 
ATOM   2911 H HB3  . LEU A 1 195 ? 15.40100 33.93300 18.56700  1.000 23.55000 ? 199 LEU A HB3  1 
ATOM   2912 H HG   . LEU A 1 195 ? 13.64800 32.02200 17.46000  1.000 22.99000 ? 199 LEU A HG   1 
ATOM   2913 H HD11 . LEU A 1 195 ? 14.97900 30.41500 18.46000  1.000 22.99000 ? 199 LEU A HD11 1 
ATOM   2914 H HD12 . LEU A 1 195 ? 15.82700 31.23400 17.39500  1.000 22.99000 ? 199 LEU A HD12 1 
ATOM   2915 H HD13 . LEU A 1 195 ? 15.98700 31.54400 18.94500  1.000 22.99000 ? 199 LEU A HD13 1 
ATOM   2916 H HD21 . LEU A 1 195 ? 13.20500 31.49400 19.71100  1.000 24.46000 ? 199 LEU A HD21 1 
ATOM   2917 H HD22 . LEU A 1 195 ? 14.02700 32.78600 20.13200  1.000 24.46000 ? 199 LEU A HD22 1 
ATOM   2918 H HD23 . LEU A 1 195 ? 12.68300 32.93600 19.29900  1.000 24.46000 ? 199 LEU A HD23 1 
ATOM   2919 N N    . ALA A 1 196 ? 14.98700 36.79200 18.36200  1.000 21.77103 ? 200 ALA A N    1 
ATOM   2920 C CA   . ALA A 1 196 ? 15.91700 37.90900 18.29500  1.000 23.19752 ? 200 ALA A CA   1 
ATOM   2921 C C    . ALA A 1 196 ? 17.31300 37.39700 17.94500  1.000 22.46322 ? 200 ALA A C    1 
ATOM   2922 O O    . ALA A 1 196 ? 17.65100 36.24000 18.18100  1.000 21.28939 ? 200 ALA A O    1 
ATOM   2923 C CB   . ALA A 1 196 ? 15.94700 38.63300 19.63900  1.000 24.83192 ? 200 ALA A CB   1 
ATOM   2924 H H    . ALA A 1 196 ? 14.65900 36.65200 19.14500  1.000 26.13000 ? 200 ALA A H    1 
ATOM   2925 H HA   . ALA A 1 196 ? 15.64000 38.54000 17.61300  1.000 27.84000 ? 200 ALA A HA   1 
ATOM   2926 H HB1  . ALA A 1 196 ? 16.58000 39.36600 19.58800  1.000 29.81000 ? 200 ALA A HB1  1 
ATOM   2927 H HB2  . ALA A 1 196 ? 15.06000 38.97500 19.83300  1.000 29.81000 ? 200 ALA A HB2  1 
ATOM   2928 H HB3  . ALA A 1 196 ? 16.21900 38.00700 20.32800  1.000 29.81000 ? 200 ALA A HB3  1 
ATOM   2929 N N    . ALA A 1 197 ? 18.13900 38.28000 17.38700  1.000 23.34754 ? 201 ALA A N    1 
ATOM   2930 C CA   . ALA A 1 197 ? 19.40400 37.83800 16.79700  1.000 23.97656 ? 201 ALA A CA   1 
ATOM   2931 C C    . ALA A 1 197 ? 20.29100 37.05000 17.75600  1.000 23.74232 ? 201 ALA A C    1 
ATOM   2932 O O    . ALA A 1 197 ? 20.83200 36.01100 17.34700  1.000 22.40269 ? 201 ALA A O    1 
ATOM   2933 C CB   . ALA A 1 197 ? 20.15100 39.04600 16.21100  1.000 25.80309 ? 201 ALA A CB   1 
ATOM   2934 H H    . ALA A 1 197 ? 17.99400 39.12700 17.33700  1.000 28.02000 ? 201 ALA A H    1 
ATOM   2935 H HA   . ALA A 1 197 ? 19.18100 37.24000 16.06600  1.000 28.78000 ? 201 ALA A HA   1 
ATOM   2936 H HB1  . ALA A 1 197 ? 20.98000 38.74100 15.81200  1.000 30.97000 ? 201 ALA A HB1  1 
ATOM   2937 H HB2  . ALA A 1 197 ? 19.59400 39.46500 15.53700  1.000 30.97000 ? 201 ALA A HB2  1 
ATOM   2938 H HB3  . ALA A 1 197 ? 20.33800 39.67700 16.92400  1.000 30.97000 ? 201 ALA A HB3  1 
ATOM   2939 N N    . PRO A 1 198 ? 20.50000 37.46900 19.00900  1.000 23.98709 ? 202 PRO A N    1 
ATOM   2940 C CA   . PRO A 1 198 ? 21.35500 36.65900 19.89500  1.000 23.33174 ? 202 PRO A CA   1 
ATOM   2941 C C    . PRO A 1 198 ? 20.79000 35.27500 20.15100  1.000 21.03936 ? 202 PRO A C    1 
ATOM   2942 O O    . PRO A 1 198 ? 21.53000 34.28200 20.11800  1.000 20.38139 ? 202 PRO A O    1 
ATOM   2943 C CB   . PRO A 1 198 ? 21.45100 37.50700 21.17800  1.000 24.91088 ? 202 PRO A CB   1 
ATOM   2944 C CG   . PRO A 1 198 ? 21.00100 38.88100 20.78000  1.000 26.01628 ? 202 PRO A CG   1 
ATOM   2945 C CD   . PRO A 1 198 ? 20.00300 38.68000 19.68100  1.000 25.03195 ? 202 PRO A CD   1 
ATOM   2946 H HA   . PRO A 1 198 ? 22.24400 36.57800 19.51600  1.000 28.01000 ? 202 PRO A HA   1 
ATOM   2947 H HB2  . PRO A 1 198 ? 20.87000 37.13600 21.86100  1.000 29.90000 ? 202 PRO A HB2  1 
ATOM   2948 H HB3  . PRO A 1 198 ? 22.36800 37.52100 21.49500  1.000 29.90000 ? 202 PRO A HB3  1 
ATOM   2949 H HG2  . PRO A 1 198 ? 20.59100 39.32400 21.53900  1.000 31.23000 ? 202 PRO A HG2  1 
ATOM   2950 H HG3  . PRO A 1 198 ? 21.76000 39.39600 20.46500  1.000 31.23000 ? 202 PRO A HG3  1 
ATOM   2951 H HD2  . PRO A 1 198 ? 19.11400 38.53700 20.04100  1.000 30.05000 ? 202 PRO A HD2  1 
ATOM   2952 H HD3  . PRO A 1 198 ? 19.99800 39.43700 19.07400  1.000 30.05000 ? 202 PRO A HD3  1 
ATOM   2953 N N    . GLN A 1 199 ? 19.48200 35.18900 20.40600  1.000 19.40233 ? 203 GLN A N    1 
ATOM   2954 C CA   . GLN A 1 199 ? 18.84300 33.89900 20.63100  1.000 19.51287 ? 203 GLN A CA   1 
ATOM   2955 C C    . GLN A 1 199 ? 18.86900 33.03900 19.37300  1.000 17.81529 ? 203 GLN A C    1 
ATOM   2956 O O    . GLN A 1 199 ? 19.04500 31.81500 19.45100  1.000 15.97034 ? 203 GLN A O    1 
ATOM   2957 C CB   . GLN A 1 199 ? 17.40900 34.11800 21.11800  1.000 19.22336 ? 203 GLN A CB   1 
ATOM   2958 C CG   . GLN A 1 199 ? 17.27700 34.58300 22.58800  1.000 20.52088 ? 203 GLN A CG   1 
ATOM   2959 C CD   . GLN A 1 199 ? 17.71600 36.02100 22.81600  1.000 23.01065 ? 203 GLN A CD   1 
ATOM   2960 O OE1  . GLN A 1 199 ? 17.78700 36.82400 21.88600  1.000 23.91076 ? 203 GLN A OE1  1 
ATOM   2961 N NE2  . GLN A 1 199 ? 17.99100 36.35500 24.06400  1.000 25.67939 ? 203 GLN A NE2  1 
ATOM   2962 H H    . GLN A 1 199 ? 18.94800 35.86100 20.45200  1.000 23.29000 ? 203 GLN A H    1 
ATOM   2963 H HA   . GLN A 1 199 ? 19.32700 33.41900 21.32200  1.000 23.42000 ? 203 GLN A HA   1 
ATOM   2964 H HB2  . GLN A 1 199 ? 16.99600 34.79600 20.56100  1.000 23.07000 ? 203 GLN A HB2  1 
ATOM   2965 H HB3  . GLN A 1 199 ? 16.92600 33.28000 21.03500  1.000 23.07000 ? 203 GLN A HB3  1 
ATOM   2966 H HG2  . GLN A 1 199 ? 16.34800 34.51100 22.85600  1.000 24.64000 ? 203 GLN A HG2  1 
ATOM   2967 H HG3  . GLN A 1 199 ? 17.82900 34.01300 23.14700  1.000 24.64000 ? 203 GLN A HG3  1 
ATOM   2968 H HE21 . GLN A 1 199 ? 17.91800 35.77100 24.69200  1.000 30.82000 ? 203 GLN A HE21 1 
ATOM   2969 H HE22 . GLN A 1 199 ? 18.24400 37.15600 24.24900  1.000 30.82000 ? 203 GLN A HE22 1 
ATOM   2970 N N    A ARG A 1 200 ? 18.68900 33.65800 18.20500  0.670 17.67580 ? 204 ARG A N    1 
ATOM   2971 N N    B ARG A 1 200 ? 18.70800 33.66200 18.20400  0.330 17.45472 ? 204 ARG A N    1 
ATOM   2972 C CA   A ARG A 1 200 ? 18.78400 32.93100 16.94300  0.670 17.91267 ? 204 ARG A CA   1 
ATOM   2973 C CA   B ARG A 1 200 ? 18.77500 32.91500 16.95300  0.330 17.38103 ? 204 ARG A CA   1 
ATOM   2974 C C    A ARG A 1 200 ? 20.14500 32.25700 16.80600  0.670 17.09415 ? 204 ARG A C    1 
ATOM   2975 C C    B ARG A 1 200 ? 20.14200 32.25900 16.78100  0.330 17.05468 ? 204 ARG A C    1 
ATOM   2976 O O    A ARG A 1 200 ? 20.23700 31.06300 16.48500  0.670 15.46501 ? 204 ARG A O    1 
ATOM   2977 O O    B ARG A 1 200 ? 20.23600 31.08100 16.41100  0.330 16.27037 ? 204 ARG A O    1 
ATOM   2978 C CB   A ARG A 1 200 ? 18.56800 33.92500 15.80400  0.670 19.30231 ? 204 ARG A CB   1 
ATOM   2979 C CB   B ARG A 1 200 ? 18.47500 33.85200 15.78100  0.330 17.93373 ? 204 ARG A CB   1 
ATOM   2980 C CG   A ARG A 1 200 ? 18.52600 33.33500 14.40700  0.670 20.28401 ? 204 ARG A CG   1 
ATOM   2981 C CG   B ARG A 1 200 ? 18.47100 33.16900 14.42100  0.330 17.99426 ? 204 ARG A CG   1 
ATOM   2982 C CD   A ARG A 1 200 ? 18.38500 34.46900 13.39000  0.670 22.09739 ? 204 ARG A CD   1 
ATOM   2983 C CD   B ARG A 1 200 ? 18.13500 34.15400 13.30400  0.330 18.47853 ? 204 ARG A CD   1 
ATOM   2984 N NE   A ARG A 1 200 ? 17.33800 35.39700 13.81100  0.670 24.31081 ? 204 ARG A NE   1 
ATOM   2985 N NE   B ARG A 1 200 ? 19.00100 35.32900 13.32800  0.330 19.08387 ? 204 ARG A NE   1 
ATOM   2986 C CZ   A ARG A 1 200 ? 17.32600 36.70000 13.57100  0.670 25.54254 ? 204 ARG A CZ   1 
ATOM   2987 C CZ   B ARG A 1 200 ? 18.87000 36.38200 12.53200  0.330 19.99187 ? 204 ARG A CZ   1 
ATOM   2988 N NH1  A ARG A 1 200 ? 18.26100 37.28000 12.83800  0.670 26.89270 ? 204 ARG A NH1  1 
ATOM   2989 N NH1  B ARG A 1 200 ? 17.90500 36.45300 11.63000  0.330 20.46035 ? 204 ARG A NH1  1 
ATOM   2990 N NH2  A ARG A 1 200 ? 16.35800 37.44400 14.09400  0.670 26.11103 ? 204 ARG A NH2  1 
ATOM   2991 N NH2  B ARG A 1 200 ? 19.72800 37.39100 12.64600  0.330 20.39981 ? 204 ARG A NH2  1 
ATOM   2992 H H    A ARG A 1 200 ? 18.51100 34.49500 18.11700  0.670 21.22000 ? 204 ARG A H    1 
ATOM   2993 H H    B ARG A 1 200 ? 18.56100 34.50500 18.11100  0.330 20.95000 ? 204 ARG A H    1 
ATOM   2994 H HA   A ARG A 1 200 ? 18.10400 32.24000 16.90500  0.670 21.50000 ? 204 ARG A HA   1 
ATOM   2995 H HA   B ARG A 1 200 ? 18.10500 32.21300 16.96400  0.330 20.86000 ? 204 ARG A HA   1 
ATOM   2996 H HB2  A ARG A 1 200 ? 17.72200 34.37600 15.95100  0.670 23.17000 ? 204 ARG A HB2  1 
ATOM   2997 H HB2  B ARG A 1 200 ? 17.59800 34.24500 15.91500  0.330 21.53000 ? 204 ARG A HB2  1 
ATOM   2998 H HB3  A ARG A 1 200 ? 19.29400 34.56800 15.82200  0.670 23.17000 ? 204 ARG A HB3  1 
ATOM   2999 H HB3  B ARG A 1 200 ? 19.15100 34.54700 15.76000  0.330 21.53000 ? 204 ARG A HB3  1 
ATOM   3000 H HG2  A ARG A 1 200 ? 19.34700 32.85000 14.22800  0.670 24.35000 ? 204 ARG A HG2  1 
ATOM   3001 H HG2  B ARG A 1 200 ? 19.35000 32.79700 14.24500  0.330 21.60000 ? 204 ARG A HG2  1 
ATOM   3002 H HG3  A ARG A 1 200 ? 17.76400 32.74000 14.32300  0.670 24.35000 ? 204 ARG A HG3  1 
ATOM   3003 H HG3  B ARG A 1 200 ? 17.80500 32.46400 14.41600  0.330 21.60000 ? 204 ARG A HG3  1 
ATOM   3004 H HD2  A ARG A 1 200 ? 19.22200 34.95500 13.32500  0.670 26.53000 ? 204 ARG A HD2  1 
ATOM   3005 H HD2  B ARG A 1 200 ? 18.24700 33.71500 12.44600  0.330 22.18000 ? 204 ARG A HD2  1 
ATOM   3006 H HD3  A ARG A 1 200 ? 18.14600 34.10300 12.52400  0.670 26.53000 ? 204 ARG A HD3  1 
ATOM   3007 H HD3  B ARG A 1 200 ? 17.21800 34.45200 13.40700  0.330 22.18000 ? 204 ARG A HD3  1 
ATOM   3008 H HE   A ARG A 1 200 ? 16.67500 35.07000 14.25000  0.670 29.18000 ? 204 ARG A HE   1 
ATOM   3009 H HE   B ARG A 1 200 ? 19.64300 35.34000 13.90100  0.330 22.91000 ? 204 ARG A HE   1 
ATOM   3010 H HH11 A ARG A 1 200 ? 18.89900 36.80900 12.50300  0.670 32.28000 ? 204 ARG A HH11 1 
ATOM   3011 H HH11 B ARG A 1 200 ? 17.34300 35.80600 11.54900  0.330 24.56000 ? 204 ARG A HH11 1 
ATOM   3012 H HH12 A ARG A 1 200 ? 18.23300 38.12700 12.69600  0.670 32.28000 ? 204 ARG A HH12 1 
ATOM   3013 H HH12 B ARG A 1 200 ? 17.83900 37.14500 11.12400  0.330 24.56000 ? 204 ARG A HH12 1 
ATOM   3014 H HH21 A ARG A 1 200 ? 15.75100 37.07900 14.58100  0.670 31.34000 ? 204 ARG A HH21 1 
ATOM   3015 H HH21 B ARG A 1 200 ? 20.35800 37.35600 13.23000  0.330 24.49000 ? 204 ARG A HH21 1 
ATOM   3016 H HH22 A ARG A 1 200 ? 16.33900 38.29100 13.94600  0.670 31.34000 ? 204 ARG A HH22 1 
ATOM   3017 H HH22 B ARG A 1 200 ? 19.65300 38.07900 12.13500  0.330 24.49000 ? 204 ARG A HH22 1 
ATOM   3018 N N    . GLN A 1 201 ? 21.22300 33.00800 17.04400  1.000 17.33103 ? 205 GLN A N    1 
ATOM   3019 C CA   . GLN A 1 201 ? 22.55100 32.42100 16.90800  1.000 18.61539 ? 205 GLN A CA   1 
ATOM   3020 C C    . GLN A 1 201 ? 22.79900 31.33500 17.95700  1.000 16.96256 ? 205 GLN A C    1 
ATOM   3021 O O    . GLN A 1 201 ? 23.45300 30.32700 17.66300  1.000 17.25470 ? 205 GLN A O    1 
ATOM   3022 C CB   . GLN A 1 201 ? 23.62800 33.49400 16.99300  1.000 20.28138 ? 205 GLN A CB   1 
ATOM   3023 C CG   . GLN A 1 201 ? 25.01600 32.96300 16.66000  1.000 22.27372 ? 205 GLN A CG   1 
ATOM   3024 C CD   . GLN A 1 201 ? 25.11400 32.47500 15.22800  1.000 23.39491 ? 205 GLN A CD   1 
ATOM   3025 O OE1  . GLN A 1 201 ? 24.76100 33.19300 14.29700  1.000 24.23712 ? 205 GLN A OE1  1 
ATOM   3026 N NE2  . GLN A 1 201 ? 25.59200 31.24600 15.04600  1.000 22.77642 ? 205 GLN A NE2  1 
ATOM   3027 H H    A GLN A 1 201 ? 21.21000 33.83500 17.27900  0.670 20.81000 ? 205 GLN A H    1 
ATOM   3028 H H    B GLN A 1 201 ? 21.20900 33.83100 17.29500  0.330 20.81000 ? 205 GLN A H    1 
ATOM   3029 H HA   . GLN A 1 201 ? 22.61300 32.01400 16.03000  1.000 22.35000 ? 205 GLN A HA   1 
ATOM   3030 H HB2  . GLN A 1 201 ? 23.41800 34.20200 16.36400  1.000 24.34000 ? 205 GLN A HB2  1 
ATOM   3031 H HB3  . GLN A 1 201 ? 23.65100 33.84700 17.89600  1.000 24.34000 ? 205 GLN A HB3  1 
ATOM   3032 H HG2  . GLN A 1 201 ? 25.66600 33.67300 16.78200  1.000 26.74000 ? 205 GLN A HG2  1 
ATOM   3033 H HG3  . GLN A 1 201 ? 25.22200 32.21900 17.24700  1.000 26.74000 ? 205 GLN A HG3  1 
ATOM   3034 H HE21 . GLN A 1 201 ? 25.82800 30.77200 15.72300  1.000 27.34000 ? 205 GLN A HE21 1 
ATOM   3035 H HE22 . GLN A 1 201 ? 25.66600 30.92700 14.25000  1.000 27.34000 ? 205 GLN A HE22 1 
ATOM   3036 N N    . GLN A 1 202 ? 22.25800 31.49600 19.16800  1.000 16.37565 ? 206 GLN A N    1 
ATOM   3037 C CA   . GLN A 1 202 ? 22.38900 30.43900 20.16300  1.000 17.32050 ? 206 GLN A CA   1 
ATOM   3038 C C    . GLN A 1 202 ? 21.68500 29.16500 19.71300  1.000 16.23353 ? 206 GLN A C    1 
ATOM   3039 O O    . GLN A 1 202 ? 22.20200 28.05800 19.90500  1.000 16.13351 ? 206 GLN A O    1 
ATOM   3040 C CB   . GLN A 1 202 ? 21.82400 30.90400 21.50400  1.000 18.22324 ? 206 GLN A CB   1 
ATOM   3041 C CG   . GLN A 1 202 ? 21.95300 29.86000 22.61700  1.000 18.93911 ? 206 GLN A CG   1 
ATOM   3042 C CD   . GLN A 1 202 ? 23.40000 29.50100 22.93100  1.000 20.61300 ? 206 GLN A CD   1 
ATOM   3043 O OE1  . GLN A 1 202 ? 24.03900 30.14100 23.77000  1.000 22.01843 ? 206 GLN A OE1  1 
ATOM   3044 N NE2  . GLN A 1 202 ? 23.92300 28.47600 22.25100  1.000 19.67868 ? 206 GLN A NE2  1 
ATOM   3045 H H    . GLN A 1 202 ? 21.82200 32.19000 19.42900  1.000 19.66000 ? 206 GLN A H    1 
ATOM   3046 H HA   . GLN A 1 202 ? 23.33200 30.24200 20.28000  1.000 20.79000 ? 206 GLN A HA   1 
ATOM   3047 H HB2  . GLN A 1 202 ? 22.30100 31.70000 21.78500  1.000 21.87000 ? 206 GLN A HB2  1 
ATOM   3048 H HB3  . GLN A 1 202 ? 20.88100 31.10500 21.39300  1.000 21.87000 ? 206 GLN A HB3  1 
ATOM   3049 H HG2  . GLN A 1 202 ? 21.54900 30.21100 23.42600  1.000 22.73000 ? 206 GLN A HG2  1 
ATOM   3050 H HG3  . GLN A 1 202 ? 21.49700 29.04900 22.34300  1.000 22.73000 ? 206 GLN A HG3  1 
ATOM   3051 H HE21 . GLN A 1 202 ? 23.44600 28.05700 21.67000  1.000 23.62000 ? 206 GLN A HE21 1 
ATOM   3052 H HE22 . GLN A 1 202 ? 24.73600 28.23500 22.39300  1.000 23.62000 ? 206 GLN A HE22 1 
ATOM   3053 N N    . PHE A 1 203 ? 20.49300 29.29900 19.13000  1.000 15.34658 ? 207 PHE A N    1 
ATOM   3054 C CA   . PHE A 1 203 ? 19.76900 28.13200 18.62700  1.000 14.33593 ? 207 PHE A CA   1 
ATOM   3055 C C    . PHE A 1 203 ? 20.57800 27.45500 17.52700  1.000 14.52016 ? 207 PHE A C    1 
ATOM   3056 O O    . PHE A 1 203 ? 20.77400 26.23400 17.54200  1.000 14.59912 ? 207 PHE A O    1 
ATOM   3057 C CB   . PHE A 1 203 ? 18.36400 28.57000 18.15400  1.000 14.97548 ? 207 PHE A CB   1 
ATOM   3058 C CG   . PHE A 1 203 ? 17.47200 27.42600 17.72700  1.000 14.49384 ? 207 PHE A CG   1 
ATOM   3059 C CD1  . PHE A 1 203 ? 17.39200 26.26200 18.48500  1.000 15.49133 ? 207 PHE A CD1  1 
ATOM   3060 C CD2  . PHE A 1 203 ? 16.69200 27.51900 16.58200  1.000 15.03601 ? 207 PHE A CD2  1 
ATOM   3061 C CE1  . PHE A 1 203 ? 16.59200 25.20800 18.09600  1.000 15.12023 ? 207 PHE A CE1  1 
ATOM   3062 C CE2  . PHE A 1 203 ? 15.87500 26.46400 16.20300  1.000 14.51753 ? 207 PHE A CE2  1 
ATOM   3063 C CZ   . PHE A 1 203 ? 15.83200 25.30500 16.94300  1.000 14.11485 ? 207 PHE A CZ   1 
ATOM   3064 H H    . PHE A 1 203 ? 20.08600 30.04800 19.01300  1.000 18.42000 ? 207 PHE A H    1 
ATOM   3065 H HA   . PHE A 1 203 ? 19.63500 27.47700 19.33000  1.000 17.21000 ? 207 PHE A HA   1 
ATOM   3066 H HB2  . PHE A 1 203 ? 17.92100 29.03300 18.88300  1.000 17.98000 ? 207 PHE A HB2  1 
ATOM   3067 H HB3  . PHE A 1 203 ? 18.46300 29.16500 17.39500  1.000 17.98000 ? 207 PHE A HB3  1 
ATOM   3068 H HD1  . PHE A 1 203 ? 17.88800 26.19300 19.26800  1.000 18.60000 ? 207 PHE A HD1  1 
ATOM   3069 H HD2  . PHE A 1 203 ? 16.71700 28.29200 16.06600  1.000 18.05000 ? 207 PHE A HD2  1 
ATOM   3070 H HE1  . PHE A 1 203 ? 16.56300 24.43300 18.60800  1.000 18.15000 ? 207 PHE A HE1  1 
ATOM   3071 H HE2  . PHE A 1 203 ? 15.34900 26.54100 15.44000  1.000 17.43000 ? 207 PHE A HE2  1 
ATOM   3072 H HZ   . PHE A 1 203 ? 15.29900 24.59400 16.67100  1.000 16.94000 ? 207 PHE A HZ   1 
ATOM   3073 N N    . VAL A 1 204 ? 21.10200 28.25200 16.59600  1.000 14.94127 ? 208 VAL A N    1 
ATOM   3074 C CA   . VAL A 1 204 ? 21.94600 27.71400 15.53700  1.000 15.44133 ? 208 VAL A CA   1 
ATOM   3075 C C    . VAL A 1 204 ? 23.15100 26.99700 16.12600  1.000 14.60965 ? 208 VAL A C    1 
ATOM   3076 O O    . VAL A 1 204 ? 23.50000 25.88900 15.70300  1.000 15.02549 ? 208 VAL A O    1 
ATOM   3077 C CB   . VAL A 1 204 ? 22.36100 28.84700 14.58700  1.000 15.82558 ? 208 VAL A CB   1 
ATOM   3078 C CG1  . VAL A 1 204 ? 23.50900 28.41400 13.70400  1.000 16.48882 ? 208 VAL A CG1  1 
ATOM   3079 C CG2  . VAL A 1 204 ? 21.18900 29.27100 13.73400  1.000 16.06245 ? 208 VAL A CG2  1 
ATOM   3080 H H    . VAL A 1 204 ? 20.98400 29.10300 16.55700  1.000 17.94000 ? 208 VAL A H    1 
ATOM   3081 H HA   . VAL A 1 204 ? 21.44200 27.05800 15.03100  1.000 18.54000 ? 208 VAL A HA   1 
ATOM   3082 H HB   . VAL A 1 204 ? 22.65300 29.60500 15.11800  1.000 19.00000 ? 208 VAL A HB   1 
ATOM   3083 H HG11 . VAL A 1 204 ? 23.57900 29.02400 12.95300  1.000 19.79000 ? 208 VAL A HG11 1 
ATOM   3084 H HG12 . VAL A 1 204 ? 24.33000 28.43100 14.22200  1.000 19.79000 ? 208 VAL A HG12 1 
ATOM   3085 H HG13 . VAL A 1 204 ? 23.33900 27.51400 13.38400  1.000 19.79000 ? 208 VAL A HG13 1 
ATOM   3086 H HG21 . VAL A 1 204 ? 21.46500 30.00100 13.15800  1.000 19.28000 ? 208 VAL A HG21 1 
ATOM   3087 H HG22 . VAL A 1 204 ? 20.90000 28.51700 13.19700  1.000 19.28000 ? 208 VAL A HG22 1 
ATOM   3088 H HG23 . VAL A 1 204 ? 20.46600 29.56100 14.31300  1.000 19.28000 ? 208 VAL A HG23 1 
ATOM   3089 N N    . ASP A 1 205 ? 23.79800 27.61200 17.11700  1.000 15.88875 ? 209 ASP A N    1 
ATOM   3090 C CA   . ASP A 1 205 ? 24.98200 26.99500 17.70700  1.000 16.52040 ? 209 ASP A CA   1 
ATOM   3091 C C    . ASP A 1 205 ? 24.65600 25.66400 18.37400  1.000 15.30183 ? 209 ASP A C    1 
ATOM   3092 O O    . ASP A 1 205 ? 25.44400 24.71600 18.29600  1.000 15.72557 ? 209 ASP A O    1 
ATOM   3093 C CB   . ASP A 1 205 ? 25.64500 27.94600 18.70500  1.000 18.32588 ? 209 ASP A CB   1 
ATOM   3094 C CG   . ASP A 1 205 ? 26.34500 29.09900 18.02800  1.000 20.83671 ? 209 ASP A CG   1 
ATOM   3095 O OD1  . ASP A 1 205 ? 26.48200 29.05100 16.79600  1.000 23.17383 ? 209 ASP A OD1  1 
ATOM   3096 O OD2  . ASP A 1 205 ? 26.79700 30.04100 18.71500  1.000 22.71588 ? 209 ASP A OD2  1 
ATOM   3097 H H    . ASP A 1 205 ? 23.57700 28.37000 17.45800  1.000 19.07000 ? 209 ASP A H    1 
ATOM   3098 H HA   . ASP A 1 205 ? 25.61500 26.82200 16.99300  1.000 19.83000 ? 209 ASP A HA   1 
ATOM   3099 H HB2  . ASP A 1 205 ? 24.96700 28.31000 19.29500  1.000 22.00000 ? 209 ASP A HB2  1 
ATOM   3100 H HB3  . ASP A 1 205 ? 26.30400 27.45500 19.22100  1.000 22.00000 ? 209 ASP A HB3  1 
ATOM   3101 N N    . TRP A 1 206 ? 23.52400 25.58200 19.07200  1.000 14.60701 ? 210 TRP A N    1 
ATOM   3102 C CA   . TRP A 1 206 ? 23.13900 24.31400 19.67300  1.000 14.13064 ? 210 TRP A CA   1 
ATOM   3103 C C    . TRP A 1 206 ? 22.93700 23.24900 18.61000  1.000 13.38845 ? 210 TRP A C    1 
ATOM   3104 O O    . TRP A 1 206 ? 23.43400 22.12700 18.73200  1.000 14.43331 ? 210 TRP A O    1 
ATOM   3105 C CB   . TRP A 1 206 ? 21.89600 24.47600 20.54800  1.000 15.52028 ? 210 TRP A CB   1 
ATOM   3106 C CG   . TRP A 1 206 ? 22.16500 25.10400 21.90100  1.000 16.03877 ? 210 TRP A CG   1 
ATOM   3107 C CD1  . TRP A 1 206 ? 23.33900 25.14400 22.56000  1.000 16.59146 ? 210 TRP A CD1  1 
ATOM   3108 C CD2  . TRP A 1 206 ? 21.21500 25.78000 22.73300  1.000 15.47817 ? 210 TRP A CD2  1 
ATOM   3109 N NE1  . TRP A 1 206 ? 23.19400 25.78400 23.76400  1.000 16.52040 ? 210 TRP A NE1  1 
ATOM   3110 C CE2  . TRP A 1 206 ? 21.90000 26.20200 23.88900  1.000 16.38091 ? 210 TRP A CE2  1 
ATOM   3111 C CE3  . TRP A 1 206 ? 19.85000 26.08000 22.61100  1.000 15.03338 ? 210 TRP A CE3  1 
ATOM   3112 C CZ2  . TRP A 1 206 ? 21.27000 26.89700 24.91900  1.000 16.54409 ? 210 TRP A CZ2  1 
ATOM   3113 C CZ3  . TRP A 1 206 ? 19.22700 26.76200 23.63300  1.000 16.16246 ? 210 TRP A CZ3  1 
ATOM   3114 C CH2  . TRP A 1 206 ? 19.94200 27.16900 24.77700  1.000 16.91782 ? 210 TRP A CH2  1 
ATOM   3115 H H    . TRP A 1 206 ? 22.97600 26.23200 19.20800  1.000 17.54000 ? 210 TRP A H    1 
ATOM   3116 H HA   . TRP A 1 206 ? 23.85500 24.02000 20.25700  1.000 16.96000 ? 210 TRP A HA   1 
ATOM   3117 H HB2  . TRP A 1 206 ? 21.26000 25.04200 20.08200  1.000 18.63000 ? 210 TRP A HB2  1 
ATOM   3118 H HB3  . TRP A 1 206 ? 21.50900 23.60000 20.70200  1.000 18.63000 ? 210 TRP A HB3  1 
ATOM   3119 H HD1  . TRP A 1 206 ? 24.13700 24.78600 22.24200  1.000 19.92000 ? 210 TRP A HD1  1 
ATOM   3120 H HE1  . TRP A 1 206 ? 23.81700 25.90300 24.34500  1.000 19.83000 ? 210 TRP A HE1  1 
ATOM   3121 H HE3  . TRP A 1 206 ? 19.37500 25.82400 21.85300  1.000 18.05000 ? 210 TRP A HE3  1 
ATOM   3122 H HZ2  . TRP A 1 206 ? 21.73900 27.16400 25.67600  1.000 19.86000 ? 210 TRP A HZ2  1 
ATOM   3123 H HZ3  . TRP A 1 206 ? 18.32000 26.95600 23.56700  1.000 19.40000 ? 210 TRP A HZ3  1 
ATOM   3124 H HH2  . TRP A 1 206 ? 19.49800 27.63400 25.45000  1.000 20.31000 ? 210 TRP A HH2  1 
ATOM   3125 N N    . LEU A 1 207 ? 22.22000 23.59400 17.53900  1.000 13.37529 ? 211 LEU A N    1 
ATOM   3126 C CA   . LEU A 1 207 ? 22.00900 22.63300 16.46200  1.000 13.24633 ? 211 LEU A CA   1 
ATOM   3127 C C    . LEU A 1 207 ? 23.31900 22.21600 15.82100  1.000 12.77258 ? 211 LEU A C    1 
ATOM   3128 O O    . LEU A 1 207 ? 23.50400 21.03800 15.49700  1.000 13.31475 ? 211 LEU A O    1 
ATOM   3129 C CB   . LEU A 1 207 ? 21.08200 23.23300 15.40900  1.000 13.53320 ? 211 LEU A CB   1 
ATOM   3130 C CG   . LEU A 1 207 ? 19.64300 23.48200 15.87300  1.000 13.91483 ? 211 LEU A CG   1 
ATOM   3131 C CD1  . LEU A 1 207 ? 18.95600 24.40700 14.87500  1.000 14.71229 ? 211 LEU A CD1  1 
ATOM   3132 C CD2  . LEU A 1 207 ? 18.82900 22.21200 16.05300  1.000 13.46740 ? 211 LEU A CD2  1 
ATOM   3133 H H    . LEU A 1 207 ? 21.85400 24.36200 17.41500  1.000 16.06000 ? 211 LEU A H    1 
ATOM   3134 H HA   . LEU A 1 207 ? 21.58800 21.84200 16.83400  1.000 15.90000 ? 211 LEU A HA   1 
ATOM   3135 H HB2  . LEU A 1 207 ? 21.44800 24.08700 15.12900  1.000 16.24000 ? 211 LEU A HB2  1 
ATOM   3136 H HB3  . LEU A 1 207 ? 21.04300 22.62500 14.65400  1.000 16.24000 ? 211 LEU A HB3  1 
ATOM   3137 H HG   . LEU A 1 207 ? 19.68200 23.89100 16.75100  1.000 16.71000 ? 211 LEU A HG   1 
ATOM   3138 H HD11 . LEU A 1 207 ? 18.04000 24.55300 15.15800  1.000 17.66000 ? 211 LEU A HD11 1 
ATOM   3139 H HD12 . LEU A 1 207 ? 19.43300 25.25200 14.84800  1.000 17.66000 ? 211 LEU A HD12 1 
ATOM   3140 H HD13 . LEU A 1 207 ? 18.97000 23.99200 13.99900  1.000 17.66000 ? 211 LEU A HD13 1 
ATOM   3141 H HD21 . LEU A 1 207 ? 17.93000 22.44900 16.32800  1.000 16.17000 ? 211 LEU A HD21 1 
ATOM   3142 H HD22 . LEU A 1 207 ? 18.80100 21.73200 15.21000  1.000 16.17000 ? 211 LEU A HD22 1 
ATOM   3143 H HD23 . LEU A 1 207 ? 19.24900 21.66200 16.73200  1.000 16.17000 ? 211 LEU A HD23 1 
ATOM   3144 N N    . LYS A 1 208 ? 24.22500 23.16800 15.60700  1.000 13.32791 ? 212 LYS A N    1 
ATOM   3145 C CA   . LYS A 1 208 ? 25.51600 22.83400 15.00700  1.000 14.37278 ? 212 LYS A CA   1 
ATOM   3146 C C    . LYS A 1 208 ? 26.30300 21.86100 15.87100  1.000 14.90179 ? 212 LYS A C    1 
ATOM   3147 O O    . LYS A 1 208 ? 27.04500 21.03100 15.34700  1.000 15.72294 ? 212 LYS A O    1 
ATOM   3148 C CB   . LYS A 1 208 ? 26.33200 24.10300 14.77700  1.000 15.43606 ? 212 LYS A CB   1 
ATOM   3149 C CG   . LYS A 1 208 ? 25.90600 24.91300 13.56000  1.000 17.79687 ? 212 LYS A CG   1 
ATOM   3150 C CD   . LYS A 1 208 ? 26.75100 26.17700 13.48500  1.000 21.95526 ? 212 LYS A CD   1 
ATOM   3151 C CE   . LYS A 1 208 ? 26.75900 26.87200 12.16300  1.000 25.29777 ? 212 LYS A CE   1 
ATOM   3152 N NZ   . LYS A 1 208 ? 27.93800 27.82600 12.17900  1.000 26.63740 ? 212 LYS A NZ   1 
ATOM   3153 H H    . LYS A 1 208 ? 24.12100 24.00000 15.79600  1.000 16.00000 ? 212 LYS A H    1 
ATOM   3154 H HA   . LYS A 1 208 ? 25.35600 22.41400 14.14800  1.000 17.26000 ? 212 LYS A HA   1 
ATOM   3155 H HB2  . LYS A 1 208 ? 26.24100 24.67500 15.55500  1.000 18.53000 ? 212 LYS A HB2  1 
ATOM   3156 H HB3  . LYS A 1 208 ? 27.26100 23.85500 14.65300  1.000 18.53000 ? 212 LYS A HB3  1 
ATOM   3157 H HG2  . LYS A 1 208 ? 26.04400 24.39300 12.75300  1.000 21.37000 ? 212 LYS A HG2  1 
ATOM   3158 H HG3  . LYS A 1 208 ? 24.97200 25.16200 13.63900  1.000 21.37000 ? 212 LYS A HG3  1 
ATOM   3159 H HD2  . LYS A 1 208 ? 26.41400 26.80900 14.13900  1.000 26.35000 ? 212 LYS A HD2  1 
ATOM   3160 H HD3  . LYS A 1 208 ? 27.67000 25.94300 13.69100  1.000 26.35000 ? 212 LYS A HD3  1 
ATOM   3161 H HE2  . LYS A 1 208 ? 26.87000 26.23100 11.44300  1.000 30.37000 ? 212 LYS A HE2  1 
ATOM   3162 H HE3  . LYS A 1 208 ? 25.93800 27.37200 12.03800  1.000 30.37000 ? 212 LYS A HE3  1 
ATOM   3163 H HZ1  . LYS A 1 208 ? 27.99400 28.25300 11.40100  1.000 31.97000 ? 212 LYS A HZ1  1 
ATOM   3164 H HZ2  . LYS A 1 208 ? 27.83700 28.42300 12.83000  1.000 31.97000 ? 212 LYS A HZ2  1 
ATOM   3165 H HZ3  . LYS A 1 208 ? 28.69300 27.37400 12.31600  1.000 31.97000 ? 212 LYS A HZ3  1 
ATOM   3166 N N    . GLY A 1 209 ? 26.14400 21.94400 17.19200  1.000 14.77546 ? 213 GLY A N    1 
ATOM   3167 C CA   . GLY A 1 209 ? 26.82500 21.06900 18.11100  1.000 15.04128 ? 213 GLY A CA   1 
ATOM   3168 C C    . GLY A 1 209 ? 26.15900 19.74300 18.35300  1.000 14.49647 ? 213 GLY A C    1 
ATOM   3169 O O    . GLY A 1 209 ? 26.59500 18.99600 19.22500  1.000 15.49659 ? 213 GLY A O    1 
ATOM   3170 H H    . GLY A 1 209 ? 25.63200 22.51700 17.57800  1.000 17.74000 ? 213 GLY A H    1 
ATOM   3171 H HA2  . GLY A 1 209 ? 27.71400 20.89200 17.76600  1.000 18.06000 ? 213 GLY A HA2  1 
ATOM   3172 H HA3  . GLY A 1 209 ? 26.90100 21.51900 18.96600  1.000 18.06000 ? 213 GLY A HA3  1 
ATOM   3173 N N    . ASN A 1 210 ? 25.10100 19.40500 17.61200  1.000 13.56215 ? 214 ASN A N    1 
ATOM   3174 C CA   . ASN A 1 210 ? 24.44500 18.13000 17.84300  1.000 13.79902 ? 214 ASN A CA   1 
ATOM   3175 C C    . ASN A 1 210 ? 25.41300 16.98000 17.62100  1.000 14.30171 ? 214 ASN A C    1 
ATOM   3176 O O    . ASN A 1 210 ? 26.19100 16.97200 16.65900  1.000 14.75440 ? 214 ASN A O    1 
ATOM   3177 C CB   . ASN A 1 210 ? 23.24500 17.94300 16.92100  1.000 14.00168 ? 214 ASN A CB   1 
ATOM   3178 C CG   . ASN A 1 210 ? 22.53500 16.64200 17.19800  1.000 13.86219 ? 214 ASN A CG   1 
ATOM   3179 O OD1  . ASN A 1 210 ? 22.45800 16.20800 18.33900  1.000 14.33067 ? 214 ASN A OD1  1 
ATOM   3180 N ND2  . ASN A 1 210 ? 22.05600 15.97900 16.16000  1.000 14.53332 ? 214 ASN A ND2  1 
ATOM   3181 H H    . ASN A 1 210 ? 24.75700 19.88700 16.98800  1.000 16.28000 ? 214 ASN A H    1 
ATOM   3182 H HA   . ASN A 1 210 ? 24.13100 18.11900 18.76100  1.000 16.57000 ? 214 ASN A HA   1 
ATOM   3183 H HB2  . ASN A 1 210 ? 22.61800 18.66900 17.06000  1.000 16.81000 ? 214 ASN A HB2  1 
ATOM   3184 H HB3  . ASN A 1 210 ? 23.54700 17.93600 15.99900  1.000 16.81000 ? 214 ASN A HB3  1 
ATOM   3185 H HD21 . ASN A 1 210 ? 21.64500 15.23300 16.27800  1.000 17.45000 ? 214 ASN A HD21 1 
ATOM   3186 H HD22 . ASN A 1 210 ? 22.15600 16.29400 15.36500  1.000 17.45000 ? 214 ASN A HD22 1 
ATOM   3187 N N    . THR A 1 211 ? 25.32100 15.98000 18.48700  1.000 14.28592 ? 215 THR A N    1 
ATOM   3188 C CA   . THR A 1 211 ? 26.18500 14.81700 18.41400  1.000 14.27276 ? 215 THR A CA   1 
ATOM   3189 C C    . THR A 1 211 ? 25.51300 13.56400 17.86900  1.000 14.22539 ? 215 THR A C    1 
ATOM   3190 O O    . THR A 1 211 ? 26.20900 12.56300 17.64800  1.000 14.85704 ? 215 THR A O    1 
ATOM   3191 C CB   . THR A 1 211 ? 26.79500 14.46300 19.78400  1.000 14.69913 ? 215 THR A CB   1 
ATOM   3192 O OG1  . THR A 1 211 ? 25.77600 13.91000 20.63700  1.000 15.09918 ? 215 THR A OG1  1 
ATOM   3193 C CG2  . THR A 1 211 ? 27.41300 15.66600 20.45600  1.000 15.91507 ? 215 THR A CG2  1 
ATOM   3194 H H    . THR A 1 211 ? 24.75600 15.95400 19.13500  1.000 17.15000 ? 215 THR A H    1 
ATOM   3195 H HA   . THR A 1 211 ? 26.91200 15.06100 17.81900  1.000 17.13000 ? 215 THR A HA   1 
ATOM   3196 H HB   . THR A 1 211 ? 27.50200 13.81200 19.64900  1.000 17.65000 ? 215 THR A HB   1 
ATOM   3197 H HG1  . THR A 1 211 ? 25.17500 14.48000 20.77400  1.000 18.13000 ? 215 THR A HG1  1 
ATOM   3198 H HG21 . THR A 1 211 ? 27.83800 15.40000 21.28600  1.000 19.11000 ? 215 THR A HG21 1 
ATOM   3199 H HG22 . THR A 1 211 ? 28.08000 16.06400 19.87400  1.000 19.11000 ? 215 THR A HG22 1 
ATOM   3200 H HG23 . THR A 1 211 ? 26.73000 16.32600 20.64900  1.000 19.11000 ? 215 THR A HG23 1 
ATOM   3201 N N    . THR A 1 212 ? 24.18600 13.57200 17.65700  1.000 14.43068 ? 216 THR A N    1 
ATOM   3202 C CA   . THR A 1 212 ? 23.44200 12.34600 17.40100  1.000 14.68597 ? 216 THR A CA   1 
ATOM   3203 C C    . THR A 1 212 ? 23.08300 12.15900 15.93000  1.000 14.71755 ? 216 THR A C    1 
ATOM   3204 O O    . THR A 1 212 ? 22.44700 11.15100 15.59400  1.000 14.80967 ? 216 THR A O    1 
ATOM   3205 C CB   . THR A 1 212 ? 22.12800 12.35300 18.19000  1.000 14.64912 ? 216 THR A CB   1 
ATOM   3206 O OG1  . THR A 1 212 ? 21.31400 13.39600 17.65800  1.000 16.02824 ? 216 THR A OG1  1 
ATOM   3207 C CG2  . THR A 1 212 ? 22.35200 12.60400 19.67100  1.000 15.97823 ? 216 THR A CG2  1 
ATOM   3208 H H    . THR A 1 212 ? 23.70100 14.28200 17.65700  1.000 17.32000 ? 216 THR A H    1 
ATOM   3209 H HA   . THR A 1 212 ? 23.99400 11.60300 17.69200  1.000 17.63000 ? 216 THR A HA   1 
ATOM   3210 H HB   . THR A 1 212 ? 21.69400 11.48900 18.11500  1.000 17.59000 ? 216 THR A HB   1 
ATOM   3211 H HG1  . THR A 1 212 ? 20.58000 13.42200 18.06400  1.000 19.24000 ? 216 THR A HG1  1 
ATOM   3212 H HG21 . THR A 1 212 ? 21.51400 12.52100 20.15200  1.000 19.18000 ? 216 THR A HG21 1 
ATOM   3213 H HG22 . THR A 1 212 ? 22.98300 11.95800 20.02400  1.000 19.18000 ? 216 THR A HG22 1 
ATOM   3214 H HG23 . THR A 1 212 ? 22.70700 13.49700 19.80600  1.000 19.18000 ? 216 THR A HG23 1 
ATOM   3215 N N    . GLY A 1 213 ? 23.46800 13.08900 15.05700  1.000 14.22013 ? 217 GLY A N    1 
ATOM   3216 C CA   . GLY A 1 213 ? 23.00100 13.04200 13.68000  1.000 13.84903 ? 217 GLY A CA   1 
ATOM   3217 C C    . GLY A 1 213 ? 24.05100 12.74200 12.63500  1.000 13.89377 ? 217 GLY A C    1 
ATOM   3218 O O    . GLY A 1 213 ? 23.81700 13.03400 11.46100  1.000 14.05168 ? 217 GLY A O    1 
ATOM   3219 H H    . GLY A 1 213 ? 23.99100 13.74700 15.23800  1.000 17.07000 ? 217 GLY A H    1 
ATOM   3220 H HA2  . GLY A 1 213 ? 22.31800 12.35700 13.61000  1.000 16.63000 ? 217 GLY A HA2  1 
ATOM   3221 H HA3  . GLY A 1 213 ? 22.60900 13.90200 13.45900  1.000 16.63000 ? 217 GLY A HA3  1 
ATOM   3222 N N    . ASN A 1 214 ? 25.18300 12.15700 13.01100  1.000 14.46752 ? 218 ASN A N    1 
ATOM   3223 C CA   . ASN A 1 214 ? 26.25400 12.02400 12.02600  1.000 15.14392 ? 218 ASN A CA   1 
ATOM   3224 C C    . ASN A 1 214 ? 25.90300 11.09000 10.88300  1.000 15.26236 ? 218 ASN A C    1 
ATOM   3225 O O    . ASN A 1 214 ? 26.55900 11.15600 9.83900   1.000 16.35986 ? 218 ASN A O    1 
ATOM   3226 C CB   . ASN A 1 214 ? 27.52300 11.53900 12.71500  1.000 16.28616 ? 218 ASN A CB   1 
ATOM   3227 C CG   . ASN A 1 214 ? 28.06500 12.56000 13.68700  1.000 19.23652 ? 218 ASN A CG   1 
ATOM   3228 O OD1  . ASN A 1 214 ? 27.77900 13.75300 13.57400  1.000 19.80764 ? 218 ASN A OD1  1 
ATOM   3229 N ND2  . ASN A 1 214 ? 28.84900 12.10600 14.65300  1.000 22.67114 ? 218 ASN A ND2  1 
ATOM   3230 H H    . ASN A 1 214 ? 25.35000 11.84200 13.79300  1.000 17.37000 ? 218 ASN A H    1 
ATOM   3231 H HA   . ASN A 1 214 ? 26.42300 12.89700 11.64000  1.000 18.18000 ? 218 ASN A HA   1 
ATOM   3232 H HB2  . ASN A 1 214 ? 27.32900 10.72600 13.20700  1.000 19.55000 ? 218 ASN A HB2  1 
ATOM   3233 H HB3  . ASN A 1 214 ? 28.20400 11.36600 12.04600  1.000 19.55000 ? 218 ASN A HB3  1 
ATOM   3234 H HD21 . ASN A 1 214 ? 29.18000 12.65100 15.22900  1.000 27.21000 ? 218 ASN A HD21 1 
ATOM   3235 H HD22 . ASN A 1 214 ? 29.02600 11.26600 14.70400  1.000 27.21000 ? 218 ASN A HD22 1 
ATOM   3236 N N    . HIS A 1 215 ? 24.93000 10.19700 11.06000  1.000 13.75428 ? 219 HIS A N    1 
ATOM   3237 C CA   . HIS A 1 215 ? 24.58500 9.22200  10.03500  1.000 14.31751 ? 219 HIS A CA   1 
ATOM   3238 C C    . HIS A 1 215 ? 23.32200 9.58400  9.27200   1.000 14.45436 ? 219 HIS A C    1 
ATOM   3239 O O    . HIS A 1 215 ? 22.83000 8.76900  8.48700   1.000 15.03865 ? 219 HIS A O    1 
ATOM   3240 C CB   . HIS A 1 215 ? 24.48000 7.82600  10.64500  1.000 16.26511 ? 219 HIS A CB   1 
ATOM   3241 C CG   . HIS A 1 215 ? 25.73400 7.40700  11.34500  1.000 20.11294 ? 219 HIS A CG   1 
ATOM   3242 N ND1  . HIS A 1 215 ? 26.93100 7.24300  10.67700  1.000 22.18424 ? 219 HIS A ND1  1 
ATOM   3243 C CD2  . HIS A 1 215 ? 25.99700 7.17600  12.65300  1.000 22.95012 ? 219 HIS A CD2  1 
ATOM   3244 C CE1  . HIS A 1 215 ? 27.86700 6.90100  11.54300  1.000 23.87392 ? 219 HIS A CE1  1 
ATOM   3245 N NE2  . HIS A 1 215 ? 27.32400 6.84900  12.74500  1.000 24.66875 ? 219 HIS A NE2  1 
ATOM   3246 H H    . HIS A 1 215 ? 24.45300 10.13800 11.77400  1.000 16.51000 ? 219 HIS A H    1 
ATOM   3247 H HA   . HIS A 1 215 ? 25.30400 9.19400  9.38400   1.000 17.19000 ? 219 HIS A HA   1 
ATOM   3248 H HB2  . HIS A 1 215 ? 23.75800 7.81700  11.29300  1.000 19.52000 ? 219 HIS A HB2  1 
ATOM   3249 H HB3  . HIS A 1 215 ? 24.30100 7.18500  9.94000   1.000 19.52000 ? 219 HIS A HB3  1 
ATOM   3250 H HD2  . HIS A 1 215 ? 25.39100 7.22900  13.35600  1.000 27.55000 ? 219 HIS A HD2  1 
ATOM   3251 H HE1  . HIS A 1 215 ? 28.75700 6.72700  11.34000  1.000 28.66000 ? 219 HIS A HE1  1 
ATOM   3252 H HE2  . HIS A 1 215 ? 27.73800 6.64400  13.47000  1.000 29.61000 ? 219 HIS A HE2  1 
ATOM   3253 N N    . ARG A 1 216 ? 22.80700 10.79000 9.45500   1.000 13.66480 ? 220 ARG A N    1 
ATOM   3254 C CA   . ARG A 1 216 ? 21.54700 11.21500 8.86200   1.000 13.15158 ? 220 ARG A CA   1 
ATOM   3255 C C    . ARG A 1 216 ? 21.82900 12.36300 7.86700   1.000 12.78311 ? 220 ARG A C    1 
ATOM   3256 O O    . ARG A 1 216 ? 22.62800 12.14700 6.95200   1.000 13.57005 ? 220 ARG A O    1 
ATOM   3257 C CB   . ARG A 1 216 ? 20.55500 11.47700 9.98800   1.000 12.66994 ? 220 ARG A CB   1 
ATOM   3258 C CG   . ARG A 1 216 ? 20.20000 10.16500 10.70100  1.000 13.29896 ? 220 ARG A CG   1 
ATOM   3259 C CD   . ARG A 1 216 ? 19.17900 10.32900 11.79700  1.000 13.15684 ? 220 ARG A CD   1 
ATOM   3260 N NE   . ARG A 1 216 ? 19.08000 9.08700  12.54400  1.000 13.27791 ? 220 ARG A NE   1 
ATOM   3261 C CZ   . ARG A 1 216 ? 18.11100 8.80200  13.40300  1.000 13.85166 ? 220 ARG A CZ   1 
ATOM   3262 N NH1  . ARG A 1 216 ? 17.05300 9.59200  13.54300  1.000 13.23317 ? 220 ARG A NH1  1 
ATOM   3263 N NH2  . ARG A 1 216 ? 18.18800 7.68000  14.10700  1.000 15.69136 ? 220 ARG A NH2  1 
ATOM   3264 H H    . ARG A 1 216 ? 23.18000 11.39900 9.93300   1.000 16.41000 ? 220 ARG A H    1 
ATOM   3265 H HA   . ARG A 1 216 ? 21.18200 10.49900 8.31900   1.000 15.79000 ? 220 ARG A HA   1 
ATOM   3266 H HB2  . ARG A 1 216 ? 20.94900 12.08500 10.63300  1.000 15.21000 ? 220 ARG A HB2  1 
ATOM   3267 H HB3  . ARG A 1 216 ? 19.74300 11.86200 9.62200   1.000 15.21000 ? 220 ARG A HB3  1 
ATOM   3268 H HG2  . ARG A 1 216 ? 19.83900 9.54300  10.05100  1.000 15.96000 ? 220 ARG A HG2  1 
ATOM   3269 H HG3  . ARG A 1 216 ? 21.00500 9.79800  11.10000  1.000 15.96000 ? 220 ARG A HG3  1 
ATOM   3270 H HD2  . ARG A 1 216 ? 19.45200 11.03800 12.40000  1.000 15.80000 ? 220 ARG A HD2  1 
ATOM   3271 H HD3  . ARG A 1 216 ? 18.31300 10.53500 11.41300  1.000 15.80000 ? 220 ARG A HD3  1 
ATOM   3272 H HE   . ARG A 1 216 ? 19.69300 8.49600  12.42100  1.000 15.94000 ? 220 ARG A HE   1 
ATOM   3273 H HH11 . ARG A 1 216 ? 16.98500 10.30700 13.07100  1.000 15.89000 ? 220 ARG A HH11 1 
ATOM   3274 H HH12 . ARG A 1 216 ? 16.43600 9.38800  14.10600  1.000 15.89000 ? 220 ARG A HH12 1 
ATOM   3275 H HH21 . ARG A 1 216 ? 18.85800 7.15100  14.00100  1.000 18.84000 ? 220 ARG A HH21 1 
ATOM   3276 H HH22 . ARG A 1 216 ? 17.56700 7.48100  14.66800  1.000 18.84000 ? 220 ARG A HH22 1 
ATOM   3277 N N    . ILE A 1 217 ? 21.19200 13.52100 7.98700   1.000 12.76469 ? 221 ILE A N    1 
ATOM   3278 C CA   . ILE A 1 217 ? 21.38600 14.57100 6.99300   1.000 12.63573 ? 221 ILE A CA   1 
ATOM   3279 C C    . ILE A 1 217 ? 22.87000 14.89800 6.85000   1.000 13.33844 ? 221 ILE A C    1 
ATOM   3280 O O    . ILE A 1 217 ? 23.36800 15.11100 5.73000   1.000 13.90956 ? 221 ILE A O    1 
ATOM   3281 C CB   . ILE A 1 217 ? 20.53200 15.80900 7.32800   1.000 12.08566 ? 221 ILE A CB   1 
ATOM   3282 C CG1  . ILE A 1 217 ? 19.03800 15.47400 7.16000   1.000 12.48308 ? 221 ILE A CG1  1 
ATOM   3283 C CG2  . ILE A 1 217 ? 20.92000 16.98100 6.43200   1.000 12.48308 ? 221 ILE A CG2  1 
ATOM   3284 C CD1  . ILE A 1 217 ? 18.13300 16.49000 7.75600   1.000 12.46728 ? 221 ILE A CD1  1 
ATOM   3285 H H    . ILE A 1 217 ? 20.65000 13.72300 8.62300   1.000 15.32000 ? 221 ILE A H    1 
ATOM   3286 H HA   . ILE A 1 217 ? 21.07800 14.24500 6.13400   1.000 15.17000 ? 221 ILE A HA   1 
ATOM   3287 H HB   . ILE A 1 217 ? 20.69700 16.06000 8.25000   1.000 14.51000 ? 221 ILE A HB   1 
ATOM   3288 H HG12 . ILE A 1 217 ? 18.83500 15.41500 6.21400   1.000 14.99000 ? 221 ILE A HG12 1 
ATOM   3289 H HG13 . ILE A 1 217 ? 18.85700 14.62500 7.59200   1.000 14.99000 ? 221 ILE A HG13 1 
ATOM   3290 H HG21 . ILE A 1 217 ? 20.24400 17.67300 6.50600   1.000 14.99000 ? 221 ILE A HG21 1 
ATOM   3291 H HG22 . ILE A 1 217 ? 21.78000 17.32700 6.71900   1.000 14.99000 ? 221 ILE A HG22 1 
ATOM   3292 H HG23 . ILE A 1 217 ? 20.97800 16.67200 5.51400   1.000 14.99000 ? 221 ILE A HG23 1 
ATOM   3293 H HD11 . ILE A 1 217 ? 17.22100 16.16200 7.71600   1.000 14.97000 ? 221 ILE A HD11 1 
ATOM   3294 H HD12 . ILE A 1 217 ? 18.39100 16.63900 8.67900   1.000 14.97000 ? 221 ILE A HD12 1 
ATOM   3295 H HD13 . ILE A 1 217 ? 18.21100 17.31600 7.25400   1.000 14.97000 ? 221 ILE A HD13 1 
ATOM   3296 N N    . ARG A 1 218 ? 23.60600 14.92800 7.97500   1.000 13.66743 ? 222 ARG A N    1 
ATOM   3297 C CA   . ARG A 1 218 ? 25.03000 15.26600 7.92800   1.000 14.42805 ? 222 ARG A CA   1 
ATOM   3298 C C    . ARG A 1 218 ? 25.81200 14.33700 7.00900   1.000 14.71229 ? 222 ARG A C    1 
ATOM   3299 O O    . ARG A 1 218 ? 26.81600 14.76000 6.42300   1.000 15.42027 ? 222 ARG A O    1 
ATOM   3300 C CB   . ARG A 1 218 ? 25.63600 15.21400 9.33500   1.000 14.28066 ? 222 ARG A CB   1 
ATOM   3301 C CG   . ARG A 1 218 ? 25.28500 16.39700 10.19300  1.000 15.29394 ? 222 ARG A CG   1 
ATOM   3302 C CD   . ARG A 1 218 ? 25.70600 16.16500 11.62100  1.000 16.26248 ? 222 ARG A CD   1 
ATOM   3303 N NE   . ARG A 1 218 ? 25.19100 17.20700 12.49700  1.000 15.47554 ? 222 ARG A NE   1 
ATOM   3304 C CZ   . ARG A 1 218 ? 25.84200 18.30400 12.83700  1.000 16.77306 ? 222 ARG A CZ   1 
ATOM   3305 N NH1  . ARG A 1 218 ? 27.05300 18.56500 12.36600  1.000 18.31535 ? 222 ARG A NH1  1 
ATOM   3306 N NH2  . ARG A 1 218 ? 25.26200 19.17000 13.65900  1.000 16.95203 ? 222 ARG A NH2  1 
ATOM   3307 H H    . ARG A 1 218 ? 23.30600 14.76000 8.76300   1.000 16.41000 ? 222 ARG A H    1 
ATOM   3308 H HA   . ARG A 1 218 ? 25.10900 16.17100 7.58700   1.000 17.32000 ? 222 ARG A HA   1 
ATOM   3309 H HB2  . ARG A 1 218 ? 25.31300 14.41700 9.78300   1.000 17.14000 ? 222 ARG A HB2  1 
ATOM   3310 H HB3  . ARG A 1 218 ? 26.60200 15.18200 9.25600   1.000 17.14000 ? 222 ARG A HB3  1 
ATOM   3311 H HG2  . ARG A 1 218 ? 25.74300 17.18500 9.86200   1.000 18.36000 ? 222 ARG A HG2  1 
ATOM   3312 H HG3  . ARG A 1 218 ? 24.32600 16.53800 10.17400  1.000 18.36000 ? 222 ARG A HG3  1 
ATOM   3313 H HD2  . ARG A 1 218 ? 25.36000 15.31100 11.92400  1.000 19.52000 ? 222 ARG A HD2  1 
ATOM   3314 H HD3  . ARG A 1 218 ? 26.67500 16.16900 11.67600  1.000 19.52000 ? 222 ARG A HD3  1 
ATOM   3315 H HE   . ARG A 1 218 ? 24.40100 17.09900 12.81900  1.000 18.58000 ? 222 ARG A HE   1 
ATOM   3316 H HH11 . ARG A 1 218 ? 27.43200 18.01400 11.82600  1.000 21.99000 ? 222 ARG A HH11 1 
ATOM   3317 H HH12 . ARG A 1 218 ? 27.45900 19.28600 12.60000  1.000 21.99000 ? 222 ARG A HH12 1 
ATOM   3318 H HH21 . ARG A 1 218 ? 24.47300 19.01200 13.96200  1.000 20.35000 ? 222 ARG A HH21 1 
ATOM   3319 H HH22 . ARG A 1 218 ? 25.67600 19.88800 13.88800  1.000 20.35000 ? 222 ARG A HH22 1 
ATOM   3320 N N    . ALA A 1 219 ? 25.40700 13.06500 6.90800   1.000 14.74124 ? 223 ALA A N    1 
ATOM   3321 C CA   . ALA A 1 219 ? 26.09000 12.10900 6.03700   1.000 15.97560 ? 223 ALA A CA   1 
ATOM   3322 C C    . ALA A 1 219 ? 25.91100 12.42600 4.56600   1.000 17.17048 ? 223 ALA A C    1 
ATOM   3323 O O    . ALA A 1 219 ? 26.65100 11.88100 3.74200   1.000 18.56802 ? 223 ALA A O    1 
ATOM   3324 C CB   . ALA A 1 219 ? 25.62900 10.67900 6.33500   1.000 17.09942 ? 223 ALA A CB   1 
ATOM   3325 H H    . ALA A 1 219 ? 24.73800 12.73300 7.33400   1.000 17.70000 ? 223 ALA A H    1 
ATOM   3326 H HA   . ALA A 1 219 ? 27.03900 12.14300 6.23000   1.000 19.18000 ? 223 ALA A HA   1 
ATOM   3327 H HB1  . ALA A 1 219 ? 26.08700 10.06800 5.73600   1.000 20.53000 ? 223 ALA A HB1  1 
ATOM   3328 H HB2  . ALA A 1 219 ? 25.84500 10.46300 7.25600   1.000 20.53000 ? 223 ALA A HB2  1 
ATOM   3329 H HB3  . ALA A 1 219 ? 24.67100 10.62100 6.19800   1.000 20.53000 ? 223 ALA A HB3  1 
ATOM   3330 N N    . ALA A 1 220 ? 24.96100 13.29100 4.22500   1.000 17.17311 ? 224 ALA A N    1 
ATOM   3331 C CA   . ALA A 1 220 ? 24.73500 13.72300 2.85600   1.000 17.37577 ? 224 ALA A CA   1 
ATOM   3332 C C    . ALA A 1 220 ? 25.38000 15.06500 2.54300   1.000 17.55474 ? 224 ALA A C    1 
ATOM   3333 O O    . ALA A 1 220 ? 25.27300 15.53500 1.40700   1.000 20.17084 ? 224 ALA A O    1 
ATOM   3334 C CB   . ALA A 1 220 ? 23.22800 13.82900 2.59600   1.000 19.09439 ? 224 ALA A CB   1 
ATOM   3335 H H    . ALA A 1 220 ? 24.41900 13.65000 4.78800   1.000 20.62000 ? 224 ALA A H    1 
ATOM   3336 H HA   . ALA A 1 220 ? 25.11200 13.06000 2.25700   1.000 20.86000 ? 224 ALA A HA   1 
ATOM   3337 H HB1  . ALA A 1 220 ? 23.08500 14.12400 1.68300   1.000 22.92000 ? 224 ALA A HB1  1 
ATOM   3338 H HB2  . ALA A 1 220 ? 22.82200 12.95800 2.73000   1.000 22.92000 ? 224 ALA A HB2  1 
ATOM   3339 H HB3  . ALA A 1 220 ? 22.84500 14.47100 3.21500   1.000 22.92000 ? 224 ALA A HB3  1 
ATOM   3340 N N    . VAL A 1 221 ? 26.04600 15.68300 3.50700   1.000 18.11007 ? 225 VAL A N    1 
ATOM   3341 C CA   . VAL A 1 221 ? 26.50300 17.07200 3.42700   1.000 20.03398 ? 225 VAL A CA   1 
ATOM   3342 C C    . VAL A 1 221 ? 28.02900 17.07100 3.38700   1.000 20.44982 ? 225 VAL A C    1 
ATOM   3343 O O    . VAL A 1 221 ? 28.66100 16.49400 4.28300   1.000 21.46836 ? 225 VAL A O    1 
ATOM   3344 C CB   . VAL A 1 221 ? 26.00200 17.88200 4.64200   1.000 21.07621 ? 225 VAL A CB   1 
ATOM   3345 C CG1  . VAL A 1 221 ? 26.61000 19.26600 4.65000   1.000 23.21331 ? 225 VAL A CG1  1 
ATOM   3346 C CG2  . VAL A 1 221 ? 24.46900 17.98600 4.64100   1.000 22.16055 ? 225 VAL A CG2  1 
ATOM   3347 H H    . VAL A 1 221 ? 26.25600 15.30600 4.25000   1.000 21.74000 ? 225 VAL A H    1 
ATOM   3348 H HA   . VAL A 1 221 ? 26.17800 17.48000 2.60900   1.000 24.05000 ? 225 VAL A HA   1 
ATOM   3349 H HB   . VAL A 1 221 ? 26.27700 17.41800 5.44800   1.000 25.30000 ? 225 VAL A HB   1 
ATOM   3350 H HG11 . VAL A 1 221 ? 25.93600 19.90600 4.93100   1.000 27.86000 ? 225 VAL A HG11 1 
ATOM   3351 H HG12 . VAL A 1 221 ? 27.35700 19.28000 5.26800   1.000 27.86000 ? 225 VAL A HG12 1 
ATOM   3352 H HG13 . VAL A 1 221 ? 26.91700 19.48200 3.75500   1.000 27.86000 ? 225 VAL A HG13 1 
ATOM   3353 H HG21 . VAL A 1 221 ? 24.18000 18.40200 5.46800   1.000 26.60000 ? 225 VAL A HG21 1 
ATOM   3354 H HG22 . VAL A 1 221 ? 24.18900 18.52400 3.88400   1.000 26.60000 ? 225 VAL A HG22 1 
ATOM   3355 H HG23 . VAL A 1 221 ? 24.09200 17.09500 4.57000   1.000 26.60000 ? 225 VAL A HG23 1 
ATOM   3356 N N    . PRO A 1 222 ? 28.66200 17.70200 2.38900   1.000 20.34191 ? 226 PRO A N    1 
ATOM   3357 C CA   . PRO A 1 222 ? 30.13000 17.74900 2.35300   1.000 20.62353 ? 226 PRO A CA   1 
ATOM   3358 C C    . PRO A 1 222 ? 30.73800 18.30800 3.63200   1.000 20.69722 ? 226 PRO A C    1 
ATOM   3359 O O    . PRO A 1 222 ? 30.16600 19.18000 4.29500   1.000 20.23664 ? 226 PRO A O    1 
ATOM   3360 C CB   . PRO A 1 222 ? 30.42700 18.65800 1.15400   1.000 20.12610 ? 226 PRO A CB   1 
ATOM   3361 C CG   . PRO A 1 222 ? 29.25900 18.49700 0.28400   1.000 20.79460 ? 226 PRO A CG   1 
ATOM   3362 C CD   . PRO A 1 222 ? 28.07300 18.33600 1.19800   1.000 20.72091 ? 226 PRO A CD   1 
ATOM   3363 H HA   . PRO A 1 222 ? 30.48100 16.85700 2.20200   1.000 24.76000 ? 226 PRO A HA   1 
ATOM   3364 H HB2  . PRO A 1 222 ? 30.52100 19.57800 1.44800   1.000 24.16000 ? 226 PRO A HB2  1 
ATOM   3365 H HB3  . PRO A 1 222 ? 31.23900 18.36800 0.70900   1.000 24.16000 ? 226 PRO A HB3  1 
ATOM   3366 H HG2  . PRO A 1 222 ? 29.15700 19.28400 -0.27400  1.000 24.96000 ? 226 PRO A HG2  1 
ATOM   3367 H HG3  . PRO A 1 222 ? 29.37200 17.71000 -0.27100  1.000 24.96000 ? 226 PRO A HG3  1 
ATOM   3368 H HD2  . PRO A 1 222 ? 27.68600 19.19700 1.42000   1.000 24.87000 ? 226 PRO A HD2  1 
ATOM   3369 H HD3  . PRO A 1 222 ? 27.40100 17.76300 0.79700   1.000 24.87000 ? 226 PRO A HD3  1 
ATOM   3370 N N    . ALA A 1 223 ? 31.94900 17.83300 3.93000   1.000 21.33677 ? 227 ALA A N    1 
ATOM   3371 C CA   . ALA A 1 223 ? 32.60700 18.14200 5.19200   1.000 22.40532 ? 227 ALA A CA   1 
ATOM   3372 C C    . ALA A 1 223 ? 32.92200 19.62200 5.35900   1.000 20.94725 ? 227 ALA A C    1 
ATOM   3373 O O    . ALA A 1 223 ? 33.09300 20.07800 6.49500   1.000 22.86064 ? 227 ALA A O    1 
ATOM   3374 C CB   . ALA A 1 223 ? 33.91000 17.34000 5.28800   1.000 24.05288 ? 227 ALA A CB   1 
ATOM   3375 H H    . ALA A 1 223 ? 32.41100 17.32500 3.41300   1.000 25.61000 ? 227 ALA A H    1 
ATOM   3376 H HA   . ALA A 1 223 ? 32.01200 17.88800 5.91500   1.000 26.90000 ? 227 ALA A HA   1 
ATOM   3377 H HB1  . ALA A 1 223 ? 34.35300 17.55600 6.12300   1.000 28.87000 ? 227 ALA A HB1  1 
ATOM   3378 H HB2  . ALA A 1 223 ? 33.70200 16.39400 5.25900   1.000 28.87000 ? 227 ALA A HB2  1 
ATOM   3379 H HB3  . ALA A 1 223 ? 34.48200 17.57600 4.54000   1.000 28.87000 ? 227 ALA A HB3  1 
ATOM   3380 N N    . ASP A 1 224 ? 33.05700 20.37700 4.26600   1.000 20.06820 ? 228 ASP A N    1 
ATOM   3381 C CA   . ASP A 1 224 ? 33.38700 21.79300 4.36400   1.000 18.66276 ? 228 ASP A CA   1 
ATOM   3382 C C    . ASP A 1 224 ? 32.17000 22.70700 4.44600   1.000 19.28126 ? 228 ASP A C    1 
ATOM   3383 O O    . ASP A 1 224 ? 32.32800 23.92700 4.33700   1.000 20.87092 ? 228 ASP A O    1 
ATOM   3384 C CB   . ASP A 1 224 ? 34.30100 22.23000 3.21000   1.000 17.95215 ? 228 ASP A CB   1 
ATOM   3385 C CG   . ASP A 1 224 ? 33.63300 22.15300 1.86000   1.000 17.77318 ? 228 ASP A CG   1 
ATOM   3386 O OD1  . ASP A 1 224 ? 32.89200 21.18200 1.63400   1.000 17.17838 ? 228 ASP A OD1  1 
ATOM   3387 O OD2  . ASP A 1 224 ? 33.89200 23.04000 1.01300   1.000 18.91806 ? 228 ASP A OD2  1 
ATOM   3388 H H    . ASP A 1 224 ? 32.96200 20.08900 3.46100   1.000 24.09000 ? 228 ASP A H    1 
ATOM   3389 H HA   . ASP A 1 224 ? 33.88600 21.91000 5.18800   1.000 22.40000 ? 228 ASP A HA   1 
ATOM   3390 H HB2  . ASP A 1 224 ? 34.57300 23.14900 3.35500   1.000 21.55000 ? 228 ASP A HB2  1 
ATOM   3391 H HB3  . ASP A 1 224 ? 35.08000 21.65200 3.19000   1.000 21.55000 ? 228 ASP A HB3  1 
ATOM   3392 N N    . TRP A 1 225 ? 30.96700 22.15700 4.63900   1.000 17.94426 ? 229 TRP A N    1 
ATOM   3393 C CA   . TRP A 1 225 ? 29.76700 22.95600 4.85600   1.000 18.23113 ? 229 TRP A CA   1 
ATOM   3394 C C    . TRP A 1 225 ? 29.31900 22.88200 6.31300   1.000 19.66552 ? 229 TRP A C    1 
ATOM   3395 O O    . TRP A 1 225 ? 29.33900 21.81200 6.93500   1.000 21.86841 ? 229 TRP A O    1 
ATOM   3396 C CB   . TRP A 1 225 ? 28.58100 22.48300 4.01800   1.000 17.97058 ? 229 TRP A CB   1 
ATOM   3397 C CG   . TRP A 1 225 ? 28.78400 22.46700 2.53300   1.000 16.77043 ? 229 TRP A CG   1 
ATOM   3398 C CD1  . TRP A 1 225 ? 29.88900 22.86100 1.83100   1.000 16.79149 ? 229 TRP A CD1  1 
ATOM   3399 C CD2  . TRP A 1 225 ? 27.84000 22.01700 1.57200   1.000 17.27576 ? 229 TRP A CD2  1 
ATOM   3400 N NE1  . TRP A 1 225 ? 29.68400 22.68200 0.48300   1.000 16.92835 ? 229 TRP A NE1  1 
ATOM   3401 C CE2  . TRP A 1 225 ? 28.43200 22.15800 0.30200   1.000 17.30471 ? 229 TRP A CE2  1 
ATOM   3402 C CE3  . TRP A 1 225 ? 26.53300 21.50900 1.66100   1.000 18.92332 ? 229 TRP A CE3  1 
ATOM   3403 C CZ2  . TRP A 1 225 ? 27.77100 21.80600 -0.86300  1.000 19.54182 ? 229 TRP A CZ2  1 
ATOM   3404 C CZ3  . TRP A 1 225 ? 25.88300 21.15400 0.50600   1.000 20.37350 ? 229 TRP A CZ3  1 
ATOM   3405 C CH2  . TRP A 1 225 ? 26.50600 21.31100 -0.74700  1.000 20.19453 ? 229 TRP A CH2  1 
ATOM   3406 H H    . TRP A 1 225 ? 30.82400 21.30900 4.64800   1.000 21.54000 ? 229 TRP A H    1 
ATOM   3407 H HA   . TRP A 1 225 ? 29.99800 23.86600 4.61400   1.000 21.89000 ? 229 TRP A HA   1 
ATOM   3408 H HB2  . TRP A 1 225 ? 28.36300 21.57700 4.28600   1.000 21.57000 ? 229 TRP A HB2  1 
ATOM   3409 H HB3  . TRP A 1 225 ? 27.83100 23.07100 4.19700   1.000 21.57000 ? 229 TRP A HB3  1 
ATOM   3410 H HD1  . TRP A 1 225 ? 30.66800 23.20100 2.21000   1.000 20.16000 ? 229 TRP A HD1  1 
ATOM   3411 H HE1  . TRP A 1 225 ? 30.24600 22.86900 -0.14100  1.000 20.32000 ? 229 TRP A HE1  1 
ATOM   3412 H HE3  . TRP A 1 225 ? 26.11700 21.41500 2.48700   1.000 22.72000 ? 229 TRP A HE3  1 
ATOM   3413 H HZ2  . TRP A 1 225 ? 28.17600 21.90300 -1.69500  1.000 23.46000 ? 229 TRP A HZ2  1 
ATOM   3414 H HZ3  . TRP A 1 225 ? 25.02200 20.80700 0.55200   1.000 24.46000 ? 229 TRP A HZ3  1 
ATOM   3415 H HH2  . TRP A 1 225 ? 26.04200 21.07000 -1.51600  1.000 24.24000 ? 229 TRP A HH2  1 
ATOM   3416 N N    . ALA A 1 226 ? 28.86900 24.00500 6.83900   1.000 18.27588 ? 230 ALA A N    1 
ATOM   3417 C CA   . ALA A 1 226 ? 28.29400 24.01100 8.18000   1.000 16.40986 ? 230 ALA A CA   1 
ATOM   3418 C C    . ALA A 1 226 ? 26.89400 23.40000 8.15600   1.000 15.73610 ? 230 ALA A C    1 
ATOM   3419 O O    . ALA A 1 226 ? 26.13800 23.54000 7.18300   1.000 15.77558 ? 230 ALA A O    1 
ATOM   3420 C CB   . ALA A 1 226 ? 28.23200 25.43600 8.71900   1.000 16.65726 ? 230 ALA A CB   1 
ATOM   3421 H H    . ALA A 1 226 ? 28.88200 24.77100 6.44900   1.000 21.94000 ? 230 ALA A H    1 
ATOM   3422 H HA   . ALA A 1 226 ? 28.84600 23.48500 8.77900   1.000 19.70000 ? 230 ALA A HA   1 
ATOM   3423 H HB1  . ALA A 1 226 ? 27.83900 25.42100 9.60600   1.000 20.00000 ? 230 ALA A HB1  1 
ATOM   3424 H HB2  . ALA A 1 226 ? 29.13200 25.79600 8.76200   1.000 20.00000 ? 230 ALA A HB2  1 
ATOM   3425 H HB3  . ALA A 1 226 ? 27.68800 25.97500 8.12500   1.000 20.00000 ? 230 ALA A HB3  1 
ATOM   3426 N N    . VAL A 1 227 ? 26.54100 22.73000 9.25100   1.000 15.20972 ? 231 VAL A N    1 
ATOM   3427 C CA   A VAL A 1 227 ? 25.23200 22.11200 9.37300   0.510 15.02549 ? 231 VAL A CA   1 
ATOM   3428 C CA   B VAL A 1 227 ? 25.25200 22.04800 9.38000   0.490 15.34658 ? 231 VAL A CA   1 
ATOM   3429 C C    . VAL A 1 227 ? 24.86200 22.02300 10.84900  1.000 14.04905 ? 231 VAL A C    1 
ATOM   3430 O O    . VAL A 1 227 ? 25.70700 21.75200 11.71400  1.000 15.39132 ? 231 VAL A O    1 
ATOM   3431 C CB   A VAL A 1 227 ? 25.20700 20.74100 8.66200   0.510 16.02824 ? 231 VAL A CB   1 
ATOM   3432 C CB   B VAL A 1 227 ? 25.30900 20.57200 8.93200   0.490 16.92045 ? 231 VAL A CB   1 
ATOM   3433 C CG1  A VAL A 1 227 ? 26.47200 19.95500 8.99500   0.510 15.65714 ? 231 VAL A CG1  1 
ATOM   3434 C CG1  B VAL A 1 227 ? 23.95800 19.88900 9.16800   0.490 18.17060 ? 231 VAL A CG1  1 
ATOM   3435 C CG2  A VAL A 1 227 ? 23.95500 19.96000 9.00600   0.510 16.78886 ? 231 VAL A CG2  1 
ATOM   3436 C CG2  B VAL A 1 227 ? 25.70800 20.42500 7.49800   0.490 17.06784 ? 231 VAL A CG2  1 
ATOM   3437 H H    A VAL A 1 227 ? 27.04700 22.62100 9.93800   0.510 18.26000 ? 231 VAL A H    1 
ATOM   3438 H H    B VAL A 1 227 ? 27.04000 22.65300 9.94800   0.490 18.26000 ? 231 VAL A H    1 
ATOM   3439 H HA   A VAL A 1 227 ? 24.56100 22.67500 8.95600   0.510 18.04000 ? 231 VAL A HA   1 
ATOM   3440 H HA   B VAL A 1 227 ? 24.62100 22.55000 8.84100   0.490 18.42000 ? 231 VAL A HA   1 
ATOM   3441 H HB   A VAL A 1 227 ? 25.18700 20.88600 7.70300   0.510 19.24000 ? 231 VAL A HB   1 
ATOM   3442 H HB   B VAL A 1 227 ? 25.99100 20.13600 9.46700   0.490 20.31000 ? 231 VAL A HB   1 
ATOM   3443 H HG11 A VAL A 1 227 ? 26.35900 19.03700 8.70400   0.510 18.79000 ? 231 VAL A HG11 1 
ATOM   3444 H HG11 B VAL A 1 227 ? 23.92800 19.06400 8.65700   0.490 21.81000 ? 231 VAL A HG11 1 
ATOM   3445 H HG12 A VAL A 1 227 ? 27.22500 20.35800 8.53400   0.510 18.79000 ? 231 VAL A HG12 1 
ATOM   3446 H HG12 B VAL A 1 227 ? 23.86300 19.69600 10.11400  0.490 21.81000 ? 231 VAL A HG12 1 
ATOM   3447 H HG13 A VAL A 1 227 ? 26.61800 19.98300 9.95300   0.510 18.79000 ? 231 VAL A HG13 1 
ATOM   3448 H HG13 B VAL A 1 227 ? 23.24900 20.48300 8.87800   0.490 21.81000 ? 231 VAL A HG13 1 
ATOM   3449 H HG21 A VAL A 1 227 ? 23.87900 19.20300 8.40300   0.510 20.15000 ? 231 VAL A HG21 1 
ATOM   3450 H HG21 B VAL A 1 227 ? 25.71800 19.48300 7.26800   0.490 20.49000 ? 231 VAL A HG21 1 
ATOM   3451 H HG22 A VAL A 1 227 ? 24.01900 19.64700 9.92200   0.510 20.15000 ? 231 VAL A HG22 1 
ATOM   3452 H HG22 B VAL A 1 227 ? 25.06600 20.89500 6.94200   0.490 20.49000 ? 231 VAL A HG22 1 
ATOM   3453 H HG23 A VAL A 1 227 ? 23.18300 20.54000 8.90800   0.510 20.15000 ? 231 VAL A HG23 1 
ATOM   3454 H HG23 B VAL A 1 227 ? 26.59200 20.80500 7.37500   0.490 20.49000 ? 231 VAL A HG23 1 
ATOM   3455 N N    . GLY A 1 228 ? 23.59500 22.27000 11.12500  1.000 13.52267 ? 232 GLY A N    1 
ATOM   3456 C CA   . GLY A 1 228 ? 23.03700 22.01700 12.43900  1.000 13.96483 ? 232 GLY A CA   1 
ATOM   3457 C C    . GLY A 1 228 ? 21.78800 21.17900 12.25100  1.000 12.27516 ? 232 GLY A C    1 
ATOM   3458 O O    . GLY A 1 228 ? 21.07700 21.31900 11.26100  1.000 13.47793 ? 232 GLY A O    1 
ATOM   3459 H H    . GLY A 1 228 ? 23.03000 22.59000 10.56100  1.000 16.24000 ? 232 GLY A H    1 
ATOM   3460 H HA2  . GLY A 1 228 ? 23.67300 21.53400 12.99000  1.000 16.76000 ? 232 GLY A HA2  1 
ATOM   3461 H HA3  . GLY A 1 228 ? 22.80700 22.85100 12.87800  1.000 16.76000 ? 232 GLY A HA3  1 
ATOM   3462 N N    . ASP A 1 229 ? 21.53300 20.28100 13.19100  1.000 12.21725 ? 233 ASP A N    1 
ATOM   3463 C CA   . ASP A 1 229 ? 20.38800 19.37900 13.05000  1.000 11.82247 ? 233 ASP A CA   1 
ATOM   3464 C C    . ASP A 1 229 ? 19.86000 18.92500 14.41000  1.000 12.41728 ? 233 ASP A C    1 
ATOM   3465 O O    . ASP A 1 229 ? 20.52800 19.05700 15.45100  1.000 12.81206 ? 233 ASP A O    1 
ATOM   3466 C CB   . ASP A 1 229 ? 20.73000 18.12800 12.20300  1.000 12.44886 ? 233 ASP A CB   1 
ATOM   3467 C CG   . ASP A 1 229 ? 21.43200 17.04800 13.02900  1.000 12.25673 ? 233 ASP A CG   1 
ATOM   3468 O OD1  . ASP A 1 229 ? 22.54100 17.30500 13.54000  1.000 12.47781 ? 233 ASP A OD1  1 
ATOM   3469 O OD2  . ASP A 1 229 ? 20.84400 15.95000 13.20700  1.000 12.46465 ? 233 ASP A OD2  1 
ATOM   3470 H H    . ASP A 1 229 ? 21.99700 20.17300 13.90700  1.000 14.67000 ? 233 ASP A H    1 
ATOM   3471 H HA   . ASP A 1 229 ? 19.69200 19.89700 12.61500  1.000 14.19000 ? 233 ASP A HA   1 
ATOM   3472 H HB2  . ASP A 1 229 ? 19.91100 17.75100 11.84600  1.000 14.95000 ? 233 ASP A HB2  1 
ATOM   3473 H HB3  . ASP A 1 229 ? 21.32000 18.38600 11.47800  1.000 14.95000 ? 233 ASP A HB3  1 
ATOM   3474 N N    . LYS A 1 230 ? 18.66300 18.34100 14.37000  1.000 11.71456 ? 234 LYS A N    1 
ATOM   3475 C CA   . LYS A 1 230 ? 18.11700 17.60000 15.50500  1.000 11.49875 ? 234 LYS A CA   1 
ATOM   3476 C C    . LYS A 1 230 ? 17.44600 16.33400 14.99300  1.000 11.58034 ? 234 LYS A C    1 
ATOM   3477 O O    . LYS A 1 230 ? 16.62000 16.39000 14.07300  1.000 11.66192 ? 234 LYS A O    1 
ATOM   3478 C CB   . LYS A 1 230 ? 17.07700 18.41700 16.28300  1.000 11.22240 ? 234 LYS A CB   1 
ATOM   3479 C CG   . LYS A 1 230 ? 16.42200 17.64000 17.44600  1.000 11.66719 ? 234 LYS A CG   1 
ATOM   3480 C CD   . LYS A 1 230 ? 17.38000 17.52700 18.65400  1.000 12.52519 ? 234 LYS A CD   1 
ATOM   3481 C CE   . LYS A 1 230 ? 16.88700 16.44300 19.63300  1.000 12.50939 ? 234 LYS A CE   1 
ATOM   3482 N NZ   . LYS A 1 230 ? 17.30500 15.07700 19.26100  1.000 12.93050 ? 234 LYS A NZ   1 
ATOM   3483 H H    . LYS A 1 230 ? 18.14100 18.36000 13.68700  1.000 14.06000 ? 234 LYS A H    1 
ATOM   3484 H HA   . LYS A 1 230 ? 18.84700 17.37100 16.10100  1.000 13.81000 ? 234 LYS A HA   1 
ATOM   3485 H HB2  . LYS A 1 230 ? 17.51200 19.20000 16.65700  1.000 13.47000 ? 234 LYS A HB2  1 
ATOM   3486 H HB3  . LYS A 1 230 ? 16.37300 18.68800 15.67400  1.000 13.47000 ? 234 LYS A HB3  1 
ATOM   3487 H HG2  . LYS A 1 230 ? 15.62100 18.10600 17.73400  1.000 14.01000 ? 234 LYS A HG2  1 
ATOM   3488 H HG3  . LYS A 1 230 ? 16.19700 16.74500 17.14900  1.000 14.01000 ? 234 LYS A HG3  1 
ATOM   3489 H HD2  . LYS A 1 230 ? 18.26600 17.28300 18.34500  1.000 15.04000 ? 234 LYS A HD2  1 
ATOM   3490 H HD3  . LYS A 1 230 ? 17.41400 18.37500 19.12300  1.000 15.04000 ? 234 LYS A HD3  1 
ATOM   3491 H HE2  . LYS A 1 230 ? 17.24400 16.63200 20.51500  1.000 15.02000 ? 234 LYS A HE2  1 
ATOM   3492 H HE3  . LYS A 1 230 ? 15.91800 16.46000 19.65700  1.000 15.02000 ? 234 LYS A HE3  1 
ATOM   3493 H HZ1  . LYS A 1 230 ? 16.75800 14.48000 19.63000  1.000 15.53000 ? 234 LYS A HZ1  1 
ATOM   3494 H HZ2  . LYS A 1 230 ? 17.28200 14.98200 18.37600  1.000 15.53000 ? 234 LYS A HZ2  1 
ATOM   3495 H HZ3  . LYS A 1 230 ? 18.13400 14.92400 19.54600  1.000 15.53000 ? 234 LYS A HZ3  1 
ATOM   3496 N N    . THR A 1 231 ? 17.75600 15.20800 15.61600  1.000 11.99354 ? 235 THR A N    1 
ATOM   3497 C CA   . THR A 1 231 ? 17.24300 13.90200 15.25400  1.000 12.04092 ? 235 THR A CA   1 
ATOM   3498 C C    . THR A 1 231 ? 16.04700 13.47300 16.11400  1.000 12.21989 ? 235 THR A C    1 
ATOM   3499 O O    . THR A 1 231 ? 15.77700 13.99900 17.20700  1.000 11.60139 ? 235 THR A O    1 
ATOM   3500 C CB   . THR A 1 231 ? 18.33400 12.85000 15.43600  1.000 12.89891 ? 235 THR A CB   1 
ATOM   3501 O OG1  . THR A 1 231 ? 18.84100 12.91500 16.78200  1.000 14.09643 ? 235 THR A OG1  1 
ATOM   3502 C CG2  . THR A 1 231 ? 19.49400 13.12000 14.49700  1.000 12.83049 ? 235 THR A CG2  1 
ATOM   3503 H H    . THR A 1 231 ? 18.29200 15.17600 16.28800  1.000 14.40000 ? 235 THR A H    1 
ATOM   3504 H HA   . THR A 1 231 ? 16.95200 13.95900 14.33000  1.000 14.46000 ? 235 THR A HA   1 
ATOM   3505 H HB   . THR A 1 231 ? 17.96300 11.97300 15.25100  1.000 15.49000 ? 235 THR A HB   1 
ATOM   3506 H HG1  . THR A 1 231 ? 18.20400 12.92900 17.32900  1.000 16.92000 ? 235 THR A HG1  1 
ATOM   3507 H HG21 . THR A 1 231 ? 20.17300 12.43600 14.60300  1.000 15.40000 ? 235 THR A HG21 1 
ATOM   3508 H HG22 . THR A 1 231 ? 19.18400 13.11500 13.57800  1.000 15.40000 ? 235 THR A HG22 1 
ATOM   3509 H HG23 . THR A 1 231 ? 19.88500 13.98500 14.69300  1.000 15.40000 ? 235 THR A HG23 1 
ATOM   3510 N N    . GLY A 1 232 ? 15.38100 12.41500 15.64500  1.000 11.34347 ? 236 GLY A N    1 
ATOM   3511 C CA   . GLY A 1 232 ? 14.38300 11.70700 16.41200  1.000 12.64625 ? 236 GLY A CA   1 
ATOM   3512 C C    . GLY A 1 232 ? 14.33100 10.25000 16.03100  1.000 12.71731 ? 236 GLY A C    1 
ATOM   3513 O O    . GLY A 1 232 ? 14.49900 9.91000  14.85500  1.000 12.53571 ? 236 GLY A O    1 
ATOM   3514 H H    . GLY A 1 232 ? 15.49900 12.08600 14.85900  1.000 13.62000 ? 236 GLY A H    1 
ATOM   3515 H HA2  . GLY A 1 232 ? 14.59200 11.77300 17.35700  1.000 15.18000 ? 236 GLY A HA2  1 
ATOM   3516 H HA3  . GLY A 1 232 ? 13.51100 12.10100 16.25400  1.000 15.18000 ? 236 GLY A HA3  1 
ATOM   3517 N N    . THR A 1 233 ? 14.10300 9.38100  17.01200  1.000 12.21725 ? 237 THR A N    1 
ATOM   3518 C CA   . THR A 1 233 ? 14.03500 7.94400  16.78300  1.000 14.53069 ? 237 THR A CA   1 
ATOM   3519 C C    . THR A 1 233 ? 13.01800 7.38300  17.76700  1.000 13.67006 ? 237 THR A C    1 
ATOM   3520 O O    . THR A 1 233 ? 13.31500 7.26600  18.95400  1.000 13.73849 ? 237 THR A O    1 
ATOM   3521 C CB   . THR A 1 233 ? 15.39100 7.29100  16.99700  1.000 16.85465 ? 237 THR A CB   1 
ATOM   3522 O OG1  . THR A 1 233 ? 16.39800 7.99500  16.26600  1.000 17.47315 ? 237 THR A OG1  1 
ATOM   3523 C CG2  . THR A 1 233 ? 15.32800 5.81300  16.58700  1.000 18.64960 ? 237 THR A CG2  1 
ATOM   3524 H H    . THR A 1 233 ? 13.98200 9.60500  17.83400  1.000 14.67000 ? 237 THR A H    1 
ATOM   3525 H HA   . THR A 1 233 ? 13.74400 7.76900  15.87500  1.000 17.45000 ? 237 THR A HA   1 
ATOM   3526 H HB   . THR A 1 233 ? 15.63800 7.32400  17.93400  1.000 20.23000 ? 237 THR A HB   1 
ATOM   3527 H HG1  . THR A 1 233 ? 17.16000 7.72600  16.49500  1.000 20.97000 ? 237 THR A HG1  1 
ATOM   3528 H HG21 . THR A 1 233 ? 16.13800 5.56500  16.11500  1.000 22.39000 ? 237 THR A HG21 1 
ATOM   3529 H HG22 . THR A 1 233 ? 15.23800 5.25400  17.37500  1.000 22.39000 ? 237 THR A HG22 1 
ATOM   3530 H HG23 . THR A 1 233 ? 14.56600 5.66300  16.00600  1.000 22.39000 ? 237 THR A HG23 1 
ATOM   3531 N N    . CYS A 1 234 ? 11.82100 7.04100  17.28900  1.000 13.37266 ? 238 CYS A N    1 
ATOM   3532 C CA   . CYS A 1 234 ? 10.77700 6.60800  18.21500  1.000 13.63848 ? 238 CYS A CA   1 
ATOM   3533 C C    . CYS A 1 234 ? 10.98900 5.18800  18.73500  1.000 15.76505 ? 238 CYS A C    1 
ATOM   3534 O O    . CYS A 1 234 ? 10.52100 4.86500  19.84200  1.000 17.45736 ? 238 CYS A O    1 
ATOM   3535 C CB   . CYS A 1 234 ? 9.39200  6.70700  17.56300  1.000 13.69901 ? 238 CYS A CB   1 
ATOM   3536 S SG   . CYS A 1 234 ? 8.56800  8.30400  17.62100  1.000 12.74890 ? 238 CYS A SG   1 
ATOM   3537 H H    . CYS A 1 234 ? 11.59500 7.05000  16.46000  1.000 16.05000 ? 238 CYS A H    1 
ATOM   3538 H HA   . CYS A 1 234 ? 10.80000 7.21100  18.97400  1.000 16.38000 ? 238 CYS A HA   1 
ATOM   3539 H HB2  . CYS A 1 234 ? 9.48600  6.47200  16.62700  1.000 16.45000 ? 238 CYS A HB2  1 
ATOM   3540 H HB3  . CYS A 1 234 ? 8.80800  6.07200  18.00700  1.000 16.45000 ? 238 CYS A HB3  1 
ATOM   3541 N N    . GLY A 1 235 ? 11.64500 4.32700  17.97100  1.000 16.69411 ? 239 GLY A N    1 
ATOM   3542 C CA   . GLY A 1 235 ? 11.92300 2.97000  18.40900  1.000 17.87320 ? 239 GLY A CA   1 
ATOM   3543 C C    . GLY A 1 235 ? 10.93200 1.92800  17.95700  1.000 16.84676 ? 239 GLY A C    1 
ATOM   3544 O O    . GLY A 1 235 ? 11.09800 0.74800  18.29500  1.000 17.36524 ? 239 GLY A O    1 
ATOM   3545 H H    . GLY A 1 235 ? 11.94300 4.50800  17.18400  1.000 20.04000 ? 239 GLY A H    1 
ATOM   3546 H HA2  . GLY A 1 235 ? 12.79500 2.71000  18.07400  1.000 21.45000 ? 239 GLY A HA2  1 
ATOM   3547 H HA3  . GLY A 1 235 ? 11.94000 2.95700  19.37900  1.000 21.45000 ? 239 GLY A HA3  1 
ATOM   3548 N N    . VAL A 1 236 ? 9.91200  2.33100  17.19800  1.000 14.12538 ? 240 VAL A N    1 
ATOM   3549 C CA   . VAL A 1 236 ? 8.85300  1.46100  16.70900  1.000 13.72796 ? 240 VAL A CA   1 
ATOM   3550 C C    . VAL A 1 236 ? 8.39700  2.02000  15.37400  1.000 13.00945 ? 240 VAL A C    1 
ATOM   3551 O O    . VAL A 1 236 ? 8.63900  3.18400  15.05100  1.000 13.38055 ? 240 VAL A O    1 
ATOM   3552 C CB   . VAL A 1 236 ? 7.65500  1.42900  17.69600  1.000 15.07812 ? 240 VAL A CB   1 
ATOM   3553 C CG1  . VAL A 1 236 ? 7.97400  0.60400  18.93500  1.000 16.19668 ? 240 VAL A CG1  1 
ATOM   3554 C CG2  . VAL A 1 236 ? 7.22400  2.85200  18.08100  1.000 15.53607 ? 240 VAL A CG2  1 
ATOM   3555 H H    . VAL A 1 236 ? 9.80900  3.14600  16.94300  1.000 16.96000 ? 240 VAL A H    1 
ATOM   3556 H HA   . VAL A 1 236 ? 9.18600  0.55900  16.58600  1.000 16.48000 ? 240 VAL A HA   1 
ATOM   3557 H HB   . VAL A 1 236 ? 6.90900  1.00100  17.24800  1.000 18.10000 ? 240 VAL A HB   1 
ATOM   3558 H HG11 . VAL A 1 236 ? 7.19400  0.58800  19.51300  1.000 19.44000 ? 240 VAL A HG11 1 
ATOM   3559 H HG12 . VAL A 1 236 ? 8.20300  -0.29800 18.66300  1.000 19.44000 ? 240 VAL A HG12 1 
ATOM   3560 H HG13 . VAL A 1 236 ? 8.72200  1.01000  19.40100  1.000 19.44000 ? 240 VAL A HG13 1 
ATOM   3561 H HG21 . VAL A 1 236 ? 6.42700  2.80200  18.63100  1.000 18.65000 ? 240 VAL A HG21 1 
ATOM   3562 H HG22 . VAL A 1 236 ? 7.94200  3.27600  18.57700  1.000 18.65000 ? 240 VAL A HG22 1 
ATOM   3563 H HG23 . VAL A 1 236 ? 7.03800  3.35500  17.27300  1.000 18.65000 ? 240 VAL A HG23 1 
ATOM   3564 N N    . TYR A 1 237 ? 7.72100  1.17600  14.60500  1.000 12.34359 ? 241 TYR A N    1 
ATOM   3565 C CA   . TYR A 1 237 ? 7.01600  1.59300  13.38700  1.000 11.91722 ? 241 TYR A CA   1 
ATOM   3566 C C    . TYR A 1 237 ? 7.95300  2.27800  12.39400  1.000 11.82510 ? 241 TYR A C    1 
ATOM   3567 O O    . TYR A 1 237 ? 7.57400  3.24000  11.71300  1.000 11.46190 ? 241 TYR A O    1 
ATOM   3568 C CB   . TYR A 1 237 ? 5.77500  2.47100  13.68200  1.000 11.89353 ? 241 TYR A CB   1 
ATOM   3569 C CG   . TYR A 1 237 ? 4.64600  1.69800  14.33900  1.000 12.00670 ? 241 TYR A CG   1 
ATOM   3570 C CD1  . TYR A 1 237 ? 3.85200  0.82600  13.60500  1.000 11.92775 ? 241 TYR A CD1  1 
ATOM   3571 C CD2  . TYR A 1 237 ? 4.39000  1.81500  15.71000  1.000 12.70415 ? 241 TYR A CD2  1 
ATOM   3572 C CE1  . TYR A 1 237 ? 2.84900  0.08400  14.19300  1.000 13.25685 ? 241 TYR A CE1  1 
ATOM   3573 C CE2  . TYR A 1 237 ? 3.38600  1.07500  16.30900  1.000 13.70691 ? 241 TYR A CE2  1 
ATOM   3574 C CZ   . TYR A 1 237 ? 2.60900  0.22600  15.54600  1.000 13.97799 ? 241 TYR A CZ   1 
ATOM   3575 O OH   . TYR A 1 237 ? 1.61300  -0.54100 16.09400  1.000 15.21235 ? 241 TYR A OH   1 
ATOM   3576 H H    . TYR A 1 237 ? 7.65000  0.33400  14.76700  1.000 14.82000 ? 241 TYR A H    1 
ATOM   3577 H HA   . TYR A 1 237 ? 6.69000  0.78400  12.96200  1.000 14.31000 ? 241 TYR A HA   1 
ATOM   3578 H HB2  . TYR A 1 237 ? 6.03300  3.19000  14.28100  1.000 14.28000 ? 241 TYR A HB2  1 
ATOM   3579 H HB3  . TYR A 1 237 ? 5.44200  2.83700  12.84800  1.000 14.28000 ? 241 TYR A HB3  1 
ATOM   3580 H HD1  . TYR A 1 237 ? 4.00200  0.74000  12.69100  1.000 14.32000 ? 241 TYR A HD1  1 
ATOM   3581 H HD2  . TYR A 1 237 ? 4.90100  2.39700  16.22500  1.000 15.25000 ? 241 TYR A HD2  1 
ATOM   3582 H HE1  . TYR A 1 237 ? 2.34100  -0.50500 13.68400  1.000 15.92000 ? 241 TYR A HE1  1 
ATOM   3583 H HE2  . TYR A 1 237 ? 3.23400  1.15000  17.22300  1.000 16.45000 ? 241 TYR A HE2  1 
ATOM   3584 H HH   . TYR A 1 237 ? 1.53500  -0.36900 16.91300  1.000 18.26000 ? 241 TYR A HH   1 
ATOM   3585 N N    . GLY A 1 238 ? 9.19200  1.80200  12.33700  1.000 13.15421 ? 242 GLY A N    1 
ATOM   3586 C CA   . GLY A 1 238 ? 10.16600 2.34400  11.40200  1.000 12.93839 ? 242 GLY A CA   1 
ATOM   3587 C C    . GLY A 1 238 ? 10.27100 3.85600  11.44100  1.000 11.69088 ? 242 GLY A C    1 
ATOM   3588 O O    . GLY A 1 238 ? 10.57600 4.48300  10.42500  1.000 12.46992 ? 242 GLY A O    1 
ATOM   3589 H H    . GLY A 1 238 ? 9.49200  1.16400  12.82900  1.000 15.79000 ? 242 GLY A H    1 
ATOM   3590 H HA2  . GLY A 1 238 ? 11.04000 1.97700  11.60900  1.000 15.53000 ? 242 GLY A HA2  1 
ATOM   3591 H HA3  . GLY A 1 238 ? 9.91900  2.08300  10.50100  1.000 15.53000 ? 242 GLY A HA3  1 
ATOM   3592 N N    . THR A 1 239 ? 10.06200 4.47500  12.61300  1.000 11.23819 ? 243 THR A N    1 
ATOM   3593 C CA   . THR A 1 239 ? 9.83700  5.90800  12.71200  1.000 11.84616 ? 243 THR A CA   1 
ATOM   3594 C C    . THR A 1 239 ? 11.07600 6.59700  13.24900  1.000 12.41991 ? 243 THR A C    1 
ATOM   3595 O O    . THR A 1 239 ? 11.47200 6.37700  14.39900  1.000 12.91471 ? 243 THR A O    1 
ATOM   3596 C CB   . THR A 1 239 ? 8.61800  6.18200  13.60000  1.000 10.83551 ? 243 THR A CB   1 
ATOM   3597 O OG1  . THR A 1 239 ? 7.44100  5.67300  12.95300  1.000 12.12777 ? 243 THR A OG1  1 
ATOM   3598 C CG2  . THR A 1 239 ? 8.39600  7.62600  13.78200  1.000 11.51191 ? 243 THR A CG2  1 
ATOM   3599 H H    . THR A 1 239 ? 10.04900 4.07100  13.37200  1.000 13.49000 ? 243 THR A H    1 
ATOM   3600 H HA   . THR A 1 239 ? 9.68100  6.26500  11.82300  1.000 14.22000 ? 243 THR A HA   1 
ATOM   3601 H HB   . THR A 1 239 ? 8.77200  5.76400  14.46100  1.000 13.01000 ? 243 THR A HB   1 
ATOM   3602 H HG1  . THR A 1 239 ? 7.49900  4.83900  12.86600  1.000 14.56000 ? 243 THR A HG1  1 
ATOM   3603 H HG21 . THR A 1 239 ? 7.58800  7.77400  14.29900  1.000 13.82000 ? 243 THR A HG21 1 
ATOM   3604 H HG22 . THR A 1 239 ? 9.14700  8.02000  14.25200  1.000 13.82000 ? 243 THR A HG22 1 
ATOM   3605 H HG23 . THR A 1 239 ? 8.30100  8.05900  12.91900  1.000 13.82000 ? 243 THR A HG23 1 
ATOM   3606 N N    . ALA A 1 240 ? 11.67900 7.41800  12.40400  1.000 12.18041 ? 244 ALA A N    1 
ATOM   3607 C CA   . ALA A 1 240 ? 12.84700 8.20600  12.76600  1.000 12.04355 ? 244 ALA A CA   1 
ATOM   3608 C C    . ALA A 1 240 ? 12.92400 9.39000  11.81800  1.000 11.35662 ? 244 ALA A C    1 
ATOM   3609 O O    . ALA A 1 240 ? 12.25800 9.41000  10.77700  1.000 11.56191 ? 244 ALA A O    1 
ATOM   3610 C CB   . ALA A 1 240 ? 14.13500 7.37100  12.70700  1.000 12.58046 ? 244 ALA A CB   1 
ATOM   3611 H H    . ALA A 1 240 ? 11.42400 7.54100  11.59200  1.000 14.63000 ? 244 ALA A H    1 
ATOM   3612 H HA   . ALA A 1 240 ? 12.74500 8.53500  13.67300  1.000 14.46000 ? 244 ALA A HA   1 
ATOM   3613 H HB1  . ALA A 1 240 ? 14.88500 7.92800  12.96900  1.000 15.11000 ? 244 ALA A HB1  1 
ATOM   3614 H HB2  . ALA A 1 240 ? 14.05300 6.62000  13.31600  1.000 15.11000 ? 244 ALA A HB2  1 
ATOM   3615 H HB3  . ALA A 1 240 ? 14.26200 7.05000  11.80100  1.000 15.11000 ? 244 ALA A HB3  1 
ATOM   3616 N N    . ASN A 1 241 ? 13.74700 10.37300 12.17900  1.000 11.09607 ? 245 ASN A N    1 
ATOM   3617 C CA   . ASN A 1 241 ? 13.72100 11.63600 11.45600  1.000 11.04606 ? 245 ASN A CA   1 
ATOM   3618 C C    . ASN A 1 241 ? 14.97200 12.45200 11.77000  1.000 11.43032 ? 245 ASN A C    1 
ATOM   3619 O O    . ASN A 1 241 ? 15.76700 12.11200 12.65700  1.000 11.25924 ? 245 ASN A O    1 
ATOM   3620 C CB   . ASN A 1 241 ? 12.42900 12.39700 11.77200  1.000 11.02501 ? 245 ASN A CB   1 
ATOM   3621 C CG   . ASN A 1 241 ? 12.24900 12.59000 13.25300  1.000 11.59613 ? 245 ASN A CG   1 
ATOM   3622 O OD1  . ASN A 1 241 ? 13.06000 13.22900 13.92100  1.000 12.68310 ? 245 ASN A OD1  1 
ATOM   3623 N ND2  . ASN A 1 241 ? 11.20100 11.97800 13.79500  1.000 12.31990 ? 245 ASN A ND2  1 
ATOM   3624 H H    . ASN A 1 241 ? 14.31300 10.33200 12.82500  1.000 13.32000 ? 245 ASN A H    1 
ATOM   3625 H HA   . ASN A 1 241 ? 13.75800 11.46300 10.50200  1.000 13.27000 ? 245 ASN A HA   1 
ATOM   3626 H HB2  . ASN A 1 241 ? 12.46000 13.27000 11.35200  1.000 13.24000 ? 245 ASN A HB2  1 
ATOM   3627 H HB3  . ASN A 1 241 ? 11.67100 11.89400 11.43500  1.000 13.24000 ? 245 ASN A HB3  1 
ATOM   3628 H HD21 . ASN A 1 241 ? 11.04800 12.05200 14.63800  1.000 14.79000 ? 245 ASN A HD21 1 
ATOM   3629 H HD22 . ASN A 1 241 ? 10.67600 11.50800 13.30200  1.000 14.79000 ? 245 ASN A HD22 1 
ATOM   3630 N N    . ASP A 1 242 ? 15.12700 13.53900 11.01900  1.000 10.98553 ? 246 ASP A N    1 
ATOM   3631 C CA   . ASP A 1 242 ? 16.16100 14.54100 11.20100  1.000 11.76720 ? 246 ASP A CA   1 
ATOM   3632 C C    . ASP A 1 242 ? 15.70600 15.79700 10.47100  1.000 12.03565 ? 246 ASP A C    1 
ATOM   3633 O O    . ASP A 1 242 ? 15.09300 15.71800 9.39600   1.000 12.78838 ? 246 ASP A O    1 
ATOM   3634 C CB   . ASP A 1 242 ? 17.46800 13.99200 10.60900  1.000 11.90143 ? 246 ASP A CB   1 
ATOM   3635 C CG   . ASP A 1 242 ? 18.72000 14.74300 11.04600  1.000 12.34622 ? 246 ASP A CG   1 
ATOM   3636 O OD1  . ASP A 1 242 ? 18.67600 15.39800 12.10700  1.000 12.27252 ? 246 ASP A OD1  1 
ATOM   3637 O OD2  . ASP A 1 242 ? 19.72700 14.67000 10.32100  1.000 12.03039 ? 246 ASP A OD2  1 
ATOM   3638 H H    . ASP A 1 242 ? 14.61100 13.72800 10.35700  1.000 13.19000 ? 246 ASP A H    1 
ATOM   3639 H HA   . ASP A 1 242 ? 16.30300 14.77400 12.13200  1.000 14.13000 ? 246 ASP A HA   1 
ATOM   3640 H HB2  . ASP A 1 242 ? 17.56900 13.06800 10.88600  1.000 14.29000 ? 246 ASP A HB2  1 
ATOM   3641 H HB3  . ASP A 1 242 ? 17.41700 14.04600 9.64200   1.000 14.29000 ? 246 ASP A HB3  1 
ATOM   3642 N N    . TYR A 1 243 ? 15.98000 16.94800 11.05600  1.000 12.06724 ? 247 TYR A N    1 
ATOM   3643 C CA   . TYR A 1 243 ? 15.84000 18.22100 10.35800  1.000 12.14356 ? 247 TYR A CA   1 
ATOM   3644 C C    . TYR A 1 243 ? 17.10900 19.03400 10.53700  1.000 11.74088 ? 247 TYR A C    1 
ATOM   3645 O O    . TYR A 1 243 ? 17.83300 18.85700 11.52300  1.000 11.94091 ? 247 TYR A O    1 
ATOM   3646 C CB   . TYR A 1 243 ? 14.59300 19.01100 10.76400  1.000 11.72772 ? 247 TYR A CB   1 
ATOM   3647 C CG   . TYR A 1 243 ? 14.41000 19.33300 12.24100  1.000 11.93564 ? 247 TYR A CG   1 
ATOM   3648 C CD1  . TYR A 1 243 ? 15.18700 20.29100 12.86200  1.000 12.01197 ? 247 TYR A CD1  1 
ATOM   3649 C CD2  . TYR A 1 243 ? 13.41900 18.70800 12.98300  1.000 11.70140 ? 247 TYR A CD2  1 
ATOM   3650 C CE1  . TYR A 1 243 ? 14.98500 20.60800 14.20500  1.000 11.77246 ? 247 TYR A CE1  1 
ATOM   3651 C CE2  . TYR A 1 243 ? 13.19800 19.03300 14.30300  1.000 11.65403 ? 247 TYR A CE2  1 
ATOM   3652 C CZ   . TYR A 1 243 ? 13.99800 19.97100 14.90700  1.000 12.06197 ? 247 TYR A CZ   1 
ATOM   3653 O OH   . TYR A 1 243 ? 13.80700 20.29200 16.24100  1.000 12.35674 ? 247 TYR A OH   1 
ATOM   3654 H H    . TYR A 1 243 ? 16.25300 17.02400 11.86800  1.000 14.49000 ? 247 TYR A H    1 
ATOM   3655 H HA   . TYR A 1 243 ? 15.73200 18.05000 9.40900   1.000 14.58000 ? 247 TYR A HA   1 
ATOM   3656 H HB2  . TYR A 1 243 ? 14.61300 19.85900 10.29400  1.000 14.08000 ? 247 TYR A HB2  1 
ATOM   3657 H HB3  . TYR A 1 243 ? 13.81500 18.49900 10.49200  1.000 14.08000 ? 247 TYR A HB3  1 
ATOM   3658 H HD1  . TYR A 1 243 ? 15.85000 20.73000 12.38000  1.000 14.42000 ? 247 TYR A HD1  1 
ATOM   3659 H HD2  . TYR A 1 243 ? 12.89200 18.05600 12.58100  1.000 14.05000 ? 247 TYR A HD2  1 
ATOM   3660 H HE1  . TYR A 1 243 ? 15.51800 21.24700 14.62000  1.000 14.14000 ? 247 TYR A HE1  1 
ATOM   3661 H HE2  . TYR A 1 243 ? 12.51400 18.62100 14.78100  1.000 13.99000 ? 247 TYR A HE2  1 
ATOM   3662 H HH   . TYR A 1 243 ? 13.21200 19.80100 16.57300  1.000 14.84000 ? 247 TYR A HH   1 
ATOM   3663 N N    . ALA A 1 244 ? 17.40100 19.88900 9.55500   1.000 11.50664 ? 248 ALA A N    1 
ATOM   3664 C CA   . ALA A 1 244 ? 18.68300 20.55400 9.53800   1.000 12.49097 ? 248 ALA A CA   1 
ATOM   3665 C C    . ALA A 1 244 ? 18.63400 21.86200 8.78000   1.000 12.29621 ? 248 ALA A C    1 
ATOM   3666 O O    . ALA A 1 244 ? 17.79300 22.06500 7.89400   1.000 13.11473 ? 248 ALA A O    1 
ATOM   3667 C CB   . ALA A 1 244 ? 19.76900 19.66800 8.91300   1.000 12.36727 ? 248 ALA A CB   1 
ATOM   3668 H H    . ALA A 1 244 ? 16.87700 20.09000 8.90400   1.000 13.81000 ? 248 ALA A H    1 
ATOM   3669 H HA   . ALA A 1 244 ? 18.89600 20.76100 10.46100  1.000 15.00000 ? 248 ALA A HA   1 
ATOM   3670 H HB1  . ALA A 1 244 ? 20.61500 20.14100 8.93600   1.000 14.85000 ? 248 ALA A HB1  1 
ATOM   3671 H HB2  . ALA A 1 244 ? 19.83600 18.84500 9.42300   1.000 14.85000 ? 248 ALA A HB2  1 
ATOM   3672 H HB3  . ALA A 1 244 ? 19.52500 19.46900 7.99600   1.000 14.85000 ? 248 ALA A HB3  1 
ATOM   3673 N N    A VAL A 1 245 ? 19.52600 22.76000 9.17200   0.760 12.18830 ? 249 VAL A N    1 
ATOM   3674 N N    B VAL A 1 245 ? 19.58300 22.73200 9.11800   0.240 12.21462 ? 249 VAL A N    1 
ATOM   3675 C CA   A VAL A 1 245 ? 19.94800 23.87500 8.34100   0.760 12.56730 ? 249 VAL A CA   1 
ATOM   3676 C CA   B VAL A 1 245 ? 19.91600 23.91900 8.33900   0.240 12.34095 ? 249 VAL A CA   1 
ATOM   3677 C C    A VAL A 1 245 ? 21.34600 23.54900 7.84300   0.760 12.49097 ? 249 VAL A C    1 
ATOM   3678 C C    B VAL A 1 245 ? 21.36600 23.77400 7.87400   0.240 12.87523 ? 249 VAL A C    1 
ATOM   3679 O O    A VAL A 1 245 ? 22.19500 23.05600 8.60100   0.760 11.85142 ? 249 VAL A O    1 
ATOM   3680 O O    B VAL A 1 245 ? 22.28300 23.67500 8.69900   0.240 12.85944 ? 249 VAL A O    1 
ATOM   3681 C CB   A VAL A 1 245 ? 19.89200 25.24100 9.06200   0.760 13.99641 ? 249 VAL A CB   1 
ATOM   3682 C CB   B VAL A 1 245 ? 19.68800 25.21400 9.14000   0.240 12.33306 ? 249 VAL A CB   1 
ATOM   3683 C CG1  A VAL A 1 245 ? 20.18900 26.38600 8.09300   0.760 15.05444 ? 249 VAL A CG1  1 
ATOM   3684 C CG1  B VAL A 1 245 ? 20.27400 25.09500 10.54400  0.240 12.50939 ? 249 VAL A CG1  1 
ATOM   3685 C CG2  A VAL A 1 245 ? 18.53100 25.45300 9.69000   0.760 14.03063 ? 249 VAL A CG2  1 
ATOM   3686 C CG2  B VAL A 1 245 ? 20.27300 26.41700 8.40200   0.240 12.46465 ? 249 VAL A CG2  1 
ATOM   3687 H H    A VAL A 1 245 ? 19.91200 22.74400 9.94000   0.760 14.63000 ? 249 VAL A H    1 
ATOM   3688 H H    B VAL A 1 245 ? 20.06700 22.65100 9.82500   0.240 14.67000 ? 249 VAL A H    1 
ATOM   3689 H HA   A VAL A 1 245 ? 19.34500 23.95900 7.58600   0.760 15.09000 ? 249 VAL A HA   1 
ATOM   3690 H HA   B VAL A 1 245 ? 19.35500 23.96500 7.54900   0.240 14.82000 ? 249 VAL A HA   1 
ATOM   3691 H HB   A VAL A 1 245 ? 20.56800 25.24200 9.75700   0.760 16.80000 ? 249 VAL A HB   1 
ATOM   3692 H HB   B VAL A 1 245 ? 18.73300 25.35800 9.23100   0.240 14.81000 ? 249 VAL A HB   1 
ATOM   3693 H HG11 A VAL A 1 245 ? 20.07500 27.23000 8.55800   0.760 18.08000 ? 249 VAL A HG11 1 
ATOM   3694 H HG11 B VAL A 1 245 ? 20.21300 25.95600 10.98600  0.240 15.02000 ? 249 VAL A HG11 1 
ATOM   3695 H HG12 A VAL A 1 245 ? 21.10200 26.30400 7.77700   0.760 18.08000 ? 249 VAL A HG12 1 
ATOM   3696 H HG12 B VAL A 1 245 ? 19.77000 24.43200 11.04100  0.240 15.02000 ? 249 VAL A HG12 1 
ATOM   3697 H HG13 A VAL A 1 245 ? 19.57400 26.33500 7.34500   0.760 18.08000 ? 249 VAL A HG13 1 
ATOM   3698 H HG13 B VAL A 1 245 ? 21.20300 24.82200 10.47700  0.240 15.02000 ? 249 VAL A HG13 1 
ATOM   3699 H HG21 A VAL A 1 245 ? 18.49600 26.34300 10.07300  0.760 16.84000 ? 249 VAL A HG21 1 
ATOM   3700 H HG21 B VAL A 1 245 ? 20.11500 27.21700 8.92700   0.240 14.96000 ? 249 VAL A HG21 1 
ATOM   3701 H HG22 A VAL A 1 245 ? 17.85000 25.36000 9.00600   0.760 16.84000 ? 249 VAL A HG22 1 
ATOM   3702 H HG22 B VAL A 1 245 ? 21.22700 26.28200 8.28400   0.240 14.96000 ? 249 VAL A HG22 1 
ATOM   3703 H HG23 A VAL A 1 245 ? 18.39700 24.78900 10.38400  0.760 16.84000 ? 249 VAL A HG23 1 
ATOM   3704 H HG23 B VAL A 1 245 ? 19.84100 26.49800 7.53700   0.240 14.96000 ? 249 VAL A HG23 1 
ATOM   3705 N N    . VAL A 1 246 ? 21.56500 23.77500 6.55400   1.000 13.65953 ? 250 VAL A N    1 
ATOM   3706 C CA   . VAL A 1 246 ? 22.83100 23.47500 5.90400   1.000 14.25434 ? 250 VAL A CA   1 
ATOM   3707 C C    . VAL A 1 246 ? 23.29300 24.75200 5.22800   1.000 14.92547 ? 250 VAL A C    1 
ATOM   3708 O O    . VAL A 1 246 ? 22.51200 25.39000 4.51700   1.000 14.87284 ? 250 VAL A O    1 
ATOM   3709 C CB   . VAL A 1 246 ? 22.65400 22.34900 4.86500   1.000 14.41489 ? 250 VAL A CB   1 
ATOM   3710 C CG1  . VAL A 1 246 ? 23.93300 22.13700 4.07900   1.000 15.46764 ? 250 VAL A CG1  1 
ATOM   3711 C CG2  . VAL A 1 246 ? 22.17400 21.06600 5.51700   1.000 15.28604 ? 250 VAL A CG2  1 
ATOM   3712 H H    A VAL A 1 246 ? 20.97900 24.11100 6.02200   0.760 16.40000 ? 250 VAL A H    1 
ATOM   3713 H H    B VAL A 1 246 ? 20.94400 23.95700 5.98800   0.240 16.40000 ? 250 VAL A H    1 
ATOM   3714 H HA   . VAL A 1 246 ? 23.49400 23.19800 6.55600   1.000 17.11000 ? 250 VAL A HA   1 
ATOM   3715 H HB   . VAL A 1 246 ? 21.96700 22.61700 4.23500   1.000 17.31000 ? 250 VAL A HB   1 
ATOM   3716 H HG11 . VAL A 1 246 ? 23.85500 21.31900 3.56400   1.000 18.57000 ? 250 VAL A HG11 1 
ATOM   3717 H HG12 . VAL A 1 246 ? 24.06700 22.89100 3.48400   1.000 18.57000 ? 250 VAL A HG12 1 
ATOM   3718 H HG13 . VAL A 1 246 ? 24.67700 22.06800 4.69900   1.000 18.57000 ? 250 VAL A HG13 1 
ATOM   3719 H HG21 . VAL A 1 246 ? 22.07300 20.38400 4.83400   1.000 18.35000 ? 250 VAL A HG21 1 
ATOM   3720 H HG22 . VAL A 1 246 ? 22.82800 20.78200 6.17500   1.000 18.35000 ? 250 VAL A HG22 1 
ATOM   3721 H HG23 . VAL A 1 246 ? 21.32100 21.23100 5.94800   1.000 18.35000 ? 250 VAL A HG23 1 
ATOM   3722 N N    . TRP A 1 247 ? 24.56600 25.09600 5.40400   1.000 15.74136 ? 251 TRP A N    1 
ATOM   3723 C CA   . TRP A 1 247 ? 25.15800 26.27700 4.78900   1.000 15.82032 ? 251 TRP A CA   1 
ATOM   3724 C C    . TRP A 1 247 ? 26.17500 25.83400 3.74900   1.000 16.71516 ? 251 TRP A C    1 
ATOM   3725 O O    . TRP A 1 247 ? 27.36400 25.71100 4.06100   1.000 16.98362 ? 251 TRP A O    1 
ATOM   3726 C CB   . TRP A 1 247 ? 25.82700 27.14600 5.85600   1.000 16.84676 ? 251 TRP A CB   1 
ATOM   3727 C CG   . TRP A 1 247 ? 24.89800 27.90700 6.75700   1.000 17.07573 ? 251 TRP A CG   1 
ATOM   3728 C CD1  . TRP A 1 247 ? 24.47000 29.18500 6.58200   1.000 17.77582 ? 251 TRP A CD1  1 
ATOM   3729 C CD2  . TRP A 1 247 ? 24.28000 27.44200 7.97500   1.000 16.78886 ? 251 TRP A CD2  1 
ATOM   3730 N NE1  . TRP A 1 247 ? 23.62700 29.54800 7.60700   1.000 18.16007 ? 251 TRP A NE1  1 
ATOM   3731 C CE2  . TRP A 1 247 ? 23.50900 28.50500 8.48400   1.000 17.53105 ? 251 TRP A CE2  1 
ATOM   3732 C CE3  . TRP A 1 247 ? 24.33400 26.24800 8.69900   1.000 17.45999 ? 251 TRP A CE3  1 
ATOM   3733 C CZ2  . TRP A 1 247 ? 22.76800 28.40500 9.67400   1.000 18.13902 ? 251 TRP A CZ2  1 
ATOM   3734 C CZ3  . TRP A 1 247 ? 23.60200 26.15200 9.89100   1.000 17.74950 ? 251 TRP A CZ3  1 
ATOM   3735 C CH2  . TRP A 1 247 ? 22.82300 27.22600 10.35300  1.000 18.36799 ? 251 TRP A CH2  1 
ATOM   3736 H H    . TRP A 1 247 ? 25.11900 24.64900 5.88900   1.000 18.90000 ? 251 TRP A H    1 
ATOM   3737 H HA   . TRP A 1 247 ? 24.46800 26.79500 4.34500   1.000 18.99000 ? 251 TRP A HA   1 
ATOM   3738 H HB2  . TRP A 1 247 ? 26.36800 26.57200 6.42000   1.000 20.22000 ? 251 TRP A HB2  1 
ATOM   3739 H HB3  . TRP A 1 247 ? 26.39100 27.79700 5.40900   1.000 20.22000 ? 251 TRP A HB3  1 
ATOM   3740 H HD1  . TRP A 1 247 ? 24.71200 29.73500 5.87200   1.000 21.34000 ? 251 TRP A HD1  1 
ATOM   3741 H HE1  . TRP A 1 247 ? 23.23600 30.31000 7.68400   1.000 21.80000 ? 251 TRP A HE1  1 
ATOM   3742 H HE3  . TRP A 1 247 ? 24.84500 25.53200 8.39700   1.000 20.96000 ? 251 TRP A HE3  1 
ATOM   3743 H HZ2  . TRP A 1 247 ? 22.25800 29.11800 9.98700   1.000 21.77000 ? 251 TRP A HZ2  1 
ATOM   3744 H HZ3  . TRP A 1 247 ? 23.63200 25.36400 10.38400  1.000 21.31000 ? 251 TRP A HZ3  1 
ATOM   3745 H HH2  . TRP A 1 247 ? 22.33500 27.12900 11.13900  1.000 22.05000 ? 251 TRP A HH2  1 
ATOM   3746 N N    . PRO A 1 248 ? 25.77700 25.57300 2.50400   1.000 15.62029 ? 252 PRO A N    1 
ATOM   3747 C CA   . PRO A 1 248 ? 26.78100 25.33500 1.45600   1.000 15.63345 ? 252 PRO A CA   1 
ATOM   3748 C C    . PRO A 1 248 ? 27.59200 26.59800 1.25700   1.000 16.92835 ? 252 PRO A C    1 
ATOM   3749 O O    . PRO A 1 248 ? 27.07600 27.70900 1.36000   1.000 20.13136 ? 252 PRO A O    1 
ATOM   3750 C CB   . PRO A 1 248 ? 25.94400 25.01500 0.20500   1.000 16.32827 ? 252 PRO A CB   1 
ATOM   3751 C CG   . PRO A 1 248 ? 24.51700 24.91200 0.68400   1.000 16.15983 ? 252 PRO A CG   1 
ATOM   3752 C CD   . PRO A 1 248 ? 24.43300 25.73500 1.93300   1.000 15.87296 ? 252 PRO A CD   1 
ATOM   3753 H HA   . PRO A 1 248 ? 27.34800 24.57400 1.66000   1.000 18.77000 ? 252 PRO A HA   1 
ATOM   3754 H HB2  . PRO A 1 248 ? 26.03800 25.73100 -0.44400  1.000 19.61000 ? 252 PRO A HB2  1 
ATOM   3755 H HB3  . PRO A 1 248 ? 26.23900 24.17600 -0.18100  1.000 19.61000 ? 252 PRO A HB3  1 
ATOM   3756 H HG2  . PRO A 1 248 ? 23.92000 25.26000 0.00400   1.000 19.40000 ? 252 PRO A HG2  1 
ATOM   3757 H HG3  . PRO A 1 248 ? 24.30300 23.98400 0.87000   1.000 19.40000 ? 252 PRO A HG3  1 
ATOM   3758 H HD2  . PRO A 1 248 ? 24.25100 26.66600 1.72700   1.000 19.06000 ? 252 PRO A HD2  1 
ATOM   3759 H HD3  . PRO A 1 248 ? 23.75400 25.39000 2.53400   1.000 19.06000 ? 252 PRO A HD3  1 
ATOM   3760 N N    . THR A 1 249 ? 28.86700 26.44400 0.93900   1.000 14.46752 ? 254 THR A N    1 
ATOM   3761 C CA   . THR A 1 249 ? 29.64700 27.65100 0.74900   1.000 15.59134 ? 254 THR A CA   1 
ATOM   3762 C C    . THR A 1 249 ? 29.21900 28.35500 -0.53300  1.000 16.28353 ? 254 THR A C    1 
ATOM   3763 O O    . THR A 1 249 ? 28.86800 27.72400 -1.53900  1.000 17.00467 ? 254 THR A O    1 
ATOM   3764 C CB   . THR A 1 249 ? 31.15200 27.36100 0.73100   1.000 14.59912 ? 254 THR A CB   1 
ATOM   3765 O OG1  . THR A 1 249 ? 31.49700 26.63200 -0.43700  1.000 14.00957 ? 254 THR A OG1  1 
ATOM   3766 C CG2  . THR A 1 249 ? 31.58800 26.56900 1.96000   1.000 16.48619 ? 254 THR A CG2  1 
ATOM   3767 H H    . THR A 1 249 ? 29.27800 25.69700 0.83400   1.000 17.37000 ? 254 THR A H    1 
ATOM   3768 H HA   . THR A 1 249 ? 29.49300 28.24900 1.49700   1.000 18.72000 ? 254 THR A HA   1 
ATOM   3769 H HB   . THR A 1 249 ? 31.62300 28.20900 0.73700   1.000 17.53000 ? 254 THR A HB   1 
ATOM   3770 H HG1  . THR A 1 249 ? 31.10600 25.88900 -0.43800  1.000 16.82000 ? 254 THR A HG1  1 
ATOM   3771 H HG21 . THR A 1 249 ? 32.55100 26.45300 1.95600   1.000 19.79000 ? 254 THR A HG21 1 
ATOM   3772 H HG22 . THR A 1 249 ? 31.33100 27.04100 2.76800   1.000 19.79000 ? 254 THR A HG22 1 
ATOM   3773 H HG23 . THR A 1 249 ? 31.16600 25.69500 1.95900   1.000 19.79000 ? 254 THR A HG23 1 
ATOM   3774 N N    . GLY A 1 250 ? 29.25700 29.67700 -0.49500  1.000 17.53368 ? 255 GLY A N    1 
ATOM   3775 C CA   . GLY A 1 250 ? 29.02200 30.47200 -1.68500  1.000 18.72330 ? 255 GLY A CA   1 
ATOM   3776 C C    . GLY A 1 250 ? 27.57700 30.63000 -2.11400  1.000 19.64709 ? 255 GLY A C    1 
ATOM   3777 O O    . GLY A 1 250 ? 27.32800 31.24200 -3.16000  1.000 20.63405 ? 255 GLY A O    1 
ATOM   3778 H H    . GLY A 1 250 ? 29.41800 30.13900 0.21300   1.000 21.05000 ? 255 GLY A H    1 
ATOM   3779 H HA2  . GLY A 1 250 ? 29.37700 31.36200 -1.53200  1.000 22.48000 ? 255 GLY A HA2  1 
ATOM   3780 H HA3  . GLY A 1 250 ? 29.50000 30.06300 -2.42400  1.000 22.48000 ? 255 GLY A HA3  1 
ATOM   3781 N N    . ARG A 1 251 ? 26.61500 30.10700 -1.35700  1.000 18.27324 ? 256 ARG A N    1 
ATOM   3782 C CA   . ARG A 1 251 ? 25.20500 30.26400 -1.70000  1.000 18.07848 ? 256 ARG A CA   1 
ATOM   3783 C C    . ARG A 1 251 ? 24.39800 30.31700 -0.41000  1.000 17.60211 ? 256 ARG A C    1 
ATOM   3784 O O    . ARG A 1 251 ? 24.93300 30.14700 0.68700   1.000 18.20481 ? 256 ARG A O    1 
ATOM   3785 C CB   . ARG A 1 251 ? 24.71600 29.14300 -2.62500  1.000 19.43654 ? 256 ARG A CB   1 
ATOM   3786 C CG   . ARG A 1 251 ? 24.84700 27.74400 -2.05600  1.000 19.44970 ? 256 ARG A CG   1 
ATOM   3787 C CD   . ARG A 1 251 ? 24.49400 26.69700 -3.10500  1.000 20.77091 ? 256 ARG A CD   1 
ATOM   3788 N NE   . ARG A 1 251 ? 23.11500 26.84200 -3.55700  1.000 21.84999 ? 256 ARG A NE   1 
ATOM   3789 C CZ   . ARG A 1 251 ? 22.60900 26.30400 -4.66300  1.000 22.42637 ? 256 ARG A CZ   1 
ATOM   3790 N NH1  . ARG A 1 251 ? 23.35900 25.60200 -5.50100  1.000 23.67126 ? 256 ARG A NH1  1 
ATOM   3791 N NH2  . ARG A 1 251 ? 21.31700 26.48000 -4.93500  1.000 22.96591 ? 256 ARG A NH2  1 
ATOM   3792 H H    . ARG A 1 251 ? 26.75400 29.65600 -0.63900  1.000 21.93000 ? 256 ARG A H    1 
ATOM   3793 H HA   . ARG A 1 251 ? 25.08100 31.10400 -2.17000  1.000 21.70000 ? 256 ARG A HA   1 
ATOM   3794 H HB2  . ARG A 1 251 ? 23.77700 29.29200 -2.81800  1.000 23.33000 ? 256 ARG A HB2  1 
ATOM   3795 H HB3  . ARG A 1 251 ? 25.23200 29.17400 -3.44500  1.000 23.33000 ? 256 ARG A HB3  1 
ATOM   3796 H HG2  . ARG A 1 251 ? 25.76200 27.59600 -1.76900  1.000 23.35000 ? 256 ARG A HG2  1 
ATOM   3797 H HG3  . ARG A 1 251 ? 24.24300 27.64200 -1.30400  1.000 23.35000 ? 256 ARG A HG3  1 
ATOM   3798 H HD2  . ARG A 1 251 ? 25.08000 26.79900 -3.87200  1.000 24.93000 ? 256 ARG A HD2  1 
ATOM   3799 H HD3  . ARG A 1 251 ? 24.59900 25.81100 -2.72400  1.000 24.93000 ? 256 ARG A HD3  1 
ATOM   3800 H HE   . ARG A 1 251 ? 22.58700 27.31400 -3.06900  1.000 26.23000 ? 256 ARG A HE   1 
ATOM   3801 H HH11 . ARG A 1 251 ? 24.19500 25.48500 -5.33500  1.000 28.41000 ? 256 ARG A HH11 1 
ATOM   3802 H HH12 . ARG A 1 251 ? 23.01000 25.26300 -6.21000  1.000 28.41000 ? 256 ARG A HH12 1 
ATOM   3803 H HH21 . ARG A 1 251 ? 20.82200 26.93600 -4.39900  1.000 27.57000 ? 256 ARG A HH21 1 
ATOM   3804 H HH22 . ARG A 1 251 ? 20.97700 26.13700 -5.64700  1.000 27.57000 ? 256 ARG A HH22 1 
ATOM   3805 N N    . ALA A 1 252 ? 23.10100 30.58200 -0.55000  1.000 17.97847 ? 257 ALA A N    1 
ATOM   3806 C CA   . ALA A 1 252 ? 22.24200 30.73200 0.60000   1.000 17.34945 ? 257 ALA A CA   1 
ATOM   3807 C C    . ALA A 1 252 ? 22.01400 29.38700 1.27900   1.000 16.11509 ? 257 ALA A C    1 
ATOM   3808 O O    . ALA A 1 252 ? 22.10700 28.33000 0.65000   1.000 15.35710 ? 257 ALA A O    1 
ATOM   3809 C CB   . ALA A 1 252 ? 20.90100 31.30900 0.16600   1.000 18.19692 ? 257 ALA A CB   1 
ATOM   3810 H H    . ALA A 1 252 ? 22.70100 30.67800 -1.30500  1.000 21.58000 ? 257 ALA A H    1 
ATOM   3811 H HA   . ALA A 1 252 ? 22.65700 31.33100 1.24000   1.000 20.83000 ? 257 ALA A HA   1 
ATOM   3812 H HB1  . ALA A 1 252 ? 20.32600 31.39000 0.94300   1.000 21.84000 ? 257 ALA A HB1  1 
ATOM   3813 H HB2  . ALA A 1 252 ? 21.04700 32.18200 -0.23100  1.000 21.84000 ? 257 ALA A HB2  1 
ATOM   3814 H HB3  . ALA A 1 252 ? 20.49700 30.71300 -0.48400  1.000 21.84000 ? 257 ALA A HB3  1 
ATOM   3815 N N    . PRO A 1 253 ? 21.67100 29.40200 2.56000   1.000 15.84400 ? 258 PRO A N    1 
ATOM   3816 C CA   . PRO A 1 253 ? 21.45800 28.13700 3.26200   1.000 15.51765 ? 258 PRO A CA   1 
ATOM   3817 C C    . PRO A 1 253 ? 20.22100 27.39100 2.77000   1.000 14.53595 ? 258 PRO A C    1 
ATOM   3818 O O    . PRO A 1 253 ? 19.29100 27.95100 2.16800   1.000 15.24656 ? 258 PRO A O    1 
ATOM   3819 C CB   . PRO A 1 253 ? 21.30700 28.54500 4.73400   1.000 17.44156 ? 258 PRO A CB   1 
ATOM   3820 C CG   . PRO A 1 253 ? 21.09400 29.99500 4.72800   1.000 18.37852 ? 258 PRO A CG   1 
ATOM   3821 C CD   . PRO A 1 253 ? 21.66400 30.56200 3.46500   1.000 17.32839 ? 258 PRO A CD   1 
ATOM   3822 H HA   . PRO A 1 253 ? 22.23800 27.57100 3.15600   1.000 18.63000 ? 258 PRO A HA   1 
ATOM   3823 H HB2  . PRO A 1 253 ? 20.54500 28.08700 5.12300   1.000 20.94000 ? 258 PRO A HB2  1 
ATOM   3824 H HB3  . PRO A 1 253 ? 22.11400 28.31700 5.22000   1.000 20.94000 ? 258 PRO A HB3  1 
ATOM   3825 H HG2  . PRO A 1 253 ? 20.14100 30.17400 4.77200   1.000 22.07000 ? 258 PRO A HG2  1 
ATOM   3826 H HG3  . PRO A 1 253 ? 21.54000 30.38200 5.49700   1.000 22.07000 ? 258 PRO A HG3  1 
ATOM   3827 H HD2  . PRO A 1 253 ? 21.10000 31.27100 3.11700   1.000 20.80000 ? 258 PRO A HD2  1 
ATOM   3828 H HD3  . PRO A 1 253 ? 22.56400 30.89500 3.61000   1.000 20.80000 ? 258 PRO A HD3  1 
ATOM   3829 N N    . ILE A 1 254 ? 20.25200 26.08900 3.03300   1.000 13.27001 ? 259 ILE A N    1 
ATOM   3830 C CA   . ILE A 1 254 ? 19.17500 25.15700 2.73900   1.000 13.84640 ? 259 ILE A CA   1 
ATOM   3831 C C    . ILE A 1 254 ? 18.58600 24.70300 4.07100   1.000 13.95430 ? 259 ILE A C    1 
ATOM   3832 O O    . ILE A 1 254 ? 19.32800 24.40800 5.02100   1.000 14.00168 ? 259 ILE A O    1 
ATOM   3833 C CB   . ILE A 1 254 ? 19.72100 23.93300 1.97400   1.000 14.97285 ? 259 ILE A CB   1 
ATOM   3834 C CG1  . ILE A 1 254 ? 20.54800 24.34900 0.75700   1.000 16.53883 ? 259 ILE A CG1  1 
ATOM   3835 C CG2  . ILE A 1 254 ? 18.59800 22.97600 1.59600   1.000 14.84389 ? 259 ILE A CG2  1 
ATOM   3836 C CD1  . ILE A 1 254 ? 19.86100 25.24300 -0.15300  1.000 17.61001 ? 259 ILE A CD1  1 
ATOM   3837 H H    . ILE A 1 254 ? 20.92500 25.70300 3.40300   1.000 15.93000 ? 259 ILE A H    1 
ATOM   3838 H HA   . ILE A 1 254 ? 18.49000 25.59300 2.20900   1.000 16.62000 ? 259 ILE A HA   1 
ATOM   3839 H HB   . ILE A 1 254 ? 20.32100 23.46100 2.57200   1.000 17.98000 ? 259 ILE A HB   1 
ATOM   3840 H HG12 . ILE A 1 254 ? 21.34800 24.80100 1.06600   1.000 19.85000 ? 259 ILE A HG12 1 
ATOM   3841 H HG13 . ILE A 1 254 ? 20.78900 23.55200 0.25900   1.000 19.85000 ? 259 ILE A HG13 1 
ATOM   3842 H HG21 . ILE A 1 254 ? 18.96200 22.26200 1.04800   1.000 17.82000 ? 259 ILE A HG21 1 
ATOM   3843 H HG22 . ILE A 1 254 ? 18.21100 22.60700 2.40500   1.000 17.82000 ? 259 ILE A HG22 1 
ATOM   3844 H HG23 . ILE A 1 254 ? 17.92200 23.46200 1.09800   1.000 17.82000 ? 259 ILE A HG23 1 
ATOM   3845 H HD11 . ILE A 1 254 ? 20.36200 25.29600 -0.98200  1.000 21.14000 ? 259 ILE A HD11 1 
ATOM   3846 H HD12 . ILE A 1 254 ? 18.97200 24.89700 -0.32500  1.000 21.14000 ? 259 ILE A HD12 1 
ATOM   3847 H HD13 . ILE A 1 254 ? 19.80100 26.12200 0.25400   1.000 21.14000 ? 259 ILE A HD13 1 
ATOM   3848 N N    . VAL A 1 255 ? 17.26000 24.62600 4.15100   1.000 13.21211 ? 260 VAL A N    1 
ATOM   3849 C CA   . VAL A 1 255 ? 16.58300 24.09400 5.32900   1.000 13.71480 ? 260 VAL A CA   1 
ATOM   3850 C C    . VAL A 1 255 ? 15.83000 22.85900 4.86400   1.000 13.01998 ? 260 VAL A C    1 
ATOM   3851 O O    . VAL A 1 255 ? 15.15200 22.89700 3.82500   1.000 13.27001 ? 260 VAL A O    1 
ATOM   3852 C CB   . VAL A 1 255 ? 15.62900 25.12500 5.96200   1.000 13.82271 ? 260 VAL A CB   1 
ATOM   3853 C CG1  . VAL A 1 255 ? 15.05000 24.59700 7.26300   1.000 14.29645 ? 260 VAL A CG1  1 
ATOM   3854 C CG2  . VAL A 1 255 ? 16.32300 26.45800 6.18200   1.000 15.23604 ? 260 VAL A CG2  1 
ATOM   3855 H H    . VAL A 1 255 ? 16.72600 24.87900 3.52700   1.000 15.86000 ? 260 VAL A H    1 
ATOM   3856 H HA   . VAL A 1 255 ? 17.22800 23.84700 6.01000   1.000 16.47000 ? 260 VAL A HA   1 
ATOM   3857 H HB   . VAL A 1 255 ? 14.89500 25.27500 5.34600   1.000 16.59000 ? 260 VAL A HB   1 
ATOM   3858 H HG11 . VAL A 1 255 ? 14.40600 25.23700 7.60500   1.000 17.16000 ? 260 VAL A HG11 1 
ATOM   3859 H HG12 . VAL A 1 255 ? 14.61200 23.74800 7.09300   1.000 17.16000 ? 260 VAL A HG12 1 
ATOM   3860 H HG13 . VAL A 1 255 ? 15.76800 24.47600 7.90300   1.000 17.16000 ? 260 VAL A HG13 1 
ATOM   3861 H HG21 . VAL A 1 255 ? 15.70500 27.06900 6.61400   1.000 18.29000 ? 260 VAL A HG21 1 
ATOM   3862 H HG22 . VAL A 1 255 ? 17.10100 26.32100 6.74600   1.000 18.29000 ? 260 VAL A HG22 1 
ATOM   3863 H HG23 . VAL A 1 255 ? 16.59700 26.81700 5.32400   1.000 18.29000 ? 260 VAL A HG23 1 
ATOM   3864 N N    . LEU A 1 256 ? 15.95400 21.75300 5.60100   1.000 13.28844 ? 261 LEU A N    1 
ATOM   3865 C CA   . LEU A 1 256 ? 15.24700 20.55800 5.17900   1.000 13.43056 ? 261 LEU A CA   1 
ATOM   3866 C C    . LEU A 1 256 ? 14.86600 19.66800 6.34900   1.000 12.84101 ? 261 LEU A C    1 
ATOM   3867 O O    . LEU A 1 256 ? 15.46600 19.72300 7.43100   1.000 12.91471 ? 261 LEU A O    1 
ATOM   3868 C CB   . LEU A 1 256 ? 16.01000 19.75500 4.12200   1.000 13.61216 ? 261 LEU A CB   1 
ATOM   3869 C CG   . LEU A 1 256 ? 17.21800 18.94900 4.60200   1.000 14.40962 ? 261 LEU A CG   1 
ATOM   3870 C CD1  . LEU A 1 256 ? 17.64800 17.93000 3.54800   1.000 15.89138 ? 261 LEU A CD1  1 
ATOM   3871 C CD2  . LEU A 1 256 ? 18.41000 19.84300 4.95000   1.000 14.70966 ? 261 LEU A CD2  1 
ATOM   3872 H H    . LEU A 1 256 ? 16.42200 21.68000 6.31800   1.000 15.95000 ? 261 LEU A H    1 
ATOM   3873 H HA   . LEU A 1 256 ? 14.41400 20.86600 4.78900   1.000 16.12000 ? 261 LEU A HA   1 
ATOM   3874 H HB2  . LEU A 1 256 ? 15.39000 19.12500 3.72200   1.000 16.34000 ? 261 LEU A HB2  1 
ATOM   3875 H HB3  . LEU A 1 256 ? 16.33200 20.37600 3.45100   1.000 16.34000 ? 261 LEU A HB3  1 
ATOM   3876 H HG   . LEU A 1 256 ? 16.94700 18.48300 5.40900   1.000 17.30000 ? 261 LEU A HG   1 
ATOM   3877 H HD11 . LEU A 1 256 ? 18.40300 17.42400 3.88700   1.000 19.08000 ? 261 LEU A HD11 1 
ATOM   3878 H HD12 . LEU A 1 256 ? 16.90500 17.33300 3.36500   1.000 19.08000 ? 261 LEU A HD12 1 
ATOM   3879 H HD13 . LEU A 1 256 ? 17.90100 18.40000 2.73800   1.000 19.08000 ? 261 LEU A HD13 1 
ATOM   3880 H HD21 . LEU A 1 256 ? 19.17600 19.28400 5.15200   1.000 17.66000 ? 261 LEU A HD21 1 
ATOM   3881 H HD22 . LEU A 1 256 ? 18.60800 20.41400 4.19100   1.000 17.66000 ? 261 LEU A HD22 1 
ATOM   3882 H HD23 . LEU A 1 256 ? 18.18300 20.38500 5.72200   1.000 17.66000 ? 261 LEU A HD23 1 
ATOM   3883 N N    . ALA A 1 257 ? 13.87700 18.82000 6.08700   1.000 11.78562 ? 262 ALA A N    1 
ATOM   3884 C CA   . ALA A 1 257 ? 13.34200 17.88100 7.06100   1.000 12.25410 ? 262 ALA A CA   1 
ATOM   3885 C C    . ALA A 1 257 ? 13.11300 16.55600 6.35200   1.000 11.84879 ? 262 ALA A C    1 
ATOM   3886 O O    . ALA A 1 257 ? 12.54900 16.52000 5.24500   1.000 12.56730 ? 262 ALA A O    1 
ATOM   3887 C CB   . ALA A 1 257 ? 12.02700 18.39400 7.68100   1.000 12.93839 ? 262 ALA A CB   1 
ATOM   3888 H H    . ALA A 1 257 ? 13.48500 18.77000 5.32400   1.000 14.15000 ? 262 ALA A H    1 
ATOM   3889 H HA   . ALA A 1 257 ? 13.97000 17.74700 7.78700   1.000 14.71000 ? 262 ALA A HA   1 
ATOM   3890 H HB1  . ALA A 1 257 ? 11.69900 17.73700 8.31400   1.000 15.54000 ? 262 ALA A HB1  1 
ATOM   3891 H HB2  . ALA A 1 257 ? 12.19900 19.23400 8.13400   1.000 15.54000 ? 262 ALA A HB2  1 
ATOM   3892 H HB3  . ALA A 1 257 ? 11.37600 18.52700 6.97400   1.000 15.54000 ? 262 ALA A HB3  1 
ATOM   3893 N N    . VAL A 1 258 ? 13.51000 15.46800 7.00900   1.000 10.91183 ? 263 VAL A N    1 
ATOM   3894 C CA   . VAL A 1 258 ? 13.33800 14.11400 6.51000   1.000 11.75930 ? 263 VAL A CA   1 
ATOM   3895 C C    . VAL A 1 258 ? 12.74200 13.27000 7.63100   1.000 11.49612 ? 263 VAL A C    1 
ATOM   3896 O O    . VAL A 1 258 ? 13.37100 13.09500 8.69300   1.000 11.99618 ? 263 VAL A O    1 
ATOM   3897 C CB   . VAL A 1 258 ? 14.66000 13.49300 6.02100   1.000 12.98577 ? 263 VAL A CB   1 
ATOM   3898 C CG1  . VAL A 1 258 ? 14.41500 12.09400 5.54700   1.000 14.03326 ? 263 VAL A CG1  1 
ATOM   3899 C CG2  . VAL A 1 258 ? 15.31500 14.35900 4.94900   1.000 13.75691 ? 263 VAL A CG2  1 
ATOM   3900 H H    . VAL A 1 258 ? 13.89600 15.49400 7.77700   1.000 13.10000 ? 263 VAL A H    1 
ATOM   3901 H HA   . VAL A 1 258 ? 12.71500 14.13100 5.76600   1.000 14.12000 ? 263 VAL A HA   1 
ATOM   3902 H HB   . VAL A 1 258 ? 15.29000 13.45200 6.75800   1.000 15.59000 ? 263 VAL A HB   1 
ATOM   3903 H HG11 . VAL A 1 258 ? 15.19600 11.78300 5.06300   1.000 16.85000 ? 263 VAL A HG11 1 
ATOM   3904 H HG12 . VAL A 1 258 ? 14.25200 11.52400 6.31400   1.000 16.85000 ? 263 VAL A HG12 1 
ATOM   3905 H HG13 . VAL A 1 258 ? 13.64100 12.09000 4.96200   1.000 16.85000 ? 263 VAL A HG13 1 
ATOM   3906 H HG21 . VAL A 1 258 ? 16.14200 13.93900 4.66600   1.000 16.52000 ? 263 VAL A HG21 1 
ATOM   3907 H HG22 . VAL A 1 258 ? 14.71000 14.43900 4.19500   1.000 16.52000 ? 263 VAL A HG22 1 
ATOM   3908 H HG23 . VAL A 1 258 ? 15.49900 15.23600 5.32000   1.000 16.52000 ? 263 VAL A HG23 1 
ATOM   3909 N N    . TYR A 1 259 ? 11.54000 12.75600 7.40300   1.000 11.44085 ? 264 TYR A N    1 
ATOM   3910 C CA   . TYR A 1 259 ? 10.79300 11.96400 8.36900   1.000 10.78287 ? 264 TYR A CA   1 
ATOM   3911 C C    . TYR A 1 259 ? 10.44200 10.61000 7.76200   1.000 11.75141 ? 264 TYR A C    1 
ATOM   3912 O O    . TYR A 1 259 ? 10.12100 10.52600 6.57500   1.000 12.13040 ? 264 TYR A O    1 
ATOM   3913 C CB   . TYR A 1 259 ? 9.50000  12.71700 8.84200   1.000 10.81445 ? 264 TYR A CB   1 
ATOM   3914 C CG   . TYR A 1 259 ? 9.81600  13.78000 9.86000   1.000 10.56179 ? 264 TYR A CG   1 
ATOM   3915 C CD1  . TYR A 1 259 ? 10.48500 14.94600 9.54600   1.000 10.40914 ? 264 TYR A CD1  1 
ATOM   3916 C CD2  . TYR A 1 259 ? 9.43000  13.60400 11.19200  1.000 11.37768 ? 264 TYR A CD2  1 
ATOM   3917 C CE1  . TYR A 1 259 ? 10.84200 15.88500 10.50300  1.000 12.25410 ? 264 TYR A CE1  1 
ATOM   3918 C CE2  . TYR A 1 259 ? 9.77700  14.55300 12.14900  1.000 10.09068 ? 264 TYR A CE2  1 
ATOM   3919 C CZ   . TYR A 1 259 ? 10.45900 15.70100 11.81600  1.000 12.33043 ? 264 TYR A CZ   1 
ATOM   3920 O OH   . TYR A 1 259 ? 10.86200 16.66200 12.72600  1.000 10.24597 ? 264 TYR A OH   1 
ATOM   3921 H H    . TYR A 1 259 ? 11.11700 12.85900 6.66100   1.000 13.74000 ? 264 TYR A H    1 
ATOM   3922 H HA   . TYR A 1 259 ? 11.33900 11.80000 9.15300   1.000 12.95000 ? 264 TYR A HA   1 
ATOM   3923 H HB2  . TYR A 1 259 ? 9.07900  13.14100 8.07800   1.000 12.99000 ? 264 TYR A HB2  1 
ATOM   3924 H HB3  . TYR A 1 259 ? 8.88900  12.08100 9.24600   1.000 12.99000 ? 264 TYR A HB3  1 
ATOM   3925 H HD1  . TYR A 1 259 ? 10.70500 15.10800 8.65700   1.000 12.50000 ? 264 TYR A HD1  1 
ATOM   3926 H HD2  . TYR A 1 259 ? 8.94200  12.85200 11.43900  1.000 13.66000 ? 264 TYR A HD2  1 
ATOM   3927 H HE1  . TYR A 1 259 ? 11.33700 16.63500 10.26000  1.000 14.71000 ? 264 TYR A HE1  1 
ATOM   3928 H HE2  . TYR A 1 259 ? 9.54200  14.40800 13.03700  1.000 12.12000 ? 264 TYR A HE2  1 
ATOM   3929 H HH   . TYR A 1 259 ? 10.59700 16.45700 13.49600  1.000 12.30000 ? 264 TYR A HH   1 
ATOM   3930 N N    . THR A 1 260 ? 10.46300 9.55300  8.56500   1.000 10.96710 ? 265 THR A N    1 
ATOM   3931 C CA   . THR A 1 260 ? 10.03900 8.23900  8.11000   1.000 11.33557 ? 265 THR A CA   1 
ATOM   3932 C C    . THR A 1 260 ? 9.05500  7.60200  9.08600   1.000 12.85154 ? 265 THR A C    1 
ATOM   3933 O O    . THR A 1 260 ? 9.03200  7.91300  10.28200  1.000 12.63573 ? 265 THR A O    1 
ATOM   3934 C CB   . THR A 1 260 ? 11.18900 7.25100  7.88300   1.000 12.26726 ? 265 THR A CB   1 
ATOM   3935 O OG1  . THR A 1 260 ? 11.72800 6.76800  9.11500   1.000 12.00407 ? 265 THR A OG1  1 
ATOM   3936 C CG2  . THR A 1 260 ? 12.31100 7.90800  7.11300   1.000 12.54361 ? 265 THR A CG2  1 
ATOM   3937 H H    . THR A 1 260 ? 10.72000 9.57500  9.38600   1.000 13.17000 ? 265 THR A H    1 
ATOM   3938 H HA   . THR A 1 260 ? 9.59500  8.39000  7.26200   1.000 13.61000 ? 265 THR A HA   1 
ATOM   3939 H HB   . THR A 1 260 ? 10.83200 6.50300  7.38000   1.000 14.73000 ? 265 THR A HB   1 
ATOM   3940 H HG1  . THR A 1 260 ? 11.21200 6.19600  9.45000   1.000 14.41000 ? 265 THR A HG1  1 
ATOM   3941 H HG21 . THR A 1 260 ? 12.99900 7.25600  6.90900   1.000 15.06000 ? 265 THR A HG21 1 
ATOM   3942 H HG22 . THR A 1 260 ? 11.97200 8.27700  6.28300   1.000 15.06000 ? 265 THR A HG22 1 
ATOM   3943 H HG23 . THR A 1 260 ? 12.70000 8.62300  7.64000   1.000 15.06000 ? 265 THR A HG23 1 
ATOM   3944 N N    . ARG A 1 261 ? 8.27200  6.66600  8.56000   1.000 12.53835 ? 266 ARG A N    1 
ATOM   3945 C CA   . ARG A 1 261 ? 7.47300  5.73900  9.34800   1.000 12.87786 ? 266 ARG A CA   1 
ATOM   3946 C C    . ARG A 1 261 ? 7.24800  4.49000  8.50200   1.000 12.71731 ? 266 ARG A C    1 
ATOM   3947 O O    . ARG A 1 261 ? 7.56900  4.46200  7.31900   1.000 13.34897 ? 266 ARG A O    1 
ATOM   3948 C CB   . ARG A 1 261 ? 6.14500  6.34800  9.80400   1.000 12.57519 ? 266 ARG A CB   1 
ATOM   3949 C CG   . ARG A 1 261 ? 5.23300  6.73800  8.69600   1.000 14.31224 ? 266 ARG A CG   1 
ATOM   3950 C CD   . ARG A 1 261 ? 3.90900  7.20400  9.27600   1.000 16.53619 ? 266 ARG A CD   1 
ATOM   3951 N NE   . ARG A 1 261 ? 3.48400  8.44200  8.64700   1.000 21.41836 ? 266 ARG A NE   1 
ATOM   3952 C CZ   . ARG A 1 261 ? 3.02200  8.52500  7.40600   1.000 21.59996 ? 266 ARG A CZ   1 
ATOM   3953 N NH1  . ARG A 1 261 ? 2.87800  7.44900  6.64900   1.000 24.40029 ? 266 ARG A NH1  1 
ATOM   3954 N NH2  . ARG A 1 261 ? 2.74600  9.72300  6.90300   1.000 17.57842 ? 266 ARG A NH2  1 
ATOM   3955 H H    . ARG A 1 261 ? 8.18300  6.54300  7.71400   1.000 15.05000 ? 266 ARG A H    1 
ATOM   3956 H HA   . ARG A 1 261 ? 7.96000  5.49800  10.15200  1.000 15.46000 ? 266 ARG A HA   1 
ATOM   3957 H HB2  . ARG A 1 261 ? 5.67800  5.69700  10.35200  1.000 15.10000 ? 266 ARG A HB2  1 
ATOM   3958 H HB3  . ARG A 1 261 ? 6.33300  7.14500  10.32300  1.000 15.10000 ? 266 ARG A HB3  1 
ATOM   3959 H HG2  . ARG A 1 261 ? 5.62500  7.46400  8.18600   1.000 17.18000 ? 266 ARG A HG2  1 
ATOM   3960 H HG3  . ARG A 1 261 ? 5.07100  5.97600  8.11800   1.000 17.18000 ? 266 ARG A HG3  1 
ATOM   3961 H HD2  . ARG A 1 261 ? 3.23100  6.52800  9.11900   1.000 19.85000 ? 266 ARG A HD2  1 
ATOM   3962 H HD3  . ARG A 1 261 ? 4.00900  7.35900  10.22800  1.000 19.85000 ? 266 ARG A HD3  1 
ATOM   3963 H HE   . ARG A 1 261 ? 3.53500  9.16600  9.10700   1.000 25.71000 ? 266 ARG A HE   1 
ATOM   3964 H HH11 . ARG A 1 261 ? 3.08700  6.67500  6.95900   1.000 29.29000 ? 266 ARG A HH11 1 
ATOM   3965 H HH12 . ARG A 1 261 ? 2.57700  7.52500  5.84700   1.000 29.29000 ? 266 ARG A HH12 1 
ATOM   3966 H HH21 . ARG A 1 261 ? 2.86800  10.42800 7.38000   1.000 21.10000 ? 266 ARG A HH21 1 
ATOM   3967 H HH22 . ARG A 1 261 ? 2.44600  9.79300  6.10000   1.000 21.10000 ? 266 ARG A HH22 1 
ATOM   3968 N N    . ALA A 1 262 ? 6.66400  3.46100  9.10000   1.000 12.73837 ? 267 ALA A N    1 
ATOM   3969 C CA   . ALA A 1 262 ? 6.44800  2.18500  8.43400   1.000 12.94366 ? 267 ALA A CA   1 
ATOM   3970 C C    . ALA A 1 262 ? 5.26300  1.50500  9.09100   1.000 12.40675 ? 267 ALA A C    1 
ATOM   3971 O O    . ALA A 1 262 ? 4.91000  1.83000  10.23300  1.000 12.66994 ? 267 ALA A O    1 
ATOM   3972 C CB   . ALA A 1 262 ? 7.69000  1.28400  8.52500   1.000 13.72796 ? 267 ALA A CB   1 
ATOM   3973 H H    . ALA A 1 262 ? 6.37700  3.47700  9.91000   1.000 15.29000 ? 267 ALA A H    1 
ATOM   3974 H HA   . ALA A 1 262 ? 6.24500  2.33500  7.49700   1.000 15.54000 ? 267 ALA A HA   1 
ATOM   3975 H HB1  . ALA A 1 262 ? 7.50400  0.44300  8.07900   1.000 16.48000 ? 267 ALA A HB1  1 
ATOM   3976 H HB2  . ALA A 1 262 ? 8.43600  1.72900  8.09200   1.000 16.48000 ? 267 ALA A HB2  1 
ATOM   3977 H HB3  . ALA A 1 262 ? 7.89700  1.12500  9.45900   1.000 16.48000 ? 267 ALA A HB3  1 
ATOM   3978 N N    . PRO A 1 263 ? 4.64700  0.53400  8.41200   1.000 13.25685 ? 268 PRO A N    1 
ATOM   3979 C CA   . PRO A 1 263 ? 3.34800  0.04400  8.88600   1.000 13.03577 ? 268 PRO A CA   1 
ATOM   3980 C C    . PRO A 1 263 ? 3.37700  -0.84900 10.11700  1.000 13.40687 ? 268 PRO A C    1 
ATOM   3981 O O    . PRO A 1 263 ? 2.36700  -0.88200 10.83800  1.000 13.35423 ? 268 PRO A O    1 
ATOM   3982 C CB   . PRO A 1 263 ? 2.76700  -0.70000 7.67600   1.000 14.87810 ? 268 PRO A CB   1 
ATOM   3983 C CG   . PRO A 1 263 ? 3.92800  -0.94300 6.80300   1.000 16.24668 ? 268 PRO A CG   1 
ATOM   3984 C CD   . PRO A 1 263 ? 4.93300  0.10400  7.03300   1.000 14.38594 ? 268 PRO A CD   1 
ATOM   3985 H HA   . PRO A 1 263 ? 2.80400  0.82000  9.09200   1.000 15.65000 ? 268 PRO A HA   1 
ATOM   3986 H HB2  . PRO A 1 263 ? 2.36300  -1.53500 7.96100   1.000 17.86000 ? 268 PRO A HB2  1 
ATOM   3987 H HB3  . PRO A 1 263 ? 2.10500  -0.14700 7.23100   1.000 17.86000 ? 268 PRO A HB3  1 
ATOM   3988 H HG2  . PRO A 1 263 ? 4.30200  -1.81300 7.01500   1.000 19.50000 ? 268 PRO A HG2  1 
ATOM   3989 H HG3  . PRO A 1 263 ? 3.63400  -0.92400 5.87900   1.000 19.50000 ? 268 PRO A HG3  1 
ATOM   3990 H HD2  . PRO A 1 263 ? 5.83200  -0.25500 6.96000   1.000 17.27000 ? 268 PRO A HD2  1 
ATOM   3991 H HD3  . PRO A 1 263 ? 4.81800  0.83800  6.41000   1.000 17.27000 ? 268 PRO A HD3  1 
ATOM   3992 N N    . ASN A 1 264 ? 4.45000  -1.58600 10.37300  1.000 13.97799 ? 269 ASN A N    1 
ATOM   3993 C CA   . ASN A 1 264 ? 4.45600  -2.60000 11.41600  1.000 14.35962 ? 269 ASN A CA   1 
ATOM   3994 C C    . ASN A 1 264 ? 5.24700  -2.13900 12.62800  1.000 13.75691 ? 269 ASN A C    1 
ATOM   3995 O O    . ASN A 1 264 ? 6.28000  -1.48600 12.49600  1.000 13.92272 ? 269 ASN A O    1 
ATOM   3996 C CB   . ASN A 1 264 ? 5.08500  -3.88400 10.89000  1.000 15.78347 ? 269 ASN A CB   1 
ATOM   3997 C CG   . ASN A 1 264 ? 4.32200  -4.45000 9.72700   1.000 18.93122 ? 269 ASN A CG   1 
ATOM   3998 O OD1  . ASN A 1 264 ? 3.10900  -4.56600 9.77500   1.000 18.91806 ? 269 ASN A OD1  1 
ATOM   3999 N ND2  . ASN A 1 264 ? 5.02300  -4.75300 8.65600   1.000 23.32385 ? 269 ASN A ND2  1 
ATOM   4000 H H    . ASN A 1 264 ? 5.19600  -1.51400 9.95000   1.000 16.78000 ? 269 ASN A H    1 
ATOM   4001 H HA   . ASN A 1 264 ? 3.54300  -2.76300 11.69800  1.000 17.24000 ? 269 ASN A HA   1 
ATOM   4002 H HB2  . ASN A 1 264 ? 5.99000  -3.69900 10.59700  1.000 18.95000 ? 269 ASN A HB2  1 
ATOM   4003 H HB3  . ASN A 1 264 ? 5.09400  -4.54800 11.59800  1.000 18.95000 ? 269 ASN A HB3  1 
ATOM   4004 H HD21 . ASN A 1 264 ? 4.63100  -5.08000 7.96400   1.000 28.00000 ? 269 ASN A HD21 1 
ATOM   4005 H HD22 . ASN A 1 264 ? 5.87300  -4.62300 8.64800   1.000 28.00000 ? 269 ASN A HD22 1 
ATOM   4006 N N    . LYS A 1 265 ? 4.74800  -2.49400 13.81700  1.000 12.82785 ? 270 LYS A N    1 
ATOM   4007 C CA   . LYS A 1 265 ? 5.38500  -1.99300 15.03700  1.000 12.89365 ? 270 LYS A CA   1 
ATOM   4008 C C    . LYS A 1 265 ? 6.86400  -2.34400 15.08500  1.000 15.36763 ? 270 LYS A C    1 
ATOM   4009 O O    . LYS A 1 265 ? 7.69100  -1.53700 15.53700  1.000 15.54923 ? 270 LYS A O    1 
ATOM   4010 C CB   . LYS A 1 265 ? 4.66400  -2.52100 16.28000  1.000 13.60426 ? 270 LYS A CB   1 
ATOM   4011 C CG   . LYS A 1 265 ? 5.14500  -1.86500 17.56500  1.000 14.66228 ? 270 LYS A CG   1 
ATOM   4012 C CD   . LYS A 1 265 ? 4.35300  -2.30900 18.79500  1.000 16.11772 ? 270 LYS A CD   1 
ATOM   4013 C CE   . LYS A 1 265 ? 4.97400  -1.70900 20.04600  1.000 18.94438 ? 270 LYS A CE   1 
ATOM   4014 N NZ   . LYS A 1 265 ? 4.23600  -2.10300 21.27400  1.000 21.02884 ? 270 LYS A NZ   1 
ATOM   4015 H H    . LYS A 1 265 ? 4.06700  -3.00500 13.94000  1.000 15.40000 ? 270 LYS A H    1 
ATOM   4016 H HA   . LYS A 1 265 ? 5.30800  -1.02600 15.04100  1.000 15.48000 ? 270 LYS A HA   1 
ATOM   4017 H HB2  . LYS A 1 265 ? 3.71400  -2.34600 16.19200  1.000 16.33000 ? 270 LYS A HB2  1 
ATOM   4018 H HB3  . LYS A 1 265 ? 4.82000  -3.47500 16.35400  1.000 16.33000 ? 270 LYS A HB3  1 
ATOM   4019 H HG2  . LYS A 1 265 ? 6.07600  -2.09800 17.70900  1.000 17.60000 ? 270 LYS A HG2  1 
ATOM   4020 H HG3  . LYS A 1 265 ? 5.05300  -0.90300 17.48200  1.000 17.60000 ? 270 LYS A HG3  1 
ATOM   4021 H HD2  . LYS A 1 265 ? 3.43600  -2.00200 18.72300  1.000 19.35000 ? 270 LYS A HD2  1 
ATOM   4022 H HD3  . LYS A 1 265 ? 4.37500  -3.27600 18.86800  1.000 19.35000 ? 270 LYS A HD3  1 
ATOM   4023 H HE2  . LYS A 1 265 ? 5.88900  -2.01900 20.12900  1.000 22.74000 ? 270 LYS A HE2  1 
ATOM   4024 H HE3  . LYS A 1 265 ? 4.95600  -0.74100 19.97900  1.000 22.74000 ? 270 LYS A HE3  1 
ATOM   4025 H HZ1  . LYS A 1 265 ? 4.62700  -1.74800 21.99000  1.000 25.24000 ? 270 LYS A HZ1  1 
ATOM   4026 H HZ2  . LYS A 1 265 ? 3.39600  -1.81400 21.23000  1.000 25.24000 ? 270 LYS A HZ2  1 
ATOM   4027 H HZ3  . LYS A 1 265 ? 4.23300  -2.98900 21.35600  1.000 25.24000 ? 270 LYS A HZ3  1 
ATOM   4028 N N    . ASP A 1 266 ? 7.22000  -3.54600 14.65700  1.000 15.72557 ? 271 ASP A N    1 
ATOM   4029 C CA   . ASP A 1 266 ? 8.61900  -3.94800 14.76400  1.000 18.17586 ? 271 ASP A CA   1 
ATOM   4030 C C    . ASP A 1 266 ? 9.42400  -3.67100 13.49900  1.000 17.29155 ? 271 ASP A C    1 
ATOM   4031 O O    . ASP A 1 266 ? 10.56900 -4.11700 13.40200  1.000 17.61527 ? 271 ASP A O    1 
ATOM   4032 C CB   . ASP A 1 266 ? 8.74600  -5.38800 15.26200  1.000 23.68968 ? 271 ASP A CB   1 
ATOM   4033 C CG   . ASP A 1 266 ? 8.31100  -6.39600 14.26900  1.000 27.84281 ? 271 ASP A CG   1 
ATOM   4034 O OD1  . ASP A 1 266 ? 7.71700  -6.00900 13.24500  1.000 29.74567 ? 271 ASP A OD1  1 
ATOM   4035 O OD2  . ASP A 1 266 ? 8.57800  -7.59700 14.52900  1.000 30.60367 ? 271 ASP A OD2  1 
ATOM   4036 H H    . ASP A 1 266 ? 6.68900  -4.12800 14.31300  1.000 18.88000 ? 271 ASP A H    1 
ATOM   4037 H HA   . ASP A 1 266 ? 9.04300  -3.41500 15.45500  1.000 21.82000 ? 271 ASP A HA   1 
ATOM   4038 H HB2  . ASP A 1 266 ? 9.67600  -5.56400 15.47600  1.000 28.44000 ? 271 ASP A HB2  1 
ATOM   4039 H HB3  . ASP A 1 266 ? 8.19700  -5.49500 16.05500  1.000 28.44000 ? 271 ASP A HB3  1 
ATOM   4040 N N    . ASP A 1 267 ? 8.87500  -2.90500 12.55300  1.000 15.99402 ? 272 ASP A N    1 
ATOM   4041 C CA   . ASP A 1 267 ? 9.70900  -2.42000 11.46100  1.000 15.49396 ? 272 ASP A CA   1 
ATOM   4042 C C    . ASP A 1 267 ? 10.80300 -1.51200 12.01500  1.000 16.75727 ? 272 ASP A C    1 
ATOM   4043 O O    . ASP A 1 267 ? 10.55400 -0.63400 12.83800  1.000 16.13088 ? 272 ASP A O    1 
ATOM   4044 C CB   . ASP A 1 267 ? 8.87500  -1.62200 10.45000  1.000 15.78874 ? 272 ASP A CB   1 
ATOM   4045 C CG   . ASP A 1 267 ? 8.02900  -2.50100 9.54900   1.000 16.35196 ? 272 ASP A CG   1 
ATOM   4046 O OD1  . ASP A 1 267 ? 8.32400  -3.71100 9.39700   1.000 18.87332 ? 272 ASP A OD1  1 
ATOM   4047 O OD2  . ASP A 1 267 ? 7.07000  -1.94900 8.95900   1.000 15.50975 ? 272 ASP A OD2  1 
ATOM   4048 H H    . ASP A 1 267 ? 8.05000  -2.66200 12.52400  1.000 19.20000 ? 272 ASP A H    1 
ATOM   4049 H HA   . ASP A 1 267 ? 10.10500 -3.17900 11.00400  1.000 18.60000 ? 272 ASP A HA   1 
ATOM   4050 H HB2  . ASP A 1 267 ? 8.27800  -1.02900 10.93300  1.000 18.95000 ? 272 ASP A HB2  1 
ATOM   4051 H HB3  . ASP A 1 267 ? 9.47200  -1.10500 9.88700   1.000 18.95000 ? 272 ASP A HB3  1 
ATOM   4052 N N    . LYS A 1 268 ? 12.01500 -1.68900 11.52900  1.000 17.98374 ? 273 LYS A N    1 
ATOM   4053 C CA   A LYS A 1 268 ? 13.11300 -0.88500 12.03500  0.460 17.63369 ? 273 LYS A CA   1 
ATOM   4054 C CA   B LYS A 1 268 ? 13.15900 -0.91800 11.99400  0.540 17.68896 ? 273 LYS A CA   1 
ATOM   4055 C C    . LYS A 1 268 ? 13.31900 0.35800  11.17600  1.000 16.25195 ? 273 LYS A C    1 
ATOM   4056 O O    . LYS A 1 268 ? 13.05800 0.37200  9.97200   1.000 17.37577 ? 273 LYS A O    1 
ATOM   4057 C CB   A LYS A 1 268 ? 14.41200 -1.69100 12.13700  0.460 19.39969 ? 273 LYS A CB   1 
ATOM   4058 C CB   B LYS A 1 268 ? 14.43600 -1.75300 11.87400  0.540 19.82869 ? 273 LYS A CB   1 
ATOM   4059 C CG   A LYS A 1 268 ? 14.47400 -2.66100 13.32800  0.460 21.42362 ? 273 LYS A CG   1 
ATOM   4060 C CG   B LYS A 1 268 ? 14.40600 -3.05100 12.67300  0.540 21.99737 ? 273 LYS A CG   1 
ATOM   4061 C CD   A LYS A 1 268 ? 14.19300 -1.98200 14.67600  0.460 23.28963 ? 273 LYS A CD   1 
ATOM   4062 C CD   B LYS A 1 268 ? 15.71600 -3.82600 12.56900  0.540 24.18974 ? 273 LYS A CD   1 
ATOM   4063 C CE   A LYS A 1 268 ? 15.16300 -0.84600 14.97400  0.460 24.25028 ? 273 LYS A CE   1 
ATOM   4064 C CE   B LYS A 1 268 ? 16.20400 -4.29500 13.94000  0.540 25.50306 ? 273 LYS A CE   1 
ATOM   4065 N NZ   A LYS A 1 268 ? 14.47700 0.33200  15.57800  0.460 25.04248 ? 273 LYS A NZ   1 
ATOM   4066 N NZ   B LYS A 1 268 ? 15.11700 -4.85700 14.78800  0.540 26.54529 ? 273 LYS A NZ   1 
ATOM   4067 H H    A LYS A 1 268 ? 12.22500 -2.25700 10.91800  0.460 21.59000 ? 273 LYS A H    1 
ATOM   4068 H H    B LYS A 1 268 ? 12.20900 -2.26100 10.91600  0.540 21.59000 ? 273 LYS A H    1 
ATOM   4069 H HA   A LYS A 1 268 ? 12.89100 -0.59200 12.93200  0.460 21.17000 ? 273 LYS A HA   1 
ATOM   4070 H HA   B LYS A 1 268 ? 13.02000 -0.67000 12.92200  0.540 21.23000 ? 273 LYS A HA   1 
ATOM   4071 H HB2  A LYS A 1 268 ? 14.51300 -2.21600 11.32700  0.460 23.28000 ? 273 LYS A HB2  1 
ATOM   4072 H HB2  B LYS A 1 268 ? 14.56900 -1.98400 10.94100  0.540 23.80000 ? 273 LYS A HB2  1 
ATOM   4073 H HB3  A LYS A 1 268 ? 15.15300 -1.07200 12.22600  0.460 23.28000 ? 273 LYS A HB3  1 
ATOM   4074 H HB3  B LYS A 1 268 ? 15.18400 -1.22600 12.19600  0.540 23.80000 ? 273 LYS A HB3  1 
ATOM   4075 H HG2  A LYS A 1 268 ? 13.81200 -3.35800 13.20100  0.460 25.71000 ? 273 LYS A HG2  1 
ATOM   4076 H HG2  B LYS A 1 268 ? 14.25100 -2.84500 13.60800  0.540 26.40000 ? 273 LYS A HG2  1 
ATOM   4077 H HG3  A LYS A 1 268 ? 15.36200 -3.05100 13.37000  0.460 25.71000 ? 273 LYS A HG3  1 
ATOM   4078 H HG3  B LYS A 1 268 ? 13.69400 -3.61600 12.33400  0.540 26.40000 ? 273 LYS A HG3  1 
ATOM   4079 H HD2  A LYS A 1 268 ? 13.29500 -1.61400 14.66500  0.460 27.95000 ? 273 LYS A HD2  1 
ATOM   4080 H HD2  B LYS A 1 268 ? 15.58300 -4.60700 12.01000  0.540 29.03000 ? 273 LYS A HD2  1 
ATOM   4081 H HD3  A LYS A 1 268 ? 14.27300 -2.63900 15.38500  0.460 27.95000 ? 273 LYS A HD3  1 
ATOM   4082 H HD3  B LYS A 1 268 ? 16.39700 -3.25400 12.18300  0.540 29.03000 ? 273 LYS A HD3  1 
ATOM   4083 H HE2  A LYS A 1 268 ? 15.83600 -1.15700 15.59900  0.460 29.11000 ? 273 LYS A HE2  1 
ATOM   4084 H HE2  B LYS A 1 268 ? 16.87400 -4.98600 13.81700  0.540 30.61000 ? 273 LYS A HE2  1 
ATOM   4085 H HE3  A LYS A 1 268 ? 15.58300 -0.56000 14.14800  0.460 29.11000 ? 273 LYS A HE3  1 
ATOM   4086 H HE3  B LYS A 1 268 ? 16.59000 -3.54000 14.41200  0.540 30.61000 ? 273 LYS A HE3  1 
ATOM   4087 H HZ1  A LYS A 1 268 ? 15.06700 0.97700  15.74200  0.460 30.06000 ? 273 LYS A HZ1  1 
ATOM   4088 H HZ1  B LYS A 1 268 ? 15.46600 -5.28300 15.48800  0.540 31.86000 ? 273 LYS A HZ1  1 
ATOM   4089 H HZ2  A LYS A 1 268 ? 13.85700 0.64200  15.02000  0.460 30.06000 ? 273 LYS A HZ2  1 
ATOM   4090 H HZ2  B LYS A 1 268 ? 14.59100 -4.20200 15.08200  0.540 31.86000 ? 273 LYS A HZ2  1 
ATOM   4091 H HZ3  A LYS A 1 268 ? 14.08600 0.09700  16.34200  0.460 30.06000 ? 273 LYS A HZ3  1 
ATOM   4092 H HZ3  B LYS A 1 268 ? 14.62800 -5.43000 14.31500  0.540 31.86000 ? 273 LYS A HZ3  1 
ATOM   4093 N N    . HIS A 1 269 ? 13.74300 1.43100  11.82800  1.000 14.57017 ? 274 HIS A N    1 
ATOM   4094 C CA   . HIS A 1 269 ? 14.09800 2.63600  11.09600  1.000 13.62005 ? 274 HIS A CA   1 
ATOM   4095 C C    . HIS A 1 269 ? 15.43600 2.41400  10.39600  1.000 14.55174 ? 274 HIS A C    1 
ATOM   4096 O O    . HIS A 1 269 ? 16.12700 1.41100  10.62400  1.000 15.18603 ? 274 HIS A O    1 
ATOM   4097 C CB   . HIS A 1 269 ? 14.15400 3.83600  12.04100  1.000 14.95179 ? 274 HIS A CB   1 
ATOM   4098 C CG   . HIS A 1 269 ? 15.30500 3.78500  12.98700  1.000 16.72569 ? 274 HIS A CG   1 
ATOM   4099 N ND1  . HIS A 1 269 ? 15.28400 3.03700  14.14200  1.000 19.06018 ? 274 HIS A ND1  1 
ATOM   4100 C CD2  . HIS A 1 269 ? 16.52300 4.36900  12.92800  1.000 17.57316 ? 274 HIS A CD2  1 
ATOM   4101 C CE1  . HIS A 1 269 ? 16.44800 3.16300  14.75300  1.000 20.08399 ? 274 HIS A CE1  1 
ATOM   4102 N NE2  . HIS A 1 269 ? 17.21100 3.97400  14.04300  1.000 18.94174 ? 274 HIS A NE2  1 
ATOM   4103 H H    . HIS A 1 269 ? 13.83200 1.48600  12.68100  1.000 17.49000 ? 274 HIS A H    1 
ATOM   4104 H HA   . HIS A 1 269 ? 13.42900 2.83700  10.42300  1.000 16.35000 ? 274 HIS A HA   1 
ATOM   4105 H HB2  . HIS A 1 269 ? 14.23600 4.64600  11.51500  1.000 17.95000 ? 274 HIS A HB2  1 
ATOM   4106 H HB3  . HIS A 1 269 ? 13.33800 3.86100  12.56500  1.000 17.95000 ? 274 HIS A HB3  1 
ATOM   4107 H HD2  . HIS A 1 269 ? 16.83400 4.93300  12.25700  1.000 21.09000 ? 274 HIS A HD2  1 
ATOM   4108 H HE1  . HIS A 1 269 ? 16.69000 2.74900  15.55000  1.000 24.11000 ? 274 HIS A HE1  1 
ATOM   4109 H HE2  . HIS A 1 269 ? 18.01100 4.21400  14.24800  1.000 22.74000 ? 274 HIS A HE2  1 
ATOM   4110 N N    . SER A 1 270 ? 15.79000 3.36800  9.53500   1.000 14.94653 ? 275 SER A N    1 
ATOM   4111 C CA   . SER A 1 270 ? 17.05000 3.30800  8.80700   1.000 14.58070 ? 275 SER A CA   1 
ATOM   4112 C C    . SER A 1 270 ? 17.68500 4.68500  8.72200   1.000 14.26224 ? 275 SER A C    1 
ATOM   4113 O O    . SER A 1 270 ? 17.10300 5.61100  8.15100   1.000 14.49121 ? 275 SER A O    1 
ATOM   4114 C CB   . SER A 1 270 ? 16.83000 2.74300  7.39800   1.000 15.74399 ? 275 SER A CB   1 
ATOM   4115 O OG   . SER A 1 270 ? 18.00600 2.92600  6.62200   1.000 16.62831 ? 275 SER A OG   1 
ATOM   4116 H H    . SER A 1 270 ? 15.31400 4.06100  9.35800   1.000 17.95000 ? 275 SER A H    1 
ATOM   4117 H HA   . SER A 1 270 ? 17.66300 2.74000  9.29900   1.000 17.50000 ? 275 SER A HA   1 
ATOM   4118 H HB2  . SER A 1 270 ? 16.63100 1.79600  7.46000   1.000 18.90000 ? 275 SER A HB2  1 
ATOM   4119 H HB3  . SER A 1 270 ? 16.09200 3.21100  6.97700   1.000 18.90000 ? 275 SER A HB3  1 
ATOM   4120 H HG   . SER A 1 270 ? 17.95200 2.48500  5.90900   1.000 19.96000 ? 275 SER A HG   1 
ATOM   4121 N N    . GLU A 1 271 ? 18.88400 4.81900  9.28600   1.000 13.89640 ? 276 GLU A N    1 
ATOM   4122 C CA   . GLU A 1 271 ? 19.60500 6.07500  9.13300   1.000 14.36751 ? 276 GLU A CA   1 
ATOM   4123 C C    . GLU A 1 271 ? 20.05200 6.26800  7.68900   1.000 14.43857 ? 276 GLU A C    1 
ATOM   4124 O O    . GLU A 1 271 ? 20.04400 7.39500  7.17500   1.000 13.67532 ? 276 GLU A O    1 
ATOM   4125 C CB   . GLU A 1 271 ? 20.80600 6.10900  10.07700  1.000 14.82809 ? 276 GLU A CB   1 
ATOM   4126 C CG   . GLU A 1 271 ? 20.38900 5.97600  11.53900  1.000 15.50186 ? 276 GLU A CG   1 
ATOM   4127 C CD   . GLU A 1 271 ? 21.48100 6.48500  12.45600  1.000 15.19393 ? 276 GLU A CD   1 
ATOM   4128 O OE1  . GLU A 1 271 ? 22.48100 5.75900  12.68400  1.000 17.36261 ? 276 GLU A OE1  1 
ATOM   4129 O OE2  . GLU A 1 271 ? 21.35700 7.64900  12.89600  1.000 14.78598 ? 276 GLU A OE2  1 
ATOM   4130 H H    . GLU A 1 271 ? 19.28900 4.21600  9.74700   1.000 16.69000 ? 276 GLU A H    1 
ATOM   4131 H HA   . GLU A 1 271 ? 19.01800 6.80900  9.37300   1.000 17.25000 ? 276 GLU A HA   1 
ATOM   4132 H HB2  . GLU A 1 271 ? 21.40000 5.37300  9.86300   1.000 17.80000 ? 276 GLU A HB2  1 
ATOM   4133 H HB3  . GLU A 1 271 ? 21.27100 6.95300  9.97000   1.000 17.80000 ? 276 GLU A HB3  1 
ATOM   4134 H HG2  . GLU A 1 271 ? 19.58600 6.49700  11.69500  1.000 18.61000 ? 276 GLU A HG2  1 
ATOM   4135 H HG3  . GLU A 1 271 ? 20.22300 5.04200  11.74500  1.000 18.61000 ? 276 GLU A HG3  1 
ATOM   4136 N N    . ALA A 1 272 ? 20.44300 5.17600  7.02500   1.000 15.10707 ? 277 ALA A N    1 
ATOM   4137 C CA   . ALA A 1 272 ? 20.90200 5.27000  5.63900   1.000 15.58608 ? 277 ALA A CA   1 
ATOM   4138 C C    . ALA A 1 272 ? 19.80800 5.81500  4.73600   1.000 15.30447 ? 277 ALA A C    1 
ATOM   4139 O O    . ALA A 1 272 ? 20.08500 6.57500  3.80300   1.000 15.69136 ? 277 ALA A O    1 
ATOM   4140 C CB   . ALA A 1 272 ? 21.33000 3.90300  5.12700   1.000 17.12574 ? 277 ALA A CB   1 
ATOM   4141 H H    . ALA A 1 272 ? 20.45200 4.38000  7.35100   1.000 18.14000 ? 277 ALA A H    1 
ATOM   4142 H HA   . ALA A 1 272 ? 21.66600 5.86800  5.61600   1.000 18.71000 ? 277 ALA A HA   1 
ATOM   4143 H HB1  . ALA A 1 272 ? 21.65600 3.99400  4.21800   1.000 20.56000 ? 277 ALA A HB1  1 
ATOM   4144 H HB2  . ALA A 1 272 ? 22.03400 3.55800  5.69800   1.000 20.56000 ? 277 ALA A HB2  1 
ATOM   4145 H HB3  . ALA A 1 272 ? 20.56600 3.30500  5.14700   1.000 20.56000 ? 277 ALA A HB3  1 
ATOM   4146 N N    . VAL A 1 273 ? 18.55400 5.43200  4.99200   1.000 14.88336 ? 278 VAL A N    1 
ATOM   4147 C CA   . VAL A 1 273 ? 17.46600 5.94500  4.17100   1.000 15.02022 ? 278 VAL A CA   1 
ATOM   4148 C C    . VAL A 1 273 ? 17.31300 7.44200  4.37900   1.000 14.08327 ? 278 VAL A C    1 
ATOM   4149 O O    . VAL A 1 273 ? 17.04300 8.19500  3.43400   1.000 14.65439 ? 278 VAL A O    1 
ATOM   4150 C CB   . VAL A 1 273 ? 16.18200 5.16800  4.49400   1.000 16.40723 ? 278 VAL A CB   1 
ATOM   4151 C CG1  . VAL A 1 273 ? 14.96000 5.87800  3.95600   1.000 17.47578 ? 278 VAL A CG1  1 
ATOM   4152 C CG2  . VAL A 1 273 ? 16.26300 3.74000  3.97000   1.000 18.62855 ? 278 VAL A CG2  1 
ATOM   4153 H H    . VAL A 1 273 ? 18.31700 4.89100  5.61700   1.000 17.86000 ? 278 VAL A H    1 
ATOM   4154 H HA   . VAL A 1 273 ? 17.66900 5.80800  3.23300   1.000 18.03000 ? 278 VAL A HA   1 
ATOM   4155 H HB   . VAL A 1 273 ? 16.09100 5.12500  5.45800   1.000 19.70000 ? 278 VAL A HB   1 
ATOM   4156 H HG11 . VAL A 1 273 ? 14.21100 5.26100  3.95700   1.000 20.98000 ? 278 VAL A HG11 1 
ATOM   4157 H HG12 . VAL A 1 273 ? 14.76200 6.63900  4.52300   1.000 20.98000 ? 278 VAL A HG12 1 
ATOM   4158 H HG13 . VAL A 1 273 ? 15.14100 6.17700  3.05200   1.000 20.98000 ? 278 VAL A HG13 1 
ATOM   4159 H HG21 . VAL A 1 273 ? 15.52600 3.22700  4.33800   1.000 22.36000 ? 278 VAL A HG21 1 
ATOM   4160 H HG22 . VAL A 1 273 ? 16.20400 3.75500  3.00200   1.000 22.36000 ? 278 VAL A HG22 1 
ATOM   4161 H HG23 . VAL A 1 273 ? 17.10700 3.35000  4.24400   1.000 22.36000 ? 278 VAL A HG23 1 
ATOM   4162 N N    . ILE A 1 274 ? 17.46700 7.90300  5.62600   1.000 13.16737 ? 279 ILE A N    1 
ATOM   4163 C CA   . ILE A 1 274 ? 17.37400 9.33400  5.88800   1.000 13.95167 ? 279 ILE A CA   1 
ATOM   4164 C C    . ILE A 1 274 ? 18.47300 10.07700 5.14300   1.000 13.32265 ? 279 ILE A C    1 
ATOM   4165 O O    . ILE A 1 274 ? 18.22200 11.10800 4.50800   1.000 13.30949 ? 279 ILE A O    1 
ATOM   4166 C CB   . ILE A 1 274 ? 17.37500 9.63200  7.40100   1.000 13.46477 ? 279 ILE A CB   1 
ATOM   4167 C CG1  . ILE A 1 274 ? 16.11500 9.05300  8.04000   1.000 13.13315 ? 279 ILE A CG1  1 
ATOM   4168 C CG2  . ILE A 1 274 ? 17.52600 11.11300 7.64100   1.000 13.91219 ? 279 ILE A CG2  1 
ATOM   4169 C CD1  . ILE A 1 274 ? 16.06300 9.14100  9.56200   1.000 13.95430 ? 279 ILE A CD1  1 
ATOM   4170 H H    . ILE A 1 274 ? 17.62300 7.41700  6.31800   1.000 15.81000 ? 279 ILE A H    1 
ATOM   4171 H HA   . ILE A 1 274 ? 16.52300 9.65000  5.54700   1.000 16.75000 ? 279 ILE A HA   1 
ATOM   4172 H HB   . ILE A 1 274 ? 18.13600 9.20200  7.82100   1.000 16.17000 ? 279 ILE A HB   1 
ATOM   4173 H HG12 . ILE A 1 274 ? 15.34700 9.53500  7.69500   1.000 15.77000 ? 279 ILE A HG12 1 
ATOM   4174 H HG13 . ILE A 1 274 ? 16.05400 8.11500  7.80100   1.000 15.77000 ? 279 ILE A HG13 1 
ATOM   4175 H HG21 . ILE A 1 274 ? 17.37600 11.29800 8.58200   1.000 16.70000 ? 279 ILE A HG21 1 
ATOM   4176 H HG22 . ILE A 1 274 ? 18.42300 11.38400 7.39100   1.000 16.70000 ? 279 ILE A HG22 1 
ATOM   4177 H HG23 . ILE A 1 274 ? 16.87500 11.58900 7.10200   1.000 16.70000 ? 279 ILE A HG23 1 
ATOM   4178 H HD11 . ILE A 1 274 ? 15.30300 8.63000  9.88200   1.000 16.75000 ? 279 ILE A HD11 1 
ATOM   4179 H HD12 . ILE A 1 274 ? 16.88400 8.77600  9.92800   1.000 16.75000 ? 279 ILE A HD12 1 
ATOM   4180 H HD13 . ILE A 1 274 ? 15.96900 10.07100 9.82200   1.000 16.75000 ? 279 ILE A HD13 1 
ATOM   4181 N N    . ALA A 1 275 ? 19.71400 9.57900  5.23100   1.000 13.79376 ? 280 ALA A N    1 
ATOM   4182 C CA   . ALA A 1 275 ? 20.82500 10.20200 4.50800   1.000 14.38330 ? 280 ALA A CA   1 
ATOM   4183 C C    . ALA A 1 275 ? 20.56800 10.20600 3.01000   1.000 14.37541 ? 280 ALA A C    1 
ATOM   4184 O O    . ALA A 1 275 ? 20.82100 11.20900 2.33700   1.000 14.23329 ? 280 ALA A O    1 
ATOM   4185 C CB   . ALA A 1 275 ? 22.12500 9.45500  4.80900   1.000 14.81493 ? 280 ALA A CB   1 
ATOM   4186 H H    . ALA A 1 275 ? 19.93400 8.89000  5.69700   1.000 16.56000 ? 280 ALA A H    1 
ATOM   4187 H HA   . ALA A 1 275 ? 20.91700 11.12000 4.80800   1.000 17.27000 ? 280 ALA A HA   1 
ATOM   4188 H HB1  . ALA A 1 275 ? 22.85000 9.87400  4.32100   1.000 17.79000 ? 280 ALA A HB1  1 
ATOM   4189 H HB2  . ALA A 1 275 ? 22.29900 9.49700  5.76200   1.000 17.79000 ? 280 ALA A HB2  1 
ATOM   4190 H HB3  . ALA A 1 275 ? 22.02900 8.53000  4.53100   1.000 17.79000 ? 280 ALA A HB3  1 
ATOM   4191 N N    . ALA A 1 276 ? 20.06800 9.09300  2.47700   1.000 14.13064 ? 281 ALA A N    1 
ATOM   4192 C CA   . ALA A 1 276 ? 19.81400 8.99800  1.03900   1.000 14.39909 ? 281 ALA A CA   1 
ATOM   4193 C C    . ALA A 1 276 ? 18.72700 9.97200  0.59900   1.000 14.33330 ? 281 ALA A C    1 
ATOM   4194 O O    . ALA A 1 276 ? 18.81900 10.58000 -0.47700  1.000 15.33079 ? 281 ALA A O    1 
ATOM   4195 C CB   . ALA A 1 276 ? 19.44600 7.56300  0.67300   1.000 15.12287 ? 281 ALA A CB   1 
ATOM   4196 H H    . ALA A 1 276 ? 19.86800 8.38400  2.92100   1.000 16.97000 ? 281 ALA A H    1 
ATOM   4197 H HA   . ALA A 1 276 ? 20.62500 9.23100  0.56000   1.000 17.28000 ? 281 ALA A HA   1 
ATOM   4198 H HB1  . ALA A 1 276 ? 19.28000 7.51300  -0.28100  1.000 18.16000 ? 281 ALA A HB1  1 
ATOM   4199 H HB2  . ALA A 1 276 ? 20.18200 6.97700  0.91200   1.000 18.16000 ? 281 ALA A HB2  1 
ATOM   4200 H HB3  . ALA A 1 276 ? 18.64800 7.30700  1.16200   1.000 18.16000 ? 281 ALA A HB3  1 
ATOM   4201 N N    . ALA A 1 277 ? 17.69200 10.13300 1.42200   1.000 14.23592 ? 282 ALA A N    1 
ATOM   4202 C CA   . ALA A 1 277 ? 16.64000 11.08200 1.09900   1.000 13.80955 ? 282 ALA A CA   1 
ATOM   4203 C C    . ALA A 1 277 ? 17.16600 12.50600 1.11200   1.000 13.56742 ? 282 ALA A C    1 
ATOM   4204 O O    . ALA A 1 277 ? 16.79600 13.31500 0.25200   1.000 13.71480 ? 282 ALA A O    1 
ATOM   4205 C CB   . ALA A 1 277 ? 15.49900 10.91400 2.10300   1.000 13.72270 ? 282 ALA A CB   1 
ATOM   4206 H H    . ALA A 1 277 ? 17.58000 9.71000  2.16200   1.000 17.09000 ? 282 ALA A H    1 
ATOM   4207 H HA   . ALA A 1 277 ? 16.29800 10.90500 0.20800   1.000 16.58000 ? 282 ALA A HA   1 
ATOM   4208 H HB1  . ALA A 1 277 ? 14.80500 11.56200 1.90400   1.000 16.47000 ? 282 ALA A HB1  1 
ATOM   4209 H HB2  . ALA A 1 277 ? 15.14200 10.01500 2.02700   1.000 16.47000 ? 282 ALA A HB2  1 
ATOM   4210 H HB3  . ALA A 1 277 ? 15.84200 11.06000 2.99800   1.000 16.47000 ? 282 ALA A HB3  1 
ATOM   4211 N N    . ALA A 1 278 ? 18.03200 12.83200 2.07600   1.000 14.79651 ? 283 ALA A N    1 
ATOM   4212 C CA   . ALA A 1 278 ? 18.64400 14.15200 2.09600   1.000 13.92799 ? 283 ALA A CA   1 
ATOM   4213 C C    . ALA A 1 278 ? 19.48700 14.38800 0.84900   1.000 14.67281 ? 283 ALA A C    1 
ATOM   4214 O O    . ALA A 1 278 ? 19.49000 15.49500 0.29600   1.000 15.24130 ? 283 ALA A O    1 
ATOM   4215 C CB   . ALA A 1 278 ? 19.51500 14.27000 3.34900   1.000 15.15971 ? 283 ALA A CB   1 
ATOM   4216 H H    . ALA A 1 278 ? 18.27500 12.31300 2.71700   1.000 17.76000 ? 283 ALA A H    1 
ATOM   4217 H HA   . ALA A 1 278 ? 17.95000 14.82900 2.12100   1.000 16.72000 ? 283 ALA A HA   1 
ATOM   4218 H HB1  . ALA A 1 278 ? 19.91900 15.15200 3.37000   1.000 18.20000 ? 283 ALA A HB1  1 
ATOM   4219 H HB2  . ALA A 1 278 ? 18.96000 14.14200 4.13300   1.000 18.20000 ? 283 ALA A HB2  1 
ATOM   4220 H HB3  . ALA A 1 278 ? 20.20700 13.59100 3.31800   1.000 18.20000 ? 283 ALA A HB3  1 
ATOM   4221 N N    A ARG A 1 279 ? 20.21200 13.35800 0.40000   0.330 14.75966 ? 284 ARG A N    1 
ATOM   4222 N N    B ARG A 1 279 ? 20.24100 13.37300 0.41200   0.670 14.22539 ? 284 ARG A N    1 
ATOM   4223 C CA   A ARG A 1 279 ? 21.02500 13.48100 -0.80900  0.330 15.38342 ? 284 ARG A CA   1 
ATOM   4224 C CA   B ARG A 1 279 ? 21.01600 13.53200 -0.81500  0.670 14.70439 ? 284 ARG A CA   1 
ATOM   4225 C C    A ARG A 1 279 ? 20.15400 13.75500 -2.02700  0.330 15.32815 ? 284 ARG A C    1 
ATOM   4226 C C    B ARG A 1 279 ? 20.10400 13.83700 -1.99100  0.670 15.41237 ? 284 ARG A C    1 
ATOM   4227 O O    A ARG A 1 279 ? 20.52800 14.53900 -2.90600  0.330 15.45185 ? 284 ARG A O    1 
ATOM   4228 O O    B ARG A 1 279 ? 20.38700 14.73800 -2.78800  0.670 16.08351 ? 284 ARG A O    1 
ATOM   4229 C CB   A ARG A 1 279 ? 21.84000 12.19900 -1.01700  0.330 16.63094 ? 284 ARG A CB   1 
ATOM   4230 C CB   B ARG A 1 279 ? 21.83300 12.26800 -1.10600  0.670 15.68872 ? 284 ARG A CB   1 
ATOM   4231 C CG   A ARG A 1 279 ? 22.72000 12.17900 -2.27400  0.330 17.99163 ? 284 ARG A CG   1 
ATOM   4232 C CG   B ARG A 1 279 ? 23.00600 12.07000 -0.17900  0.670 17.23628 ? 284 ARG A CG   1 
ATOM   4233 C CD   A ARG A 1 279 ? 23.27100 10.76700 -2.56100  0.330 19.74710 ? 284 ARG A CD   1 
ATOM   4234 C CD   B ARG A 1 279 ? 23.92000 10.95300 -0.65000  0.670 17.80740 ? 284 ARG A CD   1 
ATOM   4235 N NE   A ARG A 1 279 ? 23.81400 10.62100 -3.91200  0.330 21.78682 ? 284 ARG A NE   1 
ATOM   4236 N NE   B ARG A 1 279 ? 24.79000 10.56700 0.44800   0.670 18.92069 ? 284 ARG A NE   1 
ATOM   4237 C CZ   A ARG A 1 279 ? 24.98500 10.07200 -4.21300  0.330 22.97644 ? 284 ARG A CZ   1 
ATOM   4238 C CZ   B ARG A 1 279 ? 24.51200 9.59500  1.30200   0.670 19.89712 ? 284 ARG A CZ   1 
ATOM   4239 N NH1  A ARG A 1 279 ? 25.77900 9.57000  -3.27900  0.330 23.20805 ? 284 ARG A NH1  1 
ATOM   4240 N NH1  B ARG A 1 279 ? 23.51000 8.75500  1.09000   0.670 18.95490 ? 284 ARG A NH1  1 
ATOM   4241 N NH2  A ARG A 1 279 ? 25.36600 10.01500 -5.48600  0.330 23.89497 ? 284 ARG A NH2  1 
ATOM   4242 N NH2  B ARG A 1 279 ? 25.25300 9.46600  2.39900   0.670 20.85250 ? 284 ARG A NH2  1 
ATOM   4243 H H    A ARG A 1 279 ? 20.25000 12.58400 0.77400   0.330 17.72000 ? 284 ARG A H    1 
ATOM   4244 H H    B ARG A 1 279 ? 20.31600 12.60800 0.79600   0.670 17.08000 ? 284 ARG A H    1 
ATOM   4245 H HA   A ARG A 1 279 ? 21.64200 14.22200 -0.70300  0.330 18.47000 ? 284 ARG A HA   1 
ATOM   4246 H HA   B ARG A 1 279 ? 21.63700 14.26800 -0.69500  0.670 17.65000 ? 284 ARG A HA   1 
ATOM   4247 H HB2  A ARG A 1 279 ? 22.42400 12.08000 -0.25200  0.330 19.96000 ? 284 ARG A HB2  1 
ATOM   4248 H HB2  B ARG A 1 279 ? 21.25200 11.49600 -1.01700  0.670 18.83000 ? 284 ARG A HB2  1 
ATOM   4249 H HB3  A ARG A 1 279 ? 21.22400 11.45200 -1.08300  0.330 19.96000 ? 284 ARG A HB3  1 
ATOM   4250 H HB3  B ARG A 1 279 ? 22.17700 12.32200 -2.01100  0.670 18.83000 ? 284 ARG A HB3  1 
ATOM   4251 H HG2  A ARG A 1 279 ? 22.19400 12.46100 -3.03800  0.330 21.60000 ? 284 ARG A HG2  1 
ATOM   4252 H HG2  B ARG A 1 279 ? 23.52400 12.88900 -0.13900  0.670 20.69000 ? 284 ARG A HG2  1 
ATOM   4253 H HG3  A ARG A 1 279 ? 23.47100 12.77900 -2.14800  0.330 21.60000 ? 284 ARG A HG3  1 
ATOM   4254 H HG3  B ARG A 1 279 ? 22.67900 11.84100 0.70600   0.670 20.69000 ? 284 ARG A HG3  1 
ATOM   4255 H HD2  A ARG A 1 279 ? 23.98400 10.57400 -1.93200  0.330 23.70000 ? 284 ARG A HD2  1 
ATOM   4256 H HD2  B ARG A 1 279 ? 23.39200 10.18500 -0.92100  0.670 21.37000 ? 284 ARG A HD2  1 
ATOM   4257 H HD3  A ARG A 1 279 ? 22.55400 10.12200 -2.45700  0.330 23.70000 ? 284 ARG A HD3  1 
ATOM   4258 H HD3  B ARG A 1 279 ? 24.46300 11.26100 -1.39200  0.670 21.37000 ? 284 ARG A HD3  1 
ATOM   4259 H HE   A ARG A 1 279 ? 23.33600 10.91500 -4.56400  0.330 26.15000 ? 284 ARG A HE   1 
ATOM   4260 H HE   B ARG A 1 279 ? 25.53000 10.99500 0.54800   0.670 22.71000 ? 284 ARG A HE   1 
ATOM   4261 H HH11 A ARG A 1 279 ? 25.54100 9.59400  -2.45300  0.330 27.86000 ? 284 ARG A HH11 1 
ATOM   4262 H HH11 B ARG A 1 279 ? 23.02400 8.83500  0.38500   0.670 22.75000 ? 284 ARG A HH11 1 
ATOM   4263 H HH12 A ARG A 1 279 ? 26.53300 9.21900  -3.49900  0.330 27.86000 ? 284 ARG A HH12 1 
ATOM   4264 H HH12 B ARG A 1 279 ? 23.34500 8.13000  1.65700   0.670 22.75000 ? 284 ARG A HH12 1 
ATOM   4265 H HH21 A ARG A 1 279 ? 24.85600 10.33100 -6.10200  0.330 28.68000 ? 284 ARG A HH21 1 
ATOM   4266 H HH21 B ARG A 1 279 ? 25.90300 10.01000 2.54500   0.670 25.03000 ? 284 ARG A HH21 1 
ATOM   4267 H HH22 A ARG A 1 279 ? 26.12200 9.66200  -5.69300  0.330 28.68000 ? 284 ARG A HH22 1 
ATOM   4268 H HH22 B ARG A 1 279 ? 25.08200 8.83900  2.96200   0.670 25.03000 ? 284 ARG A HH22 1 
ATOM   4269 N N    . LEU A 1 280 ? 18.99400 13.10200 -2.10100  1.000 15.16761 ? 285 LEU A N    1 
ATOM   4270 C CA   . LEU A 1 280 ? 18.07200 13.34900 -3.20100  1.000 15.37553 ? 285 LEU A CA   1 
ATOM   4271 C C    . LEU A 1 280 ? 17.49200 14.75700 -3.13000  1.000 16.28090 ? 285 LEU A C    1 
ATOM   4272 O O    . LEU A 1 280 ? 17.27400 15.40000 -4.16300  1.000 16.88887 ? 285 LEU A O    1 
ATOM   4273 C CB   . LEU A 1 280 ? 16.95000 12.30700 -3.21500  1.000 15.75715 ? 285 LEU A CB   1 
ATOM   4274 C CG   . LEU A 1 280 ? 17.33200 10.89800 -3.66500  1.000 18.01269 ? 285 LEU A CG   1 
ATOM   4275 C CD1  . LEU A 1 280 ? 16.12300 9.96700  -3.54900  1.000 19.82080 ? 285 LEU A CD1  1 
ATOM   4276 C CD2  . LEU A 1 280 ? 17.89300 10.92900 -5.09100  1.000 18.49695 ? 285 LEU A CD2  1 
ATOM   4277 H H    A LEU A 1 280 ? 18.72200 12.51800 -1.53100  0.330 18.21000 ? 285 LEU A H    1 
ATOM   4278 H H    B LEU A 1 280 ? 18.76100 12.47200 -1.56400  0.670 18.21000 ? 285 LEU A H    1 
ATOM   4279 H HA   . LEU A 1 280 ? 18.56200 13.26100 -4.03300  1.000 18.46000 ? 285 LEU A HA   1 
ATOM   4280 H HB2  . LEU A 1 280 ? 16.59800 12.23200 -2.31400  1.000 18.92000 ? 285 LEU A HB2  1 
ATOM   4281 H HB3  . LEU A 1 280 ? 16.25600 12.62000 -3.81600  1.000 18.92000 ? 285 LEU A HB3  1 
ATOM   4282 H HG   . LEU A 1 280 ? 18.03000 10.54300 -3.09200  1.000 21.62000 ? 285 LEU A HG   1 
ATOM   4283 H HD11 . LEU A 1 280 ? 16.38300 9.07500  -3.82700  1.000 23.79000 ? 285 LEU A HD11 1 
ATOM   4284 H HD12 . LEU A 1 280 ? 15.82200 9.95300  -2.62700  1.000 23.79000 ? 285 LEU A HD12 1 
ATOM   4285 H HD13 . LEU A 1 280 ? 15.41400 10.29800 -4.12300  1.000 23.79000 ? 285 LEU A HD13 1 
ATOM   4286 H HD21 . LEU A 1 280 ? 17.91400 10.02500 -5.44200  1.000 22.21000 ? 285 LEU A HD21 1 
ATOM   4287 H HD22 . LEU A 1 280 ? 17.32000 11.48500 -5.64300  1.000 22.21000 ? 285 LEU A HD22 1 
ATOM   4288 H HD23 . LEU A 1 280 ? 18.79000 11.29700 -5.06900  1.000 22.21000 ? 285 LEU A HD23 1 
ATOM   4289 N N    . ALA A 1 281 ? 17.18900 15.23700 -1.92200  1.000 15.35974 ? 286 ALA A N    1 
ATOM   4290 C CA   . ALA A 1 281 ? 16.67200 16.59300 -1.77700  1.000 15.55186 ? 286 ALA A CA   1 
ATOM   4291 C C    . ALA A 1 281 ? 17.68000 17.62600 -2.26200  1.000 15.30447 ? 286 ALA A C    1 
ATOM   4292 O O    . ALA A 1 281 ? 17.33900 18.55800 -3.00000  1.000 15.63082 ? 286 ALA A O    1 
ATOM   4293 C CB   . ALA A 1 281 ? 16.26100 16.84400 -0.31700  1.000 15.94139 ? 286 ALA A CB   1 
ATOM   4294 H H    . ALA A 1 281 ? 17.27200 14.80400 -1.18400  1.000 18.44000 ? 286 ALA A H    1 
ATOM   4295 H HA   . ALA A 1 281 ? 15.87700 16.68900 -2.32500  1.000 18.67000 ? 286 ALA A HA   1 
ATOM   4296 H HB1  . ALA A 1 281 ? 15.92300 17.75000 -0.23600  1.000 19.14000 ? 286 ALA A HB1  1 
ATOM   4297 H HB2  . ALA A 1 281 ? 15.57000 16.21000 -0.07000  1.000 19.14000 ? 286 ALA A HB2  1 
ATOM   4298 H HB3  . ALA A 1 281 ? 17.03700 16.72800 0.25300   1.000 19.14000 ? 286 ALA A HB3  1 
ATOM   4299 N N    . LEU A 1 282 ? 18.93500 17.47500 -1.85700  1.000 16.41513 ? 287 LEU A N    1 
ATOM   4300 C CA   . LEU A 1 282 ? 19.95000 18.41200 -2.30900  1.000 17.28365 ? 287 LEU A CA   1 
ATOM   4301 C C    . LEU A 1 282 ? 20.13300 18.33300 -3.82300  1.000 17.48894 ? 287 LEU A C    1 
ATOM   4302 O O    . LEU A 1 282 ? 20.30300 19.35900 -4.48800  1.000 17.59421 ? 287 LEU A O    1 
ATOM   4303 C CB   . LEU A 1 282 ? 21.26300 18.13200 -1.56900  1.000 18.73909 ? 287 LEU A CB   1 
ATOM   4304 C CG   . LEU A 1 282 ? 21.20400 18.41300 -0.05900  1.000 20.51562 ? 287 LEU A CG   1 
ATOM   4305 C CD1  . LEU A 1 282 ? 22.49000 17.98100 0.64100   1.000 21.51311 ? 287 LEU A CD1  1 
ATOM   4306 C CD2  . LEU A 1 282 ? 20.93300 19.88300 0.18900   1.000 21.64470 ? 287 LEU A CD2  1 
ATOM   4307 H H    . LEU A 1 282 ? 19.21800 16.85400 -1.33400  1.000 19.71000 ? 287 LEU A H    1 
ATOM   4308 H HA   . LEU A 1 282 ? 19.67800 19.31900 -2.09900  1.000 20.75000 ? 287 LEU A HA   1 
ATOM   4309 H HB2  . LEU A 1 282 ? 21.49200 17.19600 -1.68700  1.000 22.50000 ? 287 LEU A HB2  1 
ATOM   4310 H HB3  . LEU A 1 282 ? 21.95800 18.69300 -1.94700  1.000 22.50000 ? 287 LEU A HB3  1 
ATOM   4311 H HG   . LEU A 1 282 ? 20.47800 17.89400 0.32200   1.000 24.62000 ? 287 LEU A HG   1 
ATOM   4312 H HD11 . LEU A 1 282 ? 22.40400 18.15200 1.59200   1.000 25.82000 ? 287 LEU A HD11 1 
ATOM   4313 H HD12 . LEU A 1 282 ? 22.63200 17.03400 0.48600   1.000 25.82000 ? 287 LEU A HD12 1 
ATOM   4314 H HD13 . LEU A 1 282 ? 23.23200 18.49100 0.28000   1.000 25.82000 ? 287 LEU A HD13 1 
ATOM   4315 H HD21 . LEU A 1 282 ? 21.10000 20.08100 1.12400   1.000 25.98000 ? 287 LEU A HD21 1 
ATOM   4316 H HD22 . LEU A 1 282 ? 21.52300 20.41200 -0.37100  1.000 25.98000 ? 287 LEU A HD22 1 
ATOM   4317 H HD23 . LEU A 1 282 ? 20.00800 20.07600 -0.03000  1.000 25.98000 ? 287 LEU A HD23 1 
ATOM   4318 N N    . GLU A 1 283 ? 20.12400 17.12000 -4.37700  1.000 17.16785 ? 288 GLU A N    1 
ATOM   4319 C CA   . GLU A 1 283 ? 20.23100 16.96400 -5.82700  1.000 18.26272 ? 288 GLU A CA   1 
ATOM   4320 C C    . GLU A 1 283 ? 19.06400 17.65100 -6.51900  1.000 18.28903 ? 288 GLU A C    1 
ATOM   4321 O O    . GLU A 1 283 ? 19.25700 18.36400 -7.50000  1.000 18.53643 ? 288 GLU A O    1 
ATOM   4322 C CB   . GLU A 1 283 ? 20.28400 15.48100 -6.17900  1.000 19.97082 ? 288 GLU A CB   1 
ATOM   4323 C CG   . GLU A 1 283 ? 20.31900 15.18500 -7.66200  1.000 25.06090 ? 288 GLU A CG   1 
ATOM   4324 C CD   . GLU A 1 283 ? 20.10900 13.71500 -7.94600  1.000 29.40879 ? 288 GLU A CD   1 
ATOM   4325 O OE1  . GLU A 1 283 ? 20.66400 12.88500 -7.19900  1.000 31.90909 ? 288 GLU A OE1  1 
ATOM   4326 O OE2  . GLU A 1 283 ? 19.37800 13.38800 -8.90500  1.000 31.54062 ? 288 GLU A OE2  1 
ATOM   4327 H H    . GLU A 1 283 ? 20.05800 16.38100 -3.94300  1.000 20.61000 ? 288 GLU A H    1 
ATOM   4328 H HA   . GLU A 1 283 ? 21.05100 17.37200 -6.14500  1.000 21.92000 ? 288 GLU A HA   1 
ATOM   4329 H HB2  . GLU A 1 283 ? 21.08500 15.10000 -5.78500  1.000 23.98000 ? 288 GLU A HB2  1 
ATOM   4330 H HB3  . GLU A 1 283 ? 19.49700 15.04900 -5.81300  1.000 23.98000 ? 288 GLU A HB3  1 
ATOM   4331 H HG2  . GLU A 1 283 ? 19.61500 15.68400 -8.10500  1.000 30.08000 ? 288 GLU A HG2  1 
ATOM   4332 H HG3  . GLU A 1 283 ? 21.18400 15.44300 -8.02000  1.000 30.08000 ? 288 GLU A HG3  1 
ATOM   4333 N N    . GLY A 1 284 ? 17.85100 17.49400 -5.98400  1.000 18.01005 ? 289 GLY A N    1 
ATOM   4334 C CA   . GLY A 1 284 ? 16.70500 18.14700 -6.59300  1.000 17.97584 ? 289 GLY A CA   1 
ATOM   4335 C C    . GLY A 1 284 ? 16.83700 19.65600 -6.59400  1.000 17.43104 ? 289 GLY A C    1 
ATOM   4336 O O    . GLY A 1 284 ? 16.42700 20.32700 -7.53700  1.000 19.19967 ? 289 GLY A O    1 
ATOM   4337 H H    . GLY A 1 284 ? 17.67400 17.02600 -5.28500  1.000 21.62000 ? 289 GLY A H    1 
ATOM   4338 H HA2  . GLY A 1 284 ? 16.61500 17.84700 -7.51000  1.000 21.58000 ? 289 GLY A HA2  1 
ATOM   4339 H HA3  . GLY A 1 284 ? 15.90300 17.91000 -6.10200  1.000 21.58000 ? 289 GLY A HA3  1 
ATOM   4340 N N    . LEU A 1 285 ? 17.42100 20.21400 -5.54400  1.000 17.00730 ? 290 LEU A N    1 
ATOM   4341 C CA   . LEU A 1 285 ? 17.59800 21.65600 -5.46000  1.000 17.01520 ? 290 LEU A CA   1 
ATOM   4342 C C    . LEU A 1 285 ? 18.76900 22.15500 -6.29600  1.000 18.49169 ? 290 LEU A C    1 
ATOM   4343 O O    . LEU A 1 285 ? 18.94200 23.36900 -6.42500  1.000 19.36022 ? 290 LEU A O    1 
ATOM   4344 C CB   . LEU A 1 285 ? 17.81800 22.05400 -3.99800  1.000 16.02297 ? 290 LEU A CB   1 
ATOM   4345 C CG   . LEU A 1 285 ? 16.58800 21.96200 -3.10200  1.000 15.96770 ? 290 LEU A CG   1 
ATOM   4346 C CD1  . LEU A 1 285 ? 16.97200 22.33400 -1.68200  1.000 15.96244 ? 290 LEU A CD1  1 
ATOM   4347 C CD2  . LEU A 1 285 ? 15.47500 22.86800 -3.63400  1.000 16.98888 ? 290 LEU A CD2  1 
ATOM   4348 H H    . LEU A 1 285 ? 17.72500 19.77900 -4.86700  1.000 20.42000 ? 290 LEU A H    1 
ATOM   4349 H HA   . LEU A 1 285 ? 16.79400 22.09400 -5.78200  1.000 20.43000 ? 290 LEU A HA   1 
ATOM   4350 H HB2  . LEU A 1 285 ? 18.49400 21.46900 -3.62200  1.000 19.23000 ? 290 LEU A HB2  1 
ATOM   4351 H HB3  . LEU A 1 285 ? 18.12500 22.97400 -3.97500  1.000 19.23000 ? 290 LEU A HB3  1 
ATOM   4352 H HG   . LEU A 1 285 ? 16.24300 21.05500 -3.09700  1.000 19.17000 ? 290 LEU A HG   1 
ATOM   4353 H HD11 . LEU A 1 285 ? 16.18500 22.28100 -1.11800  1.000 19.16000 ? 290 LEU A HD11 1 
ATOM   4354 H HD12 . LEU A 1 285 ? 17.64800 21.71500 -1.36500  1.000 19.16000 ? 290 LEU A HD12 1 
ATOM   4355 H HD13 . LEU A 1 285 ? 17.32300 23.23900 -1.67700  1.000 19.16000 ? 290 LEU A HD13 1 
ATOM   4356 H HD21 . LEU A 1 285 ? 14.82800 23.02000 -2.92900  1.000 20.39000 ? 290 LEU A HD21 1 
ATOM   4357 H HD22 . LEU A 1 285 ? 15.86300 23.71100 -3.91600  1.000 20.39000 ? 290 LEU A HD22 1 
ATOM   4358 H HD23 . LEU A 1 285 ? 15.04700 22.43200 -4.38800  1.000 20.39000 ? 290 LEU A HD23 1 
ATOM   4359 N N    . GLY A 1 286 ? 19.56700 21.25600 -6.86700  1.000 19.47865 ? 291 GLY A N    1 
ATOM   4360 C CA   . GLY A 1 286 ? 20.69300 21.67100 -7.68300  1.000 20.62089 ? 291 GLY A CA   1 
ATOM   4361 C C    . GLY A 1 286 ? 21.88400 22.11200 -6.87500  1.000 21.45257 ? 291 GLY A C    1 
ATOM   4362 O O    . GLY A 1 286 ? 22.74000 22.84100 -7.38000  1.000 23.49229 ? 291 GLY A O    1 
ATOM   4363 H H    . GLY A 1 286 ? 19.47500 20.40400 -6.79500  1.000 23.38000 ? 291 GLY A H    1 
ATOM   4364 H HA2  . GLY A 1 286 ? 20.96700 20.92900 -8.24500  1.000 24.75000 ? 291 GLY A HA2  1 
ATOM   4365 H HA3  . GLY A 1 286 ? 20.42000 22.41000 -8.24700  1.000 24.75000 ? 291 GLY A HA3  1 
ATOM   4366 N N    . VAL A 1 287 ? 21.95800 21.67800 -5.62400  1.000 20.84987 ? 292 VAL A N    1 
ATOM   4367 C CA   . VAL A 1 287 ? 23.06500 21.98600 -4.73000  1.000 22.63956 ? 292 VAL A CA   1 
ATOM   4368 C C    . VAL A 1 287 ? 24.14000 20.93500 -4.97500  1.000 23.79759 ? 292 VAL A C    1 
ATOM   4369 O O    . VAL A 1 287 ? 23.95100 19.75300 -4.67200  1.000 24.91615 ? 292 VAL A O    1 
ATOM   4370 C CB   . VAL A 1 287 ? 22.59400 21.99400 -3.26900  1.000 22.90538 ? 292 VAL A CB   1 
ATOM   4371 C CG1  . VAL A 1 287 ? 23.76000 22.22300 -2.33200  1.000 23.91076 ? 292 VAL A CG1  1 
ATOM   4372 C CG2  . VAL A 1 287 ? 21.51400 23.06900 -3.07300  1.000 23.25279 ? 292 VAL A CG2  1 
ATOM   4373 H H    . VAL A 1 287 ? 21.35700 21.18400 -5.25600  1.000 25.03000 ? 292 VAL A H    1 
ATOM   4374 H HA   . VAL A 1 287 ? 23.43800 22.85800 -4.93400  1.000 27.17000 ? 292 VAL A HA   1 
ATOM   4375 H HB   . VAL A 1 287 ? 22.20900 21.13100 -3.05300  1.000 27.49000 ? 292 VAL A HB   1 
ATOM   4376 H HG11 . VAL A 1 287 ? 23.41900 22.45100 -1.45300  1.000 28.70000 ? 292 VAL A HG11 1 
ATOM   4377 H HG12 . VAL A 1 287 ? 24.28800 21.41100 -2.28200  1.000 28.70000 ? 292 VAL A HG12 1 
ATOM   4378 H HG13 . VAL A 1 287 ? 24.30200 22.95100 -2.67500  1.000 28.70000 ? 292 VAL A HG13 1 
ATOM   4379 H HG21 . VAL A 1 287 ? 21.25100 23.08600 -2.13900  1.000 27.91000 ? 292 VAL A HG21 1 
ATOM   4380 H HG22 . VAL A 1 287 ? 21.87700 23.93200 -3.32900  1.000 27.91000 ? 292 VAL A HG22 1 
ATOM   4381 H HG23 . VAL A 1 287 ? 20.74900 22.85300 -3.62800  1.000 27.91000 ? 292 VAL A HG23 1 
ATOM   4382 N N    . ASN A 1 288 ? 25.25600 21.35500 -5.56000  1.000 23.66600 ? 293 ASN A N    1 
ATOM   4383 C CA   . ASN A 1 288 ? 26.34200 20.42100 -5.82600  1.000 23.94761 ? 293 ASN A CA   1 
ATOM   4384 C C    . ASN A 1 288 ? 26.96700 19.99800 -4.50300  1.000 25.78730 ? 293 ASN A C    1 
ATOM   4385 O O    . ASN A 1 288 ? 27.41700 20.84600 -3.72700  1.000 26.60845 ? 293 ASN A O    1 
ATOM   4386 C CB   . ASN A 1 288 ? 27.39400 21.06600 -6.72000  1.000 23.14488 ? 293 ASN A CB   1 
ATOM   4387 C CG   . ASN A 1 288 ? 28.46600 20.08500 -7.13200  1.000 22.01843 ? 293 ASN A CG   1 
ATOM   4388 O OD1  . ASN A 1 288 ? 28.15300 19.04600 -7.71300  1.000 24.39240 ? 293 ASN A OD1  1 
ATOM   4389 N ND2  . ASN A 1 288 ? 29.73100 20.39600 -6.83500  1.000 19.66815 ? 293 ASN A ND2  1 
ATOM   4390 H H    . ASN A 1 288 ? 25.40700 22.16500 -5.80800  1.000 28.41000 ? 293 ASN A H    1 
ATOM   4391 H HA   . ASN A 1 288 ? 25.99500 19.64100 -6.28500  1.000 28.74000 ? 293 ASN A HA   1 
ATOM   4392 H HB2  . ASN A 1 288 ? 26.96700 21.40200 -7.52400  1.000 27.78000 ? 293 ASN A HB2  1 
ATOM   4393 H HB3  . ASN A 1 288 ? 27.81800 21.79400 -6.24000  1.000 27.78000 ? 293 ASN A HB3  1 
ATOM   4394 H HD21 . ASN A 1 288 ? 30.36800 19.86100 -7.05300  1.000 23.61000 ? 293 ASN A HD21 1 
ATOM   4395 H HD22 . ASN A 1 288 ? 29.90800 21.13100 -6.42500  1.000 23.61000 ? 293 ASN A HD22 1 
ATOM   4396 N N    . GLY A 1 289 ? 26.98000 18.69600 -4.23900  1.000 26.95060 ? 294 GLY A N    1 
ATOM   4397 C CA   . GLY A 1 289 ? 27.46500 18.18000 -2.96900  1.000 27.84808 ? 294 GLY A CA   1 
ATOM   4398 C C    . GLY A 1 289 ? 28.38000 16.97700 -3.09800  1.000 27.72438 ? 294 GLY A C    1 
ATOM   4399 O O    . GLY A 1 289 ? 29.33800 16.99200 -3.89200  1.000 28.35340 ? 294 GLY A O    1 
ATOM   4400 H H    . GLY A 1 289 ? 26.71000 18.08800 -4.78500  1.000 32.35000 ? 294 GLY A H    1 
ATOM   4401 H HA2  . GLY A 1 289 ? 27.95600 18.88100 -2.51200  1.000 33.43000 ? 294 GLY A HA2  1 
ATOM   4402 H HA3  . GLY A 1 289 ? 26.70600 17.92000 -2.42400  1.000 33.43000 ? 294 GLY A HA3  1 
HETATM 4403 S S    . SO4 B 2 .   ? 30.30400 32.43300 1.82300   1.000 55.23820 ? 301 SO4 A S    1 
HETATM 4404 O O1   . SO4 B 2 .   ? 30.19200 30.98000 1.76400   1.000 55.00133 ? 301 SO4 A O1   1 
HETATM 4405 O O2   . SO4 B 2 .   ? 30.35000 32.99800 0.47700   1.000 55.24873 ? 301 SO4 A O2   1 
HETATM 4406 O O3   . SO4 B 2 .   ? 31.53000 32.79300 2.52900   1.000 55.95408 ? 301 SO4 A O3   1 
HETATM 4407 O O4   . SO4 B 2 .   ? 29.15800 32.97900 2.54500   1.000 55.84880 ? 301 SO4 A O4   1 
HETATM 4408 S S    . SO4 C 2 .   ? 21.06800 1.87700  9.39700   1.000 28.04284 ? 302 SO4 A S    1 
HETATM 4409 O O1   . SO4 C 2 .   ? 20.50200 0.66800  8.80200   1.000 31.39587 ? 302 SO4 A O1   1 
HETATM 4410 O O2   . SO4 C 2 .   ? 21.35900 2.82200  8.31900   1.000 26.29526 ? 302 SO4 A O2   1 
HETATM 4411 O O3   . SO4 C 2 .   ? 20.09200 2.47200  10.33600  1.000 24.10026 ? 302 SO4 A O3   1 
HETATM 4412 O O4   . SO4 C 2 .   ? 22.27800 1.50000  10.12400  1.000 29.47722 ? 302 SO4 A O4   1 
HETATM 4413 C C1   A O2F D 3 .   ? 19.09700 4.16800  22.53500  0.460 24.68454 ? 303 O2F A C1   1 
HETATM 4414 C C2   A O2F D 3 .   ? 16.90100 3.08500  22.18200  0.460 24.83719 ? 303 O2F A C2   1 
HETATM 4415 C C3   A O2F D 3 .   ? 19.38600 4.59200  19.70100  0.460 21.72892 ? 303 O2F A C3   1 
HETATM 4416 C C4   A O2F D 3 .   ? 18.80500 5.93900  17.84800  0.460 19.89975 ? 303 O2F A C4   1 
HETATM 4417 C C5   A O2F D 3 .   ? 19.79200 6.03000  20.08100  0.460 20.23927 ? 303 O2F A C5   1 
HETATM 4418 C C7   A O2F D 3 .   ? 18.04000 8.66300  21.05500  0.460 13.88324 ? 303 O2F A C7   1 
HETATM 4419 C C9   A O2F D 3 .   ? 18.42100 10.68100 19.50500  0.460 16.93887 ? 303 O2F A C9   1 
HETATM 4420 C C11  A O2F D 3 .   ? 14.82100 9.38600  21.78300  0.460 13.94904 ? 303 O2F A C11  1 
HETATM 4421 C C15  A O2F D 3 .   ? 17.30100 8.64500  22.41200  0.460 13.50688 ? 303 O2F A C15  1 
HETATM 4422 C C16  A O2F D 3 .   ? 16.75300 7.26900  22.78000  0.460 13.79376 ? 303 O2F A C16  1 
HETATM 4423 N N    A O2F D 3 .   ? 18.01300 3.84300  21.61600  0.460 24.27133 ? 303 O2F A N    1 
HETATM 4424 C C    A O2F D 3 .   ? 18.04300 4.20400  20.32200  0.460 23.47650 ? 303 O2F A C    1 
HETATM 4425 O O    A O2F D 3 .   ? 17.03500 4.21800  19.63800  0.460 24.05552 ? 303 O2F A O    1 
HETATM 4426 C C10  A O2F D 3 .   ? 16.23600 9.75400  22.28800  0.460 13.89377 ? 303 O2F A C10  1 
HETATM 4427 C C12  A O2F D 3 .   ? 14.35500 10.42500 20.81600  0.460 14.29645 ? 303 O2F A C12  1 
HETATM 4428 C C13  A O2F D 3 .   ? 13.77500 9.29900  22.89500  0.460 13.62795 ? 303 O2F A C13  1 
HETATM 4429 C C14  A O2F D 3 .   ? 12.52300 8.57600  22.44100  0.460 14.74650 ? 303 O2F A C14  1 
HETATM 4430 C C6   A O2F D 3 .   ? 18.99200 6.88100  19.05300  0.460 18.59433 ? 303 O2F A C6   1 
HETATM 4431 C C8   A O2F D 3 .   ? 17.71400 10.07400 20.64600  0.460 15.47554 ? 303 O2F A C8   1 
HETATM 4432 N N1   A O2F D 3 .   ? 19.30200 4.61000  18.23100  0.460 21.25518 ? 303 O2F A N1   1 
HETATM 4433 N N2   A O2F D 3 .   ? 16.78500 10.67700 21.28100  0.460 15.20972 ? 303 O2F A N2   1 
HETATM 4434 O O1   A O2F D 3 .   ? 19.61400 10.42100 19.26500  0.460 16.59936 ? 303 O2F A O1   1 
HETATM 4435 O O2   A O2F D 3 .   ? 17.69600 11.46300 18.86700  0.460 16.90992 ? 303 O2F A O2   1 
HETATM 4436 O O3   A O2F D 3 .   ? 13.89500 10.20000 19.72200  0.460 15.60713 ? 303 O2F A O3   1 
HETATM 4437 O O4   A O2F D 3 .   ? 14.35400 8.63900  24.02300  0.460 13.62005 ? 303 O2F A O4   1 
HETATM 4438 S S    A O2F D 3 .   ? 17.43100 7.52600  19.75700  0.460 15.22288 ? 303 O2F A S    1 
HETATM 4439 H H7   A O2F D 3 .   ? 20.07100 3.95200  22.09900  0.460 29.63000 ? 303 O2F A H7   1 
HETATM 4440 H H8   A O2F D 3 .   ? 19.09000 5.22300  22.80500  0.460 29.63000 ? 303 O2F A H8   1 
HETATM 4441 H H6   A O2F D 3 .   ? 19.02300 3.59800  23.46000  0.460 29.63000 ? 303 O2F A H6   1 
HETATM 4442 H H11  A O2F D 3 .   ? 16.62700 3.42300  23.18100  0.460 29.81000 ? 303 O2F A H11  1 
HETATM 4443 H H9   A O2F D 3 .   ? 17.12000 2.02200  22.27300  0.460 29.81000 ? 303 O2F A H9   1 
HETATM 4444 H H10  A O2F D 3 .   ? 15.99500 3.15600  21.58200  0.460 29.81000 ? 303 O2F A H10  1 
HETATM 4445 H H    A O2F D 3 .   ? 20.12700 3.86400  20.03000  0.460 26.08000 ? 303 O2F A H    1 
HETATM 4446 H H13  A O2F D 3 .   ? 19.34400 6.28400  16.96600  0.460 23.89000 ? 303 O2F A H13  1 
HETATM 4447 H H14  A O2F D 3 .   ? 17.76300 5.86000  17.54200  0.460 23.89000 ? 303 O2F A H14  1 
HETATM 4448 H H16  A O2F D 3 .   ? 19.53000 6.29400  21.10500  0.460 24.30000 ? 303 O2F A H16  1 
HETATM 4449 H H15  A O2F D 3 .   ? 20.86300 6.21000  19.99900  0.460 24.30000 ? 303 O2F A H15  1 
HETATM 4450 H H2   A O2F D 3 .   ? 19.11200 8.49300  21.14100  0.460 16.67000 ? 303 O2F A H2   1 
HETATM 4451 H H18  A O2F D 3 .   ? 14.94800 8.43800  21.26200  0.460 16.74000 ? 303 O2F A H18  1 
HETATM 4452 H H5   A O2F D 3 .   ? 18.00200 8.95000  23.18700  0.460 16.22000 ? 303 O2F A H5   1 
HETATM 4453 H H25  A O2F D 3 .   ? 16.10400 6.87700  21.99800  0.460 16.56000 ? 303 O2F A H25  1 
HETATM 4454 H H24  A O2F D 3 .   ? 17.55500 6.54900  22.93200  0.460 16.56000 ? 303 O2F A H24  1 
HETATM 4455 H H26  A O2F D 3 .   ? 16.17000 7.30700  23.70000  0.460 16.56000 ? 303 O2F A H26  1 
HETATM 4456 H H3   A O2F D 3 .   ? 16.14300 10.25200 23.25200  0.460 16.68000 ? 303 O2F A H3   1 
HETATM 4457 H H4   A O2F D 3 .   ? 13.48800 10.30000 23.21200  0.460 16.36000 ? 303 O2F A H4   1 
HETATM 4458 H H20  A O2F D 3 .   ? 11.96600 9.15800  21.70800  0.460 17.70000 ? 303 O2F A H20  1 
HETATM 4459 H H22  A O2F D 3 .   ? 11.84900 8.37700  23.27300  0.460 17.70000 ? 303 O2F A H22  1 
HETATM 4460 H H21  A O2F D 3 .   ? 12.75600 7.61800  21.98000  0.460 17.70000 ? 303 O2F A H21  1 
HETATM 4461 H H1   A O2F D 3 .   ? 19.58400 7.74600  18.75600  0.460 22.32000 ? 303 O2F A H1   1 
HETATM 4462 H H12  A O2F D 3 .   ? 20.20600 4.40200  17.81900  0.460 25.52000 ? 303 O2F A H12  1 
HETATM 4463 H H23  A O2F D 3 .   ? 14.04500 7.69500  24.00000  0.460 16.35000 ? 303 O2F A H23  1 
HETATM 4464 C C1   B MER E 4 .   ? 13.96600 10.43400 20.76800  0.540 14.99390 ? 304 MER A C1   1 
HETATM 4465 C C2   B MER E 4 .   ? 18.11500 8.86900  20.58400  0.540 23.89497 ? 304 MER A C2   1 
HETATM 4466 C C3   B MER E 4 .   ? 14.60400 9.30700  21.52100  0.540 17.02836 ? 304 MER A C3   1 
HETATM 4467 C C4   B MER E 4 .   ? 16.11600 9.58600  21.67900  0.540 19.82606 ? 304 MER A C4   1 
HETATM 4468 C C5   B MER E 4 .   ? 17.75400 10.12500 20.11000  0.540 23.83707 ? 304 MER A C5   1 
HETATM 4469 O O6   B MER E 4 .   ? 13.60500 10.36200 19.60800  0.540 15.10707 ? 304 MER A O6   1 
HETATM 4470 C C7   B MER E 4 .   ? 13.94000 9.19600  22.89700  0.540 17.92847 ? 304 MER A C7   1 
HETATM 4471 O O8   B MER E 4 .   ? 14.61300 8.19800  23.67400  0.540 17.91794 ? 304 MER A O8   1 
HETATM 4472 C C9   B MER E 4 .   ? 12.45400 8.91200  22.80000  0.540 19.20493 ? 304 MER A C9   1 
HETATM 4473 N N10  B MER E 4 .   ? 16.59700 10.53300 20.68600  0.540 21.56838 ? 304 MER A N10  1 
HETATM 4474 C C11  B MER E 4 .   ? 18.44900 10.96900 19.09600  0.540 25.68729 ? 304 MER A C11  1 
HETATM 4475 O O12  B MER E 4 .   ? 17.81000 11.92700 18.61300  0.540 26.93744 ? 304 MER A O12  1 
HETATM 4476 O O13  B MER E 4 .   ? 19.63200 10.66900 18.82200  0.540 26.02680 ? 304 MER A O13  1 
HETATM 4477 S S14  B MER E 4 .   ? 19.40000 7.82600  20.04700  0.540 26.69531 ? 304 MER A S14  1 
HETATM 4478 C C15  B MER E 4 .   ? 20.83900 8.17300  21.10500  0.540 31.69591 ? 304 MER A C15  1 
HETATM 4479 C C16  B MER E 4 .   ? 21.42800 6.86100  21.60300  0.540 34.49624 ? 304 MER A C16  1 
HETATM 4480 C C17  B MER E 4 .   ? 22.63600 6.59200  20.68200  0.540 36.64387 ? 304 MER A C17  1 
HETATM 4481 C C18  B MER E 4 .   ? 17.11800 8.40400  21.62000  0.540 21.70260 ? 304 MER A C18  1 
HETATM 4482 N N19  B MER E 4 .   ? 22.56500 7.60300  19.61400  0.540 35.47794 ? 304 MER A N19  1 
HETATM 4483 C C20  B MER E 4 .   ? 16.53200 7.04200  21.24700  0.540 21.54469 ? 304 MER A C20  1 
HETATM 4484 C C21  B MER E 4 .   ? 21.91000 8.76000  20.17200  0.540 33.79879 ? 304 MER A C21  1 
HETATM 4485 C C22  B MER E 4 .   ? 22.62200 5.17100  20.11100  0.540 39.59685 ? 304 MER A C22  1 
HETATM 4486 N N23  B MER E 4 .   ? 23.61500 4.80700  19.27900  0.540 40.99702 ? 304 MER A N23  1 
HETATM 4487 O O24  B MER E 4 .   ? 21.73400 4.39700  20.42600  0.540 40.51275 ? 304 MER A O24  1 
HETATM 4488 C C25  B MER E 4 .   ? 23.44200 4.73100  17.83300  0.540 41.34969 ? 304 MER A C25  1 
HETATM 4489 C C26  B MER E 4 .   ? 24.95400 4.46400  19.74900  0.540 41.61025 ? 304 MER A C26  1 
HETATM 4490 H H3   B MER E 4 .   ? 14.48700 8.39400  20.94000  0.540 20.44000 ? 304 MER A H3   1 
HETATM 4491 H H4   B MER E 4 .   ? 16.21200 10.02500 22.67100  0.540 23.80000 ? 304 MER A H4   1 
HETATM 4492 H H7   B MER E 4 .   ? 14.11900 10.08200 23.50500  0.540 21.52000 ? 304 MER A H7   1 
HETATM 4493 H HO8  B MER E 4 .   ? 13.96300 7.47100  23.85900  0.540 21.51000 ? 304 MER A HO8  1 
HETATM 4494 H H9   B MER E 4 .   ? 11.85400 9.81400  22.68800  0.540 23.06000 ? 304 MER A H9   1 
HETATM 4495 H H9A  B MER E 4 .   ? 12.05800 8.40300  23.67700  0.540 23.06000 ? 304 MER A H9A  1 
HETATM 4496 H H9B  B MER E 4 .   ? 12.19500 8.28000  21.95200  0.540 23.06000 ? 304 MER A H9B  1 
HETATM 4497 H HN10 B MER E 4 .   ? 16.11500 11.39700 20.45700  0.540 25.89000 ? 304 MER A HN10 1 
HETATM 4498 H H15  B MER E 4 .   ? 20.59100 8.83200  21.93600  0.540 38.04000 ? 304 MER A H15  1 
HETATM 4499 H H16  B MER E 4 .   ? 20.68600 6.06500  21.56700  0.540 41.40000 ? 304 MER A H16  1 
HETATM 4500 H H16A B MER E 4 .   ? 21.70800 6.93400  22.65300  0.540 41.40000 ? 304 MER A H16A 1 
HETATM 4501 H H17  B MER E 4 .   ? 23.56300 6.69800  21.24200  0.540 43.98000 ? 304 MER A H17  1 
HETATM 4502 H H18  B MER E 4 .   ? 17.57900 8.32000  22.60300  0.540 26.05000 ? 304 MER A H18  1 
HETATM 4503 H HN19 B MER E 4 .   ? 23.48500 7.81200  19.23900  0.540 42.58000 ? 304 MER A HN19 1 
HETATM 4504 H H20  B MER E 4 .   ? 16.08600 7.03600  20.25300  0.540 25.86000 ? 304 MER A H20  1 
HETATM 4505 H H20A B MER E 4 .   ? 15.74800 6.72200  21.93200  0.540 25.86000 ? 304 MER A H20A 1 
HETATM 4506 H H20B B MER E 4 .   ? 17.27900 6.25000  21.25000  0.540 25.86000 ? 304 MER A H20B 1 
HETATM 4507 H H21  B MER E 4 .   ? 22.63700 9.38700  20.68600  0.540 40.56000 ? 304 MER A H21  1 
HETATM 4508 H H21A B MER E 4 .   ? 21.49900 9.37600  19.37300  0.540 40.56000 ? 304 MER A H21A 1 
HETATM 4509 H H25  B MER E 4 .   ? 23.23600 3.71500  17.50000  0.540 49.63000 ? 304 MER A H25  1 
HETATM 4510 H H25A B MER E 4 .   ? 22.61400 5.34900  17.48900  0.540 49.63000 ? 304 MER A H25A 1 
HETATM 4511 H H25B B MER E 4 .   ? 24.32900 5.06500  17.29700  0.540 49.63000 ? 304 MER A H25B 1 
HETATM 4512 H H26  B MER E 4 .   ? 25.33300 3.55100  19.29200  0.540 49.94000 ? 304 MER A H26  1 
HETATM 4513 H H26A B MER E 4 .   ? 25.68300 5.24300  19.52900  0.540 49.94000 ? 304 MER A H26A 1 
HETATM 4514 H H26B B MER E 4 .   ? 24.98800 4.30600  20.82500  0.540 49.94000 ? 304 MER A H26B 1 
HETATM 4515 S S    . SO4 F 2 .   ? 32.53300 14.18700 2.55300   1.000 41.17336 ? 305 SO4 A S    1 
HETATM 4516 O O1   . SO4 F 2 .   ? 31.50900 13.97900 1.53300   1.000 43.98685 ? 305 SO4 A O1   1 
HETATM 4517 O O2   . SO4 F 2 .   ? 33.64200 13.28300 2.27400   1.000 42.14979 ? 305 SO4 A O2   1 
HETATM 4518 O O3   . SO4 F 2 .   ? 32.99600 15.57200 2.46200   1.000 40.52854 ? 305 SO4 A O3   1 
HETATM 4519 O O4   . SO4 F 2 .   ? 31.99900 13.92400 3.88500   1.000 41.34443 ? 305 SO4 A O4   1 
HETATM 4520 O O    . HOH G 5 .   ? 23.51100 30.44600 31.55400  1.000 35.07526 ? 401 HOH A O    1 
HETATM 4521 O O    A HOH G 5 .   ? 11.18500 11.97300 22.46600  0.580 24.48978 ? 402 HOH A O    1 
HETATM 4522 O O    . HOH G 5 .   ? 17.60400 9.76000  16.86400  1.000 30.44049 ? 403 HOH A O    1 
HETATM 4523 O O    . HOH G 5 .   ? 6.33300  -7.41100 12.04100  1.000 38.94414 ? 404 HOH A O    1 
HETATM 4524 O O    . HOH G 5 .   ? 7.65700  22.16800 -3.54200  1.000 38.65990 ? 405 HOH A O    1 
HETATM 4525 O O    . HOH G 5 .   ? 7.39400  26.65900 2.20400   1.000 31.16953 ? 406 HOH A O    1 
HETATM 4526 O O    . HOH G 5 .   ? 12.15000 14.53900 41.78000  1.000 46.39767 ? 407 HOH A O    1 
HETATM 4527 O O    . HOH G 5 .   ? 28.04400 9.31600  35.68800  1.000 46.17396 ? 408 HOH A O    1 
HETATM 4528 O O    . HOH G 5 .   ? 11.17800 39.89400 22.86500  1.000 41.94977 ? 409 HOH A O    1 
HETATM 4529 O O    . HOH G 5 .   ? 8.69400  -5.82100 10.98800  1.000 41.51024 ? 410 HOH A O    1 
HETATM 4530 O O    . HOH G 5 .   ? 21.47800 10.15700 -4.64600  1.000 34.73838 ? 411 HOH A O    1 
HETATM 4531 O O    . HOH G 5 .   ? 19.60600 2.93300  16.40600  1.000 55.57508 ? 412 HOH A O    1 
HETATM 4532 O O    . HOH G 5 .   ? 9.58000  29.51200 6.74200   1.000 21.19728 ? 413 HOH A O    1 
HETATM 4533 O O    . HOH G 5 .   ? 11.08300 33.36900 7.91800   1.000 33.61719 ? 414 HOH A O    1 
HETATM 4534 O O    . HOH G 5 .   ? 25.41700 15.85900 -1.09100  1.000 31.41956 ? 415 HOH A O    1 
HETATM 4535 O O    . HOH G 5 .   ? 9.81400  32.37000 6.55100   1.000 48.41107 ? 416 HOH A O    1 
HETATM 4536 O O    . HOH G 5 .   ? 9.58700  -1.03800 -5.51800  1.000 42.83145 ? 417 HOH A O    1 
HETATM 4537 O O    . HOH G 5 .   ? 17.07800 27.47000 -6.91000  1.000 34.08830 ? 418 HOH A O    1 
HETATM 4538 O O    . HOH G 5 .   ? 6.43500  -8.66200 15.42400  1.000 40.08902 ? 419 HOH A O    1 
HETATM 4539 O O    . HOH G 5 .   ? 20.56700 7.62200  34.43000  1.000 44.61061 ? 420 HOH A O    1 
HETATM 4540 O O    . HOH G 5 .   ? 0.12800  -0.27200 9.71800   0.480 9.43271  ? 421 HOH A O    1 
HETATM 4541 O O    . HOH G 5 .   ? 18.84600 34.51300 25.73500  1.000 30.15098 ? 422 HOH A O    1 
HETATM 4542 O O    . HOH G 5 .   ? 25.20700 28.96600 2.96900   1.000 24.06604 ? 423 HOH A O    1 
HETATM 4543 O O    . HOH G 5 .   ? 1.72600  -1.47600 21.29700  1.000 30.10887 ? 424 HOH A O    1 
HETATM 4544 O O    . HOH G 5 .   ? 6.25000  21.76100 12.82100  1.000 13.19895 ? 425 HOH A O    1 
HETATM 4545 O O    . HOH G 5 .   ? 31.74300 26.07900 5.65000   1.000 31.93804 ? 426 HOH A O    1 
HETATM 4546 O O    . HOH G 5 .   ? 13.51400 5.85400  23.52900  1.000 32.42231 ? 427 HOH A O    1 
HETATM 4547 O O    . HOH G 5 .   ? 24.16600 17.22800 -4.09100  1.000 50.85083 ? 428 HOH A O    1 
HETATM 4548 O O    A HOH G 5 .   ? 3.32500  11.58900 28.56300  0.500 25.18986 ? 429 HOH A O    1 
HETATM 4549 O O    . HOH G 5 .   ? 12.61600 -4.36400 15.39400  1.000 37.66504 ? 430 HOH A O    1 
HETATM 4550 O O    . HOH G 5 .   ? 23.49600 9.91500  38.35100  1.000 27.37433 ? 431 HOH A O    1 
HETATM 4551 O O    . HOH G 5 .   ? 17.33000 38.24000 27.55100  1.000 39.11785 ? 432 HOH A O    1 
HETATM 4552 O O    . HOH G 5 .   ? 4.24200  -4.74400 21.41000  1.000 36.05959 ? 433 HOH A O    1 
HETATM 4553 O O    . HOH G 5 .   ? 10.23900 28.90900 32.76600  1.000 47.21882 ? 434 HOH A O    1 
HETATM 4554 O O    . HOH G 5 .   ? 1.03400  7.56700  18.76600  1.000 16.01771 ? 435 HOH A O    1 
HETATM 4555 O O    . HOH G 5 .   ? 22.20500 33.44100 13.62700  1.000 29.01664 ? 436 HOH A O    1 
HETATM 4556 O O    . HOH G 5 .   ? 1.44400  8.60500  14.78100  1.000 14.49647 ? 437 HOH A O    1 
HETATM 4557 O O    . HOH G 5 .   ? 7.46200  -2.59500 6.24400   1.000 30.51418 ? 438 HOH A O    1 
HETATM 4558 O O    . HOH G 5 .   ? 5.97000  4.56700  -2.98200  1.000 32.05384 ? 439 HOH A O    1 
HETATM 4559 O O    . HOH G 5 .   ? 17.56200 25.50700 -5.54300  1.000 25.50043 ? 440 HOH A O    1 
HETATM 4560 O O    . HOH G 5 .   ? 27.69200 25.96200 -3.16100  1.000 49.44014 ? 441 HOH A O    1 
HETATM 4561 O O    . HOH G 5 .   ? 1.94500  9.70800  17.26200  1.000 17.24944 ? 442 HOH A O    1 
HETATM 4562 O O    . HOH G 5 .   ? 28.10100 24.87600 18.08600  1.000 30.31153 ? 443 HOH A O    1 
HETATM 4563 O O    . HOH G 5 .   ? 13.37500 8.23900  28.99300  1.000 72.21392 ? 444 HOH A O    1 
HETATM 4564 O O    . HOH G 5 .   ? 2.19400  7.51900  3.87700   1.000 19.63920 ? 445 HOH A O    1 
HETATM 4565 O O    . HOH G 5 .   ? 21.08000 32.86800 11.43400  1.000 27.31906 ? 446 HOH A O    1 
HETATM 4566 O O    . HOH G 5 .   ? 1.17800  -4.15900 7.95800   1.000 25.39778 ? 447 HOH A O    1 
HETATM 4567 O O    . HOH G 5 .   ? 12.95800 19.21400 39.36200  1.000 36.01484 ? 448 HOH A O    1 
HETATM 4568 O O    . HOH G 5 .   ? 4.50000  5.71200  12.87700  1.000 15.29920 ? 449 HOH A O    1 
HETATM 4569 O O    . HOH G 5 .   ? 29.34400 26.77700 5.54000   1.000 25.83731 ? 450 HOH A O    1 
HETATM 4570 O O    . HOH G 5 .   ? 23.58800 6.33600  15.08100  1.000 32.61444 ? 451 HOH A O    1 
HETATM 4571 O O    . HOH G 5 .   ? 28.10900 29.11300 20.89300  1.000 41.27600 ? 452 HOH A O    1 
HETATM 4572 O O    . HOH G 5 .   ? 4.33600  9.20900  18.46400  1.000 21.72103 ? 453 HOH A O    1 
HETATM 4573 O O    . HOH G 5 .   ? 22.37900 15.15700 10.57300  1.000 13.32265 ? 454 HOH A O    1 
HETATM 4574 O O    . HOH G 5 .   ? 6.74100  1.65000  0.82600   1.000 28.17443 ? 455 HOH A O    1 
HETATM 4575 O O    . HOH G 5 .   ? 1.69400  21.12400 7.19200   1.000 21.54469 ? 456 HOH A O    1 
HETATM 4576 O O    . HOH G 5 .   ? 29.97700 14.57100 5.68200   1.000 41.43128 ? 457 HOH A O    1 
HETATM 4577 O O    . HOH G 5 .   ? 28.41300 29.10100 14.88400  1.000 29.78778 ? 458 HOH A O    1 
HETATM 4578 O O    . HOH G 5 .   ? 25.30900 32.17700 -4.72100  1.000 39.02310 ? 459 HOH A O    1 
HETATM 4579 O O    . HOH G 5 .   ? 11.54500 0.14600  20.90900  1.000 35.83851 ? 460 HOH A O    1 
HETATM 4580 O O    . HOH G 5 .   ? 19.84900 18.06500 40.53500  1.000 26.43212 ? 461 HOH A O    1 
HETATM 4581 O O    . HOH G 5 .   ? 20.01900 15.18500 19.40400  1.000 21.37098 ? 462 HOH A O    1 
HETATM 4582 O O    . HOH G 5 .   ? 23.07800 9.73200  13.22400  1.000 16.03877 ? 463 HOH A O    1 
HETATM 4583 O O    . HOH G 5 .   ? 11.79100 13.05500 33.59700  1.000 33.10923 ? 464 HOH A O    1 
HETATM 4584 O O    . HOH G 5 .   ? 24.44600 28.22200 31.88700  1.000 22.66061 ? 465 HOH A O    1 
HETATM 4585 O O    . HOH G 5 .   ? 21.31300 28.20600 -1.95700  1.000 19.62604 ? 466 HOH A O    1 
HETATM 4586 O O    . HOH G 5 .   ? 2.55300  25.10900 5.37100   1.000 22.08159 ? 467 HOH A O    1 
HETATM 4587 O O    . HOH G 5 .   ? 23.96600 6.71700  7.09000   1.000 20.63932 ? 468 HOH A O    1 
HETATM 4588 O O    . HOH G 5 .   ? 29.58800 19.08900 6.99400   1.000 27.04798 ? 469 HOH A O    1 
HETATM 4589 O O    . HOH G 5 .   ? 17.93700 39.49200 22.47200  1.000 35.08842 ? 470 HOH A O    1 
HETATM 4590 O O    . HOH G 5 .   ? 4.57500  20.80100 -1.51100  1.000 19.26284 ? 471 HOH A O    1 
HETATM 4591 O O    . HOH G 5 .   ? 3.90100  27.96800 3.09000   1.000 38.13089 ? 472 HOH A O    1 
HETATM 4592 O O    . HOH G 5 .   ? 19.27400 34.95500 8.15000   1.000 35.91746 ? 473 HOH A O    1 
HETATM 4593 O O    . HOH G 5 .   ? 4.13000  26.20300 8.72000   1.000 18.01269 ? 474 HOH A O    1 
HETATM 4594 O O    . HOH G 5 .   ? 22.64600 23.87800 40.28300  1.000 23.85812 ? 475 HOH A O    1 
HETATM 4595 O O    . HOH G 5 .   ? 25.52900 31.62200 20.58100  1.000 30.98003 ? 476 HOH A O    1 
HETATM 4596 O O    . HOH G 5 .   ? 1.38400  -0.06800 18.80000  1.000 24.06604 ? 477 HOH A O    1 
HETATM 4597 O O    . HOH G 5 .   ? 3.42600  4.06300  10.89200  1.000 19.11808 ? 478 HOH A O    1 
HETATM 4598 O O    A HOH G 5 .   ? 7.55400  7.40200  30.06200  0.700 34.12514 ? 479 HOH A O    1 
HETATM 4599 O O    . HOH G 5 .   ? 28.68800 12.72000 9.02200   1.000 29.92990 ? 480 HOH A O    1 
HETATM 4600 O O    . HOH G 5 .   ? 23.96800 4.16700  10.98000  1.000 41.79975 ? 481 HOH A O    1 
HETATM 4601 O O    . HOH G 5 .   ? 5.88300  27.53900 10.42600  1.000 15.63609 ? 482 HOH A O    1 
HETATM 4602 O O    . HOH G 5 .   ? 3.39300  2.00300  19.91500  1.000 24.70559 ? 483 HOH A O    1 
HETATM 4603 O O    . HOH G 5 .   ? 13.75300 32.40900 -7.45000  1.000 55.90934 ? 484 HOH A O    1 
HETATM 4604 O O    . HOH G 5 .   ? 4.62700  8.33700  -4.40400  1.000 45.59757 ? 485 HOH A O    1 
HETATM 4605 O O    . HOH G 5 .   ? 23.99200 17.95100 -6.78000  1.000 53.33797 ? 486 HOH A O    1 
HETATM 4606 O O    . HOH G 5 .   ? 20.13500 9.65000  15.92600  1.000 23.95814 ? 487 HOH A O    1 
HETATM 4607 O O    . HOH G 5 .   ? 25.56700 14.93900 14.87400  1.000 16.88360 ? 488 HOH A O    1 
HETATM 4608 O O    . HOH G 5 .   ? 28.89700 11.98900 18.04300  1.000 40.55223 ? 489 HOH A O    1 
HETATM 4609 O O    . HOH G 5 .   ? 28.60100 20.92800 13.04900  1.000 26.04260 ? 490 HOH A O    1 
HETATM 4610 O O    . HOH G 5 .   ? 20.57100 25.48900 -7.42100  1.000 29.84042 ? 491 HOH A O    1 
HETATM 4611 O O    . HOH G 5 .   ? 12.41000 3.90600  15.25700  1.000 20.99989 ? 492 HOH A O    1 
HETATM 4612 O O    . HOH G 5 .   ? 28.94100 19.24200 20.69700  1.000 31.64064 ? 493 HOH A O    1 
HETATM 4613 O O    . HOH G 5 .   ? 2.62500  5.97100  24.67400  1.000 34.38833 ? 494 HOH A O    1 
HETATM 4614 O O    . HOH G 5 .   ? 28.42800 18.42300 15.86600  1.000 29.60355 ? 495 HOH A O    1 
HETATM 4615 O O    . HOH G 5 .   ? 23.76100 4.22300  8.23800   1.000 28.94294 ? 496 HOH A O    1 
HETATM 4616 O O    . HOH G 5 .   ? 25.83800 10.85600 15.48000  1.000 17.60211 ? 497 HOH A O    1 
HETATM 4617 O O    . HOH G 5 .   ? 26.69800 7.35700  7.90400   1.000 26.63477 ? 498 HOH A O    1 
HETATM 4618 O O    . HOH G 5 .   ? 14.35400 5.84900  9.28900   1.000 15.68609 ? 499 HOH A O    1 
HETATM 4619 O O    . HOH G 5 .   ? 22.89500 32.25400 25.19000  1.000 34.95682 ? 500 HOH A O    1 
HETATM 4620 O O    . HOH G 5 .   ? 22.60300 6.41900  2.60800   1.000 20.56036 ? 501 HOH A O    1 
HETATM 4621 O O    . HOH G 5 .   ? 25.77800 11.25600 21.50600  1.000 33.58034 ? 502 HOH A O    1 
HETATM 4622 O O    . HOH G 5 .   ? 6.22000  11.83000 18.44300  1.000 14.53595 ? 503 HOH A O    1 
HETATM 4623 O O    . HOH G 5 .   ? 21.65100 35.84300 14.67100  1.000 29.42458 ? 504 HOH A O    1 
HETATM 4624 O O    . HOH G 5 .   ? 0.06800  30.59500 9.85200   1.000 36.06222 ? 505 HOH A O    1 
HETATM 4625 O O    . HOH G 5 .   ? 4.08700  29.01400 25.22400  1.000 29.70093 ? 506 HOH A O    1 
HETATM 4626 O O    . HOH G 5 .   ? 18.71100 32.68400 4.11300   1.000 30.26152 ? 507 HOH A O    1 
HETATM 4627 O O    . HOH G 5 .   ? 11.00400 -1.23700 15.54400  1.000 41.43655 ? 508 HOH A O    1 
HETATM 4628 O O    . HOH G 5 .   ? 17.68200 0.56600  12.80500  1.000 33.91459 ? 509 HOH A O    1 
HETATM 4629 O O    . HOH G 5 .   ? 23.19800 15.39300 -3.10000  1.000 28.65080 ? 510 HOH A O    1 
HETATM 4630 O O    . HOH G 5 .   ? -4.96200 5.71700  14.47900  1.000 17.96268 ? 511 HOH A O    1 
HETATM 4631 O O    . HOH G 5 .   ? -0.74300 29.88200 14.33100  1.000 23.75285 ? 512 HOH A O    1 
HETATM 4632 O O    . HOH G 5 .   ? 0.12600  30.88400 20.76300  1.000 25.22408 ? 513 HOH A O    1 
HETATM 4633 O O    . HOH G 5 .   ? 26.15300 16.49700 -5.79300  1.000 38.52041 ? 514 HOH A O    1 
HETATM 4634 O O    . HOH G 5 .   ? 14.03000 -1.31300 5.74400   1.000 42.96305 ? 515 HOH A O    1 
HETATM 4635 O O    . HOH G 5 .   ? 28.47600 31.93000 17.46100  1.000 34.52519 ? 516 HOH A O    1 
HETATM 4636 O O    . HOH G 5 .   ? 21.14000 7.70200  30.40300  1.000 31.81171 ? 517 HOH A O    1 
HETATM 4637 O O    . HOH G 5 .   ? -0.41900 7.46700  25.51300  1.000 35.61743 ? 518 HOH A O    1 
HETATM 4638 O O    . HOH G 5 .   ? 7.66300  -1.51400 0.02800   1.000 44.45270 ? 519 HOH A O    1 
HETATM 4639 O O    . HOH G 5 .   ? 8.25200  35.05000 17.23900  1.000 32.80657 ? 520 HOH A O    1 
HETATM 4640 O O    . HOH G 5 .   ? 12.94900 39.17700 16.20200  1.000 38.93888 ? 521 HOH A O    1 
HETATM 4641 O O    . HOH G 5 .   ? 14.04100 4.99500  20.48400  1.000 31.29586 ? 522 HOH A O    1 
HETATM 4642 O O    . HOH G 5 .   ? 4.24600  3.46900  5.66700   1.000 24.58453 ? 523 HOH A O    1 
HETATM 4643 O O    . HOH G 5 .   ? 24.63800 9.53200  19.45300  1.000 47.93469 ? 524 HOH A O    1 
HETATM 4644 O O    . HOH G 5 .   ? 25.65300 22.67700 42.27200  1.000 18.84700 ? 525 HOH A O    1 
HETATM 4645 O O    . HOH G 5 .   ? 24.55200 20.47100 28.39300  1.000 25.85573 ? 526 HOH A O    1 
HETATM 4646 O O    . HOH G 5 .   ? 24.32800 34.12000 20.59200  1.000 32.41968 ? 527 HOH A O    1 
HETATM 4647 O O    . HOH G 5 .   ? 31.95800 23.87900 -0.98400  1.000 15.32026 ? 528 HOH A O    1 
HETATM 4648 O O    . HOH G 5 .   ? 8.26800  30.55800 24.59900  1.000 27.80333 ? 529 HOH A O    1 
HETATM 4649 O O    . HOH G 5 .   ? 28.09200 16.92400 7.75900   1.000 25.55833 ? 530 HOH A O    1 
HETATM 4650 O O    . HOH G 5 .   ? 19.23300 15.04000 43.38400  1.000 32.82499 ? 531 HOH A O    1 
HETATM 4651 O O    . HOH G 5 .   ? 14.94900 33.78300 14.33000  1.000 18.75225 ? 532 HOH A O    1 
HETATM 4652 O O    . HOH G 5 .   ? 29.12800 24.91600 -1.94700  1.000 24.04236 ? 533 HOH A O    1 
HETATM 4653 O O    . HOH G 5 .   ? 19.53600 33.22400 36.89300  1.000 30.79317 ? 534 HOH A O    1 
HETATM 4654 O O    . HOH G 5 .   ? 20.27900 34.12800 32.20700  1.000 30.12466 ? 535 HOH A O    1 
HETATM 4655 O O    . HOH G 5 .   ? 12.56900 -3.75800 9.64200   1.000 32.32756 ? 536 HOH A O    1 
HETATM 4656 O O    . HOH G 5 .   ? 1.76700  25.07700 9.61000   1.000 17.77318 ? 537 HOH A O    1 
HETATM 4657 O O    . HOH G 5 .   ? 6.68300  34.22000 19.11900  1.000 34.30674 ? 538 HOH A O    1 
HETATM 4658 O O    . HOH G 5 .   ? 16.37400 6.01100  -4.99900  1.000 29.16402 ? 539 HOH A O    1 
HETATM 4659 O O    . HOH G 5 .   ? 19.76000 5.10900  14.69700  1.000 20.23927 ? 540 HOH A O    1 
HETATM 4660 O O    . HOH G 5 .   ? 16.06800 32.82700 5.09800   1.000 31.34060 ? 541 HOH A O    1 
HETATM 4661 O O    . HOH G 5 .   ? 28.88900 10.20800 4.39400   1.000 41.08651 ? 542 HOH A O    1 
HETATM 4662 O O    . HOH G 5 .   ? 17.71600 24.60300 46.04700  1.000 39.01520 ? 543 HOH A O    1 
HETATM 4663 O O    . HOH G 5 .   ? 26.91800 18.25800 44.94800  1.000 30.60630 ? 544 HOH A O    1 
HETATM 4664 O O    . HOH G 5 .   ? -1.06000 12.63700 7.32000   1.000 22.71851 ? 545 HOH A O    1 
HETATM 4665 O O    . HOH G 5 .   ? 11.26300 -0.51100 7.90100   1.000 28.57711 ? 546 HOH A O    1 
HETATM 4666 O O    . HOH G 5 .   ? 25.28400 26.36800 25.66200  1.000 34.80417 ? 547 HOH A O    1 
HETATM 4667 O O    . HOH G 5 .   ? -2.43400 13.99400 26.25600  1.000 37.23078 ? 548 HOH A O    1 
HETATM 4668 O O    . HOH G 5 .   ? 10.67500 34.92700 9.99100   1.000 30.30627 ? 549 HOH A O    1 
HETATM 4669 O O    . HOH G 5 .   ? 3.01200  36.01400 17.57100  1.000 44.87380 ? 550 HOH A O    1 
HETATM 4670 O O    . HOH G 5 .   ? 9.28600  26.08600 -4.98700  1.000 51.28246 ? 551 HOH A O    1 
HETATM 4671 O O    . HOH G 5 .   ? 11.81500 1.24800  14.88300  1.000 26.00049 ? 552 HOH A O    1 
HETATM 4672 O O    . HOH G 5 .   ? 0.17600  9.95900  9.64800   1.000 29.61934 ? 553 HOH A O    1 
HETATM 4673 O O    . HOH G 5 .   ? 0.36300  20.85500 28.42700  1.000 31.74591 ? 554 HOH A O    1 
HETATM 4674 O O    . HOH G 5 .   ? -6.79000 14.73100 18.35400  1.000 22.08159 ? 555 HOH A O    1 
HETATM 4675 O O    . HOH G 5 .   ? 0.56500  7.53700  10.59900  1.000 19.97871 ? 556 HOH A O    1 
HETATM 4676 O O    . HOH G 5 .   ? 20.14600 9.05600  -2.57800  1.000 22.93959 ? 557 HOH A O    1 
HETATM 4677 O O    . HOH G 5 .   ? -5.49300 11.28700 15.37200  1.000 18.75225 ? 558 HOH A O    1 
HETATM 4678 O O    . HOH G 5 .   ? 25.72600 8.29000  35.58000  1.000 61.71003 ? 559 HOH A O    1 
HETATM 4679 O O    . HOH G 5 .   ? 2.64900  28.39300 8.12500   1.000 36.91758 ? 560 HOH A O    1 
HETATM 4680 O O    . HOH G 5 .   ? 25.92200 24.20500 -5.63200  1.000 30.46155 ? 561 HOH A O    1 
HETATM 4681 O O    . HOH G 5 .   ? 26.62800 27.36200 22.29000  1.000 32.27492 ? 562 HOH A O    1 
HETATM 4682 O O    . HOH G 5 .   ? -3.12000 11.71000 25.11800  1.000 33.27767 ? 563 HOH A O    1 
HETATM 4683 O O    . HOH G 5 .   ? 28.68100 17.19000 10.34900  1.000 26.90059 ? 564 HOH A O    1 
HETATM 4684 O O    . HOH G 5 .   ? 35.83200 20.55900 7.43100   1.000 40.21798 ? 565 HOH A O    1 
HETATM 4685 O O    . HOH G 5 .   ? 7.02400  9.48800  -7.16700  1.000 43.06043 ? 566 HOH A O    1 
HETATM 4686 O O    . HOH G 5 .   ? 6.44300  14.62800 -4.99000  1.000 31.07215 ? 567 HOH A O    1 
HETATM 4687 O O    . HOH G 5 .   ? 12.81400 16.13500 40.14800  1.000 35.18053 ? 568 HOH A O    1 
HETATM 4688 O O    . HOH G 5 .   ? 19.55000 2.11600  13.20900  1.000 59.49661 ? 569 HOH A O    1 
HETATM 4689 O O    . HOH G 5 .   ? 17.85000 34.30100 29.95500  1.000 24.82929 ? 570 HOH A O    1 
HETATM 4690 O O    . HOH G 5 .   ? 28.70500 22.64700 11.26000  1.000 32.84341 ? 571 HOH A O    1 
HETATM 4691 O O    . HOH G 5 .   ? 3.61200  32.31800 9.15200   1.000 43.27098 ? 572 HOH A O    1 
HETATM 4692 O O    . HOH G 5 .   ? 9.22300  10.42900 11.87200  1.000 12.23041 ? 573 HOH A O    1 
HETATM 4693 O O    . HOH G 5 .   ? 22.43900 7.83100  -1.51600  1.000 28.11127 ? 574 HOH A O    1 
HETATM 4694 O O    . HOH G 5 .   ? 27.46300 23.80500 -3.95300  1.000 37.38343 ? 575 HOH A O    1 
HETATM 4695 O O    . HOH G 5 .   ? 16.20100 11.71900 44.49900  1.000 27.42434 ? 576 HOH A O    1 
HETATM 4696 O O    . HOH G 5 .   ? 12.82300 14.93100 33.85400  1.000 36.45174 ? 577 HOH A O    1 
HETATM 4697 O O    C HOH G 5 .   ? 5.44900  10.53700 29.26800  0.700 44.06844 ? 578 HOH A O    1 
HETATM 4698 O O    . HOH G 5 .   ? 10.65200 -2.10500 17.57200  1.000 35.41477 ? 579 HOH A O    1 
HETATM 4699 O O    . HOH G 5 .   ? 18.95900 7.62000  32.94200  1.000 43.21571 ? 580 HOH A O    1 
HETATM 4700 O O    . HOH G 5 .   ? 15.64700 32.71400 38.41000  1.000 47.36094 ? 581 HOH A O    1 
HETATM 4701 O O    . HOH G 5 .   ? 17.09600 40.99500 16.71100  1.000 34.84365 ? 582 HOH A O    1 
HETATM 4702 O O    . HOH G 5 .   ? 22.83900 32.41700 7.27800   1.000 29.40616 ? 583 HOH A O    1 
HETATM 4703 O O    . HOH G 5 .   ? 20.91300 19.31100 43.11400  1.000 37.86770 ? 584 HOH A O    1 
HETATM 4704 O O    . HOH G 5 .   ? -0.80600 11.00100 11.91200  1.000 29.90885 ? 585 HOH A O    1 
HETATM 4705 O O    . HOH G 5 .   ? 5.61900  23.46700 -2.05200  1.000 31.94857 ? 586 HOH A O    1 
HETATM 4706 O O    . HOH G 5 .   ? 22.05200 31.28900 -3.28100  1.000 32.89605 ? 587 HOH A O    1 
HETATM 4707 O O    . HOH G 5 .   ? 19.97700 5.30700  30.15600  1.000 42.14189 ? 588 HOH A O    1 
HETATM 4708 O O    . HOH G 5 .   ? 19.55300 30.04900 -4.38600  1.000 33.88038 ? 589 HOH A O    1 
HETATM 4709 O O    . HOH G 5 .   ? 4.43800  4.29500  1.45000   1.000 39.48105 ? 590 HOH A O    1 
HETATM 4710 O O    . HOH G 5 .   ? -0.52400 9.91900  5.84600   1.000 28.22707 ? 591 HOH A O    1 
HETATM 4711 O O    . HOH G 5 .   ? -3.68800 5.95400  19.14600  1.000 31.89856 ? 592 HOH A O    1 
HETATM 4712 O O    . HOH G 5 .   ? 6.47300  5.02500  23.49200  1.000 40.41274 ? 593 HOH A O    1 
HETATM 4713 O O    . HOH G 5 .   ? 13.04000 35.05700 6.43900   1.000 37.77295 ? 594 HOH A O    1 
HETATM 4714 O O    . HOH G 5 .   ? 25.46600 13.32000 39.68600  1.000 23.12383 ? 595 HOH A O    1 
HETATM 4715 O O    . HOH G 5 .   ? 4.20400  -4.63700 5.69800   1.000 35.69375 ? 596 HOH A O    1 
HETATM 4716 O O    . HOH G 5 .   ? 26.62900 10.25800 37.62900  1.000 35.60164 ? 597 HOH A O    1 
HETATM 4717 O O    . HOH G 5 .   ? -1.86300 5.49300  23.21300  1.000 31.82224 ? 598 HOH A O    1 
HETATM 4718 O O    . HOH G 5 .   ? 13.87500 10.68000 43.45500  1.000 30.95371 ? 599 HOH A O    1 
HETATM 4719 O O    . HOH G 5 .   ? 25.09500 19.62200 25.86400  1.000 31.29849 ? 600 HOH A O    1 
HETATM 4720 O O    . HOH G 5 .   ? 26.92300 24.68000 22.05500  1.000 38.73886 ? 601 HOH A O    1 
HETATM 4721 O O    . HOH G 5 .   ? 24.60000 28.53000 26.45400  1.000 47.62150 ? 602 HOH A O    1 
HETATM 4722 O O    . HOH G 5 .   ? 7.81700  3.85000  21.72500  1.000 43.02358 ? 603 HOH A O    1 
HETATM 4723 O O    . HOH G 5 .   ? 30.73000 26.53100 11.22000  1.000 39.04679 ? 604 HOH A O    1 
HETATM 4724 O O    . HOH G 5 .   ? 21.43100 7.34700  16.10500  1.000 44.07371 ? 605 HOH A O    1 
HETATM 4725 O O    . HOH G 5 .   ? 28.90200 19.03700 23.16600  1.000 52.83265 ? 606 HOH A O    1 
HETATM 4726 O O    . HOH G 5 .   ? -3.89900 6.62300  24.49000  1.000 43.57628 ? 607 HOH A O    1 
HETATM 4727 O O    . HOH G 5 .   ? 27.04800 23.11100 24.95800  1.000 40.53644 ? 608 HOH A O    1 
HETATM 4728 O O    . HOH G 5 .   ? 12.61300 30.22100 1.18900   1.000 60.65727 ? 609 HOH A O    1 
HETATM 4729 O O    . HOH G 5 .   ? 11.80800 38.63100 18.47500  1.000 44.17372 ? 610 HOH A O    1 
HETATM 4730 O O    . HOH G 5 .   ? 34.72100 25.71600 2.82400   1.000 27.25064 ? 611 HOH A O    1 
HETATM 4731 O O    . HOH G 5 .   ? 24.65800 6.81400  4.38000   1.000 29.07191 ? 612 HOH A O    1 
HETATM 4732 O O    A HOH G 5 .   ? 21.15600 3.51400  14.81500  0.830 43.44205 ? 613 HOH A O    1 
HETATM 4733 O O    . HOH G 5 .   ? 1.22000  5.41400  8.77000   1.000 40.78121 ? 614 HOH A O    1 
HETATM 4734 O O    . HOH G 5 .   ? 15.31800 23.53400 -7.60000  1.000 41.17599 ? 615 HOH A O    1 
HETATM 4735 O O    . HOH G 5 .   ? -5.84000 9.75900  19.13700  1.000 39.06258 ? 616 HOH A O    1 
HETATM 4736 O O    . HOH G 5 .   ? 10.10300 12.15900 35.35400  1.000 55.23294 ? 617 HOH A O    1 
HETATM 4737 O O    . HOH G 5 .   ? 10.19600 2.23300  22.10700  1.000 44.38690 ? 618 HOH A O    1 
HETATM 4738 O O    . HOH G 5 .   ? 16.96400 3.46800  -3.88400  1.000 41.62604 ? 619 HOH A O    1 
HETATM 4739 O O    . HOH G 5 .   ? 27.71600 16.07500 -9.50200  1.000 46.10816 ? 620 HOH A O    1 
HETATM 4740 O O    . HOH G 5 .   ? 24.28700 8.28800  16.39300  1.000 43.50258 ? 621 HOH A O    1 
HETATM 4741 O O    . HOH G 5 .   ? 0.40700  4.68200  23.31100  1.000 34.46992 ? 622 HOH A O    1 
HETATM 4742 O O    . HOH G 5 .   ? 27.15800 30.51700 4.16800   1.000 52.46155 ? 623 HOH A O    1 
HETATM 4743 O O    . HOH G 5 .   ? 24.98300 25.48900 27.92300  1.000 40.08112 ? 624 HOH A O    1 
HETATM 4744 O O    . HOH G 5 .   ? 3.68800  9.79400  -3.09500  1.000 44.72115 ? 625 HOH A O    1 
HETATM 4745 O O    A HOH G 5 .   ? 1.24400  11.80000 28.57800  0.780 32.78025 ? 626 HOH A O    1 
HETATM 4746 O O    . HOH G 5 .   ? 0.52500  25.23900 7.23900   1.000 25.72677 ? 627 HOH A O    1 
HETATM 4747 O O    . HOH G 5 .   ? 1.17000  5.61800  2.09600   1.000 42.29191 ? 628 HOH A O    1 
HETATM 4748 O O    . HOH G 5 .   ? 3.98200  31.11500 23.30200  1.000 39.11258 ? 629 HOH A O    1 
HETATM 4749 O O    . HOH G 5 .   ? 18.25400 41.83600 18.37000  1.000 61.79951 ? 630 HOH A O    1 
HETATM 4750 O O    . HOH G 5 .   ? -1.35500 23.23300 6.81600   1.000 36.72809 ? 631 HOH A O    1 
HETATM 4751 O O    . HOH G 5 .   ? 2.74100  4.02000  8.07500   1.000 29.03769 ? 632 HOH A O    1 
HETATM 4752 O O    B HOH G 5 .   ? 18.11900 3.09100  17.53900  0.610 34.68311 ? 633 HOH A O    1 
HETATM 4753 O O    . HOH G 5 .   ? -0.48800 32.59700 18.52400  1.000 42.36824 ? 634 HOH A O    1 
HETATM 4754 O O    . HOH G 5 .   ? 4.32800  -0.02000 3.15900   1.000 47.58465 ? 635 HOH A O    1 
HETATM 4755 O O    . HOH G 5 .   ? 2.57600  7.79400  12.32600  1.000 22.79747 ? 636 HOH A O    1 
HETATM 4756 O O    . HOH G 5 .   ? 3.51000  5.34800  -3.97600  1.000 50.43499 ? 637 HOH A O    1 
HETATM 4757 O O    . HOH G 5 .   ? -5.05500 14.83800 11.89400  1.000 37.57819 ? 638 HOH A O    1 
HETATM 4758 O O    . HOH G 5 .   ? 20.73900 33.65600 24.09900  1.000 30.86686 ? 639 HOH A O    1 
HETATM 4759 O O    . HOH G 5 .   ? 29.73100 12.26000 6.79800   1.000 39.00468 ? 640 HOH A O    1 
HETATM 4760 O O    . HOH G 5 .   ? 4.59500  35.85200 19.52800  1.000 53.42746 ? 641 HOH A O    1 
HETATM 4761 O O    . HOH G 5 .   ? -5.65900 12.36900 17.93600  1.000 26.71373 ? 642 HOH A O    1 
HETATM 4762 O O    . HOH G 5 .   ? 14.31400 -1.84000 -9.47100  1.000 43.91316 ? 643 HOH A O    1 
HETATM 4763 O O    . HOH G 5 .   ? 19.76700 35.37100 28.22800  1.000 35.93062 ? 644 HOH A O    1 
HETATM 4764 O O    . HOH G 5 .   ? 23.30500 8.08700  37.36800  1.000 56.37781 ? 645 HOH A O    1 
HETATM 4765 O O    . HOH G 5 .   ? 1.75000  22.51300 4.97000   1.000 24.88456 ? 646 HOH A O    1 
HETATM 4766 O O    . HOH G 5 .   ? 30.66600 28.80600 9.37500   1.000 40.26009 ? 647 HOH A O    1 
HETATM 4767 O O    . HOH G 5 .   ? -1.13200 31.18400 12.04100  1.000 27.85334 ? 648 HOH A O    1 
HETATM 4768 O O    . HOH G 5 .   ? 34.12900 27.58700 4.53300   1.000 46.73718 ? 649 HOH A O    1 
HETATM 4769 O O    . HOH G 5 .   ? 4.50900  2.90800  -0.97600  1.000 43.34730 ? 650 HOH A O    1 
HETATM 4770 O O    . HOH G 5 .   ? 24.95700 10.73700 40.64800  1.000 23.36859 ? 651 HOH A O    1 
HETATM 4771 O O    . HOH G 5 .   ? 4.57500  4.26200  24.51900  1.000 66.17636 ? 652 HOH A O    1 
HETATM 4772 O O    . HOH G 5 .   ? 29.74400 31.43900 15.07500  1.000 51.81937 ? 653 HOH A O    1 
HETATM 4773 O O    . HOH G 5 .   ? 7.26400  32.68400 23.65600  1.000 37.49660 ? 654 HOH A O    1 
HETATM 4774 O O    . HOH G 5 .   ? 22.37600 34.09500 29.33300  1.000 38.84413 ? 655 HOH A O    1 
HETATM 4775 O O    . HOH G 5 .   ? 5.48900  2.04800  21.84200  1.000 34.30411 ? 656 HOH A O    1 
HETATM 4776 O O    . HOH G 5 .   ? -0.55500 -2.17000 8.02400   1.000 19.08387 ? 657 HOH A O    1 
HETATM 4777 O O    . HOH G 5 .   ? -4.40600 13.43000 10.46100  1.000 35.85693 ? 658 HOH A O    1 
HETATM 4778 O O    . HOH G 5 .   ? 3.08500  1.74200  4.07800   1.000 44.00264 ? 659 HOH A O    1 
HETATM 4779 O O    . HOH G 5 .   ? -2.17200 11.37300 4.35100   1.000 36.81231 ? 660 HOH A O    1 
HETATM 4780 O O    . HOH G 5 .   ? 11.21200 15.61400 35.26100  1.000 45.82655 ? 661 HOH A O    1 
HETATM 4781 O O    . HOH G 5 .   ? 31.70800 22.59600 10.53300  1.000 29.69303 ? 662 HOH A O    1 
HETATM 4782 O O    . HOH G 5 .   ? 7.47200  35.30300 14.43300  1.000 37.95981 ? 663 HOH A O    1 
HETATM 4783 O O    . HOH G 5 .   ? 23.47400 30.72800 -5.59700  1.000 38.93888 ? 664 HOH A O    1 
HETATM 4784 O O    . HOH G 5 .   ? 2.12500  -4.04400 5.38700   1.000 35.60953 ? 665 HOH A O    1 
HETATM 4785 O O    . HOH G 5 .   ? -5.35000 6.32900  17.26500  1.000 35.08842 ? 666 HOH A O    1 
HETATM 4786 O O    . HOH G 5 .   ? 6.13000  25.67700 -5.71300  1.000 51.54565 ? 667 HOH A O    1 
HETATM 4787 O O    . HOH G 5 .   ? -2.94500 30.11800 15.95300  1.000 32.43020 ? 668 HOH A O    1 
HETATM 4788 O O    . HOH G 5 .   ? 21.35100 8.00000  38.89600  1.000 47.58992 ? 669 HOH A O    1 
HETATM 4789 O O    . HOH G 5 .   ? 18.18500 14.62100 45.47400  1.000 48.46634 ? 670 HOH A O    1 
HETATM 4790 O O    . HOH G 5 .   ? 31.40200 15.85200 7.93300   1.000 38.76254 ? 671 HOH A O    1 
HETATM 4791 O O    . HOH G 5 .   ? 27.79000 30.94500 6.58100   1.000 48.75058 ? 672 HOH A O    1 
HETATM 4792 O O    . HOH G 5 .   ? 16.29100 4.10200  -7.99300  1.000 83.44948 ? 673 HOH A O    1 
HETATM 4793 O O    . HOH G 5 .   ? 26.22400 22.96200 27.86500  1.000 33.79089 ? 674 HOH A O    1 
HETATM 4794 O O    . HOH G 5 .   ? 11.50100 16.01400 37.78700  1.000 57.95169 ? 675 HOH A O    1 
HETATM 4795 O O    A HOH G 5 .   ? 0.28200  9.55100  28.05000  0.810 32.57496 ? 676 HOH A O    1 
HETATM 4796 O O    . HOH G 5 .   ? -6.98300 13.39600 13.94300  1.000 30.35364 ? 677 HOH A O    1 
HETATM 4797 O O    . HOH G 5 .   ? 18.52000 6.97600  -3.47200  1.000 38.60726 ? 678 HOH A O    1 
HETATM 4798 O O    . HOH G 5 .   ? 28.56200 28.85700 7.59400   1.000 32.40652 ? 679 HOH A O    1 
HETATM 4799 O O    . HOH G 5 .   ? 18.40800 41.54400 20.87400  1.000 39.20733 ? 680 HOH A O    1 
HETATM 4800 O O    . HOH G 5 .   ? 19.73000 6.64800  36.81700  1.000 59.70189 ? 681 HOH A O    1 
HETATM 4801 O O    . HOH G 5 .   ? 7.96200  33.91400 7.58400   1.000 37.88086 ? 682 HOH A O    1 
HETATM 4802 O O    . HOH G 5 .   ? 18.13100 10.95800 46.07300  1.000 42.36297 ? 683 HOH A O    1 
HETATM 4803 O O    . HOH G 5 .   ? 35.20000 15.15900 7.63000   1.000 87.19730 ? 684 HOH A O    1 
HETATM 4804 O O    . HOH G 5 .   ? 20.69800 33.57900 5.90500   1.000 36.42805 ? 685 HOH A O    1 
HETATM 4805 O O    . HOH G 5 .   ? 0.28100  1.27600  5.39600   1.000 32.50653 ? 686 HOH A O    1 
HETATM 4806 O O    D HOH G 5 .   ? 7.94100  14.59800 29.45100  0.680 45.58178 ? 687 HOH A O    1 
HETATM 4807 O O    . HOH G 5 .   ? 24.03400 9.92600  42.99900  1.000 33.69088 ? 688 HOH A O    1 
HETATM 4808 O O    . HOH G 5 .   ? -9.14300 13.99800 13.30900  1.000 39.81793 ? 689 HOH A O    1 
HETATM 4809 O O    . HOH G 5 .   ? 25.84300 8.94000  44.78000  1.000 39.48631 ? 690 HOH A O    1 
HETATM 4810 O O    . HOH G 5 .   ? -1.44200 1.75400  4.09700   1.000 45.79233 ? 691 HOH A O    1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . THR A 23  ? 0.51910 0.53240 0.32170 -0.07450 -0.07180 0.00730  26  THR A N   
2    C CA  . THR A 23  ? 0.51690 0.54530 0.34590 -0.07810 -0.02400 -0.00110 26  THR A CA  
3    C C   . THR A 23  ? 0.51620 0.54620 0.36610 -0.05680 -0.05360 -0.00200 26  THR A C   
4    O O   . THR A 23  ? 0.51520 0.54520 0.35120 -0.05980 -0.08850 0.01390  26  THR A O   
5    C CB  . THR A 23  ? 0.50990 0.54830 0.34460 -0.10620 0.02270  0.00750  26  THR A CB  
6    O OG1 . THR A 23  ? 0.48470 0.54280 0.26360 -0.14690 0.02930  0.02300  26  THR A OG1 
7    C CG2 . THR A 23  ? 0.52120 0.55450 0.36090 -0.09280 0.03590  0.00350  26  THR A CG2 
14   N N   . ASN A 24  ? 0.51400 0.54910 0.37450 -0.03590 -0.03960 -0.00460 27  ASN A N   
15   C CA  . ASN A 24  ? 0.52710 0.55580 0.37940 -0.01740 -0.02460 -0.00530 27  ASN A CA  
16   C C   . ASN A 24  ? 0.48250 0.52270 0.27750 0.00490  -0.02080 -0.01420 27  ASN A C   
17   O O   . ASN A 24  ? 0.46880 0.52510 0.29210 0.01460  -0.01500 -0.03170 27  ASN A O   
18   C CB  . ASN A 24  ? 0.58400 0.59620 0.48600 -0.02470 -0.02620 -0.00640 27  ASN A CB  
19   C CG  . ASN A 24  ? 0.64420 0.63410 0.58110 -0.03350 -0.01380 0.00270  27  ASN A CG  
20   O OD1 . ASN A 24  ? 0.66950 0.64780 0.60760 -0.03420 -0.00720 0.00840  27  ASN A OD1 
21   N ND2 . ASN A 24  ? 0.66250 0.64700 0.61380 -0.03770 -0.01110 0.00660  27  ASN A ND2 
28   N N   . LEU A 25  ? 0.43680 0.48810 0.15300 0.01360  -0.00810 -0.00100 28  LEU A N   
29   C CA  . LEU A 25  ? 0.45130 0.45640 0.18700 0.00600  -0.06450 0.00590  28  LEU A CA  
30   C C   . LEU A 25  ? 0.44020 0.44100 0.21820 0.01890  -0.07790 0.02680  28  LEU A C   
31   O O   . LEU A 25  ? 0.46800 0.43110 0.24250 0.02480  -0.07230 0.02900  28  LEU A O   
32   C CB  . LEU A 25  ? 0.46660 0.44200 0.18990 0.00580  -0.03960 -0.01810 28  LEU A CB  
33   C CG  . LEU A 25  ? 0.45670 0.43150 0.18590 0.00510  -0.03530 -0.03010 28  LEU A CG  
34   C CD1 . LEU A 25  ? 0.44770 0.42840 0.19210 -0.00160 -0.04130 -0.04570 28  LEU A CD1 
35   C CD2 . LEU A 25  ? 0.45110 0.43460 0.18390 0.00920  -0.01580 -0.01720 28  LEU A CD2 
47   N N   . VAL A 26  ? 0.41780 0.43540 0.24200 0.00830  -0.07240 0.02540  29  VAL A N   
48   C CA  . VAL A 26  ? 0.41010 0.42000 0.25550 -0.01180 -0.08930 0.01130  29  VAL A CA  
49   C C   . VAL A 26  ? 0.42670 0.41300 0.28320 -0.00620 -0.08710 0.04410  29  VAL A C   
50   O O   . VAL A 26  ? 0.44470 0.40940 0.26150 0.00510  -0.07550 0.10070  29  VAL A O   
51   C CB  . VAL A 26  ? 0.37930 0.41430 0.26000 -0.02740 -0.10200 -0.00740 29  VAL A CB  
52   C CG1 . VAL A 26  ? 0.35460 0.41520 0.26930 -0.04170 -0.14530 -0.00960 29  VAL A CG1 
53   C CG2 . VAL A 26  ? 0.37770 0.40950 0.24220 -0.03770 -0.11630 0.00600  29  VAL A CG2 
63   N N   . ALA A 27  ? 0.42980 0.40440 0.29300 -0.00380 -0.11400 0.03810  30  ALA A N   
64   C CA  . ALA A 27  ? 0.43620 0.39830 0.29620 -0.00880 -0.07670 0.03070  30  ALA A CA  
65   C C   . ALA A 27  ? 0.43010 0.39930 0.27510 -0.01200 -0.07200 0.02030  30  ALA A C   
66   O O   . ALA A 27  ? 0.42870 0.39870 0.23420 -0.00180 -0.08090 0.02780  30  ALA A O   
67   C CB  . ALA A 27  ? 0.43950 0.39210 0.31590 -0.01520 -0.06780 0.04160  30  ALA A CB  
73   N N   . GLU A 28  ? 0.41610 0.40070 0.28160 -0.01810 -0.06290 0.00520  31  GLU A N   
74   C CA  A GLU A 28  ? 0.40930 0.40210 0.28610 -0.01630 -0.04960 0.00050  31  GLU A CA  
75   C CA  B GLU A 28  ? 0.40850 0.40320 0.28650 -0.02030 -0.05190 0.00170  31  GLU A CA  
76   C C   . GLU A 28  ? 0.37950 0.40070 0.25560 -0.03040 -0.03550 0.00360  31  GLU A C   
77   O O   . GLU A 28  ? 0.36720 0.40520 0.20940 -0.01930 -0.03840 -0.01410 31  GLU A O   
78   C CB  A GLU A 28  ? 0.43130 0.40480 0.32520 -0.00490 -0.03530 -0.00410 31  GLU A CB  
79   C CB  B GLU A 28  ? 0.42770 0.40690 0.32880 -0.01820 -0.03780 0.00070  31  GLU A CB  
80   C CG  A GLU A 28  ? 0.44600 0.40880 0.35830 0.00830  -0.03040 -0.00710 31  GLU A CG  
81   C CG  B GLU A 28  ? 0.43730 0.41110 0.36450 -0.01490 -0.03420 0.00240  31  GLU A CG  
82   C CD  A GLU A 28  ? 0.45770 0.41400 0.39030 0.01740  -0.02520 -0.00720 31  GLU A CD  
83   C CD  B GLU A 28  ? 0.44680 0.41860 0.39730 -0.01400 -0.02880 0.00130  31  GLU A CD  
84   O OE1 A GLU A 28  ? 0.45860 0.41630 0.40400 0.01430  -0.02940 -0.00490 31  GLU A OE1 
85   O OE1 B GLU A 28  ? 0.45890 0.42500 0.41370 -0.01130 -0.01610 -0.00440 31  GLU A OE1 
86   O OE2 A GLU A 28  ? 0.46670 0.41750 0.40140 0.02650  -0.01940 -0.01020 31  GLU A OE2 
87   O OE2 B GLU A 28  ? 0.45310 0.42120 0.40460 -0.01480 -0.03240 0.00760  31  GLU A OE2 
100  N N   . PRO A 29  ? 0.34520 0.39040 0.23970 -0.05900 0.01130  0.01680  32  PRO A N   
101  C CA  . PRO A 29  ? 0.31140 0.37660 0.20560 -0.06520 0.02660  0.00980  32  PRO A CA  
102  C C   . PRO A 29  ? 0.27570 0.33800 0.15040 -0.03270 0.03810  -0.00370 32  PRO A C   
103  O O   . PRO A 29  ? 0.27480 0.31580 0.17420 -0.00230 0.04000  0.00920  32  PRO A O   
104  C CB  . PRO A 29  ? 0.33370 0.38930 0.24060 -0.06670 0.02020  0.01370  32  PRO A CB  
105  C CG  . PRO A 29  ? 0.33880 0.39150 0.28240 -0.06880 0.00830  0.01490  32  PRO A CG  
106  C CD  . PRO A 29  ? 0.33800 0.38770 0.23520 -0.07110 -0.00710 0.01800  32  PRO A CD  
114  N N   . PHE A 30  ? 0.28200 0.32360 0.14930 -0.00080 -0.03190 -0.01110 33  PHE A N   
115  C CA  . PHE A 30  ? 0.24050 0.30280 0.18060 0.02990  -0.04080 -0.02540 33  PHE A CA  
116  C C   . PHE A 30  ? 0.23580 0.30000 0.21250 0.04560  -0.05720 -0.04370 33  PHE A C   
117  O O   . PHE A 30  ? 0.23240 0.28430 0.20740 0.03350  -0.05240 -0.04990 33  PHE A O   
118  C CB  . PHE A 30  ? 0.23870 0.29680 0.19530 0.04350  -0.03840 -0.02870 33  PHE A CB  
119  C CG  . PHE A 30  ? 0.21650 0.28800 0.16390 0.03840  -0.03110 -0.01360 33  PHE A CG  
120  C CD1 . PHE A 30  ? 0.22620 0.28370 0.17360 0.02820  -0.02010 -0.02940 33  PHE A CD1 
121  C CD2 . PHE A 30  ? 0.23050 0.29270 0.17770 0.02140  -0.00880 -0.02040 33  PHE A CD2 
122  C CE1 . PHE A 30  ? 0.20840 0.28560 0.19590 0.01480  -0.00830 -0.01850 33  PHE A CE1 
123  C CE2 . PHE A 30  ? 0.23680 0.29190 0.19680 0.00370  0.04650  0.00110  33  PHE A CE2 
124  C CZ  . PHE A 30  ? 0.19770 0.28320 0.19840 0.01220  0.01560  -0.01160 33  PHE A CZ  
134  N N   . ALA A 31  ? 0.26050 0.31010 0.22100 0.04480  -0.06500 -0.04970 34  ALA A N   
135  C CA  . ALA A 31  ? 0.25310 0.32870 0.21960 0.03600  -0.07860 -0.04710 34  ALA A CA  
136  C C   . ALA A 31  ? 0.27020 0.33380 0.21220 0.02390  -0.05460 -0.06460 34  ALA A C   
137  O O   . ALA A 31  ? 0.24230 0.33710 0.20850 0.00540  -0.03360 -0.06990 34  ALA A O   
138  C CB  . ALA A 31  ? 0.26060 0.33460 0.24360 0.02940  -0.08970 -0.04720 34  ALA A CB  
144  N N   . LYS A 32  ? 0.29880 0.33310 0.19980 0.03310  -0.04070 -0.07450 35  LYS A N   
145  C CA  . LYS A 32  ? 0.29880 0.33330 0.18870 0.04520  -0.01800 -0.07790 35  LYS A CA  
146  C C   . LYS A 32  ? 0.27440 0.31910 0.20170 0.03560  -0.02490 -0.05340 35  LYS A C   
147  O O   . LYS A 32  ? 0.28860 0.31450 0.21760 0.03620  -0.02220 -0.06140 35  LYS A O   
148  C CB  . LYS A 32  ? 0.35000 0.36120 0.25260 0.05030  -0.01640 -0.08800 35  LYS A CB  
149  C CG  . LYS A 32  ? 0.40130 0.39300 0.33490 0.05570  -0.00780 -0.09400 35  LYS A CG  
150  C CD  . LYS A 32  ? 0.44540 0.41920 0.41740 0.06870  -0.00300 -0.09760 35  LYS A CD  
151  C CE  . LYS A 32  ? 0.47750 0.44040 0.47850 0.07600  -0.00290 -0.09100 35  LYS A CE  
152  N NZ  . LYS A 32  ? 0.49310 0.45020 0.50550 0.08060  -0.00110 -0.09660 35  LYS A NZ  
166  N N   . LEU A 33  ? 0.23510 0.30690 0.20030 0.03230  -0.03020 -0.04320 36  LEU A N   
167  C CA  . LEU A 33  ? 0.20990 0.29480 0.19650 0.03750  -0.02920 -0.03200 36  LEU A CA  
168  C C   . LEU A 33  ? 0.18840 0.27720 0.21150 0.04040  -0.03340 -0.03310 36  LEU A C   
169  O O   . LEU A 33  ? 0.16550 0.27580 0.19530 0.03730  -0.01340 -0.04430 36  LEU A O   
170  C CB  . LEU A 33  ? 0.18830 0.30390 0.20680 0.03300  -0.03110 -0.01890 36  LEU A CB  
171  C CG  . LEU A 33  ? 0.20430 0.31020 0.19800 0.03320  -0.02180 -0.01490 36  LEU A CG  
172  C CD1 . LEU A 33  ? 0.23290 0.31910 0.22640 0.02100  -0.02370 -0.02220 36  LEU A CD1 
173  C CD2 . LEU A 33  ? 0.19530 0.31230 0.19950 0.03180  0.00040  0.00300  36  LEU A CD2 
185  N N   . GLU A 34  ? 0.21260 0.27500 0.24320 0.04540  -0.04740 -0.02590 37  GLU A N   
186  C CA  . GLU A 34  ? 0.21260 0.28340 0.29920 0.04720  -0.02610 -0.01970 37  GLU A CA  
187  C C   . GLU A 34  ? 0.21760 0.28800 0.29980 0.02580  -0.04160 -0.02440 37  GLU A C   
188  O O   . GLU A 34  ? 0.21770 0.27080 0.29840 0.01720  -0.04290 -0.00720 37  GLU A O   
189  C CB  . GLU A 34  ? 0.26110 0.29560 0.32240 0.03750  -0.01290 -0.03050 37  GLU A CB  
190  C CG  . GLU A 34  ? 0.23360 0.29470 0.25590 0.05310  -0.03870 -0.02050 37  GLU A CG  
191  C CD  . GLU A 34  ? 0.16790 0.29230 0.17850 0.04300  0.00960  -0.03250 37  GLU A CD  
192  O OE1 . GLU A 34  ? 0.15420 0.27580 0.14640 0.02950  -0.01020 -0.01550 37  GLU A OE1 
193  O OE2 . GLU A 34  ? 0.17520 0.31420 0.15610 0.03310  -0.00390 -0.04420 37  GLU A OE2 
200  N N   . GLN A 35  ? 0.24190 0.29410 0.32990 0.01240  -0.05450 -0.04130 38  GLN A N   
201  C CA  . GLN A 35  ? 0.30870 0.30420 0.32180 0.02600  -0.06450 -0.06010 38  GLN A CA  
202  C C   . GLN A 35  ? 0.30700 0.29040 0.27230 0.02740  -0.05420 -0.06550 38  GLN A C   
203  O O   . GLN A 35  ? 0.31980 0.28990 0.29100 0.03380  -0.05660 -0.05440 38  GLN A O   
204  C CB  . GLN A 35  ? 0.36450 0.33360 0.36600 0.03470  -0.06440 -0.04860 38  GLN A CB  
205  C CG  . GLN A 35  ? 0.41890 0.36430 0.39590 0.05470  -0.06140 -0.05230 38  GLN A CG  
206  C CD  . GLN A 35  ? 0.45620 0.39090 0.41690 0.07050  -0.05970 -0.05890 38  GLN A CD  
207  O OE1 . GLN A 35  ? 0.46880 0.40280 0.42940 0.08280  -0.05540 -0.07060 38  GLN A OE1 
208  N NE2 . GLN A 35  ? 0.46730 0.40020 0.42850 0.07190  -0.05980 -0.05260 38  GLN A NE2 
217  N N   . ASP A 36  ? 0.30440 0.28610 0.21810 0.03640  -0.00590 -0.07120 39  ASP A N   
218  C CA  . ASP A 36  ? 0.29970 0.29940 0.21640 0.04100  0.02840  -0.05530 39  ASP A CA  
219  C C   . ASP A 36  ? 0.26250 0.28270 0.19480 0.04840  0.02650  -0.03440 39  ASP A C   
220  O O   . ASP A 36  ? 0.28620 0.29040 0.23960 0.04600  0.04360  -0.03780 39  ASP A O   
221  C CB  . ASP A 36  ? 0.33810 0.34050 0.23390 0.04690  0.06320  -0.05610 39  ASP A CB  
222  C CG  . ASP A 36  ? 0.40300 0.37840 0.29520 0.03850  0.05930  -0.05240 39  ASP A CG  
223  O OD1 . ASP A 36  ? 0.45390 0.39100 0.32750 0.04630  0.07490  -0.07320 39  ASP A OD1 
224  O OD2 . ASP A 36  ? 0.41440 0.39650 0.30060 0.04450  0.09420  -0.02800 39  ASP A OD2 
229  N N   . PHE A 37  ? 0.22570 0.26370 0.18410 0.03320  0.02820  -0.03360 40  PHE A N   
230  C CA  . PHE A 37  ? 0.21630 0.26670 0.18690 0.01930  0.00130  -0.02910 40  PHE A CA  
231  C C   . PHE A 37  ? 0.21810 0.27080 0.20830 0.01520  0.01070  -0.02870 40  PHE A C   
232  O O   . PHE A 37  ? 0.22220 0.28320 0.25480 0.00200  0.00020  -0.01030 40  PHE A O   
233  C CB  . PHE A 37  ? 0.20410 0.26200 0.17940 0.00670  0.00350  -0.04110 40  PHE A CB  
234  C CG  . PHE A 37  ? 0.17800 0.25980 0.19290 -0.00430 0.02390  -0.05850 40  PHE A CG  
235  C CD1 . PHE A 37  ? 0.19590 0.25110 0.19440 -0.00320 0.03660  -0.05870 40  PHE A CD1 
236  C CD2 . PHE A 37  ? 0.18180 0.26510 0.20950 -0.01100 0.01140  -0.06480 40  PHE A CD2 
237  C CE1 . PHE A 37  ? 0.20060 0.25870 0.19910 -0.00040 0.02200  -0.05440 40  PHE A CE1 
238  C CE2 . PHE A 37  ? 0.18010 0.26310 0.21700 -0.01710 0.01910  -0.05860 40  PHE A CE2 
239  C CZ  . PHE A 37  ? 0.20490 0.26470 0.20130 -0.00820 0.01720  -0.04960 40  PHE A CZ  
249  N N   . GLY A 38  ? 0.21940 0.26300 0.22760 0.00800  0.01770  -0.04990 41  GLY A N   
250  C CA  . GLY A 38  ? 0.22410 0.26780 0.25100 -0.00610 0.05280  -0.03260 41  GLY A CA  
251  C C   . GLY A 38  ? 0.21480 0.26890 0.26150 -0.00230 0.04560  -0.00570 41  GLY A C   
252  O O   . GLY A 38  ? 0.24400 0.27340 0.31300 0.01360  0.07630  0.00870  41  GLY A O   
256  N N   . GLY A 39  ? 0.18230 0.25500 0.18320 0.00080  0.01200  -0.00550 42  GLY A N   
257  C CA  . GLY A 39  ? 0.18310 0.25540 0.17960 0.00900  0.00910  -0.02350 42  GLY A CA  
258  C C   . GLY A 39  ? 0.20010 0.25250 0.15410 0.00770  0.01400  -0.04090 42  GLY A C   
259  O O   . GLY A 39  ? 0.27710 0.27310 0.16730 0.02170  0.01080  -0.05790 42  GLY A O   
263  N N   . SER A 40  ? 0.16880 0.23080 0.14100 -0.00910 0.00900  -0.02750 43  SER A N   
264  C CA  . SER A 40  ? 0.17050 0.23410 0.14430 -0.01360 0.00060  -0.02750 43  SER A CA  
265  C C   . SER A 40  ? 0.14420 0.24150 0.14350 -0.01110 -0.00030 -0.02320 43  SER A C   
266  O O   . SER A 40  ? 0.14460 0.25790 0.11870 -0.00420 0.00020  -0.00780 43  SER A O   
267  C CB  . SER A 40  ? 0.17540 0.24680 0.17390 -0.01790 0.00550  -0.03390 43  SER A CB  
268  O OG  . SER A 40  ? 0.17890 0.27850 0.20340 -0.02540 0.00180  -0.03180 43  SER A OG  
274  N N   . ILE A 41  ? 0.13620 0.22860 0.12400 -0.00310 0.00560  -0.02010 44  ILE A N   
275  C CA  . ILE A 41  ? 0.12870 0.22250 0.13120 -0.00610 -0.00220 -0.02070 44  ILE A CA  
276  C C   . ILE A 41  ? 0.09900 0.22810 0.12770 -0.00100 -0.00160 -0.00130 44  ILE A C   
277  O O   . ILE A 41  ? 0.15080 0.24860 0.13860 0.01550  -0.03820 -0.00340 44  ILE A O   
278  C CB  . ILE A 41  ? 0.11630 0.22310 0.18030 -0.01020 0.01110  -0.03430 44  ILE A CB  
279  C CG1 . ILE A 41  ? 0.15250 0.21600 0.21310 -0.01250 0.01490  -0.03920 44  ILE A CG1 
280  C CG2 . ILE A 41  ? 0.13540 0.25300 0.23060 0.00130  0.01900  -0.04870 44  ILE A CG2 
281  C CD1 . ILE A 41  ? 0.18070 0.22590 0.21990 0.00370  0.00990  -0.04180 44  ILE A CD1 
293  N N   . GLY A 42  ? 0.10230 0.22090 0.10100 -0.00440 0.00810  -0.00910 45  GLY A N   
294  C CA  . GLY A 42  ? 0.13460 0.22700 0.11530 0.00830  -0.00770 -0.01270 45  GLY A CA  
295  C C   . GLY A 42  ? 0.10480 0.22580 0.11130 0.00680  0.00260  -0.00780 45  GLY A C   
296  O O   . GLY A 42  ? 0.11270 0.22440 0.11720 -0.01950 -0.00270 0.01550  45  GLY A O   
300  N N   . VAL A 43  ? 0.12590 0.22570 0.12110 -0.01840 -0.00410 0.01600  46  VAL A N   
301  C CA  . VAL A 43  ? 0.14640 0.24130 0.11080 -0.01650 0.00070  0.02100  46  VAL A CA  
302  C C   . VAL A 43  ? 0.13840 0.24240 0.10270 -0.01570 0.00340  0.02240  46  VAL A C   
303  O O   . VAL A 43  ? 0.11360 0.26950 0.10830 -0.01070 -0.00540 0.02700  46  VAL A O   
304  C CB  . VAL A 43  ? 0.13170 0.24750 0.13330 0.00350  0.01030  0.03130  46  VAL A CB  
305  C CG1 . VAL A 43  ? 0.13720 0.26560 0.15610 0.00790  0.01250  0.03250  46  VAL A CG1 
306  C CG2 . VAL A 43  ? 0.16260 0.24300 0.14960 0.01180  0.03350  0.04030  46  VAL A CG2 
316  N N   A TYR A 44  ? 0.12820 0.23510 0.11180 0.00180  -0.02110 0.03220  47  TYR A N   
317  N N   B TYR A 44  ? 0.13640 0.23080 0.11550 -0.00490 -0.01810 0.03190  47  TYR A N   
318  C CA  A TYR A 44  ? 0.13990 0.22450 0.12120 -0.00700 -0.01040 0.02560  47  TYR A CA  
319  C CA  B TYR A 44  ? 0.14880 0.21560 0.12420 -0.01100 0.00090  0.02950  47  TYR A CA  
320  C C   A TYR A 44  ? 0.12740 0.22970 0.13550 -0.02870 -0.00680 0.02670  47  TYR A C   
321  C C   B TYR A 44  ? 0.14330 0.22120 0.12760 -0.01950 0.00370  0.03190  47  TYR A C   
322  O O   A TYR A 44  ? 0.09810 0.23850 0.13300 -0.02860 -0.02640 0.02520  47  TYR A O   
323  O O   B TYR A 44  ? 0.15060 0.21230 0.11350 -0.00190 -0.00450 0.05250  47  TYR A O   
324  C CB  A TYR A 44  ? 0.13480 0.21560 0.12220 -0.00240 -0.01190 0.01710  47  TYR A CB  
325  C CB  B TYR A 44  ? 0.14390 0.20180 0.13100 -0.01850 0.01620  0.02230  47  TYR A CB  
326  C CG  A TYR A 44  ? 0.12260 0.21160 0.10910 0.00150  0.00520  0.01310  47  TYR A CG  
327  C CG  B TYR A 44  ? 0.15090 0.19800 0.13260 -0.02330 0.02970  0.02880  47  TYR A CG  
328  C CD1 A TYR A 44  ? 0.13200 0.20560 0.10920 -0.00650 0.00060  0.01250  47  TYR A CD1 
329  C CD1 B TYR A 44  ? 0.16530 0.19590 0.13160 -0.02080 0.01850  0.02990  47  TYR A CD1 
330  C CD2 A TYR A 44  ? 0.14150 0.21520 0.11680 -0.00090 -0.00240 0.00710  47  TYR A CD2 
331  C CD2 B TYR A 44  ? 0.17400 0.19930 0.15390 -0.03320 0.02550  0.03560  47  TYR A CD2 
332  C CE1 A TYR A 44  ? 0.14910 0.20190 0.12570 -0.00340 -0.00420 0.01270  47  TYR A CE1 
333  C CE1 B TYR A 44  ? 0.17750 0.18770 0.12860 -0.01840 0.01770  0.02400  47  TYR A CE1 
334  C CE2 A TYR A 44  ? 0.15570 0.21750 0.13620 -0.01440 0.00980  0.00940  47  TYR A CE2 
335  C CE2 B TYR A 44  ? 0.17690 0.19530 0.14270 -0.03890 0.00260  0.03180  47  TYR A CE2 
336  C CZ  A TYR A 44  ? 0.14500 0.21090 0.12430 -0.02210 -0.00890 0.01760  47  TYR A CZ  
337  C CZ  B TYR A 44  ? 0.18350 0.19210 0.14330 -0.02900 0.01600  0.02940  47  TYR A CZ  
338  O OH  A TYR A 44  ? 0.14530 0.22220 0.16640 -0.01780 -0.01740 0.02420  47  TYR A OH  
339  O OH  B TYR A 44  ? 0.21340 0.21460 0.19230 -0.03970 0.01420  0.01260  47  TYR A OH  
358  N N   . ALA A 45  ? 0.13230 0.23340 0.12150 -0.02190 0.01500  0.02910  48  ALA A N   
359  C CA  . ALA A 45  ? 0.13950 0.23280 0.11860 -0.00890 0.01970  0.03680  48  ALA A CA  
360  C C   . ALA A 45  ? 0.14360 0.25190 0.13190 -0.01160 0.02490  0.04360  48  ALA A C   
361  O O   . ALA A 45  ? 0.17050 0.28480 0.12810 -0.02020 -0.01510 0.04100  48  ALA A O   
362  C CB  . ALA A 45  ? 0.14550 0.23080 0.10270 -0.00850 0.01830  0.04000  48  ALA A CB  
369  N N   A MET A 46  ? 0.14040 0.23920 0.14520 -0.01210 0.02400  0.05370  49  MET A N   
370  N N   B MET A 46  ? 0.14060 0.25560 0.15680 -0.00460 -0.01250 0.04230  49  MET A N   
371  C CA  A MET A 46  ? 0.15750 0.23890 0.17320 -0.01160 0.01180  0.05380  49  MET A CA  
372  C CA  B MET A 46  ? 0.15960 0.27610 0.20550 -0.01710 -0.02810 0.02260  49  MET A CA  
373  C C   A MET A 46  ? 0.15580 0.24890 0.17220 -0.01110 0.01710  0.05720  49  MET A C   
374  C C   B MET A 46  ? 0.15140 0.26320 0.18470 -0.02190 -0.00520 0.03220  49  MET A C   
375  O O   A MET A 46  ? 0.15220 0.24170 0.16820 -0.00290 0.02360  0.07410  49  MET A O   
376  O O   B MET A 46  ? 0.12840 0.23440 0.16880 -0.02570 -0.01220 0.03450  49  MET A O   
377  C CB  A MET A 46  ? 0.17630 0.23730 0.20010 -0.01160 0.03170  0.05520  49  MET A CB  
378  C CB  B MET A 46  ? 0.20610 0.31960 0.29560 -0.02090 0.00990  -0.00070 49  MET A CB  
379  C CG  A MET A 46  ? 0.20830 0.25280 0.21420 -0.00320 0.02990  0.04520  49  MET A CG  
380  C CG  B MET A 46  ? 0.23790 0.37540 0.35650 -0.02810 0.04200  -0.02780 49  MET A CG  
381  S SD  A MET A 46  ? 0.23590 0.26150 0.21410 -0.00790 0.03210  0.03440  49  MET A SD  
382  S SD  B MET A 46  ? 0.25360 0.42330 0.40080 -0.03290 0.06060  -0.06880 49  MET A SD  
383  C CE  A MET A 46  ? 0.23240 0.25590 0.22170 -0.01350 0.02480  0.03570  49  MET A CE  
384  C CE  B MET A 46  ? 0.20660 0.41540 0.37130 -0.05250 0.06670  -0.07650 49  MET A CE  
403  N N   . ASP A 47  ? 0.15610 0.26300 0.16510 -0.01730 0.00480  0.06040  50  ASP A N   
404  C CA  . ASP A 47  ? 0.17570 0.28850 0.17010 -0.01890 0.01140  0.06050  50  ASP A CA  
405  C C   . ASP A 47  ? 0.15980 0.28630 0.19210 -0.01820 0.00930  0.07810  50  ASP A C   
406  O O   . ASP A 47  ? 0.17060 0.29090 0.20710 -0.00840 -0.02260 0.09220  50  ASP A O   
407  C CB  . ASP A 47  ? 0.19590 0.31190 0.17390 -0.01290 0.01850  0.06070  50  ASP A CB  
408  C CG  . ASP A 47  ? 0.21150 0.33830 0.20840 -0.00880 0.02970  0.05760  50  ASP A CG  
409  O OD1 . ASP A 47  ? 0.21700 0.33410 0.21500 -0.02250 0.06250  0.06260  50  ASP A OD1 
410  O OD2 . ASP A 47  ? 0.21270 0.35960 0.22360 0.00230  0.04760  0.06500  50  ASP A OD2 
416  N N   . THR A 48  ? 0.13210 0.28130 0.19030 -0.00010 0.01750  0.06110  51  THR A N   
417  C CA  . THR A 48  ? 0.17110 0.26640 0.22390 0.00320  0.01740  0.06790  51  THR A CA  
418  C C   . THR A 48  ? 0.23940 0.26730 0.25840 0.01710  0.01980  0.07570  51  THR A C   
419  O O   . THR A 48  ? 0.28090 0.27090 0.29580 0.03250  0.03260  0.06740  51  THR A O   
420  C CB  . THR A 48  ? 0.17030 0.26950 0.23460 0.00310  0.02060  0.04090  51  THR A CB  
421  O OG1 . THR A 48  ? 0.16810 0.25400 0.24640 0.02120  0.01760  0.04040  51  THR A OG1 
422  C CG2 . THR A 48  ? 0.15590 0.28540 0.21820 0.00420  0.03590  0.03310  51  THR A CG2 
430  N N   . GLY A 49  ? 0.22650 0.26930 0.24030 0.01240  0.01940  0.10710  52  GLY A N   
431  C CA  . GLY A 49  ? 0.27070 0.28590 0.28190 -0.00660 -0.00120 0.10790  52  GLY A CA  
432  C C   . GLY A 49  ? 0.30510 0.30850 0.31190 -0.00710 -0.02700 0.11710  52  GLY A C   
433  O O   . GLY A 49  ? 0.34980 0.32390 0.36000 -0.00690 -0.06730 0.10110  52  GLY A O   
437  N N   . SER A 50  ? 0.30370 0.32350 0.30060 -0.00100 -0.03770 0.12000  53  SER A N   
438  C CA  . SER A 50  ? 0.30080 0.34660 0.28520 0.00020  -0.03790 0.11880  53  SER A CA  
439  C C   . SER A 50  ? 0.30380 0.35490 0.30990 0.00740  -0.05230 0.13470  53  SER A C   
440  O O   . SER A 50  ? 0.34100 0.36950 0.33580 0.01280  -0.08160 0.13800  53  SER A O   
441  C CB  . SER A 50  ? 0.31670 0.35710 0.25810 -0.01870 -0.01470 0.09850  53  SER A CB  
442  O OG  . SER A 50  ? 0.33050 0.36440 0.23040 -0.04240 0.00790  0.09050  53  SER A OG  
448  N N   . GLY A 51  ? 0.28650 0.35120 0.31610 0.00580  -0.02800 0.13400  54  GLY A N   
449  C CA  . GLY A 51  ? 0.27610 0.36450 0.34260 0.02120  -0.02230 0.13010  54  GLY A CA  
450  C C   . GLY A 51  ? 0.25850 0.37280 0.32850 0.01190  -0.02380 0.12760  54  GLY A C   
451  O O   . GLY A 51  ? 0.24800 0.38480 0.37560 0.01430  -0.01350 0.11230  54  GLY A O   
455  N N   . ALA A 52  ? 0.25420 0.37650 0.26740 -0.00790 -0.02590 0.13070  55  ALA A N   
456  C CA  . ALA A 52  ? 0.24730 0.37870 0.23230 -0.01830 -0.00980 0.12960  55  ALA A CA  
457  C C   . ALA A 52  ? 0.20180 0.38590 0.18870 -0.01740 -0.02300 0.09960  55  ALA A C   
458  O O   . ALA A 52  ? 0.17420 0.39100 0.18520 -0.01080 -0.02510 0.08560  55  ALA A O   
459  C CB  . ALA A 52  ? 0.28050 0.38290 0.24180 -0.02340 -0.00090 0.13090  55  ALA A CB  
465  N N   . THR A 53  ? 0.17490 0.38190 0.19870 -0.01740 -0.03570 0.09420  56  THR A N   
466  C CA  . THR A 53  ? 0.17000 0.38160 0.19330 -0.03490 -0.02000 0.08860  56  THR A CA  
467  C C   . THR A 53  ? 0.18970 0.37840 0.14520 -0.04580 -0.02280 0.07270  56  THR A C   
468  O O   . THR A 53  ? 0.25080 0.40510 0.13880 -0.05170 -0.01960 0.07810  56  THR A O   
469  C CB  . THR A 53  ? 0.16670 0.39330 0.24560 0.00040  -0.04150 0.05640  56  THR A CB  
470  O OG1 . THR A 53  ? 0.18070 0.40620 0.28700 0.00220  -0.03470 0.06150  56  THR A OG1 
471  C CG2 . THR A 53  ? 0.16540 0.39780 0.25970 0.00410  -0.00650 0.05680  56  THR A CG2 
479  N N   . VAL A 54  ? 0.16770 0.34810 0.14320 -0.05040 -0.01790 0.05050  57  VAL A N   
480  C CA  . VAL A 54  ? 0.15450 0.32750 0.13740 -0.05510 0.00850  0.04150  57  VAL A CA  
481  C C   . VAL A 54  ? 0.16570 0.30020 0.11930 -0.02520 0.00180  0.04260  57  VAL A C   
482  O O   . VAL A 54  ? 0.15600 0.30370 0.12640 -0.01780 0.00130  0.04120  57  VAL A O   
483  C CB  . VAL A 54  ? 0.14450 0.34340 0.14250 -0.04170 0.01710  0.01820  57  VAL A CB  
484  C CG1 . VAL A 54  ? 0.12810 0.35530 0.17340 -0.01830 0.00510  0.01110  57  VAL A CG1 
485  C CG2 . VAL A 54  ? 0.18410 0.35490 0.15930 -0.05810 0.01920  0.01140  57  VAL A CG2 
495  N N   . SER A 55  ? 0.14800 0.28360 0.11370 -0.01270 -0.00720 0.01970  59  SER A N   
496  C CA  A SER A 55  ? 0.16350 0.28520 0.10240 -0.01170 0.00200  0.02730  59  SER A CA  
497  C CA  B SER A 55  ? 0.16790 0.28370 0.10740 -0.00980 0.00410  0.01250  59  SER A CA  
498  C C   . SER A 55  ? 0.19310 0.28700 0.11280 -0.01190 0.00750  0.01290  59  SER A C   
499  O O   . SER A 55  ? 0.26010 0.30790 0.11990 -0.03710 0.01870  0.01940  59  SER A O   
500  C CB  A SER A 55  ? 0.18740 0.29630 0.13040 -0.00570 -0.00250 0.02900  59  SER A CB  
501  C CB  B SER A 55  ? 0.18440 0.28460 0.12290 -0.00130 0.00300  -0.00390 59  SER A CB  
502  O OG  A SER A 55  ? 0.19970 0.31310 0.13790 -0.01490 0.00430  0.03170  59  SER A OG  
503  O OG  B SER A 55  ? 0.20280 0.28890 0.12530 -0.00580 0.00070  -0.02980 59  SER A OG  
514  N N   . TYR A 56  ? 0.16550 0.27510 0.11470 -0.00070 -0.00400 0.00240  60  TYR A N   
515  C CA  . TYR A 56  ? 0.14880 0.26990 0.12230 0.00880  0.00900  -0.01520 60  TYR A CA  
516  C C   . TYR A 56  ? 0.12030 0.25970 0.13390 -0.00250 0.00320  -0.00810 60  TYR A C   
517  O O   . TYR A 56  ? 0.12800 0.26940 0.11460 0.00780  -0.01010 -0.02460 60  TYR A O   
518  C CB  . TYR A 56  ? 0.17650 0.28010 0.12190 0.01620  0.03510  -0.02020 60  TYR A CB  
519  C CG  . TYR A 56  ? 0.18700 0.28970 0.13420 0.01370  -0.00440 -0.03860 60  TYR A CG  
520  C CD1 . TYR A 56  ? 0.24870 0.29210 0.12750 0.02010  0.00440  -0.04780 60  TYR A CD1 
521  C CD2 . TYR A 56  ? 0.16700 0.27070 0.13970 0.02670  -0.00330 -0.04290 60  TYR A CD2 
522  C CE1 . TYR A 56  ? 0.25110 0.28710 0.12640 0.02320  -0.02290 -0.04650 60  TYR A CE1 
523  C CE2 . TYR A 56  ? 0.17440 0.27210 0.15680 0.03180  -0.00830 -0.04450 60  TYR A CE2 
524  C CZ  . TYR A 56  ? 0.22760 0.27990 0.14250 0.02280  0.00900  -0.05650 60  TYR A CZ  
525  O OH  . TYR A 56  ? 0.26800 0.29760 0.15500 0.02280  -0.01160 -0.05210 60  TYR A OH  
535  N N   . ARG A 57  ? 0.12480 0.24030 0.09820 -0.00310 -0.00560 -0.00230 61  ARG A N   
536  C CA  . ARG A 57  ? 0.11890 0.22170 0.11220 0.00530  -0.01630 0.00990  61  ARG A CA  
537  C C   . ARG A 57  ? 0.11150 0.22450 0.10140 0.00170  -0.00970 0.01780  61  ARG A C   
538  O O   . ARG A 57  ? 0.12350 0.23220 0.10210 0.01960  -0.00240 0.01670  61  ARG A O   
539  C CB  . ARG A 57  ? 0.13440 0.20620 0.11280 0.02080  -0.00190 0.00000  61  ARG A CB  
540  C CG  . ARG A 57  ? 0.13280 0.22170 0.12260 0.00580  0.00610  -0.00430 61  ARG A CG  
541  C CD  . ARG A 57  ? 0.16630 0.23730 0.13900 -0.00760 0.01090  -0.00020 61  ARG A CD  
542  N NE  . ARG A 57  ? 0.15890 0.24910 0.14790 0.00750  -0.00850 -0.01910 61  ARG A NE  
543  C CZ  . ARG A 57  ? 0.16670 0.26320 0.16510 0.01000  0.00980  -0.05570 61  ARG A CZ  
544  N NH1 . ARG A 57  ? 0.15940 0.27480 0.17920 0.01520  -0.01230 -0.05620 61  ARG A NH1 
545  N NH2 . ARG A 57  ? 0.18970 0.27670 0.19860 0.01760  0.00390  -0.05390 61  ARG A NH2 
559  N N   . ALA A 58  ? 0.12890 0.22630 0.11460 0.00680  0.00020  0.03210  62  ALA A N   
560  C CA  . ALA A 58  ? 0.12940 0.23470 0.11700 0.01870  -0.00310 0.01460  62  ALA A CA  
561  C C   . ALA A 58  ? 0.14640 0.22820 0.11110 0.02830  -0.00980 0.00550  62  ALA A C   
562  O O   . ALA A 58  ? 0.14090 0.23680 0.09960 0.00410  -0.00110 -0.00770 62  ALA A O   
563  C CB  . ALA A 58  ? 0.13940 0.23630 0.12830 0.02030  0.00400  0.01330  62  ALA A CB  
569  N N   . GLU A 59  ? 0.13260 0.22270 0.11620 0.03090  -0.00940 0.00140  63  GLU A N   
570  C CA  . GLU A 59  ? 0.12830 0.22890 0.13380 0.02690  0.00760  0.02420  63  GLU A CA  
571  C C   . GLU A 59  ? 0.12890 0.22920 0.12810 0.01800  0.00020  0.02270  63  GLU A C   
572  O O   . GLU A 59  ? 0.15710 0.23920 0.16780 0.04010  0.03400  0.03870  63  GLU A O   
573  C CB  . GLU A 59  ? 0.15050 0.23830 0.15460 0.03820  0.00620  0.02990  63  GLU A CB  
574  C CG  . GLU A 59  ? 0.17570 0.25330 0.15970 0.03720  -0.01770 0.02300  63  GLU A CG  
575  C CD  . GLU A 59  ? 0.16780 0.26020 0.16770 0.02680  -0.00770 0.01740  63  GLU A CD  
576  O OE1 . GLU A 59  ? 0.19110 0.25770 0.13540 0.01030  0.00030  0.01450  63  GLU A OE1 
577  O OE2 . GLU A 59  ? 0.17580 0.26500 0.14580 0.00870  -0.02370 -0.00280 63  GLU A OE2 
584  N N   . GLU A 60  ? 0.11250 0.22990 0.12410 0.00830  0.00010  0.01670  64  GLU A N   
585  C CA  . GLU A 60  ? 0.13030 0.23210 0.11200 0.00260  -0.01140 -0.00010 64  GLU A CA  
586  C C   . GLU A 60  ? 0.12500 0.23800 0.12440 0.00030  -0.02240 0.00020  64  GLU A C   
587  O O   . GLU A 60  ? 0.12940 0.21310 0.11300 -0.01960 -0.00670 -0.00240 64  GLU A O   
588  C CB  . GLU A 60  ? 0.12610 0.24710 0.13400 0.00040  -0.00420 -0.01510 64  GLU A CB  
589  C CG  . GLU A 60  ? 0.15260 0.25760 0.11400 0.00650  -0.01120 -0.00900 64  GLU A CG  
590  C CD  . GLU A 60  ? 0.19010 0.26390 0.11610 0.01100  -0.02030 -0.00190 64  GLU A CD  
591  O OE1 . GLU A 60  ? 0.27850 0.25750 0.11510 0.02590  -0.01580 0.00910  64  GLU A OE1 
592  O OE2 . GLU A 60  ? 0.15060 0.27750 0.12160 0.01490  -0.02010 -0.01340 64  GLU A OE2 
599  N N   . ARG A 61  ? 0.12140 0.23200 0.11660 0.00160  -0.01960 0.00130  65  ARG A N   
600  C CA  . ARG A 61  ? 0.11820 0.23120 0.11510 0.00360  0.00080  -0.00940 65  ARG A CA  
601  C C   . ARG A 61  ? 0.12550 0.22760 0.11740 -0.00290 0.00350  -0.02090 65  ARG A C   
602  O O   . ARG A 61  ? 0.12390 0.21910 0.12040 0.00180  -0.00990 -0.01060 65  ARG A O   
603  C CB  . ARG A 61  ? 0.11650 0.21350 0.13880 0.00430  0.00460  -0.01140 65  ARG A CB  
604  C CG  . ARG A 61  ? 0.11230 0.21910 0.13400 -0.00000 0.00180  -0.01130 65  ARG A CG  
605  C CD  . ARG A 61  ? 0.13520 0.22950 0.14400 0.01290  -0.00660 -0.00890 65  ARG A CD  
606  N NE  . ARG A 61  ? 0.13820 0.22760 0.14840 -0.00850 -0.00170 -0.01430 65  ARG A NE  
607  C CZ  . ARG A 61  ? 0.13500 0.23120 0.14760 -0.00940 0.01470  -0.00010 65  ARG A CZ  
608  N NH1 . ARG A 61  ? 0.11620 0.22030 0.14230 -0.01470 -0.01070 0.01590  65  ARG A NH1 
609  N NH2 . ARG A 61  ? 0.11730 0.25160 0.16850 0.01000  -0.01200 0.00410  65  ARG A NH2 
623  N N   . PHE A 62  ? 0.09900 0.22250 0.10110 -0.00460 -0.01030 -0.01990 66  PHE A N   
624  C CA  . PHE A 62  ? 0.11110 0.20530 0.10510 -0.01900 -0.00090 -0.01940 66  PHE A CA  
625  C C   . PHE A 62  ? 0.12590 0.21320 0.11720 -0.02370 0.00660  -0.02930 66  PHE A C   
626  O O   . PHE A 62  ? 0.13640 0.19300 0.11370 -0.01590 0.00990  -0.02170 66  PHE A O   
627  C CB  . PHE A 62  ? 0.11340 0.19860 0.11230 -0.00870 0.00940  -0.00080 66  PHE A CB  
628  C CG  . PHE A 62  ? 0.11430 0.20930 0.10660 0.01000  0.01220  -0.00560 66  PHE A CG  
629  C CD1 . PHE A 62  ? 0.12490 0.21870 0.12630 0.00650  0.03500  -0.00040 66  PHE A CD1 
630  C CD2 . PHE A 62  ? 0.13080 0.21720 0.11480 -0.00040 0.00360  -0.01240 66  PHE A CD2 
631  C CE1 . PHE A 62  ? 0.11680 0.23120 0.12230 0.00940  0.01780  0.00370  66  PHE A CE1 
632  C CE2 . PHE A 62  ? 0.12110 0.21490 0.12740 0.00480  -0.00230 0.00120  66  PHE A CE2 
633  C CZ  . PHE A 62  ? 0.11520 0.21830 0.11680 -0.00170 -0.00750 0.01230  66  PHE A CZ  
643  N N   . PRO A 63  ? 0.11930 0.22550 0.09440 -0.01640 0.00010  0.00180  67  PRO A N   
644  C CA  . PRO A 63  ? 0.10960 0.22830 0.10840 -0.01090 -0.01160 -0.00270 67  PRO A CA  
645  C C   . PRO A 63  ? 0.11670 0.22190 0.10500 -0.01040 -0.00740 0.01520  67  PRO A C   
646  O O   . PRO A 63  ? 0.11130 0.22900 0.11130 -0.01630 0.00580  0.00900  67  PRO A O   
647  C CB  . PRO A 63  ? 0.11110 0.23540 0.10420 -0.00480 0.00590  0.00550  67  PRO A CB  
648  C CG  . PRO A 63  ? 0.11490 0.22910 0.12580 -0.01910 -0.01310 0.02010  67  PRO A CG  
649  C CD  . PRO A 63  ? 0.13210 0.22620 0.11960 -0.03370 -0.02830 -0.00960 67  PRO A CD  
657  N N   . LEU A 64  ? 0.12980 0.22750 0.09270 -0.01880 0.00610  0.00690  68  LEU A N   
658  C CA  . LEU A 64  ? 0.11480 0.21840 0.10550 0.00290  -0.00650 0.00320  68  LEU A CA  
659  C C   . LEU A 64  ? 0.12090 0.21640 0.09310 -0.00910 -0.00190 0.00580  68  LEU A C   
660  O O   . LEU A 64  ? 0.11850 0.22060 0.10660 -0.01020 0.00550  -0.00480 68  LEU A O   
661  C CB  . LEU A 64  ? 0.14260 0.21340 0.11240 0.00110  -0.00690 0.01250  68  LEU A CB  
662  C CG  . LEU A 64  ? 0.13480 0.21370 0.13040 0.00390  -0.01450 0.00800  68  LEU A CG  
663  C CD1 . LEU A 64  ? 0.14630 0.22920 0.13540 0.01900  -0.00390 -0.01180 68  LEU A CD1 
664  C CD2 . LEU A 64  ? 0.14990 0.19550 0.14640 0.02050  -0.03030 0.02690  68  LEU A CD2 
676  N N   . CYS A 65  ? 0.14260 0.22050 0.09140 0.00480  0.00270  -0.00230 69  CYS A N   
677  C CA  . CYS A 65  ? 0.12390 0.22550 0.11510 -0.00680 -0.00310 0.00030  69  CYS A CA  
678  C C   . CYS A 65  ? 0.16060 0.21870 0.10100 -0.00850 0.00500  -0.01070 69  CYS A C   
679  O O   . CYS A 65  ? 0.15880 0.22060 0.10420 -0.00230 -0.00740 -0.00650 69  CYS A O   
680  C CB  . CYS A 65  ? 0.11680 0.24140 0.12250 -0.00050 0.00030  -0.01340 69  CYS A CB  
681  S SG  . CYS A 65  ? 0.14430 0.20700 0.12140 -0.00310 -0.00920 -0.00250 69  CYS A SG  
686  N N   . SER A 66  ? 0.12920 0.21570 0.10210 -0.01220 -0.01050 0.00150  70  SER A N   
687  C CA  . SER A 66  ? 0.12650 0.21000 0.11030 -0.00760 -0.00800 0.01850  70  SER A CA  
688  C C   . SER A 66  ? 0.12430 0.21300 0.11410 -0.00010 -0.00770 0.01900  70  SER A C   
689  O O   . SER A 66  ? 0.11450 0.23150 0.13140 0.00050  -0.02570 0.01820  70  SER A O   
690  C CB  . SER A 66  ? 0.14370 0.21360 0.12050 -0.01710 -0.01590 0.02500  70  SER A CB  
691  O OG  . SER A 66  ? 0.17660 0.23690 0.11300 -0.00670 -0.02580 0.00740  70  SER A OG  
696  N N   . SER A 67  ? 0.10290 0.20620 0.10490 -0.02400 -0.00160 0.00360  71  SER A N   
697  C CA  . SER A 67  ? 0.13420 0.21620 0.10970 -0.02420 0.01170  0.00360  71  SER A CA  
698  C C   . SER A 67  ? 0.12900 0.23060 0.09840 -0.01490 -0.01200 0.02110  71  SER A C   
699  O O   . SER A 67  ? 0.13760 0.22570 0.10880 -0.00850 0.00010  0.02640  71  SER A O   
700  C CB  . SER A 67  ? 0.12930 0.20700 0.11250 0.00230  -0.01530 0.00520  71  SER A CB  
701  O OG  . SER A 67  ? 0.13200 0.23460 0.11840 0.01360  -0.00660 0.01650  71  SER A OG  
707  N N   . PHE A 68  ? 0.13560 0.23460 0.09600 -0.01580 -0.00030 -0.01690 72  PHE A N   
708  C CA  . PHE A 68  ? 0.14310 0.23180 0.11910 0.00130  -0.00440 -0.01650 72  PHE A CA  
709  C C   . PHE A 68  ? 0.14520 0.24520 0.11710 0.00130  -0.01110 -0.00630 72  PHE A C   
710  O O   . PHE A 68  ? 0.14510 0.24240 0.12430 -0.00310 0.00110  -0.01340 72  PHE A O   
711  C CB  . PHE A 68  ? 0.14190 0.23510 0.12140 -0.00680 0.01230  -0.01410 72  PHE A CB  
712  C CG  . PHE A 68  ? 0.14910 0.22770 0.13760 -0.01380 0.02290  -0.01470 72  PHE A CG  
713  C CD1 . PHE A 68  ? 0.17500 0.24150 0.13660 -0.02640 0.01640  -0.02420 72  PHE A CD1 
714  C CD2 . PHE A 68  ? 0.17510 0.23420 0.13220 -0.02300 0.03220  -0.01780 72  PHE A CD2 
715  C CE1 . PHE A 68  ? 0.17640 0.24360 0.16680 -0.01580 0.02420  -0.03410 72  PHE A CE1 
716  C CE2 . PHE A 68  ? 0.18350 0.24480 0.15290 -0.01320 0.01550  -0.04110 72  PHE A CE2 
717  C CZ  . PHE A 68  ? 0.17110 0.25010 0.15580 -0.02450 0.00140  -0.03540 72  PHE A CZ  
727  N N   . LYS A 69  ? 0.13080 0.24100 0.12990 -0.00740 -0.01070 -0.02120 73  LYS A N   
728  C CA  . LYS A 69  ? 0.12830 0.23680 0.13410 -0.01110 -0.00640 -0.02320 73  LYS A CA  
729  C C   . LYS A 69  ? 0.13470 0.22950 0.13370 -0.00960 -0.00790 -0.02890 73  LYS A C   
730  O O   . LYS A 69  ? 0.14360 0.23120 0.13760 -0.00140 -0.02760 -0.03610 73  LYS A O   
731  C CB  . LYS A 69  ? 0.15540 0.22470 0.13710 0.00110  -0.01480 -0.02180 73  LYS A CB  
732  C CG  . LYS A 69  ? 0.18070 0.21040 0.11470 0.01430  -0.01990 0.00410  73  LYS A CG  
733  C CD  . LYS A 69  ? 0.21660 0.20280 0.12260 0.01360  -0.01590 0.02400  73  LYS A CD  
734  C CE  . LYS A 69  ? 0.23510 0.19060 0.15470 0.01650  -0.02850 0.01910  73  LYS A CE  
735  N NZ  . LYS A 69  ? 0.26510 0.21190 0.16680 0.03530  -0.02320 0.01320  73  LYS A NZ  
749  N N   . GLY A 70  ? 0.12020 0.23130 0.13560 -0.01200 -0.00770 -0.02390 74  GLY A N   
750  C CA  . GLY A 70  ? 0.11450 0.22430 0.13390 -0.00880 -0.01300 -0.01950 74  GLY A CA  
751  C C   . GLY A 70  ? 0.14710 0.23750 0.11730 -0.01190 -0.02250 -0.02080 74  GLY A C   
752  O O   . GLY A 70  ? 0.14150 0.24590 0.12730 -0.01900 0.00050  -0.01990 74  GLY A O   
756  N N   . PHE A 71  ? 0.14730 0.22810 0.12620 0.00150  -0.03580 -0.01280 75  PHE A N   
757  C CA  . PHE A 71  ? 0.15690 0.24260 0.13730 0.00930  -0.02400 -0.01010 75  PHE A CA  
758  C C   . PHE A 71  ? 0.15200 0.25130 0.12730 0.01290  -0.01650 -0.02580 75  PHE A C   
759  O O   . PHE A 71  ? 0.16820 0.26100 0.12750 0.01130  -0.01140 -0.02900 75  PHE A O   
760  C CB  . PHE A 71  ? 0.16310 0.23380 0.13470 0.01850  -0.01560 -0.00980 75  PHE A CB  
761  C CG  . PHE A 71  ? 0.15010 0.20140 0.11570 0.01050  -0.00380 -0.00510 75  PHE A CG  
762  C CD1 . PHE A 71  ? 0.15610 0.19270 0.13060 -0.00330 0.00420  -0.00010 75  PHE A CD1 
763  C CD2 . PHE A 71  ? 0.13310 0.21720 0.12190 0.00250  0.00590  -0.03190 75  PHE A CD2 
764  C CE1 . PHE A 71  ? 0.15630 0.19960 0.15320 -0.00910 -0.00390 0.00320  75  PHE A CE1 
765  C CE2 . PHE A 71  ? 0.13430 0.21210 0.13870 0.00150  -0.00680 -0.01930 75  PHE A CE2 
766  C CZ  . PHE A 71  ? 0.13790 0.20000 0.13720 -0.01250 0.00740  -0.00510 75  PHE A CZ  
776  N N   . LEU A 72  ? 0.13670 0.25900 0.12940 0.00850  -0.01210 -0.03300 76  LEU A N   
777  C CA  . LEU A 72  ? 0.14520 0.26650 0.12090 0.00120  -0.00720 -0.03930 76  LEU A CA  
778  C C   . LEU A 72  ? 0.15170 0.26320 0.09670 -0.00750 -0.01710 -0.03370 76  LEU A C   
779  O O   . LEU A 72  ? 0.16080 0.26760 0.11090 -0.01700 -0.01630 -0.02090 76  LEU A O   
780  C CB  . LEU A 72  ? 0.16860 0.28070 0.12900 -0.00710 -0.01790 -0.01170 76  LEU A CB  
781  C CG  . LEU A 72  ? 0.22220 0.29710 0.13910 0.00120  -0.02690 -0.01020 76  LEU A CG  
782  C CD1 . LEU A 72  ? 0.20680 0.32060 0.16250 -0.00600 -0.01690 0.00750  76  LEU A CD1 
783  C CD2 . LEU A 72  ? 0.28610 0.30010 0.14330 -0.01430 -0.03850 -0.02130 76  LEU A CD2 
795  N N   . ALA A 73  ? 0.13950 0.26590 0.12190 -0.00370 -0.01100 -0.01650 77  ALA A N   
796  C CA  . ALA A 73  ? 0.16730 0.26000 0.13170 0.00020  -0.01580 -0.01720 77  ALA A CA  
797  C C   . ALA A 73  ? 0.14450 0.26460 0.13580 -0.00570 -0.00260 -0.02050 77  ALA A C   
798  O O   . ALA A 73  ? 0.16880 0.26360 0.15700 0.02430  -0.02020 -0.04760 77  ALA A O   
799  C CB  . ALA A 73  ? 0.17360 0.25840 0.13830 0.01470  -0.01100 -0.02550 77  ALA A CB  
805  N N   . ALA A 74  ? 0.13790 0.26190 0.15120 -0.01230 -0.01500 -0.02160 78  ALA A N   
806  C CA  . ALA A 74  ? 0.15720 0.25720 0.15610 -0.01070 -0.01990 -0.03070 78  ALA A CA  
807  C C   . ALA A 74  ? 0.18250 0.25690 0.15560 0.00310  -0.03170 -0.04360 78  ALA A C   
808  O O   . ALA A 74  ? 0.17960 0.26140 0.16330 0.01220  -0.02330 -0.05710 78  ALA A O   
809  C CB  . ALA A 74  ? 0.14950 0.26450 0.15490 -0.01340 0.00720  -0.00790 78  ALA A CB  
815  N N   . ALA A 75  ? 0.16630 0.24380 0.16410 0.02370  -0.03310 -0.06540 79  ALA A N   
816  C CA  . ALA A 75  ? 0.17630 0.24140 0.16820 0.00300  -0.01170 -0.06980 79  ALA A CA  
817  C C   . ALA A 75  ? 0.18370 0.23580 0.15990 0.00670  -0.02540 -0.06140 79  ALA A C   
818  O O   . ALA A 75  ? 0.20480 0.25670 0.15780 0.00830  -0.01710 -0.04750 79  ALA A O   
819  C CB  . ALA A 75  ? 0.16640 0.25280 0.17520 -0.00750 0.00070  -0.05730 79  ALA A CB  
825  N N   . VAL A 76  ? 0.17570 0.23860 0.16280 0.00800  -0.01450 -0.04010 80  VAL A N   
826  C CA  . VAL A 76  ? 0.21650 0.24280 0.16190 0.00560  -0.02590 -0.04250 80  VAL A CA  
827  C C   . VAL A 76  ? 0.19670 0.24100 0.16230 0.01620  -0.02740 -0.05140 80  VAL A C   
828  O O   . VAL A 76  ? 0.20720 0.24800 0.17160 0.04330  -0.03380 -0.05840 80  VAL A O   
829  C CB  . VAL A 76  ? 0.23800 0.24820 0.17060 -0.00500 -0.04530 -0.04030 80  VAL A CB  
830  C CG1 . VAL A 76  ? 0.25190 0.26250 0.19700 -0.00470 -0.07190 -0.03670 80  VAL A CG1 
831  C CG2 . VAL A 76  ? 0.24440 0.25140 0.17060 -0.01670 -0.03570 -0.02320 80  VAL A CG2 
841  N N   . LEU A 77  ? 0.21850 0.23350 0.15390 0.03030  -0.01770 -0.03870 81  LEU A N   
842  C CA  . LEU A 77  ? 0.19780 0.24540 0.19180 0.02180  -0.02240 -0.03660 81  LEU A CA  
843  C C   . LEU A 77  ? 0.20460 0.23400 0.20550 0.00410  -0.03050 -0.04020 81  LEU A C   
844  O O   . LEU A 77  ? 0.21930 0.22830 0.21460 -0.00170 -0.03650 -0.03550 81  LEU A O   
845  C CB  . LEU A 77  ? 0.17860 0.25470 0.18740 0.02270  -0.03280 -0.02660 81  LEU A CB  
846  C CG  . LEU A 77  ? 0.15710 0.25390 0.17310 0.00140  -0.02790 -0.02420 81  LEU A CG  
847  C CD1 . LEU A 77  ? 0.16900 0.25450 0.16760 -0.01050 -0.01240 -0.02950 81  LEU A CD1 
848  C CD2 . LEU A 77  ? 0.17490 0.25820 0.19290 -0.01650 -0.02750 -0.02180 81  LEU A CD2 
860  N N   . ALA A 78  ? 0.22990 0.22840 0.20330 0.01460  -0.04090 -0.06270 82  ALA A N   
861  C CA  . ALA A 78  ? 0.22830 0.22990 0.21400 0.02950  -0.03960 -0.06850 82  ALA A CA  
862  C C   . ALA A 78  ? 0.24530 0.24230 0.22720 0.03610  -0.04390 -0.07910 82  ALA A C   
863  O O   . ALA A 78  ? 0.26600 0.24220 0.22160 0.04340  -0.06060 -0.06570 82  ALA A O   
864  C CB  . ALA A 78  ? 0.23440 0.23840 0.23740 0.02260  -0.05050 -0.04590 82  ALA A CB  
870  N N   . ARG A 79  ? 0.25980 0.26170 0.22420 0.05190  -0.02930 -0.09570 83  ARG A N   
871  C CA  . ARG A 79  ? 0.28520 0.29370 0.23570 0.04360  -0.01700 -0.09260 83  ARG A CA  
872  C C   . ARG A 79  ? 0.29700 0.30060 0.23430 0.05370  -0.04380 -0.08810 83  ARG A C   
873  O O   . ARG A 79  ? 0.31180 0.30940 0.24810 0.07080  -0.04780 -0.08630 83  ARG A O   
874  C CB  . ARG A 79  ? 0.32830 0.32490 0.24050 0.03670  0.00300  -0.07990 83  ARG A CB  
875  C CG  . ARG A 79  ? 0.38010 0.35910 0.28380 0.00750  -0.01600 -0.05960 83  ARG A CG  
876  C CD  . ARG A 79  ? 0.41690 0.39500 0.37420 -0.01150 -0.01990 -0.03240 83  ARG A CD  
877  N NE  . ARG A 79  ? 0.44730 0.42420 0.42210 -0.01660 -0.00730 -0.00200 83  ARG A NE  
878  C CZ  . ARG A 79  ? 0.46530 0.44520 0.45790 -0.00840 0.01260  0.02330  83  ARG A CZ  
879  N NH1 . ARG A 79  ? 0.48250 0.45850 0.47050 0.00060  0.02160  0.01730  83  ARG A NH1 
880  N NH2 . ARG A 79  ? 0.45350 0.44940 0.46100 -0.00670 0.01840  0.03530  83  ARG A NH2 
894  N N   . SER A 80  ? 0.28170 0.28680 0.21080 0.05300  -0.05330 -0.08430 84  SER A N   
895  C CA  . SER A 80  ? 0.28900 0.28460 0.23000 0.03730  -0.07150 -0.07400 84  SER A CA  
896  C C   . SER A 80  ? 0.32370 0.29240 0.25940 0.02670  -0.09080 -0.06550 84  SER A C   
897  O O   . SER A 80  ? 0.36430 0.29520 0.26670 0.01880  -0.10670 -0.06380 84  SER A O   
898  C CB  . SER A 80  ? 0.27960 0.29140 0.24910 0.03300  -0.07540 -0.05610 84  SER A CB  
899  O OG  . SER A 80  ? 0.29590 0.28650 0.27070 0.01710  -0.07520 -0.06250 84  SER A OG  
905  N N   . GLN A 81  ? 0.34430 0.30130 0.27290 0.02530  -0.09030 -0.05610 85  GLN A N   
906  C CA  . GLN A 81  ? 0.36570 0.32020 0.29600 0.03360  -0.08710 -0.06430 85  GLN A CA  
907  C C   . GLN A 81  ? 0.41150 0.34540 0.32000 0.05550  -0.09590 -0.05130 85  GLN A C   
908  O O   . GLN A 81  ? 0.44270 0.34350 0.34210 0.05400  -0.10790 -0.04890 85  GLN A O   
909  C CB  . GLN A 81  ? 0.36030 0.31900 0.28320 0.03160  -0.06850 -0.06480 85  GLN A CB  
910  C CG  . GLN A 81  ? 0.37140 0.32480 0.29090 0.02140  -0.04810 -0.06620 85  GLN A CG  
911  C CD  . GLN A 81  ? 0.36980 0.33660 0.30690 0.03690  -0.04300 -0.05490 85  GLN A CD  
912  O OE1 . GLN A 81  ? 0.37040 0.33430 0.31570 0.02710  -0.02080 -0.05320 85  GLN A OE1 
913  N NE2 . GLN A 81  ? 0.39250 0.36050 0.31390 0.05140  -0.05370 -0.05050 85  GLN A NE2 
922  N N   . GLN A 82  ? 0.43200 0.37850 0.32920 0.08190  -0.07120 -0.04450 86  GLN A N   
923  C CA  A GLN A 82  ? 0.45440 0.40000 0.35520 0.08490  -0.05170 -0.04470 86  GLN A CA  
924  C CA  B GLN A 82  ? 0.44840 0.39720 0.35590 0.08640  -0.05120 -0.04020 86  GLN A CA  
925  C C   . GLN A 82  ? 0.46550 0.39710 0.34440 0.09460  -0.05680 -0.05010 86  GLN A C   
926  O O   . GLN A 82  ? 0.48360 0.39610 0.33410 0.10610  -0.06240 -0.06310 86  GLN A O   
927  C CB  A GLN A 82  ? 0.46060 0.42010 0.38880 0.07770  -0.03350 -0.04110 86  GLN A CB  
928  C CB  B GLN A 82  ? 0.44350 0.41150 0.39080 0.08260  -0.03180 -0.02730 86  GLN A CB  
929  C CG  A GLN A 82  ? 0.47450 0.43740 0.42640 0.06480  -0.01670 -0.03520 86  GLN A CG  
930  C CG  B GLN A 82  ? 0.44610 0.42260 0.42840 0.07450  -0.01540 -0.01230 86  GLN A CG  
931  C CD  A GLN A 82  ? 0.48330 0.45110 0.45690 0.05230  -0.00020 -0.03040 86  GLN A CD  
932  C CD  B GLN A 82  ? 0.44960 0.43320 0.45440 0.07110  -0.00200 -0.00390 86  GLN A CD  
933  O OE1 A GLN A 82  ? 0.48420 0.45680 0.47320 0.04510  0.01010  -0.02920 86  GLN A OE1 
934  O OE1 B GLN A 82  ? 0.45590 0.43870 0.47480 0.07620  0.00990  -0.00170 86  GLN A OE1 
935  N NE2 A GLN A 82  ? 0.49070 0.46000 0.46890 0.04750  -0.00150 -0.02870 86  GLN A NE2 
936  N NE2 B GLN A 82  ? 0.44110 0.43440 0.45790 0.06630  -0.00640 -0.00490 86  GLN A NE2 
953  N N   . GLN A 83  ? 0.46150 0.38650 0.31170 0.09080  -0.06830 -0.04650 87  GLN A N   
954  C CA  A GLN A 83  ? 0.45960 0.38070 0.31030 0.08030  -0.06490 -0.04110 87  GLN A CA  
955  C CA  B GLN A 83  ? 0.45550 0.37880 0.31280 0.07940  -0.06690 -0.04090 87  GLN A CA  
956  C C   . GLN A 83  ? 0.45870 0.36860 0.29780 0.07550  -0.08690 -0.04490 87  GLN A C   
957  O O   . GLN A 83  ? 0.44710 0.34880 0.26610 0.09250  -0.10990 -0.06450 87  GLN A O   
958  C CB  A GLN A 83  ? 0.45870 0.38810 0.32060 0.07650  -0.04070 -0.04050 87  GLN A CB  
959  C CB  B GLN A 83  ? 0.44790 0.38270 0.32660 0.07520  -0.04570 -0.03950 87  GLN A CB  
960  C CG  A GLN A 83  ? 0.45250 0.39370 0.32630 0.07150  -0.01870 -0.03850 87  GLN A CG  
961  C CG  B GLN A 83  ? 0.43780 0.38570 0.33670 0.07220  -0.02500 -0.03990 87  GLN A CG  
962  C CD  A GLN A 83  ? 0.44890 0.40340 0.34130 0.06730  -0.01160 -0.03820 87  GLN A CD  
963  C CD  B GLN A 83  ? 0.42810 0.38990 0.35000 0.07080  -0.01030 -0.03730 87  GLN A CD  
964  O OE1 A GLN A 83  ? 0.46000 0.41280 0.36240 0.06560  -0.01280 -0.03400 87  GLN A OE1 
965  O OE1 B GLN A 83  ? 0.42990 0.39730 0.35730 0.06990  -0.00600 -0.03590 87  GLN A OE1 
966  N NE2 A GLN A 83  ? 0.44190 0.40180 0.32760 0.07340  -0.01510 -0.03420 87  GLN A NE2 
967  N NE2 B GLN A 83  ? 0.42480 0.38910 0.36330 0.06690  -0.00610 -0.04150 87  GLN A NE2 
984  N N   . ALA A 84  ? 0.46810 0.35940 0.32470 0.06240  -0.08540 -0.03180 88  ALA A N   
985  C CA  . ALA A 84  ? 0.45680 0.35650 0.33420 0.05230  -0.09260 -0.02130 88  ALA A CA  
986  C C   . ALA A 84  ? 0.45690 0.35600 0.35080 0.05520  -0.10020 -0.02200 88  ALA A C   
987  O O   . ALA A 84  ? 0.45260 0.36790 0.37870 0.05690  -0.11060 -0.01070 88  ALA A O   
988  C CB  . ALA A 84  ? 0.45850 0.36230 0.34080 0.04190  -0.08780 -0.01100 88  ALA A CB  
994  N N   . ASP A 85  ? 0.46290 0.33960 0.32460 0.05370  -0.11710 -0.02660 89  ASP A N   
995  C CA  . ASP A 85  ? 0.47090 0.33450 0.31840 0.05130  -0.12560 -0.04420 89  ASP A CA  
996  C C   . ASP A 85  ? 0.44210 0.32200 0.28990 0.03610  -0.12710 -0.04470 89  ASP A C   
997  O O   . ASP A 85  ? 0.46430 0.32920 0.30420 0.03690  -0.11310 -0.05300 89  ASP A O   
998  C CB  . ASP A 85  ? 0.51290 0.35760 0.36370 0.06450  -0.09340 -0.03610 89  ASP A CB  
999  C CG  . ASP A 85  ? 0.54840 0.37660 0.40400 0.07270  -0.07850 -0.03990 89  ASP A CG  
1000 O OD1 . ASP A 85  ? 0.55800 0.37930 0.42850 0.07120  -0.06690 -0.04240 89  ASP A OD1 
1001 O OD2 . ASP A 85  ? 0.57790 0.38810 0.43160 0.08100  -0.07180 -0.05050 89  ASP A OD2 
1006 N N   . LEU A 86  ? 0.39450 0.30890 0.24570 0.03650  -0.11980 -0.04690 90  LEU A N   
1007 C CA  . LEU A 86  ? 0.33710 0.29960 0.23390 0.02940  -0.09680 -0.03370 90  LEU A CA  
1008 C C   . LEU A 86  ? 0.29560 0.29290 0.21660 0.00780  -0.09570 -0.03360 90  LEU A C   
1009 O O   . LEU A 86  ? 0.28620 0.28480 0.22150 0.00400  -0.07030 -0.04420 90  LEU A O   
1010 C CB  . LEU A 86  ? 0.31410 0.30470 0.24440 0.03100  -0.06990 -0.02950 90  LEU A CB  
1011 C CG  . LEU A 86  ? 0.28220 0.30890 0.23790 0.03930  -0.06510 -0.02070 90  LEU A CG  
1012 C CD1 . LEU A 86  ? 0.28630 0.31350 0.24630 0.04090  -0.03760 -0.03130 90  LEU A CD1 
1013 C CD2 . LEU A 86  ? 0.27940 0.30790 0.23760 0.04230  -0.05450 -0.00210 90  LEU A CD2 
1025 N N   . LEU A 87  ? 0.29560 0.29420 0.23820 0.00030  -0.09310 -0.02810 91  LEU A N   
1026 C CA  . LEU A 87  ? 0.27730 0.28030 0.23750 -0.01500 -0.08440 -0.01010 91  LEU A CA  
1027 C C   . LEU A 87  ? 0.27350 0.28230 0.23090 -0.01360 -0.07070 -0.00700 91  LEU A C   
1028 O O   . LEU A 87  ? 0.25290 0.26810 0.21120 -0.01740 -0.06810 -0.01700 91  LEU A O   
1029 C CB  . LEU A 87  ? 0.28070 0.27780 0.23240 -0.03360 -0.10120 0.00320  91  LEU A CB  
1030 C CG  . LEU A 87  ? 0.27430 0.28790 0.24210 -0.06060 -0.10230 0.01880  91  LEU A CG  
1031 C CD1 . LEU A 87  ? 0.31280 0.30540 0.27060 -0.07650 -0.08680 0.03200  91  LEU A CD1 
1032 C CD2 . LEU A 87  ? 0.25050 0.29490 0.25550 -0.07010 -0.10190 -0.01210 91  LEU A CD2 
1044 N N   . ASP A 88  ? 0.28660 0.29970 0.24360 -0.00930 -0.07690 0.00470  92  ASP A N   
1045 C CA  . ASP A 88  ? 0.30470 0.30960 0.24520 -0.02070 -0.08360 0.01020  92  ASP A CA  
1046 C C   . ASP A 88  ? 0.28660 0.29900 0.21380 -0.01210 -0.06410 -0.01400 92  ASP A C   
1047 O O   . ASP A 88  ? 0.28830 0.30740 0.21520 -0.00050 -0.08000 -0.01990 92  ASP A O   
1048 C CB  . ASP A 88  ? 0.34410 0.32960 0.29210 -0.03280 -0.09980 0.03040  92  ASP A CB  
1049 C CG  . ASP A 88  ? 0.38300 0.35470 0.36020 -0.01890 -0.08620 0.03620  92  ASP A CG  
1050 O OD1 . ASP A 88  ? 0.38010 0.36330 0.34440 0.00800  -0.06890 0.05280  92  ASP A OD1 
1051 O OD2 . ASP A 88  ? 0.41260 0.37740 0.43080 -0.02870 -0.07390 0.04420  92  ASP A OD2 
1056 N N   . THR A 89  ? 0.26780 0.27930 0.20310 -0.00180 -0.04920 -0.02530 93  THR A N   
1057 C CA  . THR A 89  ? 0.27180 0.27930 0.19400 0.01440  -0.03260 -0.02900 93  THR A CA  
1058 C C   . THR A 89  ? 0.25280 0.27000 0.18420 0.00920  -0.00340 -0.03300 93  THR A C   
1059 O O   . THR A 89  ? 0.23150 0.28590 0.18610 -0.00300 -0.00800 -0.03390 93  THR A O   
1060 C CB  . THR A 89  ? 0.29440 0.28300 0.21680 0.03290  -0.02070 -0.02290 93  THR A CB  
1061 O OG1 . THR A 89  ? 0.34780 0.29420 0.24190 0.04810  -0.02140 -0.01990 93  THR A OG1 
1062 C CG2 . THR A 89  ? 0.29360 0.28250 0.24290 0.02740  -0.00570 -0.03830 93  THR A CG2 
1070 N N   A PRO A 90  ? 0.27140 0.26650 0.16840 0.00910  -0.00250 -0.01600 94  PRO A N   
1071 N N   B PRO A 90  ? 0.27730 0.26310 0.17530 0.00880  -0.00580 -0.03740 94  PRO A N   
1072 C CA  A PRO A 90  ? 0.26970 0.26600 0.16970 0.01900  -0.00810 -0.00910 94  PRO A CA  
1073 C CA  B PRO A 90  ? 0.27510 0.26410 0.17010 0.01290  0.00200  -0.03410 94  PRO A CA  
1074 C C   A PRO A 90  ? 0.26450 0.26340 0.16830 0.02290  0.00490  -0.00440 94  PRO A C   
1075 C C   B PRO A 90  ? 0.26750 0.26960 0.15230 0.01510  0.03270  -0.02160 94  PRO A C   
1076 O O   A PRO A 90  ? 0.27480 0.25310 0.18200 0.03870  0.00590  0.00660  94  PRO A O   
1077 O O   B PRO A 90  ? 0.27580 0.27510 0.12850 0.01680  0.06730  -0.01750 94  PRO A O   
1078 C CB  A PRO A 90  ? 0.27090 0.27140 0.16130 0.02300  -0.01350 -0.00730 94  PRO A CB  
1079 C CB  B PRO A 90  ? 0.28010 0.26270 0.17030 0.01450  -0.00760 -0.04100 94  PRO A CB  
1080 C CG  A PRO A 90  ? 0.26190 0.27030 0.14410 0.01170  -0.02160 0.00230  94  PRO A CG  
1081 C CG  B PRO A 90  ? 0.28320 0.25530 0.17560 0.01000  -0.02810 -0.04440 94  PRO A CG  
1082 C CD  A PRO A 90  ? 0.26770 0.26770 0.14920 0.00930  -0.00420 -0.01000 94  PRO A CD  
1083 C CD  B PRO A 90  ? 0.28240 0.25810 0.17330 0.00980  -0.01740 -0.04750 94  PRO A CD  
1098 N N   . ILE A 91  ? 0.26500 0.27260 0.15970 0.00750  0.01540  -0.00350 95  ILE A N   
1099 C CA  . ILE A 91  ? 0.25580 0.29460 0.17810 0.00310  0.02500  0.00550  95  ILE A CA  
1100 C C   . ILE A 91  ? 0.23890 0.31070 0.16720 0.01310  0.03210  0.01250  95  ILE A C   
1101 O O   . ILE A 91  ? 0.21410 0.29940 0.16790 0.02250  0.02000  0.02840  95  ILE A O   
1102 C CB  . ILE A 91  ? 0.27520 0.30680 0.22620 0.00270  0.00120  -0.00050 95  ILE A CB  
1103 C CG1 . ILE A 91  ? 0.30730 0.31690 0.26790 0.00870  -0.01110 -0.00480 95  ILE A CG1 
1104 C CG2 . ILE A 91  ? 0.29010 0.31170 0.23810 0.00420  -0.02450 -0.00060 95  ILE A CG2 
1105 C CD1 . ILE A 91  ? 0.33150 0.33310 0.31500 0.01610  -0.00020 0.01540  95  ILE A CD1 
1118 N N   . ARG A 92  ? 0.24640 0.33240 0.16280 0.00430  0.04530  0.01290  96  ARG A N   
1119 C CA  . ARG A 92  ? 0.23670 0.34070 0.16560 -0.00160 0.02210  0.01540  96  ARG A CA  
1120 C C   . ARG A 92  ? 0.20520 0.34120 0.18540 0.01680  0.01840  0.01370  96  ARG A C   
1121 O O   . ARG A 92  ? 0.21490 0.35500 0.23950 0.02470  0.02400  0.02590  96  ARG A O   
1122 C CB  . ARG A 92  ? 0.29130 0.34520 0.15230 -0.03400 0.02460  0.02030  96  ARG A CB  
1123 C CG  . ARG A 92  ? 0.33230 0.35280 0.15180 -0.05410 0.00990  -0.00050 96  ARG A CG  
1124 C CD  . ARG A 92  ? 0.35880 0.37470 0.19380 -0.06310 0.00520  0.01320  96  ARG A CD  
1125 N NE  . ARG A 92  ? 0.35400 0.38710 0.18170 -0.08310 -0.00810 0.03390  96  ARG A NE  
1126 C CZ  . ARG A 92  ? 0.33770 0.40370 0.16970 -0.09370 -0.01740 0.02310  96  ARG A CZ  
1127 N NH1 . ARG A 92  ? 0.34830 0.41630 0.17600 -0.08320 -0.03850 0.01780  96  ARG A NH1 
1128 N NH2 . ARG A 92  ? 0.34260 0.41360 0.19100 -0.09190 0.01080  0.03070  96  ARG A NH2 
1142 N N   . TYR A 93  ? 0.18320 0.34320 0.13690 0.01460  0.01160  0.01050  97  TYR A N   
1143 C CA  . TYR A 93  ? 0.17690 0.33680 0.16460 0.00070  0.02530  0.01880  97  TYR A CA  
1144 C C   . TYR A 93  ? 0.19270 0.36630 0.17420 -0.01940 0.01760  0.01630  97  TYR A C   
1145 O O   . TYR A 93  ? 0.19130 0.37460 0.16320 -0.01480 0.00850  0.03140  97  TYR A O   
1146 C CB  . TYR A 93  ? 0.16870 0.31380 0.15980 -0.00770 0.00700  0.02050  97  TYR A CB  
1147 C CG  . TYR A 93  ? 0.15600 0.29810 0.12350 -0.00210 -0.00550 0.01030  97  TYR A CG  
1148 C CD1 . TYR A 93  ? 0.17800 0.30000 0.11230 0.00950  -0.00580 0.01840  97  TYR A CD1 
1149 C CD2 . TYR A 93  ? 0.15700 0.29480 0.12530 -0.00330 -0.00130 0.01410  97  TYR A CD2 
1150 C CE1 . TYR A 93  ? 0.16070 0.29650 0.11090 0.01060  -0.00900 0.00580  97  TYR A CE1 
1151 C CE2 . TYR A 93  ? 0.14820 0.29150 0.11740 -0.00710 -0.00980 0.00020  97  TYR A CE2 
1152 C CZ  . TYR A 93  ? 0.14960 0.30200 0.11230 -0.01620 0.00240  0.00230  97  TYR A CZ  
1153 O OH  . TYR A 93  ? 0.16290 0.32050 0.12080 -0.01970 -0.00750 0.00350  97  TYR A OH  
1163 N N   . GLY A 94  ? 0.22070 0.37590 0.17510 -0.04050 0.01960  0.03970  98  GLY A N   
1164 C CA  . GLY A 94  ? 0.24000 0.38330 0.18060 -0.03270 0.01290  0.04120  98  GLY A CA  
1165 C C   . GLY A 94  ? 0.23590 0.39610 0.18060 -0.06080 0.00960  0.03660  98  GLY A C   
1166 O O   . GLY A 94  ? 0.22770 0.39610 0.16420 -0.06360 0.01370  0.05210  98  GLY A O   
1170 N N   . LYS A 95  ? 0.25470 0.40220 0.18880 -0.08140 0.03030  0.04080  99  LYS A N   
1171 C CA  . LYS A 95  ? 0.32250 0.41220 0.23640 -0.07570 0.02690  0.04750  99  LYS A CA  
1172 C C   . LYS A 95  ? 0.34520 0.41750 0.22730 -0.10650 0.01490  0.03960  99  LYS A C   
1173 O O   . LYS A 95  ? 0.38410 0.41840 0.22680 -0.11330 -0.00320 0.03800  99  LYS A O   
1174 C CB  . LYS A 95  ? 0.39290 0.42780 0.29970 -0.04380 0.01690  0.04690  99  LYS A CB  
1175 C CG  . LYS A 95  ? 0.45670 0.45370 0.38540 -0.01370 -0.00190 0.04970  99  LYS A CG  
1176 C CD  . LYS A 95  ? 0.50370 0.47480 0.45760 0.00840  0.00100  0.05260  99  LYS A CD  
1177 C CE  . LYS A 95  ? 0.54160 0.48930 0.51450 0.01630  -0.00150 0.05460  99  LYS A CE  
1178 N NZ  . LYS A 95  ? 0.56110 0.49670 0.54900 0.01970  -0.00090 0.05020  99  LYS A NZ  
1192 N N   . ASN A 96  ? 0.31480 0.43050 0.22990 -0.14030 -0.00220 0.04930  100 ASN A N   
1193 C CA  . ASN A 96  ? 0.34620 0.44870 0.28210 -0.14840 -0.01180 0.06010  100 ASN A CA  
1194 C C   . ASN A 96  ? 0.34860 0.44570 0.26250 -0.15720 -0.04080 0.05260  100 ASN A C   
1195 O O   . ASN A 96  ? 0.36200 0.45820 0.28110 -0.17880 -0.07090 0.02870  100 ASN A O   
1196 C CB  . ASN A 96  ? 0.36470 0.47550 0.33610 -0.13850 -0.00900 0.05900  100 ASN A CB  
1197 C CG  . ASN A 96  ? 0.39440 0.50420 0.38560 -0.12630 -0.00900 0.05970  100 ASN A CG  
1198 O OD1 . ASN A 96  ? 0.40860 0.51550 0.40030 -0.12030 -0.01790 0.07770  100 ASN A OD1 
1199 N ND2 . ASN A 96  ? 0.42890 0.52380 0.43000 -0.11950 -0.00670 0.04030  100 ASN A ND2 
1206 N N   . ALA A 97  ? 0.32770 0.42530 0.21510 -0.14200 -0.03710 0.06500  101 ALA A N   
1207 C CA  . ALA A 97  ? 0.32160 0.41620 0.22960 -0.12700 -0.03790 0.06640  101 ALA A CA  
1208 C C   . ALA A 97  ? 0.29920 0.40370 0.21240 -0.12710 -0.01770 0.07210  101 ALA A C   
1209 O O   . ALA A 97  ? 0.28960 0.42500 0.19500 -0.11210 -0.02670 0.06360  101 ALA A O   
1210 C CB  . ALA A 97  ? 0.32180 0.41550 0.23090 -0.10550 -0.03790 0.06220  101 ALA A CB  
1216 N N   . LEU A 98  ? 0.34120 0.38570 0.22000 -0.12380 -0.01280 0.07020  102 LEU A N   
1217 C CA  . LEU A 98  ? 0.36410 0.37250 0.23570 -0.12330 -0.02280 0.05720  102 LEU A CA  
1218 C C   . LEU A 98  ? 0.40470 0.37160 0.28100 -0.13290 -0.03330 0.05470  102 LEU A C   
1219 O O   . LEU A 98  ? 0.45240 0.37670 0.31590 -0.12500 -0.10330 0.03770  102 LEU A O   
1220 C CB  . LEU A 98  ? 0.35930 0.36720 0.23000 -0.09920 -0.01210 0.05680  102 LEU A CB  
1221 C CG  . LEU A 98  ? 0.33290 0.36370 0.22980 -0.08900 -0.05370 0.04060  102 LEU A CG  
1222 C CD1 . LEU A 98  ? 0.35120 0.37510 0.23920 -0.08460 -0.06020 0.04840  102 LEU A CD1 
1223 C CD2 . LEU A 98  ? 0.29050 0.35200 0.23640 -0.09020 -0.05980 0.03740  102 LEU A CD2 
1235 N N   . VAL A 99  ? 0.38780 0.37200 0.28000 -0.12990 -0.02490 0.03330  103 VAL A N   
1236 C CA  . VAL A 99  ? 0.39200 0.37310 0.28650 -0.11650 -0.01220 0.03420  103 VAL A CA  
1237 C C   . VAL A 99  ? 0.38440 0.36070 0.25330 -0.11250 -0.02250 0.03810  103 VAL A C   
1238 O O   . VAL A 99  ? 0.37170 0.36310 0.23300 -0.10700 -0.01280 0.04510  103 VAL A O   
1239 C CB  . VAL A 99  ? 0.39740 0.38350 0.29130 -0.10060 -0.01700 0.04490  103 VAL A CB  
1240 C CG1 . VAL A 99  ? 0.39710 0.39040 0.31100 -0.09580 0.00470  0.04170  103 VAL A CG1 
1241 C CG2 . VAL A 99  ? 0.38640 0.37560 0.26800 -0.11270 -0.03000 0.06870  103 VAL A CG2 
1251 N N   . PRO A 100 ? 0.39260 0.34620 0.23830 -0.10190 -0.04390 0.04380  104 PRO A N   
1252 C CA  . PRO A 100 ? 0.37610 0.33240 0.23940 -0.08440 -0.05600 0.05170  104 PRO A CA  
1253 C C   . PRO A 100 ? 0.32670 0.32120 0.21290 -0.05440 -0.06720 0.05040  104 PRO A C   
1254 O O   . PRO A 100 ? 0.33040 0.34230 0.21240 -0.02210 -0.04600 0.07920  104 PRO A O   
1255 C CB  . PRO A 100 ? 0.41020 0.34110 0.25760 -0.09500 -0.05070 0.04610  104 PRO A CB  
1256 C CG  . PRO A 100 ? 0.41810 0.34580 0.27920 -0.10180 -0.04250 0.04960  104 PRO A CG  
1257 C CD  . PRO A 100 ? 0.41120 0.35000 0.26100 -0.10340 -0.04110 0.04570  104 PRO A CD  
1265 N N   . TRP A 101 ? 0.30520 0.30670 0.19990 -0.03480 -0.08670 0.00310  105 TRP A N   
1266 C CA  A TRP A 101 ? 0.26560 0.29240 0.18660 -0.02850 -0.08920 -0.00950 105 TRP A CA  
1267 C CA  B TRP A 101 ? 0.27550 0.29700 0.18440 -0.02430 -0.08980 -0.01250 105 TRP A CA  
1268 C C   . TRP A 101 ? 0.25130 0.28700 0.18290 -0.02650 -0.06920 -0.01660 105 TRP A C   
1269 O O   . TRP A 101 ? 0.24330 0.28760 0.16990 0.00370  -0.06160 -0.01800 105 TRP A O   
1270 C CB  A TRP A 101 ? 0.25070 0.28720 0.19390 -0.02170 -0.07930 -0.00320 105 TRP A CB  
1271 C CB  B TRP A 101 ? 0.28330 0.30210 0.19450 -0.00650 -0.07160 -0.00730 105 TRP A CB  
1272 C CG  A TRP A 101 ? 0.23130 0.27880 0.20800 -0.02290 -0.08200 -0.01040 105 TRP A CG  
1273 C CG  B TRP A 101 ? 0.29070 0.30420 0.22040 0.00510  -0.06380 -0.01660 105 TRP A CG  
1274 C CD1 A TRP A 101 ? 0.22870 0.27850 0.20290 -0.02130 -0.07430 -0.00450 105 TRP A CD1 
1275 C CD1 B TRP A 101 ? 0.29970 0.30430 0.20840 0.00430  -0.05460 -0.01510 105 TRP A CD1 
1276 C CD2 A TRP A 101 ? 0.24150 0.27570 0.22790 -0.02590 -0.06160 -0.01040 105 TRP A CD2 
1277 C CD2 B TRP A 101 ? 0.31270 0.30890 0.24470 0.01200  -0.04410 -0.02040 105 TRP A CD2 
1278 N NE1 A TRP A 101 ? 0.24560 0.27750 0.22400 -0.02430 -0.06830 -0.00080 105 TRP A NE1 
1279 N NE1 B TRP A 101 ? 0.31260 0.30850 0.23500 0.00260  -0.05640 -0.01510 105 TRP A NE1 
1280 C CE2 A TRP A 101 ? 0.24890 0.27530 0.23490 -0.02300 -0.05480 -0.01030 105 TRP A CE2 
1281 C CE2 B TRP A 101 ? 0.31650 0.30930 0.24520 0.01010  -0.04500 -0.02360 105 TRP A CE2 
1282 C CE3 A TRP A 101 ? 0.24820 0.27520 0.24750 -0.02050 -0.03840 -0.00900 105 TRP A CE3 
1283 C CE3 B TRP A 101 ? 0.31950 0.31290 0.25900 0.02110  -0.02880 -0.01220 105 TRP A CE3 
1284 C CZ2 A TRP A 101 ? 0.25690 0.27290 0.23750 -0.02860 -0.03730 -0.00860 105 TRP A CZ2 
1285 C CZ2 B TRP A 101 ? 0.32260 0.30820 0.25750 0.02230  -0.03640 -0.02340 105 TRP A CZ2 
1286 C CZ3 A TRP A 101 ? 0.25560 0.27610 0.25030 -0.02160 -0.02590 0.00170  105 TRP A CZ3 
1287 C CZ3 B TRP A 101 ? 0.32380 0.31350 0.27800 0.02570  -0.02260 -0.00990 105 TRP A CZ3 
1288 C CH2 A TRP A 101 ? 0.25860 0.27520 0.25260 -0.02850 -0.03150 -0.00780 105 TRP A CH2 
1289 C CH2 B TRP A 101 ? 0.32510 0.31280 0.26970 0.03020  -0.02610 -0.01110 105 TRP A CH2 
1310 N N   . SER A 102 ? 0.21570 0.27040 0.16970 -0.04380 -0.06230 -0.00970 106 SER A N   
1311 C CA  . SER A 102 ? 0.19470 0.28090 0.16830 -0.01760 -0.05860 -0.00740 106 SER A CA  
1312 C C   . SER A 102 ? 0.19530 0.28290 0.17270 0.00390  -0.05130 -0.00570 106 SER A C   
1313 O O   . SER A 102 ? 0.21460 0.26700 0.15390 -0.00640 -0.04440 -0.00100 106 SER A O   
1314 C CB  . SER A 102 ? 0.20000 0.28430 0.15210 -0.01350 -0.04820 0.01020  106 SER A CB  
1315 O OG  . SER A 102 ? 0.21080 0.28850 0.16850 -0.03850 -0.02730 0.01320  106 SER A OG  
1321 N N   . PRO A 103 ? 0.18860 0.29160 0.15890 0.00540  -0.04700 0.00180  107 PRO A N   
1322 C CA  . PRO A 103 ? 0.20880 0.29090 0.18110 -0.00490 -0.04070 -0.01280 107 PRO A CA  
1323 C C   . PRO A 103 ? 0.19560 0.27700 0.18260 -0.01570 -0.03910 -0.00940 107 PRO A C   
1324 O O   . PRO A 103 ? 0.21510 0.28500 0.23870 -0.01930 -0.06640 -0.02630 107 PRO A O   
1325 C CB  . PRO A 103 ? 0.22860 0.29920 0.20040 -0.00660 -0.00930 -0.01850 107 PRO A CB  
1326 C CG  . PRO A 103 ? 0.23300 0.30240 0.19200 0.00750  -0.01040 -0.01020 107 PRO A CG  
1327 C CD  . PRO A 103 ? 0.22320 0.29990 0.15950 -0.00880 -0.01350 -0.00860 107 PRO A CD  
1335 N N   . ILE A 104 ? 0.17670 0.26760 0.14920 -0.01270 -0.02950 0.00480  108 ILE A N   
1336 C CA  . ILE A 104 ? 0.15380 0.26580 0.13180 -0.00110 -0.02600 -0.00500 108 ILE A CA  
1337 C C   . ILE A 104 ? 0.13760 0.25720 0.13630 -0.00410 -0.01700 -0.00420 108 ILE A C   
1338 O O   . ILE A 104 ? 0.15740 0.25310 0.13910 -0.00990 -0.04150 0.01520  108 ILE A O   
1339 C CB  . ILE A 104 ? 0.16120 0.27960 0.13430 -0.00120 -0.03100 0.00070  108 ILE A CB  
1340 C CG1 . ILE A 104 ? 0.16410 0.30880 0.13800 -0.00590 -0.00050 0.02340  108 ILE A CG1 
1341 C CG2 . ILE A 104 ? 0.18420 0.27270 0.12610 0.00770  -0.01140 -0.00850 108 ILE A CG2 
1342 C CD1 . ILE A 104 ? 0.18320 0.33490 0.15770 0.00570  0.02640  0.02260  108 ILE A CD1 
1354 N N   A SER A 105 ? 0.14530 0.27030 0.14290 -0.00110 -0.02760 0.00180  109 SER A N   
1355 N N   B SER A 105 ? 0.13880 0.25220 0.13710 -0.01200 -0.00910 -0.00770 109 SER A N   
1356 C CA  A SER A 105 ? 0.16570 0.27640 0.15590 0.00170  -0.03940 -0.00550 109 SER A CA  
1357 C CA  B SER A 105 ? 0.14510 0.24770 0.14110 -0.02000 -0.00430 -0.01550 109 SER A CA  
1358 C C   A SER A 105 ? 0.15240 0.28820 0.14180 -0.01520 -0.03330 -0.00370 109 SER A C   
1359 C C   B SER A 105 ? 0.13650 0.26250 0.14170 -0.03040 -0.02480 -0.01280 109 SER A C   
1360 O O   A SER A 105 ? 0.14490 0.31420 0.12080 -0.01920 -0.02060 0.00010  109 SER A O   
1361 O O   B SER A 105 ? 0.12250 0.26650 0.13510 -0.04040 -0.03530 -0.02580 109 SER A O   
1362 C CB  A SER A 105 ? 0.17030 0.28140 0.15370 -0.00540 -0.05020 0.00450  109 SER A CB  
1363 C CB  B SER A 105 ? 0.14290 0.23570 0.13810 -0.02790 0.02100  -0.01480 109 SER A CB  
1364 O OG  A SER A 105 ? 0.17170 0.29110 0.14510 -0.02420 -0.01610 0.02480  109 SER A OG  
1365 O OG  B SER A 105 ? 0.13530 0.23160 0.14240 -0.03050 0.04950  -0.00360 109 SER A OG  
1376 N N   . GLU A 106 ? 0.14790 0.28020 0.14630 -0.03400 -0.02300 0.00840  110 GLU A N   
1377 C CA  . GLU A 106 ? 0.17010 0.28760 0.15950 -0.01870 -0.03670 0.02320  110 GLU A CA  
1378 C C   . GLU A 106 ? 0.17100 0.28160 0.16640 -0.01120 -0.03080 0.01070  110 GLU A C   
1379 O O   . GLU A 106 ? 0.19100 0.28980 0.15520 -0.01350 -0.03080 0.03020  110 GLU A O   
1380 C CB  . GLU A 106 ? 0.21690 0.30440 0.23570 -0.01710 -0.05830 0.03280  110 GLU A CB  
1381 C CG  . GLU A 106 ? 0.27730 0.32080 0.31980 -0.01290 -0.06180 -0.00340 110 GLU A CG  
1382 C CD  . GLU A 106 ? 0.33740 0.33750 0.39660 -0.01890 -0.03820 -0.03730 110 GLU A CD  
1383 O OE1 . GLU A 106 ? 0.36250 0.34250 0.41450 -0.02740 -0.03650 -0.03520 110 GLU A OE1 
1384 O OE2 . GLU A 106 ? 0.37010 0.34760 0.43080 -0.01690 -0.02410 -0.05800 110 GLU A OE2 
1392 N N   A LYS A 107 ? 0.15240 0.27830 0.15650 -0.00120 -0.03790 0.00370  111 LYS A N   
1393 N N   B LYS A 107 ? 0.16190 0.27040 0.15800 -0.00640 -0.03230 0.00770  111 LYS A N   
1394 C CA  A LYS A 107 ? 0.15930 0.27350 0.16810 -0.00710 -0.03440 0.01300  111 LYS A CA  
1395 C CA  B LYS A 107 ? 0.16740 0.25990 0.16220 -0.01120 -0.02610 0.01420  111 LYS A CA  
1396 C C   A LYS A 107 ? 0.15710 0.26810 0.14210 -0.02030 -0.04240 0.01440  111 LYS A C   
1397 C C   B LYS A 107 ? 0.16180 0.25850 0.14340 -0.02090 -0.04430 0.01230  111 LYS A C   
1398 O O   A LYS A 107 ? 0.13710 0.28250 0.13940 -0.01810 -0.02310 0.01200  111 LYS A O   
1399 O O   B LYS A 107 ? 0.14680 0.26420 0.13620 -0.02200 -0.04210 0.01020  111 LYS A O   
1400 C CB  A LYS A 107 ? 0.16860 0.28700 0.19540 0.00230  -0.03970 0.01710  111 LYS A CB  
1401 C CB  B LYS A 107 ? 0.17830 0.26130 0.17750 -0.00310 -0.01620 0.02240  111 LYS A CB  
1402 C CG  A LYS A 107 ? 0.22070 0.30330 0.23250 0.00970  -0.01790 0.00750  111 LYS A CG  
1403 C CG  B LYS A 107 ? 0.21840 0.26640 0.19610 0.00380  0.00570  0.02420  111 LYS A CG  
1404 C CD  A LYS A 107 ? 0.25580 0.32200 0.28110 0.01870  -0.02420 -0.03160 111 LYS A CD  
1405 C CD  B LYS A 107 ? 0.24490 0.28090 0.24270 0.00900  0.00770  -0.00410 111 LYS A CD  
1406 C CE  A LYS A 107 ? 0.25710 0.33180 0.30140 0.02540  -0.04620 -0.04580 111 LYS A CE  
1407 C CE  B LYS A 107 ? 0.25650 0.28750 0.26480 0.01690  -0.00320 -0.01440 111 LYS A CE  
1408 N NZ  A LYS A 107 ? 0.25260 0.33310 0.30990 0.02620  -0.05540 -0.05250 111 LYS A NZ  
1409 N NZ  B LYS A 107 ? 0.25790 0.28920 0.27410 0.02030  -0.01040 -0.01650 111 LYS A NZ  
1436 N N   . TYR A 108 ? 0.16490 0.25700 0.15070 -0.02420 -0.05200 0.00470  112 TYR A N   
1437 C CA  . TYR A 108 ? 0.15200 0.25440 0.13570 -0.02580 -0.04170 0.00890  112 TYR A CA  
1438 C C   . TYR A 108 ? 0.15740 0.26170 0.14140 -0.02330 -0.03180 0.02500  112 TYR A C   
1439 O O   . TYR A 108 ? 0.18340 0.28150 0.12800 -0.03000 -0.02270 -0.00200 112 TYR A O   
1440 C CB  . TYR A 108 ? 0.14880 0.26360 0.14590 -0.02100 -0.02230 0.00340  112 TYR A CB  
1441 C CG  . TYR A 108 ? 0.15990 0.26550 0.13710 -0.02330 -0.01310 -0.00230 112 TYR A CG  
1442 C CD1 . TYR A 108 ? 0.15320 0.26800 0.14990 -0.04690 -0.00460 -0.02110 112 TYR A CD1 
1443 C CD2 . TYR A 108 ? 0.17490 0.27130 0.13520 -0.01340 -0.00320 -0.00640 112 TYR A CD2 
1444 C CE1 . TYR A 108 ? 0.17960 0.27470 0.14770 -0.05400 -0.02460 -0.02080 112 TYR A CE1 
1445 C CE2 . TYR A 108 ? 0.18430 0.26860 0.11980 -0.02180 -0.01300 -0.01510 112 TYR A CE2 
1446 C CZ  . TYR A 108 ? 0.16890 0.27720 0.13150 -0.03670 -0.00690 -0.01970 112 TYR A CZ  
1447 O OH  . TYR A 108 ? 0.15540 0.29820 0.14520 -0.03320 -0.00770 -0.01430 112 TYR A OH  
1458 N N   . LEU A 109 ? 0.16210 0.25880 0.16640 -0.02130 -0.01520 0.02410  113 LEU A N   
1459 C CA  . LEU A 109 ? 0.16980 0.27100 0.17750 -0.03290 -0.02080 0.02720  113 LEU A CA  
1460 C C   . LEU A 109 ? 0.16630 0.29010 0.17860 -0.02120 -0.03100 0.02440  113 LEU A C   
1461 O O   . LEU A 109 ? 0.17900 0.29730 0.16380 0.00220  -0.04130 0.00790  113 LEU A O   
1462 C CB  . LEU A 109 ? 0.16820 0.26550 0.18730 -0.04020 -0.03330 0.03510  113 LEU A CB  
1463 C CG  . LEU A 109 ? 0.18060 0.27320 0.20990 -0.06190 -0.01700 0.03110  113 LEU A CG  
1464 C CD1 . LEU A 109 ? 0.18640 0.27970 0.20890 -0.04050 -0.02640 0.01670  113 LEU A CD1 
1465 C CD2 . LEU A 109 ? 0.21300 0.28730 0.22600 -0.05220 0.01370  0.04710  113 LEU A CD2 
1477 N N   . THR A 110 ? 0.16760 0.29490 0.15280 -0.01680 -0.00780 0.03440  114 THR A N   
1478 C CA  . THR A 110 ? 0.16600 0.28460 0.16010 -0.01950 -0.00950 0.03290  114 THR A CA  
1479 C C   . THR A 110 ? 0.18390 0.27110 0.14200 -0.03010 -0.01840 0.01370  114 THR A C   
1480 O O   . THR A 110 ? 0.21720 0.28280 0.13830 -0.02140 -0.01390 0.01290  114 THR A O   
1481 C CB  . THR A 110 ? 0.17320 0.29310 0.17830 -0.03830 -0.01890 0.02360  114 THR A CB  
1482 O OG1 . THR A 110 ? 0.15410 0.30610 0.15570 -0.04370 -0.01630 0.00530  114 THR A OG1 
1483 C CG2 . THR A 110 ? 0.21030 0.29410 0.19290 -0.03960 -0.04160 0.01860  114 THR A CG2 
1491 N N   . THR A 111 ? 0.17530 0.26680 0.13940 -0.02290 -0.02480 0.02220  115 THR A N   
1492 C CA  . THR A 111 ? 0.18170 0.26930 0.13320 -0.01790 -0.01990 -0.00440 115 THR A CA  
1493 C C   . THR A 111 ? 0.18220 0.26740 0.13440 -0.01690 0.00560  0.00690  115 THR A C   
1494 O O   . THR A 111 ? 0.20200 0.27890 0.14330 -0.01350 0.00070  0.01010  115 THR A O   
1495 C CB  . THR A 111 ? 0.16920 0.26830 0.12730 -0.02870 -0.00580 0.00230  115 THR A CB  
1496 O OG1 . THR A 111 ? 0.18550 0.26280 0.12760 -0.01730 -0.00800 -0.00530 115 THR A OG1 
1497 C CG2 . THR A 111 ? 0.20930 0.26940 0.14380 -0.02430 -0.01710 0.02470  115 THR A CG2 
1505 N N   . GLY A 112 ? 0.15470 0.26460 0.12750 -0.01270 0.00650  0.01490  116 GLY A N   
1506 C CA  . GLY A 112 ? 0.17250 0.27350 0.14360 -0.02540 -0.00040 0.01020  116 GLY A CA  
1507 C C   . GLY A 112 ? 0.16360 0.27390 0.11790 -0.02160 -0.00770 -0.01000 116 GLY A C   
1508 O O   . GLY A 112 ? 0.14830 0.27410 0.13750 -0.02100 -0.01310 -0.00860 116 GLY A O   
1512 N N   . MET A 113 ? 0.14770 0.28150 0.12880 -0.00360 -0.01920 -0.00420 117 MET A N   
1513 C CA  . MET A 113 ? 0.17140 0.26760 0.11750 -0.00270 -0.00860 -0.02020 117 MET A CA  
1514 C C   . MET A 113 ? 0.19560 0.27150 0.12320 -0.00570 -0.01200 -0.01240 117 MET A C   
1515 O O   . MET A 113 ? 0.21780 0.27520 0.12910 0.01300  0.00630  -0.00930 117 MET A O   
1516 C CB  . MET A 113 ? 0.22020 0.26620 0.11160 0.00910  0.00740  -0.02430 117 MET A CB  
1517 C CG  . MET A 113 ? 0.26850 0.28640 0.11780 0.01660  -0.00670 -0.03340 117 MET A CG  
1518 S SD  . MET A 113 ? 0.37400 0.30780 0.15120 0.04550  -0.06810 -0.01860 117 MET A SD  
1519 C CE  . MET A 113 ? 0.34390 0.32540 0.19130 0.03340  -0.08090 0.02530  117 MET A CE  
1529 N N   . THR A 114 ? 0.16810 0.25410 0.12840 0.00000  -0.01640 -0.00610 118 THR A N   
1530 C CA  . THR A 114 ? 0.16660 0.26150 0.13400 -0.01870 -0.02070 0.00830  118 THR A CA  
1531 C C   . THR A 114 ? 0.15670 0.25700 0.14090 -0.01880 -0.02810 0.00850  118 THR A C   
1532 O O   . THR A 114 ? 0.17040 0.25290 0.12360 -0.03040 -0.01770 -0.00650 118 THR A O   
1533 C CB  . THR A 114 ? 0.18640 0.26590 0.14330 -0.02860 -0.02860 -0.00840 118 THR A CB  
1534 O OG1 . THR A 114 ? 0.18590 0.26510 0.13740 -0.02830 -0.02530 -0.00090 118 THR A OG1 
1535 C CG2 . THR A 114 ? 0.17820 0.26630 0.16560 -0.03610 -0.03400 -0.00820 118 THR A CG2 
1543 N N   . VAL A 115 ? 0.15290 0.24810 0.14660 0.00550  -0.03400 -0.00400 119 VAL A N   
1544 C CA  . VAL A 115 ? 0.15390 0.24420 0.14410 0.00420  -0.03140 0.00350  119 VAL A CA  
1545 C C   . VAL A 115 ? 0.16490 0.25410 0.15800 -0.01200 -0.05020 0.01640  119 VAL A C   
1546 O O   . VAL A 115 ? 0.17910 0.24690 0.14600 -0.03280 -0.05090 0.01960  119 VAL A O   
1547 C CB  . VAL A 115 ? 0.16220 0.26110 0.14950 0.00140  -0.03280 -0.00150 119 VAL A CB  
1548 C CG1 . VAL A 115 ? 0.17840 0.26310 0.16520 0.00350  -0.04190 -0.00460 119 VAL A CG1 
1549 C CG2 . VAL A 115 ? 0.19500 0.25590 0.16980 0.00080  -0.01890 -0.01470 119 VAL A CG2 
1559 N N   . ALA A 116 ? 0.17020 0.26000 0.14180 -0.01700 -0.04850 -0.00750 120 ALA A N   
1560 C CA  . ALA A 116 ? 0.18730 0.25880 0.14430 -0.02170 -0.03960 0.00280  120 ALA A CA  
1561 C C   . ALA A 116 ? 0.16400 0.26230 0.14240 -0.01940 -0.02980 0.00900  120 ALA A C   
1562 O O   . ALA A 116 ? 0.17220 0.26330 0.13880 -0.03800 -0.03420 -0.00830 120 ALA A O   
1563 C CB  . ALA A 116 ? 0.22760 0.25370 0.14350 -0.01780 -0.03200 -0.00410 120 ALA A CB  
1569 N N   . GLU A 117 ? 0.15180 0.26650 0.13980 -0.01660 -0.03720 0.00270  121 GLU A N   
1570 C CA  . GLU A 117 ? 0.13140 0.27900 0.13150 -0.01580 -0.04260 0.00320  121 GLU A CA  
1571 C C   . GLU A 117 ? 0.13820 0.27910 0.12940 -0.01430 -0.03490 0.00720  121 GLU A C   
1572 O O   . GLU A 117 ? 0.13950 0.27650 0.13770 -0.01510 -0.03080 0.00140  121 GLU A O   
1573 C CB  . GLU A 117 ? 0.13160 0.30220 0.13880 -0.00800 -0.03190 0.01540  121 GLU A CB  
1574 C CG  . GLU A 117 ? 0.15410 0.32750 0.13460 -0.02220 -0.03620 0.01050  121 GLU A CG  
1575 C CD  . GLU A 117 ? 0.16010 0.36040 0.13570 -0.00810 -0.04120 0.00290  121 GLU A CD  
1576 O OE1 . GLU A 117 ? 0.15880 0.32920 0.14940 -0.00010 -0.02490 0.00650  121 GLU A OE1 
1577 O OE2 . GLU A 117 ? 0.16390 0.41800 0.14810 0.00110  -0.03360 -0.00200 121 GLU A OE2 
1584 N N   . LEU A 118 ? 0.13170 0.27370 0.13780 -0.00780 -0.01570 0.00600  122 LEU A N   
1585 C CA  . LEU A 118 ? 0.13020 0.27720 0.11320 -0.02270 -0.02980 -0.00070 122 LEU A CA  
1586 C C   . LEU A 118 ? 0.15550 0.28340 0.10850 -0.02640 -0.01610 0.00330  122 LEU A C   
1587 O O   . LEU A 118 ? 0.15240 0.28540 0.11380 -0.02650 -0.01300 0.00810  122 LEU A O   
1588 C CB  . LEU A 118 ? 0.16680 0.28610 0.12790 -0.04120 -0.00890 -0.00550 122 LEU A CB  
1589 C CG  . LEU A 118 ? 0.21430 0.28790 0.13450 -0.04270 0.00190  -0.01010 122 LEU A CG  
1590 C CD1 . LEU A 118 ? 0.23460 0.29450 0.14200 -0.05090 0.03060  -0.00520 122 LEU A CD1 
1591 C CD2 . LEU A 118 ? 0.25900 0.28580 0.11860 -0.04650 -0.01110 -0.01820 122 LEU A CD2 
1603 N N   . SER A 119 ? 0.17840 0.27360 0.10800 -0.01730 -0.01630 0.00670  123 SER A N   
1604 C CA  . SER A 119 ? 0.17170 0.26220 0.11570 -0.02200 -0.02950 0.01460  123 SER A CA  
1605 C C   . SER A 119 ? 0.16350 0.25910 0.11490 -0.03430 -0.03510 0.02250  123 SER A C   
1606 O O   . SER A 119 ? 0.17430 0.27180 0.11790 -0.02480 -0.03840 0.02460  123 SER A O   
1607 C CB  . SER A 119 ? 0.18350 0.25820 0.13100 -0.01210 -0.02610 0.01060  123 SER A CB  
1608 O OG  . SER A 119 ? 0.19150 0.25670 0.15460 0.00070  -0.04310 -0.01170 123 SER A OG  
1614 N N   . ALA A 120 ? 0.16400 0.26050 0.13800 -0.02700 -0.04560 0.01830  124 ALA A N   
1615 C CA  . ALA A 120 ? 0.15080 0.28130 0.14070 -0.02890 -0.01820 0.01290  124 ALA A CA  
1616 C C   . ALA A 120 ? 0.14390 0.27820 0.12710 -0.02530 -0.02180 -0.00210 124 ALA A C   
1617 O O   . ALA A 120 ? 0.15060 0.29080 0.13510 -0.02250 -0.00330 -0.00310 124 ALA A O   
1618 C CB  . ALA A 120 ? 0.16870 0.28880 0.17320 -0.05240 -0.02980 0.01090  124 ALA A CB  
1624 N N   . ALA A 121 ? 0.14250 0.24990 0.11850 -0.01780 -0.02090 0.01440  125 ALA A N   
1625 C CA  . ALA A 121 ? 0.14270 0.24640 0.12610 -0.01710 0.00090  0.00360  125 ALA A CA  
1626 C C   . ALA A 121 ? 0.14360 0.25270 0.10780 -0.02540 0.00500  0.00670  125 ALA A C   
1627 O O   . ALA A 121 ? 0.15510 0.24630 0.11020 -0.02780 -0.01430 0.00250  125 ALA A O   
1628 C CB  . ALA A 121 ? 0.16690 0.23950 0.13840 -0.02340 -0.01800 0.02420  125 ALA A CB  
1634 N N   . ALA A 122 ? 0.13440 0.26760 0.12010 -0.03470 -0.00880 0.00520  126 ALA A N   
1635 C CA  . ALA A 122 ? 0.12790 0.27720 0.12170 -0.04300 -0.01540 -0.00380 126 ALA A CA  
1636 C C   . ALA A 122 ? 0.12760 0.27220 0.10690 -0.05400 -0.00690 0.01010  126 ALA A C   
1637 O O   . ALA A 122 ? 0.15110 0.27090 0.11430 -0.04980 -0.02830 0.02500  126 ALA A O   
1638 C CB  . ALA A 122 ? 0.14410 0.25770 0.09970 -0.05370 -0.01580 -0.00960 126 ALA A CB  
1644 N N   . VAL A 123 ? 0.13430 0.25010 0.12250 -0.03820 -0.01170 0.00460  127 VAL A N   
1645 C CA  . VAL A 123 ? 0.12600 0.26380 0.10280 -0.02110 -0.00020 -0.01130 127 VAL A CA  
1646 C C   . VAL A 123 ? 0.15040 0.26930 0.09970 -0.01910 -0.00150 0.00030  127 VAL A C   
1647 O O   . VAL A 123 ? 0.15000 0.27630 0.12610 -0.01800 -0.01030 -0.02380 127 VAL A O   
1648 C CB  . VAL A 123 ? 0.13760 0.27670 0.11620 -0.01480 -0.00720 0.00160  127 VAL A CB  
1649 C CG1 . VAL A 123 ? 0.16420 0.26960 0.11500 -0.00850 -0.01120 0.01430  127 VAL A CG1 
1650 C CG2 . VAL A 123 ? 0.14810 0.27260 0.11270 -0.01880 -0.00920 -0.00880 127 VAL A CG2 
1660 N N   . GLN A 124 ? 0.14570 0.27420 0.10280 -0.01580 -0.01320 0.00540  128 GLN A N   
1661 C CA  . GLN A 124 ? 0.16210 0.27430 0.10510 -0.01570 -0.00750 0.00200  128 GLN A CA  
1662 C C   . GLN A 124 ? 0.14600 0.26940 0.11570 -0.01430 -0.02620 0.00650  128 GLN A C   
1663 O O   . GLN A 124 ? 0.12810 0.26630 0.13750 0.00080  -0.01130 0.00980  128 GLN A O   
1664 C CB  . GLN A 124 ? 0.18190 0.28630 0.12640 -0.02420 -0.01440 0.01270  128 GLN A CB  
1665 C CG  . GLN A 124 ? 0.18620 0.28440 0.12480 -0.03500 -0.01040 0.02450  128 GLN A CG  
1666 C CD  . GLN A 124 ? 0.19270 0.30020 0.15810 -0.03130 -0.02000 0.02950  128 GLN A CD  
1667 O OE1 . GLN A 124 ? 0.21670 0.32420 0.22800 -0.03910 -0.06920 0.02630  128 GLN A OE1 
1668 N NE2 . GLN A 124 ? 0.20130 0.30470 0.18100 -0.04510 -0.00700 0.03950  128 GLN A NE2 
1677 N N   . TYR A 125 ? 0.15180 0.26190 0.12610 -0.02380 -0.01860 0.00710  129 TYR A N   
1678 C CA  . TYR A 125 ? 0.15060 0.26290 0.13500 -0.03040 -0.00530 0.02280  129 TYR A CA  
1679 C C   . TYR A 125 ? 0.15830 0.25470 0.15140 -0.02880 -0.03540 0.00380  129 TYR A C   
1680 O O   . TYR A 125 ? 0.16100 0.24640 0.20240 -0.02940 -0.04660 0.02960  129 TYR A O   
1681 C CB  . TYR A 125 ? 0.13800 0.28760 0.11320 -0.03420 -0.01210 0.03090  129 TYR A CB  
1682 C CG  . TYR A 125 ? 0.15260 0.32990 0.11580 -0.02780 -0.02420 0.02000  129 TYR A CG  
1683 C CD1 . TYR A 125 ? 0.15610 0.35000 0.14410 -0.04840 -0.04160 0.01840  129 TYR A CD1 
1684 C CD2 . TYR A 125 ? 0.16520 0.35440 0.14680 -0.01840 -0.04250 0.01910  129 TYR A CD2 
1685 C CE1 . TYR A 125 ? 0.16520 0.37620 0.16650 -0.03750 -0.05040 0.01700  129 TYR A CE1 
1686 C CE2 . TYR A 125 ? 0.13580 0.38010 0.16650 -0.01770 -0.03320 0.01680  129 TYR A CE2 
1687 C CZ  . TYR A 125 ? 0.12820 0.39940 0.19350 -0.03740 -0.03200 0.02650  129 TYR A CZ  
1688 O OH  . TYR A 125 ? 0.16900 0.44460 0.24990 -0.05340 -0.02870 0.03310  129 TYR A OH  
1698 N N   . SER A 126 ? 0.14770 0.26300 0.13640 -0.01490 -0.03150 0.00060  130 SER A N   
1699 C CA  . SER A 126 ? 0.16300 0.26320 0.13440 -0.02590 -0.00950 -0.00550 130 SER A CA  
1700 C C   . SER A 126 ? 0.18210 0.27350 0.13630 -0.02450 -0.00690 0.00790  130 SER A C   
1701 O O   . SER A 126 ? 0.21520 0.28520 0.12760 -0.03500 -0.02320 0.01280  130 SER A O   
1702 C CB  . SER A 126 ? 0.14660 0.25860 0.14980 -0.01590 -0.01920 0.00130  130 SER A CB  
1703 O OG  . SER A 126 ? 0.15180 0.24480 0.13090 -0.01610 -0.02260 0.01600  130 SER A OG  
1709 N N   . ASP A 127 ? 0.18840 0.25830 0.13010 -0.03930 -0.02850 0.01790  131 ASP A N   
1710 C CA  . ASP A 127 ? 0.16620 0.26770 0.10810 -0.03700 -0.02740 0.04210  131 ASP A CA  
1711 C C   . ASP A 127 ? 0.18420 0.26970 0.13010 -0.04130 -0.02670 0.02410  131 ASP A C   
1712 O O   . ASP A 127 ? 0.18170 0.27420 0.12340 -0.04010 -0.03110 0.02740  131 ASP A O   
1713 C CB  . ASP A 127 ? 0.15930 0.27660 0.11580 -0.03610 -0.02070 0.02350  131 ASP A CB  
1714 C CG  . ASP A 127 ? 0.16070 0.29320 0.13100 -0.02470 -0.02000 0.01660  131 ASP A CG  
1715 O OD1 . ASP A 127 ? 0.14930 0.28840 0.12250 -0.04240 -0.02200 0.01510  131 ASP A OD1 
1716 O OD2 . ASP A 127 ? 0.16010 0.31480 0.12030 -0.01400 -0.03020 0.00300  131 ASP A OD2 
1721 N N   . ASN A 128 ? 0.18400 0.26180 0.12570 -0.04150 -0.01200 0.01360  132 ASN A N   
1722 C CA  . ASN A 128 ? 0.18130 0.27270 0.14070 -0.02700 -0.01090 0.02490  132 ASN A CA  
1723 C C   . ASN A 128 ? 0.15760 0.28000 0.15030 -0.01940 -0.00700 0.04380  132 ASN A C   
1724 O O   . ASN A 128 ? 0.14670 0.28780 0.16440 -0.02730 -0.01330 0.03410  132 ASN A O   
1725 C CB  . ASN A 128 ? 0.21840 0.27770 0.13800 -0.03220 -0.01530 0.03160  132 ASN A CB  
1726 C CG  . ASN A 128 ? 0.23860 0.27990 0.13700 -0.04310 -0.02390 0.02000  132 ASN A CG  
1727 O OD1 . ASN A 128 ? 0.26040 0.28690 0.15330 -0.05630 -0.04320 0.02940  132 ASN A OD1 
1728 N ND2 . ASN A 128 ? 0.24930 0.29320 0.14490 -0.03570 -0.03290 0.00750  132 ASN A ND2 
1735 N N   . ALA A 129 ? 0.14500 0.29290 0.14420 -0.01080 -0.00340 0.03380  133 ALA A N   
1736 C CA  . ALA A 129 ? 0.15340 0.30200 0.14740 -0.00930 0.00530  0.01610  133 ALA A CA  
1737 C C   . ALA A 129 ? 0.15830 0.30170 0.12180 -0.02370 -0.01500 0.00620  133 ALA A C   
1738 O O   . ALA A 129 ? 0.17150 0.32480 0.12070 -0.02080 -0.01020 0.00990  133 ALA A O   
1739 C CB  . ALA A 129 ? 0.16860 0.31100 0.13520 -0.01200 -0.01440 0.02380  133 ALA A CB  
1745 N N   . ALA A 130 ? 0.15160 0.27590 0.11990 -0.03910 -0.01550 0.01090  134 ALA A N   
1746 C CA  . ALA A 130 ? 0.16070 0.26650 0.13090 -0.04140 -0.01000 0.02020  134 ALA A CA  
1747 C C   . ALA A 130 ? 0.17290 0.27560 0.13720 -0.02420 0.00220  0.01540  134 ALA A C   
1748 O O   . ALA A 130 ? 0.19000 0.27610 0.14420 -0.00520 -0.01620 0.01860  134 ALA A O   
1749 C CB  . ALA A 130 ? 0.17390 0.26110 0.13450 -0.04620 0.00230  0.01650  134 ALA A CB  
1755 N N   . ALA A 131 ? 0.16900 0.27200 0.13470 -0.02460 -0.00100 0.01380  135 ALA A N   
1756 C CA  . ALA A 131 ? 0.17500 0.29280 0.12790 -0.01270 -0.01210 0.02950  135 ALA A CA  
1757 C C   . ALA A 131 ? 0.17400 0.31510 0.13570 -0.02380 -0.02530 0.01610  135 ALA A C   
1758 O O   . ALA A 131 ? 0.17230 0.30880 0.13510 -0.01140 -0.01640 0.00650  135 ALA A O   
1759 C CB  . ALA A 131 ? 0.19750 0.30050 0.11700 -0.00510 -0.00070 0.03080  135 ALA A CB  
1765 N N   A ASN A 132 ? 0.18040 0.32210 0.13660 -0.02490 -0.02460 0.01640  136 ASN A N   
1766 N N   B ASN A 132 ? 0.17810 0.32230 0.13430 -0.02370 -0.02440 0.01540  136 ASN A N   
1767 C CA  A ASN A 132 ? 0.19520 0.33300 0.16730 -0.03040 -0.02440 0.01890  136 ASN A CA  
1768 C CA  B ASN A 132 ? 0.19030 0.33300 0.16610 -0.02710 -0.02260 0.01540  136 ASN A CA  
1769 C C   A ASN A 132 ? 0.15590 0.34170 0.14030 -0.03050 -0.02000 0.01840  136 ASN A C   
1770 C C   B ASN A 132 ? 0.15280 0.34190 0.13890 -0.03010 -0.02030 0.01780  136 ASN A C   
1771 O O   A ASN A 132 ? 0.15820 0.35080 0.13990 -0.01810 -0.01000 0.00810  136 ASN A O   
1772 O O   B ASN A 132 ? 0.15730 0.35210 0.13930 -0.01770 -0.00970 0.00760  136 ASN A O   
1773 C CB  A ASN A 132 ? 0.27530 0.34420 0.22320 -0.05080 -0.02150 0.03210  136 ASN A CB  
1774 C CB  B ASN A 132 ? 0.26630 0.34440 0.22610 -0.04300 -0.00950 0.01940  136 ASN A CB  
1775 C CG  A ASN A 132 ? 0.35420 0.35290 0.28140 -0.06370 -0.05640 0.05580  136 ASN A CG  
1776 C CG  B ASN A 132 ? 0.34220 0.35320 0.31030 -0.04970 -0.02980 0.02800  136 ASN A CG  
1777 O OD1 A ASN A 132 ? 0.38070 0.35420 0.27350 -0.08540 -0.05410 0.05250  136 ASN A OD1 
1778 O OD1 B ASN A 132 ? 0.33510 0.35350 0.35360 -0.05860 -0.02520 0.00720  136 ASN A OD1 
1779 N ND2 A ASN A 132 ? 0.36250 0.35960 0.29720 -0.06180 -0.07940 0.06420  136 ASN A ND2 
1780 N ND2 B ASN A 132 ? 0.39420 0.36030 0.33040 -0.06480 -0.03120 0.04120  136 ASN A ND2 
1793 N N   . LEU A 133 ? 0.15110 0.34400 0.12180 -0.02570 -0.01620 0.02180  137 LEU A N   
1794 C CA  . LEU A 133 ? 0.16570 0.34610 0.11430 -0.01580 -0.02220 0.00280  137 LEU A CA  
1795 C C   . LEU A 133 ? 0.17080 0.35330 0.12810 -0.01780 -0.03770 -0.01090 137 LEU A C   
1796 O O   . LEU A 133 ? 0.19250 0.36610 0.15290 -0.01210 -0.02160 -0.02730 137 LEU A O   
1797 C CB  . LEU A 133 ? 0.16490 0.34960 0.14020 0.00400  -0.02830 0.00580  137 LEU A CB  
1798 C CG  . LEU A 133 ? 0.17120 0.36170 0.13910 0.01500  -0.02610 0.00710  137 LEU A CG  
1799 C CD1 . LEU A 133 ? 0.17850 0.37030 0.16470 0.01170  -0.03990 0.01300  137 LEU A CD1 
1800 C CD2 . LEU A 133 ? 0.20360 0.37300 0.16600 0.01160  -0.00820 0.02670  137 LEU A CD2 
1812 N N   . LEU A 134 ? 0.17360 0.33050 0.11110 -0.02910 -0.02890 -0.01150 138 LEU A N   
1813 C CA  . LEU A 134 ? 0.15870 0.31470 0.14610 -0.02600 -0.03320 0.00030  138 LEU A CA  
1814 C C   . LEU A 134 ? 0.17080 0.31780 0.16350 -0.02120 -0.03220 0.00010  138 LEU A C   
1815 O O   . LEU A 134 ? 0.17870 0.31060 0.17510 0.00030  -0.01690 -0.01630 138 LEU A O   
1816 C CB  . LEU A 134 ? 0.15950 0.31050 0.18310 -0.02170 -0.01410 0.00410  138 LEU A CB  
1817 C CG  . LEU A 134 ? 0.14680 0.29820 0.19200 -0.02000 -0.02660 0.02260  138 LEU A CG  
1818 C CD1 . LEU A 134 ? 0.14050 0.29260 0.19150 -0.01560 -0.00210 0.04200  138 LEU A CD1 
1819 C CD2 . LEU A 134 ? 0.16910 0.29700 0.20370 -0.01690 -0.03440 0.03180  138 LEU A CD2 
1831 N N   . LEU A 135 ? 0.17980 0.31850 0.14520 -0.01290 -0.03290 0.00230  139 LEU A N   
1832 C CA  A LEU A 135 ? 0.19150 0.32060 0.16470 0.00410  -0.02410 0.00270  139 LEU A CA  
1833 C CA  B LEU A 135 ? 0.17480 0.31470 0.17010 0.00500  -0.03330 0.00820  139 LEU A CA  
1834 C C   . LEU A 135 ? 0.18910 0.34470 0.18370 0.01940  -0.01480 0.00800  139 LEU A C   
1835 O O   . LEU A 135 ? 0.18590 0.36440 0.19910 0.03640  -0.00090 0.01900  139 LEU A O   
1836 C CB  A LEU A 135 ? 0.21670 0.31260 0.18050 0.00210  -0.00850 0.00360  139 LEU A CB  
1837 C CB  B LEU A 135 ? 0.16800 0.29720 0.19930 0.00470  -0.03450 0.02230  139 LEU A CB  
1838 C CG  A LEU A 135 ? 0.23500 0.30320 0.15960 0.01750  -0.00600 0.00250  139 LEU A CG  
1839 C CG  B LEU A 135 ? 0.15160 0.27990 0.17560 0.02230  -0.03690 0.02810  139 LEU A CG  
1840 C CD1 A LEU A 135 ? 0.23970 0.29610 0.15840 0.02290  0.00640  -0.00630 139 LEU A CD1 
1841 C CD1 B LEU A 135 ? 0.17230 0.26740 0.15740 0.01860  -0.06750 0.03960  139 LEU A CD1 
1842 C CD2 A LEU A 135 ? 0.24260 0.30860 0.16500 0.01880  -0.03680 -0.00090 139 LEU A CD2 
1843 C CD2 B LEU A 135 ? 0.13280 0.27840 0.17580 0.02700  -0.02780 0.04070  139 LEU A CD2 
1866 N N   . LYS A 136 ? 0.19750 0.37570 0.20260 0.03660  0.01270  0.00770  140 LYS A N   
1867 C CA  . LYS A 136 ? 0.24450 0.42150 0.21690 0.06380  0.02700  -0.01990 140 LYS A CA  
1868 C C   . LYS A 136 ? 0.25600 0.43230 0.19720 0.06440  0.02190  -0.03590 140 LYS A C   
1869 O O   . LYS A 136 ? 0.29330 0.44970 0.22700 0.07690  0.03010  -0.02920 140 LYS A O   
1870 C CB  . LYS A 136 ? 0.28970 0.45400 0.24900 0.07300  0.06270  -0.03200 140 LYS A CB  
1871 C CG  . LYS A 136 ? 0.36240 0.48160 0.34870 0.06050  0.03940  -0.04130 140 LYS A CG  
1872 C CD  . LYS A 136 ? 0.40750 0.50320 0.41560 0.05310  0.01540  -0.04180 140 LYS A CD  
1873 C CE  . LYS A 136 ? 0.44720 0.51660 0.44510 0.05490  0.00960  -0.03410 140 LYS A CE  
1874 N NZ  . LYS A 136 ? 0.46360 0.52320 0.42620 0.06180  0.01910  -0.03710 140 LYS A NZ  
1888 N N   . GLU A 137 ? 0.23070 0.42870 0.20160 0.06080  -0.01820 -0.05880 141 GLU A N   
1889 C CA  . GLU A 137 ? 0.28290 0.42120 0.25460 0.05010  -0.00910 -0.07770 141 GLU A CA  
1890 C C   . GLU A 137 ? 0.28900 0.39850 0.26100 0.03570  -0.02570 -0.07700 141 GLU A C   
1891 O O   . GLU A 137 ? 0.31380 0.40310 0.27050 0.03880  -0.05680 -0.07710 141 GLU A O   
1892 C CB  . GLU A 137 ? 0.34140 0.44370 0.30550 0.03240  -0.02870 -0.07270 141 GLU A CB  
1893 C CG  . GLU A 137 ? 0.43350 0.46500 0.36270 0.02330  -0.02240 -0.07580 141 GLU A CG  
1894 C CD  . GLU A 137 ? 0.49640 0.48000 0.39730 0.01740  -0.02900 -0.08200 141 GLU A CD  
1895 O OE1 . GLU A 137 ? 0.51680 0.48430 0.43230 0.01650  -0.03990 -0.09160 141 GLU A OE1 
1896 O OE2 . GLU A 137 ? 0.52560 0.49070 0.39400 0.01370  -0.02980 -0.06910 141 GLU A OE2 
1903 N N   . LEU A 138 ? 0.26630 0.37440 0.25590 0.01980  -0.02660 -0.08620 142 LEU A N   
1904 C CA  . LEU A 138 ? 0.28470 0.36430 0.25240 0.01730  -0.03520 -0.05830 142 LEU A CA  
1905 C C   . LEU A 138 ? 0.26700 0.36000 0.24740 0.00580  -0.04850 -0.03400 142 LEU A C   
1906 O O   . LEU A 138 ? 0.28760 0.37550 0.29680 0.01360  -0.06860 -0.00750 142 LEU A O   
1907 C CB  . LEU A 138 ? 0.34080 0.36660 0.29040 0.02960  -0.00330 -0.06020 142 LEU A CB  
1908 C CG  . LEU A 138 ? 0.38070 0.37240 0.33950 0.04490  0.02540  -0.06760 142 LEU A CG  
1909 C CD1 . LEU A 138 ? 0.41180 0.37950 0.35910 0.04240  0.04040  -0.05580 142 LEU A CD1 
1910 C CD2 . LEU A 138 ? 0.38750 0.37250 0.36860 0.03690  0.03310  -0.06240 142 LEU A CD2 
1922 N N   . GLY A 139 ? 0.24530 0.34820 0.23170 -0.00340 -0.01880 -0.04150 143 GLY A N   
1923 C CA  . GLY A 139 ? 0.22590 0.34760 0.25940 0.00820  -0.01590 -0.03810 143 GLY A CA  
1924 C C   . GLY A 139 ? 0.20050 0.33450 0.23360 0.00540  -0.02020 -0.03960 143 GLY A C   
1925 O O   . GLY A 139 ? 0.21210 0.34130 0.30380 0.00180  -0.02360 -0.04890 143 GLY A O   
1929 N N   . GLY A 140 ? 0.18970 0.31930 0.16590 0.01490  -0.02220 -0.02600 144 GLY A N   
1930 C CA  . GLY A 140 ? 0.17980 0.31230 0.14750 0.01490  -0.00480 -0.00920 144 GLY A CA  
1931 C C   . GLY A 140 ? 0.17500 0.31190 0.12740 0.02590  0.02120  -0.00600 144 GLY A C   
1932 O O   . GLY A 140 ? 0.17780 0.32880 0.14440 0.03440  -0.00750 -0.01360 144 GLY A O   
1936 N N   . PRO A 141 ? 0.19700 0.29690 0.11700 0.02410  0.01430  -0.00700 145 PRO A N   
1937 C CA  . PRO A 141 ? 0.21440 0.29050 0.12170 0.03540  -0.00600 -0.00010 145 PRO A CA  
1938 C C   . PRO A 141 ? 0.19180 0.28200 0.13060 0.02670  0.00920  -0.00410 145 PRO A C   
1939 O O   . PRO A 141 ? 0.18660 0.27980 0.09840 0.04080  0.01080  0.00350  145 PRO A O   
1940 C CB  . PRO A 141 ? 0.22010 0.29200 0.11930 0.03130  -0.00530 0.02590  145 PRO A CB  
1941 C CG  . PRO A 141 ? 0.23560 0.30170 0.12640 0.04160  -0.00320 0.01650  145 PRO A CG  
1942 C CD  . PRO A 141 ? 0.20850 0.29320 0.11550 0.02990  0.00160  0.00220  145 PRO A CD  
1950 N N   . ALA A 142 ? 0.16570 0.27220 0.13920 0.02170  0.01290  -0.00290 146 ALA A N   
1951 C CA  . ALA A 142 ? 0.15510 0.27830 0.14430 0.02990  0.01750  -0.00910 146 ALA A CA  
1952 C C   . ALA A 142 ? 0.16160 0.28280 0.13880 0.03620  0.01050  -0.02290 146 ALA A C   
1953 O O   . ALA A 142 ? 0.17640 0.28430 0.14200 0.02110  0.00580  -0.01300 146 ALA A O   
1954 C CB  . ALA A 142 ? 0.15570 0.27980 0.17430 0.02540  0.03090  0.00330  146 ALA A CB  
1960 N N   . GLY A 143 ? 0.15200 0.27780 0.12550 0.01440  0.00660  -0.01600 147 GLY A N   
1961 C CA  . GLY A 143 ? 0.13330 0.27340 0.15380 0.00380  -0.00490 -0.02860 147 GLY A CA  
1962 C C   . GLY A 143 ? 0.15510 0.27150 0.13360 0.00280  -0.00480 -0.01670 147 GLY A C   
1963 O O   . GLY A 143 ? 0.16130 0.27930 0.16480 0.01100  0.00210  -0.01800 147 GLY A O   
1967 N N   . LEU A 144 ? 0.14680 0.25970 0.12380 0.01650  0.01170  0.00770  148 LEU A N   
1968 C CA  . LEU A 144 ? 0.12540 0.25440 0.13890 0.01780  -0.00420 -0.00740 148 LEU A CA  
1969 C C   . LEU A 144 ? 0.13830 0.25550 0.13630 0.01340  -0.00740 -0.00780 148 LEU A C   
1970 O O   . LEU A 144 ? 0.14260 0.25610 0.13630 0.02160  -0.00450 -0.02310 148 LEU A O   
1971 C CB  . LEU A 144 ? 0.15180 0.24880 0.13040 0.02310  -0.00210 -0.02790 148 LEU A CB  
1972 C CG  . LEU A 144 ? 0.16480 0.23580 0.12810 0.02290  0.00420  -0.02150 148 LEU A CG  
1973 C CD1 . LEU A 144 ? 0.19140 0.23110 0.16750 0.01840  0.00850  0.00900  148 LEU A CD1 
1974 C CD2 . LEU A 144 ? 0.21060 0.24860 0.11850 0.01860  0.00170  -0.03570 148 LEU A CD2 
1986 N N   . THR A 145 ? 0.12430 0.24220 0.12850 0.02140  -0.00260 -0.00180 149 THR A N   
1987 C CA  . THR A 145 ? 0.12910 0.23040 0.11590 0.01080  0.01220  -0.02460 149 THR A CA  
1988 C C   . THR A 145 ? 0.16060 0.22930 0.13750 0.02090  0.01590  -0.03980 149 THR A C   
1989 O O   . THR A 145 ? 0.16680 0.22590 0.13640 0.00030  0.00700  -0.01150 149 THR A O   
1990 C CB  . THR A 145 ? 0.15110 0.22340 0.11560 0.01080  0.00470  -0.01960 149 THR A CB  
1991 O OG1 . THR A 145 ? 0.16060 0.21870 0.11670 0.00810  0.00920  -0.00580 149 THR A OG1 
1992 C CG2 . THR A 145 ? 0.13700 0.23570 0.13370 0.01880  0.00010  -0.00360 149 THR A CG2 
2000 N N   . ALA A 146 ? 0.17590 0.21870 0.14950 0.02010  0.01400  -0.06950 150 ALA A N   
2001 C CA  . ALA A 146 ? 0.16420 0.22760 0.18500 0.02390  0.00960  -0.06590 150 ALA A CA  
2002 C C   . ALA A 146 ? 0.15370 0.23800 0.17610 0.02090  0.01400  -0.03940 150 ALA A C   
2003 O O   . ALA A 146 ? 0.14270 0.22430 0.19440 0.00960  -0.00270 -0.01670 150 ALA A O   
2004 C CB  . ALA A 146 ? 0.17600 0.23850 0.20640 0.03980  0.01730  -0.06250 150 ALA A CB  
2010 N N   . PHE A 147 ? 0.14820 0.23620 0.16620 0.01580  -0.00260 -0.01820 151 PHE A N   
2011 C CA  . PHE A 147 ? 0.16820 0.23550 0.15000 -0.00850 0.00520  -0.02010 151 PHE A CA  
2012 C C   . PHE A 147 ? 0.16350 0.23430 0.15220 -0.00820 -0.01170 -0.01830 151 PHE A C   
2013 O O   . PHE A 147 ? 0.16440 0.24790 0.16810 0.00880  -0.00560 -0.02120 151 PHE A O   
2014 C CB  . PHE A 147 ? 0.18590 0.24210 0.16090 -0.01170 0.00430  -0.01160 151 PHE A CB  
2015 C CG  . PHE A 147 ? 0.16780 0.25790 0.15850 0.00710  -0.02210 -0.02150 151 PHE A CG  
2016 C CD1 . PHE A 147 ? 0.17240 0.26490 0.16210 -0.00380 -0.00670 -0.01890 151 PHE A CD1 
2017 C CD2 . PHE A 147 ? 0.18440 0.27020 0.17630 0.00700  -0.02290 -0.02270 151 PHE A CD2 
2018 C CE1 . PHE A 147 ? 0.17220 0.25980 0.17650 -0.00820 -0.01820 -0.02120 151 PHE A CE1 
2019 C CE2 . PHE A 147 ? 0.17950 0.26980 0.17410 0.01190  -0.02440 -0.00980 151 PHE A CE2 
2020 C CZ  . PHE A 147 ? 0.17020 0.26850 0.16770 0.00860  -0.01090 -0.01040 151 PHE A CZ  
2030 N N   . MET A 148 ? 0.14030 0.21060 0.14160 0.00910  -0.00660 -0.02150 152 MET A N   
2031 C CA  . MET A 148 ? 0.15780 0.22410 0.12870 0.02630  0.00420  -0.01730 152 MET A CA  
2032 C C   . MET A 148 ? 0.14270 0.22960 0.14780 0.01560  0.00850  -0.00350 152 MET A C   
2033 O O   . MET A 148 ? 0.15430 0.23820 0.14700 0.01520  0.00300  0.00470  152 MET A O   
2034 C CB  . MET A 148 ? 0.16630 0.22920 0.12610 0.01960  -0.00180 -0.01570 152 MET A CB  
2035 C CG  . MET A 148 ? 0.15190 0.22590 0.12710 0.01650  0.01120  -0.02940 152 MET A CG  
2036 S SD  . MET A 148 ? 0.14540 0.19850 0.16160 -0.00490 0.00200  -0.00400 152 MET A SD  
2037 C CE  . MET A 148 ? 0.16140 0.24110 0.14160 -0.02660 0.02110  -0.00490 152 MET A CE  
2047 N N   . ARG A 149 ? 0.15990 0.23060 0.13920 0.01820  0.00230  0.00180  153 ARG A N   
2048 C CA  . ARG A 149 ? 0.14710 0.22060 0.14860 0.00860  0.00830  0.00690  153 ARG A CA  
2049 C C   . ARG A 149 ? 0.15980 0.21240 0.17730 -0.00060 0.02010  0.00990  153 ARG A C   
2050 O O   . ARG A 149 ? 0.17070 0.21700 0.18230 0.01120  0.01800  0.01600  153 ARG A O   
2051 C CB  . ARG A 149 ? 0.14940 0.22520 0.15250 0.01980  -0.00200 0.02330  153 ARG A CB  
2052 C CG  . ARG A 149 ? 0.15120 0.23550 0.16750 0.03540  0.00360  0.01820  153 ARG A CG  
2053 C CD  . ARG A 149 ? 0.14430 0.24940 0.15530 0.02980  0.01870  0.00270  153 ARG A CD  
2054 N NE  . ARG A 149 ? 0.13580 0.25030 0.14510 0.01020  0.02610  -0.00950 153 ARG A NE  
2055 C CZ  . ARG A 149 ? 0.13750 0.23730 0.13970 0.03740  0.01400  -0.02090 153 ARG A CZ  
2056 N NH1 . ARG A 149 ? 0.13270 0.22350 0.14820 0.04200  0.01960  -0.00890 153 ARG A NH1 
2057 N NH2 . ARG A 149 ? 0.13030 0.24540 0.13960 0.01350  0.02090  -0.00080 153 ARG A NH2 
2071 N N   . SER A 150 ? 0.16020 0.18000 0.19300 -0.00660 0.01050  -0.02870 154 SER A N   
2072 C CA  . SER A 150 ? 0.19350 0.20310 0.19530 -0.00010 0.01940  -0.04090 154 SER A CA  
2073 C C   . SER A 150 ? 0.20150 0.20970 0.20470 -0.01680 0.02340  -0.01890 154 SER A C   
2074 O O   . SER A 150 ? 0.23610 0.21610 0.23210 -0.00570 0.04260  -0.01180 154 SER A O   
2075 C CB  . SER A 150 ? 0.23640 0.21800 0.22300 0.00370  0.01370  -0.05160 154 SER A CB  
2076 O OG  . SER A 150 ? 0.24480 0.21900 0.21080 -0.00390 0.00950  -0.05140 154 SER A OG  
2082 N N   . ILE A 151 ? 0.17640 0.22420 0.19530 -0.00400 0.01810  0.00200  155 ILE A N   
2083 C CA  . ILE A 151 ? 0.16950 0.23590 0.18570 -0.01160 0.01250  0.00820  155 ILE A CA  
2084 C C   . ILE A 151 ? 0.17510 0.23120 0.19130 0.01130  0.02320  0.02250  155 ILE A C   
2085 O O   . ILE A 151 ? 0.19750 0.25680 0.20640 0.00420  0.02290  0.01250  155 ILE A O   
2086 C CB  . ILE A 151 ? 0.16490 0.23650 0.18960 -0.00590 0.01990  -0.00650 155 ILE A CB  
2087 C CG1 . ILE A 151 ? 0.16080 0.22340 0.18800 0.03010  0.01370  -0.01060 155 ILE A CG1 
2088 C CG2 . ILE A 151 ? 0.18230 0.23380 0.21140 -0.00620 0.02150  -0.01730 155 ILE A CG2 
2089 C CD1 . ILE A 151 ? 0.17360 0.21910 0.17370 0.03070  -0.00890 -0.00320 155 ILE A CD1 
2101 N N   . GLY A 152 ? 0.15470 0.21950 0.18270 0.01960  0.02470  0.03560  156 GLY A N   
2102 C CA  . GLY A 152 ? 0.15860 0.22950 0.19790 0.03160  0.00110  0.02880  156 GLY A CA  
2103 C C   . GLY A 152 ? 0.16550 0.23210 0.16810 0.01290  -0.01110 0.02380  156 GLY A C   
2104 O O   . GLY A 152 ? 0.19480 0.24560 0.16480 -0.00460 -0.02750 0.01580  156 GLY A O   
2108 N N   . ASP A 153 ? 0.13160 0.21300 0.15250 0.01190  0.02080  0.02410  157 ASP A N   
2109 C CA  . ASP A 153 ? 0.16480 0.20990 0.14030 0.01960  0.01450  -0.00490 157 ASP A CA  
2110 C C   . ASP A 153 ? 0.15690 0.20790 0.14590 0.02410  -0.00430 0.00130  157 ASP A C   
2111 O O   . ASP A 153 ? 0.17930 0.20640 0.13840 0.03140  0.01510  0.02150  157 ASP A O   
2112 C CB  . ASP A 153 ? 0.15920 0.20850 0.13370 0.01210  0.00240  0.01380  157 ASP A CB  
2113 C CG  . ASP A 153 ? 0.14900 0.22350 0.12140 0.00550  0.01980  0.00840  157 ASP A CG  
2114 O OD1 . ASP A 153 ? 0.12870 0.21420 0.13650 -0.00230 0.00900  0.01100  157 ASP A OD1 
2115 O OD2 . ASP A 153 ? 0.14050 0.23720 0.13530 0.02210  0.01970  0.00150  157 ASP A OD2 
2120 N N   . THR A 154 ? 0.16100 0.22840 0.14730 0.01110  0.00200  0.01470  158 THR A N   
2121 C CA  . THR A 154 ? 0.14570 0.23890 0.15500 0.00830  0.01560  0.01700  158 THR A CA  
2122 C C   . THR A 154 ? 0.13450 0.23540 0.12950 0.00040  0.01540  0.01400  158 THR A C   
2123 O O   . THR A 154 ? 0.12270 0.24690 0.17490 0.01950  0.01670  0.02370  158 THR A O   
2124 C CB  . THR A 154 ? 0.16970 0.26000 0.18340 0.01120  -0.00500 0.03260  158 THR A CB  
2125 O OG1 . THR A 154 ? 0.19010 0.28720 0.20100 0.01010  -0.03310 0.03760  158 THR A OG1 
2126 C CG2 . THR A 154 ? 0.19040 0.26650 0.22630 0.01380  -0.00660 0.04430  158 THR A CG2 
2134 N N   . THR A 155 ? 0.13970 0.22850 0.11570 0.02570  0.01010  0.00440  159 THR A N   
2135 C CA  . THR A 155 ? 0.12070 0.20880 0.12450 0.00980  0.00380  0.00660  159 THR A CA  
2136 C C   . THR A 155 ? 0.13150 0.20540 0.12030 0.01450  0.02500  0.01110  159 THR A C   
2137 O O   . THR A 155 ? 0.12620 0.21320 0.12800 -0.00060 0.00850  0.00440  159 THR A O   
2138 C CB  . THR A 155 ? 0.14050 0.22820 0.11850 0.02270  0.02850  0.01120  159 THR A CB  
2139 O OG1 . THR A 155 ? 0.16720 0.24410 0.11440 0.02970  0.01650  0.03290  159 THR A OG1 
2140 C CG2 . THR A 155 ? 0.15030 0.24540 0.12550 0.03570  0.03000  0.01440  159 THR A CG2 
2148 N N   . PHE A 156 ? 0.13780 0.18590 0.11520 -0.00910 0.01940  0.00210  160 PHE A N   
2149 C CA  . PHE A 156 ? 0.14690 0.19750 0.10580 -0.01290 0.01980  0.02310  160 PHE A CA  
2150 C C   . PHE A 156 ? 0.13480 0.22280 0.11090 -0.01530 0.00490  0.01490  160 PHE A C   
2151 O O   . PHE A 156 ? 0.14250 0.23760 0.11070 -0.00480 0.01030  0.00960  160 PHE A O   
2152 C CB  . PHE A 156 ? 0.14050 0.19920 0.11960 -0.01330 0.01330  -0.00270 160 PHE A CB  
2153 C CG  . PHE A 156 ? 0.15360 0.19800 0.11360 0.01220  0.01270  0.00010  160 PHE A CG  
2154 C CD1 . PHE A 156 ? 0.15260 0.20650 0.11810 0.00890  -0.00650 0.01820  160 PHE A CD1 
2155 C CD2 . PHE A 156 ? 0.16610 0.19150 0.12660 0.00820  0.01290  -0.00410 160 PHE A CD2 
2156 C CE1 . PHE A 156 ? 0.16310 0.20630 0.13800 -0.00590 0.00230  -0.00150 160 PHE A CE1 
2157 C CE2 . PHE A 156 ? 0.15470 0.20760 0.15390 0.00000  -0.00170 -0.00930 160 PHE A CE2 
2158 C CZ  . PHE A 156 ? 0.15510 0.21050 0.14940 -0.00260 -0.01220 -0.01450 160 PHE A CZ  
2168 N N   . ARG A 157 ? 0.11330 0.21740 0.09870 0.01280  0.02240  -0.00230 161 ARG A N   
2169 C CA  . ARG A 157 ? 0.13740 0.21810 0.12300 0.00480  0.01790  0.01220  161 ARG A CA  
2170 C C   . ARG A 157 ? 0.14470 0.22870 0.11780 0.01050  0.03050  0.00750  161 ARG A C   
2171 O O   . ARG A 157 ? 0.16350 0.24190 0.10140 0.03940  0.01370  0.01730  161 ARG A O   
2172 C CB  . ARG A 157 ? 0.15670 0.21960 0.13890 -0.00510 0.01040  0.00830  161 ARG A CB  
2173 C CG  . ARG A 157 ? 0.13120 0.21960 0.13260 0.00020  0.01690  0.00380  161 ARG A CG  
2174 C CD  . ARG A 157 ? 0.14860 0.22490 0.14970 0.01320  0.01330  0.01160  161 ARG A CD  
2175 N NE  . ARG A 157 ? 0.15790 0.23180 0.14790 0.01250  -0.00150 0.00060  161 ARG A NE  
2176 C CZ  . ARG A 157 ? 0.16850 0.25490 0.14870 0.00440  0.01560  -0.00780 161 ARG A CZ  
2177 N NH1 . ARG A 157 ? 0.15530 0.27370 0.13840 0.00830  -0.00440 -0.01530 161 ARG A NH1 
2178 N NH2 . ARG A 157 ? 0.16480 0.25630 0.15830 0.01450  0.01720  -0.00720 161 ARG A NH2 
2192 N N   . LEU A 158 ? 0.13660 0.21680 0.10400 -0.00270 0.01330  0.00820  162 LEU A N   
2193 C CA  . LEU A 158 ? 0.14770 0.22820 0.11400 0.01260  0.01670  0.00770  162 LEU A CA  
2194 C C   . LEU A 158 ? 0.16090 0.23650 0.12060 0.02440  0.02080  -0.00430 162 LEU A C   
2195 O O   . LEU A 158 ? 0.14370 0.23220 0.12310 0.02030  0.01270  0.02400  162 LEU A O   
2196 C CB  . LEU A 158 ? 0.14700 0.22550 0.11990 0.01640  -0.00790 -0.00210 162 LEU A CB  
2197 C CG  . LEU A 158 ? 0.17090 0.23510 0.13000 0.00980  -0.00150 -0.00720 162 LEU A CG  
2198 C CD1 . LEU A 158 ? 0.15730 0.24600 0.15410 0.01040  -0.01870 -0.01080 162 LEU A CD1 
2199 C CD2 . LEU A 158 ? 0.18410 0.23440 0.15840 0.01770  -0.01120 0.00080  162 LEU A CD2 
2211 N N   . ASP A 159 ? 0.18070 0.24130 0.14650 0.00370  0.01370  0.00270  163 ASP A N   
2212 C CA  . ASP A 159 ? 0.17530 0.24450 0.13000 0.01450  0.02600  0.01040  163 ASP A CA  
2213 C C   . ASP A 159 ? 0.23310 0.26590 0.12800 0.03090  0.03340  0.00130  163 ASP A C   
2214 O O   . ASP A 159 ? 0.24900 0.28160 0.12880 0.04220  0.05480  -0.01220 163 ASP A O   
2215 C CB  . ASP A 159 ? 0.15740 0.25090 0.14240 0.01950  0.04320  0.00350  163 ASP A CB  
2216 C CG  . ASP A 159 ? 0.14180 0.25340 0.13550 0.01970  0.02270  -0.00850 163 ASP A CG  
2217 O OD1 . ASP A 159 ? 0.14230 0.23590 0.12900 0.01640  0.03210  0.01610  163 ASP A OD1 
2218 O OD2 . ASP A 159 ? 0.15710 0.27190 0.14330 0.01930  0.01960  -0.01930 163 ASP A OD2 
2223 N N   . ARG A 160 ? 0.26660 0.26860 0.12560 0.05390  0.02630  0.03730  164 ARG A N   
2224 C CA  . ARG A 160 ? 0.31720 0.28010 0.14980 0.05100  0.03510  0.04440  164 ARG A CA  
2225 C C   . ARG A 160 ? 0.35960 0.31390 0.19190 0.04510  -0.01640 0.01310  164 ARG A C   
2226 O O   . ARG A 160 ? 0.30840 0.30960 0.15490 0.07910  -0.01850 -0.02910 164 ARG A O   
2227 C CB  . ARG A 160 ? 0.33980 0.28560 0.16230 0.03040  0.04380  0.04910  164 ARG A CB  
2228 C CG  . ARG A 160 ? 0.33740 0.28320 0.15880 0.02370  0.06980  0.04410  164 ARG A CG  
2229 C CD  . ARG A 160 ? 0.32610 0.27770 0.16290 0.03240  0.07570  0.04230  164 ARG A CD  
2230 N NE  . ARG A 160 ? 0.28500 0.26980 0.17710 0.03760  0.06580  0.03620  164 ARG A NE  
2231 C CZ  . ARG A 160 ? 0.27390 0.27360 0.18990 0.02050  0.04600  0.01610  164 ARG A CZ  
2232 N NH1 . ARG A 160 ? 0.30350 0.28340 0.20700 0.01540  0.04310  0.01720  164 ARG A NH1 
2233 N NH2 . ARG A 160 ? 0.25650 0.26220 0.13750 0.02880  0.05620  -0.00700 164 ARG A NH2 
2247 N N   A TRP A 161 ? 0.37720 0.32510 0.23100 0.03460  -0.02570 0.01760  165 TRP A N   
2248 N N   B TRP A 161 ? 0.38830 0.33200 0.24360 0.03530  -0.02350 0.01250  165 TRP A N   
2249 N N   C TRP A 161 ? 0.40120 0.33530 0.21390 0.02840  -0.04630 0.02520  165 TRP A N   
2250 C CA  A TRP A 161 ? 0.39080 0.33700 0.26520 0.02630  -0.02940 0.01860  165 TRP A CA  
2251 C CA  B TRP A 161 ? 0.40640 0.35200 0.28660 0.02820  -0.02410 0.00860  165 TRP A CA  
2252 C CA  C TRP A 161 ? 0.41350 0.35040 0.18830 0.01650  -0.06160 0.02770  165 TRP A CA  
2253 C C   A TRP A 161 ? 0.40230 0.34590 0.29170 0.02080  -0.02800 0.01860  165 TRP A C   
2254 C C   B TRP A 161 ? 0.42140 0.36540 0.31470 0.02400  -0.01890 0.00330  165 TRP A C   
2255 C C   C TRP A 161 ? 0.40980 0.35970 0.20420 -0.00550 -0.04680 0.03940  165 TRP A C   
2256 O O   A TRP A 161 ? 0.41560 0.34800 0.29290 0.01890  -0.03390 0.02220  165 TRP A O   
2257 O O   B TRP A 161 ? 0.43060 0.36810 0.31860 0.02000  -0.02240 0.00870  165 TRP A O   
2258 O O   C TRP A 161 ? 0.45130 0.36750 0.17270 -0.01900 -0.04310 0.04360  165 TRP A O   
2259 C CB  A TRP A 161 ? 0.38920 0.34000 0.27290 0.02370  -0.03000 0.01960  165 TRP A CB  
2260 C CB  B TRP A 161 ? 0.40820 0.35870 0.30460 0.02640  -0.02270 0.00940  165 TRP A CB  
2261 C CB  C TRP A 161 ? 0.41460 0.35440 0.18570 0.02540  -0.05970 0.02590  165 TRP A CB  
2262 C CG  A TRP A 161 ? 0.38660 0.34290 0.28420 0.02040  -0.02980 0.02070  165 TRP A CG  
2263 C CG  B TRP A 161 ? 0.40930 0.36490 0.32730 0.02270  -0.02390 0.01050  165 TRP A CG  
2264 C CG  C TRP A 161 ? 0.41370 0.35510 0.22140 0.02920  -0.06030 0.03520  165 TRP A CG  
2265 C CD1 A TRP A 161 ? 0.38490 0.34370 0.29000 0.01930  -0.03100 0.02180  165 TRP A CD1 
2266 C CD1 B TRP A 161 ? 0.40970 0.36640 0.33690 0.02210  -0.02560 0.01160  165 TRP A CD1 
2267 C CD1 C TRP A 161 ? 0.40710 0.35350 0.25040 0.02930  -0.05490 0.03760  165 TRP A CD1 
2268 C CD2 A TRP A 161 ? 0.38350 0.34430 0.28800 0.01610  -0.02360 0.02160  165 TRP A CD2 
2269 C CD2 B TRP A 161 ? 0.40860 0.36830 0.33620 0.01690  -0.01870 0.01140  165 TRP A CD2 
2270 C CD2 C TRP A 161 ? 0.40590 0.35230 0.22150 0.01540  -0.04270 0.04260  165 TRP A CD2 
2271 N NE1 A TRP A 161 ? 0.38460 0.34430 0.29330 0.01740  -0.03180 0.02280  165 TRP A NE1 
2272 N NE1 B TRP A 161 ? 0.41100 0.36790 0.34270 0.02010  -0.02760 0.01340  165 TRP A NE1 
2273 N NE1 C TRP A 161 ? 0.41530 0.34900 0.26160 0.02490  -0.07150 0.04500  165 TRP A NE1 
2274 C CE2 A TRP A 161 ? 0.38390 0.34490 0.29220 0.01590  -0.02500 0.02280  165 TRP A CE2 
2275 C CE2 B TRP A 161 ? 0.41040 0.36920 0.34240 0.01680  -0.02080 0.01360  165 TRP A CE2 
2276 C CE2 C TRP A 161 ? 0.41550 0.35010 0.24580 0.02040  -0.05060 0.04880  165 TRP A CE2 
2277 C CE3 A TRP A 161 ? 0.38270 0.34550 0.28960 0.01530  -0.01450 0.02180  165 TRP A CE3 
2278 C CE3 B TRP A 161 ? 0.41010 0.37110 0.34080 0.01510  -0.00730 0.01110  165 TRP A CE3 
2279 C CE3 C TRP A 161 ? 0.41070 0.35550 0.22990 0.01650  -0.00430 0.03960  165 TRP A CE3 
2280 C CZ2 A TRP A 161 ? 0.38240 0.34520 0.29220 0.01500  -0.01910 0.02200  165 TRP A CZ2 
2281 C CZ2 B TRP A 161 ? 0.40950 0.37020 0.34280 0.01630  -0.01460 0.01200  165 TRP A CZ2 
2282 C CZ2 C TRP A 161 ? 0.41230 0.35030 0.24030 0.02070  -0.03670 0.03950  165 TRP A CZ2 
2283 C CZ3 A TRP A 161 ? 0.38140 0.34590 0.29200 0.01390  -0.01130 0.02150  165 TRP A CZ3 
2284 C CZ3 B TRP A 161 ? 0.40950 0.37230 0.34530 0.01400  -0.00470 0.01050  165 TRP A CZ3 
2285 C CZ3 C TRP A 161 ? 0.40880 0.35640 0.25070 0.01650  0.00160  0.03540  165 TRP A CZ3 
2286 C CH2 A TRP A 161 ? 0.38180 0.34630 0.29360 0.01430  -0.01280 0.02080  165 TRP A CH2 
2287 C CH2 B TRP A 161 ? 0.40880 0.37260 0.34640 0.01560  -0.00860 0.01010  165 TRP A CH2 
2288 C CH2 C TRP A 161 ? 0.41260 0.35750 0.25820 0.02170  -0.01170 0.03050  165 TRP A CH2 
2319 N N   A GLN A 162 ? 0.39740 0.35350 0.31460 0.01720  -0.01900 0.01490  166 GLN A N   
2320 N N   B GLN A 162 ? 0.42740 0.37850 0.33630 0.02200  -0.01000 -0.00370 166 GLN A N   
2321 N N   C GLN A 162 ? 0.38840 0.36550 0.22910 -0.01360 -0.03220 0.03220  166 GLN A N   
2322 C CA  A GLN A 162 ? 0.39210 0.36050 0.33600 0.01430  -0.00880 0.01150  166 GLN A CA  
2323 C CA  B GLN A 162 ? 0.43000 0.38470 0.35570 0.01710  0.00180  -0.00610 166 GLN A CA  
2324 C CA  C GLN A 162 ? 0.34920 0.37750 0.27140 -0.01970 -0.02390 0.00450  166 GLN A CA  
2325 C C   A GLN A 162 ? 0.38940 0.36270 0.33500 0.01590  -0.00180 0.01330  166 GLN A C   
2326 C C   B GLN A 162 ? 0.42820 0.39190 0.37440 0.01560  0.00700  -0.00390 166 GLN A C   
2327 C C   C GLN A 162 ? 0.35310 0.38370 0.27540 -0.01180 -0.03270 -0.01210 166 GLN A C   
2328 O O   A GLN A 162 ? 0.38480 0.36280 0.33880 0.01490  -0.00360 0.00970  166 GLN A O   
2329 O O   B GLN A 162 ? 0.42320 0.39650 0.39380 0.01210  0.01220  -0.00670 166 GLN A O   
2330 O O   C GLN A 162 ? 0.34100 0.38800 0.22530 -0.00420 -0.06000 -0.02970 166 GLN A O   
2331 C CB  A GLN A 162 ? 0.39200 0.36500 0.35490 0.01060  -0.00490 0.00680  166 GLN A CB  
2332 C CB  B GLN A 162 ? 0.43050 0.38650 0.36080 0.00540  0.01000  -0.00740 166 GLN A CB  
2333 C CB  C GLN A 162 ? 0.34760 0.39140 0.32020 -0.03120 0.00220  -0.00900 166 GLN A CB  
2334 C CG  A GLN A 162 ? 0.39200 0.36930 0.36920 0.00770  -0.00170 0.00400  166 GLN A CG  
2335 C CG  B GLN A 162 ? 0.42750 0.38910 0.36310 -0.00010 0.00850  -0.01190 166 GLN A CG  
2336 C CG  C GLN A 162 ? 0.32170 0.40470 0.34530 -0.03760 0.02470  -0.01010 166 GLN A CG  
2337 C CD  A GLN A 162 ? 0.39240 0.37240 0.37970 0.00540  0.00090  0.00170  166 GLN A CD  
2338 C CD  B GLN A 162 ? 0.41540 0.38870 0.34690 0.00100  0.00970  -0.01410 166 GLN A CD  
2339 C CD  C GLN A 162 ? 0.29060 0.40780 0.32920 -0.03800 0.04690  -0.01860 166 GLN A CD  
2340 O OE1 A GLN A 162 ? 0.39260 0.37350 0.38250 0.00450  0.00200  0.00070  166 GLN A OE1 
2341 O OE1 B GLN A 162 ? 0.43020 0.39240 0.35700 0.00490  0.00470  -0.01910 166 GLN A OE1 
2342 O OE1 C GLN A 162 ? 0.29790 0.41720 0.34610 -0.04020 0.03640  -0.02110 166 GLN A OE1 
2343 N NE2 A GLN A 162 ? 0.39270 0.37360 0.38330 0.00520  0.00200  0.00040  166 GLN A NE2 
2344 N NE2 B GLN A 162 ? 0.40680 0.39270 0.33210 0.00430  -0.00130 -0.00960 166 GLN A NE2 
2345 N NE2 C GLN A 162 ? 0.26590 0.40160 0.32810 -0.05160 0.07180  -0.01270 166 GLN A NE2 
2367 N N   A LEU A 163 ? 0.39520 0.36440 0.32430 0.01990  0.00810  0.02050  167 LEU A N   
2368 N N   B LEU A 163 ? 0.42200 0.38990 0.37410 0.01490  0.00790  0.00630  167 LEU A N   
2369 N N   C LEU A 163 ? 0.37290 0.38890 0.29790 0.00180  -0.01720 -0.00670 167 LEU A N   
2370 C CA  A LEU A 163 ? 0.38810 0.36770 0.31920 0.01610  0.02680  0.03450  167 LEU A CA  
2371 C CA  B LEU A 163 ? 0.41100 0.38940 0.37320 0.01160  0.01240  0.01690  167 LEU A CA  
2372 C CA  C LEU A 163 ? 0.38560 0.39170 0.32430 0.00680  -0.00720 0.00620  167 LEU A CA  
2373 C C   A LEU A 163 ? 0.38310 0.36640 0.27810 0.01180  0.05670  0.06260  167 LEU A C   
2374 C C   B LEU A 163 ? 0.39960 0.38220 0.34940 0.01110  0.02890  0.03200  167 LEU A C   
2375 C C   C LEU A 163 ? 0.38490 0.38430 0.30010 0.01120  0.00390  0.01970  167 LEU A C   
2376 O O   A LEU A 163 ? 0.37630 0.35570 0.20040 -0.00160 0.08690  0.09480  167 LEU A O   
2377 O O   B LEU A 163 ? 0.39920 0.37860 0.32650 0.01010  0.03620  0.03750  167 LEU A O   
2378 O O   C LEU A 163 ? 0.38830 0.37820 0.25630 0.00790  0.01800  0.03670  167 LEU A O   
2379 C CB  A LEU A 163 ? 0.38440 0.37340 0.34790 0.01270  0.01240  0.03340  167 LEU A CB  
2380 C CB  B LEU A 163 ? 0.40820 0.39570 0.39110 0.00820  0.00040  0.01660  167 LEU A CB  
2381 C CB  C LEU A 163 ? 0.39220 0.40220 0.36570 0.00460  -0.01300 0.01460  167 LEU A CB  
2382 C CG  A LEU A 163 ? 0.38400 0.37700 0.36750 0.00860  0.00880  0.03580  167 LEU A CG  
2383 C CG  B LEU A 163 ? 0.40700 0.40090 0.40350 0.00400  -0.00380 0.01690  167 LEU A CG  
2384 C CG  C LEU A 163 ? 0.39920 0.41030 0.39410 0.00070  -0.00780 0.02530  167 LEU A CG  
2385 C CD1 A LEU A 163 ? 0.38530 0.37930 0.37900 0.00640  0.00410  0.03800  167 LEU A CD1 
2386 C CD1 B LEU A 163 ? 0.40370 0.40260 0.40550 0.00110  -0.00640 0.01820  167 LEU A CD1 
2387 C CD1 C LEU A 163 ? 0.40020 0.41350 0.40420 -0.00320 -0.00590 0.03210  167 LEU A CD1 
2388 C CD2 A LEU A 163 ? 0.38090 0.37890 0.36470 0.00450  0.00790  0.03540  167 LEU A CD2 
2389 C CD2 B LEU A 163 ? 0.40600 0.40330 0.40440 0.00180  -0.00500 0.01570  167 LEU A CD2 
2390 C CD2 C LEU A 163 ? 0.39940 0.41460 0.39780 -0.00280 -0.00760 0.02700  167 LEU A CD2 
2421 N N   A GLU A 164 ? 0.38810 0.37490 0.28450 0.01040  0.06450  0.07300  168 GLU A N   
2422 N N   B GLU A 164 ? 0.38970 0.37730 0.33410 0.00890  0.04440  0.04270  168 GLU A N   
2423 C CA  A GLU A 164 ? 0.37790 0.37350 0.26980 0.00310  0.08320  0.07520  168 GLU A CA  
2424 C CA  B GLU A 164 ? 0.37270 0.36860 0.31130 0.00600  0.05790  0.04800  168 GLU A CA  
2425 C C   A GLU A 164 ? 0.33190 0.34690 0.23810 0.01170  0.08210  0.06840  168 GLU A C   
2426 C C   B GLU A 164 ? 0.33650 0.34590 0.25750 0.00850  0.06030  0.05660  168 GLU A C   
2427 O O   A GLU A 164 ? 0.31440 0.33930 0.26100 0.01390  0.09170  0.06760  168 GLU A O   
2428 O O   B GLU A 164 ? 0.32720 0.34130 0.26900 0.00380  0.06420  0.06040  168 GLU A O   
2429 C CB  A GLU A 164 ? 0.41450 0.39690 0.29220 0.00010  0.08860  0.07720  168 GLU A CB  
2430 C CB  B GLU A 164 ? 0.39450 0.38250 0.34600 0.00470  0.06090  0.04500  168 GLU A CB  
2431 C CG  A GLU A 164 ? 0.44810 0.41870 0.31500 -0.00680 0.08270  0.07910  168 GLU A CG  
2432 C CG  B GLU A 164 ? 0.41430 0.39570 0.37750 0.00250  0.05250  0.03940  168 GLU A CG  
2433 C CD  A GLU A 164 ? 0.47750 0.43220 0.33490 -0.01060 0.07000  0.08640  168 GLU A CD  
2434 C CD  B GLU A 164 ? 0.43040 0.40470 0.40490 0.00170  0.04740  0.04010  168 GLU A CD  
2435 O OE1 A GLU A 164 ? 0.48270 0.43460 0.31250 -0.01200 0.07220  0.09260  168 GLU A OE1 
2436 O OE1 B GLU A 164 ? 0.43870 0.40690 0.42040 0.00410  0.04430  0.03700  168 GLU A OE1 
2437 O OE2 A GLU A 164 ? 0.50110 0.44210 0.37670 -0.00700 0.05210  0.08460  168 GLU A OE2 
2438 O OE2 B GLU A 164 ? 0.43590 0.41030 0.40480 0.00410  0.05020  0.04050  168 GLU A OE2 
2451 N N   . LEU A 165 ? 0.31220 0.33080 0.19770 0.01280  0.04510  0.05870  169 LEU A N   
2452 C CA  . LEU A 165 ? 0.25140 0.31500 0.15380 -0.00180 0.00440  0.05360  169 LEU A CA  
2453 C C   . LEU A 165 ? 0.20820 0.31050 0.16070 -0.01420 -0.00830 0.02720  169 LEU A C   
2454 O O   . LEU A 165 ? 0.21480 0.31330 0.16700 -0.02530 -0.02170 0.02730  169 LEU A O   
2455 C CB  . LEU A 165 ? 0.21830 0.31040 0.15360 -0.00540 -0.00350 0.05080  169 LEU A CB  
2456 C CG  . LEU A 165 ? 0.20860 0.29880 0.16520 -0.01670 -0.01260 0.01310  169 LEU A CG  
2457 C CD1 . LEU A 165 ? 0.22330 0.30990 0.20210 -0.02470 -0.01020 0.00950  169 LEU A CD1 
2458 C CD2 . LEU A 165 ? 0.22580 0.30050 0.20150 -0.02400 -0.01440 0.01320  169 LEU A CD2 
2471 N N   . ASN A 166 ? 0.18710 0.29780 0.14550 -0.02740 -0.00930 0.02510  170 ASN A N   
2472 C CA  . ASN A 166 ? 0.16090 0.28490 0.14260 -0.02740 -0.01260 0.01580  170 ASN A CA  
2473 C C   . ASN A 166 ? 0.17050 0.25700 0.13500 -0.02320 -0.01520 0.00810  170 ASN A C   
2474 O O   . ASN A 166 ? 0.18420 0.25510 0.16150 -0.01710 0.00240  0.00370  170 ASN A O   
2475 C CB  . ASN A 166 ? 0.15660 0.31010 0.14670 -0.02780 -0.01250 0.04640  170 ASN A CB  
2476 C CG  . ASN A 166 ? 0.19810 0.32990 0.15920 -0.03480 -0.01810 0.04280  170 ASN A CG  
2477 O OD1 . ASN A 166 ? 0.18900 0.32870 0.19100 -0.06540 -0.04360 0.04480  170 ASN A OD1 
2478 N ND2 . ASN A 166 ? 0.21050 0.34050 0.17610 -0.03880 -0.02530 0.03480  170 ASN A ND2 
2485 N N   . SER A 167 ? 0.16440 0.24800 0.15300 -0.01110 0.00060  0.01450  171 SER A N   
2486 C CA  . SER A 167 ? 0.16650 0.24180 0.16070 0.00230  -0.00720 0.02560  171 SER A CA  
2487 C C   . SER A 167 ? 0.15240 0.22090 0.15570 -0.02890 0.00730  0.01050  171 SER A C   
2488 O O   . SER A 167 ? 0.17850 0.21580 0.16450 -0.03150 0.00030  0.00880  171 SER A O   
2489 C CB  . SER A 167 ? 0.21280 0.27240 0.17340 0.01680  0.00840  0.01560  171 SER A CB  
2490 O OG  . SER A 167 ? 0.20670 0.29750 0.16770 0.03570  0.00550  -0.00590 171 SER A OG  
2496 N N   . ALA A 168 ? 0.15550 0.23230 0.15290 -0.02490 0.02360  0.01310  172 ALA A N   
2497 C CA  . ALA A 168 ? 0.15140 0.23640 0.13700 -0.01020 -0.00200 0.02190  172 ALA A CA  
2498 C C   . ALA A 168 ? 0.14230 0.24370 0.12910 -0.01310 -0.00320 0.00220  172 ALA A C   
2499 O O   . ALA A 168 ? 0.14540 0.24310 0.14090 -0.01810 -0.00690 0.00510  172 ALA A O   
2500 C CB  . ALA A 168 ? 0.13770 0.23130 0.13090 -0.02390 0.00760  0.03460  172 ALA A CB  
2506 N N   . ILE A 169 ? 0.12810 0.23990 0.13810 -0.04340 0.00280  -0.01110 173 ILE A N   
2507 C CA  . ILE A 169 ? 0.12900 0.23190 0.13610 -0.02130 0.01300  0.00170  173 ILE A CA  
2508 C C   . ILE A 169 ? 0.13880 0.22560 0.13310 -0.00790 0.00750  0.02020  173 ILE A C   
2509 O O   . ILE A 169 ? 0.14530 0.23280 0.14040 -0.01560 -0.00680 0.00820  173 ILE A O   
2510 C CB  . ILE A 169 ? 0.14240 0.24590 0.13280 -0.02100 0.02010  -0.00480 173 ILE A CB  
2511 C CG1 . ILE A 169 ? 0.17770 0.27560 0.15650 -0.02320 0.01070  0.01460  173 ILE A CG1 
2512 C CG2 . ILE A 169 ? 0.12830 0.26220 0.13960 -0.01090 0.01840  -0.00150 173 ILE A CG2 
2513 C CD1 . ILE A 169 ? 0.20050 0.29320 0.18560 -0.02180 0.00030  0.04040  173 ILE A CD1 
2525 N N   . PRO A 170 ? 0.12370 0.20620 0.13630 0.00190  -0.00480 0.00580  174 PRO A N   
2526 C CA  . PRO A 170 ? 0.13110 0.20230 0.13760 -0.00210 -0.01000 -0.01160 174 PRO A CA  
2527 C C   . PRO A 170 ? 0.13920 0.20300 0.13160 -0.01940 -0.00790 -0.00540 174 PRO A C   
2528 O O   . PRO A 170 ? 0.13360 0.21450 0.17200 -0.01670 0.00130  0.00330  174 PRO A O   
2529 C CB  . PRO A 170 ? 0.15360 0.21520 0.15710 0.00320  -0.02300 -0.01670 174 PRO A CB  
2530 C CG  . PRO A 170 ? 0.17890 0.23250 0.16970 0.01600  0.00080  -0.01720 174 PRO A CG  
2531 C CD  . PRO A 170 ? 0.13430 0.21610 0.15460 -0.00720 0.00380  -0.02690 174 PRO A CD  
2539 N N   . GLY A 171 ? 0.16170 0.19690 0.14240 -0.00050 -0.00740 -0.00070 175 GLY A N   
2540 C CA  . GLY A 171 ? 0.16590 0.19310 0.16250 0.00530  -0.03280 0.00580  175 GLY A CA  
2541 C C   . GLY A 171 ? 0.15860 0.20100 0.17450 0.00730  -0.01320 -0.00620 175 GLY A C   
2542 O O   . GLY A 171 ? 0.19580 0.19670 0.18500 0.00550  -0.02080 -0.01600 175 GLY A O   
2546 N N   . ASP A 172 ? 0.15480 0.20980 0.13820 0.00050  -0.00950 0.00310  176 ASP A N   
2547 C CA  . ASP A 172 ? 0.13980 0.20190 0.15680 0.00770  -0.00390 -0.01090 176 ASP A CA  
2548 C C   . ASP A 172 ? 0.12100 0.20330 0.15340 -0.00120 -0.00070 -0.00860 176 ASP A C   
2549 O O   . ASP A 172 ? 0.11520 0.21850 0.19400 -0.00210 0.00080  0.00340  176 ASP A O   
2550 C CB  . ASP A 172 ? 0.16910 0.20850 0.14990 0.00400  0.01120  -0.00620 176 ASP A CB  
2551 C CG  . ASP A 172 ? 0.19270 0.22820 0.15910 -0.00850 0.02960  0.00170  176 ASP A CG  
2552 O OD1 . ASP A 172 ? 0.19720 0.21550 0.15960 -0.01670 0.04840  -0.00060 176 ASP A OD1 
2553 O OD2 . ASP A 172 ? 0.20540 0.26110 0.16830 -0.00080 0.02700  -0.00430 176 ASP A OD2 
2558 N N   . ALA A 173 ? 0.10830 0.21570 0.15590 -0.00130 -0.00090 -0.00350 177 ALA A N   
2559 C CA  . ALA A 173 ? 0.15180 0.21510 0.14810 -0.00440 0.01840  -0.00390 177 ALA A CA  
2560 C C   . ALA A 173 ? 0.14730 0.20470 0.12540 -0.01030 0.04070  0.00370  177 ALA A C   
2561 O O   . ALA A 173 ? 0.13890 0.21310 0.12940 0.01760  0.01600  -0.00630 177 ALA A O   
2562 C CB  . ALA A 173 ? 0.16050 0.20740 0.15860 -0.00540 -0.00360 -0.00240 177 ALA A CB  
2568 N N   . ARG A 174 ? 0.13980 0.20340 0.11740 -0.02860 0.01930  -0.00150 178 ARG A N   
2569 C CA  . ARG A 174 ? 0.13070 0.21210 0.11740 -0.03760 0.03250  -0.01090 178 ARG A CA  
2570 C C   . ARG A 174 ? 0.09780 0.22080 0.11720 -0.01110 0.02800  0.01250  178 ARG A C   
2571 O O   . ARG A 174 ? 0.13210 0.21870 0.12780 -0.00490 0.03740  -0.00270 178 ARG A O   
2572 C CB  . ARG A 174 ? 0.16770 0.21710 0.13890 -0.03820 0.03780  -0.00980 178 ARG A CB  
2573 C CG  . ARG A 174 ? 0.19330 0.22590 0.14200 -0.03030 0.03750  -0.00610 178 ARG A CG  
2574 C CD  . ARG A 174 ? 0.23460 0.22190 0.18280 -0.03700 0.06100  -0.00240 178 ARG A CD  
2575 N NE  . ARG A 174 ? 0.27890 0.22210 0.20170 -0.03530 0.10160  0.00790  178 ARG A NE  
2576 C CZ  . ARG A 174 ? 0.33510 0.22970 0.22250 -0.02400 0.14130  -0.01530 178 ARG A CZ  
2577 N NH1 . ARG A 174 ? 0.37480 0.25500 0.24170 -0.01930 0.15940  -0.01320 178 ARG A NH1 
2578 N NH2 . ARG A 174 ? 0.35000 0.22950 0.24660 -0.03400 0.14500  -0.02370 178 ARG A NH2 
2592 N N   . ASP A 175 ? 0.12760 0.20650 0.11810 0.00510  0.00380  0.01020  179 ASP A N   
2593 C CA  . ASP A 175 ? 0.12070 0.21730 0.10790 0.00050  0.00460  0.00480  179 ASP A CA  
2594 C C   . ASP A 175 ? 0.09590 0.22540 0.10310 0.00110  0.01050  -0.01690 179 ASP A C   
2595 O O   . ASP A 175 ? 0.11690 0.22390 0.10730 0.00160  0.00060  -0.00450 179 ASP A O   
2596 C CB  . ASP A 175 ? 0.13030 0.20790 0.09980 0.00440  0.01860  0.00170  179 ASP A CB  
2597 C CG  . ASP A 175 ? 0.18430 0.24530 0.12010 0.01500  0.02700  0.00850  179 ASP A CG  
2598 O OD1 . ASP A 175 ? 0.20220 0.23280 0.12450 0.04490  0.02200  0.00880  179 ASP A OD1 
2599 O OD2 . ASP A 175 ? 0.20270 0.25910 0.12130 0.01170  0.04020  0.00580  179 ASP A OD2 
2604 N N   . THR A 176 ? 0.11030 0.22690 0.10660 -0.01110 -0.00430 -0.00520 180 THR A N   
2605 C CA  . THR A 176 ? 0.12440 0.21800 0.10890 -0.01770 0.01390  -0.01350 180 THR A CA  
2606 C C   . THR A 176 ? 0.10230 0.22080 0.11680 -0.00700 0.01570  -0.00630 180 THR A C   
2607 O O   . THR A 176 ? 0.12580 0.22200 0.09400 -0.01930 0.00920  0.01160  180 THR A O   
2608 C CB  . THR A 176 ? 0.12080 0.21540 0.12500 0.00470  -0.00300 -0.01200 180 THR A CB  
2609 O OG1 . THR A 176 ? 0.14010 0.21680 0.11560 0.00290  -0.00270 0.00670  180 THR A OG1 
2610 C CG2 . THR A 176 ? 0.14460 0.21210 0.11420 -0.01840 0.00510  -0.02550 180 THR A CG2 
2618 N N   . SER A 177 ? 0.09660 0.21520 0.10680 -0.01830 0.01090  0.01930  181 SER A N   
2619 C CA  . SER A 177 ? 0.13320 0.17030 0.11320 -0.00850 0.01310  -0.00980 181 SER A CA  
2620 C C   . SER A 177 ? 0.14460 0.16210 0.10370 0.00380  -0.00670 -0.02590 181 SER A C   
2621 O O   . SER A 177 ? 0.16270 0.15930 0.10150 -0.01840 -0.00410 -0.01020 181 SER A O   
2622 C CB  . SER A 177 ? 0.15290 0.17340 0.11190 -0.01460 0.01040  0.00630  181 SER A CB  
2623 O OG  . SER A 177 ? 0.14960 0.16390 0.11180 -0.00940 -0.00480 -0.00130 181 SER A OG  
2629 N N   . SER A 178 ? 0.13650 0.15500 0.11590 0.00240  0.00530  -0.02420 182 SER A N   
2630 C CA  . SER A 178 ? 0.11840 0.16350 0.10200 0.00370  0.00370  0.00050  182 SER A CA  
2631 C C   . SER A 178 ? 0.13210 0.17890 0.09550 -0.01630 -0.00950 0.00750  182 SER A C   
2632 O O   . SER A 178 ? 0.12990 0.17420 0.10650 -0.01250 -0.00410 0.00830  182 SER A O   
2633 C CB  . SER A 178 ? 0.12190 0.15440 0.10520 0.01290  0.01420  0.01480  182 SER A CB  
2634 O OG  . SER A 178 ? 0.13380 0.16030 0.11550 0.02230  -0.00530 0.03380  182 SER A OG  
2640 N N   . PRO A 179 ? 0.14140 0.18050 0.09420 0.00050  0.00540  0.01790  183 PRO A N   
2641 C CA  . PRO A 179 ? 0.13640 0.20980 0.10520 0.00950  0.00450  0.02010  183 PRO A CA  
2642 C C   . PRO A 179 ? 0.12630 0.22610 0.08780 0.01000  -0.00290 0.02750  183 PRO A C   
2643 O O   . PRO A 179 ? 0.12760 0.21660 0.10900 -0.00070 0.00200  0.01260  183 PRO A O   
2644 C CB  . PRO A 179 ? 0.14410 0.19060 0.12890 0.00920  0.01320  0.01010  183 PRO A CB  
2645 C CG  . PRO A 179 ? 0.13970 0.18970 0.12710 0.01780  0.02650  -0.00340 183 PRO A CG  
2646 C CD  . PRO A 179 ? 0.12250 0.19130 0.11130 0.02370  0.00450  -0.00640 183 PRO A CD  
2654 N N   . ARG A 180 ? 0.13160 0.22050 0.09580 -0.00020 -0.00130 0.03240  184 ARG A N   
2655 C CA  . ARG A 180 ? 0.13670 0.21390 0.10370 0.01100  -0.01210 0.03990  184 ARG A CA  
2656 C C   . ARG A 180 ? 0.10980 0.20600 0.11760 0.01380  0.00860  0.04820  184 ARG A C   
2657 O O   . ARG A 180 ? 0.12350 0.22250 0.11360 0.01880  0.01800  0.02740  184 ARG A O   
2658 C CB  . ARG A 180 ? 0.15900 0.22520 0.10250 0.02930  -0.01080 0.03480  184 ARG A CB  
2659 C CG  . ARG A 180 ? 0.17140 0.23260 0.10660 0.03310  -0.03380 0.02870  184 ARG A CG  
2660 C CD  . ARG A 180 ? 0.18460 0.25280 0.13940 0.02470  -0.00930 0.01500  184 ARG A CD  
2661 N NE  . ARG A 180 ? 0.20640 0.27580 0.14700 0.02920  -0.03920 0.02590  184 ARG A NE  
2662 C CZ  . ARG A 180 ? 0.26610 0.28280 0.20230 0.04190  -0.05910 0.03070  184 ARG A CZ  
2663 N NH1 . ARG A 180 ? 0.27560 0.27940 0.21140 0.03440  -0.05970 0.03180  184 ARG A NH1 
2664 N NH2 . ARG A 180 ? 0.31000 0.28540 0.23040 0.03750  -0.07350 0.04450  184 ARG A NH2 
2678 N N   . ALA A 181 ? 0.12330 0.18710 0.12000 -0.00890 -0.00090 0.02240  185 ALA A N   
2679 C CA  . ALA A 181 ? 0.14530 0.20350 0.12170 0.00790  -0.02050 0.00980  185 ALA A CA  
2680 C C   . ALA A 181 ? 0.12610 0.21320 0.11460 0.00800  0.01660  0.00700  185 ALA A C   
2681 O O   . ALA A 181 ? 0.14760 0.22100 0.11150 0.01700  0.01390  0.00890  185 ALA A O   
2682 C CB  . ALA A 181 ? 0.11750 0.21860 0.12200 0.00110  0.01080  0.00750  185 ALA A CB  
2688 N N   . VAL A 182 ? 0.13050 0.20690 0.11450 -0.00710 0.01030  0.01340  186 VAL A N   
2689 C CA  . VAL A 182 ? 0.11790 0.18990 0.12360 -0.00370 -0.00360 0.03380  186 VAL A CA  
2690 C C   . VAL A 182 ? 0.13470 0.19540 0.11930 -0.00550 -0.00310 0.03500  186 VAL A C   
2691 O O   . VAL A 182 ? 0.13020 0.19210 0.12850 -0.00800 -0.00180 0.01350  186 VAL A O   
2692 C CB  . VAL A 182 ? 0.12760 0.19260 0.12210 -0.00480 -0.01650 0.03120  186 VAL A CB  
2693 C CG1 . VAL A 182 ? 0.12580 0.18440 0.14130 -0.00740 -0.01950 0.01660  186 VAL A CG1 
2694 C CG2 . VAL A 182 ? 0.11920 0.21180 0.10760 -0.02380 -0.01590 0.03590  186 VAL A CG2 
2704 N N   . THR A 183 ? 0.13720 0.20410 0.12410 -0.01130 -0.00440 0.02790  187 THR A N   
2705 C CA  . THR A 183 ? 0.13390 0.20260 0.12780 -0.02220 -0.00970 0.02160  187 THR A CA  
2706 C C   . THR A 183 ? 0.13580 0.20860 0.10900 -0.00900 0.00000  0.01450  187 THR A C   
2707 O O   . THR A 183 ? 0.13420 0.20030 0.13270 0.00600  0.00130  0.02730  187 THR A O   
2708 C CB  . THR A 183 ? 0.14810 0.20990 0.13710 -0.02650 0.00610  0.01970  187 THR A CB  
2709 O OG1 . THR A 183 ? 0.20220 0.20980 0.13430 0.00550  -0.00450 0.01490  187 THR A OG1 
2710 C CG2 . THR A 183 ? 0.15360 0.24910 0.16810 -0.04030 0.04080  0.01070  187 THR A CG2 
2718 N N   . GLU A 184 ? 0.12290 0.18200 0.12860 -0.00140 0.01170  0.00820  188 GLU A N   
2719 C CA  . GLU A 184 ? 0.16360 0.18590 0.14390 -0.00180 0.00580  -0.01310 188 GLU A CA  
2720 C C   . GLU A 184 ? 0.14960 0.18980 0.15030 -0.01490 0.01610  -0.00540 188 GLU A C   
2721 O O   . GLU A 184 ? 0.14440 0.21200 0.14710 -0.01090 -0.00200 0.00700  188 GLU A O   
2722 C CB  . GLU A 184 ? 0.16860 0.20970 0.13740 0.00730  -0.00420 0.01040  188 GLU A CB  
2723 C CG  . GLU A 184 ? 0.17710 0.23310 0.13530 0.01120  -0.01640 0.00820  188 GLU A CG  
2724 C CD  . GLU A 184 ? 0.18010 0.26660 0.13950 -0.00060 0.00060  0.00680  188 GLU A CD  
2725 O OE1 . GLU A 184 ? 0.15580 0.29050 0.16740 0.01130  0.00810  -0.00590 188 GLU A OE1 
2726 O OE2 . GLU A 184 ? 0.20580 0.27460 0.14620 0.01020  -0.01880 0.01740  188 GLU A OE2 
2733 N N   . SER A 185 ? 0.13800 0.19300 0.13770 -0.00370 0.02320  0.00140  189 SER A N   
2734 C CA  . SER A 185 ? 0.12290 0.19600 0.14580 -0.03250 0.00210  0.00300  189 SER A CA  
2735 C C   . SER A 185 ? 0.12400 0.19670 0.15180 -0.01930 0.00220  0.01000  189 SER A C   
2736 O O   . SER A 185 ? 0.14080 0.18900 0.15330 -0.01930 -0.00690 0.02040  189 SER A O   
2737 C CB  . SER A 185 ? 0.11910 0.22010 0.13310 -0.02870 -0.00380 -0.00400 189 SER A CB  
2738 O OG  . SER A 185 ? 0.14840 0.23170 0.13700 -0.00410 0.01240  0.00790  189 SER A OG  
2744 N N   . LEU A 186 ? 0.11240 0.20400 0.15460 -0.00100 0.01440  0.00160  190 LEU A N   
2745 C CA  . LEU A 186 ? 0.10690 0.20350 0.14470 0.00350  0.00110  0.02160  190 LEU A CA  
2746 C C   . LEU A 186 ? 0.12170 0.20790 0.13760 0.01880  0.00260  0.02760  190 LEU A C   
2747 O O   . LEU A 186 ? 0.13320 0.21470 0.15220 -0.00460 -0.00410 0.00780  190 LEU A O   
2748 C CB  . LEU A 186 ? 0.12530 0.21470 0.12960 -0.00940 0.00980  0.02100  190 LEU A CB  
2749 C CG  . LEU A 186 ? 0.11960 0.22470 0.13650 -0.00690 0.01620  0.03160  190 LEU A CG  
2750 C CD1 . LEU A 186 ? 0.14230 0.25000 0.13370 -0.00200 -0.01610 0.02040  190 LEU A CD1 
2751 C CD2 . LEU A 186 ? 0.12690 0.22780 0.15000 0.00690  0.00720  0.03160  190 LEU A CD2 
2763 N N   A GLN A 187 ? 0.13920 0.20800 0.15510 0.00200  0.00730  0.01970  191 GLN A N   
2764 N N   C GLN A 187 ? 0.12950 0.20980 0.14580 0.00240  0.00310  0.02620  191 GLN A N   
2765 C CA  A GLN A 187 ? 0.15730 0.20780 0.16600 -0.00940 0.00950  0.01790  191 GLN A CA  
2766 C CA  C GLN A 187 ? 0.14070 0.21070 0.14400 -0.00880 0.00080  0.03160  191 GLN A CA  
2767 C C   A GLN A 187 ? 0.16350 0.20410 0.15660 -0.01350 0.01790  0.02570  191 GLN A C   
2768 C C   C GLN A 187 ? 0.15740 0.20810 0.13910 -0.01740 0.01760  0.03550  191 GLN A C   
2769 O O   A GLN A 187 ? 0.16330 0.20500 0.16280 -0.02190 0.01890  0.02400  191 GLN A O   
2770 O O   C GLN A 187 ? 0.15270 0.21380 0.15250 -0.03050 0.01910  0.02800  191 GLN A O   
2771 C CB  A GLN A 187 ? 0.17680 0.21740 0.17520 -0.01360 0.01490  0.01080  191 GLN A CB  
2772 C CB  C GLN A 187 ? 0.15420 0.22050 0.13430 -0.00740 0.00270  0.03520  191 GLN A CB  
2773 C CG  A GLN A 187 ? 0.20580 0.23040 0.19200 -0.02010 0.02020  0.00870  191 GLN A CG  
2774 C CG  C GLN A 187 ? 0.17560 0.22780 0.13020 -0.01260 0.00600  0.04830  191 GLN A CG  
2775 C CD  A GLN A 187 ? 0.23550 0.24570 0.22300 -0.03650 0.01920  0.01170  191 GLN A CD  
2776 C CD  C GLN A 187 ? 0.19340 0.24290 0.15230 -0.02390 0.00630  0.06490  191 GLN A CD  
2777 O OE1 A GLN A 187 ? 0.26540 0.26430 0.23410 -0.04340 0.02700  0.02100  191 GLN A OE1 
2778 O OE1 C GLN A 187 ? 0.20920 0.25650 0.18860 -0.01350 0.01320  0.06830  191 GLN A OE1 
2779 N NE2 A GLN A 187 ? 0.24150 0.24560 0.24540 -0.03300 0.02700  0.00820  191 GLN A NE2 
2780 N NE2 C GLN A 187 ? 0.22100 0.25440 0.17720 -0.02100 -0.00470 0.04350  191 GLN A NE2 
2797 N N   . LYS A 188 ? 0.15650 0.19680 0.16440 -0.00530 0.01420  0.01900  192 LYS A N   
2798 C CA  . LYS A 188 ? 0.14240 0.20890 0.16700 0.00410  0.00820  0.01650  192 LYS A CA  
2799 C C   . LYS A 188 ? 0.14870 0.21300 0.17320 -0.00740 0.01030  0.01200  192 LYS A C   
2800 O O   . LYS A 188 ? 0.18230 0.20550 0.18720 -0.01010 0.02060  0.01710  192 LYS A O   
2801 C CB  . LYS A 188 ? 0.14570 0.23100 0.19480 0.01180  -0.00880 0.03420  192 LYS A CB  
2802 C CG  . LYS A 188 ? 0.14330 0.24620 0.20080 0.02810  0.00290  0.03450  192 LYS A CG  
2803 C CD  . LYS A 188 ? 0.13530 0.25660 0.19970 0.01590  0.00500  0.03920  192 LYS A CD  
2804 C CE  . LYS A 188 ? 0.15350 0.27610 0.20080 0.02320  0.00780  0.03080  192 LYS A CE  
2805 N NZ  . LYS A 188 ? 0.17150 0.28690 0.19580 0.03190  0.01160  0.04480  192 LYS A NZ  
2820 N N   . LEU A 189 ? 0.14570 0.21340 0.15920 0.00070  0.01400  -0.00040 193 LEU A N   
2821 C CA  . LEU A 189 ? 0.15080 0.21790 0.17170 -0.01660 0.00720  0.02290  193 LEU A CA  
2822 C C   . LEU A 189 ? 0.14160 0.22440 0.16260 -0.02760 -0.00870 0.00500  193 LEU A C   
2823 O O   . LEU A 189 ? 0.16370 0.26600 0.20580 -0.03830 -0.00230 -0.02680 193 LEU A O   
2824 C CB  . LEU A 189 ? 0.15110 0.20760 0.15790 -0.01860 -0.00280 0.00370  193 LEU A CB  
2825 C CG  . LEU A 189 ? 0.14960 0.22010 0.16150 -0.00730 0.00090  0.00110  193 LEU A CG  
2826 C CD1 . LEU A 189 ? 0.13920 0.23150 0.17820 -0.00830 0.00210  0.00290  193 LEU A CD1 
2827 C CD2 . LEU A 189 ? 0.17830 0.23180 0.17420 -0.01910 0.01030  -0.00520 193 LEU A CD2 
2839 N N   . THR A 190 ? 0.16310 0.21630 0.15140 -0.03760 0.01590  -0.00130 194 THR A N   
2840 C CA  . THR A 190 ? 0.15140 0.21770 0.17590 -0.04520 0.00160  -0.00200 194 THR A CA  
2841 C C   . THR A 190 ? 0.15970 0.22860 0.20780 -0.02930 0.00090  0.02880  194 THR A C   
2842 O O   . THR A 190 ? 0.17540 0.25460 0.24170 -0.04680 0.00170  0.05510  194 THR A O   
2843 C CB  . THR A 190 ? 0.12680 0.23650 0.17030 -0.03530 0.00010  0.00440  194 THR A CB  
2844 O OG1 . THR A 190 ? 0.13770 0.24370 0.17360 -0.02680 -0.00520 0.01170  194 THR A OG1 
2845 C CG2 . THR A 190 ? 0.13660 0.25190 0.16550 -0.02540 0.02030  -0.00280 194 THR A CG2 
2853 N N   . LEU A 191 ? 0.17190 0.21170 0.19370 -0.04100 0.00290  0.04950  195 LEU A N   
2854 C CA  . LEU A 191 ? 0.21000 0.22010 0.21070 -0.04110 0.01270  0.04230  195 LEU A CA  
2855 C C   . LEU A 191 ? 0.22820 0.22510 0.22930 -0.03160 0.01310  0.04680  195 LEU A C   
2856 O O   . LEU A 191 ? 0.23080 0.22420 0.27870 -0.02930 0.03880  0.05680  195 LEU A O   
2857 C CB  . LEU A 191 ? 0.19780 0.22110 0.21540 -0.03100 0.03230  0.03000  195 LEU A CB  
2858 C CG  . LEU A 191 ? 0.19360 0.23760 0.20330 -0.02440 0.01990  0.02250  195 LEU A CG  
2859 C CD1 . LEU A 191 ? 0.19750 0.24150 0.23150 -0.04280 0.02420  0.02350  195 LEU A CD1 
2860 C CD2 . LEU A 191 ? 0.19460 0.25770 0.20700 -0.01370 0.03280  0.00500  195 LEU A CD2 
2872 N N   . GLY A 192 ? 0.21920 0.23080 0.20400 -0.02660 0.02430  0.04360  196 GLY A N   
2873 C CA  . GLY A 192 ? 0.23970 0.25850 0.21850 -0.01210 0.02610  0.02450  196 GLY A CA  
2874 C C   . GLY A 192 ? 0.25310 0.27180 0.24070 -0.00570 0.01990  0.00530  196 GLY A C   
2875 O O   . GLY A 192 ? 0.25650 0.28220 0.24710 -0.00830 0.00940  -0.02290 196 GLY A O   
2879 N N   . SER A 193 ? 0.25220 0.27240 0.25280 -0.00060 0.01190  -0.00130 197 SER A N   
2880 C CA  . SER A 193 ? 0.27810 0.26620 0.27830 0.02810  0.00470  0.00310  197 SER A CA  
2881 C C   . SER A 193 ? 0.26290 0.26210 0.24360 0.03960  -0.01130 -0.01210 197 SER A C   
2882 O O   . SER A 193 ? 0.28290 0.25700 0.27890 0.05040  -0.00400 -0.02190 197 SER A O   
2883 C CB  . SER A 193 ? 0.32950 0.28130 0.32630 0.03410  -0.00430 0.00090  197 SER A CB  
2884 O OG  . SER A 193 ? 0.37980 0.30950 0.36410 0.04390  -0.00580 0.00270  197 SER A OG  
2890 N N   . ALA A 194 ? 0.23520 0.26560 0.21870 0.03850  -0.00880 0.00490  198 ALA A N   
2891 C CA  . ALA A 194 ? 0.23470 0.27180 0.20460 0.04530  0.01580  -0.00690 198 ALA A CA  
2892 C C   . ALA A 194 ? 0.25460 0.28420 0.21460 0.03060  0.02020  -0.01880 198 ALA A C   
2893 O O   . ALA A 194 ? 0.27680 0.31560 0.20500 0.02050  0.01020  -0.01090 198 ALA A O   
2894 C CB  . ALA A 194 ? 0.21830 0.26570 0.20910 0.05180  0.02500  0.01620  198 ALA A CB  
2900 N N   . LEU A 195 ? 0.24150 0.27720 0.20600 0.01790  0.01740  -0.01820 199 LEU A N   
2901 C CA  . LEU A 195 ? 0.27030 0.27280 0.22260 0.00720  0.00340  -0.02130 199 LEU A CA  
2902 C C   . LEU A 195 ? 0.28610 0.27230 0.25900 0.00270  -0.01640 -0.00630 199 LEU A C   
2903 O O   . LEU A 195 ? 0.31220 0.27960 0.25050 -0.00500 -0.01610 0.01120  199 LEU A O   
2904 C CB  . LEU A 195 ? 0.27830 0.27570 0.19130 0.00610  -0.00760 -0.01690 199 LEU A CB  
2905 C CG  . LEU A 195 ? 0.26900 0.28530 0.17350 0.00690  -0.01650 -0.00540 199 LEU A CG  
2906 C CD1 . LEU A 195 ? 0.26720 0.29740 0.16310 0.00170  0.00070  -0.00090 199 LEU A CD1 
2907 C CD2 . LEU A 195 ? 0.27330 0.29340 0.20740 0.02360  0.00160  -0.00740 199 LEU A CD2 
2919 N N   . ALA A 196 ? 0.29260 0.26320 0.27140 0.00590  -0.02710 -0.00980 200 ALA A N   
2920 C CA  . ALA A 196 ? 0.31030 0.26380 0.30730 -0.00090 -0.03030 -0.00920 200 ALA A CA  
2921 C C   . ALA A 196 ? 0.29480 0.26090 0.29780 -0.01870 -0.02170 -0.02430 200 ALA A C   
2922 O O   . ALA A 196 ? 0.27930 0.25210 0.27750 -0.02290 -0.03420 -0.02130 200 ALA A O   
2923 C CB  . ALA A 196 ? 0.34290 0.27110 0.32950 -0.00470 -0.03830 0.00320  200 ALA A CB  
2929 N N   . ALA A 197 ? 0.31300 0.25880 0.31530 -0.01390 -0.01110 -0.01930 201 ALA A N   
2930 C CA  . ALA A 197 ? 0.30510 0.26160 0.34430 -0.03220 0.00000  0.00160  201 ALA A CA  
2931 C C   . ALA A 197 ? 0.30250 0.26190 0.33770 -0.03420 -0.01760 -0.00490 201 ALA A C   
2932 O O   . ALA A 197 ? 0.28750 0.24770 0.31600 -0.03770 -0.03610 -0.00420 201 ALA A O   
2933 C CB  . ALA A 197 ? 0.33400 0.27180 0.37460 -0.03390 0.01770  0.00930  201 ALA A CB  
2939 N N   . PRO A 198 ? 0.30480 0.26030 0.34630 -0.04280 -0.02500 -0.03440 202 PRO A N   
2940 C CA  . PRO A 198 ? 0.29080 0.27070 0.32500 -0.03860 -0.01610 -0.05220 202 PRO A CA  
2941 C C   . PRO A 198 ? 0.24960 0.27140 0.27840 -0.03040 -0.00910 -0.04640 202 PRO A C   
2942 O O   . PRO A 198 ? 0.23760 0.28360 0.25320 -0.03020 -0.02030 -0.03210 202 PRO A O   
2943 C CB  . PRO A 198 ? 0.32080 0.27840 0.34730 -0.04530 -0.02700 -0.05330 202 PRO A CB  
2944 C CG  . PRO A 198 ? 0.33770 0.28720 0.36360 -0.05380 -0.02740 -0.05540 202 PRO A CG  
2945 C CD  . PRO A 198 ? 0.32180 0.27390 0.35540 -0.05930 -0.03480 -0.05090 202 PRO A CD  
2953 N N   . GLN A 199 ? 0.22290 0.26650 0.24780 -0.02220 -0.00930 -0.03400 203 GLN A N   
2954 C CA  . GLN A 199 ? 0.24980 0.25380 0.23780 -0.01230 -0.01050 -0.03470 203 GLN A CA  
2955 C C   . GLN A 199 ? 0.23060 0.22650 0.21980 -0.02530 -0.00400 -0.01610 203 GLN A C   
2956 O O   . GLN A 199 ? 0.19200 0.20410 0.21070 -0.02460 -0.00720 -0.00320 203 GLN A O   
2957 C CB  . GLN A 199 ? 0.25840 0.26200 0.21000 0.02900  -0.02490 -0.04260 203 GLN A CB  
2958 C CG  . GLN A 199 ? 0.28540 0.27270 0.22160 0.03550  -0.04920 -0.05990 203 GLN A CG  
2959 C CD  . GLN A 199 ? 0.32640 0.29660 0.25130 0.03040  -0.07290 -0.07060 203 GLN A CD  
2960 O OE1 . GLN A 199 ? 0.33190 0.29750 0.27910 0.02710  -0.04640 -0.06870 203 GLN A OE1 
2961 N NE2 . GLN A 199 ? 0.37310 0.31620 0.28640 0.03200  -0.09120 -0.07050 203 GLN A NE2 
2970 N N   A ARG A 200 ? 0.22950 0.22710 0.21500 -0.02690 -0.01410 -0.00880 204 ARG A N   
2971 N N   B ARG A 200 ? 0.22710 0.22110 0.21500 -0.02720 -0.00730 -0.00770 204 ARG A N   
2972 C CA  A ARG A 200 ? 0.22450 0.23630 0.21980 -0.02270 -0.00690 -0.01080 204 ARG A CA  
2973 C CA  B ARG A 200 ? 0.22350 0.22220 0.21470 -0.02680 -0.00480 -0.00360 204 ARG A CA  
2974 C C   A ARG A 200 ? 0.20570 0.24290 0.20090 -0.03340 -0.01060 -0.00830 204 ARG A C   
2975 C C   B ARG A 200 ? 0.21420 0.23000 0.20380 -0.03400 -0.00630 -0.00240 204 ARG A C   
2976 O O   A ARG A 200 ? 0.17960 0.24400 0.16400 -0.03940 -0.01280 -0.00150 204 ARG A O   
2977 O O   B ARG A 200 ? 0.20300 0.22840 0.18680 -0.03510 -0.00900 0.00450  204 ARG A O   
2978 C CB  A ARG A 200 ? 0.24450 0.24970 0.23920 -0.01280 -0.01340 -0.01650 204 ARG A CB  
2979 C CB  B ARG A 200 ? 0.23430 0.22290 0.22420 -0.02020 -0.01000 -0.00250 204 ARG A CB  
2980 C CG  A ARG A 200 ? 0.26690 0.25660 0.24720 -0.01830 -0.02040 -0.01170 204 ARG A CG  
2981 C CG  B ARG A 200 ? 0.24140 0.21900 0.22330 -0.02570 -0.01540 0.00530  204 ARG A CG  
2982 C CD  A ARG A 200 ? 0.29260 0.27120 0.27580 -0.02490 -0.02520 0.00050  204 ARG A CD  
2983 C CD  B ARG A 200 ? 0.24970 0.21940 0.23300 -0.03170 -0.01930 0.01390  204 ARG A CD  
2984 N NE  A ARG A 200 ? 0.32180 0.28490 0.31700 -0.03060 -0.03630 0.00260  204 ARG A NE  
2985 N NE  B ARG A 200 ? 0.25610 0.22570 0.24330 -0.03470 -0.01700 0.01480  204 ARG A NE  
2986 C CZ  A ARG A 200 ? 0.33200 0.29440 0.34410 -0.02910 -0.02930 0.00720  204 ARG A CZ  
2987 C CZ  B ARG A 200 ? 0.25800 0.23180 0.26980 -0.02330 -0.00870 0.01580  204 ARG A CZ  
2988 N NH1 A ARG A 200 ? 0.35380 0.29820 0.36980 -0.02140 -0.02200 0.01060  204 ARG A NH1 
2989 N NH1 B ARG A 200 ? 0.26120 0.23540 0.28080 -0.02630 -0.00610 0.01530  204 ARG A NH1 
2990 N NH2 A ARG A 200 ? 0.32920 0.30460 0.35830 -0.02670 -0.01110 0.00600  204 ARG A NH2 
2991 N NH2 B ARG A 200 ? 0.26040 0.23410 0.28060 -0.02770 0.00240  0.03130  204 ARG A NH2 
3018 N N   . GLN A 201 ? 0.22040 0.23540 0.20270 -0.04080 -0.00190 -0.00570 205 GLN A N   
3019 C CA  . GLN A 201 ? 0.22260 0.25360 0.23110 -0.05250 -0.00760 0.00540  205 GLN A CA  
3020 C C   . GLN A 201 ? 0.18500 0.25430 0.20520 -0.05780 -0.01030 -0.01820 205 GLN A C   
3021 O O   . GLN A 201 ? 0.19350 0.25960 0.20250 -0.05210 0.00170  -0.00230 205 GLN A O   
3022 C CB  . GLN A 201 ? 0.22730 0.26920 0.27410 -0.04580 0.00100  0.02050  205 GLN A CB  
3023 C CG  . GLN A 201 ? 0.24740 0.29580 0.30310 -0.04330 0.00820  0.03280  205 GLN A CG  
3024 C CD  . GLN A 201 ? 0.26660 0.31650 0.30580 -0.03940 0.01700  0.05210  205 GLN A CD  
3025 O OE1 . GLN A 201 ? 0.27020 0.33750 0.31320 -0.04330 0.03160  0.06180  205 GLN A OE1 
3026 N NE2 . GLN A 201 ? 0.27170 0.31390 0.27980 -0.03910 0.01750  0.05500  205 GLN A NE2 
3036 N N   . GLN A 202 ? 0.16400 0.24900 0.20920 -0.06180 -0.01000 -0.04350 206 GLN A N   
3037 C CA  . GLN A 202 ? 0.18830 0.25880 0.21100 -0.02990 -0.00280 -0.03770 206 GLN A CA  
3038 C C   . GLN A 202 ? 0.17390 0.25860 0.18430 -0.02550 0.00000  -0.01810 206 GLN A C   
3039 O O   . GLN A 202 ? 0.17980 0.26550 0.16770 -0.03840 -0.00330 -0.01050 206 GLN A O   
3040 C CB  . GLN A 202 ? 0.22010 0.26710 0.20520 -0.03480 -0.00810 -0.03820 206 GLN A CB  
3041 C CG  . GLN A 202 ? 0.23650 0.28590 0.19720 -0.02900 -0.01060 -0.02830 206 GLN A CG  
3042 C CD  . GLN A 202 ? 0.25280 0.30530 0.22510 -0.03790 -0.03020 -0.04270 206 GLN A CD  
3043 O OE1 . GLN A 202 ? 0.27150 0.33120 0.23390 -0.03670 -0.07070 -0.04690 206 GLN A OE1 
3044 N NE2 . GLN A 202 ? 0.23370 0.29380 0.22020 -0.02610 -0.00750 -0.03070 206 GLN A NE2 
3053 N N   . PHE A 203 ? 0.15100 0.24660 0.18550 -0.02530 0.00650  -0.01690 207 PHE A N   
3054 C CA  . PHE A 203 ? 0.12910 0.24120 0.17440 -0.01910 -0.00340 -0.02270 207 PHE A CA  
3055 C C   . PHE A 203 ? 0.13720 0.24880 0.16570 -0.02400 -0.00920 -0.01310 207 PHE A C   
3056 O O   . PHE A 203 ? 0.14290 0.24380 0.16800 -0.02670 -0.00540 0.00240  207 PHE A O   
3057 C CB  . PHE A 203 ? 0.15000 0.24830 0.17070 -0.01810 0.02870  0.00780  207 PHE A CB  
3058 C CG  . PHE A 203 ? 0.13780 0.25010 0.16280 -0.00890 0.01270  0.01340  207 PHE A CG  
3059 C CD1 . PHE A 203 ? 0.16140 0.24820 0.17900 -0.01840 -0.00830 0.02150  207 PHE A CD1 
3060 C CD2 . PHE A 203 ? 0.16150 0.25790 0.15190 0.00380  0.00810  -0.00920 207 PHE A CD2 
3061 C CE1 . PHE A 203 ? 0.15240 0.25260 0.16950 -0.01980 0.00030  0.01250  207 PHE A CE1 
3062 C CE2 . PHE A 203 ? 0.15630 0.25530 0.14000 -0.00170 0.00950  0.00110  207 PHE A CE2 
3063 C CZ  . PHE A 203 ? 0.13230 0.25350 0.15050 -0.01620 0.01780  0.00020  207 PHE A CZ  
3073 N N   . VAL A 204 ? 0.15240 0.25160 0.16370 -0.02090 0.00350  -0.00840 208 VAL A N   
3074 C CA  . VAL A 204 ? 0.15820 0.26940 0.15910 -0.01330 -0.00480 -0.00780 208 VAL A CA  
3075 C C   . VAL A 204 ? 0.13750 0.27270 0.14490 -0.03780 0.01680  -0.01770 208 VAL A C   
3076 O O   . VAL A 204 ? 0.14410 0.27680 0.15000 -0.02960 0.01290  -0.00500 208 VAL A O   
3077 C CB  . VAL A 204 ? 0.16900 0.27500 0.15730 -0.01750 -0.00350 0.00420  208 VAL A CB  
3078 C CG1 . VAL A 204 ? 0.16750 0.28280 0.17620 -0.02280 -0.00060 0.01240  208 VAL A CG1 
3079 C CG2 . VAL A 204 ? 0.15520 0.27890 0.17620 -0.01130 0.00830  0.01060  208 VAL A CG2 
3089 N N   . ASP A 205 ? 0.15880 0.28670 0.15820 -0.05940 0.00400  -0.02990 209 ASP A N   
3090 C CA  . ASP A 205 ? 0.15110 0.29320 0.18340 -0.04270 -0.00790 -0.02760 209 ASP A CA  
3091 C C   . ASP A 205 ? 0.13460 0.28680 0.16000 -0.02340 -0.00240 -0.03010 209 ASP A C   
3092 O O   . ASP A 205 ? 0.12900 0.28410 0.18440 -0.02270 0.00500  -0.02340 209 ASP A O   
3093 C CB  . ASP A 205 ? 0.17860 0.30130 0.21640 -0.05720 -0.02160 -0.01740 209 ASP A CB  
3094 C CG  . ASP A 205 ? 0.19620 0.31860 0.27690 -0.06640 -0.02690 -0.01230 209 ASP A CG  
3095 O OD1 . ASP A 205 ? 0.21930 0.33760 0.32360 -0.05560 -0.02480 0.02420  209 ASP A OD1 
3096 O OD2 . ASP A 205 ? 0.21870 0.32300 0.32140 -0.08860 -0.00430 -0.02630 209 ASP A OD2 
3101 N N   . TRP A 206 ? 0.14640 0.27730 0.13130 0.00180  -0.01120 0.00660  210 TRP A N   
3102 C CA  . TRP A 206 ? 0.14320 0.26280 0.13090 -0.00500 -0.00380 0.02640  210 TRP A CA  
3103 C C   . TRP A 206 ? 0.12130 0.25270 0.13470 0.00680  -0.00320 0.03820  210 TRP A C   
3104 O O   . TRP A 206 ? 0.13870 0.27310 0.13660 -0.01310 -0.00750 0.02120  210 TRP A O   
3105 C CB  . TRP A 206 ? 0.18400 0.27170 0.13400 -0.02410 -0.01170 0.00130  210 TRP A CB  
3106 C CG  . TRP A 206 ? 0.19900 0.27370 0.13670 -0.03310 -0.01280 0.00150  210 TRP A CG  
3107 C CD1 . TRP A 206 ? 0.20920 0.28430 0.13690 -0.02770 -0.00080 -0.00640 210 TRP A CD1 
3108 C CD2 . TRP A 206 ? 0.20060 0.25800 0.12950 -0.02500 -0.01120 -0.00730 210 TRP A CD2 
3109 N NE1 . TRP A 206 ? 0.21110 0.27900 0.13760 -0.01450 -0.02880 -0.02270 210 TRP A NE1 
3110 C CE2 . TRP A 206 ? 0.21940 0.26070 0.14230 -0.02230 0.00950  -0.02050 210 TRP A CE2 
3111 C CE3 . TRP A 206 ? 0.18770 0.24450 0.13900 -0.01270 0.00330  -0.01580 210 TRP A CE3 
3112 C CZ2 . TRP A 206 ? 0.24240 0.24890 0.13730 -0.02640 0.00490  -0.00790 210 TRP A CZ2 
3113 C CZ3 . TRP A 206 ? 0.21830 0.24060 0.15520 -0.03260 0.01130  -0.02240 210 TRP A CZ3 
3114 C CH2 . TRP A 206 ? 0.23540 0.24410 0.16330 -0.04200 0.02370  -0.01160 210 TRP A CH2 
3125 N N   . LEU A 207 ? 0.13580 0.23880 0.13360 -0.00670 -0.00100 0.01450  211 LEU A N   
3126 C CA  . LEU A 207 ? 0.13000 0.23890 0.13440 -0.01180 0.00960  -0.00050 211 LEU A CA  
3127 C C   . LEU A 207 ? 0.11020 0.24130 0.13380 -0.00900 0.01420  0.00350  211 LEU A C   
3128 O O   . LEU A 207 ? 0.12280 0.24640 0.13670 0.01190  0.00640  -0.02050 211 LEU A O   
3129 C CB  . LEU A 207 ? 0.12600 0.25190 0.13630 -0.02560 0.02200  0.00440  211 LEU A CB  
3130 C CG  . LEU A 207 ? 0.13360 0.25920 0.13590 -0.02150 0.00370  0.00280  211 LEU A CG  
3131 C CD1 . LEU A 207 ? 0.14380 0.26590 0.14930 -0.00460 0.00460  -0.00060 211 LEU A CD1 
3132 C CD2 . LEU A 207 ? 0.12090 0.26880 0.12200 -0.02020 -0.00440 -0.01120 211 LEU A CD2 
3144 N N   . LYS A 208 ? 0.13180 0.24170 0.13290 -0.03430 0.00710  0.00750  212 LYS A N   
3145 C CA  . LYS A 208 ? 0.13590 0.24800 0.16220 -0.02410 0.01850  0.01400  212 LYS A CA  
3146 C C   . LYS A 208 ? 0.13630 0.26870 0.16120 -0.00790 -0.00780 0.00340  212 LYS A C   
3147 O O   . LYS A 208 ? 0.15830 0.27010 0.16900 0.00560  0.00740  -0.00200 212 LYS A O   
3148 C CB  . LYS A 208 ? 0.15870 0.24050 0.18730 -0.02470 0.01480  0.02510  212 LYS A CB  
3149 C CG  . LYS A 208 ? 0.22090 0.23380 0.22150 -0.03830 0.05310  0.05460  212 LYS A CG  
3150 C CD  . LYS A 208 ? 0.29770 0.25430 0.28220 -0.05060 0.07320  0.05060  212 LYS A CD  
3151 C CE  . LYS A 208 ? 0.33550 0.27820 0.34750 -0.06220 0.08610  0.02820  212 LYS A CE  
3152 N NZ  . LYS A 208 ? 0.35290 0.28520 0.37400 -0.07360 0.09720  0.01250  212 LYS A NZ  
3166 N N   . GLY A 209 ? 0.12040 0.27940 0.16160 -0.00190 -0.02020 -0.00120 213 GLY A N   
3167 C CA  . GLY A 209 ? 0.12220 0.27680 0.17250 -0.00420 -0.01720 -0.00870 213 GLY A CA  
3168 C C   . GLY A 209 ? 0.13740 0.26140 0.15200 -0.00570 -0.01180 -0.00530 213 GLY A C   
3169 O O   . GLY A 209 ? 0.15810 0.26630 0.16440 0.00560  -0.03080 0.00780  213 GLY A O   
3173 N N   . ASN A 210 ? 0.11210 0.25740 0.14580 -0.01900 -0.00650 -0.00400 214 ASN A N   
3174 C CA  . ASN A 210 ? 0.12210 0.26850 0.13370 -0.01610 -0.02100 -0.00430 214 ASN A CA  
3175 C C   . ASN A 210 ? 0.11940 0.27680 0.14720 -0.01230 -0.01550 -0.00300 214 ASN A C   
3176 O O   . ASN A 210 ? 0.12770 0.28060 0.15230 0.00400  0.00020  0.01300  214 ASN A O   
3177 C CB  . ASN A 210 ? 0.11640 0.27040 0.14520 -0.01610 -0.01310 0.00040  214 ASN A CB  
3178 C CG  . ASN A 210 ? 0.12780 0.26580 0.13310 -0.02030 0.00360  0.00450  214 ASN A CG  
3179 O OD1 . ASN A 210 ? 0.13810 0.27090 0.13550 -0.02830 -0.00830 0.03260  214 ASN A OD1 
3180 N ND2 . ASN A 210 ? 0.15040 0.27420 0.12760 -0.00190 -0.01610 -0.00290 214 ASN A ND2 
3187 N N   . THR A 211 ? 0.12070 0.28120 0.14090 -0.01160 -0.01570 0.01630  215 THR A N   
3188 C CA  . THR A 211 ? 0.12140 0.27820 0.14270 -0.01430 -0.00980 0.03810  215 THR A CA  
3189 C C   . THR A 211 ? 0.12450 0.27940 0.13660 -0.00710 0.00770  0.02500  215 THR A C   
3190 O O   . THR A 211 ? 0.12410 0.26770 0.17270 0.01560  -0.00980 0.00090  215 THR A O   
3191 C CB  . THR A 211 ? 0.12300 0.27280 0.16270 -0.00670 -0.02050 0.02600  215 THR A CB  
3192 O OG1 . THR A 211 ? 0.14780 0.27130 0.15460 0.01440  -0.01130 0.03420  215 THR A OG1 
3193 C CG2 . THR A 211 ? 0.14340 0.27630 0.18500 -0.01730 -0.01930 0.01600  215 THR A CG2 
3201 N N   . THR A 212 ? 0.13520 0.27790 0.13520 -0.01240 -0.02150 0.02790  216 THR A N   
3202 C CA  . THR A 212 ? 0.13090 0.28470 0.14240 -0.00160 -0.01040 0.01380  216 THR A CA  
3203 C C   . THR A 212 ? 0.15540 0.27090 0.13290 0.00430  -0.00840 -0.00140 216 THR A C   
3204 O O   . THR A 212 ? 0.16670 0.26000 0.13600 0.00190  0.00350  0.00280  216 THR A O   
3205 C CB  . THR A 212 ? 0.12430 0.29280 0.13950 -0.00950 -0.00120 0.00880  216 THR A CB  
3206 O OG1 . THR A 212 ? 0.13880 0.30620 0.16400 -0.00570 -0.01220 -0.00400 216 THR A OG1 
3207 C CG2 . THR A 212 ? 0.13130 0.30630 0.16950 -0.01820 -0.00220 0.00890  216 THR A CG2 
3215 N N   . GLY A 213 ? 0.14690 0.25650 0.13690 0.02140  0.00410  0.01160  217 GLY A N   
3216 C CA  . GLY A 213 ? 0.13380 0.25870 0.13370 0.00340  -0.00350 0.01020  217 GLY A CA  
3217 C C   . GLY A 213 ? 0.11970 0.26110 0.14710 0.00440  -0.00880 0.00040  217 GLY A C   
3218 O O   . GLY A 213 ? 0.13190 0.25450 0.14750 0.01350  -0.00270 0.01000  217 GLY A O   
3222 N N   . ASN A 214 ? 0.13190 0.27220 0.14560 -0.00490 -0.00870 0.00630  218 ASN A N   
3223 C CA  . ASN A 214 ? 0.12150 0.28560 0.16830 -0.00090 0.01580  0.01210  218 ASN A CA  
3224 C C   . ASN A 214 ? 0.12890 0.29240 0.15860 0.00180  0.02710  0.01060  218 ASN A C   
3225 O O   . ASN A 214 ? 0.14480 0.31860 0.15820 -0.00720 0.02920  -0.00530 218 ASN A O   
3226 C CB  . ASN A 214 ? 0.12830 0.30570 0.18480 0.00880  -0.00220 0.00490  218 ASN A CB  
3227 C CG  . ASN A 214 ? 0.16910 0.32650 0.23530 -0.00820 -0.02510 -0.01070 218 ASN A CG  
3228 O OD1 . ASN A 214 ? 0.15570 0.33950 0.25740 -0.02960 -0.02460 -0.05450 218 ASN A OD1 
3229 N ND2 . ASN A 214 ? 0.22810 0.34720 0.28610 -0.02030 -0.04530 -0.01230 218 ASN A ND2 
3236 N N   . HIS A 215 ? 0.13580 0.26120 0.12560 0.02420  0.01750  0.01380  219 HIS A N   
3237 C CA  . HIS A 215 ? 0.15170 0.26150 0.13080 0.02170  0.01780  0.02700  219 HIS A CA  
3238 C C   . HIS A 215 ? 0.14600 0.25610 0.14710 0.01180  0.00900  0.00620  219 HIS A C   
3239 O O   . HIS A 215 ? 0.16000 0.25660 0.15480 0.01230  0.01290  0.00940  219 HIS A O   
3240 C CB  . HIS A 215 ? 0.16660 0.28520 0.16620 0.03290  -0.00160 0.03410  219 HIS A CB  
3241 C CG  . HIS A 215 ? 0.21190 0.31710 0.23520 0.05500  -0.01190 0.04320  219 HIS A CG  
3242 N ND1 . HIS A 215 ? 0.20900 0.33620 0.29770 0.07180  -0.02650 0.05500  219 HIS A ND1 
3243 C CD2 . HIS A 215 ? 0.25670 0.34270 0.27260 0.05640  -0.01570 0.03810  219 HIS A CD2 
3244 C CE1 . HIS A 215 ? 0.24040 0.34850 0.31820 0.06240  -0.02950 0.05170  219 HIS A CE1 
3245 N NE2 . HIS A 215 ? 0.27600 0.35400 0.30730 0.06610  -0.03200 0.03890  219 HIS A NE2 
3253 N N   . ARG A 216 ? 0.11210 0.25930 0.14780 0.00220  0.01020  -0.01110 220 ARG A N   
3254 C CA  . ARG A 216 ? 0.11460 0.24810 0.13700 0.02350  0.00370  -0.01130 220 ARG A CA  
3255 C C   . ARG A 216 ? 0.10380 0.24740 0.13450 -0.00010 0.00700  0.00190  220 ARG A C   
3256 O O   . ARG A 216 ? 0.12290 0.25800 0.13470 -0.00910 0.02040  -0.00590 220 ARG A O   
3257 C CB  . ARG A 216 ? 0.10810 0.23900 0.13430 0.02860  0.01050  -0.00140 220 ARG A CB  
3258 C CG  . ARG A 216 ? 0.11740 0.25640 0.13150 0.03040  0.01440  -0.00060 220 ARG A CG  
3259 C CD  . ARG A 216 ? 0.12530 0.24570 0.12890 0.02390  0.00990  0.01580  220 ARG A CD  
3260 N NE  . ARG A 216 ? 0.12880 0.24630 0.12940 0.01490  0.01980  0.02160  220 ARG A NE  
3261 C CZ  . ARG A 216 ? 0.12760 0.25840 0.14030 0.01440  -0.00210 0.03330  220 ARG A CZ  
3262 N NH1 . ARG A 216 ? 0.12110 0.25900 0.12270 -0.00030 0.00720  0.03400  220 ARG A NH1 
3263 N NH2 . ARG A 216 ? 0.16330 0.26360 0.16930 0.00140  0.01470  0.02410  220 ARG A NH2 
3277 N N   . ILE A 217 ? 0.12620 0.22910 0.12970 0.00380  0.01630  0.01310  221 ILE A N   
3278 C CA  . ILE A 217 ? 0.13670 0.22500 0.11840 0.00480  0.02880  0.01210  221 ILE A CA  
3279 C C   . ILE A 217 ? 0.13820 0.23140 0.13720 0.00810  0.01570  0.03360  221 ILE A C   
3280 O O   . ILE A 217 ? 0.15760 0.23530 0.13560 -0.00150 0.03380  0.03080  221 ILE A O   
3281 C CB  . ILE A 217 ? 0.14390 0.20260 0.11270 -0.00130 0.00160  -0.00560 221 ILE A CB  
3282 C CG1 . ILE A 217 ? 0.14420 0.21140 0.11870 0.02770  0.00230  0.00180  221 ILE A CG1 
3283 C CG2 . ILE A 217 ? 0.15140 0.19060 0.13230 -0.01100 0.01130  0.00480  221 ILE A CG2 
3284 C CD1 . ILE A 217 ? 0.14700 0.22610 0.10060 0.02130  0.00860  0.01560  221 ILE A CD1 
3296 N N   . ARG A 218 ? 0.13950 0.23460 0.14520 -0.01180 0.02950  0.03630  222 ARG A N   
3297 C CA  . ARG A 218 ? 0.13820 0.25100 0.15900 -0.00530 0.02090  0.02020  222 ARG A CA  
3298 C C   . ARG A 218 ? 0.13790 0.26140 0.15970 0.00580  0.01390  0.01330  222 ARG A C   
3299 O O   . ARG A 218 ? 0.15910 0.27010 0.15670 0.00120  0.04730  0.02370  222 ARG A O   
3300 C CB  . ARG A 218 ? 0.12450 0.24590 0.17220 0.00150  0.01640  0.01980  222 ARG A CB  
3301 C CG  . ARG A 218 ? 0.16390 0.24860 0.16860 -0.01530 0.00810  0.02430  222 ARG A CG  
3302 C CD  . ARG A 218 ? 0.18070 0.26590 0.17130 -0.01720 0.00310  0.02000  222 ARG A CD  
3303 N NE  . ARG A 218 ? 0.14850 0.27120 0.16830 -0.02480 0.01200  0.02290  222 ARG A NE  
3304 C CZ  . ARG A 218 ? 0.17830 0.27640 0.18260 -0.03320 0.01640  0.02920  222 ARG A CZ  
3305 N NH1 . ARG A 218 ? 0.17240 0.28870 0.23480 -0.06800 0.01720  0.01080  222 ARG A NH1 
3306 N NH2 . ARG A 218 ? 0.20540 0.27120 0.16750 -0.02430 0.01880  0.01570  222 ARG A NH2 
3320 N N   . ALA A 219 ? 0.14200 0.25620 0.16190 0.01370  0.02960  0.00820  223 ALA A N   
3321 C CA  . ALA A 219 ? 0.17520 0.26870 0.16310 0.00350  0.02990  0.01590  223 ALA A CA  
3322 C C   . ALA A 219 ? 0.18750 0.28930 0.17560 0.02280  0.04180  0.01520  223 ALA A C   
3323 O O   . ALA A 219 ? 0.20920 0.31530 0.18100 0.05930  0.05120  -0.01410 223 ALA A O   
3324 C CB  . ALA A 219 ? 0.19850 0.26450 0.18670 -0.00310 0.01960  -0.01060 223 ALA A CB  
3330 N N   . ALA A 220 ? 0.19190 0.29200 0.16860 0.02830  0.02130  0.00540  224 ALA A N   
3331 C CA  . ALA A 220 ? 0.18990 0.30920 0.16110 0.04300  0.02490  0.01840  224 ALA A CA  
3332 C C   . ALA A 220 ? 0.17030 0.32720 0.16950 0.03740  0.03880  0.06550  224 ALA A C   
3333 O O   . ALA A 220 ? 0.22750 0.36030 0.17860 0.04130  0.02260  0.09460  224 ALA A O   
3334 C CB  . ALA A 220 ? 0.20860 0.32110 0.19580 0.00890  0.00720  0.01300  224 ALA A CB  
3340 N N   . VAL A 221 ? 0.15930 0.31850 0.21030 0.02770  0.03240  0.07030  225 VAL A N   
3341 C CA  . VAL A 221 ? 0.18520 0.32920 0.24680 0.02100  0.08580  0.07850  225 VAL A CA  
3342 C C   . VAL A 221 ? 0.18210 0.33860 0.25630 0.01540  0.08870  0.08560  225 VAL A C   
3343 O O   . VAL A 221 ? 0.17500 0.35310 0.28760 0.02610  0.06590  0.09580  225 VAL A O   
3344 C CB  . VAL A 221 ? 0.19880 0.32330 0.27870 0.01720  0.08420  0.06760  225 VAL A CB  
3345 C CG1 . VAL A 221 ? 0.23110 0.33640 0.31450 0.01340  0.06990  0.04890  225 VAL A CG1 
3346 C CG2 . VAL A 221 ? 0.20880 0.32350 0.30970 0.01670  0.06470  0.05310  225 VAL A CG2 
3356 N N   . PRO A 222 ? 0.19740 0.33460 0.24090 0.00400  0.08670  0.06900  226 PRO A N   
3357 C CA  . PRO A 222 ? 0.21150 0.33050 0.24160 -0.00630 0.07760  0.05530  226 PRO A CA  
3358 C C   . PRO A 222 ? 0.21910 0.35700 0.21030 0.01350  0.08410  0.06860  226 PRO A C   
3359 O O   . PRO A 222 ? 0.21000 0.35670 0.20220 0.02430  0.09780  0.04670  226 PRO A O   
3360 C CB  . PRO A 222 ? 0.20520 0.31460 0.24490 -0.01890 0.08290  0.04340  226 PRO A CB  
3361 C CG  . PRO A 222 ? 0.22280 0.31170 0.25560 -0.01230 0.06730  0.07110  226 PRO A CG  
3362 C CD  . PRO A 222 ? 0.21780 0.31940 0.25010 0.00520  0.07670  0.08100  226 PRO A CD  
3370 N N   . ALA A 223 ? 0.23270 0.37500 0.20300 0.04140  0.05160  0.07570  227 ALA A N   
3371 C CA  . ALA A 223 ? 0.23960 0.39320 0.21850 0.03880  0.05090  0.06490  227 ALA A CA  
3372 C C   . ALA A 223 ? 0.21060 0.39330 0.19200 0.02690  0.05390  0.03440  227 ALA A C   
3373 O O   . ALA A 223 ? 0.25370 0.42250 0.19240 0.02290  0.03270  0.03000  227 ALA A O   
3374 C CB  . ALA A 223 ? 0.27430 0.40020 0.23940 0.03760  0.00130  0.07590  227 ALA A CB  
3380 N N   . ASP A 224 ? 0.17360 0.37840 0.21050 0.00390  0.04480  0.03070  228 ASP A N   
3381 C CA  . ASP A 224 ? 0.15990 0.36260 0.18660 0.00230  0.00870  0.00520  228 ASP A CA  
3382 C C   . ASP A 224 ? 0.16110 0.35900 0.21250 -0.00550 0.00970  -0.00290 228 ASP A C   
3383 O O   . ASP A 224 ? 0.16490 0.37850 0.24960 -0.00040 0.00870  0.01490  228 ASP A O   
3384 C CB  . ASP A 224 ? 0.17370 0.35820 0.15020 0.00470  0.00620  -0.02660 228 ASP A CB  
3385 C CG  . ASP A 224 ? 0.18370 0.34150 0.15010 -0.02280 0.00950  -0.00930 228 ASP A CG  
3386 O OD1 . ASP A 224 ? 0.18110 0.32970 0.14190 -0.02770 0.01250  0.00160  228 ASP A OD1 
3387 O OD2 . ASP A 224 ? 0.21490 0.33620 0.16770 -0.05690 0.00170  -0.01140 228 ASP A OD2 
3392 N N   . TRP A 225 ? 0.15140 0.34880 0.18160 -0.00770 0.02610  -0.01170 229 TRP A N   
3393 C CA  . TRP A 225 ? 0.17050 0.34160 0.18060 -0.00130 0.03620  -0.01450 229 TRP A CA  
3394 C C   . TRP A 225 ? 0.21480 0.34480 0.18760 0.00880  0.02970  0.00150  229 TRP A C   
3395 O O   . TRP A 225 ? 0.27120 0.36750 0.19220 0.01510  0.02850  0.02010  229 TRP A O   
3396 C CB  . TRP A 225 ? 0.16440 0.32170 0.19670 -0.01730 0.03790  -0.01080 229 TRP A CB  
3397 C CG  . TRP A 225 ? 0.14750 0.30650 0.18320 -0.03140 0.04870  0.00550  229 TRP A CG  
3398 C CD1 . TRP A 225 ? 0.15790 0.30520 0.17490 -0.03770 0.03170  0.00340  229 TRP A CD1 
3399 C CD2 . TRP A 225 ? 0.13710 0.30480 0.21450 -0.02990 0.04440  -0.01900 229 TRP A CD2 
3400 N NE1 . TRP A 225 ? 0.15950 0.30340 0.18030 -0.04410 0.02720  -0.02560 229 TRP A NE1 
3401 C CE2 . TRP A 225 ? 0.14940 0.31070 0.19740 -0.03390 0.02080  -0.02530 229 TRP A CE2 
3402 C CE3 . TRP A 225 ? 0.14660 0.30990 0.26250 -0.04060 0.02000  -0.02970 229 TRP A CE3 
3403 C CZ2 . TRP A 225 ? 0.18830 0.32180 0.23240 -0.03720 0.01600  -0.04440 229 TRP A CZ2 
3404 C CZ3 . TRP A 225 ? 0.18620 0.31830 0.26960 -0.04300 0.03330  -0.04230 229 TRP A CZ3 
3405 C CH2 . TRP A 225 ? 0.18960 0.32750 0.25020 -0.02340 0.02260  -0.04790 229 TRP A CH2 
3416 N N   . ALA A 226 ? 0.16520 0.34010 0.18910 -0.00470 0.04840  -0.01650 230 ALA A N   
3417 C CA  . ALA A 226 ? 0.13850 0.32140 0.16360 -0.01810 0.03520  -0.00000 230 ALA A CA  
3418 C C   . ALA A 226 ? 0.14470 0.30850 0.14470 -0.00460 0.01240  0.01000  230 ALA A C   
3419 O O   . ALA A 226 ? 0.15190 0.30770 0.13980 -0.00120 0.01300  0.01150  230 ALA A O   
3420 C CB  . ALA A 226 ? 0.14550 0.32180 0.16560 -0.03230 0.01450  -0.00400 230 ALA A CB  
3426 N N   . VAL A 227 ? 0.13200 0.29810 0.14780 -0.00790 0.00270  0.01080  231 VAL A N   
3427 C CA  A VAL A 227 ? 0.15050 0.27850 0.14190 -0.01420 0.00710  0.01410  231 VAL A CA  
3428 C CA  B VAL A 227 ? 0.15720 0.27980 0.14610 -0.01210 0.01120  0.00430  231 VAL A CA  
3429 C C   . VAL A 227 ? 0.14000 0.27200 0.12180 -0.00410 0.01110  0.01660  231 VAL A C   
3430 O O   . VAL A 227 ? 0.15100 0.28950 0.14430 0.01050  -0.01430 0.01130  231 VAL A O   
3431 C CB  A VAL A 227 ? 0.16480 0.27110 0.17310 -0.00280 -0.01770 0.00060  231 VAL A CB  
3432 C CB  B VAL A 227 ? 0.18320 0.27250 0.18720 0.00260  0.00180  -0.02520 231 VAL A CB  
3433 C CG1 A VAL A 227 ? 0.16990 0.26210 0.16290 0.00670  -0.02540 0.00800  231 VAL A CG1 
3434 C CG1 B VAL A 227 ? 0.19610 0.28050 0.21380 0.00410  -0.00520 -0.03650 231 VAL A CG1 
3435 C CG2 A VAL A 227 ? 0.16840 0.28110 0.18840 -0.00320 -0.01620 -0.00400 231 VAL A CG2 
3436 C CG2 B VAL A 227 ? 0.19780 0.26640 0.18430 0.00570  0.00860  -0.02440 231 VAL A CG2 
3455 N N   . GLY A 228 ? 0.12340 0.26110 0.12930 -0.01850 0.02290  0.01050  232 GLY A N   
3456 C CA  . GLY A 228 ? 0.13200 0.25540 0.14320 -0.03870 0.01050  0.01850  232 GLY A CA  
3457 C C   . GLY A 228 ? 0.11350 0.23710 0.11580 -0.03890 0.02090  0.01540  232 GLY A C   
3458 O O   . GLY A 228 ? 0.13090 0.24690 0.13430 -0.03890 0.00310  0.02730  232 GLY A O   
3462 N N   . ASP A 229 ? 0.12040 0.23240 0.11140 -0.03050 -0.00310 0.00530  233 ASP A N   
3463 C CA  . ASP A 229 ? 0.11340 0.22840 0.10740 -0.02820 0.00730  0.01440  233 ASP A CA  
3464 C C   . ASP A 229 ? 0.11640 0.22600 0.12940 -0.03230 0.00090  0.00210  233 ASP A C   
3465 O O   . ASP A 229 ? 0.11190 0.23300 0.14190 -0.02480 -0.01160 0.00170  233 ASP A O   
3466 C CB  . ASP A 229 ? 0.13670 0.22630 0.11000 -0.02650 -0.00100 0.02280  233 ASP A CB  
3467 C CG  . ASP A 229 ? 0.11010 0.22900 0.12660 -0.01130 0.02030  0.00010  233 ASP A CG  
3468 O OD1 . ASP A 229 ? 0.10730 0.23380 0.13300 -0.00420 -0.00620 0.00320  233 ASP A OD1 
3469 O OD2 . ASP A 229 ? 0.11160 0.22740 0.13460 -0.01110 0.00250  0.01170  233 ASP A OD2 
3474 N N   . LYS A 230 ? 0.12390 0.20890 0.11230 -0.02270 -0.00930 0.01560  234 LYS A N   
3475 C CA  . LYS A 230 ? 0.10870 0.21580 0.11240 -0.00250 -0.00230 0.01350  234 LYS A CA  
3476 C C   . LYS A 230 ? 0.09430 0.23550 0.11020 -0.00740 -0.00240 0.00380  234 LYS A C   
3477 O O   . LYS A 230 ? 0.09060 0.24270 0.10980 -0.00330 0.00150  0.01190  234 LYS A O   
3478 C CB  . LYS A 230 ? 0.11150 0.21150 0.10340 -0.00800 0.00430  0.00740  234 LYS A CB  
3479 C CG  . LYS A 230 ? 0.12640 0.22090 0.09600 -0.01760 -0.00760 -0.00890 234 LYS A CG  
3480 C CD  . LYS A 230 ? 0.12280 0.24250 0.11060 -0.00680 -0.01290 0.00570  234 LYS A CD  
3481 C CE  . LYS A 230 ? 0.13690 0.23020 0.10820 -0.00950 -0.01920 -0.01330 234 LYS A CE  
3482 N NZ  . LYS A 230 ? 0.14860 0.22550 0.11720 -0.01740 -0.00260 0.00360  234 LYS A NZ  
3496 N N   . THR A 231 ? 0.11070 0.23620 0.10880 -0.01150 0.00500  -0.00050 235 THR A N   
3497 C CA  . THR A 231 ? 0.10640 0.22940 0.12170 -0.01860 -0.01150 -0.00050 235 THR A CA  
3498 C C   . THR A 231 ? 0.12130 0.22320 0.11980 -0.01410 -0.02230 -0.00290 235 THR A C   
3499 O O   . THR A 231 ? 0.12610 0.20050 0.11420 -0.01930 -0.01320 0.00350  235 THR A O   
3500 C CB  . THR A 231 ? 0.12990 0.23010 0.13010 -0.01140 -0.00610 0.00320  235 THR A CB  
3501 O OG1 . THR A 231 ? 0.13640 0.24600 0.15320 0.00200  -0.01680 0.00740  235 THR A OG1 
3502 C CG2 . THR A 231 ? 0.11310 0.20890 0.16550 -0.02620 0.02540  0.01690  235 THR A CG2 
3510 N N   . GLY A 232 ? 0.11070 0.21680 0.10350 -0.01280 -0.00140 0.01120  236 GLY A N   
3511 C CA  . GLY A 232 ? 0.13340 0.22770 0.11940 -0.01840 -0.00080 0.00500  236 GLY A CA  
3512 C C   . GLY A 232 ? 0.13090 0.23420 0.11810 0.00420  -0.00920 0.00130  236 GLY A C   
3513 O O   . GLY A 232 ? 0.13120 0.23970 0.10540 -0.00180 0.00240  -0.00960 236 GLY A O   
3517 N N   . THR A 233 ? 0.11580 0.24100 0.10740 0.00660  0.00090  0.01060  237 THR A N   
3518 C CA  . THR A 233 ? 0.14770 0.26980 0.13460 0.02520  0.00110  0.02400  237 THR A CA  
3519 C C   . THR A 233 ? 0.14930 0.24830 0.12180 0.02310  0.00480  0.00820  237 THR A C   
3520 O O   . THR A 233 ? 0.15200 0.25910 0.11090 -0.02290 -0.00400 0.01800  237 THR A O   
3521 C CB  . THR A 233 ? 0.16380 0.31190 0.16470 0.03920  0.02460  0.06300  237 THR A CB  
3522 O OG1 . THR A 233 ? 0.14140 0.34440 0.17810 0.04900  0.03010  0.10870  237 THR A OG1 
3523 C CG2 . THR A 233 ? 0.20390 0.31190 0.19280 0.04730  0.02400  0.04680  237 THR A CG2 
3531 N N   . CYS A 234 ? 0.14160 0.24890 0.11760 0.00140  0.00980  0.01620  238 CYS A N   
3532 C CA  . CYS A 234 ? 0.13810 0.24610 0.13400 -0.00180 -0.00230 0.01740  238 CYS A CA  
3533 C C   . CYS A 234 ? 0.15230 0.26680 0.17990 -0.01300 -0.01670 0.03110  238 CYS A C   
3534 O O   . CYS A 234 ? 0.17430 0.29140 0.19760 -0.02740 0.00030  0.06110  238 CYS A O   
3535 C CB  . CYS A 234 ? 0.14270 0.24760 0.13020 0.00190  -0.01190 0.01260  238 CYS A CB  
3536 S SG  . CYS A 234 ? 0.13230 0.21690 0.13520 -0.00720 0.00080  0.00670  238 CYS A SG  
3541 N N   . GLY A 235 ? 0.17670 0.24770 0.20990 -0.01200 -0.04650 0.02670  239 GLY A N   
3542 C CA  . GLY A 235 ? 0.21050 0.24120 0.22740 -0.03030 -0.02390 0.02230  239 GLY A CA  
3543 C C   . GLY A 235 ? 0.20140 0.22240 0.21630 -0.01650 -0.00390 0.01760  239 GLY A C   
3544 O O   . GLY A 235 ? 0.21490 0.22070 0.22420 -0.01090 -0.00720 0.01920  239 GLY A O   
3548 N N   . VAL A 236 ? 0.16850 0.19680 0.17140 -0.02950 -0.03070 0.01860  240 VAL A N   
3549 C CA  . VAL A 236 ? 0.16380 0.20240 0.15540 -0.00500 -0.01430 0.02290  240 VAL A CA  
3550 C C   . VAL A 236 ? 0.14570 0.19600 0.15260 0.00000  -0.00480 0.01280  240 VAL A C   
3551 O O   . VAL A 236 ? 0.16240 0.21500 0.13100 -0.00560 -0.01440 -0.00520 240 VAL A O   
3552 C CB  . VAL A 236 ? 0.18570 0.22950 0.15770 -0.00250 -0.01050 0.02680  240 VAL A CB  
3553 C CG1 . VAL A 236 ? 0.21660 0.24910 0.14970 0.00650  -0.01920 0.01540  240 VAL A CG1 
3554 C CG2 . VAL A 236 ? 0.17990 0.25510 0.15530 -0.02160 0.00030  0.02020  240 VAL A CG2 
3564 N N   . TYR A 237 ? 0.13060 0.17650 0.16190 0.00230  0.00210  0.01140  241 TYR A N   
3565 C CA  . TYR A 237 ? 0.13400 0.18180 0.13700 0.01410  0.00140  0.02670  241 TYR A CA  
3566 C C   . TYR A 237 ? 0.13790 0.17850 0.13290 -0.01150 -0.00210 0.01850  241 TYR A C   
3567 O O   . TYR A 237 ? 0.13710 0.17240 0.12600 -0.01140 -0.00810 0.00650  241 TYR A O   
3568 C CB  . TYR A 237 ? 0.11520 0.19950 0.13720 0.00900  -0.00460 0.00830  241 TYR A CB  
3569 C CG  . TYR A 237 ? 0.12440 0.19980 0.13200 -0.00230 -0.00250 -0.00520 241 TYR A CG  
3570 C CD1 . TYR A 237 ? 0.12430 0.19810 0.13080 -0.01120 0.00960  0.00150  241 TYR A CD1 
3571 C CD2 . TYR A 237 ? 0.13180 0.20250 0.14840 -0.02520 -0.00700 0.00520  241 TYR A CD2 
3572 C CE1 . TYR A 237 ? 0.13270 0.20820 0.16280 -0.01420 0.00610  -0.00080 241 TYR A CE1 
3573 C CE2 . TYR A 237 ? 0.15160 0.22300 0.14620 -0.03020 -0.00050 0.00660  241 TYR A CE2 
3574 C CZ  . TYR A 237 ? 0.13550 0.21790 0.17770 -0.02300 0.00810  0.01100  241 TYR A CZ  
3575 O OH  . TYR A 237 ? 0.15360 0.22860 0.19580 -0.00430 0.02910  0.03450  241 TYR A OH  
3585 N N   . GLY A 238 ? 0.15440 0.18840 0.15700 -0.01200 -0.00040 -0.00180 242 GLY A N   
3586 C CA  . GLY A 238 ? 0.14110 0.18990 0.16060 -0.01690 0.01140  0.00480  242 GLY A CA  
3587 C C   . GLY A 238 ? 0.14130 0.17080 0.13210 -0.02640 0.00500  -0.00650 242 GLY A C   
3588 O O   . GLY A 238 ? 0.15470 0.17830 0.14080 -0.01490 0.01390  -0.01290 242 GLY A O   
3592 N N   . THR A 239 ? 0.12770 0.17780 0.12150 -0.00480 -0.00450 0.00980  243 THR A N   
3593 C CA  . THR A 239 ? 0.15290 0.18650 0.11070 -0.00140 0.00740  0.00910  243 THR A CA  
3594 C C   . THR A 239 ? 0.14530 0.20570 0.12090 -0.00470 -0.01470 0.01470  243 THR A C   
3595 O O   . THR A 239 ? 0.14520 0.22170 0.12380 -0.01880 -0.00680 0.01430  243 THR A O   
3596 C CB  . THR A 239 ? 0.13680 0.17170 0.10320 0.02420  -0.01740 0.01390  243 THR A CB  
3597 O OG1 . THR A 239 ? 0.14780 0.19670 0.11630 0.02280  -0.00570 0.00060  243 THR A OG1 
3598 C CG2 . THR A 239 ? 0.14980 0.16230 0.12530 0.03360  -0.00320 0.02070  243 THR A CG2 
3606 N N   . ALA A 240 ? 0.14390 0.20970 0.10920 -0.02600 -0.01780 0.00970  244 ALA A N   
3607 C CA  . ALA A 240 ? 0.13990 0.20550 0.11220 -0.00130 -0.01700 0.01190  244 ALA A CA  
3608 C C   . ALA A 240 ? 0.13610 0.18850 0.10690 0.01270  -0.00120 -0.00330 244 ALA A C   
3609 O O   . ALA A 240 ? 0.14000 0.18660 0.11270 0.00870  -0.00670 0.00470  244 ALA A O   
3610 C CB  . ALA A 240 ? 0.14070 0.20440 0.13290 0.01080  -0.00120 0.03190  244 ALA A CB  
3616 N N   . ASN A 241 ? 0.12220 0.17590 0.12350 0.01040  -0.01470 0.00280  245 ASN A N   
3617 C CA  . ASN A 241 ? 0.12450 0.18540 0.10980 0.00890  -0.00120 -0.00200 245 ASN A CA  
3618 C C   . ASN A 241 ? 0.11330 0.19900 0.12200 0.00960  0.01060  0.00010  245 ASN A C   
3619 O O   . ASN A 241 ? 0.10610 0.20400 0.11770 -0.00090 -0.00270 0.00610  245 ASN A O   
3620 C CB  . ASN A 241 ? 0.12830 0.18420 0.10640 -0.01440 -0.00450 -0.00930 245 ASN A CB  
3621 C CG  . ASN A 241 ? 0.10670 0.20970 0.12420 -0.01710 0.01690  0.00240  245 ASN A CG  
3622 O OD1 . ASN A 241 ? 0.12830 0.23350 0.12010 -0.00970 -0.00610 -0.00460 245 ASN A OD1 
3623 N ND2 . ASN A 241 ? 0.13730 0.22370 0.10710 -0.00420 0.00970  -0.00170 245 ASN A ND2 
3630 N N   . ASP A 242 ? 0.11340 0.20410 0.09990 -0.00290 0.00230  0.01080  246 ASP A N   
3631 C CA  . ASP A 242 ? 0.12840 0.21960 0.09910 -0.01990 0.00890  0.00700  246 ASP A CA  
3632 C C   . ASP A 242 ? 0.11380 0.23840 0.10510 -0.00580 0.01780  0.00060  246 ASP A C   
3633 O O   . ASP A 242 ? 0.14190 0.24150 0.10250 -0.01390 -0.00850 -0.00390 246 ASP A O   
3634 C CB  . ASP A 242 ? 0.12110 0.23250 0.09860 -0.01080 -0.00650 -0.00100 246 ASP A CB  
3635 C CG  . ASP A 242 ? 0.11620 0.23000 0.12290 -0.02200 -0.00350 0.00230  246 ASP A CG  
3636 O OD1 . ASP A 242 ? 0.10760 0.23130 0.12740 -0.01410 0.00010  -0.02300 246 ASP A OD1 
3637 O OD2 . ASP A 242 ? 0.12160 0.22620 0.10930 -0.00950 0.01130  0.00350  246 ASP A OD2 
3642 N N   . TYR A 243 ? 0.12640 0.24180 0.09030 -0.01290 0.01270  0.00420  247 TYR A N   
3643 C CA  . TYR A 243 ? 0.13100 0.22570 0.10470 -0.01830 -0.00540 0.00530  247 TYR A CA  
3644 C C   . TYR A 243 ? 0.11450 0.21200 0.11960 -0.01720 0.00910  -0.00030 247 TYR A C   
3645 O O   . TYR A 243 ? 0.11120 0.22700 0.11550 -0.00120 0.00770  0.00950  247 TYR A O   
3646 C CB  . TYR A 243 ? 0.13300 0.20540 0.10720 -0.00720 0.00830  -0.00620 247 TYR A CB  
3647 C CG  . TYR A 243 ? 0.12620 0.20200 0.12530 -0.01340 -0.01290 0.00640  247 TYR A CG  
3648 C CD1 . TYR A 243 ? 0.10720 0.21120 0.13800 -0.03060 -0.00750 0.02080  247 TYR A CD1 
3649 C CD2 . TYR A 243 ? 0.13350 0.18630 0.12480 -0.00730 -0.02100 -0.00000 247 TYR A CD2 
3650 C CE1 . TYR A 243 ? 0.10700 0.20910 0.13120 -0.01910 -0.01440 0.00430  247 TYR A CE1 
3651 C CE2 . TYR A 243 ? 0.11970 0.19750 0.12560 -0.00030 -0.01670 -0.00420 247 TYR A CE2 
3652 C CZ  . TYR A 243 ? 0.12340 0.21300 0.12190 -0.00860 -0.01560 -0.01930 247 TYR A CZ  
3653 O OH  . TYR A 243 ? 0.13780 0.21290 0.11880 -0.00360 0.00270  -0.01060 247 TYR A OH  
3663 N N   . ALA A 244 ? 0.10430 0.21300 0.11990 -0.00770 -0.00190 0.01880  248 ALA A N   
3664 C CA  . ALA A 244 ? 0.12020 0.21440 0.14000 -0.01170 0.00370  0.00910  248 ALA A CA  
3665 C C   . ALA A 244 ? 0.11550 0.22020 0.13150 -0.00130 0.00580  0.01320  248 ALA A C   
3666 O O   . ALA A 244 ? 0.13440 0.24570 0.11820 -0.00530 0.00970  0.02350  248 ALA A O   
3667 C CB  . ALA A 244 ? 0.12440 0.21420 0.13130 -0.01740 -0.00380 0.02030  248 ALA A CB  
3673 N N   A VAL A 245 ? 0.13490 0.20720 0.12100 -0.00630 -0.00250 0.01340  249 VAL A N   
3674 N N   B VAL A 245 ? 0.11780 0.20490 0.14140 -0.01360 -0.00370 0.00970  249 VAL A N   
3675 C CA  A VAL A 245 ? 0.13360 0.20170 0.14220 -0.01630 0.00280  0.02900  249 VAL A CA  
3676 C CA  B VAL A 245 ? 0.11490 0.20080 0.15320 -0.02230 -0.01300 0.01420  249 VAL A CA  
3677 C C   A VAL A 245 ? 0.12740 0.20960 0.13760 -0.00710 0.00550  0.03160  249 VAL A C   
3678 C C   B VAL A 245 ? 0.12030 0.21010 0.15880 -0.02390 -0.01300 0.01840  249 VAL A C   
3679 O O   A VAL A 245 ? 0.12470 0.20630 0.11930 -0.00740 0.01690  0.01640  249 VAL A O   
3680 O O   B VAL A 245 ? 0.12040 0.20020 0.16800 -0.03900 -0.02600 0.00420  249 VAL A O   
3681 C CB  A VAL A 245 ? 0.16620 0.19280 0.17280 -0.00380 0.01670  0.01630  249 VAL A CB  
3682 C CB  B VAL A 245 ? 0.11720 0.19130 0.16010 -0.01780 -0.02460 0.00920  249 VAL A CB  
3683 C CG1 A VAL A 245 ? 0.20670 0.19130 0.17400 0.00680  0.00360  0.02190  249 VAL A CG1 
3684 C CG1 B VAL A 245 ? 0.11840 0.19090 0.16600 -0.02290 -0.01280 0.00910  249 VAL A CG1 
3685 C CG2 A VAL A 245 ? 0.17210 0.19580 0.16520 0.01430  0.04860  -0.00020 249 VAL A CG2 
3686 C CG2 B VAL A 245 ? 0.12800 0.18920 0.15640 -0.00730 -0.04450 0.00870  249 VAL A CG2 
3705 N N   . VAL A 246 ? 0.13600 0.23490 0.14810 -0.01120 0.00150  0.03050  250 VAL A N   
3706 C CA  . VAL A 246 ? 0.13060 0.26010 0.15090 -0.01280 0.00880  0.01560  250 VAL A CA  
3707 C C   . VAL A 246 ? 0.14350 0.27070 0.15290 -0.00930 0.02120  0.02760  250 VAL A C   
3708 O O   . VAL A 246 ? 0.14000 0.28180 0.14330 0.01370  0.01620  0.05290  250 VAL A O   
3709 C CB  . VAL A 246 ? 0.12840 0.26220 0.15710 -0.01970 0.01800  0.01490  250 VAL A CB  
3710 C CG1 . VAL A 246 ? 0.13290 0.27660 0.17820 -0.00680 0.03240  0.01720  250 VAL A CG1 
3711 C CG2 . VAL A 246 ? 0.14350 0.25750 0.17980 -0.01570 0.01360  0.01560  250 VAL A CG2 
3722 N N   . TRP A 247 ? 0.15720 0.26920 0.17170 -0.01860 -0.00340 0.03050  251 TRP A N   
3723 C CA  . TRP A 247 ? 0.13930 0.27780 0.18400 -0.01660 0.01510  0.03300  251 TRP A CA  
3724 C C   . TRP A 247 ? 0.14010 0.30070 0.19430 -0.01490 0.02440  0.02810  251 TRP A C   
3725 O O   . TRP A 247 ? 0.13230 0.32030 0.19270 -0.02020 0.00810  0.02010  251 TRP A O   
3726 C CB  . TRP A 247 ? 0.15480 0.27240 0.21290 -0.02110 0.02330  -0.00830 251 TRP A CB  
3727 C CG  . TRP A 247 ? 0.16630 0.27610 0.20640 -0.02650 -0.00160 -0.02190 251 TRP A CG  
3728 C CD1 . TRP A 247 ? 0.19550 0.27890 0.20100 -0.03860 -0.01510 -0.01770 251 TRP A CD1 
3729 C CD2 . TRP A 247 ? 0.15670 0.28210 0.19910 -0.03950 -0.00330 -0.03640 251 TRP A CD2 
3730 N NE1 . TRP A 247 ? 0.19860 0.28450 0.20690 -0.03920 -0.00790 -0.02780 251 TRP A NE1 
3731 C CE2 . TRP A 247 ? 0.18020 0.28720 0.19870 -0.04980 -0.00240 -0.04060 251 TRP A CE2 
3732 C CE3 . TRP A 247 ? 0.16110 0.29250 0.20980 -0.03440 0.02260  -0.03870 251 TRP A CE3 
3733 C CZ2 . TRP A 247 ? 0.17520 0.29190 0.22210 -0.05380 -0.00070 -0.05360 251 TRP A CZ2 
3734 C CZ3 . TRP A 247 ? 0.17220 0.29390 0.20830 -0.03120 0.02470  -0.05730 251 TRP A CZ3 
3735 C CH2 . TRP A 247 ? 0.20270 0.29340 0.20180 -0.02990 0.00220  -0.05050 251 TRP A CH2 
3746 N N   . PRO A 248 ? 0.11860 0.29240 0.18250 -0.00330 0.04060  0.03220  252 PRO A N   
3747 C CA  . PRO A 248 ? 0.11820 0.28620 0.18960 -0.00460 0.03320  0.04570  252 PRO A CA  
3748 C C   . PRO A 248 ? 0.13960 0.27990 0.22370 0.01380  0.05020  0.03680  252 PRO A C   
3749 O O   . PRO A 248 ? 0.17160 0.29190 0.30140 0.01840  0.09350  0.02420  252 PRO A O   
3750 C CB  . PRO A 248 ? 0.13860 0.28690 0.19490 0.00920  0.03130  0.04090  252 PRO A CB  
3751 C CG  . PRO A 248 ? 0.12410 0.28730 0.20260 0.01660  0.03680  0.03770  252 PRO A CG  
3752 C CD  . PRO A 248 ? 0.12370 0.28950 0.18990 0.00190  0.02430  0.03030  252 PRO A CD  
3760 N N   . THR A 249 ? 0.11200 0.26920 0.16850 0.00410  0.05690  0.03030  254 THR A N   
3761 C CA  . THR A 249 ? 0.15310 0.26940 0.16990 -0.00020 0.04950  0.01150  254 THR A CA  
3762 C C   . THR A 249 ? 0.14720 0.28980 0.18170 0.00310  0.05990  0.02600  254 THR A C   
3763 O O   . THR A 249 ? 0.16980 0.29920 0.17710 0.00210  0.03350  0.02830  254 THR A O   
3764 C CB  . THR A 249 ? 0.14510 0.26280 0.14680 -0.00960 0.02580  -0.00770 254 THR A CB  
3765 O OG1 . THR A 249 ? 0.12100 0.25880 0.15250 -0.01760 0.02050  -0.01190 254 THR A OG1 
3766 C CG2 . THR A 249 ? 0.18280 0.28330 0.16030 0.01380  0.01940  -0.01000 254 THR A CG2 
3774 N N   . GLY A 250 ? 0.15630 0.29890 0.21100 0.02330  0.05580  0.02280  255 GLY A N   
3775 C CA  . GLY A 250 ? 0.17780 0.31570 0.21790 0.02230  0.03610  0.04870  255 GLY A CA  
3776 C C   . GLY A 250 ? 0.18170 0.32760 0.23720 -0.00440 0.04320  0.07010  255 GLY A C   
3777 O O   . GLY A 250 ? 0.17420 0.34580 0.26400 -0.01380 0.03980  0.09240  255 GLY A O   
3781 N N   . ARG A 251 ? 0.15630 0.32170 0.21630 0.00370  0.04770  0.06820  256 ARG A N   
3782 C CA  . ARG A 251 ? 0.16010 0.31090 0.21590 0.00130  0.05350  0.06890  256 ARG A CA  
3783 C C   . ARG A 251 ? 0.14030 0.30270 0.22580 0.01160  0.04400  0.07360  256 ARG A C   
3784 O O   . ARG A 251 ? 0.16090 0.31450 0.21630 0.00740  0.04140  0.05400  256 ARG A O   
3785 C CB  . ARG A 251 ? 0.18250 0.32430 0.23170 -0.00030 0.04200  0.06500  256 ARG A CB  
3786 C CG  . ARG A 251 ? 0.18900 0.33240 0.21760 0.01560  0.04060  0.06340  256 ARG A CG  
3787 C CD  . ARG A 251 ? 0.21560 0.35830 0.21530 0.02460  0.03580  0.04040  256 ARG A CD  
3788 N NE  . ARG A 251 ? 0.23380 0.37890 0.21750 0.02840  0.02570  0.01670  256 ARG A NE  
3789 C CZ  . ARG A 251 ? 0.23240 0.38630 0.23340 0.03480  0.03540  0.00660  256 ARG A CZ  
3790 N NH1 . ARG A 251 ? 0.26090 0.39110 0.24740 0.03430  0.04720  0.02600  256 ARG A NH1 
3791 N NH2 . ARG A 251 ? 0.22960 0.38560 0.25740 0.02520  0.03070  0.02320  256 ARG A NH2 
3805 N N   . ALA A 252 ? 0.15130 0.28970 0.24210 0.01660  0.03810  0.07840  257 ALA A N   
3806 C CA  . ALA A 252 ? 0.14940 0.26910 0.24070 0.01830  0.03670  0.06220  257 ALA A CA  
3807 C C   . ALA A 252 ? 0.14470 0.26510 0.20250 0.02370  0.04710  0.04330  257 ALA A C   
3808 O O   . ALA A 252 ? 0.13440 0.25500 0.19410 0.02670  0.02600  0.04480  257 ALA A O   
3809 C CB  . ALA A 252 ? 0.15870 0.26880 0.26390 0.02100  0.04020  0.07920  257 ALA A CB  
3815 N N   . PRO A 253 ? 0.15670 0.25580 0.18950 -0.00630 0.03310  0.01860  258 PRO A N   
3816 C CA  . PRO A 253 ? 0.16710 0.24830 0.17420 -0.00670 0.03400  0.02300  258 PRO A CA  
3817 C C   . PRO A 253 ? 0.16010 0.22950 0.16270 -0.00520 0.02330  0.04630  258 PRO A C   
3818 O O   . PRO A 253 ? 0.14960 0.23220 0.19750 -0.00860 0.02180  0.03740  258 PRO A O   
3819 C CB  . PRO A 253 ? 0.21640 0.26700 0.17930 -0.01580 0.02540  -0.01250 258 PRO A CB  
3820 C CG  . PRO A 253 ? 0.21350 0.27670 0.20810 0.00190  0.03070  -0.01500 258 PRO A CG  
3821 C CD  . PRO A 253 ? 0.17800 0.26060 0.21980 -0.00310 0.03650  0.00510  258 PRO A CD  
3829 N N   . ILE A 254 ? 0.14730 0.21640 0.14050 0.00850  0.03260  0.05050  259 ILE A N   
3830 C CA  . ILE A 254 ? 0.14680 0.23450 0.14480 -0.02240 0.00690  0.05720  259 ILE A CA  
3831 C C   . ILE A 254 ? 0.13910 0.24150 0.14960 -0.01980 0.00950  0.05430  259 ILE A C   
3832 O O   . ILE A 254 ? 0.11150 0.27520 0.14530 -0.00360 0.01380  0.04640  259 ILE A O   
3833 C CB  . ILE A 254 ? 0.16390 0.25160 0.15340 -0.02330 0.02810  0.04080  259 ILE A CB  
3834 C CG1 . ILE A 254 ? 0.18810 0.26000 0.18030 -0.02690 0.03150  0.03910  259 ILE A CG1 
3835 C CG2 . ILE A 254 ? 0.16020 0.24660 0.15720 -0.01550 0.02720  0.04140  259 ILE A CG2 
3836 C CD1 . ILE A 254 ? 0.19060 0.28270 0.19580 -0.01620 0.01400  0.05790  259 ILE A CD1 
3848 N N   . VAL A 255 ? 0.13420 0.22590 0.14190 -0.02050 0.00510  0.05250  260 VAL A N   
3849 C CA  . VAL A 255 ? 0.14510 0.23150 0.14450 -0.03710 0.00410  0.03350  260 VAL A CA  
3850 C C   . VAL A 255 ? 0.12990 0.22660 0.13820 -0.02580 0.00830  0.03650  260 VAL A C   
3851 O O   . VAL A 255 ? 0.11800 0.24510 0.14110 -0.02430 -0.00530 0.02680  260 VAL A O   
3852 C CB  . VAL A 255 ? 0.15200 0.22590 0.14730 -0.02950 0.01320  0.04900  260 VAL A CB  
3853 C CG1 . VAL A 255 ? 0.16600 0.22980 0.14740 -0.02820 0.01390  0.03070  260 VAL A CG1 
3854 C CG2 . VAL A 255 ? 0.16740 0.24780 0.16370 -0.02280 0.03280  0.02430  260 VAL A CG2 
3864 N N   . LEU A 256 ? 0.14460 0.24440 0.11590 -0.01520 0.00670  0.02590  261 LEU A N   
3865 C CA  . LEU A 256 ? 0.15040 0.23680 0.12310 -0.01960 0.00250  0.03070  261 LEU A CA  
3866 C C   . LEU A 256 ? 0.13720 0.22580 0.12490 -0.02560 -0.00480 0.01290  261 LEU A C   
3867 O O   . LEU A 256 ? 0.13880 0.23800 0.11390 -0.01080 -0.00260 0.03730  261 LEU A O   
3868 C CB  . LEU A 256 ? 0.16270 0.22530 0.12920 -0.00430 -0.00470 0.00680  261 LEU A CB  
3869 C CG  . LEU A 256 ? 0.17860 0.23280 0.13610 0.01310  -0.01450 0.01870  261 LEU A CG  
3870 C CD1 . LEU A 256 ? 0.18080 0.25470 0.16830 0.01830  -0.02300 0.00040  261 LEU A CD1 
3871 C CD2 . LEU A 256 ? 0.16840 0.23320 0.15730 0.01590  -0.01270 0.01770  261 LEU A CD2 
3883 N N   . ALA A 257 ? 0.14270 0.20360 0.10150 -0.02040 -0.00400 0.01980  262 ALA A N   
3884 C CA  . ALA A 257 ? 0.12840 0.22250 0.11470 -0.02500 -0.02460 0.02740  262 ALA A CA  
3885 C C   . ALA A 257 ? 0.11660 0.22710 0.10650 -0.01810 -0.01570 0.02290  262 ALA A C   
3886 O O   . ALA A 257 ? 0.13040 0.23700 0.11010 -0.01230 -0.00800 0.00500  262 ALA A O   
3887 C CB  . ALA A 257 ? 0.13740 0.23250 0.12170 -0.01650 0.00320  0.01810  262 ALA A CB  
3893 N N   . VAL A 258 ? 0.09240 0.22170 0.10050 -0.01710 -0.00680 0.01270  263 VAL A N   
3894 C CA  . VAL A 258 ? 0.10760 0.22630 0.11290 -0.02810 -0.00870 0.01890  263 VAL A CA  
3895 C C   . VAL A 258 ? 0.10600 0.21970 0.11110 -0.01780 0.00710  0.01450  263 VAL A C   
3896 O O   . VAL A 258 ? 0.12330 0.22950 0.10300 -0.00270 -0.00590 0.01470  263 VAL A O   
3897 C CB  . VAL A 258 ? 0.12140 0.24150 0.13050 -0.01010 0.00100  0.02920  263 VAL A CB  
3898 C CG1 . VAL A 258 ? 0.14540 0.25250 0.13530 -0.00380 0.00710  0.02650  263 VAL A CG1 
3899 C CG2 . VAL A 258 ? 0.13410 0.24890 0.13970 -0.00080 0.00600  0.01890  263 VAL A CG2 
3909 N N   . TYR A 259 ? 0.13240 0.19830 0.10400 -0.03470 0.00310  0.00590  264 TYR A N   
3910 C CA  . TYR A 259 ? 0.10780 0.18940 0.11250 -0.02210 -0.00980 0.00840  264 TYR A CA  
3911 C C   . TYR A 259 ? 0.11760 0.20490 0.12400 -0.01050 -0.00320 0.00450  264 TYR A C   
3912 O O   . TYR A 259 ? 0.15180 0.21580 0.09330 -0.01030 -0.00740 0.00020  264 TYR A O   
3913 C CB  . TYR A 259 ? 0.10720 0.11600 0.18770 -0.03950 0.02080  0.00660  264 TYR A CB  
3914 C CG  . TYR A 259 ? 0.15240 0.07990 0.16900 -0.04270 0.00860  -0.04140 264 TYR A CG  
3915 C CD1 . TYR A 259 ? 0.15560 0.06340 0.17650 -0.03520 -0.01270 -0.02450 264 TYR A CD1 
3916 C CD2 . TYR A 259 ? 0.17060 0.08780 0.17390 -0.05020 0.00780  -0.04240 264 TYR A CD2 
3917 C CE1 . TYR A 259 ? 0.17490 0.09340 0.19730 -0.05960 0.01130  -0.03410 264 TYR A CE1 
3918 C CE2 . TYR A 259 ? 0.14330 0.07030 0.16980 -0.03540 -0.02200 -0.02930 264 TYR A CE2 
3919 C CZ  . TYR A 259 ? 0.18400 0.09770 0.18680 -0.05260 -0.00910 -0.04940 264 TYR A CZ  
3920 O OH  . TYR A 259 ? 0.12280 0.11620 0.15030 -0.01850 0.02390  0.00460  264 TYR A OH  
3930 N N   . THR A 260 ? 0.11570 0.19770 0.10330 -0.00160 0.00130  -0.00580 265 THR A N   
3931 C CA  . THR A 260 ? 0.11810 0.20420 0.10840 0.00230  -0.01700 -0.00450 265 THR A CA  
3932 C C   . THR A 260 ? 0.13990 0.22740 0.12100 -0.01090 -0.00620 -0.00610 265 THR A C   
3933 O O   . THR A 260 ? 0.13440 0.23080 0.11490 -0.00240 -0.00540 -0.00350 265 THR A O   
3934 C CB  . THR A 260 ? 0.13240 0.21540 0.11830 0.01990  0.00390  -0.01010 265 THR A CB  
3935 O OG1 . THR A 260 ? 0.13170 0.19870 0.12570 0.02230  -0.00430 -0.00590 265 THR A OG1 
3936 C CG2 . THR A 260 ? 0.12000 0.21490 0.14170 0.00590  0.01230  -0.00210 265 THR A CG2 
3944 N N   . ARG A 261 ? 0.13160 0.23690 0.10790 -0.01590 0.00560  -0.00510 266 ARG A N   
3945 C CA  . ARG A 261 ? 0.13670 0.22260 0.13000 -0.01130 0.00650  0.01030  266 ARG A CA  
3946 C C   . ARG A 261 ? 0.13200 0.21420 0.13700 -0.02050 -0.00240 -0.00130 266 ARG A C   
3947 O O   . ARG A 261 ? 0.15940 0.21740 0.13040 -0.03480 0.02330  -0.01140 266 ARG A O   
3948 C CB  . ARG A 261 ? 0.13510 0.23150 0.11120 -0.00550 0.01830  0.00480  266 ARG A CB  
3949 C CG  . ARG A 261 ? 0.13770 0.25080 0.15530 0.03210  0.02850  0.01050  266 ARG A CG  
3950 C CD  . ARG A 261 ? 0.15740 0.29150 0.17940 0.05220  -0.02150 0.00380  266 ARG A CD  
3951 N NE  . ARG A 261 ? 0.23840 0.34050 0.23490 0.03660  -0.00310 -0.01110 266 ARG A NE  
3952 C CZ  . ARG A 261 ? 0.23700 0.33680 0.24690 0.03510  -0.04740 -0.04080 266 ARG A CZ  
3953 N NH1 . ARG A 261 ? 0.26380 0.34590 0.31740 0.03270  -0.01840 -0.03000 266 ARG A NH1 
3954 N NH2 . ARG A 261 ? 0.21370 0.29740 0.15680 0.03060  -0.03830 -0.02150 266 ARG A NH2 
3968 N N   . ALA A 262 ? 0.15170 0.20070 0.13160 -0.01810 0.00350  -0.01180 267 ALA A N   
3969 C CA  . ALA A 262 ? 0.14650 0.19290 0.15240 -0.00970 -0.00440 -0.00250 267 ALA A CA  
3970 C C   . ALA A 262 ? 0.14580 0.19500 0.13060 -0.02290 -0.00070 -0.01620 267 ALA A C   
3971 O O   . ALA A 262 ? 0.15130 0.19640 0.13370 -0.02240 -0.01390 -0.00620 267 ALA A O   
3972 C CB  . ALA A 262 ? 0.14870 0.19520 0.17770 0.00490  -0.00120 -0.00080 267 ALA A CB  
3978 N N   . PRO A 263 ? 0.14720 0.22210 0.13440 -0.02910 0.00830  -0.01720 268 PRO A N   
3979 C CA  . PRO A 263 ? 0.13660 0.23110 0.12760 -0.02280 -0.00570 -0.00050 268 PRO A CA  
3980 C C   . PRO A 263 ? 0.13670 0.22930 0.14340 -0.03940 -0.00280 0.00010  268 PRO A C   
3981 O O   . PRO A 263 ? 0.12940 0.23050 0.14750 -0.01840 0.00930  -0.00290 268 PRO A O   
3982 C CB  . PRO A 263 ? 0.16380 0.24480 0.15670 -0.03630 -0.01540 -0.02010 268 PRO A CB  
3983 C CG  . PRO A 263 ? 0.20420 0.26080 0.15230 -0.03130 0.00470  -0.05400 268 PRO A CG  
3984 C CD  . PRO A 263 ? 0.16900 0.24610 0.13150 -0.02170 -0.01270 -0.03860 268 PRO A CD  
3992 N N   . ASN A 264 ? 0.13220 0.23680 0.16210 -0.02760 -0.00180 0.02060  269 ASN A N   
3993 C CA  . ASN A 264 ? 0.14180 0.23200 0.17180 -0.02430 0.00400  0.00240  269 ASN A CA  
3994 C C   . ASN A 264 ? 0.13210 0.21820 0.17240 -0.01310 -0.00010 0.00950  269 ASN A C   
3995 O O   . ASN A 264 ? 0.11980 0.23580 0.17340 0.00030  0.00220  0.00750  269 ASN A O   
3996 C CB  . ASN A 264 ? 0.17410 0.24520 0.18040 -0.03060 -0.01410 0.00930  269 ASN A CB  
3997 C CG  . ASN A 264 ? 0.23590 0.29300 0.19040 -0.03280 0.00080  0.01470  269 ASN A CG  
3998 O OD1 . ASN A 264 ? 0.23670 0.31340 0.16870 -0.05650 -0.01200 0.02890  269 ASN A OD1 
3999 N ND2 . ASN A 264 ? 0.30140 0.31890 0.26590 0.00450  0.01270  -0.05010 269 ASN A ND2 
4006 N N   . LYS A 265 ? 0.12120 0.19290 0.17330 -0.01600 0.01450  0.02910  270 LYS A N   
4007 C CA  . LYS A 265 ? 0.10040 0.20700 0.18250 -0.03560 -0.00650 0.03550  270 LYS A CA  
4008 C C   . LYS A 265 ? 0.13540 0.23370 0.21480 -0.00550 -0.00790 0.03750  270 LYS A C   
4009 O O   . LYS A 265 ? 0.13420 0.25310 0.20350 -0.01290 -0.03690 0.03410  270 LYS A O   
4010 C CB  . LYS A 265 ? 0.12150 0.21750 0.17790 -0.04180 -0.00540 0.03030  270 LYS A CB  
4011 C CG  . LYS A 265 ? 0.17020 0.21600 0.17090 -0.04810 -0.02890 0.00840  270 LYS A CG  
4012 C CD  . LYS A 265 ? 0.21380 0.23610 0.16250 -0.03270 -0.00800 0.00300  270 LYS A CD  
4013 C CE  . LYS A 265 ? 0.25610 0.26430 0.19940 -0.02740 0.01460  0.00850  270 LYS A CE  
4014 N NZ  . LYS A 265 ? 0.29490 0.28710 0.21700 -0.03250 0.00360  0.01190  270 LYS A NZ  
4028 N N   . ASP A 266 ? 0.13340 0.23960 0.22450 0.02020  0.00720  0.04290  271 ASP A N   
4029 C CA  . ASP A 266 ? 0.15340 0.24850 0.28870 0.04240  0.01730  0.05390  271 ASP A CA  
4030 C C   . ASP A 266 ? 0.15940 0.23360 0.26400 0.03190  0.02030  0.03090  271 ASP A C   
4031 O O   . ASP A 266 ? 0.17200 0.22380 0.27350 0.01310  0.02370  0.02050  271 ASP A O   
4032 C CB  . ASP A 266 ? 0.23240 0.27700 0.39070 0.05260  0.03610  0.06570  271 ASP A CB  
4033 C CG  . ASP A 266 ? 0.29490 0.29540 0.46760 0.05030  0.04140  0.07890  271 ASP A CG  
4034 O OD1 . ASP A 266 ? 0.32200 0.30660 0.50160 0.03840  0.05590  0.06890  271 ASP A OD1 
4035 O OD2 . ASP A 266 ? 0.33660 0.31250 0.51370 0.04940  0.04380  0.09280  271 ASP A OD2 
4040 N N   . ASP A 267 ? 0.15360 0.22410 0.23000 0.01360  0.01280  0.02010  272 ASP A N   
4041 C CA  . ASP A 267 ? 0.13550 0.22800 0.22520 0.00590  0.00610  0.01340  272 ASP A CA  
4042 C C   . ASP A 267 ? 0.16510 0.23290 0.23870 0.00160  -0.00210 0.01470  272 ASP A C   
4043 O O   . ASP A 267 ? 0.15770 0.23070 0.22450 -0.00910 -0.00230 0.00350  272 ASP A O   
4044 C CB  . ASP A 267 ? 0.16660 0.23780 0.19550 0.01200  0.00600  -0.00090 272 ASP A CB  
4045 C CG  . ASP A 267 ? 0.18420 0.23280 0.20430 -0.00260 0.02160  -0.02420 272 ASP A CG  
4046 O OD1 . ASP A 267 ? 0.24100 0.23270 0.24340 -0.00660 -0.00130 -0.04950 272 ASP A OD1 
4047 O OD2 . ASP A 267 ? 0.16670 0.23560 0.18700 -0.02540 0.02370  -0.01020 272 ASP A OD2 
4052 N N   . LYS A 268 ? 0.16520 0.23960 0.27850 -0.01960 0.02420  0.01500  273 LYS A N   
4053 C CA  A LYS A 268 ? 0.16720 0.24120 0.26160 -0.01720 0.00920  0.01410  273 LYS A CA  
4054 C CA  B LYS A 268 ? 0.16050 0.23990 0.27170 -0.01320 0.00570  0.02630  273 LYS A CA  
4055 C C   . LYS A 268 ? 0.15780 0.23690 0.22280 -0.01280 0.01000  0.01080  273 LYS A C   
4056 O O   . LYS A 268 ? 0.20850 0.24400 0.20770 -0.01400 -0.00910 -0.00980 273 LYS A O   
4057 C CB  A LYS A 268 ? 0.19950 0.24980 0.28780 -0.01630 0.00630  0.01540  273 LYS A CB  
4058 C CB  B LYS A 268 ? 0.18970 0.24580 0.31790 -0.00790 -0.00430 0.05410  273 LYS A CB  
4059 C CG  A LYS A 268 ? 0.23540 0.26330 0.31530 -0.01180 0.00730  0.00030  273 LYS A CG  
4060 C CG  B LYS A 268 ? 0.23270 0.25320 0.34990 -0.00220 -0.01100 0.05720  273 LYS A CG  
4061 C CD  A LYS A 268 ? 0.25720 0.28010 0.34760 -0.01170 0.01360  -0.02040 273 LYS A CD  
4062 C CD  B LYS A 268 ? 0.26340 0.27510 0.38060 0.00200  -0.01060 0.06060  273 LYS A CD  
4063 C CE  A LYS A 268 ? 0.26270 0.29010 0.36860 -0.02480 0.01930  -0.03550 273 LYS A CE  
4064 C CE  B LYS A 268 ? 0.28680 0.28900 0.39320 0.00710  -0.01190 0.06960  273 LYS A CE  
4065 N NZ  A LYS A 268 ? 0.26030 0.29670 0.39450 -0.03020 0.02910  -0.04260 273 LYS A NZ  
4066 N NZ  B LYS A 268 ? 0.30960 0.29750 0.40150 0.01220  -0.02400 0.08600  273 LYS A NZ  
4093 N N   . HIS A 269 ? 0.14800 0.23620 0.16940 -0.00280 0.01140  0.02210  274 HIS A N   
4094 C CA  . HIS A 269 ? 0.13640 0.22770 0.15340 0.01340  -0.00460 0.01310  274 HIS A CA  
4095 C C   . HIS A 269 ? 0.15560 0.23010 0.16720 0.03040  0.00400  0.01560  274 HIS A C   
4096 O O   . HIS A 269 ? 0.16320 0.23820 0.17560 0.01180  0.00150  0.03010  274 HIS A O   
4097 C CB  . HIS A 269 ? 0.14790 0.24440 0.17580 0.01330  0.00300  0.01630  274 HIS A CB  
4098 C CG  . HIS A 269 ? 0.17770 0.26990 0.18790 0.02140  0.00020  0.02260  274 HIS A CG  
4099 N ND1 . HIS A 269 ? 0.23520 0.28470 0.20430 0.02280  -0.01470 0.00570  274 HIS A ND1 
4100 C CD2 . HIS A 269 ? 0.18080 0.29510 0.19180 0.01510  0.00920  0.00790  274 HIS A CD2 
4101 C CE1 . HIS A 269 ? 0.24320 0.30430 0.21560 0.00820  -0.03800 0.01690  274 HIS A CE1 
4102 N NE2 . HIS A 269 ? 0.19010 0.31000 0.21960 0.00800  -0.02750 -0.01590 274 HIS A NE2 
4110 N N   . SER A 270 ? 0.16850 0.24090 0.15850 0.01680  0.01580  0.00700  275 SER A N   
4111 C CA  . SER A 270 ? 0.16830 0.23630 0.14940 0.01430  0.01780  0.00470  275 SER A CA  
4112 C C   . SER A 270 ? 0.14880 0.24480 0.14830 0.01860  0.01560  0.00950  275 SER A C   
4113 O O   . SER A 270 ? 0.11670 0.26020 0.17370 -0.00560 0.00590  0.00840  275 SER A O   
4114 C CB  . SER A 270 ? 0.19370 0.23740 0.16710 0.00690  0.03110  -0.02090 275 SER A CB  
4115 O OG  . SER A 270 ? 0.21000 0.25020 0.17160 -0.00930 0.04080  -0.02910 275 SER A OG  
4121 N N   . GLU A 271 ? 0.15120 0.22560 0.15120 0.03210  -0.00570 0.01320  276 GLU A N   
4122 C CA  . GLU A 271 ? 0.14710 0.23350 0.16530 -0.00050 -0.00330 0.02820  276 GLU A CA  
4123 C C   . GLU A 271 ? 0.14400 0.24820 0.15640 -0.00290 0.00680  0.01000  276 GLU A C   
4124 O O   . GLU A 271 ? 0.12840 0.23370 0.15750 -0.01690 0.00540  -0.00560 276 GLU A O   
4125 C CB  . GLU A 271 ? 0.16790 0.23530 0.16020 -0.00850 0.00890  0.03010  276 GLU A CB  
4126 C CG  . GLU A 271 ? 0.17410 0.24120 0.17370 -0.00650 0.00560  0.01870  276 GLU A CG  
4127 C CD  . GLU A 271 ? 0.15120 0.24180 0.18430 -0.00390 -0.01680 0.02190  276 GLU A CD  
4128 O OE1 . GLU A 271 ? 0.16620 0.25190 0.24160 0.02050  -0.03640 0.01370  276 GLU A OE1 
4129 O OE2 . GLU A 271 ? 0.13990 0.23350 0.18840 -0.01110 -0.01370 0.00650  276 GLU A OE2 
4136 N N   . ALA A 272 ? 0.14880 0.26490 0.16030 0.02540  0.01040  0.01470  277 ALA A N   
4137 C CA  . ALA A 272 ? 0.17500 0.26630 0.15090 0.04960  0.02330  0.01620  277 ALA A CA  
4138 C C   . ALA A 272 ? 0.17060 0.26790 0.14300 0.02480  0.02880  0.00640  277 ALA A C   
4139 O O   . ALA A 272 ? 0.17290 0.28030 0.14300 0.02180  0.02060  0.01590  277 ALA A O   
4140 C CB  . ALA A 272 ? 0.21130 0.26860 0.17080 0.05180  0.02860  0.02570  277 ALA A CB  
4146 N N   . VAL A 273 ? 0.16550 0.25800 0.14200 0.01280  0.03390  0.00960  278 VAL A N   
4147 C CA  . VAL A 273 ? 0.15750 0.26470 0.14850 0.01160  0.02460  0.00460  278 VAL A CA  
4148 C C   . VAL A 273 ? 0.13730 0.26280 0.13500 0.02300  0.01340  0.00860  278 VAL A C   
4149 O O   . VAL A 273 ? 0.14280 0.27110 0.14290 0.00550  0.00590  -0.00170 278 VAL A O   
4150 C CB  . VAL A 273 ? 0.16590 0.26660 0.19090 0.00980  0.02870  -0.01040 278 VAL A CB  
4151 C CG1 . VAL A 273 ? 0.16410 0.26870 0.23120 0.00620  0.02610  -0.00280 278 VAL A CG1 
4152 C CG2 . VAL A 273 ? 0.19210 0.27470 0.24100 -0.00390 0.01060  0.00930  278 VAL A CG2 
4162 N N   . ILE A 274 ? 0.13560 0.24250 0.12220 0.01860  0.01170  0.01420  279 ILE A N   
4163 C CA  . ILE A 274 ? 0.14300 0.24310 0.14400 0.01880  0.00400  0.01550  279 ILE A CA  
4164 C C   . ILE A 274 ? 0.12270 0.24490 0.13860 0.02860  0.01790  0.01000  279 ILE A C   
4165 O O   . ILE A 274 ? 0.13510 0.23760 0.13300 0.01950  0.00720  0.00690  279 ILE A O   
4166 C CB  . ILE A 274 ? 0.14270 0.24250 0.12640 0.01810  0.01810  0.00830  279 ILE A CB  
4167 C CG1 . ILE A 274 ? 0.13560 0.23920 0.12420 0.00120  0.00860  0.00730  279 ILE A CG1 
4168 C CG2 . ILE A 274 ? 0.15060 0.25580 0.12220 0.01750  0.00880  0.01850  279 ILE A CG2 
4169 C CD1 . ILE A 274 ? 0.14260 0.24230 0.14530 -0.00260 0.00350  0.00200  279 ILE A CD1 
4181 N N   . ALA A 275 ? 0.12160 0.26330 0.13920 0.01410  0.00840  0.01060  280 ALA A N   
4182 C CA  . ALA A 275 ? 0.13210 0.27330 0.14110 0.00880  0.02340  0.00920  280 ALA A CA  
4183 C C   . ALA A 275 ? 0.13600 0.27730 0.13290 0.00780  0.02310  -0.00080 280 ALA A C   
4184 O O   . ALA A 275 ? 0.15230 0.26680 0.12170 0.01170  0.01660  -0.00210 280 ALA A O   
4185 C CB  . ALA A 275 ? 0.12800 0.27690 0.15800 0.00060  0.02060  -0.00430 280 ALA A CB  
4191 N N   . ALA A 276 ? 0.12850 0.28140 0.12700 0.01270  0.02260  -0.00340 281 ALA A N   
4192 C CA  . ALA A 276 ? 0.14050 0.28680 0.11980 0.00870  0.00470  -0.00540 281 ALA A CA  
4193 C C   . ALA A 276 ? 0.14720 0.28060 0.11680 0.00280  0.02380  -0.00950 281 ALA A C   
4194 O O   . ALA A 276 ? 0.18420 0.28150 0.11680 0.01390  0.01760  -0.01630 281 ALA A O   
4195 C CB  . ALA A 276 ? 0.15950 0.28280 0.13230 0.01250  -0.00860 0.00880  281 ALA A CB  
4201 N N   . ALA A 277 ? 0.13410 0.27600 0.13080 0.01700  0.01270  -0.01630 282 ALA A N   
4202 C CA  . ALA A 277 ? 0.12610 0.26890 0.12970 0.01380  0.01860  -0.00710 282 ALA A CA  
4203 C C   . ALA A 277 ? 0.12440 0.27110 0.12000 0.00380  0.02130  -0.01070 282 ALA A C   
4204 O O   . ALA A 277 ? 0.13520 0.26090 0.12500 0.01090  0.00930  -0.00070 282 ALA A O   
4205 C CB  . ALA A 277 ? 0.09600 0.26240 0.16300 0.00030  0.00840  -0.00780 282 ALA A CB  
4211 N N   . ALA A 278 ? 0.16010 0.27380 0.12830 0.00240  0.00910  -0.01530 283 ALA A N   
4212 C CA  . ALA A 278 ? 0.14290 0.26870 0.11760 0.00110  -0.00040 -0.00520 283 ALA A CA  
4213 C C   . ALA A 278 ? 0.15680 0.27220 0.12850 -0.01150 0.01230  0.00700  283 ALA A C   
4214 O O   . ALA A 278 ? 0.15130 0.27700 0.15080 -0.00360 0.01950  0.01380  283 ALA A O   
4215 C CB  . ALA A 278 ? 0.16950 0.27620 0.13030 0.01740  0.00130  -0.02660 283 ALA A CB  
4221 N N   A ARG A 279 ? 0.16350 0.26400 0.13330 -0.00520 0.02360  0.00880  284 ARG A N   
4222 N N   B ARG A 279 ? 0.14510 0.27140 0.12400 -0.00320 0.01210  0.00860  284 ARG A N   
4223 C CA  A ARG A 279 ? 0.17900 0.26120 0.14430 0.00200  0.04020  0.00650  284 ARG A CA  
4224 C CA  B ARG A 279 ? 0.15000 0.27580 0.13290 0.00680  0.01330  0.00680  284 ARG A CA  
4225 C C   A ARG A 279 ? 0.18470 0.26330 0.13440 0.00290  0.03390  0.01640  284 ARG A C   
4226 C C   B ARG A 279 ? 0.17700 0.27650 0.13210 0.00560  0.01180  0.02130  284 ARG A C   
4227 O O   A ARG A 279 ? 0.19680 0.26460 0.12570 0.00930  0.03480  0.01750  284 ARG A O   
4228 O O   B ARG A 279 ? 0.19460 0.28950 0.12700 0.01110  0.00370  0.02680  284 ARG A O   
4229 C CB  A ARG A 279 ? 0.19370 0.26670 0.17150 0.00550  0.06150  0.00460  284 ARG A CB  
4230 C CB  B ARG A 279 ? 0.13920 0.29440 0.16250 0.01330  0.01480  0.01620  284 ARG A CB  
4231 C CG  A ARG A 279 ? 0.22110 0.26920 0.19330 0.01500  0.08370  -0.00060 284 ARG A CG  
4232 C CG  B ARG A 279 ? 0.16710 0.30450 0.18330 0.02920  0.02130  0.01330  284 ARG A CG  
4233 C CD  A ARG A 279 ? 0.24690 0.27550 0.22790 0.02690  0.08630  -0.01030 284 ARG A CD  
4234 C CD  B ARG A 279 ? 0.16090 0.30780 0.20790 0.03510  0.02560  0.00490  284 ARG A CD  
4235 N NE  A ARG A 279 ? 0.28270 0.28640 0.25870 0.02850  0.05890  -0.01960 284 ARG A NE  
4236 N NE  B ARG A 279 ? 0.18340 0.30520 0.23030 0.03670  0.03470  0.02110  284 ARG A NE  
4237 C CZ  A ARG A 279 ? 0.30770 0.29310 0.27220 0.02900  0.05470  -0.01890 284 ARG A CZ  
4238 C CZ  B ARG A 279 ? 0.19730 0.31520 0.24350 0.02960  0.01520  0.00690  284 ARG A CZ  
4239 N NH1 A ARG A 279 ? 0.31110 0.29170 0.27900 0.03290  0.05190  -0.02200 284 ARG A NH1 
4240 N NH1 B ARG A 279 ? 0.17660 0.31490 0.22870 0.02650  0.02930  0.00090  284 ARG A NH1 
4241 N NH2 A ARG A 279 ? 0.32370 0.29840 0.28580 0.02310  0.04700  -0.01190 284 ARG A NH2 
4242 N NH2 B ARG A 279 ? 0.20960 0.32320 0.25950 0.02670  -0.01040 -0.00890 284 ARG A NH2 
4269 N N   . LEU A 280 ? 0.17200 0.26850 0.13580 -0.00220 0.02490  0.02020  285 LEU A N   
4270 C CA  . LEU A 280 ? 0.16880 0.28600 0.12940 0.00410  0.01090  0.02840  285 LEU A CA  
4271 C C   . LEU A 280 ? 0.19380 0.29450 0.13030 0.01310  0.01230  0.02150  285 LEU A C   
4272 O O   . LEU A 280 ? 0.20190 0.29800 0.14180 0.01590  0.00700  0.04110  285 LEU A O   
4273 C CB  . LEU A 280 ? 0.17370 0.28360 0.14140 0.00890  0.00970  0.01620  285 LEU A CB  
4274 C CG  . LEU A 280 ? 0.22520 0.29250 0.16670 0.00110  -0.00190 -0.00480 285 LEU A CG  
4275 C CD1 . LEU A 280 ? 0.27310 0.28870 0.19130 -0.00330 0.00800  -0.00140 285 LEU A CD1 
4276 C CD2 . LEU A 280 ? 0.23940 0.30190 0.16150 -0.00650 0.02890  -0.04240 285 LEU A CD2 
4289 N N   . ALA A 281 ? 0.17190 0.30130 0.11040 0.00260  0.00830  0.00990  286 ALA A N   
4290 C CA  . ALA A 281 ? 0.16470 0.30040 0.12580 0.00940  0.00260  -0.00120 286 ALA A CA  
4291 C C   . ALA A 281 ? 0.16910 0.29970 0.11270 0.00590  0.00100  0.01520  286 ALA A C   
4292 O O   . ALA A 281 ? 0.14690 0.29710 0.14990 -0.01070 0.00300  0.03460  286 ALA A O   
4293 C CB  . ALA A 281 ? 0.16470 0.29500 0.14600 0.00710  0.00460  0.01540  286 ALA A CB  
4299 N N   . LEU A 282 ? 0.18180 0.29970 0.14220 -0.00080 -0.01300 0.00790  287 LEU A N   
4300 C CA  . LEU A 282 ? 0.18470 0.30810 0.16390 -0.01820 -0.00200 -0.00130 287 LEU A CA  
4301 C C   . LEU A 282 ? 0.17860 0.32240 0.16350 -0.01760 0.01130  0.01780  287 LEU A C   
4302 O O   . LEU A 282 ? 0.17490 0.32500 0.16860 -0.01520 0.01880  0.01740  287 LEU A O   
4303 C CB  . LEU A 282 ? 0.19750 0.30920 0.20530 -0.01190 -0.00860 -0.00970 287 LEU A CB  
4304 C CG  . LEU A 282 ? 0.23970 0.31120 0.22860 0.00530  -0.03220 -0.01940 287 LEU A CG  
4305 C CD1 . LEU A 282 ? 0.24820 0.31380 0.25540 0.00960  -0.05560 -0.01820 287 LEU A CD1 
4306 C CD2 . LEU A 282 ? 0.26840 0.31970 0.23430 0.01000  -0.02870 -0.02410 287 LEU A CD2 
4318 N N   . GLU A 283 ? 0.16790 0.32180 0.16260 -0.00900 0.02690  0.02050  288 GLU A N   
4319 C CA  . GLU A 283 ? 0.19740 0.33180 0.16470 -0.01050 0.04830  0.02730  288 GLU A CA  
4320 C C   . GLU A 283 ? 0.20820 0.32840 0.15830 0.00250  0.02770  0.03040  288 GLU A C   
4321 O O   . GLU A 283 ? 0.21670 0.33780 0.14980 -0.01290 0.02840  0.02930  288 GLU A O   
4322 C CB  . GLU A 283 ? 0.23960 0.35200 0.16720 -0.01130 0.05030  0.01480  288 GLU A CB  
4323 C CG  . GLU A 283 ? 0.32250 0.37910 0.25060 -0.00010 0.02970  0.00520  288 GLU A CG  
4324 C CD  . GLU A 283 ? 0.38310 0.40250 0.33180 0.01480  -0.00910 -0.02650 288 GLU A CD  
4325 O OE1 . GLU A 283 ? 0.40820 0.41010 0.39410 0.03400  -0.02220 -0.03510 288 GLU A OE1 
4326 O OE2 . GLU A 283 ? 0.40280 0.41790 0.37770 0.00710  -0.02690 -0.04450 288 GLU A OE2 
4333 N N   . GLY A 284 ? 0.21220 0.32650 0.14560 0.00960  0.01890  0.04350  289 GLY A N   
4334 C CA  . GLY A 284 ? 0.21660 0.32740 0.13900 0.00770  0.00450  0.02280  289 GLY A CA  
4335 C C   . GLY A 284 ? 0.20460 0.32020 0.13750 0.01400  0.02350  0.03160  289 GLY A C   
4336 O O   . GLY A 284 ? 0.23880 0.34150 0.14920 0.01590  -0.00780 0.02920  289 GLY A O   
4340 N N   . LEU A 285 ? 0.19690 0.30700 0.14230 -0.01610 0.00720  0.04490  290 LEU A N   
4341 C CA  . LEU A 285 ? 0.19920 0.30390 0.14340 -0.03680 0.01270  0.04100  290 LEU A CA  
4342 C C   . LEU A 285 ? 0.20190 0.32470 0.17600 -0.05690 0.02440  0.02520  290 LEU A C   
4343 O O   . LEU A 285 ? 0.21320 0.33240 0.19000 -0.04160 0.03960  0.01860  290 LEU A O   
4344 C CB  . LEU A 285 ? 0.17030 0.28250 0.15600 -0.02830 0.01140  0.03430  290 LEU A CB  
4345 C CG  . LEU A 285 ? 0.15540 0.28000 0.17130 -0.02940 0.01420  0.02800  290 LEU A CG  
4346 C CD1 . LEU A 285 ? 0.17510 0.27550 0.15590 -0.02390 0.02580  0.04520  290 LEU A CD1 
4347 C CD2 . LEU A 285 ? 0.17400 0.28040 0.19110 -0.02530 0.01340  0.03620  290 LEU A CD2 
4359 N N   . GLY A 286 ? 0.20560 0.33650 0.19800 -0.06340 0.05660  0.02790  291 GLY A N   
4360 C CA  . GLY A 286 ? 0.21060 0.35510 0.21780 -0.06470 0.04960  0.03380  291 GLY A CA  
4361 C C   . GLY A 286 ? 0.19730 0.37990 0.23790 -0.06430 0.05430  0.02800  291 GLY A C   
4362 O O   . GLY A 286 ? 0.23710 0.39550 0.26000 -0.07410 0.05310  0.01980  291 GLY A O   
4366 N N   . VAL A 287 ? 0.18650 0.38030 0.22540 -0.04330 0.03510  0.00210  292 VAL A N   
4367 C CA  . VAL A 287 ? 0.19620 0.38020 0.28380 -0.01590 0.03110  -0.01200 292 VAL A CA  
4368 C C   . VAL A 287 ? 0.19460 0.37360 0.33600 -0.00150 0.04450  -0.01270 292 VAL A C   
4369 O O   . VAL A 287 ? 0.19520 0.37320 0.37830 0.00320  0.04140  -0.01760 292 VAL A O   
4370 C CB  . VAL A 287 ? 0.21830 0.38350 0.26850 -0.01420 0.00190  -0.03420 292 VAL A CB  
4371 C CG1 . VAL A 287 ? 0.23320 0.38380 0.29150 -0.00990 -0.01720 -0.03230 292 VAL A CG1 
4372 C CG2 . VAL A 287 ? 0.24090 0.38840 0.25420 -0.01340 0.01930  -0.04660 292 VAL A CG2 
4382 N N   . ASN A 288 ? 0.19760 0.37160 0.33000 0.01300  0.06670  -0.02420 293 ASN A N   
4383 C CA  . ASN A 288 ? 0.22380 0.37170 0.31440 0.00680  0.05850  -0.03420 293 ASN A CA  
4384 C C   . ASN A 288 ? 0.27600 0.38110 0.32270 0.00730  0.02340  -0.04230 293 ASN A C   
4385 O O   . ASN A 288 ? 0.31770 0.38280 0.31050 -0.01270 0.02580  -0.03080 293 ASN A O   
4386 C CB  . ASN A 288 ? 0.20260 0.36810 0.30870 -0.00050 0.03760  -0.04180 293 ASN A CB  
4387 C CG  . ASN A 288 ? 0.19000 0.35840 0.28820 -0.00460 0.01660  -0.05750 293 ASN A CG  
4388 O OD1 . ASN A 288 ? 0.24510 0.36490 0.31680 -0.01240 0.00290  -0.07940 293 ASN A OD1 
4389 N ND2 . ASN A 288 ? 0.15920 0.34650 0.24160 -0.00680 0.00440  -0.05440 293 ASN A ND2 
4396 N N   . GLY A 289 ? 0.29090 0.39050 0.34260 0.03020  -0.00510 -0.06220 294 GLY A N   
4397 C CA  . GLY A 289 ? 0.30900 0.40020 0.34890 0.05140  -0.00730 -0.08820 294 GLY A CA  
4398 C C   . GLY A 289 ? 0.28800 0.40940 0.35600 0.05450  0.02430  -0.10200 294 GLY A C   
4399 O O   . GLY A 289 ? 0.27790 0.41540 0.38400 0.00850  0.04990  -0.06380 294 GLY A O   
4403 S S   . SO4 B .   ? 0.65940 0.74380 0.69560 0.02020  0.03210  -0.11010 301 SO4 A S   
4404 O O1  . SO4 B .   ? 0.65600 0.74070 0.69310 0.01480  0.03020  -0.10380 301 SO4 A O1  
4405 O O2  . SO4 B .   ? 0.66090 0.74050 0.69780 0.02150  0.02810  -0.10410 301 SO4 A O2  
4406 O O3  . SO4 B .   ? 0.67210 0.74750 0.70640 0.01810  0.03450  -0.10860 301 SO4 A O3  
4407 O O4  . SO4 B .   ? 0.66820 0.74650 0.70730 0.02010  0.03340  -0.10630 301 SO4 A O4  
4408 S S   . SO4 C .   ? 0.29820 0.39650 0.37080 0.06130  0.00430  0.04390  302 SO4 A S   
4409 O O1  . SO4 C .   ? 0.35530 0.40930 0.42830 0.04190  0.00460  0.00130  302 SO4 A O1  
4410 O O2  . SO4 C .   ? 0.30340 0.38830 0.30740 0.08610  0.00310  0.09300  302 SO4 A O2  
4411 O O3  . SO4 C .   ? 0.23120 0.36250 0.32200 0.08480  -0.00430 0.04390  302 SO4 A O3  
4412 O O4  . SO4 C .   ? 0.31000 0.41270 0.39730 0.06820  0.00750  0.06680  302 SO4 A O4  
4413 C C1  A O2F D .   ? 0.33030 0.26330 0.34430 0.00100  -0.05350 0.02690  303 O2F A C1  
4414 C C2  A O2F D .   ? 0.32920 0.26350 0.35100 -0.00150 -0.05540 0.02780  303 O2F A C2  
4415 C C3  A O2F D .   ? 0.27670 0.25860 0.29030 0.00560  -0.05950 0.02200  303 O2F A C3  
4416 C C4  A O2F D .   ? 0.25330 0.25370 0.24910 -0.00390 -0.05340 0.02430  303 O2F A C4  
4417 C C5  A O2F D .   ? 0.25530 0.25720 0.25650 0.00030  -0.06450 0.02810  303 O2F A C5  
4418 C C7  A O2F D .   ? 0.16210 0.24200 0.12340 -0.00650 -0.02340 0.00430  303 O2F A C7  
4419 C C9  A O2F D .   ? 0.23030 0.27370 0.13960 0.01070  -0.00270 0.01030  303 O2F A C9  
4420 C C11 A O2F D .   ? 0.14670 0.23130 0.15200 -0.01430 -0.01710 0.00610  303 O2F A C11 
4421 C C15 A O2F D .   ? 0.13590 0.23420 0.14310 -0.00100 -0.00580 0.00620  303 O2F A C15 
4422 C C16 A O2F D .   ? 0.14570 0.23740 0.14100 0.00720  -0.00290 0.01170  303 O2F A C16 
4423 N N   A O2F D .   ? 0.32130 0.26260 0.33830 -0.00550 -0.05530 0.02850  303 O2F A N   
4424 C C   A O2F D .   ? 0.30180 0.26580 0.32440 -0.00010 -0.06150 0.02760  303 O2F A C   
4425 O O   A O2F D .   ? 0.29850 0.27170 0.34380 -0.00330 -0.06630 0.02620  303 O2F A O   
4426 C C10 A O2F D .   ? 0.13660 0.23350 0.15780 -0.00950 -0.03650 0.01200  303 O2F A C10 
4427 C C12 A O2F D .   ? 0.17200 0.23150 0.13970 -0.00810 -0.02400 0.00080  303 O2F A C12 
4428 C C13 A O2F D .   ? 0.16030 0.22840 0.12910 -0.01280 0.00720  0.00280  303 O2F A C13 
4429 C C14 A O2F D .   ? 0.16360 0.23170 0.16500 -0.02570 0.01520  -0.01410 303 O2F A C14 
4430 C C6  A O2F D .   ? 0.23420 0.24970 0.22260 -0.00740 -0.05380 0.02810  303 O2F A C6  
4431 C C8  A O2F D .   ? 0.19150 0.25620 0.14030 -0.00160 -0.00640 0.00550  303 O2F A C8  
4432 N N1  A O2F D .   ? 0.27210 0.25760 0.27790 0.00760  -0.05800 0.01520  303 O2F A N1  
4433 N N2  A O2F D .   ? 0.17480 0.24550 0.15760 -0.00550 -0.02490 0.00430  303 O2F A N2  
4434 O O1  A O2F D .   ? 0.23170 0.27540 0.12360 -0.01480 0.02400  0.02300  303 O2F A O1  
4435 O O2  A O2F D .   ? 0.22180 0.29340 0.12730 0.02870  -0.04800 -0.00950 303 O2F A O2  
4436 O O3  A O2F D .   ? 0.20030 0.23940 0.15330 0.00820  -0.02930 0.00670  303 O2F A O3  
4437 O O4  A O2F D .   ? 0.18280 0.22920 0.10550 -0.01470 -0.01610 -0.00540 303 O2F A O4  
4438 S S   A O2F D .   ? 0.17910 0.23510 0.16420 -0.02450 -0.04230 0.01180  303 O2F A S   
4464 C C1  B MER E .   ? 0.19480 0.25320 0.12170 0.01250  -0.01620 0.00920  304 MER A C1  
4465 C C2  B MER E .   ? 0.25710 0.33620 0.31460 0.03640  0.05080  -0.01030 304 MER A C2  
4466 C C3  B MER E .   ? 0.19900 0.27760 0.17040 0.02140  -0.00090 0.01640  304 MER A C3  
4467 C C4  B MER E .   ? 0.21450 0.29910 0.23970 0.03090  0.03250  0.03130  304 MER A C4  
4468 C C5  B MER E .   ? 0.27190 0.32940 0.30440 0.03620  0.06120  0.01330  304 MER A C5  
4469 O O6  B MER E .   ? 0.22600 0.25730 0.09070 0.01820  -0.02760 0.01610  304 MER A O6  
4470 C C7  B MER E .   ? 0.21710 0.28380 0.18030 0.02930  -0.01190 0.01890  304 MER A C7  
4471 O O8  B MER E .   ? 0.22470 0.28200 0.17410 0.03630  -0.01970 0.01790  304 MER A O8  
4472 C C9  B MER E .   ? 0.22420 0.29330 0.21220 0.02000  -0.02910 0.00750  304 MER A C9  
4473 N N10 B MER E .   ? 0.22500 0.30960 0.28490 0.04170  0.05980  0.02990  304 MER A N10 
4474 C C11 B MER E .   ? 0.32620 0.34300 0.30680 0.03480  0.01850  0.02800  304 MER A C11 
4475 O O12 B MER E .   ? 0.35280 0.35460 0.31610 0.02350  0.00660  0.02920  304 MER A O12 
4476 O O13 B MER E .   ? 0.34310 0.34540 0.30040 0.02900  -0.01640 0.03870  304 MER A O13 
4477 S S14 B MER E .   ? 0.27660 0.36880 0.36890 0.04010  0.02130  -0.05150 304 MER A S14 
4478 C C15 B MER E .   ? 0.35990 0.41050 0.43390 0.03290  0.00130  -0.04350 304 MER A C15 
4479 C C16 B MER E .   ? 0.40780 0.43420 0.46870 0.02260  -0.00440 -0.03680 304 MER A C16 
4480 C C17 B MER E .   ? 0.44130 0.45280 0.49820 0.01750  -0.00190 -0.03460 304 MER A C17 
4481 C C18 B MER E .   ? 0.24040 0.31270 0.27150 0.02940  0.03040  0.01560  304 MER A C18 
4482 N N19 B MER E .   ? 0.42130 0.44120 0.48550 0.02310  -0.00240 -0.03890 304 MER A N19 
4483 C C20 B MER E .   ? 0.24430 0.30410 0.27020 0.02090  0.00980  0.02610  304 MER A C20 
4484 C C21 B MER E .   ? 0.39260 0.42570 0.46590 0.02660  -0.00400 -0.03710 304 MER A C21 
4485 C C22 B MER E .   ? 0.48520 0.48180 0.53750 0.00890  0.00460  -0.02750 304 MER A C22 
4486 N N23 B MER E .   ? 0.50490 0.50060 0.55220 0.00910  0.00810  -0.01800 304 MER A N23 
4487 O O24 B MER E .   ? 0.49700 0.48830 0.55400 -0.00010 0.00390  -0.02640 304 MER A O24 
4488 C C25 B MER E .   ? 0.51020 0.50520 0.55570 0.00730  0.00880  -0.01730 304 MER A C25 
4489 C C26 B MER E .   ? 0.51490 0.50720 0.55890 0.00450  0.00460  -0.01630 304 MER A C26 
4515 S S   . SO4 F .   ? 0.56190 0.57380 0.42870 0.05260  0.21720  0.08660  305 SO4 A S   
4516 O O1  . SO4 F .   ? 0.59290 0.58910 0.48930 0.03220  0.19470  0.06980  305 SO4 A O1  
4517 O O2  . SO4 F .   ? 0.58630 0.57230 0.44290 0.07390  0.23130  0.08570  305 SO4 A O2  
4518 O O3  . SO4 F .   ? 0.55610 0.55990 0.42390 0.04570  0.22550  0.07830  305 SO4 A O3  
4519 O O4  . SO4 F .   ? 0.59130 0.57700 0.40260 0.05030  0.23280  0.08290  305 SO4 A O4  
4520 O O   . HOH G .   ? 0.38400 0.42880 0.51990 0.01570  0.09590  0.07160  401 HOH A O   
4521 O O   A HOH G .   ? 0.35560 0.28640 0.28850 0.02720  0.10510  -0.00080 402 HOH A O   
4522 O O   . HOH G .   ? 0.29030 0.41070 0.45560 0.03980  0.06470  0.23850  403 HOH A O   
4523 O O   . HOH G .   ? 0.31380 0.60730 0.55860 -0.04770 -0.00600 0.09090  404 HOH A O   
4524 O O   . HOH G .   ? 0.47790 0.56790 0.42310 -0.12830 0.00990  -0.05940 405 HOH A O   
4525 O O   . HOH G .   ? 0.49640 0.35370 0.33420 0.06120  0.11820  0.09310  406 HOH A O   
4526 O O   . HOH G .   ? 0.57850 0.65560 0.52880 0.02390  -0.07000 0.08180  407 HOH A O   
4527 O O   . HOH G .   ? 0.60440 0.61120 0.53880 0.01040  -0.04030 -0.13510 408 HOH A O   
4528 O O   . HOH G .   ? 0.55370 0.54890 0.49130 0.12120  -0.06110 -0.10320 409 HOH A O   
4529 O O   . HOH G .   ? 0.56900 0.43740 0.57080 0.06550  0.08370  0.09890  410 HOH A O   
4530 O O   . HOH G .   ? 0.31140 0.55880 0.44970 -0.00310 0.03450  -0.06860 411 HOH A O   
4531 O O   . HOH G .   ? 0.63830 0.80010 0.67320 0.05670  -0.11820 -0.00910 412 HOH A O   
4532 O O   . HOH G .   ? 0.25990 0.30060 0.24490 0.00550  0.03040  0.00920  413 HOH A O   
4533 O O   . HOH G .   ? 0.53480 0.36390 0.37860 -0.16510 0.00060  0.03350  414 HOH A O   
4534 O O   . HOH G .   ? 0.48060 0.44350 0.26970 0.13650  0.08670  0.02630  415 HOH A O   
4535 O O   . HOH G .   ? 0.61260 0.63090 0.59590 -0.01460 -0.04570 0.08170  416 HOH A O   
4536 O O   . HOH G .   ? 0.58290 0.58290 0.46160 0.04110  -0.06450 -0.07760 417 HOH A O   
4537 O O   . HOH G .   ? 0.33600 0.43010 0.52910 0.00460  0.10900  -0.02510 418 HOH A O   
4538 O O   . HOH G .   ? 0.30660 0.43220 0.78440 -0.13400 -0.07280 0.15780  419 HOH A O   
4539 O O   . HOH G .   ? 0.56820 0.52240 0.60440 -0.09530 -0.03870 -0.09750 420 HOH A O   
4540 O O   . HOH G .   ? 0.10430 0.09590 0.15820 0.04710  0.01860  0.00500  421 HOH A O   
4541 O O   . HOH G .   ? 0.36140 0.42750 0.35670 -0.01430 -0.08530 -0.04070 422 HOH A O   
4542 O O   . HOH G .   ? 0.23150 0.46890 0.21400 0.00350  0.03670  0.07370  423 HOH A O   
4543 O O   . HOH G .   ? 0.40400 0.37700 0.36300 -0.04100 0.00470  0.00680  424 HOH A O   
4544 O O   . HOH G .   ? 0.15100 0.22540 0.12510 -0.01770 0.00680  0.02730  425 HOH A O   
4545 O O   . HOH G .   ? 0.34130 0.48890 0.38330 0.02680  -0.04470 0.01450  426 HOH A O   
4546 O O   . HOH G .   ? 0.38780 0.36010 0.48400 -0.10410 0.02830  0.04320  427 HOH A O   
4547 O O   . HOH G .   ? 0.52450 0.64450 0.76310 -0.06620 0.21560  0.03880  428 HOH A O   
4548 O O   A HOH G .   ? 0.37950 0.34150 0.23610 -0.00630 0.06920  0.08410  429 HOH A O   
4549 O O   . HOH G .   ? 0.34940 0.50850 0.57320 0.01360  -0.13050 0.12230  430 HOH A O   
4550 O O   . HOH G .   ? 0.44180 0.34770 0.25060 -0.00290 -0.03940 0.09060  431 HOH A O   
4551 O O   . HOH G .   ? 0.52120 0.46450 0.50060 0.02040  -0.07110 0.03360  432 HOH A O   
4552 O O   . HOH G .   ? 0.58650 0.40090 0.38270 -0.15160 -0.20760 0.12580  433 HOH A O   
4553 O O   . HOH G .   ? 0.52470 0.68400 0.58540 -0.09910 -0.00490 -0.10660 434 HOH A O   
4554 O O   . HOH G .   ? 0.19410 0.26140 0.15310 0.00040  0.01210  0.00320  435 HOH A O   
4555 O O   . HOH G .   ? 0.35160 0.42620 0.32470 -0.05570 -0.00850 0.03220  436 HOH A O   
4556 O O   . HOH G .   ? 0.14000 0.26050 0.15030 -0.03310 0.00920  -0.00440 437 HOH A O   
4557 O O   . HOH G .   ? 0.58540 0.35320 0.22080 0.05240  0.02260  0.00010  438 HOH A O   
4558 O O   . HOH G .   ? 0.58530 0.35830 0.27430 -0.00370 -0.06580 -0.03750 439 HOH A O   
4559 O O   . HOH G .   ? 0.31220 0.40660 0.25010 0.02870  0.06670  0.04580  440 HOH A O   
4560 O O   . HOH G .   ? 0.57060 0.68170 0.62620 0.05230  0.13390  -0.00240 441 HOH A O   
4561 O O   . HOH G .   ? 0.19540 0.26120 0.19880 0.01090  -0.02920 -0.00490 442 HOH A O   
4562 O O   . HOH G .   ? 0.17760 0.50200 0.47210 -0.03660 -0.02480 -0.10720 443 HOH A O   
4563 O O   . HOH G .   ? 0.87300 0.93900 0.93180 -0.02860 -0.01620 0.08120  444 HOH A O   
4564 O O   . HOH G .   ? 0.21110 0.28950 0.24560 0.00260  -0.03540 -0.01040 445 HOH A O   
4565 O O   . HOH G .   ? 0.29480 0.39440 0.34880 -0.14940 0.01370  0.05180  446 HOH A O   
4566 O O   . HOH G .   ? 0.26760 0.29740 0.40000 -0.00260 -0.11770 -0.04710 447 HOH A O   
4567 O O   . HOH G .   ? 0.33830 0.61670 0.41340 0.04560  0.09290  -0.04270 448 HOH A O   
4568 O O   . HOH G .   ? 0.17200 0.26430 0.14500 -0.01460 0.00140  -0.00540 449 HOH A O   
4569 O O   . HOH G .   ? 0.17640 0.54990 0.25540 -0.08640 -0.00030 -0.01280 450 HOH A O   
4570 O O   . HOH G .   ? 0.34700 0.53990 0.35230 -0.03060 -0.11440 0.05070  451 HOH A O   
4571 O O   . HOH G .   ? 0.55070 0.50030 0.51730 -0.11940 -0.14230 -0.05450 452 HOH A O   
4572 O O   . HOH G .   ? 0.34330 0.25210 0.22990 0.02380  -0.07020 -0.03030 453 HOH A O   
4573 O O   . HOH G .   ? 0.13710 0.25730 0.11180 -0.00840 0.01060  -0.00700 454 HOH A O   
4574 O O   . HOH G .   ? 0.37500 0.43530 0.26020 -0.02670 0.02500  -0.09340 455 HOH A O   
4575 O O   . HOH G .   ? 0.16100 0.42000 0.23760 0.03300  -0.00590 0.02960  456 HOH A O   
4576 O O   . HOH G .   ? 0.47800 0.55670 0.53950 0.14110  0.04340  0.16900  457 HOH A O   
4577 O O   . HOH G .   ? 0.36700 0.42970 0.33510 -0.03380 0.02730  -0.09140 458 HOH A O   
4578 O O   . HOH G .   ? 0.54180 0.49650 0.44440 0.00840  -0.15000 0.22040  459 HOH A O   
4579 O O   . HOH G .   ? 0.50150 0.41600 0.44420 -0.01990 -0.17580 0.14580  460 HOH A O   
4580 O O   . HOH G .   ? 0.16520 0.36520 0.47390 -0.02020 -0.01890 0.15550  461 HOH A O   
4581 O O   . HOH G .   ? 0.16120 0.35670 0.29410 -0.06150 0.03770  -0.06290 462 HOH A O   
4582 O O   . HOH G .   ? 0.18020 0.26500 0.16420 -0.00800 0.01960  -0.01090 463 HOH A O   
4583 O O   . HOH G .   ? 0.57170 0.35480 0.33150 -0.09720 -0.03320 0.04810  464 HOH A O   
4584 O O   . HOH G .   ? 0.32760 0.34230 0.19110 -0.11310 -0.01650 -0.01660 465 HOH A O   
4585 O O   . HOH G .   ? 0.17930 0.36240 0.20400 -0.03090 0.00610  0.05500  466 HOH A O   
4586 O O   . HOH G .   ? 0.19920 0.40020 0.23960 0.00020  0.00200  -0.01370 467 HOH A O   
4587 O O   . HOH G .   ? 0.23460 0.31770 0.23190 0.07480  -0.01350 -0.04560 468 HOH A O   
4588 O O   . HOH G .   ? 0.29810 0.42610 0.30350 -0.04050 0.10490  -0.01220 469 HOH A O   
4589 O O   . HOH G .   ? 0.53460 0.32970 0.46890 -0.04090 -0.00360 -0.10520 470 HOH A O   
4590 O O   . HOH G .   ? 0.21850 0.29920 0.21420 0.00280  -0.00170 0.03380  471 HOH A O   
4591 O O   . HOH G .   ? 0.34330 0.53710 0.56840 0.16400  -0.15820 0.01890  472 HOH A O   
4592 O O   . HOH G .   ? 0.25830 0.41640 0.69000 -0.03230 0.13540  0.09720  473 HOH A O   
4593 O O   . HOH G .   ? 0.16390 0.32900 0.19150 -0.02430 -0.01220 -0.01010 474 HOH A O   
4594 O O   . HOH G .   ? 0.38580 0.30440 0.21630 0.05820  -0.06630 0.01440  475 HOH A O   
4595 O O   . HOH G .   ? 0.27460 0.49900 0.40350 -0.01060 -0.04330 -0.08420 476 HOH A O   
4596 O O   . HOH G .   ? 0.28260 0.37340 0.25840 0.05150  0.12100  0.08600  477 HOH A O   
4597 O O   . HOH G .   ? 0.14660 0.30120 0.27860 0.00840  0.00590  -0.00230 478 HOH A O   
4598 O O   A HOH G .   ? 0.52510 0.43160 0.33990 0.02190  -0.01500 0.00170  479 HOH A O   
4599 O O   . HOH G .   ? 0.33650 0.40920 0.39150 -0.04090 0.03070  0.03060  480 HOH A O   
4600 O O   . HOH G .   ? 0.55440 0.52340 0.51040 0.01960  -0.14890 -0.11760 481 HOH A O   
4601 O O   . HOH G .   ? 0.15040 0.26910 0.17460 -0.00950 -0.00760 0.00430  482 HOH A O   
4602 O O   . HOH G .   ? 0.51490 0.22380 0.20000 -0.04590 0.04900  0.02380  483 HOH A O   
4603 O O   . HOH G .   ? 0.76480 0.72920 0.63030 0.03720  -0.03090 0.09450  484 HOH A O   
4604 O O   . HOH G .   ? 0.60410 0.60200 0.52640 -0.05020 -0.18370 -0.03680 485 HOH A O   
4605 O O   . HOH G .   ? 0.64990 0.67080 0.70590 -0.14650 -0.00640 0.02510  486 HOH A O   
4606 O O   . HOH G .   ? 0.28080 0.33190 0.29760 -0.07360 -0.00080 -0.01080 487 HOH A O   
4607 O O   . HOH G .   ? 0.14190 0.34930 0.15030 -0.01400 -0.00720 0.03980  488 HOH A O   
4608 O O   . HOH G .   ? 0.41660 0.56610 0.55810 0.18120  -0.12880 -0.16380 489 HOH A O   
4609 O O   . HOH G .   ? 0.26320 0.45260 0.27370 -0.11550 0.05770  -0.04730 490 HOH A O   
4610 O O   . HOH G .   ? 0.37740 0.42920 0.32720 -0.05870 0.05440  -0.06270 491 HOH A O   
4611 O O   . HOH G .   ? 0.28230 0.35160 0.16400 0.01800  0.03170  0.03130  492 HOH A O   
4612 O O   . HOH G .   ? 0.36090 0.36080 0.48050 0.00930  -0.13830 -0.07260 493 HOH A O   
4613 O O   . HOH G .   ? 0.35610 0.54960 0.40090 -0.10610 0.02610  0.05250  494 HOH A O   
4614 O O   . HOH G .   ? 0.31760 0.36290 0.44430 -0.05950 0.11900  -0.05770 495 HOH A O   
4615 O O   . HOH G .   ? 0.26810 0.40570 0.42590 0.07410  -0.01620 0.02810  496 HOH A O   
4616 O O   . HOH G .   ? 0.17210 0.32470 0.17200 0.02270  -0.02990 0.02180  497 HOH A O   
4617 O O   . HOH G .   ? 0.25630 0.41560 0.34010 0.05240  0.00340  0.08050  498 HOH A O   
4618 O O   . HOH G .   ? 0.17760 0.27730 0.14110 0.01140  -0.00270 0.00460  499 HOH A O   
4619 O O   . HOH G .   ? 0.40280 0.55150 0.37390 -0.01920 0.00390  -0.06650 500 HOH A O   
4620 O O   . HOH G .   ? 0.21760 0.35060 0.21300 0.03510  0.04040  0.01150  501 HOH A O   
4621 O O   . HOH G .   ? 0.52390 0.38930 0.36270 0.05560  0.00930  0.06080  502 HOH A O   
4622 O O   . HOH G .   ? 0.13660 0.27950 0.13620 0.02390  0.01640  0.03140  503 HOH A O   
4623 O O   . HOH G .   ? 0.37280 0.41360 0.33160 -0.10050 -0.02270 0.04810  504 HOH A O   
4624 O O   . HOH G .   ? 0.48780 0.49250 0.38990 0.00710  -0.15670 0.12210  505 HOH A O   
4625 O O   . HOH G .   ? 0.38520 0.39060 0.35270 0.09020  -0.03620 -0.10040 506 HOH A O   
4626 O O   . HOH G .   ? 0.32030 0.30870 0.52080 -0.01380 0.03090  -0.02990 507 HOH A O   
4627 O O   . HOH G .   ? 0.52990 0.58770 0.45680 0.04870  -0.01900 -0.09430 508 HOH A O   
4628 O O   . HOH G .   ? 0.35770 0.43670 0.49420 0.03620  -0.06330 0.02670  509 HOH A O   
4629 O O   . HOH G .   ? 0.30300 0.51700 0.26860 0.11220  0.03900  -0.01310 510 HOH A O   
4630 O O   . HOH G .   ? 0.17640 0.21680 0.28930 0.00040  0.03720  0.02350  511 HOH A O   
4631 O O   . HOH G .   ? 0.22330 0.36550 0.31370 -0.00700 -0.08140 0.04510  512 HOH A O   
4632 O O   . HOH G .   ? 0.26210 0.31620 0.38010 0.10700  -0.02230 -0.10570 513 HOH A O   
4633 O O   . HOH G .   ? 0.45780 0.49020 0.51560 -0.13230 0.06960  -0.09680 514 HOH A O   
4634 O O   . HOH G .   ? 0.58710 0.55880 0.48650 0.11410  -0.13710 0.03460  515 HOH A O   
4635 O O   . HOH G .   ? 0.31290 0.48890 0.51000 -0.15140 -0.05320 0.09260  516 HOH A O   
4636 O O   . HOH G .   ? 0.39440 0.40190 0.41240 0.06460  -0.22210 0.02350  517 HOH A O   
4637 O O   . HOH G .   ? 0.62780 0.35960 0.36590 0.01470  0.23270  0.09690  518 HOH A O   
4638 O O   . HOH G .   ? 0.54250 0.55450 0.59200 -0.15910 -0.02330 0.11560  519 HOH A O   
4639 O O   . HOH G .   ? 0.37360 0.37220 0.50070 0.02840  0.09490  -0.12350 520 HOH A O   
4640 O O   . HOH G .   ? 0.48640 0.43050 0.56260 0.02460  -0.15130 -0.06840 521 HOH A O   
4641 O O   . HOH G .   ? 0.37640 0.41120 0.40150 -0.06010 -0.20700 0.12460  522 HOH A O   
4642 O O   . HOH G .   ? 0.21580 0.33070 0.38760 -0.01210 0.07820  0.05130  523 HOH A O   
4643 O O   . HOH G .   ? 0.60920 0.50900 0.70310 0.09900  0.01140  0.09850  524 HOH A O   
4644 O O   . HOH G .   ? 0.20540 0.35340 0.15730 -0.03250 -0.04660 0.01680  525 HOH A O   
4645 O O   . HOH G .   ? 0.22200 0.45370 0.30670 -0.00880 0.00320  0.04040  526 HOH A O   
4646 O O   . HOH G .   ? 0.29070 0.46640 0.47470 -0.05510 -0.08140 -0.09420 527 HOH A O   
4647 O O   . HOH G .   ? 0.15930 0.28130 0.14150 -0.03220 0.03830  -0.01310 528 HOH A O   
4648 O O   . HOH G .   ? 0.34710 0.47610 0.23320 0.08280  0.00230  -0.01320 529 HOH A O   
4649 O O   . HOH G .   ? 0.32240 0.39880 0.24990 -0.08070 0.01240  0.02900  530 HOH A O   
4650 O O   . HOH G .   ? 0.25310 0.61530 0.37880 -0.00040 -0.03180 0.03070  531 HOH A O   
4651 O O   . HOH G .   ? 0.20900 0.26040 0.24310 0.02700  -0.00020 0.00250  532 HOH A O   
4652 O O   . HOH G .   ? 0.22980 0.34600 0.33770 -0.05050 0.02400  0.02040  533 HOH A O   
4653 O O   . HOH G .   ? 0.45840 0.28920 0.42240 -0.01300 -0.11680 -0.07320 534 HOH A O   
4654 O O   . HOH G .   ? 0.49740 0.34900 0.29820 -0.03970 -0.15230 0.03060  535 HOH A O   
4655 O O   . HOH G .   ? 0.36750 0.30440 0.55640 -0.00940 0.20880  -0.09570 536 HOH A O   
4656 O O   . HOH G .   ? 0.16400 0.34550 0.16580 -0.00990 -0.00300 0.00370  537 HOH A O   
4657 O O   . HOH G .   ? 0.33130 0.40320 0.56900 -0.07030 0.05190  -0.12160 538 HOH A O   
4658 O O   . HOH G .   ? 0.39570 0.44660 0.26580 0.11990  0.05140  -0.00320 539 HOH A O   
4659 O O   . HOH G .   ? 0.19710 0.31950 0.25240 -0.01130 0.01140  0.04440  540 HOH A O   
4660 O O   . HOH G .   ? 0.42760 0.47580 0.28740 0.08900  -0.03080 0.05520  541 HOH A O   
4661 O O   . HOH G .   ? 0.38210 0.60680 0.57220 0.19870  0.17300  0.08520  542 HOH A O   
4662 O O   . HOH G .   ? 0.60510 0.51650 0.36080 -0.01520 0.06340  -0.01960 543 HOH A O   
4663 O O   . HOH G .   ? 0.30620 0.51390 0.34280 -0.06700 -0.02900 0.15850  544 HOH A O   
4664 O O   . HOH G .   ? 0.20150 0.39400 0.26770 -0.08680 -0.04520 0.00930  545 HOH A O   
4665 O O   . HOH G .   ? 0.32470 0.42590 0.33520 -0.09690 0.03400  -0.00640 546 HOH A O   
4666 O O   . HOH G .   ? 0.42140 0.51990 0.38110 -0.13810 -0.11380 -0.02080 547 HOH A O   
4667 O O   . HOH G .   ? 0.37320 0.53150 0.50990 0.07960  0.14050  -0.02960 548 HOH A O   
4668 O O   . HOH G .   ? 0.30260 0.35270 0.49620 0.00900  -0.10290 -0.07650 549 HOH A O   
4669 O O   . HOH G .   ? 0.63420 0.47250 0.59830 0.12430  0.14460  -0.03700 550 HOH A O   
4670 O O   . HOH G .   ? 0.63520 0.64470 0.66860 -0.05270 -0.14770 0.19220  551 HOH A O   
4671 O O   . HOH G .   ? 0.39490 0.38610 0.20690 -0.01800 -0.00010 -0.04510 552 HOH A O   
4672 O O   . HOH G .   ? 0.31010 0.45130 0.36400 -0.10640 0.04660  -0.07830 553 HOH A O   
4673 O O   . HOH G .   ? 0.35540 0.58180 0.26900 0.16530  0.11410  0.15060  554 HOH A O   
4674 O O   . HOH G .   ? 0.22180 0.42740 0.18980 -0.06720 0.04970  -0.03800 555 HOH A O   
4675 O O   . HOH G .   ? 0.19650 0.38430 0.17830 -0.04500 -0.00170 0.02470  556 HOH A O   
4676 O O   . HOH G .   ? 0.27730 0.40300 0.19130 0.02000  0.03890  -0.01320 557 HOH A O   
4677 O O   . HOH G .   ? 0.17350 0.30530 0.23370 0.00350  0.02960  -0.07020 558 HOH A O   
4678 O O   . HOH G .   ? 0.75120 0.76130 0.83220 0.02470  -0.03710 0.04160  559 HOH A O   
4679 O O   . HOH G .   ? 0.50370 0.45640 0.44260 0.08760  0.10640  0.02920  560 HOH A O   
4680 O O   . HOH G .   ? 0.34620 0.44670 0.36450 0.03280  0.05070  -0.07220 561 HOH A O   
4681 O O   . HOH G .   ? 0.23580 0.62030 0.37020 0.04420  -0.01790 -0.05130 562 HOH A O   
4682 O O   . HOH G .   ? 0.39310 0.49300 0.37830 0.03900  0.05910  0.02360  563 HOH A O   
4683 O O   . HOH G .   ? 0.17290 0.46020 0.38900 -0.03270 0.07870  -0.09200 564 HOH A O   
4684 O O   . HOH G .   ? 0.38510 0.63080 0.51220 0.04440  -0.11010 -0.00570 565 HOH A O   
4685 O O   . HOH G .   ? 0.63790 0.53140 0.46680 0.07010  0.06760  0.12450  566 HOH A O   
4686 O O   . HOH G .   ? 0.39790 0.43040 0.35230 0.02080  -0.01340 0.05180  567 HOH A O   
4687 O O   . HOH G .   ? 0.26240 0.56910 0.50520 -0.03540 0.08990  -0.12000 568 HOH A O   
4688 O O   . HOH G .   ? 0.73140 0.74460 0.78460 0.14950  0.02070  0.01420  569 HOH A O   
4689 O O   . HOH G .   ? 0.43110 0.27480 0.23750 -0.03240 -0.14140 -0.00280 570 HOH A O   
4690 O O   . HOH G .   ? 0.33140 0.57090 0.34560 0.01160  -0.13250 0.04440  571 HOH A O   
4691 O O   . HOH G .   ? 0.47880 0.56750 0.59780 0.10030  0.09330  0.26980  572 HOH A O   
4692 O O   . HOH G .   ? 0.13430 0.19900 0.13140 -0.01630 -0.00270 -0.01760 573 HOH A O   
4693 O O   . HOH G .   ? 0.26350 0.47190 0.33270 0.06710  0.01490  -0.04970 574 HOH A O   
4694 O O   . HOH G .   ? 0.52060 0.39990 0.49990 -0.10820 -0.19790 -0.02590 575 HOH A O   
4695 O O   . HOH G .   ? 0.37810 0.46680 0.19710 -0.02270 -0.00200 0.10330  576 HOH A O   
4696 O O   . HOH G .   ? 0.38310 0.61100 0.39090 0.07340  0.02190  0.10010  577 HOH A O   
4697 O O   C HOH G .   ? 0.58770 0.56260 0.52410 -0.04760 -0.05370 -0.02660 578 HOH A O   
4698 O O   . HOH G .   ? 0.53960 0.40780 0.39820 0.01690  -0.00400 0.02600  579 HOH A O   
4699 O O   . HOH G .   ? 0.59150 0.58550 0.46500 0.04850  -0.11090 0.12560  580 HOH A O   
4700 O O   . HOH G .   ? 0.65110 0.58480 0.56360 0.04100  -0.05050 0.01620  581 HOH A O   
4701 O O   . HOH G .   ? 0.44670 0.28650 0.59070 0.00000  0.00210  0.07290  582 HOH A O   
4702 O O   . HOH G .   ? 0.31120 0.35640 0.44970 -0.03050 0.04770  -0.03060 583 HOH A O   
4703 O O   . HOH G .   ? 0.42560 0.61820 0.39500 -0.04690 0.10030  0.00830  584 HOH A O   
4704 O O   . HOH G .   ? 0.48810 0.42160 0.22670 -0.12050 0.02060  0.02740  585 HOH A O   
4705 O O   . HOH G .   ? 0.41620 0.36510 0.43260 0.02610  -0.00470 0.06620  586 HOH A O   
4706 O O   . HOH G .   ? 0.38230 0.57720 0.29040 0.20190  0.05980  0.17120  587 HOH A O   
4707 O O   . HOH G .   ? 0.45820 0.54150 0.60150 0.05700  -0.12690 0.14320  588 HOH A O   
4708 O O   . HOH G .   ? 0.37300 0.46040 0.45390 0.04900  0.11440  0.21760  589 HOH A O   
4709 O O   . HOH G .   ? 0.59130 0.48870 0.42010 0.05790  -0.15530 -0.01300 590 HOH A O   
4710 O O   . HOH G .   ? 0.25810 0.52530 0.28910 -0.06110 0.01120  0.04010  591 HOH A O   
4711 O O   . HOH G .   ? 0.44300 0.43370 0.33530 -0.08090 0.07080  -0.07580 592 HOH A O   
4712 O O   . HOH G .   ? 0.52710 0.50020 0.50820 0.07880  -0.03300 0.07070  593 HOH A O   
4713 O O   . HOH G .   ? 0.45210 0.58730 0.39580 -0.04450 0.05510  0.12610  594 HOH A O   
4714 O O   . HOH G .   ? 0.13420 0.42890 0.31550 -0.00090 -0.00770 0.13820  595 HOH A O   
4715 O O   . HOH G .   ? 0.51220 0.47920 0.36480 -0.04520 -0.07580 -0.03870 596 HOH A O   
4716 O O   . HOH G .   ? 0.32060 0.57820 0.45390 -0.00440 -0.10930 0.04790  597 HOH A O   
4717 O O   . HOH G .   ? 0.48110 0.39050 0.33750 -0.03570 0.14200  0.00930  598 HOH A O   
4718 O O   . HOH G .   ? 0.31090 0.51580 0.34940 -0.04160 0.03860  0.13520  599 HOH A O   
4719 O O   . HOH G .   ? 0.29420 0.41730 0.47770 -0.02180 0.00110  0.00870  600 HOH A O   
4720 O O   . HOH G .   ? 0.36420 0.51570 0.59200 -0.15670 -0.07130 0.01760  601 HOH A O   
4721 O O   . HOH G .   ? 0.64360 0.63690 0.52890 -0.04480 -0.02730 0.07210  602 HOH A O   
4722 O O   . HOH G .   ? 0.68960 0.56530 0.37980 0.06440  -0.06140 -0.00190 603 HOH A O   
4723 O O   . HOH G .   ? 0.43840 0.61740 0.42780 -0.05710 -0.08290 -0.06090 604 HOH A O   
4724 O O   . HOH G .   ? 0.53190 0.51770 0.62500 0.06060  0.01850  -0.02360 605 HOH A O   
4725 O O   . HOH G .   ? 0.62300 0.66070 0.72370 -0.05540 0.03750  0.00510  606 HOH A O   
4726 O O   . HOH G .   ? 0.58310 0.50700 0.56560 0.07690  0.06060  0.07820  607 HOH A O   
4727 O O   . HOH G .   ? 0.43810 0.50320 0.59890 -0.06830 0.06690  -0.07290 608 HOH A O   
4728 O O   . HOH G .   ? 0.68900 0.77670 0.83900 0.00550  -0.00680 0.14790  609 HOH A O   
4729 O O   . HOH G .   ? 0.50220 0.66030 0.51590 0.12600  -0.10030 -0.02740 610 HOH A O   
4730 O O   . HOH G .   ? 0.21840 0.62650 0.19050 0.06090  0.00440  -0.00920 611 HOH A O   
4731 O O   . HOH G .   ? 0.29970 0.51630 0.28860 0.09400  0.07150  -0.06700 612 HOH A O   
4732 O O   A HOH G .   ? 0.52000 0.55470 0.57590 -0.03840 -0.04720 0.14040  613 HOH A O   
4733 O O   . HOH G .   ? 0.51760 0.44870 0.58320 -0.17180 0.09140  -0.15230 614 HOH A O   
4734 O O   . HOH G .   ? 0.56600 0.46810 0.53040 0.05690  0.01990  0.06510  615 HOH A O   
4735 O O   . HOH G .   ? 0.58670 0.50440 0.39310 0.18840  0.16470  0.17050  616 HOH A O   
4736 O O   . HOH G .   ? 0.63860 0.72090 0.73910 -0.09430 0.00890  0.05640  617 HOH A O   
4737 O O   . HOH G .   ? 0.55430 0.58530 0.54690 -0.10070 0.15880  -0.10910 618 HOH A O   
4738 O O   . HOH G .   ? 0.52760 0.43680 0.61720 0.08290  -0.01760 -0.09080 619 HOH A O   
4739 O O   . HOH G .   ? 0.67580 0.63290 0.44320 0.07180  0.12850  -0.00120 620 HOH A O   
4740 O O   . HOH G .   ? 0.65070 0.48800 0.51420 -0.00990 -0.12720 0.03540  621 HOH A O   
4741 O O   . HOH G .   ? 0.38630 0.47240 0.45100 0.00410  0.07180  -0.02270 622 HOH A O   
4742 O O   . HOH G .   ? 0.72660 0.61700 0.64970 -0.10610 0.06420  -0.02010 623 HOH A O   
4743 O O   . HOH G .   ? 0.46110 0.53180 0.53000 -0.15230 0.14230  -0.09600 624 HOH A O   
4744 O O   . HOH G .   ? 0.51910 0.59280 0.58730 0.17570  0.17450  0.05060  625 HOH A O   
4745 O O   A HOH G .   ? 0.53550 0.51340 0.19660 0.00740  0.06750  0.07970  626 HOH A O   
4746 O O   . HOH G .   ? 0.28460 0.45460 0.23830 0.03920  -0.02230 0.01550  627 HOH A O   
4747 O O   . HOH G .   ? 0.61490 0.46160 0.53040 -0.12760 0.05320  0.05240  628 HOH A O   
4748 O O   . HOH G .   ? 0.63180 0.48980 0.36450 0.01640  -0.06600 -0.20190 629 HOH A O   
4749 O O   . HOH G .   ? 0.82760 0.70240 0.81810 0.19180  0.00700  0.03920  630 HOH A O   
4750 O O   . HOH G .   ? 0.28260 0.51710 0.59580 0.06520  0.01030  0.00650  631 HOH A O   
4751 O O   . HOH G .   ? 0.28530 0.52080 0.29720 -0.12030 -0.08250 0.10090  632 HOH A O   
4752 O O   B HOH G .   ? 0.39830 0.54260 0.37690 0.01020  -0.06350 0.08830  633 HOH A O   
4753 O O   . HOH G .   ? 0.41990 0.60390 0.58600 0.15560  0.22640  0.07840  634 HOH A O   
4754 O O   . HOH G .   ? 0.70270 0.63590 0.46940 0.05750  0.04600  0.03360  635 HOH A O   
4755 O O   . HOH G .   ? 0.18390 0.52060 0.16170 -0.09890 0.01200  -0.02360 636 HOH A O   
4756 O O   . HOH G .   ? 0.71770 0.61690 0.58170 0.00110  -0.09270 -0.05250 637 HOH A O   
4757 O O   . HOH G .   ? 0.46880 0.55580 0.40320 0.12860  -0.16440 -0.14620 638 HOH A O   
4758 O O   . HOH G .   ? 0.47400 0.44720 0.25160 -0.05390 -0.05080 0.00300  639 HOH A O   
4759 O O   . HOH G .   ? 0.36520 0.67040 0.44640 0.05290  0.09380  0.18530  640 HOH A O   
4760 O O   . HOH G .   ? 0.69130 0.59260 0.74610 -0.03890 -0.02410 -0.02730 641 HOH A O   
4761 O O   . HOH G .   ? 0.21360 0.56760 0.23380 -0.03890 0.01820  -0.02610 642 HOH A O   
4762 O O   . HOH G .   ? 0.66480 0.45970 0.54400 0.00180  0.06000  -0.10830 643 HOH A O   
4763 O O   . HOH G .   ? 0.54450 0.38600 0.43470 -0.12360 -0.12190 -0.01530 644 HOH A O   
4764 O O   . HOH G .   ? 0.78340 0.68180 0.67690 -0.01280 -0.05120 0.03540  645 HOH A O   
4765 O O   . HOH G .   ? 0.37430 0.35480 0.21640 -0.01670 -0.02790 0.04750  646 HOH A O   
4766 O O   . HOH G .   ? 0.52680 0.54990 0.45300 -0.10200 -0.11130 -0.09830 647 HOH A O   
4767 O O   . HOH G .   ? 0.37810 0.40000 0.28020 0.09090  0.00540  0.07430  648 HOH A O   
4768 O O   . HOH G .   ? 0.41660 0.68920 0.67000 0.02650  -0.05080 -0.02420 649 HOH A O   
4769 O O   . HOH G .   ? 0.54540 0.53390 0.56770 -0.01740 -0.01210 0.05680  650 HOH A O   
4770 O O   . HOH G .   ? 0.32200 0.33710 0.22880 -0.04530 -0.00590 0.01100  651 HOH A O   
4771 O O   . HOH G .   ? 0.84810 0.80150 0.86480 0.01560  -0.00870 0.02570  652 HOH A O   
4772 O O   . HOH G .   ? 0.65270 0.65180 0.66440 -0.08700 0.06410  -0.00910 653 HOH A O   
4773 O O   . HOH G .   ? 0.45750 0.51300 0.45420 0.13740  -0.02010 -0.05460 654 HOH A O   
4774 O O   . HOH G .   ? 0.51270 0.43430 0.52890 -0.07910 -0.10330 -0.03470 655 HOH A O   
4775 O O   . HOH G .   ? 0.54340 0.48140 0.27860 0.05150  0.01040  0.02880  656 HOH A O   
4776 O O   . HOH G .   ? 0.15390 0.37260 0.19860 -0.01580 0.00310  -0.08770 657 HOH A O   
4777 O O   . HOH G .   ? 0.39120 0.53730 0.43390 -0.08590 0.03120  -0.12940 658 HOH A O   
4778 O O   . HOH G .   ? 0.62000 0.55490 0.49700 0.02470  -0.00060 0.08950  659 HOH A O   
4779 O O   . HOH G .   ? 0.38170 0.44900 0.56800 -0.00860 0.06590  0.06980  660 HOH A O   
4780 O O   . HOH G .   ? 0.55710 0.66930 0.51480 0.11100  0.10430  -0.04450 661 HOH A O   
4781 O O   . HOH G .   ? 0.27010 0.55610 0.30200 0.06130  -0.02850 -0.10280 662 HOH A O   
4782 O O   . HOH G .   ? 0.48380 0.46570 0.49280 0.07830  0.01570  0.03470  663 HOH A O   
4783 O O   . HOH G .   ? 0.41920 0.63100 0.42930 0.08360  0.08880  0.20260  664 HOH A O   
4784 O O   . HOH G .   ? 0.51530 0.40790 0.42980 0.01370  0.10510  -0.11860 665 HOH A O   
4785 O O   . HOH G .   ? 0.46090 0.44830 0.42400 0.08050  -0.12610 -0.08520 666 HOH A O   
4786 O O   . HOH G .   ? 0.62740 0.65040 0.68070 -0.09870 0.00540  0.01810  667 HOH A O   
4787 O O   . HOH G .   ? 0.31150 0.40320 0.51750 0.00120  -0.00750 0.07000  668 HOH A O   
4788 O O   . HOH G .   ? 0.63640 0.51090 0.66090 0.10910  -0.11620 0.06270  669 HOH A O   
4789 O O   . HOH G .   ? 0.63430 0.63360 0.57360 0.03670  -0.06540 0.02740  670 HOH A O   
4790 O O   . HOH G .   ? 0.52250 0.55250 0.39780 0.07900  0.12730  0.03420  671 HOH A O   
4791 O O   . HOH G .   ? 0.51510 0.65360 0.68360 -0.03510 -0.03100 0.03540  672 HOH A O   
4792 O O   . HOH G .   ? 1.01950 1.10010 1.05110 0.02690  0.04880  -0.08330 673 HOH A O   
4793 O O   . HOH G .   ? 0.32310 0.55850 0.40230 -0.10850 -0.11630 0.04900  674 HOH A O   
4794 O O   . HOH G .   ? 0.71660 0.80390 0.68140 -0.01050 -0.02690 0.08600  675 HOH A O   
4795 O O   A HOH G .   ? 0.40570 0.49590 0.33610 0.07730  0.10560  0.09670  676 HOH A O   
4796 O O   . HOH G .   ? 0.33610 0.51250 0.30470 0.01700  -0.00300 0.01540  677 HOH A O   
4797 O O   . HOH G .   ? 0.39550 0.48760 0.58380 0.07530  0.01730  -0.10590 678 HOH A O   
4798 O O   . HOH G .   ? 0.43600 0.40750 0.38780 -0.06890 0.03070  -0.08190 679 HOH A O   
4799 O O   . HOH G .   ? 0.49530 0.45410 0.54030 -0.05610 0.01350  -0.11410 680 HOH A O   
4800 O O   . HOH G .   ? 0.84140 0.68670 0.74030 0.03240  -0.01370 0.03660  681 HOH A O   
4801 O O   . HOH G .   ? 0.39710 0.49200 0.55020 0.00010  0.07850  0.02020  682 HOH A O   
4802 O O   . HOH G .   ? 0.45330 0.56390 0.59240 0.05520  0.14300  0.13300  683 HOH A O   
4803 O O   . HOH G .   ? 1.16940 1.07560 1.06810 0.02630  0.00160  0.04650  684 HOH A O   
4804 O O   . HOH G .   ? 0.47120 0.34680 0.56610 -0.04760 0.02950  0.08500  685 HOH A O   
4805 O O   . HOH G .   ? 0.33530 0.58300 0.31680 -0.03700 -0.04200 0.05160  686 HOH A O   
4806 O O   D HOH G .   ? 0.52330 0.56410 0.64450 0.02620  -0.04910 0.06480  687 HOH A O   
4807 O O   . HOH G .   ? 0.55950 0.37930 0.34130 -0.12070 -0.01220 0.03700  688 HOH A O   
4808 O O   . HOH G .   ? 0.46750 0.56440 0.48100 0.11170  0.11000  0.14990  689 HOH A O   
4809 O O   . HOH G .   ? 0.42800 0.55430 0.51800 -0.09120 0.04770  0.01970  690 HOH A O   
4810 O O   . HOH G .   ? 0.57500 0.68910 0.47580 -0.01360 0.05630  0.12770  691 HOH A O   
# 
