data_8RL6
# 
_entry.id   8RL6 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8RL6         pdb_00008rl6 10.2210/pdb8rl6/pdb 
WWPDB D_1292135646 ?            ?                   
EMDB  EMD-19332    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-15 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8RL6 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'DNA helicase RECQL5 in complex with homo Di-Gluebody G5-006 - RECQL5 local refinement' 
_pdbx_database_related.db_id          EMD-19332 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
4 robert.gilbert@magd.ox.ac.uk Robert   Gilbert     J.C. 'principal investigator/group leader' 0000-0001-9336-5604 
5 david.sauer@cmd.ox.ac.uk     David    Sauer       B.   'principal investigator/group leader' 0000-0001-9291-4640 
6 ben.davis@rfi.ac.uk          Benjamin Davis       G.   'principal investigator/group leader' 0000-0002-5056-407X 
7 frank.vondelft@cmd.ox.ac.uk  Frank    'von Delft' ?    'principal investigator/group leader' 0000-0003-0378-0017 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yi, G.'          1 0009-0004-6509-4893 
'Ye, M.'          2 0000-0001-6324-4238 
'Mamalis, D.'     3 0000-0002-4396-7495 
'Sauer, D.B.'     4 0000-0001-9291-4640 
'von Delft, F.'   5 0000-0003-0378-0017 
'Davis, B.G.'     6 0000-0002-5056-407X 
'Gilbert, R.J.C.' 7 0000-0001-9336-5604 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Di-Gluebodies: Rigid modular nanobody protein assemblies enabling simultaneous determination of high-resolution cryo-EM structures' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yi, G.'          1  0009-0004-6509-4893 
primary 'Mamalis, D.'     2  0000-0002-4396-7495 
primary 'Ye, M.'          3  0000-0001-6324-4238 
primary 'Carrique, L.'    4  0000-0001-5332-8593 
primary 'Fairhead, M.'    5  0000-0001-5361-3933 
primary 'Li, H.'          6  0000-0002-5482-9936 
primary 'Duerr, K.'       7  0000-0002-3245-4088 
primary 'Zhang, P.'       8  0000-0003-1803-691X 
primary 'Sauer, D.B.'     9  0000-0001-9291-4640 
primary 'von Delft, F.'   10 0000-0003-0378-0017 
primary 'Davis, B.G.'     11 0000-0002-5056-407X 
primary 'Gilbert, R.J.C.' 12 0000-0001-9336-5604 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'ATP-dependent DNA helicase Q5' 49203.820 1 3.6.4.12 ? ? ? 
2 non-polymer syn 'ZINC ION'                      65.409    1 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'DNA helicase,RecQ-like type 5,RecQ5,RecQ protein-like 5' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;PERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQVDHLL
TLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRP
DYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALG
QEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFV
AHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGC
RHAAIAKYFGDALPACAKGCDHCQNPTAVRRRLEALERSSSW
;
_entity_poly.pdbx_seq_one_letter_code_can   
;PERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQVDHLL
TLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRP
DYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALG
QEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFV
AHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGC
RHAAIAKYFGDALPACAKGCDHCQNPTAVRRRLEALERSSSW
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'ZINC ION' 
_pdbx_entity_nonpoly.comp_id     ZN 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PRO n 
1 2   GLU n 
1 3   ARG n 
1 4   ARG n 
1 5   VAL n 
1 6   ARG n 
1 7   SER n 
1 8   THR n 
1 9   LEU n 
1 10  LYS n 
1 11  LYS n 
1 12  VAL n 
1 13  PHE n 
1 14  GLY n 
1 15  PHE n 
1 16  ASP n 
1 17  SER n 
1 18  PHE n 
1 19  LYS n 
1 20  THR n 
1 21  PRO n 
1 22  LEU n 
1 23  GLN n 
1 24  GLU n 
1 25  SER n 
1 26  ALA n 
1 27  THR n 
1 28  MET n 
1 29  ALA n 
1 30  VAL n 
1 31  VAL n 
1 32  LYS n 
1 33  GLY n 
1 34  ASN n 
1 35  LYS n 
1 36  ASP n 
1 37  VAL n 
1 38  PHE n 
1 39  VAL n 
1 40  CYS n 
1 41  MET n 
1 42  PRO n 
1 43  THR n 
1 44  GLY n 
1 45  ALA n 
1 46  GLY n 
1 47  LYS n 
1 48  SER n 
1 49  LEU n 
1 50  CYS n 
1 51  TYR n 
1 52  GLN n 
1 53  LEU n 
1 54  PRO n 
1 55  ALA n 
1 56  LEU n 
1 57  LEU n 
1 58  ALA n 
1 59  LYS n 
1 60  GLY n 
1 61  ILE n 
1 62  THR n 
1 63  ILE n 
1 64  VAL n 
1 65  VAL n 
1 66  SER n 
1 67  PRO n 
1 68  LEU n 
1 69  ILE n 
1 70  ALA n 
1 71  LEU n 
1 72  ILE n 
1 73  GLN n 
1 74  ASP n 
1 75  GLN n 
1 76  VAL n 
1 77  ASP n 
1 78  HIS n 
1 79  LEU n 
1 80  LEU n 
1 81  THR n 
1 82  LEU n 
1 83  LYS n 
1 84  VAL n 
1 85  ARG n 
1 86  VAL n 
1 87  SER n 
1 88  SER n 
1 89  LEU n 
1 90  ASN n 
1 91  SER n 
1 92  LYS n 
1 93  LEU n 
1 94  SER n 
1 95  ALA n 
1 96  GLN n 
1 97  GLU n 
1 98  ARG n 
1 99  LYS n 
1 100 GLU n 
1 101 LEU n 
1 102 LEU n 
1 103 ALA n 
1 104 ASP n 
1 105 LEU n 
1 106 GLU n 
1 107 ARG n 
1 108 GLU n 
1 109 LYS n 
1 110 PRO n 
1 111 GLN n 
1 112 THR n 
1 113 LYS n 
1 114 ILE n 
1 115 LEU n 
1 116 TYR n 
1 117 ILE n 
1 118 THR n 
1 119 PRO n 
1 120 GLU n 
1 121 MET n 
1 122 ALA n 
1 123 ALA n 
1 124 SER n 
1 125 SER n 
1 126 SER n 
1 127 PHE n 
1 128 GLN n 
1 129 PRO n 
1 130 THR n 
1 131 LEU n 
1 132 ASN n 
1 133 SER n 
1 134 LEU n 
1 135 VAL n 
1 136 SER n 
1 137 ARG n 
1 138 HIS n 
1 139 LEU n 
1 140 LEU n 
1 141 SER n 
1 142 TYR n 
1 143 LEU n 
1 144 VAL n 
1 145 VAL n 
1 146 ASP n 
1 147 GLU n 
1 148 ALA n 
1 149 HIS n 
1 150 CYS n 
1 151 VAL n 
1 152 SER n 
1 153 GLN n 
1 154 TRP n 
1 155 GLY n 
1 156 HIS n 
1 157 ASP n 
1 158 PHE n 
1 159 ARG n 
1 160 PRO n 
1 161 ASP n 
1 162 TYR n 
1 163 LEU n 
1 164 ARG n 
1 165 LEU n 
1 166 GLY n 
1 167 ALA n 
1 168 LEU n 
1 169 ARG n 
1 170 SER n 
1 171 ARG n 
1 172 LEU n 
1 173 GLY n 
1 174 HIS n 
1 175 ALA n 
1 176 PRO n 
1 177 CYS n 
1 178 VAL n 
1 179 ALA n 
1 180 LEU n 
1 181 THR n 
1 182 ALA n 
1 183 THR n 
1 184 ALA n 
1 185 THR n 
1 186 PRO n 
1 187 GLN n 
1 188 VAL n 
1 189 GLN n 
1 190 GLU n 
1 191 ASP n 
1 192 VAL n 
1 193 PHE n 
1 194 ALA n 
1 195 ALA n 
1 196 LEU n 
1 197 HIS n 
1 198 LEU n 
1 199 LYS n 
1 200 LYS n 
1 201 PRO n 
1 202 VAL n 
1 203 ALA n 
1 204 ILE n 
1 205 PHE n 
1 206 LYS n 
1 207 THR n 
1 208 PRO n 
1 209 CYS n 
1 210 PHE n 
1 211 ARG n 
1 212 ALA n 
1 213 ASN n 
1 214 LEU n 
1 215 PHE n 
1 216 TYR n 
1 217 ASP n 
1 218 VAL n 
1 219 GLN n 
1 220 PHE n 
1 221 LYS n 
1 222 GLU n 
1 223 LEU n 
1 224 ILE n 
1 225 SER n 
1 226 ASP n 
1 227 PRO n 
1 228 TYR n 
1 229 GLY n 
1 230 ASN n 
1 231 LEU n 
1 232 LYS n 
1 233 ASP n 
1 234 PHE n 
1 235 CYS n 
1 236 LEU n 
1 237 LYS n 
1 238 ALA n 
1 239 LEU n 
1 240 GLY n 
1 241 GLN n 
1 242 GLU n 
1 243 ALA n 
1 244 ASP n 
1 245 LYS n 
1 246 GLY n 
1 247 LEU n 
1 248 SER n 
1 249 GLY n 
1 250 CYS n 
1 251 GLY n 
1 252 ILE n 
1 253 VAL n 
1 254 TYR n 
1 255 CYS n 
1 256 ARG n 
1 257 THR n 
1 258 ARG n 
1 259 GLU n 
1 260 ALA n 
1 261 CYS n 
1 262 GLU n 
1 263 GLN n 
1 264 LEU n 
1 265 ALA n 
1 266 ILE n 
1 267 GLU n 
1 268 LEU n 
1 269 SER n 
1 270 CYS n 
1 271 ARG n 
1 272 GLY n 
1 273 VAL n 
1 274 ASN n 
1 275 ALA n 
1 276 LYS n 
1 277 ALA n 
1 278 TYR n 
1 279 HIS n 
1 280 ALA n 
1 281 GLY n 
1 282 LEU n 
1 283 LYS n 
1 284 ALA n 
1 285 SER n 
1 286 GLU n 
1 287 ARG n 
1 288 THR n 
1 289 LEU n 
1 290 VAL n 
1 291 GLN n 
1 292 ASN n 
1 293 ASP n 
1 294 TRP n 
1 295 MET n 
1 296 GLU n 
1 297 GLU n 
1 298 LYS n 
1 299 VAL n 
1 300 PRO n 
1 301 VAL n 
1 302 ILE n 
1 303 VAL n 
1 304 ALA n 
1 305 THR n 
1 306 ILE n 
1 307 SER n 
1 308 PHE n 
1 309 GLY n 
1 310 MET n 
1 311 GLY n 
1 312 VAL n 
1 313 ASP n 
1 314 LYS n 
1 315 ALA n 
1 316 ASN n 
1 317 VAL n 
1 318 ARG n 
1 319 PHE n 
1 320 VAL n 
1 321 ALA n 
1 322 HIS n 
1 323 TRP n 
1 324 ASN n 
1 325 ILE n 
1 326 ALA n 
1 327 LYS n 
1 328 SER n 
1 329 MET n 
1 330 ALA n 
1 331 GLY n 
1 332 TYR n 
1 333 TYR n 
1 334 GLN n 
1 335 GLU n 
1 336 SER n 
1 337 GLY n 
1 338 ARG n 
1 339 ALA n 
1 340 GLY n 
1 341 ARG n 
1 342 ASP n 
1 343 GLY n 
1 344 LYS n 
1 345 PRO n 
1 346 SER n 
1 347 TRP n 
1 348 CYS n 
1 349 ARG n 
1 350 LEU n 
1 351 TYR n 
1 352 TYR n 
1 353 SER n 
1 354 ARG n 
1 355 ASN n 
1 356 ASP n 
1 357 ARG n 
1 358 ASP n 
1 359 GLN n 
1 360 VAL n 
1 361 SER n 
1 362 PHE n 
1 363 LEU n 
1 364 ILE n 
1 365 ARG n 
1 366 LYS n 
1 367 GLU n 
1 368 VAL n 
1 369 ALA n 
1 370 LYS n 
1 371 LEU n 
1 372 GLN n 
1 373 GLU n 
1 374 LYS n 
1 375 ARG n 
1 376 GLY n 
1 377 ASN n 
1 378 LYS n 
1 379 ALA n 
1 380 SER n 
1 381 ASP n 
1 382 LYS n 
1 383 ALA n 
1 384 THR n 
1 385 ILE n 
1 386 MET n 
1 387 ALA n 
1 388 PHE n 
1 389 ASP n 
1 390 ALA n 
1 391 LEU n 
1 392 VAL n 
1 393 THR n 
1 394 PHE n 
1 395 CYS n 
1 396 GLU n 
1 397 GLU n 
1 398 LEU n 
1 399 GLY n 
1 400 CYS n 
1 401 ARG n 
1 402 HIS n 
1 403 ALA n 
1 404 ALA n 
1 405 ILE n 
1 406 ALA n 
1 407 LYS n 
1 408 TYR n 
1 409 PHE n 
1 410 GLY n 
1 411 ASP n 
1 412 ALA n 
1 413 LEU n 
1 414 PRO n 
1 415 ALA n 
1 416 CYS n 
1 417 ALA n 
1 418 LYS n 
1 419 GLY n 
1 420 CYS n 
1 421 ASP n 
1 422 HIS n 
1 423 CYS n 
1 424 GLN n 
1 425 ASN n 
1 426 PRO n 
1 427 THR n 
1 428 ALA n 
1 429 VAL n 
1 430 ARG n 
1 431 ARG n 
1 432 ARG n 
1 433 LEU n 
1 434 GLU n 
1 435 ALA n 
1 436 LEU n 
1 437 GLU n 
1 438 ARG n 
1 439 SER n 
1 440 SER n 
1 441 SER n 
1 442 TRP n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   442 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'RECQL5, RECQ5' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'      ? 'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PRO 1   12  12  PRO PRO A . n 
A 1 2   GLU 2   13  13  GLU GLU A . n 
A 1 3   ARG 3   14  14  ARG ARG A . n 
A 1 4   ARG 4   15  15  ARG ARG A . n 
A 1 5   VAL 5   16  16  VAL VAL A . n 
A 1 6   ARG 6   17  17  ARG ARG A . n 
A 1 7   SER 7   18  18  SER SER A . n 
A 1 8   THR 8   19  19  THR THR A . n 
A 1 9   LEU 9   20  20  LEU LEU A . n 
A 1 10  LYS 10  21  21  LYS LYS A . n 
A 1 11  LYS 11  22  22  LYS LYS A . n 
A 1 12  VAL 12  23  23  VAL VAL A . n 
A 1 13  PHE 13  24  24  PHE PHE A . n 
A 1 14  GLY 14  25  25  GLY GLY A . n 
A 1 15  PHE 15  26  26  PHE PHE A . n 
A 1 16  ASP 16  27  27  ASP ASP A . n 
A 1 17  SER 17  28  28  SER SER A . n 
A 1 18  PHE 18  29  29  PHE PHE A . n 
A 1 19  LYS 19  30  30  LYS LYS A . n 
A 1 20  THR 20  31  31  THR THR A . n 
A 1 21  PRO 21  32  32  PRO PRO A . n 
A 1 22  LEU 22  33  33  LEU LEU A . n 
A 1 23  GLN 23  34  34  GLN GLN A . n 
A 1 24  GLU 24  35  35  GLU GLU A . n 
A 1 25  SER 25  36  36  SER SER A . n 
A 1 26  ALA 26  37  37  ALA ALA A . n 
A 1 27  THR 27  38  38  THR THR A . n 
A 1 28  MET 28  39  39  MET MET A . n 
A 1 29  ALA 29  40  40  ALA ALA A . n 
A 1 30  VAL 30  41  41  VAL VAL A . n 
A 1 31  VAL 31  42  42  VAL VAL A . n 
A 1 32  LYS 32  43  43  LYS LYS A . n 
A 1 33  GLY 33  44  44  GLY GLY A . n 
A 1 34  ASN 34  45  45  ASN ASN A . n 
A 1 35  LYS 35  46  46  LYS LYS A . n 
A 1 36  ASP 36  47  47  ASP ASP A . n 
A 1 37  VAL 37  48  48  VAL VAL A . n 
A 1 38  PHE 38  49  49  PHE PHE A . n 
A 1 39  VAL 39  50  50  VAL VAL A . n 
A 1 40  CYS 40  51  51  CYS CYS A . n 
A 1 41  MET 41  52  52  MET MET A . n 
A 1 42  PRO 42  53  53  PRO PRO A . n 
A 1 43  THR 43  54  54  THR THR A . n 
A 1 44  GLY 44  55  55  GLY GLY A . n 
A 1 45  ALA 45  56  56  ALA ALA A . n 
A 1 46  GLY 46  57  57  GLY GLY A . n 
A 1 47  LYS 47  58  58  LYS LYS A . n 
A 1 48  SER 48  59  59  SER SER A . n 
A 1 49  LEU 49  60  60  LEU LEU A . n 
A 1 50  CYS 50  61  61  CYS CYS A . n 
A 1 51  TYR 51  62  62  TYR TYR A . n 
A 1 52  GLN 52  63  63  GLN GLN A . n 
A 1 53  LEU 53  64  64  LEU LEU A . n 
A 1 54  PRO 54  65  65  PRO PRO A . n 
A 1 55  ALA 55  66  66  ALA ALA A . n 
A 1 56  LEU 56  67  67  LEU LEU A . n 
A 1 57  LEU 57  68  68  LEU LEU A . n 
A 1 58  ALA 58  69  69  ALA ALA A . n 
A 1 59  LYS 59  70  70  LYS LYS A . n 
A 1 60  GLY 60  71  71  GLY GLY A . n 
A 1 61  ILE 61  72  72  ILE ILE A . n 
A 1 62  THR 62  73  73  THR THR A . n 
A 1 63  ILE 63  74  74  ILE ILE A . n 
A 1 64  VAL 64  75  75  VAL VAL A . n 
A 1 65  VAL 65  76  76  VAL VAL A . n 
A 1 66  SER 66  77  77  SER SER A . n 
A 1 67  PRO 67  78  78  PRO PRO A . n 
A 1 68  LEU 68  79  79  LEU LEU A . n 
A 1 69  ILE 69  80  80  ILE ILE A . n 
A 1 70  ALA 70  81  81  ALA ALA A . n 
A 1 71  LEU 71  82  82  LEU LEU A . n 
A 1 72  ILE 72  83  83  ILE ILE A . n 
A 1 73  GLN 73  84  84  GLN GLN A . n 
A 1 74  ASP 74  85  85  ASP ASP A . n 
A 1 75  GLN 75  86  86  GLN GLN A . n 
A 1 76  VAL 76  87  87  VAL VAL A . n 
A 1 77  ASP 77  88  88  ASP ASP A . n 
A 1 78  HIS 78  89  89  HIS HIS A . n 
A 1 79  LEU 79  90  90  LEU LEU A . n 
A 1 80  LEU 80  91  91  LEU LEU A . n 
A 1 81  THR 81  92  92  THR THR A . n 
A 1 82  LEU 82  93  93  LEU LEU A . n 
A 1 83  LYS 83  94  94  LYS LYS A . n 
A 1 84  VAL 84  95  95  VAL VAL A . n 
A 1 85  ARG 85  96  96  ARG ARG A . n 
A 1 86  VAL 86  97  97  VAL VAL A . n 
A 1 87  SER 87  98  98  SER SER A . n 
A 1 88  SER 88  99  99  SER SER A . n 
A 1 89  LEU 89  100 100 LEU LEU A . n 
A 1 90  ASN 90  101 101 ASN ASN A . n 
A 1 91  SER 91  102 102 SER SER A . n 
A 1 92  LYS 92  103 103 LYS LYS A . n 
A 1 93  LEU 93  104 104 LEU LEU A . n 
A 1 94  SER 94  105 105 SER SER A . n 
A 1 95  ALA 95  106 106 ALA ALA A . n 
A 1 96  GLN 96  107 107 GLN GLN A . n 
A 1 97  GLU 97  108 108 GLU GLU A . n 
A 1 98  ARG 98  109 109 ARG ARG A . n 
A 1 99  LYS 99  110 110 LYS LYS A . n 
A 1 100 GLU 100 111 111 GLU GLU A . n 
A 1 101 LEU 101 112 112 LEU LEU A . n 
A 1 102 LEU 102 113 113 LEU LEU A . n 
A 1 103 ALA 103 114 114 ALA ALA A . n 
A 1 104 ASP 104 115 115 ASP ASP A . n 
A 1 105 LEU 105 116 116 LEU LEU A . n 
A 1 106 GLU 106 117 117 GLU GLU A . n 
A 1 107 ARG 107 118 118 ARG ARG A . n 
A 1 108 GLU 108 119 119 GLU GLU A . n 
A 1 109 LYS 109 120 120 LYS LYS A . n 
A 1 110 PRO 110 121 121 PRO PRO A . n 
A 1 111 GLN 111 122 122 GLN GLN A . n 
A 1 112 THR 112 123 123 THR THR A . n 
A 1 113 LYS 113 124 124 LYS LYS A . n 
A 1 114 ILE 114 125 125 ILE ILE A . n 
A 1 115 LEU 115 126 126 LEU LEU A . n 
A 1 116 TYR 116 127 127 TYR TYR A . n 
A 1 117 ILE 117 128 128 ILE ILE A . n 
A 1 118 THR 118 129 129 THR THR A . n 
A 1 119 PRO 119 130 130 PRO PRO A . n 
A 1 120 GLU 120 131 131 GLU GLU A . n 
A 1 121 MET 121 132 132 MET MET A . n 
A 1 122 ALA 122 133 133 ALA ALA A . n 
A 1 123 ALA 123 134 134 ALA ALA A . n 
A 1 124 SER 124 135 135 SER SER A . n 
A 1 125 SER 125 136 136 SER SER A . n 
A 1 126 SER 126 137 137 SER SER A . n 
A 1 127 PHE 127 138 138 PHE PHE A . n 
A 1 128 GLN 128 139 139 GLN GLN A . n 
A 1 129 PRO 129 140 140 PRO PRO A . n 
A 1 130 THR 130 141 141 THR THR A . n 
A 1 131 LEU 131 142 142 LEU LEU A . n 
A 1 132 ASN 132 143 143 ASN ASN A . n 
A 1 133 SER 133 144 144 SER SER A . n 
A 1 134 LEU 134 145 145 LEU LEU A . n 
A 1 135 VAL 135 146 146 VAL VAL A . n 
A 1 136 SER 136 147 147 SER SER A . n 
A 1 137 ARG 137 148 148 ARG ARG A . n 
A 1 138 HIS 138 149 149 HIS HIS A . n 
A 1 139 LEU 139 150 150 LEU LEU A . n 
A 1 140 LEU 140 151 151 LEU LEU A . n 
A 1 141 SER 141 152 152 SER SER A . n 
A 1 142 TYR 142 153 153 TYR TYR A . n 
A 1 143 LEU 143 154 154 LEU LEU A . n 
A 1 144 VAL 144 155 155 VAL VAL A . n 
A 1 145 VAL 145 156 156 VAL VAL A . n 
A 1 146 ASP 146 157 157 ASP ASP A . n 
A 1 147 GLU 147 158 158 GLU GLU A . n 
A 1 148 ALA 148 159 159 ALA ALA A . n 
A 1 149 HIS 149 160 160 HIS HIS A . n 
A 1 150 CYS 150 161 161 CYS CYS A . n 
A 1 151 VAL 151 162 162 VAL VAL A . n 
A 1 152 SER 152 163 163 SER SER A . n 
A 1 153 GLN 153 164 164 GLN GLN A . n 
A 1 154 TRP 154 165 165 TRP TRP A . n 
A 1 155 GLY 155 166 166 GLY GLY A . n 
A 1 156 HIS 156 167 167 HIS HIS A . n 
A 1 157 ASP 157 168 168 ASP ASP A . n 
A 1 158 PHE 158 169 169 PHE PHE A . n 
A 1 159 ARG 159 170 170 ARG ARG A . n 
A 1 160 PRO 160 171 171 PRO PRO A . n 
A 1 161 ASP 161 172 172 ASP ASP A . n 
A 1 162 TYR 162 173 173 TYR TYR A . n 
A 1 163 LEU 163 174 174 LEU LEU A . n 
A 1 164 ARG 164 175 175 ARG ARG A . n 
A 1 165 LEU 165 176 176 LEU LEU A . n 
A 1 166 GLY 166 177 177 GLY GLY A . n 
A 1 167 ALA 167 178 178 ALA ALA A . n 
A 1 168 LEU 168 179 179 LEU LEU A . n 
A 1 169 ARG 169 180 180 ARG ARG A . n 
A 1 170 SER 170 181 181 SER SER A . n 
A 1 171 ARG 171 182 182 ARG ARG A . n 
A 1 172 LEU 172 183 183 LEU LEU A . n 
A 1 173 GLY 173 184 184 GLY GLY A . n 
A 1 174 HIS 174 185 185 HIS HIS A . n 
A 1 175 ALA 175 186 186 ALA ALA A . n 
A 1 176 PRO 176 187 187 PRO PRO A . n 
A 1 177 CYS 177 188 188 CYS CYS A . n 
A 1 178 VAL 178 189 189 VAL VAL A . n 
A 1 179 ALA 179 190 190 ALA ALA A . n 
A 1 180 LEU 180 191 191 LEU LEU A . n 
A 1 181 THR 181 192 192 THR THR A . n 
A 1 182 ALA 182 193 193 ALA ALA A . n 
A 1 183 THR 183 194 194 THR THR A . n 
A 1 184 ALA 184 195 195 ALA ALA A . n 
A 1 185 THR 185 196 196 THR THR A . n 
A 1 186 PRO 186 197 197 PRO PRO A . n 
A 1 187 GLN 187 198 198 GLN GLN A . n 
A 1 188 VAL 188 199 199 VAL VAL A . n 
A 1 189 GLN 189 200 200 GLN GLN A . n 
A 1 190 GLU 190 201 201 GLU GLU A . n 
A 1 191 ASP 191 202 202 ASP ASP A . n 
A 1 192 VAL 192 203 203 VAL VAL A . n 
A 1 193 PHE 193 204 204 PHE PHE A . n 
A 1 194 ALA 194 205 205 ALA ALA A . n 
A 1 195 ALA 195 206 206 ALA ALA A . n 
A 1 196 LEU 196 207 207 LEU LEU A . n 
A 1 197 HIS 197 208 208 HIS HIS A . n 
A 1 198 LEU 198 209 209 LEU LEU A . n 
A 1 199 LYS 199 210 210 LYS LYS A . n 
A 1 200 LYS 200 211 211 LYS LYS A . n 
A 1 201 PRO 201 212 212 PRO PRO A . n 
A 1 202 VAL 202 213 213 VAL VAL A . n 
A 1 203 ALA 203 214 214 ALA ALA A . n 
A 1 204 ILE 204 215 215 ILE ILE A . n 
A 1 205 PHE 205 216 216 PHE PHE A . n 
A 1 206 LYS 206 217 217 LYS LYS A . n 
A 1 207 THR 207 218 218 THR THR A . n 
A 1 208 PRO 208 219 219 PRO PRO A . n 
A 1 209 CYS 209 220 220 CYS CYS A . n 
A 1 210 PHE 210 221 221 PHE PHE A . n 
A 1 211 ARG 211 222 222 ARG ARG A . n 
A 1 212 ALA 212 223 223 ALA ALA A . n 
A 1 213 ASN 213 224 224 ASN ASN A . n 
A 1 214 LEU 214 225 225 LEU LEU A . n 
A 1 215 PHE 215 226 226 PHE PHE A . n 
A 1 216 TYR 216 227 227 TYR TYR A . n 
A 1 217 ASP 217 228 228 ASP ASP A . n 
A 1 218 VAL 218 229 229 VAL VAL A . n 
A 1 219 GLN 219 230 230 GLN GLN A . n 
A 1 220 PHE 220 231 231 PHE PHE A . n 
A 1 221 LYS 221 232 232 LYS LYS A . n 
A 1 222 GLU 222 233 233 GLU GLU A . n 
A 1 223 LEU 223 234 234 LEU LEU A . n 
A 1 224 ILE 224 235 235 ILE ILE A . n 
A 1 225 SER 225 236 236 SER SER A . n 
A 1 226 ASP 226 237 237 ASP ASP A . n 
A 1 227 PRO 227 238 238 PRO PRO A . n 
A 1 228 TYR 228 239 239 TYR TYR A . n 
A 1 229 GLY 229 240 240 GLY GLY A . n 
A 1 230 ASN 230 241 241 ASN ASN A . n 
A 1 231 LEU 231 242 242 LEU LEU A . n 
A 1 232 LYS 232 243 243 LYS LYS A . n 
A 1 233 ASP 233 244 244 ASP ASP A . n 
A 1 234 PHE 234 245 245 PHE PHE A . n 
A 1 235 CYS 235 246 246 CYS CYS A . n 
A 1 236 LEU 236 247 247 LEU LEU A . n 
A 1 237 LYS 237 248 248 LYS LYS A . n 
A 1 238 ALA 238 249 249 ALA ALA A . n 
A 1 239 LEU 239 250 250 LEU LEU A . n 
A 1 240 GLY 240 251 251 GLY GLY A . n 
A 1 241 GLN 241 252 252 GLN GLN A . n 
A 1 242 GLU 242 253 253 GLU GLU A . n 
A 1 243 ALA 243 254 254 ALA ALA A . n 
A 1 244 ASP 244 255 255 ASP ASP A . n 
A 1 245 LYS 245 256 256 LYS LYS A . n 
A 1 246 GLY 246 257 257 GLY GLY A . n 
A 1 247 LEU 247 258 258 LEU LEU A . n 
A 1 248 SER 248 259 259 SER SER A . n 
A 1 249 GLY 249 260 260 GLY GLY A . n 
A 1 250 CYS 250 261 261 CYS CYS A . n 
A 1 251 GLY 251 262 262 GLY GLY A . n 
A 1 252 ILE 252 263 263 ILE ILE A . n 
A 1 253 VAL 253 264 264 VAL VAL A . n 
A 1 254 TYR 254 265 265 TYR TYR A . n 
A 1 255 CYS 255 266 266 CYS CYS A . n 
A 1 256 ARG 256 267 267 ARG ARG A . n 
A 1 257 THR 257 268 268 THR THR A . n 
A 1 258 ARG 258 269 269 ARG ARG A . n 
A 1 259 GLU 259 270 270 GLU GLU A . n 
A 1 260 ALA 260 271 271 ALA ALA A . n 
A 1 261 CYS 261 272 272 CYS CYS A . n 
A 1 262 GLU 262 273 273 GLU GLU A . n 
A 1 263 GLN 263 274 274 GLN GLN A . n 
A 1 264 LEU 264 275 275 LEU LEU A . n 
A 1 265 ALA 265 276 276 ALA ALA A . n 
A 1 266 ILE 266 277 277 ILE ILE A . n 
A 1 267 GLU 267 278 278 GLU GLU A . n 
A 1 268 LEU 268 279 279 LEU LEU A . n 
A 1 269 SER 269 280 280 SER SER A . n 
A 1 270 CYS 270 281 281 CYS CYS A . n 
A 1 271 ARG 271 282 282 ARG ARG A . n 
A 1 272 GLY 272 283 283 GLY GLY A . n 
A 1 273 VAL 273 284 284 VAL VAL A . n 
A 1 274 ASN 274 285 285 ASN ASN A . n 
A 1 275 ALA 275 286 286 ALA ALA A . n 
A 1 276 LYS 276 287 287 LYS LYS A . n 
A 1 277 ALA 277 288 288 ALA ALA A . n 
A 1 278 TYR 278 289 289 TYR TYR A . n 
A 1 279 HIS 279 290 290 HIS HIS A . n 
A 1 280 ALA 280 291 291 ALA ALA A . n 
A 1 281 GLY 281 292 292 GLY GLY A . n 
A 1 282 LEU 282 293 293 LEU LEU A . n 
A 1 283 LYS 283 294 294 LYS LYS A . n 
A 1 284 ALA 284 295 295 ALA ALA A . n 
A 1 285 SER 285 296 296 SER SER A . n 
A 1 286 GLU 286 297 297 GLU GLU A . n 
A 1 287 ARG 287 298 298 ARG ARG A . n 
A 1 288 THR 288 299 299 THR THR A . n 
A 1 289 LEU 289 300 300 LEU LEU A . n 
A 1 290 VAL 290 301 301 VAL VAL A . n 
A 1 291 GLN 291 302 302 GLN GLN A . n 
A 1 292 ASN 292 303 303 ASN ASN A . n 
A 1 293 ASP 293 304 304 ASP ASP A . n 
A 1 294 TRP 294 305 305 TRP TRP A . n 
A 1 295 MET 295 306 306 MET MET A . n 
A 1 296 GLU 296 307 307 GLU GLU A . n 
A 1 297 GLU 297 308 308 GLU GLU A . n 
A 1 298 LYS 298 309 309 LYS LYS A . n 
A 1 299 VAL 299 310 310 VAL VAL A . n 
A 1 300 PRO 300 311 311 PRO PRO A . n 
A 1 301 VAL 301 312 312 VAL VAL A . n 
A 1 302 ILE 302 313 313 ILE ILE A . n 
A 1 303 VAL 303 314 314 VAL VAL A . n 
A 1 304 ALA 304 315 315 ALA ALA A . n 
A 1 305 THR 305 316 316 THR THR A . n 
A 1 306 ILE 306 317 317 ILE ILE A . n 
A 1 307 SER 307 318 318 SER SER A . n 
A 1 308 PHE 308 319 319 PHE PHE A . n 
A 1 309 GLY 309 320 ?   ?   ?   A . n 
A 1 310 MET 310 321 ?   ?   ?   A . n 
A 1 311 GLY 311 322 ?   ?   ?   A . n 
A 1 312 VAL 312 323 ?   ?   ?   A . n 
A 1 313 ASP 313 324 324 ASP ASP A . n 
A 1 314 LYS 314 325 325 LYS LYS A . n 
A 1 315 ALA 315 326 326 ALA ALA A . n 
A 1 316 ASN 316 327 327 ASN ASN A . n 
A 1 317 VAL 317 328 328 VAL VAL A . n 
A 1 318 ARG 318 329 329 ARG ARG A . n 
A 1 319 PHE 319 330 330 PHE PHE A . n 
A 1 320 VAL 320 331 331 VAL VAL A . n 
A 1 321 ALA 321 332 332 ALA ALA A . n 
A 1 322 HIS 322 333 333 HIS HIS A . n 
A 1 323 TRP 323 334 334 TRP TRP A . n 
A 1 324 ASN 324 335 335 ASN ASN A . n 
A 1 325 ILE 325 336 336 ILE ILE A . n 
A 1 326 ALA 326 337 337 ALA ALA A . n 
A 1 327 LYS 327 338 338 LYS LYS A . n 
A 1 328 SER 328 339 339 SER SER A . n 
A 1 329 MET 329 340 340 MET MET A . n 
A 1 330 ALA 330 341 341 ALA ALA A . n 
A 1 331 GLY 331 342 342 GLY GLY A . n 
A 1 332 TYR 332 343 343 TYR TYR A . n 
A 1 333 TYR 333 344 344 TYR TYR A . n 
A 1 334 GLN 334 345 345 GLN GLN A . n 
A 1 335 GLU 335 346 346 GLU GLU A . n 
A 1 336 SER 336 347 347 SER SER A . n 
A 1 337 GLY 337 348 348 GLY GLY A . n 
A 1 338 ARG 338 349 349 ARG ARG A . n 
A 1 339 ALA 339 350 350 ALA ALA A . n 
A 1 340 GLY 340 351 351 GLY GLY A . n 
A 1 341 ARG 341 352 352 ARG ARG A . n 
A 1 342 ASP 342 353 353 ASP ASP A . n 
A 1 343 GLY 343 354 354 GLY GLY A . n 
A 1 344 LYS 344 355 355 LYS LYS A . n 
A 1 345 PRO 345 356 356 PRO PRO A . n 
A 1 346 SER 346 357 357 SER SER A . n 
A 1 347 TRP 347 358 358 TRP TRP A . n 
A 1 348 CYS 348 359 359 CYS CYS A . n 
A 1 349 ARG 349 360 360 ARG ARG A . n 
A 1 350 LEU 350 361 361 LEU LEU A . n 
A 1 351 TYR 351 362 362 TYR TYR A . n 
A 1 352 TYR 352 363 363 TYR TYR A . n 
A 1 353 SER 353 364 364 SER SER A . n 
A 1 354 ARG 354 365 365 ARG ARG A . n 
A 1 355 ASN 355 366 366 ASN ASN A . n 
A 1 356 ASP 356 367 367 ASP ASP A . n 
A 1 357 ARG 357 368 368 ARG ARG A . n 
A 1 358 ASP 358 369 369 ASP ASP A . n 
A 1 359 GLN 359 370 370 GLN GLN A . n 
A 1 360 VAL 360 371 371 VAL VAL A . n 
A 1 361 SER 361 372 372 SER SER A . n 
A 1 362 PHE 362 373 373 PHE PHE A . n 
A 1 363 LEU 363 374 374 LEU LEU A . n 
A 1 364 ILE 364 375 375 ILE ILE A . n 
A 1 365 ARG 365 376 376 ARG ARG A . n 
A 1 366 LYS 366 377 377 LYS LYS A . n 
A 1 367 GLU 367 378 378 GLU GLU A . n 
A 1 368 VAL 368 379 379 VAL VAL A . n 
A 1 369 ALA 369 380 380 ALA ALA A . n 
A 1 370 LYS 370 381 381 LYS LYS A . n 
A 1 371 LEU 371 382 382 LEU LEU A . n 
A 1 372 GLN 372 383 383 GLN GLN A . n 
A 1 373 GLU 373 384 384 GLU GLU A . n 
A 1 374 LYS 374 385 385 LYS LYS A . n 
A 1 375 ARG 375 386 386 ARG ARG A . n 
A 1 376 GLY 376 387 387 GLY GLY A . n 
A 1 377 ASN 377 388 388 ASN ASN A . n 
A 1 378 LYS 378 389 389 LYS LYS A . n 
A 1 379 ALA 379 390 390 ALA ALA A . n 
A 1 380 SER 380 391 391 SER SER A . n 
A 1 381 ASP 381 392 392 ASP ASP A . n 
A 1 382 LYS 382 393 393 LYS LYS A . n 
A 1 383 ALA 383 394 394 ALA ALA A . n 
A 1 384 THR 384 395 395 THR THR A . n 
A 1 385 ILE 385 396 396 ILE ILE A . n 
A 1 386 MET 386 397 397 MET MET A . n 
A 1 387 ALA 387 398 398 ALA ALA A . n 
A 1 388 PHE 388 399 399 PHE PHE A . n 
A 1 389 ASP 389 400 400 ASP ASP A . n 
A 1 390 ALA 390 401 401 ALA ALA A . n 
A 1 391 LEU 391 402 402 LEU LEU A . n 
A 1 392 VAL 392 403 403 VAL VAL A . n 
A 1 393 THR 393 404 404 THR THR A . n 
A 1 394 PHE 394 405 405 PHE PHE A . n 
A 1 395 CYS 395 406 406 CYS CYS A . n 
A 1 396 GLU 396 407 407 GLU GLU A . n 
A 1 397 GLU 397 408 408 GLU GLU A . n 
A 1 398 LEU 398 409 409 LEU LEU A . n 
A 1 399 GLY 399 410 410 GLY GLY A . n 
A 1 400 CYS 400 411 411 CYS CYS A . n 
A 1 401 ARG 401 412 412 ARG ARG A . n 
A 1 402 HIS 402 413 413 HIS HIS A . n 
A 1 403 ALA 403 414 414 ALA ALA A . n 
A 1 404 ALA 404 415 415 ALA ALA A . n 
A 1 405 ILE 405 416 416 ILE ILE A . n 
A 1 406 ALA 406 417 417 ALA ALA A . n 
A 1 407 LYS 407 418 418 LYS LYS A . n 
A 1 408 TYR 408 419 419 TYR TYR A . n 
A 1 409 PHE 409 420 420 PHE PHE A . n 
A 1 410 GLY 410 421 421 GLY GLY A . n 
A 1 411 ASP 411 422 422 ASP ASP A . n 
A 1 412 ALA 412 423 423 ALA ALA A . n 
A 1 413 LEU 413 424 424 LEU LEU A . n 
A 1 414 PRO 414 425 425 PRO PRO A . n 
A 1 415 ALA 415 426 426 ALA ALA A . n 
A 1 416 CYS 416 427 427 CYS CYS A . n 
A 1 417 ALA 417 428 428 ALA ALA A . n 
A 1 418 LYS 418 429 429 LYS LYS A . n 
A 1 419 GLY 419 430 430 GLY GLY A . n 
A 1 420 CYS 420 431 431 CYS CYS A . n 
A 1 421 ASP 421 432 432 ASP ASP A . n 
A 1 422 HIS 422 433 433 HIS HIS A . n 
A 1 423 CYS 423 434 434 CYS CYS A . n 
A 1 424 GLN 424 435 435 GLN GLN A . n 
A 1 425 ASN 425 436 436 ASN ASN A . n 
A 1 426 PRO 426 437 437 PRO PRO A . n 
A 1 427 THR 427 438 438 THR THR A . n 
A 1 428 ALA 428 439 439 ALA ALA A . n 
A 1 429 VAL 429 440 440 VAL VAL A . n 
A 1 430 ARG 430 441 441 ARG ARG A . n 
A 1 431 ARG 431 442 442 ARG ARG A . n 
A 1 432 ARG 432 443 443 ARG ARG A . n 
A 1 433 LEU 433 444 444 LEU LEU A . n 
A 1 434 GLU 434 445 445 GLU GLU A . n 
A 1 435 ALA 435 446 446 ALA ALA A . n 
A 1 436 LEU 436 447 447 LEU LEU A . n 
A 1 437 GLU 437 448 448 GLU GLU A . n 
A 1 438 ARG 438 449 449 ARG ARG A . n 
A 1 439 SER 439 450 450 SER SER A . n 
A 1 440 SER 440 451 451 SER SER A . n 
A 1 441 SER 441 452 ?   ?   ?   A . n 
A 1 442 TRP 442 453 ?   ?   ?   A . n 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          ZN 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    -1 
_pdbx_nonpoly_scheme.pdb_mon_id      ZN 
_pdbx_nonpoly_scheme.auth_mon_id     ZN 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A ARG 14  ? CG  ? A ARG 3   CG  
2   1 Y 1 A ARG 14  ? CD  ? A ARG 3   CD  
3   1 Y 1 A ARG 14  ? NE  ? A ARG 3   NE  
4   1 Y 1 A ARG 14  ? CZ  ? A ARG 3   CZ  
5   1 Y 1 A ARG 14  ? NH1 ? A ARG 3   NH1 
6   1 Y 1 A ARG 14  ? NH2 ? A ARG 3   NH2 
7   1 Y 1 A LYS 22  ? CG  ? A LYS 11  CG  
8   1 Y 1 A LYS 22  ? CD  ? A LYS 11  CD  
9   1 Y 1 A LYS 22  ? CE  ? A LYS 11  CE  
10  1 Y 1 A LYS 22  ? NZ  ? A LYS 11  NZ  
11  1 Y 1 A LEU 68  ? CG  ? A LEU 57  CG  
12  1 Y 1 A LEU 68  ? CD1 ? A LEU 57  CD1 
13  1 Y 1 A LEU 68  ? CD2 ? A LEU 57  CD2 
14  1 Y 1 A GLN 84  ? CG  ? A GLN 73  CG  
15  1 Y 1 A GLN 84  ? CD  ? A GLN 73  CD  
16  1 Y 1 A GLN 84  ? OE1 ? A GLN 73  OE1 
17  1 Y 1 A GLN 84  ? NE2 ? A GLN 73  NE2 
18  1 Y 1 A ARG 118 ? CG  ? A ARG 107 CG  
19  1 Y 1 A ARG 118 ? CD  ? A ARG 107 CD  
20  1 Y 1 A ARG 118 ? NE  ? A ARG 107 NE  
21  1 Y 1 A ARG 118 ? CZ  ? A ARG 107 CZ  
22  1 Y 1 A ARG 118 ? NH1 ? A ARG 107 NH1 
23  1 Y 1 A ARG 118 ? NH2 ? A ARG 107 NH2 
24  1 Y 1 A HIS 167 ? CG  ? A HIS 156 CG  
25  1 Y 1 A HIS 167 ? ND1 ? A HIS 156 ND1 
26  1 Y 1 A HIS 167 ? CD2 ? A HIS 156 CD2 
27  1 Y 1 A HIS 167 ? CE1 ? A HIS 156 CE1 
28  1 Y 1 A HIS 167 ? NE2 ? A HIS 156 NE2 
29  1 Y 1 A GLU 253 ? CG  ? A GLU 242 CG  
30  1 Y 1 A GLU 253 ? CD  ? A GLU 242 CD  
31  1 Y 1 A GLU 253 ? OE1 ? A GLU 242 OE1 
32  1 Y 1 A GLU 253 ? OE2 ? A GLU 242 OE2 
33  1 Y 1 A SER 259 ? OG  ? A SER 248 OG  
34  1 Y 1 A CYS 261 ? SG  ? A CYS 250 SG  
35  1 Y 1 A ARG 267 ? CG  ? A ARG 256 CG  
36  1 Y 1 A ARG 267 ? CD  ? A ARG 256 CD  
37  1 Y 1 A ARG 267 ? NE  ? A ARG 256 NE  
38  1 Y 1 A ARG 267 ? CZ  ? A ARG 256 CZ  
39  1 Y 1 A ARG 267 ? NH1 ? A ARG 256 NH1 
40  1 Y 1 A ARG 267 ? NH2 ? A ARG 256 NH2 
41  1 Y 1 A ARG 269 ? CG  ? A ARG 258 CG  
42  1 Y 1 A ARG 269 ? CD  ? A ARG 258 CD  
43  1 Y 1 A ARG 269 ? NE  ? A ARG 258 NE  
44  1 Y 1 A ARG 269 ? CZ  ? A ARG 258 CZ  
45  1 Y 1 A ARG 269 ? NH1 ? A ARG 258 NH1 
46  1 Y 1 A ARG 269 ? NH2 ? A ARG 258 NH2 
47  1 Y 1 A GLU 270 ? CG  ? A GLU 259 CG  
48  1 Y 1 A GLU 270 ? CD  ? A GLU 259 CD  
49  1 Y 1 A GLU 270 ? OE1 ? A GLU 259 OE1 
50  1 Y 1 A GLU 270 ? OE2 ? A GLU 259 OE2 
51  1 Y 1 A GLN 274 ? CG  ? A GLN 263 CG  
52  1 Y 1 A GLN 274 ? CD  ? A GLN 263 CD  
53  1 Y 1 A GLN 274 ? OE1 ? A GLN 263 OE1 
54  1 Y 1 A GLN 274 ? NE2 ? A GLN 263 NE2 
55  1 Y 1 A LYS 287 ? CG  ? A LYS 276 CG  
56  1 Y 1 A LYS 287 ? CD  ? A LYS 276 CD  
57  1 Y 1 A LYS 287 ? CE  ? A LYS 276 CE  
58  1 Y 1 A LYS 287 ? NZ  ? A LYS 276 NZ  
59  1 Y 1 A GLU 297 ? CG  ? A GLU 286 CG  
60  1 Y 1 A GLU 297 ? CD  ? A GLU 286 CD  
61  1 Y 1 A GLU 297 ? OE1 ? A GLU 286 OE1 
62  1 Y 1 A GLU 297 ? OE2 ? A GLU 286 OE2 
63  1 Y 1 A LYS 309 ? CG  ? A LYS 298 CG  
64  1 Y 1 A LYS 309 ? CD  ? A LYS 298 CD  
65  1 Y 1 A LYS 309 ? CE  ? A LYS 298 CE  
66  1 Y 1 A LYS 309 ? NZ  ? A LYS 298 NZ  
67  1 Y 1 A ASP 324 ? CG  ? A ASP 313 CG  
68  1 Y 1 A ASP 324 ? OD1 ? A ASP 313 OD1 
69  1 Y 1 A ASP 324 ? OD2 ? A ASP 313 OD2 
70  1 Y 1 A LYS 338 ? CG  ? A LYS 327 CG  
71  1 Y 1 A LYS 338 ? CD  ? A LYS 327 CD  
72  1 Y 1 A LYS 338 ? CE  ? A LYS 327 CE  
73  1 Y 1 A LYS 338 ? NZ  ? A LYS 327 NZ  
74  1 Y 1 A ARG 365 ? CG  ? A ARG 354 CG  
75  1 Y 1 A ARG 365 ? CD  ? A ARG 354 CD  
76  1 Y 1 A ARG 365 ? NE  ? A ARG 354 NE  
77  1 Y 1 A ARG 365 ? CZ  ? A ARG 354 CZ  
78  1 Y 1 A ARG 365 ? NH1 ? A ARG 354 NH1 
79  1 Y 1 A ARG 365 ? NH2 ? A ARG 354 NH2 
80  1 Y 1 A ASP 367 ? CG  ? A ASP 356 CG  
81  1 Y 1 A ASP 367 ? OD1 ? A ASP 356 OD1 
82  1 Y 1 A ASP 367 ? OD2 ? A ASP 356 OD2 
83  1 Y 1 A ARG 376 ? CG  ? A ARG 365 CG  
84  1 Y 1 A ARG 376 ? CD  ? A ARG 365 CD  
85  1 Y 1 A ARG 376 ? NE  ? A ARG 365 NE  
86  1 Y 1 A ARG 376 ? CZ  ? A ARG 365 CZ  
87  1 Y 1 A ARG 376 ? NH1 ? A ARG 365 NH1 
88  1 Y 1 A ARG 376 ? NH2 ? A ARG 365 NH2 
89  1 Y 1 A GLU 378 ? CG  ? A GLU 367 CG  
90  1 Y 1 A GLU 378 ? CD  ? A GLU 367 CD  
91  1 Y 1 A GLU 378 ? OE1 ? A GLU 367 OE1 
92  1 Y 1 A GLU 378 ? OE2 ? A GLU 367 OE2 
93  1 Y 1 A GLN 383 ? CG  ? A GLN 372 CG  
94  1 Y 1 A GLN 383 ? CD  ? A GLN 372 CD  
95  1 Y 1 A GLN 383 ? OE1 ? A GLN 372 OE1 
96  1 Y 1 A GLN 383 ? NE2 ? A GLN 372 NE2 
97  1 Y 1 A ASN 388 ? CG  ? A ASN 377 CG  
98  1 Y 1 A ASN 388 ? OD1 ? A ASN 377 OD1 
99  1 Y 1 A ASN 388 ? ND2 ? A ASN 377 ND2 
100 1 Y 1 A LYS 389 ? CG  ? A LYS 378 CG  
101 1 Y 1 A LYS 389 ? CD  ? A LYS 378 CD  
102 1 Y 1 A LYS 389 ? CE  ? A LYS 378 CE  
103 1 Y 1 A LYS 389 ? NZ  ? A LYS 378 NZ  
104 1 Y 1 A SER 391 ? OG  ? A SER 380 OG  
105 1 Y 1 A ASP 392 ? CG  ? A ASP 381 CG  
106 1 Y 1 A ASP 392 ? OD1 ? A ASP 381 OD1 
107 1 Y 1 A ASP 392 ? OD2 ? A ASP 381 OD2 
108 1 Y 1 A LYS 393 ? CG  ? A LYS 382 CG  
109 1 Y 1 A LYS 393 ? CD  ? A LYS 382 CD  
110 1 Y 1 A LYS 393 ? CE  ? A LYS 382 CE  
111 1 Y 1 A LYS 393 ? NZ  ? A LYS 382 NZ  
112 1 Y 1 A MET 397 ? CG  ? A MET 386 CG  
113 1 Y 1 A MET 397 ? SD  ? A MET 386 SD  
114 1 Y 1 A MET 397 ? CE  ? A MET 386 CE  
115 1 Y 1 A GLU 408 ? CG  ? A GLU 397 CG  
116 1 Y 1 A GLU 408 ? CD  ? A GLU 397 CD  
117 1 Y 1 A GLU 408 ? OE1 ? A GLU 397 OE1 
118 1 Y 1 A GLU 408 ? OE2 ? A GLU 397 OE2 
119 1 Y 1 A GLN 435 ? CG  ? A GLN 424 CG  
120 1 Y 1 A GLN 435 ? CD  ? A GLN 424 CD  
121 1 Y 1 A GLN 435 ? OE1 ? A GLN 424 OE1 
122 1 Y 1 A GLN 435 ? NE2 ? A GLN 424 NE2 
123 1 Y 1 A VAL 440 ? CG1 ? A VAL 429 CG1 
124 1 Y 1 A VAL 440 ? CG2 ? A VAL 429 CG2 
125 1 Y 1 A ARG 443 ? CG  ? A ARG 432 CG  
126 1 Y 1 A ARG 443 ? CD  ? A ARG 432 CD  
127 1 Y 1 A ARG 443 ? NE  ? A ARG 432 NE  
128 1 Y 1 A ARG 443 ? CZ  ? A ARG 432 CZ  
129 1 Y 1 A ARG 443 ? NH1 ? A ARG 432 NH1 
130 1 Y 1 A ARG 443 ? NH2 ? A ARG 432 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8RL6 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8RL6 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8RL6 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8RL6 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 3343 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.483 ? 4534 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.792 ? 469  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.037 ? 525  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 581  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8RL6 
_struct.title                        'DNA helicase RECQL5 in complex with homo Di-Gluebody G5-006 - RECQL5 local refinement' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8RL6 
_struct_keywords.text            'DNA helicase, Di-Gluebody, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    RECQ5_HUMAN 
_struct_ref.pdbx_db_accession          O94762 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;PERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQVDHLL
TLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRP
DYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALG
QEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFV
AHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGC
RHAAIAKYFGDALPACAKGCDHCQNPTAVRRRLEALERSSSW
;
_struct_ref.pdbx_align_begin           12 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8RL6 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 442 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             O94762 
_struct_ref_seq.db_align_beg                  12 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  453 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       12 
_struct_ref_seq.pdbx_auth_seq_align_end       453 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 1   ? GLY A 14  ? PRO A 12  GLY A 25  1 ? 14 
HELX_P HELX_P2  AA2 THR A 20  ? GLY A 33  ? THR A 31  GLY A 44  1 ? 14 
HELX_P HELX_P3  AA3 GLY A 46  ? ALA A 58  ? GLY A 57  ALA A 69  1 ? 13 
HELX_P HELX_P4  AA4 LEU A 68  ? LEU A 82  ? LEU A 79  LEU A 93  1 ? 15 
HELX_P HELX_P5  AA5 SER A 94  ? ARG A 107 ? SER A 105 ARG A 118 1 ? 14 
HELX_P HELX_P6  AA6 THR A 118 ? ALA A 123 ? THR A 129 ALA A 134 1 ? 6  
HELX_P HELX_P7  AA7 SER A 126 ? ARG A 137 ? SER A 137 ARG A 148 1 ? 12 
HELX_P HELX_P8  AA8 GLU A 147 ? SER A 152 ? GLU A 158 SER A 163 5 ? 6  
HELX_P HELX_P9  AA9 ARG A 159 ? ARG A 171 ? ARG A 170 ARG A 182 1 ? 13 
HELX_P HELX_P10 AB1 THR A 185 ? LEU A 196 ? THR A 196 LEU A 207 1 ? 12 
HELX_P HELX_P11 AB2 ASP A 226 ? GLY A 240 ? ASP A 237 GLY A 251 1 ? 15 
HELX_P HELX_P12 AB3 THR A 257 ? GLY A 272 ? THR A 268 GLY A 283 1 ? 16 
HELX_P HELX_P13 AB4 LYS A 283 ? GLU A 296 ? LYS A 294 GLU A 307 1 ? 14 
HELX_P HELX_P14 AB5 SER A 328 ? ARG A 338 ? SER A 339 ARG A 349 1 ? 11 
HELX_P HELX_P15 AB6 SER A 353 ? LYS A 374 ? SER A 364 LYS A 385 1 ? 22 
HELX_P HELX_P16 AB7 ASN A 377 ? GLU A 396 ? ASN A 388 GLU A 407 1 ? 20 
HELX_P HELX_P17 AB8 CYS A 400 ? GLY A 410 ? CYS A 411 GLY A 421 1 ? 11 
HELX_P HELX_P18 AB9 ASN A 425 ? SER A 440 ? ASN A 436 SER A 451 1 ? 16 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 255 SG ? ? ? 1_555 A CYS 261 SG ? ? A CYS 266 A CYS 272 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
metalc1 metalc ? ? A CYS 400 SG ? ? ? 1_555 B ZN  .   ZN ? ? A CYS 411 A ZN  501 1_555 ? ? ? ? ? ? ? 2.331 ? ? 
metalc2 metalc ? ? A CYS 416 SG ? ? ? 1_555 B ZN  .   ZN ? ? A CYS 427 A ZN  501 1_555 ? ? ? ? ? ? ? 2.361 ? ? 
metalc3 metalc ? ? A CYS 420 SG ? ? ? 1_555 B ZN  .   ZN ? ? A CYS 431 A ZN  501 1_555 ? ? ? ? ? ? ? 2.339 ? ? 
metalc4 metalc ? ? A CYS 423 SG ? ? ? 1_555 B ZN  .   ZN ? ? A CYS 434 A ZN  501 1_555 ? ? ? ? ? ? ? 2.347 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 SG ? A CYS 400 ? A CYS 411 ? 1_555 ZN ? B ZN . ? A ZN 501 ? 1_555 SG ? A CYS 416 ? A CYS 427 ? 1_555 110.0 ? 
2 SG ? A CYS 400 ? A CYS 411 ? 1_555 ZN ? B ZN . ? A ZN 501 ? 1_555 SG ? A CYS 420 ? A CYS 431 ? 1_555 107.5 ? 
3 SG ? A CYS 416 ? A CYS 427 ? 1_555 ZN ? B ZN . ? A ZN 501 ? 1_555 SG ? A CYS 420 ? A CYS 431 ? 1_555 110.1 ? 
4 SG ? A CYS 400 ? A CYS 411 ? 1_555 ZN ? B ZN . ? A ZN 501 ? 1_555 SG ? A CYS 423 ? A CYS 434 ? 1_555 99.1  ? 
5 SG ? A CYS 416 ? A CYS 427 ? 1_555 ZN ? B ZN . ? A ZN 501 ? 1_555 SG ? A CYS 423 ? A CYS 434 ? 1_555 122.1 ? 
6 SG ? A CYS 420 ? A CYS 431 ? 1_555 ZN ? B ZN . ? A ZN 501 ? 1_555 SG ? A CYS 423 ? A CYS 434 ? 1_555 106.9 ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       255 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      261 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        266 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       272 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA1 3 4 ? parallel 
AA1 4 5 ? parallel 
AA1 5 6 ? parallel 
AA1 6 7 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
AA2 4 5 ? parallel 
AA2 5 6 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 86  ? LEU A 89  ? VAL A 97  LEU A 100 
AA1 2 ILE A 114 ? ILE A 117 ? ILE A 125 ILE A 128 
AA1 3 ILE A 61  ? VAL A 65  ? ILE A 72  VAL A 76  
AA1 4 LEU A 140 ? VAL A 145 ? LEU A 151 VAL A 156 
AA1 5 CYS A 177 ? THR A 181 ? CYS A 188 THR A 192 
AA1 6 ASP A 36  ? CYS A 40  ? ASP A 47  CYS A 51  
AA1 7 VAL A 202 ? ALA A 203 ? VAL A 213 ALA A 214 
AA2 1 LEU A 214 ? PHE A 220 ? LEU A 225 PHE A 231 
AA2 2 SER A 346 ? TYR A 352 ? SER A 357 TYR A 363 
AA2 3 PHE A 319 ? HIS A 322 ? PHE A 330 HIS A 333 
AA2 4 GLY A 251 ? CYS A 255 ? GLY A 262 CYS A 266 
AA2 5 VAL A 301 ? THR A 305 ? VAL A 312 THR A 316 
AA2 6 ALA A 277 ? TYR A 278 ? ALA A 288 TYR A 289 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 87  ? N SER A 98  O TYR A 116 ? O TYR A 127 
AA1 2 3 O ILE A 117 ? O ILE A 128 N VAL A 64  ? N VAL A 75  
AA1 3 4 N ILE A 63  ? N ILE A 74  O VAL A 144 ? O VAL A 155 
AA1 4 5 N VAL A 145 ? N VAL A 156 O LEU A 180 ? O LEU A 191 
AA1 5 6 O CYS A 177 ? O CYS A 188 N VAL A 37  ? N VAL A 48  
AA1 6 7 N PHE A 38  ? N PHE A 49  O ALA A 203 ? O ALA A 214 
AA2 1 2 N PHE A 215 ? N PHE A 226 O CYS A 348 ? O CYS A 359 
AA2 2 3 O TYR A 351 ? O TYR A 362 N HIS A 322 ? N HIS A 333 
AA2 3 4 O ALA A 321 ? O ALA A 332 N ILE A 252 ? N ILE A 263 
AA2 4 5 N VAL A 253 ? N VAL A 264 O ALA A 304 ? O ALA A 315 
AA2 5 6 O THR A 305 ? O THR A 316 N TYR A 278 ? N TYR A 289 
# 
_pdbx_entry_details.entry_id                   8RL6 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 407 ? ? -100.03 67.46 
2 1 ASN A 436 ? ? 34.91   51.33 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8RL6 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   157.2 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  7ZMV 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                7ZMV 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    8RL6 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.18 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               194417 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          4 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Local refinement of the RECQL5 part of RECQL5 homodimer assembled by G5-006 homo Di-Gluebody' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8RL6 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   200 
_em_sample_support.grid_type        C-flat-2/1 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8RL6 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8RL6 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8RL6 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY 320 ? A GLY 309 
2 1 Y 1 A MET 321 ? A MET 310 
3 1 Y 1 A GLY 322 ? A GLY 311 
4 1 Y 1 A VAL 323 ? A VAL 312 
5 1 Y 1 A SER 452 ? A SER 441 
6 1 Y 1 A TRP 453 ? A TRP 442 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
PHE N    N  N N 247 
PHE CA   C  N S 248 
PHE C    C  N N 249 
PHE O    O  N N 250 
PHE CB   C  N N 251 
PHE CG   C  Y N 252 
PHE CD1  C  Y N 253 
PHE CD2  C  Y N 254 
PHE CE1  C  Y N 255 
PHE CE2  C  Y N 256 
PHE CZ   C  Y N 257 
PHE OXT  O  N N 258 
PHE H    H  N N 259 
PHE H2   H  N N 260 
PHE HA   H  N N 261 
PHE HB2  H  N N 262 
PHE HB3  H  N N 263 
PHE HD1  H  N N 264 
PHE HD2  H  N N 265 
PHE HE1  H  N N 266 
PHE HE2  H  N N 267 
PHE HZ   H  N N 268 
PHE HXT  H  N N 269 
PRO N    N  N N 270 
PRO CA   C  N S 271 
PRO C    C  N N 272 
PRO O    O  N N 273 
PRO CB   C  N N 274 
PRO CG   C  N N 275 
PRO CD   C  N N 276 
PRO OXT  O  N N 277 
PRO H    H  N N 278 
PRO HA   H  N N 279 
PRO HB2  H  N N 280 
PRO HB3  H  N N 281 
PRO HG2  H  N N 282 
PRO HG3  H  N N 283 
PRO HD2  H  N N 284 
PRO HD3  H  N N 285 
PRO HXT  H  N N 286 
SER N    N  N N 287 
SER CA   C  N S 288 
SER C    C  N N 289 
SER O    O  N N 290 
SER CB   C  N N 291 
SER OG   O  N N 292 
SER OXT  O  N N 293 
SER H    H  N N 294 
SER H2   H  N N 295 
SER HA   H  N N 296 
SER HB2  H  N N 297 
SER HB3  H  N N 298 
SER HG   H  N N 299 
SER HXT  H  N N 300 
THR N    N  N N 301 
THR CA   C  N S 302 
THR C    C  N N 303 
THR O    O  N N 304 
THR CB   C  N R 305 
THR OG1  O  N N 306 
THR CG2  C  N N 307 
THR OXT  O  N N 308 
THR H    H  N N 309 
THR H2   H  N N 310 
THR HA   H  N N 311 
THR HB   H  N N 312 
THR HG1  H  N N 313 
THR HG21 H  N N 314 
THR HG22 H  N N 315 
THR HG23 H  N N 316 
THR HXT  H  N N 317 
TRP N    N  N N 318 
TRP CA   C  N S 319 
TRP C    C  N N 320 
TRP O    O  N N 321 
TRP CB   C  N N 322 
TRP CG   C  Y N 323 
TRP CD1  C  Y N 324 
TRP CD2  C  Y N 325 
TRP NE1  N  Y N 326 
TRP CE2  C  Y N 327 
TRP CE3  C  Y N 328 
TRP CZ2  C  Y N 329 
TRP CZ3  C  Y N 330 
TRP CH2  C  Y N 331 
TRP OXT  O  N N 332 
TRP H    H  N N 333 
TRP H2   H  N N 334 
TRP HA   H  N N 335 
TRP HB2  H  N N 336 
TRP HB3  H  N N 337 
TRP HD1  H  N N 338 
TRP HE1  H  N N 339 
TRP HE3  H  N N 340 
TRP HZ2  H  N N 341 
TRP HZ3  H  N N 342 
TRP HH2  H  N N 343 
TRP HXT  H  N N 344 
TYR N    N  N N 345 
TYR CA   C  N S 346 
TYR C    C  N N 347 
TYR O    O  N N 348 
TYR CB   C  N N 349 
TYR CG   C  Y N 350 
TYR CD1  C  Y N 351 
TYR CD2  C  Y N 352 
TYR CE1  C  Y N 353 
TYR CE2  C  Y N 354 
TYR CZ   C  Y N 355 
TYR OH   O  N N 356 
TYR OXT  O  N N 357 
TYR H    H  N N 358 
TYR H2   H  N N 359 
TYR HA   H  N N 360 
TYR HB2  H  N N 361 
TYR HB3  H  N N 362 
TYR HD1  H  N N 363 
TYR HD2  H  N N 364 
TYR HE1  H  N N 365 
TYR HE2  H  N N 366 
TYR HH   H  N N 367 
TYR HXT  H  N N 368 
VAL N    N  N N 369 
VAL CA   C  N S 370 
VAL C    C  N N 371 
VAL O    O  N N 372 
VAL CB   C  N N 373 
VAL CG1  C  N N 374 
VAL CG2  C  N N 375 
VAL OXT  O  N N 376 
VAL H    H  N N 377 
VAL H2   H  N N 378 
VAL HA   H  N N 379 
VAL HB   H  N N 380 
VAL HG11 H  N N 381 
VAL HG12 H  N N 382 
VAL HG13 H  N N 383 
VAL HG21 H  N N 384 
VAL HG22 H  N N 385 
VAL HG23 H  N N 386 
VAL HXT  H  N N 387 
ZN  ZN   ZN N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-02 
_em_admin.deposition_site    PDBE 
_em_admin.entry_id           8RL6 
_em_admin.last_update        2025-01-15 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'DNA helicase RECQL5 in complex with homo Di-Gluebody G5-006 - RECQL5 local refinement' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20  mM C8H18N2O4S 1 HEPES             
1 150 mM NaCl       2 'sodium chloride' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.126 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     9247 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   610675 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC      4.0 
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU            ?   
MASKING                    ? 3  ? ? ? ?              ?   
'CTF CORRECTION'           ? 4  1 ? ? cryoSPARC      4.0 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?              ?   
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?              ?   
'MODEL FITTING'            ? 7  ? 1 ? 'UCSF Chimera' ?   
OTHER                      ? 8  ? ? ? ?              ?   
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX         ?   
'MODEL REFINEMENT'         ? 10 ? 1 ? Coot           ?   
'INITIAL EULER ASSIGNMENT' ? 11 1 ? ? cryoSPARC      4.0 
'FINAL EULER ASSIGNMENT'   ? 12 1 ? ? cryoSPARC      4.0 
CLASSIFICATION             ? 13 1 ? ? cryoSPARC      4.0 
RECONSTRUCTION             ? 14 1 ? ? cryoSPARC      4.0 
# 
_em_specimen.concentration           0.8 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7ZMV 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8RL6 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
H  
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . PRO A 1 1   ? 137.818 153.545 160.519 1.00 46.21  ? 12  PRO A N    1 
ATOM   2    C  CA   . PRO A 1 1   ? 136.352 153.596 160.512 1.00 56.07  ? 12  PRO A CA   1 
ATOM   3    C  C    . PRO A 1 1   ? 135.803 154.975 160.865 1.00 59.75  ? 12  PRO A C    1 
ATOM   4    O  O    . PRO A 1 1   ? 136.420 155.706 161.639 1.00 63.78  ? 12  PRO A O    1 
ATOM   5    C  CB   . PRO A 1 1   ? 135.961 152.563 161.574 1.00 47.48  ? 12  PRO A CB   1 
ATOM   6    C  CG   . PRO A 1 1   ? 137.096 151.611 161.604 1.00 50.80  ? 12  PRO A CG   1 
ATOM   7    C  CD   . PRO A 1 1   ? 138.325 152.429 161.334 1.00 49.24  ? 12  PRO A CD   1 
ATOM   8    H  HA   . PRO A 1 1   ? 136.006 153.320 159.649 1.00 55.34  ? 12  PRO A HA   1 
ATOM   9    H  HB2  . PRO A 1 1   ? 135.855 153.000 162.434 1.00 52.81  ? 12  PRO A HB2  1 
ATOM   10   H  HB3  . PRO A 1 1   ? 135.142 152.115 161.311 1.00 53.48  ? 12  PRO A HB3  1 
ATOM   11   H  HG2  . PRO A 1 1   ? 137.149 151.196 162.479 1.00 54.90  ? 12  PRO A HG2  1 
ATOM   12   H  HG3  . PRO A 1 1   ? 136.976 150.939 160.915 1.00 54.09  ? 12  PRO A HG3  1 
ATOM   13   H  HD2  . PRO A 1 1   ? 138.700 152.760 162.165 1.00 54.70  ? 12  PRO A HD2  1 
ATOM   14   H  HD3  . PRO A 1 1   ? 138.973 151.910 160.832 1.00 53.79  ? 12  PRO A HD3  1 
ATOM   15   N  N    . GLU A 1 2   ? 134.645 155.318 160.296 1.00 83.26  ? 13  GLU A N    1 
ATOM   16   C  CA   . GLU A 1 2   ? 134.058 156.630 160.549 1.00 86.19  ? 13  GLU A CA   1 
ATOM   17   C  C    . GLU A 1 2   ? 133.741 156.813 162.028 1.00 91.06  ? 13  GLU A C    1 
ATOM   18   O  O    . GLU A 1 2   ? 133.984 157.885 162.594 1.00 88.83  ? 13  GLU A O    1 
ATOM   19   C  CB   . GLU A 1 2   ? 132.797 156.808 159.702 1.00 88.25  ? 13  GLU A CB   1 
ATOM   20   C  CG   . GLU A 1 2   ? 132.084 158.143 159.895 1.00 86.58  ? 13  GLU A CG   1 
ATOM   21   C  CD   . GLU A 1 2   ? 132.855 159.308 159.305 1.00 83.83  ? 13  GLU A CD   1 
ATOM   22   O  OE1  . GLU A 1 2   ? 133.537 159.113 158.278 1.00 83.37  ? 13  GLU A OE1  1 
ATOM   23   O  OE2  . GLU A 1 2   ? 132.777 160.420 159.869 1.00 84.16  ? 13  GLU A OE2  1 
ATOM   24   H  H    . GLU A 1 2   ? 134.189 154.817 159.766 1.00 84.47  ? 13  GLU A H    1 
ATOM   25   H  HA   . GLU A 1 2   ? 134.693 157.316 160.291 1.00 84.43  ? 13  GLU A HA   1 
ATOM   26   H  HB2  . GLU A 1 2   ? 133.040 156.737 158.765 1.00 85.46  ? 13  GLU A HB2  1 
ATOM   27   H  HB3  . GLU A 1 2   ? 132.169 156.105 159.930 1.00 85.79  ? 13  GLU A HB3  1 
ATOM   28   H  HG2  . GLU A 1 2   ? 131.223 158.104 159.451 1.00 85.69  ? 13  GLU A HG2  1 
ATOM   29   H  HG3  . GLU A 1 2   ? 131.958 158.313 160.841 1.00 85.85  ? 13  GLU A HG3  1 
ATOM   30   N  N    . ARG A 1 3   ? 133.191 155.780 162.670 1.00 100.07 ? 14  ARG A N    1 
ATOM   31   C  CA   . ARG A 1 3   ? 132.851 155.888 164.086 1.00 96.73  ? 14  ARG A CA   1 
ATOM   32   C  C    . ARG A 1 3   ? 134.094 156.107 164.939 1.00 96.40  ? 14  ARG A C    1 
ATOM   33   O  O    . ARG A 1 3   ? 134.081 156.921 165.871 1.00 93.55  ? 14  ARG A O    1 
ATOM   34   C  CB   . ARG A 1 3   ? 132.105 154.633 164.540 1.00 94.68  ? 14  ARG A CB   1 
ATOM   35   H  H    . ARG A 1 3   ? 133.007 155.019 162.314 1.00 95.15  ? 14  ARG A H    1 
ATOM   36   H  HA   . ARG A 1 3   ? 132.263 156.649 164.211 1.00 95.37  ? 14  ARG A HA   1 
ATOM   37   N  N    . ARG A 1 4   ? 135.177 155.386 164.641 1.00 86.03  ? 15  ARG A N    1 
ATOM   38   C  CA   . ARG A 1 4   ? 136.405 155.543 165.414 1.00 80.07  ? 15  ARG A CA   1 
ATOM   39   C  C    . ARG A 1 4   ? 136.940 156.964 165.305 1.00 75.89  ? 15  ARG A C    1 
ATOM   40   O  O    . ARG A 1 4   ? 137.315 157.577 166.310 1.00 79.50  ? 15  ARG A O    1 
ATOM   41   C  CB   . ARG A 1 4   ? 137.458 154.541 164.940 1.00 82.89  ? 15  ARG A CB   1 
ATOM   42   C  CG   . ARG A 1 4   ? 138.817 154.716 165.608 1.00 81.29  ? 15  ARG A CG   1 
ATOM   43   C  CD   . ARG A 1 4   ? 139.817 153.672 165.144 1.00 80.27  ? 15  ARG A CD   1 
ATOM   44   N  NE   . ARG A 1 4   ? 141.174 153.999 165.565 1.00 82.55  ? 15  ARG A NE   1 
ATOM   45   C  CZ   . ARG A 1 4   ? 141.610 153.934 166.816 1.00 82.20  ? 15  ARG A CZ   1 
ATOM   46   N  NH1  . ARG A 1 4   ? 140.818 153.556 167.807 1.00 79.70  ? 15  ARG A NH1  1 
ATOM   47   N  NH2  . ARG A 1 4   ? 142.872 154.260 167.082 1.00 86.20  ? 15  ARG A NH2  1 
ATOM   48   H  H    . ARG A 1 4   ? 135.225 154.808 164.005 1.00 81.07  ? 15  ARG A H    1 
ATOM   49   H  HA   . ARG A 1 4   ? 136.217 155.363 166.348 1.00 80.75  ? 15  ARG A HA   1 
ATOM   50   H  HB2  . ARG A 1 4   ? 137.146 153.643 165.133 1.00 80.66  ? 15  ARG A HB2  1 
ATOM   51   H  HB3  . ARG A 1 4   ? 137.582 154.647 163.983 1.00 80.27  ? 15  ARG A HB3  1 
ATOM   52   H  HG2  . ARG A 1 4   ? 139.177 155.588 165.385 1.00 80.40  ? 15  ARG A HG2  1 
ATOM   53   H  HG3  . ARG A 1 4   ? 138.712 154.633 166.569 1.00 80.74  ? 15  ARG A HG3  1 
ATOM   54   H  HD2  . ARG A 1 4   ? 139.580 152.812 165.525 1.00 80.32  ? 15  ARG A HD2  1 
ATOM   55   H  HD3  . ARG A 1 4   ? 139.803 153.625 164.176 1.00 80.41  ? 15  ARG A HD3  1 
ATOM   56   H  HE   . ARG A 1 4   ? 141.727 154.267 164.963 1.00 81.32  ? 15  ARG A HE   1 
ATOM   57   H  HH11 . ARG A 1 4   ? 140.000 153.343 167.649 1.00 80.26  ? 15  ARG A HH11 1 
ATOM   58   H  HH12 . ARG A 1 4   ? 141.122 153.522 168.610 1.00 80.80  ? 15  ARG A HH12 1 
ATOM   59   H  HH21 . ARG A 1 4   ? 143.395 154.507 166.446 1.00 81.16  ? 15  ARG A HH21 1 
ATOM   60   H  HH22 . ARG A 1 4   ? 143.165 154.222 167.889 1.00 81.80  ? 15  ARG A HH22 1 
ATOM   61   N  N    . VAL A 1 5   ? 136.986 157.504 164.087 1.00 71.83  ? 16  VAL A N    1 
ATOM   62   C  CA   . VAL A 1 5   ? 137.502 158.854 163.898 1.00 73.10  ? 16  VAL A CA   1 
ATOM   63   C  C    . VAL A 1 5   ? 136.582 159.875 164.553 1.00 80.37  ? 16  VAL A C    1 
ATOM   64   O  O    . VAL A 1 5   ? 137.045 160.869 165.123 1.00 85.79  ? 16  VAL A O    1 
ATOM   65   C  CB   . VAL A 1 5   ? 137.701 159.143 162.400 1.00 77.70  ? 16  VAL A CB   1 
ATOM   66   C  CG1  . VAL A 1 5   ? 138.208 160.561 162.203 1.00 77.17  ? 16  VAL A CG1  1 
ATOM   67   C  CG2  . VAL A 1 5   ? 138.676 158.142 161.793 1.00 80.35  ? 16  VAL A CG2  1 
ATOM   68   H  H    . VAL A 1 5   ? 136.729 157.114 163.365 1.00 77.86  ? 16  VAL A H    1 
ATOM   69   H  HA   . VAL A 1 5   ? 138.369 158.920 164.328 1.00 77.72  ? 16  VAL A HA   1 
ATOM   70   H  HB   . VAL A 1 5   ? 136.850 159.055 161.944 1.00 78.46  ? 16  VAL A HB   1 
ATOM   71   H  HG11 . VAL A 1 5   ? 138.590 160.640 161.315 1.00 77.92  ? 16  VAL A HG11 1 
ATOM   72   H  HG12 . VAL A 1 5   ? 137.467 161.180 162.300 1.00 77.85  ? 16  VAL A HG12 1 
ATOM   73   H  HG13 . VAL A 1 5   ? 138.887 160.745 162.870 1.00 78.00  ? 16  VAL A HG13 1 
ATOM   74   H  HG21 . VAL A 1 5   ? 138.786 158.340 160.850 1.00 78.37  ? 16  VAL A HG21 1 
ATOM   75   H  HG22 . VAL A 1 5   ? 139.529 158.219 162.249 1.00 78.46  ? 16  VAL A HG22 1 
ATOM   76   H  HG23 . VAL A 1 5   ? 138.323 157.246 161.903 1.00 77.97  ? 16  VAL A HG23 1 
ATOM   77   N  N    . ARG A 1 6   ? 135.268 159.653 164.483 1.00 87.05  ? 17  ARG A N    1 
ATOM   78   C  CA   . ARG A 1 6   ? 134.324 160.556 165.136 1.00 86.73  ? 17  ARG A CA   1 
ATOM   79   C  C    . ARG A 1 6   ? 134.576 160.596 166.640 1.00 89.52  ? 17  ARG A C    1 
ATOM   80   O  O    . ARG A 1 6   ? 134.677 161.674 167.247 1.00 87.54  ? 17  ARG A O    1 
ATOM   81   C  CB   . ARG A 1 6   ? 132.897 160.087 164.845 1.00 85.07  ? 17  ARG A CB   1 
ATOM   82   C  CG   . ARG A 1 6   ? 131.788 160.977 165.393 1.00 87.85  ? 17  ARG A CG   1 
ATOM   83   C  CD   . ARG A 1 6   ? 131.707 162.299 164.644 1.00 85.99  ? 17  ARG A CD   1 
ATOM   84   N  NE   . ARG A 1 6   ? 131.637 162.089 163.201 1.00 87.82  ? 17  ARG A NE   1 
ATOM   85   C  CZ   . ARG A 1 6   ? 131.553 163.060 162.303 1.00 91.50  ? 17  ARG A CZ   1 
ATOM   86   N  NH1  . ARG A 1 6   ? 131.505 164.330 162.662 1.00 92.89  ? 17  ARG A NH1  1 
ATOM   87   N  NH2  . ARG A 1 6   ? 131.510 162.747 161.011 1.00 89.80  ? 17  ARG A NH2  1 
ATOM   88   H  H    . ARG A 1 6   ? 134.903 158.995 164.068 1.00 87.10  ? 17  ARG A H    1 
ATOM   89   H  HA   . ARG A 1 6   ? 134.434 161.452 164.781 1.00 87.38  ? 17  ARG A HA   1 
ATOM   90   H  HB2  . ARG A 1 6   ? 132.785 160.018 163.885 1.00 86.92  ? 17  ARG A HB2  1 
ATOM   91   H  HB3  . ARG A 1 6   ? 132.781 159.210 165.243 1.00 87.71  ? 17  ARG A HB3  1 
ATOM   92   H  HG2  . ARG A 1 6   ? 130.937 160.523 165.294 1.00 87.79  ? 17  ARG A HG2  1 
ATOM   93   H  HG3  . ARG A 1 6   ? 131.957 161.168 166.328 1.00 88.23  ? 17  ARG A HG3  1 
ATOM   94   H  HD2  . ARG A 1 6   ? 130.907 162.774 164.920 1.00 87.50  ? 17  ARG A HD2  1 
ATOM   95   H  HD3  . ARG A 1 6   ? 132.496 162.828 164.838 1.00 87.20  ? 17  ARG A HD3  1 
ATOM   96   H  HE   . ARG A 1 6   ? 131.477 161.290 162.928 1.00 87.60  ? 17  ARG A HE   1 
ATOM   97   H  HH11 . ARG A 1 6   ? 131.530 164.537 163.494 1.00 88.14  ? 17  ARG A HH11 1 
ATOM   98   H  HH12 . ARG A 1 6   ? 131.448 164.947 162.065 1.00 88.40  ? 17  ARG A HH12 1 
ATOM   99   H  HH21 . ARG A 1 6   ? 131.540 161.923 160.766 1.00 87.86  ? 17  ARG A HH21 1 
ATOM   100  H  HH22 . ARG A 1 6   ? 131.453 163.369 160.421 1.00 88.30  ? 17  ARG A HH22 1 
ATOM   101  N  N    . SER A 1 7   ? 134.690 159.416 167.255 1.00 100.34 ? 18  SER A N    1 
ATOM   102  C  CA   . SER A 1 7   ? 134.929 159.340 168.691 1.00 102.59 ? 18  SER A CA   1 
ATOM   103  C  C    . SER A 1 7   ? 136.273 159.954 169.058 1.00 98.24  ? 18  SER A C    1 
ATOM   104  O  O    . SER A 1 7   ? 136.390 160.636 170.081 1.00 96.53  ? 18  SER A O    1 
ATOM   105  C  CB   . SER A 1 7   ? 134.862 157.886 169.155 1.00 101.32 ? 18  SER A CB   1 
ATOM   106  O  OG   . SER A 1 7   ? 135.933 157.131 168.616 1.00 100.52 ? 18  SER A OG   1 
ATOM   107  H  H    . SER A 1 7   ? 134.630 158.652 166.863 1.00 97.75  ? 18  SER A H    1 
ATOM   108  H  HA   . SER A 1 7   ? 134.236 159.836 169.154 1.00 99.00  ? 18  SER A HA   1 
ATOM   109  H  HB2  . SER A 1 7   ? 134.916 157.862 170.123 1.00 98.62  ? 18  SER A HB2  1 
ATOM   110  H  HB3  . SER A 1 7   ? 134.023 157.499 168.860 1.00 98.73  ? 18  SER A HB3  1 
ATOM   111  H  HG   . SER A 1 7   ? 135.896 157.138 167.777 1.00 97.73  ? 18  SER A HG   1 
ATOM   112  N  N    . THR A 1 8   ? 137.302 159.714 168.243 1.00 82.98  ? 19  THR A N    1 
ATOM   113  C  CA   . THR A 1 8   ? 138.610 160.295 168.522 1.00 80.87  ? 19  THR A CA   1 
ATOM   114  C  C    . THR A 1 8   ? 138.560 161.814 168.437 1.00 80.30  ? 19  THR A C    1 
ATOM   115  O  O    . THR A 1 8   ? 139.169 162.510 169.258 1.00 84.36  ? 19  THR A O    1 
ATOM   116  C  CB   . THR A 1 8   ? 139.651 159.739 167.549 1.00 82.87  ? 19  THR A CB   1 
ATOM   117  O  OG1  . THR A 1 8   ? 139.750 158.319 167.712 1.00 82.39  ? 19  THR A OG1  1 
ATOM   118  C  CG2  . THR A 1 8   ? 141.014 160.369 167.803 1.00 80.79  ? 19  THR A CG2  1 
ATOM   119  H  H    . THR A 1 8   ? 137.269 159.226 167.536 1.00 83.10  ? 19  THR A H    1 
ATOM   120  H  HA   . THR A 1 8   ? 138.880 160.052 169.421 1.00 82.37  ? 19  THR A HA   1 
ATOM   121  H  HB   . THR A 1 8   ? 139.383 159.942 166.639 1.00 82.22  ? 19  THR A HB   1 
ATOM   122  H  HG1  . THR A 1 8   ? 140.298 158.004 167.158 1.00 81.41  ? 19  THR A HG1  1 
ATOM   123  H  HG21 . THR A 1 8   ? 141.697 159.884 167.313 1.00 81.74  ? 19  THR A HG21 1 
ATOM   124  H  HG22 . THR A 1 8   ? 141.017 161.294 167.512 1.00 81.37  ? 19  THR A HG22 1 
ATOM   125  H  HG23 . THR A 1 8   ? 141.224 160.335 168.750 1.00 81.74  ? 19  THR A HG23 1 
ATOM   126  N  N    . LEU A 1 9   ? 137.843 162.347 167.446 1.00 73.52  ? 20  LEU A N    1 
ATOM   127  C  CA   . LEU A 1 9   ? 137.708 163.793 167.331 1.00 78.49  ? 20  LEU A CA   1 
ATOM   128  C  C    . LEU A 1 9   ? 137.021 164.370 168.558 1.00 87.80  ? 20  LEU A C    1 
ATOM   129  O  O    . LEU A 1 9   ? 137.458 165.391 169.102 1.00 92.30  ? 20  LEU A O    1 
ATOM   130  C  CB   . LEU A 1 9   ? 136.925 164.147 166.067 1.00 77.77  ? 20  LEU A CB   1 
ATOM   131  C  CG   . LEU A 1 9   ? 136.580 165.625 165.870 1.00 79.91  ? 20  LEU A CG   1 
ATOM   132  C  CD1  . LEU A 1 9   ? 137.840 166.430 165.609 1.00 80.49  ? 20  LEU A CD1  1 
ATOM   133  C  CD2  . LEU A 1 9   ? 135.588 165.798 164.735 1.00 81.24  ? 20  LEU A CD2  1 
ATOM   134  H  H    . LEU A 1 9   ? 137.433 161.899 166.838 1.00 80.66  ? 20  LEU A H    1 
ATOM   135  H  HA   . LEU A 1 9   ? 138.589 164.192 167.263 1.00 81.06  ? 20  LEU A HA   1 
ATOM   136  H  HB2  . LEU A 1 9   ? 137.445 163.870 165.298 1.00 80.88  ? 20  LEU A HB2  1 
ATOM   137  H  HB3  . LEU A 1 9   ? 136.088 163.657 166.081 1.00 81.04  ? 20  LEU A HB3  1 
ATOM   138  H  HG   . LEU A 1 9   ? 136.168 165.970 166.676 1.00 81.41  ? 20  LEU A HG   1 
ATOM   139  H  HD11 . LEU A 1 9   ? 137.597 167.355 165.446 1.00 81.31  ? 20  LEU A HD11 1 
ATOM   140  H  HD12 . LEU A 1 9   ? 138.422 166.370 166.382 1.00 81.02  ? 20  LEU A HD12 1 
ATOM   141  H  HD13 . LEU A 1 9   ? 138.284 166.063 164.829 1.00 81.30  ? 20  LEU A HD13 1 
ATOM   142  H  HD21 . LEU A 1 9   ? 135.440 166.745 164.587 1.00 81.43  ? 20  LEU A HD21 1 
ATOM   143  H  HD22 . LEU A 1 9   ? 135.956 165.392 163.936 1.00 80.83  ? 20  LEU A HD22 1 
ATOM   144  H  HD23 . LEU A 1 9   ? 134.754 165.365 164.976 1.00 81.34  ? 20  LEU A HD23 1 
ATOM   145  N  N    . LYS A 1 10  ? 135.942 163.730 169.012 1.00 90.07  ? 21  LYS A N    1 
ATOM   146  C  CA   . LYS A 1 10  ? 135.259 164.233 170.201 1.00 92.12  ? 21  LYS A CA   1 
ATOM   147  C  C    . LYS A 1 10  ? 136.141 164.128 171.440 1.00 90.61  ? 21  LYS A C    1 
ATOM   148  O  O    . LYS A 1 10  ? 136.147 165.034 172.282 1.00 89.73  ? 21  LYS A O    1 
ATOM   149  C  CB   . LYS A 1 10  ? 133.939 163.491 170.415 1.00 89.34  ? 21  LYS A CB   1 
ATOM   150  C  CG   . LYS A 1 10  ? 133.013 164.145 171.444 1.00 89.81  ? 21  LYS A CG   1 
ATOM   151  C  CD   . LYS A 1 10  ? 132.889 165.653 171.254 1.00 91.10  ? 21  LYS A CD   1 
ATOM   152  C  CE   . LYS A 1 10  ? 131.529 166.172 171.685 1.00 89.42  ? 21  LYS A CE   1 
ATOM   153  N  NZ   . LYS A 1 10  ? 131.472 167.660 171.628 1.00 89.80  ? 21  LYS A NZ   1 
ATOM   154  H  H    . LYS A 1 10  ? 135.594 163.026 168.661 1.00 88.89  ? 21  LYS A H    1 
ATOM   155  H  HA   . LYS A 1 10  ? 135.072 165.172 170.055 1.00 90.17  ? 21  LYS A HA   1 
ATOM   156  H  HB2  . LYS A 1 10  ? 133.463 163.454 169.570 1.00 89.81  ? 21  LYS A HB2  1 
ATOM   157  H  HB3  . LYS A 1 10  ? 134.134 162.592 170.722 1.00 89.67  ? 21  LYS A HB3  1 
ATOM   158  H  HG2  . LYS A 1 10  ? 132.127 163.759 171.362 1.00 89.82  ? 21  LYS A HG2  1 
ATOM   159  H  HG3  . LYS A 1 10  ? 133.365 163.983 172.333 1.00 89.83  ? 21  LYS A HG3  1 
ATOM   160  H  HD2  . LYS A 1 10  ? 133.566 166.098 171.787 1.00 90.07  ? 21  LYS A HD2  1 
ATOM   161  H  HD3  . LYS A 1 10  ? 133.007 165.868 170.316 1.00 90.28  ? 21  LYS A HD3  1 
ATOM   162  H  HE2  . LYS A 1 10  ? 130.848 165.819 171.092 1.00 89.82  ? 21  LYS A HE2  1 
ATOM   163  H  HE3  . LYS A 1 10  ? 131.356 165.896 172.599 1.00 89.86  ? 21  LYS A HE3  1 
ATOM   164  H  HZ1  . LYS A 1 10  ? 130.641 167.939 171.782 1.00 89.64  ? 21  LYS A HZ1  1 
ATOM   165  H  HZ2  . LYS A 1 10  ? 132.012 168.008 172.244 1.00 89.94  ? 21  LYS A HZ2  1 
ATOM   166  H  HZ3  . LYS A 1 10  ? 131.729 167.944 170.825 1.00 90.26  ? 21  LYS A HZ3  1 
ATOM   167  N  N    . LYS A 1 11  ? 136.892 163.033 171.574 1.00 82.73  ? 22  LYS A N    1 
ATOM   168  C  CA   . LYS A 1 11  ? 137.686 162.824 172.779 1.00 82.07  ? 22  LYS A CA   1 
ATOM   169  C  C    . LYS A 1 11  ? 138.875 163.775 172.841 1.00 83.63  ? 22  LYS A C    1 
ATOM   170  O  O    . LYS A 1 11  ? 139.204 164.294 173.915 1.00 82.26  ? 22  LYS A O    1 
ATOM   171  C  CB   . LYS A 1 11  ? 138.162 161.373 172.843 1.00 79.01  ? 22  LYS A CB   1 
ATOM   172  H  H    . LYS A 1 11  ? 136.956 162.406 170.989 1.00 83.13  ? 22  LYS A H    1 
ATOM   173  H  HA   . LYS A 1 11  ? 137.129 162.991 173.556 1.00 83.08  ? 22  LYS A HA   1 
ATOM   174  N  N    . VAL A 1 12  ? 139.532 164.020 171.708 1.00 83.41  ? 23  VAL A N    1 
ATOM   175  C  CA   . VAL A 1 12  ? 140.769 164.792 171.699 1.00 84.12  ? 23  VAL A CA   1 
ATOM   176  C  C    . VAL A 1 12  ? 140.465 166.280 171.619 1.00 84.78  ? 23  VAL A C    1 
ATOM   177  O  O    . VAL A 1 12  ? 140.786 167.042 172.539 1.00 82.86  ? 23  VAL A O    1 
ATOM   178  C  CB   . VAL A 1 12  ? 141.678 164.373 170.530 1.00 80.79  ? 23  VAL A CB   1 
ATOM   179  C  CG1  . VAL A 1 12  ? 142.911 165.267 170.484 1.00 83.20  ? 23  VAL A CG1  1 
ATOM   180  C  CG2  . VAL A 1 12  ? 142.071 162.910 170.655 1.00 78.00  ? 23  VAL A CG2  1 
ATOM   181  H  H    . VAL A 1 12  ? 139.281 163.748 170.932 1.00 81.80  ? 23  VAL A H    1 
ATOM   182  H  HA   . VAL A 1 12  ? 141.251 164.629 172.525 1.00 81.73  ? 23  VAL A HA   1 
ATOM   183  H  HB   . VAL A 1 12  ? 141.193 164.486 169.698 1.00 81.21  ? 23  VAL A HB   1 
ATOM   184  H  HG11 . VAL A 1 12  ? 143.596 164.837 169.952 1.00 81.44  ? 23  VAL A HG11 1 
ATOM   185  H  HG12 . VAL A 1 12  ? 142.674 166.120 170.088 1.00 82.06  ? 23  VAL A HG12 1 
ATOM   186  H  HG13 . VAL A 1 12  ? 143.235 165.399 171.389 1.00 81.86  ? 23  VAL A HG13 1 
ATOM   187  H  HG21 . VAL A 1 12  ? 142.645 162.673 169.910 1.00 80.76  ? 23  VAL A HG21 1 
ATOM   188  H  HG22 . VAL A 1 12  ? 142.546 162.784 171.492 1.00 81.02  ? 23  VAL A HG22 1 
ATOM   189  H  HG23 . VAL A 1 12  ? 141.270 162.363 170.642 1.00 81.02  ? 23  VAL A HG23 1 
ATOM   190  N  N    . PHE A 1 13  ? 139.847 166.703 170.522 1.00 80.36  ? 24  PHE A N    1 
ATOM   191  C  CA   . PHE A 1 13  ? 139.643 168.116 170.240 1.00 77.15  ? 24  PHE A CA   1 
ATOM   192  C  C    . PHE A 1 13  ? 138.310 168.636 170.755 1.00 79.42  ? 24  PHE A C    1 
ATOM   193  O  O    . PHE A 1 13  ? 138.000 169.814 170.545 1.00 79.17  ? 24  PHE A O    1 
ATOM   194  C  CB   . PHE A 1 13  ? 139.738 168.365 168.731 1.00 76.06  ? 24  PHE A CB   1 
ATOM   195  C  CG   . PHE A 1 13  ? 141.009 167.858 168.110 1.00 75.34  ? 24  PHE A CG   1 
ATOM   196  C  CD1  . PHE A 1 13  ? 141.137 166.526 167.749 1.00 78.97  ? 24  PHE A CD1  1 
ATOM   197  C  CD2  . PHE A 1 13  ? 142.074 168.711 167.882 1.00 76.46  ? 24  PHE A CD2  1 
ATOM   198  C  CE1  . PHE A 1 13  ? 142.303 166.056 167.178 1.00 78.94  ? 24  PHE A CE1  1 
ATOM   199  C  CE2  . PHE A 1 13  ? 143.243 168.246 167.311 1.00 79.75  ? 24  PHE A CE2  1 
ATOM   200  C  CZ   . PHE A 1 13  ? 143.357 166.917 166.958 1.00 78.09  ? 24  PHE A CZ   1 
ATOM   201  H  H    . PHE A 1 13  ? 139.532 166.180 169.916 1.00 78.92  ? 24  PHE A H    1 
ATOM   202  H  HA   . PHE A 1 13  ? 140.346 168.626 170.671 1.00 78.17  ? 24  PHE A HA   1 
ATOM   203  H  HB2  . PHE A 1 13  ? 138.995 167.920 168.294 1.00 78.25  ? 24  PHE A HB2  1 
ATOM   204  H  HB3  . PHE A 1 13  ? 139.690 169.321 168.570 1.00 78.30  ? 24  PHE A HB3  1 
ATOM   205  H  HD1  . PHE A 1 13  ? 140.429 165.940 167.896 1.00 78.56  ? 24  PHE A HD1  1 
ATOM   206  H  HD2  . PHE A 1 13  ? 142.004 169.608 168.118 1.00 77.99  ? 24  PHE A HD2  1 
ATOM   207  H  HE1  . PHE A 1 13  ? 142.378 165.159 166.941 1.00 78.45  ? 24  PHE A HE1  1 
ATOM   208  H  HE2  . PHE A 1 13  ? 143.953 168.828 167.163 1.00 78.57  ? 24  PHE A HE2  1 
ATOM   209  H  HZ   . PHE A 1 13  ? 144.143 166.603 166.573 1.00 77.94  ? 24  PHE A HZ   1 
ATOM   210  N  N    . GLY A 1 14  ? 137.517 167.799 171.418 1.00 86.72  ? 25  GLY A N    1 
ATOM   211  C  CA   . GLY A 1 14  ? 136.213 168.234 171.874 1.00 87.11  ? 25  GLY A CA   1 
ATOM   212  C  C    . GLY A 1 14  ? 135.286 168.649 170.758 1.00 86.29  ? 25  GLY A C    1 
ATOM   213  O  O    . GLY A 1 14  ? 134.316 169.371 171.003 1.00 90.73  ? 25  GLY A O    1 
ATOM   214  H  H    . GLY A 1 14  ? 137.711 166.984 171.614 1.00 86.44  ? 25  GLY A H    1 
ATOM   215  H  HA2  . GLY A 1 14  ? 135.790 167.515 172.368 1.00 86.82  ? 25  GLY A HA2  1 
ATOM   216  H  HA3  . GLY A 1 14  ? 136.322 168.990 172.473 1.00 87.03  ? 25  GLY A HA3  1 
ATOM   217  N  N    . PHE A 1 15  ? 135.558 168.211 169.531 1.00 72.49  ? 26  PHE A N    1 
ATOM   218  C  CA   . PHE A 1 15  ? 134.759 168.585 168.370 1.00 74.60  ? 26  PHE A CA   1 
ATOM   219  C  C    . PHE A 1 15  ? 133.717 167.499 168.132 1.00 79.30  ? 26  PHE A C    1 
ATOM   220  O  O    . PHE A 1 15  ? 134.056 166.375 167.750 1.00 78.40  ? 26  PHE A O    1 
ATOM   221  C  CB   . PHE A 1 15  ? 135.649 168.768 167.142 1.00 75.22  ? 26  PHE A CB   1 
ATOM   222  C  CG   . PHE A 1 15  ? 136.245 170.148 167.010 1.00 77.73  ? 26  PHE A CG   1 
ATOM   223  C  CD1  . PHE A 1 15  ? 136.208 171.053 168.060 1.00 76.85  ? 26  PHE A CD1  1 
ATOM   224  C  CD2  . PHE A 1 15  ? 136.843 170.537 165.823 1.00 77.69  ? 26  PHE A CD2  1 
ATOM   225  C  CE1  . PHE A 1 15  ? 136.757 172.313 167.926 1.00 79.67  ? 26  PHE A CE1  1 
ATOM   226  C  CE2  . PHE A 1 15  ? 137.392 171.796 165.686 1.00 79.93  ? 26  PHE A CE2  1 
ATOM   227  C  CZ   . PHE A 1 15  ? 137.349 172.684 166.738 1.00 82.12  ? 26  PHE A CZ   1 
ATOM   228  H  H    . PHE A 1 15  ? 136.214 167.688 169.343 1.00 78.09  ? 26  PHE A H    1 
ATOM   229  H  HA   . PHE A 1 15  ? 134.282 169.409 168.549 1.00 78.05  ? 26  PHE A HA   1 
ATOM   230  H  HB2  . PHE A 1 15  ? 136.383 168.139 167.198 1.00 78.02  ? 26  PHE A HB2  1 
ATOM   231  H  HB3  . PHE A 1 15  ? 135.125 168.593 166.346 1.00 77.77  ? 26  PHE A HB3  1 
ATOM   232  H  HD1  . PHE A 1 15  ? 135.812 170.811 168.866 1.00 77.72  ? 26  PHE A HD1  1 
ATOM   233  H  HD2  . PHE A 1 15  ? 136.875 169.942 165.109 1.00 77.74  ? 26  PHE A HD2  1 
ATOM   234  H  HE1  . PHE A 1 15  ? 136.728 172.911 168.638 1.00 78.26  ? 26  PHE A HE1  1 
ATOM   235  H  HE2  . PHE A 1 15  ? 137.790 172.045 164.883 1.00 78.03  ? 26  PHE A HE2  1 
ATOM   236  H  HZ   . PHE A 1 15  ? 137.719 173.533 166.647 1.00 78.63  ? 26  PHE A HZ   1 
ATOM   237  N  N    . ASP A 1 16  ? 132.446 167.834 168.364 1.00 100.07 ? 27  ASP A N    1 
ATOM   238  C  CA   . ASP A 1 16  ? 131.377 166.875 168.113 1.00 97.58  ? 27  ASP A CA   1 
ATOM   239  C  C    . ASP A 1 16  ? 131.307 166.510 166.636 1.00 92.41  ? 27  ASP A C    1 
ATOM   240  O  O    . ASP A 1 16  ? 131.125 165.338 166.285 1.00 84.51  ? 27  ASP A O    1 
ATOM   241  C  CB   . ASP A 1 16  ? 130.040 167.445 168.587 1.00 99.53  ? 27  ASP A CB   1 
ATOM   242  C  CG   . ASP A 1 16  ? 129.031 166.365 168.925 1.00 100.75 ? 27  ASP A CG   1 
ATOM   243  O  OD1  . ASP A 1 16  ? 129.296 165.183 168.623 1.00 102.52 ? 27  ASP A OD1  1 
ATOM   244  O  OD2  . ASP A 1 16  ? 127.970 166.699 169.495 1.00 99.31  ? 27  ASP A OD2  1 
ATOM   245  H  H    . ASP A 1 16  ? 132.183 168.597 168.662 1.00 96.35  ? 27  ASP A H    1 
ATOM   246  H  HA   . ASP A 1 16  ? 131.554 166.064 168.615 1.00 95.99  ? 27  ASP A HA   1 
ATOM   247  H  HB2  . ASP A 1 16  ? 130.187 167.979 169.384 1.00 96.44  ? 27  ASP A HB2  1 
ATOM   248  H  HB3  . ASP A 1 16  ? 129.665 167.998 167.884 1.00 96.74  ? 27  ASP A HB3  1 
ATOM   249  N  N    . SER A 1 17  ? 131.454 167.499 165.757 1.00 95.32  ? 28  SER A N    1 
ATOM   250  C  CA   . SER A 1 17  ? 131.388 167.277 164.322 1.00 96.31  ? 28  SER A CA   1 
ATOM   251  C  C    . SER A 1 17  ? 132.417 168.156 163.627 1.00 94.98  ? 28  SER A C    1 
ATOM   252  O  O    . SER A 1 17  ? 132.850 169.181 164.158 1.00 98.02  ? 28  SER A O    1 
ATOM   253  C  CB   . SER A 1 17  ? 129.985 167.565 163.771 1.00 94.84  ? 28  SER A CB   1 
ATOM   254  O  OG   . SER A 1 17  ? 129.038 166.642 164.280 1.00 92.72  ? 28  SER A OG   1 
ATOM   255  H  H    . SER A 1 17  ? 131.596 168.319 165.975 1.00 94.53  ? 28  SER A H    1 
ATOM   256  H  HA   . SER A 1 17  ? 131.608 166.355 164.136 1.00 94.24  ? 28  SER A HA   1 
ATOM   257  H  HB2  . SER A 1 17  ? 129.722 168.462 164.032 1.00 94.44  ? 28  SER A HB2  1 
ATOM   258  H  HB3  . SER A 1 17  ? 130.006 167.494 162.804 1.00 94.35  ? 28  SER A HB3  1 
ATOM   259  H  HG   . SER A 1 17  ? 129.271 165.857 164.089 1.00 94.14  ? 28  SER A HG   1 
ATOM   260  N  N    . PHE A 1 18  ? 132.806 167.736 162.426 1.00 75.44  ? 29  PHE A N    1 
ATOM   261  C  CA   . PHE A 1 18  ? 133.789 168.485 161.658 1.00 73.44  ? 29  PHE A CA   1 
ATOM   262  C  C    . PHE A 1 18  ? 133.217 169.831 161.234 1.00 73.06  ? 29  PHE A C    1 
ATOM   263  O  O    . PHE A 1 18  ? 132.045 169.938 160.862 1.00 73.49  ? 29  PHE A O    1 
ATOM   264  C  CB   . PHE A 1 18  ? 134.225 167.695 160.425 1.00 74.44  ? 29  PHE A CB   1 
ATOM   265  C  CG   . PHE A 1 18  ? 134.997 166.445 160.741 1.00 78.21  ? 29  PHE A CG   1 
ATOM   266  C  CD1  . PHE A 1 18  ? 134.382 165.364 161.350 1.00 80.36  ? 29  PHE A CD1  1 
ATOM   267  C  CD2  . PHE A 1 18  ? 136.343 166.354 160.431 1.00 77.99  ? 29  PHE A CD2  1 
ATOM   268  C  CE1  . PHE A 1 18  ? 135.092 164.215 161.636 1.00 81.32  ? 29  PHE A CE1  1 
ATOM   269  C  CE2  . PHE A 1 18  ? 137.058 165.208 160.717 1.00 75.83  ? 29  PHE A CE2  1 
ATOM   270  C  CZ   . PHE A 1 18  ? 136.432 164.138 161.321 1.00 77.11  ? 29  PHE A CZ   1 
ATOM   271  H  H    . PHE A 1 18  ? 132.511 167.030 162.036 1.00 77.55  ? 29  PHE A H    1 
ATOM   272  H  HA   . PHE A 1 18  ? 134.571 168.647 162.209 1.00 77.26  ? 29  PHE A HA   1 
ATOM   273  H  HB2  . PHE A 1 18  ? 133.436 167.437 159.924 1.00 76.78  ? 29  PHE A HB2  1 
ATOM   274  H  HB3  . PHE A 1 18  ? 134.791 168.261 159.877 1.00 76.92  ? 29  PHE A HB3  1 
ATOM   275  H  HD1  . PHE A 1 18  ? 133.478 165.411 161.563 1.00 78.08  ? 29  PHE A HD1  1 
ATOM   276  H  HD2  . PHE A 1 18  ? 136.770 167.072 160.023 1.00 76.91  ? 29  PHE A HD2  1 
ATOM   277  H  HE1  . PHE A 1 18  ? 134.668 163.496 162.045 1.00 78.39  ? 29  PHE A HE1  1 
ATOM   278  H  HE2  . PHE A 1 18  ? 137.962 165.158 160.503 1.00 76.46  ? 29  PHE A HE2  1 
ATOM   279  H  HZ   . PHE A 1 18  ? 136.913 163.366 161.516 1.00 76.83  ? 29  PHE A HZ   1 
ATOM   280  N  N    . LYS A 1 19  ? 134.056 170.866 161.291 1.00 78.84  ? 30  LYS A N    1 
ATOM   281  C  CA   . LYS A 1 19  ? 133.606 172.197 160.900 1.00 81.80  ? 30  LYS A CA   1 
ATOM   282  C  C    . LYS A 1 19  ? 133.223 172.252 159.427 1.00 84.57  ? 30  LYS A C    1 
ATOM   283  O  O    . LYS A 1 19  ? 132.362 173.052 159.041 1.00 87.45  ? 30  LYS A O    1 
ATOM   284  C  CB   . LYS A 1 19  ? 134.692 173.230 161.204 1.00 80.72  ? 30  LYS A CB   1 
ATOM   285  C  CG   . LYS A 1 19  ? 135.009 173.367 162.684 1.00 84.84  ? 30  LYS A CG   1 
ATOM   286  C  CD   . LYS A 1 19  ? 135.999 174.490 162.947 1.00 86.80  ? 30  LYS A CD   1 
ATOM   287  C  CE   . LYS A 1 19  ? 137.403 174.117 162.504 1.00 86.26  ? 30  LYS A CE   1 
ATOM   288  N  NZ   . LYS A 1 19  ? 138.394 175.166 162.871 1.00 87.81  ? 30  LYS A NZ   1 
ATOM   289  H  H    . LYS A 1 19  ? 134.874 170.825 161.552 1.00 82.68  ? 30  LYS A H    1 
ATOM   290  H  HA   . LYS A 1 19  ? 132.821 172.428 161.421 1.00 83.32  ? 30  LYS A HA   1 
ATOM   291  H  HB2  . LYS A 1 19  ? 135.508 172.968 160.749 1.00 82.73  ? 30  LYS A HB2  1 
ATOM   292  H  HB3  . LYS A 1 19  ? 134.399 174.096 160.882 1.00 83.01  ? 30  LYS A HB3  1 
ATOM   293  H  HG2  . LYS A 1 19  ? 134.192 173.564 163.169 1.00 83.89  ? 30  LYS A HG2  1 
ATOM   294  H  HG3  . LYS A 1 19  ? 135.398 172.539 163.005 1.00 83.54  ? 30  LYS A HG3  1 
ATOM   295  H  HD2  . LYS A 1 19  ? 135.726 175.280 162.454 1.00 83.99  ? 30  LYS A HD2  1 
ATOM   296  H  HD3  . LYS A 1 19  ? 136.021 174.680 163.898 1.00 84.02  ? 30  LYS A HD3  1 
ATOM   297  H  HE2  . LYS A 1 19  ? 137.664 173.289 162.937 1.00 83.63  ? 30  LYS A HE2  1 
ATOM   298  H  HE3  . LYS A 1 19  ? 137.418 174.010 161.540 1.00 83.86  ? 30  LYS A HE3  1 
ATOM   299  H  HZ1  . LYS A 1 19  ? 139.208 174.923 162.605 1.00 84.18  ? 30  LYS A HZ1  1 
ATOM   300  H  HZ2  . LYS A 1 19  ? 138.180 175.936 162.479 1.00 84.41  ? 30  LYS A HZ2  1 
ATOM   301  H  HZ3  . LYS A 1 19  ? 138.400 175.283 163.753 1.00 83.64  ? 30  LYS A HZ3  1 
ATOM   302  N  N    . THR A 1 20  ? 133.842 171.421 158.595 1.00 79.98  ? 31  THR A N    1 
ATOM   303  C  CA   . THR A 1 20  ? 133.585 171.407 157.164 1.00 75.69  ? 31  THR A CA   1 
ATOM   304  C  C    . THR A 1 20  ? 133.452 169.963 156.701 1.00 69.79  ? 31  THR A C    1 
ATOM   305  O  O    . THR A 1 20  ? 134.081 169.068 157.276 1.00 72.54  ? 31  THR A O    1 
ATOM   306  C  CB   . THR A 1 20  ? 134.719 172.102 156.391 1.00 79.61  ? 31  THR A CB   1 
ATOM   307  O  OG1  . THR A 1 20  ? 134.892 173.434 156.890 1.00 81.81  ? 31  THR A OG1  1 
ATOM   308  C  CG2  . THR A 1 20  ? 134.406 172.174 154.907 1.00 74.89  ? 31  THR A CG2  1 
ATOM   309  H  H    . THR A 1 20  ? 134.428 170.843 158.843 1.00 77.23  ? 31  THR A H    1 
ATOM   310  H  HA   . THR A 1 20  ? 132.761 171.882 156.987 1.00 76.49  ? 31  THR A HA   1 
ATOM   311  H  HB   . THR A 1 20  ? 135.543 171.603 156.507 1.00 77.12  ? 31  THR A HB   1 
ATOM   312  H  HG1  . THR A 1 20  ? 135.525 173.811 156.486 1.00 76.76  ? 31  THR A HG1  1 
ATOM   313  H  HG21 . THR A 1 20  ? 135.080 172.704 154.454 1.00 76.00  ? 31  THR A HG21 1 
ATOM   314  H  HG22 . THR A 1 20  ? 134.400 171.285 154.526 1.00 76.29  ? 31  THR A HG22 1 
ATOM   315  H  HG23 . THR A 1 20  ? 133.539 172.586 154.770 1.00 75.47  ? 31  THR A HG23 1 
ATOM   316  N  N    . PRO A 1 21  ? 132.634 169.700 155.674 1.00 64.92  ? 32  PRO A N    1 
ATOM   317  C  CA   . PRO A 1 21  ? 132.572 168.323 155.156 1.00 68.79  ? 32  PRO A CA   1 
ATOM   318  C  C    . PRO A 1 21  ? 133.801 167.939 154.353 1.00 72.33  ? 32  PRO A C    1 
ATOM   319  O  O    . PRO A 1 21  ? 134.251 166.787 154.425 1.00 66.28  ? 32  PRO A O    1 
ATOM   320  C  CB   . PRO A 1 21  ? 131.303 168.324 154.288 1.00 68.99  ? 32  PRO A CB   1 
ATOM   321  C  CG   . PRO A 1 21  ? 130.582 169.596 154.614 1.00 69.70  ? 32  PRO A CG   1 
ATOM   322  C  CD   . PRO A 1 21  ? 131.630 170.565 155.034 1.00 68.85  ? 32  PRO A CD   1 
ATOM   323  H  HA   . PRO A 1 21  ? 132.458 167.694 155.886 1.00 68.54  ? 32  PRO A HA   1 
ATOM   324  H  HB2  . PRO A 1 21  ? 131.551 168.304 153.350 1.00 68.97  ? 32  PRO A HB2  1 
ATOM   325  H  HB3  . PRO A 1 21  ? 130.755 167.555 154.512 1.00 69.04  ? 32  PRO A HB3  1 
ATOM   326  H  HG2  . PRO A 1 21  ? 130.119 169.918 153.824 1.00 68.77  ? 32  PRO A HG2  1 
ATOM   327  H  HG3  . PRO A 1 21  ? 129.955 169.438 155.336 1.00 69.57  ? 32  PRO A HG3  1 
ATOM   328  H  HD2  . PRO A 1 21  ? 132.006 171.010 154.260 1.00 68.98  ? 32  PRO A HD2  1 
ATOM   329  H  HD3  . PRO A 1 21  ? 131.258 171.198 155.667 1.00 69.69  ? 32  PRO A HD3  1 
ATOM   330  N  N    . LEU A 1 22  ? 134.353 168.873 153.577 1.00 79.21  ? 33  LEU A N    1 
ATOM   331  C  CA   . LEU A 1 22  ? 135.545 168.568 152.796 1.00 77.82  ? 33  LEU A CA   1 
ATOM   332  C  C    . LEU A 1 22  ? 136.719 168.226 153.703 1.00 74.01  ? 33  LEU A C    1 
ATOM   333  O  O    . LEU A 1 22  ? 137.506 167.325 153.397 1.00 77.60  ? 33  LEU A O    1 
ATOM   334  C  CB   . LEU A 1 22  ? 135.899 169.746 151.888 1.00 77.86  ? 33  LEU A CB   1 
ATOM   335  C  CG   . LEU A 1 22  ? 137.305 169.694 151.288 1.00 74.84  ? 33  LEU A CG   1 
ATOM   336  C  CD1  . LEU A 1 22  ? 137.485 168.400 150.509 1.00 74.27  ? 33  LEU A CD1  1 
ATOM   337  C  CD2  . LEU A 1 22  ? 137.564 170.897 150.407 1.00 71.91  ? 33  LEU A CD2  1 
ATOM   338  H  H    . LEU A 1 22  ? 134.053 169.671 153.477 1.00 74.83  ? 33  LEU A H    1 
ATOM   339  H  HA   . LEU A 1 22  ? 135.366 167.798 152.234 1.00 74.80  ? 33  LEU A HA   1 
ATOM   340  H  HB2  . LEU A 1 22  ? 135.267 169.769 151.152 1.00 75.11  ? 33  LEU A HB2  1 
ATOM   341  H  HB3  . LEU A 1 22  ? 135.830 170.565 152.403 1.00 74.63  ? 33  LEU A HB3  1 
ATOM   342  H  HG   . LEU A 1 22  ? 137.964 169.712 151.999 1.00 74.68  ? 33  LEU A HG   1 
ATOM   343  H  HD11 . LEU A 1 22  ? 138.010 168.576 149.714 1.00 74.43  ? 33  LEU A HD11 1 
ATOM   344  H  HD12 . LEU A 1 22  ? 137.940 167.755 151.071 1.00 74.85  ? 33  LEU A HD12 1 
ATOM   345  H  HD13 . LEU A 1 22  ? 136.612 168.062 150.255 1.00 74.37  ? 33  LEU A HD13 1 
ATOM   346  H  HD21 . LEU A 1 22  ? 138.358 170.737 149.875 1.00 74.89  ? 33  LEU A HD21 1 
ATOM   347  H  HD22 . LEU A 1 22  ? 136.798 171.038 149.828 1.00 74.20  ? 33  LEU A HD22 1 
ATOM   348  H  HD23 . LEU A 1 22  ? 137.697 171.668 150.978 1.00 73.90  ? 33  LEU A HD23 1 
ATOM   349  N  N    . GLN A 1 23  ? 136.867 168.943 154.819 1.00 75.40  ? 34  GLN A N    1 
ATOM   350  C  CA   . GLN A 1 23  ? 137.932 168.597 155.753 1.00 77.25  ? 34  GLN A CA   1 
ATOM   351  C  C    . GLN A 1 23  ? 137.673 167.243 156.398 1.00 78.41  ? 34  GLN A C    1 
ATOM   352  O  O    . GLN A 1 23  ? 138.621 166.517 156.714 1.00 80.49  ? 34  GLN A O    1 
ATOM   353  C  CB   . GLN A 1 23  ? 138.091 169.687 156.816 1.00 76.22  ? 34  GLN A CB   1 
ATOM   354  C  CG   . GLN A 1 23  ? 137.246 169.506 158.065 1.00 78.95  ? 34  GLN A CG   1 
ATOM   355  C  CD   . GLN A 1 23  ? 137.391 170.665 159.029 1.00 79.13  ? 34  GLN A CD   1 
ATOM   356  O  OE1  . GLN A 1 23  ? 138.030 171.670 158.717 1.00 76.30  ? 34  GLN A OE1  1 
ATOM   357  N  NE2  . GLN A 1 23  ? 136.805 170.528 160.211 1.00 78.99  ? 34  GLN A NE2  1 
ATOM   358  H  H    . GLN A 1 23  ? 136.381 169.614 155.051 1.00 77.13  ? 34  GLN A H    1 
ATOM   359  H  HA   . GLN A 1 23  ? 138.768 168.536 155.264 1.00 77.35  ? 34  GLN A HA   1 
ATOM   360  H  HB2  . GLN A 1 23  ? 139.019 169.714 157.095 1.00 77.42  ? 34  GLN A HB2  1 
ATOM   361  H  HB3  . GLN A 1 23  ? 137.847 170.538 156.421 1.00 76.83  ? 34  GLN A HB3  1 
ATOM   362  H  HG2  . GLN A 1 23  ? 136.314 169.439 157.811 1.00 78.29  ? 34  GLN A HG2  1 
ATOM   363  H  HG3  . GLN A 1 23  ? 137.525 168.703 158.533 1.00 76.97  ? 34  GLN A HG3  1 
ATOM   364  H  HE21 . GLN A 1 23  ? 136.368 169.810 160.394 1.00 77.74  ? 34  GLN A HE21 1 
ATOM   365  H  HE22 . GLN A 1 23  ? 136.860 171.158 160.794 1.00 77.61  ? 34  GLN A HE22 1 
ATOM   366  N  N    . GLU A 1 24  ? 136.404 166.877 156.591 1.00 84.42  ? 35  GLU A N    1 
ATOM   367  C  CA   . GLU A 1 24  ? 136.097 165.530 157.060 1.00 83.79  ? 35  GLU A CA   1 
ATOM   368  C  C    . GLU A 1 24  ? 136.560 164.489 156.050 1.00 78.11  ? 35  GLU A C    1 
ATOM   369  O  O    . GLU A 1 24  ? 137.165 163.475 156.421 1.00 75.60  ? 35  GLU A O    1 
ATOM   370  C  CB   . GLU A 1 24  ? 134.598 165.394 157.324 1.00 87.96  ? 35  GLU A CB   1 
ATOM   371  C  CG   . GLU A 1 24  ? 134.164 163.995 157.733 1.00 87.52  ? 35  GLU A CG   1 
ATOM   372  C  CD   . GLU A 1 24  ? 132.749 163.957 158.278 1.00 86.59  ? 35  GLU A CD   1 
ATOM   373  O  OE1  . GLU A 1 24  ? 132.192 165.036 158.573 1.00 84.66  ? 35  GLU A OE1  1 
ATOM   374  O  OE2  . GLU A 1 24  ? 132.193 162.847 158.412 1.00 87.51  ? 35  GLU A OE2  1 
ATOM   375  H  H    . GLU A 1 24  ? 135.718 167.380 156.462 1.00 82.45  ? 35  GLU A H    1 
ATOM   376  H  HA   . GLU A 1 24  ? 136.567 165.368 157.892 1.00 82.75  ? 35  GLU A HA   1 
ATOM   377  H  HB2  . GLU A 1 24  ? 134.352 166.003 158.038 1.00 83.04  ? 35  GLU A HB2  1 
ATOM   378  H  HB3  . GLU A 1 24  ? 134.115 165.627 156.516 1.00 82.61  ? 35  GLU A HB3  1 
ATOM   379  H  HG2  . GLU A 1 24  ? 134.201 163.412 156.959 1.00 83.59  ? 35  GLU A HG2  1 
ATOM   380  H  HG3  . GLU A 1 24  ? 134.761 163.668 158.424 1.00 82.96  ? 35  GLU A HG3  1 
ATOM   381  N  N    . SER A 1 25  ? 136.297 164.728 154.764 1.00 79.90  ? 36  SER A N    1 
ATOM   382  C  CA   . SER A 1 25  ? 136.765 163.806 153.734 1.00 88.62  ? 36  SER A CA   1 
ATOM   383  C  C    . SER A 1 25  ? 138.287 163.743 153.708 1.00 83.91  ? 36  SER A C    1 
ATOM   384  O  O    . SER A 1 25  ? 138.872 162.672 153.508 1.00 78.03  ? 36  SER A O    1 
ATOM   385  C  CB   . SER A 1 25  ? 136.220 164.226 152.369 1.00 85.34  ? 36  SER A CB   1 
ATOM   386  O  OG   . SER A 1 25  ? 137.054 165.198 151.764 1.00 82.83  ? 36  SER A OG   1 
ATOM   387  H  H    . SER A 1 25  ? 135.857 165.406 154.468 1.00 81.02  ? 36  SER A H    1 
ATOM   388  H  HA   . SER A 1 25  ? 136.431 162.917 153.931 1.00 83.28  ? 36  SER A HA   1 
ATOM   389  H  HB2  . SER A 1 25  ? 136.176 163.446 151.794 1.00 82.67  ? 36  SER A HB2  1 
ATOM   390  H  HB3  . SER A 1 25  ? 135.333 164.601 152.486 1.00 81.92  ? 36  SER A HB3  1 
ATOM   391  H  HG   . SER A 1 25  ? 137.103 165.880 152.253 1.00 82.21  ? 36  SER A HG   1 
ATOM   392  N  N    . ALA A 1 26  ? 138.945 164.888 153.897 1.00 73.87  ? 37  ALA A N    1 
ATOM   393  C  CA   . ALA A 1 26  ? 140.404 164.910 153.922 1.00 67.80  ? 37  ALA A CA   1 
ATOM   394  C  C    . ALA A 1 26  ? 140.946 164.105 155.094 1.00 65.21  ? 37  ALA A C    1 
ATOM   395  O  O    . ALA A 1 26  ? 141.930 163.369 154.952 1.00 69.80  ? 37  ALA A O    1 
ATOM   396  C  CB   . ALA A 1 26  ? 140.905 166.352 153.983 1.00 71.13  ? 37  ALA A CB   1 
ATOM   397  H  H    . ALA A 1 26  ? 138.574 165.655 154.012 1.00 72.11  ? 37  ALA A H    1 
ATOM   398  H  HA   . ALA A 1 26  ? 140.737 164.506 153.111 1.00 70.01  ? 37  ALA A HA   1 
ATOM   399  H  HB1  . ALA A 1 26  ? 141.874 166.348 154.033 1.00 70.64  ? 37  ALA A HB1  1 
ATOM   400  H  HB2  . ALA A 1 26  ? 140.616 166.821 153.185 1.00 70.83  ? 37  ALA A HB2  1 
ATOM   401  H  HB3  . ALA A 1 26  ? 140.534 166.779 154.770 1.00 70.25  ? 37  ALA A HB3  1 
ATOM   402  N  N    . THR A 1 27  ? 140.324 164.240 156.265 1.00 75.31  ? 38  THR A N    1 
ATOM   403  C  CA   . THR A 1 27  ? 140.739 163.445 157.414 1.00 81.23  ? 38  THR A CA   1 
ATOM   404  C  C    . THR A 1 27  ? 140.531 161.960 157.150 1.00 77.81  ? 38  THR A C    1 
ATOM   405  O  O    . THR A 1 27  ? 141.374 161.133 157.515 1.00 79.66  ? 38  THR A O    1 
ATOM   406  C  CB   . THR A 1 27  ? 139.970 163.881 158.661 1.00 90.13  ? 38  THR A CB   1 
ATOM   407  O  OG1  . THR A 1 27  ? 139.981 165.311 158.759 1.00 88.04  ? 38  THR A OG1  1 
ATOM   408  C  CG2  . THR A 1 27  ? 140.603 163.290 159.910 1.00 86.55  ? 38  THR A CG2  1 
ATOM   409  H  H    . THR A 1 27  ? 139.669 164.776 156.416 1.00 80.93  ? 38  THR A H    1 
ATOM   410  H  HA   . THR A 1 27  ? 141.684 163.593 157.576 1.00 81.14  ? 38  THR A HA   1 
ATOM   411  H  HB   . THR A 1 27  ? 139.054 163.568 158.603 1.00 82.56  ? 38  THR A HB   1 
ATOM   412  H  HG1  . THR A 1 27  ? 139.547 165.648 158.124 1.00 82.13  ? 38  THR A HG1  1 
ATOM   413  H  HG21 . THR A 1 27  ? 140.299 163.775 160.692 1.00 81.74  ? 38  THR A HG21 1 
ATOM   414  H  HG22 . THR A 1 27  ? 140.357 162.356 159.999 1.00 82.06  ? 38  THR A HG22 1 
ATOM   415  H  HG23 . THR A 1 27  ? 141.569 163.359 159.855 1.00 82.12  ? 38  THR A HG23 1 
ATOM   416  N  N    . MET A 1 28  ? 139.409 161.603 156.519 1.00 76.35  ? 39  MET A N    1 
ATOM   417  C  CA   . MET A 1 28  ? 139.182 160.208 156.150 1.00 80.77  ? 39  MET A CA   1 
ATOM   418  C  C    . MET A 1 28  ? 140.291 159.704 155.236 1.00 81.25  ? 39  MET A C    1 
ATOM   419  O  O    . MET A 1 28  ? 140.825 158.606 155.429 1.00 82.04  ? 39  MET A O    1 
ATOM   420  C  CB   . MET A 1 28  ? 137.824 160.057 155.461 1.00 85.68  ? 39  MET A CB   1 
ATOM   421  C  CG   . MET A 1 28  ? 136.615 160.347 156.332 1.00 84.77  ? 39  MET A CG   1 
ATOM   422  S  SD   . MET A 1 28  ? 136.484 159.237 157.742 1.00 95.52  ? 39  MET A SD   1 
ATOM   423  C  CE   . MET A 1 28  ? 137.089 160.301 159.043 1.00 83.91  ? 39  MET A CE   1 
ATOM   424  H  H    . MET A 1 28  ? 138.776 162.141 156.296 1.00 81.86  ? 39  MET A H    1 
ATOM   425  H  HA   . MET A 1 28  ? 139.172 159.670 156.956 1.00 82.51  ? 39  MET A HA   1 
ATOM   426  H  HB2  . MET A 1 28  ? 137.792 160.664 154.706 1.00 83.33  ? 39  MET A HB2  1 
ATOM   427  H  HB3  . MET A 1 28  ? 137.740 159.143 155.146 1.00 83.09  ? 39  MET A HB3  1 
ATOM   428  H  HG2  . MET A 1 28  ? 136.683 161.249 156.678 1.00 82.54  ? 39  MET A HG2  1 
ATOM   429  H  HG3  . MET A 1 28  ? 135.809 160.256 155.799 1.00 82.87  ? 39  MET A HG3  1 
ATOM   430  H  HE1  . MET A 1 28  ? 137.015 159.832 159.886 1.00 83.12  ? 39  MET A HE1  1 
ATOM   431  H  HE2  . MET A 1 28  ? 138.015 160.525 158.864 1.00 82.57  ? 39  MET A HE2  1 
ATOM   432  H  HE3  . MET A 1 28  ? 136.549 161.107 159.064 1.00 82.42  ? 39  MET A HE3  1 
ATOM   433  N  N    . ALA A 1 29  ? 140.649 160.500 154.228 1.00 65.80  ? 40  ALA A N    1 
ATOM   434  C  CA   . ALA A 1 29  ? 141.686 160.082 153.292 1.00 63.36  ? 40  ALA A CA   1 
ATOM   435  C  C    . ALA A 1 29  ? 143.025 159.913 153.995 1.00 59.81  ? 40  ALA A C    1 
ATOM   436  O  O    . ALA A 1 29  ? 143.747 158.940 153.745 1.00 57.73  ? 40  ALA A O    1 
ATOM   437  C  CB   . ALA A 1 29  ? 141.803 161.094 152.153 1.00 61.85  ? 40  ALA A CB   1 
ATOM   438  H  H    . ALA A 1 29  ? 140.311 161.274 154.067 1.00 64.31  ? 40  ALA A H    1 
ATOM   439  H  HA   . ALA A 1 29  ? 141.439 159.226 152.907 1.00 62.71  ? 40  ALA A HA   1 
ATOM   440  H  HB1  . ALA A 1 29  ? 142.486 160.794 151.533 1.00 62.58  ? 40  ALA A HB1  1 
ATOM   441  H  HB2  . ALA A 1 29  ? 140.948 161.159 151.699 1.00 62.05  ? 40  ALA A HB2  1 
ATOM   442  H  HB3  . ALA A 1 29  ? 142.047 161.956 152.525 1.00 63.51  ? 40  ALA A HB3  1 
ATOM   443  N  N    . VAL A 1 30  ? 143.376 160.849 154.877 1.00 45.55  ? 41  VAL A N    1 
ATOM   444  C  CA   . VAL A 1 30  ? 144.664 160.771 155.558 1.00 47.25  ? 41  VAL A CA   1 
ATOM   445  C  C    . VAL A 1 30  ? 144.710 159.552 156.471 1.00 51.44  ? 41  VAL A C    1 
ATOM   446  O  O    . VAL A 1 30  ? 145.675 158.780 156.450 1.00 61.96  ? 41  VAL A O    1 
ATOM   447  C  CB   . VAL A 1 30  ? 144.947 162.068 156.336 1.00 45.91  ? 41  VAL A CB   1 
ATOM   448  C  CG1  . VAL A 1 30  ? 146.218 161.922 157.158 1.00 51.19  ? 41  VAL A CG1  1 
ATOM   449  C  CG2  . VAL A 1 30  ? 145.074 163.242 155.384 1.00 46.46  ? 41  VAL A CG2  1 
ATOM   450  H  H    . VAL A 1 30  ? 142.894 161.527 155.095 1.00 54.81  ? 41  VAL A H    1 
ATOM   451  H  HA   . VAL A 1 30  ? 145.363 160.667 154.892 1.00 53.30  ? 41  VAL A HA   1 
ATOM   452  H  HB   . VAL A 1 30  ? 144.211 162.246 156.941 1.00 53.10  ? 41  VAL A HB   1 
ATOM   453  H  HG11 . VAL A 1 30  ? 146.433 162.779 157.557 1.00 51.87  ? 41  VAL A HG11 1 
ATOM   454  H  HG12 . VAL A 1 30  ? 146.081 161.263 157.853 1.00 52.51  ? 41  VAL A HG12 1 
ATOM   455  H  HG13 . VAL A 1 30  ? 146.939 161.640 156.574 1.00 52.63  ? 41  VAL A HG13 1 
ATOM   456  H  HG21 . VAL A 1 30  ? 145.144 164.060 155.901 1.00 52.04  ? 41  VAL A HG21 1 
ATOM   457  H  HG22 . VAL A 1 30  ? 145.871 163.123 154.844 1.00 52.16  ? 41  VAL A HG22 1 
ATOM   458  H  HG23 . VAL A 1 30  ? 144.291 163.277 154.815 1.00 53.07  ? 41  VAL A HG23 1 
ATOM   459  N  N    . VAL A 1 31  ? 143.670 159.356 157.286 1.00 59.34  ? 42  VAL A N    1 
ATOM   460  C  CA   . VAL A 1 31  ? 143.664 158.213 158.195 1.00 66.67  ? 42  VAL A CA   1 
ATOM   461  C  C    . VAL A 1 31  ? 143.646 156.911 157.410 1.00 63.63  ? 42  VAL A C    1 
ATOM   462  O  O    . VAL A 1 31  ? 144.164 155.889 157.876 1.00 70.01  ? 42  VAL A O    1 
ATOM   463  C  CB   . VAL A 1 31  ? 142.475 158.303 159.173 1.00 72.81  ? 42  VAL A CB   1 
ATOM   464  C  CG1  . VAL A 1 31  ? 141.156 158.102 158.446 1.00 70.01  ? 42  VAL A CG1  1 
ATOM   465  C  CG2  . VAL A 1 31  ? 142.633 157.284 160.293 1.00 72.13  ? 42  VAL A CG2  1 
ATOM   466  H  H    . VAL A 1 31  ? 142.972 159.857 157.329 1.00 67.07  ? 42  VAL A H    1 
ATOM   467  H  HA   . VAL A 1 31  ? 144.479 158.230 158.720 1.00 67.54  ? 42  VAL A HA   1 
ATOM   468  H  HB   . VAL A 1 31  ? 142.463 159.186 159.573 1.00 68.45  ? 42  VAL A HB   1 
ATOM   469  H  HG11 . VAL A 1 31  ? 140.429 158.233 159.075 1.00 68.24  ? 42  VAL A HG11 1 
ATOM   470  H  HG12 . VAL A 1 31  ? 141.093 158.752 157.732 1.00 69.30  ? 42  VAL A HG12 1 
ATOM   471  H  HG13 . VAL A 1 31  ? 141.118 157.203 158.083 1.00 68.37  ? 42  VAL A HG13 1 
ATOM   472  H  HG21 . VAL A 1 31  ? 141.914 157.406 160.933 1.00 68.22  ? 42  VAL A HG21 1 
ATOM   473  H  HG22 . VAL A 1 31  ? 142.594 156.391 159.918 1.00 68.71  ? 42  VAL A HG22 1 
ATOM   474  H  HG23 . VAL A 1 31  ? 143.489 157.424 160.728 1.00 68.31  ? 42  VAL A HG23 1 
ATOM   475  N  N    . LYS A 1 32  ? 143.056 156.920 156.214 1.00 57.82  ? 43  LYS A N    1 
ATOM   476  C  CA   . LYS A 1 32  ? 143.087 155.730 155.372 1.00 60.79  ? 43  LYS A CA   1 
ATOM   477  C  C    . LYS A 1 32  ? 144.519 155.349 155.023 1.00 53.34  ? 43  LYS A C    1 
ATOM   478  O  O    . LYS A 1 32  ? 144.887 154.169 155.068 1.00 54.61  ? 43  LYS A O    1 
ATOM   479  C  CB   . LYS A 1 32  ? 142.266 155.969 154.105 1.00 61.72  ? 43  LYS A CB   1 
ATOM   480  C  CG   . LYS A 1 32  ? 142.234 154.791 153.146 1.00 64.89  ? 43  LYS A CG   1 
ATOM   481  C  CD   . LYS A 1 32  ? 141.199 154.999 152.050 1.00 67.75  ? 43  LYS A CD   1 
ATOM   482  C  CE   . LYS A 1 32  ? 141.581 156.146 151.128 1.00 64.23  ? 43  LYS A CE   1 
ATOM   483  N  NZ   . LYS A 1 32  ? 140.695 156.226 149.934 1.00 64.98  ? 43  LYS A NZ   1 
ATOM   484  H  H    . LYS A 1 32  ? 142.638 157.590 155.873 1.00 61.40  ? 43  LYS A H    1 
ATOM   485  H  HA   . LYS A 1 32  ? 142.687 154.989 155.855 1.00 61.68  ? 43  LYS A HA   1 
ATOM   486  H  HB2  . LYS A 1 32  ? 141.351 156.166 154.360 1.00 61.44  ? 43  LYS A HB2  1 
ATOM   487  H  HB3  . LYS A 1 32  ? 142.643 156.726 153.630 1.00 61.18  ? 43  LYS A HB3  1 
ATOM   488  H  HG2  . LYS A 1 32  ? 143.104 154.694 152.727 1.00 61.60  ? 43  LYS A HG2  1 
ATOM   489  H  HG3  . LYS A 1 32  ? 142.004 153.985 153.634 1.00 61.14  ? 43  LYS A HG3  1 
ATOM   490  H  HD2  . LYS A 1 32  ? 141.130 154.191 151.518 1.00 61.97  ? 43  LYS A HD2  1 
ATOM   491  H  HD3  . LYS A 1 32  ? 140.342 155.208 152.455 1.00 61.78  ? 43  LYS A HD3  1 
ATOM   492  H  HE2  . LYS A 1 32  ? 141.508 156.982 151.613 1.00 61.35  ? 43  LYS A HE2  1 
ATOM   493  H  HE3  . LYS A 1 32  ? 142.492 156.017 150.820 1.00 60.94  ? 43  LYS A HE3  1 
ATOM   494  H  HZ1  . LYS A 1 32  ? 139.853 156.363 150.190 1.00 61.33  ? 43  LYS A HZ1  1 
ATOM   495  H  HZ2  . LYS A 1 32  ? 140.737 155.466 149.473 1.00 61.74  ? 43  LYS A HZ2  1 
ATOM   496  H  HZ3  . LYS A 1 32  ? 140.951 156.897 149.410 1.00 61.34  ? 43  LYS A HZ3  1 
ATOM   497  N  N    . GLY A 1 33  ? 145.342 156.334 154.672 1.00 36.48  ? 44  GLY A N    1 
ATOM   498  C  CA   . GLY A 1 33  ? 146.742 156.087 154.400 1.00 34.58  ? 44  GLY A CA   1 
ATOM   499  C  C    . GLY A 1 33  ? 147.027 155.402 153.086 1.00 42.36  ? 44  GLY A C    1 
ATOM   500  O  O    . GLY A 1 33  ? 148.179 155.041 152.831 1.00 43.45  ? 44  GLY A O    1 
ATOM   501  H  H    . GLY A 1 33  ? 145.107 157.157 154.586 1.00 45.46  ? 44  GLY A H    1 
ATOM   502  H  HA2  . GLY A 1 33  ? 147.216 156.933 154.403 1.00 42.09  ? 44  GLY A HA2  1 
ATOM   503  H  HA3  . GLY A 1 33  ? 147.108 155.536 155.110 1.00 43.14  ? 44  GLY A HA3  1 
ATOM   504  N  N    . ASN A 1 34  ? 146.015 155.212 152.239 1.00 60.94  ? 45  ASN A N    1 
ATOM   505  C  CA   . ASN A 1 34  ? 146.238 154.521 150.974 1.00 61.72  ? 45  ASN A CA   1 
ATOM   506  C  C    . ASN A 1 34  ? 146.984 155.401 149.981 1.00 57.71  ? 45  ASN A C    1 
ATOM   507  O  O    . ASN A 1 34  ? 147.658 154.884 149.082 1.00 68.16  ? 45  ASN A O    1 
ATOM   508  C  CB   . ASN A 1 34  ? 144.902 154.070 150.383 1.00 59.29  ? 45  ASN A CB   1 
ATOM   509  C  CG   . ASN A 1 34  ? 145.060 153.389 149.038 1.00 63.95  ? 45  ASN A CG   1 
ATOM   510  O  OD1  . ASN A 1 34  ? 144.555 153.869 148.023 1.00 57.80  ? 45  ASN A OD1  1 
ATOM   511  N  ND2  . ASN A 1 34  ? 145.765 152.264 149.023 1.00 67.42  ? 45  ASN A ND2  1 
ATOM   512  H  H    . ASN A 1 34  ? 145.205 155.469 152.370 1.00 60.47  ? 45  ASN A H    1 
ATOM   513  H  HA   . ASN A 1 34  ? 146.776 153.731 151.137 1.00 60.59  ? 45  ASN A HA   1 
ATOM   514  H  HB2  . ASN A 1 34  ? 144.483 153.441 150.991 1.00 60.05  ? 45  ASN A HB2  1 
ATOM   515  H  HB3  . ASN A 1 34  ? 144.333 154.845 150.261 1.00 60.08  ? 45  ASN A HB3  1 
ATOM   516  H  HD21 . ASN A 1 34  ? 146.104 151.958 149.752 1.00 61.50  ? 45  ASN A HD21 1 
ATOM   517  H  HD22 . ASN A 1 34  ? 145.883 151.840 148.284 1.00 61.62  ? 45  ASN A HD22 1 
ATOM   518  N  N    . LYS A 1 35  ? 146.883 156.720 150.124 1.00 40.48  ? 46  LYS A N    1 
ATOM   519  C  CA   . LYS A 1 35  ? 147.523 157.639 149.198 1.00 45.03  ? 46  LYS A CA   1 
ATOM   520  C  C    . LYS A 1 35  ? 147.833 158.937 149.925 1.00 44.62  ? 46  LYS A C    1 
ATOM   521  O  O    . LYS A 1 35  ? 147.209 159.270 150.936 1.00 46.06  ? 46  LYS A O    1 
ATOM   522  C  CB   . LYS A 1 35  ? 146.635 157.911 147.979 1.00 57.15  ? 46  LYS A CB   1 
ATOM   523  C  CG   . LYS A 1 35  ? 145.381 158.711 148.298 1.00 50.07  ? 46  LYS A CG   1 
ATOM   524  C  CD   . LYS A 1 35  ? 144.356 158.620 147.179 1.00 54.38  ? 46  LYS A CD   1 
ATOM   525  C  CE   . LYS A 1 35  ? 143.584 157.311 147.235 1.00 55.70  ? 46  LYS A CE   1 
ATOM   526  N  NZ   . LYS A 1 35  ? 142.411 157.312 146.318 1.00 59.71  ? 46  LYS A NZ   1 
ATOM   527  H  H    . LYS A 1 35  ? 146.446 157.107 150.755 1.00 50.73  ? 46  LYS A H    1 
ATOM   528  H  HA   . LYS A 1 35  ? 148.358 157.256 148.888 1.00 50.48  ? 46  LYS A HA   1 
ATOM   529  H  HB2  . LYS A 1 35  ? 147.147 158.411 147.324 1.00 52.52  ? 46  LYS A HB2  1 
ATOM   530  H  HB3  . LYS A 1 35  ? 146.357 157.062 147.600 1.00 52.46  ? 46  LYS A HB3  1 
ATOM   531  H  HG2  . LYS A 1 35  ? 144.978 158.364 149.110 1.00 50.89  ? 46  LYS A HG2  1 
ATOM   532  H  HG3  . LYS A 1 35  ? 145.618 159.644 148.415 1.00 50.21  ? 46  LYS A HG3  1 
ATOM   533  H  HD2  . LYS A 1 35  ? 143.723 159.350 147.265 1.00 50.81  ? 46  LYS A HD2  1 
ATOM   534  H  HD3  . LYS A 1 35  ? 144.810 158.669 146.324 1.00 51.47  ? 46  LYS A HD3  1 
ATOM   535  H  HE2  . LYS A 1 35  ? 144.170 156.584 146.973 1.00 51.46  ? 46  LYS A HE2  1 
ATOM   536  H  HE3  . LYS A 1 35  ? 143.260 157.170 148.138 1.00 51.05  ? 46  LYS A HE3  1 
ATOM   537  H  HZ1  . LYS A 1 35  ? 141.978 156.537 146.376 1.00 51.74  ? 46  LYS A HZ1  1 
ATOM   538  H  HZ2  . LYS A 1 35  ? 141.854 157.971 146.537 1.00 51.90  ? 46  LYS A HZ2  1 
ATOM   539  H  HZ3  . LYS A 1 35  ? 142.682 157.430 145.478 1.00 51.65  ? 46  LYS A HZ3  1 
ATOM   540  N  N    . ASP A 1 36  ? 148.806 159.672 149.394 1.00 43.87  ? 47  ASP A N    1 
ATOM   541  C  CA   . ASP A 1 36  ? 149.156 160.960 149.968 1.00 39.64  ? 47  ASP A CA   1 
ATOM   542  C  C    . ASP A 1 36  ? 147.967 161.910 149.887 1.00 36.97  ? 47  ASP A C    1 
ATOM   543  O  O    . ASP A 1 36  ? 147.006 161.686 149.146 1.00 50.26  ? 47  ASP A O    1 
ATOM   544  C  CB   . ASP A 1 36  ? 150.361 161.558 149.247 1.00 42.67  ? 47  ASP A CB   1 
ATOM   545  C  CG   . ASP A 1 36  ? 151.674 161.028 149.775 1.00 49.84  ? 47  ASP A CG   1 
ATOM   546  O  OD1  . ASP A 1 36  ? 151.660 159.995 150.476 1.00 55.12  ? 47  ASP A OD1  1 
ATOM   547  O  OD2  . ASP A 1 36  ? 152.723 161.642 149.489 1.00 54.21  ? 47  ASP A OD2  1 
ATOM   548  H  H    . ASP A 1 36  ? 149.273 159.447 148.708 1.00 46.39  ? 47  ASP A H    1 
ATOM   549  H  HA   . ASP A 1 36  ? 149.387 160.842 150.903 1.00 45.98  ? 47  ASP A HA   1 
ATOM   550  H  HB2  . ASP A 1 36  ? 150.309 161.334 148.305 1.00 45.75  ? 47  ASP A HB2  1 
ATOM   551  H  HB3  . ASP A 1 36  ? 150.356 162.521 149.362 1.00 46.28  ? 47  ASP A HB3  1 
ATOM   552  N  N    . VAL A 1 37  ? 148.037 162.983 150.668 1.00 26.16  ? 48  VAL A N    1 
ATOM   553  C  CA   . VAL A 1 37  ? 146.945 163.939 150.770 1.00 27.77  ? 48  VAL A CA   1 
ATOM   554  C  C    . VAL A 1 37  ? 147.500 165.353 150.695 1.00 30.00  ? 48  VAL A C    1 
ATOM   555  O  O    . VAL A 1 37  ? 148.615 165.635 151.145 1.00 47.16  ? 48  VAL A O    1 
ATOM   556  C  CB   . VAL A 1 37  ? 146.139 163.735 152.071 1.00 39.16  ? 48  VAL A CB   1 
ATOM   557  C  CG1  . VAL A 1 37  ? 145.232 164.927 152.339 1.00 41.31  ? 48  VAL A CG1  1 
ATOM   558  C  CG2  . VAL A 1 37  ? 145.333 162.446 151.992 1.00 42.29  ? 48  VAL A CG2  1 
ATOM   559  H  H    . VAL A 1 37  ? 148.718 163.181 151.155 1.00 42.30  ? 48  VAL A H    1 
ATOM   560  H  HA   . VAL A 1 37  ? 146.341 163.815 150.022 1.00 41.83  ? 48  VAL A HA   1 
ATOM   561  H  HB   . VAL A 1 37  ? 146.757 163.656 152.814 1.00 43.14  ? 48  VAL A HB   1 
ATOM   562  H  HG11 . VAL A 1 37  ? 144.555 164.667 152.983 1.00 42.75  ? 48  VAL A HG11 1 
ATOM   563  H  HG12 . VAL A 1 37  ? 145.760 165.658 152.695 1.00 40.62  ? 48  VAL A HG12 1 
ATOM   564  H  HG13 . VAL A 1 37  ? 144.809 165.193 151.509 1.00 42.41  ? 48  VAL A HG13 1 
ATOM   565  H  HG21 . VAL A 1 37  ? 144.817 162.343 152.806 1.00 44.63  ? 48  VAL A HG21 1 
ATOM   566  H  HG22 . VAL A 1 37  ? 144.738 162.494 151.227 1.00 43.10  ? 48  VAL A HG22 1 
ATOM   567  H  HG23 . VAL A 1 37  ? 145.943 161.699 151.890 1.00 41.75  ? 48  VAL A HG23 1 
ATOM   568  N  N    . PHE A 1 38  ? 146.715 166.242 150.099 1.00 33.39  ? 49  PHE A N    1 
ATOM   569  C  CA   . PHE A 1 38  ? 147.010 167.664 150.056 1.00 45.23  ? 49  PHE A CA   1 
ATOM   570  C  C    . PHE A 1 38  ? 145.777 168.420 150.523 1.00 54.93  ? 49  PHE A C    1 
ATOM   571  O  O    . PHE A 1 38  ? 144.647 167.972 150.318 1.00 56.36  ? 49  PHE A O    1 
ATOM   572  C  CB   . PHE A 1 38  ? 147.411 168.110 148.643 1.00 49.20  ? 49  PHE A CB   1 
ATOM   573  C  CG   . PHE A 1 38  ? 147.699 169.579 148.525 1.00 42.37  ? 49  PHE A CG   1 
ATOM   574  C  CD1  . PHE A 1 38  ? 148.949 170.079 148.832 1.00 44.15  ? 49  PHE A CD1  1 
ATOM   575  C  CD2  . PHE A 1 38  ? 146.723 170.456 148.090 1.00 45.86  ? 49  PHE A CD2  1 
ATOM   576  C  CE1  . PHE A 1 38  ? 149.218 171.427 148.718 1.00 48.55  ? 49  PHE A CE1  1 
ATOM   577  C  CE2  . PHE A 1 38  ? 146.987 171.803 147.974 1.00 44.70  ? 49  PHE A CE2  1 
ATOM   578  C  CZ   . PHE A 1 38  ? 148.235 172.289 148.288 1.00 45.76  ? 49  PHE A CZ   1 
ATOM   579  H  H    . PHE A 1 38  ? 145.980 166.036 149.701 1.00 47.04  ? 49  PHE A H    1 
ATOM   580  H  HA   . PHE A 1 38  ? 147.741 167.863 150.660 1.00 47.11  ? 49  PHE A HA   1 
ATOM   581  H  HB2  . PHE A 1 38  ? 148.211 167.630 148.379 1.00 47.54  ? 49  PHE A HB2  1 
ATOM   582  H  HB3  . PHE A 1 38  ? 146.686 167.901 148.033 1.00 49.55  ? 49  PHE A HB3  1 
ATOM   583  H  HD1  . PHE A 1 38  ? 149.615 169.501 149.122 1.00 47.98  ? 49  PHE A HD1  1 
ATOM   584  H  HD2  . PHE A 1 38  ? 145.877 170.134 147.876 1.00 48.17  ? 49  PHE A HD2  1 
ATOM   585  H  HE1  . PHE A 1 38  ? 150.062 171.752 148.931 1.00 48.23  ? 49  PHE A HE1  1 
ATOM   586  H  HE2  . PHE A 1 38  ? 146.321 172.384 147.683 1.00 47.80  ? 49  PHE A HE2  1 
ATOM   587  H  HZ   . PHE A 1 38  ? 148.415 173.198 148.211 1.00 47.71  ? 49  PHE A HZ   1 
ATOM   588  N  N    . VAL A 1 39  ? 146.000 169.552 151.183 1.00 62.87  ? 50  VAL A N    1 
ATOM   589  C  CA   . VAL A 1 39  ? 144.911 170.394 151.665 1.00 55.66  ? 50  VAL A CA   1 
ATOM   590  C  C    . VAL A 1 39  ? 145.304 171.851 151.482 1.00 60.65  ? 50  VAL A C    1 
ATOM   591  O  O    . VAL A 1 39  ? 146.430 172.244 151.806 1.00 64.76  ? 50  VAL A O    1 
ATOM   592  C  CB   . VAL A 1 39  ? 144.571 170.115 153.141 1.00 54.23  ? 50  VAL A CB   1 
ATOM   593  C  CG1  . VAL A 1 39  ? 143.353 170.921 153.571 1.00 58.79  ? 50  VAL A CG1  1 
ATOM   594  C  CG2  . VAL A 1 39  ? 144.344 168.629 153.368 1.00 50.41  ? 50  VAL A CG2  1 
ATOM   595  H  H    . VAL A 1 39  ? 146.783 169.859 151.365 1.00 58.33  ? 50  VAL A H    1 
ATOM   596  H  HA   . VAL A 1 39  ? 144.117 170.226 151.134 1.00 57.24  ? 50  VAL A HA   1 
ATOM   597  H  HB   . VAL A 1 39  ? 145.315 170.400 153.686 1.00 58.02  ? 50  VAL A HB   1 
ATOM   598  H  HG11 . VAL A 1 39  ? 143.115 170.672 154.477 1.00 58.65  ? 50  VAL A HG11 1 
ATOM   599  H  HG12 . VAL A 1 39  ? 143.566 171.867 153.534 1.00 58.48  ? 50  VAL A HG12 1 
ATOM   600  H  HG13 . VAL A 1 39  ? 142.618 170.723 152.971 1.00 57.83  ? 50  VAL A HG13 1 
ATOM   601  H  HG21 . VAL A 1 39  ? 144.033 168.493 154.277 1.00 57.28  ? 50  VAL A HG21 1 
ATOM   602  H  HG22 . VAL A 1 39  ? 143.675 168.313 152.740 1.00 57.55  ? 50  VAL A HG22 1 
ATOM   603  H  HG23 . VAL A 1 39  ? 145.179 168.156 153.229 1.00 56.20  ? 50  VAL A HG23 1 
ATOM   604  N  N    . CYS A 1 40  ? 144.373 172.652 150.966 1.00 74.57  ? 51  CYS A N    1 
ATOM   605  C  CA   . CYS A 1 40  ? 144.546 174.096 150.814 1.00 79.66  ? 51  CYS A CA   1 
ATOM   606  C  C    . CYS A 1 40  ? 143.311 174.751 151.424 1.00 79.37  ? 51  CYS A C    1 
ATOM   607  O  O    . CYS A 1 40  ? 142.332 175.026 150.725 1.00 84.08  ? 51  CYS A O    1 
ATOM   608  C  CB   . CYS A 1 40  ? 144.737 174.480 149.351 1.00 78.86  ? 51  CYS A CB   1 
ATOM   609  S  SG   . CYS A 1 40  ? 144.727 176.260 149.043 1.00 82.41  ? 51  CYS A SG   1 
ATOM   610  H  H    . CYS A 1 40  ? 143.609 172.372 150.687 1.00 75.08  ? 51  CYS A H    1 
ATOM   611  H  HA   . CYS A 1 40  ? 145.325 174.384 151.311 1.00 76.04  ? 51  CYS A HA   1 
ATOM   612  H  HB2  . CYS A 1 40  ? 145.591 174.134 149.049 1.00 75.58  ? 51  CYS A HB2  1 
ATOM   613  H  HB3  . CYS A 1 40  ? 144.023 174.085 148.829 1.00 75.96  ? 51  CYS A HB3  1 
ATOM   614  H  HG   . CYS A 1 40  ? 145.612 176.763 149.677 1.00 76.30  ? 51  CYS A HG   1 
ATOM   615  N  N    . MET A 1 41  ? 143.363 174.998 152.733 1.00 69.48  ? 52  MET A N    1 
ATOM   616  C  CA   . MET A 1 41  ? 142.259 175.580 153.470 1.00 68.49  ? 52  MET A CA   1 
ATOM   617  C  C    . MET A 1 41  ? 142.712 176.854 154.175 1.00 72.46  ? 52  MET A C    1 
ATOM   618  O  O    . MET A 1 41  ? 143.830 176.903 154.699 1.00 76.95  ? 52  MET A O    1 
ATOM   619  C  CB   . MET A 1 41  ? 141.716 174.589 154.508 1.00 68.07  ? 52  MET A CB   1 
ATOM   620  C  CG   . MET A 1 41  ? 140.691 173.614 153.961 1.00 71.03  ? 52  MET A CG   1 
ATOM   621  S  SD   . MET A 1 41  ? 140.528 172.140 154.987 1.00 70.26  ? 52  MET A SD   1 
ATOM   622  C  CE   . MET A 1 41  ? 139.897 170.964 153.792 1.00 74.18  ? 52  MET A CE   1 
ATOM   623  H  H    . MET A 1 41  ? 144.049 174.830 153.223 1.00 70.71  ? 52  MET A H    1 
ATOM   624  H  HA   . MET A 1 41  ? 141.543 175.785 152.850 1.00 70.23  ? 52  MET A HA   1 
ATOM   625  H  HB2  . MET A 1 41  ? 142.457 174.070 154.857 1.00 69.97  ? 52  MET A HB2  1 
ATOM   626  H  HB3  . MET A 1 41  ? 141.297 175.088 155.227 1.00 70.00  ? 52  MET A HB3  1 
ATOM   627  H  HG2  . MET A 1 41  ? 139.826 174.051 153.922 1.00 70.57  ? 52  MET A HG2  1 
ATOM   628  H  HG3  . MET A 1 41  ? 140.962 173.334 153.073 1.00 70.88  ? 52  MET A HG3  1 
ATOM   629  H  HE1  . MET A 1 41  ? 140.033 170.067 154.133 1.00 71.13  ? 52  MET A HE1  1 
ATOM   630  H  HE2  . MET A 1 41  ? 138.950 171.128 153.658 1.00 71.40  ? 52  MET A HE2  1 
ATOM   631  H  HE3  . MET A 1 41  ? 140.375 171.076 152.956 1.00 71.02  ? 52  MET A HE3  1 
ATOM   632  N  N    . PRO A 1 42  ? 141.876 177.888 154.219 1.00 72.00  ? 53  PRO A N    1 
ATOM   633  C  CA   . PRO A 1 42  ? 142.307 179.156 154.813 1.00 76.40  ? 53  PRO A CA   1 
ATOM   634  C  C    . PRO A 1 42  ? 142.505 179.034 156.315 1.00 74.35  ? 53  PRO A C    1 
ATOM   635  O  O    . PRO A 1 42  ? 141.949 178.158 156.980 1.00 74.37  ? 53  PRO A O    1 
ATOM   636  C  CB   . PRO A 1 42  ? 141.163 180.117 154.476 1.00 76.65  ? 53  PRO A CB   1 
ATOM   637  C  CG   . PRO A 1 42  ? 139.974 179.245 154.315 1.00 77.45  ? 53  PRO A CG   1 
ATOM   638  C  CD   . PRO A 1 42  ? 140.477 177.942 153.761 1.00 70.96  ? 53  PRO A CD   1 
ATOM   639  H  HA   . PRO A 1 42  ? 143.127 179.467 154.399 1.00 74.04  ? 53  PRO A HA   1 
ATOM   640  H  HB2  . PRO A 1 42  ? 141.034 180.744 155.205 1.00 73.68  ? 53  PRO A HB2  1 
ATOM   641  H  HB3  . PRO A 1 42  ? 141.360 180.585 153.650 1.00 74.24  ? 53  PRO A HB3  1 
ATOM   642  H  HG2  . PRO A 1 42  ? 139.553 179.109 155.178 1.00 74.26  ? 53  PRO A HG2  1 
ATOM   643  H  HG3  . PRO A 1 42  ? 139.352 179.658 153.696 1.00 74.46  ? 53  PRO A HG3  1 
ATOM   644  H  HD2  . PRO A 1 42  ? 139.972 177.199 154.127 1.00 72.74  ? 53  PRO A HD2  1 
ATOM   645  H  HD3  . PRO A 1 42  ? 140.444 177.955 152.792 1.00 73.46  ? 53  PRO A HD3  1 
ATOM   646  N  N    . THR A 1 43  ? 143.324 179.940 156.847 1.00 74.79  ? 54  THR A N    1 
ATOM   647  C  CA   . THR A 1 43  ? 143.608 179.941 158.275 1.00 73.85  ? 54  THR A CA   1 
ATOM   648  C  C    . THR A 1 43  ? 142.311 180.046 159.065 1.00 78.14  ? 54  THR A C    1 
ATOM   649  O  O    . THR A 1 43  ? 141.439 180.860 158.747 1.00 77.83  ? 54  THR A O    1 
ATOM   650  C  CB   . THR A 1 43  ? 144.541 181.100 158.628 1.00 75.25  ? 54  THR A CB   1 
ATOM   651  O  OG1  . THR A 1 43  ? 145.772 180.963 157.907 1.00 75.20  ? 54  THR A OG1  1 
ATOM   652  C  CG2  . THR A 1 43  ? 144.834 181.122 160.124 1.00 72.49  ? 54  THR A CG2  1 
ATOM   653  H  H    . THR A 1 43  ? 143.723 180.559 156.404 1.00 75.64  ? 54  THR A H    1 
ATOM   654  H  HA   . THR A 1 43  ? 144.047 179.110 158.516 1.00 74.94  ? 54  THR A HA   1 
ATOM   655  H  HB   . THR A 1 43  ? 144.118 181.939 158.386 1.00 75.70  ? 54  THR A HB   1 
ATOM   656  H  HG1  . THR A 1 43  ? 146.291 181.594 158.103 1.00 75.24  ? 54  THR A HG1  1 
ATOM   657  H  HG21 . THR A 1 43  ? 145.524 181.777 160.314 1.00 74.89  ? 54  THR A HG21 1 
ATOM   658  H  HG22 . THR A 1 43  ? 144.035 181.357 160.621 1.00 74.68  ? 54  THR A HG22 1 
ATOM   659  H  HG23 . THR A 1 43  ? 145.143 180.249 160.415 1.00 74.82  ? 54  THR A HG23 1 
ATOM   660  N  N    . GLY A 1 44  ? 142.187 179.218 160.099 1.00 89.76  ? 55  GLY A N    1 
ATOM   661  C  CA   . GLY A 1 44  ? 140.971 179.161 160.881 1.00 89.31  ? 55  GLY A CA   1 
ATOM   662  C  C    . GLY A 1 44  ? 139.884 178.286 160.302 1.00 88.98  ? 55  GLY A C    1 
ATOM   663  O  O    . GLY A 1 44  ? 138.769 178.279 160.835 1.00 91.15  ? 55  GLY A O    1 
ATOM   664  H  H    . GLY A 1 44  ? 142.801 178.677 160.364 1.00 87.66  ? 55  GLY A H    1 
ATOM   665  H  HA2  . GLY A 1 44  ? 141.183 178.827 161.766 1.00 87.84  ? 55  GLY A HA2  1 
ATOM   666  H  HA3  . GLY A 1 44  ? 140.615 180.058 160.975 1.00 87.75  ? 55  GLY A HA3  1 
ATOM   667  N  N    . ALA A 1 45  ? 140.169 177.547 159.231 1.00 75.31  ? 56  ALA A N    1 
ATOM   668  C  CA   . ALA A 1 45  ? 139.197 176.666 158.600 1.00 77.72  ? 56  ALA A CA   1 
ATOM   669  C  C    . ALA A 1 45  ? 139.342 175.219 159.050 1.00 74.54  ? 56  ALA A C    1 
ATOM   670  O  O    . ALA A 1 45  ? 138.764 174.325 158.423 1.00 74.94  ? 56  ALA A O    1 
ATOM   671  C  CB   . ALA A 1 45  ? 139.319 176.750 157.078 1.00 77.55  ? 56  ALA A CB   1 
ATOM   672  H  H    . ALA A 1 45  ? 140.937 177.539 158.845 1.00 75.72  ? 56  ALA A H    1 
ATOM   673  H  HA   . ALA A 1 45  ? 138.305 176.961 158.841 1.00 76.70  ? 56  ALA A HA   1 
ATOM   674  H  HB1  . ALA A 1 45  ? 138.651 176.174 156.676 1.00 75.67  ? 56  ALA A HB1  1 
ATOM   675  H  HB2  . ALA A 1 45  ? 139.175 177.668 156.804 1.00 75.59  ? 56  ALA A HB2  1 
ATOM   676  H  HB3  . ALA A 1 45  ? 140.207 176.460 156.816 1.00 76.06  ? 56  ALA A HB3  1 
ATOM   677  N  N    . GLY A 1 46  ? 140.101 174.966 160.112 1.00 67.85  ? 57  GLY A N    1 
ATOM   678  C  CA   . GLY A 1 46  ? 140.288 173.611 160.584 1.00 68.52  ? 57  GLY A CA   1 
ATOM   679  C  C    . GLY A 1 46  ? 141.294 172.805 159.801 1.00 69.98  ? 57  GLY A C    1 
ATOM   680  O  O    . GLY A 1 46  ? 141.314 171.576 159.923 1.00 75.20  ? 57  GLY A O    1 
ATOM   681  H  H    . GLY A 1 46  ? 140.516 175.563 160.572 1.00 71.90  ? 57  GLY A H    1 
ATOM   682  H  HA2  . GLY A 1 46  ? 140.580 173.637 161.509 1.00 71.60  ? 57  GLY A HA2  1 
ATOM   683  H  HA3  . GLY A 1 46  ? 139.439 173.145 160.550 1.00 72.06  ? 57  GLY A HA3  1 
ATOM   684  N  N    . LYS A 1 47  ? 142.132 173.457 158.990 1.00 77.24  ? 58  LYS A N    1 
ATOM   685  C  CA   . LYS A 1 47  ? 143.138 172.723 158.231 1.00 81.51  ? 58  LYS A CA   1 
ATOM   686  C  C    . LYS A 1 47  ? 144.032 171.900 159.145 1.00 76.66  ? 58  LYS A C    1 
ATOM   687  O  O    . LYS A 1 47  ? 144.486 170.817 158.759 1.00 76.72  ? 58  LYS A O    1 
ATOM   688  C  CB   . LYS A 1 47  ? 143.984 173.691 157.401 1.00 80.19  ? 58  LYS A CB   1 
ATOM   689  C  CG   . LYS A 1 47  ? 144.872 174.612 158.226 1.00 78.68  ? 58  LYS A CG   1 
ATOM   690  C  CD   . LYS A 1 47  ? 145.665 175.558 157.341 1.00 76.26  ? 58  LYS A CD   1 
ATOM   691  C  CE   . LYS A 1 47  ? 146.520 176.505 158.167 1.00 77.01  ? 58  LYS A CE   1 
ATOM   692  N  NZ   . LYS A 1 47  ? 147.605 175.790 158.895 1.00 77.48  ? 58  LYS A NZ   1 
ATOM   693  H  H    . LYS A 1 47  ? 142.136 174.307 158.865 1.00 76.45  ? 58  LYS A H    1 
ATOM   694  H  HA   . LYS A 1 47  ? 142.693 172.116 157.620 1.00 76.70  ? 58  LYS A HA   1 
ATOM   695  H  HB2  . LYS A 1 47  ? 144.557 173.178 156.811 1.00 76.51  ? 58  LYS A HB2  1 
ATOM   696  H  HB3  . LYS A 1 47  ? 143.390 174.251 156.877 1.00 76.57  ? 58  LYS A HB3  1 
ATOM   697  H  HG2  . LYS A 1 47  ? 144.319 175.143 158.821 1.00 77.14  ? 58  LYS A HG2  1 
ATOM   698  H  HG3  . LYS A 1 47  ? 145.503 174.082 158.737 1.00 76.60  ? 58  LYS A HG3  1 
ATOM   699  H  HD2  . LYS A 1 47  ? 146.251 175.043 156.765 1.00 76.27  ? 58  LYS A HD2  1 
ATOM   700  H  HD3  . LYS A 1 47  ? 145.051 176.089 156.808 1.00 76.40  ? 58  LYS A HD3  1 
ATOM   701  H  HE2  . LYS A 1 47  ? 146.931 177.159 157.579 1.00 76.60  ? 58  LYS A HE2  1 
ATOM   702  H  HE3  . LYS A 1 47  ? 145.960 176.950 158.822 1.00 76.57  ? 58  LYS A HE3  1 
ATOM   703  H  HZ1  . LYS A 1 47  ? 148.086 176.369 159.369 1.00 76.89  ? 58  LYS A HZ1  1 
ATOM   704  H  HZ2  . LYS A 1 47  ? 147.254 175.186 159.447 1.00 76.61  ? 58  LYS A HZ2  1 
ATOM   705  H  HZ3  . LYS A 1 47  ? 148.138 175.376 158.315 1.00 76.96  ? 58  LYS A HZ3  1 
ATOM   706  N  N    . SER A 1 48  ? 144.298 172.393 160.356 1.00 69.78  ? 59  SER A N    1 
ATOM   707  C  CA   . SER A 1 48  ? 145.154 171.657 161.279 1.00 73.65  ? 59  SER A CA   1 
ATOM   708  C  C    . SER A 1 48  ? 144.544 170.306 161.628 1.00 71.62  ? 59  SER A C    1 
ATOM   709  O  O    . SER A 1 48  ? 145.217 169.272 161.560 1.00 77.48  ? 59  SER A O    1 
ATOM   710  C  CB   . SER A 1 48  ? 145.391 172.485 162.542 1.00 76.20  ? 59  SER A CB   1 
ATOM   711  O  OG   . SER A 1 48  ? 144.349 172.292 163.483 1.00 75.95  ? 59  SER A OG   1 
ATOM   712  H  H    . SER A 1 48  ? 144.000 173.140 160.660 1.00 73.42  ? 59  SER A H    1 
ATOM   713  H  HA   . SER A 1 48  ? 146.009 171.503 160.852 1.00 73.93  ? 59  SER A HA   1 
ATOM   714  H  HB2  . SER A 1 48  ? 146.231 172.213 162.944 1.00 73.87  ? 59  SER A HB2  1 
ATOM   715  H  HB3  . SER A 1 48  ? 145.428 173.424 162.302 1.00 74.43  ? 59  SER A HB3  1 
ATOM   716  H  HG   . SER A 1 48  ? 144.492 172.753 164.170 1.00 73.32  ? 59  SER A HG   1 
ATOM   717  N  N    . LEU A 1 49  ? 143.255 170.291 161.971 1.00 68.25  ? 60  LEU A N    1 
ATOM   718  C  CA   . LEU A 1 49  ? 142.624 169.048 162.397 1.00 66.92  ? 60  LEU A CA   1 
ATOM   719  C  C    . LEU A 1 49  ? 142.829 167.941 161.373 1.00 69.42  ? 60  LEU A C    1 
ATOM   720  O  O    . LEU A 1 49  ? 142.997 166.775 161.747 1.00 75.95  ? 60  LEU A O    1 
ATOM   721  C  CB   . LEU A 1 49  ? 141.131 169.277 162.642 1.00 74.86  ? 60  LEU A CB   1 
ATOM   722  C  CG   . LEU A 1 49  ? 140.296 168.044 162.997 1.00 75.90  ? 60  LEU A CG   1 
ATOM   723  C  CD1  . LEU A 1 49  ? 140.688 167.500 164.362 1.00 76.88  ? 60  LEU A CD1  1 
ATOM   724  C  CD2  . LEU A 1 49  ? 138.814 168.383 162.958 1.00 73.48  ? 60  LEU A CD2  1 
ATOM   725  H  H    . LEU A 1 49  ? 142.734 170.975 161.965 1.00 73.33  ? 60  LEU A H    1 
ATOM   726  H  HA   . LEU A 1 49  ? 143.027 168.763 163.231 1.00 72.44  ? 60  LEU A HA   1 
ATOM   727  H  HB2  . LEU A 1 49  ? 141.037 169.908 163.373 1.00 73.95  ? 60  LEU A HB2  1 
ATOM   728  H  HB3  . LEU A 1 49  ? 140.748 169.661 161.837 1.00 73.68  ? 60  LEU A HB3  1 
ATOM   729  H  HG   . LEU A 1 49  ? 140.455 167.348 162.341 1.00 73.66  ? 60  LEU A HG   1 
ATOM   730  H  HD11 . LEU A 1 49  ? 140.373 166.587 164.440 1.00 73.82  ? 60  LEU A HD11 1 
ATOM   731  H  HD12 . LEU A 1 49  ? 141.654 167.521 164.449 1.00 73.98  ? 60  LEU A HD12 1 
ATOM   732  H  HD13 . LEU A 1 49  ? 140.284 168.052 165.050 1.00 74.51  ? 60  LEU A HD13 1 
ATOM   733  H  HD21 . LEU A 1 49  ? 138.617 169.012 163.670 1.00 73.81  ? 60  LEU A HD21 1 
ATOM   734  H  HD22 . LEU A 1 49  ? 138.603 168.778 162.098 1.00 73.62  ? 60  LEU A HD22 1 
ATOM   735  H  HD23 . LEU A 1 49  ? 138.301 167.570 163.084 1.00 73.45  ? 60  LEU A HD23 1 
ATOM   736  N  N    . CYS A 1 50  ? 142.853 168.293 160.085 1.00 64.67  ? 61  CYS A N    1 
ATOM   737  C  CA   . CYS A 1 50  ? 142.984 167.289 159.035 1.00 64.60  ? 61  CYS A CA   1 
ATOM   738  C  C    . CYS A 1 50  ? 144.209 166.412 159.250 1.00 65.12  ? 61  CYS A C    1 
ATOM   739  O  O    . CYS A 1 50  ? 144.149 165.192 159.059 1.00 65.07  ? 61  CYS A O    1 
ATOM   740  C  CB   . CYS A 1 50  ? 143.057 167.972 157.670 1.00 72.23  ? 61  CYS A CB   1 
ATOM   741  S  SG   . CYS A 1 50  ? 141.450 168.373 156.962 1.00 81.66  ? 61  CYS A SG   1 
ATOM   742  H  H    . CYS A 1 50  ? 142.794 169.101 159.798 1.00 69.81  ? 61  CYS A H    1 
ATOM   743  H  HA   . CYS A 1 50  ? 142.200 166.718 159.044 1.00 69.48  ? 61  CYS A HA   1 
ATOM   744  H  HB2  . CYS A 1 50  ? 143.554 168.800 157.761 1.00 70.13  ? 61  CYS A HB2  1 
ATOM   745  H  HB3  . CYS A 1 50  ? 143.514 167.382 157.050 1.00 70.13  ? 61  CYS A HB3  1 
ATOM   746  H  HG   . CYS A 1 50  ? 140.820 167.356 156.895 1.00 71.07  ? 61  CYS A HG   1 
ATOM   747  N  N    . TYR A 1 51  ? 145.334 167.013 159.634 1.00 69.22  ? 62  TYR A N    1 
ATOM   748  C  CA   . TYR A 1 51  ? 146.552 166.256 159.886 1.00 67.25  ? 62  TYR A CA   1 
ATOM   749  C  C    . TYR A 1 51  ? 146.718 165.860 161.345 1.00 67.43  ? 62  TYR A C    1 
ATOM   750  O  O    . TYR A 1 51  ? 147.453 164.909 161.632 1.00 61.30  ? 62  TYR A O    1 
ATOM   751  C  CB   . TYR A 1 51  ? 147.775 167.060 159.433 1.00 63.51  ? 62  TYR A CB   1 
ATOM   752  C  CG   . TYR A 1 51  ? 148.301 168.050 160.449 1.00 59.92  ? 62  TYR A CG   1 
ATOM   753  C  CD1  . TYR A 1 51  ? 149.254 167.681 161.388 1.00 59.03  ? 62  TYR A CD1  1 
ATOM   754  C  CD2  . TYR A 1 51  ? 147.859 169.364 160.454 1.00 66.60  ? 62  TYR A CD2  1 
ATOM   755  C  CE1  . TYR A 1 51  ? 149.736 168.590 162.308 1.00 65.41  ? 62  TYR A CE1  1 
ATOM   756  C  CE2  . TYR A 1 51  ? 148.339 170.277 161.365 1.00 64.53  ? 62  TYR A CE2  1 
ATOM   757  C  CZ   . TYR A 1 51  ? 149.277 169.888 162.287 1.00 68.86  ? 62  TYR A CZ   1 
ATOM   758  O  OH   . TYR A 1 51  ? 149.748 170.803 163.198 1.00 72.25  ? 62  TYR A OH   1 
ATOM   759  H  H    . TYR A 1 51  ? 145.415 167.861 159.756 1.00 67.64  ? 62  TYR A H    1 
ATOM   760  H  HA   . TYR A 1 51  ? 146.527 165.441 159.361 1.00 66.46  ? 62  TYR A HA   1 
ATOM   761  H  HB2  . TYR A 1 51  ? 148.492 166.440 159.228 1.00 65.70  ? 62  TYR A HB2  1 
ATOM   762  H  HB3  . TYR A 1 51  ? 147.538 167.558 158.635 1.00 66.72  ? 62  TYR A HB3  1 
ATOM   763  H  HD1  . TYR A 1 51  ? 149.567 166.805 161.403 1.00 64.99  ? 62  TYR A HD1  1 
ATOM   764  H  HD2  . TYR A 1 51  ? 147.225 169.634 159.830 1.00 67.29  ? 62  TYR A HD2  1 
ATOM   765  H  HE1  . TYR A 1 51  ? 150.371 168.331 162.934 1.00 65.98  ? 62  TYR A HE1  1 
ATOM   766  H  HE2  . TYR A 1 51  ? 148.029 171.154 161.357 1.00 65.74  ? 62  TYR A HE2  1 
ATOM   767  H  HH   . TYR A 1 51  ? 150.085 170.405 163.854 1.00 66.69  ? 62  TYR A HH   1 
ATOM   768  N  N    . GLN A 1 52  ? 146.060 166.560 162.269 1.00 86.00  ? 63  GLN A N    1 
ATOM   769  C  CA   . GLN A 1 52  ? 146.199 166.218 163.681 1.00 81.12  ? 63  GLN A CA   1 
ATOM   770  C  C    . GLN A 1 52  ? 145.425 164.949 164.026 1.00 81.14  ? 63  GLN A C    1 
ATOM   771  O  O    . GLN A 1 52  ? 145.969 164.038 164.659 1.00 89.88  ? 63  GLN A O    1 
ATOM   772  C  CB   . GLN A 1 52  ? 145.734 167.382 164.560 1.00 81.68  ? 63  GLN A CB   1 
ATOM   773  C  CG   . GLN A 1 52  ? 146.298 168.744 164.167 1.00 84.40  ? 63  GLN A CG   1 
ATOM   774  C  CD   . GLN A 1 52  ? 147.557 169.104 164.917 1.00 83.65  ? 63  GLN A CD   1 
ATOM   775  O  OE1  . GLN A 1 52  ? 148.246 168.238 165.451 1.00 83.85  ? 63  GLN A OE1  1 
ATOM   776  N  NE2  . GLN A 1 52  ? 147.869 170.394 164.958 1.00 83.29  ? 63  GLN A NE2  1 
ATOM   777  H  H    . GLN A 1 52  ? 145.536 167.223 162.108 1.00 81.55  ? 63  GLN A H    1 
ATOM   778  H  HA   . GLN A 1 52  ? 147.136 166.056 163.873 1.00 81.41  ? 63  GLN A HA   1 
ATOM   779  H  HB2  . GLN A 1 52  ? 144.767 167.441 164.509 1.00 81.03  ? 63  GLN A HB2  1 
ATOM   780  H  HB3  . GLN A 1 52  ? 146.002 167.206 165.475 1.00 81.62  ? 63  GLN A HB3  1 
ATOM   781  H  HG2  . GLN A 1 52  ? 146.536 168.735 163.231 1.00 81.09  ? 63  GLN A HG2  1 
ATOM   782  H  HG3  . GLN A 1 52  ? 145.632 169.429 164.339 1.00 81.69  ? 63  GLN A HG3  1 
ATOM   783  H  HE21 . GLN A 1 52  ? 147.363 170.972 164.572 1.00 81.67  ? 63  GLN A HE21 1 
ATOM   784  H  HE22 . GLN A 1 52  ? 148.577 170.652 165.373 1.00 81.24  ? 63  GLN A HE22 1 
ATOM   785  N  N    . LEU A 1 53  ? 144.159 164.867 163.615 1.00 75.38  ? 64  LEU A N    1 
ATOM   786  C  CA   . LEU A 1 53  ? 143.331 163.726 164.003 1.00 74.30  ? 64  LEU A CA   1 
ATOM   787  C  C    . LEU A 1 53  ? 143.877 162.401 163.492 1.00 75.63  ? 64  LEU A C    1 
ATOM   788  O  O    . LEU A 1 53  ? 143.919 161.433 164.273 1.00 76.67  ? 64  LEU A O    1 
ATOM   789  C  CB   . LEU A 1 53  ? 141.892 163.947 163.529 1.00 75.79  ? 64  LEU A CB   1 
ATOM   790  C  CG   . LEU A 1 53  ? 140.827 163.078 164.202 1.00 81.72  ? 64  LEU A CG   1 
ATOM   791  C  CD1  . LEU A 1 53  ? 140.746 163.348 165.697 1.00 82.96  ? 64  LEU A CD1  1 
ATOM   792  C  CD2  . LEU A 1 53  ? 139.475 163.302 163.547 1.00 85.41  ? 64  LEU A CD2  1 
ATOM   793  H  H    . LEU A 1 53  ? 143.762 165.447 163.119 1.00 77.95  ? 64  LEU A H    1 
ATOM   794  H  HA   . LEU A 1 53  ? 143.322 163.679 164.971 1.00 78.21  ? 64  LEU A HA   1 
ATOM   795  H  HB2  . LEU A 1 53  ? 141.657 164.873 163.695 1.00 78.13  ? 64  LEU A HB2  1 
ATOM   796  H  HB3  . LEU A 1 53  ? 141.845 163.770 162.578 1.00 78.21  ? 64  LEU A HB3  1 
ATOM   797  H  HG   . LEU A 1 53  ? 141.063 162.145 164.082 1.00 78.74  ? 64  LEU A HG   1 
ATOM   798  H  HD11 . LEU A 1 53  ? 140.008 162.840 166.066 1.00 79.35  ? 64  LEU A HD11 1 
ATOM   799  H  HD12 . LEU A 1 53  ? 141.575 163.074 166.118 1.00 78.94  ? 64  LEU A HD12 1 
ATOM   800  H  HD13 . LEU A 1 53  ? 140.598 164.296 165.839 1.00 79.60  ? 64  LEU A HD13 1 
ATOM   801  H  HD21 . LEU A 1 53  ? 138.814 162.754 163.996 1.00 79.63  ? 64  LEU A HD21 1 
ATOM   802  H  HD22 . LEU A 1 53  ? 139.238 164.240 163.624 1.00 79.48  ? 64  LEU A HD22 1 
ATOM   803  H  HD23 . LEU A 1 53  ? 139.531 163.049 162.613 1.00 79.34  ? 64  LEU A HD23 1 
ATOM   804  N  N    . PRO A 1 54  ? 144.277 162.265 162.225 1.00 69.77  ? 65  PRO A N    1 
ATOM   805  C  CA   . PRO A 1 54  ? 144.857 160.983 161.796 1.00 71.85  ? 65  PRO A CA   1 
ATOM   806  C  C    . PRO A 1 54  ? 146.084 160.601 162.598 1.00 70.56  ? 65  PRO A C    1 
ATOM   807  O  O    . PRO A 1 54  ? 146.286 159.417 162.896 1.00 74.85  ? 65  PRO A O    1 
ATOM   808  C  CB   . PRO A 1 54  ? 145.188 161.222 160.316 1.00 74.06  ? 65  PRO A CB   1 
ATOM   809  C  CG   . PRO A 1 54  ? 144.376 162.404 159.913 1.00 75.36  ? 65  PRO A CG   1 
ATOM   810  C  CD   . PRO A 1 54  ? 144.244 163.249 161.133 1.00 73.67  ? 65  PRO A CD   1 
ATOM   811  H  HA   . PRO A 1 54  ? 144.197 160.276 161.865 1.00 72.43  ? 65  PRO A HA   1 
ATOM   812  H  HB2  . PRO A 1 54  ? 146.135 161.409 160.220 1.00 71.34  ? 65  PRO A HB2  1 
ATOM   813  H  HB3  . PRO A 1 54  ? 144.940 160.442 159.796 1.00 71.91  ? 65  PRO A HB3  1 
ATOM   814  H  HG2  . PRO A 1 54  ? 144.836 162.891 159.214 1.00 71.78  ? 65  PRO A HG2  1 
ATOM   815  H  HG3  . PRO A 1 54  ? 143.504 162.109 159.606 1.00 72.05  ? 65  PRO A HG3  1 
ATOM   816  H  HD2  . PRO A 1 54  ? 144.996 163.855 161.204 1.00 72.52  ? 65  PRO A HD2  1 
ATOM   817  H  HD3  . PRO A 1 54  ? 143.402 163.727 161.122 1.00 72.88  ? 65  PRO A HD3  1 
ATOM   818  N  N    . ALA A 1 55  ? 146.910 161.581 162.968 1.00 64.62  ? 66  ALA A N    1 
ATOM   819  C  CA   . ALA A 1 55  ? 148.043 161.297 163.839 1.00 67.91  ? 66  ALA A CA   1 
ATOM   820  C  C    . ALA A 1 55  ? 147.569 160.780 165.190 1.00 70.41  ? 66  ALA A C    1 
ATOM   821  O  O    . ALA A 1 55  ? 148.162 159.853 165.754 1.00 67.57  ? 66  ALA A O    1 
ATOM   822  C  CB   . ALA A 1 55  ? 148.893 162.554 164.016 1.00 69.16  ? 66  ALA A CB   1 
ATOM   823  H  H    . ALA A 1 55  ? 146.837 162.404 162.729 1.00 68.30  ? 66  ALA A H    1 
ATOM   824  H  HA   . ALA A 1 55  ? 148.595 160.612 163.431 1.00 68.32  ? 66  ALA A HA   1 
ATOM   825  H  HB1  . ALA A 1 55  ? 149.652 162.344 164.582 1.00 68.55  ? 66  ALA A HB1  1 
ATOM   826  H  HB2  . ALA A 1 55  ? 149.199 162.854 163.146 1.00 68.29  ? 66  ALA A HB2  1 
ATOM   827  H  HB3  . ALA A 1 55  ? 148.352 163.244 164.429 1.00 68.77  ? 66  ALA A HB3  1 
ATOM   828  N  N    . LEU A 1 56  ? 146.498 161.371 165.724 1.00 78.98  ? 67  LEU A N    1 
ATOM   829  C  CA   . LEU A 1 56  ? 145.951 160.905 166.993 1.00 75.29  ? 67  LEU A CA   1 
ATOM   830  C  C    . LEU A 1 56  ? 145.490 159.458 166.892 1.00 72.03  ? 67  LEU A C    1 
ATOM   831  O  O    . LEU A 1 56  ? 145.751 158.650 167.791 1.00 70.67  ? 67  LEU A O    1 
ATOM   832  C  CB   . LEU A 1 56  ? 144.787 161.799 167.417 1.00 76.06  ? 67  LEU A CB   1 
ATOM   833  C  CG   . LEU A 1 56  ? 145.091 162.995 168.321 1.00 78.92  ? 67  LEU A CG   1 
ATOM   834  C  CD1  . LEU A 1 56  ? 145.632 162.539 169.668 1.00 76.02  ? 67  LEU A CD1  1 
ATOM   835  C  CD2  . LEU A 1 56  ? 146.051 163.970 167.651 1.00 80.46  ? 67  LEU A CD2  1 
ATOM   836  H  H    . LEU A 1 56  ? 146.078 162.035 165.374 1.00 76.54  ? 67  LEU A H    1 
ATOM   837  H  HA   . LEU A 1 56  ? 146.641 160.955 167.673 1.00 75.29  ? 67  LEU A HA   1 
ATOM   838  H  HB2  . LEU A 1 56  ? 144.371 162.150 166.615 1.00 75.90  ? 67  LEU A HB2  1 
ATOM   839  H  HB3  . LEU A 1 56  ? 144.145 161.246 167.889 1.00 75.39  ? 67  LEU A HB3  1 
ATOM   840  H  HG   . LEU A 1 56  ? 144.262 163.468 168.479 1.00 75.93  ? 67  LEU A HG   1 
ATOM   841  H  HD11 . LEU A 1 56  ? 145.619 163.290 170.282 1.00 75.78  ? 67  LEU A HD11 1 
ATOM   842  H  HD12 . LEU A 1 56  ? 145.070 161.825 170.007 1.00 75.75  ? 67  LEU A HD12 1 
ATOM   843  H  HD13 . LEU A 1 56  ? 146.541 162.219 169.554 1.00 75.48  ? 67  LEU A HD13 1 
ATOM   844  H  HD21 . LEU A 1 56  ? 146.392 164.585 168.318 1.00 76.09  ? 67  LEU A HD21 1 
ATOM   845  H  HD22 . LEU A 1 56  ? 146.782 163.475 167.251 1.00 76.25  ? 67  LEU A HD22 1 
ATOM   846  H  HD23 . LEU A 1 56  ? 145.570 164.461 166.967 1.00 76.81  ? 67  LEU A HD23 1 
ATOM   847  N  N    . LEU A 1 57  ? 144.805 159.113 165.805 1.00 68.77  ? 68  LEU A N    1 
ATOM   848  C  CA   . LEU A 1 57  ? 144.238 157.783 165.632 1.00 70.86  ? 68  LEU A CA   1 
ATOM   849  C  C    . LEU A 1 57  ? 145.177 156.825 164.913 1.00 61.91  ? 68  LEU A C    1 
ATOM   850  O  O    . LEU A 1 57  ? 144.799 155.674 164.674 1.00 58.10  ? 68  LEU A O    1 
ATOM   851  C  CB   . LEU A 1 57  ? 142.916 157.872 164.863 1.00 68.22  ? 68  LEU A CB   1 
ATOM   852  H  H    . LEU A 1 57  ? 144.654 159.642 165.144 1.00 68.00  ? 68  LEU A H    1 
ATOM   853  H  HA   . LEU A 1 57  ? 144.047 157.408 166.506 1.00 68.41  ? 68  LEU A HA   1 
ATOM   854  N  N    . ALA A 1 58  ? 146.383 157.264 164.570 1.00 61.20  ? 69  ALA A N    1 
ATOM   855  C  CA   . ALA A 1 58  ? 147.323 156.417 163.854 1.00 68.54  ? 69  ALA A CA   1 
ATOM   856  C  C    . ALA A 1 58  ? 148.029 155.456 164.803 1.00 68.49  ? 69  ALA A C    1 
ATOM   857  O  O    . ALA A 1 58  ? 148.289 155.773 165.967 1.00 67.78  ? 69  ALA A O    1 
ATOM   858  C  CB   . ALA A 1 58  ? 148.357 157.268 163.122 1.00 67.66  ? 69  ALA A CB   1 
ATOM   859  H  H    . ALA A 1 58  ? 146.683 158.051 164.743 1.00 66.03  ? 69  ALA A H    1 
ATOM   860  H  HA   . ALA A 1 58  ? 146.842 155.893 163.195 1.00 67.18  ? 69  ALA A HA   1 
ATOM   861  H  HB1  . ALA A 1 58  ? 149.017 156.674 162.740 1.00 66.51  ? 69  ALA A HB1  1 
ATOM   862  H  HB2  . ALA A 1 58  ? 147.919 157.772 162.420 1.00 66.79  ? 69  ALA A HB2  1 
ATOM   863  H  HB3  . ALA A 1 58  ? 148.780 157.869 163.755 1.00 67.08  ? 69  ALA A HB3  1 
ATOM   864  N  N    . LYS A 1 59  ? 148.339 154.264 164.286 1.00 63.58  ? 70  LYS A N    1 
ATOM   865  C  CA   . LYS A 1 59  ? 149.021 153.254 165.085 1.00 62.97  ? 70  LYS A CA   1 
ATOM   866  C  C    . LYS A 1 59  ? 150.481 153.604 165.339 1.00 63.72  ? 70  LYS A C    1 
ATOM   867  O  O    . LYS A 1 59  ? 151.091 153.037 166.251 1.00 63.00  ? 70  LYS A O    1 
ATOM   868  C  CB   . LYS A 1 59  ? 148.923 151.893 164.394 1.00 60.77  ? 70  LYS A CB   1 
ATOM   869  C  CG   . LYS A 1 59  ? 149.525 150.725 165.174 1.00 63.94  ? 70  LYS A CG   1 
ATOM   870  C  CD   . LYS A 1 59  ? 148.852 150.511 166.528 1.00 64.51  ? 70  LYS A CD   1 
ATOM   871  C  CE   . LYS A 1 59  ? 147.416 150.024 166.384 1.00 66.19  ? 70  LYS A CE   1 
ATOM   872  N  NZ   . LYS A 1 59  ? 147.337 148.675 165.761 1.00 67.46  ? 70  LYS A NZ   1 
ATOM   873  H  H    . LYS A 1 59  ? 148.165 154.021 163.480 1.00 63.81  ? 70  LYS A H    1 
ATOM   874  H  HA   . LYS A 1 59  ? 148.576 153.192 165.944 1.00 64.45  ? 70  LYS A HA   1 
ATOM   875  H  HB2  . LYS A 1 59  ? 147.988 151.694 164.233 1.00 63.38  ? 70  LYS A HB2  1 
ATOM   876  H  HB3  . LYS A 1 59  ? 149.392 151.947 163.546 1.00 63.53  ? 70  LYS A HB3  1 
ATOM   877  H  HG2  . LYS A 1 59  ? 149.416 149.913 164.656 1.00 64.45  ? 70  LYS A HG2  1 
ATOM   878  H  HG3  . LYS A 1 59  ? 150.467 150.893 165.329 1.00 63.47  ? 70  LYS A HG3  1 
ATOM   879  H  HD2  . LYS A 1 59  ? 149.346 149.838 167.020 1.00 63.94  ? 70  LYS A HD2  1 
ATOM   880  H  HD3  . LYS A 1 59  ? 148.844 151.343 167.026 1.00 63.60  ? 70  LYS A HD3  1 
ATOM   881  H  HE2  . LYS A 1 59  ? 147.013 149.971 167.265 1.00 63.81  ? 70  LYS A HE2  1 
ATOM   882  H  HE3  . LYS A 1 59  ? 146.918 150.644 165.830 1.00 64.18  ? 70  LYS A HE3  1 
ATOM   883  H  HZ1  . LYS A 1 59  ? 147.807 148.091 166.241 1.00 64.62  ? 70  LYS A HZ1  1 
ATOM   884  H  HZ2  . LYS A 1 59  ? 147.666 148.702 164.935 1.00 64.36  ? 70  LYS A HZ2  1 
ATOM   885  H  HZ3  . LYS A 1 59  ? 146.490 148.406 165.726 1.00 64.24  ? 70  LYS A HZ3  1 
ATOM   886  N  N    . GLY A 1 60  ? 151.050 154.518 164.558 1.00 73.03  ? 71  GLY A N    1 
ATOM   887  C  CA   . GLY A 1 60  ? 152.428 154.930 164.744 1.00 74.14  ? 71  GLY A CA   1 
ATOM   888  C  C    . GLY A 1 60  ? 152.543 156.354 165.244 1.00 75.12  ? 71  GLY A C    1 
ATOM   889  O  O    . GLY A 1 60  ? 151.835 156.749 166.175 1.00 80.74  ? 71  GLY A O    1 
ATOM   890  H  H    . GLY A 1 60  ? 150.651 154.916 163.910 1.00 73.05  ? 71  GLY A H    1 
ATOM   891  H  HA2  . GLY A 1 60  ? 152.865 154.343 165.381 1.00 73.27  ? 71  GLY A HA2  1 
ATOM   892  H  HA3  . GLY A 1 60  ? 152.895 154.864 163.897 1.00 73.89  ? 71  GLY A HA3  1 
ATOM   893  N  N    . ILE A 1 61  ? 153.432 157.136 164.635 1.00 67.00  ? 72  ILE A N    1 
ATOM   894  C  CA   . ILE A 1 61  ? 153.626 158.534 164.992 1.00 65.48  ? 72  ILE A CA   1 
ATOM   895  C  C    . ILE A 1 61  ? 153.687 159.369 163.722 1.00 59.45  ? 72  ILE A C    1 
ATOM   896  O  O    . ILE A 1 61  ? 154.099 158.891 162.661 1.00 68.11  ? 72  ILE A O    1 
ATOM   897  C  CB   . ILE A 1 61  ? 154.896 158.735 165.845 1.00 69.20  ? 72  ILE A CB   1 
ATOM   898  C  CG1  . ILE A 1 61  ? 156.146 158.318 165.065 1.00 67.78  ? 72  ILE A CG1  1 
ATOM   899  C  CG2  . ILE A 1 61  ? 154.786 157.952 167.139 1.00 73.39  ? 72  ILE A CG2  1 
ATOM   900  C  CD1  . ILE A 1 61  ? 157.440 158.699 165.744 1.00 70.87  ? 72  ILE A CD1  1 
ATOM   901  H  H    . ILE A 1 61  ? 153.946 156.870 163.999 1.00 69.08  ? 72  ILE A H    1 
ATOM   902  H  HA   . ILE A 1 61  ? 152.865 158.837 165.512 1.00 69.36  ? 72  ILE A HA   1 
ATOM   903  H  HB   . ILE A 1 61  ? 154.972 159.677 166.063 1.00 69.18  ? 72  ILE A HB   1 
ATOM   904  H  HG12 . ILE A 1 61  ? 156.140 157.354 164.959 1.00 68.72  ? 72  ILE A HG12 1 
ATOM   905  H  HG13 . ILE A 1 61  ? 156.142 158.744 164.195 1.00 68.98  ? 72  ILE A HG13 1 
ATOM   906  H  HG21 . ILE A 1 61  ? 155.517 158.207 167.719 1.00 69.81  ? 72  ILE A HG21 1 
ATOM   907  H  HG22 . ILE A 1 61  ? 153.939 158.163 167.563 1.00 69.79  ? 72  ILE A HG22 1 
ATOM   908  H  HG23 . ILE A 1 61  ? 154.830 157.003 166.941 1.00 69.31  ? 72  ILE A HG23 1 
ATOM   909  H  HD11 . ILE A 1 61  ? 158.178 158.372 165.208 1.00 69.54  ? 72  ILE A HD11 1 
ATOM   910  H  HD12 . ILE A 1 61  ? 157.486 159.665 165.820 1.00 69.46  ? 72  ILE A HD12 1 
ATOM   911  H  HD13 . ILE A 1 61  ? 157.471 158.294 166.624 1.00 68.91  ? 72  ILE A HD13 1 
ATOM   912  N  N    . THR A 1 62  ? 153.272 160.627 163.838 1.00 44.92  ? 73  THR A N    1 
ATOM   913  C  CA   . THR A 1 62  ? 153.184 161.539 162.705 1.00 52.01  ? 73  THR A CA   1 
ATOM   914  C  C    . THR A 1 62  ? 154.195 162.664 162.879 1.00 48.92  ? 73  THR A C    1 
ATOM   915  O  O    . THR A 1 62  ? 154.192 163.352 163.905 1.00 62.13  ? 73  THR A O    1 
ATOM   916  C  CB   . THR A 1 62  ? 151.772 162.109 162.570 1.00 51.26  ? 73  THR A CB   1 
ATOM   917  O  OG1  . THR A 1 62  ? 150.841 161.038 162.371 1.00 58.52  ? 73  THR A OG1  1 
ATOM   918  C  CG2  . THR A 1 62  ? 151.692 163.074 161.394 1.00 59.93  ? 73  THR A CG2  1 
ATOM   919  H  H    . THR A 1 62  ? 153.029 160.983 164.583 1.00 56.14  ? 73  THR A H    1 
ATOM   920  H  HA   . THR A 1 62  ? 153.395 161.059 161.893 1.00 57.91  ? 73  THR A HA   1 
ATOM   921  H  HB   . THR A 1 62  ? 151.544 162.594 163.378 1.00 55.77  ? 73  THR A HB   1 
ATOM   922  H  HG1  . THR A 1 62  ? 150.104 161.342 162.106 1.00 57.51  ? 73  THR A HG1  1 
ATOM   923  H  HG21 . THR A 1 62  ? 150.764 163.284 161.203 1.00 57.47  ? 73  THR A HG21 1 
ATOM   924  H  HG22 . THR A 1 62  ? 152.163 163.896 161.601 1.00 56.98  ? 73  THR A HG22 1 
ATOM   925  H  HG23 . THR A 1 62  ? 152.090 162.670 160.606 1.00 57.44  ? 73  THR A HG23 1 
ATOM   926  N  N    . ILE A 1 63  ? 155.044 162.852 161.874 1.00 39.20  ? 74  ILE A N    1 
ATOM   927  C  CA   . ILE A 1 63  ? 156.029 163.927 161.870 1.00 33.45  ? 74  ILE A CA   1 
ATOM   928  C  C    . ILE A 1 63  ? 155.423 165.118 161.142 1.00 43.49  ? 74  ILE A C    1 
ATOM   929  O  O    . ILE A 1 63  ? 154.980 164.997 159.994 1.00 58.51  ? 74  ILE A O    1 
ATOM   930  C  CB   . ILE A 1 63  ? 157.341 163.478 161.209 1.00 46.35  ? 74  ILE A CB   1 
ATOM   931  C  CG1  . ILE A 1 63  ? 158.180 162.675 162.207 1.00 57.07  ? 74  ILE A CG1  1 
ATOM   932  C  CG2  . ILE A 1 63  ? 158.124 164.684 160.702 1.00 53.78  ? 74  ILE A CG2  1 
ATOM   933  C  CD1  . ILE A 1 63  ? 159.489 162.154 161.646 1.00 53.51  ? 74  ILE A CD1  1 
ATOM   934  H  H    . ILE A 1 63  ? 155.069 162.360 161.169 1.00 52.68  ? 74  ILE A H    1 
ATOM   935  H  HA   . ILE A 1 63  ? 156.223 164.189 162.782 1.00 50.69  ? 74  ILE A HA   1 
ATOM   936  H  HB   . ILE A 1 63  ? 157.128 162.909 160.453 1.00 51.90  ? 74  ILE A HB   1 
ATOM   937  H  HG12 . ILE A 1 63  ? 158.396 163.250 162.958 1.00 53.45  ? 74  ILE A HG12 1 
ATOM   938  H  HG13 . ILE A 1 63  ? 157.663 161.917 162.518 1.00 52.76  ? 74  ILE A HG13 1 
ATOM   939  H  HG21 . ILE A 1 63  ? 159.032 164.419 160.494 1.00 52.90  ? 74  ILE A HG21 1 
ATOM   940  H  HG22 . ILE A 1 63  ? 157.700 165.028 159.900 1.00 52.75  ? 74  ILE A HG22 1 
ATOM   941  H  HG23 . ILE A 1 63  ? 158.133 165.366 161.392 1.00 52.28  ? 74  ILE A HG23 1 
ATOM   942  H  HD11 . ILE A 1 63  ? 159.785 161.402 162.183 1.00 51.60  ? 74  ILE A HD11 1 
ATOM   943  H  HD12 . ILE A 1 63  ? 159.347 161.870 160.729 1.00 52.22  ? 74  ILE A HD12 1 
ATOM   944  H  HD13 . ILE A 1 63  ? 160.150 162.863 161.674 1.00 52.29  ? 74  ILE A HD13 1 
ATOM   945  N  N    . VAL A 1 64  ? 155.404 166.267 161.808 1.00 56.07  ? 75  VAL A N    1 
ATOM   946  C  CA   . VAL A 1 64  ? 154.823 167.494 161.274 1.00 57.86  ? 75  VAL A CA   1 
ATOM   947  C  C    . VAL A 1 64  ? 155.943 168.515 161.163 1.00 53.46  ? 75  VAL A C    1 
ATOM   948  O  O    . VAL A 1 64  ? 156.488 168.959 162.181 1.00 66.97  ? 75  VAL A O    1 
ATOM   949  C  CB   . VAL A 1 64  ? 153.687 168.024 162.158 1.00 65.44  ? 75  VAL A CB   1 
ATOM   950  C  CG1  . VAL A 1 64  ? 152.887 169.089 161.420 1.00 64.22  ? 75  VAL A CG1  1 
ATOM   951  C  CG2  . VAL A 1 64  ? 152.787 166.882 162.611 1.00 66.55  ? 75  VAL A CG2  1 
ATOM   952  H  H    . VAL A 1 64  ? 155.734 166.364 162.596 1.00 61.73  ? 75  VAL A H    1 
ATOM   953  H  HA   . VAL A 1 64  ? 154.472 167.330 160.386 1.00 61.15  ? 75  VAL A HA   1 
ATOM   954  H  HB   . VAL A 1 64  ? 154.070 168.434 162.949 1.00 62.52  ? 75  VAL A HB   1 
ATOM   955  H  HG11 . VAL A 1 64  ? 152.345 169.576 162.060 1.00 62.43  ? 75  VAL A HG11 1 
ATOM   956  H  HG12 . VAL A 1 64  ? 153.499 169.697 160.976 1.00 62.22  ? 75  VAL A HG12 1 
ATOM   957  H  HG13 . VAL A 1 64  ? 152.318 168.657 160.765 1.00 62.43  ? 75  VAL A HG13 1 
ATOM   958  H  HG21 . VAL A 1 64  ? 152.060 167.246 163.138 1.00 62.74  ? 75  VAL A HG21 1 
ATOM   959  H  HG22 . VAL A 1 64  ? 152.437 166.427 161.829 1.00 62.32  ? 75  VAL A HG22 1 
ATOM   960  H  HG23 . VAL A 1 64  ? 153.303 166.264 163.151 1.00 62.54  ? 75  VAL A HG23 1 
ATOM   961  N  N    . VAL A 1 65  ? 156.277 168.903 159.939 1.00 35.44  ? 76  VAL A N    1 
ATOM   962  C  CA   . VAL A 1 65  ? 157.349 169.857 159.685 1.00 43.33  ? 76  VAL A CA   1 
ATOM   963  C  C    . VAL A 1 65  ? 156.722 171.182 159.280 1.00 51.33  ? 76  VAL A C    1 
ATOM   964  O  O    . VAL A 1 65  ? 155.940 171.247 158.323 1.00 64.23  ? 76  VAL A O    1 
ATOM   965  C  CB   . VAL A 1 65  ? 158.322 169.338 158.614 1.00 54.33  ? 76  VAL A CB   1 
ATOM   966  C  CG1  . VAL A 1 65  ? 157.614 169.157 157.286 1.00 55.66  ? 76  VAL A CG1  1 
ATOM   967  C  CG2  . VAL A 1 65  ? 159.510 170.283 158.477 1.00 59.86  ? 76  VAL A CG2  1 
ATOM   968  H  H    . VAL A 1 65  ? 155.887 168.621 159.228 1.00 54.60  ? 76  VAL A H    1 
ATOM   969  H  HA   . VAL A 1 65  ? 157.852 169.998 160.501 1.00 55.66  ? 76  VAL A HA   1 
ATOM   970  H  HB   . VAL A 1 65  ? 158.660 168.472 158.890 1.00 56.23  ? 76  VAL A HB   1 
ATOM   971  H  HG11 . VAL A 1 65  ? 158.167 168.605 156.712 1.00 55.76  ? 76  VAL A HG11 1 
ATOM   972  H  HG12 . VAL A 1 65  ? 156.770 168.716 157.438 1.00 56.44  ? 76  VAL A HG12 1 
ATOM   973  H  HG13 . VAL A 1 65  ? 157.466 170.025 156.880 1.00 55.81  ? 76  VAL A HG13 1 
ATOM   974  H  HG21 . VAL A 1 65  ? 160.173 169.873 157.900 1.00 55.77  ? 76  VAL A HG21 1 
ATOM   975  H  HG22 . VAL A 1 65  ? 159.208 171.120 158.091 1.00 55.92  ? 76  VAL A HG22 1 
ATOM   976  H  HG23 . VAL A 1 65  ? 159.890 170.440 159.355 1.00 56.47  ? 76  VAL A HG23 1 
ATOM   977  N  N    . SER A 1 66  ? 157.060 172.235 160.015 1.00 68.95  ? 77  SER A N    1 
ATOM   978  C  CA   . SER A 1 66  ? 156.516 173.569 159.833 1.00 67.89  ? 77  SER A CA   1 
ATOM   979  C  C    . SER A 1 66  ? 157.660 174.569 159.757 1.00 69.57  ? 77  SER A C    1 
ATOM   980  O  O    . SER A 1 66  ? 158.701 174.369 160.391 1.00 78.47  ? 77  SER A O    1 
ATOM   981  C  CB   . SER A 1 66  ? 155.577 173.927 160.994 1.00 71.97  ? 77  SER A CB   1 
ATOM   982  O  OG   . SER A 1 66  ? 155.055 175.231 160.864 1.00 78.31  ? 77  SER A OG   1 
ATOM   983  H  H    . SER A 1 66  ? 157.632 172.195 160.656 1.00 71.65  ? 77  SER A H    1 
ATOM   984  H  HA   . SER A 1 66  ? 156.012 173.606 159.006 1.00 70.98  ? 77  SER A HA   1 
ATOM   985  H  HB2  . SER A 1 66  ? 154.841 173.295 161.005 1.00 71.66  ? 77  SER A HB2  1 
ATOM   986  H  HB3  . SER A 1 66  ? 156.072 173.868 161.824 1.00 71.44  ? 77  SER A HB3  1 
ATOM   987  H  HG   . SER A 1 66  ? 154.827 175.520 161.616 1.00 72.85  ? 77  SER A HG   1 
ATOM   988  N  N    . PRO A 1 67  ? 157.499 175.660 159.001 1.00 73.76  ? 78  PRO A N    1 
ATOM   989  C  CA   . PRO A 1 67  ? 158.678 176.488 158.701 1.00 79.49  ? 78  PRO A CA   1 
ATOM   990  C  C    . PRO A 1 67  ? 159.179 177.286 159.890 1.00 76.43  ? 78  PRO A C    1 
ATOM   991  O  O    . PRO A 1 67  ? 160.397 177.425 160.062 1.00 76.71  ? 78  PRO A O    1 
ATOM   992  C  CB   . PRO A 1 67  ? 158.189 177.397 157.565 1.00 78.85  ? 78  PRO A CB   1 
ATOM   993  C  CG   . PRO A 1 67  ? 156.717 177.468 157.723 1.00 76.13  ? 78  PRO A CG   1 
ATOM   994  C  CD   . PRO A 1 67  ? 156.254 176.261 158.487 1.00 75.55  ? 78  PRO A CD   1 
ATOM   995  H  HA   . PRO A 1 67  ? 159.399 175.929 158.370 1.00 76.33  ? 78  PRO A HA   1 
ATOM   996  H  HB2  . PRO A 1 67  ? 158.585 178.277 157.659 1.00 76.77  ? 78  PRO A HB2  1 
ATOM   997  H  HB3  . PRO A 1 67  ? 158.424 177.005 156.709 1.00 75.96  ? 78  PRO A HB3  1 
ATOM   998  H  HG2  . PRO A 1 67  ? 156.489 178.276 158.210 1.00 76.02  ? 78  PRO A HG2  1 
ATOM   999  H  HG3  . PRO A 1 67  ? 156.306 177.483 156.845 1.00 75.66  ? 78  PRO A HG3  1 
ATOM   1000 H  HD2  . PRO A 1 67  ? 155.691 176.553 159.216 1.00 75.89  ? 78  PRO A HD2  1 
ATOM   1001 H  HD3  . PRO A 1 67  ? 155.784 175.648 157.904 1.00 75.79  ? 78  PRO A HD3  1 
ATOM   1002 N  N    . LEU A 1 68  ? 158.284 177.814 160.718 1.00 72.27  ? 79  LEU A N    1 
ATOM   1003 C  CA   . LEU A 1 68  ? 158.659 178.704 161.807 1.00 76.68  ? 79  LEU A CA   1 
ATOM   1004 C  C    . LEU A 1 68  ? 158.685 177.955 163.133 1.00 77.90  ? 79  LEU A C    1 
ATOM   1005 O  O    . LEU A 1 68  ? 157.852 177.079 163.383 1.00 81.53  ? 79  LEU A O    1 
ATOM   1006 C  CB   . LEU A 1 68  ? 157.690 179.884 161.902 1.00 82.65  ? 79  LEU A CB   1 
ATOM   1007 C  CG   . LEU A 1 68  ? 157.990 181.087 161.001 1.00 80.58  ? 79  LEU A CG   1 
ATOM   1008 C  CD1  . LEU A 1 68  ? 159.294 181.758 161.409 1.00 79.75  ? 79  LEU A CD1  1 
ATOM   1009 C  CD2  . LEU A 1 68  ? 158.033 180.672 159.538 1.00 76.38  ? 79  LEU A CD2  1 
ATOM   1010 H  H    . LEU A 1 68  ? 157.438 177.668 160.667 1.00 77.29  ? 79  LEU A H    1 
ATOM   1011 H  HA   . LEU A 1 68  ? 159.548 179.051 161.642 1.00 77.66  ? 79  LEU A HA   1 
ATOM   1012 H  HB2  . LEU A 1 68  ? 156.802 179.568 161.673 1.00 78.40  ? 79  LEU A HB2  1 
ATOM   1013 H  HB3  . LEU A 1 68  ? 157.690 180.204 162.818 1.00 78.47  ? 79  LEU A HB3  1 
ATOM   1014 H  HG   . LEU A 1 68  ? 157.278 181.738 161.104 1.00 78.30  ? 79  LEU A HG   1 
ATOM   1015 H  HD11 . LEU A 1 68  ? 159.369 182.608 160.947 1.00 78.20  ? 79  LEU A HD11 1 
ATOM   1016 H  HD12 . LEU A 1 68  ? 159.288 181.903 162.368 1.00 78.22  ? 79  LEU A HD12 1 
ATOM   1017 H  HD13 . LEU A 1 68  ? 160.037 181.183 161.167 1.00 78.36  ? 79  LEU A HD13 1 
ATOM   1018 H  HD21 . LEU A 1 68  ? 158.141 181.465 158.990 1.00 77.42  ? 79  LEU A HD21 1 
ATOM   1019 H  HD22 . LEU A 1 68  ? 158.782 180.071 159.401 1.00 78.10  ? 79  LEU A HD22 1 
ATOM   1020 H  HD23 . LEU A 1 68  ? 157.202 180.225 159.313 1.00 77.83  ? 79  LEU A HD23 1 
ATOM   1021 N  N    . ILE A 1 69  ? 159.653 178.311 163.980 1.00 78.46  ? 80  ILE A N    1 
ATOM   1022 C  CA   . ILE A 1 69  ? 159.719 177.740 165.322 1.00 75.48  ? 80  ILE A CA   1 
ATOM   1023 C  C    . ILE A 1 69  ? 158.484 178.128 166.124 1.00 73.62  ? 80  ILE A C    1 
ATOM   1024 O  O    . ILE A 1 69  ? 157.923 177.311 166.866 1.00 73.74  ? 80  ILE A O    1 
ATOM   1025 C  CB   . ILE A 1 69  ? 161.016 178.182 166.026 1.00 77.14  ? 80  ILE A CB   1 
ATOM   1026 C  CG1  . ILE A 1 69  ? 161.162 177.487 167.382 1.00 76.72  ? 80  ILE A CG1  1 
ATOM   1027 C  CG2  . ILE A 1 69  ? 161.042 179.694 166.215 1.00 76.86  ? 80  ILE A CG2  1 
ATOM   1028 C  CD1  . ILE A 1 69  ? 161.160 175.983 167.306 1.00 77.57  ? 80  ILE A CD1  1 
ATOM   1029 H  H    . ILE A 1 69  ? 160.277 178.875 163.801 1.00 77.10  ? 80  ILE A H    1 
ATOM   1030 H  HA   . ILE A 1 69  ? 159.730 176.774 165.241 1.00 76.30  ? 80  ILE A HA   1 
ATOM   1031 H  HB   . ILE A 1 69  ? 161.769 177.929 165.469 1.00 76.82  ? 80  ILE A HB   1 
ATOM   1032 H  HG12 . ILE A 1 69  ? 162.004 177.759 167.780 1.00 76.66  ? 80  ILE A HG12 1 
ATOM   1033 H  HG13 . ILE A 1 69  ? 160.428 177.756 167.957 1.00 76.62  ? 80  ILE A HG13 1 
ATOM   1034 H  HG21 . ILE A 1 69  ? 161.937 179.961 166.478 1.00 76.86  ? 80  ILE A HG21 1 
ATOM   1035 H  HG22 . ILE A 1 69  ? 160.802 180.126 165.381 1.00 76.63  ? 80  ILE A HG22 1 
ATOM   1036 H  HG23 . ILE A 1 69  ? 160.410 179.938 166.908 1.00 76.55  ? 80  ILE A HG23 1 
ATOM   1037 H  HD11 . ILE A 1 69  ? 161.491 175.627 168.145 1.00 76.73  ? 80  ILE A HD11 1 
ATOM   1038 H  HD12 . ILE A 1 69  ? 160.254 175.673 167.150 1.00 76.80  ? 80  ILE A HD12 1 
ATOM   1039 H  HD13 . ILE A 1 69  ? 161.737 175.706 166.577 1.00 76.59  ? 80  ILE A HD13 1 
ATOM   1040 N  N    . ALA A 1 70  ? 158.047 179.381 165.993 1.00 77.83  ? 81  ALA A N    1 
ATOM   1041 C  CA   . ALA A 1 70  ? 156.876 179.833 166.735 1.00 79.75  ? 81  ALA A CA   1 
ATOM   1042 C  C    . ALA A 1 70  ? 155.640 179.038 166.342 1.00 78.03  ? 81  ALA A C    1 
ATOM   1043 O  O    . ALA A 1 70  ? 154.824 178.684 167.199 1.00 75.18  ? 81  ALA A O    1 
ATOM   1044 C  CB   . ALA A 1 70  ? 156.653 181.327 166.500 1.00 80.18  ? 81  ALA A CB   1 
ATOM   1045 H  H    . ALA A 1 70  ? 158.405 179.978 165.489 1.00 77.70  ? 81  ALA A H    1 
ATOM   1046 H  HA   . ALA A 1 70  ? 157.031 179.698 167.683 1.00 77.78  ? 81  ALA A HA   1 
ATOM   1047 H  HB1  . ALA A 1 70  ? 155.869 181.610 166.995 1.00 78.08  ? 81  ALA A HB1  1 
ATOM   1048 H  HB2  . ALA A 1 70  ? 157.433 181.814 166.807 1.00 77.80  ? 81  ALA A HB2  1 
ATOM   1049 H  HB3  . ALA A 1 70  ? 156.519 181.480 165.551 1.00 78.10  ? 81  ALA A HB3  1 
ATOM   1050 N  N    . LEU A 1 71  ? 155.479 178.753 165.049 1.00 80.52  ? 82  LEU A N    1 
ATOM   1051 C  CA   . LEU A 1 71  ? 154.335 177.963 164.603 1.00 82.79  ? 82  LEU A CA   1 
ATOM   1052 C  C    . LEU A 1 71  ? 154.377 176.560 165.198 1.00 79.61  ? 82  LEU A C    1 
ATOM   1053 O  O    . LEU A 1 71  ? 153.351 176.034 165.650 1.00 79.35  ? 82  LEU A O    1 
ATOM   1054 C  CB   . LEU A 1 71  ? 154.315 177.911 163.075 1.00 81.09  ? 82  LEU A CB   1 
ATOM   1055 C  CG   . LEU A 1 71  ? 152.986 177.596 162.382 1.00 81.37  ? 82  LEU A CG   1 
ATOM   1056 C  CD1  . LEU A 1 71  ? 153.080 177.917 160.896 1.00 76.51  ? 82  LEU A CD1  1 
ATOM   1057 C  CD2  . LEU A 1 71  ? 152.567 176.148 162.584 1.00 80.13  ? 82  LEU A CD2  1 
ATOM   1058 H  H    . LEU A 1 71  ? 156.009 179.003 164.419 1.00 78.98  ? 82  LEU A H    1 
ATOM   1059 H  HA   . LEU A 1 71  ? 153.518 178.392 164.901 1.00 79.95  ? 82  LEU A HA   1 
ATOM   1060 H  HB2  . LEU A 1 71  ? 154.606 178.776 162.746 1.00 78.73  ? 82  LEU A HB2  1 
ATOM   1061 H  HB3  . LEU A 1 71  ? 154.952 177.236 162.791 1.00 79.41  ? 82  LEU A HB3  1 
ATOM   1062 H  HG   . LEU A 1 71  ? 152.294 178.159 162.763 1.00 79.47  ? 82  LEU A HG   1 
ATOM   1063 H  HD11 . LEU A 1 71  ? 152.187 177.921 160.517 1.00 78.51  ? 82  LEU A HD11 1 
ATOM   1064 H  HD12 . LEU A 1 71  ? 153.490 178.789 160.785 1.00 79.15  ? 82  LEU A HD12 1 
ATOM   1065 H  HD13 . LEU A 1 71  ? 153.622 177.240 160.461 1.00 78.40  ? 82  LEU A HD13 1 
ATOM   1066 H  HD21 . LEU A 1 71  ? 152.255 175.791 161.738 1.00 79.21  ? 82  LEU A HD21 1 
ATOM   1067 H  HD22 . LEU A 1 71  ? 153.327 175.635 162.899 1.00 78.88  ? 82  LEU A HD22 1 
ATOM   1068 H  HD23 . LEU A 1 71  ? 151.855 176.117 163.240 1.00 79.33  ? 82  LEU A HD23 1 
ATOM   1069 N  N    . ILE A 1 72  ? 155.559 175.939 165.208 1.00 85.36  ? 83  ILE A N    1 
ATOM   1070 C  CA   . ILE A 1 72  ? 155.699 174.607 165.790 1.00 88.41  ? 83  ILE A CA   1 
ATOM   1071 C  C    . ILE A 1 72  ? 155.315 174.635 167.262 1.00 87.80  ? 83  ILE A C    1 
ATOM   1072 O  O    . ILE A 1 72  ? 154.564 173.777 167.747 1.00 87.39  ? 83  ILE A O    1 
ATOM   1073 C  CB   . ILE A 1 72  ? 157.135 174.086 165.595 1.00 87.15  ? 83  ILE A CB   1 
ATOM   1074 C  CG1  . ILE A 1 72  ? 157.446 173.918 164.106 1.00 83.21  ? 83  ILE A CG1  1 
ATOM   1075 C  CG2  . ILE A 1 72  ? 157.327 172.780 166.347 1.00 83.31  ? 83  ILE A CG2  1 
ATOM   1076 C  CD1  . ILE A 1 72  ? 158.919 173.744 163.800 1.00 81.86  ? 83  ILE A CD1  1 
ATOM   1077 H  H    . ILE A 1 72  ? 156.287 176.265 164.887 1.00 83.23  ? 83  ILE A H    1 
ATOM   1078 H  HA   . ILE A 1 72  ? 155.097 173.997 165.335 1.00 83.45  ? 83  ILE A HA   1 
ATOM   1079 H  HB   . ILE A 1 72  ? 157.750 174.741 165.961 1.00 83.66  ? 83  ILE A HB   1 
ATOM   1080 H  HG12 . ILE A 1 72  ? 156.982 173.131 163.778 1.00 82.52  ? 83  ILE A HG12 1 
ATOM   1081 H  HG13 . ILE A 1 72  ? 157.138 174.704 163.630 1.00 82.79  ? 83  ILE A HG13 1 
ATOM   1082 H  HG21 . ILE A 1 72  ? 157.899 172.193 165.830 1.00 82.95  ? 83  ILE A HG21 1 
ATOM   1083 H  HG22 . ILE A 1 72  ? 157.737 172.970 167.206 1.00 83.32  ? 83  ILE A HG22 1 
ATOM   1084 H  HG23 . ILE A 1 72  ? 156.462 172.364 166.480 1.00 83.30  ? 83  ILE A HG23 1 
ATOM   1085 H  HD11 . ILE A 1 72  ? 159.043 173.759 162.838 1.00 82.70  ? 83  ILE A HD11 1 
ATOM   1086 H  HD12 . ILE A 1 72  ? 159.413 174.472 164.209 1.00 83.10  ? 83  ILE A HD12 1 
ATOM   1087 H  HD13 . ILE A 1 72  ? 159.222 172.896 164.160 1.00 82.43  ? 83  ILE A HD13 1 
ATOM   1088 N  N    . GLN A 1 73  ? 155.824 175.626 167.997 1.00 86.42  ? 84  GLN A N    1 
ATOM   1089 C  CA   . GLN A 1 73  ? 155.504 175.723 169.415 1.00 88.41  ? 84  GLN A CA   1 
ATOM   1090 C  C    . GLN A 1 73  ? 154.017 175.960 169.632 1.00 86.75  ? 84  GLN A C    1 
ATOM   1091 O  O    . GLN A 1 73  ? 153.434 175.402 170.566 1.00 85.11  ? 84  GLN A O    1 
ATOM   1092 C  CB   . GLN A 1 73  ? 156.320 176.842 170.063 1.00 86.32  ? 84  GLN A CB   1 
ATOM   1093 H  H    . GLN A 1 73  ? 156.346 176.243 167.702 1.00 85.49  ? 84  GLN A H    1 
ATOM   1094 H  HA   . GLN A 1 73  ? 155.742 174.888 169.850 1.00 86.67  ? 84  GLN A HA   1 
ATOM   1095 N  N    . ASP A 1 74  ? 153.389 176.769 168.778 1.00 81.07  ? 85  ASP A N    1 
ATOM   1096 C  CA   . ASP A 1 74  ? 151.965 177.046 168.927 1.00 80.54  ? 85  ASP A CA   1 
ATOM   1097 C  C    . ASP A 1 74  ? 151.139 175.784 168.721 1.00 78.01  ? 85  ASP A C    1 
ATOM   1098 O  O    . ASP A 1 74  ? 150.230 175.489 169.505 1.00 79.76  ? 85  ASP A O    1 
ATOM   1099 C  CB   . ASP A 1 74  ? 151.542 178.134 167.940 1.00 81.19  ? 85  ASP A CB   1 
ATOM   1100 C  CG   . ASP A 1 74  ? 152.150 179.483 168.267 1.00 85.14  ? 85  ASP A CG   1 
ATOM   1101 O  OD1  . ASP A 1 74  ? 152.860 179.582 169.289 1.00 82.17  ? 85  ASP A OD1  1 
ATOM   1102 O  OD2  . ASP A 1 74  ? 151.921 180.441 167.501 1.00 87.25  ? 85  ASP A OD2  1 
ATOM   1103 H  H    . ASP A 1 74  ? 153.762 177.162 168.111 1.00 81.25  ? 85  ASP A H    1 
ATOM   1104 H  HA   . ASP A 1 74  ? 151.796 177.371 169.824 1.00 81.88  ? 85  ASP A HA   1 
ATOM   1105 H  HB2  . ASP A 1 74  ? 151.829 177.882 167.048 1.00 81.00  ? 85  ASP A HB2  1 
ATOM   1106 H  HB3  . ASP A 1 74  ? 150.577 178.226 167.966 1.00 81.17  ? 85  ASP A HB3  1 
ATOM   1107 N  N    . GLN A 1 75  ? 151.441 175.022 167.667 1.00 82.29  ? 86  GLN A N    1 
ATOM   1108 C  CA   . GLN A 1 75  ? 150.706 173.781 167.440 1.00 86.70  ? 86  GLN A CA   1 
ATOM   1109 C  C    . GLN A 1 75  ? 150.935 172.790 168.576 1.00 85.34  ? 86  GLN A C    1 
ATOM   1110 O  O    . GLN A 1 75  ? 149.990 172.133 169.039 1.00 87.67  ? 86  GLN A O    1 
ATOM   1111 C  CB   . GLN A 1 75  ? 151.101 173.163 166.097 1.00 86.78  ? 86  GLN A CB   1 
ATOM   1112 C  CG   . GLN A 1 75  ? 150.945 174.087 164.899 1.00 85.66  ? 86  GLN A CG   1 
ATOM   1113 C  CD   . GLN A 1 75  ? 149.599 174.782 164.861 1.00 87.52  ? 86  GLN A CD   1 
ATOM   1114 O  OE1  . GLN A 1 75  ? 148.558 174.139 164.734 1.00 87.86  ? 86  GLN A OE1  1 
ATOM   1115 N  NE2  . GLN A 1 75  ? 149.616 176.108 164.952 1.00 86.17  ? 86  GLN A NE2  1 
ATOM   1116 H  H    . GLN A 1 75  ? 152.052 175.196 167.087 1.00 84.70  ? 86  GLN A H    1 
ATOM   1117 H  HA   . GLN A 1 75  ? 149.758 173.980 167.411 1.00 85.69  ? 86  GLN A HA   1 
ATOM   1118 H  HB2  . GLN A 1 75  ? 152.034 172.900 166.139 1.00 85.42  ? 86  GLN A HB2  1 
ATOM   1119 H  HB3  . GLN A 1 75  ? 150.548 172.382 165.940 1.00 85.01  ? 86  GLN A HB3  1 
ATOM   1120 H  HG2  . GLN A 1 75  ? 151.629 174.769 164.936 1.00 84.95  ? 86  GLN A HG2  1 
ATOM   1121 H  HG3  . GLN A 1 75  ? 151.038 173.570 164.084 1.00 84.65  ? 86  GLN A HG3  1 
ATOM   1122 H  HE21 . GLN A 1 75  ? 150.365 176.523 165.035 1.00 84.88  ? 86  GLN A HE21 1 
ATOM   1123 H  HE22 . GLN A 1 75  ? 148.880 176.549 164.933 1.00 85.20  ? 86  GLN A HE22 1 
ATOM   1124 N  N    . VAL A 1 76  ? 152.179 172.669 169.047 1.00 79.69  ? 87  VAL A N    1 
ATOM   1125 C  CA   . VAL A 1 76  ? 152.467 171.713 170.109 1.00 81.48  ? 87  VAL A CA   1 
ATOM   1126 C  C    . VAL A 1 76  ? 151.738 172.103 171.387 1.00 84.34  ? 87  VAL A C    1 
ATOM   1127 O  O    . VAL A 1 76  ? 151.187 171.248 172.089 1.00 86.65  ? 87  VAL A O    1 
ATOM   1128 C  CB   . VAL A 1 76  ? 153.984 171.606 170.335 1.00 81.44  ? 87  VAL A CB   1 
ATOM   1129 C  CG1  . VAL A 1 76  ? 154.273 170.845 171.623 1.00 79.70  ? 87  VAL A CG1  1 
ATOM   1130 C  CG2  . VAL A 1 76  ? 154.640 170.940 169.143 1.00 77.24  ? 87  VAL A CG2  1 
ATOM   1131 H  H    . VAL A 1 76  ? 152.857 173.122 168.773 1.00 80.95  ? 87  VAL A H    1 
ATOM   1132 H  HA   . VAL A 1 76  ? 152.147 170.837 169.842 1.00 81.18  ? 87  VAL A HA   1 
ATOM   1133 H  HB   . VAL A 1 76  ? 154.352 172.499 170.421 1.00 81.40  ? 87  VAL A HB   1 
ATOM   1134 H  HG11 . VAL A 1 76  ? 155.190 170.529 171.609 1.00 80.87  ? 87  VAL A HG11 1 
ATOM   1135 H  HG12 . VAL A 1 76  ? 154.142 171.440 172.377 1.00 80.66  ? 87  VAL A HG12 1 
ATOM   1136 H  HG13 . VAL A 1 76  ? 153.666 170.092 171.683 1.00 80.00  ? 87  VAL A HG13 1 
ATOM   1137 H  HG21 . VAL A 1 76  ? 155.007 170.083 169.415 1.00 80.06  ? 87  VAL A HG21 1 
ATOM   1138 H  HG22 . VAL A 1 76  ? 153.973 170.810 168.452 1.00 80.48  ? 87  VAL A HG22 1 
ATOM   1139 H  HG23 . VAL A 1 76  ? 155.347 171.517 168.812 1.00 80.31  ? 87  VAL A HG23 1 
ATOM   1140 N  N    . ASP A 1 77  ? 151.718 173.398 171.709 1.00 85.59  ? 88  ASP A N    1 
ATOM   1141 C  CA   . ASP A 1 77  ? 151.013 173.848 172.902 1.00 83.64  ? 88  ASP A CA   1 
ATOM   1142 C  C    . ASP A 1 77  ? 149.513 173.638 172.760 1.00 84.78  ? 88  ASP A C    1 
ATOM   1143 O  O    . ASP A 1 77  ? 148.840 173.250 173.723 1.00 84.16  ? 88  ASP A O    1 
ATOM   1144 C  CB   . ASP A 1 77  ? 151.328 175.319 173.168 1.00 81.53  ? 88  ASP A CB   1 
ATOM   1145 C  CG   . ASP A 1 77  ? 152.767 175.539 173.594 1.00 86.60  ? 88  ASP A CG   1 
ATOM   1146 O  OD1  . ASP A 1 77  ? 153.357 174.623 174.205 1.00 85.87  ? 88  ASP A OD1  1 
ATOM   1147 O  OD2  . ASP A 1 77  ? 153.309 176.629 173.314 1.00 88.49  ? 88  ASP A OD2  1 
ATOM   1148 H  H    . ASP A 1 77  ? 152.099 174.025 171.260 1.00 84.38  ? 88  ASP A H    1 
ATOM   1149 H  HA   . ASP A 1 77  ? 151.320 173.330 173.662 1.00 84.54  ? 88  ASP A HA   1 
ATOM   1150 H  HB2  . ASP A 1 77  ? 151.171 175.828 172.358 1.00 84.00  ? 88  ASP A HB2  1 
ATOM   1151 H  HB3  . ASP A 1 77  ? 150.751 175.639 173.880 1.00 84.55  ? 88  ASP A HB3  1 
ATOM   1152 N  N    . HIS A 1 78  ? 148.968 173.890 171.567 1.00 75.52  ? 89  HIS A N    1 
ATOM   1153 C  CA   . HIS A 1 78  ? 147.542 173.684 171.350 1.00 74.22  ? 89  HIS A CA   1 
ATOM   1154 C  C    . HIS A 1 78  ? 147.163 172.224 171.557 1.00 72.99  ? 89  HIS A C    1 
ATOM   1155 O  O    . HIS A 1 78  ? 146.133 171.924 172.171 1.00 70.18  ? 89  HIS A O    1 
ATOM   1156 C  CB   . HIS A 1 78  ? 147.155 174.142 169.944 1.00 69.19  ? 89  HIS A CB   1 
ATOM   1157 C  CG   . HIS A 1 78  ? 145.687 174.058 169.662 1.00 67.64  ? 89  HIS A CG   1 
ATOM   1158 N  ND1  . HIS A 1 78  ? 145.071 172.894 169.254 1.00 67.40  ? 89  HIS A ND1  1 
ATOM   1159 C  CD2  . HIS A 1 78  ? 144.714 174.997 169.721 1.00 68.89  ? 89  HIS A CD2  1 
ATOM   1160 C  CE1  . HIS A 1 78  ? 143.781 173.119 169.079 1.00 72.45  ? 89  HIS A CE1  1 
ATOM   1161 N  NE2  . HIS A 1 78  ? 143.538 174.387 169.356 1.00 73.74  ? 89  HIS A NE2  1 
ATOM   1162 H  H    . HIS A 1 78  ? 149.399 174.176 170.879 1.00 73.73  ? 89  HIS A H    1 
ATOM   1163 H  HA   . HIS A 1 78  ? 147.045 174.218 171.989 1.00 73.28  ? 89  HIS A HA   1 
ATOM   1164 H  HB2  . HIS A 1 78  ? 147.425 175.067 169.831 1.00 72.26  ? 89  HIS A HB2  1 
ATOM   1165 H  HB3  . HIS A 1 78  ? 147.614 173.584 169.296 1.00 72.57  ? 89  HIS A HB3  1 
ATOM   1166 H  HD2  . HIS A 1 78  ? 144.821 175.889 169.965 1.00 71.60  ? 89  HIS A HD2  1 
ATOM   1167 H  HE1  . HIS A 1 78  ? 143.151 172.492 168.807 1.00 72.56  ? 89  HIS A HE1  1 
ATOM   1168 H  HE2  . HIS A 1 78  ? 142.769 174.770 169.314 1.00 72.59  ? 89  HIS A HE2  1 
ATOM   1169 N  N    . LEU A 1 79  ? 147.981 171.300 171.048 1.00 78.46  ? 90  LEU A N    1 
ATOM   1170 C  CA   . LEU A 1 79  ? 147.675 169.885 171.240 1.00 79.05  ? 90  LEU A CA   1 
ATOM   1171 C  C    . LEU A 1 79  ? 147.888 169.455 172.687 1.00 84.51  ? 90  LEU A C    1 
ATOM   1172 O  O    . LEU A 1 79  ? 147.130 168.630 173.209 1.00 85.14  ? 90  LEU A O    1 
ATOM   1173 C  CB   . LEU A 1 79  ? 148.507 169.021 170.294 1.00 76.84  ? 90  LEU A CB   1 
ATOM   1174 C  CG   . LEU A 1 79  ? 147.891 168.842 168.905 1.00 81.74  ? 90  LEU A CG   1 
ATOM   1175 C  CD1  . LEU A 1 79  ? 148.060 170.092 168.056 1.00 80.66  ? 90  LEU A CD1  1 
ATOM   1176 C  CD2  . LEU A 1 79  ? 148.476 167.617 168.212 1.00 76.96  ? 90  LEU A CD2  1 
ATOM   1177 H  HA   . LEU A 1 79  ? 146.740 169.740 171.028 1.00 78.62  ? 90  LEU A HA   1 
ATOM   1178 H  HB2  . LEU A 1 79  ? 149.377 169.436 170.179 1.00 78.80  ? 90  LEU A HB2  1 
ATOM   1179 H  HB3  . LEU A 1 79  ? 148.614 168.144 170.691 1.00 78.68  ? 90  LEU A HB3  1 
ATOM   1180 H  HG   . LEU A 1 79  ? 146.939 168.688 169.009 1.00 79.32  ? 90  LEU A HG   1 
ATOM   1181 H  HD11 . LEU A 1 79  ? 147.361 170.107 167.386 1.00 79.00  ? 90  LEU A HD11 1 
ATOM   1182 H  HD12 . LEU A 1 79  ? 147.983 170.873 168.622 1.00 79.68  ? 90  LEU A HD12 1 
ATOM   1183 H  HD13 . LEU A 1 79  ? 148.933 170.076 167.632 1.00 79.22  ? 90  LEU A HD13 1 
ATOM   1184 H  HD21 . LEU A 1 79  ? 147.843 167.303 167.549 1.00 78.55  ? 90  LEU A HD21 1 
ATOM   1185 H  HD22 . LEU A 1 79  ? 149.313 167.859 167.787 1.00 79.00  ? 90  LEU A HD22 1 
ATOM   1186 H  HD23 . LEU A 1 79  ? 148.625 166.921 168.870 1.00 79.15  ? 90  LEU A HD23 1 
ATOM   1187 N  N    . LEU A 1 80  ? 148.911 169.995 173.353 1.00 91.32  ? 91  LEU A N    1 
ATOM   1188 C  CA   . LEU A 1 80  ? 149.112 169.672 174.761 1.00 90.06  ? 91  LEU A CA   1 
ATOM   1189 C  C    . LEU A 1 80  ? 147.921 170.123 175.595 1.00 88.52  ? 91  LEU A C    1 
ATOM   1190 O  O    . LEU A 1 80  ? 147.497 169.420 176.519 1.00 86.95  ? 91  LEU A O    1 
ATOM   1191 C  CB   . LEU A 1 80  ? 150.402 170.312 175.270 1.00 89.78  ? 91  LEU A CB   1 
ATOM   1192 C  CG   . LEU A 1 80  ? 151.693 169.636 174.802 1.00 92.05  ? 91  LEU A CG   1 
ATOM   1193 C  CD1  . LEU A 1 80  ? 152.879 170.575 174.954 1.00 90.24  ? 91  LEU A CD1  1 
ATOM   1194 C  CD2  . LEU A 1 80  ? 151.930 168.342 175.569 1.00 91.07  ? 91  LEU A CD2  1 
ATOM   1195 H  H    . LEU A 1 80  ? 149.488 170.538 173.020 1.00 88.31  ? 91  LEU A H    1 
ATOM   1196 H  HA   . LEU A 1 80  ? 149.194 168.710 174.854 1.00 88.66  ? 91  LEU A HA   1 
ATOM   1197 H  HB2  . LEU A 1 80  ? 150.428 171.233 174.966 1.00 88.20  ? 91  LEU A HB2  1 
ATOM   1198 H  HB3  . LEU A 1 80  ? 150.394 170.290 176.239 1.00 88.72  ? 91  LEU A HB3  1 
ATOM   1199 H  HG   . LEU A 1 80  ? 151.607 169.412 173.862 1.00 88.86  ? 91  LEU A HG   1 
ATOM   1200 H  HD11 . LEU A 1 80  ? 153.680 170.123 174.646 1.00 88.72  ? 91  LEU A HD11 1 
ATOM   1201 H  HD12 . LEU A 1 80  ? 152.722 171.369 174.420 1.00 88.43  ? 91  LEU A HD12 1 
ATOM   1202 H  HD13 . LEU A 1 80  ? 152.974 170.818 175.889 1.00 88.70  ? 91  LEU A HD13 1 
ATOM   1203 H  HD21 . LEU A 1 80  ? 152.768 167.952 175.275 1.00 88.86  ? 91  LEU A HD21 1 
ATOM   1204 H  HD22 . LEU A 1 80  ? 151.972 168.540 176.518 1.00 89.30  ? 91  LEU A HD22 1 
ATOM   1205 H  HD23 . LEU A 1 80  ? 151.200 167.729 175.391 1.00 88.80  ? 91  LEU A HD23 1 
ATOM   1206 N  N    . THR A 1 81  ? 147.365 171.294 175.278 1.00 85.01  ? 92  THR A N    1 
ATOM   1207 C  CA   . THR A 1 81  ? 146.149 171.736 175.949 1.00 87.03  ? 92  THR A CA   1 
ATOM   1208 C  C    . THR A 1 81  ? 145.027 170.721 175.776 1.00 86.21  ? 92  THR A C    1 
ATOM   1209 O  O    . THR A 1 81  ? 144.131 170.633 176.624 1.00 87.60  ? 92  THR A O    1 
ATOM   1210 C  CB   . THR A 1 81  ? 145.720 173.101 175.409 1.00 84.36  ? 92  THR A CB   1 
ATOM   1211 O  OG1  . THR A 1 81  ? 146.639 174.105 175.858 1.00 82.42  ? 92  THR A OG1  1 
ATOM   1212 C  CG2  . THR A 1 81  ? 144.318 173.456 175.881 1.00 85.88  ? 92  THR A CG2  1 
ATOM   1213 H  H    . THR A 1 81  ? 147.669 171.842 174.688 1.00 84.85  ? 92  THR A H    1 
ATOM   1214 H  HA   . THR A 1 81  ? 146.326 171.830 176.898 1.00 85.87  ? 92  THR A HA   1 
ATOM   1215 H  HB   . THR A 1 81  ? 145.719 173.077 174.439 1.00 84.48  ? 92  THR A HB   1 
ATOM   1216 H  HG1  . THR A 1 81  ? 146.415 174.856 175.556 1.00 84.76  ? 92  THR A HG1  1 
ATOM   1217 H  HG21 . THR A 1 81  ? 144.176 174.412 175.798 1.00 85.18  ? 92  THR A HG21 1 
ATOM   1218 H  HG22 . THR A 1 81  ? 143.656 172.993 175.344 1.00 85.11  ? 92  THR A HG22 1 
ATOM   1219 H  HG23 . THR A 1 81  ? 144.207 173.203 176.811 1.00 85.44  ? 92  THR A HG23 1 
ATOM   1220 N  N    . LEU A 1 82  ? 145.062 169.946 174.695 1.00 82.11  ? 93  LEU A N    1 
ATOM   1221 C  CA   . LEU A 1 82  ? 144.097 168.886 174.449 1.00 81.95  ? 93  LEU A CA   1 
ATOM   1222 C  C    . LEU A 1 82  ? 144.533 167.552 175.042 1.00 82.02  ? 93  LEU A C    1 
ATOM   1223 O  O    . LEU A 1 82  ? 143.938 166.519 174.719 1.00 85.86  ? 93  LEU A O    1 
ATOM   1224 C  CB   . LEU A 1 82  ? 143.863 168.731 172.944 1.00 82.28  ? 93  LEU A CB   1 
ATOM   1225 C  CG   . LEU A 1 82  ? 143.268 169.946 172.230 1.00 85.29  ? 93  LEU A CG   1 
ATOM   1226 C  CD1  . LEU A 1 82  ? 143.112 169.657 170.749 1.00 83.74  ? 93  LEU A CD1  1 
ATOM   1227 C  CD2  . LEU A 1 82  ? 141.932 170.344 172.843 1.00 81.95  ? 93  LEU A CD2  1 
ATOM   1228 H  H    . LEU A 1 82  ? 145.654 170.019 174.075 1.00 82.15  ? 93  LEU A H    1 
ATOM   1229 H  HA   . LEU A 1 82  ? 143.254 169.127 174.861 1.00 82.13  ? 93  LEU A HA   1 
ATOM   1230 H  HB2  . LEU A 1 82  ? 144.714 168.537 172.522 1.00 82.39  ? 93  LEU A HB2  1 
ATOM   1231 H  HB3  . LEU A 1 82  ? 143.256 167.987 172.804 1.00 81.82  ? 93  LEU A HB3  1 
ATOM   1232 H  HG   . LEU A 1 82  ? 143.875 170.696 172.326 1.00 82.35  ? 93  LEU A HG   1 
ATOM   1233 H  HD11 . LEU A 1 82  ? 142.636 170.391 170.331 1.00 81.82  ? 93  LEU A HD11 1 
ATOM   1234 H  HD12 . LEU A 1 82  ? 143.993 169.564 170.352 1.00 81.88  ? 93  LEU A HD12 1 
ATOM   1235 H  HD13 . LEU A 1 82  ? 142.613 168.833 170.641 1.00 82.11  ? 93  LEU A HD13 1 
ATOM   1236 H  HD21 . LEU A 1 82  ? 141.517 171.018 172.284 1.00 82.05  ? 93  LEU A HD21 1 
ATOM   1237 H  HD22 . LEU A 1 82  ? 141.364 169.559 172.894 1.00 82.06  ? 93  LEU A HD22 1 
ATOM   1238 H  HD23 . LEU A 1 82  ? 142.085 170.699 173.732 1.00 81.93  ? 93  LEU A HD23 1 
ATOM   1239 N  N    . LYS A 1 83  ? 145.560 167.550 175.892 1.00 73.70  ? 94  LYS A N    1 
ATOM   1240 C  CA   . LYS A 1 83  ? 146.068 166.349 176.544 1.00 73.50  ? 94  LYS A CA   1 
ATOM   1241 C  C    . LYS A 1 83  ? 146.700 165.373 175.562 1.00 72.18  ? 94  LYS A C    1 
ATOM   1242 O  O    . LYS A 1 83  ? 146.844 164.187 175.871 1.00 73.57  ? 94  LYS A O    1 
ATOM   1243 C  CB   . LYS A 1 83  ? 144.960 165.640 177.333 1.00 79.07  ? 94  LYS A CB   1 
ATOM   1244 C  CG   . LYS A 1 83  ? 144.071 166.568 178.156 1.00 78.79  ? 94  LYS A CG   1 
ATOM   1245 C  CD   . LYS A 1 83  ? 144.877 167.556 178.992 1.00 79.18  ? 94  LYS A CD   1 
ATOM   1246 C  CE   . LYS A 1 83  ? 145.846 166.850 179.933 1.00 76.54  ? 94  LYS A CE   1 
ATOM   1247 N  NZ   . LYS A 1 83  ? 145.167 165.830 180.779 1.00 77.60  ? 94  LYS A NZ   1 
ATOM   1248 H  H    . LYS A 1 83  ? 145.993 168.259 176.113 1.00 76.56  ? 94  LYS A H    1 
ATOM   1249 H  HA   . LYS A 1 83  ? 146.756 166.612 177.175 1.00 76.06  ? 94  LYS A HA   1 
ATOM   1250 H  HB2  . LYS A 1 83  ? 144.388 165.167 176.709 1.00 77.03  ? 94  LYS A HB2  1 
ATOM   1251 H  HB3  . LYS A 1 83  ? 145.369 165.005 177.943 1.00 76.70  ? 94  LYS A HB3  1 
ATOM   1252 H  HG2  . LYS A 1 83  ? 143.500 167.075 177.558 1.00 76.48  ? 94  LYS A HG2  1 
ATOM   1253 H  HG3  . LYS A 1 83  ? 143.528 166.035 178.759 1.00 76.64  ? 94  LYS A HG3  1 
ATOM   1254 H  HD2  . LYS A 1 83  ? 145.388 168.138 178.408 1.00 76.98  ? 94  LYS A HD2  1 
ATOM   1255 H  HD3  . LYS A 1 83  ? 144.266 168.081 179.532 1.00 76.61  ? 94  LYS A HD3  1 
ATOM   1256 H  HE2  . LYS A 1 83  ? 146.531 166.402 179.413 1.00 76.13  ? 94  LYS A HE2  1 
ATOM   1257 H  HE3  . LYS A 1 83  ? 146.251 167.507 180.520 1.00 76.10  ? 94  LYS A HE3  1 
ATOM   1258 H  HZ1  . LYS A 1 83  ? 144.507 166.209 181.241 1.00 76.32  ? 94  LYS A HZ1  1 
ATOM   1259 H  HZ2  . LYS A 1 83  ? 144.829 165.186 180.267 1.00 76.68  ? 94  LYS A HZ2  1 
ATOM   1260 H  HZ3  . LYS A 1 83  ? 145.750 165.472 181.348 1.00 76.34  ? 94  LYS A HZ3  1 
ATOM   1261 N  N    . VAL A 1 84  ? 147.087 165.847 174.385 1.00 66.41  ? 95  VAL A N    1 
ATOM   1262 C  CA   . VAL A 1 84  ? 147.677 164.988 173.366 1.00 65.84  ? 95  VAL A CA   1 
ATOM   1263 C  C    . VAL A 1 84  ? 149.162 164.808 173.645 1.00 74.31  ? 95  VAL A C    1 
ATOM   1264 O  O    . VAL A 1 84  ? 149.859 165.749 174.044 1.00 80.95  ? 95  VAL A O    1 
ATOM   1265 C  CB   . VAL A 1 84  ? 147.444 165.578 171.965 1.00 68.58  ? 95  VAL A CB   1 
ATOM   1266 C  CG1  . VAL A 1 84  ? 148.032 164.668 170.904 1.00 71.80  ? 95  VAL A CG1  1 
ATOM   1267 C  CG2  . VAL A 1 84  ? 145.958 165.793 171.724 1.00 74.05  ? 95  VAL A CG2  1 
ATOM   1268 H  H    . VAL A 1 84  ? 147.014 166.671 174.144 1.00 72.99  ? 95  VAL A H    1 
ATOM   1269 H  HA   . VAL A 1 84  ? 147.258 164.115 173.403 1.00 72.07  ? 95  VAL A HA   1 
ATOM   1270 H  HB   . VAL A 1 84  ? 147.889 166.436 171.907 1.00 72.71  ? 95  VAL A HB   1 
ATOM   1271 H  HG11 . VAL A 1 84  ? 147.772 164.997 170.031 1.00 73.22  ? 95  VAL A HG11 1 
ATOM   1272 H  HG12 . VAL A 1 84  ? 148.999 164.666 170.981 1.00 72.81  ? 95  VAL A HG12 1 
ATOM   1273 H  HG13 . VAL A 1 84  ? 147.690 163.769 171.035 1.00 72.77  ? 95  VAL A HG13 1 
ATOM   1274 H  HG21 . VAL A 1 84  ? 145.821 166.066 170.805 1.00 73.79  ? 95  VAL A HG21 1 
ATOM   1275 H  HG22 . VAL A 1 84  ? 145.488 164.961 171.897 1.00 73.47  ? 95  VAL A HG22 1 
ATOM   1276 H  HG23 . VAL A 1 84  ? 145.640 166.482 172.328 1.00 73.45  ? 95  VAL A HG23 1 
ATOM   1277 N  N    . ARG A 1 85  ? 149.651 163.590 173.425 1.00 73.58  ? 96  ARG A N    1 
ATOM   1278 C  CA   . ARG A 1 85  ? 151.070 163.280 173.577 1.00 74.06  ? 96  ARG A CA   1 
ATOM   1279 C  C    . ARG A 1 85  ? 151.812 163.840 172.371 1.00 65.85  ? 96  ARG A C    1 
ATOM   1280 O  O    . ARG A 1 85  ? 151.894 163.195 171.322 1.00 68.29  ? 96  ARG A O    1 
ATOM   1281 C  CB   . ARG A 1 85  ? 151.282 161.775 173.704 1.00 76.49  ? 96  ARG A CB   1 
ATOM   1282 C  CG   . ARG A 1 85  ? 150.422 161.102 174.764 1.00 71.43  ? 96  ARG A CG   1 
ATOM   1283 C  CD   . ARG A 1 85  ? 150.261 161.971 175.996 1.00 67.28  ? 96  ARG A CD   1 
ATOM   1284 N  NE   . ARG A 1 85  ? 149.894 161.190 177.170 1.00 70.24  ? 96  ARG A NE   1 
ATOM   1285 C  CZ   . ARG A 1 85  ? 149.459 161.711 178.308 1.00 73.87  ? 96  ARG A CZ   1 
ATOM   1286 N  NH1  . ARG A 1 85  ? 149.320 163.018 178.462 1.00 74.71  ? 96  ARG A NH1  1 
ATOM   1287 N  NH2  . ARG A 1 85  ? 149.154 160.901 179.317 1.00 75.18  ? 96  ARG A NH2  1 
ATOM   1288 H  H    . ARG A 1 85  ? 149.173 162.917 173.187 1.00 71.62  ? 96  ARG A H    1 
ATOM   1289 H  HA   . ARG A 1 85  ? 151.414 163.715 174.373 1.00 72.53  ? 96  ARG A HA   1 
ATOM   1290 H  HB2  . ARG A 1 85  ? 151.073 161.358 172.853 1.00 72.73  ? 96  ARG A HB2  1 
ATOM   1291 H  HB3  . ARG A 1 85  ? 152.211 161.609 173.930 1.00 72.34  ? 96  ARG A HB3  1 
ATOM   1292 H  HG2  . ARG A 1 85  ? 149.542 160.929 174.398 1.00 71.48  ? 96  ARG A HG2  1 
ATOM   1293 H  HG3  . ARG A 1 85  ? 150.842 160.270 175.034 1.00 71.57  ? 96  ARG A HG3  1 
ATOM   1294 H  HD2  . ARG A 1 85  ? 151.102 162.418 176.184 1.00 71.45  ? 96  ARG A HD2  1 
ATOM   1295 H  HD3  . ARG A 1 85  ? 149.562 162.623 175.836 1.00 70.99  ? 96  ARG A HD3  1 
ATOM   1296 H  HE   . ARG A 1 85  ? 149.991 160.337 177.129 1.00 72.00  ? 96  ARG A HE   1 
ATOM   1297 H  HH11 . ARG A 1 85  ? 149.036 163.333 179.210 1.00 72.21  ? 96  ARG A HH11 1 
ATOM   1298 H  HH12 . ARG A 1 85  ? 149.514 163.553 177.817 1.00 72.16  ? 96  ARG A HH12 1 
ATOM   1299 H  HH21 . ARG A 1 85  ? 149.241 160.050 179.225 1.00 72.09  ? 96  ARG A HH21 1 
ATOM   1300 H  HH22 . ARG A 1 85  ? 148.871 161.227 180.060 1.00 72.24  ? 96  ARG A HH22 1 
ATOM   1301 N  N    . VAL A 1 86  ? 152.357 165.045 172.517 1.00 62.23  ? 97  VAL A N    1 
ATOM   1302 C  CA   . VAL A 1 86  ? 153.056 165.727 171.436 1.00 63.19  ? 97  VAL A CA   1 
ATOM   1303 C  C    . VAL A 1 86  ? 154.457 166.096 171.898 1.00 76.15  ? 97  VAL A C    1 
ATOM   1304 O  O    . VAL A 1 86  ? 154.703 166.331 173.085 1.00 78.66  ? 97  VAL A O    1 
ATOM   1305 C  CB   . VAL A 1 86  ? 152.296 166.987 170.971 1.00 65.29  ? 97  VAL A CB   1 
ATOM   1306 C  CG1  . VAL A 1 86  ? 153.108 167.755 169.934 1.00 68.48  ? 97  VAL A CG1  1 
ATOM   1307 C  CG2  . VAL A 1 86  ? 150.932 166.610 170.417 1.00 71.76  ? 97  VAL A CG2  1 
ATOM   1308 H  H    . VAL A 1 86  ? 152.331 165.497 173.249 1.00 70.79  ? 97  VAL A H    1 
ATOM   1309 H  HA   . VAL A 1 86  ? 153.136 165.128 170.679 1.00 70.23  ? 97  VAL A HA   1 
ATOM   1310 H  HB   . VAL A 1 86  ? 152.156 167.571 171.733 1.00 71.19  ? 97  VAL A HB   1 
ATOM   1311 H  HG11 . VAL A 1 86  ? 152.538 168.419 169.513 1.00 71.90  ? 97  VAL A HG11 1 
ATOM   1312 H  HG12 . VAL A 1 86  ? 153.851 168.197 170.374 1.00 70.60  ? 97  VAL A HG12 1 
ATOM   1313 H  HG13 . VAL A 1 86  ? 153.439 167.135 169.266 1.00 71.43  ? 97  VAL A HG13 1 
ATOM   1314 H  HG21 . VAL A 1 86  ? 150.616 167.328 169.848 1.00 71.52  ? 97  VAL A HG21 1 
ATOM   1315 H  HG22 . VAL A 1 86  ? 151.013 165.791 169.904 1.00 71.59  ? 97  VAL A HG22 1 
ATOM   1316 H  HG23 . VAL A 1 86  ? 150.319 166.478 171.156 1.00 71.97  ? 97  VAL A HG23 1 
ATOM   1317 N  N    . SER A 1 87  ? 155.380 166.147 170.940 1.00 87.12  ? 98  SER A N    1 
ATOM   1318 C  CA   . SER A 1 87  ? 156.750 166.569 171.185 1.00 86.18  ? 98  SER A CA   1 
ATOM   1319 C  C    . SER A 1 87  ? 157.155 167.594 170.136 1.00 74.48  ? 98  SER A C    1 
ATOM   1320 O  O    . SER A 1 87  ? 156.624 167.601 169.025 1.00 77.58  ? 98  SER A O    1 
ATOM   1321 C  CB   . SER A 1 87  ? 157.718 165.380 171.156 1.00 86.50  ? 98  SER A CB   1 
ATOM   1322 O  OG   . SER A 1 87  ? 157.910 164.914 169.831 1.00 88.58  ? 98  SER A OG   1 
ATOM   1323 H  H    . SER A 1 87  ? 155.229 165.937 170.121 1.00 82.63  ? 98  SER A H    1 
ATOM   1324 H  HA   . SER A 1 87  ? 156.813 166.989 172.056 1.00 83.04  ? 98  SER A HA   1 
ATOM   1325 H  HB2  . SER A 1 87  ? 158.570 165.665 171.517 1.00 82.83  ? 98  SER A HB2  1 
ATOM   1326 H  HB3  . SER A 1 87  ? 157.355 164.663 171.698 1.00 82.47  ? 98  SER A HB3  1 
ATOM   1327 H  HG   . SER A 1 87  ? 158.419 164.246 169.835 1.00 83.06  ? 98  SER A HG   1 
ATOM   1328 N  N    . SER A 1 88  ? 158.095 168.463 170.502 1.00 64.50  ? 99  SER A N    1 
ATOM   1329 C  CA   . SER A 1 88  ? 158.589 169.527 169.628 1.00 60.11  ? 99  SER A CA   1 
ATOM   1330 C  C    . SER A 1 88  ? 160.114 169.460 169.580 1.00 66.82  ? 99  SER A C    1 
ATOM   1331 O  O    . SER A 1 88  ? 160.790 169.975 170.473 1.00 77.36  ? 99  SER A O    1 
ATOM   1332 C  CB   . SER A 1 88  ? 158.119 170.887 170.121 1.00 69.93  ? 99  SER A CB   1 
ATOM   1333 O  OG   . SER A 1 88  ? 158.310 171.016 171.514 1.00 73.14  ? 99  SER A OG   1 
ATOM   1334 H  H    . SER A 1 88  ? 158.466 168.461 171.275 1.00 71.31  ? 99  SER A H    1 
ATOM   1335 H  HA   . SER A 1 88  ? 158.249 169.395 168.728 1.00 68.84  ? 99  SER A HA   1 
ATOM   1336 H  HB2  . SER A 1 88  ? 158.621 171.583 169.665 1.00 70.67  ? 99  SER A HB2  1 
ATOM   1337 H  HB3  . SER A 1 88  ? 157.175 170.981 169.925 1.00 70.72  ? 99  SER A HB3  1 
ATOM   1338 H  HG   . SER A 1 88  ? 159.122 170.889 171.699 1.00 70.84  ? 99  SER A HG   1 
ATOM   1339 N  N    . LEU A 1 89  ? 160.658 168.834 168.536 1.00 73.42  ? 100 LEU A N    1 
ATOM   1340 C  CA   . LEU A 1 89  ? 162.103 168.747 168.357 1.00 78.57  ? 100 LEU A CA   1 
ATOM   1341 C  C    . LEU A 1 89  ? 162.562 169.945 167.534 1.00 76.53  ? 100 LEU A C    1 
ATOM   1342 O  O    . LEU A 1 89  ? 162.326 170.001 166.324 1.00 80.20  ? 100 LEU A O    1 
ATOM   1343 C  CB   . LEU A 1 89  ? 162.487 167.435 167.677 1.00 81.49  ? 100 LEU A CB   1 
ATOM   1344 C  CG   . LEU A 1 89  ? 162.516 166.170 168.542 1.00 83.26  ? 100 LEU A CG   1 
ATOM   1345 C  CD1  . LEU A 1 89  ? 162.853 164.948 167.702 1.00 85.65  ? 100 LEU A CD1  1 
ATOM   1346 C  CD2  . LEU A 1 89  ? 163.522 166.315 169.670 1.00 80.38  ? 100 LEU A CD2  1 
ATOM   1347 H  H    . LEU A 1 89  ? 160.206 168.448 167.915 1.00 79.62  ? 100 LEU A H    1 
ATOM   1348 H  HA   . LEU A 1 89  ? 162.538 168.791 169.223 1.00 80.11  ? 100 LEU A HA   1 
ATOM   1349 H  HB2  . LEU A 1 89  ? 161.853 167.273 166.963 1.00 80.71  ? 100 LEU A HB2  1 
ATOM   1350 H  HB3  . LEU A 1 89  ? 163.374 167.539 167.297 1.00 80.39  ? 100 LEU A HB3  1 
ATOM   1351 H  HG   . LEU A 1 89  ? 161.640 166.032 168.938 1.00 80.55  ? 100 LEU A HG   1 
ATOM   1352 H  HD11 . LEU A 1 89  ? 162.724 164.150 168.238 1.00 81.21  ? 100 LEU A HD11 1 
ATOM   1353 H  HD12 . LEU A 1 89  ? 162.269 164.925 166.930 1.00 80.84  ? 100 LEU A HD12 1 
ATOM   1354 H  HD13 . LEU A 1 89  ? 163.777 165.007 167.415 1.00 81.32  ? 100 LEU A HD13 1 
ATOM   1355 H  HD21 . LEU A 1 89  ? 163.622 165.461 170.118 1.00 79.77  ? 100 LEU A HD21 1 
ATOM   1356 H  HD22 . LEU A 1 89  ? 164.373 166.594 169.295 1.00 80.39  ? 100 LEU A HD22 1 
ATOM   1357 H  HD23 . LEU A 1 89  ? 163.203 166.982 170.297 1.00 80.15  ? 100 LEU A HD23 1 
ATOM   1358 N  N    . ASN A 1 90  ? 163.208 170.907 168.191 1.00 74.26  ? 101 ASN A N    1 
ATOM   1359 C  CA   . ASN A 1 90  ? 163.717 172.090 167.513 1.00 77.73  ? 101 ASN A CA   1 
ATOM   1360 C  C    . ASN A 1 90  ? 164.945 172.598 168.253 1.00 80.78  ? 101 ASN A C    1 
ATOM   1361 O  O    . ASN A 1 90  ? 165.195 172.236 169.405 1.00 82.27  ? 101 ASN A O    1 
ATOM   1362 C  CB   . ASN A 1 90  ? 162.664 173.202 167.428 1.00 82.35  ? 101 ASN A CB   1 
ATOM   1363 C  CG   . ASN A 1 90  ? 161.282 172.678 167.090 1.00 85.35  ? 101 ASN A CG   1 
ATOM   1364 O  OD1  . ASN A 1 90  ? 161.026 172.247 165.966 1.00 85.25  ? 101 ASN A OD1  1 
ATOM   1365 N  ND2  . ASN A 1 90  ? 160.385 172.709 168.067 1.00 82.19  ? 101 ASN A ND2  1 
ATOM   1366 H  H    . ASN A 1 90  ? 163.361 170.896 169.036 1.00 80.00  ? 101 ASN A H    1 
ATOM   1367 H  HA   . ASN A 1 90  ? 163.982 171.854 166.611 1.00 80.79  ? 101 ASN A HA   1 
ATOM   1368 H  HB2  . ASN A 1 90  ? 162.613 173.656 168.283 1.00 80.95  ? 101 ASN A HB2  1 
ATOM   1369 H  HB3  . ASN A 1 90  ? 162.925 173.826 166.733 1.00 81.08  ? 101 ASN A HB3  1 
ATOM   1370 H  HD21 . ASN A 1 90  ? 160.601 173.016 168.841 1.00 81.02  ? 101 ASN A HD21 1 
ATOM   1371 H  HD22 . ASN A 1 90  ? 159.587 172.422 167.926 1.00 80.65  ? 101 ASN A HD22 1 
ATOM   1372 N  N    . SER A 1 91  ? 165.715 173.449 167.568 1.00 96.67  ? 102 SER A N    1 
ATOM   1373 C  CA   . SER A 1 91  ? 166.899 174.034 168.187 1.00 100.76 ? 102 SER A CA   1 
ATOM   1374 C  C    . SER A 1 91  ? 166.538 174.836 169.429 1.00 98.71  ? 102 SER A C    1 
ATOM   1375 O  O    . SER A 1 91  ? 167.344 174.935 170.361 1.00 98.96  ? 102 SER A O    1 
ATOM   1376 C  CB   . SER A 1 91  ? 167.636 174.919 167.181 1.00 99.39  ? 102 SER A CB   1 
ATOM   1377 O  OG   . SER A 1 91  ? 166.762 175.874 166.605 1.00 99.35  ? 102 SER A OG   1 
ATOM   1378 H  H    . SER A 1 91  ? 165.574 173.698 166.757 1.00 96.84  ? 102 SER A H    1 
ATOM   1379 H  HA   . SER A 1 91  ? 167.501 173.321 168.454 1.00 97.96  ? 102 SER A HA   1 
ATOM   1380 H  HB2  . SER A 1 91  ? 168.355 175.385 167.638 1.00 97.85  ? 102 SER A HB2  1 
ATOM   1381 H  HB3  . SER A 1 91  ? 168.001 174.361 166.476 1.00 97.66  ? 102 SER A HB3  1 
ATOM   1382 H  HG   . SER A 1 91  ? 167.182 176.357 166.061 1.00 97.89  ? 102 SER A HG   1 
ATOM   1383 N  N    . LYS A 1 92  ? 165.336 175.416 169.460 1.00 87.78  ? 103 LYS A N    1 
ATOM   1384 C  CA   . LYS A 1 92  ? 164.879 176.111 170.659 1.00 91.27  ? 103 LYS A CA   1 
ATOM   1385 C  C    . LYS A 1 92  ? 164.877 175.186 171.869 1.00 91.17  ? 103 LYS A C    1 
ATOM   1386 O  O    . LYS A 1 92  ? 165.086 175.640 173.000 1.00 90.25  ? 103 LYS A O    1 
ATOM   1387 C  CB   . LYS A 1 92  ? 163.482 176.686 170.423 1.00 89.84  ? 103 LYS A CB   1 
ATOM   1388 C  CG   . LYS A 1 92  ? 163.005 177.646 171.503 1.00 90.06  ? 103 LYS A CG   1 
ATOM   1389 C  CD   . LYS A 1 92  ? 161.626 178.218 171.184 1.00 87.51  ? 103 LYS A CD   1 
ATOM   1390 C  CE   . LYS A 1 92  ? 160.542 177.146 171.172 1.00 85.39  ? 103 LYS A CE   1 
ATOM   1391 N  NZ   . LYS A 1 92  ? 160.517 176.338 172.422 1.00 87.50  ? 103 LYS A NZ   1 
ATOM   1392 H  H    . LYS A 1 92  ? 164.774 175.421 168.808 1.00 87.80  ? 103 LYS A H    1 
ATOM   1393 H  HA   . LYS A 1 92  ? 165.481 176.848 170.846 1.00 88.91  ? 103 LYS A HA   1 
ATOM   1394 H  HB2  . LYS A 1 92  ? 163.483 177.168 169.580 1.00 87.89  ? 103 LYS A HB2  1 
ATOM   1395 H  HB3  . LYS A 1 92  ? 162.852 175.951 170.378 1.00 88.25  ? 103 LYS A HB3  1 
ATOM   1396 H  HG2  . LYS A 1 92  ? 162.953 177.175 172.349 1.00 88.57  ? 103 LYS A HG2  1 
ATOM   1397 H  HG3  . LYS A 1 92  ? 163.630 178.385 171.570 1.00 88.17  ? 103 LYS A HG3  1 
ATOM   1398 H  HD2  . LYS A 1 92  ? 161.392 178.875 171.857 1.00 88.30  ? 103 LYS A HD2  1 
ATOM   1399 H  HD3  . LYS A 1 92  ? 161.650 178.632 170.307 1.00 87.34  ? 103 LYS A HD3  1 
ATOM   1400 H  HE2  . LYS A 1 92  ? 159.677 177.575 171.077 1.00 87.03  ? 103 LYS A HE2  1 
ATOM   1401 H  HE3  . LYS A 1 92  ? 160.695 176.545 170.426 1.00 87.62  ? 103 LYS A HE3  1 
ATOM   1402 H  HZ1  . LYS A 1 92  ? 160.422 176.872 173.128 1.00 87.83  ? 103 LYS A HZ1  1 
ATOM   1403 H  HZ2  . LYS A 1 92  ? 161.277 175.881 172.505 1.00 88.32  ? 103 LYS A HZ2  1 
ATOM   1404 H  HZ3  . LYS A 1 92  ? 159.837 175.764 172.399 1.00 88.00  ? 103 LYS A HZ3  1 
ATOM   1405 N  N    . LEU A 1 93  ? 164.643 173.894 171.654 1.00 85.67  ? 104 LEU A N    1 
ATOM   1406 C  CA   . LEU A 1 93  ? 164.672 172.926 172.739 1.00 81.78  ? 104 LEU A CA   1 
ATOM   1407 C  C    . LEU A 1 93  ? 166.095 172.740 173.254 1.00 80.33  ? 104 LEU A C    1 
ATOM   1408 O  O    . LEU A 1 93  ? 167.068 172.817 172.499 1.00 87.02  ? 104 LEU A O    1 
ATOM   1409 C  CB   . LEU A 1 93  ? 164.106 171.590 172.262 1.00 83.27  ? 104 LEU A CB   1 
ATOM   1410 C  CG   . LEU A 1 93  ? 163.642 170.620 173.346 1.00 88.10  ? 104 LEU A CG   1 
ATOM   1411 C  CD1  . LEU A 1 93  ? 162.386 171.129 174.036 1.00 89.75  ? 104 LEU A CD1  1 
ATOM   1412 C  CD2  . LEU A 1 93  ? 163.399 169.255 172.739 1.00 87.83  ? 104 LEU A CD2  1 
ATOM   1413 H  H    . LEU A 1 93  ? 164.465 173.554 170.884 1.00 86.12  ? 104 LEU A H    1 
ATOM   1414 H  HA   . LEU A 1 93  ? 164.123 173.250 173.470 1.00 86.00  ? 104 LEU A HA   1 
ATOM   1415 H  HB2  . LEU A 1 93  ? 163.342 171.771 171.692 1.00 85.71  ? 104 LEU A HB2  1 
ATOM   1416 H  HB3  . LEU A 1 93  ? 164.791 171.140 171.745 1.00 85.23  ? 104 LEU A HB3  1 
ATOM   1417 H  HG   . LEU A 1 93  ? 164.341 170.534 174.012 1.00 85.83  ? 104 LEU A HG   1 
ATOM   1418 H  HD11 . LEU A 1 93  ? 162.120 170.491 174.717 1.00 86.21  ? 104 LEU A HD11 1 
ATOM   1419 H  HD12 . LEU A 1 93  ? 162.572 171.988 174.444 1.00 86.66  ? 104 LEU A HD12 1 
ATOM   1420 H  HD13 . LEU A 1 93  ? 161.680 171.221 173.377 1.00 86.16  ? 104 LEU A HD13 1 
ATOM   1421 H  HD21 . LEU A 1 93  ? 163.275 168.608 173.451 1.00 86.32  ? 104 LEU A HD21 1 
ATOM   1422 H  HD22 . LEU A 1 93  ? 162.604 169.298 172.186 1.00 85.52  ? 104 LEU A HD22 1 
ATOM   1423 H  HD23 . LEU A 1 93  ? 164.165 169.010 172.197 1.00 85.83  ? 104 LEU A HD23 1 
ATOM   1424 N  N    . SER A 1 94  ? 166.211 172.492 174.556 1.00 65.28  ? 105 SER A N    1 
ATOM   1425 C  CA   . SER A 1 94  ? 167.519 172.377 175.179 1.00 68.60  ? 105 SER A CA   1 
ATOM   1426 C  C    . SER A 1 94  ? 168.123 171.000 174.918 1.00 76.31  ? 105 SER A C    1 
ATOM   1427 O  O    . SER A 1 94  ? 167.463 170.078 174.433 1.00 82.71  ? 105 SER A O    1 
ATOM   1428 C  CB   . SER A 1 94  ? 167.429 172.632 176.680 1.00 68.64  ? 105 SER A CB   1 
ATOM   1429 O  OG   . SER A 1 94  ? 168.722 172.686 177.258 1.00 59.34  ? 105 SER A OG   1 
ATOM   1430 H  H    . SER A 1 94  ? 165.550 172.388 175.095 1.00 73.21  ? 105 SER A H    1 
ATOM   1431 H  HA   . SER A 1 94  ? 168.112 173.043 174.796 1.00 73.74  ? 105 SER A HA   1 
ATOM   1432 H  HB2  . SER A 1 94  ? 166.979 173.478 176.831 1.00 73.27  ? 105 SER A HB2  1 
ATOM   1433 H  HB3  . SER A 1 94  ? 166.927 171.912 177.094 1.00 72.79  ? 105 SER A HB3  1 
ATOM   1434 H  HG   . SER A 1 94  ? 168.662 172.820 178.085 1.00 72.17  ? 105 SER A HG   1 
ATOM   1435 N  N    . ALA A 1 95  ? 169.409 170.873 175.248 1.00 101.47 ? 106 ALA A N    1 
ATOM   1436 C  CA   . ALA A 1 95  ? 170.109 169.613 175.021 1.00 106.26 ? 106 ALA A CA   1 
ATOM   1437 C  C    . ALA A 1 95  ? 169.502 168.492 175.853 1.00 105.51 ? 106 ALA A C    1 
ATOM   1438 O  O    . ALA A 1 95  ? 169.260 167.390 175.348 1.00 107.07 ? 106 ALA A O    1 
ATOM   1439 C  CB   . ALA A 1 95  ? 171.595 169.778 175.340 1.00 103.42 ? 106 ALA A CB   1 
ATOM   1440 H  H    . ALA A 1 95  ? 169.891 171.492 175.600 1.00 101.57 ? 106 ALA A H    1 
ATOM   1441 H  HA   . ALA A 1 95  ? 170.028 169.371 174.085 1.00 103.45 ? 106 ALA A HA   1 
ATOM   1442 H  HB1  . ALA A 1 95  ? 171.692 170.036 176.270 1.00 102.78 ? 106 ALA A HB1  1 
ATOM   1443 H  HB2  . ALA A 1 95  ? 172.047 168.934 175.182 1.00 103.37 ? 106 ALA A HB2  1 
ATOM   1444 H  HB3  . ALA A 1 95  ? 171.966 170.465 174.765 1.00 103.27 ? 106 ALA A HB3  1 
ATOM   1445 N  N    . GLN A 1 96  ? 169.244 168.755 177.135 1.00 112.49 ? 107 GLN A N    1 
ATOM   1446 C  CA   . GLN A 1 96  ? 168.658 167.727 177.990 1.00 116.00 ? 107 GLN A CA   1 
ATOM   1447 C  C    . GLN A 1 96  ? 167.238 167.391 177.553 1.00 117.17 ? 107 GLN A C    1 
ATOM   1448 O  O    . GLN A 1 96  ? 166.867 166.213 177.476 1.00 117.88 ? 107 GLN A O    1 
ATOM   1449 C  CB   . GLN A 1 96  ? 168.679 168.185 179.448 1.00 116.10 ? 107 GLN A CB   1 
ATOM   1450 C  CG   . GLN A 1 96  ? 168.150 167.153 180.434 1.00 115.37 ? 107 GLN A CG   1 
ATOM   1451 C  CD   . GLN A 1 96  ? 168.937 165.857 180.402 1.00 113.86 ? 107 GLN A CD   1 
ATOM   1452 O  OE1  . GLN A 1 96  ? 168.496 164.864 179.824 1.00 113.85 ? 107 GLN A OE1  1 
ATOM   1453 N  NE2  . GLN A 1 96  ? 170.110 165.862 181.024 1.00 113.00 ? 107 GLN A NE2  1 
ATOM   1454 H  H    . GLN A 1 96  ? 169.395 169.505 177.526 1.00 112.95 ? 107 GLN A H    1 
ATOM   1455 H  HA   . GLN A 1 96  ? 169.192 166.920 177.919 1.00 114.52 ? 107 GLN A HA   1 
ATOM   1456 H  HB2  . GLN A 1 96  ? 169.594 168.389 179.697 1.00 114.53 ? 107 GLN A HB2  1 
ATOM   1457 H  HB3  . GLN A 1 96  ? 168.132 168.981 179.532 1.00 114.42 ? 107 GLN A HB3  1 
ATOM   1458 H  HG2  . GLN A 1 96  ? 168.209 167.516 181.332 1.00 114.55 ? 107 GLN A HG2  1 
ATOM   1459 H  HG3  . GLN A 1 96  ? 167.226 166.950 180.220 1.00 114.61 ? 107 GLN A HG3  1 
ATOM   1460 H  HE21 . GLN A 1 96  ? 170.386 166.575 181.417 1.00 114.39 ? 107 GLN A HE21 1 
ATOM   1461 H  HE22 . GLN A 1 96  ? 170.595 165.151 181.033 1.00 114.44 ? 107 GLN A HE22 1 
ATOM   1462 N  N    . GLU A 1 97  ? 166.428 168.411 177.261 1.00 112.41 ? 108 GLU A N    1 
ATOM   1463 C  CA   . GLU A 1 97  ? 165.070 168.162 176.791 1.00 111.83 ? 108 GLU A CA   1 
ATOM   1464 C  C    . GLU A 1 97  ? 165.078 167.452 175.443 1.00 109.99 ? 108 GLU A C    1 
ATOM   1465 O  O    . GLU A 1 97  ? 164.258 166.559 175.196 1.00 107.99 ? 108 GLU A O    1 
ATOM   1466 C  CB   . GLU A 1 97  ? 164.300 169.479 176.705 1.00 110.22 ? 108 GLU A CB   1 
ATOM   1467 C  CG   . GLU A 1 97  ? 164.122 170.177 178.045 1.00 110.71 ? 108 GLU A CG   1 
ATOM   1468 C  CD   . GLU A 1 97  ? 163.582 171.587 177.903 1.00 110.15 ? 108 GLU A CD   1 
ATOM   1469 O  OE1  . GLU A 1 97  ? 163.356 172.027 176.757 1.00 111.72 ? 108 GLU A OE1  1 
ATOM   1470 O  OE2  . GLU A 1 97  ? 163.384 172.256 178.939 1.00 106.87 ? 108 GLU A OE2  1 
ATOM   1471 H  H    . GLU A 1 97  ? 166.640 169.242 177.325 1.00 108.09 ? 108 GLU A H    1 
ATOM   1472 H  HA   . GLU A 1 97  ? 164.615 167.589 177.429 1.00 109.05 ? 108 GLU A HA   1 
ATOM   1473 H  HB2  . GLU A 1 97  ? 164.785 170.083 176.123 1.00 107.48 ? 108 GLU A HB2  1 
ATOM   1474 H  HB3  . GLU A 1 97  ? 163.418 169.305 176.340 1.00 108.32 ? 108 GLU A HB3  1 
ATOM   1475 H  HG2  . GLU A 1 97  ? 163.496 169.670 178.585 1.00 109.03 ? 108 GLU A HG2  1 
ATOM   1476 H  HG3  . GLU A 1 97  ? 164.981 170.229 178.492 1.00 108.26 ? 108 GLU A HG3  1 
ATOM   1477 N  N    . ARG A 1 98  ? 165.996 167.839 174.555 1.00 105.99 ? 109 ARG A N    1 
ATOM   1478 C  CA   . ARG A 1 98  ? 166.101 167.164 173.266 1.00 105.75 ? 109 ARG A CA   1 
ATOM   1479 C  C    . ARG A 1 98  ? 166.465 165.696 173.449 1.00 105.93 ? 109 ARG A C    1 
ATOM   1480 O  O    . ARG A 1 98  ? 165.894 164.819 172.790 1.00 105.34 ? 109 ARG A O    1 
ATOM   1481 C  CB   . ARG A 1 98  ? 167.133 167.876 172.389 1.00 103.84 ? 109 ARG A CB   1 
ATOM   1482 C  CG   . ARG A 1 98  ? 167.243 167.329 170.974 1.00 103.83 ? 109 ARG A CG   1 
ATOM   1483 C  CD   . ARG A 1 98  ? 168.467 167.876 170.255 1.00 103.58 ? 109 ARG A CD   1 
ATOM   1484 N  NE   . ARG A 1 98  ? 168.694 167.217 168.974 1.00 105.28 ? 109 ARG A NE   1 
ATOM   1485 C  CZ   . ARG A 1 98  ? 169.097 165.961 168.834 1.00 103.49 ? 109 ARG A CZ   1 
ATOM   1486 N  NH1  . ARG A 1 98  ? 169.343 165.192 169.882 1.00 104.25 ? 109 ARG A NH1  1 
ATOM   1487 N  NH2  . ARG A 1 98  ? 169.260 165.465 167.610 1.00 100.13 ? 109 ARG A NH2  1 
ATOM   1488 H  H    . ARG A 1 98  ? 166.559 168.478 174.673 1.00 102.86 ? 109 ARG A H    1 
ATOM   1489 H  HA   . ARG A 1 98  ? 165.244 167.202 172.815 1.00 103.37 ? 109 ARG A HA   1 
ATOM   1490 H  HB2  . ARG A 1 98  ? 166.892 168.813 172.324 1.00 102.40 ? 109 ARG A HB2  1 
ATOM   1491 H  HB3  . ARG A 1 98  ? 168.005 167.792 172.806 1.00 102.83 ? 109 ARG A HB3  1 
ATOM   1492 H  HG2  . ARG A 1 98  ? 167.320 166.364 171.007 1.00 103.35 ? 109 ARG A HG2  1 
ATOM   1493 H  HG3  . ARG A 1 98  ? 166.455 167.585 170.470 1.00 102.65 ? 109 ARG A HG3  1 
ATOM   1494 H  HD2  . ARG A 1 98  ? 168.342 168.823 170.090 1.00 102.90 ? 109 ARG A HD2  1 
ATOM   1495 H  HD3  . ARG A 1 98  ? 169.251 167.735 170.810 1.00 103.12 ? 109 ARG A HD3  1 
ATOM   1496 H  HE   . ARG A 1 98  ? 168.568 167.679 168.259 1.00 103.40 ? 109 ARG A HE   1 
ATOM   1497 H  HH11 . ARG A 1 98  ? 169.242 165.500 170.678 1.00 103.51 ? 109 ARG A HH11 1 
ATOM   1498 H  HH12 . ARG A 1 98  ? 169.604 164.381 169.766 1.00 103.21 ? 109 ARG A HH12 1 
ATOM   1499 H  HH21 . ARG A 1 98  ? 169.103 165.957 166.923 1.00 102.80 ? 109 ARG A HH21 1 
ATOM   1500 H  HH22 . ARG A 1 98  ? 169.522 164.653 167.507 1.00 102.73 ? 109 ARG A HH22 1 
ATOM   1501 N  N    . LYS A 1 99  ? 167.409 165.408 174.346 1.00 111.47 ? 110 LYS A N    1 
ATOM   1502 C  CA   . LYS A 1 99  ? 167.776 164.020 174.605 1.00 110.80 ? 110 LYS A CA   1 
ATOM   1503 C  C    . LYS A 1 99  ? 166.608 163.249 175.203 1.00 109.35 ? 110 LYS A C    1 
ATOM   1504 O  O    . LYS A 1 99  ? 166.406 162.072 174.888 1.00 107.79 ? 110 LYS A O    1 
ATOM   1505 C  CB   . LYS A 1 99  ? 168.990 163.962 175.533 1.00 110.95 ? 110 LYS A CB   1 
ATOM   1506 C  CG   . LYS A 1 99  ? 169.502 162.553 175.789 1.00 111.35 ? 110 LYS A CG   1 
ATOM   1507 C  CD   . LYS A 1 99  ? 170.808 162.560 176.569 1.00 111.10 ? 110 LYS A CD   1 
ATOM   1508 C  CE   . LYS A 1 99  ? 170.597 162.957 178.023 1.00 112.18 ? 110 LYS A CE   1 
ATOM   1509 N  NZ   . LYS A 1 99  ? 169.779 161.958 178.765 1.00 112.09 ? 110 LYS A NZ   1 
ATOM   1510 H  H    . LYS A 1 99  ? 167.844 165.987 174.809 1.00 110.31 ? 110 LYS A H    1 
ATOM   1511 H  HA   . LYS A 1 99  ? 168.019 163.596 173.767 1.00 110.11 ? 110 LYS A HA   1 
ATOM   1512 H  HB2  . LYS A 1 99  ? 169.712 164.473 175.135 1.00 110.63 ? 110 LYS A HB2  1 
ATOM   1513 H  HB3  . LYS A 1 99  ? 168.745 164.350 176.388 1.00 110.57 ? 110 LYS A HB3  1 
ATOM   1514 H  HG2  . LYS A 1 99  ? 168.844 162.061 176.303 1.00 110.87 ? 110 LYS A HG2  1 
ATOM   1515 H  HG3  . LYS A 1 99  ? 169.660 162.112 174.939 1.00 110.85 ? 110 LYS A HG3  1 
ATOM   1516 H  HD2  . LYS A 1 99  ? 171.196 161.671 176.551 1.00 110.78 ? 110 LYS A HD2  1 
ATOM   1517 H  HD3  . LYS A 1 99  ? 171.417 163.199 176.166 1.00 110.28 ? 110 LYS A HD3  1 
ATOM   1518 H  HE2  . LYS A 1 99  ? 171.460 163.024 178.461 1.00 110.91 ? 110 LYS A HE2  1 
ATOM   1519 H  HE3  . LYS A 1 99  ? 170.139 163.811 178.060 1.00 110.66 ? 110 LYS A HE3  1 
ATOM   1520 H  HZ1  . LYS A 1 99  ? 169.716 162.193 179.621 1.00 110.75 ? 110 LYS A HZ1  1 
ATOM   1521 H  HZ2  . LYS A 1 99  ? 168.962 161.913 178.416 1.00 110.79 ? 110 LYS A HZ2  1 
ATOM   1522 H  HZ3  . LYS A 1 99  ? 170.160 161.155 178.713 1.00 110.71 ? 110 LYS A HZ3  1 
ATOM   1523 N  N    . GLU A 1 100 ? 165.831 163.892 176.077 1.00 98.51  ? 111 GLU A N    1 
ATOM   1524 C  CA   . GLU A 1 100 ? 164.657 163.234 176.641 1.00 94.79  ? 111 GLU A CA   1 
ATOM   1525 C  C    . GLU A 1 100 ? 163.642 162.902 175.552 1.00 99.44  ? 111 GLU A C    1 
ATOM   1526 O  O    . GLU A 1 100 ? 163.060 161.810 175.543 1.00 103.28 ? 111 GLU A O    1 
ATOM   1527 C  CB   . GLU A 1 100 ? 164.027 164.125 177.712 1.00 94.80  ? 111 GLU A CB   1 
ATOM   1528 C  CG   . GLU A 1 100 ? 162.690 163.627 178.240 1.00 99.00  ? 111 GLU A CG   1 
ATOM   1529 C  CD   . GLU A 1 100 ? 162.739 162.173 178.669 1.00 100.71 ? 111 GLU A CD   1 
ATOM   1530 O  OE1  . GLU A 1 100 ? 163.581 161.834 179.527 1.00 101.29 ? 111 GLU A OE1  1 
ATOM   1531 O  OE2  . GLU A 1 100 ? 161.936 161.369 178.152 1.00 98.78  ? 111 GLU A OE2  1 
ATOM   1532 H  H    . GLU A 1 100 ? 165.961 164.696 176.354 1.00 100.19 ? 111 GLU A H    1 
ATOM   1533 H  HA   . GLU A 1 100 ? 164.931 162.404 177.061 1.00 98.60  ? 111 GLU A HA   1 
ATOM   1534 H  HB2  . GLU A 1 100 ? 164.636 164.185 178.465 1.00 98.61  ? 111 GLU A HB2  1 
ATOM   1535 H  HB3  . GLU A 1 100 ? 163.884 165.008 177.337 1.00 98.74  ? 111 GLU A HB3  1 
ATOM   1536 H  HG2  . GLU A 1 100 ? 162.438 164.158 179.011 1.00 99.16  ? 111 GLU A HG2  1 
ATOM   1537 H  HG3  . GLU A 1 100 ? 162.019 163.715 177.545 1.00 98.99  ? 111 GLU A HG3  1 
ATOM   1538 N  N    . LEU A 1 101 ? 163.418 163.835 174.623 1.00 99.08  ? 112 LEU A N    1 
ATOM   1539 C  CA   . LEU A 1 101 ? 162.504 163.570 173.515 1.00 98.48  ? 112 LEU A CA   1 
ATOM   1540 C  C    . LEU A 1 101 ? 163.014 162.432 172.637 1.00 100.14 ? 112 LEU A C    1 
ATOM   1541 O  O    . LEU A 1 101 ? 162.235 161.575 172.202 1.00 95.01  ? 112 LEU A O    1 
ATOM   1542 C  CB   . LEU A 1 101 ? 162.302 164.837 172.684 1.00 96.01  ? 112 LEU A CB   1 
ATOM   1543 C  CG   . LEU A 1 101 ? 161.112 165.713 173.080 1.00 94.91  ? 112 LEU A CG   1 
ATOM   1544 C  CD1  . LEU A 1 101 ? 161.300 166.317 174.463 1.00 95.75  ? 112 LEU A CD1  1 
ATOM   1545 C  CD2  . LEU A 1 101 ? 160.898 166.801 172.042 1.00 93.83  ? 112 LEU A CD2  1 
ATOM   1546 H  H    . LEU A 1 101 ? 163.777 164.616 174.613 1.00 96.32  ? 112 LEU A H    1 
ATOM   1547 H  HA   . LEU A 1 101 ? 161.641 163.307 173.874 1.00 95.28  ? 112 LEU A HA   1 
ATOM   1548 H  HB2  . LEU A 1 101 ? 163.101 165.382 172.757 1.00 95.42  ? 112 LEU A HB2  1 
ATOM   1549 H  HB3  . LEU A 1 101 ? 162.173 164.576 171.759 1.00 94.90  ? 112 LEU A HB3  1 
ATOM   1550 H  HG   . LEU A 1 101 ? 160.312 165.163 173.103 1.00 94.76  ? 112 LEU A HG   1 
ATOM   1551 H  HD11 . LEU A 1 101 ? 160.475 166.751 174.732 1.00 94.89  ? 112 LEU A HD11 1 
ATOM   1552 H  HD12 . LEU A 1 101 ? 161.522 165.612 175.090 1.00 95.44  ? 112 LEU A HD12 1 
ATOM   1553 H  HD13 . LEU A 1 101 ? 162.018 166.968 174.427 1.00 95.58  ? 112 LEU A HD13 1 
ATOM   1554 H  HD21 . LEU A 1 101 ? 160.185 167.388 172.340 1.00 93.83  ? 112 LEU A HD21 1 
ATOM   1555 H  HD22 . LEU A 1 101 ? 161.720 167.303 171.941 1.00 93.92  ? 112 LEU A HD22 1 
ATOM   1556 H  HD23 . LEU A 1 101 ? 160.659 166.389 171.197 1.00 94.15  ? 112 LEU A HD23 1 
ATOM   1557 N  N    . LEU A 1 102 ? 164.319 162.411 172.358 1.00 99.80  ? 113 LEU A N    1 
ATOM   1558 C  CA   . LEU A 1 102 ? 164.880 161.313 171.575 1.00 94.55  ? 113 LEU A CA   1 
ATOM   1559 C  C    . LEU A 1 102 ? 164.720 159.982 172.299 1.00 95.72  ? 113 LEU A C    1 
ATOM   1560 O  O    . LEU A 1 102 ? 164.410 158.962 171.674 1.00 93.80  ? 113 LEU A O    1 
ATOM   1561 C  CB   . LEU A 1 102 ? 166.351 161.580 171.257 1.00 93.42  ? 113 LEU A CB   1 
ATOM   1562 C  CG   . LEU A 1 102 ? 166.617 162.388 169.984 1.00 95.08  ? 113 LEU A CG   1 
ATOM   1563 C  CD1  . LEU A 1 102 ? 166.273 163.851 170.164 1.00 93.60  ? 113 LEU A CD1  1 
ATOM   1564 C  CD2  . LEU A 1 102 ? 168.068 162.229 169.556 1.00 96.28  ? 113 LEU A CD2  1 
ATOM   1565 H  H    . LEU A 1 102 ? 164.888 163.006 172.606 1.00 96.29  ? 113 LEU A H    1 
ATOM   1566 H  HA   . LEU A 1 102 ? 164.400 161.253 170.734 1.00 95.39  ? 113 LEU A HA   1 
ATOM   1567 H  HB2  . LEU A 1 102 ? 166.741 162.070 171.998 1.00 95.18  ? 113 LEU A HB2  1 
ATOM   1568 H  HB3  . LEU A 1 102 ? 166.803 160.728 171.160 1.00 95.76  ? 113 LEU A HB3  1 
ATOM   1569 H  HG   . LEU A 1 102 ? 166.059 162.039 169.271 1.00 95.92  ? 113 LEU A HG   1 
ATOM   1570 H  HD11 . LEU A 1 102 ? 166.294 164.289 169.299 1.00 95.49  ? 113 LEU A HD11 1 
ATOM   1571 H  HD12 . LEU A 1 102 ? 165.387 163.924 170.552 1.00 95.11  ? 113 LEU A HD12 1 
ATOM   1572 H  HD13 . LEU A 1 102 ? 166.930 164.249 170.753 1.00 95.73  ? 113 LEU A HD13 1 
ATOM   1573 H  HD21 . LEU A 1 102 ? 168.236 162.803 168.792 1.00 95.60  ? 113 LEU A HD21 1 
ATOM   1574 H  HD22 . LEU A 1 102 ? 168.644 162.483 170.294 1.00 95.68  ? 113 LEU A HD22 1 
ATOM   1575 H  HD23 . LEU A 1 102 ? 168.227 161.303 169.316 1.00 95.88  ? 113 LEU A HD23 1 
ATOM   1576 N  N    . ALA A 1 103 ? 164.930 159.969 173.616 1.00 104.99 ? 114 ALA A N    1 
ATOM   1577 C  CA   . ALA A 1 103 ? 164.731 158.744 174.382 1.00 106.70 ? 114 ALA A CA   1 
ATOM   1578 C  C    . ALA A 1 103 ? 163.281 158.287 174.310 1.00 105.19 ? 114 ALA A C    1 
ATOM   1579 O  O    . ALA A 1 103 ? 163.004 157.089 174.179 1.00 105.24 ? 114 ALA A O    1 
ATOM   1580 C  CB   . ALA A 1 103 ? 165.156 158.959 175.835 1.00 104.00 ? 114 ALA A CB   1 
ATOM   1581 H  H    . ALA A 1 103 ? 165.183 160.647 174.081 1.00 104.00 ? 114 ALA A H    1 
ATOM   1582 H  HA   . ALA A 1 103 ? 165.287 158.043 174.007 1.00 104.47 ? 114 ALA A HA   1 
ATOM   1583 H  HB1  . ALA A 1 103 ? 166.094 159.204 175.856 1.00 104.09 ? 114 ALA A HB1  1 
ATOM   1584 H  HB2  . ALA A 1 103 ? 164.619 159.670 176.218 1.00 103.79 ? 114 ALA A HB2  1 
ATOM   1585 H  HB3  . ALA A 1 103 ? 165.017 158.136 176.329 1.00 104.44 ? 114 ALA A HB3  1 
ATOM   1586 N  N    . ASP A 1 104 ? 162.340 159.230 174.394 1.00 100.99 ? 115 ASP A N    1 
ATOM   1587 C  CA   . ASP A 1 104 ? 160.933 158.878 174.229 1.00 100.08 ? 115 ASP A CA   1 
ATOM   1588 C  C    . ASP A 1 104 ? 160.684 158.266 172.857 1.00 96.89  ? 115 ASP A C    1 
ATOM   1589 O  O    . ASP A 1 104 ? 159.963 157.269 172.733 1.00 98.76  ? 115 ASP A O    1 
ATOM   1590 C  CB   . ASP A 1 104 ? 160.055 160.115 174.424 1.00 103.68 ? 115 ASP A CB   1 
ATOM   1591 C  CG   . ASP A 1 104 ? 159.901 160.501 175.881 1.00 107.23 ? 115 ASP A CG   1 
ATOM   1592 O  OD1  . ASP A 1 104 ? 159.431 159.660 176.677 1.00 105.86 ? 115 ASP A OD1  1 
ATOM   1593 O  OD2  . ASP A 1 104 ? 160.245 161.649 176.230 1.00 105.67 ? 115 ASP A OD2  1 
ATOM   1594 H  H    . ASP A 1 104 ? 162.488 160.064 174.542 1.00 101.87 ? 115 ASP A H    1 
ATOM   1595 H  HA   . ASP A 1 104 ? 160.687 158.224 174.901 1.00 101.87 ? 115 ASP A HA   1 
ATOM   1596 H  HB2  . ASP A 1 104 ? 160.454 160.864 173.955 1.00 101.56 ? 115 ASP A HB2  1 
ATOM   1597 H  HB3  . ASP A 1 104 ? 159.171 159.933 174.067 1.00 101.85 ? 115 ASP A HB3  1 
ATOM   1598 N  N    . LEU A 1 105 ? 161.275 158.852 171.814 1.00 84.78  ? 116 LEU A N    1 
ATOM   1599 C  CA   . LEU A 1 105 ? 161.089 158.326 170.466 1.00 87.25  ? 116 LEU A CA   1 
ATOM   1600 C  C    . LEU A 1 105 ? 161.649 156.914 170.337 1.00 88.56  ? 116 LEU A C    1 
ATOM   1601 O  O    . LEU A 1 105 ? 161.026 156.044 169.718 1.00 84.02  ? 116 LEU A O    1 
ATOM   1602 C  CB   . LEU A 1 105 ? 161.749 159.252 169.445 1.00 86.50  ? 116 LEU A CB   1 
ATOM   1603 C  CG   . LEU A 1 105 ? 161.000 160.540 169.103 1.00 85.06  ? 116 LEU A CG   1 
ATOM   1604 C  CD1  . LEU A 1 105 ? 161.884 161.454 168.272 1.00 83.28  ? 116 LEU A CD1  1 
ATOM   1605 C  CD2  . LEU A 1 105 ? 159.705 160.239 168.364 1.00 82.43  ? 116 LEU A CD2  1 
ATOM   1606 H  H    . LEU A 1 105 ? 161.780 159.546 171.861 1.00 86.22  ? 116 LEU A H    1 
ATOM   1607 H  HA   . LEU A 1 105 ? 160.141 158.288 170.272 1.00 85.36  ? 116 LEU A HA   1 
ATOM   1608 H  HB2  . LEU A 1 105 ? 162.619 159.509 169.788 1.00 86.21  ? 116 LEU A HB2  1 
ATOM   1609 H  HB3  . LEU A 1 105 ? 161.863 158.759 168.618 1.00 85.18  ? 116 LEU A HB3  1 
ATOM   1610 H  HG   . LEU A 1 105 ? 160.776 161.005 169.924 1.00 85.87  ? 116 LEU A HG   1 
ATOM   1611 H  HD11 . LEU A 1 105 ? 161.429 162.299 168.143 1.00 84.98  ? 116 LEU A HD11 1 
ATOM   1612 H  HD12 . LEU A 1 105 ? 162.720 161.596 168.743 1.00 85.30  ? 116 LEU A HD12 1 
ATOM   1613 H  HD13 . LEU A 1 105 ? 162.055 161.033 167.415 1.00 84.39  ? 116 LEU A HD13 1 
ATOM   1614 H  HD21 . LEU A 1 105 ? 159.275 161.075 168.128 1.00 84.99  ? 116 LEU A HD21 1 
ATOM   1615 H  HD22 . LEU A 1 105 ? 159.910 159.734 167.561 1.00 84.51  ? 116 LEU A HD22 1 
ATOM   1616 H  HD23 . LEU A 1 105 ? 159.122 159.721 168.941 1.00 84.64  ? 116 LEU A HD23 1 
ATOM   1617 N  N    . GLU A 1 106 ? 162.827 156.667 170.915 1.00 87.62  ? 117 GLU A N    1 
ATOM   1618 C  CA   . GLU A 1 106 ? 163.499 155.382 170.759 1.00 80.43  ? 117 GLU A CA   1 
ATOM   1619 C  C    . GLU A 1 106 ? 162.744 154.226 171.402 1.00 84.20  ? 117 GLU A C    1 
ATOM   1620 O  O    . GLU A 1 106 ? 163.067 153.069 171.113 1.00 86.44  ? 117 GLU A O    1 
ATOM   1621 C  CB   . GLU A 1 106 ? 164.910 155.458 171.343 1.00 78.00  ? 117 GLU A CB   1 
ATOM   1622 C  CG   . GLU A 1 106 ? 165.841 156.393 170.592 1.00 81.85  ? 117 GLU A CG   1 
ATOM   1623 C  CD   . GLU A 1 106 ? 166.152 155.903 169.190 1.00 88.76  ? 117 GLU A CD   1 
ATOM   1624 O  OE1  . GLU A 1 106 ? 166.190 154.672 168.985 1.00 89.85  ? 117 GLU A OE1  1 
ATOM   1625 O  OE2  . GLU A 1 106 ? 166.358 156.749 168.294 1.00 87.85  ? 117 GLU A OE2  1 
ATOM   1626 H  H    . GLU A 1 106 ? 163.255 157.231 171.403 1.00 86.30  ? 117 GLU A H    1 
ATOM   1627 H  HA   . GLU A 1 106 ? 163.580 155.189 169.813 1.00 84.93  ? 117 GLU A HA   1 
ATOM   1628 H  HB2  . GLU A 1 106 ? 164.852 155.772 172.259 1.00 84.47  ? 117 GLU A HB2  1 
ATOM   1629 H  HB3  . GLU A 1 106 ? 165.303 154.571 171.326 1.00 84.95  ? 117 GLU A HB3  1 
ATOM   1630 H  HG2  . GLU A 1 106 ? 165.422 157.262 170.511 1.00 85.03  ? 117 GLU A HG2  1 
ATOM   1631 H  HG3  . GLU A 1 106 ? 166.676 156.469 171.078 1.00 85.18  ? 117 GLU A HG3  1 
ATOM   1632 N  N    . ARG A 1 107 ? 161.761 154.498 172.256 1.00 95.41  ? 118 ARG A N    1 
ATOM   1633 C  CA   . ARG A 1 107 ? 160.995 153.421 172.863 1.00 95.51  ? 118 ARG A CA   1 
ATOM   1634 C  C    . ARG A 1 107 ? 160.321 152.577 171.785 1.00 94.47  ? 118 ARG A C    1 
ATOM   1635 O  O    . ARG A 1 107 ? 160.140 153.007 170.642 1.00 93.51  ? 118 ARG A O    1 
ATOM   1636 C  CB   . ARG A 1 107 ? 159.946 153.986 173.821 1.00 95.19  ? 118 ARG A CB   1 
ATOM   1637 H  H    . ARG A 1 107 ? 161.522 155.288 172.497 1.00 94.41  ? 118 ARG A H    1 
ATOM   1638 H  HA   . ARG A 1 107 ? 161.592 152.849 173.370 1.00 93.91  ? 118 ARG A HA   1 
ATOM   1639 N  N    . GLU A 1 108 ? 159.956 151.349 172.160 1.00 94.35  ? 119 GLU A N    1 
ATOM   1640 C  CA   . GLU A 1 108 ? 159.284 150.458 171.219 1.00 93.21  ? 119 GLU A CA   1 
ATOM   1641 C  C    . GLU A 1 108 ? 158.061 151.136 170.614 1.00 93.24  ? 119 GLU A C    1 
ATOM   1642 O  O    . GLU A 1 108 ? 157.882 151.151 169.391 1.00 91.59  ? 119 GLU A O    1 
ATOM   1643 C  CB   . GLU A 1 108 ? 158.891 149.157 171.920 1.00 94.63  ? 119 GLU A CB   1 
ATOM   1644 C  CG   . GLU A 1 108 ? 158.317 148.102 170.987 1.00 95.73  ? 119 GLU A CG   1 
ATOM   1645 C  CD   . GLU A 1 108 ? 158.072 146.779 171.685 1.00 96.49  ? 119 GLU A CD   1 
ATOM   1646 O  OE1  . GLU A 1 108 ? 158.329 146.691 172.904 1.00 94.25  ? 119 GLU A OE1  1 
ATOM   1647 O  OE2  . GLU A 1 108 ? 157.623 145.826 171.014 1.00 97.42  ? 119 GLU A OE2  1 
ATOM   1648 H  H    . GLU A 1 108 ? 160.084 151.013 172.942 1.00 94.25  ? 119 GLU A H    1 
ATOM   1649 H  HA   . GLU A 1 108 ? 159.895 150.240 170.497 1.00 94.03  ? 119 GLU A HA   1 
ATOM   1650 H  HB2  . GLU A 1 108 ? 159.678 148.782 172.344 1.00 94.23  ? 119 GLU A HB2  1 
ATOM   1651 H  HB3  . GLU A 1 108 ? 158.219 149.356 172.590 1.00 94.10  ? 119 GLU A HB3  1 
ATOM   1652 H  HG2  . GLU A 1 108 ? 157.470 148.417 170.635 1.00 94.15  ? 119 GLU A HG2  1 
ATOM   1653 H  HG3  . GLU A 1 108 ? 158.942 147.948 170.262 1.00 94.78  ? 119 GLU A HG3  1 
ATOM   1654 N  N    . LYS A 1 109 ? 157.207 151.702 171.462 1.00 93.38  ? 120 LYS A N    1 
ATOM   1655 C  CA   . LYS A 1 109 ? 156.112 152.556 171.016 1.00 93.48  ? 120 LYS A CA   1 
ATOM   1656 C  C    . LYS A 1 109 ? 156.415 153.983 171.448 1.00 89.54  ? 120 LYS A C    1 
ATOM   1657 O  O    . LYS A 1 109 ? 156.358 154.279 172.652 1.00 87.41  ? 120 LYS A O    1 
ATOM   1658 C  CB   . LYS A 1 109 ? 154.778 152.089 171.601 1.00 92.78  ? 120 LYS A CB   1 
ATOM   1659 C  CG   . LYS A 1 109 ? 153.597 153.010 171.302 1.00 92.86  ? 120 LYS A CG   1 
ATOM   1660 C  CD   . LYS A 1 109 ? 153.312 153.109 169.808 1.00 94.33  ? 120 LYS A CD   1 
ATOM   1661 C  CE   . LYS A 1 109 ? 152.355 154.250 169.498 1.00 91.77  ? 120 LYS A CE   1 
ATOM   1662 N  NZ   . LYS A 1 109 ? 153.041 155.382 168.814 1.00 92.61  ? 120 LYS A NZ   1 
ATOM   1663 H  H    . LYS A 1 109 ? 157.242 151.606 172.316 1.00 90.96  ? 120 LYS A H    1 
ATOM   1664 H  HA   . LYS A 1 109 ? 156.047 152.513 170.052 1.00 91.08  ? 120 LYS A HA   1 
ATOM   1665 H  HB2  . LYS A 1 109 ? 154.569 151.214 171.237 1.00 91.26  ? 120 LYS A HB2  1 
ATOM   1666 H  HB3  . LYS A 1 109 ? 154.867 152.028 172.565 1.00 90.79  ? 120 LYS A HB3  1 
ATOM   1667 H  HG2  . LYS A 1 109 ? 152.804 152.656 171.734 1.00 90.80  ? 120 LYS A HG2  1 
ATOM   1668 H  HG3  . LYS A 1 109 ? 153.785 153.900 171.636 1.00 91.15  ? 120 LYS A HG3  1 
ATOM   1669 H  HD2  . LYS A 1 109 ? 154.137 153.275 169.327 1.00 91.35  ? 120 LYS A HD2  1 
ATOM   1670 H  HD3  . LYS A 1 109 ? 152.906 152.282 169.504 1.00 91.03  ? 120 LYS A HD3  1 
ATOM   1671 H  HE2  . LYS A 1 109 ? 151.652 153.926 168.915 1.00 90.11  ? 120 LYS A HE2  1 
ATOM   1672 H  HE3  . LYS A 1 109 ? 151.976 154.583 170.327 1.00 90.58  ? 120 LYS A HE3  1 
ATOM   1673 H  HZ1  . LYS A 1 109 ? 152.458 156.031 168.642 1.00 90.05  ? 120 LYS A HZ1  1 
ATOM   1674 H  HZ2  . LYS A 1 109 ? 153.688 155.705 169.334 1.00 90.70  ? 120 LYS A HZ2  1 
ATOM   1675 H  HZ3  . LYS A 1 109 ? 153.398 155.103 168.048 1.00 90.24  ? 120 LYS A HZ3  1 
ATOM   1676 N  N    . PRO A 1 110 ? 156.747 154.896 170.534 1.00 79.66  ? 121 PRO A N    1 
ATOM   1677 C  CA   . PRO A 1 110 ? 157.151 156.241 170.962 1.00 80.21  ? 121 PRO A CA   1 
ATOM   1678 C  C    . PRO A 1 110 ? 156.076 156.907 171.807 1.00 80.14  ? 121 PRO A C    1 
ATOM   1679 O  O    . PRO A 1 110 ? 154.885 156.848 171.497 1.00 77.44  ? 121 PRO A O    1 
ATOM   1680 C  CB   . PRO A 1 110 ? 157.369 156.986 169.641 1.00 82.40  ? 121 PRO A CB   1 
ATOM   1681 C  CG   . PRO A 1 110 ? 157.611 155.923 168.630 1.00 87.46  ? 121 PRO A CG   1 
ATOM   1682 C  CD   . PRO A 1 110 ? 156.804 154.742 169.070 1.00 81.14  ? 121 PRO A CD   1 
ATOM   1683 H  HA   . PRO A 1 110 ? 157.983 156.206 171.458 1.00 82.25  ? 121 PRO A HA   1 
ATOM   1684 H  HB2  . PRO A 1 110 ? 156.573 157.494 169.425 1.00 81.41  ? 121 PRO A HB2  1 
ATOM   1685 H  HB3  . PRO A 1 110 ? 158.138 157.570 169.716 1.00 81.79  ? 121 PRO A HB3  1 
ATOM   1686 H  HG2  . PRO A 1 110 ? 157.316 156.231 167.759 1.00 82.62  ? 121 PRO A HG2  1 
ATOM   1687 H  HG3  . PRO A 1 110 ? 158.555 155.703 168.612 1.00 82.67  ? 121 PRO A HG3  1 
ATOM   1688 H  HD2  . PRO A 1 110 ? 155.912 154.780 168.689 1.00 81.91  ? 121 PRO A HD2  1 
ATOM   1689 H  HD3  . PRO A 1 110 ? 157.260 153.920 168.832 1.00 82.09  ? 121 PRO A HD3  1 
ATOM   1690 N  N    . GLN A 1 111 ? 156.517 157.555 172.887 1.00 90.69  ? 122 GLN A N    1 
ATOM   1691 C  CA   . GLN A 1 111 ? 155.578 158.229 173.778 1.00 91.51  ? 122 GLN A CA   1 
ATOM   1692 C  C    . GLN A 1 111 ? 154.887 159.391 173.075 1.00 89.67  ? 122 GLN A C    1 
ATOM   1693 O  O    . GLN A 1 111 ? 153.686 159.615 173.269 1.00 90.45  ? 122 GLN A O    1 
ATOM   1694 C  CB   . GLN A 1 111 ? 156.305 158.714 175.033 1.00 90.02  ? 122 GLN A CB   1 
ATOM   1695 C  CG   . GLN A 1 111 ? 157.142 157.645 175.731 1.00 91.63  ? 122 GLN A CG   1 
ATOM   1696 C  CD   . GLN A 1 111 ? 156.428 156.307 175.838 1.00 87.62  ? 122 GLN A CD   1 
ATOM   1697 O  OE1  . GLN A 1 111 ? 156.887 155.299 175.300 1.00 84.47  ? 122 GLN A OE1  1 
ATOM   1698 N  NE2  . GLN A 1 111 ? 155.303 156.291 176.545 1.00 84.06  ? 122 GLN A NE2  1 
ATOM   1699 H  H    . GLN A 1 111 ? 157.342 157.618 173.121 1.00 89.16  ? 122 GLN A H    1 
ATOM   1700 H  HA   . GLN A 1 111 ? 154.893 157.599 174.050 1.00 89.08  ? 122 GLN A HA   1 
ATOM   1701 H  HB2  . GLN A 1 111 ? 156.900 159.439 174.785 1.00 88.79  ? 122 GLN A HB2  1 
ATOM   1702 H  HB3  . GLN A 1 111 ? 155.647 159.035 175.669 1.00 88.29  ? 122 GLN A HB3  1 
ATOM   1703 H  HG2  . GLN A 1 111 ? 157.960 157.508 175.228 1.00 89.53  ? 122 GLN A HG2  1 
ATOM   1704 H  HG3  . GLN A 1 111 ? 157.352 157.946 176.629 1.00 88.75  ? 122 GLN A HG3  1 
ATOM   1705 H  HE21 . GLN A 1 111 ? 155.014 157.015 176.908 1.00 87.87  ? 122 GLN A HE21 1 
ATOM   1706 H  HE22 . GLN A 1 111 ? 154.863 155.558 176.636 1.00 87.51  ? 122 GLN A HE22 1 
ATOM   1707 N  N    . THR A 1 112 ? 155.623 160.139 172.256 1.00 80.03  ? 123 THR A N    1 
ATOM   1708 C  CA   . THR A 1 112 ? 155.065 161.293 171.557 1.00 76.03  ? 123 THR A CA   1 
ATOM   1709 C  C    . THR A 1 112 ? 154.303 160.811 170.328 1.00 74.73  ? 123 THR A C    1 
ATOM   1710 O  O    . THR A 1 112 ? 154.902 160.340 169.356 1.00 74.34  ? 123 THR A O    1 
ATOM   1711 C  CB   . THR A 1 112 ? 156.167 162.279 171.176 1.00 76.03  ? 123 THR A CB   1 
ATOM   1712 O  OG1  . THR A 1 112 ? 155.582 163.439 170.571 1.00 81.89  ? 123 THR A OG1  1 
ATOM   1713 C  CG2  . THR A 1 112 ? 157.166 161.655 170.205 1.00 79.63  ? 123 THR A CG2  1 
ATOM   1714 H  H    . THR A 1 112 ? 156.455 159.997 172.092 1.00 79.32  ? 123 THR A H    1 
ATOM   1715 H  HA   . THR A 1 112 ? 154.440 161.749 172.142 1.00 78.07  ? 123 THR A HA   1 
ATOM   1716 H  HB   . THR A 1 112 ? 156.647 162.543 171.976 1.00 77.37  ? 123 THR A HB   1 
ATOM   1717 H  HG1  . THR A 1 112 ? 155.178 163.224 169.867 1.00 78.65  ? 123 THR A HG1  1 
ATOM   1718 H  HG21 . THR A 1 112 ? 158.026 162.096 170.289 1.00 78.53  ? 123 THR A HG21 1 
ATOM   1719 H  HG22 . THR A 1 112 ? 157.278 160.711 170.393 1.00 79.15  ? 123 THR A HG22 1 
ATOM   1720 H  HG23 . THR A 1 112 ? 156.850 161.758 169.294 1.00 78.66  ? 123 THR A HG23 1 
ATOM   1721 N  N    . LYS A 1 113 ? 152.973 160.919 170.375 1.00 77.83  ? 124 LYS A N    1 
ATOM   1722 C  CA   . LYS A 1 113 ? 152.159 160.491 169.243 1.00 74.49  ? 124 LYS A CA   1 
ATOM   1723 C  C    . LYS A 1 113 ? 152.427 161.354 168.017 1.00 67.64  ? 124 LYS A C    1 
ATOM   1724 O  O    . LYS A 1 113 ? 152.502 160.843 166.893 1.00 72.04  ? 124 LYS A O    1 
ATOM   1725 C  CB   . LYS A 1 113 ? 150.678 160.536 169.621 1.00 76.19  ? 124 LYS A CB   1 
ATOM   1726 C  CG   . LYS A 1 113 ? 149.725 160.030 168.540 1.00 78.13  ? 124 LYS A CG   1 
ATOM   1727 C  CD   . LYS A 1 113 ? 149.946 158.559 168.198 1.00 78.32  ? 124 LYS A CD   1 
ATOM   1728 C  CE   . LYS A 1 113 ? 149.571 157.636 169.350 1.00 77.11  ? 124 LYS A CE   1 
ATOM   1729 N  NZ   . LYS A 1 113 ? 148.113 157.677 169.654 1.00 74.63  ? 124 LYS A NZ   1 
ATOM   1730 H  H    . LYS A 1 113 ? 152.527 161.231 171.041 1.00 75.92  ? 124 LYS A H    1 
ATOM   1731 H  HA   . LYS A 1 113 ? 152.390 159.576 169.022 1.00 75.27  ? 124 LYS A HA   1 
ATOM   1732 H  HB2  . LYS A 1 113 ? 150.543 159.998 170.416 1.00 75.11  ? 124 LYS A HB2  1 
ATOM   1733 H  HB3  . LYS A 1 113 ? 150.438 161.456 169.811 1.00 75.11  ? 124 LYS A HB3  1 
ATOM   1734 H  HG2  . LYS A 1 113 ? 148.813 160.131 168.853 1.00 75.14  ? 124 LYS A HG2  1 
ATOM   1735 H  HG3  . LYS A 1 113 ? 149.855 160.550 167.732 1.00 75.50  ? 124 LYS A HG3  1 
ATOM   1736 H  HD2  . LYS A 1 113 ? 149.390 158.326 167.437 1.00 75.15  ? 124 LYS A HD2  1 
ATOM   1737 H  HD3  . LYS A 1 113 ? 150.879 158.411 167.981 1.00 75.03  ? 124 LYS A HD3  1 
ATOM   1738 H  HE2  . LYS A 1 113 ? 149.799 156.725 169.110 1.00 74.95  ? 124 LYS A HE2  1 
ATOM   1739 H  HE3  . LYS A 1 113 ? 150.055 157.898 170.148 1.00 75.25  ? 124 LYS A HE3  1 
ATOM   1740 H  HZ1  . LYS A 1 113 ? 147.646 157.441 168.934 1.00 74.73  ? 124 LYS A HZ1  1 
ATOM   1741 H  HZ2  . LYS A 1 113 ? 147.876 158.499 169.897 1.00 74.89  ? 124 LYS A HZ2  1 
ATOM   1742 H  HZ3  . LYS A 1 113 ? 147.926 157.114 170.318 1.00 74.56  ? 124 LYS A HZ3  1 
ATOM   1743 N  N    . ILE A 1 114 ? 152.574 162.662 168.211 1.00 59.95  ? 125 ILE A N    1 
ATOM   1744 C  CA   . ILE A 1 114 ? 152.838 163.603 167.128 1.00 60.26  ? 125 ILE A CA   1 
ATOM   1745 C  C    . ILE A 1 114 ? 154.140 164.326 167.439 1.00 62.84  ? 125 ILE A C    1 
ATOM   1746 O  O    . ILE A 1 114 ? 154.278 164.944 168.503 1.00 73.16  ? 125 ILE A O    1 
ATOM   1747 C  CB   . ILE A 1 114 ? 151.686 164.603 166.945 1.00 59.31  ? 125 ILE A CB   1 
ATOM   1748 C  CG1  . ILE A 1 114 ? 150.347 163.867 166.910 1.00 65.89  ? 125 ILE A CG1  1 
ATOM   1749 C  CG2  . ILE A 1 114 ? 151.878 165.406 165.673 1.00 60.17  ? 125 ILE A CG2  1 
ATOM   1750 C  CD1  . ILE A 1 114 ? 149.623 163.866 168.233 1.00 71.98  ? 125 ILE A CD1  1 
ATOM   1751 H  H    . ILE A 1 114 ? 152.523 163.037 168.983 1.00 66.96  ? 125 ILE A H    1 
ATOM   1752 H  HA   . ILE A 1 114 ? 152.951 163.117 166.297 1.00 66.10  ? 125 ILE A HA   1 
ATOM   1753 H  HB   . ILE A 1 114 ? 151.683 165.214 167.699 1.00 65.70  ? 125 ILE A HB   1 
ATOM   1754 H  HG12 . ILE A 1 114 ? 149.771 164.295 166.257 1.00 66.24  ? 125 ILE A HG12 1 
ATOM   1755 H  HG13 . ILE A 1 114 ? 150.502 162.945 166.655 1.00 66.64  ? 125 ILE A HG13 1 
ATOM   1756 H  HG21 . ILE A 1 114 ? 151.152 166.045 165.591 1.00 65.41  ? 125 ILE A HG21 1 
ATOM   1757 H  HG22 . ILE A 1 114 ? 152.726 165.874 165.717 1.00 64.87  ? 125 ILE A HG22 1 
ATOM   1758 H  HG23 . ILE A 1 114 ? 151.873 164.801 164.915 1.00 65.54  ? 125 ILE A HG23 1 
ATOM   1759 H  HD11 . ILE A 1 114 ? 148.849 163.286 168.170 1.00 67.54  ? 125 ILE A HD11 1 
ATOM   1760 H  HD12 . ILE A 1 114 ? 150.224 163.544 168.923 1.00 68.01  ? 125 ILE A HD12 1 
ATOM   1761 H  HD13 . ILE A 1 114 ? 149.344 164.772 168.436 1.00 67.68  ? 125 ILE A HD13 1 
ATOM   1762 N  N    . LEU A 1 115 ? 155.088 164.252 166.509 1.00 67.05  ? 126 LEU A N    1 
ATOM   1763 C  CA   . LEU A 1 115 ? 156.397 164.877 166.647 1.00 65.45  ? 126 LEU A CA   1 
ATOM   1764 C  C    . LEU A 1 115 ? 156.473 166.040 165.668 1.00 60.79  ? 126 LEU A C    1 
ATOM   1765 O  O    . LEU A 1 115 ? 156.498 165.833 164.451 1.00 74.02  ? 126 LEU A O    1 
ATOM   1766 C  CB   . LEU A 1 115 ? 157.508 163.865 166.380 1.00 70.25  ? 126 LEU A CB   1 
ATOM   1767 C  CG   . LEU A 1 115 ? 158.912 164.425 166.142 1.00 71.60  ? 126 LEU A CG   1 
ATOM   1768 C  CD1  . LEU A 1 115 ? 159.387 165.262 167.322 1.00 74.36  ? 126 LEU A CD1  1 
ATOM   1769 C  CD2  . LEU A 1 115 ? 159.881 163.292 165.858 1.00 69.88  ? 126 LEU A CD2  1 
ATOM   1770 H  H    . LEU A 1 115 ? 154.991 163.829 165.766 1.00 69.95  ? 126 LEU A H    1 
ATOM   1771 H  HA   . LEU A 1 115 ? 156.501 165.222 167.547 1.00 70.32  ? 126 LEU A HA   1 
ATOM   1772 H  HB2  . LEU A 1 115 ? 157.562 163.268 167.143 1.00 70.96  ? 126 LEU A HB2  1 
ATOM   1773 H  HB3  . LEU A 1 115 ? 157.267 163.354 165.591 1.00 69.67  ? 126 LEU A HB3  1 
ATOM   1774 H  HG   . LEU A 1 115 ? 158.897 164.997 165.359 1.00 69.75  ? 126 LEU A HG   1 
ATOM   1775 H  HD11 . LEU A 1 115 ? 160.185 165.745 167.062 1.00 71.77  ? 126 LEU A HD11 1 
ATOM   1776 H  HD12 . LEU A 1 115 ? 158.691 165.888 167.573 1.00 71.44  ? 126 LEU A HD12 1 
ATOM   1777 H  HD13 . LEU A 1 115 ? 159.585 164.671 168.066 1.00 71.69  ? 126 LEU A HD13 1 
ATOM   1778 H  HD21 . LEU A 1 115 ? 160.777 163.655 165.776 1.00 69.91  ? 126 LEU A HD21 1 
ATOM   1779 H  HD22 . LEU A 1 115 ? 159.844 162.656 166.589 1.00 71.02  ? 126 LEU A HD22 1 
ATOM   1780 H  HD23 . LEU A 1 115 ? 159.622 162.858 165.030 1.00 69.99  ? 126 LEU A HD23 1 
ATOM   1781 N  N    . TYR A 1 116 ? 156.498 167.256 166.192 1.00 67.62  ? 127 TYR A N    1 
ATOM   1782 C  CA   . TYR A 1 116 ? 156.715 168.435 165.376 1.00 72.41  ? 127 TYR A CA   1 
ATOM   1783 C  C    . TYR A 1 116 ? 158.208 168.701 165.260 1.00 70.74  ? 127 TYR A C    1 
ATOM   1784 O  O    . TYR A 1 116 ? 158.980 168.444 166.188 1.00 82.06  ? 127 TYR A O    1 
ATOM   1785 C  CB   . TYR A 1 116 ? 156.007 169.646 165.977 1.00 77.82  ? 127 TYR A CB   1 
ATOM   1786 C  CG   . TYR A 1 116 ? 154.509 169.595 165.817 1.00 71.85  ? 127 TYR A CG   1 
ATOM   1787 C  CD1  . TYR A 1 116 ? 153.753 168.660 166.510 1.00 74.20  ? 127 TYR A CD1  1 
ATOM   1788 C  CD2  . TYR A 1 116 ? 153.850 170.473 164.970 1.00 71.18  ? 127 TYR A CD2  1 
ATOM   1789 C  CE1  . TYR A 1 116 ? 152.386 168.604 166.367 1.00 74.60  ? 127 TYR A CE1  1 
ATOM   1790 C  CE2  . TYR A 1 116 ? 152.484 170.423 164.820 1.00 73.40  ? 127 TYR A CE2  1 
ATOM   1791 C  CZ   . TYR A 1 116 ? 151.756 169.487 165.522 1.00 73.68  ? 127 TYR A CZ   1 
ATOM   1792 O  OH   . TYR A 1 116 ? 150.390 169.433 165.377 1.00 77.53  ? 127 TYR A OH   1 
ATOM   1793 H  H    . TYR A 1 116 ? 156.389 167.426 167.028 1.00 74.36  ? 127 TYR A H    1 
ATOM   1794 H  HA   . TYR A 1 116 ? 156.359 168.283 164.487 1.00 72.50  ? 127 TYR A HA   1 
ATOM   1795 H  HB2  . TYR A 1 116 ? 156.209 169.699 166.924 1.00 75.05  ? 127 TYR A HB2  1 
ATOM   1796 H  HB3  . TYR A 1 116 ? 156.322 170.440 165.521 1.00 73.80  ? 127 TYR A HB3  1 
ATOM   1797 H  HD1  . TYR A 1 116 ? 154.177 168.062 167.082 1.00 74.32  ? 127 TYR A HD1  1 
ATOM   1798 H  HD2  . TYR A 1 116 ? 154.340 171.105 164.496 1.00 73.71  ? 127 TYR A HD2  1 
ATOM   1799 H  HE1  . TYR A 1 116 ? 151.892 167.973 166.839 1.00 73.97  ? 127 TYR A HE1  1 
ATOM   1800 H  HE2  . TYR A 1 116 ? 152.054 171.018 164.250 1.00 74.15  ? 127 TYR A HE2  1 
ATOM   1801 H  HH   . TYR A 1 116 ? 150.077 168.815 165.852 1.00 74.67  ? 127 TYR A HH   1 
ATOM   1802 N  N    . ILE A 1 117 ? 158.608 169.221 164.103 1.00 61.59  ? 128 ILE A N    1 
ATOM   1803 C  CA   . ILE A 1 117 ? 160.017 169.363 163.767 1.00 67.54  ? 128 ILE A CA   1 
ATOM   1804 C  C    . ILE A 1 117 ? 160.195 170.604 162.909 1.00 65.77  ? 128 ILE A C    1 
ATOM   1805 O  O    . ILE A 1 117 ? 159.334 170.948 162.096 1.00 71.36  ? 128 ILE A O    1 
ATOM   1806 C  CB   . ILE A 1 117 ? 160.540 168.106 163.036 1.00 71.35  ? 128 ILE A CB   1 
ATOM   1807 C  CG1  . ILE A 1 117 ? 162.059 168.159 162.911 1.00 79.09  ? 128 ILE A CG1  1 
ATOM   1808 C  CG2  . ILE A 1 117 ? 159.896 167.975 161.662 1.00 73.70  ? 128 ILE A CG2  1 
ATOM   1809 C  CD1  . ILE A 1 117 ? 162.672 166.846 162.508 1.00 80.94  ? 128 ILE A CD1  1 
ATOM   1810 H  H    . ILE A 1 117 ? 158.075 169.501 163.489 1.00 70.68  ? 128 ILE A H    1 
ATOM   1811 H  HA   . ILE A 1 117 ? 160.532 169.478 164.580 1.00 72.70  ? 128 ILE A HA   1 
ATOM   1812 H  HB   . ILE A 1 117 ? 160.302 167.325 163.561 1.00 71.88  ? 128 ILE A HB   1 
ATOM   1813 H  HG12 . ILE A 1 117 ? 162.297 168.822 162.245 1.00 72.63  ? 128 ILE A HG12 1 
ATOM   1814 H  HG13 . ILE A 1 117 ? 162.425 168.405 163.772 1.00 73.30  ? 128 ILE A HG13 1 
ATOM   1815 H  HG21 . ILE A 1 117 ? 160.069 167.084 161.319 1.00 71.29  ? 128 ILE A HG21 1 
ATOM   1816 H  HG22 . ILE A 1 117 ? 158.940 168.116 161.746 1.00 72.04  ? 128 ILE A HG22 1 
ATOM   1817 H  HG23 . ILE A 1 117 ? 160.278 168.638 161.067 1.00 71.41  ? 128 ILE A HG23 1 
ATOM   1818 H  HD11 . ILE A 1 117 ? 163.638 166.936 162.505 1.00 73.29  ? 128 ILE A HD11 1 
ATOM   1819 H  HD12 . ILE A 1 117 ? 162.404 166.168 163.147 1.00 73.11  ? 128 ILE A HD12 1 
ATOM   1820 H  HD13 . ILE A 1 117 ? 162.357 166.609 161.621 1.00 72.62  ? 128 ILE A HD13 1 
ATOM   1821 N  N    . THR A 1 118 ? 161.324 171.280 163.097 1.00 71.79  ? 129 THR A N    1 
ATOM   1822 C  CA   . THR A 1 118 ? 161.677 172.386 162.218 1.00 74.18  ? 129 THR A CA   1 
ATOM   1823 C  C    . THR A 1 118 ? 162.507 171.859 161.060 1.00 74.07  ? 129 THR A C    1 
ATOM   1824 O  O    . THR A 1 118 ? 163.459 171.097 161.287 1.00 75.73  ? 129 THR A O    1 
ATOM   1825 C  CB   . THR A 1 118 ? 162.454 173.467 162.967 1.00 78.32  ? 129 THR A CB   1 
ATOM   1826 O  OG1  . THR A 1 118 ? 162.691 174.578 162.091 1.00 72.05  ? 129 THR A OG1  1 
ATOM   1827 C  CG2  . THR A 1 118 ? 163.789 172.938 163.475 1.00 80.21  ? 129 THR A CG2  1 
ATOM   1828 H  H    . THR A 1 118 ? 161.892 171.120 163.722 1.00 75.34  ? 129 THR A H    1 
ATOM   1829 H  HA   . THR A 1 118 ? 160.865 172.783 161.869 1.00 74.86  ? 129 THR A HA   1 
ATOM   1830 H  HB   . THR A 1 118 ? 161.935 173.766 163.729 1.00 75.82  ? 129 THR A HB   1 
ATOM   1831 H  HG1  . THR A 1 118 ? 163.128 175.172 162.492 1.00 75.61  ? 129 THR A HG1  1 
ATOM   1832 H  HG21 . THR A 1 118 ? 164.168 173.561 164.114 1.00 76.57  ? 129 THR A HG21 1 
ATOM   1833 H  HG22 . THR A 1 118 ? 163.670 172.079 163.907 1.00 75.98  ? 129 THR A HG22 1 
ATOM   1834 H  HG23 . THR A 1 118 ? 164.408 172.835 162.736 1.00 76.42  ? 129 THR A HG23 1 
ATOM   1835 N  N    . PRO A 1 119 ? 162.181 172.220 159.818 1.00 68.72  ? 130 PRO A N    1 
ATOM   1836 C  CA   . PRO A 1 119 ? 162.853 171.574 158.680 1.00 72.23  ? 130 PRO A CA   1 
ATOM   1837 C  C    . PRO A 1 119 ? 164.360 171.751 158.680 1.00 71.75  ? 130 PRO A C    1 
ATOM   1838 O  O    . PRO A 1 119 ? 165.088 170.824 158.304 1.00 63.78  ? 130 PRO A O    1 
ATOM   1839 C  CB   . PRO A 1 119 ? 162.195 172.251 157.473 1.00 64.42  ? 130 PRO A CB   1 
ATOM   1840 C  CG   . PRO A 1 119 ? 161.763 173.576 157.974 1.00 67.02  ? 130 PRO A CG   1 
ATOM   1841 C  CD   . PRO A 1 119 ? 161.323 173.335 159.385 1.00 68.24  ? 130 PRO A CD   1 
ATOM   1842 H  HA   . PRO A 1 119 ? 162.645 170.626 158.667 1.00 68.61  ? 130 PRO A HA   1 
ATOM   1843 H  HB2  . PRO A 1 119 ? 162.835 172.335 156.751 1.00 67.78  ? 130 PRO A HB2  1 
ATOM   1844 H  HB3  . PRO A 1 119 ? 161.423 171.735 157.197 1.00 67.10  ? 130 PRO A HB3  1 
ATOM   1845 H  HG2  . PRO A 1 119 ? 162.510 174.193 157.950 1.00 68.33  ? 130 PRO A HG2  1 
ATOM   1846 H  HG3  . PRO A 1 119 ? 161.026 173.905 157.435 1.00 68.01  ? 130 PRO A HG3  1 
ATOM   1847 H  HD2  . PRO A 1 119 ? 161.480 174.120 159.931 1.00 68.33  ? 130 PRO A HD2  1 
ATOM   1848 H  HD3  . PRO A 1 119 ? 160.393 173.064 159.402 1.00 69.12  ? 130 PRO A HD3  1 
ATOM   1849 N  N    . GLU A 1 120 ? 164.854 172.918 159.098 1.00 83.57  ? 131 GLU A N    1 
ATOM   1850 C  CA   . GLU A 1 120 ? 166.288 173.178 159.022 1.00 80.85  ? 131 GLU A CA   1 
ATOM   1851 C  C    . GLU A 1 120 ? 167.069 172.179 159.864 1.00 81.53  ? 131 GLU A C    1 
ATOM   1852 O  O    . GLU A 1 120 ? 168.082 171.630 159.415 1.00 85.34  ? 131 GLU A O    1 
ATOM   1853 C  CB   . GLU A 1 120 ? 166.582 174.611 159.468 1.00 85.11  ? 131 GLU A CB   1 
ATOM   1854 C  CG   . GLU A 1 120 ? 168.057 174.984 159.441 1.00 84.26  ? 131 GLU A CG   1 
ATOM   1855 C  CD   . GLU A 1 120 ? 168.683 174.792 158.073 1.00 86.34  ? 131 GLU A CD   1 
ATOM   1856 O  OE1  . GLU A 1 120 ? 168.383 175.592 157.162 1.00 86.12  ? 131 GLU A OE1  1 
ATOM   1857 O  OE2  . GLU A 1 120 ? 169.474 173.840 157.908 1.00 88.78  ? 131 GLU A OE2  1 
ATOM   1858 H  H    . GLU A 1 120 ? 164.389 173.562 159.426 1.00 83.41  ? 131 GLU A H    1 
ATOM   1859 H  HA   . GLU A 1 120 ? 166.575 173.083 158.101 1.00 83.33  ? 131 GLU A HA   1 
ATOM   1860 H  HB2  . GLU A 1 120 ? 166.113 175.221 158.877 1.00 83.89  ? 131 GLU A HB2  1 
ATOM   1861 H  HB3  . GLU A 1 120 ? 166.264 174.726 160.377 1.00 84.05  ? 131 GLU A HB3  1 
ATOM   1862 H  HG2  . GLU A 1 120 ? 168.149 175.919 159.682 1.00 83.95  ? 131 GLU A HG2  1 
ATOM   1863 H  HG3  . GLU A 1 120 ? 168.540 174.430 160.074 1.00 84.05  ? 131 GLU A HG3  1 
ATOM   1864 N  N    . MET A 1 121 ? 166.614 171.928 161.093 1.00 89.27  ? 132 MET A N    1 
ATOM   1865 C  CA   . MET A 1 121 ? 167.282 170.942 161.933 1.00 93.40  ? 132 MET A CA   1 
ATOM   1866 C  C    . MET A 1 121 ? 166.914 169.522 161.523 1.00 94.72  ? 132 MET A C    1 
ATOM   1867 O  O    . MET A 1 121 ? 167.674 168.587 161.797 1.00 93.71  ? 132 MET A O    1 
ATOM   1868 C  CB   . MET A 1 121 ? 166.944 171.189 163.408 1.00 90.85  ? 132 MET A CB   1 
ATOM   1869 C  CG   . MET A 1 121 ? 167.356 170.065 164.367 1.00 91.29  ? 132 MET A CG   1 
ATOM   1870 S  SD   . MET A 1 121 ? 166.262 168.630 164.441 1.00 88.21  ? 132 MET A SD   1 
ATOM   1871 C  CE   . MET A 1 121 ? 164.685 169.416 164.737 1.00 85.81  ? 132 MET A CE   1 
ATOM   1872 H  H    . MET A 1 121 ? 165.934 172.308 161.454 1.00 88.27  ? 132 MET A H    1 
ATOM   1873 H  HA   . MET A 1 121 ? 168.240 171.051 161.833 1.00 89.04  ? 132 MET A HA   1 
ATOM   1874 H  HB2  . MET A 1 121 ? 167.398 171.996 163.695 1.00 88.54  ? 132 MET A HB2  1 
ATOM   1875 H  HB3  . MET A 1 121 ? 165.987 171.313 163.486 1.00 88.96  ? 132 MET A HB3  1 
ATOM   1876 H  HG2  . MET A 1 121 ? 168.233 169.745 164.103 1.00 89.59  ? 132 MET A HG2  1 
ATOM   1877 H  HG3  . MET A 1 121 ? 167.406 170.434 165.263 1.00 88.84  ? 132 MET A HG3  1 
ATOM   1878 H  HE1  . MET A 1 121 ? 164.093 168.777 165.164 1.00 87.62  ? 132 MET A HE1  1 
ATOM   1879 H  HE2  . MET A 1 121 ? 164.821 170.180 165.318 1.00 88.21  ? 132 MET A HE2  1 
ATOM   1880 H  HE3  . MET A 1 121 ? 164.312 169.706 163.890 1.00 87.65  ? 132 MET A HE3  1 
ATOM   1881 N  N    . ALA A 1 122 ? 165.763 169.339 160.869 1.00 85.62  ? 133 ALA A N    1 
ATOM   1882 C  CA   . ALA A 1 122 ? 165.425 168.023 160.338 1.00 84.23  ? 133 ALA A CA   1 
ATOM   1883 C  C    . ALA A 1 122 ? 166.474 167.549 159.343 1.00 90.73  ? 133 ALA A C    1 
ATOM   1884 O  O    . ALA A 1 122 ? 166.698 166.341 159.204 1.00 89.09  ? 133 ALA A O    1 
ATOM   1885 C  CB   . ALA A 1 122 ? 164.047 168.055 159.678 1.00 77.26  ? 133 ALA A CB   1 
ATOM   1886 H  H    . ALA A 1 122 ? 165.174 169.949 160.723 1.00 83.12  ? 133 ALA A H    1 
ATOM   1887 H  HA   . ALA A 1 122 ? 165.395 167.388 161.069 1.00 84.29  ? 133 ALA A HA   1 
ATOM   1888 H  HB1  . ALA A 1 122 ? 164.074 168.659 158.920 1.00 82.33  ? 133 ALA A HB1  1 
ATOM   1889 H  HB2  . ALA A 1 122 ? 163.393 168.363 160.324 1.00 82.73  ? 133 ALA A HB2  1 
ATOM   1890 H  HB3  . ALA A 1 122 ? 163.822 167.160 159.378 1.00 82.62  ? 133 ALA A HB3  1 
ATOM   1891 N  N    . ALA A 1 123 ? 167.122 168.480 158.645 1.00 96.00  ? 134 ALA A N    1 
ATOM   1892 C  CA   . ALA A 1 123 ? 168.238 168.148 157.771 1.00 89.64  ? 134 ALA A CA   1 
ATOM   1893 C  C    . ALA A 1 123 ? 169.552 168.015 158.527 1.00 87.05  ? 134 ALA A C    1 
ATOM   1894 O  O    . ALA A 1 123 ? 170.544 167.572 157.939 1.00 86.78  ? 134 ALA A O    1 
ATOM   1895 C  CB   . ALA A 1 123 ? 168.382 169.211 156.678 1.00 88.05  ? 134 ALA A CB   1 
ATOM   1896 H  H    . ALA A 1 123 ? 166.931 169.319 158.663 1.00 88.94  ? 134 ALA A H    1 
ATOM   1897 H  HA   . ALA A 1 123 ? 168.056 167.300 157.338 1.00 88.36  ? 134 ALA A HA   1 
ATOM   1898 H  HB1  . ALA A 1 123 ? 169.131 168.979 156.108 1.00 88.86  ? 134 ALA A HB1  1 
ATOM   1899 H  HB2  . ALA A 1 123 ? 167.565 169.240 156.156 1.00 88.27  ? 134 ALA A HB2  1 
ATOM   1900 H  HB3  . ALA A 1 123 ? 168.539 170.073 157.095 1.00 88.69  ? 134 ALA A HB3  1 
ATOM   1901 N  N    . SER A 1 124 ? 169.581 168.384 159.806 1.00 82.23  ? 135 SER A N    1 
ATOM   1902 C  CA   . SER A 1 124 ? 170.811 168.309 160.580 1.00 84.76  ? 135 SER A CA   1 
ATOM   1903 C  C    . SER A 1 124 ? 171.264 166.862 160.720 1.00 85.33  ? 135 SER A C    1 
ATOM   1904 O  O    . SER A 1 124 ? 170.454 165.934 160.784 1.00 80.89  ? 135 SER A O    1 
ATOM   1905 C  CB   . SER A 1 124 ? 170.609 168.932 161.961 1.00 82.77  ? 135 SER A CB   1 
ATOM   1906 O  OG   . SER A 1 124 ? 171.845 169.110 162.630 1.00 76.80  ? 135 SER A OG   1 
ATOM   1907 H  H    . SER A 1 124 ? 168.905 168.680 160.245 1.00 83.82  ? 135 SER A H    1 
ATOM   1908 H  HA   . SER A 1 124 ? 171.508 168.804 160.122 1.00 83.66  ? 135 SER A HA   1 
ATOM   1909 H  HB2  . SER A 1 124 ? 170.181 169.796 161.857 1.00 83.29  ? 135 SER A HB2  1 
ATOM   1910 H  HB3  . SER A 1 124 ? 170.046 168.346 162.492 1.00 83.56  ? 135 SER A HB3  1 
ATOM   1911 H  HG   . SER A 1 124 ? 171.715 169.450 163.387 1.00 82.43  ? 135 SER A HG   1 
ATOM   1912 N  N    . SER A 1 125 ? 172.584 166.675 160.760 1.00 98.46  ? 136 SER A N    1 
ATOM   1913 C  CA   . SER A 1 125 ? 173.135 165.332 160.892 1.00 99.33  ? 136 SER A CA   1 
ATOM   1914 C  C    . SER A 1 125 ? 172.715 164.679 162.203 1.00 104.92 ? 136 SER A C    1 
ATOM   1915 O  O    . SER A 1 125 ? 172.565 163.454 162.264 1.00 101.92 ? 136 SER A O    1 
ATOM   1916 C  CB   . SER A 1 125 ? 174.658 165.382 160.789 1.00 98.61  ? 136 SER A CB   1 
ATOM   1917 O  OG   . SER A 1 125 ? 175.210 166.185 161.818 1.00 98.50  ? 136 SER A OG   1 
ATOM   1918 H  H    . SER A 1 125 ? 173.171 167.301 160.714 1.00 98.50  ? 136 SER A H    1 
ATOM   1919 H  HA   . SER A 1 125 ? 172.803 164.783 160.164 1.00 98.92  ? 136 SER A HA   1 
ATOM   1920 H  HB2  . SER A 1 125 ? 175.010 164.482 160.868 1.00 99.41  ? 136 SER A HB2  1 
ATOM   1921 H  HB3  . SER A 1 125 ? 174.904 165.759 159.929 1.00 99.18  ? 136 SER A HB3  1 
ATOM   1922 H  HG   . SER A 1 125 ? 176.045 166.230 161.732 1.00 99.36  ? 136 SER A HG   1 
ATOM   1923 N  N    . SER A 1 126 ? 172.530 165.474 163.260 1.00 118.68 ? 137 SER A N    1 
ATOM   1924 C  CA   . SER A 1 126 ? 172.170 164.910 164.557 1.00 117.23 ? 137 SER A CA   1 
ATOM   1925 C  C    . SER A 1 126 ? 170.800 164.241 164.514 1.00 114.73 ? 137 SER A C    1 
ATOM   1926 O  O    . SER A 1 126 ? 170.604 163.175 165.109 1.00 110.06 ? 137 SER A O    1 
ATOM   1927 C  CB   . SER A 1 126 ? 172.198 166.001 165.627 1.00 114.83 ? 137 SER A CB   1 
ATOM   1928 O  OG   . SER A 1 126 ? 173.525 166.430 165.881 1.00 114.61 ? 137 SER A OG   1 
ATOM   1929 H  H    . SER A 1 126 ? 172.607 166.331 163.251 1.00 113.11 ? 137 SER A H    1 
ATOM   1930 H  HA   . SER A 1 126 ? 172.823 164.236 164.799 1.00 113.85 ? 137 SER A HA   1 
ATOM   1931 H  HB2  . SER A 1 126 ? 171.677 166.759 165.318 1.00 113.21 ? 137 SER A HB2  1 
ATOM   1932 H  HB3  . SER A 1 126 ? 171.819 165.649 166.447 1.00 113.72 ? 137 SER A HB3  1 
ATOM   1933 H  HG   . SER A 1 126 ? 173.530 166.998 166.500 1.00 113.92 ? 137 SER A HG   1 
ATOM   1934 N  N    . PHE A 1 127 ? 169.834 164.859 163.830 1.00 97.23  ? 138 PHE A N    1 
ATOM   1935 C  CA   . PHE A 1 127 ? 168.496 164.280 163.764 1.00 93.73  ? 138 PHE A CA   1 
ATOM   1936 C  C    . PHE A 1 127 ? 168.454 163.033 162.890 1.00 94.77  ? 138 PHE A C    1 
ATOM   1937 O  O    . PHE A 1 127 ? 167.665 162.120 163.160 1.00 91.16  ? 138 PHE A O    1 
ATOM   1938 C  CB   . PHE A 1 127 ? 167.497 165.311 163.241 1.00 93.95  ? 138 PHE A CB   1 
ATOM   1939 C  CG   . PHE A 1 127 ? 166.114 164.759 163.034 1.00 96.60  ? 138 PHE A CG   1 
ATOM   1940 C  CD1  . PHE A 1 127 ? 165.376 164.278 164.103 1.00 92.72  ? 138 PHE A CD1  1 
ATOM   1941 C  CD2  . PHE A 1 127 ? 165.554 164.719 161.769 1.00 97.78  ? 138 PHE A CD2  1 
ATOM   1942 C  CE1  . PHE A 1 127 ? 164.106 163.768 163.912 1.00 92.72  ? 138 PHE A CE1  1 
ATOM   1943 C  CE2  . PHE A 1 127 ? 164.284 164.213 161.574 1.00 93.52  ? 138 PHE A CE2  1 
ATOM   1944 C  CZ   . PHE A 1 127 ? 163.561 163.734 162.646 1.00 91.56  ? 138 PHE A CZ   1 
ATOM   1945 H  H    . PHE A 1 127 ? 169.927 165.601 163.406 1.00 94.20  ? 138 PHE A H    1 
ATOM   1946 H  HA   . PHE A 1 127 ? 168.220 164.026 164.658 1.00 93.43  ? 138 PHE A HA   1 
ATOM   1947 H  HB2  . PHE A 1 127 ? 167.434 166.038 163.880 1.00 92.70  ? 138 PHE A HB2  1 
ATOM   1948 H  HB3  . PHE A 1 127 ? 167.812 165.648 162.388 1.00 93.04  ? 138 PHE A HB3  1 
ATOM   1949 H  HD1  . PHE A 1 127 ? 165.740 164.297 164.958 1.00 92.85  ? 138 PHE A HD1  1 
ATOM   1950 H  HD2  . PHE A 1 127 ? 166.038 165.039 161.042 1.00 93.31  ? 138 PHE A HD2  1 
ATOM   1951 H  HE1  . PHE A 1 127 ? 163.620 163.448 164.637 1.00 92.79  ? 138 PHE A HE1  1 
ATOM   1952 H  HE2  . PHE A 1 127 ? 163.919 164.190 160.718 1.00 92.55  ? 138 PHE A HE2  1 
ATOM   1953 H  HZ   . PHE A 1 127 ? 162.706 163.393 162.516 1.00 92.05  ? 138 PHE A HZ   1 
ATOM   1954 N  N    . GLN A 1 128 ? 169.281 162.975 161.849 1.00 95.88  ? 139 GLN A N    1 
ATOM   1955 C  CA   . GLN A 1 128 ? 169.192 161.882 160.885 1.00 94.86  ? 139 GLN A CA   1 
ATOM   1956 C  C    . GLN A 1 128 ? 169.239 160.495 161.514 1.00 94.01  ? 139 GLN A C    1 
ATOM   1957 O  O    . GLN A 1 128 ? 168.461 159.630 161.078 1.00 91.44  ? 139 GLN A O    1 
ATOM   1958 C  CB   . GLN A 1 128 ? 170.305 162.029 159.837 1.00 93.04  ? 139 GLN A CB   1 
ATOM   1959 C  CG   . GLN A 1 128 ? 169.932 162.915 158.653 1.00 94.28  ? 139 GLN A CG   1 
ATOM   1960 C  CD   . GLN A 1 128 ? 168.703 162.420 157.911 1.00 95.57  ? 139 GLN A CD   1 
ATOM   1961 O  OE1  . GLN A 1 128 ? 168.288 161.272 158.071 1.00 95.50  ? 139 GLN A OE1  1 
ATOM   1962 N  NE2  . GLN A 1 128 ? 168.112 163.288 157.098 1.00 93.41  ? 139 GLN A NE2  1 
ATOM   1963 H  H    . GLN A 1 128 ? 169.896 163.551 161.679 1.00 94.23  ? 139 GLN A H    1 
ATOM   1964 H  HA   . GLN A 1 128 ? 168.339 161.956 160.430 1.00 94.23  ? 139 GLN A HA   1 
ATOM   1965 H  HB2  . GLN A 1 128 ? 171.085 162.418 160.262 1.00 94.05  ? 139 GLN A HB2  1 
ATOM   1966 H  HB3  . GLN A 1 128 ? 170.524 161.150 159.491 1.00 93.58  ? 139 GLN A HB3  1 
ATOM   1967 H  HG2  . GLN A 1 128 ? 169.748 163.812 158.972 1.00 93.80  ? 139 GLN A HG2  1 
ATOM   1968 H  HG3  . GLN A 1 128 ? 170.672 162.931 158.026 1.00 93.83  ? 139 GLN A HG3  1 
ATOM   1969 H  HE21 . GLN A 1 128 ? 168.429 164.082 157.012 1.00 93.68  ? 139 GLN A HE21 1 
ATOM   1970 H  HE22 . GLN A 1 128 ? 167.411 163.055 156.657 1.00 93.54  ? 139 GLN A HE22 1 
ATOM   1971 N  N    . PRO A 1 129 ? 170.110 160.195 162.484 1.00 94.88  ? 140 PRO A N    1 
ATOM   1972 C  CA   . PRO A 1 129 ? 170.021 158.869 163.122 1.00 93.79  ? 140 PRO A CA   1 
ATOM   1973 C  C    . PRO A 1 129 ? 168.656 158.600 163.730 1.00 93.70  ? 140 PRO A C    1 
ATOM   1974 O  O    . PRO A 1 129 ? 168.116 157.496 163.580 1.00 93.19  ? 140 PRO A O    1 
ATOM   1975 C  CB   . PRO A 1 129 ? 171.134 158.913 164.181 1.00 92.62  ? 140 PRO A CB   1 
ATOM   1976 C  CG   . PRO A 1 129 ? 171.433 160.359 164.380 1.00 89.47  ? 140 PRO A CG   1 
ATOM   1977 C  CD   . PRO A 1 129 ? 171.215 160.990 163.044 1.00 91.23  ? 140 PRO A CD   1 
ATOM   1978 H  HA   . PRO A 1 129 ? 170.232 158.177 162.478 1.00 92.67  ? 140 PRO A HA   1 
ATOM   1979 H  HB2  . PRO A 1 129 ? 170.816 158.512 165.005 1.00 92.76  ? 140 PRO A HB2  1 
ATOM   1980 H  HB3  . PRO A 1 129 ? 171.916 158.443 163.851 1.00 92.70  ? 140 PRO A HB3  1 
ATOM   1981 H  HG2  . PRO A 1 129 ? 170.826 160.729 165.038 1.00 92.28  ? 140 PRO A HG2  1 
ATOM   1982 H  HG3  . PRO A 1 129 ? 172.355 160.466 164.663 1.00 92.26  ? 140 PRO A HG3  1 
ATOM   1983 H  HD2  . PRO A 1 129 ? 170.961 161.915 163.153 1.00 93.00  ? 140 PRO A HD2  1 
ATOM   1984 H  HD3  . PRO A 1 129 ? 172.009 160.901 162.494 1.00 92.71  ? 140 PRO A HD3  1 
ATOM   1985 N  N    . THR A 1 130 ? 168.059 159.595 164.385 1.00 93.78  ? 141 THR A N    1 
ATOM   1986 C  CA   . THR A 1 130 ? 166.709 159.416 164.906 1.00 92.19  ? 141 THR A CA   1 
ATOM   1987 C  C    . THR A 1 130 ? 165.715 159.201 163.773 1.00 85.43  ? 141 THR A C    1 
ATOM   1988 O  O    . THR A 1 130 ? 164.823 158.349 163.869 1.00 86.64  ? 141 THR A O    1 
ATOM   1989 C  CB   . THR A 1 130 ? 166.308 160.626 165.752 1.00 91.83  ? 141 THR A CB   1 
ATOM   1990 O  OG1  . THR A 1 130 ? 167.381 160.970 166.638 1.00 88.38  ? 141 THR A OG1  1 
ATOM   1991 C  CG2  . THR A 1 130 ? 165.061 160.319 166.569 1.00 94.37  ? 141 THR A CG2  1 
ATOM   1992 H  H    . THR A 1 130 ? 168.406 160.367 164.538 1.00 91.00  ? 141 THR A H    1 
ATOM   1993 H  HA   . THR A 1 130 ? 166.691 158.631 165.476 1.00 90.93  ? 141 THR A HA   1 
ATOM   1994 H  HB   . THR A 1 130 ? 166.117 161.377 165.170 1.00 90.12  ? 141 THR A HB   1 
ATOM   1995 H  HG1  . THR A 1 130 ? 167.170 161.640 167.098 1.00 90.78  ? 141 THR A HG1  1 
ATOM   1996 H  HG21 . THR A 1 130 ? 164.839 161.077 167.132 1.00 91.39  ? 141 THR A HG21 1 
ATOM   1997 H  HG22 . THR A 1 130 ? 164.314 160.136 165.978 1.00 90.97  ? 141 THR A HG22 1 
ATOM   1998 H  HG23 . THR A 1 130 ? 165.216 159.544 167.131 1.00 90.77  ? 141 THR A HG23 1 
ATOM   1999 N  N    . LEU A 1 131 ? 165.863 159.955 162.682 1.00 74.48  ? 142 LEU A N    1 
ATOM   2000 C  CA   . LEU A 1 131 ? 164.923 159.845 161.572 1.00 80.95  ? 142 LEU A CA   1 
ATOM   2001 C  C    . LEU A 1 131 ? 164.954 158.451 160.959 1.00 83.93  ? 142 LEU A C    1 
ATOM   2002 O  O    . LEU A 1 131 ? 163.905 157.833 160.741 1.00 81.72  ? 142 LEU A O    1 
ATOM   2003 C  CB   . LEU A 1 131 ? 165.241 160.902 160.515 1.00 86.19  ? 142 LEU A CB   1 
ATOM   2004 C  CG   . LEU A 1 131 ? 164.305 160.946 159.306 1.00 87.37  ? 142 LEU A CG   1 
ATOM   2005 C  CD1  . LEU A 1 131 ? 162.869 161.211 159.740 1.00 83.35  ? 142 LEU A CD1  1 
ATOM   2006 C  CD2  . LEU A 1 131 ? 164.769 162.000 158.315 1.00 82.17  ? 142 LEU A CD2  1 
ATOM   2007 H  H    . LEU A 1 131 ? 166.491 160.529 162.564 1.00 82.72  ? 142 LEU A H    1 
ATOM   2008 H  HA   . LEU A 1 131 ? 164.026 160.007 161.903 1.00 82.15  ? 142 LEU A HA   1 
ATOM   2009 H  HB2  . LEU A 1 131 ? 165.215 161.773 160.937 1.00 83.54  ? 142 LEU A HB2  1 
ATOM   2010 H  HB3  . LEU A 1 131 ? 166.136 160.735 160.180 1.00 83.46  ? 142 LEU A HB3  1 
ATOM   2011 H  HG   . LEU A 1 131 ? 164.326 160.086 158.857 1.00 83.21  ? 142 LEU A HG   1 
ATOM   2012 H  HD11 . LEU A 1 131 ? 162.325 161.365 158.952 1.00 82.13  ? 142 LEU A HD11 1 
ATOM   2013 H  HD12 . LEU A 1 131 ? 162.537 160.440 160.225 1.00 82.09  ? 142 LEU A HD12 1 
ATOM   2014 H  HD13 . LEU A 1 131 ? 162.853 161.995 160.311 1.00 82.42  ? 142 LEU A HD13 1 
ATOM   2015 H  HD21 . LEU A 1 131 ? 164.151 162.026 157.569 1.00 82.26  ? 142 LEU A HD21 1 
ATOM   2016 H  HD22 . LEU A 1 131 ? 164.789 162.862 158.759 1.00 82.73  ? 142 LEU A HD22 1 
ATOM   2017 H  HD23 . LEU A 1 131 ? 165.658 161.769 158.002 1.00 82.26  ? 142 LEU A HD23 1 
ATOM   2018 N  N    . ASN A 1 132 ? 166.150 157.932 160.669 1.00 85.63  ? 143 ASN A N    1 
ATOM   2019 C  CA   . ASN A 1 132 ? 166.220 156.621 160.034 1.00 83.61  ? 143 ASN A CA   1 
ATOM   2020 C  C    . ASN A 1 132 ? 165.923 155.499 161.020 1.00 81.67  ? 143 ASN A C    1 
ATOM   2021 O  O    . ASN A 1 132 ? 165.455 154.433 160.605 1.00 81.19  ? 143 ASN A O    1 
ATOM   2022 C  CB   . ASN A 1 132 ? 167.584 156.407 159.368 1.00 84.27  ? 143 ASN A CB   1 
ATOM   2023 C  CG   . ASN A 1 132 ? 168.702 156.213 160.364 1.00 84.71  ? 143 ASN A CG   1 
ATOM   2024 O  OD1  . ASN A 1 132 ? 168.696 156.802 161.435 1.00 81.45  ? 143 ASN A OD1  1 
ATOM   2025 N  ND2  . ASN A 1 132 ? 169.677 155.384 160.009 1.00 88.18  ? 143 ASN A ND2  1 
ATOM   2026 H  H    . ASN A 1 132 ? 166.909 158.306 160.824 1.00 84.24  ? 143 ASN A H    1 
ATOM   2027 H  HA   . ASN A 1 132 ? 165.548 156.581 159.336 1.00 83.84  ? 143 ASN A HA   1 
ATOM   2028 H  HB2  . ASN A 1 132 ? 167.541 155.614 158.810 1.00 83.90  ? 143 ASN A HB2  1 
ATOM   2029 H  HB3  . ASN A 1 132 ? 167.796 157.182 158.826 1.00 83.82  ? 143 ASN A HB3  1 
ATOM   2030 H  HD21 . ASN A 1 132 ? 169.649 154.988 159.246 1.00 84.36  ? 143 ASN A HD21 1 
ATOM   2031 H  HD22 . ASN A 1 132 ? 170.336 155.244 160.543 1.00 84.23  ? 143 ASN A HD22 1 
ATOM   2032 N  N    . SER A 1 133 ? 166.159 155.709 162.320 1.00 87.31  ? 144 SER A N    1 
ATOM   2033 C  CA   . SER A 1 133 ? 165.675 154.747 163.303 1.00 88.12  ? 144 SER A CA   1 
ATOM   2034 C  C    . SER A 1 133 ? 164.153 154.685 163.290 1.00 88.58  ? 144 SER A C    1 
ATOM   2035 O  O    . SER A 1 133 ? 163.564 153.600 163.371 1.00 87.29  ? 144 SER A O    1 
ATOM   2036 C  CB   . SER A 1 133 ? 166.185 155.114 164.696 1.00 86.36  ? 144 SER A CB   1 
ATOM   2037 O  OG   . SER A 1 133 ? 165.749 154.172 165.661 1.00 82.61  ? 144 SER A OG   1 
ATOM   2038 H  H    . SER A 1 133 ? 166.582 156.383 162.647 1.00 87.06  ? 144 SER A H    1 
ATOM   2039 H  HA   . SER A 1 133 ? 166.015 153.866 163.079 1.00 86.94  ? 144 SER A HA   1 
ATOM   2040 H  HB2  . SER A 1 133 ? 167.155 155.130 164.685 1.00 86.87  ? 144 SER A HB2  1 
ATOM   2041 H  HB3  . SER A 1 133 ? 165.842 155.990 164.935 1.00 86.29  ? 144 SER A HB3  1 
ATOM   2042 H  HG   . SER A 1 133 ? 166.021 154.396 166.424 1.00 85.79  ? 144 SER A HG   1 
ATOM   2043 N  N    . LEU A 1 134 ? 163.500 155.844 163.188 1.00 90.53  ? 145 LEU A N    1 
ATOM   2044 C  CA   . LEU A 1 134 ? 162.048 155.872 163.055 1.00 90.56  ? 145 LEU A CA   1 
ATOM   2045 C  C    . LEU A 1 134 ? 161.610 155.157 161.783 1.00 88.97  ? 145 LEU A C    1 
ATOM   2046 O  O    . LEU A 1 134 ? 160.649 154.378 161.789 1.00 88.07  ? 145 LEU A O    1 
ATOM   2047 C  CB   . LEU A 1 134 ? 161.555 157.322 163.049 1.00 87.25  ? 145 LEU A CB   1 
ATOM   2048 C  CG   . LEU A 1 134 ? 161.000 157.895 164.353 1.00 86.70  ? 145 LEU A CG   1 
ATOM   2049 C  CD1  . LEU A 1 134 ? 162.081 157.982 165.412 1.00 85.36  ? 145 LEU A CD1  1 
ATOM   2050 C  CD2  . LEU A 1 134 ? 160.398 159.269 164.103 1.00 86.46  ? 145 LEU A CD2  1 
ATOM   2051 H  H    . LEU A 1 134 ? 163.875 156.618 163.190 1.00 86.33  ? 145 LEU A H    1 
ATOM   2052 H  HA   . LEU A 1 134 ? 161.648 155.416 163.812 1.00 86.14  ? 145 LEU A HA   1 
ATOM   2053 H  HB2  . LEU A 1 134 ? 162.293 157.891 162.780 1.00 85.73  ? 145 LEU A HB2  1 
ATOM   2054 H  HB3  . LEU A 1 134 ? 160.847 157.390 162.389 1.00 86.27  ? 145 LEU A HB3  1 
ATOM   2055 H  HG   . LEU A 1 134 ? 160.298 157.313 164.684 1.00 86.03  ? 145 LEU A HG   1 
ATOM   2056 H  HD11 . LEU A 1 134 ? 161.667 158.161 166.270 1.00 85.30  ? 145 LEU A HD11 1 
ATOM   2057 H  HD12 . LEU A 1 134 ? 162.561 157.141 165.443 1.00 85.55  ? 145 LEU A HD12 1 
ATOM   2058 H  HD13 . LEU A 1 134 ? 162.689 158.701 165.181 1.00 86.15  ? 145 LEU A HD13 1 
ATOM   2059 H  HD21 . LEU A 1 134 ? 160.099 159.641 164.947 1.00 85.60  ? 145 LEU A HD21 1 
ATOM   2060 H  HD22 . LEU A 1 134 ? 161.075 159.844 163.711 1.00 85.31  ? 145 LEU A HD22 1 
ATOM   2061 H  HD23 . LEU A 1 134 ? 159.648 159.180 163.495 1.00 85.16  ? 145 LEU A HD23 1 
ATOM   2062 N  N    . VAL A 1 135 ? 162.310 155.414 160.677 1.00 73.18  ? 146 VAL A N    1 
ATOM   2063 C  CA   . VAL A 1 135 ? 161.927 154.828 159.396 1.00 71.76  ? 146 VAL A CA   1 
ATOM   2064 C  C    . VAL A 1 135 ? 162.044 153.310 159.444 1.00 77.77  ? 146 VAL A C    1 
ATOM   2065 O  O    . VAL A 1 135 ? 161.154 152.590 158.977 1.00 79.40  ? 146 VAL A O    1 
ATOM   2066 C  CB   . VAL A 1 135 ? 162.783 155.422 158.262 1.00 73.25  ? 146 VAL A CB   1 
ATOM   2067 C  CG1  . VAL A 1 135 ? 162.476 154.725 156.940 1.00 70.85  ? 146 VAL A CG1  1 
ATOM   2068 C  CG2  . VAL A 1 135 ? 162.554 156.921 158.153 1.00 72.10  ? 146 VAL A CG2  1 
ATOM   2069 H  H    . VAL A 1 135 ? 163.004 155.922 160.644 1.00 74.47  ? 146 VAL A H    1 
ATOM   2070 H  HA   . VAL A 1 135 ? 161.000 155.048 159.215 1.00 73.22  ? 146 VAL A HA   1 
ATOM   2071 H  HB   . VAL A 1 135 ? 163.720 155.277 158.468 1.00 73.92  ? 146 VAL A HB   1 
ATOM   2072 H  HG11 . VAL A 1 135 ? 162.874 155.232 156.215 1.00 72.98  ? 146 VAL A HG11 1 
ATOM   2073 H  HG12 . VAL A 1 135 ? 162.850 153.832 156.958 1.00 73.20  ? 146 VAL A HG12 1 
ATOM   2074 H  HG13 . VAL A 1 135 ? 161.515 154.682 156.825 1.00 72.99  ? 146 VAL A HG13 1 
ATOM   2075 H  HG21 . VAL A 1 135 ? 162.375 157.151 157.228 1.00 73.64  ? 146 VAL A HG21 1 
ATOM   2076 H  HG22 . VAL A 1 135 ? 161.795 157.162 158.707 1.00 73.46  ? 146 VAL A HG22 1 
ATOM   2077 H  HG23 . VAL A 1 135 ? 163.348 157.384 158.462 1.00 73.77  ? 146 VAL A HG23 1 
ATOM   2078 N  N    . SER A 1 136 ? 163.143 152.800 160.004 1.00 79.74  ? 147 SER A N    1 
ATOM   2079 C  CA   . SER A 1 136 ? 163.365 151.357 160.012 1.00 81.27  ? 147 SER A CA   1 
ATOM   2080 C  C    . SER A 1 136 ? 162.305 150.636 160.835 1.00 81.19  ? 147 SER A C    1 
ATOM   2081 O  O    . SER A 1 136 ? 161.829 149.564 160.443 1.00 76.26  ? 147 SER A O    1 
ATOM   2082 C  CB   . SER A 1 136 ? 164.760 151.049 160.552 1.00 79.83  ? 147 SER A CB   1 
ATOM   2083 O  OG   . SER A 1 136 ? 164.864 149.694 160.949 1.00 80.34  ? 147 SER A OG   1 
ATOM   2084 H  H    . SER A 1 136 ? 163.765 153.260 160.380 1.00 79.01  ? 147 SER A H    1 
ATOM   2085 H  HA   . SER A 1 136 ? 163.315 151.024 159.103 1.00 79.90  ? 147 SER A HA   1 
ATOM   2086 H  HB2  . SER A 1 136 ? 165.410 151.224 159.854 1.00 79.85  ? 147 SER A HB2  1 
ATOM   2087 H  HB3  . SER A 1 136 ? 164.933 151.618 161.318 1.00 79.86  ? 147 SER A HB3  1 
ATOM   2088 H  HG   . SER A 1 136 ? 165.621 149.551 161.286 1.00 79.82  ? 147 SER A HG   1 
ATOM   2089 N  N    . ARG A 1 137 ? 161.924 151.206 161.978 1.00 85.71  ? 148 ARG A N    1 
ATOM   2090 C  CA   . ARG A 1 137 ? 160.961 150.559 162.860 1.00 85.90  ? 148 ARG A CA   1 
ATOM   2091 C  C    . ARG A 1 137 ? 159.537 150.608 162.320 1.00 84.19  ? 148 ARG A C    1 
ATOM   2092 O  O    . ARG A 1 137 ? 158.660 149.951 162.889 1.00 82.82  ? 148 ARG A O    1 
ATOM   2093 C  CB   . ARG A 1 137 ? 161.011 151.210 164.242 1.00 82.01  ? 148 ARG A CB   1 
ATOM   2094 C  CG   . ARG A 1 137 ? 162.283 150.915 165.018 1.00 81.30  ? 148 ARG A CG   1 
ATOM   2095 C  CD   . ARG A 1 137 ? 162.247 151.566 166.385 1.00 83.50  ? 148 ARG A CD   1 
ATOM   2096 N  NE   . ARG A 1 137 ? 162.550 152.991 166.321 1.00 83.42  ? 148 ARG A NE   1 
ATOM   2097 C  CZ   . ARG A 1 137 ? 162.376 153.838 167.326 1.00 87.64  ? 148 ARG A CZ   1 
ATOM   2098 N  NH1  . ARG A 1 137 ? 161.873 153.443 168.485 1.00 90.24  ? 148 ARG A NH1  1 
ATOM   2099 N  NH2  . ARG A 1 137 ? 162.708 155.115 167.163 1.00 87.22  ? 148 ARG A NH2  1 
ATOM   2100 H  H    . ARG A 1 137 ? 162.208 151.966 162.262 1.00 83.95  ? 148 ARG A H    1 
ATOM   2101 H  HA   . ARG A 1 137 ? 161.208 149.626 162.961 1.00 84.67  ? 148 ARG A HA   1 
ATOM   2102 H  HB2  . ARG A 1 137 ? 160.944 152.172 164.137 1.00 83.63  ? 148 ARG A HB2  1 
ATOM   2103 H  HB3  . ARG A 1 137 ? 160.264 150.883 164.766 1.00 84.32  ? 148 ARG A HB3  1 
ATOM   2104 H  HG2  . ARG A 1 137 ? 162.369 149.957 165.139 1.00 84.28  ? 148 ARG A HG2  1 
ATOM   2105 H  HG3  . ARG A 1 137 ? 163.046 151.265 164.532 1.00 83.92  ? 148 ARG A HG3  1 
ATOM   2106 H  HD2  . ARG A 1 137 ? 161.362 151.460 166.765 1.00 84.64  ? 148 ARG A HD2  1 
ATOM   2107 H  HD3  . ARG A 1 137 ? 162.907 151.144 166.955 1.00 84.71  ? 148 ARG A HD3  1 
ATOM   2108 H  HE   . ARG A 1 137 ? 162.838 153.308 165.576 1.00 84.13  ? 148 ARG A HE   1 
ATOM   2109 H  HH11 . ARG A 1 137 ? 161.653 152.621 168.603 1.00 85.53  ? 148 ARG A HH11 1 
ATOM   2110 H  HH12 . ARG A 1 137 ? 161.766 154.012 169.120 1.00 85.42  ? 148 ARG A HH12 1 
ATOM   2111 H  HH21 . ARG A 1 137 ? 163.035 155.381 166.414 1.00 84.52  ? 148 ARG A HH21 1 
ATOM   2112 H  HH22 . ARG A 1 137 ? 162.598 155.675 167.808 1.00 85.00  ? 148 ARG A HH22 1 
ATOM   2113 N  N    . HIS A 1 138 ? 159.288 151.363 161.250 1.00 77.24  ? 149 HIS A N    1 
ATOM   2114 C  CA   . HIS A 1 138 ? 157.947 151.522 160.688 1.00 72.44  ? 149 HIS A CA   1 
ATOM   2115 C  C    . HIS A 1 138 ? 157.006 152.216 161.668 1.00 71.18  ? 149 HIS A C    1 
ATOM   2116 O  O    . HIS A 1 138 ? 155.786 152.054 161.595 1.00 70.39  ? 149 HIS A O    1 
ATOM   2117 C  CB   . HIS A 1 138 ? 157.359 150.176 160.258 1.00 67.50  ? 149 HIS A CB   1 
ATOM   2118 C  CG   . HIS A 1 138 ? 158.160 149.477 159.207 1.00 70.35  ? 149 HIS A CG   1 
ATOM   2119 N  ND1  . HIS A 1 138 ? 158.794 148.274 159.430 1.00 76.05  ? 149 HIS A ND1  1 
ATOM   2120 C  CD2  . HIS A 1 138 ? 158.430 149.812 157.923 1.00 71.68  ? 149 HIS A CD2  1 
ATOM   2121 C  CE1  . HIS A 1 138 ? 159.422 147.899 158.330 1.00 76.18  ? 149 HIS A CE1  1 
ATOM   2122 N  NE2  . HIS A 1 138 ? 159.217 148.814 157.401 1.00 76.88  ? 149 HIS A NE2  1 
ATOM   2123 H  H    . HIS A 1 138 ? 159.891 151.801 160.822 1.00 74.19  ? 149 HIS A H    1 
ATOM   2124 H  HA   . HIS A 1 138 ? 158.008 152.081 159.897 1.00 72.46  ? 149 HIS A HA   1 
ATOM   2125 H  HB2  . HIS A 1 138 ? 157.302 149.590 161.027 1.00 72.25  ? 149 HIS A HB2  1 
ATOM   2126 H  HB3  . HIS A 1 138 ? 156.470 150.327 159.898 1.00 71.56  ? 149 HIS A HB3  1 
ATOM   2127 H  HD2  . HIS A 1 138 ? 158.138 150.575 157.479 1.00 71.97  ? 149 HIS A HD2  1 
ATOM   2128 H  HE1  . HIS A 1 138 ? 159.923 147.122 158.228 1.00 72.68  ? 149 HIS A HE1  1 
ATOM   2129 H  HE2  . HIS A 1 138 ? 159.525 148.790 156.598 1.00 72.63  ? 149 HIS A HE2  1 
ATOM   2130 N  N    . LEU A 1 139 ? 157.565 152.996 162.593 1.00 71.67  ? 150 LEU A N    1 
ATOM   2131 C  CA   . LEU A 1 139 ? 156.746 153.717 163.557 1.00 70.83  ? 150 LEU A CA   1 
ATOM   2132 C  C    . LEU A 1 139 ? 156.148 154.994 162.987 1.00 74.52  ? 150 LEU A C    1 
ATOM   2133 O  O    . LEU A 1 139 ? 155.166 155.499 163.540 1.00 74.35  ? 150 LEU A O    1 
ATOM   2134 C  CB   . LEU A 1 139 ? 157.567 154.062 164.800 1.00 71.96  ? 150 LEU A CB   1 
ATOM   2135 C  CG   . LEU A 1 139 ? 158.133 152.875 165.577 1.00 76.68  ? 150 LEU A CG   1 
ATOM   2136 C  CD1  . LEU A 1 139 ? 159.267 153.329 166.477 1.00 77.01  ? 150 LEU A CD1  1 
ATOM   2137 C  CD2  . LEU A 1 139 ? 157.043 152.191 166.390 1.00 74.53  ? 150 LEU A CD2  1 
ATOM   2138 H  H    . LEU A 1 139 ? 158.411 153.122 162.683 1.00 74.79  ? 150 LEU A H    1 
ATOM   2139 H  HA   . LEU A 1 139 ? 156.014 153.145 163.835 1.00 74.20  ? 150 LEU A HA   1 
ATOM   2140 H  HB2  . LEU A 1 139 ? 158.321 154.607 164.521 1.00 74.35  ? 150 LEU A HB2  1 
ATOM   2141 H  HB3  . LEU A 1 139 ? 157.009 154.570 165.407 1.00 74.52  ? 150 LEU A HB3  1 
ATOM   2142 H  HG   . LEU A 1 139 ? 158.487 152.226 164.950 1.00 75.33  ? 150 LEU A HG   1 
ATOM   2143 H  HD11 . LEU A 1 139 ? 159.497 152.606 167.081 1.00 76.18  ? 150 LEU A HD11 1 
ATOM   2144 H  HD12 . LEU A 1 139 ? 160.030 153.560 165.925 1.00 75.69  ? 150 LEU A HD12 1 
ATOM   2145 H  HD13 . LEU A 1 139 ? 158.975 154.101 166.983 1.00 75.70  ? 150 LEU A HD13 1 
ATOM   2146 H  HD21 . LEU A 1 139 ? 157.448 151.511 166.951 1.00 75.22  ? 150 LEU A HD21 1 
ATOM   2147 H  HD22 . LEU A 1 139 ? 156.599 152.854 166.941 1.00 74.88  ? 150 LEU A HD22 1 
ATOM   2148 H  HD23 . LEU A 1 139 ? 156.406 151.784 165.783 1.00 74.63  ? 150 LEU A HD23 1 
ATOM   2149 N  N    . LEU A 1 140 ? 156.707 155.528 161.903 1.00 60.02  ? 151 LEU A N    1 
ATOM   2150 C  CA   . LEU A 1 140 ? 156.187 156.768 161.343 1.00 56.62  ? 151 LEU A CA   1 
ATOM   2151 C  C    . LEU A 1 140 ? 154.896 156.497 160.587 1.00 43.59  ? 151 LEU A C    1 
ATOM   2152 O  O    . LEU A 1 140 ? 154.920 156.107 159.416 1.00 49.61  ? 151 LEU A O    1 
ATOM   2153 C  CB   . LEU A 1 140 ? 157.214 157.430 160.427 1.00 48.29  ? 151 LEU A CB   1 
ATOM   2154 C  CG   . LEU A 1 140 ? 156.792 158.807 159.916 1.00 44.83  ? 151 LEU A CG   1 
ATOM   2155 C  CD1  . LEU A 1 140 ? 157.041 159.865 160.979 1.00 53.85  ? 151 LEU A CD1  1 
ATOM   2156 C  CD2  . LEU A 1 140 ? 157.528 159.147 158.644 1.00 43.14  ? 151 LEU A CD2  1 
ATOM   2157 H  H    . LEU A 1 140 ? 157.378 155.197 161.479 1.00 55.57  ? 151 LEU A H    1 
ATOM   2158 H  HA   . LEU A 1 140 ? 155.987 157.382 162.067 1.00 56.14  ? 151 LEU A HA   1 
ATOM   2159 H  HB2  . LEU A 1 140 ? 158.048 157.530 160.910 1.00 54.71  ? 151 LEU A HB2  1 
ATOM   2160 H  HB3  . LEU A 1 140 ? 157.349 156.860 159.654 1.00 52.13  ? 151 LEU A HB3  1 
ATOM   2161 H  HG   . LEU A 1 140 ? 155.844 158.802 159.713 1.00 52.06  ? 151 LEU A HG   1 
ATOM   2162 H  HD11 . LEU A 1 140 ? 156.708 160.717 160.662 1.00 53.15  ? 151 LEU A HD11 1 
ATOM   2163 H  HD12 . LEU A 1 140 ? 156.574 159.610 161.790 1.00 54.07  ? 151 LEU A HD12 1 
ATOM   2164 H  HD13 . LEU A 1 140 ? 157.994 159.924 161.152 1.00 53.82  ? 151 LEU A HD13 1 
ATOM   2165 H  HD21 . LEU A 1 140 ? 158.483 159.072 158.800 1.00 52.09  ? 151 LEU A HD21 1 
ATOM   2166 H  HD22 . LEU A 1 140 ? 157.257 158.527 157.950 1.00 51.79  ? 151 LEU A HD22 1 
ATOM   2167 H  HD23 . LEU A 1 140 ? 157.302 160.054 158.384 1.00 52.17  ? 151 LEU A HD23 1 
ATOM   2168 N  N    . SER A 1 141 ? 153.764 156.691 161.260 1.00 48.44  ? 152 SER A N    1 
ATOM   2169 C  CA   . SER A 1 141 ? 152.477 156.466 160.616 1.00 50.50  ? 152 SER A CA   1 
ATOM   2170 C  C    . SER A 1 141 ? 152.244 157.459 159.487 1.00 50.12  ? 152 SER A C    1 
ATOM   2171 O  O    . SER A 1 141 ? 151.711 157.097 158.433 1.00 58.86  ? 152 SER A O    1 
ATOM   2172 C  CB   . SER A 1 141 ? 151.356 156.564 161.646 1.00 64.02  ? 152 SER A CB   1 
ATOM   2173 O  OG   . SER A 1 141 ? 151.309 157.860 162.219 1.00 66.46  ? 152 SER A OG   1 
ATOM   2174 H  H    . SER A 1 141 ? 153.715 156.949 162.079 1.00 59.48  ? 152 SER A H    1 
ATOM   2175 H  HA   . SER A 1 141 ? 152.462 155.573 160.239 1.00 57.38  ? 152 SER A HA   1 
ATOM   2176 H  HB2  . SER A 1 141 ? 150.513 156.379 161.203 1.00 59.95  ? 152 SER A HB2  1 
ATOM   2177 H  HB3  . SER A 1 141 ? 151.514 155.913 162.346 1.00 60.66  ? 152 SER A HB3  1 
ATOM   2178 H  HG   . SER A 1 141 ? 150.845 157.852 162.918 1.00 60.07  ? 152 SER A HG   1 
ATOM   2179 N  N    . TYR A 1 142 ? 152.627 158.718 159.690 1.00 45.25  ? 153 TYR A N    1 
ATOM   2180 C  CA   . TYR A 1 142 ? 152.376 159.750 158.697 1.00 47.06  ? 153 TYR A CA   1 
ATOM   2181 C  C    . TYR A 1 142 ? 153.470 160.803 158.760 1.00 43.62  ? 153 TYR A C    1 
ATOM   2182 O  O    . TYR A 1 142 ? 154.193 160.928 159.751 1.00 57.64  ? 153 TYR A O    1 
ATOM   2183 C  CB   . TYR A 1 142 ? 151.007 160.412 158.901 1.00 37.41  ? 153 TYR A CB   1 
ATOM   2184 C  CG   . TYR A 1 142 ? 149.838 159.476 158.705 1.00 45.12  ? 153 TYR A CG   1 
ATOM   2185 C  CD1  . TYR A 1 142 ? 149.514 158.997 157.445 1.00 53.50  ? 153 TYR A CD1  1 
ATOM   2186 C  CD2  . TYR A 1 142 ? 149.058 159.074 159.777 1.00 43.38  ? 153 TYR A CD2  1 
ATOM   2187 C  CE1  . TYR A 1 142 ? 148.449 158.141 157.259 1.00 54.62  ? 153 TYR A CE1  1 
ATOM   2188 C  CE2  . TYR A 1 142 ? 147.990 158.219 159.602 1.00 47.28  ? 153 TYR A CE2  1 
ATOM   2189 C  CZ   . TYR A 1 142 ? 147.690 157.756 158.341 1.00 54.78  ? 153 TYR A CZ   1 
ATOM   2190 O  OH   . TYR A 1 142 ? 146.624 156.903 158.161 1.00 62.34  ? 153 TYR A OH   1 
ATOM   2191 H  H    . TYR A 1 142 ? 153.036 158.996 160.394 1.00 51.94  ? 153 TYR A H    1 
ATOM   2192 H  HA   . TYR A 1 142 ? 152.392 159.353 157.811 1.00 52.12  ? 153 TYR A HA   1 
ATOM   2193 H  HB2  . TYR A 1 142 ? 150.960 160.760 159.805 1.00 49.25  ? 153 TYR A HB2  1 
ATOM   2194 H  HB3  . TYR A 1 142 ? 150.913 161.138 158.265 1.00 49.17  ? 153 TYR A HB3  1 
ATOM   2195 H  HD1  . TYR A 1 142 ? 150.026 159.255 156.713 1.00 50.92  ? 153 TYR A HD1  1 
ATOM   2196 H  HD2  . TYR A 1 142 ? 149.259 159.385 160.631 1.00 50.82  ? 153 TYR A HD2  1 
ATOM   2197 H  HE1  . TYR A 1 142 ? 148.244 157.828 156.407 1.00 51.01  ? 153 TYR A HE1  1 
ATOM   2198 H  HE2  . TYR A 1 142 ? 147.475 157.957 160.331 1.00 51.43  ? 153 TYR A HE2  1 
ATOM   2199 H  HH   . TYR A 1 142 ? 146.561 156.690 157.351 1.00 52.18  ? 153 TYR A HH   1 
ATOM   2200 N  N    . LEU A 1 143 ? 153.590 161.548 157.668 1.00 37.89  ? 154 LEU A N    1 
ATOM   2201 C  CA   . LEU A 1 143 ? 154.396 162.755 157.601 1.00 33.66  ? 154 LEU A CA   1 
ATOM   2202 C  C    . LEU A 1 143 ? 153.472 163.907 157.249 1.00 44.23  ? 154 LEU A C    1 
ATOM   2203 O  O    . LEU A 1 143 ? 152.508 163.725 156.503 1.00 52.28  ? 154 LEU A O    1 
ATOM   2204 C  CB   . LEU A 1 143 ? 155.514 162.626 156.561 1.00 35.60  ? 154 LEU A CB   1 
ATOM   2205 C  CG   . LEU A 1 143 ? 156.206 163.916 156.110 1.00 41.64  ? 154 LEU A CG   1 
ATOM   2206 C  CD1  . LEU A 1 143 ? 157.073 164.469 157.221 1.00 39.56  ? 154 LEU A CD1  1 
ATOM   2207 C  CD2  . LEU A 1 143 ? 157.038 163.675 154.861 1.00 56.56  ? 154 LEU A CD2  1 
ATOM   2208 H  H    . LEU A 1 143 ? 153.195 161.365 156.925 1.00 47.38  ? 154 LEU A H    1 
ATOM   2209 H  HA   . LEU A 1 143 ? 154.796 162.932 158.467 1.00 46.76  ? 154 LEU A HA   1 
ATOM   2210 H  HB2  . LEU A 1 143 ? 156.201 162.049 156.929 1.00 45.62  ? 154 LEU A HB2  1 
ATOM   2211 H  HB3  . LEU A 1 143 ? 155.139 162.210 155.770 1.00 45.91  ? 154 LEU A HB3  1 
ATOM   2212 H  HG   . LEU A 1 143 ? 155.541 164.586 155.889 1.00 45.26  ? 154 LEU A HG   1 
ATOM   2213 H  HD11 . LEU A 1 143 ? 157.431 165.328 156.946 1.00 45.47  ? 154 LEU A HD11 1 
ATOM   2214 H  HD12 . LEU A 1 143 ? 156.531 164.576 158.018 1.00 46.99  ? 154 LEU A HD12 1 
ATOM   2215 H  HD13 . LEU A 1 143 ? 157.798 163.848 157.395 1.00 45.21  ? 154 LEU A HD13 1 
ATOM   2216 H  HD21 . LEU A 1 143 ? 157.169 164.521 154.405 1.00 47.68  ? 154 LEU A HD21 1 
ATOM   2217 H  HD22 . LEU A 1 143 ? 157.895 163.302 155.118 1.00 48.04  ? 154 LEU A HD22 1 
ATOM   2218 H  HD23 . LEU A 1 143 ? 156.567 163.059 154.279 1.00 47.84  ? 154 LEU A HD23 1 
ATOM   2219 N  N    . VAL A 1 144 ? 153.742 165.084 157.802 1.00 57.78  ? 155 VAL A N    1 
ATOM   2220 C  CA   . VAL A 1 144 ? 152.935 166.266 157.531 1.00 54.67  ? 155 VAL A CA   1 
ATOM   2221 C  C    . VAL A 1 144 ? 153.867 167.428 157.231 1.00 53.43  ? 155 VAL A C    1 
ATOM   2222 O  O    . VAL A 1 144 ? 154.846 167.646 157.952 1.00 64.16  ? 155 VAL A O    1 
ATOM   2223 C  CB   . VAL A 1 144 ? 152.005 166.614 158.706 1.00 61.82  ? 155 VAL A CB   1 
ATOM   2224 C  CG1  . VAL A 1 144 ? 151.262 167.912 158.417 1.00 58.40  ? 155 VAL A CG1  1 
ATOM   2225 C  CG2  . VAL A 1 144 ? 151.031 165.476 158.967 1.00 60.91  ? 155 VAL A CG2  1 
ATOM   2226 H  H    . VAL A 1 144 ? 154.394 165.224 158.344 1.00 57.61  ? 155 VAL A H    1 
ATOM   2227 H  HA   . VAL A 1 144 ? 152.387 166.108 156.747 1.00 56.84  ? 155 VAL A HA   1 
ATOM   2228 H  HB   . VAL A 1 144 ? 152.537 166.742 159.505 1.00 58.72  ? 155 VAL A HB   1 
ATOM   2229 H  HG11 . VAL A 1 144 ? 150.595 168.050 159.102 1.00 58.32  ? 155 VAL A HG11 1 
ATOM   2230 H  HG12 . VAL A 1 144 ? 151.890 168.652 158.423 1.00 57.71  ? 155 VAL A HG12 1 
ATOM   2231 H  HG13 . VAL A 1 144 ? 150.834 167.845 157.549 1.00 58.34  ? 155 VAL A HG13 1 
ATOM   2232 H  HG21 . VAL A 1 144 ? 150.535 165.666 159.778 1.00 58.72  ? 155 VAL A HG21 1 
ATOM   2233 H  HG22 . VAL A 1 144 ? 150.423 165.402 158.214 1.00 57.80  ? 155 VAL A HG22 1 
ATOM   2234 H  HG23 . VAL A 1 144 ? 151.530 164.650 159.073 1.00 57.92  ? 155 VAL A HG23 1 
ATOM   2235 N  N    . VAL A 1 145 ? 153.556 168.172 156.176 1.00 45.57  ? 156 VAL A N    1 
ATOM   2236 C  CA   . VAL A 1 145 ? 154.317 169.349 155.776 1.00 49.17  ? 156 VAL A CA   1 
ATOM   2237 C  C    . VAL A 1 145 ? 153.349 170.524 155.802 1.00 57.63  ? 156 VAL A C    1 
ATOM   2238 O  O    . VAL A 1 145 ? 152.603 170.748 154.840 1.00 65.41  ? 156 VAL A O    1 
ATOM   2239 C  CB   . VAL A 1 145 ? 154.962 169.186 154.396 1.00 50.23  ? 156 VAL A CB   1 
ATOM   2240 C  CG1  . VAL A 1 145 ? 155.817 170.396 154.065 1.00 55.21  ? 156 VAL A CG1  1 
ATOM   2241 C  CG2  . VAL A 1 145 ? 155.790 167.911 154.340 1.00 55.61  ? 156 VAL A CG2  1 
ATOM   2242 H  H    . VAL A 1 145 ? 152.888 168.008 155.660 1.00 54.41  ? 156 VAL A H    1 
ATOM   2243 H  HA   . VAL A 1 145 ? 155.016 169.520 156.424 1.00 54.86  ? 156 VAL A HA   1 
ATOM   2244 H  HB   . VAL A 1 145 ? 154.263 169.120 153.726 1.00 54.28  ? 156 VAL A HB   1 
ATOM   2245 H  HG11 . VAL A 1 145 ? 156.374 170.188 153.299 1.00 54.97  ? 156 VAL A HG11 1 
ATOM   2246 H  HG12 . VAL A 1 145 ? 155.237 171.146 153.859 1.00 55.32  ? 156 VAL A HG12 1 
ATOM   2247 H  HG13 . VAL A 1 145 ? 156.374 170.606 154.831 1.00 55.21  ? 156 VAL A HG13 1 
ATOM   2248 H  HG21 . VAL A 1 145 ? 156.280 167.888 153.502 1.00 55.34  ? 156 VAL A HG21 1 
ATOM   2249 H  HG22 . VAL A 1 145 ? 156.410 167.904 155.086 1.00 55.07  ? 156 VAL A HG22 1 
ATOM   2250 H  HG23 . VAL A 1 145 ? 155.197 167.145 154.396 1.00 55.41  ? 156 VAL A HG23 1 
ATOM   2251 N  N    . ASP A 1 146 ? 153.345 171.267 156.905 1.00 67.79  ? 157 ASP A N    1 
ATOM   2252 C  CA   . ASP A 1 146 ? 152.550 172.482 156.990 1.00 68.43  ? 157 ASP A CA   1 
ATOM   2253 C  C    . ASP A 1 146 ? 153.201 173.590 156.173 1.00 67.69  ? 157 ASP A C    1 
ATOM   2254 O  O    . ASP A 1 146 ? 154.410 173.590 155.939 1.00 72.14  ? 157 ASP A O    1 
ATOM   2255 C  CB   . ASP A 1 146 ? 152.404 172.928 158.444 1.00 68.93  ? 157 ASP A CB   1 
ATOM   2256 C  CG   . ASP A 1 146 ? 151.543 171.986 159.260 1.00 68.80  ? 157 ASP A CG   1 
ATOM   2257 O  OD1  . ASP A 1 146 ? 150.642 171.349 158.678 1.00 66.59  ? 157 ASP A OD1  1 
ATOM   2258 O  OD2  . ASP A 1 146 ? 151.768 171.884 160.484 1.00 71.58  ? 157 ASP A OD2  1 
ATOM   2259 H  H    . ASP A 1 146 ? 153.794 171.087 157.616 1.00 67.20  ? 157 ASP A H    1 
ATOM   2260 H  HA   . ASP A 1 146 ? 151.666 172.316 156.630 1.00 67.64  ? 157 ASP A HA   1 
ATOM   2261 H  HB2  . ASP A 1 146 ? 153.283 172.962 158.854 1.00 68.38  ? 157 ASP A HB2  1 
ATOM   2262 H  HB3  . ASP A 1 146 ? 151.993 173.806 158.466 1.00 67.76  ? 157 ASP A HB3  1 
ATOM   2263 N  N    . GLU A 1 147 ? 152.383 174.548 155.739 1.00 71.09  ? 158 GLU A N    1 
ATOM   2264 C  CA   . GLU A 1 147 ? 152.860 175.651 154.908 1.00 72.02  ? 158 GLU A CA   1 
ATOM   2265 C  C    . GLU A 1 147 ? 153.544 175.113 153.654 1.00 78.72  ? 158 GLU A C    1 
ATOM   2266 O  O    . GLU A 1 147 ? 154.639 175.538 153.280 1.00 81.33  ? 158 GLU A O    1 
ATOM   2267 C  CB   . GLU A 1 147 ? 153.802 176.562 155.697 1.00 74.18  ? 158 GLU A CB   1 
ATOM   2268 C  CG   . GLU A 1 147 ? 153.325 176.883 157.101 1.00 79.59  ? 158 GLU A CG   1 
ATOM   2269 C  CD   . GLU A 1 147 ? 151.864 177.278 157.141 1.00 82.43  ? 158 GLU A CD   1 
ATOM   2270 O  OE1  . GLU A 1 147 ? 151.503 178.282 156.492 1.00 85.77  ? 158 GLU A OE1  1 
ATOM   2271 O  OE2  . GLU A 1 147 ? 151.076 176.585 157.818 1.00 81.26  ? 158 GLU A OE2  1 
ATOM   2272 H  H    . GLU A 1 147 ? 151.542 174.581 155.914 1.00 76.46  ? 158 GLU A H    1 
ATOM   2273 H  HA   . GLU A 1 147 ? 152.100 176.182 154.625 1.00 76.41  ? 158 GLU A HA   1 
ATOM   2274 H  HB2  . GLU A 1 147 ? 154.668 176.130 155.770 1.00 77.12  ? 158 GLU A HB2  1 
ATOM   2275 H  HB3  . GLU A 1 147 ? 153.894 177.401 155.220 1.00 76.77  ? 158 GLU A HB3  1 
ATOM   2276 H  HG2  . GLU A 1 147 ? 153.440 176.100 157.662 1.00 77.16  ? 158 GLU A HG2  1 
ATOM   2277 H  HG3  . GLU A 1 147 ? 153.846 177.622 157.452 1.00 77.20  ? 158 GLU A HG3  1 
ATOM   2278 N  N    . ALA A 1 148 ? 152.879 174.160 152.999 1.00 68.15  ? 159 ALA A N    1 
ATOM   2279 C  CA   . ALA A 1 148 ? 153.471 173.511 151.836 1.00 63.50  ? 159 ALA A CA   1 
ATOM   2280 C  C    . ALA A 1 148 ? 153.814 174.514 150.744 1.00 62.11  ? 159 ALA A C    1 
ATOM   2281 O  O    . ALA A 1 148 ? 154.729 174.273 149.949 1.00 63.22  ? 159 ALA A O    1 
ATOM   2282 C  CB   . ALA A 1 148 ? 152.523 172.443 151.294 1.00 62.87  ? 159 ALA A CB   1 
ATOM   2283 H  H    . ALA A 1 148 ? 152.095 173.876 153.206 1.00 64.83  ? 159 ALA A H    1 
ATOM   2284 H  HA   . ALA A 1 148 ? 154.293 173.072 152.105 1.00 63.59  ? 159 ALA A HA   1 
ATOM   2285 H  HB1  . ALA A 1 148 ? 152.935 172.019 150.526 1.00 63.21  ? 159 ALA A HB1  1 
ATOM   2286 H  HB2  . ALA A 1 148 ? 152.360 171.785 151.987 1.00 63.02  ? 159 ALA A HB2  1 
ATOM   2287 H  HB3  . ALA A 1 148 ? 151.688 172.863 151.033 1.00 63.43  ? 159 ALA A HB3  1 
ATOM   2288 N  N    . HIS A 1 149 ? 153.104 175.643 150.689 1.00 67.41  ? 160 HIS A N    1 
ATOM   2289 C  CA   . HIS A 1 149 ? 153.373 176.634 149.655 1.00 73.85  ? 160 HIS A CA   1 
ATOM   2290 C  C    . HIS A 1 149 ? 154.790 177.185 149.739 1.00 73.23  ? 160 HIS A C    1 
ATOM   2291 O  O    . HIS A 1 149 ? 155.286 177.740 148.753 1.00 73.65  ? 160 HIS A O    1 
ATOM   2292 C  CB   . HIS A 1 149 ? 152.363 177.778 149.745 1.00 75.36  ? 160 HIS A CB   1 
ATOM   2293 C  CG   . HIS A 1 149 ? 152.510 178.621 150.973 1.00 72.93  ? 160 HIS A CG   1 
ATOM   2294 N  ND1  . HIS A 1 149 ? 152.418 178.104 152.247 1.00 69.86  ? 160 HIS A ND1  1 
ATOM   2295 C  CD2  . HIS A 1 149 ? 152.742 179.947 151.121 1.00 72.32  ? 160 HIS A CD2  1 
ATOM   2296 C  CE1  . HIS A 1 149 ? 152.586 179.075 153.127 1.00 73.09  ? 160 HIS A CE1  1 
ATOM   2297 N  NE2  . HIS A 1 149 ? 152.785 180.203 152.470 1.00 73.27  ? 160 HIS A NE2  1 
ATOM   2298 H  H    . HIS A 1 149 ? 152.471 175.854 151.232 1.00 71.18  ? 160 HIS A H    1 
ATOM   2299 H  HA   . HIS A 1 149 ? 153.270 176.214 148.786 1.00 72.44  ? 160 HIS A HA   1 
ATOM   2300 H  HB2  . HIS A 1 149 ? 152.479 178.357 148.975 1.00 72.57  ? 160 HIS A HB2  1 
ATOM   2301 H  HB3  . HIS A 1 149 ? 151.468 177.407 149.743 1.00 71.95  ? 160 HIS A HB3  1 
ATOM   2302 H  HD2  . HIS A 1 149 ? 152.852 180.568 150.438 1.00 71.57  ? 160 HIS A HD2  1 
ATOM   2303 H  HE1  . HIS A 1 149 ? 152.569 178.980 154.052 1.00 72.59  ? 160 HIS A HE1  1 
ATOM   2304 H  HE2  . HIS A 1 149 ? 152.919 180.973 152.829 1.00 72.21  ? 160 HIS A HE2  1 
ATOM   2305 N  N    . CYS A 1 150 ? 155.451 177.047 150.890 1.00 70.87  ? 161 CYS A N    1 
ATOM   2306 C  CA   . CYS A 1 150 ? 156.819 177.538 151.017 1.00 76.32  ? 161 CYS A CA   1 
ATOM   2307 C  C    . CYS A 1 150 ? 157.760 176.837 150.046 1.00 79.91  ? 161 CYS A C    1 
ATOM   2308 O  O    . CYS A 1 150 ? 158.780 177.411 149.648 1.00 79.00  ? 161 CYS A O    1 
ATOM   2309 C  CB   . CYS A 1 150 ? 157.307 177.359 152.453 1.00 73.03  ? 161 CYS A CB   1 
ATOM   2310 S  SG   . CYS A 1 150 ? 156.428 178.373 153.661 1.00 80.82  ? 161 CYS A SG   1 
ATOM   2311 H  H    . CYS A 1 150 ? 155.136 176.679 151.601 1.00 74.10  ? 161 CYS A H    1 
ATOM   2312 H  HA   . CYS A 1 150 ? 156.834 178.484 150.814 1.00 76.01  ? 161 CYS A HA   1 
ATOM   2313 H  HB2  . CYS A 1 150 ? 157.198 176.430 152.708 1.00 75.31  ? 161 CYS A HB2  1 
ATOM   2314 H  HB3  . CYS A 1 150 ? 158.244 177.604 152.492 1.00 75.96  ? 161 CYS A HB3  1 
ATOM   2315 H  HG   . CYS A 1 150 ? 155.258 178.119 153.586 1.00 76.09  ? 161 CYS A HG   1 
ATOM   2316 N  N    . VAL A 1 151 ? 157.444 175.601 149.658 1.00 69.68  ? 162 VAL A N    1 
ATOM   2317 C  CA   . VAL A 1 151 ? 158.301 174.881 148.721 1.00 66.61  ? 162 VAL A CA   1 
ATOM   2318 C  C    . VAL A 1 151 ? 158.319 175.575 147.366 1.00 70.57  ? 162 VAL A C    1 
ATOM   2319 O  O    . VAL A 1 151 ? 159.356 175.628 146.694 1.00 72.76  ? 162 VAL A O    1 
ATOM   2320 C  CB   . VAL A 1 151 ? 157.850 173.414 148.601 1.00 66.51  ? 162 VAL A CB   1 
ATOM   2321 C  CG1  . VAL A 1 151 ? 156.580 173.309 147.783 1.00 65.36  ? 162 VAL A CG1  1 
ATOM   2322 C  CG2  . VAL A 1 151 ? 158.950 172.589 147.964 1.00 69.45  ? 162 VAL A CG2  1 
ATOM   2323 H  H    . VAL A 1 151 ? 156.751 175.164 149.919 1.00 68.21  ? 162 VAL A H    1 
ATOM   2324 H  HA   . VAL A 1 151 ? 159.208 174.885 149.065 1.00 67.79  ? 162 VAL A HA   1 
ATOM   2325 H  HB   . VAL A 1 151 ? 157.674 173.056 149.485 1.00 67.40  ? 162 VAL A HB   1 
ATOM   2326 H  HG11 . VAL A 1 151 ? 156.113 172.499 148.040 1.00 66.97  ? 162 VAL A HG11 1 
ATOM   2327 H  HG12 . VAL A 1 151 ? 156.022 174.081 147.963 1.00 67.51  ? 162 VAL A HG12 1 
ATOM   2328 H  HG13 . VAL A 1 151 ? 156.807 173.280 146.841 1.00 68.10  ? 162 VAL A HG13 1 
ATOM   2329 H  HG21 . VAL A 1 151 ? 158.750 171.647 148.077 1.00 68.18  ? 162 VAL A HG21 1 
ATOM   2330 H  HG22 . VAL A 1 151 ? 158.999 172.808 147.021 1.00 68.10  ? 162 VAL A HG22 1 
ATOM   2331 H  HG23 . VAL A 1 151 ? 159.791 172.804 148.392 1.00 68.05  ? 162 VAL A HG23 1 
ATOM   2332 N  N    . SER A 1 152 ? 157.181 176.116 146.944 1.00 68.63  ? 163 SER A N    1 
ATOM   2333 C  CA   . SER A 1 152 ? 157.082 176.740 145.632 1.00 66.97  ? 163 SER A CA   1 
ATOM   2334 C  C    . SER A 1 152 ? 157.618 178.163 145.681 1.00 66.90  ? 163 SER A C    1 
ATOM   2335 O  O    . SER A 1 152 ? 157.237 178.949 146.554 1.00 71.87  ? 163 SER A O    1 
ATOM   2336 C  CB   . SER A 1 152 ? 155.633 176.749 145.154 1.00 65.61  ? 163 SER A CB   1 
ATOM   2337 O  OG   . SER A 1 152 ? 154.900 177.781 145.788 1.00 65.15  ? 163 SER A OG   1 
ATOM   2338 H  H    . SER A 1 152 ? 156.452 176.135 147.398 1.00 68.18  ? 163 SER A H    1 
ATOM   2339 H  HA   . SER A 1 152 ? 157.612 176.236 144.995 1.00 67.65  ? 163 SER A HA   1 
ATOM   2340 H  HB2  . SER A 1 152 ? 155.619 176.897 144.195 1.00 67.55  ? 163 SER A HB2  1 
ATOM   2341 H  HB3  . SER A 1 152 ? 155.225 175.894 145.365 1.00 68.15  ? 163 SER A HB3  1 
ATOM   2342 H  HG   . SER A 1 152 ? 154.148 177.860 145.426 1.00 67.69  ? 163 SER A HG   1 
ATOM   2343 N  N    . GLN A 1 153 ? 158.504 178.493 144.741 1.00 72.43  ? 164 GLN A N    1 
ATOM   2344 C  CA   . GLN A 1 153 ? 158.961 179.872 144.622 1.00 79.72  ? 164 GLN A CA   1 
ATOM   2345 C  C    . GLN A 1 153 ? 157.818 180.790 144.211 1.00 79.13  ? 164 GLN A C    1 
ATOM   2346 O  O    . GLN A 1 153 ? 157.712 181.919 144.704 1.00 79.44  ? 164 GLN A O    1 
ATOM   2347 C  CB   . GLN A 1 153 ? 160.114 179.959 143.621 1.00 81.29  ? 164 GLN A CB   1 
ATOM   2348 C  CG   . GLN A 1 153 ? 161.379 179.253 144.085 1.00 80.92  ? 164 GLN A CG   1 
ATOM   2349 C  CD   . GLN A 1 153 ? 162.504 179.334 143.073 1.00 83.03  ? 164 GLN A CD   1 
ATOM   2350 O  OE1  . GLN A 1 153 ? 162.333 179.864 141.977 1.00 85.23  ? 164 GLN A OE1  1 
ATOM   2351 N  NE2  . GLN A 1 153 ? 163.667 178.811 143.441 1.00 82.30  ? 164 GLN A NE2  1 
ATOM   2352 H  H    . GLN A 1 153 ? 158.848 177.947 144.172 1.00 78.34  ? 164 GLN A H    1 
ATOM   2353 H  HA   . GLN A 1 153 ? 159.290 180.170 145.484 1.00 80.31  ? 164 GLN A HA   1 
ATOM   2354 H  HB2  . GLN A 1 153 ? 159.836 179.552 142.786 1.00 80.04  ? 164 GLN A HB2  1 
ATOM   2355 H  HB3  . GLN A 1 153 ? 160.331 180.893 143.476 1.00 79.89  ? 164 GLN A HB3  1 
ATOM   2356 H  HG2  . GLN A 1 153 ? 161.686 179.666 144.908 1.00 79.95  ? 164 GLN A HG2  1 
ATOM   2357 H  HG3  . GLN A 1 153 ? 161.180 178.316 144.238 1.00 79.87  ? 164 GLN A HG3  1 
ATOM   2358 H  HE21 . GLN A 1 153 ? 163.750 178.449 144.217 1.00 79.95  ? 164 GLN A HE21 1 
ATOM   2359 H  HE22 . GLN A 1 153 ? 164.338 178.832 142.903 1.00 80.41  ? 164 GLN A HE22 1 
ATOM   2360 N  N    . TRP A 1 154 ? 156.946 180.318 143.318 1.00 87.17  ? 165 TRP A N    1 
ATOM   2361 C  CA   . TRP A 1 154 ? 155.825 181.138 142.870 1.00 88.16  ? 165 TRP A CA   1 
ATOM   2362 C  C    . TRP A 1 154 ? 154.908 181.513 144.026 1.00 85.26  ? 165 TRP A C    1 
ATOM   2363 O  O    . TRP A 1 154 ? 154.179 182.508 143.942 1.00 87.57  ? 165 TRP A O    1 
ATOM   2364 C  CB   . TRP A 1 154 ? 155.046 180.398 141.781 1.00 85.82  ? 165 TRP A CB   1 
ATOM   2365 C  CG   . TRP A 1 154 ? 155.816 180.260 140.503 1.00 80.64  ? 165 TRP A CG   1 
ATOM   2366 C  CD1  . TRP A 1 154 ? 156.651 179.237 140.157 1.00 80.46  ? 165 TRP A CD1  1 
ATOM   2367 C  CD2  . TRP A 1 154 ? 155.829 181.177 139.402 1.00 85.74  ? 165 TRP A CD2  1 
ATOM   2368 N  NE1  . TRP A 1 154 ? 157.182 179.460 138.910 1.00 83.30  ? 165 TRP A NE1  1 
ATOM   2369 C  CE2  . TRP A 1 154 ? 156.693 180.644 138.425 1.00 89.78  ? 165 TRP A CE2  1 
ATOM   2370 C  CE3  . TRP A 1 154 ? 155.193 182.395 139.148 1.00 88.15  ? 165 TRP A CE3  1 
ATOM   2371 C  CZ2  . TRP A 1 154 ? 156.936 181.288 137.214 1.00 90.35  ? 165 TRP A CZ2  1 
ATOM   2372 C  CZ3  . TRP A 1 154 ? 155.437 183.033 137.945 1.00 89.29  ? 165 TRP A CZ3  1 
ATOM   2373 C  CH2  . TRP A 1 154 ? 156.300 182.479 136.993 1.00 88.10  ? 165 TRP A CH2  1 
ATOM   2374 H  H    . TRP A 1 154 ? 156.981 179.535 142.962 1.00 85.67  ? 165 TRP A H    1 
ATOM   2375 H  HA   . TRP A 1 154 ? 156.171 181.958 142.485 1.00 86.25  ? 165 TRP A HA   1 
ATOM   2376 H  HB2  . TRP A 1 154 ? 154.830 179.507 142.098 1.00 85.94  ? 165 TRP A HB2  1 
ATOM   2377 H  HB3  . TRP A 1 154 ? 154.230 180.888 141.589 1.00 85.93  ? 165 TRP A HB3  1 
ATOM   2378 H  HD1  . TRP A 1 154 ? 156.835 178.497 140.689 1.00 85.50  ? 165 TRP A HD1  1 
ATOM   2379 H  HE1  . TRP A 1 154 ? 157.731 178.941 138.500 1.00 85.49  ? 165 TRP A HE1  1 
ATOM   2380 H  HE3  . TRP A 1 154 ? 154.618 182.770 139.776 1.00 86.09  ? 165 TRP A HE3  1 
ATOM   2381 H  HZ2  . TRP A 1 154 ? 157.509 180.922 136.579 1.00 86.36  ? 165 TRP A HZ2  1 
ATOM   2382 H  HZ3  . TRP A 1 154 ? 155.019 183.845 137.766 1.00 86.19  ? 165 TRP A HZ3  1 
ATOM   2383 H  HH2  . TRP A 1 154 ? 156.445 182.930 136.193 1.00 85.96  ? 165 TRP A HH2  1 
ATOM   2384 N  N    . GLY A 1 155 ? 154.926 180.736 145.107 1.00 83.13  ? 166 GLY A N    1 
ATOM   2385 C  CA   . GLY A 1 155 ? 154.140 181.092 146.273 1.00 88.01  ? 166 GLY A CA   1 
ATOM   2386 C  C    . GLY A 1 155 ? 154.605 182.400 146.885 1.00 86.43  ? 166 GLY A C    1 
ATOM   2387 O  O    . GLY A 1 155 ? 155.743 182.835 146.693 1.00 85.92  ? 166 GLY A O    1 
ATOM   2388 H  H    . GLY A 1 155 ? 155.377 180.008 145.186 1.00 83.22  ? 166 GLY A H    1 
ATOM   2389 H  HA2  . GLY A 1 155 ? 153.207 181.181 146.024 1.00 84.81  ? 166 GLY A HA2  1 
ATOM   2390 H  HA3  . GLY A 1 155 ? 154.217 180.394 146.942 1.00 83.88  ? 166 GLY A HA3  1 
ATOM   2391 N  N    . HIS A 1 156 ? 153.702 183.038 147.632 1.00 83.27  ? 167 HIS A N    1 
ATOM   2392 C  CA   . HIS A 1 156 ? 154.018 184.330 148.233 1.00 85.15  ? 167 HIS A CA   1 
ATOM   2393 C  C    . HIS A 1 156 ? 155.212 184.222 149.174 1.00 91.86  ? 167 HIS A C    1 
ATOM   2394 O  O    . HIS A 1 156 ? 156.120 185.061 149.143 1.00 92.33  ? 167 HIS A O    1 
ATOM   2395 C  CB   . HIS A 1 156 ? 152.795 184.872 148.974 1.00 84.99  ? 167 HIS A CB   1 
ATOM   2396 H  H    . HIS A 1 156 ? 152.910 182.747 147.802 1.00 86.69  ? 167 HIS A H    1 
ATOM   2397 H  HA   . HIS A 1 156 ? 154.245 184.958 147.529 1.00 86.92  ? 167 HIS A HA   1 
ATOM   2398 N  N    . ASP A 1 157 ? 155.228 183.195 150.019 1.00 93.62  ? 168 ASP A N    1 
ATOM   2399 C  CA   . ASP A 1 157 ? 156.328 182.935 150.939 1.00 90.23  ? 168 ASP A CA   1 
ATOM   2400 C  C    . ASP A 1 157 ? 157.008 181.635 150.537 1.00 84.33  ? 168 ASP A C    1 
ATOM   2401 O  O    . ASP A 1 157 ? 156.331 180.643 150.249 1.00 83.88  ? 168 ASP A O    1 
ATOM   2402 C  CB   . ASP A 1 157 ? 155.828 182.852 152.383 1.00 90.44  ? 168 ASP A CB   1 
ATOM   2403 C  CG   . ASP A 1 157 ? 155.180 184.140 152.851 1.00 88.14  ? 168 ASP A CG   1 
ATOM   2404 O  OD1  . ASP A 1 157 ? 155.126 185.103 152.057 1.00 86.80  ? 168 ASP A OD1  1 
ATOM   2405 O  OD2  . ASP A 1 157 ? 154.724 184.190 154.013 1.00 86.47  ? 168 ASP A OD2  1 
ATOM   2406 H  H    . ASP A 1 157 ? 154.592 182.620 150.078 1.00 87.92  ? 168 ASP A H    1 
ATOM   2407 H  HA   . ASP A 1 157 ? 156.978 183.652 150.882 1.00 88.06  ? 168 ASP A HA   1 
ATOM   2408 H  HB2  . ASP A 1 157 ? 155.168 182.144 152.449 1.00 87.97  ? 168 ASP A HB2  1 
ATOM   2409 H  HB3  . ASP A 1 157 ? 156.579 182.663 152.967 1.00 88.09  ? 168 ASP A HB3  1 
ATOM   2410 N  N    . PHE A 1 158 ? 158.341 181.643 150.511 1.00 77.41  ? 169 PHE A N    1 
ATOM   2411 C  CA   . PHE A 1 158 ? 159.122 180.513 150.027 1.00 77.90  ? 169 PHE A CA   1 
ATOM   2412 C  C    . PHE A 1 158 ? 160.193 180.140 151.042 1.00 80.15  ? 169 PHE A C    1 
ATOM   2413 O  O    . PHE A 1 158 ? 160.760 181.010 151.709 1.00 85.98  ? 169 PHE A O    1 
ATOM   2414 C  CB   . PHE A 1 158 ? 159.764 180.840 148.669 1.00 77.18  ? 169 PHE A CB   1 
ATOM   2415 C  CG   . PHE A 1 158 ? 160.942 179.973 148.325 1.00 78.63  ? 169 PHE A CG   1 
ATOM   2416 C  CD1  . PHE A 1 158 ? 162.225 180.340 148.694 1.00 76.11  ? 169 PHE A CD1  1 
ATOM   2417 C  CD2  . PHE A 1 158 ? 160.762 178.786 147.635 1.00 84.44  ? 169 PHE A CD2  1 
ATOM   2418 C  CE1  . PHE A 1 158 ? 163.306 179.542 148.377 1.00 80.13  ? 169 PHE A CE1  1 
ATOM   2419 C  CE2  . PHE A 1 158 ? 161.839 177.984 147.317 1.00 84.91  ? 169 PHE A CE2  1 
ATOM   2420 C  CZ   . PHE A 1 158 ? 163.113 178.362 147.689 1.00 80.16  ? 169 PHE A CZ   1 
ATOM   2421 H  H    . PHE A 1 158 ? 158.821 182.307 150.773 1.00 80.29  ? 169 PHE A H    1 
ATOM   2422 H  HA   . PHE A 1 158 ? 158.537 179.750 149.909 1.00 79.51  ? 169 PHE A HA   1 
ATOM   2423 H  HB2  . PHE A 1 158 ? 159.098 180.723 147.973 1.00 79.77  ? 169 PHE A HB2  1 
ATOM   2424 H  HB3  . PHE A 1 158 ? 160.069 181.761 148.681 1.00 79.37  ? 169 PHE A HB3  1 
ATOM   2425 H  HD1  . PHE A 1 158 ? 162.360 181.134 149.158 1.00 79.32  ? 169 PHE A HD1  1 
ATOM   2426 H  HD2  . PHE A 1 158 ? 159.906 178.527 147.382 1.00 79.82  ? 169 PHE A HD2  1 
ATOM   2427 H  HE1  . PHE A 1 158 ? 164.163 179.798 148.630 1.00 80.28  ? 169 PHE A HE1  1 
ATOM   2428 H  HE2  . PHE A 1 158 ? 161.707 177.190 146.853 1.00 80.27  ? 169 PHE A HE2  1 
ATOM   2429 H  HZ   . PHE A 1 158 ? 163.840 177.823 147.476 1.00 79.47  ? 169 PHE A HZ   1 
ATOM   2430 N  N    . ARG A 1 159 ? 160.463 178.839 151.153 1.00 73.25  ? 170 ARG A N    1 
ATOM   2431 C  CA   . ARG A 1 159 ? 161.490 178.314 152.049 1.00 72.54  ? 170 ARG A CA   1 
ATOM   2432 C  C    . ARG A 1 159 ? 162.317 177.287 151.284 1.00 76.25  ? 170 ARG A C    1 
ATOM   2433 O  O    . ARG A 1 159 ? 161.759 176.270 150.822 1.00 76.99  ? 170 ARG A O    1 
ATOM   2434 C  CB   . ARG A 1 159 ? 160.858 177.682 153.292 1.00 74.11  ? 170 ARG A CB   1 
ATOM   2435 C  CG   . ARG A 1 159 ? 161.853 177.084 154.276 1.00 71.95  ? 170 ARG A CG   1 
ATOM   2436 C  CD   . ARG A 1 159 ? 162.688 178.144 154.975 1.00 76.89  ? 170 ARG A CD   1 
ATOM   2437 N  NE   . ARG A 1 159 ? 161.904 178.908 155.939 1.00 78.97  ? 170 ARG A NE   1 
ATOM   2438 C  CZ   . ARG A 1 159 ? 161.643 178.508 157.177 1.00 80.56  ? 170 ARG A CZ   1 
ATOM   2439 N  NH1  . ARG A 1 159 ? 162.073 177.343 157.633 1.00 79.11  ? 170 ARG A NH1  1 
ATOM   2440 N  NH2  . ARG A 1 159 ? 160.932 179.297 157.977 1.00 81.80  ? 170 ARG A NH2  1 
ATOM   2441 H  H    . ARG A 1 159 ? 160.051 178.228 150.709 1.00 75.80  ? 170 ARG A H    1 
ATOM   2442 H  HA   . ARG A 1 159 ? 162.058 179.042 152.336 1.00 75.53  ? 170 ARG A HA   1 
ATOM   2443 H  HB2  . ARG A 1 159 ? 160.347 178.359 153.763 1.00 75.98  ? 170 ARG A HB2  1 
ATOM   2444 H  HB3  . ARG A 1 159 ? 160.269 176.965 153.009 1.00 76.12  ? 170 ARG A HB3  1 
ATOM   2445 H  HG2  . ARG A 1 159 ? 161.369 176.588 154.955 1.00 75.08  ? 170 ARG A HG2  1 
ATOM   2446 H  HG3  . ARG A 1 159 ? 162.454 176.494 153.799 1.00 75.62  ? 170 ARG A HG3  1 
ATOM   2447 H  HD2  . ARG A 1 159 ? 163.418 177.716 155.447 1.00 76.38  ? 170 ARG A HD2  1 
ATOM   2448 H  HD3  . ARG A 1 159 ? 163.036 178.764 154.316 1.00 76.10  ? 170 ARG A HD3  1 
ATOM   2449 H  HE   . ARG A 1 159 ? 161.516 179.624 155.661 1.00 76.23  ? 170 ARG A HE   1 
ATOM   2450 H  HH11 . ARG A 1 159 ? 161.891 177.104 158.439 1.00 76.56  ? 170 ARG A HH11 1 
ATOM   2451 H  HH12 . ARG A 1 159 ? 162.534 176.822 157.127 1.00 75.74  ? 170 ARG A HH12 1 
ATOM   2452 H  HH21 . ARG A 1 159 ? 160.647 180.056 157.692 1.00 76.60  ? 170 ARG A HH21 1 
ATOM   2453 H  HH22 . ARG A 1 159 ? 160.757 179.047 158.781 1.00 76.93  ? 170 ARG A HH22 1 
ATOM   2454 N  N    . PRO A 1 160 ? 163.628 177.491 151.110 1.00 74.41  ? 171 PRO A N    1 
ATOM   2455 C  CA   . PRO A 1 160 ? 164.439 176.446 150.458 1.00 72.39  ? 171 PRO A CA   1 
ATOM   2456 C  C    . PRO A 1 160 ? 164.443 175.131 151.219 1.00 73.32  ? 171 PRO A C    1 
ATOM   2457 O  O    . PRO A 1 160 ? 164.492 174.049 150.608 1.00 79.19  ? 171 PRO A O    1 
ATOM   2458 C  CB   . PRO A 1 160 ? 165.837 177.078 150.402 1.00 70.70  ? 171 PRO A CB   1 
ATOM   2459 C  CG   . PRO A 1 160 ? 165.838 178.069 151.514 1.00 71.54  ? 171 PRO A CG   1 
ATOM   2460 C  CD   . PRO A 1 160 ? 164.457 178.639 151.518 1.00 70.06  ? 171 PRO A CD   1 
ATOM   2461 H  HA   . PRO A 1 160 ? 164.121 176.294 149.555 1.00 73.32  ? 171 PRO A HA   1 
ATOM   2462 H  HB2  . PRO A 1 160 ? 166.512 176.397 150.545 1.00 73.09  ? 171 PRO A HB2  1 
ATOM   2463 H  HB3  . PRO A 1 160 ? 165.966 177.519 149.547 1.00 73.36  ? 171 PRO A HB3  1 
ATOM   2464 H  HG2  . PRO A 1 160 ? 166.030 177.623 152.354 1.00 73.29  ? 171 PRO A HG2  1 
ATOM   2465 H  HG3  . PRO A 1 160 ? 166.493 178.761 151.335 1.00 73.70  ? 171 PRO A HG3  1 
ATOM   2466 H  HD2  . PRO A 1 160 ? 164.222 178.932 152.412 1.00 73.19  ? 171 PRO A HD2  1 
ATOM   2467 H  HD3  . PRO A 1 160 ? 164.385 179.362 150.876 1.00 73.46  ? 171 PRO A HD3  1 
ATOM   2468 N  N    . ASP A 1 161 ? 164.395 175.191 152.551 1.00 72.12  ? 172 ASP A N    1 
ATOM   2469 C  CA   . ASP A 1 161 ? 164.271 173.966 153.327 1.00 73.28  ? 172 ASP A CA   1 
ATOM   2470 C  C    . ASP A 1 161 ? 163.079 173.155 152.843 1.00 71.93  ? 172 ASP A C    1 
ATOM   2471 O  O    . ASP A 1 161 ? 163.137 171.923 152.784 1.00 72.06  ? 172 ASP A O    1 
ATOM   2472 C  CB   . ASP A 1 161 ? 164.133 174.295 154.814 1.00 77.36  ? 172 ASP A CB   1 
ATOM   2473 C  CG   . ASP A 1 161 ? 165.411 174.849 155.411 1.00 81.88  ? 172 ASP A CG   1 
ATOM   2474 O  OD1  . ASP A 1 161 ? 166.441 174.143 155.378 1.00 83.78  ? 172 ASP A OD1  1 
ATOM   2475 O  OD2  . ASP A 1 161 ? 165.387 175.993 155.913 1.00 82.66  ? 172 ASP A OD2  1 
ATOM   2476 H  H    . ASP A 1 161 ? 164.436 175.913 153.016 1.00 75.77  ? 172 ASP A H    1 
ATOM   2477 H  HA   . ASP A 1 161 ? 165.071 173.428 153.209 1.00 76.09  ? 172 ASP A HA   1 
ATOM   2478 H  HB2  . ASP A 1 161 ? 163.429 174.947 154.942 1.00 76.09  ? 172 ASP A HB2  1 
ATOM   2479 H  HB3  . ASP A 1 161 ? 163.919 173.479 155.289 1.00 76.49  ? 172 ASP A HB3  1 
ATOM   2480 N  N    . TYR A 1 162 ? 161.990 173.834 152.474 1.00 69.14  ? 173 TYR A N    1 
ATOM   2481 C  CA   . TYR A 1 162 ? 160.828 173.125 151.952 1.00 67.43  ? 173 TYR A CA   1 
ATOM   2482 C  C    . TYR A 1 162 ? 161.133 172.448 150.622 1.00 74.58  ? 173 TYR A C    1 
ATOM   2483 O  O    . TYR A 1 162 ? 160.534 171.413 150.309 1.00 77.79  ? 173 TYR A O    1 
ATOM   2484 C  CB   . TYR A 1 162 ? 159.642 174.080 151.834 1.00 70.56  ? 173 TYR A CB   1 
ATOM   2485 C  CG   . TYR A 1 162 ? 158.792 174.068 153.080 1.00 68.32  ? 173 TYR A CG   1 
ATOM   2486 C  CD1  . TYR A 1 162 ? 159.310 174.489 154.295 1.00 66.80  ? 173 TYR A CD1  1 
ATOM   2487 C  CD2  . TYR A 1 162 ? 157.485 173.604 153.051 1.00 68.28  ? 173 TYR A CD2  1 
ATOM   2488 C  CE1  . TYR A 1 162 ? 158.550 174.469 155.439 1.00 67.43  ? 173 TYR A CE1  1 
ATOM   2489 C  CE2  . TYR A 1 162 ? 156.716 173.580 154.193 1.00 61.93  ? 173 TYR A CE2  1 
ATOM   2490 C  CZ   . TYR A 1 162 ? 157.255 174.012 155.384 1.00 65.95  ? 173 TYR A CZ   1 
ATOM   2491 O  OH   . TYR A 1 162 ? 156.498 173.991 156.530 1.00 77.66  ? 173 TYR A OH   1 
ATOM   2492 H  H    . TYR A 1 162 ? 161.905 174.689 152.513 1.00 70.80  ? 173 TYR A H    1 
ATOM   2493 H  HA   . TYR A 1 162 ? 160.567 172.434 152.572 1.00 69.51  ? 173 TYR A HA   1 
ATOM   2494 H  HB2  . TYR A 1 162 ? 159.969 174.982 151.702 1.00 70.56  ? 173 TYR A HB2  1 
ATOM   2495 H  HB3  . TYR A 1 162 ? 159.088 173.810 151.088 1.00 70.04  ? 173 TYR A HB3  1 
ATOM   2496 H  HD1  . TYR A 1 162 ? 160.186 174.797 154.335 1.00 70.12  ? 173 TYR A HD1  1 
ATOM   2497 H  HD2  . TYR A 1 162 ? 157.119 173.312 152.247 1.00 70.20  ? 173 TYR A HD2  1 
ATOM   2498 H  HE1  . TYR A 1 162 ? 158.909 174.759 156.247 1.00 70.03  ? 173 TYR A HE1  1 
ATOM   2499 H  HE2  . TYR A 1 162 ? 155.839 173.272 154.160 1.00 68.81  ? 173 TYR A HE2  1 
ATOM   2500 H  HH   . TYR A 1 162 ? 155.922 173.383 156.485 1.00 70.62  ? 173 TYR A HH   1 
ATOM   2501 N  N    . LEU A 1 163 ? 162.051 173.004 149.826 1.00 79.09  ? 174 LEU A N    1 
ATOM   2502 C  CA   . LEU A 1 163 ? 162.550 172.257 148.675 1.00 75.70  ? 174 LEU A CA   1 
ATOM   2503 C  C    . LEU A 1 163 ? 163.279 171.001 149.125 1.00 73.78  ? 174 LEU A C    1 
ATOM   2504 O  O    . LEU A 1 163 ? 163.163 169.946 148.490 1.00 76.65  ? 174 LEU A O    1 
ATOM   2505 C  CB   . LEU A 1 163 ? 163.473 173.121 147.818 1.00 70.72  ? 174 LEU A CB   1 
ATOM   2506 C  CG   . LEU A 1 163 ? 162.822 174.318 147.129 1.00 70.15  ? 174 LEU A CG   1 
ATOM   2507 C  CD1  . LEU A 1 163 ? 163.878 175.314 146.680 1.00 70.95  ? 174 LEU A CD1  1 
ATOM   2508 C  CD2  . LEU A 1 163 ? 161.964 173.865 145.954 1.00 72.54  ? 174 LEU A CD2  1 
ATOM   2509 H  H    . LEU A 1 163 ? 162.387 173.789 149.927 1.00 73.68  ? 174 LEU A H    1 
ATOM   2510 H  HA   . LEU A 1 163 ? 161.801 171.985 148.123 1.00 72.91  ? 174 LEU A HA   1 
ATOM   2511 H  HB2  . LEU A 1 163 ? 164.191 173.457 148.375 1.00 72.73  ? 174 LEU A HB2  1 
ATOM   2512 H  HB3  . LEU A 1 163 ? 163.847 172.557 147.123 1.00 73.11  ? 174 LEU A HB3  1 
ATOM   2513 H  HG   . LEU A 1 163 ? 162.244 174.765 147.767 1.00 72.67  ? 174 LEU A HG   1 
ATOM   2514 H  HD11 . LEU A 1 163 ? 163.447 176.010 146.159 1.00 73.23  ? 174 LEU A HD11 1 
ATOM   2515 H  HD12 . LEU A 1 163 ? 164.307 175.699 147.458 1.00 72.45  ? 174 LEU A HD12 1 
ATOM   2516 H  HD13 . LEU A 1 163 ? 164.534 174.855 146.133 1.00 72.64  ? 174 LEU A HD13 1 
ATOM   2517 H  HD21 . LEU A 1 163 ? 161.584 174.647 145.523 1.00 72.83  ? 174 LEU A HD21 1 
ATOM   2518 H  HD22 . LEU A 1 163 ? 162.518 173.377 145.324 1.00 73.47  ? 174 LEU A HD22 1 
ATOM   2519 H  HD23 . LEU A 1 163 ? 161.254 173.292 146.282 1.00 72.59  ? 174 LEU A HD23 1 
ATOM   2520 N  N    . ARG A 1 164 ? 164.048 171.095 150.213 1.00 63.63  ? 175 ARG A N    1 
ATOM   2521 C  CA   . ARG A 1 164 ? 164.726 169.903 150.719 1.00 63.28  ? 175 ARG A CA   1 
ATOM   2522 C  C    . ARG A 1 164 ? 163.737 168.827 151.155 1.00 65.38  ? 175 ARG A C    1 
ATOM   2523 O  O    . ARG A 1 164 ? 163.961 167.639 150.899 1.00 64.77  ? 175 ARG A O    1 
ATOM   2524 C  CB   . ARG A 1 164 ? 165.642 170.265 151.887 1.00 68.74  ? 175 ARG A CB   1 
ATOM   2525 C  CG   . ARG A 1 164 ? 166.777 171.205 151.518 1.00 66.57  ? 175 ARG A CG   1 
ATOM   2526 C  CD   . ARG A 1 164 ? 167.769 170.565 150.544 1.00 70.58  ? 175 ARG A CD   1 
ATOM   2527 N  NE   . ARG A 1 164 ? 167.952 169.132 150.752 1.00 73.79  ? 175 ARG A NE   1 
ATOM   2528 C  CZ   . ARG A 1 164 ? 168.408 168.582 151.870 1.00 69.72  ? 175 ARG A CZ   1 
ATOM   2529 N  NH1  . ARG A 1 164 ? 168.781 169.320 152.902 1.00 65.34  ? 175 ARG A NH1  1 
ATOM   2530 N  NH2  . ARG A 1 164 ? 168.499 167.258 151.951 1.00 66.81  ? 175 ARG A NH2  1 
ATOM   2531 H  H    . ARG A 1 164 ? 164.195 171.815 150.658 1.00 68.55  ? 175 ARG A H    1 
ATOM   2532 H  HA   . ARG A 1 164 ? 165.278 169.533 150.010 1.00 67.19  ? 175 ARG A HA   1 
ATOM   2533 H  HB2  . ARG A 1 164 ? 165.112 170.696 152.573 1.00 68.64  ? 175 ARG A HB2  1 
ATOM   2534 H  HB3  . ARG A 1 164 ? 166.018 169.449 152.246 1.00 68.27  ? 175 ARG A HB3  1 
ATOM   2535 H  HG2  . ARG A 1 164 ? 166.405 171.996 151.097 1.00 68.34  ? 175 ARG A HG2  1 
ATOM   2536 H  HG3  . ARG A 1 164 ? 167.254 171.454 152.324 1.00 67.37  ? 175 ARG A HG3  1 
ATOM   2537 H  HD2  . ARG A 1 164 ? 167.448 170.696 149.637 1.00 67.53  ? 175 ARG A HD2  1 
ATOM   2538 H  HD3  . ARG A 1 164 ? 168.633 170.991 150.652 1.00 68.55  ? 175 ARG A HD3  1 
ATOM   2539 H  HE   . ARG A 1 164 ? 167.737 168.604 150.107 1.00 68.05  ? 175 ARG A HE   1 
ATOM   2540 H  HH11 . ARG A 1 164 ? 168.731 170.177 152.863 1.00 67.30  ? 175 ARG A HH11 1 
ATOM   2541 H  HH12 . ARG A 1 164 ? 169.077 168.941 153.615 1.00 67.80  ? 175 ARG A HH12 1 
ATOM   2542 H  HH21 . ARG A 1 164 ? 168.260 166.768 151.287 1.00 67.41  ? 175 ARG A HH21 1 
ATOM   2543 H  HH22 . ARG A 1 164 ? 168.796 166.892 152.671 1.00 68.01  ? 175 ARG A HH22 1 
ATOM   2544 N  N    . LEU A 1 165 ? 162.640 169.222 151.807 1.00 68.55  ? 176 LEU A N    1 
ATOM   2545 C  CA   . LEU A 1 165 ? 161.677 168.243 152.322 1.00 65.02  ? 176 LEU A CA   1 
ATOM   2546 C  C    . LEU A 1 165 ? 161.219 167.241 151.271 1.00 63.96  ? 176 LEU A C    1 
ATOM   2547 O  O    . LEU A 1 165 ? 160.634 166.212 151.629 1.00 64.85  ? 176 LEU A O    1 
ATOM   2548 C  CB   . LEU A 1 165 ? 160.462 168.940 152.938 1.00 65.09  ? 176 LEU A CB   1 
ATOM   2549 C  CG   . LEU A 1 165 ? 160.644 169.481 154.354 1.00 70.82  ? 176 LEU A CG   1 
ATOM   2550 C  CD1  . LEU A 1 165 ? 161.677 170.537 154.481 1.00 69.46  ? 176 LEU A CD1  1 
ATOM   2551 C  CD2  . LEU A 1 165 ? 159.325 170.053 154.813 1.00 73.83  ? 176 LEU A CD2  1 
ATOM   2552 H  H    . LEU A 1 165 ? 162.429 170.041 151.960 1.00 67.99  ? 176 LEU A H    1 
ATOM   2553 H  HA   . LEU A 1 165 ? 162.106 167.742 153.033 1.00 66.82  ? 176 LEU A HA   1 
ATOM   2554 H  HB2  . LEU A 1 165 ? 160.208 169.685 152.370 1.00 67.37  ? 176 LEU A HB2  1 
ATOM   2555 H  HB3  . LEU A 1 165 ? 159.728 168.304 152.974 1.00 66.56  ? 176 LEU A HB3  1 
ATOM   2556 H  HG   . LEU A 1 165 ? 160.887 168.751 154.944 1.00 67.57  ? 176 LEU A HG   1 
ATOM   2557 H  HD11 . LEU A 1 165 ? 161.820 170.708 155.420 1.00 67.32  ? 176 LEU A HD11 1 
ATOM   2558 H  HD12 . LEU A 1 165 ? 162.499 170.215 154.081 1.00 67.51  ? 176 LEU A HD12 1 
ATOM   2559 H  HD13 . LEU A 1 165 ? 161.363 171.339 154.048 1.00 67.67  ? 176 LEU A HD13 1 
ATOM   2560 H  HD21 . LEU A 1 165 ? 159.405 170.277 155.750 1.00 67.54  ? 176 LEU A HD21 1 
ATOM   2561 H  HD22 . LEU A 1 165 ? 159.139 170.852 154.298 1.00 67.60  ? 176 LEU A HD22 1 
ATOM   2562 H  HD23 . LEU A 1 165 ? 158.624 169.396 154.676 1.00 67.36  ? 176 LEU A HD23 1 
ATOM   2563 N  N    . GLY A 1 166 ? 161.474 167.498 149.990 1.00 54.59  ? 177 GLY A N    1 
ATOM   2564 C  CA   . GLY A 1 166 ? 161.328 166.434 149.014 1.00 61.15  ? 177 GLY A CA   1 
ATOM   2565 C  C    . GLY A 1 166 ? 162.190 165.238 149.367 1.00 62.79  ? 177 GLY A C    1 
ATOM   2566 O  O    . GLY A 1 166 ? 161.766 164.088 149.226 1.00 58.96  ? 177 GLY A O    1 
ATOM   2567 H  H    . GLY A 1 166 ? 161.717 168.260 149.671 1.00 60.16  ? 177 GLY A H    1 
ATOM   2568 H  HA2  . GLY A 1 166 ? 160.400 166.153 148.976 1.00 60.67  ? 177 GLY A HA2  1 
ATOM   2569 H  HA3  . GLY A 1 166 ? 161.590 166.756 148.137 1.00 61.18  ? 177 GLY A HA3  1 
ATOM   2570 N  N    . ALA A 1 167 ? 163.404 165.496 149.858 1.00 74.48  ? 178 ALA A N    1 
ATOM   2571 C  CA   . ALA A 1 167 ? 164.266 164.412 150.317 1.00 74.79  ? 178 ALA A CA   1 
ATOM   2572 C  C    . ALA A 1 167 ? 163.662 163.693 151.517 1.00 72.82  ? 178 ALA A C    1 
ATOM   2573 O  O    . ALA A 1 167 ? 163.690 162.459 151.587 1.00 72.36  ? 178 ALA A O    1 
ATOM   2574 C  CB   . ALA A 1 167 ? 165.652 164.956 150.663 1.00 74.32  ? 178 ALA A CB   1 
ATOM   2575 H  H    . ALA A 1 167 ? 163.748 166.281 149.931 1.00 71.80  ? 178 ALA A H    1 
ATOM   2576 H  HA   . ALA A 1 167 ? 164.369 163.766 149.600 1.00 71.95  ? 178 ALA A HA   1 
ATOM   2577 H  HB1  . ALA A 1 167 ? 166.218 164.220 150.945 1.00 72.29  ? 178 ALA A HB1  1 
ATOM   2578 H  HB2  . ALA A 1 167 ? 166.030 165.384 149.880 1.00 72.47  ? 178 ALA A HB2  1 
ATOM   2579 H  HB3  . ALA A 1 167 ? 165.567 165.602 151.383 1.00 71.92  ? 178 ALA A HB3  1 
ATOM   2580 N  N    . LEU A 1 168 ? 163.113 164.445 152.475 1.00 67.66  ? 179 LEU A N    1 
ATOM   2581 C  CA   . LEU A 1 168 ? 162.491 163.811 153.633 1.00 69.30  ? 179 LEU A CA   1 
ATOM   2582 C  C    . LEU A 1 168 ? 161.340 162.915 153.202 1.00 70.39  ? 179 LEU A C    1 
ATOM   2583 O  O    . LEU A 1 168 ? 161.164 161.814 153.736 1.00 70.52  ? 179 LEU A O    1 
ATOM   2584 C  CB   . LEU A 1 168 ? 162.005 164.871 154.625 1.00 62.59  ? 179 LEU A CB   1 
ATOM   2585 C  CG   . LEU A 1 168 ? 161.152 164.375 155.800 1.00 61.85  ? 179 LEU A CG   1 
ATOM   2586 C  CD1  . LEU A 1 168 ? 161.999 163.591 156.787 1.00 63.33  ? 179 LEU A CD1  1 
ATOM   2587 C  CD2  . LEU A 1 168 ? 160.459 165.535 156.499 1.00 62.78  ? 179 LEU A CD2  1 
ATOM   2588 H  H    . LEU A 1 168 ? 163.086 165.305 152.477 1.00 65.57  ? 179 LEU A H    1 
ATOM   2589 H  HA   . LEU A 1 168 ? 163.148 163.257 154.083 1.00 65.77  ? 179 LEU A HA   1 
ATOM   2590 H  HB2  . LEU A 1 168 ? 162.782 165.312 155.001 1.00 64.80  ? 179 LEU A HB2  1 
ATOM   2591 H  HB3  . LEU A 1 168 ? 161.472 165.519 154.138 1.00 64.67  ? 179 LEU A HB3  1 
ATOM   2592 H  HG   . LEU A 1 168 ? 160.459 163.783 155.471 1.00 64.44  ? 179 LEU A HG   1 
ATOM   2593 H  HD11 . LEU A 1 168 ? 161.450 163.349 157.549 1.00 65.26  ? 179 LEU A HD11 1 
ATOM   2594 H  HD12 . LEU A 1 168 ? 162.332 162.791 156.352 1.00 64.78  ? 179 LEU A HD12 1 
ATOM   2595 H  HD13 . LEU A 1 168 ? 162.741 164.145 157.077 1.00 65.51  ? 179 LEU A HD13 1 
ATOM   2596 H  HD21 . LEU A 1 168 ? 159.969 165.193 157.263 1.00 64.08  ? 179 LEU A HD21 1 
ATOM   2597 H  HD22 . LEU A 1 168 ? 161.128 166.172 156.793 1.00 65.09  ? 179 LEU A HD22 1 
ATOM   2598 H  HD23 . LEU A 1 168 ? 159.847 165.959 155.877 1.00 63.88  ? 179 LEU A HD23 1 
ATOM   2599 N  N    . ARG A 1 169 ? 160.541 163.373 152.238 1.00 56.49  ? 180 ARG A N    1 
ATOM   2600 C  CA   . ARG A 1 169 ? 159.467 162.532 151.725 1.00 47.58  ? 180 ARG A CA   1 
ATOM   2601 C  C    . ARG A 1 169 ? 160.029 161.304 151.024 1.00 48.52  ? 180 ARG A C    1 
ATOM   2602 O  O    . ARG A 1 169 ? 159.446 160.216 151.101 1.00 52.11  ? 180 ARG A O    1 
ATOM   2603 C  CB   . ARG A 1 169 ? 158.574 163.321 150.770 1.00 49.30  ? 180 ARG A CB   1 
ATOM   2604 C  CG   . ARG A 1 169 ? 157.421 162.498 150.207 1.00 43.86  ? 180 ARG A CG   1 
ATOM   2605 C  CD   . ARG A 1 169 ? 156.498 162.039 151.314 1.00 41.92  ? 180 ARG A CD   1 
ATOM   2606 N  NE   . ARG A 1 169 ? 155.413 161.193 150.836 1.00 46.86  ? 180 ARG A NE   1 
ATOM   2607 C  CZ   . ARG A 1 169 ? 155.505 159.881 150.677 1.00 48.25  ? 180 ARG A CZ   1 
ATOM   2608 N  NH1  . ARG A 1 169 ? 156.635 159.232 150.906 1.00 50.57  ? 180 ARG A NH1  1 
ATOM   2609 N  NH2  . ARG A 1 169 ? 154.434 159.198 150.285 1.00 48.35  ? 180 ARG A NH2  1 
ATOM   2610 H  H    . ARG A 1 169 ? 160.599 164.149 151.873 1.00 52.60  ? 180 ARG A H    1 
ATOM   2611 H  HA   . ARG A 1 169 ? 158.931 162.233 152.475 1.00 48.67  ? 180 ARG A HA   1 
ATOM   2612 H  HB2  . ARG A 1 169 ? 158.197 164.078 151.245 1.00 49.48  ? 180 ARG A HB2  1 
ATOM   2613 H  HB3  . ARG A 1 169 ? 159.111 163.632 150.025 1.00 51.21  ? 180 ARG A HB3  1 
ATOM   2614 H  HG2  . ARG A 1 169 ? 156.904 163.042 149.594 1.00 49.19  ? 180 ARG A HG2  1 
ATOM   2615 H  HG3  . ARG A 1 169 ? 157.766 161.716 149.750 1.00 48.01  ? 180 ARG A HG3  1 
ATOM   2616 H  HD2  . ARG A 1 169 ? 156.998 161.532 151.970 1.00 47.26  ? 180 ARG A HD2  1 
ATOM   2617 H  HD3  . ARG A 1 169 ? 156.109 162.823 151.730 1.00 48.11  ? 180 ARG A HD3  1 
ATOM   2618 H  HE   . ARG A 1 169 ? 154.734 161.585 150.483 1.00 49.32  ? 180 ARG A HE   1 
ATOM   2619 H  HH11 . ARG A 1 169 ? 157.336 159.659 151.162 1.00 48.92  ? 180 ARG A HH11 1 
ATOM   2620 H  HH12 . ARG A 1 169 ? 156.667 158.381 150.794 1.00 49.34  ? 180 ARG A HH12 1 
ATOM   2621 H  HH21 . ARG A 1 169 ? 153.694 159.608 150.133 1.00 48.96  ? 180 ARG A HH21 1 
ATOM   2622 H  HH22 . ARG A 1 169 ? 154.483 158.347 150.177 1.00 48.69  ? 180 ARG A HH22 1 
ATOM   2623 N  N    . SER A 1 170 ? 161.147 161.462 150.312 1.00 47.97  ? 181 SER A N    1 
ATOM   2624 C  CA   . SER A 1 170 ? 161.794 160.302 149.709 1.00 51.82  ? 181 SER A CA   1 
ATOM   2625 C  C    . SER A 1 170 ? 162.156 159.280 150.777 1.00 57.04  ? 181 SER A C    1 
ATOM   2626 O  O    . SER A 1 170 ? 161.877 158.084 150.626 1.00 58.59  ? 181 SER A O    1 
ATOM   2627 C  CB   . SER A 1 170 ? 163.038 160.736 148.934 1.00 54.87  ? 181 SER A CB   1 
ATOM   2628 O  OG   . SER A 1 170 ? 162.730 161.759 148.004 1.00 57.43  ? 181 SER A OG   1 
ATOM   2629 H  H    . SER A 1 170 ? 161.540 162.213 150.167 1.00 54.71  ? 181 SER A H    1 
ATOM   2630 H  HA   . SER A 1 170 ? 161.179 159.885 149.086 1.00 54.73  ? 181 SER A HA   1 
ATOM   2631 H  HB2  . SER A 1 170 ? 163.703 161.065 149.559 1.00 55.59  ? 181 SER A HB2  1 
ATOM   2632 H  HB3  . SER A 1 170 ? 163.387 159.970 148.452 1.00 55.54  ? 181 SER A HB3  1 
ATOM   2633 H  HG   . SER A 1 170 ? 163.405 161.935 147.536 1.00 56.35  ? 181 SER A HG   1 
ATOM   2634 N  N    . ARG A 1 171 ? 162.764 159.735 151.869 1.00 66.94  ? 182 ARG A N    1 
ATOM   2635 C  CA   . ARG A 1 171 ? 162.885 158.917 153.062 1.00 63.45  ? 182 ARG A CA   1 
ATOM   2636 C  C    . ARG A 1 171 ? 161.493 158.552 153.570 1.00 57.70  ? 182 ARG A C    1 
ATOM   2637 O  O    . ARG A 1 171 ? 160.476 159.039 153.073 1.00 59.11  ? 182 ARG A O    1 
ATOM   2638 C  CB   . ARG A 1 171 ? 163.655 159.666 154.148 1.00 64.24  ? 182 ARG A CB   1 
ATOM   2639 C  CG   . ARG A 1 171 ? 165.084 160.031 153.784 1.00 66.82  ? 182 ARG A CG   1 
ATOM   2640 C  CD   . ARG A 1 171 ? 165.956 158.796 153.635 1.00 70.39  ? 182 ARG A CD   1 
ATOM   2641 N  NE   . ARG A 1 171 ? 166.091 158.082 154.899 1.00 71.19  ? 182 ARG A NE   1 
ATOM   2642 C  CZ   . ARG A 1 171 ? 166.511 156.830 155.017 1.00 70.61  ? 182 ARG A CZ   1 
ATOM   2643 N  NH1  . ARG A 1 171 ? 166.848 156.110 153.959 1.00 71.09  ? 182 ARG A NH1  1 
ATOM   2644 N  NH2  . ARG A 1 171 ? 166.596 156.285 156.227 1.00 64.61  ? 182 ARG A NH2  1 
ATOM   2645 H  H    . ARG A 1 171 ? 163.113 160.518 151.942 1.00 65.12  ? 182 ARG A H    1 
ATOM   2646 H  HA   . ARG A 1 171 ? 163.358 158.098 152.848 1.00 64.63  ? 182 ARG A HA   1 
ATOM   2647 H  HB2  . ARG A 1 171 ? 163.184 160.490 154.348 1.00 65.38  ? 182 ARG A HB2  1 
ATOM   2648 H  HB3  . ARG A 1 171 ? 163.688 159.110 154.943 1.00 65.94  ? 182 ARG A HB3  1 
ATOM   2649 H  HG2  . ARG A 1 171 ? 165.086 160.510 152.940 1.00 65.42  ? 182 ARG A HG2  1 
ATOM   2650 H  HG3  . ARG A 1 171 ? 165.459 160.586 154.485 1.00 66.52  ? 182 ARG A HG3  1 
ATOM   2651 H  HD2  . ARG A 1 171 ? 165.557 158.196 152.986 1.00 65.91  ? 182 ARG A HD2  1 
ATOM   2652 H  HD3  . ARG A 1 171 ? 166.841 159.064 153.342 1.00 66.55  ? 182 ARG A HD3  1 
ATOM   2653 H  HE   . ARG A 1 171 ? 165.858 158.494 155.618 1.00 66.37  ? 182 ARG A HE   1 
ATOM   2654 H  HH11 . ARG A 1 171 ? 166.798 156.450 153.171 1.00 66.25  ? 182 ARG A HH11 1 
ATOM   2655 H  HH12 . ARG A 1 171 ? 167.117 155.300 154.060 1.00 66.36  ? 182 ARG A HH12 1 
ATOM   2656 H  HH21 . ARG A 1 171 ? 166.379 156.744 156.922 1.00 66.35  ? 182 ARG A HH21 1 
ATOM   2657 H  HH22 . ARG A 1 171 ? 166.866 155.474 156.316 1.00 65.73  ? 182 ARG A HH22 1 
ATOM   2658 N  N    . LEU A 1 172 ? 161.455 157.682 154.578 1.00 44.24  ? 183 LEU A N    1 
ATOM   2659 C  CA   . LEU A 1 172 ? 160.205 157.348 155.253 1.00 47.48  ? 183 LEU A CA   1 
ATOM   2660 C  C    . LEU A 1 172 ? 159.069 157.141 154.257 1.00 50.72  ? 183 LEU A C    1 
ATOM   2661 O  O    . LEU A 1 172 ? 157.916 157.483 154.536 1.00 54.06  ? 183 LEU A O    1 
ATOM   2662 C  CB   . LEU A 1 172 ? 159.847 158.441 156.274 1.00 60.42  ? 183 LEU A CB   1 
ATOM   2663 C  CG   . LEU A 1 172 ? 159.597 159.895 155.823 1.00 63.83  ? 183 LEU A CG   1 
ATOM   2664 C  CD1  . LEU A 1 172 ? 158.174 160.121 155.325 1.00 55.14  ? 183 LEU A CD1  1 
ATOM   2665 C  CD2  . LEU A 1 172 ? 159.928 160.898 156.929 1.00 59.31  ? 183 LEU A CD2  1 
ATOM   2666 H  H    . LEU A 1 172 ? 162.143 157.269 154.889 1.00 56.21  ? 183 LEU A H    1 
ATOM   2667 H  HA   . LEU A 1 172 ? 160.328 156.518 155.740 1.00 55.34  ? 183 LEU A HA   1 
ATOM   2668 H  HB2  . LEU A 1 172 ? 159.038 158.148 156.716 1.00 56.68  ? 183 LEU A HB2  1 
ATOM   2669 H  HB3  . LEU A 1 172 ? 160.562 158.474 156.928 1.00 57.46  ? 183 LEU A HB3  1 
ATOM   2670 H  HG   . LEU A 1 172 ? 160.190 160.103 155.092 1.00 57.32  ? 183 LEU A HG   1 
ATOM   2671 H  HD11 . LEU A 1 172 ? 157.939 161.052 155.466 1.00 55.57  ? 183 LEU A HD11 1 
ATOM   2672 H  HD12 . LEU A 1 172 ? 158.133 159.912 154.378 1.00 54.66  ? 183 LEU A HD12 1 
ATOM   2673 H  HD13 . LEU A 1 172 ? 157.565 159.551 155.821 1.00 55.92  ? 183 LEU A HD13 1 
ATOM   2674 H  HD21 . LEU A 1 172 ? 159.867 161.794 156.561 1.00 56.40  ? 183 LEU A HD21 1 
ATOM   2675 H  HD22 . LEU A 1 172 ? 159.294 160.803 157.653 1.00 55.61  ? 183 LEU A HD22 1 
ATOM   2676 H  HD23 . LEU A 1 172 ? 160.828 160.736 157.251 1.00 57.15  ? 183 LEU A HD23 1 
ATOM   2677 N  N    . GLY A 1 173 ? 159.384 156.551 153.102 1.00 49.49  ? 184 GLY A N    1 
ATOM   2678 C  CA   . GLY A 1 173 ? 158.395 156.444 152.041 1.00 54.79  ? 184 GLY A CA   1 
ATOM   2679 C  C    . GLY A 1 173 ? 157.158 155.673 152.458 1.00 51.70  ? 184 GLY A C    1 
ATOM   2680 O  O    . GLY A 1 173 ? 156.046 155.986 152.027 1.00 58.62  ? 184 GLY A O    1 
ATOM   2681 H  H    . GLY A 1 173 ? 160.153 156.215 152.913 1.00 54.22  ? 184 GLY A H    1 
ATOM   2682 H  HA2  . GLY A 1 173 ? 158.124 157.334 151.771 1.00 54.65  ? 184 GLY A HA2  1 
ATOM   2683 H  HA3  . GLY A 1 173 ? 158.790 155.998 151.276 1.00 54.47  ? 184 GLY A HA3  1 
ATOM   2684 N  N    . HIS A 1 174 ? 157.333 154.651 153.297 1.00 48.82  ? 185 HIS A N    1 
ATOM   2685 C  CA   . HIS A 1 174 ? 156.200 153.840 153.727 1.00 43.21  ? 185 HIS A CA   1 
ATOM   2686 C  C    . HIS A 1 174 ? 155.090 154.701 154.314 1.00 47.39  ? 185 HIS A C    1 
ATOM   2687 O  O    . HIS A 1 174 ? 153.904 154.386 154.167 1.00 53.40  ? 185 HIS A O    1 
ATOM   2688 C  CB   . HIS A 1 174 ? 156.671 152.802 154.746 1.00 50.63  ? 185 HIS A CB   1 
ATOM   2689 C  CG   . HIS A 1 174 ? 157.103 153.395 156.051 1.00 58.69  ? 185 HIS A CG   1 
ATOM   2690 N  ND1  . HIS A 1 174 ? 158.199 154.223 156.163 1.00 62.29  ? 185 HIS A ND1  1 
ATOM   2691 C  CD2  . HIS A 1 174 ? 156.592 153.277 157.299 1.00 57.58  ? 185 HIS A CD2  1 
ATOM   2692 C  CE1  . HIS A 1 174 ? 158.342 154.594 157.422 1.00 61.69  ? 185 HIS A CE1  1 
ATOM   2693 N  NE2  . HIS A 1 174 ? 157.380 154.033 158.133 1.00 61.71  ? 185 HIS A NE2  1 
ATOM   2694 H  H    . HIS A 1 174 ? 158.090 154.410 153.627 1.00 55.18  ? 185 HIS A H    1 
ATOM   2695 H  HA   . HIS A 1 174 ? 155.840 153.367 152.960 1.00 53.16  ? 185 HIS A HA   1 
ATOM   2696 H  HB2  . HIS A 1 174 ? 155.944 152.185 154.924 1.00 54.22  ? 185 HIS A HB2  1 
ATOM   2697 H  HB3  . HIS A 1 174 ? 157.427 152.322 154.374 1.00 54.03  ? 185 HIS A HB3  1 
ATOM   2698 H  HD2  . HIS A 1 174 ? 155.846 152.780 157.546 1.00 55.00  ? 185 HIS A HD2  1 
ATOM   2699 H  HE1  . HIS A 1 174 ? 159.007 155.154 157.752 1.00 56.58  ? 185 HIS A HE1  1 
ATOM   2700 H  HE2  . HIS A 1 174 ? 157.266 154.126 158.980 1.00 56.46  ? 185 HIS A HE2  1 
ATOM   2701 N  N    . ALA A 1 175 ? 155.453 155.785 154.981 1.00 43.72  ? 186 ALA A N    1 
ATOM   2702 C  CA   . ALA A 1 175 ? 154.469 156.632 155.643 1.00 42.92  ? 186 ALA A CA   1 
ATOM   2703 C  C    . ALA A 1 175 ? 153.782 157.541 154.628 1.00 33.29  ? 186 ALA A C    1 
ATOM   2704 O  O    . ALA A 1 175 ? 154.464 158.232 153.866 1.00 29.23  ? 186 ALA A O    1 
ATOM   2705 C  CB   . ALA A 1 175 ? 155.134 157.477 156.722 1.00 49.43  ? 186 ALA A CB   1 
ATOM   2706 H  H    . ALA A 1 175 ? 156.265 156.056 155.067 1.00 45.88  ? 186 ALA A H    1 
ATOM   2707 H  HA   . ALA A 1 175 ? 153.810 156.068 156.073 1.00 45.12  ? 186 ALA A HA   1 
ATOM   2708 H  HB1  . ALA A 1 175 ? 154.451 157.945 157.226 1.00 45.83  ? 186 ALA A HB1  1 
ATOM   2709 H  HB2  . ALA A 1 175 ? 155.640 156.893 157.307 1.00 47.53  ? 186 ALA A HB2  1 
ATOM   2710 H  HB3  . ALA A 1 175 ? 155.731 158.112 156.297 1.00 46.64  ? 186 ALA A HB3  1 
ATOM   2711 N  N    . PRO A 1 176 ? 152.449 157.569 154.584 1.00 34.32  ? 187 PRO A N    1 
ATOM   2712 C  CA   . PRO A 1 176 ? 151.770 158.566 153.750 1.00 43.09  ? 187 PRO A CA   1 
ATOM   2713 C  C    . PRO A 1 176 ? 152.083 159.980 154.214 1.00 38.24  ? 187 PRO A C    1 
ATOM   2714 O  O    . PRO A 1 176 ? 152.321 160.233 155.397 1.00 48.88  ? 187 PRO A O    1 
ATOM   2715 C  CB   . PRO A 1 176 ? 150.285 158.230 153.933 1.00 42.59  ? 187 PRO A CB   1 
ATOM   2716 C  CG   . PRO A 1 176 ? 150.274 156.810 154.368 1.00 38.29  ? 187 PRO A CG   1 
ATOM   2717 C  CD   . PRO A 1 176 ? 151.483 156.668 155.231 1.00 34.86  ? 187 PRO A CD   1 
ATOM   2718 H  HA   . PRO A 1 176 ? 152.018 158.462 152.818 1.00 43.15  ? 187 PRO A HA   1 
ATOM   2719 H  HB2  . PRO A 1 176 ? 149.900 158.802 154.615 1.00 42.79  ? 187 PRO A HB2  1 
ATOM   2720 H  HB3  . PRO A 1 176 ? 149.818 158.335 153.089 1.00 42.03  ? 187 PRO A HB3  1 
ATOM   2721 H  HG2  . PRO A 1 176 ? 149.468 156.628 154.875 1.00 42.39  ? 187 PRO A HG2  1 
ATOM   2722 H  HG3  . PRO A 1 176 ? 150.333 156.229 153.594 1.00 41.67  ? 187 PRO A HG3  1 
ATOM   2723 H  HD2  . PRO A 1 176 ? 151.291 156.966 156.132 1.00 42.34  ? 187 PRO A HD2  1 
ATOM   2724 H  HD3  . PRO A 1 176 ? 151.803 155.753 155.214 1.00 41.59  ? 187 PRO A HD3  1 
ATOM   2725 N  N    . CYS A 1 177 ? 152.082 160.907 153.261 1.00 31.21  ? 188 CYS A N    1 
ATOM   2726 C  CA   . CYS A 1 177 ? 152.407 162.300 153.524 1.00 37.88  ? 188 CYS A CA   1 
ATOM   2727 C  C    . CYS A 1 177 ? 151.197 163.187 153.272 1.00 36.08  ? 188 CYS A C    1 
ATOM   2728 O  O    . CYS A 1 177 ? 150.405 162.936 152.358 1.00 46.30  ? 188 CYS A O    1 
ATOM   2729 C  CB   . CYS A 1 177 ? 153.574 162.765 152.656 1.00 45.12  ? 188 CYS A CB   1 
ATOM   2730 S  SG   . CYS A 1 177 ? 153.913 164.535 152.771 1.00 44.43  ? 188 CYS A SG   1 
ATOM   2731 H  H    . CYS A 1 177 ? 151.891 160.748 152.438 1.00 41.73  ? 188 CYS A H    1 
ATOM   2732 H  HA   . CYS A 1 177 ? 152.666 162.400 154.453 1.00 43.44  ? 188 CYS A HA   1 
ATOM   2733 H  HB2  . CYS A 1 177 ? 154.370 162.293 152.943 1.00 44.05  ? 188 CYS A HB2  1 
ATOM   2734 H  HB3  . CYS A 1 177 ? 153.378 162.559 151.730 1.00 43.08  ? 188 CYS A HB3  1 
ATOM   2735 H  HG   . CYS A 1 177 ? 154.175 164.803 153.911 1.00 43.28  ? 188 CYS A HG   1 
ATOM   2736 N  N    . VAL A 1 178 ? 151.066 164.223 154.094 1.00 42.82  ? 189 VAL A N    1 
ATOM   2737 C  CA   . VAL A 1 178 ? 149.980 165.188 154.006 1.00 41.83  ? 189 VAL A CA   1 
ATOM   2738 C  C    . VAL A 1 178 ? 150.608 166.570 153.905 1.00 43.53  ? 189 VAL A C    1 
ATOM   2739 O  O    . VAL A 1 178 ? 151.242 167.043 154.856 1.00 50.19  ? 189 VAL A O    1 
ATOM   2740 C  CB   . VAL A 1 178 ? 149.038 165.102 155.213 1.00 51.39  ? 189 VAL A CB   1 
ATOM   2741 C  CG1  . VAL A 1 178 ? 147.856 166.044 155.032 1.00 53.74  ? 189 VAL A CG1  1 
ATOM   2742 C  CG2  . VAL A 1 178 ? 148.567 163.678 155.413 1.00 50.32  ? 189 VAL A CG2  1 
ATOM   2743 H  H    . VAL A 1 178 ? 151.616 164.392 154.733 1.00 49.16  ? 189 VAL A H    1 
ATOM   2744 H  HA   . VAL A 1 178 ? 149.465 165.022 153.204 1.00 47.99  ? 189 VAL A HA   1 
ATOM   2745 H  HB   . VAL A 1 178 ? 149.519 165.373 156.010 1.00 49.73  ? 189 VAL A HB   1 
ATOM   2746 H  HG11 . VAL A 1 178 ? 147.190 165.850 155.710 1.00 49.88  ? 189 VAL A HG11 1 
ATOM   2747 H  HG12 . VAL A 1 178 ? 148.164 166.959 155.125 1.00 49.60  ? 189 VAL A HG12 1 
ATOM   2748 H  HG13 . VAL A 1 178 ? 147.479 165.909 154.149 1.00 49.79  ? 189 VAL A HG13 1 
ATOM   2749 H  HG21 . VAL A 1 178 ? 147.866 163.677 156.080 1.00 49.71  ? 189 VAL A HG21 1 
ATOM   2750 H  HG22 . VAL A 1 178 ? 148.226 163.336 154.572 1.00 48.54  ? 189 VAL A HG22 1 
ATOM   2751 H  HG23 . VAL A 1 178 ? 149.313 163.135 155.713 1.00 49.00  ? 189 VAL A HG23 1 
ATOM   2752 N  N    . ALA A 1 179 ? 150.427 167.219 152.764 1.00 43.65  ? 190 ALA A N    1 
ATOM   2753 C  CA   . ALA A 1 179 ? 150.874 168.588 152.565 1.00 48.05  ? 190 ALA A CA   1 
ATOM   2754 C  C    . ALA A 1 179 ? 149.718 169.536 152.851 1.00 58.91  ? 190 ALA A C    1 
ATOM   2755 O  O    . ALA A 1 179 ? 148.573 169.261 152.480 1.00 66.41  ? 190 ALA A O    1 
ATOM   2756 C  CB   . ALA A 1 179 ? 151.391 168.795 151.141 1.00 56.52  ? 190 ALA A CB   1 
ATOM   2757 H  H    . ALA A 1 179 ? 150.039 166.880 152.075 1.00 52.34  ? 190 ALA A H    1 
ATOM   2758 H  HA   . ALA A 1 179 ? 151.594 168.788 153.183 1.00 52.93  ? 190 ALA A HA   1 
ATOM   2759 H  HB1  . ALA A 1 179 ? 151.600 169.733 151.013 1.00 54.56  ? 190 ALA A HB1  1 
ATOM   2760 H  HB2  . ALA A 1 179 ? 152.188 168.257 151.014 1.00 54.18  ? 190 ALA A HB2  1 
ATOM   2761 H  HB3  . ALA A 1 179 ? 150.704 168.520 150.515 1.00 53.99  ? 190 ALA A HB3  1 
ATOM   2762 N  N    . LEU A 1 180 ? 150.018 170.647 153.520 1.00 60.72  ? 191 LEU A N    1 
ATOM   2763 C  CA   . LEU A 1 180 ? 148.995 171.583 153.956 1.00 56.73  ? 191 LEU A CA   1 
ATOM   2764 C  C    . LEU A 1 180 ? 149.413 172.999 153.595 1.00 56.21  ? 191 LEU A C    1 
ATOM   2765 O  O    . LEU A 1 180 ? 150.595 173.348 153.652 1.00 64.44  ? 191 LEU A O    1 
ATOM   2766 C  CB   . LEU A 1 180 ? 148.768 171.484 155.464 1.00 56.74  ? 191 LEU A CB   1 
ATOM   2767 C  CG   . LEU A 1 180 ? 148.392 170.098 155.987 1.00 53.15  ? 191 LEU A CG   1 
ATOM   2768 C  CD1  . LEU A 1 180 ? 148.290 170.135 157.490 1.00 58.42  ? 191 LEU A CD1  1 
ATOM   2769 C  CD2  . LEU A 1 180 ? 147.095 169.605 155.389 1.00 53.50  ? 191 LEU A CD2  1 
ATOM   2770 H  H    . LEU A 1 180 ? 150.817 170.880 153.734 1.00 58.19  ? 191 LEU A H    1 
ATOM   2771 H  HA   . LEU A 1 180 ? 148.159 171.389 153.505 1.00 57.24  ? 191 LEU A HA   1 
ATOM   2772 H  HB2  . LEU A 1 180 ? 149.583 171.753 155.915 1.00 58.61  ? 191 LEU A HB2  1 
ATOM   2773 H  HB3  . LEU A 1 180 ? 148.050 172.089 155.705 1.00 58.06  ? 191 LEU A HB3  1 
ATOM   2774 H  HG   . LEU A 1 180 ? 149.091 169.469 155.748 1.00 57.10  ? 191 LEU A HG   1 
ATOM   2775 H  HD11 . LEU A 1 180 ? 147.447 169.734 157.753 1.00 59.08  ? 191 LEU A HD11 1 
ATOM   2776 H  HD12 . LEU A 1 180 ? 149.030 169.635 157.870 1.00 59.30  ? 191 LEU A HD12 1 
ATOM   2777 H  HD13 . LEU A 1 180 ? 148.324 171.058 157.787 1.00 59.09  ? 191 LEU A HD13 1 
ATOM   2778 H  HD21 . LEU A 1 180 ? 146.877 168.742 155.774 1.00 57.55  ? 191 LEU A HD21 1 
ATOM   2779 H  HD22 . LEU A 1 180 ? 146.394 170.243 155.593 1.00 58.42  ? 191 LEU A HD22 1 
ATOM   2780 H  HD23 . LEU A 1 180 ? 147.201 169.521 154.429 1.00 56.82  ? 191 LEU A HD23 1 
ATOM   2781 N  N    . THR A 1 181 ? 148.430 173.815 153.225 1.00 53.77  ? 192 THR A N    1 
ATOM   2782 C  CA   . THR A 1 181 ? 148.706 175.204 152.889 1.00 59.62  ? 192 THR A CA   1 
ATOM   2783 C  C    . THR A 1 181 ? 147.441 176.027 153.075 1.00 66.29  ? 192 THR A C    1 
ATOM   2784 O  O    . THR A 1 181 ? 146.332 175.491 153.140 1.00 70.30  ? 192 THR A O    1 
ATOM   2785 C  CB   . THR A 1 181 ? 149.228 175.342 151.455 1.00 62.66  ? 192 THR A CB   1 
ATOM   2786 O  OG1  . THR A 1 181 ? 149.761 176.658 151.263 1.00 64.65  ? 192 THR A OG1  1 
ATOM   2787 C  CG2  . THR A 1 181 ? 148.114 175.092 150.455 1.00 64.88  ? 192 THR A CG2  1 
ATOM   2788 H  H    . THR A 1 181 ? 147.602 173.591 153.162 1.00 62.81  ? 192 THR A H    1 
ATOM   2789 H  HA   . THR A 1 181 ? 149.383 175.550 153.491 1.00 63.62  ? 192 THR A HA   1 
ATOM   2790 H  HB   . THR A 1 181 ? 149.927 174.686 151.304 1.00 63.85  ? 192 THR A HB   1 
ATOM   2791 H  HG1  . THR A 1 181 ? 150.395 176.792 151.797 1.00 64.07  ? 192 THR A HG1  1 
ATOM   2792 H  HG21 . THR A 1 181 ? 148.490 174.786 149.616 1.00 63.23  ? 192 THR A HG21 1 
ATOM   2793 H  HG22 . THR A 1 181 ? 147.511 174.413 150.794 1.00 64.44  ? 192 THR A HG22 1 
ATOM   2794 H  HG23 . THR A 1 181 ? 147.616 175.909 150.302 1.00 64.61  ? 192 THR A HG23 1 
ATOM   2795 N  N    . ALA A 1 182 ? 147.629 177.344 153.170 1.00 78.32  ? 193 ALA A N    1 
ATOM   2796 C  CA   . ALA A 1 182 ? 146.497 178.252 153.307 1.00 78.25  ? 193 ALA A CA   1 
ATOM   2797 C  C    . ALA A 1 182 ? 145.904 178.601 151.947 1.00 79.46  ? 193 ALA A C    1 
ATOM   2798 O  O    . ALA A 1 182 ? 144.702 178.427 151.722 1.00 80.10  ? 193 ALA A O    1 
ATOM   2799 C  CB   . ALA A 1 182 ? 146.931 179.520 154.045 1.00 77.93  ? 193 ALA A CB   1 
ATOM   2800 H  H    . ALA A 1 182 ? 148.397 177.731 153.158 1.00 77.05  ? 193 ALA A H    1 
ATOM   2801 H  HA   . ALA A 1 182 ? 145.809 177.821 153.834 1.00 76.72  ? 193 ALA A HA   1 
ATOM   2802 H  HB1  . ALA A 1 182 ? 146.168 180.112 154.130 1.00 77.44  ? 193 ALA A HB1  1 
ATOM   2803 H  HB2  . ALA A 1 182 ? 147.260 179.275 154.924 1.00 77.13  ? 193 ALA A HB2  1 
ATOM   2804 H  HB3  . ALA A 1 182 ? 147.634 179.955 153.538 1.00 77.28  ? 193 ALA A HB3  1 
ATOM   2805 N  N    . THR A 1 183 ? 146.735 179.096 151.032 1.00 75.99  ? 194 THR A N    1 
ATOM   2806 C  CA   . THR A 1 183 ? 146.317 179.420 149.677 1.00 73.41  ? 194 THR A CA   1 
ATOM   2807 C  C    . THR A 1 183 ? 147.341 178.852 148.708 1.00 73.01  ? 194 THR A C    1 
ATOM   2808 O  O    . THR A 1 183 ? 148.548 178.958 148.942 1.00 75.13  ? 194 THR A O    1 
ATOM   2809 C  CB   . THR A 1 183 ? 146.184 180.936 149.474 1.00 74.35  ? 194 THR A CB   1 
ATOM   2810 O  OG1  . THR A 1 183 ? 145.345 181.488 150.496 1.00 78.02  ? 194 THR A OG1  1 
ATOM   2811 C  CG2  . THR A 1 183 ? 145.588 181.244 148.108 1.00 72.37  ? 194 THR A CG2  1 
ATOM   2812 H  H    . THR A 1 183 ? 147.567 179.255 151.180 1.00 74.28  ? 194 THR A H    1 
ATOM   2813 H  HA   . THR A 1 183 ? 145.458 179.011 149.493 1.00 74.12  ? 194 THR A HA   1 
ATOM   2814 H  HB   . THR A 1 183 ? 147.062 181.345 149.523 1.00 74.52  ? 194 THR A HB   1 
ATOM   2815 H  HG1  . THR A 1 183 ? 145.689 181.357 151.252 1.00 74.96  ? 194 THR A HG1  1 
ATOM   2816 H  HG21 . THR A 1 183 ? 145.416 182.196 148.031 1.00 74.29  ? 194 THR A HG21 1 
ATOM   2817 H  HG22 . THR A 1 183 ? 146.203 180.978 147.408 1.00 74.82  ? 194 THR A HG22 1 
ATOM   2818 H  HG23 . THR A 1 183 ? 144.753 180.764 147.995 1.00 73.61  ? 194 THR A HG23 1 
ATOM   2819 N  N    . ALA A 1 184 ? 146.858 178.254 147.621 1.00 72.94  ? 195 ALA A N    1 
ATOM   2820 C  CA   . ALA A 1 184 ? 147.731 177.591 146.656 1.00 71.78  ? 195 ALA A CA   1 
ATOM   2821 C  C    . ALA A 1 184 ? 147.200 177.831 145.250 1.00 70.48  ? 195 ALA A C    1 
ATOM   2822 O  O    . ALA A 1 184 ? 146.135 177.322 144.889 1.00 70.26  ? 195 ALA A O    1 
ATOM   2823 C  CB   . ALA A 1 184 ? 147.834 176.095 146.945 1.00 71.62  ? 195 ALA A CB   1 
ATOM   2824 H  H    . ALA A 1 184 ? 146.023 178.218 147.419 1.00 72.16  ? 195 ALA A H    1 
ATOM   2825 H  HA   . ALA A 1 184 ? 148.621 177.973 146.712 1.00 71.42  ? 195 ALA A HA   1 
ATOM   2826 H  HB1  . ALA A 1 184 ? 146.944 175.711 146.947 1.00 70.92  ? 195 ALA A HB1  1 
ATOM   2827 H  HB2  . ALA A 1 184 ? 148.374 175.677 146.256 1.00 70.86  ? 195 ALA A HB2  1 
ATOM   2828 H  HB3  . ALA A 1 184 ? 148.250 175.973 147.811 1.00 70.70  ? 195 ALA A HB3  1 
ATOM   2829 N  N    . THR A 1 185 ? 147.945 178.602 144.466 1.00 65.04  ? 196 THR A N    1 
ATOM   2830 C  CA   . THR A 1 185 ? 147.676 178.715 143.045 1.00 70.10  ? 196 THR A CA   1 
ATOM   2831 C  C    . THR A 1 185 ? 147.958 177.370 142.373 1.00 66.81  ? 196 THR A C    1 
ATOM   2832 O  O    . THR A 1 185 ? 148.789 176.594 142.853 1.00 71.18  ? 196 THR A O    1 
ATOM   2833 C  CB   . THR A 1 185 ? 148.555 179.808 142.435 1.00 74.28  ? 196 THR A CB   1 
ATOM   2834 O  OG1  . THR A 1 185 ? 148.386 181.025 143.173 1.00 71.85  ? 196 THR A OG1  1 
ATOM   2835 C  CG2  . THR A 1 185 ? 148.209 180.066 140.974 1.00 68.67  ? 196 THR A CG2  1 
ATOM   2836 H  H    . THR A 1 185 ? 148.614 179.071 144.737 1.00 68.93  ? 196 THR A H    1 
ATOM   2837 H  HA   . THR A 1 185 ? 146.746 178.951 142.913 1.00 69.94  ? 196 THR A HA   1 
ATOM   2838 H  HB   . THR A 1 185 ? 149.484 179.534 142.480 1.00 70.42  ? 196 THR A HB   1 
ATOM   2839 H  HG1  . THR A 1 185 ? 148.873 181.628 142.849 1.00 69.94  ? 196 THR A HG1  1 
ATOM   2840 H  HG21 . THR A 1 185 ? 148.824 180.719 140.604 1.00 69.41  ? 196 THR A HG21 1 
ATOM   2841 H  HG22 . THR A 1 185 ? 148.277 179.249 140.459 1.00 69.40  ? 196 THR A HG22 1 
ATOM   2842 H  HG23 . THR A 1 185 ? 147.308 180.416 140.903 1.00 69.12  ? 196 THR A HG23 1 
ATOM   2843 N  N    . PRO A 1 186 ? 147.273 177.057 141.268 1.00 62.03  ? 197 PRO A N    1 
ATOM   2844 C  CA   . PRO A 1 186 ? 147.602 175.811 140.556 1.00 66.94  ? 197 PRO A CA   1 
ATOM   2845 C  C    . PRO A 1 186 ? 149.084 175.676 140.258 1.00 73.20  ? 197 PRO A C    1 
ATOM   2846 O  O    . PRO A 1 186 ? 149.622 174.563 140.308 1.00 77.49  ? 197 PRO A O    1 
ATOM   2847 C  CB   . PRO A 1 186 ? 146.757 175.901 139.274 1.00 67.27  ? 197 PRO A CB   1 
ATOM   2848 C  CG   . PRO A 1 186 ? 146.125 177.278 139.285 1.00 70.97  ? 197 PRO A CG   1 
ATOM   2849 C  CD   . PRO A 1 186 ? 146.057 177.671 140.716 1.00 68.69  ? 197 PRO A CD   1 
ATOM   2850 H  HA   . PRO A 1 186 ? 147.311 175.044 141.074 1.00 69.24  ? 197 PRO A HA   1 
ATOM   2851 H  HB2  . PRO A 1 186 ? 147.330 175.797 138.498 1.00 69.69  ? 197 PRO A HB2  1 
ATOM   2852 H  HB3  . PRO A 1 186 ? 146.073 175.214 139.287 1.00 69.20  ? 197 PRO A HB3  1 
ATOM   2853 H  HG2  . PRO A 1 186 ? 146.682 177.897 138.787 1.00 69.91  ? 197 PRO A HG2  1 
ATOM   2854 H  HG3  . PRO A 1 186 ? 145.236 177.232 138.901 1.00 70.23  ? 197 PRO A HG3  1 
ATOM   2855 H  HD2  . PRO A 1 186 ? 146.074 178.631 140.804 1.00 69.63  ? 197 PRO A HD2  1 
ATOM   2856 H  HD3  . PRO A 1 186 ? 145.270 177.289 141.134 1.00 69.76  ? 197 PRO A HD3  1 
ATOM   2857 N  N    . GLN A 1 187 ? 149.768 176.783 139.960 1.00 75.25  ? 198 GLN A N    1 
ATOM   2858 C  CA   . GLN A 1 187 ? 151.223 176.737 139.870 1.00 74.49  ? 198 GLN A CA   1 
ATOM   2859 C  C    . GLN A 1 187 ? 151.828 176.302 141.198 1.00 70.47  ? 198 GLN A C    1 
ATOM   2860 O  O    . GLN A 1 187 ? 152.734 175.460 141.233 1.00 76.97  ? 198 GLN A O    1 
ATOM   2861 C  CB   . GLN A 1 187 ? 151.764 178.105 139.453 1.00 73.99  ? 198 GLN A CB   1 
ATOM   2862 C  CG   . GLN A 1 187 ? 153.246 178.116 139.106 1.00 75.66  ? 198 GLN A CG   1 
ATOM   2863 C  CD   . GLN A 1 187 ? 153.569 177.259 137.897 1.00 78.91  ? 198 GLN A CD   1 
ATOM   2864 O  OE1  . GLN A 1 187 ? 154.165 176.189 138.021 1.00 78.97  ? 198 GLN A OE1  1 
ATOM   2865 N  NE2  . GLN A 1 187 ? 153.176 177.727 136.717 1.00 79.41  ? 198 GLN A NE2  1 
ATOM   2866 H  H    . GLN A 1 187 ? 149.420 177.554 139.807 1.00 74.72  ? 198 GLN A H    1 
ATOM   2867 H  HA   . GLN A 1 187 ? 151.478 176.089 139.194 1.00 75.51  ? 198 GLN A HA   1 
ATOM   2868 H  HB2  . GLN A 1 187 ? 151.276 178.407 138.671 1.00 75.00  ? 198 GLN A HB2  1 
ATOM   2869 H  HB3  . GLN A 1 187 ? 151.629 178.729 140.184 1.00 75.01  ? 198 GLN A HB3  1 
ATOM   2870 H  HG2  . GLN A 1 187 ? 153.518 179.026 138.909 1.00 75.77  ? 198 GLN A HG2  1 
ATOM   2871 H  HG3  . GLN A 1 187 ? 153.752 177.774 139.859 1.00 75.52  ? 198 GLN A HG3  1 
ATOM   2872 H  HE21 . GLN A 1 187 ? 152.762 178.479 136.669 1.00 76.12  ? 198 GLN A HE21 1 
ATOM   2873 H  HE22 . GLN A 1 187 ? 153.336 177.277 136.001 1.00 75.78  ? 198 GLN A HE22 1 
ATOM   2874 N  N    . VAL A 1 188 ? 151.324 176.854 142.304 1.00 64.71  ? 199 VAL A N    1 
ATOM   2875 C  CA   . VAL A 1 188 ? 151.796 176.448 143.624 1.00 71.60  ? 199 VAL A CA   1 
ATOM   2876 C  C    . VAL A 1 188 ? 151.449 174.989 143.883 1.00 67.15  ? 199 VAL A C    1 
ATOM   2877 O  O    . VAL A 1 188 ? 152.238 174.244 144.475 1.00 71.67  ? 199 VAL A O    1 
ATOM   2878 C  CB   . VAL A 1 188 ? 151.206 177.371 144.707 1.00 73.62  ? 199 VAL A CB   1 
ATOM   2879 C  CG1  . VAL A 1 188 ? 151.606 176.894 146.094 1.00 70.63  ? 199 VAL A CG1  1 
ATOM   2880 C  CG2  . VAL A 1 188 ? 151.654 178.807 144.482 1.00 75.11  ? 199 VAL A CG2  1 
ATOM   2881 H  H    . VAL A 1 188 ? 150.715 177.461 142.315 1.00 70.73  ? 199 VAL A H    1 
ATOM   2882 H  HA   . VAL A 1 188 ? 152.762 176.534 143.653 1.00 71.86  ? 199 VAL A HA   1 
ATOM   2883 H  HB   . VAL A 1 188 ? 150.239 177.346 144.651 1.00 71.28  ? 199 VAL A HB   1 
ATOM   2884 H  HG11 . VAL A 1 188 ? 151.390 177.588 146.736 1.00 71.28  ? 199 VAL A HG11 1 
ATOM   2885 H  HG12 . VAL A 1 188 ? 151.116 176.084 146.308 1.00 70.99  ? 199 VAL A HG12 1 
ATOM   2886 H  HG13 . VAL A 1 188 ? 152.559 176.718 146.105 1.00 71.23  ? 199 VAL A HG13 1 
ATOM   2887 H  HG21 . VAL A 1 188 ? 151.271 179.369 145.173 1.00 71.67  ? 199 VAL A HG21 1 
ATOM   2888 H  HG22 . VAL A 1 188 ? 152.621 178.846 144.521 1.00 72.20  ? 199 VAL A HG22 1 
ATOM   2889 H  HG23 . VAL A 1 188 ? 151.348 179.101 143.610 1.00 72.12  ? 199 VAL A HG23 1 
ATOM   2890 N  N    . GLN A 1 189 ? 150.261 174.560 143.457 1.00 62.91  ? 200 GLN A N    1 
ATOM   2891 C  CA   . GLN A 1 189 ? 149.873 173.166 143.639 1.00 66.72  ? 200 GLN A CA   1 
ATOM   2892 C  C    . GLN A 1 189 ? 150.856 172.233 142.941 1.00 68.99  ? 200 GLN A C    1 
ATOM   2893 O  O    . GLN A 1 189 ? 151.336 171.260 143.534 1.00 72.47  ? 200 GLN A O    1 
ATOM   2894 C  CB   . GLN A 1 189 ? 148.456 172.947 143.108 1.00 74.30  ? 200 GLN A CB   1 
ATOM   2895 C  CG   . GLN A 1 189 ? 147.366 173.580 143.966 1.00 80.44  ? 200 GLN A CG   1 
ATOM   2896 C  CD   . GLN A 1 189 ? 145.973 173.001 143.729 1.00 79.70  ? 200 GLN A CD   1 
ATOM   2897 O  OE1  . GLN A 1 189 ? 145.034 173.327 144.455 1.00 78.49  ? 200 GLN A OE1  1 
ATOM   2898 N  NE2  . GLN A 1 189 ? 145.825 172.168 142.701 1.00 75.06  ? 200 GLN A NE2  1 
ATOM   2899 H  H    . GLN A 1 189 ? 149.671 175.048 143.066 1.00 71.60  ? 200 GLN A H    1 
ATOM   2900 H  HA   . GLN A 1 189 ? 149.879 172.957 144.587 1.00 71.58  ? 200 GLN A HA   1 
ATOM   2901 H  HB2  . GLN A 1 189 ? 148.392 173.320 142.215 1.00 72.66  ? 200 GLN A HB2  1 
ATOM   2902 H  HB3  . GLN A 1 189 ? 148.294 171.991 143.079 1.00 72.65  ? 200 GLN A HB3  1 
ATOM   2903 H  HG2  . GLN A 1 189 ? 147.587 173.447 144.901 1.00 72.34  ? 200 GLN A HG2  1 
ATOM   2904 H  HG3  . GLN A 1 189 ? 147.328 174.528 143.769 1.00 73.91  ? 200 GLN A HG3  1 
ATOM   2905 H  HE21 . GLN A 1 189 ? 146.490 171.959 142.201 1.00 72.69  ? 200 GLN A HE21 1 
ATOM   2906 H  HE22 . GLN A 1 189 ? 145.051 171.829 142.538 1.00 72.20  ? 200 GLN A HE22 1 
ATOM   2907 N  N    . GLU A 1 190 ? 151.170 172.521 141.676 1.00 74.90  ? 201 GLU A N    1 
ATOM   2908 C  CA   . GLU A 1 190 ? 152.102 171.676 140.937 1.00 72.57  ? 201 GLU A CA   1 
ATOM   2909 C  C    . GLU A 1 190 ? 153.498 171.730 141.543 1.00 75.11  ? 201 GLU A C    1 
ATOM   2910 O  O    . GLU A 1 190 ? 154.193 170.709 141.606 1.00 77.60  ? 201 GLU A O    1 
ATOM   2911 C  CB   . GLU A 1 190 ? 152.142 172.090 139.466 1.00 74.39  ? 201 GLU A CB   1 
ATOM   2912 C  CG   . GLU A 1 190 ? 150.808 171.973 138.749 1.00 79.60  ? 201 GLU A CG   1 
ATOM   2913 C  CD   . GLU A 1 190 ? 150.223 170.577 138.830 1.00 78.45  ? 201 GLU A CD   1 
ATOM   2914 O  OE1  . GLU A 1 190 ? 151.002 169.614 138.988 1.00 76.12  ? 201 GLU A OE1  1 
ATOM   2915 O  OE2  . GLU A 1 190 ? 148.985 170.443 138.737 1.00 78.33  ? 201 GLU A OE2  1 
ATOM   2916 H  H    . GLU A 1 190 ? 150.861 173.189 141.231 1.00 75.95  ? 201 GLU A H    1 
ATOM   2917 H  HA   . GLU A 1 190 ? 151.798 170.757 140.985 1.00 74.98  ? 201 GLU A HA   1 
ATOM   2918 H  HB2  . GLU A 1 190 ? 152.428 173.015 139.410 1.00 75.49  ? 201 GLU A HB2  1 
ATOM   2919 H  HB3  . GLU A 1 190 ? 152.777 171.523 139.000 1.00 75.62  ? 201 GLU A HB3  1 
ATOM   2920 H  HG2  . GLU A 1 190 ? 150.175 172.587 139.150 1.00 76.36  ? 201 GLU A HG2  1 
ATOM   2921 H  HG3  . GLU A 1 190 ? 150.933 172.191 137.812 1.00 76.65  ? 201 GLU A HG3  1 
ATOM   2922 N  N    . ASP A 1 191 ? 153.936 172.912 141.983 1.00 72.07  ? 202 ASP A N    1 
ATOM   2923 C  CA   . ASP A 1 191 ? 155.248 173.008 142.613 1.00 70.17  ? 202 ASP A CA   1 
ATOM   2924 C  C    . ASP A 1 191 ? 155.311 172.153 143.871 1.00 71.53  ? 202 ASP A C    1 
ATOM   2925 O  O    . ASP A 1 191 ? 156.301 171.449 144.103 1.00 71.69  ? 202 ASP A O    1 
ATOM   2926 C  CB   . ASP A 1 191 ? 155.575 174.465 142.938 1.00 73.56  ? 202 ASP A CB   1 
ATOM   2927 C  CG   . ASP A 1 191 ? 156.158 175.212 141.755 1.00 72.39  ? 202 ASP A CG   1 
ATOM   2928 O  OD1  . ASP A 1 191 ? 156.952 174.611 141.001 1.00 76.89  ? 202 ASP A OD1  1 
ATOM   2929 O  OD2  . ASP A 1 191 ? 155.825 176.402 141.578 1.00 73.12  ? 202 ASP A OD2  1 
ATOM   2930 H  H    . ASP A 1 191 ? 153.504 173.654 141.929 1.00 72.99  ? 202 ASP A H    1 
ATOM   2931 H  HA   . ASP A 1 191 ? 155.919 172.678 141.995 1.00 72.23  ? 202 ASP A HA   1 
ATOM   2932 H  HB2  . ASP A 1 191 ? 154.763 174.920 143.211 1.00 72.58  ? 202 ASP A HB2  1 
ATOM   2933 H  HB3  . ASP A 1 191 ? 156.227 174.488 143.656 1.00 72.65  ? 202 ASP A HB3  1 
ATOM   2934 N  N    . VAL A 1 192 ? 154.261 172.194 144.693 1.00 60.12  ? 203 VAL A N    1 
ATOM   2935 C  CA   . VAL A 1 192 ? 154.229 171.369 145.896 1.00 55.88  ? 203 VAL A CA   1 
ATOM   2936 C  C    . VAL A 1 192 ? 154.231 169.893 145.528 1.00 56.27  ? 203 VAL A C    1 
ATOM   2937 O  O    . VAL A 1 192 ? 154.941 169.086 146.140 1.00 64.12  ? 203 VAL A O    1 
ATOM   2938 C  CB   . VAL A 1 192 ? 153.011 171.735 146.765 1.00 55.68  ? 203 VAL A CB   1 
ATOM   2939 C  CG1  . VAL A 1 192 ? 152.913 170.805 147.962 1.00 57.92  ? 203 VAL A CG1  1 
ATOM   2940 C  CG2  . VAL A 1 192 ? 153.109 173.178 147.237 1.00 56.87  ? 203 VAL A CG2  1 
ATOM   2941 H  H    . VAL A 1 192 ? 153.565 172.685 144.576 1.00 61.32  ? 203 VAL A H    1 
ATOM   2942 H  HA   . VAL A 1 192 ? 155.029 171.542 146.414 1.00 59.65  ? 203 VAL A HA   1 
ATOM   2943 H  HB   . VAL A 1 192 ? 152.202 171.640 146.239 1.00 59.35  ? 203 VAL A HB   1 
ATOM   2944 H  HG11 . VAL A 1 192 ? 152.251 171.157 148.576 1.00 58.93  ? 203 VAL A HG11 1 
ATOM   2945 H  HG12 . VAL A 1 192 ? 152.645 169.923 147.662 1.00 58.92  ? 203 VAL A HG12 1 
ATOM   2946 H  HG13 . VAL A 1 192 ? 153.778 170.761 148.399 1.00 59.33  ? 203 VAL A HG13 1 
ATOM   2947 H  HG21 . VAL A 1 192 ? 152.251 173.450 147.599 1.00 59.18  ? 203 VAL A HG21 1 
ATOM   2948 H  HG22 . VAL A 1 192 ? 153.790 173.236 147.926 1.00 59.78  ? 203 VAL A HG22 1 
ATOM   2949 H  HG23 . VAL A 1 192 ? 153.347 173.748 146.491 1.00 60.32  ? 203 VAL A HG23 1 
ATOM   2950 N  N    . PHE A 1 193 ? 153.439 169.513 144.524 1.00 55.29  ? 204 PHE A N    1 
ATOM   2951 C  CA   . PHE A 1 193 ? 153.331 168.103 144.172 1.00 58.81  ? 204 PHE A CA   1 
ATOM   2952 C  C    . PHE A 1 193 ? 154.639 167.562 143.609 1.00 57.35  ? 204 PHE A C    1 
ATOM   2953 O  O    . PHE A 1 193 ? 154.979 166.398 143.848 1.00 58.97  ? 204 PHE A O    1 
ATOM   2954 C  CB   . PHE A 1 193 ? 152.198 167.901 143.165 1.00 62.21  ? 204 PHE A CB   1 
ATOM   2955 C  CG   . PHE A 1 193 ? 150.824 168.008 143.768 1.00 61.47  ? 204 PHE A CG   1 
ATOM   2956 C  CD1  . PHE A 1 193 ? 150.498 167.306 144.914 1.00 58.65  ? 204 PHE A CD1  1 
ATOM   2957 C  CD2  . PHE A 1 193 ? 149.858 168.810 143.184 1.00 64.41  ? 204 PHE A CD2  1 
ATOM   2958 C  CE1  . PHE A 1 193 ? 149.241 167.406 145.469 1.00 57.56  ? 204 PHE A CE1  1 
ATOM   2959 C  CE2  . PHE A 1 193 ? 148.597 168.912 143.736 1.00 62.77  ? 204 PHE A CE2  1 
ATOM   2960 C  CZ   . PHE A 1 193 ? 148.289 168.208 144.880 1.00 60.03  ? 204 PHE A CZ   1 
ATOM   2961 H  H    . PHE A 1 193 ? 152.963 170.043 144.042 1.00 60.26  ? 204 PHE A H    1 
ATOM   2962 H  HA   . PHE A 1 193 ? 153.127 167.594 144.971 1.00 59.50  ? 204 PHE A HA   1 
ATOM   2963 H  HB2  . PHE A 1 193 ? 152.272 168.575 142.471 1.00 60.93  ? 204 PHE A HB2  1 
ATOM   2964 H  HB3  . PHE A 1 193 ? 152.282 167.017 142.774 1.00 60.05  ? 204 PHE A HB3  1 
ATOM   2965 H  HD1  . PHE A 1 193 ? 151.136 166.764 145.318 1.00 59.49  ? 204 PHE A HD1  1 
ATOM   2966 H  HD2  . PHE A 1 193 ? 150.062 169.287 142.413 1.00 60.98  ? 204 PHE A HD2  1 
ATOM   2967 H  HE1  . PHE A 1 193 ? 149.035 166.930 146.240 1.00 59.13  ? 204 PHE A HE1  1 
ATOM   2968 H  HE2  . PHE A 1 193 ? 147.956 169.454 143.336 1.00 60.12  ? 204 PHE A HE2  1 
ATOM   2969 H  HZ   . PHE A 1 193 ? 147.440 168.274 145.254 1.00 59.05  ? 204 PHE A HZ   1 
ATOM   2970 N  N    . ALA A 1 194 ? 155.379 168.380 142.864 1.00 55.97  ? 205 ALA A N    1 
ATOM   2971 C  CA   . ALA A 1 194 ? 156.618 167.928 142.245 1.00 55.80  ? 205 ALA A CA   1 
ATOM   2972 C  C    . ALA A 1 194 ? 157.820 168.034 143.172 1.00 55.35  ? 205 ALA A C    1 
ATOM   2973 O  O    . ALA A 1 194 ? 158.761 167.242 143.043 1.00 63.65  ? 205 ALA A O    1 
ATOM   2974 C  CB   . ALA A 1 194 ? 156.893 168.733 140.972 1.00 61.99  ? 205 ALA A CB   1 
ATOM   2975 H  H    . ALA A 1 194 ? 155.184 169.202 142.701 1.00 59.86  ? 205 ALA A H    1 
ATOM   2976 H  HA   . ALA A 1 194 ? 156.520 166.997 141.991 1.00 58.75  ? 205 ALA A HA   1 
ATOM   2977 H  HB1  . ALA A 1 194 ? 157.721 168.419 140.573 1.00 59.78  ? 205 ALA A HB1  1 
ATOM   2978 H  HB2  . ALA A 1 194 ? 156.158 168.605 140.352 1.00 59.31  ? 205 ALA A HB2  1 
ATOM   2979 H  HB3  . ALA A 1 194 ? 156.973 169.671 141.203 1.00 60.25  ? 205 ALA A HB3  1 
ATOM   2980 N  N    . ALA A 1 195 ? 157.817 168.988 144.102 1.00 44.71  ? 206 ALA A N    1 
ATOM   2981 C  CA   . ALA A 1 195 ? 158.963 169.205 144.976 1.00 55.08  ? 206 ALA A CA   1 
ATOM   2982 C  C    . ALA A 1 195 ? 158.943 168.279 146.186 1.00 55.44  ? 206 ALA A C    1 
ATOM   2983 O  O    . ALA A 1 195 ? 159.970 167.691 146.538 1.00 55.96  ? 206 ALA A O    1 
ATOM   2984 C  CB   . ALA A 1 195 ? 159.001 170.666 145.430 1.00 59.56  ? 206 ALA A CB   1 
ATOM   2985 H  H    . ALA A 1 195 ? 157.160 169.524 144.246 1.00 55.35  ? 206 ALA A H    1 
ATOM   2986 H  HA   . ALA A 1 195 ? 159.776 169.027 144.478 1.00 56.51  ? 206 ALA A HA   1 
ATOM   2987 H  HB1  . ALA A 1 195 ? 159.768 170.795 146.009 1.00 57.41  ? 206 ALA A HB1  1 
ATOM   2988 H  HB2  . ALA A 1 195 ? 159.075 171.237 144.649 1.00 56.90  ? 206 ALA A HB2  1 
ATOM   2989 H  HB3  . ALA A 1 195 ? 158.183 170.867 145.911 1.00 57.18  ? 206 ALA A HB3  1 
ATOM   2990 N  N    . LEU A 1 196 ? 157.785 168.138 146.831 1.00 54.56  ? 207 LEU A N    1 
ATOM   2991 C  CA   . LEU A 1 196 ? 157.665 167.264 147.991 1.00 48.61  ? 207 LEU A CA   1 
ATOM   2992 C  C    . LEU A 1 196 ? 157.743 165.789 147.632 1.00 47.64  ? 207 LEU A C    1 
ATOM   2993 O  O    . LEU A 1 196 ? 157.690 164.954 148.539 1.00 52.21  ? 207 LEU A O    1 
ATOM   2994 C  CB   . LEU A 1 196 ? 156.350 167.540 148.721 1.00 39.63  ? 207 LEU A CB   1 
ATOM   2995 C  CG   . LEU A 1 196 ? 156.414 168.575 149.843 1.00 50.84  ? 207 LEU A CG   1 
ATOM   2996 C  CD1  . LEU A 1 196 ? 156.865 169.921 149.302 1.00 53.15  ? 207 LEU A CD1  1 
ATOM   2997 C  CD2  . LEU A 1 196 ? 155.067 168.695 150.536 1.00 54.49  ? 207 LEU A CD2  1 
ATOM   2998 H  H    . LEU A 1 196 ? 157.056 168.539 146.614 1.00 53.32  ? 207 LEU A H    1 
ATOM   2999 H  HA   . LEU A 1 196 ? 158.391 167.459 148.604 1.00 51.62  ? 207 LEU A HA   1 
ATOM   3000 H  HB2  . LEU A 1 196 ? 155.698 167.852 148.075 1.00 50.90  ? 207 LEU A HB2  1 
ATOM   3001 H  HB3  . LEU A 1 196 ? 156.040 166.709 149.114 1.00 49.43  ? 207 LEU A HB3  1 
ATOM   3002 H  HG   . LEU A 1 196 ? 157.064 168.286 150.502 1.00 52.35  ? 207 LEU A HG   1 
ATOM   3003 H  HD11 . LEU A 1 196 ? 156.788 170.586 150.004 1.00 52.99  ? 207 LEU A HD11 1 
ATOM   3004 H  HD12 . LEU A 1 196 ? 157.788 169.850 149.013 1.00 52.66  ? 207 LEU A HD12 1 
ATOM   3005 H  HD13 . LEU A 1 196 ? 156.300 170.165 148.552 1.00 52.34  ? 207 LEU A HD13 1 
ATOM   3006 H  HD21 . LEU A 1 196 ? 155.127 169.371 151.230 1.00 51.98  ? 207 LEU A HD21 1 
ATOM   3007 H  HD22 . LEU A 1 196 ? 154.397 168.951 149.882 1.00 51.92  ? 207 LEU A HD22 1 
ATOM   3008 H  HD23 . LEU A 1 196 ? 154.836 167.838 150.927 1.00 51.83  ? 207 LEU A HD23 1 
ATOM   3009 N  N    . HIS A 1 197 ? 157.863 165.444 146.350 1.00 40.50  ? 208 HIS A N    1 
ATOM   3010 C  CA   . HIS A 1 197 ? 157.916 164.048 145.923 1.00 41.70  ? 208 HIS A CA   1 
ATOM   3011 C  C    . HIS A 1 197 ? 156.725 163.264 146.466 1.00 48.91  ? 208 HIS A C    1 
ATOM   3012 O  O    . HIS A 1 197 ? 156.849 162.114 146.891 1.00 50.41  ? 208 HIS A O    1 
ATOM   3013 C  CB   . HIS A 1 197 ? 159.232 163.394 146.345 1.00 27.30  ? 208 HIS A CB   1 
ATOM   3014 C  CG   . HIS A 1 197 ? 160.449 164.106 145.847 1.00 26.96  ? 208 HIS A CG   1 
ATOM   3015 N  ND1  . HIS A 1 197 ? 161.631 164.143 146.554 1.00 46.02  ? 208 HIS A ND1  1 
ATOM   3016 C  CD2  . HIS A 1 197 ? 160.671 164.801 144.708 1.00 36.64  ? 208 HIS A CD2  1 
ATOM   3017 C  CE1  . HIS A 1 197 ? 162.527 164.836 145.875 1.00 46.60  ? 208 HIS A CE1  1 
ATOM   3018 N  NE2  . HIS A 1 197 ? 161.969 165.247 144.751 1.00 43.79  ? 208 HIS A NE2  1 
ATOM   3019 H  H    . HIS A 1 197 ? 157.914 166.006 145.701 1.00 44.98  ? 208 HIS A H    1 
ATOM   3020 H  HA   . HIS A 1 197 ? 157.871 164.019 144.955 1.00 43.82  ? 208 HIS A HA   1 
ATOM   3021 H  HB2  . HIS A 1 197 ? 159.275 163.376 147.314 1.00 42.45  ? 208 HIS A HB2  1 
ATOM   3022 H  HB3  . HIS A 1 197 ? 159.256 162.488 145.999 1.00 41.81  ? 208 HIS A HB3  1 
ATOM   3023 H  HD2  . HIS A 1 197 ? 160.057 164.953 144.025 1.00 43.14  ? 208 HIS A HD2  1 
ATOM   3024 H  HE1  . HIS A 1 197 ? 163.401 165.005 146.143 1.00 43.45  ? 208 HIS A HE1  1 
ATOM   3025 H  HE2  . HIS A 1 197 ? 162.357 165.716 144.143 1.00 42.86  ? 208 HIS A HE2  1 
ATOM   3026 N  N    . LEU A 1 198 ? 155.554 163.895 146.450 1.00 43.51  ? 209 LEU A N    1 
ATOM   3027 C  CA   . LEU A 1 198 ? 154.350 163.226 146.909 1.00 27.87  ? 209 LEU A CA   1 
ATOM   3028 C  C    . LEU A 1 198 ? 153.977 162.098 145.953 1.00 32.22  ? 209 LEU A C    1 
ATOM   3029 O  O    . LEU A 1 198 ? 154.344 162.096 144.776 1.00 27.96  ? 209 LEU A O    1 
ATOM   3030 C  CB   . LEU A 1 198 ? 153.193 164.218 147.028 1.00 28.62  ? 209 LEU A CB   1 
ATOM   3031 C  CG   . LEU A 1 198 ? 153.354 165.301 148.096 1.00 42.15  ? 209 LEU A CG   1 
ATOM   3032 C  CD1  . LEU A 1 198 ? 152.370 166.434 147.869 1.00 40.96  ? 209 LEU A CD1  1 
ATOM   3033 C  CD2  . LEU A 1 198 ? 153.183 164.717 149.487 1.00 46.15  ? 209 LEU A CD2  1 
ATOM   3034 H  H    . LEU A 1 198 ? 155.435 164.703 146.181 1.00 43.09  ? 209 LEU A H    1 
ATOM   3035 H  HA   . LEU A 1 198 ? 154.511 162.841 147.785 1.00 39.54  ? 209 LEU A HA   1 
ATOM   3036 H  HB2  . LEU A 1 198 ? 153.086 164.666 146.175 1.00 39.90  ? 209 LEU A HB2  1 
ATOM   3037 H  HB3  . LEU A 1 198 ? 152.385 163.723 147.237 1.00 38.97  ? 209 LEU A HB3  1 
ATOM   3038 H  HG   . LEU A 1 198 ? 154.250 165.669 148.037 1.00 42.29  ? 209 LEU A HG   1 
ATOM   3039 H  HD11 . LEU A 1 198 ? 152.533 167.129 148.525 1.00 41.69  ? 209 LEU A HD11 1 
ATOM   3040 H  HD12 . LEU A 1 198 ? 152.498 166.787 146.975 1.00 42.74  ? 209 LEU A HD12 1 
ATOM   3041 H  HD13 . LEU A 1 198 ? 151.467 166.092 147.964 1.00 41.83  ? 209 LEU A HD13 1 
ATOM   3042 H  HD21 . LEU A 1 198 ? 153.226 165.436 150.136 1.00 41.67  ? 209 LEU A HD21 1 
ATOM   3043 H  HD22 . LEU A 1 198 ? 152.322 164.275 149.539 1.00 41.88  ? 209 LEU A HD22 1 
ATOM   3044 H  HD23 . LEU A 1 198 ? 153.894 164.079 149.651 1.00 43.28  ? 209 LEU A HD23 1 
ATOM   3045 N  N    . LYS A 1 199 ? 153.241 161.126 146.481 1.00 43.23  ? 210 LYS A N    1 
ATOM   3046 C  CA   . LYS A 1 199 ? 152.839 159.978 145.683 1.00 48.08  ? 210 LYS A CA   1 
ATOM   3047 C  C    . LYS A 1 199 ? 151.995 160.432 144.498 1.00 35.70  ? 210 LYS A C    1 
ATOM   3048 O  O    . LYS A 1 199 ? 151.385 161.503 144.515 1.00 40.44  ? 210 LYS A O    1 
ATOM   3049 C  CB   . LYS A 1 199 ? 152.054 158.984 146.538 1.00 55.28  ? 210 LYS A CB   1 
ATOM   3050 C  CG   . LYS A 1 199 ? 152.869 158.332 147.639 1.00 50.80  ? 210 LYS A CG   1 
ATOM   3051 C  CD   . LYS A 1 199 ? 153.677 157.155 147.118 1.00 43.12  ? 210 LYS A CD   1 
ATOM   3052 C  CE   . LYS A 1 199 ? 154.498 156.515 148.226 1.00 49.35  ? 210 LYS A CE   1 
ATOM   3053 N  NZ   . LYS A 1 199 ? 155.865 157.098 148.323 1.00 47.00  ? 210 LYS A NZ   1 
ATOM   3054 H  H    . LYS A 1 199 ? 152.964 161.108 147.295 1.00 45.51  ? 210 LYS A H    1 
ATOM   3055 H  HA   . LYS A 1 199 ? 153.629 159.531 145.342 1.00 45.88  ? 210 LYS A HA   1 
ATOM   3056 H  HB2  . LYS A 1 199 ? 151.310 159.448 146.954 1.00 47.49  ? 210 LYS A HB2  1 
ATOM   3057 H  HB3  . LYS A 1 199 ? 151.722 158.276 145.966 1.00 47.36  ? 210 LYS A HB3  1 
ATOM   3058 H  HG2  . LYS A 1 199 ? 153.488 158.985 147.999 1.00 46.54  ? 210 LYS A HG2  1 
ATOM   3059 H  HG3  . LYS A 1 199 ? 152.274 158.012 148.335 1.00 47.00  ? 210 LYS A HG3  1 
ATOM   3060 H  HD2  . LYS A 1 199 ? 153.073 156.486 146.761 1.00 45.38  ? 210 LYS A HD2  1 
ATOM   3061 H  HD3  . LYS A 1 199 ? 154.285 157.464 146.428 1.00 45.07  ? 210 LYS A HD3  1 
ATOM   3062 H  HE2  . LYS A 1 199 ? 154.049 156.651 149.075 1.00 45.95  ? 210 LYS A HE2  1 
ATOM   3063 H  HE3  . LYS A 1 199 ? 154.588 155.566 148.046 1.00 47.22  ? 210 LYS A HE3  1 
ATOM   3064 H  HZ1  . LYS A 1 199 ? 156.334 156.896 147.594 1.00 46.77  ? 210 LYS A HZ1  1 
ATOM   3065 H  HZ2  . LYS A 1 199 ? 155.813 157.983 148.398 1.00 46.51  ? 210 LYS A HZ2  1 
ATOM   3066 H  HZ3  . LYS A 1 199 ? 156.284 156.771 149.036 1.00 45.93  ? 210 LYS A HZ3  1 
ATOM   3067 N  N    . LYS A 1 200 ? 151.974 159.607 143.454 1.00 29.73  ? 211 LYS A N    1 
ATOM   3068 C  CA   . LYS A 1 200 ? 151.213 159.959 142.258 1.00 40.84  ? 211 LYS A CA   1 
ATOM   3069 C  C    . LYS A 1 200 ? 149.749 160.232 142.571 1.00 42.79  ? 211 LYS A C    1 
ATOM   3070 O  O    . LYS A 1 200 ? 149.226 161.265 142.119 1.00 49.62  ? 211 LYS A O    1 
ATOM   3071 C  CB   . LYS A 1 200 ? 151.371 158.852 141.209 1.00 44.41  ? 211 LYS A CB   1 
ATOM   3072 C  CG   . LYS A 1 200 ? 150.302 158.834 140.118 1.00 48.82  ? 211 LYS A CG   1 
ATOM   3073 C  CD   . LYS A 1 200 ? 150.289 160.124 139.308 1.00 47.05  ? 211 LYS A CD   1 
ATOM   3074 C  CE   . LYS A 1 200 ? 148.931 160.368 138.668 1.00 45.40  ? 211 LYS A CE   1 
ATOM   3075 N  NZ   . LYS A 1 200 ? 147.889 160.722 139.672 1.00 42.51  ? 211 LYS A NZ   1 
ATOM   3076 H  H    . LYS A 1 200 ? 152.384 158.852 143.412 1.00 43.15  ? 211 LYS A H    1 
ATOM   3077 H  HA   . LYS A 1 200 ? 151.587 160.773 141.885 1.00 44.03  ? 211 LYS A HA   1 
ATOM   3078 H  HB2  . LYS A 1 200 ? 152.229 158.967 140.772 1.00 43.63  ? 211 LYS A HB2  1 
ATOM   3079 H  HB3  . LYS A 1 200 ? 151.351 157.992 141.657 1.00 43.27  ? 211 LYS A HB3  1 
ATOM   3080 H  HG2  . LYS A 1 200 ? 150.494 158.105 139.508 1.00 44.45  ? 211 LYS A HG2  1 
ATOM   3081 H  HG3  . LYS A 1 200 ? 149.425 158.706 140.513 1.00 44.80  ? 211 LYS A HG3  1 
ATOM   3082 H  HD2  . LYS A 1 200 ? 150.488 160.876 139.886 1.00 44.07  ? 211 LYS A HD2  1 
ATOM   3083 H  HD3  . LYS A 1 200 ? 150.950 160.062 138.601 1.00 43.98  ? 211 LYS A HD3  1 
ATOM   3084 H  HE2  . LYS A 1 200 ? 149.005 161.102 138.039 1.00 43.91  ? 211 LYS A HE2  1 
ATOM   3085 H  HE3  . LYS A 1 200 ? 148.647 159.562 138.210 1.00 43.53  ? 211 LYS A HE3  1 
ATOM   3086 H  HZ1  . LYS A 1 200 ? 147.760 160.041 140.231 1.00 44.12  ? 211 LYS A HZ1  1 
ATOM   3087 H  HZ2  . LYS A 1 200 ? 147.122 160.908 139.261 1.00 42.83  ? 211 LYS A HZ2  1 
ATOM   3088 H  HZ3  . LYS A 1 200 ? 148.147 161.434 140.139 1.00 43.04  ? 211 LYS A HZ3  1 
ATOM   3089 N  N    . PRO A 1 201 ? 149.037 159.383 143.316 1.00 38.49  ? 212 PRO A N    1 
ATOM   3090 C  CA   . PRO A 1 201 ? 147.641 159.692 143.660 1.00 32.42  ? 212 PRO A CA   1 
ATOM   3091 C  C    . PRO A 1 201 ? 147.577 160.586 144.888 1.00 36.20  ? 212 PRO A C    1 
ATOM   3092 O  O    . PRO A 1 201 ? 148.058 160.221 145.963 1.00 53.22  ? 212 PRO A O    1 
ATOM   3093 C  CB   . PRO A 1 201 ? 147.034 158.312 143.933 1.00 39.31  ? 212 PRO A CB   1 
ATOM   3094 C  CG   . PRO A 1 201 ? 148.182 157.496 144.432 1.00 45.86  ? 212 PRO A CG   1 
ATOM   3095 C  CD   . PRO A 1 201 ? 149.447 158.062 143.822 1.00 41.57  ? 212 PRO A CD   1 
ATOM   3096 H  HA   . PRO A 1 201 ? 147.184 160.113 142.916 1.00 41.42  ? 212 PRO A HA   1 
ATOM   3097 H  HB2  . PRO A 1 201 ? 146.343 158.385 144.609 1.00 41.32  ? 212 PRO A HB2  1 
ATOM   3098 H  HB3  . PRO A 1 201 ? 146.677 157.941 143.111 1.00 42.62  ? 212 PRO A HB3  1 
ATOM   3099 H  HG2  . PRO A 1 201 ? 148.220 157.557 145.400 1.00 42.59  ? 212 PRO A HG2  1 
ATOM   3100 H  HG3  . PRO A 1 201 ? 148.062 156.573 144.159 1.00 43.38  ? 212 PRO A HG3  1 
ATOM   3101 H  HD2  . PRO A 1 201 ? 150.131 158.157 144.501 1.00 42.34  ? 212 PRO A HD2  1 
ATOM   3102 H  HD3  . PRO A 1 201 ? 149.747 157.497 143.093 1.00 42.26  ? 212 PRO A HD3  1 
ATOM   3103 N  N    . VAL A 1 202 ? 146.986 161.766 144.725 1.00 41.03  ? 213 VAL A N    1 
ATOM   3104 C  CA   . VAL A 1 202 ? 146.798 162.706 145.820 1.00 40.91  ? 213 VAL A CA   1 
ATOM   3105 C  C    . VAL A 1 202 ? 145.435 163.360 145.664 1.00 54.95  ? 213 VAL A C    1 
ATOM   3106 O  O    . VAL A 1 202 ? 144.973 163.622 144.549 1.00 64.65  ? 213 VAL A O    1 
ATOM   3107 C  CB   . VAL A 1 202 ? 147.903 163.783 145.865 1.00 36.25  ? 213 VAL A CB   1 
ATOM   3108 C  CG1  . VAL A 1 202 ? 147.633 164.769 146.991 1.00 47.50  ? 213 VAL A CG1  1 
ATOM   3109 C  CG2  . VAL A 1 202 ? 149.264 163.136 146.022 1.00 46.10  ? 213 VAL A CG2  1 
ATOM   3110 H  H    . VAL A 1 202 ? 146.681 162.049 143.972 1.00 46.37  ? 213 VAL A H    1 
ATOM   3111 H  HA   . VAL A 1 202 ? 146.809 162.225 146.662 1.00 45.16  ? 213 VAL A HA   1 
ATOM   3112 H  HB   . VAL A 1 202 ? 147.899 164.274 145.028 1.00 45.76  ? 213 VAL A HB   1 
ATOM   3113 H  HG11 . VAL A 1 202 ? 148.457 165.231 147.213 1.00 47.48  ? 213 VAL A HG11 1 
ATOM   3114 H  HG12 . VAL A 1 202 ? 146.963 165.407 146.701 1.00 48.47  ? 213 VAL A HG12 1 
ATOM   3115 H  HG13 . VAL A 1 202 ? 147.314 164.281 147.766 1.00 47.96  ? 213 VAL A HG13 1 
ATOM   3116 H  HG21 . VAL A 1 202 ? 149.927 163.824 146.193 1.00 47.00  ? 213 VAL A HG21 1 
ATOM   3117 H  HG22 . VAL A 1 202 ? 149.232 162.513 146.763 1.00 46.59  ? 213 VAL A HG22 1 
ATOM   3118 H  HG23 . VAL A 1 202 ? 149.477 162.665 145.203 1.00 47.18  ? 213 VAL A HG23 1 
ATOM   3119 N  N    . ALA A 1 203 ? 144.791 163.622 146.795 1.00 40.38  ? 214 ALA A N    1 
ATOM   3120 C  CA   . ALA A 1 203 ? 143.523 164.334 146.828 1.00 40.82  ? 214 ALA A CA   1 
ATOM   3121 C  C    . ALA A 1 203 ? 143.785 165.765 147.279 1.00 36.55  ? 214 ALA A C    1 
ATOM   3122 O  O    . ALA A 1 203 ? 144.314 165.990 148.372 1.00 45.42  ? 214 ALA A O    1 
ATOM   3123 C  CB   . ALA A 1 203 ? 142.535 163.634 147.756 1.00 45.27  ? 214 ALA A CB   1 
ATOM   3124 H  H    . ALA A 1 203 ? 145.076 163.392 147.573 1.00 43.67  ? 214 ALA A H    1 
ATOM   3125 H  HA   . ALA A 1 203 ? 143.140 164.359 145.937 1.00 44.15  ? 214 ALA A HA   1 
ATOM   3126 H  HB1  . ALA A 1 203 ? 141.788 164.228 147.924 1.00 44.28  ? 214 ALA A HB1  1 
ATOM   3127 H  HB2  . ALA A 1 203 ? 142.223 162.819 147.331 1.00 44.21  ? 214 ALA A HB2  1 
ATOM   3128 H  HB3  . ALA A 1 203 ? 142.990 163.424 148.584 1.00 43.54  ? 214 ALA A HB3  1 
ATOM   3129 N  N    . ILE A 1 204 ? 143.414 166.727 146.433 1.00 49.41  ? 215 ILE A N    1 
ATOM   3130 C  CA   . ILE A 1 204 ? 143.794 168.116 146.671 1.00 61.59  ? 215 ILE A CA   1 
ATOM   3131 C  C    . ILE A 1 204 ? 143.101 168.662 147.914 1.00 66.39  ? 215 ILE A C    1 
ATOM   3132 O  O    . ILE A 1 204 ? 143.675 169.474 148.649 1.00 64.77  ? 215 ILE A O    1 
ATOM   3133 C  CB   . ILE A 1 204 ? 143.487 168.966 145.425 1.00 64.92  ? 215 ILE A CB   1 
ATOM   3134 C  CG1  . ILE A 1 204 ? 144.374 168.527 144.256 1.00 61.97  ? 215 ILE A CG1  1 
ATOM   3135 C  CG2  . ILE A 1 204 ? 143.687 170.444 145.725 1.00 66.71  ? 215 ILE A CG2  1 
ATOM   3136 C  CD1  . ILE A 1 204 ? 143.750 167.465 143.375 1.00 65.03  ? 215 ILE A CD1  1 
ATOM   3137 H  H    . ILE A 1 204 ? 142.944 166.602 145.725 1.00 59.22  ? 215 ILE A H    1 
ATOM   3138 H  HA   . ILE A 1 204 ? 144.750 168.155 146.827 1.00 59.98  ? 215 ILE A HA   1 
ATOM   3139 H  HB   . ILE A 1 204 ? 142.559 168.825 145.178 1.00 61.46  ? 215 ILE A HB   1 
ATOM   3140 H  HG12 . ILE A 1 204 ? 144.565 169.297 143.698 1.00 61.74  ? 215 ILE A HG12 1 
ATOM   3141 H  HG13 . ILE A 1 204 ? 145.202 168.167 144.610 1.00 60.05  ? 215 ILE A HG13 1 
ATOM   3142 H  HG21 . ILE A 1 204 ? 143.719 170.937 144.891 1.00 62.56  ? 215 ILE A HG21 1 
ATOM   3143 H  HG22 . ILE A 1 204 ? 142.944 170.760 146.263 1.00 62.53  ? 215 ILE A HG22 1 
ATOM   3144 H  HG23 . ILE A 1 204 ? 144.520 170.559 146.208 1.00 61.20  ? 215 ILE A HG23 1 
ATOM   3145 H  HD11 . ILE A 1 204 ? 144.261 167.399 142.553 1.00 61.68  ? 215 ILE A HD11 1 
ATOM   3146 H  HD12 . ILE A 1 204 ? 143.767 166.614 143.840 1.00 60.92  ? 215 ILE A HD12 1 
ATOM   3147 H  HD13 . ILE A 1 204 ? 142.835 167.717 143.175 1.00 62.00  ? 215 ILE A HD13 1 
ATOM   3148 N  N    . PHE A 1 205 ? 141.863 168.244 148.158 1.00 57.27  ? 216 PHE A N    1 
ATOM   3149 C  CA   . PHE A 1 205 ? 141.082 168.660 149.325 1.00 50.06  ? 216 PHE A CA   1 
ATOM   3150 C  C    . PHE A 1 205 ? 141.278 170.144 149.634 1.00 52.02  ? 216 PHE A C    1 
ATOM   3151 O  O    . PHE A 1 205 ? 141.678 170.534 150.730 1.00 58.03  ? 216 PHE A O    1 
ATOM   3152 C  CB   . PHE A 1 205 ? 141.425 167.817 150.552 1.00 46.47  ? 216 PHE A CB   1 
ATOM   3153 C  CG   . PHE A 1 205 ? 141.045 166.370 150.433 1.00 47.20  ? 216 PHE A CG   1 
ATOM   3154 C  CD1  . PHE A 1 205 ? 139.789 165.999 149.986 1.00 59.24  ? 216 PHE A CD1  1 
ATOM   3155 C  CD2  . PHE A 1 205 ? 141.935 165.380 150.801 1.00 51.80  ? 216 PHE A CD2  1 
ATOM   3156 C  CE1  . PHE A 1 205 ? 139.438 164.667 149.889 1.00 57.92  ? 216 PHE A CE1  1 
ATOM   3157 C  CE2  . PHE A 1 205 ? 141.589 164.050 150.710 1.00 55.57  ? 216 PHE A CE2  1 
ATOM   3158 C  CZ   . PHE A 1 205 ? 140.340 163.692 150.253 1.00 54.73  ? 216 PHE A CZ   1 
ATOM   3159 H  H    . PHE A 1 205 ? 141.438 167.700 147.645 1.00 55.70  ? 216 PHE A H    1 
ATOM   3160 H  HA   . PHE A 1 205 ? 140.143 168.530 149.127 1.00 55.68  ? 216 PHE A HA   1 
ATOM   3161 H  HB2  . PHE A 1 205 ? 142.380 167.860 150.706 1.00 55.00  ? 216 PHE A HB2  1 
ATOM   3162 H  HB3  . PHE A 1 205 ? 140.955 168.181 151.318 1.00 55.43  ? 216 PHE A HB3  1 
ATOM   3163 H  HD1  . PHE A 1 205 ? 139.178 166.654 149.738 1.00 57.84  ? 216 PHE A HD1  1 
ATOM   3164 H  HD2  . PHE A 1 205 ? 142.780 165.615 151.109 1.00 55.37  ? 216 PHE A HD2  1 
ATOM   3165 H  HE1  . PHE A 1 205 ? 138.594 164.429 149.581 1.00 57.19  ? 216 PHE A HE1  1 
ATOM   3166 H  HE2  . PHE A 1 205 ? 142.202 163.394 150.954 1.00 56.21  ? 216 PHE A HE2  1 
ATOM   3167 H  HZ   . PHE A 1 205 ? 140.107 162.794 150.189 1.00 56.36  ? 216 PHE A HZ   1 
ATOM   3168 N  N    . LYS A 1 206 ? 140.987 170.975 148.639 1.00 55.26  ? 217 LYS A N    1 
ATOM   3169 C  CA   . LYS A 1 206 ? 141.010 172.423 148.802 1.00 62.05  ? 217 LYS A CA   1 
ATOM   3170 C  C    . LYS A 1 206 ? 139.582 172.944 148.875 1.00 72.01  ? 217 LYS A C    1 
ATOM   3171 O  O    . LYS A 1 206 ? 138.744 172.592 148.038 1.00 77.79  ? 217 LYS A O    1 
ATOM   3172 C  CB   . LYS A 1 206 ? 141.766 173.098 147.657 1.00 61.04  ? 217 LYS A CB   1 
ATOM   3173 C  CG   . LYS A 1 206 ? 140.966 173.250 146.376 1.00 67.55  ? 217 LYS A CG   1 
ATOM   3174 C  CD   . LYS A 1 206 ? 141.855 173.602 145.190 1.00 60.07  ? 217 LYS A CD   1 
ATOM   3175 C  CE   . LYS A 1 206 ? 142.630 174.894 145.417 1.00 61.08  ? 217 LYS A CE   1 
ATOM   3176 N  NZ   . LYS A 1 206 ? 141.729 176.075 145.530 1.00 62.11  ? 217 LYS A NZ   1 
ATOM   3177 H  H    . LYS A 1 206 ? 140.768 170.720 147.848 1.00 63.10  ? 217 LYS A H    1 
ATOM   3178 H  HA   . LYS A 1 206 ? 141.458 172.648 149.633 1.00 64.59  ? 217 LYS A HA   1 
ATOM   3179 H  HB2  . LYS A 1 206 ? 142.017 173.988 147.947 1.00 63.73  ? 217 LYS A HB2  1 
ATOM   3180 H  HB3  . LYS A 1 206 ? 142.561 172.582 147.456 1.00 64.28  ? 217 LYS A HB3  1 
ATOM   3181 H  HG2  . LYS A 1 206 ? 140.517 172.413 146.179 1.00 65.23  ? 217 LYS A HG2  1 
ATOM   3182 H  HG3  . LYS A 1 206 ? 140.315 173.961 146.486 1.00 65.65  ? 217 LYS A HG3  1 
ATOM   3183 H  HD2  . LYS A 1 206 ? 142.494 172.887 145.049 1.00 64.63  ? 217 LYS A HD2  1 
ATOM   3184 H  HD3  . LYS A 1 206 ? 141.302 173.716 144.401 1.00 63.74  ? 217 LYS A HD3  1 
ATOM   3185 H  HE2  . LYS A 1 206 ? 143.151 174.827 146.232 1.00 64.51  ? 217 LYS A HE2  1 
ATOM   3186 H  HE3  . LYS A 1 206 ? 143.219 175.042 144.661 1.00 64.87  ? 217 LYS A HE3  1 
ATOM   3187 H  HZ1  . LYS A 1 206 ? 141.122 175.935 146.166 1.00 63.91  ? 217 LYS A HZ1  1 
ATOM   3188 H  HZ2  . LYS A 1 206 ? 142.202 176.799 145.737 1.00 64.32  ? 217 LYS A HZ2  1 
ATOM   3189 H  HZ3  . LYS A 1 206 ? 141.310 176.213 144.757 1.00 64.85  ? 217 LYS A HZ3  1 
ATOM   3190 N  N    . THR A 1 207 ? 139.306 173.769 149.877 1.00 70.00  ? 218 THR A N    1 
ATOM   3191 C  CA   . THR A 1 207 ? 137.961 174.296 150.043 1.00 66.37  ? 218 THR A CA   1 
ATOM   3192 C  C    . THR A 1 207 ? 137.620 175.201 148.863 1.00 62.35  ? 218 THR A C    1 
ATOM   3193 O  O    . THR A 1 207 ? 138.414 176.088 148.521 1.00 60.22  ? 218 THR A O    1 
ATOM   3194 C  CB   . THR A 1 207 ? 137.837 175.065 151.359 1.00 69.12  ? 218 THR A CB   1 
ATOM   3195 O  OG1  . THR A 1 207 ? 136.468 175.426 151.579 1.00 72.38  ? 218 THR A OG1  1 
ATOM   3196 C  CG2  . THR A 1 207 ? 138.691 176.322 151.346 1.00 67.11  ? 218 THR A CG2  1 
ATOM   3197 H  H    . THR A 1 207 ? 139.873 174.037 150.466 1.00 67.38  ? 218 THR A H    1 
ATOM   3198 H  HA   . THR A 1 207 ? 137.335 173.562 150.071 1.00 67.34  ? 218 THR A HA   1 
ATOM   3199 H  HB   . THR A 1 207 ? 138.139 174.502 152.089 1.00 68.10  ? 218 THR A HB   1 
ATOM   3200 H  HG1  . THR A 1 207 ? 136.395 175.852 152.300 1.00 67.87  ? 218 THR A HG1  1 
ATOM   3201 H  HG21 . THR A 1 207 ? 138.716 176.698 152.237 1.00 67.61  ? 218 THR A HG21 1 
ATOM   3202 H  HG22 . THR A 1 207 ? 139.595 176.112 151.064 1.00 67.60  ? 218 THR A HG22 1 
ATOM   3203 H  HG23 . THR A 1 207 ? 138.314 176.980 150.742 1.00 67.39  ? 218 THR A HG23 1 
ATOM   3204 N  N    . PRO A 1 208 ? 136.480 175.002 148.202 1.00 67.17  ? 219 PRO A N    1 
ATOM   3205 C  CA   . PRO A 1 208 ? 136.113 175.908 147.105 1.00 68.99  ? 219 PRO A CA   1 
ATOM   3206 C  C    . PRO A 1 208 ? 136.071 177.347 147.591 1.00 69.37  ? 219 PRO A C    1 
ATOM   3207 O  O    . PRO A 1 208 ? 135.267 177.709 148.453 1.00 72.43  ? 219 PRO A O    1 
ATOM   3208 C  CB   . PRO A 1 208 ? 134.730 175.404 146.673 1.00 68.54  ? 219 PRO A CB   1 
ATOM   3209 C  CG   . PRO A 1 208 ? 134.665 173.998 147.140 1.00 70.39  ? 219 PRO A CG   1 
ATOM   3210 C  CD   . PRO A 1 208 ? 135.481 173.935 148.391 1.00 69.30  ? 219 PRO A CD   1 
ATOM   3211 H  HA   . PRO A 1 208 ? 136.737 175.826 146.368 1.00 68.38  ? 219 PRO A HA   1 
ATOM   3212 H  HB2  . PRO A 1 208 ? 134.040 175.938 147.096 1.00 69.12  ? 219 PRO A HB2  1 
ATOM   3213 H  HB3  . PRO A 1 208 ? 134.654 175.448 145.707 1.00 68.33  ? 219 PRO A HB3  1 
ATOM   3214 H  HG2  . PRO A 1 208 ? 133.743 173.760 147.321 1.00 69.78  ? 219 PRO A HG2  1 
ATOM   3215 H  HG3  . PRO A 1 208 ? 135.040 173.416 146.460 1.00 68.23  ? 219 PRO A HG3  1 
ATOM   3216 H  HD2  . PRO A 1 208 ? 134.928 174.122 149.166 1.00 69.02  ? 219 PRO A HD2  1 
ATOM   3217 H  HD3  . PRO A 1 208 ? 135.915 173.070 148.463 1.00 68.21  ? 219 PRO A HD3  1 
ATOM   3218 N  N    . CYS A 1 209 ? 136.956 178.171 147.028 1.00 61.11  ? 220 CYS A N    1 
ATOM   3219 C  CA   . CYS A 1 209 ? 136.999 179.577 147.410 1.00 66.60  ? 220 CYS A CA   1 
ATOM   3220 C  C    . CYS A 1 209 ? 135.658 180.259 147.179 1.00 71.75  ? 220 CYS A C    1 
ATOM   3221 O  O    . CYS A 1 209 ? 135.356 181.271 147.821 1.00 68.87  ? 220 CYS A O    1 
ATOM   3222 C  CB   . CYS A 1 209 ? 138.103 180.288 146.632 1.00 63.37  ? 220 CYS A CB   1 
ATOM   3223 S  SG   . CYS A 1 209 ? 137.836 180.349 144.847 1.00 64.86  ? 220 CYS A SG   1 
ATOM   3224 H  H    . CYS A 1 209 ? 137.534 177.942 146.434 1.00 65.09  ? 220 CYS A H    1 
ATOM   3225 H  HA   . CYS A 1 209 ? 137.209 179.642 148.355 1.00 66.57  ? 220 CYS A HA   1 
ATOM   3226 H  HB2  . CYS A 1 209 ? 138.180 181.199 146.954 1.00 66.44  ? 220 CYS A HB2  1 
ATOM   3227 H  HB3  . CYS A 1 209 ? 138.930 179.811 146.790 1.00 65.50  ? 220 CYS A HB3  1 
ATOM   3228 H  HG   . CYS A 1 209 ? 138.802 180.844 144.335 1.00 66.50  ? 220 CYS A HG   1 
ATOM   3229 N  N    . PHE A 1 210 ? 134.849 179.726 146.269 1.00 74.42  ? 221 PHE A N    1 
ATOM   3230 C  CA   . PHE A 1 210 ? 133.549 180.311 145.981 1.00 72.18  ? 221 PHE A CA   1 
ATOM   3231 C  C    . PHE A 1 210 ? 132.670 180.310 147.225 1.00 73.08  ? 221 PHE A C    1 
ATOM   3232 O  O    . PHE A 1 210 ? 132.591 179.310 147.945 1.00 68.44  ? 221 PHE A O    1 
ATOM   3233 C  CB   . PHE A 1 210 ? 132.873 179.529 144.857 1.00 70.65  ? 221 PHE A CB   1 
ATOM   3234 C  CG   . PHE A 1 210 ? 131.410 179.827 144.700 1.00 68.54  ? 221 PHE A CG   1 
ATOM   3235 C  CD1  . PHE A 1 210 ? 130.996 180.997 144.090 1.00 68.46  ? 221 PHE A CD1  1 
ATOM   3236 C  CD2  . PHE A 1 210 ? 130.451 178.935 145.151 1.00 69.32  ? 221 PHE A CD2  1 
ATOM   3237 C  CE1  . PHE A 1 210 ? 129.652 181.279 143.937 1.00 70.85  ? 221 PHE A CE1  1 
ATOM   3238 C  CE2  . PHE A 1 210 ? 129.104 179.212 145.001 1.00 72.79  ? 221 PHE A CE2  1 
ATOM   3239 C  CZ   . PHE A 1 210 ? 128.705 180.385 144.392 1.00 74.88  ? 221 PHE A CZ   1 
ATOM   3240 H  H    . PHE A 1 210 ? 135.030 179.025 145.805 1.00 71.54  ? 221 PHE A H    1 
ATOM   3241 H  HA   . PHE A 1 210 ? 133.665 181.229 145.688 1.00 71.33  ? 221 PHE A HA   1 
ATOM   3242 H  HB2  . PHE A 1 210 ? 133.317 179.743 144.026 1.00 71.36  ? 221 PHE A HB2  1 
ATOM   3243 H  HB3  . PHE A 1 210 ? 132.962 178.580 145.041 1.00 71.47  ? 221 PHE A HB3  1 
ATOM   3244 H  HD1  . PHE A 1 210 ? 131.631 181.601 143.781 1.00 70.92  ? 221 PHE A HD1  1 
ATOM   3245 H  HD2  . PHE A 1 210 ? 130.715 178.144 145.561 1.00 70.78  ? 221 PHE A HD2  1 
ATOM   3246 H  HE1  . PHE A 1 210 ? 129.387 182.070 143.526 1.00 71.12  ? 221 PHE A HE1  1 
ATOM   3247 H  HE2  . PHE A 1 210 ? 128.467 178.608 145.308 1.00 71.53  ? 221 PHE A HE2  1 
ATOM   3248 H  HZ   . PHE A 1 210 ? 127.800 180.573 144.290 1.00 72.22  ? 221 PHE A HZ   1 
ATOM   3249 N  N    . ARG A 1 211 ? 132.012 181.439 147.476 1.00 86.45  ? 222 ARG A N    1 
ATOM   3250 C  CA   . ARG A 1 211 ? 131.028 181.568 148.544 1.00 84.54  ? 222 ARG A CA   1 
ATOM   3251 C  C    . ARG A 1 211 ? 129.721 182.047 147.929 1.00 85.88  ? 222 ARG A C    1 
ATOM   3252 O  O    . ARG A 1 211 ? 129.690 183.089 147.266 1.00 85.42  ? 222 ARG A O    1 
ATOM   3253 C  CB   . ARG A 1 211 ? 131.510 182.538 149.625 1.00 81.93  ? 222 ARG A CB   1 
ATOM   3254 C  CG   . ARG A 1 211 ? 132.513 181.933 150.595 1.00 84.87  ? 222 ARG A CG   1 
ATOM   3255 C  CD   . ARG A 1 211 ? 132.989 182.953 151.619 1.00 88.53  ? 222 ARG A CD   1 
ATOM   3256 N  NE   . ARG A 1 211 ? 133.738 184.041 151.001 1.00 86.36  ? 222 ARG A NE   1 
ATOM   3257 C  CZ   . ARG A 1 211 ? 134.974 183.927 150.532 1.00 84.86  ? 222 ARG A CZ   1 
ATOM   3258 N  NH1  . ARG A 1 211 ? 135.636 182.783 150.596 1.00 85.14  ? 222 ARG A NH1  1 
ATOM   3259 N  NH2  . ARG A 1 211 ? 135.560 184.989 149.986 1.00 80.79  ? 222 ARG A NH2  1 
ATOM   3260 H  H    . ARG A 1 211 ? 132.123 182.164 147.027 1.00 83.87  ? 222 ARG A H    1 
ATOM   3261 H  HA   . ARG A 1 211 ? 130.875 180.702 148.954 1.00 83.79  ? 222 ARG A HA   1 
ATOM   3262 H  HB2  . ARG A 1 211 ? 131.934 183.297 149.195 1.00 83.66  ? 222 ARG A HB2  1 
ATOM   3263 H  HB3  . ARG A 1 211 ? 130.744 182.836 150.139 1.00 84.12  ? 222 ARG A HB3  1 
ATOM   3264 H  HG2  . ARG A 1 211 ? 132.094 181.199 151.071 1.00 84.27  ? 222 ARG A HG2  1 
ATOM   3265 H  HG3  . ARG A 1 211 ? 133.285 181.615 150.101 1.00 83.90  ? 222 ARG A HG3  1 
ATOM   3266 H  HD2  . ARG A 1 211 ? 132.219 183.334 152.069 1.00 84.66  ? 222 ARG A HD2  1 
ATOM   3267 H  HD3  . ARG A 1 211 ? 133.567 182.513 152.261 1.00 85.09  ? 222 ARG A HD3  1 
ATOM   3268 H  HE   . ARG A 1 211 ? 133.386 184.825 151.011 1.00 84.39  ? 222 ARG A HE   1 
ATOM   3269 H  HH11 . ARG A 1 211 ? 135.268 182.090 150.946 1.00 84.20  ? 222 ARG A HH11 1 
ATOM   3270 H  HH12 . ARG A 1 211 ? 136.436 182.733 150.285 1.00 84.16  ? 222 ARG A HH12 1 
ATOM   3271 H  HH21 . ARG A 1 211 ? 136.361 184.926 149.679 1.00 84.20  ? 222 ARG A HH21 1 
ATOM   3272 H  HH22 . ARG A 1 211 ? 135.139 185.737 149.940 1.00 83.49  ? 222 ARG A HH22 1 
ATOM   3273 N  N    . ALA A 1 212 ? 128.647 181.287 148.150 1.00 91.87  ? 223 ALA A N    1 
ATOM   3274 C  CA   . ALA A 1 212 ? 127.368 181.620 147.531 1.00 93.11  ? 223 ALA A CA   1 
ATOM   3275 C  C    . ALA A 1 212 ? 126.866 182.987 147.975 1.00 93.41  ? 223 ALA A C    1 
ATOM   3276 O  O    . ALA A 1 212 ? 126.114 183.639 147.242 1.00 95.60  ? 223 ALA A O    1 
ATOM   3277 C  CB   . ALA A 1 212 ? 126.332 180.545 147.857 1.00 93.05  ? 223 ALA A CB   1 
ATOM   3278 H  H    . ALA A 1 212 ? 128.633 180.584 148.646 1.00 91.68  ? 223 ALA A H    1 
ATOM   3279 H  HA   . ALA A 1 212 ? 127.482 181.644 146.568 1.00 91.75  ? 223 ALA A HA   1 
ATOM   3280 H  HB1  . ALA A 1 212 ? 125.491 180.780 147.434 1.00 92.51  ? 223 ALA A HB1  1 
ATOM   3281 H  HB2  . ALA A 1 212 ? 126.646 179.692 147.517 1.00 91.95  ? 223 ALA A HB2  1 
ATOM   3282 H  HB3  . ALA A 1 212 ? 126.218 180.497 148.819 1.00 92.25  ? 223 ALA A HB3  1 
ATOM   3283 N  N    . ASN A 1 213 ? 127.263 183.437 149.162 1.00 91.87  ? 224 ASN A N    1 
ATOM   3284 C  CA   . ASN A 1 213 ? 126.817 184.716 149.697 1.00 95.44  ? 224 ASN A CA   1 
ATOM   3285 C  C    . ASN A 1 213 ? 127.633 185.897 149.182 1.00 93.27  ? 224 ASN A C    1 
ATOM   3286 O  O    . ASN A 1 213 ? 127.570 186.978 149.778 1.00 92.95  ? 224 ASN A O    1 
ATOM   3287 C  CB   . ASN A 1 213 ? 126.864 184.684 151.228 1.00 93.92  ? 224 ASN A CB   1 
ATOM   3288 C  CG   . ASN A 1 213 ? 128.274 184.550 151.765 1.00 92.39  ? 224 ASN A CG   1 
ATOM   3289 O  OD1  . ASN A 1 213 ? 128.931 185.544 152.073 1.00 91.81  ? 224 ASN A OD1  1 
ATOM   3290 N  ND2  . ASN A 1 213 ? 128.746 183.314 151.886 1.00 93.26  ? 224 ASN A ND2  1 
ATOM   3291 H  H    . ASN A 1 213 ? 127.798 183.011 149.683 1.00 92.59  ? 224 ASN A H    1 
ATOM   3292 H  HA   . ASN A 1 213 ? 125.895 184.858 149.433 1.00 93.70  ? 224 ASN A HA   1 
ATOM   3293 H  HB2  . ASN A 1 213 ? 126.489 185.509 151.573 1.00 92.85  ? 224 ASN A HB2  1 
ATOM   3294 H  HB3  . ASN A 1 213 ? 126.348 183.926 151.544 1.00 93.09  ? 224 ASN A HB3  1 
ATOM   3295 H  HD21 . ASN A 1 213 ? 129.541 183.185 152.187 1.00 92.89  ? 224 ASN A HD21 1 
ATOM   3296 H  HD22 . ASN A 1 213 ? 128.256 182.644 151.662 1.00 92.82  ? 224 ASN A HD22 1 
ATOM   3297 N  N    . LEU A 1 214 ? 128.386 185.724 148.099 1.00 87.89  ? 225 LEU A N    1 
ATOM   3298 C  CA   . LEU A 1 214 ? 129.227 186.773 147.545 1.00 91.37  ? 225 LEU A CA   1 
ATOM   3299 C  C    . LEU A 1 214 ? 128.691 187.236 146.196 1.00 90.47  ? 225 LEU A C    1 
ATOM   3300 O  O    . LEU A 1 214 ? 128.120 186.453 145.431 1.00 88.27  ? 225 LEU A O    1 
ATOM   3301 C  CB   . LEU A 1 214 ? 130.672 186.288 147.388 1.00 91.82  ? 225 LEU A CB   1 
ATOM   3302 C  CG   . LEU A 1 214 ? 131.574 186.477 148.609 1.00 93.30  ? 225 LEU A CG   1 
ATOM   3303 C  CD1  . LEU A 1 214 ? 131.931 187.942 148.782 1.00 88.14  ? 225 LEU A CD1  1 
ATOM   3304 C  CD2  . LEU A 1 214 ? 130.902 185.941 149.863 1.00 92.88  ? 225 LEU A CD2  1 
ATOM   3305 H  H    . LEU A 1 214 ? 128.428 184.987 147.658 1.00 89.36  ? 225 LEU A H    1 
ATOM   3306 H  HA   . LEU A 1 214 ? 129.228 187.535 148.146 1.00 90.28  ? 225 LEU A HA   1 
ATOM   3307 H  HB2  . LEU A 1 214 ? 130.655 185.340 147.185 1.00 89.79  ? 225 LEU A HB2  1 
ATOM   3308 H  HB3  . LEU A 1 214 ? 131.078 186.769 146.650 1.00 90.07  ? 225 LEU A HB3  1 
ATOM   3309 H  HG   . LEU A 1 214 ? 132.397 185.981 148.475 1.00 90.09  ? 225 LEU A HG   1 
ATOM   3310 H  HD11 . LEU A 1 214 ? 132.581 188.027 149.496 1.00 89.28  ? 225 LEU A HD11 1 
ATOM   3311 H  HD12 . LEU A 1 214 ? 132.306 188.272 147.951 1.00 89.62  ? 225 LEU A HD12 1 
ATOM   3312 H  HD13 . LEU A 1 214 ? 131.128 188.440 149.003 1.00 89.28  ? 225 LEU A HD13 1 
ATOM   3313 H  HD21 . LEU A 1 214 ? 131.568 185.844 150.561 1.00 89.93  ? 225 LEU A HD21 1 
ATOM   3314 H  HD22 . LEU A 1 214 ? 130.216 186.566 150.146 1.00 89.84  ? 225 LEU A HD22 1 
ATOM   3315 H  HD23 . LEU A 1 214 ? 130.503 185.080 149.664 1.00 90.17  ? 225 LEU A HD23 1 
ATOM   3316 N  N    . PHE A 1 215 ? 128.885 188.524 145.915 1.00 87.66  ? 226 PHE A N    1 
ATOM   3317 C  CA   . PHE A 1 215 ? 128.503 189.130 144.638 1.00 83.48  ? 226 PHE A CA   1 
ATOM   3318 C  C    . PHE A 1 215 ? 129.696 189.947 144.155 1.00 83.77  ? 226 PHE A C    1 
ATOM   3319 O  O    . PHE A 1 215 ? 129.925 191.062 144.634 1.00 89.68  ? 226 PHE A O    1 
ATOM   3320 C  CB   . PHE A 1 215 ? 127.259 190.002 144.779 1.00 83.34  ? 226 PHE A CB   1 
ATOM   3321 C  CG   . PHE A 1 215 ? 126.652 190.420 143.465 1.00 83.83  ? 226 PHE A CG   1 
ATOM   3322 C  CD1  . PHE A 1 215 ? 127.324 191.287 142.617 1.00 80.05  ? 226 PHE A CD1  1 
ATOM   3323 C  CD2  . PHE A 1 215 ? 125.397 189.970 143.092 1.00 87.41  ? 226 PHE A CD2  1 
ATOM   3324 C  CE1  . PHE A 1 215 ? 126.768 191.678 141.415 1.00 82.09  ? 226 PHE A CE1  1 
ATOM   3325 C  CE2  . PHE A 1 215 ? 124.834 190.358 141.890 1.00 86.66  ? 226 PHE A CE2  1 
ATOM   3326 C  CZ   . PHE A 1 215 ? 125.520 191.215 141.052 1.00 84.51  ? 226 PHE A CZ   1 
ATOM   3327 H  H    . PHE A 1 215 ? 129.248 189.082 146.461 1.00 85.14  ? 226 PHE A H    1 
ATOM   3328 H  HA   . PHE A 1 215 ? 128.321 188.434 143.987 1.00 84.30  ? 226 PHE A HA   1 
ATOM   3329 H  HB2  . PHE A 1 215 ? 126.586 189.509 145.273 1.00 84.22  ? 226 PHE A HB2  1 
ATOM   3330 H  HB3  . PHE A 1 215 ? 127.496 190.808 145.259 1.00 84.84  ? 226 PHE A HB3  1 
ATOM   3331 H  HD1  . PHE A 1 215 ? 128.167 191.601 142.855 1.00 83.49  ? 226 PHE A HD1  1 
ATOM   3332 H  HD2  . PHE A 1 215 ? 124.931 189.391 143.651 1.00 84.61  ? 226 PHE A HD2  1 
ATOM   3333 H  HE1  . PHE A 1 215 ? 127.232 192.256 140.853 1.00 83.79  ? 226 PHE A HE1  1 
ATOM   3334 H  HE2  . PHE A 1 215 ? 123.993 190.045 141.647 1.00 84.49  ? 226 PHE A HE2  1 
ATOM   3335 H  HZ   . PHE A 1 215 ? 125.142 191.478 140.243 1.00 83.91  ? 226 PHE A HZ   1 
ATOM   3336 N  N    . TYR A 1 216 ? 130.447 189.394 143.209 1.00 78.29  ? 227 TYR A N    1 
ATOM   3337 C  CA   . TYR A 1 216 ? 131.601 190.078 142.645 1.00 80.45  ? 227 TYR A CA   1 
ATOM   3338 C  C    . TYR A 1 216 ? 131.194 190.823 141.383 1.00 78.01  ? 227 TYR A C    1 
ATOM   3339 O  O    . TYR A 1 216 ? 130.633 190.229 140.456 1.00 82.42  ? 227 TYR A O    1 
ATOM   3340 C  CB   . TYR A 1 216 ? 132.724 189.088 142.334 1.00 81.30  ? 227 TYR A CB   1 
ATOM   3341 C  CG   . TYR A 1 216 ? 133.374 188.488 143.558 1.00 80.65  ? 227 TYR A CG   1 
ATOM   3342 C  CD1  . TYR A 1 216 ? 134.087 189.282 144.445 1.00 73.69  ? 227 TYR A CD1  1 
ATOM   3343 C  CD2  . TYR A 1 216 ? 133.275 187.132 143.828 1.00 80.82  ? 227 TYR A CD2  1 
ATOM   3344 C  CE1  . TYR A 1 216 ? 134.683 188.744 145.563 1.00 71.46  ? 227 TYR A CE1  1 
ATOM   3345 C  CE2  . TYR A 1 216 ? 133.868 186.583 144.947 1.00 80.65  ? 227 TYR A CE2  1 
ATOM   3346 C  CZ   . TYR A 1 216 ? 134.571 187.394 145.811 1.00 76.93  ? 227 TYR A CZ   1 
ATOM   3347 O  OH   . TYR A 1 216 ? 135.165 186.854 146.928 1.00 82.31  ? 227 TYR A OH   1 
ATOM   3348 H  H    . TYR A 1 216 ? 130.302 188.618 142.869 1.00 78.92  ? 227 TYR A H    1 
ATOM   3349 H  HA   . TYR A 1 216 ? 131.936 190.725 143.287 1.00 79.17  ? 227 TYR A HA   1 
ATOM   3350 H  HB2  . TYR A 1 216 ? 132.360 188.358 141.807 1.00 79.04  ? 227 TYR A HB2  1 
ATOM   3351 H  HB3  . TYR A 1 216 ? 133.413 189.546 141.829 1.00 79.06  ? 227 TYR A HB3  1 
ATOM   3352 H  HD1  . TYR A 1 216 ? 134.164 190.194 144.280 1.00 77.89  ? 227 TYR A HD1  1 
ATOM   3353 H  HD2  . TYR A 1 216 ? 132.801 186.585 143.245 1.00 79.00  ? 227 TYR A HD2  1 
ATOM   3354 H  HE1  . TYR A 1 216 ? 135.157 189.290 146.148 1.00 77.90  ? 227 TYR A HE1  1 
ATOM   3355 H  HE2  . TYR A 1 216 ? 133.794 185.671 145.115 1.00 79.41  ? 227 TYR A HE2  1 
ATOM   3356 H  HH   . TYR A 1 216 ? 135.544 187.459 147.371 1.00 79.43  ? 227 TYR A HH   1 
ATOM   3357 N  N    . ASP A 1 217 ? 131.477 192.123 141.355 1.00 73.23  ? 228 ASP A N    1 
ATOM   3358 C  CA   . ASP A 1 217 ? 131.256 192.944 140.176 1.00 73.92  ? 228 ASP A CA   1 
ATOM   3359 C  C    . ASP A 1 217 ? 132.369 193.974 140.102 1.00 71.43  ? 228 ASP A C    1 
ATOM   3360 O  O    . ASP A 1 217 ? 132.872 194.437 141.128 1.00 79.97  ? 228 ASP A O    1 
ATOM   3361 C  CB   . ASP A 1 217 ? 129.892 193.645 140.200 1.00 78.83  ? 228 ASP A CB   1 
ATOM   3362 C  CG   . ASP A 1 217 ? 129.588 194.291 141.538 1.00 83.81  ? 228 ASP A CG   1 
ATOM   3363 O  OD1  . ASP A 1 217 ? 130.530 194.500 142.330 1.00 86.41  ? 228 ASP A OD1  1 
ATOM   3364 O  OD2  . ASP A 1 217 ? 128.406 194.601 141.792 1.00 86.38  ? 228 ASP A OD2  1 
ATOM   3365 H  H    . ASP A 1 217 ? 131.810 192.555 142.020 1.00 78.61  ? 228 ASP A H    1 
ATOM   3366 H  HA   . ASP A 1 217 ? 131.308 192.387 139.385 1.00 79.01  ? 228 ASP A HA   1 
ATOM   3367 H  HB2  . ASP A 1 217 ? 129.889 194.342 139.526 1.00 79.16  ? 228 ASP A HB2  1 
ATOM   3368 H  HB3  . ASP A 1 217 ? 129.194 192.999 140.013 1.00 79.11  ? 228 ASP A HB3  1 
ATOM   3369 N  N    . VAL A 1 218 ? 132.746 194.330 138.884 1.00 67.06  ? 229 VAL A N    1 
ATOM   3370 C  CA   . VAL A 1 218 ? 133.866 195.233 138.648 1.00 68.60  ? 229 VAL A CA   1 
ATOM   3371 C  C    . VAL A 1 218 ? 133.343 196.370 137.779 1.00 69.15  ? 229 VAL A C    1 
ATOM   3372 O  O    . VAL A 1 218 ? 133.338 196.289 136.548 1.00 77.86  ? 229 VAL A O    1 
ATOM   3373 C  CB   . VAL A 1 218 ? 135.057 194.530 137.995 1.00 77.39  ? 229 VAL A CB   1 
ATOM   3374 C  CG1  . VAL A 1 218 ? 136.176 195.517 137.811 1.00 77.04  ? 229 VAL A CG1  1 
ATOM   3375 C  CG2  . VAL A 1 218 ? 135.527 193.329 138.835 1.00 77.27  ? 229 VAL A CG2  1 
ATOM   3376 H  H    . VAL A 1 218 ? 132.354 194.074 138.163 1.00 74.79  ? 229 VAL A H    1 
ATOM   3377 H  HA   . VAL A 1 218 ? 134.160 195.609 139.492 1.00 74.52  ? 229 VAL A HA   1 
ATOM   3378 H  HB   . VAL A 1 218 ? 134.795 194.205 137.119 1.00 75.89  ? 229 VAL A HB   1 
ATOM   3379 H  HG11 . VAL A 1 218 ? 137.004 195.091 138.077 1.00 74.77  ? 229 VAL A HG11 1 
ATOM   3380 H  HG12 . VAL A 1 218 ? 136.207 195.783 136.878 1.00 75.31  ? 229 VAL A HG12 1 
ATOM   3381 H  HG13 . VAL A 1 218 ? 136.014 196.291 138.374 1.00 75.14  ? 229 VAL A HG13 1 
ATOM   3382 H  HG21 . VAL A 1 218 ? 136.275 192.903 138.385 1.00 74.94  ? 229 VAL A HG21 1 
ATOM   3383 H  HG22 . VAL A 1 218 ? 135.810 193.643 139.708 1.00 75.28  ? 229 VAL A HG22 1 
ATOM   3384 H  HG23 . VAL A 1 218 ? 134.802 192.693 138.934 1.00 75.87  ? 229 VAL A HG23 1 
ATOM   3385 N  N    . GLN A 1 219 ? 132.905 197.448 138.418 1.00 72.05  ? 230 GLN A N    1 
ATOM   3386 C  CA   . GLN A 1 219 ? 132.461 198.624 137.689 1.00 74.76  ? 230 GLN A CA   1 
ATOM   3387 C  C    . GLN A 1 219 ? 133.660 199.419 137.191 1.00 77.18  ? 230 GLN A C    1 
ATOM   3388 O  O    . GLN A 1 219 ? 134.755 199.353 137.757 1.00 81.64  ? 230 GLN A O    1 
ATOM   3389 C  CB   . GLN A 1 219 ? 131.577 199.500 138.574 1.00 83.76  ? 230 GLN A CB   1 
ATOM   3390 C  CG   . GLN A 1 219 ? 130.575 200.354 137.805 1.00 92.19  ? 230 GLN A CG   1 
ATOM   3391 C  CD   . GLN A 1 219 ? 131.166 201.674 137.341 1.00 92.35  ? 230 GLN A CD   1 
ATOM   3392 O  OE1  . GLN A 1 219 ? 131.826 202.374 138.110 1.00 88.92  ? 230 GLN A OE1  1 
ATOM   3393 N  NE2  . GLN A 1 219 ? 130.936 202.018 136.078 1.00 90.70  ? 230 GLN A NE2  1 
ATOM   3394 H  H    . GLN A 1 219 ? 132.857 197.522 139.273 1.00 82.95  ? 230 GLN A H    1 
ATOM   3395 H  HA   . GLN A 1 219 ? 131.941 198.341 136.921 1.00 83.63  ? 230 GLN A HA   1 
ATOM   3396 H  HB2  . GLN A 1 219 ? 131.078 198.925 139.176 1.00 84.35  ? 230 GLN A HB2  1 
ATOM   3397 H  HB3  . GLN A 1 219 ? 132.146 200.095 139.088 1.00 84.60  ? 230 GLN A HB3  1 
ATOM   3398 H  HG2  . GLN A 1 219 ? 130.276 199.868 137.021 1.00 85.40  ? 230 GLN A HG2  1 
ATOM   3399 H  HG3  . GLN A 1 219 ? 129.820 200.547 138.381 1.00 85.84  ? 230 GLN A HG3  1 
ATOM   3400 H  HE21 . GLN A 1 219 ? 130.472 201.505 135.568 1.00 85.16  ? 230 GLN A HE21 1 
ATOM   3401 H  HE22 . GLN A 1 219 ? 131.252 202.757 135.771 1.00 84.96  ? 230 GLN A HE22 1 
ATOM   3402 N  N    . PHE A 1 220 ? 133.446 200.173 136.118 1.00 87.10  ? 231 PHE A N    1 
ATOM   3403 C  CA   . PHE A 1 220 ? 134.503 200.944 135.477 1.00 94.83  ? 231 PHE A CA   1 
ATOM   3404 C  C    . PHE A 1 220 ? 134.370 202.410 135.872 1.00 93.02  ? 231 PHE A C    1 
ATOM   3405 O  O    . PHE A 1 220 ? 133.309 203.015 135.684 1.00 86.13  ? 231 PHE A O    1 
ATOM   3406 C  CB   . PHE A 1 220 ? 134.440 200.786 133.958 1.00 96.96  ? 231 PHE A CB   1 
ATOM   3407 C  CG   . PHE A 1 220 ? 134.748 199.395 133.484 1.00 95.91  ? 231 PHE A CG   1 
ATOM   3408 C  CD1  . PHE A 1 220 ? 135.910 198.756 133.880 1.00 95.61  ? 231 PHE A CD1  1 
ATOM   3409 C  CD2  . PHE A 1 220 ? 133.872 198.722 132.648 1.00 91.87  ? 231 PHE A CD2  1 
ATOM   3410 C  CE1  . PHE A 1 220 ? 136.196 197.477 133.451 1.00 93.13  ? 231 PHE A CE1  1 
ATOM   3411 C  CE2  . PHE A 1 220 ? 134.154 197.441 132.214 1.00 91.90  ? 231 PHE A CE2  1 
ATOM   3412 C  CZ   . PHE A 1 220 ? 135.318 196.818 132.617 1.00 91.86  ? 231 PHE A CZ   1 
ATOM   3413 H  H    . PHE A 1 220 ? 132.681 200.252 135.733 1.00 91.01  ? 231 PHE A H    1 
ATOM   3414 H  HA   . PHE A 1 220 ? 135.366 200.626 135.784 1.00 92.27  ? 231 PHE A HA   1 
ATOM   3415 H  HB2  . PHE A 1 220 ? 133.550 201.018 133.652 1.00 92.37  ? 231 PHE A HB2  1 
ATOM   3416 H  HB3  . PHE A 1 220 ? 135.092 201.383 133.559 1.00 92.84  ? 231 PHE A HB3  1 
ATOM   3417 H  HD1  . PHE A 1 220 ? 136.504 199.197 134.442 1.00 92.29  ? 231 PHE A HD1  1 
ATOM   3418 H  HD2  . PHE A 1 220 ? 133.087 199.138 132.374 1.00 92.07  ? 231 PHE A HD2  1 
ATOM   3419 H  HE1  . PHE A 1 220 ? 136.982 197.060 133.724 1.00 92.10  ? 231 PHE A HE1  1 
ATOM   3420 H  HE2  . PHE A 1 220 ? 133.560 196.999 131.652 1.00 92.47  ? 231 PHE A HE2  1 
ATOM   3421 H  HZ   . PHE A 1 220 ? 135.510 195.956 132.326 1.00 92.13  ? 231 PHE A HZ   1 
ATOM   3422 N  N    . LYS A 1 221 ? 135.451 202.976 136.415 1.00 103.69 ? 232 LYS A N    1 
ATOM   3423 C  CA   . LYS A 1 221 ? 135.429 204.374 136.837 1.00 103.94 ? 232 LYS A CA   1 
ATOM   3424 C  C    . LYS A 1 221 ? 135.164 205.301 135.658 1.00 103.28 ? 232 LYS A C    1 
ATOM   3425 O  O    . LYS A 1 221 ? 134.357 206.233 135.754 1.00 101.55 ? 232 LYS A O    1 
ATOM   3426 C  CB   . LYS A 1 221 ? 136.754 204.736 137.508 1.00 101.73 ? 232 LYS A CB   1 
ATOM   3427 C  CG   . LYS A 1 221 ? 136.672 205.925 138.449 1.00 99.59  ? 232 LYS A CG   1 
ATOM   3428 C  CD   . LYS A 1 221 ? 138.047 206.316 138.964 1.00 102.26 ? 232 LYS A CD   1 
ATOM   3429 C  CE   . LYS A 1 221 ? 138.015 207.641 139.703 1.00 102.17 ? 232 LYS A CE   1 
ATOM   3430 N  NZ   . LYS A 1 221 ? 139.133 207.755 140.679 1.00 104.21 ? 232 LYS A NZ   1 
ATOM   3431 H  H    . LYS A 1 221 ? 136.200 202.575 136.547 1.00 101.24 ? 232 LYS A H    1 
ATOM   3432 H  HA   . LYS A 1 221 ? 134.719 204.499 137.486 1.00 101.32 ? 232 LYS A HA   1 
ATOM   3433 H  HB2  . LYS A 1 221 ? 137.067 203.973 138.019 1.00 101.32 ? 232 LYS A HB2  1 
ATOM   3434 H  HB3  . LYS A 1 221 ? 137.396 204.956 136.816 1.00 101.31 ? 232 LYS A HB3  1 
ATOM   3435 H  HG2  . LYS A 1 221 ? 136.301 206.684 137.972 1.00 101.28 ? 232 LYS A HG2  1 
ATOM   3436 H  HG3  . LYS A 1 221 ? 136.114 205.698 139.209 1.00 100.87 ? 232 LYS A HG3  1 
ATOM   3437 H  HD2  . LYS A 1 221 ? 138.368 205.633 139.575 1.00 101.69 ? 232 LYS A HD2  1 
ATOM   3438 H  HD3  . LYS A 1 221 ? 138.653 206.409 138.214 1.00 101.57 ? 232 LYS A HD3  1 
ATOM   3439 H  HE2  . LYS A 1 221 ? 138.099 208.363 139.062 1.00 101.29 ? 232 LYS A HE2  1 
ATOM   3440 H  HE3  . LYS A 1 221 ? 137.177 207.719 140.184 1.00 101.49 ? 232 LYS A HE3  1 
ATOM   3441 H  HZ1  . LYS A 1 221 ? 139.049 208.503 141.154 1.00 101.88 ? 232 LYS A HZ1  1 
ATOM   3442 H  HZ2  . LYS A 1 221 ? 139.125 207.058 141.231 1.00 101.95 ? 232 LYS A HZ2  1 
ATOM   3443 H  HZ3  . LYS A 1 221 ? 139.912 207.771 140.247 1.00 101.82 ? 232 LYS A HZ3  1 
ATOM   3444 N  N    . GLU A 1 222 ? 135.842 205.064 134.534 1.00 107.75 ? 233 GLU A N    1 
ATOM   3445 C  CA   . GLU A 1 222 ? 135.657 205.923 133.370 1.00 106.88 ? 233 GLU A CA   1 
ATOM   3446 C  C    . GLU A 1 222 ? 134.233 205.824 132.839 1.00 102.35 ? 233 GLU A C    1 
ATOM   3447 O  O    . GLU A 1 222 ? 133.655 206.823 132.397 1.00 102.02 ? 233 GLU A O    1 
ATOM   3448 C  CB   . GLU A 1 222 ? 136.664 205.555 132.280 1.00 106.21 ? 233 GLU A CB   1 
ATOM   3449 C  CG   . GLU A 1 222 ? 138.097 205.409 132.777 1.00 109.10 ? 233 GLU A CG   1 
ATOM   3450 C  CD   . GLU A 1 222 ? 138.479 206.471 133.790 1.00 108.30 ? 233 GLU A CD   1 
ATOM   3451 O  OE1  . GLU A 1 222 ? 138.451 207.670 133.439 1.00 106.22 ? 233 GLU A OE1  1 
ATOM   3452 O  OE2  . GLU A 1 222 ? 138.806 206.108 134.940 1.00 106.88 ? 233 GLU A OE2  1 
ATOM   3453 H  H    . GLU A 1 222 ? 136.404 204.423 134.424 1.00 105.92 ? 233 GLU A H    1 
ATOM   3454 H  HA   . GLU A 1 222 ? 135.813 206.845 133.627 1.00 106.40 ? 233 GLU A HA   1 
ATOM   3455 H  HB2  . GLU A 1 222 ? 136.401 204.708 131.887 1.00 105.68 ? 233 GLU A HB2  1 
ATOM   3456 H  HB3  . GLU A 1 222 ? 136.656 206.248 131.601 1.00 105.91 ? 233 GLU A HB3  1 
ATOM   3457 H  HG2  . GLU A 1 222 ? 138.198 204.542 133.199 1.00 106.58 ? 233 GLU A HG2  1 
ATOM   3458 H  HG3  . GLU A 1 222 ? 138.702 205.484 132.022 1.00 106.30 ? 233 GLU A HG3  1 
ATOM   3459 N  N    . LEU A 1 223 ? 133.651 204.625 132.877 1.00 100.12 ? 234 LEU A N    1 
ATOM   3460 C  CA   . LEU A 1 223 ? 132.288 204.450 132.388 1.00 106.36 ? 234 LEU A CA   1 
ATOM   3461 C  C    . LEU A 1 223 ? 131.304 205.304 133.178 1.00 106.78 ? 234 LEU A C    1 
ATOM   3462 O  O    . LEU A 1 223 ? 130.406 205.927 132.600 1.00 104.87 ? 234 LEU A O    1 
ATOM   3463 C  CB   . LEU A 1 223 ? 131.894 202.975 132.462 1.00 104.66 ? 234 LEU A CB   1 
ATOM   3464 C  CG   . LEU A 1 223 ? 130.538 202.594 131.866 1.00 102.86 ? 234 LEU A CG   1 
ATOM   3465 C  CD1  . LEU A 1 223 ? 130.402 203.112 130.443 1.00 101.64 ? 234 LEU A CD1  1 
ATOM   3466 C  CD2  . LEU A 1 223 ? 130.347 201.087 131.912 1.00 102.03 ? 234 LEU A CD2  1 
ATOM   3467 H  H    . LEU A 1 223 ? 134.018 203.908 133.178 1.00 102.03 ? 234 LEU A H    1 
ATOM   3468 H  HA   . LEU A 1 223 ? 132.251 204.730 131.460 1.00 103.18 ? 234 LEU A HA   1 
ATOM   3469 H  HB2  . LEU A 1 223 ? 132.569 202.458 131.994 1.00 102.35 ? 234 LEU A HB2  1 
ATOM   3470 H  HB3  . LEU A 1 223 ? 131.881 202.712 133.396 1.00 102.33 ? 234 LEU A HB3  1 
ATOM   3471 H  HG   . LEU A 1 223 ? 129.836 203.000 132.399 1.00 102.46 ? 234 LEU A HG   1 
ATOM   3472 H  HD11 . LEU A 1 223 ? 129.707 202.612 129.988 1.00 102.31 ? 234 LEU A HD11 1 
ATOM   3473 H  HD12 . LEU A 1 223 ? 130.170 204.054 130.470 1.00 102.56 ? 234 LEU A HD12 1 
ATOM   3474 H  HD13 . LEU A 1 223 ? 131.249 202.993 129.985 1.00 102.30 ? 234 LEU A HD13 1 
ATOM   3475 H  HD21 . LEU A 1 223 ? 129.512 200.859 131.473 1.00 102.56 ? 234 LEU A HD21 1 
ATOM   3476 H  HD22 . LEU A 1 223 ? 131.089 200.662 131.454 1.00 102.32 ? 234 LEU A HD22 1 
ATOM   3477 H  HD23 . LEU A 1 223 ? 130.323 200.800 132.839 1.00 102.17 ? 234 LEU A HD23 1 
ATOM   3478 N  N    . ILE A 1 224 ? 131.457 205.344 134.496 1.00 95.57  ? 235 ILE A N    1 
ATOM   3479 C  CA   . ILE A 1 224 ? 130.546 206.094 135.352 1.00 91.45  ? 235 ILE A CA   1 
ATOM   3480 C  C    . ILE A 1 224 ? 130.966 207.557 135.381 1.00 90.89  ? 235 ILE A C    1 
ATOM   3481 O  O    . ILE A 1 224 ? 132.150 207.881 135.539 1.00 86.86  ? 235 ILE A O    1 
ATOM   3482 C  CB   . ILE A 1 224 ? 130.512 205.487 136.767 1.00 90.35  ? 235 ILE A CB   1 
ATOM   3483 C  CG1  . ILE A 1 224 ? 129.521 206.243 137.657 1.00 93.31  ? 235 ILE A CG1  1 
ATOM   3484 C  CG2  . ILE A 1 224 ? 131.896 205.497 137.400 1.00 87.43  ? 235 ILE A CG2  1 
ATOM   3485 C  CD1  . ILE A 1 224 ? 128.081 206.137 137.202 1.00 93.10  ? 235 ILE A CD1  1 
ATOM   3486 H  H    . ILE A 1 224 ? 132.087 204.941 134.917 1.00 92.83  ? 235 ILE A H    1 
ATOM   3487 H  HA   . ILE A 1 224 ? 129.653 206.045 134.979 1.00 92.25  ? 235 ILE A HA   1 
ATOM   3488 H  HB   . ILE A 1 224 ? 130.217 204.566 136.696 1.00 91.94  ? 235 ILE A HB   1 
ATOM   3489 H  HG12 . ILE A 1 224 ? 129.575 205.878 138.552 1.00 91.76  ? 235 ILE A HG12 1 
ATOM   3490 H  HG13 . ILE A 1 224 ? 129.759 207.183 137.677 1.00 92.62  ? 235 ILE A HG13 1 
ATOM   3491 H  HG21 . ILE A 1 224 ? 131.841 205.076 138.271 1.00 91.43  ? 235 ILE A HG21 1 
ATOM   3492 H  HG22 . ILE A 1 224 ? 132.512 205.003 136.839 1.00 91.38  ? 235 ILE A HG22 1 
ATOM   3493 H  HG23 . ILE A 1 224 ? 132.197 206.413 137.496 1.00 91.88  ? 235 ILE A HG23 1 
ATOM   3494 H  HD11 . ILE A 1 224 ? 127.506 206.511 137.888 1.00 92.44  ? 235 ILE A HD11 1 
ATOM   3495 H  HD12 . ILE A 1 224 ? 127.972 206.630 136.374 1.00 92.03  ? 235 ILE A HD12 1 
ATOM   3496 H  HD13 . ILE A 1 224 ? 127.862 205.202 137.063 1.00 91.87  ? 235 ILE A HD13 1 
ATOM   3497 N  N    . SER A 1 225 ? 129.988 208.451 135.222 1.00 101.83 ? 236 SER A N    1 
ATOM   3498 C  CA   . SER A 1 225 ? 130.279 209.882 135.225 1.00 102.22 ? 236 SER A CA   1 
ATOM   3499 C  C    . SER A 1 225 ? 130.811 210.330 136.581 1.00 101.74 ? 236 SER A C    1 
ATOM   3500 O  O    . SER A 1 225 ? 131.803 211.063 136.661 1.00 102.78 ? 236 SER A O    1 
ATOM   3501 C  CB   . SER A 1 225 ? 129.021 210.669 134.855 1.00 100.97 ? 236 SER A CB   1 
ATOM   3502 O  OG   . SER A 1 225 ? 127.963 210.388 135.755 1.00 101.37 ? 236 SER A OG   1 
ATOM   3503 H  H    . SER A 1 225 ? 129.157 208.256 135.112 1.00 100.76 ? 236 SER A H    1 
ATOM   3504 H  HA   . SER A 1 225 ? 130.958 210.068 134.558 1.00 100.93 ? 236 SER A HA   1 
ATOM   3505 H  HB2  . SER A 1 225 ? 129.221 211.617 134.889 1.00 100.92 ? 236 SER A HB2  1 
ATOM   3506 H  HB3  . SER A 1 225 ? 128.746 210.420 133.959 1.00 100.82 ? 236 SER A HB3  1 
ATOM   3507 H  HG   . SER A 1 225 ? 127.285 210.841 135.552 1.00 101.05 ? 236 SER A HG   1 
ATOM   3508 N  N    . ASP A 1 226 ? 130.160 209.897 137.662 1.00 93.33  ? 237 ASP A N    1 
ATOM   3509 C  CA   . ASP A 1 226 ? 130.546 210.245 139.029 1.00 90.71  ? 237 ASP A CA   1 
ATOM   3510 C  C    . ASP A 1 226 ? 130.747 208.951 139.808 1.00 88.36  ? 237 ASP A C    1 
ATOM   3511 O  O    . ASP A 1 226 ? 129.816 208.461 140.467 1.00 85.41  ? 237 ASP A O    1 
ATOM   3512 C  CB   . ASP A 1 226 ? 129.493 211.131 139.692 1.00 90.91  ? 237 ASP A CB   1 
ATOM   3513 C  CG   . ASP A 1 226 ? 128.084 210.606 139.502 1.00 93.61  ? 237 ASP A CG   1 
ATOM   3514 O  OD1  . ASP A 1 226 ? 127.922 209.561 138.837 1.00 94.15  ? 237 ASP A OD1  1 
ATOM   3515 O  OD2  . ASP A 1 226 ? 127.138 211.238 140.017 1.00 91.73  ? 237 ASP A OD2  1 
ATOM   3516 H  H    . ASP A 1 226 ? 129.471 209.385 137.626 1.00 92.12  ? 237 ASP A H    1 
ATOM   3517 H  HA   . ASP A 1 226 ? 131.379 210.739 139.015 1.00 91.57  ? 237 ASP A HA   1 
ATOM   3518 H  HB2  . ASP A 1 226 ? 129.671 211.176 140.644 1.00 91.12  ? 237 ASP A HB2  1 
ATOM   3519 H  HB3  . ASP A 1 226 ? 129.537 212.019 139.304 1.00 91.45  ? 237 ASP A HB3  1 
ATOM   3520 N  N    . PRO A 1 227 ? 131.944 208.360 139.761 1.00 99.46  ? 238 PRO A N    1 
ATOM   3521 C  CA   . PRO A 1 227 ? 132.141 207.073 140.447 1.00 101.37 ? 238 PRO A CA   1 
ATOM   3522 C  C    . PRO A 1 227 ? 131.901 207.144 141.943 1.00 103.63 ? 238 PRO A C    1 
ATOM   3523 O  O    . PRO A 1 227 ? 131.474 206.148 142.541 1.00 106.78 ? 238 PRO A O    1 
ATOM   3524 C  CB   . PRO A 1 227 ? 133.599 206.725 140.119 1.00 102.05 ? 238 PRO A CB   1 
ATOM   3525 C  CG   . PRO A 1 227 ? 134.251 208.040 139.879 1.00 103.22 ? 238 PRO A CG   1 
ATOM   3526 C  CD   . PRO A 1 227 ? 133.207 208.899 139.228 1.00 103.06 ? 238 PRO A CD   1 
ATOM   3527 H  HA   . PRO A 1 227 ? 131.558 206.399 140.065 1.00 100.50 ? 238 PRO A HA   1 
ATOM   3528 H  HB2  . PRO A 1 227 ? 134.003 206.267 140.871 1.00 101.02 ? 238 PRO A HB2  1 
ATOM   3529 H  HB3  . PRO A 1 227 ? 133.636 206.173 139.323 1.00 100.75 ? 238 PRO A HB3  1 
ATOM   3530 H  HG2  . PRO A 1 227 ? 134.529 208.425 140.724 1.00 101.48 ? 238 PRO A HG2  1 
ATOM   3531 H  HG3  . PRO A 1 227 ? 135.012 207.926 139.289 1.00 101.11 ? 238 PRO A HG3  1 
ATOM   3532 H  HD2  . PRO A 1 227 ? 133.323 209.824 139.495 1.00 101.19 ? 238 PRO A HD2  1 
ATOM   3533 H  HD3  . PRO A 1 227 ? 133.239 208.799 138.264 1.00 101.02 ? 238 PRO A HD3  1 
ATOM   3534 N  N    . TYR A 1 228 ? 132.171 208.289 142.572 1.00 97.75  ? 239 TYR A N    1 
ATOM   3535 C  CA   . TYR A 1 228 ? 131.926 208.416 144.004 1.00 95.44  ? 239 TYR A CA   1 
ATOM   3536 C  C    . TYR A 1 228 ? 130.438 208.327 144.316 1.00 88.79  ? 239 TYR A C    1 
ATOM   3537 O  O    . TYR A 1 228 ? 130.043 207.725 145.319 1.00 80.00  ? 239 TYR A O    1 
ATOM   3538 C  CB   . TYR A 1 228 ? 132.516 209.728 144.518 1.00 91.88  ? 239 TYR A CB   1 
ATOM   3539 C  CG   . TYR A 1 228 ? 134.028 209.731 144.542 1.00 89.26  ? 239 TYR A CG   1 
ATOM   3540 C  CD1  . TYR A 1 228 ? 134.729 208.912 145.418 1.00 91.13  ? 239 TYR A CD1  1 
ATOM   3541 C  CD2  . TYR A 1 228 ? 134.753 210.538 143.678 1.00 86.96  ? 239 TYR A CD2  1 
ATOM   3542 C  CE1  . TYR A 1 228 ? 136.110 208.905 145.438 1.00 91.38  ? 239 TYR A CE1  1 
ATOM   3543 C  CE2  . TYR A 1 228 ? 136.134 210.538 143.691 1.00 87.36  ? 239 TYR A CE2  1 
ATOM   3544 C  CZ   . TYR A 1 228 ? 136.807 209.720 144.571 1.00 89.30  ? 239 TYR A CZ   1 
ATOM   3545 O  OH   . TYR A 1 228 ? 138.183 209.719 144.588 1.00 90.39  ? 239 TYR A OH   1 
ATOM   3546 H  H    . TYR A 1 228 ? 132.491 208.994 142.198 1.00 91.53  ? 239 TYR A H    1 
ATOM   3547 H  HA   . TYR A 1 228 ? 132.370 207.687 144.465 1.00 91.23  ? 239 TYR A HA   1 
ATOM   3548 H  HB2  . TYR A 1 228 ? 132.225 210.451 143.941 1.00 90.70  ? 239 TYR A HB2  1 
ATOM   3549 H  HB3  . TYR A 1 228 ? 132.202 209.881 145.423 1.00 90.14  ? 239 TYR A HB3  1 
ATOM   3550 H  HD1  . TYR A 1 228 ? 134.261 208.362 146.004 1.00 90.54  ? 239 TYR A HD1  1 
ATOM   3551 H  HD2  . TYR A 1 228 ? 134.302 211.090 143.082 1.00 89.96  ? 239 TYR A HD2  1 
ATOM   3552 H  HE1  . TYR A 1 228 ? 136.567 208.356 146.033 1.00 90.61  ? 239 TYR A HE1  1 
ATOM   3553 H  HE2  . TYR A 1 228 ? 136.607 211.087 143.108 1.00 90.00  ? 239 TYR A HE2  1 
ATOM   3554 H  HH   . TYR A 1 228 ? 138.479 210.233 143.993 1.00 90.37  ? 239 TYR A HH   1 
ATOM   3555 N  N    . GLY A 1 229 ? 129.595 208.920 143.470 1.00 88.08  ? 240 GLY A N    1 
ATOM   3556 C  CA   . GLY A 1 229 ? 128.163 208.731 143.627 1.00 86.51  ? 240 GLY A CA   1 
ATOM   3557 C  C    . GLY A 1 229 ? 127.758 207.279 143.469 1.00 88.22  ? 240 GLY A C    1 
ATOM   3558 O  O    . GLY A 1 229 ? 126.868 206.789 144.170 1.00 87.88  ? 240 GLY A O    1 
ATOM   3559 H  H    . GLY A 1 229 ? 129.825 209.424 142.812 1.00 88.96  ? 240 GLY A H    1 
ATOM   3560 H  HA2  . GLY A 1 229 ? 127.891 209.032 144.508 1.00 87.80  ? 240 GLY A HA2  1 
ATOM   3561 H  HA3  . GLY A 1 229 ? 127.692 209.257 142.963 1.00 88.55  ? 240 GLY A HA3  1 
ATOM   3562 N  N    . ASN A 1 230 ? 128.403 206.570 142.540 1.00 102.27 ? 241 ASN A N    1 
ATOM   3563 C  CA   . ASN A 1 230 ? 128.120 205.149 142.373 1.00 105.81 ? 241 ASN A CA   1 
ATOM   3564 C  C    . ASN A 1 230 ? 128.493 204.368 143.625 1.00 100.55 ? 241 ASN A C    1 
ATOM   3565 O  O    . ASN A 1 230 ? 127.761 203.464 144.042 1.00 102.12 ? 241 ASN A O    1 
ATOM   3566 C  CB   . ASN A 1 230 ? 128.869 204.605 141.158 1.00 103.12 ? 241 ASN A CB   1 
ATOM   3567 C  CG   . ASN A 1 230 ? 128.419 203.211 140.773 1.00 99.72  ? 241 ASN A CG   1 
ATOM   3568 O  OD1  . ASN A 1 230 ? 127.600 202.598 141.458 1.00 101.21 ? 241 ASN A OD1  1 
ATOM   3569 N  ND2  . ASN A 1 230 ? 128.952 202.701 139.670 1.00 98.71  ? 241 ASN A ND2  1 
ATOM   3570 H  H    . ASN A 1 230 ? 128.998 206.883 142.005 1.00 99.58  ? 241 ASN A H    1 
ATOM   3571 H  HA   . ASN A 1 230 ? 127.170 205.031 142.217 1.00 100.74 ? 241 ASN A HA   1 
ATOM   3572 H  HB2  . ASN A 1 230 ? 128.703 205.191 140.404 1.00 100.10 ? 241 ASN A HB2  1 
ATOM   3573 H  HB3  . ASN A 1 230 ? 129.818 204.574 141.355 1.00 100.23 ? 241 ASN A HB3  1 
ATOM   3574 H  HD21 . ASN A 1 230 ? 129.522 203.159 139.216 1.00 99.73  ? 241 ASN A HD21 1 
ATOM   3575 H  HD22 . ASN A 1 230 ? 128.728 201.914 139.411 1.00 99.99  ? 241 ASN A HD22 1 
ATOM   3576 N  N    . LEU A 1 231 ? 129.634 204.695 144.233 1.00 81.62  ? 242 LEU A N    1 
ATOM   3577 C  CA   . LEU A 1 231 ? 130.010 204.045 145.484 1.00 81.19  ? 242 LEU A CA   1 
ATOM   3578 C  C    . LEU A 1 231 ? 129.030 204.386 146.596 1.00 83.93  ? 242 LEU A C    1 
ATOM   3579 O  O    . LEU A 1 231 ? 128.701 203.531 147.425 1.00 84.65  ? 242 LEU A O    1 
ATOM   3580 C  CB   . LEU A 1 231 ? 131.435 204.437 145.876 1.00 85.97  ? 242 LEU A CB   1 
ATOM   3581 C  CG   . LEU A 1 231 ? 131.998 203.788 147.146 1.00 90.65  ? 242 LEU A CG   1 
ATOM   3582 C  CD1  . LEU A 1 231 ? 132.101 202.272 147.041 1.00 88.82  ? 242 LEU A CD1  1 
ATOM   3583 C  CD2  . LEU A 1 231 ? 133.363 204.379 147.451 1.00 87.88  ? 242 LEU A CD2  1 
ATOM   3584 H  H    . LEU A 1 231 ? 130.197 205.280 143.948 1.00 86.71  ? 242 LEU A H    1 
ATOM   3585 H  HA   . LEU A 1 231 ? 129.984 203.086 145.356 1.00 85.94  ? 242 LEU A HA   1 
ATOM   3586 H  HB2  . LEU A 1 231 ? 132.027 204.201 145.144 1.00 86.50  ? 242 LEU A HB2  1 
ATOM   3587 H  HB3  . LEU A 1 231 ? 131.460 205.397 146.010 1.00 86.30  ? 242 LEU A HB3  1 
ATOM   3588 H  HG   . LEU A 1 231 ? 131.413 203.995 147.891 1.00 86.89  ? 242 LEU A HG   1 
ATOM   3589 H  HD11 . LEU A 1 231 ? 132.335 201.917 147.914 1.00 86.60  ? 242 LEU A HD11 1 
ATOM   3590 H  HD12 . LEU A 1 231 ? 131.245 201.913 146.761 1.00 86.54  ? 242 LEU A HD12 1 
ATOM   3591 H  HD13 . LEU A 1 231 ? 132.787 202.038 146.400 1.00 86.07  ? 242 LEU A HD13 1 
ATOM   3592 H  HD21 . LEU A 1 231 ? 133.663 204.047 148.311 1.00 86.28  ? 242 LEU A HD21 1 
ATOM   3593 H  HD22 . LEU A 1 231 ? 133.985 204.110 146.757 1.00 85.95  ? 242 LEU A HD22 1 
ATOM   3594 H  HD23 . LEU A 1 231 ? 133.291 205.346 147.475 1.00 86.35  ? 242 LEU A HD23 1 
ATOM   3595 N  N    . LYS A 1 232 ? 128.556 205.631 146.637 1.00 86.81  ? 243 LYS A N    1 
ATOM   3596 C  CA   . LYS A 1 232 ? 127.545 206.002 147.621 1.00 89.26  ? 243 LYS A CA   1 
ATOM   3597 C  C    . LYS A 1 232 ? 126.295 205.148 147.455 1.00 88.93  ? 243 LYS A C    1 
ATOM   3598 O  O    . LYS A 1 232 ? 125.756 204.611 148.431 1.00 89.14  ? 243 LYS A O    1 
ATOM   3599 C  CB   . LYS A 1 232 ? 127.212 207.491 147.484 1.00 87.79  ? 243 LYS A CB   1 
ATOM   3600 C  CG   . LYS A 1 232 ? 125.937 207.938 148.192 1.00 85.26  ? 243 LYS A CG   1 
ATOM   3601 C  CD   . LYS A 1 232 ? 125.595 209.380 147.852 1.00 86.29  ? 243 LYS A CD   1 
ATOM   3602 C  CE   . LYS A 1 232 ? 124.380 209.875 148.624 1.00 90.60  ? 243 LYS A CE   1 
ATOM   3603 N  NZ   . LYS A 1 232 ? 124.436 209.535 150.072 1.00 89.34  ? 243 LYS A NZ   1 
ATOM   3604 H  H    . LYS A 1 232 ? 128.798 206.268 146.113 1.00 88.06  ? 243 LYS A H    1 
ATOM   3605 H  HA   . LYS A 1 232 ? 127.898 205.852 148.512 1.00 88.94  ? 243 LYS A HA   1 
ATOM   3606 H  HB2  . LYS A 1 232 ? 127.947 208.006 147.851 1.00 88.83  ? 243 LYS A HB2  1 
ATOM   3607 H  HB3  . LYS A 1 232 ? 127.111 207.697 146.541 1.00 88.50  ? 243 LYS A HB3  1 
ATOM   3608 H  HG2  . LYS A 1 232 ? 125.188 207.389 147.913 1.00 88.50  ? 243 LYS A HG2  1 
ATOM   3609 H  HG3  . LYS A 1 232 ? 126.068 207.868 149.150 1.00 88.07  ? 243 LYS A HG3  1 
ATOM   3610 H  HD2  . LYS A 1 232 ? 126.346 209.950 148.073 1.00 88.37  ? 243 LYS A HD2  1 
ATOM   3611 H  HD3  . LYS A 1 232 ? 125.396 209.445 146.905 1.00 88.69  ? 243 LYS A HD3  1 
ATOM   3612 H  HE2  . LYS A 1 232 ? 124.326 210.840 148.544 1.00 89.34  ? 243 LYS A HE2  1 
ATOM   3613 H  HE3  . LYS A 1 232 ? 123.582 209.468 148.251 1.00 89.19  ? 243 LYS A HE3  1 
ATOM   3614 H  HZ1  . LYS A 1 232 ? 123.759 209.922 150.501 1.00 89.19  ? 243 LYS A HZ1  1 
ATOM   3615 H  HZ2  . LYS A 1 232 ? 124.379 208.653 150.181 1.00 88.80  ? 243 LYS A HZ2  1 
ATOM   3616 H  HZ3  . LYS A 1 232 ? 125.202 209.822 150.423 1.00 88.49  ? 243 LYS A HZ3  1 
ATOM   3617 N  N    . ASP A 1 233 ? 125.822 205.009 146.215 1.00 96.60  ? 244 ASP A N    1 
ATOM   3618 C  CA   . ASP A 1 233 ? 124.631 204.205 145.958 1.00 96.46  ? 244 ASP A CA   1 
ATOM   3619 C  C    . ASP A 1 233 ? 124.867 202.743 146.316 1.00 96.46  ? 244 ASP A C    1 
ATOM   3620 O  O    . ASP A 1 233 ? 123.990 202.086 146.890 1.00 95.79  ? 244 ASP A O    1 
ATOM   3621 C  CB   . ASP A 1 233 ? 124.218 204.336 144.493 1.00 95.00  ? 244 ASP A CB   1 
ATOM   3622 C  CG   . ASP A 1 233 ? 123.784 205.742 144.132 1.00 96.42  ? 244 ASP A CG   1 
ATOM   3623 O  OD1  . ASP A 1 233 ? 123.001 206.340 144.901 1.00 95.77  ? 244 ASP A OD1  1 
ATOM   3624 O  OD2  . ASP A 1 233 ? 124.226 206.251 143.081 1.00 97.48  ? 244 ASP A OD2  1 
ATOM   3625 H  H    . ASP A 1 233 ? 126.169 205.367 145.514 1.00 95.28  ? 244 ASP A H    1 
ATOM   3626 H  HA   . ASP A 1 233 ? 123.902 204.535 146.507 1.00 95.37  ? 244 ASP A HA   1 
ATOM   3627 H  HB2  . ASP A 1 233 ? 124.972 204.101 143.930 1.00 95.30  ? 244 ASP A HB2  1 
ATOM   3628 H  HB3  . ASP A 1 233 ? 123.474 203.738 144.318 1.00 95.32  ? 244 ASP A HB3  1 
ATOM   3629 N  N    . PHE A 1 234 ? 126.043 202.214 145.974 1.00 97.55  ? 245 PHE A N    1 
ATOM   3630 C  CA   . PHE A 1 234 ? 126.353 200.826 146.292 1.00 96.66  ? 245 PHE A CA   1 
ATOM   3631 C  C    . PHE A 1 234 ? 126.375 200.603 147.797 1.00 96.58  ? 245 PHE A C    1 
ATOM   3632 O  O    . PHE A 1 234 ? 125.847 199.602 148.293 1.00 98.26  ? 245 PHE A O    1 
ATOM   3633 C  CB   . PHE A 1 234 ? 127.696 200.441 145.670 1.00 92.92  ? 245 PHE A CB   1 
ATOM   3634 C  CG   . PHE A 1 234 ? 128.122 199.031 145.963 1.00 96.16  ? 245 PHE A CG   1 
ATOM   3635 C  CD1  . PHE A 1 234 ? 127.296 197.963 145.654 1.00 94.36  ? 245 PHE A CD1  1 
ATOM   3636 C  CD2  . PHE A 1 234 ? 129.351 198.773 146.545 1.00 98.26  ? 245 PHE A CD2  1 
ATOM   3637 C  CE1  . PHE A 1 234 ? 127.688 196.666 145.922 1.00 94.68  ? 245 PHE A CE1  1 
ATOM   3638 C  CE2  . PHE A 1 234 ? 129.747 197.478 146.816 1.00 98.69  ? 245 PHE A CE2  1 
ATOM   3639 C  CZ   . PHE A 1 234 ? 128.915 196.424 146.503 1.00 97.84  ? 245 PHE A CZ   1 
ATOM   3640 H  H    . PHE A 1 234 ? 126.670 202.635 145.561 1.00 95.53  ? 245 PHE A H    1 
ATOM   3641 H  HA   . PHE A 1 234 ? 125.669 200.253 145.912 1.00 95.87  ? 245 PHE A HA   1 
ATOM   3642 H  HB2  . PHE A 1 234 ? 127.632 200.536 144.706 1.00 95.33  ? 245 PHE A HB2  1 
ATOM   3643 H  HB3  . PHE A 1 234 ? 128.381 201.035 146.014 1.00 94.80  ? 245 PHE A HB3  1 
ATOM   3644 H  HD1  . PHE A 1 234 ? 126.468 198.122 145.262 1.00 95.18  ? 245 PHE A HD1  1 
ATOM   3645 H  HD2  . PHE A 1 234 ? 129.916 199.480 146.758 1.00 95.72  ? 245 PHE A HD2  1 
ATOM   3646 H  HE1  . PHE A 1 234 ? 127.125 195.957 145.711 1.00 95.27  ? 245 PHE A HE1  1 
ATOM   3647 H  HE2  . PHE A 1 234 ? 130.575 197.317 147.207 1.00 96.33  ? 245 PHE A HE2  1 
ATOM   3648 H  HZ   . PHE A 1 234 ? 129.181 195.551 146.685 1.00 96.10  ? 245 PHE A HZ   1 
ATOM   3649 N  N    . CYS A 1 235 ? 126.979 201.530 148.543 1.00 99.35  ? 246 CYS A N    1 
ATOM   3650 C  CA   . CYS A 1 235 ? 126.992 201.419 149.996 1.00 101.51 ? 246 CYS A CA   1 
ATOM   3651 C  C    . CYS A 1 235 ? 125.579 201.476 150.557 1.00 103.10 ? 246 CYS A C    1 
ATOM   3652 O  O    . CYS A 1 235 ? 125.221 200.688 151.440 1.00 103.91 ? 246 CYS A O    1 
ATOM   3653 C  CB   . CYS A 1 235 ? 127.849 202.532 150.599 1.00 104.05 ? 246 CYS A CB   1 
ATOM   3654 S  SG   . CYS A 1 235 ? 129.580 202.522 150.077 1.00 110.54 ? 246 CYS A SG   1 
ATOM   3655 H  H    . CYS A 1 235 ? 127.384 202.224 148.233 1.00 100.91 ? 246 CYS A H    1 
ATOM   3656 H  HA   . CYS A 1 235 ? 127.382 200.567 150.246 1.00 101.85 ? 246 CYS A HA   1 
ATOM   3657 H  HB2  . CYS A 1 235 ? 127.470 203.388 150.342 1.00 102.04 ? 246 CYS A HB2  1 
ATOM   3658 H  HB3  . CYS A 1 235 ? 127.833 202.446 151.565 1.00 102.13 ? 246 CYS A HB3  1 
ATOM   3659 H  HG   . CYS A 1 235 ? 130.152 203.434 150.606 1.00 102.00 ? 246 CYS A HG   1 
ATOM   3660 N  N    . LEU A 1 236 ? 124.757 202.397 150.051 1.00 104.40 ? 247 LEU A N    1 
ATOM   3661 C  CA   . LEU A 1 236 ? 123.390 202.510 150.547 1.00 104.75 ? 247 LEU A CA   1 
ATOM   3662 C  C    . LEU A 1 236 ? 122.606 201.231 150.283 1.00 102.16 ? 247 LEU A C    1 
ATOM   3663 O  O    . LEU A 1 236 ? 121.848 200.769 151.144 1.00 96.71  ? 247 LEU A O    1 
ATOM   3664 C  CB   . LEU A 1 236 ? 122.695 203.707 149.896 1.00 105.90 ? 247 LEU A CB   1 
ATOM   3665 C  CG   . LEU A 1 236 ? 122.872 205.061 150.588 1.00 103.94 ? 247 LEU A CG   1 
ATOM   3666 C  CD1  . LEU A 1 236 ? 122.298 206.174 149.726 1.00 103.70 ? 247 LEU A CD1  1 
ATOM   3667 C  CD2  . LEU A 1 236 ? 122.222 205.062 151.964 1.00 99.71  ? 247 LEU A CD2  1 
ATOM   3668 H  H    . LEU A 1 236 ? 124.964 202.957 149.432 1.00 101.63 ? 247 LEU A H    1 
ATOM   3669 H  HA   . LEU A 1 236 ? 123.413 202.654 151.505 1.00 101.65 ? 247 LEU A HA   1 
ATOM   3670 H  HB2  . LEU A 1 236 ? 123.033 203.800 148.992 1.00 102.20 ? 247 LEU A HB2  1 
ATOM   3671 H  HB3  . LEU A 1 236 ? 121.743 203.524 149.865 1.00 102.31 ? 247 LEU A HB3  1 
ATOM   3672 H  HG   . LEU A 1 236 ? 123.820 205.232 150.705 1.00 101.87 ? 247 LEU A HG   1 
ATOM   3673 H  HD11 . LEU A 1 236 ? 122.422 207.022 150.181 1.00 101.96 ? 247 LEU A HD11 1 
ATOM   3674 H  HD12 . LEU A 1 236 ? 122.762 206.184 148.874 1.00 101.68 ? 247 LEU A HD12 1 
ATOM   3675 H  HD13 . LEU A 1 236 ? 121.353 206.008 149.586 1.00 101.82 ? 247 LEU A HD13 1 
ATOM   3676 H  HD21 . LEU A 1 236 ? 122.194 205.972 152.298 1.00 101.41 ? 247 LEU A HD21 1 
ATOM   3677 H  HD22 . LEU A 1 236 ? 121.321 204.711 151.886 1.00 101.47 ? 247 LEU A HD22 1 
ATOM   3678 H  HD23 . LEU A 1 236 ? 122.743 204.505 152.563 1.00 101.21 ? 247 LEU A HD23 1 
ATOM   3679 N  N    . LYS A 1 237 ? 122.776 200.645 149.097 1.00 93.28  ? 248 LYS A N    1 
ATOM   3680 C  CA   . LYS A 1 237 ? 122.029 199.440 148.756 1.00 89.65  ? 248 LYS A CA   1 
ATOM   3681 C  C    . LYS A 1 237 ? 122.519 198.238 149.553 1.00 88.16  ? 248 LYS A C    1 
ATOM   3682 O  O    . LYS A 1 237 ? 121.713 197.416 150.005 1.00 91.30  ? 248 LYS A O    1 
ATOM   3683 C  CB   . LYS A 1 237 ? 122.141 199.167 147.255 1.00 90.06  ? 248 LYS A CB   1 
ATOM   3684 C  CG   . LYS A 1 237 ? 121.056 198.258 146.672 1.00 90.04  ? 248 LYS A CG   1 
ATOM   3685 C  CD   . LYS A 1 237 ? 119.632 198.671 147.053 1.00 89.77  ? 248 LYS A CD   1 
ATOM   3686 C  CE   . LYS A 1 237 ? 119.348 200.140 146.759 1.00 89.02  ? 248 LYS A CE   1 
ATOM   3687 N  NZ   . LYS A 1 237 ? 118.030 200.569 147.301 1.00 89.34  ? 248 LYS A NZ   1 
ATOM   3688 H  H    . LYS A 1 237 ? 123.310 200.922 148.483 1.00 91.59  ? 248 LYS A H    1 
ATOM   3689 H  HA   . LYS A 1 237 ? 121.099 199.586 148.981 1.00 90.68  ? 248 LYS A HA   1 
ATOM   3690 H  HB2  . LYS A 1 237 ? 122.104 200.013 146.781 1.00 90.92  ? 248 LYS A HB2  1 
ATOM   3691 H  HB3  . LYS A 1 237 ? 122.996 198.742 147.085 1.00 90.77  ? 248 LYS A HB3  1 
ATOM   3692 H  HG2  . LYS A 1 237 ? 121.120 198.275 145.704 1.00 90.52  ? 248 LYS A HG2  1 
ATOM   3693 H  HG3  . LYS A 1 237 ? 121.199 197.354 146.995 1.00 90.47  ? 248 LYS A HG3  1 
ATOM   3694 H  HD2  . LYS A 1 237 ? 119.005 198.139 146.538 1.00 90.39  ? 248 LYS A HD2  1 
ATOM   3695 H  HD3  . LYS A 1 237 ? 119.493 198.516 148.000 1.00 90.60  ? 248 LYS A HD3  1 
ATOM   3696 H  HE2  . LYS A 1 237 ? 120.027 200.695 147.171 1.00 90.55  ? 248 LYS A HE2  1 
ATOM   3697 H  HE3  . LYS A 1 237 ? 119.341 200.278 145.799 1.00 90.16  ? 248 LYS A HE3  1 
ATOM   3698 H  HZ1  . LYS A 1 237 ? 117.892 201.429 147.121 1.00 90.34  ? 248 LYS A HZ1  1 
ATOM   3699 H  HZ2  . LYS A 1 237 ? 117.378 200.088 146.932 1.00 90.31  ? 248 LYS A HZ2  1 
ATOM   3700 H  HZ3  . LYS A 1 237 ? 118.011 200.451 148.183 1.00 90.50  ? 248 LYS A HZ3  1 
ATOM   3701 N  N    . ALA A 1 238 ? 123.836 198.114 149.736 1.00 98.28  ? 249 ALA A N    1 
ATOM   3702 C  CA   . ALA A 1 238 ? 124.388 196.946 150.411 1.00 101.96 ? 249 ALA A CA   1 
ATOM   3703 C  C    . ALA A 1 238 ? 124.199 197.006 151.921 1.00 102.42 ? 249 ALA A C    1 
ATOM   3704 O  O    . ALA A 1 238 ? 124.070 195.959 152.563 1.00 106.32 ? 249 ALA A O    1 
ATOM   3705 C  CB   . ALA A 1 238 ? 125.873 196.804 150.078 1.00 101.54 ? 249 ALA A CB   1 
ATOM   3706 H  H    . ALA A 1 238 ? 124.423 198.688 149.481 1.00 100.62 ? 249 ALA A H    1 
ATOM   3707 H  HA   . ALA A 1 238 ? 123.933 196.153 150.086 1.00 101.20 ? 249 ALA A HA   1 
ATOM   3708 H  HB1  . ALA A 1 238 ? 126.233 196.043 150.560 1.00 101.31 ? 249 ALA A HB1  1 
ATOM   3709 H  HB2  . ALA A 1 238 ? 125.971 196.667 149.122 1.00 100.95 ? 249 ALA A HB2  1 
ATOM   3710 H  HB3  . ALA A 1 238 ? 126.334 197.614 150.345 1.00 101.21 ? 249 ALA A HB3  1 
ATOM   3711 N  N    . LEU A 1 239 ? 124.184 198.207 152.503 1.00 104.40 ? 250 LEU A N    1 
ATOM   3712 C  CA   . LEU A 1 239 ? 124.052 198.320 153.951 1.00 109.14 ? 250 LEU A CA   1 
ATOM   3713 C  C    . LEU A 1 239 ? 122.718 197.773 154.440 1.00 109.43 ? 250 LEU A C    1 
ATOM   3714 O  O    . LEU A 1 239 ? 122.626 197.290 155.575 1.00 107.71 ? 250 LEU A O    1 
ATOM   3715 C  CB   . LEU A 1 239 ? 124.215 199.779 154.378 1.00 111.69 ? 250 LEU A CB   1 
ATOM   3716 C  CG   . LEU A 1 239 ? 125.649 200.312 154.365 1.00 112.47 ? 250 LEU A CG   1 
ATOM   3717 C  CD1  . LEU A 1 239 ? 125.654 201.832 154.365 1.00 109.80 ? 250 LEU A CD1  1 
ATOM   3718 C  CD2  . LEU A 1 239 ? 126.436 199.772 155.549 1.00 109.34 ? 250 LEU A CD2  1 
ATOM   3719 H  H    . LEU A 1 239 ? 124.248 198.958 152.088 1.00 107.05 ? 250 LEU A H    1 
ATOM   3720 H  HA   . LEU A 1 239 ? 124.757 197.804 154.372 1.00 108.78 ? 250 LEU A HA   1 
ATOM   3721 H  HB2  . LEU A 1 239 ? 123.692 200.334 153.779 1.00 108.18 ? 250 LEU A HB2  1 
ATOM   3722 H  HB3  . LEU A 1 239 ? 123.878 199.872 155.283 1.00 109.14 ? 250 LEU A HB3  1 
ATOM   3723 H  HG   . LEU A 1 239 ? 126.090 200.011 153.556 1.00 108.92 ? 250 LEU A HG   1 
ATOM   3724 H  HD11 . LEU A 1 239 ? 125.190 202.150 153.575 1.00 108.42 ? 250 LEU A HD11 1 
ATOM   3725 H  HD12 . LEU A 1 239 ? 125.204 202.149 155.164 1.00 108.65 ? 250 LEU A HD12 1 
ATOM   3726 H  HD13 . LEU A 1 239 ? 126.573 202.144 154.357 1.00 108.56 ? 250 LEU A HD13 1 
ATOM   3727 H  HD21 . LEU A 1 239 ? 127.328 200.152 155.534 1.00 108.54 ? 250 LEU A HD21 1 
ATOM   3728 H  HD22 . LEU A 1 239 ? 125.983 200.021 156.370 1.00 108.47 ? 250 LEU A HD22 1 
ATOM   3729 H  HD23 . LEU A 1 239 ? 126.488 198.806 155.480 1.00 108.83 ? 250 LEU A HD23 1 
ATOM   3730 N  N    . GLY A 1 240 ? 121.679 197.839 153.611 1.00 118.69 ? 251 GLY A N    1 
ATOM   3731 C  CA   . GLY A 1 240 ? 120.367 197.366 154.007 1.00 121.20 ? 251 GLY A CA   1 
ATOM   3732 C  C    . GLY A 1 240 ? 119.690 196.505 152.962 1.00 121.15 ? 251 GLY A C    1 
ATOM   3733 O  O    . GLY A 1 240 ? 119.444 196.954 151.838 1.00 120.71 ? 251 GLY A O    1 
ATOM   3734 H  H    . GLY A 1 240 ? 121.713 198.155 152.811 1.00 117.63 ? 251 GLY A H    1 
ATOM   3735 H  HA2  . GLY A 1 240 ? 120.442 196.845 154.822 1.00 119.21 ? 251 GLY A HA2  1 
ATOM   3736 H  HA3  . GLY A 1 240 ? 119.796 198.129 154.187 1.00 119.13 ? 251 GLY A HA3  1 
ATOM   3737 N  N    . GLN A 1 241 ? 119.383 195.260 153.324 1.00 117.87 ? 252 GLN A N    1 
ATOM   3738 C  CA   . GLN A 1 241 ? 118.637 194.355 152.459 1.00 115.70 ? 252 GLN A CA   1 
ATOM   3739 C  C    . GLN A 1 241 ? 117.160 194.281 152.813 1.00 115.70 ? 252 GLN A C    1 
ATOM   3740 O  O    . GLN A 1 241 ? 116.342 193.955 151.946 1.00 118.21 ? 252 GLN A O    1 
ATOM   3741 C  CB   . GLN A 1 241 ? 119.233 192.944 152.524 1.00 113.87 ? 252 GLN A CB   1 
ATOM   3742 C  CG   . GLN A 1 241 ? 120.439 192.741 151.621 1.00 114.45 ? 252 GLN A CG   1 
ATOM   3743 C  CD   . GLN A 1 241 ? 121.648 193.534 152.073 1.00 117.14 ? 252 GLN A CD   1 
ATOM   3744 O  OE1  . GLN A 1 241 ? 122.141 193.356 153.187 1.00 119.92 ? 252 GLN A OE1  1 
ATOM   3745 N  NE2  . GLN A 1 241 ? 122.134 194.415 151.208 1.00 116.56 ? 252 GLN A NE2  1 
ATOM   3746 H  H    . GLN A 1 241 ? 119.602 194.912 154.080 1.00 115.64 ? 252 GLN A H    1 
ATOM   3747 H  HA   . GLN A 1 241 ? 118.707 194.665 151.543 1.00 115.37 ? 252 GLN A HA   1 
ATOM   3748 H  HB2  . GLN A 1 241 ? 119.512 192.765 153.435 1.00 114.97 ? 252 GLN A HB2  1 
ATOM   3749 H  HB3  . GLN A 1 241 ? 118.553 192.307 152.257 1.00 115.25 ? 252 GLN A HB3  1 
ATOM   3750 H  HG2  . GLN A 1 241 ? 120.679 191.801 151.621 1.00 115.39 ? 252 GLN A HG2  1 
ATOM   3751 H  HG3  . GLN A 1 241 ? 120.212 193.025 150.722 1.00 115.27 ? 252 GLN A HG3  1 
ATOM   3752 H  HE21 . GLN A 1 241 ? 121.763 194.512 150.438 1.00 115.13 ? 252 GLN A HE21 1 
ATOM   3753 H  HE22 . GLN A 1 241 ? 122.820 194.890 151.417 1.00 115.13 ? 252 GLN A HE22 1 
ATOM   3754 N  N    . GLU A 1 242 ? 116.804 194.576 154.059 1.00 88.22  ? 253 GLU A N    1 
ATOM   3755 C  CA   . GLU A 1 242 ? 115.421 194.580 154.514 1.00 87.89  ? 253 GLU A CA   1 
ATOM   3756 C  C    . GLU A 1 242 ? 114.980 196.015 154.755 1.00 89.00  ? 253 GLU A C    1 
ATOM   3757 O  O    . GLU A 1 242 ? 115.682 196.780 155.424 1.00 92.25  ? 253 GLU A O    1 
ATOM   3758 C  CB   . GLU A 1 242 ? 115.266 193.757 155.793 1.00 88.07  ? 253 GLU A CB   1 
ATOM   3759 H  H    . GLU A 1 242 ? 117.363 194.785 154.676 1.00 90.97  ? 253 GLU A H    1 
ATOM   3760 H  HA   . GLU A 1 242 ? 114.852 194.194 153.830 1.00 91.51  ? 253 GLU A HA   1 
ATOM   3761 N  N    . ALA A 1 243 ? 113.818 196.378 154.208 1.00 106.95 ? 254 ALA A N    1 
ATOM   3762 C  CA   . ALA A 1 243 ? 113.302 197.726 154.417 1.00 109.96 ? 254 ALA A CA   1 
ATOM   3763 C  C    . ALA A 1 243 ? 113.077 197.997 155.898 1.00 111.24 ? 254 ALA A C    1 
ATOM   3764 O  O    . ALA A 1 243 ? 113.410 199.078 156.398 1.00 109.84 ? 254 ALA A O    1 
ATOM   3765 C  CB   . ALA A 1 243 ? 112.006 197.922 153.631 1.00 109.35 ? 254 ALA A CB   1 
ATOM   3766 H  H    . ALA A 1 243 ? 113.320 195.873 153.723 1.00 108.92 ? 254 ALA A H    1 
ATOM   3767 H  HA   . ALA A 1 243 ? 113.952 198.368 154.090 1.00 109.18 ? 254 ALA A HA   1 
ATOM   3768 H  HB1  . ALA A 1 243 ? 111.676 198.821 153.787 1.00 109.62 ? 254 ALA A HB1  1 
ATOM   3769 H  HB2  . ALA A 1 243 ? 112.187 197.794 152.687 1.00 109.08 ? 254 ALA A HB2  1 
ATOM   3770 H  HB3  . ALA A 1 243 ? 111.352 197.272 153.935 1.00 109.27 ? 254 ALA A HB3  1 
ATOM   3771 N  N    . ASP A 1 244 ? 112.511 197.025 156.616 1.00 129.34 ? 255 ASP A N    1 
ATOM   3772 C  CA   . ASP A 1 244 ? 112.374 197.165 158.061 1.00 131.29 ? 255 ASP A CA   1 
ATOM   3773 C  C    . ASP A 1 244 ? 113.739 197.220 158.733 1.00 130.26 ? 255 ASP A C    1 
ATOM   3774 O  O    . ASP A 1 244 ? 113.945 197.987 159.681 1.00 130.32 ? 255 ASP A O    1 
ATOM   3775 C  CB   . ASP A 1 244 ? 111.545 196.010 158.623 1.00 130.82 ? 255 ASP A CB   1 
ATOM   3776 C  CG   . ASP A 1 244 ? 110.117 196.015 158.113 1.00 129.70 ? 255 ASP A CG   1 
ATOM   3777 O  OD1  . ASP A 1 244 ? 109.775 196.907 157.309 1.00 130.10 ? 255 ASP A OD1  1 
ATOM   3778 O  OD2  . ASP A 1 244 ? 109.338 195.127 158.516 1.00 130.47 ? 255 ASP A OD2  1 
ATOM   3779 H  H    . ASP A 1 244 ? 112.203 196.289 156.295 1.00 128.83 ? 255 ASP A H    1 
ATOM   3780 H  HA   . ASP A 1 244 ? 111.908 197.993 158.257 1.00 129.83 ? 255 ASP A HA   1 
ATOM   3781 H  HB2  . ASP A 1 244 ? 111.955 195.171 158.362 1.00 129.66 ? 255 ASP A HB2  1 
ATOM   3782 H  HB3  . ASP A 1 244 ? 111.519 196.081 159.590 1.00 130.00 ? 255 ASP A HB3  1 
ATOM   3783 N  N    . LYS A 1 245 ? 114.687 196.410 158.255 1.00 124.60 ? 256 LYS A N    1 
ATOM   3784 C  CA   . LYS A 1 245 ? 116.027 196.417 158.833 1.00 125.25 ? 256 LYS A CA   1 
ATOM   3785 C  C    . LYS A 1 245 ? 116.698 197.773 158.654 1.00 124.81 ? 256 LYS A C    1 
ATOM   3786 O  O    . LYS A 1 245 ? 117.339 198.283 159.581 1.00 121.69 ? 256 LYS A O    1 
ATOM   3787 C  CB   . LYS A 1 245 ? 116.874 195.315 158.196 1.00 124.46 ? 256 LYS A CB   1 
ATOM   3788 C  CG   . LYS A 1 245 ? 118.220 195.093 158.874 1.00 123.89 ? 256 LYS A CG   1 
ATOM   3789 C  CD   . LYS A 1 245 ? 119.105 194.141 158.078 1.00 123.68 ? 256 LYS A CD   1 
ATOM   3790 C  CE   . LYS A 1 245 ? 119.557 194.759 156.764 1.00 122.96 ? 256 LYS A CE   1 
ATOM   3791 N  NZ   . LYS A 1 245 ? 120.766 194.087 156.212 1.00 121.09 ? 256 LYS A NZ   1 
ATOM   3792 H  H    . LYS A 1 245 ? 114.579 195.857 157.606 1.00 121.75 ? 256 LYS A H    1 
ATOM   3793 H  HA   . LYS A 1 245 ? 115.963 196.236 159.783 1.00 122.58 ? 256 LYS A HA   1 
ATOM   3794 H  HB2  . LYS A 1 245 ? 116.382 194.480 158.240 1.00 122.03 ? 256 LYS A HB2  1 
ATOM   3795 H  HB3  . LYS A 1 245 ? 117.039 195.549 157.270 1.00 121.56 ? 256 LYS A HB3  1 
ATOM   3796 H  HG2  . LYS A 1 245 ? 118.684 195.941 158.952 1.00 122.44 ? 256 LYS A HG2  1 
ATOM   3797 H  HG3  . LYS A 1 245 ? 118.075 194.708 159.752 1.00 122.27 ? 256 LYS A HG3  1 
ATOM   3798 H  HD2  . LYS A 1 245 ? 119.894 193.926 158.600 1.00 122.26 ? 256 LYS A HD2  1 
ATOM   3799 H  HD3  . LYS A 1 245 ? 118.606 193.334 157.878 1.00 121.98 ? 256 LYS A HD3  1 
ATOM   3800 H  HE2  . LYS A 1 245 ? 118.844 194.676 156.112 1.00 121.00 ? 256 LYS A HE2  1 
ATOM   3801 H  HE3  . LYS A 1 245 ? 119.771 195.694 156.908 1.00 122.36 ? 256 LYS A HE3  1 
ATOM   3802 H  HZ1  . LYS A 1 245 ? 121.018 194.486 155.457 1.00 121.77 ? 256 LYS A HZ1  1 
ATOM   3803 H  HZ2  . LYS A 1 245 ? 121.433 194.131 156.799 1.00 121.81 ? 256 LYS A HZ2  1 
ATOM   3804 H  HZ3  . LYS A 1 245 ? 120.587 193.232 156.041 1.00 121.46 ? 256 LYS A HZ3  1 
ATOM   3805 N  N    . GLY A 1 246 ? 116.564 198.371 157.472 1.00 126.10 ? 257 GLY A N    1 
ATOM   3806 C  CA   . GLY A 1 246 ? 117.242 199.625 157.218 1.00 123.40 ? 257 GLY A CA   1 
ATOM   3807 C  C    . GLY A 1 246 ? 118.749 199.425 157.156 1.00 120.75 ? 257 GLY A C    1 
ATOM   3808 O  O    . GLY A 1 246 ? 119.257 198.337 156.872 1.00 121.08 ? 257 GLY A O    1 
ATOM   3809 H  H    . GLY A 1 246 ? 116.094 198.074 156.817 1.00 122.12 ? 257 GLY A H    1 
ATOM   3810 H  HA2  . GLY A 1 246 ? 116.941 199.994 156.373 1.00 122.34 ? 257 GLY A HA2  1 
ATOM   3811 H  HA3  . GLY A 1 246 ? 117.039 200.257 157.925 1.00 122.45 ? 257 GLY A HA3  1 
ATOM   3812 N  N    . LEU A 1 247 ? 119.470 200.510 157.428 1.00 105.60 ? 258 LEU A N    1 
ATOM   3813 C  CA   . LEU A 1 247 ? 120.923 200.434 157.486 1.00 105.19 ? 258 LEU A CA   1 
ATOM   3814 C  C    . LEU A 1 247 ? 121.340 199.459 158.578 1.00 103.81 ? 258 LEU A C    1 
ATOM   3815 O  O    . LEU A 1 247 ? 120.866 199.541 159.714 1.00 105.22 ? 258 LEU A O    1 
ATOM   3816 C  CB   . LEU A 1 247 ? 121.515 201.819 157.750 1.00 107.32 ? 258 LEU A CB   1 
ATOM   3817 C  CG   . LEU A 1 247 ? 122.963 202.035 157.302 1.00 104.91 ? 258 LEU A CG   1 
ATOM   3818 C  CD1  . LEU A 1 247 ? 123.316 203.513 157.334 1.00 106.42 ? 258 LEU A CD1  1 
ATOM   3819 C  CD2  . LEU A 1 247 ? 123.928 201.234 158.162 1.00 103.92 ? 258 LEU A CD2  1 
ATOM   3820 H  H    . LEU A 1 247 ? 119.146 201.292 157.580 1.00 106.24 ? 258 LEU A H    1 
ATOM   3821 H  HA   . LEU A 1 247 ? 121.265 200.110 156.637 1.00 105.99 ? 258 LEU A HA   1 
ATOM   3822 H  HB2  . LEU A 1 247 ? 120.969 202.474 157.288 1.00 106.30 ? 258 LEU A HB2  1 
ATOM   3823 H  HB3  . LEU A 1 247 ? 121.480 201.987 158.704 1.00 106.06 ? 258 LEU A HB3  1 
ATOM   3824 H  HG   . LEU A 1 247 ? 123.056 201.728 156.386 1.00 105.66 ? 258 LEU A HG   1 
ATOM   3825 H  HD11 . LEU A 1 247 ? 124.141 203.651 156.842 1.00 105.71 ? 258 LEU A HD11 1 
ATOM   3826 H  HD12 . LEU A 1 247 ? 122.598 204.018 156.923 1.00 105.87 ? 258 LEU A HD12 1 
ATOM   3827 H  HD13 . LEU A 1 247 ? 123.429 203.790 158.257 1.00 106.05 ? 258 LEU A HD13 1 
ATOM   3828 H  HD21 . LEU A 1 247 ? 124.798 201.663 158.146 1.00 105.32 ? 258 LEU A HD21 1 
ATOM   3829 H  HD22 . LEU A 1 247 ? 123.592 201.203 159.071 1.00 105.53 ? 258 LEU A HD22 1 
ATOM   3830 H  HD23 . LEU A 1 247 ? 123.997 200.335 157.805 1.00 105.46 ? 258 LEU A HD23 1 
ATOM   3831 N  N    . SER A 1 248 ? 122.231 198.535 158.232 1.00 102.16 ? 259 SER A N    1 
ATOM   3832 C  CA   . SER A 1 248 ? 122.640 197.491 159.161 1.00 105.63 ? 259 SER A CA   1 
ATOM   3833 C  C    . SER A 1 248 ? 124.018 196.992 158.757 1.00 106.23 ? 259 SER A C    1 
ATOM   3834 O  O    . SER A 1 248 ? 124.509 197.273 157.661 1.00 103.48 ? 259 SER A O    1 
ATOM   3835 C  CB   . SER A 1 248 ? 121.627 196.342 159.188 1.00 106.95 ? 259 SER A CB   1 
ATOM   3836 H  H    . SER A 1 248 ? 122.614 198.492 157.463 1.00 105.32 ? 259 SER A H    1 
ATOM   3837 H  HA   . SER A 1 248 ? 122.701 197.863 160.054 1.00 105.72 ? 259 SER A HA   1 
ATOM   3838 N  N    . GLY A 1 249 ? 124.637 196.243 159.666 1.00 118.37 ? 260 GLY A N    1 
ATOM   3839 C  CA   . GLY A 1 249 ? 125.956 195.706 159.409 1.00 118.15 ? 260 GLY A CA   1 
ATOM   3840 C  C    . GLY A 1 249 ? 126.972 196.809 159.187 1.00 119.31 ? 260 GLY A C    1 
ATOM   3841 O  O    . GLY A 1 249 ? 126.915 197.885 159.792 1.00 120.34 ? 260 GLY A O    1 
ATOM   3842 H  H    . GLY A 1 249 ? 124.312 196.035 160.434 1.00 117.52 ? 260 GLY A H    1 
ATOM   3843 H  HA2  . GLY A 1 249 ? 126.241 195.168 160.164 1.00 117.59 ? 260 GLY A HA2  1 
ATOM   3844 H  HA3  . GLY A 1 249 ? 125.931 195.146 158.619 1.00 117.70 ? 260 GLY A HA3  1 
ATOM   3845 N  N    . CYS A 1 250 ? 127.922 196.536 158.298 1.00 96.84  ? 261 CYS A N    1 
ATOM   3846 C  CA   . CYS A 1 250 ? 128.962 197.504 157.985 1.00 91.87  ? 261 CYS A CA   1 
ATOM   3847 C  C    . CYS A 1 250 ? 129.766 196.996 156.801 1.00 89.04  ? 261 CYS A C    1 
ATOM   3848 O  O    . CYS A 1 250 ? 129.889 195.786 156.592 1.00 87.17  ? 261 CYS A O    1 
ATOM   3849 C  CB   . CYS A 1 250 ? 129.882 197.748 159.187 1.00 98.53  ? 261 CYS A CB   1 
ATOM   3850 H  H    . CYS A 1 250 ? 127.986 195.796 157.865 1.00 94.75  ? 261 CYS A H    1 
ATOM   3851 H  HA   . CYS A 1 250 ? 128.549 198.345 157.736 1.00 94.10  ? 261 CYS A HA   1 
ATOM   3852 N  N    . GLY A 1 251 ? 130.311 197.937 156.031 1.00 100.36 ? 262 GLY A N    1 
ATOM   3853 C  CA   . GLY A 1 251 ? 131.136 197.629 154.887 1.00 106.58 ? 262 GLY A CA   1 
ATOM   3854 C  C    . GLY A 1 251 ? 132.556 198.144 155.057 1.00 105.60 ? 262 GLY A C    1 
ATOM   3855 O  O    . GLY A 1 251 ? 132.896 198.812 156.037 1.00 103.61 ? 262 GLY A O    1 
ATOM   3856 H  H    . GLY A 1 251 ? 130.210 198.781 156.163 1.00 102.87 ? 262 GLY A H    1 
ATOM   3857 H  HA2  . GLY A 1 251 ? 131.169 196.669 154.754 1.00 104.11 ? 262 GLY A HA2  1 
ATOM   3858 H  HA3  . GLY A 1 251 ? 130.755 198.037 154.094 1.00 104.00 ? 262 GLY A HA3  1 
ATOM   3859 N  N    . ILE A 1 252 ? 133.381 197.811 154.069 1.00 98.42  ? 263 ILE A N    1 
ATOM   3860 C  CA   . ILE A 1 252 ? 134.775 198.234 154.021 1.00 98.45  ? 263 ILE A CA   1 
ATOM   3861 C  C    . ILE A 1 252 ? 135.061 198.809 152.642 1.00 94.77  ? 263 ILE A C    1 
ATOM   3862 O  O    . ILE A 1 252 ? 134.491 198.360 151.642 1.00 96.53  ? 263 ILE A O    1 
ATOM   3863 C  CB   . ILE A 1 252 ? 135.742 197.072 154.336 1.00 100.81 ? 263 ILE A CB   1 
ATOM   3864 C  CG1  . ILE A 1 252 ? 135.491 196.533 155.747 1.00 100.90 ? 263 ILE A CG1  1 
ATOM   3865 C  CG2  . ILE A 1 252 ? 137.190 197.523 154.191 1.00 100.88 ? 263 ILE A CG2  1 
ATOM   3866 C  CD1  . ILE A 1 252 ? 134.536 195.368 155.793 1.00 99.96  ? 263 ILE A CD1  1 
ATOM   3867 H  H    . ILE A 1 252 ? 133.149 197.327 153.397 1.00 98.27  ? 263 ILE A H    1 
ATOM   3868 H  HA   . ILE A 1 252 ? 134.921 198.934 154.676 1.00 98.78  ? 263 ILE A HA   1 
ATOM   3869 H  HB   . ILE A 1 252 ? 135.579 196.357 153.701 1.00 98.33  ? 263 ILE A HB   1 
ATOM   3870 H  HG12 . ILE A 1 252 ? 136.333 196.239 156.127 1.00 98.08  ? 263 ILE A HG12 1 
ATOM   3871 H  HG13 . ILE A 1 252 ? 135.116 197.244 156.290 1.00 98.63  ? 263 ILE A HG13 1 
ATOM   3872 H  HG21 . ILE A 1 252 ? 137.773 196.834 154.547 1.00 98.24  ? 263 ILE A HG21 1 
ATOM   3873 H  HG22 . ILE A 1 252 ? 137.388 197.665 153.253 1.00 98.53  ? 263 ILE A HG22 1 
ATOM   3874 H  HG23 . ILE A 1 252 ? 137.315 198.348 154.686 1.00 98.67  ? 263 ILE A HG23 1 
ATOM   3875 H  HD11 . ILE A 1 252 ? 134.535 194.997 156.690 1.00 98.44  ? 263 ILE A HD11 1 
ATOM   3876 H  HD12 . ILE A 1 252 ? 133.647 195.677 155.562 1.00 98.74  ? 263 ILE A HD12 1 
ATOM   3877 H  HD13 . ILE A 1 252 ? 134.830 194.695 155.159 1.00 97.96  ? 263 ILE A HD13 1 
ATOM   3878 N  N    . VAL A 1 253 ? 135.927 199.817 152.596 1.00 82.93  ? 264 VAL A N    1 
ATOM   3879 C  CA   . VAL A 1 253 ? 136.386 200.417 151.350 1.00 81.47  ? 264 VAL A CA   1 
ATOM   3880 C  C    . VAL A 1 253 ? 137.906 200.440 151.378 1.00 80.11  ? 264 VAL A C    1 
ATOM   3881 O  O    . VAL A 1 253 ? 138.505 200.861 152.374 1.00 83.55  ? 264 VAL A O    1 
ATOM   3882 C  CB   . VAL A 1 253 ? 135.822 201.837 151.151 1.00 83.76  ? 264 VAL A CB   1 
ATOM   3883 C  CG1  . VAL A 1 253 ? 136.307 202.423 149.834 1.00 80.35  ? 264 VAL A CG1  1 
ATOM   3884 C  CG2  . VAL A 1 253 ? 134.302 201.815 151.204 1.00 87.12  ? 264 VAL A CG2  1 
ATOM   3885 H  H    . VAL A 1 253 ? 136.272 200.180 153.295 1.00 84.43  ? 264 VAL A H    1 
ATOM   3886 H  HA   . VAL A 1 253 ? 136.102 199.869 150.602 1.00 84.24  ? 264 VAL A HA   1 
ATOM   3887 H  HB   . VAL A 1 253 ? 136.140 202.406 151.868 1.00 83.87  ? 264 VAL A HB   1 
ATOM   3888 H  HG11 . VAL A 1 253 ? 135.815 203.239 149.654 1.00 83.37  ? 264 VAL A HG11 1 
ATOM   3889 H  HG12 . VAL A 1 253 ? 137.255 202.618 149.902 1.00 83.29  ? 264 VAL A HG12 1 
ATOM   3890 H  HG13 . VAL A 1 253 ? 136.149 201.780 149.126 1.00 83.31  ? 264 VAL A HG13 1 
ATOM   3891 H  HG21 . VAL A 1 253 ? 133.968 202.709 151.031 1.00 84.25  ? 264 VAL A HG21 1 
ATOM   3892 H  HG22 . VAL A 1 253 ? 133.972 201.202 150.528 1.00 84.15  ? 264 VAL A HG22 1 
ATOM   3893 H  HG23 . VAL A 1 253 ? 134.020 201.521 152.084 1.00 85.06  ? 264 VAL A HG23 1 
ATOM   3894 N  N    . TYR A 1 254 ? 138.526 199.988 150.294 1.00 74.97  ? 265 TYR A N    1 
ATOM   3895 C  CA   . TYR A 1 254 ? 139.973 199.869 150.219 1.00 73.77  ? 265 TYR A CA   1 
ATOM   3896 C  C    . TYR A 1 254 ? 140.559 200.960 149.330 1.00 72.86  ? 265 TYR A C    1 
ATOM   3897 O  O    . TYR A 1 254 ? 139.964 201.359 148.327 1.00 70.55  ? 265 TYR A O    1 
ATOM   3898 C  CB   . TYR A 1 254 ? 140.372 198.491 149.693 1.00 71.15  ? 265 TYR A CB   1 
ATOM   3899 C  CG   . TYR A 1 254 ? 140.469 197.449 150.781 1.00 66.05  ? 265 TYR A CG   1 
ATOM   3900 C  CD1  . TYR A 1 254 ? 141.656 197.242 151.466 1.00 72.24  ? 265 TYR A CD1  1 
ATOM   3901 C  CD2  . TYR A 1 254 ? 139.368 196.682 151.133 1.00 68.89  ? 265 TYR A CD2  1 
ATOM   3902 C  CE1  . TYR A 1 254 ? 141.747 196.294 152.465 1.00 77.82  ? 265 TYR A CE1  1 
ATOM   3903 C  CE2  . TYR A 1 254 ? 139.448 195.734 152.131 1.00 71.75  ? 265 TYR A CE2  1 
ATOM   3904 C  CZ   . TYR A 1 254 ? 140.640 195.543 152.794 1.00 75.84  ? 265 TYR A CZ   1 
ATOM   3905 O  OH   . TYR A 1 254 ? 140.725 194.596 153.789 1.00 78.92  ? 265 TYR A OH   1 
ATOM   3906 H  H    . TYR A 1 254 ? 138.121 199.739 149.577 1.00 75.65  ? 265 TYR A H    1 
ATOM   3907 H  HA   . TYR A 1 254 ? 140.349 199.967 151.107 1.00 74.31  ? 265 TYR A HA   1 
ATOM   3908 H  HB2  . TYR A 1 254 ? 139.707 198.193 149.053 1.00 74.54  ? 265 TYR A HB2  1 
ATOM   3909 H  HB3  . TYR A 1 254 ? 141.239 198.556 149.264 1.00 74.17  ? 265 TYR A HB3  1 
ATOM   3910 H  HD1  . TYR A 1 254 ? 142.404 197.748 151.246 1.00 74.14  ? 265 TYR A HD1  1 
ATOM   3911 H  HD2  . TYR A 1 254 ? 138.561 196.808 150.687 1.00 74.60  ? 265 TYR A HD2  1 
ATOM   3912 H  HE1  . TYR A 1 254 ? 142.551 196.164 152.915 1.00 75.11  ? 265 TYR A HE1  1 
ATOM   3913 H  HE2  . TYR A 1 254 ? 138.702 195.225 152.353 1.00 74.35  ? 265 TYR A HE2  1 
ATOM   3914 H  HH   . TYR A 1 254 ? 141.507 194.571 154.095 1.00 74.81  ? 265 TYR A HH   1 
ATOM   3915 N  N    . CYS A 1 255 ? 141.740 201.440 149.717 1.00 98.38  ? 266 CYS A N    1 
ATOM   3916 C  CA   . CYS A 1 255 ? 142.421 202.524 149.024 1.00 98.67  ? 266 CYS A CA   1 
ATOM   3917 C  C    . CYS A 1 255 ? 143.808 202.060 148.608 1.00 101.47 ? 266 CYS A C    1 
ATOM   3918 O  O    . CYS A 1 255 ? 144.478 201.336 149.351 1.00 103.09 ? 266 CYS A O    1 
ATOM   3919 C  CB   . CYS A 1 255 ? 142.556 203.766 149.914 1.00 103.71 ? 266 CYS A CB   1 
ATOM   3920 S  SG   . CYS A 1 255 ? 141.020 204.373 150.643 1.00 119.86 ? 266 CYS A SG   1 
ATOM   3921 H  H    . CYS A 1 255 ? 142.175 201.145 150.398 1.00 101.30 ? 266 CYS A H    1 
ATOM   3922 H  HA   . CYS A 1 255 ? 141.926 202.767 148.227 1.00 100.72 ? 266 CYS A HA   1 
ATOM   3923 H  HB2  . CYS A 1 255 ? 143.164 203.565 150.641 1.00 102.29 ? 266 CYS A HB2  1 
ATOM   3924 H  HB3  . CYS A 1 255 ? 142.924 204.485 149.378 1.00 102.42 ? 266 CYS A HB3  1 
ATOM   3925 N  N    . ARG A 1 256 ? 144.238 202.481 147.417 1.00 86.45  ? 267 ARG A N    1 
ATOM   3926 C  CA   . ARG A 1 256 ? 145.595 202.174 146.978 1.00 81.92  ? 267 ARG A CA   1 
ATOM   3927 C  C    . ARG A 1 256 ? 146.620 203.026 147.718 1.00 82.08  ? 267 ARG A C    1 
ATOM   3928 O  O    . ARG A 1 256 ? 147.667 202.521 148.138 1.00 81.63  ? 267 ARG A O    1 
ATOM   3929 C  CB   . ARG A 1 256 ? 145.718 202.380 145.469 1.00 82.26  ? 267 ARG A CB   1 
ATOM   3930 H  H    . ARG A 1 256 ? 143.772 202.936 146.856 1.00 84.80  ? 267 ARG A H    1 
ATOM   3931 H  HA   . ARG A 1 256 ? 145.786 201.242 147.170 1.00 83.74  ? 267 ARG A HA   1 
ATOM   3932 N  N    . THR A 1 257 ? 146.335 204.314 147.889 1.00 100.19 ? 268 THR A N    1 
ATOM   3933 C  CA   . THR A 1 257 ? 147.253 205.258 148.514 1.00 104.60 ? 268 THR A CA   1 
ATOM   3934 C  C    . THR A 1 257 ? 146.671 205.743 149.834 1.00 105.80 ? 268 THR A C    1 
ATOM   3935 O  O    . THR A 1 257 ? 145.483 206.074 149.909 1.00 104.29 ? 268 THR A O    1 
ATOM   3936 C  CB   . THR A 1 257 ? 147.526 206.449 147.592 1.00 104.33 ? 268 THR A CB   1 
ATOM   3937 O  OG1  . THR A 1 257 ? 148.066 205.983 146.349 1.00 103.19 ? 268 THR A OG1  1 
ATOM   3938 C  CG2  . THR A 1 257 ? 148.509 207.416 148.241 1.00 101.42 ? 268 THR A CG2  1 
ATOM   3939 H  H    . THR A 1 257 ? 145.593 204.674 147.644 1.00 101.46 ? 268 THR A H    1 
ATOM   3940 H  HA   . THR A 1 257 ? 148.097 204.816 148.698 1.00 102.19 ? 268 THR A HA   1 
ATOM   3941 H  HB   . THR A 1 257 ? 146.696 206.923 147.425 1.00 102.65 ? 268 THR A HB   1 
ATOM   3942 H  HG1  . THR A 1 257 ? 147.525 205.456 145.981 1.00 102.24 ? 268 THR A HG1  1 
ATOM   3943 H  HG21 . THR A 1 257 ? 148.831 208.050 147.581 1.00 102.19 ? 268 THR A HG21 1 
ATOM   3944 H  HG22 . THR A 1 257 ? 148.074 207.903 148.958 1.00 101.97 ? 268 THR A HG22 1 
ATOM   3945 H  HG23 . THR A 1 257 ? 149.265 206.928 148.603 1.00 102.04 ? 268 THR A HG23 1 
ATOM   3946 N  N    . ARG A 1 258 ? 147.512 205.782 150.869 1.00 108.52 ? 269 ARG A N    1 
ATOM   3947 C  CA   . ARG A 1 258 ? 147.047 206.201 152.188 1.00 108.31 ? 269 ARG A CA   1 
ATOM   3948 C  C    . ARG A 1 258 ? 146.598 207.658 152.187 1.00 108.70 ? 269 ARG A C    1 
ATOM   3949 O  O    . ARG A 1 258 ? 145.558 207.994 152.766 1.00 109.32 ? 269 ARG A O    1 
ATOM   3950 C  CB   . ARG A 1 258 ? 148.153 205.986 153.220 1.00 107.12 ? 269 ARG A CB   1 
ATOM   3951 H  H    . ARG A 1 258 ? 148.346 205.575 150.834 1.00 107.37 ? 269 ARG A H    1 
ATOM   3952 H  HA   . ARG A 1 258 ? 146.288 205.653 152.444 1.00 108.00 ? 269 ARG A HA   1 
ATOM   3953 N  N    . GLU A 1 259 ? 147.369 208.539 151.546 1.00 103.62 ? 270 GLU A N    1 
ATOM   3954 C  CA   . GLU A 1 259 ? 147.085 209.969 151.633 1.00 106.43 ? 270 GLU A CA   1 
ATOM   3955 C  C    . GLU A 1 259 ? 145.749 210.311 150.984 1.00 102.58 ? 270 GLU A C    1 
ATOM   3956 O  O    . GLU A 1 259 ? 144.917 211.004 151.582 1.00 99.46  ? 270 GLU A O    1 
ATOM   3957 C  CB   . GLU A 1 259 ? 148.208 210.777 150.979 1.00 30.00  ? 270 GLU A CB   1 
ATOM   3958 H  H    . GLU A 1 259 ? 148.051 208.337 151.064 1.00 103.78 ? 270 GLU A H    1 
ATOM   3959 H  HA   . GLU A 1 259 ? 147.036 210.222 152.568 1.00 104.76 ? 270 GLU A HA   1 
ATOM   3960 N  N    . ALA A 1 260 ? 145.524 209.840 149.756 1.00 90.50  ? 271 ALA A N    1 
ATOM   3961 C  CA   . ALA A 1 260 ? 144.257 210.103 149.085 1.00 91.03  ? 271 ALA A CA   1 
ATOM   3962 C  C    . ALA A 1 260 ? 143.094 209.407 149.774 1.00 88.11  ? 271 ALA A C    1 
ATOM   3963 O  O    . ALA A 1 260 ? 141.938 209.788 149.556 1.00 91.47  ? 271 ALA A O    1 
ATOM   3964 C  CB   . ALA A 1 260 ? 144.332 209.659 147.624 1.00 91.49  ? 271 ALA A CB   1 
ATOM   3965 H  H    . ALA A 1 260 ? 146.082 209.371 149.299 1.00 92.25  ? 271 ALA A H    1 
ATOM   3966 H  HA   . ALA A 1 260 ? 144.086 211.057 149.099 1.00 91.60  ? 271 ALA A HA   1 
ATOM   3967 H  HB1  . ALA A 1 260 ? 143.481 209.840 147.195 1.00 91.23  ? 271 ALA A HB1  1 
ATOM   3968 H  HB2  . ALA A 1 260 ? 145.039 210.152 147.180 1.00 91.71  ? 271 ALA A HB2  1 
ATOM   3969 H  HB3  . ALA A 1 260 ? 144.521 208.708 147.593 1.00 91.64  ? 271 ALA A HB3  1 
ATOM   3970 N  N    . CYS A 1 261 ? 143.374 208.399 150.598 1.00 93.90  ? 272 CYS A N    1 
ATOM   3971 C  CA   . CYS A 1 261 ? 142.301 207.651 151.237 1.00 100.68 ? 272 CYS A CA   1 
ATOM   3972 C  C    . CYS A 1 261 ? 141.558 208.507 152.257 1.00 105.32 ? 272 CYS A C    1 
ATOM   3973 O  O    . CYS A 1 261 ? 140.345 208.350 152.427 1.00 104.36 ? 272 CYS A O    1 
ATOM   3974 C  CB   . CYS A 1 261 ? 142.872 206.395 151.892 1.00 102.11 ? 272 CYS A CB   1 
ATOM   3975 S  SG   . CYS A 1 261 ? 141.632 205.200 152.397 1.00 107.46 ? 272 CYS A SG   1 
ATOM   3976 H  H    . CYS A 1 261 ? 144.166 208.132 150.801 1.00 101.12 ? 272 CYS A H    1 
ATOM   3977 H  HA   . CYS A 1 261 ? 141.664 207.372 150.561 1.00 101.81 ? 272 CYS A HA   1 
ATOM   3978 H  HB2  . CYS A 1 261 ? 143.463 205.958 151.261 1.00 101.92 ? 272 CYS A HB2  1 
ATOM   3979 H  HB3  . CYS A 1 261 ? 143.371 206.654 152.682 1.00 102.04 ? 272 CYS A HB3  1 
ATOM   3980 N  N    . GLU A 1 262 ? 142.260 209.416 152.939 1.00 118.16 ? 273 GLU A N    1 
ATOM   3981 C  CA   . GLU A 1 262 ? 141.586 210.333 153.856 1.00 119.66 ? 273 GLU A CA   1 
ATOM   3982 C  C    . GLU A 1 262 ? 140.640 211.264 153.105 1.00 117.12 ? 273 GLU A C    1 
ATOM   3983 O  O    . GLU A 1 262 ? 139.512 211.512 153.555 1.00 120.34 ? 273 GLU A O    1 
ATOM   3984 C  CB   . GLU A 1 262 ? 142.626 211.133 154.645 1.00 118.24 ? 273 GLU A CB   1 
ATOM   3985 C  CG   . GLU A 1 262 ? 142.128 212.463 155.202 1.00 118.42 ? 273 GLU A CG   1 
ATOM   3986 C  CD   . GLU A 1 262 ? 140.890 212.309 156.065 1.00 119.86 ? 273 GLU A CD   1 
ATOM   3987 O  OE1  . GLU A 1 262 ? 140.900 211.452 156.974 1.00 120.05 ? 273 GLU A OE1  1 
ATOM   3988 O  OE2  . GLU A 1 262 ? 139.907 213.043 155.832 1.00 119.57 ? 273 GLU A OE2  1 
ATOM   3989 H  H    . GLU A 1 262 ? 143.112 209.520 152.889 1.00 116.74 ? 273 GLU A H    1 
ATOM   3990 H  HA   . GLU A 1 262 ? 141.061 209.820 154.489 1.00 118.17 ? 273 GLU A HA   1 
ATOM   3991 H  HB2  . GLU A 1 262 ? 142.923 210.596 155.395 1.00 117.67 ? 273 GLU A HB2  1 
ATOM   3992 H  HB3  . GLU A 1 262 ? 143.378 211.322 154.063 1.00 117.56 ? 273 GLU A HB3  1 
ATOM   3993 H  HG2  . GLU A 1 262 ? 142.826 212.848 155.755 1.00 117.81 ? 273 GLU A HG2  1 
ATOM   3994 H  HG3  . GLU A 1 262 ? 141.920 213.066 154.472 1.00 117.97 ? 273 GLU A HG3  1 
ATOM   3995 N  N    . GLN A 1 263 ? 141.087 211.796 151.965 1.00 88.29  ? 274 GLN A N    1 
ATOM   3996 C  CA   . GLN A 1 263 ? 140.206 212.612 151.136 1.00 85.68  ? 274 GLN A CA   1 
ATOM   3997 C  C    . GLN A 1 263 ? 138.998 211.805 150.680 1.00 82.31  ? 274 GLN A C    1 
ATOM   3998 O  O    . GLN A 1 263 ? 137.865 212.307 150.682 1.00 76.95  ? 274 GLN A O    1 
ATOM   3999 C  CB   . GLN A 1 263 ? 140.977 213.156 149.933 1.00 86.50  ? 274 GLN A CB   1 
ATOM   4000 H  H    . GLN A 1 263 ? 141.885 211.706 151.659 1.00 88.16  ? 274 GLN A H    1 
ATOM   4001 H  HA   . GLN A 1 263 ? 139.900 213.371 151.652 1.00 87.15  ? 274 GLN A HA   1 
ATOM   4002 N  N    . LEU A 1 264 ? 139.223 210.548 150.291 1.00 87.13  ? 275 LEU A N    1 
ATOM   4003 C  CA   . LEU A 1 264 ? 138.118 209.679 149.905 1.00 88.00  ? 275 LEU A CA   1 
ATOM   4004 C  C    . LEU A 1 264 ? 137.128 209.522 151.052 1.00 89.18  ? 275 LEU A C    1 
ATOM   4005 O  O    . LEU A 1 264 ? 135.913 209.624 150.854 1.00 90.40  ? 275 LEU A O    1 
ATOM   4006 C  CB   . LEU A 1 264 ? 138.664 208.319 149.462 1.00 88.59  ? 275 LEU A CB   1 
ATOM   4007 C  CG   . LEU A 1 264 ? 137.705 207.295 148.845 1.00 91.13  ? 275 LEU A CG   1 
ATOM   4008 C  CD1  . LEU A 1 264 ? 138.460 206.365 147.909 1.00 93.76  ? 275 LEU A CD1  1 
ATOM   4009 C  CD2  . LEU A 1 264 ? 137.009 206.462 149.912 1.00 91.35  ? 275 LEU A CD2  1 
ATOM   4010 H  H    . LEU A 1 264 ? 139.999 210.180 150.245 1.00 90.80  ? 275 LEU A H    1 
ATOM   4011 H  HA   . LEU A 1 264 ? 137.652 210.064 149.147 1.00 90.16  ? 275 LEU A HA   1 
ATOM   4012 H  HB2  . LEU A 1 264 ? 139.366 208.475 148.811 1.00 90.36  ? 275 LEU A HB2  1 
ATOM   4013 H  HB3  . LEU A 1 264 ? 139.050 207.897 150.246 1.00 90.80  ? 275 LEU A HB3  1 
ATOM   4014 H  HG   . LEU A 1 264 ? 137.028 207.761 148.330 1.00 90.48  ? 275 LEU A HG   1 
ATOM   4015 H  HD11 . LEU A 1 264 ? 137.843 205.698 147.569 1.00 91.09  ? 275 LEU A HD11 1 
ATOM   4016 H  HD12 . LEU A 1 264 ? 138.825 206.882 147.175 1.00 90.93  ? 275 LEU A HD12 1 
ATOM   4017 H  HD13 . LEU A 1 264 ? 139.176 205.933 148.401 1.00 91.51  ? 275 LEU A HD13 1 
ATOM   4018 H  HD21 . LEU A 1 264 ? 136.295 205.958 149.490 1.00 90.56  ? 275 LEU A HD21 1 
ATOM   4019 H  HD22 . LEU A 1 264 ? 137.653 205.853 150.306 1.00 90.66  ? 275 LEU A HD22 1 
ATOM   4020 H  HD23 . LEU A 1 264 ? 136.640 207.040 150.594 1.00 90.98  ? 275 LEU A HD23 1 
ATOM   4021 N  N    . ALA A 1 265 ? 137.634 209.285 152.263 1.00 102.95 ? 276 ALA A N    1 
ATOM   4022 C  CA   . ALA A 1 265 ? 136.754 209.079 153.407 1.00 106.14 ? 276 ALA A CA   1 
ATOM   4023 C  C    . ALA A 1 265 ? 135.939 210.330 153.703 1.00 108.79 ? 276 ALA A C    1 
ATOM   4024 O  O    . ALA A 1 265 ? 134.732 210.246 153.952 1.00 107.18 ? 276 ALA A O    1 
ATOM   4025 C  CB   . ALA A 1 265 ? 137.575 208.669 154.630 1.00 106.62 ? 276 ALA A CB   1 
ATOM   4026 H  H    . ALA A 1 265 ? 138.471 209.251 152.448 1.00 104.14 ? 276 ALA A H    1 
ATOM   4027 H  HA   . ALA A 1 265 ? 136.133 208.359 153.211 1.00 104.32 ? 276 ALA A HA   1 
ATOM   4028 H  HB1  . ALA A 1 265 ? 136.976 208.540 155.382 1.00 104.74 ? 276 ALA A HB1  1 
ATOM   4029 H  HB2  . ALA A 1 265 ? 138.044 207.843 154.431 1.00 105.29 ? 276 ALA A HB2  1 
ATOM   4030 H  HB3  . ALA A 1 265 ? 138.213 209.372 154.828 1.00 105.52 ? 276 ALA A HB3  1 
ATOM   4031 N  N    . ILE A 1 266 ? 136.573 211.503 153.663 1.00 122.09 ? 277 ILE A N    1 
ATOM   4032 C  CA   . ILE A 1 266 ? 135.848 212.728 153.993 1.00 120.12 ? 277 ILE A CA   1 
ATOM   4033 C  C    . ILE A 1 266 ? 134.808 213.040 152.923 1.00 116.43 ? 277 ILE A C    1 
ATOM   4034 O  O    . ILE A 1 266 ? 133.707 213.517 153.227 1.00 115.46 ? 277 ILE A O    1 
ATOM   4035 C  CB   . ILE A 1 266 ? 136.827 213.902 154.204 1.00 118.45 ? 277 ILE A CB   1 
ATOM   4036 C  CG1  . ILE A 1 266 ? 136.081 215.167 154.651 1.00 117.22 ? 277 ILE A CG1  1 
ATOM   4037 C  CG2  . ILE A 1 266 ? 137.610 214.187 152.944 1.00 114.39 ? 277 ILE A CG2  1 
ATOM   4038 C  CD1  . ILE A 1 266 ? 135.238 215.002 155.903 1.00 116.67 ? 277 ILE A CD1  1 
ATOM   4039 H  H    . ILE A 1 266 ? 137.396 211.614 153.440 1.00 116.17 ? 277 ILE A H    1 
ATOM   4040 H  HA   . ILE A 1 266 ? 135.374 212.580 154.826 1.00 116.72 ? 277 ILE A HA   1 
ATOM   4041 H  HB   . ILE A 1 266 ? 137.456 213.656 154.901 1.00 116.52 ? 277 ILE A HB   1 
ATOM   4042 H  HG12 . ILE A 1 266 ? 136.733 215.863 154.832 1.00 116.39 ? 277 ILE A HG12 1 
ATOM   4043 H  HG13 . ILE A 1 266 ? 135.492 215.455 153.935 1.00 116.75 ? 277 ILE A HG13 1 
ATOM   4044 H  HG21 . ILE A 1 266 ? 138.230 214.913 153.115 1.00 115.91 ? 277 ILE A HG21 1 
ATOM   4045 H  HG22 . ILE A 1 266 ? 138.095 213.388 152.708 1.00 115.03 ? 277 ILE A HG22 1 
ATOM   4046 H  HG23 . ILE A 1 266 ? 137.000 214.434 152.232 1.00 115.37 ? 277 ILE A HG23 1 
ATOM   4047 H  HD11 . ILE A 1 266 ? 134.972 215.881 156.220 1.00 116.46 ? 277 ILE A HD11 1 
ATOM   4048 H  HD12 . ILE A 1 266 ? 134.449 214.481 155.688 1.00 116.50 ? 277 ILE A HD12 1 
ATOM   4049 H  HD13 . ILE A 1 266 ? 135.762 214.551 156.582 1.00 116.51 ? 277 ILE A HD13 1 
ATOM   4050 N  N    . GLU A 1 267 ? 135.121 212.766 151.655 1.00 105.88 ? 278 GLU A N    1 
ATOM   4051 C  CA   . GLU A 1 267 ? 134.161 213.078 150.601 1.00 106.79 ? 278 GLU A CA   1 
ATOM   4052 C  C    . GLU A 1 267 ? 133.025 212.058 150.532 1.00 102.63 ? 278 GLU A C    1 
ATOM   4053 O  O    . GLU A 1 267 ? 131.911 212.414 150.131 1.00 102.52 ? 278 GLU A O    1 
ATOM   4054 C  CB   . GLU A 1 267 ? 134.894 213.204 149.263 1.00 105.26 ? 278 GLU A CB   1 
ATOM   4055 C  CG   . GLU A 1 267 ? 135.522 211.935 148.756 1.00 103.29 ? 278 GLU A CG   1 
ATOM   4056 C  CD   . GLU A 1 267 ? 136.290 212.160 147.471 1.00 105.63 ? 278 GLU A CD   1 
ATOM   4057 O  OE1  . GLU A 1 267 ? 136.341 213.317 146.999 1.00 104.19 ? 278 GLU A OE1  1 
ATOM   4058 O  OE2  . GLU A 1 267 ? 136.867 211.191 146.944 1.00 108.14 ? 278 GLU A OE2  1 
ATOM   4059 H  H    . GLU A 1 267 ? 135.862 212.414 151.387 1.00 104.37 ? 278 GLU A H    1 
ATOM   4060 H  HA   . GLU A 1 267 ? 133.763 213.941 150.795 1.00 105.37 ? 278 GLU A HA   1 
ATOM   4061 H  HB2  . GLU A 1 267 ? 134.275 213.521 148.589 1.00 104.63 ? 278 GLU A HB2  1 
ATOM   4062 H  HB3  . GLU A 1 267 ? 135.610 213.851 149.373 1.00 104.79 ? 278 GLU A HB3  1 
ATOM   4063 H  HG2  . GLU A 1 267 ? 136.125 211.580 149.424 1.00 103.78 ? 278 GLU A HG2  1 
ATOM   4064 H  HG3  . GLU A 1 267 ? 134.821 211.292 148.568 1.00 103.89 ? 278 GLU A HG3  1 
ATOM   4065 N  N    . LEU A 1 268 ? 133.255 210.806 150.942 1.00 90.59  ? 279 LEU A N    1 
ATOM   4066 C  CA   . LEU A 1 268 ? 132.123 209.911 151.170 1.00 91.24  ? 279 LEU A CA   1 
ATOM   4067 C  C    . LEU A 1 268 ? 131.322 210.296 152.404 1.00 95.31  ? 279 LEU A C    1 
ATOM   4068 O  O    . LEU A 1 268 ? 130.109 210.063 152.444 1.00 99.47  ? 279 LEU A O    1 
ATOM   4069 C  CB   . LEU A 1 268 ? 132.573 208.452 151.286 1.00 93.37  ? 279 LEU A CB   1 
ATOM   4070 C  CG   . LEU A 1 268 ? 132.962 207.687 150.015 1.00 95.52  ? 279 LEU A CG   1 
ATOM   4071 C  CD1  . LEU A 1 268 ? 134.111 208.286 149.236 1.00 95.58  ? 279 LEU A CD1  1 
ATOM   4072 C  CD2  . LEU A 1 268 ? 133.285 206.239 150.384 1.00 94.30  ? 279 LEU A CD2  1 
ATOM   4073 H  H    . LEU A 1 268 ? 134.028 210.458 151.084 1.00 94.74  ? 279 LEU A H    1 
ATOM   4074 H  HA   . LEU A 1 268 ? 131.531 209.979 150.405 1.00 94.34  ? 279 LEU A HA   1 
ATOM   4075 H  HB2  . LEU A 1 268 ? 133.345 208.435 151.873 1.00 94.51  ? 279 LEU A HB2  1 
ATOM   4076 H  HB3  . LEU A 1 268 ? 131.857 207.949 151.710 1.00 94.77  ? 279 LEU A HB3  1 
ATOM   4077 H  HG   . LEU A 1 268 ? 132.197 207.665 149.417 1.00 94.52  ? 279 LEU A HG   1 
ATOM   4078 H  HD11 . LEU A 1 268 ? 133.973 208.098 148.296 1.00 94.15  ? 279 LEU A HD11 1 
ATOM   4079 H  HD12 . LEU A 1 268 ? 134.138 209.241 149.374 1.00 94.79  ? 279 LEU A HD12 1 
ATOM   4080 H  HD13 . LEU A 1 268 ? 134.932 207.884 149.538 1.00 94.91  ? 279 LEU A HD13 1 
ATOM   4081 H  HD21 . LEU A 1 268 ? 133.832 205.855 149.682 1.00 94.26  ? 279 LEU A HD21 1 
ATOM   4082 H  HD22 . LEU A 1 268 ? 133.769 206.224 151.223 1.00 94.47  ? 279 LEU A HD22 1 
ATOM   4083 H  HD23 . LEU A 1 268 ? 132.459 205.740 150.472 1.00 93.98  ? 279 LEU A HD23 1 
ATOM   4084 N  N    . SER A 1 269 ? 131.969 210.866 153.420 1.00 107.36 ? 280 SER A N    1 
ATOM   4085 C  CA   . SER A 1 269 ? 131.216 211.388 154.553 1.00 110.16 ? 280 SER A CA   1 
ATOM   4086 C  C    . SER A 1 269 ? 130.284 212.508 154.107 1.00 112.51 ? 280 SER A C    1 
ATOM   4087 O  O    . SER A 1 269 ? 129.111 212.548 154.499 1.00 112.66 ? 280 SER A O    1 
ATOM   4088 C  CB   . SER A 1 269 ? 132.172 211.882 155.637 1.00 109.95 ? 280 SER A CB   1 
ATOM   4089 O  OG   . SER A 1 269 ? 133.201 210.938 155.889 1.00 109.04 ? 280 SER A OG   1 
ATOM   4090 H  H    . SER A 1 269 ? 132.820 210.964 153.474 1.00 108.81 ? 280 SER A H    1 
ATOM   4091 H  HA   . SER A 1 269 ? 130.677 210.677 154.931 1.00 109.25 ? 280 SER A HA   1 
ATOM   4092 H  HB2  . SER A 1 269 ? 132.573 212.715 155.341 1.00 109.70 ? 280 SER A HB2  1 
ATOM   4093 H  HB3  . SER A 1 269 ? 131.674 212.030 156.457 1.00 109.42 ? 280 SER A HB3  1 
ATOM   4094 H  HG   . SER A 1 269 ? 133.689 210.850 155.212 1.00 109.54 ? 280 SER A HG   1 
ATOM   4095 N  N    . CYS A 1 270 ? 130.788 213.419 153.270 1.00 115.62 ? 281 CYS A N    1 
ATOM   4096 C  CA   . CYS A 1 270 ? 129.940 214.493 152.760 1.00 115.30 ? 281 CYS A CA   1 
ATOM   4097 C  C    . CYS A 1 270 ? 128.911 213.967 151.765 1.00 113.61 ? 281 CYS A C    1 
ATOM   4098 O  O    . CYS A 1 270 ? 127.848 214.575 151.598 1.00 109.94 ? 281 CYS A O    1 
ATOM   4099 C  CB   . CYS A 1 270 ? 130.790 215.586 152.110 1.00 112.80 ? 281 CYS A CB   1 
ATOM   4100 S  SG   . CYS A 1 270 ? 131.330 215.225 150.427 1.00 114.09 ? 281 CYS A SG   1 
ATOM   4101 H  H    . CYS A 1 270 ? 131.601 213.439 152.991 1.00 112.68 ? 281 CYS A H    1 
ATOM   4102 H  HA   . CYS A 1 270 ? 129.459 214.891 153.503 1.00 113.46 ? 281 CYS A HA   1 
ATOM   4103 H  HB2  . CYS A 1 270 ? 130.270 216.405 152.084 1.00 113.19 ? 281 CYS A HB2  1 
ATOM   4104 H  HB3  . CYS A 1 270 ? 131.585 215.721 152.651 1.00 112.75 ? 281 CYS A HB3  1 
ATOM   4105 H  HG   . CYS A 1 270 ? 130.363 215.102 149.728 1.00 113.26 ? 281 CYS A HG   1 
ATOM   4106 N  N    . ARG A 1 271 ? 129.203 212.845 151.099 1.00 109.75 ? 282 ARG A N    1 
ATOM   4107 C  CA   . ARG A 1 271 ? 128.228 212.252 150.188 1.00 109.00 ? 282 ARG A CA   1 
ATOM   4108 C  C    . ARG A 1 271 ? 126.917 211.936 150.894 1.00 102.91 ? 282 ARG A C    1 
ATOM   4109 O  O    . ARG A 1 271 ? 125.860 211.909 150.254 1.00 106.70 ? 282 ARG A O    1 
ATOM   4110 C  CB   . ARG A 1 271 ? 128.798 210.979 149.562 1.00 107.59 ? 282 ARG A CB   1 
ATOM   4111 C  CG   . ARG A 1 271 ? 129.639 211.194 148.313 1.00 108.39 ? 282 ARG A CG   1 
ATOM   4112 C  CD   . ARG A 1 271 ? 128.765 211.491 147.104 1.00 109.41 ? 282 ARG A CD   1 
ATOM   4113 N  NE   . ARG A 1 271 ? 129.553 211.747 145.904 1.00 111.21 ? 282 ARG A NE   1 
ATOM   4114 C  CZ   . ARG A 1 271 ? 130.306 212.821 145.713 1.00 111.04 ? 282 ARG A CZ   1 
ATOM   4115 N  NH1  . ARG A 1 271 ? 130.385 213.782 146.619 1.00 110.93 ? 282 ARG A NH1  1 
ATOM   4116 N  NH2  . ARG A 1 271 ? 130.997 212.935 144.583 1.00 109.10 ? 282 ARG A NH2  1 
ATOM   4117 H  H    . ARG A 1 271 ? 129.946 212.414 151.158 1.00 107.43 ? 282 ARG A H    1 
ATOM   4118 H  HA   . ARG A 1 271 ? 128.038 212.881 149.474 1.00 107.85 ? 282 ARG A HA   1 
ATOM   4119 H  HB2  . ARG A 1 271 ? 129.361 210.542 150.218 1.00 106.76 ? 282 ARG A HB2  1 
ATOM   4120 H  HB3  . ARG A 1 271 ? 128.063 210.392 149.327 1.00 106.94 ? 282 ARG A HB3  1 
ATOM   4121 H  HG2  . ARG A 1 271 ? 130.237 211.943 148.451 1.00 107.31 ? 282 ARG A HG2  1 
ATOM   4122 H  HG3  . ARG A 1 271 ? 130.146 210.388 148.127 1.00 106.65 ? 282 ARG A HG3  1 
ATOM   4123 H  HD2  . ARG A 1 271 ? 128.190 210.728 146.932 1.00 106.70 ? 282 ARG A HD2  1 
ATOM   4124 H  HD3  . ARG A 1 271 ? 128.229 212.278 147.286 1.00 107.24 ? 282 ARG A HD3  1 
ATOM   4125 H  HE   . ARG A 1 271 ? 129.547 211.148 145.288 1.00 106.90 ? 282 ARG A HE   1 
ATOM   4126 H  HH11 . ARG A 1 271 ? 130.879 214.470 146.472 1.00 107.54 ? 282 ARG A HH11 1 
ATOM   4127 H  HH12 . ARG A 1 271 ? 129.943 213.721 147.354 1.00 107.81 ? 282 ARG A HH12 1 
ATOM   4128 H  HH21 . ARG A 1 271 ? 131.488 213.628 144.447 1.00 107.25 ? 282 ARG A HH21 1 
ATOM   4129 H  HH22 . ARG A 1 271 ? 130.953 212.316 143.988 1.00 106.84 ? 282 ARG A HH22 1 
ATOM   4130 N  N    . GLY A 1 272 ? 126.962 211.691 152.200 1.00 72.30  ? 283 GLY A N    1 
ATOM   4131 C  CA   . GLY A 1 272 ? 125.767 211.360 152.947 1.00 77.57  ? 283 GLY A CA   1 
ATOM   4132 C  C    . GLY A 1 272 ? 125.940 210.118 153.795 1.00 82.36  ? 283 GLY A C    1 
ATOM   4133 O  O    . GLY A 1 272 ? 125.170 209.887 154.733 1.00 86.40  ? 283 GLY A O    1 
ATOM   4134 H  H    . GLY A 1 272 ? 127.679 211.712 152.673 1.00 83.48  ? 283 GLY A H    1 
ATOM   4135 H  HA2  . GLY A 1 272 ? 125.535 212.100 153.529 1.00 82.54  ? 283 GLY A HA2  1 
ATOM   4136 H  HA3  . GLY A 1 272 ? 125.030 211.208 152.336 1.00 82.39  ? 283 GLY A HA3  1 
ATOM   4137 N  N    . VAL A 1 273 ? 126.945 209.310 153.475 1.00 85.12  ? 284 VAL A N    1 
ATOM   4138 C  CA   . VAL A 1 273 ? 127.249 208.094 154.219 1.00 85.43  ? 284 VAL A CA   1 
ATOM   4139 C  C    . VAL A 1 273 ? 128.499 208.351 155.049 1.00 84.08  ? 284 VAL A C    1 
ATOM   4140 O  O    . VAL A 1 273 ? 129.577 208.610 154.502 1.00 82.50  ? 284 VAL A O    1 
ATOM   4141 C  CB   . VAL A 1 273 ? 127.433 206.888 153.281 1.00 89.55  ? 284 VAL A CB   1 
ATOM   4142 C  CG1  . VAL A 1 273 ? 128.492 207.166 152.215 1.00 91.97  ? 284 VAL A CG1  1 
ATOM   4143 C  CG2  . VAL A 1 273 ? 127.789 205.640 154.079 1.00 86.65  ? 284 VAL A CG2  1 
ATOM   4144 H  H    . VAL A 1 273 ? 127.480 209.454 152.818 1.00 88.13  ? 284 VAL A H    1 
ATOM   4145 H  HA   . VAL A 1 273 ? 126.519 207.895 154.825 1.00 87.76  ? 284 VAL A HA   1 
ATOM   4146 H  HB   . VAL A 1 273 ? 126.594 206.717 152.826 1.00 88.80  ? 284 VAL A HB   1 
ATOM   4147 H  HG11 . VAL A 1 273 ? 128.508 206.422 151.594 1.00 88.77  ? 284 VAL A HG11 1 
ATOM   4148 H  HG12 . VAL A 1 273 ? 128.267 207.981 151.741 1.00 89.13  ? 284 VAL A HG12 1 
ATOM   4149 H  HG13 . VAL A 1 273 ? 129.360 207.255 152.638 1.00 88.88  ? 284 VAL A HG13 1 
ATOM   4150 H  HG21 . VAL A 1 273 ? 127.807 204.879 153.477 1.00 87.84  ? 284 VAL A HG21 1 
ATOM   4151 H  HG22 . VAL A 1 273 ? 128.662 205.758 154.485 1.00 87.83  ? 284 VAL A HG22 1 
ATOM   4152 H  HG23 . VAL A 1 273 ? 127.119 205.502 154.766 1.00 87.65  ? 284 VAL A HG23 1 
ATOM   4153 N  N    . ASN A 1 274 ? 128.355 208.288 156.369 1.00 92.90  ? 285 ASN A N    1 
ATOM   4154 C  CA   . ASN A 1 274 ? 129.483 208.536 157.254 1.00 94.17  ? 285 ASN A CA   1 
ATOM   4155 C  C    . ASN A 1 274 ? 130.535 207.448 157.089 1.00 94.57  ? 285 ASN A C    1 
ATOM   4156 O  O    . ASN A 1 274 ? 130.218 206.258 157.012 1.00 91.38  ? 285 ASN A O    1 
ATOM   4157 C  CB   . ASN A 1 274 ? 129.014 208.602 158.707 1.00 93.52  ? 285 ASN A CB   1 
ATOM   4158 C  CG   . ASN A 1 274 ? 130.107 209.059 159.652 1.00 92.43  ? 285 ASN A CG   1 
ATOM   4159 O  OD1  . ASN A 1 274 ? 131.239 209.308 159.238 1.00 92.25  ? 285 ASN A OD1  1 
ATOM   4160 N  ND2  . ASN A 1 274 ? 129.772 209.172 160.932 1.00 92.10  ? 285 ASN A ND2  1 
ATOM   4161 H  H    . ASN A 1 274 ? 127.618 208.105 156.774 1.00 93.07  ? 285 ASN A H    1 
ATOM   4162 H  HA   . ASN A 1 274 ? 129.887 209.388 157.025 1.00 93.74  ? 285 ASN A HA   1 
ATOM   4163 H  HB2  . ASN A 1 274 ? 128.279 209.231 158.773 1.00 93.45  ? 285 ASN A HB2  1 
ATOM   4164 H  HB3  . ASN A 1 274 ? 128.723 207.721 158.988 1.00 93.65  ? 285 ASN A HB3  1 
ATOM   4165 H  HD21 . ASN A 1 274 ? 128.970 208.989 161.185 1.00 93.55  ? 285 ASN A HD21 1 
ATOM   4166 H  HD22 . ASN A 1 274 ? 130.356 209.428 161.509 1.00 93.09  ? 285 ASN A HD22 1 
ATOM   4167 N  N    . ALA A 1 275 ? 131.797 207.866 157.036 1.00 99.94  ? 286 ALA A N    1 
ATOM   4168 C  CA   . ALA A 1 275 ? 132.901 206.938 156.856 1.00 96.87  ? 286 ALA A CA   1 
ATOM   4169 C  C    . ALA A 1 275 ? 134.158 207.549 157.455 1.00 99.66  ? 286 ALA A C    1 
ATOM   4170 O  O    . ALA A 1 275 ? 134.244 208.762 157.667 1.00 99.28  ? 286 ALA A O    1 
ATOM   4171 C  CB   . ALA A 1 275 ? 133.118 206.601 155.378 1.00 95.04  ? 286 ALA A CB   1 
ATOM   4172 H  H    . ALA A 1 275 ? 132.038 208.688 157.102 1.00 98.14  ? 286 ALA A H    1 
ATOM   4173 H  HA   . ALA A 1 275 ? 132.708 206.115 157.328 1.00 97.11  ? 286 ALA A HA   1 
ATOM   4174 H  HB1  . ALA A 1 275 ? 133.843 205.962 155.306 1.00 97.57  ? 286 ALA A HB1  1 
ATOM   4175 H  HB2  . ALA A 1 275 ? 132.302 206.219 155.019 1.00 96.96  ? 286 ALA A HB2  1 
ATOM   4176 H  HB3  . ALA A 1 275 ? 133.343 207.413 154.897 1.00 97.72  ? 286 ALA A HB3  1 
ATOM   4177 N  N    . LYS A 1 276 ? 135.135 206.689 157.728 1.00 95.92  ? 287 LYS A N    1 
ATOM   4178 C  CA   . LYS A 1 276 ? 136.401 207.102 158.312 1.00 94.83  ? 287 LYS A CA   1 
ATOM   4179 C  C    . LYS A 1 276 ? 137.544 206.431 157.567 1.00 89.99  ? 287 LYS A C    1 
ATOM   4180 O  O    . LYS A 1 276 ? 137.382 205.354 156.986 1.00 89.35  ? 287 LYS A O    1 
ATOM   4181 C  CB   . LYS A 1 276 ? 136.473 206.751 159.804 1.00 94.88  ? 287 LYS A CB   1 
ATOM   4182 H  H    . LYS A 1 276 ? 135.084 205.844 157.580 1.00 93.81  ? 287 LYS A H    1 
ATOM   4183 H  HA   . LYS A 1 276 ? 136.501 208.062 158.220 1.00 93.84  ? 287 LYS A HA   1 
ATOM   4184 N  N    . ALA A 1 277 ? 138.705 207.075 157.598 1.00 83.26  ? 288 ALA A N    1 
ATOM   4185 C  CA   . ALA A 1 277 ? 139.890 206.593 156.906 1.00 83.33  ? 288 ALA A CA   1 
ATOM   4186 C  C    . ALA A 1 277 ? 140.766 205.790 157.859 1.00 90.83  ? 288 ALA A C    1 
ATOM   4187 O  O    . ALA A 1 277 ? 140.951 206.169 159.019 1.00 95.95  ? 288 ALA A O    1 
ATOM   4188 C  CB   . ALA A 1 277 ? 140.688 207.760 156.325 1.00 87.82  ? 288 ALA A CB   1 
ATOM   4189 H  H    . ALA A 1 277 ? 138.832 207.812 158.023 1.00 90.29  ? 288 ALA A H    1 
ATOM   4190 H  HA   . ALA A 1 277 ? 139.624 206.016 156.175 1.00 89.68  ? 288 ALA A HA   1 
ATOM   4191 H  HB1  . ALA A 1 277 ? 141.441 207.411 155.825 1.00 91.43  ? 288 ALA A HB1  1 
ATOM   4192 H  HB2  . ALA A 1 277 ? 140.108 208.270 155.739 1.00 91.36  ? 288 ALA A HB2  1 
ATOM   4193 H  HB3  . ALA A 1 277 ? 141.001 208.322 157.051 1.00 91.05  ? 288 ALA A HB3  1 
ATOM   4194 N  N    . TYR A 1 278 ? 141.304 204.678 157.360 1.00 99.38  ? 289 TYR A N    1 
ATOM   4195 C  CA   . TYR A 1 278 ? 142.216 203.826 158.119 1.00 99.28  ? 289 TYR A CA   1 
ATOM   4196 C  C    . TYR A 1 278 ? 143.461 203.606 157.271 1.00 99.37  ? 289 TYR A C    1 
ATOM   4197 O  O    . TYR A 1 278 ? 143.429 202.838 156.304 1.00 103.52 ? 289 TYR A O    1 
ATOM   4198 C  CB   . TYR A 1 278 ? 141.558 202.493 158.481 1.00 99.39  ? 289 TYR A CB   1 
ATOM   4199 C  CG   . TYR A 1 278 ? 142.378 201.627 159.417 1.00 100.23 ? 289 TYR A CG   1 
ATOM   4200 C  CD1  . TYR A 1 278 ? 143.563 201.038 158.997 1.00 99.65  ? 289 TYR A CD1  1 
ATOM   4201 C  CD2  . TYR A 1 278 ? 141.960 201.394 160.720 1.00 101.00 ? 289 TYR A CD2  1 
ATOM   4202 C  CE1  . TYR A 1 278 ? 144.310 200.248 159.848 1.00 102.57 ? 289 TYR A CE1  1 
ATOM   4203 C  CE2  . TYR A 1 278 ? 142.700 200.604 161.578 1.00 102.24 ? 289 TYR A CE2  1 
ATOM   4204 C  CZ   . TYR A 1 278 ? 143.873 200.033 161.137 1.00 104.87 ? 289 TYR A CZ   1 
ATOM   4205 O  OH   . TYR A 1 278 ? 144.613 199.246 161.989 1.00 103.89 ? 289 TYR A OH   1 
ATOM   4206 H  H    . TYR A 1 278 ? 141.150 204.389 156.565 1.00 100.25 ? 289 TYR A H    1 
ATOM   4207 H  HA   . TYR A 1 278 ? 142.477 204.274 158.938 1.00 100.07 ? 289 TYR A HA   1 
ATOM   4208 H  HB2  . TYR A 1 278 ? 140.709 202.673 158.914 1.00 100.39 ? 289 TYR A HB2  1 
ATOM   4209 H  HB3  . TYR A 1 278 ? 141.411 201.988 157.667 1.00 100.77 ? 289 TYR A HB3  1 
ATOM   4210 H  HD1  . TYR A 1 278 ? 143.861 201.181 158.127 1.00 100.25 ? 289 TYR A HD1  1 
ATOM   4211 H  HD2  . TYR A 1 278 ? 141.168 201.777 161.020 1.00 100.51 ? 289 TYR A HD2  1 
ATOM   4212 H  HE1  . TYR A 1 278 ? 145.103 199.861 159.553 1.00 100.83 ? 289 TYR A HE1  1 
ATOM   4213 H  HE2  . TYR A 1 278 ? 142.408 200.457 162.448 1.00 100.70 ? 289 TYR A HE2  1 
ATOM   4214 H  HH   . TYR A 1 278 ? 144.232 199.194 162.735 1.00 101.02 ? 289 TYR A HH   1 
ATOM   4215 N  N    . HIS A 1 279 ? 144.552 204.273 157.631 1.00 102.91 ? 290 HIS A N    1 
ATOM   4216 C  CA   . HIS A 1 279 ? 145.791 204.169 156.874 1.00 104.79 ? 290 HIS A CA   1 
ATOM   4217 C  C    . HIS A 1 279 ? 146.947 204.598 157.765 1.00 106.02 ? 290 HIS A C    1 
ATOM   4218 O  O    . HIS A 1 279 ? 146.753 205.197 158.825 1.00 108.31 ? 290 HIS A O    1 
ATOM   4219 C  CB   . HIS A 1 279 ? 145.733 205.015 155.600 1.00 109.34 ? 290 HIS A CB   1 
ATOM   4220 C  CG   . HIS A 1 279 ? 145.449 206.463 155.850 1.00 109.01 ? 290 HIS A CG   1 
ATOM   4221 N  ND1  . HIS A 1 279 ? 146.445 207.406 155.984 1.00 105.15 ? 290 HIS A ND1  1 
ATOM   4222 C  CD2  . HIS A 1 279 ? 144.279 207.129 155.992 1.00 110.05 ? 290 HIS A CD2  1 
ATOM   4223 C  CE1  . HIS A 1 279 ? 145.901 208.591 156.195 1.00 107.33 ? 290 HIS A CE1  1 
ATOM   4224 N  NE2  . HIS A 1 279 ? 144.588 208.451 156.206 1.00 109.60 ? 290 HIS A NE2  1 
ATOM   4225 H  H    . HIS A 1 279 ? 144.600 204.794 158.314 1.00 106.37 ? 290 HIS A H    1 
ATOM   4226 H  HA   . HIS A 1 279 ? 145.932 203.244 156.618 1.00 106.83 ? 290 HIS A HA   1 
ATOM   4227 H  HB2  . HIS A 1 279 ? 146.587 204.952 155.147 1.00 107.61 ? 290 HIS A HB2  1 
ATOM   4228 H  HB3  . HIS A 1 279 ? 145.030 204.671 155.028 1.00 107.71 ? 290 HIS A HB3  1 
ATOM   4229 H  HD2  . HIS A 1 279 ? 143.427 206.761 155.952 1.00 107.36 ? 290 HIS A HD2  1 
ATOM   4230 H  HE1  . HIS A 1 279 ? 146.364 209.389 156.318 1.00 107.26 ? 290 HIS A HE1  1 
ATOM   4231 H  HE2  . HIS A 1 279 ? 144.018 209.083 156.326 1.00 107.46 ? 290 HIS A HE2  1 
ATOM   4232 N  N    . ALA A 1 280 ? 148.162 204.279 157.314 1.00 120.61 ? 291 ALA A N    1 
ATOM   4233 C  CA   . ALA A 1 280 ? 149.351 204.628 158.083 1.00 122.87 ? 291 ALA A CA   1 
ATOM   4234 C  C    . ALA A 1 280 ? 149.473 206.133 158.275 1.00 124.00 ? 291 ALA A C    1 
ATOM   4235 O  O    . ALA A 1 280 ? 149.993 206.588 159.300 1.00 122.48 ? 291 ALA A O    1 
ATOM   4236 C  CB   . ALA A 1 280 ? 150.600 204.079 157.394 1.00 121.17 ? 291 ALA A CB   1 
ATOM   4237 H  H    . ALA A 1 280 ? 148.321 203.866 156.576 1.00 120.90 ? 291 ALA A H    1 
ATOM   4238 H  HA   . ALA A 1 280 ? 149.290 204.219 158.961 1.00 121.36 ? 291 ALA A HA   1 
ATOM   4239 H  HB1  . ALA A 1 280 ? 151.381 204.320 157.916 1.00 121.24 ? 291 ALA A HB1  1 
ATOM   4240 H  HB2  . ALA A 1 280 ? 150.528 203.114 157.331 1.00 121.21 ? 291 ALA A HB2  1 
ATOM   4241 H  HB3  . ALA A 1 280 ? 150.664 204.464 156.506 1.00 121.26 ? 291 ALA A HB3  1 
ATOM   4242 N  N    . GLY A 1 281 ? 149.006 206.919 157.304 1.00 120.46 ? 292 GLY A N    1 
ATOM   4243 C  CA   . GLY A 1 281 ? 149.082 208.365 157.439 1.00 118.02 ? 292 GLY A CA   1 
ATOM   4244 C  C    . GLY A 1 281 ? 148.324 208.877 158.649 1.00 117.50 ? 292 GLY A C    1 
ATOM   4245 O  O    . GLY A 1 281 ? 148.764 209.817 159.317 1.00 119.61 ? 292 GLY A O    1 
ATOM   4246 H  H    . GLY A 1 281 ? 148.650 206.643 156.572 1.00 118.16 ? 292 GLY A H    1 
ATOM   4247 H  HA2  . GLY A 1 281 ? 150.011 208.631 157.525 1.00 118.77 ? 292 GLY A HA2  1 
ATOM   4248 H  HA3  . GLY A 1 281 ? 148.714 208.784 156.646 1.00 118.04 ? 292 GLY A HA3  1 
ATOM   4249 N  N    . LEU A 1 282 ? 147.179 208.272 158.946 1.00 113.81 ? 293 LEU A N    1 
ATOM   4250 C  CA   . LEU A 1 282 ? 146.396 208.680 160.102 1.00 116.88 ? 293 LEU A CA   1 
ATOM   4251 C  C    . LEU A 1 282 ? 147.128 208.322 161.391 1.00 118.40 ? 293 LEU A C    1 
ATOM   4252 O  O    . LEU A 1 282 ? 147.813 207.300 161.482 1.00 117.26 ? 293 LEU A O    1 
ATOM   4253 C  CB   . LEU A 1 282 ? 145.020 208.015 160.074 1.00 117.42 ? 293 LEU A CB   1 
ATOM   4254 C  CG   . LEU A 1 282 ? 144.062 208.390 161.207 1.00 116.73 ? 293 LEU A CG   1 
ATOM   4255 C  CD1  . LEU A 1 282 ? 143.756 209.880 161.177 1.00 115.51 ? 293 LEU A CD1  1 
ATOM   4256 C  CD2  . LEU A 1 282 ? 142.781 207.577 161.115 1.00 114.90 ? 293 LEU A CD2  1 
ATOM   4257 H  H    . LEU A 1 282 ? 146.836 207.624 158.496 1.00 115.05 ? 293 LEU A H    1 
ATOM   4258 H  HA   . LEU A 1 282 ? 146.271 209.642 160.079 1.00 115.83 ? 293 LEU A HA   1 
ATOM   4259 H  HB2  . LEU A 1 282 ? 144.585 208.249 159.239 1.00 115.60 ? 293 LEU A HB2  1 
ATOM   4260 H  HB3  . LEU A 1 282 ? 145.146 207.054 160.111 1.00 115.76 ? 293 LEU A HB3  1 
ATOM   4261 H  HG   . LEU A 1 282 ? 144.482 208.188 162.058 1.00 115.93 ? 293 LEU A HG   1 
ATOM   4262 H  HD11 . LEU A 1 282 ? 142.989 210.057 161.745 1.00 115.56 ? 293 LEU A HD11 1 
ATOM   4263 H  HD12 . LEU A 1 282 ? 144.528 210.369 161.502 1.00 115.63 ? 293 LEU A HD12 1 
ATOM   4264 H  HD13 . LEU A 1 282 ? 143.556 210.143 160.265 1.00 115.76 ? 293 LEU A HD13 1 
ATOM   4265 H  HD21 . LEU A 1 282 ? 142.216 207.792 161.874 1.00 115.31 ? 293 LEU A HD21 1 
ATOM   4266 H  HD22 . LEU A 1 282 ? 142.325 207.800 160.289 1.00 115.27 ? 293 LEU A HD22 1 
ATOM   4267 H  HD23 . LEU A 1 282 ? 143.005 206.633 161.126 1.00 115.36 ? 293 LEU A HD23 1 
ATOM   4268 N  N    . LYS A 1 283 ? 146.976 209.181 162.395 1.00 117.01 ? 294 LYS A N    1 
ATOM   4269 C  CA   . LYS A 1 283 ? 147.648 208.965 163.668 1.00 115.77 ? 294 LYS A CA   1 
ATOM   4270 C  C    . LYS A 1 283 ? 147.121 207.704 164.347 1.00 114.61 ? 294 LYS A C    1 
ATOM   4271 O  O    . LYS A 1 283 ? 145.977 207.290 164.141 1.00 115.82 ? 294 LYS A O    1 
ATOM   4272 C  CB   . LYS A 1 283 ? 147.466 210.181 164.579 1.00 113.39 ? 294 LYS A CB   1 
ATOM   4273 C  CG   . LYS A 1 283 ? 146.019 210.523 164.887 1.00 114.08 ? 294 LYS A CG   1 
ATOM   4274 C  CD   . LYS A 1 283 ? 145.911 211.738 165.796 1.00 114.04 ? 294 LYS A CD   1 
ATOM   4275 C  CE   . LYS A 1 283 ? 146.078 213.037 165.021 1.00 114.49 ? 294 LYS A CE   1 
ATOM   4276 N  NZ   . LYS A 1 283 ? 144.923 213.305 164.120 1.00 117.16 ? 294 LYS A NZ   1 
ATOM   4277 H  H    . LYS A 1 283 ? 146.493 209.891 162.363 1.00 114.95 ? 294 LYS A H    1 
ATOM   4278 H  HA   . LYS A 1 283 ? 148.598 208.848 163.510 1.00 115.12 ? 294 LYS A HA   1 
ATOM   4279 H  HB2  . LYS A 1 283 ? 147.913 210.007 165.422 1.00 114.57 ? 294 LYS A HB2  1 
ATOM   4280 H  HB3  . LYS A 1 283 ? 147.867 210.952 164.150 1.00 114.46 ? 294 LYS A HB3  1 
ATOM   4281 H  HG2  . LYS A 1 283 ? 145.550 210.718 164.060 1.00 114.73 ? 294 LYS A HG2  1 
ATOM   4282 H  HG3  . LYS A 1 283 ? 145.606 209.775 165.338 1.00 114.63 ? 294 LYS A HG3  1 
ATOM   4283 H  HD2  . LYS A 1 283 ? 145.037 211.746 166.216 1.00 114.67 ? 294 LYS A HD2  1 
ATOM   4284 H  HD3  . LYS A 1 283 ? 146.607 211.696 166.470 1.00 114.48 ? 294 LYS A HD3  1 
ATOM   4285 H  HE2  . LYS A 1 283 ? 146.149 213.773 165.648 1.00 114.75 ? 294 LYS A HE2  1 
ATOM   4286 H  HE3  . LYS A 1 283 ? 146.879 212.984 164.477 1.00 114.50 ? 294 LYS A HE3  1 
ATOM   4287 H  HZ1  . LYS A 1 283 ? 144.857 212.662 163.509 1.00 115.13 ? 294 LYS A HZ1  1 
ATOM   4288 H  HZ2  . LYS A 1 283 ? 144.169 213.333 164.593 1.00 115.24 ? 294 LYS A HZ2  1 
ATOM   4289 H  HZ3  . LYS A 1 283 ? 145.034 214.086 163.707 1.00 115.04 ? 294 LYS A HZ3  1 
ATOM   4290 N  N    . ALA A 1 284 ? 147.980 207.092 165.167 1.00 101.71 ? 295 ALA A N    1 
ATOM   4291 C  CA   . ALA A 1 284 ? 147.662 205.786 165.736 1.00 101.18 ? 295 ALA A CA   1 
ATOM   4292 C  C    . ALA A 1 284 ? 146.383 205.831 166.559 1.00 99.88  ? 295 ALA A C    1 
ATOM   4293 O  O    . ALA A 1 284 ? 145.543 204.928 166.462 1.00 100.57 ? 295 ALA A O    1 
ATOM   4294 C  CB   . ALA A 1 284 ? 148.828 205.291 166.591 1.00 100.13 ? 295 ALA A CB   1 
ATOM   4295 H  H    . ALA A 1 284 ? 148.742 207.410 165.406 1.00 102.00 ? 295 ALA A H    1 
ATOM   4296 H  HA   . ALA A 1 284 ? 147.531 205.150 165.016 1.00 102.02 ? 295 ALA A HA   1 
ATOM   4297 H  HB1  . ALA A 1 284 ? 148.603 204.423 166.960 1.00 101.37 ? 295 ALA A HB1  1 
ATOM   4298 H  HB2  . ALA A 1 284 ? 149.619 205.219 166.034 1.00 101.86 ? 295 ALA A HB2  1 
ATOM   4299 H  HB3  . ALA A 1 284 ? 148.985 205.925 167.308 1.00 101.25 ? 295 ALA A HB3  1 
ATOM   4300 N  N    . SER A 1 285 ? 146.215 206.869 167.379 1.00 108.39 ? 296 SER A N    1 
ATOM   4301 C  CA   . SER A 1 285 ? 144.996 206.982 168.172 1.00 113.62 ? 296 SER A CA   1 
ATOM   4302 C  C    . SER A 1 285 ? 143.769 207.067 167.273 1.00 116.54 ? 296 SER A C    1 
ATOM   4303 O  O    . SER A 1 285 ? 142.757 206.401 167.521 1.00 115.97 ? 296 SER A O    1 
ATOM   4304 C  CB   . SER A 1 285 ? 145.080 208.205 169.085 1.00 113.32 ? 296 SER A CB   1 
ATOM   4305 O  OG   . SER A 1 285 ? 145.188 209.398 168.329 1.00 111.60 ? 296 SER A OG   1 
ATOM   4306 H  H    . SER A 1 285 ? 146.781 207.507 167.492 1.00 112.00 ? 296 SER A H    1 
ATOM   4307 H  HA   . SER A 1 285 ? 144.906 206.194 168.730 1.00 113.00 ? 296 SER A HA   1 
ATOM   4308 H  HB2  . SER A 1 285 ? 144.279 208.247 169.630 1.00 113.01 ? 296 SER A HB2  1 
ATOM   4309 H  HB3  . SER A 1 285 ? 145.862 208.120 169.653 1.00 112.91 ? 296 SER A HB3  1 
ATOM   4310 H  HG   . SER A 1 285 ? 145.876 209.372 167.848 1.00 112.44 ? 296 SER A HG   1 
ATOM   4311 N  N    . GLU A 1 286 ? 143.849 207.869 166.210 1.00 122.98 ? 297 GLU A N    1 
ATOM   4312 C  CA   . GLU A 1 286 ? 142.736 207.968 165.272 1.00 122.26 ? 297 GLU A CA   1 
ATOM   4313 C  C    . GLU A 1 286 ? 142.528 206.656 164.527 1.00 121.70 ? 297 GLU A C    1 
ATOM   4314 O  O    . GLU A 1 286 ? 141.390 206.286 164.218 1.00 121.36 ? 297 GLU A O    1 
ATOM   4315 C  CB   . GLU A 1 286 ? 142.983 209.111 164.288 1.00 119.22 ? 297 GLU A CB   1 
ATOM   4316 H  H    . GLU A 1 286 ? 144.527 208.353 166.014 1.00 120.00 ? 297 GLU A H    1 
ATOM   4317 H  HA   . GLU A 1 286 ? 141.924 208.166 165.764 1.00 120.60 ? 297 GLU A HA   1 
ATOM   4318 N  N    . ARG A 1 287 ? 143.614 205.944 164.220 1.00 113.45 ? 298 ARG A N    1 
ATOM   4319 C  CA   . ARG A 1 287 ? 143.486 204.646 163.566 1.00 111.88 ? 298 ARG A CA   1 
ATOM   4320 C  C    . ARG A 1 287 ? 142.709 203.672 164.445 1.00 110.77 ? 298 ARG A C    1 
ATOM   4321 O  O    . ARG A 1 287 ? 141.795 202.983 163.977 1.00 108.08 ? 298 ARG A O    1 
ATOM   4322 C  CB   . ARG A 1 287 ? 144.872 204.092 163.234 1.00 109.21 ? 298 ARG A CB   1 
ATOM   4323 C  CG   . ARG A 1 287 ? 145.558 204.806 162.079 1.00 110.19 ? 298 ARG A CG   1 
ATOM   4324 C  CD   . ARG A 1 287 ? 147.052 204.520 162.047 1.00 108.04 ? 298 ARG A CD   1 
ATOM   4325 N  NE   . ARG A 1 287 ? 147.348 203.097 162.169 1.00 108.71 ? 298 ARG A NE   1 
ATOM   4326 C  CZ   . ARG A 1 287 ? 147.072 202.190 161.242 1.00 109.41 ? 298 ARG A CZ   1 
ATOM   4327 N  NH1  . ARG A 1 287 ? 146.500 202.522 160.096 1.00 107.77 ? 298 ARG A NH1  1 
ATOM   4328 N  NH2  . ARG A 1 287 ? 147.380 200.916 161.469 1.00 110.50 ? 298 ARG A NH2  1 
ATOM   4329 H  H    . ARG A 1 287 ? 144.424 206.188 164.377 1.00 110.59 ? 298 ARG A H    1 
ATOM   4330 H  HA   . ARG A 1 287 ? 143.003 204.757 162.733 1.00 110.40 ? 298 ARG A HA   1 
ATOM   4331 H  HB2  . ARG A 1 287 ? 145.439 204.179 164.016 1.00 109.49 ? 298 ARG A HB2  1 
ATOM   4332 H  HB3  . ARG A 1 287 ? 144.784 203.156 162.994 1.00 109.73 ? 298 ARG A HB3  1 
ATOM   4333 H  HG2  . ARG A 1 287 ? 145.171 204.506 161.243 1.00 110.01 ? 298 ARG A HG2  1 
ATOM   4334 H  HG3  . ARG A 1 287 ? 145.436 205.763 162.179 1.00 110.45 ? 298 ARG A HG3  1 
ATOM   4335 H  HD2  . ARG A 1 287 ? 147.415 204.830 161.203 1.00 110.15 ? 298 ARG A HD2  1 
ATOM   4336 H  HD3  . ARG A 1 287 ? 147.482 204.982 162.783 1.00 109.45 ? 298 ARG A HD3  1 
ATOM   4337 H  HE   . ARG A 1 287 ? 147.733 202.828 162.889 1.00 109.71 ? 298 ARG A HE   1 
ATOM   4338 H  HH11 . ARG A 1 287 ? 146.297 203.342 159.936 1.00 109.69 ? 298 ARG A HH11 1 
ATOM   4339 H  HH12 . ARG A 1 287 ? 146.332 201.917 159.509 1.00 109.05 ? 298 ARG A HH12 1 
ATOM   4340 H  HH21 . ARG A 1 287 ? 147.752 200.689 162.210 1.00 110.32 ? 298 ARG A HH21 1 
ATOM   4341 H  HH22 . ARG A 1 287 ? 147.207 200.319 160.874 1.00 109.50 ? 298 ARG A HH22 1 
ATOM   4342 N  N    . THR A 1 288 ? 143.050 203.615 165.734 1.00 108.41 ? 299 THR A N    1 
ATOM   4343 C  CA   . THR A 1 288 ? 142.312 202.753 166.652 1.00 109.43 ? 299 THR A CA   1 
ATOM   4344 C  C    . THR A 1 288 ? 140.868 203.215 166.798 1.00 104.55 ? 299 THR A C    1 
ATOM   4345 O  O    . THR A 1 288 ? 139.951 202.390 166.893 1.00 103.69 ? 299 THR A O    1 
ATOM   4346 C  CB   . THR A 1 288 ? 143.002 202.717 168.017 1.00 111.11 ? 299 THR A CB   1 
ATOM   4347 O  OG1  . THR A 1 288 ? 142.990 204.026 168.601 1.00 112.02 ? 299 THR A OG1  1 
ATOM   4348 C  CG2  . THR A 1 288 ? 144.438 202.221 167.887 1.00 110.41 ? 299 THR A CG2  1 
ATOM   4349 H  H    . THR A 1 288 ? 143.693 204.058 166.094 1.00 108.47 ? 299 THR A H    1 
ATOM   4350 H  HA   . THR A 1 288 ? 142.303 201.850 166.298 1.00 108.65 ? 299 THR A HA   1 
ATOM   4351 H  HB   . THR A 1 288 ? 142.523 202.105 168.599 1.00 108.66 ? 299 THR A HB   1 
ATOM   4352 H  HG1  . THR A 1 288 ? 143.400 204.565 168.105 1.00 109.24 ? 299 THR A HG1  1 
ATOM   4353 H  HG21 . THR A 1 288 ? 144.444 201.322 167.523 1.00 108.55 ? 299 THR A HG21 1 
ATOM   4354 H  HG22 . THR A 1 288 ? 144.942 202.801 167.298 1.00 108.55 ? 299 THR A HG22 1 
ATOM   4355 H  HG23 . THR A 1 288 ? 144.864 202.209 168.758 1.00 108.60 ? 299 THR A HG23 1 
ATOM   4356 N  N    . LEU A 1 289 ? 140.645 204.529 166.826 1.00 93.97  ? 300 LEU A N    1 
ATOM   4357 C  CA   . LEU A 1 289 ? 139.284 205.043 166.937 1.00 97.46  ? 300 LEU A CA   1 
ATOM   4358 C  C    . LEU A 1 289 ? 138.434 204.598 165.752 1.00 103.90 ? 300 LEU A C    1 
ATOM   4359 O  O    . LEU A 1 289 ? 137.302 204.131 165.923 1.00 106.13 ? 300 LEU A O    1 
ATOM   4360 C  CB   . LEU A 1 289 ? 139.314 206.569 167.042 1.00 97.63  ? 300 LEU A CB   1 
ATOM   4361 C  CG   . LEU A 1 289 ? 137.963 207.288 166.985 1.00 102.62 ? 300 LEU A CG   1 
ATOM   4362 C  CD1  . LEU A 1 289 ? 137.957 208.475 167.935 1.00 102.15 ? 300 LEU A CD1  1 
ATOM   4363 C  CD2  . LEU A 1 289 ? 137.639 207.744 165.568 1.00 103.94 ? 300 LEU A CD2  1 
ATOM   4364 H  H    . LEU A 1 289 ? 141.254 205.134 166.783 1.00 101.63 ? 300 LEU A H    1 
ATOM   4365 H  HA   . LEU A 1 289 ? 138.878 204.694 167.746 1.00 101.38 ? 300 LEU A HA   1 
ATOM   4366 H  HB2  . LEU A 1 289 ? 139.730 206.805 167.886 1.00 101.25 ? 300 LEU A HB2  1 
ATOM   4367 H  HB3  . LEU A 1 289 ? 139.854 206.911 166.313 1.00 101.54 ? 300 LEU A HB3  1 
ATOM   4368 H  HG   . LEU A 1 289 ? 137.267 206.675 167.269 1.00 101.80 ? 300 LEU A HG   1 
ATOM   4369 H  HD11 . LEU A 1 289 ? 137.104 208.930 167.865 1.00 101.63 ? 300 LEU A HD11 1 
ATOM   4370 H  HD12 . LEU A 1 289 ? 138.089 208.155 168.841 1.00 101.88 ? 300 LEU A HD12 1 
ATOM   4371 H  HD13 . LEU A 1 289 ? 138.675 209.079 167.689 1.00 101.68 ? 300 LEU A HD13 1 
ATOM   4372 H  HD21 . LEU A 1 289 ? 136.842 208.295 165.590 1.00 101.79 ? 300 LEU A HD21 1 
ATOM   4373 H  HD22 . LEU A 1 289 ? 138.386 208.258 165.223 1.00 102.22 ? 300 LEU A HD22 1 
ATOM   4374 H  HD23 . LEU A 1 289 ? 137.487 206.967 165.008 1.00 101.92 ? 300 LEU A HD23 1 
ATOM   4375 N  N    . VAL A 1 290 ? 138.969 204.731 164.536 1.00 106.04 ? 301 VAL A N    1 
ATOM   4376 C  CA   . VAL A 1 290 ? 138.209 204.330 163.356 1.00 104.90 ? 301 VAL A CA   1 
ATOM   4377 C  C    . VAL A 1 290 ? 138.035 202.817 163.316 1.00 103.02 ? 301 VAL A C    1 
ATOM   4378 O  O    . VAL A 1 290 ? 136.995 202.319 162.871 1.00 102.14 ? 301 VAL A O    1 
ATOM   4379 C  CB   . VAL A 1 290 ? 138.872 204.859 162.069 1.00 105.47 ? 301 VAL A CB   1 
ATOM   4380 C  CG1  . VAL A 1 290 ? 138.883 206.382 162.067 1.00 105.97 ? 301 VAL A CG1  1 
ATOM   4381 C  CG2  . VAL A 1 290 ? 140.278 204.312 161.910 1.00 103.08 ? 301 VAL A CG2  1 
ATOM   4382 H  H    . VAL A 1 290 ? 139.753 205.044 164.373 1.00 105.00 ? 301 VAL A H    1 
ATOM   4383 H  HA   . VAL A 1 290 ? 137.325 204.723 163.411 1.00 104.29 ? 301 VAL A HA   1 
ATOM   4384 H  HB   . VAL A 1 290 ? 138.351 204.566 161.305 1.00 104.34 ? 301 VAL A HB   1 
ATOM   4385 H  HG11 . VAL A 1 290 ? 139.266 206.694 161.232 1.00 104.21 ? 301 VAL A HG11 1 
ATOM   4386 H  HG12 . VAL A 1 290 ? 137.973 206.704 162.155 1.00 104.43 ? 301 VAL A HG12 1 
ATOM   4387 H  HG13 . VAL A 1 290 ? 139.417 206.695 162.814 1.00 105.10 ? 301 VAL A HG13 1 
ATOM   4388 H  HG21 . VAL A 1 290 ? 140.634 204.605 161.057 1.00 103.91 ? 301 VAL A HG21 1 
ATOM   4389 H  HG22 . VAL A 1 290 ? 140.827 204.653 162.629 1.00 104.73 ? 301 VAL A HG22 1 
ATOM   4390 H  HG23 . VAL A 1 290 ? 140.252 203.344 161.940 1.00 104.06 ? 301 VAL A HG23 1 
ATOM   4391 N  N    . GLN A 1 291 ? 139.035 202.058 163.770 1.00 98.33  ? 302 GLN A N    1 
ATOM   4392 C  CA   . GLN A 1 291 ? 138.883 200.608 163.833 1.00 99.81  ? 302 GLN A CA   1 
ATOM   4393 C  C    . GLN A 1 291 ? 137.735 200.233 164.762 1.00 104.49 ? 302 GLN A C    1 
ATOM   4394 O  O    . GLN A 1 291 ? 136.892 199.390 164.426 1.00 104.72 ? 302 GLN A O    1 
ATOM   4395 C  CB   . GLN A 1 291 ? 140.201 199.975 164.291 1.00 99.98  ? 302 GLN A CB   1 
ATOM   4396 C  CG   . GLN A 1 291 ? 140.410 198.508 163.896 1.00 105.88 ? 302 GLN A CG   1 
ATOM   4397 C  CD   . GLN A 1 291 ? 139.454 197.533 164.565 1.00 105.33 ? 302 GLN A CD   1 
ATOM   4398 O  OE1  . GLN A 1 291 ? 138.724 197.884 165.490 1.00 107.49 ? 302 GLN A OE1  1 
ATOM   4399 N  NE2  . GLN A 1 291 ? 139.458 196.293 164.092 1.00 104.01 ? 302 GLN A NE2  1 
ATOM   4400 H  H    . GLN A 1 291 ? 139.796 202.353 164.041 1.00 102.58 ? 302 GLN A H    1 
ATOM   4401 H  HA   . GLN A 1 291 ? 138.677 200.271 162.947 1.00 102.76 ? 302 GLN A HA   1 
ATOM   4402 H  HB2  . GLN A 1 291 ? 140.933 200.485 163.914 1.00 102.65 ? 302 GLN A HB2  1 
ATOM   4403 H  HB3  . GLN A 1 291 ? 140.241 200.021 165.259 1.00 102.53 ? 302 GLN A HB3  1 
ATOM   4404 H  HG2  . GLN A 1 291 ? 140.290 198.426 162.937 1.00 103.91 ? 302 GLN A HG2  1 
ATOM   4405 H  HG3  . GLN A 1 291 ? 141.313 198.248 164.136 1.00 103.51 ? 302 GLN A HG3  1 
ATOM   4406 H  HE21 . GLN A 1 291 ? 139.982 196.081 163.444 1.00 103.32 ? 302 GLN A HE21 1 
ATOM   4407 H  HE22 . GLN A 1 291 ? 138.937 195.701 164.435 1.00 103.29 ? 302 GLN A HE22 1 
ATOM   4408 N  N    . ASN A 1 292 ? 137.680 200.863 165.938 1.00 112.15 ? 303 ASN A N    1 
ATOM   4409 C  CA   . ASN A 1 292 ? 136.589 200.596 166.869 1.00 112.84 ? 303 ASN A CA   1 
ATOM   4410 C  C    . ASN A 1 292 ? 135.249 200.998 166.268 1.00 109.17 ? 303 ASN A C    1 
ATOM   4411 O  O    . ASN A 1 292 ? 134.252 200.283 166.420 1.00 109.22 ? 303 ASN A O    1 
ATOM   4412 C  CB   . ASN A 1 292 ? 136.830 201.337 168.184 1.00 112.26 ? 303 ASN A CB   1 
ATOM   4413 C  CG   . ASN A 1 292 ? 138.143 200.952 168.839 1.00 112.38 ? 303 ASN A CG   1 
ATOM   4414 O  OD1  . ASN A 1 292 ? 138.920 201.813 169.251 1.00 112.46 ? 303 ASN A OD1  1 
ATOM   4415 N  ND2  . ASN A 1 292 ? 138.395 199.652 168.942 1.00 112.51 ? 303 ASN A ND2  1 
ATOM   4416 H  H    . ASN A 1 292 ? 138.254 201.441 166.214 1.00 110.52 ? 303 ASN A H    1 
ATOM   4417 H  HA   . ASN A 1 292 ? 136.559 199.646 167.058 1.00 111.23 ? 303 ASN A HA   1 
ATOM   4418 H  HB2  . ASN A 1 292 ? 136.850 202.291 168.011 1.00 111.13 ? 303 ASN A HB2  1 
ATOM   4419 H  HB3  . ASN A 1 292 ? 136.113 201.126 168.802 1.00 111.13 ? 303 ASN A HB3  1 
ATOM   4420 H  HD21 . ASN A 1 292 ? 137.829 199.078 168.644 1.00 111.30 ? 303 ASN A HD21 1 
ATOM   4421 H  HD22 . ASN A 1 292 ? 139.127 199.384 169.307 1.00 111.23 ? 303 ASN A HD22 1 
ATOM   4422 N  N    . ASP A 1 293 ? 135.207 202.141 165.580 1.00 101.71 ? 304 ASP A N    1 
ATOM   4423 C  CA   . ASP A 1 293 ? 133.965 202.568 164.946 1.00 103.62 ? 304 ASP A CA   1 
ATOM   4424 C  C    . ASP A 1 293 ? 133.499 201.546 163.917 1.00 105.38 ? 304 ASP A C    1 
ATOM   4425 O  O    . ASP A 1 293 ? 132.307 201.227 163.842 1.00 109.61 ? 304 ASP A O    1 
ATOM   4426 C  CB   . ASP A 1 293 ? 134.154 203.937 164.295 1.00 107.39 ? 304 ASP A CB   1 
ATOM   4427 C  CG   . ASP A 1 293 ? 134.226 205.061 165.311 1.00 106.16 ? 304 ASP A CG   1 
ATOM   4428 O  OD1  . ASP A 1 293 ? 133.593 204.939 166.381 1.00 104.08 ? 304 ASP A OD1  1 
ATOM   4429 O  OD2  . ASP A 1 293 ? 134.916 206.066 165.039 1.00 106.46 ? 304 ASP A OD2  1 
ATOM   4430 H  H    . ASP A 1 293 ? 135.871 202.675 165.468 1.00 105.14 ? 304 ASP A H    1 
ATOM   4431 H  HA   . ASP A 1 293 ? 133.274 202.647 165.622 1.00 105.29 ? 304 ASP A HA   1 
ATOM   4432 H  HB2  . ASP A 1 293 ? 134.982 203.936 163.790 1.00 105.55 ? 304 ASP A HB2  1 
ATOM   4433 H  HB3  . ASP A 1 293 ? 133.405 204.114 163.705 1.00 105.81 ? 304 ASP A HB3  1 
ATOM   4434 N  N    . TRP A 1 294 ? 134.427 201.021 163.116 1.00 102.02 ? 305 TRP A N    1 
ATOM   4435 C  CA   . TRP A 1 294 ? 134.074 199.979 162.158 1.00 103.76 ? 305 TRP A CA   1 
ATOM   4436 C  C    . TRP A 1 294 ? 133.542 198.743 162.868 1.00 108.99 ? 305 TRP A C    1 
ATOM   4437 O  O    . TRP A 1 294 ? 132.533 198.160 162.454 1.00 110.65 ? 305 TRP A O    1 
ATOM   4438 C  CB   . TRP A 1 294 ? 135.286 199.618 161.301 1.00 104.90 ? 305 TRP A CB   1 
ATOM   4439 C  CG   . TRP A 1 294 ? 135.049 198.418 160.440 1.00 104.91 ? 305 TRP A CG   1 
ATOM   4440 C  CD1  . TRP A 1 294 ? 134.191 198.322 159.385 1.00 101.60 ? 305 TRP A CD1  1 
ATOM   4441 C  CD2  . TRP A 1 294 ? 135.672 197.135 160.570 1.00 107.41 ? 305 TRP A CD2  1 
ATOM   4442 N  NE1  . TRP A 1 294 ? 134.245 197.059 158.845 1.00 101.80 ? 305 TRP A NE1  1 
ATOM   4443 C  CE2  . TRP A 1 294 ? 135.146 196.311 159.556 1.00 103.89 ? 305 TRP A CE2  1 
ATOM   4444 C  CE3  . TRP A 1 294 ? 136.625 196.603 161.444 1.00 106.39 ? 305 TRP A CE3  1 
ATOM   4445 C  CZ2  . TRP A 1 294 ? 135.542 194.985 159.390 1.00 105.67 ? 305 TRP A CZ2  1 
ATOM   4446 C  CZ3  . TRP A 1 294 ? 137.017 195.287 161.279 1.00 104.59 ? 305 TRP A CZ3  1 
ATOM   4447 C  CH2  . TRP A 1 294 ? 136.476 194.493 160.260 1.00 106.66 ? 305 TRP A CH2  1 
ATOM   4448 H  H    . TRP A 1 294 ? 135.257 201.248 163.109 1.00 104.37 ? 305 TRP A H    1 
ATOM   4449 H  HA   . TRP A 1 294 ? 133.378 200.309 161.570 1.00 104.51 ? 305 TRP A HA   1 
ATOM   4450 H  HB2  . TRP A 1 294 ? 135.497 200.365 160.720 1.00 104.91 ? 305 TRP A HB2  1 
ATOM   4451 H  HB3  . TRP A 1 294 ? 136.038 199.426 161.882 1.00 104.94 ? 305 TRP A HB3  1 
ATOM   4452 H  HD1  . TRP A 1 294 ? 133.650 199.011 159.074 1.00 104.29 ? 305 TRP A HD1  1 
ATOM   4453 H  HE1  . TRP A 1 294 ? 133.787 196.783 158.172 1.00 104.48 ? 305 TRP A HE1  1 
ATOM   4454 H  HE3  . TRP A 1 294 ? 136.990 197.124 162.123 1.00 104.66 ? 305 TRP A HE3  1 
ATOM   4455 H  HZ2  . TRP A 1 294 ? 135.185 194.455 158.715 1.00 105.14 ? 305 TRP A HZ2  1 
ATOM   4456 H  HZ3  . TRP A 1 294 ? 137.650 194.923 161.854 1.00 104.61 ? 305 TRP A HZ3  1 
ATOM   4457 H  HH2  . TRP A 1 294 ? 136.758 193.611 160.173 1.00 105.31 ? 305 TRP A HH2  1 
ATOM   4458 N  N    . MET A 1 295 ? 134.212 198.322 163.944 1.00 112.63 ? 306 MET A N    1 
ATOM   4459 C  CA   . MET A 1 295 ? 133.731 197.162 164.687 1.00 111.54 ? 306 MET A CA   1 
ATOM   4460 C  C    . MET A 1 295 ? 132.335 197.402 165.246 1.00 110.94 ? 306 MET A C    1 
ATOM   4461 O  O    . MET A 1 295 ? 131.547 196.459 165.374 1.00 107.39 ? 306 MET A O    1 
ATOM   4462 C  CB   . MET A 1 295 ? 134.705 196.815 165.812 1.00 110.14 ? 306 MET A CB   1 
ATOM   4463 C  CG   . MET A 1 295 ? 135.952 196.087 165.340 1.00 111.61 ? 306 MET A CG   1 
ATOM   4464 S  SD   . MET A 1 295 ? 135.613 194.366 164.917 1.00 113.51 ? 306 MET A SD   1 
ATOM   4465 C  CE   . MET A 1 295 ? 137.263 193.672 164.930 1.00 112.17 ? 306 MET A CE   1 
ATOM   4466 H  H    . MET A 1 295 ? 134.928 198.681 164.255 1.00 110.21 ? 306 MET A H    1 
ATOM   4467 H  HA   . MET A 1 295 ? 133.695 196.402 164.084 1.00 110.85 ? 306 MET A HA   1 
ATOM   4468 H  HB2  . MET A 1 295 ? 134.986 197.635 166.247 1.00 110.40 ? 306 MET A HB2  1 
ATOM   4469 H  HB3  . MET A 1 295 ? 134.252 196.242 166.452 1.00 110.66 ? 306 MET A HB3  1 
ATOM   4470 H  HG2  . MET A 1 295 ? 136.299 196.529 164.549 1.00 110.55 ? 306 MET A HG2  1 
ATOM   4471 H  HG3  . MET A 1 295 ? 136.615 196.098 166.048 1.00 110.97 ? 306 MET A HG3  1 
ATOM   4472 H  HE1  . MET A 1 295 ? 137.750 194.003 164.160 1.00 110.91 ? 306 MET A HE1  1 
ATOM   4473 H  HE2  . MET A 1 295 ? 137.712 193.938 165.747 1.00 110.83 ? 306 MET A HE2  1 
ATOM   4474 H  HE3  . MET A 1 295 ? 137.198 192.705 164.887 1.00 111.25 ? 306 MET A HE3  1 
ATOM   4475 N  N    . GLU A 1 296 ? 132.013 198.649 165.578 1.00 117.74 ? 307 GLU A N    1 
ATOM   4476 C  CA   . GLU A 1 296 ? 130.687 199.008 166.049 1.00 115.48 ? 307 GLU A CA   1 
ATOM   4477 C  C    . GLU A 1 296 ? 129.828 199.471 164.873 1.00 113.15 ? 307 GLU A C    1 
ATOM   4478 O  O    . GLU A 1 296 ? 130.250 199.455 163.714 1.00 113.03 ? 307 GLU A O    1 
ATOM   4479 C  CB   . GLU A 1 296 ? 130.782 200.091 167.124 1.00 116.20 ? 307 GLU A CB   1 
ATOM   4480 C  CG   . GLU A 1 296 ? 131.469 199.636 168.401 1.00 116.16 ? 307 GLU A CG   1 
ATOM   4481 C  CD   . GLU A 1 296 ? 130.658 198.608 169.166 1.00 115.02 ? 307 GLU A CD   1 
ATOM   4482 O  OE1  . GLU A 1 296 ? 129.524 198.930 169.578 1.00 115.86 ? 307 GLU A OE1  1 
ATOM   4483 O  OE2  . GLU A 1 296 ? 131.155 197.478 169.354 1.00 115.48 ? 307 GLU A OE2  1 
ATOM   4484 H  H    . GLU A 1 296 ? 132.557 199.314 165.537 1.00 115.26 ? 307 GLU A H    1 
ATOM   4485 H  HA   . GLU A 1 296 ? 130.264 198.229 166.442 1.00 114.94 ? 307 GLU A HA   1 
ATOM   4486 H  HB2  . GLU A 1 296 ? 131.285 200.840 166.768 1.00 115.24 ? 307 GLU A HB2  1 
ATOM   4487 H  HB3  . GLU A 1 296 ? 129.886 200.379 167.358 1.00 115.34 ? 307 GLU A HB3  1 
ATOM   4488 H  HG2  . GLU A 1 296 ? 132.324 199.237 168.176 1.00 115.41 ? 307 GLU A HG2  1 
ATOM   4489 H  HG3  . GLU A 1 296 ? 131.602 200.404 168.979 1.00 115.39 ? 307 GLU A HG3  1 
ATOM   4490 N  N    . GLU A 1 297 ? 128.603 199.891 165.176 1.00 121.99 ? 308 GLU A N    1 
ATOM   4491 C  CA   . GLU A 1 297 ? 127.675 200.394 164.173 1.00 124.53 ? 308 GLU A CA   1 
ATOM   4492 C  C    . GLU A 1 297 ? 127.740 201.909 164.023 1.00 124.94 ? 308 GLU A C    1 
ATOM   4493 O  O    . GLU A 1 297 ? 126.910 202.485 163.312 1.00 126.35 ? 308 GLU A O    1 
ATOM   4494 C  CB   . GLU A 1 297 ? 126.245 199.972 164.523 1.00 126.76 ? 308 GLU A CB   1 
ATOM   4495 C  CG   . GLU A 1 297 ? 125.992 198.477 164.409 1.00 126.95 ? 308 GLU A CG   1 
ATOM   4496 C  CD   . GLU A 1 297 ? 126.084 197.976 162.981 1.00 127.04 ? 308 GLU A CD   1 
ATOM   4497 O  OE1  . GLU A 1 297 ? 125.274 198.421 162.141 1.00 126.25 ? 308 GLU A OE1  1 
ATOM   4498 O  OE2  . GLU A 1 297 ? 126.965 197.137 162.699 1.00 125.32 ? 308 GLU A OE2  1 
ATOM   4499 H  H    . GLU A 1 297 ? 128.280 199.892 165.973 1.00 124.55 ? 308 GLU A H    1 
ATOM   4500 H  HA   . GLU A 1 297 ? 127.899 200.003 163.314 1.00 124.80 ? 308 GLU A HA   1 
ATOM   4501 H  HB2  . GLU A 1 297 ? 126.058 200.235 165.438 1.00 125.32 ? 308 GLU A HB2  1 
ATOM   4502 H  HB3  . GLU A 1 297 ? 125.632 200.422 163.921 1.00 125.34 ? 308 GLU A HB3  1 
ATOM   4503 H  HG2  . GLU A 1 297 ? 126.654 198.004 164.937 1.00 125.31 ? 308 GLU A HG2  1 
ATOM   4504 H  HG3  . GLU A 1 297 ? 125.102 198.281 164.740 1.00 125.21 ? 308 GLU A HG3  1 
ATOM   4505 N  N    . LYS A 1 298 ? 128.703 202.566 164.674 1.00 113.00 ? 309 LYS A N    1 
ATOM   4506 C  CA   . LYS A 1 298 ? 128.783 204.021 164.599 1.00 113.31 ? 309 LYS A CA   1 
ATOM   4507 C  C    . LYS A 1 298 ? 129.025 204.486 163.170 1.00 113.89 ? 309 LYS A C    1 
ATOM   4508 O  O    . LYS A 1 298 ? 128.417 205.462 162.714 1.00 115.94 ? 309 LYS A O    1 
ATOM   4509 C  CB   . LYS A 1 298 ? 129.890 204.532 165.522 1.00 110.67 ? 309 LYS A CB   1 
ATOM   4510 H  H    . LYS A 1 298 ? 129.312 202.198 165.157 1.00 113.20 ? 309 LYS A H    1 
ATOM   4511 H  HA   . LYS A 1 298 ? 127.942 204.400 164.900 1.00 113.55 ? 309 LYS A HA   1 
ATOM   4512 N  N    . VAL A 1 299 ? 129.905 203.803 162.449 1.00 101.93 ? 310 VAL A N    1 
ATOM   4513 C  CA   . VAL A 1 299 ? 130.236 204.142 161.067 1.00 102.48 ? 310 VAL A CA   1 
ATOM   4514 C  C    . VAL A 1 299 ? 129.521 203.154 160.153 1.00 104.56 ? 310 VAL A C    1 
ATOM   4515 O  O    . VAL A 1 299 ? 129.764 201.942 160.263 1.00 105.76 ? 310 VAL A O    1 
ATOM   4516 C  CB   . VAL A 1 299 ? 131.753 204.120 160.828 1.00 101.36 ? 310 VAL A CB   1 
ATOM   4517 C  CG1  . VAL A 1 299 ? 132.307 202.710 160.972 1.00 101.36 ? 310 VAL A CG1  1 
ATOM   4518 C  CG2  . VAL A 1 299 ? 132.074 204.680 159.456 1.00 102.16 ? 310 VAL A CG2  1 
ATOM   4519 H  H    . VAL A 1 299 ? 130.335 203.121 162.746 1.00 103.07 ? 310 VAL A H    1 
ATOM   4520 H  HA   . VAL A 1 299 ? 129.923 205.039 160.878 1.00 103.16 ? 310 VAL A HA   1 
ATOM   4521 H  HB   . VAL A 1 299 ? 132.186 204.681 161.490 1.00 102.89 ? 310 VAL A HB   1 
ATOM   4522 H  HG11 . VAL A 1 299 ? 133.245 202.764 161.212 1.00 102.99 ? 310 VAL A HG11 1 
ATOM   4523 H  HG12 . VAL A 1 299 ? 131.817 202.243 161.666 1.00 103.08 ? 310 VAL A HG12 1 
ATOM   4524 H  HG13 . VAL A 1 299 ? 132.206 202.244 160.128 1.00 102.79 ? 310 VAL A HG13 1 
ATOM   4525 H  HG21 . VAL A 1 299 ? 133.037 204.742 159.358 1.00 102.82 ? 310 VAL A HG21 1 
ATOM   4526 H  HG22 . VAL A 1 299 ? 131.710 204.089 158.779 1.00 102.26 ? 310 VAL A HG22 1 
ATOM   4527 H  HG23 . VAL A 1 299 ? 131.677 205.562 159.374 1.00 102.39 ? 310 VAL A HG23 1 
ATOM   4528 N  N    . PRO A 1 300 ? 128.626 203.605 159.267 1.00 112.04 ? 311 PRO A N    1 
ATOM   4529 C  CA   . PRO A 1 300 ? 128.002 202.653 158.331 1.00 112.74 ? 311 PRO A CA   1 
ATOM   4530 C  C    . PRO A 1 300 ? 129.016 201.893 157.492 1.00 112.28 ? 311 PRO A C    1 
ATOM   4531 O  O    . PRO A 1 300 ? 128.980 200.657 157.448 1.00 110.02 ? 311 PRO A O    1 
ATOM   4532 C  CB   . PRO A 1 300 ? 127.097 203.549 157.473 1.00 112.42 ? 311 PRO A CB   1 
ATOM   4533 C  CG   . PRO A 1 300 ? 126.837 204.752 158.304 1.00 111.46 ? 311 PRO A CG   1 
ATOM   4534 C  CD   . PRO A 1 300 ? 128.058 204.959 159.145 1.00 111.04 ? 311 PRO A CD   1 
ATOM   4535 H  HA   . PRO A 1 300 ? 127.453 202.018 158.817 1.00 110.01 ? 311 PRO A HA   1 
ATOM   4536 H  HB2  . PRO A 1 300 ? 127.559 203.792 156.656 1.00 109.97 ? 311 PRO A HB2  1 
ATOM   4537 H  HB3  . PRO A 1 300 ? 126.271 203.083 157.274 1.00 110.10 ? 311 PRO A HB3  1 
ATOM   4538 H  HG2  . PRO A 1 300 ? 126.690 205.517 157.727 1.00 109.64 ? 311 PRO A HG2  1 
ATOM   4539 H  HG3  . PRO A 1 300 ? 126.062 204.596 158.865 1.00 110.03 ? 311 PRO A HG3  1 
ATOM   4540 H  HD2  . PRO A 1 300 ? 128.683 205.545 158.693 1.00 109.30 ? 311 PRO A HD2  1 
ATOM   4541 H  HD3  . PRO A 1 300 ? 127.812 205.304 160.017 1.00 109.80 ? 311 PRO A HD3  1 
ATOM   4542 N  N    . VAL A 1 301 ? 129.922 202.601 156.821 1.00 101.67 ? 312 VAL A N    1 
ATOM   4543 C  CA   . VAL A 1 301 ? 130.961 201.988 156.003 1.00 96.84  ? 312 VAL A CA   1 
ATOM   4544 C  C    . VAL A 1 301 ? 132.288 202.642 156.351 1.00 95.92  ? 312 VAL A C    1 
ATOM   4545 O  O    . VAL A 1 301 ? 132.390 203.874 156.377 1.00 91.99  ? 312 VAL A O    1 
ATOM   4546 C  CB   . VAL A 1 301 ? 130.666 202.129 154.497 1.00 99.06  ? 312 VAL A CB   1 
ATOM   4547 C  CG1  . VAL A 1 301 ? 130.643 203.595 154.088 1.00 98.62  ? 312 VAL A CG1  1 
ATOM   4548 C  CG2  . VAL A 1 301 ? 131.692 201.357 153.676 1.00 101.19 ? 312 VAL A CG2  1 
ATOM   4549 H  H    . VAL A 1 301 ? 129.954 203.460 156.825 1.00 99.02  ? 312 VAL A H    1 
ATOM   4550 H  HA   . VAL A 1 301 ? 131.023 201.043 156.213 1.00 98.16  ? 312 VAL A HA   1 
ATOM   4551 H  HB   . VAL A 1 301 ? 129.791 201.754 154.311 1.00 98.76  ? 312 VAL A HB   1 
ATOM   4552 H  HG11 . VAL A 1 301 ? 130.231 203.671 153.213 1.00 98.16  ? 312 VAL A HG11 1 
ATOM   4553 H  HG12 . VAL A 1 301 ? 130.129 204.096 154.740 1.00 98.22  ? 312 VAL A HG12 1 
ATOM   4554 H  HG13 . VAL A 1 301 ? 131.552 203.929 154.056 1.00 98.26  ? 312 VAL A HG13 1 
ATOM   4555 H  HG21 . VAL A 1 301 ? 131.524 201.516 152.734 1.00 98.71  ? 312 VAL A HG21 1 
ATOM   4556 H  HG22 . VAL A 1 301 ? 132.583 201.662 153.906 1.00 98.72  ? 312 VAL A HG22 1 
ATOM   4557 H  HG23 . VAL A 1 301 ? 131.604 200.412 153.872 1.00 98.79  ? 312 VAL A HG23 1 
ATOM   4558 N  N    . ILE A 1 302 ? 133.298 201.823 156.617 1.00 100.08 ? 313 ILE A N    1 
ATOM   4559 C  CA   . ILE A 1 302 ? 134.635 202.309 156.934 1.00 102.25 ? 313 ILE A CA   1 
ATOM   4560 C  C    . ILE A 1 302 ? 135.454 202.364 155.655 1.00 95.82  ? 313 ILE A C    1 
ATOM   4561 O  O    . ILE A 1 302 ? 135.202 201.632 154.692 1.00 94.82  ? 313 ILE A O    1 
ATOM   4562 C  CB   . ILE A 1 302 ? 135.315 201.423 158.001 1.00 103.40 ? 313 ILE A CB   1 
ATOM   4563 C  CG1  . ILE A 1 302 ? 136.345 202.233 158.793 1.00 101.69 ? 313 ILE A CG1  1 
ATOM   4564 C  CG2  . ILE A 1 302 ? 135.986 200.217 157.356 1.00 98.94  ? 313 ILE A CG2  1 
ATOM   4565 C  CD1  . ILE A 1 302 ? 135.742 203.161 159.825 1.00 99.13  ? 313 ILE A CD1  1 
ATOM   4566 H  H    . ILE A 1 302 ? 133.233 200.965 156.619 1.00 99.83  ? 313 ILE A H    1 
ATOM   4567 H  HA   . ILE A 1 302 ? 134.569 203.209 157.287 1.00 99.96  ? 313 ILE A HA   1 
ATOM   4568 H  HB   . ILE A 1 302 ? 134.635 201.105 158.615 1.00 100.41 ? 313 ILE A HB   1 
ATOM   4569 H  HG12 . ILE A 1 302 ? 136.934 201.618 159.257 1.00 99.96  ? 313 ILE A HG12 1 
ATOM   4570 H  HG13 . ILE A 1 302 ? 136.859 202.775 158.174 1.00 99.79  ? 313 ILE A HG13 1 
ATOM   4571 H  HG21 . ILE A 1 302 ? 136.214 199.577 158.048 1.00 99.31  ? 313 ILE A HG21 1 
ATOM   4572 H  HG22 . ILE A 1 302 ? 135.372 199.814 156.722 1.00 99.94  ? 313 ILE A HG22 1 
ATOM   4573 H  HG23 . ILE A 1 302 ? 136.794 200.503 156.901 1.00 99.35  ? 313 ILE A HG23 1 
ATOM   4574 H  HD11 . ILE A 1 302 ? 135.355 202.629 160.537 1.00 99.90  ? 313 ILE A HD11 1 
ATOM   4575 H  HD12 . ILE A 1 302 ? 136.442 203.730 160.182 1.00 99.46  ? 313 ILE A HD12 1 
ATOM   4576 H  HD13 . ILE A 1 302 ? 135.058 203.704 159.406 1.00 99.36  ? 313 ILE A HD13 1 
ATOM   4577 N  N    . VAL A 1 303 ? 136.447 203.246 155.648 1.00 84.03  ? 314 VAL A N    1 
ATOM   4578 C  CA   . VAL A 1 303 ? 137.369 203.404 154.532 1.00 79.96  ? 314 VAL A CA   1 
ATOM   4579 C  C    . VAL A 1 303 ? 138.771 203.109 155.045 1.00 84.88  ? 314 VAL A C    1 
ATOM   4580 O  O    . VAL A 1 303 ? 139.194 203.669 156.062 1.00 86.54  ? 314 VAL A O    1 
ATOM   4581 C  CB   . VAL A 1 303 ? 137.284 204.817 153.926 1.00 86.61  ? 314 VAL A CB   1 
ATOM   4582 C  CG1  . VAL A 1 303 ? 138.317 204.998 152.840 1.00 89.66  ? 314 VAL A CG1  1 
ATOM   4583 C  CG2  . VAL A 1 303 ? 135.890 205.074 153.377 1.00 86.95  ? 314 VAL A CG2  1 
ATOM   4584 H  H    . VAL A 1 303 ? 136.612 203.780 156.301 1.00 88.64  ? 314 VAL A H    1 
ATOM   4585 H  HA   . VAL A 1 303 ? 137.156 202.760 153.839 1.00 86.68  ? 314 VAL A HA   1 
ATOM   4586 H  HB   . VAL A 1 303 ? 137.461 205.474 154.616 1.00 88.74  ? 314 VAL A HB   1 
ATOM   4587 H  HG11 . VAL A 1 303 ? 138.249 205.898 152.488 1.00 88.95  ? 314 VAL A HG11 1 
ATOM   4588 H  HG12 . VAL A 1 303 ? 139.192 204.863 153.225 1.00 88.80  ? 314 VAL A HG12 1 
ATOM   4589 H  HG13 . VAL A 1 303 ? 138.157 204.350 152.136 1.00 88.29  ? 314 VAL A HG13 1 
ATOM   4590 H  HG21 . VAL A 1 303 ? 135.810 206.015 153.152 1.00 88.39  ? 314 VAL A HG21 1 
ATOM   4591 H  HG22 . VAL A 1 303 ? 135.758 204.532 152.584 1.00 87.67  ? 314 VAL A HG22 1 
ATOM   4592 H  HG23 . VAL A 1 303 ? 135.237 204.839 154.052 1.00 88.61  ? 314 VAL A HG23 1 
ATOM   4593 N  N    . ALA A 1 304 ? 139.484 202.230 154.344 1.00 92.62  ? 315 ALA A N    1 
ATOM   4594 C  CA   . ALA A 1 304 ? 140.811 201.801 154.761 1.00 93.61  ? 315 ALA A CA   1 
ATOM   4595 C  C    . ALA A 1 304 ? 141.722 201.721 153.545 1.00 92.15  ? 315 ALA A C    1 
ATOM   4596 O  O    . ALA A 1 304 ? 141.271 201.737 152.398 1.00 94.92  ? 315 ALA A O    1 
ATOM   4597 C  CB   . ALA A 1 304 ? 140.760 200.448 155.482 1.00 93.57  ? 315 ALA A CB   1 
ATOM   4598 H  H    . ALA A 1 304 ? 139.216 201.864 153.614 1.00 92.72  ? 315 ALA A H    1 
ATOM   4599 H  HA   . ALA A 1 304 ? 141.180 202.456 155.374 1.00 93.43  ? 315 ALA A HA   1 
ATOM   4600 H  HB1  . ALA A 1 304 ? 141.659 200.197 155.746 1.00 93.50  ? 315 ALA A HB1  1 
ATOM   4601 H  HB2  . ALA A 1 304 ? 140.195 200.529 156.267 1.00 93.55  ? 315 ALA A HB2  1 
ATOM   4602 H  HB3  . ALA A 1 304 ? 140.394 199.783 154.878 1.00 92.45  ? 315 ALA A HB3  1 
ATOM   4603 N  N    . THR A 1 305 ? 143.024 201.646 153.812 1.00 86.11  ? 316 THR A N    1 
ATOM   4604 C  CA   . THR A 1 305 ? 144.014 201.492 152.758 1.00 83.23  ? 316 THR A CA   1 
ATOM   4605 C  C    . THR A 1 305 ? 144.140 200.020 152.372 1.00 83.70  ? 316 THR A C    1 
ATOM   4606 O  O    . THR A 1 305 ? 143.417 199.154 152.872 1.00 83.86  ? 316 THR A O    1 
ATOM   4607 C  CB   . THR A 1 305 ? 145.360 202.062 153.201 1.00 85.00  ? 316 THR A CB   1 
ATOM   4608 O  OG1  . THR A 1 305 ? 146.272 202.056 152.096 1.00 89.70  ? 316 THR A OG1  1 
ATOM   4609 C  CG2  . THR A 1 305 ? 145.948 201.246 154.348 1.00 83.93  ? 316 THR A CG2  1 
ATOM   4610 H  H    . THR A 1 305 ? 143.358 201.682 154.603 1.00 87.54  ? 316 THR A H    1 
ATOM   4611 H  HA   . THR A 1 305 ? 143.723 201.982 151.975 1.00 86.66  ? 316 THR A HA   1 
ATOM   4612 H  HB   . THR A 1 305 ? 145.237 202.973 153.509 1.00 87.18  ? 316 THR A HB   1 
ATOM   4613 H  HG1  . THR A 1 305 ? 147.021 202.349 152.339 1.00 87.21  ? 316 THR A HG1  1 
ATOM   4614 H  HG21 . THR A 1 305 ? 146.759 201.670 154.671 1.00 86.62  ? 316 THR A HG21 1 
ATOM   4615 H  HG22 . THR A 1 305 ? 145.312 201.188 155.078 1.00 86.68  ? 316 THR A HG22 1 
ATOM   4616 H  HG23 . THR A 1 305 ? 146.164 200.350 154.048 1.00 86.07  ? 316 THR A HG23 1 
ATOM   4617 N  N    . ILE A 1 306 ? 145.076 199.731 151.465 1.00 87.28  ? 317 ILE A N    1 
ATOM   4618 C  CA   . ILE A 1 306 ? 145.264 198.355 151.015 1.00 90.75  ? 317 ILE A CA   1 
ATOM   4619 C  C    . ILE A 1 306 ? 145.570 197.450 152.202 1.00 86.59  ? 317 ILE A C    1 
ATOM   4620 O  O    . ILE A 1 306 ? 145.062 196.326 152.292 1.00 84.12  ? 317 ILE A O    1 
ATOM   4621 C  CB   . ILE A 1 306 ? 146.368 198.288 149.941 1.00 89.25  ? 317 ILE A CB   1 
ATOM   4622 C  CG1  . ILE A 1 306 ? 146.317 196.950 149.200 1.00 85.41  ? 317 ILE A CG1  1 
ATOM   4623 C  CG2  . ILE A 1 306 ? 147.743 198.500 150.560 1.00 84.47  ? 317 ILE A CG2  1 
ATOM   4624 C  CD1  . ILE A 1 306 ? 145.178 196.843 148.205 1.00 84.61  ? 317 ILE A CD1  1 
ATOM   4625 H  H    . ILE A 1 306 ? 145.605 200.303 151.102 1.00 86.46  ? 317 ILE A H    1 
ATOM   4626 H  HA   . ILE A 1 306 ? 144.439 198.044 150.612 1.00 86.22  ? 317 ILE A HA   1 
ATOM   4627 H  HB   . ILE A 1 306 ? 146.211 198.998 149.299 1.00 86.38  ? 317 ILE A HB   1 
ATOM   4628 H  HG12 . ILE A 1 306 ? 147.147 196.833 148.711 1.00 85.28  ? 317 ILE A HG12 1 
ATOM   4629 H  HG13 . ILE A 1 306 ? 146.214 196.235 149.847 1.00 85.61  ? 317 ILE A HG13 1 
ATOM   4630 H  HG21 . ILE A 1 306 ? 148.381 198.680 149.852 1.00 85.31  ? 317 ILE A HG21 1 
ATOM   4631 H  HG22 . ILE A 1 306 ? 147.702 199.254 151.168 1.00 85.73  ? 317 ILE A HG22 1 
ATOM   4632 H  HG23 . ILE A 1 306 ? 148.002 197.699 151.041 1.00 85.49  ? 317 ILE A HG23 1 
ATOM   4633 H  HD11 . ILE A 1 306 ? 145.238 195.990 147.748 1.00 85.73  ? 317 ILE A HD11 1 
ATOM   4634 H  HD12 . ILE A 1 306 ? 144.335 196.904 148.680 1.00 85.50  ? 317 ILE A HD12 1 
ATOM   4635 H  HD13 . ILE A 1 306 ? 145.250 197.567 147.564 1.00 85.21  ? 317 ILE A HD13 1 
ATOM   4636 N  N    . SER A 1 307 ? 146.399 197.922 153.127 1.00 72.41  ? 318 SER A N    1 
ATOM   4637 C  CA   . SER A 1 307 ? 146.613 197.216 154.379 1.00 69.79  ? 318 SER A CA   1 
ATOM   4638 C  C    . SER A 1 307 ? 145.410 197.406 155.294 1.00 68.82  ? 318 SER A C    1 
ATOM   4639 O  O    . SER A 1 307 ? 144.739 198.441 155.266 1.00 68.40  ? 318 SER A O    1 
ATOM   4640 C  CB   . SER A 1 307 ? 147.881 197.715 155.071 1.00 70.00  ? 318 SER A CB   1 
ATOM   4641 O  OG   . SER A 1 307 ? 147.742 199.065 155.479 1.00 66.09  ? 318 SER A OG   1 
ATOM   4642 H  H    . SER A 1 307 ? 146.852 198.649 153.050 1.00 72.65  ? 318 SER A H    1 
ATOM   4643 H  HA   . SER A 1 307 ? 146.715 196.268 154.201 1.00 71.60  ? 318 SER A HA   1 
ATOM   4644 H  HB2  . SER A 1 307 ? 148.051 197.166 155.852 1.00 70.72  ? 318 SER A HB2  1 
ATOM   4645 H  HB3  . SER A 1 307 ? 148.625 197.649 154.452 1.00 71.51  ? 318 SER A HB3  1 
ATOM   4646 H  HG   . SER A 1 307 ? 148.452 199.331 155.840 1.00 70.54  ? 318 SER A HG   1 
ATOM   4647 N  N    . PHE A 1 308 ? 145.139 196.389 156.105 1.00 77.53  ? 319 PHE A N    1 
ATOM   4648 C  CA   . PHE A 1 308 ? 143.987 196.412 156.999 1.00 78.41  ? 319 PHE A CA   1 
ATOM   4649 C  C    . PHE A 1 308 ? 143.988 197.668 157.862 1.00 76.41  ? 319 PHE A C    1 
ATOM   4650 O  O    . PHE A 1 308 ? 142.941 198.268 158.097 1.00 78.99  ? 319 PHE A O    1 
ATOM   4651 C  CB   . PHE A 1 308 ? 143.974 195.170 157.890 1.00 79.97  ? 319 PHE A CB   1 
ATOM   4652 C  CG   . PHE A 1 308 ? 142.793 195.102 158.812 1.00 77.88  ? 319 PHE A CG   1 
ATOM   4653 C  CD1  . PHE A 1 308 ? 141.543 194.750 158.332 1.00 78.08  ? 319 PHE A CD1  1 
ATOM   4654 C  CD2  . PHE A 1 308 ? 142.930 195.395 160.159 1.00 82.29  ? 319 PHE A CD2  1 
ATOM   4655 C  CE1  . PHE A 1 308 ? 140.452 194.688 159.179 1.00 83.08  ? 319 PHE A CE1  1 
ATOM   4656 C  CE2  . PHE A 1 308 ? 141.843 195.335 161.010 1.00 82.58  ? 319 PHE A CE2  1 
ATOM   4657 C  CZ   . PHE A 1 308 ? 140.603 194.981 160.520 1.00 83.33  ? 319 PHE A CZ   1 
ATOM   4658 H  H    . PHE A 1 308 ? 145.608 195.671 156.157 1.00 79.27  ? 319 PHE A H    1 
ATOM   4659 H  HA   . PHE A 1 308 ? 143.175 196.411 156.470 1.00 79.55  ? 319 PHE A HA   1 
ATOM   4660 H  HB2  . PHE A 1 308 ? 143.957 194.381 157.326 1.00 80.17  ? 319 PHE A HB2  1 
ATOM   4661 H  HB3  . PHE A 1 308 ? 144.776 195.167 158.435 1.00 80.17  ? 319 PHE A HB3  1 
ATOM   4662 H  HD1  . PHE A 1 308 ? 141.436 194.551 157.430 1.00 79.44  ? 319 PHE A HD1  1 
ATOM   4663 H  HD2  . PHE A 1 308 ? 143.764 195.633 160.494 1.00 80.55  ? 319 PHE A HD2  1 
ATOM   4664 H  HE1  . PHE A 1 308 ? 139.617 194.450 158.846 1.00 80.73  ? 319 PHE A HE1  1 
ATOM   4665 H  HE2  . PHE A 1 308 ? 141.948 195.533 161.913 1.00 80.23  ? 319 PHE A HE2  1 
ATOM   4666 H  HZ   . PHE A 1 308 ? 139.870 194.940 161.091 1.00 80.96  ? 319 PHE A HZ   1 
ATOM   4667 N  N    . ASP A 1 313 ? 138.670 192.010 160.977 1.00 103.65 ? 324 ASP A N    1 
ATOM   4668 C  CA   . ASP A 1 313 ? 137.625 191.038 160.683 1.00 104.55 ? 324 ASP A CA   1 
ATOM   4669 C  C    . ASP A 1 313 ? 136.371 191.323 161.504 1.00 103.75 ? 324 ASP A C    1 
ATOM   4670 O  O    . ASP A 1 313 ? 136.455 191.691 162.675 1.00 106.68 ? 324 ASP A O    1 
ATOM   4671 C  CB   . ASP A 1 313 ? 138.122 189.617 160.960 1.00 105.32 ? 324 ASP A CB   1 
ATOM   4672 H  H    . ASP A 1 313 ? 138.669 192.694 160.455 1.00 103.61 ? 324 ASP A H    1 
ATOM   4673 H  HA   . ASP A 1 313 ? 137.390 191.098 159.744 1.00 104.02 ? 324 ASP A HA   1 
ATOM   4674 N  N    . LYS A 1 314 ? 135.210 191.147 160.878 1.00 100.51 ? 325 LYS A N    1 
ATOM   4675 C  CA   . LYS A 1 314 ? 133.926 191.378 161.521 1.00 103.98 ? 325 LYS A CA   1 
ATOM   4676 C  C    . LYS A 1 314 ? 133.034 190.162 161.321 1.00 106.34 ? 325 LYS A C    1 
ATOM   4677 O  O    . LYS A 1 314 ? 133.177 189.420 160.346 1.00 104.64 ? 325 LYS A O    1 
ATOM   4678 C  CB   . LYS A 1 314 ? 133.235 192.630 160.962 1.00 105.83 ? 325 LYS A CB   1 
ATOM   4679 C  CG   . LYS A 1 314 ? 131.974 193.034 161.713 1.00 105.29 ? 325 LYS A CG   1 
ATOM   4680 C  CD   . LYS A 1 314 ? 131.488 194.408 161.282 1.00 103.90 ? 325 LYS A CD   1 
ATOM   4681 C  CE   . LYS A 1 314 ? 130.231 194.817 162.034 1.00 102.65 ? 325 LYS A CE   1 
ATOM   4682 N  NZ   . LYS A 1 314 ? 129.024 194.100 161.538 1.00 101.55 ? 325 LYS A NZ   1 
ATOM   4683 H  H    . LYS A 1 314 ? 135.142 190.889 160.061 1.00 103.60 ? 325 LYS A H    1 
ATOM   4684 H  HA   . LYS A 1 314 ? 134.058 191.504 162.473 1.00 104.10 ? 325 LYS A HA   1 
ATOM   4685 H  HB2  . LYS A 1 314 ? 133.855 193.374 161.006 1.00 104.28 ? 325 LYS A HB2  1 
ATOM   4686 H  HB3  . LYS A 1 314 ? 132.988 192.464 160.039 1.00 104.41 ? 325 LYS A HB3  1 
ATOM   4687 H  HG2  . LYS A 1 314 ? 131.272 192.391 161.529 1.00 104.00 ? 325 LYS A HG2  1 
ATOM   4688 H  HG3  . LYS A 1 314 ? 132.163 193.062 162.664 1.00 104.22 ? 325 LYS A HG3  1 
ATOM   4689 H  HD2  . LYS A 1 314 ? 132.178 195.064 161.465 1.00 104.02 ? 325 LYS A HD2  1 
ATOM   4690 H  HD3  . LYS A 1 314 ? 131.282 194.393 160.334 1.00 103.99 ? 325 LYS A HD3  1 
ATOM   4691 H  HE2  . LYS A 1 314 ? 130.341 194.609 162.975 1.00 104.09 ? 325 LYS A HE2  1 
ATOM   4692 H  HE3  . LYS A 1 314 ? 130.086 195.769 161.917 1.00 104.00 ? 325 LYS A HE3  1 
ATOM   4693 H  HZ1  . LYS A 1 314 ? 129.129 193.222 161.638 1.00 103.96 ? 325 LYS A HZ1  1 
ATOM   4694 H  HZ2  . LYS A 1 314 ? 128.307 194.359 161.997 1.00 103.84 ? 325 LYS A HZ2  1 
ATOM   4695 H  HZ3  . LYS A 1 314 ? 128.896 194.280 160.676 1.00 103.85 ? 325 LYS A HZ3  1 
ATOM   4696 N  N    . ALA A 1 315 ? 132.108 189.964 162.262 1.00 114.53 ? 326 ALA A N    1 
ATOM   4697 C  CA   . ALA A 1 315 ? 131.201 188.825 162.171 1.00 115.02 ? 326 ALA A CA   1 
ATOM   4698 C  C    . ALA A 1 315 ? 130.359 188.896 160.904 1.00 113.59 ? 326 ALA A C    1 
ATOM   4699 O  O    . ALA A 1 315 ? 130.169 187.885 160.218 1.00 111.68 ? 326 ALA A O    1 
ATOM   4700 C  CB   . ALA A 1 315 ? 130.306 188.768 163.408 1.00 113.45 ? 326 ALA A CB   1 
ATOM   4701 H  H    . ALA A 1 315 ? 131.988 190.466 162.950 1.00 112.52 ? 326 ALA A H    1 
ATOM   4702 H  HA   . ALA A 1 315 ? 131.722 188.008 162.140 1.00 113.10 ? 326 ALA A HA   1 
ATOM   4703 H  HB1  . ALA A 1 315 ? 129.711 188.006 163.333 1.00 113.06 ? 326 ALA A HB1  1 
ATOM   4704 H  HB2  . ALA A 1 315 ? 130.863 188.677 164.197 1.00 112.85 ? 326 ALA A HB2  1 
ATOM   4705 H  HB3  . ALA A 1 315 ? 129.790 189.588 163.462 1.00 112.76 ? 326 ALA A HB3  1 
ATOM   4706 N  N    . ASN A 1 316 ? 129.846 190.080 160.579 1.00 108.34 ? 327 ASN A N    1 
ATOM   4707 C  CA   . ASN A 1 316 ? 129.043 190.280 159.381 1.00 106.66 ? 327 ASN A CA   1 
ATOM   4708 C  C    . ASN A 1 316 ? 129.484 191.563 158.698 1.00 104.57 ? 327 ASN A C    1 
ATOM   4709 O  O    . ASN A 1 316 ? 129.560 192.615 159.339 1.00 104.76 ? 327 ASN A O    1 
ATOM   4710 C  CB   . ASN A 1 316 ? 127.548 190.346 159.719 1.00 109.91 ? 327 ASN A CB   1 
ATOM   4711 C  CG   . ASN A 1 316 ? 127.237 191.377 160.786 1.00 109.17 ? 327 ASN A CG   1 
ATOM   4712 O  OD1  . ASN A 1 316 ? 127.443 191.139 161.976 1.00 109.31 ? 327 ASN A OD1  1 
ATOM   4713 N  ND2  . ASN A 1 316 ? 126.735 192.532 160.364 1.00 107.84 ? 327 ASN A ND2  1 
ATOM   4714 H  H    . ASN A 1 316 ? 129.951 190.794 161.046 1.00 107.61 ? 327 ASN A H    1 
ATOM   4715 H  HA   . ASN A 1 316 ? 129.185 189.543 158.766 1.00 107.12 ? 327 ASN A HA   1 
ATOM   4716 H  HB2  . ASN A 1 316 ? 127.052 190.581 158.920 1.00 108.01 ? 327 ASN A HB2  1 
ATOM   4717 H  HB3  . ASN A 1 316 ? 127.259 189.480 160.047 1.00 107.95 ? 327 ASN A HB3  1 
ATOM   4718 H  HD21 . ASN A 1 316 ? 126.604 192.663 159.524 1.00 107.73 ? 327 ASN A HD21 1 
ATOM   4719 H  HD22 . ASN A 1 316 ? 126.542 193.149 160.930 1.00 107.59 ? 327 ASN A HD22 1 
ATOM   4720 N  N    . VAL A 1 317 ? 129.771 191.471 157.402 1.00 92.44  ? 328 VAL A N    1 
ATOM   4721 C  CA   . VAL A 1 317 ? 130.174 192.610 156.587 1.00 92.72  ? 328 VAL A CA   1 
ATOM   4722 C  C    . VAL A 1 317 ? 129.209 192.718 155.417 1.00 97.18  ? 328 VAL A C    1 
ATOM   4723 O  O    . VAL A 1 317 ? 128.959 191.728 154.720 1.00 97.54  ? 328 VAL A O    1 
ATOM   4724 C  CB   . VAL A 1 317 ? 131.624 192.469 156.090 1.00 93.97  ? 328 VAL A CB   1 
ATOM   4725 C  CG1  . VAL A 1 317 ? 131.943 193.538 155.057 1.00 94.94  ? 328 VAL A CG1  1 
ATOM   4726 C  CG2  . VAL A 1 317 ? 132.592 192.546 157.259 1.00 95.66  ? 328 VAL A CG2  1 
ATOM   4727 H  H    . VAL A 1 317 ? 129.737 190.734 156.960 1.00 95.64  ? 328 VAL A H    1 
ATOM   4728 H  HA   . VAL A 1 317 ? 130.110 193.422 157.113 1.00 95.55  ? 328 VAL A HA   1 
ATOM   4729 H  HB   . VAL A 1 317 ? 131.727 191.601 155.671 1.00 96.12  ? 328 VAL A HB   1 
ATOM   4730 H  HG11 . VAL A 1 317 ? 132.891 193.505 154.860 1.00 96.02  ? 328 VAL A HG11 1 
ATOM   4731 H  HG12 . VAL A 1 317 ? 131.439 193.366 154.246 1.00 96.03  ? 328 VAL A HG12 1 
ATOM   4732 H  HG13 . VAL A 1 317 ? 131.708 194.407 155.417 1.00 95.89  ? 328 VAL A HG13 1 
ATOM   4733 H  HG21 . VAL A 1 317 ? 133.499 192.471 156.923 1.00 96.14  ? 328 VAL A HG21 1 
ATOM   4734 H  HG22 . VAL A 1 317 ? 132.474 193.396 157.710 1.00 96.37  ? 328 VAL A HG22 1 
ATOM   4735 H  HG23 . VAL A 1 317 ? 132.404 191.817 157.872 1.00 96.44  ? 328 VAL A HG23 1 
ATOM   4736 N  N    . ARG A 1 318 ? 128.673 193.919 155.202 1.00 111.59 ? 329 ARG A N    1 
ATOM   4737 C  CA   . ARG A 1 318 ? 127.687 194.108 154.145 1.00 113.46 ? 329 ARG A CA   1 
ATOM   4738 C  C    . ARG A 1 318 ? 128.333 194.113 152.765 1.00 109.76 ? 329 ARG A C    1 
ATOM   4739 O  O    . ARG A 1 318 ? 127.755 193.586 151.808 1.00 109.78 ? 329 ARG A O    1 
ATOM   4740 C  CB   . ARG A 1 318 ? 126.914 195.407 154.377 1.00 114.82 ? 329 ARG A CB   1 
ATOM   4741 C  CG   . ARG A 1 318 ? 126.144 195.444 155.693 1.00 115.12 ? 329 ARG A CG   1 
ATOM   4742 C  CD   . ARG A 1 318 ? 124.748 194.853 155.550 1.00 116.39 ? 329 ARG A CD   1 
ATOM   4743 N  NE   . ARG A 1 318 ? 124.789 193.448 155.162 1.00 118.47 ? 329 ARG A NE   1 
ATOM   4744 C  CZ   . ARG A 1 318 ? 125.181 192.460 155.955 1.00 116.19 ? 329 ARG A CZ   1 
ATOM   4745 N  NH1  . ARG A 1 318 ? 125.543 192.681 157.208 1.00 117.11 ? 329 ARG A NH1  1 
ATOM   4746 N  NH2  . ARG A 1 318 ? 125.215 191.220 155.477 1.00 112.17 ? 329 ARG A NH2  1 
ATOM   4747 H  H    . ARG A 1 318 ? 128.861 194.629 155.648 1.00 111.39 ? 329 ARG A H    1 
ATOM   4748 H  HA   . ARG A 1 318 ? 127.059 193.371 154.169 1.00 112.72 ? 329 ARG A HA   1 
ATOM   4749 H  HB2  . ARG A 1 318 ? 127.541 196.147 154.381 1.00 112.72 ? 329 ARG A HB2  1 
ATOM   4750 H  HB3  . ARG A 1 318 ? 126.275 195.523 153.657 1.00 112.56 ? 329 ARG A HB3  1 
ATOM   4751 H  HG2  . ARG A 1 318 ? 126.624 194.931 156.361 1.00 112.52 ? 329 ARG A HG2  1 
ATOM   4752 H  HG3  . ARG A 1 318 ? 126.054 196.366 155.981 1.00 112.42 ? 329 ARG A HG3  1 
ATOM   4753 H  HD2  . ARG A 1 318 ? 124.287 194.917 156.401 1.00 112.94 ? 329 ARG A HD2  1 
ATOM   4754 H  HD3  . ARG A 1 318 ? 124.261 195.342 154.869 1.00 113.11 ? 329 ARG A HD3  1 
ATOM   4755 H  HE   . ARG A 1 318 ? 124.503 193.241 154.377 1.00 113.39 ? 329 ARG A HE   1 
ATOM   4756 H  HH11 . ARG A 1 318 ? 125.526 193.477 157.528 1.00 113.06 ? 329 ARG A HH11 1 
ATOM   4757 H  HH12 . ARG A 1 318 ? 125.793 192.024 157.704 1.00 113.18 ? 329 ARG A HH12 1 
ATOM   4758 H  HH21 . ARG A 1 318 ? 125.467 190.573 155.984 1.00 112.66 ? 329 ARG A HH21 1 
ATOM   4759 H  HH22 . ARG A 1 318 ? 124.983 191.065 154.664 1.00 112.44 ? 329 ARG A HH22 1 
ATOM   4760 N  N    . PHE A 1 319 ? 129.521 194.697 152.637 1.00 94.20  ? 330 PHE A N    1 
ATOM   4761 C  CA   . PHE A 1 319 ? 130.163 194.804 151.334 1.00 89.48  ? 330 PHE A CA   1 
ATOM   4762 C  C    . PHE A 1 319 ? 131.618 195.204 151.518 1.00 89.60  ? 330 PHE A C    1 
ATOM   4763 O  O    . PHE A 1 319 ? 132.007 195.754 152.552 1.00 94.31  ? 330 PHE A O    1 
ATOM   4764 C  CB   . PHE A 1 319 ? 129.442 195.817 150.440 1.00 89.54  ? 330 PHE A CB   1 
ATOM   4765 C  CG   . PHE A 1 319 ? 129.437 197.210 150.991 1.00 90.19  ? 330 PHE A CG   1 
ATOM   4766 C  CD1  . PHE A 1 319 ? 128.569 197.562 152.011 1.00 95.36  ? 330 PHE A CD1  1 
ATOM   4767 C  CD2  . PHE A 1 319 ? 130.304 198.167 150.497 1.00 87.57  ? 330 PHE A CD2  1 
ATOM   4768 C  CE1  . PHE A 1 319 ? 128.562 198.843 152.522 1.00 94.48  ? 330 PHE A CE1  1 
ATOM   4769 C  CE2  . PHE A 1 319 ? 130.303 199.448 151.005 1.00 92.34  ? 330 PHE A CE2  1 
ATOM   4770 C  CZ   . PHE A 1 319 ? 129.430 199.787 152.019 1.00 95.07  ? 330 PHE A CZ   1 
ATOM   4771 H  H    . PHE A 1 319 ? 129.973 195.037 153.286 1.00 94.50  ? 330 PHE A H    1 
ATOM   4772 H  HA   . PHE A 1 319 ? 130.138 193.939 150.898 1.00 93.27  ? 330 PHE A HA   1 
ATOM   4773 H  HB2  . PHE A 1 319 ? 129.883 195.845 149.578 1.00 93.13  ? 330 PHE A HB2  1 
ATOM   4774 H  HB3  . PHE A 1 319 ? 128.519 195.537 150.330 1.00 93.59  ? 330 PHE A HB3  1 
ATOM   4775 H  HD1  . PHE A 1 319 ? 127.981 196.928 152.352 1.00 94.66  ? 330 PHE A HD1  1 
ATOM   4776 H  HD2  . PHE A 1 319 ? 130.894 197.943 149.813 1.00 92.49  ? 330 PHE A HD2  1 
ATOM   4777 H  HE1  . PHE A 1 319 ? 127.974 199.068 153.205 1.00 94.29  ? 330 PHE A HE1  1 
ATOM   4778 H  HE2  . PHE A 1 319 ? 130.889 200.084 150.664 1.00 93.44  ? 330 PHE A HE2  1 
ATOM   4779 H  HZ   . PHE A 1 319 ? 129.428 200.651 152.362 1.00 94.17  ? 330 PHE A HZ   1 
ATOM   4780 N  N    . VAL A 1 320 ? 132.416 194.919 150.493 1.00 79.74  ? 331 VAL A N    1 
ATOM   4781 C  CA   . VAL A 1 320 ? 133.821 195.306 150.439 1.00 82.49  ? 331 VAL A CA   1 
ATOM   4782 C  C    . VAL A 1 320 ? 134.068 195.898 149.060 1.00 77.91  ? 331 VAL A C    1 
ATOM   4783 O  O    . VAL A 1 320 ? 134.072 195.171 148.059 1.00 83.21  ? 331 VAL A O    1 
ATOM   4784 C  CB   . VAL A 1 320 ? 134.765 194.127 150.707 1.00 83.78  ? 331 VAL A CB   1 
ATOM   4785 C  CG1  . VAL A 1 320 ? 136.175 194.457 150.238 1.00 82.71  ? 331 VAL A CG1  1 
ATOM   4786 C  CG2  . VAL A 1 320 ? 134.772 193.782 152.188 1.00 83.32  ? 331 VAL A CG2  1 
ATOM   4787 H  H    . VAL A 1 320 ? 132.156 194.489 149.795 1.00 82.89  ? 331 VAL A H    1 
ATOM   4788 H  HA   . VAL A 1 320 ? 133.993 195.993 151.102 1.00 83.96  ? 331 VAL A HA   1 
ATOM   4789 H  HB   . VAL A 1 320 ? 134.455 193.350 150.215 1.00 82.47  ? 331 VAL A HB   1 
ATOM   4790 H  HG11 . VAL A 1 320 ? 136.799 193.855 150.674 1.00 82.59  ? 331 VAL A HG11 1 
ATOM   4791 H  HG12 . VAL A 1 320 ? 136.227 194.343 149.276 1.00 82.58  ? 331 VAL A HG12 1 
ATOM   4792 H  HG13 . VAL A 1 320 ? 136.382 195.374 150.478 1.00 82.82  ? 331 VAL A HG13 1 
ATOM   4793 H  HG21 . VAL A 1 320 ? 135.035 192.855 152.293 1.00 82.64  ? 331 VAL A HG21 1 
ATOM   4794 H  HG22 . VAL A 1 320 ? 135.406 194.359 152.643 1.00 82.73  ? 331 VAL A HG22 1 
ATOM   4795 H  HG23 . VAL A 1 320 ? 133.882 193.916 152.549 1.00 83.37  ? 331 VAL A HG23 1 
ATOM   4796 N  N    . ALA A 1 321 ? 134.270 197.209 149.006 1.00 66.22  ? 332 ALA A N    1 
ATOM   4797 C  CA   . ALA A 1 321 ? 134.518 197.915 147.760 1.00 63.88  ? 332 ALA A CA   1 
ATOM   4798 C  C    . ALA A 1 321 ? 136.003 198.211 147.624 1.00 58.79  ? 332 ALA A C    1 
ATOM   4799 O  O    . ALA A 1 321 ? 136.683 198.504 148.612 1.00 70.30  ? 332 ALA A O    1 
ATOM   4800 C  CB   . ALA A 1 321 ? 133.718 199.218 147.701 1.00 69.78  ? 332 ALA A CB   1 
ATOM   4801 H  H    . ALA A 1 321 ? 134.269 197.722 149.696 1.00 71.97  ? 332 ALA A H    1 
ATOM   4802 H  HA   . ALA A 1 321 ? 134.247 197.359 147.013 1.00 70.07  ? 332 ALA A HA   1 
ATOM   4803 H  HB1  . ALA A 1 321 ? 133.907 199.666 146.862 1.00 70.17  ? 332 ALA A HB1  1 
ATOM   4804 H  HB2  . ALA A 1 321 ? 132.772 199.010 147.761 1.00 71.25  ? 332 ALA A HB2  1 
ATOM   4805 H  HB3  . ALA A 1 321 ? 133.981 199.783 148.444 1.00 70.85  ? 332 ALA A HB3  1 
ATOM   4806 N  N    . HIS A 1 322 ? 136.503 198.120 146.396 1.00 60.99  ? 333 HIS A N    1 
ATOM   4807 C  CA   . HIS A 1 322 ? 137.898 198.412 146.081 1.00 68.58  ? 333 HIS A CA   1 
ATOM   4808 C  C    . HIS A 1 322 ? 137.915 199.588 145.113 1.00 72.78  ? 333 HIS A C    1 
ATOM   4809 O  O    . HIS A 1 322 ? 137.640 199.422 143.920 1.00 80.40  ? 333 HIS A O    1 
ATOM   4810 C  CB   . HIS A 1 322 ? 138.594 197.192 145.489 1.00 71.45  ? 333 HIS A CB   1 
ATOM   4811 C  CG   . HIS A 1 322 ? 139.036 196.197 146.513 1.00 67.92  ? 333 HIS A CG   1 
ATOM   4812 N  ND1  . HIS A 1 322 ? 138.151 195.396 147.202 1.00 69.74  ? 333 HIS A ND1  1 
ATOM   4813 C  CD2  . HIS A 1 322 ? 140.269 195.875 146.969 1.00 69.41  ? 333 HIS A CD2  1 
ATOM   4814 C  CE1  . HIS A 1 322 ? 138.820 194.622 148.037 1.00 75.57  ? 333 HIS A CE1  1 
ATOM   4815 N  NE2  . HIS A 1 322 ? 140.107 194.892 147.915 1.00 70.65  ? 333 HIS A NE2  1 
ATOM   4816 H  H    . HIS A 1 322 ? 136.041 197.885 145.710 1.00 71.44  ? 333 HIS A H    1 
ATOM   4817 H  HA   . HIS A 1 322 ? 138.368 198.672 146.889 1.00 71.44  ? 333 HIS A HA   1 
ATOM   4818 H  HB2  . HIS A 1 322 ? 137.981 196.745 144.885 1.00 71.76  ? 333 HIS A HB2  1 
ATOM   4819 H  HB3  . HIS A 1 322 ? 139.380 197.486 145.002 1.00 72.04  ? 333 HIS A HB3  1 
ATOM   4820 H  HD2  . HIS A 1 322 ? 141.075 196.248 146.692 1.00 71.63  ? 333 HIS A HD2  1 
ATOM   4821 H  HE1  . HIS A 1 322 ? 138.449 193.993 148.613 1.00 72.93  ? 333 HIS A HE1  1 
ATOM   4822 H  HE2  . HIS A 1 322 ? 140.741 194.515 148.356 1.00 71.41  ? 333 HIS A HE2  1 
ATOM   4823 N  N    . TRP A 1 323 ? 138.235 200.777 145.624 1.00 80.18  ? 334 TRP A N    1 
ATOM   4824 C  CA   . TRP A 1 323 ? 138.302 201.942 144.751 1.00 82.26  ? 334 TRP A CA   1 
ATOM   4825 C  C    . TRP A 1 323 ? 139.369 201.770 143.682 1.00 77.37  ? 334 TRP A C    1 
ATOM   4826 O  O    . TRP A 1 323 ? 139.238 202.315 142.580 1.00 82.35  ? 334 TRP A O    1 
ATOM   4827 C  CB   . TRP A 1 323 ? 138.583 203.205 145.563 1.00 86.52  ? 334 TRP A CB   1 
ATOM   4828 C  CG   . TRP A 1 323 ? 138.563 204.433 144.716 1.00 81.26  ? 334 TRP A CG   1 
ATOM   4829 C  CD1  . TRP A 1 323 ? 139.638 205.136 144.265 1.00 82.43  ? 334 TRP A CD1  1 
ATOM   4830 C  CD2  . TRP A 1 323 ? 137.404 205.100 144.209 1.00 75.48  ? 334 TRP A CD2  1 
ATOM   4831 N  NE1  . TRP A 1 323 ? 139.220 206.202 143.507 1.00 82.72  ? 334 TRP A NE1  1 
ATOM   4832 C  CE2  . TRP A 1 323 ? 137.851 206.202 143.458 1.00 78.44  ? 334 TRP A CE2  1 
ATOM   4833 C  CE3  . TRP A 1 323 ? 136.029 204.873 144.319 1.00 79.62  ? 334 TRP A CE3  1 
ATOM   4834 C  CZ2  . TRP A 1 323 ? 136.975 207.073 142.820 1.00 82.01  ? 334 TRP A CZ2  1 
ATOM   4835 C  CZ3  . TRP A 1 323 ? 135.162 205.737 143.686 1.00 83.45  ? 334 TRP A CZ3  1 
ATOM   4836 C  CH2  . TRP A 1 323 ? 135.637 206.825 142.947 1.00 83.37  ? 334 TRP A CH2  1 
ATOM   4837 H  H    . TRP A 1 323 ? 138.414 200.932 146.451 1.00 81.82  ? 334 TRP A H    1 
ATOM   4838 H  HA   . TRP A 1 323 ? 137.447 202.055 144.307 1.00 82.28  ? 334 TRP A HA   1 
ATOM   4839 H  HB2  . TRP A 1 323 ? 137.904 203.300 146.249 1.00 82.95  ? 334 TRP A HB2  1 
ATOM   4840 H  HB3  . TRP A 1 323 ? 139.460 203.133 145.970 1.00 83.25  ? 334 TRP A HB3  1 
ATOM   4841 H  HD1  . TRP A 1 323 ? 140.526 204.924 144.442 1.00 82.24  ? 334 TRP A HD1  1 
ATOM   4842 H  HE1  . TRP A 1 323 ? 139.734 206.777 143.126 1.00 83.14  ? 334 TRP A HE1  1 
ATOM   4843 H  HE3  . TRP A 1 323 ? 135.706 204.150 144.808 1.00 82.21  ? 334 TRP A HE3  1 
ATOM   4844 H  HZ2  . TRP A 1 323 ? 137.287 207.798 142.329 1.00 83.24  ? 334 TRP A HZ2  1 
ATOM   4845 H  HZ3  . TRP A 1 323 ? 134.245 205.595 143.752 1.00 83.13  ? 334 TRP A HZ3  1 
ATOM   4846 H  HH2  . TRP A 1 323 ? 135.028 207.392 142.531 1.00 83.65  ? 334 TRP A HH2  1 
ATOM   4847 N  N    . ASN A 1 324 ? 140.427 201.024 143.985 1.00 70.70  ? 335 ASN A N    1 
ATOM   4848 C  CA   . ASN A 1 324 ? 141.498 200.762 143.040 1.00 79.59  ? 335 ASN A CA   1 
ATOM   4849 C  C    . ASN A 1 324 ? 141.811 199.273 143.031 1.00 80.58  ? 335 ASN A C    1 
ATOM   4850 O  O    . ASN A 1 324 ? 141.598 198.565 144.018 1.00 86.13  ? 335 ASN A O    1 
ATOM   4851 C  CB   . ASN A 1 324 ? 142.757 201.566 143.386 1.00 77.53  ? 335 ASN A CB   1 
ATOM   4852 C  CG   . ASN A 1 324 ? 142.582 203.052 143.146 1.00 79.05  ? 335 ASN A CG   1 
ATOM   4853 O  OD1  . ASN A 1 324 ? 142.002 203.465 142.143 1.00 79.40  ? 335 ASN A OD1  1 
ATOM   4854 N  ND2  . ASN A 1 324 ? 143.086 203.864 144.067 1.00 81.60  ? 335 ASN A ND2  1 
ATOM   4855 H  H    . ASN A 1 324 ? 140.547 200.651 144.751 1.00 78.28  ? 335 ASN A H    1 
ATOM   4856 H  HA   . ASN A 1 324 ? 141.211 201.016 142.149 1.00 80.10  ? 335 ASN A HA   1 
ATOM   4857 H  HB2  . ASN A 1 324 ? 142.968 201.436 144.324 1.00 79.42  ? 335 ASN A HB2  1 
ATOM   4858 H  HB3  . ASN A 1 324 ? 143.493 201.257 142.834 1.00 79.07  ? 335 ASN A HB3  1 
ATOM   4859 H  HD21 . ASN A 1 324 ? 143.486 203.539 144.756 1.00 80.51  ? 335 ASN A HD21 1 
ATOM   4860 H  HD22 . ASN A 1 324 ? 143.012 204.716 143.976 1.00 79.52  ? 335 ASN A HD22 1 
ATOM   4861 N  N    . ILE A 1 325 ? 142.320 198.805 141.890 1.00 74.27  ? 336 ILE A N    1 
ATOM   4862 C  CA   . ILE A 1 325 ? 142.688 197.402 141.762 1.00 74.08  ? 336 ILE A CA   1 
ATOM   4863 C  C    . ILE A 1 325 ? 143.722 197.051 142.821 1.00 78.59  ? 336 ILE A C    1 
ATOM   4864 O  O    . ILE A 1 325 ? 144.661 197.814 143.080 1.00 81.46  ? 336 ILE A O    1 
ATOM   4865 C  CB   . ILE A 1 325 ? 143.216 197.118 140.346 1.00 84.69  ? 336 ILE A CB   1 
ATOM   4866 C  CG1  . ILE A 1 325 ? 143.471 195.622 140.157 1.00 85.04  ? 336 ILE A CG1  1 
ATOM   4867 C  CG2  . ILE A 1 325 ? 144.491 197.909 140.083 1.00 86.03  ? 336 ILE A CG2  1 
ATOM   4868 C  CD1  . ILE A 1 325 ? 143.777 195.240 138.722 1.00 82.01  ? 336 ILE A CD1  1 
ATOM   4869 H  H    . ILE A 1 325 ? 142.457 199.276 141.184 1.00 80.67  ? 336 ILE A H    1 
ATOM   4870 H  HA   . ILE A 1 325 ? 141.903 196.851 141.910 1.00 80.02  ? 336 ILE A HA   1 
ATOM   4871 H  HB   . ILE A 1 325 ? 142.543 197.398 139.706 1.00 81.91  ? 336 ILE A HB   1 
ATOM   4872 H  HG12 . ILE A 1 325 ? 144.230 195.360 140.701 1.00 82.02  ? 336 ILE A HG12 1 
ATOM   4873 H  HG13 . ILE A 1 325 ? 142.682 195.131 140.434 1.00 81.60  ? 336 ILE A HG13 1 
ATOM   4874 H  HG21 . ILE A 1 325 ? 144.699 197.863 139.137 1.00 81.53  ? 336 ILE A HG21 1 
ATOM   4875 H  HG22 . ILE A 1 325 ? 144.351 198.832 140.344 1.00 81.87  ? 336 ILE A HG22 1 
ATOM   4876 H  HG23 . ILE A 1 325 ? 145.215 197.525 140.600 1.00 82.25  ? 336 ILE A HG23 1 
ATOM   4877 H  HD11 . ILE A 1 325 ? 143.919 194.283 138.669 1.00 81.12  ? 336 ILE A HD11 1 
ATOM   4878 H  HD12 . ILE A 1 325 ? 143.027 195.495 138.163 1.00 81.48  ? 336 ILE A HD12 1 
ATOM   4879 H  HD13 . ILE A 1 325 ? 144.577 195.706 138.435 1.00 81.39  ? 336 ILE A HD13 1 
ATOM   4880 N  N    . ALA A 1 326 ? 143.551 195.888 143.442 1.00 77.45  ? 337 ALA A N    1 
ATOM   4881 C  CA   . ALA A 1 326 ? 144.450 195.482 144.509 1.00 81.80  ? 337 ALA A CA   1 
ATOM   4882 C  C    . ALA A 1 326 ? 145.841 195.191 143.956 1.00 87.16  ? 337 ALA A C    1 
ATOM   4883 O  O    . ALA A 1 326 ? 146.040 195.012 142.751 1.00 91.07  ? 337 ALA A O    1 
ATOM   4884 C  CB   . ALA A 1 326 ? 143.910 194.248 145.228 1.00 82.07  ? 337 ALA A CB   1 
ATOM   4885 H  H    . ALA A 1 326 ? 142.927 195.323 143.265 1.00 81.88  ? 337 ALA A H    1 
ATOM   4886 H  HA   . ALA A 1 326 ? 144.524 196.201 145.155 1.00 83.24  ? 337 ALA A HA   1 
ATOM   4887 H  HB1  . ALA A 1 326 ? 144.437 194.092 146.028 1.00 83.08  ? 337 ALA A HB1  1 
ATOM   4888 H  HB2  . ALA A 1 326 ? 142.982 194.400 145.465 1.00 82.89  ? 337 ALA A HB2  1 
ATOM   4889 H  HB3  . ALA A 1 326 ? 143.981 193.489 144.630 1.00 82.99  ? 337 ALA A HB3  1 
ATOM   4890 N  N    . LYS A 1 327 ? 146.818 195.151 144.864 1.00 85.93  ? 338 LYS A N    1 
ATOM   4891 C  CA   . LYS A 1 327 ? 148.193 194.891 144.452 1.00 83.53  ? 338 LYS A CA   1 
ATOM   4892 C  C    . LYS A 1 327 ? 148.326 193.512 143.820 1.00 86.00  ? 338 LYS A C    1 
ATOM   4893 O  O    . LYS A 1 327 ? 149.017 193.349 142.808 1.00 84.83  ? 338 LYS A O    1 
ATOM   4894 C  CB   . LYS A 1 327 ? 149.132 195.023 145.651 1.00 83.76  ? 338 LYS A CB   1 
ATOM   4895 H  H    . LYS A 1 327 ? 146.712 195.269 145.709 1.00 84.54  ? 338 LYS A H    1 
ATOM   4896 H  HA   . LYS A 1 327 ? 148.455 195.551 143.791 1.00 84.22  ? 338 LYS A HA   1 
ATOM   4897 N  N    . SER A 1 328 ? 147.671 192.508 144.400 1.00 90.08  ? 339 SER A N    1 
ATOM   4898 C  CA   . SER A 1 328 ? 147.730 191.143 143.900 1.00 91.16  ? 339 SER A CA   1 
ATOM   4899 C  C    . SER A 1 328 ? 146.330 190.547 143.869 1.00 84.77  ? 339 SER A C    1 
ATOM   4900 O  O    . SER A 1 328 ? 145.465 190.907 144.671 1.00 80.50  ? 339 SER A O    1 
ATOM   4901 C  CB   . SER A 1 328 ? 148.648 190.269 144.766 1.00 89.83  ? 339 SER A CB   1 
ATOM   4902 O  OG   . SER A 1 328 ? 148.199 190.230 146.109 1.00 82.48  ? 339 SER A OG   1 
ATOM   4903 H  H    . SER A 1 328 ? 147.178 192.598 145.098 1.00 86.26  ? 339 SER A H    1 
ATOM   4904 H  HA   . SER A 1 328 ? 148.078 191.145 142.995 1.00 86.75  ? 339 SER A HA   1 
ATOM   4905 H  HB2  . SER A 1 328 ? 148.653 189.367 144.409 1.00 86.47  ? 339 SER A HB2  1 
ATOM   4906 H  HB3  . SER A 1 328 ? 149.545 190.637 144.744 1.00 86.48  ? 339 SER A HB3  1 
ATOM   4907 H  HG   . SER A 1 328 ? 148.715 189.755 146.571 1.00 85.21  ? 339 SER A HG   1 
ATOM   4908 N  N    . MET A 1 329 ? 146.119 189.625 142.928 1.00 81.16  ? 340 MET A N    1 
ATOM   4909 C  CA   . MET A 1 329 ? 144.818 188.976 142.805 1.00 79.75  ? 340 MET A CA   1 
ATOM   4910 C  C    . MET A 1 329 ? 144.465 188.232 144.085 1.00 74.13  ? 340 MET A C    1 
ATOM   4911 O  O    . MET A 1 329 ? 143.335 188.322 144.583 1.00 76.18  ? 340 MET A O    1 
ATOM   4912 C  CB   . MET A 1 329 ? 144.829 188.025 141.607 1.00 82.74  ? 340 MET A CB   1 
ATOM   4913 C  CG   . MET A 1 329 ? 143.732 186.978 141.620 1.00 81.79  ? 340 MET A CG   1 
ATOM   4914 S  SD   . MET A 1 329 ? 142.087 187.687 141.760 1.00 81.53  ? 340 MET A SD   1 
ATOM   4915 C  CE   . MET A 1 329 ? 141.120 186.200 141.975 1.00 76.71  ? 340 MET A CE   1 
ATOM   4916 H  H    . MET A 1 329 ? 146.706 189.361 142.358 1.00 79.37  ? 340 MET A H    1 
ATOM   4917 H  HA   . MET A 1 329 ? 144.146 189.655 142.643 1.00 78.97  ? 340 MET A HA   1 
ATOM   4918 H  HB2  . MET A 1 329 ? 144.727 188.540 140.793 1.00 79.40  ? 340 MET A HB2  1 
ATOM   4919 H  HB3  . MET A 1 329 ? 145.679 187.558 141.592 1.00 79.29  ? 340 MET A HB3  1 
ATOM   4920 H  HG2  . MET A 1 329 ? 143.770 186.476 140.791 1.00 79.13  ? 340 MET A HG2  1 
ATOM   4921 H  HG3  . MET A 1 329 ? 143.864 186.383 142.372 1.00 79.41  ? 340 MET A HG3  1 
ATOM   4922 H  HE1  . MET A 1 329 ? 140.183 186.441 141.993 1.00 78.30  ? 340 MET A HE1  1 
ATOM   4923 H  HE2  . MET A 1 329 ? 141.294 185.600 141.233 1.00 78.71  ? 340 MET A HE2  1 
ATOM   4924 H  HE3  . MET A 1 329 ? 141.372 185.776 142.811 1.00 78.42  ? 340 MET A HE3  1 
ATOM   4925 N  N    . ALA A 1 330 ? 145.426 187.490 144.637 1.00 70.82  ? 341 ALA A N    1 
ATOM   4926 C  CA   . ALA A 1 330 ? 145.207 186.852 145.928 1.00 72.16  ? 341 ALA A CA   1 
ATOM   4927 C  C    . ALA A 1 330 ? 144.937 187.896 147.000 1.00 72.71  ? 341 ALA A C    1 
ATOM   4928 O  O    . ALA A 1 330 ? 144.100 187.688 147.885 1.00 72.72  ? 341 ALA A O    1 
ATOM   4929 C  CB   . ALA A 1 330 ? 146.413 185.992 146.302 1.00 74.65  ? 341 ALA A CB   1 
ATOM   4930 H  H    . ALA A 1 330 ? 146.199 187.344 144.289 1.00 73.86  ? 341 ALA A H    1 
ATOM   4931 H  HA   . ALA A 1 330 ? 144.431 186.273 145.868 1.00 73.00  ? 341 ALA A HA   1 
ATOM   4932 H  HB1  . ALA A 1 330 ? 146.250 185.576 147.163 1.00 73.55  ? 341 ALA A HB1  1 
ATOM   4933 H  HB2  . ALA A 1 330 ? 146.537 185.311 145.623 1.00 73.71  ? 341 ALA A HB2  1 
ATOM   4934 H  HB3  . ALA A 1 330 ? 147.200 186.557 146.351 1.00 73.85  ? 341 ALA A HB3  1 
ATOM   4935 N  N    . GLY A 1 331 ? 145.644 189.025 146.940 1.00 81.03  ? 342 GLY A N    1 
ATOM   4936 C  CA   . GLY A 1 331 ? 145.361 190.107 147.866 1.00 82.59  ? 342 GLY A CA   1 
ATOM   4937 C  C    . GLY A 1 331 ? 143.941 190.620 147.734 1.00 82.92  ? 342 GLY A C    1 
ATOM   4938 O  O    . GLY A 1 331 ? 143.270 190.882 148.736 1.00 81.77  ? 342 GLY A O    1 
ATOM   4939 H  H    . GLY A 1 331 ? 146.279 189.183 146.382 1.00 81.33  ? 342 GLY A H    1 
ATOM   4940 H  HA2  . GLY A 1 331 ? 145.494 189.798 148.776 1.00 81.96  ? 342 GLY A HA2  1 
ATOM   4941 H  HA3  . GLY A 1 331 ? 145.971 190.843 147.699 1.00 81.58  ? 342 GLY A HA3  1 
ATOM   4942 N  N    . TYR A 1 332 ? 143.461 190.768 146.497 1.00 85.53  ? 343 TYR A N    1 
ATOM   4943 C  CA   . TYR A 1 332 ? 142.084 191.207 146.298 1.00 86.77  ? 343 TYR A CA   1 
ATOM   4944 C  C    . TYR A 1 332 ? 141.101 190.200 146.875 1.00 84.00  ? 343 TYR A C    1 
ATOM   4945 O  O    . TYR A 1 332 ? 140.119 190.582 147.522 1.00 88.20  ? 343 TYR A O    1 
ATOM   4946 C  CB   . TYR A 1 332 ? 141.797 191.424 144.813 1.00 86.74  ? 343 TYR A CB   1 
ATOM   4947 C  CG   . TYR A 1 332 ? 140.354 191.777 144.533 1.00 86.11  ? 343 TYR A CG   1 
ATOM   4948 C  CD1  . TYR A 1 332 ? 139.851 193.030 144.859 1.00 87.09  ? 343 TYR A CD1  1 
ATOM   4949 C  CD2  . TYR A 1 332 ? 139.493 190.858 143.948 1.00 83.60  ? 343 TYR A CD2  1 
ATOM   4950 C  CE1  . TYR A 1 332 ? 138.533 193.358 144.610 1.00 84.48  ? 343 TYR A CE1  1 
ATOM   4951 C  CE2  . TYR A 1 332 ? 138.173 191.178 143.693 1.00 85.67  ? 343 TYR A CE2  1 
ATOM   4952 C  CZ   . TYR A 1 332 ? 137.699 192.430 144.025 1.00 85.37  ? 343 TYR A CZ   1 
ATOM   4953 O  OH   . TYR A 1 332 ? 136.385 192.754 143.774 1.00 83.41  ? 343 TYR A OH   1 
ATOM   4954 H  H    . TYR A 1 332 ? 143.902 190.625 145.773 1.00 84.00  ? 343 TYR A H    1 
ATOM   4955 H  HA   . TYR A 1 332 ? 141.952 192.052 146.756 1.00 84.70  ? 343 TYR A HA   1 
ATOM   4956 H  HB2  . TYR A 1 332 ? 142.347 192.148 144.483 1.00 84.64  ? 343 TYR A HB2  1 
ATOM   4957 H  HB3  . TYR A 1 332 ? 142.003 190.608 144.332 1.00 84.51  ? 343 TYR A HB3  1 
ATOM   4958 H  HD1  . TYR A 1 332 ? 140.412 193.658 145.253 1.00 84.63  ? 343 TYR A HD1  1 
ATOM   4959 H  HD2  . TYR A 1 332 ? 139.811 190.014 143.723 1.00 84.16  ? 343 TYR A HD2  1 
ATOM   4960 H  HE1  . TYR A 1 332 ? 138.211 194.202 144.832 1.00 83.48  ? 343 TYR A HE1  1 
ATOM   4961 H  HE2  . TYR A 1 332 ? 137.607 190.553 143.300 1.00 84.72  ? 343 TYR A HE2  1 
ATOM   4962 H  HH   . TYR A 1 332 ? 135.991 192.102 143.421 1.00 83.74  ? 343 TYR A HH   1 
ATOM   4963 N  N    . TYR A 1 333 ? 141.341 188.907 146.648 1.00 72.17  ? 344 TYR A N    1 
ATOM   4964 C  CA   . TYR A 1 333 ? 140.433 187.902 147.191 1.00 69.16  ? 344 TYR A CA   1 
ATOM   4965 C  C    . TYR A 1 333 ? 140.435 187.932 148.712 1.00 75.99  ? 344 TYR A C    1 
ATOM   4966 O  O    . TYR A 1 333 ? 139.380 187.817 149.343 1.00 79.25  ? 344 TYR A O    1 
ATOM   4967 C  CB   . TYR A 1 333 ? 140.810 186.506 146.697 1.00 74.51  ? 344 TYR A CB   1 
ATOM   4968 C  CG   . TYR A 1 333 ? 140.075 185.407 147.434 1.00 72.92  ? 344 TYR A CG   1 
ATOM   4969 C  CD1  . TYR A 1 333 ? 140.586 184.859 148.604 1.00 71.78  ? 344 TYR A CD1  1 
ATOM   4970 C  CD2  . TYR A 1 333 ? 138.864 184.924 146.962 1.00 74.94  ? 344 TYR A CD2  1 
ATOM   4971 C  CE1  . TYR A 1 333 ? 139.911 183.862 149.280 1.00 72.83  ? 344 TYR A CE1  1 
ATOM   4972 C  CE2  . TYR A 1 333 ? 138.183 183.925 147.629 1.00 78.36  ? 344 TYR A CE2  1 
ATOM   4973 C  CZ   . TYR A 1 333 ? 138.711 183.397 148.787 1.00 78.34  ? 344 TYR A CZ   1 
ATOM   4974 O  OH   . TYR A 1 333 ? 138.035 182.402 149.454 1.00 80.33  ? 344 TYR A OH   1 
ATOM   4975 H  H    . TYR A 1 333 ? 142.003 188.595 146.197 1.00 75.63  ? 344 TYR A H    1 
ATOM   4976 H  HA   . TYR A 1 333 ? 139.532 188.094 146.888 1.00 74.56  ? 344 TYR A HA   1 
ATOM   4977 H  HB2  . TYR A 1 333 ? 140.591 186.435 145.755 1.00 75.50  ? 344 TYR A HB2  1 
ATOM   4978 H  HB3  . TYR A 1 333 ? 141.761 186.371 146.829 1.00 75.75  ? 344 TYR A HB3  1 
ATOM   4979 H  HD1  . TYR A 1 333 ? 141.395 185.171 148.940 1.00 74.80  ? 344 TYR A HD1  1 
ATOM   4980 H  HD2  . TYR A 1 333 ? 138.504 185.278 146.180 1.00 74.96  ? 344 TYR A HD2  1 
ATOM   4981 H  HE1  . TYR A 1 333 ? 140.266 183.503 150.061 1.00 74.89  ? 344 TYR A HE1  1 
ATOM   4982 H  HE2  . TYR A 1 333 ? 137.373 183.611 147.298 1.00 75.62  ? 344 TYR A HE2  1 
ATOM   4983 H  HH   . TYR A 1 333 ? 138.453 182.187 150.150 1.00 75.13  ? 344 TYR A HH   1 
ATOM   4984 N  N    . GLN A 1 334 ? 141.615 188.066 149.321 1.00 83.13  ? 345 GLN A N    1 
ATOM   4985 C  CA   . GLN A 1 334 ? 141.686 188.109 150.777 1.00 80.32  ? 345 GLN A CA   1 
ATOM   4986 C  C    . GLN A 1 334 ? 140.968 189.334 151.324 1.00 83.23  ? 345 GLN A C    1 
ATOM   4987 O  O    . GLN A 1 334 ? 140.249 189.247 152.326 1.00 86.25  ? 345 GLN A O    1 
ATOM   4988 C  CB   . GLN A 1 334 ? 143.146 188.093 151.233 1.00 80.48  ? 345 GLN A CB   1 
ATOM   4989 C  CG   . GLN A 1 334 ? 143.878 186.793 150.934 1.00 81.19  ? 345 GLN A CG   1 
ATOM   4990 C  CD   . GLN A 1 334 ? 143.275 185.602 151.653 1.00 81.50  ? 345 GLN A CD   1 
ATOM   4991 O  OE1  . GLN A 1 334 ? 142.659 184.735 151.033 1.00 81.54  ? 345 GLN A OE1  1 
ATOM   4992 N  NE2  . GLN A 1 334 ? 143.450 185.554 152.968 1.00 83.31  ? 345 GLN A NE2  1 
ATOM   4993 H  H    . GLN A 1 334 ? 142.373 188.135 148.921 1.00 81.44  ? 345 GLN A H    1 
ATOM   4994 H  HA   . GLN A 1 334 ? 141.248 187.322 151.137 1.00 81.24  ? 345 GLN A HA   1 
ATOM   4995 H  HB2  . GLN A 1 334 ? 143.620 188.809 150.783 1.00 81.57  ? 345 GLN A HB2  1 
ATOM   4996 H  HB3  . GLN A 1 334 ? 143.174 188.233 152.192 1.00 81.48  ? 345 GLN A HB3  1 
ATOM   4997 H  HG2  . GLN A 1 334 ? 143.836 186.617 149.982 1.00 81.54  ? 345 GLN A HG2  1 
ATOM   4998 H  HG3  . GLN A 1 334 ? 144.802 186.879 151.216 1.00 81.47  ? 345 GLN A HG3  1 
ATOM   4999 H  HE21 . GLN A 1 334 ? 143.886 186.179 153.367 1.00 81.56  ? 345 GLN A HE21 1 
ATOM   5000 H  HE22 . GLN A 1 334 ? 143.127 184.898 153.421 1.00 81.87  ? 345 GLN A HE22 1 
ATOM   5001 N  N    . GLU A 1 335 ? 141.151 190.487 150.679 1.00 79.41  ? 346 GLU A N    1 
ATOM   5002 C  CA   . GLU A 1 335 ? 140.477 191.700 151.129 1.00 80.87  ? 346 GLU A CA   1 
ATOM   5003 C  C    . GLU A 1 335 ? 138.966 191.580 150.977 1.00 78.80  ? 346 GLU A C    1 
ATOM   5004 O  O    . GLU A 1 335 ? 138.211 192.054 151.834 1.00 83.33  ? 346 GLU A O    1 
ATOM   5005 C  CB   . GLU A 1 335 ? 141.006 192.905 150.355 1.00 79.79  ? 346 GLU A CB   1 
ATOM   5006 C  CG   . GLU A 1 335 ? 142.450 193.254 150.683 1.00 83.10  ? 346 GLU A CG   1 
ATOM   5007 C  CD   . GLU A 1 335 ? 142.973 194.417 149.865 1.00 87.39  ? 346 GLU A CD   1 
ATOM   5008 O  OE1  . GLU A 1 335 ? 142.255 194.875 148.951 1.00 83.11  ? 346 GLU A OE1  1 
ATOM   5009 O  OE2  . GLU A 1 335 ? 144.102 194.875 150.136 1.00 88.62  ? 346 GLU A OE2  1 
ATOM   5010 H  H    . GLU A 1 335 ? 141.653 190.591 149.989 1.00 80.99  ? 346 GLU A H    1 
ATOM   5011 H  HA   . GLU A 1 335 ? 140.672 191.837 152.069 1.00 81.63  ? 346 GLU A HA   1 
ATOM   5012 H  HB2  . GLU A 1 335 ? 140.956 192.712 149.406 1.00 80.89  ? 346 GLU A HB2  1 
ATOM   5013 H  HB3  . GLU A 1 335 ? 140.458 193.677 150.563 1.00 81.17  ? 346 GLU A HB3  1 
ATOM   5014 H  HG2  . GLU A 1 335 ? 142.509 193.498 151.620 1.00 81.38  ? 346 GLU A HG2  1 
ATOM   5015 H  HG3  . GLU A 1 335 ? 143.012 192.485 150.506 1.00 81.64  ? 346 GLU A HG3  1 
ATOM   5016 N  N    . SER A 1 336 ? 138.504 190.952 149.896 1.00 64.30  ? 347 SER A N    1 
ATOM   5017 C  CA   . SER A 1 336 ? 137.077 190.780 149.669 1.00 67.79  ? 347 SER A CA   1 
ATOM   5018 C  C    . SER A 1 336 ? 136.479 189.652 150.497 1.00 68.89  ? 347 SER A C    1 
ATOM   5019 O  O    . SER A 1 336 ? 135.251 189.574 150.610 1.00 71.86  ? 347 SER A O    1 
ATOM   5020 C  CB   . SER A 1 336 ? 136.819 190.516 148.183 1.00 73.34  ? 347 SER A CB   1 
ATOM   5021 O  OG   . SER A 1 336 ? 137.183 189.193 147.831 1.00 77.77  ? 347 SER A OG   1 
ATOM   5022 H  H    . SER A 1 336 ? 139.002 190.615 149.281 1.00 72.94  ? 347 SER A H    1 
ATOM   5023 H  HA   . SER A 1 336 ? 136.618 191.601 149.909 1.00 72.67  ? 347 SER A HA   1 
ATOM   5024 H  HB2  . SER A 1 336 ? 135.878 190.644 147.997 1.00 73.20  ? 347 SER A HB2  1 
ATOM   5025 H  HB3  . SER A 1 336 ? 137.347 191.138 147.658 1.00 73.37  ? 347 SER A HB3  1 
ATOM   5026 H  HG   . SER A 1 336 ? 137.990 189.054 148.021 1.00 73.65  ? 347 SER A HG   1 
ATOM   5027 N  N    . GLY A 1 337 ? 137.309 188.781 151.073 1.00 71.78  ? 348 GLY A N    1 
ATOM   5028 C  CA   . GLY A 1 337 ? 136.789 187.719 151.916 1.00 74.64  ? 348 GLY A CA   1 
ATOM   5029 C  C    . GLY A 1 337 ? 136.094 188.244 153.151 1.00 80.03  ? 348 GLY A C    1 
ATOM   5030 O  O    . GLY A 1 337 ? 135.137 187.635 153.637 1.00 82.77  ? 348 GLY A O    1 
ATOM   5031 H  H    . GLY A 1 337 ? 138.165 188.788 150.990 1.00 77.08  ? 348 GLY A H    1 
ATOM   5032 H  HA2  . GLY A 1 337 ? 136.149 187.193 151.412 1.00 77.26  ? 348 GLY A HA2  1 
ATOM   5033 H  HA3  . GLY A 1 337 ? 137.514 187.139 152.197 1.00 77.07  ? 348 GLY A HA3  1 
ATOM   5034 N  N    . ARG A 1 338 ? 136.562 189.378 153.676 1.00 93.20  ? 349 ARG A N    1 
ATOM   5035 C  CA   . ARG A 1 338 ? 135.898 189.992 154.817 1.00 94.09  ? 349 ARG A CA   1 
ATOM   5036 C  C    . ARG A 1 338 ? 134.418 190.211 154.534 1.00 93.80  ? 349 ARG A C    1 
ATOM   5037 O  O    . ARG A 1 338 ? 133.579 190.067 155.430 1.00 95.72  ? 349 ARG A O    1 
ATOM   5038 C  CB   . ARG A 1 338 ? 136.580 191.315 155.164 1.00 89.68  ? 349 ARG A CB   1 
ATOM   5039 C  CG   . ARG A 1 338 ? 137.958 191.164 155.771 1.00 90.08  ? 349 ARG A CG   1 
ATOM   5040 C  CD   . ARG A 1 338 ? 138.581 192.513 156.119 1.00 93.92  ? 349 ARG A CD   1 
ATOM   5041 N  NE   . ARG A 1 338 ? 139.914 192.381 156.699 1.00 95.76  ? 349 ARG A NE   1 
ATOM   5042 C  CZ   . ARG A 1 338 ? 141.011 192.111 156.006 1.00 94.19  ? 349 ARG A CZ   1 
ATOM   5043 N  NH1  . ARG A 1 338 ? 140.977 191.950 154.696 1.00 93.11  ? 349 ARG A NH1  1 
ATOM   5044 N  NH2  . ARG A 1 338 ? 142.167 191.971 156.647 1.00 91.91  ? 349 ARG A NH2  1 
ATOM   5045 H  H    . ARG A 1 338 ? 137.253 189.807 153.393 1.00 90.81  ? 349 ARG A H    1 
ATOM   5046 H  HA   . ARG A 1 338 ? 135.969 189.400 155.582 1.00 92.14  ? 349 ARG A HA   1 
ATOM   5047 H  HB2  . ARG A 1 338 ? 136.672 191.838 154.353 1.00 90.97  ? 349 ARG A HB2  1 
ATOM   5048 H  HB3  . ARG A 1 338 ? 136.032 191.780 155.812 1.00 91.76  ? 349 ARG A HB3  1 
ATOM   5049 H  HG2  . ARG A 1 338 ? 137.881 190.652 156.589 1.00 91.94  ? 349 ARG A HG2  1 
ATOM   5050 H  HG3  . ARG A 1 338 ? 138.532 190.717 155.132 1.00 91.12  ? 349 ARG A HG3  1 
ATOM   5051 H  HD2  . ARG A 1 338 ? 138.650 193.043 155.306 1.00 92.35  ? 349 ARG A HD2  1 
ATOM   5052 H  HD3  . ARG A 1 338 ? 138.012 192.948 156.767 1.00 92.09  ? 349 ARG A HD3  1 
ATOM   5053 H  HE   . ARG A 1 338 ? 139.988 192.405 157.554 1.00 92.08  ? 349 ARG A HE   1 
ATOM   5054 H  HH11 . ARG A 1 338 ? 140.241 192.033 154.264 1.00 91.67  ? 349 ARG A HH11 1 
ATOM   5055 H  HH12 . ARG A 1 338 ? 141.703 191.766 154.281 1.00 91.50  ? 349 ARG A HH12 1 
ATOM   5056 H  HH21 . ARG A 1 338 ? 142.208 192.070 157.501 1.00 91.55  ? 349 ARG A HH21 1 
ATOM   5057 H  HH22 . ARG A 1 338 ? 142.882 191.787 156.204 1.00 91.94  ? 349 ARG A HH22 1 
ATOM   5058 N  N    . ALA A 1 339 ? 134.077 190.552 153.295 1.00 88.69  ? 350 ALA A N    1 
ATOM   5059 C  CA   . ALA A 1 339 ? 132.677 190.680 152.921 1.00 87.12  ? 350 ALA A CA   1 
ATOM   5060 C  C    . ALA A 1 339 ? 131.986 189.326 152.980 1.00 87.36  ? 350 ALA A C    1 
ATOM   5061 O  O    . ALA A 1 339 ? 132.578 188.290 152.662 1.00 88.37  ? 350 ALA A O    1 
ATOM   5062 C  CB   . ALA A 1 339 ? 132.548 191.268 151.520 1.00 84.99  ? 350 ALA A CB   1 
ATOM   5063 H  H    . ALA A 1 339 ? 134.632 190.712 152.656 1.00 87.11  ? 350 ALA A H    1 
ATOM   5064 H  HA   . ALA A 1 339 ? 132.233 191.276 153.541 1.00 87.93  ? 350 ALA A HA   1 
ATOM   5065 H  HB1  . ALA A 1 339 ? 131.638 191.140 151.207 1.00 87.26  ? 350 ALA A HB1  1 
ATOM   5066 H  HB2  . ALA A 1 339 ? 132.756 192.213 151.547 1.00 86.72  ? 350 ALA A HB2  1 
ATOM   5067 H  HB3  . ALA A 1 339 ? 133.165 190.801 150.938 1.00 86.78  ? 350 ALA A HB3  1 
ATOM   5068 N  N    . GLY A 1 340 ? 130.722 189.338 153.391 1.00 100.03 ? 351 GLY A N    1 
ATOM   5069 C  CA   . GLY A 1 340 ? 129.965 188.105 153.486 1.00 103.99 ? 351 GLY A CA   1 
ATOM   5070 C  C    . GLY A 1 340 ? 130.531 187.124 154.484 1.00 100.99 ? 351 GLY A C    1 
ATOM   5071 O  O    . GLY A 1 340 ? 130.429 185.910 154.279 1.00 102.59 ? 351 GLY A O    1 
ATOM   5072 H  H    . GLY A 1 340 ? 130.285 190.045 153.616 1.00 100.10 ? 351 GLY A H    1 
ATOM   5073 H  HA2  . GLY A 1 340 ? 129.053 188.309 153.746 1.00 100.92 ? 351 GLY A HA2  1 
ATOM   5074 H  HA3  . GLY A 1 340 ? 129.946 187.677 152.616 1.00 100.89 ? 351 GLY A HA3  1 
ATOM   5075 N  N    . ARG A 1 341 ? 131.128 187.619 155.570 1.00 105.57 ? 352 ARG A N    1 
ATOM   5076 C  CA   . ARG A 1 341 ? 131.616 186.721 156.609 1.00 110.41 ? 352 ARG A CA   1 
ATOM   5077 C  C    . ARG A 1 341 ? 130.469 185.919 157.209 1.00 110.92 ? 352 ARG A C    1 
ATOM   5078 O  O    . ARG A 1 341 ? 130.602 184.714 157.450 1.00 109.80 ? 352 ARG A O    1 
ATOM   5079 C  CB   . ARG A 1 341 ? 132.342 187.518 157.692 1.00 112.06 ? 352 ARG A CB   1 
ATOM   5080 C  CG   . ARG A 1 341 ? 133.808 187.779 157.386 1.00 112.56 ? 352 ARG A CG   1 
ATOM   5081 C  CD   . ARG A 1 341 ? 134.701 186.666 157.910 1.00 111.90 ? 352 ARG A CD   1 
ATOM   5082 N  NE   . ARG A 1 341 ? 135.910 186.514 157.110 1.00 111.25 ? 352 ARG A NE   1 
ATOM   5083 C  CZ   . ARG A 1 341 ? 136.987 187.281 157.219 1.00 111.86 ? 352 ARG A CZ   1 
ATOM   5084 N  NH1  . ARG A 1 341 ? 137.043 188.276 158.090 1.00 113.32 ? 352 ARG A NH1  1 
ATOM   5085 N  NH2  . ARG A 1 341 ? 138.034 187.045 156.434 1.00 110.73 ? 352 ARG A NH2  1 
ATOM   5086 H  H    . ARG A 1 341 ? 131.261 188.455 155.724 1.00 108.03 ? 352 ARG A H    1 
ATOM   5087 H  HA   . ARG A 1 341 ? 132.248 186.097 156.219 1.00 109.38 ? 352 ARG A HA   1 
ATOM   5088 H  HB2  . ARG A 1 341 ? 131.904 188.377 157.796 1.00 109.30 ? 352 ARG A HB2  1 
ATOM   5089 H  HB3  . ARG A 1 341 ? 132.297 187.024 158.526 1.00 109.96 ? 352 ARG A HB3  1 
ATOM   5090 H  HG2  . ARG A 1 341 ? 133.928 187.834 156.425 1.00 109.22 ? 352 ARG A HG2  1 
ATOM   5091 H  HG3  . ARG A 1 341 ? 134.080 188.610 157.806 1.00 109.34 ? 352 ARG A HG3  1 
ATOM   5092 H  HD2  . ARG A 1 341 ? 134.962 186.869 158.822 1.00 109.82 ? 352 ARG A HD2  1 
ATOM   5093 H  HD3  . ARG A 1 341 ? 134.213 185.828 157.882 1.00 109.94 ? 352 ARG A HD3  1 
ATOM   5094 H  HE   . ARG A 1 341 ? 135.905 185.919 156.489 1.00 109.22 ? 352 ARG A HE   1 
ATOM   5095 H  HH11 . ARG A 1 341 ? 136.373 188.440 158.604 1.00 109.76 ? 352 ARG A HH11 1 
ATOM   5096 H  HH12 . ARG A 1 341 ? 137.751 188.760 158.143 1.00 109.86 ? 352 ARG A HH12 1 
ATOM   5097 H  HH21 . ARG A 1 341 ? 138.008 186.401 155.865 1.00 109.22 ? 352 ARG A HH21 1 
ATOM   5098 H  HH22 . ARG A 1 341 ? 138.737 187.536 156.496 1.00 109.24 ? 352 ARG A HH22 1 
ATOM   5099 N  N    . ASP A 1 342 ? 129.337 186.572 157.454 1.00 108.69 ? 353 ASP A N    1 
ATOM   5100 C  CA   . ASP A 1 342 ? 128.139 185.885 157.903 1.00 108.33 ? 353 ASP A CA   1 
ATOM   5101 C  C    . ASP A 1 342 ? 127.391 185.293 156.709 1.00 105.56 ? 353 ASP A C    1 
ATOM   5102 O  O    . ASP A 1 342 ? 127.753 185.496 155.547 1.00 103.76 ? 353 ASP A O    1 
ATOM   5103 C  CB   . ASP A 1 342 ? 127.235 186.842 158.678 1.00 106.65 ? 353 ASP A CB   1 
ATOM   5104 C  CG   . ASP A 1 342 ? 126.499 187.811 157.773 1.00 103.38 ? 353 ASP A CG   1 
ATOM   5105 O  OD1  . ASP A 1 342 ? 127.119 188.326 156.820 1.00 106.99 ? 353 ASP A OD1  1 
ATOM   5106 O  OD2  . ASP A 1 342 ? 125.299 188.059 158.015 1.00 99.54  ? 353 ASP A OD2  1 
ATOM   5107 H  H    . ASP A 1 342 ? 129.240 187.422 157.367 1.00 106.08 ? 353 ASP A H    1 
ATOM   5108 H  HA   . ASP A 1 342 ? 128.389 185.159 158.495 1.00 106.00 ? 353 ASP A HA   1 
ATOM   5109 H  HB2  . ASP A 1 342 ? 126.574 186.327 159.167 1.00 105.97 ? 353 ASP A HB2  1 
ATOM   5110 H  HB3  . ASP A 1 342 ? 127.777 187.359 159.295 1.00 105.85 ? 353 ASP A HB3  1 
ATOM   5111 N  N    . GLY A 1 343 ? 126.326 184.549 157.011 1.00 105.05 ? 354 GLY A N    1 
ATOM   5112 C  CA   . GLY A 1 343 ? 125.535 183.930 155.963 1.00 105.50 ? 354 GLY A CA   1 
ATOM   5113 C  C    . GLY A 1 343 ? 124.766 184.913 155.106 1.00 108.82 ? 354 GLY A C    1 
ATOM   5114 O  O    . GLY A 1 343 ? 124.361 184.563 153.992 1.00 107.32 ? 354 GLY A O    1 
ATOM   5115 H  H    . GLY A 1 343 ? 126.047 184.392 157.809 1.00 106.65 ? 354 GLY A H    1 
ATOM   5116 H  HA2  . GLY A 1 343 ? 126.121 183.419 155.383 1.00 106.14 ? 354 GLY A HA2  1 
ATOM   5117 H  HA3  . GLY A 1 343 ? 124.898 183.318 156.365 1.00 106.57 ? 354 GLY A HA3  1 
ATOM   5118 N  N    . LYS A 1 344 ? 124.553 186.130 155.597 1.00 111.42 ? 355 LYS A N    1 
ATOM   5119 C  CA   . LYS A 1 344 ? 123.794 187.110 154.836 1.00 109.82 ? 355 LYS A CA   1 
ATOM   5120 C  C    . LYS A 1 344 ? 124.528 187.430 153.534 1.00 106.47 ? 355 LYS A C    1 
ATOM   5121 O  O    . LYS A 1 344 ? 125.758 187.552 153.530 1.00 104.29 ? 355 LYS A O    1 
ATOM   5122 C  CB   . LYS A 1 344 ? 123.599 188.385 155.659 1.00 105.64 ? 355 LYS A CB   1 
ATOM   5123 C  CG   . LYS A 1 344 ? 122.711 189.437 155.007 1.00 104.78 ? 355 LYS A CG   1 
ATOM   5124 C  CD   . LYS A 1 344 ? 121.241 189.062 155.119 1.00 108.19 ? 355 LYS A CD   1 
ATOM   5125 C  CE   . LYS A 1 344 ? 120.339 190.124 154.509 1.00 107.42 ? 355 LYS A CE   1 
ATOM   5126 N  NZ   . LYS A 1 344 ? 119.923 189.782 153.121 1.00 108.38 ? 355 LYS A NZ   1 
ATOM   5127 H  H    . LYS A 1 344 ? 124.833 186.409 156.360 1.00 107.52 ? 355 LYS A H    1 
ATOM   5128 H  HA   . LYS A 1 344 ? 122.922 186.741 154.638 1.00 108.00 ? 355 LYS A HA   1 
ATOM   5129 H  HB2  . LYS A 1 344 ? 123.195 188.146 156.508 1.00 107.26 ? 355 LYS A HB2  1 
ATOM   5130 H  HB3  . LYS A 1 344 ? 124.467 188.786 155.813 1.00 107.09 ? 355 LYS A HB3  1 
ATOM   5131 H  HG2  . LYS A 1 344 ? 122.838 190.287 155.458 1.00 106.90 ? 355 LYS A HG2  1 
ATOM   5132 H  HG3  . LYS A 1 344 ? 122.936 189.519 154.068 1.00 107.42 ? 355 LYS A HG3  1 
ATOM   5133 H  HD2  . LYS A 1 344 ? 121.087 188.227 154.649 1.00 108.09 ? 355 LYS A HD2  1 
ATOM   5134 H  HD3  . LYS A 1 344 ? 121.006 188.966 156.055 1.00 107.28 ? 355 LYS A HD3  1 
ATOM   5135 H  HE2  . LYS A 1 344 ? 119.539 190.210 155.051 1.00 107.59 ? 355 LYS A HE2  1 
ATOM   5136 H  HE3  . LYS A 1 344 ? 120.815 190.969 154.482 1.00 107.40 ? 355 LYS A HE3  1 
ATOM   5137 H  HZ1  . LYS A 1 344 ? 120.621 189.839 152.572 1.00 107.87 ? 355 LYS A HZ1  1 
ATOM   5138 H  HZ2  . LYS A 1 344 ? 119.600 188.953 153.095 1.00 107.73 ? 355 LYS A HZ2  1 
ATOM   5139 H  HZ3  . LYS A 1 344 ? 119.293 190.347 152.845 1.00 107.62 ? 355 LYS A HZ3  1 
ATOM   5140 N  N    . PRO A 1 345 ? 123.816 187.565 152.413 1.00 101.04 ? 356 PRO A N    1 
ATOM   5141 C  CA   . PRO A 1 345 ? 124.498 187.895 151.155 1.00 98.41  ? 356 PRO A CA   1 
ATOM   5142 C  C    . PRO A 1 345 ? 125.249 189.214 151.258 1.00 97.86  ? 356 PRO A C    1 
ATOM   5143 O  O    . PRO A 1 345 ? 124.794 190.163 151.900 1.00 99.10  ? 356 PRO A O    1 
ATOM   5144 C  CB   . PRO A 1 345 ? 123.353 187.974 150.138 1.00 102.11 ? 356 PRO A CB   1 
ATOM   5145 C  CG   . PRO A 1 345 ? 122.254 187.173 150.735 1.00 102.79 ? 356 PRO A CG   1 
ATOM   5146 C  CD   . PRO A 1 345 ? 122.370 187.368 152.213 1.00 103.79 ? 356 PRO A CD   1 
ATOM   5147 H  HA   . PRO A 1 345 ? 125.111 187.188 150.902 1.00 100.39 ? 356 PRO A HA   1 
ATOM   5148 H  HB2  . PRO A 1 345 ? 123.081 188.898 150.022 1.00 101.15 ? 356 PRO A HB2  1 
ATOM   5149 H  HB3  . PRO A 1 345 ? 123.638 187.591 149.294 1.00 101.43 ? 356 PRO A HB3  1 
ATOM   5150 H  HG2  . PRO A 1 345 ? 121.400 187.502 150.414 1.00 101.38 ? 356 PRO A HG2  1 
ATOM   5151 H  HG3  . PRO A 1 345 ? 122.369 186.238 150.504 1.00 101.05 ? 356 PRO A HG3  1 
ATOM   5152 H  HD2  . PRO A 1 345 ? 121.878 188.155 152.491 1.00 102.05 ? 356 PRO A HD2  1 
ATOM   5153 H  HD3  . PRO A 1 345 ? 122.064 186.573 152.676 1.00 101.56 ? 356 PRO A HD3  1 
ATOM   5154 N  N    . SER A 1 346 ? 126.412 189.264 150.612 1.00 94.48  ? 357 SER A N    1 
ATOM   5155 C  CA   . SER A 1 346 ? 127.254 190.449 150.598 1.00 98.19  ? 357 SER A CA   1 
ATOM   5156 C  C    . SER A 1 346 ? 127.740 190.706 149.180 1.00 91.45  ? 357 SER A C    1 
ATOM   5157 O  O    . SER A 1 346 ? 127.828 189.789 148.361 1.00 92.51  ? 357 SER A O    1 
ATOM   5158 C  CB   . SER A 1 346 ? 128.454 190.299 151.544 1.00 103.26 ? 357 SER A CB   1 
ATOM   5159 O  OG   . SER A 1 346 ? 129.487 189.536 150.946 1.00 103.94 ? 357 SER A OG   1 
ATOM   5160 H  H    . SER A 1 346 ? 126.739 188.606 150.165 1.00 96.61  ? 357 SER A H    1 
ATOM   5161 H  HA   . SER A 1 346 ? 126.737 191.216 150.887 1.00 97.46  ? 357 SER A HA   1 
ATOM   5162 H  HB2  . SER A 1 346 ? 128.797 191.180 151.758 1.00 97.91  ? 357 SER A HB2  1 
ATOM   5163 H  HB3  . SER A 1 346 ? 128.159 189.854 152.353 1.00 98.46  ? 357 SER A HB3  1 
ATOM   5164 H  HG   . SER A 1 346 ? 129.876 189.988 150.354 1.00 97.23  ? 357 SER A HG   1 
ATOM   5165 N  N    . TRP A 1 347 ? 128.055 191.967 148.902 1.00 85.31  ? 358 TRP A N    1 
ATOM   5166 C  CA   . TRP A 1 347 ? 128.449 192.411 147.573 1.00 87.23  ? 358 TRP A CA   1 
ATOM   5167 C  C    . TRP A 1 347 ? 129.868 192.957 147.618 1.00 89.07  ? 358 TRP A C    1 
ATOM   5168 O  O    . TRP A 1 347 ? 130.211 193.733 148.515 1.00 94.67  ? 358 TRP A O    1 
ATOM   5169 C  CB   . TRP A 1 347 ? 127.484 193.477 147.045 1.00 92.04  ? 358 TRP A CB   1 
ATOM   5170 C  CG   . TRP A 1 347 ? 126.113 192.948 146.741 1.00 94.78  ? 358 TRP A CG   1 
ATOM   5171 C  CD1  . TRP A 1 347 ? 125.570 192.750 145.505 1.00 95.84  ? 358 TRP A CD1  1 
ATOM   5172 C  CD2  . TRP A 1 347 ? 125.115 192.544 147.687 1.00 90.45  ? 358 TRP A CD2  1 
ATOM   5173 N  NE1  . TRP A 1 347 ? 124.297 192.249 145.622 1.00 94.27  ? 358 TRP A NE1  1 
ATOM   5174 C  CE2  . TRP A 1 347 ? 123.993 192.114 146.951 1.00 94.36  ? 358 TRP A CE2  1 
ATOM   5175 C  CE3  . TRP A 1 347 ? 125.059 192.507 149.083 1.00 84.55  ? 358 TRP A CE3  1 
ATOM   5176 C  CZ2  . TRP A 1 347 ? 122.831 191.652 147.564 1.00 93.46  ? 358 TRP A CZ2  1 
ATOM   5177 C  CZ3  . TRP A 1 347 ? 123.905 192.047 149.689 1.00 88.02  ? 358 TRP A CZ3  1 
ATOM   5178 C  CH2  . TRP A 1 347 ? 122.807 191.626 148.931 1.00 93.20  ? 358 TRP A CH2  1 
ATOM   5179 H  H    . TRP A 1 347 ? 128.048 192.600 149.484 1.00 91.71  ? 358 TRP A H    1 
ATOM   5180 H  HA   . TRP A 1 347 ? 128.437 191.657 146.966 1.00 90.87  ? 358 TRP A HA   1 
ATOM   5181 H  HB2  . TRP A 1 347 ? 127.393 194.176 147.711 1.00 91.58  ? 358 TRP A HB2  1 
ATOM   5182 H  HB3  . TRP A 1 347 ? 127.846 193.846 146.225 1.00 91.52  ? 358 TRP A HB3  1 
ATOM   5183 H  HD1  . TRP A 1 347 ? 126.001 192.927 144.700 1.00 91.45  ? 358 TRP A HD1  1 
ATOM   5184 H  HE1  . TRP A 1 347 ? 123.775 192.053 144.967 1.00 91.08  ? 358 TRP A HE1  1 
ATOM   5185 H  HE3  . TRP A 1 347 ? 125.785 192.784 149.594 1.00 90.78  ? 358 TRP A HE3  1 
ATOM   5186 H  HZ2  . TRP A 1 347 ? 122.099 191.372 147.063 1.00 91.64  ? 358 TRP A HZ2  1 
ATOM   5187 H  HZ3  . TRP A 1 347 ? 123.857 192.017 150.617 1.00 91.65  ? 358 TRP A HZ3  1 
ATOM   5188 H  HH2  . TRP A 1 347 ? 122.044 191.322 149.366 1.00 92.60  ? 358 TRP A HH2  1 
ATOM   5189 N  N    . CYS A 1 348 ? 130.685 192.550 146.651 1.00 75.21  ? 359 CYS A N    1 
ATOM   5190 C  CA   . CYS A 1 348 ? 132.063 193.005 146.528 1.00 75.36  ? 359 CYS A CA   1 
ATOM   5191 C  C    . CYS A 1 348 ? 132.223 193.728 145.201 1.00 69.94  ? 359 CYS A C    1 
ATOM   5192 O  O    . CYS A 1 348 ? 131.826 193.204 144.155 1.00 74.72  ? 359 CYS A O    1 
ATOM   5193 C  CB   . CYS A 1 348 ? 133.037 191.831 146.610 1.00 78.63  ? 359 CYS A CB   1 
ATOM   5194 S  SG   . CYS A 1 348 ? 133.052 191.006 148.212 1.00 86.63  ? 359 CYS A SG   1 
ATOM   5195 H  H    . CYS A 1 348 ? 130.455 191.994 146.036 1.00 78.88  ? 359 CYS A H    1 
ATOM   5196 H  HA   . CYS A 1 348 ? 132.268 193.626 147.244 1.00 79.10  ? 359 CYS A HA   1 
ATOM   5197 H  HB2  . CYS A 1 348 ? 132.787 191.175 145.942 1.00 77.66  ? 359 CYS A HB2  1 
ATOM   5198 H  HB3  . CYS A 1 348 ? 133.934 192.156 146.434 1.00 78.50  ? 359 CYS A HB3  1 
ATOM   5199 H  HG   . CYS A 1 348 ? 133.780 190.053 148.167 1.00 78.34  ? 359 CYS A HG   1 
ATOM   5200 N  N    . ARG A 1 349 ? 132.809 194.922 145.242 1.00 72.73  ? 360 ARG A N    1 
ATOM   5201 C  CA   . ARG A 1 349 ? 132.969 195.744 144.055 1.00 77.78  ? 360 ARG A CA   1 
ATOM   5202 C  C    . ARG A 1 349 ? 134.426 196.147 143.884 1.00 79.24  ? 360 ARG A C    1 
ATOM   5203 O  O    . ARG A 1 349 ? 135.151 196.361 144.860 1.00 85.01  ? 360 ARG A O    1 
ATOM   5204 C  CB   . ARG A 1 349 ? 132.094 197.000 144.121 1.00 82.04  ? 360 ARG A CB   1 
ATOM   5205 C  CG   . ARG A 1 349 ? 131.892 197.673 142.774 1.00 82.27  ? 360 ARG A CG   1 
ATOM   5206 C  CD   . ARG A 1 349 ? 130.566 198.412 142.708 1.00 80.15  ? 360 ARG A CD   1 
ATOM   5207 N  NE   . ARG A 1 349 ? 129.425 197.505 142.719 1.00 82.95  ? 360 ARG A NE   1 
ATOM   5208 C  CZ   . ARG A 1 349 ? 128.182 197.862 142.427 1.00 84.51  ? 360 ARG A CZ   1 
ATOM   5209 N  NH1  . ARG A 1 349 ? 127.879 199.107 142.098 1.00 85.37  ? 360 ARG A NH1  1 
ATOM   5210 N  NH2  . ARG A 1 349 ? 127.218 196.947 142.469 1.00 83.75  ? 360 ARG A NH2  1 
ATOM   5211 H  H    . ARG A 1 349 ? 133.124 195.280 145.958 1.00 81.18  ? 360 ARG A H    1 
ATOM   5212 H  HA   . ARG A 1 349 ? 132.703 195.234 143.278 1.00 81.62  ? 360 ARG A HA   1 
ATOM   5213 H  HB2  . ARG A 1 349 ? 131.221 196.754 144.464 1.00 82.24  ? 360 ARG A HB2  1 
ATOM   5214 H  HB3  . ARG A 1 349 ? 132.512 197.643 144.715 1.00 81.86  ? 360 ARG A HB3  1 
ATOM   5215 H  HG2  . ARG A 1 349 ? 132.608 198.310 142.628 1.00 81.82  ? 360 ARG A HG2  1 
ATOM   5216 H  HG3  . ARG A 1 349 ? 131.897 196.999 142.077 1.00 82.03  ? 360 ARG A HG3  1 
ATOM   5217 H  HD2  . ARG A 1 349 ? 130.492 199.002 143.474 1.00 82.00  ? 360 ARG A HD2  1 
ATOM   5218 H  HD3  . ARG A 1 349 ? 130.532 198.926 141.886 1.00 81.82  ? 360 ARG A HD3  1 
ATOM   5219 H  HE   . ARG A 1 349 ? 129.569 196.683 142.926 1.00 82.65  ? 360 ARG A HE   1 
ATOM   5220 H  HH11 . ARG A 1 349 ? 128.493 199.709 142.068 1.00 82.87  ? 360 ARG A HH11 1 
ATOM   5221 H  HH12 . ARG A 1 349 ? 127.065 199.316 141.914 1.00 82.92  ? 360 ARG A HH12 1 
ATOM   5222 H  HH21 . ARG A 1 349 ? 127.404 196.135 142.682 1.00 82.44  ? 360 ARG A HH21 1 
ATOM   5223 H  HH22 . ARG A 1 349 ? 126.408 197.168 142.282 1.00 82.28  ? 360 ARG A HH22 1 
ATOM   5224 N  N    . LEU A 1 350 ? 134.844 196.242 142.624 1.00 75.85  ? 361 LEU A N    1 
ATOM   5225 C  CA   . LEU A 1 350 ? 136.166 196.726 142.251 1.00 70.58  ? 361 LEU A CA   1 
ATOM   5226 C  C    . LEU A 1 350 ? 135.990 197.822 141.213 1.00 77.38  ? 361 LEU A C    1 
ATOM   5227 O  O    . LEU A 1 350 ? 135.296 197.623 140.211 1.00 91.55  ? 361 LEU A O    1 
ATOM   5228 C  CB   . LEU A 1 350 ? 137.037 195.595 141.690 1.00 76.36  ? 361 LEU A CB   1 
ATOM   5229 C  CG   . LEU A 1 350 ? 138.544 195.847 141.578 1.00 83.56  ? 361 LEU A CG   1 
ATOM   5230 C  CD1  . LEU A 1 350 ? 139.275 194.543 141.292 1.00 86.76  ? 361 LEU A CD1  1 
ATOM   5231 C  CD2  . LEU A 1 350 ? 138.867 196.875 140.504 1.00 83.19  ? 361 LEU A CD2  1 
ATOM   5232 H  H    . LEU A 1 350 ? 134.362 196.023 141.946 1.00 80.93  ? 361 LEU A H    1 
ATOM   5233 H  HA   . LEU A 1 350 ? 136.610 197.101 143.027 1.00 79.12  ? 361 LEU A HA   1 
ATOM   5234 H  HB2  . LEU A 1 350 ? 136.920 194.817 142.257 1.00 80.21  ? 361 LEU A HB2  1 
ATOM   5235 H  HB3  . LEU A 1 350 ? 136.718 195.388 140.798 1.00 80.44  ? 361 LEU A HB3  1 
ATOM   5236 H  HG   . LEU A 1 350 ? 138.868 196.189 142.425 1.00 80.79  ? 361 LEU A HG   1 
ATOM   5237 H  HD11 . LEU A 1 350 ? 139.057 193.899 141.982 1.00 81.60  ? 361 LEU A HD11 1 
ATOM   5238 H  HD12 . LEU A 1 350 ? 140.230 194.712 141.286 1.00 81.77  ? 361 LEU A HD12 1 
ATOM   5239 H  HD13 . LEU A 1 350 ? 138.993 194.208 140.427 1.00 81.86  ? 361 LEU A HD13 1 
ATOM   5240 H  HD21 . LEU A 1 350 ? 139.782 196.745 140.209 1.00 80.99  ? 361 LEU A HD21 1 
ATOM   5241 H  HD22 . LEU A 1 350 ? 138.259 196.755 139.758 1.00 81.14  ? 361 LEU A HD22 1 
ATOM   5242 H  HD23 . LEU A 1 350 ? 138.763 197.764 140.877 1.00 80.45  ? 361 LEU A HD23 1 
ATOM   5243 N  N    . TYR A 1 351 ? 136.609 198.973 141.453 1.00 74.34  ? 362 TYR A N    1 
ATOM   5244 C  CA   . TYR A 1 351 ? 136.518 200.118 140.547 1.00 82.60  ? 362 TYR A CA   1 
ATOM   5245 C  C    . TYR A 1 351 ? 137.792 200.191 139.713 1.00 88.86  ? 362 TYR A C    1 
ATOM   5246 O  O    . TYR A 1 351 ? 138.806 200.749 140.133 1.00 90.35  ? 362 TYR A O    1 
ATOM   5247 C  CB   . TYR A 1 351 ? 136.272 201.403 141.329 1.00 85.82  ? 362 TYR A CB   1 
ATOM   5248 C  CG   . TYR A 1 351 ? 134.902 201.465 141.973 1.00 84.27  ? 362 TYR A CG   1 
ATOM   5249 C  CD1  . TYR A 1 351 ? 133.801 200.876 141.366 1.00 83.19  ? 362 TYR A CD1  1 
ATOM   5250 C  CD2  . TYR A 1 351 ? 134.709 202.111 143.183 1.00 86.68  ? 362 TYR A CD2  1 
ATOM   5251 C  CE1  . TYR A 1 351 ? 132.552 200.932 141.941 1.00 82.00  ? 362 TYR A CE1  1 
ATOM   5252 C  CE2  . TYR A 1 351 ? 133.460 202.169 143.768 1.00 84.83  ? 362 TYR A CE2  1 
ATOM   5253 C  CZ   . TYR A 1 351 ? 132.386 201.575 143.143 1.00 84.67  ? 362 TYR A CZ   1 
ATOM   5254 O  OH   . TYR A 1 351 ? 131.137 201.627 143.717 1.00 90.92  ? 362 TYR A OH   1 
ATOM   5255 H  H    . TYR A 1 351 ? 137.094 199.119 142.148 1.00 82.97  ? 362 TYR A H    1 
ATOM   5256 H  HA   . TYR A 1 351 ? 135.784 199.981 139.932 1.00 84.81  ? 362 TYR A HA   1 
ATOM   5257 H  HB2  . TYR A 1 351 ? 136.935 201.465 142.035 1.00 85.09  ? 362 TYR A HB2  1 
ATOM   5258 H  HB3  . TYR A 1 351 ? 136.360 202.159 140.728 1.00 85.27  ? 362 TYR A HB3  1 
ATOM   5259 H  HD1  . TYR A 1 351 ? 133.906 200.439 140.552 1.00 85.12  ? 362 TYR A HD1  1 
ATOM   5260 H  HD2  . TYR A 1 351 ? 135.433 202.511 143.608 1.00 85.41  ? 362 TYR A HD2  1 
ATOM   5261 H  HE1  . TYR A 1 351 ? 131.826 200.531 141.520 1.00 84.78  ? 362 TYR A HE1  1 
ATOM   5262 H  HE2  . TYR A 1 351 ? 133.345 202.606 144.580 1.00 84.99  ? 362 TYR A HE2  1 
ATOM   5263 H  HH   . TYR A 1 351 ? 131.209 201.734 144.546 1.00 86.01  ? 362 TYR A HH   1 
ATOM   5264 N  N    . TYR A 1 352 ? 137.725 199.620 138.514 1.00 98.36  ? 363 TYR A N    1 
ATOM   5265 C  CA   . TYR A 1 352 ? 138.858 199.645 137.604 1.00 93.65  ? 363 TYR A CA   1 
ATOM   5266 C  C    . TYR A 1 352 ? 139.121 201.050 137.078 1.00 94.72  ? 363 TYR A C    1 
ATOM   5267 O  O    . TYR A 1 352 ? 138.236 201.910 137.052 1.00 94.95  ? 363 TYR A O    1 
ATOM   5268 C  CB   . TYR A 1 352 ? 138.619 198.736 136.405 1.00 87.55  ? 363 TYR A CB   1 
ATOM   5269 C  CG   . TYR A 1 352 ? 139.857 198.538 135.571 1.00 91.12  ? 363 TYR A CG   1 
ATOM   5270 C  CD1  . TYR A 1 352 ? 141.057 198.155 136.149 1.00 90.51  ? 363 TYR A CD1  1 
ATOM   5271 C  CD2  . TYR A 1 352 ? 139.849 198.833 134.216 1.00 96.83  ? 363 TYR A CD2  1 
ATOM   5272 C  CE1  . TYR A 1 352 ? 142.190 197.991 135.388 1.00 94.54  ? 363 TYR A CE1  1 
ATOM   5273 C  CE2  . TYR A 1 352 ? 140.986 198.695 133.448 1.00 98.76  ? 363 TYR A CE2  1 
ATOM   5274 C  CZ   . TYR A 1 352 ? 142.156 198.270 134.038 1.00 97.22  ? 363 TYR A CZ   1 
ATOM   5275 O  OH   . TYR A 1 352 ? 143.298 198.122 133.280 1.00 93.71  ? 363 TYR A OH   1 
ATOM   5276 H  H    . TYR A 1 352 ? 137.033 199.215 138.203 1.00 92.94  ? 363 TYR A H    1 
ATOM   5277 H  HA   . TYR A 1 352 ? 139.643 199.330 138.076 1.00 92.84  ? 363 TYR A HA   1 
ATOM   5278 H  HB2  . TYR A 1 352 ? 138.305 197.872 136.715 1.00 92.21  ? 363 TYR A HB2  1 
ATOM   5279 H  HB3  . TYR A 1 352 ? 137.959 199.154 135.834 1.00 92.15  ? 363 TYR A HB3  1 
ATOM   5280 H  HD1  . TYR A 1 352 ? 141.084 197.955 137.058 1.00 92.24  ? 363 TYR A HD1  1 
ATOM   5281 H  HD2  . TYR A 1 352 ? 139.058 199.112 133.814 1.00 93.69  ? 363 TYR A HD2  1 
ATOM   5282 H  HE1  . TYR A 1 352 ? 142.984 197.717 135.786 1.00 93.32  ? 363 TYR A HE1  1 
ATOM   5283 H  HE2  . TYR A 1 352 ? 140.958 198.872 132.536 1.00 93.75  ? 363 TYR A HE2  1 
ATOM   5284 H  HH   . TYR A 1 352 ? 143.104 198.099 132.463 1.00 93.51  ? 363 TYR A HH   1 
ATOM   5285 N  N    . SER A 1 353 ? 140.363 201.273 136.661 1.00 96.53  ? 364 SER A N    1 
ATOM   5286 C  CA   . SER A 1 353 ? 140.705 202.409 135.821 1.00 95.30  ? 364 SER A CA   1 
ATOM   5287 C  C    . SER A 1 353 ? 141.970 202.066 135.049 1.00 95.89  ? 364 SER A C    1 
ATOM   5288 O  O    . SER A 1 353 ? 142.895 201.465 135.601 1.00 96.87  ? 364 SER A O    1 
ATOM   5289 C  CB   . SER A 1 353 ? 140.899 203.683 136.648 1.00 99.65  ? 364 SER A CB   1 
ATOM   5290 O  OG   . SER A 1 353 ? 139.650 204.257 136.983 1.00 97.94  ? 364 SER A OG   1 
ATOM   5291 H  H    . SER A 1 353 ? 141.033 200.773 136.861 1.00 96.70  ? 364 SER A H    1 
ATOM   5292 H  HA   . SER A 1 353 ? 139.990 202.562 135.183 1.00 96.36  ? 364 SER A HA   1 
ATOM   5293 H  HB2  . SER A 1 353 ? 141.361 203.460 137.469 1.00 97.65  ? 364 SER A HB2  1 
ATOM   5294 H  HB3  . SER A 1 353 ? 141.417 204.323 136.136 1.00 97.60  ? 364 SER A HB3  1 
ATOM   5295 H  HG   . SER A 1 353 ? 139.767 204.928 137.471 1.00 97.54  ? 364 SER A HG   1 
ATOM   5296 N  N    . ARG A 1 354 ? 141.997 202.436 133.767 1.00 101.24 ? 365 ARG A N    1 
ATOM   5297 C  CA   . ARG A 1 354 ? 143.200 202.220 132.972 1.00 102.79 ? 365 ARG A CA   1 
ATOM   5298 C  C    . ARG A 1 354 ? 144.376 202.996 133.550 1.00 106.13 ? 365 ARG A C    1 
ATOM   5299 O  O    . ARG A 1 354 ? 145.490 202.469 133.646 1.00 107.26 ? 365 ARG A O    1 
ATOM   5300 C  CB   . ARG A 1 354 ? 142.951 202.625 131.519 1.00 100.24 ? 365 ARG A CB   1 
ATOM   5301 H  H    . ARG A 1 354 ? 141.345 202.803 133.343 1.00 102.57 ? 365 ARG A H    1 
ATOM   5302 H  HA   . ARG A 1 354 ? 143.426 201.277 132.987 1.00 102.85 ? 365 ARG A HA   1 
ATOM   5303 N  N    . ASN A 1 355 ? 144.147 204.251 133.941 1.00 107.56 ? 366 ASN A N    1 
ATOM   5304 C  CA   . ASN A 1 355 ? 145.195 205.021 134.602 1.00 107.84 ? 366 ASN A CA   1 
ATOM   5305 C  C    . ASN A 1 355 ? 145.576 204.393 135.937 1.00 103.95 ? 366 ASN A C    1 
ATOM   5306 O  O    . ASN A 1 355 ? 146.764 204.298 136.272 1.00 101.69 ? 366 ASN A O    1 
ATOM   5307 C  CB   . ASN A 1 355 ? 144.730 206.462 134.800 1.00 107.91 ? 366 ASN A CB   1 
ATOM   5308 C  CG   . ASN A 1 355 ? 144.285 207.112 133.506 1.00 107.61 ? 366 ASN A CG   1 
ATOM   5309 O  OD1  . ASN A 1 355 ? 145.103 207.430 132.643 1.00 107.41 ? 366 ASN A OD1  1 
ATOM   5310 N  ND2  . ASN A 1 355 ? 142.979 207.300 133.357 1.00 106.40 ? 366 ASN A ND2  1 
ATOM   5311 H  H    . ASN A 1 355 ? 143.403 204.671 133.835 1.00 105.54 ? 366 ASN A H    1 
ATOM   5312 H  HA   . ASN A 1 355 ? 145.983 205.033 134.037 1.00 106.36 ? 366 ASN A HA   1 
ATOM   5313 H  HB2  . ASN A 1 355 ? 143.979 206.471 135.414 1.00 105.90 ? 366 ASN A HB2  1 
ATOM   5314 H  HB3  . ASN A 1 355 ? 145.463 206.984 135.163 1.00 106.11 ? 366 ASN A HB3  1 
ATOM   5315 H  HD21 . ASN A 1 355 ? 142.675 207.663 132.639 1.00 105.86 ? 366 ASN A HD21 1 
ATOM   5316 H  HD22 . ASN A 1 355 ? 142.436 207.061 133.980 1.00 105.85 ? 366 ASN A HD22 1 
ATOM   5317 N  N    . ASP A 1 356 ? 144.581 203.959 136.714 1.00 95.49  ? 367 ASP A N    1 
ATOM   5318 C  CA   . ASP A 1 356 ? 144.875 203.280 137.970 1.00 94.94  ? 367 ASP A CA   1 
ATOM   5319 C  C    . ASP A 1 356 ? 145.631 201.983 137.722 1.00 93.85  ? 367 ASP A C    1 
ATOM   5320 O  O    . ASP A 1 356 ? 146.529 201.624 138.491 1.00 95.32  ? 367 ASP A O    1 
ATOM   5321 C  CB   . ASP A 1 356 ? 143.583 203.007 138.739 1.00 95.63  ? 367 ASP A CB   1 
ATOM   5322 H  H    . ASP A 1 356 ? 143.744 204.045 136.538 1.00 96.16  ? 367 ASP A H    1 
ATOM   5323 H  HA   . ASP A 1 356 ? 145.434 203.853 138.517 1.00 95.43  ? 367 ASP A HA   1 
ATOM   5324 N  N    . ARG A 1 357 ? 145.275 201.257 136.661 1.00 89.25  ? 368 ARG A N    1 
ATOM   5325 C  CA   . ARG A 1 357 ? 146.006 200.036 136.344 1.00 90.60  ? 368 ARG A CA   1 
ATOM   5326 C  C    . ARG A 1 357 ? 147.447 200.347 135.979 1.00 93.11  ? 368 ARG A C    1 
ATOM   5327 O  O    . ARG A 1 357 ? 148.360 199.613 136.363 1.00 92.46  ? 368 ARG A O    1 
ATOM   5328 C  CB   . ARG A 1 357 ? 145.323 199.282 135.207 1.00 89.29  ? 368 ARG A CB   1 
ATOM   5329 C  CG   . ARG A 1 357 ? 145.889 197.877 134.972 1.00 88.01  ? 368 ARG A CG   1 
ATOM   5330 C  CD   . ARG A 1 357 ? 147.060 197.859 133.998 1.00 90.40  ? 368 ARG A CD   1 
ATOM   5331 N  NE   . ARG A 1 357 ? 146.698 198.432 132.709 1.00 91.88  ? 368 ARG A NE   1 
ATOM   5332 C  CZ   . ARG A 1 357 ? 146.069 197.774 131.744 1.00 90.02  ? 368 ARG A CZ   1 
ATOM   5333 N  NH1  . ARG A 1 357 ? 145.726 196.503 131.880 1.00 87.83  ? 368 ARG A NH1  1 
ATOM   5334 N  NH2  . ARG A 1 357 ? 145.775 198.408 130.613 1.00 90.60  ? 368 ARG A NH2  1 
ATOM   5335 H  H    . ARG A 1 357 ? 144.632 201.447 136.122 1.00 91.55  ? 368 ARG A H    1 
ATOM   5336 H  HA   . ARG A 1 357 ? 146.011 199.461 137.125 1.00 90.81  ? 368 ARG A HA   1 
ATOM   5337 H  HB2  . ARG A 1 357 ? 144.387 199.209 135.418 1.00 90.95  ? 368 ARG A HB2  1 
ATOM   5338 H  HB3  . ARG A 1 357 ? 145.436 199.792 134.391 1.00 91.16  ? 368 ARG A HB3  1 
ATOM   5339 H  HG2  . ARG A 1 357 ? 146.215 197.531 135.817 1.00 90.55  ? 368 ARG A HG2  1 
ATOM   5340 H  HG3  . ARG A 1 357 ? 145.191 197.300 134.625 1.00 90.05  ? 368 ARG A HG3  1 
ATOM   5341 H  HD2  . ARG A 1 357 ? 147.795 198.374 134.360 1.00 90.85  ? 368 ARG A HD2  1 
ATOM   5342 H  HD3  . ARG A 1 357 ? 147.345 196.943 133.856 1.00 90.56  ? 368 ARG A HD3  1 
ATOM   5343 H  HE   . ARG A 1 357 ? 146.843 199.272 132.591 1.00 91.16  ? 368 ARG A HE   1 
ATOM   5344 H  HH11 . ARG A 1 357 ? 145.908 196.077 132.604 1.00 90.37  ? 368 ARG A HH11 1 
ATOM   5345 H  HH12 . ARG A 1 357 ? 145.319 196.102 131.237 1.00 90.31  ? 368 ARG A HH12 1 
ATOM   5346 H  HH21 . ARG A 1 357 ? 145.992 199.234 130.514 1.00 91.03  ? 368 ARG A HH21 1 
ATOM   5347 H  HH22 . ARG A 1 357 ? 145.368 197.990 129.981 1.00 90.61  ? 368 ARG A HH22 1 
ATOM   5348 N  N    . ASP A 1 358 ? 147.670 201.422 135.223 1.00 104.72 ? 369 ASP A N    1 
ATOM   5349 C  CA   . ASP A 1 358 ? 149.036 201.817 134.903 1.00 107.08 ? 369 ASP A CA   1 
ATOM   5350 C  C    . ASP A 1 358 ? 149.810 202.154 136.170 1.00 109.35 ? 369 ASP A C    1 
ATOM   5351 O  O    . ASP A 1 358 ? 150.973 201.762 136.320 1.00 109.17 ? 369 ASP A O    1 
ATOM   5352 C  CB   . ASP A 1 358 ? 149.026 203.010 133.949 1.00 106.57 ? 369 ASP A CB   1 
ATOM   5353 C  CG   . ASP A 1 358 ? 148.492 202.654 132.576 1.00 107.41 ? 369 ASP A CG   1 
ATOM   5354 O  OD1  . ASP A 1 358 ? 148.372 201.448 132.275 1.00 107.19 ? 369 ASP A OD1  1 
ATOM   5355 O  OD2  . ASP A 1 358 ? 148.191 203.582 131.796 1.00 107.20 ? 369 ASP A OD2  1 
ATOM   5356 H  H    . ASP A 1 358 ? 147.060 201.926 134.886 1.00 105.58 ? 369 ASP A H    1 
ATOM   5357 H  HA   . ASP A 1 358 ? 149.485 201.079 134.462 1.00 106.45 ? 369 ASP A HA   1 
ATOM   5358 H  HB2  . ASP A 1 358 ? 148.461 203.705 134.321 1.00 106.32 ? 369 ASP A HB2  1 
ATOM   5359 H  HB3  . ASP A 1 358 ? 149.933 203.338 133.844 1.00 107.03 ? 369 ASP A HB3  1 
ATOM   5360 N  N    . GLN A 1 359 ? 149.176 202.875 137.097 1.00 115.41 ? 370 GLN A N    1 
ATOM   5361 C  CA   . GLN A 1 359 ? 149.840 203.212 138.353 1.00 115.37 ? 370 GLN A CA   1 
ATOM   5362 C  C    . GLN A 1 359 ? 150.182 201.958 139.152 1.00 115.01 ? 370 GLN A C    1 
ATOM   5363 O  O    . GLN A 1 359 ? 151.291 201.833 139.687 1.00 117.30 ? 370 GLN A O    1 
ATOM   5364 C  CB   . GLN A 1 359 ? 148.951 204.144 139.176 1.00 115.16 ? 370 GLN A CB   1 
ATOM   5365 C  CG   . GLN A 1 359 ? 148.995 205.596 138.730 1.00 118.21 ? 370 GLN A CG   1 
ATOM   5366 C  CD   . GLN A 1 359 ? 150.279 206.292 139.138 1.00 117.86 ? 370 GLN A CD   1 
ATOM   5367 O  OE1  . GLN A 1 359 ? 151.053 206.739 138.291 1.00 113.71 ? 370 GLN A OE1  1 
ATOM   5368 N  NE2  . GLN A 1 359 ? 150.508 206.392 140.442 1.00 116.39 ? 370 GLN A NE2  1 
ATOM   5369 H  H    . GLN A 1 359 ? 148.375 203.176 137.022 1.00 114.21 ? 370 GLN A H    1 
ATOM   5370 H  HA   . GLN A 1 359 ? 150.667 203.679 138.158 1.00 115.53 ? 370 GLN A HA   1 
ATOM   5371 H  HB2  . GLN A 1 359 ? 148.032 203.841 139.105 1.00 114.29 ? 370 GLN A HB2  1 
ATOM   5372 H  HB3  . GLN A 1 359 ? 149.237 204.109 140.102 1.00 115.35 ? 370 GLN A HB3  1 
ATOM   5373 H  HG2  . GLN A 1 359 ? 148.927 205.633 137.764 1.00 115.20 ? 370 GLN A HG2  1 
ATOM   5374 H  HG3  . GLN A 1 359 ? 148.254 206.074 139.134 1.00 115.56 ? 370 GLN A HG3  1 
ATOM   5375 H  HE21 . GLN A 1 359 ? 149.943 206.069 141.003 1.00 115.74 ? 370 GLN A HE21 1 
ATOM   5376 H  HE22 . GLN A 1 359 ? 151.222 206.779 140.725 1.00 115.29 ? 370 GLN A HE22 1 
ATOM   5377 N  N    . VAL A 1 360 ? 149.244 201.015 139.240 1.00 103.53 ? 371 VAL A N    1 
ATOM   5378 C  CA   . VAL A 1 360 ? 149.483 199.804 140.019 1.00 103.37 ? 371 VAL A CA   1 
ATOM   5379 C  C    . VAL A 1 360 ? 150.543 198.940 139.347 1.00 102.09 ? 371 VAL A C    1 
ATOM   5380 O  O    . VAL A 1 360 ? 151.359 198.302 140.020 1.00 101.60 ? 371 VAL A O    1 
ATOM   5381 C  CB   . VAL A 1 360 ? 148.169 199.031 140.230 1.00 102.70 ? 371 VAL A CB   1 
ATOM   5382 C  CG1  . VAL A 1 360 ? 148.398 197.839 141.149 1.00 98.92  ? 371 VAL A CG1  1 
ATOM   5383 C  CG2  . VAL A 1 360 ? 147.096 199.945 140.811 1.00 104.95 ? 371 VAL A CG2  1 
ATOM   5384 H  H    . VAL A 1 360 ? 148.472 201.053 138.863 1.00 102.16 ? 371 VAL A H    1 
ATOM   5385 H  HA   . VAL A 1 360 ? 149.819 200.056 140.892 1.00 102.04 ? 371 VAL A HA   1 
ATOM   5386 H  HB   . VAL A 1 360 ? 147.853 198.699 139.375 1.00 101.47 ? 371 VAL A HB   1 
ATOM   5387 H  HG11 . VAL A 1 360 ? 147.558 197.369 141.269 1.00 100.54 ? 371 VAL A HG11 1 
ATOM   5388 H  HG12 . VAL A 1 360 ? 149.054 197.246 140.751 1.00 101.06 ? 371 VAL A HG12 1 
ATOM   5389 H  HG13 . VAL A 1 360 ? 148.721 198.161 142.005 1.00 100.91 ? 371 VAL A HG13 1 
ATOM   5390 H  HG21 . VAL A 1 360 ? 146.334 199.953 140.213 1.00 101.68 ? 371 VAL A HG21 1 
ATOM   5391 H  HG22 . VAL A 1 360 ? 146.830 199.606 141.680 1.00 101.56 ? 371 VAL A HG22 1 
ATOM   5392 H  HG23 . VAL A 1 360 ? 147.450 200.843 140.903 1.00 102.07 ? 371 VAL A HG23 1 
ATOM   5393 N  N    . SER A 1 361 ? 150.548 198.898 138.014 1.00 102.26 ? 372 SER A N    1 
ATOM   5394 C  CA   . SER A 1 361 ? 151.577 198.152 137.300 1.00 105.80 ? 372 SER A CA   1 
ATOM   5395 C  C    . SER A 1 361 ? 152.945 198.790 137.494 1.00 105.53 ? 372 SER A C    1 
ATOM   5396 O  O    . SER A 1 361 ? 153.953 198.087 137.598 1.00 103.94 ? 372 SER A O    1 
ATOM   5397 C  CB   . SER A 1 361 ? 151.226 198.066 135.815 1.00 106.12 ? 372 SER A CB   1 
ATOM   5398 O  OG   . SER A 1 361 ? 152.057 197.133 135.148 1.00 106.16 ? 372 SER A OG   1 
ATOM   5399 H  H    . SER A 1 361 ? 149.973 199.289 137.508 1.00 103.76 ? 372 SER A H    1 
ATOM   5400 H  HA   . SER A 1 361 ? 151.614 197.249 137.653 1.00 104.55 ? 372 SER A HA   1 
ATOM   5401 H  HB2  . SER A 1 361 ? 150.302 197.784 135.727 1.00 104.45 ? 372 SER A HB2  1 
ATOM   5402 H  HB3  . SER A 1 361 ? 151.345 198.940 135.411 1.00 104.51 ? 372 SER A HB3  1 
ATOM   5403 H  HG   . SER A 1 361 ? 151.836 197.077 134.340 1.00 104.38 ? 372 SER A HG   1 
ATOM   5404 N  N    . PHE A 1 362 ? 153.002 200.122 137.541 1.00 115.61 ? 373 PHE A N    1 
ATOM   5405 C  CA   . PHE A 1 362 ? 154.257 200.795 137.857 1.00 115.72 ? 373 PHE A CA   1 
ATOM   5406 C  C    . PHE A 1 362 ? 154.719 200.448 139.266 1.00 115.82 ? 373 PHE A C    1 
ATOM   5407 O  O    . PHE A 1 362 ? 155.912 200.223 139.502 1.00 116.68 ? 373 PHE A O    1 
ATOM   5408 C  CB   . PHE A 1 362 ? 154.090 202.307 137.702 1.00 116.94 ? 373 PHE A CB   1 
ATOM   5409 C  CG   . PHE A 1 362 ? 155.348 203.085 137.957 1.00 116.22 ? 373 PHE A CG   1 
ATOM   5410 C  CD1  . PHE A 1 362 ? 156.341 203.156 136.994 1.00 117.44 ? 373 PHE A CD1  1 
ATOM   5411 C  CD2  . PHE A 1 362 ? 155.537 203.748 139.158 1.00 116.53 ? 373 PHE A CD2  1 
ATOM   5412 C  CE1  . PHE A 1 362 ? 157.500 203.873 137.224 1.00 117.35 ? 373 PHE A CE1  1 
ATOM   5413 C  CE2  . PHE A 1 362 ? 156.694 204.466 139.394 1.00 117.94 ? 373 PHE A CE2  1 
ATOM   5414 C  CZ   . PHE A 1 362 ? 157.676 204.529 138.426 1.00 117.62 ? 373 PHE A CZ   1 
ATOM   5415 H  H    . PHE A 1 362 ? 152.338 200.650 137.396 1.00 115.75 ? 373 PHE A H    1 
ATOM   5416 H  HA   . PHE A 1 362 ? 154.940 200.502 137.234 1.00 116.09 ? 373 PHE A HA   1 
ATOM   5417 H  HB2  . PHE A 1 362 ? 153.801 202.498 136.796 1.00 116.48 ? 373 PHE A HB2  1 
ATOM   5418 H  HB3  . PHE A 1 362 ? 153.420 202.613 138.333 1.00 116.45 ? 373 PHE A HB3  1 
ATOM   5419 H  HD1  . PHE A 1 362 ? 156.226 202.716 136.183 1.00 116.70 ? 373 PHE A HD1  1 
ATOM   5420 H  HD2  . PHE A 1 362 ? 154.879 203.709 139.813 1.00 116.40 ? 373 PHE A HD2  1 
ATOM   5421 H  HE1  . PHE A 1 362 ? 158.160 203.913 136.571 1.00 116.42 ? 373 PHE A HE1  1 
ATOM   5422 H  HE2  . PHE A 1 362 ? 156.811 204.907 140.204 1.00 116.58 ? 373 PHE A HE2  1 
ATOM   5423 H  HZ   . PHE A 1 362 ? 158.456 205.011 138.583 1.00 116.44 ? 373 PHE A HZ   1 
ATOM   5424 N  N    . LEU A 1 363 ? 153.786 200.406 140.219 1.00 113.60 ? 374 LEU A N    1 
ATOM   5425 C  CA   . LEU A 1 363 ? 154.140 200.006 141.577 1.00 114.98 ? 374 LEU A CA   1 
ATOM   5426 C  C    . LEU A 1 363 ? 154.672 198.577 141.607 1.00 113.37 ? 374 LEU A C    1 
ATOM   5427 O  O    . LEU A 1 363 ? 155.654 198.284 142.297 1.00 114.43 ? 374 LEU A O    1 
ATOM   5428 C  CB   . LEU A 1 363 ? 152.929 200.147 142.499 1.00 115.02 ? 374 LEU A CB   1 
ATOM   5429 C  CG   . LEU A 1 363 ? 152.461 201.579 142.769 1.00 114.46 ? 374 LEU A CG   1 
ATOM   5430 C  CD1  . LEU A 1 363 ? 151.009 201.598 143.220 1.00 111.79 ? 374 LEU A CD1  1 
ATOM   5431 C  CD2  . LEU A 1 363 ? 153.353 202.247 143.804 1.00 113.38 ? 374 LEU A CD2  1 
ATOM   5432 H  H    . LEU A 1 363 ? 152.956 200.600 140.106 1.00 113.25 ? 374 LEU A H    1 
ATOM   5433 H  HA   . LEU A 1 363 ? 154.838 200.592 141.908 1.00 113.78 ? 374 LEU A HA   1 
ATOM   5434 H  HB2  . LEU A 1 363 ? 152.184 199.669 142.101 1.00 113.22 ? 374 LEU A HB2  1 
ATOM   5435 H  HB3  . LEU A 1 363 ? 153.147 199.747 143.356 1.00 113.76 ? 374 LEU A HB3  1 
ATOM   5436 H  HG   . LEU A 1 363 ? 152.525 202.090 141.947 1.00 113.53 ? 374 LEU A HG   1 
ATOM   5437 H  HD11 . LEU A 1 363 ? 150.828 202.442 143.663 1.00 113.14 ? 374 LEU A HD11 1 
ATOM   5438 H  HD12 . LEU A 1 363 ? 150.435 201.504 142.445 1.00 112.81 ? 374 LEU A HD12 1 
ATOM   5439 H  HD13 . LEU A 1 363 ? 150.860 200.864 143.836 1.00 113.06 ? 374 LEU A HD13 1 
ATOM   5440 H  HD21 . LEU A 1 363 ? 153.043 203.155 143.947 1.00 113.52 ? 374 LEU A HD21 1 
ATOM   5441 H  HD22 . LEU A 1 363 ? 153.304 201.746 144.633 1.00 113.36 ? 374 LEU A HD22 1 
ATOM   5442 H  HD23 . LEU A 1 363 ? 154.265 202.257 143.476 1.00 113.35 ? 374 LEU A HD23 1 
ATOM   5443 N  N    . ILE A 1 364 ? 154.032 197.674 140.863 1.00 101.88 ? 375 ILE A N    1 
ATOM   5444 C  CA   . ILE A 1 364 ? 154.494 196.290 140.804 1.00 102.49 ? 375 ILE A CA   1 
ATOM   5445 C  C    . ILE A 1 364 ? 155.866 196.215 140.146 1.00 105.35 ? 375 ILE A C    1 
ATOM   5446 O  O    . ILE A 1 364 ? 156.709 195.396 140.529 1.00 103.53 ? 375 ILE A O    1 
ATOM   5447 C  CB   . ILE A 1 364 ? 153.463 195.417 140.066 1.00 103.80 ? 375 ILE A CB   1 
ATOM   5448 C  CG1  . ILE A 1 364 ? 152.166 195.308 140.877 1.00 105.14 ? 375 ILE A CG1  1 
ATOM   5449 C  CG2  . ILE A 1 364 ? 154.037 194.035 139.784 1.00 104.39 ? 375 ILE A CG2  1 
ATOM   5450 C  CD1  . ILE A 1 364 ? 152.292 194.516 142.171 1.00 102.97 ? 375 ILE A CD1  1 
ATOM   5451 H  H    . ILE A 1 364 ? 153.333 197.836 140.389 1.00 103.80 ? 375 ILE A H    1 
ATOM   5452 H  HA   . ILE A 1 364 ? 154.585 195.952 141.708 1.00 103.70 ? 375 ILE A HA   1 
ATOM   5453 H  HB   . ILE A 1 364 ? 153.257 195.840 139.218 1.00 104.03 ? 375 ILE A HB   1 
ATOM   5454 H  HG12 . ILE A 1 364 ? 151.868 196.201 141.110 1.00 104.18 ? 375 ILE A HG12 1 
ATOM   5455 H  HG13 . ILE A 1 364 ? 151.494 194.872 140.330 1.00 103.98 ? 375 ILE A HG13 1 
ATOM   5456 H  HG21 . ILE A 1 364 ? 153.307 193.426 139.591 1.00 103.87 ? 375 ILE A HG21 1 
ATOM   5457 H  HG22 . ILE A 1 364 ? 154.632 194.087 139.020 1.00 104.08 ? 375 ILE A HG22 1 
ATOM   5458 H  HG23 . ILE A 1 364 ? 154.523 193.729 140.565 1.00 103.79 ? 375 ILE A HG23 1 
ATOM   5459 H  HD11 . ILE A 1 364 ? 151.429 194.504 142.614 1.00 103.10 ? 375 ILE A HD11 1 
ATOM   5460 H  HD12 . ILE A 1 364 ? 152.567 193.609 141.966 1.00 103.54 ? 375 ILE A HD12 1 
ATOM   5461 H  HD13 . ILE A 1 364 ? 152.948 194.941 142.744 1.00 103.66 ? 375 ILE A HD13 1 
ATOM   5462 N  N    . ARG A 1 365 ? 156.108 197.052 139.136 1.00 121.93 ? 376 ARG A N    1 
ATOM   5463 C  CA   . ARG A 1 365 ? 157.422 197.095 138.505 1.00 122.86 ? 376 ARG A CA   1 
ATOM   5464 C  C    . ARG A 1 365 ? 158.486 197.548 139.496 1.00 121.70 ? 376 ARG A C    1 
ATOM   5465 O  O    . ARG A 1 365 ? 159.581 196.979 139.550 1.00 119.96 ? 376 ARG A O    1 
ATOM   5466 C  CB   . ARG A 1 365 ? 157.389 198.024 137.292 1.00 121.38 ? 376 ARG A CB   1 
ATOM   5467 H  H    . ARG A 1 365 ? 155.533 197.598 138.802 1.00 120.01 ? 376 ARG A H    1 
ATOM   5468 H  HA   . ARG A 1 365 ? 157.649 196.208 138.189 1.00 120.83 ? 376 ARG A HA   1 
ATOM   5469 N  N    . LYS A 1 366 ? 158.180 198.574 140.290 1.00 128.14 ? 377 LYS A N    1 
ATOM   5470 C  CA   . LYS A 1 366 ? 159.117 199.006 141.322 1.00 128.07 ? 377 LYS A CA   1 
ATOM   5471 C  C    . LYS A 1 366 ? 159.357 197.894 142.336 1.00 126.85 ? 377 LYS A C    1 
ATOM   5472 O  O    . LYS A 1 366 ? 160.494 197.670 142.769 1.00 127.03 ? 377 LYS A O    1 
ATOM   5473 C  CB   . LYS A 1 366 ? 158.592 200.263 142.018 1.00 129.52 ? 377 LYS A CB   1 
ATOM   5474 C  CG   . LYS A 1 366 ? 158.424 201.473 141.102 1.00 128.89 ? 377 LYS A CG   1 
ATOM   5475 C  CD   . LYS A 1 366 ? 159.746 201.964 140.518 1.00 129.31 ? 377 LYS A CD   1 
ATOM   5476 C  CE   . LYS A 1 366 ? 160.655 202.565 141.581 1.00 129.99 ? 377 LYS A CE   1 
ATOM   5477 N  NZ   . LYS A 1 366 ? 160.061 203.780 142.204 1.00 130.56 ? 377 LYS A NZ   1 
ATOM   5478 H  H    . LYS A 1 366 ? 157.450 199.027 140.254 1.00 127.70 ? 377 LYS A H    1 
ATOM   5479 H  HA   . LYS A 1 366 ? 159.968 199.217 140.908 1.00 128.11 ? 377 LYS A HA   1 
ATOM   5480 H  HB2  . LYS A 1 366 ? 157.723 200.062 142.397 1.00 128.08 ? 377 LYS A HB2  1 
ATOM   5481 H  HB3  . LYS A 1 366 ? 159.206 200.506 142.727 1.00 128.56 ? 377 LYS A HB3  1 
ATOM   5482 H  HG2  . LYS A 1 366 ? 157.846 201.232 140.362 1.00 128.01 ? 377 LYS A HG2  1 
ATOM   5483 H  HG3  . LYS A 1 366 ? 158.029 202.200 141.608 1.00 128.10 ? 377 LYS A HG3  1 
ATOM   5484 H  HD2  . LYS A 1 366 ? 160.213 201.224 140.102 1.00 128.46 ? 377 LYS A HD2  1 
ATOM   5485 H  HD3  . LYS A 1 366 ? 159.562 202.651 139.858 1.00 128.49 ? 377 LYS A HD3  1 
ATOM   5486 H  HE2  . LYS A 1 366 ? 160.815 201.912 142.279 1.00 128.75 ? 377 LYS A HE2  1 
ATOM   5487 H  HE3  . LYS A 1 366 ? 161.495 202.821 141.168 1.00 128.73 ? 377 LYS A HE3  1 
ATOM   5488 H  HZ1  . LYS A 1 366 ? 159.308 203.567 142.629 1.00 128.67 ? 377 LYS A HZ1  1 
ATOM   5489 H  HZ2  . LYS A 1 366 ? 159.878 204.385 141.578 1.00 128.62 ? 377 LYS A HZ2  1 
ATOM   5490 H  HZ3  . LYS A 1 366 ? 160.632 204.132 142.789 1.00 128.88 ? 377 LYS A HZ3  1 
ATOM   5491 N  N    . GLU A 1 367 ? 158.295 197.186 142.723 1.00 125.70 ? 378 GLU A N    1 
ATOM   5492 C  CA   . GLU A 1 367 ? 158.438 196.101 143.688 1.00 127.46 ? 378 GLU A CA   1 
ATOM   5493 C  C    . GLU A 1 367 ? 159.322 194.986 143.142 1.00 129.08 ? 378 GLU A C    1 
ATOM   5494 O  O    . GLU A 1 367 ? 160.190 194.468 143.852 1.00 130.05 ? 378 GLU A O    1 
ATOM   5495 C  CB   . GLU A 1 367 ? 157.062 195.554 144.066 1.00 126.74 ? 378 GLU A CB   1 
ATOM   5496 H  H    . GLU A 1 367 ? 157.491 197.313 142.444 1.00 126.76 ? 378 GLU A H    1 
ATOM   5497 H  HA   . GLU A 1 367 ? 158.854 196.446 144.493 1.00 127.57 ? 378 GLU A HA   1 
ATOM   5498 N  N    . VAL A 1 368 ? 159.115 194.599 141.881 1.00 133.74 ? 379 VAL A N    1 
ATOM   5499 C  CA   . VAL A 1 368 ? 159.920 193.530 141.300 1.00 136.26 ? 379 VAL A CA   1 
ATOM   5500 C  C    . VAL A 1 368 ? 161.359 193.990 141.099 1.00 138.13 ? 379 VAL A C    1 
ATOM   5501 O  O    . VAL A 1 368 ? 162.295 193.193 141.226 1.00 137.27 ? 379 VAL A O    1 
ATOM   5502 C  CB   . VAL A 1 368 ? 159.286 193.029 139.986 1.00 135.38 ? 379 VAL A CB   1 
ATOM   5503 C  CG1  . VAL A 1 368 ? 159.371 194.080 138.901 1.00 134.76 ? 379 VAL A CG1  1 
ATOM   5504 C  CG2  . VAL A 1 368 ? 159.942 191.737 139.537 1.00 134.74 ? 379 VAL A CG2  1 
ATOM   5505 H  H    . VAL A 1 368 ? 158.525 194.934 141.353 1.00 133.16 ? 379 VAL A H    1 
ATOM   5506 H  HA   . VAL A 1 368 ? 159.936 192.784 141.919 1.00 134.56 ? 379 VAL A HA   1 
ATOM   5507 H  HB   . VAL A 1 368 ? 158.348 192.843 140.145 1.00 134.28 ? 379 VAL A HB   1 
ATOM   5508 H  HG11 . VAL A 1 368 ? 158.944 193.739 138.099 1.00 134.26 ? 379 VAL A HG11 1 
ATOM   5509 H  HG12 . VAL A 1 368 ? 158.903 194.864 139.212 1.00 133.68 ? 379 VAL A HG12 1 
ATOM   5510 H  HG13 . VAL A 1 368 ? 160.299 194.290 138.717 1.00 134.48 ? 379 VAL A HG13 1 
ATOM   5511 H  HG21 . VAL A 1 368 ? 159.585 191.485 138.671 1.00 134.65 ? 379 VAL A HG21 1 
ATOM   5512 H  HG22 . VAL A 1 368 ? 160.901 191.868 139.475 1.00 134.58 ? 379 VAL A HG22 1 
ATOM   5513 H  HG23 . VAL A 1 368 ? 159.741 191.051 140.191 1.00 134.67 ? 379 VAL A HG23 1 
ATOM   5514 N  N    . ALA A 1 369 ? 161.567 195.271 140.781 1.00 147.35 ? 380 ALA A N    1 
ATOM   5515 C  CA   . ALA A 1 369 ? 162.927 195.795 140.709 1.00 147.73 ? 380 ALA A CA   1 
ATOM   5516 C  C    . ALA A 1 369 ? 163.609 195.723 142.069 1.00 146.47 ? 380 ALA A C    1 
ATOM   5517 O  O    . ALA A 1 369 ? 164.790 195.369 142.165 1.00 143.74 ? 380 ALA A O    1 
ATOM   5518 C  CB   . ALA A 1 369 ? 162.908 197.232 140.191 1.00 147.42 ? 380 ALA A CB   1 
ATOM   5519 H  H    . ALA A 1 369 ? 160.950 195.844 140.606 1.00 144.47 ? 380 ALA A H    1 
ATOM   5520 H  HA   . ALA A 1 369 ? 163.441 195.257 140.087 1.00 145.54 ? 380 ALA A HA   1 
ATOM   5521 H  HB1  . ALA A 1 369 ? 163.819 197.564 140.148 1.00 145.75 ? 380 ALA A HB1  1 
ATOM   5522 H  HB2  . ALA A 1 369 ? 162.510 197.243 139.307 1.00 145.54 ? 380 ALA A HB2  1 
ATOM   5523 H  HB3  . ALA A 1 369 ? 162.385 197.779 140.797 1.00 145.25 ? 380 ALA A HB3  1 
ATOM   5524 N  N    . LYS A 1 370 ? 162.878 196.055 143.136 1.00 141.28 ? 381 LYS A N    1 
ATOM   5525 C  CA   . LYS A 1 370 ? 163.431 195.919 144.480 1.00 140.04 ? 381 LYS A CA   1 
ATOM   5526 C  C    . LYS A 1 370 ? 163.747 194.462 144.795 1.00 140.80 ? 381 LYS A C    1 
ATOM   5527 O  O    . LYS A 1 370 ? 164.776 194.161 145.411 1.00 141.18 ? 381 LYS A O    1 
ATOM   5528 C  CB   . LYS A 1 370 ? 162.456 196.490 145.509 1.00 139.16 ? 381 LYS A CB   1 
ATOM   5529 C  CG   . LYS A 1 370 ? 162.288 198.002 145.434 1.00 139.57 ? 381 LYS A CG   1 
ATOM   5530 C  CD   . LYS A 1 370 ? 160.905 198.443 145.900 1.00 139.42 ? 381 LYS A CD   1 
ATOM   5531 C  CE   . LYS A 1 370 ? 160.498 199.771 145.280 1.00 139.43 ? 381 LYS A CE   1 
ATOM   5532 N  NZ   . LYS A 1 370 ? 159.023 199.976 145.324 1.00 140.06 ? 381 LYS A NZ   1 
ATOM   5533 H  H    . LYS A 1 370 ? 162.073 196.357 143.108 1.00 139.61 ? 381 LYS A H    1 
ATOM   5534 H  HA   . LYS A 1 370 ? 164.257 196.425 144.535 1.00 139.79 ? 381 LYS A HA   1 
ATOM   5535 H  HB2  . LYS A 1 370 ? 161.587 196.083 145.369 1.00 139.31 ? 381 LYS A HB2  1 
ATOM   5536 H  HB3  . LYS A 1 370 ? 162.779 196.273 146.398 1.00 139.63 ? 381 LYS A HB3  1 
ATOM   5537 H  HG2  . LYS A 1 370 ? 162.949 198.424 146.005 1.00 139.77 ? 381 LYS A HG2  1 
ATOM   5538 H  HG3  . LYS A 1 370 ? 162.407 198.288 144.515 1.00 139.49 ? 381 LYS A HG3  1 
ATOM   5539 H  HD2  . LYS A 1 370 ? 160.248 197.778 145.643 1.00 139.47 ? 381 LYS A HD2  1 
ATOM   5540 H  HD3  . LYS A 1 370 ? 160.913 198.549 146.864 1.00 139.50 ? 381 LYS A HD3  1 
ATOM   5541 H  HE2  . LYS A 1 370 ? 160.918 200.494 145.771 1.00 139.46 ? 381 LYS A HE2  1 
ATOM   5542 H  HE3  . LYS A 1 370 ? 160.776 199.791 144.351 1.00 139.35 ? 381 LYS A HE3  1 
ATOM   5543 H  HZ1  . LYS A 1 370 ? 158.613 199.330 144.870 1.00 139.49 ? 381 LYS A HZ1  1 
ATOM   5544 H  HZ2  . LYS A 1 370 ? 158.739 199.963 146.167 1.00 139.66 ? 381 LYS A HZ2  1 
ATOM   5545 H  HZ3  . LYS A 1 370 ? 158.815 200.762 144.961 1.00 139.41 ? 381 LYS A HZ3  1 
ATOM   5546 N  N    . LEU A 1 371 ? 162.866 193.546 144.391 1.00 145.79 ? 382 LEU A N    1 
ATOM   5547 C  CA   . LEU A 1 371 ? 163.130 192.123 144.586 1.00 145.73 ? 382 LEU A CA   1 
ATOM   5548 C  C    . LEU A 1 371 ? 164.418 191.709 143.887 1.00 143.26 ? 382 LEU A C    1 
ATOM   5549 O  O    . LEU A 1 371 ? 165.266 191.025 144.471 1.00 140.57 ? 382 LEU A O    1 
ATOM   5550 C  CB   . LEU A 1 371 ? 161.953 191.293 144.067 1.00 146.37 ? 382 LEU A CB   1 
ATOM   5551 C  CG   . LEU A 1 371 ? 160.871 190.907 145.078 1.00 146.70 ? 382 LEU A CG   1 
ATOM   5552 C  CD1  . LEU A 1 371 ? 160.005 192.098 145.446 1.00 144.54 ? 382 LEU A CD1  1 
ATOM   5553 C  CD2  . LEU A 1 371 ? 160.018 189.775 144.525 1.00 144.94 ? 382 LEU A CD2  1 
ATOM   5554 H  H    . LEU A 1 371 ? 162.117 193.722 144.007 1.00 143.95 ? 382 LEU A H    1 
ATOM   5555 H  HA   . LEU A 1 371 ? 163.231 191.948 145.533 1.00 144.17 ? 382 LEU A HA   1 
ATOM   5556 H  HB2  . LEU A 1 371 ? 161.518 191.794 143.360 1.00 144.08 ? 382 LEU A HB2  1 
ATOM   5557 H  HB3  . LEU A 1 371 ? 162.307 190.467 143.700 1.00 144.22 ? 382 LEU A HB3  1 
ATOM   5558 H  HG   . LEU A 1 371 ? 161.300 190.587 145.885 1.00 144.36 ? 382 LEU A HG   1 
ATOM   5559 H  HD11 . LEU A 1 371 ? 159.443 191.858 146.200 1.00 143.97 ? 382 LEU A HD11 1 
ATOM   5560 H  HD12 . LEU A 1 371 ? 160.578 192.844 145.684 1.00 143.71 ? 382 LEU A HD12 1 
ATOM   5561 H  HD13 . LEU A 1 371 ? 159.453 192.333 144.684 1.00 143.90 ? 382 LEU A HD13 1 
ATOM   5562 H  HD21 . LEU A 1 371 ? 159.330 189.553 145.171 1.00 144.21 ? 382 LEU A HD21 1 
ATOM   5563 H  HD22 . LEU A 1 371 ? 159.610 190.065 143.694 1.00 144.14 ? 382 LEU A HD22 1 
ATOM   5564 H  HD23 . LEU A 1 371 ? 160.583 189.003 144.364 1.00 144.31 ? 382 LEU A HD23 1 
ATOM   5565 N  N    . GLN A 1 372 ? 164.583 192.123 142.630 1.00 141.57 ? 383 GLN A N    1 
ATOM   5566 C  CA   . GLN A 1 372 ? 165.801 191.794 141.899 1.00 142.17 ? 383 GLN A CA   1 
ATOM   5567 C  C    . GLN A 1 372 ? 167.024 192.383 142.588 1.00 143.03 ? 383 GLN A C    1 
ATOM   5568 O  O    . GLN A 1 372 ? 168.072 191.734 142.675 1.00 143.19 ? 383 GLN A O    1 
ATOM   5569 C  CB   . GLN A 1 372 ? 165.699 192.297 140.459 1.00 140.87 ? 383 GLN A CB   1 
ATOM   5570 H  H    . GLN A 1 372 ? 164.013 192.590 142.186 1.00 141.79 ? 383 GLN A H    1 
ATOM   5571 H  HA   . GLN A 1 372 ? 165.905 190.829 141.874 1.00 141.86 ? 383 GLN A HA   1 
ATOM   5572 N  N    . GLU A 1 373 ? 166.907 193.616 143.084 1.00 146.17 ? 384 GLU A N    1 
ATOM   5573 C  CA   . GLU A 1 373 ? 168.027 194.244 143.775 1.00 147.40 ? 384 GLU A CA   1 
ATOM   5574 C  C    . GLU A 1 373 ? 168.405 193.470 145.032 1.00 148.77 ? 384 GLU A C    1 
ATOM   5575 O  O    . GLU A 1 373 ? 169.593 193.265 145.309 1.00 148.52 ? 384 GLU A O    1 
ATOM   5576 C  CB   . GLU A 1 373 ? 167.677 195.690 144.126 1.00 147.10 ? 384 GLU A CB   1 
ATOM   5577 C  CG   . GLU A 1 373 ? 167.583 196.618 142.926 1.00 146.38 ? 384 GLU A CG   1 
ATOM   5578 C  CD   . GLU A 1 373 ? 166.685 197.812 143.183 1.00 146.53 ? 384 GLU A CD   1 
ATOM   5579 O  OE1  . GLU A 1 373 ? 166.914 198.527 144.181 1.00 147.57 ? 384 GLU A OE1  1 
ATOM   5580 O  OE2  . GLU A 1 373 ? 165.748 198.036 142.387 1.00 144.91 ? 384 GLU A OE2  1 
ATOM   5581 H  H    . GLU A 1 373 ? 166.199 194.102 143.034 1.00 146.27 ? 384 GLU A H    1 
ATOM   5582 H  HA   . GLU A 1 373 ? 168.797 194.256 143.186 1.00 146.80 ? 384 GLU A HA   1 
ATOM   5583 H  HB2  . GLU A 1 373 ? 166.817 195.702 144.576 1.00 146.77 ? 384 GLU A HB2  1 
ATOM   5584 H  HB3  . GLU A 1 373 ? 168.360 196.041 144.718 1.00 146.74 ? 384 GLU A HB3  1 
ATOM   5585 H  HG2  . GLU A 1 373 ? 168.469 196.949 142.713 1.00 146.76 ? 384 GLU A HG2  1 
ATOM   5586 H  HG3  . GLU A 1 373 ? 167.221 196.126 142.173 1.00 146.59 ? 384 GLU A HG3  1 
ATOM   5587 N  N    . LYS A 1 374 ? 167.411 193.031 145.806 1.00 153.68 ? 385 LYS A N    1 
ATOM   5588 C  CA   . LYS A 1 374 ? 167.647 192.393 147.096 1.00 152.98 ? 385 LYS A CA   1 
ATOM   5589 C  C    . LYS A 1 374 ? 167.265 190.918 147.093 1.00 152.81 ? 385 LYS A C    1 
ATOM   5590 O  O    . LYS A 1 374 ? 168.104 190.063 147.390 1.00 152.58 ? 385 LYS A O    1 
ATOM   5591 C  CB   . LYS A 1 374 ? 166.868 193.133 148.194 1.00 151.68 ? 385 LYS A CB   1 
ATOM   5592 C  CG   . LYS A 1 374 ? 166.820 194.646 148.031 1.00 151.21 ? 385 LYS A CG   1 
ATOM   5593 C  CD   . LYS A 1 374 ? 168.212 195.251 147.977 1.00 152.13 ? 385 LYS A CD   1 
ATOM   5594 C  CE   . LYS A 1 374 ? 168.203 196.695 148.450 1.00 151.60 ? 385 LYS A CE   1 
ATOM   5595 N  NZ   . LYS A 1 374 ? 168.127 196.796 149.934 1.00 150.22 ? 385 LYS A NZ   1 
ATOM   5596 H  H    . LYS A 1 374 ? 166.579 193.093 145.599 1.00 151.33 ? 385 LYS A H    1 
ATOM   5597 H  HA   . LYS A 1 374 ? 168.590 192.453 147.311 1.00 151.58 ? 385 LYS A HA   1 
ATOM   5598 H  HB2  . LYS A 1 374 ? 165.954 192.809 148.198 1.00 151.47 ? 385 LYS A HB2  1 
ATOM   5599 H  HB3  . LYS A 1 374 ? 167.285 192.944 149.050 1.00 151.49 ? 385 LYS A HB3  1 
ATOM   5600 H  HG2  . LYS A 1 374 ? 166.358 194.868 147.208 1.00 151.21 ? 385 LYS A HG2  1 
ATOM   5601 H  HG3  . LYS A 1 374 ? 166.353 195.031 148.789 1.00 151.42 ? 385 LYS A HG3  1 
ATOM   5602 H  HD2  . LYS A 1 374 ? 168.805 194.745 148.553 1.00 151.67 ? 385 LYS A HD2  1 
ATOM   5603 H  HD3  . LYS A 1 374 ? 168.535 195.235 147.063 1.00 151.47 ? 385 LYS A HD3  1 
ATOM   5604 H  HE2  . LYS A 1 374 ? 169.020 197.131 148.159 1.00 151.55 ? 385 LYS A HE2  1 
ATOM   5605 H  HE3  . LYS A 1 374 ? 167.431 197.148 148.077 1.00 151.57 ? 385 LYS A HE3  1 
ATOM   5606 H  HZ1  . LYS A 1 374 ? 168.838 196.406 150.302 1.00 151.33 ? 385 LYS A HZ1  1 
ATOM   5607 H  HZ2  . LYS A 1 374 ? 167.391 196.391 150.229 1.00 151.44 ? 385 LYS A HZ2  1 
ATOM   5608 H  HZ3  . LYS A 1 374 ? 168.105 197.651 150.180 1.00 151.40 ? 385 LYS A HZ3  1 
ATOM   5609 N  N    . ARG A 1 375 ? 166.012 190.592 146.766 1.00 151.46 ? 386 ARG A N    1 
ATOM   5610 C  CA   . ARG A 1 375 ? 165.579 189.199 146.824 1.00 151.70 ? 386 ARG A CA   1 
ATOM   5611 C  C    . ARG A 1 375 ? 166.348 188.339 145.829 1.00 150.56 ? 386 ARG A C    1 
ATOM   5612 O  O    . ARG A 1 375 ? 166.769 187.223 146.156 1.00 150.83 ? 386 ARG A O    1 
ATOM   5613 C  CB   . ARG A 1 375 ? 164.075 189.100 146.567 1.00 150.76 ? 386 ARG A CB   1 
ATOM   5614 C  CG   . ARG A 1 375 ? 163.213 189.279 147.811 1.00 151.27 ? 386 ARG A CG   1 
ATOM   5615 C  CD   . ARG A 1 375 ? 163.141 190.738 148.244 1.00 152.12 ? 386 ARG A CD   1 
ATOM   5616 N  NE   . ARG A 1 375 ? 162.369 190.923 149.468 1.00 150.97 ? 386 ARG A NE   1 
ATOM   5617 C  CZ   . ARG A 1 375 ? 161.065 190.701 149.581 1.00 149.76 ? 386 ARG A CZ   1 
ATOM   5618 N  NH1  . ARG A 1 375 ? 160.337 190.300 148.551 1.00 149.62 ? 386 ARG A NH1  1 
ATOM   5619 N  NH2  . ARG A 1 375 ? 160.475 190.892 150.757 1.00 148.29 ? 386 ARG A NH2  1 
ATOM   5620 H  H    . ARG A 1 375 ? 165.406 191.147 146.512 1.00 150.10 ? 386 ARG A H    1 
ATOM   5621 H  HA   . ARG A 1 375 ? 165.754 188.852 147.713 1.00 150.61 ? 386 ARG A HA   1 
ATOM   5622 H  HB2  . ARG A 1 375 ? 163.819 189.785 145.931 1.00 150.09 ? 386 ARG A HB2  1 
ATOM   5623 H  HB3  . ARG A 1 375 ? 163.880 188.224 146.198 1.00 150.28 ? 386 ARG A HB3  1 
ATOM   5624 H  HG2  . ARG A 1 375 ? 162.315 188.968 147.619 1.00 150.18 ? 386 ARG A HG2  1 
ATOM   5625 H  HG3  . ARG A 1 375 ? 163.595 188.766 148.540 1.00 150.45 ? 386 ARG A HG3  1 
ATOM   5626 H  HD2  . ARG A 1 375 ? 164.039 191.067 148.403 1.00 150.53 ? 386 ARG A HD2  1 
ATOM   5627 H  HD3  . ARG A 1 375 ? 162.715 191.256 147.545 1.00 150.42 ? 386 ARG A HD3  1 
ATOM   5628 H  HE   . ARG A 1 375 ? 162.775 191.260 150.147 1.00 150.31 ? 386 ARG A HE   1 
ATOM   5629 H  HH11 . ARG A 1 375 ? 160.703 190.174 147.785 1.00 150.13 ? 386 ARG A HH11 1 
ATOM   5630 H  HH12 . ARG A 1 375 ? 159.494 190.165 148.649 1.00 150.20 ? 386 ARG A HH12 1 
ATOM   5631 H  HH21 . ARG A 1 375 ? 160.938 191.153 151.433 1.00 150.09 ? 386 ARG A HH21 1 
ATOM   5632 H  HH22 . ARG A 1 375 ? 159.630 190.753 150.842 1.00 150.15 ? 386 ARG A HH22 1 
ATOM   5633 N  N    . GLY A 1 376 ? 166.543 188.840 144.613 1.00 136.83 ? 387 GLY A N    1 
ATOM   5634 C  CA   . GLY A 1 376 ? 167.253 188.071 143.603 1.00 136.39 ? 387 GLY A CA   1 
ATOM   5635 C  C    . GLY A 1 376 ? 166.585 186.755 143.274 1.00 137.52 ? 387 GLY A C    1 
ATOM   5636 O  O    . GLY A 1 376 ? 167.272 185.753 143.036 1.00 135.18 ? 387 GLY A O    1 
ATOM   5637 H  H    . GLY A 1 376 ? 166.276 189.614 144.351 1.00 137.21 ? 387 GLY A H    1 
ATOM   5638 H  HA2  . GLY A 1 376 ? 167.315 188.593 142.788 1.00 136.68 ? 387 GLY A HA2  1 
ATOM   5639 H  HA3  . GLY A 1 376 ? 168.153 187.886 143.915 1.00 136.85 ? 387 GLY A HA3  1 
ATOM   5640 N  N    . ASN A 1 377 ? 165.254 186.733 143.255 1.00 138.35 ? 388 ASN A N    1 
ATOM   5641 C  CA   . ASN A 1 377 ? 164.477 185.536 142.939 1.00 137.05 ? 388 ASN A CA   1 
ATOM   5642 C  C    . ASN A 1 377 ? 163.652 185.837 141.692 1.00 134.43 ? 388 ASN A C    1 
ATOM   5643 O  O    . ASN A 1 377 ? 162.620 186.510 141.768 1.00 133.25 ? 388 ASN A O    1 
ATOM   5644 C  CB   . ASN A 1 377 ? 163.589 185.132 144.113 1.00 135.58 ? 388 ASN A CB   1 
ATOM   5645 H  H    . ASN A 1 377 ? 164.765 187.419 143.427 1.00 136.11 ? 388 ASN A H    1 
ATOM   5646 H  HA   . ASN A 1 377 ? 165.076 184.800 142.741 1.00 135.86 ? 388 ASN A HA   1 
ATOM   5647 N  N    . LYS A 1 378 ? 164.109 185.333 140.545 1.00 119.71 ? 389 LYS A N    1 
ATOM   5648 C  CA   . LYS A 1 378 ? 163.405 185.593 139.294 1.00 119.92 ? 389 LYS A CA   1 
ATOM   5649 C  C    . LYS A 1 378 ? 162.010 184.983 139.313 1.00 120.20 ? 389 LYS A C    1 
ATOM   5650 O  O    . LYS A 1 378 ? 161.055 185.584 138.806 1.00 119.04 ? 389 LYS A O    1 
ATOM   5651 C  CB   . LYS A 1 378 ? 164.212 185.047 138.116 1.00 119.03 ? 389 LYS A CB   1 
ATOM   5652 H  H    . LYS A 1 378 ? 164.814 184.846 140.466 1.00 120.10 ? 389 LYS A H    1 
ATOM   5653 H  HA   . LYS A 1 378 ? 163.313 186.551 139.176 1.00 119.95 ? 389 LYS A HA   1 
ATOM   5654 N  N    . ALA A 1 379 ? 161.872 183.788 139.890 1.00 114.59 ? 390 ALA A N    1 
ATOM   5655 C  CA   . ALA A 1 379 ? 160.577 183.116 139.895 1.00 113.13 ? 390 ALA A CA   1 
ATOM   5656 C  C    . ALA A 1 379 ? 159.536 183.935 140.649 1.00 112.17 ? 390 ALA A C    1 
ATOM   5657 O  O    . ALA A 1 379 ? 158.451 184.206 140.128 1.00 109.73 ? 390 ALA A O    1 
ATOM   5658 C  CB   . ALA A 1 379 ? 160.712 181.723 140.507 1.00 110.93 ? 390 ALA A CB   1 
ATOM   5659 H  H    . ALA A 1 379 ? 162.503 183.353 140.280 1.00 111.41 ? 390 ALA A H    1 
ATOM   5660 H  HA   . ALA A 1 379 ? 160.272 183.013 138.980 1.00 110.50 ? 390 ALA A HA   1 
ATOM   5661 H  HB1  . ALA A 1 379 ? 159.852 181.276 140.466 1.00 109.17 ? 390 ALA A HB1  1 
ATOM   5662 H  HB2  . ALA A 1 379 ? 161.371 181.220 140.004 1.00 109.94 ? 390 ALA A HB2  1 
ATOM   5663 H  HB3  . ALA A 1 379 ? 160.996 181.812 141.430 1.00 109.93 ? 390 ALA A HB3  1 
ATOM   5664 N  N    . SER A 1 380 ? 159.854 184.356 141.876 1.00 110.55 ? 391 SER A N    1 
ATOM   5665 C  CA   . SER A 1 380 ? 158.907 185.163 142.642 1.00 109.86 ? 391 SER A CA   1 
ATOM   5666 C  C    . SER A 1 380 ? 158.741 186.552 142.037 1.00 110.11 ? 391 SER A C    1 
ATOM   5667 O  O    . SER A 1 380 ? 157.648 187.136 142.104 1.00 111.04 ? 391 SER A O    1 
ATOM   5668 C  CB   . SER A 1 380 ? 159.367 185.270 144.095 1.00 107.97 ? 391 SER A CB   1 
ATOM   5669 H  H    . SER A 1 380 ? 160.596 184.190 142.278 1.00 109.78 ? 391 SER A H    1 
ATOM   5670 H  HA   . SER A 1 380 ? 158.042 184.726 142.633 1.00 109.49 ? 391 SER A HA   1 
ATOM   5671 N  N    . ASP A 1 381 ? 159.810 187.096 141.454 1.00 118.62 ? 392 ASP A N    1 
ATOM   5672 C  CA   . ASP A 1 381 ? 159.712 188.390 140.792 1.00 121.02 ? 392 ASP A CA   1 
ATOM   5673 C  C    . ASP A 1 381 ? 158.687 188.345 139.669 1.00 122.66 ? 392 ASP A C    1 
ATOM   5674 O  O    . ASP A 1 381 ? 157.885 189.272 139.509 1.00 122.98 ? 392 ASP A O    1 
ATOM   5675 C  CB   . ASP A 1 381 ? 161.082 188.805 140.256 1.00 120.82 ? 392 ASP A CB   1 
ATOM   5676 H  H    . ASP A 1 381 ? 160.592 186.739 141.429 1.00 120.47 ? 392 ASP A H    1 
ATOM   5677 H  HA   . ASP A 1 381 ? 159.425 189.056 141.437 1.00 121.30 ? 392 ASP A HA   1 
ATOM   5678 N  N    . LYS A 1 382 ? 158.698 187.269 138.880 1.00 111.33 ? 393 LYS A N    1 
ATOM   5679 C  CA   . LYS A 1 382 ? 157.675 187.094 137.858 1.00 106.96 ? 393 LYS A CA   1 
ATOM   5680 C  C    . LYS A 1 382 ? 156.334 186.713 138.471 1.00 107.00 ? 393 LYS A C    1 
ATOM   5681 O  O    . LYS A 1 382 ? 155.287 187.013 137.894 1.00 104.37 ? 393 LYS A O    1 
ATOM   5682 C  CB   . LYS A 1 382 ? 158.116 186.031 136.851 1.00 104.38 ? 393 LYS A CB   1 
ATOM   5683 H  H    . LYS A 1 382 ? 159.279 186.636 138.918 1.00 108.13 ? 393 LYS A H    1 
ATOM   5684 H  HA   . LYS A 1 382 ? 157.561 187.929 137.380 1.00 107.26 ? 393 LYS A HA   1 
ATOM   5685 N  N    . ALA A 1 383 ? 156.346 186.055 139.632 1.00 106.09 ? 394 ALA A N    1 
ATOM   5686 C  CA   . ALA A 1 383 ? 155.101 185.635 140.268 1.00 103.67 ? 394 ALA A CA   1 
ATOM   5687 C  C    . ALA A 1 383 ? 154.265 186.831 140.702 1.00 100.62 ? 394 ALA A C    1 
ATOM   5688 O  O    . ALA A 1 383 ? 153.037 186.812 140.579 1.00 100.30 ? 394 ALA A O    1 
ATOM   5689 C  CB   . ALA A 1 383 ? 155.404 184.738 141.468 1.00 103.76 ? 394 ALA A CB   1 
ATOM   5690 H  H    . ALA A 1 383 ? 157.056 185.841 140.067 1.00 103.46 ? 394 ALA A H    1 
ATOM   5691 H  HA   . ALA A 1 383 ? 154.579 185.121 139.633 1.00 102.34 ? 394 ALA A HA   1 
ATOM   5692 H  HB1  . ALA A 1 383 ? 154.572 184.380 141.814 1.00 102.08 ? 394 ALA A HB1  1 
ATOM   5693 H  HB2  . ALA A 1 383 ? 155.985 184.016 141.185 1.00 101.81 ? 394 ALA A HB2  1 
ATOM   5694 H  HB3  . ALA A 1 383 ? 155.849 185.266 142.149 1.00 102.41 ? 394 ALA A HB3  1 
ATOM   5695 N  N    . THR A 1 384 ? 154.906 187.866 141.242 1.00 101.69 ? 395 THR A N    1 
ATOM   5696 C  CA   . THR A 1 384 ? 154.153 189.046 141.669 1.00 103.22 ? 395 THR A CA   1 
ATOM   5697 C  C    . THR A 1 384 ? 153.443 189.700 140.485 1.00 102.96 ? 395 THR A C    1 
ATOM   5698 O  O    . THR A 1 384 ? 152.240 189.998 140.543 1.00 98.49  ? 395 THR A O    1 
ATOM   5699 C  CB   . THR A 1 384 ? 155.082 190.047 142.357 1.00 104.56 ? 395 THR A CB   1 
ATOM   5700 O  OG1  . THR A 1 384 ? 156.093 190.479 141.437 1.00 108.44 ? 395 THR A OG1  1 
ATOM   5701 C  CG2  . THR A 1 384 ? 155.736 189.423 143.583 1.00 103.34 ? 395 THR A CG2  1 
ATOM   5702 H  H    . THR A 1 384 ? 155.755 187.912 141.370 1.00 103.77 ? 395 THR A H    1 
ATOM   5703 H  HA   . THR A 1 384 ? 153.478 188.774 142.310 1.00 103.13 ? 395 THR A HA   1 
ATOM   5704 H  HB   . THR A 1 384 ? 154.565 190.815 142.647 1.00 103.39 ? 395 THR A HB   1 
ATOM   5705 H  HG1  . THR A 1 384 ? 156.546 189.821 141.179 1.00 104.71 ? 395 THR A HG1  1 
ATOM   5706 H  HG21 . THR A 1 384 ? 156.282 190.083 144.039 1.00 103.82 ? 395 THR A HG21 1 
ATOM   5707 H  HG22 . THR A 1 384 ? 155.054 189.102 144.194 1.00 103.18 ? 395 THR A HG22 1 
ATOM   5708 H  HG23 . THR A 1 384 ? 156.297 188.679 143.320 1.00 103.97 ? 395 THR A HG23 1 
ATOM   5709 N  N    . ILE A 1 385 ? 154.176 189.927 139.393 1.00 98.08  ? 396 ILE A N    1 
ATOM   5710 C  CA   . ILE A 1 385 ? 153.563 190.537 138.220 1.00 95.66  ? 396 ILE A CA   1 
ATOM   5711 C  C    . ILE A 1 385 ? 152.542 189.596 137.599 1.00 94.36  ? 396 ILE A C    1 
ATOM   5712 O  O    . ILE A 1 385 ? 151.559 190.048 137.008 1.00 93.81  ? 396 ILE A O    1 
ATOM   5713 C  CB   . ILE A 1 385 ? 154.642 190.961 137.205 1.00 96.64  ? 396 ILE A CB   1 
ATOM   5714 C  CG1  . ILE A 1 385 ? 154.020 191.824 136.104 1.00 97.85  ? 396 ILE A CG1  1 
ATOM   5715 C  CG2  . ILE A 1 385 ? 155.339 189.745 136.615 1.00 96.22  ? 396 ILE A CG2  1 
ATOM   5716 C  CD1  . ILE A 1 385 ? 155.036 192.549 135.249 1.00 97.15  ? 396 ILE A CD1  1 
ATOM   5717 H  H    . ILE A 1 385 ? 155.011 189.741 139.310 1.00 97.45  ? 396 ILE A H    1 
ATOM   5718 H  HA   . ILE A 1 385 ? 153.092 191.338 138.499 1.00 96.70  ? 396 ILE A HA   1 
ATOM   5719 H  HB   . ILE A 1 385 ? 155.305 191.494 137.671 1.00 96.85  ? 396 ILE A HB   1 
ATOM   5720 H  HG12 . ILE A 1 385 ? 153.495 191.254 135.521 1.00 96.59  ? 396 ILE A HG12 1 
ATOM   5721 H  HG13 . ILE A 1 385 ? 153.449 192.491 136.515 1.00 96.58  ? 396 ILE A HG13 1 
ATOM   5722 H  HG21 . ILE A 1 385 ? 156.042 190.044 136.017 1.00 96.63  ? 396 ILE A HG21 1 
ATOM   5723 H  HG22 . ILE A 1 385 ? 155.723 189.228 137.338 1.00 96.79  ? 396 ILE A HG22 1 
ATOM   5724 H  HG23 . ILE A 1 385 ? 154.696 189.209 136.124 1.00 96.95  ? 396 ILE A HG23 1 
ATOM   5725 H  HD11 . ILE A 1 385 ? 154.568 193.101 134.604 1.00 96.28  ? 396 ILE A HD11 1 
ATOM   5726 H  HD12 . ILE A 1 385 ? 155.590 193.104 135.821 1.00 96.65  ? 396 ILE A HD12 1 
ATOM   5727 H  HD13 . ILE A 1 385 ? 155.586 191.896 134.788 1.00 96.37  ? 396 ILE A HD13 1 
ATOM   5728 N  N    . MET A 1 386 ? 152.743 188.283 137.721 1.00 89.15  ? 397 MET A N    1 
ATOM   5729 C  CA   . MET A 1 386 ? 151.747 187.336 137.235 1.00 87.00  ? 397 MET A CA   1 
ATOM   5730 C  C    . MET A 1 386 ? 150.465 187.428 138.049 1.00 83.68  ? 397 MET A C    1 
ATOM   5731 O  O    . MET A 1 386 ? 149.367 187.310 137.501 1.00 86.71  ? 397 MET A O    1 
ATOM   5732 C  CB   . MET A 1 386 ? 152.307 185.915 137.279 1.00 86.31  ? 397 MET A CB   1 
ATOM   5733 H  H    . MET A 1 386 ? 153.438 187.921 138.078 1.00 89.12  ? 397 MET A H    1 
ATOM   5734 H  HA   . MET A 1 386 ? 151.543 187.546 136.310 1.00 87.71  ? 397 MET A HA   1 
ATOM   5735 N  N    . ALA A 1 387 ? 150.585 187.623 139.362 1.00 75.95  ? 398 ALA A N    1 
ATOM   5736 C  CA   . ALA A 1 387 ? 149.401 187.819 140.190 1.00 79.43  ? 398 ALA A CA   1 
ATOM   5737 C  C    . ALA A 1 387 ? 148.669 189.095 139.798 1.00 85.22  ? 398 ALA A C    1 
ATOM   5738 O  O    . ALA A 1 387 ? 147.435 189.116 139.716 1.00 86.81  ? 398 ALA A O    1 
ATOM   5739 C  CB   . ALA A 1 387 ? 149.793 187.854 141.667 1.00 79.18  ? 398 ALA A CB   1 
ATOM   5740 H  H    . ALA A 1 387 ? 151.330 187.646 139.791 1.00 82.59  ? 398 ALA A H    1 
ATOM   5741 H  HA   . ALA A 1 387 ? 148.795 187.073 140.058 1.00 81.91  ? 398 ALA A HA   1 
ATOM   5742 H  HB1  . ALA A 1 387 ? 148.995 187.986 142.202 1.00 81.54  ? 398 ALA A HB1  1 
ATOM   5743 H  HB2  . ALA A 1 387 ? 150.213 187.012 141.901 1.00 82.12  ? 398 ALA A HB2  1 
ATOM   5744 H  HB3  . ALA A 1 387 ? 150.413 188.585 141.812 1.00 82.28  ? 398 ALA A HB3  1 
ATOM   5745 N  N    . PHE A 1 388 ? 149.416 190.173 139.548 1.00 92.93  ? 399 PHE A N    1 
ATOM   5746 C  CA   . PHE A 1 388 ? 148.778 191.408 139.094 1.00 90.88  ? 399 PHE A CA   1 
ATOM   5747 C  C    . PHE A 1 388 ? 148.095 191.210 137.743 1.00 89.41  ? 399 PHE A C    1 
ATOM   5748 O  O    . PHE A 1 388 ? 146.979 191.702 137.516 1.00 90.10  ? 399 PHE A O    1 
ATOM   5749 C  CB   . PHE A 1 388 ? 149.811 192.532 139.018 1.00 92.73  ? 399 PHE A CB   1 
ATOM   5750 C  CG   . PHE A 1 388 ? 149.294 193.789 138.380 1.00 94.66  ? 399 PHE A CG   1 
ATOM   5751 C  CD1  . PHE A 1 388 ? 148.590 194.720 139.123 1.00 92.02  ? 399 PHE A CD1  1 
ATOM   5752 C  CD2  . PHE A 1 388 ? 149.521 194.045 137.038 1.00 97.53  ? 399 PHE A CD2  1 
ATOM   5753 C  CE1  . PHE A 1 388 ? 148.115 195.877 138.540 1.00 94.32  ? 399 PHE A CE1  1 
ATOM   5754 C  CE2  . PHE A 1 388 ? 149.049 195.202 136.449 1.00 97.74  ? 399 PHE A CE2  1 
ATOM   5755 C  CZ   . PHE A 1 388 ? 148.346 196.119 137.202 1.00 97.05  ? 399 PHE A CZ   1 
ATOM   5756 H  H    . PHE A 1 388 ? 150.271 190.215 139.631 1.00 92.61  ? 399 PHE A H    1 
ATOM   5757 H  HA   . PHE A 1 388 ? 148.100 191.668 139.738 1.00 92.48  ? 399 PHE A HA   1 
ATOM   5758 H  HB2  . PHE A 1 388 ? 150.098 192.753 139.918 1.00 93.31  ? 399 PHE A HB2  1 
ATOM   5759 H  HB3  . PHE A 1 388 ? 150.569 192.225 138.497 1.00 93.18  ? 399 PHE A HB3  1 
ATOM   5760 H  HD1  . PHE A 1 388 ? 148.430 194.562 140.026 1.00 92.41  ? 399 PHE A HD1  1 
ATOM   5761 H  HD2  . PHE A 1 388 ? 149.995 193.430 136.526 1.00 93.77  ? 399 PHE A HD2  1 
ATOM   5762 H  HE1  . PHE A 1 388 ? 147.641 196.494 139.049 1.00 93.31  ? 399 PHE A HE1  1 
ATOM   5763 H  HE2  . PHE A 1 388 ? 149.206 195.363 135.547 1.00 93.46  ? 399 PHE A HE2  1 
ATOM   5764 H  HZ   . PHE A 1 388 ? 148.027 196.899 136.808 1.00 93.70  ? 399 PHE A HZ   1 
ATOM   5765 N  N    . ASP A 1 389 ? 148.755 190.493 136.830 1.00 83.18  ? 400 ASP A N    1 
ATOM   5766 C  CA   . ASP A 1 389 ? 148.167 190.209 135.527 1.00 82.82  ? 400 ASP A CA   1 
ATOM   5767 C  C    . ASP A 1 389 ? 146.903 189.375 135.673 1.00 79.06  ? 400 ASP A C    1 
ATOM   5768 O  O    . ASP A 1 389 ? 145.919 189.595 134.961 1.00 82.13  ? 400 ASP A O    1 
ATOM   5769 C  CB   . ASP A 1 389 ? 149.183 189.490 134.641 1.00 84.40  ? 400 ASP A CB   1 
ATOM   5770 C  CG   . ASP A 1 389 ? 148.578 189.005 133.339 1.00 84.72  ? 400 ASP A CG   1 
ATOM   5771 O  OD1  . ASP A 1 389 ? 148.083 189.847 132.561 1.00 83.81  ? 400 ASP A OD1  1 
ATOM   5772 O  OD2  . ASP A 1 389 ? 148.598 187.780 133.093 1.00 86.06  ? 400 ASP A OD2  1 
ATOM   5773 H  H    . ASP A 1 389 ? 149.541 190.163 136.944 1.00 84.62  ? 400 ASP A H    1 
ATOM   5774 H  HA   . ASP A 1 389 ? 147.947 191.044 135.092 1.00 84.30  ? 400 ASP A HA   1 
ATOM   5775 H  HB2  . ASP A 1 389 ? 149.905 190.101 134.428 1.00 84.37  ? 400 ASP A HB2  1 
ATOM   5776 H  HB3  . ASP A 1 389 ? 149.529 188.719 135.117 1.00 84.30  ? 400 ASP A HB3  1 
ATOM   5777 N  N    . ALA A 1 390 ? 146.920 188.401 136.582 1.00 73.82  ? 401 ALA A N    1 
ATOM   5778 C  CA   . ALA A 1 390 ? 145.729 187.605 136.841 1.00 73.31  ? 401 ALA A CA   1 
ATOM   5779 C  C    . ALA A 1 390 ? 144.602 188.473 137.378 1.00 73.22  ? 401 ALA A C    1 
ATOM   5780 O  O    . ALA A 1 390 ? 143.442 188.307 136.987 1.00 75.73  ? 401 ALA A O    1 
ATOM   5781 C  CB   . ALA A 1 390 ? 146.055 186.477 137.820 1.00 76.26  ? 401 ALA A CB   1 
ATOM   5782 H  H    . ALA A 1 390 ? 147.603 188.185 137.057 1.00 76.80  ? 401 ALA A H    1 
ATOM   5783 H  HA   . ALA A 1 390 ? 145.432 187.201 136.012 1.00 75.39  ? 401 ALA A HA   1 
ATOM   5784 H  HB1  . ALA A 1 390 ? 145.252 185.957 137.980 1.00 75.73  ? 401 ALA A HB1  1 
ATOM   5785 H  HB2  . ALA A 1 390 ? 146.742 185.913 137.432 1.00 76.65  ? 401 ALA A HB2  1 
ATOM   5786 H  HB3  . ALA A 1 390 ? 146.373 186.861 138.652 1.00 75.92  ? 401 ALA A HB3  1 
ATOM   5787 N  N    . LEU A 1 391 ? 144.921 189.408 138.276 1.00 77.43  ? 402 LEU A N    1 
ATOM   5788 C  CA   . LEU A 1 391 ? 143.889 190.292 138.807 1.00 80.89  ? 402 LEU A CA   1 
ATOM   5789 C  C    . LEU A 1 391 ? 143.258 191.116 137.692 1.00 79.91  ? 402 LEU A C    1 
ATOM   5790 O  O    . LEU A 1 391 ? 142.028 191.205 137.586 1.00 82.31  ? 402 LEU A O    1 
ATOM   5791 C  CB   . LEU A 1 391 ? 144.474 191.206 139.888 1.00 85.74  ? 402 LEU A CB   1 
ATOM   5792 C  CG   . LEU A 1 391 ? 143.483 192.097 140.650 1.00 85.14  ? 402 LEU A CG   1 
ATOM   5793 C  CD1  . LEU A 1 391 ? 142.241 191.329 141.077 1.00 84.71  ? 402 LEU A CD1  1 
ATOM   5794 C  CD2  . LEU A 1 391 ? 144.153 192.731 141.863 1.00 83.51  ? 402 LEU A CD2  1 
ATOM   5795 H  H    . LEU A 1 391 ? 145.712 189.551 138.583 1.00 81.87  ? 402 LEU A H    1 
ATOM   5796 H  HA   . LEU A 1 391 ? 143.194 189.748 139.208 1.00 82.05  ? 402 LEU A HA   1 
ATOM   5797 H  HB2  . LEU A 1 391 ? 144.930 190.659 140.545 1.00 83.32  ? 402 LEU A HB2  1 
ATOM   5798 H  HB3  . LEU A 1 391 ? 145.118 191.797 139.466 1.00 82.69  ? 402 LEU A HB3  1 
ATOM   5799 H  HG   . LEU A 1 391 ? 143.192 192.814 140.067 1.00 82.39  ? 402 LEU A HG   1 
ATOM   5800 H  HD11 . LEU A 1 391 ? 141.746 191.863 141.718 1.00 82.77  ? 402 LEU A HD11 1 
ATOM   5801 H  HD12 . LEU A 1 391 ? 141.692 191.158 140.296 1.00 82.62  ? 402 LEU A HD12 1 
ATOM   5802 H  HD13 . LEU A 1 391 ? 142.510 190.492 141.483 1.00 83.01  ? 402 LEU A HD13 1 
ATOM   5803 H  HD21 . LEU A 1 391 ? 143.546 193.376 142.258 1.00 81.91  ? 402 LEU A HD21 1 
ATOM   5804 H  HD22 . LEU A 1 391 ? 144.362 192.036 142.507 1.00 82.33  ? 402 LEU A HD22 1 
ATOM   5805 H  HD23 . LEU A 1 391 ? 144.967 193.174 141.577 1.00 82.98  ? 402 LEU A HD23 1 
ATOM   5806 N  N    . VAL A 1 392 ? 144.086 191.718 136.836 1.00 84.37  ? 403 VAL A N    1 
ATOM   5807 C  CA   . VAL A 1 392 ? 143.538 192.541 135.757 1.00 86.63  ? 403 VAL A CA   1 
ATOM   5808 C  C    . VAL A 1 392 ? 142.730 191.681 134.789 1.00 83.82  ? 403 VAL A C    1 
ATOM   5809 O  O    . VAL A 1 392 ? 141.627 192.055 134.377 1.00 85.86  ? 403 VAL A O    1 
ATOM   5810 C  CB   . VAL A 1 392 ? 144.651 193.325 135.036 1.00 87.37  ? 403 VAL A CB   1 
ATOM   5811 C  CG1  . VAL A 1 392 ? 145.263 194.353 135.977 1.00 89.28  ? 403 VAL A CG1  1 
ATOM   5812 C  CG2  . VAL A 1 392 ? 145.712 192.401 134.495 1.00 87.84  ? 403 VAL A CG2  1 
ATOM   5813 H  H    . VAL A 1 392 ? 144.943 191.668 136.860 1.00 86.04  ? 403 VAL A H    1 
ATOM   5814 H  HA   . VAL A 1 392 ? 142.932 193.190 136.147 1.00 86.86  ? 403 VAL A HA   1 
ATOM   5815 H  HB   . VAL A 1 392 ? 144.262 193.803 134.287 1.00 86.58  ? 403 VAL A HB   1 
ATOM   5816 H  HG11 . VAL A 1 392 ? 146.068 194.712 135.572 1.00 87.60  ? 403 VAL A HG11 1 
ATOM   5817 H  HG12 . VAL A 1 392 ? 144.621 195.065 136.123 1.00 87.05  ? 403 VAL A HG12 1 
ATOM   5818 H  HG13 . VAL A 1 392 ? 145.481 193.923 136.818 1.00 87.05  ? 403 VAL A HG13 1 
ATOM   5819 H  HG21 . VAL A 1 392 ? 146.403 192.932 134.069 1.00 86.76  ? 403 VAL A HG21 1 
ATOM   5820 H  HG22 . VAL A 1 392 ? 146.085 191.912 135.238 1.00 86.78  ? 403 VAL A HG22 1 
ATOM   5821 H  HG23 . VAL A 1 392 ? 145.318 191.793 133.852 1.00 86.48  ? 403 VAL A HG23 1 
ATOM   5822 N  N    . THR A 1 393 ? 143.250 190.507 134.424 1.00 91.86  ? 404 THR A N    1 
ATOM   5823 C  CA   . THR A 1 393 ? 142.514 189.642 133.507 1.00 94.15  ? 404 THR A CA   1 
ATOM   5824 C  C    . THR A 1 393 ? 141.170 189.241 134.099 1.00 92.94  ? 404 THR A C    1 
ATOM   5825 O  O    . THR A 1 393 ? 140.159 189.185 133.389 1.00 94.88  ? 404 THR A O    1 
ATOM   5826 C  CB   . THR A 1 393 ? 143.347 188.406 133.162 1.00 97.81  ? 404 THR A CB   1 
ATOM   5827 O  OG1  . THR A 1 393 ? 143.878 187.829 134.361 1.00 97.69  ? 404 THR A OG1  1 
ATOM   5828 C  CG2  . THR A 1 393 ? 144.492 188.781 132.227 1.00 96.31  ? 404 THR A CG2  1 
ATOM   5829 H  H    . THR A 1 393 ? 144.006 190.193 134.691 1.00 93.21  ? 404 THR A H    1 
ATOM   5830 H  HA   . THR A 1 393 ? 142.343 190.126 132.685 1.00 93.72  ? 404 THR A HA   1 
ATOM   5831 H  HB   . THR A 1 393 ? 142.786 187.755 132.712 1.00 94.26  ? 404 THR A HB   1 
ATOM   5832 H  HG1  . THR A 1 393 ? 143.258 187.660 134.903 1.00 93.39  ? 404 THR A HG1  1 
ATOM   5833 H  HG21 . THR A 1 393 ? 144.138 189.118 131.390 1.00 93.80  ? 404 THR A HG21 1 
ATOM   5834 H  HG22 . THR A 1 393 ? 145.040 189.469 132.635 1.00 93.75  ? 404 THR A HG22 1 
ATOM   5835 H  HG23 . THR A 1 393 ? 145.043 188.004 132.046 1.00 93.88  ? 404 THR A HG23 1 
ATOM   5836 N  N    . PHE A 1 394 ? 141.138 188.968 135.404 1.00 73.85  ? 405 PHE A N    1 
ATOM   5837 C  CA   . PHE A 1 394 ? 139.867 188.792 136.094 1.00 74.40  ? 405 PHE A CA   1 
ATOM   5838 C  C    . PHE A 1 394 ? 139.001 190.037 135.956 1.00 68.82  ? 405 PHE A C    1 
ATOM   5839 O  O    . PHE A 1 394 ? 137.768 189.947 135.915 1.00 68.93  ? 405 PHE A O    1 
ATOM   5840 C  CB   . PHE A 1 394 ? 140.130 188.467 137.565 1.00 78.40  ? 405 PHE A CB   1 
ATOM   5841 C  CG   . PHE A 1 394 ? 138.997 188.819 138.475 1.00 75.47  ? 405 PHE A CG   1 
ATOM   5842 C  CD1  . PHE A 1 394 ? 137.996 187.906 138.733 1.00 71.86  ? 405 PHE A CD1  1 
ATOM   5843 C  CD2  . PHE A 1 394 ? 138.931 190.065 139.069 1.00 78.15  ? 405 PHE A CD2  1 
ATOM   5844 C  CE1  . PHE A 1 394 ? 136.953 188.222 139.568 1.00 73.58  ? 405 PHE A CE1  1 
ATOM   5845 C  CE2  . PHE A 1 394 ? 137.886 190.392 139.903 1.00 74.24  ? 405 PHE A CE2  1 
ATOM   5846 C  CZ   . PHE A 1 394 ? 136.895 189.469 140.154 1.00 73.26  ? 405 PHE A CZ   1 
ATOM   5847 H  H    . PHE A 1 394 ? 141.831 188.878 135.906 1.00 75.45  ? 405 PHE A H    1 
ATOM   5848 H  HA   . PHE A 1 394 ? 139.388 188.044 135.702 1.00 75.16  ? 405 PHE A HA   1 
ATOM   5849 H  HB2  . PHE A 1 394 ? 140.280 187.513 137.649 1.00 75.44  ? 405 PHE A HB2  1 
ATOM   5850 H  HB3  . PHE A 1 394 ? 140.917 188.947 137.865 1.00 76.13  ? 405 PHE A HB3  1 
ATOM   5851 H  HD1  . PHE A 1 394 ? 138.034 187.065 138.341 1.00 74.10  ? 405 PHE A HD1  1 
ATOM   5852 H  HD2  . PHE A 1 394 ? 139.597 190.691 138.899 1.00 75.54  ? 405 PHE A HD2  1 
ATOM   5853 H  HE1  . PHE A 1 394 ? 136.287 187.595 139.734 1.00 74.50  ? 405 PHE A HE1  1 
ATOM   5854 H  HE2  . PHE A 1 394 ? 137.852 191.234 140.296 1.00 74.46  ? 405 PHE A HE2  1 
ATOM   5855 H  HZ   . PHE A 1 394 ? 136.189 189.686 140.718 1.00 74.27  ? 405 PHE A HZ   1 
ATOM   5856 N  N    . CYS A 1 395 ? 139.631 191.213 135.911 1.00 68.11  ? 406 CYS A N    1 
ATOM   5857 C  CA   . CYS A 1 395 ? 138.876 192.456 135.784 1.00 72.54  ? 406 CYS A CA   1 
ATOM   5858 C  C    . CYS A 1 395 ? 138.175 192.558 134.428 1.00 77.29  ? 406 CYS A C    1 
ATOM   5859 O  O    . CYS A 1 395 ? 136.968 192.819 134.365 1.00 85.70  ? 406 CYS A O    1 
ATOM   5860 C  CB   . CYS A 1 395 ? 139.806 193.651 136.010 1.00 76.85  ? 406 CYS A CB   1 
ATOM   5861 S  SG   . CYS A 1 395 ? 138.955 195.215 136.287 1.00 72.85  ? 406 CYS A SG   1 
ATOM   5862 H  H    . CYS A 1 395 ? 140.482 191.316 135.952 1.00 76.61  ? 406 CYS A H    1 
ATOM   5863 H  HA   . CYS A 1 395 ? 138.193 192.471 136.473 1.00 76.33  ? 406 CYS A HA   1 
ATOM   5864 H  HB2  . CYS A 1 395 ? 140.358 193.471 136.790 1.00 77.05  ? 406 CYS A HB2  1 
ATOM   5865 H  HB3  . CYS A 1 395 ? 140.372 193.763 135.232 1.00 78.06  ? 406 CYS A HB3  1 
ATOM   5866 H  HG   . CYS A 1 395 ? 139.682 196.019 136.801 1.00 76.94  ? 406 CYS A HG   1 
ATOM   5867 N  N    . GLU A 1 396 ? 138.917 192.378 133.331 1.00 75.56  ? 407 GLU A N    1 
ATOM   5868 C  CA   . GLU A 1 396 ? 138.348 192.464 131.980 1.00 77.26  ? 407 GLU A CA   1 
ATOM   5869 C  C    . GLU A 1 396 ? 138.077 191.068 131.419 1.00 75.42  ? 407 GLU A C    1 
ATOM   5870 O  O    . GLU A 1 396 ? 138.696 190.618 130.453 1.00 75.44  ? 407 GLU A O    1 
ATOM   5871 C  CB   . GLU A 1 396 ? 139.277 193.242 131.054 1.00 77.81  ? 407 GLU A CB   1 
ATOM   5872 C  CG   . GLU A 1 396 ? 139.414 194.696 131.404 1.00 78.06  ? 407 GLU A CG   1 
ATOM   5873 C  CD   . GLU A 1 396 ? 140.423 194.909 132.502 1.00 80.44  ? 407 GLU A CD   1 
ATOM   5874 O  OE1  . GLU A 1 396 ? 141.046 193.919 132.925 1.00 80.78  ? 407 GLU A OE1  1 
ATOM   5875 O  OE2  . GLU A 1 396 ? 140.584 196.054 132.962 1.00 84.60  ? 407 GLU A OE2  1 
ATOM   5876 H  H    . GLU A 1 396 ? 139.762 192.215 133.342 1.00 78.66  ? 407 GLU A H    1 
ATOM   5877 H  HA   . GLU A 1 396 ? 137.506 192.938 132.023 1.00 78.56  ? 407 GLU A HA   1 
ATOM   5878 H  HB2  . GLU A 1 396 ? 140.159 192.841 131.069 1.00 78.75  ? 407 GLU A HB2  1 
ATOM   5879 H  HB3  . GLU A 1 396 ? 138.917 193.197 130.155 1.00 78.49  ? 407 GLU A HB3  1 
ATOM   5880 H  HG2  . GLU A 1 396 ? 139.730 195.167 130.616 1.00 78.71  ? 407 GLU A HG2  1 
ATOM   5881 H  HG3  . GLU A 1 396 ? 138.551 195.043 131.684 1.00 78.26  ? 407 GLU A HG3  1 
ATOM   5882 N  N    . GLU A 1 397 ? 137.114 190.388 132.033 1.00 64.89  ? 408 GLU A N    1 
ATOM   5883 C  CA   . GLU A 1 397 ? 136.703 189.062 131.586 1.00 63.78  ? 408 GLU A CA   1 
ATOM   5884 C  C    . GLU A 1 397 ? 135.186 189.024 131.524 1.00 61.81  ? 408 GLU A C    1 
ATOM   5885 O  O    . GLU A 1 397 ? 134.518 189.166 132.553 1.00 68.93  ? 408 GLU A O    1 
ATOM   5886 C  CB   . GLU A 1 397 ? 137.231 187.973 132.525 1.00 63.66  ? 408 GLU A CB   1 
ATOM   5887 H  H    . GLU A 1 397 ? 136.685 190.672 132.719 1.00 66.86  ? 408 GLU A H    1 
ATOM   5888 H  HA   . GLU A 1 397 ? 137.048 188.890 130.695 1.00 65.55  ? 408 GLU A HA   1 
ATOM   5889 N  N    . LEU A 1 398 ? 134.646 188.821 130.322 1.00 67.87  ? 409 LEU A N    1 
ATOM   5890 C  CA   . LEU A 1 398 ? 133.202 188.707 130.127 1.00 73.33  ? 409 LEU A CA   1 
ATOM   5891 C  C    . LEU A 1 398 ? 132.737 187.306 130.530 1.00 73.73  ? 409 LEU A C    1 
ATOM   5892 O  O    . LEU A 1 398 ? 132.131 186.556 129.765 1.00 79.27  ? 409 LEU A O    1 
ATOM   5893 C  CB   . LEU A 1 398 ? 132.837 189.046 128.684 1.00 83.25  ? 409 LEU A CB   1 
ATOM   5894 C  CG   . LEU A 1 398 ? 133.178 188.071 127.545 1.00 82.71  ? 409 LEU A CG   1 
ATOM   5895 C  CD1  . LEU A 1 398 ? 132.407 188.429 126.283 1.00 75.60  ? 409 LEU A CD1  1 
ATOM   5896 C  CD2  . LEU A 1 398 ? 134.675 188.052 127.257 1.00 78.07  ? 409 LEU A CD2  1 
ATOM   5897 H  H    . LEU A 1 398 ? 135.101 188.744 129.599 1.00 75.83  ? 409 LEU A H    1 
ATOM   5898 H  HA   . LEU A 1 398 ? 132.753 189.344 130.704 1.00 75.74  ? 409 LEU A HA   1 
ATOM   5899 H  HB2  . LEU A 1 398 ? 131.877 189.187 128.652 1.00 77.41  ? 409 LEU A HB2  1 
ATOM   5900 H  HB3  . LEU A 1 398 ? 133.278 189.883 128.468 1.00 77.32  ? 409 LEU A HB3  1 
ATOM   5901 H  HG   . LEU A 1 398 ? 132.920 187.173 127.792 1.00 77.75  ? 409 LEU A HG   1 
ATOM   5902 H  HD11 . LEU A 1 398 ? 132.436 187.675 125.674 1.00 76.26  ? 409 LEU A HD11 1 
ATOM   5903 H  HD12 . LEU A 1 398 ? 131.488 188.629 126.518 1.00 76.18  ? 409 LEU A HD12 1 
ATOM   5904 H  HD13 . LEU A 1 398 ? 132.820 189.203 125.871 1.00 76.50  ? 409 LEU A HD13 1 
ATOM   5905 H  HD21 . LEU A 1 398 ? 134.823 187.655 126.385 1.00 76.49  ? 409 LEU A HD21 1 
ATOM   5906 H  HD22 . LEU A 1 398 ? 135.012 188.963 127.265 1.00 77.03  ? 409 LEU A HD22 1 
ATOM   5907 H  HD23 . LEU A 1 398 ? 135.124 187.528 127.939 1.00 76.83  ? 409 LEU A HD23 1 
ATOM   5908 N  N    . GLY A 1 399 ? 133.036 186.964 131.782 1.00 58.37  ? 410 GLY A N    1 
ATOM   5909 C  CA   . GLY A 1 399 ? 132.723 185.653 132.307 1.00 62.29  ? 410 GLY A CA   1 
ATOM   5910 C  C    . GLY A 1 399 ? 132.453 185.738 133.792 1.00 60.31  ? 410 GLY A C    1 
ATOM   5911 O  O    . GLY A 1 399 ? 132.663 186.775 134.427 1.00 63.07  ? 410 GLY A O    1 
ATOM   5912 H  H    . GLY A 1 399 ? 133.419 187.485 132.349 1.00 62.07  ? 410 GLY A H    1 
ATOM   5913 H  HA2  . GLY A 1 399 ? 131.939 185.299 131.863 1.00 62.49  ? 410 GLY A HA2  1 
ATOM   5914 H  HA3  . GLY A 1 399 ? 133.467 185.051 132.155 1.00 63.17  ? 410 GLY A HA3  1 
ATOM   5915 N  N    . CYS A 1 400 ? 131.974 184.627 134.342 1.00 62.00  ? 411 CYS A N    1 
ATOM   5916 C  CA   . CYS A 1 400 ? 131.686 184.564 135.768 1.00 64.51  ? 411 CYS A CA   1 
ATOM   5917 C  C    . CYS A 1 400 ? 132.925 184.930 136.568 1.00 66.73  ? 411 CYS A C    1 
ATOM   5918 O  O    . CYS A 1 400 ? 133.969 184.284 136.447 1.00 65.37  ? 411 CYS A O    1 
ATOM   5919 C  CB   . CYS A 1 400 ? 131.202 183.164 136.146 1.00 64.91  ? 411 CYS A CB   1 
ATOM   5920 S  SG   . CYS A 1 400 ? 131.150 182.859 137.929 1.00 67.90  ? 411 CYS A SG   1 
ATOM   5921 H  H    . CYS A 1 400 ? 131.812 183.899 133.914 1.00 64.49  ? 411 CYS A H    1 
ATOM   5922 H  HA   . CYS A 1 400 ? 130.985 185.198 135.984 1.00 64.86  ? 411 CYS A HA   1 
ATOM   5923 H  HB2  . CYS A 1 400 ? 130.308 183.039 135.793 1.00 65.06  ? 411 CYS A HB2  1 
ATOM   5924 H  HB3  . CYS A 1 400 ? 131.803 182.511 135.755 1.00 65.45  ? 411 CYS A HB3  1 
ATOM   5925 N  N    . ARG A 1 401 ? 132.808 185.980 137.381 1.00 66.73  ? 412 ARG A N    1 
ATOM   5926 C  CA   . ARG A 1 401 ? 133.950 186.424 138.171 1.00 64.75  ? 412 ARG A CA   1 
ATOM   5927 C  C    . ARG A 1 401 ? 134.331 185.395 139.227 1.00 67.82  ? 412 ARG A C    1 
ATOM   5928 O  O    . ARG A 1 401 ? 135.521 185.214 139.513 1.00 69.72  ? 412 ARG A O    1 
ATOM   5929 C  CB   . ARG A 1 401 ? 133.638 187.778 138.804 1.00 65.89  ? 412 ARG A CB   1 
ATOM   5930 C  CG   . ARG A 1 401 ? 133.724 188.920 137.803 1.00 67.69  ? 412 ARG A CG   1 
ATOM   5931 C  CD   . ARG A 1 401 ? 133.203 190.234 138.376 1.00 72.93  ? 412 ARG A CD   1 
ATOM   5932 N  NE   . ARG A 1 401 ? 133.035 191.287 137.377 1.00 73.43  ? 412 ARG A NE   1 
ATOM   5933 C  CZ   . ARG A 1 401 ? 133.940 191.665 136.481 1.00 71.80  ? 412 ARG A CZ   1 
ATOM   5934 N  NH1  . ARG A 1 401 ? 135.181 191.206 136.503 1.00 73.35  ? 412 ARG A NH1  1 
ATOM   5935 N  NH2  . ARG A 1 401 ? 133.596 192.551 135.550 1.00 65.15  ? 412 ARG A NH2  1 
ATOM   5936 H  H    . ARG A 1 401 ? 132.092 186.443 137.490 1.00 69.08  ? 412 ARG A H    1 
ATOM   5937 H  HA   . ARG A 1 401 ? 134.712 186.541 137.582 1.00 69.38  ? 412 ARG A HA   1 
ATOM   5938 H  HB2  . ARG A 1 401 ? 132.733 187.759 139.153 1.00 69.89  ? 412 ARG A HB2  1 
ATOM   5939 H  HB3  . ARG A 1 401 ? 134.263 187.953 139.522 1.00 70.03  ? 412 ARG A HB3  1 
ATOM   5940 H  HG2  . ARG A 1 401 ? 134.652 189.022 137.555 1.00 69.82  ? 412 ARG A HG2  1 
ATOM   5941 H  HG3  . ARG A 1 401 ? 133.192 188.699 137.023 1.00 69.36  ? 412 ARG A HG3  1 
ATOM   5942 H  HD2  . ARG A 1 401 ? 132.338 190.075 138.785 1.00 71.03  ? 412 ARG A HD2  1 
ATOM   5943 H  HD3  . ARG A 1 401 ? 133.829 190.555 139.044 1.00 71.19  ? 412 ARG A HD3  1 
ATOM   5944 H  HE   . ARG A 1 401 ? 132.284 191.707 137.375 1.00 70.68  ? 412 ARG A HE   1 
ATOM   5945 H  HH11 . ARG A 1 401 ? 135.430 190.642 137.097 1.00 70.75  ? 412 ARG A HH11 1 
ATOM   5946 H  HH12 . ARG A 1 401 ? 135.745 191.480 135.914 1.00 70.92  ? 412 ARG A HH12 1 
ATOM   5947 H  HH21 . ARG A 1 401 ? 132.795 192.860 135.526 1.00 69.61  ? 412 ARG A HH21 1 
ATOM   5948 H  HH22 . ARG A 1 401 ? 134.176 192.811 134.970 1.00 69.43  ? 412 ARG A HH22 1 
ATOM   5949 N  N    . HIS A 1 402 ? 133.344 184.707 139.807 1.00 65.75  ? 413 HIS A N    1 
ATOM   5950 C  CA   . HIS A 1 402 ? 133.651 183.605 140.710 1.00 64.02  ? 413 HIS A CA   1 
ATOM   5951 C  C    . HIS A 1 402 ? 134.434 182.518 139.984 1.00 64.24  ? 413 HIS A C    1 
ATOM   5952 O  O    . HIS A 1 402 ? 135.352 181.915 140.553 1.00 66.31  ? 413 HIS A O    1 
ATOM   5953 C  CB   . HIS A 1 402 ? 132.362 183.036 141.301 1.00 63.69  ? 413 HIS A CB   1 
ATOM   5954 C  CG   . HIS A 1 402 ? 131.671 183.961 142.254 1.00 66.65  ? 413 HIS A CG   1 
ATOM   5955 N  ND1  . HIS A 1 402 ? 130.666 184.818 141.860 1.00 71.18  ? 413 HIS A ND1  1 
ATOM   5956 C  CD2  . HIS A 1 402 ? 131.829 184.153 143.584 1.00 65.26  ? 413 HIS A CD2  1 
ATOM   5957 C  CE1  . HIS A 1 402 ? 130.241 185.504 142.905 1.00 68.22  ? 413 HIS A CE1  1 
ATOM   5958 N  NE2  . HIS A 1 402 ? 130.929 185.119 143.965 1.00 63.43  ? 413 HIS A NE2  1 
ATOM   5959 H  H    . HIS A 1 402 ? 132.505 184.858 139.694 1.00 67.32  ? 413 HIS A H    1 
ATOM   5960 H  HA   . HIS A 1 402 ? 134.197 183.931 141.441 1.00 67.29  ? 413 HIS A HA   1 
ATOM   5961 H  HB2  . HIS A 1 402 ? 131.744 182.833 140.584 1.00 67.31  ? 413 HIS A HB2  1 
ATOM   5962 H  HB3  . HIS A 1 402 ? 132.576 182.226 141.788 1.00 67.14  ? 413 HIS A HB3  1 
ATOM   5963 H  HD1  . HIS A 1 402 ? 130.366 184.897 141.058 1.00 68.32  ? 413 HIS A HD1  1 
ATOM   5964 H  HD2  . HIS A 1 402 ? 132.436 183.716 144.137 1.00 67.53  ? 413 HIS A HD2  1 
ATOM   5965 H  HE1  . HIS A 1 402 ? 129.570 186.148 142.897 1.00 68.38  ? 413 HIS A HE1  1 
ATOM   5966 N  N    . ALA A 1 403 ? 134.085 182.255 138.722 1.00 59.07  ? 414 ALA A N    1 
ATOM   5967 C  CA   . ALA A 1 403 ? 134.832 181.280 137.936 1.00 61.04  ? 414 ALA A CA   1 
ATOM   5968 C  C    . ALA A 1 403 ? 136.284 181.708 137.764 1.00 64.14  ? 414 ALA A C    1 
ATOM   5969 O  O    . ALA A 1 403 ? 137.197 180.883 137.871 1.00 66.08  ? 414 ALA A O    1 
ATOM   5970 C  CB   . ALA A 1 403 ? 134.167 181.084 136.574 1.00 66.38  ? 414 ALA A CB   1 
ATOM   5971 H  H    . ALA A 1 403 ? 133.428 182.624 138.307 1.00 64.20  ? 414 ALA A H    1 
ATOM   5972 H  HA   . ALA A 1 403 ? 134.826 180.428 138.392 1.00 63.23  ? 414 ALA A HA   1 
ATOM   5973 H  HB1  . ALA A 1 403 ? 134.667 180.421 136.072 1.00 64.36  ? 414 ALA A HB1  1 
ATOM   5974 H  HB2  . ALA A 1 403 ? 133.256 180.779 136.709 1.00 64.20  ? 414 ALA A HB2  1 
ATOM   5975 H  HB3  . ALA A 1 403 ? 134.166 181.928 136.097 1.00 64.60  ? 414 ALA A HB3  1 
ATOM   5976 N  N    . ALA A 1 404 ? 136.517 182.991 137.485 1.00 63.21  ? 415 ALA A N    1 
ATOM   5977 C  CA   . ALA A 1 404 ? 137.886 183.473 137.335 1.00 59.35  ? 415 ALA A CA   1 
ATOM   5978 C  C    . ALA A 1 404 ? 138.655 183.370 138.646 1.00 59.03  ? 415 ALA A C    1 
ATOM   5979 O  O    . ALA A 1 404 ? 139.837 183.001 138.654 1.00 66.20  ? 415 ALA A O    1 
ATOM   5980 C  CB   . ALA A 1 404 ? 137.878 184.913 136.827 1.00 63.43  ? 415 ALA A CB   1 
ATOM   5981 H  H    . ALA A 1 404 ? 135.911 183.591 137.379 1.00 63.68  ? 415 ALA A H    1 
ATOM   5982 H  HA   . ALA A 1 404 ? 138.343 182.926 136.677 1.00 62.77  ? 415 ALA A HA   1 
ATOM   5983 H  HB1  . ALA A 1 404 ? 138.787 185.251 136.817 1.00 63.60  ? 415 ALA A HB1  1 
ATOM   5984 H  HB2  . ALA A 1 404 ? 137.508 184.930 135.930 1.00 64.18  ? 415 ALA A HB2  1 
ATOM   5985 H  HB3  . ALA A 1 404 ? 137.331 185.449 137.421 1.00 63.82  ? 415 ALA A HB3  1 
ATOM   5986 N  N    . ILE A 1 405 ? 138.007 183.697 139.766 1.00 64.20  ? 416 ILE A N    1 
ATOM   5987 C  CA   . ILE A 1 405 ? 138.669 183.565 141.061 1.00 66.94  ? 416 ILE A CA   1 
ATOM   5988 C  C    . ILE A 1 405 ? 139.043 182.110 141.314 1.00 73.30  ? 416 ILE A C    1 
ATOM   5989 O  O    . ILE A 1 405 ? 140.151 181.806 141.775 1.00 80.39  ? 416 ILE A O    1 
ATOM   5990 C  CB   . ILE A 1 405 ? 137.774 184.124 142.183 1.00 67.01  ? 416 ILE A CB   1 
ATOM   5991 C  CG1  . ILE A 1 405 ? 137.538 185.625 141.993 1.00 69.73  ? 416 ILE A CG1  1 
ATOM   5992 C  CG2  . ILE A 1 405 ? 138.405 183.871 143.542 1.00 67.24  ? 416 ILE A CG2  1 
ATOM   5993 C  CD1  . ILE A 1 405 ? 136.157 186.085 142.398 1.00 73.81  ? 416 ILE A CD1  1 
ATOM   5994 H  H    . ILE A 1 405 ? 137.199 183.991 139.802 1.00 69.66  ? 416 ILE A H    1 
ATOM   5995 H  HA   . ILE A 1 405 ? 139.488 184.084 141.048 1.00 70.31  ? 416 ILE A HA   1 
ATOM   5996 H  HB   . ILE A 1 405 ? 136.917 183.670 142.151 1.00 70.21  ? 416 ILE A HB   1 
ATOM   5997 H  HG12 . ILE A 1 405 ? 138.170 186.109 142.544 1.00 70.29  ? 416 ILE A HG12 1 
ATOM   5998 H  HG13 . ILE A 1 405 ? 137.670 185.855 141.060 1.00 70.72  ? 416 ILE A HG13 1 
ATOM   5999 H  HG21 . ILE A 1 405 ? 137.989 184.455 144.195 1.00 69.71  ? 416 ILE A HG21 1 
ATOM   6000 H  HG22 . ILE A 1 405 ? 138.263 182.945 143.790 1.00 70.45  ? 416 ILE A HG22 1 
ATOM   6001 H  HG23 . ILE A 1 405 ? 139.355 184.060 143.489 1.00 70.10  ? 416 ILE A HG23 1 
ATOM   6002 H  HD11 . ILE A 1 405 ? 136.093 187.044 142.266 1.00 71.86  ? 416 ILE A HD11 1 
ATOM   6003 H  HD12 . ILE A 1 405 ? 135.497 185.634 141.851 1.00 71.09  ? 416 ILE A HD12 1 
ATOM   6004 H  HD13 . ILE A 1 405 ? 136.016 185.870 143.332 1.00 71.05  ? 416 ILE A HD13 1 
ATOM   6005 N  N    . ALA A 1 406 ? 138.126 181.188 141.013 1.00 70.39  ? 417 ALA A N    1 
ATOM   6006 C  CA   . ALA A 1 406 ? 138.419 179.771 141.196 1.00 69.06  ? 417 ALA A CA   1 
ATOM   6007 C  C    . ALA A 1 406 ? 139.564 179.326 140.295 1.00 66.90  ? 417 ALA A C    1 
ATOM   6008 O  O    . ALA A 1 406 ? 140.425 178.542 140.713 1.00 73.20  ? 417 ALA A O    1 
ATOM   6009 C  CB   . ALA A 1 406 ? 137.168 178.939 140.925 1.00 74.20  ? 417 ALA A CB   1 
ATOM   6010 H  H    . ALA A 1 406 ? 137.341 181.355 140.706 1.00 69.88  ? 417 ALA A H    1 
ATOM   6011 H  HA   . ALA A 1 406 ? 138.687 179.626 142.115 1.00 70.29  ? 417 ALA A HA   1 
ATOM   6012 H  HB1  . ALA A 1 406 ? 137.381 178.001 141.047 1.00 70.32  ? 417 ALA A HB1  1 
ATOM   6013 H  HB2  . ALA A 1 406 ? 136.475 179.205 141.548 1.00 70.56  ? 417 ALA A HB2  1 
ATOM   6014 H  HB3  . ALA A 1 406 ? 136.875 179.097 140.014 1.00 70.96  ? 417 ALA A HB3  1 
ATOM   6015 N  N    . LYS A 1 407 ? 139.589 179.811 139.053 1.00 57.89  ? 418 LYS A N    1 
ATOM   6016 C  CA   . LYS A 1 407 ? 140.699 179.495 138.161 1.00 60.27  ? 418 LYS A CA   1 
ATOM   6017 C  C    . LYS A 1 407 ? 142.018 179.966 138.751 1.00 56.97  ? 418 LYS A C    1 
ATOM   6018 O  O    . LYS A 1 407 ? 143.017 179.237 138.723 1.00 64.49  ? 418 LYS A O    1 
ATOM   6019 C  CB   . LYS A 1 407 ? 140.475 180.134 136.791 1.00 62.00  ? 418 LYS A CB   1 
ATOM   6020 C  CG   . LYS A 1 407 ? 141.580 179.838 135.788 1.00 58.79  ? 418 LYS A CG   1 
ATOM   6021 C  CD   . LYS A 1 407 ? 141.213 180.313 134.393 1.00 62.26  ? 418 LYS A CD   1 
ATOM   6022 C  CE   . LYS A 1 407 ? 142.233 179.852 133.365 1.00 64.64  ? 418 LYS A CE   1 
ATOM   6023 N  NZ   . LYS A 1 407 ? 143.554 180.511 133.561 1.00 65.43  ? 418 LYS A NZ   1 
ATOM   6024 H  H    . LYS A 1 407 ? 138.985 180.316 138.709 1.00 62.04  ? 418 LYS A H    1 
ATOM   6025 H  HA   . LYS A 1 407 ? 140.748 178.533 138.043 1.00 61.73  ? 418 LYS A HA   1 
ATOM   6026 H  HB2  . LYS A 1 407 ? 139.643 179.800 136.422 1.00 62.02  ? 418 LYS A HB2  1 
ATOM   6027 H  HB3  . LYS A 1 407 ? 140.424 181.096 136.900 1.00 62.27  ? 418 LYS A HB3  1 
ATOM   6028 H  HG2  . LYS A 1 407 ? 142.392 180.295 136.059 1.00 61.09  ? 418 LYS A HG2  1 
ATOM   6029 H  HG3  . LYS A 1 407 ? 141.731 178.881 135.752 1.00 61.59  ? 418 LYS A HG3  1 
ATOM   6030 H  HD2  . LYS A 1 407 ? 140.348 179.949 134.148 1.00 61.82  ? 418 LYS A HD2  1 
ATOM   6031 H  HD3  . LYS A 1 407 ? 141.186 181.282 134.381 1.00 61.60  ? 418 LYS A HD3  1 
ATOM   6032 H  HE2  . LYS A 1 407 ? 142.358 178.894 133.446 1.00 61.61  ? 418 LYS A HE2  1 
ATOM   6033 H  HE3  . LYS A 1 407 ? 141.914 180.074 132.477 1.00 62.31  ? 418 LYS A HE3  1 
ATOM   6034 H  HZ1  . LYS A 1 407 ? 144.115 180.269 132.914 1.00 62.22  ? 418 LYS A HZ1  1 
ATOM   6035 H  HZ2  . LYS A 1 407 ? 143.458 181.396 133.543 1.00 62.48  ? 418 LYS A HZ2  1 
ATOM   6036 H  HZ3  . LYS A 1 407 ? 143.898 180.274 134.347 1.00 61.37  ? 418 LYS A HZ3  1 
ATOM   6037 N  N    . TYR A 1 408 ? 142.045 181.186 139.290 1.00 48.31  ? 419 TYR A N    1 
ATOM   6038 C  CA   . TYR A 1 408 ? 143.274 181.680 139.900 1.00 52.59  ? 419 TYR A CA   1 
ATOM   6039 C  C    . TYR A 1 408 ? 143.679 180.815 141.087 1.00 63.22  ? 419 TYR A C    1 
ATOM   6040 O  O    . TYR A 1 408 ? 144.868 180.540 141.284 1.00 65.22  ? 419 TYR A O    1 
ATOM   6041 C  CB   . TYR A 1 408 ? 143.113 183.136 140.329 1.00 55.65  ? 419 TYR A CB   1 
ATOM   6042 C  CG   . TYR A 1 408 ? 144.371 183.712 140.936 1.00 57.74  ? 419 TYR A CG   1 
ATOM   6043 C  CD1  . TYR A 1 408 ? 145.406 184.167 140.133 1.00 54.33  ? 419 TYR A CD1  1 
ATOM   6044 C  CD2  . TYR A 1 408 ? 144.525 183.796 142.310 1.00 65.85  ? 419 TYR A CD2  1 
ATOM   6045 C  CE1  . TYR A 1 408 ? 146.558 184.693 140.683 1.00 56.67  ? 419 TYR A CE1  1 
ATOM   6046 C  CE2  . TYR A 1 408 ? 145.671 184.322 142.871 1.00 67.39  ? 419 TYR A CE2  1 
ATOM   6047 C  CZ   . TYR A 1 408 ? 146.685 184.768 142.054 1.00 63.08  ? 419 TYR A CZ   1 
ATOM   6048 O  OH   . TYR A 1 408 ? 147.829 185.291 142.612 1.00 62.59  ? 419 TYR A OH   1 
ATOM   6049 H  H    . TYR A 1 408 ? 141.382 181.733 139.314 1.00 60.93  ? 419 TYR A H    1 
ATOM   6050 H  HA   . TYR A 1 408 ? 143.988 181.640 139.246 1.00 60.71  ? 419 TYR A HA   1 
ATOM   6051 H  HB2  . TYR A 1 408 ? 142.880 183.672 139.555 1.00 61.59  ? 419 TYR A HB2  1 
ATOM   6052 H  HB3  . TYR A 1 408 ? 142.410 183.192 140.996 1.00 61.68  ? 419 TYR A HB3  1 
ATOM   6053 H  HD1  . TYR A 1 408 ? 145.323 184.118 139.208 1.00 60.91  ? 419 TYR A HD1  1 
ATOM   6054 H  HD2  . TYR A 1 408 ? 143.842 183.498 142.862 1.00 62.57  ? 419 TYR A HD2  1 
ATOM   6055 H  HE1  . TYR A 1 408 ? 147.244 184.995 140.133 1.00 61.99  ? 419 TYR A HE1  1 
ATOM   6056 H  HE2  . TYR A 1 408 ? 145.758 184.373 143.795 1.00 62.91  ? 419 TYR A HE2  1 
ATOM   6057 H  HH   . TYR A 1 408 ? 147.765 185.292 143.450 1.00 62.87  ? 419 TYR A HH   1 
ATOM   6058 N  N    . PHE A 1 409 ? 142.709 180.388 141.899 1.00 76.07  ? 420 PHE A N    1 
ATOM   6059 C  CA   . PHE A 1 409 ? 143.009 179.446 142.973 1.00 72.39  ? 420 PHE A CA   1 
ATOM   6060 C  C    . PHE A 1 409 ? 143.064 178.003 142.494 1.00 74.48  ? 420 PHE A C    1 
ATOM   6061 O  O    . PHE A 1 409 ? 143.596 177.149 143.212 1.00 79.42  ? 420 PHE A O    1 
ATOM   6062 C  CB   . PHE A 1 409 ? 141.982 179.566 144.102 1.00 67.48  ? 420 PHE A CB   1 
ATOM   6063 C  CG   . PHE A 1 409 ? 142.094 180.838 144.900 1.00 70.94  ? 420 PHE A CG   1 
ATOM   6064 C  CD1  . PHE A 1 409 ? 142.979 181.839 144.537 1.00 72.97  ? 420 PHE A CD1  1 
ATOM   6065 C  CD2  . PHE A 1 409 ? 141.324 181.017 146.034 1.00 77.52  ? 420 PHE A CD2  1 
ATOM   6066 C  CE1  . PHE A 1 409 ? 143.081 182.996 145.280 1.00 76.37  ? 420 PHE A CE1  1 
ATOM   6067 C  CE2  . PHE A 1 409 ? 141.421 182.171 146.780 1.00 78.66  ? 420 PHE A CE2  1 
ATOM   6068 C  CZ   . PHE A 1 409 ? 142.302 183.162 146.403 1.00 78.06  ? 420 PHE A CZ   1 
ATOM   6069 H  H    . PHE A 1 409 ? 141.884 180.627 141.852 1.00 73.29  ? 420 PHE A H    1 
ATOM   6070 H  HA   . PHE A 1 409 ? 143.882 179.656 143.340 1.00 72.52  ? 420 PHE A HA   1 
ATOM   6071 H  HB2  . PHE A 1 409 ? 141.092 179.537 143.718 1.00 73.03  ? 420 PHE A HB2  1 
ATOM   6072 H  HB3  . PHE A 1 409 ? 142.100 178.822 144.712 1.00 72.55  ? 420 PHE A HB3  1 
ATOM   6073 H  HD1  . PHE A 1 409 ? 143.508 181.737 143.779 1.00 72.67  ? 420 PHE A HD1  1 
ATOM   6074 H  HD2  . PHE A 1 409 ? 140.731 180.352 146.292 1.00 74.16  ? 420 PHE A HD2  1 
ATOM   6075 H  HE1  . PHE A 1 409 ? 143.675 183.663 145.022 1.00 73.55  ? 420 PHE A HE1  1 
ATOM   6076 H  HE2  . PHE A 1 409 ? 140.894 182.279 147.538 1.00 74.24  ? 420 PHE A HE2  1 
ATOM   6077 H  HZ   . PHE A 1 409 ? 142.369 183.942 146.904 1.00 74.20  ? 420 PHE A HZ   1 
ATOM   6078 N  N    . GLY A 1 410 ? 142.535 177.708 141.310 1.00 69.00  ? 421 GLY A N    1 
ATOM   6079 C  CA   . GLY A 1 410 ? 142.637 176.387 140.733 1.00 73.42  ? 421 GLY A CA   1 
ATOM   6080 C  C    . GLY A 1 410 ? 141.494 175.451 141.055 1.00 71.62  ? 421 GLY A C    1 
ATOM   6081 O  O    . GLY A 1 410 ? 141.404 174.379 140.443 1.00 77.14  ? 421 GLY A O    1 
ATOM   6082 H  H    . GLY A 1 410 ? 142.109 178.270 140.818 1.00 71.20  ? 421 GLY A H    1 
ATOM   6083 H  HA2  . GLY A 1 410 ? 142.692 176.469 139.768 1.00 72.35  ? 421 GLY A HA2  1 
ATOM   6084 H  HA3  . GLY A 1 410 ? 143.455 175.970 141.045 1.00 72.22  ? 421 GLY A HA3  1 
ATOM   6085 N  N    . ASP A 1 411 ? 140.620 175.810 141.990 1.00 61.40  ? 422 ASP A N    1 
ATOM   6086 C  CA   . ASP A 1 411 ? 139.474 174.965 142.287 1.00 66.55  ? 422 ASP A CA   1 
ATOM   6087 C  C    . ASP A 1 411 ? 138.488 174.991 141.126 1.00 62.92  ? 422 ASP A C    1 
ATOM   6088 O  O    . ASP A 1 411 ? 138.450 175.938 140.335 1.00 61.76  ? 422 ASP A O    1 
ATOM   6089 C  CB   . ASP A 1 411 ? 138.790 175.422 143.576 1.00 71.71  ? 422 ASP A CB   1 
ATOM   6090 C  CG   . ASP A 1 411 ? 138.308 176.854 143.504 1.00 72.22  ? 422 ASP A CG   1 
ATOM   6091 O  OD1  . ASP A 1 411 ? 139.163 177.761 143.433 1.00 75.62  ? 422 ASP A OD1  1 
ATOM   6092 O  OD2  . ASP A 1 411 ? 137.079 177.074 143.518 1.00 71.09  ? 422 ASP A OD2  1 
ATOM   6093 H  H    . ASP A 1 411 ? 140.669 176.528 142.461 1.00 67.28  ? 422 ASP A H    1 
ATOM   6094 H  HA   . ASP A 1 411 ? 139.774 174.051 142.411 1.00 68.08  ? 422 ASP A HA   1 
ATOM   6095 H  HB2  . ASP A 1 411 ? 138.021 174.854 143.745 1.00 68.53  ? 422 ASP A HB2  1 
ATOM   6096 H  HB3  . ASP A 1 411 ? 139.420 175.353 144.310 1.00 68.73  ? 422 ASP A HB3  1 
ATOM   6097 N  N    . ALA A 1 412 ? 137.690 173.931 141.023 1.00 65.91  ? 423 ALA A N    1 
ATOM   6098 C  CA   . ALA A 1 412 ? 136.743 173.821 139.922 1.00 66.59  ? 423 ALA A CA   1 
ATOM   6099 C  C    . ALA A 1 412 ? 135.853 175.055 139.871 1.00 64.84  ? 423 ALA A C    1 
ATOM   6100 O  O    . ALA A 1 412 ? 135.341 175.516 140.895 1.00 66.65  ? 423 ALA A O    1 
ATOM   6101 C  CB   . ALA A 1 412 ? 135.894 172.559 140.076 1.00 67.20  ? 423 ALA A CB   1 
ATOM   6102 H  H    . ALA A 1 412 ? 137.679 173.269 141.572 1.00 66.36  ? 423 ALA A H    1 
ATOM   6103 H  HA   . ALA A 1 412 ? 137.230 173.761 139.085 1.00 66.02  ? 423 ALA A HA   1 
ATOM   6104 H  HB1  . ALA A 1 412 ? 135.273 172.504 139.333 1.00 66.11  ? 423 ALA A HB1  1 
ATOM   6105 H  HB2  . ALA A 1 412 ? 136.479 171.785 140.075 1.00 65.98  ? 423 ALA A HB2  1 
ATOM   6106 H  HB3  . ALA A 1 412 ? 135.407 172.606 140.913 1.00 66.04  ? 423 ALA A HB3  1 
ATOM   6107 N  N    . LEU A 1 413 ? 135.675 175.593 138.670 1.00 58.45  ? 424 LEU A N    1 
ATOM   6108 C  CA   . LEU A 1 413 ? 135.007 176.876 138.530 1.00 57.67  ? 424 LEU A CA   1 
ATOM   6109 C  C    . LEU A 1 413 ? 133.574 176.779 139.046 1.00 61.57  ? 424 LEU A C    1 
ATOM   6110 O  O    . LEU A 1 413 ? 132.836 175.868 138.645 1.00 66.60  ? 424 LEU A O    1 
ATOM   6111 C  CB   . LEU A 1 413 ? 135.019 177.332 137.070 1.00 61.53  ? 424 LEU A CB   1 
ATOM   6112 C  CG   . LEU A 1 413 ? 133.958 176.773 136.118 1.00 62.78  ? 424 LEU A CG   1 
ATOM   6113 C  CD1  . LEU A 1 413 ? 133.975 177.542 134.808 1.00 60.10  ? 424 LEU A CD1  1 
ATOM   6114 C  CD2  . LEU A 1 413 ? 134.175 175.289 135.876 1.00 62.64  ? 424 LEU A CD2  1 
ATOM   6115 H  H    . LEU A 1 413 ? 135.930 175.238 137.930 1.00 61.50  ? 424 LEU A H    1 
ATOM   6116 H  HA   . LEU A 1 413 ? 135.493 177.533 139.049 1.00 61.74  ? 424 LEU A HA   1 
ATOM   6117 H  HB2  . LEU A 1 413 ? 134.924 178.297 137.060 1.00 61.50  ? 424 LEU A HB2  1 
ATOM   6118 H  HB3  . LEU A 1 413 ? 135.883 177.097 136.695 1.00 61.74  ? 424 LEU A HB3  1 
ATOM   6119 H  HG   . LEU A 1 413 ? 133.078 176.889 136.506 1.00 60.99  ? 424 LEU A HG   1 
ATOM   6120 H  HD11 . LEU A 1 413 ? 133.324 177.151 134.205 1.00 60.76  ? 424 LEU A HD11 1 
ATOM   6121 H  HD12 . LEU A 1 413 ? 133.748 178.469 134.985 1.00 61.17  ? 424 LEU A HD12 1 
ATOM   6122 H  HD13 . LEU A 1 413 ? 134.862 177.487 134.422 1.00 61.63  ? 424 LEU A HD13 1 
ATOM   6123 H  HD21 . LEU A 1 413 ? 133.526 174.977 135.227 1.00 61.70  ? 424 LEU A HD21 1 
ATOM   6124 H  HD22 . LEU A 1 413 ? 135.074 175.153 135.537 1.00 61.49  ? 424 LEU A HD22 1 
ATOM   6125 H  HD23 . LEU A 1 413 ? 134.062 174.813 136.714 1.00 61.51  ? 424 LEU A HD23 1 
ATOM   6126 N  N    . PRO A 1 414 ? 133.147 177.672 139.936 1.00 74.83  ? 425 PRO A N    1 
ATOM   6127 C  CA   . PRO A 1 414 ? 131.744 177.683 140.350 1.00 75.58  ? 425 PRO A CA   1 
ATOM   6128 C  C    . PRO A 1 414 ? 130.839 178.213 139.250 1.00 75.15  ? 425 PRO A C    1 
ATOM   6129 O  O    . PRO A 1 414 ? 131.263 178.935 138.345 1.00 73.38  ? 425 PRO A O    1 
ATOM   6130 C  CB   . PRO A 1 414 ? 131.753 178.620 141.560 1.00 79.73  ? 425 PRO A CB   1 
ATOM   6131 C  CG   . PRO A 1 414 ? 132.825 179.594 141.207 1.00 79.98  ? 425 PRO A CG   1 
ATOM   6132 C  CD   . PRO A 1 414 ? 133.910 178.710 140.652 1.00 77.54  ? 425 PRO A CD   1 
ATOM   6133 H  HA   . PRO A 1 414 ? 131.455 176.797 140.620 1.00 74.53  ? 425 PRO A HA   1 
ATOM   6134 H  HB2  . PRO A 1 414 ? 130.894 179.061 141.648 1.00 75.07  ? 425 PRO A HB2  1 
ATOM   6135 H  HB3  . PRO A 1 414 ? 131.979 178.127 142.364 1.00 75.57  ? 425 PRO A HB3  1 
ATOM   6136 H  HG2  . PRO A 1 414 ? 132.501 180.211 140.532 1.00 74.76  ? 425 PRO A HG2  1 
ATOM   6137 H  HG3  . PRO A 1 414 ? 133.129 180.068 141.992 1.00 75.20  ? 425 PRO A HG3  1 
ATOM   6138 H  HD2  . PRO A 1 414 ? 134.478 179.205 140.046 1.00 73.99  ? 425 PRO A HD2  1 
ATOM   6139 H  HD3  . PRO A 1 414 ? 134.421 178.311 141.373 1.00 74.72  ? 425 PRO A HD3  1 
ATOM   6140 N  N    . ALA A 1 415 ? 129.567 177.838 139.343 1.00 88.47  ? 426 ALA A N    1 
ATOM   6141 C  CA   . ALA A 1 415 ? 128.526 178.338 138.452 1.00 91.67  ? 426 ALA A CA   1 
ATOM   6142 C  C    . ALA A 1 415 ? 127.506 179.076 139.306 1.00 93.05  ? 426 ALA A C    1 
ATOM   6143 O  O    . ALA A 1 415 ? 126.808 178.459 140.119 1.00 91.26  ? 426 ALA A O    1 
ATOM   6144 C  CB   . ALA A 1 415 ? 127.873 177.201 137.668 1.00 88.13  ? 426 ALA A CB   1 
ATOM   6145 H  H    . ALA A 1 415 ? 129.276 177.283 139.932 1.00 88.00  ? 426 ALA A H    1 
ATOM   6146 H  HA   . ALA A 1 415 ? 128.911 178.966 137.822 1.00 88.97  ? 426 ALA A HA   1 
ATOM   6147 H  HB1  . ALA A 1 415 ? 128.551 176.754 137.137 1.00 88.37  ? 426 ALA A HB1  1 
ATOM   6148 H  HB2  . ALA A 1 415 ? 127.474 176.575 138.293 1.00 88.96  ? 426 ALA A HB2  1 
ATOM   6149 H  HB3  . ALA A 1 415 ? 127.190 177.572 137.089 1.00 88.59  ? 426 ALA A HB3  1 
ATOM   6150 N  N    . CYS A 1 416 ? 127.421 180.391 139.126 1.00 93.69  ? 427 CYS A N    1 
ATOM   6151 C  CA   . CYS A 1 416 ? 126.540 181.229 139.933 1.00 90.94  ? 427 CYS A CA   1 
ATOM   6152 C  C    . CYS A 1 416 ? 125.184 181.228 139.242 1.00 91.41  ? 427 CYS A C    1 
ATOM   6153 O  O    . CYS A 1 416 ? 125.017 181.845 138.188 1.00 93.08  ? 427 CYS A O    1 
ATOM   6154 C  CB   . CYS A 1 416 ? 127.079 182.650 140.036 1.00 90.01  ? 427 CYS A CB   1 
ATOM   6155 S  SG   . CYS A 1 416 ? 128.663 182.843 140.858 1.00 94.76  ? 427 CYS A SG   1 
ATOM   6156 H  H    . CYS A 1 416 ? 127.871 180.826 138.536 1.00 90.92  ? 427 CYS A H    1 
ATOM   6157 H  HA   . CYS A 1 416 ? 126.445 180.857 140.824 1.00 90.61  ? 427 CYS A HA   1 
ATOM   6158 H  HB2  . CYS A 1 416 ? 127.144 183.022 139.160 1.00 91.17  ? 427 CYS A HB2  1 
ATOM   6159 H  HB3  . CYS A 1 416 ? 126.439 183.169 140.548 1.00 89.97  ? 427 CYS A HB3  1 
ATOM   6160 N  N    . ALA A 1 417 ? 124.208 180.526 139.818 1.00 89.65  ? 428 ALA A N    1 
ATOM   6161 C  CA   . ALA A 1 417 ? 122.860 180.597 139.266 1.00 89.65  ? 428 ALA A CA   1 
ATOM   6162 C  C    . ALA A 1 417 ? 122.397 182.045 139.180 1.00 86.37  ? 428 ALA A C    1 
ATOM   6163 O  O    . ALA A 1 417 ? 121.828 182.468 138.167 1.00 82.26  ? 428 ALA A O    1 
ATOM   6164 C  CB   . ALA A 1 417 ? 121.896 179.770 140.116 1.00 87.12  ? 428 ALA A CB   1 
ATOM   6165 H  H    . ALA A 1 417 ? 124.297 180.017 140.506 1.00 86.58  ? 428 ALA A H    1 
ATOM   6166 H  HA   . ALA A 1 417 ? 122.866 180.228 138.369 1.00 86.59  ? 428 ALA A HA   1 
ATOM   6167 H  HB1  . ALA A 1 417 ? 121.009 179.819 139.725 1.00 86.23  ? 428 ALA A HB1  1 
ATOM   6168 H  HB2  . ALA A 1 417 ? 122.202 178.849 140.129 1.00 86.28  ? 428 ALA A HB2  1 
ATOM   6169 H  HB3  . ALA A 1 417 ? 121.882 180.128 141.017 1.00 86.20  ? 428 ALA A HB3  1 
ATOM   6170 N  N    . LYS A 1 418 ? 122.652 182.819 140.231 1.00 69.86  ? 429 LYS A N    1 
ATOM   6171 C  CA   . LYS A 1 418 ? 122.433 184.258 140.240 1.00 63.85  ? 429 LYS A CA   1 
ATOM   6172 C  C    . LYS A 1 418 ? 123.324 184.843 141.324 1.00 62.91  ? 429 LYS A C    1 
ATOM   6173 O  O    . LYS A 1 418 ? 123.940 184.116 142.107 1.00 59.34  ? 429 LYS A O    1 
ATOM   6174 C  CB   . LYS A 1 418 ? 120.959 184.612 140.481 1.00 67.32  ? 429 LYS A CB   1 
ATOM   6175 C  CG   . LYS A 1 418 ? 120.036 184.523 139.258 1.00 68.99  ? 429 LYS A CG   1 
ATOM   6176 C  CD   . LYS A 1 418 ? 120.505 185.373 138.077 1.00 67.75  ? 429 LYS A CD   1 
ATOM   6177 C  CE   . LYS A 1 418 ? 119.821 184.962 136.783 1.00 66.84  ? 429 LYS A CE   1 
ATOM   6178 N  NZ   . LYS A 1 418 ? 120.270 183.623 136.310 1.00 67.79  ? 429 LYS A NZ   1 
ATOM   6179 H  H    . LYS A 1 418 ? 122.963 182.520 140.975 1.00 68.57  ? 429 LYS A H    1 
ATOM   6180 H  HA   . LYS A 1 418 ? 122.723 184.628 139.395 1.00 66.96  ? 429 LYS A HA   1 
ATOM   6181 H  HB2  . LYS A 1 418 ? 120.606 184.009 141.153 1.00 67.97  ? 429 LYS A HB2  1 
ATOM   6182 H  HB3  . LYS A 1 418 ? 120.913 185.523 140.810 1.00 66.81  ? 429 LYS A HB3  1 
ATOM   6183 H  HG2  . LYS A 1 418 ? 119.979 183.600 138.968 1.00 68.00  ? 429 LYS A HG2  1 
ATOM   6184 H  HG3  . LYS A 1 418 ? 119.154 184.836 139.513 1.00 67.74  ? 429 LYS A HG3  1 
ATOM   6185 H  HD2  . LYS A 1 418 ? 120.289 186.303 138.249 1.00 67.73  ? 429 LYS A HD2  1 
ATOM   6186 H  HD3  . LYS A 1 418 ? 121.457 185.271 137.942 1.00 67.19  ? 429 LYS A HD3  1 
ATOM   6187 H  HE2  . LYS A 1 418 ? 118.863 184.926 136.926 1.00 67.12  ? 429 LYS A HE2  1 
ATOM   6188 H  HE3  . LYS A 1 418 ? 120.031 185.610 136.093 1.00 67.41  ? 429 LYS A HE3  1 
ATOM   6189 H  HZ1  . LYS A 1 418 ? 119.895 183.437 135.525 1.00 67.34  ? 429 LYS A HZ1  1 
ATOM   6190 H  HZ2  . LYS A 1 418 ? 121.155 183.615 136.217 1.00 68.04  ? 429 LYS A HZ2  1 
ATOM   6191 H  HZ3  . LYS A 1 418 ? 120.036 182.997 136.898 1.00 67.89  ? 429 LYS A HZ3  1 
ATOM   6192 N  N    . GLY A 1 419 ? 123.400 186.169 141.352 1.00 83.91  ? 430 GLY A N    1 
ATOM   6193 C  CA   . GLY A 1 419 ? 124.226 186.850 142.326 1.00 92.20  ? 430 GLY A CA   1 
ATOM   6194 C  C    . GLY A 1 419 ? 125.655 187.077 141.896 1.00 90.59  ? 430 GLY A C    1 
ATOM   6195 O  O    . GLY A 1 419 ? 126.528 187.234 142.757 1.00 89.65  ? 430 GLY A O    1 
ATOM   6196 H  H    . GLY A 1 419 ? 122.981 186.693 140.815 1.00 85.54  ? 430 GLY A H    1 
ATOM   6197 H  HA2  . GLY A 1 419 ? 123.831 187.714 142.522 1.00 87.31  ? 430 GLY A HA2  1 
ATOM   6198 H  HA3  . GLY A 1 419 ? 124.238 186.334 143.148 1.00 87.52  ? 430 GLY A HA3  1 
ATOM   6199 N  N    . CYS A 1 420 ? 125.924 187.097 140.594 1.00 89.81  ? 431 CYS A N    1 
ATOM   6200 C  CA   . CYS A 1 420 ? 127.261 187.326 140.069 1.00 89.79  ? 431 CYS A CA   1 
ATOM   6201 C  C    . CYS A 1 420 ? 127.157 188.297 138.903 1.00 87.72  ? 431 CYS A C    1 
ATOM   6202 O  O    . CYS A 1 420 ? 126.170 188.293 138.162 1.00 90.10  ? 431 CYS A O    1 
ATOM   6203 C  CB   . CYS A 1 420 ? 127.914 186.004 139.637 1.00 89.61  ? 431 CYS A CB   1 
ATOM   6204 S  SG   . CYS A 1 420 ? 129.619 186.111 139.055 1.00 95.89  ? 431 CYS A SG   1 
ATOM   6205 H  H    . CYS A 1 420 ? 125.332 186.977 139.981 1.00 88.23  ? 431 CYS A H    1 
ATOM   6206 H  HA   . CYS A 1 420 ? 127.813 187.731 140.755 1.00 88.29  ? 431 CYS A HA   1 
ATOM   6207 H  HB2  . CYS A 1 420 ? 127.904 185.406 140.398 1.00 87.95  ? 431 CYS A HB2  1 
ATOM   6208 H  HB3  . CYS A 1 420 ? 127.389 185.623 138.922 1.00 88.92  ? 431 CYS A HB3  1 
ATOM   6209 N  N    . ASP A 1 421 ? 128.181 189.138 138.753 1.00 63.17  ? 432 ASP A N    1 
ATOM   6210 C  CA   . ASP A 1 421 ? 128.114 190.210 137.764 1.00 64.75  ? 432 ASP A CA   1 
ATOM   6211 C  C    . ASP A 1 421 ? 127.830 189.661 136.373 1.00 70.99  ? 432 ASP A C    1 
ATOM   6212 O  O    . ASP A 1 421 ? 126.918 190.130 135.684 1.00 72.95  ? 432 ASP A O    1 
ATOM   6213 C  CB   . ASP A 1 421 ? 129.416 191.007 137.766 1.00 69.16  ? 432 ASP A CB   1 
ATOM   6214 C  CG   . ASP A 1 421 ? 129.356 192.220 136.859 1.00 74.22  ? 432 ASP A CG   1 
ATOM   6215 O  OD1  . ASP A 1 421 ? 128.693 193.211 137.233 1.00 71.72  ? 432 ASP A OD1  1 
ATOM   6216 O  OD2  . ASP A 1 421 ? 129.971 192.184 135.773 1.00 79.93  ? 432 ASP A OD2  1 
ATOM   6217 H  H    . ASP A 1 421 ? 128.912 189.111 139.205 1.00 71.78  ? 432 ASP A H    1 
ATOM   6218 H  HA   . ASP A 1 421 ? 127.392 190.813 138.001 1.00 72.17  ? 432 ASP A HA   1 
ATOM   6219 H  HB2  . ASP A 1 421 ? 129.586 191.315 138.666 1.00 72.12  ? 432 ASP A HB2  1 
ATOM   6220 H  HB3  . ASP A 1 421 ? 130.140 190.438 137.463 1.00 72.16  ? 432 ASP A HB3  1 
ATOM   6221 N  N    . HIS A 1 422 ? 128.613 188.675 135.934 1.00 73.45  ? 433 HIS A N    1 
ATOM   6222 C  CA   . HIS A 1 422 ? 128.395 188.102 134.611 1.00 70.00  ? 433 HIS A CA   1 
ATOM   6223 C  C    . HIS A 1 422 ? 127.220 187.136 134.582 1.00 72.40  ? 433 HIS A C    1 
ATOM   6224 O  O    . HIS A 1 422 ? 126.460 187.124 133.609 1.00 75.40  ? 433 HIS A O    1 
ATOM   6225 C  CB   . HIS A 1 422 ? 129.650 187.380 134.130 1.00 65.43  ? 433 HIS A CB   1 
ATOM   6226 C  CG   . HIS A 1 422 ? 129.503 186.767 132.773 1.00 73.82  ? 433 HIS A CG   1 
ATOM   6227 N  ND1  . HIS A 1 422 ? 129.340 185.412 132.581 1.00 76.41  ? 433 HIS A ND1  1 
ATOM   6228 C  CD2  . HIS A 1 422 ? 129.518 187.323 131.538 1.00 75.59  ? 433 HIS A CD2  1 
ATOM   6229 C  CE1  . HIS A 1 422 ? 129.248 185.162 131.287 1.00 74.01  ? 433 HIS A CE1  1 
ATOM   6230 N  NE2  . HIS A 1 422 ? 129.352 186.304 130.632 1.00 71.64  ? 433 HIS A NE2  1 
ATOM   6231 H  H    . HIS A 1 422 ? 129.265 188.327 136.374 1.00 72.57  ? 433 HIS A H    1 
ATOM   6232 H  HA   . HIS A 1 422 ? 128.206 188.820 133.986 1.00 72.06  ? 433 HIS A HA   1 
ATOM   6233 H  HB2  . HIS A 1 422 ? 130.383 188.014 134.093 1.00 70.88  ? 433 HIS A HB2  1 
ATOM   6234 H  HB3  . HIS A 1 422 ? 129.861 186.669 134.755 1.00 71.21  ? 433 HIS A HB3  1 
ATOM   6235 H  HD2  . HIS A 1 422 ? 129.615 188.227 131.341 1.00 72.64  ? 433 HIS A HD2  1 
ATOM   6236 H  HE1  . HIS A 1 422 ? 129.129 184.323 130.902 1.00 72.68  ? 433 HIS A HE1  1 
ATOM   6237 H  HE2  . HIS A 1 422 ? 129.322 186.395 129.778 1.00 71.76  ? 433 HIS A HE2  1 
ATOM   6238 N  N    . CYS A 1 423 ? 127.039 186.335 135.632 1.00 70.15  ? 434 CYS A N    1 
ATOM   6239 C  CA   . CYS A 1 423 ? 126.044 185.274 135.573 1.00 72.76  ? 434 CYS A CA   1 
ATOM   6240 C  C    . CYS A 1 423 ? 124.630 185.829 135.487 1.00 72.94  ? 434 CYS A C    1 
ATOM   6241 O  O    . CYS A 1 423 ? 123.714 185.107 135.078 1.00 74.24  ? 434 CYS A O    1 
ATOM   6242 C  CB   . CYS A 1 423 ? 126.188 184.367 136.789 1.00 72.95  ? 434 CYS A CB   1 
ATOM   6243 S  SG   . CYS A 1 423 ? 127.826 183.602 136.896 1.00 70.28  ? 434 CYS A SG   1 
ATOM   6244 H  H    . CYS A 1 423 ? 127.471 186.385 136.373 1.00 73.04  ? 434 CYS A H    1 
ATOM   6245 H  HA   . CYS A 1 423 ? 126.202 184.736 134.781 1.00 73.67  ? 434 CYS A HA   1 
ATOM   6246 H  HB2  . CYS A 1 423 ? 126.019 184.880 137.591 1.00 74.44  ? 434 CYS A HB2  1 
ATOM   6247 H  HB3  . CYS A 1 423 ? 125.539 183.651 136.717 1.00 74.27  ? 434 CYS A HB3  1 
ATOM   6248 N  N    . GLN A 1 424 ? 124.440 187.089 135.862 1.00 61.06  ? 435 GLN A N    1 
ATOM   6249 C  CA   . GLN A 1 424 ? 123.218 187.828 135.596 1.00 59.16  ? 435 GLN A CA   1 
ATOM   6250 C  C    . GLN A 1 424 ? 123.572 189.024 134.727 1.00 56.99  ? 435 GLN A C    1 
ATOM   6251 O  O    . GLN A 1 424 ? 124.691 189.537 134.791 1.00 53.29  ? 435 GLN A O    1 
ATOM   6252 C  CB   . GLN A 1 424 ? 122.544 188.294 136.892 1.00 64.80  ? 435 GLN A CB   1 
ATOM   6253 H  H    . GLN A 1 424 ? 125.027 187.552 136.287 1.00 62.51  ? 435 GLN A H    1 
ATOM   6254 H  HA   . GLN A 1 424 ? 122.595 187.266 135.109 1.00 60.99  ? 435 GLN A HA   1 
ATOM   6255 N  N    . ASN A 1 425 ? 122.621 189.434 133.889 1.00 67.01  ? 436 ASN A N    1 
ATOM   6256 C  CA   . ASN A 1 425 ? 122.789 190.514 132.920 1.00 70.65  ? 436 ASN A CA   1 
ATOM   6257 C  C    . ASN A 1 425 ? 124.210 190.539 132.358 1.00 71.85  ? 436 ASN A C    1 
ATOM   6258 O  O    . ASN A 1 425 ? 124.856 191.595 132.347 1.00 73.86  ? 436 ASN A O    1 
ATOM   6259 C  CB   . ASN A 1 425 ? 122.397 191.864 133.542 1.00 68.95  ? 436 ASN A CB   1 
ATOM   6260 C  CG   . ASN A 1 425 ? 123.342 192.331 134.645 1.00 72.60  ? 436 ASN A CG   1 
ATOM   6261 O  OD1  . ASN A 1 425 ? 124.462 191.850 134.784 1.00 74.49  ? 436 ASN A OD1  1 
ATOM   6262 N  ND2  . ASN A 1 425 ? 122.877 193.287 135.440 1.00 71.55  ? 436 ASN A ND2  1 
ATOM   6263 H  H    . ASN A 1 425 ? 121.836 189.085 133.864 1.00 69.61  ? 436 ASN A H    1 
ATOM   6264 H  HA   . ASN A 1 425 ? 122.187 190.354 132.177 1.00 70.12  ? 436 ASN A HA   1 
ATOM   6265 H  HB2  . ASN A 1 425 ? 122.398 192.540 132.846 1.00 70.09  ? 436 ASN A HB2  1 
ATOM   6266 H  HB3  . ASN A 1 425 ? 121.509 191.788 133.925 1.00 69.75  ? 436 ASN A HB3  1 
ATOM   6267 H  HD21 . ASN A 1 425 ? 122.087 193.605 135.315 1.00 70.59  ? 436 ASN A HD21 1 
ATOM   6268 H  HD22 . ASN A 1 425 ? 123.366 193.590 136.079 1.00 70.24  ? 436 ASN A HD22 1 
ATOM   6269 N  N    . PRO A 1 426 ? 124.723 189.405 131.865 1.00 67.39  ? 437 PRO A N    1 
ATOM   6270 C  CA   . PRO A 1 426 ? 126.096 189.407 131.326 1.00 68.22  ? 437 PRO A CA   1 
ATOM   6271 C  C    . PRO A 1 426 ? 126.301 190.428 130.226 1.00 62.38  ? 437 PRO A C    1 
ATOM   6272 O  O    . PRO A 1 426 ? 127.376 191.035 130.130 1.00 56.52  ? 437 PRO A O    1 
ATOM   6273 C  CB   . PRO A 1 426 ? 126.275 187.975 130.796 1.00 70.57  ? 437 PRO A CB   1 
ATOM   6274 C  CG   . PRO A 1 426 ? 124.900 187.410 130.681 1.00 66.43  ? 437 PRO A CG   1 
ATOM   6275 C  CD   . PRO A 1 426 ? 124.060 188.101 131.700 1.00 67.26  ? 437 PRO A CD   1 
ATOM   6276 H  HA   . PRO A 1 426 ? 126.737 189.567 132.036 1.00 66.74  ? 437 PRO A HA   1 
ATOM   6277 H  HB2  . PRO A 1 426 ? 126.698 188.007 129.924 1.00 67.19  ? 437 PRO A HB2  1 
ATOM   6278 H  HB3  . PRO A 1 426 ? 126.813 187.456 131.410 1.00 67.33  ? 437 PRO A HB3  1 
ATOM   6279 H  HG2  . PRO A 1 426 ? 124.557 187.577 129.789 1.00 65.95  ? 437 PRO A HG2  1 
ATOM   6280 H  HG3  . PRO A 1 426 ? 124.929 186.457 130.858 1.00 66.34  ? 437 PRO A HG3  1 
ATOM   6281 H  HD2  . PRO A 1 426 ? 123.156 188.219 131.368 1.00 66.30  ? 437 PRO A HD2  1 
ATOM   6282 H  HD3  . PRO A 1 426 ? 124.071 187.604 132.533 1.00 66.53  ? 437 PRO A HD3  1 
ATOM   6283 N  N    . THR A 1 427 ? 125.290 190.626 129.380 1.00 62.09  ? 438 THR A N    1 
ATOM   6284 C  CA   . THR A 1 427 ? 125.430 191.575 128.285 1.00 61.39  ? 438 THR A CA   1 
ATOM   6285 C  C    . THR A 1 427 ? 125.691 192.982 128.799 1.00 64.06  ? 438 THR A C    1 
ATOM   6286 O  O    . THR A 1 427 ? 126.378 193.759 128.137 1.00 62.71  ? 438 THR A O    1 
ATOM   6287 C  CB   . THR A 1 427 ? 124.181 191.551 127.404 1.00 65.11  ? 438 THR A CB   1 
ATOM   6288 O  OG1  . THR A 1 427 ? 123.037 191.935 128.178 1.00 73.05  ? 438 THR A OG1  1 
ATOM   6289 C  CG2  . THR A 1 427 ? 123.961 190.156 126.827 1.00 66.79  ? 438 THR A CG2  1 
ATOM   6290 H  H    . THR A 1 427 ? 124.528 190.230 129.419 1.00 66.10  ? 438 THR A H    1 
ATOM   6291 H  HA   . THR A 1 427 ? 126.186 191.313 127.737 1.00 65.46  ? 438 THR A HA   1 
ATOM   6292 H  HB   . THR A 1 427 ? 124.295 192.171 126.668 1.00 64.98  ? 438 THR A HB   1 
ATOM   6293 H  HG1  . THR A 1 427 ? 122.341 191.866 127.714 1.00 67.00  ? 438 THR A HG1  1 
ATOM   6294 H  HG21 . THR A 1 427 ? 123.204 190.163 126.221 1.00 66.51  ? 438 THR A HG21 1 
ATOM   6295 H  HG22 . THR A 1 427 ? 124.751 189.871 126.342 1.00 65.86  ? 438 THR A HG22 1 
ATOM   6296 H  HG23 . THR A 1 427 ? 123.786 189.524 127.541 1.00 66.43  ? 438 THR A HG23 1 
ATOM   6297 N  N    . ALA A 1 428 ? 125.162 193.330 129.973 1.00 78.56  ? 439 ALA A N    1 
ATOM   6298 C  CA   . ALA A 1 428 ? 125.453 194.644 130.541 1.00 78.96  ? 439 ALA A CA   1 
ATOM   6299 C  C    . ALA A 1 428 ? 126.932 194.782 130.885 1.00 74.52  ? 439 ALA A C    1 
ATOM   6300 O  O    . ALA A 1 428 ? 127.552 195.816 130.601 1.00 67.90  ? 439 ALA A O    1 
ATOM   6301 C  CB   . ALA A 1 428 ? 124.587 194.883 131.777 1.00 74.18  ? 439 ALA A CB   1 
ATOM   6302 H  H    . ALA A 1 428 ? 124.645 192.836 130.450 1.00 74.25  ? 439 ALA A H    1 
ATOM   6303 H  HA   . ALA A 1 428 ? 125.233 195.325 129.885 1.00 74.28  ? 439 ALA A HA   1 
ATOM   6304 H  HB1  . ALA A 1 428 ? 124.783 195.763 132.135 1.00 74.14  ? 439 ALA A HB1  1 
ATOM   6305 H  HB2  . ALA A 1 428 ? 123.653 194.830 131.521 1.00 73.70  ? 439 ALA A HB2  1 
ATOM   6306 H  HB3  . ALA A 1 428 ? 124.788 194.203 132.439 1.00 74.38  ? 439 ALA A HB3  1 
ATOM   6307 N  N    . VAL A 1 429 ? 127.517 193.752 131.497 1.00 66.20  ? 440 VAL A N    1 
ATOM   6308 C  CA   . VAL A 1 429 ? 128.946 193.783 131.791 1.00 57.09  ? 440 VAL A CA   1 
ATOM   6309 C  C    . VAL A 1 429 ? 129.747 193.848 130.500 1.00 62.97  ? 440 VAL A C    1 
ATOM   6310 O  O    . VAL A 1 429 ? 130.774 194.534 130.420 1.00 68.26  ? 440 VAL A O    1 
ATOM   6311 C  CB   . VAL A 1 429 ? 129.343 192.563 132.641 1.00 55.48  ? 440 VAL A CB   1 
ATOM   6312 H  H    . VAL A 1 429 ? 127.114 193.035 131.750 1.00 65.31  ? 440 VAL A H    1 
ATOM   6313 H  HA   . VAL A 1 429 ? 129.143 194.582 132.305 1.00 62.62  ? 440 VAL A HA   1 
ATOM   6314 N  N    . ARG A 1 430 ? 129.296 193.135 129.466 1.00 84.60  ? 441 ARG A N    1 
ATOM   6315 C  CA   . ARG A 1 430 ? 130.003 193.185 128.190 1.00 93.20  ? 441 ARG A CA   1 
ATOM   6316 C  C    . ARG A 1 430 ? 129.907 194.570 127.561 1.00 94.13  ? 441 ARG A C    1 
ATOM   6317 O  O    . ARG A 1 430 ? 130.861 195.041 126.934 1.00 94.49  ? 441 ARG A O    1 
ATOM   6318 C  CB   . ARG A 1 430 ? 129.459 192.121 127.237 1.00 92.51  ? 441 ARG A CB   1 
ATOM   6319 C  CG   . ARG A 1 430 ? 130.077 192.154 125.837 1.00 94.61  ? 441 ARG A CG   1 
ATOM   6320 C  CD   . ARG A 1 430 ? 131.603 192.078 125.869 1.00 93.18  ? 441 ARG A CD   1 
ATOM   6321 N  NE   . ARG A 1 430 ? 132.201 192.399 124.579 1.00 93.85  ? 441 ARG A NE   1 
ATOM   6322 C  CZ   . ARG A 1 430 ? 132.136 191.624 123.505 1.00 93.69  ? 441 ARG A CZ   1 
ATOM   6323 N  NH1  . ARG A 1 430 ? 131.509 190.460 123.528 1.00 91.71  ? 441 ARG A NH1  1 
ATOM   6324 N  NH2  . ARG A 1 430 ? 132.718 192.027 122.379 1.00 94.72  ? 441 ARG A NH2  1 
ATOM   6325 H  H    . ARG A 1 430 ? 128.602 192.627 129.477 1.00 87.03  ? 441 ARG A H    1 
ATOM   6326 H  HA   . ARG A 1 430 ? 130.939 192.996 128.357 1.00 90.16  ? 441 ARG A HA   1 
ATOM   6327 H  HB2  . ARG A 1 430 ? 129.634 191.246 127.617 1.00 89.75  ? 441 ARG A HB2  1 
ATOM   6328 H  HB3  . ARG A 1 430 ? 128.502 192.250 127.140 1.00 89.55  ? 441 ARG A HB3  1 
ATOM   6329 H  HG2  . ARG A 1 430 ? 129.751 191.393 125.332 1.00 91.12  ? 441 ARG A HG2  1 
ATOM   6330 H  HG3  . ARG A 1 430 ? 129.825 192.978 125.393 1.00 91.25  ? 441 ARG A HG3  1 
ATOM   6331 H  HD2  . ARG A 1 430 ? 131.953 192.712 126.512 1.00 90.59  ? 441 ARG A HD2  1 
ATOM   6332 H  HD3  . ARG A 1 430 ? 131.871 191.178 126.112 1.00 90.47  ? 441 ARG A HD3  1 
ATOM   6333 H  HE   . ARG A 1 430 ? 132.638 193.137 124.514 1.00 91.00  ? 441 ARG A HE   1 
ATOM   6334 H  HH11 . ARG A 1 430 ? 131.129 190.187 124.249 1.00 90.56  ? 441 ARG A HH11 1 
ATOM   6335 H  HH12 . ARG A 1 430 ? 131.481 189.974 122.818 1.00 90.74  ? 441 ARG A HH12 1 
ATOM   6336 H  HH21 . ARG A 1 430 ? 133.129 192.783 122.354 1.00 91.43  ? 441 ARG A HH21 1 
ATOM   6337 H  HH22 . ARG A 1 430 ? 132.684 191.533 121.676 1.00 91.17  ? 441 ARG A HH22 1 
ATOM   6338 N  N    . ARG A 1 431 ? 128.758 195.231 127.704 1.00 87.88  ? 442 ARG A N    1 
ATOM   6339 C  CA   . ARG A 1 431 ? 128.618 196.600 127.217 1.00 86.78  ? 442 ARG A CA   1 
ATOM   6340 C  C    . ARG A 1 431 ? 129.539 197.542 127.979 1.00 87.63  ? 442 ARG A C    1 
ATOM   6341 O  O    . ARG A 1 431 ? 130.125 198.459 127.395 1.00 92.02  ? 442 ARG A O    1 
ATOM   6342 C  CB   . ARG A 1 431 ? 127.162 197.049 127.339 1.00 89.74  ? 442 ARG A CB   1 
ATOM   6343 C  CG   . ARG A 1 431 ? 126.211 196.296 126.423 1.00 92.10  ? 442 ARG A CG   1 
ATOM   6344 C  CD   . ARG A 1 431 ? 124.767 196.721 126.629 1.00 90.66  ? 442 ARG A CD   1 
ATOM   6345 N  NE   . ARG A 1 431 ? 123.847 195.881 125.869 1.00 87.65  ? 442 ARG A NE   1 
ATOM   6346 C  CZ   . ARG A 1 431 ? 123.157 194.864 126.373 1.00 86.14  ? 442 ARG A CZ   1 
ATOM   6347 N  NH1  . ARG A 1 431 ? 123.256 194.520 127.647 1.00 87.36  ? 442 ARG A NH1  1 
ATOM   6348 N  NH2  . ARG A 1 431 ? 122.348 194.172 125.576 1.00 86.21  ? 442 ARG A NH2  1 
ATOM   6349 H  H    . ARG A 1 431 ? 128.051 194.912 128.077 1.00 85.79  ? 442 ARG A H    1 
ATOM   6350 H  HA   . ARG A 1 431 ? 128.866 196.630 126.280 1.00 87.01  ? 442 ARG A HA   1 
ATOM   6351 H  HB2  . ARG A 1 431 ? 126.867 196.909 128.253 1.00 86.48  ? 442 ARG A HB2  1 
ATOM   6352 H  HB3  . ARG A 1 431 ? 127.105 197.991 127.115 1.00 87.79  ? 442 ARG A HB3  1 
ATOM   6353 H  HG2  . ARG A 1 431 ? 126.447 196.490 125.503 1.00 88.10  ? 442 ARG A HG2  1 
ATOM   6354 H  HG3  . ARG A 1 431 ? 126.280 195.346 126.584 1.00 86.80  ? 442 ARG A HG3  1 
ATOM   6355 H  HD2  . ARG A 1 431 ? 124.546 196.666 127.571 1.00 87.22  ? 442 ARG A HD2  1 
ATOM   6356 H  HD3  . ARG A 1 431 ? 124.661 197.634 126.319 1.00 87.45  ? 442 ARG A HD3  1 
ATOM   6357 H  HE   . ARG A 1 431 ? 123.789 196.020 125.023 1.00 86.99  ? 442 ARG A HE   1 
ATOM   6358 H  HH11 . ARG A 1 431 ? 123.774 194.953 128.178 1.00 86.26  ? 442 ARG A HH11 1 
ATOM   6359 H  HH12 . ARG A 1 431 ? 122.798 193.856 127.946 1.00 86.27  ? 442 ARG A HH12 1 
ATOM   6360 H  HH21 . ARG A 1 431 ? 122.275 194.385 124.746 1.00 87.04  ? 442 ARG A HH21 1 
ATOM   6361 H  HH22 . ARG A 1 431 ? 121.897 193.511 125.891 1.00 86.84  ? 442 ARG A HH22 1 
ATOM   6362 N  N    . ARG A 1 432 ? 129.675 197.333 129.289 1.00 88.09  ? 443 ARG A N    1 
ATOM   6363 C  CA   . ARG A 1 432 ? 130.626 198.124 130.063 1.00 92.97  ? 443 ARG A CA   1 
ATOM   6364 C  C    . ARG A 1 432 ? 132.051 197.898 129.569 1.00 97.11  ? 443 ARG A C    1 
ATOM   6365 O  O    . ARG A 1 432 ? 132.839 198.844 129.458 1.00 96.23  ? 443 ARG A O    1 
ATOM   6366 C  CB   . ARG A 1 432 ? 130.511 197.779 131.547 1.00 91.92  ? 443 ARG A CB   1 
ATOM   6367 H  H    . ARG A 1 432 ? 129.235 196.751 129.745 1.00 90.08  ? 443 ARG A H    1 
ATOM   6368 H  HA   . ARG A 1 432 ? 130.417 199.065 129.955 1.00 92.17  ? 443 ARG A HA   1 
ATOM   6369 N  N    . LEU A 1 433 ? 132.399 196.646 129.267 1.00 87.45  ? 444 LEU A N    1 
ATOM   6370 C  CA   . LEU A 1 433 ? 133.728 196.349 128.737 1.00 77.96  ? 444 LEU A CA   1 
ATOM   6371 C  C    . LEU A 1 433 ? 133.941 197.017 127.383 1.00 77.05  ? 444 LEU A C    1 
ATOM   6372 O  O    . LEU A 1 433 ? 135.026 197.540 127.099 1.00 71.90  ? 444 LEU A O    1 
ATOM   6373 C  CB   . LEU A 1 433 ? 133.911 194.837 128.618 1.00 80.05  ? 444 LEU A CB   1 
ATOM   6374 C  CG   . LEU A 1 433 ? 134.235 194.108 129.922 1.00 83.70  ? 444 LEU A CG   1 
ATOM   6375 C  CD1  . LEU A 1 433 ? 133.866 192.635 129.816 1.00 81.73  ? 444 LEU A CD1  1 
ATOM   6376 C  CD2  . LEU A 1 433 ? 135.698 194.272 130.278 1.00 85.64  ? 444 LEU A CD2  1 
ATOM   6377 H  H    . LEU A 1 433 ? 131.890 195.959 129.360 1.00 82.94  ? 444 LEU A H    1 
ATOM   6378 H  HA   . LEU A 1 433 ? 134.398 196.689 129.350 1.00 81.30  ? 444 LEU A HA   1 
ATOM   6379 H  HB2  . LEU A 1 433 ? 133.091 194.456 128.268 1.00 81.80  ? 444 LEU A HB2  1 
ATOM   6380 H  HB3  . LEU A 1 433 ? 134.638 194.664 128.000 1.00 81.76  ? 444 LEU A HB3  1 
ATOM   6381 H  HG   . LEU A 1 433 ? 133.708 194.496 130.638 1.00 82.32  ? 444 LEU A HG   1 
ATOM   6382 H  HD11 . LEU A 1 433 ? 134.061 192.200 130.660 1.00 81.29  ? 444 LEU A HD11 1 
ATOM   6383 H  HD12 . LEU A 1 433 ? 132.920 192.560 129.616 1.00 81.18  ? 444 LEU A HD12 1 
ATOM   6384 H  HD13 . LEU A 1 433 ? 134.388 192.230 129.106 1.00 81.62  ? 444 LEU A HD13 1 
ATOM   6385 H  HD21 . LEU A 1 433 ? 135.823 193.994 131.198 1.00 81.75  ? 444 LEU A HD21 1 
ATOM   6386 H  HD22 . LEU A 1 433 ? 136.231 193.719 129.686 1.00 82.53  ? 444 LEU A HD22 1 
ATOM   6387 H  HD23 . LEU A 1 433 ? 135.946 195.204 130.178 1.00 82.47  ? 444 LEU A HD23 1 
ATOM   6388 N  N    . GLU A 1 434 ? 132.919 196.990 126.527 1.00 90.92  ? 445 GLU A N    1 
ATOM   6389 C  CA   . GLU A 1 434 ? 133.018 197.643 125.226 1.00 91.59  ? 445 GLU A CA   1 
ATOM   6390 C  C    . GLU A 1 434 ? 133.191 199.146 125.384 1.00 87.07  ? 445 GLU A C    1 
ATOM   6391 O  O    . GLU A 1 434 ? 133.955 199.773 124.644 1.00 84.48  ? 445 GLU A O    1 
ATOM   6392 C  CB   . GLU A 1 434 ? 131.778 197.331 124.389 1.00 92.75  ? 445 GLU A CB   1 
ATOM   6393 C  CG   . GLU A 1 434 ? 131.770 195.934 123.790 1.00 92.46  ? 445 GLU A CG   1 
ATOM   6394 C  CD   . GLU A 1 434 ? 132.655 195.818 122.565 1.00 93.19  ? 445 GLU A CD   1 
ATOM   6395 O  OE1  . GLU A 1 434 ? 133.362 196.796 122.244 1.00 93.34  ? 445 GLU A OE1  1 
ATOM   6396 O  OE2  . GLU A 1 434 ? 132.644 194.747 121.922 1.00 94.38  ? 445 GLU A OE2  1 
ATOM   6397 H  H    . GLU A 1 434 ? 132.165 196.604 126.675 1.00 90.75  ? 445 GLU A H    1 
ATOM   6398 H  HA   . GLU A 1 434 ? 133.794 197.298 124.757 1.00 91.00  ? 445 GLU A HA   1 
ATOM   6399 H  HB2  . GLU A 1 434 ? 130.993 197.415 124.952 1.00 90.62  ? 445 GLU A HB2  1 
ATOM   6400 H  HB3  . GLU A 1 434 ? 131.726 197.968 123.658 1.00 91.66  ? 445 GLU A HB3  1 
ATOM   6401 H  HG2  . GLU A 1 434 ? 132.091 195.304 124.454 1.00 90.65  ? 445 GLU A HG2  1 
ATOM   6402 H  HG3  . GLU A 1 434 ? 130.864 195.707 123.529 1.00 91.29  ? 445 GLU A HG3  1 
ATOM   6403 N  N    . ALA A 1 435 ? 132.479 199.744 126.339 1.00 91.84  ? 446 ALA A N    1 
ATOM   6404 C  CA   . ALA A 1 435 ? 132.667 201.163 126.617 1.00 95.47  ? 446 ALA A CA   1 
ATOM   6405 C  C    . ALA A 1 435 ? 134.081 201.434 127.111 1.00 91.04  ? 446 ALA A C    1 
ATOM   6406 O  O    . ALA A 1 435 ? 134.688 202.449 126.753 1.00 94.10  ? 446 ALA A O    1 
ATOM   6407 C  CB   . ALA A 1 435 ? 131.638 201.637 127.643 1.00 97.81  ? 446 ALA A CB   1 
ATOM   6408 H  H    . ALA A 1 435 ? 131.890 199.357 126.831 1.00 94.26  ? 446 ALA A H    1 
ATOM   6409 H  HA   . ALA A 1 435 ? 132.532 201.667 125.800 1.00 94.33  ? 446 ALA A HA   1 
ATOM   6410 H  HB1  . ALA A 1 435 ? 131.767 202.585 127.802 1.00 94.77  ? 446 ALA A HB1  1 
ATOM   6411 H  HB2  . ALA A 1 435 ? 130.748 201.478 127.292 1.00 94.83  ? 446 ALA A HB2  1 
ATOM   6412 H  HB3  . ALA A 1 435 ? 131.763 201.141 128.467 1.00 94.75  ? 446 ALA A HB3  1 
ATOM   6413 N  N    . LEU A 1 436 ? 134.617 200.541 127.945 1.00 97.51  ? 447 LEU A N    1 
ATOM   6414 C  CA   . LEU A 1 436 ? 136.000 200.685 128.388 1.00 109.02 ? 447 LEU A CA   1 
ATOM   6415 C  C    . LEU A 1 436 ? 136.953 200.664 127.202 1.00 111.76 ? 447 LEU A C    1 
ATOM   6416 O  O    . LEU A 1 436 ? 137.884 201.475 127.125 1.00 115.03 ? 447 LEU A O    1 
ATOM   6417 C  CB   . LEU A 1 436 ? 136.353 199.570 129.373 1.00 110.72 ? 447 LEU A CB   1 
ATOM   6418 C  CG   . LEU A 1 436 ? 137.713 199.692 130.064 1.00 112.15 ? 447 LEU A CG   1 
ATOM   6419 C  CD1  . LEU A 1 436 ? 137.651 200.685 131.214 1.00 109.52 ? 447 LEU A CD1  1 
ATOM   6420 C  CD2  . LEU A 1 436 ? 138.193 198.330 130.544 1.00 107.77 ? 447 LEU A CD2  1 
ATOM   6421 H  H    . LEU A 1 436 ? 134.207 199.855 128.263 1.00 103.89 ? 447 LEU A H    1 
ATOM   6422 H  HA   . LEU A 1 436 ? 136.101 201.534 128.844 1.00 107.29 ? 447 LEU A HA   1 
ATOM   6423 H  HB2  . LEU A 1 436 ? 135.676 199.550 130.067 1.00 106.33 ? 447 LEU A HB2  1 
ATOM   6424 H  HB3  . LEU A 1 436 ? 136.347 198.727 128.893 1.00 105.90 ? 447 LEU A HB3  1 
ATOM   6425 H  HG   . LEU A 1 436 ? 138.363 200.023 129.424 1.00 107.58 ? 447 LEU A HG   1 
ATOM   6426 H  HD11 . LEU A 1 436 ? 136.951 200.413 131.828 1.00 106.69 ? 447 LEU A HD11 1 
ATOM   6427 H  HD12 . LEU A 1 436 ? 138.507 200.692 131.670 1.00 106.92 ? 447 LEU A HD12 1 
ATOM   6428 H  HD13 . LEU A 1 436 ? 137.456 201.566 130.860 1.00 107.14 ? 447 LEU A HD13 1 
ATOM   6429 H  HD21 . LEU A 1 436 ? 138.960 198.452 131.125 1.00 106.14 ? 447 LEU A HD21 1 
ATOM   6430 H  HD22 . LEU A 1 436 ? 137.475 197.897 131.030 1.00 106.07 ? 447 LEU A HD22 1 
ATOM   6431 H  HD23 . LEU A 1 436 ? 138.441 197.794 129.775 1.00 106.18 ? 447 LEU A HD23 1 
ATOM   6432 N  N    . GLU A 1 437 ? 136.735 199.740 126.266 1.00 114.09 ? 448 GLU A N    1 
ATOM   6433 C  CA   . GLU A 1 437 ? 137.564 199.692 125.066 1.00 116.68 ? 448 GLU A CA   1 
ATOM   6434 C  C    . GLU A 1 437 ? 137.422 200.974 124.256 1.00 117.16 ? 448 GLU A C    1 
ATOM   6435 O  O    . GLU A 1 437 ? 138.409 201.498 123.725 1.00 117.69 ? 448 GLU A O    1 
ATOM   6436 C  CB   . GLU A 1 437 ? 137.188 198.478 124.217 1.00 114.10 ? 448 GLU A CB   1 
ATOM   6437 C  CG   . GLU A 1 437 ? 137.531 197.141 124.855 1.00 113.51 ? 448 GLU A CG   1 
ATOM   6438 C  CD   . GLU A 1 437 ? 136.549 196.048 124.480 1.00 113.46 ? 448 GLU A CD   1 
ATOM   6439 O  OE1  . GLU A 1 437 ? 136.302 195.859 123.271 1.00 112.59 ? 448 GLU A OE1  1 
ATOM   6440 O  OE2  . GLU A 1 437 ? 136.027 195.377 125.395 1.00 113.69 ? 448 GLU A OE2  1 
ATOM   6441 H  H    . GLU A 1 437 ? 136.121 199.138 126.302 1.00 111.54 ? 448 GLU A H    1 
ATOM   6442 H  HA   . GLU A 1 437 ? 138.494 199.601 125.327 1.00 113.63 ? 448 GLU A HA   1 
ATOM   6443 H  HB2  . GLU A 1 437 ? 136.231 198.492 124.058 1.00 112.46 ? 448 GLU A HB2  1 
ATOM   6444 H  HB3  . GLU A 1 437 ? 137.661 198.531 123.371 1.00 113.25 ? 448 GLU A HB3  1 
ATOM   6445 H  HG2  . GLU A 1 437 ? 138.413 196.867 124.560 1.00 113.40 ? 448 GLU A HG2  1 
ATOM   6446 H  HG3  . GLU A 1 437 ? 137.518 197.238 125.820 1.00 112.81 ? 448 GLU A HG3  1 
ATOM   6447 N  N    . ARG A 1 438 ? 136.197 201.491 124.150 1.00 109.45 ? 449 ARG A N    1 
ATOM   6448 C  CA   . ARG A 1 438 ? 135.966 202.733 123.419 1.00 108.89 ? 449 ARG A CA   1 
ATOM   6449 C  C    . ARG A 1 438 ? 136.741 203.885 124.045 1.00 108.51 ? 449 ARG A C    1 
ATOM   6450 O  O    . ARG A 1 438 ? 137.383 204.675 123.343 1.00 108.34 ? 449 ARG A O    1 
ATOM   6451 C  CB   . ARG A 1 438 ? 134.466 203.037 123.391 1.00 107.86 ? 449 ARG A CB   1 
ATOM   6452 C  CG   . ARG A 1 438 ? 134.082 204.336 122.690 1.00 110.27 ? 449 ARG A CG   1 
ATOM   6453 C  CD   . ARG A 1 438 ? 134.283 204.250 121.187 1.00 108.35 ? 449 ARG A CD   1 
ATOM   6454 N  NE   . ARG A 1 438 ? 135.651 204.566 120.796 1.00 108.45 ? 449 ARG A NE   1 
ATOM   6455 C  CZ   . ARG A 1 438 ? 136.134 204.415 119.570 1.00 109.80 ? 449 ARG A CZ   1 
ATOM   6456 N  NH1  . ARG A 1 438 ? 135.384 203.952 118.583 1.00 109.67 ? 449 ARG A NH1  1 
ATOM   6457 N  NH2  . ARG A 1 438 ? 137.401 204.737 119.328 1.00 110.18 ? 449 ARG A NH2  1 
ATOM   6458 H  H    . ARG A 1 438 ? 135.489 201.144 124.491 1.00 107.62 ? 449 ARG A H    1 
ATOM   6459 H  HA   . ARG A 1 438 ? 136.270 202.625 122.504 1.00 108.86 ? 449 ARG A HA   1 
ATOM   6460 H  HB2  . ARG A 1 438 ? 134.012 202.312 122.934 1.00 108.27 ? 449 ARG A HB2  1 
ATOM   6461 H  HB3  . ARG A 1 438 ? 134.147 203.095 124.305 1.00 108.10 ? 449 ARG A HB3  1 
ATOM   6462 H  HG2  . ARG A 1 438 ? 133.144 204.517 122.856 1.00 109.00 ? 449 ARG A HG2  1 
ATOM   6463 H  HG3  . ARG A 1 438 ? 134.625 205.065 123.028 1.00 109.01 ? 449 ARG A HG3  1 
ATOM   6464 H  HD2  . ARG A 1 438 ? 134.084 203.349 120.889 1.00 108.56 ? 449 ARG A HD2  1 
ATOM   6465 H  HD3  . ARG A 1 438 ? 133.691 204.883 120.751 1.00 108.66 ? 449 ARG A HD3  1 
ATOM   6466 H  HE   . ARG A 1 438 ? 136.176 204.887 121.397 1.00 108.68 ? 449 ARG A HE   1 
ATOM   6467 H  HH11 . ARG A 1 438 ? 134.563 203.741 118.726 1.00 108.65 ? 449 ARG A HH11 1 
ATOM   6468 H  HH12 . ARG A 1 438 ? 135.718 203.863 117.795 1.00 108.88 ? 449 ARG A HH12 1 
ATOM   6469 H  HH21 . ARG A 1 438 ? 137.897 205.039 119.963 1.00 109.01 ? 449 ARG A HH21 1 
ATOM   6470 H  HH22 . ARG A 1 438 ? 137.725 204.644 118.537 1.00 108.83 ? 449 ARG A HH22 1 
ATOM   6471 N  N    . SER A 1 439 ? 136.693 203.996 125.374 1.00 113.69 ? 450 SER A N    1 
ATOM   6472 C  CA   . SER A 1 439 ? 137.430 205.053 126.056 1.00 115.51 ? 450 SER A CA   1 
ATOM   6473 C  C    . SER A 1 439 ? 138.933 204.857 125.912 1.00 117.65 ? 450 SER A C    1 
ATOM   6474 O  O    . SER A 1 439 ? 139.676 205.826 125.715 1.00 118.39 ? 450 SER A O    1 
ATOM   6475 C  CB   . SER A 1 439 ? 137.035 205.096 127.532 1.00 114.99 ? 450 SER A CB   1 
ATOM   6476 O  OG   . SER A 1 439 ? 137.291 203.855 128.165 1.00 117.38 ? 450 SER A OG   1 
ATOM   6477 H  H    . SER A 1 439 ? 136.246 203.477 125.894 1.00 114.63 ? 450 SER A H    1 
ATOM   6478 H  HA   . SER A 1 439 ? 137.199 205.907 125.659 1.00 115.50 ? 450 SER A HA   1 
ATOM   6479 H  HB2  . SER A 1 439 ? 137.550 205.788 127.977 1.00 115.31 ? 450 SER A HB2  1 
ATOM   6480 H  HB3  . SER A 1 439 ? 136.088 205.294 127.599 1.00 115.22 ? 450 SER A HB3  1 
ATOM   6481 H  HG   . SER A 1 439 ? 136.846 203.246 127.793 1.00 115.51 ? 450 SER A HG   1 
ATOM   6482 N  N    . SER A 1 440 ? 139.399 203.616 126.006 1.00 126.96 ? 451 SER A N    1 
ATOM   6483 C  CA   . SER A 1 440 ? 140.820 203.317 125.888 1.00 126.09 ? 451 SER A CA   1 
ATOM   6484 C  C    . SER A 1 440 ? 141.033 201.865 125.478 1.00 124.86 ? 451 SER A C    1 
ATOM   6485 O  O    . SER A 1 440 ? 141.176 201.559 124.295 1.00 125.07 ? 451 SER A O    1 
ATOM   6486 C  CB   . SER A 1 440 ? 141.539 203.602 127.209 1.00 126.47 ? 451 SER A CB   1 
ATOM   6487 O  OG   . SER A 1 440 ? 142.874 203.130 127.174 1.00 127.28 ? 451 SER A OG   1 
ATOM   6488 H  H    . SER A 1 440 ? 138.906 202.923 126.139 1.00 124.96 ? 451 SER A H    1 
ATOM   6489 H  HA   . SER A 1 440 ? 141.209 203.885 125.204 1.00 125.54 ? 451 SER A HA   1 
ATOM   6490 H  HB2  . SER A 1 440 ? 141.547 204.560 127.363 1.00 125.56 ? 451 SER A HB2  1 
ATOM   6491 H  HB3  . SER A 1 440 ? 141.065 203.155 127.927 1.00 125.56 ? 451 SER A HB3  1 
ATOM   6492 H  HG   . SER A 1 440 ? 143.297 203.510 126.556 1.00 125.83 ? 451 SER A HG   1 
HETATM 6493 ZN ZN   . ZN  B 2 .   ? 129.207 183.825 138.781 1.00 93.33  ? 501 ZN  A ZN   1 
# 
